data_9K0A
# 
_entry.id   9K0A 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9K0A         pdb_00009k0a 10.2210/pdb9k0a/pdb 
WWPDB D_1300052535 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-18 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9K0A 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-15 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              tmori@mol.f.u-tokyo.ac.jp 
_pdbx_contact_author.name_first         Takahiro 
_pdbx_contact_author.name_last          Mori 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2754-5858 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mori, T.'   1 ? 
'Renata, H.' 2 ? 
'Abe, I.'    3 ? 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? ?  ? ? primary 'To Be Published'                                ?      0353 ?         ? ? ?  ? ?   ?   
'Structure of Pictet-Spenglerases KslB in complex with product'                                              ?    ? ? ?        ? ? 
? ? ? ? ? ? ? DK ? ? 1       'Acta Crystallogr., Sect. D: Biol. Crystallogr.' ABCRE6 0766 0907-4449 ? ? 75 ? 861 877 
'Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix' 2019 ? 
10.1107/S2059798319011471 31588918 ? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Mori, T.'          1  ?                   
primary 'Renata, H.'        2  ?                   
primary 'Abe, I.'           3  ?                   
1       'Liebschner, D.'    4  0000-0003-3921-3209 
1       'Afonine, P.V.'     5  0000-0002-5052-991X 
1       'Baker, M.L.'       6  ?                   
1       'Bunkoczi, G.'      7  ?                   
1       'Chen, V.B.'        8  0000-0003-2492-979X 
1       'Croll, T.I.'       9  ?                   
1       'Hintze, B.'        10 0000-0002-4871-2096 
1       'Hung, L.W.'        11 0000-0001-6690-8458 
1       'Jain, S.'          12 ?                   
1       'McCoy, A.J.'       13 ?                   
1       'Moriarty, N.W.'    14 0000-0001-8857-9464 
1       'Oeffner, R.D.'     15 0000-0003-3107-2202 
1       'Poon, B.K.'        16 0000-0001-9633-6067 
1       'Prisant, M.G.'     17 ?                   
1       'Read, R.J.'        18 0000-0001-8273-0047 
1       'Richardson, J.S.'  19 0000-0002-3311-2944 
1       'Richardson, D.C.'  20 ?                   
1       'Sammito, M.D.'     21 0000-0002-8346-9247 
1       'Sobolev, O.V.'     22 0000-0002-0623-3214 
1       'Stockwell, D.H.'   23 ?                   
1       'Terwilliger, T.C.' 24 0000-0001-6384-0320 
1       'Urzhumtsev, A.G.'  25 ?                   
1       'Videau, L.L.'      26 ?                   
1       'Williams, C.J.'    27 ?                   
1       'Adams, P.D.'       28 0000-0001-9333-8219 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cucumopine synthase C-terminal helical bundle domain-containing protein'                             37349.758 
2   ? ? ? ? 
2 non-polymer syn '(1~{S},3~{S})-1-(3-hydroxy-3-oxopropyl)-2,3,4,9-tetrahydropyrido[3,4-b]indole-1,3-dicarboxylic acid' 332.308   
2   ? ? ? ? 
3 non-polymer syn GLYCEROL                                                                                              92.094    
3   ? ? ? ? 
4 water       nat water                                                                                                 18.015    
236 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        KslB 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGLVPRGSHMSALPELRELIASFVSEEPPEIRRIRTGTVPDLPGSYGQYFTAWDFSNSIVRDYAMNLYQ
LTRLATDESVSVENLLTVFRTLDPIYSTFLGYNGFPVLAEYAQRVGQPAESRAELLDRLTTFTEYVNRLTAWSHHYFPWD
LGGERYRYAAEEVAAQAAEAAAASPSVDSVDSLGDPSQRIPVRLTWQPLGVQVDAEIYADLNPQLATDVLKALPFTVLQD
HAVVSGESMYAWAPLVSVAPTPVRERICDAPVGRLRFSQATGNKVIVQYGPTTETLSSPVLGKVVDSHADRLAEVGKAVW
ESTFSSKEPVWLTVERL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGLVPRGSHMSALPELRELIASFVSEEPPEIRRIRTGTVPDLPGSYGQYFTAWDFSNSIVRDYAMNLYQ
LTRLATDESVSVENLLTVFRTLDPIYSTFLGYNGFPVLAEYAQRVGQPAESRAELLDRLTTFTEYVNRLTAWSHHYFPWD
LGGERYRYAAEEVAAQAAEAAAASPSVDSVDSLGDPSQRIPVRLTWQPLGVQVDAEIYADLNPQLATDVLKALPFTVLQD
HAVVSGESMYAWAPLVSVAPTPVRERICDAPVGRLRFSQATGNKVIVQYGPTTETLSSPVLGKVVDSHADRLAEVGKAVW
ESTFSSKEPVWLTVERL
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(1~{S},3~{S})-1-(3-hydroxy-3-oxopropyl)-2,3,4,9-tetrahydropyrido[3,4-b]indole-1,3-dicarboxylic acid' A1L46 
3 GLYCEROL                                                                                              GOL   
4 water                                                                                                 HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  SER n 
1 23  ALA n 
1 24  LEU n 
1 25  PRO n 
1 26  GLU n 
1 27  LEU n 
1 28  ARG n 
1 29  GLU n 
1 30  LEU n 
1 31  ILE n 
1 32  ALA n 
1 33  SER n 
1 34  PHE n 
1 35  VAL n 
1 36  SER n 
1 37  GLU n 
1 38  GLU n 
1 39  PRO n 
1 40  PRO n 
1 41  GLU n 
1 42  ILE n 
1 43  ARG n 
1 44  ARG n 
1 45  ILE n 
1 46  ARG n 
1 47  THR n 
1 48  GLY n 
1 49  THR n 
1 50  VAL n 
1 51  PRO n 
1 52  ASP n 
1 53  LEU n 
1 54  PRO n 
1 55  GLY n 
1 56  SER n 
1 57  TYR n 
1 58  GLY n 
1 59  GLN n 
1 60  TYR n 
1 61  PHE n 
1 62  THR n 
1 63  ALA n 
1 64  TRP n 
1 65  ASP n 
1 66  PHE n 
1 67  SER n 
1 68  ASN n 
1 69  SER n 
1 70  ILE n 
1 71  VAL n 
1 72  ARG n 
1 73  ASP n 
1 74  TYR n 
1 75  ALA n 
1 76  MET n 
1 77  ASN n 
1 78  LEU n 
1 79  TYR n 
1 80  GLN n 
1 81  LEU n 
1 82  THR n 
1 83  ARG n 
1 84  LEU n 
1 85  ALA n 
1 86  THR n 
1 87  ASP n 
1 88  GLU n 
1 89  SER n 
1 90  VAL n 
1 91  SER n 
1 92  VAL n 
1 93  GLU n 
1 94  ASN n 
1 95  LEU n 
1 96  LEU n 
1 97  THR n 
1 98  VAL n 
1 99  PHE n 
1 100 ARG n 
1 101 THR n 
1 102 LEU n 
1 103 ASP n 
1 104 PRO n 
1 105 ILE n 
1 106 TYR n 
1 107 SER n 
1 108 THR n 
1 109 PHE n 
1 110 LEU n 
1 111 GLY n 
1 112 TYR n 
1 113 ASN n 
1 114 GLY n 
1 115 PHE n 
1 116 PRO n 
1 117 VAL n 
1 118 LEU n 
1 119 ALA n 
1 120 GLU n 
1 121 TYR n 
1 122 ALA n 
1 123 GLN n 
1 124 ARG n 
1 125 VAL n 
1 126 GLY n 
1 127 GLN n 
1 128 PRO n 
1 129 ALA n 
1 130 GLU n 
1 131 SER n 
1 132 ARG n 
1 133 ALA n 
1 134 GLU n 
1 135 LEU n 
1 136 LEU n 
1 137 ASP n 
1 138 ARG n 
1 139 LEU n 
1 140 THR n 
1 141 THR n 
1 142 PHE n 
1 143 THR n 
1 144 GLU n 
1 145 TYR n 
1 146 VAL n 
1 147 ASN n 
1 148 ARG n 
1 149 LEU n 
1 150 THR n 
1 151 ALA n 
1 152 TRP n 
1 153 SER n 
1 154 HIS n 
1 155 HIS n 
1 156 TYR n 
1 157 PHE n 
1 158 PRO n 
1 159 TRP n 
1 160 ASP n 
1 161 LEU n 
1 162 GLY n 
1 163 GLY n 
1 164 GLU n 
1 165 ARG n 
1 166 TYR n 
1 167 ARG n 
1 168 TYR n 
1 169 ALA n 
1 170 ALA n 
1 171 GLU n 
1 172 GLU n 
1 173 VAL n 
1 174 ALA n 
1 175 ALA n 
1 176 GLN n 
1 177 ALA n 
1 178 ALA n 
1 179 GLU n 
1 180 ALA n 
1 181 ALA n 
1 182 ALA n 
1 183 ALA n 
1 184 SER n 
1 185 PRO n 
1 186 SER n 
1 187 VAL n 
1 188 ASP n 
1 189 SER n 
1 190 VAL n 
1 191 ASP n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 ASP n 
1 196 PRO n 
1 197 SER n 
1 198 GLN n 
1 199 ARG n 
1 200 ILE n 
1 201 PRO n 
1 202 VAL n 
1 203 ARG n 
1 204 LEU n 
1 205 THR n 
1 206 TRP n 
1 207 GLN n 
1 208 PRO n 
1 209 LEU n 
1 210 GLY n 
1 211 VAL n 
1 212 GLN n 
1 213 VAL n 
1 214 ASP n 
1 215 ALA n 
1 216 GLU n 
1 217 ILE n 
1 218 TYR n 
1 219 ALA n 
1 220 ASP n 
1 221 LEU n 
1 222 ASN n 
1 223 PRO n 
1 224 GLN n 
1 225 LEU n 
1 226 ALA n 
1 227 THR n 
1 228 ASP n 
1 229 VAL n 
1 230 LEU n 
1 231 LYS n 
1 232 ALA n 
1 233 LEU n 
1 234 PRO n 
1 235 PHE n 
1 236 THR n 
1 237 VAL n 
1 238 LEU n 
1 239 GLN n 
1 240 ASP n 
1 241 HIS n 
1 242 ALA n 
1 243 VAL n 
1 244 VAL n 
1 245 SER n 
1 246 GLY n 
1 247 GLU n 
1 248 SER n 
1 249 MET n 
1 250 TYR n 
1 251 ALA n 
1 252 TRP n 
1 253 ALA n 
1 254 PRO n 
1 255 LEU n 
1 256 VAL n 
1 257 SER n 
1 258 VAL n 
1 259 ALA n 
1 260 PRO n 
1 261 THR n 
1 262 PRO n 
1 263 VAL n 
1 264 ARG n 
1 265 GLU n 
1 266 ARG n 
1 267 ILE n 
1 268 CYS n 
1 269 ASP n 
1 270 ALA n 
1 271 PRO n 
1 272 VAL n 
1 273 GLY n 
1 274 ARG n 
1 275 LEU n 
1 276 ARG n 
1 277 PHE n 
1 278 SER n 
1 279 GLN n 
1 280 ALA n 
1 281 THR n 
1 282 GLY n 
1 283 ASN n 
1 284 LYS n 
1 285 VAL n 
1 286 ILE n 
1 287 VAL n 
1 288 GLN n 
1 289 TYR n 
1 290 GLY n 
1 291 PRO n 
1 292 THR n 
1 293 THR n 
1 294 GLU n 
1 295 THR n 
1 296 LEU n 
1 297 SER n 
1 298 SER n 
1 299 PRO n 
1 300 VAL n 
1 301 LEU n 
1 302 GLY n 
1 303 LYS n 
1 304 VAL n 
1 305 VAL n 
1 306 ASP n 
1 307 SER n 
1 308 HIS n 
1 309 ALA n 
1 310 ASP n 
1 311 ARG n 
1 312 LEU n 
1 313 ALA n 
1 314 GLU n 
1 315 VAL n 
1 316 GLY n 
1 317 LYS n 
1 318 ALA n 
1 319 VAL n 
1 320 TRP n 
1 321 GLU n 
1 322 SER n 
1 323 THR n 
1 324 PHE n 
1 325 SER n 
1 326 SER n 
1 327 LYS n 
1 328 GLU n 
1 329 PRO n 
1 330 VAL n 
1 331 TRP n 
1 332 LEU n 
1 333 THR n 
1 334 VAL n 
1 335 GLU n 
1 336 ARG n 
1 337 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   337 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 KSE_70640 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      Kitasatospora 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2063 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1L46 non-polymer         . '(1~{S},3~{S})-1-(3-hydroxy-3-oxopropyl)-2,3,4,9-tetrahydropyrido[3,4-b]indole-1,3-dicarboxylic acid' 
?                               'C16 H16 N2 O6'  332.308 
ALA   'L-peptide linking' y ALANINE                                                                                               
?                               'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                                                                              
?                               'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                                                            
?                               'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                                                                       
?                               'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                                                                              
?                               'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                                                             
?                               'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                                                                       
?                               'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                                                                               
?                               'C2 H5 N O2'     75.067  
GOL   non-polymer         . GLYCEROL                                                                                              
'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS   'L-peptide linking' y HISTIDINE                                                                                             
?                               'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                                                                                                 
?                               'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                                                                            
?                               'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                                                                               
?                               'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                                                                
?                               'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                                                                            
?                               'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                                                                         
?                               'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                                                                               
?                               'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                                                                
?                               'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                                                                             
?                               'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                                                            
?                               'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                                                                              
?                               'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                                                                
?                               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -19 ?   ?   ?   A . n 
A 1 2   GLY 2   -18 ?   ?   ?   A . n 
A 1 3   SER 3   -17 ?   ?   ?   A . n 
A 1 4   SER 4   -16 ?   ?   ?   A . n 
A 1 5   HIS 5   -15 ?   ?   ?   A . n 
A 1 6   HIS 6   -14 ?   ?   ?   A . n 
A 1 7   HIS 7   -13 ?   ?   ?   A . n 
A 1 8   HIS 8   -12 ?   ?   ?   A . n 
A 1 9   HIS 9   -11 ?   ?   ?   A . n 
A 1 10  HIS 10  -10 ?   ?   ?   A . n 
A 1 11  SER 11  -9  ?   ?   ?   A . n 
A 1 12  SER 12  -8  ?   ?   ?   A . n 
A 1 13  GLY 13  -7  ?   ?   ?   A . n 
A 1 14  LEU 14  -6  ?   ?   ?   A . n 
A 1 15  VAL 15  -5  ?   ?   ?   A . n 
A 1 16  PRO 16  -4  ?   ?   ?   A . n 
A 1 17  ARG 17  -3  ?   ?   ?   A . n 
A 1 18  GLY 18  -2  ?   ?   ?   A . n 
A 1 19  SER 19  -1  ?   ?   ?   A . n 
A 1 20  HIS 20  0   ?   ?   ?   A . n 
A 1 21  MET 21  1   ?   ?   ?   A . n 
A 1 22  SER 22  2   ?   ?   ?   A . n 
A 1 23  ALA 23  3   3   ALA ALA A . n 
A 1 24  LEU 24  4   4   LEU LEU A . n 
A 1 25  PRO 25  5   5   PRO PRO A . n 
A 1 26  GLU 26  6   6   GLU GLU A . n 
A 1 27  LEU 27  7   7   LEU LEU A . n 
A 1 28  ARG 28  8   8   ARG ARG A . n 
A 1 29  GLU 29  9   9   GLU GLU A . n 
A 1 30  LEU 30  10  10  LEU LEU A . n 
A 1 31  ILE 31  11  11  ILE ILE A . n 
A 1 32  ALA 32  12  12  ALA ALA A . n 
A 1 33  SER 33  13  13  SER SER A . n 
A 1 34  PHE 34  14  14  PHE PHE A . n 
A 1 35  VAL 35  15  15  VAL VAL A . n 
A 1 36  SER 36  16  16  SER SER A . n 
A 1 37  GLU 37  17  17  GLU GLU A . n 
A 1 38  GLU 38  18  18  GLU GLU A . n 
A 1 39  PRO 39  19  19  PRO PRO A . n 
A 1 40  PRO 40  20  20  PRO PRO A . n 
A 1 41  GLU 41  21  21  GLU GLU A . n 
A 1 42  ILE 42  22  22  ILE ILE A . n 
A 1 43  ARG 43  23  23  ARG ARG A . n 
A 1 44  ARG 44  24  24  ARG ARG A . n 
A 1 45  ILE 45  25  25  ILE ILE A . n 
A 1 46  ARG 46  26  26  ARG ARG A . n 
A 1 47  THR 47  27  27  THR THR A . n 
A 1 48  GLY 48  28  28  GLY GLY A . n 
A 1 49  THR 49  29  29  THR THR A . n 
A 1 50  VAL 50  30  30  VAL VAL A . n 
A 1 51  PRO 51  31  31  PRO PRO A . n 
A 1 52  ASP 52  32  32  ASP ASP A . n 
A 1 53  LEU 53  33  33  LEU LEU A . n 
A 1 54  PRO 54  34  34  PRO PRO A . n 
A 1 55  GLY 55  35  35  GLY GLY A . n 
A 1 56  SER 56  36  36  SER SER A . n 
A 1 57  TYR 57  37  37  TYR TYR A . n 
A 1 58  GLY 58  38  38  GLY GLY A . n 
A 1 59  GLN 59  39  39  GLN GLN A . n 
A 1 60  TYR 60  40  40  TYR TYR A . n 
A 1 61  PHE 61  41  41  PHE PHE A . n 
A 1 62  THR 62  42  42  THR THR A . n 
A 1 63  ALA 63  43  43  ALA ALA A . n 
A 1 64  TRP 64  44  44  TRP TRP A . n 
A 1 65  ASP 65  45  45  ASP ASP A . n 
A 1 66  PHE 66  46  46  PHE PHE A . n 
A 1 67  SER 67  47  47  SER SER A . n 
A 1 68  ASN 68  48  48  ASN ASN A . n 
A 1 69  SER 69  49  49  SER SER A . n 
A 1 70  ILE 70  50  50  ILE ILE A . n 
A 1 71  VAL 71  51  51  VAL VAL A . n 
A 1 72  ARG 72  52  52  ARG ARG A . n 
A 1 73  ASP 73  53  53  ASP ASP A . n 
A 1 74  TYR 74  54  54  TYR TYR A . n 
A 1 75  ALA 75  55  55  ALA ALA A . n 
A 1 76  MET 76  56  56  MET MET A . n 
A 1 77  ASN 77  57  57  ASN ASN A . n 
A 1 78  LEU 78  58  58  LEU LEU A . n 
A 1 79  TYR 79  59  59  TYR TYR A . n 
A 1 80  GLN 80  60  60  GLN GLN A . n 
A 1 81  LEU 81  61  61  LEU LEU A . n 
A 1 82  THR 82  62  62  THR THR A . n 
A 1 83  ARG 83  63  63  ARG ARG A . n 
A 1 84  LEU 84  64  64  LEU LEU A . n 
A 1 85  ALA 85  65  65  ALA ALA A . n 
A 1 86  THR 86  66  66  THR THR A . n 
A 1 87  ASP 87  67  67  ASP ASP A . n 
A 1 88  GLU 88  68  68  GLU GLU A . n 
A 1 89  SER 89  69  69  SER SER A . n 
A 1 90  VAL 90  70  70  VAL VAL A . n 
A 1 91  SER 91  71  71  SER SER A . n 
A 1 92  VAL 92  72  72  VAL VAL A . n 
A 1 93  GLU 93  73  73  GLU GLU A . n 
A 1 94  ASN 94  74  74  ASN ASN A . n 
A 1 95  LEU 95  75  75  LEU LEU A . n 
A 1 96  LEU 96  76  76  LEU LEU A . n 
A 1 97  THR 97  77  77  THR THR A . n 
A 1 98  VAL 98  78  78  VAL VAL A . n 
A 1 99  PHE 99  79  79  PHE PHE A . n 
A 1 100 ARG 100 80  80  ARG ARG A . n 
A 1 101 THR 101 81  81  THR THR A . n 
A 1 102 LEU 102 82  82  LEU LEU A . n 
A 1 103 ASP 103 83  83  ASP ASP A . n 
A 1 104 PRO 104 84  84  PRO PRO A . n 
A 1 105 ILE 105 85  85  ILE ILE A . n 
A 1 106 TYR 106 86  86  TYR TYR A . n 
A 1 107 SER 107 87  87  SER SER A . n 
A 1 108 THR 108 88  88  THR THR A . n 
A 1 109 PHE 109 89  89  PHE PHE A . n 
A 1 110 LEU 110 90  90  LEU LEU A . n 
A 1 111 GLY 111 91  91  GLY GLY A . n 
A 1 112 TYR 112 92  92  TYR TYR A . n 
A 1 113 ASN 113 93  93  ASN ASN A . n 
A 1 114 GLY 114 94  94  GLY GLY A . n 
A 1 115 PHE 115 95  95  PHE PHE A . n 
A 1 116 PRO 116 96  96  PRO PRO A . n 
A 1 117 VAL 117 97  97  VAL VAL A . n 
A 1 118 LEU 118 98  98  LEU LEU A . n 
A 1 119 ALA 119 99  99  ALA ALA A . n 
A 1 120 GLU 120 100 100 GLU GLU A . n 
A 1 121 TYR 121 101 101 TYR TYR A . n 
A 1 122 ALA 122 102 102 ALA ALA A . n 
A 1 123 GLN 123 103 103 GLN GLN A . n 
A 1 124 ARG 124 104 104 ARG ARG A . n 
A 1 125 VAL 125 105 105 VAL VAL A . n 
A 1 126 GLY 126 106 106 GLY GLY A . n 
A 1 127 GLN 127 107 107 GLN GLN A . n 
A 1 128 PRO 128 108 108 PRO PRO A . n 
A 1 129 ALA 129 109 109 ALA ALA A . n 
A 1 130 GLU 130 110 110 GLU GLU A . n 
A 1 131 SER 131 111 111 SER SER A . n 
A 1 132 ARG 132 112 112 ARG ARG A . n 
A 1 133 ALA 133 113 113 ALA ALA A . n 
A 1 134 GLU 134 114 114 GLU GLU A . n 
A 1 135 LEU 135 115 115 LEU LEU A . n 
A 1 136 LEU 136 116 116 LEU LEU A . n 
A 1 137 ASP 137 117 117 ASP ASP A . n 
A 1 138 ARG 138 118 118 ARG ARG A . n 
A 1 139 LEU 139 119 119 LEU LEU A . n 
A 1 140 THR 140 120 120 THR THR A . n 
A 1 141 THR 141 121 121 THR THR A . n 
A 1 142 PHE 142 122 122 PHE PHE A . n 
A 1 143 THR 143 123 123 THR THR A . n 
A 1 144 GLU 144 124 124 GLU GLU A . n 
A 1 145 TYR 145 125 125 TYR TYR A . n 
A 1 146 VAL 146 126 126 VAL VAL A . n 
A 1 147 ASN 147 127 127 ASN ASN A . n 
A 1 148 ARG 148 128 128 ARG ARG A . n 
A 1 149 LEU 149 129 129 LEU LEU A . n 
A 1 150 THR 150 130 130 THR THR A . n 
A 1 151 ALA 151 131 131 ALA ALA A . n 
A 1 152 TRP 152 132 132 TRP TRP A . n 
A 1 153 SER 153 133 133 SER SER A . n 
A 1 154 HIS 154 134 134 HIS HIS A . n 
A 1 155 HIS 155 135 135 HIS HIS A . n 
A 1 156 TYR 156 136 136 TYR TYR A . n 
A 1 157 PHE 157 137 137 PHE PHE A . n 
A 1 158 PRO 158 138 138 PRO PRO A . n 
A 1 159 TRP 159 139 139 TRP TRP A . n 
A 1 160 ASP 160 140 140 ASP ASP A . n 
A 1 161 LEU 161 141 141 LEU LEU A . n 
A 1 162 GLY 162 142 142 GLY GLY A . n 
A 1 163 GLY 163 143 143 GLY GLY A . n 
A 1 164 GLU 164 144 144 GLU GLU A . n 
A 1 165 ARG 165 145 145 ARG ARG A . n 
A 1 166 TYR 166 146 146 TYR TYR A . n 
A 1 167 ARG 167 147 147 ARG ARG A . n 
A 1 168 TYR 168 148 148 TYR TYR A . n 
A 1 169 ALA 169 149 149 ALA ALA A . n 
A 1 170 ALA 170 150 ?   ?   ?   A . n 
A 1 171 GLU 171 151 ?   ?   ?   A . n 
A 1 172 GLU 172 152 ?   ?   ?   A . n 
A 1 173 VAL 173 153 ?   ?   ?   A . n 
A 1 174 ALA 174 154 ?   ?   ?   A . n 
A 1 175 ALA 175 155 ?   ?   ?   A . n 
A 1 176 GLN 176 156 ?   ?   ?   A . n 
A 1 177 ALA 177 157 ?   ?   ?   A . n 
A 1 178 ALA 178 158 ?   ?   ?   A . n 
A 1 179 GLU 179 159 ?   ?   ?   A . n 
A 1 180 ALA 180 160 ?   ?   ?   A . n 
A 1 181 ALA 181 161 ?   ?   ?   A . n 
A 1 182 ALA 182 162 ?   ?   ?   A . n 
A 1 183 ALA 183 163 ?   ?   ?   A . n 
A 1 184 SER 184 164 ?   ?   ?   A . n 
A 1 185 PRO 185 165 ?   ?   ?   A . n 
A 1 186 SER 186 166 ?   ?   ?   A . n 
A 1 187 VAL 187 167 ?   ?   ?   A . n 
A 1 188 ASP 188 168 ?   ?   ?   A . n 
A 1 189 SER 189 169 ?   ?   ?   A . n 
A 1 190 VAL 190 170 ?   ?   ?   A . n 
A 1 191 ASP 191 171 ?   ?   ?   A . n 
A 1 192 SER 192 172 ?   ?   ?   A . n 
A 1 193 LEU 193 173 ?   ?   ?   A . n 
A 1 194 GLY 194 174 ?   ?   ?   A . n 
A 1 195 ASP 195 175 ?   ?   ?   A . n 
A 1 196 PRO 196 176 ?   ?   ?   A . n 
A 1 197 SER 197 177 ?   ?   ?   A . n 
A 1 198 GLN 198 178 ?   ?   ?   A . n 
A 1 199 ARG 199 179 179 ARG ARG A . n 
A 1 200 ILE 200 180 180 ILE ILE A . n 
A 1 201 PRO 201 181 181 PRO PRO A . n 
A 1 202 VAL 202 182 182 VAL VAL A . n 
A 1 203 ARG 203 183 183 ARG ARG A . n 
A 1 204 LEU 204 184 184 LEU LEU A . n 
A 1 205 THR 205 185 185 THR THR A . n 
A 1 206 TRP 206 186 186 TRP TRP A . n 
A 1 207 GLN 207 187 187 GLN GLN A . n 
A 1 208 PRO 208 188 188 PRO PRO A . n 
A 1 209 LEU 209 189 189 LEU LEU A . n 
A 1 210 GLY 210 190 190 GLY GLY A . n 
A 1 211 VAL 211 191 191 VAL VAL A . n 
A 1 212 GLN 212 192 192 GLN GLN A . n 
A 1 213 VAL 213 193 193 VAL VAL A . n 
A 1 214 ASP 214 194 194 ASP ASP A . n 
A 1 215 ALA 215 195 195 ALA ALA A . n 
A 1 216 GLU 216 196 196 GLU GLU A . n 
A 1 217 ILE 217 197 197 ILE ILE A . n 
A 1 218 TYR 218 198 198 TYR TYR A . n 
A 1 219 ALA 219 199 199 ALA ALA A . n 
A 1 220 ASP 220 200 200 ASP ASP A . n 
A 1 221 LEU 221 201 201 LEU LEU A . n 
A 1 222 ASN 222 202 202 ASN ASN A . n 
A 1 223 PRO 223 203 203 PRO PRO A . n 
A 1 224 GLN 224 204 204 GLN GLN A . n 
A 1 225 LEU 225 205 205 LEU LEU A . n 
A 1 226 ALA 226 206 206 ALA ALA A . n 
A 1 227 THR 227 207 207 THR THR A . n 
A 1 228 ASP 228 208 208 ASP ASP A . n 
A 1 229 VAL 229 209 209 VAL VAL A . n 
A 1 230 LEU 230 210 210 LEU LEU A . n 
A 1 231 LYS 231 211 211 LYS LYS A . n 
A 1 232 ALA 232 212 212 ALA ALA A . n 
A 1 233 LEU 233 213 213 LEU LEU A . n 
A 1 234 PRO 234 214 214 PRO PRO A . n 
A 1 235 PHE 235 215 215 PHE PHE A . n 
A 1 236 THR 236 216 216 THR THR A . n 
A 1 237 VAL 237 217 217 VAL VAL A . n 
A 1 238 LEU 238 218 218 LEU LEU A . n 
A 1 239 GLN 239 219 219 GLN GLN A . n 
A 1 240 ASP 240 220 220 ASP ASP A . n 
A 1 241 HIS 241 221 221 HIS HIS A . n 
A 1 242 ALA 242 222 222 ALA ALA A . n 
A 1 243 VAL 243 223 223 VAL VAL A . n 
A 1 244 VAL 244 224 224 VAL VAL A . n 
A 1 245 SER 245 225 225 SER SER A . n 
A 1 246 GLY 246 226 226 GLY GLY A . n 
A 1 247 GLU 247 227 227 GLU GLU A . n 
A 1 248 SER 248 228 228 SER SER A . n 
A 1 249 MET 249 229 229 MET MET A . n 
A 1 250 TYR 250 230 230 TYR TYR A . n 
A 1 251 ALA 251 231 231 ALA ALA A . n 
A 1 252 TRP 252 232 232 TRP TRP A . n 
A 1 253 ALA 253 233 233 ALA ALA A . n 
A 1 254 PRO 254 234 234 PRO PRO A . n 
A 1 255 LEU 255 235 235 LEU LEU A . n 
A 1 256 VAL 256 236 236 VAL VAL A . n 
A 1 257 SER 257 237 237 SER SER A . n 
A 1 258 VAL 258 238 238 VAL VAL A . n 
A 1 259 ALA 259 239 239 ALA ALA A . n 
A 1 260 PRO 260 240 240 PRO PRO A . n 
A 1 261 THR 261 241 241 THR THR A . n 
A 1 262 PRO 262 242 242 PRO PRO A . n 
A 1 263 VAL 263 243 243 VAL VAL A . n 
A 1 264 ARG 264 244 244 ARG ARG A . n 
A 1 265 GLU 265 245 245 GLU GLU A . n 
A 1 266 ARG 266 246 246 ARG ARG A . n 
A 1 267 ILE 267 247 247 ILE ILE A . n 
A 1 268 CYS 268 248 248 CYS CYS A . n 
A 1 269 ASP 269 249 249 ASP ASP A . n 
A 1 270 ALA 270 250 250 ALA ALA A . n 
A 1 271 PRO 271 251 251 PRO PRO A . n 
A 1 272 VAL 272 252 252 VAL VAL A . n 
A 1 273 GLY 273 253 253 GLY GLY A . n 
A 1 274 ARG 274 254 254 ARG ARG A . n 
A 1 275 LEU 275 255 255 LEU LEU A . n 
A 1 276 ARG 276 256 256 ARG ARG A . n 
A 1 277 PHE 277 257 257 PHE PHE A . n 
A 1 278 SER 278 258 258 SER SER A . n 
A 1 279 GLN 279 259 259 GLN GLN A . n 
A 1 280 ALA 280 260 260 ALA ALA A . n 
A 1 281 THR 281 261 261 THR THR A . n 
A 1 282 GLY 282 262 262 GLY GLY A . n 
A 1 283 ASN 283 263 263 ASN ASN A . n 
A 1 284 LYS 284 264 264 LYS LYS A . n 
A 1 285 VAL 285 265 265 VAL VAL A . n 
A 1 286 ILE 286 266 266 ILE ILE A . n 
A 1 287 VAL 287 267 267 VAL VAL A . n 
A 1 288 GLN 288 268 268 GLN GLN A . n 
A 1 289 TYR 289 269 269 TYR TYR A . n 
A 1 290 GLY 290 270 270 GLY GLY A . n 
A 1 291 PRO 291 271 271 PRO PRO A . n 
A 1 292 THR 292 272 272 THR THR A . n 
A 1 293 THR 293 273 273 THR THR A . n 
A 1 294 GLU 294 274 274 GLU GLU A . n 
A 1 295 THR 295 275 275 THR THR A . n 
A 1 296 LEU 296 276 276 LEU LEU A . n 
A 1 297 SER 297 277 277 SER SER A . n 
A 1 298 SER 298 278 278 SER SER A . n 
A 1 299 PRO 299 279 279 PRO PRO A . n 
A 1 300 VAL 300 280 280 VAL VAL A . n 
A 1 301 LEU 301 281 281 LEU LEU A . n 
A 1 302 GLY 302 282 282 GLY GLY A . n 
A 1 303 LYS 303 283 283 LYS LYS A . n 
A 1 304 VAL 304 284 284 VAL VAL A . n 
A 1 305 VAL 305 285 285 VAL VAL A . n 
A 1 306 ASP 306 286 286 ASP ASP A . n 
A 1 307 SER 307 287 287 SER SER A . n 
A 1 308 HIS 308 288 288 HIS HIS A . n 
A 1 309 ALA 309 289 289 ALA ALA A . n 
A 1 310 ASP 310 290 290 ASP ASP A . n 
A 1 311 ARG 311 291 291 ARG ARG A . n 
A 1 312 LEU 312 292 292 LEU LEU A . n 
A 1 313 ALA 313 293 293 ALA ALA A . n 
A 1 314 GLU 314 294 294 GLU GLU A . n 
A 1 315 VAL 315 295 295 VAL VAL A . n 
A 1 316 GLY 316 296 296 GLY GLY A . n 
A 1 317 LYS 317 297 297 LYS LYS A . n 
A 1 318 ALA 318 298 298 ALA ALA A . n 
A 1 319 VAL 319 299 299 VAL VAL A . n 
A 1 320 TRP 320 300 300 TRP TRP A . n 
A 1 321 GLU 321 301 301 GLU GLU A . n 
A 1 322 SER 322 302 302 SER SER A . n 
A 1 323 THR 323 303 303 THR THR A . n 
A 1 324 PHE 324 304 304 PHE PHE A . n 
A 1 325 SER 325 305 305 SER SER A . n 
A 1 326 SER 326 306 306 SER SER A . n 
A 1 327 LYS 327 307 307 LYS LYS A . n 
A 1 328 GLU 328 308 308 GLU GLU A . n 
A 1 329 PRO 329 309 309 PRO PRO A . n 
A 1 330 VAL 330 310 310 VAL VAL A . n 
A 1 331 TRP 331 311 311 TRP TRP A . n 
A 1 332 LEU 332 312 312 LEU LEU A . n 
A 1 333 THR 333 313 313 THR THR A . n 
A 1 334 VAL 334 314 314 VAL VAL A . n 
A 1 335 GLU 335 315 315 GLU GLU A . n 
A 1 336 ARG 336 316 316 ARG ARG A . n 
A 1 337 LEU 337 317 317 LEU LEU A . n 
B 1 1   MET 1   -19 ?   ?   ?   B . n 
B 1 2   GLY 2   -18 ?   ?   ?   B . n 
B 1 3   SER 3   -17 ?   ?   ?   B . n 
B 1 4   SER 4   -16 ?   ?   ?   B . n 
B 1 5   HIS 5   -15 ?   ?   ?   B . n 
B 1 6   HIS 6   -14 ?   ?   ?   B . n 
B 1 7   HIS 7   -13 ?   ?   ?   B . n 
B 1 8   HIS 8   -12 ?   ?   ?   B . n 
B 1 9   HIS 9   -11 ?   ?   ?   B . n 
B 1 10  HIS 10  -10 ?   ?   ?   B . n 
B 1 11  SER 11  -9  ?   ?   ?   B . n 
B 1 12  SER 12  -8  ?   ?   ?   B . n 
B 1 13  GLY 13  -7  ?   ?   ?   B . n 
B 1 14  LEU 14  -6  ?   ?   ?   B . n 
B 1 15  VAL 15  -5  ?   ?   ?   B . n 
B 1 16  PRO 16  -4  ?   ?   ?   B . n 
B 1 17  ARG 17  -3  ?   ?   ?   B . n 
B 1 18  GLY 18  -2  ?   ?   ?   B . n 
B 1 19  SER 19  -1  ?   ?   ?   B . n 
B 1 20  HIS 20  0   ?   ?   ?   B . n 
B 1 21  MET 21  1   ?   ?   ?   B . n 
B 1 22  SER 22  2   2   SER SER B . n 
B 1 23  ALA 23  3   3   ALA ALA B . n 
B 1 24  LEU 24  4   4   LEU LEU B . n 
B 1 25  PRO 25  5   5   PRO PRO B . n 
B 1 26  GLU 26  6   6   GLU GLU B . n 
B 1 27  LEU 27  7   7   LEU LEU B . n 
B 1 28  ARG 28  8   8   ARG ARG B . n 
B 1 29  GLU 29  9   9   GLU GLU B . n 
B 1 30  LEU 30  10  10  LEU LEU B . n 
B 1 31  ILE 31  11  11  ILE ILE B . n 
B 1 32  ALA 32  12  12  ALA ALA B . n 
B 1 33  SER 33  13  13  SER SER B . n 
B 1 34  PHE 34  14  14  PHE PHE B . n 
B 1 35  VAL 35  15  15  VAL VAL B . n 
B 1 36  SER 36  16  16  SER SER B . n 
B 1 37  GLU 37  17  17  GLU GLU B . n 
B 1 38  GLU 38  18  18  GLU GLU B . n 
B 1 39  PRO 39  19  19  PRO PRO B . n 
B 1 40  PRO 40  20  20  PRO PRO B . n 
B 1 41  GLU 41  21  21  GLU GLU B . n 
B 1 42  ILE 42  22  22  ILE ILE B . n 
B 1 43  ARG 43  23  23  ARG ARG B . n 
B 1 44  ARG 44  24  24  ARG ARG B . n 
B 1 45  ILE 45  25  25  ILE ILE B . n 
B 1 46  ARG 46  26  26  ARG ARG B . n 
B 1 47  THR 47  27  27  THR THR B . n 
B 1 48  GLY 48  28  28  GLY GLY B . n 
B 1 49  THR 49  29  29  THR THR B . n 
B 1 50  VAL 50  30  30  VAL VAL B . n 
B 1 51  PRO 51  31  31  PRO PRO B . n 
B 1 52  ASP 52  32  32  ASP ASP B . n 
B 1 53  LEU 53  33  33  LEU LEU B . n 
B 1 54  PRO 54  34  ?   ?   ?   B . n 
B 1 55  GLY 55  35  35  GLY GLY B . n 
B 1 56  SER 56  36  36  SER SER B . n 
B 1 57  TYR 57  37  37  TYR TYR B . n 
B 1 58  GLY 58  38  38  GLY GLY B . n 
B 1 59  GLN 59  39  39  GLN GLN B . n 
B 1 60  TYR 60  40  40  TYR TYR B . n 
B 1 61  PHE 61  41  41  PHE PHE B . n 
B 1 62  THR 62  42  42  THR THR B . n 
B 1 63  ALA 63  43  43  ALA ALA B . n 
B 1 64  TRP 64  44  44  TRP TRP B . n 
B 1 65  ASP 65  45  45  ASP ASP B . n 
B 1 66  PHE 66  46  46  PHE PHE B . n 
B 1 67  SER 67  47  47  SER SER B . n 
B 1 68  ASN 68  48  48  ASN ASN B . n 
B 1 69  SER 69  49  49  SER SER B . n 
B 1 70  ILE 70  50  50  ILE ILE B . n 
B 1 71  VAL 71  51  51  VAL VAL B . n 
B 1 72  ARG 72  52  52  ARG ARG B . n 
B 1 73  ASP 73  53  53  ASP ASP B . n 
B 1 74  TYR 74  54  54  TYR TYR B . n 
B 1 75  ALA 75  55  55  ALA ALA B . n 
B 1 76  MET 76  56  56  MET MET B . n 
B 1 77  ASN 77  57  57  ASN ASN B . n 
B 1 78  LEU 78  58  58  LEU LEU B . n 
B 1 79  TYR 79  59  59  TYR TYR B . n 
B 1 80  GLN 80  60  60  GLN GLN B . n 
B 1 81  LEU 81  61  61  LEU LEU B . n 
B 1 82  THR 82  62  62  THR THR B . n 
B 1 83  ARG 83  63  63  ARG ARG B . n 
B 1 84  LEU 84  64  64  LEU LEU B . n 
B 1 85  ALA 85  65  65  ALA ALA B . n 
B 1 86  THR 86  66  66  THR THR B . n 
B 1 87  ASP 87  67  67  ASP ASP B . n 
B 1 88  GLU 88  68  68  GLU GLU B . n 
B 1 89  SER 89  69  69  SER SER B . n 
B 1 90  VAL 90  70  70  VAL VAL B . n 
B 1 91  SER 91  71  71  SER SER B . n 
B 1 92  VAL 92  72  72  VAL VAL B . n 
B 1 93  GLU 93  73  73  GLU GLU B . n 
B 1 94  ASN 94  74  74  ASN ASN B . n 
B 1 95  LEU 95  75  75  LEU LEU B . n 
B 1 96  LEU 96  76  76  LEU LEU B . n 
B 1 97  THR 97  77  77  THR THR B . n 
B 1 98  VAL 98  78  78  VAL VAL B . n 
B 1 99  PHE 99  79  79  PHE PHE B . n 
B 1 100 ARG 100 80  80  ARG ARG B . n 
B 1 101 THR 101 81  81  THR THR B . n 
B 1 102 LEU 102 82  82  LEU LEU B . n 
B 1 103 ASP 103 83  83  ASP ASP B . n 
B 1 104 PRO 104 84  84  PRO PRO B . n 
B 1 105 ILE 105 85  85  ILE ILE B . n 
B 1 106 TYR 106 86  86  TYR TYR B . n 
B 1 107 SER 107 87  87  SER SER B . n 
B 1 108 THR 108 88  88  THR THR B . n 
B 1 109 PHE 109 89  89  PHE PHE B . n 
B 1 110 LEU 110 90  90  LEU LEU B . n 
B 1 111 GLY 111 91  91  GLY GLY B . n 
B 1 112 TYR 112 92  92  TYR TYR B . n 
B 1 113 ASN 113 93  93  ASN ASN B . n 
B 1 114 GLY 114 94  94  GLY GLY B . n 
B 1 115 PHE 115 95  95  PHE PHE B . n 
B 1 116 PRO 116 96  96  PRO PRO B . n 
B 1 117 VAL 117 97  97  VAL VAL B . n 
B 1 118 LEU 118 98  98  LEU LEU B . n 
B 1 119 ALA 119 99  99  ALA ALA B . n 
B 1 120 GLU 120 100 100 GLU GLU B . n 
B 1 121 TYR 121 101 101 TYR TYR B . n 
B 1 122 ALA 122 102 102 ALA ALA B . n 
B 1 123 GLN 123 103 103 GLN GLN B . n 
B 1 124 ARG 124 104 104 ARG ARG B . n 
B 1 125 VAL 125 105 105 VAL VAL B . n 
B 1 126 GLY 126 106 106 GLY GLY B . n 
B 1 127 GLN 127 107 107 GLN GLN B . n 
B 1 128 PRO 128 108 108 PRO PRO B . n 
B 1 129 ALA 129 109 109 ALA ALA B . n 
B 1 130 GLU 130 110 110 GLU GLU B . n 
B 1 131 SER 131 111 111 SER SER B . n 
B 1 132 ARG 132 112 112 ARG ARG B . n 
B 1 133 ALA 133 113 113 ALA ALA B . n 
B 1 134 GLU 134 114 114 GLU GLU B . n 
B 1 135 LEU 135 115 115 LEU LEU B . n 
B 1 136 LEU 136 116 116 LEU LEU B . n 
B 1 137 ASP 137 117 117 ASP ASP B . n 
B 1 138 ARG 138 118 118 ARG ARG B . n 
B 1 139 LEU 139 119 119 LEU LEU B . n 
B 1 140 THR 140 120 120 THR THR B . n 
B 1 141 THR 141 121 121 THR THR B . n 
B 1 142 PHE 142 122 122 PHE PHE B . n 
B 1 143 THR 143 123 123 THR THR B . n 
B 1 144 GLU 144 124 124 GLU GLU B . n 
B 1 145 TYR 145 125 125 TYR TYR B . n 
B 1 146 VAL 146 126 126 VAL VAL B . n 
B 1 147 ASN 147 127 127 ASN ASN B . n 
B 1 148 ARG 148 128 128 ARG ARG B . n 
B 1 149 LEU 149 129 129 LEU LEU B . n 
B 1 150 THR 150 130 130 THR THR B . n 
B 1 151 ALA 151 131 131 ALA ALA B . n 
B 1 152 TRP 152 132 132 TRP TRP B . n 
B 1 153 SER 153 133 133 SER SER B . n 
B 1 154 HIS 154 134 134 HIS HIS B . n 
B 1 155 HIS 155 135 135 HIS HIS B . n 
B 1 156 TYR 156 136 136 TYR TYR B . n 
B 1 157 PHE 157 137 137 PHE PHE B . n 
B 1 158 PRO 158 138 138 PRO PRO B . n 
B 1 159 TRP 159 139 139 TRP TRP B . n 
B 1 160 ASP 160 140 140 ASP ASP B . n 
B 1 161 LEU 161 141 141 LEU LEU B . n 
B 1 162 GLY 162 142 142 GLY GLY B . n 
B 1 163 GLY 163 143 143 GLY GLY B . n 
B 1 164 GLU 164 144 144 GLU GLU B . n 
B 1 165 ARG 165 145 145 ARG ARG B . n 
B 1 166 TYR 166 146 146 TYR TYR B . n 
B 1 167 ARG 167 147 147 ARG ARG B . n 
B 1 168 TYR 168 148 148 TYR TYR B . n 
B 1 169 ALA 169 149 149 ALA ALA B . n 
B 1 170 ALA 170 150 ?   ?   ?   B . n 
B 1 171 GLU 171 151 ?   ?   ?   B . n 
B 1 172 GLU 172 152 ?   ?   ?   B . n 
B 1 173 VAL 173 153 ?   ?   ?   B . n 
B 1 174 ALA 174 154 ?   ?   ?   B . n 
B 1 175 ALA 175 155 ?   ?   ?   B . n 
B 1 176 GLN 176 156 ?   ?   ?   B . n 
B 1 177 ALA 177 157 ?   ?   ?   B . n 
B 1 178 ALA 178 158 ?   ?   ?   B . n 
B 1 179 GLU 179 159 ?   ?   ?   B . n 
B 1 180 ALA 180 160 ?   ?   ?   B . n 
B 1 181 ALA 181 161 ?   ?   ?   B . n 
B 1 182 ALA 182 162 ?   ?   ?   B . n 
B 1 183 ALA 183 163 ?   ?   ?   B . n 
B 1 184 SER 184 164 ?   ?   ?   B . n 
B 1 185 PRO 185 165 ?   ?   ?   B . n 
B 1 186 SER 186 166 ?   ?   ?   B . n 
B 1 187 VAL 187 167 ?   ?   ?   B . n 
B 1 188 ASP 188 168 ?   ?   ?   B . n 
B 1 189 SER 189 169 ?   ?   ?   B . n 
B 1 190 VAL 190 170 ?   ?   ?   B . n 
B 1 191 ASP 191 171 ?   ?   ?   B . n 
B 1 192 SER 192 172 ?   ?   ?   B . n 
B 1 193 LEU 193 173 ?   ?   ?   B . n 
B 1 194 GLY 194 174 ?   ?   ?   B . n 
B 1 195 ASP 195 175 ?   ?   ?   B . n 
B 1 196 PRO 196 176 ?   ?   ?   B . n 
B 1 197 SER 197 177 ?   ?   ?   B . n 
B 1 198 GLN 198 178 178 GLN GLN B . n 
B 1 199 ARG 199 179 179 ARG ARG B . n 
B 1 200 ILE 200 180 180 ILE ILE B . n 
B 1 201 PRO 201 181 181 PRO PRO B . n 
B 1 202 VAL 202 182 182 VAL VAL B . n 
B 1 203 ARG 203 183 183 ARG ARG B . n 
B 1 204 LEU 204 184 184 LEU LEU B . n 
B 1 205 THR 205 185 185 THR THR B . n 
B 1 206 TRP 206 186 186 TRP TRP B . n 
B 1 207 GLN 207 187 187 GLN GLN B . n 
B 1 208 PRO 208 188 188 PRO PRO B . n 
B 1 209 LEU 209 189 189 LEU LEU B . n 
B 1 210 GLY 210 190 190 GLY GLY B . n 
B 1 211 VAL 211 191 191 VAL VAL B . n 
B 1 212 GLN 212 192 192 GLN GLN B . n 
B 1 213 VAL 213 193 193 VAL VAL B . n 
B 1 214 ASP 214 194 194 ASP ASP B . n 
B 1 215 ALA 215 195 195 ALA ALA B . n 
B 1 216 GLU 216 196 196 GLU GLU B . n 
B 1 217 ILE 217 197 197 ILE ILE B . n 
B 1 218 TYR 218 198 198 TYR TYR B . n 
B 1 219 ALA 219 199 199 ALA ALA B . n 
B 1 220 ASP 220 200 200 ASP ASP B . n 
B 1 221 LEU 221 201 201 LEU LEU B . n 
B 1 222 ASN 222 202 202 ASN ASN B . n 
B 1 223 PRO 223 203 203 PRO PRO B . n 
B 1 224 GLN 224 204 204 GLN GLN B . n 
B 1 225 LEU 225 205 205 LEU LEU B . n 
B 1 226 ALA 226 206 206 ALA ALA B . n 
B 1 227 THR 227 207 207 THR THR B . n 
B 1 228 ASP 228 208 208 ASP ASP B . n 
B 1 229 VAL 229 209 209 VAL VAL B . n 
B 1 230 LEU 230 210 210 LEU LEU B . n 
B 1 231 LYS 231 211 211 LYS LYS B . n 
B 1 232 ALA 232 212 212 ALA ALA B . n 
B 1 233 LEU 233 213 213 LEU LEU B . n 
B 1 234 PRO 234 214 214 PRO PRO B . n 
B 1 235 PHE 235 215 215 PHE PHE B . n 
B 1 236 THR 236 216 216 THR THR B . n 
B 1 237 VAL 237 217 217 VAL VAL B . n 
B 1 238 LEU 238 218 218 LEU LEU B . n 
B 1 239 GLN 239 219 219 GLN GLN B . n 
B 1 240 ASP 240 220 220 ASP ASP B . n 
B 1 241 HIS 241 221 221 HIS HIS B . n 
B 1 242 ALA 242 222 222 ALA ALA B . n 
B 1 243 VAL 243 223 223 VAL VAL B . n 
B 1 244 VAL 244 224 224 VAL VAL B . n 
B 1 245 SER 245 225 225 SER SER B . n 
B 1 246 GLY 246 226 226 GLY GLY B . n 
B 1 247 GLU 247 227 227 GLU GLU B . n 
B 1 248 SER 248 228 228 SER SER B . n 
B 1 249 MET 249 229 229 MET MET B . n 
B 1 250 TYR 250 230 230 TYR TYR B . n 
B 1 251 ALA 251 231 231 ALA ALA B . n 
B 1 252 TRP 252 232 232 TRP TRP B . n 
B 1 253 ALA 253 233 233 ALA ALA B . n 
B 1 254 PRO 254 234 234 PRO PRO B . n 
B 1 255 LEU 255 235 235 LEU LEU B . n 
B 1 256 VAL 256 236 236 VAL VAL B . n 
B 1 257 SER 257 237 237 SER SER B . n 
B 1 258 VAL 258 238 238 VAL VAL B . n 
B 1 259 ALA 259 239 239 ALA ALA B . n 
B 1 260 PRO 260 240 240 PRO PRO B . n 
B 1 261 THR 261 241 241 THR THR B . n 
B 1 262 PRO 262 242 242 PRO PRO B . n 
B 1 263 VAL 263 243 243 VAL VAL B . n 
B 1 264 ARG 264 244 244 ARG ARG B . n 
B 1 265 GLU 265 245 245 GLU GLU B . n 
B 1 266 ARG 266 246 246 ARG ARG B . n 
B 1 267 ILE 267 247 247 ILE ILE B . n 
B 1 268 CYS 268 248 248 CYS CYS B . n 
B 1 269 ASP 269 249 249 ASP ASP B . n 
B 1 270 ALA 270 250 250 ALA ALA B . n 
B 1 271 PRO 271 251 251 PRO PRO B . n 
B 1 272 VAL 272 252 252 VAL VAL B . n 
B 1 273 GLY 273 253 253 GLY GLY B . n 
B 1 274 ARG 274 254 254 ARG ARG B . n 
B 1 275 LEU 275 255 255 LEU LEU B . n 
B 1 276 ARG 276 256 256 ARG ARG B . n 
B 1 277 PHE 277 257 257 PHE PHE B . n 
B 1 278 SER 278 258 258 SER SER B . n 
B 1 279 GLN 279 259 259 GLN GLN B . n 
B 1 280 ALA 280 260 260 ALA ALA B . n 
B 1 281 THR 281 261 261 THR THR B . n 
B 1 282 GLY 282 262 262 GLY GLY B . n 
B 1 283 ASN 283 263 263 ASN ASN B . n 
B 1 284 LYS 284 264 264 LYS LYS B . n 
B 1 285 VAL 285 265 265 VAL VAL B . n 
B 1 286 ILE 286 266 266 ILE ILE B . n 
B 1 287 VAL 287 267 267 VAL VAL B . n 
B 1 288 GLN 288 268 268 GLN GLN B . n 
B 1 289 TYR 289 269 269 TYR TYR B . n 
B 1 290 GLY 290 270 270 GLY GLY B . n 
B 1 291 PRO 291 271 271 PRO PRO B . n 
B 1 292 THR 292 272 272 THR THR B . n 
B 1 293 THR 293 273 273 THR THR B . n 
B 1 294 GLU 294 274 274 GLU GLU B . n 
B 1 295 THR 295 275 275 THR THR B . n 
B 1 296 LEU 296 276 276 LEU LEU B . n 
B 1 297 SER 297 277 277 SER SER B . n 
B 1 298 SER 298 278 278 SER SER B . n 
B 1 299 PRO 299 279 279 PRO PRO B . n 
B 1 300 VAL 300 280 280 VAL VAL B . n 
B 1 301 LEU 301 281 281 LEU LEU B . n 
B 1 302 GLY 302 282 282 GLY GLY B . n 
B 1 303 LYS 303 283 283 LYS LYS B . n 
B 1 304 VAL 304 284 284 VAL VAL B . n 
B 1 305 VAL 305 285 285 VAL VAL B . n 
B 1 306 ASP 306 286 286 ASP ASP B . n 
B 1 307 SER 307 287 287 SER SER B . n 
B 1 308 HIS 308 288 288 HIS HIS B . n 
B 1 309 ALA 309 289 289 ALA ALA B . n 
B 1 310 ASP 310 290 290 ASP ASP B . n 
B 1 311 ARG 311 291 291 ARG ARG B . n 
B 1 312 LEU 312 292 292 LEU LEU B . n 
B 1 313 ALA 313 293 293 ALA ALA B . n 
B 1 314 GLU 314 294 294 GLU GLU B . n 
B 1 315 VAL 315 295 295 VAL VAL B . n 
B 1 316 GLY 316 296 296 GLY GLY B . n 
B 1 317 LYS 317 297 297 LYS LYS B . n 
B 1 318 ALA 318 298 298 ALA ALA B . n 
B 1 319 VAL 319 299 299 VAL VAL B . n 
B 1 320 TRP 320 300 300 TRP TRP B . n 
B 1 321 GLU 321 301 301 GLU GLU B . n 
B 1 322 SER 322 302 302 SER SER B . n 
B 1 323 THR 323 303 303 THR THR B . n 
B 1 324 PHE 324 304 304 PHE PHE B . n 
B 1 325 SER 325 305 305 SER SER B . n 
B 1 326 SER 326 306 306 SER SER B . n 
B 1 327 LYS 327 307 307 LYS LYS B . n 
B 1 328 GLU 328 308 308 GLU GLU B . n 
B 1 329 PRO 329 309 309 PRO PRO B . n 
B 1 330 VAL 330 310 310 VAL VAL B . n 
B 1 331 TRP 331 311 311 TRP TRP B . n 
B 1 332 LEU 332 312 312 LEU LEU B . n 
B 1 333 THR 333 313 313 THR THR B . n 
B 1 334 VAL 334 314 314 VAL VAL B . n 
B 1 335 GLU 335 315 315 GLU GLU B . n 
B 1 336 ARG 336 316 316 ARG ARG B . n 
B 1 337 LEU 337 317 317 LEU LEU B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1L46 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1L46 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 A1L46 1   401 401 A1L46 UNL A . 
D 3 GOL   1   402 402 GOL   GOL A . 
E 3 GOL   1   403 403 GOL   GOL A . 
F 2 A1L46 1   401 401 A1L46 UNL B . 
G 3 GOL   1   402 402 GOL   GOL B . 
H 4 HOH   1   501 34  HOH   HOH A . 
H 4 HOH   2   502 11  HOH   HOH A . 
H 4 HOH   3   503 233 HOH   HOH A . 
H 4 HOH   4   504 218 HOH   HOH A . 
H 4 HOH   5   505 91  HOH   HOH A . 
H 4 HOH   6   506 177 HOH   HOH A . 
H 4 HOH   7   507 36  HOH   HOH A . 
H 4 HOH   8   508 155 HOH   HOH A . 
H 4 HOH   9   509 63  HOH   HOH A . 
H 4 HOH   10  510 229 HOH   HOH A . 
H 4 HOH   11  511 106 HOH   HOH A . 
H 4 HOH   12  512 71  HOH   HOH A . 
H 4 HOH   13  513 212 HOH   HOH A . 
H 4 HOH   14  514 252 HOH   HOH A . 
H 4 HOH   15  515 149 HOH   HOH A . 
H 4 HOH   16  516 87  HOH   HOH A . 
H 4 HOH   17  517 128 HOH   HOH A . 
H 4 HOH   18  518 17  HOH   HOH A . 
H 4 HOH   19  519 90  HOH   HOH A . 
H 4 HOH   20  520 21  HOH   HOH A . 
H 4 HOH   21  521 140 HOH   HOH A . 
H 4 HOH   22  522 55  HOH   HOH A . 
H 4 HOH   23  523 125 HOH   HOH A . 
H 4 HOH   24  524 59  HOH   HOH A . 
H 4 HOH   25  525 54  HOH   HOH A . 
H 4 HOH   26  526 192 HOH   HOH A . 
H 4 HOH   27  527 164 HOH   HOH A . 
H 4 HOH   28  528 49  HOH   HOH A . 
H 4 HOH   29  529 52  HOH   HOH A . 
H 4 HOH   30  530 20  HOH   HOH A . 
H 4 HOH   31  531 211 HOH   HOH A . 
H 4 HOH   32  532 51  HOH   HOH A . 
H 4 HOH   33  533 67  HOH   HOH A . 
H 4 HOH   34  534 104 HOH   HOH A . 
H 4 HOH   35  535 75  HOH   HOH A . 
H 4 HOH   36  536 190 HOH   HOH A . 
H 4 HOH   37  537 26  HOH   HOH A . 
H 4 HOH   38  538 50  HOH   HOH A . 
H 4 HOH   39  539 118 HOH   HOH A . 
H 4 HOH   40  540 182 HOH   HOH A . 
H 4 HOH   41  541 46  HOH   HOH A . 
H 4 HOH   42  542 40  HOH   HOH A . 
H 4 HOH   43  543 58  HOH   HOH A . 
H 4 HOH   44  544 2   HOH   HOH A . 
H 4 HOH   45  545 88  HOH   HOH A . 
H 4 HOH   46  546 126 HOH   HOH A . 
H 4 HOH   47  547 19  HOH   HOH A . 
H 4 HOH   48  548 61  HOH   HOH A . 
H 4 HOH   49  549 143 HOH   HOH A . 
H 4 HOH   50  550 48  HOH   HOH A . 
H 4 HOH   51  551 198 HOH   HOH A . 
H 4 HOH   52  552 102 HOH   HOH A . 
H 4 HOH   53  553 14  HOH   HOH A . 
H 4 HOH   54  554 159 HOH   HOH A . 
H 4 HOH   55  555 4   HOH   HOH A . 
H 4 HOH   56  556 222 HOH   HOH A . 
H 4 HOH   57  557 98  HOH   HOH A . 
H 4 HOH   58  558 141 HOH   HOH A . 
H 4 HOH   59  559 9   HOH   HOH A . 
H 4 HOH   60  560 197 HOH   HOH A . 
H 4 HOH   61  561 248 HOH   HOH A . 
H 4 HOH   62  562 153 HOH   HOH A . 
H 4 HOH   63  563 180 HOH   HOH A . 
H 4 HOH   64  564 178 HOH   HOH A . 
H 4 HOH   65  565 131 HOH   HOH A . 
H 4 HOH   66  566 84  HOH   HOH A . 
H 4 HOH   67  567 81  HOH   HOH A . 
H 4 HOH   68  568 3   HOH   HOH A . 
H 4 HOH   69  569 132 HOH   HOH A . 
H 4 HOH   70  570 22  HOH   HOH A . 
H 4 HOH   71  571 5   HOH   HOH A . 
H 4 HOH   72  572 6   HOH   HOH A . 
H 4 HOH   73  573 23  HOH   HOH A . 
H 4 HOH   74  574 162 HOH   HOH A . 
H 4 HOH   75  575 216 HOH   HOH A . 
H 4 HOH   76  576 151 HOH   HOH A . 
H 4 HOH   77  577 134 HOH   HOH A . 
H 4 HOH   78  578 236 HOH   HOH A . 
H 4 HOH   79  579 246 HOH   HOH A . 
H 4 HOH   80  580 199 HOH   HOH A . 
H 4 HOH   81  581 16  HOH   HOH A . 
H 4 HOH   82  582 47  HOH   HOH A . 
H 4 HOH   83  583 133 HOH   HOH A . 
H 4 HOH   84  584 60  HOH   HOH A . 
H 4 HOH   85  585 129 HOH   HOH A . 
H 4 HOH   86  586 100 HOH   HOH A . 
H 4 HOH   87  587 105 HOH   HOH A . 
H 4 HOH   88  588 29  HOH   HOH A . 
H 4 HOH   89  589 65  HOH   HOH A . 
H 4 HOH   90  590 223 HOH   HOH A . 
H 4 HOH   91  591 78  HOH   HOH A . 
H 4 HOH   92  592 172 HOH   HOH A . 
H 4 HOH   93  593 214 HOH   HOH A . 
H 4 HOH   94  594 206 HOH   HOH A . 
H 4 HOH   95  595 150 HOH   HOH A . 
H 4 HOH   96  596 174 HOH   HOH A . 
H 4 HOH   97  597 188 HOH   HOH A . 
H 4 HOH   98  598 93  HOH   HOH A . 
H 4 HOH   99  599 99  HOH   HOH A . 
H 4 HOH   100 600 114 HOH   HOH A . 
H 4 HOH   101 601 156 HOH   HOH A . 
H 4 HOH   102 602 249 HOH   HOH A . 
H 4 HOH   103 603 196 HOH   HOH A . 
H 4 HOH   104 604 175 HOH   HOH A . 
H 4 HOH   105 605 219 HOH   HOH A . 
H 4 HOH   106 606 123 HOH   HOH A . 
H 4 HOH   107 607 217 HOH   HOH A . 
H 4 HOH   108 608 193 HOH   HOH A . 
H 4 HOH   109 609 72  HOH   HOH A . 
H 4 HOH   110 610 135 HOH   HOH A . 
H 4 HOH   111 611 111 HOH   HOH A . 
H 4 HOH   112 612 56  HOH   HOH A . 
H 4 HOH   113 613 173 HOH   HOH A . 
H 4 HOH   114 614 121 HOH   HOH A . 
H 4 HOH   115 615 238 HOH   HOH A . 
H 4 HOH   116 616 245 HOH   HOH A . 
I 4 HOH   1   501 68  HOH   HOH B . 
I 4 HOH   2   502 32  HOH   HOH B . 
I 4 HOH   3   503 247 HOH   HOH B . 
I 4 HOH   4   504 144 HOH   HOH B . 
I 4 HOH   5   505 207 HOH   HOH B . 
I 4 HOH   6   506 45  HOH   HOH B . 
I 4 HOH   7   507 147 HOH   HOH B . 
I 4 HOH   8   508 183 HOH   HOH B . 
I 4 HOH   9   509 171 HOH   HOH B . 
I 4 HOH   10  510 145 HOH   HOH B . 
I 4 HOH   11  511 239 HOH   HOH B . 
I 4 HOH   12  512 115 HOH   HOH B . 
I 4 HOH   13  513 232 HOH   HOH B . 
I 4 HOH   14  514 120 HOH   HOH B . 
I 4 HOH   15  515 77  HOH   HOH B . 
I 4 HOH   16  516 69  HOH   HOH B . 
I 4 HOH   17  517 227 HOH   HOH B . 
I 4 HOH   18  518 110 HOH   HOH B . 
I 4 HOH   19  519 127 HOH   HOH B . 
I 4 HOH   20  520 31  HOH   HOH B . 
I 4 HOH   21  521 37  HOH   HOH B . 
I 4 HOH   22  522 42  HOH   HOH B . 
I 4 HOH   23  523 136 HOH   HOH B . 
I 4 HOH   24  524 101 HOH   HOH B . 
I 4 HOH   25  525 8   HOH   HOH B . 
I 4 HOH   26  526 30  HOH   HOH B . 
I 4 HOH   27  527 70  HOH   HOH B . 
I 4 HOH   28  528 28  HOH   HOH B . 
I 4 HOH   29  529 157 HOH   HOH B . 
I 4 HOH   30  530 142 HOH   HOH B . 
I 4 HOH   31  531 57  HOH   HOH B . 
I 4 HOH   32  532 94  HOH   HOH B . 
I 4 HOH   33  533 7   HOH   HOH B . 
I 4 HOH   34  534 13  HOH   HOH B . 
I 4 HOH   35  535 235 HOH   HOH B . 
I 4 HOH   36  536 97  HOH   HOH B . 
I 4 HOH   37  537 1   HOH   HOH B . 
I 4 HOH   38  538 41  HOH   HOH B . 
I 4 HOH   39  539 139 HOH   HOH B . 
I 4 HOH   40  540 119 HOH   HOH B . 
I 4 HOH   41  541 181 HOH   HOH B . 
I 4 HOH   42  542 116 HOH   HOH B . 
I 4 HOH   43  543 203 HOH   HOH B . 
I 4 HOH   44  544 76  HOH   HOH B . 
I 4 HOH   45  545 89  HOH   HOH B . 
I 4 HOH   46  546 234 HOH   HOH B . 
I 4 HOH   47  547 231 HOH   HOH B . 
I 4 HOH   48  548 53  HOH   HOH B . 
I 4 HOH   49  549 10  HOH   HOH B . 
I 4 HOH   50  550 86  HOH   HOH B . 
I 4 HOH   51  551 243 HOH   HOH B . 
I 4 HOH   52  552 244 HOH   HOH B . 
I 4 HOH   53  553 240 HOH   HOH B . 
I 4 HOH   54  554 201 HOH   HOH B . 
I 4 HOH   55  555 38  HOH   HOH B . 
I 4 HOH   56  556 80  HOH   HOH B . 
I 4 HOH   57  557 18  HOH   HOH B . 
I 4 HOH   58  558 12  HOH   HOH B . 
I 4 HOH   59  559 82  HOH   HOH B . 
I 4 HOH   60  560 35  HOH   HOH B . 
I 4 HOH   61  561 209 HOH   HOH B . 
I 4 HOH   62  562 208 HOH   HOH B . 
I 4 HOH   63  563 226 HOH   HOH B . 
I 4 HOH   64  564 138 HOH   HOH B . 
I 4 HOH   65  565 185 HOH   HOH B . 
I 4 HOH   66  566 179 HOH   HOH B . 
I 4 HOH   67  567 107 HOH   HOH B . 
I 4 HOH   68  568 130 HOH   HOH B . 
I 4 HOH   69  569 95  HOH   HOH B . 
I 4 HOH   70  570 146 HOH   HOH B . 
I 4 HOH   71  571 24  HOH   HOH B . 
I 4 HOH   72  572 202 HOH   HOH B . 
I 4 HOH   73  573 242 HOH   HOH B . 
I 4 HOH   74  574 113 HOH   HOH B . 
I 4 HOH   75  575 79  HOH   HOH B . 
I 4 HOH   76  576 160 HOH   HOH B . 
I 4 HOH   77  577 27  HOH   HOH B . 
I 4 HOH   78  578 33  HOH   HOH B . 
I 4 HOH   79  579 189 HOH   HOH B . 
I 4 HOH   80  580 96  HOH   HOH B . 
I 4 HOH   81  581 137 HOH   HOH B . 
I 4 HOH   82  582 62  HOH   HOH B . 
I 4 HOH   83  583 186 HOH   HOH B . 
I 4 HOH   84  584 83  HOH   HOH B . 
I 4 HOH   85  585 167 HOH   HOH B . 
I 4 HOH   86  586 122 HOH   HOH B . 
I 4 HOH   87  587 200 HOH   HOH B . 
I 4 HOH   88  588 112 HOH   HOH B . 
I 4 HOH   89  589 73  HOH   HOH B . 
I 4 HOH   90  590 44  HOH   HOH B . 
I 4 HOH   91  591 64  HOH   HOH B . 
I 4 HOH   92  592 85  HOH   HOH B . 
I 4 HOH   93  593 221 HOH   HOH B . 
I 4 HOH   94  594 213 HOH   HOH B . 
I 4 HOH   95  595 148 HOH   HOH B . 
I 4 HOH   96  596 109 HOH   HOH B . 
I 4 HOH   97  597 205 HOH   HOH B . 
I 4 HOH   98  598 92  HOH   HOH B . 
I 4 HOH   99  599 161 HOH   HOH B . 
I 4 HOH   100 600 103 HOH   HOH B . 
I 4 HOH   101 601 187 HOH   HOH B . 
I 4 HOH   102 602 15  HOH   HOH B . 
I 4 HOH   103 603 194 HOH   HOH B . 
I 4 HOH   104 604 184 HOH   HOH B . 
I 4 HOH   105 605 241 HOH   HOH B . 
I 4 HOH   106 606 74  HOH   HOH B . 
I 4 HOH   107 607 195 HOH   HOH B . 
I 4 HOH   108 608 237 HOH   HOH B . 
I 4 HOH   109 609 204 HOH   HOH B . 
I 4 HOH   110 610 158 HOH   HOH B . 
I 4 HOH   111 611 66  HOH   HOH B . 
I 4 HOH   112 612 228 HOH   HOH B . 
I 4 HOH   113 613 170 HOH   HOH B . 
I 4 HOH   114 614 250 HOH   HOH B . 
I 4 HOH   115 615 191 HOH   HOH B . 
I 4 HOH   116 616 108 HOH   HOH B . 
I 4 HOH   117 617 154 HOH   HOH B . 
I 4 HOH   118 618 251 HOH   HOH B . 
I 4 HOH   119 619 225 HOH   HOH B . 
I 4 HOH   120 620 215 HOH   HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 144 ? CG  ? A GLU 164 CG  
2  1 Y 1 A GLU 144 ? CD  ? A GLU 164 CD  
3  1 Y 1 A GLU 144 ? OE1 ? A GLU 164 OE1 
4  1 Y 1 A GLU 144 ? OE2 ? A GLU 164 OE2 
5  1 Y 1 A ARG 147 ? CG  ? A ARG 167 CG  
6  1 Y 1 A ARG 147 ? CD  ? A ARG 167 CD  
7  1 Y 1 A ARG 147 ? NE  ? A ARG 167 NE  
8  1 Y 1 A ARG 147 ? CZ  ? A ARG 167 CZ  
9  1 Y 1 A ARG 147 ? NH1 ? A ARG 167 NH1 
10 1 Y 1 A ARG 147 ? NH2 ? A ARG 167 NH2 
11 1 Y 1 A GLU 308 ? CG  ? A GLU 328 CG  
12 1 Y 1 A GLU 308 ? CD  ? A GLU 328 CD  
13 1 Y 1 A GLU 308 ? OE1 ? A GLU 328 OE1 
14 1 Y 1 A GLU 308 ? OE2 ? A GLU 328 OE2 
15 1 Y 1 B LEU 33  ? CG  ? B LEU 53  CG  
16 1 Y 1 B LEU 33  ? CD1 ? B LEU 53  CD1 
17 1 Y 1 B LEU 33  ? CD2 ? B LEU 53  CD2 
18 1 Y 1 B GLU 110 ? CG  ? B GLU 130 CG  
19 1 Y 1 B GLU 110 ? CD  ? B GLU 130 CD  
20 1 Y 1 B GLU 110 ? OE1 ? B GLU 130 OE1 
21 1 Y 1 B GLU 110 ? OE2 ? B GLU 130 OE2 
22 1 Y 1 B ARG 183 ? CG  ? B ARG 203 CG  
23 1 Y 1 B ARG 183 ? CD  ? B ARG 203 CD  
24 1 Y 1 B ARG 183 ? NE  ? B ARG 203 NE  
25 1 Y 1 B ARG 183 ? CZ  ? B ARG 203 CZ  
26 1 Y 1 B ARG 183 ? NH1 ? B ARG 203 NH1 
27 1 Y 1 B ARG 183 ? NH2 ? B ARG 203 NH2 
28 1 Y 1 B LYS 211 ? CG  ? B LYS 231 CG  
29 1 Y 1 B LYS 211 ? CD  ? B LYS 231 CD  
30 1 Y 1 B LYS 211 ? CE  ? B LYS 231 CE  
31 1 Y 1 B LYS 211 ? NZ  ? B LYS 231 NZ  
32 1 Y 1 B ILE 247 ? CG1 ? B ILE 267 CG1 
33 1 Y 1 B ILE 247 ? CG2 ? B ILE 267 CG2 
34 1 Y 1 B ILE 247 ? CD1 ? B ILE 267 CD1 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   109.321 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9K0A 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     57.077 
_cell.length_a_esd                 ? 
_cell.length_b                     82.992 
_cell.length_b_esd                 ? 
_cell.length_c                     64.501 
_cell.length_c_esd                 ? 
_cell.volume                       288329.084 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9K0A 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9K0A 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.93 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          36.27 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM calcium acetate, 100 mM cacodylate pH 6.0, and 12% PEG8000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-05-30 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.1 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PHOTON FACTORY BEAMLINE BL-1A' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.1 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL-1A 
_diffrn_source.pdbx_synchrotron_site       'Photon Factory' 
# 
_reflns.B_iso_Wilson_estimate                          24.82 
_reflns.entry_id                                       9K0A 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.17 
_reflns.d_resolution_low                               49.22 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     30086 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.996 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.092 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.17 
_reflns_shell.d_res_low                                     2.24 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.2 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2603 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               4.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.765 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.482 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               29.23 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9K0A 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.17 
_refine.ls_d_res_low                             49.22 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     28558 
_refine.ls_number_reflns_R_free                  1887 
_refine.ls_number_reflns_R_work                  26671 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    94.76 
_refine.ls_percent_reflns_R_free                 6.61 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2030 
_refine.ls_R_factor_R_free                       0.2490 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1997 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          0.00 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.4685 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2647 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.17 
_refine_hist.d_res_low                        49.22 
_refine_hist.number_atoms_solvent             236 
_refine_hist.number_atoms_total               4836 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4534 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         66 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0023 ? 4730 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5560 ? 6479 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0405 ? 728  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0042 ? 830  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 5.4841 ? 650  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.17 2.23  . . 135 1897 87.62 . . . . 0.2345 . . . . . . . . . . . 0.2906 
'X-RAY DIFFRACTION' 2.23 2.29  . . 132 1923 89.27 . . . . 0.2330 . . . . . . . . . . . 0.3070 
'X-RAY DIFFRACTION' 2.29 2.37  . . 135 1928 89.73 . . . . 0.2259 . . . . . . . . . . . 0.2851 
'X-RAY DIFFRACTION' 2.37 2.45  . . 141 1963 91.80 . . . . 0.2226 . . . . . . . . . . . 0.2657 
'X-RAY DIFFRACTION' 2.45 2.55  . . 146 2013 93.75 . . . . 0.2196 . . . . . . . . . . . 0.2769 
'X-RAY DIFFRACTION' 2.55 2.67  . . 145 2063 95.21 . . . . 0.2209 . . . . . . . . . . . 0.2843 
'X-RAY DIFFRACTION' 2.67 2.81  . . 145 2059 95.41 . . . . 0.2149 . . . . . . . . . . . 0.3148 
'X-RAY DIFFRACTION' 2.81 2.98  . . 148 2088 96.67 . . . . 0.2272 . . . . . . . . . . . 0.2831 
'X-RAY DIFFRACTION' 2.98 3.21  . . 149 2141 98.20 . . . . 0.2045 . . . . . . . . . . . 0.2426 
'X-RAY DIFFRACTION' 3.21 3.54  . . 148 2110 97.75 . . . . 0.1964 . . . . . . . . . . . 0.2491 
'X-RAY DIFFRACTION' 3.54 4.05  . . 154 2164 99.06 . . . . 0.1807 . . . . . . . . . . . 0.2111 
'X-RAY DIFFRACTION' 4.05 5.10  . . 153 2133 98.79 . . . . 0.1661 . . . . . . . . . . . 0.1983 
'X-RAY DIFFRACTION' 5.10 49.22 . . 156 2189 98.49 . . . . 0.1891 . . . . . . . . . . . 0.2418 
# 
_struct.entry_id                     9K0A 
_struct.title                        'Structure of Pictet-Spenglerases KslB in complex with product' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9K0A 
_struct_keywords.text            'Pictet-Spenglerases, Kitasetalic acid, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 2 ? 
G N N 3 ? 
H N N 4 ? 
I N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    E4NIM4_KITSK 
_struct_ref.pdbx_db_accession          E4NIM4 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSALPELRELIASFVSEEPPEIRRIRTGTVPDLPGSYGQYFTAWDFSNSIVRDYAMNLYQLTRLATDESVSVENLLTVFR
TLDPIYSTFLGYNGFPVLAEYAQRVGQPAESRAELLDRLTTFTEYVNRLTAWSHHYFPWDLGGERYRYAAEEVAAQAAEA
AAASPSVDSVDSLGDPSQRIPVRLTWQPLGVQVDAEIYADLNPQLATDVLKALPFTVLQDHAVVSGESMYAWAPLVSVAP
TPVRERICDAPVGRLRFSQATGNKVIVQYGPTTETLSSPVLGKVVDSHADRLAEVGKAVWESTFSSKEPVWLTVERL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9K0A A 21 ? 337 ? E4NIM4 1 ? 317 ? 1 317 
2 1 9K0A B 21 ? 337 ? E4NIM4 1 ? 317 ? 1 317 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9K0A MET A 1  ? UNP E4NIM4 ? ? 'initiating methionine' -19 1  
1 9K0A GLY A 2  ? UNP E4NIM4 ? ? 'expression tag'        -18 2  
1 9K0A SER A 3  ? UNP E4NIM4 ? ? 'expression tag'        -17 3  
1 9K0A SER A 4  ? UNP E4NIM4 ? ? 'expression tag'        -16 4  
1 9K0A HIS A 5  ? UNP E4NIM4 ? ? 'expression tag'        -15 5  
1 9K0A HIS A 6  ? UNP E4NIM4 ? ? 'expression tag'        -14 6  
1 9K0A HIS A 7  ? UNP E4NIM4 ? ? 'expression tag'        -13 7  
1 9K0A HIS A 8  ? UNP E4NIM4 ? ? 'expression tag'        -12 8  
1 9K0A HIS A 9  ? UNP E4NIM4 ? ? 'expression tag'        -11 9  
1 9K0A HIS A 10 ? UNP E4NIM4 ? ? 'expression tag'        -10 10 
1 9K0A SER A 11 ? UNP E4NIM4 ? ? 'expression tag'        -9  11 
1 9K0A SER A 12 ? UNP E4NIM4 ? ? 'expression tag'        -8  12 
1 9K0A GLY A 13 ? UNP E4NIM4 ? ? 'expression tag'        -7  13 
1 9K0A LEU A 14 ? UNP E4NIM4 ? ? 'expression tag'        -6  14 
1 9K0A VAL A 15 ? UNP E4NIM4 ? ? 'expression tag'        -5  15 
1 9K0A PRO A 16 ? UNP E4NIM4 ? ? 'expression tag'        -4  16 
1 9K0A ARG A 17 ? UNP E4NIM4 ? ? 'expression tag'        -3  17 
1 9K0A GLY A 18 ? UNP E4NIM4 ? ? 'expression tag'        -2  18 
1 9K0A SER A 19 ? UNP E4NIM4 ? ? 'expression tag'        -1  19 
1 9K0A HIS A 20 ? UNP E4NIM4 ? ? 'expression tag'        0   20 
2 9K0A MET B 1  ? UNP E4NIM4 ? ? 'initiating methionine' -19 21 
2 9K0A GLY B 2  ? UNP E4NIM4 ? ? 'expression tag'        -18 22 
2 9K0A SER B 3  ? UNP E4NIM4 ? ? 'expression tag'        -17 23 
2 9K0A SER B 4  ? UNP E4NIM4 ? ? 'expression tag'        -16 24 
2 9K0A HIS B 5  ? UNP E4NIM4 ? ? 'expression tag'        -15 25 
2 9K0A HIS B 6  ? UNP E4NIM4 ? ? 'expression tag'        -14 26 
2 9K0A HIS B 7  ? UNP E4NIM4 ? ? 'expression tag'        -13 27 
2 9K0A HIS B 8  ? UNP E4NIM4 ? ? 'expression tag'        -12 28 
2 9K0A HIS B 9  ? UNP E4NIM4 ? ? 'expression tag'        -11 29 
2 9K0A HIS B 10 ? UNP E4NIM4 ? ? 'expression tag'        -10 30 
2 9K0A SER B 11 ? UNP E4NIM4 ? ? 'expression tag'        -9  31 
2 9K0A SER B 12 ? UNP E4NIM4 ? ? 'expression tag'        -8  32 
2 9K0A GLY B 13 ? UNP E4NIM4 ? ? 'expression tag'        -7  33 
2 9K0A LEU B 14 ? UNP E4NIM4 ? ? 'expression tag'        -6  34 
2 9K0A VAL B 15 ? UNP E4NIM4 ? ? 'expression tag'        -5  35 
2 9K0A PRO B 16 ? UNP E4NIM4 ? ? 'expression tag'        -4  36 
2 9K0A ARG B 17 ? UNP E4NIM4 ? ? 'expression tag'        -3  37 
2 9K0A GLY B 18 ? UNP E4NIM4 ? ? 'expression tag'        -2  38 
2 9K0A SER B 19 ? UNP E4NIM4 ? ? 'expression tag'        -1  39 
2 9K0A HIS B 20 ? UNP E4NIM4 ? ? 'expression tag'        0   40 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6990  ? 
1 MORE         -46   ? 
1 'SSA (A^2)'  20600 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 24  ? VAL A 35  ? LEU A 4   VAL A 15  1 ? 12 
HELX_P HELX_P2  AA2 PRO A 39  ? THR A 47  ? PRO A 19  THR A 27  1 ? 9  
HELX_P HELX_P3  AA3 TYR A 60  ? ASP A 87  ? TYR A 40  ASP A 67  1 ? 28 
HELX_P HELX_P4  AA4 SER A 91  ? ASP A 103 ? SER A 71  ASP A 83  1 ? 13 
HELX_P HELX_P5  AA5 ASP A 103 ? TYR A 112 ? ASP A 83  TYR A 92  1 ? 10 
HELX_P HELX_P6  AA6 PHE A 115 ? GLY A 126 ? PHE A 95  GLY A 106 1 ? 12 
HELX_P HELX_P7  AA7 SER A 131 ? PHE A 157 ? SER A 111 PHE A 137 1 ? 27 
HELX_P HELX_P8  AA8 ASN A 222 ? ALA A 232 ? ASN A 202 ALA A 212 1 ? 11 
HELX_P HELX_P9  AA9 CYS A 268 ? ALA A 270 ? CYS A 248 ALA A 250 5 ? 3  
HELX_P HELX_P10 AB1 ASP A 306 ? ASP A 310 ? ASP A 286 ASP A 290 5 ? 5  
HELX_P HELX_P11 AB2 ARG A 311 ? SER A 325 ? ARG A 291 SER A 305 1 ? 15 
HELX_P HELX_P12 AB3 LEU B 24  ? VAL B 35  ? LEU B 4   VAL B 15  1 ? 12 
HELX_P HELX_P13 AB4 PRO B 39  ? THR B 47  ? PRO B 19  THR B 27  1 ? 9  
HELX_P HELX_P14 AB5 TYR B 60  ? THR B 86  ? TYR B 40  THR B 66  1 ? 27 
HELX_P HELX_P15 AB6 SER B 91  ? ASN B 113 ? SER B 71  ASN B 93  1 ? 23 
HELX_P HELX_P16 AB7 PHE B 115 ? GLY B 126 ? PHE B 95  GLY B 106 1 ? 12 
HELX_P HELX_P17 AB8 SER B 131 ? PHE B 157 ? SER B 111 PHE B 137 1 ? 27 
HELX_P HELX_P18 AB9 ASN B 222 ? LEU B 233 ? ASN B 202 LEU B 213 1 ? 12 
HELX_P HELX_P19 AC1 ARG B 266 ? ALA B 270 ? ARG B 246 ALA B 250 5 ? 5  
HELX_P HELX_P20 AC2 ASP B 306 ? ARG B 311 ? ASP B 286 ARG B 291 5 ? 6  
HELX_P HELX_P21 AC3 LEU B 312 ? SER B 325 ? LEU B 292 SER B 305 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 207 A . ? GLN 187 A PRO 208 A ? PRO 188 A 1 5.84  
2 LEU 233 A . ? LEU 213 A PRO 234 A ? PRO 214 A 1 -1.28 
3 GLN 207 B . ? GLN 187 B PRO 208 B ? PRO 188 B 1 3.41  
4 LEU 233 B . ? LEU 213 B PRO 234 B ? PRO 214 B 1 -2.53 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 9 ? 
AA2 ? 6 ? 
AA3 ? 9 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA1 7 8 ? anti-parallel 
AA1 8 9 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
AA3 8 9 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 235 ? LEU A 238 ? PHE A 215 LEU A 218 
AA1 2 TRP A 331 ? ARG A 336 ? TRP A 311 ARG A 316 
AA1 3 ILE A 200 ? GLN A 207 ? ILE A 180 GLN A 187 
AA1 4 VAL A 211 ? ILE A 217 ? VAL A 191 ILE A 197 
AA1 5 SER A 297 ? VAL A 304 ? SER A 277 VAL A 284 
AA1 6 ARG A 274 ? SER A 278 ? ARG A 254 SER A 258 
AA1 7 LYS A 284 ? GLN A 288 ? LYS A 264 GLN A 268 
AA1 8 SER A 248 ? TRP A 252 ? SER A 228 TRP A 232 
AA1 9 ASP A 240 ? HIS A 241 ? ASP A 220 HIS A 221 
AA2 1 PHE A 235 ? LEU A 238 ? PHE A 215 LEU A 218 
AA2 2 TRP A 331 ? ARG A 336 ? TRP A 311 ARG A 316 
AA2 3 ILE A 200 ? GLN A 207 ? ILE A 180 GLN A 187 
AA2 4 VAL A 211 ? ILE A 217 ? VAL A 191 ILE A 197 
AA2 5 SER A 297 ? VAL A 304 ? SER A 277 VAL A 284 
AA2 6 ARG A 264 ? ARG A 266 ? ARG A 244 ARG A 246 
AA3 1 ARG B 199 ? GLN B 207 ? ARG B 179 GLN B 187 
AA3 2 VAL B 211 ? TYR B 218 ? VAL B 191 TYR B 198 
AA3 3 VAL B 300 ? VAL B 304 ? VAL B 280 VAL B 284 
AA3 4 ARG B 274 ? SER B 278 ? ARG B 254 SER B 258 
AA3 5 LYS B 284 ? GLN B 288 ? LYS B 264 GLN B 268 
AA3 6 SER B 248 ? TRP B 252 ? SER B 228 TRP B 232 
AA3 7 PHE B 235 ? HIS B 241 ? PHE B 215 HIS B 221 
AA3 8 VAL B 330 ? ARG B 336 ? VAL B 310 ARG B 316 
AA3 9 ARG B 199 ? GLN B 207 ? ARG B 179 GLN B 187 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 237 ? N VAL A 217 O LEU A 332 ? O LEU A 312 
AA1 2 3 O TRP A 331 ? O TRP A 311 N GLN A 207 ? N GLN A 187 
AA1 3 4 N ILE A 200 ? N ILE A 180 O ILE A 217 ? O ILE A 197 
AA1 4 5 N GLU A 216 ? N GLU A 196 O LYS A 303 ? O LYS A 283 
AA1 5 6 O GLY A 302 ? O GLY A 282 N LEU A 275 ? N LEU A 255 
AA1 6 7 N ARG A 276 ? N ARG A 256 O ILE A 286 ? O ILE A 266 
AA1 7 8 O VAL A 287 ? O VAL A 267 N MET A 249 ? N MET A 229 
AA1 8 9 O TYR A 250 ? O TYR A 230 N ASP A 240 ? N ASP A 220 
AA2 1 2 N VAL A 237 ? N VAL A 217 O LEU A 332 ? O LEU A 312 
AA2 2 3 O TRP A 331 ? O TRP A 311 N GLN A 207 ? N GLN A 187 
AA2 3 4 N ILE A 200 ? N ILE A 180 O ILE A 217 ? O ILE A 197 
AA2 4 5 N GLU A 216 ? N GLU A 196 O LYS A 303 ? O LYS A 283 
AA2 5 6 O SER A 298 ? O SER A 278 N GLU A 265 ? N GLU A 245 
AA3 1 2 N VAL B 202 ? N VAL B 182 O ALA B 215 ? O ALA B 195 
AA3 2 3 N GLU B 216 ? N GLU B 196 O LYS B 303 ? O LYS B 283 
AA3 3 4 O GLY B 302 ? O GLY B 282 N LEU B 275 ? N LEU B 255 
AA3 4 5 N ARG B 276 ? N ARG B 256 O ILE B 286 ? O ILE B 266 
AA3 5 6 O VAL B 287 ? O VAL B 267 N MET B 249 ? N MET B 229 
AA3 6 7 O TYR B 250 ? O TYR B 230 N ASP B 240 ? N ASP B 220 
AA3 7 8 N GLN B 239 ? N GLN B 219 O VAL B 330 ? O VAL B 310 
AA3 8 9 O GLU B 335 ? O GLU B 315 N ARG B 203 ? N ARG B 183 
# 
_pdbx_entry_details.entry_id                   9K0A 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 33  ? ? 37.51   82.59  
2 1 SER A 305 ? ? -128.91 -74.89 
3 1 LYS A 307 ? ? 59.36   14.58  
4 1 ASP B 32  ? ? 58.28   14.48  
5 1 PHE B 95  ? ? -119.61 71.00  
6 1 ASN B 202 ? ? -110.42 77.46  
7 1 GLU B 227 ? ? -104.95 74.89  
8 1 THR B 272 ? ? -171.41 149.25 
9 1 SER B 305 ? ? -135.80 -55.99 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -19 ? A MET 1   
2   1 Y 1 A GLY -18 ? A GLY 2   
3   1 Y 1 A SER -17 ? A SER 3   
4   1 Y 1 A SER -16 ? A SER 4   
5   1 Y 1 A HIS -15 ? A HIS 5   
6   1 Y 1 A HIS -14 ? A HIS 6   
7   1 Y 1 A HIS -13 ? A HIS 7   
8   1 Y 1 A HIS -12 ? A HIS 8   
9   1 Y 1 A HIS -11 ? A HIS 9   
10  1 Y 1 A HIS -10 ? A HIS 10  
11  1 Y 1 A SER -9  ? A SER 11  
12  1 Y 1 A SER -8  ? A SER 12  
13  1 Y 1 A GLY -7  ? A GLY 13  
14  1 Y 1 A LEU -6  ? A LEU 14  
15  1 Y 1 A VAL -5  ? A VAL 15  
16  1 Y 1 A PRO -4  ? A PRO 16  
17  1 Y 1 A ARG -3  ? A ARG 17  
18  1 Y 1 A GLY -2  ? A GLY 18  
19  1 Y 1 A SER -1  ? A SER 19  
20  1 Y 1 A HIS 0   ? A HIS 20  
21  1 Y 1 A MET 1   ? A MET 21  
22  1 Y 1 A SER 2   ? A SER 22  
23  1 Y 1 A ALA 150 ? A ALA 170 
24  1 Y 1 A GLU 151 ? A GLU 171 
25  1 Y 1 A GLU 152 ? A GLU 172 
26  1 Y 1 A VAL 153 ? A VAL 173 
27  1 Y 1 A ALA 154 ? A ALA 174 
28  1 Y 1 A ALA 155 ? A ALA 175 
29  1 Y 1 A GLN 156 ? A GLN 176 
30  1 Y 1 A ALA 157 ? A ALA 177 
31  1 Y 1 A ALA 158 ? A ALA 178 
32  1 Y 1 A GLU 159 ? A GLU 179 
33  1 Y 1 A ALA 160 ? A ALA 180 
34  1 Y 1 A ALA 161 ? A ALA 181 
35  1 Y 1 A ALA 162 ? A ALA 182 
36  1 Y 1 A ALA 163 ? A ALA 183 
37  1 Y 1 A SER 164 ? A SER 184 
38  1 Y 1 A PRO 165 ? A PRO 185 
39  1 Y 1 A SER 166 ? A SER 186 
40  1 Y 1 A VAL 167 ? A VAL 187 
41  1 Y 1 A ASP 168 ? A ASP 188 
42  1 Y 1 A SER 169 ? A SER 189 
43  1 Y 1 A VAL 170 ? A VAL 190 
44  1 Y 1 A ASP 171 ? A ASP 191 
45  1 Y 1 A SER 172 ? A SER 192 
46  1 Y 1 A LEU 173 ? A LEU 193 
47  1 Y 1 A GLY 174 ? A GLY 194 
48  1 Y 1 A ASP 175 ? A ASP 195 
49  1 Y 1 A PRO 176 ? A PRO 196 
50  1 Y 1 A SER 177 ? A SER 197 
51  1 Y 1 A GLN 178 ? A GLN 198 
52  1 Y 1 B MET -19 ? B MET 1   
53  1 Y 1 B GLY -18 ? B GLY 2   
54  1 Y 1 B SER -17 ? B SER 3   
55  1 Y 1 B SER -16 ? B SER 4   
56  1 Y 1 B HIS -15 ? B HIS 5   
57  1 Y 1 B HIS -14 ? B HIS 6   
58  1 Y 1 B HIS -13 ? B HIS 7   
59  1 Y 1 B HIS -12 ? B HIS 8   
60  1 Y 1 B HIS -11 ? B HIS 9   
61  1 Y 1 B HIS -10 ? B HIS 10  
62  1 Y 1 B SER -9  ? B SER 11  
63  1 Y 1 B SER -8  ? B SER 12  
64  1 Y 1 B GLY -7  ? B GLY 13  
65  1 Y 1 B LEU -6  ? B LEU 14  
66  1 Y 1 B VAL -5  ? B VAL 15  
67  1 Y 1 B PRO -4  ? B PRO 16  
68  1 Y 1 B ARG -3  ? B ARG 17  
69  1 Y 1 B GLY -2  ? B GLY 18  
70  1 Y 1 B SER -1  ? B SER 19  
71  1 Y 1 B HIS 0   ? B HIS 20  
72  1 Y 1 B MET 1   ? B MET 21  
73  1 Y 1 B PRO 34  ? B PRO 54  
74  1 Y 1 B ALA 150 ? B ALA 170 
75  1 Y 1 B GLU 151 ? B GLU 171 
76  1 Y 1 B GLU 152 ? B GLU 172 
77  1 Y 1 B VAL 153 ? B VAL 173 
78  1 Y 1 B ALA 154 ? B ALA 174 
79  1 Y 1 B ALA 155 ? B ALA 175 
80  1 Y 1 B GLN 156 ? B GLN 176 
81  1 Y 1 B ALA 157 ? B ALA 177 
82  1 Y 1 B ALA 158 ? B ALA 178 
83  1 Y 1 B GLU 159 ? B GLU 179 
84  1 Y 1 B ALA 160 ? B ALA 180 
85  1 Y 1 B ALA 161 ? B ALA 181 
86  1 Y 1 B ALA 162 ? B ALA 182 
87  1 Y 1 B ALA 163 ? B ALA 183 
88  1 Y 1 B SER 164 ? B SER 184 
89  1 Y 1 B PRO 165 ? B PRO 185 
90  1 Y 1 B SER 166 ? B SER 186 
91  1 Y 1 B VAL 167 ? B VAL 187 
92  1 Y 1 B ASP 168 ? B ASP 188 
93  1 Y 1 B SER 169 ? B SER 189 
94  1 Y 1 B VAL 170 ? B VAL 190 
95  1 Y 1 B ASP 171 ? B ASP 191 
96  1 Y 1 B SER 172 ? B SER 192 
97  1 Y 1 B LEU 173 ? B LEU 193 
98  1 Y 1 B GLY 174 ? B GLY 194 
99  1 Y 1 B ASP 175 ? B ASP 195 
100 1 Y 1 B PRO 176 ? B PRO 196 
101 1 Y 1 B SER 177 ? B SER 197 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1L46 C01  C Y N 1   
A1L46 C02  C Y N 2   
A1L46 C03  C Y N 3   
A1L46 C04  C Y N 4   
A1L46 C05  C Y N 5   
A1L46 C06  C Y N 6   
A1L46 C07  C Y N 7   
A1L46 C08  C Y N 8   
A1L46 C09  C N S 9   
A1L46 C10  C N S 10  
A1L46 C11  C N N 11  
A1L46 C12  C N N 12  
A1L46 C13  C N N 13  
A1L46 C14  C N N 14  
A1L46 C15  C N N 15  
A1L46 C16  C N N 16  
A1L46 N01  N Y N 17  
A1L46 N02  N N N 18  
A1L46 O01  O N N 19  
A1L46 O02  O N N 20  
A1L46 O03  O N N 21  
A1L46 O04  O N N 22  
A1L46 O05  O N N 23  
A1L46 O06  O N N 24  
A1L46 H01  H N N 25  
A1L46 H02  H N N 26  
A1L46 H03  H N N 27  
A1L46 H04  H N N 28  
A1L46 H07  H N N 29  
A1L46 H09  H N N 30  
A1L46 H08  H N N 31  
A1L46 H12  H N N 32  
A1L46 H13  H N N 33  
A1L46 H15  H N N 34  
A1L46 H14  H N N 35  
A1L46 H05  H N N 36  
A1L46 H06  H N N 37  
A1L46 H2   H N N 38  
A1L46 H3   H N N 39  
A1L46 H4   H N N 40  
ALA   N    N N N 41  
ALA   CA   C N S 42  
ALA   C    C N N 43  
ALA   O    O N N 44  
ALA   CB   C N N 45  
ALA   OXT  O N N 46  
ALA   H    H N N 47  
ALA   H2   H N N 48  
ALA   HA   H N N 49  
ALA   HB1  H N N 50  
ALA   HB2  H N N 51  
ALA   HB3  H N N 52  
ALA   HXT  H N N 53  
ARG   N    N N N 54  
ARG   CA   C N S 55  
ARG   C    C N N 56  
ARG   O    O N N 57  
ARG   CB   C N N 58  
ARG   CG   C N N 59  
ARG   CD   C N N 60  
ARG   NE   N N N 61  
ARG   CZ   C N N 62  
ARG   NH1  N N N 63  
ARG   NH2  N N N 64  
ARG   OXT  O N N 65  
ARG   H    H N N 66  
ARG   H2   H N N 67  
ARG   HA   H N N 68  
ARG   HB2  H N N 69  
ARG   HB3  H N N 70  
ARG   HG2  H N N 71  
ARG   HG3  H N N 72  
ARG   HD2  H N N 73  
ARG   HD3  H N N 74  
ARG   HE   H N N 75  
ARG   HH11 H N N 76  
ARG   HH12 H N N 77  
ARG   HH21 H N N 78  
ARG   HH22 H N N 79  
ARG   HXT  H N N 80  
ASN   N    N N N 81  
ASN   CA   C N S 82  
ASN   C    C N N 83  
ASN   O    O N N 84  
ASN   CB   C N N 85  
ASN   CG   C N N 86  
ASN   OD1  O N N 87  
ASN   ND2  N N N 88  
ASN   OXT  O N N 89  
ASN   H    H N N 90  
ASN   H2   H N N 91  
ASN   HA   H N N 92  
ASN   HB2  H N N 93  
ASN   HB3  H N N 94  
ASN   HD21 H N N 95  
ASN   HD22 H N N 96  
ASN   HXT  H N N 97  
ASP   N    N N N 98  
ASP   CA   C N S 99  
ASP   C    C N N 100 
ASP   O    O N N 101 
ASP   CB   C N N 102 
ASP   CG   C N N 103 
ASP   OD1  O N N 104 
ASP   OD2  O N N 105 
ASP   OXT  O N N 106 
ASP   H    H N N 107 
ASP   H2   H N N 108 
ASP   HA   H N N 109 
ASP   HB2  H N N 110 
ASP   HB3  H N N 111 
ASP   HD2  H N N 112 
ASP   HXT  H N N 113 
CYS   N    N N N 114 
CYS   CA   C N R 115 
CYS   C    C N N 116 
CYS   O    O N N 117 
CYS   CB   C N N 118 
CYS   SG   S N N 119 
CYS   OXT  O N N 120 
CYS   H    H N N 121 
CYS   H2   H N N 122 
CYS   HA   H N N 123 
CYS   HB2  H N N 124 
CYS   HB3  H N N 125 
CYS   HG   H N N 126 
CYS   HXT  H N N 127 
GLN   N    N N N 128 
GLN   CA   C N S 129 
GLN   C    C N N 130 
GLN   O    O N N 131 
GLN   CB   C N N 132 
GLN   CG   C N N 133 
GLN   CD   C N N 134 
GLN   OE1  O N N 135 
GLN   NE2  N N N 136 
GLN   OXT  O N N 137 
GLN   H    H N N 138 
GLN   H2   H N N 139 
GLN   HA   H N N 140 
GLN   HB2  H N N 141 
GLN   HB3  H N N 142 
GLN   HG2  H N N 143 
GLN   HG3  H N N 144 
GLN   HE21 H N N 145 
GLN   HE22 H N N 146 
GLN   HXT  H N N 147 
GLU   N    N N N 148 
GLU   CA   C N S 149 
GLU   C    C N N 150 
GLU   O    O N N 151 
GLU   CB   C N N 152 
GLU   CG   C N N 153 
GLU   CD   C N N 154 
GLU   OE1  O N N 155 
GLU   OE2  O N N 156 
GLU   OXT  O N N 157 
GLU   H    H N N 158 
GLU   H2   H N N 159 
GLU   HA   H N N 160 
GLU   HB2  H N N 161 
GLU   HB3  H N N 162 
GLU   HG2  H N N 163 
GLU   HG3  H N N 164 
GLU   HE2  H N N 165 
GLU   HXT  H N N 166 
GLY   N    N N N 167 
GLY   CA   C N N 168 
GLY   C    C N N 169 
GLY   O    O N N 170 
GLY   OXT  O N N 171 
GLY   H    H N N 172 
GLY   H2   H N N 173 
GLY   HA2  H N N 174 
GLY   HA3  H N N 175 
GLY   HXT  H N N 176 
GOL   C1   C N N 177 
GOL   O1   O N N 178 
GOL   C2   C N N 179 
GOL   O2   O N N 180 
GOL   C3   C N N 181 
GOL   O3   O N N 182 
GOL   H11  H N N 183 
GOL   H12  H N N 184 
GOL   HO1  H N N 185 
GOL   H2   H N N 186 
GOL   HO2  H N N 187 
GOL   H31  H N N 188 
GOL   H32  H N N 189 
GOL   HO3  H N N 190 
HIS   N    N N N 191 
HIS   CA   C N S 192 
HIS   C    C N N 193 
HIS   O    O N N 194 
HIS   CB   C N N 195 
HIS   CG   C Y N 196 
HIS   ND1  N Y N 197 
HIS   CD2  C Y N 198 
HIS   CE1  C Y N 199 
HIS   NE2  N Y N 200 
HIS   OXT  O N N 201 
HIS   H    H N N 202 
HIS   H2   H N N 203 
HIS   HA   H N N 204 
HIS   HB2  H N N 205 
HIS   HB3  H N N 206 
HIS   HD1  H N N 207 
HIS   HD2  H N N 208 
HIS   HE1  H N N 209 
HIS   HE2  H N N 210 
HIS   HXT  H N N 211 
HOH   O    O N N 212 
HOH   H1   H N N 213 
HOH   H2   H N N 214 
ILE   N    N N N 215 
ILE   CA   C N S 216 
ILE   C    C N N 217 
ILE   O    O N N 218 
ILE   CB   C N S 219 
ILE   CG1  C N N 220 
ILE   CG2  C N N 221 
ILE   CD1  C N N 222 
ILE   OXT  O N N 223 
ILE   H    H N N 224 
ILE   H2   H N N 225 
ILE   HA   H N N 226 
ILE   HB   H N N 227 
ILE   HG12 H N N 228 
ILE   HG13 H N N 229 
ILE   HG21 H N N 230 
ILE   HG22 H N N 231 
ILE   HG23 H N N 232 
ILE   HD11 H N N 233 
ILE   HD12 H N N 234 
ILE   HD13 H N N 235 
ILE   HXT  H N N 236 
LEU   N    N N N 237 
LEU   CA   C N S 238 
LEU   C    C N N 239 
LEU   O    O N N 240 
LEU   CB   C N N 241 
LEU   CG   C N N 242 
LEU   CD1  C N N 243 
LEU   CD2  C N N 244 
LEU   OXT  O N N 245 
LEU   H    H N N 246 
LEU   H2   H N N 247 
LEU   HA   H N N 248 
LEU   HB2  H N N 249 
LEU   HB3  H N N 250 
LEU   HG   H N N 251 
LEU   HD11 H N N 252 
LEU   HD12 H N N 253 
LEU   HD13 H N N 254 
LEU   HD21 H N N 255 
LEU   HD22 H N N 256 
LEU   HD23 H N N 257 
LEU   HXT  H N N 258 
LYS   N    N N N 259 
LYS   CA   C N S 260 
LYS   C    C N N 261 
LYS   O    O N N 262 
LYS   CB   C N N 263 
LYS   CG   C N N 264 
LYS   CD   C N N 265 
LYS   CE   C N N 266 
LYS   NZ   N N N 267 
LYS   OXT  O N N 268 
LYS   H    H N N 269 
LYS   H2   H N N 270 
LYS   HA   H N N 271 
LYS   HB2  H N N 272 
LYS   HB3  H N N 273 
LYS   HG2  H N N 274 
LYS   HG3  H N N 275 
LYS   HD2  H N N 276 
LYS   HD3  H N N 277 
LYS   HE2  H N N 278 
LYS   HE3  H N N 279 
LYS   HZ1  H N N 280 
LYS   HZ2  H N N 281 
LYS   HZ3  H N N 282 
LYS   HXT  H N N 283 
MET   N    N N N 284 
MET   CA   C N S 285 
MET   C    C N N 286 
MET   O    O N N 287 
MET   CB   C N N 288 
MET   CG   C N N 289 
MET   SD   S N N 290 
MET   CE   C N N 291 
MET   OXT  O N N 292 
MET   H    H N N 293 
MET   H2   H N N 294 
MET   HA   H N N 295 
MET   HB2  H N N 296 
MET   HB3  H N N 297 
MET   HG2  H N N 298 
MET   HG3  H N N 299 
MET   HE1  H N N 300 
MET   HE2  H N N 301 
MET   HE3  H N N 302 
MET   HXT  H N N 303 
PHE   N    N N N 304 
PHE   CA   C N S 305 
PHE   C    C N N 306 
PHE   O    O N N 307 
PHE   CB   C N N 308 
PHE   CG   C Y N 309 
PHE   CD1  C Y N 310 
PHE   CD2  C Y N 311 
PHE   CE1  C Y N 312 
PHE   CE2  C Y N 313 
PHE   CZ   C Y N 314 
PHE   OXT  O N N 315 
PHE   H    H N N 316 
PHE   H2   H N N 317 
PHE   HA   H N N 318 
PHE   HB2  H N N 319 
PHE   HB3  H N N 320 
PHE   HD1  H N N 321 
PHE   HD2  H N N 322 
PHE   HE1  H N N 323 
PHE   HE2  H N N 324 
PHE   HZ   H N N 325 
PHE   HXT  H N N 326 
PRO   N    N N N 327 
PRO   CA   C N S 328 
PRO   C    C N N 329 
PRO   O    O N N 330 
PRO   CB   C N N 331 
PRO   CG   C N N 332 
PRO   CD   C N N 333 
PRO   OXT  O N N 334 
PRO   H    H N N 335 
PRO   HA   H N N 336 
PRO   HB2  H N N 337 
PRO   HB3  H N N 338 
PRO   HG2  H N N 339 
PRO   HG3  H N N 340 
PRO   HD2  H N N 341 
PRO   HD3  H N N 342 
PRO   HXT  H N N 343 
SER   N    N N N 344 
SER   CA   C N S 345 
SER   C    C N N 346 
SER   O    O N N 347 
SER   CB   C N N 348 
SER   OG   O N N 349 
SER   OXT  O N N 350 
SER   H    H N N 351 
SER   H2   H N N 352 
SER   HA   H N N 353 
SER   HB2  H N N 354 
SER   HB3  H N N 355 
SER   HG   H N N 356 
SER   HXT  H N N 357 
THR   N    N N N 358 
THR   CA   C N S 359 
THR   C    C N N 360 
THR   O    O N N 361 
THR   CB   C N R 362 
THR   OG1  O N N 363 
THR   CG2  C N N 364 
THR   OXT  O N N 365 
THR   H    H N N 366 
THR   H2   H N N 367 
THR   HA   H N N 368 
THR   HB   H N N 369 
THR   HG1  H N N 370 
THR   HG21 H N N 371 
THR   HG22 H N N 372 
THR   HG23 H N N 373 
THR   HXT  H N N 374 
TRP   N    N N N 375 
TRP   CA   C N S 376 
TRP   C    C N N 377 
TRP   O    O N N 378 
TRP   CB   C N N 379 
TRP   CG   C Y N 380 
TRP   CD1  C Y N 381 
TRP   CD2  C Y N 382 
TRP   NE1  N Y N 383 
TRP   CE2  C Y N 384 
TRP   CE3  C Y N 385 
TRP   CZ2  C Y N 386 
TRP   CZ3  C Y N 387 
TRP   CH2  C Y N 388 
TRP   OXT  O N N 389 
TRP   H    H N N 390 
TRP   H2   H N N 391 
TRP   HA   H N N 392 
TRP   HB2  H N N 393 
TRP   HB3  H N N 394 
TRP   HD1  H N N 395 
TRP   HE1  H N N 396 
TRP   HE3  H N N 397 
TRP   HZ2  H N N 398 
TRP   HZ3  H N N 399 
TRP   HH2  H N N 400 
TRP   HXT  H N N 401 
TYR   N    N N N 402 
TYR   CA   C N S 403 
TYR   C    C N N 404 
TYR   O    O N N 405 
TYR   CB   C N N 406 
TYR   CG   C Y N 407 
TYR   CD1  C Y N 408 
TYR   CD2  C Y N 409 
TYR   CE1  C Y N 410 
TYR   CE2  C Y N 411 
TYR   CZ   C Y N 412 
TYR   OH   O N N 413 
TYR   OXT  O N N 414 
TYR   H    H N N 415 
TYR   H2   H N N 416 
TYR   HA   H N N 417 
TYR   HB2  H N N 418 
TYR   HB3  H N N 419 
TYR   HD1  H N N 420 
TYR   HD2  H N N 421 
TYR   HE1  H N N 422 
TYR   HE2  H N N 423 
TYR   HH   H N N 424 
TYR   HXT  H N N 425 
VAL   N    N N N 426 
VAL   CA   C N S 427 
VAL   C    C N N 428 
VAL   O    O N N 429 
VAL   CB   C N N 430 
VAL   CG1  C N N 431 
VAL   CG2  C N N 432 
VAL   OXT  O N N 433 
VAL   H    H N N 434 
VAL   H2   H N N 435 
VAL   HA   H N N 436 
VAL   HB   H N N 437 
VAL   HG11 H N N 438 
VAL   HG12 H N N 439 
VAL   HG13 H N N 440 
VAL   HG21 H N N 441 
VAL   HG22 H N N 442 
VAL   HG23 H N N 443 
VAL   HXT  H N N 444 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1L46 C01 C02  doub Y N 1   
A1L46 C01 C06  sing Y N 2   
A1L46 C02 C03  sing Y N 3   
A1L46 C03 C04  doub Y N 4   
A1L46 C04 C05  sing Y N 5   
A1L46 C04 N01  sing Y N 6   
A1L46 C05 C06  doub Y N 7   
A1L46 C05 C08  sing Y N 8   
A1L46 N01 C07  sing Y N 9   
A1L46 C07 C08  doub Y N 10  
A1L46 C07 C09  sing N N 11  
A1L46 C08 C11  sing N N 12  
A1L46 C09 N02  sing N N 13  
A1L46 C09 C13  sing N N 14  
A1L46 C09 C14  sing N N 15  
A1L46 N02 C10  sing N N 16  
A1L46 C10 C11  sing N N 17  
A1L46 C10 C12  sing N N 18  
A1L46 C12 O01  doub N N 19  
A1L46 C12 O02  sing N N 20  
A1L46 C13 O03  doub N N 21  
A1L46 C13 O04  sing N N 22  
A1L46 C14 C15  sing N N 23  
A1L46 C15 C16  sing N N 24  
A1L46 C16 O05  doub N N 25  
A1L46 C16 O06  sing N N 26  
A1L46 C01 H01  sing N N 27  
A1L46 C02 H02  sing N N 28  
A1L46 C03 H03  sing N N 29  
A1L46 C06 H04  sing N N 30  
A1L46 C10 H07  sing N N 31  
A1L46 C11 H09  sing N N 32  
A1L46 C11 H08  sing N N 33  
A1L46 C14 H12  sing N N 34  
A1L46 C14 H13  sing N N 35  
A1L46 C15 H15  sing N N 36  
A1L46 C15 H14  sing N N 37  
A1L46 N01 H05  sing N N 38  
A1L46 N02 H06  sing N N 39  
A1L46 O02 H2   sing N N 40  
A1L46 O04 H3   sing N N 41  
A1L46 O06 H4   sing N N 42  
ALA   N   CA   sing N N 43  
ALA   N   H    sing N N 44  
ALA   N   H2   sing N N 45  
ALA   CA  C    sing N N 46  
ALA   CA  CB   sing N N 47  
ALA   CA  HA   sing N N 48  
ALA   C   O    doub N N 49  
ALA   C   OXT  sing N N 50  
ALA   CB  HB1  sing N N 51  
ALA   CB  HB2  sing N N 52  
ALA   CB  HB3  sing N N 53  
ALA   OXT HXT  sing N N 54  
ARG   N   CA   sing N N 55  
ARG   N   H    sing N N 56  
ARG   N   H2   sing N N 57  
ARG   CA  C    sing N N 58  
ARG   CA  CB   sing N N 59  
ARG   CA  HA   sing N N 60  
ARG   C   O    doub N N 61  
ARG   C   OXT  sing N N 62  
ARG   CB  CG   sing N N 63  
ARG   CB  HB2  sing N N 64  
ARG   CB  HB3  sing N N 65  
ARG   CG  CD   sing N N 66  
ARG   CG  HG2  sing N N 67  
ARG   CG  HG3  sing N N 68  
ARG   CD  NE   sing N N 69  
ARG   CD  HD2  sing N N 70  
ARG   CD  HD3  sing N N 71  
ARG   NE  CZ   sing N N 72  
ARG   NE  HE   sing N N 73  
ARG   CZ  NH1  sing N N 74  
ARG   CZ  NH2  doub N N 75  
ARG   NH1 HH11 sing N N 76  
ARG   NH1 HH12 sing N N 77  
ARG   NH2 HH21 sing N N 78  
ARG   NH2 HH22 sing N N 79  
ARG   OXT HXT  sing N N 80  
ASN   N   CA   sing N N 81  
ASN   N   H    sing N N 82  
ASN   N   H2   sing N N 83  
ASN   CA  C    sing N N 84  
ASN   CA  CB   sing N N 85  
ASN   CA  HA   sing N N 86  
ASN   C   O    doub N N 87  
ASN   C   OXT  sing N N 88  
ASN   CB  CG   sing N N 89  
ASN   CB  HB2  sing N N 90  
ASN   CB  HB3  sing N N 91  
ASN   CG  OD1  doub N N 92  
ASN   CG  ND2  sing N N 93  
ASN   ND2 HD21 sing N N 94  
ASN   ND2 HD22 sing N N 95  
ASN   OXT HXT  sing N N 96  
ASP   N   CA   sing N N 97  
ASP   N   H    sing N N 98  
ASP   N   H2   sing N N 99  
ASP   CA  C    sing N N 100 
ASP   CA  CB   sing N N 101 
ASP   CA  HA   sing N N 102 
ASP   C   O    doub N N 103 
ASP   C   OXT  sing N N 104 
ASP   CB  CG   sing N N 105 
ASP   CB  HB2  sing N N 106 
ASP   CB  HB3  sing N N 107 
ASP   CG  OD1  doub N N 108 
ASP   CG  OD2  sing N N 109 
ASP   OD2 HD2  sing N N 110 
ASP   OXT HXT  sing N N 111 
CYS   N   CA   sing N N 112 
CYS   N   H    sing N N 113 
CYS   N   H2   sing N N 114 
CYS   CA  C    sing N N 115 
CYS   CA  CB   sing N N 116 
CYS   CA  HA   sing N N 117 
CYS   C   O    doub N N 118 
CYS   C   OXT  sing N N 119 
CYS   CB  SG   sing N N 120 
CYS   CB  HB2  sing N N 121 
CYS   CB  HB3  sing N N 122 
CYS   SG  HG   sing N N 123 
CYS   OXT HXT  sing N N 124 
GLN   N   CA   sing N N 125 
GLN   N   H    sing N N 126 
GLN   N   H2   sing N N 127 
GLN   CA  C    sing N N 128 
GLN   CA  CB   sing N N 129 
GLN   CA  HA   sing N N 130 
GLN   C   O    doub N N 131 
GLN   C   OXT  sing N N 132 
GLN   CB  CG   sing N N 133 
GLN   CB  HB2  sing N N 134 
GLN   CB  HB3  sing N N 135 
GLN   CG  CD   sing N N 136 
GLN   CG  HG2  sing N N 137 
GLN   CG  HG3  sing N N 138 
GLN   CD  OE1  doub N N 139 
GLN   CD  NE2  sing N N 140 
GLN   NE2 HE21 sing N N 141 
GLN   NE2 HE22 sing N N 142 
GLN   OXT HXT  sing N N 143 
GLU   N   CA   sing N N 144 
GLU   N   H    sing N N 145 
GLU   N   H2   sing N N 146 
GLU   CA  C    sing N N 147 
GLU   CA  CB   sing N N 148 
GLU   CA  HA   sing N N 149 
GLU   C   O    doub N N 150 
GLU   C   OXT  sing N N 151 
GLU   CB  CG   sing N N 152 
GLU   CB  HB2  sing N N 153 
GLU   CB  HB3  sing N N 154 
GLU   CG  CD   sing N N 155 
GLU   CG  HG2  sing N N 156 
GLU   CG  HG3  sing N N 157 
GLU   CD  OE1  doub N N 158 
GLU   CD  OE2  sing N N 159 
GLU   OE2 HE2  sing N N 160 
GLU   OXT HXT  sing N N 161 
GLY   N   CA   sing N N 162 
GLY   N   H    sing N N 163 
GLY   N   H2   sing N N 164 
GLY   CA  C    sing N N 165 
GLY   CA  HA2  sing N N 166 
GLY   CA  HA3  sing N N 167 
GLY   C   O    doub N N 168 
GLY   C   OXT  sing N N 169 
GLY   OXT HXT  sing N N 170 
GOL   C1  O1   sing N N 171 
GOL   C1  C2   sing N N 172 
GOL   C1  H11  sing N N 173 
GOL   C1  H12  sing N N 174 
GOL   O1  HO1  sing N N 175 
GOL   C2  O2   sing N N 176 
GOL   C2  C3   sing N N 177 
GOL   C2  H2   sing N N 178 
GOL   O2  HO2  sing N N 179 
GOL   C3  O3   sing N N 180 
GOL   C3  H31  sing N N 181 
GOL   C3  H32  sing N N 182 
GOL   O3  HO3  sing N N 183 
HIS   N   CA   sing N N 184 
HIS   N   H    sing N N 185 
HIS   N   H2   sing N N 186 
HIS   CA  C    sing N N 187 
HIS   CA  CB   sing N N 188 
HIS   CA  HA   sing N N 189 
HIS   C   O    doub N N 190 
HIS   C   OXT  sing N N 191 
HIS   CB  CG   sing N N 192 
HIS   CB  HB2  sing N N 193 
HIS   CB  HB3  sing N N 194 
HIS   CG  ND1  sing Y N 195 
HIS   CG  CD2  doub Y N 196 
HIS   ND1 CE1  doub Y N 197 
HIS   ND1 HD1  sing N N 198 
HIS   CD2 NE2  sing Y N 199 
HIS   CD2 HD2  sing N N 200 
HIS   CE1 NE2  sing Y N 201 
HIS   CE1 HE1  sing N N 202 
HIS   NE2 HE2  sing N N 203 
HIS   OXT HXT  sing N N 204 
HOH   O   H1   sing N N 205 
HOH   O   H2   sing N N 206 
ILE   N   CA   sing N N 207 
ILE   N   H    sing N N 208 
ILE   N   H2   sing N N 209 
ILE   CA  C    sing N N 210 
ILE   CA  CB   sing N N 211 
ILE   CA  HA   sing N N 212 
ILE   C   O    doub N N 213 
ILE   C   OXT  sing N N 214 
ILE   CB  CG1  sing N N 215 
ILE   CB  CG2  sing N N 216 
ILE   CB  HB   sing N N 217 
ILE   CG1 CD1  sing N N 218 
ILE   CG1 HG12 sing N N 219 
ILE   CG1 HG13 sing N N 220 
ILE   CG2 HG21 sing N N 221 
ILE   CG2 HG22 sing N N 222 
ILE   CG2 HG23 sing N N 223 
ILE   CD1 HD11 sing N N 224 
ILE   CD1 HD12 sing N N 225 
ILE   CD1 HD13 sing N N 226 
ILE   OXT HXT  sing N N 227 
LEU   N   CA   sing N N 228 
LEU   N   H    sing N N 229 
LEU   N   H2   sing N N 230 
LEU   CA  C    sing N N 231 
LEU   CA  CB   sing N N 232 
LEU   CA  HA   sing N N 233 
LEU   C   O    doub N N 234 
LEU   C   OXT  sing N N 235 
LEU   CB  CG   sing N N 236 
LEU   CB  HB2  sing N N 237 
LEU   CB  HB3  sing N N 238 
LEU   CG  CD1  sing N N 239 
LEU   CG  CD2  sing N N 240 
LEU   CG  HG   sing N N 241 
LEU   CD1 HD11 sing N N 242 
LEU   CD1 HD12 sing N N 243 
LEU   CD1 HD13 sing N N 244 
LEU   CD2 HD21 sing N N 245 
LEU   CD2 HD22 sing N N 246 
LEU   CD2 HD23 sing N N 247 
LEU   OXT HXT  sing N N 248 
LYS   N   CA   sing N N 249 
LYS   N   H    sing N N 250 
LYS   N   H2   sing N N 251 
LYS   CA  C    sing N N 252 
LYS   CA  CB   sing N N 253 
LYS   CA  HA   sing N N 254 
LYS   C   O    doub N N 255 
LYS   C   OXT  sing N N 256 
LYS   CB  CG   sing N N 257 
LYS   CB  HB2  sing N N 258 
LYS   CB  HB3  sing N N 259 
LYS   CG  CD   sing N N 260 
LYS   CG  HG2  sing N N 261 
LYS   CG  HG3  sing N N 262 
LYS   CD  CE   sing N N 263 
LYS   CD  HD2  sing N N 264 
LYS   CD  HD3  sing N N 265 
LYS   CE  NZ   sing N N 266 
LYS   CE  HE2  sing N N 267 
LYS   CE  HE3  sing N N 268 
LYS   NZ  HZ1  sing N N 269 
LYS   NZ  HZ2  sing N N 270 
LYS   NZ  HZ3  sing N N 271 
LYS   OXT HXT  sing N N 272 
MET   N   CA   sing N N 273 
MET   N   H    sing N N 274 
MET   N   H2   sing N N 275 
MET   CA  C    sing N N 276 
MET   CA  CB   sing N N 277 
MET   CA  HA   sing N N 278 
MET   C   O    doub N N 279 
MET   C   OXT  sing N N 280 
MET   CB  CG   sing N N 281 
MET   CB  HB2  sing N N 282 
MET   CB  HB3  sing N N 283 
MET   CG  SD   sing N N 284 
MET   CG  HG2  sing N N 285 
MET   CG  HG3  sing N N 286 
MET   SD  CE   sing N N 287 
MET   CE  HE1  sing N N 288 
MET   CE  HE2  sing N N 289 
MET   CE  HE3  sing N N 290 
MET   OXT HXT  sing N N 291 
PHE   N   CA   sing N N 292 
PHE   N   H    sing N N 293 
PHE   N   H2   sing N N 294 
PHE   CA  C    sing N N 295 
PHE   CA  CB   sing N N 296 
PHE   CA  HA   sing N N 297 
PHE   C   O    doub N N 298 
PHE   C   OXT  sing N N 299 
PHE   CB  CG   sing N N 300 
PHE   CB  HB2  sing N N 301 
PHE   CB  HB3  sing N N 302 
PHE   CG  CD1  doub Y N 303 
PHE   CG  CD2  sing Y N 304 
PHE   CD1 CE1  sing Y N 305 
PHE   CD1 HD1  sing N N 306 
PHE   CD2 CE2  doub Y N 307 
PHE   CD2 HD2  sing N N 308 
PHE   CE1 CZ   doub Y N 309 
PHE   CE1 HE1  sing N N 310 
PHE   CE2 CZ   sing Y N 311 
PHE   CE2 HE2  sing N N 312 
PHE   CZ  HZ   sing N N 313 
PHE   OXT HXT  sing N N 314 
PRO   N   CA   sing N N 315 
PRO   N   CD   sing N N 316 
PRO   N   H    sing N N 317 
PRO   CA  C    sing N N 318 
PRO   CA  CB   sing N N 319 
PRO   CA  HA   sing N N 320 
PRO   C   O    doub N N 321 
PRO   C   OXT  sing N N 322 
PRO   CB  CG   sing N N 323 
PRO   CB  HB2  sing N N 324 
PRO   CB  HB3  sing N N 325 
PRO   CG  CD   sing N N 326 
PRO   CG  HG2  sing N N 327 
PRO   CG  HG3  sing N N 328 
PRO   CD  HD2  sing N N 329 
PRO   CD  HD3  sing N N 330 
PRO   OXT HXT  sing N N 331 
SER   N   CA   sing N N 332 
SER   N   H    sing N N 333 
SER   N   H2   sing N N 334 
SER   CA  C    sing N N 335 
SER   CA  CB   sing N N 336 
SER   CA  HA   sing N N 337 
SER   C   O    doub N N 338 
SER   C   OXT  sing N N 339 
SER   CB  OG   sing N N 340 
SER   CB  HB2  sing N N 341 
SER   CB  HB3  sing N N 342 
SER   OG  HG   sing N N 343 
SER   OXT HXT  sing N N 344 
THR   N   CA   sing N N 345 
THR   N   H    sing N N 346 
THR   N   H2   sing N N 347 
THR   CA  C    sing N N 348 
THR   CA  CB   sing N N 349 
THR   CA  HA   sing N N 350 
THR   C   O    doub N N 351 
THR   C   OXT  sing N N 352 
THR   CB  OG1  sing N N 353 
THR   CB  CG2  sing N N 354 
THR   CB  HB   sing N N 355 
THR   OG1 HG1  sing N N 356 
THR   CG2 HG21 sing N N 357 
THR   CG2 HG22 sing N N 358 
THR   CG2 HG23 sing N N 359 
THR   OXT HXT  sing N N 360 
TRP   N   CA   sing N N 361 
TRP   N   H    sing N N 362 
TRP   N   H2   sing N N 363 
TRP   CA  C    sing N N 364 
TRP   CA  CB   sing N N 365 
TRP   CA  HA   sing N N 366 
TRP   C   O    doub N N 367 
TRP   C   OXT  sing N N 368 
TRP   CB  CG   sing N N 369 
TRP   CB  HB2  sing N N 370 
TRP   CB  HB3  sing N N 371 
TRP   CG  CD1  doub Y N 372 
TRP   CG  CD2  sing Y N 373 
TRP   CD1 NE1  sing Y N 374 
TRP   CD1 HD1  sing N N 375 
TRP   CD2 CE2  doub Y N 376 
TRP   CD2 CE3  sing Y N 377 
TRP   NE1 CE2  sing Y N 378 
TRP   NE1 HE1  sing N N 379 
TRP   CE2 CZ2  sing Y N 380 
TRP   CE3 CZ3  doub Y N 381 
TRP   CE3 HE3  sing N N 382 
TRP   CZ2 CH2  doub Y N 383 
TRP   CZ2 HZ2  sing N N 384 
TRP   CZ3 CH2  sing Y N 385 
TRP   CZ3 HZ3  sing N N 386 
TRP   CH2 HH2  sing N N 387 
TRP   OXT HXT  sing N N 388 
TYR   N   CA   sing N N 389 
TYR   N   H    sing N N 390 
TYR   N   H2   sing N N 391 
TYR   CA  C    sing N N 392 
TYR   CA  CB   sing N N 393 
TYR   CA  HA   sing N N 394 
TYR   C   O    doub N N 395 
TYR   C   OXT  sing N N 396 
TYR   CB  CG   sing N N 397 
TYR   CB  HB2  sing N N 398 
TYR   CB  HB3  sing N N 399 
TYR   CG  CD1  doub Y N 400 
TYR   CG  CD2  sing Y N 401 
TYR   CD1 CE1  sing Y N 402 
TYR   CD1 HD1  sing N N 403 
TYR   CD2 CE2  doub Y N 404 
TYR   CD2 HD2  sing N N 405 
TYR   CE1 CZ   doub Y N 406 
TYR   CE1 HE1  sing N N 407 
TYR   CE2 CZ   sing Y N 408 
TYR   CE2 HE2  sing N N 409 
TYR   CZ  OH   sing N N 410 
TYR   OH  HH   sing N N 411 
TYR   OXT HXT  sing N N 412 
VAL   N   CA   sing N N 413 
VAL   N   H    sing N N 414 
VAL   N   H2   sing N N 415 
VAL   CA  C    sing N N 416 
VAL   CA  CB   sing N N 417 
VAL   CA  HA   sing N N 418 
VAL   C   O    doub N N 419 
VAL   C   OXT  sing N N 420 
VAL   CB  CG1  sing N N 421 
VAL   CB  CG2  sing N N 422 
VAL   CB  HB   sing N N 423 
VAL   CG1 HG11 sing N N 424 
VAL   CG1 HG12 sing N N 425 
VAL   CG1 HG13 sing N N 426 
VAL   CG2 HG21 sing N N 427 
VAL   CG2 HG22 sing N N 428 
VAL   CG2 HG23 sing N N 429 
VAL   OXT HXT  sing N N 430 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9K0A 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.017520 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.006143 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012049 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.016429 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C   ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N   ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O   ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O1- ? ? 5.12366 3.84317 ? ? 3.49406  27.47979 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S   ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ALA   A 1 23  ? -21.12293 16.35562  14.77109  1.000 32.79995 ?  3   ALA   A N   1 
ATOM   2    C CA  . ALA   A 1 23  ? -20.91925 16.48019  16.20965  1.000 35.46719 ?  3   ALA   A CA  1 
ATOM   3    C C   . ALA   A 1 23  ? -19.57650 17.13225  16.51690  1.000 39.84692 ?  3   ALA   A C   1 
ATOM   4    O O   . ALA   A 1 23  ? -19.50354 18.11466  17.25771  1.000 42.62390 ?  3   ALA   A O   1 
ATOM   5    C CB  . ALA   A 1 23  ? -21.00986 15.11735  16.87670  1.000 30.71533 ?  3   ALA   A CB  1 
ATOM   6    N N   . LEU   A 1 24  ? -18.51539 16.57152  15.94058  1.000 31.30038 ?  4   LEU   A N   1 
ATOM   7    C CA  . LEU   A 1 24  ? -17.14927 17.06415  16.11522  1.000 22.13799 ?  4   LEU   A CA  1 
ATOM   8    C C   . LEU   A 1 24  ? -16.54931 17.32062  14.73833  1.000 25.33972 ?  4   LEU   A C   1 
ATOM   9    O O   . LEU   A 1 24  ? -15.64383 16.60190  14.29743  1.000 24.73159 ?  4   LEU   A O   1 
ATOM   10   C CB  . LEU   A 1 24  ? -16.30690 16.06111  16.90491  1.000 23.58344 ?  4   LEU   A CB  1 
ATOM   11   C CG  . LEU   A 1 24  ? -16.95010 15.47088  18.16445  1.000 24.73978 ?  4   LEU   A CG  1 
ATOM   12   C CD1 . LEU   A 1 24  ? -16.02648 14.45146  18.80326  1.000 20.02395 ?  4   LEU   A CD1 1 
ATOM   13   C CD2 . LEU   A 1 24  ? -17.31324 16.55999  19.16141  1.000 26.45588 ?  4   LEU   A CD2 1 
ATOM   14   N N   . PRO   A 1 25  ? -17.03024 18.35020  14.03285  1.000 23.46118 ?  5   PRO   A N   1 
ATOM   15   C CA  . PRO   A 1 25  ? -16.62885 18.52596  12.62551  1.000 23.04523 ?  5   PRO   A CA  1 
ATOM   16   C C   . PRO   A 1 25  ? -15.13765 18.72826  12.42542  1.000 24.15795 ?  5   PRO   A C   1 
ATOM   17   O O   . PRO   A 1 25  ? -14.60835 18.34927  11.37255  1.000 20.89343 ?  5   PRO   A O   1 
ATOM   18   C CB  . PRO   A 1 25  ? -17.42411 19.76577  12.18962  1.000 27.91811 ?  5   PRO   A CB  1 
ATOM   19   C CG  . PRO   A 1 25  ? -17.76084 20.47293  13.47122  1.000 25.74539 ?  5   PRO   A CG  1 
ATOM   20   C CD  . PRO   A 1 25  ? -17.99327 19.37832  14.46035  1.000 22.71361 ?  5   PRO   A CD  1 
ATOM   21   N N   . GLU   A 1 26  ? -14.44175 19.32293  13.39640  1.000 19.83088 ?  6   GLU   A N   1 
ATOM   22   C CA  . GLU   A 1 26  ? -13.00405 19.52272  13.24698  1.000 22.82649 ?  6   GLU   A CA  1 
ATOM   23   C C   . GLU   A 1 26  ? -12.25193 18.20263  13.35899  1.000 22.73784 ?  6   GLU   A C   1 
ATOM   24   O O   . GLU   A 1 26  ? -11.24590 17.99521  12.67069  1.000 21.30955 ?  6   GLU   A O   1 
ATOM   25   C CB  . GLU   A 1 26  ? -12.50080 20.52690  14.28391  1.000 28.21512 ?  6   GLU   A CB  1 
ATOM   26   C CG  . GLU   A 1 26  ? -10.98835 20.71944  14.30228  1.000 22.67190 ?  6   GLU   A CG  1 
ATOM   27   C CD  . GLU   A 1 26  ? -10.54351 21.77674  15.30025  1.000 29.50586 ?  6   GLU   A CD  1 
ATOM   28   O OE1 . GLU   A 1 26  ? -11.01323 21.74189  16.45754  1.000 25.97416 ?  6   GLU   A OE1 1 
ATOM   29   O OE2 . GLU   A 1 26  ? -9.72601  22.64505  14.92677  1.000 25.21078 ?  6   GLU   A OE2 1 
ATOM   30   N N   . LEU   A 1 27  ? -12.72421 17.29547  14.21770  1.000 20.78321 ?  7   LEU   A N   1 
ATOM   31   C CA  . LEU   A 1 27  ? -12.12218 15.96798  14.28186  1.000 24.28360 ?  7   LEU   A CA  1 
ATOM   32   C C   . LEU   A 1 27  ? -12.31719 15.20576  12.97793  1.000 26.14165 ?  7   LEU   A C   1 
ATOM   33   O O   . LEU   A 1 27  ? -11.45728 14.40578  12.59185  1.000 24.15819 ?  7   LEU   A O   1 
ATOM   34   C CB  . LEU   A 1 27  ? -12.70712 15.17800  15.45265  1.000 25.38315 ?  7   LEU   A CB  1 
ATOM   35   C CG  . LEU   A 1 27  ? -12.23776 15.56200  16.85690  1.000 20.01885 ?  7   LEU   A CG  1 
ATOM   36   C CD1 . LEU   A 1 27  ? -12.49576 14.41671  17.81731  1.000 14.85908 ?  7   LEU   A CD1 1 
ATOM   37   C CD2 . LEU   A 1 27  ? -10.76403 15.94077  16.86053  1.000 20.28505 ?  7   LEU   A CD2 1 
ATOM   38   N N   . ARG   A 1 28  ? -13.43670 15.43909  12.28835  1.000 25.70032 ?  8   ARG   A N   1 
ATOM   39   C CA  . ARG   A 1 28  ? -13.65040 14.81422  10.98685  1.000 24.96039 ?  8   ARG   A CA  1 
ATOM   40   C C   . ARG   A 1 28  ? -12.62828 15.30134  9.96725   1.000 22.62247 ?  8   ARG   A C   1 
ATOM   41   O O   . ARG   A 1 28  ? -12.13759 14.51810  9.14567   1.000 22.10106 ?  8   ARG   A O   1 
ATOM   42   C CB  . ARG   A 1 28  ? -15.07304 15.09436  10.50078  1.000 25.42688 ?  8   ARG   A CB  1 
ATOM   43   C CG  . ARG   A 1 28  ? -15.56438 14.16114  9.40200   1.000 38.20640 ?  8   ARG   A CG  1 
ATOM   44   C CD  . ARG   A 1 28  ? -15.12115 12.72598  9.63892   1.000 43.09546 ?  8   ARG   A CD  1 
ATOM   45   N NE  . ARG   A 1 28  ? -15.86140 12.09273  10.72392  1.000 43.09728 ?  8   ARG   A NE  1 
ATOM   46   C CZ  . ARG   A 1 28  ? -15.80776 10.79943  11.01175  1.000 36.78875 ?  8   ARG   A CZ  1 
ATOM   47   N NH1 . ARG   A 1 28  ? -15.06397 9.96409   10.30481  1.000 33.64555 ?  8   ARG   A NH1 1 
ATOM   48   N NH2 . ARG   A 1 28  ? -16.52015 10.33201  12.03286  1.000 35.96506 ?  8   ARG   A NH2 1 
ATOM   49   N N   . GLU   A 1 29  ? -12.29312 16.59298  10.00477  1.000 20.60414 ?  9   GLU   A N   1 
ATOM   50   C CA  . GLU   A 1 29  ? -11.28460 17.11868  9.09029   1.000 21.69140 ?  9   GLU   A CA  1 
ATOM   51   C C   . GLU   A 1 29  ? -9.90355  16.55628  9.40604   1.000 22.37136 ?  9   GLU   A C   1 
ATOM   52   O O   . GLU   A 1 29  ? -9.13411  16.23667  8.49239   1.000 21.70128 ?  9   GLU   A O   1 
ATOM   53   C CB  . GLU   A 1 29  ? -11.26717 18.64614  9.14852   1.000 25.49589 ?  9   GLU   A CB  1 
ATOM   54   C CG  . GLU   A 1 29  ? -12.52798 19.30525  8.61488   1.000 30.82704 ?  9   GLU   A CG  1 
ATOM   55   C CD  . GLU   A 1 29  ? -12.43835 20.81885  8.62825   1.000 57.04896 ?  9   GLU   A CD  1 
ATOM   56   O OE1 . GLU   A 1 29  ? -11.43956 21.35116  9.15800   1.000 51.41618 ?  9   GLU   A OE1 1 
ATOM   57   O OE2 . GLU   A 1 29  ? -13.36691 21.47674  8.11294   1.000 55.85569 ?  9   GLU   A OE2 1 
ATOM   58   N N   . LEU   A 1 30  ? -9.57041  16.42772  10.69262  1.000 19.02864 ?  10  LEU   A N   1 
ATOM   59   C CA  . LEU   A 1 30  ? -8.26714  15.88542  11.06382  1.000 18.88245 ?  10  LEU   A CA  1 
ATOM   60   C C   . LEU   A 1 30  ? -8.16483  14.40475  10.71898  1.000 19.76643 ?  10  LEU   A C   1 
ATOM   61   O O   . LEU   A 1 30  ? -7.09236  13.92638  10.33119  1.000 21.09900 ?  10  LEU   A O   1 
ATOM   62   C CB  . LEU   A 1 30  ? -8.00875  16.11154  12.55293  1.000 18.42977 ?  10  LEU   A CB  1 
ATOM   63   C CG  . LEU   A 1 30  ? -7.89803  17.57031  12.99969  1.000 18.90890 ?  10  LEU   A CG  1 
ATOM   64   C CD1 . LEU   A 1 30  ? -7.62587  17.65403  14.49344  1.000 20.35877 ?  10  LEU   A CD1 1 
ATOM   65   C CD2 . LEU   A 1 30  ? -6.81315  18.29103  12.21305  1.000 20.89039 ?  10  LEU   A CD2 1 
ATOM   66   N N   . ILE   A 1 31  ? -9.26742  13.66350  10.85831  1.000 15.86273 ?  11  ILE   A N   1 
ATOM   67   C CA  . ILE   A 1 31  ? -9.27518  12.25647  10.46450  1.000 20.32653 ?  11  ILE   A CA  1 
ATOM   68   C C   . ILE   A 1 31  ? -8.98550  12.11998  8.97540   1.000 22.09324 ?  11  ILE   A C   1 
ATOM   69   O O   . ILE   A 1 31  ? -8.20665  11.25502  8.55457   1.000 21.42233 ?  11  ILE   A O   1 
ATOM   70   C CB  . ILE   A 1 31  ? -10.61787 11.60213  10.84241  1.000 22.38345 ?  11  ILE   A CB  1 
ATOM   71   C CG1 . ILE   A 1 31  ? -10.65815 11.27814  12.33654  1.000 16.94203 ?  11  ILE   A CG1 1 
ATOM   72   C CG2 . ILE   A 1 31  ? -10.86450 10.34893  10.01060  1.000 21.71453 ?  11  ILE   A CG2 1 
ATOM   73   C CD1 . ILE   A 1 31  ? -12.06128 11.18501  12.89535  1.000 21.31328 ?  11  ILE   A CD1 1 
ATOM   74   N N   . ALA   A 1 32  ? -9.60078  12.97591  8.15514   1.000 21.92758 ?  12  ALA   A N   1 
ATOM   75   C CA  . ALA   A 1 32  ? -9.36613  12.92110  6.71652   1.000 21.87977 ?  12  ALA   A CA  1 
ATOM   76   C C   . ALA   A 1 32  ? -7.93712  13.31017  6.36263   1.000 21.65586 ?  12  ALA   A C   1 
ATOM   77   O O   . ALA   A 1 32  ? -7.37032  12.77643  5.40220   1.000 25.33495 ?  12  ALA   A O   1 
ATOM   78   C CB  . ALA   A 1 32  ? -10.35831 13.82676  5.98690   1.000 21.72919 ?  12  ALA   A CB  1 
ATOM   79   N N   . SER   A 1 33  ? -7.33837  14.22841  7.12177   1.000 19.61734 ?  13  SER   A N   1 
ATOM   80   C CA  . SER   A 1 33  ? -5.97139  14.64651  6.83120   1.000 21.78038 ?  13  SER   A CA  1 
ATOM   81   C C   . SER   A 1 33  ? -4.96748  13.57556  7.24065   1.000 28.74820 ?  13  SER   A C   1 
ATOM   82   O O   . SER   A 1 33  ? -4.05290  13.24217  6.47696   1.000 28.87745 ?  13  SER   A O   1 
ATOM   83   C CB  . SER   A 1 33  ? -5.66671  15.96562  7.53963   1.000 20.66651 ?  13  SER   A CB  1 
ATOM   84   O OG  . SER   A 1 33  ? -6.47536  17.01127  7.03112   1.000 32.07787 ?  13  SER   A OG  1 
ATOM   85   N N   . PHE   A 1 34  ? -5.12715  13.01930  8.44363   1.000 25.23463 ?  14  PHE   A N   1 
ATOM   86   C CA  . PHE   A 1 34  ? -4.14654  12.09656  9.00721   1.000 22.26567 ?  14  PHE   A CA  1 
ATOM   87   C C   . PHE   A 1 34  ? -4.17844  10.71293  8.36838   1.000 24.34279 ?  14  PHE   A C   1 
ATOM   88   O O   . PHE   A 1 34  ? -3.36013  9.86629   8.74546   1.000 22.01320 ?  14  PHE   A O   1 
ATOM   89   C CB  . PHE   A 1 34  ? -4.35700  11.97318  10.51806  1.000 21.45213 ?  14  PHE   A CB  1 
ATOM   90   C CG  . PHE   A 1 34  ? -4.13660  13.25720  11.26773  1.000 20.94436 ?  14  PHE   A CG  1 
ATOM   91   C CD1 . PHE   A 1 34  ? -3.35795  14.26731  10.72494  1.000 23.95828 ?  14  PHE   A CD1 1 
ATOM   92   C CD2 . PHE   A 1 34  ? -4.70992  13.45642  12.51302  1.000 26.12887 ?  14  PHE   A CD2 1 
ATOM   93   C CE1 . PHE   A 1 34  ? -3.15513  15.45237  11.40866  1.000 25.87184 ?  14  PHE   A CE1 1 
ATOM   94   C CE2 . PHE   A 1 34  ? -4.50981  14.64023  13.20376  1.000 22.97721 ?  14  PHE   A CE2 1 
ATOM   95   C CZ  . PHE   A 1 34  ? -3.73109  15.63892  12.65030  1.000 26.11099 ?  14  PHE   A CZ  1 
ATOM   96   N N   . VAL   A 1 35  ? -5.08815  10.45697  7.42456   1.000 24.17997 ?  15  VAL   A N   1 
ATOM   97   C CA  . VAL   A 1 35  ? -5.09199  9.16842   6.73969   1.000 25.63826 ?  15  VAL   A CA  1 
ATOM   98   C C   . VAL   A 1 35  ? -3.84731  9.01720   5.87362   1.000 27.73666 ?  15  VAL   A C   1 
ATOM   99   O O   . VAL   A 1 35  ? -3.40963  7.89448   5.59206   1.000 34.25897 ?  15  VAL   A O   1 
ATOM   100  C CB  . VAL   A 1 35  ? -6.38592  9.00248   5.91858   1.000 25.18028 ?  15  VAL   A CB  1 
ATOM   101  C CG1 . VAL   A 1 35  ? -6.25231  9.65650   4.55077   1.000 21.58324 ?  15  VAL   A CG1 1 
ATOM   102  C CG2 . VAL   A 1 35  ? -6.73905  7.53229   5.77250   1.000 26.05646 ?  15  VAL   A CG2 1 
ATOM   103  N N   . SER   A 1 36  ? -3.24961  10.13260  5.45007   1.000 26.52479 ?  16  SER   A N   1 
ATOM   104  C CA  . SER   A 1 36  ? -2.04339  10.10668  4.63802   1.000 26.56342 ?  16  SER   A CA  1 
ATOM   105  C C   . SER   A 1 36  ? -0.91977  10.97101  5.18449   1.000 29.29902 ?  16  SER   A C   1 
ATOM   106  O O   . SER   A 1 36  ? 0.21556   10.83599  4.71675   1.000 35.72149 ?  16  SER   A O   1 
ATOM   107  C CB  . SER   A 1 36  ? -2.34688  10.55925  3.20105   1.000 29.59102 ?  16  SER   A CB  1 
ATOM   108  O OG  . SER   A 1 36  ? -2.78806  11.90612  3.17525   1.000 34.48229 ?  16  SER   A OG  1 
ATOM   109  N N   . GLU   A 1 37  ? -1.19028  11.84560  6.14780   1.000 31.80504 ?  17  GLU   A N   1 
ATOM   110  C CA  . GLU   A 1 37  ? -0.20360  12.77933  6.66884   1.000 26.98305 ?  17  GLU   A CA  1 
ATOM   111  C C   . GLU   A 1 37  ? 0.07958   12.44978  8.12583   1.000 24.46074 ?  17  GLU   A C   1 
ATOM   112  O O   . GLU   A 1 37  ? -0.84762  12.17098  8.89307   1.000 23.41757 ?  17  GLU   A O   1 
ATOM   113  C CB  . GLU   A 1 37  ? -0.69856  14.22288  6.54097   1.000 33.27820 ?  17  GLU   A CB  1 
ATOM   114  C CG  . GLU   A 1 37  ? -1.17387  14.59601  5.14313   1.000 39.15040 ?  17  GLU   A CG  1 
ATOM   115  C CD  . GLU   A 1 37  ? -0.12541  14.36408  4.07098   1.000 47.98090 ?  17  GLU   A CD  1 
ATOM   116  O OE1 . GLU   A 1 37  ? -0.51132  14.03537  2.93030   1.000 45.30495 ?  17  GLU   A OE1 1 
ATOM   117  O OE2 . GLU   A 1 37  ? 1.07882   14.53999  4.35450   1.000 52.24390 ?  17  GLU   A OE2 1 
ATOM   118  N N   . GLU   A 1 38  ? 1.35363   12.48312  8.50107   1.000 24.72275 ?  18  GLU   A N   1 
ATOM   119  C CA  . GLU   A 1 38  ? 1.71993   12.29303  9.89669   1.000 24.15114 ?  18  GLU   A CA  1 
ATOM   120  C C   . GLU   A 1 38  ? 1.13422   13.41793  10.74363  1.000 22.75147 ?  18  GLU   A C   1 
ATOM   121  O O   . GLU   A 1 38  ? 1.28900   14.59634  10.39292  1.000 23.72678 ?  18  GLU   A O   1 
ATOM   122  C CB  . GLU   A 1 38  ? 3.23719   12.26482  10.06773  1.000 22.00574 ?  18  GLU   A CB  1 
ATOM   123  C CG  . GLU   A 1 38  ? 3.67530   11.98500  11.50014  1.000 25.50426 ?  18  GLU   A CG  1 
ATOM   124  C CD  . GLU   A 1 38  ? 5.17982   11.91024  11.65330  1.000 27.32822 ?  18  GLU   A CD  1 
ATOM   125  O OE1 . GLU   A 1 38  ? 5.89232   12.25511  10.68854  1.000 25.19785 ?  18  GLU   A OE1 1 
ATOM   126  O OE2 . GLU   A 1 38  ? 5.64952   11.51778  12.74204  1.000 25.64266 ?  18  GLU   A OE2 1 
ATOM   127  N N   . PRO   A 1 39  ? 0.46023   13.10759  11.84526  1.000 24.41590 ?  19  PRO   A N   1 
ATOM   128  C CA  . PRO   A 1 39  ? 0.01644   14.15608  12.76119  1.000 23.53728 ?  19  PRO   A CA  1 
ATOM   129  C C   . PRO   A 1 39  ? 1.20906   14.87356  13.36431  1.000 22.15522 ?  19  PRO   A C   1 
ATOM   130  O O   . PRO   A 1 39  ? 2.21708   14.23792  13.70951  1.000 25.00225 ?  19  PRO   A O   1 
ATOM   131  C CB  . PRO   A 1 39  ? -0.76881  13.38388  13.83314  1.000 22.54604 ?  19  PRO   A CB  1 
ATOM   132  C CG  . PRO   A 1 39  ? -1.14278  12.09259  13.18156  1.000 19.21816 ?  19  PRO   A CG  1 
ATOM   133  C CD  . PRO   A 1 39  ? -0.00691  11.77567  12.25973  1.000 19.79186 ?  19  PRO   A CD  1 
ATOM   134  N N   . PRO   A 1 40  ? 1.14364   16.20057  13.48754  1.000 29.96752 ?  20  PRO   A N   1 
ATOM   135  C CA  . PRO   A 1 40  ? 2.24598   16.92452  14.14217  1.000 25.03997 ?  20  PRO   A CA  1 
ATOM   136  C C   . PRO   A 1 40  ? 2.46858   16.49358  15.57989  1.000 22.40821 ?  20  PRO   A C   1 
ATOM   137  O O   . PRO   A 1 40  ? 3.57795   16.65905  16.10353  1.000 31.17763 ?  20  PRO   A O   1 
ATOM   138  C CB  . PRO   A 1 40  ? 1.80973   18.39400  14.05014  1.000 18.82721 ?  20  PRO   A CB  1 
ATOM   139  C CG  . PRO   A 1 40  ? 0.79329   18.43725  12.95193  1.000 21.95082 ?  20  PRO   A CG  1 
ATOM   140  C CD  . PRO   A 1 40  ? 0.12276   17.10163  12.92770  1.000 21.87887 ?  20  PRO   A CD  1 
ATOM   141  N N   . GLU   A 1 41  ? 1.44264   15.93957  16.23235  1.000 29.40597 ?  21  GLU   A N   1 
ATOM   142  C CA  . GLU   A 1 41  ? 1.61063   15.42744  17.58810  1.000 28.31866 ?  21  GLU   A CA  1 
ATOM   143  C C   . GLU   A 1 41  ? 2.61740   14.28581  17.61930  1.000 26.54836 ?  21  GLU   A C   1 
ATOM   144  O O   . GLU   A 1 41  ? 3.46897   14.21961  18.51391  1.000 27.00516 ?  21  GLU   A O   1 
ATOM   145  C CB  . GLU   A 1 41  ? 0.26498   14.95842  18.14235  1.000 31.48832 ?  21  GLU   A CB  1 
ATOM   146  C CG  . GLU   A 1 41  ? -0.80370  16.03670  18.21657  1.000 33.81838 ?  21  GLU   A CG  1 
ATOM   147  C CD  . GLU   A 1 41  ? -1.69952  16.05228  16.99111  1.000 26.95373 ?  21  GLU   A CD  1 
ATOM   148  O OE1 . GLU   A 1 41  ? -1.16976  16.02760  15.86062  1.000 28.64735 ?  21  GLU   A OE1 1 
ATOM   149  O OE2 . GLU   A 1 41  ? -2.93774  16.08619  17.15939  1.000 33.28128 ?  21  GLU   A OE2 1 
ATOM   150  N N   . ILE   A 1 42  ? 2.53570   13.37902  16.64425  1.000 26.19594 ?  22  ILE   A N   1 
ATOM   151  C CA  . ILE   A 1 42  ? 3.43751   12.23329  16.61036  1.000 23.72781 ?  22  ILE   A CA  1 
ATOM   152  C C   . ILE   A 1 42  ? 4.85184   12.67542  16.25304  1.000 23.00366 ?  22  ILE   A C   1 
ATOM   153  O O   . ILE   A 1 42  ? 5.83523   12.14285  16.78238  1.000 21.19283 ?  22  ILE   A O   1 
ATOM   154  C CB  . ILE   A 1 42  ? 2.90361   11.17246  15.62943  1.000 22.80188 ?  22  ILE   A CB  1 
ATOM   155  C CG1 . ILE   A 1 42  ? 1.47114   10.77529  15.99646  1.000 21.42556 ?  22  ILE   A CG1 1 
ATOM   156  C CG2 . ILE   A 1 42  ? 3.80564   9.94347   15.61515  1.000 26.75853 ?  22  ILE   A CG2 1 
ATOM   157  C CD1 . ILE   A 1 42  ? 1.30142   10.32975  17.43538  1.000 25.69973 ?  22  ILE   A CD1 1 
ATOM   158  N N   . ARG   A 1 43  ? 4.97709   13.66197  15.36037  1.000 21.42635 ?  23  ARG   A N   1 
ATOM   159  C CA  . ARG   A 1 43  ? 6.29614   14.13452  14.94928  1.000 23.55822 ?  23  ARG   A CA  1 
ATOM   160  C C   . ARG   A 1 43  ? 7.05701   14.74869  16.11785  1.000 25.86715 ?  23  ARG   A C   1 
ATOM   161  O O   . ARG   A 1 43  ? 8.25858   14.50657  16.28150  1.000 26.34206 ?  23  ARG   A O   1 
ATOM   162  C CB  . ARG   A 1 43  ? 6.15584   15.14398  13.80918  1.000 22.64238 ?  23  ARG   A CB  1 
ATOM   163  C CG  . ARG   A 1 43  ? 7.47692   15.61132  13.21988  1.000 32.74434 ?  23  ARG   A CG  1 
ATOM   164  C CD  . ARG   A 1 43  ? 7.92859   14.69295  12.09896  1.000 39.64922 ?  23  ARG   A CD  1 
ATOM   165  N NE  . ARG   A 1 43  ? 8.59193   15.41520  11.02039  1.000 43.99074 ?  23  ARG   A NE  1 
ATOM   166  C CZ  . ARG   A 1 43  ? 8.07336   15.59496  9.81346   1.000 54.17414 ?  23  ARG   A CZ  1 
ATOM   167  N NH1 . ARG   A 1 43  ? 6.88333   15.11313  9.49433   1.000 40.91248 ?  23  ARG   A NH1 1 
ATOM   168  N NH2 . ARG   A 1 43  ? 8.76494   16.27671  8.90464   1.000 61.19781 ?  23  ARG   A NH2 1 
ATOM   169  N N   . ARG   A 1 44  ? 6.37416   15.54524  16.94271  1.000 24.06369 ?  24  ARG   A N   1 
ATOM   170  C CA  . ARG   A 1 44  ? 7.04038   16.18197  18.07418  1.000 29.37896 ?  24  ARG   A CA  1 
ATOM   171  C C   . ARG   A 1 44  ? 7.43885   15.16010  19.13011  1.000 28.49783 ?  24  ARG   A C   1 
ATOM   172  O O   . ARG   A 1 44  ? 8.50633   15.27803  19.74334  1.000 23.64025 ?  24  ARG   A O   1 
ATOM   173  C CB  . ARG   A 1 44  ? 6.13382   17.25015  18.68217  1.000 29.84334 ?  24  ARG   A CB  1 
ATOM   174  C CG  . ARG   A 1 44  ? 5.98059   18.49444  17.82923  1.000 36.49681 ?  24  ARG   A CG  1 
ATOM   175  C CD  . ARG   A 1 44  ? 5.32966   19.61701  18.61606  1.000 39.10610 ?  24  ARG   A CD  1 
ATOM   176  N NE  . ARG   A 1 44  ? 3.95857   19.85769  18.18353  1.000 43.51646 ?  24  ARG   A NE  1 
ATOM   177  C CZ  . ARG   A 1 44  ? 2.88917   19.30647  18.74138  1.000 42.14304 ?  24  ARG   A CZ  1 
ATOM   178  N NH1 . ARG   A 1 44  ? 2.99427   18.47053  19.76197  1.000 43.76635 ?  24  ARG   A NH1 1 
ATOM   179  N NH2 . ARG   A 1 44  ? 1.68370   19.60209  18.26405  1.000 33.47327 ?  24  ARG   A NH2 1 
ATOM   180  N N   . ILE   A 1 45  ? 6.59308   14.15276  19.35678  1.000 25.09723 ?  25  ILE   A N   1 
ATOM   181  C CA  . ILE   A 1 45  ? 6.89106   13.14173  20.36733  1.000 25.42092 ?  25  ILE   A CA  1 
ATOM   182  C C   . ILE   A 1 45  ? 8.13695   12.35568  19.98079  1.000 25.55225 ?  25  ILE   A C   1 
ATOM   183  O O   . ILE   A 1 45  ? 9.04483   12.15491  20.79651  1.000 26.35344 ?  25  ILE   A O   1 
ATOM   184  C CB  . ILE   A 1 45  ? 5.67971   12.21441  20.57319  1.000 25.86355 ?  25  ILE   A CB  1 
ATOM   185  C CG1 . ILE   A 1 45  ? 4.60594   12.91588  21.40483  1.000 24.13141 ?  25  ILE   A CG1 1 
ATOM   186  C CG2 . ILE   A 1 45  ? 6.10473   10.91456  21.24177  1.000 19.31174 ?  25  ILE   A CG2 1 
ATOM   187  C CD1 . ILE   A 1 45  ? 3.26752   12.22491  21.36830  1.000 23.95702 ?  25  ILE   A CD1 1 
ATOM   188  N N   . ARG   A 1 46  ? 8.20552   11.90823  18.72619  1.000 24.80281 ?  26  ARG   A N   1 
ATOM   189  C CA  . ARG   A 1 46  ? 9.30609   11.05000  18.30933  1.000 27.75031 ?  26  ARG   A CA  1 
ATOM   190  C C   . ARG   A 1 46  ? 10.60301  11.81438  18.08104  1.000 24.71330 ?  26  ARG   A C   1 
ATOM   191  O O   . ARG   A 1 46  ? 11.67049  11.19318  18.04021  1.000 28.13601 ?  26  ARG   A O   1 
ATOM   192  C CB  . ARG   A 1 46  ? 8.91873   10.27090  17.04952  1.000 20.28433 ?  26  ARG   A CB  1 
ATOM   193  C CG  . ARG   A 1 46  ? 8.83211   11.06994  15.76053  1.000 21.94130 ?  26  ARG   A CG  1 
ATOM   194  C CD  . ARG   A 1 46  ? 8.41559   10.13271  14.63167  1.000 30.73801 ?  26  ARG   A CD  1 
ATOM   195  N NE  . ARG   A 1 46  ? 8.05259   10.81302  13.39397  1.000 20.30464 ?  26  ARG   A NE  1 
ATOM   196  C CZ  . ARG   A 1 46  ? 8.90268   11.07684  12.41139  1.000 29.38354 ?  26  ARG   A CZ  1 
ATOM   197  N NH1 . ARG   A 1 46  ? 10.18691  10.77863  12.51175  1.000 27.06421 ?  26  ARG   A NH1 1 
ATOM   198  N NH2 . ARG   A 1 46  ? 8.45232   11.64866  11.29821  1.000 29.02629 ?  26  ARG   A NH2 1 
ATOM   199  N N   . THR   A 1 47  ? 10.54243  13.13626  17.94056  1.000 29.14868 ?  27  THR   A N   1 
ATOM   200  C CA  . THR   A 1 47  ? 11.73954  13.95828  17.83394  1.000 30.42988 ?  27  THR   A CA  1 
ATOM   201  C C   . THR   A 1 47  ? 12.09937  14.64507  19.14330  1.000 30.24882 ?  27  THR   A C   1 
ATOM   202  O O   . THR   A 1 47  ? 13.06749  15.41050  19.18030  1.000 27.04314 ?  27  THR   A O   1 
ATOM   203  C CB  . THR   A 1 47  ? 11.57126  15.00860  16.73085  1.000 21.51727 ?  27  THR   A CB  1 
ATOM   204  O OG1 . THR   A 1 47  ? 10.42513  15.82246  17.00892  1.000 28.17645 ?  27  THR   A OG1 1 
ATOM   205  C CG2 . THR   A 1 47  ? 11.40263  14.33568  15.37711  1.000 27.03977 ?  27  THR   A CG2 1 
ATOM   206  N N   . GLY   A 1 48  ? 11.35199  14.38844  20.21202  1.000 30.17281 ?  28  GLY   A N   1 
ATOM   207  C CA  . GLY   A 1 48  ? 11.63895  15.01784  21.49097  1.000 30.62033 ?  28  GLY   A CA  1 
ATOM   208  C C   . GLY   A 1 48  ? 11.45915  16.51986  21.48914  1.000 31.74751 ?  28  GLY   A C   1 
ATOM   209  O O   . GLY   A 1 48  ? 12.26034  17.23920  22.10064  1.000 25.62446 ?  28  GLY   A O   1 
ATOM   210  N N   . THR   A 1 49  ? 10.42611  17.01662  20.80502  1.000 23.62417 ?  29  THR   A N   1 
ATOM   211  C CA  . THR   A 1 49  ? 10.14931  18.44680  20.75430  1.000 28.68398 ?  29  THR   A CA  1 
ATOM   212  C C   . THR   A 1 49  ? 8.74682   18.76311  21.26639  1.000 35.60572 ?  29  THR   A C   1 
ATOM   213  O O   . THR   A 1 49  ? 8.09367   19.68931  20.78141  1.000 39.57344 ?  29  THR   A O   1 
ATOM   214  C CB  . THR   A 1 49  ? 10.34772  18.99469  19.33899  1.000 29.88084 ?  29  THR   A CB  1 
ATOM   215  O OG1 . THR   A 1 49  ? 9.48049   18.31333  18.42374  1.000 30.31297 ?  29  THR   A OG1 1 
ATOM   216  C CG2 . THR   A 1 49  ? 11.79589  18.82486  18.89474  1.000 27.31504 ?  29  THR   A CG2 1 
ATOM   217  N N   . VAL   A 1 50  ? 8.27342   18.00029  22.24197  1.000 36.42831 ?  30  VAL   A N   1 
ATOM   218  C CA  . VAL   A 1 50  ? 7.00565   18.31744  22.90045  1.000 40.09404 ?  30  VAL   A CA  1 
ATOM   219  C C   . VAL   A 1 50  ? 7.24137   19.46609  23.88064  1.000 46.20608 ?  30  VAL   A C   1 
ATOM   220  O O   . VAL   A 1 50  ? 8.22762   19.42929  24.63266  1.000 45.14939 ?  30  VAL   A O   1 
ATOM   221  C CB  . VAL   A 1 50  ? 6.45046   17.09130  23.61664  1.000 36.83505 ?  30  VAL   A CB  1 
ATOM   222  C CG1 . VAL   A 1 50  ? 5.14316   17.42787  24.32213  1.000 38.24259 ?  30  VAL   A CG1 1 
ATOM   223  C CG2 . VAL   A 1 50  ? 6.24763   15.95431  22.63063  1.000 31.51702 ?  30  VAL   A CG2 1 
ATOM   224  N N   . PRO   A 1 51  ? 6.39207   20.49356  23.88803  1.000 48.39083 ?  31  PRO   A N   1 
ATOM   225  C CA  . PRO   A 1 51  ? 6.57224   21.58568  24.85156  1.000 49.14734 ?  31  PRO   A CA  1 
ATOM   226  C C   . PRO   A 1 51  ? 6.57371   21.07467  26.28612  1.000 56.79109 ?  31  PRO   A C   1 
ATOM   227  O O   . PRO   A 1 51  ? 5.91329   20.08765  26.61935  1.000 60.04166 ?  31  PRO   A O   1 
ATOM   228  C CB  . PRO   A 1 51  ? 5.37037   22.49762  24.58028  1.000 50.49851 ?  31  PRO   A CB  1 
ATOM   229  C CG  . PRO   A 1 51  ? 5.02071   22.23516  23.15216  1.000 48.69258 ?  31  PRO   A CG  1 
ATOM   230  C CD  . PRO   A 1 51  ? 5.30834   20.77317  22.92981  1.000 47.28842 ?  31  PRO   A CD  1 
ATOM   231  N N   . ASP   A 1 52  ? 7.35120   21.75723  27.13108  1.000 58.87535 ?  32  ASP   A N   1 
ATOM   232  C CA  . ASP   A 1 52  ? 7.52303   21.44552  28.54992  1.000 56.45167 ?  32  ASP   A CA  1 
ATOM   233  C C   . ASP   A 1 52  ? 8.25848   20.12942  28.78872  1.000 58.91934 ?  32  ASP   A C   1 
ATOM   234  O O   . ASP   A 1 52  ? 8.23862   19.60700  29.90879  1.000 53.49636 ?  32  ASP   A O   1 
ATOM   235  C CB  . ASP   A 1 52  ? 6.18045   21.44914  29.29099  1.000 57.83787 ?  32  ASP   A CB  1 
ATOM   236  C CG  . ASP   A 1 52  ? 5.37093   22.69950  29.01189  1.000 63.91757 ?  32  ASP   A CG  1 
ATOM   237  O OD1 . ASP   A 1 52  ? 5.83895   23.54225  28.21686  1.000 60.70279 ?  32  ASP   A OD1 1 
ATOM   238  O OD2 . ASP   A 1 52  ? 4.27149   22.84253  29.58633  1.000 62.59055 ?  32  ASP   A OD2 1 
ATOM   239  N N   . LEU   A 1 53  ? 8.89911   19.58502  27.74450  1.000 54.58224 ?  33  LEU   A N   1 
ATOM   240  C CA  . LEU   A 1 53  ? 9.89526   18.51410  27.77514  1.000 48.87990 ?  33  LEU   A CA  1 
ATOM   241  C C   . LEU   A 1 53  ? 9.60841   17.43143  28.81097  1.000 50.25478 ?  33  LEU   A C   1 
ATOM   242  O O   . LEU   A 1 53  ? 10.17096  17.46580  29.91306  1.000 47.47448 ?  33  LEU   A O   1 
ATOM   243  C CB  . LEU   A 1 53  ? 11.28055  19.11112  28.03470  1.000 48.30616 ?  33  LEU   A CB  1 
ATOM   244  C CG  . LEU   A 1 53  ? 12.12073  19.50482  26.81682  1.000 49.04975 ?  33  LEU   A CG  1 
ATOM   245  C CD1 . LEU   A 1 53  ? 11.49743  20.67513  26.06962  1.000 51.59081 ?  33  LEU   A CD1 1 
ATOM   246  C CD2 . LEU   A 1 53  ? 13.54414  19.83695  27.23921  1.000 50.12222 ?  33  LEU   A CD2 1 
ATOM   247  N N   . PRO   A 1 54  ? 8.75466   16.45982  28.50544  1.000 49.62980 ?  34  PRO   A N   1 
ATOM   248  C CA  . PRO   A 1 54  ? 8.51619   15.36766  29.45233  1.000 40.90310 ?  34  PRO   A CA  1 
ATOM   249  C C   . PRO   A 1 54  ? 9.64685   14.35075  29.43472  1.000 43.06837 ?  34  PRO   A C   1 
ATOM   250  O O   . PRO   A 1 54  ? 10.27540  14.09442  28.40512  1.000 38.96239 ?  34  PRO   A O   1 
ATOM   251  C CB  . PRO   A 1 54  ? 7.20817   14.74818  28.94818  1.000 41.01075 ?  34  PRO   A CB  1 
ATOM   252  C CG  . PRO   A 1 54  ? 7.20488   15.05015  27.48786  1.000 37.45993 ?  34  PRO   A CG  1 
ATOM   253  C CD  . PRO   A 1 54  ? 7.83136   16.40864  27.35841  1.000 43.92956 ?  34  PRO   A CD  1 
ATOM   254  N N   . GLY   A 1 55  ? 9.90025   13.76841  30.60444  1.000 43.01125 ?  35  GLY   A N   1 
ATOM   255  C CA  . GLY   A 1 55  ? 10.97451  12.80489  30.75124  1.000 33.10291 ?  35  GLY   A CA  1 
ATOM   256  C C   . GLY   A 1 55  ? 11.98570  13.20527  31.80613  1.000 40.75538 ?  35  GLY   A C   1 
ATOM   257  O O   . GLY   A 1 55  ? 12.59899  14.27294  31.71365  1.000 47.71505 ?  35  GLY   A O   1 
ATOM   258  N N   . SER   A 1 56  ? 12.17473  12.35400  32.81120  1.000 39.72131 ?  36  SER   A N   1 
ATOM   259  C CA  . SER   A 1 56  ? 13.05793  12.68938  33.92004  1.000 43.96557 ?  36  SER   A CA  1 
ATOM   260  C C   . SER   A 1 56  ? 14.51735  12.66379  33.48114  1.000 45.86527 ?  36  SER   A C   1 
ATOM   261  O O   . SER   A 1 56  ? 14.96608  11.71679  32.82705  1.000 39.94696 ?  36  SER   A O   1 
ATOM   262  C CB  . SER   A 1 56  ? 12.84285  11.72010  35.08140  1.000 36.09476 ?  36  SER   A CB  1 
ATOM   263  O OG  . SER   A 1 56  ? 11.63023  11.99212  35.76097  1.000 42.00442 ?  36  SER   A OG  1 
ATOM   264  N N   . TYR   A 1 57  ? 15.25012  13.72295  33.83456  1.000 37.90375 ?  37  TYR   A N   1 
ATOM   265  C CA  . TYR   A 1 57  ? 16.70940  13.77619  33.70788  1.000 32.91710 ?  37  TYR   A CA  1 
ATOM   266  C C   . TYR   A 1 57  ? 17.16606  13.75068  32.24526  1.000 27.02503 ?  37  TYR   A C   1 
ATOM   267  O O   . TYR   A 1 57  ? 17.97490  12.91561  31.84012  1.000 32.38590 ?  37  TYR   A O   1 
ATOM   268  C CB  . TYR   A 1 57  ? 17.36799  12.65233  34.51437  1.000 40.65535 ?  37  TYR   A CB  1 
ATOM   269  C CG  . TYR   A 1 57  ? 17.31413  12.86558  36.01310  1.000 52.00888 ?  37  TYR   A CG  1 
ATOM   270  C CD1 . TYR   A 1 57  ? 18.03722  13.88673  36.61590  1.000 51.50275 ?  37  TYR   A CD1 1 
ATOM   271  C CD2 . TYR   A 1 57  ? 16.52964  12.05521  36.82258  1.000 49.11528 ?  37  TYR   A CD2 1 
ATOM   272  C CE1 . TYR   A 1 57  ? 17.99064  14.08481  37.98525  1.000 46.02054 ?  37  TYR   A CE1 1 
ATOM   273  C CE2 . TYR   A 1 57  ? 16.47714  12.24436  38.19111  1.000 47.54996 ?  37  TYR   A CE2 1 
ATOM   274  C CZ  . TYR   A 1 57  ? 17.20818  13.26112  38.76699  1.000 43.55475 ?  37  TYR   A CZ  1 
ATOM   275  O OH  . TYR   A 1 57  ? 17.15544  13.45402  40.12841  1.000 43.99866 ?  37  TYR   A OH  1 
ATOM   276  N N   . GLY   A 1 58  ? 16.63656  14.68065  31.45456  1.000 31.43920 ?  38  GLY   A N   1 
ATOM   277  C CA  . GLY   A 1 58  ? 17.22214  14.99968  30.16456  1.000 39.98449 ?  38  GLY   A CA  1 
ATOM   278  C C   . GLY   A 1 58  ? 17.07636  13.96473  29.07037  1.000 39.11103 ?  38  GLY   A C   1 
ATOM   279  O O   . GLY   A 1 58  ? 17.91436  13.91948  28.16285  1.000 38.85358 ?  38  GLY   A O   1 
ATOM   280  N N   . GLN   A 1 59  ? 16.03797  13.13338  29.11873  1.000 35.35598 ?  39  GLN   A N   1 
ATOM   281  C CA  . GLN   A 1 59  ? 15.74123  12.23265  28.01435  1.000 32.09419 ?  39  GLN   A CA  1 
ATOM   282  C C   . GLN   A 1 59  ? 14.23623  12.21420  27.79325  1.000 32.52045 ?  39  GLN   A C   1 
ATOM   283  O O   . GLN   A 1 59  ? 13.45712  12.60397  28.66647  1.000 34.55559 ?  39  GLN   A O   1 
ATOM   284  C CB  . GLN   A 1 59  ? 16.28083  10.81344  28.26603  1.000 33.79178 ?  39  GLN   A CB  1 
ATOM   285  C CG  . GLN   A 1 59  ? 15.90035  10.19681  29.60314  1.000 33.59685 ?  39  GLN   A CG  1 
ATOM   286  C CD  . GLN   A 1 59  ? 14.47744  9.67678   29.61837  1.000 29.61965 ?  39  GLN   A CD  1 
ATOM   287  O OE1 . GLN   A 1 59  ? 14.13784  8.75040   28.88117  1.000 27.55388 ?  39  GLN   A OE1 1 
ATOM   288  N NE2 . GLN   A 1 59  ? 13.63601  10.27340  30.45242  1.000 30.60373 ?  39  GLN   A NE2 1 
ATOM   289  N N   . TYR   A 1 60  ? 13.82753  11.76158  26.60770  1.000 32.08225 ?  40  TYR   A N   1 
ATOM   290  C CA  . TYR   A 1 60  ? 12.41107  11.71328  26.26897  1.000 32.12062 ?  40  TYR   A CA  1 
ATOM   291  C C   . TYR   A 1 60  ? 11.94074  10.32301  25.86265  1.000 28.47348 ?  40  TYR   A C   1 
ATOM   292  O O   . TYR   A 1 60  ? 10.84244  10.19520  25.30904  1.000 27.55265 ?  40  TYR   A O   1 
ATOM   293  C CB  . TYR   A 1 60  ? 12.08206  12.71659  25.15802  1.000 29.04615 ?  40  TYR   A CB  1 
ATOM   294  C CG  . TYR   A 1 60  ? 12.80107  12.48519  23.84763  1.000 32.31390 ?  40  TYR   A CG  1 
ATOM   295  C CD1 . TYR   A 1 60  ? 14.07411  12.99721  23.62861  1.000 33.67653 ?  40  TYR   A CD1 1 
ATOM   296  C CD2 . TYR   A 1 60  ? 12.19952  11.76645  22.82320  1.000 28.77645 ?  40  TYR   A CD2 1 
ATOM   297  C CE1 . TYR   A 1 60  ? 14.72823  12.79457  22.42677  1.000 32.33262 ?  40  TYR   A CE1 1 
ATOM   298  C CE2 . TYR   A 1 60  ? 12.84573  11.55781  21.61986  1.000 28.71447 ?  40  TYR   A CE2 1 
ATOM   299  C CZ  . TYR   A 1 60  ? 14.10906  12.07348  21.42694  1.000 29.22495 ?  40  TYR   A CZ  1 
ATOM   300  O OH  . TYR   A 1 60  ? 14.75584  11.86773  20.23018  1.000 38.20026 ?  40  TYR   A OH  1 
ATOM   301  N N   . PHE   A 1 61  ? 12.73076  9.27815   26.11956  1.000 26.72457 ?  41  PHE   A N   1 
ATOM   302  C CA  . PHE   A 1 61  ? 12.26708  7.92919   25.81149  1.000 25.30636 ?  41  PHE   A CA  1 
ATOM   303  C C   . PHE   A 1 61  ? 11.12763  7.51527   26.73320  1.000 24.93200 ?  41  PHE   A C   1 
ATOM   304  O O   . PHE   A 1 61  ? 10.11748  6.96574   26.27863  1.000 24.13167 ?  41  PHE   A O   1 
ATOM   305  C CB  . PHE   A 1 61  ? 13.41154  6.92379   25.91092  1.000 27.87162 ?  41  PHE   A CB  1 
ATOM   306  C CG  . PHE   A 1 61  ? 12.95245  5.49432   25.84132  1.000 32.49173 ?  41  PHE   A CG  1 
ATOM   307  C CD1 . PHE   A 1 61  ? 12.26986  5.02507   24.72960  1.000 28.91958 ?  41  PHE   A CD1 1 
ATOM   308  C CD2 . PHE   A 1 61  ? 13.17543  4.62788   26.89839  1.000 28.03086 ?  41  PHE   A CD2 1 
ATOM   309  C CE1 . PHE   A 1 61  ? 11.83324  3.71524   24.66741  1.000 33.67082 ?  41  PHE   A CE1 1 
ATOM   310  C CE2 . PHE   A 1 61  ? 12.74338  3.31613   26.84101  1.000 33.75175 ?  41  PHE   A CE2 1 
ATOM   311  C CZ  . PHE   A 1 61  ? 12.07195  2.85926   25.72363  1.000 29.62334 ?  41  PHE   A CZ  1 
ATOM   312  N N   . THR   A 1 62  ? 11.27975  7.75846   28.03752  1.000 25.54669 ?  42  THR   A N   1 
ATOM   313  C CA  . THR   A 1 62  ? 10.24263  7.37142   28.98883  1.000 23.61937 ?  42  THR   A CA  1 
ATOM   314  C C   . THR   A 1 62  ? 8.92511   8.07106   28.68241  1.000 21.29956 ?  42  THR   A C   1 
ATOM   315  O O   . THR   A 1 62  ? 7.85375   7.45959   28.76821  1.000 24.92068 ?  42  THR   A O   1 
ATOM   316  C CB  . THR   A 1 62  ? 10.69471  7.68210   30.41480  1.000 26.74932 ?  42  THR   A CB  1 
ATOM   317  O OG1 . THR   A 1 62  ? 10.89235  9.09487   30.55833  1.000 18.91225 ?  42  THR   A OG1 1 
ATOM   318  C CG2 . THR   A 1 62  ? 11.99738  6.96118   30.72674  1.000 21.34675 ?  42  THR   A CG2 1 
ATOM   319  N N   . ALA   A 1 63  ? 8.98298   9.35382   28.32023  1.000 21.34830 ?  43  ALA   A N   1 
ATOM   320  C CA  . ALA   A 1 63  ? 7.77220   10.04970  27.90065  1.000 24.69769 ?  43  ALA   A CA  1 
ATOM   321  C C   . ALA   A 1 63  ? 7.22843   9.46171   26.60547  1.000 20.45742 ?  43  ALA   A C   1 
ATOM   322  O O   . ALA   A 1 63  ? 6.01079   9.32706   26.43682  1.000 20.00614 ?  43  ALA   A O   1 
ATOM   323  C CB  . ALA   A 1 63  ? 8.05515   11.54085  27.73755  1.000 30.90666 ?  43  ALA   A CB  1 
ATOM   324  N N   . TRP   A 1 64  ? 8.12218   9.10336   25.68015  1.000 20.14007 ?  44  TRP   A N   1 
ATOM   325  C CA  . TRP   A 1 64  ? 7.70517   8.46144   24.43784  1.000 19.70166 ?  44  TRP   A CA  1 
ATOM   326  C C   . TRP   A 1 64  ? 7.03366   7.12297   24.71399  1.000 22.01489 ?  44  TRP   A C   1 
ATOM   327  O O   . TRP   A 1 64  ? 6.03824   6.77189   24.06882  1.000 18.59356 ?  44  TRP   A O   1 
ATOM   328  C CB  . TRP   A 1 64  ? 8.92102   8.28509   23.52802  1.000 22.17023 ?  44  TRP   A CB  1 
ATOM   329  C CG  . TRP   A 1 64  ? 8.62522   7.93612   22.10067  1.000 17.34339 ?  44  TRP   A CG  1 
ATOM   330  C CD1 . TRP   A 1 64  ? 7.40819   7.66157   21.54771  1.000 20.26210 ?  44  TRP   A CD1 1 
ATOM   331  C CD2 . TRP   A 1 64  ? 9.57971   7.83790   21.03819  1.000 23.30233 ?  44  TRP   A CD2 1 
ATOM   332  N NE1 . TRP   A 1 64  ? 7.54800   7.39223   20.20667  1.000 18.51440 ?  44  TRP   A NE1 1 
ATOM   333  C CE2 . TRP   A 1 64  ? 8.87207   7.49507   19.86980  1.000 18.49344 ?  44  TRP   A CE2 1 
ATOM   334  C CE3 . TRP   A 1 64  ? 10.96655  8.00516   20.96307  1.000 19.38506 ?  44  TRP   A CE3 1 
ATOM   335  C CZ2 . TRP   A 1 64  ? 9.50372   7.31542   18.64153  1.000 21.89993 ?  44  TRP   A CZ2 1 
ATOM   336  C CZ3 . TRP   A 1 64  ? 11.59157  7.82758   19.74298  1.000 22.19610 ?  44  TRP   A CZ3 1 
ATOM   337  C CH2 . TRP   A 1 64  ? 10.86055  7.48675   18.59845  1.000 25.91737 ?  44  TRP   A CH2 1 
ATOM   338  N N   . ASP   A 1 65  ? 7.56173   6.36610   25.67814  1.000 20.71454 ?  45  ASP   A N   1 
ATOM   339  C CA  . ASP   A 1 65  ? 6.96194   5.08288   26.02419  1.000 18.74835 ?  45  ASP   A CA  1 
ATOM   340  C C   . ASP   A 1 65  ? 5.55884   5.26521   26.58895  1.000 20.29966 ?  45  ASP   A C   1 
ATOM   341  O O   . ASP   A 1 65  ? 4.63948   4.51258   26.24557  1.000 22.94441 ?  45  ASP   A O   1 
ATOM   342  C CB  . ASP   A 1 65  ? 7.84886   4.34467   27.02506  1.000 22.86817 ?  45  ASP   A CB  1 
ATOM   343  C CG  . ASP   A 1 65  ? 7.66627   2.84437   26.96464  1.000 26.76099 ?  45  ASP   A CG  1 
ATOM   344  O OD1 . ASP   A 1 65  ? 8.12736   2.23601   25.97924  1.000 27.14743 ?  45  ASP   A OD1 1 
ATOM   345  O OD2 . ASP   A 1 65  ? 7.06106   2.27505   27.89628  1.000 21.16242 ?  45  ASP   A OD2 1 
ATOM   346  N N   . PHE   A 1 66  ? 5.37462   6.26053   27.45911  1.000 22.49801 ?  46  PHE   A N   1 
ATOM   347  C CA  . PHE   A 1 66  ? 4.05196   6.51270   28.02062  1.000 22.43932 ?  46  PHE   A CA  1 
ATOM   348  C C   . PHE   A 1 66  ? 3.10634   7.08649   26.97349  1.000 20.72660 ?  46  PHE   A C   1 
ATOM   349  O O   . PHE   A 1 66  ? 1.92343   6.73034   26.93876  1.000 22.63427 ?  46  PHE   A O   1 
ATOM   350  C CB  . PHE   A 1 66  ? 4.16065   7.45477   29.21914  1.000 20.73176 ?  46  PHE   A CB  1 
ATOM   351  C CG  . PHE   A 1 66  ? 4.44356   6.75478   30.51655  1.000 21.12891 ?  46  PHE   A CG  1 
ATOM   352  C CD1 . PHE   A 1 66  ? 5.72837   6.34758   30.83348  1.000 21.21742 ?  46  PHE   A CD1 1 
ATOM   353  C CD2 . PHE   A 1 66  ? 3.42425   6.50509   31.42067  1.000 21.06893 ?  46  PHE   A CD2 1 
ATOM   354  C CE1 . PHE   A 1 66  ? 5.99155   5.70459   32.02634  1.000 18.75810 ?  46  PHE   A CE1 1 
ATOM   355  C CE2 . PHE   A 1 66  ? 3.68189   5.86129   32.61703  1.000 24.50870 ?  46  PHE   A CE2 1 
ATOM   356  C CZ  . PHE   A 1 66  ? 4.96734   5.46083   32.92010  1.000 18.33332 ?  46  PHE   A CZ  1 
ATOM   357  N N   . SER   A 1 67  ? 3.60849   7.97676   26.11421  1.000 20.75554 ?  47  SER   A N   1 
ATOM   358  C CA  . SER   A 1 67  ? 2.76664   8.57288   25.08157  1.000 23.12316 ?  47  SER   A CA  1 
ATOM   359  C C   . SER   A 1 67  ? 2.20745   7.50691   24.14652  1.000 20.46960 ?  47  SER   A C   1 
ATOM   360  O O   . SER   A 1 67  ? 1.01136   7.50257   23.83687  1.000 23.12446 ?  47  SER   A O   1 
ATOM   361  C CB  . SER   A 1 67  ? 3.56328   9.61567   24.29591  1.000 19.65307 ?  47  SER   A CB  1 
ATOM   362  O OG  . SER   A 1 67  ? 3.79998   10.77423  25.07651  1.000 32.24019 ?  47  SER   A OG  1 
ATOM   363  N N   . ASN   A 1 68  ? 3.06142   6.58384   23.69720  1.000 13.23841 ?  48  ASN   A N   1 
ATOM   364  C CA  . ASN   A 1 68  ? 2.62700   5.55818   22.75309  1.000 20.29573 ?  48  ASN   A CA  1 
ATOM   365  C C   . ASN   A 1 68  ? 1.65137   4.57732   23.39061  1.000 19.30709 ?  48  ASN   A C   1 
ATOM   366  O O   . ASN   A 1 68  ? 0.64002   4.21342   22.77873  1.000 20.74868 ?  48  ASN   A O   1 
ATOM   367  C CB  . ASN   A 1 68  ? 3.84011   4.80932   22.20105  1.000 17.29258 ?  48  ASN   A CB  1 
ATOM   368  C CG  . ASN   A 1 68  ? 3.45077   3.68278   21.26244  1.000 16.86353 ?  48  ASN   A CG  1 
ATOM   369  O OD1 . ASN   A 1 68  ? 3.00746   3.91683   20.13908  1.000 22.73103 ?  48  ASN   A OD1 1 
ATOM   370  N ND2 . ASN   A 1 68  ? 3.60566   2.44745   21.72783  1.000 16.81868 ?  48  ASN   A ND2 1 
ATOM   371  N N   . SER   A 1 69  ? 1.93926   4.13025   24.61242  1.000 16.41153 ?  49  SER   A N   1 
ATOM   372  C CA  . SER   A 1 69  ? 1.14027   3.06652   25.20847  1.000 17.16031 ?  49  SER   A CA  1 
ATOM   373  C C   . SER   A 1 69  ? -0.17351  3.58803   25.77702  1.000 19.14589 ?  49  SER   A C   1 
ATOM   374  O O   . SER   A 1 69  ? -1.20147  2.90627   25.69151  1.000 20.10860 ?  49  SER   A O   1 
ATOM   375  C CB  . SER   A 1 69  ? 1.94468   2.35774   26.29462  1.000 18.04971 ?  49  SER   A CB  1 
ATOM   376  O OG  . SER   A 1 69  ? 2.52949   3.28597   27.19124  1.000 18.33936 ?  49  SER   A OG  1 
ATOM   377  N N   . ILE   A 1 70  ? -0.16496  4.78630   26.36264  1.000 16.16770 ?  50  ILE   A N   1 
ATOM   378  C CA  . ILE   A 1 70  ? -1.38838  5.30744   26.96143  1.000 16.81046 ?  50  ILE   A CA  1 
ATOM   379  C C   . ILE   A 1 70  ? -2.38714  5.70019   25.88047  1.000 19.55711 ?  50  ILE   A C   1 
ATOM   380  O O   . ILE   A 1 70  ? -3.58617  5.42967   26.00518  1.000 18.09238 ?  50  ILE   A O   1 
ATOM   381  C CB  . ILE   A 1 70  ? -1.06950  6.47866   27.90678  1.000 20.80214 ?  50  ILE   A CB  1 
ATOM   382  C CG1 . ILE   A 1 70  ? -0.33758  5.95539   29.14567  1.000 23.87916 ?  50  ILE   A CG1 1 
ATOM   383  C CG2 . ILE   A 1 70  ? -2.34747  7.20885   28.30478  1.000 19.42873 ?  50  ILE   A CG2 1 
ATOM   384  C CD1 . ILE   A 1 70  ? -0.49542  6.81582   30.37067  1.000 30.15218 ?  50  ILE   A CD1 1 
ATOM   385  N N   . VAL   A 1 71  ? -1.91356  6.31537   24.79205  1.000 15.48396 ?  51  VAL   A N   1 
ATOM   386  C CA  . VAL   A 1 71  ? -2.81904  6.68039   23.70384  1.000 15.73658 ?  51  VAL   A CA  1 
ATOM   387  C C   . VAL   A 1 71  ? -3.41160  5.43035   23.06270  1.000 16.44203 ?  51  VAL   A C   1 
ATOM   388  O O   . VAL   A 1 71  ? -4.55949  5.43683   22.60017  1.000 19.09867 ?  51  VAL   A O   1 
ATOM   389  C CB  . VAL   A 1 71  ? -2.10016  7.57272   22.67058  1.000 22.53655 ?  51  VAL   A CB  1 
ATOM   390  C CG1 . VAL   A 1 71  ? -1.19821  6.75235   21.75193  1.000 16.89615 ?  51  VAL   A CG1 1 
ATOM   391  C CG2 . VAL   A 1 71  ? -3.11583  8.36132   21.85482  1.000 19.49917 ?  51  VAL   A CG2 1 
ATOM   392  N N   . ARG   A 1 72  ? -2.64790  4.33479   23.04029  1.000 14.45255 ?  52  ARG   A N   1 
ATOM   393  C CA  . ARG   A 1 72  ? -3.16593  3.07450   22.51892  1.000 17.32812 ?  52  ARG   A CA  1 
ATOM   394  C C   . ARG   A 1 72  ? -4.24226  2.50993   23.43317  1.000 16.83008 ?  52  ARG   A C   1 
ATOM   395  O O   . ARG   A 1 72  ? -5.35417  2.20151   22.98834  1.000 16.43277 ?  52  ARG   A O   1 
ATOM   396  C CB  . ARG   A 1 72  ? -2.02522  2.06992   22.35544  1.000 17.57126 ?  52  ARG   A CB  1 
ATOM   397  C CG  . ARG   A 1 72  ? -2.47743  0.65434   22.04104  1.000 25.25789 ?  52  ARG   A CG  1 
ATOM   398  C CD  . ARG   A 1 72  ? -1.40849  -0.35419  22.41662  1.000 19.18374 ?  52  ARG   A CD  1 
ATOM   399  N NE  . ARG   A 1 72  ? -1.18197  -0.41144  23.85458  1.000 20.86661 ?  52  ARG   A NE  1 
ATOM   400  C CZ  . ARG   A 1 72  ? 0.01589   -0.45235  24.42083  1.000 23.81294 ?  52  ARG   A CZ  1 
ATOM   401  N NH1 . ARG   A 1 72  ? 1.12395   -0.43026  23.69719  1.000 15.74924 ?  52  ARG   A NH1 1 
ATOM   402  N NH2 . ARG   A 1 72  ? 0.10445   -0.51690  25.74601  1.000 15.69258 ?  52  ARG   A NH2 1 
ATOM   403  N N   . ASP   A 1 73  ? -3.92533  2.37029   24.72087  1.000 17.86694 ?  53  ASP   A N   1 
ATOM   404  C CA  . ASP   A 1 73  ? -4.88506  1.81282   25.66289  1.000 16.11448 ?  53  ASP   A CA  1 
ATOM   405  C C   . ASP   A 1 73  ? -6.06057  2.75704   25.88742  1.000 17.23950 ?  53  ASP   A C   1 
ATOM   406  O O   . ASP   A 1 73  ? -7.17289  2.29965   26.17633  1.000 16.41589 ?  53  ASP   A O   1 
ATOM   407  C CB  . ASP   A 1 73  ? -4.17868  1.48178   26.97699  1.000 15.54724 ?  53  ASP   A CB  1 
ATOM   408  C CG  . ASP   A 1 73  ? -3.08345  0.43740   26.80380  1.000 17.69223 ?  53  ASP   A CG  1 
ATOM   409  O OD1 . ASP   A 1 73  ? -3.08432  -0.27128  25.77628  1.000 18.47904 ?  53  ASP   A OD1 1 
ATOM   410  O OD2 . ASP   A 1 73  ? -2.22073  0.32011   27.69779  1.000 22.81525 ?  53  ASP   A OD2 1 
ATOM   411  N N   . TYR   A 1 74  ? -5.83543  4.06803   25.75804  1.000 15.34142 ?  54  TYR   A N   1 
ATOM   412  C CA  . TYR   A 1 74  ? -6.94174  5.02136   25.74839  1.000 13.04237 ?  54  TYR   A CA  1 
ATOM   413  C C   . TYR   A 1 74  ? -7.88468  4.74564   24.58437  1.000 13.42859 ?  54  TYR   A C   1 
ATOM   414  O O   . TYR   A 1 74  ? -9.11064  4.75191   24.74682  1.000 17.95346 ?  54  TYR   A O   1 
ATOM   415  C CB  . TYR   A 1 74  ? -6.39652  6.44908   25.67781  1.000 15.37698 ?  54  TYR   A CB  1 
ATOM   416  C CG  . TYR   A 1 74  ? -7.43881  7.54150   25.74471  1.000 17.43405 ?  54  TYR   A CG  1 
ATOM   417  C CD1 . TYR   A 1 74  ? -8.37186  7.58105   26.77072  1.000 16.80873 ?  54  TYR   A CD1 1 
ATOM   418  C CD2 . TYR   A 1 74  ? -7.47593  8.54546   24.78675  1.000 17.45524 ?  54  TYR   A CD2 1 
ATOM   419  C CE1 . TYR   A 1 74  ? -9.31797  8.58429   26.83706  1.000 16.59028 ?  54  TYR   A CE1 1 
ATOM   420  C CE2 . TYR   A 1 74  ? -8.41671  9.55178   24.84372  1.000 12.46114 ?  54  TYR   A CE2 1 
ATOM   421  C CZ  . TYR   A 1 74  ? -9.33529  9.56746   25.86936  1.000 19.81494 ?  54  TYR   A CZ  1 
ATOM   422  O OH  . TYR   A 1 74  ? -10.27324 10.57201  25.92483  1.000 15.15213 ?  54  TYR   A OH  1 
ATOM   423  N N   . ALA   A 1 75  ? -7.32405  4.49710   23.39679  1.000 12.44939 ?  55  ALA   A N   1 
ATOM   424  C CA  . ALA   A 1 75  ? -8.14590  4.16345   22.23815  1.000 16.12522 ?  55  ALA   A CA  1 
ATOM   425  C C   . ALA   A 1 75  ? -8.93078  2.87797   22.45929  1.000 18.40880 ?  55  ALA   A C   1 
ATOM   426  O O   . ALA   A 1 75  ? -10.04414 2.73252   21.94112  1.000 13.40745 ?  55  ALA   A O   1 
ATOM   427  C CB  . ALA   A 1 75  ? -7.27009  4.04216   20.99086  1.000 11.86147 ?  55  ALA   A CB  1 
ATOM   428  N N   . MET   A 1 76  ? -8.37174  1.93740   23.22270  1.000 13.77951 ?  56  MET   A N   1 
ATOM   429  C CA  . MET   A 1 76  ? -9.09601  0.70751   23.51912  1.000 20.13683 ?  56  MET   A CA  1 
ATOM   430  C C   . MET   A 1 76  ? -10.27954 0.98085   24.43874  1.000 17.15370 ?  56  MET   A C   1 
ATOM   431  O O   . MET   A 1 76  ? -11.35806 0.40102   24.26152  1.000 15.90982 ?  56  MET   A O   1 
ATOM   432  C CB  . MET   A 1 76  ? -8.14971  -0.31813  24.14161  1.000 18.16792 ?  56  MET   A CB  1 
ATOM   433  C CG  . MET   A 1 76  ? -7.25161  -1.01297  23.12976  1.000 19.70161 ?  56  MET   A CG  1 
ATOM   434  S SD  . MET   A 1 76  ? -6.61160  -2.59257  23.71443  1.000 25.24521 ?  56  MET   A SD  1 
ATOM   435  C CE  . MET   A 1 76  ? -5.71118  -2.07869  25.17451  1.000 18.82654 ?  56  MET   A CE  1 
ATOM   436  N N   . ASN   A 1 77  ? -10.09549 1.86354   25.42603  1.000 13.98517 ?  57  ASN   A N   1 
ATOM   437  C CA  . ASN   A 1 77  ? -11.20618 2.26077   26.28539  1.000 15.36918 ?  57  ASN   A CA  1 
ATOM   438  C C   . ASN   A 1 77  ? -12.29973 2.95551   25.48531  1.000 15.85102 ?  57  ASN   A C   1 
ATOM   439  O O   . ASN   A 1 77  ? -13.49069 2.69568   25.69230  1.000 15.61061 ?  57  ASN   A O   1 
ATOM   440  C CB  . ASN   A 1 77  ? -10.70810 3.17884   27.40378  1.000 12.29718 ?  57  ASN   A CB  1 
ATOM   441  C CG  . ASN   A 1 77  ? -9.84115  2.45771   28.41421  1.000 17.27773 ?  57  ASN   A CG  1 
ATOM   442  O OD1 . ASN   A 1 77  ? -9.47594  1.29828   28.22343  1.000 18.73188 ?  57  ASN   A OD1 1 
ATOM   443  N ND2 . ASN   A 1 77  ? -9.51138  3.14293   29.50364  1.000 15.81111 ?  57  ASN   A ND2 1 
ATOM   444  N N   . LEU   A 1 78  ? -11.91297 3.84045   24.56316  1.000 12.15744 ?  58  LEU   A N   1 
ATOM   445  C CA  . LEU   A 1 78  ? -12.89982 4.62634   23.83056  1.000 16.64745 ?  58  LEU   A CA  1 
ATOM   446  C C   . LEU   A 1 78  ? -13.77009 3.74730   22.94253  1.000 16.64933 ?  58  LEU   A C   1 
ATOM   447  O O   . LEU   A 1 78  ? -14.96362 4.02132   22.77011  1.000 17.69106 ?  58  LEU   A O   1 
ATOM   448  C CB  . LEU   A 1 78  ? -12.20091 5.70255   23.00293  1.000 12.38985 ?  58  LEU   A CB  1 
ATOM   449  C CG  . LEU   A 1 78  ? -11.69242 6.90913   23.79075  1.000 13.60588 ?  58  LEU   A CG  1 
ATOM   450  C CD1 . LEU   A 1 78  ? -10.87036 7.81609   22.89248  1.000 14.00686 ?  58  LEU   A CD1 1 
ATOM   451  C CD2 . LEU   A 1 78  ? -12.85296 7.67084   24.41353  1.000 10.63242 ?  58  LEU   A CD2 1 
ATOM   452  N N   . TYR   A 1 79  ? -13.19525 2.69122   22.36238  1.000 14.02860 ?  59  TYR   A N   1 
ATOM   453  C CA  . TYR   A 1 79  ? -14.00233 1.79302   21.54355  1.000 19.73610 ?  59  TYR   A CA  1 
ATOM   454  C C   . TYR   A 1 79  ? -15.00510 1.02490   22.39501  1.000 18.57170 ?  59  TYR   A C   1 
ATOM   455  O O   . TYR   A 1 79  ? -16.18238 0.91216   22.03424  1.000 16.85602 ?  59  TYR   A O   1 
ATOM   456  C CB  . TYR   A 1 79  ? -13.12348 0.81612   20.76511  1.000 21.69549 ?  59  TYR   A CB  1 
ATOM   457  C CG  . TYR   A 1 79  ? -13.96734 -0.15480  19.97601  1.000 18.91949 ?  59  TYR   A CG  1 
ATOM   458  C CD1 . TYR   A 1 79  ? -14.67021 0.26700   18.85586  1.000 17.59985 ?  59  TYR   A CD1 1 
ATOM   459  C CD2 . TYR   A 1 79  ? -14.10637 -1.47711  20.37829  1.000 17.69304 ?  59  TYR   A CD2 1 
ATOM   460  C CE1 . TYR   A 1 79  ? -15.46226 -0.60439  18.13970  1.000 17.98858 ?  59  TYR   A CE1 1 
ATOM   461  C CE2 . TYR   A 1 79  ? -14.90042 -2.35906  19.66623  1.000 21.17280 ?  59  TYR   A CE2 1 
ATOM   462  C CZ  . TYR   A 1 79  ? -15.57552 -1.91560  18.54768  1.000 18.78021 ?  59  TYR   A CZ  1 
ATOM   463  O OH  . TYR   A 1 79  ? -16.36971 -2.78195  17.83165  1.000 20.58794 ?  59  TYR   A OH  1 
ATOM   464  N N   . GLN   A 1 80  ? -14.55113 0.47137   23.52285  1.000 21.28191 ?  60  GLN   A N   1 
ATOM   465  C CA  . GLN   A 1 80  ? -15.45982 -0.25859  24.40031  1.000 24.06314 ?  60  GLN   A CA  1 
ATOM   466  C C   . GLN   A 1 80  ? -16.53203 0.65730   24.97341  1.000 21.94459 ?  60  GLN   A C   1 
ATOM   467  O O   . GLN   A 1 80  ? -17.64486 0.20390   25.26444  1.000 24.39287 ?  60  GLN   A O   1 
ATOM   468  C CB  . GLN   A 1 80  ? -14.67763 -0.93935  25.52477  1.000 21.66573 ?  60  GLN   A CB  1 
ATOM   469  C CG  . GLN   A 1 80  ? -13.70290 -2.02036  25.05723  1.000 21.49581 ?  60  GLN   A CG  1 
ATOM   470  C CD  . GLN   A 1 80  ? -14.33867 -3.08329  24.16785  1.000 23.89102 ?  60  GLN   A CD  1 
ATOM   471  O OE1 . GLN   A 1 80  ? -15.54619 -3.32240  24.21676  1.000 24.98595 ?  60  GLN   A OE1 1 
ATOM   472  N NE2 . GLN   A 1 80  ? -13.51769 -3.72317  23.34273  1.000 20.43848 ?  60  GLN   A NE2 1 
ATOM   473  N N   . LEU   A 1 81  ? -16.21936 1.94444   25.14228  1.000 16.51979 ?  61  LEU   A N   1 
ATOM   474  C CA  . LEU   A 1 81  ? -17.24560 2.90446   25.53291  1.000 20.83527 ?  61  LEU   A CA  1 
ATOM   475  C C   . LEU   A 1 81  ? -18.20564 3.17495   24.38146  1.000 18.95897 ?  61  LEU   A C   1 
ATOM   476  O O   . LEU   A 1 81  ? -19.40588 3.37568   24.60117  1.000 21.00927 ?  61  LEU   A O   1 
ATOM   477  C CB  . LEU   A 1 81  ? -16.59857 4.20342   26.01428  1.000 21.90108 ?  61  LEU   A CB  1 
ATOM   478  C CG  . LEU   A 1 81  ? -15.85378 4.14329   27.34960  1.000 21.79914 ?  61  LEU   A CG  1 
ATOM   479  C CD1 . LEU   A 1 81  ? -14.92550 5.33814   27.50440  1.000 15.30970 ?  61  LEU   A CD1 1 
ATOM   480  C CD2 . LEU   A 1 81  ? -16.83782 4.06986   28.50641  1.000 32.14432 ?  61  LEU   A CD2 1 
ATOM   481  N N   . THR   A 1 82  ? -17.69389 3.18817   23.14670  1.000 19.01068 ?  62  THR   A N   1 
ATOM   482  C CA  . THR   A 1 82  ? -18.56847 3.30523   21.98375  1.000 17.99100 ?  62  THR   A CA  1 
ATOM   483  C C   . THR   A 1 82  ? -19.52352 2.12133   21.89945  1.000 24.09056 ?  62  THR   A C   1 
ATOM   484  O O   . THR   A 1 82  ? -20.71156 2.29063   21.59815  1.000 25.89436 ?  62  THR   A O   1 
ATOM   485  C CB  . THR   A 1 82  ? -17.73677 3.41263   20.70407  1.000 19.76747 ?  62  THR   A CB  1 
ATOM   486  O OG1 . THR   A 1 82  ? -16.81688 4.50553   20.81609  1.000 17.81496 ?  62  THR   A OG1 1 
ATOM   487  C CG2 . THR   A 1 82  ? -18.63756 3.63569   19.49711  1.000 21.24867 ?  62  THR   A CG2 1 
ATOM   488  N N   . ARG   A 1 83  ? -19.01895 0.91275   22.16088  1.000 17.62845 ?  63  ARG   A N   1 
ATOM   489  C CA  . ARG   A 1 83  ? -19.88451 -0.26054  22.22786  1.000 21.20636 ?  63  ARG   A CA  1 
ATOM   490  C C   . ARG   A 1 83  ? -20.92343 -0.10808  23.33095  1.000 21.93700 ?  63  ARG   A C   1 
ATOM   491  O O   . ARG   A 1 83  ? -22.10604 -0.41162  23.13441  1.000 25.80859 ?  63  ARG   A O   1 
ATOM   492  C CB  . ARG   A 1 83  ? -19.04384 -1.51656  22.45368  1.000 20.04476 ?  63  ARG   A CB  1 
ATOM   493  C CG  . ARG   A 1 83  ? -18.52342 -2.16344  21.18288  1.000 28.97258 ?  63  ARG   A CG  1 
ATOM   494  C CD  . ARG   A 1 83  ? -18.66637 -3.67354  21.26495  1.000 33.99113 ?  63  ARG   A CD  1 
ATOM   495  N NE  . ARG   A 1 83  ? -17.85189 -4.22582  22.34044  1.000 26.89004 ?  63  ARG   A NE  1 
ATOM   496  C CZ  . ARG   A 1 83  ? -18.06672 -5.39865  22.92071  1.000 35.61878 ?  63  ARG   A CZ  1 
ATOM   497  N NH1 . ARG   A 1 83  ? -19.06862 -6.17971  22.55184  1.000 36.19873 ?  63  ARG   A NH1 1 
ATOM   498  N NH2 . ARG   A 1 83  ? -17.25616 -5.79729  23.89702  1.000 26.31989 ?  63  ARG   A NH2 1 
ATOM   499  N N   . LEU   A 1 84  ? -20.49446 0.36617   24.50423  1.000 19.45821 ?  64  LEU   A N   1 
ATOM   500  C CA  . LEU   A 1 84  ? -21.42636 0.58872   25.60460  1.000 27.87134 ?  64  LEU   A CA  1 
ATOM   501  C C   . LEU   A 1 84  ? -22.50021 1.60101   25.23048  1.000 22.52992 ?  64  LEU   A C   1 
ATOM   502  O O   . LEU   A 1 84  ? -23.62702 1.52724   25.73478  1.000 26.12748 ?  64  LEU   A O   1 
ATOM   503  C CB  . LEU   A 1 84  ? -20.66695 1.05604   26.84650  1.000 23.50997 ?  64  LEU   A CB  1 
ATOM   504  C CG  . LEU   A 1 84  ? -20.31664 -0.00313  27.89205  1.000 33.64273 ?  64  LEU   A CG  1 
ATOM   505  C CD1 . LEU   A 1 84  ? -19.29814 0.55120   28.87489  1.000 32.60082 ?  64  LEU   A CD1 1 
ATOM   506  C CD2 . LEU   A 1 84  ? -21.56292 -0.48163  28.62140  1.000 29.64279 ?  64  LEU   A CD2 1 
ATOM   507  N N   . ALA   A 1 85  ? -22.17426 2.54646   24.34572  1.000 23.10032 ?  65  ALA   A N   1 
ATOM   508  C CA  . ALA   A 1 85  ? -23.15283 3.53238   23.90607  1.000 19.72954 ?  65  ALA   A CA  1 
ATOM   509  C C   . ALA   A 1 85  ? -24.25309 2.91862   23.05026  1.000 26.67876 ?  65  ALA   A C   1 
ATOM   510  O O   . ALA   A 1 85  ? -25.31840 3.52760   22.90332  1.000 25.42227 ?  65  ALA   A O   1 
ATOM   511  C CB  . ALA   A 1 85  ? -22.45493 4.65513   23.13886  1.000 23.23014 ?  65  ALA   A CB  1 
ATOM   512  N N   . THR   A 1 86  ? -24.02126 1.73678   22.47972  1.000 22.68341 ?  66  THR   A N   1 
ATOM   513  C CA  . THR   A 1 86  ? -25.05747 1.03660   21.73389  1.000 23.97083 ?  66  THR   A CA  1 
ATOM   514  C C   . THR   A 1 86  ? -25.91660 0.14289   22.61864  1.000 29.80793 ?  66  THR   A C   1 
ATOM   515  O O   . THR   A 1 86  ? -27.00776 -0.25947  22.19835  1.000 28.82197 ?  66  THR   A O   1 
ATOM   516  C CB  . THR   A 1 86  ? -24.43194 0.19495   20.61460  1.000 24.36915 ?  66  THR   A CB  1 
ATOM   517  O OG1 . THR   A 1 86  ? -23.59832 -0.82236  21.18314  1.000 23.53370 ?  66  THR   A OG1 1 
ATOM   518  C CG2 . THR   A 1 86  ? -23.58913 1.07111   19.69544  1.000 22.12244 ?  66  THR   A CG2 1 
ATOM   519  N N   . ASP   A 1 87  ? -25.45421 -0.17156  23.82710  1.000 26.88038 ?  67  ASP   A N   1 
ATOM   520  C CA  . ASP   A 1 87  ? -26.20246 -1.01508  24.75270  1.000 24.91482 ?  67  ASP   A CA  1 
ATOM   521  C C   . ASP   A 1 87  ? -27.29419 -0.16332  25.38796  1.000 30.95516 ?  67  ASP   A C   1 
ATOM   522  O O   . ASP   A 1 87  ? -27.00189 0.76306   26.15056  1.000 29.05949 ?  67  ASP   A O   1 
ATOM   523  C CB  . ASP   A 1 87  ? -25.26283 -1.60378  25.80324  1.000 27.05650 ?  67  ASP   A CB  1 
ATOM   524  C CG  . ASP   A 1 87  ? -25.93846 -2.63386  26.70313  1.000 27.20426 ?  67  ASP   A CG  1 
ATOM   525  O OD1 . ASP   A 1 87  ? -27.17786 -2.60871  26.85439  1.000 30.60379 ?  67  ASP   A OD1 1 
ATOM   526  O OD2 . ASP   A 1 87  ? -25.21209 -3.47121  27.27797  1.000 29.13812 ?  67  ASP   A OD2 1 
ATOM   527  N N   . GLU   A 1 88  ? -28.55367 -0.46975  25.07312  1.000 28.06871 ?  68  GLU   A N   1 
ATOM   528  C CA  . GLU   A 1 88  ? -29.67042 0.31885   25.57756  1.000 30.09325 ?  68  GLU   A CA  1 
ATOM   529  C C   . GLU   A 1 88  ? -30.06357 -0.04100  27.00421  1.000 33.03577 ?  68  GLU   A C   1 
ATOM   530  O O   . GLU   A 1 88  ? -30.92019 0.63813   27.57959  1.000 30.10375 ?  68  GLU   A O   1 
ATOM   531  C CB  . GLU   A 1 88  ? -30.88172 0.16655   24.65461  1.000 30.89143 ?  68  GLU   A CB  1 
ATOM   532  C CG  . GLU   A 1 88  ? -30.63980 0.67787   23.24297  1.000 39.25446 ?  68  GLU   A CG  1 
ATOM   533  C CD  . GLU   A 1 88  ? -31.88349 1.26840   22.61264  1.000 48.01857 ?  68  GLU   A CD  1 
ATOM   534  O OE1 . GLU   A 1 88  ? -32.93193 1.30978   23.29015  1.000 52.96706 ?  68  GLU   A OE1 1 
ATOM   535  O OE2 . GLU   A 1 88  ? -31.81053 1.69451   21.44032  1.000 51.43550 ?  68  GLU   A OE2 1 
ATOM   536  N N   . SER   A 1 89  ? -29.47021 -1.08378  27.58858  1.000 30.42294 ?  69  SER   A N   1 
ATOM   537  C CA  . SER   A 1 89  ? -29.71238 -1.37430  28.99609  1.000 31.13441 ?  69  SER   A CA  1 
ATOM   538  C C   . SER   A 1 89  ? -29.02233 -0.38184  29.92082  1.000 32.54125 ?  69  SER   A C   1 
ATOM   539  O O   . SER   A 1 89  ? -29.30731 -0.37931  31.12320  1.000 35.22294 ?  69  SER   A O   1 
ATOM   540  C CB  . SER   A 1 89  ? -29.25545 -2.79577  29.33032  1.000 34.43479 ?  69  SER   A CB  1 
ATOM   541  O OG  . SER   A 1 89  ? -27.85116 -2.92694  29.19246  1.000 27.86436 ?  69  SER   A OG  1 
ATOM   542  N N   . VAL   A 1 90  ? -28.13012 0.45197   29.39327  1.000 29.78571 ?  70  VAL   A N   1 
ATOM   543  C CA  . VAL   A 1 90  ? -27.41837 1.46112   30.16751  1.000 22.76299 ?  70  VAL   A CA  1 
ATOM   544  C C   . VAL   A 1 90  ? -27.87440 2.82644   29.67437  1.000 27.62852 ?  70  VAL   A C   1 
ATOM   545  O O   . VAL   A 1 90  ? -27.75181 3.13326   28.48161  1.000 29.47327 ?  70  VAL   A O   1 
ATOM   546  C CB  . VAL   A 1 90  ? -25.89476 1.30723   30.03934  1.000 31.99684 ?  70  VAL   A CB  1 
ATOM   547  C CG1 . VAL   A 1 90  ? -25.18007 2.35776   30.87457  1.000 32.73287 ?  70  VAL   A CG1 1 
ATOM   548  C CG2 . VAL   A 1 90  ? -25.46757 -0.09557  30.45128  1.000 33.49575 ?  70  VAL   A CG2 1 
ATOM   549  N N   . SER   A 1 91  ? -28.40006 3.64029   30.58647  1.000 23.08850 ?  71  SER   A N   1 
ATOM   550  C CA  . SER   A 1 91  ? -28.94371 4.93728   30.21550  1.000 29.03731 ?  71  SER   A CA  1 
ATOM   551  C C   . SER   A 1 91  ? -27.83947 5.87515   29.73169  1.000 26.42261 ?  71  SER   A C   1 
ATOM   552  O O   . SER   A 1 91  ? -26.65344 5.68852   30.01880  1.000 25.80496 ?  71  SER   A O   1 
ATOM   553  C CB  . SER   A 1 91  ? -29.68515 5.56541   31.39650  1.000 28.10730 ?  71  SER   A CB  1 
ATOM   554  O OG  . SER   A 1 91  ? -28.77891 6.01971   32.38702  1.000 24.99074 ?  71  SER   A OG  1 
ATOM   555  N N   . VAL   A 1 92  ? -28.25301 6.90022   28.98077  1.000 25.29794 ?  72  VAL   A N   1 
ATOM   556  C CA  . VAL   A 1 92  ? -27.30233 7.87923   28.45866  1.000 25.48612 ?  72  VAL   A CA  1 
ATOM   557  C C   . VAL   A 1 92  ? -26.63327 8.63350   29.59912  1.000 27.23932 ?  72  VAL   A C   1 
ATOM   558  O O   . VAL   A 1 92  ? -25.42996 8.91908   29.55357  1.000 30.53375 ?  72  VAL   A O   1 
ATOM   559  C CB  . VAL   A 1 92  ? -28.00601 8.84125   27.48370  1.000 27.71899 ?  72  VAL   A CB  1 
ATOM   560  C CG1 . VAL   A 1 92  ? -27.00237 9.81075   26.87359  1.000 27.92735 ?  72  VAL   A CG1 1 
ATOM   561  C CG2 . VAL   A 1 92  ? -28.73554 8.06247   26.40120  1.000 27.81747 ?  72  VAL   A CG2 1 
ATOM   562  N N   . GLU   A 1 93  ? -27.40224 8.97498   30.63654  1.000 28.39723 ?  73  GLU   A N   1 
ATOM   563  C CA  . GLU   A 1 93  ? -26.82046 9.64089   31.79704  1.000 30.71775 ?  73  GLU   A CA  1 
ATOM   564  C C   . GLU   A 1 93  ? -25.78844 8.75155   32.47742  1.000 27.36153 ?  73  GLU   A C   1 
ATOM   565  O O   . GLU   A 1 93  ? -24.76675 9.24009   32.97320  1.000 26.12118 ?  73  GLU   A O   1 
ATOM   566  C CB  . GLU   A 1 93  ? -27.91789 10.03727  32.78436  1.000 31.92623 ?  73  GLU   A CB  1 
ATOM   567  C CG  . GLU   A 1 93  ? -29.20440 10.51664  32.13410  1.000 38.68490 ?  73  GLU   A CG  1 
ATOM   568  C CD  . GLU   A 1 93  ? -29.03875 11.84152  31.41678  1.000 52.64045 ?  73  GLU   A CD  1 
ATOM   569  O OE1 . GLU   A 1 93  ? -28.33904 12.72615  31.95453  1.000 53.62362 ?  73  GLU   A OE1 1 
ATOM   570  O OE2 . GLU   A 1 93  ? -29.60587 11.99877  30.31518  1.000 50.46658 ?  73  GLU   A OE2 1 
ATOM   571  N N   . ASN   A 1 94  ? -26.03809 7.44055   32.51059  1.000 26.01261 ?  74  ASN   A N   1 
ATOM   572  C CA  . ASN   A 1 94  ? -25.06485 6.51982   33.08725  1.000 28.07962 ?  74  ASN   A CA  1 
ATOM   573  C C   . ASN   A 1 94  ? -23.81374 6.42793   32.22268  1.000 27.80303 ?  74  ASN   A C   1 
ATOM   574  O O   . ASN   A 1 94  ? -22.69576 6.37842   32.74741  1.000 24.28844 ?  74  ASN   A O   1 
ATOM   575  C CB  . ASN   A 1 94  ? -25.69486 5.14055   33.27708  1.000 25.36919 ?  74  ASN   A CB  1 
ATOM   576  C CG  . ASN   A 1 94  ? -26.43983 5.01668   34.59288  1.000 28.51217 ?  74  ASN   A CG  1 
ATOM   577  O OD1 . ASN   A 1 94  ? -26.93841 3.94466   34.93811  1.000 30.95774 ?  74  ASN   A OD1 1 
ATOM   578  N ND2 . ASN   A 1 94  ? -26.51512 6.11373   35.33687  1.000 23.26455 ?  74  ASN   A ND2 1 
ATOM   579  N N   . LEU   A 1 95  ? -23.98048 6.40305   30.89745  1.000 25.96241 ?  75  LEU   A N   1 
ATOM   580  C CA  . LEU   A 1 95  ? -22.82589 6.40431   30.00370  1.000 23.66215 ?  75  LEU   A CA  1 
ATOM   581  C C   . LEU   A 1 95  ? -21.93955 7.61397   30.25795  1.000 24.34353 ?  75  LEU   A C   1 
ATOM   582  O O   . LEU   A 1 95  ? -20.71314 7.49230   30.36164  1.000 22.07981 ?  75  LEU   A O   1 
ATOM   583  C CB  . LEU   A 1 95  ? -23.28522 6.38480   28.54671  1.000 25.52533 ?  75  LEU   A CB  1 
ATOM   584  C CG  . LEU   A 1 95  ? -23.65811 5.02244   27.96882  1.000 36.03367 ?  75  LEU   A CG  1 
ATOM   585  C CD1 . LEU   A 1 95  ? -24.76458 5.15635   26.93403  1.000 34.35777 ?  75  LEU   A CD1 1 
ATOM   586  C CD2 . LEU   A 1 95  ? -22.42610 4.36626   27.37510  1.000 40.51170 ?  75  LEU   A CD2 1 
ATOM   587  N N   . LEU   A 1 96  ? -22.54957 8.79665   30.35028  1.000 24.70066 ?  76  LEU   A N   1 
ATOM   588  C CA  . LEU   A 1 96  ? -21.78466 10.00508  30.63066  1.000 24.73095 ?  76  LEU   A CA  1 
ATOM   589  C C   . LEU   A 1 96  ? -21.11171 9.92010   31.99331  1.000 23.37482 ?  76  LEU   A C   1 
ATOM   590  O O   . LEU   A 1 96  ? -19.98441 10.39620  32.16840  1.000 22.25123 ?  76  LEU   A O   1 
ATOM   591  C CB  . LEU   A 1 96  ? -22.69751 11.22708  30.55441  1.000 22.96136 ?  76  LEU   A CB  1 
ATOM   592  C CG  . LEU   A 1 96  ? -23.07160 11.67941  29.14256  1.000 31.01296 ?  76  LEU   A CG  1 
ATOM   593  C CD1 . LEU   A 1 96  ? -23.95121 12.91498  29.19688  1.000 28.52807 ?  76  LEU   A CD1 1 
ATOM   594  C CD2 . LEU   A 1 96  ? -21.82393 11.94045  28.31251  1.000 26.20784 ?  76  LEU   A CD2 1 
ATOM   595  N N   . THR   A 1 97  ? -21.78588 9.30781   32.96996  1.000 19.24356 ?  77  THR   A N   1 
ATOM   596  C CA  . THR   A 1 97  ? -21.17282 9.11217   34.27923  1.000 23.81866 ?  77  THR   A CA  1 
ATOM   597  C C   . THR   A 1 97  ? -19.96281 8.19027   34.18345  1.000 21.09750 ?  77  THR   A C   1 
ATOM   598  O O   . THR   A 1 97  ? -18.92346 8.45060   34.80178  1.000 27.07762 ?  77  THR   A O   1 
ATOM   599  C CB  . THR   A 1 97  ? -22.20417 8.55544   35.26312  1.000 23.80811 ?  77  THR   A CB  1 
ATOM   600  O OG1 . THR   A 1 97  ? -23.16440 9.57214   35.57636  1.000 28.73467 ?  77  THR   A OG1 1 
ATOM   601  C CG2 . THR   A 1 97  ? -21.53105 8.09656   36.54704  1.000 26.41121 ?  77  THR   A CG2 1 
ATOM   602  N N   . VAL   A 1 98  ? -20.07364 7.11644   33.39711  1.000 23.74961 ?  78  VAL   A N   1 
ATOM   603  C CA  . VAL   A 1 98  ? -18.94753 6.20327   33.21381  1.000 27.14651 ?  78  VAL   A CA  1 
ATOM   604  C C   . VAL   A 1 98  ? -17.80113 6.90952   32.50007  1.000 23.67354 ?  78  VAL   A C   1 
ATOM   605  O O   . VAL   A 1 98  ? -16.63110 6.76968   32.87653  1.000 26.01998 ?  78  VAL   A O   1 
ATOM   606  C CB  . VAL   A 1 98  ? -19.39557 4.94212   32.45262  1.000 23.08939 ?  78  VAL   A CB  1 
ATOM   607  C CG1 . VAL   A 1 98  ? -18.20733 4.03687   32.18312  1.000 25.81111 ?  78  VAL   A CG1 1 
ATOM   608  C CG2 . VAL   A 1 98  ? -20.45147 4.19496   33.24501  1.000 24.19073 ?  78  VAL   A CG2 1 
ATOM   609  N N   . PHE   A 1 99  ? -18.11974 7.68056   31.45747  1.000 24.60707 ?  79  PHE   A N   1 
ATOM   610  C CA  . PHE   A 1 99  ? -17.07750 8.38146   30.71329  1.000 27.07405 ?  79  PHE   A CA  1 
ATOM   611  C C   . PHE   A 1 99  ? -16.39519 9.43314   31.58130  1.000 20.17918 ?  79  PHE   A C   1 
ATOM   612  O O   . PHE   A 1 99  ? -15.16283 9.52691   31.60847  1.000 21.50623 ?  79  PHE   A O   1 
ATOM   613  C CB  . PHE   A 1 99  ? -17.66660 9.01544   29.44967  1.000 19.63349 ?  79  PHE   A CB  1 
ATOM   614  C CG  . PHE   A 1 99  ? -16.66218 9.78122   28.62942  1.000 22.82859 ?  79  PHE   A CG  1 
ATOM   615  C CD1 . PHE   A 1 99  ? -16.40050 11.11785  28.89141  1.000 22.84068 ?  79  PHE   A CD1 1 
ATOM   616  C CD2 . PHE   A 1 99  ? -15.96993 9.15877   27.60497  1.000 19.34320 ?  79  PHE   A CD2 1 
ATOM   617  C CE1 . PHE   A 1 99  ? -15.47310 11.81820  28.14547  1.000 23.92719 ?  79  PHE   A CE1 1 
ATOM   618  C CE2 . PHE   A 1 99  ? -15.04152 9.85523   26.85408  1.000 22.08043 ?  79  PHE   A CE2 1 
ATOM   619  C CZ  . PHE   A 1 99  ? -14.79259 11.18633  27.12513  1.000 22.39791 ?  79  PHE   A CZ  1 
ATOM   620  N N   . ARG   A 1 100 ? -17.18349 10.23351  32.30400  1.000 18.54054 ?  80  ARG   A N   1 
ATOM   621  C CA  . ARG   A 1 100 ? -16.61505 11.30723  33.11320  1.000 18.57103 ?  80  ARG   A CA  1 
ATOM   622  C C   . ARG   A 1 100 ? -15.70605 10.78807  34.21993  1.000 23.51301 ?  80  ARG   A C   1 
ATOM   623  O O   . ARG   A 1 100 ? -14.86283 11.54220  34.71829  1.000 24.09912 ?  80  ARG   A O   1 
ATOM   624  C CB  . ARG   A 1 100 ? -17.73307 12.15990  33.71607  1.000 20.65654 ?  80  ARG   A CB  1 
ATOM   625  C CG  . ARG   A 1 100 ? -18.38157 13.11301  32.72596  1.000 22.57817 ?  80  ARG   A CG  1 
ATOM   626  C CD  . ARG   A 1 100 ? -19.79327 13.47560  33.15343  1.000 28.95918 ?  80  ARG   A CD  1 
ATOM   627  N NE  . ARG   A 1 100 ? -20.47515 14.28209  32.14843  1.000 34.71546 ?  80  ARG   A NE  1 
ATOM   628  C CZ  . ARG   A 1 100 ? -21.79123 14.42034  32.06636  1.000 29.17995 ?  80  ARG   A CZ  1 
ATOM   629  N NH1 . ARG   A 1 100 ? -22.60406 13.81486  32.91653  1.000 33.63068 ?  80  ARG   A NH1 1 
ATOM   630  N NH2 . ARG   A 1 100 ? -22.30478 15.18449  31.10659  1.000 30.13911 ?  80  ARG   A NH2 1 
ATOM   631  N N   . THR   A 1 101 ? -15.85489 9.52424   34.61395  1.000 22.48460 ?  81  THR   A N   1 
ATOM   632  C CA  . THR   A 1 101 ? -15.00719 8.92980   35.63989  1.000 21.60340 ?  81  THR   A CA  1 
ATOM   633  C C   . THR   A 1 101 ? -13.74948 8.29778   35.05639  1.000 23.95983 ?  81  THR   A C   1 
ATOM   634  O O   . THR   A 1 101 ? -12.65933 8.44992   35.61836  1.000 23.18379 ?  81  THR   A O   1 
ATOM   635  C CB  . THR   A 1 101 ? -15.79274 7.87349   36.42443  1.000 24.40855 ?  81  THR   A CB  1 
ATOM   636  O OG1 . THR   A 1 101 ? -17.03855 8.42656   36.86676  1.000 30.55995 ?  81  THR   A OG1 1 
ATOM   637  C CG2 . THR   A 1 101 ? -14.99592 7.38829   37.62645  1.000 25.01971 ?  81  THR   A CG2 1 
ATOM   638  N N   . LEU   A 1 102 ? -13.88283 7.60231   33.92893  1.000 27.63079 ?  82  LEU   A N   1 
ATOM   639  C CA  . LEU   A 1 102 ? -12.80170 6.80240   33.36886  1.000 21.72106 ?  82  LEU   A CA  1 
ATOM   640  C C   . LEU   A 1 102 ? -11.87871 7.59617   32.45352  1.000 22.58646 ?  82  LEU   A C   1 
ATOM   641  O O   . LEU   A 1 102 ? -10.70225 7.24072   32.31438  1.000 22.20607 ?  82  LEU   A O   1 
ATOM   642  C CB  . LEU   A 1 102 ? -13.39397 5.61889   32.59860  1.000 25.04408 ?  82  LEU   A CB  1 
ATOM   643  C CG  . LEU   A 1 102 ? -12.45625 4.62309   31.92097  1.000 26.40745 ?  82  LEU   A CG  1 
ATOM   644  C CD1 . LEU   A 1 102 ? -11.47602 4.03750   32.92625  1.000 23.97080 ?  82  LEU   A CD1 1 
ATOM   645  C CD2 . LEU   A 1 102 ? -13.26949 3.53487   31.24507  1.000 27.67786 ?  82  LEU   A CD2 1 
ATOM   646  N N   . ASP   A 1 103 ? -12.37873 8.66108   31.83439  1.000 20.72818 ?  83  ASP   A N   1 
ATOM   647  C CA  . ASP   A 1 103 ? -11.63671 9.40663   30.82195  1.000 21.06246 ?  83  ASP   A CA  1 
ATOM   648  C C   . ASP   A 1 103 ? -10.53136 10.30733  31.37595  1.000 19.33050 ?  83  ASP   A C   1 
ATOM   649  O O   . ASP   A 1 103 ? -9.40832  10.26247  30.85702  1.000 18.73336 ?  83  ASP   A O   1 
ATOM   650  C CB  . ASP   A 1 103 ? -12.59798 10.25192  29.98213  1.000 19.92809 ?  83  ASP   A CB  1 
ATOM   651  C CG  . ASP   A 1 103 ? -11.88863 11.02145  28.88732  1.000 19.06802 ?  83  ASP   A CG  1 
ATOM   652  O OD1 . ASP   A 1 103 ? -11.66163 10.44229  27.80523  1.000 21.64041 ?  83  ASP   A OD1 1 
ATOM   653  O OD2 . ASP   A 1 103 ? -11.55567 12.20461  29.10987  1.000 21.72914 ?  83  ASP   A OD2 1 
ATOM   654  N N   . PRO   A 1 104 ? -10.79175 11.14323  32.39792  1.000 20.45911 ?  84  PRO   A N   1 
ATOM   655  C CA  . PRO   A 1 104 ? -9.82339  12.21091  32.72256  1.000 21.84768 ?  84  PRO   A CA  1 
ATOM   656  C C   . PRO   A 1 104 ? -8.41491  11.72914  33.02597  1.000 20.12027 ?  84  PRO   A C   1 
ATOM   657  O O   . PRO   A 1 104 ? -7.45234  12.35046  32.55951  1.000 20.43851 ?  84  PRO   A O   1 
ATOM   658  C CB  . PRO   A 1 104 ? -10.46032 12.88833  33.94410  1.000 21.50279 ?  84  PRO   A CB  1 
ATOM   659  C CG  . PRO   A 1 104 ? -11.90897 12.65181  33.76758  1.000 25.73191 ?  84  PRO   A CG  1 
ATOM   660  C CD  . PRO   A 1 104 ? -11.98133 11.24177  33.26398  1.000 20.34316 ?  84  PRO   A CD  1 
ATOM   661  N N   . ILE   A 1 105 ? -8.25878  10.64630  33.79340  1.000 21.90727 ?  85  ILE   A N   1 
ATOM   662  C CA  . ILE   A 1 105 ? -6.91851  10.19365  34.16305  1.000 23.01369 ?  85  ILE   A CA  1 
ATOM   663  C C   . ILE   A 1 105 ? -6.08753  9.88334   32.92422  1.000 20.18088 ?  85  ILE   A C   1 
ATOM   664  O O   . ILE   A 1 105 ? -4.85891  10.03068  32.93580  1.000 26.12899 ?  85  ILE   A O   1 
ATOM   665  C CB  . ILE   A 1 105 ? -7.00389  8.98149   35.11469  1.000 22.89747 ?  85  ILE   A CB  1 
ATOM   666  C CG1 . ILE   A 1 105 ? -5.61350  8.61084   35.64295  1.000 21.79533 ?  85  ILE   A CG1 1 
ATOM   667  C CG2 . ILE   A 1 105 ? -7.66468  7.79359   34.42825  1.000 21.38626 ?  85  ILE   A CG2 1 
ATOM   668  C CD1 . ILE   A 1 105 ? -4.88239  9.75978   36.30892  1.000 19.14476 ?  85  ILE   A CD1 1 
ATOM   669  N N   . TYR   A 1 106 ? -6.73766  9.47770   31.83331  1.000 25.16647 ?  86  TYR   A N   1 
ATOM   670  C CA  . TYR   A 1 106 ? -6.03387  9.22634   30.58071  1.000 17.57286 ?  86  TYR   A CA  1 
ATOM   671  C C   . TYR   A 1 106 ? -5.81850  10.51786  29.79916  1.000 18.84283 ?  86  TYR   A C   1 
ATOM   672  O O   . TYR   A 1 106 ? -4.68424  10.87381  29.46185  1.000 18.07006 ?  86  TYR   A O   1 
ATOM   673  C CB  . TYR   A 1 106 ? -6.82221  8.22780   29.73132  1.000 19.91603 ?  86  TYR   A CB  1 
ATOM   674  C CG  . TYR   A 1 106 ? -6.59083  6.77547   30.06907  1.000 15.81275 ?  86  TYR   A CG  1 
ATOM   675  C CD1 . TYR   A 1 106 ? -7.33451  6.14942   31.05825  1.000 17.24185 ?  86  TYR   A CD1 1 
ATOM   676  C CD2 . TYR   A 1 106 ? -5.64853  6.02236   29.38044  1.000 16.61138 ?  86  TYR   A CD2 1 
ATOM   677  C CE1 . TYR   A 1 106 ? -7.13529  4.82213   31.36694  1.000 16.20180 ?  86  TYR   A CE1 1 
ATOM   678  C CE2 . TYR   A 1 106 ? -5.44266  4.68898   29.68204  1.000 19.95536 ?  86  TYR   A CE2 1 
ATOM   679  C CZ  . TYR   A 1 106 ? -6.19070  4.09533   30.67700  1.000 17.90475 ?  86  TYR   A CZ  1 
ATOM   680  O OH  . TYR   A 1 106 ? -5.99798  2.76965   30.98664  1.000 19.64874 ?  86  TYR   A OH  1 
ATOM   681  N N   . SER   A 1 107 ? -6.90783  11.23380  29.50727  1.000 16.98890 ?  87  SER   A N   1 
ATOM   682  C CA  . SER   A 1 107 ? -6.83808  12.36414  28.58762  1.000 22.32522 ?  87  SER   A CA  1 
ATOM   683  C C   . SER   A 1 107 ? -6.04894  13.53124  29.16594  1.000 25.54559 ?  87  SER   A C   1 
ATOM   684  O O   . SER   A 1 107 ? -5.38027  14.25117  28.41577  1.000 21.71314 ?  87  SER   A O   1 
ATOM   685  C CB  . SER   A 1 107 ? -8.24761  12.81312  28.20819  1.000 17.96507 ?  87  SER   A CB  1 
ATOM   686  O OG  . SER   A 1 107 ? -8.99223  13.19065  29.35273  1.000 20.26838 ?  87  SER   A OG  1 
ATOM   687  N N   . THR   A 1 108 ? -6.11665  13.74324  30.48217  1.000 23.41110 ?  88  THR   A N   1 
ATOM   688  C CA  . THR   A 1 108 ? -5.33836  14.81616  31.09464  1.000 28.89580 ?  88  THR   A CA  1 
ATOM   689  C C   . THR   A 1 108 ? -3.84478  14.56340  30.93004  1.000 23.82225 ?  88  THR   A C   1 
ATOM   690  O O   . THR   A 1 108 ? -3.08305  15.47141  30.57488  1.000 25.72325 ?  88  THR   A O   1 
ATOM   691  C CB  . THR   A 1 108 ? -5.70355  14.95690  32.57374  1.000 23.16014 ?  88  THR   A CB  1 
ATOM   692  O OG1 . THR   A 1 108 ? -7.01915  15.51367  32.69114  1.000 27.30309 ?  88  THR   A OG1 1 
ATOM   693  C CG2 . THR   A 1 108 ? -4.71119  15.86155  33.28861  1.000 25.98149 ?  88  THR   A CG2 1 
ATOM   694  N N   . PHE   A 1 109 ? -3.40832  13.32561  31.17891  1.000 22.49279 ?  89  PHE   A N   1 
ATOM   695  C CA  . PHE   A 1 109 ? -2.00588  12.98313  30.96593  1.000 27.64806 ?  89  PHE   A CA  1 
ATOM   696  C C   . PHE   A 1 109 ? -1.62514  13.12120  29.49732  1.000 25.51945 ?  89  PHE   A C   1 
ATOM   697  O O   . PHE   A 1 109 ? -0.56345  13.66488  29.17164  1.000 20.91683 ?  89  PHE   A O   1 
ATOM   698  C CB  . PHE   A 1 109 ? -1.72820  11.56480  31.47201  1.000 20.07126 ?  89  PHE   A CB  1 
ATOM   699  C CG  . PHE   A 1 109 ? -0.31633  11.09310  31.23138  1.000 19.44736 ?  89  PHE   A CG  1 
ATOM   700  C CD1 . PHE   A 1 109 ? 0.03570   10.46859  30.04246  1.000 20.20734 ?  89  PHE   A CD1 1 
ATOM   701  C CD2 . PHE   A 1 109 ? 0.66114   11.28451  32.19317  1.000 22.36247 ?  89  PHE   A CD2 1 
ATOM   702  C CE1 . PHE   A 1 109 ? 1.33258   10.03912  29.82276  1.000 24.71859 ?  89  PHE   A CE1 1 
ATOM   703  C CE2 . PHE   A 1 109 ? 1.96057   10.85774  31.97911  1.000 24.11711 ?  89  PHE   A CE2 1 
ATOM   704  C CZ  . PHE   A 1 109 ? 2.29666   10.23491  30.79332  1.000 23.80520 ?  89  PHE   A CZ  1 
ATOM   705  N N   . LEU   A 1 110 ? -2.48142  12.63846  28.59521  1.000 22.90916 ?  90  LEU   A N   1 
ATOM   706  C CA  . LEU   A 1 110 ? -2.18219  12.73755  27.17104  1.000 24.87438 ?  90  LEU   A CA  1 
ATOM   707  C C   . LEU   A 1 110 ? -2.15815  14.18567  26.69907  1.000 25.12736 ?  90  LEU   A C   1 
ATOM   708  O O   . LEU   A 1 110 ? -1.40999  14.52072  25.77363  1.000 24.68965 ?  90  LEU   A O   1 
ATOM   709  C CB  . LEU   A 1 110 ? -3.19963  11.93048  26.36470  1.000 24.74442 ?  90  LEU   A CB  1 
ATOM   710  C CG  . LEU   A 1 110 ? -3.13946  10.41311  26.54652  1.000 22.04444 ?  90  LEU   A CG  1 
ATOM   711  C CD1 . LEU   A 1 110 ? -4.43714  9.77507   26.08927  1.000 19.96942 ?  90  LEU   A CD1 1 
ATOM   712  C CD2 . LEU   A 1 110 ? -1.95841  9.82955   25.78522  1.000 22.80859 ?  90  LEU   A CD2 1 
ATOM   713  N N   . GLY   A 1 111 ? -2.95550  15.05438  27.32365  1.000 24.06114 ?  91  GLY   A N   1 
ATOM   714  C CA  . GLY   A 1 111 ? -2.96943  16.45143  26.92250  1.000 22.28362 ?  91  GLY   A CA  1 
ATOM   715  C C   . GLY   A 1 111 ? -1.66898  17.16835  27.22656  1.000 26.36668 ?  91  GLY   A C   1 
ATOM   716  O O   . GLY   A 1 111 ? -1.22352  18.01922  26.45191  1.000 28.79954 ?  91  GLY   A O   1 
ATOM   717  N N   . TYR   A 1 112 ? -1.04737  16.84316  28.35482  1.000 27.95454 ?  92  TYR   A N   1 
ATOM   718  C CA  . TYR   A 1 112 ? 0.21743   17.44600  28.74601  1.000 30.03157 ?  92  TYR   A CA  1 
ATOM   719  C C   . TYR   A 1 112 ? 1.42450   16.65501  28.26172  1.000 29.54345 ?  92  TYR   A C   1 
ATOM   720  O O   . TYR   A 1 112 ? 2.55655   17.01223  28.60322  1.000 34.82666 ?  92  TYR   A O   1 
ATOM   721  C CB  . TYR   A 1 112 ? 0.28329   17.59143  30.27119  1.000 32.39428 ?  92  TYR   A CB  1 
ATOM   722  C CG  . TYR   A 1 112 ? -0.65973  18.62696  30.84270  1.000 38.06049 ?  92  TYR   A CG  1 
ATOM   723  C CD1 . TYR   A 1 112 ? -0.58916  19.95537  30.44465  1.000 41.26771 ?  92  TYR   A CD1 1 
ATOM   724  C CD2 . TYR   A 1 112 ? -1.61738  18.27553  31.78587  1.000 43.22439 ?  92  TYR   A CD2 1 
ATOM   725  C CE1 . TYR   A 1 112 ? -1.44730  20.90413  30.96763  1.000 49.48171 ?  92  TYR   A CE1 1 
ATOM   726  C CE2 . TYR   A 1 112 ? -2.47975  19.21687  32.31416  1.000 47.43366 ?  92  TYR   A CE2 1 
ATOM   727  C CZ  . TYR   A 1 112 ? -2.39022  20.52915  31.90165  1.000 58.02191 ?  92  TYR   A CZ  1 
ATOM   728  O OH  . TYR   A 1 112 ? -3.24711  21.46936  32.42584  1.000 45.12144 ?  92  TYR   A OH  1 
ATOM   729  N N   A ASN   A 1 113 ? 1.21575   15.60393  27.47085  0.492 25.43004 ?  93  ASN   A N   1 
ATOM   730  N N   B ASN   A 1 113 ? 1.21921   15.59542  27.48502  0.508 25.40164 ?  93  ASN   A N   1 
ATOM   731  C CA  A ASN   A 1 113 ? 2.28945   14.72797  27.01751  0.492 25.76702 ?  93  ASN   A CA  1 
ATOM   732  C CA  B ASN   A 1 113 ? 2.31180   14.75383  27.01434  0.508 25.75302 ?  93  ASN   A CA  1 
ATOM   733  C C   A ASN   A 1 113 ? 2.23409   14.52845  25.50776  0.492 26.20878 ?  93  ASN   A C   1 
ATOM   734  C C   B ASN   A 1 113 ? 2.21312   14.52502  25.51269  0.508 26.20231 ?  93  ASN   A C   1 
ATOM   735  O O   A ASN   A 1 113 ? 2.52650   13.44302  24.99683  0.492 29.54616 ?  93  ASN   A O   1 
ATOM   736  O O   B ASN   A 1 113 ? 2.45194   13.42001  25.01549  0.508 29.73272 ?  93  ASN   A O   1 
ATOM   737  C CB  A ASN   A 1 113 ? 2.23710   13.38257  27.73816  0.492 25.30844 ?  93  ASN   A CB  1 
ATOM   738  C CB  B ASN   A 1 113 ? 2.34271   13.42805  27.77092  0.508 25.10165 ?  93  ASN   A CB  1 
ATOM   739  C CG  A ASN   A 1 113 ? 3.61045   12.88597  28.14245  0.492 28.93645 ?  93  ASN   A CG  1 
ATOM   740  C CG  B ASN   A 1 113 ? 2.88320   13.57845  29.17977  0.508 27.32355 ?  93  ASN   A CG  1 
ATOM   741  O OD1 A ASN   A 1 113 ? 4.29306   13.51112  28.95346  0.492 29.27720 ?  93  ASN   A OD1 1 
ATOM   742  O OD1 B ASN   A 1 113 ? 4.07295   13.38143  29.42471  0.508 29.29332 ?  93  ASN   A OD1 1 
ATOM   743  N ND2 A ASN   A 1 113 ? 4.02415   11.75795  27.57681  0.492 22.34674 ?  93  ASN   A ND2 1 
ATOM   744  N ND2 B ASN   A 1 113 ? 2.00956   13.93640  30.11405  0.508 24.32143 ?  93  ASN   A ND2 1 
ATOM   745  N N   . GLY   A 1 114 ? 1.85583   15.57077  24.76735  1.000 24.76930 ?  94  GLY   A N   1 
ATOM   746  C CA  . GLY   A 1 114 ? 1.89883   15.54914  23.31684  1.000 33.25955 ?  94  GLY   A CA  1 
ATOM   747  C C   . GLY   A 1 114 ? 0.57205   15.65411  22.59795  1.000 30.32405 ?  94  GLY   A C   1 
ATOM   748  O O   . GLY   A 1 114 ? 0.57423   15.85934  21.37542  1.000 30.23805 ?  94  GLY   A O   1 
ATOM   749  N N   . PHE   A 1 115 ? -0.55521  15.52196  23.29267  1.000 29.04578 ?  95  PHE   A N   1 
ATOM   750  C CA  . PHE   A 1 115 ? -1.86899  15.47006  22.65204  1.000 27.74829 ?  95  PHE   A CA  1 
ATOM   751  C C   . PHE   A 1 115 ? -2.81340  16.48071  23.28965  1.000 25.85295 ?  95  PHE   A C   1 
ATOM   752  O O   . PHE   A 1 115 ? -3.78687  16.10457  23.95219  1.000 27.75837 ?  95  PHE   A O   1 
ATOM   753  C CB  . PHE   A 1 115 ? -2.45743  14.06139  22.73612  1.000 25.52949 ?  95  PHE   A CB  1 
ATOM   754  C CG  . PHE   A 1 115 ? -1.59377  13.00116  22.12736  1.000 24.23800 ?  95  PHE   A CG  1 
ATOM   755  C CD1 . PHE   A 1 115 ? -1.62051  12.78224  20.76283  1.000 31.61147 ?  95  PHE   A CD1 1 
ATOM   756  C CD2 . PHE   A 1 115 ? -0.77421  12.20732  22.91563  1.000 28.56282 ?  95  PHE   A CD2 1 
ATOM   757  C CE1 . PHE   A 1 115 ? -0.83762  11.80615  20.18709  1.000 25.59281 ?  95  PHE   A CE1 1 
ATOM   758  C CE2 . PHE   A 1 115 ? 0.01195   11.22347  22.34425  1.000 27.60044 ?  95  PHE   A CE2 1 
ATOM   759  C CZ  . PHE   A 1 115 ? -0.02105  11.02394  20.97743  1.000 26.61229 ?  95  PHE   A CZ  1 
ATOM   760  N N   . PRO   A 1 116 ? -2.56462  17.78040  23.09716  1.000 20.53846 ?  96  PRO   A N   1 
ATOM   761  C CA  . PRO   A 1 116 ? -3.50335  18.77150  23.64816  1.000 23.82091 ?  96  PRO   A CA  1 
ATOM   762  C C   . PRO   A 1 116 ? -4.85378  18.76013  22.95571  1.000 23.14658 ?  96  PRO   A C   1 
ATOM   763  O O   . PRO   A 1 116 ? -5.88315  18.96282  23.61256  1.000 26.24705 ?  96  PRO   A O   1 
ATOM   764  C CB  . PRO   A 1 116 ? -2.76401  20.09965  23.44008  1.000 27.52551 ?  96  PRO   A CB  1 
ATOM   765  C CG  . PRO   A 1 116 ? -1.88693  19.84478  22.26145  1.000 27.59402 ?  96  PRO   A CG  1 
ATOM   766  C CD  . PRO   A 1 116 ? -1.42469  18.42511  22.42220  1.000 26.63606 ?  96  PRO   A CD  1 
ATOM   767  N N   . VAL   A 1 117 ? -4.87866  18.53305  21.64024  1.000 18.35674 ?  97  VAL   A N   1 
ATOM   768  C CA  . VAL   A 1 117 ? -6.14500  18.47974  20.91573  1.000 21.24991 ?  97  VAL   A CA  1 
ATOM   769  C C   . VAL   A 1 117 ? -6.95812  17.26906  21.35695  1.000 20.30978 ?  97  VAL   A C   1 
ATOM   770  O O   . VAL   A 1 117 ? -8.18895  17.33547  21.46309  1.000 20.21061 ?  97  VAL   A O   1 
ATOM   771  C CB  . VAL   A 1 117 ? -5.88926  18.47658  19.39598  1.000 18.73156 ?  97  VAL   A CB  1 
ATOM   772  C CG1 . VAL   A 1 117 ? -7.16136  18.13554  18.62812  1.000 21.74104 ?  97  VAL   A CG1 1 
ATOM   773  C CG2 . VAL   A 1 117 ? -5.33572  19.82296  18.94789  1.000 19.61227 ?  97  VAL   A CG2 1 
ATOM   774  N N   . LEU   A 1 118 ? -6.28448  16.14855  21.62969  1.000 22.79093 ?  98  LEU   A N   1 
ATOM   775  C CA  . LEU   A 1 118 ? -6.96994  14.97376  22.15983  1.000 20.14836 ?  98  LEU   A CA  1 
ATOM   776  C C   . LEU   A 1 118 ? -7.67002  15.29688  23.47412  1.000 22.98731 ?  98  LEU   A C   1 
ATOM   777  O O   . LEU   A 1 118 ? -8.85254  14.98233  23.65592  1.000 24.07043 ?  98  LEU   A O   1 
ATOM   778  C CB  . LEU   A 1 118 ? -5.97009  13.82709  22.33653  1.000 22.79460 ?  98  LEU   A CB  1 
ATOM   779  C CG  . LEU   A 1 118 ? -6.43522  12.47024  22.87571  1.000 27.81304 ?  98  LEU   A CG  1 
ATOM   780  C CD1 . LEU   A 1 118 ? -5.55923  11.36650  22.31207  1.000 19.86178 ?  98  LEU   A CD1 1 
ATOM   781  C CD2 . LEU   A 1 118 ? -6.38844  12.43051  24.39778  1.000 19.34806 ?  98  LEU   A CD2 1 
ATOM   782  N N   . ALA   A 1 119 ? -6.94955  15.92645  24.40630  1.000 21.14310 ?  99  ALA   A N   1 
ATOM   783  C CA  . ALA   A 1 119 ? -7.54393  16.27650  25.69129  1.000 22.72598 ?  99  ALA   A CA  1 
ATOM   784  C C   . ALA   A 1 119 ? -8.66627  17.29081  25.53130  1.000 24.69525 ?  99  ALA   A C   1 
ATOM   785  O O   . ALA   A 1 119 ? -9.64330  17.25706  26.28822  1.000 23.08371 ?  99  ALA   A O   1 
ATOM   786  C CB  . ALA   A 1 119 ? -6.46922  16.81776  26.63622  1.000 20.03248 ?  99  ALA   A CB  1 
ATOM   787  N N   . GLU   A 1 120 ? -8.54451  18.19467  24.55557  1.000 26.31250 ?  100 GLU   A N   1 
ATOM   788  C CA  . GLU   A 1 120 ? -9.59618  19.17591  24.30696  1.000 21.66881 ?  100 GLU   A CA  1 
ATOM   789  C C   . GLU   A 1 120 ? -10.91836 18.49294  23.98462  1.000 23.97925 ?  100 GLU   A C   1 
ATOM   790  O O   . GLU   A 1 120 ? -11.94829 18.77573  24.60742  1.000 25.55586 ?  100 GLU   A O   1 
ATOM   791  C CB  . GLU   A 1 120 ? -9.18315  20.10334  23.16376  1.000 25.19410 ?  100 GLU   A CB  1 
ATOM   792  C CG  . GLU   A 1 120 ? -10.31915 20.94538  22.59985  1.000 30.04196 ?  100 GLU   A CG  1 
ATOM   793  C CD  . GLU   A 1 120 ? -9.87941  21.78862  21.41796  1.000 26.62017 ?  100 GLU   A CD  1 
ATOM   794  O OE1 . GLU   A 1 120 ? -8.70300  21.67665  21.01647  1.000 27.16333 ?  100 GLU   A OE1 1 
ATOM   795  O OE2 . GLU   A 1 120 ? -10.70616 22.55871  20.88710  1.000 25.53700 ?  100 GLU   A OE2 1 
ATOM   796  N N   . TYR   A 1 121 ? -10.90631 17.57950  23.01540  1.000 23.86022 ?  101 TYR   A N   1 
ATOM   797  C CA  . TYR   A 1 121 ? -12.13935 16.93603  22.58902  1.000 24.42359 ?  101 TYR   A CA  1 
ATOM   798  C C   . TYR   A 1 121 ? -12.58386 15.83595  23.53877  1.000 20.88344 ?  101 TYR   A C   1 
ATOM   799  O O   . TYR   A 1 121 ? -13.73093 15.38726  23.44750  1.000 21.90475 ?  101 TYR   A O   1 
ATOM   800  C CB  . TYR   A 1 121 ? -11.97583 16.39129  21.17055  1.000 21.53739 ?  101 TYR   A CB  1 
ATOM   801  C CG  . TYR   A 1 121 ? -12.18478 17.46699  20.13498  1.000 23.33759 ?  101 TYR   A CG  1 
ATOM   802  C CD1 . TYR   A 1 121 ? -13.44676 17.72009  19.61483  1.000 19.64763 ?  101 TYR   A CD1 1 
ATOM   803  C CD2 . TYR   A 1 121 ? -11.12938 18.26267  19.71322  1.000 21.03293 ?  101 TYR   A CD2 1 
ATOM   804  C CE1 . TYR   A 1 121 ? -13.64539 18.71601  18.68117  1.000 21.62827 ?  101 TYR   A CE1 1 
ATOM   805  C CE2 . TYR   A 1 121 ? -11.31794 19.26156  18.78142  1.000 20.20882 ?  101 TYR   A CE2 1 
ATOM   806  C CZ  . TYR   A 1 121 ? -12.57707 19.48348  18.26962  1.000 22.11811 ?  101 TYR   A CZ  1 
ATOM   807  O OH  . TYR   A 1 121 ? -12.76979 20.47870  17.34376  1.000 25.76889 ?  101 TYR   A OH  1 
ATOM   808  N N   . ALA   A 1 122 ? -11.71374 15.40152  24.45172  1.000 17.05220 ?  102 ALA   A N   1 
ATOM   809  C CA  . ALA   A 1 122 ? -12.13981 14.45713  25.47771  1.000 17.46341 ?  102 ALA   A CA  1 
ATOM   810  C C   . ALA   A 1 122 ? -13.09926 15.11943  26.45844  1.000 20.41204 ?  102 ALA   A C   1 
ATOM   811  O O   . ALA   A 1 122 ? -14.13136 14.54086  26.81873  1.000 24.42982 ?  102 ALA   A O   1 
ATOM   812  C CB  . ALA   A 1 122 ? -10.92469 13.88797  26.20609  1.000 19.94381 ?  102 ALA   A CB  1 
ATOM   813  N N   . GLN   A 1 123 ? -12.77092 16.33613  26.90548  1.000 19.99934 ?  103 GLN   A N   1 
ATOM   814  C CA  . GLN   A 1 123 ? -13.71062 17.10440  27.71700  1.000 28.52569 ?  103 GLN   A CA  1 
ATOM   815  C C   . GLN   A 1 123 ? -15.00719 17.35243  26.95990  1.000 27.08274 ?  103 GLN   A C   1 
ATOM   816  O O   . GLN   A 1 123 ? -16.09650 17.31490  27.54371  1.000 25.26434 ?  103 GLN   A O   1 
ATOM   817  C CB  . GLN   A 1 123 ? -13.09253 18.44053  28.12991  1.000 30.02187 ?  103 GLN   A CB  1 
ATOM   818  C CG  . GLN   A 1 123 ? -11.61195 18.40498  28.45108  1.000 36.10312 ?  103 GLN   A CG  1 
ATOM   819  C CD  . GLN   A 1 123 ? -11.10158 19.74541  28.94886  1.000 44.91489 ?  103 GLN   A CD  1 
ATOM   820  O OE1 . GLN   A 1 123 ? -11.87156 20.57396  29.43593  1.000 37.90273 ?  103 GLN   A OE1 1 
ATOM   821  N NE2 . GLN   A 1 123 ? -9.79814  19.96982  28.81591  1.000 43.21354 ?  103 GLN   A NE2 1 
ATOM   822  N N   . ARG   A 1 124 ? -14.90448 17.61128  25.65508  1.000 25.50047 ?  104 ARG   A N   1 
ATOM   823  C CA  . ARG   A 1 124 ? -16.08042 17.93704  24.85701  1.000 23.37893 ?  104 ARG   A CA  1 
ATOM   824  C C   . ARG   A 1 124 ? -16.98391 16.72323  24.67818  1.000 28.63858 ?  104 ARG   A C   1 
ATOM   825  O O   . ARG   A 1 124 ? -18.21253 16.85735  24.63782  1.000 28.42844 ?  104 ARG   A O   1 
ATOM   826  C CB  . ARG   A 1 124 ? -15.63591 18.49108  23.50493  1.000 22.34066 ?  104 ARG   A CB  1 
ATOM   827  C CG  . ARG   A 1 124 ? -16.73923 19.08221  22.65440  1.000 28.70215 ?  104 ARG   A CG  1 
ATOM   828  C CD  . ARG   A 1 124 ? -16.13510 19.97613  21.58513  1.000 22.54813 ?  104 ARG   A CD  1 
ATOM   829  N NE  . ARG   A 1 124 ? -17.03431 20.19990  20.46078  1.000 26.52448 ?  104 ARG   A NE  1 
ATOM   830  C CZ  . ARG   A 1 124 ? -16.74210 20.96409  19.41773  1.000 25.62013 ?  104 ARG   A CZ  1 
ATOM   831  N NH1 . ARG   A 1 124 ? -15.58603 21.60171  19.33169  1.000 21.16953 ?  104 ARG   A NH1 1 
ATOM   832  N NH2 . ARG   A 1 124 ? -17.63238 21.09441  18.43847  1.000 26.35868 ?  104 ARG   A NH2 1 
ATOM   833  N N   . VAL   A 1 125 ? -16.39448 15.53094  24.56579  1.000 26.17894 ?  105 VAL   A N   1 
ATOM   834  C CA  . VAL   A 1 125 ? -17.19382 14.31580  24.43397  1.000 23.76147 ?  105 VAL   A CA  1 
ATOM   835  C C   . VAL   A 1 125 ? -18.00878 14.07833  25.69986  1.000 24.63885 ?  105 VAL   A C   1 
ATOM   836  O O   . VAL   A 1 125 ? -19.16500 13.63999  25.64159  1.000 25.32509 ?  105 VAL   A O   1 
ATOM   837  C CB  . VAL   A 1 125 ? -16.28454 13.11652  24.10142  1.000 20.85884 ?  105 VAL   A CB  1 
ATOM   838  C CG1 . VAL   A 1 125 ? -16.96852 11.80034  24.44317  1.000 28.35732 ?  105 VAL   A CG1 1 
ATOM   839  C CG2 . VAL   A 1 125 ? -15.88145 13.14677  22.63300  1.000 24.41281 ?  105 VAL   A CG2 1 
ATOM   840  N N   . GLY   A 1 126 ? -17.43133 14.38694  26.85941  1.000 23.97629 ?  106 GLY   A N   1 
ATOM   841  C CA  . GLY   A 1 126 ? -18.09965 14.21534  28.13224  1.000 27.66511 ?  106 GLY   A CA  1 
ATOM   842  C C   . GLY   A 1 126 ? -19.15038 15.24534  28.47398  1.000 31.44756 ?  106 GLY   A C   1 
ATOM   843  O O   . GLY   A 1 126 ? -19.71794 15.19143  29.56836  1.000 29.44283 ?  106 GLY   A O   1 
ATOM   844  N N   . GLN   A 1 127 ? -19.42821 16.18835  27.57698  1.000 29.85672 ?  107 GLN   A N   1 
ATOM   845  C CA  . GLN   A 1 127 ? -20.45838 17.18051  27.82683  1.000 29.57379 ?  107 GLN   A CA  1 
ATOM   846  C C   . GLN   A 1 127 ? -21.84013 16.53079  27.77163  1.000 28.18655 ?  107 GLN   A C   1 
ATOM   847  O O   . GLN   A 1 127 ? -21.99888 15.43817  27.22128  1.000 28.10800 ?  107 GLN   A O   1 
ATOM   848  C CB  . GLN   A 1 127 ? -20.35699 18.31347  26.80737  1.000 27.88530 ?  107 GLN   A CB  1 
ATOM   849  C CG  . GLN   A 1 127 ? -19.06098 19.10316  26.89003  1.000 22.81389 ?  107 GLN   A CG  1 
ATOM   850  C CD  . GLN   A 1 127 ? -19.09339 20.15218  27.98440  1.000 29.29365 ?  107 GLN   A CD  1 
ATOM   851  O OE1 . GLN   A 1 127 ? -20.16258 20.60424  28.39291  1.000 27.79173 ?  107 GLN   A OE1 1 
ATOM   852  N NE2 . GLN   A 1 127 ? -17.91847 20.54703  28.46385  1.000 32.79564 ?  107 GLN   A NE2 1 
ATOM   853  N N   . PRO   A 1 128 ? -22.85350 17.17357  28.35755  1.000 29.35550 ?  108 PRO   A N   1 
ATOM   854  C CA  . PRO   A 1 128 ? -24.20885 16.61280  28.29472  1.000 27.90439 ?  108 PRO   A CA  1 
ATOM   855  C C   . PRO   A 1 128 ? -24.66147 16.40241  26.85828  1.000 30.11002 ?  108 PRO   A C   1 
ATOM   856  O O   . PRO   A 1 128 ? -24.43125 17.23956  25.98286  1.000 29.92615 ?  108 PRO   A O   1 
ATOM   857  C CB  . PRO   A 1 128 ? -25.06365 17.66854  29.00427  1.000 33.36548 ?  108 PRO   A CB  1 
ATOM   858  C CG  . PRO   A 1 128 ? -24.12231 18.34269  29.93089  1.000 32.87390 ?  108 PRO   A CG  1 
ATOM   859  C CD  . PRO   A 1 128 ? -22.79474 18.36492  29.22448  1.000 33.33962 ?  108 PRO   A CD  1 
ATOM   860  N N   . ALA   A 1 129 ? -25.30637 15.26402  26.62514  1.000 29.90949 ?  109 ALA   A N   1 
ATOM   861  C CA  . ALA   A 1 129 ? -25.79190 14.88229  25.30914  1.000 30.63743 ?  109 ALA   A CA  1 
ATOM   862  C C   . ALA   A 1 129 ? -27.31282 14.92020  25.29191  1.000 32.38745 ?  109 ALA   A C   1 
ATOM   863  O O   . ALA   A 1 129 ? -27.96447 14.52946  26.26552  1.000 34.65562 ?  109 ALA   A O   1 
ATOM   864  C CB  . ALA   A 1 129 ? -25.29666 13.48584  24.92454  1.000 28.22078 ?  109 ALA   A CB  1 
ATOM   865  N N   . GLU   A 1 130 ? -27.87390 15.39604  24.17994  1.000 28.66499 ?  110 GLU   A N   1 
ATOM   866  C CA  . GLU   A 1 130 ? -29.32172 15.47608  24.04494  1.000 35.43102 ?  110 GLU   A CA  1 
ATOM   867  C C   . GLU   A 1 130 ? -29.95754 14.13215  23.71801  1.000 33.72261 ?  110 GLU   A C   1 
ATOM   868  O O   . GLU   A 1 130 ? -31.17351 13.98366  23.88226  1.000 32.71536 ?  110 GLU   A O   1 
ATOM   869  C CB  . GLU   A 1 130 ? -29.69534 16.49368  22.96436  1.000 43.80275 ?  110 GLU   A CB  1 
ATOM   870  C CG  . GLU   A 1 130 ? -29.48775 15.98949  21.54418  1.000 45.39305 ?  110 GLU   A CG  1 
ATOM   871  C CD  . GLU   A 1 130 ? -29.58796 17.09214  20.50867  1.000 56.56693 ?  110 GLU   A CD  1 
ATOM   872  O OE1 . GLU   A 1 130 ? -30.53718 17.90029  20.58753  1.000 61.20669 ?  110 GLU   A OE1 1 
ATOM   873  O OE2 . GLU   A 1 130 ? -28.71868 17.14875  19.61335  1.000 60.73053 ?  110 GLU   A OE2 1 
ATOM   874  N N   . SER   A 1 131 ? -29.17193 13.15697  23.26709  1.000 32.76868 ?  111 SER   A N   1 
ATOM   875  C CA  . SER   A 1 131 ? -29.70640 11.86063  22.87191  1.000 31.51497 ?  111 SER   A CA  1 
ATOM   876  C C   . SER   A 1 131 ? -28.56231 10.86267  22.78000  1.000 33.66301 ?  111 SER   A C   1 
ATOM   877  O O   . SER   A 1 131 ? -27.38927 11.24093  22.70788  1.000 29.03166 ?  111 SER   A O   1 
ATOM   878  C CB  . SER   A 1 131 ? -30.45135 11.94380  21.53496  1.000 32.25949 ?  111 SER   A CB  1 
ATOM   879  O OG  . SER   A 1 131 ? -29.55940 12.24207  20.47413  1.000 30.71817 ?  111 SER   A OG  1 
ATOM   880  N N   . ARG   A 1 132 ? -28.92568 9.57656   22.78252  1.000 26.30804 ?  112 ARG   A N   1 
ATOM   881  C CA  . ARG   A 1 132 ? -27.93504 8.52069   22.59949  1.000 27.67156 ?  112 ARG   A CA  1 
ATOM   882  C C   . ARG   A 1 132 ? -27.25481 8.62379   21.24122  1.000 23.06591 ?  112 ARG   A C   1 
ATOM   883  O O   . ARG   A 1 132 ? -26.07128 8.28892   21.11147  1.000 22.62188 ?  112 ARG   A O   1 
ATOM   884  C CB  . ARG   A 1 132 ? -28.59754 7.15057   22.75826  1.000 29.84579 ?  112 ARG   A CB  1 
ATOM   885  C CG  . ARG   A 1 132 ? -27.66592 5.96651   22.55456  1.000 27.72903 ?  112 ARG   A CG  1 
ATOM   886  C CD  . ARG   A 1 132 ? -28.42574 4.65070   22.64312  1.000 31.82365 ?  112 ARG   A CD  1 
ATOM   887  N NE  . ARG   A 1 132 ? -29.09848 4.48368   23.92607  1.000 29.32796 ?  112 ARG   A NE  1 
ATOM   888  C CZ  . ARG   A 1 132 ? -28.53222 3.95986   25.00422  1.000 32.82243 ?  112 ARG   A CZ  1 
ATOM   889  N NH1 . ARG   A 1 132 ? -27.28007 3.53349   24.98819  1.000 34.87571 ?  112 ARG   A NH1 1 
ATOM   890  N NH2 . ARG   A 1 132 ? -29.24003 3.86030   26.12590  1.000 30.69794 ?  112 ARG   A NH2 1 
ATOM   891  N N   . ALA   A 1 133 ? -27.98213 9.08797   20.22185  1.000 21.00584 ?  113 ALA   A N   1 
ATOM   892  C CA  . ALA   A 1 133 ? -27.39927 9.21350   18.89012  1.000 23.64622 ?  113 ALA   A CA  1 
ATOM   893  C C   . ALA   A 1 133 ? -26.30684 10.27516  18.85851  1.000 20.23770 ?  113 ALA   A C   1 
ATOM   894  O O   . ALA   A 1 133 ? -25.29844 10.11344  18.16144  1.000 22.18884 ?  113 ALA   A O   1 
ATOM   895  C CB  . ALA   A 1 133 ? -28.48952 9.53284   17.86815  1.000 21.05062 ?  113 ALA   A CB  1 
ATOM   896  N N   . GLU   A 1 134 ? -26.48853 11.37011  19.60095  1.000 25.32652 ?  114 GLU   A N   1 
ATOM   897  C CA  . GLU   A 1 134 ? -25.45342 12.39760  19.65393  1.000 26.75086 ?  114 GLU   A CA  1 
ATOM   898  C C   . GLU   A 1 134 ? -24.22355 11.90006  20.40242  1.000 26.58712 ?  114 GLU   A C   1 
ATOM   899  O O   . GLU   A 1 134 ? -23.08875 12.13762  19.97169  1.000 22.08478 ?  114 GLU   A O   1 
ATOM   900  C CB  . GLU   A 1 134 ? -26.00047 13.66822  20.30491  1.000 21.23897 ?  114 GLU   A CB  1 
ATOM   901  C CG  . GLU   A 1 134 ? -24.92223 14.65990  20.72024  1.000 33.01998 ?  114 GLU   A CG  1 
ATOM   902  C CD  . GLU   A 1 134 ? -25.47347 16.04587  20.98817  1.000 42.64272 ?  114 GLU   A CD  1 
ATOM   903  O OE1 . GLU   A 1 134 ? -26.22183 16.20924  21.97426  1.000 35.34561 ?  114 GLU   A OE1 1 
ATOM   904  O OE2 . GLU   A 1 134 ? -25.15397 16.97371  20.21469  1.000 51.57007 ?  114 GLU   A OE2 1 
ATOM   905  N N   . LEU   A 1 135 ? -24.42954 11.20549  21.52376  1.000 24.08970 ?  115 LEU   A N   1 
ATOM   906  C CA  . LEU   A 1 135 ? -23.30300 10.67821  22.28641  1.000 25.12725 ?  115 LEU   A CA  1 
ATOM   907  C C   . LEU   A 1 135 ? -22.55768 9.60626   21.50073  1.000 20.68058 ?  115 LEU   A C   1 
ATOM   908  O O   . LEU   A 1 135 ? -21.32155 9.56505   21.51563  1.000 22.09034 ?  115 LEU   A O   1 
ATOM   909  C CB  . LEU   A 1 135 ? -23.79236 10.12444  23.62374  1.000 22.78808 ?  115 LEU   A CB  1 
ATOM   910  C CG  . LEU   A 1 135 ? -22.72970 9.51873   24.54042  1.000 23.43703 ?  115 LEU   A CG  1 
ATOM   911  C CD1 . LEU   A 1 135 ? -21.60224 10.51093  24.78200  1.000 26.60546 ?  115 LEU   A CD1 1 
ATOM   912  C CD2 . LEU   A 1 135 ? -23.35150 9.07096   25.85391  1.000 32.54168 ?  115 LEU   A CD2 1 
ATOM   913  N N   . LEU   A 1 136 ? -23.29169 8.73011   20.80960  1.000 22.58857 ?  116 LEU   A N   1 
ATOM   914  C CA  . LEU   A 1 136 ? -22.64601 7.72640   19.97021  1.000 22.91369 ?  116 LEU   A CA  1 
ATOM   915  C C   . LEU   A 1 136 ? -21.86051 8.38012   18.84019  1.000 22.81442 ?  116 LEU   A C   1 
ATOM   916  O O   . LEU   A 1 136 ? -20.77819 7.90889   18.47332  1.000 22.40766 ?  116 LEU   A O   1 
ATOM   917  C CB  . LEU   A 1 136 ? -23.68968 6.75903   19.40975  1.000 22.25138 ?  116 LEU   A CB  1 
ATOM   918  C CG  . LEU   A 1 136 ? -23.17327 5.59609   18.55716  1.000 29.02566 ?  116 LEU   A CG  1 
ATOM   919  C CD1 . LEU   A 1 136 ? -22.31103 4.64396   19.38035  1.000 17.07454 ?  116 LEU   A CD1 1 
ATOM   920  C CD2 . LEU   A 1 136 ? -24.33264 4.85209   17.90909  1.000 30.12314 ?  116 LEU   A CD2 1 
ATOM   921  N N   . ASP   A 1 137 ? -22.38683 9.47286   18.27995  1.000 22.89045 ?  117 ASP   A N   1 
ATOM   922  C CA  . ASP   A 1 137 ? -21.69099 10.15777  17.19407  1.000 26.43320 ?  117 ASP   A CA  1 
ATOM   923  C C   . ASP   A 1 137 ? -20.39854 10.80092  17.68326  1.000 23.40737 ?  117 ASP   A C   1 
ATOM   924  O O   . ASP   A 1 137 ? -19.38164 10.77116  16.97995  1.000 22.37645 ?  117 ASP   A O   1 
ATOM   925  C CB  . ASP   A 1 137 ? -22.61126 11.20020  16.55714  1.000 26.02379 ?  117 ASP   A CB  1 
ATOM   926  C CG  . ASP   A 1 137 ? -22.03974 11.78069  15.27615  1.000 29.34534 ?  117 ASP   A CG  1 
ATOM   927  O OD1 . ASP   A 1 137 ? -21.27386 11.07136  14.59255  1.000 36.83310 ?  117 ASP   A OD1 1 
ATOM   928  O OD2 . ASP   A 1 137 ? -22.36203 12.94161  14.94829  1.000 34.58849 ?  117 ASP   A OD2 1 
ATOM   929  N N   . ARG   A 1 138 ? -20.41769 11.38692  18.88392  1.000 20.74872 ?  118 ARG   A N   1 
ATOM   930  C CA  . ARG   A 1 138 ? -19.18711 11.90477  19.47606  1.000 21.93958 ?  118 ARG   A CA  1 
ATOM   931  C C   . ARG   A 1 138 ? -18.17132 10.78947  19.68070  1.000 17.84840 ?  118 ARG   A C   1 
ATOM   932  O O   . ARG   A 1 138 ? -17.01696 10.89384  19.25012  1.000 20.94692 ?  118 ARG   A O   1 
ATOM   933  C CB  . ARG   A 1 138 ? -19.47957 12.58280  20.81502  1.000 20.94911 ?  118 ARG   A CB  1 
ATOM   934  C CG  . ARG   A 1 138 ? -20.42118 13.76907  20.77840  1.000 27.43659 ?  118 ARG   A CG  1 
ATOM   935  C CD  . ARG   A 1 138 ? -20.58142 14.31370  22.19113  1.000 25.15351 ?  118 ARG   A CD  1 
ATOM   936  N NE  . ARG   A 1 138 ? -21.66869 15.27511  22.31935  1.000 26.72795 ?  118 ARG   A NE  1 
ATOM   937  C CZ  . ARG   A 1 138 ? -22.17995 15.66945  23.47766  1.000 31.69874 ?  118 ARG   A CZ  1 
ATOM   938  N NH1 . ARG   A 1 138 ? -21.72920 15.19690  24.62839  1.000 32.58078 ?  118 ARG   A NH1 1 
ATOM   939  N NH2 . ARG   A 1 138 ? -23.16832 16.55920  23.48172  1.000 34.28593 ?  118 ARG   A NH2 1 
ATOM   940  N N   . LEU   A 1 139 ? -18.59129 9.70939   20.34436  1.000 20.33284 ?  119 LEU   A N   1 
ATOM   941  C CA  . LEU   A 1 139 ? -17.66468 8.63888   20.69592  1.000 20.88221 ?  119 LEU   A CA  1 
ATOM   942  C C   . LEU   A 1 139 ? -17.10610 7.95582   19.45463  1.000 20.16361 ?  119 LEU   A C   1 
ATOM   943  O O   . LEU   A 1 139 ? -15.91348 7.63791   19.39901  1.000 19.09633 ?  119 LEU   A O   1 
ATOM   944  C CB  . LEU   A 1 139 ? -18.36168 7.62355   21.60059  1.000 17.88537 ?  119 LEU   A CB  1 
ATOM   945  C CG  . LEU   A 1 139 ? -18.38450 7.96122   23.09328  1.000 18.66698 ?  119 LEU   A CG  1 
ATOM   946  C CD1 . LEU   A 1 139 ? -19.45126 7.15014   23.80949  1.000 15.08922 ?  119 LEU   A CD1 1 
ATOM   947  C CD2 . LEU   A 1 139 ? -17.01944 7.73554   23.72682  1.000 20.53427 ?  119 LEU   A CD2 1 
ATOM   948  N N   . THR   A 1 140 ? -17.95093 7.72606   18.44636  1.000 17.36195 ?  120 THR   A N   1 
ATOM   949  C CA  . THR   A 1 140 ? -17.48606 7.07374   17.22579  1.000 19.46376 ?  120 THR   A CA  1 
ATOM   950  C C   . THR   A 1 140 ? -16.46883 7.93638   16.48931  1.000 19.57038 ?  120 THR   A C   1 
ATOM   951  O O   . THR   A 1 140 ? -15.43514 7.43626   16.02972  1.000 18.46850 ?  120 THR   A O   1 
ATOM   952  C CB  . THR   A 1 140 ? -18.67440 6.75203   16.31911  1.000 21.07739 ?  120 THR   A CB  1 
ATOM   953  O OG1 . THR   A 1 140 ? -19.55959 5.84913   16.99394  1.000 31.94963 ?  120 THR   A OG1 1 
ATOM   954  C CG2 . THR   A 1 140 ? -18.20482 6.12086   15.02125  1.000 24.05859 ?  120 THR   A CG2 1 
ATOM   955  N N   . THR   A 1 141 ? -16.74304 9.23601   16.36874  1.000 17.69647 ?  121 THR   A N   1 
ATOM   956  C CA  . THR   A 1 141 ? -15.80384 10.13330  15.70442  1.000 17.69330 ?  121 THR   A CA  1 
ATOM   957  C C   . THR   A 1 141 ? -14.52213 10.28160  16.51653  1.000 19.35626 ?  121 THR   A C   1 
ATOM   958  O O   . THR   A 1 141 ? -13.41544 10.19912  15.97120  1.000 19.63288 ?  121 THR   A O   1 
ATOM   959  C CB  . THR   A 1 141 ? -16.46006 11.49533  15.47379  1.000 23.59443 ?  121 THR   A CB  1 
ATOM   960  O OG1 . THR   A 1 141 ? -17.50537 11.36317  14.50308  1.000 27.94068 ?  121 THR   A OG1 1 
ATOM   961  C CG2 . THR   A 1 141 ? -15.43914 12.50886  14.97557  1.000 17.55007 ?  121 THR   A CG2 1 
ATOM   962  N N   . PHE   A 1 142 ? -14.65461 10.49090  17.82848  1.000 18.35477 ?  122 PHE   A N   1 
ATOM   963  C CA  . PHE   A 1 142 ? -13.48076 10.66837  18.67779  1.000 20.06541 ?  122 PHE   A CA  1 
ATOM   964  C C   . PHE   A 1 142 ? -12.62713 9.40643   18.71189  1.000 17.78354 ?  122 PHE   A C   1 
ATOM   965  O O   . PHE   A 1 142 ? -11.39466 9.48485   18.76891  1.000 17.95476 ?  122 PHE   A O   1 
ATOM   966  C CB  . PHE   A 1 142 ? -13.92020 11.07142  20.08735  1.000 18.26104 ?  122 PHE   A CB  1 
ATOM   967  C CG  . PHE   A 1 142 ? -12.78517 11.43539  21.00563  1.000 18.99075 ?  122 PHE   A CG  1 
ATOM   968  C CD1 . PHE   A 1 142 ? -11.79126 12.30904  20.59535  1.000 16.97214 ?  122 PHE   A CD1 1 
ATOM   969  C CD2 . PHE   A 1 142 ? -12.72664 10.91859  22.29004  1.000 17.02574 ?  122 PHE   A CD2 1 
ATOM   970  C CE1 . PHE   A 1 142 ? -10.75137 12.64726  21.44443  1.000 16.15429 ?  122 PHE   A CE1 1 
ATOM   971  C CE2 . PHE   A 1 142 ? -11.69221 11.25368  23.14356  1.000 15.62665 ?  122 PHE   A CE2 1 
ATOM   972  C CZ  . PHE   A 1 142 ? -10.70271 12.11834  22.72032  1.000 18.43710 ?  122 PHE   A CZ  1 
ATOM   973  N N   . THR   A 1 143 ? -13.26350 8.23267   18.66279  1.000 19.24650 ?  123 THR   A N   1 
ATOM   974  C CA  . THR   A 1 143 ? -12.51057 6.98163   18.68592  1.000 17.88261 ?  123 THR   A CA  1 
ATOM   975  C C   . THR   A 1 143 ? -11.67779 6.81388   17.42082  1.000 17.21003 ?  123 THR   A C   1 
ATOM   976  O O   . THR   A 1 143 ? -10.51370 6.40035   17.48831  1.000 19.88530 ?  123 THR   A O   1 
ATOM   977  C CB  . THR   A 1 143 ? -13.46174 5.79597   18.86219  1.000 20.69064 ?  123 THR   A CB  1 
ATOM   978  O OG1 . THR   A 1 143 ? -14.04463 5.84008   20.17068  1.000 14.60139 ?  123 THR   A OG1 1 
ATOM   979  C CG2 . THR   A 1 143 ? -12.72102 4.47750   18.69200  1.000 19.04925 ?  123 THR   A CG2 1 
ATOM   980  N N   . GLU   A 1 144 ? -12.25437 7.13452   16.25907  1.000 15.83953 ?  124 GLU   A N   1 
ATOM   981  C CA  . GLU   A 1 144 ? -11.50994 7.02067   15.00914  1.000 17.62581 ?  124 GLU   A CA  1 
ATOM   982  C C   . GLU   A 1 144 ? -10.32917 7.98195   14.98262  1.000 12.67393 ?  124 GLU   A C   1 
ATOM   983  O O   . GLU   A 1 144 ? -9.25420  7.64332   14.47384  1.000 18.36176 ?  124 GLU   A O   1 
ATOM   984  C CB  . GLU   A 1 144 ? -12.43551 7.27618   13.81910  1.000 13.78697 ?  124 GLU   A CB  1 
ATOM   985  C CG  . GLU   A 1 144 ? -11.72603 7.24446   12.47517  1.000 17.98283 ?  124 GLU   A CG  1 
ATOM   986  C CD  . GLU   A 1 144 ? -12.68152 7.31425   11.29945  1.000 20.72430 ?  124 GLU   A CD  1 
ATOM   987  O OE1 . GLU   A 1 144 ? -13.90152 7.45796   11.52596  1.000 23.34056 ?  124 GLU   A OE1 1 
ATOM   988  O OE2 . GLU   A 1 144 ? -12.20973 7.22502   10.14631  1.000 18.71934 ?  124 GLU   A OE2 1 
ATOM   989  N N   . TYR   A 1 145 ? -10.51144 9.18754   15.52584  1.000 17.72618 ?  125 TYR   A N   1 
ATOM   990  C CA  . TYR   A 1 145 ? -9.41737  10.15108  15.57723  1.000 16.05135 ?  125 TYR   A CA  1 
ATOM   991  C C   . TYR   A 1 145 ? -8.28023  9.64801   16.45744  1.000 12.39787 ?  125 TYR   A C   1 
ATOM   992  O O   . TYR   A 1 145 ? -7.10551  9.74693   16.08272  1.000 15.70708 ?  125 TYR   A O   1 
ATOM   993  C CB  . TYR   A 1 145 ? -9.94189  11.50005  16.07377  1.000 17.25398 ?  125 TYR   A CB  1 
ATOM   994  C CG  . TYR   A 1 145 ? -8.87328  12.45631  16.55294  1.000 17.18553 ?  125 TYR   A CG  1 
ATOM   995  C CD1 . TYR   A 1 145 ? -8.04511  13.11276  15.65155  1.000 19.60264 ?  125 TYR   A CD1 1 
ATOM   996  C CD2 . TYR   A 1 145 ? -8.70110  12.71214  17.90680  1.000 18.13500 ?  125 TYR   A CD2 1 
ATOM   997  C CE1 . TYR   A 1 145 ? -7.07038  13.99086  16.08584  1.000 19.67312 ?  125 TYR   A CE1 1 
ATOM   998  C CE2 . TYR   A 1 145 ? -7.73018  13.58836  18.35049  1.000 17.26578 ?  125 TYR   A CE2 1 
ATOM   999  C CZ  . TYR   A 1 145 ? -6.91806  14.22490  17.43700  1.000 18.31923 ?  125 TYR   A CZ  1 
ATOM   1000 O OH  . TYR   A 1 145 ? -5.94975  15.09749  17.87706  1.000 25.22017 ?  125 TYR   A OH  1 
ATOM   1001 N N   . VAL   A 1 146 ? -8.60994  9.09429   17.62706  1.000 16.65870 ?  126 VAL   A N   1 
ATOM   1002 C CA  . VAL   A 1 146 ? -7.57712  8.56123   18.50963  1.000 16.84250 ?  126 VAL   A CA  1 
ATOM   1003 C C   . VAL   A 1 146 ? -6.96681  7.29682   17.91781  1.000 17.84056 ?  126 VAL   A C   1 
ATOM   1004 O O   . VAL   A 1 146 ? -5.77007  7.03281   18.09675  1.000 17.06733 ?  126 VAL   A O   1 
ATOM   1005 C CB  . VAL   A 1 146 ? -8.15631  8.31437   19.91682  1.000 18.73476 ?  126 VAL   A CB  1 
ATOM   1006 C CG1 . VAL   A 1 146 ? -7.11073  7.69011   20.83134  1.000 15.63251 ?  126 VAL   A CG1 1 
ATOM   1007 C CG2 . VAL   A 1 146 ? -8.67498  9.61566   20.51274  1.000 19.24829 ?  126 VAL   A CG2 1 
ATOM   1008 N N   . ASN   A 1 147 ? -7.76460  6.50368   17.19700  1.000 21.59560 ?  127 ASN   A N   1 
ATOM   1009 C CA  . ASN   A 1 147 ? -7.22720  5.31647   16.53948  1.000 17.21085 ?  127 ASN   A CA  1 
ATOM   1010 C C   . ASN   A 1 147 ? -6.14408  5.68482   15.53431  1.000 19.68132 ?  127 ASN   A C   1 
ATOM   1011 O O   . ASN   A 1 147 ? -5.14200  4.97269   15.40066  1.000 19.21047 ?  127 ASN   A O   1 
ATOM   1012 C CB  . ASN   A 1 147 ? -8.34920  4.54026   15.84934  1.000 14.95567 ?  127 ASN   A CB  1 
ATOM   1013 C CG  . ASN   A 1 147 ? -9.10061  3.62942   16.79840  1.000 18.57805 ?  127 ASN   A CG  1 
ATOM   1014 O OD1 . ASN   A 1 147 ? -8.59259  3.25769   17.85488  1.000 18.30420 ?  127 ASN   A OD1 1 
ATOM   1015 N ND2 . ASN   A 1 147 ? -10.32097 3.26382   16.42337  1.000 16.71243 ?  127 ASN   A ND2 1 
ATOM   1016 N N   . ARG   A 1 148 ? -6.32625  6.79754   14.81980  1.000 16.86554 ?  128 ARG   A N   1 
ATOM   1017 C CA  . ARG   A 1 148 ? -5.33782  7.20654   13.82795  1.000 22.48011 ?  128 ARG   A CA  1 
ATOM   1018 C C   . ARG   A 1 148 ? -4.06907  7.72606   14.49258  1.000 18.58901 ?  128 ARG   A C   1 
ATOM   1019 O O   . ARG   A 1 148 ? -2.96066  7.47223   14.00644  1.000 19.77639 ?  128 ARG   A O   1 
ATOM   1020 C CB  . ARG   A 1 148 ? -5.93488  8.26122   12.89767  1.000 17.26644 ?  128 ARG   A CB  1 
ATOM   1021 C CG  . ARG   A 1 148 ? -5.02494  8.66109   11.74897  1.000 17.24039 ?  128 ARG   A CG  1 
ATOM   1022 C CD  . ARG   A 1 148 ? -4.64548  7.45879   10.90110  1.000 20.39562 ?  128 ARG   A CD  1 
ATOM   1023 N NE  . ARG   A 1 148 ? -5.80904  6.82500   10.29189  1.000 19.73672 ?  128 ARG   A NE  1 
ATOM   1024 C CZ  . ARG   A 1 148 ? -5.81917  5.59076   9.80708   1.000 19.71143 ?  128 ARG   A CZ  1 
ATOM   1025 N NH1 . ARG   A 1 148 ? -4.73791  4.82935   9.83448   1.000 19.21088 ?  128 ARG   A NH1 1 
ATOM   1026 N NH2 . ARG   A 1 148 ? -6.94269  5.10745   9.28395   1.000 16.90255 ?  128 ARG   A NH2 1 
ATOM   1027 N N   . LEU   A 1 149 ? -4.20769  8.45877   15.60040  1.000 17.79377 ?  129 LEU   A N   1 
ATOM   1028 C CA  . LEU   A 1 149 ? -3.02876  8.85258   16.36502  1.000 17.57312 ?  129 LEU   A CA  1 
ATOM   1029 C C   . LEU   A 1 149 ? -2.27596  7.62797   16.87045  1.000 19.54945 ?  129 LEU   A C   1 
ATOM   1030 O O   . LEU   A 1 149 ? -1.03948  7.59684   16.85229  1.000 19.20015 ?  129 LEU   A O   1 
ATOM   1031 C CB  . LEU   A 1 149 ? -3.43144  9.75777   17.53041  1.000 18.40050 ?  129 LEU   A CB  1 
ATOM   1032 C CG  . LEU   A 1 149 ? -3.94614  11.16129  17.20043  1.000 19.04078 ?  129 LEU   A CG  1 
ATOM   1033 C CD1 . LEU   A 1 149 ? -4.54491  11.80240  18.44043  1.000 16.30773 ?  129 LEU   A CD1 1 
ATOM   1034 C CD2 . LEU   A 1 149 ? -2.83525  12.03385  16.63542  1.000 20.28251 ?  129 LEU   A CD2 1 
ATOM   1035 N N   . THR   A 1 150 ? -3.00819  6.60422   17.31795  1.000 19.35679 ?  130 THR   A N   1 
ATOM   1036 C CA  . THR   A 1 150 ? -2.36984  5.36156   17.74016  1.000 15.17276 ?  130 THR   A CA  1 
ATOM   1037 C C   . THR   A 1 150 ? -1.68164  4.67367   16.56694  1.000 18.31874 ?  130 THR   A C   1 
ATOM   1038 O O   . THR   A 1 150 ? -0.57361  4.14244   16.71184  1.000 17.91253 ?  130 THR   A O   1 
ATOM   1039 C CB  . THR   A 1 150 ? -3.40644  4.43247   18.38000  1.000 14.68461 ?  130 THR   A CB  1 
ATOM   1040 O OG1 . THR   A 1 150 ? -3.91941  5.03274   19.57645  1.000 16.70727 ?  130 THR   A OG1 1 
ATOM   1041 C CG2 . THR   A 1 150 ? -2.78969  3.08251   18.71975  1.000 13.25430 ?  130 THR   A CG2 1 
ATOM   1042 N N   . ALA   A 1 151 ? -2.32217  4.68329   15.39387  1.000 13.71645 ?  131 ALA   A N   1 
ATOM   1043 C CA  . ALA   A 1 151 ? -1.73131  4.08062   14.20225  1.000 16.53160 ?  131 ALA   A CA  1 
ATOM   1044 C C   . ALA   A 1 151 ? -0.36623  4.68159   13.89492  1.000 18.33250 ?  131 ALA   A C   1 
ATOM   1045 O O   . ALA   A 1 151 ? 0.61473   3.95917   13.68511  1.000 18.64260 ?  131 ALA   A O   1 
ATOM   1046 C CB  . ALA   A 1 151 ? -2.66988  4.26234   13.00900  1.000 15.95872 ?  131 ALA   A CB  1 
ATOM   1047 N N   . TRP   A 1 152 ? -0.28962  6.01236   13.85896  1.000 19.22279 ?  132 TRP   A N   1 
ATOM   1048 C CA  . TRP   A 1 152 ? 0.97287   6.67299   13.55047  1.000 19.46018 ?  132 TRP   A CA  1 
ATOM   1049 C C   . TRP   A 1 152 ? 1.97861   6.49844   14.68096  1.000 19.05534 ?  132 TRP   A C   1 
ATOM   1050 O O   . TRP   A 1 152 ? 3.17581   6.31766   14.42949  1.000 17.84087 ?  132 TRP   A O   1 
ATOM   1051 C CB  . TRP   A 1 152 ? 0.72541   8.15222   13.27005  1.000 17.71441 ?  132 TRP   A CB  1 
ATOM   1052 C CG  . TRP   A 1 152 ? 0.31447   8.42403   11.85996  1.000 22.72670 ?  132 TRP   A CG  1 
ATOM   1053 C CD1 . TRP   A 1 152 ? -0.95642  8.60532   11.39920  1.000 21.28776 ?  132 TRP   A CD1 1 
ATOM   1054 C CD2 . TRP   A 1 152 ? 1.17671   8.55705   10.72375  1.000 21.50937 ?  132 TRP   A CD2 1 
ATOM   1055 N NE1 . TRP   A 1 152 ? -0.93960  8.83768   10.04544  1.000 22.52604 ?  132 TRP   A NE1 1 
ATOM   1056 C CE2 . TRP   A 1 152 ? 0.35806   8.81403   9.60676   1.000 23.26887 ?  132 TRP   A CE2 1 
ATOM   1057 C CE3 . TRP   A 1 152 ? 2.56072   8.48248   10.54253  1.000 24.86695 ?  132 TRP   A CE3 1 
ATOM   1058 C CZ2 . TRP   A 1 152 ? 0.87684   8.99573   8.32683   1.000 25.91593 ?  132 TRP   A CZ2 1 
ATOM   1059 C CZ3 . TRP   A 1 152 ? 3.07457   8.66420   9.27054   1.000 24.76973 ?  132 TRP   A CZ3 1 
ATOM   1060 C CH2 . TRP   A 1 152 ? 2.23405   8.91699   8.17932   1.000 25.36782 ?  132 TRP   A CH2 1 
ATOM   1061 N N   . SER   A 1 153 ? 1.51214   6.54958   15.93232  1.000 14.40998 ?  133 SER   A N   1 
ATOM   1062 C CA  . SER   A 1 153 ? 2.40746   6.33180   17.06448  1.000 15.70856 ?  133 SER   A CA  1 
ATOM   1063 C C   . SER   A 1 153 ? 2.99119   4.92616   17.04349  1.000 22.48583 ?  133 SER   A C   1 
ATOM   1064 O O   . SER   A 1 153 ? 4.17340   4.73164   17.34934  1.000 22.33838 ?  133 SER   A O   1 
ATOM   1065 C CB  . SER   A 1 153 ? 1.66786   6.57866   18.37792  1.000 16.15736 ?  133 SER   A CB  1 
ATOM   1066 O OG  . SER   A 1 153 ? 2.54900   6.44981   19.47969  1.000 19.73034 ?  133 SER   A OG  1 
ATOM   1067 N N   . HIS   A 1 154 ? 2.17367   3.93155   16.69101  1.000 22.90853 ?  134 HIS   A N   1 
ATOM   1068 C CA  . HIS   A 1 154 ? 2.66701   2.56145   16.60672  1.000 18.79541 ?  134 HIS   A CA  1 
ATOM   1069 C C   . HIS   A 1 154 ? 3.68597   2.40823   15.48523  1.000 19.40573 ?  134 HIS   A C   1 
ATOM   1070 O O   . HIS   A 1 154 ? 4.65552   1.65139   15.61614  1.000 20.27557 ?  134 HIS   A O   1 
ATOM   1071 C CB  . HIS   A 1 154 ? 1.49826   1.59668   16.40721  1.000 20.60372 ?  134 HIS   A CB  1 
ATOM   1072 C CG  . HIS   A 1 154 ? 1.91587   0.21748   16.00228  1.000 20.59194 ?  134 HIS   A CG  1 
ATOM   1073 N ND1 . HIS   A 1 154 ? 2.20223   -0.77324  16.91653  1.000 20.71941 ?  134 HIS   A ND1 1 
ATOM   1074 C CD2 . HIS   A 1 154 ? 2.09099   -0.33729  14.77940  1.000 23.81315 ?  134 HIS   A CD2 1 
ATOM   1075 C CE1 . HIS   A 1 154 ? 2.54004   -1.87741  16.27462  1.000 22.56657 ?  134 HIS   A CE1 1 
ATOM   1076 N NE2 . HIS   A 1 154 ? 2.48041   -1.63972  14.97673  1.000 26.22499 ?  134 HIS   A NE2 1 
ATOM   1077 N N   . HIS   A 1 155 ? 3.48516   3.11955   14.37404  1.000 19.24654 ?  135 HIS   A N   1 
ATOM   1078 C CA  . HIS   A 1 155 ? 4.40760   3.00025   13.25032  1.000 20.75217 ?  135 HIS   A CA  1 
ATOM   1079 C C   . HIS   A 1 155 ? 5.78934   3.54014   13.59686  1.000 19.28755 ?  135 HIS   A C   1 
ATOM   1080 O O   . HIS   A 1 155 ? 6.80379   2.98252   13.16258  1.000 23.72731 ?  135 HIS   A O   1 
ATOM   1081 C CB  . HIS   A 1 155 ? 3.85090   3.72629   12.02716  1.000 19.00898 ?  135 HIS   A CB  1 
ATOM   1082 C CG  . HIS   A 1 155 ? 4.83470   3.84980   10.90751  1.000 18.83964 ?  135 HIS   A CG  1 
ATOM   1083 N ND1 . HIS   A 1 155 ? 5.16936   2.79089   10.09160  1.000 22.88920 ?  135 HIS   A ND1 1 
ATOM   1084 C CD2 . HIS   A 1 155 ? 5.57507   4.90102   10.48357  1.000 21.78371 ?  135 HIS   A CD2 1 
ATOM   1085 C CE1 . HIS   A 1 155 ? 6.06529   3.18752   9.20569   1.000 24.66850 ?  135 HIS   A CE1 1 
ATOM   1086 N NE2 . HIS   A 1 155 ? 6.32910   4.46357   9.42228   1.000 27.32031 ?  135 HIS   A NE2 1 
ATOM   1087 N N   . TYR   A 1 156 ? 5.85406   4.61934   14.37102  1.000 20.56370 ?  136 TYR   A N   1 
ATOM   1088 C CA  . TYR   A 1 156 ? 7.11381   5.30041   14.62853  1.000 22.04654 ?  136 TYR   A CA  1 
ATOM   1089 C C   . TYR   A 1 156 ? 7.75474   4.92947   15.95850  1.000 23.93132 ?  136 TYR   A C   1 
ATOM   1090 O O   . TYR   A 1 156 ? 8.86301   5.39558   16.24045  1.000 24.21445 ?  136 TYR   A O   1 
ATOM   1091 C CB  . TYR   A 1 156 ? 6.91592   6.81786   14.56159  1.000 19.73473 ?  136 TYR   A CB  1 
ATOM   1092 C CG  . TYR   A 1 156 ? 6.95932   7.37046   13.15696  1.000 24.15773 ?  136 TYR   A CG  1 
ATOM   1093 C CD1 . TYR   A 1 156 ? 8.13136   7.33513   12.41122  1.000 23.78304 ?  136 TYR   A CD1 1 
ATOM   1094 C CD2 . TYR   A 1 156 ? 5.82895   7.92387   12.57463  1.000 23.85019 ?  136 TYR   A CD2 1 
ATOM   1095 C CE1 . TYR   A 1 156 ? 8.17448   7.83922   11.12585  1.000 24.47292 ?  136 TYR   A CE1 1 
ATOM   1096 C CE2 . TYR   A 1 156 ? 5.86262   8.43007   11.29136  1.000 26.15539 ?  136 TYR   A CE2 1 
ATOM   1097 C CZ  . TYR   A 1 156 ? 7.03599   8.38476   10.57091  1.000 26.03155 ?  136 TYR   A CZ  1 
ATOM   1098 O OH  . TYR   A 1 156 ? 7.06794   8.88882   9.29154   1.000 32.33052 ?  136 TYR   A OH  1 
ATOM   1099 N N   . PHE   A 1 157 ? 7.11182   4.10718   16.77244  1.000 21.82148 ?  137 PHE   A N   1 
ATOM   1100 C CA  . PHE   A 1 157 ? 7.72580   3.71744   18.03382  1.000 22.04993 ?  137 PHE   A CA  1 
ATOM   1101 C C   . PHE   A 1 157 ? 8.90701   2.78874   17.77228  1.000 24.39159 ?  137 PHE   A C   1 
ATOM   1102 O O   . PHE   A 1 157 ? 8.78913   1.85193   16.97264  1.000 22.13240 ?  137 PHE   A O   1 
ATOM   1103 C CB  . PHE   A 1 157 ? 6.71852   3.03737   18.95378  1.000 21.42902 ?  137 PHE   A CB  1 
ATOM   1104 C CG  . PHE   A 1 157 ? 7.18112   2.95298   20.37638  1.000 22.36675 ?  137 PHE   A CG  1 
ATOM   1105 C CD1 . PHE   A 1 157 ? 7.11912   4.06199   21.20356  1.000 21.46047 ?  137 PHE   A CD1 1 
ATOM   1106 C CD2 . PHE   A 1 157 ? 7.70856   1.77599   20.87776  1.000 25.27979 ?  137 PHE   A CD2 1 
ATOM   1107 C CE1 . PHE   A 1 157 ? 7.55868   3.99246   22.51251  1.000 25.90007 ?  137 PHE   A CE1 1 
ATOM   1108 C CE2 . PHE   A 1 157 ? 8.14903   1.70078   22.18492  1.000 24.63526 ?  137 PHE   A CE2 1 
ATOM   1109 C CZ  . PHE   A 1 157 ? 8.07396   2.81137   23.00205  1.000 21.75015 ?  137 PHE   A CZ  1 
ATOM   1110 N N   . PRO   A 1 158 ? 10.05132  3.00697   18.42196  1.000 20.29752 ?  138 PRO   A N   1 
ATOM   1111 C CA  . PRO   A 1 158 ? 11.25218  2.18247   18.16468  1.000 20.98223 ?  138 PRO   A CA  1 
ATOM   1112 C C   . PRO   A 1 158 ? 11.17500  0.81152   18.83260  1.000 26.76876 ?  138 PRO   A C   1 
ATOM   1113 O O   . PRO   A 1 158 ? 11.74002  0.54677   19.89319  1.000 29.58185 ?  138 PRO   A O   1 
ATOM   1114 C CB  . PRO   A 1 158 ? 12.37630  3.04499   18.74234  1.000 24.60530 ?  138 PRO   A CB  1 
ATOM   1115 C CG  . PRO   A 1 158 ? 11.72454  3.76580   19.87690  1.000 23.69491 ?  138 PRO   A CG  1 
ATOM   1116 C CD  . PRO   A 1 158 ? 10.30257  4.03961   19.44333  1.000 25.15814 ?  138 PRO   A CD  1 
ATOM   1117 N N   . TRP   A 1 159 ? 10.44786  -0.10070  18.18330  1.000 27.67170 ?  139 TRP   A N   1 
ATOM   1118 C CA  . TRP   A 1 159 ? 10.24734  -1.43065  18.74592  1.000 22.61334 ?  139 TRP   A CA  1 
ATOM   1119 C C   . TRP   A 1 159 ? 11.53175  -2.24869  18.79297  1.000 29.24815 ?  139 TRP   A C   1 
ATOM   1120 O O   . TRP   A 1 159 ? 11.61774  -3.19015  19.58793  1.000 27.12031 ?  139 TRP   A O   1 
ATOM   1121 C CB  . TRP   A 1 159 ? 9.17456   -2.18244  17.95237  1.000 25.78363 ?  139 TRP   A CB  1 
ATOM   1122 C CG  . TRP   A 1 159 ? 7.83186   -1.51300  17.97472  1.000 22.03725 ?  139 TRP   A CG  1 
ATOM   1123 C CD1 . TRP   A 1 159 ? 7.18799   -0.93322  16.92051  1.000 23.64257 ?  139 TRP   A CD1 1 
ATOM   1124 C CD2 . TRP   A 1 159 ? 6.97198   -1.34791  19.10982  1.000 21.88531 ?  139 TRP   A CD2 1 
ATOM   1125 N NE1 . TRP   A 1 159 ? 5.97891   -0.42209  17.32715  1.000 20.68809 ?  139 TRP   A NE1 1 
ATOM   1126 C CE2 . TRP   A 1 159 ? 5.82269   -0.66304  18.66689  1.000 21.58537 ?  139 TRP   A CE2 1 
ATOM   1127 C CE3 . TRP   A 1 159 ? 7.06167   -1.71414  20.45644  1.000 22.98153 ?  139 TRP   A CE3 1 
ATOM   1128 C CZ2 . TRP   A 1 159 ? 4.77099   -0.33719  19.52217  1.000 19.30647 ?  139 TRP   A CZ2 1 
ATOM   1129 C CZ3 . TRP   A 1 159 ? 6.01702   -1.38837  21.30416  1.000 20.87975 ?  139 TRP   A CZ3 1 
ATOM   1130 C CH2 . TRP   A 1 159 ? 4.88711   -0.70683  20.83335  1.000 18.41013 ?  139 TRP   A CH2 1 
ATOM   1131 N N   . ASP   A 1 160 ? 12.52648  -1.91505  17.97384  1.000 27.97785 ?  140 ASP   A N   1 
ATOM   1132 C CA  . ASP   A 1 160 ? 13.79849  -2.62358  17.97204  1.000 33.20165 ?  140 ASP   A CA  1 
ATOM   1133 C C   . ASP   A 1 160 ? 14.81171  -2.03643  18.94963  1.000 31.59920 ?  140 ASP   A C   1 
ATOM   1134 O O   . ASP   A 1 160 ? 15.97174  -2.46097  18.94495  1.000 34.69528 ?  140 ASP   A O   1 
ATOM   1135 C CB  . ASP   A 1 160 ? 14.39387  -2.64809  16.55953  1.000 31.61543 ?  140 ASP   A CB  1 
ATOM   1136 C CG  . ASP   A 1 160 ? 14.96142  -1.30273  16.12934  1.000 36.84738 ?  140 ASP   A CG  1 
ATOM   1137 O OD1 . ASP   A 1 160 ? 14.62795  -0.26931  16.74608  1.000 35.06855 ?  140 ASP   A OD1 1 
ATOM   1138 O OD2 . ASP   A 1 160 ? 15.75303  -1.28352  15.16219  1.000 40.67951 ?  140 ASP   A OD2 1 
ATOM   1139 N N   . LEU   A 1 161 ? 14.40435  -1.07079  19.77858  1.000 32.92913 ?  141 LEU   A N   1 
ATOM   1140 C CA  . LEU   A 1 161 ? 15.34153  -0.45357  20.71167  1.000 34.20054 ?  141 LEU   A CA  1 
ATOM   1141 C C   . LEU   A 1 161 ? 15.91859  -1.48345  21.67378  1.000 34.06014 ?  141 LEU   A C   1 
ATOM   1142 O O   . LEU   A 1 161 ? 17.10540  -1.42871  22.01630  1.000 36.08141 ?  141 LEU   A O   1 
ATOM   1143 C CB  . LEU   A 1 161 ? 14.65092  0.67178   21.48071  1.000 30.33884 ?  141 LEU   A CB  1 
ATOM   1144 C CG  . LEU   A 1 161 ? 15.54987  1.46849   22.42493  1.000 32.34652 ?  141 LEU   A CG  1 
ATOM   1145 C CD1 . LEU   A 1 161 ? 16.61691  2.21598   21.63862  1.000 35.73962 ?  141 LEU   A CD1 1 
ATOM   1146 C CD2 . LEU   A 1 161 ? 14.73190  2.42508   23.27062  1.000 30.53819 ?  141 LEU   A CD2 1 
ATOM   1147 N N   . GLY   A 1 162 ? 15.09694  -2.42985  22.11664  1.000 29.90015 ?  142 GLY   A N   1 
ATOM   1148 C CA  . GLY   A 1 162 ? 15.53599  -3.49052  22.99405  1.000 33.83558 ?  142 GLY   A CA  1 
ATOM   1149 C C   . GLY   A 1 162 ? 15.95196  -4.76573  22.30420  1.000 41.67002 ?  142 GLY   A C   1 
ATOM   1150 O O   . GLY   A 1 162 ? 16.34139  -5.72419  22.97810  1.000 46.45358 ?  142 GLY   A O   1 
ATOM   1151 N N   . GLY   A 1 163 ? 15.88521  -4.81291  20.97327  1.000 43.34328 ?  143 GLY   A N   1 
ATOM   1152 C CA  . GLY   A 1 163 ? 16.28551  -6.00355  20.24369  1.000 44.80532 ?  143 GLY   A CA  1 
ATOM   1153 C C   . GLY   A 1 163 ? 17.76597  -6.31422  20.32049  1.000 51.51517 ?  143 GLY   A C   1 
ATOM   1154 O O   . GLY   A 1 163 ? 18.17590  -7.40064  19.89498  1.000 51.01863 ?  143 GLY   A O   1 
ATOM   1155 N N   . GLU   A 1 164 ? 18.57323  -5.39774  20.85360  1.000 49.10198 ?  144 GLU   A N   1 
ATOM   1156 C CA  . GLU   A 1 164 ? 20.01262  -5.60384  20.94600  1.000 48.89583 ?  144 GLU   A CA  1 
ATOM   1157 C C   . GLU   A 1 164 ? 20.41621  -6.35524  22.20914  1.000 55.79070 ?  144 GLU   A C   1 
ATOM   1158 O O   . GLU   A 1 164 ? 21.29515  -7.22179  22.15536  1.000 56.62584 ?  144 GLU   A O   1 
ATOM   1159 C CB  . GLU   A 1 164 ? 20.74096  -4.25836  20.88794  1.000 51.80109 ?  144 GLU   A CB  1 
ATOM   1160 N N   . ARG   A 1 165 ? 19.79622  -6.04698  23.34951  1.000 49.39981 ?  145 ARG   A N   1 
ATOM   1161 C CA  . ARG   A 1 165 ? 20.16256  -6.67877  24.61157  1.000 45.72064 ?  145 ARG   A CA  1 
ATOM   1162 C C   . ARG   A 1 165 ? 19.00566  -7.42370  25.27016  1.000 41.87564 ?  145 ARG   A C   1 
ATOM   1163 O O   . ARG   A 1 165 ? 19.11862  -7.80787  26.44054  1.000 36.54111 ?  145 ARG   A O   1 
ATOM   1164 C CB  . ARG   A 1 165 ? 20.76133  -5.64032  25.57167  1.000 50.51362 ?  145 ARG   A CB  1 
ATOM   1165 C CG  . ARG   A 1 165 ? 19.77717  -4.70968  26.27240  1.000 39.36913 ?  145 ARG   A CG  1 
ATOM   1166 C CD  . ARG   A 1 165 ? 20.47038  -4.05840  27.46779  1.000 44.15847 ?  145 ARG   A CD  1 
ATOM   1167 N NE  . ARG   A 1 165 ? 19.63805  -3.10039  28.18713  1.000 48.68793 ?  145 ARG   A NE  1 
ATOM   1168 C CZ  . ARG   A 1 165 ? 19.92507  -1.81175  28.31742  1.000 49.70106 ?  145 ARG   A CZ  1 
ATOM   1169 N NH1 . ARG   A 1 165 ? 21.00010  -1.28327  27.75620  1.000 53.30034 ?  145 ARG   A NH1 1 
ATOM   1170 N NH2 . ARG   A 1 165 ? 19.11491  -1.03419  29.03107  1.000 48.37115 ?  145 ARG   A NH2 1 
ATOM   1171 N N   . TYR   A 1 166 ? 17.90709  -7.65520  24.55071  1.000 45.06065 ?  146 TYR   A N   1 
ATOM   1172 C CA  . TYR   A 1 166 ? 16.83140  -8.52009  25.01856  1.000 38.20845 ?  146 TYR   A CA  1 
ATOM   1173 C C   . TYR   A 1 166 ? 16.40199  -9.44288  23.87738  1.000 42.38080 ?  146 TYR   A C   1 
ATOM   1174 O O   . TYR   A 1 166 ? 15.28730  -9.38206  23.37142  1.000 39.20439 ?  146 TYR   A O   1 
ATOM   1175 C CB  . TYR   A 1 166 ? 15.64465  -7.71529  25.54656  1.000 38.10382 ?  146 TYR   A CB  1 
ATOM   1176 C CG  . TYR   A 1 166 ? 15.99155  -6.73648  26.64644  1.000 36.46276 ?  146 TYR   A CG  1 
ATOM   1177 C CD1 . TYR   A 1 166 ? 16.45364  -7.18363  27.87590  1.000 33.68268 ?  146 TYR   A CD1 1 
ATOM   1178 C CD2 . TYR   A 1 166 ? 15.84464  -5.36776  26.46080  1.000 35.93747 ?  146 TYR   A CD2 1 
ATOM   1179 C CE1 . TYR   A 1 166 ? 16.77427  -6.29825  28.88755  1.000 36.88428 ?  146 TYR   A CE1 1 
ATOM   1180 C CE2 . TYR   A 1 166 ? 16.16006  -4.47286  27.46808  1.000 38.74282 ?  146 TYR   A CE2 1 
ATOM   1181 C CZ  . TYR   A 1 166 ? 16.62502  -4.94259  28.68022  1.000 37.27082 ?  146 TYR   A CZ  1 
ATOM   1182 O OH  . TYR   A 1 166 ? 16.94256  -4.05654  29.68699  1.000 31.03464 ?  146 TYR   A OH  1 
ATOM   1183 N N   . ARG   A 1 167 ? 17.30572  -10.32243 23.45837  1.000 44.17859 ?  147 ARG   A N   1 
ATOM   1184 C CA  . ARG   A 1 167 ? 17.05852  -11.23273 22.34772  1.000 46.17542 ?  147 ARG   A CA  1 
ATOM   1185 C C   . ARG   A 1 167 ? 16.85368  -12.64689 22.87320  1.000 49.53638 ?  147 ARG   A C   1 
ATOM   1186 O O   . ARG   A 1 167 ? 17.64477  -13.12999 23.69138  1.000 53.60313 ?  147 ARG   A O   1 
ATOM   1187 C CB  . ARG   A 1 167 ? 18.21146  -11.20135 21.34214  1.000 51.38097 ?  147 ARG   A CB  1 
ATOM   1188 N N   . TYR   A 1 168 ? 15.79518  -13.30209 22.39668  1.000 53.02420 ?  148 TYR   A N   1 
ATOM   1189 C CA  . TYR   A 1 168 ? 15.48188  -14.65404 22.81743  1.000 49.19117 ?  148 TYR   A CA  1 
ATOM   1190 C C   . TYR   A 1 168 ? 16.62885  -15.60255 22.47957  1.000 53.52605 ?  148 TYR   A C   1 
ATOM   1191 O O   . TYR   A 1 168 ? 17.55589  -15.28161 21.72794  1.000 55.80760 ?  148 TYR   A O   1 
ATOM   1192 C CB  . TYR   A 1 168 ? 14.19850  -15.14337 22.15004  1.000 48.16357 ?  148 TYR   A CB  1 
ATOM   1193 C CG  . TYR   A 1 168 ? 12.93262  -14.92531 22.95438  1.000 48.81219 ?  148 TYR   A CG  1 
ATOM   1194 C CD1 . TYR   A 1 168 ? 12.90582  -15.12556 24.33061  1.000 48.12414 ?  148 TYR   A CD1 1 
ATOM   1195 C CD2 . TYR   A 1 168 ? 11.75802  -14.52841 22.32938  1.000 51.02537 ?  148 TYR   A CD2 1 
ATOM   1196 C CE1 . TYR   A 1 168 ? 11.74363  -14.92925 25.06064  1.000 43.95417 ?  148 TYR   A CE1 1 
ATOM   1197 C CE2 . TYR   A 1 168 ? 10.59702  -14.33010 23.04978  1.000 45.65753 ?  148 TYR   A CE2 1 
ATOM   1198 C CZ  . TYR   A 1 168 ? 10.58999  -14.53045 24.41168  1.000 46.31360 ?  148 TYR   A CZ  1 
ATOM   1199 O OH  . TYR   A 1 168 ? 9.42527   -14.33059 25.12354  1.000 46.11449 ?  148 TYR   A OH  1 
ATOM   1200 N N   . ALA   A 1 169 ? 16.55327  -16.79130 23.06082  1.000 66.71736 ?  149 ALA   A N   1 
ATOM   1201 C CA  . ALA   A 1 169 ? 17.53592  -17.84472 22.82008  1.000 64.10952 ?  149 ALA   A CA  1 
ATOM   1202 C C   . ALA   A 1 169 ? 17.22971  -18.56713 21.51010  1.000 61.10957 ?  149 ALA   A C   1 
ATOM   1203 O O   . ALA   A 1 169 ? 17.15630  -19.78956 21.47024  1.000 72.11296 ?  149 ALA   A O   1 
ATOM   1204 C CB  . ALA   A 1 169 ? 17.54910  -18.82895 23.97882  1.000 58.89297 ?  149 ALA   A CB  1 
ATOM   1205 N N   . ARG   A 1 199 ? -19.05674 -13.43546 -1.71124  1.000 34.94331 ?  179 ARG   A N   1 
ATOM   1206 C CA  . ARG   A 1 199 ? -17.68789 -13.36013 -2.21010  1.000 36.50610 ?  179 ARG   A CA  1 
ATOM   1207 C C   . ARG   A 1 199 ? -17.47396 -12.08968 -3.02173  1.000 37.97610 ?  179 ARG   A C   1 
ATOM   1208 O O   . ARG   A 1 199 ? -17.49307 -12.11571 -4.25089  1.000 38.82970 ?  179 ARG   A O   1 
ATOM   1209 C CB  . ARG   A 1 199 ? -17.35597 -14.58951 -3.05977  1.000 43.81554 ?  179 ARG   A CB  1 
ATOM   1210 C CG  . ARG   A 1 199 ? -17.28354 -15.88980 -2.27273  1.000 40.50209 ?  179 ARG   A CG  1 
ATOM   1211 C CD  . ARG   A 1 199 ? -16.72220 -15.65269 -0.88324  1.000 43.11256 ?  179 ARG   A CD  1 
ATOM   1212 N NE  . ARG   A 1 199 ? -16.58368 -16.88502 -0.11736  1.000 48.39598 ?  179 ARG   A NE  1 
ATOM   1213 C CZ  . ARG   A 1 199 ? -17.19979 -17.12963 1.03107   1.000 42.44923 ?  179 ARG   A CZ  1 
ATOM   1214 N NH1 . ARG   A 1 199 ? -18.04019 -16.25773 1.56555   1.000 43.04839 ?  179 ARG   A NH1 1 
ATOM   1215 N NH2 . ARG   A 1 199 ? -16.95441 -18.27120 1.66688   1.000 45.50888 ?  179 ARG   A NH2 1 
ATOM   1216 N N   . ILE   A 1 200 ? -17.26517 -10.96992 -2.32465  1.000 34.90359 ?  180 ILE   A N   1 
ATOM   1217 C CA  . ILE   A 1 200 ? -17.11165 -9.67125  -2.95002  1.000 32.51546 ?  180 ILE   A CA  1 
ATOM   1218 C C   . ILE   A 1 200 ? -15.64348 -9.50094  -3.33342  1.000 33.73967 ?  180 ILE   A C   1 
ATOM   1219 O O   . ILE   A 1 200 ? -14.78632 -9.44864  -2.43193  1.000 34.83587 ?  180 ILE   A O   1 
ATOM   1220 C CB  . ILE   A 1 200 ? -17.57424 -8.53889  -2.02148  1.000 31.83000 ?  180 ILE   A CB  1 
ATOM   1221 C CG1 . ILE   A 1 200 ? -18.97384 -8.83743  -1.47874  1.000 35.49801 ?  180 ILE   A CG1 1 
ATOM   1222 C CG2 . ILE   A 1 200 ? -17.55087 -7.20881  -2.74820  1.000 31.78090 ?  180 ILE   A CG2 1 
ATOM   1223 C CD1 . ILE   A 1 200 ? -20.05689 -8.82199  -2.53659  1.000 42.76112 ?  180 ILE   A CD1 1 
ATOM   1224 N N   . PRO   A 1 201 ? -15.30487 -9.42329  -4.61959  1.000 33.28276 ?  181 PRO   A N   1 
ATOM   1225 C CA  . PRO   A 1 201 ? -13.89633 -9.27118  -5.00027  1.000 28.89853 ?  181 PRO   A CA  1 
ATOM   1226 C C   . PRO   A 1 201 ? -13.37290 -7.88993  -4.63928  1.000 31.63750 ?  181 PRO   A C   1 
ATOM   1227 O O   . PRO   A 1 201 ? -14.02725 -6.87254  -4.88145  1.000 27.04896 ?  181 PRO   A O   1 
ATOM   1228 C CB  . PRO   A 1 201 ? -13.89935 -9.48164  -6.51956  1.000 30.55724 ?  181 PRO   A CB  1 
ATOM   1229 C CG  . PRO   A 1 201 ? -15.30933 -9.35592  -6.95012  1.000 32.99529 ?  181 PRO   A CG  1 
ATOM   1230 C CD  . PRO   A 1 201 ? -16.19722 -9.60627  -5.77805  1.000 31.65745 ?  181 PRO   A CD  1 
ATOM   1231 N N   . VAL   A 1 202 ? -12.17489 -7.86506  -4.05475  1.000 27.24387 ?  182 VAL   A N   1 
ATOM   1232 C CA  . VAL   A 1 202 ? -11.47967 -6.63109  -3.71209  1.000 27.16915 ?  182 VAL   A CA  1 
ATOM   1233 C C   . VAL   A 1 202 ? -10.01466 -6.78116  -4.10040  1.000 27.87515 ?  182 VAL   A C   1 
ATOM   1234 O O   . VAL   A 1 202 ? -9.54045  -7.87183  -4.42221  1.000 29.20295 ?  182 VAL   A O   1 
ATOM   1235 C CB  . VAL   A 1 202 ? -11.60455 -6.27695  -2.21505  1.000 27.39484 ?  182 VAL   A CB  1 
ATOM   1236 C CG1 . VAL   A 1 202 ? -13.01195 -5.80016  -1.89357  1.000 22.79465 ?  182 VAL   A CG1 1 
ATOM   1237 C CG2 . VAL   A 1 202 ? -11.23003 -7.47356  -1.35759  1.000 29.95379 ?  182 VAL   A CG2 1 
ATOM   1238 N N   . ARG   A 1 203 ? -9.29359  -5.66385  -4.05795  1.000 32.36264 ?  183 ARG   A N   1 
ATOM   1239 C CA  . ARG   A 1 203 ? -7.89558  -5.62401  -4.46324  1.000 30.90932 ?  183 ARG   A CA  1 
ATOM   1240 C C   . ARG   A 1 203 ? -7.06972  -4.92497  -3.39445  1.000 30.17475 ?  183 ARG   A C   1 
ATOM   1241 O O   . ARG   A 1 203 ? -7.42420  -3.82936  -2.94819  1.000 28.88923 ?  183 ARG   A O   1 
ATOM   1242 C CB  . ARG   A 1 203 ? -7.73644  -4.91121  -5.81049  1.000 32.80339 ?  183 ARG   A CB  1 
ATOM   1243 C CG  . ARG   A 1 203 ? -6.29858  -4.75555  -6.27010  1.000 30.13393 ?  183 ARG   A CG  1 
ATOM   1244 C CD  . ARG   A 1 203 ? -6.23417  -4.34234  -7.73124  1.000 37.62970 ?  183 ARG   A CD  1 
ATOM   1245 N NE  . ARG   A 1 203 ? -6.75005  -5.38153  -8.61453  1.000 40.56208 ?  183 ARG   A NE  1 
ATOM   1246 C CZ  . ARG   A 1 203 ? -6.63886  -5.36419  -9.93582  1.000 41.28511 ?  183 ARG   A CZ  1 
ATOM   1247 N NH1 . ARG   A 1 203 ? -6.04210  -4.36600  -10.56599 1.000 37.15958 ?  183 ARG   A NH1 1 
ATOM   1248 N NH2 . ARG   A 1 203 ? -7.13943  -6.37358  -10.64274 1.000 41.60304 ?  183 ARG   A NH2 1 
ATOM   1249 N N   . LEU   A 1 204 ? -5.97407  -5.56037  -2.98818  1.000 31.13527 ?  184 LEU   A N   1 
ATOM   1250 C CA  . LEU   A 1 204 ? -5.03818  -4.99842  -2.02549  1.000 31.00790 ?  184 LEU   A CA  1 
ATOM   1251 C C   . LEU   A 1 204 ? -3.72585  -4.67256  -2.72543  1.000 26.28887 ?  184 LEU   A C   1 
ATOM   1252 O O   . LEU   A 1 204 ? -3.21770  -5.47411  -3.51589  1.000 30.88957 ?  184 LEU   A O   1 
ATOM   1253 C CB  . LEU   A 1 204 ? -4.78750  -5.96573  -0.86293  1.000 28.38760 ?  184 LEU   A CB  1 
ATOM   1254 C CG  . LEU   A 1 204 ? -5.86141  -6.06883  0.22526   1.000 27.85532 ?  184 LEU   A CG  1 
ATOM   1255 C CD1 . LEU   A 1 204 ? -7.04242  -6.91238  -0.23425  1.000 32.31327 ?  184 LEU   A CD1 1 
ATOM   1256 C CD2 . LEU   A 1 204 ? -5.26954  -6.62779  1.51225   1.000 25.96906 ?  184 LEU   A CD2 1 
ATOM   1257 N N   . THR   A 1 205 ? -3.18157  -3.49302  -2.43457  1.000 23.05769 ?  185 THR   A N   1 
ATOM   1258 C CA  . THR   A 1 205 ? -1.95904  -3.02776  -3.07249  1.000 29.99750 ?  185 THR   A CA  1 
ATOM   1259 C C   . THR   A 1 205 ? -1.06235  -2.36997  -2.03550  1.000 26.10666 ?  185 THR   A C   1 
ATOM   1260 O O   . THR   A 1 205 ? -1.52763  -1.56731  -1.22150  1.000 24.10166 ?  185 THR   A O   1 
ATOM   1261 C CB  . THR   A 1 205 ? -2.25835  -2.03452  -4.20365  1.000 27.35085 ?  185 THR   A CB  1 
ATOM   1262 O OG1 . THR   A 1 205 ? -3.15659  -2.63523  -5.14347  1.000 31.84137 ?  185 THR   A OG1 1 
ATOM   1263 C CG2 . THR   A 1 205 ? -0.97804  -1.64037  -4.92310  1.000 27.75540 ?  185 THR   A CG2 1 
ATOM   1264 N N   . TRP   A 1 206 ? 0.22425   -2.71233  -2.07411  1.000 24.64918 ?  186 TRP   A N   1 
ATOM   1265 C CA  . TRP   A 1 206 ? 1.22345   -2.15641  -1.16992  1.000 24.63890 ?  186 TRP   A CA  1 
ATOM   1266 C C   . TRP   A 1 206 ? 2.23620   -1.36301  -1.98156  1.000 29.82077 ?  186 TRP   A C   1 
ATOM   1267 O O   . TRP   A 1 206 ? 2.87949   -1.91059  -2.88336  1.000 31.59333 ?  186 TRP   A O   1 
ATOM   1268 C CB  . TRP   A 1 206 ? 1.92282   -3.26009  -0.37307  1.000 25.22823 ?  186 TRP   A CB  1 
ATOM   1269 C CG  . TRP   A 1 206 ? 1.01652   -3.98396  0.57174   1.000 20.55510 ?  186 TRP   A CG  1 
ATOM   1270 C CD1 . TRP   A 1 206 ? 0.74843   -3.65274  1.86745   1.000 22.63946 ?  186 TRP   A CD1 1 
ATOM   1271 C CD2 . TRP   A 1 206 ? 0.25462   -5.16388  0.29327   1.000 23.88154 ?  186 TRP   A CD2 1 
ATOM   1272 N NE1 . TRP   A 1 206 ? -0.13282  -4.55421  2.41409   1.000 26.64439 ?  186 TRP   A NE1 1 
ATOM   1273 C CE2 . TRP   A 1 206 ? -0.45176  -5.49173  1.46742   1.000 23.52103 ?  186 TRP   A CE2 1 
ATOM   1274 C CE3 . TRP   A 1 206 ? 0.10097   -5.97463  -0.83487  1.000 22.46615 ?  186 TRP   A CE3 1 
ATOM   1275 C CZ2 . TRP   A 1 206 ? -1.29725  -6.59545  1.54568   1.000 22.52799 ?  186 TRP   A CZ2 1 
ATOM   1276 C CZ3 . TRP   A 1 206 ? -0.73805  -7.06830  -0.75524  1.000 25.77871 ?  186 TRP   A CZ3 1 
ATOM   1277 C CH2 . TRP   A 1 206 ? -1.42711  -7.36922  0.42595   1.000 25.36763 ?  186 TRP   A CH2 1 
ATOM   1278 N N   . GLN   A 1 207 ? 2.37590   -0.07957  -1.65968  1.000 28.71220 ?  187 GLN   A N   1 
ATOM   1279 C CA  . GLN   A 1 207 ? 3.35685   0.79342   -2.27921  1.000 33.96139 ?  187 GLN   A CA  1 
ATOM   1280 C C   . GLN   A 1 207 ? 4.31190   1.33314   -1.21978  1.000 36.83295 ?  187 GLN   A C   1 
ATOM   1281 O O   . GLN   A 1 207 ? 3.91888   1.51011   -0.06198  1.000 32.25052 ?  187 GLN   A O   1 
ATOM   1282 C CB  . GLN   A 1 207 ? 2.67624   1.95872   -3.01015  1.000 28.04487 ?  187 GLN   A CB  1 
ATOM   1283 C CG  . GLN   A 1 207 ? 1.72504   1.51975   -4.11481  1.000 32.57061 ?  187 GLN   A CG  1 
ATOM   1284 C CD  . GLN   A 1 207 ? 2.44986   1.06980   -5.37048  1.000 38.67789 ?  187 GLN   A CD  1 
ATOM   1285 O OE1 . GLN   A 1 207 ? 3.67656   1.13613   -5.45271  1.000 36.60521 ?  187 GLN   A OE1 1 
ATOM   1286 N NE2 . GLN   A 1 207 ? 1.69119   0.60420   -6.35578  1.000 33.42882 ?  187 GLN   A NE2 1 
ATOM   1287 N N   . PRO   A 1 208 ? 5.57649   1.61098   -1.58083  1.000 39.08545 ?  188 PRO   A N   1 
ATOM   1288 C CA  . PRO   A 1 208 ? 6.15452   1.57139   -2.92887  1.000 38.20022 ?  188 PRO   A CA  1 
ATOM   1289 C C   . PRO   A 1 208 ? 6.61622   0.18417   -3.37485  1.000 38.88199 ?  188 PRO   A C   1 
ATOM   1290 O O   . PRO   A 1 208 ? 7.32631   0.07652   -4.37516  1.000 43.33340 ?  188 PRO   A O   1 
ATOM   1291 C CB  . PRO   A 1 208 ? 7.34768   2.51583   -2.80662  1.000 44.02428 ?  188 PRO   A CB  1 
ATOM   1292 C CG  . PRO   A 1 208 ? 7.80700   2.33095   -1.39064  1.000 40.03542 ?  188 PRO   A CG  1 
ATOM   1293 C CD  . PRO   A 1 208 ? 6.59732   1.93265   -0.56719  1.000 38.78387 ?  188 PRO   A CD  1 
ATOM   1294 N N   . LEU   A 1 209 ? 6.21642   -0.85713  -2.64016  1.000 39.76086 ?  189 LEU   A N   1 
ATOM   1295 C CA  . LEU   A 1 209 ? 6.62242   -2.21408  -2.99538  1.000 37.21486 ?  189 LEU   A CA  1 
ATOM   1296 C C   . LEU   A 1 209 ? 6.13861   -2.59336  -4.38978  1.000 39.17115 ?  189 LEU   A C   1 
ATOM   1297 O O   . LEU   A 1 209 ? 6.84488   -3.28583  -5.13352  1.000 36.22451 ?  189 LEU   A O   1 
ATOM   1298 C CB  . LEU   A 1 209 ? 6.09651   -3.21050  -1.96125  1.000 40.46355 ?  189 LEU   A CB  1 
ATOM   1299 C CG  . LEU   A 1 209 ? 6.89285   -3.42359  -0.67206  1.000 42.13740 ?  189 LEU   A CG  1 
ATOM   1300 C CD1 . LEU   A 1 209 ? 6.82038   -2.21013  0.24594   1.000 42.65063 ?  189 LEU   A CD1 1 
ATOM   1301 C CD2 . LEU   A 1 209 ? 6.39311   -4.66982  0.04157   1.000 34.55511 ?  189 LEU   A CD2 1 
ATOM   1302 N N   . GLY   A 1 210 ? 4.94096   -2.14741  -4.76308  1.000 38.99119 ?  190 GLY   A N   1 
ATOM   1303 C CA  . GLY   A 1 210 ? 4.37271   -2.50426  -6.04470  1.000 33.45393 ?  190 GLY   A CA  1 
ATOM   1304 C C   . GLY   A 1 210 ? 3.65909   -3.83527  -6.07865  1.000 37.22466 ?  190 GLY   A C   1 
ATOM   1305 O O   . GLY   A 1 210 ? 3.24407   -4.27005  -7.15927  1.000 41.74926 ?  190 GLY   A O   1 
ATOM   1306 N N   . VAL   A 1 211 ? 3.49980   -4.49464  -4.93576  1.000 31.70568 ?  191 VAL   A N   1 
ATOM   1307 C CA  . VAL   A 1 211 ? 2.84629   -5.79658  -4.88293  1.000 26.47065 ?  191 VAL   A CA  1 
ATOM   1308 C C   . VAL   A 1 211 ? 1.33727   -5.60406  -4.92291  1.000 29.61461 ?  191 VAL   A C   1 
ATOM   1309 O O   . VAL   A 1 211 ? 0.78566   -4.72932  -4.24492  1.000 32.22265 ?  191 VAL   A O   1 
ATOM   1310 C CB  . VAL   A 1 211 ? 3.27813   -6.56669  -3.62207  1.000 27.61824 ?  191 VAL   A CB  1 
ATOM   1311 C CG1 . VAL   A 1 211 ? 2.58140   -7.91995  -3.55776  1.000 21.88194 ?  191 VAL   A CG1 1 
ATOM   1312 C CG2 . VAL   A 1 211 ? 4.79133   -6.72652  -3.58575  1.000 25.99662 ?  191 VAL   A CG2 1 
ATOM   1313 N N   . GLN   A 1 212 ? 0.66297   -6.42625  -5.72076  1.000 31.62916 ?  192 GLN   A N   1 
ATOM   1314 C CA  . GLN   A 1 212 ? -0.78291  -6.37467  -5.87246  1.000 31.06729 ?  192 GLN   A CA  1 
ATOM   1315 C C   . GLN   A 1 212 ? -1.34995  -7.78254  -5.78817  1.000 31.21798 ?  192 GLN   A C   1 
ATOM   1316 O O   . GLN   A 1 212 ? -0.80876  -8.71526  -6.38945  1.000 30.32447 ?  192 GLN   A O   1 
ATOM   1317 C CB  . GLN   A 1 212 ? -1.18095  -5.73353  -7.20570  1.000 33.30432 ?  192 GLN   A CB  1 
ATOM   1318 C CG  . GLN   A 1 212 ? -2.59292  -5.17992  -7.23062  1.000 32.28484 ?  192 GLN   A CG  1 
ATOM   1319 C CD  . GLN   A 1 212 ? -2.83013  -4.25070  -8.40307  1.000 30.98502 ?  192 GLN   A CD  1 
ATOM   1320 O OE1 . GLN   A 1 212 ? -3.35076  -4.66039  -9.44062  1.000 33.05417 ?  192 GLN   A OE1 1 
ATOM   1321 N NE2 . GLN   A 1 212 ? -2.44604  -2.98996  -8.24425  1.000 35.40523 ?  192 GLN   A NE2 1 
ATOM   1322 N N   . VAL   A 1 213 ? -2.43904  -7.93344  -5.03587  1.000 32.93869 ?  193 VAL   A N   1 
ATOM   1323 C CA  . VAL   A 1 213 ? -3.10208  -9.22030  -4.87387  1.000 28.78405 ?  193 VAL   A CA  1 
ATOM   1324 C C   . VAL   A 1 213 ? -4.60583  -9.02560  -5.00266  1.000 36.98209 ?  193 VAL   A C   1 
ATOM   1325 O O   . VAL   A 1 213 ? -5.15166  -7.97666  -4.64677  1.000 36.76973 ?  193 VAL   A O   1 
ATOM   1326 C CB  . VAL   A 1 213 ? -2.76384  -9.88716  -3.51912  1.000 31.99124 ?  193 VAL   A CB  1 
ATOM   1327 C CG1 . VAL   A 1 213 ? -1.28486  -10.24171 -3.44436  1.000 28.04826 ?  193 VAL   A CG1 1 
ATOM   1328 C CG2 . VAL   A 1 213 ? -3.16630  -8.98512  -2.36178  1.000 28.42889 ?  193 VAL   A CG2 1 
ATOM   1329 N N   . ASP   A 1 214 ? -5.27192  -10.04540 -5.53130  1.000 33.17014 ?  194 ASP   A N   1 
ATOM   1330 C CA  . ASP   A 1 214 ? -6.72271  -10.11957 -5.50274  1.000 28.36638 ?  194 ASP   A CA  1 
ATOM   1331 C C   . ASP   A 1 214 ? -7.16270  -10.83210 -4.23130  1.000 30.93370 ?  194 ASP   A C   1 
ATOM   1332 O O   . ASP   A 1 214 ? -6.46426  -11.70881 -3.71529  1.000 30.34597 ?  194 ASP   A O   1 
ATOM   1333 C CB  . ASP   A 1 214 ? -7.26220  -10.85523 -6.73204  1.000 28.42642 ?  194 ASP   A CB  1 
ATOM   1334 C CG  . ASP   A 1 214 ? -7.15770  -10.03042 -8.00346  1.000 38.34887 ?  194 ASP   A CG  1 
ATOM   1335 O OD1 . ASP   A 1 214 ? -6.79697  -8.83835  -7.91830  1.000 33.84147 ?  194 ASP   A OD1 1 
ATOM   1336 O OD2 . ASP   A 1 214 ? -7.43147  -10.57960 -9.09244  1.000 50.31114 ?  194 ASP   A OD2 1 
ATOM   1337 N N   . ALA   A 1 215 ? -8.32656  -10.44105 -3.72169  1.000 27.70082 ?  195 ALA   A N   1 
ATOM   1338 C CA  . ALA   A 1 215 ? -8.84339  -11.00920 -2.48647  1.000 31.21539 ?  195 ALA   A CA  1 
ATOM   1339 C C   . ALA   A 1 215 ? -10.35833 -11.11616 -2.59237  1.000 32.03932 ?  195 ALA   A C   1 
ATOM   1340 O O   . ALA   A 1 215 ? -10.96383 -10.70951 -3.58789  1.000 33.94608 ?  195 ALA   A O   1 
ATOM   1341 C CB  . ALA   A 1 215 ? -8.42014  -10.17370 -1.27521  1.000 27.73999 ?  195 ALA   A CB  1 
ATOM   1342 N N   . GLU   A 1 216 ? -10.96969 -11.67551 -1.55057  1.000 28.69394 ?  196 GLU   A N   1 
ATOM   1343 C CA  . GLU   A 1 216 ? -12.41006 -11.90138 -1.51312  1.000 33.81969 ?  196 GLU   A CA  1 
ATOM   1344 C C   . GLU   A 1 216 ? -12.91286 -11.56775 -0.11953  1.000 28.27215 ?  196 GLU   A C   1 
ATOM   1345 O O   . GLU   A 1 216 ? -12.41223 -12.12142 0.86107   1.000 30.04531 ?  196 GLU   A O   1 
ATOM   1346 C CB  . GLU   A 1 216 ? -12.75387 -13.35422 -1.85963  1.000 35.37538 ?  196 GLU   A CB  1 
ATOM   1347 C CG  . GLU   A 1 216 ? -12.33486 -13.79479 -3.24951  1.000 42.78022 ?  196 GLU   A CG  1 
ATOM   1348 C CD  . GLU   A 1 216 ? -13.48678 -13.78898 -4.23107  1.000 47.18084 ?  196 GLU   A CD  1 
ATOM   1349 O OE1 . GLU   A 1 216 ? -14.39341 -12.94360 -4.08282  1.000 42.23938 ?  196 GLU   A OE1 1 
ATOM   1350 O OE2 . GLU   A 1 216 ? -13.48779 -14.63283 -5.15140  1.000 49.45928 ?  196 GLU   A OE2 1 
ATOM   1351 N N   . ILE   A 1 217 ? -13.89449 -10.67585 -0.02679  1.000 31.26091 ?  197 ILE   A N   1 
ATOM   1352 C CA  . ILE   A 1 217 ? -14.57166 -10.40095 1.23647   1.000 25.77728 ?  197 ILE   A CA  1 
ATOM   1353 C C   . ILE   A 1 217 ? -15.73204 -11.37502 1.38640   1.000 26.71111 ?  197 ILE   A C   1 
ATOM   1354 O O   . ILE   A 1 217 ? -16.56188 -11.50985 0.48030   1.000 30.39496 ?  197 ILE   A O   1 
ATOM   1355 C CB  . ILE   A 1 217 ? -15.06311 -8.94408  1.30126   1.000 28.14727 ?  197 ILE   A CB  1 
ATOM   1356 C CG1 . ILE   A 1 217 ? -13.89033 -7.96364  1.20819   1.000 29.06097 ?  197 ILE   A CG1 1 
ATOM   1357 C CG2 . ILE   A 1 217 ? -15.85547 -8.70420  2.57817   1.000 24.81461 ?  197 ILE   A CG2 1 
ATOM   1358 C CD1 . ILE   A 1 217 ? -12.78665 -8.22577  2.21417   1.000 32.12947 ?  197 ILE   A CD1 1 
ATOM   1359 N N   . TYR   A 1 218 ? -15.78872 -12.06434 2.52383   1.000 25.50731 ?  198 TYR   A N   1 
ATOM   1360 C CA  . TYR   A 1 218 ? -16.89457 -12.97353 2.82310   1.000 29.15983 ?  198 TYR   A CA  1 
ATOM   1361 C C   . TYR   A 1 218 ? -18.03212 -12.14348 3.40339   1.000 34.24348 ?  198 TYR   A C   1 
ATOM   1362 O O   . TYR   A 1 218 ? -18.01129 -11.77709 4.58033   1.000 34.60716 ?  198 TYR   A O   1 
ATOM   1363 C CB  . TYR   A 1 218 ? -16.46364 -14.07843 3.78313   1.000 31.57528 ?  198 TYR   A CB  1 
ATOM   1364 C CG  . TYR   A 1 218 ? -15.30432 -14.93337 3.31267   1.000 31.68401 ?  198 TYR   A CG  1 
ATOM   1365 C CD1 . TYR   A 1 218 ? -14.92219 -14.96085 1.97805   1.000 33.48785 ?  198 TYR   A CD1 1 
ATOM   1366 C CD2 . TYR   A 1 218 ? -14.60872 -15.73521 4.20729   1.000 37.66731 ?  198 TYR   A CD2 1 
ATOM   1367 C CE1 . TYR   A 1 218 ? -13.86859 -15.75095 1.55115   1.000 37.92283 ?  198 TYR   A CE1 1 
ATOM   1368 C CE2 . TYR   A 1 218 ? -13.55688 -16.52724 3.79106   1.000 36.30230 ?  198 TYR   A CE2 1 
ATOM   1369 C CZ  . TYR   A 1 218 ? -13.19070 -16.53183 2.46353   1.000 37.32432 ?  198 TYR   A CZ  1 
ATOM   1370 O OH  . TYR   A 1 218 ? -12.14351 -17.32360 2.05318   1.000 41.82390 ?  198 TYR   A OH  1 
ATOM   1371 N N   . ALA   A 1 219 ? -19.03180 -11.84678 2.57571   1.000 26.28810 ?  199 ALA   A N   1 
ATOM   1372 C CA  . ALA   A 1 219 ? -20.12314 -10.96955 2.97868   1.000 29.41463 ?  199 ALA   A CA  1 
ATOM   1373 C C   . ALA   A 1 219 ? -21.19279 -11.67290 3.80412   1.000 32.43774 ?  199 ALA   A C   1 
ATOM   1374 O O   . ALA   A 1 219 ? -22.13912 -11.01246 4.24669   1.000 30.73682 ?  199 ALA   A O   1 
ATOM   1375 C CB  . ALA   A 1 219 ? -20.76829 -10.33387 1.74461   1.000 28.71578 ?  199 ALA   A CB  1 
ATOM   1376 N N   . ASP   A 1 220 ? -21.07269 -12.98023 4.02939   1.000 30.65171 ?  200 ASP   A N   1 
ATOM   1377 C CA  . ASP   A 1 220 ? -22.10823 -13.73704 4.71998   1.000 35.00546 ?  200 ASP   A CA  1 
ATOM   1378 C C   . ASP   A 1 220 ? -21.71432 -14.20290 6.11265   1.000 32.58283 ?  200 ASP   A C   1 
ATOM   1379 O O   . ASP   A 1 220 ? -22.59558 -14.39003 6.95349   1.000 37.28341 ?  200 ASP   A O   1 
ATOM   1380 C CB  . ASP   A 1 220 ? -22.51695 -14.95945 3.88749   1.000 37.53421 ?  200 ASP   A CB  1 
ATOM   1381 C CG  . ASP   A 1 220 ? -21.52860 -16.10198 4.00528   1.000 50.34510 ?  200 ASP   A CG  1 
ATOM   1382 O OD1 . ASP   A 1 220 ? -20.31818 -15.86712 3.80360   1.000 48.86115 ?  200 ASP   A OD1 1 
ATOM   1383 O OD2 . ASP   A 1 220 ? -21.96225 -17.23490 4.30319   1.000 52.88335 ?  200 ASP   A OD2 1 
ATOM   1384 N N   . LEU   A 1 221 ? -20.42145 -14.39373 6.38137   1.000 32.91361 ?  201 LEU   A N   1 
ATOM   1385 C CA  . LEU   A 1 221 ? -20.00177 -14.89859 7.68556   1.000 31.29252 ?  201 LEU   A CA  1 
ATOM   1386 C C   . LEU   A 1 221 ? -20.27873 -13.87748 8.78181   1.000 30.85123 ?  201 LEU   A C   1 
ATOM   1387 O O   . LEU   A 1 221 ? -21.01366 -14.15391 9.73710   1.000 31.58372 ?  201 LEU   A O   1 
ATOM   1388 C CB  . LEU   A 1 221 ? -18.51953 -15.27109 7.64844   1.000 33.17571 ?  201 LEU   A CB  1 
ATOM   1389 C CG  . LEU   A 1 221 ? -18.18810 -16.43105 6.71100   1.000 41.40469 ?  201 LEU   A CG  1 
ATOM   1390 C CD1 . LEU   A 1 221 ? -16.72825 -16.83729 6.84601   1.000 32.53978 ?  201 LEU   A CD1 1 
ATOM   1391 C CD2 . LEU   A 1 221 ? -19.11836 -17.60634 6.97464   1.000 27.80078 ?  201 LEU   A CD2 1 
ATOM   1392 N N   . ASN   A 1 222 ? -19.68882 -12.68706 8.66261   1.000 25.13574 ?  202 ASN   A N   1 
ATOM   1393 C CA  . ASN   A 1 222 ? -19.96611 -11.55809 9.54658   1.000 28.49506 ?  202 ASN   A CA  1 
ATOM   1394 C C   . ASN   A 1 222 ? -20.59495 -10.47319 8.68047   1.000 27.72750 ?  202 ASN   A C   1 
ATOM   1395 O O   . ASN   A 1 222 ? -19.90273 -9.55242  8.22065   1.000 24.32624 ?  202 ASN   A O   1 
ATOM   1396 C CB  . ASN   A 1 222 ? -18.70102 -11.06700 10.24683  1.000 28.83014 ?  202 ASN   A CB  1 
ATOM   1397 C CG  . ASN   A 1 222 ? -17.98434 -12.17465 10.99538  1.000 25.29693 ?  202 ASN   A CG  1 
ATOM   1398 O OD1 . ASN   A 1 222 ? -18.44461 -12.63446 12.03899  1.000 23.13001 ?  202 ASN   A OD1 1 
ATOM   1399 N ND2 . ASN   A 1 222 ? -16.84804 -12.60767 10.46323  1.000 24.81024 ?  202 ASN   A ND2 1 
ATOM   1400 N N   . PRO   A 1 223 ? -21.90779 -10.55223 8.43744   1.000 34.55510 ?  203 PRO   A N   1 
ATOM   1401 C CA  . PRO   A 1 223 ? -22.51281 -9.69441  7.39816   1.000 28.40654 ?  203 PRO   A CA  1 
ATOM   1402 C C   . PRO   A 1 223 ? -22.34343 -8.20559  7.64870   1.000 23.15165 ?  203 PRO   A C   1 
ATOM   1403 O O   . PRO   A 1 223 ? -21.88542 -7.48023  6.75503   1.000 26.67933 ?  203 PRO   A O   1 
ATOM   1404 C CB  . PRO   A 1 223 ? -23.99364 -10.11227 7.41838   1.000 25.00129 ?  203 PRO   A CB  1 
ATOM   1405 C CG  . PRO   A 1 223 ? -24.17921 -10.90476 8.67721   1.000 32.47467 ?  203 PRO   A CG  1 
ATOM   1406 C CD  . PRO   A 1 223 ? -22.86365 -11.53062 8.97905   1.000 28.20843 ?  203 PRO   A CD  1 
ATOM   1407 N N   . GLN   A 1 224 ? -22.70736 -7.72272  8.84025   1.000 24.50156 ?  204 GLN   A N   1 
ATOM   1408 C CA  . GLN   A 1 224 ? -22.61582 -6.29061  9.10430   1.000 28.10043 ?  204 GLN   A CA  1 
ATOM   1409 C C   . GLN   A 1 224 ? -21.16812 -5.81724  9.13093   1.000 26.97995 ?  204 GLN   A C   1 
ATOM   1410 O O   . GLN   A 1 224 ? -20.88256 -4.68532  8.72321   1.000 24.62080 ?  204 GLN   A O   1 
ATOM   1411 C CB  . GLN   A 1 224 ? -23.31797 -5.94974  10.42052  1.000 27.32136 ?  204 GLN   A CB  1 
ATOM   1412 C CG  . GLN   A 1 224 ? -23.35168 -4.46214  10.74805  1.000 30.49047 ?  204 GLN   A CG  1 
ATOM   1413 C CD  . GLN   A 1 224 ? -24.27971 -3.67812  9.84164   1.000 39.40978 ?  204 GLN   A CD  1 
ATOM   1414 O OE1 . GLN   A 1 224 ? -23.86467 -2.72353  9.18374   1.000 37.53896 ?  204 GLN   A OE1 1 
ATOM   1415 N NE2 . GLN   A 1 224 ? -25.54586 -4.07776  9.80374   1.000 35.98693 ?  204 GLN   A NE2 1 
ATOM   1416 N N   . LEU   A 1 225 ? -20.24517 -6.66552  9.59272   1.000 23.40282 ?  205 LEU   A N   1 
ATOM   1417 C CA  . LEU   A 1 225 ? -18.83259 -6.29733  9.58916   1.000 27.64973 ?  205 LEU   A CA  1 
ATOM   1418 C C   . LEU   A 1 225 ? -18.31518 -6.12566  8.16675   1.000 23.75812 ?  205 LEU   A C   1 
ATOM   1419 O O   . LEU   A 1 225 ? -17.66910 -5.12073  7.84486   1.000 25.95046 ?  205 LEU   A O   1 
ATOM   1420 C CB  . LEU   A 1 225 ? -18.01141 -7.34886  10.33751  1.000 25.82924 ?  205 LEU   A CB  1 
ATOM   1421 C CG  . LEU   A 1 225 ? -16.48863 -7.15886  10.29254  1.000 28.45366 ?  205 LEU   A CG  1 
ATOM   1422 C CD1 . LEU   A 1 225 ? -16.07156 -5.86008  10.97427  1.000 24.98791 ?  205 LEU   A CD1 1 
ATOM   1423 C CD2 . LEU   A 1 225 ? -15.77301 -8.34744  10.92027  1.000 22.04906 ?  205 LEU   A CD2 1 
ATOM   1424 N N   . ALA   A 1 226 ? -18.58264 -7.10812  7.30184   1.000 24.36046 ?  206 ALA   A N   1 
ATOM   1425 C CA  . ALA   A 1 226 ? -18.16317 -7.00256  5.90910   1.000 25.24892 ?  206 ALA   A CA  1 
ATOM   1426 C C   . ALA   A 1 226 ? -18.79366 -5.79091  5.23859   1.000 24.72194 ?  206 ALA   A C   1 
ATOM   1427 O O   . ALA   A 1 226 ? -18.13091 -5.08380  4.47101   1.000 28.39544 ?  206 ALA   A O   1 
ATOM   1428 C CB  . ALA   A 1 226 ? -18.51783 -8.28512  5.15537   1.000 25.71021 ?  206 ALA   A CB  1 
ATOM   1429 N N   . THR   A 1 227 ? -20.07209 -5.53186  5.52389   1.000 22.47977 ?  207 THR   A N   1 
ATOM   1430 C CA  . THR   A 1 227 ? -20.72625 -4.34007  4.99467   1.000 26.66101 ?  207 THR   A CA  1 
ATOM   1431 C C   . THR   A 1 227 ? -19.99997 -3.07841  5.44481   1.000 26.43296 ?  207 THR   A C   1 
ATOM   1432 O O   . THR   A 1 227 ? -19.76333 -2.16371  4.64652   1.000 26.26626 ?  207 THR   A O   1 
ATOM   1433 C CB  . THR   A 1 227 ? -22.19219 -4.30966  5.43540   1.000 27.12095 ?  207 THR   A CB  1 
ATOM   1434 O OG1 . THR   A 1 227 ? -22.95362 -5.22658  4.63972   1.000 37.61332 ?  207 THR   A OG1 1 
ATOM   1435 C CG2 . THR   A 1 227 ? -22.77564 -2.90817  5.28474   1.000 35.91449 ?  207 THR   A CG2 1 
ATOM   1436 N N   . ASP   A 1 228 ? -19.61499 -3.02657  6.72257   1.000 28.21870 ?  208 ASP   A N   1 
ATOM   1437 C CA  . ASP   A 1 228 ? -18.93503 -1.84904  7.25366   1.000 25.67737 ?  208 ASP   A CA  1 
ATOM   1438 C C   . ASP   A 1 228 ? -17.59599 -1.62665  6.55982   1.000 21.65609 ?  208 ASP   A C   1 
ATOM   1439 O O   . ASP   A 1 228 ? -17.25609 -0.49755  6.18794   1.000 23.71341 ?  208 ASP   A O   1 
ATOM   1440 C CB  . ASP   A 1 228 ? -18.74195 -1.99764  8.76365   1.000 23.23054 ?  208 ASP   A CB  1 
ATOM   1441 C CG  . ASP   A 1 228 ? -20.01868 -1.74850  9.54473   1.000 25.77162 ?  208 ASP   A CG  1 
ATOM   1442 O OD1 . ASP   A 1 228 ? -20.99652 -1.24502  8.95175   1.000 31.97148 ?  208 ASP   A OD1 1 
ATOM   1443 O OD2 . ASP   A 1 228 ? -20.04310 -2.05874  10.75424  1.000 25.13632 ?  208 ASP   A OD2 1 
ATOM   1444 N N   . VAL   A 1 229 ? -16.82107 -2.69789  6.37509   1.000 22.01815 ?  209 VAL   A N   1 
ATOM   1445 C CA  . VAL   A 1 229 ? -15.52025 -2.57012  5.72592   1.000 23.00463 ?  209 VAL   A CA  1 
ATOM   1446 C C   . VAL   A 1 229 ? -15.69196 -2.22479  4.25088   1.000 27.95673 ?  209 VAL   A C   1 
ATOM   1447 O O   . VAL   A 1 229 ? -14.98150 -1.36484  3.71444   1.000 22.31319 ?  209 VAL   A O   1 
ATOM   1448 C CB  . VAL   A 1 229 ? -14.70092 -3.85957  5.92275   1.000 19.12003 ?  209 VAL   A CB  1 
ATOM   1449 C CG1 . VAL   A 1 229 ? -13.47657 -3.86328  5.02022   1.000 21.56909 ?  209 VAL   A CG1 1 
ATOM   1450 C CG2 . VAL   A 1 229 ? -14.29221 -4.01280  7.38358   1.000 22.90321 ?  209 VAL   A CG2 1 
ATOM   1451 N N   . LEU   A 1 230 ? -16.64213 -2.88080  3.57464   1.000 23.02969 ?  210 LEU   A N   1 
ATOM   1452 C CA  . LEU   A 1 230 ? -16.91517 -2.56656  2.17494   1.000 22.30776 ?  210 LEU   A CA  1 
ATOM   1453 C C   . LEU   A 1 230 ? -17.32401 -1.11076  1.99800   1.000 26.29958 ?  210 LEU   A C   1 
ATOM   1454 O O   . LEU   A 1 230 ? -17.00931 -0.49783  0.97092   1.000 24.03772 ?  210 LEU   A O   1 
ATOM   1455 C CB  . LEU   A 1 230 ? -18.01048 -3.48842  1.63181   1.000 21.79664 ?  210 LEU   A CB  1 
ATOM   1456 C CG  . LEU   A 1 230 ? -17.62575 -4.93630  1.31084   1.000 23.83877 ?  210 LEU   A CG  1 
ATOM   1457 C CD1 . LEU   A 1 230 ? -18.85767 -5.73651  0.91011   1.000 24.29265 ?  210 LEU   A CD1 1 
ATOM   1458 C CD2 . LEU   A 1 230 ? -16.56892 -4.98315  0.22246   1.000 25.35620 ?  210 LEU   A CD2 1 
ATOM   1459 N N   . LYS   A 1 231 ? -18.00923 -0.53753  2.99176   1.000 25.39603 ?  211 LYS   A N   1 
ATOM   1460 C CA  . LYS   A 1 231 ? -18.44299 0.85143   2.88974   1.000 24.44271 ?  211 LYS   A CA  1 
ATOM   1461 C C   . LYS   A 1 231 ? -17.26549 1.81638   2.93965   1.000 31.52728 ?  211 LYS   A C   1 
ATOM   1462 O O   . LYS   A 1 231 ? -17.35383 2.92886   2.40709   1.000 25.64430 ?  211 LYS   A O   1 
ATOM   1463 C CB  . LYS   A 1 231 ? -19.43069 1.17395   4.00988   1.000 28.89905 ?  211 LYS   A CB  1 
ATOM   1464 C CG  . LYS   A 1 231 ? -20.85095 1.44681   3.54496   1.000 36.88643 ?  211 LYS   A CG  1 
ATOM   1465 C CD  . LYS   A 1 231 ? -21.84194 1.26087   4.68572   1.000 42.57394 ?  211 LYS   A CD  1 
ATOM   1466 C CE  . LYS   A 1 231 ? -23.14160 0.64115   4.20002   1.000 40.33415 ?  211 LYS   A CE  1 
ATOM   1467 N NZ  . LYS   A 1 231 ? -24.14260 0.51993   5.29614   1.000 39.70295 ?  211 LYS   A NZ  1 
ATOM   1468 N N   . ALA   A 1 232 ? -16.16506 1.41599   3.57360   1.000 26.81540 ?  212 ALA   A N   1 
ATOM   1469 C CA  . ALA   A 1 232 ? -14.99757 2.27531   3.72029   1.000 26.01093 ?  212 ALA   A CA  1 
ATOM   1470 C C   . ALA   A 1 232 ? -14.08285 2.25440   2.50328   1.000 24.79653 ?  212 ALA   A C   1 
ATOM   1471 O O   . ALA   A 1 232 ? -13.08750 2.98619   2.48680   1.000 26.12024 ?  212 ALA   A O   1 
ATOM   1472 C CB  . ALA   A 1 232 ? -14.20276 1.87123   4.96550   1.000 25.93236 ?  212 ALA   A CB  1 
ATOM   1473 N N   . LEU   A 1 233 ? -14.39130 1.44619   1.49138   1.000 23.39945 ?  213 LEU   A N   1 
ATOM   1474 C CA  . LEU   A 1 233 ? -13.53391 1.33623   0.31797   1.000 21.24806 ?  213 LEU   A CA  1 
ATOM   1475 C C   . LEU   A 1 233 ? -13.87698 2.41998   -0.70059  1.000 26.39071 ?  213 LEU   A C   1 
ATOM   1476 O O   . LEU   A 1 233 ? -15.05188 2.75624   -0.87682  1.000 27.85194 ?  213 LEU   A O   1 
ATOM   1477 C CB  . LEU   A 1 233 ? -13.68093 -0.03632  -0.33043  1.000 24.27835 ?  213 LEU   A CB  1 
ATOM   1478 C CG  . LEU   A 1 233 ? -13.34031 -1.22493  0.56667   1.000 25.75173 ?  213 LEU   A CG  1 
ATOM   1479 C CD1 . LEU   A 1 233 ? -13.41914 -2.52680  -0.21192  1.000 31.50698 ?  213 LEU   A CD1 1 
ATOM   1480 C CD2 . LEU   A 1 233 ? -11.96459 -1.04220  1.18046   1.000 23.98863 ?  213 LEU   A CD2 1 
ATOM   1481 N N   . PRO   A 1 234 ? -12.86927 2.98022   -1.38835  1.000 26.30395 ?  214 PRO   A N   1 
ATOM   1482 C CA  . PRO   A 1 234 ? -11.45301 2.64128   -1.20990  1.000 25.45541 ?  214 PRO   A CA  1 
ATOM   1483 C C   . PRO   A 1 234 ? -10.77177 3.47157   -0.12582  1.000 21.79410 ?  214 PRO   A C   1 
ATOM   1484 O O   . PRO   A 1 234 ? -11.24943 4.55857   0.19800   1.000 21.92127 ?  214 PRO   A O   1 
ATOM   1485 C CB  . PRO   A 1 234 ? -10.85791 2.96009   -2.57887  1.000 25.87093 ?  214 PRO   A CB  1 
ATOM   1486 C CG  . PRO   A 1 234 ? -11.65716 4.13875   -3.02771  1.000 23.81870 ?  214 PRO   A CG  1 
ATOM   1487 C CD  . PRO   A 1 234 ? -13.06809 3.88585   -2.53520  1.000 23.14623 ?  214 PRO   A CD  1 
ATOM   1488 N N   . PHE   A 1 235 ? -9.67180  2.96575   0.42969   1.000 25.16707 ?  215 PHE   A N   1 
ATOM   1489 C CA  . PHE   A 1 235 ? -8.86696  3.75394   1.35124   1.000 23.82598 ?  215 PHE   A CA  1 
ATOM   1490 C C   . PHE   A 1 235 ? -7.40447  3.36888   1.19100   1.000 24.43548 ?  215 PHE   A C   1 
ATOM   1491 O O   . PHE   A 1 235 ? -7.07375  2.27539   0.72410   1.000 24.08650 ?  215 PHE   A O   1 
ATOM   1492 C CB  . PHE   A 1 235 ? -9.32113  3.58718   2.81356   1.000 19.19396 ?  215 PHE   A CB  1 
ATOM   1493 C CG  . PHE   A 1 235 ? -9.22374  2.17577   3.34515   1.000 21.44262 ?  215 PHE   A CG  1 
ATOM   1494 C CD1 . PHE   A 1 235 ? -8.00534  1.64494   3.74556   1.000 19.03175 ?  215 PHE   A CD1 1 
ATOM   1495 C CD2 . PHE   A 1 235 ? -10.36027 1.39570   3.48287   1.000 21.65134 ?  215 PHE   A CD2 1 
ATOM   1496 C CE1 . PHE   A 1 235 ? -7.92009  0.35658   4.24220   1.000 19.23476 ?  215 PHE   A CE1 1 
ATOM   1497 C CE2 . PHE   A 1 235 ? -10.28033 0.10752   3.98445   1.000 19.68667 ?  215 PHE   A CE2 1 
ATOM   1498 C CZ  . PHE   A 1 235 ? -9.05989  -0.41219  4.36229   1.000 21.32400 ?  215 PHE   A CZ  1 
ATOM   1499 N N   . THR   A 1 236 ? -6.53069  4.29079   1.58705   1.000 22.79315 ?  216 THR   A N   1 
ATOM   1500 C CA  . THR   A 1 236 ? -5.09076  4.06924   1.58817   1.000 24.85775 ?  216 THR   A CA  1 
ATOM   1501 C C   . THR   A 1 236 ? -4.54189  4.52921   2.92822   1.000 22.10249 ?  216 THR   A C   1 
ATOM   1502 O O   . THR   A 1 236 ? -4.60599  5.72003   3.25084   1.000 24.99171 ?  216 THR   A O   1 
ATOM   1503 C CB  . THR   A 1 236 ? -4.40908  4.81815   0.43986   1.000 27.74151 ?  216 THR   A CB  1 
ATOM   1504 O OG1 . THR   A 1 236 ? -4.80071  4.23744   -0.81068  1.000 29.59730 ?  216 THR   A OG1 1 
ATOM   1505 C CG2 . THR   A 1 236 ? -2.89559  4.74087   0.57847   1.000 29.45936 ?  216 THR   A CG2 1 
ATOM   1506 N N   . VAL   A 1 237 ? -4.01450  3.58725   3.70914   1.000 21.30222 ?  217 VAL   A N   1 
ATOM   1507 C CA  . VAL   A 1 237 ? -3.48937  3.86799   5.03607   1.000 22.22231 ?  217 VAL   A CA  1 
ATOM   1508 C C   . VAL   A 1 237 ? -2.11364  3.22719   5.16479   1.000 22.24441 ?  217 VAL   A C   1 
ATOM   1509 O O   . VAL   A 1 237 ? -1.66770  2.47196   4.30031   1.000 24.66662 ?  217 VAL   A O   1 
ATOM   1510 C CB  . VAL   A 1 237 ? -4.42656  3.36824   6.15490   1.000 19.84863 ?  217 VAL   A CB  1 
ATOM   1511 C CG1 . VAL   A 1 237 ? -5.76849  4.07386   6.08218   1.000 24.64553 ?  217 VAL   A CG1 1 
ATOM   1512 C CG2 . VAL   A 1 237 ? -4.61612  1.86616   6.05220   1.000 23.25150 ?  217 VAL   A CG2 1 
ATOM   1513 N N   . LEU   A 1 238 ? -1.44062  3.54786   6.26645   1.000 27.17722 ?  218 LEU   A N   1 
ATOM   1514 C CA  . LEU   A 1 238 ? -0.14443  2.95138   6.55557   1.000 22.19463 ?  218 LEU   A CA  1 
ATOM   1515 C C   . LEU   A 1 238 ? -0.30388  1.47174   6.87371   1.000 23.29141 ?  218 LEU   A C   1 
ATOM   1516 O O   . LEU   A 1 238 ? -1.18672  1.08200   7.64366   1.000 23.16906 ?  218 LEU   A O   1 
ATOM   1517 C CB  . LEU   A 1 238 ? 0.52096   3.66635   7.72863   1.000 24.90340 ?  218 LEU   A CB  1 
ATOM   1518 C CG  . LEU   A 1 238 ? 1.49893   4.79210   7.40541   1.000 33.69275 ?  218 LEU   A CG  1 
ATOM   1519 C CD1 . LEU   A 1 238 ? 2.17635   5.26471   8.67941   1.000 25.54287 ?  218 LEU   A CD1 1 
ATOM   1520 C CD2 . LEU   A 1 238 ? 2.52727   4.32874   6.38711   1.000 26.73717 ?  218 LEU   A CD2 1 
ATOM   1521 N N   . GLN   A 1 239 ? 0.55198   0.64872   6.27915   1.000 20.51984 ?  219 GLN   A N   1 
ATOM   1522 C CA  . GLN   A 1 239 ? 0.59699   -0.77775  6.56496   1.000 22.04325 ?  219 GLN   A CA  1 
ATOM   1523 C C   . GLN   A 1 239 ? 1.73864   -1.04348  7.53752   1.000 21.66125 ?  219 GLN   A C   1 
ATOM   1524 O O   . GLN   A 1 239 ? 2.90369   -0.77884  7.22049   1.000 20.99658 ?  219 GLN   A O   1 
ATOM   1525 C CB  . GLN   A 1 239 ? 0.77827   -1.59137  5.28422   1.000 20.25924 ?  219 GLN   A CB  1 
ATOM   1526 C CG  . GLN   A 1 239 ? 0.98707   -3.07520  5.53126   1.000 17.88551 ?  219 GLN   A CG  1 
ATOM   1527 C CD  . GLN   A 1 239 ? -0.30924  -3.81099  5.80659   1.000 20.84346 ?  219 GLN   A CD  1 
ATOM   1528 O OE1 . GLN   A 1 239 ? -1.07138  -4.11345  4.88935   1.000 18.84186 ?  219 GLN   A OE1 1 
ATOM   1529 N NE2 . GLN   A 1 239 ? -0.56533  -4.10457  7.07711   1.000 22.43495 ?  219 GLN   A NE2 1 
ATOM   1530 N N   . ASP   A 1 240 ? 1.40365   -1.55726  8.71602   1.000 17.28549 ?  220 ASP   A N   1 
ATOM   1531 C CA  . ASP   A 1 240 ? 2.38213   -1.84602  9.75114   1.000 16.76602 ?  220 ASP   A CA  1 
ATOM   1532 C C   . ASP   A 1 240 ? 2.31281   -3.31743  10.13673  1.000 22.35247 ?  220 ASP   A C   1 
ATOM   1533 O O   . ASP   A 1 240 ? 1.40806   -4.05189  9.73263   1.000 22.55208 ?  220 ASP   A O   1 
ATOM   1534 C CB  . ASP   A 1 240 ? 2.16441   -0.95496  10.97939  1.000 16.47459 ?  220 ASP   A CB  1 
ATOM   1535 C CG  . ASP   A 1 240 ? 2.84696   0.38933   10.84650  1.000 24.66400 ?  220 ASP   A CG  1 
ATOM   1536 O OD1 . ASP   A 1 240 ? 4.09620   0.42505   10.84838  1.000 19.70540 ?  220 ASP   A OD1 1 
ATOM   1537 O OD2 . ASP   A 1 240 ? 2.13385   1.40847   10.73127  1.000 22.99631 ?  220 ASP   A OD2 1 
ATOM   1538 N N   . HIS   A 1 241 ? 3.29401   -3.74136  10.92585  1.000 23.61360 ?  221 HIS   A N   1 
ATOM   1539 C CA  . HIS   A 1 241 ? 3.45226   -5.13083  11.32282  1.000 22.99958 ?  221 HIS   A CA  1 
ATOM   1540 C C   . HIS   A 1 241 ? 3.05594   -5.31676  12.78110  1.000 22.16140 ?  221 HIS   A C   1 
ATOM   1541 O O   . HIS   A 1 241 ? 3.14945   -4.39146  13.59330  1.000 23.80841 ?  221 HIS   A O   1 
ATOM   1542 C CB  . HIS   A 1 241 ? 4.90117   -5.59201  11.11940  1.000 17.81076 ?  221 HIS   A CB  1 
ATOM   1543 C CG  . HIS   A 1 241 ? 5.06232   -7.07792  11.01299  1.000 26.11671 ?  221 HIS   A CG  1 
ATOM   1544 N ND1 . HIS   A 1 241 ? 5.08448   -7.90550  12.11529  1.000 20.91183 ?  221 HIS   A ND1 1 
ATOM   1545 C CD2 . HIS   A 1 241 ? 5.22732   -7.88272  9.93625   1.000 24.12784 ?  221 HIS   A CD2 1 
ATOM   1546 C CE1 . HIS   A 1 241 ? 5.24675   -9.15631  11.72186  1.000 24.78855 ?  221 HIS   A CE1 1 
ATOM   1547 N NE2 . HIS   A 1 241 ? 5.33663   -9.16991  10.40412  1.000 21.75387 ?  221 HIS   A NE2 1 
ATOM   1548 N N   . ALA   A 1 242 ? 2.59917   -6.52414  13.10033  1.000 20.76267 ?  222 ALA   A N   1 
ATOM   1549 C CA  . ALA   A 1 242 ? 2.45041   -6.91774  14.49234  1.000 25.10421 ?  222 ALA   A CA  1 
ATOM   1550 C C   . ALA   A 1 242 ? 3.82303   -6.98518  15.14909  1.000 21.21064 ?  222 ALA   A C   1 
ATOM   1551 O O   . ALA   A 1 242 ? 4.80246   -7.41608  14.53419  1.000 20.58300 ?  222 ALA   A O   1 
ATOM   1552 C CB  . ALA   A 1 242 ? 1.74169   -8.26756  14.59572  1.000 19.11460 ?  222 ALA   A CB  1 
ATOM   1553 N N   . VAL   A 1 243 ? 3.89624   -6.54782  16.40319  1.000 23.34992 ?  223 VAL   A N   1 
ATOM   1554 C CA  . VAL   A 1 243 ? 5.17003   -6.43198  17.10417  1.000 27.48075 ?  223 VAL   A CA  1 
ATOM   1555 C C   . VAL   A 1 243 ? 5.29288   -7.37767  18.28947  1.000 30.48369 ?  223 VAL   A C   1 
ATOM   1556 O O   . VAL   A 1 243 ? 6.39703   -7.50990  18.83823  1.000 22.98437 ?  223 VAL   A O   1 
ATOM   1557 C CB  . VAL   A 1 243 ? 5.42810   -4.97929  17.56066  1.000 24.09498 ?  223 VAL   A CB  1 
ATOM   1558 C CG1 . VAL   A 1 243 ? 5.46547   -4.04492  16.36000  1.000 22.66098 ?  223 VAL   A CG1 1 
ATOM   1559 C CG2 . VAL   A 1 243 ? 4.36313   -4.53998  18.54330  1.000 21.52307 ?  223 VAL   A CG2 1 
ATOM   1560 N N   . VAL   A 1 244 ? 4.21909   -8.04861  18.69956  1.000 25.33006 ?  224 VAL   A N   1 
ATOM   1561 C CA  . VAL   A 1 244 ? 4.24614   -8.94190  19.84735  1.000 26.61889 ?  224 VAL   A CA  1 
ATOM   1562 C C   . VAL   A 1 244 ? 4.22646   -10.40744 19.42778  1.000 31.45042 ?  224 VAL   A C   1 
ATOM   1563 O O   . VAL   A 1 244 ? 5.00834   -11.21130 19.94185  1.000 33.41050 ?  224 VAL   A O   1 
ATOM   1564 C CB  . VAL   A 1 244 ? 3.08072   -8.63007  20.81222  1.000 25.12034 ?  224 VAL   A CB  1 
ATOM   1565 C CG1 . VAL   A 1 244 ? 2.97186   -9.70844  21.87946  1.000 30.03337 ?  224 VAL   A CG1 1 
ATOM   1566 C CG2 . VAL   A 1 244 ? 3.27257   -7.26777  21.44969  1.000 21.01644 ?  224 VAL   A CG2 1 
ATOM   1567 N N   . SER   A 1 245 ? 3.34744   -10.77704 18.49835  1.000 34.97103 ?  225 SER   A N   1 
ATOM   1568 C CA  . SER   A 1 245 ? 3.18616   -12.18192 18.15460  1.000 35.65142 ?  225 SER   A CA  1 
ATOM   1569 C C   . SER   A 1 245 ? 2.65706   -12.31757 16.73471  1.000 37.81360 ?  225 SER   A C   1 
ATOM   1570 O O   . SER   A 1 245 ? 1.79266   -11.54642 16.31090  1.000 29.21718 ?  225 SER   A O   1 
ATOM   1571 C CB  . SER   A 1 245 ? 2.23663   -12.88143 19.13538  1.000 30.10142 ?  225 SER   A CB  1 
ATOM   1572 O OG  . SER   A 1 245 ? 0.97798   -12.23035 19.17436  1.000 42.59447 ?  225 SER   A OG  1 
ATOM   1573 N N   . GLY   A 1 246 ? 3.18442   -13.29971 16.01316  1.000 34.65429 ?  226 GLY   A N   1 
ATOM   1574 C CA  . GLY   A 1 246 ? 2.61504   -13.73283 14.75696  1.000 32.81635 ?  226 GLY   A CA  1 
ATOM   1575 C C   . GLY   A 1 246 ? 3.29085   -13.10579 13.54820  1.000 28.85261 ?  226 GLY   A C   1 
ATOM   1576 O O   . GLY   A 1 246 ? 3.86203   -12.01412 13.60422  1.000 33.77310 ?  226 GLY   A O   1 
ATOM   1577 N N   . GLU   A 1 247 ? 3.22201   -13.82818 12.43036  1.000 24.65703 ?  227 GLU   A N   1 
ATOM   1578 C CA  . GLU   A 1 247 ? 3.59298   -13.27962 11.12637  1.000 27.50888 ?  227 GLU   A CA  1 
ATOM   1579 C C   . GLU   A 1 247 ? 2.34203   -12.70305 10.46445  1.000 23.04255 ?  227 GLU   A C   1 
ATOM   1580 O O   . GLU   A 1 247 ? 1.80638   -13.22341 9.48418   1.000 22.99847 ?  227 GLU   A O   1 
ATOM   1581 C CB  . GLU   A 1 247 ? 4.25106   -14.34439 10.25875  1.000 28.05247 ?  227 GLU   A CB  1 
ATOM   1582 C CG  . GLU   A 1 247 ? 5.56387   -14.87435 10.79893  1.000 34.04842 ?  227 GLU   A CG  1 
ATOM   1583 C CD  . GLU   A 1 247 ? 6.48316   -15.35763 9.69647   1.000 33.85594 ?  227 GLU   A CD  1 
ATOM   1584 O OE1 . GLU   A 1 247 ? 5.98424   -15.98412 8.73776   1.000 26.38344 ?  227 GLU   A OE1 1 
ATOM   1585 O OE2 . GLU   A 1 247 ? 7.70378   -15.10637 9.78667   1.000 37.35742 ?  227 GLU   A OE2 1 
ATOM   1586 N N   . SER   A 1 248 ? 1.87152   -11.60424 11.04376  1.000 24.43144 ?  228 SER   A N   1 
ATOM   1587 C CA  . SER   A 1 248 ? 0.70747   -10.89381 10.54606  1.000 26.15048 ?  228 SER   A CA  1 
ATOM   1588 C C   . SER   A 1 248 ? 1.00125   -9.40287  10.51893  1.000 23.86173 ?  228 SER   A C   1 
ATOM   1589 O O   . SER   A 1 248 ? 1.84331   -8.90266  11.26938  1.000 20.45048 ?  228 SER   A O   1 
ATOM   1590 C CB  . SER   A 1 248 ? -0.53633  -11.16580 11.40636  1.000 25.23016 ?  228 SER   A CB  1 
ATOM   1591 O OG  . SER   A 1 248 ? -0.28644  -10.87925 12.77172  1.000 25.81881 ?  228 SER   A OG  1 
ATOM   1592 N N   . MET   A 1 249 ? 0.30256   -8.70184  9.63404   1.000 21.98917 ?  229 MET   A N   1 
ATOM   1593 C CA  . MET   A 1 249 ? 0.38964   -7.25602  9.52668   1.000 20.28359 ?  229 MET   A CA  1 
ATOM   1594 C C   . MET   A 1 249 ? -1.01364  -6.68064  9.61852   1.000 22.64879 ?  229 MET   A C   1 
ATOM   1595 O O   . MET   A 1 249 ? -1.98688  -7.31931  9.20878   1.000 22.64594 ?  229 MET   A O   1 
ATOM   1596 C CB  . MET   A 1 249 ? 1.04977   -6.82828  8.21083   1.000 20.91119 ?  229 MET   A CB  1 
ATOM   1597 C CG  . MET   A 1 249 ? 0.70516   -7.72291  7.03110   1.000 28.05815 ?  229 MET   A CG  1 
ATOM   1598 S SD  . MET   A 1 249 ? 1.56293   -7.26008  5.51444   1.000 31.61168 ?  229 MET   A SD  1 
ATOM   1599 C CE  . MET   A 1 249 ? 1.11885   -8.62996  4.45016   1.000 32.28537 ?  229 MET   A CE  1 
ATOM   1600 N N   . TYR   A 1 250 ? -1.11840  -5.47289  10.16727  1.000 22.40868 ?  230 TYR   A N   1 
ATOM   1601 C CA  . TYR   A 1 250 ? -2.41268  -4.81999  10.27944  1.000 21.49754 ?  230 TYR   A CA  1 
ATOM   1602 C C   . TYR   A 1 250 ? -2.29508  -3.35234  9.89743   1.000 21.89581 ?  230 TYR   A C   1 
ATOM   1603 O O   . TYR   A 1 250 ? -1.22671  -2.74355  10.00369  1.000 25.61741 ?  230 TYR   A O   1 
ATOM   1604 C CB  . TYR   A 1 250 ? -3.01472  -4.95738  11.69024  1.000 21.96336 ?  230 TYR   A CB  1 
ATOM   1605 C CG  . TYR   A 1 250 ? -2.05122  -4.77106  12.84464  1.000 18.87381 ?  230 TYR   A CG  1 
ATOM   1606 C CD1 . TYR   A 1 250 ? -1.40781  -3.55737  13.05484  1.000 20.28174 ?  230 TYR   A CD1 1 
ATOM   1607 C CD2 . TYR   A 1 250 ? -1.81113  -5.80203  13.74398  1.000 22.38856 ?  230 TYR   A CD2 1 
ATOM   1608 C CE1 . TYR   A 1 250 ? -0.53910  -3.38259  14.11699  1.000 21.58615 ?  230 TYR   A CE1 1 
ATOM   1609 C CE2 . TYR   A 1 250 ? -0.94517  -5.63679  14.80925  1.000 24.20953 ?  230 TYR   A CE2 1 
ATOM   1610 C CZ  . TYR   A 1 250 ? -0.31193  -4.42599  14.99126  1.000 28.54947 ?  230 TYR   A CZ  1 
ATOM   1611 O OH  . TYR   A 1 250 ? 0.55045   -4.26029  16.05143  1.000 21.80661 ?  230 TYR   A OH  1 
ATOM   1612 N N   . ALA   A 1 251 ? -3.41561  -2.79725  9.44239   1.000 18.11043 ?  231 ALA   A N   1 
ATOM   1613 C CA  . ALA   A 1 251 ? -3.51558  -1.40123  9.04462   1.000 24.28579 ?  231 ALA   A CA  1 
ATOM   1614 C C   . ALA   A 1 251 ? -4.78679  -0.81815  9.63991   1.000 17.68330 ?  231 ALA   A C   1 
ATOM   1615 O O   . ALA   A 1 251 ? -5.85371  -1.43491  9.55544   1.000 17.02625 ?  231 ALA   A O   1 
ATOM   1616 C CB  . ALA   A 1 251 ? -3.52323  -1.25661  7.51953   1.000 16.71041 ?  231 ALA   A CB  1 
ATOM   1617 N N   . TRP   A 1 252 ? -4.66924  0.36071   10.24586  1.000 18.86388 ?  232 TRP   A N   1 
ATOM   1618 C CA  . TRP   A 1 252 ? -5.81380  1.02336   10.86258  1.000 17.89571 ?  232 TRP   A CA  1 
ATOM   1619 C C   . TRP   A 1 252 ? -6.73818  1.54319   9.76823   1.000 20.79625 ?  232 TRP   A C   1 
ATOM   1620 O O   . TRP   A 1 252 ? -6.39858  2.49487   9.05731   1.000 23.90933 ?  232 TRP   A O   1 
ATOM   1621 C CB  . TRP   A 1 252 ? -5.34098  2.15909   11.76409  1.000 17.97547 ?  232 TRP   A CB  1 
ATOM   1622 C CG  . TRP   A 1 252 ? -5.01281  1.74124   13.17085  1.000 20.43722 ?  232 TRP   A CG  1 
ATOM   1623 C CD1 . TRP   A 1 252 ? -5.80116  1.88616   14.27578  1.000 19.04067 ?  232 TRP   A CD1 1 
ATOM   1624 C CD2 . TRP   A 1 252 ? -3.79939  1.12534   13.62286  1.000 18.73234 ?  232 TRP   A CD2 1 
ATOM   1625 N NE1 . TRP   A 1 252 ? -5.15656  1.39449   15.38565  1.000 20.48946 ?  232 TRP   A NE1 1 
ATOM   1626 C CE2 . TRP   A 1 252 ? -3.92528  0.92364   15.01205  1.000 20.16593 ?  232 TRP   A CE2 1 
ATOM   1627 C CE3 . TRP   A 1 252 ? -2.61889  0.72624   12.98746  1.000 17.85051 ?  232 TRP   A CE3 1 
ATOM   1628 C CZ2 . TRP   A 1 252 ? -2.91761  0.33567   15.77567  1.000 20.20750 ?  232 TRP   A CZ2 1 
ATOM   1629 C CZ3 . TRP   A 1 252 ? -1.61960  0.14478   13.74712  1.000 18.48007 ?  232 TRP   A CZ3 1 
ATOM   1630 C CH2 . TRP   A 1 252 ? -1.77551  -0.04574  15.12572  1.000 18.04366 ?  232 TRP   A CH2 1 
ATOM   1631 N N   . ALA   A 1 253 ? -7.90567  0.92040   9.62937   1.000 20.91402 ?  233 ALA   A N   1 
ATOM   1632 C CA  . ALA   A 1 253 ? -8.83854  1.28691   8.57766   1.000 20.93464 ?  233 ALA   A CA  1 
ATOM   1633 C C   . ALA   A 1 253 ? -9.71781  2.45833   9.01620   1.000 17.46339 ?  233 ALA   A C   1 
ATOM   1634 O O   . ALA   A 1 253 ? -9.99750  2.62454   10.20662  1.000 16.40972 ?  233 ALA   A O   1 
ATOM   1635 C CB  . ALA   A 1 253 ? -9.70879  0.09215   8.20259   1.000 17.24973 ?  233 ALA   A CB  1 
ATOM   1636 N N   . PRO   A 1 254 ? -10.15952 3.29201   8.06901   1.000 20.76372 ?  234 PRO   A N   1 
ATOM   1637 C CA  . PRO   A 1 254 ? -10.96003 4.48922   8.41110   1.000 16.50682 ?  234 PRO   A CA  1 
ATOM   1638 C C   . PRO   A 1 254 ? -12.44560 4.20523   8.62959   1.000 22.08032 ?  234 PRO   A C   1 
ATOM   1639 O O   . PRO   A 1 254 ? -13.31452 4.51490   7.81131   1.000 21.50847 ?  234 PRO   A O   1 
ATOM   1640 C CB  . PRO   A 1 254 ? -10.72768 5.39615   7.20105   1.000 16.00381 ?  234 PRO   A CB  1 
ATOM   1641 C CG  . PRO   A 1 254 ? -10.57458 4.43454   6.06876   1.000 26.59210 ?  234 PRO   A CG  1 
ATOM   1642 C CD  . PRO   A 1 254 ? -9.82370  3.25133   6.63380   1.000 19.41517 ?  234 PRO   A CD  1 
ATOM   1643 N N   . LEU   A 1 255 ? -12.74825 3.60374   9.77837   1.000 18.94782 ?  235 LEU   A N   1 
ATOM   1644 C CA  . LEU   A 1 255 ? -14.12062 3.34543   10.19794  1.000 20.63915 ?  235 LEU   A CA  1 
ATOM   1645 C C   . LEU   A 1 255 ? -14.10101 2.90409   11.65294  1.000 18.86082 ?  235 LEU   A C   1 
ATOM   1646 O O   . LEU   A 1 255 ? -13.05534 2.52722   12.19076  1.000 18.30497 ?  235 LEU   A O   1 
ATOM   1647 C CB  . LEU   A 1 255 ? -14.79867 2.27597   9.33229   1.000 21.46138 ?  235 LEU   A CB  1 
ATOM   1648 C CG  . LEU   A 1 255 ? -14.47208 0.81523   9.65669   1.000 26.02519 ?  235 LEU   A CG  1 
ATOM   1649 C CD1 . LEU   A 1 255 ? -15.52730 -0.10667  9.07151   1.000 23.75881 ?  235 LEU   A CD1 1 
ATOM   1650 C CD2 . LEU   A 1 255 ? -13.09129 0.42981   9.15882   1.000 21.06471 ?  235 LEU   A CD2 1 
ATOM   1651 N N   . VAL   A 1 256 ? -15.27320 2.95888   12.28261  1.000 19.69054 ?  236 VAL   A N   1 
ATOM   1652 C CA  . VAL   A 1 256 ? -15.48893 2.41121   13.62018  1.000 21.60717 ?  236 VAL   A CA  1 
ATOM   1653 C C   . VAL   A 1 256 ? -16.68126 1.46918   13.51438  1.000 18.32910 ?  236 VAL   A C   1 
ATOM   1654 O O   . VAL   A 1 256 ? -17.83545 1.91193   13.52148  1.000 20.52758 ?  236 VAL   A O   1 
ATOM   1655 C CB  . VAL   A 1 256 ? -15.73271 3.49385   14.67651  1.000 19.11184 ?  236 VAL   A CB  1 
ATOM   1656 C CG1 . VAL   A 1 256 ? -15.79772 2.87070   16.06116  1.000 19.72315 ?  236 VAL   A CG1 1 
ATOM   1657 C CG2 . VAL   A 1 256 ? -14.64072 4.54640   14.61913  1.000 21.80218 ?  236 VAL   A CG2 1 
ATOM   1658 N N   . SER   A 1 257 ? -16.41153 0.17249   13.41468  1.000 17.14419 ?  237 SER   A N   1 
ATOM   1659 C CA  . SER   A 1 257 ? -17.46413 -0.82306  13.28573  1.000 21.42675 ?  237 SER   A CA  1 
ATOM   1660 C C   . SER   A 1 257 ? -17.83617 -1.36583  14.65894  1.000 24.82622 ?  237 SER   A C   1 
ATOM   1661 O O   . SER   A 1 257 ? -16.96194 -1.76064  15.43789  1.000 22.40575 ?  237 SER   A O   1 
ATOM   1662 C CB  . SER   A 1 257 ? -17.02041 -1.96125  12.36755  1.000 19.89873 ?  237 SER   A CB  1 
ATOM   1663 O OG  . SER   A 1 257 ? -17.83966 -3.10209  12.54893  1.000 18.84400 ?  237 SER   A OG  1 
ATOM   1664 N N   . VAL   A 1 258 ? -19.13390 -1.37301  14.95452  1.000 20.47047 ?  238 VAL   A N   1 
ATOM   1665 C CA  . VAL   A 1 258 ? -19.63898 -1.96951  16.18482  1.000 18.52559 ?  238 VAL   A CA  1 
ATOM   1666 C C   . VAL   A 1 258 ? -20.47523 -3.18560  15.81375  1.000 18.60551 ?  238 VAL   A C   1 
ATOM   1667 O O   . VAL   A 1 258 ? -21.37416 -3.59042  16.55886  1.000 23.32388 ?  238 VAL   A O   1 
ATOM   1668 C CB  . VAL   A 1 258 ? -20.45086 -0.95735  17.01374  1.000 19.66016 ?  238 VAL   A CB  1 
ATOM   1669 C CG1 . VAL   A 1 258 ? -19.53428 0.10935   17.59242  1.000 23.72092 ?  238 VAL   A CG1 1 
ATOM   1670 C CG2 . VAL   A 1 258 ? -21.53356 -0.31994  16.16033  1.000 20.91166 ?  238 VAL   A CG2 1 
ATOM   1671 N N   . ALA   A 1 259 ? -20.17928 -3.77380  14.65843  1.000 22.14269 ?  239 ALA   A N   1 
ATOM   1672 C CA  . ALA   A 1 259 ? -20.92259 -4.93013  14.19240  1.000 17.07722 ?  239 ALA   A CA  1 
ATOM   1673 C C   . ALA   A 1 259 ? -20.62791 -6.14914  15.06482  1.000 23.55916 ?  239 ALA   A C   1 
ATOM   1674 O O   . ALA   A 1 259 ? -19.55323 -6.25171  15.66233  1.000 21.04508 ?  239 ALA   A O   1 
ATOM   1675 C CB  . ALA   A 1 259 ? -20.56455 -5.24326  12.74321  1.000 20.19342 ?  239 ALA   A CB  1 
ATOM   1676 N N   . PRO   A 1 260 ? -21.56951 -7.08353  15.16129  1.000 24.48219 ?  240 PRO   A N   1 
ATOM   1677 C CA  . PRO   A 1 260 ? -21.26196 -8.37093  15.78941  1.000 24.30567 ?  240 PRO   A CA  1 
ATOM   1678 C C   . PRO   A 1 260 ? -20.27160 -9.15864  14.94613  1.000 26.13942 ?  240 PRO   A C   1 
ATOM   1679 O O   . PRO   A 1 260 ? -20.15003 -8.96690  13.73413  1.000 25.16928 ?  240 PRO   A O   1 
ATOM   1680 C CB  . PRO   A 1 260 ? -22.62078 -9.07728  15.85349  1.000 29.06868 ?  240 PRO   A CB  1 
ATOM   1681 C CG  . PRO   A 1 260 ? -23.45753 -8.39664  14.82014  1.000 32.10253 ?  240 PRO   A CG  1 
ATOM   1682 C CD  . PRO   A 1 260 ? -22.98558 -6.97721  14.77091  1.000 24.65894 ?  240 PRO   A CD  1 
ATOM   1683 N N   . THR   A 1 261 ? -19.54956 -10.05746 15.61161  1.000 24.18385 ?  241 THR   A N   1 
ATOM   1684 C CA  . THR   A 1 261 ? -18.55207 -10.91085 14.96461  1.000 28.44774 ?  241 THR   A CA  1 
ATOM   1685 C C   . THR   A 1 261 ? -18.79684 -12.36156 15.36200  1.000 26.56429 ?  241 THR   A C   1 
ATOM   1686 O O   . THR   A 1 261 ? -18.02883 -12.94728 16.13454  1.000 26.01611 ?  241 THR   A O   1 
ATOM   1687 C CB  . THR   A 1 261 ? -17.13254 -10.47722 15.33387  1.000 28.73480 ?  241 THR   A CB  1 
ATOM   1688 O OG1 . THR   A 1 261 ? -16.98196 -10.48817 16.75894  1.000 23.49924 ?  241 THR   A OG1 1 
ATOM   1689 C CG2 . THR   A 1 261 ? -16.84269 -9.07700  14.80553  1.000 28.52751 ?  241 THR   A CG2 1 
ATOM   1690 N N   . PRO   A 1 262 ? -19.86184 -12.97845 14.84076  1.000 29.98797 ?  242 PRO   A N   1 
ATOM   1691 C CA  . PRO   A 1 262 ? -20.17418 -14.35428 15.25977  1.000 32.04691 ?  242 PRO   A CA  1 
ATOM   1692 C C   . PRO   A 1 262 ? -19.21155 -15.39724 14.71600  1.000 31.43075 ?  242 PRO   A C   1 
ATOM   1693 O O   . PRO   A 1 262 ? -19.00842 -16.42693 15.37049  1.000 35.47936 ?  242 PRO   A O   1 
ATOM   1694 C CB  . PRO   A 1 262 ? -21.59647 -14.57079 14.72399  1.000 27.40635 ?  242 PRO   A CB  1 
ATOM   1695 C CG  . PRO   A 1 262 ? -21.72850 -13.60912 13.59712  1.000 30.47478 ?  242 PRO   A CG  1 
ATOM   1696 C CD  . PRO   A 1 262 ? -20.90118 -12.41509 13.96098  1.000 31.72909 ?  242 PRO   A CD  1 
ATOM   1697 N N   . VAL   A 1 263 ? -18.61570 -15.17381 13.54801  1.000 31.61727 ?  243 VAL   A N   1 
ATOM   1698 C CA  . VAL   A 1 263 ? -17.76782 -16.16294 12.88987  1.000 26.14256 ?  243 VAL   A CA  1 
ATOM   1699 C C   . VAL   A 1 263 ? -16.31501 -15.76042 13.11356  1.000 28.47024 ?  243 VAL   A C   1 
ATOM   1700 O O   . VAL   A 1 263 ? -15.84516 -14.75617 12.56337  1.000 28.01481 ?  243 VAL   A O   1 
ATOM   1701 C CB  . VAL   A 1 263 ? -18.09112 -16.28282 11.39421  1.000 22.21563 ?  243 VAL   A CB  1 
ATOM   1702 C CG1 . VAL   A 1 263 ? -17.03619 -17.12094 10.68303  1.000 20.66812 ?  243 VAL   A CG1 1 
ATOM   1703 C CG2 . VAL   A 1 263 ? -19.48025 -16.87676 11.19569  1.000 29.28202 ?  243 VAL   A CG2 1 
ATOM   1704 N N   . ARG   A 1 264 ? -15.60220 -16.54549 13.91961  1.000 27.44150 ?  244 ARG   A N   1 
ATOM   1705 C CA  . ARG   A 1 264 ? -14.20197 -16.30341 14.23194  1.000 28.39852 ?  244 ARG   A CA  1 
ATOM   1706 C C   . ARG   A 1 264 ? -13.39514 -17.56298 13.94782  1.000 28.66789 ?  244 ARG   A C   1 
ATOM   1707 O O   . ARG   A 1 264 ? -13.93800 -18.66840 13.88158  1.000 28.86029 ?  244 ARG   A O   1 
ATOM   1708 C CB  . ARG   A 1 264 ? -14.01886 -15.87820 15.69513  1.000 27.38613 ?  244 ARG   A CB  1 
ATOM   1709 C CG  . ARG   A 1 264 ? -14.73671 -14.59113 16.06341  1.000 29.78779 ?  244 ARG   A CG  1 
ATOM   1710 C CD  . ARG   A 1 264 ? -14.48620 -14.21957 17.51751  1.000 29.06927 ?  244 ARG   A CD  1 
ATOM   1711 N NE  . ARG   A 1 264 ? -14.70400 -12.80130 17.77856  1.000 35.14337 ?  244 ARG   A NE  1 
ATOM   1712 C CZ  . ARG   A 1 264 ? -13.74332 -11.93290 18.06597  1.000 33.98808 ?  244 ARG   A CZ  1 
ATOM   1713 N NH1 . ARG   A 1 264 ? -12.47528 -12.30331 18.14159  1.000 28.00625 ?  244 ARG   A NH1 1 
ATOM   1714 N NH2 . ARG   A 1 264 ? -14.06393 -10.66168 18.29036  1.000 40.73002 ?  244 ARG   A NH2 1 
ATOM   1715 N N   . GLU   A 1 265 ? -12.08374 -17.38650 13.78426  1.000 26.86971 ?  245 GLU   A N   1 
ATOM   1716 C CA  . GLU   A 1 265 ? -11.19320 -18.49254 13.45485  1.000 32.43762 ?  245 GLU   A CA  1 
ATOM   1717 C C   . GLU   A 1 265 ? -9.90921  -18.37346 14.26194  1.000 32.37504 ?  245 GLU   A C   1 
ATOM   1718 O O   . GLU   A 1 265 ? -9.35021  -17.27907 14.38425  1.000 28.15640 ?  245 GLU   A O   1 
ATOM   1719 C CB  . GLU   A 1 265 ? -10.88768 -18.51849 11.95142  1.000 33.37696 ?  245 GLU   A CB  1 
ATOM   1720 C CG  . GLU   A 1 265 ? -9.49458  -19.00577 11.59346  1.000 33.17147 ?  245 GLU   A CG  1 
ATOM   1721 C CD  . GLU   A 1 265 ? -9.21494  -18.90364 10.10890  1.000 36.66412 ?  245 GLU   A CD  1 
ATOM   1722 O OE1 . GLU   A 1 265 ? -9.69156  -19.77344 9.34934   1.000 30.30444 ?  245 GLU   A OE1 1 
ATOM   1723 O OE2 . GLU   A 1 265 ? -8.52805  -17.94381 9.69965   1.000 36.35855 ?  245 GLU   A OE2 1 
ATOM   1724 N N   . ARG   A 1 266 ? -9.45434  -19.49911 14.81482  1.000 32.32363 ?  246 ARG   A N   1 
ATOM   1725 C CA  . ARG   A 1 266 ? -8.21262  -19.52579 15.57867  1.000 36.14818 ?  246 ARG   A CA  1 
ATOM   1726 C C   . ARG   A 1 266 ? -7.04987  -19.04593 14.71982  1.000 27.91401 ?  246 ARG   A C   1 
ATOM   1727 O O   . ARG   A 1 266 ? -6.89926  -19.46552 13.56855  1.000 31.13873 ?  246 ARG   A O   1 
ATOM   1728 C CB  . ARG   A 1 266 ? -7.94911  -20.94259 16.09671  1.000 34.88104 ?  246 ARG   A CB  1 
ATOM   1729 C CG  . ARG   A 1 266 ? -9.05158  -21.48579 16.99486  1.000 39.30350 ?  246 ARG   A CG  1 
ATOM   1730 C CD  . ARG   A 1 266 ? -8.89363  -22.97902 17.25976  1.000 41.54215 ?  246 ARG   A CD  1 
ATOM   1731 N NE  . ARG   A 1 266 ? -7.50241  -23.41789 17.25962  1.000 44.51455 ?  246 ARG   A NE  1 
ATOM   1732 C CZ  . ARG   A 1 266 ? -6.85486  -23.86229 18.32858  1.000 47.10964 ?  246 ARG   A CZ  1 
ATOM   1733 N NH1 . ARG   A 1 266 ? -7.44371  -23.94036 19.51074  1.000 46.41214 ?  246 ARG   A NH1 1 
ATOM   1734 N NH2 . ARG   A 1 266 ? -5.58633  -24.24446 18.20692  1.000 36.06246 ?  246 ARG   A NH2 1 
ATOM   1735 N N   . ILE   A 1 267 ? -6.23191  -18.15233 15.28554  1.000 29.51702 ?  247 ILE   A N   1 
ATOM   1736 C CA  . ILE   A 1 267 ? -5.16518  -17.52410 14.50648  1.000 31.18066 ?  247 ILE   A CA  1 
ATOM   1737 C C   . ILE   A 1 267 ? -4.16782  -18.57004 14.02715  1.000 30.12102 ?  247 ILE   A C   1 
ATOM   1738 O O   . ILE   A 1 267 ? -3.72665  -18.54888 12.87211  1.000 31.65422 ?  247 ILE   A O   1 
ATOM   1739 C CB  . ILE   A 1 267 ? -4.46019  -16.42411 15.32174  1.000 26.88639 ?  247 ILE   A CB  1 
ATOM   1740 C CG1 . ILE   A 1 267 ? -5.40208  -15.76508 16.32636  1.000 30.47065 ?  247 ILE   A CG1 1 
ATOM   1741 C CG2 . ILE   A 1 267 ? -3.87224  -15.37892 14.39767  1.000 29.88755 ?  247 ILE   A CG2 1 
ATOM   1742 C CD1 . ILE   A 1 267 ? -6.48994  -14.95202 15.69736  1.000 27.40882 ?  247 ILE   A CD1 1 
ATOM   1743 N N   . CYS   A 1 268 ? -3.79342  -19.49873 14.91193  1.000 29.97115 ?  248 CYS   A N   1 
ATOM   1744 C CA  . CYS   A 1 268 ? -2.77952  -20.48921 14.56460  1.000 31.37410 ?  248 CYS   A CA  1 
ATOM   1745 C C   . CYS   A 1 268 ? -3.20857  -21.34348 13.38105  1.000 34.02463 ?  248 CYS   A C   1 
ATOM   1746 O O   . CYS   A 1 268 ? -2.35859  -21.87433 12.65728  1.000 33.51105 ?  248 CYS   A O   1 
ATOM   1747 C CB  . CYS   A 1 268 ? -2.47109  -21.37111 15.77508  1.000 29.37077 ?  248 CYS   A CB  1 
ATOM   1748 S SG  . CYS   A 1 268 ? -3.89675  -22.25192 16.44727  1.000 32.35405 ?  248 CYS   A SG  1 
ATOM   1749 N N   . ASP   A 1 269 ? -4.51241  -21.47877 13.16165  1.000 29.30157 ?  249 ASP   A N   1 
ATOM   1750 C CA  . ASP   A 1 269 ? -5.03773  -22.23921 12.04065  1.000 29.17103 ?  249 ASP   A CA  1 
ATOM   1751 C C   . ASP   A 1 269 ? -5.40122  -21.35885 10.85356  1.000 37.63703 ?  249 ASP   A C   1 
ATOM   1752 O O   . ASP   A 1 269 ? -5.93264  -21.86925 9.86267   1.000 34.38287 ?  249 ASP   A O   1 
ATOM   1753 C CB  . ASP   A 1 269 ? -6.26212  -23.04042 12.48305  1.000 31.45612 ?  249 ASP   A CB  1 
ATOM   1754 C CG  . ASP   A 1 269 ? -5.95543  -23.99675 13.61736  1.000 35.16907 ?  249 ASP   A CG  1 
ATOM   1755 O OD1 . ASP   A 1 269 ? -4.82961  -24.53686 13.65900  1.000 41.71886 ?  249 ASP   A OD1 1 
ATOM   1756 O OD2 . ASP   A 1 269 ? -6.84323  -24.20679 14.46958  1.000 37.30182 ?  249 ASP   A OD2 1 
ATOM   1757 N N   . ALA   A 1 270 ? -5.13396  -20.05943 10.93110  1.000 33.74808 ?  250 ALA   A N   1 
ATOM   1758 C CA  . ALA   A 1 270 ? -5.48484  -19.15729 9.84215   1.000 26.44192 ?  250 ALA   A CA  1 
ATOM   1759 C C   . ALA   A 1 270 ? -4.59256  -19.42746 8.63690   1.000 32.79630 ?  250 ALA   A C   1 
ATOM   1760 O O   . ALA   A 1 270 ? -3.36463  -19.47532 8.77822   1.000 30.87797 ?  250 ALA   A O   1 
ATOM   1761 C CB  . ALA   A 1 270 ? -5.35074  -17.70133 10.28169  1.000 29.88380 ?  250 ALA   A CB  1 
ATOM   1762 N N   . PRO   A 1 271 ? -5.15996  -19.61013 7.44890   1.000 27.89433 ?  251 PRO   A N   1 
ATOM   1763 C CA  . PRO   A 1 271 ? -4.33324  -19.87801 6.26989   1.000 23.65612 ?  251 PRO   A CA  1 
ATOM   1764 C C   . PRO   A 1 271 ? -3.58006  -18.63521 5.82381   1.000 29.59443 ?  251 PRO   A C   1 
ATOM   1765 O O   . PRO   A 1 271 ? -3.89026  -17.50683 6.21226   1.000 23.24886 ?  251 PRO   A O   1 
ATOM   1766 C CB  . PRO   A 1 271 ? -5.35381  -20.31317 5.21404   1.000 30.21017 ?  251 PRO   A CB  1 
ATOM   1767 C CG  . PRO   A 1 271 ? -6.61932  -19.63408 5.62879   1.000 26.61424 ?  251 PRO   A CG  1 
ATOM   1768 C CD  . PRO   A 1 271 ? -6.59852  -19.59648 7.13145   1.000 26.26422 ?  251 PRO   A CD  1 
ATOM   1769 N N   . VAL   A 1 272 ? -2.56194  -18.86417 4.99231   1.000 26.77719 ?  252 VAL   A N   1 
ATOM   1770 C CA  . VAL   A 1 272 ? -1.84867  -17.75429 4.37600   1.000 34.58200 ?  252 VAL   A CA  1 
ATOM   1771 C C   . VAL   A 1 272 ? -2.80993  -16.98939 3.48019   1.000 30.92624 ?  252 VAL   A C   1 
ATOM   1772 O O   . VAL   A 1 272 ? -3.55015  -17.58199 2.68508   1.000 29.05628 ?  252 VAL   A O   1 
ATOM   1773 C CB  . VAL   A 1 272 ? -0.63140  -18.26751 3.59287   1.000 31.81904 ?  252 VAL   A CB  1 
ATOM   1774 C CG1 . VAL   A 1 272 ? 0.04907   -17.12336 2.85959   1.000 32.09109 ?  252 VAL   A CG1 1 
ATOM   1775 C CG2 . VAL   A 1 272 ? 0.34640   -18.96484 4.52668   1.000 24.71689 ?  252 VAL   A CG2 1 
ATOM   1776 N N   . GLY   A 1 273 ? -2.81144  -15.66560 3.61159   1.000 27.34024 ?  253 GLY   A N   1 
ATOM   1777 C CA  . GLY   A 1 273 ? -3.74066  -14.83352 2.88153   1.000 30.50499 ?  253 GLY   A CA  1 
ATOM   1778 C C   . GLY   A 1 273 ? -5.03819  -14.54914 3.60062   1.000 30.62391 ?  253 GLY   A C   1 
ATOM   1779 O O   . GLY   A 1 273 ? -5.89876  -13.85789 3.03943   1.000 30.55878 ?  253 GLY   A O   1 
ATOM   1780 N N   . ARG   A 1 274 ? -5.20879  -15.06209 4.81734   1.000 27.31578 ?  254 ARG   A N   1 
ATOM   1781 C CA  . ARG   A 1 274 ? -6.41583  -14.79588 5.58660   1.000 25.94581 ?  254 ARG   A CA  1 
ATOM   1782 C C   . ARG   A 1 274 ? -6.55888  -13.30612 5.86307   1.000 25.60817 ?  254 ARG   A C   1 
ATOM   1783 O O   . ARG   A 1 274 ? -5.62044  -12.65301 6.32824   1.000 19.81773 ?  254 ARG   A O   1 
ATOM   1784 C CB  . ARG   A 1 274 ? -6.38492  -15.57125 6.90459   1.000 23.08363 ?  254 ARG   A CB  1 
ATOM   1785 C CG  . ARG   A 1 274 ? -7.45015  -15.13854 7.90747   1.000 24.03159 ?  254 ARG   A CG  1 
ATOM   1786 C CD  . ARG   A 1 274 ? -8.85409  -15.38037 7.38200   1.000 23.17783 ?  254 ARG   A CD  1 
ATOM   1787 N NE  . ARG   A 1 274 ? -9.19111  -16.79815 7.37716   1.000 30.35602 ?  254 ARG   A NE  1 
ATOM   1788 C CZ  . ARG   A 1 274 ? -9.85854  -17.40813 6.40779   1.000 31.48856 ?  254 ARG   A CZ  1 
ATOM   1789 N NH1 . ARG   A 1 274 ? -10.27339 -16.75358 5.33538   1.000 30.08454 ?  254 ARG   A NH1 1 
ATOM   1790 N NH2 . ARG   A 1 274 ? -10.11740 -18.70765 6.51781   1.000 32.88770 ?  254 ARG   A NH2 1 
ATOM   1791 N N   . LEU   A 1 275 ? -7.73758  -12.77015 5.56634   1.000 24.55300 ?  255 LEU   A N   1 
ATOM   1792 C CA  . LEU   A 1 275 ? -8.09445  -11.40705 5.93073   1.000 28.04222 ?  255 LEU   A CA  1 
ATOM   1793 C C   . LEU   A 1 275 ? -8.97930  -11.45945 7.16802   1.000 25.88870 ?  255 LEU   A C   1 
ATOM   1794 O O   . LEU   A 1 275 ? -10.06990 -12.03910 7.13081   1.000 30.61591 ?  255 LEU   A O   1 
ATOM   1795 C CB  . LEU   A 1 275 ? -8.81412  -10.69335 4.78584   1.000 29.26619 ?  255 LEU   A CB  1 
ATOM   1796 C CG  . LEU   A 1 275 ? -8.09789  -10.59653 3.43714   1.000 28.25121 ?  255 LEU   A CG  1 
ATOM   1797 C CD1 . LEU   A 1 275 ? -8.98637  -9.91493  2.40466   1.000 33.21910 ?  255 LEU   A CD1 1 
ATOM   1798 C CD2 . LEU   A 1 275 ? -6.77662  -9.85603  3.57734   1.000 19.84697 ?  255 LEU   A CD2 1 
ATOM   1799 N N   . ARG   A 1 276 ? -8.50450  -10.87624 8.25957   1.000 20.12540 ?  256 ARG   A N   1 
ATOM   1800 C CA  . ARG   A 1 276 ? -9.28501  -10.75044 9.47982   1.000 22.66823 ?  256 ARG   A CA  1 
ATOM   1801 C C   . ARG   A 1 276 ? -9.39730  -9.27559  9.84926   1.000 23.25236 ?  256 ARG   A C   1 
ATOM   1802 O O   . ARG   A 1 276 ? -8.80906  -8.40171  9.20735   1.000 29.87449 ?  256 ARG   A O   1 
ATOM   1803 C CB  . ARG   A 1 276 ? -8.67065  -11.56807 10.62130  1.000 25.22036 ?  256 ARG   A CB  1 
ATOM   1804 C CG  . ARG   A 1 276 ? -7.16667  -11.76401 10.53299  1.000 25.34278 ?  256 ARG   A CG  1 
ATOM   1805 C CD  . ARG   A 1 276 ? -6.73384  -13.02763 11.26453  1.000 24.04676 ?  256 ARG   A CD  1 
ATOM   1806 N NE  . ARG   A 1 276 ? -5.33886  -12.95886 11.68065  1.000 21.15970 ?  256 ARG   A NE  1 
ATOM   1807 C CZ  . ARG   A 1 276 ? -4.93211  -12.43416 12.82804  1.000 22.89710 ?  256 ARG   A CZ  1 
ATOM   1808 N NH1 . ARG   A 1 276 ? -5.79166  -11.93829 13.70270  1.000 26.19640 ?  256 ARG   A NH1 1 
ATOM   1809 N NH2 . ARG   A 1 276 ? -3.63102  -12.40050 13.10219  1.000 23.20576 ?  256 ARG   A NH2 1 
ATOM   1810 N N   . PHE   A 1 277 ? -10.17048 -9.00443  10.89584  1.000 20.54444 ?  257 PHE   A N   1 
ATOM   1811 C CA  . PHE   A 1 277 ? -10.44895 -7.63833  11.30810  1.000 21.16581 ?  257 PHE   A CA  1 
ATOM   1812 C C   . PHE   A 1 277 ? -10.54975 -7.59853  12.82498  1.000 26.66919 ?  257 PHE   A C   1 
ATOM   1813 O O   . PHE   A 1 277 ? -11.16316 -8.47893  13.43395  1.000 24.91307 ?  257 PHE   A O   1 
ATOM   1814 C CB  . PHE   A 1 277 ? -11.74171 -7.12276  10.66523  1.000 19.75927 ?  257 PHE   A CB  1 
ATOM   1815 C CG  . PHE   A 1 277 ? -11.93920 -5.64146  10.79948  1.000 21.25022 ?  257 PHE   A CG  1 
ATOM   1816 C CD1 . PHE   A 1 277 ? -12.58782 -5.11007  11.90156  1.000 22.23817 ?  257 PHE   A CD1 1 
ATOM   1817 C CD2 . PHE   A 1 277 ? -11.47822 -4.77922  9.81856   1.000 18.49365 ?  257 PHE   A CD2 1 
ATOM   1818 C CE1 . PHE   A 1 277 ? -12.77092 -3.74683  12.02387  1.000 18.61343 ?  257 PHE   A CE1 1 
ATOM   1819 C CE2 . PHE   A 1 277 ? -11.65805 -3.41467  9.93534   1.000 20.59609 ?  257 PHE   A CE2 1 
ATOM   1820 C CZ  . PHE   A 1 277 ? -12.30597 -2.89822  11.03848  1.000 16.58859 ?  257 PHE   A CZ  1 
ATOM   1821 N N   . SER   A 1 278 ? -9.94579  -6.57583  13.42799  1.000 23.00720 ?  258 SER   A N   1 
ATOM   1822 C CA  . SER   A 1 278 ? -9.92287  -6.41460  14.87920  1.000 21.84556 ?  258 SER   A CA  1 
ATOM   1823 C C   . SER   A 1 278 ? -10.54688 -5.07288  15.23866  1.000 23.53454 ?  258 SER   A C   1 
ATOM   1824 O O   . SER   A 1 278 ? -9.91537  -4.02485  15.06780  1.000 22.02903 ?  258 SER   A O   1 
ATOM   1825 C CB  . SER   A 1 278 ? -8.49736  -6.51233  15.41986  1.000 18.38203 ?  258 SER   A CB  1 
ATOM   1826 O OG  . SER   A 1 278 ? -8.43893  -6.08873  16.77160  1.000 20.02556 ?  258 SER   A OG  1 
ATOM   1827 N N   . GLN   A 1 279 ? -11.78126 -5.10676  15.74575  1.000 18.86782 ?  259 GLN   A N   1 
ATOM   1828 C CA  . GLN   A 1 279 ? -12.42953 -3.87626  16.18740  1.000 20.48750 ?  259 GLN   A CA  1 
ATOM   1829 C C   . GLN   A 1 279 ? -11.79642 -3.34453  17.46597  1.000 22.81085 ?  259 GLN   A C   1 
ATOM   1830 O O   . GLN   A 1 279 ? -11.56362 -2.13671  17.59717  1.000 18.01940 ?  259 GLN   A O   1 
ATOM   1831 C CB  . GLN   A 1 279 ? -13.92049 -4.11427  16.41403  1.000 21.09114 ?  259 GLN   A CB  1 
ATOM   1832 C CG  . GLN   A 1 279 ? -14.67592 -4.65196  15.22128  1.000 19.05802 ?  259 GLN   A CG  1 
ATOM   1833 C CD  . GLN   A 1 279 ? -16.02792 -5.21191  15.61284  1.000 22.24915 ?  259 GLN   A CD  1 
ATOM   1834 O OE1 . GLN   A 1 279 ? -16.16770 -5.85694  16.65238  1.000 23.95102 ?  259 GLN   A OE1 1 
ATOM   1835 N NE2 . GLN   A 1 279 ? -17.03407 -4.96397  14.78368  1.000 22.16880 ?  259 GLN   A NE2 1 
ATOM   1836 N N   . ALA   A 1 280 ? -11.51316 -4.23295  18.41967  1.000 16.80123 ?  260 ALA   A N   1 
ATOM   1837 C CA  . ALA   A 1 280 ? -11.13372 -3.81434  19.76241  1.000 20.98869 ?  260 ALA   A CA  1 
ATOM   1838 C C   . ALA   A 1 280 ? -9.71967  -3.25448  19.84579  1.000 22.59912 ?  260 ALA   A C   1 
ATOM   1839 O O   . ALA   A 1 280 ? -9.43537  -2.47505  20.76148  1.000 23.82287 ?  260 ALA   A O   1 
ATOM   1840 C CB  . ALA   A 1 280 ? -11.28327 -4.98473  20.73533  1.000 17.28495 ?  260 ALA   A CB  1 
ATOM   1841 N N   . THR   A 1 281 ? -8.82699  -3.62565  18.92986  1.000 16.41069 ?  261 THR   A N   1 
ATOM   1842 C CA  . THR   A 1 281 ? -7.47494  -3.08421  18.92806  1.000 21.76577 ?  261 THR   A CA  1 
ATOM   1843 C C   . THR   A 1 281 ? -7.30331  -1.93256  17.94333  1.000 23.00532 ?  261 THR   A C   1 
ATOM   1844 O O   . THR   A 1 281 ? -6.17063  -1.50746  17.69713  1.000 21.45837 ?  261 THR   A O   1 
ATOM   1845 C CB  . THR   A 1 281 ? -6.45004  -4.18524  18.63650  1.000 21.11750 ?  261 THR   A CB  1 
ATOM   1846 O OG1 . THR   A 1 281 ? -6.73729  -4.79631  17.37410  1.000 23.20502 ?  261 THR   A OG1 1 
ATOM   1847 C CG2 . THR   A 1 281 ? -6.47796  -5.24509  19.73063  1.000 25.07334 ?  261 THR   A CG2 1 
ATOM   1848 N N   . GLY   A 1 282 ? -8.39444  -1.41800  17.37690  1.000 22.83973 ?  262 GLY   A N   1 
ATOM   1849 C CA  . GLY   A 1 282 ? -8.31828  -0.19366  16.60305  1.000 15.31183 ?  262 GLY   A CA  1 
ATOM   1850 C C   . GLY   A 1 282 ? -8.98118  -0.20858  15.23961  1.000 20.39059 ?  262 GLY   A C   1 
ATOM   1851 O O   . GLY   A 1 282 ? -8.65691  0.63213   14.39471  1.000 19.45052 ?  262 GLY   A O   1 
ATOM   1852 N N   . ASN   A 1 283 ? -9.91496  -1.13599  15.01139  1.000 18.25811 ?  263 ASN   A N   1 
ATOM   1853 C CA  . ASN   A 1 283 ? -10.59247 -1.28454  13.72083  1.000 19.74343 ?  263 ASN   A CA  1 
ATOM   1854 C C   . ASN   A 1 283 ? -9.56803  -1.46972  12.59616  1.000 18.86426 ?  263 ASN   A C   1 
ATOM   1855 O O   . ASN   A 1 283 ? -9.41373  -0.63786  11.69978  1.000 19.09871 ?  263 ASN   A O   1 
ATOM   1856 C CB  . ASN   A 1 283 ? -11.51064 -0.08825  13.43826  1.000 18.22824 ?  263 ASN   A CB  1 
ATOM   1857 C CG  . ASN   A 1 283 ? -12.91712 -0.29418  13.96103  1.000 20.33666 ?  263 ASN   A CG  1 
ATOM   1858 O OD1 . ASN   A 1 283 ? -13.80377 -0.73690  13.23051  1.000 18.90204 ?  263 ASN   A OD1 1 
ATOM   1859 N ND2 . ASN   A 1 283 ? -13.13092 0.03131   15.23005  1.000 18.17752 ?  263 ASN   A ND2 1 
ATOM   1860 N N   . LYS   A 1 284 ? -8.87098  -2.59931  12.67154  1.000 20.58701 ?  264 LYS   A N   1 
ATOM   1861 C CA  . LYS   A 1 284 ? -7.70355  -2.86089  11.84153  1.000 18.34861 ?  264 LYS   A CA  1 
ATOM   1862 C C   . LYS   A 1 284 ? -7.97865  -4.00235  10.87344  1.000 23.47916 ?  264 LYS   A C   1 
ATOM   1863 O O   . LYS   A 1 284 ? -8.52201  -5.03993  11.26642  1.000 21.30526 ?  264 LYS   A O   1 
ATOM   1864 C CB  . LYS   A 1 284 ? -6.49015  -3.19929  12.71008  1.000 16.32906 ?  264 LYS   A CB  1 
ATOM   1865 C CG  . LYS   A 1 284 ? -6.10743  -2.11067  13.69651  1.000 19.72053 ?  264 LYS   A CG  1 
ATOM   1866 C CD  . LYS   A 1 284 ? -4.69558  -2.31641  14.22273  1.000 21.97089 ?  264 LYS   A CD  1 
ATOM   1867 C CE  . LYS   A 1 284 ? -4.67161  -3.30860  15.37410  1.000 23.98339 ?  264 LYS   A CE  1 
ATOM   1868 N NZ  . LYS   A 1 284 ? -3.31873  -3.43665  15.98472  1.000 19.62662 ?  264 LYS   A NZ  1 
ATOM   1869 N N   . VAL   A 1 285 ? -7.59630  -3.80781  9.61506   1.000 21.99650 ?  265 VAL   A N   1 
ATOM   1870 C CA  . VAL   A 1 285 ? -7.58486  -4.88958  8.63650   1.000 25.04300 ?  265 VAL   A CA  1 
ATOM   1871 C C   . VAL   A 1 285 ? -6.27763  -5.65399  8.80016   1.000 20.14940 ?  265 VAL   A C   1 
ATOM   1872 O O   . VAL   A 1 285 ? -5.19168  -5.07381  8.69779   1.000 19.35552 ?  265 VAL   A O   1 
ATOM   1873 C CB  . VAL   A 1 285 ? -7.73961  -4.34962  7.20771   1.000 21.70653 ?  265 VAL   A CB  1 
ATOM   1874 C CG1 . VAL   A 1 285 ? -7.45770  -5.44659  6.18860   1.000 17.39502 ?  265 VAL   A CG1 1 
ATOM   1875 C CG2 . VAL   A 1 285 ? -9.13358  -3.77511  7.00827   1.000 22.05922 ?  265 VAL   A CG2 1 
ATOM   1876 N N   . ILE   A 1 286 ? -6.37851  -6.95373  9.06544   1.000 21.53616 ?  266 ILE   A N   1 
ATOM   1877 C CA  . ILE   A 1 286 ? -5.22622  -7.79244  9.37453   1.000 21.55776 ?  266 ILE   A CA  1 
ATOM   1878 C C   . ILE   A 1 286 ? -5.01343  -8.77469  8.23277   1.000 22.18092 ?  266 ILE   A C   1 
ATOM   1879 O O   . ILE   A 1 286 ? -5.96223  -9.42668  7.77958   1.000 27.32936 ?  266 ILE   A O   1 
ATOM   1880 C CB  . ILE   A 1 286 ? -5.41193  -8.53451  10.70923  1.000 23.88476 ?  266 ILE   A CB  1 
ATOM   1881 C CG1 . ILE   A 1 286 ? -5.70707  -7.54022  11.83305  1.000 23.48373 ?  266 ILE   A CG1 1 
ATOM   1882 C CG2 . ILE   A 1 286 ? -4.17567  -9.35789  11.03956  1.000 21.83249 ?  266 ILE   A CG2 1 
ATOM   1883 C CD1 . ILE   A 1 286 ? -6.27344  -8.18217  13.07769  1.000 25.34765 ?  266 ILE   A CD1 1 
ATOM   1884 N N   . VAL   A 1 287 ? -3.76900  -8.88179  7.77384   1.000 25.70525 ?  267 VAL   A N   1 
ATOM   1885 C CA  . VAL   A 1 287 ? -3.37846  -9.83105  6.73795   1.000 27.18737 ?  267 VAL   A CA  1 
ATOM   1886 C C   . VAL   A 1 287 ? -2.44389  -10.85477 7.36652   1.000 29.57710 ?  267 VAL   A C   1 
ATOM   1887 O O   . VAL   A 1 287 ? -1.34916  -10.50726 7.82778   1.000 26.62356 ?  267 VAL   A O   1 
ATOM   1888 C CB  . VAL   A 1 287 ? -2.70392  -9.13412  5.54650   1.000 29.05978 ?  267 VAL   A CB  1 
ATOM   1889 C CG1 . VAL   A 1 287 ? -2.26102  -10.16373 4.51671   1.000 26.27548 ?  267 VAL   A CG1 1 
ATOM   1890 C CG2 . VAL   A 1 287 ? -3.64197  -8.11580  4.92024   1.000 20.21108 ?  267 VAL   A CG2 1 
ATOM   1891 N N   . GLN   A 1 288 ? -2.87601  -12.11250 7.38795   1.000 23.34807 ?  268 GLN   A N   1 
ATOM   1892 C CA  . GLN   A 1 288 ? -2.04556  -13.21433 7.85455   1.000 26.16671 ?  268 GLN   A CA  1 
ATOM   1893 C C   . GLN   A 1 288 ? -1.21075  -13.73075 6.68912   1.000 27.30360 ?  268 GLN   A C   1 
ATOM   1894 O O   . GLN   A 1 288 ? -1.75770  -14.25509 5.71215   1.000 28.86707 ?  268 GLN   A O   1 
ATOM   1895 C CB  . GLN   A 1 288 ? -2.90696  -14.33361 8.43774   1.000 26.51874 ?  268 GLN   A CB  1 
ATOM   1896 C CG  . GLN   A 1 288 ? -2.14922  -15.30295 9.33257   1.000 27.07679 ?  268 GLN   A CG  1 
ATOM   1897 C CD  . GLN   A 1 288 ? -1.91034  -14.74999 10.72359  1.000 31.87871 ?  268 GLN   A CD  1 
ATOM   1898 O OE1 . GLN   A 1 288 ? -2.66646  -13.90721 11.20675  1.000 29.18394 ?  268 GLN   A OE1 1 
ATOM   1899 N NE2 . GLN   A 1 288 ? -0.85253  -15.22115 11.37514  1.000 28.67395 ?  268 GLN   A NE2 1 
ATOM   1900 N N   . TYR   A 1 289 ? 0.11041   -13.57761 6.78924   1.000 26.57855 ?  269 TYR   A N   1 
ATOM   1901 C CA  . TYR   A 1 289 ? 1.01933   -14.04709 5.75413   1.000 27.54282 ?  269 TYR   A CA  1 
ATOM   1902 C C   . TYR   A 1 289 ? 1.88732   -15.21761 6.19401   1.000 26.96290 ?  269 TYR   A C   1 
ATOM   1903 O O   . TYR   A 1 289 ? 2.52261   -15.84719 5.34080   1.000 28.25469 ?  269 TYR   A O   1 
ATOM   1904 C CB  . TYR   A 1 289 ? 1.91828   -12.89583 5.26600   1.000 26.21247 ?  269 TYR   A CB  1 
ATOM   1905 C CG  . TYR   A 1 289 ? 3.01111   -12.47521 6.23136   1.000 27.59546 ?  269 TYR   A CG  1 
ATOM   1906 C CD1 . TYR   A 1 289 ? 4.25075   -13.10645 6.23308   1.000 31.90827 ?  269 TYR   A CD1 1 
ATOM   1907 C CD2 . TYR   A 1 289 ? 2.80695   -11.43659 7.13095   1.000 25.46052 ?  269 TYR   A CD2 1 
ATOM   1908 C CE1 . TYR   A 1 289 ? 5.24947   -12.72275 7.10926   1.000 29.30398 ?  269 TYR   A CE1 1 
ATOM   1909 C CE2 . TYR   A 1 289 ? 3.80175   -11.04489 8.00966   1.000 26.82053 ?  269 TYR   A CE2 1 
ATOM   1910 C CZ  . TYR   A 1 289 ? 5.01957   -11.69204 7.99495   1.000 24.93147 ?  269 TYR   A CZ  1 
ATOM   1911 O OH  . TYR   A 1 289 ? 6.01216   -11.30800 8.86722   1.000 25.60497 ?  269 TYR   A OH  1 
ATOM   1912 N N   . GLY   A 1 290 ? 1.93658   -15.52466 7.48793   1.000 27.71940 ?  270 GLY   A N   1 
ATOM   1913 C CA  . GLY   A 1 290 ? 2.76252   -16.59957 7.98095   1.000 26.17514 ?  270 GLY   A CA  1 
ATOM   1914 C C   . GLY   A 1 290 ? 2.19811   -17.24800 9.22822   1.000 32.65357 ?  270 GLY   A C   1 
ATOM   1915 O O   . GLY   A 1 290 ? 1.14367   -16.85857 9.74082   1.000 30.61822 ?  270 GLY   A O   1 
ATOM   1916 N N   . PRO   A 1 291 ? 2.89738   -18.25804 9.73940   1.000 35.80831 ?  271 PRO   A N   1 
ATOM   1917 C CA  . PRO   A 1 291 ? 2.37343   -19.01865 10.87894  1.000 38.27183 ?  271 PRO   A CA  1 
ATOM   1918 C C   . PRO   A 1 291 ? 2.46628   -18.24139 12.18350  1.000 33.30858 ?  271 PRO   A C   1 
ATOM   1919 O O   . PRO   A 1 291 ? 3.22274   -17.27764 12.32628  1.000 32.71515 ?  271 PRO   A O   1 
ATOM   1920 C CB  . PRO   A 1 291 ? 3.26227   -20.26783 10.92966  1.000 38.59116 ?  271 PRO   A CB  1 
ATOM   1921 C CG  . PRO   A 1 291 ? 4.44715   -19.96399 10.09378  1.000 35.86378 ?  271 PRO   A CG  1 
ATOM   1922 C CD  . PRO   A 1 291 ? 4.09616   -18.87031 9.14198   1.000 39.45733 ?  271 PRO   A CD  1 
ATOM   1923 N N   . THR   A 1 292 ? 1.67113   -18.69611 13.14900  1.000 30.57527 ?  272 THR   A N   1 
ATOM   1924 C CA  . THR   A 1 292 ? 1.71675   -18.20906 14.52023  1.000 28.91145 ?  272 THR   A CA  1 
ATOM   1925 C C   . THR   A 1 292 ? 1.10856   -19.28354 15.40774  1.000 33.44007 ?  272 THR   A C   1 
ATOM   1926 O O   . THR   A 1 292 ? 0.37051   -20.15168 14.93657  1.000 31.25259 ?  272 THR   A O   1 
ATOM   1927 C CB  . THR   A 1 292 ? 0.97276   -16.87801 14.68242  1.000 34.29585 ?  272 THR   A CB  1 
ATOM   1928 O OG1 . THR   A 1 292 ? 1.02708   -16.45814 16.05202  1.000 33.30408 ?  272 THR   A OG1 1 
ATOM   1929 C CG2 . THR   A 1 292 ? -0.47963  -17.02029 14.25386  1.000 30.03096 ?  272 THR   A CG2 1 
ATOM   1930 N N   . THR   A 1 293 ? 1.43580   -19.22683 16.69635  1.000 34.44087 ?  273 THR   A N   1 
ATOM   1931 C CA  . THR   A 1 293 ? 0.92990   -20.20154 17.65325  1.000 33.24685 ?  273 THR   A CA  1 
ATOM   1932 C C   . THR   A 1 293 ? -0.15569  -19.63853 18.56045  1.000 35.03967 ?  273 THR   A C   1 
ATOM   1933 O O   . THR   A 1 293 ? -0.66409  -20.36780 19.41779  1.000 31.37022 ?  273 THR   A O   1 
ATOM   1934 C CB  . THR   A 1 293 ? 2.07440   -20.76067 18.50803  1.000 36.35384 ?  273 THR   A CB  1 
ATOM   1935 O OG1 . THR   A 1 293 ? 2.53267   -19.75535 19.42041  1.000 43.41497 ?  273 THR   A OG1 1 
ATOM   1936 C CG2 . THR   A 1 293 ? 3.23286   -21.21013 17.62514  1.000 33.00492 ?  273 THR   A CG2 1 
ATOM   1937 N N   . GLU   A 1 294 ? -0.52346  -18.36942 18.39582  1.000 33.53466 ?  274 GLU   A N   1 
ATOM   1938 C CA  . GLU   A 1 294 ? -1.58770  -17.79571 19.20723  1.000 33.04324 ?  274 GLU   A CA  1 
ATOM   1939 C C   . GLU   A 1 294 ? -2.90933  -18.49633 18.91723  1.000 28.35964 ?  274 GLU   A C   1 
ATOM   1940 O O   . GLU   A 1 294 ? -3.26143  -18.74805 17.76159  1.000 31.84608 ?  274 GLU   A O   1 
ATOM   1941 C CB  . GLU   A 1 294 ? -1.70038  -16.29033 18.95162  1.000 35.56349 ?  274 GLU   A CB  1 
ATOM   1942 C CG  . GLU   A 1 294 ? -1.82741  -15.90756 17.48965  1.000 41.29709 ?  274 GLU   A CG  1 
ATOM   1943 C CD  . GLU   A 1 294 ? -1.32987  -14.50302 17.19390  1.000 40.71495 ?  274 GLU   A CD  1 
ATOM   1944 O OE1 . GLU   A 1 294 ? -2.00539  -13.53266 17.59966  1.000 29.21680 ?  274 GLU   A OE1 1 
ATOM   1945 O OE2 . GLU   A 1 294 ? -0.26775  -14.36833 16.55175  1.000 36.18729 ?  274 GLU   A OE2 1 
ATOM   1946 N N   . THR   A 1 295 ? -3.63600  -18.82536 19.98353  1.000 27.69666 ?  275 THR   A N   1 
ATOM   1947 C CA  . THR   A 1 295 ? -4.82604  -19.65806 19.89180  1.000 33.63961 ?  275 THR   A CA  1 
ATOM   1948 C C   . THR   A 1 295 ? -6.12636  -18.87529 19.99718  1.000 32.75092 ?  275 THR   A C   1 
ATOM   1949 O O   . THR   A 1 295 ? -7.20008  -19.48084 19.91969  1.000 29.14550 ?  275 THR   A O   1 
ATOM   1950 C CB  . THR   A 1 295 ? -4.79108  -20.74408 20.97115  1.000 31.24250 ?  275 THR   A CB  1 
ATOM   1951 O OG1 . THR   A 1 295 ? -4.64013  -20.13399 22.26000  1.000 28.69774 ?  275 THR   A OG1 1 
ATOM   1952 C CG2 . THR   A 1 295 ? -3.62800  -21.69159 20.72699  1.000 35.49256 ?  275 THR   A CG2 1 
ATOM   1953 N N   . LEU   A 1 296 ? -6.06544  -17.55663 20.17182  1.000 27.79920 ?  276 LEU   A N   1 
ATOM   1954 C CA  . LEU   A 1 296 ? -7.27280  -16.74542 20.15969  1.000 29.67352 ?  276 LEU   A CA  1 
ATOM   1955 C C   . LEU   A 1 296 ? -7.96797  -16.85758 18.80258  1.000 26.87649 ?  276 LEU   A C   1 
ATOM   1956 O O   . LEU   A 1 296 ? -7.43694  -17.41685 17.84303  1.000 28.48284 ?  276 LEU   A O   1 
ATOM   1957 C CB  . LEU   A 1 296 ? -6.95151  -15.28064 20.46817  1.000 27.50492 ?  276 LEU   A CB  1 
ATOM   1958 C CG  . LEU   A 1 296 ? -6.54429  -14.85043 21.88338  1.000 28.35029 ?  276 LEU   A CG  1 
ATOM   1959 C CD1 . LEU   A 1 296 ? -5.20124  -15.43013 22.32931  1.000 36.25092 ?  276 LEU   A CD1 1 
ATOM   1960 C CD2 . LEU   A 1 296 ? -6.52772  -13.32996 21.97915  1.000 23.30136 ?  276 LEU   A CD2 1 
ATOM   1961 N N   . SER   A 1 297 ? -9.17925  -16.31968 18.72968  1.000 22.72426 ?  277 SER   A N   1 
ATOM   1962 C CA  . SER   A 1 297 ? -9.96885  -16.36684 17.50962  1.000 26.79514 ?  277 SER   A CA  1 
ATOM   1963 C C   . SER   A 1 297 ? -10.22681 -14.95544 17.00542  1.000 25.52621 ?  277 SER   A C   1 
ATOM   1964 O O   . SER   A 1 297 ? -10.50960 -14.04587 17.79089  1.000 26.14671 ?  277 SER   A O   1 
ATOM   1965 C CB  . SER   A 1 297 ? -11.29370 -17.09737 17.73593  1.000 25.71693 ?  277 SER   A CB  1 
ATOM   1966 O OG  . SER   A 1 297 ? -12.21482 -16.27221 18.42421  1.000 31.51501 ?  277 SER   A OG  1 
ATOM   1967 N N   . SER   A 1 298 ? -10.12209 -14.78185 15.69001  1.000 28.16171 ?  278 SER   A N   1 
ATOM   1968 C CA  . SER   A 1 298 ? -10.30474 -13.49478 15.05362  1.000 27.75945 ?  278 SER   A CA  1 
ATOM   1969 C C   . SER   A 1 298 ? -11.43672 -13.56722 14.03669  1.000 26.33353 ?  278 SER   A C   1 
ATOM   1970 O O   . SER   A 1 298 ? -11.61391 -14.59893 13.37878  1.000 27.92490 ?  278 SER   A O   1 
ATOM   1971 C CB  . SER   A 1 298 ? -9.01295  -13.04009 14.35643  1.000 24.07451 ?  278 SER   A CB  1 
ATOM   1972 O OG  . SER   A 1 298 ? -9.12727  -11.72720 13.84157  1.000 27.82854 ?  278 SER   A OG  1 
ATOM   1973 N N   . PRO   A 1 299 ? -12.22148 -12.50084 13.89719  1.000 25.45614 ?  279 PRO   A N   1 
ATOM   1974 C CA  . PRO   A 1 299 ? -13.32792 -12.50979 12.93184  1.000 25.51125 ?  279 PRO   A CA  1 
ATOM   1975 C C   . PRO   A 1 299 ? -12.82492 -12.70613 11.50946  1.000 24.21535 ?  279 PRO   A C   1 
ATOM   1976 O O   . PRO   A 1 299 ? -11.87690 -12.05111 11.06949  1.000 24.28073 ?  279 PRO   A O   1 
ATOM   1977 C CB  . PRO   A 1 299 ? -13.96854 -11.12953 13.12236  1.000 23.16111 ?  279 PRO   A CB  1 
ATOM   1978 C CG  . PRO   A 1 299 ? -13.57693 -10.72811 14.51261  1.000 26.75238 ?  279 PRO   A CG  1 
ATOM   1979 C CD  . PRO   A 1 299 ? -12.19103 -11.25981 14.68400  1.000 26.44950 ?  279 PRO   A CD  1 
ATOM   1980 N N   . VAL   A 1 300 ? -13.47283 -13.61826 10.79034  1.000 25.94953 ?  280 VAL   A N   1 
ATOM   1981 C CA  . VAL   A 1 300 ? -13.08828 -13.92975 9.41809   1.000 29.01650 ?  280 VAL   A CA  1 
ATOM   1982 C C   . VAL   A 1 300 ? -13.66455 -12.85051 8.50799   1.000 27.98771 ?  280 VAL   A C   1 
ATOM   1983 O O   . VAL   A 1 300 ? -14.88244 -12.73878 8.35357   1.000 26.04166 ?  280 VAL   A O   1 
ATOM   1984 C CB  . VAL   A 1 300 ? -13.56666 -15.32396 8.99969   1.000 24.30314 ?  280 VAL   A CB  1 
ATOM   1985 C CG1 . VAL   A 1 300 ? -13.21541 -15.58597 7.54200   1.000 25.83204 ?  280 VAL   A CG1 1 
ATOM   1986 C CG2 . VAL   A 1 300 ? -12.95429 -16.37525 9.90028   1.000 25.67400 ?  280 VAL   A CG2 1 
ATOM   1987 N N   . LEU   A 1 301 ? -12.78860 -12.05171 7.90165   1.000 22.10879 ?  281 LEU   A N   1 
ATOM   1988 C CA  . LEU   A 1 301 ? -13.22309 -11.03089 6.95617   1.000 24.42297 ?  281 LEU   A CA  1 
ATOM   1989 C C   . LEU   A 1 301 ? -13.16940 -11.54053 5.52042   1.000 30.85243 ?  281 LEU   A C   1 
ATOM   1990 O O   . LEU   A 1 301 ? -14.12393 -11.36316 4.75658   1.000 23.88006 ?  281 LEU   A O   1 
ATOM   1991 C CB  . LEU   A 1 301 ? -12.36288 -9.77494  7.10748   1.000 20.43834 ?  281 LEU   A CB  1 
ATOM   1992 C CG  . LEU   A 1 301 ? -12.53692 -8.68308  6.05176   1.000 27.23906 ?  281 LEU   A CG  1 
ATOM   1993 C CD1 . LEU   A 1 301 ? -13.93923 -8.08548  6.10144   1.000 25.25397 ?  281 LEU   A CD1 1 
ATOM   1994 C CD2 . LEU   A 1 301 ? -11.47887 -7.60503  6.22781   1.000 22.21639 ?  281 LEU   A CD2 1 
ATOM   1995 N N   . GLY   A 1 302 ? -12.06572 -12.17856 5.14268   1.000 25.55527 ?  282 GLY   A N   1 
ATOM   1996 C CA  . GLY   A 1 302 ? -11.92140 -12.66519 3.78885   1.000 28.65752 ?  282 GLY   A CA  1 
ATOM   1997 C C   . GLY   A 1 302 ? -10.66795 -13.48312 3.57437   1.000 30.71623 ?  282 GLY   A C   1 
ATOM   1998 O O   . GLY   A 1 302 ? -10.15362 -14.10474 4.50984   1.000 31.94200 ?  282 GLY   A O   1 
ATOM   1999 N N   . LYS   A 1 303 ? -10.16305 -13.48176 2.34239   1.000 28.62406 ?  283 LYS   A N   1 
ATOM   2000 C CA  . LYS   A 1 303 ? -9.00685  -14.29401 1.99018   1.000 31.98357 ?  283 LYS   A CA  1 
ATOM   2001 C C   . LYS   A 1 303 ? -8.42167  -13.79302 0.68054   1.000 29.10432 ?  283 LYS   A C   1 
ATOM   2002 O O   . LYS   A 1 303 ? -9.16461  -13.53146 -0.27058  1.000 30.26910 ?  283 LYS   A O   1 
ATOM   2003 C CB  . LYS   A 1 303 ? -9.39310  -15.76851 1.85375   1.000 35.65712 ?  283 LYS   A CB  1 
ATOM   2004 C CG  . LYS   A 1 303 ? -8.22657  -16.68787 1.55688   1.000 35.55775 ?  283 LYS   A CG  1 
ATOM   2005 C CD  . LYS   A 1 303 ? -8.66710  -18.13996 1.55544   1.000 39.22689 ?  283 LYS   A CD  1 
ATOM   2006 C CE  . LYS   A 1 303 ? -8.78705  -18.68524 2.96721   1.000 42.08936 ?  283 LYS   A CE  1 
ATOM   2007 N NZ  . LYS   A 1 303 ? -10.15450 -19.21127 3.23863   1.000 38.69195 ?  283 LYS   A NZ  1 
ATOM   2008 N N   . VAL   A 1 304 ? -7.09466  -13.66066 0.63878   1.000 26.84083 ?  284 VAL   A N   1 
ATOM   2009 C CA  . VAL   A 1 304 ? -6.39603  -13.44350 -0.62138  1.000 30.38068 ?  284 VAL   A CA  1 
ATOM   2010 C C   . VAL   A 1 304 ? -6.51647  -14.69642 -1.47855  1.000 31.36271 ?  284 VAL   A C   1 
ATOM   2011 O O   . VAL   A 1 304 ? -6.42367  -15.82413 -0.97455  1.000 31.63746 ?  284 VAL   A O   1 
ATOM   2012 C CB  . VAL   A 1 304 ? -4.92202  -13.08556 -0.36077  1.000 26.44835 ?  284 VAL   A CB  1 
ATOM   2013 C CG1 . VAL   A 1 304 ? -4.16231  -12.92753 -1.67230  1.000 25.11843 ?  284 VAL   A CG1 1 
ATOM   2014 C CG2 . VAL   A 1 304 ? -4.81688  -11.82166 0.48006   1.000 28.32325 ?  284 VAL   A CG2 1 
ATOM   2015 N N   . VAL   A 1 305 ? -6.72584  -14.50664 -2.78599  1.000 32.79344 ?  285 VAL   A N   1 
ATOM   2016 C CA  . VAL   A 1 305 ? -6.92446  -15.65110 -3.67045  1.000 32.22503 ?  285 VAL   A CA  1 
ATOM   2017 C C   . VAL   A 1 305 ? -5.69586  -16.56160 -3.64813  1.000 33.05403 ?  285 VAL   A C   1 
ATOM   2018 O O   . VAL   A 1 305 ? -4.57578  -16.14421 -3.32803  1.000 35.49006 ?  285 VAL   A O   1 
ATOM   2019 C CB  . VAL   A 1 305 ? -7.24864  -15.20031 -5.10349  1.000 32.28405 ?  285 VAL   A CB  1 
ATOM   2020 C CG1 . VAL   A 1 305 ? -8.48335  -14.31651 -5.10978  1.000 31.17275 ?  285 VAL   A CG1 1 
ATOM   2021 C CG2 . VAL   A 1 305 ? -6.06712  -14.46964 -5.71901  1.000 34.77671 ?  285 VAL   A CG2 1 
ATOM   2022 N N   . ASP   A 1 306 ? -5.92387  -17.83275 -3.98852  1.000 36.58952 ?  286 ASP   A N   1 
ATOM   2023 C CA  . ASP   A 1 306 ? -4.87667  -18.84352 -3.86725  1.000 35.19376 ?  286 ASP   A CA  1 
ATOM   2024 C C   . ASP   A 1 306 ? -3.67945  -18.51722 -4.75304  1.000 29.93296 ?  286 ASP   A C   1 
ATOM   2025 O O   . ASP   A 1 306 ? -2.52611  -18.60969 -4.31684  1.000 32.11365 ?  286 ASP   A O   1 
ATOM   2026 C CB  . ASP   A 1 306 ? -5.44103  -20.22246 -4.21383  1.000 37.69449 ?  286 ASP   A CB  1 
ATOM   2027 C CG  . ASP   A 1 306 ? -6.37168  -20.75904 -3.14185  1.000 35.46129 ?  286 ASP   A CG  1 
ATOM   2028 O OD1 . ASP   A 1 306 ? -6.26249  -20.31071 -1.98125  1.000 43.24819 ?  286 ASP   A OD1 1 
ATOM   2029 O OD2 . ASP   A 1 306 ? -7.20864  -21.63185 -3.45732  1.000 43.02918 ?  286 ASP   A OD2 1 
ATOM   2030 N N   . SER   A 1 307 ? -3.93451  -18.12717 -6.00361  1.000 34.36417 ?  287 SER   A N   1 
ATOM   2031 C CA  . SER   A 1 307 ? -2.85791  -17.89770 -6.96106  1.000 33.66272 ?  287 SER   A CA  1 
ATOM   2032 C C   . SER   A 1 307 ? -2.02706  -16.65963 -6.64649  1.000 36.35557 ?  287 SER   A C   1 
ATOM   2033 O O   . SER   A 1 307 ? -0.99397  -16.45054 -7.29095  1.000 37.92607 ?  287 SER   A O   1 
ATOM   2034 C CB  . SER   A 1 307 ? -3.43236  -17.78772 -8.37466  1.000 38.76937 ?  287 SER   A CB  1 
ATOM   2035 O OG  . SER   A 1 307 ? -3.69695  -16.43892 -8.71782  1.000 44.05981 ?  287 SER   A OG  1 
ATOM   2036 N N   . HIS   A 1 308 ? -2.44315  -15.84077 -5.68229  1.000 40.96245 ?  288 HIS   A N   1 
ATOM   2037 C CA  . HIS   A 1 308 ? -1.70712  -14.64306 -5.30273  1.000 34.58722 ?  288 HIS   A CA  1 
ATOM   2038 C C   . HIS   A 1 308 ? -1.11749  -14.72645 -3.90178  1.000 36.94129 ?  288 HIS   A C   1 
ATOM   2039 O O   . HIS   A 1 308 ? -0.40985  -13.80240 -3.48995  1.000 39.21187 ?  288 HIS   A O   1 
ATOM   2040 C CB  . HIS   A 1 308 ? -2.61489  -13.41131 -5.39992  1.000 30.74635 ?  288 HIS   A CB  1 
ATOM   2041 C CG  . HIS   A 1 308 ? -2.97836  -13.03481 -6.80267  1.000 38.87811 ?  288 HIS   A CG  1 
ATOM   2042 N ND1 . HIS   A 1 308 ? -3.96135  -12.11372 -7.09449  1.000 37.23273 ?  288 HIS   A ND1 1 
ATOM   2043 C CD2 . HIS   A 1 308 ? -2.49475  -13.45849 -7.99401  1.000 37.51945 ?  288 HIS   A CD2 1 
ATOM   2044 C CE1 . HIS   A 1 308 ? -4.06635  -11.98512 -8.40490  1.000 31.36370 ?  288 HIS   A CE1 1 
ATOM   2045 N NE2 . HIS   A 1 308 ? -3.18717  -12.78991 -8.97389  1.000 37.74069 ?  288 HIS   A NE2 1 
ATOM   2046 N N   . ALA   A 1 309 ? -1.38158  -15.80832 -3.16316  1.000 38.84874 ?  289 ALA   A N   1 
ATOM   2047 C CA  . ALA   A 1 309 ? -0.99585  -15.86335 -1.75616  1.000 32.66816 ?  289 ALA   A CA  1 
ATOM   2048 C C   . ALA   A 1 309 ? 0.51571   -15.93806 -1.57376  1.000 35.89676 ?  289 ALA   A C   1 
ATOM   2049 O O   . ALA   A 1 309 ? 1.03560   -15.46441 -0.55704  1.000 34.71903 ?  289 ALA   A O   1 
ATOM   2050 C CB  . ALA   A 1 309 ? -1.67242  -17.05156 -1.07088  1.000 31.50093 ?  289 ALA   A CB  1 
ATOM   2051 N N   . ASP   A 1 310 ? 1.23828   -16.52053 -2.53313  1.000 34.99808 ?  290 ASP   A N   1 
ATOM   2052 C CA  . ASP   A 1 310 ? 2.69011   -16.59267 -2.41724  1.000 42.92898 ?  290 ASP   A CA  1 
ATOM   2053 C C   . ASP   A 1 310 ? 3.36584   -15.23269 -2.55049  1.000 36.17401 ?  290 ASP   A C   1 
ATOM   2054 O O   . ASP   A 1 310 ? 4.56656   -15.12816 -2.27914  1.000 35.73633 ?  290 ASP   A O   1 
ATOM   2055 C CB  . ASP   A 1 310 ? 3.25256   -17.57482 -3.45156  1.000 40.46463 ?  290 ASP   A CB  1 
ATOM   2056 C CG  . ASP   A 1 310 ? 2.91578   -17.19188 -4.88610  1.000 46.01190 ?  290 ASP   A CG  1 
ATOM   2057 O OD1 . ASP   A 1 310 ? 2.56508   -16.02153 -5.14974  1.000 43.95539 ?  290 ASP   A OD1 1 
ATOM   2058 O OD2 . ASP   A 1 310 ? 3.01406   -18.07630 -5.76172  1.000 46.51927 ?  290 ASP   A OD2 1 
ATOM   2059 N N   . ARG   A 1 311 ? 2.62965   -14.19722 -2.95474  1.000 35.36175 ?  291 ARG   A N   1 
ATOM   2060 C CA  . ARG   A 1 311 ? 3.17600   -12.85166 -3.06541  1.000 32.25555 ?  291 ARG   A CA  1 
ATOM   2061 C C   . ARG   A 1 311 ? 3.26535   -12.13040 -1.72661  1.000 31.54964 ?  291 ARG   A C   1 
ATOM   2062 O O   . ARG   A 1 311 ? 3.85458   -11.04578 -1.66468  1.000 30.99560 ?  291 ARG   A O   1 
ATOM   2063 C CB  . ARG   A 1 311 ? 2.32245   -12.01796 -4.02516  1.000 32.82521 ?  291 ARG   A CB  1 
ATOM   2064 C CG  . ARG   A 1 311 ? 2.28654   -12.53173 -5.45365  1.000 38.70344 ?  291 ARG   A CG  1 
ATOM   2065 C CD  . ARG   A 1 311 ? 1.50608   -11.57727 -6.34424  1.000 35.32573 ?  291 ARG   A CD  1 
ATOM   2066 N NE  . ARG   A 1 311 ? 1.18228   -12.16397 -7.63894  1.000 40.32328 ?  291 ARG   A NE  1 
ATOM   2067 C CZ  . ARG   A 1 311 ? 0.25460   -11.69422 -8.46202  1.000 39.85371 ?  291 ARG   A CZ  1 
ATOM   2068 N NH1 . ARG   A 1 311 ? -0.46770  -10.62911 -8.15426  1.000 32.31760 ?  291 ARG   A NH1 1 
ATOM   2069 N NH2 . ARG   A 1 311 ? 0.04721   -12.30750 -9.62374  1.000 39.12732 ?  291 ARG   A NH2 1 
ATOM   2070 N N   . LEU   A 1 312 ? 2.70467   -12.70125 -0.65996  1.000 30.06407 ?  292 LEU   A N   1 
ATOM   2071 C CA  . LEU   A 1 312 ? 2.58273   -11.98676 0.60427   1.000 33.28351 ?  292 LEU   A CA  1 
ATOM   2072 C C   . LEU   A 1 312 ? 3.83882   -12.06221 1.46086   1.000 29.57690 ?  292 LEU   A C   1 
ATOM   2073 O O   . LEU   A 1 312 ? 4.02085   -11.21039 2.33827   1.000 27.54156 ?  292 LEU   A O   1 
ATOM   2074 C CB  . LEU   A 1 312 ? 1.39142   -12.53067 1.39462   1.000 27.49056 ?  292 LEU   A CB  1 
ATOM   2075 C CG  . LEU   A 1 312 ? 0.02886   -12.34816 0.72280   1.000 30.46251 ?  292 LEU   A CG  1 
ATOM   2076 C CD1 . LEU   A 1 312 ? -1.06890  -12.96141 1.56645   1.000 22.53473 ?  292 LEU   A CD1 1 
ATOM   2077 C CD2 . LEU   A 1 312 ? -0.25338  -10.87681 0.46001   1.000 27.62733 ?  292 LEU   A CD2 1 
ATOM   2078 N N   . ALA   A 1 313 ? 4.70287   -13.05453 1.23086   1.000 29.16251 ?  293 ALA   A N   1 
ATOM   2079 C CA  . ALA   A 1 313 ? 5.89369   -13.20574 2.06186   1.000 31.05410 ?  293 ALA   A CA  1 
ATOM   2080 C C   . ALA   A 1 313 ? 6.82370   -12.00715 1.92535   1.000 25.01745 ?  293 ALA   A C   1 
ATOM   2081 O O   . ALA   A 1 313 ? 7.39055   -11.53620 2.91862   1.000 28.80746 ?  293 ALA   A O   1 
ATOM   2082 C CB  . ALA   A 1 313 ? 6.62742   -14.49694 1.70082   1.000 25.29765 ?  293 ALA   A CB  1 
ATOM   2083 N N   . GLU   A 1 314 ? 6.99288   -11.49700 0.70294   1.000 23.35497 ?  294 GLU   A N   1 
ATOM   2084 C CA  . GLU   A 1 314 ? 7.87169   -10.34946 0.50564   1.000 31.28101 ?  294 GLU   A CA  1 
ATOM   2085 C C   . GLU   A 1 314 ? 7.25375   -9.06751  1.04915   1.000 30.52462 ?  294 GLU   A C   1 
ATOM   2086 O O   . GLU   A 1 314 ? 7.98130   -8.12561  1.38372   1.000 30.93892 ?  294 GLU   A O   1 
ATOM   2087 C CB  . GLU   A 1 314 ? 8.21922   -10.19531 -0.97660  1.000 31.39607 ?  294 GLU   A CB  1 
ATOM   2088 C CG  . GLU   A 1 314 ? 7.25922   -9.33223  -1.77811  1.000 34.15162 ?  294 GLU   A CG  1 
ATOM   2089 C CD  . GLU   A 1 314 ? 7.60791   -9.29848  -3.25414  1.000 50.91415 ?  294 GLU   A CD  1 
ATOM   2090 O OE1 . GLU   A 1 314 ? 7.28467   -10.27434 -3.96518  1.000 53.01284 ?  294 GLU   A OE1 1 
ATOM   2091 O OE2 . GLU   A 1 314 ? 8.20479   -8.29809  -3.70358  1.000 53.49912 ?  294 GLU   A OE2 1 
ATOM   2092 N N   . VAL   A 1 315 ? 5.92469   -9.00970  1.14787   1.000 23.86642 ?  295 VAL   A N   1 
ATOM   2093 C CA  . VAL   A 1 315 ? 5.28270   -7.85873  1.77302   1.000 22.23200 ?  295 VAL   A CA  1 
ATOM   2094 C C   . VAL   A 1 315 ? 5.49747   -7.89323  3.28037   1.000 28.14808 ?  295 VAL   A C   1 
ATOM   2095 O O   . VAL   A 1 315 ? 5.86872   -6.88649  3.89445   1.000 21.73791 ?  295 VAL   A O   1 
ATOM   2096 C CB  . VAL   A 1 315 ? 3.78638   -7.81463  1.41508   1.000 27.98861 ?  295 VAL   A CB  1 
ATOM   2097 C CG1 . VAL   A 1 315 ? 3.11216   -6.63394  2.09761   1.000 25.70987 ?  295 VAL   A CG1 1 
ATOM   2098 C CG2 . VAL   A 1 315 ? 3.60534   -7.73503  -0.08882  1.000 23.76518 ?  295 VAL   A CG2 1 
ATOM   2099 N N   . GLY   A 1 316 ? 5.28514   -9.05977  3.89439   1.000 24.99305 ?  296 GLY   A N   1 
ATOM   2100 C CA  . GLY   A 1 316 ? 5.45785   -9.17231  5.33387   1.000 28.13570 ?  296 GLY   A CA  1 
ATOM   2101 C C   . GLY   A 1 316 ? 6.87616   -8.87954  5.78445   1.000 27.25227 ?  296 GLY   A C   1 
ATOM   2102 O O   . GLY   A 1 316 ? 7.09104   -8.32282  6.86346   1.000 26.29208 ?  296 GLY   A O   1 
ATOM   2103 N N   . LYS   A 1 317 ? 7.86346   -9.24861  4.96562   1.000 27.82533 ?  297 LYS   A N   1 
ATOM   2104 C CA  . LYS   A 1 317 ? 9.25266   -8.95879  5.30698   1.000 31.16679 ?  297 LYS   A CA  1 
ATOM   2105 C C   . LYS   A 1 317 ? 9.52996   -7.46119  5.25068   1.000 27.07477 ?  297 LYS   A C   1 
ATOM   2106 O O   . LYS   A 1 317 ? 10.16279  -6.90185  6.15412   1.000 30.10951 ?  297 LYS   A O   1 
ATOM   2107 C CB  . LYS   A 1 317 ? 10.19359  -9.71932  4.37158   1.000 33.17860 ?  297 LYS   A CB  1 
ATOM   2108 C CG  . LYS   A 1 317 ? 10.46529  -11.15399 4.79575   1.000 38.21153 ?  297 LYS   A CG  1 
ATOM   2109 C CD  . LYS   A 1 317 ? 11.94824  -11.37947 5.04825   1.000 41.68887 ?  297 LYS   A CD  1 
ATOM   2110 C CE  . LYS   A 1 317 ? 12.17682  -12.48464 6.06791   1.000 43.04764 ?  297 LYS   A CE  1 
ATOM   2111 N NZ  . LYS   A 1 317 ? 13.55378  -12.43773 6.63562   1.000 49.73828 ?  297 LYS   A NZ  1 
ATOM   2112 N N   . ALA   A 1 318 ? 9.06043   -6.79379  4.19370   1.000 26.00300 ?  298 ALA   A N   1 
ATOM   2113 C CA  . ALA   A 1 318 ? 9.27083   -5.35443  4.07425   1.000 27.86146 ?  298 ALA   A CA  1 
ATOM   2114 C C   . ALA   A 1 318 ? 8.46950   -4.58865  5.11907   1.000 28.64319 ?  298 ALA   A C   1 
ATOM   2115 O O   . ALA   A 1 318 ? 8.96511   -3.61425  5.69744   1.000 29.46432 ?  298 ALA   A O   1 
ATOM   2116 C CB  . ALA   A 1 318 ? 8.90482   -4.88440  2.66748   1.000 27.67523 ?  298 ALA   A CB  1 
ATOM   2117 N N   . VAL   A 1 319 ? 7.22670   -5.00868  5.36759   1.000 28.15103 ?  299 VAL   A N   1 
ATOM   2118 C CA  . VAL   A 1 319 ? 6.42199   -4.37810  6.41049   1.000 22.65972 ?  299 VAL   A CA  1 
ATOM   2119 C C   . VAL   A 1 319 ? 7.06452   -4.59015  7.77582   1.000 23.19687 ?  299 VAL   A C   1 
ATOM   2120 O O   . VAL   A 1 319 ? 7.00565   -3.71550  8.65032   1.000 20.99629 ?  299 VAL   A O   1 
ATOM   2121 C CB  . VAL   A 1 319 ? 4.97732   -4.91078  6.36031   1.000 18.78574 ?  299 VAL   A CB  1 
ATOM   2122 C CG1 . VAL   A 1 319 ? 4.19044   -4.44933  7.56868   1.000 17.57052 ?  299 VAL   A CG1 1 
ATOM   2123 C CG2 . VAL   A 1 319 ? 4.29475   -4.44234  5.08615   1.000 21.99256 ?  299 VAL   A CG2 1 
ATOM   2124 N N   . TRP   A 1 320 ? 7.69790   -5.74904  7.97722   1.000 27.27283 ?  300 TRP   A N   1 
ATOM   2125 C CA  . TRP   A 1 320 ? 8.48489   -5.95971  9.18787   1.000 27.08531 ?  300 TRP   A CA  1 
ATOM   2126 C C   . TRP   A 1 320 ? 9.60901   -4.93824  9.29237   1.000 28.09808 ?  300 TRP   A C   1 
ATOM   2127 O O   . TRP   A 1 320 ? 9.78762   -4.29329  10.33299  1.000 25.94558 ?  300 TRP   A O   1 
ATOM   2128 C CB  . TRP   A 1 320 ? 9.05822   -7.37754  9.21168   1.000 26.58624 ?  300 TRP   A CB  1 
ATOM   2129 C CG  . TRP   A 1 320 ? 10.23505  -7.49128  10.12878  1.000 32.83466 ?  300 TRP   A CG  1 
ATOM   2130 C CD1 . TRP   A 1 320 ? 11.54905  -7.26670  9.82025   1.000 36.21012 ?  300 TRP   A CD1 1 
ATOM   2131 C CD2 . TRP   A 1 320 ? 10.20135  -7.81440  11.51846  1.000 31.32408 ?  300 TRP   A CD2 1 
ATOM   2132 N NE1 . TRP   A 1 320 ? 12.33335  -7.44628  10.93141  1.000 37.38185 ?  300 TRP   A NE1 1 
ATOM   2133 C CE2 . TRP   A 1 320 ? 11.52986  -7.78447  11.98784  1.000 35.15523 ?  300 TRP   A CE2 1 
ATOM   2134 C CE3 . TRP   A 1 320 ? 9.17780   -8.13685  12.41095  1.000 29.01976 ?  300 TRP   A CE3 1 
ATOM   2135 C CZ2 . TRP   A 1 320 ? 11.85810  -8.06458  13.30870  1.000 38.51911 ?  300 TRP   A CZ2 1 
ATOM   2136 C CZ3 . TRP   A 1 320 ? 9.50610   -8.41641  13.71442  1.000 31.96138 ?  300 TRP   A CZ3 1 
ATOM   2137 C CH2 . TRP   A 1 320 ? 10.83280  -8.37251  14.15584  1.000 41.67123 ?  300 TRP   A CH2 1 
ATOM   2138 N N   . GLU   A 1 321 ? 10.39371  -4.79937  8.22110   1.000 29.88700 ?  301 GLU   A N   1 
ATOM   2139 C CA  . GLU   A 1 321 ? 11.53415  -3.88904  8.23365   1.000 34.19398 ?  301 GLU   A CA  1 
ATOM   2140 C C   . GLU   A 1 321 ? 11.09972  -2.46323  8.54406   1.000 31.25785 ?  301 GLU   A C   1 
ATOM   2141 O O   . GLU   A 1 321 ? 11.81459  -1.72028  9.22742   1.000 28.54021 ?  301 GLU   A O   1 
ATOM   2142 C CB  . GLU   A 1 321 ? 12.25249  -3.94408  6.88534   1.000 30.78559 ?  301 GLU   A CB  1 
ATOM   2143 C CG  . GLU   A 1 321 ? 13.48261  -4.83463  6.85762   1.000 34.76205 ?  301 GLU   A CG  1 
ATOM   2144 C CD  . GLU   A 1 321 ? 14.50634  -4.45294  7.90502   1.000 42.13320 ?  301 GLU   A CD  1 
ATOM   2145 O OE1 . GLU   A 1 321 ? 14.89918  -3.26738  7.94738   1.000 44.92644 ?  301 GLU   A OE1 1 
ATOM   2146 O OE2 . GLU   A 1 321 ? 14.92175  -5.33696  8.68177   1.000 48.48262 ?  301 GLU   A OE2 1 
ATOM   2147 N N   . SER   A 1 322 ? 9.92221   -2.06849  8.05983   1.000 26.25645 ?  302 SER   A N   1 
ATOM   2148 C CA  . SER   A 1 322 ? 9.45924   -0.69972  8.24695   1.000 26.43400 ?  302 SER   A CA  1 
ATOM   2149 C C   . SER   A 1 322 ? 8.92198   -0.47329  9.65462   1.000 23.67384 ?  302 SER   A C   1 
ATOM   2150 O O   . SER   A 1 322 ? 9.16933   0.57700   10.25396  1.000 29.00750 ?  302 SER   A O   1 
ATOM   2151 C CB  . SER   A 1 322 ? 8.38999   -0.36798  7.20715   1.000 27.03744 ?  302 SER   A CB  1 
ATOM   2152 O OG  . SER   A 1 322 ? 7.45797   0.57158   7.71252   1.000 26.29060 ?  302 SER   A OG  1 
ATOM   2153 N N   . THR   A 1 323 ? 8.18707   -1.44022  10.20207  1.000 23.44916 ?  303 THR   A N   1 
ATOM   2154 C CA  . THR   A 1 323 ? 7.62483   -1.25353  11.53498  1.000 23.01802 ?  303 THR   A CA  1 
ATOM   2155 C C   . THR   A 1 323 ? 8.70932   -1.31585  12.60508  1.000 26.46641 ?  303 THR   A C   1 
ATOM   2156 O O   . THR   A 1 323 ? 8.67898   -0.55018  13.57661  1.000 21.12573 ?  303 THR   A O   1 
ATOM   2157 C CB  . THR   A 1 323 ? 6.54046   -2.30013  11.79533  1.000 21.01314 ?  303 THR   A CB  1 
ATOM   2158 O OG1 . THR   A 1 323 ? 5.43210   -2.06487  10.91876  1.000 19.93163 ?  303 THR   A OG1 1 
ATOM   2159 C CG2 . THR   A 1 323 ? 6.05141   -2.22115  13.23255  1.000 21.98853 ?  303 THR   A CG2 1 
ATOM   2160 N N   . PHE   A 1 324 ? 9.69244   -2.19571  12.42852  1.000 24.44831 ?  304 PHE   A N   1 
ATOM   2161 C CA  . PHE   A 1 324 ? 10.67688  -2.45115  13.47183  1.000 25.58840 ?  304 PHE   A CA  1 
ATOM   2162 C C   . PHE   A 1 324 ? 11.94823  -1.62507  13.32838  1.000 31.87254 ?  304 PHE   A C   1 
ATOM   2163 O O   . PHE   A 1 324 ? 12.57035  -1.29137  14.34256  1.000 32.27065 ?  304 PHE   A O   1 
ATOM   2164 C CB  . PHE   A 1 324 ? 11.03186  -3.93994  13.49028  1.000 30.07916 ?  304 PHE   A CB  1 
ATOM   2165 C CG  . PHE   A 1 324 ? 10.32048  -4.71422  14.55903  1.000 32.54777 ?  304 PHE   A CG  1 
ATOM   2166 C CD1 . PHE   A 1 324 ? 9.01606   -5.14074  14.37050  1.000 32.27490 ?  304 PHE   A CD1 1 
ATOM   2167 C CD2 . PHE   A 1 324 ? 10.95910  -5.02748  15.74713  1.000 30.57133 ?  304 PHE   A CD2 1 
ATOM   2168 C CE1 . PHE   A 1 324 ? 8.35676   -5.85021  15.35512  1.000 31.80799 ?  304 PHE   A CE1 1 
ATOM   2169 C CE2 . PHE   A 1 324 ? 10.30770  -5.74211  16.73249  1.000 32.28369 ?  304 PHE   A CE2 1 
ATOM   2170 C CZ  . PHE   A 1 324 ? 9.00427   -6.15597  16.53439  1.000 30.42409 ?  304 PHE   A CZ  1 
ATOM   2171 N N   . SER   A 1 325 ? 12.34654  -1.26825  12.10704  1.000 30.80843 ?  305 SER   A N   1 
ATOM   2172 C CA  . SER   A 1 325 ? 13.64786  -0.63765  11.91747  1.000 35.14949 ?  305 SER   A CA  1 
ATOM   2173 C C   . SER   A 1 325 ? 13.58543  0.65503   11.11306  1.000 26.99967 ?  305 SER   A C   1 
ATOM   2174 O O   . SER   A 1 325 ? 13.71236  1.74882   11.67421  1.000 29.46972 ?  305 SER   A O   1 
ATOM   2175 C CB  . SER   A 1 325 ? 14.60849  -1.61570  11.23703  1.000 39.33128 ?  305 SER   A CB  1 
ATOM   2176 O OG  . SER   A 1 325 ? 14.38926  -2.94262  11.68069  1.000 49.68015 ?  305 SER   A OG  1 
ATOM   2177 N N   . SER   A 1 326 ? 13.40116  0.53708   9.79640   1.000 31.47106 ?  306 SER   A N   1 
ATOM   2178 C CA  . SER   A 1 326 ? 13.64872  1.66444   8.90372   1.000 29.91560 ?  306 SER   A CA  1 
ATOM   2179 C C   . SER   A 1 326 ? 12.58365  2.74991   8.99236   1.000 28.15052 ?  306 SER   A C   1 
ATOM   2180 O O   . SER   A 1 326 ? 12.87176  3.90265   8.65324   1.000 33.35339 ?  306 SER   A O   1 
ATOM   2181 C CB  . SER   A 1 326 ? 13.75820  1.17253   7.46112   1.000 29.24621 ?  306 SER   A CB  1 
ATOM   2182 O OG  . SER   A 1 326 ? 12.47687  1.03085   6.87161   1.000 30.21370 ?  306 SER   A OG  1 
ATOM   2183 N N   . LYS   A 1 327 ? 11.36891  2.41287   9.42195   1.000 26.92481 ?  307 LYS   A N   1 
ATOM   2184 C CA  . LYS   A 1 327 ? 10.22904  3.32589   9.48387   1.000 27.73282 ?  307 LYS   A CA  1 
ATOM   2185 C C   . LYS   A 1 327 ? 9.86159   3.91334   8.12454   1.000 25.51309 ?  307 LYS   A C   1 
ATOM   2186 O O   . LYS   A 1 327 ? 9.10088   4.88700   8.06132   1.000 24.96849 ?  307 LYS   A O   1 
ATOM   2187 C CB  . LYS   A 1 327 ? 10.46120  4.45363   10.50008  1.000 25.86147 ?  307 LYS   A CB  1 
ATOM   2188 C CG  . LYS   A 1 327 ? 9.92799   4.14428   11.89392  1.000 25.13143 ?  307 LYS   A CG  1 
ATOM   2189 C CD  . LYS   A 1 327 ? 10.80616  3.13426   12.61902  1.000 25.19229 ?  307 LYS   A CD  1 
ATOM   2190 C CE  . LYS   A 1 327 ? 10.32910  2.90400   14.04592  1.000 27.01932 ?  307 LYS   A CE  1 
ATOM   2191 N NZ  . LYS   A 1 327 ? 9.13508   2.01341   14.10659  1.000 17.76043 ?  307 LYS   A NZ  1 
ATOM   2192 N N   . GLU   A 1 328 ? 10.37040  3.34648   7.03835   1.000 25.41029 ?  308 GLU   A N   1 
ATOM   2193 C CA  . GLU   A 1 328 ? 9.99526   3.79739   5.70369   1.000 28.09998 ?  308 GLU   A CA  1 
ATOM   2194 C C   . GLU   A 1 328 ? 8.54419   3.42105   5.43695   1.000 27.84139 ?  308 GLU   A C   1 
ATOM   2195 O O   . GLU   A 1 328 ? 8.19404   2.23844   5.53678   1.000 27.28060 ?  308 GLU   A O   1 
ATOM   2196 C CB  . GLU   A 1 328 ? 10.91195  3.18058   4.65265   1.000 30.96225 ?  308 GLU   A CB  1 
ATOM   2197 N N   . PRO   A 1 329 ? 7.67657   4.37361   5.10069   1.000 23.88451 ?  309 PRO   A N   1 
ATOM   2198 C CA  . PRO   A 1 329 ? 6.24379   4.06828   5.00752   1.000 28.35829 ?  309 PRO   A CA  1 
ATOM   2199 C C   . PRO   A 1 329 ? 5.93844   3.02359   3.94353   1.000 27.22796 ?  309 PRO   A C   1 
ATOM   2200 O O   . PRO   A 1 329 ? 6.49287   3.04307   2.84240   1.000 27.40083 ?  309 PRO   A O   1 
ATOM   2201 C CB  . PRO   A 1 329 ? 5.61751   5.42083   4.65118   1.000 27.30482 ?  309 PRO   A CB  1 
ATOM   2202 C CG  . PRO   A 1 329 ? 6.58845   6.43231   5.14096   1.000 26.74313 ?  309 PRO   A CG  1 
ATOM   2203 C CD  . PRO   A 1 329 ? 7.94755   5.81605   4.98115   1.000 24.32271 ?  309 PRO   A CD  1 
ATOM   2204 N N   . VAL   A 1 330 ? 5.04835   2.09965   4.29602   1.000 24.53662 ?  310 VAL   A N   1 
ATOM   2205 C CA  . VAL   A 1 330 ? 4.44262   1.16240   3.35860   1.000 23.62100 ?  310 VAL   A CA  1 
ATOM   2206 C C   . VAL   A 1 330 ? 2.94260   1.41255   3.37510   1.000 26.45506 ?  310 VAL   A C   1 
ATOM   2207 O O   . VAL   A 1 330 ? 2.31285   1.35419   4.43762   1.000 27.07767 ?  310 VAL   A O   1 
ATOM   2208 C CB  . VAL   A 1 330 ? 4.75834   -0.30071  3.71872   1.000 25.44401 ?  310 VAL   A CB  1 
ATOM   2209 C CG1 . VAL   A 1 330 ? 3.94903   -1.24561  2.84253   1.000 18.87188 ?  310 VAL   A CG1 1 
ATOM   2210 C CG2 . VAL   A 1 330 ? 6.24729   -0.57596  3.57683   1.000 23.61930 ?  310 VAL   A CG2 1 
ATOM   2211 N N   . TRP   A 1 331 ? 2.37376   1.69188   2.20628   1.000 23.38983 ?  311 TRP   A N   1 
ATOM   2212 C CA  . TRP   A 1 331 ? 0.99559   2.15229   2.09497   1.000 26.09876 ?  311 TRP   A CA  1 
ATOM   2213 C C   . TRP   A 1 331 ? 0.12359   1.04222   1.52485   1.000 27.35023 ?  311 TRP   A C   1 
ATOM   2214 O O   . TRP   A 1 331 ? 0.36286   0.57004   0.40809   1.000 25.61223 ?  311 TRP   A O   1 
ATOM   2215 C CB  . TRP   A 1 331 ? 0.91585   3.40445   1.22322   1.000 29.68721 ?  311 TRP   A CB  1 
ATOM   2216 C CG  . TRP   A 1 331 ? 1.66234   4.56015   1.80314   1.000 29.66049 ?  311 TRP   A CG  1 
ATOM   2217 C CD1 . TRP   A 1 331 ? 2.94085   4.93963   1.51411   1.000 30.34129 ?  311 TRP   A CD1 1 
ATOM   2218 C CD2 . TRP   A 1 331 ? 1.18416   5.47937   2.78995   1.000 29.85527 ?  311 TRP   A CD2 1 
ATOM   2219 N NE1 . TRP   A 1 331 ? 3.28499   6.04488   2.25291   1.000 28.84149 ?  311 TRP   A NE1 1 
ATOM   2220 C CE2 . TRP   A 1 331 ? 2.22348   6.39594   3.04512   1.000 30.00903 ?  311 TRP   A CE2 1 
ATOM   2221 C CE3 . TRP   A 1 331 ? -0.02388  5.61952   3.47958   1.000 33.55214 ?  311 TRP   A CE3 1 
ATOM   2222 C CZ2 . TRP   A 1 331 ? 2.09122   7.43766   3.96057   1.000 22.17773 ?  311 TRP   A CZ2 1 
ATOM   2223 C CZ3 . TRP   A 1 331 ? -0.15323  6.65360   4.38698   1.000 30.37513 ?  311 TRP   A CZ3 1 
ATOM   2224 C CH2 . TRP   A 1 331 ? 0.89778   7.54912   4.61960   1.000 28.91806 ?  311 TRP   A CH2 1 
ATOM   2225 N N   . LEU   A 1 332 ? -0.88960  0.64052   2.28874   1.000 22.33903 ?  312 LEU   A N   1 
ATOM   2226 C CA  . LEU   A 1 332 ? -1.84216  -0.37411  1.85859   1.000 24.26490 ?  312 LEU   A CA  1 
ATOM   2227 C C   . LEU   A 1 332 ? -3.07048  0.30328   1.26339   1.000 25.85530 ?  312 LEU   A C   1 
ATOM   2228 O O   . LEU   A 1 332 ? -3.69876  1.14407   1.91532   1.000 26.09568 ?  312 LEU   A O   1 
ATOM   2229 C CB  . LEU   A 1 332 ? -2.24752  -1.26966  3.02821   1.000 22.54416 ?  312 LEU   A CB  1 
ATOM   2230 C CG  . LEU   A 1 332 ? -3.48537  -2.13742  2.78303   1.000 23.27887 ?  312 LEU   A CG  1 
ATOM   2231 C CD1 . LEU   A 1 332 ? -3.23136  -3.15647  1.67760   1.000 23.71761 ?  312 LEU   A CD1 1 
ATOM   2232 C CD2 . LEU   A 1 332 ? -3.93320  -2.82377  4.06338   1.000 19.68057 ?  312 LEU   A CD2 1 
ATOM   2233 N N   . THR   A 1 333 ? -3.41285  -0.06639  0.03382   1.000 22.22315 ?  313 THR   A N   1 
ATOM   2234 C CA  . THR   A 1 333 ? -4.62920  0.39398   -0.62051  1.000 21.94342 ?  313 THR   A CA  1 
ATOM   2235 C C   . THR   A 1 333 ? -5.57790  -0.78406  -0.78808  1.000 24.10843 ?  313 THR   A C   1 
ATOM   2236 O O   . THR   A 1 333 ? -5.18973  -1.82703  -1.32430  1.000 29.74472 ?  313 THR   A O   1 
ATOM   2237 C CB  . THR   A 1 333 ? -4.32344  1.02560   -1.98154  1.000 21.55576 ?  313 THR   A CB  1 
ATOM   2238 O OG1 . THR   A 1 333 ? -3.65072  2.27666   -1.79171  1.000 22.29387 ?  313 THR   A OG1 1 
ATOM   2239 C CG2 . THR   A 1 333 ? -5.60842  1.25972   -2.76488  1.000 29.19330 ?  313 THR   A CG2 1 
ATOM   2240 N N   . VAL   A 1 334 ? -6.80990  -0.62339  -0.31385  1.000 23.71802 ?  314 VAL   A N   1 
ATOM   2241 C CA  . VAL   A 1 334 ? -7.86095  -1.61902  -0.48197  1.000 22.22052 ?  314 VAL   A CA  1 
ATOM   2242 C C   . VAL   A 1 334 ? -8.96282  -0.99012  -1.32098  1.000 23.89091 ?  314 VAL   A C   1 
ATOM   2243 O O   . VAL   A 1 334 ? -9.40007  0.13080   -1.03672  1.000 24.60481 ?  314 VAL   A O   1 
ATOM   2244 C CB  . VAL   A 1 334 ? -8.40923  -2.11062  0.87061   1.000 20.52652 ?  314 VAL   A CB  1 
ATOM   2245 C CG1 . VAL   A 1 334 ? -9.22221  -3.38307  0.68115   1.000 22.71611 ?  314 VAL   A CG1 1 
ATOM   2246 C CG2 . VAL   A 1 334 ? -7.27258  -2.33805  1.86004   1.000 28.30354 ?  314 VAL   A CG2 1 
ATOM   2247 N N   . GLU   A 1 335 ? -9.40156  -1.70255  -2.35663  1.000 22.17942 ?  315 GLU   A N   1 
ATOM   2248 C CA  . GLU   A 1 335 ? -10.38387 -1.15939  -3.28269  1.000 26.52450 ?  315 GLU   A CA  1 
ATOM   2249 C C   . GLU   A 1 335 ? -11.27077 -2.27804  -3.80730  1.000 26.78936 ?  315 GLU   A C   1 
ATOM   2250 O O   . GLU   A 1 335 ? -10.87356 -3.44602  -3.83685  1.000 24.60092 ?  315 GLU   A O   1 
ATOM   2251 C CB  . GLU   A 1 335 ? -9.70985  -0.43327  -4.45300  1.000 25.07072 ?  315 GLU   A CB  1 
ATOM   2252 C CG  . GLU   A 1 335 ? -8.95691  -1.35240  -5.40137  1.000 32.93517 ?  315 GLU   A CG  1 
ATOM   2253 C CD  . GLU   A 1 335 ? -8.01098  -0.59888  -6.31419  1.000 36.40501 ?  315 GLU   A CD  1 
ATOM   2254 O OE1 . GLU   A 1 335 ? -8.49561  0.08555   -7.23988  1.000 38.93938 ?  315 GLU   A OE1 1 
ATOM   2255 O OE2 . GLU   A 1 335 ? -6.78307  -0.68870  -6.10441  1.000 38.07177 ?  315 GLU   A OE2 1 
ATOM   2256 N N   . ARG   A 1 336 ? -12.47775 -1.90321  -4.22134  1.000 24.27225 ?  316 ARG   A N   1 
ATOM   2257 C CA  . ARG   A 1 336 ? -13.40859 -2.84453  -4.82286  1.000 28.65353 ?  316 ARG   A CA  1 
ATOM   2258 C C   . ARG   A 1 336 ? -13.02191 -3.11854  -6.27157  1.000 28.88657 ?  316 ARG   A C   1 
ATOM   2259 O O   . ARG   A 1 336 ? -12.50001 -2.24740  -6.97321  1.000 29.54318 ?  316 ARG   A O   1 
ATOM   2260 C CB  . ARG   A 1 336 ? -14.83742 -2.29984  -4.75338  1.000 26.18706 ?  316 ARG   A CB  1 
ATOM   2261 C CG  . ARG   A 1 336 ? -15.90181 -3.24094  -5.29821  1.000 34.73681 ?  316 ARG   A CG  1 
ATOM   2262 C CD  . ARG   A 1 336 ? -16.52632 -4.07770  -4.19663  1.000 29.32211 ?  316 ARG   A CD  1 
ATOM   2263 N NE  . ARG   A 1 336 ? -17.42397 -3.29131  -3.35985  1.000 37.84013 ?  316 ARG   A NE  1 
ATOM   2264 C CZ  . ARG   A 1 336 ? -18.71646 -3.54303  -3.20401  1.000 35.14524 ?  316 ARG   A CZ  1 
ATOM   2265 N NH1 . ARG   A 1 336 ? -19.30398 -4.55347  -3.82384  1.000 37.08580 ?  316 ARG   A NH1 1 
ATOM   2266 N NH2 . ARG   A 1 336 ? -19.43884 -2.75832  -2.40954  1.000 35.48000 ?  316 ARG   A NH2 1 
ATOM   2267 N N   . LEU   A 1 337 ? -13.27196 -4.34662  -6.71378  1.000 25.85517 ?  317 LEU   A N   1 
ATOM   2268 C CA  . LEU   A 1 337 ? -13.02000 -4.71199  -8.10265  1.000 34.44483 ?  317 LEU   A CA  1 
ATOM   2269 C C   . LEU   A 1 337 ? -14.32456 -4.87159  -8.87626  1.000 34.85352 ?  317 LEU   A C   1 
ATOM   2270 O O   . LEU   A 1 337 ? -15.39368 -5.01833  -8.28479  1.000 37.03180 ?  317 LEU   A O   1 
ATOM   2271 C CB  . LEU   A 1 337 ? -12.20369 -6.00160  -8.18459  1.000 32.81772 ?  317 LEU   A CB  1 
ATOM   2272 C CG  . LEU   A 1 337 ? -10.68572 -5.84273  -8.10631  1.000 29.41585 ?  317 LEU   A CG  1 
ATOM   2273 C CD1 . LEU   A 1 337 ? -10.03852 -7.13618  -7.63392  1.000 25.51241 ?  317 LEU   A CD1 1 
ATOM   2274 C CD2 . LEU   A 1 337 ? -10.12915 -5.40763  -9.45300  1.000 38.95315 ?  317 LEU   A CD2 1 
ATOM   2275 N N   . SER   B 1 22  ? -13.67440 -11.60908 52.92621  1.000 43.91387 ?  2   SER   B N   1 
ATOM   2276 C CA  . SER   B 1 22  ? -13.00961 -11.28627 51.66930  1.000 43.76101 ?  2   SER   B CA  1 
ATOM   2277 C C   . SER   B 1 22  ? -13.58270 -12.11490 50.52266  1.000 41.87294 ?  2   SER   B C   1 
ATOM   2278 O O   . SER   B 1 22  ? -13.68631 -13.33796 50.61840  1.000 36.53484 ?  2   SER   B O   1 
ATOM   2279 C CB  . SER   B 1 22  ? -11.50109 -11.51228 51.78728  1.000 39.13028 ?  2   SER   B CB  1 
ATOM   2280 O OG  . SER   B 1 22  ? -11.21523 -12.82352 52.24097  1.000 46.09877 ?  2   SER   B OG  1 
ATOM   2281 N N   . ALA   B 1 23  ? -13.95218 -11.43557 49.43421  1.000 37.40857 ?  3   ALA   B N   1 
ATOM   2282 C CA  . ALA   B 1 23  ? -14.58751 -12.12197 48.31371  1.000 40.53504 ?  3   ALA   B CA  1 
ATOM   2283 C C   . ALA   B 1 23  ? -13.60073 -13.01619 47.57280  1.000 41.10679 ?  3   ALA   B C   1 
ATOM   2284 O O   . ALA   B 1 23  ? -13.95273 -14.12637 47.15735  1.000 44.21821 ?  3   ALA   B O   1 
ATOM   2285 C CB  . ALA   B 1 23  ? -15.20971 -11.10267 47.35992  1.000 37.82453 ?  3   ALA   B CB  1 
ATOM   2286 N N   . LEU   B 1 24  ? -12.36168 -12.55211 47.39584  1.000 31.17646 ?  4   LEU   B N   1 
ATOM   2287 C CA  . LEU   B 1 24  ? -11.32360 -13.28038 46.66914  1.000 25.33065 ?  4   LEU   B CA  1 
ATOM   2288 C C   . LEU   B 1 24  ? -10.15518 -13.49903 47.62405  1.000 26.88239 ?  4   LEU   B C   1 
ATOM   2289 O O   . LEU   B 1 24  ? -9.15299  -12.76967 47.57393  1.000 24.24259 ?  4   LEU   B O   1 
ATOM   2290 C CB  . LEU   B 1 24  ? -10.89686 -12.51753 45.41661  1.000 25.83886 ?  4   LEU   B CB  1 
ATOM   2291 C CG  . LEU   B 1 24  ? -12.07299 -11.99988 44.58149  1.000 28.18015 ?  4   LEU   B CG  1 
ATOM   2292 C CD1 . LEU   B 1 24  ? -11.62543 -10.95730 43.56749  1.000 24.60315 ?  4   LEU   B CD1 1 
ATOM   2293 C CD2 . LEU   B 1 24  ? -12.79886 -13.15093 43.89560  1.000 26.95927 ?  4   LEU   B CD2 1 
ATOM   2294 N N   . PRO   B 1 25  ? -10.24603 -14.50047 48.50529  1.000 28.17305 ?  5   PRO   B N   1 
ATOM   2295 C CA  . PRO   B 1 25  ? -9.23999  -14.62512 49.57346  1.000 27.28343 ?  5   PRO   B CA  1 
ATOM   2296 C C   . PRO   B 1 25  ? -7.84805  -14.97802 49.07861  1.000 23.05925 ?  5   PRO   B C   1 
ATOM   2297 O O   . PRO   B 1 25  ? -6.86740  -14.58424 49.72151  1.000 29.04535 ?  5   PRO   B O   1 
ATOM   2298 C CB  . PRO   B 1 25  ? -9.81511  -15.73096 50.46937  1.000 27.59208 ?  5   PRO   B CB  1 
ATOM   2299 C CG  . PRO   B 1 25  ? -10.71423 -16.51510 49.57086  1.000 26.97510 ?  5   PRO   B CG  1 
ATOM   2300 C CD  . PRO   B 1 25  ? -11.29980 -15.52410 48.61001  1.000 33.64823 ?  5   PRO   B CD  1 
ATOM   2301 N N   . GLU   B 1 26  ? -7.72129  -15.71553 47.97245  1.000 22.68095 ?  6   GLU   B N   1 
ATOM   2302 C CA  . GLU   B 1 26  ? -6.38996  -16.01939 47.45577  1.000 24.76847 ?  6   GLU   B CA  1 
ATOM   2303 C C   . GLU   B 1 26  ? -5.67646  -14.75495 46.99851  1.000 27.28310 ?  6   GLU   B C   1 
ATOM   2304 O O   . GLU   B 1 26  ? -4.45450  -14.63520 47.15071  1.000 25.97140 ?  6   GLU   B O   1 
ATOM   2305 C CB  . GLU   B 1 26  ? -6.47333  -17.02247 46.30772  1.000 26.12693 ?  6   GLU   B CB  1 
ATOM   2306 C CG  . GLU   B 1 26  ? -5.11874  -17.36730 45.70345  1.000 25.34566 ?  6   GLU   B CG  1 
ATOM   2307 C CD  . GLU   B 1 26  ? -5.21496  -18.38280 44.58511  1.000 28.32109 ?  6   GLU   B CD  1 
ATOM   2308 O OE1 . GLU   B 1 26  ? -6.21956  -18.35635 43.84459  1.000 26.92186 ?  6   GLU   B OE1 1 
ATOM   2309 O OE2 . GLU   B 1 26  ? -4.28378  -19.20359 44.44192  1.000 27.59288 ?  6   GLU   B OE2 1 
ATOM   2310 N N   . LEU   B 1 27  ? -6.41915  -13.80494 46.42596  1.000 24.57757 ?  7   LEU   B N   1 
ATOM   2311 C CA  . LEU   B 1 27  ? -5.81920  -12.52194 46.08136  1.000 23.54576 ?  7   LEU   B CA  1 
ATOM   2312 C C   . LEU   B 1 27  ? -5.26353  -11.83563 47.32114  1.000 23.38525 ?  7   LEU   B C   1 
ATOM   2313 O O   . LEU   B 1 27  ? -4.15494  -11.29047 47.29048  1.000 22.22647 ?  7   LEU   B O   1 
ATOM   2314 C CB  . LEU   B 1 27  ? -6.84234  -11.63012 45.37715  1.000 21.12681 ?  7   LEU   B CB  1 
ATOM   2315 C CG  . LEU   B 1 27  ? -7.28584  -12.08168 43.98255  1.000 22.63377 ?  7   LEU   B CG  1 
ATOM   2316 C CD1 . LEU   B 1 27  ? -7.98781  -10.95135 43.24390  1.000 19.68280 ?  7   LEU   B CD1 1 
ATOM   2317 C CD2 . LEU   B 1 27  ? -6.10023  -12.59554 43.17709  1.000 25.81635 ?  7   LEU   B CD2 1 
ATOM   2318 N N   . ARG   B 1 28  ? -6.01258  -11.87577 48.42874  1.000 24.94081 ?  8   ARG   B N   1 
ATOM   2319 C CA  . ARG   B 1 28  ? -5.52213  -11.32483 49.68956  1.000 26.81309 ?  8   ARG   B CA  1 
ATOM   2320 C C   . ARG   B 1 28  ? -4.20725  -11.97439 50.10318  1.000 26.98950 ?  8   ARG   B C   1 
ATOM   2321 O O   . ARG   B 1 28  ? -3.29431  -11.29246 50.58363  1.000 25.86801 ?  8   ARG   B O   1 
ATOM   2322 C CB  . ARG   B 1 28  ? -6.57111  -11.50865 50.78741  1.000 21.49637 ?  8   ARG   B CB  1 
ATOM   2323 C CG  . ARG   B 1 28  ? -7.74931  -10.54911 50.71905  1.000 30.16369 ?  8   ARG   B CG  1 
ATOM   2324 C CD  . ARG   B 1 28  ? -7.29552  -9.11773  50.49815  1.000 35.31300 ?  8   ARG   B CD  1 
ATOM   2325 N NE  . ARG   B 1 28  ? -8.42150  -8.19727  50.39275  1.000 43.48607 ?  8   ARG   B NE  1 
ATOM   2326 C CZ  . ARG   B 1 28  ? -8.31287  -6.87632  50.43162  1.000 43.93587 ?  8   ARG   B CZ  1 
ATOM   2327 N NH1 . ARG   B 1 28  ? -7.13869  -6.28356  50.57440  1.000 43.41752 ?  8   ARG   B NH1 1 
ATOM   2328 N NH2 . ARG   B 1 28  ? -9.40937  -6.13131  50.32387  1.000 39.96720 ?  8   ARG   B NH2 1 
ATOM   2329 N N   . GLU   B 1 29  ? -4.09501  -13.29405 49.93160  1.000 29.46132 ?  9   GLU   B N   1 
ATOM   2330 C CA  . GLU   B 1 29  ? -2.83684  -13.97525 50.21999  1.000 24.14461 ?  9   GLU   B CA  1 
ATOM   2331 C C   . GLU   B 1 29  ? -1.71920  -13.45474 49.32537  1.000 27.57838 ?  9   GLU   B C   1 
ATOM   2332 O O   . GLU   B 1 29  ? -0.60341  -13.19238 49.79092  1.000 25.98735 ?  9   GLU   B O   1 
ATOM   2333 C CB  . GLU   B 1 29  ? -3.00407  -15.48492 50.04225  1.000 29.11828 ?  9   GLU   B CB  1 
ATOM   2334 C CG  . GLU   B 1 29  ? -3.76435  -16.17927 51.15813  1.000 36.95831 ?  9   GLU   B CG  1 
ATOM   2335 C CD  . GLU   B 1 29  ? -3.81996  -17.68096 50.96057  1.000 42.75281 ?  9   GLU   B CD  1 
ATOM   2336 O OE1 . GLU   B 1 29  ? -3.29649  -18.16202 49.93307  1.000 40.17474 ?  9   GLU   B OE1 1 
ATOM   2337 O OE2 . GLU   B 1 29  ? -4.38176  -18.38021 51.82991  1.000 45.52388 ?  9   GLU   B OE2 1 
ATOM   2338 N N   . LEU   B 1 30  ? -2.00469  -13.29988 48.02954  1.000 23.69969 ?  10  LEU   B N   1 
ATOM   2339 C CA  . LEU   B 1 30  ? -0.99550  -12.80153 47.10241  1.000 25.48748 ?  10  LEU   B CA  1 
ATOM   2340 C C   . LEU   B 1 30  ? -0.62148  -11.35619 47.39840  1.000 26.30899 ?  10  LEU   B C   1 
ATOM   2341 O O   . LEU   B 1 30  ? 0.53045   -10.96601 47.18074  1.000 28.77941 ?  10  LEU   B O   1 
ATOM   2342 C CB  . LEU   B 1 30  ? -1.48971  -12.94273 45.66218  1.000 26.75746 ?  10  LEU   B CB  1 
ATOM   2343 C CG  . LEU   B 1 30  ? -1.63691  -14.38517 45.16969  1.000 25.76267 ?  10  LEU   B CG  1 
ATOM   2344 C CD1 . LEU   B 1 30  ? -2.30605  -14.42165 43.80300  1.000 18.83053 ?  10  LEU   B CD1 1 
ATOM   2345 C CD2 . LEU   B 1 30  ? -0.28578  -15.08422 45.13917  1.000 23.45232 ?  10  LEU   B CD2 1 
ATOM   2346 N N   . ILE   B 1 31  ? -1.57204  -10.55275 47.88757  1.000 28.17835 ?  11  ILE   B N   1 
ATOM   2347 C CA  . ILE   B 1 31  ? -1.24852  -9.20292  48.35070  1.000 29.92133 ?  11  ILE   B CA  1 
ATOM   2348 C C   . ILE   B 1 31  ? -0.16750  -9.26240  49.42174  1.000 28.55398 ?  11  ILE   B C   1 
ATOM   2349 O O   . ILE   B 1 31  ? 0.89997   -8.65218  49.29205  1.000 31.06451 ?  11  ILE   B O   1 
ATOM   2350 C CB  . ILE   B 1 31  ? -2.50546  -8.48617  48.87583  1.000 27.80972 ?  11  ILE   B CB  1 
ATOM   2351 C CG1 . ILE   B 1 31  ? -3.57947  -8.37694  47.79691  1.000 31.23203 ?  11  ILE   B CG1 1 
ATOM   2352 C CG2 . ILE   B 1 31  ? -2.14582  -7.10577  49.40600  1.000 26.67340 ?  11  ILE   B CG2 1 
ATOM   2353 C CD1 . ILE   B 1 31  ? -3.40518  -7.19555  46.89977  1.000 29.55604 ?  11  ILE   B CD1 1 
ATOM   2354 N N   . ALA   B 1 32  ? -0.43126  -10.02190 50.48996  1.000 26.98432 ?  12  ALA   B N   1 
ATOM   2355 C CA  . ALA   B 1 32  ? 0.49339   -10.09529 51.61749  1.000 28.56789 ?  12  ALA   B CA  1 
ATOM   2356 C C   . ALA   B 1 32  ? 1.88272   -10.53821 51.17877  1.000 30.71888 ?  12  ALA   B C   1 
ATOM   2357 O O   . ALA   B 1 32  ? 2.89210   -9.99767  51.64581  1.000 33.02674 ?  12  ALA   B O   1 
ATOM   2358 C CB  . ALA   B 1 32  ? -0.06215  -11.04587 52.68079  1.000 25.37611 ?  12  ALA   B CB  1 
ATOM   2359 N N   . SER   B 1 33  ? 1.95489   -11.51400 50.27200  1.000 25.51146 ?  13  SER   B N   1 
ATOM   2360 C CA  . SER   B 1 33  ? 3.25228   -11.99004 49.80514  1.000 30.10603 ?  13  SER   B CA  1 
ATOM   2361 C C   . SER   B 1 33  ? 3.94934   -10.93906 48.94990  1.000 33.06345 ?  13  SER   B C   1 
ATOM   2362 O O   . SER   B 1 33  ? 5.14345   -10.67040 49.12732  1.000 28.46428 ?  13  SER   B O   1 
ATOM   2363 C CB  . SER   B 1 33  ? 3.08289   -13.29181 49.01957  1.000 32.91746 ?  13  SER   B CB  1 
ATOM   2364 O OG  . SER   B 1 33  ? 2.07046   -14.10660 49.58323  1.000 35.31210 ?  13  SER   B OG  1 
ATOM   2365 N N   . PHE   B 1 34  ? 3.21289   -10.32181 48.02445  1.000 27.65176 ?  14  PHE   B N   1 
ATOM   2366 C CA  . PHE   B 1 34  ? 3.82834   -9.47180  47.01332  1.000 27.57824 ?  14  PHE   B CA  1 
ATOM   2367 C C   . PHE   B 1 34  ? 4.28689   -8.12203  47.55113  1.000 27.88901 ?  14  PHE   B C   1 
ATOM   2368 O O   . PHE   B 1 34  ? 4.96775   -7.39296  46.82246  1.000 30.60514 ?  14  PHE   B O   1 
ATOM   2369 C CB  . PHE   B 1 34  ? 2.85930   -9.26063  45.84925  1.000 27.06491 ?  14  PHE   B CB  1 
ATOM   2370 C CG  . PHE   B 1 34  ? 2.67016   -10.47697 44.98718  1.000 26.83773 ?  14  PHE   B CG  1 
ATOM   2371 C CD1 . PHE   B 1 34  ? 3.50384   -11.57562 45.11925  1.000 23.21344 ?  14  PHE   B CD1 1 
ATOM   2372 C CD2 . PHE   B 1 34  ? 1.65378   -10.52286 44.04743  1.000 22.96835 ?  14  PHE   B CD2 1 
ATOM   2373 C CE1 . PHE   B 1 34  ? 3.32940   -12.69528 44.32885  1.000 27.32236 ?  14  PHE   B CE1 1 
ATOM   2374 C CE2 . PHE   B 1 34  ? 1.47470   -11.63971 43.25394  1.000 22.53682 ?  14  PHE   B CE2 1 
ATOM   2375 C CZ  . PHE   B 1 34  ? 2.31295   -12.72671 43.39473  1.000 21.93621 ?  14  PHE   B CZ  1 
ATOM   2376 N N   . VAL   B 1 35  ? 3.93587   -7.76443  48.78959  1.000 30.77646 ?  15  VAL   B N   1 
ATOM   2377 C CA  . VAL   B 1 35  ? 4.47115   -6.53516  49.37025  1.000 31.79061 ?  15  VAL   B CA  1 
ATOM   2378 C C   . VAL   B 1 35  ? 5.97852   -6.64047  49.54919  1.000 36.23156 ?  15  VAL   B C   1 
ATOM   2379 O O   . VAL   B 1 35  ? 6.70211   -5.64703  49.40350  1.000 29.54684 ?  15  VAL   B O   1 
ATOM   2380 C CB  . VAL   B 1 35  ? 3.77197   -6.21090  50.70656  1.000 35.81108 ?  15  VAL   B CB  1 
ATOM   2381 C CG1 . VAL   B 1 35  ? 4.24983   -4.87391  51.24325  1.000 34.09276 ?  15  VAL   B CG1 1 
ATOM   2382 C CG2 . VAL   B 1 35  ? 2.27027   -6.18172  50.52922  1.000 38.45128 ?  15  VAL   B CG2 1 
ATOM   2383 N N   . SER   B 1 36  ? 6.48010   -7.83987  49.85066  1.000 32.97390 ?  16  SER   B N   1 
ATOM   2384 C CA  . SER   B 1 36  ? 7.89334   -8.03767  50.13274  1.000 32.29749 ?  16  SER   B CA  1 
ATOM   2385 C C   . SER   B 1 36  ? 8.62843   -8.85953  49.08477  1.000 30.49613 ?  16  SER   B C   1 
ATOM   2386 O O   . SER   B 1 36  ? 9.85867   -8.77946  49.01931  1.000 33.94059 ?  16  SER   B O   1 
ATOM   2387 C CB  . SER   B 1 36  ? 8.07011   -8.71453  51.50037  1.000 31.39462 ?  16  SER   B CB  1 
ATOM   2388 O OG  . SER   B 1 36  ? 7.46332   -9.99534  51.51485  1.000 41.09533 ?  16  SER   B OG  1 
ATOM   2389 N N   . GLU   B 1 37  ? 7.92080   -9.63558  48.26835  1.000 31.08212 ?  17  GLU   B N   1 
ATOM   2390 C CA  . GLU   B 1 37  ? 8.54546   -10.53546 47.31004  1.000 30.55571 ?  17  GLU   B CA  1 
ATOM   2391 C C   . GLU   B 1 37  ? 8.09033   -10.20570 45.89565  1.000 29.21391 ?  17  GLU   B C   1 
ATOM   2392 O O   . GLU   B 1 37  ? 6.93187   -9.83928  45.67276  1.000 25.97819 ?  17  GLU   B O   1 
ATOM   2393 C CB  . GLU   B 1 37  ? 8.22018   -11.99539 47.63651  1.000 37.09033 ?  17  GLU   B CB  1 
ATOM   2394 C CG  . GLU   B 1 37  ? 9.38211   -12.75760 48.24827  1.000 50.59210 ?  17  GLU   B CG  1 
ATOM   2395 C CD  . GLU   B 1 37  ? 8.94143   -14.02607 48.94686  1.000 65.03222 ?  17  GLU   B CD  1 
ATOM   2396 O OE1 . GLU   B 1 37  ? 9.58123   -15.07704 48.73235  1.000 69.32516 ?  17  GLU   B OE1 1 
ATOM   2397 O OE2 . GLU   B 1 37  ? 7.95501   -13.97156 49.71117  1.000 67.81989 ?  17  GLU   B OE2 1 
ATOM   2398 N N   . GLU   B 1 38  ? 9.00973   -10.34197 44.94774  1.000 25.72041 ?  18  GLU   B N   1 
ATOM   2399 C CA  . GLU   B 1 38  ? 8.69211   -10.08591 43.54855  1.000 30.35762 ?  18  GLU   B CA  1 
ATOM   2400 C C   . GLU   B 1 38  ? 7.74416   -11.15958 43.02569  1.000 29.48016 ?  18  GLU   B C   1 
ATOM   2401 O O   . GLU   B 1 38  ? 8.00027   -12.35336 43.22326  1.000 32.75010 ?  18  GLU   B O   1 
ATOM   2402 C CB  . GLU   B 1 38  ? 9.97022   -10.05924 42.71143  1.000 32.44677 ?  18  GLU   B CB  1 
ATOM   2403 C CG  . GLU   B 1 38  ? 9.73844   -9.92026  41.21370  1.000 36.39913 ?  18  GLU   B CG  1 
ATOM   2404 C CD  . GLU   B 1 38  ? 11.02756  -9.98271  40.41564  1.000 35.93575 ?  18  GLU   B CD  1 
ATOM   2405 O OE1 . GLU   B 1 38  ? 12.08712  -10.26004 41.01616  1.000 33.06918 ?  18  GLU   B OE1 1 
ATOM   2406 O OE2 . GLU   B 1 38  ? 10.98180  -9.75573  39.18784  1.000 31.58064 ?  18  GLU   B OE2 1 
ATOM   2407 N N   . PRO   B 1 39  ? 6.65094   -10.78644 42.36629  1.000 30.99443 ?  19  PRO   B N   1 
ATOM   2408 C CA  . PRO   B 1 39  ? 5.75127   -11.78835 41.78670  1.000 28.61883 ?  19  PRO   B CA  1 
ATOM   2409 C C   . PRO   B 1 39  ? 6.45977   -12.58939 40.71082  1.000 27.60734 ?  19  PRO   B C   1 
ATOM   2410 O O   . PRO   B 1 39  ? 7.22424   -12.02825 39.91098  1.000 25.21359 ?  19  PRO   B O   1 
ATOM   2411 C CB  . PRO   B 1 39  ? 4.61131   -10.94390 41.19336  1.000 29.81949 ?  19  PRO   B CB  1 
ATOM   2412 C CG  . PRO   B 1 39  ? 4.70184   -9.62445  41.89394  1.000 27.90801 ?  19  PRO   B CG  1 
ATOM   2413 C CD  . PRO   B 1 39  ? 6.16162   -9.41667  42.14837  1.000 23.85814 ?  19  PRO   B CD  1 
ATOM   2414 N N   . PRO   B 1 40  ? 6.24183   -13.90647 40.66671  1.000 26.73516 ?  20  PRO   B N   1 
ATOM   2415 C CA  . PRO   B 1 40  ? 6.91393   -14.72348 39.64041  1.000 32.38209 ?  20  PRO   B CA  1 
ATOM   2416 C C   . PRO   B 1 40  ? 6.59215   -14.29253 38.22095  1.000 31.63191 ?  20  PRO   B C   1 
ATOM   2417 O O   . PRO   B 1 40  ? 7.43284   -14.46220 37.32896  1.000 29.37415 ?  20  PRO   B O   1 
ATOM   2418 C CB  . PRO   B 1 40  ? 6.41289   -16.14931 39.91660  1.000 35.74106 ?  20  PRO   B CB  1 
ATOM   2419 C CG  . PRO   B 1 40  ? 5.64734   -16.10462 41.18543  1.000 37.86349 ?  20  PRO   B CG  1 
ATOM   2420 C CD  . PRO   B 1 40  ? 5.49170   -14.70069 41.65358  1.000 29.22787 ?  20  PRO   B CD  1 
ATOM   2421 N N   . GLU   B 1 41  ? 5.40010   -13.74015 37.98326  1.000 27.87924 ?  21  GLU   B N   1 
ATOM   2422 C CA  . GLU   B 1 41  ? 5.05148   -13.27325 36.64515  1.000 30.90803 ?  21  GLU   B CA  1 
ATOM   2423 C C   . GLU   B 1 41  ? 5.98673   -12.15889 36.19686  1.000 24.17559 ?  21  GLU   B C   1 
ATOM   2424 O O   . GLU   B 1 41  ? 6.45792   -12.14922 35.05404  1.000 22.12891 ?  21  GLU   B O   1 
ATOM   2425 C CB  . GLU   B 1 41  ? 3.60000   -12.79351 36.61557  1.000 28.17664 ?  21  GLU   B CB  1 
ATOM   2426 C CG  . GLU   B 1 41  ? 2.59759   -13.77859 37.18593  1.000 35.14877 ?  21  GLU   B CG  1 
ATOM   2427 C CD  . GLU   B 1 41  ? 2.32445   -13.54226 38.65788  1.000 30.28127 ?  21  GLU   B CD  1 
ATOM   2428 O OE1 . GLU   B 1 41  ? 3.29558   -13.43207 39.43478  1.000 32.43992 ?  21  GLU   B OE1 1 
ATOM   2429 O OE2 . GLU   B 1 41  ? 1.13705   -13.45963 39.03682  1.000 33.13567 ?  21  GLU   B OE2 1 
ATOM   2430 N N   . ILE   B 1 42  ? 6.27189   -11.21154 37.09375  1.000 25.41113 ?  22  ILE   B N   1 
ATOM   2431 C CA  . ILE   B 1 42  ? 7.13567   -10.08626 36.74742  1.000 24.04359 ?  22  ILE   B CA  1 
ATOM   2432 C C   . ILE   B 1 42  ? 8.54076   -10.57240 36.41603  1.000 27.69668 ?  22  ILE   B C   1 
ATOM   2433 O O   . ILE   B 1 42  ? 9.16658   -10.10223 35.45775  1.000 27.55985 ?  22  ILE   B O   1 
ATOM   2434 C CB  . ILE   B 1 42  ? 7.14489   -9.05276  37.88931  1.000 21.72722 ?  22  ILE   B CB  1 
ATOM   2435 C CG1 . ILE   B 1 42  ? 5.75818   -8.42716  38.04562  1.000 27.72514 ?  22  ILE   B CG1 1 
ATOM   2436 C CG2 . ILE   B 1 42  ? 8.19635   -7.98053  37.63953  1.000 21.09274 ?  22  ILE   B CG2 1 
ATOM   2437 C CD1 . ILE   B 1 42  ? 5.22799   -7.79907  36.77475  1.000 24.25392 ?  22  ILE   B CD1 1 
ATOM   2438 N N   . ARG   B 1 43  ? 9.05557   -11.52716 37.19496  1.000 29.57621 ?  23  ARG   B N   1 
ATOM   2439 C CA  . ARG   B 1 43  ? 10.38942  -12.05704 36.92956  1.000 27.60748 ?  23  ARG   B CA  1 
ATOM   2440 C C   . ARG   B 1 43  ? 10.43646  -12.80597 35.60387  1.000 27.46452 ?  23  ARG   B C   1 
ATOM   2441 O O   . ARG   B 1 43  ? 11.44589  -12.75355 34.89207  1.000 31.70570 ?  23  ARG   B O   1 
ATOM   2442 C CB  . ARG   B 1 43  ? 10.83152  -12.96909 38.07378  1.000 36.03948 ?  23  ARG   B CB  1 
ATOM   2443 C CG  . ARG   B 1 43  ? 12.30480  -12.84508 38.42871  1.000 42.10055 ?  23  ARG   B CG  1 
ATOM   2444 C CD  . ARG   B 1 43  ? 12.80078  -14.07821 39.16499  1.000 46.61241 ?  23  ARG   B CD  1 
ATOM   2445 N NE  . ARG   B 1 43  ? 12.61082  -13.96482 40.60585  1.000 51.61560 ?  23  ARG   B NE  1 
ATOM   2446 C CZ  . ARG   B 1 43  ? 13.49604  -13.43173 41.43648  1.000 54.53552 ?  23  ARG   B CZ  1 
ATOM   2447 N NH1 . ARG   B 1 43  ? 14.64878  -12.95027 41.00142  1.000 48.70837 ?  23  ARG   B NH1 1 
ATOM   2448 N NH2 . ARG   B 1 43  ? 13.21791  -13.38044 42.73607  1.000 57.97994 ?  23  ARG   B NH2 1 
ATOM   2449 N N   . ARG   B 1 44  ? 9.35712   -13.50947 35.25558  1.000 28.30004 ?  24  ARG   B N   1 
ATOM   2450 C CA  . ARG   B 1 44  ? 9.33567   -14.25613 34.00166  1.000 29.17707 ?  24  ARG   B CA  1 
ATOM   2451 C C   . ARG   B 1 44  ? 9.29502   -13.31470 32.80427  1.000 28.33703 ?  24  ARG   B C   1 
ATOM   2452 O O   . ARG   B 1 44  ? 10.00571  -13.52243 31.81345  1.000 28.83162 ?  24  ARG   B O   1 
ATOM   2453 C CB  . ARG   B 1 44  ? 8.14326   -15.21357 33.98083  1.000 26.51439 ?  24  ARG   B CB  1 
ATOM   2454 C CG  . ARG   B 1 44  ? 8.44743   -16.59286 34.54663  1.000 33.69210 ?  24  ARG   B CG  1 
ATOM   2455 C CD  . ARG   B 1 44  ? 7.26446   -17.53578 34.38872  1.000 37.39143 ?  24  ARG   B CD  1 
ATOM   2456 N NE  . ARG   B 1 44  ? 6.15791   -17.17990 35.26891  1.000 44.53563 ?  24  ARG   B NE  1 
ATOM   2457 C CZ  . ARG   B 1 44  ? 5.90142   -17.77157 36.42766  1.000 39.64860 ?  24  ARG   B CZ  1 
ATOM   2458 N NH1 . ARG   B 1 44  ? 6.65904   -18.75546 36.88423  1.000 33.32962 ?  24  ARG   B NH1 1 
ATOM   2459 N NH2 . ARG   B 1 44  ? 4.85924   -17.36486 37.14710  1.000 39.64350 ?  24  ARG   B NH2 1 
ATOM   2460 N N   . ILE   B 1 45  ? 8.46849   -12.26927 32.88002  1.000 27.17746 ?  25  ILE   B N   1 
ATOM   2461 C CA  . ILE   B 1 45  ? 8.38650   -11.30139 31.78867  1.000 22.88642 ?  25  ILE   B CA  1 
ATOM   2462 C C   . ILE   B 1 45  ? 9.72093   -10.58840 31.61112  1.000 26.01386 ?  25  ILE   B C   1 
ATOM   2463 O O   . ILE   B 1 45  ? 10.25134  -10.48941 30.49806  1.000 23.19630 ?  25  ILE   B O   1 
ATOM   2464 C CB  . ILE   B 1 45  ? 7.24507   -10.30045 32.04372  1.000 24.09796 ?  25  ILE   B CB  1 
ATOM   2465 C CG1 . ILE   B 1 45  ? 5.88839   -10.99625 31.93475  1.000 25.04036 ?  25  ILE   B CG1 1 
ATOM   2466 C CG2 . ILE   B 1 45  ? 7.32808   -9.13140  31.07416  1.000 24.25498 ?  25  ILE   B CG2 1 
ATOM   2467 C CD1 . ILE   B 1 45  ? 4.84405   -10.42653 32.85515  1.000 22.58388 ?  25  ILE   B CD1 1 
ATOM   2468 N N   . ARG   B 1 46  ? 10.29074  -10.09389 32.71197  1.000 29.00381 ?  26  ARG   B N   1 
ATOM   2469 C CA  . ARG   B 1 46  ? 11.50159  -9.28483  32.64691  1.000 26.76964 ?  26  ARG   B CA  1 
ATOM   2470 C C   . ARG   B 1 46  ? 12.74643  -10.09445 32.30733  1.000 27.67744 ?  26  ARG   B C   1 
ATOM   2471 O O   . ARG   B 1 46  ? 13.79945  -9.49862  32.05585  1.000 35.37281 ?  26  ARG   B O   1 
ATOM   2472 C CB  . ARG   B 1 46  ? 11.69377  -8.54107  33.96978  1.000 23.97934 ?  26  ARG   B CB  1 
ATOM   2473 C CG  . ARG   B 1 46  ? 12.28589  -9.35740  35.10154  1.000 30.82804 ?  26  ARG   B CG  1 
ATOM   2474 C CD  . ARG   B 1 46  ? 12.35351  -8.50406  36.35626  1.000 31.57442 ?  26  ARG   B CD  1 
ATOM   2475 N NE  . ARG   B 1 46  ? 12.82175  -9.23577  37.52629  1.000 30.85274 ?  26  ARG   B NE  1 
ATOM   2476 C CZ  . ARG   B 1 46  ? 14.09353  -9.32873  37.88923  1.000 33.83940 ?  26  ARG   B CZ  1 
ATOM   2477 N NH1 . ARG   B 1 46  ? 15.05740  -8.76339  37.18066  1.000 30.93247 ?  26  ARG   B NH1 1 
ATOM   2478 N NH2 . ARG   B 1 46  ? 14.40575  -10.00143 38.99329  1.000 30.49489 ?  26  ARG   B NH2 1 
ATOM   2479 N N   . THR   B 1 47  ? 12.65622  -11.42247 32.29012  1.000 27.88835 ?  27  THR   B N   1 
ATOM   2480 C CA  . THR   B 1 47  ? 13.74678  -12.27355 31.83713  1.000 29.66997 ?  27  THR   B CA  1 
ATOM   2481 C C   . THR   B 1 47  ? 13.42899  -12.98733 30.53197  1.000 29.43395 ?  27  THR   B C   1 
ATOM   2482 O O   . THR   B 1 47  ? 14.25839  -13.76592 30.04962  1.000 26.78541 ?  27  THR   B O   1 
ATOM   2483 C CB  . THR   B 1 47  ? 14.10240  -13.30856 32.91185  1.000 26.23064 ?  27  THR   B CB  1 
ATOM   2484 O OG1 . THR   B 1 47  ? 12.94747  -14.10059 33.21714  1.000 22.26282 ?  27  THR   B OG1 1 
ATOM   2485 C CG2 . THR   B 1 47  ? 14.59785  -12.62139 34.17602  1.000 22.02102 ?  27  THR   B CG2 1 
ATOM   2486 N N   . GLY   B 1 48  ? 12.26015  -12.74212 29.94880  1.000 27.18984 ?  28  GLY   B N   1 
ATOM   2487 C CA  . GLY   B 1 48  ? 11.86046  -13.43749 28.73835  1.000 29.16685 ?  28  GLY   B CA  1 
ATOM   2488 C C   . GLY   B 1 48  ? 11.65756  -14.92356 28.93581  1.000 30.97401 ?  28  GLY   B C   1 
ATOM   2489 O O   . GLY   B 1 48  ? 11.98526  -15.71450 28.04209  1.000 23.14115 ?  28  GLY   B O   1 
ATOM   2490 N N   . THR   B 1 49  ? 11.12471  -15.32622 30.08892  1.000 31.76186 ?  29  THR   B N   1 
ATOM   2491 C CA  . THR   B 1 49  ? 10.95025  -16.73493 30.41919  1.000 37.07815 ?  29  THR   B CA  1 
ATOM   2492 C C   . THR   B 1 49  ? 9.49197   -17.07242 30.70912  1.000 32.35411 ?  29  THR   B C   1 
ATOM   2493 O O   . THR   B 1 49  ? 9.20315   -18.01830 31.44447  1.000 34.72926 ?  29  THR   B O   1 
ATOM   2494 C CB  . THR   B 1 49  ? 11.83066  -17.12960 31.60394  1.000 24.49748 ?  29  THR   B CB  1 
ATOM   2495 O OG1 . THR   B 1 49  ? 11.71846  -16.14178 32.63584  1.000 25.35857 ?  29  THR   B OG1 1 
ATOM   2496 C CG2 . THR   B 1 49  ? 13.28326  -17.24659 31.16932  1.000 29.91414 ?  29  THR   B CG2 1 
ATOM   2497 N N   . VAL   B 1 50  ? 8.56356   -16.30336 30.14993  1.000 30.22848 ?  30  VAL   B N   1 
ATOM   2498 C CA  . VAL   B 1 50  ? 7.15202   -16.67093 30.20199  1.000 34.56073 ?  30  VAL   B CA  1 
ATOM   2499 C C   . VAL   B 1 50  ? 7.01625   -17.98275 29.43961  1.000 41.20901 ?  30  VAL   B C   1 
ATOM   2500 O O   . VAL   B 1 50  ? 7.31671   -18.03008 28.23772  1.000 40.91950 ?  30  VAL   B O   1 
ATOM   2501 C CB  . VAL   B 1 50  ? 6.25343   -15.56977 29.61683  1.000 31.17465 ?  30  VAL   B CB  1 
ATOM   2502 C CG1 . VAL   B 1 50  ? 4.78875   -15.98312 29.67814  1.000 30.87838 ?  30  VAL   B CG1 1 
ATOM   2503 C CG2 . VAL   B 1 50  ? 6.46790   -14.25988 30.35874  1.000 28.81083 ?  30  VAL   B CG2 1 
ATOM   2504 N N   . PRO   B 1 51  ? 6.58190   -19.06372 30.08365  1.000 38.74210 ?  31  PRO   B N   1 
ATOM   2505 C CA  . PRO   B 1 51  ? 6.63067   -20.37311 29.42368  1.000 40.82992 ?  31  PRO   B CA  1 
ATOM   2506 C C   . PRO   B 1 51  ? 5.62135   -20.45705 28.28989  1.000 36.97849 ?  31  PRO   B C   1 
ATOM   2507 O O   . PRO   B 1 51  ? 4.50909   -19.93207 28.37993  1.000 36.26028 ?  31  PRO   B O   1 
ATOM   2508 C CB  . PRO   B 1 51  ? 6.30015   -21.36407 30.54689  1.000 39.59213 ?  31  PRO   B CB  1 
ATOM   2509 C CG  . PRO   B 1 51  ? 5.82089   -20.54406 31.71753  1.000 40.04888 ?  31  PRO   B CG  1 
ATOM   2510 C CD  . PRO   B 1 51  ? 5.86088   -19.09306 31.36524  1.000 42.54890 ?  31  PRO   B CD  1 
ATOM   2511 N N   . ASP   B 1 52  ? 6.04019   -21.10101 27.20471  1.000 40.51366 ?  32  ASP   B N   1 
ATOM   2512 C CA  . ASP   B 1 52  ? 5.25429   -21.31267 25.99365  1.000 40.72627 ?  32  ASP   B CA  1 
ATOM   2513 C C   . ASP   B 1 52  ? 4.77947   -20.01436 25.35102  1.000 40.13386 ?  32  ASP   B C   1 
ATOM   2514 O O   . ASP   B 1 52  ? 3.90309   -20.04834 24.47841  1.000 42.47605 ?  32  ASP   B O   1 
ATOM   2515 C CB  . ASP   B 1 52  ? 4.05485   -22.23029 26.26123  1.000 33.99450 ?  32  ASP   B CB  1 
ATOM   2516 C CG  . ASP   B 1 52  ? 4.42785   -23.45668 27.06804  1.000 40.26482 ?  32  ASP   B CG  1 
ATOM   2517 O OD1 . ASP   B 1 52  ? 5.60767   -23.86932 27.03520  1.000 41.42587 ?  32  ASP   B OD1 1 
ATOM   2518 O OD2 . ASP   B 1 52  ? 3.53051   -24.01067 27.73681  1.000 40.34746 ?  32  ASP   B OD2 1 
ATOM   2519 N N   . LEU   B 1 53  ? 5.33954   -18.87467 25.74257  1.000 43.53440 ?  33  LEU   B N   1 
ATOM   2520 C CA  . LEU   B 1 53  ? 4.92047   -17.58242 25.20949  1.000 44.85983 ?  33  LEU   B CA  1 
ATOM   2521 C C   . LEU   B 1 53  ? 5.32394   -17.40710 23.74901  1.000 52.70969 ?  33  LEU   B C   1 
ATOM   2522 O O   . LEU   B 1 53  ? 4.54632   -17.68780 22.83747  1.000 57.31318 ?  33  LEU   B O   1 
ATOM   2523 C CB  . LEU   B 1 53  ? 5.50621   -16.44588 26.04866  1.000 43.49804 ?  33  LEU   B CB  1 
ATOM   2524 N N   . GLY   B 1 55  ? 4.67128   -15.21428 17.79500  1.000 42.85140 ?  35  GLY   B N   1 
ATOM   2525 C CA  . GLY   B 1 55  ? 6.10672   -15.20584 18.00694  1.000 50.55437 ?  35  GLY   B CA  1 
ATOM   2526 C C   . GLY   B 1 55  ? 6.66617   -13.80353 18.13364  1.000 47.22779 ?  35  GLY   B C   1 
ATOM   2527 O O   . GLY   B 1 55  ? 6.21161   -12.88541 17.45384  1.000 54.43138 ?  35  GLY   B O   1 
ATOM   2528 N N   . SER   B 1 56  ? 7.66146   -13.63795 19.00462  1.000 46.06050 ?  36  SER   B N   1 
ATOM   2529 C CA  . SER   B 1 56  ? 8.25571   -12.33720 19.27688  1.000 42.87525 ?  36  SER   B CA  1 
ATOM   2530 C C   . SER   B 1 56  ? 9.57681   -12.12832 18.54032  1.000 43.33362 ?  36  SER   B C   1 
ATOM   2531 O O   . SER   B 1 56  ? 10.37077  -11.26529 18.93294  1.000 32.01172 ?  36  SER   B O   1 
ATOM   2532 C CB  . SER   B 1 56  ? 8.43745   -12.15080 20.78249  1.000 39.18768 ?  36  SER   B CB  1 
ATOM   2533 O OG  . SER   B 1 56  ? 7.33717   -12.68504 21.49652  1.000 47.64775 ?  36  SER   B OG  1 
ATOM   2534 N N   . TYR   B 1 57  ? 9.82104   -12.90257 17.48094  1.000 39.38920 ?  37  TYR   B N   1 
ATOM   2535 C CA  . TYR   B 1 57  ? 10.85850  -12.60195 16.49188  1.000 36.92897 ?  37  TYR   B CA  1 
ATOM   2536 C C   . TYR   B 1 57  ? 12.24969  -12.51159 17.11666  1.000 40.08647 ?  37  TYR   B C   1 
ATOM   2537 O O   . TYR   B 1 57  ? 13.03232  -11.61068 16.80521  1.000 36.85678 ?  37  TYR   B O   1 
ATOM   2538 C CB  . TYR   B 1 57  ? 10.52834  -11.31721 15.73157  1.000 39.12339 ?  37  TYR   B CB  1 
ATOM   2539 C CG  . TYR   B 1 57  ? 9.04909   -11.01178 15.62262  1.000 40.70416 ?  37  TYR   B CG  1 
ATOM   2540 C CD1 . TYR   B 1 57  ? 8.24070   -11.70112 14.72742  1.000 37.07712 ?  37  TYR   B CD1 1 
ATOM   2541 C CD2 . TYR   B 1 57  ? 8.46406   -10.02596 16.40838  1.000 39.28694 ?  37  TYR   B CD2 1 
ATOM   2542 C CE1 . TYR   B 1 57  ? 6.89130   -11.41944 14.62257  1.000 34.39729 ?  37  TYR   B CE1 1 
ATOM   2543 C CE2 . TYR   B 1 57  ? 7.11950   -9.73945  16.31105  1.000 37.03741 ?  37  TYR   B CE2 1 
ATOM   2544 C CZ  . TYR   B 1 57  ? 6.33747   -10.43696 15.41816  1.000 31.83758 ?  37  TYR   B CZ  1 
ATOM   2545 O OH  . TYR   B 1 57  ? 4.99648   -10.14550 15.32606  1.000 30.65439 ?  37  TYR   B OH  1 
ATOM   2546 N N   . GLY   B 1 58  ? 12.56310  -13.45335 18.00245  1.000 35.80128 ?  38  GLY   B N   1 
ATOM   2547 C CA  . GLY   B 1 58  ? 13.89266  -13.51483 18.57588  1.000 37.24479 ?  38  GLY   B CA  1 
ATOM   2548 C C   . GLY   B 1 58  ? 14.22592  -12.41537 19.55538  1.000 42.10495 ?  38  GLY   B C   1 
ATOM   2549 O O   . GLY   B 1 58  ? 15.40601  -12.14896 19.79183  1.000 48.16986 ?  38  GLY   B O   1 
ATOM   2550 N N   . GLN   B 1 59  ? 13.21943  -11.75945 20.12617  1.000 38.87342 ?  39  GLN   B N   1 
ATOM   2551 C CA  . GLN   B 1 59  ? 13.43810  -10.75001 21.15035  1.000 36.83375 ?  39  GLN   B CA  1 
ATOM   2552 C C   . GLN   B 1 59  ? 12.24253  -10.75973 22.08922  1.000 32.07668 ?  39  GLN   B C   1 
ATOM   2553 O O   . GLN   B 1 59  ? 11.17097  -11.26171 21.74689  1.000 34.69081 ?  39  GLN   B O   1 
ATOM   2554 C CB  . GLN   B 1 59  ? 13.65343  -9.35650  20.54018  1.000 38.09225 ?  39  GLN   B CB  1 
ATOM   2555 C CG  . GLN   B 1 59  ? 12.54737  -8.88610  19.60220  1.000 33.84528 ?  39  GLN   B CG  1 
ATOM   2556 C CD  . GLN   B 1 59  ? 11.36200  -8.28857  20.33806  1.000 30.34930 ?  39  GLN   B CD  1 
ATOM   2557 O OE1 . GLN   B 1 59  ? 11.51257  -7.35509  21.12642  1.000 27.22672 ?  39  GLN   B OE1 1 
ATOM   2558 N NE2 . GLN   B 1 59  ? 10.17542  -8.82755  20.08506  1.000 25.01050 ?  39  GLN   B NE2 1 
ATOM   2559 N N   . TYR   B 1 60  ? 12.43311  -10.20332 23.28827  1.000 29.44950 ?  40  TYR   B N   1 
ATOM   2560 C CA  . TYR   B 1 60  ? 11.35077  -10.14902 24.26476  1.000 29.89745 ?  40  TYR   B CA  1 
ATOM   2561 C C   . TYR   B 1 60  ? 11.16491  -8.75162  24.84733  1.000 28.52355 ?  40  TYR   B C   1 
ATOM   2562 O O   . TYR   B 1 60  ? 10.59420  -8.61343  25.93403  1.000 27.74024 ?  40  TYR   B O   1 
ATOM   2563 C CB  . TYR   B 1 60  ? 11.57092  -11.16733 25.38881  1.000 32.85171 ?  40  TYR   B CB  1 
ATOM   2564 C CG  . TYR   B 1 60  ? 12.85416  -10.98851 26.16808  1.000 30.39944 ?  40  TYR   B CG  1 
ATOM   2565 C CD1 . TYR   B 1 60  ? 14.03479  -11.58574 25.74701  1.000 34.49045 ?  40  TYR   B CD1 1 
ATOM   2566 C CD2 . TYR   B 1 60  ? 12.88220  -10.23129 27.33217  1.000 32.99003 ?  40  TYR   B CD2 1 
ATOM   2567 C CE1 . TYR   B 1 60  ? 15.20825  -11.42810 26.45951  1.000 33.61690 ?  40  TYR   B CE1 1 
ATOM   2568 C CE2 . TYR   B 1 60  ? 14.05066  -10.06674 28.05044  1.000 34.74069 ?  40  TYR   B CE2 1 
ATOM   2569 C CZ  . TYR   B 1 60  ? 15.21070  -10.66780 27.60941  1.000 36.26825 ?  40  TYR   B CZ  1 
ATOM   2570 O OH  . TYR   B 1 60  ? 16.37812  -10.50862 28.32027  1.000 42.03349 ?  40  TYR   B OH  1 
ATOM   2571 N N   . PHE   B 1 61  ? 11.62338  -7.71087  24.14779  1.000 28.71621 ?  41  PHE   B N   1 
ATOM   2572 C CA  . PHE   B 1 61  ? 11.40098  -6.34927  24.62390  1.000 28.84257 ?  41  PHE   B CA  1 
ATOM   2573 C C   . PHE   B 1 61  ? 9.97174   -5.89366  24.35872  1.000 22.12230 ?  41  PHE   B C   1 
ATOM   2574 O O   . PHE   B 1 61  ? 9.34228   -5.27235  25.22179  1.000 22.97431 ?  41  PHE   B O   1 
ATOM   2575 C CB  . PHE   B 1 61  ? 12.38559  -5.37845  23.96806  1.000 24.16761 ?  41  PHE   B CB  1 
ATOM   2576 C CG  . PHE   B 1 61  ? 11.97726  -3.93536  24.09298  1.000 28.21050 ?  41  PHE   B CG  1 
ATOM   2577 C CD1 . PHE   B 1 61  ? 11.87655  -3.33426  25.33761  1.000 25.88791 ?  41  PHE   B CD1 1 
ATOM   2578 C CD2 . PHE   B 1 61  ? 11.67211  -3.18668  22.96682  1.000 25.55888 ?  41  PHE   B CD2 1 
ATOM   2579 C CE1 . PHE   B 1 61  ? 11.49191  -2.01099  25.45774  1.000 25.64005 ?  41  PHE   B CE1 1 
ATOM   2580 C CE2 . PHE   B 1 61  ? 11.28774  -1.86129  23.08042  1.000 28.07839 ?  41  PHE   B CE2 1 
ATOM   2581 C CZ  . PHE   B 1 61  ? 11.19830  -1.27344  24.32746  1.000 29.56961 ?  41  PHE   B CZ  1 
ATOM   2582 N N   . THR   B 1 62  ? 9.44846   -6.18500  23.16521  1.000 21.49384 ?  42  THR   B N   1 
ATOM   2583 C CA  . THR   B 1 62  ? 8.11768   -5.70530  22.80442  1.000 26.15110 ?  42  THR   B CA  1 
ATOM   2584 C C   . THR   B 1 62  ? 7.05417   -6.28377  23.73028  1.000 22.00546 ?  42  THR   B C   1 
ATOM   2585 O O   . THR   B 1 62  ? 6.19159   -5.55469  24.23320  1.000 24.23965 ?  42  THR   B O   1 
ATOM   2586 C CB  . THR   B 1 62  ? 7.80960   -6.04385  21.34511  1.000 24.77704 ?  42  THR   B CB  1 
ATOM   2587 O OG1 . THR   B 1 62  ? 7.78038   -7.46678  21.17319  1.000 19.75983 ?  42  THR   B OG1 1 
ATOM   2588 C CG2 . THR   B 1 62  ? 8.86149   -5.43996  20.42321  1.000 21.20415 ?  42  THR   B CG2 1 
ATOM   2589 N N   . ALA   B 1 63  ? 7.10284   -7.59642  23.97262  1.000 22.26009 ?  43  ALA   B N   1 
ATOM   2590 C CA  . ALA   B 1 63  ? 6.17164   -8.20241  24.91942  1.000 26.84385 ?  43  ALA   B CA  1 
ATOM   2591 C C   . ALA   B 1 63  ? 6.35474   -7.61850  26.31421  1.000 24.23762 ?  43  ALA   B C   1 
ATOM   2592 O O   . ALA   B 1 63  ? 5.37694   -7.40180  27.03950  1.000 24.40534 ?  43  ALA   B O   1 
ATOM   2593 C CB  . ALA   B 1 63  ? 6.35334   -9.71980  24.94049  1.000 30.06312 ?  43  ALA   B CB  1 
ATOM   2594 N N   . TRP   B 1 64  ? 7.60492   -7.35817  26.70398  1.000 23.78229 ?  44  TRP   B N   1 
ATOM   2595 C CA  . TRP   B 1 64  ? 7.87237   -6.65425  27.95392  1.000 22.60702 ?  44  TRP   B CA  1 
ATOM   2596 C C   . TRP   B 1 64  ? 7.23728   -5.26944  27.95019  1.000 20.69210 ?  44  TRP   B C   1 
ATOM   2597 O O   . TRP   B 1 64  ? 6.66465   -4.83574  28.95716  1.000 19.19452 ?  44  TRP   B O   1 
ATOM   2598 C CB  . TRP   B 1 64  ? 9.38252   -6.55206  28.16614  1.000 26.10929 ?  44  TRP   B CB  1 
ATOM   2599 C CG  . TRP   B 1 64  ? 9.81555   -6.24510  29.56429  1.000 23.86084 ?  44  TRP   B CG  1 
ATOM   2600 C CD1 . TRP   B 1 64  ? 9.01973   -5.94545  30.63186  1.000 24.59425 ?  44  TRP   B CD1 1 
ATOM   2601 C CD2 . TRP   B 1 64  ? 11.16299  -6.20234  30.04274  1.000 21.76029 ?  44  TRP   B CD2 1 
ATOM   2602 N NE1 . TRP   B 1 64  ? 9.79180   -5.72210  31.74762  1.000 21.57352 ?  44  TRP   B NE1 1 
ATOM   2603 C CE2 . TRP   B 1 64  ? 11.11158  -5.87363  31.41073  1.000 24.78571 ?  44  TRP   B CE2 1 
ATOM   2604 C CE3 . TRP   B 1 64  ? 12.40952  -6.41232  29.44528  1.000 23.50373 ?  44  TRP   B CE3 1 
ATOM   2605 C CZ2 . TRP   B 1 64  ? 12.25922  -5.74800  32.19060  1.000 25.56926 ?  44  TRP   B CZ2 1 
ATOM   2606 C CZ3 . TRP   B 1 64  ? 13.54630  -6.28954  30.22083  1.000 29.00890 ?  44  TRP   B CZ3 1 
ATOM   2607 C CH2 . TRP   B 1 64  ? 13.46382  -5.96200  31.57912  1.000 27.85553 ?  44  TRP   B CH2 1 
ATOM   2608 N N   . ASP   B 1 65  ? 7.32769   -4.56279  26.82122  1.000 19.53713 ?  45  ASP   B N   1 
ATOM   2609 C CA  . ASP   B 1 65  ? 6.76539   -3.21924  26.72941  1.000 21.12383 ?  45  ASP   B CA  1 
ATOM   2610 C C   . ASP   B 1 65  ? 5.25028   -3.24441  26.88200  1.000 22.13143 ?  45  ASP   B C   1 
ATOM   2611 O O   . ASP   B 1 65  ? 4.67285   -2.43118  27.61296  1.000 18.39857 ?  45  ASP   B O   1 
ATOM   2612 C CB  . ASP   B 1 65  ? 7.15984   -2.58231  25.39724  1.000 21.65320 ?  45  ASP   B CB  1 
ATOM   2613 C CG  . ASP   B 1 65  ? 7.02148   -1.07763  25.41062  1.000 25.76638 ?  45  ASP   B CG  1 
ATOM   2614 O OD1 . ASP   B 1 65  ? 7.83030   -0.41998  26.09394  1.000 26.37524 ?  45  ASP   B OD1 1 
ATOM   2615 O OD2 . ASP   B 1 65  ? 6.10727   -0.55415  24.74003  1.000 24.69796 ?  45  ASP   B OD2 1 
ATOM   2616 N N   . PHE   B 1 66  ? 4.58715   -4.17276  26.19068  1.000 20.64477 ?  46  PHE   B N   1 
ATOM   2617 C CA  . PHE   B 1 66  ? 3.13409   -4.25598  26.27867  1.000 23.22246 ?  46  PHE   B CA  1 
ATOM   2618 C C   . PHE   B 1 66  ? 2.68992   -4.73190  27.65578  1.000 23.15920 ?  46  PHE   B C   1 
ATOM   2619 O O   . PHE   B 1 66  ? 1.73950   -4.18631  28.22562  1.000 22.18901 ?  46  PHE   B O   1 
ATOM   2620 C CB  . PHE   B 1 66  ? 2.59515   -5.17836  25.18589  1.000 19.95714 ?  46  PHE   B CB  1 
ATOM   2621 C CG  . PHE   B 1 66  ? 2.48668   -4.52204  23.83829  1.000 20.00324 ?  46  PHE   B CG  1 
ATOM   2622 C CD1 . PHE   B 1 66  ? 3.62050   -4.26405  23.08664  1.000 21.39390 ?  46  PHE   B CD1 1 
ATOM   2623 C CD2 . PHE   B 1 66  ? 1.25127   -4.16714  23.32073  1.000 21.69462 ?  46  PHE   B CD2 1 
ATOM   2624 C CE1 . PHE   B 1 66  ? 3.52535   -3.66465  21.84682  1.000 19.61631 ?  46  PHE   B CE1 1 
ATOM   2625 C CE2 . PHE   B 1 66  ? 1.15025   -3.56528  22.08033  1.000 20.80046 ?  46  PHE   B CE2 1 
ATOM   2626 C CZ  . PHE   B 1 66  ? 2.28901   -3.31362  21.34302  1.000 21.27108 ?  46  PHE   B CZ  1 
ATOM   2627 N N   . SER   B 1 67  ? 3.37235   -5.73690  28.21126  1.000 18.75864 ?  47  SER   B N   1 
ATOM   2628 C CA  . SER   B 1 67  ? 2.99005   -6.26585  29.51793  1.000 21.04501 ?  47  SER   B CA  1 
ATOM   2629 C C   . SER   B 1 67  ? 3.04242   -5.18308  30.58829  1.000 22.10984 ?  47  SER   B C   1 
ATOM   2630 O O   . SER   B 1 67  ? 2.11632   -5.04696  31.39549  1.000 19.83874 ?  47  SER   B O   1 
ATOM   2631 C CB  . SER   B 1 67  ? 3.89835   -7.43639  29.89559  1.000 19.56613 ?  47  SER   B CB  1 
ATOM   2632 O OG  . SER   B 1 67  ? 3.96067   -8.39093  28.85040  1.000 33.68213 ?  47  SER   B OG  1 
ATOM   2633 N N   . ASN   B 1 68  ? 4.12008   -4.39635  30.60288  1.000 22.04304 ?  48  ASN   B N   1 
ATOM   2634 C CA  . ASN   B 1 68  ? 4.27615   -3.36167  31.62023  1.000 20.53470 ?  48  ASN   B CA  1 
ATOM   2635 C C   . ASN   B 1 68  ? 3.20471   -2.28611  31.48967  1.000 18.58684 ?  48  ASN   B C   1 
ATOM   2636 O O   . ASN   B 1 68  ? 2.56828   -1.90180  32.47760  1.000 20.72727 ?  48  ASN   B O   1 
ATOM   2637 C CB  . ASN   B 1 68  ? 5.66849   -2.74211  31.51986  1.000 18.41077 ?  48  ASN   B CB  1 
ATOM   2638 C CG  . ASN   B 1 68  ? 5.88299   -1.63028  32.52580  1.000 23.92565 ?  48  ASN   B CG  1 
ATOM   2639 O OD1 . ASN   B 1 68  ? 5.94612   -1.87023  33.73086  1.000 22.67491 ?  48  ASN   B OD1 1 
ATOM   2640 N ND2 . ASN   B 1 68  ? 5.98944   -0.40073  32.03361  1.000 22.67508 ?  48  ASN   B ND2 1 
ATOM   2641 N N   . SER   B 1 69  ? 2.99343   -1.78349  30.27311  1.000 17.34558 ?  49  SER   B N   1 
ATOM   2642 C CA  . SER   B 1 69  ? 2.08328   -0.65823  30.09525  1.000 18.96927 ?  49  SER   B CA  1 
ATOM   2643 C C   . SER   B 1 69  ? 0.62865   -1.09349  30.20729  1.000 18.46022 ?  49  SER   B C   1 
ATOM   2644 O O   . SER   B 1 69  ? -0.20520  -0.35438  30.74355  1.000 16.43013 ?  49  SER   B O   1 
ATOM   2645 C CB  . SER   B 1 69  ? 2.34111   0.01291   28.74897  1.000 18.36729 ?  49  SER   B CB  1 
ATOM   2646 O OG  . SER   B 1 69  ? 2.25647   -0.91812  27.68366  1.000 17.77412 ?  49  SER   B OG  1 
ATOM   2647 N N   . ILE   B 1 70  ? 0.30415   -2.28933  29.71321  1.000 17.12855 ?  50  ILE   B N   1 
ATOM   2648 C CA  . ILE   B 1 70  ? -1.08471  -2.73508  29.73105  1.000 21.95294 ?  50  ILE   B CA  1 
ATOM   2649 C C   . ILE   B 1 70  ? -1.52282  -3.07462  31.15058  1.000 18.15693 ?  50  ILE   B C   1 
ATOM   2650 O O   . ILE   B 1 70  ? -2.65181  -2.76822  31.54964  1.000 15.43242 ?  50  ILE   B O   1 
ATOM   2651 C CB  . ILE   B 1 70  ? -1.28125  -3.91643  28.76315  1.000 21.08426 ?  50  ILE   B CB  1 
ATOM   2652 C CG1 . ILE   B 1 70  ? -1.26240  -3.40894  27.31909  1.000 22.78434 ?  50  ILE   B CG1 1 
ATOM   2653 C CG2 . ILE   B 1 70  ? -2.58457  -4.64505  29.04809  1.000 22.65641 ?  50  ILE   B CG2 1 
ATOM   2654 C CD1 . ILE   B 1 70  ? -1.44156  -4.48857  26.28460  1.000 25.53912 ?  50  ILE   B CD1 1 
ATOM   2655 N N   . VAL   B 1 71  ? -0.64048  -3.68845  31.94516  1.000 19.31865 ?  51  VAL   B N   1 
ATOM   2656 C CA  . VAL   B 1 71  ? -1.01323  -3.98333  33.32601  1.000 16.20949 ?  51  VAL   B CA  1 
ATOM   2657 C C   . VAL   B 1 71  ? -1.14877  -2.69484  34.12964  1.000 19.27341 ?  51  VAL   B C   1 
ATOM   2658 O O   . VAL   B 1 71  ? -1.97346  -2.61351  35.04883  1.000 20.23659 ?  51  VAL   B O   1 
ATOM   2659 C CB  . VAL   B 1 71  ? -0.01013  -4.96005  33.97587  1.000 21.80961 ?  51  VAL   B CB  1 
ATOM   2660 C CG1 . VAL   B 1 71  ? 1.29874   -4.26291  34.33204  1.000 15.81086 ?  51  VAL   B CG1 1 
ATOM   2661 C CG2 . VAL   B 1 71  ? -0.62579  -5.59992  35.20912  1.000 23.55872 ?  51  VAL   B CG2 1 
ATOM   2662 N N   . ARG   B 1 72  ? -0.36383  -1.66692  33.79578  1.000 18.84718 ?  52  ARG   B N   1 
ATOM   2663 C CA  . ARG   B 1 72  ? -0.49574  -0.38600  34.48044  1.000 17.10943 ?  52  ARG   B CA  1 
ATOM   2664 C C   . ARG   B 1 72  ? -1.81065  0.28803   34.11685  1.000 14.53778 ?  52  ARG   B C   1 
ATOM   2665 O O   . ARG   B 1 72  ? -2.53476  0.77762   34.99112  1.000 16.61026 ?  52  ARG   B O   1 
ATOM   2666 C CB  . ARG   B 1 72  ? 0.68498   0.52165   34.13312  1.000 15.54250 ?  52  ARG   B CB  1 
ATOM   2667 C CG  . ARG   B 1 72  ? 0.48306   1.97658   34.53672  1.000 18.46618 ?  52  ARG   B CG  1 
ATOM   2668 C CD  . ARG   B 1 72  ? 1.38890   2.90066   33.73567  1.000 23.62401 ?  52  ARG   B CD  1 
ATOM   2669 N NE  . ARG   B 1 72  ? 0.97819   2.98790   32.33896  1.000 18.15724 ?  52  ARG   B NE  1 
ATOM   2670 C CZ  . ARG   B 1 72  ? 1.80817   2.92513   31.30629  1.000 19.20253 ?  52  ARG   B CZ  1 
ATOM   2671 N NH1 . ARG   B 1 72  ? 3.11208   2.77677   31.47468  1.000 18.52630 ?  52  ARG   B NH1 1 
ATOM   2672 N NH2 . ARG   B 1 72  ? 1.31751   3.01444   30.07314  1.000 18.46060 ?  52  ARG   B NH2 1 
ATOM   2673 N N   . ASP   B 1 73  ? -2.13640  0.31668   32.82377  1.000 16.68700 ?  53  ASP   B N   1 
ATOM   2674 C CA  . ASP   B 1 73  ? -3.36161  0.96814   32.38182  1.000 15.07967 ?  53  ASP   B CA  1 
ATOM   2675 C C   . ASP   B 1 73  ? -4.59124  0.12876   32.70780  1.000 20.59241 ?  53  ASP   B C   1 
ATOM   2676 O O   . ASP   B 1 73  ? -5.68100  0.68026   32.90075  1.000 19.23522 ?  53  ASP   B O   1 
ATOM   2677 C CB  . ASP   B 1 73  ? -3.26838  1.26726   30.88634  1.000 19.37640 ?  53  ASP   B CB  1 
ATOM   2678 C CG  . ASP   B 1 73  ? -2.14489  2.23767   30.56165  1.000 21.37916 ?  53  ASP   B CG  1 
ATOM   2679 O OD1 . ASP   B 1 73  ? -1.62240  2.87087   31.50282  1.000 20.68513 ?  53  ASP   B OD1 1 
ATOM   2680 O OD2 . ASP   B 1 73  ? -1.78101  2.37154   29.37548  1.000 19.72028 ?  53  ASP   B OD2 1 
ATOM   2681 N N   . TYR   B 1 74  ? -4.43804  -1.19661  32.77644  1.000 21.20138 ?  54  TYR   B N   1 
ATOM   2682 C CA  . TYR   B 1 74  ? -5.50333  -2.04282  33.30656  1.000 18.78569 ?  54  TYR   B CA  1 
ATOM   2683 C C   . TYR   B 1 74  ? -5.81422  -1.67619  34.75033  1.000 17.52313 ?  54  TYR   B C   1 
ATOM   2684 O O   . TYR   B 1 74  ? -6.98229  -1.56755  35.14149  1.000 15.07443 ?  54  TYR   B O   1 
ATOM   2685 C CB  . TYR   B 1 74  ? -5.10203  -3.51448  33.20265  1.000 15.89138 ?  54  TYR   B CB  1 
ATOM   2686 C CG  . TYR   B 1 74  ? -6.17505  -4.49364  33.61972  1.000 20.01331 ?  54  TYR   B CG  1 
ATOM   2687 C CD1 . TYR   B 1 74  ? -7.46398  -4.39586  33.11764  1.000 15.19254 ?  54  TYR   B CD1 1 
ATOM   2688 C CD2 . TYR   B 1 74  ? -5.89217  -5.52909  34.50208  1.000 20.63815 ?  54  TYR   B CD2 1 
ATOM   2689 C CE1 . TYR   B 1 74  ? -8.44449  -5.29462  33.48495  1.000 17.98828 ?  54  TYR   B CE1 1 
ATOM   2690 C CE2 . TYR   B 1 74  ? -6.86753  -6.43301  34.87763  1.000 16.33606 ?  54  TYR   B CE2 1 
ATOM   2691 C CZ  . TYR   B 1 74  ? -8.14112  -6.31075  34.36502  1.000 15.37539 ?  54  TYR   B CZ  1 
ATOM   2692 O OH  . TYR   B 1 74  ? -9.11804  -7.20458  34.73269  1.000 16.91346 ?  54  TYR   B OH  1 
ATOM   2693 N N   . ALA   B 1 75  ? -4.76984  -1.48617  35.55967  1.000 21.61561 ?  55  ALA   B N   1 
ATOM   2694 C CA  . ALA   B 1 75  ? -4.96441  -1.08035  36.94652  1.000 20.35155 ?  55  ALA   B CA  1 
ATOM   2695 C C   . ALA   B 1 75  ? -5.63655  0.28337   37.03040  1.000 20.47310 ?  55  ALA   B C   1 
ATOM   2696 O O   . ALA   B 1 75  ? -6.46014  0.52573   37.92105  1.000 16.77140 ?  55  ALA   B O   1 
ATOM   2697 C CB  . ALA   B 1 75  ? -3.62141  -1.06599  37.67593  1.000 21.09890 ?  55  ALA   B CB  1 
ATOM   2698 N N   . MET   B 1 76  ? -5.30088  1.18527   36.10447  1.000 20.87982 ?  56  MET   B N   1 
ATOM   2699 C CA  . MET   B 1 76  ? -5.92333  2.50405   36.09399  1.000 19.18245 ?  56  MET   B CA  1 
ATOM   2700 C C   . MET   B 1 76  ? -7.41408  2.40167   35.79880  1.000 18.66081 ?  56  MET   B C   1 
ATOM   2701 O O   . MET   B 1 76  ? -8.22446  3.10967   36.40741  1.000 17.38342 ?  56  MET   B O   1 
ATOM   2702 C CB  . MET   B 1 76  ? -5.22605  3.40042   35.07104  1.000 21.87405 ?  56  MET   B CB  1 
ATOM   2703 C CG  . MET   B 1 76  ? -4.02280  4.14298   35.63248  1.000 23.91108 ?  56  MET   B CG  1 
ATOM   2704 S SD  . MET   B 1 76  ? -3.58723  5.63047   34.71313  1.000 25.09509 ?  56  MET   B SD  1 
ATOM   2705 C CE  . MET   B 1 76  ? -3.68156  5.03643   33.02494  1.000 21.66868 ?  56  MET   B CE  1 
ATOM   2706 N N   . ASN   B 1 77  ? -7.79547  1.51980   34.87025  1.000 18.16367 ?  57  ASN   B N   1 
ATOM   2707 C CA  . ASN   B 1 77  ? -9.21241  1.29048   34.60508  1.000 18.87140 ?  57  ASN   B CA  1 
ATOM   2708 C C   . ASN   B 1 77  ? -9.90810  0.68295   35.81520  1.000 18.40468 ?  57  ASN   B C   1 
ATOM   2709 O O   . ASN   B 1 77  ? -11.04810 1.04281   36.13166  1.000 16.91373 ?  57  ASN   B O   1 
ATOM   2710 C CB  . ASN   B 1 77  ? -9.38390  0.37798   33.39080  1.000 17.37941 ?  57  ASN   B CB  1 
ATOM   2711 C CG  . ASN   B 1 77  ? -8.88916  1.00923   32.11051  1.000 20.91149 ?  57  ASN   B CG  1 
ATOM   2712 O OD1 . ASN   B 1 77  ? -8.59866  2.20283   32.06365  1.000 22.88509 ?  57  ASN   B OD1 1 
ATOM   2713 N ND2 . ASN   B 1 77  ? -8.79301  0.20658   31.05722  1.000 21.07192 ?  57  ASN   B ND2 1 
ATOM   2714 N N   . LEU   B 1 78  ? -9.23599  -0.24249  36.50418  1.000 16.54252 ?  58  LEU   B N   1 
ATOM   2715 C CA  . LEU   B 1 78  ? -9.87278  -0.94974  37.61020  1.000 17.68831 ?  58  LEU   B CA  1 
ATOM   2716 C C   . LEU   B 1 78  ? -10.19447 -0.01114  38.76500  1.000 18.93870 ?  58  LEU   B C   1 
ATOM   2717 O O   . LEU   B 1 78  ? -11.22838 -0.16518  39.42580  1.000 16.63850 ?  58  LEU   B O   1 
ATOM   2718 C CB  . LEU   B 1 78  ? -8.98183  -2.09631  38.08361  1.000 17.52592 ?  58  LEU   B CB  1 
ATOM   2719 C CG  . LEU   B 1 78  ? -8.92078  -3.31102  37.15796  1.000 20.05470 ?  58  LEU   B CG  1 
ATOM   2720 C CD1 . LEU   B 1 78  ? -7.83480  -4.26377  37.61498  1.000 15.67528 ?  58  LEU   B CD1 1 
ATOM   2721 C CD2 . LEU   B 1 78  ? -10.26948 -4.01282  37.10624  1.000 15.84086 ?  58  LEU   B CD2 1 
ATOM   2722 N N   . TYR   B 1 79  ? -9.32210  0.96422   39.03240  1.000 17.01772 ?  59  TYR   B N   1 
ATOM   2723 C CA  . TYR   B 1 79  ? -9.61225  1.90470   40.10950  1.000 17.02707 ?  59  TYR   B CA  1 
ATOM   2724 C C   . TYR   B 1 79  ? -10.79467 2.79672   39.75955  1.000 22.16227 ?  59  TYR   B C   1 
ATOM   2725 O O   . TYR   B 1 79  ? -11.64593 3.06950   40.61327  1.000 21.25672 ?  59  TYR   B O   1 
ATOM   2726 C CB  . TYR   B 1 79  ? -8.39323  2.76349   40.43847  1.000 18.38466 ?  59  TYR   B CB  1 
ATOM   2727 C CG  . TYR   B 1 79  ? -8.71439  3.78618   41.50356  1.000 23.47697 ?  59  TYR   B CG  1 
ATOM   2728 C CD1 . TYR   B 1 79  ? -8.79243  3.41678   42.83868  1.000 26.14869 ?  59  TYR   B CD1 1 
ATOM   2729 C CD2 . TYR   B 1 79  ? -8.98119  5.10995   41.17244  1.000 25.22599 ?  59  TYR   B CD2 1 
ATOM   2730 C CE1 . TYR   B 1 79  ? -9.10418  4.33748   43.81744  1.000 29.34181 ?  59  TYR   B CE1 1 
ATOM   2731 C CE2 . TYR   B 1 79  ? -9.29610  6.03931   42.14649  1.000 24.36652 ?  59  TYR   B CE2 1 
ATOM   2732 C CZ  . TYR   B 1 79  ? -9.35647  5.64635   43.46690  1.000 26.57312 ?  59  TYR   B CZ  1 
ATOM   2733 O OH  . TYR   B 1 79  ? -9.66884  6.56461   44.44256  1.000 22.78224 ?  59  TYR   B OH  1 
ATOM   2734 N N   . GLN   B 1 80  ? -10.85755 3.27449   38.51561  1.000 20.17743 ?  60  GLN   B N   1 
ATOM   2735 C CA  . GLN   B 1 80  ? -12.00251 4.07658   38.10106  1.000 20.87119 ?  60  GLN   B CA  1 
ATOM   2736 C C   . GLN   B 1 80  ? -13.28689 3.26111   38.14851  1.000 20.81652 ?  60  GLN   B C   1 
ATOM   2737 O O   . GLN   B 1 80  ? -14.35677 3.79256   38.46678  1.000 23.85139 ?  60  GLN   B O   1 
ATOM   2738 C CB  . GLN   B 1 80  ? -11.77034 4.64422   36.70411  1.000 19.82772 ?  60  GLN   B CB  1 
ATOM   2739 C CG  . GLN   B 1 80  ? -10.64374 5.66564   36.63368  1.000 20.20084 ?  60  GLN   B CG  1 
ATOM   2740 C CD  . GLN   B 1 80  ? -10.69532 6.68511   37.76172  1.000 24.29269 ?  60  GLN   B CD  1 
ATOM   2741 O OE1 . GLN   B 1 80  ? -11.75495 7.22391   38.08839  1.000 24.02866 ?  60  GLN   B OE1 1 
ATOM   2742 N NE2 . GLN   B 1 80  ? -9.54254  6.95349   38.36321  1.000 22.94257 ?  60  GLN   B NE2 1 
ATOM   2743 N N   . LEU   B 1 81  ? -13.20042 1.96585   37.83643  1.000 19.61717 ?  61  LEU   B N   1 
ATOM   2744 C CA  . LEU   B 1 81  ? -14.34724 1.08456   38.02029  1.000 21.45340 ?  61  LEU   B CA  1 
ATOM   2745 C C   . LEU   B 1 81  ? -14.65245 0.87753   39.49813  1.000 23.78929 ?  61  LEU   B C   1 
ATOM   2746 O O   . LEU   B 1 81  ? -15.82044 0.72544   39.87341  1.000 23.85630 ?  61  LEU   B O   1 
ATOM   2747 C CB  . LEU   B 1 81  ? -14.09706 -0.25567  37.32771  1.000 21.80859 ?  61  LEU   B CB  1 
ATOM   2748 C CG  . LEU   B 1 81  ? -14.14259 -0.22058  35.79755  1.000 25.33710 ?  61  LEU   B CG  1 
ATOM   2749 C CD1 . LEU   B 1 81  ? -13.55947 -1.49260  35.20285  1.000 25.07929 ?  61  LEU   B CD1 1 
ATOM   2750 C CD2 . LEU   B 1 81  ? -15.56494 0.00077   35.31387  1.000 22.82623 ?  61  LEU   B CD2 1 
ATOM   2751 N N   . THR   B 1 82  ? -13.62139 0.87089   40.34759  1.000 24.37833 ?  62  THR   B N   1 
ATOM   2752 C CA  . THR   B 1 82  ? -13.85005 0.83437   41.78817  1.000 22.08460 ?  62  THR   B CA  1 
ATOM   2753 C C   . THR   B 1 82  ? -14.52380 2.11555   42.26556  1.000 23.24196 ?  62  THR   B C   1 
ATOM   2754 O O   . THR   B 1 82  ? -15.44100 2.06957   43.09465  1.000 22.38712 ?  62  THR   B O   1 
ATOM   2755 C CB  . THR   B 1 82  ? -12.52735 0.61106   42.52458  1.000 22.47881 ?  62  THR   B CB  1 
ATOM   2756 O OG1 . THR   B 1 82  ? -11.90476 -0.58641  42.04103  1.000 17.57287 ?  62  THR   B OG1 1 
ATOM   2757 C CG2 . THR   B 1 82  ? -12.75880 0.48727   44.02573  1.000 19.50047 ?  62  THR   B CG2 1 
ATOM   2758 N N   . ARG   B 1 83  ? -14.08704 3.26793   41.74766  1.000 21.07268 ?  63  ARG   B N   1 
ATOM   2759 C CA  . ARG   B 1 83  ? -14.75932 4.52281   42.06773  1.000 20.54775 ?  63  ARG   B CA  1 
ATOM   2760 C C   . ARG   B 1 83  ? -16.20697 4.50388   41.59624  1.000 22.27582 ?  63  ARG   B C   1 
ATOM   2761 O O   . ARG   B 1 83  ? -17.10727 4.96052   42.31084  1.000 27.07554 ?  63  ARG   B O   1 
ATOM   2762 C CB  . ARG   B 1 83  ? -14.00892 5.69803   41.43967  1.000 23.42394 ?  63  ARG   B CB  1 
ATOM   2763 C CG  . ARG   B 1 83  ? -12.95344 6.31445   42.33615  1.000 27.18634 ?  63  ARG   B CG  1 
ATOM   2764 C CD  . ARG   B 1 83  ? -12.91975 7.82961   42.18979  1.000 26.11951 ?  63  ARG   B CD  1 
ATOM   2765 N NE  . ARG   B 1 83  ? -12.69049 8.24737   40.81115  1.000 37.92041 ?  63  ARG   B NE  1 
ATOM   2766 C CZ  . ARG   B 1 83  ? -13.26978 9.29362   40.23714  1.000 36.38034 ?  63  ARG   B CZ  1 
ATOM   2767 N NH1 . ARG   B 1 83  ? -14.13247 10.05298  40.89291  1.000 38.37303 ?  63  ARG   B NH1 1 
ATOM   2768 N NH2 . ARG   B 1 83  ? -12.97226 9.58849   38.97478  1.000 29.00516 ?  63  ARG   B NH2 1 
ATOM   2769 N N   . LEU   B 1 84  ? -16.44874 3.97833   40.39204  1.000 23.64560 ?  64  LEU   B N   1 
ATOM   2770 C CA  . LEU   B 1 84  ? -17.81313 3.86343   39.88958  1.000 25.76825 ?  64  LEU   B CA  1 
ATOM   2771 C C   . LEU   B 1 84  ? -18.66102 2.95271   40.76717  1.000 28.69515 ?  64  LEU   B C   1 
ATOM   2772 O O   . LEU   B 1 84  ? -19.88597 3.11023   40.82135  1.000 27.85913 ?  64  LEU   B O   1 
ATOM   2773 C CB  . LEU   B 1 84  ? -17.79582 3.34865   38.44985  1.000 26.08164 ?  64  LEU   B CB  1 
ATOM   2774 C CG  . LEU   B 1 84  ? -17.38204 4.35181   37.37260  1.000 34.97593 ?  64  LEU   B CG  1 
ATOM   2775 C CD1 . LEU   B 1 84  ? -17.16879 3.65416   36.03934  1.000 33.60428 ?  64  LEU   B CD1 1 
ATOM   2776 C CD2 . LEU   B 1 84  ? -18.43262 5.44095   37.24010  1.000 32.35484 ?  64  LEU   B CD2 1 
ATOM   2777 N N   . ALA   B 1 85  ? -18.03282 2.00208   41.46439  1.000 29.35154 ?  65  ALA   B N   1 
ATOM   2778 C CA  . ALA   B 1 85  ? -18.78112 1.08677   42.31705  1.000 29.09564 ?  65  ALA   B CA  1 
ATOM   2779 C C   . ALA   B 1 85  ? -19.35726 1.77527   43.54409  1.000 25.85088 ?  65  ALA   B C   1 
ATOM   2780 O O   . ALA   B 1 85  ? -20.28281 1.23905   44.16217  1.000 32.37469 ?  65  ALA   B O   1 
ATOM   2781 C CB  . ALA   B 1 85  ? -17.89718 -0.08996  42.73027  1.000 23.50751 ?  65  ALA   B CB  1 
ATOM   2782 N N   . THR   B 1 86  ? -18.84168 2.94566   43.90340  1.000 26.81988 ?  66  THR   B N   1 
ATOM   2783 C CA  . THR   B 1 86  ? -19.38904 3.73265   44.99754  1.000 23.88287 ?  66  THR   B CA  1 
ATOM   2784 C C   . THR   B 1 86  ? -20.40265 4.76812   44.52706  1.000 31.37446 ?  66  THR   B C   1 
ATOM   2785 O O   . THR   B 1 86  ? -20.98657 5.46688   45.36128  1.000 38.42109 ?  66  THR   B O   1 
ATOM   2786 C CB  . THR   B 1 86  ? -18.25684 4.42303   45.76524  1.000 27.56260 ?  66  THR   B CB  1 
ATOM   2787 O OG1 . THR   B 1 86  ? -17.77939 5.54653   45.01434  1.000 29.61791 ?  66  THR   B OG1 1 
ATOM   2788 C CG2 . THR   B 1 86  ? -17.10877 3.45020   46.00077  1.000 21.52361 ?  66  THR   B CG2 1 
ATOM   2789 N N   . ASP   B 1 87  ? -20.62663 4.88153   43.21980  1.000 28.70190 ?  67  ASP   B N   1 
ATOM   2790 C CA  . ASP   B 1 87  ? -21.60830 5.81029   42.66995  1.000 26.99502 ?  67  ASP   B CA  1 
ATOM   2791 C C   . ASP   B 1 87  ? -22.94838 5.08774   42.59221  1.000 34.02548 ?  67  ASP   B C   1 
ATOM   2792 O O   . ASP   B 1 87  ? -23.14352 4.21658   41.73746  1.000 34.03863 ?  67  ASP   B O   1 
ATOM   2793 C CB  . ASP   B 1 87  ? -21.16341 6.31259   41.29816  1.000 27.19462 ?  67  ASP   B CB  1 
ATOM   2794 C CG  . ASP   B 1 87  ? -21.97212 7.50565   40.81589  1.000 33.45669 ?  67  ASP   B CG  1 
ATOM   2795 O OD1 . ASP   B 1 87  ? -23.15892 7.62769   41.18748  1.000 26.86832 ?  67  ASP   B OD1 1 
ATOM   2796 O OD2 . ASP   B 1 87  ? -21.41411 8.32719   40.05983  1.000 33.31013 ?  67  ASP   B OD2 1 
ATOM   2797 N N   . GLU   B 1 88  ? -23.87338 5.45093   43.48276  1.000 31.01604 ?  68  GLU   B N   1 
ATOM   2798 C CA  . GLU   B 1 88  ? -25.15943 4.77019   43.55340  1.000 29.42453 ?  68  GLU   B CA  1 
ATOM   2799 C C   . GLU   B 1 88  ? -26.12311 5.18809   42.45043  1.000 29.53413 ?  68  GLU   B C   1 
ATOM   2800 O O   . GLU   B 1 88  ? -27.20300 4.59761   42.34341  1.000 34.44449 ?  68  GLU   B O   1 
ATOM   2801 C CB  . GLU   B 1 88  ? -25.80404 5.00744   44.92003  1.000 34.69146 ?  68  GLU   B CB  1 
ATOM   2802 C CG  . GLU   B 1 88  ? -25.19846 4.17033   46.03465  1.000 38.08048 ?  68  GLU   B CG  1 
ATOM   2803 C CD  . GLU   B 1 88  ? -26.24518 3.49832   46.90141  1.000 50.14732 ?  68  GLU   B CD  1 
ATOM   2804 O OE1 . GLU   B 1 88  ? -26.06666 2.30603   47.23171  1.000 57.51607 ?  68  GLU   B OE1 1 
ATOM   2805 O OE2 . GLU   B 1 88  ? -27.24375 4.16045   47.25331  1.000 47.92874 ?  68  GLU   B OE2 1 
ATOM   2806 N N   . SER   B 1 89  ? -25.77085 6.18407   41.63444  1.000 27.06029 ?  69  SER   B N   1 
ATOM   2807 C CA  . SER   B 1 89  ? -26.59839 6.52730   40.48483  1.000 30.62822 ?  69  SER   B CA  1 
ATOM   2808 C C   . SER   B 1 89  ? -26.43713 5.53519   39.34246  1.000 30.74926 ?  69  SER   B C   1 
ATOM   2809 O O   . SER   B 1 89  ? -27.30852 5.46664   38.46886  1.000 27.12085 ?  69  SER   B O   1 
ATOM   2810 C CB  . SER   B 1 89  ? -26.27089 7.93894   39.99377  1.000 29.22945 ?  69  SER   B CB  1 
ATOM   2811 O OG  . SER   B 1 89  ? -24.99068 7.98723   39.38935  1.000 28.46558 ?  69  SER   B OG  1 
ATOM   2812 N N   . VAL   B 1 90  ? -25.34571 4.77692   39.32763  1.000 34.40102 ?  70  VAL   B N   1 
ATOM   2813 C CA  . VAL   B 1 90  ? -25.14080 3.69706   38.37150  1.000 33.26235 ?  70  VAL   B CA  1 
ATOM   2814 C C   . VAL   B 1 90  ? -25.50859 2.39312   39.06169  1.000 28.84381 ?  70  VAL   B C   1 
ATOM   2815 O O   . VAL   B 1 90  ? -24.89509 2.02125   40.06964  1.000 28.10782 ?  70  VAL   B O   1 
ATOM   2816 C CB  . VAL   B 1 90  ? -23.69255 3.66268   37.86032  1.000 33.56185 ?  70  VAL   B CB  1 
ATOM   2817 C CG1 . VAL   B 1 90  ? -23.48050 2.46518   36.94481  1.000 32.12668 ?  70  VAL   B CG1 1 
ATOM   2818 C CG2 . VAL   B 1 90  ? -23.35561 4.95662   37.13858  1.000 30.63100 ?  70  VAL   B CG2 1 
ATOM   2819 N N   . SER   B 1 91  ? -26.51383 1.70385   38.52841  1.000 28.94111 ?  71  SER   B N   1 
ATOM   2820 C CA  . SER   B 1 91  ? -26.94796 0.44603   39.11878  1.000 30.36837 ?  71  SER   B CA  1 
ATOM   2821 C C   . SER   B 1 91  ? -25.81800 -0.57595  39.08869  1.000 31.28862 ?  71  SER   B C   1 
ATOM   2822 O O   . SER   B 1 91  ? -24.90965 -0.50864  38.25476  1.000 31.70626 ?  71  SER   B O   1 
ATOM   2823 C CB  . SER   B 1 91  ? -28.16567 -0.10331  38.37372  1.000 32.39137 ?  71  SER   B CB  1 
ATOM   2824 O OG  . SER   B 1 91  ? -27.77276 -0.82554  37.22048  1.000 33.86693 ?  71  SER   B OG  1 
ATOM   2825 N N   . VAL   B 1 92  ? -25.87789 -1.52872  40.02301  1.000 32.07216 ?  72  VAL   B N   1 
ATOM   2826 C CA  . VAL   B 1 92  ? -24.88422 -2.59645  40.05628  1.000 28.72510 ?  72  VAL   B CA  1 
ATOM   2827 C C   . VAL   B 1 92  ? -24.92410 -3.39305  38.76164  1.000 33.49068 ?  72  VAL   B C   1 
ATOM   2828 O O   . VAL   B 1 92  ? -23.88340 -3.83582  38.25936  1.000 28.32630 ?  72  VAL   B O   1 
ATOM   2829 C CB  . VAL   B 1 92  ? -25.11240 -3.49912  41.28613  1.000 33.77883 ?  72  VAL   B CB  1 
ATOM   2830 C CG1 . VAL   B 1 92  ? -24.16016 -4.69358  41.26511  1.000 30.90096 ?  72  VAL   B CG1 1 
ATOM   2831 C CG2 . VAL   B 1 92  ? -24.95688 -2.69836  42.56978  1.000 23.85727 ?  72  VAL   B CG2 1 
ATOM   2832 N N   . GLU   B 1 93  ? -26.11737 -3.57075  38.18990  1.000 30.17104 ?  73  GLU   B N   1 
ATOM   2833 C CA  . GLU   B 1 93  ? -26.24174 -4.30371  36.93625  1.000 31.77039 ?  73  GLU   B CA  1 
ATOM   2834 C C   . GLU   B 1 93  ? -25.65364 -3.52608  35.76610  1.000 27.93029 ?  73  GLU   B C   1 
ATOM   2835 O O   . GLU   B 1 93  ? -25.08069 -4.12981  34.85295  1.000 22.34758 ?  73  GLU   B O   1 
ATOM   2836 C CB  . GLU   B 1 93  ? -27.70909 -4.64011  36.67541  1.000 34.30449 ?  73  GLU   B CB  1 
ATOM   2837 C CG  . GLU   B 1 93  ? -28.44645 -5.16121  37.90037  1.000 43.81972 ?  73  GLU   B CG  1 
ATOM   2838 C CD  . GLU   B 1 93  ? -29.21496 -4.07388  38.63046  1.000 49.05487 ?  73  GLU   B CD  1 
ATOM   2839 O OE1 . GLU   B 1 93  ? -30.26945 -3.63986  38.11963  1.000 51.36878 ?  73  GLU   B OE1 1 
ATOM   2840 O OE2 . GLU   B 1 93  ? -28.76281 -3.65144  39.71560  1.000 39.96922 ?  73  GLU   B OE2 1 
ATOM   2841 N N   . ASN   B 1 94  ? -25.78732 -2.19668  35.76737  1.000 27.05966 ?  74  ASN   B N   1 
ATOM   2842 C CA  . ASN   B 1 94  ? -25.15125 -1.39664  34.72556  1.000 28.13839 ?  74  ASN   B CA  1 
ATOM   2843 C C   . ASN   B 1 94  ? -23.63686 -1.38706  34.87652  1.000 21.71214 ?  74  ASN   B C   1 
ATOM   2844 O O   . ASN   B 1 94  ? -22.91522 -1.30303  33.87695  1.000 20.49001 ?  74  ASN   B O   1 
ATOM   2845 C CB  . ASN   B 1 94  ? -25.69223 0.03297   34.74701  1.000 31.01305 ?  74  ASN   B CB  1 
ATOM   2846 C CG  . ASN   B 1 94  ? -27.02731 0.16154   34.04338  1.000 31.53581 ?  74  ASN   B CG  1 
ATOM   2847 O OD1 . ASN   B 1 94  ? -27.55301 -0.81035  33.50168  1.000 37.65241 ?  74  ASN   B OD1 1 
ATOM   2848 N ND2 . ASN   B 1 94  ? -27.58407 1.36751   34.04732  1.000 34.01663 ?  74  ASN   B ND2 1 
ATOM   2849 N N   . LEU   B 1 95  ? -23.14019 -1.46836  36.11082  1.000 21.85094 ?  75  LEU   B N   1 
ATOM   2850 C CA  . LEU   B 1 95  ? -21.69972 -1.53378  36.33009  1.000 27.32783 ?  75  LEU   B CA  1 
ATOM   2851 C C   . LEU   B 1 95  ? -21.12840 -2.84903  35.82122  1.000 25.45908 ?  75  LEU   B C   1 
ATOM   2852 O O   . LEU   B 1 95  ? -20.10695 -2.86668  35.12340  1.000 19.06141 ?  75  LEU   B O   1 
ATOM   2853 C CB  . LEU   B 1 95  ? -21.39395 -1.36411  37.81383  1.000 28.87932 ?  75  LEU   B CB  1 
ATOM   2854 C CG  . LEU   B 1 95  ? -20.06982 -0.71687  38.20165  1.000 36.77824 ?  75  LEU   B CG  1 
ATOM   2855 C CD1 . LEU   B 1 95  ? -20.15420 -0.41112  39.65762  1.000 36.52233 ?  75  LEU   B CD1 1 
ATOM   2856 C CD2 . LEU   B 1 95  ? -18.87160 -1.61453  37.92157  1.000 33.36813 ?  75  LEU   B CD2 1 
ATOM   2857 N N   . LEU   B 1 96  ? -21.76251 -3.96575  36.18643  1.000 26.14949 ?  76  LEU   B N   1 
ATOM   2858 C CA  . LEU   B 1 96  ? -21.30380 -5.26385  35.70704  1.000 25.10198 ?  76  LEU   B CA  1 
ATOM   2859 C C   . LEU   B 1 96  ? -21.35653 -5.32873  34.18742  1.000 20.73282 ?  76  LEU   B C   1 
ATOM   2860 O O   . LEU   B 1 96  ? -20.50737 -5.96677  33.55469  1.000 20.96305 ?  76  LEU   B O   1 
ATOM   2861 C CB  . LEU   B 1 96  ? -22.14308 -6.37744  36.33211  1.000 30.60142 ?  76  LEU   B CB  1 
ATOM   2862 C CG  . LEU   B 1 96  ? -21.84344 -6.67513  37.80366  1.000 29.81105 ?  76  LEU   B CG  1 
ATOM   2863 C CD1 . LEU   B 1 96  ? -22.91366 -7.57325  38.40595  1.000 35.74194 ?  76  LEU   B CD1 1 
ATOM   2864 C CD2 . LEU   B 1 96  ? -20.46493 -7.30115  37.95583  1.000 29.08375 ?  76  LEU   B CD2 1 
ATOM   2865 N N   . THR   B 1 97  ? -22.34422 -4.66292  33.58404  1.000 25.22817 ?  77  THR   B N   1 
ATOM   2866 C CA  . THR   B 1 97  ? -22.36159 -4.52179  32.13266  1.000 26.42997 ?  77  THR   B CA  1 
ATOM   2867 C C   . THR   B 1 97  ? -21.15558 -3.72543  31.64939  1.000 23.85086 ?  77  THR   B C   1 
ATOM   2868 O O   . THR   B 1 97  ? -20.52920 -4.07920  30.64307  1.000 22.93453 ?  77  THR   B O   1 
ATOM   2869 C CB  . THR   B 1 97  ? -23.66164 -3.85109  31.68676  1.000 21.64118 ?  77  THR   B CB  1 
ATOM   2870 O OG1 . THR   B 1 97  ? -24.77636 -4.68455  32.03021  1.000 25.41481 ?  77  THR   B OG1 1 
ATOM   2871 C CG2 . THR   B 1 97  ? -23.65635 -3.61642  30.18360  1.000 25.37812 ?  77  THR   B CG2 1 
ATOM   2872 N N   . VAL   B 1 98  ? -20.80965 -2.65040  32.36149  1.000 19.89870 ?  78  VAL   B N   1 
ATOM   2873 C CA  . VAL   B 1 98  ? -19.64698 -1.84876  31.98693  1.000 23.33881 ?  78  VAL   B CA  1 
ATOM   2874 C C   . VAL   B 1 98  ? -18.37224 -2.67525  32.11278  1.000 21.38894 ?  78  VAL   B C   1 
ATOM   2875 O O   . VAL   B 1 98  ? -17.51943 -2.67577  31.21595  1.000 19.27999 ?  78  VAL   B O   1 
ATOM   2876 C CB  . VAL   B 1 98  ? -19.57928 -0.56884  32.84116  1.000 27.06560 ?  78  VAL   B CB  1 
ATOM   2877 C CG1 . VAL   B 1 98  ? -18.18365 0.03088   32.79683  1.000 19.38743 ?  78  VAL   B CG1 1 
ATOM   2878 C CG2 . VAL   B 1 98  ? -20.61398 0.44305   32.37124  1.000 25.16940 ?  78  VAL   B CG2 1 
ATOM   2879 N N   . PHE   B 1 99  ? -18.22974 -3.40117  33.22547  1.000 19.90187 ?  79  PHE   B N   1 
ATOM   2880 C CA  . PHE   B 1 99  ? -17.03391 -4.21224  33.43493  1.000 21.61591 ?  79  PHE   B CA  1 
ATOM   2881 C C   . PHE   B 1 99  ? -16.91459 -5.29821  32.37090  1.000 19.46648 ?  79  PHE   B C   1 
ATOM   2882 O O   . PHE   B 1 99  ? -15.84938 -5.48100  31.77229  1.000 20.33773 ?  79  PHE   B O   1 
ATOM   2883 C CB  . PHE   B 1 99  ? -17.05335 -4.82145  34.84082  1.000 20.09262 ?  79  PHE   B CB  1 
ATOM   2884 C CG  . PHE   B 1 99  ? -15.83423 -5.64542  35.16723  1.000 19.96149 ?  79  PHE   B CG  1 
ATOM   2885 C CD1 . PHE   B 1 99  ? -15.75931 -6.98187  34.80337  1.000 22.37014 ?  79  PHE   B CD1 1 
ATOM   2886 C CD2 . PHE   B 1 99  ? -14.75907 -5.07818  35.83112  1.000 21.12933 ?  79  PHE   B CD2 1 
ATOM   2887 C CE1 . PHE   B 1 99  ? -14.64000 -7.73540  35.09735  1.000 21.52191 ?  79  PHE   B CE1 1 
ATOM   2888 C CE2 . PHE   B 1 99  ? -13.63590 -5.82733  36.12852  1.000 19.12240 ?  79  PHE   B CE2 1 
ATOM   2889 C CZ  . PHE   B 1 99  ? -13.57659 -7.15762  35.76028  1.000 21.27301 ?  79  PHE   B CZ  1 
ATOM   2890 N N   . ARG   B 1 100 ? -18.00572 -6.02608  32.11656  1.000 23.19891 ?  80  ARG   B N   1 
ATOM   2891 C CA  . ARG   B 1 100 ? -17.97264 -7.12385  31.15609  1.000 20.08250 ?  80  ARG   B CA  1 
ATOM   2892 C C   . ARG   B 1 100 ? -17.60164 -6.66078  29.75168  1.000 23.02037 ?  80  ARG   B C   1 
ATOM   2893 O O   . ARG   B 1 100 ? -17.12465 -7.47443  28.95252  1.000 20.48905 ?  80  ARG   B O   1 
ATOM   2894 C CB  . ARG   B 1 100 ? -19.32801 -7.83960  31.12410  1.000 19.91373 ?  80  ARG   B CB  1 
ATOM   2895 C CG  . ARG   B 1 100 ? -19.55913 -8.80404  32.27424  1.000 25.15071 ?  80  ARG   B CG  1 
ATOM   2896 C CD  . ARG   B 1 100 ? -21.03867 -9.07708  32.45224  1.000 28.41498 ?  80  ARG   B CD  1 
ATOM   2897 N NE  . ARG   B 1 100 ? -21.33919 -9.61962  33.77013  1.000 33.46292 ?  80  ARG   B NE  1 
ATOM   2898 C CZ  . ARG   B 1 100 ? -22.51843 -9.51374  34.36508  1.000 36.30307 ?  80  ARG   B CZ  1 
ATOM   2899 N NH1 . ARG   B 1 100 ? -23.53356 -8.89941  33.78003  1.000 33.77337 ?  80  ARG   B NH1 1 
ATOM   2900 N NH2 . ARG   B 1 100 ? -22.68386 -10.03802 35.57580  1.000 32.08120 ?  80  ARG   B NH2 1 
ATOM   2901 N N   . THR   B 1 101 ? -17.80825 -5.38064  29.43194  1.000 16.90601 ?  81  THR   B N   1 
ATOM   2902 C CA  . THR   B 1 101 ? -17.45821 -4.85055  28.11889  1.000 25.19383 ?  81  THR   B CA  1 
ATOM   2903 C C   . THR   B 1 101 ? -16.02024 -4.34578  28.06171  1.000 21.46856 ?  81  THR   B C   1 
ATOM   2904 O O   . THR   B 1 101 ? -15.32452 -4.57173  27.06586  1.000 19.99312 ?  81  THR   B O   1 
ATOM   2905 C CB  . THR   B 1 101 ? -18.41533 -3.71367  27.72712  1.000 28.55252 ?  81  THR   B CB  1 
ATOM   2906 O OG1 . THR   B 1 101 ? -19.77586 -4.09815  27.97997  1.000 27.08671 ?  81  THR   B OG1 1 
ATOM   2907 C CG2 . THR   B 1 101 ? -18.25723 -3.35777  26.25222  1.000 26.63182 ?  81  THR   B CG2 1 
ATOM   2908 N N   . LEU   B 1 102 ? -15.56025 -3.67689  29.11844  1.000 23.97122 ?  82  LEU   B N   1 
ATOM   2909 C CA  . LEU   B 1 102 ? -14.24175 -3.05506  29.14108  1.000 24.72395 ?  82  LEU   B CA  1 
ATOM   2910 C C   . LEU   B 1 102 ? -13.13040 -4.01159  29.55590  1.000 20.51750 ?  82  LEU   B C   1 
ATOM   2911 O O   . LEU   B 1 102 ? -11.98227 -3.83710  29.12860  1.000 23.61479 ?  82  LEU   B O   1 
ATOM   2912 C CB  . LEU   B 1 102 ? -14.25052 -1.85416  30.09625  1.000 24.52441 ?  82  LEU   B CB  1 
ATOM   2913 C CG  . LEU   B 1 102 ? -12.93368 -1.09223  30.28629  1.000 33.88644 ?  82  LEU   B CG  1 
ATOM   2914 C CD1 . LEU   B 1 102 ? -12.49291 -0.48553  28.96569  1.000 21.21942 ?  82  LEU   B CD1 1 
ATOM   2915 C CD2 . LEU   B 1 102 ? -13.06267 -0.02963  31.36482  1.000 28.05921 ?  82  LEU   B CD2 1 
ATOM   2916 N N   . ASP   B 1 103 ? -13.44208 -5.01846  30.37611  1.000 18.52238 ?  83  ASP   B N   1 
ATOM   2917 C CA  . ASP   B 1 103 ? -12.38131 -5.85640  30.93611  1.000 19.31890 ?  83  ASP   B CA  1 
ATOM   2918 C C   . ASP   B 1 103 ? -11.74529 -6.79603  29.91780  1.000 20.07578 ?  83  ASP   B C   1 
ATOM   2919 O O   . ASP   B 1 103 ? -10.50407 -6.82318  29.83670  1.000 19.99744 ?  83  ASP   B O   1 
ATOM   2920 C CB  . ASP   B 1 103 ? -12.91459 -6.62885  32.14584  1.000 17.86863 ?  83  ASP   B CB  1 
ATOM   2921 C CG  . ASP   B 1 103 ? -11.86396 -7.54036  32.76422  1.000 18.84582 ?  83  ASP   B CG  1 
ATOM   2922 O OD1 . ASP   B 1 103 ? -11.09280 -7.07232  33.62807  1.000 20.58311 ?  83  ASP   B OD1 1 
ATOM   2923 O OD2 . ASP   B 1 103 ? -11.80720 -8.72676  32.38006  1.000 22.02135 ?  83  ASP   B OD2 1 
ATOM   2924 N N   . PRO   B 1 104 ? -12.49487 -7.58717  29.12976  1.000 20.36202 ?  84  PRO   B N   1 
ATOM   2925 C CA  . PRO   B 1 104 ? -11.85587 -8.70479  28.40385  1.000 20.17639 ?  84  PRO   B CA  1 
ATOM   2926 C C   . PRO   B 1 104 ? -10.70354 -8.31018  27.49397  1.000 19.22460 ?  84  PRO   B C   1 
ATOM   2927 O O   . PRO   B 1 104 ? -9.71009  -9.04377  27.42622  1.000 20.18827 ?  84  PRO   B O   1 
ATOM   2928 C CB  . PRO   B 1 104 ? -13.01986 -9.30459  27.60194  1.000 18.28391 ?  84  PRO   B CB  1 
ATOM   2929 C CG  . PRO   B 1 104 ? -14.22483 -8.94968  28.37749  1.000 28.47461 ?  84  PRO   B CG  1 
ATOM   2930 C CD  . PRO   B 1 104 ? -13.95126 -7.57254  28.90025  1.000 21.67645 ?  84  PRO   B CD  1 
ATOM   2931 N N   . ILE   B 1 105 ? -10.80015 -7.18209  26.78552  1.000 21.69659 ?  85  ILE   B N   1 
ATOM   2932 C CA  . ILE   B 1 105 ? -9.72386  -6.80338  25.87191  1.000 16.71001 ?  85  ILE   B CA  1 
ATOM   2933 C C   . ILE   B 1 105 ? -8.40923  -6.61993  26.62083  1.000 19.01042 ?  85  ILE   B C   1 
ATOM   2934 O O   . ILE   B 1 105 ? -7.32952  -6.86772  26.06851  1.000 24.75319 ?  85  ILE   B O   1 
ATOM   2935 C CB  . ILE   B 1 105 ? -10.11026 -5.53943  25.07708  1.000 21.71335 ?  85  ILE   B CB  1 
ATOM   2936 C CG1 . ILE   B 1 105 ? -9.05838  -5.24679  24.00637  1.000 26.61690 ?  85  ILE   B CG1 1 
ATOM   2937 C CG2 . ILE   B 1 105 ? -10.28082 -4.34362  26.00305  1.000 21.07681 ?  85  ILE   B CG2 1 
ATOM   2938 C CD1 . ILE   B 1 105 ? -8.87592  -6.37061  23.00981  1.000 23.12884 ?  85  ILE   B CD1 1 
ATOM   2939 N N   . TYR   B 1 106 ? -8.47355  -6.21004  27.88819  1.000 18.06525 ?  86  TYR   B N   1 
ATOM   2940 C CA  . TYR   B 1 106 ? -7.26581  -6.04982  28.69001  1.000 19.30277 ?  86  TYR   B CA  1 
ATOM   2941 C C   . TYR   B 1 106 ? -6.83781  -7.36825  29.32559  1.000 19.73337 ?  86  TYR   B C   1 
ATOM   2942 O O   . TYR   B 1 106 ? -5.67336  -7.76938  29.21932  1.000 17.69632 ?  86  TYR   B O   1 
ATOM   2943 C CB  . TYR   B 1 106 ? -7.49571  -5.00127  29.77835  1.000 16.34162 ?  86  TYR   B CB  1 
ATOM   2944 C CG  . TYR   B 1 106 ? -7.31939  -3.56647  29.33867  1.000 20.97609 ?  86  TYR   B CG  1 
ATOM   2945 C CD1 . TYR   B 1 106 ? -8.37138  -2.86290  28.76953  1.000 16.36709 ?  86  TYR   B CD1 1 
ATOM   2946 C CD2 . TYR   B 1 106 ? -6.10963  -2.90690  29.51772  1.000 20.86928 ?  86  TYR   B CD2 1 
ATOM   2947 C CE1 . TYR   B 1 106 ? -8.22115  -1.55057  28.37498  1.000 20.28513 ?  86  TYR   B CE1 1 
ATOM   2948 C CE2 . TYR   B 1 106 ? -5.94966  -1.59055  29.12689  1.000 18.90395 ?  86  TYR   B CE2 1 
ATOM   2949 C CZ  . TYR   B 1 106 ? -7.01057  -0.91790  28.55660  1.000 21.74275 ?  86  TYR   B CZ  1 
ATOM   2950 O OH  . TYR   B 1 106 ? -6.86485  0.39192   28.16477  1.000 20.10752 ?  86  TYR   B OH  1 
ATOM   2951 N N   . SER   B 1 107 ? -7.77290  -8.05538  29.98859  1.000 20.66858 ?  87  SER   B N   1 
ATOM   2952 C CA  . SER   B 1 107 ? -7.40696  -9.18348  30.84071  1.000 19.45769 ?  87  SER   B CA  1 
ATOM   2953 C C   . SER   B 1 107 ? -7.01023  -10.40784 30.02439  1.000 25.05269 ?  87  SER   B C   1 
ATOM   2954 O O   . SER   B 1 107 ? -6.05726  -11.11083 30.38058  1.000 21.00248 ?  87  SER   B O   1 
ATOM   2955 C CB  . SER   B 1 107 ? -8.55939  -9.52087  31.78578  1.000 14.66366 ?  87  SER   B CB  1 
ATOM   2956 O OG  . SER   B 1 107 ? -9.72093  -9.88937  31.06578  1.000 19.01766 ?  87  SER   B OG  1 
ATOM   2957 N N   . THR   B 1 108 ? -7.72970  -10.69079 28.93497  1.000 23.40532 ?  88  THR   B N   1 
ATOM   2958 C CA  . THR   B 1 108 ? -7.38605  -11.85611 28.12356  1.000 23.29926 ?  88  THR   B CA  1 
ATOM   2959 C C   . THR   B 1 108 ? -5.99682  -11.71767 27.51162  1.000 24.53571 ?  88  THR   B C   1 
ATOM   2960 O O   . THR   B 1 108 ? -5.24588  -12.69652 27.43821  1.000 24.80755 ?  88  THR   B O   1 
ATOM   2961 C CB  . THR   B 1 108 ? -8.43675  -12.08718 27.03605  1.000 23.94154 ?  88  THR   B CB  1 
ATOM   2962 O OG1 . THR   B 1 108 ? -8.34700  -11.05609 26.04263  1.000 36.98306 ?  88  THR   B OG1 1 
ATOM   2963 C CG2 . THR   B 1 108 ? -9.83888  -12.13312 27.63955  1.000 20.19393 ?  88  THR   B CG2 1 
ATOM   2964 N N   . PHE   B 1 109 ? -5.62839  -10.51080 27.07692  1.000 21.24957 ?  89  PHE   B N   1 
ATOM   2965 C CA  . PHE   B 1 109 ? -4.26304  -10.29135 26.60780  1.000 21.86901 ?  89  PHE   B CA  1 
ATOM   2966 C C   . PHE   B 1 109 ? -3.25899  -10.54447 27.72590  1.000 21.20786 ?  89  PHE   B C   1 
ATOM   2967 O O   . PHE   B 1 109 ? -2.22824  -11.19515 27.51760  1.000 19.11802 ?  89  PHE   B O   1 
ATOM   2968 C CB  . PHE   B 1 109 ? -4.11183  -8.87126  26.05512  1.000 20.75397 ?  89  PHE   B CB  1 
ATOM   2969 C CG  . PHE   B 1 109 ? -2.72652  -8.55812  25.55579  1.000 23.08026 ?  89  PHE   B CG  1 
ATOM   2970 C CD1 . PHE   B 1 109 ? -1.74967  -8.08815  26.42118  1.000 20.14211 ?  89  PHE   B CD1 1 
ATOM   2971 C CD2 . PHE   B 1 109 ? -2.39991  -8.74218  24.22247  1.000 23.36769 ?  89  PHE   B CD2 1 
ATOM   2972 C CE1 . PHE   B 1 109 ? -0.47605  -7.80971  25.96698  1.000 28.08914 ?  89  PHE   B CE1 1 
ATOM   2973 C CE2 . PHE   B 1 109 ? -1.12695  -8.46026  23.76157  1.000 26.88962 ?  89  PHE   B CE2 1 
ATOM   2974 C CZ  . PHE   B 1 109 ? -0.16482  -7.99293  24.63505  1.000 23.47104 ?  89  PHE   B CZ  1 
ATOM   2975 N N   . LEU   B 1 110 ? -3.54672  -10.03359 28.92523  1.000 23.16185 ?  90  LEU   B N   1 
ATOM   2976 C CA  . LEU   B 1 110 ? -2.62389  -10.20299 30.04108  1.000 23.08709 ?  90  LEU   B CA  1 
ATOM   2977 C C   . LEU   B 1 110 ? -2.54933  -11.65586 30.49298  1.000 19.56970 ?  90  LEU   B C   1 
ATOM   2978 O O   . LEU   B 1 110 ? -1.49713  -12.10364 30.96110  1.000 22.21880 ?  90  LEU   B O   1 
ATOM   2979 C CB  . LEU   B 1 110 ? -3.03741  -9.29731  31.20134  1.000 23.69200 ?  90  LEU   B CB  1 
ATOM   2980 C CG  . LEU   B 1 110 ? -2.75574  -7.80520  31.00782  1.000 25.37529 ?  90  LEU   B CG  1 
ATOM   2981 C CD1 . LEU   B 1 110 ? -3.46499  -6.97039  32.06523  1.000 13.21653 ?  90  LEU   B CD1 1 
ATOM   2982 C CD2 . LEU   B 1 110 ? -1.25847  -7.53467  31.02197  1.000 20.89926 ?  90  LEU   B CD2 1 
ATOM   2983 N N   . GLY   B 1 111 ? -3.64496  -12.40514 30.35849  1.000 21.79335 ?  91  GLY   B N   1 
ATOM   2984 C CA  . GLY   B 1 111 ? -3.61899  -13.80915 30.72451  1.000 26.10347 ?  91  GLY   B CA  1 
ATOM   2985 C C   . GLY   B 1 111 ? -2.72891  -14.64153 29.82851  1.000 23.18249 ?  91  GLY   B C   1 
ATOM   2986 O O   . GLY   B 1 111 ? -2.10027  -15.59873 30.29036  1.000 28.49681 ?  91  GLY   B O   1 
ATOM   2987 N N   . TYR   B 1 112 ? -2.65358  -14.29194 28.54636  1.000 24.66563 ?  92  TYR   B N   1 
ATOM   2988 C CA  . TYR   B 1 112 ? -1.79256  -15.00437 27.61425  1.000 26.76108 ?  92  TYR   B CA  1 
ATOM   2989 C C   . TYR   B 1 112 ? -0.37628  -14.44429 27.55764  1.000 25.97602 ?  92  TYR   B C   1 
ATOM   2990 O O   . TYR   B 1 112 ? 0.47350   -15.02900 26.87750  1.000 29.31804 ?  92  TYR   B O   1 
ATOM   2991 C CB  . TYR   B 1 112 ? -2.39759  -14.98444 26.20406  1.000 25.85924 ?  92  TYR   B CB  1 
ATOM   2992 C CG  . TYR   B 1 112 ? -3.63265  -15.84586 26.05359  1.000 32.75444 ?  92  TYR   B CG  1 
ATOM   2993 C CD1 . TYR   B 1 112 ? -3.54157  -17.23124 25.99870  1.000 37.06341 ?  92  TYR   B CD1 1 
ATOM   2994 C CD2 . TYR   B 1 112 ? -4.89282  -15.27070 25.97378  1.000 33.25996 ?  92  TYR   B CD2 1 
ATOM   2995 C CE1 . TYR   B 1 112 ? -4.67454  -18.01599 25.86807  1.000 42.71011 ?  92  TYR   B CE1 1 
ATOM   2996 C CE2 . TYR   B 1 112 ? -6.02792  -16.04465 25.84551  1.000 32.73575 ?  92  TYR   B CE2 1 
ATOM   2997 C CZ  . TYR   B 1 112 ? -5.91373  -17.41620 25.79208  1.000 37.70270 ?  92  TYR   B CZ  1 
ATOM   2998 O OH  . TYR   B 1 112 ? -7.04309  -18.19024 25.66243  1.000 30.59386 ?  92  TYR   B OH  1 
ATOM   2999 N N   . ASN   B 1 113 ? -0.09332  -13.34070 28.25396  1.000 24.36990 ?  93  ASN   B N   1 
ATOM   3000 C CA  . ASN   B 1 113 ? 1.21202   -12.69275 28.18417  1.000 23.55755 ?  93  ASN   B CA  1 
ATOM   3001 C C   . ASN   B 1 113 ? 1.85881   -12.54843 29.55943  1.000 23.77590 ?  93  ASN   B C   1 
ATOM   3002 O O   . ASN   B 1 113 ? 2.57214   -11.57528 29.81757  1.000 32.68989 ?  93  ASN   B O   1 
ATOM   3003 C CB  . ASN   B 1 113 ? 1.10339   -11.32837 27.50247  1.000 25.96855 ?  93  ASN   B CB  1 
ATOM   3004 C CG  . ASN   B 1 113 ? 1.17996   -11.42501 25.98853  1.000 26.69295 ?  93  ASN   B CG  1 
ATOM   3005 O OD1 . ASN   B 1 113 ? 2.26799   -11.43302 25.41120  1.000 30.61494 ?  93  ASN   B OD1 1 
ATOM   3006 N ND2 . ASN   B 1 113 ? 0.02371   -11.50303 25.33846  1.000 22.55582 ?  93  ASN   B ND2 1 
ATOM   3007 N N   . GLY   B 1 114 ? 1.62108   -13.50199 30.45644  1.000 27.90607 ?  94  GLY   B N   1 
ATOM   3008 C CA  . GLY   B 1 114 ? 2.34653   -13.50290 31.71253  1.000 25.51490 ?  94  GLY   B CA  1 
ATOM   3009 C C   . GLY   B 1 114 ? 1.52378   -13.55512 32.98405  1.000 27.22774 ?  94  GLY   B C   1 
ATOM   3010 O O   . GLY   B 1 114 ? 2.02958   -14.00217 34.01631  1.000 29.76246 ?  94  GLY   B O   1 
ATOM   3011 N N   . PHE   B 1 115 ? 0.26627   -13.10890 32.94006  1.000 21.45555 ?  95  PHE   B N   1 
ATOM   3012 C CA  . PHE   B 1 115 ? -0.58656  -13.01560 34.12484  1.000 21.04740 ?  95  PHE   B CA  1 
ATOM   3013 C C   . PHE   B 1 115 ? -1.82834  -13.88865 33.95788  1.000 23.44855 ?  95  PHE   B C   1 
ATOM   3014 O O   . PHE   B 1 115 ? -2.94267  -13.36938 33.80536  1.000 22.24541 ?  95  PHE   B O   1 
ATOM   3015 C CB  . PHE   B 1 115 ? -1.00416  -11.57049 34.39835  1.000 29.13214 ?  95  PHE   B CB  1 
ATOM   3016 C CG  . PHE   B 1 115 ? 0.11753   -10.57076 34.30422  1.000 26.41160 ?  95  PHE   B CG  1 
ATOM   3017 C CD1 . PHE   B 1 115 ? 0.43996   -9.97770  33.09319  1.000 28.68832 ?  95  PHE   B CD1 1 
ATOM   3018 C CD2 . PHE   B 1 115 ? 0.83439   -10.20714 35.43278  1.000 28.04330 ?  95  PHE   B CD2 1 
ATOM   3019 C CE1 . PHE   B 1 115 ? 1.46435   -9.05158  33.00813  1.000 24.54145 ?  95  PHE   B CE1 1 
ATOM   3020 C CE2 . PHE   B 1 115 ? 1.85965   -9.28137  35.35419  1.000 23.52656 ?  95  PHE   B CE2 1 
ATOM   3021 C CZ  . PHE   B 1 115 ? 2.17251   -8.70151  34.14118  1.000 23.78221 ?  95  PHE   B CZ  1 
ATOM   3022 N N   . PRO   B 1 116 ? -1.68196  -15.21800 33.99881  1.000 25.22229 ?  96  PRO   B N   1 
ATOM   3023 C CA  . PRO   B 1 116 ? -2.88078  -16.06674 33.91254  1.000 21.66173 ?  96  PRO   B CA  1 
ATOM   3024 C C   . PRO   B 1 116 ? -3.77961  -15.95850 35.13039  1.000 22.53720 ?  96  PRO   B C   1 
ATOM   3025 O O   . PRO   B 1 116 ? -5.00070  -16.10186 34.99516  1.000 22.74628 ?  96  PRO   B O   1 
ATOM   3026 C CB  . PRO   B 1 116 ? -2.30096  -17.47972 33.76164  1.000 22.69867 ?  96  PRO   B CB  1 
ATOM   3027 C CG  . PRO   B 1 116 ? -0.96754  -17.39293 34.41658  1.000 21.92736 ?  96  PRO   B CG  1 
ATOM   3028 C CD  . PRO   B 1 116 ? -0.45249  -16.02832 34.05742  1.000 30.08479 ?  96  PRO   B CD  1 
ATOM   3029 N N   . VAL   B 1 117 ? -3.21582  -15.71099 36.31501  1.000 18.35348 ?  97  VAL   B N   1 
ATOM   3030 C CA  . VAL   B 1 117 ? -4.03291  -15.60193 37.52001  1.000 19.09057 ?  97  VAL   B CA  1 
ATOM   3031 C C   . VAL   B 1 117 ? -4.85890  -14.32101 37.49307  1.000 24.79945 ?  97  VAL   B C   1 
ATOM   3032 O O   . VAL   B 1 117 ? -6.00706  -14.29674 37.95443  1.000 20.77116 ?  97  VAL   B O   1 
ATOM   3033 C CB  . VAL   B 1 117 ? -3.14287  -15.68416 38.77456  1.000 22.11395 ?  97  VAL   B CB  1 
ATOM   3034 C CG1 . VAL   B 1 117 ? -3.96870  -15.48759 40.03848  1.000 25.02926 ?  97  VAL   B CG1 1 
ATOM   3035 C CG2 . VAL   B 1 117 ? -2.41305  -17.01991 38.81675  1.000 22.40733 ?  97  VAL   B CG2 1 
ATOM   3036 N N   . LEU   B 1 118 ? -4.29356  -13.23944 36.95052  1.000 22.12802 ?  98  LEU   B N   1 
ATOM   3037 C CA  . LEU   B 1 118 ? -5.03754  -11.98817 36.83816  1.000 21.97346 ?  98  LEU   B CA  1 
ATOM   3038 C C   . LEU   B 1 118 ? -6.27018  -12.16284 35.95847  1.000 20.90613 ?  98  LEU   B C   1 
ATOM   3039 O O   . LEU   B 1 118 ? -7.38244  -11.78775 36.34662  1.000 19.71644 ?  98  LEU   B O   1 
ATOM   3040 C CB  . LEU   B 1 118 ? -4.12380  -10.88443 36.29560  1.000 24.77536 ?  98  LEU   B CB  1 
ATOM   3041 C CG  . LEU   B 1 118 ? -4.72771  -9.53156  35.89906  1.000 24.80839 ?  98  LEU   B CG  1 
ATOM   3042 C CD1 . LEU   B 1 118 ? -3.73081  -8.42337  36.17354  1.000 27.38961 ?  98  LEU   B CD1 1 
ATOM   3043 C CD2 . LEU   B 1 118 ? -5.13692  -9.49899  34.42887  1.000 20.12821 ?  98  LEU   B CD2 1 
ATOM   3044 N N   . ALA   B 1 119 ? -6.09072  -12.73426 34.76478  1.000 22.35306 ?  99  ALA   B N   1 
ATOM   3045 C CA  . ALA   B 1 119 ? -7.22988  -12.97427 33.88556  1.000 23.35105 ?  99  ALA   B CA  1 
ATOM   3046 C C   . ALA   B 1 119 ? -8.20986  -13.96575 34.49808  1.000 25.75563 ?  99  ALA   B C   1 
ATOM   3047 O O   . ALA   B 1 119 ? -9.42024  -13.86738 34.26366  1.000 25.46314 ?  99  ALA   B O   1 
ATOM   3048 C CB  . ALA   B 1 119 ? -6.74705  -13.47339 32.52391  1.000 20.84803 ?  99  ALA   B CB  1 
ATOM   3049 N N   . GLU   B 1 120 ? -7.70799  -14.92424 35.28118  1.000 24.72452 ?  100 GLU   B N   1 
ATOM   3050 C CA  . GLU   B 1 120 ? -8.58893  -15.86522 35.96493  1.000 20.76638 ?  100 GLU   B CA  1 
ATOM   3051 C C   . GLU   B 1 120 ? -9.50883  -15.14627 36.94326  1.000 22.99000 ?  100 GLU   B C   1 
ATOM   3052 O O   . GLU   B 1 120 ? -10.71055 -15.43334 37.00562  1.000 21.03158 ?  100 GLU   B O   1 
ATOM   3053 C CB  . GLU   B 1 120 ? -7.75243  -16.92360 36.68505  1.000 26.60910 ?  100 GLU   B CB  1 
ATOM   3054 C CG  . GLU   B 1 120 ? -8.43650  -17.58471 37.86701  1.000 26.05352 ?  100 GLU   B CG  1 
ATOM   3055 C CD  . GLU   B 1 120 ? -7.49778  -18.50300 38.62265  1.000 24.13814 ?  100 GLU   B CD  1 
ATOM   3056 O OE1 . GLU   B 1 120 ? -6.29656  -18.52799 38.28275  1.000 22.67095 ?  100 GLU   B OE1 1 
ATOM   3057 O OE2 . GLU   B 1 120 ? -7.95334  -19.19492 39.55679  1.000 17.27751 ?  100 GLU   B OE2 1 
ATOM   3058 N N   . TYR   B 1 121 ? -8.96625  -14.19686 37.70638  1.000 24.94760 ?  101 TYR   B N   1 
ATOM   3059 C CA  . TYR   B 1 121 ? -9.77370  -13.47602 38.67995  1.000 22.70503 ?  101 TYR   B CA  1 
ATOM   3060 C C   . TYR   B 1 121 ? -10.53208 -12.30815 38.06968  1.000 21.29764 ?  101 TYR   B C   1 
ATOM   3061 O O   . TYR   B 1 121 ? -11.52044 -11.85872 38.65892  1.000 21.29815 ?  101 TYR   B O   1 
ATOM   3062 C CB  . TYR   B 1 121 ? -8.89670  -12.99019 39.83337  1.000 21.92200 ?  101 TYR   B CB  1 
ATOM   3063 C CG  . TYR   B 1 121 ? -8.70743  -14.05484 40.88167  1.000 23.69051 ?  101 TYR   B CG  1 
ATOM   3064 C CD1 . TYR   B 1 121 ? -9.59246  -14.17438 41.94442  1.000 21.19826 ?  101 TYR   B CD1 1 
ATOM   3065 C CD2 . TYR   B 1 121 ? -7.66732  -14.96787 40.78705  1.000 21.29468 ?  101 TYR   B CD2 1 
ATOM   3066 C CE1 . TYR   B 1 121 ? -9.43270  -15.15939 42.89669  1.000 23.23236 ?  101 TYR   B CE1 1 
ATOM   3067 C CE2 . TYR   B 1 121 ? -7.49892  -15.95656 41.73416  1.000 21.04040 ?  101 TYR   B CE2 1 
ATOM   3068 C CZ  . TYR   B 1 121 ? -8.38445  -16.04717 42.78712  1.000 23.93947 ?  101 TYR   B CZ  1 
ATOM   3069 O OH  . TYR   B 1 121 ? -8.22265  -17.03147 43.73225  1.000 25.74974 ?  101 TYR   B OH  1 
ATOM   3070 N N   . ALA   B 1 122 ? -10.09999 -11.81151 36.90847  1.000 21.84327 ?  102 ALA   B N   1 
ATOM   3071 C CA  . ALA   B 1 122 ? -10.88456 -10.80123 36.20746  1.000 23.18265 ?  102 ALA   B CA  1 
ATOM   3072 C C   . ALA   B 1 122 ? -12.26016 -11.34060 35.84066  1.000 21.26743 ?  102 ALA   B C   1 
ATOM   3073 O O   . ALA   B 1 122 ? -13.25746 -10.61148 35.89352  1.000 24.87050 ?  102 ALA   B O   1 
ATOM   3074 C CB  . ALA   B 1 122 ? -10.14157 -10.32855 34.95876  1.000 21.73048 ?  102 ALA   B CB  1 
ATOM   3075 N N   . GLN   B 1 123 ? -12.33269 -12.62113 35.47092  1.000 21.30832 ?  103 GLN   B N   1 
ATOM   3076 C CA  . GLN   B 1 123 ? -13.62282 -13.23830 35.18354  1.000 23.12845 ?  103 GLN   B CA  1 
ATOM   3077 C C   . GLN   B 1 123 ? -14.49662 -13.29489 36.43062  1.000 21.67717 ?  103 GLN   B C   1 
ATOM   3078 O O   . GLN   B 1 123 ? -15.70716 -13.05098 36.36251  1.000 23.32042 ?  103 GLN   B O   1 
ATOM   3079 C CB  . GLN   B 1 123 ? -13.41403 -14.64161 34.61519  1.000 27.02581 ?  103 GLN   B CB  1 
ATOM   3080 C CG  . GLN   B 1 123 ? -12.74427 -14.67850 33.25359  1.000 30.58138 ?  103 GLN   B CG  1 
ATOM   3081 C CD  . GLN   B 1 123 ? -12.81050 -16.05326 32.62104  1.000 40.09070 ?  103 GLN   B CD  1 
ATOM   3082 O OE1 . GLN   B 1 123 ? -11.78365 -16.66329 32.32272  1.000 44.30245 ?  103 GLN   B OE1 1 
ATOM   3083 N NE2 . GLN   B 1 123 ? -14.02396 -16.55286 32.41996  1.000 42.69843 ?  103 GLN   B NE2 1 
ATOM   3084 N N   . ARG   B 1 124 ? -13.89951 -13.61280 37.58217  1.000 24.40227 ?  104 ARG   B N   1 
ATOM   3085 C CA  . ARG   B 1 124 ? -14.67730 -13.72297 38.81172  1.000 24.73930 ?  104 ARG   B CA  1 
ATOM   3086 C C   . ARG   B 1 124 ? -15.15700 -12.36273 39.30259  1.000 25.32083 ?  104 ARG   B C   1 
ATOM   3087 O O   . ARG   B 1 124 ? -16.16819 -12.28307 40.01001  1.000 28.30478 ?  104 ARG   B O   1 
ATOM   3088 C CB  . ARG   B 1 124 ? -13.85342 -14.42613 39.89067  1.000 26.09104 ?  104 ARG   B CB  1 
ATOM   3089 C CG  . ARG   B 1 124 ? -13.75937 -15.92933 39.69262  1.000 25.53801 ?  104 ARG   B CG  1 
ATOM   3090 C CD  . ARG   B 1 124 ? -12.71781 -16.56308 40.60053  1.000 27.78521 ?  104 ARG   B CD  1 
ATOM   3091 N NE  . ARG   B 1 124 ? -13.01419 -16.37917 42.01628  1.000 26.56610 ?  104 ARG   B NE  1 
ATOM   3092 C CZ  . ARG   B 1 124 ? -12.39556 -17.02385 42.99661  1.000 25.84379 ?  104 ARG   B CZ  1 
ATOM   3093 N NH1 . ARG   B 1 124 ? -11.44591 -17.91124 42.74864  1.000 23.19964 ?  104 ARG   B NH1 1 
ATOM   3094 N NH2 . ARG   B 1 124 ? -12.74151 -16.77618 44.25674  1.000 23.17234 ?  104 ARG   B NH2 1 
ATOM   3095 N N   . VAL   B 1 125 ? -14.45260 -11.28778 38.94152  1.000 23.16605 ?  105 VAL   B N   1 
ATOM   3096 C CA  . VAL   B 1 125 ? -14.89876 -9.94859  39.31697  1.000 24.49750 ?  105 VAL   B CA  1 
ATOM   3097 C C   . VAL   B 1 125 ? -16.20560 -9.60898  38.61246  1.000 27.53894 ?  105 VAL   B C   1 
ATOM   3098 O O   . VAL   B 1 125 ? -17.09917 -8.98026  39.19379  1.000 25.80130 ?  105 VAL   B O   1 
ATOM   3099 C CB  . VAL   B 1 125 ? -13.80286 -8.91068  39.00685  1.000 23.37895 ?  105 VAL   B CB  1 
ATOM   3100 C CG1 . VAL   B 1 125 ? -14.32712 -7.49978  39.22252  1.000 24.73409 ?  105 VAL   B CG1 1 
ATOM   3101 C CG2 . VAL   B 1 125 ? -12.57719 -9.15303  39.87127  1.000 24.31363 ?  105 VAL   B CG2 1 
ATOM   3102 N N   . GLY   B 1 126 ? -16.34345 -10.02938 37.35812  1.000 23.27352 ?  106 GLY   B N   1 
ATOM   3103 C CA  . GLY   B 1 126 ? -17.50342 -9.72374  36.55185  1.000 26.47850 ?  106 GLY   B CA  1 
ATOM   3104 C C   . GLY   B 1 126 ? -18.68844 -10.64760 36.70636  1.000 28.10317 ?  106 GLY   B C   1 
ATOM   3105 O O   . GLY   B 1 126 ? -19.68666 -10.46935 36.00136  1.000 30.58650 ?  106 GLY   B O   1 
ATOM   3106 N N   . GLN   B 1 127 ? -18.61901 -11.63579 37.60116  1.000 28.98062 ?  107 GLN   B N   1 
ATOM   3107 C CA  . GLN   B 1 127 ? -19.75610 -12.51194 37.82984  1.000 28.83740 ?  107 GLN   B CA  1 
ATOM   3108 C C   . GLN   B 1 127 ? -20.91487 -11.72359 38.43789  1.000 29.52407 ?  107 GLN   B C   1 
ATOM   3109 O O   . GLN   B 1 127 ? -20.72876 -10.60268 38.91848  1.000 26.35094 ?  107 GLN   B O   1 
ATOM   3110 C CB  . GLN   B 1 127 ? -19.36680 -13.66485 38.75563  1.000 29.93971 ?  107 GLN   B CB  1 
ATOM   3111 C CG  . GLN   B 1 127 ? -18.21593 -14.51903 38.26601  1.000 32.09222 ?  107 GLN   B CG  1 
ATOM   3112 C CD  . GLN   B 1 127 ? -17.93377 -15.68445 39.19351  1.000 36.65206 ?  107 GLN   B CD  1 
ATOM   3113 O OE1 . GLN   B 1 127 ? -17.83543 -15.51585 40.40944  1.000 45.82969 ?  107 GLN   B OE1 1 
ATOM   3114 N NE2 . GLN   B 1 127 ? -17.81067 -16.87756 38.62379  1.000 44.78863 ?  107 GLN   B NE2 1 
ATOM   3115 N N   . PRO   B 1 128 ? -22.12767 -12.28129 38.40568  1.000 36.35327 ?  108 PRO   B N   1 
ATOM   3116 C CA  . PRO   B 1 128 ? -23.24157 -11.65702 39.12921  1.000 30.58100 ?  108 PRO   B CA  1 
ATOM   3117 C C   . PRO   B 1 128 ? -22.89803 -11.45196 40.59831  1.000 27.99626 ?  108 PRO   B C   1 
ATOM   3118 O O   . PRO   B 1 128 ? -22.20655 -12.26376 41.21489  1.000 30.53215 ?  108 PRO   B O   1 
ATOM   3119 C CB  . PRO   B 1 128 ? -24.38747 -12.66043 38.95748  1.000 33.13409 ?  108 PRO   B CB  1 
ATOM   3120 C CG  . PRO   B 1 128 ? -24.06713 -13.40232 37.71486  1.000 32.27898 ?  108 PRO   B CG  1 
ATOM   3121 C CD  . PRO   B 1 128 ? -22.57676 -13.37480 37.52354  1.000 32.01643 ?  108 PRO   B CD  1 
ATOM   3122 N N   . ALA   B 1 129 ? -23.38416 -10.34643 41.15416  1.000 28.01358 ?  109 ALA   B N   1 
ATOM   3123 C CA  . ALA   B 1 129 ? -23.13399 -9.98211  42.54064  1.000 30.76030 ?  109 ALA   B CA  1 
ATOM   3124 C C   . ALA   B 1 129 ? -24.45740 -9.79937  43.26731  1.000 29.72516 ?  109 ALA   B C   1 
ATOM   3125 O O   . ALA   B 1 129 ? -25.42261 -9.28038  42.69772  1.000 31.39338 ?  109 ALA   B O   1 
ATOM   3126 C CB  . ALA   B 1 129 ? -22.30436 -8.69772  42.63782  1.000 29.06718 ?  109 ALA   B CB  1 
ATOM   3127 N N   . GLU   B 1 130 ? -24.49860 -10.22853 44.52907  1.000 32.54721 ?  110 GLU   B N   1 
ATOM   3128 C CA  . GLU   B 1 130 ? -25.72073 -10.11963 45.31412  1.000 39.07913 ?  110 GLU   B CA  1 
ATOM   3129 C C   . GLU   B 1 130 ? -25.98710 -8.70140  45.79980  1.000 34.68236 ?  110 GLU   B C   1 
ATOM   3130 O O   . GLU   B 1 130 ? -27.13414 -8.38249  46.13109  1.000 39.47981 ?  110 GLU   B O   1 
ATOM   3131 C CB  . GLU   B 1 130 ? -25.66477 -11.06987 46.51272  1.000 40.29394 ?  110 GLU   B CB  1 
ATOM   3132 N N   . SER   B 1 131 ? -24.96830 -7.84660  45.84506  1.000 30.14705 ?  111 SER   B N   1 
ATOM   3133 C CA  . SER   B 1 131 ? -25.13662 -6.49290  46.35562  1.000 26.84496 ?  111 SER   B CA  1 
ATOM   3134 C C   . SER   B 1 131 ? -24.01114 -5.61777  45.82375  1.000 28.71011 ?  111 SER   B C   1 
ATOM   3135 O O   . SER   B 1 131 ? -23.05422 -6.09992  45.21327  1.000 28.97345 ?  111 SER   B O   1 
ATOM   3136 C CB  . SER   B 1 131 ? -25.15837 -6.47460  47.88673  1.000 28.46886 ?  111 SER   B CB  1 
ATOM   3137 O OG  . SER   B 1 131 ? -23.87879 -6.78591  48.41060  1.000 33.00799 ?  111 SER   B OG  1 
ATOM   3138 N N   . ARG   B 1 132 ? -24.14192 -4.31219  46.07154  1.000 28.86609 ?  112 ARG   B N   1 
ATOM   3139 C CA  . ARG   B 1 132 ? -23.09404 -3.37301  45.68504  1.000 26.34201 ?  112 ARG   B CA  1 
ATOM   3140 C C   . ARG   B 1 132 ? -21.83470 -3.57998  46.51710  1.000 31.80516 ?  112 ARG   B C   1 
ATOM   3141 O O   . ARG   B 1 132 ? -20.71571 -3.42991  46.01093  1.000 28.08417 ?  112 ARG   B O   1 
ATOM   3142 C CB  . ARG   B 1 132 ? -23.60332 -1.93852  45.82804  1.000 26.11551 ?  112 ARG   B CB  1 
ATOM   3143 C CG  . ARG   B 1 132 ? -22.57312 -0.86767  45.50970  1.000 24.10071 ?  112 ARG   B CG  1 
ATOM   3144 C CD  . ARG   B 1 132 ? -23.18808 0.51872   45.59321  1.000 28.87439 ?  112 ARG   B CD  1 
ATOM   3145 N NE  . ARG   B 1 132 ? -24.31716 0.66958   44.68321  1.000 35.50222 ?  112 ARG   B NE  1 
ATOM   3146 C CZ  . ARG   B 1 132 ? -24.20499 0.95715   43.39369  1.000 30.00680 ?  112 ARG   B CZ  1 
ATOM   3147 N NH1 . ARG   B 1 132 ? -23.02385 1.14134   42.82703  1.000 33.20252 ?  112 ARG   B NH1 1 
ATOM   3148 N NH2 . ARG   B 1 132 ? -25.30543 1.06759   42.65509  1.000 31.17743 ?  112 ARG   B NH2 1 
ATOM   3149 N N   . ALA   B 1 133 ? -21.99836 -3.93045  47.79533  1.000 25.81509 ?  113 ALA   B N   1 
ATOM   3150 C CA  . ALA   B 1 133 ? -20.84557 -4.12268  48.66795  1.000 34.01937 ?  113 ALA   B CA  1 
ATOM   3151 C C   . ALA   B 1 133 ? -20.00829 -5.32222  48.24531  1.000 23.87966 ?  113 ALA   B C   1 
ATOM   3152 O O   . ALA   B 1 133 ? -18.77954 -5.29368  48.37875  1.000 29.38336 ?  113 ALA   B O   1 
ATOM   3153 C CB  . ALA   B 1 133 ? -21.30431 -4.27961  50.11753  1.000 30.96874 ?  113 ALA   B CB  1 
ATOM   3154 N N   . GLU   B 1 134 ? -20.64544 -6.38103  47.73932  1.000 30.80496 ?  114 GLU   B N   1 
ATOM   3155 C CA  . GLU   B 1 134 ? -19.88415 -7.53794  47.27973  1.000 28.84513 ?  114 GLU   B CA  1 
ATOM   3156 C C   . GLU   B 1 134 ? -19.09328 -7.21021  46.01935  1.000 32.59885 ?  114 GLU   B C   1 
ATOM   3157 O O   . GLU   B 1 134 ? -17.94683 -7.64776  45.86916  1.000 30.47015 ?  114 GLU   B O   1 
ATOM   3158 C CB  . GLU   B 1 134 ? -20.81482 -8.72683  47.03796  1.000 31.26863 ?  114 GLU   B CB  1 
ATOM   3159 C CG  . GLU   B 1 134 ? -20.09450 -9.97834  46.55225  1.000 31.98287 ?  114 GLU   B CG  1 
ATOM   3160 C CD  . GLU   B 1 134 ? -21.02325 -11.16402 46.37926  1.000 44.40985 ?  114 GLU   B CD  1 
ATOM   3161 O OE1 . GLU   B 1 134 ? -21.97027 -11.06807 45.57021  1.000 44.32091 ?  114 GLU   B OE1 1 
ATOM   3162 O OE2 . GLU   B 1 134 ? -20.80381 -12.19386 47.05207  1.000 43.59211 ?  114 GLU   B OE2 1 
ATOM   3163 N N   . LEU   B 1 135 ? -19.68429 -6.43709  45.10500  1.000 26.91305 ?  115 LEU   B N   1 
ATOM   3164 C CA  . LEU   B 1 135 ? -18.96322 -6.04456  43.89824  1.000 24.40849 ?  115 LEU   B CA  1 
ATOM   3165 C C   . LEU   B 1 135 ? -17.81898 -5.09265  44.22459  1.000 20.91678 ?  115 LEU   B C   1 
ATOM   3166 O O   . LEU   B 1 135 ? -16.72872 -5.20330  43.65117  1.000 24.45944 ?  115 LEU   B O   1 
ATOM   3167 C CB  . LEU   B 1 135 ? -19.92352 -5.40649  42.89484  1.000 23.49163 ?  115 LEU   B CB  1 
ATOM   3168 C CG  . LEU   B 1 135 ? -19.26959 -4.74228  41.68187  1.000 24.86719 ?  115 LEU   B CG  1 
ATOM   3169 C CD1 . LEU   B 1 135 ? -18.60470 -5.78266  40.79489  1.000 26.63449 ?  115 LEU   B CD1 1 
ATOM   3170 C CD2 . LEU   B 1 135 ? -20.29114 -3.93859  40.89720  1.000 32.30220 ?  115 LEU   B CD2 1 
ATOM   3171 N N   . LEU   B 1 136 ? -18.04884 -4.15210  45.14412  1.000 20.63434 ?  116 LEU   B N   1 
ATOM   3172 C CA  . LEU   B 1 136 ? -16.99068 -3.23083  45.54602  1.000 21.46314 ?  116 LEU   B CA  1 
ATOM   3173 C C   . LEU   B 1 136 ? -15.84084 -3.96838  46.21916  1.000 27.22061 ?  116 LEU   B C   1 
ATOM   3174 O O   . LEU   B 1 136 ? -14.67054 -3.61797  46.02560  1.000 22.44715 ?  116 LEU   B O   1 
ATOM   3175 C CB  . LEU   B 1 136 ? -17.55712 -2.15679  46.47433  1.000 17.57292 ?  116 LEU   B CB  1 
ATOM   3176 C CG  . LEU   B 1 136 ? -16.57893 -1.08208  46.95200  1.000 27.26443 ?  116 LEU   B CG  1 
ATOM   3177 C CD1 . LEU   B 1 136 ? -16.07465 -0.24224  45.78899  1.000 28.47182 ?  116 LEU   B CD1 1 
ATOM   3178 C CD2 . LEU   B 1 136 ? -17.23495 -0.20154  48.00318  1.000 25.96186 ?  116 LEU   B CD2 1 
ATOM   3179 N N   . ASP   B 1 137 ? -16.15360 -4.99394  47.01462  1.000 25.85086 ?  117 ASP   B N   1 
ATOM   3180 C CA  . ASP   B 1 137 ? -15.10098 -5.76708  47.66478  1.000 27.39398 ?  117 ASP   B CA  1 
ATOM   3181 C C   . ASP   B 1 137 ? -14.26751 -6.52755  46.64021  1.000 23.93464 ?  117 ASP   B C   1 
ATOM   3182 O O   . ASP   B 1 137 ? -13.03980 -6.60862  46.76625  1.000 23.00234 ?  117 ASP   B O   1 
ATOM   3183 C CB  . ASP   B 1 137 ? -15.70956 -6.72459  48.68989  1.000 31.71139 ?  117 ASP   B CB  1 
ATOM   3184 C CG  . ASP   B 1 137 ? -14.67506 -7.62892  49.32983  1.000 33.79003 ?  117 ASP   B CG  1 
ATOM   3185 O OD1 . ASP   B 1 137 ? -13.53104 -7.17332  49.53731  1.000 32.06932 ?  117 ASP   B OD1 1 
ATOM   3186 O OD2 . ASP   B 1 137 ? -15.00585 -8.79530  49.62820  1.000 37.25459 ?  117 ASP   B OD2 1 
ATOM   3187 N N   . ARG   B 1 138 ? -14.91566 -7.08885  45.61571  1.000 24.30607 ?  118 ARG   B N   1 
ATOM   3188 C CA  . ARG   B 1 138 ? -14.17293 -7.71481  44.52539  1.000 24.86651 ?  118 ARG   B CA  1 
ATOM   3189 C C   . ARG   B 1 138 ? -13.26744 -6.70396  43.83314  1.000 22.88164 ?  118 ARG   B C   1 
ATOM   3190 O O   . ARG   B 1 138 ? -12.07135 -6.95086  43.63930  1.000 22.79406 ?  118 ARG   B O   1 
ATOM   3191 C CB  . ARG   B 1 138 ? -15.13483 -8.33377  43.50940  1.000 27.68065 ?  118 ARG   B CB  1 
ATOM   3192 C CG  . ARG   B 1 138 ? -16.05607 -9.41845  44.03508  1.000 32.18383 ?  118 ARG   B CG  1 
ATOM   3193 C CD  . ARG   B 1 138 ? -16.40455 -10.37748 42.90898  1.000 34.49548 ?  118 ARG   B CD  1 
ATOM   3194 N NE  . ARG   B 1 138 ? -17.66438 -11.07202 43.13738  1.000 33.53940 ?  118 ARG   B NE  1 
ATOM   3195 C CZ  . ARG   B 1 138 ? -18.72026 -10.98011 42.34142  1.000 36.90551 ?  118 ARG   B CZ  1 
ATOM   3196 N NH1 . ARG   B 1 138 ? -18.70687 -10.21493 41.26230  1.000 38.04476 ?  118 ARG   B NH1 1 
ATOM   3197 N NH2 . ARG   B 1 138 ? -19.81910 -11.66749 42.63929  1.000 33.62663 ?  118 ARG   B NH2 1 
ATOM   3198 N N   . LEU   B 1 139 ? -13.82806 -5.55257  43.45445  1.000 22.99478 ?  119 LEU   B N   1 
ATOM   3199 C CA  . LEU   B 1 139 ? -13.06921 -4.56924  42.68868  1.000 23.93487 ?  119 LEU   B CA  1 
ATOM   3200 C C   . LEU   B 1 139 ? -11.91377 -4.00074  43.50182  1.000 23.85277 ?  119 LEU   B C   1 
ATOM   3201 O O   . LEU   B 1 139 ? -10.80124 -3.84965  42.98548  1.000 20.83186 ?  119 LEU   B O   1 
ATOM   3202 C CB  . LEU   B 1 139 ? -13.99646 -3.45047  42.21382  1.000 16.95921 ?  119 LEU   B CB  1 
ATOM   3203 C CG  . LEU   B 1 139 ? -14.87181 -3.78734  41.00402  1.000 18.06291 ?  119 LEU   B CG  1 
ATOM   3204 C CD1 . LEU   B 1 139 ? -15.98468 -2.76392  40.83461  1.000 17.23050 ?  119 LEU   B CD1 1 
ATOM   3205 C CD2 . LEU   B 1 139 ? -14.02819 -3.87928  39.74323  1.000 13.04344 ?  119 LEU   B CD2 1 
ATOM   3206 N N   . THR   B 1 140 ? -12.15562 -3.68504  44.77731  1.000 23.00559 ?  120 THR   B N   1 
ATOM   3207 C CA  . THR   B 1 140 ? -11.09938 -3.12355  45.61500  1.000 20.68944 ?  120 THR   B CA  1 
ATOM   3208 C C   . THR   B 1 140 ? -9.96182  -4.11826  45.81406  1.000 25.25684 ?  120 THR   B C   1 
ATOM   3209 O O   . THR   B 1 140 ? -8.78341  -3.75246  45.72276  1.000 22.65408 ?  120 THR   B O   1 
ATOM   3210 C CB  . THR   B 1 140 ? -11.67556 -2.68831  46.96349  1.000 24.99123 ?  120 THR   B CB  1 
ATOM   3211 O OG1 . THR   B 1 140 ? -12.56578 -1.58182  46.76920  1.000 28.81932 ?  120 THR   B OG1 1 
ATOM   3212 C CG2 . THR   B 1 140 ? -10.56470 -2.27555  47.91517  1.000 22.65015 ?  120 THR   B CG2 1 
ATOM   3213 N N   . THR   B 1 141 ? -10.29421 -5.38315  46.07970  1.000 19.95731 ?  121 THR   B N   1 
ATOM   3214 C CA  . THR   B 1 141 ? -9.26110  -6.39771  46.26223  1.000 22.07591 ?  121 THR   B CA  1 
ATOM   3215 C C   . THR   B 1 141 ? -8.49429  -6.63792  44.96755  1.000 22.02047 ?  121 THR   B C   1 
ATOM   3216 O O   . THR   B 1 141 ? -7.25737  -6.64253  44.95827  1.000 21.95349 ?  121 THR   B O   1 
ATOM   3217 C CB  . THR   B 1 141 ? -9.88563  -7.69920  46.76735  1.000 27.88743 ?  121 THR   B CB  1 
ATOM   3218 O OG1 . THR   B 1 141 ? -10.37123 -7.51045  48.10215  1.000 26.40072 ?  121 THR   B OG1 1 
ATOM   3219 C CG2 . THR   B 1 141 ? -8.85849  -8.82476  46.76026  1.000 23.49223 ?  121 THR   B CG2 1 
ATOM   3220 N N   . PHE   B 1 142 ? -9.21584  -6.83701  43.86118  1.000 26.21240 ?  122 PHE   B N   1 
ATOM   3221 C CA  . PHE   B 1 142 ? -8.55946  -7.05631  42.57631  1.000 21.01160 ?  122 PHE   B CA  1 
ATOM   3222 C C   . PHE   B 1 142 ? -7.70683  -5.85795  42.17959  1.000 21.16297 ?  122 PHE   B C   1 
ATOM   3223 O O   . PHE   B 1 142 ? -6.61555  -6.02228  41.62153  1.000 19.82144 ?  122 PHE   B O   1 
ATOM   3224 C CB  . PHE   B 1 142 ? -9.60358  -7.35386  41.50027  1.000 16.59524 ?  122 PHE   B CB  1 
ATOM   3225 C CG  . PHE   B 1 142 ? -9.02346  -7.87922  40.21795  1.000 17.47567 ?  122 PHE   B CG  1 
ATOM   3226 C CD1 . PHE   B 1 142 ? -8.09823  -8.91110  40.22812  1.000 16.12730 ?  122 PHE   B CD1 1 
ATOM   3227 C CD2 . PHE   B 1 142 ? -9.40607  -7.34092  39.00071  1.000 15.67927 ?  122 PHE   B CD2 1 
ATOM   3228 C CE1 . PHE   B 1 142 ? -7.56585  -9.39536  39.04708  1.000 13.11787 ?  122 PHE   B CE1 1 
ATOM   3229 C CE2 . PHE   B 1 142 ? -8.87798  -7.81991  37.81723  1.000 15.02006 ?  122 PHE   B CE2 1 
ATOM   3230 C CZ  . PHE   B 1 142 ? -7.95689  -8.84817  37.83980  1.000 19.21836 ?  122 PHE   B CZ  1 
ATOM   3231 N N   . THR   B 1 143 ? -8.18358  -4.64340  42.46814  1.000 19.49968 ?  123 THR   B N   1 
ATOM   3232 C CA  . THR   B 1 143 ? -7.42024  -3.44922  42.11839  1.000 21.85240 ?  123 THR   B CA  1 
ATOM   3233 C C   . THR   B 1 143 ? -6.09774  -3.39959  42.87150  1.000 18.70443 ?  123 THR   B C   1 
ATOM   3234 O O   . THR   B 1 143 ? -5.05313  -3.09905  42.28281  1.000 20.53980 ?  123 THR   B O   1 
ATOM   3235 C CB  . THR   B 1 143 ? -8.24110  -2.19012  42.40031  1.000 18.79152 ?  123 THR   B CB  1 
ATOM   3236 O OG1 . THR   B 1 143 ? -9.41547  -2.19105  41.57892  1.000 20.48041 ?  123 THR   B OG1 1 
ATOM   3237 C CG2 . THR   B 1 143 ? -7.42413  -0.94052  42.10231  1.000 18.56579 ?  123 THR   B CG2 1 
ATOM   3238 N N   . GLU   B 1 144 ? -6.11862  -3.69474  44.17422  1.000 17.25792 ?  124 GLU   B N   1 
ATOM   3239 C CA  . GLU   B 1 144 ? -4.87399  -3.70498  44.93444  1.000 16.44857 ?  124 GLU   B CA  1 
ATOM   3240 C C   . GLU   B 1 144 ? -3.93393  -4.79642  44.44155  1.000 17.91392 ?  124 GLU   B C   1 
ATOM   3241 O O   . GLU   B 1 144 ? -2.70980  -4.62460  44.47684  1.000 21.41014 ?  124 GLU   B O   1 
ATOM   3242 C CB  . GLU   B 1 144 ? -5.15857  -3.88644  46.42592  1.000 17.59583 ?  124 GLU   B CB  1 
ATOM   3243 C CG  . GLU   B 1 144 ? -3.92410  -3.72583  47.30083  1.000 19.93728 ?  124 GLU   B CG  1 
ATOM   3244 C CD  . GLU   B 1 144 ? -4.22843  -3.83784  48.77992  1.000 23.39244 ?  124 GLU   B CD  1 
ATOM   3245 O OE1 . GLU   B 1 144 ? -5.41930  -3.94615  49.13870  1.000 27.73746 ?  124 GLU   B OE1 1 
ATOM   3246 O OE2 . GLU   B 1 144 ? -3.27222  -3.82763  49.58430  1.000 26.18522 ?  124 GLU   B OE2 1 
ATOM   3247 N N   . TYR   B 1 145 ? -4.48449  -5.91971  43.97472  1.000 22.45905 ?  125 TYR   B N   1 
ATOM   3248 C CA  . TYR   B 1 145 ? -3.64972  -6.99438  43.44700  1.000 17.60180 ?  125 TYR   B CA  1 
ATOM   3249 C C   . TYR   B 1 145 ? -2.95426  -6.56519  42.16263  1.000 18.12002 ?  125 TYR   B C   1 
ATOM   3250 O O   . TYR   B 1 145 ? -1.74181  -6.75167  42.00813  1.000 18.32590 ?  125 TYR   B O   1 
ATOM   3251 C CB  . TYR   B 1 145 ? -4.49578  -8.24703  43.21767  1.000 17.68235 ?  125 TYR   B CB  1 
ATOM   3252 C CG  . TYR   B 1 145 ? -3.81188  -9.31677  42.39716  1.000 19.69918 ?  125 TYR   B CG  1 
ATOM   3253 C CD1 . TYR   B 1 145 ? -2.74205  -10.03642 42.91297  1.000 19.87644 ?  125 TYR   B CD1 1 
ATOM   3254 C CD2 . TYR   B 1 145 ? -4.24423  -9.61625  41.11177  1.000 20.04204 ?  125 TYR   B CD2 1 
ATOM   3255 C CE1 . TYR   B 1 145 ? -2.11658  -11.01874 42.16878  1.000 20.55041 ?  125 TYR   B CE1 1 
ATOM   3256 C CE2 . TYR   B 1 145 ? -3.62595  -10.59717 40.36055  1.000 21.40319 ?  125 TYR   B CE2 1 
ATOM   3257 C CZ  . TYR   B 1 145 ? -2.56318  -11.29464 40.89399  1.000 17.89197 ?  125 TYR   B CZ  1 
ATOM   3258 O OH  . TYR   B 1 145 ? -1.94585  -12.27098 40.14788  1.000 24.68687 ?  125 TYR   B OH  1 
ATOM   3259 N N   . VAL   B 1 146 ? -3.70711  -5.97918  41.23039  1.000 20.36336 ?  126 VAL   B N   1 
ATOM   3260 C CA  . VAL   B 1 146 ? -3.10132  -5.49873  39.99471  1.000 19.49203 ?  126 VAL   B CA  1 
ATOM   3261 C C   . VAL   B 1 146 ? -2.21582  -4.28880  40.26447  1.000 19.53490 ?  126 VAL   B C   1 
ATOM   3262 O O   . VAL   B 1 146 ? -1.22862  -4.06464  39.55326  1.000 22.46799 ?  126 VAL   B O   1 
ATOM   3263 C CB  . VAL   B 1 146 ? -4.19554  -5.19288  38.95588  1.000 17.71940 ?  126 VAL   B CB  1 
ATOM   3264 C CG1 . VAL   B 1 146 ? -3.57823  -4.86558  37.60621  1.000 18.61398 ?  126 VAL   B CG1 1 
ATOM   3265 C CG2 . VAL   B 1 146 ? -5.13970  -6.37642  38.83299  1.000 21.78849 ?  126 VAL   B CG2 1 
ATOM   3266 N N   . ASN   B 1 147 ? -2.53660  -3.49924  41.29420  1.000 17.09938 ?  127 ASN   B N   1 
ATOM   3267 C CA  . ASN   B 1 147 ? -1.68303  -2.36946  41.65022  1.000 16.05710 ?  127 ASN   B CA  1 
ATOM   3268 C C   . ASN   B 1 147 ? -0.28459  -2.83530  42.03369  1.000 19.17588 ?  127 ASN   B C   1 
ATOM   3269 O O   . ASN   B 1 147 ? 0.71334   -2.22550  41.63305  1.000 19.31209 ?  127 ASN   B O   1 
ATOM   3270 C CB  . ASN   B 1 147 ? -2.30998  -1.57135  42.79310  1.000 18.76384 ?  127 ASN   B CB  1 
ATOM   3271 C CG  . ASN   B 1 147 ? -3.34075  -0.57354  42.30910  1.000 20.10573 ?  127 ASN   B CG  1 
ATOM   3272 O OD1 . ASN   B 1 147 ? -3.47218  -0.33295  41.10998  1.000 24.82514 ?  127 ASN   B OD1 1 
ATOM   3273 N ND2 . ASN   B 1 147 ? -4.08079  0.01299   43.24238  1.000 16.75076 ?  127 ASN   B ND2 1 
ATOM   3274 N N   . ARG   B 1 148 ? -0.19077  -3.92008  42.80453  1.000 17.82100 ?  128 ARG   B N   1 
ATOM   3275 C CA  . ARG   B 1 148 ? 1.11785   -4.42358  43.20425  1.000 19.77638 ?  128 ARG   B CA  1 
ATOM   3276 C C   . ARG   B 1 148 ? 1.85156   -5.07206  42.03635  1.000 21.04260 ?  128 ARG   B C   1 
ATOM   3277 O O   . ARG   B 1 148 ? 3.08500   -5.00574  41.96890  1.000 21.52525 ?  128 ARG   B O   1 
ATOM   3278 C CB  . ARG   B 1 148 ? 0.96546   -5.40783  44.36256  1.000 18.85368 ?  128 ARG   B CB  1 
ATOM   3279 C CG  . ARG   B 1 148 ? 2.28094   -5.87588  44.95080  1.000 21.02503 ?  128 ARG   B CG  1 
ATOM   3280 C CD  . ARG   B 1 148 ? 3.09693   -4.71661  45.50022  1.000 20.43929 ?  128 ARG   B CD  1 
ATOM   3281 N NE  . ARG   B 1 148 ? 2.43603   -4.05367  46.61791  1.000 21.65642 ?  128 ARG   B NE  1 
ATOM   3282 C CZ  . ARG   B 1 148 ? 2.72029   -2.82691  47.03383  1.000 26.75086 ?  128 ARG   B CZ  1 
ATOM   3283 N NH1 . ARG   B 1 148 ? 3.67140   -2.10592  46.46232  1.000 21.87374 ?  128 ARG   B NH1 1 
ATOM   3284 N NH2 . ARG   B 1 148 ? 2.03750   -2.31265  48.05264  1.000 32.23182 ?  128 ARG   B NH2 1 
ATOM   3285 N N   . LEU   B 1 149 ? 1.11997   -5.70497  41.11488  1.000 17.49752 ?  129 LEU   B N   1 
ATOM   3286 C CA  . LEU   B 1 149 ? 1.74631   -6.18929  39.88877  1.000 25.83913 ?  129 LEU   B CA  1 
ATOM   3287 C C   . LEU   B 1 149 ? 2.32714   -5.03439  39.08472  1.000 21.61941 ?  129 LEU   B C   1 
ATOM   3288 O O   . LEU   B 1 149 ? 3.44875   -5.12490  38.57151  1.000 20.22700 ?  129 LEU   B O   1 
ATOM   3289 C CB  . LEU   B 1 149 ? 0.73297   -6.96846  39.04859  1.000 21.80884 ?  129 LEU   B CB  1 
ATOM   3290 C CG  . LEU   B 1 149 ? 0.25495   -8.32192  39.57936  1.000 26.61372 ?  129 LEU   B CG  1 
ATOM   3291 C CD1 . LEU   B 1 149 ? -0.75647  -8.93123  38.62073  1.000 23.26155 ?  129 LEU   B CD1 1 
ATOM   3292 C CD2 . LEU   B 1 149 ? 1.42983   -9.26220  39.79622  1.000 20.34868 ?  129 LEU   B CD2 1 
ATOM   3293 N N   . THR   B 1 150 ? 1.57703   -3.93574  38.97301  1.000 20.48159 ?  130 THR   B N   1 
ATOM   3294 C CA  . THR   B 1 150 ? 2.08470   -2.75165  38.28885  1.000 25.00749 ?  130 THR   B CA  1 
ATOM   3295 C C   . THR   B 1 150 ? 3.27733   -2.15774  39.02814  1.000 19.97048 ?  130 THR   B C   1 
ATOM   3296 O O   . THR   B 1 150 ? 4.23511   -1.68767  38.40181  1.000 18.70774 ?  130 THR   B O   1 
ATOM   3297 C CB  . THR   B 1 150 ? 0.96853   -1.71561  38.14920  1.000 21.88009 ?  130 THR   B CB  1 
ATOM   3298 O OG1 . THR   B 1 150 ? -0.06785  -2.23601  37.30596  1.000 19.39104 ?  130 THR   B OG1 1 
ATOM   3299 C CG2 . THR   B 1 150 ? 1.50470   -0.41820  37.55802  1.000 17.87406 ?  130 THR   B CG2 1 
ATOM   3300 N N   . ALA   B 1 151 ? 3.23838   -2.17880  40.36298  1.000 18.33120 ?  131 ALA   B N   1 
ATOM   3301 C CA  . ALA   B 1 151 ? 4.33890   -1.63965  41.15604  1.000 19.59217 ?  131 ALA   B CA  1 
ATOM   3302 C C   . ALA   B 1 151 ? 5.65122   -2.33809  40.82539  1.000 19.30188 ?  131 ALA   B C   1 
ATOM   3303 O O   . ALA   B 1 151 ? 6.67244   -1.68525  40.58078  1.000 17.21744 ?  131 ALA   B O   1 
ATOM   3304 C CB  . ALA   B 1 151 ? 4.02268   -1.77413  42.64575  1.000 19.13700 ?  131 ALA   B CB  1 
ATOM   3305 N N   . TRP   B 1 152 ? 5.64026   -3.67235  40.80891  1.000 19.51068 ?  132 TRP   B N   1 
ATOM   3306 C CA  . TRP   B 1 152 ? 6.86571   -4.41780  40.54231  1.000 20.78601 ?  132 TRP   B CA  1 
ATOM   3307 C C   . TRP   B 1 152 ? 7.28958   -4.28604  39.08598  1.000 22.43157 ?  132 TRP   B C   1 
ATOM   3308 O O   . TRP   B 1 152 ? 8.48698   -4.20102  38.78883  1.000 23.36708 ?  132 TRP   B O   1 
ATOM   3309 C CB  . TRP   B 1 152 ? 6.67445   -5.88535  40.91618  1.000 22.26867 ?  132 TRP   B CB  1 
ATOM   3310 C CG  . TRP   B 1 152 ? 6.74347   -6.12988  42.38638  1.000 23.03479 ?  132 TRP   B CG  1 
ATOM   3311 C CD1 . TRP   B 1 152 ? 5.69419   -6.20044  43.25467  1.000 18.26230 ?  132 TRP   B CD1 1 
ATOM   3312 C CD2 . TRP   B 1 152 ? 7.92572   -6.34783  43.16547  1.000 25.31901 ?  132 TRP   B CD2 1 
ATOM   3313 N NE1 . TRP   B 1 152 ? 6.14947   -6.44478  44.52780  1.000 25.09021 ?  132 TRP   B NE1 1 
ATOM   3314 C CE2 . TRP   B 1 152 ? 7.51615   -6.53947  44.49987  1.000 27.38297 ?  132 TRP   B CE2 1 
ATOM   3315 C CE3 . TRP   B 1 152 ? 9.29066   -6.39685  42.86476  1.000 31.39910 ?  132 TRP   B CE3 1 
ATOM   3316 C CZ2 . TRP   B 1 152 ? 8.42173   -6.77613  45.53218  1.000 32.05287 ?  132 TRP   B CZ2 1 
ATOM   3317 C CZ3 . TRP   B 1 152 ? 10.18855  -6.63229  43.89155  1.000 30.14848 ?  132 TRP   B CZ3 1 
ATOM   3318 C CH2 . TRP   B 1 152 ? 9.74994   -6.81902  45.20859  1.000 27.69831 ?  132 TRP   B CH2 1 
ATOM   3319 N N   . SER   B 1 153 ? 6.32277   -4.27097  38.16453  1.000 17.72389 ?  133 SER   B N   1 
ATOM   3320 C CA  . SER   B 1 153 ? 6.64836   -4.09382  36.75291  1.000 20.93967 ?  133 SER   B CA  1 
ATOM   3321 C C   . SER   B 1 153 ? 7.29455   -2.73717  36.50299  1.000 17.88156 ?  133 SER   B C   1 
ATOM   3322 O O   . SER   B 1 153 ? 8.21088   -2.61891  35.68046  1.000 23.77927 ?  133 SER   B O   1 
ATOM   3323 C CB  . SER   B 1 153 ? 5.38978   -4.25420  35.89975  1.000 17.99670 ?  133 SER   B CB  1 
ATOM   3324 O OG  . SER   B 1 153 ? 5.71104   -4.27600  34.51961  1.000 20.86897 ?  133 SER   B OG  1 
ATOM   3325 N N   . HIS   B 1 154 ? 6.82898   -1.70039  37.20381  1.000 21.47499 ?  134 HIS   B N   1 
ATOM   3326 C CA  . HIS   B 1 154 ? 7.43025   -0.37896  37.05657  1.000 22.37638 ?  134 HIS   B CA  1 
ATOM   3327 C C   . HIS   B 1 154 ? 8.86306   -0.36123  37.57363  1.000 20.86837 ?  134 HIS   B C   1 
ATOM   3328 O O   . HIS   B 1 154 ? 9.74208   0.26621   36.97006  1.000 20.70554 ?  134 HIS   B O   1 
ATOM   3329 C CB  . HIS   B 1 154 ? 6.58763   0.66484   37.78737  1.000 20.93743 ?  134 HIS   B CB  1 
ATOM   3330 C CG  . HIS   B 1 154 ? 7.20700   2.02689   37.81298  1.000 24.96993 ?  134 HIS   B CG  1 
ATOM   3331 N ND1 . HIS   B 1 154 ? 7.15977   2.88752   36.73754  1.000 28.28254 ?  134 HIS   B ND1 1 
ATOM   3332 C CD2 . HIS   B 1 154 ? 7.89556   2.67406   38.78287  1.000 28.81454 ?  134 HIS   B CD2 1 
ATOM   3333 C CE1 . HIS   B 1 154 ? 7.78864   4.00789   37.04532  1.000 27.82150 ?  134 HIS   B CE1 1 
ATOM   3334 N NE2 . HIS   B 1 154 ? 8.24434   3.90410   38.28077  1.000 26.11420 ?  134 HIS   B NE2 1 
ATOM   3335 N N   . HIS   B 1 155 ? 9.11600   -1.04285  38.69299  1.000 21.42967 ?  135 HIS   B N   1 
ATOM   3336 C CA  . HIS   B 1 155 ? 10.45654  -1.05190  39.26876  1.000 25.84375 ?  135 HIS   B CA  1 
ATOM   3337 C C   . HIS   B 1 155 ? 11.46425  -1.70662  38.33231  1.000 21.17474 ?  135 HIS   B C   1 
ATOM   3338 O O   . HIS   B 1 155 ? 12.62203  -1.27846  38.25742  1.000 24.61074 ?  135 HIS   B O   1 
ATOM   3339 C CB  . HIS   B 1 155 ? 10.44387  -1.77284  40.61589  1.000 21.78397 ?  135 HIS   B CB  1 
ATOM   3340 C CG  . HIS   B 1 155 ? 11.80782  -2.12498  41.12031  1.000 27.34538 ?  135 HIS   B CG  1 
ATOM   3341 N ND1 . HIS   B 1 155 ? 12.66204  -1.19293  41.66891  1.000 24.34123 ?  135 HIS   B ND1 1 
ATOM   3342 C CD2 . HIS   B 1 155 ? 12.47220  -3.30462  41.14440  1.000 30.30924 ?  135 HIS   B CD2 1 
ATOM   3343 C CE1 . HIS   B 1 155 ? 13.79065  -1.78471  42.01708  1.000 30.91725 ?  135 HIS   B CE1 1 
ATOM   3344 N NE2 . HIS   B 1 155 ? 13.70151  -3.06611  41.70901  1.000 32.17968 ?  135 HIS   B NE2 1 
ATOM   3345 N N   . TYR   B 1 156 ? 11.04492  -2.74194  37.60691  1.000 24.75688 ?  136 TYR   B N   1 
ATOM   3346 C CA  . TYR   B 1 156 ? 11.96886  -3.55224  36.82771  1.000 26.48491 ?  136 TYR   B CA  1 
ATOM   3347 C C   . TYR   B 1 156 ? 11.98191  -3.22136  35.34107  1.000 24.81245 ?  136 TYR   B C   1 
ATOM   3348 O O   . TYR   B 1 156 ? 12.82649  -3.75992  34.61773  1.000 24.30281 ?  136 TYR   B O   1 
ATOM   3349 C CB  . TYR   B 1 156 ? 11.64409  -5.03891  37.01262  1.000 23.38294 ?  136 TYR   B CB  1 
ATOM   3350 C CG  . TYR   B 1 156 ? 12.27866  -5.64468  38.24356  1.000 25.57044 ?  136 TYR   B CG  1 
ATOM   3351 C CD1 . TYR   B 1 156 ? 13.65883  -5.68588  38.38589  1.000 32.71444 ?  136 TYR   B CD1 1 
ATOM   3352 C CD2 . TYR   B 1 156 ? 11.49847  -6.17394  39.26366  1.000 27.91110 ?  136 TYR   B CD2 1 
ATOM   3353 C CE1 . TYR   B 1 156 ? 14.24511  -6.23637  39.50878  1.000 30.69326 ?  136 TYR   B CE1 1 
ATOM   3354 C CE2 . TYR   B 1 156 ? 12.07633  -6.72738  40.39113  1.000 28.99727 ?  136 TYR   B CE2 1 
ATOM   3355 C CZ  . TYR   B 1 156 ? 13.45037  -6.75587  40.50769  1.000 29.29194 ?  136 TYR   B CZ  1 
ATOM   3356 O OH  . TYR   B 1 156 ? 14.03186  -7.30575  41.62760  1.000 34.12987 ?  136 TYR   B OH  1 
ATOM   3357 N N   . PHE   B 1 157 ? 11.08405  -2.36422  34.86450  1.000 26.99245 ?  137 PHE   B N   1 
ATOM   3358 C CA  . PHE   B 1 157 ? 11.09250  -2.02166  33.44994  1.000 23.13437 ?  137 PHE   B CA  1 
ATOM   3359 C C   . PHE   B 1 157 ? 12.34865  -1.22012  33.11322  1.000 22.44028 ?  137 PHE   B C   1 
ATOM   3360 O O   . PHE   B 1 157 ? 12.73083  -0.31783  33.86507  1.000 23.01356 ?  137 PHE   B O   1 
ATOM   3361 C CB  . PHE   B 1 157 ? 9.84688   -1.22291  33.06885  1.000 28.00157 ?  137 PHE   B CB  1 
ATOM   3362 C CG  . PHE   B 1 157 ? 9.58856   -1.18576  31.58905  1.000 21.58656 ?  137 PHE   B CG  1 
ATOM   3363 C CD1 . PHE   B 1 157 ? 9.06909   -2.29146  30.93784  1.000 22.68022 ?  137 PHE   B CD1 1 
ATOM   3364 C CD2 . PHE   B 1 157 ? 9.88545   -0.05526  30.84609  1.000 23.87322 ?  137 PHE   B CD2 1 
ATOM   3365 C CE1 . PHE   B 1 157 ? 8.83701   -2.26755  29.57683  1.000 25.03487 ?  137 PHE   B CE1 1 
ATOM   3366 C CE2 . PHE   B 1 157 ? 9.65542   -0.02475  29.48246  1.000 22.91460 ?  137 PHE   B CE2 1 
ATOM   3367 C CZ  . PHE   B 1 157 ? 9.13103   -1.13270  28.84802  1.000 26.67991 ?  137 PHE   B CZ  1 
ATOM   3368 N N   . PRO   B 1 158 ? 13.01377  -1.52508  31.99378  1.000 24.23777 ?  138 PRO   B N   1 
ATOM   3369 C CA  . PRO   B 1 158 ? 14.27263  -0.83356  31.63977  1.000 25.37242 ?  138 PRO   B CA  1 
ATOM   3370 C C   . PRO   B 1 158 ? 14.03669  0.57972   31.11293  1.000 23.26760 ?  138 PRO   B C   1 
ATOM   3371 O O   . PRO   B 1 158 ? 14.01557  0.85703   29.91373  1.000 30.88404 ?  138 PRO   B O   1 
ATOM   3372 C CB  . PRO   B 1 158 ? 14.87000  -1.75353  30.57324  1.000 26.79083 ?  138 PRO   B CB  1 
ATOM   3373 C CG  . PRO   B 1 158 ? 13.68522  -2.37661  29.91989  1.000 24.93535 ?  138 PRO   B CG  1 
ATOM   3374 C CD  . PRO   B 1 158 ? 12.63550  -2.53410  30.98888  1.000 23.30205 ?  138 PRO   B CD  1 
ATOM   3375 N N   . TRP   B 1 159 ? 13.85562  1.51333   32.04860  1.000 25.63191 ?  139 TRP   B N   1 
ATOM   3376 C CA  . TRP   B 1 159 ? 13.57936  2.89496   31.67715  1.000 26.95453 ?  139 TRP   B CA  1 
ATOM   3377 C C   . TRP   B 1 159 ? 14.78921  3.58555   31.05953  1.000 34.57470 ?  139 TRP   B C   1 
ATOM   3378 O O   . TRP   B 1 159 ? 14.62209  4.60120   30.37588  1.000 33.71648 ?  139 TRP   B O   1 
ATOM   3379 C CB  . TRP   B 1 159 ? 13.09088  3.67569   32.89882  1.000 23.95815 ?  139 TRP   B CB  1 
ATOM   3380 C CG  . TRP   B 1 159 ? 11.81836  3.13139   33.48187  1.000 29.34561 ?  139 TRP   B CG  1 
ATOM   3381 C CD1 . TRP   B 1 159 ? 11.66668  2.52096   34.69323  1.000 26.45191 ?  139 TRP   B CD1 1 
ATOM   3382 C CD2 . TRP   B 1 159 ? 10.52000  3.14164   32.87301  1.000 27.23547 ?  139 TRP   B CD2 1 
ATOM   3383 N NE1 . TRP   B 1 159 ? 10.35482  2.15453   34.87813  1.000 26.72593 ?  139 TRP   B NE1 1 
ATOM   3384 C CE2 . TRP   B 1 159 ? 9.63055   2.52424   33.77547  1.000 27.25125 ?  139 TRP   B CE2 1 
ATOM   3385 C CE3 . TRP   B 1 159 ? 10.02355  3.61481   31.65418  1.000 24.85487 ?  139 TRP   B CE3 1 
ATOM   3386 C CZ2 . TRP   B 1 159 ? 8.27398   2.36740   33.49777  1.000 27.66391 ?  139 TRP   B CZ2 1 
ATOM   3387 C CZ3 . TRP   B 1 159 ? 8.67554   3.45773   31.38018  1.000 26.24822 ?  139 TRP   B CZ3 1 
ATOM   3388 C CH2 . TRP   B 1 159 ? 7.81726   2.83861   32.29777  1.000 27.67739 ?  139 TRP   B CH2 1 
ATOM   3389 N N   . ASP   B 1 160 ? 15.99550  3.05936   31.27395  1.000 28.95412 ?  140 ASP   B N   1 
ATOM   3390 C CA  . ASP   B 1 160 ? 17.20316  3.64523   30.70389  1.000 34.89839 ?  140 ASP   B CA  1 
ATOM   3391 C C   . ASP   B 1 160 ? 17.47016  3.20334   29.27210  1.000 33.38763 ?  140 ASP   B C   1 
ATOM   3392 O O   . ASP   B 1 160 ? 18.48032  3.62261   28.69629  1.000 33.81239 ?  140 ASP   B O   1 
ATOM   3393 C CB  . ASP   B 1 160 ? 18.42069  3.30467   31.57014  1.000 34.08403 ?  140 ASP   B CB  1 
ATOM   3394 C CG  . ASP   B 1 160 ? 18.68041  1.81068   31.66417  1.000 35.87611 ?  140 ASP   B CG  1 
ATOM   3395 O OD1 . ASP   B 1 160 ? 17.88841  1.01871   31.11085  1.000 41.71950 ?  140 ASP   B OD1 1 
ATOM   3396 O OD2 . ASP   B 1 160 ? 19.69322  1.42728   32.28674  1.000 45.98324 ?  140 ASP   B OD2 1 
ATOM   3397 N N   . LEU   B 1 161 ? 16.59798  2.37394   28.69291  1.000 29.65816 ?  141 LEU   B N   1 
ATOM   3398 C CA  . LEU   B 1 161 ? 16.87685  1.78653   27.38579  1.000 29.78525 ?  141 LEU   B CA  1 
ATOM   3399 C C   . LEU   B 1 161 ? 17.10649  2.85696   26.32559  1.000 30.61825 ?  141 LEU   B C   1 
ATOM   3400 O O   . LEU   B 1 161 ? 17.98769  2.71459   25.46954  1.000 26.96592 ?  141 LEU   B O   1 
ATOM   3401 C CB  . LEU   B 1 161 ? 15.73123  0.86206   26.97927  1.000 30.25543 ?  141 LEU   B CB  1 
ATOM   3402 C CG  . LEU   B 1 161 ? 16.06899  -0.19117  25.92695  1.000 32.00477 ?  141 LEU   B CG  1 
ATOM   3403 C CD1 . LEU   B 1 161 ? 17.02309  -1.21618  26.50237  1.000 37.34197 ?  141 LEU   B CD1 1 
ATOM   3404 C CD2 . LEU   B 1 161 ? 14.80414  -0.86067  25.42932  1.000 35.09585 ?  141 LEU   B CD2 1 
ATOM   3405 N N   . GLY   B 1 162 ? 16.32928  3.93443   26.36592  1.000 28.21193 ?  142 GLY   B N   1 
ATOM   3406 C CA  . GLY   B 1 162 ? 16.52421  5.02943   25.43776  1.000 26.85933 ?  142 GLY   B CA  1 
ATOM   3407 C C   . GLY   B 1 162 ? 17.26779  6.18949   26.06501  1.000 32.16871 ?  142 GLY   B C   1 
ATOM   3408 O O   . GLY   B 1 162 ? 17.17005  7.32693   25.59427  1.000 33.82420 ?  142 GLY   B O   1 
ATOM   3409 N N   . GLY   B 1 163 ? 18.02035  5.90817   27.13142  1.000 29.78661 ?  143 GLY   B N   1 
ATOM   3410 C CA  . GLY   B 1 163 ? 18.71728  6.97248   27.83581  1.000 35.60038 ?  143 GLY   B CA  1 
ATOM   3411 C C   . GLY   B 1 163 ? 19.77806  7.64835   26.98871  1.000 35.85968 ?  143 GLY   B C   1 
ATOM   3412 O O   . GLY   B 1 163 ? 19.96670  8.86394   27.06791  1.000 36.82903 ?  143 GLY   B O   1 
ATOM   3413 N N   . GLU   B 1 164 ? 20.48424  6.87347   26.16745  1.000 35.85933 ?  144 GLU   B N   1 
ATOM   3414 C CA  . GLU   B 1 164 ? 21.52940  7.42387   25.31316  1.000 35.76967 ?  144 GLU   B CA  1 
ATOM   3415 C C   . GLU   B 1 164 ? 20.99442  7.89987   23.96914  1.000 38.35511 ?  144 GLU   B C   1 
ATOM   3416 O O   . GLU   B 1 164 ? 21.38014  8.97333   23.49288  1.000 31.21317 ?  144 GLU   B O   1 
ATOM   3417 C CB  . GLU   B 1 164 ? 22.62335  6.37930   25.08063  1.000 36.91447 ?  144 GLU   B CB  1 
ATOM   3418 C CG  . GLU   B 1 164 ? 23.96705  6.72876   25.68890  1.000 38.27420 ?  144 GLU   B CG  1 
ATOM   3419 C CD  . GLU   B 1 164 ? 24.99849  5.64024   25.46918  1.000 42.25359 ?  144 GLU   B CD  1 
ATOM   3420 O OE1 . GLU   B 1 164 ? 25.01054  4.66222   26.24609  1.000 45.86984 ?  144 GLU   B OE1 1 
ATOM   3421 O OE2 . GLU   B 1 164 ? 25.79373  5.76066   24.51352  1.000 40.13514 ?  144 GLU   B OE2 1 
ATOM   3422 N N   . ARG   B 1 165 ? 20.10647  7.11803   23.35204  1.000 33.19525 ?  145 ARG   B N   1 
ATOM   3423 C CA  . ARG   B 1 165 ? 19.68986  7.39672   21.98230  1.000 31.98463 ?  145 ARG   B CA  1 
ATOM   3424 C C   . ARG   B 1 165 ? 18.76886  8.60785   21.89513  1.000 29.36106 ?  145 ARG   B C   1 
ATOM   3425 O O   . ARG   B 1 165 ? 18.76260  9.30497   20.87396  1.000 28.62694 ?  145 ARG   B O   1 
ATOM   3426 C CB  . ARG   B 1 165 ? 19.00671  6.16151   21.39181  1.000 32.71164 ?  145 ARG   B CB  1 
ATOM   3427 C CG  . ARG   B 1 165 ? 18.51823  6.32304   19.96092  1.000 36.64206 ?  145 ARG   B CG  1 
ATOM   3428 C CD  . ARG   B 1 165 ? 18.10713  4.98529   19.36752  1.000 38.68328 ?  145 ARG   B CD  1 
ATOM   3429 N NE  . ARG   B 1 165 ? 19.21097  4.33545   18.67118  1.000 49.62625 ?  145 ARG   B NE  1 
ATOM   3430 C CZ  . ARG   B 1 165 ? 19.11533  3.17876   18.02991  1.000 52.90014 ?  145 ARG   B CZ  1 
ATOM   3431 N NH1 . ARG   B 1 165 ? 17.97493  2.50991   17.97679  1.000 48.46418 ?  145 ARG   B NH1 1 
ATOM   3432 N NH2 . ARG   B 1 165 ? 20.19129  2.67982   17.42788  1.000 53.40796 ?  145 ARG   B NH2 1 
ATOM   3433 N N   . TYR   B 1 166 ? 17.99679  8.88611   22.94665  1.000 29.06623 ?  146 TYR   B N   1 
ATOM   3434 C CA  . TYR   B 1 166 ? 16.95084  9.90644   22.90292  1.000 32.35179 ?  146 TYR   B CA  1 
ATOM   3435 C C   . TYR   B 1 166 ? 17.16383  10.89860  24.04970  1.000 33.97673 ?  146 TYR   B C   1 
ATOM   3436 O O   . TYR   B 1 166 ? 16.40642  10.93273  25.02119  1.000 30.10499 ?  146 TYR   B O   1 
ATOM   3437 C CB  . TYR   B 1 166 ? 15.56831  9.25875   22.95549  1.000 29.54832 ?  146 TYR   B CB  1 
ATOM   3438 C CG  . TYR   B 1 166 ? 15.33680  8.29285   21.81632  1.000 32.02241 ?  146 TYR   B CG  1 
ATOM   3439 C CD1 . TYR   B 1 166 ? 15.36109  8.72869   20.49760  1.000 28.39788 ?  146 TYR   B CD1 1 
ATOM   3440 C CD2 . TYR   B 1 166 ? 15.12250  6.94206   22.05614  1.000 32.18522 ?  146 TYR   B CD2 1 
ATOM   3441 C CE1 . TYR   B 1 166 ? 15.16032  7.85064   19.45058  1.000 32.57125 ?  146 TYR   B CE1 1 
ATOM   3442 C CE2 . TYR   B 1 166 ? 14.92198  6.05538   21.01490  1.000 28.36918 ?  146 TYR   B CE2 1 
ATOM   3443 C CZ  . TYR   B 1 166 ? 14.94171  6.51546   19.71472  1.000 32.05397 ?  146 TYR   B CZ  1 
ATOM   3444 O OH  . TYR   B 1 166 ? 14.74245  5.63852   18.67404  1.000 31.03337 ?  146 TYR   B OH  1 
ATOM   3445 N N   . ARG   B 1 167 ? 18.20305  11.71678  23.92077  1.000 39.57716 ?  147 ARG   B N   1 
ATOM   3446 C CA  . ARG   B 1 167 ? 18.51128  12.76102  24.88474  1.000 35.25029 ?  147 ARG   B CA  1 
ATOM   3447 C C   . ARG   B 1 167 ? 18.08009  14.12015  24.34927  1.000 40.63315 ?  147 ARG   B C   1 
ATOM   3448 O O   . ARG   B 1 167 ? 18.08647  14.36304  23.13987  1.000 41.54480 ?  147 ARG   B O   1 
ATOM   3449 C CB  . ARG   B 1 167 ? 20.00782  12.78790  25.20430  1.000 38.63941 ?  147 ARG   B CB  1 
ATOM   3450 C CG  . ARG   B 1 167 ? 20.41438  11.91428  26.37492  1.000 41.55545 ?  147 ARG   B CG  1 
ATOM   3451 C CD  . ARG   B 1 167 ? 21.63993  12.47286  27.07861  1.000 40.21598 ?  147 ARG   B CD  1 
ATOM   3452 N NE  . ARG   B 1 167 ? 21.27919  13.36555  28.17329  1.000 45.43864 ?  147 ARG   B NE  1 
ATOM   3453 C CZ  . ARG   B 1 167 ? 21.45939  13.08636  29.45688  1.000 51.31152 ?  147 ARG   B CZ  1 
ATOM   3454 N NH1 . ARG   B 1 167 ? 21.99349  11.94042  29.84645  1.000 52.79057 ?  147 ARG   B NH1 1 
ATOM   3455 N NH2 . ARG   B 1 167 ? 21.09356  13.97880  30.37267  1.000 52.95518 ?  147 ARG   B NH2 1 
ATOM   3456 N N   . TYR   B 1 168 ? 17.70354  15.00691  25.26573  1.000 41.62118 ?  148 TYR   B N   1 
ATOM   3457 C CA  . TYR   B 1 168 ? 17.38878  16.37594  24.89632  1.000 43.32237 ?  148 TYR   B CA  1 
ATOM   3458 C C   . TYR   B 1 168 ? 18.67170  17.15307  24.60617  1.000 52.34201 ?  148 TYR   B C   1 
ATOM   3459 O O   . TYR   B 1 168 ? 19.78778  16.65068  24.76523  1.000 53.44523 ?  148 TYR   B O   1 
ATOM   3460 C CB  . TYR   B 1 168 ? 16.58777  17.06336  26.00184  1.000 39.59491 ?  148 TYR   B CB  1 
ATOM   3461 C CG  . TYR   B 1 168 ? 15.12838  16.66791  26.05328  1.000 39.75973 ?  148 TYR   B CG  1 
ATOM   3462 C CD1 . TYR   B 1 168 ? 14.29995  16.85028  24.95373  1.000 38.31466 ?  148 TYR   B CD1 1 
ATOM   3463 C CD2 . TYR   B 1 168 ? 14.57624  16.12373  27.20601  1.000 36.23475 ?  148 TYR   B CD2 1 
ATOM   3464 C CE1 . TYR   B 1 168 ? 12.96540  16.49438  24.99807  1.000 34.54927 ?  148 TYR   B CE1 1 
ATOM   3465 C CE2 . TYR   B 1 168 ? 13.24172  15.76544  27.25928  1.000 40.33599 ?  148 TYR   B CE2 1 
ATOM   3466 C CZ  . TYR   B 1 168 ? 12.44143  15.95445  26.15242  1.000 42.88161 ?  148 TYR   B CZ  1 
ATOM   3467 O OH  . TYR   B 1 168 ? 11.11257  15.59976  26.19840  1.000 45.61285 ?  148 TYR   B OH  1 
ATOM   3468 N N   . ALA   B 1 169 ? 18.50116  18.39905  24.17516  1.000 52.32835 ?  149 ALA   B N   1 
ATOM   3469 C CA  . ALA   B 1 169 ? 19.63545  19.26507  23.86981  1.000 44.99669 ?  149 ALA   B CA  1 
ATOM   3470 C C   . ALA   B 1 169 ? 20.43144  19.59396  25.12926  1.000 43.75220 ?  149 ALA   B C   1 
ATOM   3471 O O   . ALA   B 1 169 ? 19.91202  19.51416  26.24256  1.000 40.27075 ?  149 ALA   B O   1 
ATOM   3472 C CB  . ALA   B 1 169 ? 19.16106  20.54270  23.19493  1.000 53.31945 ?  149 ALA   B CB  1 
ATOM   3473 N N   . GLN   B 1 198 ? -5.77465  18.30887  62.62152  1.000 52.07147 ?  178 GLN   B N   1 
ATOM   3474 C CA  . GLN   B 1 198 ? -4.50671  18.48345  63.31971  1.000 55.48243 ?  178 GLN   B CA  1 
ATOM   3475 C C   . GLN   B 1 198 ? -3.36274  17.79876  62.57064  1.000 51.21347 ?  178 GLN   B C   1 
ATOM   3476 O O   . GLN   B 1 198 ? -3.54524  17.30257  61.45743  1.000 44.85250 ?  178 GLN   B O   1 
ATOM   3477 C CB  . GLN   B 1 198 ? -4.61198  17.95320  64.74948  1.000 60.30411 ?  178 GLN   B CB  1 
ATOM   3478 C CG  . GLN   B 1 198 ? -5.07950  16.51140  64.85276  1.000 59.53935 ?  178 GLN   B CG  1 
ATOM   3479 C CD  . GLN   B 1 198 ? -4.91238  15.94469  66.24698  1.000 65.77814 ?  178 GLN   B CD  1 
ATOM   3480 O OE1 . GLN   B 1 198 ? -4.65565  14.75294  66.42094  1.000 71.04606 ?  178 GLN   B OE1 1 
ATOM   3481 N NE2 . GLN   B 1 198 ? -5.05286  16.80118  67.25179  1.000 66.48919 ?  178 GLN   B NE2 1 
ATOM   3482 N N   . ARG   B 1 199 ? -2.18422  17.77374  63.18555  1.000 46.77742 ?  179 ARG   B N   1 
ATOM   3483 C CA  . ARG   B 1 199 ? -0.96401  17.30066  62.54433  1.000 51.11509 ?  179 ARG   B CA  1 
ATOM   3484 C C   . ARG   B 1 199 ? -0.56658  15.95705  63.14081  1.000 49.59186 ?  179 ARG   B C   1 
ATOM   3485 O O   . ARG   B 1 199 ? -0.27150  15.86843  64.33828  1.000 46.99381 ?  179 ARG   B O   1 
ATOM   3486 C CB  . ARG   B 1 199 ? 0.15686   18.32554  62.70938  1.000 52.21152 ?  179 ARG   B CB  1 
ATOM   3487 C CG  . ARG   B 1 199 ? -0.18984  19.66951  62.09981  1.000 48.32192 ?  179 ARG   B CG  1 
ATOM   3488 C CD  . ARG   B 1 199 ? -0.29606  19.53192  60.59495  1.000 47.63008 ?  179 ARG   B CD  1 
ATOM   3489 N NE  . ARG   B 1 199 ? -0.53749  20.79678  59.91058  1.000 56.47164 ?  179 ARG   B NE  1 
ATOM   3490 C CZ  . ARG   B 1 199 ? -1.65350  21.09662  59.25872  1.000 49.54891 ?  179 ARG   B CZ  1 
ATOM   3491 N NH1 . ARG   B 1 199 ? -2.67191  20.25286  59.20438  1.000 47.64256 ?  179 ARG   B NH1 1 
ATOM   3492 N NH2 . ARG   B 1 199 ? -1.74430  22.26634  58.63286  1.000 52.41870 ?  179 ARG   B NH2 1 
ATOM   3493 N N   . ILE   B 1 200 ? -0.55116  14.92596  62.30574  1.000 42.86848 ?  180 ILE   B N   1 
ATOM   3494 C CA  . ILE   B 1 200 ? -0.27890  13.55353  62.73380  1.000 44.91869 ?  180 ILE   B CA  1 
ATOM   3495 C C   . ILE   B 1 200 ? 1.17710   13.24749  62.44957  1.000 42.52372 ?  180 ILE   B C   1 
ATOM   3496 O O   . ILE   B 1 200 ? 1.57987   13.22680  61.27304  1.000 40.77930 ?  180 ILE   B O   1 
ATOM   3497 C CB  . ILE   B 1 200 ? -1.20011  12.54720  62.02366  1.000 45.72991 ?  180 ILE   B CB  1 
ATOM   3498 C CG1 . ILE   B 1 200 ? -2.67912  12.78608  62.35208  1.000 44.77836 ?  180 ILE   B CG1 1 
ATOM   3499 C CG2 . ILE   B 1 200 ? -0.82613  11.13762  62.41260  1.000 44.05986 ?  180 ILE   B CG2 1 
ATOM   3500 C CD1 . ILE   B 1 200 ? -2.94788  13.41755  63.70542  1.000 52.93363 ?  180 ILE   B CD1 1 
ATOM   3501 N N   . PRO   B 1 201 ? 2.01019   12.98434  63.46252  1.000 39.10253 ?  181 PRO   B N   1 
ATOM   3502 C CA  . PRO   B 1 201 ? 3.43684   12.74297  63.21823  1.000 43.18335 ?  181 PRO   B CA  1 
ATOM   3503 C C   . PRO   B 1 201 ? 3.68536   11.30953  62.76513  1.000 43.48470 ?  181 PRO   B C   1 
ATOM   3504 O O   . PRO   B 1 201 ? 3.16966   10.35828  63.35707  1.000 37.76945 ?  181 PRO   B O   1 
ATOM   3505 C CB  . PRO   B 1 201 ? 4.08964   13.02025  64.57776  1.000 36.53934 ?  181 PRO   B CB  1 
ATOM   3506 C CG  . PRO   B 1 201 ? 2.98588   12.86865  65.59195  1.000 46.73131 ?  181 PRO   B CG  1 
ATOM   3507 C CD  . PRO   B 1 201 ? 1.65282   12.84619  64.88672  1.000 40.75839 ?  181 PRO   B CD  1 
ATOM   3508 N N   . VAL   B 1 202 ? 4.48440   11.16161  61.70680  1.000 36.86300 ?  182 VAL   B N   1 
ATOM   3509 C CA  . VAL   B 1 202 ? 4.84489   9.86112   61.15457  1.000 39.89246 ?  182 VAL   B CA  1 
ATOM   3510 C C   . VAL   B 1 202 ? 6.33384   9.86655   60.82753  1.000 35.51574 ?  182 VAL   B C   1 
ATOM   3511 O O   . VAL   B 1 202 ? 6.98785   10.91120  60.81295  1.000 35.40145 ?  182 VAL   B O   1 
ATOM   3512 C CB  . VAL   B 1 202 ? 4.01739   9.50731   59.90033  1.000 37.67552 ?  182 VAL   B CB  1 
ATOM   3513 C CG1 . VAL   B 1 202 ? 2.58259   9.17839   60.28389  1.000 30.46475 ?  182 VAL   B CG1 1 
ATOM   3514 C CG2 . VAL   B 1 202 ? 4.05848   10.64927  58.89917  1.000 33.73495 ?  182 VAL   B CG2 1 
ATOM   3515 N N   . ARG   B 1 203 ? 6.86729   8.67517   60.56026  1.000 35.07702 ?  183 ARG   B N   1 
ATOM   3516 C CA  . ARG   B 1 203 ? 8.28143   8.49848   60.26147  1.000 37.21358 ?  183 ARG   B CA  1 
ATOM   3517 C C   . ARG   B 1 203 ? 8.44531   7.74227   58.95148  1.000 36.01025 ?  183 ARG   B C   1 
ATOM   3518 O O   . ARG   B 1 203 ? 7.71324   6.78618   58.67992  1.000 34.63150 ?  183 ARG   B O   1 
ATOM   3519 C CB  . ARG   B 1 203 ? 9.00105   7.74704   61.38899  1.000 37.81743 ?  183 ARG   B CB  1 
ATOM   3520 N N   . LEU   B 1 204 ? 9.41238   8.17493   58.14507  1.000 28.32109 ?  184 LEU   B N   1 
ATOM   3521 C CA  . LEU   B 1 204 ? 9.73052   7.54503   56.87015  1.000 28.65593 ?  184 LEU   B CA  1 
ATOM   3522 C C   . LEU   B 1 204 ? 11.18218  7.08978   56.89568  1.000 31.99080 ?  184 LEU   B C   1 
ATOM   3523 O O   . LEU   B 1 204 ? 12.08137  7.88840   57.18033  1.000 30.77860 ?  184 LEU   B O   1 
ATOM   3524 C CB  . LEU   B 1 204 ? 9.49971   8.50380   55.69475  1.000 26.07764 ?  184 LEU   B CB  1 
ATOM   3525 C CG  . LEU   B 1 204 ? 8.07226   8.82378   55.23104  1.000 34.27817 ?  184 LEU   B CG  1 
ATOM   3526 C CD1 . LEU   B 1 204 ? 7.29738   9.64151   56.25850  1.000 28.19148 ?  184 LEU   B CD1 1 
ATOM   3527 C CD2 . LEU   B 1 204 ? 8.09491   9.53961   53.88596  1.000 27.24247 ?  184 LEU   B CD2 1 
ATOM   3528 N N   . THR   B 1 205 ? 11.40910  5.81316   56.59254  1.000 28.20924 ?  185 THR   B N   1 
ATOM   3529 C CA  . THR   B 1 205 ? 12.74079  5.22364   56.63820  1.000 33.61023 ?  185 THR   B CA  1 
ATOM   3530 C C   . THR   B 1 205 ? 13.00525  4.45965   55.35040  1.000 25.70629 ?  185 THR   B C   1 
ATOM   3531 O O   . THR   B 1 205 ? 12.19224  3.62399   54.94298  1.000 29.63789 ?  185 THR   B O   1 
ATOM   3532 C CB  . THR   B 1 205 ? 12.89160  4.28875   57.84337  1.000 27.99143 ?  185 THR   B CB  1 
ATOM   3533 O OG1 . THR   B 1 205 ? 12.55383  4.99566   59.04306  1.000 30.68420 ?  185 THR   B OG1 1 
ATOM   3534 C CG2 . THR   B 1 205 ? 14.32013  3.77975   57.94629  1.000 29.23451 ?  185 THR   B CG2 1 
ATOM   3535 N N   . TRP   B 1 206 ? 14.14147  4.74430   54.71862  1.000 26.86967 ?  186 TRP   B N   1 
ATOM   3536 C CA  . TRP   B 1 206 ? 14.55737  4.08242   53.48861  1.000 28.32826 ?  186 TRP   B CA  1 
ATOM   3537 C C   . TRP   B 1 206 ? 15.73850  3.16920   53.78654  1.000 30.07979 ?  186 TRP   B C   1 
ATOM   3538 O O   . TRP   B 1 206 ? 16.77257  3.62822   54.28408  1.000 24.66710 ?  186 TRP   B O   1 
ATOM   3539 C CB  . TRP   B 1 206 ? 14.93481  5.10115   52.41306  1.000 27.12439 ?  186 TRP   B CB  1 
ATOM   3540 C CG  . TRP   B 1 206 ? 13.78381  5.92034   51.92199  1.000 28.12733 ?  186 TRP   B CG  1 
ATOM   3541 C CD1 . TRP   B 1 206 ? 12.94660  5.61973   50.88779  1.000 31.75564 ?  186 TRP   B CD1 1 
ATOM   3542 C CD2 . TRP   B 1 206 ? 13.35192  7.18719   52.43362  1.000 27.56858 ?  186 TRP   B CD2 1 
ATOM   3543 N NE1 . TRP   B 1 206 ? 12.01400  6.61692   50.72924  1.000 28.39193 ?  186 TRP   B NE1 1 
ATOM   3544 C CE2 . TRP   B 1 206 ? 12.24215  7.59119   51.66541  1.000 30.50744 ?  186 TRP   B CE2 1 
ATOM   3545 C CE3 . TRP   B 1 206 ? 13.79434  8.01735   53.46827  1.000 30.27959 ?  186 TRP   B CE3 1 
ATOM   3546 C CZ2 . TRP   B 1 206 ? 11.56677  8.78687   51.90084  1.000 27.06318 ?  186 TRP   B CZ2 1 
ATOM   3547 C CZ3 . TRP   B 1 206 ? 13.12351  9.20498   53.69896  1.000 29.39035 ?  186 TRP   B CZ3 1 
ATOM   3548 C CH2 . TRP   B 1 206 ? 12.02220  9.57873   52.91781  1.000 28.89696 ?  186 TRP   B CH2 1 
ATOM   3549 N N   . GLN   B 1 207 ? 15.58297  1.88412   53.47830  1.000 28.50387 ?  187 GLN   B N   1 
ATOM   3550 C CA  . GLN   B 1 207 ? 16.65070  0.90377   53.57523  1.000 25.40084 ?  187 GLN   B CA  1 
ATOM   3551 C C   . GLN   B 1 207 ? 17.06070  0.43257   52.18150  1.000 30.66277 ?  187 GLN   B C   1 
ATOM   3552 O O   . GLN   B 1 207 ? 16.23819  0.42495   51.26029  1.000 33.34831 ?  187 GLN   B O   1 
ATOM   3553 C CB  . GLN   B 1 207 ? 16.22034  -0.30427  54.41803  1.000 26.08915 ?  187 GLN   B CB  1 
ATOM   3554 C CG  . GLN   B 1 207 ? 15.67825  0.05109   55.79667  1.000 22.61055 ?  187 GLN   B CG  1 
ATOM   3555 C CD  . GLN   B 1 207 ? 16.74824  0.57690   56.73995  1.000 23.65965 ?  187 GLN   B CD  1 
ATOM   3556 O OE1 . GLN   B 1 207 ? 17.94017  0.54225   56.43240  1.000 27.70884 ?  187 GLN   B OE1 1 
ATOM   3557 N NE2 . GLN   B 1 207 ? 16.32311  1.06908   57.89765  1.000 20.68368 ?  187 GLN   B NE2 1 
ATOM   3558 N N   . PRO   B 1 208 ? 18.32399  0.01799   51.98616  1.000 38.62679 ?  188 PRO   B N   1 
ATOM   3559 C CA  . PRO   B 1 208 ? 19.40143  -0.11661  52.97501  1.000 30.07505 ?  188 PRO   B CA  1 
ATOM   3560 C C   . PRO   B 1 208 ? 20.13792  1.18291   53.29215  1.000 32.35935 ?  188 PRO   B C   1 
ATOM   3561 O O   . PRO   B 1 208 ? 21.14661  1.14049   53.99674  1.000 26.44247 ?  188 PRO   B O   1 
ATOM   3562 C CB  . PRO   B 1 208 ? 20.35292  -1.10539  52.30309  1.000 30.38429 ?  188 PRO   B CB  1 
ATOM   3563 C CG  . PRO   B 1 208 ? 20.19748  -0.80804  50.85425  1.000 26.65898 ?  188 PRO   B CG  1 
ATOM   3564 C CD  . PRO   B 1 208 ? 18.73966  -0.47928  50.66176  1.000 27.14446 ?  188 PRO   B CD  1 
ATOM   3565 N N   . LEU   B 1 209 ? 19.64763  2.31308   52.77599  1.000 37.11470 ?  189 LEU   B N   1 
ATOM   3566 C CA  . LEU   B 1 209 ? 20.32210  3.58618   53.01732  1.000 33.29724 ?  189 LEU   B CA  1 
ATOM   3567 C C   . LEU   B 1 209 ? 20.36648  3.92167   54.50266  1.000 33.29859 ?  189 LEU   B C   1 
ATOM   3568 O O   . LEU   B 1 209 ? 21.36669  4.45539   54.99733  1.000 34.43805 ?  189 LEU   B O   1 
ATOM   3569 C CB  . LEU   B 1 209 ? 19.62808  4.71199   52.25074  1.000 36.40400 ?  189 LEU   B CB  1 
ATOM   3570 C CG  . LEU   B 1 209 ? 19.41910  4.62106   50.74013  1.000 37.85847 ?  189 LEU   B CG  1 
ATOM   3571 C CD1 . LEU   B 1 209 ? 19.30073  6.02538   50.17712  1.000 39.07853 ?  189 LEU   B CD1 1 
ATOM   3572 C CD2 . LEU   B 1 209 ? 20.55676  3.87240   50.06668  1.000 33.28949 ?  189 LEU   B CD2 1 
ATOM   3573 N N   . GLY   B 1 210 ? 19.29375  3.61942   55.22960  1.000 26.27658 ?  190 GLY   B N   1 
ATOM   3574 C CA  . GLY   B 1 210 ? 19.18281  4.02021   56.61340  1.000 30.55194 ?  190 GLY   B CA  1 
ATOM   3575 C C   . GLY   B 1 210 ? 18.75477  5.45397   56.82751  1.000 31.71636 ?  190 GLY   B C   1 
ATOM   3576 O O   . GLY   B 1 210 ? 18.67312  5.89062   57.98301  1.000 35.93769 ?  190 GLY   B O   1 
ATOM   3577 N N   . VAL   B 1 211 ? 18.48434  6.20208   55.75518  1.000 31.71261 ?  191 VAL   B N   1 
ATOM   3578 C CA  . VAL   B 1 211 ? 18.03949  7.58229   55.89263  1.000 33.09373 ?  191 VAL   B CA  1 
ATOM   3579 C C   . VAL   B 1 211 ? 16.67110  7.60791   56.56383  1.000 33.64254 ?  191 VAL   B C   1 
ATOM   3580 O O   . VAL   B 1 211 ? 15.83629  6.71363   56.36835  1.000 34.79903 ?  191 VAL   B O   1 
ATOM   3581 C CB  . VAL   B 1 211 ? 18.00557  8.28249   54.52132  1.000 32.69318 ?  191 VAL   B CB  1 
ATOM   3582 C CG1 . VAL   B 1 211 ? 17.70573  9.76972   54.67960  1.000 36.41551 ?  191 VAL   B CG1 1 
ATOM   3583 C CG2 . VAL   B 1 211 ? 19.32018  8.06958   53.78351  1.000 33.45856 ?  191 VAL   B CG2 1 
ATOM   3584 N N   . GLN   B 1 212 ? 16.43625  8.64642   57.36263  1.000 34.96842 ?  192 GLN   B N   1 
ATOM   3585 C CA  . GLN   B 1 212 ? 15.28340  8.69325   58.25039  1.000 35.51782 ?  192 GLN   B CA  1 
ATOM   3586 C C   . GLN   B 1 212 ? 14.79059  10.12772  58.35475  1.000 34.38449 ?  192 GLN   B C   1 
ATOM   3587 O O   . GLN   B 1 212 ? 15.59410  11.04166  58.56186  1.000 32.01322 ?  192 GLN   B O   1 
ATOM   3588 C CB  . GLN   B 1 212 ? 15.66480  8.15343   59.63144  1.000 35.46002 ?  192 GLN   B CB  1 
ATOM   3589 C CG  . GLN   B 1 212 ? 14.56118  8.16512   60.66384  1.000 40.10296 ?  192 GLN   B CG  1 
ATOM   3590 C CD  . GLN   B 1 212 ? 14.91303  7.31991   61.87314  1.000 50.40307 ?  192 GLN   B CD  1 
ATOM   3591 O OE1 . GLN   B 1 212 ? 14.80540  7.77101   63.01376  1.000 44.49463 ?  192 GLN   B OE1 1 
ATOM   3592 N NE2 . GLN   B 1 212 ? 15.34475  6.08765   61.62801  1.000 46.41634 ?  192 GLN   B NE2 1 
ATOM   3593 N N   . VAL   B 1 213 ? 13.48018  10.32329  58.21161  1.000 31.37300 ?  193 VAL   B N   1 
ATOM   3594 C CA  . VAL   B 1 213 ? 12.87375  11.64750  58.30202  1.000 33.95992 ?  193 VAL   B CA  1 
ATOM   3595 C C   . VAL   B 1 213 ? 11.58097  11.55608  59.10194  1.000 39.99738 ?  193 VAL   B C   1 
ATOM   3596 O O   . VAL   B 1 213 ? 10.83263  10.57821  58.99262  1.000 35.33298 ?  193 VAL   B O   1 
ATOM   3597 C CB  . VAL   B 1 213 ? 12.60435  12.25883  56.90812  1.000 35.38533 ?  193 VAL   B CB  1 
ATOM   3598 C CG1 . VAL   B 1 213 ? 13.90427  12.48702  56.15120  1.000 29.42992 ?  193 VAL   B CG1 1 
ATOM   3599 C CG2 . VAL   B 1 213 ? 11.66738  11.37459  56.10104  1.000 30.25725 ?  193 VAL   B CG2 1 
ATOM   3600 N N   . ASP   B 1 214 ? 11.33130  12.57358  59.91988  1.000 38.27338 ?  194 ASP   B N   1 
ATOM   3601 C CA  . ASP   B 1 214 ? 10.04299  12.75417  60.56766  1.000 37.66953 ?  194 ASP   B CA  1 
ATOM   3602 C C   . ASP   B 1 214 ? 9.13685   13.57454  59.65993  1.000 38.29824 ?  194 ASP   B C   1 
ATOM   3603 O O   . ASP   B 1 214 ? 9.59648   14.44962  58.92135  1.000 40.37535 ?  194 ASP   B O   1 
ATOM   3604 C CB  . ASP   B 1 214 ? 10.20079  13.45148  61.92022  1.000 41.23251 ?  194 ASP   B CB  1 
ATOM   3605 C CG  . ASP   B 1 214 ? 10.82395  12.55404  62.97094  1.000 52.06376 ?  194 ASP   B CG  1 
ATOM   3606 O OD1 . ASP   B 1 214 ? 11.40132  13.08742  63.94152  1.000 52.89687 ?  194 ASP   B OD1 1 
ATOM   3607 O OD2 . ASP   B 1 214 ? 10.73675  11.31611  62.82734  1.000 56.27524 ?  194 ASP   B OD2 1 
ATOM   3608 N N   . ALA   B 1 215 ? 7.84082   13.28015  59.71233  1.000 35.76151 ?  195 ALA   B N   1 
ATOM   3609 C CA  . ALA   B 1 215 ? 6.89014   13.94072  58.83193  1.000 37.76693 ?  195 ALA   B CA  1 
ATOM   3610 C C   . ALA   B 1 215 ? 5.57393   14.14314  59.56583  1.000 38.70237 ?  195 ALA   B C   1 
ATOM   3611 O O   . ALA   B 1 215 ? 5.31757   13.54326  60.61300  1.000 34.54408 ?  195 ALA   B O   1 
ATOM   3612 C CB  . ALA   B 1 215 ? 6.67412   13.14311  57.54166  1.000 43.36139 ?  195 ALA   B CB  1 
ATOM   3613 N N   . GLU   B 1 216 ? 4.73835   15.00441  58.99263  1.000 40.35637 ?  196 GLU   B N   1 
ATOM   3614 C CA  . GLU   B 1 216 ? 3.41746   15.31371  59.51897  1.000 40.28424 ?  196 GLU   B CA  1 
ATOM   3615 C C   . GLU   B 1 216 ? 2.38030   15.00230  58.45254  1.000 39.61397 ?  196 GLU   B C   1 
ATOM   3616 O O   . GLU   B 1 216 ? 2.56800   15.35244  57.28394  1.000 37.41984 ?  196 GLU   B O   1 
ATOM   3617 C CB  . GLU   B 1 216 ? 3.31927   16.78405  59.93203  1.000 42.66325 ?  196 GLU   B CB  1 
ATOM   3618 C CG  . GLU   B 1 216 ? 4.32732   17.20446  60.98331  1.000 41.13520 ?  196 GLU   B CG  1 
ATOM   3619 C CD  . GLU   B 1 216 ? 3.68961   17.43294  62.33740  1.000 48.95344 ?  196 GLU   B CD  1 
ATOM   3620 O OE1 . GLU   B 1 216 ? 2.98159   16.52684  62.82561  1.000 56.53667 ?  196 GLU   B OE1 1 
ATOM   3621 O OE2 . GLU   B 1 216 ? 3.89626   18.52187  62.91273  1.000 41.81360 ?  196 GLU   B OE2 1 
ATOM   3622 N N   . ILE   B 1 217 ? 1.29662   14.34354  58.85179  1.000 35.91193 ?  197 ILE   B N   1 
ATOM   3623 C CA  . ILE   B 1 217 ? 0.17477   14.05939  57.96407  1.000 34.60637 ?  197 ILE   B CA  1 
ATOM   3624 C C   . ILE   B 1 217 ? -0.90646  15.09893  58.22175  1.000 37.52908 ?  197 ILE   B C   1 
ATOM   3625 O O   . ILE   B 1 217 ? -1.43745  15.19120  59.33522  1.000 37.47577 ?  197 ILE   B O   1 
ATOM   3626 C CB  . ILE   B 1 217 ? -0.36752  12.63693  58.17194  1.000 32.45490 ?  197 ILE   B CB  1 
ATOM   3627 C CG1 . ILE   B 1 217 ? 0.65898   11.59887  57.71526  1.000 33.73916 ?  197 ILE   B CG1 1 
ATOM   3628 C CG2 . ILE   B 1 217 ? -1.67814  12.45693  57.42172  1.000 26.30311 ?  197 ILE   B CG2 1 
ATOM   3629 C CD1 . ILE   B 1 217 ? 1.04309   11.71801  56.25605  1.000 31.23660 ?  197 ILE   B CD1 1 
ATOM   3630 N N   . TYR   B 1 218 ? -1.23398  15.88253  57.19496  1.000 39.20597 ?  198 TYR   B N   1 
ATOM   3631 C CA  . TYR   B 1 218 ? -2.25462  16.91451  57.32278  1.000 35.15881 ?  198 TYR   B CA  1 
ATOM   3632 C C   . TYR   B 1 218 ? -3.63503  16.27516  57.40121  1.000 38.09657 ?  198 TYR   B C   1 
ATOM   3633 O O   . TYR   B 1 218 ? -4.26993  16.02232  56.37249  1.000 39.93287 ?  198 TYR   B O   1 
ATOM   3634 C CB  . TYR   B 1 218 ? -2.17298  17.89647  56.15277  1.000 36.33074 ?  198 TYR   B CB  1 
ATOM   3635 C CG  . TYR   B 1 218 ? -0.89444  18.70431  56.12567  1.000 39.88853 ?  198 TYR   B CG  1 
ATOM   3636 C CD1 . TYR   B 1 218 ? -0.16014  18.91285  57.28172  1.000 48.42303 ?  198 TYR   B CD1 1 
ATOM   3637 C CD2 . TYR   B 1 218 ? -0.43171  19.27233  54.94871  1.000 43.71094 ?  198 TYR   B CD2 1 
ATOM   3638 C CE1 . TYR   B 1 218 ? 1.00546   19.65474  57.26712  1.000 47.21372 ?  198 TYR   B CE1 1 
ATOM   3639 C CE2 . TYR   B 1 218 ? 0.73198   20.01682  54.92187  1.000 48.23627 ?  198 TYR   B CE2 1 
ATOM   3640 C CZ  . TYR   B 1 218 ? 1.44648   20.20477  56.08446  1.000 47.54624 ?  198 TYR   B CZ  1 
ATOM   3641 O OH  . TYR   B 1 218 ? 2.60530   20.94560  56.06203  1.000 56.22390 ?  198 TYR   B OH  1 
ATOM   3642 N N   . ALA   B 1 219 ? -4.10786  16.01750  58.62116  1.000 37.86007 ?  199 ALA   B N   1 
ATOM   3643 C CA  . ALA   B 1 219 ? -5.31445  15.22773  58.83258  1.000 37.35638 ?  199 ALA   B CA  1 
ATOM   3644 C C   . ALA   B 1 219 ? -6.60540  16.01054  58.62712  1.000 39.45518 ?  199 ALA   B C   1 
ATOM   3645 O O   . ALA   B 1 219 ? -7.67721  15.39591  58.59045  1.000 41.70318 ?  199 ALA   B O   1 
ATOM   3646 C CB  . ALA   B 1 219 ? -5.30609  14.62963  60.24221  1.000 42.16279 ?  199 ALA   B CB  1 
ATOM   3647 N N   . ASP   B 1 220 ? -6.54136  17.33440  58.49120  1.000 38.65803 ?  200 ASP   B N   1 
ATOM   3648 C CA  . ASP   B 1 220 ? -7.73974  18.15623  58.38449  1.000 41.53984 ?  200 ASP   B CA  1 
ATOM   3649 C C   . ASP   B 1 220 ? -7.96906  18.71640  56.98789  1.000 37.00908 ?  200 ASP   B C   1 
ATOM   3650 O O   . ASP   B 1 220 ? -8.93206  19.46446  56.78891  1.000 33.95051 ?  200 ASP   B O   1 
ATOM   3651 C CB  . ASP   B 1 220 ? -7.68332  19.30925  59.39368  1.000 39.84122 ?  200 ASP   B CB  1 
ATOM   3652 C CG  . ASP   B 1 220 ? -6.52957  20.25615  59.13252  1.000 42.67936 ?  200 ASP   B CG  1 
ATOM   3653 O OD1 . ASP   B 1 220 ? -5.47105  19.79343  58.65719  1.000 44.31425 ?  200 ASP   B OD1 1 
ATOM   3654 O OD2 . ASP   B 1 220 ? -6.68389  21.46615  59.40077  1.000 43.92968 ?  200 ASP   B OD2 1 
ATOM   3655 N N   . LEU   B 1 221 ? -7.11747  18.38233  56.01846  1.000 40.61830 ?  201 LEU   B N   1 
ATOM   3656 C CA  . LEU   B 1 221 ? -7.26197  18.87368  54.65181  1.000 36.67524 ?  201 LEU   B CA  1 
ATOM   3657 C C   . LEU   B 1 221 ? -7.98111  17.85982  53.76905  1.000 36.17009 ?  201 LEU   B C   1 
ATOM   3658 O O   . LEU   B 1 221 ? -9.03958  18.15666  53.20747  1.000 37.56136 ?  201 LEU   B O   1 
ATOM   3659 C CB  . LEU   B 1 221 ? -5.88325  19.22027  54.07838  1.000 36.49864 ?  201 LEU   B CB  1 
ATOM   3660 C CG  . LEU   B 1 221 ? -5.12323  20.28352  54.87404  1.000 39.01352 ?  201 LEU   B CG  1 
ATOM   3661 C CD1 . LEU   B 1 221 ? -3.89496  20.74184  54.11346  1.000 37.99957 ?  201 LEU   B CD1 1 
ATOM   3662 C CD2 . LEU   B 1 221 ? -6.02816  21.46420  55.20965  1.000 35.22059 ?  201 LEU   B CD2 1 
ATOM   3663 N N   . ASN   B 1 222 ? -7.41909  16.66352  53.63653  1.000 36.57330 ?  202 ASN   B N   1 
ATOM   3664 C CA  . ASN   B 1 222 ? -8.11716  15.54564  53.01933  1.000 32.58366 ?  202 ASN   B CA  1 
ATOM   3665 C C   . ASN   B 1 222 ? -8.42261  14.53297  54.11561  1.000 34.06164 ?  202 ASN   B C   1 
ATOM   3666 O O   . ASN   B 1 222 ? -7.73388  13.51017  54.22352  1.000 33.10967 ?  202 ASN   B O   1 
ATOM   3667 C CB  . ASN   B 1 222 ? -7.27827  14.91589  51.90626  1.000 35.76045 ?  202 ASN   B CB  1 
ATOM   3668 C CG  . ASN   B 1 222 ? -7.01492  15.87399  50.75949  1.000 34.47300 ?  202 ASN   B CG  1 
ATOM   3669 O OD1 . ASN   B 1 222 ? -7.94034  16.44667  50.18681  1.000 31.80105 ?  202 ASN   B OD1 1 
ATOM   3670 N ND2 . ASN   B 1 222 ? -5.74472  16.04787  50.41584  1.000 31.96661 ?  202 ASN   B ND2 1 
ATOM   3671 N N   . PRO   B 1 223 ? -9.44454  14.78245  54.94340  1.000 34.21009 ?  203 PRO   B N   1 
ATOM   3672 C CA  . PRO   B 1 223 ? -9.59332  13.99143  56.17908  1.000 35.31586 ?  203 PRO   B CA  1 
ATOM   3673 C C   . PRO   B 1 223 ? -9.77823  12.50460  55.93734  1.000 31.99242 ?  203 PRO   B C   1 
ATOM   3674 O O   . PRO   B 1 223 ? -9.15492  11.69009  56.63086  1.000 26.10398 ?  203 PRO   B O   1 
ATOM   3675 C CB  . PRO   B 1 223 ? -10.82783 14.61356  56.85069  1.000 35.05547 ?  203 PRO   B CB  1 
ATOM   3676 C CG  . PRO   B 1 223 ? -11.53006 15.37093  55.77931  1.000 34.76299 ?  203 PRO   B CG  1 
ATOM   3677 C CD  . PRO   B 1 223 ? -10.48937 15.81022  54.80455  1.000 40.28134 ?  203 PRO   B CD  1 
ATOM   3678 N N   . GLN   B 1 224 ? -10.61639 12.12161  54.97142  1.000 34.45673 ?  204 GLN   B N   1 
ATOM   3679 C CA  . GLN   B 1 224 ? -10.84090 10.70021  54.73677  1.000 36.91921 ?  204 GLN   B CA  1 
ATOM   3680 C C   . GLN   B 1 224 ? -9.63399  10.04684  54.07470  1.000 28.88466 ?  204 GLN   B C   1 
ATOM   3681 O O   . GLN   B 1 224 ? -9.33491  8.88031   54.35319  1.000 29.92500 ?  204 GLN   B O   1 
ATOM   3682 C CB  . GLN   B 1 224 ? -12.10403 10.49403  53.89675  1.000 34.12449 ?  204 GLN   B CB  1 
ATOM   3683 C CG  . GLN   B 1 224 ? -12.47018 9.03292   53.67783  1.000 38.16368 ?  204 GLN   B CG  1 
ATOM   3684 C CD  . GLN   B 1 224 ? -12.92146 8.34559   54.94912  1.000 41.09936 ?  204 GLN   B CD  1 
ATOM   3685 O OE1 . GLN   B 1 224 ? -12.35461 7.33105   55.35600  1.000 41.55090 ?  204 GLN   B OE1 1 
ATOM   3686 N NE2 . GLN   B 1 224 ? -13.94931 8.89380   55.58332  1.000 51.71238 ?  204 GLN   B NE2 1 
ATOM   3687 N N   . LEU   B 1 225 ? -8.92178  10.77770  53.21308  1.000 29.31352 ?  205 LEU   B N   1 
ATOM   3688 C CA  . LEU   B 1 225 ? -7.69950  10.23274  52.63015  1.000 31.48194 ?  205 LEU   B CA  1 
ATOM   3689 C C   . LEU   B 1 225 ? -6.62315  10.03721  53.68956  1.000 33.42785 ?  205 LEU   B C   1 
ATOM   3690 O O   . LEU   B 1 225 ? -5.91678  9.02080   53.68824  1.000 27.32071 ?  205 LEU   B O   1 
ATOM   3691 C CB  . LEU   B 1 225 ? -7.18764  11.14513  51.51609  1.000 32.58294 ?  205 LEU   B CB  1 
ATOM   3692 C CG  . LEU   B 1 225 ? -5.94828  10.62865  50.77232  1.000 28.14642 ?  205 LEU   B CG  1 
ATOM   3693 C CD1 . LEU   B 1 225 ? -6.25415  9.34466   50.00724  1.000 27.76949 ?  205 LEU   B CD1 1 
ATOM   3694 C CD2 . LEU   B 1 225 ? -5.37997  11.69330  49.84312  1.000 39.49419 ?  205 LEU   B CD2 1 
ATOM   3695 N N   . ALA   B 1 226 ? -6.47610  11.00669  54.59640  1.000 23.35823 ?  206 ALA   B N   1 
ATOM   3696 C CA  . ALA   B 1 226 ? -5.50388  10.86746  55.67395  1.000 28.31119 ?  206 ALA   B CA  1 
ATOM   3697 C C   . ALA   B 1 226 ? -5.85617  9.69619   56.58111  1.000 24.72905 ?  206 ALA   B C   1 
ATOM   3698 O O   . ALA   B 1 226 ? -4.97370  8.93383   56.99145  1.000 29.22337 ?  206 ALA   B O   1 
ATOM   3699 C CB  . ALA   B 1 226 ? -5.41746  12.16837  56.47419  1.000 29.14331 ?  206 ALA   B CB  1 
ATOM   3700 N N   . THR   B 1 227 ? -7.14413  9.53137   56.89685  1.000 26.16310 ?  207 THR   B N   1 
ATOM   3701 C CA  . THR   B 1 227 ? -7.56643  8.40109   57.71842  1.000 29.88973 ?  207 THR   B CA  1 
ATOM   3702 C C   . THR   B 1 227 ? -7.25491  7.07756   57.03051  1.000 30.55421 ?  207 THR   B C   1 
ATOM   3703 O O   . THR   B 1 227 ? -6.77473  6.13406   57.67045  1.000 29.53112 ?  207 THR   B O   1 
ATOM   3704 C CB  . THR   B 1 227 ? -9.06229  8.50705   58.03220  1.000 29.62373 ?  207 THR   B CB  1 
ATOM   3705 O OG1 . THR   B 1 227 ? -9.26707  9.43421   59.10551  1.000 32.88484 ?  207 THR   B OG1 1 
ATOM   3706 C CG2 . THR   B 1 227 ? -9.62908  7.14986   58.43427  1.000 33.58800 ?  207 THR   B CG2 1 
ATOM   3707 N N   . ASP   B 1 228 ? -7.50576  6.99717   55.72078  1.000 27.40400 ?  208 ASP   B N   1 
ATOM   3708 C CA  . ASP   B 1 228 ? -7.22280  5.77103   54.98241  1.000 24.25954 ?  208 ASP   B CA  1 
ATOM   3709 C C   . ASP   B 1 228 ? -5.73659  5.44270   55.00256  1.000 30.68714 ?  208 ASP   B C   1 
ATOM   3710 O O   . ASP   B 1 228 ? -5.35097  4.28576   55.20822  1.000 23.01297 ?  208 ASP   B O   1 
ATOM   3711 C CB  . ASP   B 1 228 ? -7.71557  5.90233   53.54266  1.000 24.66451 ?  208 ASP   B CB  1 
ATOM   3712 C CG  . ASP   B 1 228 ? -9.22283  5.93938   53.44482  1.000 23.55901 ?  208 ASP   B CG  1 
ATOM   3713 O OD1 . ASP   B 1 228 ? -9.88871  5.82188   54.49319  1.000 26.66265 ?  208 ASP   B OD1 1 
ATOM   3714 O OD2 . ASP   B 1 228 ? -9.74152  6.09610   52.31981  1.000 27.88038 ?  208 ASP   B OD2 1 
ATOM   3715 N N   . VAL   B 1 229 ? -4.88698  6.44809   54.78717  1.000 23.05292 ?  209 VAL   B N   1 
ATOM   3716 C CA  . VAL   B 1 229 ? -3.44877  6.20925   54.76081  1.000 24.18941 ?  209 VAL   B CA  1 
ATOM   3717 C C   . VAL   B 1 229 ? -2.93722  5.87402   56.15550  1.000 29.65918 ?  209 VAL   B C   1 
ATOM   3718 O O   . VAL   B 1 229 ? -2.10277  4.97710   56.32562  1.000 25.87300 ?  209 VAL   B O   1 
ATOM   3719 C CB  . VAL   B 1 229 ? -2.71999  7.42612   54.16342  1.000 22.90564 ?  209 VAL   B CB  1 
ATOM   3720 C CG1 . VAL   B 1 229 ? -1.21941  7.31775   54.39510  1.000 17.84843 ?  209 VAL   B CG1 1 
ATOM   3721 C CG2 . VAL   B 1 229 ? -3.02832  7.54973   52.67977  1.000 23.06586 ?  209 VAL   B CG2 1 
ATOM   3722 N N   . LEU   B 1 230 ? -3.43091  6.58070   57.17587  1.000 28.58322 ?  210 LEU   B N   1 
ATOM   3723 C CA  . LEU   B 1 230 ? -2.99031  6.30950   58.54016  1.000 29.69403 ?  210 LEU   B CA  1 
ATOM   3724 C C   . LEU   B 1 230 ? -3.44485  4.93800   59.01906  1.000 29.69796 ?  210 LEU   B C   1 
ATOM   3725 O O   . LEU   B 1 230 ? -2.75257  4.30517   59.82420  1.000 31.83144 ?  210 LEU   B O   1 
ATOM   3726 C CB  . LEU   B 1 230 ? -3.50177  7.39331   59.48724  1.000 32.86119 ?  210 LEU   B CB  1 
ATOM   3727 C CG  . LEU   B 1 230 ? -2.82181  8.75491   59.34702  1.000 40.47523 ?  210 LEU   B CG  1 
ATOM   3728 C CD1 . LEU   B 1 230 ? -3.60486  9.83232   60.08472  1.000 32.20700 ?  210 LEU   B CD1 1 
ATOM   3729 C CD2 . LEU   B 1 230 ? -1.38462  8.68275   59.83669  1.000 40.53531 ?  210 LEU   B CD2 1 
ATOM   3730 N N   . LYS   B 1 231 ? -4.59983  4.46588   58.54465  1.000 25.90790 ?  211 LYS   B N   1 
ATOM   3731 C CA  . LYS   B 1 231 ? -5.06738  3.13603   58.91347  1.000 30.12621 ?  211 LYS   B CA  1 
ATOM   3732 C C   . LYS   B 1 231 ? -4.21388  2.03459   58.30039  1.000 35.31207 ?  211 LYS   B C   1 
ATOM   3733 O O   . LYS   B 1 231 ? -4.20032  0.91520   58.82283  1.000 37.43829 ?  211 LYS   B O   1 
ATOM   3734 C CB  . LYS   B 1 231 ? -6.52731  2.95523   58.49565  1.000 29.21382 ?  211 LYS   B CB  1 
ATOM   3735 N N   . ALA   B 1 232 ? -3.50708  2.32239   57.20762  1.000 29.82523 ?  212 ALA   B N   1 
ATOM   3736 C CA  . ALA   B 1 232 ? -2.63078  1.33834   56.58781  1.000 28.73394 ?  212 ALA   B CA  1 
ATOM   3737 C C   . ALA   B 1 232 ? -1.27400  1.24149   57.27084  1.000 30.66346 ?  212 ALA   B C   1 
ATOM   3738 O O   . ALA   B 1 232 ? -0.53336  0.28812   57.00669  1.000 34.78206 ?  212 ALA   B O   1 
ATOM   3739 C CB  . ALA   B 1 232 ? -2.43660  1.66556   55.10502  1.000 26.29526 ?  212 ALA   B CB  1 
ATOM   3740 N N   . LEU   B 1 233 ? -0.93496  2.19332   58.13623  1.000 29.18558 ?  213 LEU   B N   1 
ATOM   3741 C CA  . LEU   B 1 233 ? 0.34718   2.16161   58.81750  1.000 31.29576 ?  213 LEU   B CA  1 
ATOM   3742 C C   . LEU   B 1 233 ? 0.35178   1.08212   59.89976  1.000 30.98737 ?  213 LEU   B C   1 
ATOM   3743 O O   . LEU   B 1 233 ? -0.67120  0.82948   60.54174  1.000 35.59633 ?  213 LEU   B O   1 
ATOM   3744 C CB  . LEU   B 1 233 ? 0.65510   3.52025   59.44164  1.000 30.58860 ?  213 LEU   B CB  1 
ATOM   3745 C CG  . LEU   B 1 233 ? 0.72090   4.71549   58.49059  1.000 33.59513 ?  213 LEU   B CG  1 
ATOM   3746 C CD1 . LEU   B 1 233 ? 1.40941   5.89328   59.15996  1.000 38.06763 ?  213 LEU   B CD1 1 
ATOM   3747 C CD2 . LEU   B 1 233 ? 1.43518   4.33674   57.20787  1.000 28.02216 ?  213 LEU   B CD2 1 
ATOM   3748 N N   . PRO   B 1 234 ? 1.49961   0.42289   60.12103  1.000 27.34364 ?  214 PRO   B N   1 
ATOM   3749 C CA  . PRO   B 1 234 ? 2.73595   0.62931   59.36088  1.000 26.13013 ?  214 PRO   B CA  1 
ATOM   3750 C C   . PRO   B 1 234 ? 2.84603   -0.29329  58.14818  1.000 31.31954 ?  214 PRO   B C   1 
ATOM   3751 O O   . PRO   B 1 234 ? 2.27039   -1.38270  58.15637  1.000 26.83821 ?  214 PRO   B O   1 
ATOM   3752 C CB  . PRO   B 1 234 ? 3.81898   0.30430   60.38696  1.000 26.86175 ?  214 PRO   B CB  1 
ATOM   3753 C CG  . PRO   B 1 234 ? 3.19762   -0.77285  61.22101  1.000 21.90200 ?  214 PRO   B CG  1 
ATOM   3754 C CD  . PRO   B 1 234 ? 1.70689   -0.49350  61.25745  1.000 30.97525 ?  214 PRO   B CD  1 
ATOM   3755 N N   . PHE   B 1 235 ? 3.57182   0.13641   57.11705  1.000 26.46022 ?  215 PHE   B N   1 
ATOM   3756 C CA  . PHE   B 1 235 ? 3.83172   -0.71283  55.96418  1.000 29.33692 ?  215 PHE   B CA  1 
ATOM   3757 C C   . PHE   B 1 235 ? 5.24120   -0.45590  55.45075  1.000 26.65104 ?  215 PHE   B C   1 
ATOM   3758 O O   . PHE   B 1 235 ? 5.82686   0.60650   55.67574  1.000 24.74956 ?  215 PHE   B O   1 
ATOM   3759 C CB  . PHE   B 1 235 ? 2.79120   -0.50660  54.84273  1.000 23.51144 ?  215 PHE   B CB  1 
ATOM   3760 C CG  . PHE   B 1 235 ? 2.75714   0.88927   54.26315  1.000 23.63280 ?  215 PHE   B CG  1 
ATOM   3761 C CD1 . PHE   B 1 235 ? 3.74515   1.33111   53.39379  1.000 23.73622 ?  215 PHE   B CD1 1 
ATOM   3762 C CD2 . PHE   B 1 235 ? 1.71094   1.74650   54.56266  1.000 26.21820 ?  215 PHE   B CD2 1 
ATOM   3763 C CE1 . PHE   B 1 235 ? 3.70334   2.60478   52.85888  1.000 24.87673 ?  215 PHE   B CE1 1 
ATOM   3764 C CE2 . PHE   B 1 235 ? 1.66237   3.02074   54.02510  1.000 20.62643 ?  215 PHE   B CE2 1 
ATOM   3765 C CZ  . PHE   B 1 235 ? 2.66025   3.44985   53.17418  1.000 19.35239 ?  215 PHE   B CZ  1 
ATOM   3766 N N   . THR   B 1 236 ? 5.77894   -1.45532  54.75478  1.000 27.33480 ?  216 THR   B N   1 
ATOM   3767 C CA  . THR   B 1 236 ? 7.08634   -1.37047  54.11502  1.000 26.48900 ?  216 THR   B CA  1 
ATOM   3768 C C   . THR   B 1 236 ? 6.93633   -1.84681  52.67928  1.000 28.61814 ?  216 THR   B C   1 
ATOM   3769 O O   . THR   B 1 236 ? 6.56159   -2.99993  52.44393  1.000 30.99516 ?  216 THR   B O   1 
ATOM   3770 C CB  . THR   B 1 236 ? 8.12962   -2.21025  54.85923  1.000 28.69737 ?  216 THR   B CB  1 
ATOM   3771 O OG1 . THR   B 1 236 ? 8.34074   -1.66352  56.16752  1.000 27.30748 ?  216 THR   B OG1 1 
ATOM   3772 C CG2 . THR   B 1 236 ? 9.44878   -2.22130  54.09981  1.000 27.97274 ?  216 THR   B CG2 1 
ATOM   3773 N N   . VAL   B 1 237 ? 7.21834   -0.96164  51.72282  1.000 25.92079 ?  217 VAL   B N   1 
ATOM   3774 C CA  . VAL   B 1 237 ? 6.99046   -1.23131  50.30897  1.000 30.13410 ?  217 VAL   B CA  1 
ATOM   3775 C C   . VAL   B 1 237 ? 8.21079   -0.79173  49.50925  1.000 27.45292 ?  217 VAL   B C   1 
ATOM   3776 O O   . VAL   B 1 237 ? 9.11665   -0.12945  50.01913  1.000 28.99944 ?  217 VAL   B O   1 
ATOM   3777 C CB  . VAL   B 1 237 ? 5.72197   -0.52681  49.78160  1.000 25.22443 ?  217 VAL   B CB  1 
ATOM   3778 C CG1 . VAL   B 1 237 ? 4.47176   -1.16250  50.37467  1.000 22.23817 ?  217 VAL   B CG1 1 
ATOM   3779 C CG2 . VAL   B 1 237 ? 5.76933   0.95389   50.11059  1.000 26.84981 ?  217 VAL   B CG2 1 
ATOM   3780 N N   . LEU   B 1 238 ? 8.22219   -1.18156  48.23653  1.000 24.47878 ?  218 LEU   B N   1 
ATOM   3781 C CA  . LEU   B 1 238 ? 9.28418   -0.77710  47.32548  1.000 27.81628 ?  218 LEU   B CA  1 
ATOM   3782 C C   . LEU   B 1 238 ? 9.17467   0.70942   47.01316  1.000 26.23160 ?  218 LEU   B C   1 
ATOM   3783 O O   . LEU   B 1 238 ? 8.09433   1.20630   46.68198  1.000 23.56705 ?  218 LEU   B O   1 
ATOM   3784 C CB  . LEU   B 1 238 ? 9.20743   -1.58878  46.03335  1.000 26.68428 ?  218 LEU   B CB  1 
ATOM   3785 C CG  . LEU   B 1 238 ? 10.51829  -1.88864  45.30472  1.000 33.09316 ?  218 LEU   B CG  1 
ATOM   3786 C CD1 . LEU   B 1 238 ? 11.62094  -2.24206  46.29130  1.000 28.24919 ?  218 LEU   B CD1 1 
ATOM   3787 C CD2 . LEU   B 1 238 ? 10.31777  -3.00093  44.28588  1.000 27.97790 ?  218 LEU   B CD2 1 
ATOM   3788 N N   . GLN   B 1 239 ? 10.29422  1.41877   47.11345  1.000 27.92900 ?  219 GLN   B N   1 
ATOM   3789 C CA  . GLN   B 1 239 ? 10.35400  2.83555   46.78174  1.000 25.30630 ?  219 GLN   B CA  1 
ATOM   3790 C C   . GLN   B 1 239 ? 10.93722  2.99938   45.38504  1.000 27.77024 ?  219 GLN   B C   1 
ATOM   3791 O O   . GLN   B 1 239 ? 12.02649  2.49164   45.09696  1.000 28.92421 ?  219 GLN   B O   1 
ATOM   3792 C CB  . GLN   B 1 239 ? 11.19215  3.60507   47.80310  1.000 25.00513 ?  219 GLN   B CB  1 
ATOM   3793 C CG  . GLN   B 1 239 ? 11.37558  5.07655   47.47279  1.000 21.04994 ?  219 GLN   B CG  1 
ATOM   3794 C CD  . GLN   B 1 239 ? 10.11093  5.88709   47.67646  1.000 23.37212 ?  219 GLN   B CD  1 
ATOM   3795 O OE1 . GLN   B 1 239 ? 9.80982   6.31960   48.78853  1.000 24.03984 ?  219 GLN   B OE1 1 
ATOM   3796 N NE2 . GLN   B 1 239 ? 9.36552   6.10271   46.59842  1.000 23.78984 ?  219 GLN   B NE2 1 
ATOM   3797 N N   . ASP   B 1 240 ? 10.21057  3.70405   44.52297  1.000 25.04812 ?  220 ASP   B N   1 
ATOM   3798 C CA  . ASP   B 1 240 ? 10.60624  3.88990   43.13656  1.000 24.03894 ?  220 ASP   B CA  1 
ATOM   3799 C C   . ASP   B 1 240 ? 10.50846  5.36421   42.77307  1.000 23.46504 ?  220 ASP   B C   1 
ATOM   3800 O O   . ASP   B 1 240 ? 9.92936   6.17265   43.50241  1.000 24.75469 ?  220 ASP   B O   1 
ATOM   3801 C CB  . ASP   B 1 240 ? 9.74323   3.04371   42.19210  1.000 22.54636 ?  220 ASP   B CB  1 
ATOM   3802 C CG  . ASP   B 1 240 ? 10.29265  1.64653   42.00090  1.000 27.69839 ?  220 ASP   B CG  1 
ATOM   3803 O OD1 . ASP   B 1 240 ? 11.41506  1.51192   41.46814  1.000 27.65620 ?  220 ASP   B OD1 1 
ATOM   3804 O OD2 . ASP   B 1 240 ? 9.60322   0.68241   42.39284  1.000 27.82514 ?  220 ASP   B OD2 1 
ATOM   3805 N N   . HIS   B 1 241 ? 11.08867  5.70710   41.62808  1.000 23.11594 ?  221 HIS   B N   1 
ATOM   3806 C CA  . HIS   B 1 241 ? 11.15746  7.07966   41.15480  1.000 21.63403 ?  221 HIS   B CA  1 
ATOM   3807 C C   . HIS   B 1 241 ? 10.18353  7.29624   40.00457  1.000 26.63105 ?  221 HIS   B C   1 
ATOM   3808 O O   . HIS   B 1 241 ? 9.88864   6.37827   39.23365  1.000 23.57121 ?  221 HIS   B O   1 
ATOM   3809 C CB  . HIS   B 1 241 ? 12.57915  7.42676   40.69767  1.000 26.75210 ?  221 HIS   B CB  1 
ATOM   3810 C CG  . HIS   B 1 241 ? 12.91724  8.88163   40.80607  1.000 31.04131 ?  221 HIS   B CG  1 
ATOM   3811 N ND1 . HIS   B 1 241 ? 12.40734  9.83072   39.94631  1.000 30.49442 ?  221 HIS   B ND1 1 
ATOM   3812 C CD2 . HIS   B 1 241 ? 13.72456  9.54806   41.66515  1.000 34.80965 ?  221 HIS   B CD2 1 
ATOM   3813 C CE1 . HIS   B 1 241 ? 12.88113  11.01945  40.27449  1.000 34.82460 ?  221 HIS   B CE1 1 
ATOM   3814 N NE2 . HIS   B 1 241 ? 13.68253  10.87582  41.31451  1.000 38.44066 ?  221 HIS   B NE2 1 
ATOM   3815 N N   . ALA   B 1 242 ? 9.67970   8.52236   39.90416  1.000 23.15343 ?  222 ALA   B N   1 
ATOM   3816 C CA  . ALA   B 1 242 ? 8.93469   8.92433   38.72193  1.000 25.59660 ?  222 ALA   B CA  1 
ATOM   3817 C C   . ALA   B 1 242 ? 9.85925   8.92754   37.51202  1.000 26.61804 ?  222 ALA   B C   1 
ATOM   3818 O O   . ALA   B 1 242 ? 11.02923  9.30852   37.60489  1.000 31.21361 ?  222 ALA   B O   1 
ATOM   3819 C CB  . ALA   B 1 242 ? 8.31782   10.30703  38.92027  1.000 24.54697 ?  222 ALA   B CB  1 
ATOM   3820 N N   . VAL   B 1 243 ? 9.33132   8.49300   36.37017  1.000 24.62702 ?  223 VAL   B N   1 
ATOM   3821 C CA  . VAL   B 1 243 ? 10.12635  8.36012   35.15338  1.000 26.49603 ?  223 VAL   B CA  1 
ATOM   3822 C C   . VAL   B 1 243 ? 9.75885   9.37805   34.08509  1.000 26.54226 ?  223 VAL   B C   1 
ATOM   3823 O O   . VAL   B 1 243 ? 10.43750  9.42695   33.04368  1.000 21.84634 ?  223 VAL   B O   1 
ATOM   3824 C CB  . VAL   B 1 243 ? 10.03333  6.93225   34.57458  1.000 28.28694 ?  223 VAL   B CB  1 
ATOM   3825 C CG1 . VAL   B 1 243 ? 10.61932  5.92497   35.55449  1.000 23.19945 ?  223 VAL   B CG1 1 
ATOM   3826 C CG2 . VAL   B 1 243 ? 8.59108   6.58626   34.26007  1.000 22.61130 ?  223 VAL   B CG2 1 
ATOM   3827 N N   . VAL   B 1 244 ? 8.73004   10.20136  34.30376  1.000 28.24967 ?  224 VAL   B N   1 
ATOM   3828 C CA  . VAL   B 1 244 ? 8.29392   11.19648  33.33138  1.000 31.35568 ?  224 VAL   B CA  1 
ATOM   3829 C C   . VAL   B 1 244 ? 8.37925   12.60831  33.89712  1.000 28.48528 ?  224 VAL   B C   1 
ATOM   3830 O O   . VAL   B 1 244 ? 8.93583   13.51327  33.26306  1.000 28.81039 ?  224 VAL   B O   1 
ATOM   3831 C CB  . VAL   B 1 244 ? 6.86314   10.90175  32.82499  1.000 24.71976 ?  224 VAL   B CB  1 
ATOM   3832 C CG1 . VAL   B 1 244 ? 6.38931   12.02131  31.91124  1.000 23.45415 ?  224 VAL   B CG1 1 
ATOM   3833 C CG2 . VAL   B 1 244 ? 6.81080   9.56229   32.11017  1.000 23.57066 ?  224 VAL   B CG2 1 
ATOM   3834 N N   . SER   B 1 245 ? 7.83564   12.81749  35.09786  1.000 32.50770 ?  225 SER   B N   1 
ATOM   3835 C CA  . SER   B 1 245 ? 7.57167   14.15311  35.61878  1.000 42.70710 ?  225 SER   B CA  1 
ATOM   3836 C C   . SER   B 1 245 ? 8.62877   14.63765  36.60981  1.000 35.26851 ?  225 SER   B C   1 
ATOM   3837 O O   . SER   B 1 245 ? 8.29900   15.34942  37.56366  1.000 45.93046 ?  225 SER   B O   1 
ATOM   3838 C CB  . SER   B 1 245 ? 6.18926   14.19505  36.26705  1.000 36.85288 ?  225 SER   B CB  1 
ATOM   3839 O OG  . SER   B 1 245 ? 6.19258   13.52584  37.51650  1.000 43.06313 ?  225 SER   B OG  1 
ATOM   3840 N N   . GLY   B 1 246 ? 9.88667   14.27346  36.41389  1.000 40.06556 ?  226 GLY   B N   1 
ATOM   3841 C CA  . GLY   B 1 246 ? 10.97447  14.91537  37.13775  1.000 46.46306 ?  226 GLY   B CA  1 
ATOM   3842 C C   . GLY   B 1 246 ? 11.25067  14.28575  38.49114  1.000 42.05575 ?  226 GLY   B C   1 
ATOM   3843 O O   . GLY   B 1 246 ? 11.31504  13.06084  38.61155  1.000 43.17858 ?  226 GLY   B O   1 
ATOM   3844 N N   . GLU   B 1 247 ? 11.41369  15.13243  39.51072  1.000 30.36996 ?  227 GLU   B N   1 
ATOM   3845 C CA  . GLU   B 1 247 ? 12.03200  14.72428  40.77373  1.000 41.39149 ?  227 GLU   B CA  1 
ATOM   3846 C C   . GLU   B 1 247 ? 10.98007  14.55828  41.87008  1.000 35.09626 ?  227 GLU   B C   1 
ATOM   3847 O O   . GLU   B 1 247 ? 10.83538  15.37697  42.77806  1.000 36.68955 ?  227 GLU   B O   1 
ATOM   3848 C CB  . GLU   B 1 247 ? 13.10801  15.72458  41.17915  1.000 33.07555 ?  227 GLU   B CB  1 
ATOM   3849 C CG  . GLU   B 1 247 ? 14.40390  15.58508  40.40796  1.000 40.96871 ?  227 GLU   B CG  1 
ATOM   3850 C CD  . GLU   B 1 247 ? 15.50464  16.43959  40.99364  1.000 44.40812 ?  227 GLU   B CD  1 
ATOM   3851 O OE1 . GLU   B 1 247 ? 15.18316  17.50929  41.54853  1.000 43.01642 ?  227 GLU   B OE1 1 
ATOM   3852 O OE2 . GLU   B 1 247 ? 16.68565  16.03651  40.91334  1.000 51.32280 ?  227 GLU   B OE2 1 
ATOM   3853 N N   . SER   B 1 248 ? 10.24368  13.45469  41.75841  1.000 34.10252 ?  228 SER   B N   1 
ATOM   3854 C CA  . SER   B 1 248 ? 9.41839   12.92248  42.83110  1.000 28.22452 ?  228 SER   B CA  1 
ATOM   3855 C C   . SER   B 1 248 ? 9.55255   11.40686  42.82573  1.000 30.97375 ?  228 SER   B C   1 
ATOM   3856 O O   . SER   B 1 248 ? 9.89289   10.79673  41.80752  1.000 33.70333 ?  228 SER   B O   1 
ATOM   3857 C CB  . SER   B 1 248 ? 7.93493   13.31589  42.69035  1.000 30.16486 ?  228 SER   B CB  1 
ATOM   3858 O OG  . SER   B 1 248 ? 7.40819   12.93551  41.43124  1.000 33.06327 ?  228 SER   B OG  1 
ATOM   3859 N N   . MET   B 1 249 ? 9.29332   10.80445  43.98313  1.000 28.96194 ?  229 MET   B N   1 
ATOM   3860 C CA  . MET   B 1 249 ? 9.29874   9.35823   44.13210  1.000 25.37776 ?  229 MET   B CA  1 
ATOM   3861 C C   . MET   B 1 249 ? 7.99234   8.91442   44.76973  1.000 20.86780 ?  229 MET   B C   1 
ATOM   3862 O O   . MET   B 1 249 ? 7.45490   9.58748   45.65298  1.000 27.74995 ?  229 MET   B O   1 
ATOM   3863 C CB  . MET   B 1 249 ? 10.48180  8.88258   44.97868  1.000 26.78745 ?  229 MET   B CB  1 
ATOM   3864 C CG  . MET   B 1 249 ? 10.82452  9.78914   46.13793  1.000 29.90697 ?  229 MET   B CG  1 
ATOM   3865 S SD  . MET   B 1 249 ? 12.44117  9.36517   46.80141  1.000 36.45575 ?  229 MET   B SD  1 
ATOM   3866 C CE  . MET   B 1 249 ? 12.12858  9.57878   48.54690  1.000 25.07877 ?  229 MET   B CE  1 
ATOM   3867 N N   . TYR   B 1 250 ? 7.48247   7.77438   44.31199  1.000 26.33651 ?  230 TYR   B N   1 
ATOM   3868 C CA  . TYR   B 1 250 ? 6.22952   7.24518   44.82422  1.000 21.47568 ?  230 TYR   B CA  1 
ATOM   3869 C C   . TYR   B 1 250 ? 6.38489   5.76079   45.11606  1.000 26.41641 ?  230 TYR   B C   1 
ATOM   3870 O O   . TYR   B 1 250 ? 7.26423   5.08487   44.57696  1.000 27.15070 ?  230 TYR   B O   1 
ATOM   3871 C CB  . TYR   B 1 250 ? 5.06309   7.48420   43.84996  1.000 20.13391 ?  230 TYR   B CB  1 
ATOM   3872 C CG  . TYR   B 1 250 ? 5.38392   7.24278   42.38775  1.000 26.43251 ?  230 TYR   B CG  1 
ATOM   3873 C CD1 . TYR   B 1 250 ? 5.76324   5.98491   41.93266  1.000 18.82627 ?  230 TYR   B CD1 1 
ATOM   3874 C CD2 . TYR   B 1 250 ? 5.28545   8.27059   41.45802  1.000 27.30177 ?  230 TYR   B CD2 1 
ATOM   3875 C CE1 . TYR   B 1 250 ? 6.04608   5.76119   40.59556  1.000 20.51637 ?  230 TYR   B CE1 1 
ATOM   3876 C CE2 . TYR   B 1 250 ? 5.56687   8.05660   40.11952  1.000 24.43991 ?  230 TYR   B CE2 1 
ATOM   3877 C CZ  . TYR   B 1 250 ? 5.94630   6.80164   39.69376  1.000 26.22936 ?  230 TYR   B CZ  1 
ATOM   3878 O OH  . TYR   B 1 250 ? 6.22622   6.59088   38.36198  1.000 25.76124 ?  230 TYR   B OH  1 
ATOM   3879 N N   . ALA   B 1 251 ? 5.51234   5.26334   45.98648  1.000 26.77919 ?  231 ALA   B N   1 
ATOM   3880 C CA  . ALA   B 1 251 ? 5.50051   3.86097   46.36913  1.000 26.45279 ?  231 ALA   B CA  1 
ATOM   3881 C C   . ALA   B 1 251 ? 4.05525   3.40572   46.46390  1.000 25.64610 ?  231 ALA   B C   1 
ATOM   3882 O O   . ALA   B 1 251 ? 3.24855   4.04287   47.14713  1.000 21.21306 ?  231 ALA   B O   1 
ATOM   3883 C CB  . ALA   B 1 251 ? 6.22277   3.64338   47.70395  1.000 27.83950 ?  231 ALA   B CB  1 
ATOM   3884 N N   . TRP   B 1 252 ? 3.72742   2.32531   45.76129  1.000 22.94633 ?  232 TRP   B N   1 
ATOM   3885 C CA  . TRP   B 1 252 ? 2.38923   1.75731   45.84569  1.000 23.65461 ?  232 TRP   B CA  1 
ATOM   3886 C C   . TRP   B 1 252 ? 2.11060   1.29967   47.27208  1.000 27.81425 ?  232 TRP   B C   1 
ATOM   3887 O O   . TRP   B 1 252 ? 2.76810   0.38590   47.77980  1.000 23.78739 ?  232 TRP   B O   1 
ATOM   3888 C CB  . TRP   B 1 252 ? 2.25184   0.58929   44.87003  1.000 20.59606 ?  232 TRP   B CB  1 
ATOM   3889 C CG  . TRP   B 1 252 ? 2.07569   0.98957   43.42706  1.000 25.22914 ?  232 TRP   B CG  1 
ATOM   3890 C CD1 . TRP   B 1 252 ? 0.91662   0.95584   42.70687  1.000 24.07481 ?  232 TRP   B CD1 1 
ATOM   3891 C CD2 . TRP   B 1 252 ? 3.09111   1.46289   42.52811  1.000 17.91630 ?  232 TRP   B CD2 1 
ATOM   3892 N NE1 . TRP   B 1 252 ? 1.14413   1.38285   41.42094  1.000 22.52734 ?  232 TRP   B NE1 1 
ATOM   3893 C CE2 . TRP   B 1 252 ? 2.47042   1.69745   41.28419  1.000 21.94639 ?  232 TRP   B CE2 1 
ATOM   3894 C CE3 . TRP   B 1 252 ? 4.46255   1.70872   42.65389  1.000 22.22122 ?  232 TRP   B CE3 1 
ATOM   3895 C CZ2 . TRP   B 1 252 ? 3.17114   2.17104   40.17641  1.000 17.24277 ?  232 TRP   B CZ2 1 
ATOM   3896 C CZ3 . TRP   B 1 252 ? 5.15763   2.17757   41.55027  1.000 23.30959 ?  232 TRP   B CZ3 1 
ATOM   3897 C CH2 . TRP   B 1 252 ? 4.50972   2.40415   40.32852  1.000 21.45480 ?  232 TRP   B CH2 1 
ATOM   3898 N N   . ALA   B 1 253 ? 1.13020   1.94861   47.92682  1.000 25.10478 ?  233 ALA   B N   1 
ATOM   3899 C CA  . ALA   B 1 253 ? 0.79777   1.66367   49.31454  1.000 24.69003 ?  233 ALA   B CA  1 
ATOM   3900 C C   . ALA   B 1 253 ? -0.27293  0.57884   49.40484  1.000 24.99959 ?  233 ALA   B C   1 
ATOM   3901 O O   . ALA   B 1 253 ? -1.12599  0.46289   48.51883  1.000 26.45714 ?  233 ALA   B O   1 
ATOM   3902 C CB  . ALA   B 1 253 ? 0.31109   2.93025   50.01361  1.000 25.92428 ?  233 ALA   B CB  1 
ATOM   3903 N N   . PRO   B 1 254 ? -0.25055  -0.23634  50.46790  1.000 28.55009 ?  234 PRO   B N   1 
ATOM   3904 C CA  . PRO   B 1 254 ? -1.18494  -1.38102  50.56659  1.000 24.96093 ?  234 PRO   B CA  1 
ATOM   3905 C C   . PRO   B 1 254 ? -2.58907  -0.97609  51.00166  1.000 24.34063 ?  234 PRO   B C   1 
ATOM   3906 O O   . PRO   B 1 254 ? -3.05691  -1.28411  52.10413  1.000 25.40288 ?  234 PRO   B O   1 
ATOM   3907 C CB  . PRO   B 1 254 ? -0.48751  -2.28088  51.59225  1.000 23.07046 ?  234 PRO   B CB  1 
ATOM   3908 C CG  . PRO   B 1 254 ? 0.23062   -1.32670  52.47902  1.000 27.13115 ?  234 PRO   B CG  1 
ATOM   3909 C CD  . PRO   B 1 254 ? 0.71577   -0.21757  51.58133  1.000 26.37028 ?  234 PRO   B CD  1 
ATOM   3910 N N   . LEU   B 1 255 ? -3.28958  -0.27717  50.11124  1.000 23.72311 ?  235 LEU   B N   1 
ATOM   3911 C CA  . LEU   B 1 255 ? -4.67900  0.10598   50.33164  1.000 23.56290 ?  235 LEU   B CA  1 
ATOM   3912 C C   . LEU   B 1 255 ? -5.24690  0.62857   49.02184  1.000 24.09157 ?  235 LEU   B C   1 
ATOM   3913 O O   . LEU   B 1 255 ? -4.50472  0.98942   48.10429  1.000 21.78914 ?  235 LEU   B O   1 
ATOM   3914 C CB  . LEU   B 1 255 ? -4.81979  1.16876   51.42845  1.000 24.64641 ?  235 LEU   B CB  1 
ATOM   3915 C CG  . LEU   B 1 255 ? -4.58882  2.62349   51.01271  1.000 30.54232 ?  235 LEU   B CG  1 
ATOM   3916 C CD1 . LEU   B 1 255 ? -5.32792  3.56020   51.94931  1.000 30.45213 ?  235 LEU   B CD1 1 
ATOM   3917 C CD2 . LEU   B 1 255 ? -3.10924  2.95548   50.99381  1.000 26.58246 ?  235 LEU   B CD2 1 
ATOM   3918 N N   . VAL   B 1 256 ? -6.57521  0.66363   48.94872  1.000 24.77906 ?  236 VAL   B N   1 
ATOM   3919 C CA  . VAL   B 1 256 ? -7.29955  1.24776   47.82329  1.000 22.03132 ?  236 VAL   B CA  1 
ATOM   3920 C C   . VAL   B 1 256 ? -8.26747  2.26108   48.42031  1.000 23.24783 ?  236 VAL   B C   1 
ATOM   3921 O O   . VAL   B 1 256 ? -9.33608  1.89138   48.92044  1.000 32.18289 ?  236 VAL   B O   1 
ATOM   3922 C CB  . VAL   B 1 256 ? -8.03820  0.19875   46.98443  1.000 23.25496 ?  236 VAL   B CB  1 
ATOM   3923 C CG1 . VAL   B 1 256 ? -8.82354  0.86674   45.86190  1.000 19.39450 ?  236 VAL   B CG1 1 
ATOM   3924 C CG2 . VAL   B 1 256 ? -7.05652  -0.81125  46.41508  1.000 17.58971 ?  236 VAL   B CG2 1 
ATOM   3925 N N   . SER   B 1 257 ? -7.89633  3.53684   48.37871  1.000 17.98431 ?  237 SER   B N   1 
ATOM   3926 C CA  . SER   B 1 257 ? -8.70517  4.59741   48.95952  1.000 23.51878 ?  237 SER   B CA  1 
ATOM   3927 C C   . SER   B 1 257 ? -9.66847  5.15150   47.91812  1.000 27.55849 ?  237 SER   B C   1 
ATOM   3928 O O   . SER   B 1 257 ? -9.25093  5.56307   46.83062  1.000 28.22822 ?  237 SER   B O   1 
ATOM   3929 C CB  . SER   B 1 257 ? -7.81507  5.71544   49.50508  1.000 21.39753 ?  237 SER   B CB  1 
ATOM   3930 O OG  . SER   B 1 257 ? -8.58491  6.83909   49.89532  1.000 19.61605 ?  237 SER   B OG  1 
ATOM   3931 N N   . VAL   B 1 258 ? -10.95518 5.14535   48.25081  1.000 25.38366 ?  238 VAL   B N   1 
ATOM   3932 C CA  . VAL   B 1 258 ? -11.96807 5.82808   47.45994  1.000 29.04190 ?  238 VAL   B CA  1 
ATOM   3933 C C   . VAL   B 1 258 ? -12.33046 7.17866   48.07916  1.000 28.92217 ?  238 VAL   B C   1 
ATOM   3934 O O   . VAL   B 1 258 ? -13.38634 7.73562   47.78192  1.000 29.57376 ?  238 VAL   B O   1 
ATOM   3935 C CB  . VAL   B 1 258 ? -13.21559 4.95406   47.26524  1.000 28.36635 ?  238 VAL   B CB  1 
ATOM   3936 C CG1 . VAL   B 1 258 ? -12.87412 3.71883   46.44471  1.000 31.65676 ?  238 VAL   B CG1 1 
ATOM   3937 C CG2 . VAL   B 1 258 ? -13.80223 4.56256   48.61337  1.000 26.59165 ?  238 VAL   B CG2 1 
ATOM   3938 N N   . ALA   B 1 259 ? -11.46673 7.70738   48.94020  1.000 20.83216 ?  239 ALA   B N   1 
ATOM   3939 C CA  . ALA   B 1 259 ? -11.74406 8.95676   49.62291  1.000 29.15709 ?  239 ALA   B CA  1 
ATOM   3940 C C   . ALA   B 1 259 ? -11.77321 10.12068  48.63389  1.000 28.70922 ?  239 ALA   B C   1 
ATOM   3941 O O   . ALA   B 1 259 ? -11.09811 10.08731  47.60163  1.000 26.09407 ?  239 ALA   B O   1 
ATOM   3942 C CB  . ALA   B 1 259 ? -10.68603 9.21972   50.68941  1.000 25.40343 ?  239 ALA   B CB  1 
ATOM   3943 N N   . PRO   B 1 260 ? -12.55242 11.15926  48.92394  1.000 28.43466 ?  240 PRO   B N   1 
ATOM   3944 C CA  . PRO   B 1 260 ? -12.46242 12.38801  48.13135  1.000 27.46486 ?  240 PRO   B CA  1 
ATOM   3945 C C   . PRO   B 1 260 ? -11.11031 13.05562  48.32450  1.000 29.08529 ?  240 PRO   B C   1 
ATOM   3946 O O   . PRO   B 1 260 ? -10.42955 12.87006  49.33504  1.000 25.60511 ?  240 PRO   B O   1 
ATOM   3947 C CB  . PRO   B 1 260 ? -13.59814 13.25623  48.68402  1.000 33.28955 ?  240 PRO   B CB  1 
ATOM   3948 C CG  . PRO   B 1 260 ? -13.82625 12.73946  50.06867  1.000 33.25458 ?  240 PRO   B CG  1 
ATOM   3949 C CD  . PRO   B 1 260 ? -13.54499 11.26629  50.00762  1.000 28.12121 ?  240 PRO   B CD  1 
ATOM   3950 N N   . THR   B 1 261 ? -10.72150 13.84488  47.32713  1.000 30.99120 ?  241 THR   B N   1 
ATOM   3951 C CA  . THR   B 1 261 ? -9.43335  14.53984  47.32711  1.000 26.52757 ?  241 THR   B CA  1 
ATOM   3952 C C   . THR   B 1 261 ? -9.64250  16.02619  47.05717  1.000 33.64280 ?  241 THR   B C   1 
ATOM   3953 O O   . THR   B 1 261 ? -9.19809  16.55610  46.03450  1.000 28.86483 ?  241 THR   B O   1 
ATOM   3954 C CB  . THR   B 1 261 ? -8.49772  13.91902  46.29242  1.000 29.77309 ?  241 THR   B CB  1 
ATOM   3955 O OG1 . THR   B 1 261 ? -9.18866  13.79426  45.04372  1.000 24.62863 ?  241 THR   B OG1 1 
ATOM   3956 C CG2 . THR   B 1 261 ? -8.05471  12.53539  46.74706  1.000 29.66988 ?  241 THR   B CG2 1 
ATOM   3957 N N   . PRO   B 1 262 ? -10.31556 16.73727  47.96905  1.000 32.86585 ?  242 PRO   B N   1 
ATOM   3958 C CA  . PRO   B 1 262 ? -10.62940 18.14741  47.68605  1.000 35.93216 ?  242 PRO   B CA  1 
ATOM   3959 C C   . PRO   B 1 262 ? -9.41790  19.06068  47.70766  1.000 32.29388 ?  242 PRO   B C   1 
ATOM   3960 O O   . PRO   B 1 262 ? -9.26547  19.89453  46.80791  1.000 31.47093 ?  242 PRO   B O   1 
ATOM   3961 C CB  . PRO   B 1 262 ? -11.62496 18.50698  48.79655  1.000 34.24221 ?  242 PRO   B CB  1 
ATOM   3962 C CG  . PRO   B 1 262 ? -11.28013 17.58494  49.91078  1.000 31.92763 ?  242 PRO   B CG  1 
ATOM   3963 C CD  . PRO   B 1 262 ? -10.90574 16.29429  49.24508  1.000 29.27461 ?  242 PRO   B CD  1 
ATOM   3964 N N   . VAL   B 1 263 ? -8.55341  18.93941  48.71203  1.000 34.94449 ?  243 VAL   B N   1 
ATOM   3965 C CA  . VAL   B 1 263 ? -7.45835  19.88260  48.91482  1.000 32.57586 ?  243 VAL   B CA  1 
ATOM   3966 C C   . VAL   B 1 263 ? -6.28275  19.42203  48.05793  1.000 38.33027 ?  243 VAL   B C   1 
ATOM   3967 O O   . VAL   B 1 263 ? -5.61036  18.43747  48.37054  1.000 40.74699 ?  243 VAL   B O   1 
ATOM   3968 C CB  . VAL   B 1 263 ? -7.08296  20.00315  50.39219  1.000 37.53378 ?  243 VAL   B CB  1 
ATOM   3969 C CG1 . VAL   B 1 263 ? -5.86878  20.90483  50.55998  1.000 34.38847 ?  243 VAL   B CG1 1 
ATOM   3970 C CG2 . VAL   B 1 263 ? -8.26286  20.54601  51.17916  1.000 32.88506 ?  243 VAL   B CG2 1 
ATOM   3971 N N   . ARG   B 1 264 ? -6.03900  20.14520  46.96730  1.000 37.53100 ?  244 ARG   B N   1 
ATOM   3972 C CA  . ARG   B 1 264 ? -4.96108  19.86112  46.03364  1.000 35.83150 ?  244 ARG   B CA  1 
ATOM   3973 C C   . ARG   B 1 264 ? -4.06894  21.08580  45.88615  1.000 42.25362 ?  244 ARG   B C   1 
ATOM   3974 O O   . ARG   B 1 264 ? -4.51473  22.22684  46.04792  1.000 33.79365 ?  244 ARG   B O   1 
ATOM   3975 C CB  . ARG   B 1 264 ? -5.50686  19.44194  44.66217  1.000 34.26224 ?  244 ARG   B CB  1 
ATOM   3976 C CG  . ARG   B 1 264 ? -6.19955  18.09399  44.68094  1.000 38.54808 ?  244 ARG   B CG  1 
ATOM   3977 C CD  . ARG   B 1 264 ? -7.13989  17.92817  43.50317  1.000 35.38979 ?  244 ARG   B CD  1 
ATOM   3978 N NE  . ARG   B 1 264 ? -7.54674  16.53987  43.31743  1.000 39.39789 ?  244 ARG   B NE  1 
ATOM   3979 C CZ  . ARG   B 1 264 ? -6.79010  15.59869  42.76968  1.000 43.35703 ?  244 ARG   B CZ  1 
ATOM   3980 N NH1 . ARG   B 1 264 ? -5.56893  15.85960  42.33364  1.000 47.44896 ?  244 ARG   B NH1 1 
ATOM   3981 N NH2 . ARG   B 1 264 ? -7.27122  14.36370  42.65719  1.000 48.19066 ?  244 ARG   B NH2 1 
ATOM   3982 N N   . GLU   B 1 265 ? -2.79891  20.83546  45.58342  1.000 39.30121 ?  245 GLU   B N   1 
ATOM   3983 C CA  . GLU   B 1 265 ? -1.80160  21.88463  45.43924  1.000 39.97537 ?  245 GLU   B CA  1 
ATOM   3984 C C   . GLU   B 1 265 ? -1.00704  21.65159  44.16420  1.000 43.36211 ?  245 GLU   B C   1 
ATOM   3985 O O   . GLU   B 1 265 ? -0.67981  20.50962  43.82531  1.000 43.59820 ?  245 GLU   B O   1 
ATOM   3986 C CB  . GLU   B 1 265 ? -0.86772  21.93289  46.66285  1.000 40.14427 ?  245 GLU   B CB  1 
ATOM   3987 C CG  . GLU   B 1 265 ? 0.55929   22.37841  46.37819  1.000 41.28209 ?  245 GLU   B CG  1 
ATOM   3988 C CD  . GLU   B 1 265 ? 1.46701   22.22814  47.58581  1.000 42.45624 ?  245 GLU   B CD  1 
ATOM   3989 O OE1 . GLU   B 1 265 ? 1.99180   21.11574  47.80523  1.000 47.11404 ?  245 GLU   B OE1 1 
ATOM   3990 O OE2 . GLU   B 1 265 ? 1.65705   23.22490  48.31518  1.000 49.18731 ?  245 GLU   B OE2 1 
ATOM   3991 N N   . ARG   B 1 266 ? -0.72327  22.74009  43.45176  1.000 45.49706 ?  246 ARG   B N   1 
ATOM   3992 C CA  . ARG   B 1 266 ? 0.07079   22.65852  42.23470  1.000 49.00220 ?  246 ARG   B CA  1 
ATOM   3993 C C   . ARG   B 1 266 ? 1.42711   22.02724  42.52714  1.000 44.23712 ?  246 ARG   B C   1 
ATOM   3994 O O   . ARG   B 1 266 ? 2.12890   22.43600  43.45738  1.000 46.43232 ?  246 ARG   B O   1 
ATOM   3995 C CB  . ARG   B 1 266 ? 0.24150   24.05210  41.62828  1.000 47.06592 ?  246 ARG   B CB  1 
ATOM   3996 C CG  . ARG   B 1 266 ? -0.20157  24.13600  40.17987  1.000 49.66160 ?  246 ARG   B CG  1 
ATOM   3997 C CD  . ARG   B 1 266 ? -0.50095  25.56208  39.73921  1.000 47.75421 ?  246 ARG   B CD  1 
ATOM   3998 N NE  . ARG   B 1 266 ? 0.68825   26.40481  39.74628  1.000 54.12087 ?  246 ARG   B NE  1 
ATOM   3999 C CZ  . ARG   B 1 266 ? 0.81662   27.52402  39.04686  1.000 53.73071 ?  246 ARG   B CZ  1 
ATOM   4000 N NH1 . ARG   B 1 266 ? -0.15696  27.96875  38.26875  1.000 54.26159 ?  246 ARG   B NH1 1 
ATOM   4001 N NH2 . ARG   B 1 266 ? 1.95472   28.20798  39.12095  1.000 57.15937 ?  246 ARG   B NH2 1 
ATOM   4002 N N   . ILE   B 1 267 ? 1.78237   21.01297  41.73165  1.000 42.18631 ?  247 ILE   B N   1 
ATOM   4003 C CA  . ILE   B 1 267 ? 3.02123   20.26923  41.95587  1.000 46.45152 ?  247 ILE   B CA  1 
ATOM   4004 C C   . ILE   B 1 267 ? 4.22899   21.19423  41.88396  1.000 42.84466 ?  247 ILE   B C   1 
ATOM   4005 O O   . ILE   B 1 267 ? 5.19320   21.04052  42.64530  1.000 34.20404 ?  247 ILE   B O   1 
ATOM   4006 C CB  . ILE   B 1 267 ? 3.13924   19.11194  40.94677  1.000 38.48595 ?  247 ILE   B CB  1 
ATOM   4007 N N   . CYS   B 1 268 ? 4.20061   22.16589  40.96745  1.000 39.94576 ?  248 CYS   B N   1 
ATOM   4008 C CA  . CYS   B 1 268 ? 5.31068   23.10385  40.84649  1.000 42.60494 ?  248 CYS   B CA  1 
ATOM   4009 C C   . CYS   B 1 268 ? 5.46428   23.97758  42.08397  1.000 39.10297 ?  248 CYS   B C   1 
ATOM   4010 O O   . CYS   B 1 268 ? 6.51591   24.59991  42.26422  1.000 37.58799 ?  248 CYS   B O   1 
ATOM   4011 C CB  . CYS   B 1 268 ? 5.12525   23.98272  39.60947  1.000 41.12821 ?  248 CYS   B CB  1 
ATOM   4012 S SG  . CYS   B 1 268 ? 3.62860   24.99371  39.62350  1.000 39.30512 ?  248 CYS   B SG  1 
ATOM   4013 N N   . ASP   B 1 269 ? 4.44674   24.03296  42.94077  1.000 37.91685 ?  249 ASP   B N   1 
ATOM   4014 C CA  . ASP   B 1 269 ? 4.46442   24.86173  44.13739  1.000 37.75797 ?  249 ASP   B CA  1 
ATOM   4015 C C   . ASP   B 1 269 ? 4.69746   24.05956  45.41173  1.000 39.43148 ?  249 ASP   B C   1 
ATOM   4016 O O   . ASP   B 1 269 ? 4.77634   24.65107  46.49283  1.000 38.25231 ?  249 ASP   B O   1 
ATOM   4017 C CB  . ASP   B 1 269 ? 3.15112   25.64400  44.24694  1.000 43.00415 ?  249 ASP   B CB  1 
ATOM   4018 C CG  . ASP   B 1 269 ? 3.07431   26.78748  43.25561  1.000 40.24153 ?  249 ASP   B CG  1 
ATOM   4019 O OD1 . ASP   B 1 269 ? 4.14200   27.31709  42.87763  1.000 39.63442 ?  249 ASP   B OD1 1 
ATOM   4020 O OD2 . ASP   B 1 269 ? 1.95232   27.15273  42.85197  1.000 44.22261 ?  249 ASP   B OD2 1 
ATOM   4021 N N   . ALA   B 1 270 ? 4.81440   22.74004  45.31348  1.000 36.43277 ?  250 ALA   B N   1 
ATOM   4022 C CA  . ALA   B 1 270 ? 4.99813   21.91682  46.50315  1.000 39.44322 ?  250 ALA   B CA  1 
ATOM   4023 C C   . ALA   B 1 270 ? 6.40937   22.09610  47.05361  1.000 35.57934 ?  250 ALA   B C   1 
ATOM   4024 O O   . ALA   B 1 270 ? 7.37628   22.06787  46.28358  1.000 29.52579 ?  250 ALA   B O   1 
ATOM   4025 C CB  . ALA   B 1 270 ? 4.74318   20.44760  46.17610  1.000 36.60993 ?  250 ALA   B CB  1 
ATOM   4026 N N   . PRO   B 1 271 ? 6.57157   22.28234  48.36080  1.000 37.91919 ?  251 PRO   B N   1 
ATOM   4027 C CA  . PRO   B 1 271 ? 7.91679   22.41765  48.92303  1.000 33.54867 ?  251 PRO   B CA  1 
ATOM   4028 C C   . PRO   B 1 271 ? 8.61913   21.07185  49.01474  1.000 41.11795 ?  251 PRO   B C   1 
ATOM   4029 O O   . PRO   B 1 271 ? 8.00882   20.00647  48.90213  1.000 41.12485 ?  251 PRO   B O   1 
ATOM   4030 C CB  . PRO   B 1 271 ? 7.65792   23.00339  50.31443  1.000 30.42115 ?  251 PRO   B CB  1 
ATOM   4031 C CG  . PRO   B 1 271 ? 6.32463   22.46860  50.68397  1.000 33.11256 ?  251 PRO   B CG  1 
ATOM   4032 C CD  . PRO   B 1 271 ? 5.52974   22.40749  49.39582  1.000 31.01843 ?  251 PRO   B CD  1 
ATOM   4033 N N   . VAL   B 1 272 ? 9.93864   21.14201  49.20628  1.000 29.57933 ?  252 VAL   B N   1 
ATOM   4034 C CA  . VAL   B 1 272 ? 10.71750  19.92917  49.41370  1.000 33.63437 ?  252 VAL   B CA  1 
ATOM   4035 C C   . VAL   B 1 272 ? 10.26159  19.26511  50.70165  1.000 37.20563 ?  252 VAL   B C   1 
ATOM   4036 O O   . VAL   B 1 272 ? 10.24253  19.88747  51.77128  1.000 38.42471 ?  252 VAL   B O   1 
ATOM   4037 C CB  . VAL   B 1 272 ? 12.21945  20.24672  49.44422  1.000 34.90426 ?  252 VAL   B CB  1 
ATOM   4038 C CG1 . VAL   B 1 272 ? 13.02656  18.96663  49.60488  1.000 38.97973 ?  252 VAL   B CG1 1 
ATOM   4039 C CG2 . VAL   B 1 272 ? 12.63353  20.98304  48.17924  1.000 30.56511 ?  252 VAL   B CG2 1 
ATOM   4040 N N   . GLY   B 1 273 ? 9.88367   17.99447  50.60317  1.000 37.38908 ?  253 GLY   B N   1 
ATOM   4041 C CA  . GLY   B 1 273 ? 9.31294   17.27802  51.72070  1.000 34.07621 ?  253 GLY   B CA  1 
ATOM   4042 C C   . GLY   B 1 273 ? 7.80990   17.14302  51.68261  1.000 34.13634 ?  253 GLY   B C   1 
ATOM   4043 O O   . GLY   B 1 273 ? 7.24137   16.51028  52.57940  1.000 33.90173 ?  253 GLY   B O   1 
ATOM   4044 N N   . ARG   B 1 274 ? 7.15126   17.71543  50.67781  1.000 35.02679 ?  254 ARG   B N   1 
ATOM   4045 C CA  . ARG   B 1 274 ? 5.70455   17.60124  50.56617  1.000 35.19385 ?  254 ARG   B CA  1 
ATOM   4046 C C   . ARG   B 1 274 ? 5.30072   16.15087  50.33954  1.000 33.84390 ?  254 ARG   B C   1 
ATOM   4047 O O   . ARG   B 1 274 ? 5.84770   15.46670  49.46950  1.000 30.49109 ?  254 ARG   B O   1 
ATOM   4048 C CB  . ARG   B 1 274 ? 5.19291   18.47831  49.42218  1.000 34.98259 ?  254 ARG   B CB  1 
ATOM   4049 C CG  . ARG   B 1 274 ? 3.84838   18.04541  48.85679  1.000 39.83756 ?  254 ARG   B CG  1 
ATOM   4050 C CD  . ARG   B 1 274 ? 2.71580   18.39384  49.80603  1.000 31.69951 ?  254 ARG   B CD  1 
ATOM   4051 N NE  . ARG   B 1 274 ? 2.55586   19.83557  49.94813  1.000 38.42622 ?  254 ARG   B NE  1 
ATOM   4052 C CZ  . ARG   B 1 274 ? 2.68227   20.49332  51.09208  1.000 37.15635 ?  254 ARG   B CZ  1 
ATOM   4053 N NH1 . ARG   B 1 274 ? 2.97458   19.86743  52.22031  1.000 35.90151 ?  254 ARG   B NH1 1 
ATOM   4054 N NH2 . ARG   B 1 274 ? 2.51206   21.81223  51.10415  1.000 41.20131 ?  254 ARG   B NH2 1 
ATOM   4055 N N   . LEU   B 1 275 ? 4.34736   15.68087  51.13660  1.000 31.21470 ?  255 LEU   B N   1 
ATOM   4056 C CA  . LEU   B 1 275 ? 3.75589   14.36213  50.96007  1.000 34.52738 ?  255 LEU   B CA  1 
ATOM   4057 C C   . LEU   B 1 275 ? 2.42099   14.51468  50.24520  1.000 40.45939 ?  255 LEU   B C   1 
ATOM   4058 O O   . LEU   B 1 275 ? 1.53554   15.23222  50.72252  1.000 33.57804 ?  255 LEU   B O   1 
ATOM   4059 C CB  . LEU   B 1 275 ? 3.55997   13.65544  52.30091  1.000 30.21048 ?  255 LEU   B CB  1 
ATOM   4060 C CG  . LEU   B 1 275 ? 4.80678   13.38713  53.13907  1.000 32.33638 ?  255 LEU   B CG  1 
ATOM   4061 C CD1 . LEU   B 1 275 ? 4.42397   12.77592  54.47808  1.000 29.43447 ?  255 LEU   B CD1 1 
ATOM   4062 C CD2 . LEU   B 1 275 ? 5.76261   12.48122  52.38487  1.000 24.88845 ?  255 LEU   B CD2 1 
ATOM   4063 N N   . ARG   B 1 276 ? 2.28079   13.84605  49.10591  1.000 30.00379 ?  256 ARG   B N   1 
ATOM   4064 C CA  . ARG   B 1 276 ? 1.02214   13.80155  48.38220  1.000 37.01775 ?  256 ARG   B CA  1 
ATOM   4065 C C   . ARG   B 1 276 ? 0.68692   12.35137  48.06108  1.000 29.34349 ?  256 ARG   B C   1 
ATOM   4066 O O   . ARG   B 1 276 ? 1.48375   11.43826  48.29105  1.000 30.74940 ?  256 ARG   B O   1 
ATOM   4067 C CB  . ARG   B 1 276 ? 1.06535   14.65921  47.10825  1.000 31.25893 ?  256 ARG   B CB  1 
ATOM   4068 C CG  . ARG   B 1 276 ? 2.33752   14.56236  46.28794  1.000 29.98424 ?  256 ARG   B CG  1 
ATOM   4069 C CD  . ARG   B 1 276 ? 2.52135   15.82332  45.45421  1.000 23.27060 ?  256 ARG   B CD  1 
ATOM   4070 N NE  . ARG   B 1 276 ? 3.66426   15.73859  44.55321  1.000 28.09410 ?  256 ARG   B NE  1 
ATOM   4071 C CZ  . ARG   B 1 276 ? 3.63243   15.17256  43.35443  1.000 22.31329 ?  256 ARG   B CZ  1 
ATOM   4072 N NH1 . ARG   B 1 276 ? 2.52698   14.62386  42.87841  1.000 16.43695 ?  256 ARG   B NH1 1 
ATOM   4073 N NH2 . ARG   B 1 276 ? 4.73844   15.15453  42.61588  1.000 23.20385 ?  256 ARG   B NH2 1 
ATOM   4074 N N   . PHE   B 1 277 ? -0.51645  12.14428  47.53423  1.000 26.56935 ?  257 PHE   B N   1 
ATOM   4075 C CA  . PHE   B 1 277 ? -1.04838  10.80537  47.33730  1.000 23.66296 ?  257 PHE   B CA  1 
ATOM   4076 C C   . PHE   B 1 277 ? -1.88174  10.79085  46.06486  1.000 29.18758 ?  257 PHE   B C   1 
ATOM   4077 O O   . PHE   B 1 277 ? -2.69034  11.69368  45.83712  1.000 23.43963 ?  257 PHE   B O   1 
ATOM   4078 C CB  . PHE   B 1 277 ? -1.88895  10.37571  48.54593  1.000 28.50845 ?  257 PHE   B CB  1 
ATOM   4079 C CG  . PHE   B 1 277 ? -2.29342  8.93068   48.52752  1.000 32.21166 ?  257 PHE   B CG  1 
ATOM   4080 C CD1 . PHE   B 1 277 ? -3.43016  8.51788   47.85132  1.000 22.91037 ?  257 PHE   B CD1 1 
ATOM   4081 C CD2 . PHE   B 1 277 ? -1.53527  7.98444   49.19612  1.000 26.13602 ?  257 PHE   B CD2 1 
ATOM   4082 C CE1 . PHE   B 1 277 ? -3.79967  7.18979   47.84073  1.000 23.28088 ?  257 PHE   B CE1 1 
ATOM   4083 C CE2 . PHE   B 1 277 ? -1.89827  6.65585   49.18897  1.000 18.33991 ?  257 PHE   B CE2 1 
ATOM   4084 C CZ  . PHE   B 1 277 ? -3.03205  6.25673   48.51103  1.000 22.16055 ?  257 PHE   B CZ  1 
ATOM   4085 N N   . SER   B 1 278 ? -1.67840  9.76366   45.24059  1.000 25.09908 ?  258 SER   B N   1 
ATOM   4086 C CA  . SER   B 1 278 ? -2.36622  9.61784   43.95950  1.000 27.46856 ?  258 SER   B CA  1 
ATOM   4087 C C   . SER   B 1 278 ? -3.14033  8.30628   43.96593  1.000 23.63120 ?  258 SER   B C   1 
ATOM   4088 O O   . SER   B 1 278 ? -2.54118  7.22757   43.90499  1.000 22.38315 ?  258 SER   B O   1 
ATOM   4089 C CB  . SER   B 1 278 ? -1.37591  9.65883   42.79587  1.000 26.59921 ?  258 SER   B CB  1 
ATOM   4090 O OG  . SER   B 1 278 ? -1.99407  9.24947   41.58895  1.000 26.25318 ?  258 SER   B OG  1 
ATOM   4091 N N   . GLN   B 1 279 ? -4.47059  8.39968   44.03168  1.000 26.57346 ?  259 GLN   B N   1 
ATOM   4092 C CA  . GLN   B 1 279 ? -5.29696  7.19673   44.00642  1.000 26.07331 ?  259 GLN   B CA  1 
ATOM   4093 C C   . GLN   B 1 279 ? -5.38768  6.61422   42.60113  1.000 25.20179 ?  259 GLN   B C   1 
ATOM   4094 O O   . GLN   B 1 279 ? -5.37039  5.38978   42.42702  1.000 24.77208 ?  259 GLN   B O   1 
ATOM   4095 C CB  . GLN   B 1 279 ? -6.69998  7.50469   44.52923  1.000 22.19914 ?  259 GLN   B CB  1 
ATOM   4096 C CG  . GLN   B 1 279 ? -6.76450  8.20989   45.87092  1.000 23.61449 ?  259 GLN   B CG  1 
ATOM   4097 C CD  . GLN   B 1 279 ? -8.09628  8.90967   46.07989  1.000 23.87249 ?  259 GLN   B CD  1 
ATOM   4098 O OE1 . GLN   B 1 279 ? -8.64637  9.50951   45.15564  1.000 25.37486 ?  259 GLN   B OE1 1 
ATOM   4099 N NE2 . GLN   B 1 279 ? -8.62689  8.82520   47.29410  1.000 23.19027 ?  259 GLN   B NE2 1 
ATOM   4100 N N   . ALA   B 1 280 ? -5.48694  7.47654   41.58701  1.000 25.22213 ?  260 ALA   B N   1 
ATOM   4101 C CA  . ALA   B 1 280 ? -5.79604  7.03242   40.23325  1.000 25.54516 ?  260 ALA   B CA  1 
ATOM   4102 C C   . ALA   B 1 280 ? -4.61714  6.37580   39.52849  1.000 17.22854 ?  260 ALA   B C   1 
ATOM   4103 O O   . ALA   B 1 280 ? -4.82932  5.64659   38.55387  1.000 19.20396 ?  260 ALA   B O   1 
ATOM   4104 C CB  . ALA   B 1 280 ? -6.30023  8.20963   39.39513  1.000 18.54765 ?  260 ALA   B CB  1 
ATOM   4105 N N   . THR   B 1 281 ? -3.38725  6.61556   39.98271  1.000 24.30622 ?  261 THR   B N   1 
ATOM   4106 C CA  . THR   B 1 281 ? -2.21440  5.98412   39.39402  1.000 25.68299 ?  261 THR   B CA  1 
ATOM   4107 C C   . THR   B 1 281 ? -1.68407  4.83132   40.24123  1.000 26.19244 ?  261 THR   B C   1 
ATOM   4108 O O   . THR   B 1 281 ? -0.55715  4.37631   40.01959  1.000 26.00553 ?  261 THR   B O   1 
ATOM   4109 C CB  . THR   B 1 281 ? -1.11087  7.01650   39.15076  1.000 24.88607 ?  261 THR   B CB  1 
ATOM   4110 O OG1 . THR   B 1 281 ? -0.67805  7.56839   40.40014  1.000 25.34153 ?  261 THR   B OG1 1 
ATOM   4111 C CG2 . THR   B 1 281 ? -1.61351  8.13095   38.24328  1.000 25.39369 ?  261 THR   B CG2 1 
ATOM   4112 N N   . GLY   B 1 282 ? -2.46915  4.35032   41.20361  1.000 25.17754 ?  262 GLY   B N   1 
ATOM   4113 C CA  . GLY   B 1 282 ? -2.11120  3.14082   41.91788  1.000 19.54333 ?  262 GLY   B CA  1 
ATOM   4114 C C   . GLY   B 1 282 ? -2.03321  3.26487   43.42564  1.000 21.32622 ?  262 GLY   B C   1 
ATOM   4115 O O   . GLY   B 1 282 ? -1.35660  2.46070   44.07409  1.000 21.89866 ?  262 GLY   B O   1 
ATOM   4116 N N   . ASN   B 1 283 ? -2.72066  4.25514   43.99415  1.000 21.81966 ?  263 ASN   B N   1 
ATOM   4117 C CA  . ASN   B 1 283 ? -2.74067  4.48917   45.43915  1.000 16.32456 ?  263 ASN   B CA  1 
ATOM   4118 C C   . ASN   B 1 283 ? -1.31906  4.60490   45.99193  1.000 20.19445 ?  263 ASN   B C   1 
ATOM   4119 O O   . ASN   B 1 283 ? -0.88160  3.83240   46.84619  1.000 22.76484 ?  263 ASN   B O   1 
ATOM   4120 C CB  . ASN   B 1 283 ? -3.52773  3.39139   46.15964  1.000 22.29969 ?  263 ASN   B CB  1 
ATOM   4121 C CG  . ASN   B 1 283 ? -4.97137  3.77920   46.41629  1.000 18.44092 ?  263 ASN   B CG  1 
ATOM   4122 O OD1 . ASN   B 1 283 ? -5.30441  4.30099   47.47971  1.000 26.13485 ?  263 ASN   B OD1 1 
ATOM   4123 N ND2 . ASN   B 1 283 ? -5.83782  3.52104   45.44320  1.000 19.19951 ?  263 ASN   B ND2 1 
ATOM   4124 N N   . LYS   B 1 284 ? -0.60116  5.60252   45.48678  1.000 19.45551 ?  264 LYS   B N   1 
ATOM   4125 C CA  . LYS   B 1 284 ? 0.81864   5.77169   45.75630  1.000 24.25517 ?  264 LYS   B CA  1 
ATOM   4126 C C   . LYS   B 1 284 ? 1.05650   6.93977   46.70434  1.000 25.55309 ?  264 LYS   B C   1 
ATOM   4127 O O   . LYS   B 1 284 ? 0.46486   8.01309   46.54686  1.000 26.26671 ?  264 LYS   B O   1 
ATOM   4128 C CB  . LYS   B 1 284 ? 1.59472   6.00586   44.45662  1.000 21.49733 ?  264 LYS   B CB  1 
ATOM   4129 C CG  . LYS   B 1 284 ? 1.24023   5.05156   43.33439  1.000 23.43795 ?  264 LYS   B CG  1 
ATOM   4130 C CD  . LYS   B 1 284 ? 2.38083   4.94472   42.33663  1.000 27.33357 ?  264 LYS   B CD  1 
ATOM   4131 C CE  . LYS   B 1 284 ? 2.28448   6.02774   41.27464  1.000 26.10653 ?  264 LYS   B CE  1 
ATOM   4132 N NZ  . LYS   B 1 284 ? 2.68857   5.53669   39.92629  1.000 30.45975 ?  264 LYS   B NZ  1 
ATOM   4133 N N   . VAL   B 1 285 ? 1.92897   6.72464   47.68469  1.000 29.30009 ?  265 VAL   B N   1 
ATOM   4134 C CA  . VAL   B 1 285 ? 2.42439   7.80816   48.52805  1.000 29.74824 ?  265 VAL   B CA  1 
ATOM   4135 C C   . VAL   B 1 285 ? 3.58939   8.47357   47.80540  1.000 24.16762 ?  265 VAL   B C   1 
ATOM   4136 O O   . VAL   B 1 285 ? 4.57912   7.81657   47.46641  1.000 28.26524 ?  265 VAL   B O   1 
ATOM   4137 C CB  . VAL   B 1 285 ? 2.85106   7.28864   49.90793  1.000 21.73512 ?  265 VAL   B CB  1 
ATOM   4138 C CG1 . VAL   B 1 285 ? 3.75217   8.30130   50.60118  1.000 22.11460 ?  265 VAL   B CG1 1 
ATOM   4139 C CG2 . VAL   B 1 285 ? 1.62791   6.98364   50.75636  1.000 22.11371 ?  265 VAL   B CG2 1 
ATOM   4140 N N   . ILE   B 1 286 ? 3.47643   9.77732   47.56865  1.000 26.71279 ?  266 ILE   B N   1 
ATOM   4141 C CA  . ILE   B 1 286 ? 4.41586   10.51452  46.73185  1.000 31.28809 ?  266 ILE   B CA  1 
ATOM   4142 C C   . ILE   B 1 286 ? 5.22640   11.45135  47.61368  1.000 28.73097 ?  266 ILE   B C   1 
ATOM   4143 O O   . ILE   B 1 286 ? 4.66953   12.14846  48.46983  1.000 33.38732 ?  266 ILE   B O   1 
ATOM   4144 C CB  . ILE   B 1 286 ? 3.68543   11.29192  45.62423  1.000 28.74380 ?  266 ILE   B CB  1 
ATOM   4145 C CG1 . ILE   B 1 286 ? 2.93432   10.32534  44.70861  1.000 28.69247 ?  266 ILE   B CG1 1 
ATOM   4146 C CG2 . ILE   B 1 286 ? 4.66766   12.12181  44.81751  1.000 30.14599 ?  266 ILE   B CG2 1 
ATOM   4147 C CD1 . ILE   B 1 286 ? 1.98691   11.00970  43.75828  1.000 23.38399 ?  266 ILE   B CD1 1 
ATOM   4148 N N   . VAL   B 1 287 ? 6.53795   11.46891  47.40446  1.000 26.87804 ?  267 VAL   B N   1 
ATOM   4149 C CA  . VAL   B 1 287 ? 7.44366   12.32219  48.16102  1.000 29.47694 ?  267 VAL   B CA  1 
ATOM   4150 C C   . VAL   B 1 287 ? 8.08835   13.29971  47.19168  1.000 34.43621 ?  267 VAL   B C   1 
ATOM   4151 O O   . VAL   B 1 287 ? 8.78578   12.88745  46.25740  1.000 31.05635 ?  267 VAL   B O   1 
ATOM   4152 C CB  . VAL   B 1 287 ? 8.50729   11.50360  48.90735  1.000 33.17993 ?  267 VAL   B CB  1 
ATOM   4153 C CG1 . VAL   B 1 287 ? 9.50545   12.42420  49.58819  1.000 31.50421 ?  267 VAL   B CG1 1 
ATOM   4154 C CG2 . VAL   B 1 287 ? 7.84121   10.58971  49.92162  1.000 21.43575 ?  267 VAL   B CG2 1 
ATOM   4155 N N   . GLN   B 1 288 ? 7.85533   14.58832  47.40899  1.000 30.76139 ?  268 GLN   B N   1 
ATOM   4156 C CA  . GLN   B 1 288 ? 8.50499   15.62436  46.62301  1.000 35.59487 ?  268 GLN   B CA  1 
ATOM   4157 C C   . GLN   B 1 288 ? 9.84720   15.97009  47.25424  1.000 31.31661 ?  268 GLN   B C   1 
ATOM   4158 O O   . GLN   B 1 288 ? 9.92345   16.24797  48.46133  1.000 38.09984 ?  268 GLN   B O   1 
ATOM   4159 C CB  . GLN   B 1 288 ? 7.61965   16.86634  46.52830  1.000 32.58772 ?  268 GLN   B CB  1 
ATOM   4160 C CG  . GLN   B 1 288 ? 7.97931   17.81450  45.38992  1.000 36.98558 ?  268 GLN   B CG  1 
ATOM   4161 C CD  . GLN   B 1 288 ? 7.67586   17.23295  44.01922  1.000 28.71234 ?  268 GLN   B CD  1 
ATOM   4162 O OE1 . GLN   B 1 288 ? 6.67686   16.53659  43.83366  1.000 34.54410 ?  268 GLN   B OE1 1 
ATOM   4163 N NE2 . GLN   B 1 288 ? 8.53230   17.52952  43.04771  1.000 36.84428 ?  268 GLN   B NE2 1 
ATOM   4164 N N   . TYR   B 1 289 ? 10.90450  15.93220  46.43142  1.000 32.96042 ?  269 TYR   B N   1 
ATOM   4165 C CA  . TYR   B 1 289 ? 12.22503  16.34520  46.88120  1.000 38.39347 ?  269 TYR   B CA  1 
ATOM   4166 C C   . TYR   B 1 289 ? 12.93252  17.33916  45.95476  1.000 30.02053 ?  269 TYR   B C   1 
ATOM   4167 O O   . TYR   B 1 289 ? 13.91188  17.94064  46.39565  1.000 39.95474 ?  269 TYR   B O   1 
ATOM   4168 C CB  . TYR   B 1 289 ? 13.11925  15.10807  47.10025  1.000 29.31772 ?  269 TYR   B CB  1 
ATOM   4169 C CG  . TYR   B 1 289 ? 13.60154  14.43903  45.83459  1.000 27.13044 ?  269 TYR   B CG  1 
ATOM   4170 C CD1 . TYR   B 1 289 ? 14.81528  14.79384  45.26308  1.000 27.26881 ?  269 TYR   B CD1 1 
ATOM   4171 C CD2 . TYR   B 1 289 ? 12.82887  13.47869  45.19040  1.000 32.50326 ?  269 TYR   B CD2 1 
ATOM   4172 C CE1 . TYR   B 1 289 ? 15.25629  14.20447  44.09477  1.000 33.58594 ?  269 TYR   B CE1 1 
ATOM   4173 C CE2 . TYR   B 1 289 ? 13.26207  12.88533  44.01966  1.000 25.04677 ?  269 TYR   B CE2 1 
ATOM   4174 C CZ  . TYR   B 1 289 ? 14.47313  13.25041  43.47720  1.000 27.64174 ?  269 TYR   B CZ  1 
ATOM   4175 O OH  . TYR   B 1 289 ? 14.90591  12.66116  42.31240  1.000 34.96064 ?  269 TYR   B OH  1 
ATOM   4176 N N   . GLY   B 1 290 ? 12.46901  17.57023  44.71873  1.000 31.26013 ?  270 GLY   B N   1 
ATOM   4177 C CA  . GLY   B 1 290 ? 13.12112  18.46367  43.76905  1.000 34.64171 ?  270 GLY   B CA  1 
ATOM   4178 C C   . GLY   B 1 290 ? 12.09344  19.34897  43.07293  1.000 43.23984 ?  270 GLY   B C   1 
ATOM   4179 O O   . GLY   B 1 290 ? 10.88132  19.24071  43.33197  1.000 36.43172 ?  270 GLY   B O   1 
ATOM   4180 N N   . PRO   B 1 291 ? 12.53232  20.22237  42.16072  1.000 50.64403 ?  271 PRO   B N   1 
ATOM   4181 C CA  . PRO   B 1 291 ? 11.56108  21.05901  41.45044  1.000 45.27820 ?  271 PRO   B CA  1 
ATOM   4182 C C   . PRO   B 1 291 ? 10.73586  20.24178  40.46501  1.000 41.67530 ?  271 PRO   B C   1 
ATOM   4183 O O   . PRO   B 1 291 ? 10.90342  19.03659  40.28350  1.000 46.10125 ?  271 PRO   B O   1 
ATOM   4184 C CB  . PRO   B 1 291 ? 12.45767  22.08891  40.74251  1.000 43.95705 ?  271 PRO   B CB  1 
ATOM   4185 C CG  . PRO   B 1 291 ? 13.81325  21.94866  41.49845  1.000 45.68935 ?  271 PRO   B CG  1 
ATOM   4186 C CD  . PRO   B 1 291 ? 13.86942  20.46752  41.59478  1.000 50.01022 ?  271 PRO   B CD  1 
ATOM   4187 N N   . THR   B 1 292 ? 9.80519   20.94083  39.83601  1.000 43.40595 ?  272 THR   B N   1 
ATOM   4188 C CA  . THR   B 1 292 ? 9.01891   20.46747  38.70946  1.000 50.29197 ?  272 THR   B CA  1 
ATOM   4189 C C   . THR   B 1 292 ? 8.23296   21.64913  38.16634  1.000 45.13642 ?  272 THR   B C   1 
ATOM   4190 O O   . THR   B 1 292 ? 7.90943   22.58823  38.89977  1.000 41.22324 ?  272 THR   B O   1 
ATOM   4191 C CB  . THR   B 1 292 ? 8.05641   19.33108  39.08165  1.000 40.91287 ?  272 THR   B CB  1 
ATOM   4192 O OG1 . THR   B 1 292 ? 7.55595   18.74044  37.87703  1.000 44.54473 ?  272 THR   B OG1 1 
ATOM   4193 C CG2 . THR   B 1 292 ? 6.88213   19.85144  39.88844  1.000 44.29645 ?  272 THR   B CG2 1 
ATOM   4194 N N   . THR   B 1 293 ? 7.98664   21.61783  36.86583  1.000 49.51657 ?  273 THR   B N   1 
ATOM   4195 C CA  . THR   B 1 293 ? 7.17160   22.61945  36.21222  1.000 41.40046 ?  273 THR   B CA  1 
ATOM   4196 C C   . THR   B 1 293 ? 5.72589   22.18402  36.07655  1.000 44.74265 ?  273 THR   B C   1 
ATOM   4197 O O   . THR   B 1 293 ? 4.95395   22.88613  35.42517  1.000 49.73382 ?  273 THR   B O   1 
ATOM   4198 C CB  . THR   B 1 293 ? 7.74155   22.93262  34.82855  1.000 42.94279 ?  273 THR   B CB  1 
ATOM   4199 O OG1 . THR   B 1 293 ? 7.59621   21.79208  33.96985  1.000 52.95651 ?  273 THR   B OG1 1 
ATOM   4200 C CG2 . THR   B 1 293 ? 9.20712   23.32432  34.90974  1.000 49.04859 ?  273 THR   B CG2 1 
ATOM   4201 N N   . GLU   B 1 294 ? 5.34424   21.05404  36.67305  1.000 44.74762 ?  274 GLU   B N   1 
ATOM   4202 C CA  . GLU   B 1 294 ? 3.97242   20.57086  36.57370  1.000 43.35852 ?  274 GLU   B CA  1 
ATOM   4203 C C   . GLU   B 1 294 ? 3.01113   21.56163  37.21178  1.000 39.73339 ?  274 GLU   B C   1 
ATOM   4204 O O   . GLU   B 1 294 ? 3.14115   21.89030  38.39496  1.000 40.63993 ?  274 GLU   B O   1 
ATOM   4205 C CB  . GLU   B 1 294 ? 3.83848   19.21224  37.25519  1.000 44.62347 ?  274 GLU   B CB  1 
ATOM   4206 C CG  . GLU   B 1 294 ? 4.63961   18.09182  36.62896  1.000 45.40140 ?  274 GLU   B CG  1 
ATOM   4207 C CD  . GLU   B 1 294 ? 5.00961   17.02312  37.64198  1.000 49.00795 ?  274 GLU   B CD  1 
ATOM   4208 O OE1 . GLU   B 1 294 ? 4.12448   16.22181  38.00594  1.000 44.47374 ?  274 GLU   B OE1 1 
ATOM   4209 O OE2 . GLU   B 1 294 ? 6.17842   16.97822  38.07496  1.000 44.71429 ?  274 GLU   B OE2 1 
ATOM   4210 N N   . THR   B 1 295 ? 2.03156   22.01980  36.43383  1.000 42.56395 ?  275 THR   B N   1 
ATOM   4211 C CA  . THR   B 1 295 ? 0.96854   22.87079  36.94586  1.000 45.02689 ?  275 THR   B CA  1 
ATOM   4212 C C   . THR   B 1 295 ? -0.26370  22.06829  37.34874  1.000 49.69134 ?  275 THR   B C   1 
ATOM   4213 O O   . THR   B 1 295 ? -1.35785  22.63038  37.45807  1.000 56.71889 ?  275 THR   B O   1 
ATOM   4214 C CB  . THR   B 1 295 ? 0.59503   23.92971  35.90843  1.000 44.76880 ?  275 THR   B CB  1 
ATOM   4215 O OG1 . THR   B 1 295 ? -0.01527  23.29993  34.77607  1.000 43.62775 ?  275 THR   B OG1 1 
ATOM   4216 C CG2 . THR   B 1 295 ? 1.83703   24.68215  35.44648  1.000 42.12975 ?  275 THR   B CG2 1 
ATOM   4217 N N   . LEU   B 1 296 ? -0.10614  20.77130  37.57921  1.000 46.15248 ?  276 LEU   B N   1 
ATOM   4218 C CA  . LEU   B 1 296 ? -1.23720  19.88153  37.77553  1.000 50.16222 ?  276 LEU   B CA  1 
ATOM   4219 C C   . LEU   B 1 296 ? -1.60562  19.77985  39.25445  1.000 53.93123 ?  276 LEU   B C   1 
ATOM   4220 O O   . LEU   B 1 296 ? -0.87692  20.22972  40.14163  1.000 45.44630 ?  276 LEU   B O   1 
ATOM   4221 C CB  . LEU   B 1 296 ? -0.92154  18.49985  37.20772  1.000 53.32491 ?  276 LEU   B CB  1 
ATOM   4222 C CG  . LEU   B 1 296 ? -2.09060  17.64237  36.72882  1.000 51.77846 ?  276 LEU   B CG  1 
ATOM   4223 C CD1 . LEU   B 1 296 ? -3.23497  18.49806  36.22114  1.000 53.87812 ?  276 LEU   B CD1 1 
ATOM   4224 C CD2 . LEU   B 1 296 ? -1.60359  16.70590  35.64880  1.000 49.03389 ?  276 LEU   B CD2 1 
ATOM   4225 N N   . SER   B 1 297 ? -2.76016  19.16933  39.51052  1.000 50.28422 ?  277 SER   B N   1 
ATOM   4226 C CA  . SER   B 1 297 ? -3.30343  19.05664  40.85575  1.000 51.10333 ?  277 SER   B CA  1 
ATOM   4227 C C   . SER   B 1 297 ? -2.88539  17.74033  41.49580  1.000 38.22937 ?  277 SER   B C   1 
ATOM   4228 O O   . SER   B 1 297 ? -2.79020  16.70903  40.82421  1.000 45.22371 ?  277 SER   B O   1 
ATOM   4229 C CB  . SER   B 1 297 ? -4.82976  19.15932  40.82602  1.000 55.69727 ?  277 SER   B CB  1 
ATOM   4230 O OG  . SER   B 1 297 ? -5.39752  18.13192  40.03040  1.000 52.11308 ?  277 SER   B OG  1 
ATOM   4231 N N   . SER   B 1 298 ? -2.63774  17.78396  42.80567  1.000 43.54240 ?  278 SER   B N   1 
ATOM   4232 C CA  . SER   B 1 298 ? -2.28570  16.59607  43.55439  1.000 32.67245 ?  278 SER   B CA  1 
ATOM   4233 C C   . SER   B 1 298 ? -2.74020  16.79083  44.99528  1.000 36.58245 ?  278 SER   B C   1 
ATOM   4234 O O   . SER   B 1 298 ? -2.47331  17.85492  45.57755  1.000 34.86677 ?  278 SER   B O   1 
ATOM   4235 C CB  . SER   B 1 298 ? -0.78618  16.30505  43.50955  1.000 33.00529 ?  278 SER   B CB  1 
ATOM   4236 O OG  . SER   B 1 298 ? -0.45123  15.25178  44.39354  1.000 30.27744 ?  278 SER   B OG  1 
ATOM   4237 N N   . PRO   B 1 299 ? -3.41824  15.80554  45.58272  1.000 32.65828 ?  279 PRO   B N   1 
ATOM   4238 C CA  . PRO   B 1 299 ? -3.94719  15.97366  46.94236  1.000 28.40906 ?  279 PRO   B CA  1 
ATOM   4239 C C   . PRO   B 1 299 ? -2.83143  16.15725  47.95892  1.000 36.97992 ?  279 PRO   B C   1 
ATOM   4240 O O   . PRO   B 1 299 ? -1.82527  15.44651  47.94192  1.000 35.77741 ?  279 PRO   B O   1 
ATOM   4241 C CB  . PRO   B 1 299 ? -4.71395  14.66944  47.18962  1.000 27.68138 ?  279 PRO   B CB  1 
ATOM   4242 C CG  . PRO   B 1 299 ? -4.95428  14.09319  45.83431  1.000 32.67804 ?  279 PRO   B CG  1 
ATOM   4243 C CD  . PRO   B 1 299 ? -3.80652  14.51973  44.98517  1.000 27.68907 ?  279 PRO   B CD  1 
ATOM   4244 N N   . VAL   B 1 300 ? -3.02374  17.11551  48.85825  1.000 34.48998 ?  280 VAL   B N   1 
ATOM   4245 C CA  . VAL   B 1 300 ? -2.03915  17.39081  49.89822  1.000 38.66093 ?  280 VAL   B CA  1 
ATOM   4246 C C   . VAL   B 1 300 ? -2.25137  16.40373  51.04058  1.000 36.16272 ?  280 VAL   B C   1 
ATOM   4247 O O   . VAL   B 1 300 ? -3.33432  16.34392  51.63276  1.000 35.57263 ?  280 VAL   B O   1 
ATOM   4248 C CB  . VAL   B 1 300 ? -2.14276  18.84331  50.38527  1.000 39.19559 ?  280 VAL   B CB  1 
ATOM   4249 C CG1 . VAL   B 1 300 ? -1.64819  18.96973  51.81015  1.000 38.71426 ?  280 VAL   B CG1 1 
ATOM   4250 C CG2 . VAL   B 1 300 ? -1.36117  19.76512  49.46645  1.000 39.73280 ?  280 VAL   B CG2 1 
ATOM   4251 N N   . LEU   B 1 301 ? -1.22263  15.61530  51.33848  1.000 36.14444 ?  281 LEU   B N   1 
ATOM   4252 C CA  . LEU   B 1 301 ? -1.25791  14.63984  52.42114  1.000 28.96022 ?  281 LEU   B CA  1 
ATOM   4253 C C   . LEU   B 1 301 ? -0.44084  15.06197  53.63045  1.000 28.27613 ?  281 LEU   B C   1 
ATOM   4254 O O   . LEU   B 1 301 ? -0.85965  14.82550  54.76696  1.000 30.06671 ?  281 LEU   B O   1 
ATOM   4255 C CB  . LEU   B 1 301 ? -0.75464  13.27786  51.92347  1.000 28.66372 ?  281 LEU   B CB  1 
ATOM   4256 C CG  . LEU   B 1 301 ? -0.70989  12.14285  52.95046  1.000 30.96286 ?  281 LEU   B CG  1 
ATOM   4257 C CD1 . LEU   B 1 301 ? -2.11480  11.74765  53.36944  1.000 24.84089 ?  281 LEU   B CD1 1 
ATOM   4258 C CD2 . LEU   B 1 301 ? 0.04284   10.94619  52.39453  1.000 22.19713 ?  281 LEU   B CD2 1 
ATOM   4259 N N   . GLY   B 1 302 ? 0.70981   15.69160  53.41898  1.000 33.65028 ?  282 GLY   B N   1 
ATOM   4260 C CA  . GLY   B 1 302 ? 1.51889   16.13416  54.53697  1.000 32.49023 ?  282 GLY   B CA  1 
ATOM   4261 C C   . GLY   B 1 302 ? 2.83181   16.72463  54.06540  1.000 33.18195 ?  282 GLY   B C   1 
ATOM   4262 O O   . GLY   B 1 302 ? 2.97131   17.12730  52.90876  1.000 36.14115 ?  282 GLY   B O   1 
ATOM   4263 N N   . LYS   B 1 303 ? 3.78922   16.76591  54.98831  1.000 37.38309 ?  283 LYS   B N   1 
ATOM   4264 C CA  . LYS   B 1 303 ? 5.08543   17.36707  54.71935  1.000 36.73176 ?  283 LYS   B CA  1 
ATOM   4265 C C   . LYS   B 1 303 ? 6.12984   16.75216  55.63798  1.000 39.07261 ?  283 LYS   B C   1 
ATOM   4266 O O   . LYS   B 1 303 ? 5.87977   16.56646  56.83156  1.000 35.12970 ?  283 LYS   B O   1 
ATOM   4267 C CB  . LYS   B 1 303 ? 5.04388   18.88749  54.92024  1.000 34.62754 ?  283 LYS   B CB  1 
ATOM   4268 C CG  . LYS   B 1 303 ? 6.11122   19.64919  54.15256  1.000 36.69357 ?  283 LYS   B CG  1 
ATOM   4269 C CD  . LYS   B 1 303 ? 6.17774   21.10171  54.59810  1.000 38.68689 ?  283 LYS   B CD  1 
ATOM   4270 C CE  . LYS   B 1 303 ? 6.84493   21.23140  55.95830  1.000 44.23874 ?  283 LYS   B CE  1 
ATOM   4271 N NZ  . LYS   B 1 303 ? 8.33015   21.22482  55.85963  1.000 45.77616 ?  283 LYS   B NZ  1 
ATOM   4272 N N   . VAL   B 1 304 ? 7.29478   16.43663  55.07041  1.000 37.01888 ?  284 VAL   B N   1 
ATOM   4273 C CA  . VAL   B 1 304 ? 8.46736   16.13914  55.88329  1.000 38.21866 ?  284 VAL   B CA  1 
ATOM   4274 C C   . VAL   B 1 304 ? 8.87282   17.39296  56.64410  1.000 37.23665 ?  284 VAL   B C   1 
ATOM   4275 O O   . VAL   B 1 304 ? 8.90543   18.49507  56.08064  1.000 36.42620 ?  284 VAL   B O   1 
ATOM   4276 C CB  . VAL   B 1 304 ? 9.61800   15.61834  55.00958  1.000 39.28695 ?  284 VAL   B CB  1 
ATOM   4277 C CG1 . VAL   B 1 304 ? 10.76212  15.14872  55.88166  1.000 41.91320 ?  284 VAL   B CG1 1 
ATOM   4278 C CG2 . VAL   B 1 304 ? 9.13866   14.47259  54.13143  1.000 38.35422 ?  284 VAL   B CG2 1 
ATOM   4279 N N   . VAL   B 1 305 ? 9.18733   17.22883  57.93316  1.000 39.43426 ?  285 VAL   B N   1 
ATOM   4280 C CA  . VAL   B 1 305 ? 9.46179   18.38300  58.77988  1.000 45.54990 ?  285 VAL   B CA  1 
ATOM   4281 C C   . VAL   B 1 305 ? 10.64259  19.18377  58.22911  1.000 45.40503 ?  285 VAL   B C   1 
ATOM   4282 O O   . VAL   B 1 305 ? 11.49670  18.67392  57.49171  1.000 44.03955 ?  285 VAL   B O   1 
ATOM   4283 C CB  . VAL   B 1 305 ? 9.71030   17.95781  60.23579  1.000 38.61690 ?  285 VAL   B CB  1 
ATOM   4284 C CG1 . VAL   B 1 305 ? 8.60312   17.02550  60.70496  1.000 37.19321 ?  285 VAL   B CG1 1 
ATOM   4285 C CG2 . VAL   B 1 305 ? 11.06718  17.29013  60.37596  1.000 41.19035 ?  285 VAL   B CG2 1 
ATOM   4286 N N   . ASP   B 1 306 ? 10.67296  20.46899  58.59125  1.000 45.51896 ?  286 ASP   B N   1 
ATOM   4287 C CA  . ASP   B 1 306 ? 11.61719  21.39744  57.97735  1.000 48.08277 ?  286 ASP   B CA  1 
ATOM   4288 C C   . ASP   B 1 306 ? 13.06082  21.00595  58.26729  1.000 42.48490 ?  286 ASP   B C   1 
ATOM   4289 O O   . ASP   B 1 306 ? 13.92376  21.09719  57.38651  1.000 41.37889 ?  286 ASP   B O   1 
ATOM   4290 C CB  . ASP   B 1 306 ? 11.33832  22.81992  58.46305  1.000 55.08677 ?  286 ASP   B CB  1 
ATOM   4291 C CG  . ASP   B 1 306 ? 10.17700  23.46818  57.73297  1.000 57.00612 ?  286 ASP   B CG  1 
ATOM   4292 O OD1 . ASP   B 1 306 ? 10.18770  23.47880  56.48374  1.000 48.50784 ?  286 ASP   B OD1 1 
ATOM   4293 O OD2 . ASP   B 1 306 ? 9.25315   23.96777  58.40957  1.000 64.48867 ?  286 ASP   B OD2 1 
ATOM   4294 N N   . SER   B 1 307 ? 13.34335  20.55915  59.49078  1.000 42.62128 ?  287 SER   B N   1 
ATOM   4295 C CA  . SER   B 1 307 ? 14.71240  20.22925  59.87080  1.000 38.51098 ?  287 SER   B CA  1 
ATOM   4296 C C   . SER   B 1 307 ? 15.19993  18.91429  59.27740  1.000 43.14162 ?  287 SER   B C   1 
ATOM   4297 O O   . SER   B 1 307 ? 16.34049  18.52250  59.55084  1.000 42.07509 ?  287 SER   B O   1 
ATOM   4298 C CB  . SER   B 1 307 ? 14.83265  20.18636  61.39483  1.000 40.22698 ?  287 SER   B CB  1 
ATOM   4299 O OG  . SER   B 1 307 ? 13.76059  19.45771  61.96524  1.000 38.51052 ?  287 SER   B OG  1 
ATOM   4300 N N   . HIS   B 1 308 ? 14.38182  18.22946  58.47651  1.000 45.20430 ?  288 HIS   B N   1 
ATOM   4301 C CA  . HIS   B 1 308 ? 14.76869  16.96468  57.86618  1.000 44.31414 ?  288 HIS   B CA  1 
ATOM   4302 C C   . HIS   B 1 308 ? 14.71925  16.98184  56.34341  1.000 41.85488 ?  288 HIS   B C   1 
ATOM   4303 O O   . HIS   B 1 308 ? 15.09459  15.98315  55.71926  1.000 41.25324 ?  288 HIS   B O   1 
ATOM   4304 C CB  . HIS   B 1 308 ? 13.87983  15.82621  58.38802  1.000 39.14763 ?  288 HIS   B CB  1 
ATOM   4305 C CG  . HIS   B 1 308 ? 14.22463  15.37339  59.77308  1.000 41.00051 ?  288 HIS   B CG  1 
ATOM   4306 N ND1 . HIS   B 1 308 ? 13.52703  14.38111  60.42789  1.000 38.70865 ?  288 HIS   B ND1 1 
ATOM   4307 C CD2 . HIS   B 1 308 ? 15.19113  15.78048  60.62910  1.000 37.58000 ?  288 HIS   B CD2 1 
ATOM   4308 C CE1 . HIS   B 1 308 ? 14.05135  14.19389  61.62592  1.000 48.52945 ?  288 HIS   B CE1 1 
ATOM   4309 N NE2 . HIS   B 1 308 ? 15.06230  15.03101  61.77310  1.000 42.78344 ?  288 HIS   B NE2 1 
ATOM   4310 N N   . ALA   B 1 309 ? 14.27705  18.08356  55.72922  1.000 38.90876 ?  289 ALA   B N   1 
ATOM   4311 C CA  . ALA   B 1 309 ? 14.12352  18.14138  54.27877  1.000 43.24587 ?  289 ALA   B CA  1 
ATOM   4312 C C   . ALA   B 1 309 ? 15.44425  17.95896  53.54229  1.000 41.28545 ?  289 ALA   B C   1 
ATOM   4313 O O   . ALA   B 1 309 ? 15.44171  17.51926  52.38700  1.000 38.17185 ?  289 ALA   B O   1 
ATOM   4314 C CB  . ALA   B 1 309 ? 13.47143  19.46946  53.87735  1.000 39.00123 ?  289 ALA   B CB  1 
ATOM   4315 N N   . ASP   B 1 310 ? 16.57048  18.27092  54.18487  1.000 41.02597 ?  290 ASP   B N   1 
ATOM   4316 C CA  . ASP   B 1 310 ? 17.86879  18.09605  53.54734  1.000 42.90554 ?  290 ASP   B CA  1 
ATOM   4317 C C   . ASP   B 1 310 ? 18.23673  16.63222  53.35366  1.000 40.09997 ?  290 ASP   B C   1 
ATOM   4318 O O   . ASP   B 1 310 ? 19.17211  16.34064  52.60021  1.000 41.26798 ?  290 ASP   B O   1 
ATOM   4319 C CB  . ASP   B 1 310 ? 18.96005  18.81164  54.35422  1.000 41.59744 ?  290 ASP   B CB  1 
ATOM   4320 C CG  . ASP   B 1 310 ? 18.98763  18.39342  55.82199  1.000 46.13350 ?  290 ASP   B CG  1 
ATOM   4321 O OD1 . ASP   B 1 310 ? 19.65136  19.08622  56.62427  1.000 55.94275 ?  290 ASP   B OD1 1 
ATOM   4322 O OD2 . ASP   B 1 310 ? 18.34142  17.39064  56.18553  1.000 48.67619 ?  290 ASP   B OD2 1 
ATOM   4323 N N   . ARG   B 1 311 ? 17.52397  15.71520  54.00063  1.000 44.99982 ?  291 ARG   B N   1 
ATOM   4324 C CA  . ARG   B 1 311 ? 17.81791  14.29173  53.92933  1.000 41.24936 ?  291 ARG   B CA  1 
ATOM   4325 C C   . ARG   B 1 311 ? 17.14068  13.59926  52.75552  1.000 38.46878 ?  291 ARG   B C   1 
ATOM   4326 O O   . ARG   B 1 311 ? 17.27587  12.38011  52.61791  1.000 37.82714 ?  291 ARG   B O   1 
ATOM   4327 C CB  . ARG   B 1 311 ? 17.39200  13.59504  55.22659  1.000 38.11685 ?  291 ARG   B CB  1 
ATOM   4328 C CG  . ARG   B 1 311 ? 18.13959  14.03354  56.47407  1.000 41.68706 ?  291 ARG   B CG  1 
ATOM   4329 C CD  . ARG   B 1 311 ? 17.21751  13.97578  57.68556  1.000 42.41600 ?  291 ARG   B CD  1 
ATOM   4330 N NE  . ARG   B 1 311 ? 17.91768  14.21459  58.94209  1.000 44.47068 ?  291 ARG   B NE  1 
ATOM   4331 C CZ  . ARG   B 1 311 ? 17.61939  13.61478  60.08692  1.000 41.83536 ?  291 ARG   B CZ  1 
ATOM   4332 N NH1 . ARG   B 1 311 ? 16.63855  12.73049  60.16865  1.000 33.95376 ?  291 ARG   B NH1 1 
ATOM   4333 N NH2 . ARG   B 1 311 ? 18.32472  13.90651  61.17621  1.000 44.00913 ?  291 ARG   B NH2 1 
ATOM   4334 N N   . LEU   B 1 312 ? 16.41813  14.33246  51.91158  1.000 38.36605 ?  292 LEU   B N   1 
ATOM   4335 C CA  . LEU   B 1 312 ? 15.65624  13.70317  50.84063  1.000 32.98255 ?  292 LEU   B CA  1 
ATOM   4336 C C   . LEU   B 1 312 ? 16.40186  13.67374  49.51623  1.000 35.00108 ?  292 LEU   B C   1 
ATOM   4337 O O   . LEU   B 1 312 ? 16.11223  12.81621  48.67374  1.000 30.04449 ?  292 LEU   B O   1 
ATOM   4338 C CB  . LEU   B 1 312 ? 14.31861  14.42115  50.65416  1.000 36.38673 ?  292 LEU   B CB  1 
ATOM   4339 C CG  . LEU   B 1 312 ? 13.41985  14.47819  51.88857  1.000 35.91761 ?  292 LEU   B CG  1 
ATOM   4340 C CD1 . LEU   B 1 312 ? 12.32319  15.49304  51.67261  1.000 33.08301 ?  292 LEU   B CD1 1 
ATOM   4341 C CD2 . LEU   B 1 312 ? 12.83201  13.10864  52.19407  1.000 36.65180 ?  292 LEU   B CD2 1 
ATOM   4342 N N   . ALA   B 1 313 ? 17.35445  14.58614  49.31401  1.000 33.65653 ?  293 ALA   B N   1 
ATOM   4343 C CA  . ALA   B 1 313 ? 18.06857  14.64424  48.04272  1.000 32.49939 ?  293 ALA   B CA  1 
ATOM   4344 C C   . ALA   B 1 313 ? 18.86384  13.36710  47.79956  1.000 38.12670 ?  293 ALA   B C   1 
ATOM   4345 O O   . ALA   B 1 313 ? 18.84432  12.80954  46.69598  1.000 39.08410 ?  293 ALA   B O   1 
ATOM   4346 C CB  . ALA   B 1 313 ? 18.98510  15.86699  48.01337  1.000 31.22866 ?  293 ALA   B CB  1 
ATOM   4347 N N   . GLU   B 1 314 ? 19.56928  12.88471  48.82552  1.000 38.76261 ?  294 GLU   B N   1 
ATOM   4348 C CA  . GLU   B 1 314 ? 20.34624  11.65784  48.67500  1.000 39.96853 ?  294 GLU   B CA  1 
ATOM   4349 C C   . GLU   B 1 314 ? 19.43838  10.46077  48.41661  1.000 33.38344 ?  294 GLU   B C   1 
ATOM   4350 O O   . GLU   B 1 314 ? 19.79797  9.55007   47.66087  1.000 34.89520 ?  294 GLU   B O   1 
ATOM   4351 C CB  . GLU   B 1 314 ? 21.21906  11.41180  49.91323  1.000 34.54793 ?  294 GLU   B CB  1 
ATOM   4352 C CG  . GLU   B 1 314 ? 21.87717  12.64513  50.55133  1.000 45.06798 ?  294 GLU   B CG  1 
ATOM   4353 C CD  . GLU   B 1 314 ? 20.90091  13.56019  51.27720  1.000 49.92590 ?  294 GLU   B CD  1 
ATOM   4354 O OE1 . GLU   B 1 314 ? 19.70630  13.21211  51.36574  1.000 52.62382 ?  294 GLU   B OE1 1 
ATOM   4355 O OE2 . GLU   B 1 314 ? 21.33065  14.63169  51.74818  1.000 47.52500 ?  294 GLU   B OE2 1 
ATOM   4356 N N   . VAL   B 1 315 ? 18.25429  10.44424  49.03135  1.000 30.27047 ?  295 VAL   B N   1 
ATOM   4357 C CA  . VAL   B 1 315 ? 17.31013  9.35643   48.78466  1.000 33.91466 ?  295 VAL   B CA  1 
ATOM   4358 C C   . VAL   B 1 315 ? 16.78859  9.41998   47.35435  1.000 31.34069 ?  295 VAL   B C   1 
ATOM   4359 O O   . VAL   B 1 315 ? 16.79197  8.41766   46.62976  1.000 25.40027 ?  295 VAL   B O   1 
ATOM   4360 C CB  . VAL   B 1 315 ? 16.15717  9.39642   49.80321  1.000 31.43508 ?  295 VAL   B CB  1 
ATOM   4361 C CG1 . VAL   B 1 315 ? 15.26547  8.17218   49.64687  1.000 29.10268 ?  295 VAL   B CG1 1 
ATOM   4362 C CG2 . VAL   B 1 315 ? 16.70506  9.48813   51.21743  1.000 30.83020 ?  295 VAL   B CG2 1 
ATOM   4363 N N   . GLY   B 1 316 ? 16.34116  10.60306  46.92579  1.000 28.61496 ?  296 GLY   B N   1 
ATOM   4364 C CA  . GLY   B 1 316 ? 15.84686  10.75123  45.56586  1.000 31.55535 ?  296 GLY   B CA  1 
ATOM   4365 C C   . GLY   B 1 316 ? 16.89255  10.41196  44.52119  1.000 32.61023 ?  296 GLY   B C   1 
ATOM   4366 O O   . GLY   B 1 316 ? 16.57124  9.86736   43.46196  1.000 31.10151 ?  296 GLY   B O   1 
ATOM   4367 N N   . LYS   B 1 317 ? 18.15852  10.73038  44.80441  1.000 32.36766 ?  297 LYS   B N   1 
ATOM   4368 C CA  . LYS   B 1 317 ? 19.24440  10.33084  43.91450  1.000 33.13657 ?  297 LYS   B CA  1 
ATOM   4369 C C   . LYS   B 1 317 ? 19.41290  8.81547   43.91392  1.000 34.12578 ?  297 LYS   B C   1 
ATOM   4370 O O   . LYS   B 1 317 ? 19.51114  8.19125   42.85079  1.000 37.66077 ?  297 LYS   B O   1 
ATOM   4371 C CB  . LYS   B 1 317 ? 20.54313  11.02968  44.32977  1.000 36.73696 ?  297 LYS   B CB  1 
ATOM   4372 C CG  . LYS   B 1 317 ? 21.81314  10.51497  43.65227  1.000 41.07906 ?  297 LYS   B CG  1 
ATOM   4373 C CD  . LYS   B 1 317 ? 21.66358  10.38684  42.14200  1.000 49.43128 ?  297 LYS   B CD  1 
ATOM   4374 C CE  . LYS   B 1 317 ? 22.38387  9.14605   41.63705  1.000 48.49117 ?  297 LYS   B CE  1 
ATOM   4375 N NZ  . LYS   B 1 317 ? 21.76887  8.60035   40.39807  1.000 45.30064 ?  297 LYS   B NZ  1 
ATOM   4376 N N   . ALA   B 1 318 ? 19.43658  8.20467   45.10075  1.000 34.65915 ?  298 ALA   B N   1 
ATOM   4377 C CA  . ALA   B 1 318 ? 19.57100  6.75400   45.18241  1.000 28.44368 ?  298 ALA   B CA  1 
ATOM   4378 C C   . ALA   B 1 318 ? 18.35496  6.05182   44.59162  1.000 31.94317 ?  298 ALA   B C   1 
ATOM   4379 O O   . ALA   B 1 318 ? 18.48806  5.02000   43.92238  1.000 27.85231 ?  298 ALA   B O   1 
ATOM   4380 C CB  . ALA   B 1 318 ? 19.78372  6.32970   46.63450  1.000 24.98162 ?  298 ALA   B CB  1 
ATOM   4381 N N   . VAL   B 1 319 ? 17.16021  6.59853   44.82665  1.000 30.21383 ?  299 VAL   B N   1 
ATOM   4382 C CA  . VAL   B 1 319 ? 15.94468  5.98885   44.29732  1.000 26.99077 ?  299 VAL   B CA  1 
ATOM   4383 C C   . VAL   B 1 319 ? 15.92672  6.06178   42.77580  1.000 27.02848 ?  299 VAL   B C   1 
ATOM   4384 O O   . VAL   B 1 319 ? 15.53128  5.10285   42.10114  1.000 24.72045 ?  299 VAL   B O   1 
ATOM   4385 C CB  . VAL   B 1 319 ? 14.70310  6.65496   44.91694  1.000 26.73953 ?  299 VAL   B CB  1 
ATOM   4386 C CG1 . VAL   B 1 319 ? 13.45787  6.31715   44.11750  1.000 27.00216 ?  299 VAL   B CG1 1 
ATOM   4387 C CG2 . VAL   B 1 319 ? 14.54211  6.21767   46.36094  1.000 26.63394 ?  299 VAL   B CG2 1 
ATOM   4388 N N   . TRP   B 1 320 ? 16.35687  7.19265   42.20905  1.000 32.92480 ?  300 TRP   B N   1 
ATOM   4389 C CA  . TRP   B 1 320 ? 16.43932  7.29325   40.75589  1.000 33.20451 ?  300 TRP   B CA  1 
ATOM   4390 C C   . TRP   B 1 320 ? 17.40170  6.25873   40.18994  1.000 30.97492 ?  300 TRP   B C   1 
ATOM   4391 O O   . TRP   B 1 320 ? 17.11461  5.63243   39.16422  1.000 29.13703 ?  300 TRP   B O   1 
ATOM   4392 C CB  . TRP   B 1 320 ? 16.86548  8.70009   40.33749  1.000 36.06735 ?  300 TRP   B CB  1 
ATOM   4393 C CG  . TRP   B 1 320 ? 17.22421  8.79133   38.88238  1.000 42.35119 ?  300 TRP   B CG  1 
ATOM   4394 C CD1 . TRP   B 1 320 ? 18.47898  8.84143   38.34630  1.000 39.82774 ?  300 TRP   B CD1 1 
ATOM   4395 C CD2 . TRP   B 1 320 ? 16.31449  8.82337   37.77603  1.000 39.36998 ?  300 TRP   B CD2 1 
ATOM   4396 N NE1 . TRP   B 1 320 ? 18.40565  8.91235   36.97577  1.000 48.37675 ?  300 TRP   B NE1 1 
ATOM   4397 C CE2 . TRP   B 1 320 ? 17.08783  8.89930   36.60087  1.000 42.98153 ?  300 TRP   B CE2 1 
ATOM   4398 C CE3 . TRP   B 1 320 ? 14.92079  8.79823   37.66566  1.000 51.75900 ?  300 TRP   B CE3 1 
ATOM   4399 C CZ2 . TRP   B 1 320 ? 16.51389  8.95932   35.33300  1.000 48.20684 ?  300 TRP   B CZ2 1 
ATOM   4400 C CZ3 . TRP   B 1 320 ? 14.35321  8.84997   36.40502  1.000 40.51469 ?  300 TRP   B CZ3 1 
ATOM   4401 C CH2 . TRP   B 1 320 ? 15.14849  8.92890   35.25589  1.000 44.49700 ?  300 TRP   B CH2 1 
ATOM   4402 N N   . GLU   B 1 321 ? 18.54806  6.06293   40.84830  1.000 29.58568 ?  301 GLU   B N   1 
ATOM   4403 C CA  . GLU   B 1 321 ? 19.50336  5.05651   40.39373  1.000 37.14373 ?  301 GLU   B CA  1 
ATOM   4404 C C   . GLU   B 1 321 ? 18.86324  3.67584   40.33250  1.000 34.55114 ?  301 GLU   B C   1 
ATOM   4405 O O   . GLU   B 1 321 ? 19.11501  2.90571   39.39792  1.000 37.43411 ?  301 GLU   B O   1 
ATOM   4406 C CB  . GLU   B 1 321 ? 20.72416  5.03946   41.31607  1.000 41.13688 ?  301 GLU   B CB  1 
ATOM   4407 C CG  . GLU   B 1 321 ? 21.79169  4.03010   40.92053  1.000 43.64049 ?  301 GLU   B CG  1 
ATOM   4408 C CD  . GLU   B 1 321 ? 22.62821  4.49156   39.74364  1.000 50.99890 ?  301 GLU   B CD  1 
ATOM   4409 O OE1 . GLU   B 1 321 ? 23.25915  3.63432   39.09057  1.000 49.59882 ?  301 GLU   B OE1 1 
ATOM   4410 O OE2 . GLU   B 1 321 ? 22.66031  5.71080   39.47444  1.000 56.60691 ?  301 GLU   B OE2 1 
ATOM   4411 N N   . SER   B 1 322 ? 18.02451  3.35161   41.31733  1.000 33.10987 ?  302 SER   B N   1 
ATOM   4412 C CA  . SER   B 1 322 ? 17.35818  2.05479   41.34470  1.000 31.34048 ?  302 SER   B CA  1 
ATOM   4413 C C   . SER   B 1 322 ? 16.39871  1.90547   40.16943  1.000 30.28922 ?  302 SER   B C   1 
ATOM   4414 O O   . SER   B 1 322 ? 16.57901  1.04029   39.30586  1.000 27.90678 ?  302 SER   B O   1 
ATOM   4415 C CB  . SER   B 1 322 ? 16.62014  1.88557   42.67409  1.000 24.25236 ?  302 SER   B CB  1 
ATOM   4416 O OG  . SER   B 1 322 ? 15.92258  0.65197   42.71974  1.000 26.28746 ?  302 SER   B OG  1 
ATOM   4417 N N   . THR   B 1 323 ? 15.37540  2.76066   40.11495  1.000 28.28576 ?  303 THR   B N   1 
ATOM   4418 C CA  . THR   B 1 323 ? 14.33344  2.62359   39.10168  1.000 29.88306 ?  303 THR   B CA  1 
ATOM   4419 C C   . THR   B 1 323 ? 14.88706  2.75271   37.68642  1.000 30.71119 ?  303 THR   B C   1 
ATOM   4420 O O   . THR   B 1 323 ? 14.40430  2.08063   36.76708  1.000 29.81304 ?  303 THR   B O   1 
ATOM   4421 C CB  . THR   B 1 323 ? 13.24490  3.67174   39.33982  1.000 28.08553 ?  303 THR   B CB  1 
ATOM   4422 O OG1 . THR   B 1 323 ? 12.74738  3.54733   40.67742  1.000 31.03634 ?  303 THR   B OG1 1 
ATOM   4423 C CG2 . THR   B 1 323 ? 12.09218  3.48602   38.36518  1.000 27.59182 ?  303 THR   B CG2 1 
ATOM   4424 N N   . PHE   B 1 324 ? 15.90575  3.58891   37.49243  1.000 29.47440 ?  304 PHE   B N   1 
ATOM   4425 C CA  . PHE   B 1 324 ? 16.35831  3.93499   36.14978  1.000 29.36952 ?  304 PHE   B CA  1 
ATOM   4426 C C   . PHE   B 1 324 ? 17.37874  2.94849   35.59085  1.000 32.96998 ?  304 PHE   B C   1 
ATOM   4427 O O   . PHE   B 1 324 ? 17.31081  2.60404   34.40702  1.000 34.22094 ?  304 PHE   B O   1 
ATOM   4428 C CB  . PHE   B 1 324 ? 16.92888  5.35733   36.15531  1.000 36.01403 ?  304 PHE   B CB  1 
ATOM   4429 C CG  . PHE   B 1 324 ? 17.63258  5.75200   34.88795  1.000 42.75733 ?  304 PHE   B CG  1 
ATOM   4430 C CD1 . PHE   B 1 324 ? 16.90755  6.12634   33.76870  1.000 46.23077 ?  304 PHE   B CD1 1 
ATOM   4431 C CD2 . PHE   B 1 324 ? 19.01702  5.79886   34.82988  1.000 45.12527 ?  304 PHE   B CD2 1 
ATOM   4432 C CE1 . PHE   B 1 324 ? 17.54814  6.51663   32.60793  1.000 51.22043 ?  304 PHE   B CE1 1 
ATOM   4433 C CE2 . PHE   B 1 324 ? 19.66469  6.18365   33.66829  1.000 48.55357 ?  304 PHE   B CE2 1 
ATOM   4434 C CZ  . PHE   B 1 324 ? 18.92848  6.54373   32.55681  1.000 44.95738 ?  304 PHE   B CZ  1 
ATOM   4435 N N   . SER   B 1 325 ? 18.31510  2.46601   36.40873  1.000 39.26450 ?  305 SER   B N   1 
ATOM   4436 C CA  . SER   B 1 325 ? 19.37949  1.62242   35.87411  1.000 39.76340 ?  305 SER   B CA  1 
ATOM   4437 C C   . SER   B 1 325 ? 19.67069  0.39231   36.72781  1.000 35.57334 ?  305 SER   B C   1 
ATOM   4438 O O   . SER   B 1 325 ? 19.62630  -0.73716  36.22926  1.000 40.88089 ?  305 SER   B O   1 
ATOM   4439 C CB  . SER   B 1 325 ? 20.66213  2.44096   35.70549  1.000 37.01482 ?  305 SER   B CB  1 
ATOM   4440 O OG  . SER   B 1 325 ? 20.85391  3.32246   36.79784  1.000 42.81794 ?  305 SER   B OG  1 
ATOM   4441 N N   . SER   B 1 326 ? 19.97885  0.59596   38.00965  1.000 35.91982 ?  306 SER   B N   1 
ATOM   4442 C CA  . SER   B 1 326 ? 20.53087  -0.48699  38.81784  1.000 31.04998 ?  306 SER   B CA  1 
ATOM   4443 C C   . SER   B 1 326 ? 19.47907  -1.50291  39.24799  1.000 34.38837 ?  306 SER   B C   1 
ATOM   4444 O O   . SER   B 1 326 ? 19.78969  -2.69514  39.35235  1.000 38.61717 ?  306 SER   B O   1 
ATOM   4445 C CB  . SER   B 1 326 ? 21.23475  0.08645   40.04826  1.000 31.40274 ?  306 SER   B CB  1 
ATOM   4446 O OG  . SER   B 1 326 ? 20.31532  0.32048   41.10046  1.000 34.21877 ?  306 SER   B OG  1 
ATOM   4447 N N   . LYS   B 1 327 ? 18.25016  -1.05637  39.51071  1.000 34.99391 ?  307 LYS   B N   1 
ATOM   4448 C CA  . LYS   B 1 327 ? 17.15205  -1.90093  39.98712  1.000 30.61334 ?  307 LYS   B CA  1 
ATOM   4449 C C   . LYS   B 1 327 ? 17.43921  -2.52019  41.35168  1.000 31.30403 ?  307 LYS   B C   1 
ATOM   4450 O O   . LYS   B 1 327 ? 16.81542  -3.51849  41.72693  1.000 27.26157 ?  307 LYS   B O   1 
ATOM   4451 C CB  . LYS   B 1 327 ? 16.79626  -2.99691  38.97327  1.000 31.49196 ?  307 LYS   B CB  1 
ATOM   4452 C CG  . LYS   B 1 327 ? 15.72997  -2.59286  37.96456  1.000 29.44196 ?  307 LYS   B CG  1 
ATOM   4453 C CD  . LYS   B 1 327 ? 16.22913  -1.51107  37.02035  1.000 31.77125 ?  307 LYS   B CD  1 
ATOM   4454 C CE  . LYS   B 1 327 ? 15.37080  -1.43063  35.76767  1.000 30.57713 ?  307 LYS   B CE  1 
ATOM   4455 N NZ  . LYS   B 1 327 ? 14.07465  -0.74254  36.02119  1.000 24.32378 ?  307 LYS   B NZ  1 
ATOM   4456 N N   . GLU   B 1 328 ? 18.36859  -1.94568  42.10696  1.000 29.49408 ?  308 GLU   B N   1 
ATOM   4457 C CA  . GLU   B 1 328 ? 18.61215  -2.39684  43.47103  1.000 31.66190 ?  308 GLU   B CA  1 
ATOM   4458 C C   . GLU   B 1 328 ? 17.51148  -1.86513  44.38068  1.000 28.63496 ?  308 GLU   B C   1 
ATOM   4459 O O   . GLU   B 1 328 ? 17.29470  -0.64935  44.42499  1.000 28.08664 ?  308 GLU   B O   1 
ATOM   4460 C CB  . GLU   B 1 328 ? 19.97702  -1.92972  43.95741  1.000 35.66285 ?  308 GLU   B CB  1 
ATOM   4461 C CG  . GLU   B 1 328 ? 21.14316  -2.50726  43.17067  1.000 40.47627 ?  308 GLU   B CG  1 
ATOM   4462 C CD  . GLU   B 1 328 ? 21.69257  -3.77710  43.79188  1.000 49.40193 ?  308 GLU   B CD  1 
ATOM   4463 O OE1 . GLU   B 1 328 ? 22.39645  -3.68226  44.81940  1.000 55.96389 ?  308 GLU   B OE1 1 
ATOM   4464 O OE2 . GLU   B 1 328 ? 21.42008  -4.87084  43.25282  1.000 51.06339 ?  308 GLU   B OE2 1 
ATOM   4465 N N   . PRO   B 1 329 ? 16.80677  -2.72306  45.11661  1.000 26.86607 ?  309 PRO   B N   1 
ATOM   4466 C CA  . PRO   B 1 329 ? 15.60156  -2.27420  45.82478  1.000 29.26328 ?  309 PRO   B CA  1 
ATOM   4467 C C   . PRO   B 1 329 ? 15.90513  -1.24773  46.90754  1.000 32.68839 ?  309 PRO   B C   1 
ATOM   4468 O O   . PRO   B 1 329 ? 16.87217  -1.37288  47.66231  1.000 35.31124 ?  309 PRO   B O   1 
ATOM   4469 C CB  . PRO   B 1 329 ? 15.04648  -3.57012  46.42773  1.000 30.35339 ?  309 PRO   B CB  1 
ATOM   4470 C CG  . PRO   B 1 329 ? 15.61845  -4.65885  45.57405  1.000 33.25911 ?  309 PRO   B CG  1 
ATOM   4471 C CD  . PRO   B 1 329 ? 16.99322  -4.17909  45.21879  1.000 31.01156 ?  309 PRO   B CD  1 
ATOM   4472 N N   . VAL   B 1 330 ? 15.06213  -0.22000  46.96655  1.000 26.97003 ?  310 VAL   B N   1 
ATOM   4473 C CA  . VAL   B 1 330 ? 15.02454  0.73164   48.07122  1.000 28.21620 ?  310 VAL   B CA  1 
ATOM   4474 C C   . VAL   B 1 330 ? 13.67495  0.56840   48.75423  1.000 29.93928 ?  310 VAL   B C   1 
ATOM   4475 O O   . VAL   B 1 330 ? 12.62653  0.75390   48.12386  1.000 30.82896 ?  310 VAL   B O   1 
ATOM   4476 C CB  . VAL   B 1 330 ? 15.23222  2.17725   47.59429  1.000 28.51334 ?  310 VAL   B CB  1 
ATOM   4477 C CG1 . VAL   B 1 330 ? 15.17222  3.13812   48.77458  1.000 26.05768 ?  310 VAL   B CG1 1 
ATOM   4478 C CG2 . VAL   B 1 330 ? 16.55666  2.31099   46.85810  1.000 24.36680 ?  310 VAL   B CG2 1 
ATOM   4479 N N   . TRP   B 1 331 ? 13.69617  0.21484   50.03437  1.000 27.94117 ?  311 TRP   B N   1 
ATOM   4480 C CA  . TRP   B 1 331 ? 12.48329  -0.10329  50.77432  1.000 24.08759 ?  311 TRP   B CA  1 
ATOM   4481 C C   . TRP   B 1 331 ? 12.10302  1.06124   51.67734  1.000 29.10639 ?  311 TRP   B C   1 
ATOM   4482 O O   . TRP   B 1 331 ? 12.93007  1.54766   52.45519  1.000 26.46866 ?  311 TRP   B O   1 
ATOM   4483 C CB  . TRP   B 1 331 ? 12.67197  -1.37789  51.59747  1.000 28.24680 ?  311 TRP   B CB  1 
ATOM   4484 C CG  . TRP   B 1 331 ? 12.91411  -2.59096  50.75286  1.000 29.95028 ?  311 TRP   B CG  1 
ATOM   4485 C CD1 . TRP   B 1 331 ? 14.12129  -3.14167  50.43286  1.000 24.63572 ?  311 TRP   B CD1 1 
ATOM   4486 C CD2 . TRP   B 1 331 ? 11.92205  -3.39550  50.10593  1.000 27.76262 ?  311 TRP   B CD2 1 
ATOM   4487 N NE1 . TRP   B 1 331 ? 13.94127  -4.24467  49.63319  1.000 31.11895 ?  311 TRP   B NE1 1 
ATOM   4488 C CE2 . TRP   B 1 331 ? 12.59976  -4.42140  49.41734  1.000 33.04659 ?  311 TRP   B CE2 1 
ATOM   4489 C CE3 . TRP   B 1 331 ? 10.52610  -3.35004  50.04515  1.000 28.87487 ?  311 TRP   B CE3 1 
ATOM   4490 C CZ2 . TRP   B 1 331 ? 11.92878  -5.39325  48.67748  1.000 29.71894 ?  311 TRP   B CZ2 1 
ATOM   4491 C CZ3 . TRP   B 1 331 ? 9.86210   -4.31504  49.31061  1.000 30.60259 ?  311 TRP   B CZ3 1 
ATOM   4492 C CH2 . TRP   B 1 331 ? 10.56336  -5.32297  48.63673  1.000 29.57202 ?  311 TRP   B CH2 1 
ATOM   4493 N N   . LEU   B 1 332 ? 10.85373  1.50145   51.57268  1.000 25.62717 ?  312 LEU   B N   1 
ATOM   4494 C CA  . LEU   B 1 332 ? 10.33781  2.60684   52.36630  1.000 25.77678 ?  312 LEU   B CA  1 
ATOM   4495 C C   . LEU   B 1 332 ? 9.40477   2.07458   53.44285  1.000 27.16950 ?  312 LEU   B C   1 
ATOM   4496 O O   . LEU   B 1 332 ? 8.44897   1.35304   53.14010  1.000 29.71204 ?  312 LEU   B O   1 
ATOM   4497 C CB  . LEU   B 1 332 ? 9.59692   3.61674   51.48920  1.000 27.41558 ?  312 LEU   B CB  1 
ATOM   4498 C CG  . LEU   B 1 332 ? 8.65699   4.54591   52.25987  1.000 29.84475 ?  312 LEU   B CG  1 
ATOM   4499 C CD1 . LEU   B 1 332 ? 9.41160   5.74497   52.81832  1.000 27.54825 ?  312 LEU   B CD1 1 
ATOM   4500 C CD2 . LEU   B 1 332 ? 7.49927   4.98945   51.37931  1.000 33.64588 ?  312 LEU   B CD2 1 
ATOM   4501 N N   . THR   B 1 333 ? 9.68149   2.43487   54.69184  1.000 23.92900 ?  313 THR   B N   1 
ATOM   4502 C CA  . THR   B 1 333 ? 8.81293   2.12026   55.81714  1.000 27.91825 ?  313 THR   B CA  1 
ATOM   4503 C C   . THR   B 1 333 ? 8.18529   3.40520   56.33570  1.000 29.43049 ?  313 THR   B C   1 
ATOM   4504 O O   . THR   B 1 333 ? 8.89708   4.35978   56.66284  1.000 32.45953 ?  313 THR   B O   1 
ATOM   4505 C CB  . THR   B 1 333 ? 9.58300   1.42593   56.94303  1.000 33.66709 ?  313 THR   B CB  1 
ATOM   4506 O OG1 . THR   B 1 333 ? 10.13889  0.19646   56.46019  1.000 27.67184 ?  313 THR   B OG1 1 
ATOM   4507 C CG2 . THR   B 1 333 ? 8.65794   1.13709   58.11827  1.000 28.89382 ?  313 THR   B CG2 1 
ATOM   4508 N N   . VAL   B 1 334 ? 6.85848   3.43092   56.40193  1.000 27.36169 ?  314 VAL   B N   1 
ATOM   4509 C CA  . VAL   B 1 334 ? 6.11690   4.55155   56.96384  1.000 29.31896 ?  314 VAL   B CA  1 
ATOM   4510 C C   . VAL   B 1 334 ? 5.41651   4.06047   58.22037  1.000 33.95518 ?  314 VAL   B C   1 
ATOM   4511 O O   . VAL   B 1 334 ? 4.67939   3.06749   58.18065  1.000 26.43813 ?  314 VAL   B O   1 
ATOM   4512 C CB  . VAL   B 1 334 ? 5.10988   5.13294   55.95737  1.000 30.86540 ?  314 VAL   B CB  1 
ATOM   4513 C CG1 . VAL   B 1 334 ? 4.37671   6.31836   56.57037  1.000 29.06117 ?  314 VAL   B CG1 1 
ATOM   4514 C CG2 . VAL   B 1 334 ? 5.81714   5.54298   54.67638  1.000 27.03944 ?  314 VAL   B CG2 1 
ATOM   4515 N N   . GLU   B 1 335 ? 5.65532   4.74803   59.33397  1.000 29.08739 ?  315 GLU   B N   1 
ATOM   4516 C CA  . GLU   B 1 335 ? 5.12502   4.34209   60.62509  1.000 35.95741 ?  315 GLU   B CA  1 
ATOM   4517 C C   . GLU   B 1 335 ? 4.67213   5.57129   61.39608  1.000 35.54615 ?  315 GLU   B C   1 
ATOM   4518 O O   . GLU   B 1 335 ? 5.20223   6.66951   61.21019  1.000 37.45407 ?  315 GLU   B O   1 
ATOM   4519 C CB  . GLU   B 1 335 ? 6.17017   3.57721   61.44859  1.000 36.22595 ?  315 GLU   B CB  1 
ATOM   4520 C CG  . GLU   B 1 335 ? 7.53310   4.25363   61.48490  1.000 39.15089 ?  315 GLU   B CG  1 
ATOM   4521 C CD  . GLU   B 1 335 ? 8.64419   3.31208   61.90448  1.000 35.30970 ?  315 GLU   B CD  1 
ATOM   4522 O OE1 . GLU   B 1 335 ? 8.78520   3.06398   63.11998  1.000 40.24702 ?  315 GLU   B OE1 1 
ATOM   4523 O OE2 . GLU   B 1 335 ? 9.37880   2.82293   61.02057  1.000 40.15933 ?  315 GLU   B OE2 1 
ATOM   4524 N N   . ARG   B 1 336 ? 3.68639   5.37475   62.26659  1.000 33.78243 ?  316 ARG   B N   1 
ATOM   4525 C CA  . ARG   B 1 336 ? 3.27055   6.43818   63.16488  1.000 42.72863 ?  316 ARG   B CA  1 
ATOM   4526 C C   . ARG   B 1 336 ? 4.36003   6.70894   64.19924  1.000 45.59598 ?  316 ARG   B C   1 
ATOM   4527 O O   . ARG   B 1 336 ? 5.26202   5.89628   64.42120  1.000 41.85430 ?  316 ARG   B O   1 
ATOM   4528 C CB  . ARG   B 1 336 ? 1.95967   6.07400   63.86204  1.000 42.65682 ?  316 ARG   B CB  1 
ATOM   4529 C CG  . ARG   B 1 336 ? 0.93761   7.19992   63.89777  1.000 45.22130 ?  316 ARG   B CG  1 
ATOM   4530 C CD  . ARG   B 1 336 ? -0.41781  6.69734   64.37008  1.000 47.32914 ?  316 ARG   B CD  1 
ATOM   4531 N NE  . ARG   B 1 336 ? -1.32784  7.79112   64.68871  1.000 41.56525 ?  316 ARG   B NE  1 
ATOM   4532 C CZ  . ARG   B 1 336 ? -2.60237  7.83561   64.32543  1.000 50.86986 ?  316 ARG   B CZ  1 
ATOM   4533 N NH1 . ARG   B 1 336 ? -3.15650  6.85866   63.62606  1.000 50.63779 ?  316 ARG   B NH1 1 
ATOM   4534 N NH2 . ARG   B 1 336 ? -3.34000  8.88631   64.67337  1.000 57.72836 ?  316 ARG   B NH2 1 
ATOM   4535 N N   . LEU   B 1 337 ? 4.26889   7.87122   64.83544  1.000 47.39424 ?  317 LEU   B N   1 
ATOM   4536 C CA  . LEU   B 1 337 ? 5.26041   8.26609   65.82895  1.000 50.83784 ?  317 LEU   B CA  1 
ATOM   4537 C C   . LEU   B 1 337 ? 4.63819   8.38609   67.21657  1.000 50.91329 ?  317 LEU   B C   1 
ATOM   4538 O O   . LEU   B 1 337 ? 3.47083   8.04964   67.41597  1.000 48.67378 ?  317 LEU   B O   1 
ATOM   4539 C CB  . LEU   B 1 337 ? 5.91930   9.58867   65.43007  1.000 43.22456 ?  317 LEU   B CB  1 
ATOM   4540 C CG  . LEU   B 1 337 ? 7.16814   9.49311   64.54880  1.000 45.22199 ?  317 LEU   B CG  1 
ATOM   4541 C CD1 . LEU   B 1 337 ? 7.97287   10.78266  64.61417  1.000 44.77226 ?  317 LEU   B CD1 1 
ATOM   4542 C CD2 . LEU   B 1 337 ? 8.02901   8.29985   64.94185  1.000 45.97135 ?  317 LEU   B CD2 1 
HETATM 4543 C C01 . A1L46 C 2 .   ? -3.59970  -4.94313  23.41127  1.000 26.56928 ?  401 A1L46 A C01 1 
HETATM 4544 C C02 . A1L46 C 2 .   ? -4.79750  -5.65412  23.53456  1.000 26.59981 ?  401 A1L46 A C02 1 
HETATM 4545 C C03 . A1L46 C 2 .   ? -5.04934  -6.74650  22.71319  1.000 21.14340 ?  401 A1L46 A C03 1 
HETATM 4546 C C04 . A1L46 C 2 .   ? -4.10064  -7.11012  21.78282  1.000 21.28314 ?  401 A1L46 A C04 1 
HETATM 4547 C C05 . A1L46 C 2 .   ? -2.92887  -6.41643  21.66185  1.000 24.85915 ?  401 A1L46 A C05 1 
HETATM 4548 C C06 . A1L46 C 2 .   ? -2.65248  -5.32786  22.46437  1.000 27.41363 ?  401 A1L46 A C06 1 
HETATM 4549 C C07 . A1L46 C 2 .   ? -2.93137  -8.09937  20.15747  1.000 25.31257 ?  401 A1L46 A C07 1 
HETATM 4550 C C08 . A1L46 C 2 .   ? -2.17335  -7.06194  20.60270  1.000 25.04713 ?  401 A1L46 A C08 1 
HETATM 4551 C C09 . A1L46 C 2 .   ? -2.50353  -9.01836  19.05637  1.000 26.68154 ?  401 A1L46 A C09 1 
HETATM 4552 C C10 . A1L46 C 2 .   ? -0.70007  -7.37011  18.66492  1.000 23.27298 ?  401 A1L46 A C10 1 
HETATM 4553 C C11 . A1L46 C 2 .   ? -0.83620  -6.72884  20.05327  1.000 28.05140 ?  401 A1L46 A C11 1 
HETATM 4554 C C12 . A1L46 C 2 .   ? 0.71637   -7.23650  18.18601  1.000 26.14875 ?  401 A1L46 A C12 1 
HETATM 4555 C C13 . A1L46 C 2 .   ? -3.34501  -8.73016  17.81151  1.000 31.20591 ?  401 A1L46 A C13 1 
HETATM 4556 C C14 . A1L46 C 2 .   ? -2.69885  -10.48651 19.44706  1.000 27.46022 ?  401 A1L46 A C14 1 
HETATM 4557 C C15 . A1L46 C 2 .   ? -2.46575  -10.73274 20.93885  1.000 22.46514 ?  401 A1L46 A C15 1 
HETATM 4558 C C16 . A1L46 C 2 .   ? -0.99518  -11.03187 21.21223  1.000 28.26848 ?  401 A1L46 A C16 1 
HETATM 4559 N N01 . A1L46 C 2 .   ? -4.15081  -8.14960  20.87467  1.000 25.74947 ?  401 A1L46 A N01 1 
HETATM 4560 N N02 . A1L46 C 2 .   ? -1.05664  -8.81371  18.73937  1.000 26.65807 ?  401 A1L46 A N02 1 
HETATM 4561 O O01 . A1L46 C 2 .   ? 1.43812   -8.26149  18.06539  1.000 28.47574 -1 401 A1L46 A O01 1 
HETATM 4562 O O02 . A1L46 C 2 .   ? 1.18516   -6.10188  17.90304  1.000 22.32013 ?  401 A1L46 A O02 1 
HETATM 4563 O O03 . A1L46 C 2 .   ? -4.54432  -9.11141  17.75289  1.000 35.86544 ?  401 A1L46 A O03 1 
HETATM 4564 O O04 . A1L46 C 2 .   ? -2.84275  -8.11165  16.83707  1.000 32.64664 -1 401 A1L46 A O04 1 
HETATM 4565 O O05 . A1L46 C 2 .   ? -0.67012  -11.71314 22.22050  1.000 38.11992 ?  401 A1L46 A O05 1 
HETATM 4566 O O06 . A1L46 C 2 .   ? -0.10983  -10.60043 20.42897  1.000 28.79496 -1 401 A1L46 A O06 1 
HETATM 4567 C C1  . GOL   D 3 .   ? -3.28987  -1.97696  19.04806  1.000 36.41743 ?  402 GOL   A C1  1 
HETATM 4568 O O1  . GOL   D 3 .   ? -4.03822  -2.26970  20.18427  1.000 35.43170 ?  402 GOL   A O1  1 
HETATM 4569 C C2  . GOL   D 3 .   ? -1.80904  -2.18854  19.41466  1.000 31.31904 ?  402 GOL   A C2  1 
HETATM 4570 O O2  . GOL   D 3 .   ? -1.53407  -3.50962  19.72889  1.000 33.25455 ?  402 GOL   A O2  1 
HETATM 4571 C C3  . GOL   D 3 .   ? -1.03800  -1.70917  18.17264  1.000 30.95900 ?  402 GOL   A C3  1 
HETATM 4572 O O3  . GOL   D 3 .   ? 0.21124   -1.28412  18.61462  1.000 33.08411 ?  402 GOL   A O3  1 
HETATM 4573 C C1  . GOL   E 3 .   ? -11.82509 -7.69016  18.33968  1.000 18.47322 ?  403 GOL   A C1  1 
HETATM 4574 O O1  . GOL   E 3 .   ? -12.54270 -8.73063  18.91980  1.000 33.60267 ?  403 GOL   A O1  1 
HETATM 4575 C C2  . GOL   E 3 .   ? -10.39740 -8.21856  18.09658  1.000 25.95149 ?  403 GOL   A C2  1 
HETATM 4576 O O2  . GOL   E 3 .   ? -9.79835  -8.66827  19.26113  1.000 38.70760 ?  403 GOL   A O2  1 
HETATM 4577 C C3  . GOL   E 3 .   ? -10.56817 -9.33932  17.06106  1.000 33.34194 ?  403 GOL   A C3  1 
HETATM 4578 O O3  . GOL   E 3 .   ? -9.29221  -9.68949  16.62298  1.000 34.66563 ?  403 GOL   A O3  1 
HETATM 4579 C C01 . A1L46 F 2 .   ? -0.74691  7.85848   33.62545  1.000 20.50008 ?  401 A1L46 B C01 1 
HETATM 4580 C C02 . A1L46 F 2 .   ? -1.76942  8.69333   34.08365  1.000 27.49296 ?  401 A1L46 B C02 1 
HETATM 4581 C C03 . A1L46 F 2 .   ? -1.47286  9.76432   34.91775  1.000 24.01909 ?  401 A1L46 B C03 1 
HETATM 4582 C C04 . A1L46 F 2 .   ? -0.16077  9.98058   35.27750  1.000 28.83929 ?  401 A1L46 B C04 1 
HETATM 4583 C C05 . A1L46 F 2 .   ? 0.83915   9.16334   34.82786  1.000 27.31347 ?  401 A1L46 B C05 1 
HETATM 4584 C C06 . A1L46 F 2 .   ? 0.57429   8.09352   33.99792  1.000 27.09510 ?  401 A1L46 B C06 1 
HETATM 4585 C C07 . A1L46 F 2 .   ? 1.74577   10.76149  36.13685  1.000 27.68427 ?  401 A1L46 B C07 1 
HETATM 4586 C C08 . A1L46 F 2 .   ? 2.07545   9.67402   35.39182  1.000 26.11393 ?  401 A1L46 B C08 1 
HETATM 4587 C C09 . A1L46 F 2 .   ? 2.74859   11.57190  36.89549  1.000 33.48982 ?  401 A1L46 B C09 1 
HETATM 4588 C C10 . A1L46 F 2 .   ? 4.29656   9.70449   36.41835  1.000 28.36305 ?  401 A1L46 B C10 1 
HETATM 4589 C C11 . A1L46 F 2 .   ? 3.46494   9.17942   35.24014  1.000 26.25107 ?  401 A1L46 B C11 1 
HETATM 4590 C C12 . A1L46 F 2 .   ? 5.74286   9.38072   36.18512  1.000 29.65608 ?  401 A1L46 B C12 1 
HETATM 4591 C C13 . A1L46 F 2 .   ? 2.53716   11.31981  38.38909  1.000 31.19426 ?  401 A1L46 B C13 1 
HETATM 4592 C C14 . A1L46 F 2 .   ? 2.58972   13.07173  36.62145  1.000 31.60320 ?  401 A1L46 B C14 1 
HETATM 4593 C C15 . A1L46 F 2 .   ? 2.05024   13.38755  35.22340  1.000 31.70789 ?  401 A1L46 B C15 1 
HETATM 4594 C C16 . A1L46 F 2 .   ? 3.16776   13.40720  34.18267  1.000 39.81773 ?  401 A1L46 B C16 1 
HETATM 4595 N N01 . A1L46 F 2 .   ? 0.34698   10.97315  36.09324  1.000 25.29221 ?  401 A1L46 B N01 1 
HETATM 4596 N N02 . A1L46 F 2 .   ? 4.14144   11.18093  36.51709  1.000 28.99523 ?  401 A1L46 B N02 1 
HETATM 4597 O O01 . A1L46 F 2 .   ? 6.54406   10.29728  35.86440  1.000 32.49507 -1 401 A1L46 B O01 1 
HETATM 4598 O O02 . A1L46 F 2 .   ? 6.15802   8.19803   36.30761  1.000 28.16162 ?  401 A1L46 B O02 1 
HETATM 4599 O O03 . A1L46 F 2 .   ? 1.41220   11.54179  38.91036  1.000 30.98163 ?  401 A1L46 B O03 1 
HETATM 4600 O O04 . A1L46 F 2 .   ? 3.48124   10.89085  39.10330  1.000 27.53348 -1 401 A1L46 B O04 1 
HETATM 4601 O O05 . A1L46 F 2 .   ? 4.17246   12.66199  34.31817  1.000 34.66512 ?  401 A1L46 B O05 1 
HETATM 4602 O O06 . A1L46 F 2 .   ? 3.08228   14.17152  33.18420  1.000 36.31815 -1 401 A1L46 B O06 1 
HETATM 4603 C C1  . GOL   G 3 .   ? -6.04131  10.67038  42.12962  1.000 32.16034 ?  402 GOL   B C1  1 
HETATM 4604 O O1  . GOL   G 3 .   ? -7.20772  11.22535  42.64843  1.000 47.43852 ?  402 GOL   B O1  1 
HETATM 4605 C C2  . GOL   G 3 .   ? -5.25124  11.81909  41.46777  1.000 33.09491 ?  402 GOL   B C2  1 
HETATM 4606 O O2  . GOL   G 3 .   ? -4.50090  12.52718  42.39463  1.000 40.71299 ?  402 GOL   B O2  1 
HETATM 4607 C C3  . GOL   G 3 .   ? -4.37432  11.12722  40.39547  1.000 33.76025 ?  402 GOL   B C3  1 
HETATM 4608 O O3  . GOL   G 3 .   ? -3.81242  12.13251  39.61157  1.000 43.76052 ?  402 GOL   B O3  1 
HETATM 4609 O O   . HOH   H 4 .   ? -4.87059  16.66719  16.12905  1.000 21.30266 ?  501 HOH   A O   1 
HETATM 4610 O O   . HOH   H 4 .   ? -20.30323 18.76697  19.27624  1.000 29.00138 ?  502 HOH   A O   1 
HETATM 4611 O O   . HOH   H 4 .   ? -19.97382 9.38864   13.75930  1.000 37.06206 ?  503 HOH   A O   1 
HETATM 4612 O O   . HOH   H 4 .   ? 4.99363   -10.33499 -3.99829  1.000 36.69932 ?  504 HOH   A O   1 
HETATM 4613 O O   . HOH   H 4 .   ? -25.87547 -5.35986  28.40639  1.000 32.04188 ?  505 HOH   A O   1 
HETATM 4614 O O   . HOH   H 4 .   ? -22.05164 16.82440  20.60306  1.000 35.69636 ?  506 HOH   A O   1 
HETATM 4615 O O   . HOH   H 4 .   ? -20.98101 -0.98189  12.61424  1.000 22.92979 ?  507 HOH   A O   1 
HETATM 4616 O O   . HOH   H 4 .   ? -14.56958 23.33147  8.96845   1.000 39.64267 ?  508 HOH   A O   1 
HETATM 4617 O O   . HOH   H 4 .   ? -16.84701 -1.13387  -1.32490  1.000 22.85889 ?  509 HOH   A O   1 
HETATM 4618 O O   . HOH   H 4 .   ? -11.71495 -0.01689  -7.34880  1.000 33.35729 ?  510 HOH   A O   1 
HETATM 4619 O O   . HOH   H 4 .   ? -9.58277  -19.59442 19.66980  1.000 33.06828 ?  511 HOH   A O   1 
HETATM 4620 O O   . HOH   H 4 .   ? -5.52550  -1.82480  -4.38660  1.000 28.91783 ?  512 HOH   A O   1 
HETATM 4621 O O   . HOH   H 4 .   ? -23.28498 16.67152  18.70583  1.000 39.56570 ?  513 HOH   A O   1 
HETATM 4622 O O   . HOH   H 4 .   ? -0.43016  -10.56425 16.41490  1.000 22.54295 ?  514 HOH   A O   1 
HETATM 4623 O O   . HOH   H 4 .   ? 3.76706   -15.50676 3.27368   1.000 37.11615 ?  515 HOH   A O   1 
HETATM 4624 O O   . HOH   H 4 .   ? -25.51930 8.12768   36.28939  1.000 25.55324 ?  516 HOH   A O   1 
HETATM 4625 O O   . HOH   H 4 .   ? -15.90077 7.37913   12.92921  1.000 21.05621 ?  517 HOH   A O   1 
HETATM 4626 O O   . HOH   H 4 .   ? -0.40732  -13.77900 13.33885  1.000 25.00341 ?  518 HOH   A O   1 
HETATM 4627 O O   . HOH   H 4 .   ? -20.16270 -10.65946 17.93598  1.000 33.79358 ?  519 HOH   A O   1 
HETATM 4628 O O   . HOH   H 4 .   ? -10.13450 1.77754   19.65266  1.000 19.98788 ?  520 HOH   A O   1 
HETATM 4629 O O   . HOH   H 4 .   ? -7.99101  22.23804  13.17806  1.000 35.16474 ?  521 HOH   A O   1 
HETATM 4630 O O   . HOH   H 4 .   ? -3.90662  7.81296   2.07820   1.000 28.16922 ?  522 HOH   A O   1 
HETATM 4631 O O   . HOH   H 4 .   ? 6.02797   11.05802  8.49605   1.000 31.56103 ?  523 HOH   A O   1 
HETATM 4632 O O   . HOH   H 4 .   ? -10.41435 9.55567   35.78277  1.000 21.66794 ?  524 HOH   A O   1 
HETATM 4633 O O   . HOH   H 4 .   ? -13.20992 0.49605   -4.08417  1.000 23.16573 ?  525 HOH   A O   1 
HETATM 4634 O O   . HOH   H 4 .   ? -0.27930  -20.58915 12.07257  1.000 28.55877 ?  526 HOH   A O   1 
HETATM 4635 O O   . HOH   H 4 .   ? 8.91296   -13.90364 11.64423  1.000 35.25628 ?  527 HOH   A O   1 
HETATM 4636 O O   . HOH   H 4 .   ? -3.84118  -13.70486 19.32394  1.000 24.87726 ?  528 HOH   A O   1 
HETATM 4637 O O   . HOH   H 4 .   ? 0.70103   2.85359   19.96993  1.000 23.44016 ?  529 HOH   A O   1 
HETATM 4638 O O   . HOH   H 4 .   ? -12.95509 8.17195   7.87374   1.000 19.75407 ?  530 HOH   A O   1 
HETATM 4639 O O   . HOH   H 4 .   ? 13.12127  16.70836  32.37566  1.000 36.51948 ?  531 HOH   A O   1 
HETATM 4640 O O   . HOH   H 4 .   ? -17.11983 -12.27556 7.15816   1.000 26.31434 ?  532 HOH   A O   1 
HETATM 4641 O O   . HOH   H 4 .   ? 8.77539   12.57032  23.34393  1.000 29.81367 ?  533 HOH   A O   1 
HETATM 4642 O O   . HOH   H 4 .   ? -1.86619  -9.37784  14.20194  1.000 27.08469 ?  534 HOH   A O   1 
HETATM 4643 O O   . HOH   H 4 .   ? 3.34554   -15.66619 0.69113   1.000 32.02623 ?  535 HOH   A O   1 
HETATM 4644 O O   . HOH   H 4 .   ? -21.19608 -1.57349  -0.84013  1.000 43.33692 ?  536 HOH   A O   1 
HETATM 4645 O O   . HOH   H 4 .   ? -0.01712  2.82361   11.31374  1.000 23.77821 ?  537 HOH   A O   1 
HETATM 4646 O O   . HOH   H 4 .   ? -1.04996  1.83110   -1.90182  1.000 22.79783 ?  538 HOH   A O   1 
HETATM 4647 O O   . HOH   H 4 .   ? -1.88222  -18.61386 10.78721  1.000 33.49807 ?  539 HOH   A O   1 
HETATM 4648 O O   . HOH   H 4 .   ? -3.74620  15.25006  19.53097  1.000 23.97060 ?  540 HOH   A O   1 
HETATM 4649 O O   . HOH   H 4 .   ? -13.25899 14.02397  30.01069  1.000 28.89825 ?  541 HOH   A O   1 
HETATM 4650 O O   . HOH   H 4 .   ? -21.00117 -8.71565  11.23607  1.000 25.61971 ?  542 HOH   A O   1 
HETATM 4651 O O   . HOH   H 4 .   ? 5.89774   6.87449   18.18823  1.000 22.28735 ?  543 HOH   A O   1 
HETATM 4652 O O   . HOH   H 4 .   ? -8.95049  2.68415   12.65369  1.000 15.22696 ?  544 HOH   A O   1 
HETATM 4653 O O   . HOH   H 4 .   ? 12.60861  -0.31041  4.56890   1.000 29.08568 ?  545 HOH   A O   1 
HETATM 4654 O O   . HOH   H 4 .   ? -4.37076  12.34128  34.18896  1.000 26.93273 ?  546 HOH   A O   1 
HETATM 4655 O O   . HOH   H 4 .   ? -11.14301 -2.18407  22.80111  1.000 17.63798 ?  547 HOH   A O   1 
HETATM 4656 O O   . HOH   H 4 .   ? -2.47684  2.25836   9.67636   1.000 22.81175 ?  548 HOH   A O   1 
HETATM 4657 O O   . HOH   H 4 .   ? -6.23434  22.20346  21.91948  1.000 32.69935 ?  549 HOH   A O   1 
HETATM 4658 O O   . HOH   H 4 .   ? -17.28213 4.27177   11.08204  1.000 23.75210 ?  550 HOH   A O   1 
HETATM 4659 O O   . HOH   H 4 .   ? -28.21818 0.91955   20.09288  1.000 34.36609 ?  551 HOH   A O   1 
HETATM 4660 O O   . HOH   H 4 .   ? 5.03150   3.31087   29.34728  1.000 24.91465 ?  552 HOH   A O   1 
HETATM 4661 O O   . HOH   H 4 .   ? 4.73459   1.18636   6.91476   1.000 20.67544 ?  553 HOH   A O   1 
HETATM 4662 O O   . HOH   H 4 .   ? -18.01797 1.80598   7.42302   1.000 30.05322 ?  554 HOH   A O   1 
HETATM 4663 O O   . HOH   H 4 .   ? -6.06504  2.19016   17.82786  1.000 15.08173 ?  555 HOH   A O   1 
HETATM 4664 O O   . HOH   H 4 .   ? -8.83014  -12.40327 19.17551  1.000 33.18891 ?  556 HOH   A O   1 
HETATM 4665 O O   . HOH   H 4 .   ? 8.81287   -14.65337 27.76622  1.000 29.41959 ?  557 HOH   A O   1 
HETATM 4666 O O   . HOH   H 4 .   ? 11.28307  6.03347   15.13114  1.000 28.76420 ?  558 HOH   A O   1 
HETATM 4667 O O   . HOH   H 4 .   ? -7.60240  8.85986   9.74995   1.000 18.23232 ?  559 HOH   A O   1 
HETATM 4668 O O   . HOH   H 4 .   ? -13.05913 -7.48470  15.25135  1.000 27.20038 ?  560 HOH   A O   1 
HETATM 4669 O O   . HOH   H 4 .   ? -35.59186 1.13015   22.63145  1.000 46.90441 ?  561 HOH   A O   1 
HETATM 4670 O O   . HOH   H 4 .   ? 2.45131   19.28055  22.33327  1.000 41.91292 ?  562 HOH   A O   1 
HETATM 4671 O O   . HOH   H 4 .   ? -7.32538  4.44076   -1.88798  1.000 27.56701 ?  563 HOH   A O   1 
HETATM 4672 O O   . HOH   H 4 .   ? 3.01333   20.50065  28.87053  1.000 45.91432 ?  564 HOH   A O   1 
HETATM 4673 O O   . HOH   H 4 .   ? -16.68784 17.15371  30.23443  1.000 29.58694 ?  565 HOH   A O   1 
HETATM 4674 O O   . HOH   H 4 .   ? 1.42048   0.37264   21.05368  1.000 26.76052 ?  566 HOH   A O   1 
HETATM 4675 O O   . HOH   H 4 .   ? -3.07175  -5.40908  6.93056   1.000 25.26004 ?  567 HOH   A O   1 
HETATM 4676 O O   . HOH   H 4 .   ? -15.23799 20.07998  16.11600  1.000 18.57515 ?  568 HOH   A O   1 
HETATM 4677 O O   . HOH   H 4 .   ? -13.16181 21.19976  25.25214  1.000 31.23369 ?  569 HOH   A O   1 
HETATM 4678 O O   . HOH   H 4 .   ? -9.44601  6.77133   10.24543  1.000 20.31353 ?  570 HOH   A O   1 
HETATM 4679 O O   . HOH   H 4 .   ? -11.27555 0.66698   17.57245  1.000 17.11615 ?  571 HOH   A O   1 
HETATM 4680 O O   . HOH   H 4 .   ? -8.50022  5.76344   12.47315  1.000 15.62811 ?  572 HOH   A O   1 
HETATM 4681 O O   . HOH   H 4 .   ? -10.94599 3.79825   13.63897  1.000 15.94351 ?  573 HOH   A O   1 
HETATM 4682 O O   . HOH   H 4 .   ? -22.65878 -3.64439  26.00287  1.000 33.37542 ?  574 HOH   A O   1 
HETATM 4683 O O   . HOH   H 4 .   ? -25.32424 -5.45797  6.22910   1.000 38.82044 ?  575 HOH   A O   1 
HETATM 4684 O O   . HOH   H 4 .   ? -7.45456  6.98713   1.90392   1.000 27.57654 ?  576 HOH   A O   1 
HETATM 4685 O O   . HOH   H 4 .   ? -6.48585  -18.34080 -7.29739  1.000 44.45679 ?  577 HOH   A O   1 
HETATM 4686 O O   . HOH   H 4 .   ? -24.80937 12.12545  33.67649  1.000 31.68959 ?  578 HOH   A O   1 
HETATM 4687 O O   . HOH   H 4 .   ? -7.91768  -16.17900 11.89818  1.000 34.35520 ?  579 HOH   A O   1 
HETATM 4688 O O   . HOH   H 4 .   ? -5.63480  -26.58225 15.59796  1.000 42.68511 ?  580 HOH   A O   1 
HETATM 4689 O O   . HOH   H 4 .   ? -5.70288  0.70769   20.52281  1.000 18.62147 ?  581 HOH   A O   1 
HETATM 4690 O O   . HOH   H 4 .   ? 5.86442   -0.14234  28.99316  1.000 19.61735 ?  582 HOH   A O   1 
HETATM 4691 O O   . HOH   H 4 .   ? -9.46995  -12.74560 -9.14476  1.000 43.85286 ?  583 HOH   A O   1 
HETATM 4692 O O   . HOH   H 4 .   ? -10.54003 6.22139   29.48727  1.000 17.70516 ?  584 HOH   A O   1 
HETATM 4693 O O   . HOH   H 4 .   ? -12.51472 5.89982   3.04393   1.000 28.24683 ?  585 HOH   A O   1 
HETATM 4694 O O   . HOH   H 4 .   ? -11.79552 22.34445  5.65244   1.000 43.89647 ?  586 HOH   A O   1 
HETATM 4695 O O   . HOH   H 4 .   ? 10.40472  -1.57997  3.94317   1.000 36.23595 ?  587 HOH   A O   1 
HETATM 4696 O O   . HOH   H 4 .   ? -12.29987 7.47538   28.17438  1.000 24.12890 ?  588 HOH   A O   1 
HETATM 4697 O O   . HOH   H 4 .   ? -2.60234  5.91774   7.82373   1.000 24.07184 ?  589 HOH   A O   1 
HETATM 4698 O O   . HOH   H 4 .   ? -7.39282  -13.59698 -9.66571  1.000 39.75223 ?  590 HOH   A O   1 
HETATM 4699 O O   . HOH   H 4 .   ? 8.82210   -12.08915 9.85432   1.000 43.12923 ?  591 HOH   A O   1 
HETATM 4700 O O   . HOH   H 4 .   ? -1.18420  5.75716   10.23162  1.000 25.71572 ?  592 HOH   A O   1 
HETATM 4701 O O   . HOH   H 4 .   ? -6.52613  20.76454  26.04791  1.000 23.41342 ?  593 HOH   A O   1 
HETATM 4702 O O   . HOH   H 4 .   ? -9.95142  -14.82603 10.73674  1.000 26.71672 ?  594 HOH   A O   1 
HETATM 4703 O O   . HOH   H 4 .   ? -8.16143  0.37098   19.93568  1.000 28.47065 ?  595 HOH   A O   1 
HETATM 4704 O O   . HOH   H 4 .   ? 7.75138   -15.67487 22.82611  1.000 40.80231 ?  596 HOH   A O   1 
HETATM 4705 O O   . HOH   H 4 .   ? -26.729   14.650    29.421    1.000 32.84068 ?  597 HOH   A O   1 
HETATM 4706 O O   . HOH   H 4 .   ? -23.92880 -8.95236  11.59700  1.000 27.58488 ?  598 HOH   A O   1 
HETATM 4707 O O   . HOH   H 4 .   ? -15.58373 21.59877  26.42577  1.000 24.91470 ?  599 HOH   A O   1 
HETATM 4708 O O   . HOH   H 4 .   ? -10.614   22.180    26.386    1.000 34.45440 ?  600 HOH   A O   1 
HETATM 4709 O O   . HOH   H 4 .   ? 7.90633   -12.51616 27.57008  1.000 31.11132 ?  601 HOH   A O   1 
HETATM 4710 O O   . HOH   H 4 .   ? -26.59795 -6.40555  26.12449  1.000 45.34858 ?  602 HOH   A O   1 
HETATM 4711 O O   . HOH   H 4 .   ? -3.00326  18.95917  15.22701  1.000 37.32751 ?  603 HOH   A O   1 
HETATM 4712 O O   . HOH   H 4 .   ? 8.51097   -17.49481 24.02914  1.000 43.31599 ?  604 HOH   A O   1 
HETATM 4713 O O   . HOH   H 4 .   ? 4.85845   9.19501   18.67322  1.000 31.61601 ?  605 HOH   A O   1 
HETATM 4714 O O   . HOH   H 4 .   ? -27.96041 5.73036   18.54126  1.000 32.24872 ?  606 HOH   A O   1 
HETATM 4715 O O   . HOH   H 4 .   ? -16.81210 3.58986   6.60121   1.000 36.34250 ?  607 HOH   A O   1 
HETATM 4716 O O   . HOH   H 4 .   ? -23.62499 -2.46243  13.34209  1.000 36.66959 ?  608 HOH   A O   1 
HETATM 4717 O O   . HOH   H 4 .   ? -25.81896 -7.34492  12.06538  1.000 32.13888 ?  609 HOH   A O   1 
HETATM 4718 O O   . HOH   H 4 .   ? -27.45715 3.11467   19.43700  1.000 34.88802 ?  610 HOH   A O   1 
HETATM 4719 O O   . HOH   H 4 .   ? -6.96726  23.26579  24.42287  1.000 27.25423 ?  611 HOH   A O   1 
HETATM 4720 O O   . HOH   H 4 .   ? -19.478   21.598    23.717    1.000 21.52839 ?  612 HOH   A O   1 
HETATM 4721 O O   . HOH   H 4 .   ? 0.51166   8.89430   0.36009   1.000 33.97352 ?  613 HOH   A O   1 
HETATM 4722 O O   . HOH   H 4 .   ? -15.32561 14.65425  31.23020  1.000 32.72430 ?  614 HOH   A O   1 
HETATM 4723 O O   . HOH   H 4 .   ? 0.40648   4.32774   -2.76245  1.000 41.58269 ?  615 HOH   A O   1 
HETATM 4724 O O   . HOH   H 4 .   ? -1.39585  7.68277   0.20060   1.000 37.82678 ?  616 HOH   A O   1 
HETATM 4725 O O   . HOH   I 4 .   ? -11.42610 5.06835   51.23761  1.000 31.22577 ?  501 HOH   B O   1 
HETATM 4726 O O   . HOH   I 4 .   ? -22.74775 1.36708   40.30959  1.000 34.23742 ?  502 HOH   B O   1 
HETATM 4727 O O   . HOH   I 4 .   ? -6.24365  22.55835  61.35593  1.000 42.19174 ?  503 HOH   B O   1 
HETATM 4728 O O   . HOH   I 4 .   ? -7.69472  -3.98155  48.65718  1.000 32.64421 ?  504 HOH   B O   1 
HETATM 4729 O O   . HOH   I 4 .   ? 7.62826   21.25791  44.11561  1.000 35.47096 ?  505 HOH   B O   1 
HETATM 4730 O O   . HOH   I 4 .   ? -0.19330  -13.69328 40.94791  1.000 24.77639 ?  506 HOH   B O   1 
HETATM 4731 O O   . HOH   I 4 .   ? 14.04362  -9.56632  16.12217  1.000 38.12499 ?  507 HOH   B O   1 
HETATM 4732 O O   . HOH   I 4 .   ? 13.30678  -9.80099  43.01056  1.000 38.59645 ?  508 HOH   B O   1 
HETATM 4733 O O   . HOH   I 4 .   ? -11.37144 -10.78810 48.68087  1.000 40.36748 ?  509 HOH   B O   1 
HETATM 4734 O O   . HOH   I 4 .   ? 21.36305  1.25624   43.09317  1.000 40.25536 ?  510 HOH   B O   1 
HETATM 4735 O O   . HOH   I 4 .   ? 19.16644  16.67440  58.36620  1.000 47.45196 ?  511 HOH   B O   1 
HETATM 4736 O O   . HOH   I 4 .   ? 16.60414  17.49395  50.22949  1.000 28.77074 ?  512 HOH   B O   1 
HETATM 4737 O O   . HOH   I 4 .   ? 14.61904  6.43245   16.32953  1.000 34.15980 ?  513 HOH   B O   1 
HETATM 4738 O O   . HOH   I 4 .   ? 0.35661   -15.91495 30.19885  1.000 27.26559 ?  514 HOH   B O   1 
HETATM 4739 O O   . HOH   I 4 .   ? -9.65204  -16.54661 45.70017  1.000 28.91532 ?  515 HOH   B O   1 
HETATM 4740 O O   . HOH   I 4 .   ? -11.73084 -8.87441  49.76214  1.000 31.63559 ?  516 HOH   B O   1 
HETATM 4741 O O   . HOH   I 4 .   ? -22.20325 10.68362  39.70956  1.000 33.57691 ?  517 HOH   B O   1 
HETATM 4742 O O   . HOH   I 4 .   ? -6.86604  2.33965   54.73916  1.000 30.65638 ?  518 HOH   B O   1 
HETATM 4743 O O   . HOH   I 4 .   ? 6.45473   -2.12709  57.76458  1.000 35.46105 ?  519 HOH   B O   1 
HETATM 4744 O O   . HOH   I 4 .   ? 15.69717  6.32909   28.86422  1.000 30.91817 ?  520 HOH   B O   1 
HETATM 4745 O O   . HOH   I 4 .   ? -4.64610  15.88452  53.86147  1.000 29.32488 ?  521 HOH   B O   1 
HETATM 4746 O O   . HOH   I 4 .   ? -5.37220  2.84971   42.28591  1.000 20.77155 ?  522 HOH   B O   1 
HETATM 4747 O O   . HOH   I 4 .   ? 0.07453   -2.51354  58.77045  1.000 31.82537 ?  523 HOH   B O   1 
HETATM 4748 O O   . HOH   I 4 .   ? -7.31354  -9.32247  24.47588  1.000 20.10122 ?  524 HOH   B O   1 
HETATM 4749 O O   . HOH   I 4 .   ? 20.017    0.889     57.898    1.000 22.58585 ?  525 HOH   B O   1 
HETATM 4750 O O   . HOH   I 4 .   ? -10.20207 13.18025  51.87797  1.000 27.44313 ?  526 HOH   B O   1 
HETATM 4751 O O   . HOH   I 4 .   ? 4.64248   11.92940  41.15227  1.000 35.65237 ?  527 HOH   B O   1 
HETATM 4752 O O   . HOH   I 4 .   ? 13.68720  0.58307   44.60746  1.000 26.52398 ?  528 HOH   B O   1 
HETATM 4753 O O   . HOH   I 4 .   ? -10.92935 11.89443  45.10215  1.000 34.03199 ?  529 HOH   B O   1 
HETATM 4754 O O   . HOH   I 4 .   ? 9.64450   -14.04774 42.18452  1.000 35.86732 ?  530 HOH   B O   1 
HETATM 4755 O O   . HOH   I 4 .   ? -11.90821 -17.50253 36.01717  1.000 23.75218 ?  531 HOH   B O   1 
HETATM 4756 O O   . HOH   I 4 .   ? -26.87768 -3.23124  31.59622  1.000 27.37314 ?  532 HOH   B O   1 
HETATM 4757 O O   . HOH   I 4 .   ? 3.54365   -0.96181  24.70879  1.000 20.89659 ?  533 HOH   B O   1 
HETATM 4758 O O   . HOH   I 4 .   ? 7.55781   -0.73501  43.15037  1.000 26.16753 ?  534 HOH   B O   1 
HETATM 4759 O O   . HOH   I 4 .   ? 16.25095  -9.31249  31.19054  1.000 32.27857 ?  535 HOH   B O   1 
HETATM 4760 O O   . HOH   I 4 .   ? -13.40353 -5.91253  25.91010  1.000 28.55615 ?  536 HOH   B O   1 
HETATM 4761 O O   . HOH   I 4 .   ? -7.42714  5.58023   37.65771  1.000 15.14867 ?  537 HOH   B O   1 
HETATM 4762 O O   . HOH   I 4 .   ? -6.10263  -17.52025 33.08255  1.000 23.47307 ?  538 HOH   B O   1 
HETATM 4763 O O   . HOH   I 4 .   ? 2.93125   2.87080   62.56644  1.000 35.24754 ?  539 HOH   B O   1 
HETATM 4764 O O   . HOH   I 4 .   ? -5.18731  1.41061   40.10715  1.000 21.13745 ?  540 HOH   B O   1 
HETATM 4765 O O   . HOH   I 4 .   ? -24.30901 -3.38251  48.96943  1.000 33.60914 ?  541 HOH   B O   1 
HETATM 4766 O O   . HOH   I 4 .   ? 19.86541  4.50073   24.88239  1.000 30.55966 ?  542 HOH   B O   1 
HETATM 4767 O O   . HOH   I 4 .   ? 2.51011   23.39590  53.25076  1.000 45.43593 ?  543 HOH   B O   1 
HETATM 4768 O O   . HOH   I 4 .   ? -0.87257  -3.82050  48.40455  1.000 24.54426 ?  544 HOH   B O   1 
HETATM 4769 O O   . HOH   I 4 .   ? -1.48579  18.94801  65.48615  1.000 51.13699 ?  545 HOH   B O   1 
HETATM 4770 O O   . HOH   I 4 .   ? 8.98059   -4.95218  34.61498  1.000 26.80190 ?  546 HOH   B O   1 
HETATM 4771 O O   . HOH   I 4 .   ? 23.92142  15.04427  51.19348  1.000 41.46354 ?  547 HOH   B O   1 
HETATM 4772 O O   . HOH   I 4 .   ? -0.27567  -2.18054  55.96527  1.000 31.09826 ?  548 HOH   B O   1 
HETATM 4773 O O   . HOH   I 4 .   ? 6.68116   -3.24890  47.43558  1.000 23.30732 ?  549 HOH   B O   1 
HETATM 4774 O O   . HOH   I 4 .   ? -4.37915  -19.12397 36.46984  1.000 23.06036 ?  550 HOH   B O   1 
HETATM 4775 O O   . HOH   I 4 .   ? 8.62788   -9.56689  22.65972  1.000 28.63788 ?  551 HOH   B O   1 
HETATM 4776 O O   . HOH   I 4 .   ? 15.92930  19.75477  46.37891  1.000 36.99624 ?  552 HOH   B O   1 
HETATM 4777 O O   . HOH   I 4 .   ? -2.10527  4.55830   62.45403  1.000 38.29532 ?  553 HOH   B O   1 
HETATM 4778 O O   . HOH   I 4 .   ? 3.72871   -16.09476 34.68379  1.000 35.23560 ?  554 HOH   B O   1 
HETATM 4779 O O   . HOH   I 4 .   ? 4.90869   1.87436   24.42996  1.000 17.31108 ?  555 HOH   B O   1 
HETATM 4780 O O   . HOH   I 4 .   ? 15.12992  -5.21524  34.79122  1.000 23.76957 ?  556 HOH   B O   1 
HETATM 4781 O O   . HOH   I 4 .   ? -0.94036  0.33882   45.76051  1.000 16.31660 ?  557 HOH   B O   1 
HETATM 4782 O O   . HOH   I 4 .   ? -3.68950  -0.56460  45.90076  1.000 22.70310 ?  558 HOH   B O   1 
HETATM 4783 O O   . HOH   I 4 .   ? -1.25743  -12.80469 37.54081  1.000 25.20775 ?  559 HOH   B O   1 
HETATM 4784 O O   . HOH   I 4 .   ? -23.44705 7.53589   45.23982  1.000 32.71165 ?  560 HOH   B O   1 
HETATM 4785 O O   . HOH   I 4 .   ? 25.65904  6.17874   28.47091  1.000 33.74944 ?  561 HOH   B O   1 
HETATM 4786 O O   . HOH   I 4 .   ? -16.909   -18.729   40.488    1.000 37.38926 ?  562 HOH   B O   1 
HETATM 4787 O O   . HOH   I 4 .   ? -8.73179  21.13218  44.37858  1.000 31.91683 ?  563 HOH   B O   1 
HETATM 4788 O O   . HOH   I 4 .   ? 3.89784   -26.26429 29.32324  1.000 38.30532 ?  564 HOH   B O   1 
HETATM 4789 O O   . HOH   I 4 .   ? 9.11541   -10.48114 27.95745  1.000 27.90278 ?  565 HOH   B O   1 
HETATM 4790 O O   . HOH   I 4 .   ? -3.77298  3.07528   38.72461  1.000 24.74310 ?  566 HOH   B O   1 
HETATM 4791 O O   . HOH   I 4 .   ? -29.93619 -0.76725  34.94860  1.000 32.66670 ?  567 HOH   B O   1 
HETATM 4792 O O   . HOH   I 4 .   ? -4.47687  14.92542  69.25354  1.000 51.42998 ?  568 HOH   B O   1 
HETATM 4793 O O   . HOH   I 4 .   ? -14.00018 -10.47280 32.38826  1.000 28.11795 ?  569 HOH   B O   1 
HETATM 4794 O O   . HOH   I 4 .   ? 5.80643   0.13561   45.46562  1.000 27.40593 ?  570 HOH   B O   1 
HETATM 4795 O O   . HOH   I 4 .   ? -1.62470  2.10291   37.29575  1.000 16.19311 ?  571 HOH   B O   1 
HETATM 4796 O O   . HOH   I 4 .   ? -3.68015  -9.36977  52.61191  1.000 30.92851 ?  572 HOH   B O   1 
HETATM 4797 O O   . HOH   I 4 .   ? -21.60658 4.18449   47.80333  1.000 44.64196 ?  573 HOH   B O   1 
HETATM 4798 O O   . HOH   I 4 .   ? -18.62656 8.68653   39.75127  1.000 34.89037 ?  574 HOH   B O   1 
HETATM 4799 O O   . HOH   I 4 .   ? 7.37003   7.68421   48.00420  1.000 24.19329 ?  575 HOH   B O   1 
HETATM 4800 O O   . HOH   I 4 .   ? -30.95995 -5.33994  35.91198  1.000 45.66593 ?  576 HOH   B O   1 
HETATM 4801 O O   . HOH   I 4 .   ? -1.02931  0.78173   39.63697  1.000 23.11106 ?  577 HOH   B O   1 
HETATM 4802 O O   . HOH   I 4 .   ? 9.37765   15.48378  23.90254  1.000 30.19986 ?  578 HOH   B O   1 
HETATM 4803 O O   . HOH   I 4 .   ? 16.82514  -6.63811  41.90957  1.000 42.32127 ?  579 HOH   B O   1 
HETATM 4804 O O   . HOH   I 4 .   ? 0.61250   -5.97961  47.76084  1.000 30.16863 ?  580 HOH   B O   1 
HETATM 4805 O O   . HOH   I 4 .   ? -9.99896  9.32820   40.71765  1.000 33.69811 ?  581 HOH   B O   1 
HETATM 4806 O O   . HOH   I 4 .   ? -7.82455  -0.45699  51.31740  1.000 33.00064 ?  582 HOH   B O   1 
HETATM 4807 O O   . HOH   I 4 .   ? -17.04383 -10.28909 29.69936  1.000 29.88681 ?  583 HOH   B O   1 
HETATM 4808 O O   . HOH   I 4 .   ? 9.98031   20.77424  45.99356  1.000 33.00558 ?  584 HOH   B O   1 
HETATM 4809 O O   . HOH   I 4 .   ? 3.83034   -0.49340  35.20879  1.000 21.70387 ?  585 HOH   B O   1 
HETATM 4810 O O   . HOH   I 4 .   ? -1.12052  -17.59586 48.05934  1.000 32.64783 ?  586 HOH   B O   1 
HETATM 4811 O O   . HOH   I 4 .   ? 8.26070   -7.52506  34.40388  1.000 23.48736 ?  587 HOH   B O   1 
HETATM 4812 O O   . HOH   I 4 .   ? -17.49778 -3.63147  50.43376  1.000 28.00904 ?  588 HOH   B O   1 
HETATM 4813 O O   . HOH   I 4 .   ? -2.78084  -5.02923  52.23767  1.000 28.82848 ?  589 HOH   B O   1 
HETATM 4814 O O   . HOH   I 4 .   ? -0.75994  -2.65743  45.50575  1.000 22.36476 ?  590 HOH   B O   1 
HETATM 4815 O O   . HOH   I 4 .   ? -0.28131  -15.24727 37.13900  1.000 29.32404 ?  591 HOH   B O   1 
HETATM 4816 O O   . HOH   I 4 .   ? -12.614   15.039    45.363    1.000 33.06592 ?  592 HOH   B O   1 
HETATM 4817 O O   . HOH   I 4 .   ? -28.83933 2.77583   36.97202  1.000 33.30072 ?  593 HOH   B O   1 
HETATM 4818 O O   . HOH   I 4 .   ? -11.57451 -11.04682 55.01294  1.000 39.08737 ?  594 HOH   B O   1 
HETATM 4819 O O   . HOH   I 4 .   ? -23.92826 -7.45927  31.15738  1.000 31.56626 ?  595 HOH   B O   1 
HETATM 4820 O O   . HOH   I 4 .   ? -1.56830  -18.52884 45.57699  1.000 32.89279 ?  596 HOH   B O   1 
HETATM 4821 O O   . HOH   I 4 .   ? -6.27948  -15.07420 29.01385  1.000 30.84720 ?  597 HOH   B O   1 
HETATM 4822 O O   . HOH   I 4 .   ? 7.14286   15.97475  40.79413  1.000 30.24428 ?  598 HOH   B O   1 
HETATM 4823 O O   . HOH   I 4 .   ? 5.03669   1.77574   33.98597  1.000 25.38460 ?  599 HOH   B O   1 
HETATM 4824 O O   . HOH   I 4 .   ? 2.02302   -15.89709 40.78138  1.000 39.39243 ?  600 HOH   B O   1 
HETATM 4825 O O   . HOH   I 4 .   ? -12.65415 13.64954  53.16668  1.000 36.55383 ?  601 HOH   B O   1 
HETATM 4826 O O   . HOH   I 4 .   ? -11.66235 -3.86244  33.77556  1.000 17.17962 ?  602 HOH   B O   1 
HETATM 4827 O O   . HOH   I 4 .   ? -8.59635  -17.12342 32.85505  1.000 30.93350 ?  603 HOH   B O   1 
HETATM 4828 O O   . HOH   I 4 .   ? -8.47590  2.47758   52.01767  1.000 33.41868 ?  604 HOH   B O   1 
HETATM 4829 O O   . HOH   I 4 .   ? -18.69474 -15.86221 43.56526  1.000 42.96590 ?  605 HOH   B O   1 
HETATM 4830 O O   . HOH   I 4 .   ? -10.16620 -2.84835  31.70474  1.000 19.71174 ?  606 HOH   B O   1 
HETATM 4831 O O   . HOH   I 4 .   ? 1.09217   -17.97933 28.26558  1.000 33.58825 ?  607 HOH   B O   1 
HETATM 4832 O O   . HOH   I 4 .   ? 6.41914   -3.13379  44.53352  1.000 23.97905 ?  608 HOH   B O   1 
HETATM 4833 O O   . HOH   I 4 .   ? -5.30999  -16.85179 30.22916  1.000 31.00183 ?  609 HOH   B O   1 
HETATM 4834 O O   . HOH   I 4 .   ? 1.41443   -16.83514 37.23425  1.000 40.84823 ?  610 HOH   B O   1 
HETATM 4835 O O   . HOH   I 4 .   ? -0.94914  4.66854   36.55610  1.000 21.91294 ?  611 HOH   B O   1 
HETATM 4836 O O   . HOH   I 4 .   ? -5.24463  -10.72206 23.52573  1.000 29.38222 ?  612 HOH   B O   1 
HETATM 4837 O O   . HOH   I 4 .   ? -15.97056 -14.86412 43.52424  1.000 37.07371 ?  613 HOH   B O   1 
HETATM 4838 O O   . HOH   I 4 .   ? -26.60019 -8.91488  31.60915  1.000 36.81323 ?  614 HOH   B O   1 
HETATM 4839 O O   . HOH   I 4 .   ? 7.11816   -1.42304  60.29875  1.000 27.40981 ?  615 HOH   B O   1 
HETATM 4840 O O   . HOH   I 4 .   ? 0.12490   -17.02614 41.40184  1.000 39.02223 ?  616 HOH   B O   1 
HETATM 4841 O O   . HOH   I 4 .   ? -23.07939 -7.18238  28.77117  1.000 39.80290 ?  617 HOH   B O   1 
HETATM 4842 O O   . HOH   I 4 .   ? -16.66949 -12.11314 28.31840  1.000 33.30893 ?  618 HOH   B O   1 
HETATM 4843 O O   . HOH   I 4 .   ? -14.14653 14.37751  58.26638  1.000 34.13362 ?  619 HOH   B O   1 
HETATM 4844 O O   . HOH   I 4 .   ? -15.32942 15.08390  56.35363  1.000 40.20006 ?  620 HOH   B O   1 
# 
