data_8K0V
# 
_entry.id   8K0V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8K0V         pdb_00008k0v 10.2210/pdb8k0v/pdb 
WWPDB D_1300039143 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-16 ? 
2 'Structure model' 1 1 2025-06-11 ? 
3 'Structure model' 1 2 2025-06-18 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 3 'Structure model' citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.page_first'     
3 2 'Structure model' '_citation.page_last'      
4 3 'Structure model' '_citation.page_first'     
5 3 'Structure model' '_citation.page_last'      
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8K0V 
_pdbx_database_status.recvd_initial_deposition_date   2023-07-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              huanglin36@mail.sysu.edu.cn 
_pdbx_contact_author.name_first         Lin 
_pdbx_contact_author.name_last          Huang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2121-365X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Huang, Y.' 1 ? 
'Lin, X.'   2 ? 
'Huang, L.' 3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   GE 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Angew.Chem.Int.Ed.Engl. 
_citation.journal_id_ASTM           ACIEAY 
_citation.journal_id_CSD            0179 
_citation.journal_id_ISSN           1521-3773 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            64 
_citation.language                  ? 
_citation.page_first                e202504107 
_citation.page_last                 e202504107 
_citation.title                     
'From Theophylline to Adenine or preQ 1 : Repurposing a DNA Aptamer Revealed by Crystal Structure Analysis.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1002/anie.202504107 
_citation.pdbx_database_id_PubMed   40101171 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lin, X.'    1  ? 
primary 'Huang, Y.'  2  ? 
primary 'Huang, J.'  3  ? 
primary 'Yuan, H.'   4  ? 
primary 'Luo, Y.'    5  ? 
primary 'Lu, Z.'     6  ? 
primary 'Ao, Y.'     7  ? 
primary 'Huang, J.'  8  ? 
primary 'Chen, S.B.' 9  ? 
primary 'Miao, Z.'   10 ? 
primary 'Huang, L.'  11 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     syn 'DNA (29-MER)'                    8918.707 1  ? ? ? ? 
2 non-polymer syn '3-methyl-7~{H}-purine-2,6-dione' 166.137  1  ? ? ? ? 
3 non-polymer syn 'SODIUM ION'                      22.990   4  ? ? ? ? 
4 water       nat water                             18.015   53 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           polydeoxyribonucleotide 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;(DG)(DC)(DG)(DG)(DT)(DG)(DG)(DT)(DC)(DT)(DA)(DT)(DT)(DC)(DA)(DT)(DA)(DG)(DG)(DC)
(DG)(DT)(DC)(DC)(DG)(DC)(DC)(DG)(DC)
;
_entity_poly.pdbx_seq_one_letter_code_can   GCGGTGGTCTATTCATAGGCGTCCGCCGC 
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '3-methyl-7~{H}-purine-2,6-dione' I7U 
3 'SODIUM ION'                      NA  
4 water                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1  DG n 
1 2  DC n 
1 3  DG n 
1 4  DG n 
1 5  DT n 
1 6  DG n 
1 7  DG n 
1 8  DT n 
1 9  DC n 
1 10 DT n 
1 11 DA n 
1 12 DT n 
1 13 DT n 
1 14 DC n 
1 15 DA n 
1 16 DT n 
1 17 DA n 
1 18 DG n 
1 19 DG n 
1 20 DC n 
1 21 DG n 
1 22 DT n 
1 23 DC n 
1 24 DC n 
1 25 DG n 
1 26 DC n 
1 27 DC n 
1 28 DG n 
1 29 DC n 
# 
_pdbx_entity_src_syn.entity_id              1 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       29 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
DA  'DNA linking' y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ?                             'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking' y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ?                             'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking' y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ?                             'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking' y "THYMIDINE-5'-MONOPHOSPHATE"         ?                             'C10 H15 N2 O8 P' 322.208 
HOH non-polymer   . WATER                                ?                             'H2 O'            18.015  
I7U non-polymer   . '3-methyl-7~{H}-purine-2,6-dione'    '3-Methylxanthine; 1076-22-8' 'C6 H6 N4 O2'     166.137 
NA  non-polymer   . 'SODIUM ION'                         ?                             'Na 1'            22.990  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1  DG 1  1  1  DG DG A . n 
A 1 2  DC 2  2  2  DC DC A . n 
A 1 3  DG 3  3  3  DG DG A . n 
A 1 4  DG 4  4  4  DG DG A . n 
A 1 5  DT 5  5  5  DT DT A . n 
A 1 6  DG 6  6  6  DG DG A . n 
A 1 7  DG 7  7  7  DG DG A . n 
A 1 8  DT 8  8  8  DT DT A . n 
A 1 9  DC 9  9  9  DC DC A . n 
A 1 10 DT 10 10 10 DT DT A . n 
A 1 11 DA 11 11 11 DA DA A . n 
A 1 12 DT 12 12 12 DT DT A . n 
A 1 13 DT 13 13 13 DT DT A . n 
A 1 14 DC 14 14 14 DC DC A . n 
A 1 15 DA 15 15 15 DA DA A . n 
A 1 16 DT 16 16 16 DT DT A . n 
A 1 17 DA 17 17 17 DA DA A . n 
A 1 18 DG 18 18 18 DG DG A . n 
A 1 19 DG 19 19 19 DG DG A . n 
A 1 20 DC 20 20 20 DC DC A . n 
A 1 21 DG 21 21 21 DG DG A . n 
A 1 22 DT 22 22 22 DT DT A . n 
A 1 23 DC 23 23 23 DC DC A . n 
A 1 24 DC 24 24 24 DC DC A . n 
A 1 25 DG 25 25 25 DG DG A . n 
A 1 26 DC 26 26 26 DC DC A . n 
A 1 27 DC 27 27 27 DC DC A . n 
A 1 28 DG 28 28 28 DG DG A . n 
A 1 29 DC 29 29 29 DC DC A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        I7U 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   I7U 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 I7U 1  101 101 I7U 3IV A . 
C 3 NA  1  102 1   NA  NA  A . 
D 3 NA  1  103 2   NA  NA  A . 
E 3 NA  1  104 3   NA  NA  A . 
F 3 NA  1  105 4   NA  NA  A . 
G 4 HOH 1  201 35  HOH HOH A . 
G 4 HOH 2  202 2   HOH HOH A . 
G 4 HOH 3  203 44  HOH HOH A . 
G 4 HOH 4  204 29  HOH HOH A . 
G 4 HOH 5  205 51  HOH HOH A . 
G 4 HOH 6  206 47  HOH HOH A . 
G 4 HOH 7  207 5   HOH HOH A . 
G 4 HOH 8  208 25  HOH HOH A . 
G 4 HOH 9  209 8   HOH HOH A . 
G 4 HOH 10 210 53  HOH HOH A . 
G 4 HOH 11 211 3   HOH HOH A . 
G 4 HOH 12 212 18  HOH HOH A . 
G 4 HOH 13 213 6   HOH HOH A . 
G 4 HOH 14 214 22  HOH HOH A . 
G 4 HOH 15 215 28  HOH HOH A . 
G 4 HOH 16 216 1   HOH HOH A . 
G 4 HOH 17 217 23  HOH HOH A . 
G 4 HOH 18 218 11  HOH HOH A . 
G 4 HOH 19 219 14  HOH HOH A . 
G 4 HOH 20 220 15  HOH HOH A . 
G 4 HOH 21 221 10  HOH HOH A . 
G 4 HOH 22 222 4   HOH HOH A . 
G 4 HOH 23 223 31  HOH HOH A . 
G 4 HOH 24 224 19  HOH HOH A . 
G 4 HOH 25 225 27  HOH HOH A . 
G 4 HOH 26 226 7   HOH HOH A . 
G 4 HOH 27 227 20  HOH HOH A . 
G 4 HOH 28 228 13  HOH HOH A . 
G 4 HOH 29 229 34  HOH HOH A . 
G 4 HOH 30 230 37  HOH HOH A . 
G 4 HOH 31 231 24  HOH HOH A . 
G 4 HOH 32 232 50  HOH HOH A . 
G 4 HOH 33 233 30  HOH HOH A . 
G 4 HOH 34 234 46  HOH HOH A . 
G 4 HOH 35 235 16  HOH HOH A . 
G 4 HOH 36 236 12  HOH HOH A . 
G 4 HOH 37 237 39  HOH HOH A . 
G 4 HOH 38 238 17  HOH HOH A . 
G 4 HOH 39 239 9   HOH HOH A . 
G 4 HOH 40 240 41  HOH HOH A . 
G 4 HOH 41 241 38  HOH HOH A . 
G 4 HOH 42 242 33  HOH HOH A . 
G 4 HOH 43 243 45  HOH HOH A . 
G 4 HOH 44 244 52  HOH HOH A . 
G 4 HOH 45 245 21  HOH HOH A . 
G 4 HOH 46 246 26  HOH HOH A . 
G 4 HOH 47 247 40  HOH HOH A . 
G 4 HOH 48 248 48  HOH HOH A . 
G 4 HOH 49 249 36  HOH HOH A . 
G 4 HOH 50 250 32  HOH HOH A . 
G 4 HOH 51 251 43  HOH HOH A . 
G 4 HOH 52 252 49  HOH HOH A . 
G 4 HOH 53 253 42  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8K0V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     49.292 
_cell.length_a_esd                 ? 
_cell.length_b                     49.292 
_cell.length_b_esd                 ? 
_cell.length_c                     50.960 
_cell.length_c_esd                 ? 
_cell.volume                       107228.282 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8K0V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8K0V 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.00 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          38.62 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;0.2 M Calcium chloride dihydrate
24% v/v Polyethylene glycol 400
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 X 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-03-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979183 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL02U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979183 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL02U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          19.25 
_reflns.entry_id                                       8K0V 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.67 
_reflns.d_resolution_low                               50.96 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     8671 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                17.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.500 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.67 
_reflns_shell.d_res_low                                     1.71 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             640 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.954 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               31.99 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8K0V 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.67 
_refine.ls_d_res_low                             42.69 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     8503 
_refine.ls_number_reflns_R_free                  469 
_refine.ls_number_reflns_R_work                  8034 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.28 
_refine.ls_percent_reflns_R_free                 5.52 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2415 
_refine.ls_R_factor_R_free                       0.2465 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2412 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 36.0781 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2559 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.67 
_refine_hist.d_res_low                        42.69 
_refine_hist.number_atoms_solvent             53 
_refine_hist.number_atoms_total               660 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        0 
_refine_hist.pdbx_number_atoms_nucleic_acid   591 
_refine_hist.pdbx_number_atoms_ligand         16 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0140  ? 674  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.5121  ? 1038 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0831  ? 115  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0116  ? 30   ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 32.6284 ? 286  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.67 1.91  . . 113 2581 95.23 . . . . 0.4397 . . . . . . . . . . . 0.4699 
'X-RAY DIFFRACTION' 1.91 2.41  . . 180 2663 99.82 . . . . 0.2819 . . . . . . . . . . . 0.3270 
'X-RAY DIFFRACTION' 2.41 42.69 . . 176 2790 99.70 . . . . 0.1944 . . . . . . . . . . . 0.1969 
# 
_struct.entry_id                     8K0V 
_struct.title                        'Crystal structure of theophylline DNA aptamer bound to 3-methylxanthine' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8K0V 
_struct_keywords.text            'Aptamer, Theophylline, 3-methylxanthine, DNA' 
_struct_keywords.pdbx_keywords   DNA 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    8K0V 
_struct_ref.pdbx_db_accession          8K0V 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8K0V 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 29 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             8K0V 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  29 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       29 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 160  ? 
1 MORE         -10  ? 
1 'SSA (A^2)'  4830 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A DG 4  O6  ? ? ? 1_555 C NA  .  NA ? ? A DG 4   A NA  102 1_555 ? ? ? ? ? ? ?            2.758 ? ? 
metalc2  metalc ? ? A DA 17 OP1 ? ? ? 1_555 E NA  .  NA ? ? A DA 17  A NA  104 3_655 ? ? ? ? ? ? ?            2.186 ? ? 
metalc3  metalc ? ? A DG 21 OP1 ? ? ? 1_555 E NA  .  NA ? ? A DG 21  A NA  104 1_555 ? ? ? ? ? ? ?            2.203 ? ? 
metalc4  metalc ? ? A DT 22 OP2 ? ? ? 1_555 E NA  .  NA ? ? A DT 22  A NA  104 1_555 ? ? ? ? ? ? ?            2.170 ? ? 
metalc5  metalc ? ? C NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 102 A HOH 210 6_554 ? ? ? ? ? ? ?            1.938 ? ? 
metalc6  metalc ? ? C NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 102 A HOH 238 1_555 ? ? ? ? ? ? ?            2.699 ? ? 
metalc7  metalc ? ? C NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 102 A HOH 241 1_555 ? ? ? ? ? ? ?            2.177 ? ? 
metalc8  metalc ? ? D NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 103 A HOH 204 4_655 ? ? ? ? ? ? ?            2.472 ? ? 
metalc9  metalc ? ? D NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 103 A HOH 240 1_555 ? ? ? ? ? ? ?            2.543 ? ? 
metalc10 metalc ? ? E NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 104 A HOH 216 2_544 ? ? ? ? ? ? ?            2.271 ? ? 
metalc11 metalc ? ? E NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 104 A HOH 219 2_544 ? ? ? ? ? ? ?            2.346 ? ? 
metalc12 metalc ? ? E NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 104 A HOH 245 1_555 ? ? ? ? ? ? ?            2.482 ? ? 
metalc13 metalc ? ? F NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 105 A HOH 207 1_555 ? ? ? ? ? ? ?            2.555 ? ? 
metalc14 metalc ? ? F NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 105 A HOH 221 1_555 ? ? ? ? ? ? ?            2.684 ? ? 
metalc15 metalc ? ? F NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 105 A HOH 222 1_555 ? ? ? ? ? ? ?            2.393 ? ? 
metalc16 metalc ? ? F NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 105 A HOH 231 1_555 ? ? ? ? ? ? ?            2.596 ? ? 
metalc17 metalc ? ? F NA .  NA  ? ? ? 1_555 G HOH .  O  ? ? A NA 105 A HOH 248 1_555 ? ? ? ? ? ? ?            2.138 ? ? 
hydrog1  hydrog ? ? A DG 1  N1  ? ? ? 1_555 A DC  29 N3 ? ? A DG 1   A DC  29  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog2  hydrog ? ? A DG 1  N2  ? ? ? 1_555 A DC  29 O2 ? ? A DG 1   A DC  29  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog3  hydrog ? ? A DG 1  O6  ? ? ? 1_555 A DC  29 N4 ? ? A DG 1   A DC  29  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog4  hydrog ? ? A DC 2  N3  ? ? ? 1_555 A DG  28 N1 ? ? A DC 2   A DG  28  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog5  hydrog ? ? A DC 2  N4  ? ? ? 1_555 A DG  28 O6 ? ? A DC 2   A DG  28  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog6  hydrog ? ? A DC 2  O2  ? ? ? 1_555 A DG  28 N2 ? ? A DC 2   A DG  28  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog7  hydrog ? ? A DG 3  N1  ? ? ? 1_555 A DC  27 N3 ? ? A DG 3   A DC  27  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog8  hydrog ? ? A DG 3  N2  ? ? ? 1_555 A DC  27 O2 ? ? A DG 3   A DC  27  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog9  hydrog ? ? A DG 3  O6  ? ? ? 1_555 A DC  27 N4 ? ? A DG 3   A DC  27  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog10 hydrog ? ? A DG 4  N1  ? ? ? 1_555 A DC  26 N3 ? ? A DG 4   A DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog11 hydrog ? ? A DG 4  N2  ? ? ? 1_555 A DC  26 O2 ? ? A DG 4   A DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog12 hydrog ? ? A DG 4  O6  ? ? ? 1_555 A DC  26 N4 ? ? A DG 4   A DC  26  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog13 hydrog ? ? A DT 5  N3  ? ? ? 1_555 A DG  25 O6 ? ? A DT 5   A DG  25  1_555 ? ? ? ? ? ? TYPE_28_PAIR ?     ? ? 
hydrog14 hydrog ? ? A DT 5  O2  ? ? ? 1_555 A DG  25 N1 ? ? A DT 5   A DG  25  1_555 ? ? ? ? ? ? TYPE_28_PAIR ?     ? ? 
hydrog15 hydrog ? ? A DG 6  N7  ? ? ? 1_555 A DG  19 N1 ? ? A DG 6   A DG  19  1_555 ? ? ? ? ? ? TYPE_7_PAIR  ?     ? ? 
hydrog16 hydrog ? ? A DG 6  O6  ? ? ? 1_555 A DG  19 N2 ? ? A DG 6   A DG  19  1_555 ? ? ? ? ? ? TYPE_7_PAIR  ?     ? ? 
hydrog17 hydrog ? ? A DG 6  N1  ? ? ? 1_555 A DC  24 N3 ? ? A DG 6   A DC  24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog18 hydrog ? ? A DG 6  N2  ? ? ? 1_555 A DC  24 O2 ? ? A DG 6   A DC  24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog19 hydrog ? ? A DG 6  O6  ? ? ? 1_555 A DC  24 N4 ? ? A DG 6   A DC  24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog20 hydrog ? ? A DG 7  N7  ? ? ? 1_555 A DG  18 N1 ? ? A DG 7   A DG  18  1_555 ? ? ? ? ? ? TYPE_7_PAIR  ?     ? ? 
hydrog21 hydrog ? ? A DG 7  O6  ? ? ? 1_555 A DG  18 N2 ? ? A DG 7   A DG  18  1_555 ? ? ? ? ? ? TYPE_7_PAIR  ?     ? ? 
hydrog22 hydrog ? ? A DG 7  N1  ? ? ? 1_555 A DC  23 N3 ? ? A DG 7   A DC  23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog23 hydrog ? ? A DG 7  N2  ? ? ? 1_555 A DC  23 O2 ? ? A DG 7   A DC  23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog24 hydrog ? ? A DG 7  O6  ? ? ? 1_555 A DC  23 N4 ? ? A DG 7   A DC  23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog25 hydrog ? ? A DC 9  N3  ? ? ? 1_555 A DG  21 N1 ? ? A DC 9   A DG  21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog26 hydrog ? ? A DC 9  N4  ? ? ? 1_555 A DG  21 O6 ? ? A DC 9   A DG  21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog27 hydrog ? ? A DC 9  O2  ? ? ? 1_555 A DG  21 N2 ? ? A DC 9   A DG  21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog28 hydrog ? ? A DA 11 N1  ? ? ? 1_555 A DT  16 N3 ? ? A DA 11  A DT  16  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog29 hydrog ? ? A DA 11 N6  ? ? ? 1_555 A DT  16 O4 ? ? A DA 11  A DT  16  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog30 hydrog ? ? A DT 12 N3  ? ? ? 1_555 A DA  15 N7 ? ? A DT 12  A DA  15  1_555 ? ? ? ? ? ? HOOGSTEEN    ?     ? ? 
hydrog31 hydrog ? ? A DT 12 O4  ? ? ? 1_555 A DA  15 N6 ? ? A DT 12  A DA  15  1_555 ? ? ? ? ? ? HOOGSTEEN    ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  O6  ? A DG  4  ? A DG  4   ? 1_555 NA ? C NA . ? A NA 102 ? 1_555 O   ? G HOH .  ? A HOH 210 ? 6_554 158.7 ? 
2  O6  ? A DG  4  ? A DG  4   ? 1_555 NA ? C NA . ? A NA 102 ? 1_555 O   ? G HOH .  ? A HOH 238 ? 1_555 80.8  ? 
3  O   ? G HOH .  ? A HOH 210 ? 6_554 NA ? C NA . ? A NA 102 ? 1_555 O   ? G HOH .  ? A HOH 238 ? 1_555 119.4 ? 
4  O6  ? A DG  4  ? A DG  4   ? 1_555 NA ? C NA . ? A NA 102 ? 1_555 O   ? G HOH .  ? A HOH 241 ? 1_555 83.7  ? 
5  O   ? G HOH .  ? A HOH 210 ? 6_554 NA ? C NA . ? A NA 102 ? 1_555 O   ? G HOH .  ? A HOH 241 ? 1_555 81.8  ? 
6  O   ? G HOH .  ? A HOH 238 ? 1_555 NA ? C NA . ? A NA 102 ? 1_555 O   ? G HOH .  ? A HOH 241 ? 1_555 113.5 ? 
7  OP1 ? A DA  17 ? A DA  17  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 OP1 ? A DG  21 ? A DG  21  ? 1_555 71.0  ? 
8  OP1 ? A DA  17 ? A DA  17  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 OP2 ? A DT  22 ? A DT  22  ? 1_555 66.4  ? 
9  OP1 ? A DG  21 ? A DG  21  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 OP2 ? A DT  22 ? A DT  22  ? 1_555 4.9   ? 
10 OP1 ? A DA  17 ? A DA  17  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 216 ? 2_544 76.5  ? 
11 OP1 ? A DG  21 ? A DG  21  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 216 ? 2_544 7.6   ? 
12 OP2 ? A DT  22 ? A DT  22  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 216 ? 2_544 12.3  ? 
13 OP1 ? A DA  17 ? A DA  17  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 219 ? 2_544 70.8  ? 
14 OP1 ? A DG  21 ? A DG  21  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 219 ? 2_544 2.5   ? 
15 OP2 ? A DT  22 ? A DT  22  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 219 ? 2_544 6.2   ? 
16 O   ? G HOH .  ? A HOH 216 ? 2_544 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 219 ? 2_544 6.3   ? 
17 OP1 ? A DA  17 ? A DA  17  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 245 ? 1_555 67.8  ? 
18 OP1 ? A DG  21 ? A DG  21  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 245 ? 1_555 8.0   ? 
19 OP2 ? A DT  22 ? A DT  22  ? 1_555 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 245 ? 1_555 9.1   ? 
20 O   ? G HOH .  ? A HOH 216 ? 2_544 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 245 ? 1_555 8.9   ? 
21 O   ? G HOH .  ? A HOH 219 ? 2_544 NA ? E NA . ? A NA 104 ? 3_655 O   ? G HOH .  ? A HOH 245 ? 1_555 5.7   ? 
22 O   ? G HOH .  ? A HOH 204 ? 4_655 NA ? D NA . ? A NA 103 ? 1_555 O   ? G HOH .  ? A HOH 240 ? 1_555 149.0 ? 
23 O   ? G HOH .  ? A HOH 207 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 221 ? 1_555 94.5  ? 
24 O   ? G HOH .  ? A HOH 207 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 222 ? 1_555 86.8  ? 
25 O   ? G HOH .  ? A HOH 221 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 222 ? 1_555 67.9  ? 
26 O   ? G HOH .  ? A HOH 207 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 231 ? 1_555 150.3 ? 
27 O   ? G HOH .  ? A HOH 221 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 231 ? 1_555 109.5 ? 
28 O   ? G HOH .  ? A HOH 222 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 231 ? 1_555 86.3  ? 
29 O   ? G HOH .  ? A HOH 207 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 248 ? 1_555 135.2 ? 
30 O   ? G HOH .  ? A HOH 221 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 248 ? 1_555 115.8 ? 
31 O   ? G HOH .  ? A HOH 222 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 248 ? 1_555 133.8 ? 
32 O   ? G HOH .  ? A HOH 231 ? 1_555 NA ? F NA . ? A NA 105 ? 1_555 O   ? G HOH .  ? A HOH 248 ? 1_555 48.0  ? 
# 
_pdbx_entry_details.entry_id                   8K0V 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O6    A DG  1   ? ? H42 A DC  29  ? ? 1.58 
2 1 O     A HOH 231 ? ? O   A HOH 248 ? ? 1.97 
3 1 "O3'" A DC  26  ? ? O   A HOH 201 ? ? 2.15 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     202 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    A 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     227 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   2_544 
_pdbx_validate_symm_contact.dist              1.93 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 "O3'" A DG 6  ? ? "C3'" A DG 6  ? ? 1.378 1.419 -0.041 0.006 N 
2 1 "O3'" A DT 10 ? ? "C3'" A DT 10 ? ? 1.367 1.419 -0.052 0.006 N 
3 1 "O3'" A DC 14 ? ? "C3'" A DC 14 ? ? 1.379 1.419 -0.040 0.006 N 
4 1 "O3'" A DT 22 ? ? "C3'" A DT 22 ? ? 1.378 1.419 -0.041 0.006 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 "O4'" A DG 7  ? ? "C1'" A DG 7  ? ? N9 A DG 7  ? ? 110.69 108.30 2.39 0.30 N 
2 1 "O4'" A DG 18 ? ? "C1'" A DG 18 ? ? N9 A DG 18 ? ? 110.46 108.30 2.16 0.30 N 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     208 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   G 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined 16.710807743  -6.07242343437 -10.6409186303 0.410567235064 ? -0.0875744909797 ? 0.068735821723  ? 
0.44014659052  ? 0.0840377380659 ? 0.310320566805 ? 4.7512813531  ? -0.490872530273 ? -1.81177920212 ? 4.62557411845 ? 
-1.70634410925 ? 3.95495235182 ? 0.149639705206 ? -0.603366627872 ? -0.623631555372  ? -0.504227882043 ? 0.477533629514  ? 
-0.0768259274331 ? -0.116327798479  ? -0.272656112879   ? -0.526655309606 ? 
2 'X-RAY DIFFRACTION' ? refined 15.718589448  -13.8370268487 7.69009579045  0.202848019237 ? -0.0313718820489 ? 0.0107778731316 ? 
0.182084126524 ? 0.026545296232  ? 0.185349063333 ? 7.00351140288 ? 1.63326336998   ? 0.394512701148 ? 2.66452726435 ? 
0.854868901602 ? 4.74565553407 ? 0.285049016766 ? -0.257068806392 ? -0.0274821857956 ? 0.33680313389   ? -0.145614614543 ? 
0.033868694419   ? -0.0116999558305 ? -0.00418052398987 ? -0.154272482412 ? 
3 'X-RAY DIFFRACTION' ? refined 11.4898371129 -8.58757424477 -5.30867292392 0.229496940179 ? 0.0213688447542  ? 0.023893450028  ? 
0.268281927508 ? 0.0126379625626 ? 0.204062560857 ? 4.56092730436 ? 1.90559071372   ? -1.10994144253 ? 7.17430294286 ? 
-4.00546085683 ? 5.66651494596 ? 0.247858567554 ? 0.18220375851   ? 0.365945521768   ? 0.0362800625929 ? 0.340394865056  ? 
1.06748989988    ? -0.49047007489   ? -0.218051161748   ? -0.531197350694 ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 A ? A 1  ? A ? A 5  ? ? 
;chain 'A' and (resid 1 through 5 )
;
2 'X-RAY DIFFRACTION' 2 A ? A 6  ? A ? A 20 ? ? 
;chain 'A' and (resid 6 through 20 )
;
3 'X-RAY DIFFRACTION' 3 A ? A 21 ? A ? A 29 ? ? 
;chain 'A' and (resid 21 through 29 )
;
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
DA  OP3    O  N N 1   
DA  P      P  N N 2   
DA  OP1    O  N N 3   
DA  OP2    O  N N 4   
DA  "O5'"  O  N N 5   
DA  "C5'"  C  N N 6   
DA  "C4'"  C  N R 7   
DA  "O4'"  O  N N 8   
DA  "C3'"  C  N S 9   
DA  "O3'"  O  N N 10  
DA  "C2'"  C  N N 11  
DA  "C1'"  C  N R 12  
DA  N9     N  Y N 13  
DA  C8     C  Y N 14  
DA  N7     N  Y N 15  
DA  C5     C  Y N 16  
DA  C6     C  Y N 17  
DA  N6     N  N N 18  
DA  N1     N  Y N 19  
DA  C2     C  Y N 20  
DA  N3     N  Y N 21  
DA  C4     C  Y N 22  
DA  HOP3   H  N N 23  
DA  HOP2   H  N N 24  
DA  "H5'"  H  N N 25  
DA  "H5''" H  N N 26  
DA  "H4'"  H  N N 27  
DA  "H3'"  H  N N 28  
DA  "HO3'" H  N N 29  
DA  "H2'"  H  N N 30  
DA  "H2''" H  N N 31  
DA  "H1'"  H  N N 32  
DA  H8     H  N N 33  
DA  H61    H  N N 34  
DA  H62    H  N N 35  
DA  H2     H  N N 36  
DC  OP3    O  N N 37  
DC  P      P  N N 38  
DC  OP1    O  N N 39  
DC  OP2    O  N N 40  
DC  "O5'"  O  N N 41  
DC  "C5'"  C  N N 42  
DC  "C4'"  C  N R 43  
DC  "O4'"  O  N N 44  
DC  "C3'"  C  N S 45  
DC  "O3'"  O  N N 46  
DC  "C2'"  C  N N 47  
DC  "C1'"  C  N R 48  
DC  N1     N  N N 49  
DC  C2     C  N N 50  
DC  O2     O  N N 51  
DC  N3     N  N N 52  
DC  C4     C  N N 53  
DC  N4     N  N N 54  
DC  C5     C  N N 55  
DC  C6     C  N N 56  
DC  HOP3   H  N N 57  
DC  HOP2   H  N N 58  
DC  "H5'"  H  N N 59  
DC  "H5''" H  N N 60  
DC  "H4'"  H  N N 61  
DC  "H3'"  H  N N 62  
DC  "HO3'" H  N N 63  
DC  "H2'"  H  N N 64  
DC  "H2''" H  N N 65  
DC  "H1'"  H  N N 66  
DC  H41    H  N N 67  
DC  H42    H  N N 68  
DC  H5     H  N N 69  
DC  H6     H  N N 70  
DG  OP3    O  N N 71  
DG  P      P  N N 72  
DG  OP1    O  N N 73  
DG  OP2    O  N N 74  
DG  "O5'"  O  N N 75  
DG  "C5'"  C  N N 76  
DG  "C4'"  C  N R 77  
DG  "O4'"  O  N N 78  
DG  "C3'"  C  N S 79  
DG  "O3'"  O  N N 80  
DG  "C2'"  C  N N 81  
DG  "C1'"  C  N R 82  
DG  N9     N  Y N 83  
DG  C8     C  Y N 84  
DG  N7     N  Y N 85  
DG  C5     C  Y N 86  
DG  C6     C  N N 87  
DG  O6     O  N N 88  
DG  N1     N  N N 89  
DG  C2     C  N N 90  
DG  N2     N  N N 91  
DG  N3     N  N N 92  
DG  C4     C  Y N 93  
DG  HOP3   H  N N 94  
DG  HOP2   H  N N 95  
DG  "H5'"  H  N N 96  
DG  "H5''" H  N N 97  
DG  "H4'"  H  N N 98  
DG  "H3'"  H  N N 99  
DG  "HO3'" H  N N 100 
DG  "H2'"  H  N N 101 
DG  "H2''" H  N N 102 
DG  "H1'"  H  N N 103 
DG  H8     H  N N 104 
DG  H1     H  N N 105 
DG  H21    H  N N 106 
DG  H22    H  N N 107 
DT  OP3    O  N N 108 
DT  P      P  N N 109 
DT  OP1    O  N N 110 
DT  OP2    O  N N 111 
DT  "O5'"  O  N N 112 
DT  "C5'"  C  N N 113 
DT  "C4'"  C  N R 114 
DT  "O4'"  O  N N 115 
DT  "C3'"  C  N S 116 
DT  "O3'"  O  N N 117 
DT  "C2'"  C  N N 118 
DT  "C1'"  C  N R 119 
DT  N1     N  N N 120 
DT  C2     C  N N 121 
DT  O2     O  N N 122 
DT  N3     N  N N 123 
DT  C4     C  N N 124 
DT  O4     O  N N 125 
DT  C5     C  N N 126 
DT  C7     C  N N 127 
DT  C6     C  N N 128 
DT  HOP3   H  N N 129 
DT  HOP2   H  N N 130 
DT  "H5'"  H  N N 131 
DT  "H5''" H  N N 132 
DT  "H4'"  H  N N 133 
DT  "H3'"  H  N N 134 
DT  "HO3'" H  N N 135 
DT  "H2'"  H  N N 136 
DT  "H2''" H  N N 137 
DT  "H1'"  H  N N 138 
DT  H3     H  N N 139 
DT  H71    H  N N 140 
DT  H72    H  N N 141 
DT  H73    H  N N 142 
DT  H6     H  N N 143 
HOH O      O  N N 144 
HOH H1     H  N N 145 
HOH H2     H  N N 146 
I7U C11    C  Y N 147 
I7U C01    C  N N 148 
I7U C03    C  Y N 149 
I7U C04    C  Y N 150 
I7U C05    C  N N 151 
I7U C08    C  N N 152 
I7U N02    N  N N 153 
I7U N07    N  N N 154 
I7U N10    N  Y N 155 
I7U N12    N  Y N 156 
I7U O06    O  N N 157 
I7U O09    O  N N 158 
I7U H111   H  N N 159 
I7U H013   H  N N 160 
I7U H012   H  N N 161 
I7U H011   H  N N 162 
I7U H071   H  N N 163 
I7U H101   H  N N 164 
NA  NA     NA N N 165 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
DA  OP3   P      sing N N 1   
DA  OP3   HOP3   sing N N 2   
DA  P     OP1    doub N N 3   
DA  P     OP2    sing N N 4   
DA  P     "O5'"  sing N N 5   
DA  OP2   HOP2   sing N N 6   
DA  "O5'" "C5'"  sing N N 7   
DA  "C5'" "C4'"  sing N N 8   
DA  "C5'" "H5'"  sing N N 9   
DA  "C5'" "H5''" sing N N 10  
DA  "C4'" "O4'"  sing N N 11  
DA  "C4'" "C3'"  sing N N 12  
DA  "C4'" "H4'"  sing N N 13  
DA  "O4'" "C1'"  sing N N 14  
DA  "C3'" "O3'"  sing N N 15  
DA  "C3'" "C2'"  sing N N 16  
DA  "C3'" "H3'"  sing N N 17  
DA  "O3'" "HO3'" sing N N 18  
DA  "C2'" "C1'"  sing N N 19  
DA  "C2'" "H2'"  sing N N 20  
DA  "C2'" "H2''" sing N N 21  
DA  "C1'" N9     sing N N 22  
DA  "C1'" "H1'"  sing N N 23  
DA  N9    C8     sing Y N 24  
DA  N9    C4     sing Y N 25  
DA  C8    N7     doub Y N 26  
DA  C8    H8     sing N N 27  
DA  N7    C5     sing Y N 28  
DA  C5    C6     sing Y N 29  
DA  C5    C4     doub Y N 30  
DA  C6    N6     sing N N 31  
DA  C6    N1     doub Y N 32  
DA  N6    H61    sing N N 33  
DA  N6    H62    sing N N 34  
DA  N1    C2     sing Y N 35  
DA  C2    N3     doub Y N 36  
DA  C2    H2     sing N N 37  
DA  N3    C4     sing Y N 38  
DC  OP3   P      sing N N 39  
DC  OP3   HOP3   sing N N 40  
DC  P     OP1    doub N N 41  
DC  P     OP2    sing N N 42  
DC  P     "O5'"  sing N N 43  
DC  OP2   HOP2   sing N N 44  
DC  "O5'" "C5'"  sing N N 45  
DC  "C5'" "C4'"  sing N N 46  
DC  "C5'" "H5'"  sing N N 47  
DC  "C5'" "H5''" sing N N 48  
DC  "C4'" "O4'"  sing N N 49  
DC  "C4'" "C3'"  sing N N 50  
DC  "C4'" "H4'"  sing N N 51  
DC  "O4'" "C1'"  sing N N 52  
DC  "C3'" "O3'"  sing N N 53  
DC  "C3'" "C2'"  sing N N 54  
DC  "C3'" "H3'"  sing N N 55  
DC  "O3'" "HO3'" sing N N 56  
DC  "C2'" "C1'"  sing N N 57  
DC  "C2'" "H2'"  sing N N 58  
DC  "C2'" "H2''" sing N N 59  
DC  "C1'" N1     sing N N 60  
DC  "C1'" "H1'"  sing N N 61  
DC  N1    C2     sing N N 62  
DC  N1    C6     sing N N 63  
DC  C2    O2     doub N N 64  
DC  C2    N3     sing N N 65  
DC  N3    C4     doub N N 66  
DC  C4    N4     sing N N 67  
DC  C4    C5     sing N N 68  
DC  N4    H41    sing N N 69  
DC  N4    H42    sing N N 70  
DC  C5    C6     doub N N 71  
DC  C5    H5     sing N N 72  
DC  C6    H6     sing N N 73  
DG  OP3   P      sing N N 74  
DG  OP3   HOP3   sing N N 75  
DG  P     OP1    doub N N 76  
DG  P     OP2    sing N N 77  
DG  P     "O5'"  sing N N 78  
DG  OP2   HOP2   sing N N 79  
DG  "O5'" "C5'"  sing N N 80  
DG  "C5'" "C4'"  sing N N 81  
DG  "C5'" "H5'"  sing N N 82  
DG  "C5'" "H5''" sing N N 83  
DG  "C4'" "O4'"  sing N N 84  
DG  "C4'" "C3'"  sing N N 85  
DG  "C4'" "H4'"  sing N N 86  
DG  "O4'" "C1'"  sing N N 87  
DG  "C3'" "O3'"  sing N N 88  
DG  "C3'" "C2'"  sing N N 89  
DG  "C3'" "H3'"  sing N N 90  
DG  "O3'" "HO3'" sing N N 91  
DG  "C2'" "C1'"  sing N N 92  
DG  "C2'" "H2'"  sing N N 93  
DG  "C2'" "H2''" sing N N 94  
DG  "C1'" N9     sing N N 95  
DG  "C1'" "H1'"  sing N N 96  
DG  N9    C8     sing Y N 97  
DG  N9    C4     sing Y N 98  
DG  C8    N7     doub Y N 99  
DG  C8    H8     sing N N 100 
DG  N7    C5     sing Y N 101 
DG  C5    C6     sing N N 102 
DG  C5    C4     doub Y N 103 
DG  C6    O6     doub N N 104 
DG  C6    N1     sing N N 105 
DG  N1    C2     sing N N 106 
DG  N1    H1     sing N N 107 
DG  C2    N2     sing N N 108 
DG  C2    N3     doub N N 109 
DG  N2    H21    sing N N 110 
DG  N2    H22    sing N N 111 
DG  N3    C4     sing N N 112 
DT  OP3   P      sing N N 113 
DT  OP3   HOP3   sing N N 114 
DT  P     OP1    doub N N 115 
DT  P     OP2    sing N N 116 
DT  P     "O5'"  sing N N 117 
DT  OP2   HOP2   sing N N 118 
DT  "O5'" "C5'"  sing N N 119 
DT  "C5'" "C4'"  sing N N 120 
DT  "C5'" "H5'"  sing N N 121 
DT  "C5'" "H5''" sing N N 122 
DT  "C4'" "O4'"  sing N N 123 
DT  "C4'" "C3'"  sing N N 124 
DT  "C4'" "H4'"  sing N N 125 
DT  "O4'" "C1'"  sing N N 126 
DT  "C3'" "O3'"  sing N N 127 
DT  "C3'" "C2'"  sing N N 128 
DT  "C3'" "H3'"  sing N N 129 
DT  "O3'" "HO3'" sing N N 130 
DT  "C2'" "C1'"  sing N N 131 
DT  "C2'" "H2'"  sing N N 132 
DT  "C2'" "H2''" sing N N 133 
DT  "C1'" N1     sing N N 134 
DT  "C1'" "H1'"  sing N N 135 
DT  N1    C2     sing N N 136 
DT  N1    C6     sing N N 137 
DT  C2    O2     doub N N 138 
DT  C2    N3     sing N N 139 
DT  N3    C4     sing N N 140 
DT  N3    H3     sing N N 141 
DT  C4    O4     doub N N 142 
DT  C4    C5     sing N N 143 
DT  C5    C7     sing N N 144 
DT  C5    C6     doub N N 145 
DT  C7    H71    sing N N 146 
DT  C7    H72    sing N N 147 
DT  C7    H73    sing N N 148 
DT  C6    H6     sing N N 149 
HOH O     H1     sing N N 150 
HOH O     H2     sing N N 151 
I7U C01   N02    sing N N 152 
I7U C03   C04    doub Y N 153 
I7U C03   N02    sing N N 154 
I7U C03   N12    sing Y N 155 
I7U C04   C05    sing N N 156 
I7U C04   N10    sing Y N 157 
I7U C05   N07    sing N N 158 
I7U C05   O06    doub N N 159 
I7U C08   N02    sing N N 160 
I7U C08   N07    sing N N 161 
I7U C08   O09    doub N N 162 
I7U C11   N10    sing Y N 163 
I7U C11   N12    doub Y N 164 
I7U C11   H111   sing N N 165 
I7U C01   H013   sing N N 166 
I7U C01   H012   sing N N 167 
I7U C01   H011   sing N N 168 
I7U N07   H071   sing N N 169 
I7U N10   H101   sing N N 170 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
8K0V 'double helix'         
8K0V 'b-form double helix'  
8K0V 'hairpin loop'         
8K0V 'mismatched base pair' 
8K0V 'triple helix'         
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A DG 1  1_555 A DC 29 1_555 -0.090 -0.392 0.056  -2.598 -3.889  -5.103  1  A_DG1:DC29_A  A 1  ? A 29 ? 19 1 
1 A DC 2  1_555 A DG 28 1_555 0.123  -0.261 0.380  -7.247 -15.459 -1.142  2  A_DC2:DG28_A  A 2  ? A 28 ? 19 1 
1 A DG 3  1_555 A DC 27 1_555 -0.185 -0.245 0.335  3.299  -12.408 -2.103  3  A_DG3:DC27_A  A 3  ? A 27 ? 19 1 
1 A DG 4  1_555 A DC 26 1_555 0.162  -0.156 0.066  -3.697 -10.169 1.705   4  A_DG4:DC26_A  A 4  ? A 26 ? 19 1 
1 A DT 5  1_555 A DG 25 1_555 2.402  -0.740 0.274  -7.741 -8.771  -3.711  5  A_DT5:DG25_A  A 5  ? A 25 ? 28 1 
1 A DG 6  1_555 A DC 24 1_555 -0.288 -0.316 0.264  3.610  -9.960  0.684   6  A_DG6:DC24_A  A 6  ? A 24 ? 19 1 
1 A DG 7  1_555 A DC 23 1_555 -0.171 -0.246 0.304  3.782  -9.988  1.580   7  A_DG7:DC23_A  A 7  ? A 23 ? 19 1 
1 A DC 9  1_555 A DG 21 1_555 0.352  -0.271 0.333  8.374  -11.545 -1.196  8  A_DC9:DG21_A  A 9  ? A 21 ? 19 1 
1 A DA 11 1_555 A DT 16 1_555 0.001  -0.224 0.234  -7.212 -5.366  7.540   9  A_DA11:DT16_A A 11 ? A 16 ? 20 1 
1 A DT 12 1_555 A DA 15 1_555 -0.675 3.476  -0.528 10.629 -7.403  -68.548 10 A_DT12:DA15_A A 12 ? A 15 ? 23 3 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A DG 1  1_555 A DC 29 1_555 A DC 2  1_555 A DG 28 1_555 -0.268 0.081  3.331 -2.615 -4.677 36.885  0.760  0.066  3.307 -7.344 
4.106  37.259  1 AA_DG1DC2:DG28DC29_AA   A 1  ? A 29 ? A 2  ? A 28 ? 
1 A DC 2  1_555 A DG 28 1_555 A DG 3  1_555 A DC 27 1_555 -0.246 0.457  3.177 0.133  5.832  29.840  -0.279 0.496  3.206 11.191 
-0.255 30.392  2 AA_DC2DG3:DC27DG28_AA   A 2  ? A 28 ? A 3  ? A 27 ? 
1 A DG 3  1_555 A DC 27 1_555 A DG 4  1_555 A DC 26 1_555 0.397  -0.383 3.511 0.847  4.976  34.400  -1.452 -0.527 3.432 8.358  
-1.422 34.757  3 AA_DG3DG4:DC26DC27_AA   A 3  ? A 27 ? A 4  ? A 26 ? 
1 A DG 4  1_555 A DC 26 1_555 A DT 5  1_555 A DG 25 1_555 0.001  -0.581 3.452 -1.734 -2.869 38.724  -0.503 -0.226 3.481 -4.316 
2.610  38.864  4 AA_DG4DT5:DG25DC26_AA   A 4  ? A 26 ? A 5  ? A 25 ? 
1 A DT 5  1_555 A DG 25 1_555 A DG 6  1_555 A DC 24 1_555 -0.198 0.033  2.951 3.030  7.752  25.532  -1.731 1.132  2.798 16.974 
-6.636 26.833  5 AA_DT5DG6:DC24DG25_AA   A 5  ? A 25 ? A 6  ? A 24 ? 
1 A DG 6  1_555 A DC 24 1_555 A DG 7  1_555 A DC 23 1_555 0.385  -0.584 3.218 -2.175 6.233  29.728  -2.311 -1.151 3.001 11.964 
4.175  30.436  6 AA_DG6DG7:DC23DC24_AA   A 6  ? A 24 ? A 7  ? A 23 ? 
1 A DG 7  1_555 A DC 23 1_555 A DC 9  1_555 A DG 21 1_555 0.718  -1.783 6.185 0.242  5.321  66.508  -2.015 -0.635 6.046 4.844  
-0.221 66.697  7 AA_DG7DC9:DG21DC23_AA   A 7  ? A 23 ? A 9  ? A 21 ? 
1 A DC 9  1_555 A DG 21 1_555 A DA 11 1_555 A DT 16 1_555 5.742  -0.692 3.991 -3.307 -3.739 108.863 -0.369 -3.578 3.887 -2.298 
2.032  108.941 8 AA_DC9DA11:DT16DG21_AA  A 9  ? A 21 ? A 11 ? A 16 ? 
1 A DA 11 1_555 A DT 16 1_555 A DT 12 1_555 A DA 15 1_555 1.426  -1.865 2.925 5.122  2.180  74.031  -1.607 -1.037 2.957 1.808  
-4.248 74.210  9 AA_DA11DT12:DA15DT16_AA A 11 ? A 16 ? A 12 ? A 15 ? 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32171191 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8K0T 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    8K0V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   0.020287 
_atom_sites.fract_transf_matrix[1][2]   0.011713 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.023426 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.019623 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 9.38062 1.54875 ? ? 3.38349  72.32734 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1   O  "O5'"  . DG  A 1 1  ? 11.31826 -6.96192  -21.48684 1.000 59.98258 ? 1   DG  A "O5'"  1 
ATOM   2   C  "C5'"  . DG  A 1 1  ? 11.60618 -7.91888  -20.46976 1.000 51.66890 ? 1   DG  A "C5'"  1 
ATOM   3   C  "C4'"  . DG  A 1 1  ? 12.98077 -7.67450  -19.87833 1.000 43.62454 ? 1   DG  A "C4'"  1 
ATOM   4   O  "O4'"  . DG  A 1 1  ? 13.08300 -6.28365  -19.44864 1.000 48.02745 ? 1   DG  A "O4'"  1 
ATOM   5   C  "C3'"  . DG  A 1 1  ? 13.30367 -8.50543  -18.64613 1.000 38.99489 ? 1   DG  A "C3'"  1 
ATOM   6   O  "O3'"  . DG  A 1 1  ? 14.70017 -8.75174  -18.57062 1.000 51.00294 ? 1   DG  A "O3'"  1 
ATOM   7   C  "C2'"  . DG  A 1 1  ? 12.81701 -7.61096  -17.52936 1.000 44.04524 ? 1   DG  A "C2'"  1 
ATOM   8   C  "C1'"  . DG  A 1 1  ? 13.22140 -6.22635  -18.03581 1.000 42.75977 ? 1   DG  A "C1'"  1 
ATOM   9   N  N9     . DG  A 1 1  ? 12.40819 -5.11597  -17.49094 1.000 37.37958 ? 1   DG  A N9     1 
ATOM   10  C  C8     . DG  A 1 1  ? 11.03504 -5.03109  -17.44519 1.000 37.12719 ? 1   DG  A C8     1 
ATOM   11  N  N7     . DG  A 1 1  ? 10.59586 -3.91519  -16.89261 1.000 36.55567 ? 1   DG  A N7     1 
ATOM   12  C  C5     . DG  A 1 1  ? 11.75635 -3.21523  -16.54802 1.000 34.73763 ? 1   DG  A C5     1 
ATOM   13  C  C6     . DG  A 1 1  ? 11.92367 -1.94109  -15.91234 1.000 38.09502 ? 1   DG  A C6     1 
ATOM   14  O  O6     . DG  A 1 1  ? 11.05981 -1.15046  -15.49704 1.000 37.25255 ? 1   DG  A O6     1 
ATOM   15  N  N1     . DG  A 1 1  ? 13.25959 -1.61441  -15.76985 1.000 39.92080 ? 1   DG  A N1     1 
ATOM   16  C  C2     . DG  A 1 1  ? 14.30249 -2.39490  -16.17519 1.000 39.24049 ? 1   DG  A C2     1 
ATOM   17  N  N2     . DG  A 1 1  ? 15.51689 -1.91174  -15.92533 1.000 39.39531 ? 1   DG  A N2     1 
ATOM   18  N  N3     . DG  A 1 1  ? 14.17196 -3.58108  -16.75400 1.000 37.10990 ? 1   DG  A N3     1 
ATOM   19  C  C4     . DG  A 1 1  ? 12.87615 -3.92953  -16.91511 1.000 34.23484 ? 1   DG  A C4     1 
ATOM   20  H  "H5'"  . DG  A 1 1  ? 11.57523 -8.81040  -20.85071 1.000 62.06474 ? 1   DG  A "H5'"  1 
ATOM   21  H  "H5''" . DG  A 1 1  ? 10.93923 -7.85171  -19.76865 1.000 62.06474 ? 1   DG  A "H5''" 1 
ATOM   22  H  "H4'"  . DG  A 1 1  ? 13.65241 -7.84397  -20.55736 1.000 52.41151 ? 1   DG  A "H4'"  1 
ATOM   23  H  "H3'"  . DG  A 1 1  ? 12.81706 -9.34454  -18.65023 1.000 46.61568 ? 1   DG  A "H3'"  1 
ATOM   24  H  "H2'"  . DG  A 1 1  ? 11.85651 -7.67959  -17.41265 1.000 52.91635 ? 1   DG  A "H2'"  1 
ATOM   25  H  "H2''" . DG  A 1 1  ? 13.25316 -7.82290  -16.68926 1.000 52.91635 ? 1   DG  A "H2''" 1 
ATOM   26  H  "H1'"  . DG  A 1 1  ? 14.14831 -6.04791  -17.81244 1.000 51.37378 ? 1   DG  A "H1'"  1 
ATOM   27  H  H8     . DG  A 1 1  ? 10.47155 -5.69501  -17.77167 1.000 44.24233 ? 1   DG  A H8     1 
ATOM   28  H  H1     . DG  A 1 1  ? 13.44729 -0.86226  -15.39751 1.000 47.96702 ? 1   DG  A H1     1 
ATOM   29  H  H21    . DG  A 1 1  ? 16.21366 -2.36829  -16.13904 1.000 47.33643 ? 1   DG  A H21    1 
ATOM   30  H  H22    . DG  A 1 1  ? 15.60498 -1.14293  -15.55014 1.000 47.33643 ? 1   DG  A H22    1 
ATOM   31  H  "HO5'" . DG  A 1 1  ? 11.83408 -6.31047  -21.60997 1.000 72.04115 ? 1   DG  A "HO5'" 1 
ATOM   32  P  P      . DC  A 1 2  ? 15.29968 -10.12926 -17.97860 1.000 56.53132 ? 2   DC  A P      1 
ATOM   33  O  OP1    . DC  A 1 2  ? 15.88237 -10.94340 -19.08012 1.000 44.29908 ? 2   DC  A OP1    1 
ATOM   34  O  OP2    . DC  A 1 2  ? 14.32406 -10.71017 -17.01076 1.000 46.81064 ? 2   DC  A OP2    1 
ATOM   35  O  "O5'"  . DC  A 1 2  ? 16.56392 -9.61819  -17.16323 1.000 48.54082 ? 2   DC  A "O5'"  1 
ATOM   36  C  "C5'"  . DC  A 1 2  ? 17.38694 -8.62359  -17.71207 1.000 40.52413 ? 2   DC  A "C5'"  1 
ATOM   37  C  "C4'"  . DC  A 1 2  ? 17.77837 -7.61805  -16.66216 1.000 39.39274 ? 2   DC  A "C4'"  1 
ATOM   38  O  "O4'"  . DC  A 1 2  ? 16.72421 -6.64855  -16.47906 1.000 38.81853 ? 2   DC  A "O4'"  1 
ATOM   39  C  "C3'"  . DC  A 1 2  ? 17.99126 -8.20196  -15.28937 1.000 38.79504 ? 2   DC  A "C3'"  1 
ATOM   40  O  "O3'"  . DC  A 1 2  ? 19.29646 -8.67782  -15.15218 1.000 36.14717 ? 2   DC  A "O3'"  1 
ATOM   41  C  "C2'"  . DC  A 1 2  ? 17.68983 -7.03023  -14.34765 1.000 40.28099 ? 2   DC  A "C2'"  1 
ATOM   42  C  "C1'"  . DC  A 1 2  ? 16.88610 -6.04721  -15.20054 1.000 39.35786 ? 2   DC  A "C1'"  1 
ATOM   43  N  N1     . DC  A 1 2  ? 15.53452 -5.73771  -14.66096 1.000 37.90909 ? 2   DC  A N1     1 
ATOM   44  C  C2     . DC  A 1 2  ? 15.30115 -4.54064  -13.96419 1.000 32.90245 ? 2   DC  A C2     1 
ATOM   45  O  O2     . DC  A 1 2  ? 16.23729 -3.75557  -13.76704 1.000 34.62591 ? 2   DC  A O2     1 
ATOM   46  N  N3     . DC  A 1 2  ? 14.04794 -4.28166  -13.50945 1.000 36.85752 ? 2   DC  A N3     1 
ATOM   47  C  C4     . DC  A 1 2  ? 13.06470 -5.14942  -13.73821 1.000 36.41710 ? 2   DC  A C4     1 
ATOM   48  N  N4     . DC  A 1 2  ? 11.84706 -4.85677  -13.27618 1.000 33.11645 ? 2   DC  A N4     1 
ATOM   49  C  C5     . DC  A 1 2  ? 13.28628 -6.36840  -14.44697 1.000 40.02022 ? 2   DC  A C5     1 
ATOM   50  C  C6     . DC  A 1 2  ? 14.52291 -6.61952  -14.87605 1.000 32.98570 ? 2   DC  A C6     1 
ATOM   51  H  "H5'"  . DC  A 1 2  ? 16.91081 -8.17199  -18.42639 1.000 48.69102 ? 2   DC  A "H5'"  1 
ATOM   52  H  "H5''" . DC  A 1 2  ? 18.18669 -9.03445  -18.07606 1.000 48.69102 ? 2   DC  A "H5''" 1 
ATOM   53  H  "H4'"  . DC  A 1 2  ? 18.57914 -7.15928  -16.96082 1.000 47.33334 ? 2   DC  A "H4'"  1 
ATOM   54  H  "H3'"  . DC  A 1 2  ? 17.35546 -8.91746  -15.13213 1.000 46.61611 ? 2   DC  A "H3'"  1 
ATOM   55  H  "H2'"  . DC  A 1 2  ? 17.17143 -7.32706  -13.58341 1.000 48.39925 ? 2   DC  A "H2'"  1 
ATOM   56  H  "H2''" . DC  A 1 2  ? 18.51112 -6.62142  -14.03259 1.000 48.39925 ? 2   DC  A "H2''" 1 
ATOM   57  H  "H1'"  . DC  A 1 2  ? 17.39370 -5.22538  -15.28906 1.000 47.29150 ? 2   DC  A "H1'"  1 
ATOM   58  H  H41    . DC  A 1 2  ? 11.19418 -5.40025  -13.41025 1.000 39.42944 ? 2   DC  A H41    1 
ATOM   59  H  H42    . DC  A 1 2  ? 11.71544 -4.12474  -12.84443 1.000 39.42944 ? 2   DC  A H42    1 
ATOM   60  H  H5     . DC  A 1 2  ? 12.59181 -6.96671  -14.60393 1.000 48.08633 ? 2   DC  A H5     1 
ATOM   61  H  H6     . DC  A 1 2  ? 14.69662 -7.41204  -15.33061 1.000 39.64491 ? 2   DC  A H6     1 
ATOM   62  P  P      . DG  A 1 3  ? 19.67497 -9.50152  -13.84072 1.000 36.34632 ? 3   DG  A P      1 
ATOM   63  O  OP1    . DG  A 1 3  ? 20.83286 -10.37521 -14.12938 1.000 38.74148 ? 3   DG  A OP1    1 
ATOM   64  O  OP2    . DG  A 1 3  ? 18.44391 -10.11268 -13.31389 1.000 33.87395 ? 3   DG  A OP2    1 
ATOM   65  O  "O5'"  . DG  A 1 3  ? 20.07732 -8.37344  -12.80451 1.000 33.70210 ? 3   DG  A "O5'"  1 
ATOM   66  C  "C5'"  . DG  A 1 3  ? 20.91671 -7.34084  -13.19661 1.000 32.87872 ? 3   DG  A "C5'"  1 
ATOM   67  C  "C4'"  . DG  A 1 3  ? 20.95807 -6.26115  -12.13638 1.000 37.25882 ? 3   DG  A "C4'"  1 
ATOM   68  O  "O4'"  . DG  A 1 3  ? 19.64262 -5.66758  -11.97278 1.000 30.90995 ? 3   DG  A "O4'"  1 
ATOM   69  C  "C3'"  . DG  A 1 3  ? 21.36691 -6.74553  -10.75251 1.000 31.50936 ? 3   DG  A "C3'"  1 
ATOM   70  O  "O3'"  . DG  A 1 3  ? 22.17217 -5.78705  -10.16237 1.000 32.53253 ? 3   DG  A "O3'"  1 
ATOM   71  C  "C2'"  . DG  A 1 3  ? 20.04686 -6.92647  -10.01999 1.000 33.04863 ? 3   DG  A "C2'"  1 
ATOM   72  C  "C1'"  . DG  A 1 3  ? 19.19530 -5.83295  -10.62453 1.000 30.43480 ? 3   DG  A "C1'"  1 
ATOM   73  N  N9     . DG  A 1 3  ? 17.77912 -6.12256  -10.66038 1.000 30.46439 ? 3   DG  A N9     1 
ATOM   74  C  C8     . DG  A 1 3  ? 17.18773 -7.25062  -11.14781 1.000 31.11117 ? 3   DG  A C8     1 
ATOM   75  N  N7     . DG  A 1 3  ? 15.89544 -7.21789  -11.10876 1.000 31.38209 ? 3   DG  A N7     1 
ATOM   76  C  C5     . DG  A 1 3  ? 15.60654 -5.98761  -10.53178 1.000 30.80766 ? 3   DG  A C5     1 
ATOM   77  C  C6     . DG  A 1 3  ? 14.35752 -5.38931  -10.22202 1.000 31.09371 ? 3   DG  A C6     1 
ATOM   78  O  O6     . DG  A 1 3  ? 13.23218 -5.84181  -10.38782 1.000 34.01100 ? 3   DG  A O6     1 
ATOM   79  N  N1     . DG  A 1 3  ? 14.51050 -4.14659  -9.64367  1.000 31.00243 ? 3   DG  A N1     1 
ATOM   80  C  C2     . DG  A 1 3  ? 15.71775 -3.53448  -9.41209  1.000 30.32601 ? 3   DG  A C2     1 
ATOM   81  N  N2     . DG  A 1 3  ? 15.66481 -2.32642  -8.84444  1.000 30.55926 ? 3   DG  A N2     1 
ATOM   82  N  N3     . DG  A 1 3  ? 16.89919 -4.07150  -9.70930  1.000 30.08189 ? 3   DG  A N3     1 
ATOM   83  C  C4     . DG  A 1 3  ? 16.76161 -5.30233  -10.25636 1.000 30.28592 ? 3   DG  A C4     1 
ATOM   84  H  "H5'"  . DG  A 1 3  ? 20.59272 -6.96182  -14.02864 1.000 39.51653 ? 3   DG  A "H5'"  1 
ATOM   85  H  "H5''" . DG  A 1 3  ? 21.81129 -7.68917  -13.33547 1.000 39.51653 ? 3   DG  A "H5''" 1 
ATOM   86  H  "H4'"  . DG  A 1 3  ? 21.56857 -5.56459  -12.42445 1.000 44.77264 ? 3   DG  A "H4'"  1 
ATOM   87  H  "H3'"  . DG  A 1 3  ? 21.81600 -7.60371  -10.80489 1.000 37.50093 ? 3   DG  A "H3'"  1 
ATOM   88  H  "H2'"  . DG  A 1 3  ? 19.66716 -7.80346  -10.18614 1.000 39.72042 ? 3   DG  A "H2'"  1 
ATOM   89  H  "H2''" . DG  A 1 3  ? 20.15316 -6.80440  -9.06359  1.000 39.72042 ? 3   DG  A "H2''" 1 
ATOM   90  H  "H1'"  . DG  A 1 3  ? 19.34059 -5.01672  -10.12098 1.000 36.21146 ? 3   DG  A "H1'"  1 
ATOM   91  H  H8     . DG  A 1 3  ? 17.66852 -7.97529  -11.47733 1.000 37.02310 ? 3   DG  A H8     1 
ATOM   92  H  H1     . DG  A 1 3  ? 13.79821 -3.72444  -9.41122  1.000 37.26498 ? 3   DG  A H1     1 
ATOM   93  H  H21    . DG  A 1 3  ? 16.39150 -1.89973  -8.67283  1.000 36.52197 ? 3   DG  A H21    1 
ATOM   94  H  H22    . DG  A 1 3  ? 14.90403 -1.97536  -8.65059  1.000 36.52197 ? 3   DG  A H22    1 
ATOM   95  P  P      . DG  A 1 4  ? 22.86032 -6.06731  -8.74648  1.000 34.47075 ? 4   DG  A P      1 
ATOM   96  O  OP1    . DG  A 1 4  ? 24.14300 -5.29585  -8.80992  1.000 33.59867 ? 4   DG  A OP1    1 
ATOM   97  O  OP2    . DG  A 1 4  ? 22.80728 -7.52281  -8.55307  1.000 41.58077 ? 4   DG  A OP2    1 
ATOM   98  O  "O5'"  . DG  A 1 4  ? 21.83779 -5.49038  -7.67153  1.000 34.81349 ? 4   DG  A "O5'"  1 
ATOM   99  C  "C5'"  . DG  A 1 4  ? 21.46196 -4.14086  -7.72791  1.000 34.36378 ? 4   DG  A "C5'"  1 
ATOM   100 C  "C4'"  . DG  A 1 4  ? 20.45819 -3.80960  -6.65195  1.000 32.45938 ? 4   DG  A "C4'"  1 
ATOM   101 O  "O4'"  . DG  A 1 4  ? 19.11617 -4.18336  -7.08254  1.000 32.14533 ? 4   DG  A "O4'"  1 
ATOM   102 C  "C3'"  . DG  A 1 4  ? 20.67705 -4.54117  -5.32097  1.000 34.04154 ? 4   DG  A "C3'"  1 
ATOM   103 O  "O3'"  . DG  A 1 4  ? 20.52128 -3.65350  -4.23420  1.000 43.29701 ? 4   DG  A "O3'"  1 
ATOM   104 C  "C2'"  . DG  A 1 4  ? 19.60164 -5.61504  -5.33524  1.000 35.38468 ? 4   DG  A "C2'"  1 
ATOM   105 C  "C1'"  . DG  A 1 4  ? 18.48244 -4.89169  -6.03297  1.000 32.41988 ? 4   DG  A "C1'"  1 
ATOM   106 N  N9     . DG  A 1 4  ? 17.49981 -5.77626  -6.58572  1.000 32.05948 ? 4   DG  A N9     1 
ATOM   107 C  C8     . DG  A 1 4  ? 17.74527 -6.94971  -7.23532  1.000 32.10291 ? 4   DG  A C8     1 
ATOM   108 N  N7     . DG  A 1 4  ? 16.67412 -7.56280  -7.61374  1.000 32.25200 ? 4   DG  A N7     1 
ATOM   109 C  C5     . DG  A 1 4  ? 15.64687 -6.74456  -7.17578  1.000 32.22441 ? 4   DG  A C5     1 
ATOM   110 C  C6     . DG  A 1 4  ? 14.26704 -6.89552  -7.31352  1.000 32.67871 ? 4   DG  A C6     1 
ATOM   111 O  O6     . DG  A 1 4  ? 13.66264 -7.81734  -7.85377  1.000 33.27043 ? 4   DG  A O6     1 
ATOM   112 N  N1     . DG  A 1 4  ? 13.57401 -5.84386  -6.74662  1.000 32.85424 ? 4   DG  A N1     1 
ATOM   113 C  C2     . DG  A 1 4  ? 14.14840 -4.78433  -6.11095  1.000 32.73715 ? 4   DG  A C2     1 
ATOM   114 N  N2     . DG  A 1 4  ? 13.30890 -3.88339  -5.59670  1.000 33.39689 ? 4   DG  A N2     1 
ATOM   115 N  N3     . DG  A 1 4  ? 15.44993 -4.62117  -5.97611  1.000 32.42481 ? 4   DG  A N3     1 
ATOM   116 C  C4     . DG  A 1 4  ? 16.13749 -5.63850  -6.54253  1.000 32.10838 ? 4   DG  A C4     1 
ATOM   117 H  "H5'"  . DG  A 1 4  ? 21.07105 -3.95525  -8.59603  1.000 41.29860 ? 4   DG  A "H5'"  1 
ATOM   118 H  "H5''" . DG  A 1 4  ? 22.24897 -3.58605  -7.61082  1.000 41.29860 ? 4   DG  A "H5''" 1 
ATOM   119 H  "H4'"  . DG  A 1 4  ? 20.47434 -2.85186  -6.49904  1.000 38.64095 ? 4   DG  A "H4'"  1 
ATOM   120 H  "H3'"  . DG  A 1 4  ? 21.55792 -4.94700  -5.30475  1.000 40.91190 ? 4   DG  A "H3'"  1 
ATOM   121 H  "H2'"  . DG  A 1 4  ? 19.88509 -6.39933  -5.83067  1.000 42.52368 ? 4   DG  A "H2'"  1 
ATOM   122 H  "H2''" . DG  A 1 4  ? 19.35049 -5.88247  -4.43729  1.000 42.52368 ? 4   DG  A "H2''" 1 
ATOM   123 H  "H1'"  . DG  A 1 4  ? 18.03877 -4.27116  -5.43380  1.000 38.59355 ? 4   DG  A "H1'"  1 
ATOM   124 H  H8     . DG  A 1 4  ? 18.60184 -7.27686  -7.39078  1.000 38.21319 ? 4   DG  A H8     1 
ATOM   125 H  H1     . DG  A 1 4  ? 12.71573 -5.85890  -6.79874  1.000 39.11478 ? 4   DG  A H1     1 
ATOM   126 H  H21    . DG  A 1 4  ? 12.45973 -3.98809  -5.68362  1.000 40.08361 ? 4   DG  A H21    1 
ATOM   127 H  H22    . DG  A 1 4  ? 13.61706 -3.19809  -5.17837  1.000 40.08361 ? 4   DG  A H22    1 
ATOM   128 P  P      . DT  A 1 5  ? 21.04087 -4.05829  -2.77006  1.000 39.19346 ? 5   DT  A P      1 
ATOM   129 O  OP1    . DT  A 1 5  ? 20.81450 -2.83475  -1.96351  1.000 43.39426 ? 5   DT  A OP1    1 
ATOM   130 O  OP2    . DT  A 1 5  ? 22.37285 -4.65889  -2.91120  1.000 42.98699 ? 5   DT  A OP2    1 
ATOM   131 O  "O5'"  . DT  A 1 5  ? 20.15947 -5.36134  -2.35542  1.000 37.43289 ? 5   DT  A "O5'"  1 
ATOM   132 C  "C5'"  . DT  A 1 5  ? 19.01670 -5.28099  -1.50530  1.000 38.11347 ? 5   DT  A "C5'"  1 
ATOM   133 C  "C4'"  . DT  A 1 5  ? 18.01987 -4.21278  -1.95174  1.000 43.02373 ? 5   DT  A "C4'"  1 
ATOM   134 O  "O4'"  . DT  A 1 5  ? 17.24680 -4.66673  -3.09323  1.000 35.67398 ? 5   DT  A "O4'"  1 
ATOM   135 C  "C3'"  . DT  A 1 5  ? 16.96598 -3.89861  -0.93253  1.000 45.72498 ? 5   DT  A "C3'"  1 
ATOM   136 O  "O3'"  . DT  A 1 5  ? 16.41726 -2.64171  -1.19085  1.000 45.99478 ? 5   DT  A "O3'"  1 
ATOM   137 C  "C2'"  . DT  A 1 5  ? 15.96536 -5.02628  -1.14733  1.000 39.35082 ? 5   DT  A "C2'"  1 
ATOM   138 C  "C1'"  . DT  A 1 5  ? 15.95250 -5.10653  -2.65942  1.000 35.89354 ? 5   DT  A "C1'"  1 
ATOM   139 N  N1     . DT  A 1 5  ? 15.74538 -6.43735  -3.21861  1.000 35.51249 ? 5   DT  A N1     1 
ATOM   140 C  C2     . DT  A 1 5  ? 14.48502 -6.86757  -3.48083  1.000 35.61461 ? 5   DT  A C2     1 
ATOM   141 O  O2     . DT  A 1 5  ? 13.49210 -6.22245  -3.21030  1.000 36.02659 ? 5   DT  A O2     1 
ATOM   142 N  N3     . DT  A 1 5  ? 14.41709 -8.10074  -4.06127  1.000 35.65117 ? 5   DT  A N3     1 
ATOM   143 C  C4     . DT  A 1 5  ? 15.46976 -8.91075  -4.41650  1.000 35.57109 ? 5   DT  A C4     1 
ATOM   144 O  O4     . DT  A 1 5  ? 15.30875 -10.01596 -4.92155  1.000 36.04166 ? 5   DT  A O4     1 
ATOM   145 C  C5     . DT  A 1 5  ? 16.77134 -8.38622  -4.11227  1.000 35.39466 ? 5   DT  A C5     1 
ATOM   146 C  C7     . DT  A 1 5  ? 18.00277 -9.16588  -4.44078  1.000 37.16594 ? 5   DT  A C7     1 
ATOM   147 C  C6     . DT  A 1 5  ? 16.84389 -7.18474  -3.54524  1.000 35.38094 ? 5   DT  A C6     1 
ATOM   148 H  "H5'"  . DT  A 1 5  ? 19.31215 -5.07458  -0.60474  1.000 45.42586 ? 5   DT  A "H5'"  1 
ATOM   149 H  "H5''" . DT  A 1 5  ? 18.56996 -6.14198  -1.50154  1.000 45.42586 ? 5   DT  A "H5''" 1 
ATOM   150 H  "H4'"  . DT  A 1 5  ? 18.52328 -3.42215  -2.20150  1.000 51.69054 ? 5   DT  A "H4'"  1 
ATOM   151 H  "H3'"  . DT  A 1 5  ? 17.32257 -3.93191  -0.03107  1.000 54.93203 ? 5   DT  A "H3'"  1 
ATOM   152 H  "H2'"  . DT  A 1 5  ? 16.26735 -5.85608  -0.74591  1.000 47.28305 ? 5   DT  A "H2'"  1 
ATOM   153 H  "H2''" . DT  A 1 5  ? 15.09083 -4.80339  -0.79177  1.000 47.28305 ? 5   DT  A "H2''" 1 
ATOM   154 H  "H1'"  . DT  A 1 5  ? 15.25202 -4.51763  -2.98103  1.000 42.95815 ? 5   DT  A "H1'"  1 
ATOM   155 H  H3     . DT  A 1 5  ? 13.62897 -8.40475  -4.22267  1.000 42.47110 ? 5   DT  A H3     1 
ATOM   156 H  H71    . DT  A 1 5  ? 17.74458 -10.00548 -4.85226  1.000 44.66119 ? 5   DT  A H71    1 
ATOM   157 H  H72    . DT  A 1 5  ? 18.54839 -8.65040  -5.05518  1.000 44.66119 ? 5   DT  A H72    1 
ATOM   158 H  H73    . DT  A 1 5  ? 18.49622 -9.33616  -3.62321  1.000 44.66119 ? 5   DT  A H73    1 
ATOM   159 H  H6     . DT  A 1 5  ? 17.68556 -6.83455  -3.36124  1.000 42.14683 ? 5   DT  A H6     1 
ATOM   160 P  P      . DG  A 1 6  ? 16.08583 -1.69607  0.05642   1.000 54.31283 ? 6   DG  A P      1 
ATOM   161 O  OP1    . DG  A 1 6  ? 15.87582 -0.31256  -0.45394  1.000 56.87719 ? 6   DG  A OP1    1 
ATOM   162 O  OP2    . DG  A 1 6  ? 16.97389 -2.06602  1.21114   1.000 45.43029 ? 6   DG  A OP2    1 
ATOM   163 O  "O5'"  . DG  A 1 6  ? 14.70234 -2.25074  0.57360   1.000 48.90076 ? 6   DG  A "O5'"  1 
ATOM   164 C  "C5'"  . DG  A 1 6  ? 14.59871 -2.57096  1.91454   1.000 33.74446 ? 6   DG  A "C5'"  1 
ATOM   165 C  "C4'"  . DG  A 1 6  ? 13.22793 -3.06319  2.24021   1.000 34.76881 ? 6   DG  A "C4'"  1 
ATOM   166 O  "O4'"  . DG  A 1 6  ? 12.83088 -4.12013  1.30264   1.000 31.16119 ? 6   DG  A "O4'"  1 
ATOM   167 C  "C3'"  . DG  A 1 6  ? 13.14848 -3.65091  3.60918   1.000 32.84188 ? 6   DG  A "C3'"  1 
ATOM   168 O  "O3'"  . DG  A 1 6  ? 11.95849 -3.28949  4.20306   1.000 35.16259 ? 6   DG  A "O3'"  1 
ATOM   169 C  "C2'"  . DG  A 1 6  ? 13.28274 -5.14919  3.34614   1.000 31.06593 ? 6   DG  A "C2'"  1 
ATOM   170 C  "C1'"  . DG  A 1 6  ? 12.61061 -5.32028  1.99396   1.000 28.07910 ? 6   DG  A "C1'"  1 
ATOM   171 N  N9     . DG  A 1 6  ? 13.13344 -6.42052  1.19737   1.000 27.48747 ? 6   DG  A N9     1 
ATOM   172 C  C8     . DG  A 1 6  ? 14.44961 -6.78561  1.06169   1.000 26.14129 ? 6   DG  A C8     1 
ATOM   173 N  N7     . DG  A 1 6  ? 14.62563 -7.81286  0.28492   1.000 25.89693 ? 6   DG  A N7     1 
ATOM   174 C  C5     . DG  A 1 6  ? 13.34247 -8.16117  -0.11722  1.000 25.20078 ? 6   DG  A C5     1 
ATOM   175 C  C6     . DG  A 1 6  ? 12.90275 -9.19883  -0.97419  1.000 24.88651 ? 6   DG  A C6     1 
ATOM   176 O  O6     . DG  A 1 6  ? 13.58625 -10.03129 -1.57783  1.000 22.83301 ? 6   DG  A O6     1 
ATOM   177 N  N1     . DG  A 1 6  ? 11.51600 -9.19761  -1.12461  1.000 22.53303 ? 6   DG  A N1     1 
ATOM   178 C  C2     . DG  A 1 6  ? 10.67451 -8.31423  -0.51889  1.000 23.90761 ? 6   DG  A C2     1 
ATOM   179 N  N2     . DG  A 1 6  ? 9.36848  -8.46218  -0.77934  1.000 27.17234 ? 6   DG  A N2     1 
ATOM   180 N  N3     . DG  A 1 6  ? 11.07326 -7.33723  0.26943   1.000 25.65456 ? 6   DG  A N3     1 
ATOM   181 C  C4     . DG  A 1 6  ? 12.41305 -7.31938  0.43340   1.000 25.86164 ? 6   DG  A C4     1 
ATOM   182 H  "H5'"  . DG  A 1 6  ? 14.78995 -1.78293  2.44683   1.000 40.55541 ? 6   DG  A "H5'"  1 
ATOM   183 H  "H5''" . DG  A 1 6  ? 15.24536 -3.26145  2.12895   1.000 40.55541 ? 6   DG  A "H5''" 1 
ATOM   184 H  "H4'"  . DG  A 1 6  ? 12.57743 -2.35026  2.14293   1.000 41.78463 ? 6   DG  A "H4'"  1 
ATOM   185 H  "H3'"  . DG  A 1 6  ? 13.89076 -3.36429  4.16395   1.000 39.47232 ? 6   DG  A "H3'"  1 
ATOM   186 H  "H2'"  . DG  A 1 6  ? 14.21438 -5.41697  3.31105   1.000 37.34118 ? 6   DG  A "H2'"  1 
ATOM   187 H  "H2''" . DG  A 1 6  ? 12.83081 -5.66725  4.03045   1.000 37.34118 ? 6   DG  A "H2''" 1 
ATOM   188 H  "H1'"  . DG  A 1 6  ? 11.65926 -5.45850  2.12329   1.000 33.75699 ? 6   DG  A "H1'"  1 
ATOM   189 H  H8     . DG  A 1 6  ? 15.14821 -6.34083  1.48480   1.000 31.43161 ? 6   DG  A H8     1 
ATOM   190 H  H1     . DG  A 1 6  ? 11.16824 -9.79600  -1.63510  1.000 27.10169 ? 6   DG  A H1     1 
ATOM   191 H  H21    . DG  A 1 6  ? 8.79689  -7.92123  -0.43259  1.000 32.66887 ? 6   DG  A H21    1 
ATOM   192 H  H22    . DG  A 1 6  ? 9.10185  -9.09811  -1.29326  1.000 32.66887 ? 6   DG  A H22    1 
ATOM   193 P  P      . DG  A 1 7  ? 11.67441 -3.75623  5.68998   1.000 41.17044 ? 7   DG  A P      1 
ATOM   194 O  OP1    . DG  A 1 7  ? 10.85492 -2.68343  6.29539   1.000 51.09360 ? 7   DG  A OP1    1 
ATOM   195 O  OP2    . DG  A 1 7  ? 12.94072 -4.23505  6.30880   1.000 34.62590 ? 7   DG  A OP2    1 
ATOM   196 O  "O5'"  . DG  A 1 7  ? 10.77192 -5.04389  5.47604   1.000 33.03630 ? 7   DG  A "O5'"  1 
ATOM   197 C  "C5'"  . DG  A 1 7  ? 9.70232  -5.00844  4.55447   1.000 32.41392 ? 7   DG  A "C5'"  1 
ATOM   198 C  "C4'"  . DG  A 1 7  ? 9.05971  -6.37040  4.43286   1.000 34.83713 ? 7   DG  A "C4'"  1 
ATOM   199 O  "O4'"  . DG  A 1 7  ? 9.78769  -7.16705  3.45436   1.000 27.10296 ? 7   DG  A "O4'"  1 
ATOM   200 C  "C3'"  . DG  A 1 7  ? 9.06284  -7.20712  5.71438   1.000 31.83116 ? 7   DG  A "C3'"  1 
ATOM   201 O  "O3'"  . DG  A 1 7  ? 7.83714  -7.90591  5.85230   1.000 37.47123 ? 7   DG  A "O3'"  1 
ATOM   202 C  "C2'"  . DG  A 1 7  ? 10.21319 -8.16303  5.48499   1.000 28.71851 ? 7   DG  A "C2'"  1 
ATOM   203 C  "C1'"  . DG  A 1 7  ? 10.04085 -8.43219  4.01919   1.000 26.80238 ? 7   DG  A "C1'"  1 
ATOM   204 N  N9     . DG  A 1 7  ? 11.19223 -9.05648  3.38637   1.000 24.78218 ? 7   DG  A N9     1 
ATOM   205 C  C8     . DG  A 1 7  ? 12.51701 -8.77294  3.58897   1.000 24.66437 ? 7   DG  A C8     1 
ATOM   206 N  N7     . DG  A 1 7  ? 13.32441 -9.53193  2.89041   1.000 25.01915 ? 7   DG  A N7     1 
ATOM   207 C  C5     . DG  A 1 7  ? 12.47527 -10.38588 2.21426   1.000 21.93495 ? 7   DG  A C5     1 
ATOM   208 C  C6     . DG  A 1 7  ? 12.77081 -11.42420 1.31502   1.000 21.91020 ? 7   DG  A C6     1 
ATOM   209 O  O6     . DG  A 1 7  ? 13.87089 -11.80644 0.93533   1.000 24.99970 ? 7   DG  A O6     1 
ATOM   210 N  N1     . DG  A 1 7  ? 11.61916 -12.03636 0.84040   1.000 23.53788 ? 7   DG  A N1     1 
ATOM   211 C  C2     . DG  A 1 7  ? 10.34637 -11.67943 1.19734   1.000 24.79095 ? 7   DG  A C2     1 
ATOM   212 N  N2     . DG  A 1 7  ? 9.34813  -12.38324 0.63505   1.000 22.09712 ? 7   DG  A N2     1 
ATOM   213 N  N3     . DG  A 1 7  ? 10.06076 -10.69897 2.04411   1.000 17.88704 ? 7   DG  A N3     1 
ATOM   214 C  C4     . DG  A 1 7  ? 11.16731 -10.10639 2.50936   1.000 24.70113 ? 7   DG  A C4     1 
ATOM   215 H  "H5'"  . DG  A 1 7  ? 10.03602 -4.73271  3.68642   1.000 38.95877 ? 7   DG  A "H5'"  1 
ATOM   216 H  "H5''" . DG  A 1 7  ? 9.04005  -4.36725  4.85644   1.000 38.95877 ? 7   DG  A "H5''" 1 
ATOM   217 H  "H4'"  . DG  A 1 7  ? 8.14457  -6.25674  4.13201   1.000 41.86661 ? 7   DG  A "H4'"  1 
ATOM   218 H  "H3'"  . DG  A 1 7  ? 9.22787  -6.64127  6.48476   1.000 38.25946 ? 7   DG  A "H3'"  1 
ATOM   219 H  "H2'"  . DG  A 1 7  ? 11.06990 -7.75164  5.67919   1.000 34.52428 ? 7   DG  A "H2'"  1 
ATOM   220 H  "H2''" . DG  A 1 7  ? 10.12356 -8.97089  6.01435   1.000 34.52428 ? 7   DG  A "H2''" 1 
ATOM   221 H  "H1'"  . DG  A 1 7  ? 9.28126  -9.01425  3.86062   1.000 32.22491 ? 7   DG  A "H1'"  1 
ATOM   222 H  H8     . DG  A 1 7  ? 12.81411 -8.10683  4.16597   1.000 29.65931 ? 7   DG  A H8     1 
ATOM   223 H  H1     . DG  A 1 7  ? 11.71141 -12.68502 0.28334   1.000 28.30751 ? 7   DG  A H1     1 
ATOM   224 H  H21    . DG  A 1 7  ? 8.53039  -12.19670 0.82505   1.000 26.57860 ? 7   DG  A H21    1 
ATOM   225 H  H22    . DG  A 1 7  ? 9.52742  -13.01992 0.08541   1.000 26.57860 ? 7   DG  A H22    1 
ATOM   226 P  P      . DT  A 1 8  ? 7.15467  -8.11064  7.29050   1.000 37.27691 ? 8   DT  A P      1 
ATOM   227 O  OP1    . DT  A 1 8  ? 5.70171  -8.09401  7.05212   1.000 52.71471 ? 8   DT  A OP1    1 
ATOM   228 O  OP2    . DT  A 1 8  ? 7.77918  -7.18799  8.27279   1.000 36.60205 ? 8   DT  A OP2    1 
ATOM   229 O  "O5'"  . DT  A 1 8  ? 7.49653  -9.61343  7.63116   1.000 36.29230 ? 8   DT  A "O5'"  1 
ATOM   230 C  "C5'"  . DT  A 1 8  ? 8.29804  -9.91499  8.73679   1.000 35.24606 ? 8   DT  A "C5'"  1 
ATOM   231 C  "C4'"  . DT  A 1 8  ? 9.12792  -11.13314 8.43941   1.000 25.13384 ? 8   DT  A "C4'"  1 
ATOM   232 O  "O4'"  . DT  A 1 8  ? 10.48947 -10.75881 8.52360   1.000 27.03978 ? 8   DT  A "O4'"  1 
ATOM   233 C  "C3'"  . DT  A 1 8  ? 8.95755  -12.33400 9.39090   1.000 24.06399 ? 8   DT  A "C3'"  1 
ATOM   234 O  "O3'"  . DT  A 1 8  ? 8.52566  -13.46443 8.66466   1.000 21.44807 ? 8   DT  A "O3'"  1 
ATOM   235 C  "C2'"  . DT  A 1 8  ? 10.36331 -12.54694 9.96547   1.000 24.53516 ? 8   DT  A "C2'"  1 
ATOM   236 C  "C1'"  . DT  A 1 8  ? 11.23112 -11.85383 8.94127   1.000 25.20569 ? 8   DT  A "C1'"  1 
ATOM   237 N  N1     . DT  A 1 8  ? 12.49608 -11.34239 9.43321   1.000 25.37748 ? 8   DT  A N1     1 
ATOM   238 C  C2     . DT  A 1 8  ? 13.65505 -11.99518 9.11612   1.000 22.66561 ? 8   DT  A C2     1 
ATOM   239 O  O2     . DT  A 1 8  ? 13.68414 -13.01268 8.46589   1.000 22.63353 ? 8   DT  A O2     1 
ATOM   240 N  N3     . DT  A 1 8  ? 14.78435 -11.41163 9.59318   1.000 24.01511 ? 8   DT  A N3     1 
ATOM   241 C  C4     . DT  A 1 8  ? 14.87378 -10.26072 10.34694  1.000 23.87895 ? 8   DT  A C4     1 
ATOM   242 O  O4     . DT  A 1 8  ? 15.93841 -9.81528  10.72724  1.000 23.26070 ? 8   DT  A O4     1 
ATOM   243 C  C5     . DT  A 1 8  ? 13.61923 -9.61880  10.64039  1.000 25.69190 ? 8   DT  A C5     1 
ATOM   244 C  C7     . DT  A 1 8  ? 13.57519 -8.37170  11.46430  1.000 32.20753 ? 8   DT  A C7     1 
ATOM   245 C  C6     . DT  A 1 8  ? 12.50437 -10.17768 10.15897  1.000 27.68172 ? 8   DT  A C6     1 
ATOM   246 H  "H5'"  . DT  A 1 8  ? 7.73595  -10.08533 9.50876   1.000 42.35733 ? 8   DT  A "H5'"  1 
ATOM   247 H  "H5''" . DT  A 1 8  ? 8.88086  -9.16407  8.93005   1.000 42.35733 ? 8   DT  A "H5''" 1 
ATOM   248 H  "H4'"  . DT  A 1 8  ? 8.91903  -11.44968 7.54663   1.000 30.22267 ? 8   DT  A "H4'"  1 
ATOM   249 H  "H3'"  . DT  A 1 8  ? 8.33669  -12.10850 10.10123  1.000 28.93885 ? 8   DT  A "H3'"  1 
ATOM   250 H  "H2'"  . DT  A 1 8  ? 10.45380 -12.13895 10.84083  1.000 29.50425 ? 8   DT  A "H2'"  1 
ATOM   251 H  "H2''" . DT  A 1 8  ? 10.57938 -13.49017 10.03281  1.000 29.50425 ? 8   DT  A "H2''" 1 
ATOM   252 H  "H1'"  . DT  A 1 8  ? 11.40837 -12.47541 8.21800   1.000 30.30889 ? 8   DT  A "H1'"  1 
ATOM   253 H  H3     . DT  A 1 8  ? 15.52623 -11.80343 9.40419   1.000 28.88019 ? 8   DT  A H3     1 
ATOM   254 H  H71    . DT  A 1 8  ? 13.18612 -7.65752  10.93565  1.000 38.71110 ? 8   DT  A H71    1 
ATOM   255 H  H72    . DT  A 1 8  ? 13.03317 -8.53286  12.25243  1.000 38.71110 ? 8   DT  A H72    1 
ATOM   256 H  H73    . DT  A 1 8  ? 14.47838 -8.13459  11.72684  1.000 38.71110 ? 8   DT  A H73    1 
ATOM   257 H  H6     . DT  A 1 8  ? 11.69246 -9.75540  10.32442  1.000 33.28012 ? 8   DT  A H6     1 
ATOM   258 P  P      . DC  A 1 9  ? 7.60166  -14.59245 9.32327   1.000 32.85099 ? 9   DC  A P      1 
ATOM   259 O  OP1    . DC  A 1 9  ? 6.24751  -14.02294 9.33467   1.000 31.75753 ? 9   DC  A OP1    1 
ATOM   260 O  OP2    . DC  A 1 9  ? 8.17454  -15.14145 10.57649  1.000 36.23406 ? 9   DC  A OP2    1 
ATOM   261 O  "O5'"  . DC  A 1 9  ? 7.66203  -15.72591 8.23633   1.000 30.64786 ? 9   DC  A "O5'"  1 
ATOM   262 C  "C5'"  . DC  A 1 9  ? 6.77657  -15.67852 7.19008   1.000 28.21371 ? 9   DC  A "C5'"  1 
ATOM   263 C  "C4'"  . DC  A 1 9  ? 7.10325  -16.75083 6.18690   1.000 28.02336 ? 9   DC  A "C4'"  1 
ATOM   264 O  "O4'"  . DC  A 1 9  ? 8.34148  -16.40935 5.54479   1.000 24.26041 ? 9   DC  A "O4'"  1 
ATOM   265 C  "C3'"  . DC  A 1 9  ? 7.30455  -18.14967 6.75533   1.000 25.74512 ? 9   DC  A "C3'"  1 
ATOM   266 O  "O3'"  . DC  A 1 9  ? 6.77106  -19.08957 5.87496   1.000 22.44784 ? 9   DC  A "O3'"  1 
ATOM   267 C  "C2'"  . DC  A 1 9  ? 8.80590  -18.27443 6.86273   1.000 24.30070 ? 9   DC  A "C2'"  1 
ATOM   268 C  "C1'"  . DC  A 1 9  ? 9.27597  -17.43454 5.68566   1.000 22.19955 ? 9   DC  A "C1'"  1 
ATOM   269 N  N1     . DC  A 1 9  ? 10.59232 -16.79658 5.87413   1.000 21.18726 ? 9   DC  A N1     1 
ATOM   270 C  C2     . DC  A 1 9  ? 11.68488 -17.21964 5.11921   1.000 21.76706 ? 9   DC  A C2     1 
ATOM   271 O  O2     . DC  A 1 9  ? 11.51123 -18.11620 4.30824   1.000 26.14022 ? 9   DC  A O2     1 
ATOM   272 N  N3     . DC  A 1 9  ? 12.90253 -16.62031 5.30798   1.000 22.18197 ? 9   DC  A N3     1 
ATOM   273 C  C4     . DC  A 1 9  ? 13.01465 -15.64303 6.20705   1.000 23.28081 ? 9   DC  A C4     1 
ATOM   274 N  N4     . DC  A 1 9  ? 14.19688 -15.07657 6.36945   1.000 18.89574 ? 9   DC  A N4     1 
ATOM   275 C  C5     . DC  A 1 9  ? 11.90444 -15.19552 6.97570   1.000 24.28582 ? 9   DC  A C5     1 
ATOM   276 C  C6     . DC  A 1 9  ? 10.72124 -15.78688 6.77249   1.000 24.71419 ? 9   DC  A C6     1 
ATOM   277 H  "H5'"  . DC  A 1 9  ? 6.82901  -14.80960 6.76215   1.000 33.91852 ? 9   DC  A "H5'"  1 
ATOM   278 H  "H5''" . DC  A 1 9  ? 5.87561  -15.81243 7.52361   1.000 33.91852 ? 9   DC  A "H5''" 1 
ATOM   279 H  "H4'"  . DC  A 1 9  ? 6.39340  -16.79702 5.52745   1.000 33.69010 ? 9   DC  A "H4'"  1 
ATOM   280 H  "H3'"  . DC  A 1 9  ? 6.90394  -18.22116 7.63584   1.000 30.95621 ? 9   DC  A "H3'"  1 
ATOM   281 H  "H2'"  . DC  A 1 9  ? 9.13207  -17.91953 7.70449   1.000 29.22291 ? 9   DC  A "H2'"  1 
ATOM   282 H  "H2''" . DC  A 1 9  ? 9.09225  -19.19721 6.77691   1.000 29.22291 ? 9   DC  A "H2''" 1 
ATOM   283 H  "H1'"  . DC  A 1 9  ? 9.29802  -17.99655 4.89537   1.000 26.70152 ? 9   DC  A "H1'"  1 
ATOM   284 H  H41    . DC  A 1 9  ? 14.29526 -14.44371 6.94339   1.000 22.73695 ? 9   DC  A H41    1 
ATOM   285 H  H42    . DC  A 1 9  ? 14.86819 -15.34064 5.90124   1.000 22.73695 ? 9   DC  A H42    1 
ATOM   286 H  H5     . DC  A 1 9  ? 11.99801 -14.51288 7.60032   1.000 29.20504 ? 9   DC  A H5     1 
ATOM   287 H  H6     . DC  A 1 9  ? 9.97753  -15.50243 7.25299   1.000 29.71909 ? 9   DC  A H6     1 
ATOM   288 P  P      . DT  A 1 10 ? 6.63590  -20.61707 6.30106   1.000 28.93522 ? 10  DT  A P      1 
ATOM   289 O  OP1    . DT  A 1 10 ? 5.60585  -21.23801 5.43231   1.000 25.46591 ? 10  DT  A OP1    1 
ATOM   290 O  OP2    . DT  A 1 10 ? 6.40708  -20.70597 7.76980   1.000 29.97732 ? 10  DT  A OP2    1 
ATOM   291 O  "O5'"  . DT  A 1 10 ? 8.06958  -21.21833 5.96223   1.000 24.63946 ? 10  DT  A "O5'"  1 
ATOM   292 C  "C5'"  . DT  A 1 10 ? 8.22503  -22.62514 5.95728   1.000 31.74085 ? 10  DT  A "C5'"  1 
ATOM   293 C  "C4'"  . DT  A 1 10 ? 9.43278  -23.01533 5.16065   1.000 31.54900 ? 10  DT  A "C4'"  1 
ATOM   294 O  "O4'"  . DT  A 1 10 ? 9.23080  -22.63634 3.78409   1.000 28.18364 ? 10  DT  A "O4'"  1 
ATOM   295 C  "C3'"  . DT  A 1 10 ? 10.71704 -22.33498 5.60518   1.000 28.97983 ? 10  DT  A "C3'"  1 
ATOM   296 O  "O3'"  . DT  A 1 10 ? 11.75777 -23.22154 5.58827   1.000 29.64650 ? 10  DT  A "O3'"  1 
ATOM   297 C  "C2'"  . DT  A 1 10 ? 10.91911 -21.23959 4.60636   1.000 28.58286 ? 10  DT  A "C2'"  1 
ATOM   298 C  "C1'"  . DT  A 1 10 ? 10.27732 -21.80161 3.36178   1.000 30.02646 ? 10  DT  A "C1'"  1 
ATOM   299 N  N1     . DT  A 1 10 ? 9.70813  -20.77532 2.51565   1.000 27.45174 ? 10  DT  A N1     1 
ATOM   300 C  C2     . DT  A 1 10 ? 10.34888 -20.42387 1.34352   1.000 30.16256 ? 10  DT  A C2     1 
ATOM   301 O  O2     . DT  A 1 10 ? 11.39802 -20.93050 0.97148   1.000 31.05125 ? 10  DT  A O2     1 
ATOM   302 N  N3     . DT  A 1 10 ? 9.71323  -19.44235 0.62330   1.000 29.33462 ? 10  DT  A N3     1 
ATOM   303 C  C4     . DT  A 1 10 ? 8.53458  -18.80459 0.95032   1.000 24.94645 ? 10  DT  A C4     1 
ATOM   304 O  O4     . DT  A 1 10 ? 8.04512  -17.93444 0.24125   1.000 25.54067 ? 10  DT  A O4     1 
ATOM   305 C  C5     . DT  A 1 10 ? 7.91528  -19.23846 2.18806   1.000 22.56586 ? 10  DT  A C5     1 
ATOM   306 C  C7     . DT  A 1 10 ? 6.64832  -18.61617 2.64977   1.000 25.54274 ? 10  DT  A C7     1 
ATOM   307 C  C6     . DT  A 1 10 ? 8.52532  -20.18890 2.89659   1.000 25.62897 ? 10  DT  A C6     1 
ATOM   308 H  "H5'"  . DT  A 1 10 ? 7.43680  -23.03415 5.56701   1.000 38.15108 ? 10  DT  A "H5'"  1 
ATOM   309 H  "H5''" . DT  A 1 10 ? 8.32586  -22.94049 6.86903   1.000 38.15108 ? 10  DT  A "H5''" 1 
ATOM   310 H  "H4'"  . DT  A 1 10 ? 9.55831  -23.97645 5.19806   1.000 37.92087 ? 10  DT  A "H4'"  1 
ATOM   311 H  "H3'"  . DT  A 1 10 ? 10.58980 -21.95723 6.48949   1.000 34.83785 ? 10  DT  A "H3'"  1 
ATOM   312 H  "H2'"  . DT  A 1 10 ? 10.48166 -20.42116 4.88869   1.000 34.36149 ? 10  DT  A "H2'"  1 
ATOM   313 H  "H2''" . DT  A 1 10 ? 11.86219 -21.06135 4.46589   1.000 34.36149 ? 10  DT  A "H2''" 1 
ATOM   314 H  "H1'"  . DT  A 1 10 ? 10.92849 -22.32635 2.87033   1.000 36.09381 ? 10  DT  A "H1'"  1 
ATOM   315 H  H3     . DT  A 1 10 ? 10.09048 -19.19925 -0.11031  1.000 35.26361 ? 10  DT  A H3     1 
ATOM   316 H  H71    . DT  A 1 10 ? 5.97493  -19.30723 2.74913   1.000 30.71335 ? 10  DT  A H71    1 
ATOM   317 H  H72    . DT  A 1 10 ? 6.80302  -18.18005 3.50227   1.000 30.71335 ? 10  DT  A H72    1 
ATOM   318 H  H73    . DT  A 1 10 ? 6.35879  -17.96426 1.99243   1.000 30.71335 ? 10  DT  A H73    1 
ATOM   319 H  H6     . DT  A 1 10 ? 8.12966  -20.46962 3.69003   1.000 30.81683 ? 10  DT  A H6     1 
ATOM   320 P  P      . DA  A 1 11 ? 12.75493 -23.25391 6.82964   1.000 31.66029 ? 11  DA  A P      1 
ATOM   321 O  OP1    . DA  A 1 11 ? 13.60434 -24.45382 6.69267   1.000 31.13582 ? 11  DA  A OP1    1 
ATOM   322 O  OP2    . DA  A 1 11 ? 11.90593 -23.06622 8.03922   1.000 34.36380 ? 11  DA  A OP2    1 
ATOM   323 O  "O5'"  . DA  A 1 11 ? 13.65111 -21.98195 6.61280   1.000 27.89285 ? 11  DA  A "O5'"  1 
ATOM   324 C  "C5'"  . DA  A 1 11 ? 14.56700 -21.95399 5.57425   1.000 27.71062 ? 11  DA  A "C5'"  1 
ATOM   325 C  "C4'"  . DA  A 1 11 ? 15.60582 -20.91439 5.84615   1.000 23.32565 ? 11  DA  A "C4'"  1 
ATOM   326 O  "O4'"  . DA  A 1 11 ? 14.96487 -19.64266 5.88969   1.000 22.66949 ? 11  DA  A "O4'"  1 
ATOM   327 C  "C3'"  . DA  A 1 11 ? 16.29953 -21.06773 7.17154   1.000 19.83713 ? 11  DA  A "C3'"  1 
ATOM   328 O  "O3'"  . DA  A 1 11 ? 17.41838 -21.87511 7.03911   1.000 28.43171 ? 11  DA  A "O3'"  1 
ATOM   329 C  "C2'"  . DA  A 1 11 ? 16.65789 -19.65518 7.52943   1.000 25.77644 ? 11  DA  A "C2'"  1 
ATOM   330 C  "C1'"  . DA  A 1 11 ? 15.54917 -18.84811 6.88665   1.000 22.80655 ? 11  DA  A "C1'"  1 
ATOM   331 N  N9     . DA  A 1 11 ? 14.48736 -18.41250 7.78229   1.000 23.64995 ? 11  DA  A N9     1 
ATOM   332 C  C8     . DA  A 1 11 ? 13.18097 -18.81998 7.78204   1.000 23.25299 ? 11  DA  A C8     1 
ATOM   333 N  N7     . DA  A 1 11 ? 12.43160 -18.18697 8.65823   1.000 22.25139 ? 11  DA  A N7     1 
ATOM   334 C  C5     . DA  A 1 11 ? 13.31634 -17.30950 9.25592   1.000 21.73996 ? 11  DA  A C5     1 
ATOM   335 C  C6     . DA  A 1 11 ? 13.16366 -16.35816 10.27656  1.000 24.99562 ? 11  DA  A C6     1 
ATOM   336 N  N6     . DA  A 1 11 ? 12.00629 -16.12418 10.89692  1.000 27.54944 ? 11  DA  A N6     1 
ATOM   337 N  N1     . DA  A 1 11 ? 14.24243 -15.64947 10.64139  1.000 24.17588 ? 11  DA  A N1     1 
ATOM   338 C  C2     . DA  A 1 11 ? 15.40454 -15.89030 10.03594  1.000 24.51524 ? 11  DA  A C2     1 
ATOM   339 N  N3     . DA  A 1 11 ? 15.67412 -16.76134 9.07350   1.000 23.26433 ? 11  DA  A N3     1 
ATOM   340 C  C4     . DA  A 1 11 ? 14.57475 -17.44034 8.72126   1.000 22.12311 ? 11  DA  A C4     1 
ATOM   341 H  "H5'"  . DA  A 1 11 ? 14.10988 -21.74632 4.74430   1.000 33.31480 ? 11  DA  A "H5'"  1 
ATOM   342 H  "H5''" . DA  A 1 11 ? 14.99108 -22.82253 5.49243   1.000 33.31480 ? 11  DA  A "H5''" 1 
ATOM   343 H  "H4'"  . DA  A 1 11 ? 16.27235 -20.91383 5.14142   1.000 28.05284 ? 11  DA  A "H4'"  1 
ATOM   344 H  "H3'"  . DA  A 1 11 ? 15.69250 -21.43599 7.83245   1.000 23.79869 ? 11  DA  A "H3'"  1 
ATOM   345 H  "H2'"  . DA  A 1 11 ? 16.67046 -19.52968 8.49120   1.000 30.99378 ? 11  DA  A "H2'"  1 
ATOM   346 H  "H2''" . DA  A 1 11 ? 17.52416 -19.41095 7.16774   1.000 30.99378 ? 11  DA  A "H2''" 1 
ATOM   347 H  "H1'"  . DA  A 1 11 ? 15.96417 -18.06872 6.48512   1.000 27.42992 ? 11  DA  A "H1'"  1 
ATOM   348 H  H8     . DA  A 1 11 ? 12.85407 -19.48162 7.21611   1.000 27.96565 ? 11  DA  A H8     1 
ATOM   349 H  H61    . DA  A 1 11 ? 11.96309 -15.52932 11.51650  1.000 33.12139 ? 11  DA  A H61    1 
ATOM   350 H  H62    . DA  A 1 11 ? 11.30327 -16.56818 10.67733  1.000 33.12139 ? 11  DA  A H62    1 
ATOM   351 H  H2     . DA  A 1 11 ? 16.12384 -15.37819 10.32791  1.000 29.48034 ? 11  DA  A H2     1 
ATOM   352 P  P      . DT  A 1 12 ? 17.93339 -22.78569 8.24665   1.000 33.02219 ? 12  DT  A P      1 
ATOM   353 O  OP1    . DT  A 1 12 ? 18.98961 -23.63016 7.64626   1.000 40.51287 ? 12  DT  A OP1    1 
ATOM   354 O  OP2    . DT  A 1 12 ? 16.82895 -23.43438 8.98468   1.000 30.44879 ? 12  DT  A OP2    1 
ATOM   355 O  "O5'"  . DT  A 1 12 ? 18.63669 -21.75657 9.24144   1.000 31.87536 ? 12  DT  A "O5'"  1 
ATOM   356 C  "C5'"  . DT  A 1 12 ? 19.72418 -21.00418 8.83640   1.000 29.28795 ? 12  DT  A "C5'"  1 
ATOM   357 C  "C4'"  . DT  A 1 12 ? 20.06078 -20.01354 9.89808   1.000 22.07187 ? 12  DT  A "C4'"  1 
ATOM   358 O  "O4'"  . DT  A 1 12 ? 18.88066 -19.22907 10.16955  1.000 24.43097 ? 12  DT  A "O4'"  1 
ATOM   359 C  "C3'"  . DT  A 1 12 ? 20.47017 -20.61302 11.23076  1.000 30.94604 ? 12  DT  A "C3'"  1 
ATOM   360 O  "O3'"  . DT  A 1 12 ? 21.46253 -19.81969 11.81677  1.000 28.34335 ? 12  DT  A "O3'"  1 
ATOM   361 C  "C2'"  . DT  A 1 12 ? 19.17743 -20.59111 12.02137  1.000 31.40442 ? 12  DT  A "C2'"  1 
ATOM   362 C  "C1'"  . DT  A 1 12 ? 18.54809 -19.30438 11.54175  1.000 29.43451 ? 12  DT  A "C1'"  1 
ATOM   363 N  N1     . DT  A 1 12 ? 17.05800 -19.24049 11.69002  1.000 24.31498 ? 12  DT  A N1     1 
ATOM   364 C  C2     . DT  A 1 12 ? 16.47797 -18.18958 12.37503  1.000 27.62437 ? 12  DT  A C2     1 
ATOM   365 O  O2     . DT  A 1 12 ? 17.11179 -17.28695 12.89197  1.000 28.34625 ? 12  DT  A O2     1 
ATOM   366 N  N3     . DT  A 1 12 ? 15.12643 -18.22351 12.42396  1.000 27.06812 ? 12  DT  A N3     1 
ATOM   367 C  C4     . DT  A 1 12 ? 14.30542 -19.18100 11.88104  1.000 26.90945 ? 12  DT  A C4     1 
ATOM   368 O  O4     . DT  A 1 12 ? 13.08092 -19.13377 12.00090  1.000 25.41511 ? 12  DT  A O4     1 
ATOM   369 C  C5     . DT  A 1 12 ? 14.98549 -20.23746 11.16496  1.000 27.34655 ? 12  DT  A C5     1 
ATOM   370 C  C7     . DT  A 1 12 ? 14.22734 -21.34155 10.52065  1.000 23.39798 ? 12  DT  A C7     1 
ATOM   371 C  C6     . DT  A 1 12 ? 16.30481 -20.20833 11.11118  1.000 27.41052 ? 12  DT  A C6     1 
ATOM   372 H  "H5'"  . DT  A 1 12 ? 19.50995 -20.53893 8.01266   1.000 35.20760 ? 12  DT  A "H5'"  1 
ATOM   373 H  "H5''" . DT  A 1 12 ? 20.48409 -21.58682 8.68157   1.000 35.20760 ? 12  DT  A "H5''" 1 
ATOM   374 H  "H4'"  . DT  A 1 12 ? 20.77686 -19.43519 9.59207   1.000 26.17594 ? 12  DT  A "H4'"  1 
ATOM   375 H  "H3'"  . DT  A 1 12 ? 20.77756 -21.52674 11.12337  1.000 37.19731 ? 12  DT  A "H3'"  1 
ATOM   376 H  "H2'"  . DT  A 1 12 ? 18.62083 -21.35813 11.81452  1.000 37.74736 ? 12  DT  A "H2'"  1 
ATOM   377 H  "H2''" . DT  A 1 12 ? 19.34487 -20.57084 12.97659  1.000 37.74736 ? 12  DT  A "H2''" 1 
ATOM   378 H  "H1'"  . DT  A 1 12 ? 18.92481 -18.55246 12.02506  1.000 35.38347 ? 12  DT  A "H1'"  1 
ATOM   379 H  H3     . DT  A 1 12 ? 14.74049 -17.57677 12.83915  1.000 32.54381 ? 12  DT  A H3     1 
ATOM   380 H  H71    . DT  A 1 12 ? 13.31471 -21.33167 10.84915  1.000 28.13964 ? 12  DT  A H71    1 
ATOM   381 H  H72    . DT  A 1 12 ? 14.23439 -21.21064 9.55955   1.000 28.13964 ? 12  DT  A H72    1 
ATOM   382 H  H73    . DT  A 1 12 ? 14.64964 -22.18614 10.74255  1.000 28.13964 ? 12  DT  A H73    1 
ATOM   383 H  H6     . DT  A 1 12 ? 16.74114 -20.88873 10.65122  1.000 32.95468 ? 12  DT  A H6     1 
ATOM   384 P  P      . DT  A 1 13 ? 22.24036 -20.29560 13.11336  1.000 35.10937 ? 13  DT  A P      1 
ATOM   385 O  OP1    . DT  A 1 13 ? 23.44753 -19.42684 13.08253  1.000 33.46494 ? 13  DT  A OP1    1 
ATOM   386 O  OP2    . DT  A 1 13 ? 22.36581 -21.77831 13.16134  1.000 40.37448 ? 13  DT  A OP2    1 
ATOM   387 O  "O5'"  . DT  A 1 13 ? 21.26711 -19.88858 14.31773  1.000 35.54884 ? 13  DT  A "O5'"  1 
ATOM   388 C  "C5'"  . DT  A 1 13 ? 21.72180 -19.95270 15.68529  1.000 34.71759 ? 13  DT  A "C5'"  1 
ATOM   389 C  "C4'"  . DT  A 1 13 ? 20.96071 -18.96095 16.54699  1.000 30.95029 ? 13  DT  A "C4'"  1 
ATOM   390 O  "O4'"  . DT  A 1 13 ? 20.96435 -17.61794 15.92283  1.000 31.72761 ? 13  DT  A "O4'"  1 
ATOM   391 C  "C3'"  . DT  A 1 13 ? 19.49075 -19.30268 16.74655  1.000 33.87644 ? 13  DT  A "C3'"  1 
ATOM   392 O  "O3'"  . DT  A 1 13 ? 19.09724 -18.93806 18.04491  1.000 37.86293 ? 13  DT  A "O3'"  1 
ATOM   393 C  "C2'"  . DT  A 1 13 ? 18.79170 -18.46651 15.66801  1.000 32.09446 ? 13  DT  A "C2'"  1 
ATOM   394 C  "C1'"  . DT  A 1 13 ? 19.60683 -17.18699 15.72398  1.000 30.18826 ? 13  DT  A "C1'"  1 
ATOM   395 N  N1     . DT  A 1 13 ? 19.52937 -16.35297 14.50869  1.000 26.12387 ? 13  DT  A N1     1 
ATOM   396 C  C2     . DT  A 1 13 ? 18.67491 -15.26626 14.46055  1.000 27.98806 ? 13  DT  A C2     1 
ATOM   397 O  O2     . DT  A 1 13 ? 17.95372 -14.93012 15.37626  1.000 30.23993 ? 13  DT  A O2     1 
ATOM   398 N  N3     . DT  A 1 13 ? 18.69874 -14.57814 13.28437  1.000 27.76415 ? 13  DT  A N3     1 
ATOM   399 C  C4     . DT  A 1 13 ? 19.46362 -14.86250 12.17274  1.000 27.75878 ? 13  DT  A C4     1 
ATOM   400 O  O4     . DT  A 1 13 ? 19.42145 -14.18117 11.15002  1.000 28.76102 ? 13  DT  A O4     1 
ATOM   401 C  C5     . DT  A 1 13 ? 20.32470 -16.00680 12.29625  1.000 27.98151 ? 13  DT  A C5     1 
ATOM   402 C  C7     . DT  A 1 13 ? 21.20013 -16.41197 11.16284  1.000 28.16266 ? 13  DT  A C7     1 
ATOM   403 C  C6     . DT  A 1 13 ? 20.32320 -16.68079 13.44838  1.000 28.13932 ? 13  DT  A C6     1 
ATOM   404 H  "H5'"  . DT  A 1 13 ? 22.66894 -19.74600 15.71855  1.000 41.72317 ? 13  DT  A "H5'"  1 
ATOM   405 H  "H5''" . DT  A 1 13 ? 21.58198 -20.84922 16.02822  1.000 41.72317 ? 13  DT  A "H5''" 1 
ATOM   406 H  "H4'"  . DT  A 1 13 ? 21.40514 -18.89471 17.40664  1.000 37.04720 ? 13  DT  A "H4'"  1 
ATOM   407 H  "H3'"  . DT  A 1 13 ? 19.32629 -20.24531 16.58754  1.000 40.71379 ? 13  DT  A "H3'"  1 
ATOM   408 H  "H2'"  . DT  A 1 13 ? 18.84552 -18.88828 14.79616  1.000 38.57541 ? 13  DT  A "H2'"  1 
ATOM   409 H  "H2''" . DT  A 1 13 ? 17.85970 -18.30788 15.88508  1.000 38.57541 ? 13  DT  A "H2''" 1 
ATOM   410 H  "H1'"  . DT  A 1 13 ? 19.31634 -16.64268 16.47247  1.000 36.28798 ? 13  DT  A "H1'"  1 
ATOM   411 H  H3     . DT  A 1 13 ? 18.18142 -13.89332 13.22959  1.000 33.37904 ? 13  DT  A H3     1 
ATOM   412 H  H71    . DT  A 1 13 ? 22.12677 -16.35737 11.44435  1.000 33.85725 ? 13  DT  A H71    1 
ATOM   413 H  H72    . DT  A 1 13 ? 20.98507 -17.32274 10.90762  1.000 33.85725 ? 13  DT  A H72    1 
ATOM   414 H  H73    . DT  A 1 13 ? 21.04580 -15.81370 10.41507  1.000 33.85725 ? 13  DT  A H73    1 
ATOM   415 H  H6     . DT  A 1 13 ? 20.89245 -17.41136 13.53278  1.000 33.82924 ? 13  DT  A H6     1 
ATOM   416 P  P      . DC  A 1 14 ? 17.92090 -19.72567 18.78247  1.000 38.40518 ? 14  DC  A P      1 
ATOM   417 O  OP1    . DC  A 1 14 ? 17.96313 -19.25715 20.19960  1.000 38.33288 ? 14  DC  A OP1    1 
ATOM   418 O  OP2    . DC  A 1 14 ? 18.02465 -21.17041 18.45834  1.000 45.07255 ? 14  DC  A OP2    1 
ATOM   419 O  "O5'"  . DC  A 1 14 ? 16.58498 -19.21630 18.11215  1.000 41.43100 ? 14  DC  A "O5'"  1 
ATOM   420 C  "C5'"  . DC  A 1 14 ? 16.26505 -17.84910 18.11244  1.000 42.67987 ? 14  DC  A "C5'"  1 
ATOM   421 C  "C4'"  . DC  A 1 14 ? 14.92539 -17.65693 17.46565  1.000 38.77911 ? 14  DC  A "C4'"  1 
ATOM   422 O  "O4'"  . DC  A 1 14 ? 14.94370 -18.27551 16.16183  1.000 31.28031 ? 14  DC  A "O4'"  1 
ATOM   423 C  "C3'"  . DC  A 1 14 ? 13.79604 -18.30906 18.22368  1.000 38.21039 ? 14  DC  A "C3'"  1 
ATOM   424 O  "O3'"  . DC  A 1 14 ? 12.72644 -17.44151 18.30244  1.000 36.16901 ? 14  DC  A "O3'"  1 
ATOM   425 C  "C2'"  . DC  A 1 14 ? 13.48984 -19.58746 17.44488  1.000 38.52298 ? 14  DC  A "C2'"  1 
ATOM   426 C  "C1'"  . DC  A 1 14 ? 13.92399 -19.23687 16.04032  1.000 34.50997 ? 14  DC  A "C1'"  1 
ATOM   427 N  N1     . DC  A 1 14 ? 14.46663 -20.38254 15.25125  1.000 38.27314 ? 14  DC  A N1     1 
ATOM   428 C  C2     . DC  A 1 14 ? 13.59385 -21.18561 14.49649  1.000 38.23343 ? 14  DC  A C2     1 
ATOM   429 O  O2     . DC  A 1 14 ? 12.38133 -20.94706 14.51847  1.000 41.11622 ? 14  DC  A O2     1 
ATOM   430 N  N3     . DC  A 1 14 ? 14.10588 -22.21010 13.75672  1.000 44.74839 ? 14  DC  A N3     1 
ATOM   431 C  C4     . DC  A 1 14 ? 15.42818 -22.43764 13.74315  1.000 42.86576 ? 14  DC  A C4     1 
ATOM   432 N  N4     . DC  A 1 14 ? 15.88475 -23.46355 12.98481  1.000 46.54984 ? 14  DC  A N4     1 
ATOM   433 C  C5     . DC  A 1 14 ? 16.33562 -21.62365 14.50441  1.000 42.16199 ? 14  DC  A C5     1 
ATOM   434 C  C6     . DC  A 1 14 ? 15.81408 -20.61407 15.23123  1.000 40.14561 ? 14  DC  A C6     1 
ATOM   435 H  "H5'"  . DC  A 1 14 ? 16.93933 -17.35592 17.61948  1.000 51.27791 ? 14  DC  A "H5'"  1 
ATOM   436 H  "H5''" . DC  A 1 14 ? 16.23731 -17.52049 19.02466  1.000 51.27791 ? 14  DC  A "H5''" 1 
ATOM   437 H  "H4'"  . DC  A 1 14 ? 14.73426 -16.71268 17.35267  1.000 46.59699 ? 14  DC  A "H4'"  1 
ATOM   438 H  "H3'"  . DC  A 1 14 ? 14.09283 -18.56633 19.11060  1.000 45.91453 ? 14  DC  A "H3'"  1 
ATOM   439 H  "H2'"  . DC  A 1 14 ? 13.99515 -20.33946 17.79138  1.000 46.28964 ? 14  DC  A "H2'"  1 
ATOM   440 H  "H2''" . DC  A 1 14 ? 12.54411 -19.80062 17.47737  1.000 46.28964 ? 14  DC  A "H2''" 1 
ATOM   441 H  "H1'"  . DC  A 1 14 ? 13.16373 -18.85915 15.57104  1.000 41.47402 ? 14  DC  A "H1'"  1 
ATOM   442 H  H41    . DC  A 1 14 ? 16.72701 -23.63478 12.95524  1.000 55.92187 ? 14  DC  A H41    1 
ATOM   443 H  H42    . DC  A 1 14 ? 15.33227 -23.94344 12.53308  1.000 55.92187 ? 14  DC  A H42    1 
ATOM   444 H  H5     . DC  A 1 14 ? 17.25106 -21.78737 14.49618  1.000 50.65645 ? 14  DC  A H5     1 
ATOM   445 H  H6     . DC  A 1 14 ? 16.37990 -20.06687 15.72653  1.000 48.23680 ? 14  DC  A H6     1 
ATOM   446 P  P      . DA  A 1 15 ? 12.52980 -16.63211 19.67656  1.000 51.30614 ? 15  DA  A P      1 
ATOM   447 O  OP1    . DA  A 1 15 ? 12.74264 -17.51488 20.83726  1.000 48.55073 ? 15  DA  A OP1    1 
ATOM   448 O  OP2    . DA  A 1 15 ? 11.27967 -15.85998 19.47223  1.000 55.30588 ? 15  DA  A OP2    1 
ATOM   449 O  "O5'"  . DA  A 1 15 ? 13.73558 -15.59516 19.67675  1.000 40.17011 ? 15  DA  A "O5'"  1 
ATOM   450 C  "C5'"  . DA  A 1 15 ? 13.49980 -14.30732 19.26000  1.000 36.18184 ? 15  DA  A "C5'"  1 
ATOM   451 C  "C4'"  . DA  A 1 15 ? 14.76982 -13.67146 18.76671  1.000 33.54316 ? 15  DA  A "C4'"  1 
ATOM   452 O  "O4'"  . DA  A 1 15 ? 15.30391 -14.40044 17.63486  1.000 31.38558 ? 15  DA  A "O4'"  1 
ATOM   453 C  "C3'"  . DA  A 1 15 ? 14.62476 -12.25668 18.28837  1.000 31.64928 ? 15  DA  A "C3'"  1 
ATOM   454 O  "O3'"  . DA  A 1 15 ? 15.83851 -11.59428 18.55461  1.000 33.09015 ? 15  DA  A "O3'"  1 
ATOM   455 C  "C2'"  . DA  A 1 15 ? 14.31106 -12.41918 16.80178  1.000 30.25738 ? 15  DA  A "C2'"  1 
ATOM   456 C  "C1'"  . DA  A 1 15 ? 15.06577 -13.69431 16.42683  1.000 28.74587 ? 15  DA  A "C1'"  1 
ATOM   457 N  N9     . DA  A 1 15 ? 14.37138 -14.64328 15.54844  1.000 32.37465 ? 15  DA  A N9     1 
ATOM   458 C  C8     . DA  A 1 15 ? 14.96540 -15.48687 14.65619  1.000 30.96618 ? 15  DA  A C8     1 
ATOM   459 N  N7     . DA  A 1 15 ? 14.13782 -16.30289 14.06355  1.000 28.44226 ? 15  DA  A N7     1 
ATOM   460 C  C5     . DA  A 1 15 ? 12.91442 -16.00079 14.62427  1.000 29.41699 ? 15  DA  A C5     1 
ATOM   461 C  C6     . DA  A 1 15 ? 11.63545 -16.52973 14.41818  1.000 32.70191 ? 15  DA  A C6     1 
ATOM   462 N  N6     . DA  A 1 15 ? 11.38762 -17.51709 13.56254  1.000 28.67242 ? 15  DA  A N6     1 
ATOM   463 N  N1     . DA  A 1 15 ? 10.61996 -16.00780 15.12539  1.000 38.06182 ? 15  DA  A N1     1 
ATOM   464 C  C2     . DA  A 1 15 ? 10.88372 -15.03134 16.00498  1.000 38.31581 ? 15  DA  A C2     1 
ATOM   465 N  N3     . DA  A 1 15 ? 12.04378 -14.46202 16.29298  1.000 35.19607 ? 15  DA  A N3     1 
ATOM   466 C  C4     . DA  A 1 15 ? 13.03309 -14.98796 15.54945  1.000 31.22295 ? 15  DA  A C4     1 
ATOM   467 H  "H5'"  . DA  A 1 15 ? 13.14850 -13.78945 20.00115  1.000 43.48027 ? 15  DA  A "H5'"  1 
ATOM   468 H  "H5''" . DA  A 1 15 ? 12.84619 -14.31656 18.54333  1.000 43.48027 ? 15  DA  A "H5''" 1 
ATOM   469 H  "H4'"  . DA  A 1 15 ? 15.42151 -13.70747 19.48428  1.000 40.31385 ? 15  DA  A "H4'"  1 
ATOM   470 H  "H3'"  . DA  A 1 15 ? 13.87774 -11.79281 18.69786  1.000 38.04119 ? 15  DA  A "H3'"  1 
ATOM   471 H  "H2'"  . DA  A 1 15 ? 13.35772 -12.51989 16.65380  1.000 36.37092 ? 15  DA  A "H2'"  1 
ATOM   472 H  "H2''" . DA  A 1 15 ? 14.63140 -11.65935 16.29096  1.000 36.37092 ? 15  DA  A "H2''" 1 
ATOM   473 H  "H1'"  . DA  A 1 15 ? 15.88611 -13.40327 15.99877  1.000 34.55711 ? 15  DA  A "H1'"  1 
ATOM   474 H  H8     . DA  A 1 15 ? 15.87956 -15.48086 14.48541  1.000 37.22148 ? 15  DA  A H8     1 
ATOM   475 H  H61    . DA  A 1 15 ? 10.58568 -17.81296 13.46793  1.000 34.46897 ? 15  DA  A H61    1 
ATOM   476 H  H62    . DA  A 1 15 ? 12.02930 -17.85975 13.10380  1.000 34.46897 ? 15  DA  A H62    1 
ATOM   477 H  H2     . DA  A 1 15 ? 10.15073 -14.70937 16.47822  1.000 46.04103 ? 15  DA  A H2     1 
ATOM   478 P  P      . DT  A 1 16 ? 16.08613 -10.08388 18.11466  1.000 40.92151 ? 16  DT  A P      1 
ATOM   479 O  OP1    . DT  A 1 16 ? 16.97829 -9.53980  19.16154  1.000 36.29217 ? 16  DT  A OP1    1 
ATOM   480 O  OP2    . DT  A 1 16 ? 14.79331 -9.43557  17.78022  1.000 41.21164 ? 16  DT  A OP2    1 
ATOM   481 O  "O5'"  . DT  A 1 16 ? 16.83330 -10.24494 16.73150  1.000 31.88524 ? 16  DT  A "O5'"  1 
ATOM   482 C  "C5'"  . DT  A 1 16 ? 18.03594 -10.91885 16.66175  1.000 29.44107 ? 16  DT  A "C5'"  1 
ATOM   483 C  "C4'"  . DT  A 1 16 ? 18.47161 -11.07009 15.22221  1.000 26.14260 ? 16  DT  A "C4'"  1 
ATOM   484 O  "O4'"  . DT  A 1 16 ? 17.55544 -11.94917 14.51224  1.000 29.34596 ? 16  DT  A "O4'"  1 
ATOM   485 C  "C3'"  . DT  A 1 16 ? 18.50564 -9.80072  14.39680  1.000 30.58810 ? 16  DT  A "C3'"  1 
ATOM   486 O  "O3'"  . DT  A 1 16 ? 19.60291 -9.90759  13.53146  1.000 25.36926 ? 16  DT  A "O3'"  1 
ATOM   487 C  "C2'"  . DT  A 1 16 ? 17.16162 -9.82235  13.66461  1.000 26.64379 ? 16  DT  A "C2'"  1 
ATOM   488 C  "C1'"  . DT  A 1 16 ? 17.05194 -11.29709 13.35796  1.000 26.00377 ? 16  DT  A "C1'"  1 
ATOM   489 N  N1     . DT  A 1 16 ? 15.68847 -11.83979 13.10384  1.000 25.93329 ? 16  DT  A N1     1 
ATOM   490 C  C2     . DT  A 1 16 ? 15.58423 -12.94356 12.31758  1.000 22.08196 ? 16  DT  A C2     1 
ATOM   491 O  O2     . DT  A 1 16 ? 16.53191 -13.43726 11.76998  1.000 24.37328 ? 16  DT  A O2     1 
ATOM   492 N  N3     . DT  A 1 16 ? 14.32747 -13.43007 12.15608  1.000 23.76972 ? 16  DT  A N3     1 
ATOM   493 C  C4     . DT  A 1 16 ? 13.18069 -12.95400 12.72887  1.000 26.46977 ? 16  DT  A C4     1 
ATOM   494 O  O4     . DT  A 1 16 ? 12.08370 -13.46932 12.54330  1.000 30.01149 ? 16  DT  A O4     1 
ATOM   495 C  C5     . DT  A 1 16 ? 13.35244 -11.81187 13.57388  1.000 31.77369 ? 16  DT  A C5     1 
ATOM   496 C  C7     . DT  A 1 16 ? 12.16344 -11.22252 14.24699  1.000 30.47632 ? 16  DT  A C7     1 
ATOM   497 C  C6     . DT  A 1 16 ? 14.59327 -11.30970 13.72942  1.000 28.65079 ? 16  DT  A C6     1 
ATOM   498 H  "H5'"  . DT  A 1 16 ? 17.93615 -11.79700 17.06150  1.000 35.39135 ? 16  DT  A "H5'"  1 
ATOM   499 H  "H5''" . DT  A 1 16 ? 18.71095 -10.42368 17.15171  1.000 35.39135 ? 16  DT  A "H5''" 1 
ATOM   500 H  "H4'"  . DT  A 1 16 ? 19.35821 -11.46357 15.22591  1.000 31.43318 ? 16  DT  A "H4'"  1 
ATOM   501 H  "H3'"  . DT  A 1 16 ? 18.54576 -8.99743  14.93903  1.000 36.76778 ? 16  DT  A "H3'"  1 
ATOM   502 H  "H2'"  . DT  A 1 16 ? 16.43617 -9.51555  14.23075  1.000 32.03460 ? 16  DT  A "H2'"  1 
ATOM   503 H  "H2''" . DT  A 1 16 ? 17.18080 -9.28530  12.85708  1.000 32.03460 ? 16  DT  A "H2''" 1 
ATOM   504 H  "H1'"  . DT  A 1 16 ? 17.58526 -11.47224 12.56690  1.000 31.26659 ? 16  DT  A "H1'"  1 
ATOM   505 H  H3     . DT  A 1 16 ? 14.24334 -14.11108 11.63767  1.000 28.58572 ? 16  DT  A H3     1 
ATOM   506 H  H71    . DT  A 1 16 ? 11.44202 -11.87088 14.23845  1.000 36.63364 ? 16  DT  A H71    1 
ATOM   507 H  H72    . DT  A 1 16 ? 12.39671 -10.99925 15.16167  1.000 36.63364 ? 16  DT  A H72    1 
ATOM   508 H  H73    . DT  A 1 16 ? 11.89457 -10.42218 13.76942  1.000 36.63364 ? 16  DT  A H73    1 
ATOM   509 H  H6     . DT  A 1 16 ? 14.70987 -10.57278 14.28463  1.000 34.44301 ? 16  DT  A H6     1 
ATOM   510 P  P      . DA  A 1 17 ? 19.99269 -8.74445  12.51031  1.000 23.20242 ? 17  DA  A P      1 
ATOM   511 O  OP1    . DA  A 1 17 ? 21.47998 -8.58745  12.51883  1.000 26.12808 ? 17  DA  A OP1    1 
ATOM   512 O  OP2    . DA  A 1 17 ? 19.15706 -7.54357  12.71326  1.000 23.62374 ? 17  DA  A OP2    1 
ATOM   513 O  "O5'"  . DA  A 1 17 ? 19.55038 -9.42211  11.14015  1.000 25.75984 ? 17  DA  A "O5'"  1 
ATOM   514 C  "C5'"  . DA  A 1 17 ? 20.21505 -10.56534 10.63752  1.000 23.40149 ? 17  DA  A "C5'"  1 
ATOM   515 C  "C4'"  . DA  A 1 17 ? 20.35901 -10.45623 9.12086   1.000 21.38946 ? 17  DA  A "C4'"  1 
ATOM   516 O  "O4'"  . DA  A 1 17 ? 19.06595 -10.66810 8.45611   1.000 22.12833 ? 17  DA  A "O4'"  1 
ATOM   517 C  "C3'"  . DA  A 1 17 ? 20.80642 -9.08669  8.63317   1.000 18.43629 ? 17  DA  A "C3'"  1 
ATOM   518 O  "O3'"  . DA  A 1 17 ? 21.64218 -9.22492  7.52090   1.000 22.05724 ? 17  DA  A "O3'"  1 
ATOM   519 C  "C2'"  . DA  A 1 17 ? 19.49505 -8.42377  8.26344   1.000 19.51137 ? 17  DA  A "C2'"  1 
ATOM   520 C  "C1'"  . DA  A 1 17 ? 18.82520 -9.57319  7.58089   1.000 20.34737 ? 17  DA  A "C1'"  1 
ATOM   521 N  N9     . DA  A 1 17 ? 17.41019 -9.42523  7.40342   1.000 20.50712 ? 17  DA  A N9     1 
ATOM   522 C  C8     . DA  A 1 17 ? 16.61408 -8.43552  7.88949   1.000 20.93486 ? 17  DA  A C8     1 
ATOM   523 N  N7     . DA  A 1 17 ? 15.35165 -8.58501  7.59453   1.000 24.13128 ? 17  DA  A N7     1 
ATOM   524 C  C5     . DA  A 1 17 ? 15.32454 -9.74617  6.84713   1.000 20.59144 ? 17  DA  A C5     1 
ATOM   525 C  C6     . DA  A 1 17 ? 14.28332 -10.45849 6.22828   1.000 18.98178 ? 17  DA  A C6     1 
ATOM   526 N  N6     . DA  A 1 17 ? 13.00771 -10.08030 6.28753   1.000 23.58724 ? 17  DA  A N6     1 
ATOM   527 N  N1     . DA  A 1 17 ? 14.60100 -11.57986 5.55567   1.000 16.98875 ? 17  DA  A N1     1 
ATOM   528 C  C2     . DA  A 1 17 ? 15.87331 -11.96579 5.51799   1.000 22.65212 ? 17  DA  A C2     1 
ATOM   529 N  N3     . DA  A 1 17 ? 16.94004 -11.37723 6.05668   1.000 20.31317 ? 17  DA  A N3     1 
ATOM   530 C  C4     . DA  A 1 17 ? 16.59090 -10.27074 6.71648   1.000 20.39779 ? 17  DA  A C4     1 
ATOM   531 H  "H5'"  . DA  A 1 17 ? 19.70413 -11.35989 10.85789  1.000 28.14385 ? 17  DA  A "H5'"  1 
ATOM   532 H  "H5''" . DA  A 1 17 ? 21.09405 -10.63281 11.04212  1.000 28.14385 ? 17  DA  A "H5''" 1 
ATOM   533 H  "H4'"  . DA  A 1 17 ? 20.97548 -11.14475 8.82622   1.000 25.72941 ? 17  DA  A "H4'"  1 
ATOM   534 H  "H3'"  . DA  A 1 17 ? 21.25146 -8.59720  9.34257   1.000 22.18560 ? 17  DA  A "H3'"  1 
ATOM   535 H  "H2'"  . DA  A 1 17 ? 19.00334 -8.12741  9.04530   1.000 23.47570 ? 17  DA  A "H2'"  1 
ATOM   536 H  "H2''" . DA  A 1 17 ? 19.62329 -7.66998  7.66658   1.000 23.47570 ? 17  DA  A "H2''" 1 
ATOM   537 H  "H1'"  . DA  A 1 17 ? 19.21503 -9.72354  6.70549   1.000 24.47890 ? 17  DA  A "H1'"  1 
ATOM   538 H  H8     . DA  A 1 17 ? 16.93895 -7.71917  8.38567   1.000 25.18389 ? 17  DA  A H8     1 
ATOM   539 H  H61    . DA  A 1 17 ? 12.40130 -10.55060 5.89936   1.000 28.36675 ? 17  DA  A H61    1 
ATOM   540 H  H62    . DA  A 1 17 ? 12.79042 -9.36578  6.71397   1.000 28.36675 ? 17  DA  A H62    1 
ATOM   541 H  H2     . DA  A 1 17 ? 16.04089 -12.75326 5.05248   1.000 27.24461 ? 17  DA  A H2     1 
ATOM   542 P  P      . DG  A 1 18 ? 23.23874 -9.22747  7.67125   1.000 23.02538 ? 18  DG  A P      1 
ATOM   543 O  OP1    . DG  A 1 18 ? 23.68400 -10.30424 8.60365   1.000 22.78995 ? 18  DG  A OP1    1 
ATOM   544 O  OP2    . DG  A 1 18 ? 23.66893 -7.84482  7.92118   1.000 21.66895 ? 18  DG  A OP2    1 
ATOM   545 O  "O5'"  . DG  A 1 18 ? 23.71706 -9.63340  6.20981   1.000 21.37493 ? 18  DG  A "O5'"  1 
ATOM   546 C  "C5'"  . DG  A 1 18 ? 23.50454 -10.95146 5.75754   1.000 21.33605 ? 18  DG  A "C5'"  1 
ATOM   547 C  "C4'"  . DG  A 1 18 ? 22.86728 -10.94488 4.40610   1.000 17.32283 ? 18  DG  A "C4'"  1 
ATOM   548 O  "O4'"  . DG  A 1 18 ? 21.46536 -10.57568 4.54074   1.000 19.09287 ? 18  DG  A "O4'"  1 
ATOM   549 C  "C3'"  . DG  A 1 18 ? 23.46638 -9.91891  3.44383   1.000 19.31823 ? 18  DG  A "C3'"  1 
ATOM   550 O  "O3'"  . DG  A 1 18 ? 23.58095 -10.42387 2.13914   1.000 22.53239 ? 18  DG  A "O3'"  1 
ATOM   551 C  "C2'"  . DG  A 1 18 ? 22.45474 -8.81790  3.47259   1.000 18.43182 ? 18  DG  A "C2'"  1 
ATOM   552 C  "C1'"  . DG  A 1 18 ? 21.19018 -9.63269  3.54816   1.000 19.32546 ? 18  DG  A "C1'"  1 
ATOM   553 N  N9     . DG  A 1 18 ? 20.00970 -8.87113  3.88823   1.000 19.97170 ? 18  DG  A N9     1 
ATOM   554 C  C8     . DG  A 1 18 ? 19.96815 -7.68045  4.56489   1.000 23.32635 ? 18  DG  A C8     1 
ATOM   555 N  N7     . DG  A 1 18 ? 18.76427 -7.21329  4.70509   1.000 23.07938 ? 18  DG  A N7     1 
ATOM   556 C  C5     . DG  A 1 18 ? 17.96296 -8.14113  4.07376   1.000 19.94207 ? 18  DG  A C5     1 
ATOM   557 C  C6     . DG  A 1 18 ? 16.56598 -8.16514  3.90911   1.000 22.68599 ? 18  DG  A C6     1 
ATOM   558 O  O6     . DG  A 1 18 ? 15.72493 -7.33140  4.31565   1.000 23.68484 ? 18  DG  A O6     1 
ATOM   559 N  N1     . DG  A 1 18 ? 16.15049 -9.29762  3.21259   1.000 22.06886 ? 18  DG  A N1     1 
ATOM   560 C  C2     . DG  A 1 18 ? 16.97794 -10.27915 2.75379   1.000 20.69480 ? 18  DG  A C2     1 
ATOM   561 N  N2     . DG  A 1 18 ? 16.39087 -11.29709 2.11951   1.000 22.49269 ? 18  DG  A N2     1 
ATOM   562 N  N3     . DG  A 1 18 ? 18.29380 -10.25975 2.89280   1.000 19.95217 ? 18  DG  A N3     1 
ATOM   563 C  C4     . DG  A 1 18 ? 18.71586 -9.16234  3.55285   1.000 19.04028 ? 18  DG  A C4     1 
ATOM   564 H  "H5'"  . DG  A 1 18 ? 22.92652 -11.41611 6.38276   1.000 25.66532 ? 18  DG  A "H5'"  1 
ATOM   565 H  "H5''" . DG  A 1 18 ? 24.35506 -11.41532 5.70915   1.000 25.66532 ? 18  DG  A "H5''" 1 
ATOM   566 H  "H4'"  . DG  A 1 18 ? 22.92174 -11.83009 4.01324   1.000 20.47709 ? 18  DG  A "H4'"  1 
ATOM   567 H  "H3'"  . DG  A 1 18 ? 24.33173 -9.64023  3.78205   1.000 23.24393 ? 18  DG  A "H3'"  1 
ATOM   568 H  "H2'"  . DG  A 1 18 ? 22.56401 -8.24505  4.24770   1.000 21.80788 ? 18  DG  A "H2'"  1 
ATOM   569 H  "H2''" . DG  A 1 18 ? 22.48812 -8.27358  2.67040   1.000 21.80788 ? 18  DG  A "H2''" 1 
ATOM   570 H  "H1'"  . DG  A 1 18 ? 21.00402 -10.07572 2.70556   1.000 23.25261 ? 18  DG  A "H1'"  1 
ATOM   571 H  H8     . DG  A 1 18 ? 20.72544 -7.25018  4.89090   1.000 28.05368 ? 18  DG  A H8     1 
ATOM   572 H  H1     . DG  A 1 18 ? 15.30848 -9.38416  3.06051   1.000 26.54469 ? 18  DG  A H1     1 
ATOM   573 H  H21    . DG  A 1 18 ? 15.53584 -11.31124 2.02831   1.000 27.05328 ? 18  DG  A H21    1 
ATOM   574 H  H22    . DG  A 1 18 ? 16.86782 -11.93853 1.80221   1.000 27.05328 ? 18  DG  A H22    1 
ATOM   575 P  P      . DG  A 1 19 ? 25.00072 -10.85446 1.56977   1.000 25.73952 ? 19  DG  A P      1 
ATOM   576 O  OP1    . DG  A 1 19 ? 25.47546 -11.71849 2.66093   1.000 24.40517 ? 19  DG  A OP1    1 
ATOM   577 O  OP2    . DG  A 1 19 ? 25.83397 -9.70979  1.14909   1.000 27.40848 ? 19  DG  A OP2    1 
ATOM   578 O  "O5'"  . DG  A 1 19 ? 24.62070 -11.77131 0.32603   1.000 22.97039 ? 19  DG  A "O5'"  1 
ATOM   579 C  "C5'"  . DG  A 1 19 ? 23.79486 -12.89663 0.55991   1.000 25.19283 ? 19  DG  A "C5'"  1 
ATOM   580 C  "C4'"  . DG  A 1 19 ? 22.82652 -13.10291 -0.56231  1.000 29.76703 ? 19  DG  A "C4'"  1 
ATOM   581 O  "O4'"  . DG  A 1 19 ? 21.65086 -12.28243 -0.34504  1.000 29.48475 ? 19  DG  A "O4'"  1 
ATOM   582 C  "C3'"  . DG  A 1 19 ? 23.34429 -12.72686 -1.94060  1.000 28.76045 ? 19  DG  A "C3'"  1 
ATOM   583 O  "O3'"  . DG  A 1 19 ? 22.83335 -13.62440 -2.88439  1.000 24.87246 ? 19  DG  A "O3'"  1 
ATOM   584 C  "C2'"  . DG  A 1 19 ? 22.81665 -11.31038 -2.12966  1.000 22.83867 ? 19  DG  A "C2'"  1 
ATOM   585 C  "C1'"  . DG  A 1 19 ? 21.46319 -11.40019 -1.43096  1.000 25.07771 ? 19  DG  A "C1'"  1 
ATOM   586 N  N9     . DG  A 1 19 ? 20.92937 -10.17212 -0.86701  1.000 21.54565 ? 19  DG  A N9     1 
ATOM   587 C  C8     . DG  A 1 19 ? 21.60997 -9.13106  -0.29405  1.000 22.69111 ? 19  DG  A C8     1 
ATOM   588 N  N7     . DG  A 1 19 ? 20.82010 -8.20458  0.17976   1.000 21.70284 ? 19  DG  A N7     1 
ATOM   589 C  C5     . DG  A 1 19 ? 19.53917 -8.69569  -0.06923  1.000 19.89715 ? 19  DG  A C5     1 
ATOM   590 C  C6     . DG  A 1 19 ? 18.26841 -8.13741  0.20423   1.000 25.18593 ? 19  DG  A C6     1 
ATOM   591 O  O6     . DG  A 1 19 ? 17.99529 -7.05870  0.74329   1.000 24.75000 ? 19  DG  A O6     1 
ATOM   592 N  N1     . DG  A 1 19 ? 17.24177 -8.95942  -0.24254  1.000 22.82259 ? 19  DG  A N1     1 
ATOM   593 C  C2     . DG  A 1 19 ? 17.42661 -10.15949 -0.87876  1.000 25.36601 ? 19  DG  A C2     1 
ATOM   594 N  N2     . DG  A 1 19 ? 16.32276 -10.82848 -1.23217  1.000 24.91944 ? 19  DG  A N2     1 
ATOM   595 N  N3     . DG  A 1 19 ? 18.61000 -10.68241 -1.13937  1.000 20.19261 ? 19  DG  A N3     1 
ATOM   596 C  C4     . DG  A 1 19 ? 19.60965 -9.89207  -0.71704  1.000 18.58271 ? 19  DG  A C4     1 
ATOM   597 H  "H5'"  . DG  A 1 19 ? 23.30190 -12.76320 1.38459   1.000 30.29346 ? 19  DG  A "H5'"  1 
ATOM   598 H  "H5''" . DG  A 1 19 ? 24.35124 -13.68621 0.64880   1.000 30.29346 ? 19  DG  A "H5''" 1 
ATOM   599 H  "H4'"  . DG  A 1 19 ? 22.55735 -14.03470 -0.57686  1.000 35.78249 ? 19  DG  A "H4'"  1 
ATOM   600 H  "H3'"  . DG  A 1 19 ? 24.31393 -12.71595 -1.96480  1.000 34.57460 ? 19  DG  A "H3'"  1 
ATOM   601 H  "H2'"  . DG  A 1 19 ? 23.39377 -10.65491 -1.70753  1.000 27.46846 ? 19  DG  A "H2'"  1 
ATOM   602 H  "H2''" . DG  A 1 19 ? 22.71978 -11.08765 -3.06876  1.000 27.46846 ? 19  DG  A "H2''" 1 
ATOM   603 H  "H1'"  . DG  A 1 19 ? 20.83094 -11.73768 -2.08461  1.000 30.15532 ? 19  DG  A "H1'"  1 
ATOM   604 H  H8     . DG  A 1 19 ? 22.53779 -9.08807  -0.24712  1.000 27.29139 ? 19  DG  A H8     1 
ATOM   605 H  H1     . DG  A 1 19 ? 16.43343 -8.69707  -0.11077  1.000 27.44917 ? 19  DG  A H1     1 
ATOM   606 H  H21    . DG  A 1 19 ? 16.38912 -11.59077 -1.62474  1.000 29.96539 ? 19  DG  A H21    1 
ATOM   607 H  H22    . DG  A 1 19 ? 15.54704 -10.49611 -1.06671  1.000 29.96539 ? 19  DG  A H22    1 
ATOM   608 P  P      . DC  A 1 20 ? 23.54896 -13.81204 -4.28319  1.000 29.29000 ? 20  DC  A P      1 
ATOM   609 O  OP1    . DC  A 1 20 ? 24.32921 -12.59392 -4.61218  1.000 29.30576 ? 20  DC  A OP1    1 
ATOM   610 O  OP2    . DC  A 1 20 ? 22.48132 -14.26871 -5.20720  1.000 31.14570 ? 20  DC  A OP2    1 
ATOM   611 O  "O5'"  . DC  A 1 20 ? 24.62168 -14.97254 -4.02043  1.000 30.48454 ? 20  DC  A "O5'"  1 
ATOM   612 C  "C5'"  . DC  A 1 20 ? 24.27094 -16.35111 -4.17617  1.000 28.64742 ? 20  DC  A "C5'"  1 
ATOM   613 C  "C4'"  . DC  A 1 20 ? 24.56665 -17.14569 -2.91850  1.000 33.60262 ? 20  DC  A "C4'"  1 
ATOM   614 O  "O4'"  . DC  A 1 20 ? 25.89469 -16.84181 -2.40956  1.000 29.07277 ? 20  DC  A "O4'"  1 
ATOM   615 C  "C3'"  . DC  A 1 20 ? 23.62132 -16.86321 -1.78073  1.000 32.24308 ? 20  DC  A "C3'"  1 
ATOM   616 O  "O3'"  . DC  A 1 20 ? 22.52385 -17.71407 -1.90880  1.000 32.56458 ? 20  DC  A "O3'"  1 
ATOM   617 C  "C2'"  . DC  A 1 20 ? 24.46243 -17.14402 -0.53054  1.000 30.67777 ? 20  DC  A "C2'"  1 
ATOM   618 C  "C1'"  . DC  A 1 20 ? 25.90194 -16.90177 -0.99826  1.000 30.85511 ? 20  DC  A "C1'"  1 
ATOM   619 N  N1     . DC  A 1 20 ? 26.51319 -15.64296 -0.53083  1.000 32.94129 ? 20  DC  A N1     1 
ATOM   620 C  C2     . DC  A 1 20 ? 27.03197 -15.54840 0.76054   1.000 27.80274 ? 20  DC  A C2     1 
ATOM   621 O  O2     . DC  A 1 20 ? 26.92897 -16.51619 1.51447   1.000 36.40475 ? 20  DC  A O2     1 
ATOM   622 N  N3     . DC  A 1 20 ? 27.61797 -14.39570 1.14831   1.000 25.16034 ? 20  DC  A N3     1 
ATOM   623 C  C4     . DC  A 1 20 ? 27.72192 -13.37551 0.28699   1.000 30.88170 ? 20  DC  A C4     1 
ATOM   624 N  N4     . DC  A 1 20 ? 28.31154 -12.25160 0.69868   1.000 36.07824 ? 20  DC  A N4     1 
ATOM   625 C  C5     . DC  A 1 20 ? 27.22852 -13.46841 -1.04179  1.000 33.37874 ? 20  DC  A C5     1 
ATOM   626 C  C6     . DC  A 1 20 ? 26.64958 -14.61612 -1.40818  1.000 33.72455 ? 20  DC  A C6     1 
ATOM   627 H  "H5'"  . DC  A 1 20 ? 24.77712 -16.72556 -4.91404  1.000 34.43896 ? 20  DC  A "H5'"  1 
ATOM   628 H  "H5''" . DC  A 1 20 ? 23.32426 -16.41657 -4.37722  1.000 34.43896 ? 20  DC  A "H5''" 1 
ATOM   629 H  "H4'"  . DC  A 1 20 ? 24.55126 -18.09062 -3.13706  1.000 40.38520 ? 20  DC  A "H4'"  1 
ATOM   630 H  "H3'"  . DC  A 1 20 ? 23.34736 -15.93294 -1.75962  1.000 38.75375 ? 20  DC  A "H3'"  1 
ATOM   631 H  "H2'"  . DC  A 1 20 ? 24.22503 -16.54084 0.19107   1.000 36.87538 ? 20  DC  A "H2'"  1 
ATOM   632 H  "H2''" . DC  A 1 20 ? 24.34373 -18.05851 -0.22968  1.000 36.87538 ? 20  DC  A "H2''" 1 
ATOM   633 H  "H1'"  . DC  A 1 20 ? 26.42499 -17.65941 -0.69280  1.000 37.08819 ? 20  DC  A "H1'"  1 
ATOM   634 H  H41    . DC  A 1 20 ? 28.38848 -11.58462 0.16126   1.000 43.35594 ? 20  DC  A H41    1 
ATOM   635 H  H42    . DC  A 1 20 ? 28.61464 -12.19417 1.50144   1.000 43.35594 ? 20  DC  A H42    1 
ATOM   636 H  H5     . DC  A 1 20 ? 27.30549 -12.75655 -1.63528  1.000 40.11655 ? 20  DC  A H5     1 
ATOM   637 H  H6     . DC  A 1 20 ? 26.33519 -14.71272 -2.27808  1.000 40.53152 ? 20  DC  A H6     1 
ATOM   638 P  P      . DG  A 1 21 ? 21.07501 -17.32405 -1.34177  1.000 29.10397 ? 21  DG  A P      1 
ATOM   639 O  OP1    . DG  A 1 21 ? 20.10616 -17.57076 -2.43924  1.000 28.84865 ? 21  DG  A OP1    1 
ATOM   640 O  OP2    . DG  A 1 21 ? 21.02538 -16.00795 -0.64719  1.000 26.68342 ? 21  DG  A OP2    1 
ATOM   641 O  "O5'"  . DG  A 1 21 ? 20.86730 -18.45219 -0.26733  1.000 27.26539 ? 21  DG  A "O5'"  1 
ATOM   642 C  "C5'"  . DG  A 1 21 ? 21.25358 -19.77005 -0.56027  1.000 25.23065 ? 21  DG  A "C5'"  1 
ATOM   643 C  "C4'"  . DG  A 1 21 ? 20.14050 -20.71320 -0.19905  1.000 20.25845 ? 21  DG  A "C4'"  1 
ATOM   644 O  "O4'"  . DG  A 1 21 ? 19.82526 -20.54332 1.20600   1.000 23.17578 ? 21  DG  A "O4'"  1 
ATOM   645 C  "C3'"  . DG  A 1 21 ? 18.85973 -20.44795 -0.95010  1.000 24.00573 ? 21  DG  A "C3'"  1 
ATOM   646 O  "O3'"  . DG  A 1 21 ? 18.72064 -21.36099 -2.01965  1.000 24.56582 ? 21  DG  A "O3'"  1 
ATOM   647 C  "C2'"  . DG  A 1 21 ? 17.75562 -20.59993 0.07781   1.000 25.19207 ? 21  DG  A "C2'"  1 
ATOM   648 C  "C1'"  . DG  A 1 21 ? 18.44102 -20.44084 1.39404   1.000 24.13722 ? 21  DG  A "C1'"  1 
ATOM   649 N  N9     . DG  A 1 21 ? 18.16570 -19.18834 2.05809   1.000 24.95134 ? 21  DG  A N9     1 
ATOM   650 C  C8     . DG  A 1 21 ? 19.06394 -18.23119 2.42025   1.000 25.54564 ? 21  DG  A C8     1 
ATOM   651 N  N7     . DG  A 1 21 ? 18.52794 -17.24309 3.06485   1.000 26.96102 ? 21  DG  A N7     1 
ATOM   652 C  C5     . DG  A 1 21 ? 17.19439 -17.59244 3.15523   1.000 24.80354 ? 21  DG  A C5     1 
ATOM   653 C  C6     . DG  A 1 21 ? 16.11786 -16.91817 3.76286   1.000 24.72985 ? 21  DG  A C6     1 
ATOM   654 O  O6     . DG  A 1 21 ? 16.12908 -15.84166 4.36597   1.000 19.99450 ? 21  DG  A O6     1 
ATOM   655 N  N1     . DG  A 1 21 ? 14.92717 -17.62226 3.61796   1.000 25.09935 ? 21  DG  A N1     1 
ATOM   656 C  C2     . DG  A 1 21 ? 14.81105 -18.81846 2.96811   1.000 21.89952 ? 21  DG  A C2     1 
ATOM   657 N  N2     . DG  A 1 21 ? 13.58372 -19.33893 2.90480   1.000 25.49758 ? 21  DG  A N2     1 
ATOM   658 N  N3     . DG  A 1 21 ? 15.81825 -19.45462 2.40531   1.000 26.43542 ? 21  DG  A N3     1 
ATOM   659 C  C4     . DG  A 1 21 ? 16.96819 -18.79460 2.55147   1.000 19.69049 ? 21  DG  A C4     1 
ATOM   660 H  "H5'"  . DG  A 1 21 ? 22.04846 -19.99603 -0.05234  1.000 30.33884 ? 21  DG  A "H5'"  1 
ATOM   661 H  "H5''" . DG  A 1 21 ? 21.45091 -19.84788 -1.50679  1.000 30.33884 ? 21  DG  A "H5''" 1 
ATOM   662 H  "H4'"  . DG  A 1 21 ? 20.41258 -21.63272 -0.34518  1.000 23.99984 ? 21  DG  A "H4'"  1 
ATOM   663 H  "H3'"  . DG  A 1 21 ? 18.86453 -19.53158 -1.26815  1.000 28.86894 ? 21  DG  A "H3'"  1 
ATOM   664 H  "H2'"  . DG  A 1 21 ? 17.07733 -19.91693 -0.04194  1.000 30.29254 ? 21  DG  A "H2'"  1 
ATOM   665 H  "H2''" . DG  A 1 21 ? 17.33961 -21.47353 0.00963   1.000 30.29254 ? 21  DG  A "H2''" 1 
ATOM   666 H  "H1'"  . DG  A 1 21 ? 18.16117 -21.18211 1.95359   1.000 29.02673 ? 21  DG  A "H1'"  1 
ATOM   667 H  H8     . DG  A 1 21 ? 19.97170 -18.28160 2.22448   1.000 30.71683 ? 21  DG  A H8     1 
ATOM   668 H  H1     . DG  A 1 21 ? 14.21579 -17.28156 3.96067   1.000 30.18128 ? 21  DG  A H1     1 
ATOM   669 H  H21    . DG  A 1 21 ? 13.45372 -20.08555 2.49830   1.000 30.65916 ? 21  DG  A H21    1 
ATOM   670 H  H22    . DG  A 1 21 ? 12.92287 -18.92767 3.27051   1.000 30.65916 ? 21  DG  A H22    1 
ATOM   671 P  P      . DT  A 1 22 ? 17.81534 -20.96207 -3.27623  1.000 25.86010 ? 22  DT  A P      1 
ATOM   672 O  OP1    . DT  A 1 22 ? 17.98833 -21.99805 -4.33741  1.000 27.98066 ? 22  DT  A OP1    1 
ATOM   673 O  OP2    . DT  A 1 22 ? 18.25687 -19.58705 -3.60925  1.000 23.44537 ? 22  DT  A OP2    1 
ATOM   674 O  "O5'"  . DT  A 1 22 ? 16.32470 -20.86546 -2.68112  1.000 26.48547 ? 22  DT  A "O5'"  1 
ATOM   675 C  "C5'"  . DT  A 1 22 ? 15.64885 -22.00732 -2.24220  1.000 21.39843 ? 22  DT  A "C5'"  1 
ATOM   676 C  "C4'"  . DT  A 1 22 ? 14.19273 -21.71849 -1.97421  1.000 21.09302 ? 22  DT  A "C4'"  1 
ATOM   677 O  "O4'"  . DT  A 1 22 ? 14.07186 -20.73792 -0.91898  1.000 25.56191 ? 22  DT  A "O4'"  1 
ATOM   678 C  "C3'"  . DT  A 1 22 ? 13.43679 -21.14949 -3.15460  1.000 24.18465 ? 22  DT  A "C3'"  1 
ATOM   679 O  "O3'"  . DT  A 1 22 ? 12.18598 -21.72364 -3.23093  1.000 27.20602 ? 22  DT  A "O3'"  1 
ATOM   680 C  "C2'"  . DT  A 1 22 ? 13.36487 -19.66165 -2.86492  1.000 24.41886 ? 22  DT  A "C2'"  1 
ATOM   681 C  "C1'"  . DT  A 1 22 ? 13.30995 -19.62900 -1.35943  1.000 27.17590 ? 22  DT  A "C1'"  1 
ATOM   682 N  N1     . DT  A 1 22 ? 13.89141 -18.42197 -0.72872  1.000 22.24659 ? 22  DT  A N1     1 
ATOM   683 C  C2     . DT  A 1 22 ? 13.10720 -17.65136 0.08458   1.000 21.88368 ? 22  DT  A C2     1 
ATOM   684 O  O2     . DT  A 1 22 ? 11.95208 -17.86087 0.27497   1.000 22.89736 ? 22  DT  A O2     1 
ATOM   685 N  N3     . DT  A 1 22 ? 13.72613 -16.61187 0.66399   1.000 20.28041 ? 22  DT  A N3     1 
ATOM   686 C  C4     . DT  A 1 22 ? 15.03649 -16.25809 0.56204   1.000 22.84099 ? 22  DT  A C4     1 
ATOM   687 O  O4     . DT  A 1 22 ? 15.48194 -15.28607 1.15226   1.000 19.37583 ? 22  DT  A O4     1 
ATOM   688 C  C5     . DT  A 1 22 ? 15.83561 -17.11173 -0.30315  1.000 22.58320 ? 22  DT  A C5     1 
ATOM   689 C  C7     . DT  A 1 22 ? 17.30691 -16.83624 -0.53263  1.000 25.27749 ? 22  DT  A C7     1 
ATOM   690 C  C6     . DT  A 1 22 ? 15.22125 -18.15400 -0.88426  1.000 23.08950 ? 22  DT  A C6     1 
ATOM   691 H  "H5'"  . DT  A 1 22 ? 16.06405 -22.32750 -1.42612  1.000 25.74018 ? 22  DT  A "H5'"  1 
ATOM   692 H  "H5''" . DT  A 1 22 ? 15.71563 -22.69620 -2.92182  1.000 25.74018 ? 22  DT  A "H5''" 1 
ATOM   693 H  "H4'"  . DT  A 1 22 ? 13.75703 -22.53410 -1.68123  1.000 25.37368 ? 22  DT  A "H4'"  1 
ATOM   694 H  "H3'"  . DT  A 1 22 ? 13.93873 -21.29413 -3.97194  1.000 29.08364 ? 22  DT  A "H3'"  1 
ATOM   695 H  "H2'"  . DT  A 1 22 ? 14.14848 -19.19834 -3.19989  1.000 29.36469 ? 22  DT  A "H2'"  1 
ATOM   696 H  "H2''" . DT  A 1 22 ? 12.57144 -19.26364 -3.25601  1.000 29.36469 ? 22  DT  A "H2''" 1 
ATOM   697 H  "H1'"  . DT  A 1 22 ? 12.38157 -19.70814 -1.08972  1.000 32.67314 ? 22  DT  A "H1'"  1 
ATOM   698 H  H3     . DT  A 1 22 ? 13.23591 -16.10826 1.15963   1.000 24.39855 ? 22  DT  A H3     1 
ATOM   699 H  H71    . DT  A 1 22 ? 17.44195 -16.59628 -1.46272  1.000 30.39505 ? 22  DT  A H71    1 
ATOM   700 H  H72    . DT  A 1 22 ? 17.58457 -16.10519 0.04127   1.000 30.39505 ? 22  DT  A H72    1 
ATOM   701 H  H73    . DT  A 1 22 ? 17.81465 -17.63492 -0.31999  1.000 30.39505 ? 22  DT  A H73    1 
ATOM   702 H  H6     . DT  A 1 22 ? 15.72663 -18.72216 -1.41969  1.000 27.76946 ? 22  DT  A H6     1 
ATOM   703 P  P      . DC  A 1 23 ? 11.29352 -21.51431 -4.53699  1.000 29.32521 ? 23  DC  A P      1 
ATOM   704 O  OP1    . DC  A 1 23 ? 10.47277 -22.73373 -4.57652  1.000 34.36771 ? 23  DC  A OP1    1 
ATOM   705 O  OP2    . DC  A 1 23 ? 12.12825 -21.06807 -5.68598  1.000 30.21122 ? 23  DC  A OP2    1 
ATOM   706 O  "O5'"  . DC  A 1 23 ? 10.42597 -20.21953 -4.17629  1.000 28.45265 ? 23  DC  A "O5'"  1 
ATOM   707 C  "C5'"  . DC  A 1 23 ? 9.54187  -20.24161 -3.10342  1.000 28.76303 ? 23  DC  A "C5'"  1 
ATOM   708 C  "C4'"  . DC  A 1 23 ? 9.03720  -18.85542 -2.81817  1.000 27.74102 ? 23  DC  A "C4'"  1 
ATOM   709 O  "O4'"  . DC  A 1 23 ? 10.09229 -18.06730 -2.25513  1.000 27.09267 ? 23  DC  A "O4'"  1 
ATOM   710 C  "C3'"  . DC  A 1 23 ? 8.59022  -18.07268 -4.04666  1.000 26.48220 ? 23  DC  A "C3'"  1 
ATOM   711 O  "O3'"  . DC  A 1 23 ? 7.20168  -18.11961 -4.18116  1.000 31.76092 ? 23  DC  A "O3'"  1 
ATOM   712 C  "C2'"  . DC  A 1 23 ? 9.11447  -16.64376 -3.79652  1.000 31.01290 ? 23  DC  A "C2'"  1 
ATOM   713 C  "C1'"  . DC  A 1 23 ? 9.71880  -16.72990 -2.39893  1.000 28.95809 ? 23  DC  A "C1'"  1 
ATOM   714 N  N1     . DC  A 1 23 ? 10.90773 -15.89346 -2.15761  1.000 23.77415 ? 23  DC  A N1     1 
ATOM   715 C  C2     . DC  A 1 23 ? 10.82034 -14.79826 -1.27793  1.000 22.32831 ? 23  DC  A C2     1 
ATOM   716 O  O2     . DC  A 1 23 ? 9.74747  -14.50916 -0.78826  1.000 23.17211 ? 23  DC  A O2     1 
ATOM   717 N  N3     . DC  A 1 23 ? 11.90583 -14.06366 -1.03340  1.000 22.82355 ? 23  DC  A N3     1 
ATOM   718 C  C4     . DC  A 1 23 ? 13.05204 -14.39374 -1.57788  1.000 22.86485 ? 23  DC  A C4     1 
ATOM   719 N  N4     . DC  A 1 23 ? 14.09957 -13.64158 -1.29220  1.000 22.71736 ? 23  DC  A N4     1 
ATOM   720 C  C5     . DC  A 1 23 ? 13.18180 -15.51021 -2.46321  1.000 24.33942 ? 23  DC  A C5     1 
ATOM   721 C  C6     . DC  A 1 23 ? 12.08877 -16.23178 -2.70705  1.000 22.72256 ? 23  DC  A C6     1 
ATOM   722 H  "H5'"  . DC  A 1 23 ? 9.99576  -20.58710 -2.31887  1.000 34.57769 ? 23  DC  A "H5'"  1 
ATOM   723 H  "H5''" . DC  A 1 23 ? 8.79260  -20.82011 -3.31514  1.000 34.57769 ? 23  DC  A "H5''" 1 
ATOM   724 H  "H4'"  . DC  A 1 23 ? 8.30506  -18.91580 -2.18475  1.000 33.35129 ? 23  DC  A "H4'"  1 
ATOM   725 H  "H3'"  . DC  A 1 23 ? 9.01923  -18.43496 -4.83761  1.000 31.84070 ? 23  DC  A "H3'"  1 
ATOM   726 H  "H2'"  . DC  A 1 23 ? 9.78533  -16.39799 -4.45260  1.000 37.27754 ? 23  DC  A "H2'"  1 
ATOM   727 H  "H2''" . DC  A 1 23 ? 8.39240  -15.99671 -3.82556  1.000 37.27754 ? 23  DC  A "H2''" 1 
ATOM   728 H  "H1'"  . DC  A 1 23 ? 9.04470  -16.47369 -1.75021  1.000 34.81177 ? 23  DC  A "H1'"  1 
ATOM   729 H  H41    . DC  A 1 23 ? 14.86779 -13.82768 -1.63101  1.000 27.32289 ? 23  DC  A H41    1 
ATOM   730 H  H42    . DC  A 1 23 ? 14.01338 -12.96576 -0.76738  1.000 27.32289 ? 23  DC  A H42    1 
ATOM   731 H  H5     . DC  A 1 23 ? 13.99830 -15.72410 -2.85369  1.000 29.26937 ? 23  DC  A H5     1 
ATOM   732 H  H6     . DC  A 1 23 ? 12.14239 -16.97610 -3.26204  1.000 27.32914 ? 23  DC  A H6     1 
ATOM   733 P  P      . DC  A 1 24 ? 6.50111  -17.42923 -5.45130  1.000 35.45827 ? 24  DC  A P      1 
ATOM   734 O  OP1    . DC  A 1 24 ? 5.10556  -17.91070 -5.50002  1.000 31.90952 ? 24  DC  A OP1    1 
ATOM   735 O  OP2    . DC  A 1 24 ? 7.45123  -17.51564 -6.59013  1.000 30.74392 ? 24  DC  A OP2    1 
ATOM   736 O  "O5'"  . DC  A 1 24 ? 6.32166  -15.91031 -5.02171  1.000 37.01069 ? 24  DC  A "O5'"  1 
ATOM   737 C  "C5'"  . DC  A 1 24 ? 5.56073  -15.61199 -3.87340  1.000 40.13898 ? 24  DC  A "C5'"  1 
ATOM   738 C  "C4'"  . DC  A 1 24 ? 5.58890  -14.14013 -3.59212  1.000 34.72120 ? 24  DC  A "C4'"  1 
ATOM   739 O  "O4'"  . DC  A 1 24 ? 6.90122  -13.77186 -3.10801  1.000 33.16145 ? 24  DC  A "O4'"  1 
ATOM   740 C  "C3'"  . DC  A 1 24 ? 5.32985  -13.28373 -4.81816  1.000 36.84234 ? 24  DC  A "C3'"  1 
ATOM   741 O  "O3'"  . DC  A 1 24 ? 4.04304  -12.72013 -4.76024  1.000 44.48540 ? 24  DC  A "O3'"  1 
ATOM   742 C  "C2'"  . DC  A 1 24 ? 6.43564  -12.22638 -4.80167  1.000 39.94446 ? 24  DC  A "C2'"  1 
ATOM   743 C  "C1'"  . DC  A 1 24 ? 7.15409  -12.45134 -3.47118  1.000 28.75427 ? 24  DC  A "C1'"  1 
ATOM   744 N  N1     . DC  A 1 24 ? 8.63222  -12.27096 -3.53353  1.000 29.85624 ? 24  DC  A N1     1 
ATOM   745 C  C2     . DC  A 1 24 ? 9.22587  -11.27031 -2.76918  1.000 29.44443 ? 24  DC  A C2     1 
ATOM   746 O  O2     . DC  A 1 24 ? 8.50490  -10.53631 -2.07731  1.000 29.74517 ? 24  DC  A O2     1 
ATOM   747 N  N3     . DC  A 1 24 ? 10.57226 -11.12181 -2.81304  1.000 27.97709 ? 24  DC  A N3     1 
ATOM   748 C  C4     . DC  A 1 24 ? 11.30635 -11.92481 -3.58015  1.000 23.54220 ? 24  DC  A C4     1 
ATOM   749 N  N4     . DC  A 1 24 ? 12.62802 -11.73461 -3.59387  1.000 26.94865 ? 24  DC  A N4     1 
ATOM   750 C  C5     . DC  A 1 24 ? 10.71884 -12.95354 -4.37161  1.000 23.73832 ? 24  DC  A C5     1 
ATOM   751 C  C6     . DC  A 1 24 ? 9.38803  -13.08792 -4.32337  1.000 27.46022 ? 24  DC  A C6     1 
ATOM   752 H  "H5'"  . DC  A 1 24 ? 5.92576  -16.09111 -3.11307  1.000 48.22883 ? 24  DC  A "H5'"  1 
ATOM   753 H  "H5''" . DC  A 1 24 ? 4.64345  -15.89442 -4.01388  1.000 48.22883 ? 24  DC  A "H5''" 1 
ATOM   754 H  "H4'"  . DC  A 1 24 ? 4.94301  -13.91720 -2.90362  1.000 41.72750 ? 24  DC  A "H4'"  1 
ATOM   755 H  "H3'"  . DC  A 1 24 ? 5.43251  -13.82707 -5.61512  1.000 44.27287 ? 24  DC  A "H3'"  1 
ATOM   756 H  "H2'"  . DC  A 1 24 ? 7.04316  -12.35007 -5.54767  1.000 47.99541 ? 24  DC  A "H2'"  1 
ATOM   757 H  "H2''" . DC  A 1 24 ? 6.06020  -11.33303 -4.84492  1.000 47.99541 ? 24  DC  A "H2''" 1 
ATOM   758 H  "H1'"  . DC  A 1 24 ? 6.78469  -11.84491 -2.81035  1.000 34.56719 ? 24  DC  A "H1'"  1 
ATOM   759 H  H41    . DC  A 1 24 ? 12.97752 -11.10983 -3.11732  1.000 32.40044 ? 24  DC  A H41    1 
ATOM   760 H  H42    . DC  A 1 24 ? 13.12972 -12.23690 -4.07927  1.000 32.40044 ? 24  DC  A H42    1 
ATOM   761 H  H5     . DC  A 1 24 ? 11.24081 -13.51113 -4.90222  1.000 28.54805 ? 24  DC  A H5     1 
ATOM   762 H  H6     . DC  A 1 24 ? 8.97363  -13.74556 -4.83394  1.000 33.01433 ? 24  DC  A H6     1 
ATOM   763 P  P      . DG  A 1 25 ? 3.54080  -11.79569 -5.95960  1.000 44.71163 ? 25  DG  A P      1 
ATOM   764 O  OP1    . DG  A 1 25 ? 2.08032  -11.91871 -6.00384  1.000 51.82227 ? 25  DG  A OP1    1 
ATOM   765 O  OP2    . DG  A 1 25 ? 4.43575  -11.99260 -7.11779  1.000 44.92497 ? 25  DG  A OP2    1 
ATOM   766 O  "O5'"  . DG  A 1 25 ? 3.84014  -10.32351 -5.47714  1.000 36.08079 ? 25  DG  A "O5'"  1 
ATOM   767 C  "C5'"  . DG  A 1 25 ? 3.36660  -9.91557  -4.25805  1.000 37.48272 ? 25  DG  A "C5'"  1 
ATOM   768 C  "C4'"  . DG  A 1 25 ? 3.94065  -8.58275  -3.91272  1.000 39.78269 ? 25  DG  A "C4'"  1 
ATOM   769 O  "O4'"  . DG  A 1 25 ? 5.38043  -8.68269  -3.79067  1.000 37.79059 ? 25  DG  A "O4'"  1 
ATOM   770 C  "C3'"  . DG  A 1 25 ? 3.70094  -7.51245  -4.95192  1.000 49.61338 ? 25  DG  A "C3'"  1 
ATOM   771 O  "O3'"  . DG  A 1 25 ? 3.39120  -6.31319  -4.27457  1.000 53.24022 ? 25  DG  A "O3'"  1 
ATOM   772 C  "C2'"  . DG  A 1 25 ? 5.03573  -7.46666  -5.70885  1.000 36.50913 ? 25  DG  A "C2'"  1 
ATOM   773 C  "C1'"  . DG  A 1 25 ? 5.98632  -7.66325  -4.55849  1.000 39.54519 ? 25  DG  A "C1'"  1 
ATOM   774 N  N9     . DG  A 1 25 ? 7.34915  -8.09238  -4.87113  1.000 36.08368 ? 25  DG  A N9     1 
ATOM   775 C  C8     . DG  A 1 25 ? 7.73813  -9.17934  -5.62603  1.000 34.71397 ? 25  DG  A C8     1 
ATOM   776 N  N7     . DG  A 1 25 ? 9.03506  -9.35072  -5.66078  1.000 32.52107 ? 25  DG  A N7     1 
ATOM   777 C  C5     . DG  A 1 25 ? 9.53696  -8.33536  -4.84470  1.000 29.49279 ? 25  DG  A C5     1 
ATOM   778 C  C6     . DG  A 1 25 ? 10.87763 -8.01196  -4.48783  1.000 28.11348 ? 25  DG  A C6     1 
ATOM   779 O  O6     . DG  A 1 25 ? 11.92198 -8.57009  -4.82206  1.000 25.91587 ? 25  DG  A O6     1 
ATOM   780 N  N1     . DG  A 1 25 ? 10.93450 -6.91189  -3.65990  1.000 30.74541 ? 25  DG  A N1     1 
ATOM   781 C  C2     . DG  A 1 25 ? 9.85070  -6.20681  -3.21254  1.000 29.36942 ? 25  DG  A C2     1 
ATOM   782 N  N2     . DG  A 1 25 ? 10.12011 -5.18194  -2.41235  1.000 35.20394 ? 25  DG  A N2     1 
ATOM   783 N  N3     . DG  A 1 25 ? 8.59442  -6.48382  -3.53048  1.000 33.29737 ? 25  DG  A N3     1 
ATOM   784 C  C4     . DG  A 1 25 ? 8.51080  -7.56543  -4.34236  1.000 33.51114 ? 25  DG  A C4     1 
ATOM   785 H  "H5'"  . DG  A 1 25 ? 3.61824  -10.56204 -3.58008  1.000 45.04133 ? 25  DG  A "H5'"  1 
ATOM   786 H  "H5''" . DG  A 1 25 ? 2.39919  -9.85280  -4.29095  1.000 45.04133 ? 25  DG  A "H5''" 1 
ATOM   787 H  "H4'"  . DG  A 1 25 ? 3.57905  -8.29441  -3.06007  1.000 47.80129 ? 25  DG  A "H4'"  1 
ATOM   788 H  "H3'"  . DG  A 1 25 ? 2.99994  -7.74807  -5.57960  1.000 59.59812 ? 25  DG  A "H3'"  1 
ATOM   789 H  "H2'"  . DG  A 1 25 ? 5.10632  -8.17841  -6.36408  1.000 43.87302 ? 25  DG  A "H2'"  1 
ATOM   790 H  "H2''" . DG  A 1 25 ? 5.17298  -6.61476  -6.15194  1.000 43.87302 ? 25  DG  A "H2''" 1 
ATOM   791 H  "H1'"  . DG  A 1 25 ? 6.06574  -6.82111  -4.08374  1.000 47.51629 ? 25  DG  A "H1'"  1 
ATOM   792 H  H8     . DG  A 1 25 ? 7.13758  -9.73587  -6.06707  1.000 41.71882 ? 25  DG  A H8     1 
ATOM   793 H  H1     . DG  A 1 25 ? 11.71207 -6.64789  -3.40440  1.000 36.95655 ? 25  DG  A H1     1 
ATOM   794 H  H21    . DG  A 1 25 ? 9.47983  -4.69928  -2.10140  1.000 42.30679 ? 25  DG  A H21    1 
ATOM   795 H  H22    . DG  A 1 25 ? 10.93487 -5.00083  -2.20505  1.000 42.30679 ? 25  DG  A H22    1 
ATOM   796 P  P      . DC  A 1 26 ? 2.68752  -5.09789  -5.02949  1.000 66.11993 ? 26  DC  A P      1 
ATOM   797 O  OP1    . DC  A 1 26 ? 1.75082  -4.44069  -4.08618  1.000 70.50183 ? 26  DC  A OP1    1 
ATOM   798 O  OP2    . DC  A 1 26 ? 2.13701  -5.63931  -6.30760  1.000 59.45143 ? 26  DC  A OP2    1 
ATOM   799 O  "O5'"  . DC  A 1 26 ? 3.91052  -4.08374  -5.22394  1.000 58.17835 ? 26  DC  A "O5'"  1 
ATOM   800 C  "C5'"  . DC  A 1 26 ? 4.65077  -3.62553  -4.08429  1.000 47.05520 ? 26  DC  A "C5'"  1 
ATOM   801 C  "C4'"  . DC  A 1 26 ? 5.97636  -2.96882  -4.50033  1.000 55.20250 ? 26  DC  A "C4'"  1 
ATOM   802 O  "O4'"  . DC  A 1 26 ? 6.98332  -3.99692  -4.71774  1.000 55.34871 ? 26  DC  A "O4'"  1 
ATOM   803 C  "C3'"  . DC  A 1 26 ? 5.95478  -2.17374  -5.82664  1.000 56.86347 ? 26  DC  A "C3'"  1 
ATOM   804 O  "O3'"  . DC  A 1 26 ? 5.77381  -0.75159  -5.62612  1.000 60.60283 ? 26  DC  A "O3'"  1 
ATOM   805 C  "C2'"  . DC  A 1 26 ? 7.31453  -2.47884  -6.47911  1.000 47.12742 ? 26  DC  A "C2'"  1 
ATOM   806 C  "C1'"  . DC  A 1 26 ? 8.00048  -3.43524  -5.51705  1.000 43.09561 ? 26  DC  A "C1'"  1 
ATOM   807 N  N1     . DC  A 1 26 ? 8.72498  -4.49191  -6.22180  1.000 33.16155 ? 26  DC  A N1     1 
ATOM   808 C  C2     . DC  A 1 26 ? 10.09625 -4.56872  -6.10331  1.000 31.34662 ? 26  DC  A C2     1 
ATOM   809 O  O2     . DC  A 1 26 ? 10.67946 -3.77064  -5.36929  1.000 36.22919 ? 26  DC  A O2     1 
ATOM   810 N  N3     . DC  A 1 26 ? 10.74737 -5.52078  -6.78140  1.000 31.37952 ? 26  DC  A N3     1 
ATOM   811 C  C4     . DC  A 1 26 ? 10.07002 -6.35932  -7.55883  1.000 30.64704 ? 26  DC  A C4     1 
ATOM   812 N  N4     . DC  A 1 26 ? 10.74369 -7.27898  -8.20936  1.000 29.81199 ? 26  DC  A N4     1 
ATOM   813 C  C5     . DC  A 1 26 ? 8.67434  -6.28337  -7.70579  1.000 35.06915 ? 26  DC  A C5     1 
ATOM   814 C  C6     . DC  A 1 26 ? 8.05020  -5.33608  -7.03265  1.000 34.11231 ? 26  DC  A C6     1 
ATOM   815 H  "H5'"  . DC  A 1 26 ? 4.83904  -4.37994  -3.50437  1.000 56.52830 ? 26  DC  A "H5'"  1 
ATOM   816 H  "H5''" . DC  A 1 26 ? 4.11571  -2.97904  -3.59780  1.000 56.52830 ? 26  DC  A "H5''" 1 
ATOM   817 H  "H4'"  . DC  A 1 26 ? 6.25118  -2.37818  -3.78163  1.000 66.30506 ? 26  DC  A "H4'"  1 
ATOM   818 H  "H3'"  . DC  A 1 26 ? 5.22989  -2.52703  -6.36572  1.000 68.29823 ? 26  DC  A "H3'"  1 
ATOM   819 H  "H2'"  . DC  A 1 26 ? 7.19372  -2.89302  -7.34788  1.000 56.61497 ? 26  DC  A "H2'"  1 
ATOM   820 H  "H2''" . DC  A 1 26 ? 7.83447  -1.66695  -6.58587  1.000 56.61497 ? 26  DC  A "H2''" 1 
ATOM   821 H  "H1'"  . DC  A 1 26 ? 8.60948  -2.96098  -4.92959  1.000 51.77679 ? 26  DC  A "H1'"  1 
ATOM   822 H  H41    . DC  A 1 26 ? 10.33048 -7.83459  -8.71941  1.000 35.83645 ? 26  DC  A H41    1 
ATOM   823 H  H42    . DC  A 1 26 ? 11.59831 -7.32593  -8.12555  1.000 35.83645 ? 26  DC  A H42    1 
ATOM   824 H  H5     . DC  A 1 26 ? 8.21109  -6.87509  -8.25367  1.000 42.14504 ? 26  DC  A H5     1 
ATOM   825 H  H6     . DC  A 1 26 ? 7.12834  -5.24762  -7.11781  1.000 40.99683 ? 26  DC  A H6     1 
ATOM   826 P  P      . DC  A 1 27 ? 6.03374  0.26439   -6.85788  1.000 69.31024 ? 27  DC  A P      1 
ATOM   827 O  OP1    . DC  A 1 27 ? 5.09535  1.39212   -6.68059  1.000 67.88867 ? 27  DC  A OP1    1 
ATOM   828 O  OP2    . DC  A 1 27 ? 6.06310  -0.44946  -8.17039  1.000 47.39130 ? 27  DC  A OP2    1 
ATOM   829 O  "O5'"  . DC  A 1 27 ? 7.51264  0.80970   -6.57586  1.000 59.38660 ? 27  DC  A "O5'"  1 
ATOM   830 C  "C5'"  . DC  A 1 27 ? 8.12640  0.65907   -5.27808  1.000 46.26974 ? 27  DC  A "C5'"  1 
ATOM   831 C  "C4'"  . DC  A 1 27 ? 9.59217  0.98807   -5.37664  1.000 46.13926 ? 27  DC  A "C4'"  1 
ATOM   832 O  "O4'"  . DC  A 1 27 ? 10.32570 -0.16923  -5.85774  1.000 41.37230 ? 27  DC  A "O4'"  1 
ATOM   833 C  "C3'"  . DC  A 1 27 ? 9.89985  2.12415   -6.34909  1.000 47.06951 ? 27  DC  A "C3'"  1 
ATOM   834 O  "O3'"  . DC  A 1 27 ? 10.82524 3.00914   -5.78010  1.000 55.27409 ? 27  DC  A "O3'"  1 
ATOM   835 C  "C2'"  . DC  A 1 27 ? 10.44699 1.42196   -7.59360  1.000 43.68098 ? 27  DC  A "C2'"  1 
ATOM   836 C  "C1'"  . DC  A 1 27 ? 11.06432 0.15603   -7.02884  1.000 37.43989 ? 27  DC  A "C1'"  1 
ATOM   837 N  N1     . DC  A 1 27 ? 11.00960 -1.02647  -7.94615  1.000 32.74623 ? 27  DC  A N1     1 
ATOM   838 C  C2     . DC  A 1 27 ? 12.18803 -1.68525  -8.31324  1.000 29.97395 ? 27  DC  A C2     1 
ATOM   839 O  O2     . DC  A 1 27 ? 13.27405 -1.25538  -7.89784  1.000 27.63640 ? 27  DC  A O2     1 
ATOM   840 N  N3     . DC  A 1 27 ? 12.10791 -2.78363  -9.12561  1.000 30.22714 ? 27  DC  A N3     1 
ATOM   841 C  C4     . DC  A 1 27 ? 10.91504 -3.21229  -9.53792  1.000 28.96614 ? 27  DC  A C4     1 
ATOM   842 N  N4     . DC  A 1 27 ? 10.86824 -4.28934  -10.32854 1.000 28.54016 ? 27  DC  A N4     1 
ATOM   843 C  C5     . DC  A 1 27 ? 9.71241  -2.55282  -9.16423  1.000 31.93033 ? 27  DC  A C5     1 
ATOM   844 C  C6     . DC  A 1 27 ? 9.80468  -1.47806  -8.37714  1.000 36.38690 ? 27  DC  A C6     1 
ATOM   845 H  "H5'"  . DC  A 1 27 ? 8.01785  -0.25455  -4.97079  1.000 55.58575 ? 27  DC  A "H5'"  1 
ATOM   846 H  "H5''" . DC  A 1 27 ? 7.70028  1.25789   -4.64505  1.000 55.58575 ? 27  DC  A "H5''" 1 
ATOM   847 H  "H4'"  . DC  A 1 27 ? 9.93934  1.21109   -4.49878  1.000 55.42917 ? 27  DC  A "H4'"  1 
ATOM   848 H  "H3'"  . DC  A 1 27 ? 9.08036  2.58688   -6.58408  1.000 56.54548 ? 27  DC  A "H3'"  1 
ATOM   849 H  "H2'"  . DC  A 1 27 ? 9.73624  1.21576   -8.22066  1.000 52.47924 ? 27  DC  A "H2'"  1 
ATOM   850 H  "H2''" . DC  A 1 27 ? 11.11317 1.96794   -8.03971  1.000 52.47924 ? 27  DC  A "H2''" 1 
ATOM   851 H  "H1'"  . DC  A 1 27 ? 11.98865 0.34152   -6.80055  1.000 44.98992 ? 27  DC  A "H1'"  1 
ATOM   852 H  H41    . DC  A 1 27 ? 10.11054 -4.58525  -10.60770 1.000 34.31025 ? 27  DC  A H41    1 
ATOM   853 H  H42    . DC  A 1 27 ? 11.59584 -4.68628  -10.55798 1.000 34.31025 ? 27  DC  A H42    1 
ATOM   854 H  H5     . DC  A 1 27 ? 8.88592  -2.86076  -9.45917  1.000 38.37845 ? 27  DC  A H5     1 
ATOM   855 H  H6     . DC  A 1 27 ? 9.03038  -1.03164  -8.12009  1.000 43.72634 ? 27  DC  A H6     1 
ATOM   856 P  P      . DG  A 1 28 ? 10.93486 4.51617   -6.30541  1.000 56.23351 ? 28  DG  A P      1 
ATOM   857 O  OP1    . DG  A 1 28 ? 11.42802 5.30007   -5.15674  1.000 63.13501 ? 28  DG  A OP1    1 
ATOM   858 O  OP2    . DG  A 1 28 ? 9.72223  4.93032   -7.05171  1.000 56.14111 ? 28  DG  A OP2    1 
ATOM   859 O  "O5'"  . DG  A 1 28 ? 12.11285 4.43962   -7.34499  1.000 46.06207 ? 28  DG  A "O5'"  1 
ATOM   860 C  "C5'"  . DG  A 1 28 ? 13.34115 3.95764   -6.92113  1.000 44.85664 ? 28  DG  A "C5'"  1 
ATOM   861 C  "C4'"  . DG  A 1 28 ? 14.24204 3.78756   -8.09619  1.000 37.26602 ? 28  DG  A "C4'"  1 
ATOM   862 O  "O4'"  . DG  A 1 28 ? 13.93744 2.52509   -8.74936  1.000 40.78472 ? 28  DG  A "O4'"  1 
ATOM   863 C  "C3'"  . DG  A 1 28 ? 14.08174 4.86555   -9.15473  1.000 45.07751 ? 28  DG  A "C3'"  1 
ATOM   864 O  "O3'"  . DG  A 1 28 ? 15.35461 5.29327   -9.60962  1.000 45.19555 ? 28  DG  A "O3'"  1 
ATOM   865 C  "C2'"  . DG  A 1 28 ? 13.26309 4.16221   -10.23102 1.000 41.74031 ? 28  DG  A "C2'"  1 
ATOM   866 C  "C1'"  . DG  A 1 28 ? 13.78012 2.74688   -10.12190 1.000 38.38995 ? 28  DG  A "C1'"  1 
ATOM   867 N  N9     . DG  A 1 28 ? 12.90461 1.71277   -10.69511 1.000 33.72616 ? 28  DG  A N9     1 
ATOM   868 C  C8     . DG  A 1 28 ? 11.52973 1.73288   -10.81987 1.000 38.16130 ? 28  DG  A C8     1 
ATOM   869 N  N7     . DG  A 1 28 ? 11.04194 0.65151   -11.38613 1.000 34.90875 ? 28  DG  A N7     1 
ATOM   870 C  C5     . DG  A 1 28 ? 12.17258 -0.11905  -11.66355 1.000 32.10071 ? 28  DG  A C5     1 
ATOM   871 C  C6     . DG  A 1 28 ? 12.29385 -1.38651  -12.27817 1.000 32.84603 ? 28  DG  A C6     1 
ATOM   872 O  O6     . DG  A 1 28 ? 11.39922 -2.11402  -12.72335 1.000 34.63495 ? 28  DG  A O6     1 
ATOM   873 N  N1     . DG  A 1 28 ? 13.60930 -1.79653  -12.35572 1.000 30.55174 ? 28  DG  A N1     1 
ATOM   874 C  C2     . DG  A 1 28 ? 14.68320 -1.07339  -11.90051 1.000 32.40367 ? 28  DG  A C2     1 
ATOM   875 N  N2     . DG  A 1 28 ? 15.88528 -1.63152  -12.07180 1.000 33.12316 ? 28  DG  A N2     1 
ATOM   876 N  N3     . DG  A 1 28 ? 14.59102 0.10919   -11.33509 1.000 31.31985 ? 28  DG  A N3     1 
ATOM   877 C  C4     . DG  A 1 28 ? 13.31637 0.52247   -11.23822 1.000 33.67835 ? 28  DG  A C4     1 
ATOM   878 H  "H5'"  . DG  A 1 28 ? 13.21974 3.10319   -6.47834  1.000 53.89003 ? 28  DG  A "H5'"  1 
ATOM   879 H  "H5''" . DG  A 1 28 ? 13.73771 4.58398   -6.29555  1.000 53.89003 ? 28  DG  A "H5''" 1 
ATOM   880 H  "H4'"  . DG  A 1 28 ? 15.16770 3.76389   -7.80721  1.000 44.78129 ? 28  DG  A "H4'"  1 
ATOM   881 H  "H3'"  . DG  A 1 28 ? 13.58177 5.62253   -8.81134  1.000 54.15508 ? 28  DG  A "H3'"  1 
ATOM   882 H  "H2'"  . DG  A 1 28 ? 12.31239 4.21016   -10.04454 1.000 50.15044 ? 28  DG  A "H2'"  1 
ATOM   883 H  "H2''" . DG  A 1 28 ? 13.43186 4.53700   -11.10962 1.000 50.15044 ? 28  DG  A "H2''" 1 
ATOM   884 H  "H1'"  . DG  A 1 28 ? 14.63600 2.67571   -10.57279 1.000 46.13000 ? 28  DG  A "H1'"  1 
ATOM   885 H  H8     . DG  A 1 28 ? 11.00092 2.44155   -10.53172 1.000 45.85562 ? 28  DG  A H8     1 
ATOM   886 H  H1     . DG  A 1 28 ? 13.76771 -2.56132  -12.71573 1.000 36.72415 ? 28  DG  A H1     1 
ATOM   887 H  H21    . DG  A 1 28 ? 16.59275 -1.21694  -11.81256 1.000 39.80985 ? 28  DG  A H21    1 
ATOM   888 H  H22    . DG  A 1 28 ? 15.95140 -2.40529  -12.44128 1.000 39.80985 ? 28  DG  A H22    1 
ATOM   889 P  P      . DC  A 1 29 ? 15.50762 6.65625   -10.43191 1.000 47.34952 ? 29  DC  A P      1 
ATOM   890 O  OP1    . DC  A 1 29 ? 15.71165 7.78061   -9.49138  1.000 50.73829 ? 29  DC  A OP1    1 
ATOM   891 O  OP2    . DC  A 1 29 ? 14.40648 6.68280   -11.41846 1.000 55.64583 ? 29  DC  A OP2    1 
ATOM   892 O  "O5'"  . DC  A 1 29 ? 16.83932 6.46606   -11.27750 1.000 51.98866 ? 29  DC  A "O5'"  1 
ATOM   893 C  "C5'"  . DC  A 1 29 ? 17.65711 5.30338   -11.10873 1.000 48.49039 ? 29  DC  A "C5'"  1 
ATOM   894 C  "C4'"  . DC  A 1 29 ? 17.68449 4.45216   -12.38106 1.000 48.74044 ? 29  DC  A "C4'"  1 
ATOM   895 O  "O4'"  . DC  A 1 29 ? 16.55646 3.56019   -12.40258 1.000 44.29926 ? 29  DC  A "O4'"  1 
ATOM   896 C  "C3'"  . DC  A 1 29 ? 17.55176 5.19765   -13.68719 1.000 39.82717 ? 29  DC  A "C3'"  1 
ATOM   897 O  "O3'"  . DC  A 1 29 ? 18.81872 5.69488   -14.13313 1.000 39.37466 ? 29  DC  A "O3'"  1 
ATOM   898 C  "C2'"  . DC  A 1 29 ? 16.95627 4.12381   -14.62733 1.000 39.36225 ? 29  DC  A "C2'"  1 
ATOM   899 C  "C1'"  . DC  A 1 29 ? 16.49034 3.01285   -13.68564 1.000 37.84014 ? 29  DC  A "C1'"  1 
ATOM   900 N  N1     . DC  A 1 29 ? 15.08742 2.52169   -13.94627 1.000 37.15035 ? 29  DC  A N1     1 
ATOM   901 C  C2     . DC  A 1 29 ? 14.88653 1.24335   -14.48340 1.000 37.07289 ? 29  DC  A C2     1 
ATOM   902 O  O2     . DC  A 1 29 ? 15.86119 0.53434   -14.72893 1.000 43.23963 ? 29  DC  A O2     1 
ATOM   903 N  N3     . DC  A 1 29 ? 13.63333 0.81867   -14.72533 1.000 36.61860 ? 29  DC  A N3     1 
ATOM   904 C  C4     . DC  A 1 29 ? 12.59816 1.59972   -14.44187 1.000 36.38577 ? 29  DC  A C4     1 
ATOM   905 N  N4     . DC  A 1 29 ? 11.36370 1.13001   -14.70606 1.000 37.77306 ? 29  DC  A N4     1 
ATOM   906 C  C5     . DC  A 1 29 ? 12.77384 2.89941   -13.88661 1.000 38.08000 ? 29  DC  A C5     1 
ATOM   907 C  C6     . DC  A 1 29 ? 14.02827 3.31900   -13.66142 1.000 37.12506 ? 29  DC  A C6     1 
ATOM   908 H  "H5'"  . DC  A 1 29 ? 17.30567 4.77114   -10.37791 1.000 58.25053 ? 29  DC  A "H5'"  1 
ATOM   909 H  "H5''" . DC  A 1 29 ? 18.56128 5.57970   -10.89184 1.000 58.25053 ? 29  DC  A "H5''" 1 
ATOM   910 H  "H4'"  . DC  A 1 29 ? 18.51658 3.95378   -12.36919 1.000 58.55059 ? 29  DC  A "H4'"  1 
ATOM   911 H  "H3'"  . DC  A 1 29 ? 16.93335 5.93899   -13.59292 1.000 47.85467 ? 29  DC  A "H3'"  1 
ATOM   912 H  "HO3'" . DC  A 1 29 ? 19.15604 5.40578   -14.84604 1.000 46.93928 ? 29  DC  A "HO3'" 1 
ATOM   913 H  "H2'"  . DC  A 1 29 ? 16.21085 4.48284   -15.13363 1.000 47.29676 ? 29  DC  A "H2'"  1 
ATOM   914 H  "H2''" . DC  A 1 29 ? 17.62790 3.79432   -15.24478 1.000 47.29676 ? 29  DC  A "H2''" 1 
ATOM   915 H  "H1'"  . DC  A 1 29 ? 17.09096 2.25399   -13.75107 1.000 45.47023 ? 29  DC  A "H1'"  1 
ATOM   916 H  H41    . DC  A 1 29 ? 10.67363 1.61326   -14.53318 1.000 45.01737 ? 29  DC  A H41    1 
ATOM   917 H  H42    . DC  A 1 29 ? 11.26559 0.34687   -15.04762 1.000 45.01737 ? 29  DC  A H42    1 
ATOM   918 H  H5     . DC  A 1 29 ? 12.04343 3.43929   -13.68676 1.000 45.38569 ? 29  DC  A H5     1 
ATOM   919 H  H6     . DC  A 1 29 ? 14.17292 4.16614   -13.30601 1.000 44.23976 ? 29  DC  A H6     1 
HETATM 920 C  C11    . I7U B 2 .  ? 13.63985 -14.16502 3.29440   1.000 23.89511 ? 101 I7U A C11    1 
HETATM 921 C  C01    . I7U B 2 .  ? 9.79385  -16.04473 2.03843   1.000 22.54845 ? 101 I7U A C01    1 
HETATM 922 C  C03    . I7U B 2 .  ? 11.34577 -14.43304 3.21056   1.000 20.65070 ? 101 I7U A C03    1 
HETATM 923 C  C04    . I7U B 2 .  ? 11.60186 -13.39615 4.02156   1.000 23.67807 ? 101 I7U A C04    1 
HETATM 924 C  C05    . I7U B 2 .  ? 10.52398 -12.60040 4.73465   1.000 21.50635 ? 101 I7U A C05    1 
HETATM 925 C  C08    . I7U B 2 .  ? 8.98350  -14.15604 3.57562   1.000 20.46400 ? 101 I7U A C08    1 
HETATM 926 N  N02    . I7U B 2 .  ? 10.00520 -14.91551 2.92770   1.000 20.21084 ? 101 I7U A N02    1 
HETATM 927 N  N07    . I7U B 2 .  ? 9.22848  -13.06885 4.42658   1.000 20.14892 ? 101 I7U A N07    1 
HETATM 928 N  N10    . I7U B 2 .  ? 12.89008 -13.33010 4.00085   1.000 23.10340 ? 101 I7U A N10    1 
HETATM 929 N  N12    . I7U B 2 .  ? 12.76014 -14.95547 2.72433   1.000 22.40283 ? 101 I7U A N12    1 
HETATM 930 O  O06    . I7U B 2 .  ? 10.76755 -11.52903 5.58518   1.000 23.69776 ? 101 I7U A O06    1 
HETATM 931 O  O09    . I7U B 2 .  ? 7.66619  -14.52712 3.35208   1.000 22.20658 ? 101 I7U A O09    1 
HETATM 932 H  H111   . I7U B 2 .  ? 14.69287 -14.37045 3.44213   1.000 28.73619 ? 101 I7U A H111   1 
HETATM 933 H  H013   . I7U B 2 .  ? 10.54438 -16.03481 1.25773   1.000 27.12021 ? 101 I7U A H013   1 
HETATM 934 H  H012   . I7U B 2 .  ? 8.80903  -15.97434 1.59338   1.000 27.12021 ? 101 I7U A H012   1 
HETATM 935 H  H011   . I7U B 2 .  ? 9.87059  -16.96677 2.60131   1.000 27.12021 ? 101 I7U A H011   1 
HETATM 936 H  H071   . I7U B 2 .  ? 8.44440  -12.60085 4.83670   1.000 24.24077 ? 101 I7U A H071   1 
HETATM 937 H  H101   . I7U B 2 .  ? 13.32117 -12.93563 4.81360   1.000 27.78614 ? 101 I7U A H101   1 
HETATM 938 NA NA     . NA  C 3 .  ? 13.56754 -10.28030 -9.09037  1.000 36.50108 ? 102 NA  A NA     1 
HETATM 939 NA NA     . NA  D 3 .  ? 18.52326 0.05621   -10.29376 1.000 33.77256 ? 103 NA  A NA     1 
HETATM 940 NA NA     . NA  E 3 .  ? 19.75497 -18.28961 -4.49229  1.000 11.89927 ? 104 NA  A NA     1 
HETATM 941 NA NA     . NA  F 3 .  ? 19.81076 -14.30158 3.35582   1.000 20.75073 ? 105 NA  A NA     1 
HETATM 942 O  O      . HOH G 4 .  ? 5.63054  0.74083   -4.07962  1.000 48.48902 ? 201 HOH A O      1 
HETATM 943 O  O      . HOH G 4 .  ? 28.34022 -14.88940 3.30325   1.000 25.54809 ? 202 HOH A O      1 
HETATM 944 O  O      . HOH G 4 .  ? 25.55061 -13.84152 3.67508   1.000 40.42563 ? 203 HOH A O      1 
HETATM 945 O  O      . HOH G 4 .  ? 15.48187 -25.22648 8.25087   1.000 49.11552 ? 204 HOH A O      1 
HETATM 946 O  O      . HOH G 4 .  ? 27.35695 -11.06784 4.10804   1.000 34.70496 ? 205 HOH A O      1 
HETATM 947 O  O      . HOH G 4 .  ? 13.74628 -18.61387 22.81296  1.000 22.58292 ? 206 HOH A O      1 
HETATM 948 O  O      . HOH G 4 .  ? 21.37056 -15.54693 1.76015   1.000 30.07511 ? 207 HOH A O      1 
HETATM 949 O  O      . HOH G 4 .  ? 6.22138  -10.77575 -8.49337  0.50  39.09607 ? 208 HOH A O      1 
HETATM 950 O  O      . HOH G 4 .  ? 19.19628 -5.20797  2.09256   1.000 33.43239 ? 209 HOH A O      1 
HETATM 951 O  O      . HOH G 4 .  ? 3.580    -18.127   -7.594    1.000 46.46448 ? 210 HOH A O      1 
HETATM 952 O  O      . HOH G 4 .  ? 17.37214 -12.87601 9.35609   1.000 22.51687 ? 211 HOH A O      1 
HETATM 953 O  O      . HOH G 4 .  ? 7.25665  -11.43202 5.04502   1.000 31.50775 ? 212 HOH A O      1 
HETATM 954 O  O      . HOH G 4 .  ? 9.66153  -17.33345 10.56681  1.000 29.31347 ? 213 HOH A O      1 
HETATM 955 O  O      . HOH G 4 .  ? 21.90291 -5.88887  0.88100   1.000 30.99863 ? 214 HOH A O      1 
HETATM 956 O  O      . HOH G 4 .  ? 22.18965 -5.92999  6.83346   1.000 31.51498 ? 215 HOH A O      1 
HETATM 957 O  O      . HOH G 4 .  ? 24.10063 -9.72525  11.16120  1.000 20.86603 ? 216 HOH A O      1 
HETATM 958 O  O      . HOH G 4 .  ? 7.50221  -10.19853 2.68017   1.000 33.45855 ? 217 HOH A O      1 
HETATM 959 O  O      . HOH G 4 .  ? 17.01000 -12.02189 -14.63101 1.000 38.59621 ? 218 HOH A O      1 
HETATM 960 O  O      . HOH G 4 .  ? 23.266   -6.848    10.454    1.000 24.94785 ? 219 HOH A O      1 
HETATM 961 O  O      . HOH G 4 .  ? 20.56045 -8.60854  -7.38510  1.000 34.67122 ? 220 HOH A O      1 
HETATM 962 O  O      . HOH G 4 .  ? 17.87411 -13.95446 1.53034   1.000 23.27370 ? 221 HOH A O      1 
HETATM 963 O  O      . HOH G 4 .  ? 20.18901 -12.36529 2.00205   1.000 24.36325 ? 222 HOH A O      1 
HETATM 964 O  O      . HOH G 4 .  ? 14.95808 -12.49986 -21.17985 1.000 34.30358 ? 223 HOH A O      1 
HETATM 965 O  O      . HOH G 4 .  ? 16.99401 -7.04295  10.99680  1.000 24.58466 ? 224 HOH A O      1 
HETATM 966 O  O      . HOH G 4 .  ? 7.55948  -8.21445  1.35617   1.000 32.17701 ? 225 HOH A O      1 
HETATM 967 O  O      . HOH G 4 .  ? 14.32052 -13.38423 -5.16398  1.000 27.77208 ? 226 HOH A O      1 
HETATM 968 O  O      . HOH G 4 .  ? 20.338   -17.419   20.097    1.000 38.55241 ? 227 HOH A O      1 
HETATM 969 O  O      . HOH G 4 .  ? 19.16616 -13.86763 -0.81772  1.000 28.32520 ? 228 HOH A O      1 
HETATM 970 O  O      . HOH G 4 .  ? 15.91308 -19.25672 22.22041  1.000 34.26106 ? 229 HOH A O      1 
HETATM 971 O  O      . HOH G 4 .  ? 6.93010  -15.02199 -0.41814  1.000 34.90325 ? 230 HOH A O      1 
HETATM 972 O  O      . HOH G 4 .  ? 19.45071 -12.64694 5.32386   1.000 29.93344 ? 231 HOH A O      1 
HETATM 973 O  O      . HOH G 4 .  ? 19.71340 -14.85815 -3.45536  1.000 37.79881 ? 232 HOH A O      1 
HETATM 974 O  O      . HOH G 4 .  ? 10.948   -22.855   12.822    1.000 38.01687 ? 233 HOH A O      1 
HETATM 975 O  O      . HOH G 4 .  ? 4.30062  -6.07374  8.65092   1.000 48.30544 ? 234 HOH A O      1 
HETATM 976 O  O      . HOH G 4 .  ? 12.74314 -7.23249  7.48087   1.000 29.76123 ? 235 HOH A O      1 
HETATM 977 O  O      . HOH G 4 .  ? 18.52917 -16.71257 8.34615   1.000 24.21228 ? 236 HOH A O      1 
HETATM 978 O  O      . HOH G 4 .  ? 13.29030 -9.69823  -14.40987 1.000 40.83206 ? 237 HOH A O      1 
HETATM 979 O  O      . HOH G 4 .  ? 12.78097 -8.72987  -11.15544 1.000 37.95965 ? 238 HOH A O      1 
HETATM 980 O  O      . HOH G 4 .  ? 16.77553 -13.56613 -2.69946  1.000 28.22028 ? 239 HOH A O      1 
HETATM 981 O  O      . HOH G 4 .  ? 18.35772 0.04266   -12.83164 1.000 47.06074 ? 240 HOH A O      1 
HETATM 982 O  O      . HOH G 4 .  ? 15.71909 -10.26156 -8.76162  1.000 38.35603 ? 241 HOH A O      1 
HETATM 983 O  O      . HOH G 4 .  ? 14.26407 -22.18061 1.84652   1.000 37.41445 ? 242 HOH A O      1 
HETATM 984 O  O      . HOH G 4 .  ? 15.038   10.249    -11.390   1.000 46.54887 ? 243 HOH A O      1 
HETATM 985 O  O      . HOH G 4 .  ? 11.885   -24.971   10.681    1.000 37.97190 ? 244 HOH A O      1 
HETATM 986 O  O      . HOH G 4 .  ? 18.01442 -16.54313 -4.77365  1.000 31.00616 ? 245 HOH A O      1 
HETATM 987 O  O      . HOH G 4 .  ? 10.92849 -7.14582  9.43315   1.000 32.52016 ? 246 HOH A O      1 
HETATM 988 O  O      . HOH G 4 .  ? 15.28508 -27.27836 5.95494   1.000 39.62685 ? 247 HOH A O      1 
HETATM 989 O  O      . HOH G 4 .  ? 19.15256 -14.59277 5.36897   1.000 26.04773 ? 248 HOH A O      1 
HETATM 990 O  O      . HOH G 4 .  ? 19.77497 -20.32900 5.03412   1.000 33.70856 ? 249 HOH A O      1 
HETATM 991 O  O      . HOH G 4 .  ? 19.23372 -18.04631 6.41950   1.000 28.51602 ? 250 HOH A O      1 
HETATM 992 O  O      . HOH G 4 .  ? 6.52066  -0.80207  -11.74174 1.000 38.85193 ? 251 HOH A O      1 
HETATM 993 O  O      . HOH G 4 .  ? 16.22981 -23.29387 2.73238   1.000 31.35764 ? 252 HOH A O      1 
HETATM 994 O  O      . HOH G 4 .  ? 7.15501  -1.27564  -13.85790 1.000 41.96939 ? 253 HOH A O      1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1   O "O5'" . DG A 1  ? 0.97886 0.73716 0.56305 -0.16684 -0.06215 0.06908  1  DG A "O5'" 
2   C "C5'" . DG A 1  ? 0.84797 0.62112 0.49410 -0.17525 -0.06447 0.06950  1  DG A "C5'" 
3   C "C4'" . DG A 1  ? 0.74952 0.50355 0.40446 -0.16101 -0.02588 0.04965  1  DG A "C4'" 
4   O "O4'" . DG A 1  ? 0.80009 0.57664 0.44809 -0.13858 0.00008  0.05929  1  DG A "O4'" 
5   C "C3'" . DG A 1  ? 0.65926 0.44081 0.38155 -0.16338 -0.02589 0.05741  1  DG A "C3'" 
6   O "O3'" . DG A 1  ? 0.82279 0.56994 0.54515 -0.15872 0.00087  0.03070  1  DG A "O3'" 
7   C "C2'" . DG A 1  ? 0.69249 0.53487 0.44615 -0.14632 -0.01834 0.08556  1  DG A "C2'" 
8   C "C1'" . DG A 1  ? 0.69994 0.52149 0.40325 -0.13005 0.00906  0.07297  1  DG A "C1'" 
9   N N9    . DG A 1  ? 0.61580 0.47995 0.32451 -0.11322 0.01512  0.09933  1  DG A N9    
10  C C8    . DG A 1  ? 0.59373 0.49931 0.31762 -0.11216 -0.00766 0.13293  1  DG A C8    
11  N N7    . DG A 1  ? 0.57602 0.51049 0.30244 -0.09136 0.01013  0.15169  1  DG A N7    
12  C C5    . DG A 1  ? 0.56760 0.47527 0.27701 -0.08135 0.04494  0.12580  1  DG A C5    
13  C C6    . DG A 1  ? 0.61095 0.52411 0.31237 -0.06148 0.07709  0.12603  1  DG A C6    
14  O O6    . DG A 1  ? 0.58943 0.53039 0.29560 -0.04451 0.08498  0.15074  1  DG A O6    
15  N N1    . DG A 1  ? 0.64909 0.52984 0.33787 -0.06282 0.10313  0.09294  1  DG A N1    
16  C C2    . DG A 1  ? 0.65064 0.50198 0.33834 -0.07730 0.10115  0.06687  1  DG A C2    
17  N N2    . DG A 1  ? 0.66035 0.49184 0.34465 -0.07658 0.12826  0.04009  1  DG A N2    
18  N N3    . DG A 1  ? 0.62506 0.46702 0.31793 -0.09200 0.07549  0.06678  1  DG A N3    
19  C C4    . DG A 1  ? 0.57672 0.44575 0.27830 -0.09480 0.04737  0.09516  1  DG A C4    
32  P P     . DC A 2  ? 0.87791 0.61881 0.65121 -0.16666 -0.00178 0.02734  2  DC A P     
33  O OP1   . DC A 2  ? 0.75753 0.42845 0.49718 -0.17790 0.00172  -0.00296 2  DC A OP1   
34  O OP2   . DC A 2  ? 0.71849 0.51192 0.54819 -0.17273 -0.02633 0.06139  2  DC A OP2   
35  O "O5'" . DC A 2  ? 0.76407 0.52080 0.55947 -0.14900 0.02998  0.01933  2  DC A "O5'" 
36  C "C5'" . DC A 2  ? 0.68451 0.41522 0.44001 -0.13947 0.05811  -0.00330 2  DC A "C5'" 
37  C "C4'" . DC A 2  ? 0.64775 0.42376 0.42524 -0.12594 0.07509  0.00319  2  DC A "C4'" 
38  O "O4'" . DC A 2  ? 0.63702 0.44042 0.39749 -0.12046 0.06867  0.02145  2  DC A "O4'" 
39  C "C3'" . DC A 2  ? 0.60300 0.42980 0.44123 -0.12276 0.06819  0.02010  2  DC A "C3'" 
40  O "O3'" . DC A 2  ? 0.56466 0.38136 0.42740 -0.12030 0.08414  0.00444  2  DC A "O3'" 
41  C "C2'" . DC A 2  ? 0.60555 0.47927 0.44567 -0.11222 0.07491  0.03132  2  DC A "C2'" 
42  C "C1'" . DC A 2  ? 0.61788 0.46947 0.40807 -0.11032 0.07788  0.03106  2  DC A "C1'" 
43  N N1    . DC A 2  ? 0.58331 0.47607 0.38099 -0.10542 0.06212  0.06161  2  DC A N1    
44  C C2    . DC A 2  ? 0.51368 0.43242 0.30405 -0.09181 0.07813  0.06781  2  DC A C2    
45  O O2    . DC A 2  ? 0.54327 0.45042 0.32194 -0.08747 0.10270  0.04573  2  DC A O2    
46  N N3    . DC A 2  ? 0.54865 0.50416 0.34761 -0.08422 0.06768  0.09791  2  DC A N3    
47  C C4    . DC A 2  ? 0.53103 0.50261 0.35004 -0.09231 0.04005  0.12212  2  DC A C4    
48  N N4    . DC A 2  ? 0.47012 0.48363 0.30452 -0.08373 0.03226  0.15461  2  DC A N4    
49  C C5    . DC A 2  ? 0.58336 0.52738 0.40985 -0.11026 0.02068  0.11371  2  DC A C5    
50  C C6    . DC A 2  ? 0.51251 0.41531 0.32548 -0.11483 0.03388  0.08298  2  DC A C6    
62  P P     . DG A 3  ? 0.52939 0.39590 0.45570 -0.11557 0.07612  0.02388  3  DG A P     
63  O OP1   . DG A 3  ? 0.56032 0.40043 0.51125 -0.11401 0.08881  0.01095  3  DG A OP1   
64  O OP2   . DG A 3  ? 0.48217 0.37620 0.42868 -0.11966 0.05036  0.05456  3  DG A OP2   
65  O "O5'" . DG A 3  ? 0.47658 0.39406 0.40988 -0.10667 0.08653  0.02386  3  DG A "O5'" 
66  C "C5'" . DG A 3  ? 0.47967 0.37995 0.38963 -0.10557 0.11030  -0.00246 3  DG A "C5'" 
67  C "C4'" . DG A 3  ? 0.51922 0.46579 0.43066 -0.10121 0.11490  -0.00178 3  DG A "C4'" 
68  O "O4'" . DG A 3  ? 0.44505 0.40006 0.32933 -0.09806 0.10687  0.01393  3  DG A "O4'" 
69  C "C3'" . DG A 3  ? 0.41044 0.41905 0.36773 -0.09686 0.10334  0.01311  3  DG A "C3'" 
70  O "O3'" . DG A 3  ? 0.41502 0.44855 0.37252 -0.09784 0.11556  -0.00500 3  DG A "O3'" 
71  C "C2'" . DG A 3  ? 0.41944 0.46012 0.37614 -0.09215 0.08473  0.04328  3  DG A "C2'" 
72  C "C1'" . DG A 3  ? 0.41133 0.42433 0.32073 -0.09213 0.09349  0.03666  3  DG A "C1'" 
73  N N9    . DG A 3  ? 0.41071 0.43092 0.31587 -0.09002 0.07754  0.06438  3  DG A N9    
74  C C8    . DG A 3  ? 0.41736 0.42531 0.33941 -0.09654 0.05895  0.08133  3  DG A C8    
75  N N7    . DG A 3  ? 0.41660 0.43959 0.33619 -0.09563 0.04628  0.10573  3  DG A N7    
76  C C5    . DG A 3  ? 0.40903 0.45431 0.30721 -0.08413 0.06024  0.10631  3  DG A C5    
77  C C6    . DG A 3  ? 0.40708 0.47721 0.29714 -0.07483 0.05917  0.13028  3  DG A C6    
78  O O6    . DG A 3  ? 0.43388 0.51890 0.33948 -0.07656 0.04259  0.15821  3  DG A O6    
79  N N1    . DG A 3  ? 0.41166 0.48990 0.27638 -0.06290 0.08120  0.11944  3  DG A N1    
80  C C2    . DG A 3  ? 0.41238 0.47751 0.26237 -0.06427 0.09888  0.08741  3  DG A C2    
81  N N2    . DG A 3  ? 0.42261 0.49185 0.24665 -0.05488 0.11933  0.07758  3  DG A N2    
82  N N3    . DG A 3  ? 0.41028 0.45947 0.27323 -0.07455 0.09776  0.06656  3  DG A N3    
83  C C4    . DG A 3  ? 0.40816 0.44800 0.29457 -0.08201 0.07934  0.07868  3  DG A C4    
95  P P     . DG A 4  ? 0.40308 0.50590 0.40076 -0.09476 0.10395  0.00392  4  DG A P     
96  O OP1   . DG A 4  ? 0.38842 0.49440 0.39378 -0.10280 0.12016  -0.02608 4  DG A OP1   
97  O OP2   . DG A 4  ? 0.47485 0.59262 0.51240 -0.08855 0.08820  0.03117  4  DG A OP2   
98  O "O5'" . DG A 4  ? 0.40280 0.54263 0.37732 -0.08936 0.09469  0.01861  4  DG A "O5'" 
99  C "C5'" . DG A 4  ? 0.41752 0.53911 0.34904 -0.09144 0.10978  0.00025  4  DG A "C5'" 
100 C "C4'" . DG A 4  ? 0.38752 0.54494 0.30085 -0.08217 0.10305  0.01869  4  DG A "C4'" 
101 O "O4'" . DG A 4  ? 0.39119 0.53340 0.29678 -0.07484 0.09729  0.04599  4  DG A "O4'" 
102 C "C3'" . DG A 4  ? 0.37647 0.59980 0.31715 -0.07644 0.08446  0.03922  4  DG A "C3'" 
103 O "O3'" . DG A 4  ? 0.49337 0.74741 0.40431 -0.07334 0.08820  0.03121  4  DG A "O3'" 
104 C "C2'" . DG A 4  ? 0.38490 0.61554 0.34401 -0.06760 0.07072  0.07904  4  DG A "C2'" 
105 C "C1'" . DG A 4  ? 0.37151 0.56386 0.29644 -0.06577 0.08152  0.07898  4  DG A "C1'" 
106 N N9    . DG A 4  ? 0.36492 0.54613 0.30706 -0.06471 0.06950  0.10782  4  DG A N9    
107 C C8    . DG A 4  ? 0.36123 0.52399 0.33454 -0.07171 0.05776  0.11525  4  DG A C8    
108 N N7    . DG A 4  ? 0.36213 0.51740 0.34590 -0.07342 0.04618  0.13991  4  DG A N7    
109 C C5    . DG A 4  ? 0.36189 0.53793 0.32456 -0.06465 0.05103  0.15346  4  DG A C5    
110 C C6    . DG A 4  ? 0.36223 0.54773 0.33168 -0.06252 0.04280  0.18321  4  DG A C6    
111 O O6    . DG A 4  ? 0.36398 0.54092 0.35922 -0.07189 0.02613  0.20172  4  DG A O6    
112 N N1    . DG A 4  ? 0.36531 0.57234 0.31066 -0.04884 0.05649  0.19055  4  DG A N1    
113 C C2    . DG A 4  ? 0.37305 0.58474 0.28608 -0.04046 0.07569  0.16771  4  DG A C2    
114 N N2    . DG A 4  ? 0.38533 0.60308 0.28053 -0.02474 0.08710  0.17105  4  DG A N2    
115 N N3    . DG A 4  ? 0.37459 0.57731 0.28009 -0.04663 0.08045  0.13676  4  DG A N3    
116 C C4    . DG A 4  ? 0.36594 0.55403 0.30000 -0.05784 0.06736  0.13322  4  DG A C4    
128 P P     . DT A 5  ? 0.41312 0.73882 0.33723 -0.06945 0.07091  0.04190  5  DT A P     
129 O OP1   . DT A 5  ? 0.48016 0.81366 0.35496 -0.06960 0.08161  0.02070  5  DT A OP1   
130 O OP2   . DT A 5  ? 0.44069 0.78495 0.40767 -0.07759 0.06101  0.03401  5  DT A OP2   
131 O "O5'" . DT A 5  ? 0.37169 0.72766 0.32292 -0.05457 0.05548  0.09227  5  DT A "O5'" 
132 C "C5'" . DT A 5  ? 0.37886 0.76106 0.30822 -0.04087 0.05614  0.11882  5  DT A "C5'" 
133 C "C4'" . DT A 5  ? 0.46789 0.80995 0.35686 -0.03813 0.07602  0.10825  5  DT A "C4'" 
134 O "O4'" . DT A 5  ? 0.38125 0.68541 0.28879 -0.03913 0.07580  0.12483  5  DT A "O4'" 
135 C "C3'" . DT A 5  ? 0.50102 0.87348 0.36284 -0.02170 0.08311  0.13071  5  DT A "C3'" 
136 O "O3'" . DT A 5  ? 0.53236 0.85563 0.35960 -0.01769 0.10173  0.10613  5  DT A "O3'" 
137 C "C2'" . DT A 5  ? 0.40404 0.78243 0.30867 -0.01363 0.07112  0.17481  5  DT A "C2'" 
138 C "C1'" . DT A 5  ? 0.37291 0.70168 0.28920 -0.02646 0.07273  0.16581  5  DT A "C1'" 
139 N N1    . DT A 5  ? 0.35342 0.67861 0.31729 -0.03184 0.05573  0.19256  5  DT A N1    
140 C C2    . DT A 5  ? 0.34847 0.67434 0.33038 -0.02881 0.05133  0.22504  5  DT A C2    
141 O O2    . DT A 5  ? 0.35793 0.68178 0.32914 -0.01639 0.05665  0.22558  5  DT A O2    
142 N N3    . DT A 5  ? 0.33861 0.65289 0.36308 -0.03884 0.03534  0.24298  5  DT A N3    
143 C C4    . DT A 5  ? 0.33542 0.63246 0.38366 -0.04763 0.02713  0.23119  5  DT A C4    
144 O O4    . DT A 5  ? 0.33527 0.61481 0.41934 -0.05592 0.01564  0.24666  5  DT A O4    
145 C C5    . DT A 5  ? 0.33707 0.63920 0.36856 -0.04667 0.03387  0.20018  5  DT A C5    
146 C C7    . DT A 5  ? 0.35345 0.64374 0.41495 -0.05245 0.02879  0.18882  5  DT A C7    
147 C C6    . DT A 5  ? 0.34539 0.66226 0.33666 -0.04096 0.04592  0.18179  5  DT A C6    
160 P P     . DG A 6  ? 0.73165 0.54365 0.78834 -0.02049 0.03367  0.16528  6  DG A P     
161 O OP1   . DG A 6  ? 0.77543 0.54386 0.84178 -0.01854 0.02874  0.18927  6  DG A OP1   
162 O OP2   . DG A 6  ? 0.62167 0.43364 0.67084 -0.03560 0.04263  0.13078  6  DG A OP2   
163 O "O5'" . DG A 6  ? 0.65383 0.47798 0.72619 0.00697  0.03229  0.14886  6  DG A "O5'" 
164 C "C5'" . DG A 6  ? 0.46269 0.28054 0.53891 0.00860  0.04125  0.11330  6  DG A "C5'" 
165 C "C4'" . DG A 6  ? 0.46415 0.30110 0.55581 0.03138  0.04085  0.10250  6  DG A "C4'" 
166 O "O4'" . DG A 6  ? 0.40529 0.29149 0.48720 0.03555  0.03146  0.11562  6  DG A "O4'" 
167 C "C3'" . DG A 6  ? 0.43881 0.28302 0.52601 0.02787  0.05046  0.06764  6  DG A "C3'" 
168 O "O3'" . DG A 6  ? 0.46184 0.30040 0.57378 0.04665  0.05632  0.05368  6  DG A "O3'" 
169 C "C2'" . DG A 6  ? 0.40755 0.29789 0.47493 0.02184  0.04495  0.06691  6  DG A "C2'" 
170 C "C1'" . DG A 6  ? 0.35946 0.27400 0.43342 0.03360  0.03466  0.09187  6  DG A "C1'" 
171 N N9    . DG A 6  ? 0.34607 0.29748 0.40085 0.02383  0.02790  0.09691  6  DG A N9    
172 C C8    . DG A 6  ? 0.33314 0.29028 0.36983 0.00687  0.02817  0.09400  6  DG A C8    
173 N N7    . DG A 6  ? 0.32083 0.31494 0.34819 0.00393  0.02262  0.09394  6  DG A N7    
174 C C5    . DG A 6  ? 0.30232 0.31593 0.33926 0.01689  0.01769  0.09775  6  DG A C5    
175 C C6    . DG A 6  ? 0.28573 0.34039 0.31945 0.01772  0.01079  0.09551  6  DG A C6    
176 O O6    . DG A 6  ? 0.25510 0.33493 0.27752 0.00891  0.00859  0.08772  6  DG A O6    
177 N N1    . DG A 6  ? 0.24594 0.31534 0.29487 0.03034  0.00657  0.09978  6  DG A N1    
178 C C2    . DG A 6  ? 0.26372 0.31248 0.33218 0.04384  0.00941  0.10463  6  DG A C2    
179 N N2    . DG A 6  ? 0.28977 0.36602 0.37663 0.05616  0.00426  0.10695  6  DG A N2    
180 N N3    . DG A 6  ? 0.29807 0.30548 0.37121 0.04526  0.01694  0.10412  6  DG A N3    
181 C C4    . DG A 6  ? 0.31227 0.30312 0.36723 0.02983  0.02049  0.10087  6  DG A C4    
193 P P     . DG A 7  ? 0.53548 0.38633 0.64248 0.04185  0.06863  0.01780  7  DG A P     
194 O OP1   . DG A 7  ? 0.65880 0.48527 0.79725 0.05827  0.07885  -0.00081 7  DG A OP1   
195 O OP2   . DG A 7  ? 0.46228 0.31441 0.53893 0.01729  0.06969  0.00749  7  DG A OP2   
196 O "O5'" . DG A 7  ? 0.41695 0.31678 0.52150 0.04787  0.06450  0.02088  7  DG A "O5'" 
197 C "C5'" . DG A 7  ? 0.39494 0.31386 0.52278 0.06755  0.05741  0.03742  7  DG A "C5'" 
198 C "C4'" . DG A 7  ? 0.41226 0.37814 0.53325 0.06434  0.05396  0.03592  7  DG A "C4'" 
199 O "O4'" . DG A 7  ? 0.31723 0.29590 0.41666 0.05357  0.04246  0.05281  7  DG A "O4'" 
200 C "C3'" . DG A 7  ? 0.37538 0.35405 0.48001 0.04902  0.06389  0.01278  7  DG A "C3'" 
201 O "O3'" . DG A 7  ? 0.42946 0.44679 0.54748 0.05284  0.06638  0.00687  7  DG A "O3'" 
202 C "C2'" . DG A 7  ? 0.34617 0.32430 0.42071 0.03114  0.05579  0.02052  7  DG A "C2'" 
203 C "C1'" . DG A 7  ? 0.31432 0.30923 0.39482 0.03847  0.04374  0.04054  7  DG A "C1'" 
204 N N9    . DG A 7  ? 0.29533 0.29091 0.35537 0.02692  0.03583  0.04819  7  DG A N9    
205 C C8    . DG A 7  ? 0.30563 0.28068 0.35083 0.01647  0.03640  0.04773  7  DG A C8    
206 N N7    . DG A 7  ? 0.30898 0.29859 0.34305 0.00946  0.02939  0.05174  7  DG A N7    
207 C C5    . DG A 7  ? 0.25890 0.27595 0.29858 0.01432  0.02401  0.05315  7  DG A C5    
208 C C6    . DG A 7  ? 0.25199 0.29374 0.28676 0.01043  0.01676  0.05139  7  DG A C6    
209 O O6    . DG A 7  ? 0.29226 0.33887 0.31874 0.00425  0.01426  0.04813  7  DG A O6    
210 N N1    . DG A 7  ? 0.26120 0.32781 0.30532 0.01424  0.01293  0.04976  7  DG A N1    
211 C C2    . DG A 7  ? 0.27027 0.34251 0.32916 0.02187  0.01565  0.05150  7  DG A C2    
212 N N2    . DG A 7  ? 0.22209 0.32655 0.29095 0.02216  0.01058  0.04851  7  DG A N2    
213 N N3    . DG A 7  ? 0.18709 0.23885 0.25369 0.02845  0.02340  0.05237  7  DG A N3    
214 C C4    . DG A 7  ? 0.28702 0.30938 0.34213 0.02378  0.02726  0.05236  7  DG A C4    
226 P P     . DT A 8  ? 0.42041 0.45648 0.53946 0.04523  0.08268  -0.01867 8  DT A P     
227 O OP1   . DT A 8  ? 0.59174 0.66633 0.74485 0.06007  0.08588  -0.02265 8  DT A OP1   
228 O OP2   . DT A 8  ? 0.42403 0.43088 0.53581 0.04176  0.09368  -0.03719 8  DT A OP2   
229 O "O5'" . DT A 8  ? 0.41322 0.46380 0.50192 0.02135  0.07866  -0.01433 8  DT A "O5'" 
230 C "C5'" . DT A 8  ? 0.41383 0.45245 0.47291 0.00256  0.08299  -0.02181 8  DT A "C5'" 
231 C "C4'" . DT A 8  ? 0.29545 0.32767 0.33185 -0.01102 0.06949  -0.00617 8  DT A "C4'" 
232 O "O4'" . DT A 8  ? 0.33389 0.33944 0.35406 -0.01425 0.06430  -0.00413 8  DT A "O4'" 
233 C "C3'" . DT A 8  ? 0.28417 0.32978 0.30037 -0.03210 0.07035  -0.00441 8  DT A "C3'" 
234 O "O3'" . DT A 8  ? 0.24552 0.30067 0.26874 -0.03558 0.06155  0.00651  8  DT A "O3'" 
235 C "C2'" . DT A 8  ? 0.30659 0.33010 0.29553 -0.04270 0.06251  0.00065  8  DT A "C2'" 
236 C "C1'" . DT A 8  ? 0.31855 0.32229 0.31686 -0.02879 0.05559  0.00336  8  DT A "C1'" 
237 N N1    . DT A 8  ? 0.33128 0.31876 0.31419 -0.03446 0.05311  0.00010  8  DT A N1    
238 C C2    . DT A 8  ? 0.30180 0.28264 0.27675 -0.03750 0.03969  0.01011  8  DT A C2    
239 O O2    . DT A 8  ? 0.29881 0.28235 0.27881 -0.03494 0.03038  0.01957  8  DT A O2    
240 N N3    . DT A 8  ? 0.32487 0.29833 0.28926 -0.04374 0.03781  0.00524  8  DT A N3    
241 C C4    . DT A 8  ? 0.32682 0.29468 0.28579 -0.04950 0.04804  -0.01025 8  DT A C4    
242 O O4    . DT A 8  ? 0.32314 0.28733 0.27333 -0.05818 0.04490  -0.01565 8  DT A O4    
243 C C5    . DT A 8  ? 0.34596 0.31569 0.31453 -0.04446 0.06289  -0.02304 8  DT A C5    
244 C C7    . DT A 8  ? 0.43122 0.39301 0.39952 -0.04868 0.07629  -0.04703 8  DT A C7    
245 C C6    . DT A 8  ? 0.36296 0.34454 0.34428 -0.03602 0.06451  -0.01636 8  DT A C6    
258 P P     . DC A 9  ? 0.38421 0.46088 0.40310 -0.05584 0.06553  0.00946  9  DC A P     
259 O OP1   . DC A 9  ? 0.35013 0.46303 0.39348 -0.04980 0.07899  -0.00310 9  DC A OP1   
260 O OP2   . DC A 9  ? 0.44056 0.50749 0.42868 -0.07612 0.06533  0.01653  9  DC A OP2   
261 O "O5'" . DC A 9  ? 0.35594 0.42519 0.38334 -0.05739 0.05106  0.01935  9  DC A "O5'" 
262 C "C5'" . DC A 9  ? 0.30876 0.40187 0.36136 -0.04858 0.05011  0.01502  9  DC A "C5'" 
263 C "C4'" . DC A 9  ? 0.30861 0.39165 0.36450 -0.05204 0.03613  0.01876  9  DC A "C4'" 
264 O "O4'" . DC A 9  ? 0.27042 0.33201 0.31936 -0.03887 0.02786  0.02047  9  DC A "O4'" 
265 C "C3'" . DC A 9  ? 0.29056 0.35221 0.33543 -0.07330 0.03057  0.02578  9  DC A "C3'" 
266 O "O3'" . DC A 9  ? 0.24094 0.30995 0.30203 -0.08049 0.02387  0.02082  9  DC A "O3'" 
267 C "C2'" . DC A 9  ? 0.28909 0.31551 0.31872 -0.06682 0.02085  0.03157  9  DC A "C2'" 
268 C "C1'" . DC A 9  ? 0.25679 0.29127 0.29542 -0.04653 0.01840  0.02405  9  DC A "C1'" 
269 N N1    . DC A 9  ? 0.25406 0.27056 0.28040 -0.03739 0.01593  0.02655  9  DC A N1    
270 C C2    . DC A 9  ? 0.26405 0.27016 0.29283 -0.03074 0.00600  0.02406  9  DC A C2    
271 O O2    . DC A 9  ? 0.31449 0.32385 0.35487 -0.03168 -0.00005 0.01743  9  DC A O2    
272 N N3    . DC A 9  ? 0.27511 0.27213 0.29557 -0.02470 0.00427  0.02566  9  DC A N3    
273 C C4    . DC A 9  ? 0.29411 0.28780 0.30265 -0.02659 0.01137  0.02861  9  DC A C4    
274 N N4    . DC A 9  ? 0.24283 0.23027 0.24485 -0.02410 0.00925  0.02844  9  DC A N4    
275 C C5    . DC A 9  ? 0.30542 0.30664 0.31070 -0.03224 0.02211  0.02801  9  DC A C5    
276 C C6    . DC A 9  ? 0.30295 0.31782 0.31826 -0.03669 0.02441  0.02745  9  DC A C6    
288 P P     . DT A 10 ? 0.33183 0.37626 0.39132 -0.10514 0.01807  0.02742  10 DT A P     
289 O OP1   . DT A 10 ? 0.27236 0.34098 0.35425 -0.11565 0.01675  0.01565  10 DT A OP1   
290 O OP2   . DT A 10 ? 0.35264 0.39286 0.39350 -0.12329 0.02599  0.04230  10 DT A OP2   
291 O "O5'" . DT A 10 ? 0.29328 0.29468 0.34823 -0.09549 0.00381  0.02892  10 DT A "O5'" 
292 C "C5'" . DT A 10 ? 0.39218 0.35923 0.45460 -0.10894 -0.00640 0.03160  10 DT A "C5'" 
293 C "C4'" . DT A 10 ? 0.39466 0.33767 0.46639 -0.09140 -0.01822 0.02086  10 DT A "C4'" 
294 O "O4'" . DT A 10 ? 0.33702 0.31256 0.42127 -0.08072 -0.01649 -0.00137 10 DT A "O4'" 
295 C "C3'" . DT A 10 ? 0.36990 0.30337 0.42783 -0.07406 -0.02127 0.02912  10 DT A "C3'" 
296 O "O3'" . DT A 10 ? 0.38657 0.28555 0.45431 -0.06684 -0.03456 0.02966  10 DT A "O3'" 
297 C "C2'" . DT A 10 ? 0.35324 0.31977 0.41300 -0.05725 -0.01566 0.01470  10 DT A "C2'" 
298 C "C1'" . DT A 10 ? 0.35979 0.34328 0.43779 -0.06000 -0.01710 -0.00471 10 DT A "C1'" 
299 N N1    . DT A 10 ? 0.31287 0.33946 0.39070 -0.05295 -0.01066 -0.01097 10 DT A N1    
300 C C2    . DT A 10 ? 0.34009 0.38625 0.41970 -0.04032 -0.01307 -0.02301 10 DT A C2    
301 O O2    . DT A 10 ? 0.35428 0.38750 0.43803 -0.03398 -0.01826 -0.03373 10 DT A O2    
302 N N3    . DT A 10 ? 0.31718 0.40240 0.39501 -0.03513 -0.00937 -0.02108 10 DT A N3    
303 C C4    . DT A 10 ? 0.25369 0.35953 0.33463 -0.03716 -0.00409 -0.01166 10 DT A C4    
304 O O4    . DT A 10 ? 0.24922 0.38833 0.33288 -0.02862 -0.00391 -0.00770 10 DT A O4    
305 C C5    . DT A 10 ? 0.22874 0.31766 0.31100 -0.05006 0.00079  -0.00553 10 DT A C5    
306 C C7    . DT A 10 ? 0.25421 0.37180 0.34450 -0.05249 0.00913  -0.00027 10 DT A C7    
307 C C6    . DT A 10 ? 0.28187 0.33251 0.35941 -0.05918 -0.00262 -0.00382 10 DT A C6    
320 P P     . DA A 11 ? 0.42499 0.29999 0.47796 -0.06406 -0.04350 0.05311  11 DA A P     
321 O OP1   . DA A 11 ? 0.42392 0.26041 0.49869 -0.05534 -0.06018 0.05346  11 DA A OP1   
322 O OP2   . DA A 11 ? 0.46576 0.34503 0.49488 -0.08555 -0.03658 0.07437  11 DA A OP2   
323 O "O5'" . DA A 11 ? 0.37112 0.27283 0.41584 -0.04673 -0.03908 0.04565  11 DA A "O5'" 
324 C "C5'" . DA A 11 ? 0.36036 0.26992 0.42260 -0.02887 -0.04276 0.02718  11 DA A "C5'" 
325 C "C4'" . DA A 11 ? 0.30282 0.22894 0.35451 -0.01923 -0.04157 0.02976  11 DA A "C4'" 
326 O "O4'" . DA A 11 ? 0.29284 0.24106 0.32744 -0.02444 -0.02768 0.03040  11 DA A "O4'" 
327 C "C3'" . DA A 11 ? 0.26765 0.17848 0.30759 -0.02181 -0.05178 0.05006  11 DA A "C3'" 
328 O "O3'" . DA A 11 ? 0.37332 0.27173 0.43522 -0.00753 -0.06697 0.04837  11 DA A "O3'" 
329 C "C2'" . DA A 11 ? 0.34114 0.27596 0.36228 -0.02282 -0.04285 0.04972  11 DA A "C2'" 
330 C "C1'" . DA A 11 ? 0.29977 0.24998 0.31680 -0.02669 -0.02673 0.04020  11 DA A "C1'" 
331 N N9    . DA A 11 ? 0.31563 0.26840 0.31456 -0.04038 -0.01699 0.04811  11 DA A N9    
332 C C8    . DA A 11 ? 0.30939 0.26402 0.31010 -0.05031 -0.01090 0.04938  11 DA A C8    
333 N N7    . DA A 11 ? 0.29767 0.26455 0.28323 -0.06077 0.00038  0.05248  11 DA A N7    
334 C C5    . DA A 11 ? 0.29520 0.26407 0.26674 -0.05782 0.00117  0.05185  11 DA A C5    
335 C C6    . DA A 11 ? 0.33867 0.31939 0.29166 -0.06562 0.01168  0.04852  11 DA A C6    
336 N N6    . DA A 11 ? 0.36783 0.36461 0.31431 -0.07626 0.02515  0.04510  11 DA A N6    
337 N N1    . DA A 11 ? 0.33163 0.31178 0.27517 -0.06336 0.00895  0.04493  11 DA A N1    
338 C C2    . DA A 11 ? 0.33514 0.30772 0.28860 -0.05353 -0.00334 0.04681  11 DA A C2    
339 N N3    . DA A 11 ? 0.31563 0.28029 0.28801 -0.04362 -0.01276 0.04894  11 DA A N3    
340 C C4    . DA A 11 ? 0.29998 0.26086 0.27973 -0.04639 -0.00996 0.05058  11 DA A C4    
352 P P     . DT A 12 ? 0.44110 0.31097 0.50262 -0.00844 -0.08647 0.07478  12 DT A P     
353 O OP1   . DT A 12 ? 0.52668 0.38665 0.62597 0.01390  -0.10057 0.06319  12 DT A OP1   
354 O OP2   . DT A 12 ? 0.42243 0.26584 0.46865 -0.02858 -0.08728 0.09597  12 DT A OP2   
355 O "O5'" . DT A 12 ? 0.42657 0.32164 0.46291 -0.01229 -0.08747 0.08661  12 DT A "O5'" 
356 C "C5'" . DT A 12 ? 0.38115 0.30483 0.42682 -0.00027 -0.08665 0.07187  12 DT A "C5'" 
357 C "C4'" . DT A 12 ? 0.29249 0.23662 0.30952 -0.01210 -0.08534 0.08152  12 DT A "C4'" 
358 O "O4'" . DT A 12 ? 0.33079 0.27657 0.32090 -0.02902 -0.06724 0.08004  12 DT A "O4'" 
359 C "C3'" . DT A 12 ? 0.41142 0.34917 0.41522 -0.01765 -0.10475 0.10896  12 DT A "C3'" 
360 O "O3'" . DT A 12 ? 0.37112 0.34039 0.36541 -0.01959 -0.10964 0.10773  12 DT A "O3'" 
361 C "C2'" . DT A 12 ? 0.43196 0.35870 0.40256 -0.04030 -0.09531 0.12324  12 DT A "C2'" 
362 C "C1'" . DT A 12 ? 0.40429 0.34901 0.36508 -0.04601 -0.07103 0.09963  12 DT A "C1'" 
363 N N1    . DT A 12 ? 0.34633 0.28543 0.29210 -0.06080 -0.05526 0.10029  12 DT A N1    
364 C C2    . DT A 12 ? 0.38998 0.34882 0.31080 -0.07472 -0.03933 0.09313  12 DT A C2    
365 O O2    . DT A 12 ? 0.39771 0.37395 0.30536 -0.07779 -0.03739 0.08548  12 DT A O2    
366 N N3    . DT A 12 ? 0.38429 0.34440 0.29977 -0.08528 -0.02513 0.09156  12 DT A N3    
367 C C4    . DT A 12 ? 0.38262 0.32716 0.31266 -0.08686 -0.02583 0.09760  12 DT A C4    
368 O O4    . DT A 12 ? 0.36157 0.31626 0.28782 -0.09877 -0.01227 0.09502  12 DT A O4    
369 C C5    . DT A 12 ? 0.38880 0.30763 0.34262 -0.07393 -0.04298 0.10345  12 DT A C5    
370 C C7    . DT A 12 ? 0.33965 0.23663 0.31274 -0.07671 -0.04538 0.10540  12 DT A C7    
371 C C6    . DT A 12 ? 0.38748 0.30516 0.34884 -0.06019 -0.05617 0.10380  12 DT A C6    
384 P P     . DT A 13 ? 0.45733 0.43647 0.44020 -0.02268 -0.13432 0.13501  13 DT A P     
385 O OP1   . DT A 13 ? 0.42032 0.43960 0.41159 -0.01867 -0.13671 0.11934  13 DT A OP1   
386 O OP2   . DT A 13 ? 0.52695 0.47413 0.53297 -0.00877 -0.15636 0.15845  13 DT A OP2   
387 O "O5'" . DT A 13 ? 0.47833 0.46068 0.41168 -0.05132 -0.12570 0.14928  13 DT A "O5'" 
388 C "C5'" . DT A 13 ? 0.47035 0.47448 0.37428 -0.06525 -0.14243 0.17286  13 DT A "C5'" 
389 C "C4'" . DT A 13 ? 0.43014 0.45672 0.28911 -0.09295 -0.12318 0.16388  13 DT A "C4'" 
390 O "O4'" . DT A 13 ? 0.43365 0.47285 0.29901 -0.09214 -0.10063 0.12637  13 DT A "O4'" 
391 C "C3'" . DT A 13 ? 0.48011 0.48762 0.31941 -0.10867 -0.10785 0.17223  13 DT A "C3'" 
392 O "O3'" . DT A 13 ? 0.53347 0.56995 0.33520 -0.13283 -0.10013 0.17390  13 DT A "O3'" 
393 C "C2'" . DT A 13 ? 0.45408 0.45422 0.31115 -0.10146 -0.08142 0.13830  13 DT A "C2'" 
394 C "C1'" . DT A 13 ? 0.42178 0.44887 0.27636 -0.10118 -0.07563 0.11330  13 DT A "C1'" 
395 N N1    . DT A 13 ? 0.36449 0.38333 0.24477 -0.08815 -0.05912 0.08611  13 DT A N1    
396 C C2    . DT A 13 ? 0.39021 0.41117 0.26203 -0.09562 -0.03559 0.06434  13 DT A C2    
397 O O2    . DT A 13 ? 0.42332 0.45636 0.26930 -0.11208 -0.02482 0.06025  13 DT A O2    
398 N N3    . DT A 13 ? 0.38256 0.39334 0.27901 -0.08262 -0.02516 0.04744  13 DT A N3    
399 C C4    . DT A 13 ? 0.37506 0.38058 0.29906 -0.06653 -0.03322 0.04775  13 DT A C4    
400 O O4    . DT A 13 ? 0.38392 0.38490 0.32398 -0.05908 -0.02283 0.03534  13 DT A O4    
401 C C5    . DT A 13 ? 0.37370 0.38193 0.30754 -0.05888 -0.05501 0.06414  13 DT A C5    
402 C C7    . DT A 13 ? 0.36414 0.37452 0.33140 -0.04050 -0.06284 0.05938  13 DT A C7    
403 C C6    . DT A 13 ? 0.38132 0.39291 0.29493 -0.06843 -0.06800 0.08359  13 DT A C6    
416 P P     . DC A 14 ? 0.54691 0.57755 0.33476 -0.14982 -0.09255 0.18962  14 DC A P     
417 O OP1   . DC A 14 ? 0.54330 0.61568 0.29750 -0.17147 -0.08933 0.18774  14 DC A OP1   
418 O OP2   . DC A 14 ? 0.63555 0.62838 0.44863 -0.13776 -0.11049 0.21638  14 DC A OP2   
419 O "O5'" . DC A 14 ? 0.58689 0.61131 0.37599 -0.15497 -0.06545 0.16853  14 DC A "O5'" 
420 C "C5'" . DC A 14 ? 0.59916 0.64820 0.37428 -0.16144 -0.04344 0.13754  14 DC A "C5'" 
421 C "C4'" . DC A 14 ? 0.54842 0.59057 0.33444 -0.16246 -0.02037 0.12330  14 DC A "C4'" 
422 O "O4'" . DC A 14 ? 0.45301 0.45983 0.27567 -0.14212 -0.02739 0.12765  14 DC A "O4'" 
423 C "C3'" . DC A 14 ? 0.53997 0.59399 0.31787 -0.17897 -0.01317 0.13179  14 DC A "C3'" 
424 O "O3'" . DC A 14 ? 0.50627 0.58543 0.28256 -0.18537 0.01306  0.10434  14 DC A "O3'" 
425 C "C2'" . DC A 14 ? 0.54813 0.56502 0.35056 -0.17179 -0.02418 0.15325  14 DC A "C2'" 
426 C "C1'" . DC A 14 ? 0.49662 0.49005 0.32455 -0.15137 -0.02498 0.14271  14 DC A "C1'" 
427 N N1    . DC A 14 ? 0.54848 0.50219 0.40353 -0.13667 -0.04575 0.16021  14 DC A N1    
428 C C2    . DC A 14 ? 0.54765 0.47932 0.42573 -0.13664 -0.04245 0.16093  14 DC A C2    
429 O O2    . DC A 14 ? 0.57908 0.52875 0.45440 -0.14920 -0.02367 0.15066  14 DC A O2    
430 N N3    . DC A 14 ? 0.63317 0.52759 0.53948 -0.12238 -0.05991 0.16923  14 DC A N3    
431 C C4    . DC A 14 ? 0.61037 0.49222 0.52612 -0.10533 -0.07993 0.17719  14 DC A C4    
432 N N4    . DC A 14 ? 0.65708 0.50433 0.60727 -0.08831 -0.09488 0.17864  14 DC A N4    
433 C C5    . DC A 14 ? 0.59973 0.50872 0.49351 -0.10472 -0.08486 0.17943  14 DC A C5    
434 C C6    . DC A 14 ? 0.57330 0.51629 0.43576 -0.12188 -0.06723 0.16989  14 DC A C6    
446 P P     . DA A 15 ? 0.69210 0.81581 0.44149 -0.20286 0.02536  0.08444  15 DA A P     
447 O OP1   . DA A 15 ? 0.66024 0.79691 0.38755 -0.22054 0.00990  0.11072  15 DA A OP1   
448 O OP2   . DA A 15 ? 0.73184 0.87513 0.49440 -0.20198 0.05269  0.05400  15 DA A OP2   
449 O "O5'" . DA A 15 ? 0.55265 0.67939 0.29425 -0.19624 0.02213  0.06653  15 DA A "O5'" 
450 C "C5'" . DA A 15 ? 0.49754 0.62907 0.24814 -0.18895 0.04327  0.03004  15 DA A "C5'" 
451 C "C4'" . DA A 15 ? 0.46788 0.58327 0.22333 -0.17775 0.03353  0.02162  15 DA A "C4'" 
452 O "O4'" . DA A 15 ? 0.44277 0.52319 0.22655 -0.15737 0.01550  0.04368  15 DA A "O4'" 
453 C "C3'" . DA A 15 ? 0.43873 0.54607 0.21773 -0.16509 0.05217  -0.01760 15 DA A "C3'" 
454 O "O3'" . DA A 15 ? 0.45881 0.56801 0.23046 -0.16874 0.04364  -0.02960 15 DA A "O3'" 
455 C "C2'" . DA A 15 ? 0.41907 0.49208 0.23849 -0.13968 0.05102  -0.01030 15 DA A "C2'" 
456 C "C1'" . DA A 15 ? 0.40475 0.46320 0.22426 -0.13607 0.02606  0.02441  15 DA A "C1'" 
457 N N9    . DA A 15 ? 0.44981 0.49025 0.29003 -0.12604 0.02301  0.04169  15 DA A N9    
458 C C8    . DA A 15 ? 0.43339 0.45032 0.29286 -0.11239 0.00564  0.05912  15 DA A C8    
459 N N7    . DA A 15 ? 0.40040 0.40589 0.27439 -0.10949 0.00621  0.06883  15 DA A N7    
460 C C5    . DA A 15 ? 0.40916 0.43541 0.27314 -0.12264 0.02467  0.06029  15 DA A C5    
461 C C6    . DA A 15 ? 0.44546 0.47829 0.31878 -0.12905 0.03408  0.06338  15 DA A C6    
462 N N6    . DA A 15 ? 0.39446 0.40746 0.28750 -0.12431 0.02486  0.07589  15 DA A N6    
463 N N1    . DA A 15 ? 0.50578 0.57049 0.36991 -0.14169 0.05412  0.04943  15 DA A N1    
464 C C2    . DA A 15 ? 0.50864 0.59353 0.35366 -0.14738 0.06429  0.03116  15 DA A C2    
465 N N3    . DA A 15 ? 0.47567 0.55333 0.30830 -0.14435 0.05637  0.02558  15 DA A N3    
466 C C4    . DA A 15 ? 0.43130 0.48004 0.27499 -0.13177 0.03596  0.04248  15 DA A C4    
478 P P     . DT A 16 ? 0.55610 0.64766 0.35107 -0.15989 0.05761  -0.06669 16 DT A P     
479 O OP1   . DT A 16 ? 0.49803 0.61513 0.26577 -0.18115 0.05398  -0.08484 16 DT A OP1   
480 O OP2   . DT A 16 ? 0.55523 0.63789 0.37274 -0.14856 0.08107  -0.08857 16 DT A OP2   
481 O "O5'" . DT A 16 ? 0.44231 0.50044 0.26875 -0.13923 0.04365  -0.04923 16 DT A "O5'" 
482 C "C5'" . DT A 16 ? 0.41111 0.47432 0.23319 -0.14033 0.02097  -0.02809 16 DT A "C5'" 
483 C "C4'" . DT A 16 ? 0.36675 0.40424 0.22231 -0.11968 0.01415  -0.01716 16 DT A "C4'" 
484 O "O4'" . DT A 16 ? 0.40755 0.43170 0.27576 -0.10625 0.01471  -0.00016 16 DT A "O4'" 
485 C "C3'" . DT A 16 ? 0.42274 0.43799 0.30148 -0.11258 0.02753  -0.03717 16 DT A "C3'" 
486 O "O3'" . DT A 16 ? 0.35207 0.36397 0.24787 -0.10616 0.01563  -0.02764 16 DT A "O3'" 
487 C "C2'" . DT A 16 ? 0.37289 0.37096 0.26849 -0.09729 0.04008  -0.03517 16 DT A "C2'" 
488 C "C1'" . DT A 16 ? 0.36322 0.36683 0.25797 -0.09124 0.02624  -0.00900 16 DT A "C1'" 
489 N N1    . DT A 16 ? 0.36085 0.36285 0.26165 -0.08515 0.03397  -0.00298 16 DT A N1    
490 C C2    . DT A 16 ? 0.31034 0.30583 0.22283 -0.07621 0.02336  0.01559  16 DT A C2    
491 O O2    . DT A 16 ? 0.33834 0.32871 0.25903 -0.06987 0.00955  0.02483  16 DT A O2    
492 N N3    . DT A 16 ? 0.32895 0.32715 0.24704 -0.07513 0.03039  0.01917  16 DT A N3    
493 C C4    . DT A 16 ? 0.35954 0.37189 0.27430 -0.08085 0.04713  0.00693  16 DT A C4    
494 O O4    . DT A 16 ? 0.39860 0.41991 0.32179 -0.08125 0.05258  0.01065  16 DT A O4    
495 C C5    . DT A 16 ? 0.42794 0.44779 0.33153 -0.08746 0.05866  -0.01435 16 DT A C5    
496 C C7    . DT A 16 ? 0.40450 0.44468 0.30878 -0.09170 0.07913  -0.03500 16 DT A C7    
497 C C6    . DT A 16 ? 0.39356 0.40551 0.28953 -0.09032 0.05129  -0.01863 16 DT A C6    
510 P P     . DA A 17 ? 0.32409 0.31466 0.24283 -0.10281 0.02427  -0.03779 17 DA A P     
511 O OP1   . DA A 17 ? 0.35421 0.36250 0.27603 -0.11349 0.01325  -0.03932 17 DA A OP1   
512 O OP2   . DA A 17 ? 0.33595 0.30363 0.25801 -0.10491 0.04275  -0.05824 17 DA A OP2   
513 O "O5'" . DA A 17 ? 0.35327 0.33408 0.29141 -0.08287 0.02191  -0.01890 17 DA A "O5'" 
514 C "C5'" . DA A 17 ? 0.31596 0.31207 0.26112 -0.07518 0.00691  -0.00371 17 DA A "C5'" 
515 C "C4'" . DA A 17 ? 0.28504 0.27647 0.25119 -0.06421 0.00912  0.00183  17 DA A "C4'" 
516 O "O4'" . DA A 17 ? 0.29697 0.27540 0.26841 -0.05225 0.01571  0.00751  17 DA A "O4'" 
517 C "C3'" . DA A 17 ? 0.24881 0.22989 0.22180 -0.07275 0.01854  -0.00477 17 DA A "C3'" 
518 O "O3'" . DA A 17 ? 0.28486 0.28167 0.27154 -0.07084 0.01501  0.00172  17 DA A "O3'" 
519 C "C2'" . DA A 17 ? 0.27002 0.22468 0.24665 -0.06484 0.03061  -0.00386 17 DA A "C2'" 
520 C "C1'" . DA A 17 ? 0.27568 0.24055 0.25687 -0.05017 0.02535  0.00760  17 DA A "C1'" 
521 N N9    . DA A 17 ? 0.28008 0.23363 0.26547 -0.04035 0.03272  0.00940  17 DA A N9    
522 C C8    . DA A 17 ? 0.29046 0.22636 0.27861 -0.03950 0.04379  0.00067  17 DA A C8    
523 N N7    . DA A 17 ? 0.32727 0.26474 0.32487 -0.02747 0.04769  0.00372  17 DA A N7    
524 C C5    . DA A 17 ? 0.27639 0.23145 0.27454 -0.02301 0.03849  0.01503  17 DA A C5    
525 C C6    . DA A 17 ? 0.24869 0.21705 0.25549 -0.01394 0.03659  0.02099  17 DA A C6    
526 N N6    . DA A 17 ? 0.30217 0.27334 0.32070 -0.00590 0.04366  0.01872  17 DA A N6    
527 N N1    . DA A 17 ? 0.21902 0.20081 0.22567 -0.01351 0.02721  0.02611  17 DA A N1    
528 C C2    . DA A 17 ? 0.29184 0.27551 0.29333 -0.01828 0.02035  0.02566  17 DA A C2    
529 N N3    . DA A 17 ? 0.26629 0.24421 0.26131 -0.02584 0.02053  0.02241  17 DA A N3    
530 C C4    . DA A 17 ? 0.27352 0.23625 0.26525 -0.02958 0.02974  0.01733  17 DA A C4    
542 P P     . DG A 18 ? 0.28467 0.31201 0.27818 -0.08259 0.00726  -0.00378 18 DG A P     
543 O OP1   . DG A 18 ? 0.27551 0.32431 0.26610 -0.07842 -0.00780 -0.00441 18 DG A OP1   
544 O OP2   . DG A 18 ? 0.27235 0.28715 0.26381 -0.10255 0.01586  -0.01215 18 DG A OP2   
545 O "O5'" . DG A 18 ? 0.25064 0.30056 0.26095 -0.07510 0.00717  0.00260  18 DG A "O5'" 
546 C "C5'" . DG A 18 ? 0.24281 0.30635 0.26152 -0.05715 -0.00047 0.00484  18 DG A "C5'" 
547 C "C4'" . DG A 18 ? 0.19121 0.25410 0.21288 -0.05044 0.00695  0.01052  18 DG A "C4'" 
548 O "O4'" . DG A 18 ? 0.22826 0.25857 0.23861 -0.04661 0.01248  0.01758  18 DG A "O4'" 
549 C "C3'" . DG A 18 ? 0.21145 0.28743 0.23513 -0.06417 0.01624  0.01491  18 DG A "C3'" 
550 O "O3'" . DG A 18 ? 0.23990 0.34592 0.27031 -0.05877 0.01815  0.01525  18 DG A "O3'" 
551 C "C2'" . DG A 18 ? 0.21719 0.25363 0.22950 -0.06835 0.02418  0.02600  18 DG A "C2'" 
552 C "C1'" . DG A 18 ? 0.23323 0.25826 0.24278 -0.05083 0.02091  0.02713  18 DG A "C1'" 
553 N N9    . DG A 18 ? 0.25435 0.24567 0.25882 -0.04782 0.02653  0.03283  18 DG A N9    
554 C C8    . DG A 18 ? 0.30719 0.26938 0.30973 -0.05675 0.03303  0.03076  18 DG A C8    
555 N N7    . DG A 18 ? 0.31128 0.24932 0.31631 -0.04741 0.03771  0.03339  18 DG A N7    
556 C C5    . DG A 18 ? 0.26509 0.22062 0.27200 -0.03381 0.03342  0.03963  18 DG A C5    
557 C C6    . DG A 18 ? 0.29942 0.24977 0.31277 -0.02018 0.03490  0.04392  18 DG A C6    
558 O O6    . DG A 18 ? 0.31662 0.24502 0.33828 -0.01390 0.04096  0.04257  18 DG A O6    
559 N N1    . DG A 18 ? 0.28265 0.25929 0.29658 -0.01323 0.02871  0.04666  18 DG A N1    
560 C C2    . DG A 18 ? 0.25854 0.25843 0.26933 -0.01660 0.02277  0.04285  18 DG A C2    
561 N N2    . DG A 18 ? 0.27362 0.29310 0.28790 -0.01004 0.01802  0.04096  18 DG A N2    
562 N N3    . DG A 18 ? 0.24781 0.25410 0.25618 -0.02562 0.02166  0.03832  18 DG A N3    
563 C C4    . DG A 18 ? 0.24416 0.22950 0.24978 -0.03487 0.02681  0.03835  18 DG A C4    
575 P P     . DG A 19 ? 0.25698 0.41603 0.30498 -0.06269 0.01786  0.00280  19 DG A P     
576 O OP1   . DG A 19 ? 0.23488 0.39663 0.29578 -0.05193 0.00552  -0.00831 19 DG A OP1   
577 O OP2   . DG A 19 ? 0.27307 0.44903 0.31930 -0.08608 0.02712  0.00903  19 DG A OP2   
578 O "O5'" . DG A 19 ? 0.21151 0.39700 0.26426 -0.05015 0.01932  -0.00388 19 DG A "O5'" 
579 C "C5'" . DG A 19 ? 0.24414 0.41221 0.30087 -0.03143 0.01133  -0.01064 19 DG A "C5'" 
580 C "C4'" . DG A 19 ? 0.30302 0.47710 0.35089 -0.02817 0.01545  -0.00873 19 DG A "C4'" 
581 O "O4'" . DG A 19 ? 0.31752 0.45528 0.34749 -0.03144 0.01726  0.01123  19 DG A "O4'" 
582 C "C3'" . DG A 19 ? 0.27579 0.49722 0.31975 -0.03925 0.02483  -0.01009 19 DG A "C3'" 
583 O "O3'" . DG A 19 ? 0.21796 0.46332 0.26376 -0.03101 0.02461  -0.02435 19 DG A "O3'" 
584 C "C2'" . DG A 19 ? 0.21534 0.41473 0.23769 -0.05386 0.03010  0.01855  19 DG A "C2'" 
585 C "C1'" . DG A 19 ? 0.26083 0.41372 0.27828 -0.04175 0.02407  0.02629  19 DG A "C1'" 
586 N N9    . DG A 19 ? 0.23280 0.34460 0.24124 -0.04727 0.02619  0.04651  19 DG A N9    
587 C C8    . DG A 19 ? 0.25395 0.34678 0.26143 -0.06078 0.03034  0.05329  19 DG A C8    
588 N N7    . DG A 19 ? 0.25681 0.30739 0.26041 -0.06021 0.03180  0.06608  19 DG A N7    
589 C C5    . DG A 19 ? 0.23533 0.28232 0.23835 -0.04432 0.02798  0.06909  19 DG A C5    
590 C C6    . DG A 19 ? 0.31185 0.32809 0.31701 -0.03420 0.02774  0.07924  19 DG A C6    
591 O O6    . DG A 19 ? 0.31727 0.29688 0.32624 -0.03522 0.03141  0.08614  19 DG A O6    
592 N N1    . DG A 19 ? 0.27542 0.30940 0.28233 -0.02155 0.02290  0.07784  19 DG A N1    
593 C C2    . DG A 19 ? 0.29601 0.36617 0.30162 -0.02025 0.01913  0.06606  19 DG A C2    
594 N N2    . DG A 19 ? 0.28514 0.36787 0.29382 -0.01107 0.01465  0.06354  19 DG A N2    
595 N N3    . DG A 19 ? 0.22247 0.31694 0.22781 -0.02733 0.01998  0.05411  19 DG A N3    
596 C C4    . DG A 19 ? 0.20593 0.28978 0.21035 -0.03855 0.02434  0.05761  19 DG A C4    
608 P P     . DC A 20 ? 0.25132 0.56322 0.29835 -0.03903 0.03386  -0.04042 20 DC A P     
609 O OP1   . DC A 20 ? 0.24808 0.58228 0.28312 -0.06076 0.04307  -0.02210 20 DC A OP1   
610 O OP2   . DC A 20 ? 0.27491 0.59880 0.30968 -0.03642 0.03298  -0.04451 20 DC A OP2   
611 O "O5'" . DC A 20 ? 0.24640 0.58336 0.32851 -0.02442 0.03156  -0.07511 20 DC A "O5'" 
612 C "C5'" . DC A 20 ? 0.21737 0.55205 0.31906 -0.00592 0.02572  -0.10271 20 DC A "C5'" 
613 C "C4'" . DC A 20 ? 0.28419 0.57995 0.41261 0.01242  0.01269  -0.10823 20 DC A "C4'" 
614 O "O4'" . DC A 20 ? 0.21285 0.53191 0.35987 0.01258  0.01220  -0.11024 20 DC A "O4'" 
615 C "C3'" . DC A 20 ? 0.29312 0.52731 0.40467 0.01188  0.00398  -0.08109 20 DC A "C3'" 
616 O "O3'" . DC A 20 ? 0.30576 0.51439 0.41715 0.01887  -0.00076 -0.08705 20 DC A "O3'" 
617 C "C2'" . DC A 20 ? 0.27232 0.48998 0.40331 0.02112  -0.00696 -0.07876 20 DC A "C2'" 
618 C "C1'" . DC A 20 ? 0.24895 0.52337 0.40003 0.01935  -0.00112 -0.09435 20 DC A "C1'" 
619 N N1    . DC A 20 ? 0.27675 0.56015 0.41471 0.00132  0.00303  -0.07664 20 DC A N1    
620 C C2    . DC A 20 ? 0.21474 0.48159 0.36004 0.00339  -0.00836 -0.06784 20 DC A C2    
621 O O2    . DC A 20 ? 0.32679 0.56963 0.48679 0.02097  -0.02288 -0.06926 20 DC A O2    
622 N N3    . DC A 20 ? 0.18120 0.45855 0.31623 -0.01618 -0.00394 -0.05700 20 DC A N3    
623 C C4    . DC A 20 ? 0.25181 0.54971 0.37184 -0.03697 0.01110  -0.05156 20 DC A C4    
624 N N4    . DC A 20 ? 0.31874 0.62056 0.43151 -0.05872 0.01521  -0.04162 20 DC A N4    
625 C C5    . DC A 20 ? 0.28036 0.59664 0.39124 -0.03869 0.02175  -0.05518 20 DC A C5    
626 C C6    . DC A 20 ? 0.28308 0.59523 0.40307 -0.01919 0.01733  -0.06989 20 DC A C6    
638 P P     . DG A 21 ? 0.30775 0.51749 0.28058 0.01321  -0.01099 0.01480  21 DG A P     
639 O OP1   . DG A 21 ? 0.32344 0.49048 0.28219 0.02543  -0.00646 -0.00699 21 DG A OP1   
640 O OP2   . DG A 21 ? 0.28408 0.50085 0.22892 -0.01399 -0.01585 0.01344  21 DG A OP2   
641 O "O5'" . DG A 21 ? 0.27565 0.49041 0.26990 0.01575  -0.01848 0.03219  21 DG A "O5'" 
642 C "C5'" . DG A 21 ? 0.24021 0.45160 0.26683 0.03966  -0.01365 0.04241  21 DG A "C5'" 
643 C "C4'" . DG A 21 ? 0.18803 0.36528 0.21642 0.04234  -0.01820 0.03974  21 DG A "C4'" 
644 O "O4'" . DG A 21 ? 0.21988 0.41642 0.24428 0.02250  -0.02844 0.05611  21 DG A "O4'" 
645 C "C3'" . DG A 21 ? 0.25750 0.39369 0.26091 0.03832  -0.01864 0.01393  21 DG A "C3'" 
646 O "O3'" . DG A 21 ? 0.27851 0.37447 0.28041 0.05451  -0.01431 0.00101  21 DG A "O3'" 
647 C "C2'" . DG A 21 ? 0.27321 0.40520 0.27877 0.02449  -0.02571 0.02132  21 DG A "C2'" 
648 C "C1'" . DG A 21 ? 0.24690 0.41510 0.25511 0.01374  -0.02851 0.04371  21 DG A "C1'" 
649 N N9    . DG A 21 ? 0.26498 0.44184 0.24122 -0.00717 -0.02624 0.03902  21 DG A N9    
650 C C8    . DG A 21 ? 0.27209 0.47179 0.22674 -0.02251 -0.02827 0.04207  21 DG A C8    
651 N N7    . DG A 21 ? 0.30702 0.49365 0.22373 -0.04125 -0.02207 0.03350  21 DG A N7    
652 C C5    . DG A 21 ? 0.28544 0.44824 0.20874 -0.03412 -0.01310 0.02848  21 DG A C5    
653 C C6    . DG A 21 ? 0.29952 0.44099 0.19912 -0.04219 0.00330  0.02173  21 DG A C6    
654 O O6    . DG A 21 ? 0.25849 0.38382 0.11739 -0.05671 0.01505  0.01352  21 DG A O6    
655 N N1    . DG A 21 ? 0.29644 0.42928 0.22794 -0.03084 0.00781  0.02596  21 DG A N1    
656 C C2    . DG A 21 ? 0.24249 0.37708 0.21251 -0.01865 -0.00568 0.03196  21 DG A C2    
657 N N2    . DG A 21 ? 0.28178 0.40751 0.27950 -0.01563 -0.00359 0.03768  21 DG A N2    
658 N N3    . DG A 21 ? 0.29402 0.43534 0.27506 -0.01033 -0.01802 0.03327  21 DG A N3    
659 C C4    . DG A 21 ? 0.20918 0.36876 0.17020 -0.01643 -0.01931 0.03317  21 DG A C4    
671 P P     . DT A 22 ? 0.31829 0.37682 0.28746 0.04894  -0.01824 -0.02453 22 DT A P     
672 O OP1   . DT A 22 ? 0.36725 0.37653 0.31935 0.06285  -0.01204 -0.03879 22 DT A OP1   
673 O OP2   . DT A 22 ? 0.28459 0.36852 0.23771 0.04342  -0.01350 -0.02919 22 DT A OP2   
674 O "O5'" . DT A 22 ? 0.32497 0.37908 0.30228 0.03136  -0.03248 -0.02076 22 DT A "O5'" 
675 C "C5'" . DT A 22 ? 0.26104 0.29510 0.25690 0.02888  -0.04021 -0.01248 22 DT A "C5'" 
676 C "C4'" . DT A 22 ? 0.25214 0.28881 0.26049 0.01226  -0.05082 -0.00725 22 DT A "C4'" 
677 O "O4'" . DT A 22 ? 0.29449 0.36733 0.30942 0.00729  -0.04080 0.00354  22 DT A "O4'" 
678 C "C3'" . DT A 22 ? 0.30122 0.32316 0.29453 0.00393  -0.06220 -0.01970 22 DT A "C3'" 
679 O "O3'" . DT A 22 ? 0.33674 0.34640 0.35056 -0.01048 -0.07903 -0.01125 22 DT A "O3'" 
680 C "C2'" . DT A 22 ? 0.29345 0.34769 0.28666 0.00305  -0.05229 -0.01701 22 DT A "C2'" 
681 C "C1'" . DT A 22 ? 0.31433 0.39232 0.32591 0.00175  -0.04009 -0.00161 22 DT A "C1'" 
682 N N1    . DT A 22 ? 0.25137 0.34898 0.24492 0.00118  -0.02448 -0.00283 22 DT A N1    
683 C C2    . DT A 22 ? 0.24285 0.34812 0.24051 -0.00396 -0.01069 0.00428  22 DT A C2    
684 O O2    . DT A 22 ? 0.24602 0.35268 0.27130 -0.00520 -0.00909 0.01514  22 DT A O2    
685 N N3    . DT A 22 ? 0.23142 0.34009 0.19905 -0.00849 0.00331  -0.00076 22 DT A N3    
686 C C4    . DT A 22 ? 0.27023 0.38525 0.21237 -0.01193 0.00053  -0.00754 22 DT A C4    
687 O O4    . DT A 22 ? 0.23687 0.35056 0.14876 -0.02277 0.01030  -0.01105 22 DT A O4    
688 C C5    . DT A 22 ? 0.26200 0.38154 0.21452 -0.00291 -0.01253 -0.00940 22 DT A C5    
689 C C7    . DT A 22 ? 0.29425 0.43129 0.23489 -0.00310 -0.01321 -0.01001 22 DT A C7    
690 C C6    . DT A 22 ? 0.26629 0.37165 0.23935 0.00459  -0.02179 -0.00908 22 DT A C6    
703 P P     . DC A 23 ? 0.37404 0.36515 0.37504 -0.02607 -0.10230 -0.01726 23 DC A P     
704 O OP1   . DC A 23 ? 0.44223 0.40607 0.45752 -0.04331 -0.12253 -0.01018 23 DC A OP1   
705 O OP2   . DC A 23 ? 0.40865 0.37920 0.36004 -0.01983 -0.10002 -0.03848 23 DC A OP2   
706 O "O5'" . DC A 23 ? 0.33658 0.37269 0.37180 -0.02814 -0.09844 0.00046  23 DC A "O5'" 
707 C "C5'" . DC A 23 ? 0.31506 0.37944 0.39836 -0.03082 -0.09116 0.02323  23 DC A "C5'" 
708 C "C4'" . DC A 23 ? 0.28445 0.38044 0.38914 -0.02366 -0.07457 0.03464  23 DC A "C4'" 
709 O "O4'" . DC A 23 ? 0.28651 0.38352 0.35937 -0.01110 -0.04992 0.02128  23 DC A "O4'" 
710 C "C3'" . DC A 23 ? 0.26793 0.36623 0.37204 -0.02775 -0.09126 0.03688  23 DC A "C3'" 
711 O "O3'" . DC A 23 ? 0.30799 0.43086 0.46793 -0.03814 -0.10631 0.06537  23 DC A "O3'" 
712 C "C2'" . DC A 23 ? 0.32758 0.43403 0.41675 -0.01237 -0.06462 0.03112  23 DC A "C2'" 
713 C "C1'" . DC A 23 ? 0.30429 0.41233 0.38365 -0.00527 -0.03726 0.02574  23 DC A "C1'" 
714 N N1    . DC A 23 ? 0.25574 0.35549 0.29207 0.00055  -0.02014 0.00861  23 DC A N1    
715 C C2    . DC A 23 ? 0.23941 0.33940 0.26956 0.00512  0.00812  0.01035  23 DC A C2    
716 O O2    . DC A 23 ? 0.23667 0.34407 0.29969 0.01004  0.02375  0.02601  23 DC A O2    
717 N N3    . DC A 23 ? 0.26351 0.35260 0.25108 0.00294  0.01881  -0.00428 23 DC A N3    
718 C C4    . DC A 23 ? 0.27178 0.36137 0.23560 -0.00029 0.00484  -0.01545 23 DC A C4    
719 N N4    . DC A 23 ? 0.28227 0.36854 0.21235 -0.00624 0.01336  -0.02433 23 DC A N4    
720 C C5    . DC A 23 ? 0.28762 0.37745 0.25972 0.00144  -0.01665 -0.01736 23 DC A C5    
721 C C6    . DC A 23 ? 0.25727 0.34648 0.25961 0.00015  -0.02917 -0.00747 23 DC A C6    
733 P P     . DC A 24 ? 0.34661 0.48123 0.51941 -0.04725 -0.13284 0.08040  24 DC A P     
734 O OP1   . DC A 24 ? 0.27339 0.43288 0.50615 -0.06320 -0.15220 0.11318  24 DC A OP1   
735 O OP2   . DC A 24 ? 0.32341 0.42040 0.42432 -0.05348 -0.14942 0.05271  24 DC A OP2   
736 O "O5'" . DC A 24 ? 0.34913 0.50804 0.54907 -0.02465 -0.10037 0.09314  24 DC A "O5'" 
737 C "C5'" . DC A 24 ? 0.36099 0.54694 0.61716 -0.01158 -0.06951 0.11511  24 DC A "C5'" 
738 C "C4'" . DC A 24 ? 0.29057 0.47720 0.55148 0.01084  -0.03437 0.11843  24 DC A "C4'" 
739 O "O4'" . DC A 24 ? 0.30510 0.45789 0.49700 0.01678  -0.01235 0.08410  24 DC A "O4'" 
740 C "C3'" . DC A 24 ? 0.31193 0.50508 0.58283 0.01141  -0.05417 0.13238  24 DC A "C3'" 
741 O "O3'" . DC A 24 ? 0.36851 0.59932 0.72242 0.02273  -0.04564 0.17473  24 DC A "O3'" 
742 C "C2'" . DC A 24 ? 0.38206 0.54155 0.59409 0.02346  -0.02999 0.10577  24 DC A "C2'" 
743 C "C1'" . DC A 24 ? 0.25851 0.39836 0.43566 0.02799  0.00239  0.08140  24 DC A "C1'" 
744 N N1    . DC A 24 ? 0.30624 0.41699 0.41117 0.02308  0.00406  0.04845  24 DC A N1    
745 C C2    . DC A 24 ? 0.32017 0.40678 0.39180 0.02973  0.03712  0.03491  24 DC A C2    
746 O O2    . DC A 24 ? 0.31881 0.39839 0.41297 0.04252  0.06916  0.04624  24 DC A O2    
747 N N3    . DC A 24 ? 0.32606 0.39548 0.34147 0.02091  0.03466  0.01121  24 DC A N3    
748 C C4    . DC A 24 ? 0.27372 0.35017 0.27060 0.01258  0.00788  0.00162  24 DC A C4    
749 N N4    . DC A 24 ? 0.33389 0.40210 0.28794 0.00634  0.00952  -0.01535 24 DC A N4    
750 C C5    . DC A 24 ? 0.26422 0.35339 0.28434 0.00881  -0.02033 0.01012  24 DC A C5    
751 C C6    . DC A 24 ? 0.28866 0.39429 0.36041 0.01096  -0.02483 0.03325  24 DC A C6    
763 P P     . DG A 25 ? 0.36548 0.60078 0.73258 0.02206  -0.06363 0.19708  25 DG A P     
764 O OP1   . DG A 25 ? 0.42701 0.68706 0.85494 0.01604  -0.06597 0.23446  25 DG A OP1   
765 O OP2   . DG A 25 ? 0.39585 0.61217 0.69893 0.00413  -0.10226 0.17621  25 DG A OP2   
766 O "O5'" . DG A 25 ? 0.25769 0.47994 0.63327 0.05475  -0.01726 0.19848  25 DG A "O5'" 
767 C "C5'" . DG A 25 ? 0.26898 0.48420 0.67099 0.07591  0.03442  0.20337  25 DG A "C5'" 
768 C "C4'" . DG A 25 ? 0.32066 0.49585 0.69505 0.10005  0.07783  0.18952  25 DG A "C4'" 
769 O "O4'" . DG A 25 ? 0.34232 0.47431 0.61924 0.08478  0.07413  0.14182  25 DG A "O4'" 
770 C "C3'" . DG A 25 ? 0.43963 0.61262 0.83284 0.10749  0.06767  0.21213  25 DG A "C3'" 
771 O "O3'" . DG A 25 ? 0.49630 0.63219 0.89439 0.13149  0.12178  0.21551  25 DG A "O3'" 
772 C "C2'" . DG A 25 ? 0.31084 0.45506 0.62129 0.08963  0.04023  0.17876  25 DG A "C2'" 
773 C "C1'" . DG A 25 ? 0.38466 0.48966 0.62822 0.08647  0.07076  0.13530  25 DG A "C1'" 
774 N N9    . DG A 25 ? 0.37343 0.45918 0.53840 0.06497  0.04856  0.09879  25 DG A N9    
775 C C8    . DG A 25 ? 0.35680 0.46065 0.50152 0.04531  0.00664  0.09044  25 DG A C8    
776 N N7    . DG A 25 ? 0.35784 0.44029 0.43752 0.03446  0.00393  0.05909  25 DG A N7    
777 C C5    . DG A 25 ? 0.33854 0.38973 0.39232 0.04159  0.04013  0.04626  25 DG A C5    
778 C C6    . DG A 25 ? 0.35016 0.37554 0.34249 0.03080  0.04989  0.01878  25 DG A C6    
779 O O6    . DG A 25 ? 0.33177 0.36351 0.28940 0.01811  0.03248  0.00292  25 DG A O6    
780 N N1    . DG A 25 ? 0.40209 0.39000 0.37610 0.03537  0.08511  0.01276  25 DG A N1    
781 C C2    . DG A 25 ? 0.37839 0.34976 0.38775 0.05454  0.11581  0.02906  25 DG A C2    
782 N N2    . DG A 25 ? 0.48288 0.40148 0.45322 0.05542  0.15243  0.01503  25 DG A N2    
783 N N3    . DG A 25 ? 0.39443 0.39737 0.47335 0.07073  0.11191  0.05900  25 DG A N3    
784 C C4    . DG A 25 ? 0.37674 0.42175 0.47478 0.06021  0.06963  0.06682  25 DG A C4    
796 P P     . DC A 26 ? 0.64584 0.78151 1.08490 0.14300  0.12718  0.24942  26 DC A P     
797 O OP1   . DC A 26 ? 0.69730 0.81428 1.16717 0.16270  0.18070  0.26519  26 DC A OP1   
798 O OP2   . DC A 26 ? 0.53099 0.72047 1.00742 0.12091  0.06887  0.27897  26 DC A OP2   
799 O "O5'" . DC A 26 ? 0.58509 0.66305 0.96238 0.15271  0.14281  0.22292  26 DC A "O5'" 
800 C "C5'" . DC A 26 ? 0.48739 0.49964 0.80086 0.16117  0.19200  0.18418  26 DC A "C5'" 
801 C "C4'" . DC A 26 ? 0.63396 0.59571 0.86778 0.14825  0.18529  0.15337  26 DC A "C4'" 
802 O "O4'" . DC A 26 ? 0.64911 0.62907 0.82482 0.11621  0.14451  0.12296  26 DC A "O4'" 
803 C "C3'" . DC A 26 ? 0.64612 0.61288 0.90155 0.15107  0.16038  0.18172  26 DC A "C3'" 
804 O "O3'" . DC A 26 ? 0.71090 0.62048 0.97125 0.17347  0.20495  0.19052  26 DC A "O3'" 
805 C "C2'" . DC A 26 ? 0.55190 0.51215 0.72658 0.11815  0.12278  0.14988  26 DC A "C2'" 
806 C "C1'" . DC A 26 ? 0.51897 0.47597 0.64250 0.10099  0.12611  0.10976  26 DC A "C1'" 
807 N N1    . DC A 26 ? 0.39215 0.38323 0.48460 0.07640  0.08020  0.09612  26 DC A N1    
808 C C2    . DC A 26 ? 0.39971 0.36987 0.42146 0.05634  0.07664  0.06242  26 DC A C2    
809 O O2    . DC A 26 ? 0.48967 0.41444 0.47243 0.05331  0.10590  0.04403  26 DC A O2    
810 N N3    . DC A 26 ? 0.39888 0.39679 0.39661 0.03988  0.04263  0.05218  26 DC A N3    
811 C C4    . DC A 26 ? 0.36745 0.40133 0.39566 0.03869  0.01103  0.06946  26 DC A C4    
812 N N4    . DC A 26 ? 0.36450 0.41072 0.35750 0.02350  -0.01574 0.05496  26 DC A N4    
813 C C5    . DC A 26 ? 0.39298 0.45002 0.48947 0.05186  0.00640  0.10437  26 DC A C5    
814 C C6    . DC A 26 ? 0.37431 0.41425 0.50756 0.07264  0.04241  0.11919  26 DC A C6    
826 P P     . DC A 27 ? 0.82511 0.72177 1.08660 0.17273  0.18538  0.21334  27 DC A P     
827 O OP1   . DC A 27 ? 0.79600 0.68069 1.10277 0.19202  0.22172  0.23461  27 DC A OP1   
828 O OP2   . DC A 27 ? 0.52115 0.48106 0.79844 0.15458  0.12159  0.23699  27 DC A OP2   
829 O "O5'" . DC A 27 ? 0.75841 0.58231 0.91570 0.15059  0.19747  0.16648  27 DC A "O5'" 
830 C "C5'" . DC A 27 ? 0.63000 0.40703 0.72101 0.13911  0.22877  0.12023  27 DC A "C5'" 
831 C "C4'" . DC A 27 ? 0.67009 0.40951 0.67349 0.10537  0.21608  0.08580  27 DC A "C4'" 
832 O "O4'" . DC A 27 ? 0.59654 0.39573 0.57968 0.08001  0.16909  0.07354  27 DC A "O4'" 
833 C "C3'" . DC A 27 ? 0.69306 0.40225 0.69312 0.10458  0.21132  0.10440  27 DC A "C3'" 
834 O "O3'" . DC A 27 ? 0.84742 0.47832 0.77442 0.08507  0.23578  0.07422  27 DC A "O3'" 
835 C "C2'" . DC A 27 ? 0.62891 0.40389 0.62687 0.08451  0.15618  0.11398  27 DC A "C2'" 
836 C "C1'" . DC A 27 ? 0.55004 0.35867 0.51383 0.06441  0.13977  0.08113  27 DC A "C1'" 
837 N N1    . DC A 27 ? 0.46118 0.33998 0.44304 0.05742  0.09481  0.09126  27 DC A N1    
838 C C2    . DC A 27 ? 0.43580 0.33462 0.36846 0.03282  0.07097  0.06902  27 DC A C2    
839 O O2    . DC A 27 ? 0.43175 0.30173 0.31658 0.01540  0.08281  0.04673  27 DC A O2    
840 N N3    . DC A 27 ? 0.42087 0.36807 0.35955 0.02772  0.03639  0.07412  27 DC A N3    
841 C C4    . DC A 27 ? 0.37823 0.35519 0.36717 0.03959  0.01893  0.10050  27 DC A C4    
842 N N4    . DC A 27 ? 0.36400 0.37569 0.34471 0.02841  -0.01635 0.10161  27 DC A N4    
843 C C5    . DC A 27 ? 0.39727 0.36784 0.44810 0.06272  0.03817  0.12905  27 DC A C5    
844 C C6    . DC A 27 ? 0.47209 0.39227 0.51818 0.07418  0.07928  0.12298  27 DC A C6    
856 P P     . DG A 28 ? 0.88474 0.44660 0.80528 0.09010  0.25503  0.09097  28 DG A P     
857 O OP1   . DG A 28 ? 1.02734 0.49602 0.87548 0.07495  0.29501  0.05367  28 DG A OP1   
858 O OP2   . DG A 28 ? 0.84625 0.43284 0.85401 0.12751  0.25854  0.14029  28 DG A OP2   
859 O "O5'" . DG A 28 ? 0.75602 0.35087 0.64326 0.05643  0.21052  0.09082  28 DG A "O5'" 
860 C "C5'" . DG A 28 ? 0.75944 0.36118 0.58373 0.01954  0.19541  0.05553  28 DG A "C5'" 
861 C "C4'" . DG A 28 ? 0.65093 0.29969 0.46532 -0.00187 0.15777  0.06639  28 DG A "C4'" 
862 O "O4'" . DG A 28 ? 0.65712 0.38862 0.50389 0.00653  0.12518  0.07663  28 DG A "O4'" 
863 C "C3'" . DG A 28 ? 0.75206 0.37706 0.58362 0.00505  0.15731  0.10048  28 DG A "C3'" 
864 O "O3'" . DG A 28 ? 0.77113 0.38857 0.55753 -0.02871 0.14524  0.09499  28 DG A "O3'" 
865 C "C2'" . DG A 28 ? 0.66774 0.36508 0.55312 0.02554  0.12714  0.13420  28 DG A "C2'" 
866 C "C1'" . DG A 28 ? 0.61116 0.36970 0.47778 0.01076  0.10236  0.10932  28 DG A "C1'" 
867 N N9    . DG A 28 ? 0.51788 0.33808 0.42548 0.02582  0.07549  0.12704  28 DG A N9    
868 C C8    . DG A 28 ? 0.54808 0.38252 0.51935 0.05256  0.07477  0.15877  28 DG A C8    
869 N N7    . DG A 28 ? 0.48065 0.37348 0.47224 0.05191  0.04114  0.16933  28 DG A N7    
870 C C5    . DG A 28 ? 0.45859 0.36891 0.39218 0.02756  0.02408  0.13996  28 DG A C5    
871 C C6    . DG A 28 ? 0.45939 0.41354 0.37507 0.01625  -0.00780 0.13233  28 DG A C6    
872 O O6    . DG A 28 ? 0.46217 0.44886 0.40493 0.01931  -0.03417 0.14934  28 DG A O6    
873 N N1    . DG A 28 ? 0.44819 0.40362 0.30902 -0.00158 -0.00675 0.10332  28 DG A N1    
874 C C2    . DG A 28 ? 0.49011 0.41840 0.32269 -0.01223 0.01578  0.08780  28 DG A C2    
875 N N2    . DG A 28 ? 0.50607 0.45200 0.30045 -0.02786 0.01333  0.06805  28 DG A N2    
876 N N3    . DG A 28 ? 0.48792 0.37256 0.32952 -0.00893 0.03965  0.09310  28 DG A N3    
877 C C4    . DG A 28 ? 0.50569 0.37883 0.39511 0.01317  0.04527  0.11708  28 DG A C4    
889 P P     . DC A 29 ? 0.81535 0.38416 0.59956 -0.03272 0.15184  0.12426  29 DC A P     
890 O OP1   . DC A 29 ? 0.90376 0.37158 0.65249 -0.04398 0.18727  0.10623  29 DC A OP1   
891 O OP2   . DC A 29 ? 0.89092 0.49075 0.73261 -0.00061 0.14034  0.16755  29 DC A OP2   
892 O "O5'" . DC A 29 ? 0.87014 0.48355 0.62164 -0.06712 0.12496  0.12592  29 DC A "O5'" 
893 C "C5'" . DC A 29 ? 0.81081 0.48729 0.54431 -0.08445 0.10675  0.10251  29 DC A "C5'" 
894 C "C4'" . DC A 29 ? 0.78556 0.53622 0.53013 -0.07728 0.07964  0.12108  29 DC A "C4'" 
895 O "O4'" . DC A 29 ? 0.70803 0.48989 0.48525 -0.04969 0.06911  0.12383  29 DC A "O4'" 
896 C "C3'" . DC A 29 ? 0.67286 0.42043 0.41996 -0.07556 0.07136  0.15931  29 DC A "C3'" 
897 O "O3'" . DC A 29 ? 0.67758 0.42579 0.39269 -0.10563 0.07270  0.16334  29 DC A "O3'" 
898 C "C2'" . DC A 29 ? 0.64330 0.45207 0.40022 -0.06024 0.04472  0.17195  29 DC A "C2'" 
899 C "C1'" . DC A 29 ? 0.61125 0.44108 0.38543 -0.04771 0.04380  0.14358  29 DC A "C1'" 
900 N N1    . DC A 29 ? 0.58227 0.43241 0.39686 -0.02304 0.02798  0.16238  29 DC A N1    
901 C C2    . DC A 29 ? 0.56733 0.46703 0.37425 -0.02309 0.00195  0.15746  29 DC A C2    
902 O O2    . DC A 29 ? 0.65134 0.57308 0.41850 -0.03759 -0.00168 0.13628  29 DC A O2    
903 N N3    . DC A 29 ? 0.54202 0.46238 0.38695 -0.00809 -0.01763 0.17809  29 DC A N3    
904 C C4    . DC A 29 ? 0.52673 0.42910 0.42666 0.01180  -0.00888 0.20648  29 DC A C4    
905 N N4    . DC A 29 ? 0.51712 0.45253 0.46555 0.02454  -0.03148 0.23360  29 DC A N4    
906 C C5    . DC A 29 ? 0.56342 0.41069 0.47276 0.01882  0.02438  0.21067  29 DC A C5    
907 C C6    . DC A 29 ? 0.57726 0.39580 0.43752 -0.00171 0.04008  0.18622  29 DC A C6    
# 
