data_8JZQ
# 
_entry.id   8JZQ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8JZQ         pdb_00008jzq 10.2210/pdb8jzq/pdb 
WWPDB D_1300039211 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-29 ? 
2 'Structure model' 1 1 2025-02-12 ? 
3 'Structure model' 1 2 2025-04-02 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 3 'Structure model' citation        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.page_first'              
2 2 'Structure model' '_citation.page_last'               
3 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
4 2 'Structure model' '_citation.title'                   
5 3 'Structure model' '_citation.journal_volume'          
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8JZQ 
_pdbx_database_status.recvd_initial_deposition_date   2023-07-06 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 qiushuang_ji@tju.edu.cn Qiushuang Ji  ? 'principal investigator/group leader' 0000-0002-1938-1187 
3 liuyirong@tju.edu.cn    Yirong    Liu ? 'principal investigator/group leader' 0000-0002-3199-3928 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Mei, K.' 1 ? 
'Ji, Q.'  2 ? 
'Liu, Y.' 3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   DE 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Adv Sci' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2198-3844 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            12 
_citation.language                  ? 
_citation.page_first                e2413185 
_citation.page_last                 e2413185 
_citation.title                     
'Structural Insights into the Substrate Recognition of Ginsenoside Glycosyltransferase Pq3-O-UGT2.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1002/advs.202413185 
_citation.pdbx_database_id_PubMed   39887940 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ji, Q.'    1  0000-0002-1938-1187 
primary 'Liu, Y.'   2  ?                   
primary 'Zhang, H.' 3  ?                   
primary 'Gao, Y.'   4  ?                   
primary 'Ding, Y.'  5  ?                   
primary 'Ding, Y.'  6  ?                   
primary 'Xie, J.'   7  ?                   
primary 'Zhang, J.' 8  ?                   
primary 'Jin, X.'   9  ?                   
primary 'Lai, B.'   10 ?                   
primary 'Chen, C.'  11 ?                   
primary 'Wang, J.'  12 ?                   
primary 'Gao, W.'   13 ?                   
primary 'Mei, K.'   14 0000-0001-7827-2944 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           Glycosyltransferase 
_entity.formula_weight             50888.051 
_entity.pdbx_number_of_molecules   4 
_entity.pdbx_ec                    2.4.1.- 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDNQKGRISIALLPFLAHGHISPFFELAKQLAKRNCNVFLCSTPINLSSIKDKDSSASIKLVELHLPSSPDLPPHYHTTN
GLPSHLMLPLRNAFETAGPTFSEILKTLNPDLLIYDFNPSWAPEIASSHNIPAVYFLTTAAASSSIGLHAFKNPGEKYPF
PDFYDNSNIIPEPPSADNMKLLHDFIACFERSCDIILIKSFRELEGKYIDLLSTLSDKTLVPVGPLVQDPMGHNEDPKTE
QIINWLDKRAESTVVFVCFGSEYFLSNEELEEVAIGLEISTVNFIWAVRLIEGEKKGILPEGFVQRVGDRGLVVEGWAPQ
ARILGHSSTGGFVSHCGWSSIAESMKFGVPVIAMARHLDQPLNGKLAAEVGVGMEVVRDENGKYKREGIAEVIRKVVVEK
SGEVIRRKARELSEKMKEKGEQEIDRAVEELVQICKKKKDEQENLYFQGHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDNQKGRISIALLPFLAHGHISPFFELAKQLAKRNCNVFLCSTPINLSSIKDKDSSASIKLVELHLPSSPDLPPHYHTTN
GLPSHLMLPLRNAFETAGPTFSEILKTLNPDLLIYDFNPSWAPEIASSHNIPAVYFLTTAAASSSIGLHAFKNPGEKYPF
PDFYDNSNIIPEPPSADNMKLLHDFIACFERSCDIILIKSFRELEGKYIDLLSTLSDKTLVPVGPLVQDPMGHNEDPKTE
QIINWLDKRAESTVVFVCFGSEYFLSNEELEEVAIGLEISTVNFIWAVRLIEGEKKGILPEGFVQRVGDRGLVVEGWAPQ
ARILGHSSTGGFVSHCGWSSIAESMKFGVPVIAMARHLDQPLNGKLAAEVGVGMEVVRDENGKYKREGIAEVIRKVVVEK
SGEVIRRKARELSEKMKEKGEQEIDRAVEELVQICKKKKDEQENLYFQGHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   ASN n 
1 4   GLN n 
1 5   LYS n 
1 6   GLY n 
1 7   ARG n 
1 8   ILE n 
1 9   SER n 
1 10  ILE n 
1 11  ALA n 
1 12  LEU n 
1 13  LEU n 
1 14  PRO n 
1 15  PHE n 
1 16  LEU n 
1 17  ALA n 
1 18  HIS n 
1 19  GLY n 
1 20  HIS n 
1 21  ILE n 
1 22  SER n 
1 23  PRO n 
1 24  PHE n 
1 25  PHE n 
1 26  GLU n 
1 27  LEU n 
1 28  ALA n 
1 29  LYS n 
1 30  GLN n 
1 31  LEU n 
1 32  ALA n 
1 33  LYS n 
1 34  ARG n 
1 35  ASN n 
1 36  CYS n 
1 37  ASN n 
1 38  VAL n 
1 39  PHE n 
1 40  LEU n 
1 41  CYS n 
1 42  SER n 
1 43  THR n 
1 44  PRO n 
1 45  ILE n 
1 46  ASN n 
1 47  LEU n 
1 48  SER n 
1 49  SER n 
1 50  ILE n 
1 51  LYS n 
1 52  ASP n 
1 53  LYS n 
1 54  ASP n 
1 55  SER n 
1 56  SER n 
1 57  ALA n 
1 58  SER n 
1 59  ILE n 
1 60  LYS n 
1 61  LEU n 
1 62  VAL n 
1 63  GLU n 
1 64  LEU n 
1 65  HIS n 
1 66  LEU n 
1 67  PRO n 
1 68  SER n 
1 69  SER n 
1 70  PRO n 
1 71  ASP n 
1 72  LEU n 
1 73  PRO n 
1 74  PRO n 
1 75  HIS n 
1 76  TYR n 
1 77  HIS n 
1 78  THR n 
1 79  THR n 
1 80  ASN n 
1 81  GLY n 
1 82  LEU n 
1 83  PRO n 
1 84  SER n 
1 85  HIS n 
1 86  LEU n 
1 87  MET n 
1 88  LEU n 
1 89  PRO n 
1 90  LEU n 
1 91  ARG n 
1 92  ASN n 
1 93  ALA n 
1 94  PHE n 
1 95  GLU n 
1 96  THR n 
1 97  ALA n 
1 98  GLY n 
1 99  PRO n 
1 100 THR n 
1 101 PHE n 
1 102 SER n 
1 103 GLU n 
1 104 ILE n 
1 105 LEU n 
1 106 LYS n 
1 107 THR n 
1 108 LEU n 
1 109 ASN n 
1 110 PRO n 
1 111 ASP n 
1 112 LEU n 
1 113 LEU n 
1 114 ILE n 
1 115 TYR n 
1 116 ASP n 
1 117 PHE n 
1 118 ASN n 
1 119 PRO n 
1 120 SER n 
1 121 TRP n 
1 122 ALA n 
1 123 PRO n 
1 124 GLU n 
1 125 ILE n 
1 126 ALA n 
1 127 SER n 
1 128 SER n 
1 129 HIS n 
1 130 ASN n 
1 131 ILE n 
1 132 PRO n 
1 133 ALA n 
1 134 VAL n 
1 135 TYR n 
1 136 PHE n 
1 137 LEU n 
1 138 THR n 
1 139 THR n 
1 140 ALA n 
1 141 ALA n 
1 142 ALA n 
1 143 SER n 
1 144 SER n 
1 145 SER n 
1 146 ILE n 
1 147 GLY n 
1 148 LEU n 
1 149 HIS n 
1 150 ALA n 
1 151 PHE n 
1 152 LYS n 
1 153 ASN n 
1 154 PRO n 
1 155 GLY n 
1 156 GLU n 
1 157 LYS n 
1 158 TYR n 
1 159 PRO n 
1 160 PHE n 
1 161 PRO n 
1 162 ASP n 
1 163 PHE n 
1 164 TYR n 
1 165 ASP n 
1 166 ASN n 
1 167 SER n 
1 168 ASN n 
1 169 ILE n 
1 170 ILE n 
1 171 PRO n 
1 172 GLU n 
1 173 PRO n 
1 174 PRO n 
1 175 SER n 
1 176 ALA n 
1 177 ASP n 
1 178 ASN n 
1 179 MET n 
1 180 LYS n 
1 181 LEU n 
1 182 LEU n 
1 183 HIS n 
1 184 ASP n 
1 185 PHE n 
1 186 ILE n 
1 187 ALA n 
1 188 CYS n 
1 189 PHE n 
1 190 GLU n 
1 191 ARG n 
1 192 SER n 
1 193 CYS n 
1 194 ASP n 
1 195 ILE n 
1 196 ILE n 
1 197 LEU n 
1 198 ILE n 
1 199 LYS n 
1 200 SER n 
1 201 PHE n 
1 202 ARG n 
1 203 GLU n 
1 204 LEU n 
1 205 GLU n 
1 206 GLY n 
1 207 LYS n 
1 208 TYR n 
1 209 ILE n 
1 210 ASP n 
1 211 LEU n 
1 212 LEU n 
1 213 SER n 
1 214 THR n 
1 215 LEU n 
1 216 SER n 
1 217 ASP n 
1 218 LYS n 
1 219 THR n 
1 220 LEU n 
1 221 VAL n 
1 222 PRO n 
1 223 VAL n 
1 224 GLY n 
1 225 PRO n 
1 226 LEU n 
1 227 VAL n 
1 228 GLN n 
1 229 ASP n 
1 230 PRO n 
1 231 MET n 
1 232 GLY n 
1 233 HIS n 
1 234 ASN n 
1 235 GLU n 
1 236 ASP n 
1 237 PRO n 
1 238 LYS n 
1 239 THR n 
1 240 GLU n 
1 241 GLN n 
1 242 ILE n 
1 243 ILE n 
1 244 ASN n 
1 245 TRP n 
1 246 LEU n 
1 247 ASP n 
1 248 LYS n 
1 249 ARG n 
1 250 ALA n 
1 251 GLU n 
1 252 SER n 
1 253 THR n 
1 254 VAL n 
1 255 VAL n 
1 256 PHE n 
1 257 VAL n 
1 258 CYS n 
1 259 PHE n 
1 260 GLY n 
1 261 SER n 
1 262 GLU n 
1 263 TYR n 
1 264 PHE n 
1 265 LEU n 
1 266 SER n 
1 267 ASN n 
1 268 GLU n 
1 269 GLU n 
1 270 LEU n 
1 271 GLU n 
1 272 GLU n 
1 273 VAL n 
1 274 ALA n 
1 275 ILE n 
1 276 GLY n 
1 277 LEU n 
1 278 GLU n 
1 279 ILE n 
1 280 SER n 
1 281 THR n 
1 282 VAL n 
1 283 ASN n 
1 284 PHE n 
1 285 ILE n 
1 286 TRP n 
1 287 ALA n 
1 288 VAL n 
1 289 ARG n 
1 290 LEU n 
1 291 ILE n 
1 292 GLU n 
1 293 GLY n 
1 294 GLU n 
1 295 LYS n 
1 296 LYS n 
1 297 GLY n 
1 298 ILE n 
1 299 LEU n 
1 300 PRO n 
1 301 GLU n 
1 302 GLY n 
1 303 PHE n 
1 304 VAL n 
1 305 GLN n 
1 306 ARG n 
1 307 VAL n 
1 308 GLY n 
1 309 ASP n 
1 310 ARG n 
1 311 GLY n 
1 312 LEU n 
1 313 VAL n 
1 314 VAL n 
1 315 GLU n 
1 316 GLY n 
1 317 TRP n 
1 318 ALA n 
1 319 PRO n 
1 320 GLN n 
1 321 ALA n 
1 322 ARG n 
1 323 ILE n 
1 324 LEU n 
1 325 GLY n 
1 326 HIS n 
1 327 SER n 
1 328 SER n 
1 329 THR n 
1 330 GLY n 
1 331 GLY n 
1 332 PHE n 
1 333 VAL n 
1 334 SER n 
1 335 HIS n 
1 336 CYS n 
1 337 GLY n 
1 338 TRP n 
1 339 SER n 
1 340 SER n 
1 341 ILE n 
1 342 ALA n 
1 343 GLU n 
1 344 SER n 
1 345 MET n 
1 346 LYS n 
1 347 PHE n 
1 348 GLY n 
1 349 VAL n 
1 350 PRO n 
1 351 VAL n 
1 352 ILE n 
1 353 ALA n 
1 354 MET n 
1 355 ALA n 
1 356 ARG n 
1 357 HIS n 
1 358 LEU n 
1 359 ASP n 
1 360 GLN n 
1 361 PRO n 
1 362 LEU n 
1 363 ASN n 
1 364 GLY n 
1 365 LYS n 
1 366 LEU n 
1 367 ALA n 
1 368 ALA n 
1 369 GLU n 
1 370 VAL n 
1 371 GLY n 
1 372 VAL n 
1 373 GLY n 
1 374 MET n 
1 375 GLU n 
1 376 VAL n 
1 377 VAL n 
1 378 ARG n 
1 379 ASP n 
1 380 GLU n 
1 381 ASN n 
1 382 GLY n 
1 383 LYS n 
1 384 TYR n 
1 385 LYS n 
1 386 ARG n 
1 387 GLU n 
1 388 GLY n 
1 389 ILE n 
1 390 ALA n 
1 391 GLU n 
1 392 VAL n 
1 393 ILE n 
1 394 ARG n 
1 395 LYS n 
1 396 VAL n 
1 397 VAL n 
1 398 VAL n 
1 399 GLU n 
1 400 LYS n 
1 401 SER n 
1 402 GLY n 
1 403 GLU n 
1 404 VAL n 
1 405 ILE n 
1 406 ARG n 
1 407 ARG n 
1 408 LYS n 
1 409 ALA n 
1 410 ARG n 
1 411 GLU n 
1 412 LEU n 
1 413 SER n 
1 414 GLU n 
1 415 LYS n 
1 416 MET n 
1 417 LYS n 
1 418 GLU n 
1 419 LYS n 
1 420 GLY n 
1 421 GLU n 
1 422 GLN n 
1 423 GLU n 
1 424 ILE n 
1 425 ASP n 
1 426 ARG n 
1 427 ALA n 
1 428 VAL n 
1 429 GLU n 
1 430 GLU n 
1 431 LEU n 
1 432 VAL n 
1 433 GLN n 
1 434 ILE n 
1 435 CYS n 
1 436 LYS n 
1 437 LYS n 
1 438 LYS n 
1 439 LYS n 
1 440 ASP n 
1 441 GLU n 
1 442 GLN n 
1 443 GLU n 
1 444 ASN n 
1 445 LEU n 
1 446 TYR n 
1 447 PHE n 
1 448 GLN n 
1 449 GLY n 
1 450 HIS n 
1 451 HIS n 
1 452 HIS n 
1 453 HIS n 
1 454 HIS n 
1 455 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   455 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Panax quinquefolius' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     44588 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ASP 2   2   ?   ?   ?   A . n 
A 1 3   ASN 3   3   ?   ?   ?   A . n 
A 1 4   GLN 4   4   ?   ?   ?   A . n 
A 1 5   LYS 5   5   ?   ?   ?   A . n 
A 1 6   GLY 6   6   ?   ?   ?   A . n 
A 1 7   ARG 7   7   ?   ?   ?   A . n 
A 1 8   ILE 8   8   8   ILE ILE A . n 
A 1 9   SER 9   9   9   SER SER A . n 
A 1 10  ILE 10  10  10  ILE ILE A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  LEU 12  12  12  LEU LEU A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  PRO 14  14  14  PRO PRO A . n 
A 1 15  PHE 15  15  15  PHE PHE A . n 
A 1 16  LEU 16  16  16  LEU LEU A . n 
A 1 17  ALA 17  17  17  ALA ALA A . n 
A 1 18  HIS 18  18  18  HIS HIS A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  HIS 20  20  20  HIS HIS A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  SER 22  22  22  SER SER A . n 
A 1 23  PRO 23  23  23  PRO PRO A . n 
A 1 24  PHE 24  24  24  PHE PHE A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  ALA 28  28  28  ALA ALA A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  GLN 30  30  30  GLN GLN A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  ALA 32  32  32  ALA ALA A . n 
A 1 33  LYS 33  33  33  LYS LYS A . n 
A 1 34  ARG 34  34  34  ARG ARG A . n 
A 1 35  ASN 35  35  35  ASN ASN A . n 
A 1 36  CYS 36  36  36  CYS CYS A . n 
A 1 37  ASN 37  37  37  ASN ASN A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  PHE 39  39  39  PHE PHE A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  CYS 41  41  41  CYS CYS A . n 
A 1 42  SER 42  42  42  SER SER A . n 
A 1 43  THR 43  43  43  THR THR A . n 
A 1 44  PRO 44  44  44  PRO PRO A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  ASN 46  46  46  ASN ASN A . n 
A 1 47  LEU 47  47  47  LEU LEU A . n 
A 1 48  SER 48  48  48  SER SER A . n 
A 1 49  SER 49  49  49  SER SER A . n 
A 1 50  ILE 50  50  50  ILE ILE A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  LYS 53  53  53  LYS LYS A . n 
A 1 54  ASP 54  54  54  ASP ASP A . n 
A 1 55  SER 55  55  55  SER SER A . n 
A 1 56  SER 56  56  56  SER SER A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  SER 58  58  58  SER SER A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  LYS 60  60  60  LYS LYS A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  VAL 62  62  62  VAL VAL A . n 
A 1 63  GLU 63  63  63  GLU GLU A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  HIS 65  65  65  HIS HIS A . n 
A 1 66  LEU 66  66  ?   ?   ?   A . n 
A 1 67  PRO 67  67  ?   ?   ?   A . n 
A 1 68  SER 68  68  ?   ?   ?   A . n 
A 1 69  SER 69  69  ?   ?   ?   A . n 
A 1 70  PRO 70  70  ?   ?   ?   A . n 
A 1 71  ASP 71  71  ?   ?   ?   A . n 
A 1 72  LEU 72  72  ?   ?   ?   A . n 
A 1 73  PRO 73  73  ?   ?   ?   A . n 
A 1 74  PRO 74  74  ?   ?   ?   A . n 
A 1 75  HIS 75  75  ?   ?   ?   A . n 
A 1 76  TYR 76  76  ?   ?   ?   A . n 
A 1 77  HIS 77  77  ?   ?   ?   A . n 
A 1 78  THR 78  78  ?   ?   ?   A . n 
A 1 79  THR 79  79  ?   ?   ?   A . n 
A 1 80  ASN 80  80  ?   ?   ?   A . n 
A 1 81  GLY 81  81  ?   ?   ?   A . n 
A 1 82  LEU 82  82  ?   ?   ?   A . n 
A 1 83  PRO 83  83  ?   ?   ?   A . n 
A 1 84  SER 84  84  ?   ?   ?   A . n 
A 1 85  HIS 85  85  ?   ?   ?   A . n 
A 1 86  LEU 86  86  ?   ?   ?   A . n 
A 1 87  MET 87  87  ?   ?   ?   A . n 
A 1 88  LEU 88  88  ?   ?   ?   A . n 
A 1 89  PRO 89  89  ?   ?   ?   A . n 
A 1 90  LEU 90  90  ?   ?   ?   A . n 
A 1 91  ARG 91  91  91  ARG ARG A . n 
A 1 92  ASN 92  92  92  ASN ASN A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  PHE 94  94  94  PHE PHE A . n 
A 1 95  GLU 95  95  95  GLU GLU A . n 
A 1 96  THR 96  96  96  THR THR A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  GLY 98  98  98  GLY GLY A . n 
A 1 99  PRO 99  99  99  PRO PRO A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 SER 102 102 102 SER SER A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 ILE 104 104 104 ILE ILE A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 THR 107 107 107 THR THR A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 ASN 109 109 109 ASN ASN A . n 
A 1 110 PRO 110 110 110 PRO PRO A . n 
A 1 111 ASP 111 111 111 ASP ASP A . n 
A 1 112 LEU 112 112 112 LEU LEU A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 ILE 114 114 114 ILE ILE A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 ASP 116 116 116 ASP ASP A . n 
A 1 117 PHE 117 117 117 PHE PHE A . n 
A 1 118 ASN 118 118 118 ASN ASN A . n 
A 1 119 PRO 119 119 119 PRO PRO A . n 
A 1 120 SER 120 120 120 SER SER A . n 
A 1 121 TRP 121 121 121 TRP TRP A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 PRO 123 123 123 PRO PRO A . n 
A 1 124 GLU 124 124 124 GLU GLU A . n 
A 1 125 ILE 125 125 125 ILE ILE A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 SER 127 127 127 SER SER A . n 
A 1 128 SER 128 128 128 SER SER A . n 
A 1 129 HIS 129 129 129 HIS HIS A . n 
A 1 130 ASN 130 130 130 ASN ASN A . n 
A 1 131 ILE 131 131 131 ILE ILE A . n 
A 1 132 PRO 132 132 132 PRO PRO A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 TYR 135 135 135 TYR TYR A . n 
A 1 136 PHE 136 136 136 PHE PHE A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 THR 138 138 138 THR THR A . n 
A 1 139 THR 139 139 139 THR THR A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 ALA 141 141 141 ALA ALA A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 SER 143 143 143 SER SER A . n 
A 1 144 SER 144 144 144 SER SER A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 HIS 149 149 149 HIS HIS A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 PHE 151 151 151 PHE PHE A . n 
A 1 152 LYS 152 152 152 LYS LYS A . n 
A 1 153 ASN 153 153 153 ASN ASN A . n 
A 1 154 PRO 154 154 154 PRO PRO A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 GLU 156 156 156 GLU GLU A . n 
A 1 157 LYS 157 157 157 LYS LYS A . n 
A 1 158 TYR 158 158 158 TYR TYR A . n 
A 1 159 PRO 159 159 159 PRO PRO A . n 
A 1 160 PHE 160 160 160 PHE PHE A . n 
A 1 161 PRO 161 161 161 PRO PRO A . n 
A 1 162 ASP 162 162 162 ASP ASP A . n 
A 1 163 PHE 163 163 163 PHE PHE A . n 
A 1 164 TYR 164 164 164 TYR TYR A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 ASN 166 166 166 ASN ASN A . n 
A 1 167 SER 167 167 167 SER SER A . n 
A 1 168 ASN 168 168 ?   ?   ?   A . n 
A 1 169 ILE 169 169 ?   ?   ?   A . n 
A 1 170 ILE 170 170 ?   ?   ?   A . n 
A 1 171 PRO 171 171 ?   ?   ?   A . n 
A 1 172 GLU 172 172 ?   ?   ?   A . n 
A 1 173 PRO 173 173 ?   ?   ?   A . n 
A 1 174 PRO 174 174 ?   ?   ?   A . n 
A 1 175 SER 175 175 ?   ?   ?   A . n 
A 1 176 ALA 176 176 ?   ?   ?   A . n 
A 1 177 ASP 177 177 ?   ?   ?   A . n 
A 1 178 ASN 178 178 178 ASN ASN A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 LYS 180 180 180 LYS LYS A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 ASP 184 184 184 ASP ASP A . n 
A 1 185 PHE 185 185 185 PHE PHE A . n 
A 1 186 ILE 186 186 186 ILE ILE A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 CYS 188 188 188 CYS CYS A . n 
A 1 189 PHE 189 189 189 PHE PHE A . n 
A 1 190 GLU 190 190 190 GLU GLU A . n 
A 1 191 ARG 191 191 191 ARG ARG A . n 
A 1 192 SER 192 192 192 SER SER A . n 
A 1 193 CYS 193 193 193 CYS CYS A . n 
A 1 194 ASP 194 194 194 ASP ASP A . n 
A 1 195 ILE 195 195 195 ILE ILE A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 ILE 198 198 198 ILE ILE A . n 
A 1 199 LYS 199 199 199 LYS LYS A . n 
A 1 200 SER 200 200 200 SER SER A . n 
A 1 201 PHE 201 201 201 PHE PHE A . n 
A 1 202 ARG 202 202 202 ARG ARG A . n 
A 1 203 GLU 203 203 203 GLU GLU A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 GLU 205 205 205 GLU GLU A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 LYS 207 207 207 LYS LYS A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 ILE 209 209 209 ILE ILE A . n 
A 1 210 ASP 210 210 210 ASP ASP A . n 
A 1 211 LEU 211 211 211 LEU LEU A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 SER 213 213 213 SER SER A . n 
A 1 214 THR 214 214 214 THR THR A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 LYS 218 218 218 LYS LYS A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 PRO 222 222 222 PRO PRO A . n 
A 1 223 VAL 223 223 223 VAL VAL A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 PRO 225 225 225 PRO PRO A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 VAL 227 227 227 VAL VAL A . n 
A 1 228 GLN 228 228 ?   ?   ?   A . n 
A 1 229 ASP 229 229 ?   ?   ?   A . n 
A 1 230 PRO 230 230 ?   ?   ?   A . n 
A 1 231 MET 231 231 ?   ?   ?   A . n 
A 1 232 GLY 232 232 ?   ?   ?   A . n 
A 1 233 HIS 233 233 ?   ?   ?   A . n 
A 1 234 ASN 234 234 ?   ?   ?   A . n 
A 1 235 GLU 235 235 ?   ?   ?   A . n 
A 1 236 ASP 236 236 236 ASP ASP A . n 
A 1 237 PRO 237 237 237 PRO PRO A . n 
A 1 238 LYS 238 238 238 LYS LYS A . n 
A 1 239 THR 239 239 239 THR THR A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 GLN 241 241 241 GLN GLN A . n 
A 1 242 ILE 242 242 242 ILE ILE A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 ASN 244 244 244 ASN ASN A . n 
A 1 245 TRP 245 245 245 TRP TRP A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 ASP 247 247 247 ASP ASP A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 GLU 251 251 251 GLU GLU A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 THR 253 253 253 THR THR A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 VAL 255 255 255 VAL VAL A . n 
A 1 256 PHE 256 256 256 PHE PHE A . n 
A 1 257 VAL 257 257 257 VAL VAL A . n 
A 1 258 CYS 258 258 258 CYS CYS A . n 
A 1 259 PHE 259 259 259 PHE PHE A . n 
A 1 260 GLY 260 260 260 GLY GLY A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 GLU 262 262 262 GLU GLU A . n 
A 1 263 TYR 263 263 263 TYR TYR A . n 
A 1 264 PHE 264 264 264 PHE PHE A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 SER 266 266 266 SER SER A . n 
A 1 267 ASN 267 267 267 ASN ASN A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 GLU 269 269 269 GLU GLU A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 GLU 271 271 271 GLU GLU A . n 
A 1 272 GLU 272 272 272 GLU GLU A . n 
A 1 273 VAL 273 273 273 VAL VAL A . n 
A 1 274 ALA 274 274 274 ALA ALA A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 GLY 276 276 276 GLY GLY A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 GLU 278 278 278 GLU GLU A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 SER 280 280 280 SER SER A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 VAL 282 282 282 VAL VAL A . n 
A 1 283 ASN 283 283 283 ASN ASN A . n 
A 1 284 PHE 284 284 284 PHE PHE A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 TRP 286 286 286 TRP TRP A . n 
A 1 287 ALA 287 287 287 ALA ALA A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 ARG 289 289 ?   ?   ?   A . n 
A 1 290 LEU 290 290 ?   ?   ?   A . n 
A 1 291 ILE 291 291 ?   ?   ?   A . n 
A 1 292 GLU 292 292 ?   ?   ?   A . n 
A 1 293 GLY 293 293 ?   ?   ?   A . n 
A 1 294 GLU 294 294 ?   ?   ?   A . n 
A 1 295 LYS 295 295 ?   ?   ?   A . n 
A 1 296 LYS 296 296 ?   ?   ?   A . n 
A 1 297 GLY 297 297 ?   ?   ?   A . n 
A 1 298 ILE 298 298 ?   ?   ?   A . n 
A 1 299 LEU 299 299 ?   ?   ?   A . n 
A 1 300 PRO 300 300 ?   ?   ?   A . n 
A 1 301 GLU 301 301 ?   ?   ?   A . n 
A 1 302 GLY 302 302 ?   ?   ?   A . n 
A 1 303 PHE 303 303 303 PHE PHE A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 GLN 305 305 305 GLN GLN A . n 
A 1 306 ARG 306 306 306 ARG ARG A . n 
A 1 307 VAL 307 307 307 VAL VAL A . n 
A 1 308 GLY 308 308 308 GLY GLY A . n 
A 1 309 ASP 309 309 309 ASP ASP A . n 
A 1 310 ARG 310 310 310 ARG ARG A . n 
A 1 311 GLY 311 311 311 GLY GLY A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 VAL 314 314 314 VAL VAL A . n 
A 1 315 GLU 315 315 315 GLU GLU A . n 
A 1 316 GLY 316 316 316 GLY GLY A . n 
A 1 317 TRP 317 317 317 TRP TRP A . n 
A 1 318 ALA 318 318 318 ALA ALA A . n 
A 1 319 PRO 319 319 319 PRO PRO A . n 
A 1 320 GLN 320 320 320 GLN GLN A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 ARG 322 322 322 ARG ARG A . n 
A 1 323 ILE 323 323 323 ILE ILE A . n 
A 1 324 LEU 324 324 324 LEU LEU A . n 
A 1 325 GLY 325 325 325 GLY GLY A . n 
A 1 326 HIS 326 326 326 HIS HIS A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 SER 328 328 328 SER SER A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 GLY 330 330 330 GLY GLY A . n 
A 1 331 GLY 331 331 331 GLY GLY A . n 
A 1 332 PHE 332 332 332 PHE PHE A . n 
A 1 333 VAL 333 333 333 VAL VAL A . n 
A 1 334 SER 334 334 334 SER SER A . n 
A 1 335 HIS 335 335 335 HIS HIS A . n 
A 1 336 CYS 336 336 336 CYS CYS A . n 
A 1 337 GLY 337 337 337 GLY GLY A . n 
A 1 338 TRP 338 338 338 TRP TRP A . n 
A 1 339 SER 339 339 339 SER SER A . n 
A 1 340 SER 340 340 340 SER SER A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 ALA 342 342 342 ALA ALA A . n 
A 1 343 GLU 343 343 343 GLU GLU A . n 
A 1 344 SER 344 344 344 SER SER A . n 
A 1 345 MET 345 345 345 MET MET A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 GLY 348 348 348 GLY GLY A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 PRO 350 350 350 PRO PRO A . n 
A 1 351 VAL 351 351 351 VAL VAL A . n 
A 1 352 ILE 352 352 352 ILE ILE A . n 
A 1 353 ALA 353 353 353 ALA ALA A . n 
A 1 354 MET 354 354 354 MET MET A . n 
A 1 355 ALA 355 355 355 ALA ALA A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 HIS 357 357 357 HIS HIS A . n 
A 1 358 LEU 358 358 358 LEU LEU A . n 
A 1 359 ASP 359 359 359 ASP ASP A . n 
A 1 360 GLN 360 360 360 GLN GLN A . n 
A 1 361 PRO 361 361 361 PRO PRO A . n 
A 1 362 LEU 362 362 362 LEU LEU A . n 
A 1 363 ASN 363 363 363 ASN ASN A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 LYS 365 365 365 LYS LYS A . n 
A 1 366 LEU 366 366 366 LEU LEU A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 GLU 369 369 369 GLU GLU A . n 
A 1 370 VAL 370 370 370 VAL VAL A . n 
A 1 371 GLY 371 371 371 GLY GLY A . n 
A 1 372 VAL 372 372 372 VAL VAL A . n 
A 1 373 GLY 373 373 373 GLY GLY A . n 
A 1 374 MET 374 374 374 MET MET A . n 
A 1 375 GLU 375 375 375 GLU GLU A . n 
A 1 376 VAL 376 376 376 VAL VAL A . n 
A 1 377 VAL 377 377 377 VAL VAL A . n 
A 1 378 ARG 378 378 378 ARG ARG A . n 
A 1 379 ASP 379 379 379 ASP ASP A . n 
A 1 380 GLU 380 380 380 GLU GLU A . n 
A 1 381 ASN 381 381 381 ASN ASN A . n 
A 1 382 GLY 382 382 382 GLY GLY A . n 
A 1 383 LYS 383 383 383 LYS LYS A . n 
A 1 384 TYR 384 384 384 TYR TYR A . n 
A 1 385 LYS 385 385 385 LYS LYS A . n 
A 1 386 ARG 386 386 386 ARG ARG A . n 
A 1 387 GLU 387 387 387 GLU GLU A . n 
A 1 388 GLY 388 388 388 GLY GLY A . n 
A 1 389 ILE 389 389 389 ILE ILE A . n 
A 1 390 ALA 390 390 390 ALA ALA A . n 
A 1 391 GLU 391 391 391 GLU GLU A . n 
A 1 392 VAL 392 392 392 VAL VAL A . n 
A 1 393 ILE 393 393 393 ILE ILE A . n 
A 1 394 ARG 394 394 394 ARG ARG A . n 
A 1 395 LYS 395 395 395 LYS LYS A . n 
A 1 396 VAL 396 396 396 VAL VAL A . n 
A 1 397 VAL 397 397 397 VAL VAL A . n 
A 1 398 VAL 398 398 398 VAL VAL A . n 
A 1 399 GLU 399 399 399 GLU GLU A . n 
A 1 400 LYS 400 400 400 LYS LYS A . n 
A 1 401 SER 401 401 401 SER SER A . n 
A 1 402 GLY 402 402 402 GLY GLY A . n 
A 1 403 GLU 403 403 403 GLU GLU A . n 
A 1 404 VAL 404 404 404 VAL VAL A . n 
A 1 405 ILE 405 405 405 ILE ILE A . n 
A 1 406 ARG 406 406 406 ARG ARG A . n 
A 1 407 ARG 407 407 407 ARG ARG A . n 
A 1 408 LYS 408 408 408 LYS LYS A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 ARG 410 410 410 ARG ARG A . n 
A 1 411 GLU 411 411 411 GLU GLU A . n 
A 1 412 LEU 412 412 412 LEU LEU A . n 
A 1 413 SER 413 413 413 SER SER A . n 
A 1 414 GLU 414 414 414 GLU GLU A . n 
A 1 415 LYS 415 415 415 LYS LYS A . n 
A 1 416 MET 416 416 416 MET MET A . n 
A 1 417 LYS 417 417 417 LYS LYS A . n 
A 1 418 GLU 418 418 418 GLU GLU A . n 
A 1 419 LYS 419 419 419 LYS LYS A . n 
A 1 420 GLY 420 420 420 GLY GLY A . n 
A 1 421 GLU 421 421 421 GLU GLU A . n 
A 1 422 GLN 422 422 422 GLN GLN A . n 
A 1 423 GLU 423 423 423 GLU GLU A . n 
A 1 424 ILE 424 424 424 ILE ILE A . n 
A 1 425 ASP 425 425 425 ASP ASP A . n 
A 1 426 ARG 426 426 426 ARG ARG A . n 
A 1 427 ALA 427 427 427 ALA ALA A . n 
A 1 428 VAL 428 428 428 VAL VAL A . n 
A 1 429 GLU 429 429 429 GLU GLU A . n 
A 1 430 GLU 430 430 430 GLU GLU A . n 
A 1 431 LEU 431 431 431 LEU LEU A . n 
A 1 432 VAL 432 432 432 VAL VAL A . n 
A 1 433 GLN 433 433 433 GLN GLN A . n 
A 1 434 ILE 434 434 434 ILE ILE A . n 
A 1 435 CYS 435 435 435 CYS CYS A . n 
A 1 436 LYS 436 436 436 LYS LYS A . n 
A 1 437 LYS 437 437 437 LYS LYS A . n 
A 1 438 LYS 438 438 438 LYS LYS A . n 
A 1 439 LYS 439 439 439 LYS LYS A . n 
A 1 440 ASP 440 440 440 ASP ASP A . n 
A 1 441 GLU 441 441 441 GLU GLU A . n 
A 1 442 GLN 442 442 442 GLN GLN A . n 
A 1 443 GLU 443 443 ?   ?   ?   A . n 
A 1 444 ASN 444 444 ?   ?   ?   A . n 
A 1 445 LEU 445 445 ?   ?   ?   A . n 
A 1 446 TYR 446 446 ?   ?   ?   A . n 
A 1 447 PHE 447 447 ?   ?   ?   A . n 
A 1 448 GLN 448 448 ?   ?   ?   A . n 
A 1 449 GLY 449 449 ?   ?   ?   A . n 
A 1 450 HIS 450 450 ?   ?   ?   A . n 
A 1 451 HIS 451 451 ?   ?   ?   A . n 
A 1 452 HIS 452 452 ?   ?   ?   A . n 
A 1 453 HIS 453 453 ?   ?   ?   A . n 
A 1 454 HIS 454 454 ?   ?   ?   A . n 
A 1 455 HIS 455 455 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ASP 2   2   ?   ?   ?   B . n 
B 1 3   ASN 3   3   ?   ?   ?   B . n 
B 1 4   GLN 4   4   ?   ?   ?   B . n 
B 1 5   LYS 5   5   ?   ?   ?   B . n 
B 1 6   GLY 6   6   ?   ?   ?   B . n 
B 1 7   ARG 7   7   ?   ?   ?   B . n 
B 1 8   ILE 8   8   8   ILE ILE B . n 
B 1 9   SER 9   9   9   SER SER B . n 
B 1 10  ILE 10  10  10  ILE ILE B . n 
B 1 11  ALA 11  11  11  ALA ALA B . n 
B 1 12  LEU 12  12  12  LEU LEU B . n 
B 1 13  LEU 13  13  13  LEU LEU B . n 
B 1 14  PRO 14  14  14  PRO PRO B . n 
B 1 15  PHE 15  15  15  PHE PHE B . n 
B 1 16  LEU 16  16  16  LEU LEU B . n 
B 1 17  ALA 17  17  17  ALA ALA B . n 
B 1 18  HIS 18  18  18  HIS HIS B . n 
B 1 19  GLY 19  19  19  GLY GLY B . n 
B 1 20  HIS 20  20  20  HIS HIS B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  SER 22  22  22  SER SER B . n 
B 1 23  PRO 23  23  23  PRO PRO B . n 
B 1 24  PHE 24  24  24  PHE PHE B . n 
B 1 25  PHE 25  25  25  PHE PHE B . n 
B 1 26  GLU 26  26  26  GLU GLU B . n 
B 1 27  LEU 27  27  27  LEU LEU B . n 
B 1 28  ALA 28  28  28  ALA ALA B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  GLN 30  30  30  GLN GLN B . n 
B 1 31  LEU 31  31  31  LEU LEU B . n 
B 1 32  ALA 32  32  32  ALA ALA B . n 
B 1 33  LYS 33  33  33  LYS LYS B . n 
B 1 34  ARG 34  34  34  ARG ARG B . n 
B 1 35  ASN 35  35  35  ASN ASN B . n 
B 1 36  CYS 36  36  36  CYS CYS B . n 
B 1 37  ASN 37  37  37  ASN ASN B . n 
B 1 38  VAL 38  38  38  VAL VAL B . n 
B 1 39  PHE 39  39  39  PHE PHE B . n 
B 1 40  LEU 40  40  40  LEU LEU B . n 
B 1 41  CYS 41  41  41  CYS CYS B . n 
B 1 42  SER 42  42  42  SER SER B . n 
B 1 43  THR 43  43  43  THR THR B . n 
B 1 44  PRO 44  44  44  PRO PRO B . n 
B 1 45  ILE 45  45  45  ILE ILE B . n 
B 1 46  ASN 46  46  46  ASN ASN B . n 
B 1 47  LEU 47  47  47  LEU LEU B . n 
B 1 48  SER 48  48  48  SER SER B . n 
B 1 49  SER 49  49  49  SER SER B . n 
B 1 50  ILE 50  50  50  ILE ILE B . n 
B 1 51  LYS 51  51  51  LYS LYS B . n 
B 1 52  ASP 52  52  52  ASP ASP B . n 
B 1 53  LYS 53  53  53  LYS LYS B . n 
B 1 54  ASP 54  54  54  ASP ASP B . n 
B 1 55  SER 55  55  55  SER SER B . n 
B 1 56  SER 56  56  56  SER SER B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  SER 58  58  58  SER SER B . n 
B 1 59  ILE 59  59  59  ILE ILE B . n 
B 1 60  LYS 60  60  60  LYS LYS B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  VAL 62  62  62  VAL VAL B . n 
B 1 63  GLU 63  63  63  GLU GLU B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  HIS 65  65  65  HIS HIS B . n 
B 1 66  LEU 66  66  ?   ?   ?   B . n 
B 1 67  PRO 67  67  ?   ?   ?   B . n 
B 1 68  SER 68  68  ?   ?   ?   B . n 
B 1 69  SER 69  69  ?   ?   ?   B . n 
B 1 70  PRO 70  70  ?   ?   ?   B . n 
B 1 71  ASP 71  71  ?   ?   ?   B . n 
B 1 72  LEU 72  72  ?   ?   ?   B . n 
B 1 73  PRO 73  73  ?   ?   ?   B . n 
B 1 74  PRO 74  74  ?   ?   ?   B . n 
B 1 75  HIS 75  75  ?   ?   ?   B . n 
B 1 76  TYR 76  76  ?   ?   ?   B . n 
B 1 77  HIS 77  77  ?   ?   ?   B . n 
B 1 78  THR 78  78  ?   ?   ?   B . n 
B 1 79  THR 79  79  ?   ?   ?   B . n 
B 1 80  ASN 80  80  ?   ?   ?   B . n 
B 1 81  GLY 81  81  ?   ?   ?   B . n 
B 1 82  LEU 82  82  ?   ?   ?   B . n 
B 1 83  PRO 83  83  ?   ?   ?   B . n 
B 1 84  SER 84  84  ?   ?   ?   B . n 
B 1 85  HIS 85  85  ?   ?   ?   B . n 
B 1 86  LEU 86  86  ?   ?   ?   B . n 
B 1 87  MET 87  87  ?   ?   ?   B . n 
B 1 88  LEU 88  88  ?   ?   ?   B . n 
B 1 89  PRO 89  89  ?   ?   ?   B . n 
B 1 90  LEU 90  90  ?   ?   ?   B . n 
B 1 91  ARG 91  91  91  ARG ARG B . n 
B 1 92  ASN 92  92  92  ASN ASN B . n 
B 1 93  ALA 93  93  93  ALA ALA B . n 
B 1 94  PHE 94  94  94  PHE PHE B . n 
B 1 95  GLU 95  95  95  GLU GLU B . n 
B 1 96  THR 96  96  96  THR THR B . n 
B 1 97  ALA 97  97  97  ALA ALA B . n 
B 1 98  GLY 98  98  98  GLY GLY B . n 
B 1 99  PRO 99  99  99  PRO PRO B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 PHE 101 101 101 PHE PHE B . n 
B 1 102 SER 102 102 102 SER SER B . n 
B 1 103 GLU 103 103 103 GLU GLU B . n 
B 1 104 ILE 104 104 104 ILE ILE B . n 
B 1 105 LEU 105 105 105 LEU LEU B . n 
B 1 106 LYS 106 106 106 LYS LYS B . n 
B 1 107 THR 107 107 107 THR THR B . n 
B 1 108 LEU 108 108 108 LEU LEU B . n 
B 1 109 ASN 109 109 109 ASN ASN B . n 
B 1 110 PRO 110 110 110 PRO PRO B . n 
B 1 111 ASP 111 111 111 ASP ASP B . n 
B 1 112 LEU 112 112 112 LEU LEU B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 ILE 114 114 114 ILE ILE B . n 
B 1 115 TYR 115 115 115 TYR TYR B . n 
B 1 116 ASP 116 116 116 ASP ASP B . n 
B 1 117 PHE 117 117 117 PHE PHE B . n 
B 1 118 ASN 118 118 118 ASN ASN B . n 
B 1 119 PRO 119 119 119 PRO PRO B . n 
B 1 120 SER 120 120 120 SER SER B . n 
B 1 121 TRP 121 121 121 TRP TRP B . n 
B 1 122 ALA 122 122 122 ALA ALA B . n 
B 1 123 PRO 123 123 123 PRO PRO B . n 
B 1 124 GLU 124 124 124 GLU GLU B . n 
B 1 125 ILE 125 125 125 ILE ILE B . n 
B 1 126 ALA 126 126 126 ALA ALA B . n 
B 1 127 SER 127 127 127 SER SER B . n 
B 1 128 SER 128 128 128 SER SER B . n 
B 1 129 HIS 129 129 129 HIS HIS B . n 
B 1 130 ASN 130 130 130 ASN ASN B . n 
B 1 131 ILE 131 131 131 ILE ILE B . n 
B 1 132 PRO 132 132 132 PRO PRO B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 VAL 134 134 134 VAL VAL B . n 
B 1 135 TYR 135 135 135 TYR TYR B . n 
B 1 136 PHE 136 136 136 PHE PHE B . n 
B 1 137 LEU 137 137 137 LEU LEU B . n 
B 1 138 THR 138 138 138 THR THR B . n 
B 1 139 THR 139 139 139 THR THR B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 ALA 141 141 141 ALA ALA B . n 
B 1 142 ALA 142 142 142 ALA ALA B . n 
B 1 143 SER 143 143 143 SER SER B . n 
B 1 144 SER 144 144 144 SER SER B . n 
B 1 145 SER 145 145 145 SER SER B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 GLY 147 147 147 GLY GLY B . n 
B 1 148 LEU 148 148 148 LEU LEU B . n 
B 1 149 HIS 149 149 149 HIS HIS B . n 
B 1 150 ALA 150 150 150 ALA ALA B . n 
B 1 151 PHE 151 151 151 PHE PHE B . n 
B 1 152 LYS 152 152 152 LYS LYS B . n 
B 1 153 ASN 153 153 153 ASN ASN B . n 
B 1 154 PRO 154 154 154 PRO PRO B . n 
B 1 155 GLY 155 155 155 GLY GLY B . n 
B 1 156 GLU 156 156 156 GLU GLU B . n 
B 1 157 LYS 157 157 157 LYS LYS B . n 
B 1 158 TYR 158 158 158 TYR TYR B . n 
B 1 159 PRO 159 159 159 PRO PRO B . n 
B 1 160 PHE 160 160 160 PHE PHE B . n 
B 1 161 PRO 161 161 161 PRO PRO B . n 
B 1 162 ASP 162 162 162 ASP ASP B . n 
B 1 163 PHE 163 163 163 PHE PHE B . n 
B 1 164 TYR 164 164 164 TYR TYR B . n 
B 1 165 ASP 165 165 165 ASP ASP B . n 
B 1 166 ASN 166 166 166 ASN ASN B . n 
B 1 167 SER 167 167 167 SER SER B . n 
B 1 168 ASN 168 168 ?   ?   ?   B . n 
B 1 169 ILE 169 169 ?   ?   ?   B . n 
B 1 170 ILE 170 170 ?   ?   ?   B . n 
B 1 171 PRO 171 171 ?   ?   ?   B . n 
B 1 172 GLU 172 172 ?   ?   ?   B . n 
B 1 173 PRO 173 173 ?   ?   ?   B . n 
B 1 174 PRO 174 174 ?   ?   ?   B . n 
B 1 175 SER 175 175 ?   ?   ?   B . n 
B 1 176 ALA 176 176 ?   ?   ?   B . n 
B 1 177 ASP 177 177 ?   ?   ?   B . n 
B 1 178 ASN 178 178 178 ASN ASN B . n 
B 1 179 MET 179 179 179 MET MET B . n 
B 1 180 LYS 180 180 180 LYS LYS B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 HIS 183 183 183 HIS HIS B . n 
B 1 184 ASP 184 184 184 ASP ASP B . n 
B 1 185 PHE 185 185 185 PHE PHE B . n 
B 1 186 ILE 186 186 186 ILE ILE B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 CYS 188 188 188 CYS CYS B . n 
B 1 189 PHE 189 189 189 PHE PHE B . n 
B 1 190 GLU 190 190 190 GLU GLU B . n 
B 1 191 ARG 191 191 191 ARG ARG B . n 
B 1 192 SER 192 192 192 SER SER B . n 
B 1 193 CYS 193 193 193 CYS CYS B . n 
B 1 194 ASP 194 194 194 ASP ASP B . n 
B 1 195 ILE 195 195 195 ILE ILE B . n 
B 1 196 ILE 196 196 196 ILE ILE B . n 
B 1 197 LEU 197 197 197 LEU LEU B . n 
B 1 198 ILE 198 198 198 ILE ILE B . n 
B 1 199 LYS 199 199 199 LYS LYS B . n 
B 1 200 SER 200 200 200 SER SER B . n 
B 1 201 PHE 201 201 201 PHE PHE B . n 
B 1 202 ARG 202 202 202 ARG ARG B . n 
B 1 203 GLU 203 203 203 GLU GLU B . n 
B 1 204 LEU 204 204 204 LEU LEU B . n 
B 1 205 GLU 205 205 205 GLU GLU B . n 
B 1 206 GLY 206 206 206 GLY GLY B . n 
B 1 207 LYS 207 207 207 LYS LYS B . n 
B 1 208 TYR 208 208 208 TYR TYR B . n 
B 1 209 ILE 209 209 209 ILE ILE B . n 
B 1 210 ASP 210 210 210 ASP ASP B . n 
B 1 211 LEU 211 211 211 LEU LEU B . n 
B 1 212 LEU 212 212 212 LEU LEU B . n 
B 1 213 SER 213 213 213 SER SER B . n 
B 1 214 THR 214 214 214 THR THR B . n 
B 1 215 LEU 215 215 215 LEU LEU B . n 
B 1 216 SER 216 216 216 SER SER B . n 
B 1 217 ASP 217 217 217 ASP ASP B . n 
B 1 218 LYS 218 218 218 LYS LYS B . n 
B 1 219 THR 219 219 219 THR THR B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 VAL 221 221 221 VAL VAL B . n 
B 1 222 PRO 222 222 222 PRO PRO B . n 
B 1 223 VAL 223 223 223 VAL VAL B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 PRO 225 225 225 PRO PRO B . n 
B 1 226 LEU 226 226 226 LEU LEU B . n 
B 1 227 VAL 227 227 227 VAL VAL B . n 
B 1 228 GLN 228 228 ?   ?   ?   B . n 
B 1 229 ASP 229 229 ?   ?   ?   B . n 
B 1 230 PRO 230 230 ?   ?   ?   B . n 
B 1 231 MET 231 231 ?   ?   ?   B . n 
B 1 232 GLY 232 232 ?   ?   ?   B . n 
B 1 233 HIS 233 233 ?   ?   ?   B . n 
B 1 234 ASN 234 234 ?   ?   ?   B . n 
B 1 235 GLU 235 235 ?   ?   ?   B . n 
B 1 236 ASP 236 236 236 ASP ASP B . n 
B 1 237 PRO 237 237 237 PRO PRO B . n 
B 1 238 LYS 238 238 238 LYS LYS B . n 
B 1 239 THR 239 239 239 THR THR B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 GLN 241 241 241 GLN GLN B . n 
B 1 242 ILE 242 242 242 ILE ILE B . n 
B 1 243 ILE 243 243 243 ILE ILE B . n 
B 1 244 ASN 244 244 244 ASN ASN B . n 
B 1 245 TRP 245 245 245 TRP TRP B . n 
B 1 246 LEU 246 246 246 LEU LEU B . n 
B 1 247 ASP 247 247 247 ASP ASP B . n 
B 1 248 LYS 248 248 248 LYS LYS B . n 
B 1 249 ARG 249 249 249 ARG ARG B . n 
B 1 250 ALA 250 250 250 ALA ALA B . n 
B 1 251 GLU 251 251 251 GLU GLU B . n 
B 1 252 SER 252 252 252 SER SER B . n 
B 1 253 THR 253 253 253 THR THR B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 VAL 255 255 255 VAL VAL B . n 
B 1 256 PHE 256 256 256 PHE PHE B . n 
B 1 257 VAL 257 257 257 VAL VAL B . n 
B 1 258 CYS 258 258 258 CYS CYS B . n 
B 1 259 PHE 259 259 259 PHE PHE B . n 
B 1 260 GLY 260 260 260 GLY GLY B . n 
B 1 261 SER 261 261 261 SER SER B . n 
B 1 262 GLU 262 262 262 GLU GLU B . n 
B 1 263 TYR 263 263 263 TYR TYR B . n 
B 1 264 PHE 264 264 264 PHE PHE B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 SER 266 266 266 SER SER B . n 
B 1 267 ASN 267 267 267 ASN ASN B . n 
B 1 268 GLU 268 268 268 GLU GLU B . n 
B 1 269 GLU 269 269 269 GLU GLU B . n 
B 1 270 LEU 270 270 270 LEU LEU B . n 
B 1 271 GLU 271 271 271 GLU GLU B . n 
B 1 272 GLU 272 272 272 GLU GLU B . n 
B 1 273 VAL 273 273 273 VAL VAL B . n 
B 1 274 ALA 274 274 274 ALA ALA B . n 
B 1 275 ILE 275 275 275 ILE ILE B . n 
B 1 276 GLY 276 276 276 GLY GLY B . n 
B 1 277 LEU 277 277 277 LEU LEU B . n 
B 1 278 GLU 278 278 278 GLU GLU B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 SER 280 280 280 SER SER B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 VAL 282 282 282 VAL VAL B . n 
B 1 283 ASN 283 283 283 ASN ASN B . n 
B 1 284 PHE 284 284 284 PHE PHE B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 TRP 286 286 286 TRP TRP B . n 
B 1 287 ALA 287 287 287 ALA ALA B . n 
B 1 288 VAL 288 288 288 VAL VAL B . n 
B 1 289 ARG 289 289 ?   ?   ?   B . n 
B 1 290 LEU 290 290 ?   ?   ?   B . n 
B 1 291 ILE 291 291 ?   ?   ?   B . n 
B 1 292 GLU 292 292 ?   ?   ?   B . n 
B 1 293 GLY 293 293 ?   ?   ?   B . n 
B 1 294 GLU 294 294 ?   ?   ?   B . n 
B 1 295 LYS 295 295 ?   ?   ?   B . n 
B 1 296 LYS 296 296 ?   ?   ?   B . n 
B 1 297 GLY 297 297 ?   ?   ?   B . n 
B 1 298 ILE 298 298 ?   ?   ?   B . n 
B 1 299 LEU 299 299 ?   ?   ?   B . n 
B 1 300 PRO 300 300 ?   ?   ?   B . n 
B 1 301 GLU 301 301 ?   ?   ?   B . n 
B 1 302 GLY 302 302 ?   ?   ?   B . n 
B 1 303 PHE 303 303 303 PHE PHE B . n 
B 1 304 VAL 304 304 304 VAL VAL B . n 
B 1 305 GLN 305 305 305 GLN GLN B . n 
B 1 306 ARG 306 306 306 ARG ARG B . n 
B 1 307 VAL 307 307 307 VAL VAL B . n 
B 1 308 GLY 308 308 308 GLY GLY B . n 
B 1 309 ASP 309 309 309 ASP ASP B . n 
B 1 310 ARG 310 310 310 ARG ARG B . n 
B 1 311 GLY 311 311 311 GLY GLY B . n 
B 1 312 LEU 312 312 312 LEU LEU B . n 
B 1 313 VAL 313 313 313 VAL VAL B . n 
B 1 314 VAL 314 314 314 VAL VAL B . n 
B 1 315 GLU 315 315 315 GLU GLU B . n 
B 1 316 GLY 316 316 316 GLY GLY B . n 
B 1 317 TRP 317 317 317 TRP TRP B . n 
B 1 318 ALA 318 318 318 ALA ALA B . n 
B 1 319 PRO 319 319 319 PRO PRO B . n 
B 1 320 GLN 320 320 320 GLN GLN B . n 
B 1 321 ALA 321 321 321 ALA ALA B . n 
B 1 322 ARG 322 322 322 ARG ARG B . n 
B 1 323 ILE 323 323 323 ILE ILE B . n 
B 1 324 LEU 324 324 324 LEU LEU B . n 
B 1 325 GLY 325 325 325 GLY GLY B . n 
B 1 326 HIS 326 326 326 HIS HIS B . n 
B 1 327 SER 327 327 327 SER SER B . n 
B 1 328 SER 328 328 328 SER SER B . n 
B 1 329 THR 329 329 329 THR THR B . n 
B 1 330 GLY 330 330 330 GLY GLY B . n 
B 1 331 GLY 331 331 331 GLY GLY B . n 
B 1 332 PHE 332 332 332 PHE PHE B . n 
B 1 333 VAL 333 333 333 VAL VAL B . n 
B 1 334 SER 334 334 334 SER SER B . n 
B 1 335 HIS 335 335 335 HIS HIS B . n 
B 1 336 CYS 336 336 336 CYS CYS B . n 
B 1 337 GLY 337 337 337 GLY GLY B . n 
B 1 338 TRP 338 338 338 TRP TRP B . n 
B 1 339 SER 339 339 339 SER SER B . n 
B 1 340 SER 340 340 340 SER SER B . n 
B 1 341 ILE 341 341 341 ILE ILE B . n 
B 1 342 ALA 342 342 342 ALA ALA B . n 
B 1 343 GLU 343 343 343 GLU GLU B . n 
B 1 344 SER 344 344 344 SER SER B . n 
B 1 345 MET 345 345 345 MET MET B . n 
B 1 346 LYS 346 346 346 LYS LYS B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 GLY 348 348 348 GLY GLY B . n 
B 1 349 VAL 349 349 349 VAL VAL B . n 
B 1 350 PRO 350 350 350 PRO PRO B . n 
B 1 351 VAL 351 351 351 VAL VAL B . n 
B 1 352 ILE 352 352 352 ILE ILE B . n 
B 1 353 ALA 353 353 353 ALA ALA B . n 
B 1 354 MET 354 354 354 MET MET B . n 
B 1 355 ALA 355 355 355 ALA ALA B . n 
B 1 356 ARG 356 356 356 ARG ARG B . n 
B 1 357 HIS 357 357 357 HIS HIS B . n 
B 1 358 LEU 358 358 358 LEU LEU B . n 
B 1 359 ASP 359 359 359 ASP ASP B . n 
B 1 360 GLN 360 360 360 GLN GLN B . n 
B 1 361 PRO 361 361 361 PRO PRO B . n 
B 1 362 LEU 362 362 362 LEU LEU B . n 
B 1 363 ASN 363 363 363 ASN ASN B . n 
B 1 364 GLY 364 364 364 GLY GLY B . n 
B 1 365 LYS 365 365 365 LYS LYS B . n 
B 1 366 LEU 366 366 366 LEU LEU B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 ALA 368 368 368 ALA ALA B . n 
B 1 369 GLU 369 369 369 GLU GLU B . n 
B 1 370 VAL 370 370 370 VAL VAL B . n 
B 1 371 GLY 371 371 371 GLY GLY B . n 
B 1 372 VAL 372 372 372 VAL VAL B . n 
B 1 373 GLY 373 373 373 GLY GLY B . n 
B 1 374 MET 374 374 374 MET MET B . n 
B 1 375 GLU 375 375 375 GLU GLU B . n 
B 1 376 VAL 376 376 376 VAL VAL B . n 
B 1 377 VAL 377 377 377 VAL VAL B . n 
B 1 378 ARG 378 378 378 ARG ARG B . n 
B 1 379 ASP 379 379 379 ASP ASP B . n 
B 1 380 GLU 380 380 380 GLU GLU B . n 
B 1 381 ASN 381 381 381 ASN ASN B . n 
B 1 382 GLY 382 382 382 GLY GLY B . n 
B 1 383 LYS 383 383 383 LYS LYS B . n 
B 1 384 TYR 384 384 384 TYR TYR B . n 
B 1 385 LYS 385 385 385 LYS LYS B . n 
B 1 386 ARG 386 386 386 ARG ARG B . n 
B 1 387 GLU 387 387 387 GLU GLU B . n 
B 1 388 GLY 388 388 388 GLY GLY B . n 
B 1 389 ILE 389 389 389 ILE ILE B . n 
B 1 390 ALA 390 390 390 ALA ALA B . n 
B 1 391 GLU 391 391 391 GLU GLU B . n 
B 1 392 VAL 392 392 392 VAL VAL B . n 
B 1 393 ILE 393 393 393 ILE ILE B . n 
B 1 394 ARG 394 394 394 ARG ARG B . n 
B 1 395 LYS 395 395 395 LYS LYS B . n 
B 1 396 VAL 396 396 396 VAL VAL B . n 
B 1 397 VAL 397 397 397 VAL VAL B . n 
B 1 398 VAL 398 398 398 VAL VAL B . n 
B 1 399 GLU 399 399 399 GLU GLU B . n 
B 1 400 LYS 400 400 400 LYS LYS B . n 
B 1 401 SER 401 401 401 SER SER B . n 
B 1 402 GLY 402 402 402 GLY GLY B . n 
B 1 403 GLU 403 403 403 GLU GLU B . n 
B 1 404 VAL 404 404 404 VAL VAL B . n 
B 1 405 ILE 405 405 405 ILE ILE B . n 
B 1 406 ARG 406 406 406 ARG ARG B . n 
B 1 407 ARG 407 407 407 ARG ARG B . n 
B 1 408 LYS 408 408 408 LYS LYS B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 ARG 410 410 410 ARG ARG B . n 
B 1 411 GLU 411 411 411 GLU GLU B . n 
B 1 412 LEU 412 412 412 LEU LEU B . n 
B 1 413 SER 413 413 413 SER SER B . n 
B 1 414 GLU 414 414 414 GLU GLU B . n 
B 1 415 LYS 415 415 415 LYS LYS B . n 
B 1 416 MET 416 416 416 MET MET B . n 
B 1 417 LYS 417 417 417 LYS LYS B . n 
B 1 418 GLU 418 418 418 GLU GLU B . n 
B 1 419 LYS 419 419 419 LYS LYS B . n 
B 1 420 GLY 420 420 420 GLY GLY B . n 
B 1 421 GLU 421 421 421 GLU GLU B . n 
B 1 422 GLN 422 422 422 GLN GLN B . n 
B 1 423 GLU 423 423 423 GLU GLU B . n 
B 1 424 ILE 424 424 424 ILE ILE B . n 
B 1 425 ASP 425 425 425 ASP ASP B . n 
B 1 426 ARG 426 426 426 ARG ARG B . n 
B 1 427 ALA 427 427 427 ALA ALA B . n 
B 1 428 VAL 428 428 428 VAL VAL B . n 
B 1 429 GLU 429 429 429 GLU GLU B . n 
B 1 430 GLU 430 430 430 GLU GLU B . n 
B 1 431 LEU 431 431 431 LEU LEU B . n 
B 1 432 VAL 432 432 432 VAL VAL B . n 
B 1 433 GLN 433 433 433 GLN GLN B . n 
B 1 434 ILE 434 434 434 ILE ILE B . n 
B 1 435 CYS 435 435 435 CYS CYS B . n 
B 1 436 LYS 436 436 436 LYS LYS B . n 
B 1 437 LYS 437 437 437 LYS LYS B . n 
B 1 438 LYS 438 438 438 LYS LYS B . n 
B 1 439 LYS 439 439 439 LYS LYS B . n 
B 1 440 ASP 440 440 440 ASP ASP B . n 
B 1 441 GLU 441 441 441 GLU GLU B . n 
B 1 442 GLN 442 442 442 GLN GLN B . n 
B 1 443 GLU 443 443 ?   ?   ?   B . n 
B 1 444 ASN 444 444 ?   ?   ?   B . n 
B 1 445 LEU 445 445 ?   ?   ?   B . n 
B 1 446 TYR 446 446 ?   ?   ?   B . n 
B 1 447 PHE 447 447 ?   ?   ?   B . n 
B 1 448 GLN 448 448 ?   ?   ?   B . n 
B 1 449 GLY 449 449 ?   ?   ?   B . n 
B 1 450 HIS 450 450 ?   ?   ?   B . n 
B 1 451 HIS 451 451 ?   ?   ?   B . n 
B 1 452 HIS 452 452 ?   ?   ?   B . n 
B 1 453 HIS 453 453 ?   ?   ?   B . n 
B 1 454 HIS 454 454 ?   ?   ?   B . n 
B 1 455 HIS 455 455 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   ASP 2   2   ?   ?   ?   C . n 
C 1 3   ASN 3   3   ?   ?   ?   C . n 
C 1 4   GLN 4   4   ?   ?   ?   C . n 
C 1 5   LYS 5   5   ?   ?   ?   C . n 
C 1 6   GLY 6   6   ?   ?   ?   C . n 
C 1 7   ARG 7   7   ?   ?   ?   C . n 
C 1 8   ILE 8   8   8   ILE ILE C . n 
C 1 9   SER 9   9   9   SER SER C . n 
C 1 10  ILE 10  10  10  ILE ILE C . n 
C 1 11  ALA 11  11  11  ALA ALA C . n 
C 1 12  LEU 12  12  12  LEU LEU C . n 
C 1 13  LEU 13  13  13  LEU LEU C . n 
C 1 14  PRO 14  14  14  PRO PRO C . n 
C 1 15  PHE 15  15  15  PHE PHE C . n 
C 1 16  LEU 16  16  16  LEU LEU C . n 
C 1 17  ALA 17  17  17  ALA ALA C . n 
C 1 18  HIS 18  18  18  HIS HIS C . n 
C 1 19  GLY 19  19  19  GLY GLY C . n 
C 1 20  HIS 20  20  20  HIS HIS C . n 
C 1 21  ILE 21  21  21  ILE ILE C . n 
C 1 22  SER 22  22  22  SER SER C . n 
C 1 23  PRO 23  23  23  PRO PRO C . n 
C 1 24  PHE 24  24  24  PHE PHE C . n 
C 1 25  PHE 25  25  25  PHE PHE C . n 
C 1 26  GLU 26  26  26  GLU GLU C . n 
C 1 27  LEU 27  27  27  LEU LEU C . n 
C 1 28  ALA 28  28  28  ALA ALA C . n 
C 1 29  LYS 29  29  29  LYS LYS C . n 
C 1 30  GLN 30  30  30  GLN GLN C . n 
C 1 31  LEU 31  31  31  LEU LEU C . n 
C 1 32  ALA 32  32  32  ALA ALA C . n 
C 1 33  LYS 33  33  33  LYS LYS C . n 
C 1 34  ARG 34  34  34  ARG ARG C . n 
C 1 35  ASN 35  35  35  ASN ASN C . n 
C 1 36  CYS 36  36  36  CYS CYS C . n 
C 1 37  ASN 37  37  37  ASN ASN C . n 
C 1 38  VAL 38  38  38  VAL VAL C . n 
C 1 39  PHE 39  39  39  PHE PHE C . n 
C 1 40  LEU 40  40  40  LEU LEU C . n 
C 1 41  CYS 41  41  41  CYS CYS C . n 
C 1 42  SER 42  42  42  SER SER C . n 
C 1 43  THR 43  43  43  THR THR C . n 
C 1 44  PRO 44  44  44  PRO PRO C . n 
C 1 45  ILE 45  45  45  ILE ILE C . n 
C 1 46  ASN 46  46  46  ASN ASN C . n 
C 1 47  LEU 47  47  47  LEU LEU C . n 
C 1 48  SER 48  48  48  SER SER C . n 
C 1 49  SER 49  49  49  SER SER C . n 
C 1 50  ILE 50  50  50  ILE ILE C . n 
C 1 51  LYS 51  51  51  LYS LYS C . n 
C 1 52  ASP 52  52  52  ASP ASP C . n 
C 1 53  LYS 53  53  53  LYS LYS C . n 
C 1 54  ASP 54  54  54  ASP ASP C . n 
C 1 55  SER 55  55  55  SER SER C . n 
C 1 56  SER 56  56  56  SER SER C . n 
C 1 57  ALA 57  57  57  ALA ALA C . n 
C 1 58  SER 58  58  58  SER SER C . n 
C 1 59  ILE 59  59  59  ILE ILE C . n 
C 1 60  LYS 60  60  60  LYS LYS C . n 
C 1 61  LEU 61  61  61  LEU LEU C . n 
C 1 62  VAL 62  62  62  VAL VAL C . n 
C 1 63  GLU 63  63  63  GLU GLU C . n 
C 1 64  LEU 64  64  64  LEU LEU C . n 
C 1 65  HIS 65  65  65  HIS HIS C . n 
C 1 66  LEU 66  66  ?   ?   ?   C . n 
C 1 67  PRO 67  67  ?   ?   ?   C . n 
C 1 68  SER 68  68  ?   ?   ?   C . n 
C 1 69  SER 69  69  ?   ?   ?   C . n 
C 1 70  PRO 70  70  ?   ?   ?   C . n 
C 1 71  ASP 71  71  ?   ?   ?   C . n 
C 1 72  LEU 72  72  ?   ?   ?   C . n 
C 1 73  PRO 73  73  ?   ?   ?   C . n 
C 1 74  PRO 74  74  ?   ?   ?   C . n 
C 1 75  HIS 75  75  ?   ?   ?   C . n 
C 1 76  TYR 76  76  ?   ?   ?   C . n 
C 1 77  HIS 77  77  ?   ?   ?   C . n 
C 1 78  THR 78  78  ?   ?   ?   C . n 
C 1 79  THR 79  79  ?   ?   ?   C . n 
C 1 80  ASN 80  80  ?   ?   ?   C . n 
C 1 81  GLY 81  81  ?   ?   ?   C . n 
C 1 82  LEU 82  82  ?   ?   ?   C . n 
C 1 83  PRO 83  83  ?   ?   ?   C . n 
C 1 84  SER 84  84  ?   ?   ?   C . n 
C 1 85  HIS 85  85  ?   ?   ?   C . n 
C 1 86  LEU 86  86  ?   ?   ?   C . n 
C 1 87  MET 87  87  ?   ?   ?   C . n 
C 1 88  LEU 88  88  ?   ?   ?   C . n 
C 1 89  PRO 89  89  ?   ?   ?   C . n 
C 1 90  LEU 90  90  ?   ?   ?   C . n 
C 1 91  ARG 91  91  91  ARG ARG C . n 
C 1 92  ASN 92  92  92  ASN ASN C . n 
C 1 93  ALA 93  93  93  ALA ALA C . n 
C 1 94  PHE 94  94  94  PHE PHE C . n 
C 1 95  GLU 95  95  95  GLU GLU C . n 
C 1 96  THR 96  96  96  THR THR C . n 
C 1 97  ALA 97  97  97  ALA ALA C . n 
C 1 98  GLY 98  98  98  GLY GLY C . n 
C 1 99  PRO 99  99  99  PRO PRO C . n 
C 1 100 THR 100 100 100 THR THR C . n 
C 1 101 PHE 101 101 101 PHE PHE C . n 
C 1 102 SER 102 102 102 SER SER C . n 
C 1 103 GLU 103 103 103 GLU GLU C . n 
C 1 104 ILE 104 104 104 ILE ILE C . n 
C 1 105 LEU 105 105 105 LEU LEU C . n 
C 1 106 LYS 106 106 106 LYS LYS C . n 
C 1 107 THR 107 107 107 THR THR C . n 
C 1 108 LEU 108 108 108 LEU LEU C . n 
C 1 109 ASN 109 109 109 ASN ASN C . n 
C 1 110 PRO 110 110 110 PRO PRO C . n 
C 1 111 ASP 111 111 111 ASP ASP C . n 
C 1 112 LEU 112 112 112 LEU LEU C . n 
C 1 113 LEU 113 113 113 LEU LEU C . n 
C 1 114 ILE 114 114 114 ILE ILE C . n 
C 1 115 TYR 115 115 115 TYR TYR C . n 
C 1 116 ASP 116 116 116 ASP ASP C . n 
C 1 117 PHE 117 117 117 PHE PHE C . n 
C 1 118 ASN 118 118 118 ASN ASN C . n 
C 1 119 PRO 119 119 119 PRO PRO C . n 
C 1 120 SER 120 120 120 SER SER C . n 
C 1 121 TRP 121 121 121 TRP TRP C . n 
C 1 122 ALA 122 122 122 ALA ALA C . n 
C 1 123 PRO 123 123 123 PRO PRO C . n 
C 1 124 GLU 124 124 124 GLU GLU C . n 
C 1 125 ILE 125 125 125 ILE ILE C . n 
C 1 126 ALA 126 126 126 ALA ALA C . n 
C 1 127 SER 127 127 127 SER SER C . n 
C 1 128 SER 128 128 128 SER SER C . n 
C 1 129 HIS 129 129 129 HIS HIS C . n 
C 1 130 ASN 130 130 130 ASN ASN C . n 
C 1 131 ILE 131 131 131 ILE ILE C . n 
C 1 132 PRO 132 132 132 PRO PRO C . n 
C 1 133 ALA 133 133 133 ALA ALA C . n 
C 1 134 VAL 134 134 134 VAL VAL C . n 
C 1 135 TYR 135 135 135 TYR TYR C . n 
C 1 136 PHE 136 136 136 PHE PHE C . n 
C 1 137 LEU 137 137 137 LEU LEU C . n 
C 1 138 THR 138 138 138 THR THR C . n 
C 1 139 THR 139 139 139 THR THR C . n 
C 1 140 ALA 140 140 140 ALA ALA C . n 
C 1 141 ALA 141 141 141 ALA ALA C . n 
C 1 142 ALA 142 142 142 ALA ALA C . n 
C 1 143 SER 143 143 143 SER SER C . n 
C 1 144 SER 144 144 144 SER SER C . n 
C 1 145 SER 145 145 145 SER SER C . n 
C 1 146 ILE 146 146 146 ILE ILE C . n 
C 1 147 GLY 147 147 147 GLY GLY C . n 
C 1 148 LEU 148 148 148 LEU LEU C . n 
C 1 149 HIS 149 149 149 HIS HIS C . n 
C 1 150 ALA 150 150 150 ALA ALA C . n 
C 1 151 PHE 151 151 151 PHE PHE C . n 
C 1 152 LYS 152 152 152 LYS LYS C . n 
C 1 153 ASN 153 153 153 ASN ASN C . n 
C 1 154 PRO 154 154 154 PRO PRO C . n 
C 1 155 GLY 155 155 155 GLY GLY C . n 
C 1 156 GLU 156 156 156 GLU GLU C . n 
C 1 157 LYS 157 157 157 LYS LYS C . n 
C 1 158 TYR 158 158 158 TYR TYR C . n 
C 1 159 PRO 159 159 159 PRO PRO C . n 
C 1 160 PHE 160 160 160 PHE PHE C . n 
C 1 161 PRO 161 161 161 PRO PRO C . n 
C 1 162 ASP 162 162 162 ASP ASP C . n 
C 1 163 PHE 163 163 163 PHE PHE C . n 
C 1 164 TYR 164 164 164 TYR TYR C . n 
C 1 165 ASP 165 165 165 ASP ASP C . n 
C 1 166 ASN 166 166 166 ASN ASN C . n 
C 1 167 SER 167 167 167 SER SER C . n 
C 1 168 ASN 168 168 ?   ?   ?   C . n 
C 1 169 ILE 169 169 ?   ?   ?   C . n 
C 1 170 ILE 170 170 ?   ?   ?   C . n 
C 1 171 PRO 171 171 ?   ?   ?   C . n 
C 1 172 GLU 172 172 ?   ?   ?   C . n 
C 1 173 PRO 173 173 ?   ?   ?   C . n 
C 1 174 PRO 174 174 ?   ?   ?   C . n 
C 1 175 SER 175 175 ?   ?   ?   C . n 
C 1 176 ALA 176 176 ?   ?   ?   C . n 
C 1 177 ASP 177 177 ?   ?   ?   C . n 
C 1 178 ASN 178 178 178 ASN ASN C . n 
C 1 179 MET 179 179 179 MET MET C . n 
C 1 180 LYS 180 180 180 LYS LYS C . n 
C 1 181 LEU 181 181 181 LEU LEU C . n 
C 1 182 LEU 182 182 182 LEU LEU C . n 
C 1 183 HIS 183 183 183 HIS HIS C . n 
C 1 184 ASP 184 184 184 ASP ASP C . n 
C 1 185 PHE 185 185 185 PHE PHE C . n 
C 1 186 ILE 186 186 186 ILE ILE C . n 
C 1 187 ALA 187 187 187 ALA ALA C . n 
C 1 188 CYS 188 188 188 CYS CYS C . n 
C 1 189 PHE 189 189 189 PHE PHE C . n 
C 1 190 GLU 190 190 190 GLU GLU C . n 
C 1 191 ARG 191 191 191 ARG ARG C . n 
C 1 192 SER 192 192 192 SER SER C . n 
C 1 193 CYS 193 193 193 CYS CYS C . n 
C 1 194 ASP 194 194 194 ASP ASP C . n 
C 1 195 ILE 195 195 195 ILE ILE C . n 
C 1 196 ILE 196 196 196 ILE ILE C . n 
C 1 197 LEU 197 197 197 LEU LEU C . n 
C 1 198 ILE 198 198 198 ILE ILE C . n 
C 1 199 LYS 199 199 199 LYS LYS C . n 
C 1 200 SER 200 200 200 SER SER C . n 
C 1 201 PHE 201 201 201 PHE PHE C . n 
C 1 202 ARG 202 202 202 ARG ARG C . n 
C 1 203 GLU 203 203 203 GLU GLU C . n 
C 1 204 LEU 204 204 204 LEU LEU C . n 
C 1 205 GLU 205 205 205 GLU GLU C . n 
C 1 206 GLY 206 206 206 GLY GLY C . n 
C 1 207 LYS 207 207 207 LYS LYS C . n 
C 1 208 TYR 208 208 208 TYR TYR C . n 
C 1 209 ILE 209 209 209 ILE ILE C . n 
C 1 210 ASP 210 210 210 ASP ASP C . n 
C 1 211 LEU 211 211 211 LEU LEU C . n 
C 1 212 LEU 212 212 212 LEU LEU C . n 
C 1 213 SER 213 213 213 SER SER C . n 
C 1 214 THR 214 214 214 THR THR C . n 
C 1 215 LEU 215 215 215 LEU LEU C . n 
C 1 216 SER 216 216 216 SER SER C . n 
C 1 217 ASP 217 217 217 ASP ASP C . n 
C 1 218 LYS 218 218 218 LYS LYS C . n 
C 1 219 THR 219 219 219 THR THR C . n 
C 1 220 LEU 220 220 220 LEU LEU C . n 
C 1 221 VAL 221 221 221 VAL VAL C . n 
C 1 222 PRO 222 222 222 PRO PRO C . n 
C 1 223 VAL 223 223 223 VAL VAL C . n 
C 1 224 GLY 224 224 224 GLY GLY C . n 
C 1 225 PRO 225 225 225 PRO PRO C . n 
C 1 226 LEU 226 226 226 LEU LEU C . n 
C 1 227 VAL 227 227 227 VAL VAL C . n 
C 1 228 GLN 228 228 ?   ?   ?   C . n 
C 1 229 ASP 229 229 ?   ?   ?   C . n 
C 1 230 PRO 230 230 ?   ?   ?   C . n 
C 1 231 MET 231 231 ?   ?   ?   C . n 
C 1 232 GLY 232 232 ?   ?   ?   C . n 
C 1 233 HIS 233 233 ?   ?   ?   C . n 
C 1 234 ASN 234 234 ?   ?   ?   C . n 
C 1 235 GLU 235 235 ?   ?   ?   C . n 
C 1 236 ASP 236 236 236 ASP ASP C . n 
C 1 237 PRO 237 237 237 PRO PRO C . n 
C 1 238 LYS 238 238 238 LYS LYS C . n 
C 1 239 THR 239 239 239 THR THR C . n 
C 1 240 GLU 240 240 240 GLU GLU C . n 
C 1 241 GLN 241 241 241 GLN GLN C . n 
C 1 242 ILE 242 242 242 ILE ILE C . n 
C 1 243 ILE 243 243 243 ILE ILE C . n 
C 1 244 ASN 244 244 244 ASN ASN C . n 
C 1 245 TRP 245 245 245 TRP TRP C . n 
C 1 246 LEU 246 246 246 LEU LEU C . n 
C 1 247 ASP 247 247 247 ASP ASP C . n 
C 1 248 LYS 248 248 248 LYS LYS C . n 
C 1 249 ARG 249 249 249 ARG ARG C . n 
C 1 250 ALA 250 250 250 ALA ALA C . n 
C 1 251 GLU 251 251 251 GLU GLU C . n 
C 1 252 SER 252 252 252 SER SER C . n 
C 1 253 THR 253 253 253 THR THR C . n 
C 1 254 VAL 254 254 254 VAL VAL C . n 
C 1 255 VAL 255 255 255 VAL VAL C . n 
C 1 256 PHE 256 256 256 PHE PHE C . n 
C 1 257 VAL 257 257 257 VAL VAL C . n 
C 1 258 CYS 258 258 258 CYS CYS C . n 
C 1 259 PHE 259 259 259 PHE PHE C . n 
C 1 260 GLY 260 260 260 GLY GLY C . n 
C 1 261 SER 261 261 261 SER SER C . n 
C 1 262 GLU 262 262 262 GLU GLU C . n 
C 1 263 TYR 263 263 263 TYR TYR C . n 
C 1 264 PHE 264 264 264 PHE PHE C . n 
C 1 265 LEU 265 265 265 LEU LEU C . n 
C 1 266 SER 266 266 266 SER SER C . n 
C 1 267 ASN 267 267 267 ASN ASN C . n 
C 1 268 GLU 268 268 268 GLU GLU C . n 
C 1 269 GLU 269 269 269 GLU GLU C . n 
C 1 270 LEU 270 270 270 LEU LEU C . n 
C 1 271 GLU 271 271 271 GLU GLU C . n 
C 1 272 GLU 272 272 272 GLU GLU C . n 
C 1 273 VAL 273 273 273 VAL VAL C . n 
C 1 274 ALA 274 274 274 ALA ALA C . n 
C 1 275 ILE 275 275 275 ILE ILE C . n 
C 1 276 GLY 276 276 276 GLY GLY C . n 
C 1 277 LEU 277 277 277 LEU LEU C . n 
C 1 278 GLU 278 278 278 GLU GLU C . n 
C 1 279 ILE 279 279 279 ILE ILE C . n 
C 1 280 SER 280 280 280 SER SER C . n 
C 1 281 THR 281 281 281 THR THR C . n 
C 1 282 VAL 282 282 282 VAL VAL C . n 
C 1 283 ASN 283 283 283 ASN ASN C . n 
C 1 284 PHE 284 284 284 PHE PHE C . n 
C 1 285 ILE 285 285 285 ILE ILE C . n 
C 1 286 TRP 286 286 286 TRP TRP C . n 
C 1 287 ALA 287 287 287 ALA ALA C . n 
C 1 288 VAL 288 288 288 VAL VAL C . n 
C 1 289 ARG 289 289 ?   ?   ?   C . n 
C 1 290 LEU 290 290 ?   ?   ?   C . n 
C 1 291 ILE 291 291 ?   ?   ?   C . n 
C 1 292 GLU 292 292 ?   ?   ?   C . n 
C 1 293 GLY 293 293 ?   ?   ?   C . n 
C 1 294 GLU 294 294 ?   ?   ?   C . n 
C 1 295 LYS 295 295 ?   ?   ?   C . n 
C 1 296 LYS 296 296 ?   ?   ?   C . n 
C 1 297 GLY 297 297 ?   ?   ?   C . n 
C 1 298 ILE 298 298 ?   ?   ?   C . n 
C 1 299 LEU 299 299 ?   ?   ?   C . n 
C 1 300 PRO 300 300 ?   ?   ?   C . n 
C 1 301 GLU 301 301 ?   ?   ?   C . n 
C 1 302 GLY 302 302 ?   ?   ?   C . n 
C 1 303 PHE 303 303 303 PHE PHE C . n 
C 1 304 VAL 304 304 304 VAL VAL C . n 
C 1 305 GLN 305 305 305 GLN GLN C . n 
C 1 306 ARG 306 306 306 ARG ARG C . n 
C 1 307 VAL 307 307 307 VAL VAL C . n 
C 1 308 GLY 308 308 308 GLY GLY C . n 
C 1 309 ASP 309 309 309 ASP ASP C . n 
C 1 310 ARG 310 310 310 ARG ARG C . n 
C 1 311 GLY 311 311 311 GLY GLY C . n 
C 1 312 LEU 312 312 312 LEU LEU C . n 
C 1 313 VAL 313 313 313 VAL VAL C . n 
C 1 314 VAL 314 314 314 VAL VAL C . n 
C 1 315 GLU 315 315 315 GLU GLU C . n 
C 1 316 GLY 316 316 316 GLY GLY C . n 
C 1 317 TRP 317 317 317 TRP TRP C . n 
C 1 318 ALA 318 318 318 ALA ALA C . n 
C 1 319 PRO 319 319 319 PRO PRO C . n 
C 1 320 GLN 320 320 320 GLN GLN C . n 
C 1 321 ALA 321 321 321 ALA ALA C . n 
C 1 322 ARG 322 322 322 ARG ARG C . n 
C 1 323 ILE 323 323 323 ILE ILE C . n 
C 1 324 LEU 324 324 324 LEU LEU C . n 
C 1 325 GLY 325 325 325 GLY GLY C . n 
C 1 326 HIS 326 326 326 HIS HIS C . n 
C 1 327 SER 327 327 327 SER SER C . n 
C 1 328 SER 328 328 328 SER SER C . n 
C 1 329 THR 329 329 329 THR THR C . n 
C 1 330 GLY 330 330 330 GLY GLY C . n 
C 1 331 GLY 331 331 331 GLY GLY C . n 
C 1 332 PHE 332 332 332 PHE PHE C . n 
C 1 333 VAL 333 333 333 VAL VAL C . n 
C 1 334 SER 334 334 334 SER SER C . n 
C 1 335 HIS 335 335 335 HIS HIS C . n 
C 1 336 CYS 336 336 336 CYS CYS C . n 
C 1 337 GLY 337 337 337 GLY GLY C . n 
C 1 338 TRP 338 338 338 TRP TRP C . n 
C 1 339 SER 339 339 339 SER SER C . n 
C 1 340 SER 340 340 340 SER SER C . n 
C 1 341 ILE 341 341 341 ILE ILE C . n 
C 1 342 ALA 342 342 342 ALA ALA C . n 
C 1 343 GLU 343 343 343 GLU GLU C . n 
C 1 344 SER 344 344 344 SER SER C . n 
C 1 345 MET 345 345 345 MET MET C . n 
C 1 346 LYS 346 346 346 LYS LYS C . n 
C 1 347 PHE 347 347 347 PHE PHE C . n 
C 1 348 GLY 348 348 348 GLY GLY C . n 
C 1 349 VAL 349 349 349 VAL VAL C . n 
C 1 350 PRO 350 350 350 PRO PRO C . n 
C 1 351 VAL 351 351 351 VAL VAL C . n 
C 1 352 ILE 352 352 352 ILE ILE C . n 
C 1 353 ALA 353 353 353 ALA ALA C . n 
C 1 354 MET 354 354 354 MET MET C . n 
C 1 355 ALA 355 355 355 ALA ALA C . n 
C 1 356 ARG 356 356 356 ARG ARG C . n 
C 1 357 HIS 357 357 357 HIS HIS C . n 
C 1 358 LEU 358 358 358 LEU LEU C . n 
C 1 359 ASP 359 359 359 ASP ASP C . n 
C 1 360 GLN 360 360 360 GLN GLN C . n 
C 1 361 PRO 361 361 361 PRO PRO C . n 
C 1 362 LEU 362 362 362 LEU LEU C . n 
C 1 363 ASN 363 363 363 ASN ASN C . n 
C 1 364 GLY 364 364 364 GLY GLY C . n 
C 1 365 LYS 365 365 365 LYS LYS C . n 
C 1 366 LEU 366 366 366 LEU LEU C . n 
C 1 367 ALA 367 367 367 ALA ALA C . n 
C 1 368 ALA 368 368 368 ALA ALA C . n 
C 1 369 GLU 369 369 369 GLU GLU C . n 
C 1 370 VAL 370 370 370 VAL VAL C . n 
C 1 371 GLY 371 371 371 GLY GLY C . n 
C 1 372 VAL 372 372 372 VAL VAL C . n 
C 1 373 GLY 373 373 373 GLY GLY C . n 
C 1 374 MET 374 374 374 MET MET C . n 
C 1 375 GLU 375 375 375 GLU GLU C . n 
C 1 376 VAL 376 376 376 VAL VAL C . n 
C 1 377 VAL 377 377 377 VAL VAL C . n 
C 1 378 ARG 378 378 378 ARG ARG C . n 
C 1 379 ASP 379 379 379 ASP ASP C . n 
C 1 380 GLU 380 380 380 GLU GLU C . n 
C 1 381 ASN 381 381 381 ASN ASN C . n 
C 1 382 GLY 382 382 382 GLY GLY C . n 
C 1 383 LYS 383 383 383 LYS LYS C . n 
C 1 384 TYR 384 384 384 TYR TYR C . n 
C 1 385 LYS 385 385 385 LYS LYS C . n 
C 1 386 ARG 386 386 386 ARG ARG C . n 
C 1 387 GLU 387 387 387 GLU GLU C . n 
C 1 388 GLY 388 388 388 GLY GLY C . n 
C 1 389 ILE 389 389 389 ILE ILE C . n 
C 1 390 ALA 390 390 390 ALA ALA C . n 
C 1 391 GLU 391 391 391 GLU GLU C . n 
C 1 392 VAL 392 392 392 VAL VAL C . n 
C 1 393 ILE 393 393 393 ILE ILE C . n 
C 1 394 ARG 394 394 394 ARG ARG C . n 
C 1 395 LYS 395 395 395 LYS LYS C . n 
C 1 396 VAL 396 396 396 VAL VAL C . n 
C 1 397 VAL 397 397 397 VAL VAL C . n 
C 1 398 VAL 398 398 398 VAL VAL C . n 
C 1 399 GLU 399 399 399 GLU GLU C . n 
C 1 400 LYS 400 400 400 LYS LYS C . n 
C 1 401 SER 401 401 401 SER SER C . n 
C 1 402 GLY 402 402 402 GLY GLY C . n 
C 1 403 GLU 403 403 403 GLU GLU C . n 
C 1 404 VAL 404 404 404 VAL VAL C . n 
C 1 405 ILE 405 405 405 ILE ILE C . n 
C 1 406 ARG 406 406 406 ARG ARG C . n 
C 1 407 ARG 407 407 407 ARG ARG C . n 
C 1 408 LYS 408 408 408 LYS LYS C . n 
C 1 409 ALA 409 409 409 ALA ALA C . n 
C 1 410 ARG 410 410 410 ARG ARG C . n 
C 1 411 GLU 411 411 411 GLU GLU C . n 
C 1 412 LEU 412 412 412 LEU LEU C . n 
C 1 413 SER 413 413 413 SER SER C . n 
C 1 414 GLU 414 414 414 GLU GLU C . n 
C 1 415 LYS 415 415 415 LYS LYS C . n 
C 1 416 MET 416 416 416 MET MET C . n 
C 1 417 LYS 417 417 417 LYS LYS C . n 
C 1 418 GLU 418 418 418 GLU GLU C . n 
C 1 419 LYS 419 419 419 LYS LYS C . n 
C 1 420 GLY 420 420 420 GLY GLY C . n 
C 1 421 GLU 421 421 421 GLU GLU C . n 
C 1 422 GLN 422 422 422 GLN GLN C . n 
C 1 423 GLU 423 423 423 GLU GLU C . n 
C 1 424 ILE 424 424 424 ILE ILE C . n 
C 1 425 ASP 425 425 425 ASP ASP C . n 
C 1 426 ARG 426 426 426 ARG ARG C . n 
C 1 427 ALA 427 427 427 ALA ALA C . n 
C 1 428 VAL 428 428 428 VAL VAL C . n 
C 1 429 GLU 429 429 429 GLU GLU C . n 
C 1 430 GLU 430 430 430 GLU GLU C . n 
C 1 431 LEU 431 431 431 LEU LEU C . n 
C 1 432 VAL 432 432 432 VAL VAL C . n 
C 1 433 GLN 433 433 433 GLN GLN C . n 
C 1 434 ILE 434 434 434 ILE ILE C . n 
C 1 435 CYS 435 435 435 CYS CYS C . n 
C 1 436 LYS 436 436 436 LYS LYS C . n 
C 1 437 LYS 437 437 437 LYS LYS C . n 
C 1 438 LYS 438 438 438 LYS LYS C . n 
C 1 439 LYS 439 439 439 LYS LYS C . n 
C 1 440 ASP 440 440 440 ASP ASP C . n 
C 1 441 GLU 441 441 441 GLU GLU C . n 
C 1 442 GLN 442 442 442 GLN GLN C . n 
C 1 443 GLU 443 443 ?   ?   ?   C . n 
C 1 444 ASN 444 444 ?   ?   ?   C . n 
C 1 445 LEU 445 445 ?   ?   ?   C . n 
C 1 446 TYR 446 446 ?   ?   ?   C . n 
C 1 447 PHE 447 447 ?   ?   ?   C . n 
C 1 448 GLN 448 448 ?   ?   ?   C . n 
C 1 449 GLY 449 449 ?   ?   ?   C . n 
C 1 450 HIS 450 450 ?   ?   ?   C . n 
C 1 451 HIS 451 451 ?   ?   ?   C . n 
C 1 452 HIS 452 452 ?   ?   ?   C . n 
C 1 453 HIS 453 453 ?   ?   ?   C . n 
C 1 454 HIS 454 454 ?   ?   ?   C . n 
C 1 455 HIS 455 455 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   ASP 2   2   ?   ?   ?   D . n 
D 1 3   ASN 3   3   ?   ?   ?   D . n 
D 1 4   GLN 4   4   ?   ?   ?   D . n 
D 1 5   LYS 5   5   ?   ?   ?   D . n 
D 1 6   GLY 6   6   ?   ?   ?   D . n 
D 1 7   ARG 7   7   ?   ?   ?   D . n 
D 1 8   ILE 8   8   8   ILE ILE D . n 
D 1 9   SER 9   9   9   SER SER D . n 
D 1 10  ILE 10  10  10  ILE ILE D . n 
D 1 11  ALA 11  11  11  ALA ALA D . n 
D 1 12  LEU 12  12  12  LEU LEU D . n 
D 1 13  LEU 13  13  13  LEU LEU D . n 
D 1 14  PRO 14  14  14  PRO PRO D . n 
D 1 15  PHE 15  15  15  PHE PHE D . n 
D 1 16  LEU 16  16  16  LEU LEU D . n 
D 1 17  ALA 17  17  17  ALA ALA D . n 
D 1 18  HIS 18  18  18  HIS HIS D . n 
D 1 19  GLY 19  19  19  GLY GLY D . n 
D 1 20  HIS 20  20  20  HIS HIS D . n 
D 1 21  ILE 21  21  21  ILE ILE D . n 
D 1 22  SER 22  22  22  SER SER D . n 
D 1 23  PRO 23  23  23  PRO PRO D . n 
D 1 24  PHE 24  24  24  PHE PHE D . n 
D 1 25  PHE 25  25  25  PHE PHE D . n 
D 1 26  GLU 26  26  26  GLU GLU D . n 
D 1 27  LEU 27  27  27  LEU LEU D . n 
D 1 28  ALA 28  28  28  ALA ALA D . n 
D 1 29  LYS 29  29  29  LYS LYS D . n 
D 1 30  GLN 30  30  30  GLN GLN D . n 
D 1 31  LEU 31  31  31  LEU LEU D . n 
D 1 32  ALA 32  32  32  ALA ALA D . n 
D 1 33  LYS 33  33  33  LYS LYS D . n 
D 1 34  ARG 34  34  34  ARG ARG D . n 
D 1 35  ASN 35  35  35  ASN ASN D . n 
D 1 36  CYS 36  36  36  CYS CYS D . n 
D 1 37  ASN 37  37  37  ASN ASN D . n 
D 1 38  VAL 38  38  38  VAL VAL D . n 
D 1 39  PHE 39  39  39  PHE PHE D . n 
D 1 40  LEU 40  40  40  LEU LEU D . n 
D 1 41  CYS 41  41  41  CYS CYS D . n 
D 1 42  SER 42  42  42  SER SER D . n 
D 1 43  THR 43  43  43  THR THR D . n 
D 1 44  PRO 44  44  44  PRO PRO D . n 
D 1 45  ILE 45  45  45  ILE ILE D . n 
D 1 46  ASN 46  46  46  ASN ASN D . n 
D 1 47  LEU 47  47  47  LEU LEU D . n 
D 1 48  SER 48  48  48  SER SER D . n 
D 1 49  SER 49  49  49  SER SER D . n 
D 1 50  ILE 50  50  50  ILE ILE D . n 
D 1 51  LYS 51  51  51  LYS LYS D . n 
D 1 52  ASP 52  52  52  ASP ASP D . n 
D 1 53  LYS 53  53  53  LYS LYS D . n 
D 1 54  ASP 54  54  54  ASP ASP D . n 
D 1 55  SER 55  55  55  SER SER D . n 
D 1 56  SER 56  56  56  SER SER D . n 
D 1 57  ALA 57  57  57  ALA ALA D . n 
D 1 58  SER 58  58  58  SER SER D . n 
D 1 59  ILE 59  59  59  ILE ILE D . n 
D 1 60  LYS 60  60  60  LYS LYS D . n 
D 1 61  LEU 61  61  61  LEU LEU D . n 
D 1 62  VAL 62  62  62  VAL VAL D . n 
D 1 63  GLU 63  63  63  GLU GLU D . n 
D 1 64  LEU 64  64  64  LEU LEU D . n 
D 1 65  HIS 65  65  65  HIS HIS D . n 
D 1 66  LEU 66  66  ?   ?   ?   D . n 
D 1 67  PRO 67  67  ?   ?   ?   D . n 
D 1 68  SER 68  68  ?   ?   ?   D . n 
D 1 69  SER 69  69  ?   ?   ?   D . n 
D 1 70  PRO 70  70  ?   ?   ?   D . n 
D 1 71  ASP 71  71  ?   ?   ?   D . n 
D 1 72  LEU 72  72  ?   ?   ?   D . n 
D 1 73  PRO 73  73  ?   ?   ?   D . n 
D 1 74  PRO 74  74  ?   ?   ?   D . n 
D 1 75  HIS 75  75  ?   ?   ?   D . n 
D 1 76  TYR 76  76  ?   ?   ?   D . n 
D 1 77  HIS 77  77  ?   ?   ?   D . n 
D 1 78  THR 78  78  ?   ?   ?   D . n 
D 1 79  THR 79  79  ?   ?   ?   D . n 
D 1 80  ASN 80  80  ?   ?   ?   D . n 
D 1 81  GLY 81  81  ?   ?   ?   D . n 
D 1 82  LEU 82  82  ?   ?   ?   D . n 
D 1 83  PRO 83  83  ?   ?   ?   D . n 
D 1 84  SER 84  84  ?   ?   ?   D . n 
D 1 85  HIS 85  85  ?   ?   ?   D . n 
D 1 86  LEU 86  86  ?   ?   ?   D . n 
D 1 87  MET 87  87  ?   ?   ?   D . n 
D 1 88  LEU 88  88  ?   ?   ?   D . n 
D 1 89  PRO 89  89  ?   ?   ?   D . n 
D 1 90  LEU 90  90  ?   ?   ?   D . n 
D 1 91  ARG 91  91  91  ARG ARG D . n 
D 1 92  ASN 92  92  92  ASN ASN D . n 
D 1 93  ALA 93  93  93  ALA ALA D . n 
D 1 94  PHE 94  94  94  PHE PHE D . n 
D 1 95  GLU 95  95  95  GLU GLU D . n 
D 1 96  THR 96  96  96  THR THR D . n 
D 1 97  ALA 97  97  97  ALA ALA D . n 
D 1 98  GLY 98  98  98  GLY GLY D . n 
D 1 99  PRO 99  99  99  PRO PRO D . n 
D 1 100 THR 100 100 100 THR THR D . n 
D 1 101 PHE 101 101 101 PHE PHE D . n 
D 1 102 SER 102 102 102 SER SER D . n 
D 1 103 GLU 103 103 103 GLU GLU D . n 
D 1 104 ILE 104 104 104 ILE ILE D . n 
D 1 105 LEU 105 105 105 LEU LEU D . n 
D 1 106 LYS 106 106 106 LYS LYS D . n 
D 1 107 THR 107 107 107 THR THR D . n 
D 1 108 LEU 108 108 108 LEU LEU D . n 
D 1 109 ASN 109 109 109 ASN ASN D . n 
D 1 110 PRO 110 110 110 PRO PRO D . n 
D 1 111 ASP 111 111 111 ASP ASP D . n 
D 1 112 LEU 112 112 112 LEU LEU D . n 
D 1 113 LEU 113 113 113 LEU LEU D . n 
D 1 114 ILE 114 114 114 ILE ILE D . n 
D 1 115 TYR 115 115 115 TYR TYR D . n 
D 1 116 ASP 116 116 116 ASP ASP D . n 
D 1 117 PHE 117 117 117 PHE PHE D . n 
D 1 118 ASN 118 118 118 ASN ASN D . n 
D 1 119 PRO 119 119 119 PRO PRO D . n 
D 1 120 SER 120 120 120 SER SER D . n 
D 1 121 TRP 121 121 121 TRP TRP D . n 
D 1 122 ALA 122 122 122 ALA ALA D . n 
D 1 123 PRO 123 123 123 PRO PRO D . n 
D 1 124 GLU 124 124 124 GLU GLU D . n 
D 1 125 ILE 125 125 125 ILE ILE D . n 
D 1 126 ALA 126 126 126 ALA ALA D . n 
D 1 127 SER 127 127 127 SER SER D . n 
D 1 128 SER 128 128 128 SER SER D . n 
D 1 129 HIS 129 129 129 HIS HIS D . n 
D 1 130 ASN 130 130 130 ASN ASN D . n 
D 1 131 ILE 131 131 131 ILE ILE D . n 
D 1 132 PRO 132 132 132 PRO PRO D . n 
D 1 133 ALA 133 133 133 ALA ALA D . n 
D 1 134 VAL 134 134 134 VAL VAL D . n 
D 1 135 TYR 135 135 135 TYR TYR D . n 
D 1 136 PHE 136 136 136 PHE PHE D . n 
D 1 137 LEU 137 137 137 LEU LEU D . n 
D 1 138 THR 138 138 138 THR THR D . n 
D 1 139 THR 139 139 139 THR THR D . n 
D 1 140 ALA 140 140 140 ALA ALA D . n 
D 1 141 ALA 141 141 141 ALA ALA D . n 
D 1 142 ALA 142 142 142 ALA ALA D . n 
D 1 143 SER 143 143 143 SER SER D . n 
D 1 144 SER 144 144 144 SER SER D . n 
D 1 145 SER 145 145 145 SER SER D . n 
D 1 146 ILE 146 146 146 ILE ILE D . n 
D 1 147 GLY 147 147 147 GLY GLY D . n 
D 1 148 LEU 148 148 148 LEU LEU D . n 
D 1 149 HIS 149 149 149 HIS HIS D . n 
D 1 150 ALA 150 150 150 ALA ALA D . n 
D 1 151 PHE 151 151 151 PHE PHE D . n 
D 1 152 LYS 152 152 152 LYS LYS D . n 
D 1 153 ASN 153 153 153 ASN ASN D . n 
D 1 154 PRO 154 154 154 PRO PRO D . n 
D 1 155 GLY 155 155 155 GLY GLY D . n 
D 1 156 GLU 156 156 156 GLU GLU D . n 
D 1 157 LYS 157 157 157 LYS LYS D . n 
D 1 158 TYR 158 158 158 TYR TYR D . n 
D 1 159 PRO 159 159 159 PRO PRO D . n 
D 1 160 PHE 160 160 160 PHE PHE D . n 
D 1 161 PRO 161 161 161 PRO PRO D . n 
D 1 162 ASP 162 162 162 ASP ASP D . n 
D 1 163 PHE 163 163 163 PHE PHE D . n 
D 1 164 TYR 164 164 164 TYR TYR D . n 
D 1 165 ASP 165 165 165 ASP ASP D . n 
D 1 166 ASN 166 166 166 ASN ASN D . n 
D 1 167 SER 167 167 167 SER SER D . n 
D 1 168 ASN 168 168 ?   ?   ?   D . n 
D 1 169 ILE 169 169 ?   ?   ?   D . n 
D 1 170 ILE 170 170 ?   ?   ?   D . n 
D 1 171 PRO 171 171 ?   ?   ?   D . n 
D 1 172 GLU 172 172 ?   ?   ?   D . n 
D 1 173 PRO 173 173 ?   ?   ?   D . n 
D 1 174 PRO 174 174 ?   ?   ?   D . n 
D 1 175 SER 175 175 ?   ?   ?   D . n 
D 1 176 ALA 176 176 ?   ?   ?   D . n 
D 1 177 ASP 177 177 ?   ?   ?   D . n 
D 1 178 ASN 178 178 178 ASN ASN D . n 
D 1 179 MET 179 179 179 MET MET D . n 
D 1 180 LYS 180 180 180 LYS LYS D . n 
D 1 181 LEU 181 181 181 LEU LEU D . n 
D 1 182 LEU 182 182 182 LEU LEU D . n 
D 1 183 HIS 183 183 183 HIS HIS D . n 
D 1 184 ASP 184 184 184 ASP ASP D . n 
D 1 185 PHE 185 185 185 PHE PHE D . n 
D 1 186 ILE 186 186 186 ILE ILE D . n 
D 1 187 ALA 187 187 187 ALA ALA D . n 
D 1 188 CYS 188 188 188 CYS CYS D . n 
D 1 189 PHE 189 189 189 PHE PHE D . n 
D 1 190 GLU 190 190 190 GLU GLU D . n 
D 1 191 ARG 191 191 191 ARG ARG D . n 
D 1 192 SER 192 192 192 SER SER D . n 
D 1 193 CYS 193 193 193 CYS CYS D . n 
D 1 194 ASP 194 194 194 ASP ASP D . n 
D 1 195 ILE 195 195 195 ILE ILE D . n 
D 1 196 ILE 196 196 196 ILE ILE D . n 
D 1 197 LEU 197 197 197 LEU LEU D . n 
D 1 198 ILE 198 198 198 ILE ILE D . n 
D 1 199 LYS 199 199 199 LYS LYS D . n 
D 1 200 SER 200 200 200 SER SER D . n 
D 1 201 PHE 201 201 201 PHE PHE D . n 
D 1 202 ARG 202 202 202 ARG ARG D . n 
D 1 203 GLU 203 203 203 GLU GLU D . n 
D 1 204 LEU 204 204 204 LEU LEU D . n 
D 1 205 GLU 205 205 205 GLU GLU D . n 
D 1 206 GLY 206 206 206 GLY GLY D . n 
D 1 207 LYS 207 207 207 LYS LYS D . n 
D 1 208 TYR 208 208 208 TYR TYR D . n 
D 1 209 ILE 209 209 209 ILE ILE D . n 
D 1 210 ASP 210 210 210 ASP ASP D . n 
D 1 211 LEU 211 211 211 LEU LEU D . n 
D 1 212 LEU 212 212 212 LEU LEU D . n 
D 1 213 SER 213 213 213 SER SER D . n 
D 1 214 THR 214 214 214 THR THR D . n 
D 1 215 LEU 215 215 215 LEU LEU D . n 
D 1 216 SER 216 216 216 SER SER D . n 
D 1 217 ASP 217 217 217 ASP ASP D . n 
D 1 218 LYS 218 218 218 LYS LYS D . n 
D 1 219 THR 219 219 219 THR THR D . n 
D 1 220 LEU 220 220 220 LEU LEU D . n 
D 1 221 VAL 221 221 221 VAL VAL D . n 
D 1 222 PRO 222 222 222 PRO PRO D . n 
D 1 223 VAL 223 223 223 VAL VAL D . n 
D 1 224 GLY 224 224 224 GLY GLY D . n 
D 1 225 PRO 225 225 225 PRO PRO D . n 
D 1 226 LEU 226 226 226 LEU LEU D . n 
D 1 227 VAL 227 227 227 VAL VAL D . n 
D 1 228 GLN 228 228 ?   ?   ?   D . n 
D 1 229 ASP 229 229 ?   ?   ?   D . n 
D 1 230 PRO 230 230 ?   ?   ?   D . n 
D 1 231 MET 231 231 ?   ?   ?   D . n 
D 1 232 GLY 232 232 ?   ?   ?   D . n 
D 1 233 HIS 233 233 ?   ?   ?   D . n 
D 1 234 ASN 234 234 ?   ?   ?   D . n 
D 1 235 GLU 235 235 ?   ?   ?   D . n 
D 1 236 ASP 236 236 236 ASP ASP D . n 
D 1 237 PRO 237 237 237 PRO PRO D . n 
D 1 238 LYS 238 238 238 LYS LYS D . n 
D 1 239 THR 239 239 239 THR THR D . n 
D 1 240 GLU 240 240 240 GLU GLU D . n 
D 1 241 GLN 241 241 241 GLN GLN D . n 
D 1 242 ILE 242 242 242 ILE ILE D . n 
D 1 243 ILE 243 243 243 ILE ILE D . n 
D 1 244 ASN 244 244 244 ASN ASN D . n 
D 1 245 TRP 245 245 245 TRP TRP D . n 
D 1 246 LEU 246 246 246 LEU LEU D . n 
D 1 247 ASP 247 247 247 ASP ASP D . n 
D 1 248 LYS 248 248 248 LYS LYS D . n 
D 1 249 ARG 249 249 249 ARG ARG D . n 
D 1 250 ALA 250 250 250 ALA ALA D . n 
D 1 251 GLU 251 251 251 GLU GLU D . n 
D 1 252 SER 252 252 252 SER SER D . n 
D 1 253 THR 253 253 253 THR THR D . n 
D 1 254 VAL 254 254 254 VAL VAL D . n 
D 1 255 VAL 255 255 255 VAL VAL D . n 
D 1 256 PHE 256 256 256 PHE PHE D . n 
D 1 257 VAL 257 257 257 VAL VAL D . n 
D 1 258 CYS 258 258 258 CYS CYS D . n 
D 1 259 PHE 259 259 259 PHE PHE D . n 
D 1 260 GLY 260 260 260 GLY GLY D . n 
D 1 261 SER 261 261 261 SER SER D . n 
D 1 262 GLU 262 262 262 GLU GLU D . n 
D 1 263 TYR 263 263 263 TYR TYR D . n 
D 1 264 PHE 264 264 264 PHE PHE D . n 
D 1 265 LEU 265 265 265 LEU LEU D . n 
D 1 266 SER 266 266 266 SER SER D . n 
D 1 267 ASN 267 267 267 ASN ASN D . n 
D 1 268 GLU 268 268 268 GLU GLU D . n 
D 1 269 GLU 269 269 269 GLU GLU D . n 
D 1 270 LEU 270 270 270 LEU LEU D . n 
D 1 271 GLU 271 271 271 GLU GLU D . n 
D 1 272 GLU 272 272 272 GLU GLU D . n 
D 1 273 VAL 273 273 273 VAL VAL D . n 
D 1 274 ALA 274 274 274 ALA ALA D . n 
D 1 275 ILE 275 275 275 ILE ILE D . n 
D 1 276 GLY 276 276 276 GLY GLY D . n 
D 1 277 LEU 277 277 277 LEU LEU D . n 
D 1 278 GLU 278 278 278 GLU GLU D . n 
D 1 279 ILE 279 279 279 ILE ILE D . n 
D 1 280 SER 280 280 280 SER SER D . n 
D 1 281 THR 281 281 281 THR THR D . n 
D 1 282 VAL 282 282 282 VAL VAL D . n 
D 1 283 ASN 283 283 283 ASN ASN D . n 
D 1 284 PHE 284 284 284 PHE PHE D . n 
D 1 285 ILE 285 285 285 ILE ILE D . n 
D 1 286 TRP 286 286 286 TRP TRP D . n 
D 1 287 ALA 287 287 287 ALA ALA D . n 
D 1 288 VAL 288 288 288 VAL VAL D . n 
D 1 289 ARG 289 289 ?   ?   ?   D . n 
D 1 290 LEU 290 290 ?   ?   ?   D . n 
D 1 291 ILE 291 291 ?   ?   ?   D . n 
D 1 292 GLU 292 292 ?   ?   ?   D . n 
D 1 293 GLY 293 293 ?   ?   ?   D . n 
D 1 294 GLU 294 294 ?   ?   ?   D . n 
D 1 295 LYS 295 295 ?   ?   ?   D . n 
D 1 296 LYS 296 296 ?   ?   ?   D . n 
D 1 297 GLY 297 297 ?   ?   ?   D . n 
D 1 298 ILE 298 298 ?   ?   ?   D . n 
D 1 299 LEU 299 299 ?   ?   ?   D . n 
D 1 300 PRO 300 300 ?   ?   ?   D . n 
D 1 301 GLU 301 301 ?   ?   ?   D . n 
D 1 302 GLY 302 302 ?   ?   ?   D . n 
D 1 303 PHE 303 303 303 PHE PHE D . n 
D 1 304 VAL 304 304 304 VAL VAL D . n 
D 1 305 GLN 305 305 305 GLN GLN D . n 
D 1 306 ARG 306 306 306 ARG ARG D . n 
D 1 307 VAL 307 307 307 VAL VAL D . n 
D 1 308 GLY 308 308 308 GLY GLY D . n 
D 1 309 ASP 309 309 309 ASP ASP D . n 
D 1 310 ARG 310 310 310 ARG ARG D . n 
D 1 311 GLY 311 311 311 GLY GLY D . n 
D 1 312 LEU 312 312 312 LEU LEU D . n 
D 1 313 VAL 313 313 313 VAL VAL D . n 
D 1 314 VAL 314 314 314 VAL VAL D . n 
D 1 315 GLU 315 315 315 GLU GLU D . n 
D 1 316 GLY 316 316 316 GLY GLY D . n 
D 1 317 TRP 317 317 317 TRP TRP D . n 
D 1 318 ALA 318 318 318 ALA ALA D . n 
D 1 319 PRO 319 319 319 PRO PRO D . n 
D 1 320 GLN 320 320 320 GLN GLN D . n 
D 1 321 ALA 321 321 321 ALA ALA D . n 
D 1 322 ARG 322 322 322 ARG ARG D . n 
D 1 323 ILE 323 323 323 ILE ILE D . n 
D 1 324 LEU 324 324 324 LEU LEU D . n 
D 1 325 GLY 325 325 325 GLY GLY D . n 
D 1 326 HIS 326 326 326 HIS HIS D . n 
D 1 327 SER 327 327 327 SER SER D . n 
D 1 328 SER 328 328 328 SER SER D . n 
D 1 329 THR 329 329 329 THR THR D . n 
D 1 330 GLY 330 330 330 GLY GLY D . n 
D 1 331 GLY 331 331 331 GLY GLY D . n 
D 1 332 PHE 332 332 332 PHE PHE D . n 
D 1 333 VAL 333 333 333 VAL VAL D . n 
D 1 334 SER 334 334 334 SER SER D . n 
D 1 335 HIS 335 335 335 HIS HIS D . n 
D 1 336 CYS 336 336 336 CYS CYS D . n 
D 1 337 GLY 337 337 337 GLY GLY D . n 
D 1 338 TRP 338 338 338 TRP TRP D . n 
D 1 339 SER 339 339 339 SER SER D . n 
D 1 340 SER 340 340 340 SER SER D . n 
D 1 341 ILE 341 341 341 ILE ILE D . n 
D 1 342 ALA 342 342 342 ALA ALA D . n 
D 1 343 GLU 343 343 343 GLU GLU D . n 
D 1 344 SER 344 344 344 SER SER D . n 
D 1 345 MET 345 345 345 MET MET D . n 
D 1 346 LYS 346 346 346 LYS LYS D . n 
D 1 347 PHE 347 347 347 PHE PHE D . n 
D 1 348 GLY 348 348 348 GLY GLY D . n 
D 1 349 VAL 349 349 349 VAL VAL D . n 
D 1 350 PRO 350 350 350 PRO PRO D . n 
D 1 351 VAL 351 351 351 VAL VAL D . n 
D 1 352 ILE 352 352 352 ILE ILE D . n 
D 1 353 ALA 353 353 353 ALA ALA D . n 
D 1 354 MET 354 354 354 MET MET D . n 
D 1 355 ALA 355 355 355 ALA ALA D . n 
D 1 356 ARG 356 356 356 ARG ARG D . n 
D 1 357 HIS 357 357 357 HIS HIS D . n 
D 1 358 LEU 358 358 358 LEU LEU D . n 
D 1 359 ASP 359 359 359 ASP ASP D . n 
D 1 360 GLN 360 360 360 GLN GLN D . n 
D 1 361 PRO 361 361 361 PRO PRO D . n 
D 1 362 LEU 362 362 362 LEU LEU D . n 
D 1 363 ASN 363 363 363 ASN ASN D . n 
D 1 364 GLY 364 364 364 GLY GLY D . n 
D 1 365 LYS 365 365 365 LYS LYS D . n 
D 1 366 LEU 366 366 366 LEU LEU D . n 
D 1 367 ALA 367 367 367 ALA ALA D . n 
D 1 368 ALA 368 368 368 ALA ALA D . n 
D 1 369 GLU 369 369 369 GLU GLU D . n 
D 1 370 VAL 370 370 370 VAL VAL D . n 
D 1 371 GLY 371 371 371 GLY GLY D . n 
D 1 372 VAL 372 372 372 VAL VAL D . n 
D 1 373 GLY 373 373 373 GLY GLY D . n 
D 1 374 MET 374 374 374 MET MET D . n 
D 1 375 GLU 375 375 375 GLU GLU D . n 
D 1 376 VAL 376 376 376 VAL VAL D . n 
D 1 377 VAL 377 377 377 VAL VAL D . n 
D 1 378 ARG 378 378 378 ARG ARG D . n 
D 1 379 ASP 379 379 379 ASP ASP D . n 
D 1 380 GLU 380 380 380 GLU GLU D . n 
D 1 381 ASN 381 381 381 ASN ASN D . n 
D 1 382 GLY 382 382 382 GLY GLY D . n 
D 1 383 LYS 383 383 383 LYS LYS D . n 
D 1 384 TYR 384 384 384 TYR TYR D . n 
D 1 385 LYS 385 385 385 LYS LYS D . n 
D 1 386 ARG 386 386 386 ARG ARG D . n 
D 1 387 GLU 387 387 387 GLU GLU D . n 
D 1 388 GLY 388 388 388 GLY GLY D . n 
D 1 389 ILE 389 389 389 ILE ILE D . n 
D 1 390 ALA 390 390 390 ALA ALA D . n 
D 1 391 GLU 391 391 391 GLU GLU D . n 
D 1 392 VAL 392 392 392 VAL VAL D . n 
D 1 393 ILE 393 393 393 ILE ILE D . n 
D 1 394 ARG 394 394 394 ARG ARG D . n 
D 1 395 LYS 395 395 395 LYS LYS D . n 
D 1 396 VAL 396 396 396 VAL VAL D . n 
D 1 397 VAL 397 397 397 VAL VAL D . n 
D 1 398 VAL 398 398 398 VAL VAL D . n 
D 1 399 GLU 399 399 399 GLU GLU D . n 
D 1 400 LYS 400 400 400 LYS LYS D . n 
D 1 401 SER 401 401 401 SER SER D . n 
D 1 402 GLY 402 402 402 GLY GLY D . n 
D 1 403 GLU 403 403 403 GLU GLU D . n 
D 1 404 VAL 404 404 404 VAL VAL D . n 
D 1 405 ILE 405 405 405 ILE ILE D . n 
D 1 406 ARG 406 406 406 ARG ARG D . n 
D 1 407 ARG 407 407 407 ARG ARG D . n 
D 1 408 LYS 408 408 408 LYS LYS D . n 
D 1 409 ALA 409 409 409 ALA ALA D . n 
D 1 410 ARG 410 410 410 ARG ARG D . n 
D 1 411 GLU 411 411 411 GLU GLU D . n 
D 1 412 LEU 412 412 412 LEU LEU D . n 
D 1 413 SER 413 413 413 SER SER D . n 
D 1 414 GLU 414 414 414 GLU GLU D . n 
D 1 415 LYS 415 415 415 LYS LYS D . n 
D 1 416 MET 416 416 416 MET MET D . n 
D 1 417 LYS 417 417 417 LYS LYS D . n 
D 1 418 GLU 418 418 418 GLU GLU D . n 
D 1 419 LYS 419 419 419 LYS LYS D . n 
D 1 420 GLY 420 420 420 GLY GLY D . n 
D 1 421 GLU 421 421 421 GLU GLU D . n 
D 1 422 GLN 422 422 422 GLN GLN D . n 
D 1 423 GLU 423 423 423 GLU GLU D . n 
D 1 424 ILE 424 424 424 ILE ILE D . n 
D 1 425 ASP 425 425 425 ASP ASP D . n 
D 1 426 ARG 426 426 426 ARG ARG D . n 
D 1 427 ALA 427 427 427 ALA ALA D . n 
D 1 428 VAL 428 428 428 VAL VAL D . n 
D 1 429 GLU 429 429 429 GLU GLU D . n 
D 1 430 GLU 430 430 430 GLU GLU D . n 
D 1 431 LEU 431 431 431 LEU LEU D . n 
D 1 432 VAL 432 432 432 VAL VAL D . n 
D 1 433 GLN 433 433 433 GLN GLN D . n 
D 1 434 ILE 434 434 434 ILE ILE D . n 
D 1 435 CYS 435 435 435 CYS CYS D . n 
D 1 436 LYS 436 436 436 LYS LYS D . n 
D 1 437 LYS 437 437 437 LYS LYS D . n 
D 1 438 LYS 438 438 438 LYS LYS D . n 
D 1 439 LYS 439 439 439 LYS LYS D . n 
D 1 440 ASP 440 440 440 ASP ASP D . n 
D 1 441 GLU 441 441 441 GLU GLU D . n 
D 1 442 GLN 442 442 442 GLN GLN D . n 
D 1 443 GLU 443 443 ?   ?   ?   D . n 
D 1 444 ASN 444 444 ?   ?   ?   D . n 
D 1 445 LEU 445 445 ?   ?   ?   D . n 
D 1 446 TYR 446 446 ?   ?   ?   D . n 
D 1 447 PHE 447 447 ?   ?   ?   D . n 
D 1 448 GLN 448 448 ?   ?   ?   D . n 
D 1 449 GLY 449 449 ?   ?   ?   D . n 
D 1 450 HIS 450 450 ?   ?   ?   D . n 
D 1 451 HIS 451 451 ?   ?   ?   D . n 
D 1 452 HIS 452 452 ?   ?   ?   D . n 
D 1 453 HIS 453 453 ?   ?   ?   D . n 
D 1 454 HIS 454 454 ?   ?   ?   D . n 
D 1 455 HIS 455 455 ?   ?   ?   D . n 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.19_4092: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                  2 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? Coot     ? ? ? .                  3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? .                  4 
# 
_cell.angle_alpha                  93.96 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  93.75 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8JZQ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     46.987 
_cell.length_a_esd                 ? 
_cell.length_b                     80.886 
_cell.length_b_esd                 ? 
_cell.length_c                     126.377 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8JZQ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8JZQ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.35 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          47.64 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              5.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.25 M ammonium acetate, 0.2 M Sodium citrate tribasic dihydrate, pH 5.0, 25% w/v PEG 4000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-05-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97852 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97852 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8JZQ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.89 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     39238 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           95.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.143 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.160 
_reflns.pdbx_Rpim_I_all                                0.091 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.992 
_reflns.pdbx_CC_star                                   0.998 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.131 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
2.90 2.95  ? ? ? ? ? ? 2010 ? ? ? ? ? ? ? ? ? ? ? 2.9 0.866 ? ? 0.899 0.495 ? 1  1 0.543 0.839 ? 95.8 ? 0.747 ? ? ? ? ? ? ? ? ? 
2.95 3.00  ? ? ? ? ? ? 1958 ? ? ? ? ? ? ? ? ? ? ? 2.8 0.893 ? ? 0.800 0.447 ? 2  1 0.496 0.814 ? 95.8 ? 0.659 ? ? ? ? ? ? ? ? ? 
3.00 3.06  ? ? ? ? ? ? 1942 ? ? ? ? ? ? ? ? ? ? ? 2.8 0.935 ? ? 0.640 0.356 ? 3  1 0.551 0.843 ? 95.2 ? 0.529 ? ? ? ? ? ? ? ? ? 
3.06 3.12  ? ? ? ? ? ? 1987 ? ? ? ? ? ? ? ? ? ? ? 2.7 1.010 ? ? 0.537 0.306 ? 4  1 0.650 0.888 ? 93.8 ? 0.438 ? ? ? ? ? ? ? ? ? 
3.12 3.19  ? ? ? ? ? ? 1863 ? ? ? ? ? ? ? ? ? ? ? 2.7 1.010 ? ? 0.529 0.300 ? 5  1 0.705 0.909 ? 93.5 ? 0.433 ? ? ? ? ? ? ? ? ? 
3.19 3.27  ? ? ? ? ? ? 2015 ? ? ? ? ? ? ? ? ? ? ? 2.9 1.082 ? ? 0.416 0.230 ? 6  1 0.791 0.940 ? 96.8 ? 0.345 ? ? ? ? ? ? ? ? ? 
3.27 3.35  ? ? ? ? ? ? 2044 ? ? ? ? ? ? ? ? ? ? ? 3.0 1.167 ? ? 0.333 0.184 ? 7  1 0.854 0.960 ? 97.0 ? 0.276 ? ? ? ? ? ? ? ? ? 
3.35 3.44  ? ? ? ? ? ? 1920 ? ? ? ? ? ? ? ? ? ? ? 2.9 1.342 ? ? 0.422 0.243 ? 8  1 0.946 0.986 ? 93.2 ? 0.342 ? ? ? ? ? ? ? ? ? 
3.44 3.54  ? ? ? ? ? ? 1895 ? ? ? ? ? ? ? ? ? ? ? 2.9 1.359 ? ? 0.375 0.216 ? 9  1 0.934 0.983 ? 92.8 ? 0.304 ? ? ? ? ? ? ? ? ? 
3.54 3.65  ? ? ? ? ? ? 2012 ? ? ? ? ? ? ? ? ? ? ? 2.9 1.105 ? ? 0.307 0.171 ? 10 1 0.955 0.988 ? 95.9 ? 0.253 ? ? ? ? ? ? ? ? ? 
3.65 3.78  ? ? ? ? ? ? 1859 ? ? ? ? ? ? ? ? ? ? ? 2.8 1.222 ? ? 0.238 0.137 ? 11 1 0.968 0.992 ? 92.5 ? 0.193 ? ? ? ? ? ? ? ? ? 
3.78 3.94  ? ? ? ? ? ? 1911 ? ? ? ? ? ? ? ? ? ? ? 2.7 1.334 ? ? 0.214 0.125 ? 12 1 0.968 0.992 ? 91.3 ? 0.171 ? ? ? ? ? ? ? ? ? 
3.94 4.11  ? ? ? ? ? ? 1924 ? ? ? ? ? ? ? ? ? ? ? 2.6 1.123 ? ? 0.141 0.081 ? 13 1 0.966 0.991 ? 94.3 ? 0.114 ? ? ? ? ? ? ? ? ? 
4.11 4.33  ? ? ? ? ? ? 2001 ? ? ? ? ? ? ? ? ? ? ? 2.8 1.250 ? ? 0.117 0.066 ? 14 1 0.978 0.994 ? 96.1 ? 0.095 ? ? ? ? ? ? ? ? ? 
4.33 4.60  ? ? ? ? ? ? 2008 ? ? ? ? ? ? ? ? ? ? ? 2.9 1.211 ? ? 0.111 0.062 ? 15 1 0.973 0.993 ? 96.9 ? 0.091 ? ? ? ? ? ? ? ? ? 
4.60 4.96  ? ? ? ? ? ? 1975 ? ? ? ? ? ? ? ? ? ? ? 2.9 1.196 ? ? 0.104 0.059 ? 16 1 0.979 0.995 ? 96.9 ? 0.086 ? ? ? ? ? ? ? ? ? 
4.96 5.46  ? ? ? ? ? ? 2000 ? ? ? ? ? ? ? ? ? ? ? 2.9 1.254 ? ? 0.105 0.059 ? 17 1 0.978 0.994 ? 96.6 ? 0.086 ? ? ? ? ? ? ? ? ? 
5.46 6.24  ? ? ? ? ? ? 1958 ? ? ? ? ? ? ? ? ? ? ? 2.7 1.217 ? ? 0.102 0.059 ? 18 1 0.991 0.998 ? 95.1 ? 0.083 ? ? ? ? ? ? ? ? ? 
6.24 7.86  ? ? ? ? ? ? 2039 ? ? ? ? ? ? ? ? ? ? ? 3.0 1.168 ? ? 0.086 0.048 ? 19 1 0.980 0.995 ? 97.2 ? 0.071 ? ? ? ? ? ? ? ? ? 
7.86 50.00 ? ? ? ? ? ? 1917 ? ? ? ? ? ? ? ? ? ? ? 2.8 1.127 ? ? 0.065 0.037 ? 20 1 0.991 0.998 ? 93.5 ? 0.052 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8JZQ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.89 
_refine.ls_d_res_low                             37.70 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     39084 
_refine.ls_number_reflns_R_free                  1922 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    94.28 
_refine.ls_percent_reflns_R_free                 4.92 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.3086 
_refine.ls_R_factor_R_free                       0.3329 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.3073 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.96 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 38.57 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.51 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.89 
_refine_hist.d_res_low                        37.70 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               11872 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        11872 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  ? 12108 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.221  ? 16344 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 13.549 ? 4484  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.072  ? 1844  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.008  ? 2088  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.89 2.96  . . 124 2583 90.00 . . . . 0.3309 . . . . . . . . . . . 0.4155 
'X-RAY DIFFRACTION' 2.96 3.04  . . 121 2640 95.00 . . . . 0.3284 . . . . . . . . . . . 0.3528 
'X-RAY DIFFRACTION' 3.04 3.13  . . 130 2697 93.00 . . . . 0.3408 . . . . . . . . . . . 0.3498 
'X-RAY DIFFRACTION' 3.13 3.23  . . 130 2657 95.00 . . . . 0.3440 . . . . . . . . . . . 0.3783 
'X-RAY DIFFRACTION' 3.23 3.35  . . 136 2776 97.00 . . . . 0.3225 . . . . . . . . . . . 0.3496 
'X-RAY DIFFRACTION' 3.35 3.48  . . 151 2479 90.00 . . . . 0.4003 . . . . . . . . . . . 0.4494 
'X-RAY DIFFRACTION' 3.48 3.64  . . 167 2729 97.00 . . . . 0.3397 . . . . . . . . . . . 0.3673 
'X-RAY DIFFRACTION' 3.64 3.83  . . 126 2584 92.00 . . . . 0.3547 . . . . . . . . . . . 0.3760 
'X-RAY DIFFRACTION' 3.83 4.07  . . 127 2568 91.00 . . . . 0.3191 . . . . . . . . . . . 0.3770 
'X-RAY DIFFRACTION' 4.07 4.39  . . 121 2706 96.00 . . . . 0.2792 . . . . . . . . . . . 0.3244 
'X-RAY DIFFRACTION' 4.39 4.83  . . 155 2716 97.00 . . . . 0.2780 . . . . . . . . . . . 0.2794 
'X-RAY DIFFRACTION' 4.83 5.53  . . 155 2683 97.00 . . . . 0.2897 . . . . . . . . . . . 0.3231 
'X-RAY DIFFRACTION' 5.53 6.95  . . 152 2687 96.00 . . . . 0.3133 . . . . . . . . . . . 0.3402 
'X-RAY DIFFRACTION' 6.95 37.70 . . 127 2657 94.00 . . . . 0.2545 . . . . . . . . . . . 0.2394 
# 
_struct.entry_id                     8JZQ 
_struct.title                        'Crystal structure of Panax quinquefolius Pq3-O-UGT2' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8JZQ 
_struct_keywords.text            'Glycosyltranferase, GT-B fold, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A0M4ME80_PANQU 
_struct_ref.pdbx_db_accession          A0A0M4ME80 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MDNQKGRISIALLPFLAHGHISPFFELAKQLAKRNCNVFLCSTPINLSSIKDKDSSASIKLVELHLPSSPDLPPHYHTTN
GLPSHLMLPLRNAFETAGPTFSEILKTLNPDLLIYDFNPSWAPEIASSHNIPAVYFLTTAAASSSIGLHAFKNPGEKYPF
PDFYDNSNIIPEPPSADNMKLLHDFIACFERSCDIILIKSFRELEGKYIDLLSTLSDKTLVPVGPLVQDPMGHNEDPKTE
QIINWLDKRAESTVVFVCFGSEYFLSNEELEEVAIGLEISTVNFIWAVRLIEGEKKGILPEGFVQRVGDRGLVVEGWAPQ
ARILGHSSTGGFVSHCGWSSIAESMKFGVPVIAMARHLDQPLNGKLAAEVGVGMEVVRDENGKYKREGIAEVIRKVVVEK
SGEVIRRKARELSEKMKEKGEQEIDRAVEELVQICKKKKDEQ
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8JZQ A 1 ? 442 ? A0A0M4ME80 1 ? 442 ? 1 442 
2 1 8JZQ B 1 ? 442 ? A0A0M4ME80 1 ? 442 ? 1 442 
3 1 8JZQ C 1 ? 442 ? A0A0M4ME80 1 ? 442 ? 1 442 
4 1 8JZQ D 1 ? 442 ? A0A0M4ME80 1 ? 442 ? 1 442 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8JZQ GLU A 443 ? UNP A0A0M4ME80 ? ? 'expression tag' 443 1  
1 8JZQ ASN A 444 ? UNP A0A0M4ME80 ? ? 'expression tag' 444 2  
1 8JZQ LEU A 445 ? UNP A0A0M4ME80 ? ? 'expression tag' 445 3  
1 8JZQ TYR A 446 ? UNP A0A0M4ME80 ? ? 'expression tag' 446 4  
1 8JZQ PHE A 447 ? UNP A0A0M4ME80 ? ? 'expression tag' 447 5  
1 8JZQ GLN A 448 ? UNP A0A0M4ME80 ? ? 'expression tag' 448 6  
1 8JZQ GLY A 449 ? UNP A0A0M4ME80 ? ? 'expression tag' 449 7  
1 8JZQ HIS A 450 ? UNP A0A0M4ME80 ? ? 'expression tag' 450 8  
1 8JZQ HIS A 451 ? UNP A0A0M4ME80 ? ? 'expression tag' 451 9  
1 8JZQ HIS A 452 ? UNP A0A0M4ME80 ? ? 'expression tag' 452 10 
1 8JZQ HIS A 453 ? UNP A0A0M4ME80 ? ? 'expression tag' 453 11 
1 8JZQ HIS A 454 ? UNP A0A0M4ME80 ? ? 'expression tag' 454 12 
1 8JZQ HIS A 455 ? UNP A0A0M4ME80 ? ? 'expression tag' 455 13 
2 8JZQ GLU B 443 ? UNP A0A0M4ME80 ? ? 'expression tag' 443 14 
2 8JZQ ASN B 444 ? UNP A0A0M4ME80 ? ? 'expression tag' 444 15 
2 8JZQ LEU B 445 ? UNP A0A0M4ME80 ? ? 'expression tag' 445 16 
2 8JZQ TYR B 446 ? UNP A0A0M4ME80 ? ? 'expression tag' 446 17 
2 8JZQ PHE B 447 ? UNP A0A0M4ME80 ? ? 'expression tag' 447 18 
2 8JZQ GLN B 448 ? UNP A0A0M4ME80 ? ? 'expression tag' 448 19 
2 8JZQ GLY B 449 ? UNP A0A0M4ME80 ? ? 'expression tag' 449 20 
2 8JZQ HIS B 450 ? UNP A0A0M4ME80 ? ? 'expression tag' 450 21 
2 8JZQ HIS B 451 ? UNP A0A0M4ME80 ? ? 'expression tag' 451 22 
2 8JZQ HIS B 452 ? UNP A0A0M4ME80 ? ? 'expression tag' 452 23 
2 8JZQ HIS B 453 ? UNP A0A0M4ME80 ? ? 'expression tag' 453 24 
2 8JZQ HIS B 454 ? UNP A0A0M4ME80 ? ? 'expression tag' 454 25 
2 8JZQ HIS B 455 ? UNP A0A0M4ME80 ? ? 'expression tag' 455 26 
3 8JZQ GLU C 443 ? UNP A0A0M4ME80 ? ? 'expression tag' 443 27 
3 8JZQ ASN C 444 ? UNP A0A0M4ME80 ? ? 'expression tag' 444 28 
3 8JZQ LEU C 445 ? UNP A0A0M4ME80 ? ? 'expression tag' 445 29 
3 8JZQ TYR C 446 ? UNP A0A0M4ME80 ? ? 'expression tag' 446 30 
3 8JZQ PHE C 447 ? UNP A0A0M4ME80 ? ? 'expression tag' 447 31 
3 8JZQ GLN C 448 ? UNP A0A0M4ME80 ? ? 'expression tag' 448 32 
3 8JZQ GLY C 449 ? UNP A0A0M4ME80 ? ? 'expression tag' 449 33 
3 8JZQ HIS C 450 ? UNP A0A0M4ME80 ? ? 'expression tag' 450 34 
3 8JZQ HIS C 451 ? UNP A0A0M4ME80 ? ? 'expression tag' 451 35 
3 8JZQ HIS C 452 ? UNP A0A0M4ME80 ? ? 'expression tag' 452 36 
3 8JZQ HIS C 453 ? UNP A0A0M4ME80 ? ? 'expression tag' 453 37 
3 8JZQ HIS C 454 ? UNP A0A0M4ME80 ? ? 'expression tag' 454 38 
3 8JZQ HIS C 455 ? UNP A0A0M4ME80 ? ? 'expression tag' 455 39 
4 8JZQ GLU D 443 ? UNP A0A0M4ME80 ? ? 'expression tag' 443 40 
4 8JZQ ASN D 444 ? UNP A0A0M4ME80 ? ? 'expression tag' 444 41 
4 8JZQ LEU D 445 ? UNP A0A0M4ME80 ? ? 'expression tag' 445 42 
4 8JZQ TYR D 446 ? UNP A0A0M4ME80 ? ? 'expression tag' 446 43 
4 8JZQ PHE D 447 ? UNP A0A0M4ME80 ? ? 'expression tag' 447 44 
4 8JZQ GLN D 448 ? UNP A0A0M4ME80 ? ? 'expression tag' 448 45 
4 8JZQ GLY D 449 ? UNP A0A0M4ME80 ? ? 'expression tag' 449 46 
4 8JZQ HIS D 450 ? UNP A0A0M4ME80 ? ? 'expression tag' 450 47 
4 8JZQ HIS D 451 ? UNP A0A0M4ME80 ? ? 'expression tag' 451 48 
4 8JZQ HIS D 452 ? UNP A0A0M4ME80 ? ? 'expression tag' 452 49 
4 8JZQ HIS D 453 ? UNP A0A0M4ME80 ? ? 'expression tag' 453 50 
4 8JZQ HIS D 454 ? UNP A0A0M4ME80 ? ? 'expression tag' 454 51 
4 8JZQ HIS D 455 ? UNP A0A0M4ME80 ? ? 'expression tag' 455 52 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
4 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A 
2 1 B 
3 1 C 
4 1 D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 17  ? LYS A 33  ? ALA A 17  LYS A 33  1 ? 17 
HELX_P HELX_P2  AA2 PRO A 44  ? LYS A 51  ? PRO A 44  LYS A 51  1 ? 8  
HELX_P HELX_P3  AA3 ASN A 92  ? THR A 96  ? ASN A 92  THR A 96  5 ? 5  
HELX_P HELX_P4  AA4 ALA A 97  ? ASN A 109 ? ALA A 97  ASN A 109 1 ? 13 
HELX_P HELX_P5  AA5 SER A 120 ? SER A 128 ? SER A 120 SER A 128 1 ? 9  
HELX_P HELX_P6  AA6 ALA A 140 ? ASN A 153 ? ALA A 140 ASN A 153 1 ? 14 
HELX_P HELX_P7  AA7 LEU A 181 ? ARG A 191 ? LEU A 181 ARG A 191 1 ? 11 
HELX_P HELX_P8  AA8 PHE A 201 ? ASP A 217 ? PHE A 201 ASP A 217 1 ? 17 
HELX_P HELX_P9  AA9 THR A 239 ? LYS A 248 ? THR A 239 LYS A 248 1 ? 10 
HELX_P HELX_P10 AB1 GLU A 268 ? ILE A 279 ? GLU A 268 ILE A 279 1 ? 12 
HELX_P HELX_P11 AB2 PRO A 319 ? HIS A 326 ? PRO A 319 HIS A 326 1 ? 8  
HELX_P HELX_P12 AB3 GLY A 337 ? PHE A 347 ? GLY A 337 PHE A 347 1 ? 11 
HELX_P HELX_P13 AB4 ASP A 359 ? GLY A 371 ? ASP A 359 GLY A 371 1 ? 13 
HELX_P HELX_P14 AB5 LYS A 385 ? VAL A 398 ? LYS A 385 VAL A 398 1 ? 14 
HELX_P HELX_P15 AB6 GLU A 399 ? SER A 401 ? GLU A 399 SER A 401 5 ? 3  
HELX_P HELX_P16 AB7 GLY A 402 ? LYS A 419 ? GLY A 402 LYS A 419 1 ? 18 
HELX_P HELX_P17 AB8 GLU A 421 ? LYS A 438 ? GLU A 421 LYS A 438 1 ? 18 
HELX_P HELX_P18 AB9 ALA B 17  ? LYS B 33  ? ALA B 17  LYS B 33  1 ? 17 
HELX_P HELX_P19 AC1 PRO B 44  ? LYS B 51  ? PRO B 44  LYS B 51  1 ? 8  
HELX_P HELX_P20 AC2 ASN B 92  ? THR B 96  ? ASN B 92  THR B 96  5 ? 5  
HELX_P HELX_P21 AC3 ALA B 97  ? ASN B 109 ? ALA B 97  ASN B 109 1 ? 13 
HELX_P HELX_P22 AC4 SER B 120 ? SER B 128 ? SER B 120 SER B 128 1 ? 9  
HELX_P HELX_P23 AC5 ALA B 140 ? ASN B 153 ? ALA B 140 ASN B 153 1 ? 14 
HELX_P HELX_P24 AC6 LEU B 181 ? ARG B 191 ? LEU B 181 ARG B 191 1 ? 11 
HELX_P HELX_P25 AC7 PHE B 201 ? ASP B 217 ? PHE B 201 ASP B 217 1 ? 17 
HELX_P HELX_P26 AC8 THR B 239 ? LYS B 248 ? THR B 239 LYS B 248 1 ? 10 
HELX_P HELX_P27 AC9 GLU B 268 ? ILE B 279 ? GLU B 268 ILE B 279 1 ? 12 
HELX_P HELX_P28 AD1 PRO B 319 ? HIS B 326 ? PRO B 319 HIS B 326 1 ? 8  
HELX_P HELX_P29 AD2 GLY B 337 ? PHE B 347 ? GLY B 337 PHE B 347 1 ? 11 
HELX_P HELX_P30 AD3 ASP B 359 ? GLY B 371 ? ASP B 359 GLY B 371 1 ? 13 
HELX_P HELX_P31 AD4 LYS B 385 ? VAL B 398 ? LYS B 385 VAL B 398 1 ? 14 
HELX_P HELX_P32 AD5 GLU B 399 ? SER B 401 ? GLU B 399 SER B 401 5 ? 3  
HELX_P HELX_P33 AD6 GLY B 402 ? LYS B 419 ? GLY B 402 LYS B 419 1 ? 18 
HELX_P HELX_P34 AD7 GLU B 421 ? LYS B 438 ? GLU B 421 LYS B 438 1 ? 18 
HELX_P HELX_P35 AD8 ALA C 17  ? LYS C 33  ? ALA C 17  LYS C 33  1 ? 17 
HELX_P HELX_P36 AD9 PRO C 44  ? LYS C 51  ? PRO C 44  LYS C 51  1 ? 8  
HELX_P HELX_P37 AE1 ASN C 92  ? THR C 96  ? ASN C 92  THR C 96  5 ? 5  
HELX_P HELX_P38 AE2 ALA C 97  ? ASN C 109 ? ALA C 97  ASN C 109 1 ? 13 
HELX_P HELX_P39 AE3 SER C 120 ? SER C 128 ? SER C 120 SER C 128 1 ? 9  
HELX_P HELX_P40 AE4 ALA C 140 ? ASN C 153 ? ALA C 140 ASN C 153 1 ? 14 
HELX_P HELX_P41 AE5 LEU C 181 ? ARG C 191 ? LEU C 181 ARG C 191 1 ? 11 
HELX_P HELX_P42 AE6 PHE C 201 ? ASP C 217 ? PHE C 201 ASP C 217 1 ? 17 
HELX_P HELX_P43 AE7 THR C 239 ? LYS C 248 ? THR C 239 LYS C 248 1 ? 10 
HELX_P HELX_P44 AE8 GLU C 268 ? ILE C 279 ? GLU C 268 ILE C 279 1 ? 12 
HELX_P HELX_P45 AE9 PRO C 319 ? HIS C 326 ? PRO C 319 HIS C 326 1 ? 8  
HELX_P HELX_P46 AF1 GLY C 337 ? PHE C 347 ? GLY C 337 PHE C 347 1 ? 11 
HELX_P HELX_P47 AF2 ASP C 359 ? GLY C 371 ? ASP C 359 GLY C 371 1 ? 13 
HELX_P HELX_P48 AF3 LYS C 385 ? VAL C 398 ? LYS C 385 VAL C 398 1 ? 14 
HELX_P HELX_P49 AF4 GLU C 399 ? SER C 401 ? GLU C 399 SER C 401 5 ? 3  
HELX_P HELX_P50 AF5 GLY C 402 ? LYS C 419 ? GLY C 402 LYS C 419 1 ? 18 
HELX_P HELX_P51 AF6 GLU C 421 ? LYS C 438 ? GLU C 421 LYS C 438 1 ? 18 
HELX_P HELX_P52 AF7 ALA D 17  ? LYS D 33  ? ALA D 17  LYS D 33  1 ? 17 
HELX_P HELX_P53 AF8 PRO D 44  ? LYS D 51  ? PRO D 44  LYS D 51  1 ? 8  
HELX_P HELX_P54 AF9 ASN D 92  ? THR D 96  ? ASN D 92  THR D 96  5 ? 5  
HELX_P HELX_P55 AG1 ALA D 97  ? ASN D 109 ? ALA D 97  ASN D 109 1 ? 13 
HELX_P HELX_P56 AG2 SER D 120 ? SER D 128 ? SER D 120 SER D 128 1 ? 9  
HELX_P HELX_P57 AG3 ALA D 140 ? ASN D 153 ? ALA D 140 ASN D 153 1 ? 14 
HELX_P HELX_P58 AG4 LEU D 181 ? ARG D 191 ? LEU D 181 ARG D 191 1 ? 11 
HELX_P HELX_P59 AG5 PHE D 201 ? ASP D 217 ? PHE D 201 ASP D 217 1 ? 17 
HELX_P HELX_P60 AG6 THR D 239 ? LYS D 248 ? THR D 239 LYS D 248 1 ? 10 
HELX_P HELX_P61 AG7 GLU D 268 ? ILE D 279 ? GLU D 268 ILE D 279 1 ? 12 
HELX_P HELX_P62 AG8 PRO D 319 ? HIS D 326 ? PRO D 319 HIS D 326 1 ? 8  
HELX_P HELX_P63 AG9 GLY D 337 ? PHE D 347 ? GLY D 337 PHE D 347 1 ? 11 
HELX_P HELX_P64 AH1 ASP D 359 ? GLY D 371 ? ASP D 359 GLY D 371 1 ? 13 
HELX_P HELX_P65 AH2 LYS D 385 ? VAL D 398 ? LYS D 385 VAL D 398 1 ? 14 
HELX_P HELX_P66 AH3 GLU D 399 ? SER D 401 ? GLU D 399 SER D 401 5 ? 3  
HELX_P HELX_P67 AH4 GLY D 402 ? LYS D 419 ? GLY D 402 LYS D 419 1 ? 18 
HELX_P HELX_P68 AH5 GLU D 421 ? LYS D 438 ? GLU D 421 LYS D 438 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 6 ? 
AA3 ? 7 ? 
AA4 ? 6 ? 
AA5 ? 7 ? 
AA6 ? 6 ? 
AA7 ? 7 ? 
AA8 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA1 4 5 ? parallel 
AA1 5 6 ? parallel 
AA1 6 7 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
AA2 4 5 ? parallel 
AA2 5 6 ? parallel 
AA3 1 2 ? parallel 
AA3 2 3 ? parallel 
AA3 3 4 ? parallel 
AA3 4 5 ? parallel 
AA3 5 6 ? parallel 
AA3 6 7 ? parallel 
AA4 1 2 ? parallel 
AA4 2 3 ? parallel 
AA4 3 4 ? parallel 
AA4 4 5 ? parallel 
AA4 5 6 ? parallel 
AA5 1 2 ? parallel 
AA5 2 3 ? parallel 
AA5 3 4 ? parallel 
AA5 4 5 ? parallel 
AA5 5 6 ? parallel 
AA5 6 7 ? parallel 
AA6 1 2 ? parallel 
AA6 2 3 ? parallel 
AA6 3 4 ? parallel 
AA6 4 5 ? parallel 
AA6 5 6 ? parallel 
AA7 1 2 ? parallel 
AA7 2 3 ? parallel 
AA7 3 4 ? parallel 
AA7 4 5 ? parallel 
AA7 5 6 ? parallel 
AA7 6 7 ? parallel 
AA8 1 2 ? parallel 
AA8 2 3 ? parallel 
AA8 3 4 ? parallel 
AA8 4 5 ? parallel 
AA8 5 6 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 59  ? VAL A 62  ? ILE A 59  VAL A 62  
AA1 2 VAL A 38  ? THR A 43  ? VAL A 38  THR A 43  
AA1 3 SER A 9   ? LEU A 13  ? SER A 9   LEU A 13  
AA1 4 LEU A 113 ? TYR A 115 ? LEU A 113 TYR A 115 
AA1 5 ALA A 133 ? LEU A 137 ? ALA A 133 LEU A 137 
AA1 6 ILE A 195 ? ILE A 198 ? ILE A 195 ILE A 198 
AA1 7 THR A 219 ? PRO A 222 ? THR A 219 PRO A 222 
AA2 1 GLY A 311 ? VAL A 314 ? GLY A 311 VAL A 314 
AA2 2 ASN A 283 ? ALA A 287 ? ASN A 283 ALA A 287 
AA2 3 VAL A 254 ? CYS A 258 ? VAL A 254 CYS A 258 
AA2 4 THR A 329 ? SER A 334 ? THR A 329 SER A 334 
AA2 5 VAL A 351 ? ALA A 353 ? VAL A 351 ALA A 353 
AA2 6 GLY A 373 ? GLU A 375 ? GLY A 373 GLU A 375 
AA3 1 ILE B 59  ? LEU B 61  ? ILE B 59  LEU B 61  
AA3 2 VAL B 38  ? SER B 42  ? VAL B 38  SER B 42  
AA3 3 SER B 9   ? LEU B 13  ? SER B 9   LEU B 13  
AA3 4 LEU B 113 ? TYR B 115 ? LEU B 113 TYR B 115 
AA3 5 ALA B 133 ? LEU B 137 ? ALA B 133 LEU B 137 
AA3 6 ILE B 195 ? ILE B 198 ? ILE B 195 ILE B 198 
AA3 7 THR B 219 ? PRO B 222 ? THR B 219 PRO B 222 
AA4 1 GLY B 311 ? VAL B 314 ? GLY B 311 VAL B 314 
AA4 2 ASN B 283 ? ALA B 287 ? ASN B 283 ALA B 287 
AA4 3 VAL B 254 ? CYS B 258 ? VAL B 254 CYS B 258 
AA4 4 THR B 329 ? SER B 334 ? THR B 329 SER B 334 
AA4 5 VAL B 351 ? ALA B 353 ? VAL B 351 ALA B 353 
AA4 6 GLY B 373 ? GLU B 375 ? GLY B 373 GLU B 375 
AA5 1 ILE C 59  ? LEU C 61  ? ILE C 59  LEU C 61  
AA5 2 VAL C 38  ? SER C 42  ? VAL C 38  SER C 42  
AA5 3 SER C 9   ? LEU C 13  ? SER C 9   LEU C 13  
AA5 4 LEU C 113 ? TYR C 115 ? LEU C 113 TYR C 115 
AA5 5 ALA C 133 ? LEU C 137 ? ALA C 133 LEU C 137 
AA5 6 ILE C 195 ? ILE C 198 ? ILE C 195 ILE C 198 
AA5 7 THR C 219 ? PRO C 222 ? THR C 219 PRO C 222 
AA6 1 GLY C 311 ? VAL C 314 ? GLY C 311 VAL C 314 
AA6 2 ASN C 283 ? ALA C 287 ? ASN C 283 ALA C 287 
AA6 3 VAL C 254 ? CYS C 258 ? VAL C 254 CYS C 258 
AA6 4 THR C 329 ? SER C 334 ? THR C 329 SER C 334 
AA6 5 VAL C 351 ? ALA C 353 ? VAL C 351 ALA C 353 
AA6 6 GLY C 373 ? GLU C 375 ? GLY C 373 GLU C 375 
AA7 1 ILE D 59  ? LEU D 61  ? ILE D 59  LEU D 61  
AA7 2 PHE D 39  ? SER D 42  ? PHE D 39  SER D 42  
AA7 3 ILE D 10  ? LEU D 13  ? ILE D 10  LEU D 13  
AA7 4 LEU D 113 ? TYR D 115 ? LEU D 113 TYR D 115 
AA7 5 ALA D 133 ? LEU D 137 ? ALA D 133 LEU D 137 
AA7 6 ILE D 195 ? ILE D 198 ? ILE D 195 ILE D 198 
AA7 7 THR D 219 ? PRO D 222 ? THR D 219 PRO D 222 
AA8 1 GLY D 311 ? VAL D 314 ? GLY D 311 VAL D 314 
AA8 2 ASN D 283 ? ALA D 287 ? ASN D 283 ALA D 287 
AA8 3 VAL D 254 ? CYS D 258 ? VAL D 254 CYS D 258 
AA8 4 THR D 329 ? SER D 334 ? THR D 329 SER D 334 
AA8 5 VAL D 351 ? ALA D 353 ? VAL D 351 ALA D 353 
AA8 6 GLY D 373 ? GLU D 375 ? GLY D 373 GLU D 375 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 61  ? O LEU A 61  N CYS A 41  ? N CYS A 41  
AA1 2 3 O SER A 42  ? O SER A 42  N LEU A 12  ? N LEU A 12  
AA1 3 4 N ALA A 11  ? N ALA A 11  O ILE A 114 ? O ILE A 114 
AA1 4 5 N LEU A 113 ? N LEU A 113 O VAL A 134 ? O VAL A 134 
AA1 5 6 N LEU A 137 ? N LEU A 137 O LEU A 197 ? O LEU A 197 
AA1 6 7 N ILE A 196 ? N ILE A 196 O VAL A 221 ? O VAL A 221 
AA2 1 2 O VAL A 314 ? O VAL A 314 N TRP A 286 ? N TRP A 286 
AA2 2 3 O ILE A 285 ? O ILE A 285 N VAL A 257 ? N VAL A 257 
AA2 3 4 N PHE A 256 ? N PHE A 256 O GLY A 331 ? O GLY A 331 
AA2 4 5 N PHE A 332 ? N PHE A 332 O ILE A 352 ? O ILE A 352 
AA2 5 6 N ALA A 353 ? N ALA A 353 O MET A 374 ? O MET A 374 
AA3 1 2 O LEU B 61  ? O LEU B 61  N CYS B 41  ? N CYS B 41  
AA3 2 3 O SER B 42  ? O SER B 42  N LEU B 12  ? N LEU B 12  
AA3 3 4 N ALA B 11  ? N ALA B 11  O ILE B 114 ? O ILE B 114 
AA3 4 5 N LEU B 113 ? N LEU B 113 O VAL B 134 ? O VAL B 134 
AA3 5 6 N LEU B 137 ? N LEU B 137 O LEU B 197 ? O LEU B 197 
AA3 6 7 N ILE B 196 ? N ILE B 196 O VAL B 221 ? O VAL B 221 
AA4 1 2 O VAL B 314 ? O VAL B 314 N TRP B 286 ? N TRP B 286 
AA4 2 3 O ILE B 285 ? O ILE B 285 N VAL B 257 ? N VAL B 257 
AA4 3 4 N PHE B 256 ? N PHE B 256 O GLY B 331 ? O GLY B 331 
AA4 4 5 N PHE B 332 ? N PHE B 332 O ILE B 352 ? O ILE B 352 
AA4 5 6 N ALA B 353 ? N ALA B 353 O MET B 374 ? O MET B 374 
AA5 1 2 O LEU C 61  ? O LEU C 61  N CYS C 41  ? N CYS C 41  
AA5 2 3 O SER C 42  ? O SER C 42  N LEU C 12  ? N LEU C 12  
AA5 3 4 N ALA C 11  ? N ALA C 11  O ILE C 114 ? O ILE C 114 
AA5 4 5 N LEU C 113 ? N LEU C 113 O VAL C 134 ? O VAL C 134 
AA5 5 6 N LEU C 137 ? N LEU C 137 O LEU C 197 ? O LEU C 197 
AA5 6 7 N ILE C 196 ? N ILE C 196 O VAL C 221 ? O VAL C 221 
AA6 1 2 O VAL C 314 ? O VAL C 314 N TRP C 286 ? N TRP C 286 
AA6 2 3 O ILE C 285 ? O ILE C 285 N VAL C 257 ? N VAL C 257 
AA6 3 4 N PHE C 256 ? N PHE C 256 O GLY C 331 ? O GLY C 331 
AA6 4 5 N PHE C 332 ? N PHE C 332 O ILE C 352 ? O ILE C 352 
AA6 5 6 N ALA C 353 ? N ALA C 353 O MET C 374 ? O MET C 374 
AA7 1 2 O LEU D 61  ? O LEU D 61  N CYS D 41  ? N CYS D 41  
AA7 2 3 O SER D 42  ? O SER D 42  N LEU D 12  ? N LEU D 12  
AA7 3 4 N ALA D 11  ? N ALA D 11  O ILE D 114 ? O ILE D 114 
AA7 4 5 N LEU D 113 ? N LEU D 113 O VAL D 134 ? O VAL D 134 
AA7 5 6 N LEU D 137 ? N LEU D 137 O LEU D 197 ? O LEU D 197 
AA7 6 7 N ILE D 196 ? N ILE D 196 O VAL D 221 ? O VAL D 221 
AA8 1 2 O VAL D 314 ? O VAL D 314 N TRP D 286 ? N TRP D 286 
AA8 2 3 O ILE D 285 ? O ILE D 285 N VAL D 257 ? N VAL D 257 
AA8 3 4 N PHE D 256 ? N PHE D 256 O GLY D 331 ? O GLY D 331 
AA8 4 5 N PHE D 332 ? N PHE D 332 O ILE D 352 ? O ILE D 352 
AA8 5 6 N ALA D 353 ? N ALA D 353 O MET D 374 ? O MET D 374 
# 
_pdbx_entry_details.entry_id                   8JZQ 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 CG2 C VAL 304 ? ? NH1 D ARG 306 ? ? 1.15 
2  1 OE1 B GLU 262 ? ? NE2 B GLN 360 ? ? 1.81 
3  1 OE1 C GLU 262 ? ? NE2 C GLN 360 ? ? 1.81 
4  1 OE1 A GLU 262 ? ? NE2 A GLN 360 ? ? 1.81 
5  1 OE1 D GLU 262 ? ? NE2 D GLN 360 ? ? 1.81 
6  1 CG2 C VAL 304 ? ? CZ  D ARG 306 ? ? 1.81 
7  1 CD1 B LEU 265 ? ? CB  B GLU 269 ? ? 1.87 
8  1 CD1 A LEU 265 ? ? CB  A GLU 269 ? ? 1.87 
9  1 CD1 C LEU 265 ? ? CB  C GLU 269 ? ? 1.87 
10 1 CD1 D LEU 265 ? ? CB  D GLU 269 ? ? 1.87 
11 1 O   C ASN 37  ? ? CE2 C PHE 39  ? ? 2.13 
12 1 O   D ASN 37  ? ? CE2 D PHE 39  ? ? 2.13 
13 1 O   A ASN 37  ? ? CE2 A PHE 39  ? ? 2.13 
14 1 O   B ASN 37  ? ? CE2 B PHE 39  ? ? 2.13 
15 1 CG2 C VAL 304 ? ? NH2 D ARG 306 ? ? 2.13 
16 1 O   C ASN 37  ? ? CD2 C PHE 39  ? ? 2.14 
17 1 O   A ASN 37  ? ? CD2 A PHE 39  ? ? 2.14 
18 1 O   D ASN 37  ? ? CD2 D PHE 39  ? ? 2.14 
19 1 O   B ASN 37  ? ? CD2 B PHE 39  ? ? 2.14 
20 1 NZ  C LYS 157 ? ? N   C ASN 166 ? ? 2.17 
21 1 NZ  B LYS 157 ? ? N   B ASN 166 ? ? 2.17 
22 1 NZ  D LYS 157 ? ? N   D ASN 166 ? ? 2.17 
23 1 NZ  A LYS 157 ? ? N   A ASN 166 ? ? 2.17 
24 1 NZ  C LYS 157 ? ? OD1 C ASP 165 ? ? 2.19 
25 1 NZ  A LYS 157 ? ? OD1 A ASP 165 ? ? 2.19 
26 1 NZ  B LYS 157 ? ? OD1 B ASP 165 ? ? 2.19 
27 1 NZ  D LYS 157 ? ? OD1 D ASP 165 ? ? 2.19 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1  1 CD1 D LEU 64  ? ? 1_555 OE1 D GLU 156 ? ? 1_455 1.09 
2  1 CD1 B LEU 64  ? ? 1_555 OE1 B GLU 156 ? ? 1_455 1.10 
3  1 CD2 A LEU 64  ? ? 1_555 OE1 A GLU 156 ? ? 1_655 1.17 
4  1 CB  A LEU 64  ? ? 1_555 OE2 A GLU 156 ? ? 1_655 1.36 
5  1 OE2 B GLU 414 ? ? 1_555 NZ  D LYS 33  ? ? 1_565 1.39 
6  1 CD1 C LEU 64  ? ? 1_555 OE1 C GLU 156 ? ? 1_655 1.39 
7  1 CA  B LEU 64  ? ? 1_555 OE2 B GLU 156 ? ? 1_455 1.46 
8  1 CA  D LEU 64  ? ? 1_555 OE2 D GLU 156 ? ? 1_455 1.47 
9  1 CA  A LEU 64  ? ? 1_555 OE2 A GLU 156 ? ? 1_655 1.57 
10 1 NH2 A ARG 306 ? ? 1_555 CB  B GLN 305 ? ? 1_654 1.69 
11 1 CA  C LEU 64  ? ? 1_555 OE2 C GLU 156 ? ? 1_655 1.69 
12 1 OE2 B GLU 414 ? ? 1_555 CE  D LYS 33  ? ? 1_565 1.70 
13 1 C   C LEU 64  ? ? 1_555 OE2 C GLU 156 ? ? 1_655 1.72 
14 1 CB  B LEU 64  ? ? 1_555 OE2 B GLU 156 ? ? 1_455 1.75 
15 1 CB  D LEU 64  ? ? 1_555 OE2 D GLU 156 ? ? 1_455 1.77 
16 1 N   C HIS 65  ? ? 1_555 OE2 C GLU 156 ? ? 1_655 1.78 
17 1 C   B LEU 64  ? ? 1_555 OE2 B GLU 156 ? ? 1_455 1.85 
18 1 CB  C LEU 64  ? ? 1_555 OE2 C GLU 156 ? ? 1_655 1.86 
19 1 C   D LEU 64  ? ? 1_555 OE2 D GLU 156 ? ? 1_455 1.88 
20 1 N   B HIS 65  ? ? 1_555 OE2 B GLU 156 ? ? 1_455 1.97 
21 1 N   D HIS 65  ? ? 1_555 OE2 D GLU 156 ? ? 1_455 1.99 
22 1 CG  A LEU 64  ? ? 1_555 OE1 A GLU 156 ? ? 1_655 2.02 
23 1 CB  A LEU 64  ? ? 1_555 CD  A GLU 156 ? ? 1_655 2.03 
24 1 C   A LEU 64  ? ? 1_555 OE2 A GLU 156 ? ? 1_655 2.08 
25 1 CG  C LEU 64  ? ? 1_555 OE1 C GLU 156 ? ? 1_655 2.13 
26 1 CG  B LEU 64  ? ? 1_555 OE1 B GLU 156 ? ? 1_455 2.17 
27 1 CD  B GLU 414 ? ? 1_555 NZ  D LYS 33  ? ? 1_565 2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 53  ? ? -159.74 -64.91  
2  1 LEU A 112 ? ? -171.77 148.96  
3  1 ASP A 116 ? ? -102.40 -153.62 
4  1 SER A 120 ? ? 60.18   -60.15  
5  1 LYS A 157 ? ? 79.00   143.33  
6  1 MET A 179 ? ? -152.28 -36.34  
7  1 ASP A 194 ? ? 65.29   -59.96  
8  1 GLU A 205 ? ? -155.20 48.92   
9  1 LEU A 265 ? ? 62.53   -140.47 
10 1 VAL A 304 ? ? 41.40   28.14   
11 1 GLN A 305 ? ? 62.75   -14.10  
12 1 ASP A 309 ? ? -66.29  77.64   
13 1 ARG A 310 ? ? 59.05   73.91   
14 1 GLU A 315 ? ? -75.19  -70.80  
15 1 ARG A 356 ? ? -149.74 -51.66  
16 1 LEU A 358 ? ? 60.85   -151.88 
17 1 GLU A 380 ? ? -109.25 -134.83 
18 1 LYS A 419 ? ? -97.60  42.73   
19 1 GLU A 421 ? ? 80.39   -23.49  
20 1 LYS B 53  ? ? -159.69 -64.92  
21 1 GLU B 63  ? ? -164.70 118.32  
22 1 LEU B 112 ? ? -171.80 148.96  
23 1 ASP B 116 ? ? -102.47 -153.66 
24 1 SER B 120 ? ? 60.19   -60.20  
25 1 LYS B 157 ? ? 78.98   143.33  
26 1 MET B 179 ? ? -152.28 -36.32  
27 1 ASP B 194 ? ? 65.25   -59.94  
28 1 GLU B 205 ? ? -155.18 48.90   
29 1 LEU B 265 ? ? 62.53   -140.46 
30 1 VAL B 304 ? ? 41.40   28.13   
31 1 GLN B 305 ? ? 62.79   -13.88  
32 1 ASP B 309 ? ? -66.30  77.63   
33 1 ARG B 310 ? ? 59.08   73.85   
34 1 GLU B 315 ? ? -75.24  -70.79  
35 1 ARG B 356 ? ? -149.74 -51.68  
36 1 LEU B 358 ? ? 60.84   -151.88 
37 1 GLU B 380 ? ? -109.27 -134.87 
38 1 LYS B 419 ? ? -97.57  42.73   
39 1 GLU B 421 ? ? 80.39   -23.47  
40 1 LYS C 53  ? ? -159.71 -64.92  
41 1 GLU C 63  ? ? -164.67 118.37  
42 1 LEU C 112 ? ? -171.71 149.00  
43 1 ASP C 116 ? ? -102.44 -153.63 
44 1 SER C 120 ? ? 60.14   -60.10  
45 1 LYS C 157 ? ? 79.05   143.33  
46 1 MET C 179 ? ? -152.32 -36.34  
47 1 ASP C 194 ? ? 65.25   -59.97  
48 1 GLU C 205 ? ? -155.14 48.87   
49 1 LEU C 265 ? ? 62.51   -140.42 
50 1 VAL C 304 ? ? 41.48   28.10   
51 1 GLN C 305 ? ? 62.70   -13.80  
52 1 ASP C 309 ? ? -66.33  77.64   
53 1 ARG C 310 ? ? 59.06   73.84   
54 1 GLU C 315 ? ? -75.22  -70.80  
55 1 ARG C 356 ? ? -149.80 -51.65  
56 1 LEU C 358 ? ? 60.79   -151.83 
57 1 GLU C 380 ? ? -109.24 -134.83 
58 1 LYS C 419 ? ? -97.55  42.71   
59 1 GLU C 421 ? ? 80.38   -23.50  
60 1 LYS D 53  ? ? -159.74 -64.91  
61 1 GLU D 63  ? ? -164.67 118.34  
62 1 LEU D 112 ? ? -171.74 148.92  
63 1 ASP D 116 ? ? -102.47 -153.64 
64 1 SER D 120 ? ? 60.12   -60.14  
65 1 LYS D 157 ? ? 78.98   143.39  
66 1 MET D 179 ? ? -152.25 -36.28  
67 1 ASP D 194 ? ? 65.36   -59.98  
68 1 GLU D 205 ? ? -155.19 48.88   
69 1 LEU D 265 ? ? 62.51   -140.45 
70 1 VAL D 304 ? ? 41.35   28.17   
71 1 GLN D 305 ? ? 62.75   -13.82  
72 1 ASP D 309 ? ? -66.24  77.60   
73 1 ARG D 310 ? ? 59.02   73.93   
74 1 GLU D 315 ? ? -75.26  -70.78  
75 1 ARG D 356 ? ? -149.76 -51.69  
76 1 LEU D 358 ? ? 60.87   -151.91 
77 1 GLU D 380 ? ? -109.21 -134.82 
78 1 LYS D 419 ? ? -97.59  42.70   
79 1 GLU D 421 ? ? 80.41   -23.52  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ASP 2   ? A ASP 2   
3   1 Y 1 A ASN 3   ? A ASN 3   
4   1 Y 1 A GLN 4   ? A GLN 4   
5   1 Y 1 A LYS 5   ? A LYS 5   
6   1 Y 1 A GLY 6   ? A GLY 6   
7   1 Y 1 A ARG 7   ? A ARG 7   
8   1 Y 1 A LEU 66  ? A LEU 66  
9   1 Y 1 A PRO 67  ? A PRO 67  
10  1 Y 1 A SER 68  ? A SER 68  
11  1 Y 1 A SER 69  ? A SER 69  
12  1 Y 1 A PRO 70  ? A PRO 70  
13  1 Y 1 A ASP 71  ? A ASP 71  
14  1 Y 1 A LEU 72  ? A LEU 72  
15  1 Y 1 A PRO 73  ? A PRO 73  
16  1 Y 1 A PRO 74  ? A PRO 74  
17  1 Y 1 A HIS 75  ? A HIS 75  
18  1 Y 1 A TYR 76  ? A TYR 76  
19  1 Y 1 A HIS 77  ? A HIS 77  
20  1 Y 1 A THR 78  ? A THR 78  
21  1 Y 1 A THR 79  ? A THR 79  
22  1 Y 1 A ASN 80  ? A ASN 80  
23  1 Y 1 A GLY 81  ? A GLY 81  
24  1 Y 1 A LEU 82  ? A LEU 82  
25  1 Y 1 A PRO 83  ? A PRO 83  
26  1 Y 1 A SER 84  ? A SER 84  
27  1 Y 1 A HIS 85  ? A HIS 85  
28  1 Y 1 A LEU 86  ? A LEU 86  
29  1 Y 1 A MET 87  ? A MET 87  
30  1 Y 1 A LEU 88  ? A LEU 88  
31  1 Y 1 A PRO 89  ? A PRO 89  
32  1 Y 1 A LEU 90  ? A LEU 90  
33  1 Y 1 A ASN 168 ? A ASN 168 
34  1 Y 1 A ILE 169 ? A ILE 169 
35  1 Y 1 A ILE 170 ? A ILE 170 
36  1 Y 1 A PRO 171 ? A PRO 171 
37  1 Y 1 A GLU 172 ? A GLU 172 
38  1 Y 1 A PRO 173 ? A PRO 173 
39  1 Y 1 A PRO 174 ? A PRO 174 
40  1 Y 1 A SER 175 ? A SER 175 
41  1 Y 1 A ALA 176 ? A ALA 176 
42  1 Y 1 A ASP 177 ? A ASP 177 
43  1 Y 1 A GLN 228 ? A GLN 228 
44  1 Y 1 A ASP 229 ? A ASP 229 
45  1 Y 1 A PRO 230 ? A PRO 230 
46  1 Y 1 A MET 231 ? A MET 231 
47  1 Y 1 A GLY 232 ? A GLY 232 
48  1 Y 1 A HIS 233 ? A HIS 233 
49  1 Y 1 A ASN 234 ? A ASN 234 
50  1 Y 1 A GLU 235 ? A GLU 235 
51  1 Y 1 A ARG 289 ? A ARG 289 
52  1 Y 1 A LEU 290 ? A LEU 290 
53  1 Y 1 A ILE 291 ? A ILE 291 
54  1 Y 1 A GLU 292 ? A GLU 292 
55  1 Y 1 A GLY 293 ? A GLY 293 
56  1 Y 1 A GLU 294 ? A GLU 294 
57  1 Y 1 A LYS 295 ? A LYS 295 
58  1 Y 1 A LYS 296 ? A LYS 296 
59  1 Y 1 A GLY 297 ? A GLY 297 
60  1 Y 1 A ILE 298 ? A ILE 298 
61  1 Y 1 A LEU 299 ? A LEU 299 
62  1 Y 1 A PRO 300 ? A PRO 300 
63  1 Y 1 A GLU 301 ? A GLU 301 
64  1 Y 1 A GLY 302 ? A GLY 302 
65  1 Y 1 A GLU 443 ? A GLU 443 
66  1 Y 1 A ASN 444 ? A ASN 444 
67  1 Y 1 A LEU 445 ? A LEU 445 
68  1 Y 1 A TYR 446 ? A TYR 446 
69  1 Y 1 A PHE 447 ? A PHE 447 
70  1 Y 1 A GLN 448 ? A GLN 448 
71  1 Y 1 A GLY 449 ? A GLY 449 
72  1 Y 1 A HIS 450 ? A HIS 450 
73  1 Y 1 A HIS 451 ? A HIS 451 
74  1 Y 1 A HIS 452 ? A HIS 452 
75  1 Y 1 A HIS 453 ? A HIS 453 
76  1 Y 1 A HIS 454 ? A HIS 454 
77  1 Y 1 A HIS 455 ? A HIS 455 
78  1 Y 1 B MET 1   ? B MET 1   
79  1 Y 1 B ASP 2   ? B ASP 2   
80  1 Y 1 B ASN 3   ? B ASN 3   
81  1 Y 1 B GLN 4   ? B GLN 4   
82  1 Y 1 B LYS 5   ? B LYS 5   
83  1 Y 1 B GLY 6   ? B GLY 6   
84  1 Y 1 B ARG 7   ? B ARG 7   
85  1 Y 1 B LEU 66  ? B LEU 66  
86  1 Y 1 B PRO 67  ? B PRO 67  
87  1 Y 1 B SER 68  ? B SER 68  
88  1 Y 1 B SER 69  ? B SER 69  
89  1 Y 1 B PRO 70  ? B PRO 70  
90  1 Y 1 B ASP 71  ? B ASP 71  
91  1 Y 1 B LEU 72  ? B LEU 72  
92  1 Y 1 B PRO 73  ? B PRO 73  
93  1 Y 1 B PRO 74  ? B PRO 74  
94  1 Y 1 B HIS 75  ? B HIS 75  
95  1 Y 1 B TYR 76  ? B TYR 76  
96  1 Y 1 B HIS 77  ? B HIS 77  
97  1 Y 1 B THR 78  ? B THR 78  
98  1 Y 1 B THR 79  ? B THR 79  
99  1 Y 1 B ASN 80  ? B ASN 80  
100 1 Y 1 B GLY 81  ? B GLY 81  
101 1 Y 1 B LEU 82  ? B LEU 82  
102 1 Y 1 B PRO 83  ? B PRO 83  
103 1 Y 1 B SER 84  ? B SER 84  
104 1 Y 1 B HIS 85  ? B HIS 85  
105 1 Y 1 B LEU 86  ? B LEU 86  
106 1 Y 1 B MET 87  ? B MET 87  
107 1 Y 1 B LEU 88  ? B LEU 88  
108 1 Y 1 B PRO 89  ? B PRO 89  
109 1 Y 1 B LEU 90  ? B LEU 90  
110 1 Y 1 B ASN 168 ? B ASN 168 
111 1 Y 1 B ILE 169 ? B ILE 169 
112 1 Y 1 B ILE 170 ? B ILE 170 
113 1 Y 1 B PRO 171 ? B PRO 171 
114 1 Y 1 B GLU 172 ? B GLU 172 
115 1 Y 1 B PRO 173 ? B PRO 173 
116 1 Y 1 B PRO 174 ? B PRO 174 
117 1 Y 1 B SER 175 ? B SER 175 
118 1 Y 1 B ALA 176 ? B ALA 176 
119 1 Y 1 B ASP 177 ? B ASP 177 
120 1 Y 1 B GLN 228 ? B GLN 228 
121 1 Y 1 B ASP 229 ? B ASP 229 
122 1 Y 1 B PRO 230 ? B PRO 230 
123 1 Y 1 B MET 231 ? B MET 231 
124 1 Y 1 B GLY 232 ? B GLY 232 
125 1 Y 1 B HIS 233 ? B HIS 233 
126 1 Y 1 B ASN 234 ? B ASN 234 
127 1 Y 1 B GLU 235 ? B GLU 235 
128 1 Y 1 B ARG 289 ? B ARG 289 
129 1 Y 1 B LEU 290 ? B LEU 290 
130 1 Y 1 B ILE 291 ? B ILE 291 
131 1 Y 1 B GLU 292 ? B GLU 292 
132 1 Y 1 B GLY 293 ? B GLY 293 
133 1 Y 1 B GLU 294 ? B GLU 294 
134 1 Y 1 B LYS 295 ? B LYS 295 
135 1 Y 1 B LYS 296 ? B LYS 296 
136 1 Y 1 B GLY 297 ? B GLY 297 
137 1 Y 1 B ILE 298 ? B ILE 298 
138 1 Y 1 B LEU 299 ? B LEU 299 
139 1 Y 1 B PRO 300 ? B PRO 300 
140 1 Y 1 B GLU 301 ? B GLU 301 
141 1 Y 1 B GLY 302 ? B GLY 302 
142 1 Y 1 B GLU 443 ? B GLU 443 
143 1 Y 1 B ASN 444 ? B ASN 444 
144 1 Y 1 B LEU 445 ? B LEU 445 
145 1 Y 1 B TYR 446 ? B TYR 446 
146 1 Y 1 B PHE 447 ? B PHE 447 
147 1 Y 1 B GLN 448 ? B GLN 448 
148 1 Y 1 B GLY 449 ? B GLY 449 
149 1 Y 1 B HIS 450 ? B HIS 450 
150 1 Y 1 B HIS 451 ? B HIS 451 
151 1 Y 1 B HIS 452 ? B HIS 452 
152 1 Y 1 B HIS 453 ? B HIS 453 
153 1 Y 1 B HIS 454 ? B HIS 454 
154 1 Y 1 B HIS 455 ? B HIS 455 
155 1 Y 1 C MET 1   ? C MET 1   
156 1 Y 1 C ASP 2   ? C ASP 2   
157 1 Y 1 C ASN 3   ? C ASN 3   
158 1 Y 1 C GLN 4   ? C GLN 4   
159 1 Y 1 C LYS 5   ? C LYS 5   
160 1 Y 1 C GLY 6   ? C GLY 6   
161 1 Y 1 C ARG 7   ? C ARG 7   
162 1 Y 1 C LEU 66  ? C LEU 66  
163 1 Y 1 C PRO 67  ? C PRO 67  
164 1 Y 1 C SER 68  ? C SER 68  
165 1 Y 1 C SER 69  ? C SER 69  
166 1 Y 1 C PRO 70  ? C PRO 70  
167 1 Y 1 C ASP 71  ? C ASP 71  
168 1 Y 1 C LEU 72  ? C LEU 72  
169 1 Y 1 C PRO 73  ? C PRO 73  
170 1 Y 1 C PRO 74  ? C PRO 74  
171 1 Y 1 C HIS 75  ? C HIS 75  
172 1 Y 1 C TYR 76  ? C TYR 76  
173 1 Y 1 C HIS 77  ? C HIS 77  
174 1 Y 1 C THR 78  ? C THR 78  
175 1 Y 1 C THR 79  ? C THR 79  
176 1 Y 1 C ASN 80  ? C ASN 80  
177 1 Y 1 C GLY 81  ? C GLY 81  
178 1 Y 1 C LEU 82  ? C LEU 82  
179 1 Y 1 C PRO 83  ? C PRO 83  
180 1 Y 1 C SER 84  ? C SER 84  
181 1 Y 1 C HIS 85  ? C HIS 85  
182 1 Y 1 C LEU 86  ? C LEU 86  
183 1 Y 1 C MET 87  ? C MET 87  
184 1 Y 1 C LEU 88  ? C LEU 88  
185 1 Y 1 C PRO 89  ? C PRO 89  
186 1 Y 1 C LEU 90  ? C LEU 90  
187 1 Y 1 C ASN 168 ? C ASN 168 
188 1 Y 1 C ILE 169 ? C ILE 169 
189 1 Y 1 C ILE 170 ? C ILE 170 
190 1 Y 1 C PRO 171 ? C PRO 171 
191 1 Y 1 C GLU 172 ? C GLU 172 
192 1 Y 1 C PRO 173 ? C PRO 173 
193 1 Y 1 C PRO 174 ? C PRO 174 
194 1 Y 1 C SER 175 ? C SER 175 
195 1 Y 1 C ALA 176 ? C ALA 176 
196 1 Y 1 C ASP 177 ? C ASP 177 
197 1 Y 1 C GLN 228 ? C GLN 228 
198 1 Y 1 C ASP 229 ? C ASP 229 
199 1 Y 1 C PRO 230 ? C PRO 230 
200 1 Y 1 C MET 231 ? C MET 231 
201 1 Y 1 C GLY 232 ? C GLY 232 
202 1 Y 1 C HIS 233 ? C HIS 233 
203 1 Y 1 C ASN 234 ? C ASN 234 
204 1 Y 1 C GLU 235 ? C GLU 235 
205 1 Y 1 C ARG 289 ? C ARG 289 
206 1 Y 1 C LEU 290 ? C LEU 290 
207 1 Y 1 C ILE 291 ? C ILE 291 
208 1 Y 1 C GLU 292 ? C GLU 292 
209 1 Y 1 C GLY 293 ? C GLY 293 
210 1 Y 1 C GLU 294 ? C GLU 294 
211 1 Y 1 C LYS 295 ? C LYS 295 
212 1 Y 1 C LYS 296 ? C LYS 296 
213 1 Y 1 C GLY 297 ? C GLY 297 
214 1 Y 1 C ILE 298 ? C ILE 298 
215 1 Y 1 C LEU 299 ? C LEU 299 
216 1 Y 1 C PRO 300 ? C PRO 300 
217 1 Y 1 C GLU 301 ? C GLU 301 
218 1 Y 1 C GLY 302 ? C GLY 302 
219 1 Y 1 C GLU 443 ? C GLU 443 
220 1 Y 1 C ASN 444 ? C ASN 444 
221 1 Y 1 C LEU 445 ? C LEU 445 
222 1 Y 1 C TYR 446 ? C TYR 446 
223 1 Y 1 C PHE 447 ? C PHE 447 
224 1 Y 1 C GLN 448 ? C GLN 448 
225 1 Y 1 C GLY 449 ? C GLY 449 
226 1 Y 1 C HIS 450 ? C HIS 450 
227 1 Y 1 C HIS 451 ? C HIS 451 
228 1 Y 1 C HIS 452 ? C HIS 452 
229 1 Y 1 C HIS 453 ? C HIS 453 
230 1 Y 1 C HIS 454 ? C HIS 454 
231 1 Y 1 C HIS 455 ? C HIS 455 
232 1 Y 1 D MET 1   ? D MET 1   
233 1 Y 1 D ASP 2   ? D ASP 2   
234 1 Y 1 D ASN 3   ? D ASN 3   
235 1 Y 1 D GLN 4   ? D GLN 4   
236 1 Y 1 D LYS 5   ? D LYS 5   
237 1 Y 1 D GLY 6   ? D GLY 6   
238 1 Y 1 D ARG 7   ? D ARG 7   
239 1 Y 1 D LEU 66  ? D LEU 66  
240 1 Y 1 D PRO 67  ? D PRO 67  
241 1 Y 1 D SER 68  ? D SER 68  
242 1 Y 1 D SER 69  ? D SER 69  
243 1 Y 1 D PRO 70  ? D PRO 70  
244 1 Y 1 D ASP 71  ? D ASP 71  
245 1 Y 1 D LEU 72  ? D LEU 72  
246 1 Y 1 D PRO 73  ? D PRO 73  
247 1 Y 1 D PRO 74  ? D PRO 74  
248 1 Y 1 D HIS 75  ? D HIS 75  
249 1 Y 1 D TYR 76  ? D TYR 76  
250 1 Y 1 D HIS 77  ? D HIS 77  
251 1 Y 1 D THR 78  ? D THR 78  
252 1 Y 1 D THR 79  ? D THR 79  
253 1 Y 1 D ASN 80  ? D ASN 80  
254 1 Y 1 D GLY 81  ? D GLY 81  
255 1 Y 1 D LEU 82  ? D LEU 82  
256 1 Y 1 D PRO 83  ? D PRO 83  
257 1 Y 1 D SER 84  ? D SER 84  
258 1 Y 1 D HIS 85  ? D HIS 85  
259 1 Y 1 D LEU 86  ? D LEU 86  
260 1 Y 1 D MET 87  ? D MET 87  
261 1 Y 1 D LEU 88  ? D LEU 88  
262 1 Y 1 D PRO 89  ? D PRO 89  
263 1 Y 1 D LEU 90  ? D LEU 90  
264 1 Y 1 D ASN 168 ? D ASN 168 
265 1 Y 1 D ILE 169 ? D ILE 169 
266 1 Y 1 D ILE 170 ? D ILE 170 
267 1 Y 1 D PRO 171 ? D PRO 171 
268 1 Y 1 D GLU 172 ? D GLU 172 
269 1 Y 1 D PRO 173 ? D PRO 173 
270 1 Y 1 D PRO 174 ? D PRO 174 
271 1 Y 1 D SER 175 ? D SER 175 
272 1 Y 1 D ALA 176 ? D ALA 176 
273 1 Y 1 D ASP 177 ? D ASP 177 
274 1 Y 1 D GLN 228 ? D GLN 228 
275 1 Y 1 D ASP 229 ? D ASP 229 
276 1 Y 1 D PRO 230 ? D PRO 230 
277 1 Y 1 D MET 231 ? D MET 231 
278 1 Y 1 D GLY 232 ? D GLY 232 
279 1 Y 1 D HIS 233 ? D HIS 233 
280 1 Y 1 D ASN 234 ? D ASN 234 
281 1 Y 1 D GLU 235 ? D GLU 235 
282 1 Y 1 D ARG 289 ? D ARG 289 
283 1 Y 1 D LEU 290 ? D LEU 290 
284 1 Y 1 D ILE 291 ? D ILE 291 
285 1 Y 1 D GLU 292 ? D GLU 292 
286 1 Y 1 D GLY 293 ? D GLY 293 
287 1 Y 1 D GLU 294 ? D GLU 294 
288 1 Y 1 D LYS 295 ? D LYS 295 
289 1 Y 1 D LYS 296 ? D LYS 296 
290 1 Y 1 D GLY 297 ? D GLY 297 
291 1 Y 1 D ILE 298 ? D ILE 298 
292 1 Y 1 D LEU 299 ? D LEU 299 
293 1 Y 1 D PRO 300 ? D PRO 300 
294 1 Y 1 D GLU 301 ? D GLU 301 
295 1 Y 1 D GLY 302 ? D GLY 302 
296 1 Y 1 D GLU 443 ? D GLU 443 
297 1 Y 1 D ASN 444 ? D ASN 444 
298 1 Y 1 D LEU 445 ? D LEU 445 
299 1 Y 1 D TYR 446 ? D TYR 446 
300 1 Y 1 D PHE 447 ? D PHE 447 
301 1 Y 1 D GLN 448 ? D GLN 448 
302 1 Y 1 D GLY 449 ? D GLY 449 
303 1 Y 1 D HIS 450 ? D HIS 450 
304 1 Y 1 D HIS 451 ? D HIS 451 
305 1 Y 1 D HIS 452 ? D HIS 452 
306 1 Y 1 D HIS 453 ? D HIS 453 
307 1 Y 1 D HIS 454 ? D HIS 454 
308 1 Y 1 D HIS 455 ? D HIS 455 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6jem 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8JZQ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021282 
_atom_sites.fract_transf_matrix[1][2]   0.001396 
_atom_sites.fract_transf_matrix[1][3]   0.000096 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012390 
_atom_sites.fract_transf_matrix[2][3]   0.000860 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007932 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1     N N   . ILE A 1 8   ? 0.651   -13.421 11.287  1.00 55.64  ? 8   ILE A N   1 
ATOM 2     C CA  . ILE A 1 8   ? 1.497   -12.525 10.508  1.00 59.24  ? 8   ILE A CA  1 
ATOM 3     C C   . ILE A 1 8   ? 2.391   -13.315 9.549   1.00 59.43  ? 8   ILE A C   1 
ATOM 4     O O   . ILE A 1 8   ? 2.576   -12.915 8.403   1.00 65.56  ? 8   ILE A O   1 
ATOM 5     C CB  . ILE A 1 8   ? 2.344   -11.622 11.432  1.00 62.95  ? 8   ILE A CB  1 
ATOM 6     C CG1 . ILE A 1 8   ? 1.441   -10.831 12.384  1.00 56.57  ? 8   ILE A CG1 1 
ATOM 7     C CG2 . ILE A 1 8   ? 3.201   -10.668 10.612  1.00 69.39  ? 8   ILE A CG2 1 
ATOM 8     C CD1 . ILE A 1 8   ? 0.504   -9.868  11.684  1.00 55.79  ? 8   ILE A CD1 1 
ATOM 9     N N   . SER A 1 9   ? 2.938   -14.436 10.013  1.00 54.15  ? 9   SER A N   1 
ATOM 10    C CA  . SER A 1 9   ? 3.823   -15.262 9.202   1.00 51.71  ? 9   SER A CA  1 
ATOM 11    C C   . SER A 1 9   ? 3.053   -16.411 8.567   1.00 48.75  ? 9   SER A C   1 
ATOM 12    O O   . SER A 1 9   ? 2.248   -17.077 9.228   1.00 47.18  ? 9   SER A O   1 
ATOM 13    C CB  . SER A 1 9   ? 4.977   -15.820 10.037  1.00 51.56  ? 9   SER A CB  1 
ATOM 14    O OG  . SER A 1 9   ? 4.531   -16.869 10.877  1.00 45.14  ? 9   SER A OG  1 
ATOM 15    N N   . ILE A 1 10  ? 3.309   -16.649 7.280   1.00 40.80  ? 10  ILE A N   1 
ATOM 16    C CA  . ILE A 1 10  ? 2.620   -17.673 6.505   1.00 42.11  ? 10  ILE A CA  1 
ATOM 17    C C   . ILE A 1 10  ? 3.652   -18.515 5.766   1.00 33.47  ? 10  ILE A C   1 
ATOM 18    O O   . ILE A 1 10  ? 4.679   -17.995 5.311   1.00 42.19  ? 10  ILE A O   1 
ATOM 19    C CB  . ILE A 1 10  ? 1.615   -17.053 5.505   1.00 47.23  ? 10  ILE A CB  1 
ATOM 20    C CG1 . ILE A 1 10  ? 0.719   -16.025 6.198   1.00 46.25  ? 10  ILE A CG1 1 
ATOM 21    C CG2 . ILE A 1 10  ? 0.757   -18.132 4.859   1.00 38.62  ? 10  ILE A CG2 1 
ATOM 22    C CD1 . ILE A 1 10  ? -0.287  -15.378 5.275   1.00 38.72  ? 10  ILE A CD1 1 
ATOM 23    N N   . ALA A 1 11  ? 3.379   -19.813 5.648   1.00 25.55  ? 11  ALA A N   1 
ATOM 24    C CA  . ALA A 1 11  ? 4.205   -20.740 4.888   1.00 29.56  ? 11  ALA A CA  1 
ATOM 25    C C   . ALA A 1 11  ? 3.371   -21.370 3.782   1.00 33.57  ? 11  ALA A C   1 
ATOM 26    O O   . ALA A 1 11  ? 2.224   -21.767 4.007   1.00 45.61  ? 11  ALA A O   1 
ATOM 27    C CB  . ALA A 1 11  ? 4.792   -21.830 5.793   1.00 30.27  ? 11  ALA A CB  1 
ATOM 28    N N   . LEU A 1 12  ? 3.947   -21.459 2.586   1.00 35.53  ? 12  LEU A N   1 
ATOM 29    C CA  . LEU A 1 12  ? 3.260   -21.963 1.406   1.00 37.76  ? 12  LEU A CA  1 
ATOM 30    C C   . LEU A 1 12  ? 3.928   -23.243 0.929   1.00 38.14  ? 12  LEU A C   1 
ATOM 31    O O   . LEU A 1 12  ? 5.160   -23.313 0.835   1.00 42.14  ? 12  LEU A O   1 
ATOM 32    C CB  . LEU A 1 12  ? 3.256   -20.922 0.280   1.00 29.57  ? 12  LEU A CB  1 
ATOM 33    C CG  . LEU A 1 12  ? 1.998   -20.060 0.161   1.00 35.45  ? 12  LEU A CG  1 
ATOM 34    C CD1 . LEU A 1 12  ? 1.709   -19.359 1.473   1.00 41.50  ? 12  LEU A CD1 1 
ATOM 35    C CD2 . LEU A 1 12  ? 2.130   -19.053 -0.971  1.00 41.90  ? 12  LEU A CD2 1 
ATOM 36    N N   . LEU A 1 13  ? 3.111   -24.254 0.638   1.00 35.37  ? 13  LEU A N   1 
ATOM 37    C CA  . LEU A 1 13  ? 3.579   -25.550 0.151   1.00 33.13  ? 13  LEU A CA  1 
ATOM 38    C C   . LEU A 1 13  ? 2.795   -25.900 -1.108  1.00 42.63  ? 13  LEU A C   1 
ATOM 39    O O   . LEU A 1 13  ? 1.804   -26.641 -1.053  1.00 46.58  ? 13  LEU A O   1 
ATOM 40    C CB  . LEU A 1 13  ? 3.421   -26.635 1.215   1.00 28.46  ? 13  LEU A CB  1 
ATOM 41    C CG  . LEU A 1 13  ? 3.923   -28.028 0.838   1.00 35.04  ? 13  LEU A CG  1 
ATOM 42    C CD1 . LEU A 1 13  ? 5.434   -28.127 1.010   1.00 44.38  ? 13  LEU A CD1 1 
ATOM 43    C CD2 . LEU A 1 13  ? 3.207   -29.093 1.653   1.00 42.82  ? 13  LEU A CD2 1 
ATOM 44    N N   . PRO A 1 14  ? 3.206   -25.372 -2.257  1.00 40.50  ? 14  PRO A N   1 
ATOM 45    C CA  . PRO A 1 14  ? 2.568   -25.764 -3.518  1.00 36.20  ? 14  PRO A CA  1 
ATOM 46    C C   . PRO A 1 14  ? 2.953   -27.183 -3.905  1.00 47.55  ? 14  PRO A C   1 
ATOM 47    O O   . PRO A 1 14  ? 3.770   -27.842 -3.259  1.00 56.23  ? 14  PRO A O   1 
ATOM 48    C CB  . PRO A 1 14  ? 3.112   -24.745 -4.520  1.00 44.55  ? 14  PRO A CB  1 
ATOM 49    C CG  . PRO A 1 14  ? 4.425   -24.326 -3.943  1.00 36.68  ? 14  PRO A CG  1 
ATOM 50    C CD  . PRO A 1 14  ? 4.246   -24.350 -2.455  1.00 48.00  ? 14  PRO A CD  1 
ATOM 51    N N   . PHE A 1 15  ? 2.344   -27.655 -4.986  1.00 48.78  ? 15  PHE A N   1 
ATOM 52    C CA  . PHE A 1 15  ? 2.675   -28.970 -5.507  1.00 49.26  ? 15  PHE A CA  1 
ATOM 53    C C   . PHE A 1 15  ? 3.854   -28.872 -6.475  1.00 59.00  ? 15  PHE A C   1 
ATOM 54    O O   . PHE A 1 15  ? 4.272   -27.784 -6.884  1.00 62.91  ? 15  PHE A O   1 
ATOM 55    C CB  . PHE A 1 15  ? 1.458   -29.605 -6.180  1.00 45.15  ? 15  PHE A CB  1 
ATOM 56    C CG  . PHE A 1 15  ? 1.611   -31.074 -6.437  1.00 48.81  ? 15  PHE A CG  1 
ATOM 57    C CD1 . PHE A 1 15  ? 2.147   -31.905 -5.466  1.00 56.32  ? 15  PHE A CD1 1 
ATOM 58    C CD2 . PHE A 1 15  ? 1.219   -31.626 -7.642  1.00 53.80  ? 15  PHE A CD2 1 
ATOM 59    C CE1 . PHE A 1 15  ? 2.296   -33.259 -5.698  1.00 60.30  ? 15  PHE A CE1 1 
ATOM 60    C CE2 . PHE A 1 15  ? 1.360   -32.981 -7.879  1.00 54.46  ? 15  PHE A CE2 1 
ATOM 61    C CZ  . PHE A 1 15  ? 1.901   -33.798 -6.906  1.00 61.31  ? 15  PHE A CZ  1 
ATOM 62    N N   . LEU A 1 16  ? 4.399   -30.030 -6.838  1.00 65.69  ? 16  LEU A N   1 
ATOM 63    C CA  . LEU A 1 16  ? 5.604   -30.101 -7.666  1.00 67.10  ? 16  LEU A CA  1 
ATOM 64    C C   . LEU A 1 16  ? 5.252   -30.018 -9.152  1.00 68.72  ? 16  LEU A C   1 
ATOM 65    O O   . LEU A 1 16  ? 5.476   -30.942 -9.935  1.00 71.33  ? 16  LEU A O   1 
ATOM 66    C CB  . LEU A 1 16  ? 6.388   -31.368 -7.349  1.00 65.03  ? 16  LEU A CB  1 
ATOM 67    C CG  . LEU A 1 16  ? 7.524   -31.203 -6.341  1.00 52.99  ? 16  LEU A CG  1 
ATOM 68    C CD1 . LEU A 1 16  ? 7.077   -30.365 -5.157  1.00 59.96  ? 16  LEU A CD1 1 
ATOM 69    C CD2 . LEU A 1 16  ? 8.020   -32.562 -5.881  1.00 57.38  ? 16  LEU A CD2 1 
ATOM 70    N N   . ALA A 1 17  ? 4.695   -28.874 -9.530  1.00 72.10  ? 17  ALA A N   1 
ATOM 71    C CA  . ALA A 1 17  ? 4.338   -28.611 -10.915 1.00 68.02  ? 17  ALA A CA  1 
ATOM 72    C C   . ALA A 1 17  ? 4.365   -27.108 -11.136 1.00 72.02  ? 17  ALA A C   1 
ATOM 73    O O   . ALA A 1 17  ? 3.801   -26.353 -10.338 1.00 71.37  ? 17  ALA A O   1 
ATOM 74    C CB  . ALA A 1 17  ? 2.955   -29.181 -11.248 1.00 66.93  ? 17  ALA A CB  1 
ATOM 75    N N   . HIS A 1 18  ? 5.022   -26.683 -12.217 1.00 76.99  ? 18  HIS A N   1 
ATOM 76    C CA  . HIS A 1 18  ? 5.139   -25.257 -12.500 1.00 82.99  ? 18  HIS A CA  1 
ATOM 77    C C   . HIS A 1 18  ? 3.788   -24.601 -12.750 1.00 78.69  ? 18  HIS A C   1 
ATOM 78    O O   . HIS A 1 18  ? 3.678   -23.374 -12.647 1.00 76.24  ? 18  HIS A O   1 
ATOM 79    C CB  . HIS A 1 18  ? 6.071   -25.035 -13.693 1.00 89.73  ? 18  HIS A CB  1 
ATOM 80    C CG  . HIS A 1 18  ? 7.504   -25.350 -13.401 1.00 98.34  ? 18  HIS A CG  1 
ATOM 81    N ND1 . HIS A 1 18  ? 8.146   -26.455 -13.918 1.00 97.88  ? 18  HIS A ND1 1 
ATOM 82    C CD2 . HIS A 1 18  ? 8.415   -24.714 -12.626 1.00 91.07  ? 18  HIS A CD2 1 
ATOM 83    C CE1 . HIS A 1 18  ? 9.394   -26.478 -13.486 1.00 93.94  ? 18  HIS A CE1 1 
ATOM 84    N NE2 . HIS A 1 18  ? 9.583   -25.431 -12.699 1.00 92.98  ? 18  HIS A NE2 1 
ATOM 85    N N   . GLY A 1 19  ? 2.757   -25.388 -13.072 1.00 76.83  ? 19  GLY A N   1 
ATOM 86    C CA  . GLY A 1 19  ? 1.414   -24.844 -13.153 1.00 78.86  ? 19  GLY A CA  1 
ATOM 87    C C   . GLY A 1 19  ? 0.852   -24.404 -11.816 1.00 79.07  ? 19  GLY A C   1 
ATOM 88    O O   . GLY A 1 19  ? -0.090  -23.605 -11.784 1.00 79.60  ? 19  GLY A O   1 
ATOM 89    N N   . HIS A 1 20  ? 1.405   -24.911 -10.712 1.00 66.41  ? 20  HIS A N   1 
ATOM 90    C CA  . HIS A 1 20  ? 0.995   -24.497 -9.379  1.00 63.95  ? 20  HIS A CA  1 
ATOM 91    C C   . HIS A 1 20  ? 2.044   -23.664 -8.660  1.00 64.32  ? 20  HIS A C   1 
ATOM 92    O O   . HIS A 1 20  ? 1.722   -23.044 -7.639  1.00 59.18  ? 20  HIS A O   1 
ATOM 93    C CB  . HIS A 1 20  ? 0.644   -25.721 -8.519  1.00 57.53  ? 20  HIS A CB  1 
ATOM 94    C CG  . HIS A 1 20  ? -0.559  -26.471 -8.998  1.00 63.39  ? 20  HIS A CG  1 
ATOM 95    N ND1 . HIS A 1 20  ? -0.556  -27.224 -10.154 1.00 61.06  ? 20  HIS A ND1 1 
ATOM 96    C CD2 . HIS A 1 20  ? -1.807  -26.578 -8.484  1.00 52.22  ? 20  HIS A CD2 1 
ATOM 97    C CE1 . HIS A 1 20  ? -1.749  -27.767 -10.326 1.00 64.00  ? 20  HIS A CE1 1 
ATOM 98    N NE2 . HIS A 1 20  ? -2.526  -27.391 -9.326  1.00 55.17  ? 20  HIS A NE2 1 
ATOM 99    N N   . ILE A 1 21  ? 3.282   -23.630 -9.158  1.00 65.97  ? 21  ILE A N   1 
ATOM 100   C CA  . ILE A 1 21  ? 4.307   -22.810 -8.527  1.00 52.98  ? 21  ILE A CA  1 
ATOM 101   C C   . ILE A 1 21  ? 4.057   -21.333 -8.805  1.00 53.94  ? 21  ILE A C   1 
ATOM 102   O O   . ILE A 1 21  ? 4.251   -20.479 -7.932  1.00 54.47  ? 21  ILE A O   1 
ATOM 103   C CB  . ILE A 1 21  ? 5.705   -23.248 -9.001  1.00 53.69  ? 21  ILE A CB  1 
ATOM 104   C CG1 . ILE A 1 21  ? 5.996   -24.676 -8.544  1.00 61.82  ? 21  ILE A CG1 1 
ATOM 105   C CG2 . ILE A 1 21  ? 6.769   -22.306 -8.469  1.00 48.98  ? 21  ILE A CG2 1 
ATOM 106   C CD1 . ILE A 1 21  ? 6.209   -24.799 -7.052  1.00 66.87  ? 21  ILE A CD1 1 
ATOM 107   N N   . SER A 1 22  ? 3.615   -21.003 -10.024 1.00 44.59  ? 22  SER A N   1 
ATOM 108   C CA  . SER A 1 22  ? 3.380   -19.599 -10.358 1.00 46.86  ? 22  SER A CA  1 
ATOM 109   C C   . SER A 1 22  ? 2.240   -18.989 -9.550  1.00 41.63  ? 22  SER A C   1 
ATOM 110   O O   . SER A 1 22  ? 2.428   -17.893 -8.995  1.00 36.69  ? 22  SER A O   1 
ATOM 111   C CB  . SER A 1 22  ? 3.152   -19.450 -11.866 1.00 47.80  ? 22  SER A CB  1 
ATOM 112   O OG  . SER A 1 22  ? 4.282   -19.888 -12.595 1.00 67.72  ? 22  SER A OG  1 
ATOM 113   N N   . PRO A 1 23  ? 1.053   -19.605 -9.448  1.00 42.89  ? 23  PRO A N   1 
ATOM 114   C CA  . PRO A 1 23  ? 0.000   -18.976 -8.631  1.00 46.04  ? 23  PRO A CA  1 
ATOM 115   C C   . PRO A 1 23  ? 0.392   -18.826 -7.170  1.00 44.77  ? 23  PRO A C   1 
ATOM 116   O O   . PRO A 1 23  ? 0.110   -17.786 -6.562  1.00 43.54  ? 23  PRO A O   1 
ATOM 117   C CB  . PRO A 1 23  ? -1.195  -19.921 -8.809  1.00 44.22  ? 23  PRO A CB  1 
ATOM 118   C CG  . PRO A 1 23  ? -0.928  -20.639 -10.082 1.00 47.13  ? 23  PRO A CG  1 
ATOM 119   C CD  . PRO A 1 23  ? 0.555   -20.820 -10.117 1.00 45.74  ? 23  PRO A CD  1 
ATOM 120   N N   . PHE A 1 24  ? 1.048   -19.836 -6.590  1.00 36.30  ? 24  PHE A N   1 
ATOM 121   C CA  . PHE A 1 24  ? 1.508   -19.722 -5.211  1.00 37.31  ? 24  PHE A CA  1 
ATOM 122   C C   . PHE A 1 24  ? 2.531   -18.604 -5.057  1.00 41.77  ? 24  PHE A C   1 
ATOM 123   O O   . PHE A 1 24  ? 2.490   -17.849 -4.079  1.00 37.56  ? 24  PHE A O   1 
ATOM 124   C CB  . PHE A 1 24  ? 2.095   -21.054 -4.743  1.00 41.53  ? 24  PHE A CB  1 
ATOM 125   C CG  . PHE A 1 24  ? 1.080   -21.985 -4.138  1.00 40.42  ? 24  PHE A CG  1 
ATOM 126   C CD1 . PHE A 1 24  ? 0.216   -22.710 -4.939  1.00 42.79  ? 24  PHE A CD1 1 
ATOM 127   C CD2 . PHE A 1 24  ? 0.999   -22.135 -2.764  1.00 32.16  ? 24  PHE A CD2 1 
ATOM 128   C CE1 . PHE A 1 24  ? -0.714  -23.567 -4.382  1.00 32.85  ? 24  PHE A CE1 1 
ATOM 129   C CE2 . PHE A 1 24  ? 0.070   -22.989 -2.199  1.00 36.94  ? 24  PHE A CE2 1 
ATOM 130   C CZ  . PHE A 1 24  ? -0.786  -23.708 -3.011  1.00 36.11  ? 24  PHE A CZ  1 
ATOM 131   N N   . PHE A 1 25  ? 3.449   -18.467 -6.019  1.00 45.56  ? 25  PHE A N   1 
ATOM 132   C CA  . PHE A 1 25  ? 4.463   -17.420 -5.927  1.00 46.21  ? 25  PHE A CA  1 
ATOM 133   C C   . PHE A 1 25  ? 3.849   -16.035 -6.068  1.00 45.40  ? 25  PHE A C   1 
ATOM 134   O O   . PHE A 1 25  ? 4.256   -15.093 -5.375  1.00 45.00  ? 25  PHE A O   1 
ATOM 135   C CB  . PHE A 1 25  ? 5.541   -17.639 -6.987  1.00 45.53  ? 25  PHE A CB  1 
ATOM 136   C CG  . PHE A 1 25  ? 6.544   -16.525 -7.070  1.00 49.69  ? 25  PHE A CG  1 
ATOM 137   C CD1 . PHE A 1 25  ? 7.314   -16.187 -5.968  1.00 49.25  ? 25  PHE A CD1 1 
ATOM 138   C CD2 . PHE A 1 25  ? 6.725   -15.820 -8.248  1.00 53.41  ? 25  PHE A CD2 1 
ATOM 139   C CE1 . PHE A 1 25  ? 8.239   -15.163 -6.038  1.00 54.10  ? 25  PHE A CE1 1 
ATOM 140   C CE2 . PHE A 1 25  ? 7.655   -14.798 -8.327  1.00 52.90  ? 25  PHE A CE2 1 
ATOM 141   C CZ  . PHE A 1 25  ? 8.412   -14.470 -7.218  1.00 53.93  ? 25  PHE A CZ  1 
ATOM 142   N N   . GLU A 1 26  ? 2.867   -15.888 -6.958  1.00 47.98  ? 26  GLU A N   1 
ATOM 143   C CA  . GLU A 1 26  ? 2.207   -14.597 -7.109  1.00 51.11  ? 26  GLU A CA  1 
ATOM 144   C C   . GLU A 1 26  ? 1.382   -14.254 -5.875  1.00 55.03  ? 26  GLU A C   1 
ATOM 145   O O   . GLU A 1 26  ? 1.360   -13.097 -5.439  1.00 59.06  ? 26  GLU A O   1 
ATOM 146   C CB  . GLU A 1 26  ? 1.336   -14.593 -8.367  1.00 50.61  ? 26  GLU A CB  1 
ATOM 147   C CG  . GLU A 1 26  ? 2.135   -14.614 -9.665  1.00 51.64  ? 26  GLU A CG  1 
ATOM 148   C CD  . GLU A 1 26  ? 2.993   -13.374 -9.847  1.00 53.07  ? 26  GLU A CD  1 
ATOM 149   O OE1 . GLU A 1 26  ? 2.634   -12.311 -9.294  1.00 55.35  ? 26  GLU A OE1 1 
ATOM 150   O OE2 . GLU A 1 26  ? 4.028   -13.458 -10.542 1.00 59.41  ? 26  GLU A OE2 1 
ATOM 151   N N   . LEU A 1 27  ? 0.706   -15.248 -5.291  1.00 49.85  ? 27  LEU A N   1 
ATOM 152   C CA  . LEU A 1 27  ? 0.019   -15.018 -4.024  1.00 45.62  ? 27  LEU A CA  1 
ATOM 153   C C   . LEU A 1 27  ? 1.005   -14.632 -2.933  1.00 48.50  ? 27  LEU A C   1 
ATOM 154   O O   . LEU A 1 27  ? 0.693   -13.803 -2.071  1.00 54.19  ? 27  LEU A O   1 
ATOM 155   C CB  . LEU A 1 27  ? -0.772  -16.259 -3.616  1.00 46.53  ? 27  LEU A CB  1 
ATOM 156   C CG  . LEU A 1 27  ? -1.577  -16.136 -2.321  1.00 50.46  ? 27  LEU A CG  1 
ATOM 157   C CD1 . LEU A 1 27  ? -2.585  -15.000 -2.416  1.00 47.29  ? 27  LEU A CD1 1 
ATOM 158   C CD2 . LEU A 1 27  ? -2.271  -17.447 -2.003  1.00 44.44  ? 27  LEU A CD2 1 
ATOM 159   N N   . ALA A 1 28  ? 2.200   -15.224 -2.950  1.00 45.03  ? 28  ALA A N   1 
ATOM 160   C CA  . ALA A 1 28  ? 3.233   -14.846 -1.993  1.00 42.10  ? 28  ALA A CA  1 
ATOM 161   C C   . ALA A 1 28  ? 3.622   -13.384 -2.157  1.00 44.38  ? 28  ALA A C   1 
ATOM 162   O O   . ALA A 1 28  ? 3.708   -12.635 -1.179  1.00 52.29  ? 28  ALA A O   1 
ATOM 163   C CB  . ALA A 1 28  ? 4.456   -15.751 -2.158  1.00 43.20  ? 28  ALA A CB  1 
ATOM 164   N N   . LYS A 1 29  ? 3.864   -12.962 -3.399  1.00 46.76  ? 29  LYS A N   1 
ATOM 165   C CA  . LYS A 1 29  ? 4.200   -11.563 -3.654  1.00 48.59  ? 29  LYS A CA  1 
ATOM 166   C C   . LYS A 1 29  ? 3.068   -10.633 -3.234  1.00 49.99  ? 29  LYS A C   1 
ATOM 167   O O   . LYS A 1 29  ? 3.313   -9.517  -2.764  1.00 49.72  ? 29  LYS A O   1 
ATOM 168   C CB  . LYS A 1 29  ? 4.525   -11.358 -5.133  1.00 47.74  ? 29  LYS A CB  1 
ATOM 169   C CG  . LYS A 1 29  ? 5.671   -12.207 -5.640  1.00 47.44  ? 29  LYS A CG  1 
ATOM 170   C CD  . LYS A 1 29  ? 5.780   -12.115 -7.150  1.00 50.85  ? 29  LYS A CD  1 
ATOM 171   C CE  . LYS A 1 29  ? 6.148   -10.709 -7.597  1.00 51.97  ? 29  LYS A CE  1 
ATOM 172   N NZ  . LYS A 1 29  ? 6.344   -10.637 -9.070  1.00 58.36  ? 29  LYS A NZ  1 
ATOM 173   N N   . GLN A 1 30  ? 1.818   -11.075 -3.398  1.00 52.26  ? 30  GLN A N   1 
ATOM 174   C CA  . GLN A 1 30  ? 0.690   -10.221 -3.038  1.00 54.29  ? 30  GLN A CA  1 
ATOM 175   C C   . GLN A 1 30  ? 0.519   -10.126 -1.526  1.00 51.33  ? 30  GLN A C   1 
ATOM 176   O O   . GLN A 1 30  ? 0.173   -9.061  -1.000  1.00 50.29  ? 30  GLN A O   1 
ATOM 177   C CB  . GLN A 1 30  ? -0.590  -10.736 -3.692  1.00 55.36  ? 30  GLN A CB  1 
ATOM 178   C CG  . GLN A 1 30  ? -0.613  -10.563 -5.198  1.00 58.63  ? 30  GLN A CG  1 
ATOM 179   C CD  . GLN A 1 30  ? -0.422  -9.118  -5.620  1.00 60.64  ? 30  GLN A CD  1 
ATOM 180   O OE1 . GLN A 1 30  ? -1.011  -8.205  -5.038  1.00 63.05  ? 30  GLN A OE1 1 
ATOM 181   N NE2 . GLN A 1 30  ? 0.413   -8.903  -6.632  1.00 58.11  ? 30  GLN A NE2 1 
ATOM 182   N N   . LEU A 1 31  ? 0.749   -11.222 -0.807  1.00 48.43  ? 31  LEU A N   1 
ATOM 183   C CA  . LEU A 1 31  ? 0.603   -11.181 0.640   1.00 53.06  ? 31  LEU A CA  1 
ATOM 184   C C   . LEU A 1 31  ? 1.825   -10.600 1.333   1.00 58.71  ? 31  LEU A C   1 
ATOM 185   O O   . LEU A 1 31  ? 1.739   -10.239 2.512   1.00 54.59  ? 31  LEU A O   1 
ATOM 186   C CB  . LEU A 1 31  ? 0.318   -12.580 1.189   1.00 48.32  ? 31  LEU A CB  1 
ATOM 187   C CG  . LEU A 1 31  ? -0.858  -13.373 0.612   1.00 60.29  ? 31  LEU A CG  1 
ATOM 188   C CD1 . LEU A 1 31  ? -1.116  -14.621 1.433   1.00 49.42  ? 31  LEU A CD1 1 
ATOM 189   C CD2 . LEU A 1 31  ? -2.110  -12.526 0.519   1.00 67.91  ? 31  LEU A CD2 1 
ATOM 190   N N   . ALA A 1 32  ? 2.960   -10.500 0.635   1.00 54.44  ? 32  ALA A N   1 
ATOM 191   C CA  . ALA A 1 32  ? 4.156   -9.910  1.226   1.00 43.27  ? 32  ALA A CA  1 
ATOM 192   C C   . ALA A 1 32  ? 4.155   -8.389  1.167   1.00 50.47  ? 32  ALA A C   1 
ATOM 193   O O   . ALA A 1 32  ? 4.855   -7.752  1.963   1.00 58.90  ? 32  ALA A O   1 
ATOM 194   C CB  . ALA A 1 32  ? 5.406   -10.450 0.530   1.00 46.45  ? 32  ALA A CB  1 
ATOM 195   N N   . LYS A 1 33  ? 3.391   -7.795  0.256   1.00 52.92  ? 33  LYS A N   1 
ATOM 196   C CA  . LYS A 1 33  ? 3.334   -6.346  0.131   1.00 52.20  ? 33  LYS A CA  1 
ATOM 197   C C   . LYS A 1 33  ? 2.263   -5.710  1.005   1.00 56.38  ? 33  LYS A C   1 
ATOM 198   O O   . LYS A 1 33  ? 2.190   -4.478  1.068   1.00 64.54  ? 33  LYS A O   1 
ATOM 199   C CB  . LYS A 1 33  ? 3.102   -5.956  -1.331  1.00 51.34  ? 33  LYS A CB  1 
ATOM 200   C CG  . LYS A 1 33  ? 1.899   -6.628  -1.955  1.00 59.49  ? 33  LYS A CG  1 
ATOM 201   C CD  . LYS A 1 33  ? 1.866   -6.432  -3.457  1.00 57.85  ? 33  LYS A CD  1 
ATOM 202   C CE  . LYS A 1 33  ? 1.582   -4.989  -3.823  1.00 59.68  ? 33  LYS A CE  1 
ATOM 203   N NZ  . LYS A 1 33  ? 1.435   -4.827  -5.296  1.00 49.08  ? 33  LYS A NZ  1 
ATOM 204   N N   . ARG A 1 34  ? 1.458   -6.576  1.633   1.00 61.77  ? 34  ARG A N   1 
ATOM 205   C CA  . ARG A 1 34  ? 0.363   -6.126  2.526   1.00 63.51  ? 34  ARG A CA  1 
ATOM 206   C C   . ARG A 1 34  ? 0.521   -6.806  3.882   1.00 72.56  ? 34  ARG A C   1 
ATOM 207   O O   . ARG A 1 34  ? 0.764   -8.015  3.905   1.00 78.47  ? 34  ARG A O   1 
ATOM 208   C CB  . ARG A 1 34  ? -1.009  -6.454  1.942   1.00 55.39  ? 34  ARG A CB  1 
ATOM 209   C CG  . ARG A 1 34  ? -1.187  -7.871  1.427   1.00 54.06  ? 34  ARG A CG  1 
ATOM 210   C CD  . ARG A 1 34  ? -2.490  -7.898  0.660   1.00 64.46  ? 34  ARG A CD  1 
ATOM 211   N NE  . ARG A 1 34  ? -2.664  -6.676  -0.105  1.00 56.76  ? 34  ARG A NE  1 
ATOM 212   C CZ  . ARG A 1 34  ? -2.483  -6.569  -1.413  1.00 59.94  ? 34  ARG A CZ  1 
ATOM 213   N NH1 . ARG A 1 34  ? -2.135  -7.623  -2.128  1.00 60.32  ? 34  ARG A NH1 1 
ATOM 214   N NH2 . ARG A 1 34  ? -2.662  -5.404  -2.002  1.00 70.43  ? 34  ARG A NH2 1 
ATOM 215   N N   . ASN A 1 35  ? 0.507   -6.026  4.960   1.00 78.32  ? 35  ASN A N   1 
ATOM 216   C CA  . ASN A 1 35  ? 0.623   -6.562  6.344   1.00 77.85  ? 35  ASN A CA  1 
ATOM 217   C C   . ASN A 1 35  ? 2.037   -7.088  6.541   1.00 76.22  ? 35  ASN A C   1 
ATOM 218   O O   . ASN A 1 35  ? 2.279   -7.719  7.578   1.00 75.59  ? 35  ASN A O   1 
ATOM 219   C CB  . ASN A 1 35  ? -0.514  -7.499  6.745   1.00 83.40  ? 35  ASN A CB  1 
ATOM 220   C CG  . ASN A 1 35  ? -1.595  -6.788  7.535   1.00 97.18  ? 35  ASN A CG  1 
ATOM 221   O OD1 . ASN A 1 35  ? -1.651  -5.560  7.551   1.00 91.32  ? 35  ASN A OD1 1 
ATOM 222   N ND2 . ASN A 1 35  ? -2.454  -7.547  8.193   1.00 96.53  ? 35  ASN A ND2 1 
ATOM 223   N N   . CYS A 1 36  ? 2.908   -6.875  5.557   1.00 74.64  ? 36  CYS A N   1 
ATOM 224   C CA  . CYS A 1 36  ? 4.333   -7.238  5.724   1.00 77.30  ? 36  CYS A CA  1 
ATOM 225   C C   . CYS A 1 36  ? 4.379   -8.673  6.223   1.00 76.10  ? 36  CYS A C   1 
ATOM 226   O O   . CYS A 1 36  ? 5.186   -8.963  7.122   1.00 80.95  ? 36  CYS A O   1 
ATOM 227   C CB  . CYS A 1 36  ? 5.026   -6.284  6.687   1.00 80.50  ? 36  CYS A CB  1 
ATOM 228   S SG  . CYS A 1 36  ? 4.955   -4.557  6.149   1.00 93.98  ? 36  CYS A SG  1 
ATOM 229   N N   . ASN A 1 37  ? 3.456   -9.493  5.736   1.00 67.05  ? 37  ASN A N   1 
ATOM 230   C CA  . ASN A 1 37  ? 3.395   -10.905 6.170   1.00 56.64  ? 37  ASN A CA  1 
ATOM 231   C C   . ASN A 1 37  ? 4.756   -11.537 5.923   1.00 51.46  ? 37  ASN A C   1 
ATOM 232   O O   . ASN A 1 37  ? 5.234   -11.460 4.786   1.00 51.93  ? 37  ASN A O   1 
ATOM 233   C CB  . ASN A 1 37  ? 2.257   -11.656 5.476   1.00 60.16  ? 37  ASN A CB  1 
ATOM 234   C CG  . ASN A 1 37  ? 0.886   -11.094 5.774   1.00 56.73  ? 37  ASN A CG  1 
ATOM 235   O OD1 . ASN A 1 37  ? 0.682   -10.463 6.806   1.00 75.39  ? 37  ASN A OD1 1 
ATOM 236   N ND2 . ASN A 1 37  ? -0.061  -11.333 4.885   1.00 48.25  ? 37  ASN A ND2 1 
ATOM 237   N N   . VAL A 1 38  ? 5.381   -12.077 6.975   1.00 51.84  ? 38  VAL A N   1 
ATOM 238   C CA  . VAL A 1 38  ? 6.670   -12.810 6.797   1.00 52.53  ? 38  VAL A CA  1 
ATOM 239   C C   . VAL A 1 38  ? 6.340   -14.003 5.903   1.00 48.13  ? 38  VAL A C   1 
ATOM 240   O O   . VAL A 1 38  ? 5.434   -14.774 6.271   1.00 45.40  ? 38  VAL A O   1 
ATOM 241   C CB  . VAL A 1 38  ? 7.253   -13.261 8.148   1.00 49.88  ? 38  VAL A CB  1 
ATOM 242   C CG1 . VAL A 1 38  ? 8.577   -13.991 7.982   1.00 43.44  ? 38  VAL A CG1 1 
ATOM 243   C CG2 . VAL A 1 38  ? 7.399   -12.094 9.114   1.00 56.10  ? 38  VAL A CG2 1 
ATOM 244   N N   . PHE A 1 39  ? 7.063   -14.190 4.807   1.00 52.40  ? 39  PHE A N   1 
ATOM 245   C CA  . PHE A 1 39  ? 6.622   -15.241 3.868   1.00 46.63  ? 39  PHE A CA  1 
ATOM 246   C C   . PHE A 1 39  ? 7.647   -16.343 3.683   1.00 48.50  ? 39  PHE A C   1 
ATOM 247   O O   . PHE A 1 39  ? 8.776   -16.028 3.372   1.00 55.93  ? 39  PHE A O   1 
ATOM 248   C CB  . PHE A 1 39  ? 6.198   -14.599 2.557   1.00 51.53  ? 39  PHE A CB  1 
ATOM 249   C CG  . PHE A 1 39  ? 5.011   -13.724 2.791   1.00 53.20  ? 39  PHE A CG  1 
ATOM 250   C CD1 . PHE A 1 39  ? 3.745   -14.272 2.824   1.00 55.16  ? 39  PHE A CD1 1 
ATOM 251   C CD2 . PHE A 1 39  ? 5.158   -12.355 2.847   1.00 62.69  ? 39  PHE A CD2 1 
ATOM 252   C CE1 . PHE A 1 39  ? 2.642   -13.458 2.977   1.00 61.64  ? 39  PHE A CE1 1 
ATOM 253   C CE2 . PHE A 1 39  ? 4.053   -11.547 3.020   1.00 62.43  ? 39  PHE A CE2 1 
ATOM 254   C CZ  . PHE A 1 39  ? 2.800   -12.098 3.080   1.00 58.53  ? 39  PHE A CZ  1 
ATOM 255   N N   . LEU A 1 40  ? 7.212   -17.589 3.857   1.00 38.58  ? 40  LEU A N   1 
ATOM 256   C CA  . LEU A 1 40  ? 8.114   -18.755 3.682   1.00 38.71  ? 40  LEU A CA  1 
ATOM 257   C C   . LEU A 1 40  ? 7.488   -19.653 2.610   1.00 33.99  ? 40  LEU A C   1 
ATOM 258   O O   . LEU A 1 40  ? 6.278   -19.901 2.702   1.00 37.16  ? 40  LEU A O   1 
ATOM 259   C CB  . LEU A 1 40  ? 8.204   -19.489 5.023   1.00 43.42  ? 40  LEU A CB  1 
ATOM 260   C CG  . LEU A 1 40  ? 8.396   -18.595 6.246   1.00 37.91  ? 40  LEU A CG  1 
ATOM 261   C CD1 . LEU A 1 40  ? 7.809   -19.235 7.496   1.00 49.67  ? 40  LEU A CD1 1 
ATOM 262   C CD2 . LEU A 1 40  ? 9.865   -18.251 6.451   1.00 53.22  ? 40  LEU A CD2 1 
ATOM 263   N N   . CYS A 1 41  ? 8.165   -19.948 1.492   1.00 41.47  ? 41  CYS A N   1 
ATOM 264   C CA  . CYS A 1 41  ? 7.583   -20.754 0.364   1.00 34.64  ? 41  CYS A CA  1 
ATOM 265   C C   . CYS A 1 41  ? 8.405   -22.028 0.197   1.00 38.41  ? 41  CYS A C   1 
ATOM 266   O O   . CYS A 1 41  ? 9.604   -21.896 0.009   1.00 41.76  ? 41  CYS A O   1 
ATOM 267   C CB  . CYS A 1 41  ? 7.576   -19.977 -0.943  1.00 32.38  ? 41  CYS A CB  1 
ATOM 268   S SG  . CYS A 1 41  ? 6.624   -20.737 -2.283  1.00 52.40  ? 41  CYS A SG  1 
ATOM 269   N N   . SER A 1 42  ? 7.807   -23.191 0.480   1.00 35.29  ? 42  SER A N   1 
ATOM 270   C CA  . SER A 1 42  ? 8.574   -24.467 0.481   1.00 38.89  ? 42  SER A CA  1 
ATOM 271   C C   . SER A 1 42  ? 8.566   -25.102 -0.907  1.00 37.26  ? 42  SER A C   1 
ATOM 272   O O   . SER A 1 42  ? 7.520   -25.659 -1.300  1.00 48.33  ? 42  SER A O   1 
ATOM 273   C CB  . SER A 1 42  ? 8.048   -25.415 1.524   1.00 35.99  ? 42  SER A CB  1 
ATOM 274   O OG  . SER A 1 42  ? 8.873   -26.566 1.621   1.00 44.73  ? 42  SER A OG  1 
ATOM 275   N N   . THR A 1 43  ? 9.697   -25.025 -1.608  1.00 39.33  ? 43  THR A N   1 
ATOM 276   C CA  . THR A 1 43  ? 9.797   -25.593 -2.974  1.00 42.94  ? 43  THR A CA  1 
ATOM 277   C C   . THR A 1 43  ? 11.129  -26.332 -3.101  1.00 51.81  ? 43  THR A C   1 
ATOM 278   O O   . THR A 1 43  ? 12.077  -25.951 -2.389  1.00 57.94  ? 43  THR A O   1 
ATOM 279   C CB  . THR A 1 43  ? 9.715   -24.467 -4.012  1.00 62.39  ? 43  THR A CB  1 
ATOM 280   O OG1 . THR A 1 43  ? 10.464  -23.375 -3.478  1.00 51.79  ? 43  THR A OG1 1 
ATOM 281   C CG2 . THR A 1 43  ? 8.300   -24.004 -4.275  1.00 57.97  ? 43  THR A CG2 1 
ATOM 282   N N   . PRO A 1 44  ? 11.256  -27.445 -3.877  1.00 55.19  ? 44  PRO A N   1 
ATOM 283   C CA  . PRO A 1 44  ? 12.562  -28.074 -4.139  1.00 51.57  ? 44  PRO A CA  1 
ATOM 284   C C   . PRO A 1 44  ? 13.468  -27.048 -4.830  1.00 50.87  ? 44  PRO A C   1 
ATOM 285   O O   . PRO A 1 44  ? 12.936  -26.234 -5.543  1.00 51.33  ? 44  PRO A O   1 
ATOM 286   C CB  . PRO A 1 44  ? 12.250  -29.281 -5.021  1.00 50.54  ? 44  PRO A CB  1 
ATOM 287   C CG  . PRO A 1 44  ? 10.846  -29.631 -4.645  1.00 61.57  ? 44  PRO A CG  1 
ATOM 288   C CD  . PRO A 1 44  ? 10.190  -28.278 -4.467  1.00 64.49  ? 44  PRO A CD  1 
ATOM 289   N N   . ILE A 1 45  ? 14.789  -27.113 -4.644  1.00 55.13  ? 45  ILE A N   1 
ATOM 290   C CA  . ILE A 1 45  ? 15.727  -26.055 -5.124  1.00 57.82  ? 45  ILE A CA  1 
ATOM 291   C C   . ILE A 1 45  ? 15.554  -25.863 -6.638  1.00 47.34  ? 45  ILE A C   1 
ATOM 292   O O   . ILE A 1 45  ? 15.557  -24.700 -7.081  1.00 46.88  ? 45  ILE A O   1 
ATOM 293   C CB  . ILE A 1 45  ? 17.180  -26.384 -4.716  1.00 54.85  ? 45  ILE A CB  1 
ATOM 294   C CG1 . ILE A 1 45  ? 18.178  -25.339 -5.224  1.00 60.34  ? 45  ILE A CG1 1 
ATOM 295   C CG2 . ILE A 1 45  ? 17.569  -27.795 -5.138  1.00 57.00  ? 45  ILE A CG2 1 
ATOM 296   C CD1 . ILE A 1 45  ? 18.008  -23.974 -4.598  1.00 39.20  ? 45  ILE A CD1 1 
ATOM 297   N N   . ASN A 1 46  ? 15.366  -26.950 -7.391  1.00 43.47  ? 46  ASN A N   1 
ATOM 298   C CA  . ASN A 1 46  ? 15.157  -26.843 -8.859  1.00 53.56  ? 46  ASN A CA  1 
ATOM 299   C C   . ASN A 1 46  ? 13.871  -26.055 -9.147  1.00 49.10  ? 46  ASN A C   1 
ATOM 300   O O   . ASN A 1 46  ? 13.892  -25.208 -10.056 1.00 53.58  ? 46  ASN A O   1 
ATOM 301   C CB  . ASN A 1 46  ? 15.108  -28.223 -9.518  1.00 58.73  ? 46  ASN A CB  1 
ATOM 302   C CG  . ASN A 1 46  ? 15.100  -28.166 -11.031 1.00 52.66  ? 46  ASN A CG  1 
ATOM 303   O OD1 . ASN A 1 46  ? 15.661  -27.248 -11.626 1.00 56.84  ? 46  ASN A OD1 1 
ATOM 304   N ND2 . ASN A 1 46  ? 14.477  -29.147 -11.662 1.00 53.68  ? 46  ASN A ND2 1 
ATOM 305   N N   . LEU A 1 47  ? 12.791  -26.336 -8.413  1.00 48.26  ? 47  LEU A N   1 
ATOM 306   C CA  . LEU A 1 47  ? 11.510  -25.599 -8.609  1.00 49.31  ? 47  LEU A CA  1 
ATOM 307   C C   . LEU A 1 47  ? 11.645  -24.129 -8.191  1.00 51.21  ? 47  LEU A C   1 
ATOM 308   O O   . LEU A 1 47  ? 11.073  -23.273 -8.882  1.00 48.84  ? 47  LEU A O   1 
ATOM 309   C CB  . LEU A 1 47  ? 10.376  -26.307 -7.861  1.00 47.62  ? 47  LEU A CB  1 
ATOM 310   C CG  . LEU A 1 47  ? 9.432   -27.119 -8.748  1.00 55.82  ? 47  LEU A CG  1 
ATOM 311   C CD1 . LEU A 1 47  ? 10.182  -28.205 -9.501  1.00 55.61  ? 47  LEU A CD1 1 
ATOM 312   C CD2 . LEU A 1 47  ? 8.309   -27.724 -7.926  1.00 67.77  ? 47  LEU A CD2 1 
ATOM 313   N N   . SER A 1 48  ? 12.350  -23.851 -7.090  1.00 53.47  ? 48  SER A N   1 
ATOM 314   C CA  . SER A 1 48  ? 12.475  -22.457 -6.587  1.00 53.90  ? 48  SER A CA  1 
ATOM 315   C C   . SER A 1 48  ? 13.402  -21.667 -7.512  1.00 57.22  ? 48  SER A C   1 
ATOM 316   O O   . SER A 1 48  ? 13.225  -20.441 -7.622  1.00 61.65  ? 48  SER A O   1 
ATOM 317   C CB  . SER A 1 48  ? 12.990  -22.446 -5.172  1.00 59.20  ? 48  SER A CB  1 
ATOM 318   O OG  . SER A 1 48  ? 14.314  -22.953 -5.111  1.00 64.00  ? 48  SER A OG  1 
ATOM 319   N N   . SER A 1 49  ? 14.350  -22.352 -8.153  1.00 57.14  ? 49  SER A N   1 
ATOM 320   C CA  . SER A 1 49  ? 15.339  -21.692 -9.049  1.00 49.72  ? 49  SER A CA  1 
ATOM 321   C C   . SER A 1 49  ? 14.666  -20.802 -10.084 1.00 55.24  ? 49  SER A C   1 
ATOM 322   O O   . SER A 1 49  ? 15.202  -19.725 -10.358 1.00 53.05  ? 49  SER A O   1 
ATOM 323   C CB  . SER A 1 49  ? 16.157  -22.723 -9.756  1.00 54.29  ? 49  SER A CB  1 
ATOM 324   O OG  . SER A 1 49  ? 15.448  -23.248 -10.865 1.00 63.21  ? 49  SER A OG  1 
ATOM 325   N N   . ILE A 1 50  ? 13.562  -21.261 -10.668 1.00 61.65  ? 50  ILE A N   1 
ATOM 326   C CA  . ILE A 1 50  ? 12.834  -20.497 -11.726 1.00 62.51  ? 50  ILE A CA  1 
ATOM 327   C C   . ILE A 1 50  ? 12.226  -19.224 -11.151 1.00 64.37  ? 50  ILE A C   1 
ATOM 328   O O   . ILE A 1 50  ? 12.152  -18.240 -11.889 1.00 73.13  ? 50  ILE A O   1 
ATOM 329   C CB  . ILE A 1 50  ? 11.739  -21.359 -12.363 1.00 66.65  ? 50  ILE A CB  1 
ATOM 330   C CG1 . ILE A 1 50  ? 11.308  -20.767 -13.706 1.00 70.85  ? 50  ILE A CG1 1 
ATOM 331   C CG2 . ILE A 1 50  ? 10.562  -21.544 -11.423 1.00 64.93  ? 50  ILE A CG2 1 
ATOM 332   C CD1 . ILE A 1 50  ? 12.468  -20.318 -14.570 1.00 58.53  ? 50  ILE A CD1 1 
ATOM 333   N N   . LYS A 1 51  ? 11.815  -19.252 -9.892  1.00 56.88  ? 51  LYS A N   1 
ATOM 334   C CA  . LYS A 1 51  ? 11.121  -18.093 -9.296  1.00 60.73  ? 51  LYS A CA  1 
ATOM 335   C C   . LYS A 1 51  ? 12.130  -17.073 -8.791  1.00 65.53  ? 51  LYS A C   1 
ATOM 336   O O   . LYS A 1 51  ? 11.696  -16.052 -8.266  1.00 69.01  ? 51  LYS A O   1 
ATOM 337   C CB  . LYS A 1 51  ? 10.214  -18.580 -8.169  1.00 52.65  ? 51  LYS A CB  1 
ATOM 338   C CG  . LYS A 1 51  ? 8.964   -19.282 -8.671  1.00 64.43  ? 51  LYS A CG  1 
ATOM 339   C CD  . LYS A 1 51  ? 8.351   -18.552 -9.850  1.00 69.04  ? 51  LYS A CD  1 
ATOM 340   C CE  . LYS A 1 51  ? 7.213   -19.298 -10.511 1.00 56.90  ? 51  LYS A CE  1 
ATOM 341   N NZ  . LYS A 1 51  ? 6.674   -18.543 -11.663 1.00 59.96  ? 51  LYS A NZ  1 
ATOM 342   N N   . ASP A 1 52  ? 13.423  -17.335 -8.931  1.00 69.50  ? 52  ASP A N   1 
ATOM 343   C CA  . ASP A 1 52  ? 14.393  -16.371 -8.342  1.00 75.43  ? 52  ASP A CA  1 
ATOM 344   C C   . ASP A 1 52  ? 14.608  -15.231 -9.345  1.00 77.67  ? 52  ASP A C   1 
ATOM 345   O O   . ASP A 1 52  ? 15.405  -15.390 -10.288 1.00 81.25  ? 52  ASP A O   1 
ATOM 346   C CB  . ASP A 1 52  ? 15.664  -17.061 -7.842  1.00 59.28  ? 52  ASP A CB  1 
ATOM 347   C CG  . ASP A 1 52  ? 16.452  -16.235 -6.849  1.00 76.64  ? 52  ASP A CG  1 
ATOM 348   O OD1 . ASP A 1 52  ? 16.832  -15.110 -7.209  1.00 88.14  ? 52  ASP A OD1 1 
ATOM 349   O OD2 . ASP A 1 52  ? 16.683  -16.731 -5.737  1.00 80.83  ? 52  ASP A OD2 1 
ATOM 350   N N   . LYS A 1 53  ? 13.883  -14.132 -9.168  1.00 68.42  ? 53  LYS A N   1 
ATOM 351   C CA  . LYS A 1 53  ? 13.979  -13.011 -10.130 1.00 67.81  ? 53  LYS A CA  1 
ATOM 352   C C   . LYS A 1 53  ? 13.464  -11.757 -9.419  1.00 76.00  ? 53  LYS A C   1 
ATOM 353   O O   . LYS A 1 53  ? 14.274  -10.848 -9.216  1.00 76.23  ? 53  LYS A O   1 
ATOM 354   C CB  . LYS A 1 53  ? 13.250  -13.411 -11.413 1.00 74.26  ? 53  LYS A CB  1 
ATOM 355   C CG  . LYS A 1 53  ? 11.860  -13.999 -11.201 1.00 71.14  ? 53  LYS A CG  1 
ATOM 356   C CD  . LYS A 1 53  ? 10.957  -13.874 -12.403 1.00 57.36  ? 53  LYS A CD  1 
ATOM 357   C CE  . LYS A 1 53  ? 9.523   -14.263 -12.112 1.00 61.23  ? 53  LYS A CE  1 
ATOM 358   N NZ  . LYS A 1 53  ? 9.374   -15.722 -11.910 1.00 60.35  ? 53  LYS A NZ  1 
ATOM 359   N N   . ASP A 1 54  ? 12.176  -11.699 -9.048  1.00 84.44  ? 54  ASP A N   1 
ATOM 360   C CA  . ASP A 1 54  ? 11.743  -10.540 -8.224  1.00 85.62  ? 54  ASP A CA  1 
ATOM 361   C C   . ASP A 1 54  ? 11.000  -11.079 -6.999  1.00 74.36  ? 54  ASP A C   1 
ATOM 362   O O   . ASP A 1 54  ? 9.763   -10.931 -6.948  1.00 69.42  ? 54  ASP A O   1 
ATOM 363   C CB  . ASP A 1 54  ? 10.872  -9.572  -9.028  1.00 82.46  ? 54  ASP A CB  1 
ATOM 364   C CG  . ASP A 1 54  ? 11.602  -8.895  -10.174 1.00 90.57  ? 54  ASP A CG  1 
ATOM 365   O OD1 . ASP A 1 54  ? 12.809  -9.164  -10.342 1.00 91.80  ? 54  ASP A OD1 1 
ATOM 366   O OD2 . ASP A 1 54  ? 10.958  -8.104  -10.891 1.00 95.59  ? 54  ASP A OD2 1 
ATOM 367   N N   . SER A 1 55  ? 11.728  -11.687 -6.056  1.00 63.63  ? 55  SER A N   1 
ATOM 368   C CA  . SER A 1 55  ? 11.070  -12.307 -4.876  1.00 70.95  ? 55  SER A CA  1 
ATOM 369   C C   . SER A 1 55  ? 11.754  -11.860 -3.580  1.00 72.97  ? 55  SER A C   1 
ATOM 370   O O   . SER A 1 55  ? 11.505  -12.498 -2.540  1.00 65.07  ? 55  SER A O   1 
ATOM 371   C CB  . SER A 1 55  ? 11.072  -13.809 -4.996  1.00 72.91  ? 55  SER A CB  1 
ATOM 372   O OG  . SER A 1 55  ? 12.398  -14.307 -5.101  1.00 74.52  ? 55  SER A OG  1 
ATOM 373   N N   . SER A 1 56  ? 12.577  -10.805 -3.635  1.00 67.89  ? 56  SER A N   1 
ATOM 374   C CA  . SER A 1 56  ? 13.189  -10.310 -2.408  1.00 65.73  ? 56  SER A CA  1 
ATOM 375   C C   . SER A 1 56  ? 12.179  -10.148 -1.279  1.00 58.11  ? 56  SER A C   1 
ATOM 376   O O   . SER A 1 56  ? 12.569  -10.158 -0.106  1.00 59.73  ? 56  SER A O   1 
ATOM 377   C CB  . SER A 1 56  ? 13.902  -8.986  -2.681  1.00 74.07  ? 56  SER A CB  1 
ATOM 378   O OG  . SER A 1 56  ? 14.970  -9.162  -3.596  1.00 88.87  ? 56  SER A OG  1 
ATOM 379   N N   . ALA A 1 57  ? 10.891  -10.015 -1.603  1.00 64.26  ? 57  ALA A N   1 
ATOM 380   C CA  . ALA A 1 57  ? 9.868   -9.881  -0.573  1.00 61.26  ? 57  ALA A CA  1 
ATOM 381   C C   . ALA A 1 57  ? 9.581   -11.210 0.113   1.00 57.31  ? 57  ALA A C   1 
ATOM 382   O O   . ALA A 1 57  ? 9.431   -11.259 1.337   1.00 64.21  ? 57  ALA A O   1 
ATOM 383   C CB  . ALA A 1 57  ? 8.586   -9.302  -1.173  1.00 50.25  ? 57  ALA A CB  1 
ATOM 384   N N   . SER A 1 58  ? 9.503   -12.292 -0.654  1.00 52.12  ? 58  SER A N   1 
ATOM 385   C CA  . SER A 1 58  ? 9.263   -13.615 -0.107  1.00 50.78  ? 58  SER A CA  1 
ATOM 386   C C   . SER A 1 58  ? 10.580  -14.286 0.270   1.00 49.64  ? 58  SER A C   1 
ATOM 387   O O   . SER A 1 58  ? 11.660  -13.884 -0.166  1.00 59.82  ? 58  SER A O   1 
ATOM 388   C CB  . SER A 1 58  ? 8.509   -14.487 -1.113  1.00 52.40  ? 58  SER A CB  1 
ATOM 389   O OG  . SER A 1 58  ? 7.308   -13.862 -1.544  1.00 51.10  ? 58  SER A OG  1 
ATOM 390   N N   . ILE A 1 59  ? 10.474  -15.324 1.093   1.00 39.66  ? 59  ILE A N   1 
ATOM 391   C CA  . ILE A 1 59  ? 11.614  -16.137 1.499   1.00 43.89  ? 59  ILE A CA  1 
ATOM 392   C C   . ILE A 1 59  ? 11.372  -17.557 1.005   1.00 34.84  ? 59  ILE A C   1 
ATOM 393   O O   . ILE A 1 59  ? 10.346  -18.167 1.330   1.00 40.18  ? 59  ILE A O   1 
ATOM 394   C CB  . ILE A 1 59  ? 11.826  -16.108 3.021   1.00 50.62  ? 59  ILE A CB  1 
ATOM 395   C CG1 . ILE A 1 59  ? 12.260  -14.710 3.477   1.00 56.00  ? 59  ILE A CG1 1 
ATOM 396   C CG2 . ILE A 1 59  ? 12.849  -17.154 3.441   1.00 55.76  ? 59  ILE A CG2 1 
ATOM 397   C CD1 . ILE A 1 59  ? 12.498  -14.595 4.968   1.00 58.06  ? 59  ILE A CD1 1 
ATOM 398   N N   . LYS A 1 60  ? 12.298  -18.004 0.175   1.00 33.66  ? 60  LYS A N   1 
ATOM 399   C CA  . LYS A 1 60  ? 12.139  -19.335 -0.427  1.00 38.49  ? 60  LYS A CA  1 
ATOM 400   C C   . LYS A 1 60  ? 12.896  -20.322 0.449   1.00 32.64  ? 60  LYS A C   1 
ATOM 401   O O   . LYS A 1 60  ? 13.978  -19.987 0.916   1.00 36.89  ? 60  LYS A O   1 
ATOM 402   C CB  . LYS A 1 60  ? 12.548  -19.245 -1.898  1.00 34.81  ? 60  LYS A CB  1 
ATOM 403   C CG  . LYS A 1 60  ? 11.864  -18.133 -2.675  1.00 39.70  ? 60  LYS A CG  1 
ATOM 404   C CD  . LYS A 1 60  ? 12.789  -17.477 -3.663  1.00 56.37  ? 60  LYS A CD  1 
ATOM 405   C CE  . LYS A 1 60  ? 13.368  -18.468 -4.646  1.00 62.95  ? 60  LYS A CE  1 
ATOM 406   N NZ  . LYS A 1 60  ? 12.303  -19.189 -5.380  1.00 67.45  ? 60  LYS A NZ  1 
ATOM 407   N N   . LEU A 1 61  ? 12.308  -21.483 0.665   1.00 37.47  ? 61  LEU A N   1 
ATOM 408   C CA  . LEU A 1 61  ? 12.883  -22.483 1.582   1.00 43.82  ? 61  LEU A CA  1 
ATOM 409   C C   . LEU A 1 61  ? 13.061  -23.779 0.801   1.00 41.28  ? 61  LEU A C   1 
ATOM 410   O O   . LEU A 1 61  ? 12.148  -24.159 0.090   1.00 38.54  ? 61  LEU A O   1 
ATOM 411   C CB  . LEU A 1 61  ? 11.887  -22.629 2.729   1.00 39.40  ? 61  LEU A CB  1 
ATOM 412   C CG  . LEU A 1 61  ? 12.007  -23.899 3.552   1.00 42.22  ? 61  LEU A CG  1 
ATOM 413   C CD1 . LEU A 1 61  ? 13.043  -23.729 4.647   1.00 51.03  ? 61  LEU A CD1 1 
ATOM 414   C CD2 . LEU A 1 61  ? 10.655  -24.225 4.139   1.00 53.46  ? 61  LEU A CD2 1 
ATOM 415   N N   . VAL A 1 62  ? 14.173  -24.475 0.950   1.00 37.39  ? 62  VAL A N   1 
ATOM 416   C CA  . VAL A 1 62  ? 14.344  -25.677 0.093   1.00 41.62  ? 62  VAL A CA  1 
ATOM 417   C C   . VAL A 1 62  ? 13.651  -26.892 0.715   1.00 48.58  ? 62  VAL A C   1 
ATOM 418   O O   . VAL A 1 62  ? 13.484  -26.901 1.937   1.00 51.06  ? 62  VAL A O   1 
ATOM 419   C CB  . VAL A 1 62  ? 15.836  -25.947 -0.161  1.00 55.32  ? 62  VAL A CB  1 
ATOM 420   C CG1 . VAL A 1 62  ? 16.299  -25.340 -1.475  1.00 47.64  ? 62  VAL A CG1 1 
ATOM 421   C CG2 . VAL A 1 62  ? 16.698  -25.453 0.988   1.00 69.89  ? 62  VAL A CG2 1 
ATOM 422   N N   . GLU A 1 63  ? 13.257  -27.867 -0.108  1.00 53.70  ? 63  GLU A N   1 
ATOM 423   C CA  . GLU A 1 63  ? 12.669  -29.136 0.391   1.00 44.96  ? 63  GLU A CA  1 
ATOM 424   C C   . GLU A 1 63  ? 13.268  -30.266 -0.442  1.00 56.83  ? 63  GLU A C   1 
ATOM 425   O O   . GLU A 1 63  ? 13.035  -30.264 -1.654  1.00 64.82  ? 63  GLU A O   1 
ATOM 426   C CB  . GLU A 1 63  ? 11.153  -29.137 0.250   1.00 42.71  ? 63  GLU A CB  1 
ATOM 427   C CG  . GLU A 1 63  ? 10.512  -30.376 0.834   1.00 51.56  ? 63  GLU A CG  1 
ATOM 428   C CD  . GLU A 1 63  ? 9.013   -30.245 1.015   1.00 60.74  ? 63  GLU A CD  1 
ATOM 429   O OE1 . GLU A 1 63  ? 8.456   -29.237 0.547   1.00 66.65  ? 63  GLU A OE1 1 
ATOM 430   O OE2 . GLU A 1 63  ? 8.412   -31.146 1.625   1.00 59.30  ? 63  GLU A OE2 1 
ATOM 431   N N   . LEU A 1 64  ? 14.012  -31.185 0.173   1.00 56.87  ? 64  LEU A N   1 
ATOM 432   C CA  . LEU A 1 64  ? 14.714  -32.229 -0.619  1.00 63.07  ? 64  LEU A CA  1 
ATOM 433   C C   . LEU A 1 64  ? 14.142  -33.614 -0.320  1.00 61.87  ? 64  LEU A C   1 
ATOM 434   O O   . LEU A 1 64  ? 14.125  -33.999 0.855   1.00 58.42  ? 64  LEU A O   1 
ATOM 435   C CB  . LEU A 1 64  ? 16.211  -32.133 -0.328  1.00 59.36  ? 64  LEU A CB  1 
ATOM 436   C CG  . LEU A 1 64  ? 16.792  -30.730 -0.502  1.00 63.72  ? 64  LEU A CG  1 
ATOM 437   C CD1 . LEU A 1 64  ? 17.563  -30.292 0.732   1.00 57.50  ? 64  LEU A CD1 1 
ATOM 438   C CD2 . LEU A 1 64  ? 17.664  -30.645 -1.742  1.00 62.50  ? 64  LEU A CD2 1 
ATOM 439   N N   . HIS A 1 65  ? 13.731  -34.335 -1.364  1.00 62.16  ? 65  HIS A N   1 
ATOM 440   C CA  . HIS A 1 65  ? 13.072  -35.657 -1.220  1.00 59.51  ? 65  HIS A CA  1 
ATOM 441   C C   . HIS A 1 65  ? 14.015  -36.756 -1.713  1.00 57.11  ? 65  HIS A C   1 
ATOM 442   O O   . HIS A 1 65  ? 13.677  -37.372 -2.730  1.00 46.27  ? 65  HIS A O   1 
ATOM 443   C CB  . HIS A 1 65  ? 11.762  -35.691 -2.009  1.00 51.81  ? 65  HIS A CB  1 
ATOM 444   C CG  . HIS A 1 65  ? 11.114  -34.367 -2.224  1.00 56.02  ? 65  HIS A CG  1 
ATOM 445   N ND1 . HIS A 1 65  ? 10.638  -33.599 -1.186  1.00 63.67  ? 65  HIS A ND1 1 
ATOM 446   C CD2 . HIS A 1 65  ? 10.835  -33.689 -3.354  1.00 54.02  ? 65  HIS A CD2 1 
ATOM 447   C CE1 . HIS A 1 65  ? 10.106  -32.497 -1.666  1.00 56.26  ? 65  HIS A CE1 1 
ATOM 448   N NE2 . HIS A 1 65  ? 10.216  -32.529 -2.990  1.00 60.77  ? 65  HIS A NE2 1 
ATOM 449   N N   . ARG A 1 91  ? 6.235   -42.715 -8.771  1.00 91.35  ? 91  ARG A N   1 
ATOM 450   C CA  . ARG A 1 91  ? 5.635   -42.296 -7.478  1.00 85.85  ? 91  ARG A CA  1 
ATOM 451   C C   . ARG A 1 91  ? 6.398   -41.089 -6.937  1.00 73.67  ? 91  ARG A C   1 
ATOM 452   O O   . ARG A 1 91  ? 7.538   -41.283 -6.497  1.00 75.42  ? 91  ARG A O   1 
ATOM 453   C CB  . ARG A 1 91  ? 5.706   -43.441 -6.466  1.00 81.77  ? 91  ARG A CB  1 
ATOM 454   C CG  . ARG A 1 91  ? 4.882   -44.663 -6.855  1.00 87.64  ? 91  ARG A CG  1 
ATOM 455   C CD  . ARG A 1 91  ? 3.535   -44.679 -6.159  1.00 90.28  ? 91  ARG A CD  1 
ATOM 456   N NE  . ARG A 1 91  ? 3.604   -44.049 -4.849  1.00 91.03  ? 91  ARG A NE  1 
ATOM 457   C CZ  . ARG A 1 91  ? 3.583   -44.705 -3.696  1.00 87.90  ? 91  ARG A CZ  1 
ATOM 458   N NH1 . ARG A 1 91  ? 3.489   -46.024 -3.688  1.00 82.56  ? 91  ARG A NH1 1 
ATOM 459   N NH2 . ARG A 1 91  ? 3.658   -44.041 -2.558  1.00 77.90  ? 91  ARG A NH2 1 
ATOM 460   N N   . ASN A 1 92  ? 5.793   -39.898 -6.988  1.00 77.63  ? 92  ASN A N   1 
ATOM 461   C CA  . ASN A 1 92  ? 6.454   -38.720 -6.381  1.00 74.34  ? 92  ASN A CA  1 
ATOM 462   C C   . ASN A 1 92  ? 6.801   -39.086 -4.942  1.00 76.01  ? 92  ASN A C   1 
ATOM 463   O O   . ASN A 1 92  ? 5.917   -39.557 -4.216  1.00 73.62  ? 92  ASN A O   1 
ATOM 464   C CB  . ASN A 1 92  ? 5.614   -37.447 -6.475  1.00 74.22  ? 92  ASN A CB  1 
ATOM 465   C CG  . ASN A 1 92  ? 4.280   -37.527 -5.762  1.00 84.10  ? 92  ASN A CG  1 
ATOM 466   O OD1 . ASN A 1 92  ? 3.857   -38.595 -5.332  1.00 89.60  ? 92  ASN A OD1 1 
ATOM 467   N ND2 . ASN A 1 92  ? 3.595   -36.399 -5.660  1.00 74.37  ? 92  ASN A ND2 1 
ATOM 468   N N   . ALA A 1 93  ? 8.063   -38.902 -4.570  1.00 68.46  ? 93  ALA A N   1 
ATOM 469   C CA  . ALA A 1 93  ? 8.471   -39.187 -3.185  1.00 65.24  ? 93  ALA A CA  1 
ATOM 470   C C   . ALA A 1 93  ? 7.857   -38.101 -2.315  1.00 69.48  ? 93  ALA A C   1 
ATOM 471   O O   . ALA A 1 93  ? 7.939   -38.199 -1.089  1.00 68.39  ? 93  ALA A O   1 
ATOM 472   C CB  . ALA A 1 93  ? 9.964   -39.203 -3.100  1.00 68.08  ? 93  ALA A CB  1 
ATOM 473   N N   . PHE A 1 94  ? 7.247   -37.098 -2.951  1.00 61.84  ? 94  PHE A N   1 
ATOM 474   C CA  . PHE A 1 94  ? 6.540   -36.056 -2.165  1.00 64.33  ? 94  PHE A CA  1 
ATOM 475   C C   . PHE A 1 94  ? 5.692   -36.765 -1.105  1.00 62.29  ? 94  PHE A C   1 
ATOM 476   O O   . PHE A 1 94  ? 5.570   -36.230 0.014   1.00 61.16  ? 94  PHE A O   1 
ATOM 477   C CB  . PHE A 1 94  ? 5.692   -35.172 -3.080  1.00 66.87  ? 94  PHE A CB  1 
ATOM 478   C CG  . PHE A 1 94  ? 5.417   -33.789 -2.545  1.00 65.66  ? 94  PHE A CG  1 
ATOM 479   C CD1 . PHE A 1 94  ? 5.996   -33.356 -1.363  1.00 63.39  ? 94  PHE A CD1 1 
ATOM 480   C CD2 . PHE A 1 94  ? 4.579   -32.917 -3.223  1.00 64.49  ? 94  PHE A CD2 1 
ATOM 481   C CE1 . PHE A 1 94  ? 5.743   -32.086 -0.871  1.00 63.79  ? 94  PHE A CE1 1 
ATOM 482   C CE2 . PHE A 1 94  ? 4.326   -31.647 -2.732  1.00 63.70  ? 94  PHE A CE2 1 
ATOM 483   C CZ  . PHE A 1 94  ? 4.907   -31.233 -1.556  1.00 64.40  ? 94  PHE A CZ  1 
ATOM 484   N N   . GLU A 1 95  ? 5.145   -37.938 -1.445  1.00 65.87  ? 95  GLU A N   1 
ATOM 485   C CA  . GLU A 1 95  ? 4.261   -38.636 -0.481  1.00 69.15  ? 95  GLU A CA  1 
ATOM 486   C C   . GLU A 1 95  ? 5.121   -39.315 0.581   1.00 69.28  ? 95  GLU A C   1 
ATOM 487   O O   . GLU A 1 95  ? 4.581   -40.138 1.334   1.00 71.28  ? 95  GLU A O   1 
ATOM 488   C CB  . GLU A 1 95  ? 3.370   -39.635 -1.214  1.00 73.27  ? 95  GLU A CB  1 
ATOM 489   C CG  . GLU A 1 95  ? 2.237   -38.975 -1.978  1.00 69.73  ? 95  GLU A CG  1 
ATOM 490   C CD  . GLU A 1 95  ? 1.150   -38.364 -1.111  1.00 75.44  ? 95  GLU A CD  1 
ATOM 491   O OE1 . GLU A 1 95  ? 1.247   -38.473 0.125   1.00 76.89  ? 95  GLU A OE1 1 
ATOM 492   O OE2 . GLU A 1 95  ? 0.205   -37.780 -1.675  1.00 81.01  ? 95  GLU A OE2 1 
ATOM 493   N N   . THR A 1 96  ? 6.408   -38.978 0.627   1.00 63.62  ? 96  THR A N   1 
ATOM 494   C CA  . THR A 1 96  ? 7.311   -39.582 1.631   1.00 62.54  ? 96  THR A CA  1 
ATOM 495   C C   . THR A 1 96  ? 8.012   -38.469 2.406   1.00 65.98  ? 96  THR A C   1 
ATOM 496   O O   . THR A 1 96  ? 8.544   -38.748 3.484   1.00 76.20  ? 96  THR A O   1 
ATOM 497   C CB  . THR A 1 96  ? 8.312   -40.507 0.940   1.00 70.50  ? 96  THR A CB  1 
ATOM 498   O OG1 . THR A 1 96  ? 9.258   -39.689 0.252   1.00 69.67  ? 96  THR A OG1 1 
ATOM 499   C CG2 . THR A 1 96  ? 7.654   -41.461 -0.032  1.00 61.51  ? 96  THR A CG2 1 
ATOM 500   N N   . ALA A 1 97  ? 7.991   -37.254 1.875   1.00 60.46  ? 97  ALA A N   1 
ATOM 501   C CA  . ALA A 1 97  ? 8.727   -36.144 2.513   1.00 55.04  ? 97  ALA A CA  1 
ATOM 502   C C   . ALA A 1 97  ? 7.851   -35.548 3.600   1.00 50.26  ? 97  ALA A C   1 
ATOM 503   O O   . ALA A 1 97  ? 8.035   -34.380 3.938   1.00 54.96  ? 97  ALA A O   1 
ATOM 504   C CB  . ALA A 1 97  ? 9.070   -35.114 1.483   1.00 50.15  ? 97  ALA A CB  1 
ATOM 505   N N   . GLY A 1 98  ? 6.927   -36.339 4.115   1.00 45.74  ? 98  GLY A N   1 
ATOM 506   C CA  . GLY A 1 98  ? 6.125   -35.828 5.230   1.00 47.94  ? 98  GLY A CA  1 
ATOM 507   C C   . GLY A 1 98  ? 7.046   -35.350 6.323   1.00 46.73  ? 98  GLY A C   1 
ATOM 508   O O   . GLY A 1 98  ? 7.122   -34.136 6.546   1.00 42.77  ? 98  GLY A O   1 
ATOM 509   N N   . PRO A 1 99  ? 7.753   -36.259 7.018   1.00 50.31  ? 99  PRO A N   1 
ATOM 510   C CA  . PRO A 1 99  ? 8.596   -35.834 8.149   1.00 50.34  ? 99  PRO A CA  1 
ATOM 511   C C   . PRO A 1 99  ? 9.612   -34.766 7.788   1.00 47.59  ? 99  PRO A C   1 
ATOM 512   O O   . PRO A 1 99  ? 10.022  -33.993 8.665   1.00 48.97  ? 99  PRO A O   1 
ATOM 513   C CB  . PRO A 1 99  ? 9.278   -37.139 8.592   1.00 48.69  ? 99  PRO A CB  1 
ATOM 514   C CG  . PRO A 1 99  ? 9.099   -38.089 7.448   1.00 53.37  ? 99  PRO A CG  1 
ATOM 515   C CD  . PRO A 1 99  ? 7.805   -37.715 6.810   1.00 49.65  ? 99  PRO A CD  1 
ATOM 516   N N   . THR A 1 100 ? 10.022  -34.675 6.523   1.00 48.97  ? 100 THR A N   1 
ATOM 517   C CA  . THR A 1 100 ? 10.909  -33.588 6.118   1.00 47.76  ? 100 THR A CA  1 
ATOM 518   C C   . THR A 1 100 ? 10.205  -32.242 6.245   1.00 46.66  ? 100 THR A C   1 
ATOM 519   O O   . THR A 1 100 ? 10.758  -31.284 6.801   1.00 42.36  ? 100 THR A O   1 
ATOM 520   C CB  . THR A 1 100 ? 11.392  -33.811 4.687   1.00 47.57  ? 100 THR A CB  1 
ATOM 521   O OG1 . THR A 1 100 ? 11.832  -35.166 4.536   1.00 50.66  ? 100 THR A OG1 1 
ATOM 522   C CG2 . THR A 1 100 ? 12.547  -32.874 4.372   1.00 46.83  ? 100 THR A CG2 1 
ATOM 523   N N   . PHE A 1 101 ? 8.973   -32.155 5.744   1.00 39.90  ? 101 PHE A N   1 
ATOM 524   C CA  . PHE A 1 101 ? 8.202   -30.930 5.908   1.00 40.90  ? 101 PHE A CA  1 
ATOM 525   C C   . PHE A 1 101 ? 7.840   -30.696 7.369   1.00 43.74  ? 101 PHE A C   1 
ATOM 526   O O   . PHE A 1 101 ? 7.714   -29.543 7.798   1.00 45.08  ? 101 PHE A O   1 
ATOM 527   C CB  . PHE A 1 101 ? 6.946   -30.982 5.041   1.00 39.83  ? 101 PHE A CB  1 
ATOM 528   C CG  . PHE A 1 101 ? 6.190   -29.687 4.991   1.00 46.26  ? 101 PHE A CG  1 
ATOM 529   C CD1 . PHE A 1 101 ? 6.790   -28.539 4.503   1.00 39.59  ? 101 PHE A CD1 1 
ATOM 530   C CD2 . PHE A 1 101 ? 4.876   -29.622 5.423   1.00 47.43  ? 101 PHE A CD2 1 
ATOM 531   C CE1 . PHE A 1 101 ? 6.096   -27.347 4.453   1.00 34.32  ? 101 PHE A CE1 1 
ATOM 532   C CE2 . PHE A 1 101 ? 4.177   -28.435 5.372   1.00 48.29  ? 101 PHE A CE2 1 
ATOM 533   C CZ  . PHE A 1 101 ? 4.787   -27.295 4.887   1.00 39.62  ? 101 PHE A CZ  1 
ATOM 534   N N   . SER A 1 102 ? 7.676   -31.770 8.143   1.00 42.71  ? 102 SER A N   1 
ATOM 535   C CA  . SER A 1 102 ? 7.470   -31.617 9.579   1.00 41.38  ? 102 SER A CA  1 
ATOM 536   C C   . SER A 1 102 ? 8.673   -30.944 10.229  1.00 44.98  ? 102 SER A C   1 
ATOM 537   O O   . SER A 1 102 ? 8.514   -30.053 11.067  1.00 48.19  ? 102 SER A O   1 
ATOM 538   C CB  . SER A 1 102 ? 7.201   -32.978 10.222  1.00 48.08  ? 102 SER A CB  1 
ATOM 539   O OG  . SER A 1 102 ? 6.997   -32.848 11.617  1.00 47.03  ? 102 SER A OG  1 
ATOM 540   N N   . GLU A 1 103 ? 9.884   -31.355 9.844   1.00 43.51  ? 103 GLU A N   1 
ATOM 541   C CA  . GLU A 1 103 ? 11.092  -30.706 10.341  1.00 41.74  ? 103 GLU A CA  1 
ATOM 542   C C   . GLU A 1 103 ? 11.163  -29.249 9.896   1.00 43.73  ? 103 GLU A C   1 
ATOM 543   O O   . GLU A 1 103 ? 11.560  -28.367 10.671  1.00 42.35  ? 103 GLU A O   1 
ATOM 544   C CB  . GLU A 1 103 ? 12.326  -31.472 9.863   1.00 43.77  ? 103 GLU A CB  1 
ATOM 545   C CG  . GLU A 1 103 ? 13.641  -30.969 10.428  1.00 41.26  ? 103 GLU A CG  1 
ATOM 546   C CD  . GLU A 1 103 ? 13.864  -31.403 11.865  1.00 66.28  ? 103 GLU A CD  1 
ATOM 547   O OE1 . GLU A 1 103 ? 13.178  -32.346 12.316  1.00 59.00  ? 103 GLU A OE1 1 
ATOM 548   O OE2 . GLU A 1 103 ? 14.725  -30.804 12.540  1.00 73.66  ? 103 GLU A OE2 1 
ATOM 549   N N   . ILE A 1 104 ? 10.787  -28.978 8.643   1.00 39.81  ? 104 ILE A N   1 
ATOM 550   C CA  . ILE A 1 104 ? 10.810  -27.602 8.147   1.00 42.89  ? 104 ILE A CA  1 
ATOM 551   C C   . ILE A 1 104 ? 9.870   -26.722 8.965   1.00 42.70  ? 104 ILE A C   1 
ATOM 552   O O   . ILE A 1 104 ? 10.226  -25.608 9.366   1.00 44.56  ? 104 ILE A O   1 
ATOM 553   C CB  . ILE A 1 104 ? 10.469  -27.564 6.646   1.00 49.60  ? 104 ILE A CB  1 
ATOM 554   C CG1 . ILE A 1 104 ? 11.686  -27.980 5.817   1.00 45.25  ? 104 ILE A CG1 1 
ATOM 555   C CG2 . ILE A 1 104 ? 9.991   -26.180 6.236   1.00 53.69  ? 104 ILE A CG2 1 
ATOM 556   C CD1 . ILE A 1 104 ? 11.526  -27.771 4.330   1.00 50.12  ? 104 ILE A CD1 1 
ATOM 557   N N   . LEU A 1 105 ? 8.656   -27.213 9.231   1.00 42.91  ? 105 LEU A N   1 
ATOM 558   C CA  . LEU A 1 105 ? 7.717   -26.449 10.048  1.00 46.80  ? 105 LEU A CA  1 
ATOM 559   C C   . LEU A 1 105 ? 8.189   -26.344 11.492  1.00 42.18  ? 105 LEU A C   1 
ATOM 560   O O   . LEU A 1 105 ? 7.935   -25.330 12.154  1.00 42.91  ? 105 LEU A O   1 
ATOM 561   C CB  . LEU A 1 105 ? 6.326   -27.080 9.998   1.00 41.92  ? 105 LEU A CB  1 
ATOM 562   C CG  . LEU A 1 105 ? 5.610   -27.141 8.647   1.00 47.88  ? 105 LEU A CG  1 
ATOM 563   C CD1 . LEU A 1 105 ? 4.224   -27.743 8.825   1.00 49.99  ? 105 LEU A CD1 1 
ATOM 564   C CD2 . LEU A 1 105 ? 5.522   -25.764 8.007   1.00 39.56  ? 105 LEU A CD2 1 
ATOM 565   N N   . LYS A 1 106 ? 8.867   -27.376 11.995  1.00 42.93  ? 106 LYS A N   1 
ATOM 566   C CA  . LYS A 1 106 ? 9.410   -27.333 13.347  1.00 46.33  ? 106 LYS A CA  1 
ATOM 567   C C   . LYS A 1 106 ? 10.455  -26.235 13.481  1.00 47.16  ? 106 LYS A C   1 
ATOM 568   O O   . LYS A 1 106 ? 10.552  -25.582 14.525  1.00 53.76  ? 106 LYS A O   1 
ATOM 569   C CB  . LYS A 1 106 ? 10.006  -28.696 13.698  1.00 52.48  ? 106 LYS A CB  1 
ATOM 570   C CG  . LYS A 1 106 ? 10.234  -28.940 15.171  1.00 61.82  ? 106 LYS A CG  1 
ATOM 571   C CD  . LYS A 1 106 ? 10.770  -30.345 15.395  1.00 65.28  ? 106 LYS A CD  1 
ATOM 572   C CE  . LYS A 1 106 ? 12.204  -30.483 14.904  1.00 60.52  ? 106 LYS A CE  1 
ATOM 573   N NZ  . LYS A 1 106 ? 13.162  -29.694 15.730  1.00 62.24  ? 106 LYS A NZ  1 
ATOM 574   N N   . THR A 1 107 ? 11.179  -25.978 12.389  1.00 45.27  ? 107 THR A N   1 
ATOM 575   C CA  . THR A 1 107 ? 12.175  -24.875 12.390  1.00 45.22  ? 107 THR A CA  1 
ATOM 576   C C   . THR A 1 107 ? 11.464  -23.552 12.084  1.00 44.49  ? 107 THR A C   1 
ATOM 577   O O   . THR A 1 107 ? 11.620  -22.606 12.878  1.00 45.74  ? 107 THR A O   1 
ATOM 578   C CB  . THR A 1 107 ? 13.295  -25.147 11.382  1.00 57.14  ? 107 THR A CB  1 
ATOM 579   O OG1 . THR A 1 107 ? 13.895  -26.400 11.711  1.00 59.75  ? 107 THR A OG1 1 
ATOM 580   C CG2 . THR A 1 107 ? 14.348  -24.061 11.364  1.00 54.43  ? 107 THR A CG2 1 
ATOM 581   N N   . LEU A 1 108 ? 10.712  -23.495 10.978  1.00 51.97  ? 108 LEU A N   1 
ATOM 582   C CA  . LEU A 1 108 ? 10.038  -22.233 10.566  1.00 46.15  ? 108 LEU A CA  1 
ATOM 583   C C   . LEU A 1 108 ? 8.922   -21.877 11.553  1.00 49.54  ? 108 LEU A C   1 
ATOM 584   O O   . LEU A 1 108 ? 8.876   -20.710 11.986  1.00 43.27  ? 108 LEU A O   1 
ATOM 585   C CB  . LEU A 1 108 ? 9.473   -22.412 9.154   1.00 50.63  ? 108 LEU A CB  1 
ATOM 586   C CG  . LEU A 1 108 ? 10.508  -22.664 8.058   1.00 57.25  ? 108 LEU A CG  1 
ATOM 587   C CD1 . LEU A 1 108 ? 9.942   -22.309 6.694   1.00 55.17  ? 108 LEU A CD1 1 
ATOM 588   C CD2 . LEU A 1 108 ? 11.782  -21.882 8.327   1.00 54.14  ? 108 LEU A CD2 1 
ATOM 589   N N   . ASN A 1 109 ? 8.059   -22.842 11.883  1.00 53.04  ? 109 ASN A N   1 
ATOM 590   C CA  . ASN A 1 109 ? 6.910   -22.575 12.795  1.00 53.73  ? 109 ASN A CA  1 
ATOM 591   C C   . ASN A 1 109 ? 6.114   -21.376 12.261  1.00 46.38  ? 109 ASN A C   1 
ATOM 592   O O   . ASN A 1 109 ? 6.097   -20.328 12.938  1.00 32.26  ? 109 ASN A O   1 
ATOM 593   C CB  . ASN A 1 109 ? 7.372   -22.363 14.240  1.00 47.17  ? 109 ASN A CB  1 
ATOM 594   C CG  . ASN A 1 109 ? 6.241   -22.465 15.241  1.00 67.82  ? 109 ASN A CG  1 
ATOM 595   O OD1 . ASN A 1 109 ? 5.282   -21.701 15.186  1.00 71.02  ? 109 ASN A OD1 1 
ATOM 596   N ND2 . ASN A 1 109 ? 6.348   -23.408 16.163  1.00 78.97  ? 109 ASN A ND2 1 
ATOM 597   N N   . PRO A 1 110 ? 5.461   -21.480 11.082  1.00 47.67  ? 110 PRO A N   1 
ATOM 598   C CA  . PRO A 1 110 ? 4.652   -20.384 10.537  1.00 46.34  ? 110 PRO A CA  1 
ATOM 599   C C   . PRO A 1 110 ? 3.328   -20.224 11.297  1.00 45.18  ? 110 PRO A C   1 
ATOM 600   O O   . PRO A 1 110 ? 2.873   -21.190 11.883  1.00 43.29  ? 110 PRO A O   1 
ATOM 601   C CB  . PRO A 1 110 ? 4.371   -20.839 9.099   1.00 38.60  ? 110 PRO A CB  1 
ATOM 602   C CG  . PRO A 1 110 ? 4.377   -22.347 9.194   1.00 42.56  ? 110 PRO A CG  1 
ATOM 603   C CD  . PRO A 1 110 ? 5.453   -22.659 10.212  1.00 42.31  ? 110 PRO A CD  1 
ATOM 604   N N   . ASP A 1 111 ? 2.746   -19.022 11.262  1.00 50.70  ? 111 ASP A N   1 
ATOM 605   C CA  . ASP A 1 111 ? 1.453   -18.767 11.955  1.00 44.45  ? 111 ASP A CA  1 
ATOM 606   C C   . ASP A 1 111 ? 0.318   -19.401 11.148  1.00 48.60  ? 111 ASP A C   1 
ATOM 607   O O   . ASP A 1 111 ? -0.823  -19.408 11.652  1.00 52.25  ? 111 ASP A O   1 
ATOM 608   C CB  . ASP A 1 111 ? 1.212   -17.268 12.146  1.00 51.36  ? 111 ASP A CB  1 
ATOM 609   C CG  . ASP A 1 111 ? 2.357   -16.550 12.843  1.00 69.23  ? 111 ASP A CG  1 
ATOM 610   O OD1 . ASP A 1 111 ? 3.333   -17.230 13.219  1.00 71.15  ? 111 ASP A OD1 1 
ATOM 611   O OD2 . ASP A 1 111 ? 2.267   -15.315 12.995  1.00 65.67  ? 111 ASP A OD2 1 
ATOM 612   N N   . LEU A 1 112 ? 0.618   -19.912 9.952   1.00 47.00  ? 112 LEU A N   1 
ATOM 613   C CA  . LEU A 1 112 ? -0.414  -20.478 9.094   1.00 48.09  ? 112 LEU A CA  1 
ATOM 614   C C   . LEU A 1 112 ? 0.239   -21.161 7.900   1.00 36.44  ? 112 LEU A C   1 
ATOM 615   O O   . LEU A 1 112 ? 1.302   -20.744 7.436   1.00 39.03  ? 112 LEU A O   1 
ATOM 616   C CB  . LEU A 1 112 ? -1.396  -19.396 8.629   1.00 48.59  ? 112 LEU A CB  1 
ATOM 617   C CG  . LEU A 1 112 ? -2.684  -19.844 7.939   1.00 43.74  ? 112 LEU A CG  1 
ATOM 618   C CD1 . LEU A 1 112 ? -3.827  -18.940 8.355   1.00 45.48  ? 112 LEU A CD1 1 
ATOM 619   C CD2 . LEU A 1 112 ? -2.520  -19.832 6.428   1.00 39.17  ? 112 LEU A CD2 1 
ATOM 620   N N   . LEU A 1 113 ? -0.414  -22.211 7.407   1.00 31.53  ? 113 LEU A N   1 
ATOM 621   C CA  . LEU A 1 113 ? 0.060   -22.964 6.257   1.00 32.67  ? 113 LEU A CA  1 
ATOM 622   C C   . LEU A 1 113 ? -0.966  -22.897 5.133   1.00 35.36  ? 113 LEU A C   1 
ATOM 623   O O   . LEU A 1 113 ? -2.171  -23.037 5.370   1.00 33.74  ? 113 LEU A O   1 
ATOM 624   C CB  . LEU A 1 113 ? 0.330   -24.427 6.625   1.00 33.96  ? 113 LEU A CB  1 
ATOM 625   C CG  . LEU A 1 113 ? 0.669   -25.361 5.462   1.00 30.96  ? 113 LEU A CG  1 
ATOM 626   C CD1 . LEU A 1 113 ? 1.961   -24.932 4.785   1.00 33.86  ? 113 LEU A CD1 1 
ATOM 627   C CD2 . LEU A 1 113 ? 0.759   -26.805 5.926   1.00 22.02  ? 113 LEU A CD2 1 
ATOM 628   N N   . ILE A 1 114 ? -0.485  -22.682 3.910   1.00 31.54  ? 114 ILE A N   1 
ATOM 629   C CA  . ILE A 1 114 ? -1.322  -22.672 2.713   1.00 32.12  ? 114 ILE A CA  1 
ATOM 630   C C   . ILE A 1 114 ? -0.843  -23.805 1.812   1.00 37.47  ? 114 ILE A C   1 
ATOM 631   O O   . ILE A 1 114 ? 0.230   -23.712 1.202   1.00 40.70  ? 114 ILE A O   1 
ATOM 632   C CB  . ILE A 1 114 ? -1.274  -21.325 1.983   1.00 35.18  ? 114 ILE A CB  1 
ATOM 633   C CG1 . ILE A 1 114 ? -1.824  -20.216 2.878   1.00 36.99  ? 114 ILE A CG1 1 
ATOM 634   C CG2 . ILE A 1 114 ? -2.055  -21.401 0.684   1.00 33.44  ? 114 ILE A CG2 1 
ATOM 635   C CD1 . ILE A 1 114 ? -1.842  -18.847 2.231   1.00 30.11  ? 114 ILE A CD1 1 
ATOM 636   N N   . TYR A 1 115 ? -1.644  -24.860 1.717   1.00 34.88  ? 115 TYR A N   1 
ATOM 637   C CA  . TYR A 1 115 ? -1.268  -26.090 1.035   1.00 40.12  ? 115 TYR A CA  1 
ATOM 638   C C   . TYR A 1 115 ? -2.040  -26.244 -0.270  1.00 40.11  ? 115 TYR A C   1 
ATOM 639   O O   . TYR A 1 115 ? -3.007  -25.528 -0.545  1.00 35.98  ? 115 TYR A O   1 
ATOM 640   C CB  . TYR A 1 115 ? -1.500  -27.300 1.948   1.00 36.64  ? 115 TYR A CB  1 
ATOM 641   C CG  . TYR A 1 115 ? -2.941  -27.518 2.354   1.00 43.07  ? 115 TYR A CG  1 
ATOM 642   C CD1 . TYR A 1 115 ? -3.515  -26.794 3.396   1.00 37.39  ? 115 TYR A CD1 1 
ATOM 643   C CD2 . TYR A 1 115 ? -3.723  -28.467 1.710   1.00 43.47  ? 115 TYR A CD2 1 
ATOM 644   C CE1 . TYR A 1 115 ? -4.833  -26.999 3.769   1.00 35.46  ? 115 TYR A CE1 1 
ATOM 645   C CE2 . TYR A 1 115 ? -5.038  -28.680 2.076   1.00 45.46  ? 115 TYR A CE2 1 
ATOM 646   C CZ  . TYR A 1 115 ? -5.587  -27.946 3.106   1.00 40.36  ? 115 TYR A CZ  1 
ATOM 647   O OH  . TYR A 1 115 ? -6.900  -28.157 3.467   1.00 35.10  ? 115 TYR A OH  1 
ATOM 648   N N   . ASP A 1 116 ? -1.592  -27.200 -1.082  1.00 43.97  ? 116 ASP A N   1 
ATOM 649   C CA  . ASP A 1 116 ? -2.193  -27.467 -2.380  1.00 42.04  ? 116 ASP A CA  1 
ATOM 650   C C   . ASP A 1 116 ? -3.084  -28.705 -2.305  1.00 49.18  ? 116 ASP A C   1 
ATOM 651   O O   . ASP A 1 116 ? -3.594  -29.050 -1.235  1.00 52.69  ? 116 ASP A O   1 
ATOM 652   C CB  . ASP A 1 116 ? -1.094  -27.626 -3.440  1.00 43.54  ? 116 ASP A CB  1 
ATOM 653   C CG  . ASP A 1 116 ? -1.517  -27.127 -4.806  1.00 50.46  ? 116 ASP A CG  1 
ATOM 654   O OD1 . ASP A 1 116 ? -2.731  -27.124 -5.086  1.00 44.67  ? 116 ASP A OD1 1 
ATOM 655   O OD2 . ASP A 1 116 ? -0.635  -26.737 -5.599  1.00 57.41  ? 116 ASP A OD2 1 
ATOM 656   N N   . PHE A 1 117 ? -3.269  -29.394 -3.430  1.00 47.71  ? 117 PHE A N   1 
ATOM 657   C CA  . PHE A 1 117 ? -4.285  -30.438 -3.504  1.00 53.53  ? 117 PHE A CA  1 
ATOM 658   C C   . PHE A 1 117 ? -3.744  -31.835 -3.245  1.00 54.87  ? 117 PHE A C   1 
ATOM 659   O O   . PHE A 1 117 ? -4.474  -32.687 -2.720  1.00 55.15  ? 117 PHE A O   1 
ATOM 660   C CB  . PHE A 1 117 ? -4.966  -30.418 -4.874  1.00 44.02  ? 117 PHE A CB  1 
ATOM 661   C CG  . PHE A 1 117 ? -4.060  -30.799 -6.014  1.00 47.10  ? 117 PHE A CG  1 
ATOM 662   C CD1 . PHE A 1 117 ? -3.226  -29.859 -6.594  1.00 52.11  ? 117 PHE A CD1 1 
ATOM 663   C CD2 . PHE A 1 117 ? -4.055  -32.092 -6.514  1.00 42.11  ? 117 PHE A CD2 1 
ATOM 664   C CE1 . PHE A 1 117 ? -2.398  -30.201 -7.645  1.00 44.41  ? 117 PHE A CE1 1 
ATOM 665   C CE2 . PHE A 1 117 ? -3.227  -32.441 -7.564  1.00 51.87  ? 117 PHE A CE2 1 
ATOM 666   C CZ  . PHE A 1 117 ? -2.398  -31.493 -8.131  1.00 44.53  ? 117 PHE A CZ  1 
ATOM 667   N N   . ASN A 1 118 ? -2.499  -32.096 -3.607  1.00 55.84  ? 118 ASN A N   1 
ATOM 668   C CA  . ASN A 1 118 ? -1.982  -33.458 -3.578  1.00 66.07  ? 118 ASN A CA  1 
ATOM 669   C C   . ASN A 1 118 ? -1.015  -33.776 -2.439  1.00 68.24  ? 118 ASN A C   1 
ATOM 670   O O   . ASN A 1 118 ? -0.846  -34.962 -2.130  1.00 83.35  ? 118 ASN A O   1 
ATOM 671   C CB  . ASN A 1 118 ? -1.287  -33.796 -4.898  1.00 65.55  ? 118 ASN A CB  1 
ATOM 672   C CG  . ASN A 1 118 ? -1.298  -35.284 -5.178  1.00 69.63  ? 118 ASN A CG  1 
ATOM 673   O OD1 . ASN A 1 118 ? -2.247  -35.977 -4.811  1.00 72.34  ? 118 ASN A OD1 1 
ATOM 674   N ND2 . ASN A 1 118 ? -0.246  -35.786 -5.815  1.00 73.11  ? 118 ASN A ND2 1 
ATOM 675   N N   . PRO A 1 119 ? -0.325  -32.797 -1.830  1.00 55.26  ? 119 PRO A N   1 
ATOM 676   C CA  . PRO A 1 119 ? 0.521   -33.131 -0.668  1.00 56.31  ? 119 PRO A CA  1 
ATOM 677   C C   . PRO A 1 119 ? -0.152  -34.027 0.371   1.00 58.21  ? 119 PRO A C   1 
ATOM 678   O O   . PRO A 1 119 ? 0.549   -34.781 1.060   1.00 71.62  ? 119 PRO A O   1 
ATOM 679   C CB  . PRO A 1 119 ? 0.888   -31.747 -0.115  1.00 59.14  ? 119 PRO A CB  1 
ATOM 680   C CG  . PRO A 1 119 ? 1.041   -30.915 -1.360  1.00 56.58  ? 119 PRO A CG  1 
ATOM 681   C CD  . PRO A 1 119 ? -0.003  -31.451 -2.343  1.00 49.54  ? 119 PRO A CD  1 
ATOM 682   N N   . SER A 1 120 ? -1.482  -34.026 0.475   1.00 49.55  ? 120 SER A N   1 
ATOM 683   C CA  . SER A 1 120 ? -2.211  -34.982 1.365   1.00 57.01  ? 120 SER A CA  1 
ATOM 684   C C   . SER A 1 120 ? -1.840  -34.869 2.850   1.00 55.62  ? 120 SER A C   1 
ATOM 685   O O   . SER A 1 120 ? -2.742  -34.648 3.667   1.00 45.90  ? 120 SER A O   1 
ATOM 686   C CB  . SER A 1 120 ? -2.009  -36.389 0.899   1.00 53.16  ? 120 SER A CB  1 
ATOM 687   O OG  . SER A 1 120 ? -2.428  -37.316 1.885   1.00 49.99  ? 120 SER A OG  1 
ATOM 688   N N   . TRP A 1 121 ? -0.574  -35.082 3.189   1.00 47.91  ? 121 TRP A N   1 
ATOM 689   C CA  . TRP A 1 121 ? -0.143  -35.073 4.607   1.00 52.78  ? 121 TRP A CA  1 
ATOM 690   C C   . TRP A 1 121 ? 0.000   -33.639 5.104   1.00 57.22  ? 121 TRP A C   1 
ATOM 691   O O   . TRP A 1 121 ? 0.100   -33.440 6.319   1.00 56.18  ? 121 TRP A O   1 
ATOM 692   C CB  . TRP A 1 121 ? 1.163   -35.853 4.754   1.00 53.99  ? 121 TRP A CB  1 
ATOM 693   C CG  . TRP A 1 121 ? 2.218   -35.566 3.730   1.00 53.22  ? 121 TRP A CG  1 
ATOM 694   C CD1 . TRP A 1 121 ? 2.676   -36.421 2.771   1.00 51.52  ? 121 TRP A CD1 1 
ATOM 695   C CD2 . TRP A 1 121 ? 2.997   -34.366 3.598   1.00 48.42  ? 121 TRP A CD2 1 
ATOM 696   N NE1 . TRP A 1 121 ? 3.660   -35.825 2.031   1.00 46.94  ? 121 TRP A NE1 1 
ATOM 697   C CE2 . TRP A 1 121 ? 3.881   -34.564 2.516   1.00 53.69  ? 121 TRP A CE2 1 
ATOM 698   C CE3 . TRP A 1 121 ? 3.028   -33.142 4.272   1.00 46.89  ? 121 TRP A CE3 1 
ATOM 699   C CZ2 . TRP A 1 121 ? 4.778   -33.585 2.098   1.00 53.16  ? 121 TRP A CZ2 1 
ATOM 700   C CZ3 . TRP A 1 121 ? 3.912   -32.174 3.856   1.00 53.78  ? 121 TRP A CZ3 1 
ATOM 701   C CH2 . TRP A 1 121 ? 4.774   -32.394 2.785   1.00 49.14  ? 121 TRP A CH2 1 
ATOM 702   N N   . ALA A 1 122 ? -0.006  -32.681 4.189   1.00 57.01  ? 122 ALA A N   1 
ATOM 703   C CA  . ALA A 1 122 ? 0.198   -31.273 4.573   1.00 50.20  ? 122 ALA A CA  1 
ATOM 704   C C   . ALA A 1 122 ? -0.785  -30.901 5.674   1.00 41.07  ? 122 ALA A C   1 
ATOM 705   O O   . ALA A 1 122 ? -0.337  -30.444 6.726   1.00 44.77  ? 122 ALA A O   1 
ATOM 706   C CB  . ALA A 1 122 ? 0.013   -30.407 3.361   1.00 46.40  ? 122 ALA A CB  1 
ATOM 707   N N   . PRO A 1 123 ? -2.101  -31.080 5.481   1.00 42.42  ? 123 PRO A N   1 
ATOM 708   C CA  . PRO A 1 123 ? -3.056  -30.652 6.491   1.00 50.44  ? 123 PRO A CA  1 
ATOM 709   C C   . PRO A 1 123 ? -2.832  -31.401 7.814   1.00 45.99  ? 123 PRO A C   1 
ATOM 710   O O   . PRO A 1 123 ? -2.984  -30.801 8.856   1.00 43.27  ? 123 PRO A O   1 
ATOM 711   C CB  . PRO A 1 123 ? -4.407  -30.950 5.820   1.00 43.57  ? 123 PRO A CB  1 
ATOM 712   C CG  . PRO A 1 123 ? -4.109  -32.009 4.796   1.00 52.43  ? 123 PRO A CG  1 
ATOM 713   C CD  . PRO A 1 123 ? -2.729  -31.657 4.296   1.00 47.70  ? 123 PRO A CD  1 
ATOM 714   N N   . GLU A 1 124 ? -2.442  -32.669 7.741   1.00 44.84  ? 124 GLU A N   1 
ATOM 715   C CA  . GLU A 1 124 ? -2.264  -33.501 8.955   1.00 49.27  ? 124 GLU A CA  1 
ATOM 716   C C   . GLU A 1 124 ? -1.013  -33.081 9.733   1.00 50.03  ? 124 GLU A C   1 
ATOM 717   O O   . GLU A 1 124 ? -1.112  -32.958 10.960  1.00 50.29  ? 124 GLU A O   1 
ATOM 718   C CB  . GLU A 1 124 ? -2.166  -34.959 8.516   1.00 45.90  ? 124 GLU A CB  1 
ATOM 719   C CG  . GLU A 1 124 ? -3.053  -35.293 7.330   1.00 58.14  ? 124 GLU A CG  1 
ATOM 720   C CD  . GLU A 1 124 ? -2.808  -36.655 6.703   1.00 66.75  ? 124 GLU A CD  1 
ATOM 721   O OE1 . GLU A 1 124 ? -1.947  -37.394 7.213   1.00 67.57  ? 124 GLU A OE1 1 
ATOM 722   O OE2 . GLU A 1 124 ? -3.472  -36.971 5.698   1.00 62.57  ? 124 GLU A OE2 1 
ATOM 723   N N   . ILE A 1 125 ? 0.109   -32.879 9.047   1.00 45.40  ? 125 ILE A N   1 
ATOM 724   C CA  . ILE A 1 125 ? 1.397   -32.513 9.701   1.00 39.93  ? 125 ILE A CA  1 
ATOM 725   C C   . ILE A 1 125 ? 1.280   -31.105 10.277  1.00 45.51  ? 125 ILE A C   1 
ATOM 726   O O   . ILE A 1 125 ? 1.907   -30.835 11.309  1.00 44.81  ? 125 ILE A O   1 
ATOM 727   C CB  . ILE A 1 125 ? 2.558   -32.627 8.696   1.00 42.87  ? 125 ILE A CB  1 
ATOM 728   C CG1 . ILE A 1 125 ? 3.124   -34.047 8.634   1.00 43.18  ? 125 ILE A CG1 1 
ATOM 729   C CG2 . ILE A 1 125 ? 3.646   -31.611 9.003   1.00 45.60  ? 125 ILE A CG2 1 
ATOM 730   C CD1 . ILE A 1 125 ? 2.218   -35.041 7.949   1.00 47.57  ? 125 ILE A CD1 1 
ATOM 731   N N   . ALA A 1 126 ? 0.494   -30.247 9.635   1.00 43.99  ? 126 ALA A N   1 
ATOM 732   C CA  . ALA A 1 126 ? 0.308   -28.866 10.129  1.00 46.00  ? 126 ALA A CA  1 
ATOM 733   C C   . ALA A 1 126 ? -0.442  -28.889 11.459  1.00 46.27  ? 126 ALA A C   1 
ATOM 734   O O   . ALA A 1 126 ? -0.109  -28.098 12.350  1.00 38.35  ? 126 ALA A O   1 
ATOM 735   C CB  . ALA A 1 126 ? -0.452  -28.090 9.101   1.00 35.18  ? 126 ALA A CB  1 
ATOM 736   N N   . SER A 1 127 ? -1.431  -29.764 11.566  1.00 44.89  ? 127 SER A N   1 
ATOM 737   C CA  . SER A 1 127 ? -2.234  -29.867 12.803  1.00 46.93  ? 127 SER A CA  1 
ATOM 738   C C   . SER A 1 127 ? -1.408  -30.505 13.922  1.00 48.06  ? 127 SER A C   1 
ATOM 739   O O   . SER A 1 127 ? -1.720  -30.262 15.089  1.00 45.30  ? 127 SER A O   1 
ATOM 740   C CB  . SER A 1 127 ? -3.478  -30.642 12.517  1.00 52.43  ? 127 SER A CB  1 
ATOM 741   O OG  . SER A 1 127 ? -4.121  -30.137 11.359  1.00 63.27  ? 127 SER A OG  1 
ATOM 742   N N   . SER A 1 128 ? -0.412  -31.304 13.568  1.00 47.07  ? 128 SER A N   1 
ATOM 743   C CA  . SER A 1 128 ? 0.476   -31.918 14.576  1.00 39.43  ? 128 SER A CA  1 
ATOM 744   C C   . SER A 1 128 ? 1.396   -30.847 15.153  1.00 43.96  ? 128 SER A C   1 
ATOM 745   O O   . SER A 1 128 ? 2.038   -31.106 16.173  1.00 51.12  ? 128 SER A O   1 
ATOM 746   C CB  . SER A 1 128 ? 1.255   -33.018 13.959  1.00 45.68  ? 128 SER A CB  1 
ATOM 747   O OG  . SER A 1 128 ? 2.190   -32.508 13.026  1.00 47.59  ? 128 SER A OG  1 
ATOM 748   N N   . HIS A 1 129 ? 1.483   -29.699 14.499  1.00 40.53  ? 129 HIS A N   1 
ATOM 749   C CA  . HIS A 1 129 ? 2.273   -28.580 15.063  1.00 40.79  ? 129 HIS A CA  1 
ATOM 750   C C   . HIS A 1 129 ? 1.292   -27.491 15.499  1.00 46.76  ? 129 HIS A C   1 
ATOM 751   O O   . HIS A 1 129 ? 1.739   -26.370 15.799  1.00 43.55  ? 129 HIS A O   1 
ATOM 752   C CB  . HIS A 1 129 ? 3.306   -28.087 14.050  1.00 40.67  ? 129 HIS A CB  1 
ATOM 753   C CG  . HIS A 1 129 ? 4.313   -29.094 13.607  1.00 40.30  ? 129 HIS A CG  1 
ATOM 754   N ND1 . HIS A 1 129 ? 5.653   -28.968 13.898  1.00 34.98  ? 129 HIS A ND1 1 
ATOM 755   C CD2 . HIS A 1 129 ? 4.191   -30.223 12.908  1.00 46.38  ? 129 HIS A CD2 1 
ATOM 756   C CE1 . HIS A 1 129 ? 6.306   -29.996 13.384  1.00 38.17  ? 129 HIS A CE1 1 
ATOM 757   N NE2 . HIS A 1 129 ? 5.437   -30.770 12.779  1.00 38.59  ? 129 HIS A NE2 1 
ATOM 758   N N   . ASN A 1 130 ? -0.004  -27.811 15.525  1.00 48.02  ? 130 ASN A N   1 
ATOM 759   C CA  . ASN A 1 130 ? -1.060  -26.850 15.939  1.00 40.39  ? 130 ASN A CA  1 
ATOM 760   C C   . ASN A 1 130 ? -1.022  -25.663 14.985  1.00 39.68  ? 130 ASN A C   1 
ATOM 761   O O   . ASN A 1 130 ? -1.210  -24.533 15.448  1.00 41.87  ? 130 ASN A O   1 
ATOM 762   C CB  . ASN A 1 130 ? -0.930  -26.493 17.420  1.00 48.97  ? 130 ASN A CB  1 
ATOM 763   C CG  . ASN A 1 130 ? -2.190  -25.890 18.007  1.00 61.12  ? 130 ASN A CG  1 
ATOM 764   O OD1 . ASN A 1 130 ? -3.254  -26.503 17.963  1.00 74.49  ? 130 ASN A OD1 1 
ATOM 765   N ND2 . ASN A 1 130 ? -2.076  -24.697 18.564  1.00 57.81  ? 130 ASN A ND2 1 
ATOM 766   N N   . ILE A 1 131 ? -0.793  -25.929 13.698  1.00 43.17  ? 131 ILE A N   1 
ATOM 767   C CA  . ILE A 1 131 ? -0.795  -24.861 12.704  1.00 34.18  ? 131 ILE A CA  1 
ATOM 768   C C   . ILE A 1 131 ? -2.089  -24.964 11.905  1.00 31.66  ? 131 ILE A C   1 
ATOM 769   O O   . ILE A 1 131 ? -2.352  -26.016 11.306  1.00 31.17  ? 131 ILE A O   1 
ATOM 770   C CB  . ILE A 1 131 ? 0.429   -24.940 11.782  1.00 33.81  ? 131 ILE A CB  1 
ATOM 771   C CG1 . ILE A 1 131 ? 1.720   -24.845 12.592  1.00 37.63  ? 131 ILE A CG1 1 
ATOM 772   C CG2 . ILE A 1 131 ? 0.385   -23.833 10.740  1.00 46.07  ? 131 ILE A CG2 1 
ATOM 773   C CD1 . ILE A 1 131 ? 2.962   -24.905 11.743  1.00 38.45  ? 131 ILE A CD1 1 
ATOM 774   N N   . PRO A 1 132 ? -2.914  -23.921 11.863  1.00 31.36  ? 132 PRO A N   1 
ATOM 775   C CA  . PRO A 1 132 ? -4.121  -23.976 11.030  1.00 42.77  ? 132 PRO A CA  1 
ATOM 776   C C   . PRO A 1 132 ? -3.762  -24.019 9.553   1.00 37.80  ? 132 PRO A C   1 
ATOM 777   O O   . PRO A 1 132 ? -2.878  -23.301 9.086   1.00 41.08  ? 132 PRO A O   1 
ATOM 778   C CB  . PRO A 1 132 ? -4.863  -22.684 11.391  1.00 34.61  ? 132 PRO A CB  1 
ATOM 779   C CG  . PRO A 1 132 ? -3.795  -21.767 11.886  1.00 39.10  ? 132 PRO A CG  1 
ATOM 780   C CD  . PRO A 1 132 ? -2.794  -22.643 12.582  1.00 35.32  ? 132 PRO A CD  1 
ATOM 781   N N   . ALA A 1 133 ? -4.461  -24.880 8.821   1.00 28.97  ? 133 ALA A N   1 
ATOM 782   C CA  . ALA A 1 133 ? -4.175  -25.142 7.416   1.00 29.60  ? 133 ALA A CA  1 
ATOM 783   C C   . ALA A 1 133 ? -5.309  -24.613 6.548   1.00 32.26  ? 133 ALA A C   1 
ATOM 784   O O   . ALA A 1 133 ? -6.478  -24.941 6.778   1.00 35.91  ? 133 ALA A O   1 
ATOM 785   C CB  . ALA A 1 133 ? -3.975  -26.638 7.177   1.00 28.99  ? 133 ALA A CB  1 
ATOM 786   N N   . VAL A 1 134 ? -4.959  -23.799 5.554   1.00 30.44  ? 134 VAL A N   1 
ATOM 787   C CA  . VAL A 1 134 ? -5.912  -23.229 4.607   1.00 34.69  ? 134 VAL A CA  1 
ATOM 788   C C   . VAL A 1 134 ? -5.565  -23.731 3.212   1.00 32.88  ? 134 VAL A C   1 
ATOM 789   O O   . VAL A 1 134 ? -4.393  -23.744 2.821   1.00 38.21  ? 134 VAL A O   1 
ATOM 790   C CB  . VAL A 1 134 ? -5.904  -21.686 4.647   1.00 40.32  ? 134 VAL A CB  1 
ATOM 791   C CG1 . VAL A 1 134 ? -6.754  -21.113 3.520   1.00 35.74  ? 134 VAL A CG1 1 
ATOM 792   C CG2 . VAL A 1 134 ? -6.395  -21.186 5.998   1.00 41.22  ? 134 VAL A CG2 1 
ATOM 793   N N   . TYR A 1 135 ? -6.587  -24.136 2.463   1.00 35.30  ? 135 TYR A N   1 
ATOM 794   C CA  . TYR A 1 135 ? -6.400  -24.688 1.126   1.00 29.02  ? 135 TYR A CA  1 
ATOM 795   C C   . TYR A 1 135 ? -6.452  -23.589 0.072   1.00 26.16  ? 135 TYR A C   1 
ATOM 796   O O   . TYR A 1 135 ? -7.247  -22.648 0.168   1.00 31.21  ? 135 TYR A O   1 
ATOM 797   C CB  . TYR A 1 135 ? -7.466  -25.749 0.840   1.00 33.55  ? 135 TYR A CB  1 
ATOM 798   C CG  . TYR A 1 135 ? -7.493  -26.265 -0.583  1.00 39.56  ? 135 TYR A CG  1 
ATOM 799   C CD1 . TYR A 1 135 ? -6.386  -26.887 -1.144  1.00 40.77  ? 135 TYR A CD1 1 
ATOM 800   C CD2 . TYR A 1 135 ? -8.643  -26.159 -1.356  1.00 34.46  ? 135 TYR A CD2 1 
ATOM 801   C CE1 . TYR A 1 135 ? -6.416  -27.368 -2.442  1.00 40.36  ? 135 TYR A CE1 1 
ATOM 802   C CE2 . TYR A 1 135 ? -8.684  -26.639 -2.649  1.00 37.55  ? 135 TYR A CE2 1 
ATOM 803   C CZ  . TYR A 1 135 ? -7.571  -27.244 -3.189  1.00 43.39  ? 135 TYR A CZ  1 
ATOM 804   O OH  . TYR A 1 135 ? -7.606  -27.722 -4.480  1.00 30.55  ? 135 TYR A OH  1 
ATOM 805   N N   . PHE A 1 136 ? -5.594  -23.717 -0.937  1.00 28.76  ? 136 PHE A N   1 
ATOM 806   C CA  . PHE A 1 136 ? -5.511  -22.779 -2.052  1.00 36.85  ? 136 PHE A CA  1 
ATOM 807   C C   . PHE A 1 136 ? -5.927  -23.518 -3.318  1.00 36.84  ? 136 PHE A C   1 
ATOM 808   O O   . PHE A 1 136 ? -5.210  -24.406 -3.789  1.00 38.49  ? 136 PHE A O   1 
ATOM 809   C CB  . PHE A 1 136 ? -4.099  -22.211 -2.185  1.00 39.52  ? 136 PHE A CB  1 
ATOM 810   C CG  . PHE A 1 136 ? -3.966  -21.118 -3.212  1.00 38.08  ? 136 PHE A CG  1 
ATOM 811   C CD1 . PHE A 1 136 ? -5.081  -20.443 -3.686  1.00 38.64  ? 136 PHE A CD1 1 
ATOM 812   C CD2 . PHE A 1 136 ? -2.721  -20.769 -3.709  1.00 38.85  ? 136 PHE A CD2 1 
ATOM 813   C CE1 . PHE A 1 136 ? -4.953  -19.443 -4.633  1.00 40.01  ? 136 PHE A CE1 1 
ATOM 814   C CE2 . PHE A 1 136 ? -2.589  -19.772 -4.654  1.00 37.30  ? 136 PHE A CE2 1 
ATOM 815   C CZ  . PHE A 1 136 ? -3.706  -19.108 -5.118  1.00 40.09  ? 136 PHE A CZ  1 
ATOM 816   N N   . LEU A 1 137 ? -7.079  -23.146 -3.872  1.00 35.05  ? 137 LEU A N   1 
ATOM 817   C CA  . LEU A 1 137 ? -7.603  -23.749 -5.091  1.00 34.06  ? 137 LEU A CA  1 
ATOM 818   C C   . LEU A 1 137 ? -7.268  -22.831 -6.263  1.00 33.30  ? 137 LEU A C   1 
ATOM 819   O O   . LEU A 1 137 ? -7.740  -21.692 -6.319  1.00 31.04  ? 137 LEU A O   1 
ATOM 820   C CB  . LEU A 1 137 ? -9.111  -23.970 -4.980  1.00 37.48  ? 137 LEU A CB  1 
ATOM 821   C CG  . LEU A 1 137 ? -9.833  -24.580 -6.180  1.00 31.40  ? 137 LEU A CG  1 
ATOM 822   C CD1 . LEU A 1 137 ? -9.864  -26.098 -6.088  1.00 35.58  ? 137 LEU A CD1 1 
ATOM 823   C CD2 . LEU A 1 137 ? -11.237 -24.014 -6.291  1.00 40.52  ? 137 LEU A CD2 1 
ATOM 824   N N   . THR A 1 138 ? -6.453  -23.327 -7.192  1.00 33.51  ? 138 THR A N   1 
ATOM 825   C CA  . THR A 1 138 ? -6.032  -22.550 -8.351  1.00 39.53  ? 138 THR A CA  1 
ATOM 826   C C   . THR A 1 138 ? -6.877  -22.832 -9.583  1.00 33.94  ? 138 THR A C   1 
ATOM 827   O O   . THR A 1 138 ? -6.485  -22.456 -10.691 1.00 30.64  ? 138 THR A O   1 
ATOM 828   C CB  . THR A 1 138 ? -4.560  -22.823 -8.667  1.00 27.63  ? 138 THR A CB  1 
ATOM 829   O OG1 . THR A 1 138 ? -4.393  -24.201 -9.020  1.00 34.29  ? 138 THR A OG1 1 
ATOM 830   C CG2 . THR A 1 138 ? -3.697  -22.511 -7.452  1.00 30.45  ? 138 THR A CG2 1 
ATOM 831   N N   . THR A 1 139 ? -8.023  -23.481 -9.410  1.00 39.88  ? 139 THR A N   1 
ATOM 832   C CA  . THR A 1 139 ? -8.910  -23.852 -10.498 1.00 32.52  ? 139 THR A CA  1 
ATOM 833   C C   . THR A 1 139 ? -10.248 -23.142 -10.311 1.00 30.73  ? 139 THR A C   1 
ATOM 834   O O   . THR A 1 139 ? -10.556 -22.636 -9.229  1.00 30.60  ? 139 THR A O   1 
ATOM 835   C CB  . THR A 1 139 ? -9.092  -25.379 -10.540 1.00 41.08  ? 139 THR A CB  1 
ATOM 836   O OG1 . THR A 1 139 ? -7.814  -26.011 -10.395 1.00 36.25  ? 139 THR A OG1 1 
ATOM 837   C CG2 . THR A 1 139 ? -9.707  -25.828 -11.853 1.00 57.01  ? 139 THR A CG2 1 
ATOM 838   N N   . ALA A 1 140 ? -11.025 -23.086 -11.390 1.00 28.25  ? 140 ALA A N   1 
ATOM 839   C CA  . ALA A 1 140 ? -12.353 -22.489 -11.334 1.00 33.22  ? 140 ALA A CA  1 
ATOM 840   C C   . ALA A 1 140 ? -13.216 -23.183 -10.287 1.00 35.14  ? 140 ALA A C   1 
ATOM 841   O O   . ALA A 1 140 ? -13.056 -24.375 -10.004 1.00 31.52  ? 140 ALA A O   1 
ATOM 842   C CB  . ALA A 1 140 ? -13.029 -22.573 -12.702 1.00 42.23  ? 140 ALA A CB  1 
ATOM 843   N N   . ALA A 1 141 ? -14.145 -22.421 -9.708  1.00 35.39  ? 141 ALA A N   1 
ATOM 844   C CA  . ALA A 1 141 ? -15.003 -22.967 -8.664  1.00 47.64  ? 141 ALA A CA  1 
ATOM 845   C C   . ALA A 1 141 ? -16.020 -23.956 -9.221  1.00 44.68  ? 141 ALA A C   1 
ATOM 846   O O   . ALA A 1 141 ? -16.395 -24.904 -8.526  1.00 42.79  ? 141 ALA A O   1 
ATOM 847   C CB  . ALA A 1 141 ? -15.717 -21.839 -7.922  1.00 45.15  ? 141 ALA A CB  1 
ATOM 848   N N   . ALA A 1 142 ? -16.474 -23.761 -10.463 1.00 30.75  ? 142 ALA A N   1 
ATOM 849   C CA  . ALA A 1 142 ? -17.514 -24.624 -11.017 1.00 41.93  ? 142 ALA A CA  1 
ATOM 850   C C   . ALA A 1 142 ? -16.997 -26.032 -11.279 1.00 48.53  ? 142 ALA A C   1 
ATOM 851   O O   . ALA A 1 142 ? -17.681 -27.024 -10.981 1.00 49.57  ? 142 ALA A O   1 
ATOM 852   C CB  . ALA A 1 142 ? -18.061 -24.015 -12.308 1.00 40.87  ? 142 ALA A CB  1 
ATOM 853   N N   . SER A 1 143 ? -15.801 -26.136 -11.862 1.00 47.65  ? 143 SER A N   1 
ATOM 854   C CA  . SER A 1 143 ? -15.238 -27.440 -12.188 1.00 49.81  ? 143 SER A CA  1 
ATOM 855   C C   . SER A 1 143 ? -15.073 -28.295 -10.939 1.00 43.96  ? 143 SER A C   1 
ATOM 856   O O   . SER A 1 143 ? -15.322 -29.505 -10.970 1.00 57.51  ? 143 SER A O   1 
ATOM 857   C CB  . SER A 1 143 ? -13.903 -27.260 -12.906 1.00 52.91  ? 143 SER A CB  1 
ATOM 858   O OG  . SER A 1 143 ? -14.046 -26.380 -14.009 1.00 65.46  ? 143 SER A OG  1 
ATOM 859   N N   . SER A 1 144 ? -14.662 -27.681 -9.827  1.00 39.77  ? 144 SER A N   1 
ATOM 860   C CA  . SER A 1 144 ? -14.565 -28.415 -8.570  1.00 46.96  ? 144 SER A CA  1 
ATOM 861   C C   . SER A 1 144 ? -15.940 -28.662 -7.963  1.00 42.23  ? 144 SER A C   1 
ATOM 862   O O   . SER A 1 144 ? -16.166 -29.703 -7.333  1.00 42.44  ? 144 SER A O   1 
ATOM 863   C CB  . SER A 1 144 ? -13.684 -27.651 -7.584  1.00 49.22  ? 144 SER A CB  1 
ATOM 864   O OG  . SER A 1 144 ? -12.448 -27.292 -8.178  1.00 48.51  ? 144 SER A OG  1 
ATOM 865   N N   . SER A 1 145 ? -16.857 -27.702 -8.138  1.00 42.40  ? 145 SER A N   1 
ATOM 866   C CA  . SER A 1 145 ? -18.222 -27.847 -7.645  1.00 41.13  ? 145 SER A CA  1 
ATOM 867   C C   . SER A 1 145 ? -18.894 -29.077 -8.222  1.00 50.67  ? 145 SER A C   1 
ATOM 868   O O   . SER A 1 145 ? -19.705 -29.710 -7.540  1.00 55.57  ? 145 SER A O   1 
ATOM 869   C CB  . SER A 1 145 ? -19.032 -26.595 -7.982  1.00 34.57  ? 145 SER A CB  1 
ATOM 870   O OG  . SER A 1 145 ? -18.474 -25.448 -7.366  1.00 54.66  ? 145 SER A OG  1 
ATOM 871   N N   . ILE A 1 146 ? -18.573 -29.428 -9.467  1.00 48.51  ? 146 ILE A N   1 
ATOM 872   C CA  . ILE A 1 146 ? -19.095 -30.644 -10.091 1.00 42.36  ? 146 ILE A CA  1 
ATOM 873   C C   . ILE A 1 146 ? -18.904 -31.831 -9.151  1.00 49.04  ? 146 ILE A C   1 
ATOM 874   O O   . ILE A 1 146 ? -19.875 -32.393 -8.621  1.00 48.37  ? 146 ILE A O   1 
ATOM 875   C CB  . ILE A 1 146 ? -18.416 -30.910 -11.448 1.00 46.21  ? 146 ILE A CB  1 
ATOM 876   C CG1 . ILE A 1 146 ? -18.596 -29.714 -12.386 1.00 53.70  ? 146 ILE A CG1 1 
ATOM 877   C CG2 . ILE A 1 146 ? -18.976 -32.169 -12.087 1.00 40.95  ? 146 ILE A CG2 1 
ATOM 878   C CD1 . ILE A 1 146 ? -20.034 -29.325 -12.612 1.00 57.65  ? 146 ILE A CD1 1 
ATOM 879   N N   . GLY A 1 147 ? -17.643 -32.202 -8.916  1.00 51.54  ? 147 GLY A N   1 
ATOM 880   C CA  . GLY A 1 147 ? -17.358 -33.354 -8.078  1.00 47.45  ? 147 GLY A CA  1 
ATOM 881   C C   . GLY A 1 147 ? -17.747 -33.167 -6.625  1.00 46.18  ? 147 GLY A C   1 
ATOM 882   O O   . GLY A 1 147 ? -18.181 -34.121 -5.967  1.00 59.66  ? 147 GLY A O   1 
ATOM 883   N N   . LEU A 1 148 ? -17.604 -31.949 -6.096  1.00 44.66  ? 148 LEU A N   1 
ATOM 884   C CA  . LEU A 1 148 ? -17.942 -31.742 -4.691  1.00 48.80  ? 148 LEU A CA  1 
ATOM 885   C C   . LEU A 1 148 ? -19.437 -31.924 -4.456  1.00 51.92  ? 148 LEU A C   1 
ATOM 886   O O   . LEU A 1 148 ? -19.848 -32.457 -3.417  1.00 45.39  ? 148 LEU A O   1 
ATOM 887   C CB  . LEU A 1 148 ? -17.490 -30.361 -4.227  1.00 35.43  ? 148 LEU A CB  1 
ATOM 888   C CG  . LEU A 1 148 ? -17.352 -30.219 -2.710  1.00 36.52  ? 148 LEU A CG  1 
ATOM 889   C CD1 . LEU A 1 148 ? -16.456 -31.313 -2.147  1.00 44.46  ? 148 LEU A CD1 1 
ATOM 890   C CD2 . LEU A 1 148 ? -16.808 -28.847 -2.352  1.00 43.32  ? 148 LEU A CD2 1 
ATOM 891   N N   . HIS A 1 149 ? -20.283 -31.554 -5.419  1.00 49.13  ? 149 HIS A N   1 
ATOM 892   C CA  . HIS A 1 149 ? -21.753 -31.763 -5.278  1.00 49.30  ? 149 HIS A CA  1 
ATOM 893   C C   . HIS A 1 149 ? -22.077 -33.246 -5.335  1.00 45.27  ? 149 HIS A C   1 
ATOM 894   O O   . HIS A 1 149 ? -22.910 -33.689 -4.563  1.00 41.78  ? 149 HIS A O   1 
ATOM 895   C CB  . HIS A 1 149 ? -22.518 -31.063 -6.402  1.00 41.83  ? 149 HIS A CB  1 
ATOM 896   C CG  . HIS A 1 149 ? -23.994 -31.243 -6.365  1.00 45.36  ? 149 HIS A CG  1 
ATOM 897   N ND1 . HIS A 1 149 ? -24.821 -30.361 -5.711  1.00 44.72  ? 149 HIS A ND1 1 
ATOM 898   C CD2 . HIS A 1 149 ? -24.793 -32.180 -6.910  1.00 45.86  ? 149 HIS A CD2 1 
ATOM 899   C CE1 . HIS A 1 149 ? -26.067 -30.754 -5.841  1.00 53.83  ? 149 HIS A CE1 1 
ATOM 900   N NE2 . HIS A 1 149 ? -26.074 -31.869 -6.565  1.00 53.25  ? 149 HIS A NE2 1 
ATOM 901   N N   . ALA A 1 150 ? -21.404 -33.970 -6.207  1.00 45.76  ? 150 ALA A N   1 
ATOM 902   C CA  . ALA A 1 150 ? -21.694 -35.401 -6.412  1.00 43.73  ? 150 ALA A CA  1 
ATOM 903   C C   . ALA A 1 150 ? -21.438 -36.173 -5.127  1.00 45.00  ? 150 ALA A C   1 
ATOM 904   O O   . ALA A 1 150 ? -21.951 -37.285 -4.997  1.00 57.31  ? 150 ALA A O   1 
ATOM 905   C CB  . ALA A 1 150 ? -20.823 -35.914 -7.514  1.00 37.06  ? 150 ALA A CB  1 
ATOM 906   N N   . PHE A 1 151 ? -20.669 -35.576 -4.211  1.00 50.42  ? 151 PHE A N   1 
ATOM 907   C CA  . PHE A 1 151 ? -20.386 -36.215 -2.901  1.00 53.68  ? 151 PHE A CA  1 
ATOM 908   C C   . PHE A 1 151 ? -21.325 -35.617 -1.851  1.00 47.55  ? 151 PHE A C   1 
ATOM 909   O O   . PHE A 1 151 ? -21.997 -36.389 -1.139  1.00 60.61  ? 151 PHE A O   1 
ATOM 910   C CB  . PHE A 1 151 ? -18.920 -36.001 -2.521  1.00 53.11  ? 151 PHE A CB  1 
ATOM 911   C CG  . PHE A 1 151 ? -18.579 -36.351 -1.095  1.00 51.78  ? 151 PHE A CG  1 
ATOM 912   C CD1 . PHE A 1 151 ? -18.736 -37.644 -0.624  1.00 59.06  ? 151 PHE A CD1 1 
ATOM 913   C CD2 . PHE A 1 151 ? -18.107 -35.384 -0.222  1.00 58.73  ? 151 PHE A CD2 1 
ATOM 914   C CE1 . PHE A 1 151 ? -18.423 -37.962 0.686   1.00 63.72  ? 151 PHE A CE1 1 
ATOM 915   C CE2 . PHE A 1 151 ? -17.797 -35.705 1.090   1.00 61.33  ? 151 PHE A CE2 1 
ATOM 916   C CZ  . PHE A 1 151 ? -17.955 -36.993 1.542   1.00 54.36  ? 151 PHE A CZ  1 
ATOM 917   N N   . LYS A 1 152 ? -21.298 -34.312 -1.682  1.00 40.14  ? 152 LYS A N   1 
ATOM 918   C CA  . LYS A 1 152 ? -22.107 -33.771 -0.570  1.00 44.59  ? 152 LYS A CA  1 
ATOM 919   C C   . LYS A 1 152 ? -23.570 -34.139 -0.805  1.00 55.04  ? 152 LYS A C   1 
ATOM 920   O O   . LYS A 1 152 ? -24.215 -34.634 0.134   1.00 48.40  ? 152 LYS A O   1 
ATOM 921   C CB  . LYS A 1 152 ? -21.808 -32.287 -0.366  1.00 42.78  ? 152 LYS A CB  1 
ATOM 922   C CG  . LYS A 1 152 ? -20.354 -31.963 -0.069  1.00 47.65  ? 152 LYS A CG  1 
ATOM 923   C CD  . LYS A 1 152 ? -19.885 -32.514 1.254   1.00 51.65  ? 152 LYS A CD  1 
ATOM 924   C CE  . LYS A 1 152 ? -18.416 -32.263 1.502   1.00 56.91  ? 152 LYS A CE  1 
ATOM 925   N NZ  . LYS A 1 152 ? -18.035 -30.874 1.160   1.00 65.43  ? 152 LYS A NZ  1 
ATOM 926   N N   . ASN A 1 153 ? -24.066 -33.902 -2.013  1.00 52.89  ? 153 ASN A N   1 
ATOM 927   C CA  . ASN A 1 153 ? -25.489 -34.180 -2.320  1.00 47.76  ? 153 ASN A CA  1 
ATOM 928   C C   . ASN A 1 153 ? -25.490 -35.238 -3.416  1.00 59.28  ? 153 ASN A C   1 
ATOM 929   O O   . ASN A 1 153 ? -25.533 -34.868 -4.594  1.00 62.21  ? 153 ASN A O   1 
ATOM 930   C CB  . ASN A 1 153 ? -26.183 -32.873 -2.691  1.00 44.37  ? 153 ASN A CB  1 
ATOM 931   C CG  . ASN A 1 153 ? -26.060 -31.822 -1.612  1.00 45.38  ? 153 ASN A CG  1 
ATOM 932   O OD1 . ASN A 1 153 ? -26.089 -32.135 -0.426  1.00 43.38  ? 153 ASN A OD1 1 
ATOM 933   N ND2 . ASN A 1 153 ? -25.930 -30.570 -2.014  1.00 57.99  ? 153 ASN A ND2 1 
ATOM 934   N N   . PRO A 1 154 ? -25.566 -36.541 -3.089  1.00 64.94  ? 154 PRO A N   1 
ATOM 935   C CA  . PRO A 1 154 ? -25.392 -37.571 -4.108  1.00 66.76  ? 154 PRO A CA  1 
ATOM 936   C C   . PRO A 1 154 ? -26.358 -37.565 -5.297  1.00 71.27  ? 154 PRO A C   1 
ATOM 937   O O   . PRO A 1 154 ? -25.889 -37.701 -6.399  1.00 80.76  ? 154 PRO A O   1 
ATOM 938   C CB  . PRO A 1 154 ? -25.634 -38.863 -3.320  1.00 63.39  ? 154 PRO A CB  1 
ATOM 939   C CG  . PRO A 1 154 ? -25.291 -38.501 -1.896  1.00 66.75  ? 154 PRO A CG  1 
ATOM 940   C CD  . PRO A 1 154 ? -25.781 -37.079 -1.750  1.00 70.57  ? 154 PRO A CD  1 
ATOM 941   N N   . GLY A 1 155 ? -27.652 -37.400 -5.057  1.00 60.55  ? 155 GLY A N   1 
ATOM 942   C CA  . GLY A 1 155 ? -28.609 -37.493 -6.172  1.00 62.20  ? 155 GLY A CA  1 
ATOM 943   C C   . GLY A 1 155 ? -29.456 -36.245 -6.314  1.00 76.43  ? 155 GLY A C   1 
ATOM 944   O O   . GLY A 1 155 ? -30.616 -36.381 -6.758  1.00 86.28  ? 155 GLY A O   1 
ATOM 945   N N   . GLU A 1 156 ? -28.940 -35.080 -5.924  1.00 64.24  ? 156 GLU A N   1 
ATOM 946   C CA  . GLU A 1 156 ? -29.800 -33.867 -5.916  1.00 58.43  ? 156 GLU A CA  1 
ATOM 947   C C   . GLU A 1 156 ? -29.703 -33.079 -7.225  1.00 69.15  ? 156 GLU A C   1 
ATOM 948   O O   . GLU A 1 156 ? -30.354 -32.021 -7.285  1.00 80.62  ? 156 GLU A O   1 
ATOM 949   C CB  . GLU A 1 156 ? -29.580 -33.035 -4.648  1.00 55.56  ? 156 GLU A CB  1 
ATOM 950   C CG  . GLU A 1 156 ? -30.198 -33.649 -3.403  1.00 58.09  ? 156 GLU A CG  1 
ATOM 951   C CD  . GLU A 1 156 ? -30.344 -32.706 -2.222  1.00 65.59  ? 156 GLU A CD  1 
ATOM 952   O OE1 . GLU A 1 156 ? -29.715 -31.632 -2.242  1.00 65.38  ? 156 GLU A OE1 1 
ATOM 953   O OE2 . GLU A 1 156 ? -31.099 -33.040 -1.285  1.00 69.86  ? 156 GLU A OE2 1 
ATOM 954   N N   . LYS A 1 157 ? -28.861 -33.498 -8.170  1.00 61.46  ? 157 LYS A N   1 
ATOM 955   C CA  . LYS A 1 157 ? -28.765 -32.854 -9.513  1.00 68.44  ? 157 LYS A CA  1 
ATOM 956   C C   . LYS A 1 157 ? -27.935 -31.579 -9.388  1.00 67.18  ? 157 LYS A C   1 
ATOM 957   O O   . LYS A 1 157 ? -28.139 -30.848 -8.421  1.00 68.96  ? 157 LYS A O   1 
ATOM 958   C CB  . LYS A 1 157 ? -30.124 -32.575 -10.160 1.00 58.22  ? 157 LYS A CB  1 
ATOM 959   C CG  . LYS A 1 157 ? -30.078 -31.897 -11.521 1.00 75.20  ? 157 LYS A CG  1 
ATOM 960   C CD  . LYS A 1 157 ? -29.377 -32.712 -12.585 1.00 79.90  ? 157 LYS A CD  1 
ATOM 961   C CE  . LYS A 1 157 ? -29.477 -32.117 -13.973 1.00 80.99  ? 157 LYS A CE  1 
ATOM 962   N NZ  . LYS A 1 157 ? -28.603 -32.827 -14.937 1.00 91.81  ? 157 LYS A NZ  1 
ATOM 963   N N   . TYR A 1 158 ? -27.127 -31.266 -10.390 1.00 66.37  ? 158 TYR A N   1 
ATOM 964   C CA  . TYR A 1 158 ? -26.374 -29.995 -10.325 1.00 59.87  ? 158 TYR A CA  1 
ATOM 965   C C   . TYR A 1 158 ? -27.382 -28.857 -10.385 1.00 56.71  ? 158 TYR A C   1 
ATOM 966   O O   . TYR A 1 158 ? -28.339 -28.946 -11.155 1.00 46.67  ? 158 TYR A O   1 
ATOM 967   C CB  . TYR A 1 158 ? -25.291 -29.938 -11.402 1.00 59.71  ? 158 TYR A CB  1 
ATOM 968   C CG  . TYR A 1 158 ? -24.198 -28.936 -11.157 1.00 60.67  ? 158 TYR A CG  1 
ATOM 969   C CD1 . TYR A 1 158 ? -23.269 -29.126 -10.148 1.00 50.05  ? 158 TYR A CD1 1 
ATOM 970   C CD2 . TYR A 1 158 ? -24.086 -27.802 -11.938 1.00 56.51  ? 158 TYR A CD2 1 
ATOM 971   C CE1 . TYR A 1 158 ? -22.264 -28.207 -9.913  1.00 46.41  ? 158 TYR A CE1 1 
ATOM 972   C CE2 . TYR A 1 158 ? -23.081 -26.879 -11.723 1.00 50.68  ? 158 TYR A CE2 1 
ATOM 973   C CZ  . TYR A 1 158 ? -22.169 -27.079 -10.705 1.00 46.28  ? 158 TYR A CZ  1 
ATOM 974   O OH  . TYR A 1 158 ? -21.182 -26.165 -10.496 1.00 56.93  ? 158 TYR A OH  1 
ATOM 975   N N   . PRO A 1 159 ? -27.165 -27.764 -9.634  1.00 61.62  ? 159 PRO A N   1 
ATOM 976   C CA  . PRO A 1 159 ? -28.118 -26.667 -9.574  1.00 60.13  ? 159 PRO A CA  1 
ATOM 977   C C   . PRO A 1 159 ? -28.353 -25.981 -10.922 1.00 61.09  ? 159 PRO A C   1 
ATOM 978   O O   . PRO A 1 159 ? -29.273 -25.202 -10.994 1.00 55.81  ? 159 PRO A O   1 
ATOM 979   C CB  . PRO A 1 159 ? -27.454 -25.726 -8.571  1.00 51.03  ? 159 PRO A CB  1 
ATOM 980   C CG  . PRO A 1 159 ? -26.687 -26.644 -7.675  1.00 49.04  ? 159 PRO A CG  1 
ATOM 981   C CD  . PRO A 1 159 ? -26.082 -27.609 -8.663  1.00 54.12  ? 159 PRO A CD  1 
ATOM 982   N N   . PHE A 1 160 ? -27.502 -26.245 -11.920 1.00 60.75  ? 160 PHE A N   1 
ATOM 983   C CA  . PHE A 1 160 ? -27.636 -25.601 -13.254 1.00 57.39  ? 160 PHE A CA  1 
ATOM 984   C C   . PHE A 1 160 ? -27.546 -26.613 -14.411 1.00 61.47  ? 160 PHE A C   1 
ATOM 985   O O   . PHE A 1 160 ? -26.383 -26.915 -14.719 1.00 55.46  ? 160 PHE A O   1 
ATOM 986   C CB  . PHE A 1 160 ? -26.485 -24.607 -13.379 1.00 50.03  ? 160 PHE A CB  1 
ATOM 987   C CG  . PHE A 1 160 ? -26.147 -23.915 -12.079 1.00 52.51  ? 160 PHE A CG  1 
ATOM 988   C CD1 . PHE A 1 160 ? -27.026 -23.018 -11.498 1.00 58.66  ? 160 PHE A CD1 1 
ATOM 989   C CD2 . PHE A 1 160 ? -24.963 -24.183 -11.418 1.00 58.60  ? 160 PHE A CD2 1 
ATOM 990   C CE1 . PHE A 1 160 ? -26.735 -22.418 -10.285 1.00 53.86  ? 160 PHE A CE1 1 
ATOM 991   C CE2 . PHE A 1 160 ? -24.663 -23.568 -10.212 1.00 56.53  ? 160 PHE A CE2 1 
ATOM 992   C CZ  . PHE A 1 160 ? -25.551 -22.691 -9.644  1.00 44.73  ? 160 PHE A CZ  1 
ATOM 993   N N   . PRO A 1 161 ? -28.625 -27.128 -15.098 1.00 63.07  ? 161 PRO A N   1 
ATOM 994   C CA  . PRO A 1 161 ? -28.392 -28.046 -16.221 1.00 70.91  ? 161 PRO A CA  1 
ATOM 995   C C   . PRO A 1 161 ? -27.535 -27.414 -17.329 1.00 64.24  ? 161 PRO A C   1 
ATOM 996   O O   . PRO A 1 161 ? -26.713 -28.115 -17.889 1.00 72.59  ? 161 PRO A O   1 
ATOM 997   C CB  . PRO A 1 161 ? -29.800 -28.368 -16.741 1.00 73.15  ? 161 PRO A CB  1 
ATOM 998   C CG  . PRO A 1 161 ? -30.653 -27.209 -16.270 1.00 71.02  ? 161 PRO A CG  1 
ATOM 999   C CD  . PRO A 1 161 ? -30.039 -26.774 -14.957 1.00 60.64  ? 161 PRO A CD  1 
ATOM 1000  N N   . ASP A 1 162 ? -27.758 -26.130 -17.625 1.00 52.41  ? 162 ASP A N   1 
ATOM 1001  C CA  . ASP A 1 162 ? -27.026 -25.441 -18.723 1.00 57.44  ? 162 ASP A CA  1 
ATOM 1002  C C   . ASP A 1 162 ? -25.522 -25.709 -18.608 1.00 58.41  ? 162 ASP A C   1 
ATOM 1003  O O   . ASP A 1 162 ? -24.903 -26.008 -19.648 1.00 65.38  ? 162 ASP A O   1 
ATOM 1004  C CB  . ASP A 1 162 ? -27.323 -23.940 -18.722 1.00 58.91  ? 162 ASP A CB  1 
ATOM 1005  C CG  . ASP A 1 162 ? -28.801 -23.616 -18.864 1.00 72.04  ? 162 ASP A CG  1 
ATOM 1006  O OD1 . ASP A 1 162 ? -29.582 -24.548 -19.146 1.00 77.64  ? 162 ASP A OD1 1 
ATOM 1007  O OD2 . ASP A 1 162 ? -29.160 -22.436 -18.687 1.00 62.08  ? 162 ASP A OD2 1 
ATOM 1008  N N   . PHE A 1 163 ? -24.959 -25.607 -17.400 1.00 57.63  ? 163 PHE A N   1 
ATOM 1009  C CA  . PHE A 1 163 ? -23.498 -25.770 -17.234 1.00 44.04  ? 163 PHE A CA  1 
ATOM 1010  C C   . PHE A 1 163 ? -23.204 -27.261 -17.113 1.00 50.16  ? 163 PHE A C   1 
ATOM 1011  O O   . PHE A 1 163 ? -22.389 -27.777 -17.887 1.00 55.08  ? 163 PHE A O   1 
ATOM 1012  C CB  . PHE A 1 163 ? -23.015 -25.017 -15.995 1.00 45.54  ? 163 PHE A CB  1 
ATOM 1013  C CG  . PHE A 1 163 ? -21.542 -25.157 -15.725 1.00 50.33  ? 163 PHE A CG  1 
ATOM 1014  C CD1 . PHE A 1 163 ? -20.622 -24.457 -16.484 1.00 50.48  ? 163 PHE A CD1 1 
ATOM 1015  C CD2 . PHE A 1 163 ? -21.078 -26.001 -14.730 1.00 40.90  ? 163 PHE A CD2 1 
ATOM 1016  C CE1 . PHE A 1 163 ? -19.266 -24.596 -16.250 1.00 49.38  ? 163 PHE A CE1 1 
ATOM 1017  C CE2 . PHE A 1 163 ? -19.722 -26.147 -14.505 1.00 44.65  ? 163 PHE A CE2 1 
ATOM 1018  C CZ  . PHE A 1 163 ? -18.819 -25.445 -15.267 1.00 52.17  ? 163 PHE A CZ  1 
ATOM 1019  N N   . TYR A 1 164 ? -23.852 -27.932 -16.162 1.00 53.02  ? 164 TYR A N   1 
ATOM 1020  C CA  . TYR A 1 164 ? -23.672 -29.398 -16.038 1.00 56.37  ? 164 TYR A CA  1 
ATOM 1021  C C   . TYR A 1 164 ? -25.029 -30.083 -15.957 1.00 57.39  ? 164 TYR A C   1 
ATOM 1022  O O   . TYR A 1 164 ? -25.800 -29.790 -15.036 1.00 63.45  ? 164 TYR A O   1 
ATOM 1023  C CB  . TYR A 1 164 ? -22.835 -29.760 -14.814 1.00 57.80  ? 164 TYR A CB  1 
ATOM 1024  C CG  . TYR A 1 164 ? -22.640 -31.238 -14.595 1.00 60.69  ? 164 TYR A CG  1 
ATOM 1025  C CD1 . TYR A 1 164 ? -22.117 -32.043 -15.589 1.00 53.02  ? 164 TYR A CD1 1 
ATOM 1026  C CD2 . TYR A 1 164 ? -22.979 -31.830 -13.392 1.00 61.62  ? 164 TYR A CD2 1 
ATOM 1027  C CE1 . TYR A 1 164 ? -21.941 -33.401 -15.399 1.00 55.37  ? 164 TYR A CE1 1 
ATOM 1028  C CE2 . TYR A 1 164 ? -22.805 -33.186 -13.181 1.00 61.09  ? 164 TYR A CE2 1 
ATOM 1029  C CZ  . TYR A 1 164 ? -22.286 -33.976 -14.189 1.00 59.97  ? 164 TYR A CZ  1 
ATOM 1030  O OH  . TYR A 1 164 ? -22.111 -35.313 -13.994 1.00 66.68  ? 164 TYR A OH  1 
ATOM 1031  N N   . ASP A 1 165 ? -25.294 -30.982 -16.898 1.00 56.94  ? 165 ASP A N   1 
ATOM 1032  C CA  . ASP A 1 165 ? -26.561 -31.743 -16.841 1.00 69.46  ? 165 ASP A CA  1 
ATOM 1033  C C   . ASP A 1 165 ? -26.255 -33.121 -16.261 1.00 81.08  ? 165 ASP A C   1 
ATOM 1034  O O   . ASP A 1 165 ? -25.830 -34.004 -17.023 1.00 79.07  ? 165 ASP A O   1 
ATOM 1035  C CB  . ASP A 1 165 ? -27.226 -31.825 -18.211 1.00 73.12  ? 165 ASP A CB  1 
ATOM 1036  C CG  . ASP A 1 165 ? -28.631 -32.404 -18.168 1.00 94.98  ? 165 ASP A CG  1 
ATOM 1037  O OD1 . ASP A 1 165 ? -29.074 -32.787 -17.071 1.00 94.21  ? 165 ASP A OD1 1 
ATOM 1038  O OD2 . ASP A 1 165 ? -29.278 -32.457 -19.233 1.00 103.23 ? 165 ASP A OD2 1 
ATOM 1039  N N   . ASN A 1 166 ? -26.482 -33.283 -14.959 1.00 77.36  ? 166 ASN A N   1 
ATOM 1040  C CA  . ASN A 1 166 ? -26.192 -34.567 -14.279 1.00 79.85  ? 166 ASN A CA  1 
ATOM 1041  C C   . ASN A 1 166 ? -26.977 -35.695 -14.944 1.00 92.18  ? 166 ASN A C   1 
ATOM 1042  O O   . ASN A 1 166 ? -26.341 -36.698 -15.304 1.00 97.24  ? 166 ASN A O   1 
ATOM 1043  C CB  . ASN A 1 166 ? -26.512 -34.475 -12.783 1.00 81.80  ? 166 ASN A CB  1 
ATOM 1044  C CG  . ASN A 1 166 ? -26.261 -35.769 -12.039 1.00 87.25  ? 166 ASN A CG  1 
ATOM 1045  O OD1 . ASN A 1 166 ? -27.182 -36.364 -11.485 1.00 94.51  ? 166 ASN A OD1 1 
ATOM 1046  N ND2 . ASN A 1 166 ? -25.017 -36.218 -12.029 1.00 94.45  ? 166 ASN A ND2 1 
ATOM 1047  N N   . SER A 1 167 ? -28.295 -35.530 -15.124 1.00 97.85  ? 167 SER A N   1 
ATOM 1048  C CA  . SER A 1 167 ? -29.116 -36.660 -15.633 1.00 95.53  ? 167 SER A CA  1 
ATOM 1049  C C   . SER A 1 167 ? -28.294 -37.518 -16.599 1.00 102.17 ? 167 SER A C   1 
ATOM 1050  O O   . SER A 1 167 ? -28.477 -38.750 -16.564 1.00 112.37 ? 167 SER A O   1 
ATOM 1051  C CB  . SER A 1 167 ? -30.372 -36.161 -16.290 1.00 96.13  ? 167 SER A CB  1 
ATOM 1052  O OG  . SER A 1 167 ? -31.245 -37.240 -16.586 1.00 109.26 ? 167 SER A OG  1 
ATOM 1053  N N   . ASN A 1 178 ? -11.805 -45.796 -7.580  1.00 111.03 ? 178 ASN A N   1 
ATOM 1054  C CA  . ASN A 1 178 ? -13.239 -45.901 -7.346  1.00 112.80 ? 178 ASN A CA  1 
ATOM 1055  C C   . ASN A 1 178 ? -13.626 -45.242 -6.028  1.00 115.81 ? 178 ASN A C   1 
ATOM 1056  O O   . ASN A 1 178 ? -14.788 -44.900 -5.806  1.00 119.69 ? 178 ASN A O   1 
ATOM 1057  C CB  . ASN A 1 178 ? -13.678 -47.365 -7.350  1.00 112.81 ? 178 ASN A CB  1 
ATOM 1058  C CG  . ASN A 1 178 ? -12.932 -48.203 -6.328  1.00 110.72 ? 178 ASN A CG  1 
ATOM 1059  O OD1 . ASN A 1 178 ? -13.357 -48.329 -5.181  1.00 113.72 ? 178 ASN A OD1 1 
ATOM 1060  N ND2 . ASN A 1 178 ? -11.809 -48.779 -6.744  1.00 97.04  ? 178 ASN A ND2 1 
ATOM 1061  N N   . MET A 1 179 ? -12.639 -45.061 -5.151  1.00 115.11 ? 179 MET A N   1 
ATOM 1062  C CA  . MET A 1 179 ? -12.878 -44.471 -3.841  1.00 112.68 ? 179 MET A CA  1 
ATOM 1063  C C   . MET A 1 179 ? -11.634 -43.762 -3.325  1.00 106.65 ? 179 MET A C   1 
ATOM 1064  O O   . MET A 1 179 ? -11.728 -42.707 -2.686  1.00 106.28 ? 179 MET A O   1 
ATOM 1065  C CB  . MET A 1 179 ? -13.328 -45.552 -2.853  1.00 118.26 ? 179 MET A CB  1 
ATOM 1066  C CG  . MET A 1 179 ? -13.253 -45.157 -1.378  1.00 117.68 ? 179 MET A CG  1 
ATOM 1067  S SD  . MET A 1 179 ? -14.190 -43.673 -0.953  1.00 119.62 ? 179 MET A SD  1 
ATOM 1068  C CE  . MET A 1 179 ? -15.854 -44.170 -1.388  1.00 115.03 ? 179 MET A CE  1 
ATOM 1069  N N   . LYS A 1 180 ? -10.463 -44.325 -3.613  1.00 110.48 ? 180 LYS A N   1 
ATOM 1070  C CA  . LYS A 1 180 ? -9.219  -43.900 -2.976  1.00 112.03 ? 180 LYS A CA  1 
ATOM 1071  C C   . LYS A 1 180 ? -8.739  -42.566 -3.543  1.00 107.17 ? 180 LYS A C   1 
ATOM 1072  O O   . LYS A 1 180 ? -7.675  -42.060 -3.171  1.00 101.86 ? 180 LYS A O   1 
ATOM 1073  C CB  . LYS A 1 180 ? -8.139  -44.973 -3.144  1.00 111.12 ? 180 LYS A CB  1 
ATOM 1074  C CG  . LYS A 1 180 ? -8.580  -46.370 -2.771  1.00 115.30 ? 180 LYS A CG  1 
ATOM 1075  C CD  . LYS A 1 180 ? -7.505  -47.389 -3.115  1.00 110.59 ? 180 LYS A CD  1 
ATOM 1076  C CE  . LYS A 1 180 ? -8.043  -48.807 -3.030  1.00 115.47 ? 180 LYS A CE  1 
ATOM 1077  N NZ  . LYS A 1 180 ? -9.192  -49.032 -3.946  1.00 112.55 ? 180 LYS A NZ  1 
ATOM 1078  N N   . LEU A 1 181 ? -9.523  -41.998 -4.451  1.00 106.65 ? 181 LEU A N   1 
ATOM 1079  C CA  . LEU A 1 181 ? -9.253  -40.692 -5.027  1.00 97.03  ? 181 LEU A CA  1 
ATOM 1080  C C   . LEU A 1 181 ? -10.339 -39.663 -4.736  1.00 92.28  ? 181 LEU A C   1 
ATOM 1081  O O   . LEU A 1 181 ? -10.023 -38.477 -4.583  1.00 87.85  ? 181 LEU A O   1 
ATOM 1082  C CB  . LEU A 1 181 ? -9.060  -40.820 -6.550  1.00 97.23  ? 181 LEU A CB  1 
ATOM 1083  C CG  . LEU A 1 181 ? -8.265  -39.712 -7.243  1.00 96.18  ? 181 LEU A CG  1 
ATOM 1084  C CD1 . LEU A 1 181 ? -7.511  -40.273 -8.439  1.00 93.83  ? 181 LEU A CD1 1 
ATOM 1085  C CD2 . LEU A 1 181 ? -9.189  -38.591 -7.674  1.00 99.65  ? 181 LEU A CD2 1 
ATOM 1086  N N   . LEU A 1 182 ? -11.605 -40.081 -4.658  1.00 91.26  ? 182 LEU A N   1 
ATOM 1087  C CA  . LEU A 1 182 ? -12.680 -39.150 -4.336  1.00 85.30  ? 182 LEU A CA  1 
ATOM 1088  C C   . LEU A 1 182 ? -12.496 -38.566 -2.941  1.00 77.23  ? 182 LEU A C   1 
ATOM 1089  O O   . LEU A 1 182 ? -12.662 -37.356 -2.734  1.00 68.45  ? 182 LEU A O   1 
ATOM 1090  C CB  . LEU A 1 182 ? -14.031 -39.858 -4.455  1.00 86.80  ? 182 LEU A CB  1 
ATOM 1091  C CG  . LEU A 1 182 ? -15.306 -39.148 -3.996  1.00 79.74  ? 182 LEU A CG  1 
ATOM 1092  C CD1 . LEU A 1 182 ? -15.628 -37.940 -4.869  1.00 88.08  ? 182 LEU A CD1 1 
ATOM 1093  C CD2 . LEU A 1 182 ? -16.469 -40.129 -3.996  1.00 80.61  ? 182 LEU A CD2 1 
ATOM 1094  N N   . HIS A 1 183 ? -12.147 -39.415 -1.972  1.00 85.70  ? 183 HIS A N   1 
ATOM 1095  C CA  . HIS A 1 183 ? -11.886 -38.929 -0.623  1.00 84.88  ? 183 HIS A CA  1 
ATOM 1096  C C   . HIS A 1 183 ? -10.695 -37.978 -0.600  1.00 68.71  ? 183 HIS A C   1 
ATOM 1097  O O   . HIS A 1 183 ? -10.700 -36.985 0.134   1.00 57.20  ? 183 HIS A O   1 
ATOM 1098  C CB  . HIS A 1 183 ? -11.650 -40.100 0.325   1.00 85.20  ? 183 HIS A CB  1 
ATOM 1099  C CG  . HIS A 1 183 ? -11.230 -39.680 1.699   1.00 83.43  ? 183 HIS A CG  1 
ATOM 1100  N ND1 . HIS A 1 183 ? -11.799 -38.613 2.355   1.00 82.09  ? 183 HIS A ND1 1 
ATOM 1101  C CD2 . HIS A 1 183 ? -10.288 -40.179 2.536   1.00 87.25  ? 183 HIS A CD2 1 
ATOM 1102  C CE1 . HIS A 1 183 ? -11.234 -38.474 3.541   1.00 89.07  ? 183 HIS A CE1 1 
ATOM 1103  N NE2 . HIS A 1 183 ? -10.312 -39.411 3.675   1.00 88.15  ? 183 HIS A NE2 1 
ATOM 1104  N N   . ASP A 1 184 ? -9.748  -38.206 -1.496  1.00 63.85  ? 184 ASP A N   1 
ATOM 1105  C CA  . ASP A 1 184 ? -8.531  -37.366 -1.459  1.00 69.54  ? 184 ASP A CA  1 
ATOM 1106  C C   . ASP A 1 184 ? -8.814  -36.027 -2.147  1.00 64.75  ? 184 ASP A C   1 
ATOM 1107  O O   . ASP A 1 184 ? -7.990  -35.126 -2.002  1.00 65.54  ? 184 ASP A O   1 
ATOM 1108  C CB  . ASP A 1 184 ? -7.330  -38.135 -1.999  1.00 79.16  ? 184 ASP A CB  1 
ATOM 1109  C CG  . ASP A 1 184 ? -7.126  -39.453 -1.282  1.00 88.72  ? 184 ASP A CG  1 
ATOM 1110  O OD1 . ASP A 1 184 ? -8.073  -40.256 -1.271  1.00 88.04  ? 184 ASP A OD1 1 
ATOM 1111  O OD2 . ASP A 1 184 ? -6.029  -39.659 -0.736  1.00 91.27  ? 184 ASP A OD2 1 
ATOM 1112  N N   . PHE A 1 185 ? -9.946  -35.898 -2.825  1.00 61.69  ? 185 PHE A N   1 
ATOM 1113  C CA  . PHE A 1 185 ? -10.327 -34.610 -3.447  1.00 51.62  ? 185 PHE A CA  1 
ATOM 1114  C C   . PHE A 1 185 ? -11.050 -33.749 -2.420  1.00 48.68  ? 185 PHE A C   1 
ATOM 1115  O O   . PHE A 1 185 ? -10.823 -32.549 -2.368  1.00 46.76  ? 185 PHE A O   1 
ATOM 1116  C CB  . PHE A 1 185 ? -11.213 -34.896 -4.655  1.00 46.35  ? 185 PHE A CB  1 
ATOM 1117  C CG  . PHE A 1 185 ? -12.090 -33.769 -5.136  1.00 49.51  ? 185 PHE A CG  1 
ATOM 1118  C CD1 . PHE A 1 185 ? -13.309 -33.506 -4.539  1.00 49.01  ? 185 PHE A CD1 1 
ATOM 1119  C CD2 . PHE A 1 185 ? -11.732 -33.014 -6.240  1.00 53.89  ? 185 PHE A CD2 1 
ATOM 1120  C CE1 . PHE A 1 185 ? -14.122 -32.487 -5.002  1.00 48.32  ? 185 PHE A CE1 1 
ATOM 1121  C CE2 . PHE A 1 185 ? -12.545 -31.992 -6.700  1.00 46.21  ? 185 PHE A CE2 1 
ATOM 1122  C CZ  . PHE A 1 185 ? -13.738 -31.730 -6.080  1.00 42.66  ? 185 PHE A CZ  1 
ATOM 1123  N N   . ILE A 1 186 ? -11.894 -34.368 -1.618  1.00 52.21  ? 186 ILE A N   1 
ATOM 1124  C CA  . ILE A 1 186 ? -12.739 -33.623 -0.649  1.00 50.16  ? 186 ILE A CA  1 
ATOM 1125  C C   . ILE A 1 186 ? -11.866 -33.247 0.534   1.00 48.63  ? 186 ILE A C   1 
ATOM 1126  O O   . ILE A 1 186 ? -12.113 -32.217 1.180   1.00 40.81  ? 186 ILE A O   1 
ATOM 1127  C CB  . ILE A 1 186 ? -13.905 -34.537 -0.229  1.00 59.28  ? 186 ILE A CB  1 
ATOM 1128  C CG1 . ILE A 1 186 ? -14.689 -35.043 -1.440  1.00 55.19  ? 186 ILE A CG1 1 
ATOM 1129  C CG2 . ILE A 1 186 ? -14.806 -33.844 0.777   1.00 56.94  ? 186 ILE A CG2 1 
ATOM 1130  C CD1 . ILE A 1 186 ? -14.958 -36.519 -1.390  1.00 59.89  ? 186 ILE A CD1 1 
ATOM 1131  N N   . ALA A 1 187 ? -10.875 -34.084 0.782   1.00 60.08  ? 187 ALA A N   1 
ATOM 1132  C CA  . ALA A 1 187 ? -9.975  -33.846 1.927   1.00 52.58  ? 187 ALA A CA  1 
ATOM 1133  C C   . ALA A 1 187 ? -9.537  -32.393 1.946   1.00 49.54  ? 187 ALA A C   1 
ATOM 1134  O O   . ALA A 1 187 ? -9.748  -31.725 2.952   1.00 48.00  ? 187 ALA A O   1 
ATOM 1135  C CB  . ALA A 1 187 ? -8.786  -34.742 1.788   1.00 49.16  ? 187 ALA A CB  1 
ATOM 1136  N N   . CYS A 1 188 ? -8.941  -31.947 0.854   1.00 41.55  ? 188 CYS A N   1 
ATOM 1137  C CA  . CYS A 1 188 ? -8.409  -30.588 0.909   1.00 48.06  ? 188 CYS A CA  1 
ATOM 1138  C C   . CYS A 1 188 ? -9.499  -29.561 1.178   1.00 45.48  ? 188 CYS A C   1 
ATOM 1139  O O   . CYS A 1 188 ? -9.208  -28.469 1.681   1.00 50.08  ? 188 CYS A O   1 
ATOM 1140  C CB  . CYS A 1 188 ? -7.667  -30.263 -0.386  1.00 54.37  ? 188 CYS A CB  1 
ATOM 1141  S SG  . CYS A 1 188 ? -8.417  -30.974 -1.860  1.00 63.95  ? 188 CYS A SG  1 
ATOM 1142  N N   . PHE A 1 189 ? -10.753 -29.878 0.849   1.00 38.98  ? 189 PHE A N   1 
ATOM 1143  C CA  . PHE A 1 189 ? -11.850 -28.984 1.203   1.00 36.30  ? 189 PHE A CA  1 
ATOM 1144  C C   . PHE A 1 189 ? -12.272 -29.173 2.654   1.00 42.80  ? 189 PHE A C   1 
ATOM 1145  O O   . PHE A 1 189 ? -12.557 -28.194 3.354   1.00 41.14  ? 189 PHE A O   1 
ATOM 1146  C CB  . PHE A 1 189 ? -13.044 -29.212 0.276   1.00 30.79  ? 189 PHE A CB  1 
ATOM 1147  C CG  . PHE A 1 189 ? -12.762 -28.888 -1.160  1.00 31.13  ? 189 PHE A CG  1 
ATOM 1148  C CD1 . PHE A 1 189 ? -12.910 -27.595 -1.632  1.00 26.80  ? 189 PHE A CD1 1 
ATOM 1149  C CD2 . PHE A 1 189 ? -12.349 -29.874 -2.040  1.00 36.37  ? 189 PHE A CD2 1 
ATOM 1150  C CE1 . PHE A 1 189 ? -12.652 -27.292 -2.956  1.00 25.62  ? 189 PHE A CE1 1 
ATOM 1151  C CE2 . PHE A 1 189 ? -12.088 -29.579 -3.361  1.00 30.59  ? 189 PHE A CE2 1 
ATOM 1152  C CZ  . PHE A 1 189 ? -12.239 -28.286 -3.820  1.00 38.10  ? 189 PHE A CZ  1 
ATOM 1153  N N   . GLU A 1 190 ? -12.314 -30.423 3.119   1.00 40.34  ? 190 GLU A N   1 
ATOM 1154  C CA  . GLU A 1 190 ? -12.739 -30.700 4.488   1.00 41.20  ? 190 GLU A CA  1 
ATOM 1155  C C   . GLU A 1 190 ? -11.704 -30.215 5.498   1.00 43.84  ? 190 GLU A C   1 
ATOM 1156  O O   . GLU A 1 190 ? -12.041 -29.515 6.458   1.00 45.74  ? 190 GLU A O   1 
ATOM 1157  C CB  . GLU A 1 190 ? -12.994 -32.197 4.662   1.00 49.60  ? 190 GLU A CB  1 
ATOM 1158  C CG  . GLU A 1 190 ? -13.213 -32.626 6.103   1.00 52.56  ? 190 GLU A CG  1 
ATOM 1159  C CD  . GLU A 1 190 ? -12.812 -34.072 6.349   1.00 64.89  ? 190 GLU A CD  1 
ATOM 1160  O OE1 . GLU A 1 190 ? -12.272 -34.711 5.421   1.00 62.41  ? 190 GLU A OE1 1 
ATOM 1161  O OE2 . GLU A 1 190 ? -13.033 -34.567 7.475   1.00 58.45  ? 190 GLU A OE2 1 
ATOM 1162  N N   . ARG A 1 191 ? -10.436 -30.582 5.297   1.00 44.65  ? 191 ARG A N   1 
ATOM 1163  C CA  . ARG A 1 191 ? -9.400  -30.253 6.269   1.00 39.99  ? 191 ARG A CA  1 
ATOM 1164  C C   . ARG A 1 191 ? -8.998  -28.785 6.247   1.00 36.56  ? 191 ARG A C   1 
ATOM 1165  O O   . ARG A 1 191 ? -8.186  -28.372 7.084   1.00 39.73  ? 191 ARG A O   1 
ATOM 1166  C CB  . ARG A 1 191 ? -8.167  -31.130 6.038   1.00 45.62  ? 191 ARG A CB  1 
ATOM 1167  C CG  . ARG A 1 191 ? -8.260  -32.488 6.704   1.00 47.04  ? 191 ARG A CG  1 
ATOM 1168  C CD  . ARG A 1 191 ? -8.279  -32.345 8.222   1.00 39.51  ? 191 ARG A CD  1 
ATOM 1169  N NE  . ARG A 1 191 ? -8.560  -33.606 8.897   1.00 47.46  ? 191 ARG A NE  1 
ATOM 1170  C CZ  . ARG A 1 191 ? -7.638  -34.495 9.245   1.00 55.09  ? 191 ARG A CZ  1 
ATOM 1171  N NH1 . ARG A 1 191 ? -6.355  -34.300 8.982   1.00 48.50  ? 191 ARG A NH1 1 
ATOM 1172  N NH2 . ARG A 1 191 ? -8.012  -35.605 9.875   1.00 67.25  ? 191 ARG A NH2 1 
ATOM 1173  N N   . SER A 1 192 ? -9.532  -27.990 5.324   1.00 33.52  ? 192 SER A N   1 
ATOM 1174  C CA  . SER A 1 192 ? -9.208  -26.570 5.294   1.00 31.16  ? 192 SER A CA  1 
ATOM 1175  C C   . SER A 1 192 ? -9.833  -25.867 6.494   1.00 28.47  ? 192 SER A C   1 
ATOM 1176  O O   . SER A 1 192 ? -11.017 -26.054 6.787   1.00 33.87  ? 192 SER A O   1 
ATOM 1177  C CB  . SER A 1 192 ? -9.693  -25.944 3.990   1.00 27.30  ? 192 SER A CB  1 
ATOM 1178  O OG  . SER A 1 192 ? -9.305  -24.584 3.905   1.00 26.85  ? 192 SER A OG  1 
ATOM 1179  N N   . CYS A 1 193 ? -9.035  -25.062 7.190   1.00 29.04  ? 193 CYS A N   1 
ATOM 1180  C CA  . CYS A 1 193 ? -9.484  -24.411 8.416   1.00 30.31  ? 193 CYS A CA  1 
ATOM 1181  C C   . CYS A 1 193 ? -10.309 -23.177 8.062   1.00 39.07  ? 193 CYS A C   1 
ATOM 1182  O O   . CYS A 1 193 ? -9.786  -22.213 7.493   1.00 38.12  ? 193 CYS A O   1 
ATOM 1183  C CB  . CYS A 1 193 ? -8.288  -24.043 9.292   1.00 37.66  ? 193 CYS A CB  1 
ATOM 1184  S SG  . CYS A 1 193 ? -8.716  -23.396 10.926  1.00 60.93  ? 193 CYS A SG  1 
ATOM 1185  N N   . ASP A 1 194 ? -11.606 -23.225 8.382   1.00 48.12  ? 194 ASP A N   1 
ATOM 1186  C CA  . ASP A 1 194 ? -12.530 -22.099 8.267   1.00 46.95  ? 194 ASP A CA  1 
ATOM 1187  C C   . ASP A 1 194 ? -12.763 -21.643 6.827   1.00 44.58  ? 194 ASP A C   1 
ATOM 1188  O O   . ASP A 1 194 ? -13.905 -21.652 6.355   1.00 49.35  ? 194 ASP A O   1 
ATOM 1189  C CB  . ASP A 1 194 ? -12.042 -20.920 9.111   1.00 46.99  ? 194 ASP A CB  1 
ATOM 1190  C CG  . ASP A 1 194 ? -11.970 -21.254 10.585  1.00 52.57  ? 194 ASP A CG  1 
ATOM 1191  O OD1 . ASP A 1 194 ? -12.847 -21.995 11.073  1.00 53.20  ? 194 ASP A OD1 1 
ATOM 1192  O OD2 . ASP A 1 194 ? -11.033 -20.774 11.257  1.00 60.44  ? 194 ASP A OD2 1 
ATOM 1193  N N   . ILE A 1 195 ? -11.710 -21.226 6.125   1.00 43.45  ? 195 ILE A N   1 
ATOM 1194  C CA  . ILE A 1 195 ? -11.848 -20.631 4.805   1.00 39.08  ? 195 ILE A CA  1 
ATOM 1195  C C   . ILE A 1 195 ? -11.138 -21.500 3.775   1.00 39.46  ? 195 ILE A C   1 
ATOM 1196  O O   . ILE A 1 195 ? -10.451 -22.464 4.102   1.00 37.75  ? 195 ILE A O   1 
ATOM 1197  C CB  . ILE A 1 195 ? -11.312 -19.185 4.755   1.00 33.63  ? 195 ILE A CB  1 
ATOM 1198  C CG1 . ILE A 1 195 ? -9.784  -19.177 4.836   1.00 28.89  ? 195 ILE A CG1 1 
ATOM 1199  C CG2 . ILE A 1 195 ? -11.923 -18.346 5.869   1.00 36.50  ? 195 ILE A CG2 1 
ATOM 1200  C CD1 . ILE A 1 195 ? -9.164  -17.818 4.581   1.00 31.93  ? 195 ILE A CD1 1 
ATOM 1201  N N   . ILE A 1 196 ? -11.334 -21.141 2.506   1.00 41.95  ? 196 ILE A N   1 
ATOM 1202  C CA  . ILE A 1 196 ? -10.629 -21.742 1.379   1.00 33.57  ? 196 ILE A CA  1 
ATOM 1203  C C   . ILE A 1 196 ? -10.297 -20.628 0.398   1.00 33.12  ? 196 ILE A C   1 
ATOM 1204  O O   . ILE A 1 196 ? -11.204 -19.987 -0.143  1.00 30.21  ? 196 ILE A O   1 
ATOM 1205  C CB  . ILE A 1 196 ? -11.447 -22.838 0.674   1.00 34.71  ? 196 ILE A CB  1 
ATOM 1206  C CG1 . ILE A 1 196 ? -11.613 -24.056 1.579   1.00 34.74  ? 196 ILE A CG1 1 
ATOM 1207  C CG2 . ILE A 1 196 ? -10.777 -23.233 -0.633  1.00 38.05  ? 196 ILE A CG2 1 
ATOM 1208  C CD1 . ILE A 1 196 ? -12.296 -25.221 0.909   1.00 26.97  ? 196 ILE A CD1 1 
ATOM 1209  N N   . LEU A 1 197 ? -9.010  -20.386 0.176   1.00 39.48  ? 197 LEU A N   1 
ATOM 1210  C CA  . LEU A 1 197 ? -8.584  -19.393 -0.796  1.00 36.82  ? 197 LEU A CA  1 
ATOM 1211  C C   . LEU A 1 197 ? -8.723  -19.948 -2.208  1.00 31.27  ? 197 LEU A C   1 
ATOM 1212  O O   . LEU A 1 197 ? -8.439  -21.122 -2.459  1.00 28.73  ? 197 LEU A O   1 
ATOM 1213  C CB  . LEU A 1 197 ? -7.136  -18.977 -0.535  1.00 38.77  ? 197 LEU A CB  1 
ATOM 1214  C CG  . LEU A 1 197 ? -6.861  -18.218 0.764   1.00 38.89  ? 197 LEU A CG  1 
ATOM 1215  C CD1 . LEU A 1 197 ? -5.372  -17.979 0.934   1.00 37.07  ? 197 LEU A CD1 1 
ATOM 1216  C CD2 . LEU A 1 197 ? -7.616  -16.903 0.765   1.00 39.87  ? 197 LEU A CD2 1 
ATOM 1217  N N   . ILE A 1 198 ? -9.166  -19.100 -3.133  1.00 30.55  ? 198 ILE A N   1 
ATOM 1218  C CA  . ILE A 1 198 ? -9.382  -19.526 -4.511  1.00 32.94  ? 198 ILE A CA  1 
ATOM 1219  C C   . ILE A 1 198 ? -8.851  -18.461 -5.462  1.00 33.17  ? 198 ILE A C   1 
ATOM 1220  O O   . ILE A 1 198 ? -9.064  -17.263 -5.257  1.00 34.60  ? 198 ILE A O   1 
ATOM 1221  C CB  . ILE A 1 198 ? -10.871 -19.829 -4.792  1.00 38.18  ? 198 ILE A CB  1 
ATOM 1222  C CG1 . ILE A 1 198 ? -11.073 -20.204 -6.264  1.00 33.78  ? 198 ILE A CG1 1 
ATOM 1223  C CG2 . ILE A 1 198 ? -11.752 -18.661 -4.389  1.00 33.48  ? 198 ILE A CG2 1 
ATOM 1224  C CD1 . ILE A 1 198 ? -12.509 -20.508 -6.631  1.00 32.59  ? 198 ILE A CD1 1 
ATOM 1225  N N   . LYS A 1 199 ? -8.139  -18.911 -6.498  1.00 40.78  ? 199 LYS A N   1 
ATOM 1226  C CA  . LYS A 1 199 ? -7.676  -18.048 -7.585  1.00 36.96  ? 199 LYS A CA  1 
ATOM 1227  C C   . LYS A 1 199 ? -8.834  -17.849 -8.555  1.00 34.57  ? 199 LYS A C   1 
ATOM 1228  O O   . LYS A 1 199 ? -8.936  -18.485 -9.609  1.00 32.10  ? 199 LYS A O   1 
ATOM 1229  C CB  . LYS A 1 199 ? -6.459  -18.649 -8.278  1.00 36.72  ? 199 LYS A CB  1 
ATOM 1230  C CG  . LYS A 1 199 ? -5.903  -17.800 -9.409  1.00 36.16  ? 199 LYS A CG  1 
ATOM 1231  C CD  . LYS A 1 199 ? -4.848  -18.557 -10.200 1.00 30.31  ? 199 LYS A CD  1 
ATOM 1232  C CE  . LYS A 1 199 ? -4.385  -17.765 -11.414 1.00 34.06  ? 199 LYS A CE  1 
ATOM 1233  N NZ  . LYS A 1 199 ? -3.438  -18.555 -12.243 1.00 58.69  ? 199 LYS A NZ  1 
ATOM 1234  N N   . SER A 1 200 ? -9.734  -16.950 -8.179  1.00 31.25  ? 200 SER A N   1 
ATOM 1235  C CA  . SER A 1 200 ? -10.896 -16.632 -8.996  1.00 36.11  ? 200 SER A CA  1 
ATOM 1236  C C   . SER A 1 200 ? -11.436 -15.289 -8.530  1.00 30.76  ? 200 SER A C   1 
ATOM 1237  O O   . SER A 1 200 ? -10.918 -14.683 -7.590  1.00 37.51  ? 200 SER A O   1 
ATOM 1238  C CB  . SER A 1 200 ? -11.952 -17.739 -8.906  1.00 32.00  ? 200 SER A CB  1 
ATOM 1239  O OG  . SER A 1 200 ? -13.039 -17.486 -9.781  1.00 35.88  ? 200 SER A OG  1 
ATOM 1240  N N   . PHE A 1 201 ? -12.481 -14.821 -9.203  1.00 28.04  ? 201 PHE A N   1 
ATOM 1241  C CA  . PHE A 1 201 ? -13.087 -13.540 -8.879  1.00 37.79  ? 201 PHE A CA  1 
ATOM 1242  C C   . PHE A 1 201 ? -14.591 -13.639 -9.073  1.00 42.82  ? 201 PHE A C   1 
ATOM 1243  O O   . PHE A 1 201 ? -15.076 -14.384 -9.930  1.00 34.38  ? 201 PHE A O   1 
ATOM 1244  C CB  . PHE A 1 201 ? -12.502 -12.397 -9.725  1.00 35.69  ? 201 PHE A CB  1 
ATOM 1245  C CG  . PHE A 1 201 ? -12.070 -12.810 -11.107 1.00 38.60  ? 201 PHE A CG  1 
ATOM 1246  C CD1 . PHE A 1 201 ? -10.818 -13.372 -11.316 1.00 32.56  ? 201 PHE A CD1 1 
ATOM 1247  C CD2 . PHE A 1 201 ? -12.901 -12.616 -12.194 1.00 45.10  ? 201 PHE A CD2 1 
ATOM 1248  C CE1 . PHE A 1 201 ? -10.415 -13.751 -12.584 1.00 37.89  ? 201 PHE A CE1 1 
ATOM 1249  C CE2 . PHE A 1 201 ? -12.498 -12.986 -13.466 1.00 43.20  ? 201 PHE A CE2 1 
ATOM 1250  C CZ  . PHE A 1 201 ? -11.256 -13.558 -13.658 1.00 48.01  ? 201 PHE A CZ  1 
ATOM 1251  N N   . ARG A 1 202 ? -15.327 -12.878 -8.258  1.00 35.45  ? 202 ARG A N   1 
ATOM 1252  C CA  . ARG A 1 202 ? -16.781 -12.987 -8.242  1.00 39.12  ? 202 ARG A CA  1 
ATOM 1253  C C   . ARG A 1 202 ? -17.393 -12.589 -9.579  1.00 49.52  ? 202 ARG A C   1 
ATOM 1254  O O   . ARG A 1 202 ? -18.410 -13.161 -9.985  1.00 40.44  ? 202 ARG A O   1 
ATOM 1255  C CB  . ARG A 1 202 ? -17.353 -12.134 -7.110  1.00 37.14  ? 202 ARG A CB  1 
ATOM 1256  C CG  . ARG A 1 202 ? -18.750 -12.525 -6.662  1.00 48.09  ? 202 ARG A CG  1 
ATOM 1257  C CD  . ARG A 1 202 ? -18.855 -12.495 -5.146  1.00 42.34  ? 202 ARG A CD  1 
ATOM 1258  N NE  . ARG A 1 202 ? -18.041 -13.532 -4.524  1.00 56.31  ? 202 ARG A NE  1 
ATOM 1259  C CZ  . ARG A 1 202 ? -17.740 -13.577 -3.230  1.00 61.29  ? 202 ARG A CZ  1 
ATOM 1260  N NH1 . ARG A 1 202 ? -18.154 -12.639 -2.392  1.00 68.57  ? 202 ARG A NH1 1 
ATOM 1261  N NH2 . ARG A 1 202 ? -17.005 -14.585 -2.770  1.00 49.63  ? 202 ARG A NH2 1 
ATOM 1262  N N   . GLU A 1 203 ? -16.778 -11.639 -10.288 1.00 50.40  ? 203 GLU A N   1 
ATOM 1263  C CA  . GLU A 1 203 ? -17.342 -11.146 -11.540 1.00 47.09  ? 203 GLU A CA  1 
ATOM 1264  C C   . GLU A 1 203 ? -17.446 -12.228 -12.608 1.00 51.54  ? 203 GLU A C   1 
ATOM 1265  O O   . GLU A 1 203 ? -18.187 -12.051 -13.578 1.00 57.69  ? 203 GLU A O   1 
ATOM 1266  C CB  . GLU A 1 203 ? -16.497 -9.988  -12.070 1.00 43.26  ? 203 GLU A CB  1 
ATOM 1267  C CG  . GLU A 1 203 ? -16.079 -8.998  -11.001 1.00 48.39  ? 203 GLU A CG  1 
ATOM 1268  C CD  . GLU A 1 203 ? -17.267 -8.319  -10.346 1.00 69.13  ? 203 GLU A CD  1 
ATOM 1269  O OE1 . GLU A 1 203 ? -18.245 -8.009  -11.061 1.00 61.65  ? 203 GLU A OE1 1 
ATOM 1270  O OE2 . GLU A 1 203 ? -17.221 -8.101  -9.116  1.00 74.09  ? 203 GLU A OE2 1 
ATOM 1271  N N   . LEU A 1 204 ? -16.720 -13.335 -12.460 1.00 47.27  ? 204 LEU A N   1 
ATOM 1272  C CA  . LEU A 1 204 ? -16.745 -14.408 -13.448 1.00 44.01  ? 204 LEU A CA  1 
ATOM 1273  C C   . LEU A 1 204 ? -17.577 -15.608 -13.017 1.00 53.22  ? 204 LEU A C   1 
ATOM 1274  O O   . LEU A 1 204 ? -18.220 -16.237 -13.863 1.00 55.78  ? 204 LEU A O   1 
ATOM 1275  C CB  . LEU A 1 204 ? -15.319 -14.872 -13.764 1.00 36.97  ? 204 LEU A CB  1 
ATOM 1276  C CG  . LEU A 1 204 ? -15.141 -15.986 -14.797 1.00 41.43  ? 204 LEU A CG  1 
ATOM 1277  C CD1 . LEU A 1 204 ? -15.858 -15.656 -16.098 1.00 45.70  ? 204 LEU A CD1 1 
ATOM 1278  C CD2 . LEU A 1 204 ? -13.660 -16.244 -15.054 1.00 46.33  ? 204 LEU A CD2 1 
ATOM 1279  N N   . GLU A 1 205 ? -17.594 -15.937 -11.730 1.00 43.89  ? 205 GLU A N   1 
ATOM 1280  C CA  . GLU A 1 205 ? -18.283 -17.135 -11.265 1.00 46.44  ? 205 GLU A CA  1 
ATOM 1281  C C   . GLU A 1 205 ? -18.683 -16.979 -9.801  1.00 42.67  ? 205 GLU A C   1 
ATOM 1282  O O   . GLU A 1 205 ? -18.439 -17.857 -8.973  1.00 43.87  ? 205 GLU A O   1 
ATOM 1283  C CB  . GLU A 1 205 ? -17.414 -18.376 -11.472 1.00 48.53  ? 205 GLU A CB  1 
ATOM 1284  C CG  . GLU A 1 205 ? -16.003 -18.255 -10.899 1.00 40.39  ? 205 GLU A CG  1 
ATOM 1285  C CD  . GLU A 1 205 ? -15.302 -19.597 -10.750 1.00 45.97  ? 205 GLU A CD  1 
ATOM 1286  O OE1 . GLU A 1 205 ? -15.965 -20.644 -10.901 1.00 48.89  ? 205 GLU A OE1 1 
ATOM 1287  O OE2 . GLU A 1 205 ? -14.082 -19.603 -10.474 1.00 50.41  ? 205 GLU A OE2 1 
ATOM 1288  N N   . GLY A 1 206 ? -19.308 -15.851 -9.459  1.00 34.78  ? 206 GLY A N   1 
ATOM 1289  C CA  . GLY A 1 206 ? -19.773 -15.673 -8.093  1.00 31.15  ? 206 GLY A CA  1 
ATOM 1290  C C   . GLY A 1 206 ? -20.815 -16.703 -7.703  1.00 40.11  ? 206 GLY A C   1 
ATOM 1291  O O   . GLY A 1 206 ? -20.842 -17.173 -6.561  1.00 37.25  ? 206 GLY A O   1 
ATOM 1292  N N   . LYS A 1 207 ? -21.673 -17.077 -8.653  1.00 47.89  ? 207 LYS A N   1 
ATOM 1293  C CA  . LYS A 1 207 ? -22.670 -18.115 -8.405  1.00 42.50  ? 207 LYS A CA  1 
ATOM 1294  C C   . LYS A 1 207 ? -22.006 -19.429 -8.008  1.00 39.51  ? 207 LYS A C   1 
ATOM 1295  O O   . LYS A 1 207 ? -22.358 -20.037 -6.987  1.00 36.15  ? 207 LYS A O   1 
ATOM 1296  C CB  . LYS A 1 207 ? -23.538 -18.293 -9.653  1.00 27.74  ? 207 LYS A CB  1 
ATOM 1297  C CG  . LYS A 1 207 ? -24.417 -19.527 -9.658  1.00 49.67  ? 207 LYS A CG  1 
ATOM 1298  C CD  . LYS A 1 207 ? -25.299 -19.553 -10.903 1.00 52.87  ? 207 LYS A CD  1 
ATOM 1299  C CE  . LYS A 1 207 ? -24.471 -19.410 -12.175 1.00 46.73  ? 207 LYS A CE  1 
ATOM 1300  N NZ  . LYS A 1 207 ? -25.328 -19.319 -13.393 1.00 43.22  ? 207 LYS A NZ  1 
ATOM 1301  N N   . TYR A 1 208 ? -21.025 -19.873 -8.792  1.00 41.11  ? 208 TYR A N   1 
ATOM 1302  C CA  . TYR A 1 208 ? -20.361 -21.136 -8.493  1.00 45.65  ? 208 TYR A CA  1 
ATOM 1303  C C   . TYR A 1 208 ? -19.488 -21.032 -7.250  1.00 45.75  ? 208 TYR A C   1 
ATOM 1304  O O   . TYR A 1 208 ? -19.314 -22.026 -6.538  1.00 44.45  ? 208 TYR A O   1 
ATOM 1305  C CB  . TYR A 1 208 ? -19.544 -21.589 -9.702  1.00 46.09  ? 208 TYR A CB  1 
ATOM 1306  C CG  . TYR A 1 208 ? -20.367 -21.688 -10.966 1.00 46.08  ? 208 TYR A CG  1 
ATOM 1307  C CD1 . TYR A 1 208 ? -21.108 -22.828 -11.247 1.00 47.19  ? 208 TYR A CD1 1 
ATOM 1308  C CD2 . TYR A 1 208 ? -20.414 -20.638 -11.871 1.00 52.68  ? 208 TYR A CD2 1 
ATOM 1309  C CE1 . TYR A 1 208 ? -21.865 -22.922 -12.397 1.00 50.53  ? 208 TYR A CE1 1 
ATOM 1310  C CE2 . TYR A 1 208 ? -21.170 -20.719 -13.022 1.00 50.28  ? 208 TYR A CE2 1 
ATOM 1311  C CZ  . TYR A 1 208 ? -21.895 -21.863 -13.282 1.00 48.74  ? 208 TYR A CZ  1 
ATOM 1312  O OH  . TYR A 1 208 ? -22.651 -21.951 -14.430 1.00 52.24  ? 208 TYR A OH  1 
ATOM 1313  N N   . ILE A 1 209 ? -18.952 -19.847 -6.955  1.00 46.00  ? 209 ILE A N   1 
ATOM 1314  C CA  . ILE A 1 209 ? -18.172 -19.681 -5.732  1.00 44.89  ? 209 ILE A CA  1 
ATOM 1315  C C   . ILE A 1 209 ? -19.071 -19.810 -4.509  1.00 44.45  ? 209 ILE A C   1 
ATOM 1316  O O   . ILE A 1 209 ? -18.707 -20.457 -3.520  1.00 44.02  ? 209 ILE A O   1 
ATOM 1317  C CB  . ILE A 1 209 ? -17.420 -18.338 -5.752  1.00 46.62  ? 209 ILE A CB  1 
ATOM 1318  C CG1 . ILE A 1 209 ? -16.223 -18.415 -6.699  1.00 43.19  ? 209 ILE A CG1 1 
ATOM 1319  C CG2 . ILE A 1 209 ? -16.955 -17.954 -4.356  1.00 55.85  ? 209 ILE A CG2 1 
ATOM 1320  C CD1 . ILE A 1 209 ? -15.428 -17.133 -6.783  1.00 41.22  ? 209 ILE A CD1 1 
ATOM 1321  N N   . ASP A 1 210 ? -20.259 -19.208 -4.554  1.00 49.94  ? 210 ASP A N   1 
ATOM 1322  C CA  . ASP A 1 210 ? -21.212 -19.375 -3.461  1.00 49.02  ? 210 ASP A CA  1 
ATOM 1323  C C   . ASP A 1 210 ? -21.660 -20.828 -3.338  1.00 47.37  ? 210 ASP A C   1 
ATOM 1324  O O   . ASP A 1 210 ? -21.807 -21.349 -2.222  1.00 40.57  ? 210 ASP A O   1 
ATOM 1325  C CB  . ASP A 1 210 ? -22.412 -18.452 -3.670  1.00 37.06  ? 210 ASP A CB  1 
ATOM 1326  C CG  . ASP A 1 210 ? -22.025 -16.984 -3.648  1.00 46.49  ? 210 ASP A CG  1 
ATOM 1327  O OD1 . ASP A 1 210 ? -21.083 -16.634 -2.902  1.00 57.24  ? 210 ASP A OD1 1 
ATOM 1328  O OD2 . ASP A 1 210 ? -22.654 -16.183 -4.375  1.00 49.22  ? 210 ASP A OD2 1 
ATOM 1329  N N   . LEU A 1 211 ? -21.886 -21.495 -4.475  1.00 43.39  ? 211 LEU A N   1 
ATOM 1330  C CA  . LEU A 1 211 ? -22.222 -22.914 -4.431  1.00 43.23  ? 211 LEU A CA  1 
ATOM 1331  C C   . LEU A 1 211 ? -21.126 -23.717 -3.743  1.00 45.93  ? 211 LEU A C   1 
ATOM 1332  O O   . LEU A 1 211 ? -21.410 -24.561 -2.886  1.00 48.19  ? 211 LEU A O   1 
ATOM 1333  C CB  . LEU A 1 211 ? -22.470 -23.446 -5.841  1.00 51.54  ? 211 LEU A CB  1 
ATOM 1334  C CG  . LEU A 1 211 ? -22.746 -24.947 -5.957  1.00 48.42  ? 211 LEU A CG  1 
ATOM 1335  C CD1 . LEU A 1 211 ? -23.965 -25.340 -5.139  1.00 39.50  ? 211 LEU A CD1 1 
ATOM 1336  C CD2 . LEU A 1 211 ? -22.919 -25.346 -7.412  1.00 43.22  ? 211 LEU A CD2 1 
ATOM 1337  N N   . LEU A 1 212 ? -19.866 -23.457 -4.104  1.00 48.78  ? 212 LEU A N   1 
ATOM 1338  C CA  . LEU A 1 212 ? -18.743 -24.163 -3.492  1.00 46.74  ? 212 LEU A CA  1 
ATOM 1339  C C   . LEU A 1 212 ? -18.641 -23.855 -2.003  1.00 46.65  ? 212 LEU A C   1 
ATOM 1340  O O   . LEU A 1 212 ? -18.311 -24.736 -1.199  1.00 43.96  ? 212 LEU A O   1 
ATOM 1341  C CB  . LEU A 1 212 ? -17.449 -23.784 -4.207  1.00 44.80  ? 212 LEU A CB  1 
ATOM 1342  C CG  . LEU A 1 212 ? -16.218 -24.665 -3.998  1.00 53.23  ? 212 LEU A CG  1 
ATOM 1343  C CD1 . LEU A 1 212 ? -16.438 -26.026 -4.631  1.00 48.62  ? 212 LEU A CD1 1 
ATOM 1344  C CD2 . LEU A 1 212 ? -14.975 -23.998 -4.571  1.00 44.42  ? 212 LEU A CD2 1 
ATOM 1345  N N   . SER A 1 213 ? -18.913 -22.603 -1.622  1.00 46.58  ? 213 SER A N   1 
ATOM 1346  C CA  . SER A 1 213 ? -18.949 -22.230 -0.210  1.00 44.47  ? 213 SER A CA  1 
ATOM 1347  C C   . SER A 1 213 ? -19.953 -23.081 0.552   1.00 46.22  ? 213 SER A C   1 
ATOM 1348  O O   . SER A 1 213 ? -19.635 -23.646 1.605   1.00 54.72  ? 213 SER A O   1 
ATOM 1349  C CB  . SER A 1 213 ? -19.302 -20.750 -0.058  1.00 44.44  ? 213 SER A CB  1 
ATOM 1350  O OG  . SER A 1 213 ? -18.288 -19.911 -0.573  1.00 48.46  ? 213 SER A OG  1 
ATOM 1351  N N   . THR A 1 214 ? -21.180 -23.174 0.040   1.00 41.83  ? 214 THR A N   1 
ATOM 1352  C CA  . THR A 1 214 ? -22.188 -23.946 0.751   1.00 41.57  ? 214 THR A CA  1 
ATOM 1353  C C   . THR A 1 214 ? -21.873 -25.435 0.736   1.00 41.52  ? 214 THR A C   1 
ATOM 1354  O O   . THR A 1 214 ? -22.129 -26.132 1.726   1.00 43.38  ? 214 THR A O   1 
ATOM 1355  C CB  . THR A 1 214 ? -23.576 -23.694 0.163   1.00 43.50  ? 214 THR A CB  1 
ATOM 1356  O OG1 . THR A 1 214 ? -23.622 -24.181 -1.183  1.00 48.73  ? 214 THR A OG1 1 
ATOM 1357  C CG2 . THR A 1 214 ? -23.895 -22.208 0.180   1.00 37.79  ? 214 THR A CG2 1 
ATOM 1358  N N   . LEU A 1 215 ? -21.304 -25.942 -0.357  1.00 47.47  ? 215 LEU A N   1 
ATOM 1359  C CA  . LEU A 1 215 ? -21.041 -27.373 -0.449  1.00 51.78  ? 215 LEU A CA  1 
ATOM 1360  C C   . LEU A 1 215 ? -19.899 -27.790 0.470   1.00 50.73  ? 215 LEU A C   1 
ATOM 1361  O O   . LEU A 1 215 ? -19.936 -28.875 1.058   1.00 52.94  ? 215 LEU A O   1 
ATOM 1362  C CB  . LEU A 1 215 ? -20.738 -27.764 -1.897  1.00 49.26  ? 215 LEU A CB  1 
ATOM 1363  C CG  . LEU A 1 215 ? -21.941 -27.798 -2.844  1.00 42.29  ? 215 LEU A CG  1 
ATOM 1364  C CD1 . LEU A 1 215 ? -21.489 -28.071 -4.263  1.00 47.83  ? 215 LEU A CD1 1 
ATOM 1365  C CD2 . LEU A 1 215 ? -22.960 -28.838 -2.390  1.00 43.97  ? 215 LEU A CD2 1 
ATOM 1366  N N   . SER A 1 216 ? -18.879 -26.944 0.615   1.00 44.08  ? 216 SER A N   1 
ATOM 1367  C CA  . SER A 1 216 ? -17.734 -27.284 1.445   1.00 38.83  ? 216 SER A CA  1 
ATOM 1368  C C   . SER A 1 216 ? -17.921 -26.916 2.911   1.00 50.68  ? 216 SER A C   1 
ATOM 1369  O O   . SER A 1 216 ? -17.124 -27.362 3.745   1.00 51.17  ? 216 SER A O   1 
ATOM 1370  C CB  . SER A 1 216 ? -16.473 -26.599 0.913   1.00 44.70  ? 216 SER A CB  1 
ATOM 1371  O OG  . SER A 1 216 ? -16.598 -25.189 0.957   1.00 35.10  ? 216 SER A OG  1 
ATOM 1372  N N   . ASP A 1 217 ? -18.953 -26.137 3.242   1.00 48.58  ? 217 ASP A N   1 
ATOM 1373  C CA  . ASP A 1 217 ? -19.130 -25.533 4.562   1.00 45.65  ? 217 ASP A CA  1 
ATOM 1374  C C   . ASP A 1 217 ? -17.956 -24.640 4.945   1.00 45.89  ? 217 ASP A C   1 
ATOM 1375  O O   . ASP A 1 217 ? -17.692 -24.424 6.132   1.00 61.10  ? 217 ASP A O   1 
ATOM 1376  C CB  . ASP A 1 217 ? -19.367 -26.594 5.647   1.00 57.12  ? 217 ASP A CB  1 
ATOM 1377  C CG  . ASP A 1 217 ? -20.679 -27.331 5.463   1.00 58.38  ? 217 ASP A CG  1 
ATOM 1378  O OD1 . ASP A 1 217 ? -21.358 -27.088 4.443   1.00 61.94  ? 217 ASP A OD1 1 
ATOM 1379  O OD2 . ASP A 1 217 ? -21.033 -28.148 6.342   1.00 60.17  ? 217 ASP A OD2 1 
ATOM 1380  N N   . LYS A 1 218 ? -17.238 -24.114 3.958   1.00 44.43  ? 218 LYS A N   1 
ATOM 1381  C CA  . LYS A 1 218 ? -16.132 -23.200 4.186   1.00 50.52  ? 218 LYS A CA  1 
ATOM 1382  C C   . LYS A 1 218 ? -16.395 -21.894 3.451   1.00 46.45  ? 218 LYS A C   1 
ATOM 1383  O O   . LYS A 1 218 ? -17.119 -21.860 2.454   1.00 54.55  ? 218 LYS A O   1 
ATOM 1384  C CB  . LYS A 1 218 ? -14.794 -23.795 3.719   1.00 42.24  ? 218 LYS A CB  1 
ATOM 1385  C CG  . LYS A 1 218 ? -14.052 -24.608 4.775   1.00 42.91  ? 218 LYS A CG  1 
ATOM 1386  C CD  . LYS A 1 218 ? -14.797 -25.879 5.131   1.00 42.91  ? 218 LYS A CD  1 
ATOM 1387  C CE  . LYS A 1 218 ? -13.979 -26.758 6.049   1.00 35.34  ? 218 LYS A CE  1 
ATOM 1388  N NZ  . LYS A 1 218 ? -13.552 -25.998 7.248   1.00 42.66  ? 218 LYS A NZ  1 
ATOM 1389  N N   . THR A 1 219 ? -15.806 -20.817 3.954   1.00 41.81  ? 219 THR A N   1 
ATOM 1390  C CA  . THR A 1 219 ? -15.946 -19.523 3.307   1.00 42.86  ? 219 THR A CA  1 
ATOM 1391  C C   . THR A 1 219 ? -14.933 -19.431 2.174   1.00 41.16  ? 219 THR A C   1 
ATOM 1392  O O   . THR A 1 219 ? -13.720 -19.481 2.408   1.00 41.64  ? 219 THR A O   1 
ATOM 1393  C CB  . THR A 1 219 ? -15.759 -18.387 4.313   1.00 49.95  ? 219 THR A CB  1 
ATOM 1394  O OG1 . THR A 1 219 ? -16.673 -18.565 5.402   1.00 43.45  ? 219 THR A OG1 1 
ATOM 1395  C CG2 . THR A 1 219 ? -16.039 -17.045 3.652   1.00 41.95  ? 219 THR A CG2 1 
ATOM 1396  N N   . LEU A 1 220 ? -15.426 -19.342 0.944   1.00 37.86  ? 220 LEU A N   1 
ATOM 1397  C CA  . LEU A 1 220 ? -14.555 -19.192 -0.210  1.00 39.20  ? 220 LEU A CA  1 
ATOM 1398  C C   . LEU A 1 220 ? -14.068 -17.752 -0.272  1.00 37.06  ? 220 LEU A C   1 
ATOM 1399  O O   . LEU A 1 220 ? -14.874 -16.822 -0.386  1.00 42.40  ? 220 LEU A O   1 
ATOM 1400  C CB  . LEU A 1 220 ? -15.284 -19.578 -1.494  1.00 39.18  ? 220 LEU A CB  1 
ATOM 1401  C CG  . LEU A 1 220 ? -15.053 -20.996 -2.019  1.00 40.26  ? 220 LEU A CG  1 
ATOM 1402  C CD1 . LEU A 1 220 ? -13.612 -21.169 -2.471  1.00 37.73  ? 220 LEU A CD1 1 
ATOM 1403  C CD2 . LEU A 1 220 ? -15.411 -22.038 -0.972  1.00 39.58  ? 220 LEU A CD2 1 
ATOM 1404  N N   . VAL A 1 221 ? -12.759 -17.567 -0.177  1.00 33.84  ? 221 VAL A N   1 
ATOM 1405  C CA  . VAL A 1 221 ? -12.150 -16.245 -0.238  1.00 37.74  ? 221 VAL A CA  1 
ATOM 1406  C C   . VAL A 1 221 ? -11.434 -16.129 -1.581  1.00 34.78  ? 221 VAL A C   1 
ATOM 1407  O O   . VAL A 1 221 ? -10.426 -16.817 -1.814  1.00 39.16  ? 221 VAL A O   1 
ATOM 1408  C CB  . VAL A 1 221 ? -11.193 -16.005 0.936   1.00 36.10  ? 221 VAL A CB  1 
ATOM 1409  C CG1 . VAL A 1 221 ? -10.733 -14.565 0.941   1.00 38.48  ? 221 VAL A CG1 1 
ATOM 1410  C CG2 . VAL A 1 221 ? -11.879 -16.349 2.247   1.00 35.23  ? 221 VAL A CG2 1 
ATOM 1411  N N   . PRO A 1 222 ? -11.934 -15.316 -2.505  1.00 35.36  ? 222 PRO A N   1 
ATOM 1412  C CA  . PRO A 1 222 ? -11.260 -15.157 -3.795  1.00 39.56  ? 222 PRO A CA  1 
ATOM 1413  C C   . PRO A 1 222 ? -10.136 -14.138 -3.716  1.00 39.13  ? 222 PRO A C   1 
ATOM 1414  O O   . PRO A 1 222 ? -10.276 -13.068 -3.117  1.00 44.82  ? 222 PRO A O   1 
ATOM 1415  C CB  . PRO A 1 222 ? -12.386 -14.672 -4.717  1.00 41.85  ? 222 PRO A CB  1 
ATOM 1416  C CG  . PRO A 1 222 ? -13.310 -13.933 -3.800  1.00 48.48  ? 222 PRO A CG  1 
ATOM 1417  C CD  . PRO A 1 222 ? -13.247 -14.647 -2.475  1.00 39.49  ? 222 PRO A CD  1 
ATOM 1418  N N   . VAL A 1 223 ? -9.008  -14.484 -4.328  1.00 36.15  ? 223 VAL A N   1 
ATOM 1419  C CA  . VAL A 1 223 ? -7.851  -13.605 -4.394  1.00 34.03  ? 223 VAL A CA  1 
ATOM 1420  C C   . VAL A 1 223 ? -7.687  -13.013 -5.791  1.00 41.42  ? 223 VAL A C   1 
ATOM 1421  O O   . VAL A 1 223 ? -6.616  -12.510 -6.131  1.00 42.29  ? 223 VAL A O   1 
ATOM 1422  C CB  . VAL A 1 223 ? -6.570  -14.330 -3.944  1.00 34.68  ? 223 VAL A CB  1 
ATOM 1423  C CG1 . VAL A 1 223 ? -6.689  -14.765 -2.489  1.00 44.65  ? 223 VAL A CG1 1 
ATOM 1424  C CG2 . VAL A 1 223 ? -6.297  -15.517 -4.846  1.00 31.36  ? 223 VAL A CG2 1 
ATOM 1425  N N   . GLY A 1 224 ? -8.736  -13.069 -6.609  1.00 41.14  ? 224 GLY A N   1 
ATOM 1426  C CA  . GLY A 1 224 ? -8.701  -12.513 -7.940  1.00 38.94  ? 224 GLY A CA  1 
ATOM 1427  C C   . GLY A 1 224 ? -7.722  -13.239 -8.836  1.00 34.11  ? 224 GLY A C   1 
ATOM 1428  O O   . GLY A 1 224 ? -7.273  -14.350 -8.538  1.00 39.09  ? 224 GLY A O   1 
ATOM 1429  N N   . PRO A 1 225 ? -7.384  -12.631 -9.966  1.00 30.85  ? 225 PRO A N   1 
ATOM 1430  C CA  . PRO A 1 225 ? -6.345  -13.196 -10.827 1.00 39.31  ? 225 PRO A CA  1 
ATOM 1431  C C   . PRO A 1 225 ? -4.961  -12.798 -10.340 1.00 49.38  ? 225 PRO A C   1 
ATOM 1432  O O   . PRO A 1 225 ? -4.785  -11.857 -9.562  1.00 55.73  ? 225 PRO A O   1 
ATOM 1433  C CB  . PRO A 1 225 ? -6.650  -12.575 -12.190 1.00 30.61  ? 225 PRO A CB  1 
ATOM 1434  C CG  . PRO A 1 225 ? -7.185  -11.231 -11.838 1.00 34.64  ? 225 PRO A CG  1 
ATOM 1435  C CD  . PRO A 1 225 ? -7.970  -11.411 -10.550 1.00 36.72  ? 225 PRO A CD  1 
ATOM 1436  N N   . LEU A 1 226 ? -3.966  -13.539 -10.818 1.00 43.01  ? 226 LEU A N   1 
ATOM 1437  C CA  . LEU A 1 226 ? -2.570  -13.303 -10.469 1.00 42.16  ? 226 LEU A CA  1 
ATOM 1438  C C   . LEU A 1 226 ? -1.781  -13.186 -11.766 1.00 51.92  ? 226 LEU A C   1 
ATOM 1439  O O   . LEU A 1 226 ? -1.560  -14.191 -12.448 1.00 53.04  ? 226 LEU A O   1 
ATOM 1440  C CB  . LEU A 1 226 ? -2.033  -14.425 -9.584  1.00 46.49  ? 226 LEU A CB  1 
ATOM 1441  C CG  . LEU A 1 226 ? -2.779  -14.607 -8.258  1.00 39.25  ? 226 LEU A CG  1 
ATOM 1442  C CD1 . LEU A 1 226 ? -2.868  -16.078 -7.881  1.00 31.08  ? 226 LEU A CD1 1 
ATOM 1443  C CD2 . LEU A 1 226 ? -2.099  -13.812 -7.150  1.00 52.33  ? 226 LEU A CD2 1 
ATOM 1444  N N   . VAL A 1 227 ? -1.358  -11.961 -12.086 1.00 61.75  ? 227 VAL A N   1 
ATOM 1445  C CA  . VAL A 1 227 ? -0.749  -11.588 -13.369 1.00 55.99  ? 227 VAL A CA  1 
ATOM 1446  C C   . VAL A 1 227 ? -1.429  -12.288 -14.539 1.00 55.04  ? 227 VAL A C   1 
ATOM 1447  O O   . VAL A 1 227 ? -2.628  -12.116 -14.756 1.00 56.59  ? 227 VAL A O   1 
ATOM 1448  C CB  . VAL A 1 227 ? 0.781   -11.853 -13.382 1.00 56.32  ? 227 VAL A CB  1 
ATOM 1449  C CG1 . VAL A 1 227 ? 1.430   -11.319 -12.114 1.00 60.07  ? 227 VAL A CG1 1 
ATOM 1450  C CG2 . VAL A 1 227 ? 1.108   -13.330 -13.604 1.00 45.99  ? 227 VAL A CG2 1 
ATOM 1451  N N   . ASP A 1 236 ? 15.065  -14.280 -24.598 1.00 134.71 ? 236 ASP A N   1 
ATOM 1452  C CA  . ASP A 1 236 ? 14.448  -13.054 -24.097 1.00 140.11 ? 236 ASP A CA  1 
ATOM 1453  C C   . ASP A 1 236 ? 14.715  -11.825 -24.981 1.00 134.67 ? 236 ASP A C   1 
ATOM 1454  O O   . ASP A 1 236 ? 13.856  -10.952 -25.079 1.00 128.11 ? 236 ASP A O   1 
ATOM 1455  C CB  . ASP A 1 236 ? 14.904  -12.782 -22.660 1.00 147.35 ? 236 ASP A CB  1 
ATOM 1456  C CG  . ASP A 1 236 ? 14.333  -13.780 -21.674 1.00 154.17 ? 236 ASP A CG  1 
ATOM 1457  O OD1 . ASP A 1 236 ? 13.287  -14.390 -21.984 1.00 153.70 ? 236 ASP A OD1 1 
ATOM 1458  O OD2 . ASP A 1 236 ? 14.925  -13.952 -20.587 1.00 153.70 ? 236 ASP A OD2 1 
ATOM 1459  N N   . PRO A 1 237 ? 15.890  -11.732 -25.615 1.00 134.51 ? 237 PRO A N   1 
ATOM 1460  C CA  . PRO A 1 237 ? 16.040  -10.763 -26.714 1.00 124.72 ? 237 PRO A CA  1 
ATOM 1461  C C   . PRO A 1 237 ? 15.265  -11.135 -27.969 1.00 117.38 ? 237 PRO A C   1 
ATOM 1462  O O   . PRO A 1 237 ? 15.362  -10.418 -28.971 1.00 111.64 ? 237 PRO A O   1 
ATOM 1463  C CB  . PRO A 1 237 ? 17.553  -10.764 -26.982 1.00 123.17 ? 237 PRO A CB  1 
ATOM 1464  C CG  . PRO A 1 237 ? 18.157  -11.204 -25.706 1.00 128.36 ? 237 PRO A CG  1 
ATOM 1465  C CD  . PRO A 1 237 ? 17.206  -12.223 -25.160 1.00 133.60 ? 237 PRO A CD  1 
ATOM 1466  N N   . LYS A 1 238 ? 14.503  -12.226 -27.949 1.00 116.32 ? 238 LYS A N   1 
ATOM 1467  C CA  . LYS A 1 238 ? 13.735  -12.682 -29.097 1.00 104.39 ? 238 LYS A CA  1 
ATOM 1468  C C   . LYS A 1 238 ? 12.314  -12.130 -29.123 1.00 98.48  ? 238 LYS A C   1 
ATOM 1469  O O   . LYS A 1 238 ? 11.558  -12.453 -30.047 1.00 98.77  ? 238 LYS A O   1 
ATOM 1470  C CB  . LYS A 1 238 ? 13.684  -14.215 -29.120 1.00 107.11 ? 238 LYS A CB  1 
ATOM 1471  C CG  . LYS A 1 238 ? 12.991  -14.823 -27.908 1.00 104.24 ? 238 LYS A CG  1 
ATOM 1472  C CD  . LYS A 1 238 ? 12.886  -16.337 -28.016 1.00 90.29  ? 238 LYS A CD  1 
ATOM 1473  C CE  . LYS A 1 238 ? 12.083  -16.909 -26.855 1.00 89.87  ? 238 LYS A CE  1 
ATOM 1474  N NZ  . LYS A 1 238 ? 11.906  -18.384 -26.962 1.00 90.45  ? 238 LYS A NZ  1 
ATOM 1475  N N   . THR A 1 239 ? 11.931  -11.317 -28.141 1.00 101.71 ? 239 THR A N   1 
ATOM 1476  C CA  . THR A 1 239 ? 10.571  -10.798 -28.052 1.00 92.57  ? 239 THR A CA  1 
ATOM 1477  C C   . THR A 1 239 ? 10.430  -9.376  -28.578 1.00 92.19  ? 239 THR A C   1 
ATOM 1478  O O   . THR A 1 239 ? 9.304   -8.874  -28.657 1.00 86.88  ? 239 THR A O   1 
ATOM 1479  C CB  . THR A 1 239 ? 10.075  -10.835 -26.602 1.00 86.57  ? 239 THR A CB  1 
ATOM 1480  O OG1 . THR A 1 239 ? 8.746   -10.309 -26.545 1.00 84.28  ? 239 THR A OG1 1 
ATOM 1481  C CG2 . THR A 1 239 ? 10.968  -9.992  -25.715 1.00 101.43 ? 239 THR A CG2 1 
ATOM 1482  N N   . GLU A 1 240 ? 11.536  -8.713  -28.923 1.00 98.93  ? 240 GLU A N   1 
ATOM 1483  C CA  . GLU A 1 240 ? 11.450  -7.347  -29.428 1.00 90.58  ? 240 GLU A CA  1 
ATOM 1484  C C   . GLU A 1 240 ? 10.711  -7.304  -30.762 1.00 80.21  ? 240 GLU A C   1 
ATOM 1485  O O   . GLU A 1 240 ? 9.934   -6.378  -31.019 1.00 70.60  ? 240 GLU A O   1 
ATOM 1486  C CB  . GLU A 1 240 ? 12.851  -6.755  -29.563 1.00 100.50 ? 240 GLU A CB  1 
ATOM 1487  C CG  . GLU A 1 240 ? 13.848  -7.322  -28.557 1.00 97.11  ? 240 GLU A CG  1 
ATOM 1488  C CD  . GLU A 1 240 ? 15.210  -6.650  -28.624 1.00 87.91  ? 240 GLU A CD  1 
ATOM 1489  O OE1 . GLU A 1 240 ? 15.285  -5.488  -29.072 1.00 91.62  ? 240 GLU A OE1 1 
ATOM 1490  O OE2 . GLU A 1 240 ? 16.207  -7.289  -28.227 1.00 82.64  ? 240 GLU A OE2 1 
ATOM 1491  N N   . GLN A 1 241 ? 10.943  -8.305  -31.618 1.00 86.46  ? 241 GLN A N   1 
ATOM 1492  C CA  . GLN A 1 241 ? 10.206  -8.396  -32.874 1.00 90.55  ? 241 GLN A CA  1 
ATOM 1493  C C   . GLN A 1 241 ? 8.704   -8.468  -32.626 1.00 86.81  ? 241 GLN A C   1 
ATOM 1494  O O   . GLN A 1 241 ? 7.920   -7.858  -33.362 1.00 90.05  ? 241 GLN A O   1 
ATOM 1495  C CB  . GLN A 1 241 ? 10.677  -9.611  -33.676 1.00 94.26  ? 241 GLN A CB  1 
ATOM 1496  C CG  . GLN A 1 241 ? 12.005  -9.426  -34.407 1.00 102.61 ? 241 GLN A CG  1 
ATOM 1497  C CD  . GLN A 1 241 ? 13.218  -9.637  -33.518 1.00 105.07 ? 241 GLN A CD  1 
ATOM 1498  O OE1 . GLN A 1 241 ? 13.268  -10.572 -32.721 1.00 101.19 ? 241 GLN A OE1 1 
ATOM 1499  N NE2 . GLN A 1 241 ? 14.207  -8.764  -33.660 1.00 105.84 ? 241 GLN A NE2 1 
ATOM 1500  N N   . ILE A 1 242 ? 8.287   -9.193  -31.585 1.00 80.72  ? 242 ILE A N   1 
ATOM 1501  C CA  . ILE A 1 242 ? 6.863   -9.342  -31.284 1.00 73.55  ? 242 ILE A CA  1 
ATOM 1502  C C   . ILE A 1 242 ? 6.223   -7.982  -31.034 1.00 71.14  ? 242 ILE A C   1 
ATOM 1503  O O   . ILE A 1 242 ? 5.226   -7.617  -31.668 1.00 66.15  ? 242 ILE A O   1 
ATOM 1504  C CB  . ILE A 1 242 ? 6.667   -10.281 -30.079 1.00 83.84  ? 242 ILE A CB  1 
ATOM 1505  C CG1 . ILE A 1 242 ? 7.312   -11.640 -30.347 1.00 78.08  ? 242 ILE A CG1 1 
ATOM 1506  C CG2 . ILE A 1 242 ? 5.188   -10.440 -29.762 1.00 72.75  ? 242 ILE A CG2 1 
ATOM 1507  C CD1 . ILE A 1 242 ? 6.668   -12.407 -31.475 1.00 79.93  ? 242 ILE A CD1 1 
ATOM 1508  N N   . ILE A 1 243 ? 6.781   -7.212  -30.096 1.00 75.78  ? 243 ILE A N   1 
ATOM 1509  C CA  . ILE A 1 243 ? 6.185   -5.925  -29.746 1.00 75.38  ? 243 ILE A CA  1 
ATOM 1510  C C   . ILE A 1 243 ? 6.316   -4.939  -30.902 1.00 75.29  ? 243 ILE A C   1 
ATOM 1511  O O   . ILE A 1 243 ? 5.407   -4.137  -31.153 1.00 73.79  ? 243 ILE A O   1 
ATOM 1512  C CB  . ILE A 1 243 ? 6.814   -5.376  -28.452 1.00 80.82  ? 243 ILE A CB  1 
ATOM 1513  C CG1 . ILE A 1 243 ? 6.500   -6.303  -27.275 1.00 83.31  ? 243 ILE A CG1 1 
ATOM 1514  C CG2 . ILE A 1 243 ? 6.305   -3.974  -28.157 1.00 76.90  ? 243 ILE A CG2 1 
ATOM 1515  C CD1 . ILE A 1 243 ? 5.016   -6.465  -27.000 1.00 72.43  ? 243 ILE A CD1 1 
ATOM 1516  N N   . ASN A 1 244 ? 7.437   -4.981  -31.627 1.00 77.70  ? 244 ASN A N   1 
ATOM 1517  C CA  . ASN A 1 244 ? 7.595   -4.077  -32.763 1.00 76.29  ? 244 ASN A CA  1 
ATOM 1518  C C   . ASN A 1 244 ? 6.556   -4.364  -33.840 1.00 72.37  ? 244 ASN A C   1 
ATOM 1519  O O   . ASN A 1 244 ? 6.023   -3.436  -34.462 1.00 73.12  ? 244 ASN A O   1 
ATOM 1520  C CB  . ASN A 1 244 ? 9.009   -4.186  -33.337 1.00 74.39  ? 244 ASN A CB  1 
ATOM 1521  C CG  . ASN A 1 244 ? 9.274   -3.154  -34.417 1.00 79.10  ? 244 ASN A CG  1 
ATOM 1522  O OD1 . ASN A 1 244 ? 8.637   -2.101  -34.454 1.00 80.25  ? 244 ASN A OD1 1 
ATOM 1523  N ND2 . ASN A 1 244 ? 10.215  -3.452  -35.306 1.00 73.02  ? 244 ASN A ND2 1 
ATOM 1524  N N   . TRP A 1 245 ? 6.084   -5.607  -33.922 1.00 69.99  ? 245 TRP A N   1 
ATOM 1525  C CA  . TRP A 1 245 ? 5.037   -5.969  -34.915 1.00 68.64  ? 245 TRP A CA  1 
ATOM 1526  C C   . TRP A 1 245 ? 3.655   -5.523  -34.444 1.00 69.84  ? 245 TRP A C   1 
ATOM 1527  O O   . TRP A 1 245 ? 2.913   -5.002  -35.269 1.00 60.49  ? 245 TRP A O   1 
ATOM 1528  C CB  . TRP A 1 245 ? 5.069   -7.477  -35.159 1.00 63.35  ? 245 TRP A CB  1 
ATOM 1529  C CG  . TRP A 1 245 ? 4.151   -7.987  -36.228 1.00 71.41  ? 245 TRP A CG  1 
ATOM 1530  C CD1 . TRP A 1 245 ? 4.487   -8.284  -37.516 1.00 77.67  ? 245 TRP A CD1 1 
ATOM 1531  C CD2 . TRP A 1 245 ? 2.760   -8.328  -36.092 1.00 79.02  ? 245 TRP A CD2 1 
ATOM 1532  N NE1 . TRP A 1 245 ? 3.398   -8.748  -38.199 1.00 72.50  ? 245 TRP A NE1 1 
ATOM 1533  C CE2 . TRP A 1 245 ? 2.324   -8.790  -37.353 1.00 74.64  ? 245 TRP A CE2 1 
ATOM 1534  C CE3 . TRP A 1 245 ? 1.838   -8.272  -35.044 1.00 65.93  ? 245 TRP A CE3 1 
ATOM 1535  C CZ2 . TRP A 1 245 ? 1.014   -9.194  -37.585 1.00 71.87  ? 245 TRP A CZ2 1 
ATOM 1536  C CZ3 . TRP A 1 245 ? 0.542   -8.669  -35.275 1.00 62.65  ? 245 TRP A CZ3 1 
ATOM 1537  C CH2 . TRP A 1 245 ? 0.138   -9.120  -36.530 1.00 71.52  ? 245 TRP A CH2 1 
ATOM 1538  N N   . LEU A 1 246 ? 3.334   -5.726  -33.169 1.00 69.99  ? 246 LEU A N   1 
ATOM 1539  C CA  . LEU A 1 246 ? 1.975   -5.442  -32.639 1.00 63.16  ? 246 LEU A CA  1 
ATOM 1540  C C   . LEU A 1 246 ? 1.746   -3.941  -32.529 1.00 63.49  ? 246 LEU A C   1 
ATOM 1541  O O   . LEU A 1 246 ? 0.592   -3.530  -32.613 1.00 64.51  ? 246 LEU A O   1 
ATOM 1542  C CB  . LEU A 1 246 ? 1.857   -6.121  -31.273 1.00 62.17  ? 246 LEU A CB  1 
ATOM 1543  C CG  . LEU A 1 246 ? 0.449   -6.435  -30.782 1.00 61.76  ? 246 LEU A CG  1 
ATOM 1544  C CD1 . LEU A 1 246 ? -0.249  -7.378  -31.742 1.00 65.85  ? 246 LEU A CD1 1 
ATOM 1545  C CD2 . LEU A 1 246 ? 0.505   -7.055  -29.399 1.00 56.82  ? 246 LEU A CD2 1 
ATOM 1546  N N   . ASP A 1 247 ? 2.803   -3.172  -32.349 1.00 62.83  ? 247 ASP A N   1 
ATOM 1547  C CA  . ASP A 1 247 ? 2.617   -1.721  -32.126 1.00 68.60  ? 247 ASP A CA  1 
ATOM 1548  C C   . ASP A 1 247 ? 2.245   -1.044  -33.439 1.00 70.32  ? 247 ASP A C   1 
ATOM 1549  O O   . ASP A 1 247 ? 1.561   -0.017  -33.385 1.00 69.79  ? 247 ASP A O   1 
ATOM 1550  C CB  . ASP A 1 247 ? 3.861   -1.088  -31.509 1.00 69.84  ? 247 ASP A CB  1 
ATOM 1551  C CG  . ASP A 1 247 ? 4.315   -1.747  -30.222 1.00 75.18  ? 247 ASP A CG  1 
ATOM 1552  O OD1 . ASP A 1 247 ? 3.704   -2.760  -29.845 1.00 76.73  ? 247 ASP A OD1 1 
ATOM 1553  O OD2 . ASP A 1 247 ? 5.266   -1.237  -29.604 1.00 69.39  ? 247 ASP A OD2 1 
ATOM 1554  N N   . LYS A 1 248 ? 2.652   -1.624  -34.564 1.00 70.45  ? 248 LYS A N   1 
ATOM 1555  C CA  . LYS A 1 248 ? 2.417   -0.981  -35.877 1.00 67.55  ? 248 LYS A CA  1 
ATOM 1556  C C   . LYS A 1 248 ? 1.082   -1.435  -36.461 1.00 69.56  ? 248 LYS A C   1 
ATOM 1557  O O   . LYS A 1 248 ? 0.896   -1.293  -37.676 1.00 75.02  ? 248 LYS A O   1 
ATOM 1558  C CB  . LYS A 1 248 ? 3.594   -1.290  -36.798 1.00 73.01  ? 248 LYS A CB  1 
ATOM 1559  C CG  . LYS A 1 248 ? 4.023   -0.139  -37.697 1.00 83.32  ? 248 LYS A CG  1 
ATOM 1560  C CD  . LYS A 1 248 ? 3.999   1.197   -36.991 1.00 86.03  ? 248 LYS A CD  1 
ATOM 1561  C CE  . LYS A 1 248 ? 4.872   2.239   -37.654 1.00 89.45  ? 248 LYS A CE  1 
ATOM 1562  N NZ  . LYS A 1 248 ? 6.307   1.885   -37.562 1.00 93.56  ? 248 LYS A NZ  1 
ATOM 1563  N N   . ARG A 1 249 ? 0.187   -1.947  -35.619 1.00 71.89  ? 249 ARG A N   1 
ATOM 1564  C CA  . ARG A 1 249 ? -1.151  -2.395  -36.063 1.00 62.60  ? 249 ARG A CA  1 
ATOM 1565  C C   . ARG A 1 249 ? -2.173  -1.624  -35.255 1.00 57.43  ? 249 ARG A C   1 
ATOM 1566  O O   . ARG A 1 249 ? -1.844  -1.191  -34.146 1.00 58.41  ? 249 ARG A O   1 
ATOM 1567  C CB  . ARG A 1 249 ? -1.328  -3.887  -35.799 1.00 61.40  ? 249 ARG A CB  1 
ATOM 1568  C CG  . ARG A 1 249 ? -0.045  -4.704  -35.849 1.00 65.47  ? 249 ARG A CG  1 
ATOM 1569  C CD  . ARG A 1 249 ? 0.528   -4.911  -37.237 1.00 61.36  ? 249 ARG A CD  1 
ATOM 1570  N NE  . ARG A 1 249 ? -0.244  -5.867  -38.008 1.00 63.71  ? 249 ARG A NE  1 
ATOM 1571  C CZ  . ARG A 1 249 ? -0.940  -5.559  -39.093 1.00 71.80  ? 249 ARG A CZ  1 
ATOM 1572  N NH1 . ARG A 1 249 ? -1.133  -4.295  -39.413 1.00 72.35  ? 249 ARG A NH1 1 
ATOM 1573  N NH2 . ARG A 1 249 ? -1.454  -6.514  -39.846 1.00 71.89  ? 249 ARG A NH2 1 
ATOM 1574  N N   . ALA A 1 250 ? -3.381  -1.505  -35.770 1.00 58.03  ? 250 ALA A N   1 
ATOM 1575  C CA  . ALA A 1 250 ? -4.377  -0.647  -35.091 1.00 67.05  ? 250 ALA A CA  1 
ATOM 1576  C C   . ALA A 1 250 ? -4.888  -1.253  -33.784 1.00 65.67  ? 250 ALA A C   1 
ATOM 1577  O O   . ALA A 1 250 ? -4.508  -2.370  -33.450 1.00 62.12  ? 250 ALA A O   1 
ATOM 1578  C CB  . ALA A 1 250 ? -5.507  -0.345  -36.034 1.00 59.54  ? 250 ALA A CB  1 
ATOM 1579  N N   . GLU A 1 251 ? -5.758  -0.520  -33.098 1.00 63.06  ? 251 GLU A N   1 
ATOM 1580  C CA  . GLU A 1 251 ? -6.213  -0.949  -31.783 1.00 66.19  ? 251 GLU A CA  1 
ATOM 1581  C C   . GLU A 1 251 ? -7.291  -2.019  -31.907 1.00 69.48  ? 251 GLU A C   1 
ATOM 1582  O O   . GLU A 1 251 ? -8.211  -1.899  -32.723 1.00 67.84  ? 251 GLU A O   1 
ATOM 1583  C CB  . GLU A 1 251 ? -6.752  0.244   -30.991 1.00 69.09  ? 251 GLU A CB  1 
ATOM 1584  C CG  . GLU A 1 251 ? -5.804  0.768   -29.920 1.00 71.22  ? 251 GLU A CG  1 
ATOM 1585  C CD  . GLU A 1 251 ? -6.470  1.758   -28.978 1.00 82.60  ? 251 GLU A CD  1 
ATOM 1586  O OE1 . GLU A 1 251 ? -7.676  2.027   -29.154 1.00 70.68  ? 251 GLU A OE1 1 
ATOM 1587  O OE2 . GLU A 1 251 ? -5.788  2.264   -28.063 1.00 87.43  ? 251 GLU A OE2 1 
ATOM 1588  N N   . SER A 1 252 ? -7.167  -3.070  -31.095 1.00 63.64  ? 252 SER A N   1 
ATOM 1589  C CA  . SER A 1 252 ? -8.172  -4.129  -30.993 1.00 63.90  ? 252 SER A CA  1 
ATOM 1590  C C   . SER A 1 252 ? -8.441  -4.791  -32.345 1.00 59.90  ? 252 SER A C   1 
ATOM 1591  O O   . SER A 1 252 ? -9.578  -5.137  -32.672 1.00 59.70  ? 252 SER A O   1 
ATOM 1592  C CB  . SER A 1 252 ? -9.469  -3.595  -30.381 1.00 64.85  ? 252 SER A CB  1 
ATOM 1593  O OG  . SER A 1 252 ? -9.228  -3.005  -29.116 1.00 65.68  ? 252 SER A OG  1 
ATOM 1594  N N   . THR A 1 253 ? -7.384  -4.969  -33.136 1.00 58.28  ? 253 THR A N   1 
ATOM 1595  C CA  . THR A 1 253 ? -7.491  -5.631  -34.426 1.00 54.25  ? 253 THR A CA  1 
ATOM 1596  C C   . THR A 1 253 ? -6.686  -6.920  -34.518 1.00 61.35  ? 253 THR A C   1 
ATOM 1597  O O   . THR A 1 253 ? -6.850  -7.658  -35.496 1.00 67.35  ? 253 THR A O   1 
ATOM 1598  C CB  . THR A 1 253 ? -7.045  -4.691  -35.558 1.00 60.06  ? 253 THR A CB  1 
ATOM 1599  O OG1 . THR A 1 253 ? -5.682  -4.299  -35.347 1.00 60.56  ? 253 THR A OG1 1 
ATOM 1600  C CG2 . THR A 1 253 ? -7.922  -3.450  -35.597 1.00 57.24  ? 253 THR A CG2 1 
ATOM 1601  N N   . VAL A 1 254 ? -5.831  -7.209  -33.542 1.00 56.51  ? 254 VAL A N   1 
ATOM 1602  C CA  . VAL A 1 254 ? -4.988  -8.398  -33.549 1.00 58.79  ? 254 VAL A CA  1 
ATOM 1603  C C   . VAL A 1 254 ? -5.635  -9.468  -32.682 1.00 59.65  ? 254 VAL A C   1 
ATOM 1604  O O   . VAL A 1 254 ? -6.141  -9.181  -31.590 1.00 57.77  ? 254 VAL A O   1 
ATOM 1605  C CB  . VAL A 1 254 ? -3.565  -8.076  -33.056 1.00 63.47  ? 254 VAL A CB  1 
ATOM 1606  C CG1 . VAL A 1 254 ? -2.648  -9.275  -33.247 1.00 58.71  ? 254 VAL A CG1 1 
ATOM 1607  C CG2 . VAL A 1 254 ? -3.019  -6.853  -33.775 1.00 67.04  ? 254 VAL A CG2 1 
ATOM 1608  N N   . VAL A 1 255 ? -5.619  -10.705 -33.169 1.00 56.54  ? 255 VAL A N   1 
ATOM 1609  C CA  . VAL A 1 255 ? -6.143  -11.854 -32.444 1.00 55.96  ? 255 VAL A CA  1 
ATOM 1610  C C   . VAL A 1 255 ? -4.959  -12.713 -32.024 1.00 58.27  ? 255 VAL A C   1 
ATOM 1611  O O   . VAL A 1 255 ? -4.181  -13.171 -32.869 1.00 56.25  ? 255 VAL A O   1 
ATOM 1612  C CB  . VAL A 1 255 ? -7.139  -12.656 -33.297 1.00 53.07  ? 255 VAL A CB  1 
ATOM 1613  C CG1 . VAL A 1 255 ? -7.734  -13.797 -32.490 1.00 53.01  ? 255 VAL A CG1 1 
ATOM 1614  C CG2 . VAL A 1 255 ? -8.233  -11.743 -33.824 1.00 60.08  ? 255 VAL A CG2 1 
ATOM 1615  N N   . PHE A 1 256 ? -4.809  -12.913 -30.720 1.00 59.90  ? 256 PHE A N   1 
ATOM 1616  C CA  . PHE A 1 256 ? -3.739  -13.742 -30.185 1.00 57.59  ? 256 PHE A CA  1 
ATOM 1617  C C   . PHE A 1 256 ? -4.218  -15.182 -30.077 1.00 60.30  ? 256 PHE A C   1 
ATOM 1618  O O   . PHE A 1 256 ? -5.256  -15.457 -29.469 1.00 63.76  ? 256 PHE A O   1 
ATOM 1619  C CB  . PHE A 1 256 ? -3.282  -13.226 -28.821 1.00 57.26  ? 256 PHE A CB  1 
ATOM 1620  C CG  . PHE A 1 256 ? -2.200  -14.054 -28.192 1.00 56.38  ? 256 PHE A CG  1 
ATOM 1621  C CD1 . PHE A 1 256 ? -0.922  -14.065 -28.726 1.00 55.47  ? 256 PHE A CD1 1 
ATOM 1622  C CD2 . PHE A 1 256 ? -2.457  -14.817 -27.067 1.00 58.01  ? 256 PHE A CD2 1 
ATOM 1623  C CE1 . PHE A 1 256 ? 0.077   -14.825 -28.153 1.00 53.12  ? 256 PHE A CE1 1 
ATOM 1624  C CE2 . PHE A 1 256 ? -1.459  -15.582 -26.488 1.00 66.30  ? 256 PHE A CE2 1 
ATOM 1625  C CZ  . PHE A 1 256 ? -0.191  -15.584 -27.030 1.00 70.36  ? 256 PHE A CZ  1 
ATOM 1626  N N   . VAL A 1 257 ? -3.468  -16.097 -30.685 1.00 65.93  ? 257 VAL A N   1 
ATOM 1627  C CA  . VAL A 1 257 ? -3.811  -17.510 -30.723 1.00 56.13  ? 257 VAL A CA  1 
ATOM 1628  C C   . VAL A 1 257 ? -2.720  -18.275 -29.997 1.00 68.90  ? 257 VAL A C   1 
ATOM 1629  O O   . VAL A 1 257 ? -1.530  -18.087 -30.274 1.00 75.40  ? 257 VAL A O   1 
ATOM 1630  C CB  . VAL A 1 257 ? -3.971  -18.022 -32.166 1.00 53.87  ? 257 VAL A CB  1 
ATOM 1631  C CG1 . VAL A 1 257 ? -4.486  -19.459 -32.162 1.00 60.19  ? 257 VAL A CG1 1 
ATOM 1632  C CG2 . VAL A 1 257 ? -4.907  -17.110 -32.943 1.00 56.51  ? 257 VAL A CG2 1 
ATOM 1633  N N   . CYS A 1 258 ? -3.131  -19.093 -29.019 1.00 66.03  ? 258 CYS A N   1 
ATOM 1634  C CA  . CYS A 1 258 ? -2.174  -19.968 -28.296 1.00 60.48  ? 258 CYS A CA  1 
ATOM 1635  C C   . CYS A 1 258 ? -2.940  -21.102 -27.625 1.00 63.47  ? 258 CYS A C   1 
ATOM 1636  O O   . CYS A 1 258 ? -4.007  -20.836 -27.081 1.00 70.85  ? 258 CYS A O   1 
ATOM 1637  C CB  . CYS A 1 258 ? -1.384  -19.215 -27.242 1.00 68.12  ? 258 CYS A CB  1 
ATOM 1638  S SG  . CYS A 1 258 ? -0.001  -20.178 -26.583 1.00 91.95  ? 258 CYS A SG  1 
ATOM 1639  N N   . PHE A 1 259 ? -2.410  -22.325 -27.687 1.00 68.00  ? 259 PHE A N   1 
ATOM 1640  C CA  . PHE A 1 259 ? -3.065  -23.481 -27.019 1.00 65.53  ? 259 PHE A CA  1 
ATOM 1641  C C   . PHE A 1 259 ? -2.150  -23.985 -25.902 1.00 62.06  ? 259 PHE A C   1 
ATOM 1642  O O   . PHE A 1 259 ? -2.006  -25.211 -25.751 1.00 70.86  ? 259 PHE A O   1 
ATOM 1643  C CB  . PHE A 1 259 ? -3.464  -24.536 -28.054 1.00 73.44  ? 259 PHE A CB  1 
ATOM 1644  C CG  . PHE A 1 259 ? -4.360  -23.993 -29.138 1.00 67.19  ? 259 PHE A CG  1 
ATOM 1645  C CD1 . PHE A 1 259 ? -5.633  -23.533 -28.841 1.00 66.39  ? 259 PHE A CD1 1 
ATOM 1646  C CD2 . PHE A 1 259 ? -3.919  -23.907 -30.450 1.00 64.35  ? 259 PHE A CD2 1 
ATOM 1647  C CE1 . PHE A 1 259 ? -6.452  -23.019 -29.833 1.00 69.64  ? 259 PHE A CE1 1 
ATOM 1648  C CE2 . PHE A 1 259 ? -4.741  -23.396 -31.442 1.00 59.45  ? 259 PHE A CE2 1 
ATOM 1649  C CZ  . PHE A 1 259 ? -6.005  -22.953 -31.132 1.00 50.12  ? 259 PHE A CZ  1 
ATOM 1650  N N   . GLY A 1 260 ? -1.547  -23.056 -25.152 1.00 79.32  ? 260 GLY A N   1 
ATOM 1651  C CA  . GLY A 1 260 ? -0.649  -23.428 -24.042 1.00 78.44  ? 260 GLY A CA  1 
ATOM 1652  C C   . GLY A 1 260 ? 0.453   -24.368 -24.491 1.00 80.26  ? 260 GLY A C   1 
ATOM 1653  O O   . GLY A 1 260 ? 1.106   -24.068 -25.511 1.00 75.45  ? 260 GLY A O   1 
ATOM 1654  N N   . SER A 1 261 ? 0.637   -25.483 -23.778 1.00 84.12  ? 261 SER A N   1 
ATOM 1655  C CA  . SER A 1 261 ? 1.650   -26.498 -24.171 1.00 89.91  ? 261 SER A CA  1 
ATOM 1656  C C   . SER A 1 261 ? 1.051   -27.893 -23.979 1.00 93.02  ? 261 SER A C   1 
ATOM 1657  O O   . SER A 1 261 ? 1.817   -28.875 -24.030 1.00 84.46  ? 261 SER A O   1 
ATOM 1658  C CB  . SER A 1 261 ? 2.913   -26.334 -23.370 1.00 78.40  ? 261 SER A CB  1 
ATOM 1659  O OG  . SER A 1 261 ? 2.655   -26.517 -21.986 1.00 85.96  ? 261 SER A OG  1 
ATOM 1660  N N   . GLU A 1 262 ? -0.266  -27.967 -23.766 1.00 98.61  ? 262 GLU A N   1 
ATOM 1661  C CA  . GLU A 1 262 ? -0.934  -29.271 -23.513 1.00 102.68 ? 262 GLU A CA  1 
ATOM 1662  C C   . GLU A 1 262 ? -0.811  -30.167 -24.750 1.00 108.81 ? 262 GLU A C   1 
ATOM 1663  O O   . GLU A 1 262 ? -0.363  -31.320 -24.596 1.00 106.83 ? 262 GLU A O   1 
ATOM 1664  C CB  . GLU A 1 262 ? -2.401  -29.046 -23.148 1.00 99.35  ? 262 GLU A CB  1 
ATOM 1665  C CG  . GLU A 1 262 ? -2.594  -28.344 -21.817 1.00 107.67 ? 262 GLU A CG  1 
ATOM 1666  C CD  . GLU A 1 262 ? -4.036  -28.036 -21.447 1.00 104.49 ? 262 GLU A CD  1 
ATOM 1667  O OE1 . GLU A 1 262 ? -4.915  -28.196 -22.313 1.00 98.74  ? 262 GLU A OE1 1 
ATOM 1668  O OE2 . GLU A 1 262 ? -4.277  -27.644 -20.290 1.00 112.94 ? 262 GLU A OE2 1 
ATOM 1669  N N   . TYR A 1 263 ? -1.193  -29.655 -25.925 1.00 112.64 ? 263 TYR A N   1 
ATOM 1670  C CA  . TYR A 1 263 ? -1.164  -30.470 -27.160 1.00 112.52 ? 263 TYR A CA  1 
ATOM 1671  C C   . TYR A 1 263 ? -0.689  -29.613 -28.335 1.00 113.71 ? 263 TYR A C   1 
ATOM 1672  O O   . TYR A 1 263 ? -1.337  -28.583 -28.612 1.00 119.26 ? 263 TYR A O   1 
ATOM 1673  C CB  . TYR A 1 263 ? -2.542  -31.064 -27.455 1.00 111.83 ? 263 TYR A CB  1 
ATOM 1674  C CG  . TYR A 1 263 ? -3.612  -30.030 -27.723 1.00 103.81 ? 263 TYR A CG  1 
ATOM 1675  C CD1 . TYR A 1 263 ? -3.841  -29.557 -29.010 1.00 109.46 ? 263 TYR A CD1 1 
ATOM 1676  C CD2 . TYR A 1 263 ? -4.392  -29.528 -26.690 1.00 105.38 ? 263 TYR A CD2 1 
ATOM 1677  C CE1 . TYR A 1 263 ? -4.817  -28.612 -29.258 1.00 104.52 ? 263 TYR A CE1 1 
ATOM 1678  C CE2 . TYR A 1 263 ? -5.372  -28.582 -26.931 1.00 102.45 ? 263 TYR A CE2 1 
ATOM 1679  C CZ  . TYR A 1 263 ? -5.580  -28.128 -28.216 1.00 102.90 ? 263 TYR A CZ  1 
ATOM 1680  O OH  . TYR A 1 263 ? -6.553  -27.186 -28.461 1.00 91.67  ? 263 TYR A OH  1 
ATOM 1681  N N   . PHE A 1 264 ? 0.404   -30.017 -28.988 1.00 109.89 ? 264 PHE A N   1 
ATOM 1682  C CA  . PHE A 1 264 ? 0.889   -29.295 -30.194 1.00 125.15 ? 264 PHE A CA  1 
ATOM 1683  C C   . PHE A 1 264 ? -0.059  -29.617 -31.351 1.00 127.33 ? 264 PHE A C   1 
ATOM 1684  O O   . PHE A 1 264 ? 0.274   -29.228 -32.493 1.00 127.83 ? 264 PHE A O   1 
ATOM 1685  C CB  . PHE A 1 264 ? 2.330   -29.709 -30.513 1.00 131.77 ? 264 PHE A CB  1 
ATOM 1686  C CG  . PHE A 1 264 ? 2.494   -31.060 -31.168 1.00 134.14 ? 264 PHE A CG  1 
ATOM 1687  C CD1 . PHE A 1 264 ? 2.269   -32.231 -30.460 1.00 133.48 ? 264 PHE A CD1 1 
ATOM 1688  C CD2 . PHE A 1 264 ? 2.889   -31.162 -32.493 1.00 136.93 ? 264 PHE A CD2 1 
ATOM 1689  C CE1 . PHE A 1 264 ? 2.419   -33.468 -31.066 1.00 141.23 ? 264 PHE A CE1 1 
ATOM 1690  C CE2 . PHE A 1 264 ? 3.036   -32.400 -33.098 1.00 132.46 ? 264 PHE A CE2 1 
ATOM 1691  C CZ  . PHE A 1 264 ? 2.804   -33.551 -32.383 1.00 139.70 ? 264 PHE A CZ  1 
ATOM 1692  N N   . LEU A 1 265 ? -1.182  -30.293 -31.061 1.00 120.69 ? 265 LEU A N   1 
ATOM 1693  C CA  . LEU A 1 265 ? -2.154  -30.724 -32.108 1.00 115.82 ? 265 LEU A CA  1 
ATOM 1694  C C   . LEU A 1 265 ? -1.441  -31.700 -33.049 1.00 115.29 ? 265 LEU A C   1 
ATOM 1695  O O   . LEU A 1 265 ? -0.664  -32.535 -32.542 1.00 121.53 ? 265 LEU A O   1 
ATOM 1696  C CB  . LEU A 1 265 ? -2.742  -29.518 -32.853 1.00 110.10 ? 265 LEU A CB  1 
ATOM 1697  C CG  . LEU A 1 265 ? -3.699  -29.845 -33.999 1.00 113.53 ? 265 LEU A CG  1 
ATOM 1698  C CD1 . LEU A 1 265 ? -4.936  -30.567 -33.489 1.00 109.92 ? 265 LEU A CD1 1 
ATOM 1699  C CD2 . LEU A 1 265 ? -4.087  -28.586 -34.761 1.00 111.61 ? 265 LEU A CD2 1 
ATOM 1700  N N   . SER A 1 266 ? -1.704  -31.605 -34.353 1.00 105.42 ? 266 SER A N   1 
ATOM 1701  C CA  . SER A 1 266 ? -1.022  -32.476 -35.344 1.00 106.06 ? 266 SER A CA  1 
ATOM 1702  C C   . SER A 1 266 ? -1.050  -31.770 -36.698 1.00 103.76 ? 266 SER A C   1 
ATOM 1703  O O   . SER A 1 266 ? -1.746  -30.769 -36.794 1.00 107.28 ? 266 SER A O   1 
ATOM 1704  C CB  . SER A 1 266 ? -1.689  -33.823 -35.432 1.00 103.21 ? 266 SER A CB  1 
ATOM 1705  O OG  . SER A 1 266 ? -2.950  -33.718 -36.074 1.00 107.86 ? 266 SER A OG  1 
ATOM 1706  N N   . ASN A 1 267 ? -0.316  -32.271 -37.692 1.00 104.48 ? 267 ASN A N   1 
ATOM 1707  C CA  . ASN A 1 267 ? -0.347  -31.691 -39.060 1.00 103.52 ? 267 ASN A CA  1 
ATOM 1708  C C   . ASN A 1 267 ? -1.786  -31.686 -39.577 1.00 105.11 ? 267 ASN A C   1 
ATOM 1709  O O   . ASN A 1 267 ? -2.066  -30.953 -40.538 1.00 103.04 ? 267 ASN A O   1 
ATOM 1710  C CB  . ASN A 1 267 ? 0.621   -32.383 -40.021 1.00 99.97  ? 267 ASN A CB  1 
ATOM 1711  C CG  . ASN A 1 267 ? 0.122   -33.712 -40.545 1.00 99.27  ? 267 ASN A CG  1 
ATOM 1712  O OD1 . ASN A 1 267 ? -0.308  -33.809 -41.691 1.00 95.17  ? 267 ASN A OD1 1 
ATOM 1713  N ND2 . ASN A 1 267 ? 0.202   -34.745 -39.724 1.00 101.57 ? 267 ASN A ND2 1 
ATOM 1714  N N   . GLU A 1 268 ? -2.663  -32.469 -38.951 1.00 102.12 ? 268 GLU A N   1 
ATOM 1715  C CA  . GLU A 1 268 ? -4.051  -32.550 -39.449 1.00 103.05 ? 268 GLU A CA  1 
ATOM 1716  C C   . GLU A 1 268 ? -4.858  -31.459 -38.759 1.00 103.72 ? 268 GLU A C   1 
ATOM 1717  O O   . GLU A 1 268 ? -5.768  -30.897 -39.394 1.00 103.51 ? 268 GLU A O   1 
ATOM 1718  C CB  . GLU A 1 268 ? -4.625  -33.928 -39.135 1.00 107.35 ? 268 GLU A CB  1 
ATOM 1719  C CG  . GLU A 1 268 ? -4.514  -34.903 -40.293 1.00 105.16 ? 268 GLU A CG  1 
ATOM 1720  C CD  . GLU A 1 268 ? -3.132  -35.502 -40.493 1.00 106.60 ? 268 GLU A CD  1 
ATOM 1721  O OE1 . GLU A 1 268 ? -2.467  -35.793 -39.482 1.00 110.19 ? 268 GLU A OE1 1 
ATOM 1722  O OE2 . GLU A 1 268 ? -2.724  -35.672 -41.658 1.00 96.70  ? 268 GLU A OE2 1 
ATOM 1723  N N   . GLU A 1 269 ? -4.522  -31.185 -37.503 1.00 98.49  ? 269 GLU A N   1 
ATOM 1724  C CA  . GLU A 1 269 ? -5.292  -30.183 -36.737 1.00 98.25  ? 269 GLU A CA  1 
ATOM 1725  C C   . GLU A 1 269 ? -4.651  -28.811 -36.923 1.00 96.26  ? 269 GLU A C   1 
ATOM 1726  O O   . GLU A 1 269 ? -5.406  -27.831 -36.935 1.00 93.49  ? 269 GLU A O   1 
ATOM 1727  C CB  . GLU A 1 269 ? -5.433  -30.633 -35.288 1.00 107.72 ? 269 GLU A CB  1 
ATOM 1728  C CG  . GLU A 1 269 ? -5.930  -32.063 -35.161 1.00 111.72 ? 269 GLU A CG  1 
ATOM 1729  C CD  . GLU A 1 269 ? -6.885  -32.319 -34.006 1.00 119.71 ? 269 GLU A CD  1 
ATOM 1730  O OE1 . GLU A 1 269 ? -7.637  -31.394 -33.643 1.00 124.87 ? 269 GLU A OE1 1 
ATOM 1731  O OE2 . GLU A 1 269 ? -6.870  -33.443 -33.465 1.00 113.07 ? 269 GLU A OE2 1 
ATOM 1732  N N   . LEU A 1 270 ? -3.322  -28.736 -37.071 1.00 100.46 ? 270 LEU A N   1 
ATOM 1733  C CA  . LEU A 1 270 ? -2.779  -27.415 -37.362 1.00 93.71  ? 270 LEU A CA  1 
ATOM 1734  C C   . LEU A 1 270 ? -3.367  -26.844 -38.643 1.00 95.42  ? 270 LEU A C   1 
ATOM 1735  O O   . LEU A 1 270 ? -3.517  -25.624 -38.762 1.00 96.36  ? 270 LEU A O   1 
ATOM 1736  C CB  . LEU A 1 270 ? -1.255  -27.479 -37.478 1.00 91.28  ? 270 LEU A CB  1 
ATOM 1737  C CG  . LEU A 1 270 ? -0.424  -27.708 -36.214 1.00 88.90  ? 270 LEU A CG  1 
ATOM 1738  C CD1 . LEU A 1 270 ? 1.005   -28.072 -36.583 1.00 84.65  ? 270 LEU A CD1 1 
ATOM 1739  C CD2 . LEU A 1 270 ? -0.452  -26.485 -35.317 1.00 96.66  ? 270 LEU A CD2 1 
ATOM 1740  N N   . GLU A 1 271 ? -3.701  -27.705 -39.607 1.00 98.00  ? 271 GLU A N   1 
ATOM 1741  C CA  . GLU A 1 271 ? -4.244  -27.223 -40.875 1.00 94.22  ? 271 GLU A CA  1 
ATOM 1742  C C   . GLU A 1 271 ? -5.578  -26.512 -40.677 1.00 91.35  ? 271 GLU A C   1 
ATOM 1743  O O   . GLU A 1 271 ? -5.815  -25.430 -41.237 1.00 90.54  ? 271 GLU A O   1 
ATOM 1744  C CB  . GLU A 1 271 ? -4.395  -28.387 -41.856 1.00 102.73 ? 271 GLU A CB  1 
ATOM 1745  C CG  . GLU A 1 271 ? -3.323  -28.426 -42.931 1.00 108.41 ? 271 GLU A CG  1 
ATOM 1746  C CD  . GLU A 1 271 ? -3.422  -27.251 -43.884 1.00 117.76 ? 271 GLU A CD  1 
ATOM 1747  O OE1 . GLU A 1 271 ? -4.543  -26.952 -44.342 1.00 117.30 ? 271 GLU A OE1 1 
ATOM 1748  O OE2 . GLU A 1 271 ? -2.380  -26.624 -44.167 1.00 114.89 ? 271 GLU A OE2 1 
ATOM 1749  N N   . GLU A 1 272 ? -6.473  -27.112 -39.885 1.00 100.37 ? 272 GLU A N   1 
ATOM 1750  C CA  . GLU A 1 272 ? -7.815  -26.569 -39.718 1.00 98.01  ? 272 GLU A CA  1 
ATOM 1751  C C   . GLU A 1 272 ? -7.812  -25.218 -39.013 1.00 93.72  ? 272 GLU A C   1 
ATOM 1752  O O   . GLU A 1 272 ? -8.767  -24.451 -39.173 1.00 89.95  ? 272 GLU A O   1 
ATOM 1753  C CB  . GLU A 1 272 ? -8.692  -27.554 -38.941 1.00 98.02  ? 272 GLU A CB  1 
ATOM 1754  C CG  . GLU A 1 272 ? -8.821  -28.934 -39.576 1.00 96.42  ? 272 GLU A CG  1 
ATOM 1755  C CD  . GLU A 1 272 ? -9.909  -29.009 -40.637 1.00 96.75  ? 272 GLU A CD  1 
ATOM 1756  O OE1 . GLU A 1 272 ? -10.373 -27.947 -41.104 1.00 91.95  ? 272 GLU A OE1 1 
ATOM 1757  O OE2 . GLU A 1 272 ? -10.305 -30.138 -41.001 1.00 96.04  ? 272 GLU A OE2 1 
ATOM 1758  N N   . VAL A 1 273 ? -6.772  -24.912 -38.239 1.00 92.59  ? 273 VAL A N   1 
ATOM 1759  C CA  . VAL A 1 273 ? -6.712  -23.632 -37.540 1.00 97.73  ? 273 VAL A CA  1 
ATOM 1760  C C   . VAL A 1 273 ? -5.922  -22.636 -38.380 1.00 91.05  ? 273 VAL A C   1 
ATOM 1761  O O   . VAL A 1 273 ? -6.230  -21.440 -38.386 1.00 90.35  ? 273 VAL A O   1 
ATOM 1762  C CB  . VAL A 1 273 ? -6.116  -23.784 -36.125 1.00 96.91  ? 273 VAL A CB  1 
ATOM 1763  C CG1 . VAL A 1 273 ? -6.875  -24.847 -35.343 1.00 84.07  ? 273 VAL A CG1 1 
ATOM 1764  C CG2 . VAL A 1 273 ? -4.631  -24.116 -36.181 1.00 97.54  ? 273 VAL A CG2 1 
ATOM 1765  N N   . ALA A 1 274 ? -4.937  -23.121 -39.143 1.00 87.71  ? 274 ALA A N   1 
ATOM 1766  C CA  . ALA A 1 274 ? -4.153  -22.225 -39.985 1.00 85.76  ? 274 ALA A CA  1 
ATOM 1767  C C   . ALA A 1 274 ? -5.001  -21.659 -41.118 1.00 84.37  ? 274 ALA A C   1 
ATOM 1768  O O   . ALA A 1 274 ? -5.018  -20.444 -41.350 1.00 88.50  ? 274 ALA A O   1 
ATOM 1769  C CB  . ALA A 1 274 ? -2.930  -22.955 -40.534 1.00 85.86  ? 274 ALA A CB  1 
ATOM 1770  N N   . ILE A 1 275 ? -5.718  -22.527 -41.837 1.00 85.51  ? 275 ILE A N   1 
ATOM 1771  C CA  . ILE A 1 275 ? -6.566  -22.030 -42.916 1.00 95.88  ? 275 ILE A CA  1 
ATOM 1772  C C   . ILE A 1 275 ? -7.753  -21.257 -42.349 1.00 96.53  ? 275 ILE A C   1 
ATOM 1773  O O   . ILE A 1 275 ? -8.247  -20.313 -42.980 1.00 93.99  ? 275 ILE A O   1 
ATOM 1774  C CB  . ILE A 1 275 ? -7.009  -23.190 -43.826 1.00 99.22  ? 275 ILE A CB  1 
ATOM 1775  C CG1 . ILE A 1 275 ? -5.784  -23.936 -44.352 1.00 101.45 ? 275 ILE A CG1 1 
ATOM 1776  C CG2 . ILE A 1 275 ? -7.841  -22.676 -44.991 1.00 99.67  ? 275 ILE A CG2 1 
ATOM 1777  C CD1 . ILE A 1 275 ? -4.792  -23.045 -45.080 1.00 96.93  ? 275 ILE A CD1 1 
ATOM 1778  N N   . GLY A 1 276 ? -8.218  -21.623 -41.151 1.00 95.10  ? 276 GLY A N   1 
ATOM 1779  C CA  . GLY A 1 276 ? -9.262  -20.848 -40.504 1.00 93.73  ? 276 GLY A CA  1 
ATOM 1780  C C   . GLY A 1 276 ? -8.815  -19.446 -40.136 1.00 91.10  ? 276 GLY A C   1 
ATOM 1781  O O   . GLY A 1 276 ? -9.612  -18.504 -40.175 1.00 87.67  ? 276 GLY A O   1 
ATOM 1782  N N   . LEU A 1 277 ? -7.544  -19.286 -39.765 1.00 89.25  ? 277 LEU A N   1 
ATOM 1783  C CA  . LEU A 1 277 ? -6.990  -17.959 -39.529 1.00 86.59  ? 277 LEU A CA  1 
ATOM 1784  C C   . LEU A 1 277 ? -6.726  -17.217 -40.831 1.00 94.46  ? 277 LEU A C   1 
ATOM 1785  O O   . LEU A 1 277 ? -6.782  -15.981 -40.856 1.00 92.36  ? 277 LEU A O   1 
ATOM 1786  C CB  . LEU A 1 277 ? -5.697  -18.062 -38.719 1.00 81.28  ? 277 LEU A CB  1 
ATOM 1787  C CG  . LEU A 1 277 ? -5.842  -18.408 -37.236 1.00 73.01  ? 277 LEU A CG  1 
ATOM 1788  C CD1 . LEU A 1 277 ? -4.484  -18.699 -36.621 1.00 75.00  ? 277 LEU A CD1 1 
ATOM 1789  C CD2 . LEU A 1 277 ? -6.532  -17.276 -36.495 1.00 75.63  ? 277 LEU A CD2 1 
ATOM 1790  N N   . GLU A 1 278 ? -6.437  -17.942 -41.916 1.00 100.65 ? 278 GLU A N   1 
ATOM 1791  C CA  . GLU A 1 278 ? -6.209  -17.280 -43.198 1.00 95.65  ? 278 GLU A CA  1 
ATOM 1792  C C   . GLU A 1 278 ? -7.488  -16.637 -43.719 1.00 90.52  ? 278 GLU A C   1 
ATOM 1793  O O   . GLU A 1 278 ? -7.493  -15.457 -44.090 1.00 91.42  ? 278 GLU A O   1 
ATOM 1794  C CB  . GLU A 1 278 ? -5.653  -18.274 -44.222 1.00 98.29  ? 278 GLU A CB  1 
ATOM 1795  C CG  . GLU A 1 278 ? -5.407  -17.654 -45.593 1.00 107.24 ? 278 GLU A CG  1 
ATOM 1796  C CD  . GLU A 1 278 ? -4.793  -18.630 -46.580 1.00 105.29 ? 278 GLU A CD  1 
ATOM 1797  O OE1 . GLU A 1 278 ? -4.537  -19.790 -46.195 1.00 102.16 ? 278 GLU A OE1 1 
ATOM 1798  O OE2 . GLU A 1 278 ? -4.563  -18.233 -47.742 1.00 98.43  ? 278 GLU A OE2 1 
ATOM 1799  N N   . ILE A 1 279 ? -8.589  -17.395 -43.755 1.00 90.06  ? 279 ILE A N   1 
ATOM 1800  C CA  . ILE A 1 279 ? -9.850  -16.866 -44.273 1.00 93.38  ? 279 ILE A CA  1 
ATOM 1801  C C   . ILE A 1 279 ? -10.573 -15.982 -43.270 1.00 92.64  ? 279 ILE A C   1 
ATOM 1802  O O   . ILE A 1 279 ? -11.630 -15.427 -43.600 1.00 93.34  ? 279 ILE A O   1 
ATOM 1803  C CB  . ILE A 1 279 ? -10.796 -18.000 -44.719 1.00 93.22  ? 279 ILE A CB  1 
ATOM 1804  C CG1 . ILE A 1 279 ? -11.252 -18.827 -43.517 1.00 97.65  ? 279 ILE A CG1 1 
ATOM 1805  C CG2 . ILE A 1 279 ? -10.110 -18.889 -45.743 1.00 98.76  ? 279 ILE A CG2 1 
ATOM 1806  C CD1 . ILE A 1 279 ? -12.299 -19.864 -43.863 1.00 101.87 ? 279 ILE A CD1 1 
ATOM 1807  N N   . SER A 1 280 ? -10.039 -15.831 -42.056 1.00 87.05  ? 280 SER A N   1 
ATOM 1808  C CA  . SER A 1 280 ? -10.634 -14.915 -41.090 1.00 89.85  ? 280 SER A CA  1 
ATOM 1809  C C   . SER A 1 280 ? -10.422 -13.457 -41.473 1.00 88.78  ? 280 SER A C   1 
ATOM 1810  O O   . SER A 1 280 ? -11.184 -12.597 -41.022 1.00 90.54  ? 280 SER A O   1 
ATOM 1811  C CB  . SER A 1 280 ? -10.059 -15.176 -39.697 1.00 88.76  ? 280 SER A CB  1 
ATOM 1812  O OG  . SER A 1 280 ? -10.362 -16.490 -39.259 1.00 95.51  ? 280 SER A OG  1 
ATOM 1813  N N   . THR A 1 281 ? -9.409  -13.170 -42.297 1.00 90.34  ? 281 THR A N   1 
ATOM 1814  C CA  . THR A 1 281 ? -9.114  -11.818 -42.781 1.00 89.57  ? 281 THR A CA  1 
ATOM 1815  C C   . THR A 1 281 ? -8.948  -10.833 -41.622 1.00 82.84  ? 281 THR A C   1 
ATOM 1816  O O   . THR A 1 281 ? -9.534  -9.749  -41.606 1.00 85.37  ? 281 THR A O   1 
ATOM 1817  C CB  . THR A 1 281 ? -10.187 -11.333 -43.763 1.00 96.10  ? 281 THR A CB  1 
ATOM 1818  O OG1 . THR A 1 281 ? -11.417 -11.101 -43.065 1.00 99.55  ? 281 THR A OG1 1 
ATOM 1819  C CG2 . THR A 1 281 ? -10.415 -12.369 -44.856 1.00 94.77  ? 281 THR A CG2 1 
ATOM 1820  N N   . VAL A 1 282 ? -8.132  -11.219 -40.641 1.00 74.61  ? 282 VAL A N   1 
ATOM 1821  C CA  . VAL A 1 282 ? -7.844  -10.372 -39.493 1.00 72.94  ? 282 VAL A CA  1 
ATOM 1822  C C   . VAL A 1 282 ? -6.422  -10.653 -39.031 1.00 69.37  ? 282 VAL A C   1 
ATOM 1823  O O   . VAL A 1 282 ? -5.911  -11.768 -39.177 1.00 65.51  ? 282 VAL A O   1 
ATOM 1824  C CB  . VAL A 1 282 ? -8.867  -10.588 -38.351 1.00 73.42  ? 282 VAL A CB  1 
ATOM 1825  C CG1 . VAL A 1 282 ? -8.648  -11.928 -37.665 1.00 78.80  ? 282 VAL A CG1 1 
ATOM 1826  C CG2 . VAL A 1 282 ? -8.813  -9.441  -37.350 1.00 66.58  ? 282 VAL A CG2 1 
ATOM 1827  N N   . ASN A 1 283 ? -5.773  -9.623  -38.491 1.00 64.79  ? 283 ASN A N   1 
ATOM 1828  C CA  . ASN A 1 283 ? -4.415  -9.768  -37.988 1.00 65.35  ? 283 ASN A CA  1 
ATOM 1829  C C   . ASN A 1 283 ? -4.385  -10.738 -36.813 1.00 66.29  ? 283 ASN A C   1 
ATOM 1830  O O   . ASN A 1 283 ? -5.322  -10.812 -36.017 1.00 66.96  ? 283 ASN A O   1 
ATOM 1831  C CB  . ASN A 1 283 ? -3.863  -8.410  -37.555 1.00 70.99  ? 283 ASN A CB  1 
ATOM 1832  C CG  . ASN A 1 283 ? -4.091  -7.332  -38.593 1.00 75.21  ? 283 ASN A CG  1 
ATOM 1833  O OD1 . ASN A 1 283 ? -3.974  -7.578  -39.794 1.00 70.87  ? 283 ASN A OD1 1 
ATOM 1834  N ND2 . ASN A 1 283 ? -4.423  -6.131  -38.134 1.00 75.90  ? 283 ASN A ND2 1 
ATOM 1835  N N   . PHE A 1 284 ? -3.288  -11.478 -36.696 1.00 62.40  ? 284 PHE A N   1 
ATOM 1836  C CA  . PHE A 1 284 ? -3.185  -12.465 -35.632 1.00 63.58  ? 284 PHE A CA  1 
ATOM 1837  C C   . PHE A 1 284 ? -1.728  -12.676 -35.250 1.00 65.85  ? 284 PHE A C   1 
ATOM 1838  O O   . PHE A 1 284 ? -0.815  -12.458 -36.052 1.00 70.72  ? 284 PHE A O   1 
ATOM 1839  C CB  . PHE A 1 284 ? -3.820  -13.802 -36.041 1.00 62.12  ? 284 PHE A CB  1 
ATOM 1840  C CG  . PHE A 1 284 ? -3.059  -14.534 -37.108 1.00 62.71  ? 284 PHE A CG  1 
ATOM 1841  C CD1 . PHE A 1 284 ? -3.262  -14.242 -38.445 1.00 71.40  ? 284 PHE A CD1 1 
ATOM 1842  C CD2 . PHE A 1 284 ? -2.142  -15.518 -36.774 1.00 69.58  ? 284 PHE A CD2 1 
ATOM 1843  C CE1 . PHE A 1 284 ? -2.562  -14.911 -39.428 1.00 76.40  ? 284 PHE A CE1 1 
ATOM 1844  C CE2 . PHE A 1 284 ? -1.439  -16.190 -37.753 1.00 72.15  ? 284 PHE A CE2 1 
ATOM 1845  C CZ  . PHE A 1 284 ? -1.650  -15.889 -39.082 1.00 70.40  ? 284 PHE A CZ  1 
ATOM 1846  N N   . ILE A 1 285 ? -1.530  -13.097 -34.007 1.00 68.21  ? 285 ILE A N   1 
ATOM 1847  C CA  . ILE A 1 285 ? -0.251  -13.600 -33.520 1.00 66.52  ? 285 ILE A CA  1 
ATOM 1848  C C   . ILE A 1 285 ? -0.520  -15.009 -33.010 1.00 70.42  ? 285 ILE A C   1 
ATOM 1849  O O   . ILE A 1 285 ? -1.029  -15.192 -31.900 1.00 65.12  ? 285 ILE A O   1 
ATOM 1850  C CB  . ILE A 1 285 ? 0.354   -12.714 -32.428 1.00 61.07  ? 285 ILE A CB  1 
ATOM 1851  C CG1 . ILE A 1 285 ? 0.542   -11.289 -32.942 1.00 60.04  ? 285 ILE A CG1 1 
ATOM 1852  C CG2 . ILE A 1 285 ? 1.683   -13.288 -31.958 1.00 51.54  ? 285 ILE A CG2 1 
ATOM 1853  C CD1 . ILE A 1 285 ? 1.240   -10.373 -31.960 1.00 65.71  ? 285 ILE A CD1 1 
ATOM 1854  N N   . TRP A 1 286 ? -0.206  -16.008 -33.829 1.00 74.73  ? 286 TRP A N   1 
ATOM 1855  C CA  . TRP A 1 286 ? -0.464  -17.409 -33.506 1.00 72.65  ? 286 TRP A CA  1 
ATOM 1856  C C   . TRP A 1 286 ? 0.841   -18.030 -33.021 1.00 70.24  ? 286 TRP A C   1 
ATOM 1857  O O   . TRP A 1 286 ? 1.704   -18.395 -33.820 1.00 79.86  ? 286 TRP A O   1 
ATOM 1858  C CB  . TRP A 1 286 ? -1.018  -18.146 -34.719 1.00 77.56  ? 286 TRP A CB  1 
ATOM 1859  C CG  . TRP A 1 286 ? -1.124  -19.630 -34.552 1.00 86.81  ? 286 TRP A CG  1 
ATOM 1860  C CD1 . TRP A 1 286 ? -1.297  -20.319 -33.384 1.00 81.06  ? 286 TRP A CD1 1 
ATOM 1861  C CD2 . TRP A 1 286 ? -1.054  -20.612 -35.590 1.00 88.91  ? 286 TRP A CD2 1 
ATOM 1862  N NE1 . TRP A 1 286 ? -1.341  -21.669 -33.633 1.00 85.60  ? 286 TRP A NE1 1 
ATOM 1863  C CE2 . TRP A 1 286 ? -1.196  -21.875 -34.980 1.00 88.52  ? 286 TRP A CE2 1 
ATOM 1864  C CE3 . TRP A 1 286 ? -0.888  -20.548 -36.976 1.00 86.08  ? 286 TRP A CE3 1 
ATOM 1865  C CZ2 . TRP A 1 286 ? -1.175  -23.062 -35.710 1.00 90.18  ? 286 TRP A CZ2 1 
ATOM 1866  C CZ3 . TRP A 1 286 ? -0.868  -21.728 -37.698 1.00 89.52  ? 286 TRP A CZ3 1 
ATOM 1867  C CH2 . TRP A 1 286 ? -1.012  -22.968 -37.064 1.00 88.76  ? 286 TRP A CH2 1 
ATOM 1868  N N   . ALA A 1 287 ? 0.978   -18.153 -31.702 1.00 65.78  ? 287 ALA A N   1 
ATOM 1869  C CA  . ALA A 1 287 ? 2.161   -18.751 -31.095 1.00 71.05  ? 287 ALA A CA  1 
ATOM 1870  C C   . ALA A 1 287 ? 1.946   -20.255 -30.997 1.00 75.62  ? 287 ALA A C   1 
ATOM 1871  O O   . ALA A 1 287 ? 1.094   -20.719 -30.230 1.00 71.43  ? 287 ALA A O   1 
ATOM 1872  C CB  . ALA A 1 287 ? 2.429   -18.141 -29.724 1.00 70.52  ? 287 ALA A CB  1 
ATOM 1873  N N   . VAL A 1 288 ? 2.673   -20.997 -31.839 1.00 76.53  ? 288 VAL A N   1 
ATOM 1874  C CA  . VAL A 1 288 ? 2.485   -22.472 -31.955 1.00 78.07  ? 288 VAL A CA  1 
ATOM 1875  C C   . VAL A 1 288 ? 3.415   -23.207 -30.990 1.00 72.97  ? 288 VAL A C   1 
ATOM 1876  O O   . VAL A 1 288 ? 4.056   -22.523 -30.206 1.00 77.79  ? 288 VAL A O   1 
ATOM 1877  C CB  . VAL A 1 288 ? 2.655   -22.904 -33.423 1.00 82.54  ? 288 VAL A CB  1 
ATOM 1878  C CG1 . VAL A 1 288 ? 4.107   -23.074 -33.843 1.00 83.68  ? 288 VAL A CG1 1 
ATOM 1879  C CG2 . VAL A 1 288 ? 1.826   -24.126 -33.780 1.00 82.79  ? 288 VAL A CG2 1 
ATOM 1880  N N   . PHE A 1 303 ? -1.807  -19.926 -46.520 1.00 88.44  ? 303 PHE A N   1 
ATOM 1881  C CA  . PHE A 1 303 ? -0.975  -19.727 -45.307 1.00 83.17  ? 303 PHE A CA  1 
ATOM 1882  C C   . PHE A 1 303 ? 0.489   -19.904 -45.690 1.00 82.35  ? 303 PHE A C   1 
ATOM 1883  O O   . PHE A 1 303 ? 1.130   -18.887 -45.976 1.00 87.63  ? 303 PHE A O   1 
ATOM 1884  C CB  . PHE A 1 303 ? -1.367  -20.729 -44.220 1.00 84.61  ? 303 PHE A CB  1 
ATOM 1885  C CG  . PHE A 1 303 ? -1.218  -20.219 -42.812 1.00 78.79  ? 303 PHE A CG  1 
ATOM 1886  C CD1 . PHE A 1 303 ? -2.145  -19.341 -42.278 1.00 81.13  ? 303 PHE A CD1 1 
ATOM 1887  C CD2 . PHE A 1 303 ? -0.149  -20.614 -42.028 1.00 76.93  ? 303 PHE A CD2 1 
ATOM 1888  C CE1 . PHE A 1 303 ? -2.007  -18.872 -40.984 1.00 87.40  ? 303 PHE A CE1 1 
ATOM 1889  C CE2 . PHE A 1 303 ? -0.011  -20.141 -40.734 1.00 76.64  ? 303 PHE A CE2 1 
ATOM 1890  C CZ  . PHE A 1 303 ? -0.939  -19.270 -40.216 1.00 86.69  ? 303 PHE A CZ  1 
ATOM 1891  N N   . VAL A 1 304 ? 0.988   -21.144 -45.677 1.00 87.39  ? 304 VAL A N   1 
ATOM 1892  C CA  . VAL A 1 304 ? 2.413   -21.455 -46.014 1.00 93.77  ? 304 VAL A CA  1 
ATOM 1893  C C   . VAL A 1 304 ? 3.367   -20.413 -45.393 1.00 100.37 ? 304 VAL A C   1 
ATOM 1894  O O   . VAL A 1 304 ? 4.469   -20.221 -45.949 1.00 99.80  ? 304 VAL A O   1 
ATOM 1895  C CB  . VAL A 1 304 ? 2.607   -21.729 -47.522 1.00 79.27  ? 304 VAL A CB  1 
ATOM 1896  C CG1 . VAL A 1 304 ? 2.735   -20.476 -48.374 1.00 87.28  ? 304 VAL A CG1 1 
ATOM 1897  C CG2 . VAL A 1 304 ? 3.735   -22.711 -47.799 1.00 81.95  ? 304 VAL A CG2 1 
ATOM 1898  N N   . GLN A 1 305 ? 2.987   -19.793 -44.265 1.00 90.84  ? 305 GLN A N   1 
ATOM 1899  C CA  . GLN A 1 305 ? 3.821   -18.780 -43.552 1.00 89.94  ? 305 GLN A CA  1 
ATOM 1900  C C   . GLN A 1 305 ? 4.085   -17.530 -44.399 1.00 95.38  ? 305 GLN A C   1 
ATOM 1901  O O   . GLN A 1 305 ? 4.480   -16.511 -43.806 1.00 95.80  ? 305 GLN A O   1 
ATOM 1902  C CB  . GLN A 1 305 ? 5.080   -19.415 -42.954 1.00 98.30  ? 305 GLN A CB  1 
ATOM 1903  C CG  . GLN A 1 305 ? 4.831   -20.401 -41.820 1.00 112.67 ? 305 GLN A CG  1 
ATOM 1904  C CD  . GLN A 1 305 ? 6.104   -21.043 -41.325 1.00 118.87 ? 305 GLN A CD  1 
ATOM 1905  O OE1 . GLN A 1 305 ? 7.094   -21.145 -42.046 1.00 118.54 ? 305 GLN A OE1 1 
ATOM 1906  N NE2 . GLN A 1 305 ? 6.086   -21.487 -40.079 1.00 114.60 ? 305 GLN A NE2 1 
ATOM 1907  N N   . ARG A 1 306 ? 3.825   -17.578 -45.709 1.00 93.58  ? 306 ARG A N   1 
ATOM 1908  C CA  . ARG A 1 306 ? 4.183   -16.433 -46.591 1.00 86.02  ? 306 ARG A CA  1 
ATOM 1909  C C   . ARG A 1 306 ? 2.928   -15.787 -47.169 1.00 78.04  ? 306 ARG A C   1 
ATOM 1910  O O   . ARG A 1 306 ? 3.045   -14.678 -47.705 1.00 77.43  ? 306 ARG A O   1 
ATOM 1911  C CB  . ARG A 1 306 ? 5.151   -16.893 -47.681 1.00 86.67  ? 306 ARG A CB  1 
ATOM 1912  C CG  . ARG A 1 306 ? 6.599   -16.988 -47.221 1.00 87.87  ? 306 ARG A CG  1 
ATOM 1913  C CD  . ARG A 1 306 ? 7.037   -15.787 -46.403 1.00 94.47  ? 306 ARG A CD  1 
ATOM 1914  N NE  . ARG A 1 306 ? 7.139   -14.570 -47.199 1.00 101.18 ? 306 ARG A NE  1 
ATOM 1915  C CZ  . ARG A 1 306 ? 6.685   -13.381 -46.822 1.00 98.35  ? 306 ARG A CZ  1 
ATOM 1916  N NH1 . ARG A 1 306 ? 6.093   -13.238 -45.649 1.00 102.03 ? 306 ARG A NH1 1 
ATOM 1917  N NH2 . ARG A 1 306 ? 6.825   -12.338 -47.619 1.00 99.27  ? 306 ARG A NH2 1 
ATOM 1918  N N   . VAL A 1 307 ? 1.784   -16.458 -47.070 1.00 82.92  ? 307 VAL A N   1 
ATOM 1919  C CA  . VAL A 1 307 ? 0.493   -15.866 -47.536 1.00 82.14  ? 307 VAL A CA  1 
ATOM 1920  C C   . VAL A 1 307 ? -0.414  -15.710 -46.310 1.00 85.46  ? 307 VAL A C   1 
ATOM 1921  O O   . VAL A 1 307 ? -1.601  -15.373 -46.489 1.00 91.14  ? 307 VAL A O   1 
ATOM 1922  C CB  . VAL A 1 307 ? -0.176  -16.715 -48.635 1.00 83.70  ? 307 VAL A CB  1 
ATOM 1923  C CG1 . VAL A 1 307 ? -1.544  -16.172 -49.016 1.00 85.12  ? 307 VAL A CG1 1 
ATOM 1924  C CG2 . VAL A 1 307 ? 0.701   -16.842 -49.871 1.00 87.76  ? 307 VAL A CG2 1 
ATOM 1925  N N   . GLY A 1 308 ? 0.194   -15.671 -45.121 1.00 86.51  ? 308 GLY A N   1 
ATOM 1926  C CA  . GLY A 1 308 ? -0.591  -15.411 -43.900 1.00 81.45  ? 308 GLY A CA  1 
ATOM 1927  C C   . GLY A 1 308 ? -1.137  -14.001 -43.940 1.00 85.68  ? 308 GLY A C   1 
ATOM 1928  O O   . GLY A 1 308 ? -0.324  -13.084 -44.129 1.00 83.28  ? 308 GLY A O   1 
ATOM 1929  N N   . ASP A 1 309 ? -2.460  -13.833 -43.804 1.00 90.21  ? 309 ASP A N   1 
ATOM 1930  C CA  . ASP A 1 309 ? -3.105  -12.492 -43.869 1.00 80.16  ? 309 ASP A CA  1 
ATOM 1931  C C   . ASP A 1 309 ? -2.651  -11.667 -42.675 1.00 81.51  ? 309 ASP A C   1 
ATOM 1932  O O   . ASP A 1 309 ? -3.424  -11.567 -41.714 1.00 81.46  ? 309 ASP A O   1 
ATOM 1933  C CB  . ASP A 1 309 ? -4.631  -12.576 -43.896 1.00 82.52  ? 309 ASP A CB  1 
ATOM 1934  C CG  . ASP A 1 309 ? -5.299  -11.324 -44.432 1.00 84.32  ? 309 ASP A CG  1 
ATOM 1935  O OD1 . ASP A 1 309 ? -5.398  -11.196 -45.666 1.00 101.55 ? 309 ASP A OD1 1 
ATOM 1936  O OD2 . ASP A 1 309 ? -5.719  -10.486 -43.613 1.00 82.12  ? 309 ASP A OD2 1 
ATOM 1937  N N   . ARG A 1 310 ? -1.435  -11.132 -42.734 1.00 80.58  ? 310 ARG A N   1 
ATOM 1938  C CA  . ARG A 1 310 ? -0.922  -10.257 -41.655 1.00 76.13  ? 310 ARG A CA  1 
ATOM 1939  C C   . ARG A 1 310 ? -0.915  -11.013 -40.328 1.00 74.48  ? 310 ARG A C   1 
ATOM 1940  O O   . ARG A 1 310 ? -1.764  -10.724 -39.479 1.00 64.37  ? 310 ARG A O   1 
ATOM 1941  C CB  . ARG A 1 310 ? -1.711  -8.949  -41.653 1.00 75.04  ? 310 ARG A CB  1 
ATOM 1942  C CG  . ARG A 1 310 ? -1.544  -8.129  -42.925 1.00 68.56  ? 310 ARG A CG  1 
ATOM 1943  C CD  . ARG A 1 310 ? -0.089  -7.825  -43.222 1.00 73.35  ? 310 ARG A CD  1 
ATOM 1944  N NE  . ARG A 1 310 ? 0.460   -8.650  -44.288 1.00 73.65  ? 310 ARG A NE  1 
ATOM 1945  C CZ  . ARG A 1 310 ? 1.518   -9.443  -44.157 1.00 84.31  ? 310 ARG A CZ  1 
ATOM 1946  N NH1 . ARG A 1 310 ? 2.149   -9.522  -42.998 1.00 78.45  ? 310 ARG A NH1 1 
ATOM 1947  N NH2 . ARG A 1 310 ? 1.942   -10.156 -45.184 1.00 89.46  ? 310 ARG A NH2 1 
ATOM 1948  N N   . GLY A 1 311 ? 0.031   -11.939 -40.171 1.00 77.44  ? 311 GLY A N   1 
ATOM 1949  C CA  . GLY A 1 311 ? 0.156   -12.696 -38.914 1.00 69.57  ? 311 GLY A CA  1 
ATOM 1950  C C   . GLY A 1 311 ? 1.601   -12.992 -38.576 1.00 68.44  ? 311 GLY A C   1 
ATOM 1951  O O   . GLY A 1 311 ? 2.466   -12.690 -39.409 1.00 68.77  ? 311 GLY A O   1 
ATOM 1952  N N   . LEU A 1 312 ? 1.849   -13.569 -37.399 1.00 65.18  ? 312 LEU A N   1 
ATOM 1953  C CA  . LEU A 1 312 ? 3.227   -13.931 -36.980 1.00 60.56  ? 312 LEU A CA  1 
ATOM 1954  C C   . LEU A 1 312 ? 3.188   -15.230 -36.175 1.00 60.94  ? 312 LEU A C   1 
ATOM 1955  O O   . LEU A 1 312 ? 2.510   -15.255 -35.147 1.00 67.64  ? 312 LEU A O   1 
ATOM 1956  C CB  . LEU A 1 312 ? 3.799   -12.785 -36.143 1.00 60.33  ? 312 LEU A CB  1 
ATOM 1957  C CG  . LEU A 1 312 ? 5.237   -12.949 -35.656 1.00 67.94  ? 312 LEU A CG  1 
ATOM 1958  C CD1 . LEU A 1 312 ? 6.144   -13.426 -36.777 1.00 66.82  ? 312 LEU A CD1 1 
ATOM 1959  C CD2 . LEU A 1 312 ? 5.754   -11.643 -35.080 1.00 72.15  ? 312 LEU A CD2 1 
ATOM 1960  N N   . VAL A 1 313 ? 3.902   -16.259 -36.629 1.00 59.54  ? 313 VAL A N   1 
ATOM 1961  C CA  . VAL A 1 313 ? 3.962   -17.519 -35.896 1.00 64.93  ? 313 VAL A CA  1 
ATOM 1962  C C   . VAL A 1 313 ? 5.237   -17.545 -35.068 1.00 68.64  ? 313 VAL A C   1 
ATOM 1963  O O   . VAL A 1 313 ? 6.302   -17.105 -35.522 1.00 62.63  ? 313 VAL A O   1 
ATOM 1964  C CB  . VAL A 1 313 ? 3.891   -18.729 -36.849 1.00 66.31  ? 313 VAL A CB  1 
ATOM 1965  C CG1 . VAL A 1 313 ? 2.519   -18.808 -37.500 1.00 75.57  ? 313 VAL A CG1 1 
ATOM 1966  C CG2 . VAL A 1 313 ? 4.980   -18.646 -37.909 1.00 83.44  ? 313 VAL A CG2 1 
ATOM 1967  N N   . VAL A 1 314 ? 5.131   -18.051 -33.842 1.00 67.83  ? 314 VAL A N   1 
ATOM 1968  C CA  . VAL A 1 314 ? 6.250   -18.120 -32.911 1.00 65.89  ? 314 VAL A CA  1 
ATOM 1969  C C   . VAL A 1 314 ? 6.432   -19.570 -32.480 1.00 70.17  ? 314 VAL A C   1 
ATOM 1970  O O   . VAL A 1 314 ? 5.453   -20.312 -32.344 1.00 74.84  ? 314 VAL A O   1 
ATOM 1971  C CB  . VAL A 1 314 ? 6.029   -17.208 -31.684 1.00 65.47  ? 314 VAL A CB  1 
ATOM 1972  C CG1 . VAL A 1 314 ? 7.316   -17.065 -30.882 1.00 73.40  ? 314 VAL A CG1 1 
ATOM 1973  C CG2 . VAL A 1 314 ? 5.511   -15.843 -32.120 1.00 60.43  ? 314 VAL A CG2 1 
ATOM 1974  N N   . GLU A 1 315 ? 7.685   -19.968 -32.266 1.00 70.63  ? 315 GLU A N   1 
ATOM 1975  C CA  . GLU A 1 315 ? 7.999   -21.339 -31.882 1.00 80.84  ? 315 GLU A CA  1 
ATOM 1976  C C   . GLU A 1 315 ? 7.651   -21.606 -30.424 1.00 81.49  ? 315 GLU A C   1 
ATOM 1977  O O   . GLU A 1 315 ? 6.694   -22.332 -30.130 1.00 76.70  ? 315 GLU A O   1 
ATOM 1978  C CB  . GLU A 1 315 ? 9.479   -21.639 -32.130 1.00 84.77  ? 315 GLU A CB  1 
ATOM 1979  C CG  . GLU A 1 315 ? 9.912   -23.030 -31.693 1.00 82.71  ? 315 GLU A CG  1 
ATOM 1980  C CD  . GLU A 1 315 ? 11.031  -23.001 -30.668 1.00 79.07  ? 315 GLU A CD  1 
ATOM 1981  O OE1 . GLU A 1 315 ? 11.695  -21.952 -30.539 1.00 80.29  ? 315 GLU A OE1 1 
ATOM 1982  O OE2 . GLU A 1 315 ? 11.244  -24.028 -29.988 1.00 74.13  ? 315 GLU A OE2 1 
ATOM 1983  N N   . GLY A 1 316 ? 8.417   -21.023 -29.505 1.00 81.02  ? 316 GLY A N   1 
ATOM 1984  C CA  . GLY A 1 316 ? 8.265   -21.320 -28.093 1.00 79.03  ? 316 GLY A CA  1 
ATOM 1985  C C   . GLY A 1 316 ? 7.458   -20.307 -27.310 1.00 74.04  ? 316 GLY A C   1 
ATOM 1986  O O   . GLY A 1 316 ? 6.313   -20.007 -27.663 1.00 75.48  ? 316 GLY A O   1 
ATOM 1987  N N   . TRP A 1 317 ? 8.045   -19.777 -26.240 1.00 75.69  ? 317 TRP A N   1 
ATOM 1988  C CA  . TRP A 1 317 ? 7.323   -18.879 -25.350 1.00 70.41  ? 317 TRP A CA  1 
ATOM 1989  C C   . TRP A 1 317 ? 7.010   -17.560 -26.048 1.00 79.87  ? 317 TRP A C   1 
ATOM 1990  O O   . TRP A 1 317 ? 7.840   -17.006 -26.774 1.00 74.29  ? 317 TRP A O   1 
ATOM 1991  C CB  . TRP A 1 317 ? 8.131   -18.623 -24.078 1.00 77.08  ? 317 TRP A CB  1 
ATOM 1992  C CG  . TRP A 1 317 ? 8.356   -19.851 -23.243 1.00 81.67  ? 317 TRP A CG  1 
ATOM 1993  C CD1 . TRP A 1 317 ? 7.400   -20.635 -22.663 1.00 81.46  ? 317 TRP A CD1 1 
ATOM 1994  C CD2 . TRP A 1 317 ? 9.619   -20.429 -22.880 1.00 79.60  ? 317 TRP A CD2 1 
ATOM 1995  N NE1 . TRP A 1 317 ? 7.985   -21.667 -21.972 1.00 76.93  ? 317 TRP A NE1 1 
ATOM 1996  C CE2 . TRP A 1 317 ? 9.346   -21.563 -22.088 1.00 83.53  ? 317 TRP A CE2 1 
ATOM 1997  C CE3 . TRP A 1 317 ? 10.950  -20.098 -23.153 1.00 89.61  ? 317 TRP A CE3 1 
ATOM 1998  C CZ2 . TRP A 1 317 ? 10.356  -22.368 -21.566 1.00 90.38  ? 317 TRP A CZ2 1 
ATOM 1999  C CZ3 . TRP A 1 317 ? 11.952  -20.901 -22.630 1.00 89.30  ? 317 TRP A CZ3 1 
ATOM 2000  C CH2 . TRP A 1 317 ? 11.650  -22.022 -21.848 1.00 81.71  ? 317 TRP A CH2 1 
ATOM 2001  N N   . ALA A 1 318 ? 5.799   -17.058 -25.816 1.00 83.64  ? 318 ALA A N   1 
ATOM 2002  C CA  . ALA A 1 318 ? 5.315   -15.822 -26.400 1.00 73.82  ? 318 ALA A CA  1 
ATOM 2003  C C   . ALA A 1 318 ? 4.915   -14.841 -25.304 1.00 68.03  ? 318 ALA A C   1 
ATOM 2004  O O   . ALA A 1 318 ? 4.538   -15.257 -24.203 1.00 63.68  ? 318 ALA A O   1 
ATOM 2005  C CB  . ALA A 1 318 ? 4.114   -16.076 -27.320 1.00 75.43  ? 318 ALA A CB  1 
ATOM 2006  N N   . PRO A 1 319 ? 4.986   -13.535 -25.571 1.00 65.98  ? 319 PRO A N   1 
ATOM 2007  C CA  . PRO A 1 319 ? 4.576   -12.555 -24.558 1.00 64.38  ? 319 PRO A CA  1 
ATOM 2008  C C   . PRO A 1 319 ? 3.069   -12.546 -24.361 1.00 58.56  ? 319 PRO A C   1 
ATOM 2009  O O   . PRO A 1 319 ? 2.401   -11.579 -24.733 1.00 57.89  ? 319 PRO A O   1 
ATOM 2010  C CB  . PRO A 1 319 ? 5.070   -11.219 -25.132 1.00 68.86  ? 319 PRO A CB  1 
ATOM 2011  C CG  . PRO A 1 319 ? 5.973   -11.575 -26.272 1.00 61.98  ? 319 PRO A CG  1 
ATOM 2012  C CD  . PRO A 1 319 ? 5.504   -12.887 -26.784 1.00 61.86  ? 319 PRO A CD  1 
ATOM 2013  N N   . GLN A 1 320 ? 2.531   -13.618 -23.775 1.00 61.64  ? 320 GLN A N   1 
ATOM 2014  C CA  . GLN A 1 320 ? 1.083   -13.754 -23.644 1.00 64.58  ? 320 GLN A CA  1 
ATOM 2015  C C   . GLN A 1 320 ? 0.490   -12.587 -22.866 1.00 63.16  ? 320 GLN A C   1 
ATOM 2016  O O   . GLN A 1 320 ? -0.436  -11.916 -23.340 1.00 58.30  ? 320 GLN A O   1 
ATOM 2017  C CB  . GLN A 1 320 ? 0.745   -15.082 -22.969 1.00 65.26  ? 320 GLN A CB  1 
ATOM 2018  C CG  . GLN A 1 320 ? -0.727  -15.444 -23.001 1.00 65.81  ? 320 GLN A CG  1 
ATOM 2019  C CD  . GLN A 1 320 ? -1.009  -16.770 -22.326 1.00 72.29  ? 320 GLN A CD  1 
ATOM 2020  O OE1 . GLN A 1 320 ? -0.381  -17.115 -21.322 1.00 66.78  ? 320 GLN A OE1 1 
ATOM 2021  N NE2 . GLN A 1 320 ? -1.956  -17.526 -22.877 1.00 73.49  ? 320 GLN A NE2 1 
ATOM 2022  N N   . ALA A 1 321 ? 1.018   -12.325 -21.670 1.00 63.49  ? 321 ALA A N   1 
ATOM 2023  C CA  . ALA A 1 321 ? 0.521   -11.207 -20.874 1.00 58.04  ? 321 ALA A CA  1 
ATOM 2024  C C   . ALA A 1 321 ? 0.775   -9.877  -21.572 1.00 59.09  ? 321 ALA A C   1 
ATOM 2025  O O   . ALA A 1 321 ? -0.069  -8.973  -21.527 1.00 61.50  ? 321 ALA A O   1 
ATOM 2026  C CB  . ALA A 1 321 ? 1.167   -11.218 -19.490 1.00 63.41  ? 321 ALA A CB  1 
ATOM 2027  N N   . ARG A 1 322 ? 1.928   -9.740  -22.230 1.00 51.88  ? 322 ARG A N   1 
ATOM 2028  C CA  . ARG A 1 322 ? 2.274   -8.487  -22.894 1.00 54.53  ? 322 ARG A CA  1 
ATOM 2029  C C   . ARG A 1 322 ? 1.496   -8.287  -24.187 1.00 52.40  ? 322 ARG A C   1 
ATOM 2030  O O   . ARG A 1 322 ? 1.283   -7.143  -24.603 1.00 44.86  ? 322 ARG A O   1 
ATOM 2031  C CB  . ARG A 1 322 ? 3.779   -8.441  -23.166 1.00 61.62  ? 322 ARG A CB  1 
ATOM 2032  C CG  . ARG A 1 322 ? 4.626   -8.902  -21.985 1.00 70.42  ? 322 ARG A CG  1 
ATOM 2033  C CD  . ARG A 1 322 ? 6.117   -8.715  -22.235 1.00 68.42  ? 322 ARG A CD  1 
ATOM 2034  N NE  . ARG A 1 322 ? 6.606   -7.437  -21.732 1.00 76.39  ? 322 ARG A NE  1 
ATOM 2035  C CZ  . ARG A 1 322 ? 6.655   -6.316  -22.440 1.00 74.33  ? 322 ARG A CZ  1 
ATOM 2036  N NH1 . ARG A 1 322 ? 6.253   -6.275  -23.700 1.00 69.50  ? 322 ARG A NH1 1 
ATOM 2037  N NH2 . ARG A 1 322 ? 7.122   -5.207  -21.871 1.00 80.51  ? 322 ARG A NH2 1 
ATOM 2038  N N   . ILE A 1 323 ? 1.062   -9.371  -24.835 1.00 52.44  ? 323 ILE A N   1 
ATOM 2039  C CA  . ILE A 1 323 ? 0.232   -9.233  -26.025 1.00 54.35  ? 323 ILE A CA  1 
ATOM 2040  C C   . ILE A 1 323 ? -1.213  -8.943  -25.643 1.00 55.13  ? 323 ILE A C   1 
ATOM 2041  O O   . ILE A 1 323 ? -1.862  -8.073  -26.236 1.00 47.31  ? 323 ILE A O   1 
ATOM 2042  C CB  . ILE A 1 323 ? 0.345   -10.490 -26.909 1.00 55.07  ? 323 ILE A CB  1 
ATOM 2043  C CG1 . ILE A 1 323 ? 1.712   -10.539 -27.590 1.00 53.42  ? 323 ILE A CG1 1 
ATOM 2044  C CG2 . ILE A 1 323 ? -0.765  -10.523 -27.944 1.00 55.64  ? 323 ILE A CG2 1 
ATOM 2045  C CD1 . ILE A 1 323 ? 1.927   -11.780 -28.419 1.00 59.82  ? 323 ILE A CD1 1 
ATOM 2046  N N   . LEU A 1 324 ? -1.742  -9.662  -24.647 1.00 52.64  ? 324 LEU A N   1 
ATOM 2047  C CA  . LEU A 1 324 ? -3.099  -9.390  -24.189 1.00 49.53  ? 324 LEU A CA  1 
ATOM 2048  C C   . LEU A 1 324 ? -3.214  -8.001  -23.578 1.00 47.38  ? 324 LEU A C   1 
ATOM 2049  O O   . LEU A 1 324 ? -4.256  -7.348  -23.707 1.00 53.63  ? 324 LEU A O   1 
ATOM 2050  C CB  . LEU A 1 324 ? -3.540  -10.455 -23.185 1.00 47.20  ? 324 LEU A CB  1 
ATOM 2051  C CG  . LEU A 1 324 ? -3.677  -11.884 -23.713 1.00 46.34  ? 324 LEU A CG  1 
ATOM 2052  C CD1 . LEU A 1 324 ? -4.161  -12.809 -22.608 1.00 44.44  ? 324 LEU A CD1 1 
ATOM 2053  C CD2 . LEU A 1 324 ? -4.616  -11.932 -24.909 1.00 47.56  ? 324 LEU A CD2 1 
ATOM 2054  N N   . GLY A 1 325 ? -2.152  -7.524  -22.920 1.00 48.81  ? 325 GLY A N   1 
ATOM 2055  C CA  . GLY A 1 325 ? -2.164  -6.180  -22.373 1.00 52.40  ? 325 GLY A CA  1 
ATOM 2056  C C   . GLY A 1 325 ? -1.958  -5.087  -23.395 1.00 47.44  ? 325 GLY A C   1 
ATOM 2057  O O   . GLY A 1 325 ? -2.262  -3.925  -23.112 1.00 41.13  ? 325 GLY A O   1 
ATOM 2058  N N   . HIS A 1 326 ? -1.462  -5.429  -24.580 1.00 54.43  ? 326 HIS A N   1 
ATOM 2059  C CA  . HIS A 1 326 ? -1.271  -4.426  -25.618 1.00 58.20  ? 326 HIS A CA  1 
ATOM 2060  C C   . HIS A 1 326 ? -2.617  -3.994  -26.187 1.00 58.29  ? 326 HIS A C   1 
ATOM 2061  O O   . HIS A 1 326 ? -3.551  -4.793  -26.295 1.00 61.59  ? 326 HIS A O   1 
ATOM 2062  C CB  . HIS A 1 326 ? -0.367  -4.970  -26.726 1.00 55.42  ? 326 HIS A CB  1 
ATOM 2063  C CG  . HIS A 1 326 ? 0.151   -3.921  -27.658 1.00 64.23  ? 326 HIS A CG  1 
ATOM 2064  N ND1 . HIS A 1 326 ? -0.463  -3.626  -28.856 1.00 61.35  ? 326 HIS A ND1 1 
ATOM 2065  C CD2 . HIS A 1 326 ? 1.221   -3.097  -27.569 1.00 66.90  ? 326 HIS A CD2 1 
ATOM 2066  C CE1 . HIS A 1 326 ? 0.208   -2.665  -29.467 1.00 57.68  ? 326 HIS A CE1 1 
ATOM 2067  N NE2 . HIS A 1 326 ? 1.233   -2.326  -28.707 1.00 65.17  ? 326 HIS A NE2 1 
ATOM 2068  N N   . SER A 1 327 ? -2.713  -2.714  -26.548 1.00 52.91  ? 327 SER A N   1 
ATOM 2069  C CA  . SER A 1 327 ? -3.993  -2.159  -26.973 1.00 54.32  ? 327 SER A CA  1 
ATOM 2070  C C   . SER A 1 327 ? -4.424  -2.659  -28.346 1.00 60.09  ? 327 SER A C   1 
ATOM 2071  O O   . SER A 1 327 ? -5.603  -2.530  -28.693 1.00 57.69  ? 327 SER A O   1 
ATOM 2072  C CB  . SER A 1 327 ? -3.930  -0.633  -26.976 1.00 64.93  ? 327 SER A CB  1 
ATOM 2073  O OG  . SER A 1 327 ? -2.866  -0.166  -27.789 1.00 78.84  ? 327 SER A OG  1 
ATOM 2074  N N   . SER A 1 328 ? -3.506  -3.220  -29.135 1.00 62.49  ? 328 SER A N   1 
ATOM 2075  C CA  . SER A 1 328 ? -3.844  -3.686  -30.475 1.00 60.95  ? 328 SER A CA  1 
ATOM 2076  C C   . SER A 1 328 ? -4.540  -5.040  -30.479 1.00 57.53  ? 328 SER A C   1 
ATOM 2077  O O   . SER A 1 328 ? -5.047  -5.452  -31.529 1.00 52.27  ? 328 SER A O   1 
ATOM 2078  C CB  . SER A 1 328 ? -2.585  -3.757  -31.342 1.00 57.99  ? 328 SER A CB  1 
ATOM 2079  O OG  . SER A 1 328 ? -2.054  -2.466  -31.573 1.00 64.12  ? 328 SER A OG  1 
ATOM 2080  N N   . THR A 1 329 ? -4.579  -5.737  -29.349 1.00 54.96  ? 329 THR A N   1 
ATOM 2081  C CA  . THR A 1 329 ? -5.198  -7.050  -29.279 1.00 48.64  ? 329 THR A CA  1 
ATOM 2082  C C   . THR A 1 329 ? -6.660  -6.913  -28.874 1.00 52.03  ? 329 THR A C   1 
ATOM 2083  O O   . THR A 1 329 ? -6.985  -6.245  -27.886 1.00 55.30  ? 329 THR A O   1 
ATOM 2084  C CB  . THR A 1 329 ? -4.456  -7.950  -28.291 1.00 52.22  ? 329 THR A CB  1 
ATOM 2085  O OG1 . THR A 1 329 ? -3.048  -7.866  -28.538 1.00 62.82  ? 329 THR A OG1 1 
ATOM 2086  C CG2 . THR A 1 329 ? -4.901  -9.394  -28.451 1.00 52.23  ? 329 THR A CG2 1 
ATOM 2087  N N   . GLY A 1 330 ? -7.535  -7.541  -29.651 1.00 46.42  ? 330 GLY A N   1 
ATOM 2088  C CA  . GLY A 1 330 ? -8.956  -7.538  -29.371 1.00 47.46  ? 330 GLY A CA  1 
ATOM 2089  C C   . GLY A 1 330 ? -9.588  -8.911  -29.484 1.00 54.03  ? 330 GLY A C   1 
ATOM 2090  O O   . GLY A 1 330 ? -10.814 -9.032  -29.596 1.00 48.36  ? 330 GLY A O   1 
ATOM 2091  N N   . GLY A 1 331 ? -8.757  -9.954  -29.455 1.00 54.30  ? 331 GLY A N   1 
ATOM 2092  C CA  . GLY A 1 331 ? -9.216  -11.328 -29.547 1.00 50.33  ? 331 GLY A CA  1 
ATOM 2093  C C   . GLY A 1 331 ? -8.181  -12.329 -29.071 1.00 50.60  ? 331 GLY A C   1 
ATOM 2094  O O   . GLY A 1 331 ? -6.977  -12.131 -29.271 1.00 48.19  ? 331 GLY A O   1 
ATOM 2095  N N   . PHE A 1 332 ? -8.637  -13.411 -28.435 1.00 46.94  ? 332 PHE A N   1 
ATOM 2096  C CA  . PHE A 1 332 ? -7.733  -14.414 -27.862 1.00 52.54  ? 332 PHE A CA  1 
ATOM 2097  C C   . PHE A 1 332 ? -8.305  -15.800 -28.143 1.00 48.45  ? 332 PHE A C   1 
ATOM 2098  O O   . PHE A 1 332 ? -9.184  -16.271 -27.416 1.00 56.39  ? 332 PHE A O   1 
ATOM 2099  C CB  . PHE A 1 332 ? -7.539  -14.186 -26.364 1.00 48.91  ? 332 PHE A CB  1 
ATOM 2100  C CG  . PHE A 1 332 ? -6.551  -15.130 -25.700 1.00 49.29  ? 332 PHE A CG  1 
ATOM 2101  C CD1 . PHE A 1 332 ? -5.715  -15.955 -26.443 1.00 53.06  ? 332 PHE A CD1 1 
ATOM 2102  C CD2 . PHE A 1 332 ? -6.468  -15.187 -24.318 1.00 53.50  ? 332 PHE A CD2 1 
ATOM 2103  C CE1 . PHE A 1 332 ? -4.820  -16.820 -25.812 1.00 58.80  ? 332 PHE A CE1 1 
ATOM 2104  C CE2 . PHE A 1 332 ? -5.575  -16.048 -23.685 1.00 54.30  ? 332 PHE A CE2 1 
ATOM 2105  C CZ  . PHE A 1 332 ? -4.752  -16.861 -24.431 1.00 48.25  ? 332 PHE A CZ  1 
ATOM 2106  N N   . VAL A 1 333 ? -7.793  -16.454 -29.181 1.00 46.15  ? 333 VAL A N   1 
ATOM 2107  C CA  . VAL A 1 333 ? -8.141  -17.842 -29.471 1.00 44.86  ? 333 VAL A CA  1 
ATOM 2108  C C   . VAL A 1 333 ? -7.351  -18.723 -28.507 1.00 49.68  ? 333 VAL A C   1 
ATOM 2109  O O   . VAL A 1 333 ? -6.124  -18.811 -28.600 1.00 51.05  ? 333 VAL A O   1 
ATOM 2110  C CB  . VAL A 1 333 ? -7.844  -18.211 -30.928 1.00 47.34  ? 333 VAL A CB  1 
ATOM 2111  C CG1 . VAL A 1 333 ? -8.175  -19.675 -31.183 1.00 45.30  ? 333 VAL A CG1 1 
ATOM 2112  C CG2 . VAL A 1 333 ? -8.631  -17.318 -31.871 1.00 48.46  ? 333 VAL A CG2 1 
ATOM 2113  N N   . SER A 1 334 ? -8.047  -19.378 -27.582 1.00 43.98  ? 334 SER A N   1 
ATOM 2114  C CA  . SER A 1 334 ? -7.383  -20.072 -26.492 1.00 50.09  ? 334 SER A CA  1 
ATOM 2115  C C   . SER A 1 334 ? -7.968  -21.464 -26.298 1.00 52.18  ? 334 SER A C   1 
ATOM 2116  O O   . SER A 1 334 ? -9.107  -21.745 -26.675 1.00 53.95  ? 334 SER A O   1 
ATOM 2117  C CB  . SER A 1 334 ? -7.492  -19.280 -25.182 1.00 50.08  ? 334 SER A CB  1 
ATOM 2118  O OG  . SER A 1 334 ? -6.989  -20.031 -24.093 1.00 54.84  ? 334 SER A OG  1 
ATOM 2119  N N   . HIS A 1 335 ? -7.160  -22.336 -25.696 1.00 54.13  ? 335 HIS A N   1 
ATOM 2120  C CA  . HIS A 1 335 ? -7.619  -23.659 -25.289 1.00 49.95  ? 335 HIS A CA  1 
ATOM 2121  C C   . HIS A 1 335 ? -8.350  -23.636 -23.957 1.00 51.63  ? 335 HIS A C   1 
ATOM 2122  O O   . HIS A 1 335 ? -8.711  -24.705 -23.451 1.00 54.21  ? 335 HIS A O   1 
ATOM 2123  C CB  . HIS A 1 335 ? -6.437  -24.631 -25.216 1.00 61.35  ? 335 HIS A CB  1 
ATOM 2124  C CG  . HIS A 1 335 ? -5.554  -24.427 -24.022 1.00 63.75  ? 335 HIS A CG  1 
ATOM 2125  N ND1 . HIS A 1 335 ? -4.827  -23.273 -23.822 1.00 62.91  ? 335 HIS A ND1 1 
ATOM 2126  C CD2 . HIS A 1 335 ? -5.274  -25.237 -22.973 1.00 63.36  ? 335 HIS A CD2 1 
ATOM 2127  C CE1 . HIS A 1 335 ? -4.143  -23.378 -22.695 1.00 56.40  ? 335 HIS A CE1 1 
ATOM 2128  N NE2 . HIS A 1 335 ? -4.394  -24.560 -22.161 1.00 59.51  ? 335 HIS A NE2 1 
ATOM 2129  N N   . CYS A 1 336 ? -8.561  -22.449 -23.381 1.00 52.85  ? 336 CYS A N   1 
ATOM 2130  C CA  . CYS A 1 336 ? -9.369  -22.258 -22.173 1.00 52.23  ? 336 CYS A CA  1 
ATOM 2131  C C   . CYS A 1 336 ? -8.707  -22.870 -20.938 1.00 53.32  ? 336 CYS A C   1 
ATOM 2132  O O   . CYS A 1 336 ? -9.336  -23.584 -20.160 1.00 48.87  ? 336 CYS A O   1 
ATOM 2133  C CB  . CYS A 1 336 ? -10.789 -22.799 -22.362 1.00 53.99  ? 336 CYS A CB  1 
ATOM 2134  S SG  . CYS A 1 336 ? -11.766 -21.844 -23.523 1.00 57.63  ? 336 CYS A SG  1 
ATOM 2135  N N   . GLY A 1 337 ? -7.421  -22.582 -20.766 1.00 49.30  ? 337 GLY A N   1 
ATOM 2136  C CA  . GLY A 1 337 ? -6.801  -22.781 -19.473 1.00 39.76  ? 337 GLY A CA  1 
ATOM 2137  C C   . GLY A 1 337 ? -7.254  -21.716 -18.492 1.00 38.46  ? 337 GLY A C   1 
ATOM 2138  O O   . GLY A 1 337 ? -7.595  -20.594 -18.870 1.00 33.70  ? 337 GLY A O   1 
ATOM 2139  N N   . TRP A 1 338 ? -7.271  -22.074 -17.209 1.00 39.37  ? 338 TRP A N   1 
ATOM 2140  C CA  . TRP A 1 338 ? -7.797  -21.151 -16.208 1.00 34.38  ? 338 TRP A CA  1 
ATOM 2141  C C   . TRP A 1 338 ? -6.951  -19.889 -16.123 1.00 34.66  ? 338 TRP A C   1 
ATOM 2142  O O   . TRP A 1 338 ? -7.481  -18.772 -16.095 1.00 42.13  ? 338 TRP A O   1 
ATOM 2143  C CB  . TRP A 1 338 ? -7.894  -21.838 -14.847 1.00 36.58  ? 338 TRP A CB  1 
ATOM 2144  C CG  . TRP A 1 338 ? -8.631  -21.019 -13.828 1.00 34.30  ? 338 TRP A CG  1 
ATOM 2145  C CD1 . TRP A 1 338 ? -8.172  -20.628 -12.605 1.00 30.11  ? 338 TRP A CD1 1 
ATOM 2146  C CD2 . TRP A 1 338 ? -9.954  -20.476 -13.950 1.00 34.35  ? 338 TRP A CD2 1 
ATOM 2147  N NE1 . TRP A 1 338 ? -9.127  -19.890 -11.953 1.00 36.84  ? 338 TRP A NE1 1 
ATOM 2148  C CE2 . TRP A 1 338 ? -10.230 -19.780 -12.757 1.00 36.37  ? 338 TRP A CE2 1 
ATOM 2149  C CE3 . TRP A 1 338 ? -10.931 -20.518 -14.952 1.00 34.88  ? 338 TRP A CE3 1 
ATOM 2150  C CZ2 . TRP A 1 338 ? -11.443 -19.129 -12.538 1.00 40.94  ? 338 TRP A CZ2 1 
ATOM 2151  C CZ3 . TRP A 1 338 ? -12.131 -19.870 -14.732 1.00 39.80  ? 338 TRP A CZ3 1 
ATOM 2152  C CH2 . TRP A 1 338 ? -12.378 -19.186 -13.536 1.00 34.89  ? 338 TRP A CH2 1 
ATOM 2153  N N   . SER A 1 339 ? -5.625  -20.039 -16.079 1.00 39.50  ? 339 SER A N   1 
ATOM 2154  C CA  . SER A 1 339 ? -4.761  -18.860 -16.067 1.00 42.23  ? 339 SER A CA  1 
ATOM 2155  C C   . SER A 1 339 ? -4.891  -18.074 -17.364 1.00 33.79  ? 339 SER A C   1 
ATOM 2156  O O   . SER A 1 339 ? -4.831  -16.839 -17.358 1.00 36.43  ? 339 SER A O   1 
ATOM 2157  C CB  . SER A 1 339 ? -3.308  -19.271 -15.828 1.00 34.18  ? 339 SER A CB  1 
ATOM 2158  O OG  . SER A 1 339 ? -3.140  -19.813 -14.531 1.00 26.71  ? 339 SER A OG  1 
ATOM 2159  N N   . SER A 1 340 ? -5.090  -18.772 -18.483 1.00 33.19  ? 340 SER A N   1 
ATOM 2160  C CA  . SER A 1 340 ? -5.257  -18.091 -19.762 1.00 50.25  ? 340 SER A CA  1 
ATOM 2161  C C   . SER A 1 340 ? -6.523  -17.243 -19.773 1.00 50.32  ? 340 SER A C   1 
ATOM 2162  O O   . SER A 1 340 ? -6.503  -16.084 -20.205 1.00 41.72  ? 340 SER A O   1 
ATOM 2163  C CB  . SER A 1 340 ? -5.275  -19.113 -20.896 1.00 47.56  ? 340 SER A CB  1 
ATOM 2164  O OG  . SER A 1 340 ? -4.061  -19.843 -20.929 1.00 55.75  ? 340 SER A OG  1 
ATOM 2165  N N   . ILE A 1 341 ? -7.637  -17.800 -19.288 1.00 38.18  ? 341 ILE A N   1 
ATOM 2166  C CA  . ILE A 1 341 ? -8.887  -17.046 -19.247 1.00 38.41  ? 341 ILE A CA  1 
ATOM 2167  C C   . ILE A 1 341 ? -8.785  -15.888 -18.261 1.00 37.13  ? 341 ILE A C   1 
ATOM 2168  O O   . ILE A 1 341 ? -9.283  -14.785 -18.525 1.00 46.54  ? 341 ILE A O   1 
ATOM 2169  C CB  . ILE A 1 341 ? -10.058 -17.985 -18.909 1.00 47.76  ? 341 ILE A CB  1 
ATOM 2170  C CG1 . ILE A 1 341 ? -10.304 -18.952 -20.071 1.00 46.31  ? 341 ILE A CG1 1 
ATOM 2171  C CG2 . ILE A 1 341 ? -11.316 -17.189 -18.591 1.00 46.27  ? 341 ILE A CG2 1 
ATOM 2172  C CD1 . ILE A 1 341 ? -11.485 -19.872 -19.863 1.00 47.60  ? 341 ILE A CD1 1 
ATOM 2173  N N   . ALA A 1 342 ? -8.135  -16.111 -17.118 1.00 37.46  ? 342 ALA A N   1 
ATOM 2174  C CA  . ALA A 1 342 ? -7.946  -15.027 -16.159 1.00 46.98  ? 342 ALA A CA  1 
ATOM 2175  C C   . ALA A 1 342 ? -7.143  -13.885 -16.772 1.00 44.98  ? 342 ALA A C   1 
ATOM 2176  O O   . ALA A 1 342 ? -7.506  -12.713 -16.623 1.00 44.58  ? 342 ALA A O   1 
ATOM 2177  C CB  . ALA A 1 342 ? -7.264  -15.553 -14.895 1.00 37.84  ? 342 ALA A CB  1 
ATOM 2178  N N   . GLU A 1 343 ? -6.050  -14.209 -17.468 1.00 48.84  ? 343 GLU A N   1 
ATOM 2179  C CA  . GLU A 1 343 ? -5.254  -13.166 -18.113 1.00 47.90  ? 343 GLU A CA  1 
ATOM 2180  C C   . GLU A 1 343 ? -6.041  -12.465 -19.211 1.00 42.75  ? 343 GLU A C   1 
ATOM 2181  O O   . GLU A 1 343 ? -5.926  -11.247 -19.387 1.00 46.78  ? 343 GLU A O   1 
ATOM 2182  C CB  . GLU A 1 343 ? -3.965  -13.757 -18.682 1.00 47.42  ? 343 GLU A CB  1 
ATOM 2183  C CG  . GLU A 1 343 ? -2.902  -14.065 -17.650 1.00 52.86  ? 343 GLU A CG  1 
ATOM 2184  C CD  . GLU A 1 343 ? -1.579  -14.425 -18.291 1.00 63.31  ? 343 GLU A CD  1 
ATOM 2185  O OE1 . GLU A 1 343 ? -1.588  -14.836 -19.470 1.00 52.87  ? 343 GLU A OE1 1 
ATOM 2186  O OE2 . GLU A 1 343 ? -0.532  -14.287 -17.625 1.00 64.27  ? 343 GLU A OE2 1 
ATOM 2187  N N   . SER A 1 344 ? -6.843  -13.219 -19.967 1.00 45.45  ? 344 SER A N   1 
ATOM 2188  C CA  . SER A 1 344 ? -7.655  -12.605 -21.012 1.00 50.84  ? 344 SER A CA  1 
ATOM 2189  C C   . SER A 1 344 ? -8.690  -11.657 -20.427 1.00 46.43  ? 344 SER A C   1 
ATOM 2190  O O   . SER A 1 344 ? -9.033  -10.648 -21.055 1.00 49.88  ? 344 SER A O   1 
ATOM 2191  C CB  . SER A 1 344 ? -8.340  -13.680 -21.851 1.00 49.13  ? 344 SER A CB  1 
ATOM 2192  O OG  . SER A 1 344 ? -8.960  -13.115 -22.993 1.00 57.07  ? 344 SER A OG  1 
ATOM 2193  N N   . MET A 1 345 ? -9.201  -11.956 -19.236 1.00 42.67  ? 345 MET A N   1 
ATOM 2194  C CA  . MET A 1 345 ? -10.212 -11.094 -18.636 1.00 48.30  ? 345 MET A CA  1 
ATOM 2195  C C   . MET A 1 345 ? -9.618  -9.920  -17.869 1.00 48.07  ? 345 MET A C   1 
ATOM 2196  O O   . MET A 1 345 ? -10.283 -8.886  -17.732 1.00 47.18  ? 345 MET A O   1 
ATOM 2197  C CB  . MET A 1 345 ? -11.124 -11.910 -17.716 1.00 48.16  ? 345 MET A CB  1 
ATOM 2198  C CG  . MET A 1 345 ? -11.935 -12.954 -18.458 1.00 43.46  ? 345 MET A CG  1 
ATOM 2199  S SD  . MET A 1 345 ? -13.334 -13.538 -17.495 1.00 71.83  ? 345 MET A SD  1 
ATOM 2200  C CE  . MET A 1 345 ? -14.256 -12.013 -17.306 1.00 54.02  ? 345 MET A CE  1 
ATOM 2201  N N   . LYS A 1 346 ? -8.385  -10.041 -17.370 1.00 48.43  ? 346 LYS A N   1 
ATOM 2202  C CA  . LYS A 1 346 ? -7.766  -8.903  -16.701 1.00 49.34  ? 346 LYS A CA  1 
ATOM 2203  C C   . LYS A 1 346 ? -7.413  -7.789  -17.678 1.00 53.62  ? 346 LYS A C   1 
ATOM 2204  O O   . LYS A 1 346 ? -7.299  -6.630  -17.265 1.00 53.30  ? 346 LYS A O   1 
ATOM 2205  C CB  . LYS A 1 346 ? -6.512  -9.337  -15.937 1.00 44.13  ? 346 LYS A CB  1 
ATOM 2206  C CG  . LYS A 1 346 ? -5.998  -8.288  -14.951 1.00 50.07  ? 346 LYS A CG  1 
ATOM 2207  C CD  . LYS A 1 346 ? -4.550  -8.534  -14.564 1.00 57.89  ? 346 LYS A CD  1 
ATOM 2208  C CE  . LYS A 1 346 ? -4.045  -7.460  -13.612 1.00 66.83  ? 346 LYS A CE  1 
ATOM 2209  N NZ  . LYS A 1 346 ? -4.170  -6.096  -14.199 1.00 65.18  ? 346 LYS A NZ  1 
ATOM 2210  N N   . PHE A 1 347 ? -7.254  -8.107  -18.963 1.00 50.82  ? 347 PHE A N   1 
ATOM 2211  C CA  . PHE A 1 347 ? -6.913  -7.119  -19.975 1.00 53.12  ? 347 PHE A CA  1 
ATOM 2212  C C   . PHE A 1 347 ? -8.065  -6.839  -20.936 1.00 45.53  ? 347 PHE A C   1 
ATOM 2213  O O   . PHE A 1 347 ? -7.865  -6.146  -21.940 1.00 51.35  ? 347 PHE A O   1 
ATOM 2214  C CB  . PHE A 1 347 ? -5.669  -7.565  -20.748 1.00 51.05  ? 347 PHE A CB  1 
ATOM 2215  C CG  . PHE A 1 347 ? -4.449  -7.727  -19.886 1.00 50.58  ? 347 PHE A CG  1 
ATOM 2216  C CD1 . PHE A 1 347 ? -3.836  -6.623  -19.314 1.00 53.92  ? 347 PHE A CD1 1 
ATOM 2217  C CD2 . PHE A 1 347 ? -3.910  -8.980  -19.652 1.00 49.75  ? 347 PHE A CD2 1 
ATOM 2218  C CE1 . PHE A 1 347 ? -2.712  -6.768  -18.522 1.00 62.19  ? 347 PHE A CE1 1 
ATOM 2219  C CE2 . PHE A 1 347 ? -2.785  -9.131  -18.859 1.00 47.10  ? 347 PHE A CE2 1 
ATOM 2220  C CZ  . PHE A 1 347 ? -2.188  -8.023  -18.294 1.00 59.63  ? 347 PHE A CZ  1 
ATOM 2221  N N   . GLY A 1 348 ? -9.257  -7.360  -20.657 1.00 40.58  ? 348 GLY A N   1 
ATOM 2222  C CA  . GLY A 1 348 ? -10.424 -7.050  -21.465 1.00 42.67  ? 348 GLY A CA  1 
ATOM 2223  C C   . GLY A 1 348 ? -10.411 -7.609  -22.869 1.00 42.70  ? 348 GLY A C   1 
ATOM 2224  O O   . GLY A 1 348 ? -11.040 -7.031  -23.762 1.00 49.12  ? 348 GLY A O   1 
ATOM 2225  N N   . VAL A 1 349 ? -9.717  -8.716  -23.094 1.00 40.89  ? 349 VAL A N   1 
ATOM 2226  C CA  . VAL A 1 349 ? -9.639  -9.356  -24.403 1.00 44.50  ? 349 VAL A CA  1 
ATOM 2227  C C   . VAL A 1 349 ? -10.670 -10.478 -24.442 1.00 47.04  ? 349 VAL A C   1 
ATOM 2228  O O   . VAL A 1 349 ? -10.548 -11.438 -23.666 1.00 43.75  ? 349 VAL A O   1 
ATOM 2229  C CB  . VAL A 1 349 ? -8.227  -9.895  -24.680 1.00 49.55  ? 349 VAL A CB  1 
ATOM 2230  C CG1 . VAL A 1 349 ? -8.171  -10.580 -26.037 1.00 51.67  ? 349 VAL A CG1 1 
ATOM 2231  C CG2 . VAL A 1 349 ? -7.202  -8.772  -24.596 1.00 37.16  ? 349 VAL A CG2 1 
ATOM 2232  N N   . PRO A 1 350 ? -11.683 -10.407 -25.308 1.00 47.54  ? 350 PRO A N   1 
ATOM 2233  C CA  . PRO A 1 350 ? -12.669 -11.492 -25.380 1.00 44.00  ? 350 PRO A CA  1 
ATOM 2234  C C   . PRO A 1 350 ? -12.038 -12.797 -25.845 1.00 47.19  ? 350 PRO A C   1 
ATOM 2235  O O   . PRO A 1 350 ? -10.964 -12.822 -26.446 1.00 56.32  ? 350 PRO A O   1 
ATOM 2236  C CB  . PRO A 1 350 ? -13.698 -10.975 -26.392 1.00 44.73  ? 350 PRO A CB  1 
ATOM 2237  C CG  . PRO A 1 350 ? -12.968 -9.949  -27.188 1.00 48.10  ? 350 PRO A CG  1 
ATOM 2238  C CD  . PRO A 1 350 ? -12.000 -9.309  -26.236 1.00 49.00  ? 350 PRO A CD  1 
ATOM 2239  N N   . VAL A 1 351 ? -12.732 -13.896 -25.559 1.00 45.87  ? 351 VAL A N   1 
ATOM 2240  C CA  . VAL A 1 351 ? -12.168 -15.239 -25.664 1.00 51.32  ? 351 VAL A CA  1 
ATOM 2241  C C   . VAL A 1 351 ? -12.834 -15.991 -26.809 1.00 53.38  ? 351 VAL A C   1 
ATOM 2242  O O   . VAL A 1 351 ? -14.063 -15.972 -26.951 1.00 56.06  ? 351 VAL A O   1 
ATOM 2243  C CB  . VAL A 1 351 ? -12.321 -16.014 -24.346 1.00 47.86  ? 351 VAL A CB  1 
ATOM 2244  C CG1 . VAL A 1 351 ? -11.637 -17.369 -24.444 1.00 45.76  ? 351 VAL A CG1 1 
ATOM 2245  C CG2 . VAL A 1 351 ? -11.757 -15.207 -23.187 1.00 44.49  ? 351 VAL A CG2 1 
ATOM 2246  N N   . ILE A 1 352 ? -12.014 -16.650 -27.624 1.00 52.01  ? 352 ILE A N   1 
ATOM 2247  C CA  . ILE A 1 352 ? -12.463 -17.610 -28.623 1.00 47.08  ? 352 ILE A CA  1 
ATOM 2248  C C   . ILE A 1 352 ? -12.138 -18.985 -28.050 1.00 51.43  ? 352 ILE A C   1 
ATOM 2249  O O   . ILE A 1 352 ? -10.973 -19.403 -28.022 1.00 52.62  ? 352 ILE A O   1 
ATOM 2250  C CB  . ILE A 1 352 ? -11.780 -17.383 -29.975 1.00 52.48  ? 352 ILE A CB  1 
ATOM 2251  C CG1 . ILE A 1 352 ? -11.742 -15.893 -30.318 1.00 50.07  ? 352 ILE A CG1 1 
ATOM 2252  C CG2 . ILE A 1 352 ? -12.485 -18.168 -31.069 1.00 53.15  ? 352 ILE A CG2 1 
ATOM 2253  C CD1 . ILE A 1 352 ? -13.102 -15.282 -30.511 1.00 59.00  ? 352 ILE A CD1 1 
ATOM 2254  N N   . ALA A 1 353 ? -13.164 -19.686 -27.582 1.00 55.07  ? 353 ALA A N   1 
ATOM 2255  C CA  . ALA A 1 353 ? -12.973 -20.940 -26.873 1.00 49.97  ? 353 ALA A CA  1 
ATOM 2256  C C   . ALA A 1 353 ? -12.739 -22.081 -27.853 1.00 55.69  ? 353 ALA A C   1 
ATOM 2257  O O   . ALA A 1 353 ? -13.544 -22.313 -28.762 1.00 60.82  ? 353 ALA A O   1 
ATOM 2258  C CB  . ALA A 1 353 ? -14.182 -21.243 -25.989 1.00 58.94  ? 353 ALA A CB  1 
ATOM 2259  N N   . MET A 1 354 ? -11.623 -22.799 -27.664 1.00 56.71  ? 354 MET A N   1 
ATOM 2260  C CA  . MET A 1 354 ? -11.284 -23.978 -28.449 1.00 63.96  ? 354 MET A CA  1 
ATOM 2261  C C   . MET A 1 354 ? -10.687 -25.015 -27.489 1.00 63.40  ? 354 MET A C   1 
ATOM 2262  O O   . MET A 1 354 ? -9.507  -25.355 -27.545 1.00 67.30  ? 354 MET A O   1 
ATOM 2263  C CB  . MET A 1 354 ? -10.326 -23.641 -29.594 1.00 60.13  ? 354 MET A CB  1 
ATOM 2264  C CG  . MET A 1 354 ? -10.968 -22.842 -30.721 1.00 62.07  ? 354 MET A CG  1 
ATOM 2265  S SD  . MET A 1 354 ? -9.900  -22.610 -32.157 1.00 71.26  ? 354 MET A SD  1 
ATOM 2266  C CE  . MET A 1 354 ? -9.392  -24.298 -32.479 1.00 68.46  ? 354 MET A CE  1 
ATOM 2267  N N   . ALA A 1 355 ? -11.521 -25.521 -26.586 1.00 56.18  ? 355 ALA A N   1 
ATOM 2268  C CA  . ALA A 1 355 ? -11.093 -26.496 -25.598 1.00 61.60  ? 355 ALA A CA  1 
ATOM 2269  C C   . ALA A 1 355 ? -11.104 -27.903 -26.191 1.00 56.37  ? 355 ALA A C   1 
ATOM 2270  O O   . ALA A 1 355 ? -11.586 -28.136 -27.302 1.00 68.50  ? 355 ALA A O   1 
ATOM 2271  C CB  . ALA A 1 355 ? -11.991 -26.432 -24.366 1.00 58.82  ? 355 ALA A CB  1 
ATOM 2272  N N   . ARG A 1 356 ? -10.557 -28.855 -25.432 1.00 58.29  ? 356 ARG A N   1 
ATOM 2273  C CA  . ARG A 1 356 ? -10.552 -30.242 -25.887 1.00 69.66  ? 356 ARG A CA  1 
ATOM 2274  C C   . ARG A 1 356 ? -10.602 -31.233 -24.729 1.00 74.58  ? 356 ARG A C   1 
ATOM 2275  O O   . ARG A 1 356 ? -11.445 -32.137 -24.724 1.00 81.42  ? 356 ARG A O   1 
ATOM 2276  C CB  . ARG A 1 356 ? -9.324  -30.517 -26.760 1.00 79.36  ? 356 ARG A CB  1 
ATOM 2277  C CG  . ARG A 1 356 ? -9.655  -31.283 -28.036 1.00 82.32  ? 356 ARG A CG  1 
ATOM 2278  C CD  . ARG A 1 356 ? -8.408  -31.673 -28.817 1.00 79.99  ? 356 ARG A CD  1 
ATOM 2279  N NE  . ARG A 1 356 ? -7.746  -32.841 -28.244 1.00 86.74  ? 356 ARG A NE  1 
ATOM 2280  C CZ  . ARG A 1 356 ? -8.090  -34.097 -28.503 1.00 86.30  ? 356 ARG A CZ  1 
ATOM 2281  N NH1 . ARG A 1 356 ? -9.098  -34.385 -29.310 1.00 96.65  ? 356 ARG A NH1 1 
ATOM 2282  N NH2 . ARG A 1 356 ? -7.408  -35.087 -27.936 1.00 83.43  ? 356 ARG A NH2 1 
ATOM 2283  N N   . HIS A 1 357 ? -9.712  -31.088 -23.751 1.00 72.54  ? 357 HIS A N   1 
ATOM 2284  C CA  . HIS A 1 357 ? -9.587  -32.060 -22.675 1.00 75.39  ? 357 HIS A CA  1 
ATOM 2285  C C   . HIS A 1 357 ? -9.538  -31.351 -21.326 1.00 74.51  ? 357 HIS A C   1 
ATOM 2286  O O   . HIS A 1 357 ? -9.478  -30.122 -21.242 1.00 75.07  ? 357 HIS A O   1 
ATOM 2287  C CB  . HIS A 1 357 ? -8.345  -32.944 -22.863 1.00 81.02  ? 357 HIS A CB  1 
ATOM 2288  C CG  . HIS A 1 357 ? -7.075  -32.171 -23.032 1.00 83.89  ? 357 HIS A CG  1 
ATOM 2289  N ND1 . HIS A 1 357 ? -6.242  -31.865 -21.976 1.00 89.39  ? 357 HIS A ND1 1 
ATOM 2290  C CD2 . HIS A 1 357 ? -6.489  -31.644 -24.136 1.00 87.40  ? 357 HIS A CD2 1 
ATOM 2291  C CE1 . HIS A 1 357 ? -5.202  -31.183 -22.419 1.00 93.72  ? 357 HIS A CE1 1 
ATOM 2292  N NE2 . HIS A 1 357 ? -5.328  -31.036 -23.726 1.00 91.86  ? 357 HIS A NE2 1 
ATOM 2293  N N   . LEU A 1 358 ? -9.571  -32.156 -20.266 1.00 80.00  ? 358 LEU A N   1 
ATOM 2294  C CA  . LEU A 1 358 ? -9.536  -31.688 -18.875 1.00 69.44  ? 358 LEU A CA  1 
ATOM 2295  C C   . LEU A 1 358 ? -10.758 -30.798 -18.628 1.00 65.61  ? 358 LEU A C   1 
ATOM 2296  O O   . LEU A 1 358 ? -11.804 -30.968 -19.266 1.00 67.20  ? 358 LEU A O   1 
ATOM 2297  C CB  . LEU A 1 358 ? -8.200  -31.027 -18.580 1.00 67.84  ? 358 LEU A CB  1 
ATOM 2298  C CG  . LEU A 1 358 ? -6.972  -31.934 -18.666 1.00 78.61  ? 358 LEU A CG  1 
ATOM 2299  C CD1 . LEU A 1 358 ? -5.717  -31.202 -18.210 1.00 79.64  ? 358 LEU A CD1 1 
ATOM 2300  C CD2 . LEU A 1 358 ? -7.191  -33.196 -17.850 1.00 77.01  ? 358 LEU A CD2 1 
ATOM 2301  N N   . ASP A 1 359 ? -10.640 -29.852 -17.701 1.00 62.08  ? 359 ASP A N   1 
ATOM 2302  C CA  . ASP A 1 359 ? -11.720 -28.938 -17.353 1.00 58.29  ? 359 ASP A CA  1 
ATOM 2303  C C   . ASP A 1 359 ? -11.821 -27.753 -18.303 1.00 51.25  ? 359 ASP A C   1 
ATOM 2304  O O   . ASP A 1 359 ? -12.587 -26.823 -18.030 1.00 48.20  ? 359 ASP A O   1 
ATOM 2305  C CB  . ASP A 1 359 ? -11.531 -28.430 -15.923 1.00 52.89  ? 359 ASP A CB  1 
ATOM 2306  C CG  . ASP A 1 359 ? -10.269 -27.601 -15.765 1.00 63.90  ? 359 ASP A CG  1 
ATOM 2307  O OD1 . ASP A 1 359 ? -9.301  -27.836 -16.526 1.00 58.27  ? 359 ASP A OD1 1 
ATOM 2308  O OD2 . ASP A 1 359 ? -10.248 -26.708 -14.889 1.00 68.98  ? 359 ASP A OD2 1 
ATOM 2309  N N   . GLN A 1 360 ? -11.066 -27.773 -19.397 1.00 46.86  ? 360 GLN A N   1 
ATOM 2310  C CA  . GLN A 1 360 ? -11.079 -26.651 -20.330 1.00 46.57  ? 360 GLN A CA  1 
ATOM 2311  C C   . GLN A 1 360 ? -12.445 -26.402 -20.963 1.00 48.57  ? 360 GLN A C   1 
ATOM 2312  O O   . GLN A 1 360 ? -12.809 -25.222 -21.113 1.00 46.20  ? 360 GLN A O   1 
ATOM 2313  C CB  . GLN A 1 360 ? -10.007 -26.869 -21.406 1.00 55.08  ? 360 GLN A CB  1 
ATOM 2314  C CG  . GLN A 1 360 ? -8.601  -27.046 -20.851 1.00 61.46  ? 360 GLN A CG  1 
ATOM 2315  C CD  . GLN A 1 360 ? -7.629  -27.574 -21.885 1.00 70.45  ? 360 GLN A CD  1 
ATOM 2316  O OE1 . GLN A 1 360 ? -7.906  -27.548 -23.086 1.00 61.71  ? 360 GLN A OE1 1 
ATOM 2317  N NE2 . GLN A 1 360 ? -6.484  -28.061 -21.426 1.00 78.96  ? 360 GLN A NE2 1 
ATOM 2318  N N   . PRO A 1 361 ? -13.224 -27.412 -21.372 1.00 55.32  ? 361 PRO A N   1 
ATOM 2319  C CA  . PRO A 1 361 ? -14.585 -27.101 -21.850 1.00 47.20  ? 361 PRO A CA  1 
ATOM 2320  C C   . PRO A 1 361 ? -15.427 -26.384 -20.807 1.00 55.99  ? 361 PRO A C   1 
ATOM 2321  O O   . PRO A 1 361 ? -16.017 -25.337 -21.110 1.00 53.31  ? 361 PRO A O   1 
ATOM 2322  C CB  . PRO A 1 361 ? -15.147 -28.483 -22.208 1.00 47.54  ? 361 PRO A CB  1 
ATOM 2323  C CG  . PRO A 1 361 ? -13.953 -29.289 -22.548 1.00 48.89  ? 361 PRO A CG  1 
ATOM 2324  C CD  . PRO A 1 361 ? -12.890 -28.833 -21.591 1.00 59.91  ? 361 PRO A CD  1 
ATOM 2325  N N   . LEU A 1 362 ? -15.478 -26.907 -19.576 1.00 56.59  ? 362 LEU A N   1 
ATOM 2326  C CA  . LEU A 1 362 ? -16.249 -26.252 -18.521 1.00 55.82  ? 362 LEU A CA  1 
ATOM 2327  C C   . LEU A 1 362 ? -15.821 -24.802 -18.343 1.00 53.34  ? 362 LEU A C   1 
ATOM 2328  O O   . LEU A 1 362 ? -16.663 -23.922 -18.134 1.00 49.90  ? 362 LEU A O   1 
ATOM 2329  C CB  . LEU A 1 362 ? -16.108 -27.012 -17.200 1.00 55.87  ? 362 LEU A CB  1 
ATOM 2330  C CG  . LEU A 1 362 ? -16.663 -28.435 -17.095 1.00 53.62  ? 362 LEU A CG  1 
ATOM 2331  C CD1 . LEU A 1 362 ? -18.015 -28.555 -17.785 1.00 44.66  ? 362 LEU A CD1 1 
ATOM 2332  C CD2 . LEU A 1 362 ? -15.669 -29.463 -17.634 1.00 57.68  ? 362 LEU A CD2 1 
ATOM 2333  N N   . ASN A 1 363 ? -14.516 -24.533 -18.418 1.00 48.62  ? 363 ASN A N   1 
ATOM 2334  C CA  . ASN A 1 363 ? -14.050 -23.151 -18.347 1.00 45.30  ? 363 ASN A CA  1 
ATOM 2335  C C   . ASN A 1 363 ? -14.622 -22.331 -19.494 1.00 47.97  ? 363 ASN A C   1 
ATOM 2336  O O   . ASN A 1 363 ? -15.183 -21.250 -19.283 1.00 44.55  ? 363 ASN A O   1 
ATOM 2337  C CB  . ASN A 1 363 ? -12.520 -23.103 -18.363 1.00 49.35  ? 363 ASN A CB  1 
ATOM 2338  C CG  . ASN A 1 363 ? -11.895 -23.832 -17.188 1.00 45.78  ? 363 ASN A CG  1 
ATOM 2339  O OD1 . ASN A 1 363 ? -12.549 -24.087 -16.174 1.00 48.29  ? 363 ASN A OD1 1 
ATOM 2340  N ND2 . ASN A 1 363 ? -10.615 -24.165 -17.314 1.00 40.11  ? 363 ASN A ND2 1 
ATOM 2341  N N   . GLY A 1 364 ? -14.513 -22.851 -20.719 1.00 52.09  ? 364 GLY A N   1 
ATOM 2342  C CA  . GLY A 1 364 ? -14.949 -22.139 -21.906 1.00 50.30  ? 364 GLY A CA  1 
ATOM 2343  C C   . GLY A 1 364 ? -16.375 -21.645 -21.816 1.00 51.80  ? 364 GLY A C   1 
ATOM 2344  O O   . GLY A 1 364 ? -16.611 -20.433 -21.787 1.00 50.64  ? 364 GLY A O   1 
ATOM 2345  N N   . LYS A 1 365 ? -17.332 -22.579 -21.747 1.00 47.06  ? 365 LYS A N   1 
ATOM 2346  C CA  . LYS A 1 365 ? -18.730 -22.200 -21.566 1.00 46.84  ? 365 LYS A CA  1 
ATOM 2347  C C   . LYS A 1 365 ? -18.912 -21.275 -20.369 1.00 47.18  ? 365 LYS A C   1 
ATOM 2348  O O   . LYS A 1 365 ? -19.771 -20.386 -20.409 1.00 43.12  ? 365 LYS A O   1 
ATOM 2349  C CB  . LYS A 1 365 ? -19.610 -23.443 -21.416 1.00 41.83  ? 365 LYS A CB  1 
ATOM 2350  C CG  . LYS A 1 365 ? -19.256 -24.341 -20.238 1.00 48.23  ? 365 LYS A CG  1 
ATOM 2351  C CD  . LYS A 1 365 ? -19.972 -25.686 -20.344 1.00 53.08  ? 365 LYS A CD  1 
ATOM 2352  C CE  . LYS A 1 365 ? -21.479 -25.507 -20.479 1.00 53.52  ? 365 LYS A CE  1 
ATOM 2353  N NZ  . LYS A 1 365 ? -22.186 -26.812 -20.620 1.00 57.49  ? 365 LYS A NZ  1 
ATOM 2354  N N   . LEU A 1 366 ? -18.118 -21.457 -19.310 1.00 49.42  ? 366 LEU A N   1 
ATOM 2355  C CA  . LEU A 1 366 ? -18.157 -20.523 -18.189 1.00 41.05  ? 366 LEU A CA  1 
ATOM 2356  C C   . LEU A 1 366 ? -17.974 -19.089 -18.679 1.00 48.43  ? 366 LEU A C   1 
ATOM 2357  O O   . LEU A 1 366 ? -18.847 -18.235 -18.482 1.00 46.00  ? 366 LEU A O   1 
ATOM 2358  C CB  . LEU A 1 366 ? -17.086 -20.887 -17.161 1.00 41.22  ? 366 LEU A CB  1 
ATOM 2359  C CG  . LEU A 1 366 ? -17.041 -20.007 -15.909 1.00 45.48  ? 366 LEU A CG  1 
ATOM 2360  C CD1 . LEU A 1 366 ? -18.299 -20.160 -15.066 1.00 55.44  ? 366 LEU A CD1 1 
ATOM 2361  C CD2 . LEU A 1 366 ? -15.801 -20.330 -15.090 1.00 39.41  ? 366 LEU A CD2 1 
ATOM 2362  N N   . ALA A 1 367 ? -16.857 -18.816 -19.357 1.00 52.54  ? 367 ALA A N   1 
ATOM 2363  C CA  . ALA A 1 367 ? -16.659 -17.491 -19.938 1.00 57.24  ? 367 ALA A CA  1 
ATOM 2364  C C   . ALA A 1 367 ? -17.699 -17.165 -21.000 1.00 52.27  ? 367 ALA A C   1 
ATOM 2365  O O   . ALA A 1 367 ? -17.974 -15.984 -21.242 1.00 53.56  ? 367 ALA A O   1 
ATOM 2366  C CB  . ALA A 1 367 ? -15.246 -17.370 -20.508 1.00 48.96  ? 367 ALA A CB  1 
ATOM 2367  N N   . ALA A 1 368 ? -18.306 -18.180 -21.620 1.00 48.25  ? 368 ALA A N   1 
ATOM 2368  C CA  . ALA A 1 368 ? -19.419 -17.951 -22.533 1.00 54.89  ? 368 ALA A CA  1 
ATOM 2369  C C   . ALA A 1 368 ? -20.729 -17.711 -21.802 1.00 55.22  ? 368 ALA A C   1 
ATOM 2370  O O   . ALA A 1 368 ? -21.617 -17.046 -22.345 1.00 58.13  ? 368 ALA A O   1 
ATOM 2371  C CB  . ALA A 1 368 ? -19.577 -19.130 -23.491 1.00 50.24  ? 368 ALA A CB  1 
ATOM 2372  N N   . GLU A 1 369 ? -20.859 -18.221 -20.578 1.00 50.44  ? 369 GLU A N   1 
ATOM 2373  C CA  . GLU A 1 369 ? -22.066 -17.984 -19.794 1.00 47.63  ? 369 GLU A CA  1 
ATOM 2374  C C   . GLU A 1 369 ? -22.166 -16.526 -19.364 1.00 52.11  ? 369 GLU A C   1 
ATOM 2375  O O   . GLU A 1 369 ? -23.257 -15.941 -19.386 1.00 48.30  ? 369 GLU A O   1 
ATOM 2376  C CB  . GLU A 1 369 ? -22.086 -18.913 -18.580 1.00 50.26  ? 369 GLU A CB  1 
ATOM 2377  C CG  . GLU A 1 369 ? -23.078 -18.541 -17.493 1.00 50.21  ? 369 GLU A CG  1 
ATOM 2378  C CD  . GLU A 1 369 ? -23.020 -19.494 -16.311 1.00 64.03  ? 369 GLU A CD  1 
ATOM 2379  O OE1 . GLU A 1 369 ? -22.993 -20.724 -16.540 1.00 61.54  ? 369 GLU A OE1 1 
ATOM 2380  O OE2 . GLU A 1 369 ? -22.985 -19.018 -15.155 1.00 66.18  ? 369 GLU A OE2 1 
ATOM 2381  N N   . VAL A 1 370 ? -21.041 -15.919 -18.978 1.00 49.13  ? 370 VAL A N   1 
ATOM 2382  C CA  . VAL A 1 370 ? -21.046 -14.526 -18.531 1.00 43.90  ? 370 VAL A CA  1 
ATOM 2383  C C   . VAL A 1 370 ? -21.008 -13.534 -19.682 1.00 47.28  ? 370 VAL A C   1 
ATOM 2384  O O   . VAL A 1 370 ? -21.295 -12.349 -19.472 1.00 52.46  ? 370 VAL A O   1 
ATOM 2385  C CB  . VAL A 1 370 ? -19.866 -14.250 -17.581 1.00 55.10  ? 370 VAL A CB  1 
ATOM 2386  C CG1 . VAL A 1 370 ? -19.928 -15.181 -16.377 1.00 55.11  ? 370 VAL A CG1 1 
ATOM 2387  C CG2 . VAL A 1 370 ? -18.544 -14.410 -18.314 1.00 58.17  ? 370 VAL A CG2 1 
ATOM 2388  N N   . GLY A 1 371 ? -20.657 -13.980 -20.886 1.00 51.75  ? 371 GLY A N   1 
ATOM 2389  C CA  . GLY A 1 371 ? -20.741 -13.147 -22.068 1.00 56.46  ? 371 GLY A CA  1 
ATOM 2390  C C   . GLY A 1 371 ? -19.451 -12.509 -22.537 1.00 55.62  ? 371 GLY A C   1 
ATOM 2391  O O   . GLY A 1 371 ? -19.507 -11.597 -23.370 1.00 51.68  ? 371 GLY A O   1 
ATOM 2392  N N   . VAL A 1 372 ? -18.300 -12.950 -22.044 1.00 55.84  ? 372 VAL A N   1 
ATOM 2393  C CA  . VAL A 1 372 ? -17.019 -12.372 -22.437 1.00 50.52  ? 372 VAL A CA  1 
ATOM 2394  C C   . VAL A 1 372 ? -16.279 -13.271 -23.431 1.00 53.89  ? 372 VAL A C   1 
ATOM 2395  O O   . VAL A 1 372 ? -15.078 -13.104 -23.639 1.00 53.41  ? 372 VAL A O   1 
ATOM 2396  C CB  . VAL A 1 372 ? -16.142 -12.058 -21.215 1.00 44.35  ? 372 VAL A CB  1 
ATOM 2397  C CG1 . VAL A 1 372 ? -16.841 -11.061 -20.303 1.00 46.65  ? 372 VAL A CG1 1 
ATOM 2398  C CG2 . VAL A 1 372 ? -15.793 -13.334 -20.465 1.00 43.47  ? 372 VAL A CG2 1 
ATOM 2399  N N   . GLY A 1 373 ? -16.976 -14.220 -24.048 1.00 56.10  ? 373 GLY A N   1 
ATOM 2400  C CA  . GLY A 1 373 ? -16.337 -15.091 -25.014 1.00 56.97  ? 373 GLY A CA  1 
ATOM 2401  C C   . GLY A 1 373 ? -17.370 -15.901 -25.766 1.00 47.55  ? 373 GLY A C   1 
ATOM 2402  O O   . GLY A 1 373 ? -18.572 -15.824 -25.500 1.00 54.02  ? 373 GLY A O   1 
ATOM 2403  N N   . MET A 1 374 ? -16.876 -16.686 -26.721 1.00 44.36  ? 374 MET A N   1 
ATOM 2404  C CA  . MET A 1 374 ? -17.733 -17.552 -27.519 1.00 45.78  ? 374 MET A CA  1 
ATOM 2405  C C   . MET A 1 374 ? -16.959 -18.794 -27.933 1.00 45.40  ? 374 MET A C   1 
ATOM 2406  O O   . MET A 1 374 ? -15.781 -18.710 -28.287 1.00 46.75  ? 374 MET A O   1 
ATOM 2407  C CB  . MET A 1 374 ? -18.260 -16.838 -28.766 1.00 53.22  ? 374 MET A CB  1 
ATOM 2408  C CG  . MET A 1 374 ? -19.380 -17.594 -29.464 1.00 60.78  ? 374 MET A CG  1 
ATOM 2409  S SD  . MET A 1 374 ? -19.345 -17.442 -31.260 1.00 74.59  ? 374 MET A SD  1 
ATOM 2410  C CE  . MET A 1 374 ? -19.409 -15.664 -31.454 1.00 69.10  ? 374 MET A CE  1 
ATOM 2411  N N   . GLU A 1 375 ? -17.627 -19.942 -27.887 1.00 53.49  ? 375 GLU A N   1 
ATOM 2412  C CA  . GLU A 1 375 ? -17.019 -21.209 -28.261 1.00 62.05  ? 375 GLU A CA  1 
ATOM 2413  C C   . GLU A 1 375 ? -17.245 -21.497 -29.739 1.00 59.73  ? 375 GLU A C   1 
ATOM 2414  O O   . GLU A 1 375 ? -18.259 -21.099 -30.323 1.00 54.51  ? 375 GLU A O   1 
ATOM 2415  C CB  . GLU A 1 375 ? -17.593 -22.356 -27.427 1.00 60.71  ? 375 GLU A CB  1 
ATOM 2416  C CG  . GLU A 1 375 ? -18.052 -21.957 -26.042 1.00 52.74  ? 375 GLU A CG  1 
ATOM 2417  C CD  . GLU A 1 375 ? -18.563 -23.138 -25.243 1.00 60.54  ? 375 GLU A CD  1 
ATOM 2418  O OE1 . GLU A 1 375 ? -17.842 -24.156 -25.159 1.00 58.79  ? 375 GLU A OE1 1 
ATOM 2419  O OE2 . GLU A 1 375 ? -19.689 -23.054 -24.710 1.00 65.79  ? 375 GLU A OE2 1 
ATOM 2420  N N   . VAL A 1 376 ? -16.286 -22.199 -30.345 1.00 58.53  ? 376 VAL A N   1 
ATOM 2421  C CA  . VAL A 1 376 ? -16.465 -22.650 -31.717 1.00 68.14  ? 376 VAL A CA  1 
ATOM 2422  C C   . VAL A 1 376 ? -17.440 -23.823 -31.732 1.00 75.42  ? 376 VAL A C   1 
ATOM 2423  O O   . VAL A 1 376 ? -17.490 -24.634 -30.796 1.00 77.42  ? 376 VAL A O   1 
ATOM 2424  C CB  . VAL A 1 376 ? -15.119 -23.027 -32.359 1.00 72.60  ? 376 VAL A CB  1 
ATOM 2425  C CG1 . VAL A 1 376 ? -14.122 -21.895 -32.198 1.00 65.50  ? 376 VAL A CG1 1 
ATOM 2426  C CG2 . VAL A 1 376 ? -14.569 -24.313 -31.766 1.00 74.40  ? 376 VAL A CG2 1 
ATOM 2427  N N   . VAL A 1 377 ? -18.237 -23.905 -32.792 1.00 76.76  ? 377 VAL A N   1 
ATOM 2428  C CA  . VAL A 1 377 ? -19.253 -24.943 -32.918 1.00 77.50  ? 377 VAL A CA  1 
ATOM 2429  C C   . VAL A 1 377 ? -18.615 -26.166 -33.560 1.00 78.58  ? 377 VAL A C   1 
ATOM 2430  O O   . VAL A 1 377 ? -18.137 -26.102 -34.698 1.00 95.88  ? 377 VAL A O   1 
ATOM 2431  C CB  . VAL A 1 377 ? -20.455 -24.448 -33.734 1.00 82.15  ? 377 VAL A CB  1 
ATOM 2432  C CG1 . VAL A 1 377 ? -21.605 -25.442 -33.638 1.00 69.46  ? 377 VAL A CG1 1 
ATOM 2433  C CG2 . VAL A 1 377 ? -20.890 -23.071 -33.259 1.00 67.68  ? 377 VAL A CG2 1 
ATOM 2434  N N   . ARG A 1 378 ? -18.570 -27.274 -32.812 1.00 78.69  ? 378 ARG A N   1 
ATOM 2435  C CA  . ARG A 1 378 ? -17.923 -28.516 -33.317 1.00 93.25  ? 378 ARG A CA  1 
ATOM 2436  C C   . ARG A 1 378 ? -18.793 -29.146 -34.408 1.00 100.18 ? 378 ARG A C   1 
ATOM 2437  O O   . ARG A 1 378 ? -19.980 -29.410 -34.134 1.00 106.60 ? 378 ARG A O   1 
ATOM 2438  C CB  . ARG A 1 378 ? -17.700 -29.501 -32.165 1.00 100.92 ? 378 ARG A CB  1 
ATOM 2439  C CG  . ARG A 1 378 ? -16.704 -30.608 -32.476 1.00 107.48 ? 378 ARG A CG  1 
ATOM 2440  C CD  . ARG A 1 378 ? -16.149 -31.254 -31.221 1.00 109.42 ? 378 ARG A CD  1 
ATOM 2441  N NE  . ARG A 1 378 ? -14.694 -31.229 -31.180 1.00 107.98 ? 378 ARG A NE  1 
ATOM 2442  C CZ  . ARG A 1 378 ? -13.978 -31.066 -30.073 1.00 99.20  ? 378 ARG A CZ  1 
ATOM 2443  N NH1 . ARG A 1 378 ? -14.584 -30.912 -28.909 1.00 87.22  ? 378 ARG A NH1 1 
ATOM 2444  N NH2 . ARG A 1 378 ? -12.659 -31.052 -30.135 1.00 95.77  ? 378 ARG A NH2 1 
ATOM 2445  N N   . ASP A 1 379 ? -18.217 -29.381 -35.590 1.00 102.28 ? 379 ASP A N   1 
ATOM 2446  C CA  . ASP A 1 379 ? -18.971 -30.034 -36.695 1.00 105.68 ? 379 ASP A CA  1 
ATOM 2447  C C   . ASP A 1 379 ? -18.790 -31.553 -36.589 1.00 113.35 ? 379 ASP A C   1 
ATOM 2448  O O   . ASP A 1 379 ? -19.706 -32.285 -37.012 1.00 121.78 ? 379 ASP A O   1 
ATOM 2449  C CB  . ASP A 1 379 ? -18.531 -29.500 -38.060 1.00 116.93 ? 379 ASP A CB  1 
ATOM 2450  C CG  . ASP A 1 379 ? -18.982 -28.073 -38.318 1.00 129.28 ? 379 ASP A CG  1 
ATOM 2451  O OD1 . ASP A 1 379 ? -19.866 -27.597 -37.578 1.00 129.56 ? 379 ASP A OD1 1 
ATOM 2452  O OD2 . ASP A 1 379 ? -18.442 -27.452 -39.254 1.00 130.92 ? 379 ASP A OD2 1 
ATOM 2453  N N   . GLU A 1 380 ? -17.654 -31.999 -36.042 1.00 112.18 ? 380 GLU A N   1 
ATOM 2454  C CA  . GLU A 1 380 ? -17.397 -33.454 -35.876 1.00 114.68 ? 380 GLU A CA  1 
ATOM 2455  C C   . GLU A 1 380 ? -17.467 -33.807 -34.387 1.00 121.16 ? 380 GLU A C   1 
ATOM 2456  O O   . GLU A 1 380 ? -18.414 -33.349 -33.719 1.00 126.61 ? 380 GLU A O   1 
ATOM 2457  C CB  . GLU A 1 380 ? -16.035 -33.820 -36.468 1.00 117.61 ? 380 GLU A CB  1 
ATOM 2458  C CG  . GLU A 1 380 ? -15.970 -33.673 -37.978 1.00 125.92 ? 380 GLU A CG  1 
ATOM 2459  C CD  . GLU A 1 380 ? -14.601 -33.965 -38.569 1.00 138.64 ? 380 GLU A CD  1 
ATOM 2460  O OE1 . GLU A 1 380 ? -13.640 -34.101 -37.788 1.00 133.81 ? 380 GLU A OE1 1 
ATOM 2461  O OE2 . GLU A 1 380 ? -14.504 -34.066 -39.808 1.00 137.62 ? 380 GLU A OE2 1 
ATOM 2462  N N   . ASN A 1 381 ? -16.506 -34.594 -33.894 1.00 121.84 ? 381 ASN A N   1 
ATOM 2463  C CA  . ASN A 1 381 ? -16.458 -34.961 -32.454 1.00 122.31 ? 381 ASN A CA  1 
ATOM 2464  C C   . ASN A 1 381 ? -15.007 -34.853 -31.984 1.00 122.48 ? 381 ASN A C   1 
ATOM 2465  O O   . ASN A 1 381 ? -14.790 -34.576 -30.788 1.00 115.00 ? 381 ASN A O   1 
ATOM 2466  C CB  . ASN A 1 381 ? -17.049 -36.350 -32.189 1.00 112.56 ? 381 ASN A CB  1 
ATOM 2467  C CG  . ASN A 1 381 ? -16.733 -37.360 -33.272 1.00 108.81 ? 381 ASN A CG  1 
ATOM 2468  O OD1 . ASN A 1 381 ? -15.613 -37.857 -33.358 1.00 105.32 ? 381 ASN A OD1 1 
ATOM 2469  N ND2 . ASN A 1 381 ? -17.717 -37.680 -34.097 1.00 113.41 ? 381 ASN A ND2 1 
ATOM 2470  N N   . GLY A 1 382 ? -14.055 -35.057 -32.899 1.00 120.37 ? 382 GLY A N   1 
ATOM 2471  C CA  . GLY A 1 382 ? -12.626 -34.942 -32.550 1.00 121.08 ? 382 GLY A CA  1 
ATOM 2472  C C   . GLY A 1 382 ? -12.154 -33.503 -32.644 1.00 119.24 ? 382 GLY A C   1 
ATOM 2473  O O   . GLY A 1 382 ? -11.368 -33.084 -31.771 1.00 113.64 ? 382 GLY A O   1 
ATOM 2474  N N   . LYS A 1 383 ? -12.611 -32.789 -33.669 1.00 114.21 ? 383 LYS A N   1 
ATOM 2475  C CA  . LYS A 1 383 ? -12.058 -31.429 -33.840 1.00 114.10 ? 383 LYS A CA  1 
ATOM 2476  C C   . LYS A 1 383 ? -13.049 -30.505 -34.533 1.00 104.00 ? 383 LYS A C   1 
ATOM 2477  O O   . LYS A 1 383 ? -14.198 -30.911 -34.773 1.00 105.37 ? 383 LYS A O   1 
ATOM 2478  C CB  . LYS A 1 383 ? -10.739 -31.478 -34.617 1.00 119.54 ? 383 LYS A CB  1 
ATOM 2479  C CG  . LYS A 1 383 ? -10.795 -32.158 -35.979 1.00 118.12 ? 383 LYS A CG  1 
ATOM 2480  C CD  . LYS A 1 383 ? -9.611  -31.814 -36.857 1.00 116.44 ? 383 LYS A CD  1 
ATOM 2481  C CE  . LYS A 1 383 ? -9.087  -32.993 -37.652 1.00 122.03 ? 383 LYS A CE  1 
ATOM 2482  N NZ  . LYS A 1 383 ? -8.494  -34.038 -36.783 1.00 129.70 ? 383 LYS A NZ  1 
ATOM 2483  N N   . TYR A 1 384 ? -12.575 -29.308 -34.849 1.00 99.67  ? 384 TYR A N   1 
ATOM 2484  C CA  . TYR A 1 384 ? -13.447 -28.304 -35.484 1.00 97.05  ? 384 TYR A CA  1 
ATOM 2485  C C   . TYR A 1 384 ? -12.949 -28.055 -36.903 1.00 98.71  ? 384 TYR A C   1 
ATOM 2486  O O   . TYR A 1 384 ? -11.873 -28.568 -37.263 1.00 96.61  ? 384 TYR A O   1 
ATOM 2487  C CB  . TYR A 1 384 ? -13.345 -27.019 -34.672 1.00 95.02  ? 384 TYR A CB  1 
ATOM 2488  C CG  . TYR A 1 384 ? -13.322 -27.224 -33.182 1.00 89.62  ? 384 TYR A CG  1 
ATOM 2489  C CD1 . TYR A 1 384 ? -14.458 -27.638 -32.517 1.00 98.24  ? 384 TYR A CD1 1 
ATOM 2490  C CD2 . TYR A 1 384 ? -12.180 -26.986 -32.435 1.00 75.54  ? 384 TYR A CD2 1 
ATOM 2491  C CE1 . TYR A 1 384 ? -14.468 -27.806 -31.146 1.00 93.91  ? 384 TYR A CE1 1 
ATOM 2492  C CE2 . TYR A 1 384 ? -12.169 -27.158 -31.062 1.00 79.19  ? 384 TYR A CE2 1 
ATOM 2493  C CZ  . TYR A 1 384 ? -13.320 -27.568 -30.418 1.00 82.58  ? 384 TYR A CZ  1 
ATOM 2494  O OH  . TYR A 1 384 ? -13.356 -27.743 -29.071 1.00 81.78  ? 384 TYR A OH  1 
ATOM 2495  N N   . LYS A 1 385 ? -13.707 -27.269 -37.668 1.00 101.88 ? 385 LYS A N   1 
ATOM 2496  C CA  . LYS A 1 385 ? -13.353 -27.027 -39.085 1.00 95.63  ? 385 LYS A CA  1 
ATOM 2497  C C   . LYS A 1 385 ? -13.058 -25.541 -39.276 1.00 95.38  ? 385 LYS A C   1 
ATOM 2498  O O   . LYS A 1 385 ? -13.493 -24.757 -38.426 1.00 93.99  ? 385 LYS A O   1 
ATOM 2499  C CB  . LYS A 1 385 ? -14.498 -27.529 -39.965 1.00 100.19 ? 385 LYS A CB  1 
ATOM 2500  C CG  . LYS A 1 385 ? -14.824 -29.008 -39.819 1.00 104.39 ? 385 LYS A CG  1 
ATOM 2501  C CD  . LYS A 1 385 ? -15.748 -29.513 -40.902 1.00 119.15 ? 385 LYS A CD  1 
ATOM 2502  C CE  . LYS A 1 385 ? -16.159 -30.956 -40.709 1.00 123.43 ? 385 LYS A CE  1 
ATOM 2503  N NZ  . LYS A 1 385 ? -17.498 -31.221 -41.283 1.00 120.40 ? 385 LYS A NZ  1 
ATOM 2504  N N   . ARG A 1 386 ? -12.359 -25.175 -40.351 1.00 93.79  ? 386 ARG A N   1 
ATOM 2505  C CA  . ARG A 1 386 ? -11.935 -23.770 -40.550 1.00 84.89  ? 386 ARG A CA  1 
ATOM 2506  C C   . ARG A 1 386 ? -13.127 -22.820 -40.522 1.00 86.73  ? 386 ARG A C   1 
ATOM 2507  O O   . ARG A 1 386 ? -12.996 -21.756 -39.916 1.00 88.56  ? 386 ARG A O   1 
ATOM 2508  C CB  . ARG A 1 386 ? -11.263 -23.667 -41.918 1.00 99.52  ? 386 ARG A CB  1 
ATOM 2509  C CG  . ARG A 1 386 ? -10.219 -24.745 -42.165 1.00 103.23 ? 386 ARG A CG  1 
ATOM 2510  C CD  . ARG A 1 386 ? -10.323 -25.455 -43.500 1.00 99.94  ? 386 ARG A CD  1 
ATOM 2511  N NE  . ARG A 1 386 ? -9.091  -26.189 -43.751 1.00 111.56 ? 386 ARG A NE  1 
ATOM 2512  C CZ  . ARG A 1 386 ? -9.013  -27.339 -44.408 1.00 110.68 ? 386 ARG A CZ  1 
ATOM 2513  N NH1 . ARG A 1 386 ? -10.104 -27.900 -44.897 1.00 110.34 ? 386 ARG A NH1 1 
ATOM 2514  N NH2 . ARG A 1 386 ? -7.839  -27.923 -44.576 1.00 109.98 ? 386 ARG A NH2 1 
ATOM 2515  N N   . GLU A 1 387 ? -14.218 -23.163 -41.199 1.00 92.49  ? 387 GLU A N   1 
ATOM 2516  C CA  . GLU A 1 387 ? -15.430 -22.305 -41.119 1.00 93.73  ? 387 GLU A CA  1 
ATOM 2517  C C   . GLU A 1 387 ? -15.779 -22.025 -39.654 1.00 93.15  ? 387 GLU A C   1 
ATOM 2518  O O   . GLU A 1 387 ? -15.854 -20.840 -39.301 1.00 94.27  ? 387 GLU A O   1 
ATOM 2519  C CB  . GLU A 1 387 ? -16.607 -22.962 -41.841 1.00 94.55  ? 387 GLU A CB  1 
ATOM 2520  C CG  . GLU A 1 387 ? -16.811 -22.440 -43.252 1.00 105.11 ? 387 GLU A CG  1 
ATOM 2521  C CD  . GLU A 1 387 ? -16.803 -20.927 -43.385 1.00 108.59 ? 387 GLU A CD  1 
ATOM 2522  O OE1 . GLU A 1 387 ? -17.726 -20.282 -42.851 1.00 101.46 ? 387 GLU A OE1 1 
ATOM 2523  O OE2 . GLU A 1 387 ? -15.879 -20.396 -44.033 1.00 115.06 ? 387 GLU A OE2 1 
ATOM 2524  N N   . GLY A 1 388 ? -16.000 -23.070 -38.847 1.00 94.67  ? 388 GLY A N   1 
ATOM 2525  C CA  . GLY A 1 388 ? -16.355 -22.884 -37.450 1.00 90.50  ? 388 GLY A CA  1 
ATOM 2526  C C   . GLY A 1 388 ? -15.437 -21.923 -36.720 1.00 85.13  ? 388 GLY A C   1 
ATOM 2527  O O   . GLY A 1 388 ? -15.873 -21.209 -35.812 1.00 87.03  ? 388 GLY A O   1 
ATOM 2528  N N   . ILE A 1 389 ? -14.162 -21.879 -37.107 1.00 83.99  ? 389 ILE A N   1 
ATOM 2529  C CA  . ILE A 1 389 ? -13.207 -20.991 -36.454 1.00 82.79  ? 389 ILE A CA  1 
ATOM 2530  C C   . ILE A 1 389 ? -13.306 -19.580 -37.021 1.00 86.34  ? 389 ILE A C   1 
ATOM 2531  O O   . ILE A 1 389 ? -13.379 -18.596 -36.273 1.00 87.57  ? 389 ILE A O   1 
ATOM 2532  C CB  . ILE A 1 389 ? -11.782 -21.555 -36.596 1.00 75.08  ? 389 ILE A CB  1 
ATOM 2533  C CG1 . ILE A 1 389 ? -11.674 -22.909 -35.893 1.00 76.73  ? 389 ILE A CG1 1 
ATOM 2534  C CG2 . ILE A 1 389 ? -10.758 -20.570 -36.053 1.00 80.40  ? 389 ILE A CG2 1 
ATOM 2535  C CD1 . ILE A 1 389 ? -10.293 -23.517 -35.948 1.00 74.34  ? 389 ILE A CD1 1 
ATOM 2536  N N   . ALA A 1 390 ? -13.294 -19.469 -38.350 1.00 84.97  ? 390 ALA A N   1 
ATOM 2537  C CA  . ALA A 1 390 ? -13.342 -18.159 -38.990 1.00 86.62  ? 390 ALA A CA  1 
ATOM 2538  C C   . ALA A 1 390 ? -14.634 -17.425 -38.651 1.00 80.32  ? 390 ALA A C   1 
ATOM 2539  O O   . ALA A 1 390 ? -14.621 -16.210 -38.420 1.00 81.52  ? 390 ALA A O   1 
ATOM 2540  C CB  . ALA A 1 390 ? -13.193 -18.310 -40.503 1.00 96.21  ? 390 ALA A CB  1 
ATOM 2541  N N   . GLU A 1 391 ? -15.757 -18.144 -38.621 1.00 82.38  ? 391 GLU A N   1 
ATOM 2542  C CA  . GLU A 1 391 ? -17.031 -17.514 -38.294 1.00 84.62  ? 391 GLU A CA  1 
ATOM 2543  C C   . GLU A 1 391 ? -16.977 -16.852 -36.925 1.00 82.31  ? 391 GLU A C   1 
ATOM 2544  O O   . GLU A 1 391 ? -17.311 -15.671 -36.787 1.00 77.30  ? 391 GLU A O   1 
ATOM 2545  C CB  . GLU A 1 391 ? -18.162 -18.542 -38.349 1.00 84.17  ? 391 GLU A CB  1 
ATOM 2546  C CG  . GLU A 1 391 ? -18.686 -18.820 -39.751 1.00 90.15  ? 391 GLU A CG  1 
ATOM 2547  C CD  . GLU A 1 391 ? -19.858 -19.783 -39.752 1.00 98.37  ? 391 GLU A CD  1 
ATOM 2548  O OE1 . GLU A 1 391 ? -20.415 -20.041 -38.666 1.00 104.67 ? 391 GLU A OE1 1 
ATOM 2549  O OE2 . GLU A 1 391 ? -20.217 -20.282 -40.839 1.00 86.75  ? 391 GLU A OE2 1 
ATOM 2550  N N   . VAL A 1 392 ? -16.538 -17.592 -35.904 1.00 77.61  ? 392 VAL A N   1 
ATOM 2551  C CA  . VAL A 1 392 ? -16.545 -17.036 -34.557 1.00 80.03  ? 392 VAL A CA  1 
ATOM 2552  C C   . VAL A 1 392 ? -15.503 -15.932 -34.419 1.00 80.82  ? 392 VAL A C   1 
ATOM 2553  O O   . VAL A 1 392 ? -15.739 -14.941 -33.716 1.00 79.02  ? 392 VAL A O   1 
ATOM 2554  C CB  . VAL A 1 392 ? -16.356 -18.145 -33.505 1.00 85.15  ? 392 VAL A CB  1 
ATOM 2555  C CG1 . VAL A 1 392 ? -17.411 -19.229 -33.688 1.00 80.10  ? 392 VAL A CG1 1 
ATOM 2556  C CG2 . VAL A 1 392 ? -14.967 -18.743 -33.590 1.00 84.82  ? 392 VAL A CG2 1 
ATOM 2557  N N   . ILE A 1 393 ? -14.358 -16.056 -35.100 1.00 79.37  ? 393 ILE A N   1 
ATOM 2558  C CA  . ILE A 1 393 ? -13.359 -14.987 -35.042 1.00 74.92  ? 393 ILE A CA  1 
ATOM 2559  C C   . ILE A 1 393 ? -13.935 -13.697 -35.611 1.00 73.15  ? 393 ILE A C   1 
ATOM 2560  O O   . ILE A 1 393 ? -13.848 -12.627 -34.991 1.00 73.13  ? 393 ILE A O   1 
ATOM 2561  C CB  . ILE A 1 393 ? -12.071 -15.403 -35.773 1.00 71.61  ? 393 ILE A CB  1 
ATOM 2562  C CG1 . ILE A 1 393 ? -11.356 -16.507 -34.997 1.00 69.48  ? 393 ILE A CG1 1 
ATOM 2563  C CG2 . ILE A 1 393 ? -11.152 -14.201 -35.954 1.00 70.00  ? 393 ILE A CG2 1 
ATOM 2564  C CD1 . ILE A 1 393 ? -10.088 -16.989 -35.662 1.00 71.62  ? 393 ILE A CD1 1 
ATOM 2565  N N   . ARG A 1 394 ? -14.552 -13.779 -36.794 1.00 75.50  ? 394 ARG A N   1 
ATOM 2566  C CA  . ARG A 1 394 ? -15.141 -12.590 -37.403 1.00 81.08  ? 394 ARG A CA  1 
ATOM 2567  C C   . ARG A 1 394 ? -16.271 -12.036 -36.546 1.00 77.77  ? 394 ARG A C   1 
ATOM 2568  O O   . ARG A 1 394 ? -16.383 -10.817 -36.373 1.00 75.43  ? 394 ARG A O   1 
ATOM 2569  C CB  . ARG A 1 394 ? -15.645 -12.908 -38.812 1.00 80.08  ? 394 ARG A CB  1 
ATOM 2570  C CG  . ARG A 1 394 ? -14.574 -13.406 -39.766 1.00 82.95  ? 394 ARG A CG  1 
ATOM 2571  C CD  . ARG A 1 394 ? -15.158 -13.719 -41.137 1.00 90.13  ? 394 ARG A CD  1 
ATOM 2572  N NE  . ARG A 1 394 ? -15.227 -12.539 -41.990 1.00 96.89  ? 394 ARG A NE  1 
ATOM 2573  C CZ  . ARG A 1 394 ? -14.309 -12.215 -42.893 1.00 101.37 ? 394 ARG A CZ  1 
ATOM 2574  N NH1 . ARG A 1 394 ? -13.241 -12.968 -43.092 1.00 98.98  ? 394 ARG A NH1 1 
ATOM 2575  N NH2 . ARG A 1 394 ? -14.471 -11.109 -43.613 1.00 100.45 ? 394 ARG A NH2 1 
ATOM 2576  N N   . LYS A 1 395 ? -17.113 -12.916 -35.997 1.00 74.80  ? 395 LYS A N   1 
ATOM 2577  C CA  . LYS A 1 395 ? -18.231 -12.465 -35.173 1.00 73.01  ? 395 LYS A CA  1 
ATOM 2578  C C   . LYS A 1 395 ? -17.737 -11.697 -33.955 1.00 77.97  ? 395 LYS A C   1 
ATOM 2579  O O   . LYS A 1 395 ? -18.252 -10.618 -33.639 1.00 78.86  ? 395 LYS A O   1 
ATOM 2580  C CB  . LYS A 1 395 ? -19.083 -13.662 -34.744 1.00 71.77  ? 395 LYS A CB  1 
ATOM 2581  C CG  . LYS A 1 395 ? -19.888 -14.301 -35.868 1.00 78.21  ? 395 LYS A CG  1 
ATOM 2582  C CD  . LYS A 1 395 ? -20.293 -15.728 -35.516 1.00 78.19  ? 395 LYS A CD  1 
ATOM 2583  C CE  . LYS A 1 395 ? -21.571 -15.769 -34.696 1.00 75.88  ? 395 LYS A CE  1 
ATOM 2584  N NZ  . LYS A 1 395 ? -22.763 -15.424 -35.523 1.00 59.75  ? 395 LYS A NZ  1 
ATOM 2585  N N   . VAL A 1 396 ? -16.726 -12.226 -33.269 1.00 76.01  ? 396 VAL A N   1 
ATOM 2586  C CA  . VAL A 1 396 ? -16.275 -11.617 -32.022 1.00 68.52  ? 396 VAL A CA  1 
ATOM 2587  C C   . VAL A 1 396 ? -15.476 -10.348 -32.294 1.00 68.02  ? 396 VAL A C   1 
ATOM 2588  O O   . VAL A 1 396 ? -15.813 -9.266  -31.798 1.00 71.95  ? 396 VAL A O   1 
ATOM 2589  C CB  . VAL A 1 396 ? -15.457 -12.626 -31.192 1.00 67.05  ? 396 VAL A CB  1 
ATOM 2590  C CG1 . VAL A 1 396 ? -14.784 -11.926 -30.021 1.00 65.03  ? 396 VAL A CG1 1 
ATOM 2591  C CG2 . VAL A 1 396 ? -16.354 -13.748 -30.703 1.00 65.92  ? 396 VAL A CG2 1 
ATOM 2592  N N   . VAL A 1 397 ? -14.411 -10.453 -33.088 1.00 68.57  ? 397 VAL A N   1 
ATOM 2593  C CA  . VAL A 1 397 ? -13.416 -9.382  -33.094 1.00 66.29  ? 397 VAL A CA  1 
ATOM 2594  C C   . VAL A 1 397 ? -13.816 -8.235  -34.018 1.00 70.61  ? 397 VAL A C   1 
ATOM 2595  O O   . VAL A 1 397 ? -13.581 -7.065  -33.701 1.00 66.53  ? 397 VAL A O   1 
ATOM 2596  C CB  . VAL A 1 397 ? -12.030 -9.945  -33.459 1.00 69.27  ? 397 VAL A CB  1 
ATOM 2597  C CG1 . VAL A 1 397 ? -10.963 -8.869  -33.294 1.00 58.51  ? 397 VAL A CG1 1 
ATOM 2598  C CG2 . VAL A 1 397 ? -11.706 -11.155 -32.589 1.00 62.38  ? 397 VAL A CG2 1 
ATOM 2599  N N   . VAL A 1 398 ? -14.426 -8.532  -35.165 1.00 73.20  ? 398 VAL A N   1 
ATOM 2600  C CA  . VAL A 1 398 ? -14.591 -7.537  -36.223 1.00 79.06  ? 398 VAL A CA  1 
ATOM 2601  C C   . VAL A 1 398 ? -16.046 -7.270  -36.591 1.00 77.08  ? 398 VAL A C   1 
ATOM 2602  O O   . VAL A 1 398 ? -16.311 -6.300  -37.318 1.00 74.23  ? 398 VAL A O   1 
ATOM 2603  C CB  . VAL A 1 398 ? -13.793 -7.937  -37.484 1.00 80.23  ? 398 VAL A CB  1 
ATOM 2604  C CG1 . VAL A 1 398 ? -14.580 -8.917  -38.337 1.00 78.57  ? 398 VAL A CG1 1 
ATOM 2605  C CG2 . VAL A 1 398 ? -13.382 -6.710  -38.284 1.00 72.76  ? 398 VAL A CG2 1 
ATOM 2606  N N   . GLU A 1 399 ? -16.998 -8.075  -36.129 1.00 76.42  ? 399 GLU A N   1 
ATOM 2607  C CA  . GLU A 1 399 ? -18.389 -7.915  -36.526 1.00 75.18  ? 399 GLU A CA  1 
ATOM 2608  C C   . GLU A 1 399 ? -19.196 -7.243  -35.422 1.00 77.70  ? 399 GLU A C   1 
ATOM 2609  O O   . GLU A 1 399 ? -18.814 -7.240  -34.250 1.00 77.74  ? 399 GLU A O   1 
ATOM 2610  C CB  . GLU A 1 399 ? -19.010 -9.271  -36.881 1.00 75.11  ? 399 GLU A CB  1 
ATOM 2611  C CG  . GLU A 1 399 ? -19.866 -9.260  -38.146 1.00 76.80  ? 399 GLU A CG  1 
ATOM 2612  C CD  . GLU A 1 399 ? -21.253 -8.688  -37.916 1.00 85.39  ? 399 GLU A CD  1 
ATOM 2613  O OE1 . GLU A 1 399 ? -21.720 -8.715  -36.759 1.00 88.48  ? 399 GLU A OE1 1 
ATOM 2614  O OE2 . GLU A 1 399 ? -21.874 -8.210  -38.892 1.00 87.42  ? 399 GLU A OE2 1 
ATOM 2615  N N   . LYS A 1 400 ? -20.335 -6.669  -35.820 1.00 76.39  ? 400 LYS A N   1 
ATOM 2616  C CA  . LYS A 1 400 ? -21.209 -6.008  -34.856 1.00 73.15  ? 400 LYS A CA  1 
ATOM 2617  C C   . LYS A 1 400 ? -21.888 -7.004  -33.924 1.00 68.85  ? 400 LYS A C   1 
ATOM 2618  O O   . LYS A 1 400 ? -22.173 -6.670  -32.770 1.00 68.85  ? 400 LYS A O   1 
ATOM 2619  C CB  . LYS A 1 400 ? -22.269 -5.176  -35.579 1.00 71.07  ? 400 LYS A CB  1 
ATOM 2620  C CG  . LYS A 1 400 ? -21.720 -4.008  -36.373 1.00 70.08  ? 400 LYS A CG  1 
ATOM 2621  C CD  . LYS A 1 400 ? -22.845 -3.201  -37.012 1.00 72.68  ? 400 LYS A CD  1 
ATOM 2622  C CE  . LYS A 1 400 ? -22.310 -1.980  -37.743 1.00 84.80  ? 400 LYS A CE  1 
ATOM 2623  N NZ  . LYS A 1 400 ? -23.405 -1.200  -38.387 1.00 86.21  ? 400 LYS A NZ  1 
ATOM 2624  N N   . SER A 1 401 ? -22.163 -8.221  -34.405 1.00 74.72  ? 401 SER A N   1 
ATOM 2625  C CA  . SER A 1 401 ? -22.846 -9.216  -33.582 1.00 83.31  ? 401 SER A CA  1 
ATOM 2626  C C   . SER A 1 401 ? -22.060 -9.568  -32.327 1.00 76.39  ? 401 SER A C   1 
ATOM 2627  O O   . SER A 1 401 ? -22.655 -10.013 -31.338 1.00 69.29  ? 401 SER A O   1 
ATOM 2628  C CB  . SER A 1 401 ? -23.112 -10.481 -34.399 1.00 79.06  ? 401 SER A CB  1 
ATOM 2629  O OG  . SER A 1 401 ? -21.899 -11.090 -34.803 1.00 78.69  ? 401 SER A OG  1 
ATOM 2630  N N   . GLY A 1 402 ? -20.745 -9.376  -32.339 1.00 70.57  ? 402 GLY A N   1 
ATOM 2631  C CA  . GLY A 1 402 ? -19.911 -9.610  -31.182 1.00 70.11  ? 402 GLY A CA  1 
ATOM 2632  C C   . GLY A 1 402 ? -19.708 -8.408  -30.290 1.00 73.82  ? 402 GLY A C   1 
ATOM 2633  O O   . GLY A 1 402 ? -18.936 -8.494  -29.328 1.00 75.40  ? 402 GLY A O   1 
ATOM 2634  N N   . GLU A 1 403 ? -20.376 -7.283  -30.577 1.00 72.34  ? 403 GLU A N   1 
ATOM 2635  C CA  . GLU A 1 403 ? -20.242 -6.107  -29.722 1.00 69.38  ? 403 GLU A CA  1 
ATOM 2636  C C   . GLU A 1 403 ? -20.668 -6.421  -28.292 1.00 68.22  ? 403 GLU A C   1 
ATOM 2637  O O   . GLU A 1 403 ? -20.008 -6.001  -27.333 1.00 69.51  ? 403 GLU A O   1 
ATOM 2638  C CB  . GLU A 1 403 ? -21.054 -4.948  -30.294 1.00 73.60  ? 403 GLU A CB  1 
ATOM 2639  C CG  . GLU A 1 403 ? -20.473 -3.577  -29.980 1.00 77.36  ? 403 GLU A CG  1 
ATOM 2640  C CD  . GLU A 1 403 ? -21.266 -2.826  -28.929 1.00 87.42  ? 403 GLU A CD  1 
ATOM 2641  O OE1 . GLU A 1 403 ? -22.491 -3.056  -28.830 1.00 86.08  ? 403 GLU A OE1 1 
ATOM 2642  O OE2 . GLU A 1 403 ? -20.666 -2.006  -28.201 1.00 86.05  ? 403 GLU A OE2 1 
ATOM 2643  N N   . VAL A 1 404 ? -21.732 -7.196  -28.145 1.00 66.95  ? 404 VAL A N   1 
ATOM 2644  C CA  . VAL A 1 404 ? -22.118 -7.597  -26.766 1.00 70.30  ? 404 VAL A CA  1 
ATOM 2645  C C   . VAL A 1 404 ? -20.871 -8.158  -26.082 1.00 72.46  ? 404 VAL A C   1 
ATOM 2646  O O   . VAL A 1 404 ? -20.478 -7.604  -25.028 1.00 72.21  ? 404 VAL A O   1 
ATOM 2647  C CB  . VAL A 1 404 ? -23.277 -8.609  -26.775 1.00 66.68  ? 404 VAL A CB  1 
ATOM 2648  C CG1 . VAL A 1 404 ? -23.628 -9.074  -25.371 1.00 64.26  ? 404 VAL A CG1 1 
ATOM 2649  C CG2 . VAL A 1 404 ? -24.503 -8.041  -27.473 1.00 72.48  ? 404 VAL A CG2 1 
ATOM 2650  N N   . ILE A 1 405 ? -20.194 -9.117  -26.714 1.00 61.13  ? 405 ILE A N   1 
ATOM 2651  C CA  . ILE A 1 405 ? -19.052 -9.797  -26.041 1.00 61.64  ? 405 ILE A CA  1 
ATOM 2652  C C   . ILE A 1 405 ? -17.951 -8.788  -25.694 1.00 56.46  ? 405 ILE A C   1 
ATOM 2653  O O   . ILE A 1 405 ? -17.462 -8.793  -24.537 1.00 51.39  ? 405 ILE A O   1 
ATOM 2654  C CB  . ILE A 1 405 ? -18.568 -10.926 -26.967 1.00 59.93  ? 405 ILE A CB  1 
ATOM 2655  C CG1 . ILE A 1 405 ? -19.690 -11.924 -27.255 1.00 62.41  ? 405 ILE A CG1 1 
ATOM 2656  C CG2 . ILE A 1 405 ? -17.329 -11.612 -26.424 1.00 55.61  ? 405 ILE A CG2 1 
ATOM 2657  C CD1 . ILE A 1 405 ? -19.345 -12.946 -28.305 1.00 61.78  ? 405 ILE A CD1 1 
ATOM 2658  N N   . ARG A 1 406 ? -17.620 -7.911  -26.632 1.00 59.68  ? 406 ARG A N   1 
ATOM 2659  C CA  . ARG A 1 406 ? -16.504 -6.963  -26.409 1.00 55.50  ? 406 ARG A CA  1 
ATOM 2660  C C   . ARG A 1 406 ? -16.847 -5.993  -25.286 1.00 49.54  ? 406 ARG A C   1 
ATOM 2661  O O   . ARG A 1 406 ? -15.971 -5.731  -24.389 1.00 60.48  ? 406 ARG A O   1 
ATOM 2662  C CB  . ARG A 1 406 ? -16.218 -6.248  -27.729 1.00 65.21  ? 406 ARG A CB  1 
ATOM 2663  C CG  . ARG A 1 406 ? -15.816 -7.177  -28.865 1.00 64.23  ? 406 ARG A CG  1 
ATOM 2664  C CD  . ARG A 1 406 ? -15.288 -6.415  -30.065 1.00 64.26  ? 406 ARG A CD  1 
ATOM 2665  N NE  . ARG A 1 406 ? -16.284 -5.524  -30.637 1.00 72.47  ? 406 ARG A NE  1 
ATOM 2666  C CZ  . ARG A 1 406 ? -16.954 -5.760  -31.757 1.00 67.36  ? 406 ARG A CZ  1 
ATOM 2667  N NH1 . ARG A 1 406 ? -16.721 -6.859  -32.447 1.00 60.81  ? 406 ARG A NH1 1 
ATOM 2668  N NH2 . ARG A 1 406 ? -17.844 -4.888  -32.191 1.00 67.51  ? 406 ARG A NH2 1 
ATOM 2669  N N   . ARG A 1 407 ? -18.066 -5.447  -25.312 1.00 47.73  ? 407 ARG A N   1 
ATOM 2670  C CA  . ARG A 1 407 ? -18.500 -4.476  -24.272 1.00 53.72  ? 407 ARG A CA  1 
ATOM 2671  C C   . ARG A 1 407 ? -18.362 -5.124  -22.892 1.00 55.11  ? 407 ARG A C   1 
ATOM 2672  O O   . ARG A 1 407 ? -17.798 -4.475  -21.991 1.00 53.83  ? 407 ARG A O   1 
ATOM 2673  C CB  . ARG A 1 407 ? -19.943 -4.041  -24.535 1.00 60.58  ? 407 ARG A CB  1 
ATOM 2674  C CG  . ARG A 1 407 ? -20.528 -3.124  -23.471 1.00 66.25  ? 407 ARG A CG  1 
ATOM 2675  C CD  . ARG A 1 407 ? -21.981 -2.762  -23.719 1.00 71.95  ? 407 ARG A CD  1 
ATOM 2676  N NE  . ARG A 1 407 ? -22.891 -3.897  -23.653 1.00 77.86  ? 407 ARG A NE  1 
ATOM 2677  C CZ  . ARG A 1 407 ? -23.409 -4.519  -24.707 1.00 79.76  ? 407 ARG A CZ  1 
ATOM 2678  N NH1 . ARG A 1 407 ? -23.113 -4.114  -25.931 1.00 81.67  ? 407 ARG A NH1 1 
ATOM 2679  N NH2 . ARG A 1 407 ? -24.227 -5.542  -24.534 1.00 72.95  ? 407 ARG A NH2 1 
ATOM 2680  N N   . LYS A 1 408 ? -18.827 -6.365  -22.766 1.00 49.60  ? 408 LYS A N   1 
ATOM 2681  C CA  . LYS A 1 408 ? -18.808 -7.060  -21.458 1.00 49.45  ? 408 LYS A CA  1 
ATOM 2682  C C   . LYS A 1 408 ? -17.371 -7.265  -20.992 1.00 54.42  ? 408 LYS A C   1 
ATOM 2683  O O   . LYS A 1 408 ? -17.118 -7.081  -19.799 1.00 62.52  ? 408 LYS A O   1 
ATOM 2684  C CB  . LYS A 1 408 ? -19.515 -8.408  -21.578 1.00 60.77  ? 408 LYS A CB  1 
ATOM 2685  C CG  . LYS A 1 408 ? -20.983 -8.356  -21.979 1.00 72.68  ? 408 LYS A CG  1 
ATOM 2686  C CD  . LYS A 1 408 ? -21.884 -7.659  -20.979 1.00 71.65  ? 408 LYS A CD  1 
ATOM 2687  C CE  . LYS A 1 408 ? -23.343 -7.687  -21.385 1.00 71.03  ? 408 LYS A CE  1 
ATOM 2688  N NZ  . LYS A 1 408 ? -24.216 -7.032  -20.382 1.00 63.01  ? 408 LYS A NZ  1 
ATOM 2689  N N   . ALA A 1 409 ? -16.479 -7.642  -21.898 1.00 46.84  ? 409 ALA A N   1 
ATOM 2690  C CA  . ALA A 1 409 ? -15.066 -7.914  -21.542 1.00 45.77  ? 409 ALA A CA  1 
ATOM 2691  C C   . ALA A 1 409 ? -14.438 -6.657  -20.929 1.00 50.60  ? 409 ALA A C   1 
ATOM 2692  O O   . ALA A 1 409 ? -13.737 -6.790  -19.908 1.00 47.92  ? 409 ALA A O   1 
ATOM 2693  C CB  . ALA A 1 409 ? -14.306 -8.380  -22.758 1.00 43.26  ? 409 ALA A CB  1 
ATOM 2694  N N   . ARG A 1 410 ? -14.690 -5.488  -21.528 1.00 52.77  ? 410 ARG A N   1 
ATOM 2695  C CA  . ARG A 1 410 ? -14.112 -4.218  -21.035 1.00 57.33  ? 410 ARG A CA  1 
ATOM 2696  C C   . ARG A 1 410 ? -14.748 -3.842  -19.707 1.00 54.99  ? 410 ARG A C   1 
ATOM 2697  O O   . ARG A 1 410 ? -14.017 -3.438  -18.822 1.00 60.12  ? 410 ARG A O   1 
ATOM 2698  C CB  . ARG A 1 410 ? -14.441 -3.088  -22.012 1.00 58.86  ? 410 ARG A CB  1 
ATOM 2699  C CG  . ARG A 1 410 ? -13.830 -1.741  -21.653 1.00 66.96  ? 410 ARG A CG  1 
ATOM 2700  C CD  . ARG A 1 410 ? -14.847 -0.616  -21.637 1.00 73.59  ? 410 ARG A CD  1 
ATOM 2701  N NE  . ARG A 1 410 ? -14.221 0.687   -21.801 1.00 87.78  ? 410 ARG A NE  1 
ATOM 2702  C CZ  . ARG A 1 410 ? -14.864 1.849   -21.754 1.00 83.83  ? 410 ARG A CZ  1 
ATOM 2703  N NH1 . ARG A 1 410 ? -16.166 1.878   -21.529 1.00 81.09  ? 410 ARG A NH1 1 
ATOM 2704  N NH2 . ARG A 1 410 ? -14.200 2.977   -21.925 1.00 81.66  ? 410 ARG A NH2 1 
ATOM 2705  N N   . GLU A 1 411 ? -16.066 -3.967  -19.593 1.00 51.78  ? 411 GLU A N   1 
ATOM 2706  C CA  . GLU A 1 411 ? -16.762 -3.547  -18.356 1.00 60.62  ? 411 GLU A CA  1 
ATOM 2707  C C   . GLU A 1 411 ? -16.287 -4.436  -17.206 1.00 61.10  ? 411 GLU A C   1 
ATOM 2708  O O   . GLU A 1 411 ? -15.964 -3.914  -16.122 1.00 50.55  ? 411 GLU A O   1 
ATOM 2709  C CB  . GLU A 1 411 ? -18.271 -3.574  -18.589 1.00 51.98  ? 411 GLU A CB  1 
ATOM 2710  C CG  . GLU A 1 411 ? -18.779 -2.356  -19.335 1.00 60.91  ? 411 GLU A CG  1 
ATOM 2711  C CD  . GLU A 1 411 ? -20.255 -2.404  -19.688 1.00 72.57  ? 411 GLU A CD  1 
ATOM 2712  O OE1 . GLU A 1 411 ? -20.842 -3.495  -19.602 1.00 71.35  ? 411 GLU A OE1 1 
ATOM 2713  O OE2 . GLU A 1 411 ? -20.812 -1.348  -20.046 1.00 70.95  ? 411 GLU A OE2 1 
ATOM 2714  N N   . LEU A 1 412 ? -16.172 -5.730  -17.474 1.00 57.45  ? 412 LEU A N   1 
ATOM 2715  C CA  . LEU A 1 412 ? -15.713 -6.664  -16.422 1.00 62.18  ? 412 LEU A CA  1 
ATOM 2716  C C   . LEU A 1 412 ? -14.262 -6.354  -16.047 1.00 61.57  ? 412 LEU A C   1 
ATOM 2717  O O   . LEU A 1 412 ? -13.944 -6.488  -14.872 1.00 65.04  ? 412 LEU A O   1 
ATOM 2718  C CB  . LEU A 1 412 ? -15.947 -8.105  -16.877 1.00 64.97  ? 412 LEU A CB  1 
ATOM 2719  C CG  . LEU A 1 412 ? -17.409 -8.544  -16.863 1.00 63.85  ? 412 LEU A CG  1 
ATOM 2720  C CD1 . LEU A 1 412 ? -17.518 -10.056 -16.835 1.00 61.69  ? 412 LEU A CD1 1 
ATOM 2721  C CD2 . LEU A 1 412 ? -18.141 -7.953  -15.669 1.00 50.60  ? 412 LEU A CD2 1 
ATOM 2722  N N   . SER A 1 413 ? -13.421 -5.982  -17.014 1.00 61.46  ? 413 SER A N   1 
ATOM 2723  C CA  . SER A 1 413 ? -12.000 -5.627  -16.757 1.00 61.29  ? 413 SER A CA  1 
ATOM 2724  C C   . SER A 1 413 ? -11.944 -4.387  -15.881 1.00 58.02  ? 413 SER A C   1 
ATOM 2725  O O   . SER A 1 413 ? -11.151 -4.355  -14.930 1.00 56.84  ? 413 SER A O   1 
ATOM 2726  C CB  . SER A 1 413 ? -11.271 -5.386  -18.042 1.00 51.74  ? 413 SER A CB  1 
ATOM 2727  O OG  . SER A 1 413 ? -9.961  -4.902  -17.795 1.00 62.03  ? 413 SER A OG  1 
ATOM 2728  N N   . GLU A 1 414 ? -12.811 -3.428  -16.178 1.00 61.69  ? 414 GLU A N   1 
ATOM 2729  C CA  . GLU A 1 414 ? -12.856 -2.193  -15.377 1.00 63.90  ? 414 GLU A CA  1 
ATOM 2730  C C   . GLU A 1 414 ? -13.238 -2.589  -13.960 1.00 60.59  ? 414 GLU A C   1 
ATOM 2731  O O   . GLU A 1 414 ? -12.621 -2.073  -13.046 1.00 61.90  ? 414 GLU A O   1 
ATOM 2732  C CB  . GLU A 1 414 ? -13.872 -1.222  -15.973 1.00 63.81  ? 414 GLU A CB  1 
ATOM 2733  C CG  . GLU A 1 414 ? -13.388 -0.545  -17.238 1.00 64.61  ? 414 GLU A CG  1 
ATOM 2734  C CD  . GLU A 1 414 ? -14.416 0.354   -17.896 1.00 82.40  ? 414 GLU A CD  1 
ATOM 2735  O OE1 . GLU A 1 414 ? -15.620 0.073   -17.758 1.00 76.23  ? 414 GLU A OE1 1 
ATOM 2736  O OE2 . GLU A 1 414 ? -14.008 1.342   -18.534 1.00 89.77  ? 414 GLU A OE2 1 
ATOM 2737  N N   . LYS A 1 415 ? -14.201 -3.496  -13.812 1.00 57.57  ? 415 LYS A N   1 
ATOM 2738  C CA  . LYS A 1 415 ? -14.651 -3.896  -12.458 1.00 57.98  ? 415 LYS A CA  1 
ATOM 2739  C C   . LYS A 1 415 ? -13.507 -4.588  -11.730 1.00 60.12  ? 415 LYS A C   1 
ATOM 2740  O O   . LYS A 1 415 ? -13.291 -4.288  -10.556 1.00 67.58  ? 415 LYS A O   1 
ATOM 2741  C CB  . LYS A 1 415 ? -15.837 -4.852  -12.535 1.00 56.98  ? 415 LYS A CB  1 
ATOM 2742  C CG  . LYS A 1 415 ? -17.203 -4.196  -12.663 1.00 63.21  ? 415 LYS A CG  1 
ATOM 2743  C CD  . LYS A 1 415 ? -18.274 -5.148  -13.144 1.00 64.89  ? 415 LYS A CD  1 
ATOM 2744  C CE  . LYS A 1 415 ? -19.650 -4.524  -13.141 1.00 67.39  ? 415 LYS A CE  1 
ATOM 2745  N NZ  . LYS A 1 415 ? -19.633 -3.167  -13.737 1.00 75.61  ? 415 LYS A NZ  1 
ATOM 2746  N N   . MET A 1 416 ? -12.788 -5.456  -12.421 1.00 55.55  ? 416 MET A N   1 
ATOM 2747  C CA  . MET A 1 416 ? -11.732 -6.242  -11.750 1.00 59.82  ? 416 MET A CA  1 
ATOM 2748  C C   . MET A 1 416 ? -10.683 -5.259  -11.259 1.00 58.60  ? 416 MET A C   1 
ATOM 2749  O O   . MET A 1 416 ? -10.055 -5.530  -10.231 1.00 66.23  ? 416 MET A O   1 
ATOM 2750  C CB  . MET A 1 416 ? -11.143 -7.259  -12.728 1.00 58.85  ? 416 MET A CB  1 
ATOM 2751  C CG  . MET A 1 416 ? -12.090 -8.395  -13.044 1.00 52.00  ? 416 MET A CG  1 
ATOM 2752  S SD  . MET A 1 416 ? -11.508 -9.408  -14.415 1.00 66.53  ? 416 MET A SD  1 
ATOM 2753  C CE  . MET A 1 416 ? -9.960  -10.000 -13.740 1.00 45.15  ? 416 MET A CE  1 
ATOM 2754  N N   . LYS A 1 417 ? -10.519 -4.156  -11.970 1.00 58.26  ? 417 LYS A N   1 
ATOM 2755  C CA  . LYS A 1 417 ? -9.618  -3.111  -11.514 1.00 66.27  ? 417 LYS A CA  1 
ATOM 2756  C C   . LYS A 1 417 ? -10.319 -2.017  -10.723 1.00 68.99  ? 417 LYS A C   1 
ATOM 2757  O O   . LYS A 1 417 ? -9.642  -1.241  -10.038 1.00 63.78  ? 417 LYS A O   1 
ATOM 2758  C CB  . LYS A 1 417 ? -8.883  -2.484  -12.704 1.00 63.14  ? 417 LYS A CB  1 
ATOM 2759  C CG  . LYS A 1 417 ? -7.998  -3.459  -13.466 1.00 69.85  ? 417 LYS A CG  1 
ATOM 2760  C CD  . LYS A 1 417 ? -6.931  -4.067  -12.559 1.00 71.57  ? 417 LYS A CD  1 
ATOM 2761  C CE  . LYS A 1 417 ? -5.983  -3.004  -12.018 1.00 64.73  ? 417 LYS A CE  1 
ATOM 2762  N NZ  . LYS A 1 417 ? -4.923  -3.588  -11.150 1.00 72.20  ? 417 LYS A NZ  1 
ATOM 2763  N N   . GLU A 1 418 ? -11.649 -1.942  -10.791 1.00 66.26  ? 418 GLU A N   1 
ATOM 2764  C CA  . GLU A 1 418 ? -12.371 -0.937  -10.019 1.00 65.05  ? 418 GLU A CA  1 
ATOM 2765  C C   . GLU A 1 418 ? -12.431 -1.318  -8.544  1.00 66.32  ? 418 GLU A C   1 
ATOM 2766  O O   . GLU A 1 418 ? -12.165 -0.488  -7.668  1.00 75.53  ? 418 GLU A O   1 
ATOM 2767  C CB  . GLU A 1 418 ? -13.774 -0.739  -10.594 1.00 67.71  ? 418 GLU A CB  1 
ATOM 2768  C CG  . GLU A 1 418 ? -14.417 0.582   -10.214 1.00 65.96  ? 418 GLU A CG  1 
ATOM 2769  C CD  . GLU A 1 418 ? -15.551 0.966   -11.146 1.00 56.69  ? 418 GLU A CD  1 
ATOM 2770  O OE1 . GLU A 1 418 ? -15.950 0.126   -11.980 1.00 64.31  ? 418 GLU A OE1 1 
ATOM 2771  O OE2 . GLU A 1 418 ? -16.040 2.112   -11.045 1.00 54.59  ? 418 GLU A OE2 1 
ATOM 2772  N N   . LYS A 1 419 ? -12.567 -2.620  -8.274  1.00 61.87  ? 419 LYS A N   1 
ATOM 2773  C CA  . LYS A 1 419 ? -12.527 -3.120  -6.871  1.00 65.55  ? 419 LYS A CA  1 
ATOM 2774  C C   . LYS A 1 419 ? -11.117 -3.631  -6.580  1.00 65.24  ? 419 LYS A C   1 
ATOM 2775  O O   . LYS A 1 419 ? -10.988 -4.662  -5.902  1.00 60.84  ? 419 LYS A O   1 
ATOM 2776  C CB  . LYS A 1 419 ? -13.553 -4.240  -6.685  1.00 69.68  ? 419 LYS A CB  1 
ATOM 2777  C CG  . LYS A 1 419 ? -13.408 -5.437  -7.618  1.00 61.91  ? 419 LYS A CG  1 
ATOM 2778  C CD  . LYS A 1 419 ? -14.304 -6.595  -7.245  1.00 63.21  ? 419 LYS A CD  1 
ATOM 2779  C CE  . LYS A 1 419 ? -13.766 -7.928  -7.713  1.00 69.59  ? 419 LYS A CE  1 
ATOM 2780  N NZ  . LYS A 1 419 ? -13.484 -7.927  -9.166  1.00 64.74  ? 419 LYS A NZ  1 
ATOM 2781  N N   . GLY A 1 420 ? -10.097 -2.898  -7.014  1.00 66.29  ? 420 GLY A N   1 
ATOM 2782  C CA  . GLY A 1 420 ? -8.712  -3.397  -6.916  1.00 65.13  ? 420 GLY A CA  1 
ATOM 2783  C C   . GLY A 1 420 ? -8.087  -3.456  -5.545  1.00 63.57  ? 420 GLY A C   1 
ATOM 2784  O O   . GLY A 1 420 ? -8.340  -2.527  -4.769  1.00 70.53  ? 420 GLY A O   1 
ATOM 2785  N N   . GLU A 1 421 ? -7.371  -4.541  -5.238  1.00 58.50  ? 421 GLU A N   1 
ATOM 2786  C CA  . GLU A 1 421 ? -6.574  -4.681  -3.986  1.00 58.96  ? 421 GLU A CA  1 
ATOM 2787  C C   . GLU A 1 421 ? -7.431  -5.068  -2.784  1.00 51.26  ? 421 GLU A C   1 
ATOM 2788  O O   . GLU A 1 421 ? -6.903  -5.711  -1.880  1.00 49.46  ? 421 GLU A O   1 
ATOM 2789  C CB  . GLU A 1 421 ? -5.669  -3.473  -3.729  1.00 58.22  ? 421 GLU A CB  1 
ATOM 2790  C CG  . GLU A 1 421 ? -4.611  -3.253  -4.799  1.00 70.64  ? 421 GLU A CG  1 
ATOM 2791  C CD  . GLU A 1 421 ? -3.462  -4.248  -4.894  1.00 72.79  ? 421 GLU A CD  1 
ATOM 2792  O OE1 . GLU A 1 421 ? -3.690  -5.459  -4.711  1.00 65.49  ? 421 GLU A OE1 1 
ATOM 2793  O OE2 . GLU A 1 421 ? -2.333  -3.807  -5.175  1.00 72.13  ? 421 GLU A OE2 1 
ATOM 2794  N N   . GLN A 1 422 ? -8.720  -4.774  -2.835  1.00 54.84  ? 422 GLN A N   1 
ATOM 2795  C CA  . GLN A 1 422 ? -9.608  -5.067  -1.691  1.00 59.22  ? 422 GLN A CA  1 
ATOM 2796  C C   . GLN A 1 422 ? -9.729  -6.571  -1.492  1.00 59.53  ? 422 GLN A C   1 
ATOM 2797  O O   . GLN A 1 422 ? -9.741  -6.991  -0.342  1.00 57.60  ? 422 GLN A O   1 
ATOM 2798  C CB  . GLN A 1 422 ? -10.995 -4.473  -1.905  1.00 65.34  ? 422 GLN A CB  1 
ATOM 2799  C CG  . GLN A 1 422 ? -10.989 -3.141  -2.642  1.00 74.53  ? 422 GLN A CG  1 
ATOM 2800  C CD  . GLN A 1 422 ? -10.334 -2.026  -1.863  1.00 74.16  ? 422 GLN A CD  1 
ATOM 2801  O OE1 . GLN A 1 422 ? -10.324 -2.022  -0.634  1.00 80.54  ? 422 GLN A OE1 1 
ATOM 2802  N NE2 . GLN A 1 422 ? -9.790  -1.058  -2.582  1.00 55.56  ? 422 GLN A NE2 1 
ATOM 2803  N N   . GLU A 1 423 ? -9.832  -7.345  -2.569  1.00 55.30  ? 423 GLU A N   1 
ATOM 2804  C CA  . GLU A 1 423 ? -10.098 -8.795  -2.388  1.00 52.28  ? 423 GLU A CA  1 
ATOM 2805  C C   . GLU A 1 423 ? -8.956  -9.478  -1.647  1.00 47.47  ? 423 GLU A C   1 
ATOM 2806  O O   . GLU A 1 423 ? -9.247  -10.229 -0.717  1.00 42.20  ? 423 GLU A O   1 
ATOM 2807  C CB  . GLU A 1 423 ? -10.445 -9.459  -3.723  1.00 58.30  ? 423 GLU A CB  1 
ATOM 2808  C CG  . GLU A 1 423 ? -9.817  -8.815  -4.947  1.00 69.02  ? 423 GLU A CG  1 
ATOM 2809  C CD  . GLU A 1 423 ? -10.276 -9.426  -6.264  1.00 69.95  ? 423 GLU A CD  1 
ATOM 2810  O OE1 . GLU A 1 423 ? -11.203 -10.260 -6.237  1.00 69.19  ? 423 GLU A OE1 1 
ATOM 2811  O OE2 . GLU A 1 423 ? -9.709  -9.066  -7.317  1.00 56.79  ? 423 GLU A OE2 1 
ATOM 2812  N N   . ILE A 1 424 ? -7.720  -9.206  -2.036  1.00 50.28  ? 424 ILE A N   1 
ATOM 2813  C CA  . ILE A 1 424 ? -6.540  -9.754  -1.313  1.00 51.34  ? 424 ILE A CA  1 
ATOM 2814  C C   . ILE A 1 424 ? -6.444  -9.104  0.069   1.00 48.18  ? 424 ILE A C   1 
ATOM 2815  O O   . ILE A 1 424 ? -6.008  -9.780  1.001   1.00 48.70  ? 424 ILE A O   1 
ATOM 2816  C CB  . ILE A 1 424 ? -5.267  -9.634  -2.164  1.00 53.50  ? 424 ILE A CB  1 
ATOM 2817  C CG1 . ILE A 1 424 ? -5.551  -10.006 -3.620  1.00 56.53  ? 424 ILE A CG1 1 
ATOM 2818  C CG2 . ILE A 1 424 ? -4.145  -10.476 -1.584  1.00 51.56  ? 424 ILE A CG2 1 
ATOM 2819  C CD1 . ILE A 1 424 ? -4.315  -10.148 -4.467  1.00 58.99  ? 424 ILE A CD1 1 
ATOM 2820  N N   . ASP A 1 425 ? -6.815  -7.831  0.184   1.00 45.97  ? 425 ASP A N   1 
ATOM 2821  C CA  . ASP A 1 425 ? -6.813  -7.146  1.501   1.00 50.32  ? 425 ASP A CA  1 
ATOM 2822  C C   . ASP A 1 425 ? -7.807  -7.823  2.444   1.00 56.89  ? 425 ASP A C   1 
ATOM 2823  O O   . ASP A 1 425 ? -7.449  -8.044  3.604   1.00 59.55  ? 425 ASP A O   1 
ATOM 2824  C CB  . ASP A 1 425 ? -7.180  -5.673  1.342   1.00 52.12  ? 425 ASP A CB  1 
ATOM 2825  C CG  . ASP A 1 425 ? -6.053  -4.786  0.848   1.00 68.20  ? 425 ASP A CG  1 
ATOM 2826  O OD1 . ASP A 1 425 ? -5.026  -5.328  0.419   1.00 68.82  ? 425 ASP A OD1 1 
ATOM 2827  O OD2 . ASP A 1 425 ? -6.223  -3.555  0.894   1.00 69.28  ? 425 ASP A OD2 1 
ATOM 2828  N N   . ARG A 1 426 ? -9.008  -8.125  1.962   1.00 50.94  ? 426 ARG A N   1 
ATOM 2829  C CA  . ARG A 1 426 ? -10.024 -8.843  2.770   1.00 50.34  ? 426 ARG A CA  1 
ATOM 2830  C C   . ARG A 1 426 ? -9.539  -10.258 3.069   1.00 50.40  ? 426 ARG A C   1 
ATOM 2831  O O   . ARG A 1 426 ? -9.882  -10.788 4.129   1.00 51.75  ? 426 ARG A O   1 
ATOM 2832  C CB  . ARG A 1 426 ? -11.368 -8.813  2.043   1.00 53.73  ? 426 ARG A CB  1 
ATOM 2833  C CG  . ARG A 1 426 ? -11.963 -7.419  1.909   1.00 60.25  ? 426 ARG A CG  1 
ATOM 2834  C CD  . ARG A 1 426 ? -13.348 -7.434  1.297   1.00 62.50  ? 426 ARG A CD  1 
ATOM 2835  N NE  . ARG A 1 426 ? -13.411 -8.343  0.162   1.00 77.33  ? 426 ARG A NE  1 
ATOM 2836  C CZ  . ARG A 1 426 ? -14.494 -8.552  -0.574  1.00 76.06  ? 426 ARG A CZ  1 
ATOM 2837  N NH1 . ARG A 1 426 ? -15.616 -7.910  -0.296  1.00 76.39  ? 426 ARG A NH1 1 
ATOM 2838  N NH2 . ARG A 1 426 ? -14.451 -9.402  -1.586  1.00 60.18  ? 426 ARG A NH2 1 
ATOM 2839  N N   . ALA A 1 427 ? -8.848  -10.878 2.117   1.00 50.70  ? 427 ALA A N   1 
ATOM 2840  C CA  . ALA A 1 427 ? -8.292  -12.230 2.323   1.00 48.59  ? 427 ALA A CA  1 
ATOM 2841  C C   . ALA A 1 427 ? -7.248  -12.171 3.425   1.00 53.58  ? 427 ALA A C   1 
ATOM 2842  O O   . ALA A 1 427 ? -7.231  -13.070 4.263   1.00 54.93  ? 427 ALA A O   1 
ATOM 2843  C CB  . ALA A 1 427 ? -7.657  -12.697 1.051   1.00 47.71  ? 427 ALA A CB  1 
ATOM 2844  N N   . VAL A 1 428 ? -6.409  -11.138 3.403   1.00 47.75  ? 428 VAL A N   1 
ATOM 2845  C CA  . VAL A 1 428 ? -5.375  -11.017 4.426   1.00 52.61  ? 428 VAL A CA  1 
ATOM 2846  C C   . VAL A 1 428 ? -5.999  -10.784 5.793   1.00 52.42  ? 428 VAL A C   1 
ATOM 2847  O O   . VAL A 1 428 ? -5.568  -11.370 6.794   1.00 49.83  ? 428 VAL A O   1 
ATOM 2848  C CB  . VAL A 1 428 ? -4.385  -9.898  4.062   1.00 53.72  ? 428 VAL A CB  1 
ATOM 2849  C CG1 . VAL A 1 428 ? -3.488  -9.572  5.249   1.00 52.64  ? 428 VAL A CG1 1 
ATOM 2850  C CG2 . VAL A 1 428 ? -3.551  -10.307 2.875   1.00 52.90  ? 428 VAL A CG2 1 
ATOM 2851  N N   . GLU A 1 429 ? -7.010  -9.918  5.868   1.00 46.99  ? 429 GLU A N   1 
ATOM 2852  C CA  . GLU A 1 429 ? -7.623  -9.685  7.170   1.00 47.31  ? 429 GLU A CA  1 
ATOM 2853  C C   . GLU A 1 429 ? -8.351  -10.932 7.668   1.00 58.00  ? 429 GLU A C   1 
ATOM 2854  O O   . GLU A 1 429 ? -8.362  -11.193 8.874   1.00 62.06  ? 429 GLU A O   1 
ATOM 2855  C CB  . GLU A 1 429 ? -8.556  -8.474  7.135   1.00 53.94  ? 429 GLU A CB  1 
ATOM 2856  C CG  . GLU A 1 429 ? -9.818  -8.637  6.323   1.00 60.22  ? 429 GLU A CG  1 
ATOM 2857  C CD  . GLU A 1 429 ? -10.663 -7.379  6.308   1.00 69.44  ? 429 GLU A CD  1 
ATOM 2858  O OE1 . GLU A 1 429 ? -10.567 -6.575  7.262   1.00 73.35  ? 429 GLU A OE1 1 
ATOM 2859  O OE2 . GLU A 1 429 ? -11.422 -7.188  5.336   1.00 53.87  ? 429 GLU A OE2 1 
ATOM 2860  N N   . GLU A 1 430 ? -8.909  -11.747 6.766   1.00 55.12  ? 430 GLU A N   1 
ATOM 2861  C CA  . GLU A 1 430 ? -9.526  -12.989 7.223   1.00 52.76  ? 430 GLU A CA  1 
ATOM 2862  C C   . GLU A 1 430 ? -8.480  -14.015 7.650   1.00 56.40  ? 430 GLU A C   1 
ATOM 2863  O O   . GLU A 1 430 ? -8.712  -14.766 8.605   1.00 59.08  ? 430 GLU A O   1 
ATOM 2864  C CB  . GLU A 1 430 ? -10.449 -13.572 6.149   1.00 56.88  ? 430 GLU A CB  1 
ATOM 2865  C CG  . GLU A 1 430 ? -11.605 -14.393 6.726   1.00 64.17  ? 430 GLU A CG  1 
ATOM 2866  C CD  . GLU A 1 430 ? -12.875 -14.309 5.886   1.00 60.07  ? 430 GLU A CD  1 
ATOM 2867  O OE1 . GLU A 1 430 ? -12.769 -14.079 4.659   1.00 58.66  ? 430 GLU A OE1 1 
ATOM 2868  O OE2 . GLU A 1 430 ? -13.983 -14.474 6.452   1.00 54.79  ? 430 GLU A OE2 1 
ATOM 2869  N N   . LEU A 1 431 ? -7.325  -14.051 6.981   1.00 55.93  ? 431 LEU A N   1 
ATOM 2870  C CA  . LEU A 1 431 ? -6.244  -14.920 7.449   1.00 52.17  ? 431 LEU A CA  1 
ATOM 2871  C C   . LEU A 1 431 ? -5.772  -14.510 8.841   1.00 55.64  ? 431 LEU A C   1 
ATOM 2872  O O   . LEU A 1 431 ? -5.546  -15.362 9.711   1.00 56.38  ? 431 LEU A O   1 
ATOM 2873  C CB  . LEU A 1 431 ? -5.080  -14.895 6.459   1.00 46.21  ? 431 LEU A CB  1 
ATOM 2874  C CG  . LEU A 1 431 ? -5.262  -15.652 5.140   1.00 41.99  ? 431 LEU A CG  1 
ATOM 2875  C CD1 . LEU A 1 431 ? -4.193  -15.262 4.125   1.00 42.46  ? 431 LEU A CD1 1 
ATOM 2876  C CD2 . LEU A 1 431 ? -5.250  -17.157 5.370   1.00 41.35  ? 431 LEU A CD2 1 
ATOM 2877  N N   . VAL A 1 432 ? -5.623  -13.203 9.067   1.00 53.67  ? 432 VAL A N   1 
ATOM 2878  C CA  . VAL A 1 432 ? -5.260  -12.715 10.395  1.00 61.42  ? 432 VAL A CA  1 
ATOM 2879  C C   . VAL A 1 432 ? -6.345  -13.056 11.406  1.00 63.50  ? 432 VAL A C   1 
ATOM 2880  O O   . VAL A 1 432 ? -6.055  -13.344 12.574  1.00 61.60  ? 432 VAL A O   1 
ATOM 2881  C CB  . VAL A 1 432 ? -4.978  -11.200 10.347  1.00 60.44  ? 432 VAL A CB  1 
ATOM 2882  C CG1 . VAL A 1 432 ? -4.681  -10.658 11.739  1.00 63.18  ? 432 VAL A CG1 1 
ATOM 2883  C CG2 . VAL A 1 432 ? -3.819  -10.911 9.411   1.00 58.06  ? 432 VAL A CG2 1 
ATOM 2884  N N   . GLN A 1 433 ? -7.611  -13.030 10.981  1.00 59.45  ? 433 GLN A N   1 
ATOM 2885  C CA  . GLN A 1 433 ? -8.689  -13.477 11.854  1.00 60.29  ? 433 GLN A CA  1 
ATOM 2886  C C   . GLN A 1 433 ? -8.518  -14.945 12.225  1.00 62.69  ? 433 GLN A C   1 
ATOM 2887  O O   . GLN A 1 433 ? -8.744  -15.331 13.376  1.00 67.85  ? 433 GLN A O   1 
ATOM 2888  C CB  . GLN A 1 433 ? -10.043 -13.242 11.183  1.00 62.34  ? 433 GLN A CB  1 
ATOM 2889  C CG  . GLN A 1 433 ? -11.240 -13.639 12.033  1.00 63.68  ? 433 GLN A CG  1 
ATOM 2890  C CD  . GLN A 1 433 ? -12.563 -13.343 11.351  1.00 76.40  ? 433 GLN A CD  1 
ATOM 2891  O OE1 . GLN A 1 433 ? -12.597 -12.832 10.231  1.00 65.36  ? 433 GLN A OE1 1 
ATOM 2892  N NE2 . GLN A 1 433 ? -13.663 -13.662 12.026  1.00 79.96  ? 433 GLN A NE2 1 
ATOM 2893  N N   . ILE A 1 434 ? -8.122  -15.780 11.263  1.00 55.73  ? 434 ILE A N   1 
ATOM 2894  C CA  . ILE A 1 434 ? -7.860  -17.187 11.570  1.00 55.76  ? 434 ILE A CA  1 
ATOM 2895  C C   . ILE A 1 434 ? -6.754  -17.293 12.616  1.00 56.70  ? 434 ILE A C   1 
ATOM 2896  O O   . ILE A 1 434 ? -6.872  -18.028 13.608  1.00 54.76  ? 434 ILE A O   1 
ATOM 2897  C CB  . ILE A 1 434 ? -7.500  -17.973 10.297  1.00 52.68  ? 434 ILE A CB  1 
ATOM 2898  C CG1 . ILE A 1 434 ? -8.609  -17.856 9.251   1.00 51.36  ? 434 ILE A CG1 1 
ATOM 2899  C CG2 . ILE A 1 434 ? -7.241  -19.435 10.631  1.00 33.46  ? 434 ILE A CG2 1 
ATOM 2900  C CD1 . ILE A 1 434 ? -9.990  -18.108 9.801   1.00 57.28  ? 434 ILE A CD1 1 
ATOM 2901  N N   . CYS A 1 435 ? -5.671  -16.539 12.413  1.00 57.54  ? 435 CYS A N   1 
ATOM 2902  C CA  . CYS A 1 435 ? -4.544  -16.607 13.340  1.00 62.18  ? 435 CYS A CA  1 
ATOM 2903  C C   . CYS A 1 435 ? -4.943  -16.165 14.747  1.00 64.78  ? 435 CYS A C   1 
ATOM 2904  O O   . CYS A 1 435 ? -4.530  -16.780 15.735  1.00 60.37  ? 435 CYS A O   1 
ATOM 2905  C CB  . CYS A 1 435 ? -3.379  -15.769 12.814  1.00 61.68  ? 435 CYS A CB  1 
ATOM 2906  S SG  . CYS A 1 435 ? -2.491  -16.535 11.436  1.00 50.94  ? 435 CYS A SG  1 
ATOM 2907  N N   . LYS A 1 436 ? -5.755  -15.109 14.858  1.00 62.09  ? 436 LYS A N   1 
ATOM 2908  C CA  . LYS A 1 436 ? -6.169  -14.657 16.186  1.00 61.99  ? 436 LYS A CA  1 
ATOM 2909  C C   . LYS A 1 436 ? -7.196  -15.597 16.805  1.00 61.62  ? 436 LYS A C   1 
ATOM 2910  O O   . LYS A 1 436 ? -7.280  -15.696 18.034  1.00 68.44  ? 436 LYS A O   1 
ATOM 2911  C CB  . LYS A 1 436 ? -6.721  -13.230 16.125  1.00 66.33  ? 436 LYS A CB  1 
ATOM 2912  C CG  . LYS A 1 436 ? -8.080  -13.119 15.465  1.00 70.67  ? 436 LYS A CG  1 
ATOM 2913  C CD  . LYS A 1 436 ? -8.730  -11.771 15.711  1.00 77.56  ? 436 LYS A CD  1 
ATOM 2914  C CE  . LYS A 1 436 ? -10.055 -11.673 14.957  1.00 67.63  ? 436 LYS A CE  1 
ATOM 2915  N NZ  . LYS A 1 436 ? -10.978 -12.794 15.296  1.00 54.45  ? 436 LYS A NZ  1 
ATOM 2916  N N   . LYS A 1 437 ? -7.981  -16.328 16.030  1.00 65.34  ? 437 LYS A N   1 
ATOM 2917  C CA  . LYS A 1 437 ? -8.913  -17.259 16.709  1.00 59.07  ? 437 LYS A CA  1 
ATOM 2918  C C   . LYS A 1 437 ? -8.080  -18.378 17.318  1.00 65.16  ? 437 LYS A C   1 
ATOM 2919  O O   . LYS A 1 437 ? -8.595  -19.095 18.183  1.00 73.30  ? 437 LYS A O   1 
ATOM 2920  C CB  . LYS A 1 437 ? -9.945  -17.824 15.735  1.00 72.70  ? 437 LYS A CB  1 
ATOM 2921  C CG  . LYS A 1 437 ? -11.129 -18.549 16.362  1.00 73.57  ? 437 LYS A CG  1 
ATOM 2922  C CD  . LYS A 1 437 ? -11.979 -19.291 15.355  1.00 72.81  ? 437 LYS A CD  1 
ATOM 2923  C CE  . LYS A 1 437 ? -11.209 -20.351 14.597  1.00 75.18  ? 437 LYS A CE  1 
ATOM 2924  N NZ  . LYS A 1 437 ? -10.726 -21.430 15.490  1.00 88.32  ? 437 LYS A NZ  1 
ATOM 2925  N N   . LYS A 1 438 ? -6.831  -18.505 16.880  1.00 69.70  ? 438 LYS A N   1 
ATOM 2926  C CA  . LYS A 1 438 ? -5.955  -19.595 17.385  1.00 70.50  ? 438 LYS A CA  1 
ATOM 2927  C C   . LYS A 1 438 ? -5.155  -19.095 18.586  1.00 64.63  ? 438 LYS A C   1 
ATOM 2928  O O   . LYS A 1 438 ? -4.409  -19.888 19.170  1.00 64.30  ? 438 LYS A O   1 
ATOM 2929  C CB  . LYS A 1 438 ? -5.106  -20.181 16.256  1.00 61.63  ? 438 LYS A CB  1 
ATOM 2930  C CG  . LYS A 1 438 ? -5.865  -21.024 15.241  1.00 67.44  ? 438 LYS A CG  1 
ATOM 2931  C CD  . LYS A 1 438 ? -6.134  -22.428 15.730  1.00 72.13  ? 438 LYS A CD  1 
ATOM 2932  C CE  . LYS A 1 438 ? -4.866  -23.175 16.083  1.00 58.69  ? 438 LYS A CE  1 
ATOM 2933  N NZ  . LYS A 1 438 ? -5.140  -24.588 16.431  1.00 62.27  ? 438 LYS A NZ  1 
ATOM 2934  N N   . LYS A 1 439 ? -5.315  -17.826 18.944  1.00 64.72  ? 439 LYS A N   1 
ATOM 2935  C CA  . LYS A 1 439 ? -4.666  -17.317 20.172  1.00 65.57  ? 439 LYS A CA  1 
ATOM 2936  C C   . LYS A 1 439 ? -5.581  -17.694 21.330  1.00 77.70  ? 439 LYS A C   1 
ATOM 2937  O O   . LYS A 1 439 ? -6.226  -16.798 21.886  1.00 81.28  ? 439 LYS A O   1 
ATOM 2938  C CB  . LYS A 1 439 ? -4.496  -15.801 20.092  1.00 69.60  ? 439 LYS A CB  1 
ATOM 2939  C CG  . LYS A 1 439 ? -3.351  -15.325 19.211  1.00 71.73  ? 439 LYS A CG  1 
ATOM 2940  C CD  . LYS A 1 439 ? -2.017  -15.895 19.639  1.00 79.67  ? 439 LYS A CD  1 
ATOM 2941  C CE  . LYS A 1 439 ? -1.647  -15.548 21.065  1.00 68.83  ? 439 LYS A CE  1 
ATOM 2942  N NZ  . LYS A 1 439 ? -0.442  -16.286 21.508  1.00 77.54  ? 439 LYS A NZ  1 
ATOM 2943  N N   . ASP A 1 440 ? -5.657  -18.987 21.641  1.00 84.16  ? 440 ASP A N   1 
ATOM 2944  C CA  . ASP A 1 440 ? -6.480  -19.476 22.772  1.00 76.75  ? 440 ASP A CA  1 
ATOM 2945  C C   . ASP A 1 440 ? -5.511  -20.054 23.801  1.00 85.16  ? 440 ASP A C   1 
ATOM 2946  O O   . ASP A 1 440 ? -4.655  -20.853 23.400  1.00 86.20  ? 440 ASP A O   1 
ATOM 2947  C CB  . ASP A 1 440 ? -7.543  -20.472 22.305  1.00 76.93  ? 440 ASP A CB  1 
ATOM 2948  C CG  . ASP A 1 440 ? -7.128  -21.393 21.167  1.00 89.81  ? 440 ASP A CG  1 
ATOM 2949  O OD1 . ASP A 1 440 ? -5.951  -21.792 21.125  1.00 94.26  ? 440 ASP A OD1 1 
ATOM 2950  O OD2 . ASP A 1 440 ? -7.993  -21.709 20.330  1.00 82.63  ? 440 ASP A OD2 1 
ATOM 2951  N N   . GLU A 1 441 ? -5.625  -19.638 25.063  1.00 85.75  ? 441 GLU A N   1 
ATOM 2952  C CA  . GLU A 1 441 ? -4.664  -20.071 26.105  1.00 86.07  ? 441 GLU A CA  1 
ATOM 2953  C C   . GLU A 1 441 ? -3.243  -19.712 25.675  1.00 95.87  ? 441 GLU A C   1 
ATOM 2954  O O   . GLU A 1 441 ? -2.366  -20.575 25.837  1.00 100.08 ? 441 GLU A O   1 
ATOM 2955  C CB  . GLU A 1 441 ? -4.789  -21.565 26.380  1.00 93.17  ? 441 GLU A CB  1 
ATOM 2956  C CG  . GLU A 1 441 ? -6.222  -22.031 26.585  1.00 97.93  ? 441 GLU A CG  1 
ATOM 2957  C CD  . GLU A 1 441 ? -6.894  -21.579 27.870  1.00 74.28  ? 441 GLU A CD  1 
ATOM 2958  O OE1 . GLU A 1 441 ? -7.239  -20.385 27.973  1.00 67.28  ? 441 GLU A OE1 1 
ATOM 2959  O OE2 . GLU A 1 441 ? -7.081  -22.431 28.761  1.00 45.31  ? 441 GLU A OE2 1 
ATOM 2960  N N   . GLN A 1 442 ? -3.034  -18.514 25.115  1.00 96.06  ? 442 GLN A N   1 
ATOM 2961  C CA  . GLN A 1 442 ? -1.670  -18.025 24.769  1.00 88.70  ? 442 GLN A CA  1 
ATOM 2962  C C   . GLN A 1 442 ? -0.928  -19.032 23.886  1.00 89.71  ? 442 GLN A C   1 
ATOM 2963  O O   . GLN A 1 442 ? 0.046   -18.599 23.241  1.00 86.54  ? 442 GLN A O   1 
ATOM 2964  C CB  . GLN A 1 442 ? -0.876  -17.712 26.039  1.00 82.14  ? 442 GLN A CB  1 
ATOM 2965  C CG  . GLN A 1 442 ? -1.507  -16.634 26.907  1.00 82.05  ? 442 GLN A CG  1 
ATOM 2966  C CD  . GLN A 1 442 ? -2.194  -17.208 28.122  1.00 86.28  ? 442 GLN A CD  1 
ATOM 2967  O OE1 . GLN A 1 442 ? -2.036  -18.379 28.454  1.00 85.50  ? 442 GLN A OE1 1 
ATOM 2968  N NE2 . GLN A 1 442 ? -2.965  -16.377 28.803  1.00 89.09  ? 442 GLN A NE2 1 
ATOM 2969  N N   . ILE B 1 8   ? -35.118 -13.456 23.371  1.00 68.14  ? 8   ILE B N   1 
ATOM 2970  C CA  . ILE B 1 8   ? -35.957 -12.560 24.156  1.00 66.22  ? 8   ILE B CA  1 
ATOM 2971  C C   . ILE B 1 8   ? -36.856 -13.351 25.111  1.00 60.08  ? 8   ILE B C   1 
ATOM 2972  O O   . ILE B 1 8   ? -37.037 -12.957 26.260  1.00 62.76  ? 8   ILE B O   1 
ATOM 2973  C CB  . ILE B 1 8   ? -36.800 -11.645 23.239  1.00 70.67  ? 8   ILE B CB  1 
ATOM 2974  C CG1 . ILE B 1 8   ? -35.892 -10.853 22.292  1.00 64.04  ? 8   ILE B CG1 1 
ATOM 2975  C CG2 . ILE B 1 8   ? -37.650 -10.691 24.066  1.00 67.62  ? 8   ILE B CG2 1 
ATOM 2976  C CD1 . ILE B 1 8   ? -34.949 -9.901  22.997  1.00 56.23  ? 8   ILE B CD1 1 
ATOM 2977  N N   . SER B 1 9   ? -37.410 -14.465 24.640  1.00 50.63  ? 9   SER B N   1 
ATOM 2978  C CA  . SER B 1 9   ? -38.299 -15.291 25.446  1.00 51.34  ? 9   SER B CA  1 
ATOM 2979  C C   . SER B 1 9   ? -37.535 -16.449 26.073  1.00 52.34  ? 9   SER B C   1 
ATOM 2980  O O   . SER B 1 9   ? -36.735 -17.116 25.406  1.00 47.54  ? 9   SER B O   1 
ATOM 2981  C CB  . SER B 1 9   ? -39.457 -15.837 24.608  1.00 44.81  ? 9   SER B CB  1 
ATOM 2982  O OG  . SER B 1 9   ? -39.018 -16.883 23.761  1.00 39.58  ? 9   SER B OG  1 
ATOM 2983  N N   . ILE B 1 10  ? -37.791 -16.694 27.358  1.00 41.08  ? 10  ILE B N   1 
ATOM 2984  C CA  . ILE B 1 10  ? -37.108 -17.728 28.126  1.00 43.13  ? 10  ILE B CA  1 
ATOM 2985  C C   . ILE B 1 10  ? -38.145 -18.569 28.860  1.00 41.62  ? 10  ILE B C   1 
ATOM 2986  O O   . ILE B 1 10  ? -39.168 -18.045 29.319  1.00 44.19  ? 10  ILE B O   1 
ATOM 2987  C CB  . ILE B 1 10  ? -36.099 -17.121 29.129  1.00 45.17  ? 10  ILE B CB  1 
ATOM 2988  C CG1 . ILE B 1 10  ? -35.197 -16.094 28.442  1.00 41.60  ? 10  ILE B CG1 1 
ATOM 2989  C CG2 . ILE B 1 10  ? -35.247 -18.210 29.767  1.00 38.08  ? 10  ILE B CG2 1 
ATOM 2990  C CD1 . ILE B 1 10  ? -34.186 -15.459 29.369  1.00 35.50  ? 10  ILE B CD1 1 
ATOM 2991  N N   . ALA B 1 11  ? -37.880 -19.869 28.968  1.00 40.57  ? 11  ALA B N   1 
ATOM 2992  C CA  . ALA B 1 11  ? -38.711 -20.796 29.723  1.00 40.53  ? 11  ALA B CA  1 
ATOM 2993  C C   . ALA B 1 11  ? -37.880 -21.439 30.824  1.00 37.59  ? 11  ALA B C   1 
ATOM 2994  O O   . ALA B 1 11  ? -36.736 -21.841 30.595  1.00 47.93  ? 11  ALA B O   1 
ATOM 2995  C CB  . ALA B 1 11  ? -39.305 -21.876 28.812  1.00 37.44  ? 11  ALA B CB  1 
ATOM 2996  N N   . LEU B 1 12  ? -38.456 -21.532 32.020  1.00 38.39  ? 12  LEU B N   1 
ATOM 2997  C CA  . LEU B 1 12  ? -37.771 -22.048 33.197  1.00 43.48  ? 12  LEU B CA  1 
ATOM 2998  C C   . LEU B 1 12  ? -38.446 -23.327 33.665  1.00 42.51  ? 12  LEU B C   1 
ATOM 2999  O O   . LEU B 1 12  ? -39.679 -23.391 33.760  1.00 48.12  ? 12  LEU B O   1 
ATOM 3000  C CB  . LEU B 1 12  ? -37.759 -21.015 34.329  1.00 39.27  ? 12  LEU B CB  1 
ATOM 3001  C CG  . LEU B 1 12  ? -36.496 -20.161 34.452  1.00 35.29  ? 12  LEU B CG  1 
ATOM 3002  C CD1 . LEU B 1 12  ? -36.204 -19.453 33.145  1.00 38.99  ? 12  LEU B CD1 1 
ATOM 3003  C CD2 . LEU B 1 12  ? -36.621 -19.161 35.591  1.00 37.90  ? 12  LEU B CD2 1 
ATOM 3004  N N   . LEU B 1 13  ? -37.634 -24.345 33.949  1.00 39.37  ? 13  LEU B N   1 
ATOM 3005  C CA  . LEU B 1 13  ? -38.110 -25.641 34.427  1.00 38.75  ? 13  LEU B CA  1 
ATOM 3006  C C   . LEU B 1 13  ? -37.327 -26.005 35.683  1.00 46.25  ? 13  LEU B C   1 
ATOM 3007  O O   . LEU B 1 13  ? -36.341 -26.752 35.622  1.00 46.12  ? 13  LEU B O   1 
ATOM 3008  C CB  . LEU B 1 13  ? -37.960 -26.720 33.356  1.00 44.25  ? 13  LEU B CB  1 
ATOM 3009  C CG  . LEU B 1 13  ? -38.470 -28.112 33.723  1.00 55.16  ? 13  LEU B CG  1 
ATOM 3010  C CD1 . LEU B 1 13  ? -39.982 -28.202 33.552  1.00 51.09  ? 13  LEU B CD1 1 
ATOM 3011  C CD2 . LEU B 1 13  ? -37.761 -29.176 32.901  1.00 61.24  ? 13  LEU B CD2 1 
ATOM 3012  N N   . PRO B 1 14  ? -37.734 -25.482 36.836  1.00 37.11  ? 14  PRO B N   1 
ATOM 3013  C CA  . PRO B 1 14  ? -37.097 -25.887 38.094  1.00 36.27  ? 14  PRO B CA  1 
ATOM 3014  C C   . PRO B 1 14  ? -37.491 -27.306 38.471  1.00 36.30  ? 14  PRO B C   1 
ATOM 3015  O O   . PRO B 1 14  ? -38.313 -27.955 37.821  1.00 42.53  ? 14  PRO B O   1 
ATOM 3016  C CB  . PRO B 1 14  ? -37.634 -24.871 39.103  1.00 38.61  ? 14  PRO B CB  1 
ATOM 3017  C CG  . PRO B 1 14  ? -38.945 -24.440 38.530  1.00 43.62  ? 14  PRO B CG  1 
ATOM 3018  C CD  . PRO B 1 14  ? -38.767 -24.455 37.042  1.00 35.73  ? 14  PRO B CD  1 
ATOM 3019  N N   . PHE B 1 15  ? -36.884 -27.789 39.549  1.00 38.95  ? 15  PHE B N   1 
ATOM 3020  C CA  . PHE B 1 15  ? -37.223 -29.106 40.061  1.00 46.30  ? 15  PHE B CA  1 
ATOM 3021  C C   . PHE B 1 15  ? -38.400 -29.007 41.030  1.00 49.14  ? 15  PHE B C   1 
ATOM 3022  O O   . PHE B 1 15  ? -38.811 -27.919 41.447  1.00 47.40  ? 15  PHE B O   1 
ATOM 3023  C CB  . PHE B 1 15  ? -36.009 -29.752 40.728  1.00 37.57  ? 15  PHE B CB  1 
ATOM 3024  C CG  . PHE B 1 15  ? -36.171 -31.222 40.975  1.00 35.62  ? 15  PHE B CG  1 
ATOM 3025  C CD1 . PHE B 1 15  ? -36.712 -32.044 40.000  1.00 52.18  ? 15  PHE B CD1 1 
ATOM 3026  C CD2 . PHE B 1 15  ? -35.781 -31.784 42.177  1.00 46.91  ? 15  PHE B CD2 1 
ATOM 3027  C CE1 . PHE B 1 15  ? -36.869 -33.398 40.223  1.00 63.21  ? 15  PHE B CE1 1 
ATOM 3028  C CE2 . PHE B 1 15  ? -35.930 -33.140 42.405  1.00 47.66  ? 15  PHE B CE2 1 
ATOM 3029  C CZ  . PHE B 1 15  ? -36.477 -33.947 41.427  1.00 63.30  ? 15  PHE B CZ  1 
ATOM 3030  N N   . LEU B 1 16  ? -38.952 -30.164 41.386  1.00 54.99  ? 16  LEU B N   1 
ATOM 3031  C CA  . LEU B 1 16  ? -40.157 -30.233 42.214  1.00 50.35  ? 16  LEU B CA  1 
ATOM 3032  C C   . LEU B 1 16  ? -39.803 -30.163 43.701  1.00 54.85  ? 16  LEU B C   1 
ATOM 3033  O O   . LEU B 1 16  ? -40.031 -31.090 44.479  1.00 62.48  ? 16  LEU B O   1 
ATOM 3034  C CB  . LEU B 1 16  ? -40.948 -31.493 41.890  1.00 51.05  ? 16  LEU B CB  1 
ATOM 3035  C CG  . LEU B 1 16  ? -42.084 -31.314 40.885  1.00 51.97  ? 16  LEU B CG  1 
ATOM 3036  C CD1 . LEU B 1 16  ? -41.634 -30.471 39.705  1.00 51.40  ? 16  LEU B CD1 1 
ATOM 3037  C CD2 . LEU B 1 16  ? -42.589 -32.667 40.416  1.00 57.81  ? 16  LEU B CD2 1 
ATOM 3038  N N   . ALA B 1 17  ? -39.239 -29.024 44.086  1.00 58.99  ? 17  ALA B N   1 
ATOM 3039  C CA  . ALA B 1 17  ? -38.879 -28.772 45.473  1.00 53.50  ? 17  ALA B CA  1 
ATOM 3040  C C   . ALA B 1 17  ? -38.896 -27.271 45.704  1.00 61.61  ? 17  ALA B C   1 
ATOM 3041  O O   . ALA B 1 17  ? -38.328 -26.514 44.911  1.00 63.88  ? 17  ALA B O   1 
ATOM 3042  C CB  . ALA B 1 17  ? -37.499 -29.353 45.800  1.00 57.22  ? 17  ALA B CB  1 
ATOM 3043  N N   . HIS B 1 18  ? -39.550 -26.849 46.788  1.00 62.71  ? 18  HIS B N   1 
ATOM 3044  C CA  . HIS B 1 18  ? -39.658 -25.425 47.081  1.00 74.46  ? 18  HIS B CA  1 
ATOM 3045  C C   . HIS B 1 18  ? -38.303 -24.779 47.335  1.00 72.33  ? 18  HIS B C   1 
ATOM 3046  O O   . HIS B 1 18  ? -38.185 -23.552 47.240  1.00 68.30  ? 18  HIS B O   1 
ATOM 3047  C CB  . HIS B 1 18  ? -40.587 -25.205 48.277  1.00 80.91  ? 18  HIS B CB  1 
ATOM 3048  C CG  . HIS B 1 18  ? -42.023 -25.509 47.984  1.00 95.36  ? 18  HIS B CG  1 
ATOM 3049  N ND1 . HIS B 1 18  ? -42.671 -26.613 48.494  1.00 107.61 ? 18  HIS B ND1 1 
ATOM 3050  C CD2 . HIS B 1 18  ? -42.930 -24.862 47.214  1.00 85.16  ? 18  HIS B CD2 1 
ATOM 3051  C CE1 . HIS B 1 18  ? -43.920 -26.627 48.062  1.00 100.99 ? 18  HIS B CE1 1 
ATOM 3052  N NE2 . HIS B 1 18  ? -44.103 -25.573 47.283  1.00 89.91  ? 18  HIS B NE2 1 
ATOM 3053  N N   . GLY B 1 19  ? -37.276 -25.574 47.650  1.00 69.63  ? 19  GLY B N   1 
ATOM 3054  C CA  . GLY B 1 19  ? -35.930 -25.039 47.734  1.00 75.49  ? 19  GLY B CA  1 
ATOM 3055  C C   . GLY B 1 19  ? -35.366 -24.594 46.399  1.00 69.22  ? 19  GLY B C   1 
ATOM 3056  O O   . GLY B 1 19  ? -34.419 -23.800 46.372  1.00 64.09  ? 19  GLY B O   1 
ATOM 3057  N N   . HIS B 1 20  ? -35.923 -25.090 45.292  1.00 61.93  ? 20  HIS B N   1 
ATOM 3058  C CA  . HIS B 1 20  ? -35.512 -24.669 43.962  1.00 62.70  ? 20  HIS B CA  1 
ATOM 3059  C C   . HIS B 1 20  ? -36.556 -23.824 43.250  1.00 58.41  ? 20  HIS B C   1 
ATOM 3060  O O   . HIS B 1 20  ? -36.231 -23.199 42.233  1.00 54.28  ? 20  HIS B O   1 
ATOM 3061  C CB  . HIS B 1 20  ? -35.169 -25.889 43.093  1.00 56.61  ? 20  HIS B CB  1 
ATOM 3062  C CG  . HIS B 1 20  ? -33.970 -26.650 43.566  1.00 54.86  ? 20  HIS B CG  1 
ATOM 3063  N ND1 . HIS B 1 20  ? -33.977 -27.411 44.717  1.00 57.19  ? 20  HIS B ND1 1 
ATOM 3064  C CD2 . HIS B 1 20  ? -32.723 -26.761 43.050  1.00 44.26  ? 20  HIS B CD2 1 
ATOM 3065  C CE1 . HIS B 1 20  ? -32.787 -27.962 44.884  1.00 65.47  ? 20  HIS B CE1 1 
ATOM 3066  N NE2 . HIS B 1 20  ? -32.009 -27.584 43.886  1.00 56.50  ? 20  HIS B NE2 1 
ATOM 3067  N N   . ILE B 1 21  ? -37.793 -23.786 43.749  1.00 55.00  ? 21  ILE B N   1 
ATOM 3068  C CA  . ILE B 1 21  ? -38.814 -22.956 43.124  1.00 51.20  ? 21  ILE B CA  1 
ATOM 3069  C C   . ILE B 1 21  ? -38.555 -21.482 43.411  1.00 53.50  ? 21  ILE B C   1 
ATOM 3070  O O   . ILE B 1 21  ? -38.745 -20.622 42.544  1.00 59.24  ? 21  ILE B O   1 
ATOM 3071  C CB  . ILE B 1 21  ? -40.214 -23.389 43.597  1.00 53.34  ? 21  ILE B CB  1 
ATOM 3072  C CG1 . ILE B 1 21  ? -40.514 -24.812 43.130  1.00 55.93  ? 21  ILE B CG1 1 
ATOM 3073  C CG2 . ILE B 1 21  ? -41.273 -22.437 43.072  1.00 46.16  ? 21  ILE B CG2 1 
ATOM 3074  C CD1 . ILE B 1 21  ? -40.729 -24.923 41.637  1.00 66.48  ? 21  ILE B CD1 1 
ATOM 3075  N N   . SER B 1 22  ? -38.110 -21.163 44.632  1.00 50.18  ? 22  SER B N   1 
ATOM 3076  C CA  . SER B 1 22  ? -37.866 -19.763 44.976  1.00 55.15  ? 22  SER B CA  1 
ATOM 3077  C C   . SER B 1 22  ? -36.723 -19.155 44.171  1.00 53.61  ? 22  SER B C   1 
ATOM 3078  O O   . SER B 1 22  ? -36.905 -18.054 43.624  1.00 50.83  ? 22  SER B O   1 
ATOM 3079  C CB  . SER B 1 22  ? -37.636 -19.626 46.484  1.00 51.19  ? 22  SER B CB  1 
ATOM 3080  O OG  . SER B 1 22  ? -38.768 -20.062 47.211  1.00 63.07  ? 22  SER B OG  1 
ATOM 3081  N N   . PRO B 1 23  ? -35.540 -19.777 44.064  1.00 52.92  ? 23  PRO B N   1 
ATOM 3082  C CA  . PRO B 1 23  ? -34.484 -19.149 43.250  1.00 52.29  ? 23  PRO B CA  1 
ATOM 3083  C C   . PRO B 1 23  ? -34.876 -18.987 41.790  1.00 48.97  ? 23  PRO B C   1 
ATOM 3084  O O   . PRO B 1 23  ? -34.588 -17.944 41.189  1.00 44.92  ? 23  PRO B O   1 
ATOM 3085  C CB  . PRO B 1 23  ? -33.295 -20.103 43.420  1.00 55.85  ? 23  PRO B CB  1 
ATOM 3086  C CG  . PRO B 1 23  ? -33.565 -20.828 44.689  1.00 53.61  ? 23  PRO B CG  1 
ATOM 3087  C CD  . PRO B 1 23  ? -35.049 -21.000 44.724  1.00 52.84  ? 23  PRO B CD  1 
ATOM 3088  N N   . PHE B 1 24  ? -35.539 -19.989 41.204  1.00 49.43  ? 24  PHE B N   1 
ATOM 3089  C CA  . PHE B 1 24  ? -35.999 -19.863 39.826  1.00 48.55  ? 24  PHE B CA  1 
ATOM 3090  C C   . PHE B 1 24  ? -37.015 -18.738 39.681  1.00 45.29  ? 24  PHE B C   1 
ATOM 3091  O O   . PHE B 1 24  ? -36.971 -17.976 38.708  1.00 42.74  ? 24  PHE B O   1 
ATOM 3092  C CB  . PHE B 1 24  ? -36.595 -21.188 39.350  1.00 44.92  ? 24  PHE B CB  1 
ATOM 3093  C CG  . PHE B 1 24  ? -35.586 -22.121 38.737  1.00 44.56  ? 24  PHE B CG  1 
ATOM 3094  C CD1 . PHE B 1 24  ? -34.725 -22.856 39.534  1.00 41.69  ? 24  PHE B CD1 1 
ATOM 3095  C CD2 . PHE B 1 24  ? -35.507 -22.263 37.362  1.00 39.43  ? 24  PHE B CD2 1 
ATOM 3096  C CE1 . PHE B 1 24  ? -33.801 -23.715 38.970  1.00 37.00  ? 24  PHE B CE1 1 
ATOM 3097  C CE2 . PHE B 1 24  ? -34.583 -23.118 36.792  1.00 41.76  ? 24  PHE B CE2 1 
ATOM 3098  C CZ  . PHE B 1 24  ? -33.731 -23.847 37.598  1.00 36.76  ? 24  PHE B CZ  1 
ATOM 3099  N N   . PHE B 1 25  ? -37.932 -18.602 40.645  1.00 47.62  ? 25  PHE B N   1 
ATOM 3100  C CA  . PHE B 1 25  ? -38.939 -17.548 40.561  1.00 51.27  ? 25  PHE B CA  1 
ATOM 3101  C C   . PHE B 1 25  ? -38.317 -16.168 40.711  1.00 50.73  ? 25  PHE B C   1 
ATOM 3102  O O   . PHE B 1 25  ? -38.718 -15.218 40.024  1.00 52.78  ? 25  PHE B O   1 
ATOM 3103  C CB  . PHE B 1 25  ? -40.018 -17.767 41.620  1.00 54.75  ? 25  PHE B CB  1 
ATOM 3104  C CG  . PHE B 1 25  ? -41.014 -16.648 41.711  1.00 57.00  ? 25  PHE B CG  1 
ATOM 3105  C CD1 . PHE B 1 25  ? -41.783 -16.297 40.612  1.00 59.40  ? 25  PHE B CD1 1 
ATOM 3106  C CD2 . PHE B 1 25  ? -41.189 -15.950 42.894  1.00 51.80  ? 25  PHE B CD2 1 
ATOM 3107  C CE1 . PHE B 1 25  ? -42.701 -15.268 40.690  1.00 57.38  ? 25  PHE B CE1 1 
ATOM 3108  C CE2 . PHE B 1 25  ? -42.113 -14.923 42.981  1.00 57.30  ? 25  PHE B CE2 1 
ATOM 3109  C CZ  . PHE B 1 25  ? -42.869 -14.582 41.875  1.00 62.22  ? 25  PHE B CZ  1 
ATOM 3110  N N   . GLU B 1 26  ? -37.333 -16.032 41.601  1.00 54.82  ? 26  GLU B N   1 
ATOM 3111  C CA  . GLU B 1 26  ? -36.665 -14.746 41.760  1.00 52.73  ? 26  GLU B CA  1 
ATOM 3112  C C   . GLU B 1 26  ? -35.839 -14.400 40.528  1.00 45.33  ? 26  GLU B C   1 
ATOM 3113  O O   . GLU B 1 26  ? -35.811 -13.240 40.100  1.00 41.89  ? 26  GLU B O   1 
ATOM 3114  C CB  . GLU B 1 26  ? -35.793 -14.756 43.017  1.00 50.58  ? 26  GLU B CB  1 
ATOM 3115  C CG  . GLU B 1 26  ? -36.591 -14.781 44.316  1.00 52.17  ? 26  GLU B CG  1 
ATOM 3116  C CD  . GLU B 1 26  ? -37.441 -13.537 44.507  1.00 60.12  ? 26  GLU B CD  1 
ATOM 3117  O OE1 . GLU B 1 26  ? -37.077 -12.473 43.960  1.00 57.99  ? 26  GLU B OE1 1 
ATOM 3118  O OE2 . GLU B 1 26  ? -38.476 -13.619 45.202  1.00 71.74  ? 26  GLU B OE2 1 
ATOM 3119  N N   . LEU B 1 27  ? -35.169 -15.394 39.936  1.00 50.72  ? 27  LEU B N   1 
ATOM 3120  C CA  . LEU B 1 27  ? -34.482 -15.160 38.670  1.00 43.51  ? 27  LEU B CA  1 
ATOM 3121  C C   . LEU B 1 27  ? -35.466 -14.761 37.583  1.00 40.32  ? 27  LEU B C   1 
ATOM 3122  O O   . LEU B 1 27  ? -35.151 -13.928 36.726  1.00 47.43  ? 27  LEU B O   1 
ATOM 3123  C CB  . LEU B 1 27  ? -33.699 -16.403 38.253  1.00 33.51  ? 27  LEU B CB  1 
ATOM 3124  C CG  . LEU B 1 27  ? -32.894 -16.276 36.958  1.00 35.57  ? 27  LEU B CG  1 
ATOM 3125  C CD1 . LEU B 1 27  ? -31.879 -15.147 37.060  1.00 40.60  ? 27  LEU B CD1 1 
ATOM 3126  C CD2 . LEU B 1 27  ? -32.209 -17.589 36.631  1.00 36.40  ? 27  LEU B CD2 1 
ATOM 3127  N N   . ALA B 1 28  ? -36.665 -15.346 37.597  1.00 41.26  ? 28  ALA B N   1 
ATOM 3128  C CA  . ALA B 1 28  ? -37.697 -14.955 36.643  1.00 41.95  ? 28  ALA B CA  1 
ATOM 3129  C C   . ALA B 1 28  ? -38.077 -13.491 36.818  1.00 42.28  ? 28  ALA B C   1 
ATOM 3130  O O   . ALA B 1 28  ? -38.159 -12.735 35.844  1.00 53.26  ? 28  ALA B O   1 
ATOM 3131  C CB  . ALA B 1 28  ? -38.925 -15.853 36.803  1.00 40.79  ? 28  ALA B CB  1 
ATOM 3132  N N   . LYS B 1 29  ? -38.316 -13.076 38.063  1.00 43.30  ? 29  LYS B N   1 
ATOM 3133  C CA  . LYS B 1 29  ? -38.643 -11.677 38.327  1.00 45.44  ? 29  LYS B CA  1 
ATOM 3134  C C   . LYS B 1 29  ? -37.505 -10.751 37.912  1.00 48.14  ? 29  LYS B C   1 
ATOM 3135  O O   . LYS B 1 29  ? -37.744 -9.631  37.450  1.00 59.19  ? 29  LYS B O   1 
ATOM 3136  C CB  . LYS B 1 29  ? -38.965 -11.480 39.807  1.00 43.59  ? 29  LYS B CB  1 
ATOM 3137  C CG  . LYS B 1 29  ? -40.116 -12.326 40.309  1.00 42.77  ? 29  LYS B CG  1 
ATOM 3138  C CD  . LYS B 1 29  ? -40.223 -12.243 41.820  1.00 56.30  ? 29  LYS B CD  1 
ATOM 3139  C CE  . LYS B 1 29  ? -40.582 -10.838 42.277  1.00 69.71  ? 29  LYS B CE  1 
ATOM 3140  N NZ  . LYS B 1 29  ? -40.776 -10.775 43.751  1.00 74.53  ? 29  LYS B NZ  1 
ATOM 3141  N N   . GLN B 1 30  ? -36.258 -11.202 38.072  1.00 51.52  ? 30  GLN B N   1 
ATOM 3142  C CA  . GLN B 1 30  ? -35.125 -10.353 37.717  1.00 50.53  ? 30  GLN B CA  1 
ATOM 3143  C C   . GLN B 1 30  ? -34.955 -10.249 36.205  1.00 56.31  ? 30  GLN B C   1 
ATOM 3144  O O   . GLN B 1 30  ? -34.602 -9.182  35.686  1.00 53.27  ? 30  GLN B O   1 
ATOM 3145  C CB  . GLN B 1 30  ? -33.848 -10.879 38.366  1.00 44.03  ? 30  GLN B CB  1 
ATOM 3146  C CG  . GLN B 1 30  ? -33.822 -10.717 39.873  1.00 52.57  ? 30  GLN B CG  1 
ATOM 3147  C CD  . GLN B 1 30  ? -34.004 -9.274  40.305  1.00 58.33  ? 30  GLN B CD  1 
ATOM 3148  O OE1 . GLN B 1 30  ? -33.410 -8.360  39.729  1.00 50.60  ? 30  GLN B OE1 1 
ATOM 3149  N NE2 . GLN B 1 30  ? -34.837 -9.060  41.320  1.00 55.19  ? 30  GLN B NE2 1 
ATOM 3150  N N   . LEU B 1 31  ? -35.192 -11.338 35.479  1.00 51.28  ? 31  LEU B N   1 
ATOM 3151  C CA  . LEU B 1 31  ? -35.047 -11.288 34.032  1.00 51.09  ? 31  LEU B CA  1 
ATOM 3152  C C   . LEU B 1 31  ? -36.266 -10.695 33.344  1.00 58.12  ? 31  LEU B C   1 
ATOM 3153  O O   . LEU B 1 31  ? -36.179 -10.326 32.168  1.00 55.82  ? 31  LEU B O   1 
ATOM 3154  C CB  . LEU B 1 31  ? -34.771 -12.685 33.473  1.00 52.56  ? 31  LEU B CB  1 
ATOM 3155  C CG  . LEU B 1 31  ? -33.600 -13.489 34.045  1.00 51.84  ? 31  LEU B CG  1 
ATOM 3156  C CD1 . LEU B 1 31  ? -33.350 -14.733 33.215  1.00 48.12  ? 31  LEU B CD1 1 
ATOM 3157  C CD2 . LEU B 1 31  ? -32.342 -12.651 34.142  1.00 62.58  ? 31  LEU B CD2 1 
ATOM 3158  N N   . ALA B 1 32  ? -37.400 -10.592 34.044  1.00 59.77  ? 32  ALA B N   1 
ATOM 3159  C CA  . ALA B 1 32  ? -38.592 -9.992  33.458  1.00 54.43  ? 32  ALA B CA  1 
ATOM 3160  C C   . ALA B 1 32  ? -38.582 -8.471  33.527  1.00 56.56  ? 32  ALA B C   1 
ATOM 3161  O O   . ALA B 1 32  ? -39.279 -7.825  32.736  1.00 59.16  ? 32  ALA B O   1 
ATOM 3162  C CB  . ALA B 1 32  ? -39.845 -10.529 34.151  1.00 46.56  ? 32  ALA B CB  1 
ATOM 3163  N N   . LYS B 1 33  ? -37.813 -7.887  34.442  1.00 60.12  ? 33  LYS B N   1 
ATOM 3164  C CA  . LYS B 1 33  ? -37.747 -6.440  34.577  1.00 58.55  ? 33  LYS B CA  1 
ATOM 3165  C C   . LYS B 1 33  ? -36.674 -5.804  33.706  1.00 58.77  ? 33  LYS B C   1 
ATOM 3166  O O   . LYS B 1 33  ? -36.593 -4.573  33.652  1.00 66.53  ? 33  LYS B O   1 
ATOM 3167  C CB  . LYS B 1 33  ? -37.512 -6.061  36.041  1.00 54.71  ? 33  LYS B CB  1 
ATOM 3168  C CG  . LYS B 1 33  ? -36.312 -6.745  36.660  1.00 53.32  ? 33  LYS B CG  1 
ATOM 3169  C CD  . LYS B 1 33  ? -36.277 -6.560  38.163  1.00 61.80  ? 33  LYS B CD  1 
ATOM 3170  C CE  . LYS B 1 33  ? -35.985 -5.121  38.538  1.00 63.69  ? 33  LYS B CE  1 
ATOM 3171  N NZ  . LYS B 1 33  ? -35.835 -4.970  40.012  1.00 78.10  ? 33  LYS B NZ  1 
ATOM 3172  N N   . ARG B 1 34  ? -35.874 -6.671  33.072  1.00 58.02  ? 34  ARG B N   1 
ATOM 3173  C CA  . ARG B 1 34  ? -34.777 -6.222  32.181  1.00 60.27  ? 34  ARG B CA  1 
ATOM 3174  C C   . ARG B 1 34  ? -34.940 -6.892  30.820  1.00 78.62  ? 34  ARG B C   1 
ATOM 3175  O O   . ARG B 1 34  ? -35.191 -8.099  30.789  1.00 77.83  ? 34  ARG B O   1 
ATOM 3176  C CB  . ARG B 1 34  ? -33.407 -6.562  32.761  1.00 48.60  ? 34  ARG B CB  1 
ATOM 3177  C CG  . ARG B 1 34  ? -33.237 -7.984  33.266  1.00 55.47  ? 34  ARG B CG  1 
ATOM 3178  C CD  . ARG B 1 34  ? -31.934 -8.024  34.032  1.00 56.41  ? 34  ARG B CD  1 
ATOM 3179  N NE  . ARG B 1 34  ? -31.751 -6.809  34.805  1.00 57.90  ? 34  ARG B NE  1 
ATOM 3180  C CZ  . ARG B 1 34  ? -31.931 -6.709  36.114  1.00 50.76  ? 34  ARG B CZ  1 
ATOM 3181  N NH1 . ARG B 1 34  ? -32.285 -7.765  36.822  1.00 59.07  ? 34  ARG B NH1 1 
ATOM 3182  N NH2 . ARG B 1 34  ? -31.745 -5.549  36.711  1.00 61.80  ? 34  ARG B NH2 1 
ATOM 3183  N N   . ASN B 1 35  ? -34.923 -6.105  29.748  1.00 84.91  ? 35  ASN B N   1 
ATOM 3184  C CA  . ASN B 1 35  ? -35.044 -6.631  28.360  1.00 84.28  ? 35  ASN B CA  1 
ATOM 3185  C C   . ASN B 1 35  ? -36.460 -7.147  28.161  1.00 89.33  ? 35  ASN B C   1 
ATOM 3186  O O   . ASN B 1 35  ? -36.707 -7.769  27.120  1.00 89.34  ? 35  ASN B O   1 
ATOM 3187  C CB  . ASN B 1 35  ? -33.912 -7.572  27.952  1.00 81.60  ? 35  ASN B CB  1 
ATOM 3188  C CG  . ASN B 1 35  ? -32.828 -6.863  27.166  1.00 93.56  ? 35  ASN B CG  1 
ATOM 3189  O OD1 . ASN B 1 35  ? -32.765 -5.635  27.158  1.00 90.21  ? 35  ASN B OD1 1 
ATOM 3190  N ND2 . ASN B 1 35  ? -31.974 -7.622  26.502  1.00 94.21  ? 35  ASN B ND2 1 
ATOM 3191  N N   . CYS B 1 36  ? -37.329 -6.935  29.147  1.00 84.14  ? 36  CYS B N   1 
ATOM 3192  C CA  . CYS B 1 36  ? -38.756 -7.288  28.979  1.00 85.53  ? 36  CYS B CA  1 
ATOM 3193  C C   . CYS B 1 36  ? -38.812 -8.719  28.470  1.00 82.36  ? 36  CYS B C   1 
ATOM 3194  O O   . CYS B 1 36  ? -39.621 -8.998  27.570  1.00 89.94  ? 36  CYS B O   1 
ATOM 3195  C CB  . CYS B 1 36  ? -39.445 -6.323  28.023  1.00 88.42  ? 36  CYS B CB  1 
ATOM 3196  S SG  . CYS B 1 36  ? -39.363 -4.600  28.573  1.00 119.46 ? 36  CYS B SG  1 
ATOM 3197  N N   . ASN B 1 37  ? -37.894 -9.548  28.950  1.00 68.73  ? 37  ASN B N   1 
ATOM 3198  C CA  . ASN B 1 37  ? -37.842 -10.958 28.507  1.00 57.44  ? 37  ASN B CA  1 
ATOM 3199  C C   . ASN B 1 37  ? -39.206 -11.583 28.750  1.00 56.98  ? 37  ASN B C   1 
ATOM 3200  O O   . ASN B 1 37  ? -39.683 -11.511 29.888  1.00 60.81  ? 37  ASN B O   1 
ATOM 3201  C CB  . ASN B 1 37  ? -36.708 -11.721 29.194  1.00 59.10  ? 37  ASN B CB  1 
ATOM 3202  C CG  . ASN B 1 37  ? -35.334 -11.165 28.899  1.00 59.38  ? 37  ASN B CG  1 
ATOM 3203  O OD1 . ASN B 1 37  ? -35.127 -10.528 27.871  1.00 78.56  ? 37  ASN B OD1 1 
ATOM 3204  N ND2 . ASN B 1 37  ? -34.387 -11.415 29.786  1.00 55.73  ? 37  ASN B ND2 1 
ATOM 3205  N N   . VAL B 1 38  ? -39.838 -12.113 27.699  1.00 54.38  ? 38  VAL B N   1 
ATOM 3206  C CA  . VAL B 1 38  ? -41.131 -12.840 27.873  1.00 63.71  ? 38  VAL B CA  1 
ATOM 3207  C C   . VAL B 1 38  ? -40.807 -14.040 28.758  1.00 64.38  ? 38  VAL B C   1 
ATOM 3208  O O   . VAL B 1 38  ? -39.906 -14.815 28.385  1.00 57.80  ? 38  VAL B O   1 
ATOM 3209  C CB  . VAL B 1 38  ? -41.717 -13.278 26.519  1.00 60.62  ? 38  VAL B CB  1 
ATOM 3210  C CG1 . VAL B 1 38  ? -43.046 -14.001 26.681  1.00 51.89  ? 38  VAL B CG1 1 
ATOM 3211  C CG2 . VAL B 1 38  ? -41.857 -12.104 25.562  1.00 65.11  ? 38  VAL B CG2 1 
ATOM 3212  N N   . PHE B 1 39  ? -41.530 -14.231 29.854  1.00 62.04  ? 39  PHE B N   1 
ATOM 3213  C CA  . PHE B 1 39  ? -41.094 -15.291 30.786  1.00 57.61  ? 39  PHE B CA  1 
ATOM 3214  C C   . PHE B 1 39  ? -42.126 -16.387 30.964  1.00 53.19  ? 39  PHE B C   1 
ATOM 3215  O O   . PHE B 1 39  ? -43.253 -16.068 31.278  1.00 54.98  ? 39  PHE B O   1 
ATOM 3216  C CB  . PHE B 1 39  ? -40.665 -14.660 32.101  1.00 63.24  ? 39  PHE B CB  1 
ATOM 3217  C CG  . PHE B 1 39  ? -39.473 -13.791 31.870  1.00 69.33  ? 39  PHE B CG  1 
ATOM 3218  C CD1 . PHE B 1 39  ? -38.211 -14.346 31.833  1.00 64.63  ? 39  PHE B CD1 1 
ATOM 3219  C CD2 . PHE B 1 39  ? -39.612 -12.420 31.824  1.00 71.51  ? 39  PHE B CD2 1 
ATOM 3220  C CE1 . PHE B 1 39  ? -37.103 -13.537 31.684  1.00 65.00  ? 39  PHE B CE1 1 
ATOM 3221  C CE2 . PHE B 1 39  ? -38.503 -11.618 31.656  1.00 67.71  ? 39  PHE B CE2 1 
ATOM 3222  C CZ  . PHE B 1 39  ? -37.253 -12.176 31.591  1.00 66.07  ? 39  PHE B CZ  1 
ATOM 3223  N N   . LEU B 1 40  ? -41.698 -17.635 30.781  1.00 41.87  ? 40  LEU B N   1 
ATOM 3224  C CA  . LEU B 1 40  ? -42.607 -18.797 30.949  1.00 43.08  ? 40  LEU B CA  1 
ATOM 3225  C C   . LEU B 1 40  ? -41.986 -19.706 32.014  1.00 39.94  ? 40  LEU B C   1 
ATOM 3226  O O   . LEU B 1 40  ? -40.777 -19.961 31.919  1.00 44.42  ? 40  LEU B O   1 
ATOM 3227  C CB  . LEU B 1 40  ? -42.703 -19.521 29.603  1.00 51.13  ? 40  LEU B CB  1 
ATOM 3228  C CG  . LEU B 1 40  ? -42.891 -18.617 28.386  1.00 56.46  ? 40  LEU B CG  1 
ATOM 3229  C CD1 . LEU B 1 40  ? -42.309 -19.253 27.132  1.00 53.34  ? 40  LEU B CD1 1 
ATOM 3230  C CD2 . LEU B 1 40  ? -44.357 -18.263 28.185  1.00 52.92  ? 40  LEU B CD2 1 
ATOM 3231  N N   . CYS B 1 41  ? -42.663 -20.003 33.128  1.00 45.88  ? 41  CYS B N   1 
ATOM 3232  C CA  . CYS B 1 41  ? -42.085 -20.820 34.250  1.00 43.44  ? 41  CYS B CA  1 
ATOM 3233  C C   . CYS B 1 41  ? -42.915 -22.090 34.409  1.00 50.81  ? 41  CYS B C   1 
ATOM 3234  O O   . CYS B 1 41  ? -44.113 -21.952 34.599  1.00 50.43  ? 41  CYS B O   1 
ATOM 3235  C CB  . CYS B 1 41  ? -42.072 -20.052 35.562  1.00 47.05  ? 41  CYS B CB  1 
ATOM 3236  S SG  . CYS B 1 41  ? -41.124 -20.826 36.896  1.00 62.50  ? 41  CYS B SG  1 
ATOM 3237  N N   . SER B 1 42  ? -42.325 -23.255 34.118  1.00 49.13  ? 42  SER B N   1 
ATOM 3238  C CA  . SER B 1 42  ? -43.098 -24.526 34.109  1.00 52.55  ? 42  SER B CA  1 
ATOM 3239  C C   . SER B 1 42  ? -43.093 -25.171 35.492  1.00 54.85  ? 42  SER B C   1 
ATOM 3240  O O   . SER B 1 42  ? -42.050 -25.737 35.881  1.00 56.53  ? 42  SER B O   1 
ATOM 3241  C CB  . SER B 1 42  ? -42.579 -25.470 33.059  1.00 48.42  ? 42  SER B CB  1 
ATOM 3242  O OG  . SER B 1 42  ? -43.412 -26.615 32.955  1.00 52.21  ? 42  SER B OG  1 
ATOM 3243  N N   . THR B 1 43  ? -44.223 -25.091 36.195  1.00 59.49  ? 43  THR B N   1 
ATOM 3244  C CA  . THR B 1 43  ? -44.326 -25.668 37.557  1.00 60.06  ? 43  THR B CA  1 
ATOM 3245  C C   . THR B 1 43  ? -45.662 -26.400 37.680  1.00 64.70  ? 43  THR B C   1 
ATOM 3246  O O   . THR B 1 43  ? -46.608 -26.008 36.972  1.00 61.80  ? 43  THR B O   1 
ATOM 3247  C CB  . THR B 1 43  ? -44.236 -24.550 38.603  1.00 75.56  ? 43  THR B CB  1 
ATOM 3248  O OG1 . THR B 1 43  ? -44.978 -23.449 38.077  1.00 67.59  ? 43  THR B OG1 1 
ATOM 3249  C CG2 . THR B 1 43  ? -42.818 -24.096 38.868  1.00 79.01  ? 43  THR B CG2 1 
ATOM 3250  N N   . PRO B 1 44  ? -45.795 -27.517 38.449  1.00 64.58  ? 44  PRO B N   1 
ATOM 3251  C CA  . PRO B 1 44  ? -47.105 -28.140 38.707  1.00 59.02  ? 44  PRO B CA  1 
ATOM 3252  C C   . PRO B 1 44  ? -48.004 -27.113 39.406  1.00 60.55  ? 44  PRO B C   1 
ATOM 3253  O O   . PRO B 1 44  ? -47.466 -26.307 40.124  1.00 60.80  ? 44  PRO B O   1 
ATOM 3254  C CB  . PRO B 1 44  ? -46.800 -29.355 39.581  1.00 59.51  ? 44  PRO B CB  1 
ATOM 3255  C CG  . PRO B 1 44  ? -45.398 -29.711 39.201  1.00 67.40  ? 44  PRO B CG  1 
ATOM 3256  C CD  . PRO B 1 44  ? -44.734 -28.361 39.032  1.00 78.07  ? 44  PRO B CD  1 
ATOM 3257  N N   . ILE B 1 45  ? -49.326 -27.168 39.221  1.00 60.29  ? 45  ILE B N   1 
ATOM 3258  C CA  . ILE B 1 45  ? -50.257 -26.108 39.709  1.00 62.51  ? 45  ILE B CA  1 
ATOM 3259  C C   . ILE B 1 45  ? -50.081 -25.927 41.224  1.00 57.55  ? 45  ILE B C   1 
ATOM 3260  O O   . ILE B 1 45  ? -50.077 -24.767 41.675  1.00 54.90  ? 45  ILE B O   1 
ATOM 3261  C CB  . ILE B 1 45  ? -51.712 -26.425 39.300  1.00 63.44  ? 45  ILE B CB  1 
ATOM 3262  C CG1 . ILE B 1 45  ? -52.703 -25.377 39.816  1.00 65.89  ? 45  ILE B CG1 1 
ATOM 3263  C CG2 . ILE B 1 45  ? -52.109 -27.836 39.713  1.00 75.63  ? 45  ILE B CG2 1 
ATOM 3264  C CD1 . ILE B 1 45  ? -52.525 -24.009 39.199  1.00 48.79  ? 45  ILE B CD1 1 
ATOM 3265  N N   . ASN B 1 46  ? -49.899 -27.021 41.970  1.00 49.46  ? 46  ASN B N   1 
ATOM 3266  C CA  . ASN B 1 46  ? -49.689 -26.925 43.438  1.00 57.27  ? 46  ASN B CA  1 
ATOM 3267  C C   . ASN B 1 46  ? -48.397 -26.146 43.730  1.00 56.61  ? 46  ASN B C   1 
ATOM 3268  O O   . ASN B 1 46  ? -48.412 -25.305 44.645  1.00 59.96  ? 46  ASN B O   1 
ATOM 3269  C CB  . ASN B 1 46  ? -49.648 -28.310 44.088  1.00 61.30  ? 46  ASN B CB  1 
ATOM 3270  C CG  . ASN B 1 46  ? -49.638 -28.262 45.601  1.00 59.15  ? 46  ASN B CG  1 
ATOM 3271  O OD1 . ASN B 1 46  ? -50.193 -27.345 46.203  1.00 60.56  ? 46  ASN B OD1 1 
ATOM 3272  N ND2 . ASN B 1 46  ? -49.021 -29.251 46.225  1.00 60.23  ? 46  ASN B ND2 1 
ATOM 3273  N N   . LEU B 1 47  ? -47.320 -26.429 42.994  1.00 55.12  ? 47  LEU B N   1 
ATOM 3274  C CA  . LEU B 1 47  ? -46.034 -25.701 43.193  1.00 50.43  ? 47  LEU B CA  1 
ATOM 3275  C C   . LEU B 1 47  ? -46.160 -24.227 42.786  1.00 45.93  ? 47  LEU B C   1 
ATOM 3276  O O   . LEU B 1 47  ? -45.582 -23.380 43.482  1.00 51.43  ? 47  LEU B O   1 
ATOM 3277  C CB  . LEU B 1 47  ? -44.905 -26.411 42.440  1.00 57.82  ? 47  LEU B CB  1 
ATOM 3278  C CG  . LEU B 1 47  ? -43.965 -27.235 43.320  1.00 56.51  ? 47  LEU B CG  1 
ATOM 3279  C CD1 . LEU B 1 47  ? -44.722 -28.321 44.066  1.00 59.21  ? 47  LEU B CD1 1 
ATOM 3280  C CD2 . LEU B 1 47  ? -42.847 -27.841 42.493  1.00 66.85  ? 47  LEU B CD2 1 
ATOM 3281  N N   . SER B 1 48  ? -46.864 -23.938 41.687  1.00 51.37  ? 48  SER B N   1 
ATOM 3282  C CA  . SER B 1 48  ? -46.981 -22.540 41.194  1.00 58.13  ? 48  SER B CA  1 
ATOM 3283  C C   . SER B 1 48  ? -47.903 -21.751 42.125  1.00 61.82  ? 48  SER B C   1 
ATOM 3284  O O   . SER B 1 48  ? -47.719 -20.527 42.243  1.00 62.24  ? 48  SER B O   1 
ATOM 3285  C CB  . SER B 1 48  ? -47.498 -22.516 39.779  1.00 57.07  ? 48  SER B CB  1 
ATOM 3286  O OG  . SER B 1 48  ? -48.824 -23.015 39.716  1.00 68.87  ? 48  SER B OG  1 
ATOM 3287  N N   . SER B 1 49  ? -48.854 -22.434 42.762  1.00 64.78  ? 49  SER B N   1 
ATOM 3288  C CA  . SER B 1 49  ? -49.839 -21.774 43.664  1.00 60.77  ? 49  SER B CA  1 
ATOM 3289  C C   . SER B 1 49  ? -49.160 -20.895 44.704  1.00 56.36  ? 49  SER B C   1 
ATOM 3290  O O   . SER B 1 49  ? -49.689 -19.817 44.985  1.00 59.50  ? 49  SER B O   1 
ATOM 3291  C CB  . SER B 1 49  ? -50.662 -22.805 44.364  1.00 56.11  ? 49  SER B CB  1 
ATOM 3292  O OG  . SER B 1 49  ? -49.955 -23.341 45.469  1.00 63.09  ? 49  SER B OG  1 
ATOM 3293  N N   . ILE B 1 50  ? -48.058 -21.365 45.284  1.00 57.44  ? 50  ILE B N   1 
ATOM 3294  C CA  . ILE B 1 50  ? -47.325 -20.612 46.347  1.00 67.53  ? 50  ILE B CA  1 
ATOM 3295  C C   . ILE B 1 50  ? -46.709 -19.339 45.779  1.00 71.87  ? 50  ILE B C   1 
ATOM 3296  O O   . ILE B 1 50  ? -46.628 -18.361 46.523  1.00 74.07  ? 50  ILE B O   1 
ATOM 3297  C CB  . ILE B 1 50  ? -46.234 -21.486 46.977  1.00 67.26  ? 50  ILE B CB  1 
ATOM 3298  C CG1 . ILE B 1 50  ? -45.799 -20.906 48.323  1.00 85.51  ? 50  ILE B CG1 1 
ATOM 3299  C CG2 . ILE B 1 50  ? -45.059 -21.671 46.034  1.00 56.06  ? 50  ILE B CG2 1 
ATOM 3300  C CD1 . ILE B 1 50  ? -46.955 -20.455 49.190  1.00 75.38  ? 50  ILE B CD1 1 
ATOM 3301  N N   . LYS B 1 51  ? -46.299 -19.361 44.519  1.00 67.76  ? 51  LYS B N   1 
ATOM 3302  C CA  . LYS B 1 51  ? -45.599 -18.203 43.931  1.00 64.73  ? 51  LYS B CA  1 
ATOM 3303  C C   . LYS B 1 51  ? -46.602 -17.173 43.434  1.00 66.82  ? 51  LYS B C   1 
ATOM 3304  O O   . LYS B 1 51  ? -46.162 -16.151 42.915  1.00 65.27  ? 51  LYS B O   1 
ATOM 3305  C CB  . LYS B 1 51  ? -44.696 -18.687 42.800  1.00 57.16  ? 51  LYS B CB  1 
ATOM 3306  C CG  . LYS B 1 51  ? -43.450 -19.401 43.296  1.00 62.33  ? 51  LYS B CG  1 
ATOM 3307  C CD  . LYS B 1 51  ? -42.831 -18.683 44.479  1.00 72.33  ? 51  LYS B CD  1 
ATOM 3308  C CE  . LYS B 1 51  ? -41.697 -19.440 45.134  1.00 68.71  ? 51  LYS B CE  1 
ATOM 3309  N NZ  . LYS B 1 51  ? -41.153 -18.695 46.291  1.00 50.77  ? 51  LYS B NZ  1 
ATOM 3310  N N   . ASP B 1 52  ? -47.896 -17.428 43.573  1.00 74.76  ? 52  ASP B N   1 
ATOM 3311  C CA  . ASP B 1 52  ? -48.861 -16.455 42.991  1.00 81.30  ? 52  ASP B CA  1 
ATOM 3312  C C   . ASP B 1 52  ? -49.068 -15.320 44.002  1.00 82.87  ? 52  ASP B C   1 
ATOM 3313  O O   . ASP B 1 52  ? -49.865 -15.481 44.945  1.00 86.10  ? 52  ASP B O   1 
ATOM 3314  C CB  . ASP B 1 52  ? -50.136 -17.133 42.488  1.00 71.91  ? 52  ASP B CB  1 
ATOM 3315  C CG  . ASP B 1 52  ? -50.920 -16.296 41.501  1.00 78.66  ? 52  ASP B CG  1 
ATOM 3316  O OD1 . ASP B 1 52  ? -51.293 -15.171 41.869  1.00 82.66  ? 52  ASP B OD1 1 
ATOM 3317  O OD2 . ASP B 1 52  ? -51.155 -16.782 40.386  1.00 81.65  ? 52  ASP B OD2 1 
ATOM 3318  N N   . LYS B 1 53  ? -48.336 -14.224 43.832  1.00 81.83  ? 53  LYS B N   1 
ATOM 3319  C CA  . LYS B 1 53  ? -48.424 -13.109 44.802  1.00 84.64  ? 53  LYS B CA  1 
ATOM 3320  C C   . LYS B 1 53  ? -47.903 -11.853 44.099  1.00 104.71 ? 53  LYS B C   1 
ATOM 3321  O O   . LYS B 1 53  ? -48.707 -10.939 43.902  1.00 112.83 ? 53  LYS B O   1 
ATOM 3322  C CB  . LYS B 1 53  ? -47.697 -13.522 46.082  1.00 88.12  ? 53  LYS B CB  1 
ATOM 3323  C CG  . LYS B 1 53  ? -46.311 -14.117 45.864  1.00 80.12  ? 53  LYS B CG  1 
ATOM 3324  C CD  . LYS B 1 53  ? -45.406 -14.006 47.066  1.00 69.36  ? 53  LYS B CD  1 
ATOM 3325  C CE  . LYS B 1 53  ? -43.974 -14.402 46.771  1.00 71.88  ? 53  LYS B CE  1 
ATOM 3326  N NZ  . LYS B 1 53  ? -43.835 -15.860 46.559  1.00 62.22  ? 53  LYS B NZ  1 
ATOM 3327  N N   . ASP B 1 54  ? -46.615 -11.801 43.727  1.00 108.53 ? 54  ASP B N   1 
ATOM 3328  C CA  . ASP B 1 54  ? -46.175 -10.639 42.910  1.00 108.92 ? 54  ASP B CA  1 
ATOM 3329  C C   . ASP B 1 54  ? -45.437 -11.174 41.681  1.00 101.55 ? 54  ASP B C   1 
ATOM 3330  O O   . ASP B 1 54  ? -44.199 -11.033 41.630  1.00 91.84  ? 54  ASP B O   1 
ATOM 3331  C CB  . ASP B 1 54  ? -45.298 -9.682  43.720  1.00 110.79 ? 54  ASP B CB  1 
ATOM 3332  C CG  . ASP B 1 54  ? -46.023 -9.008  44.871  1.00 130.55 ? 54  ASP B CG  1 
ATOM 3333  O OD1 . ASP B 1 54  ? -47.231 -9.271  45.038  1.00 132.07 ? 54  ASP B OD1 1 
ATOM 3334  O OD2 . ASP B 1 54  ? -45.373 -8.226  45.593  1.00 144.46 ? 54  ASP B OD2 1 
ATOM 3335  N N   . SER B 1 55  ? -46.169 -11.772 40.735  1.00 99.38  ? 55  SER B N   1 
ATOM 3336  C CA  . SER B 1 55  ? -45.516 -12.388 39.550  1.00 85.93  ? 55  SER B CA  1 
ATOM 3337  C C   . SER B 1 55  ? -46.198 -11.928 38.258  1.00 76.28  ? 55  SER B C   1 
ATOM 3338  O O   . SER B 1 55  ? -45.954 -12.560 37.214  1.00 75.65  ? 55  SER B O   1 
ATOM 3339  C CB  . SER B 1 55  ? -45.526 -13.890 39.660  1.00 84.12  ? 55  SER B CB  1 
ATOM 3340  O OG  . SER B 1 55  ? -46.855 -14.381 39.763  1.00 84.51  ? 55  SER B OG  1 
ATOM 3341  N N   . SER B 1 56  ? -47.015 -10.868 38.320  1.00 76.77  ? 56  SER B N   1 
ATOM 3342  C CA  . SER B 1 56  ? -47.625 -10.361 37.097  1.00 72.03  ? 56  SER B CA  1 
ATOM 3343  C C   . SER B 1 56  ? -46.615 -10.197 35.968  1.00 77.40  ? 56  SER B C   1 
ATOM 3344  O O   . SER B 1 56  ? -47.006 -10.197 34.796  1.00 74.36  ? 56  SER B O   1 
ATOM 3345  C CB  . SER B 1 56  ? -48.329 -9.034  37.380  1.00 80.50  ? 56  SER B CB  1 
ATOM 3346  O OG  . SER B 1 56  ? -49.398 -9.210  38.294  1.00 89.69  ? 56  SER B OG  1 
ATOM 3347  N N   . ALA B 1 57  ? -45.326 -10.074 36.292  1.00 78.85  ? 57  ALA B N   1 
ATOM 3348  C CA  . ALA B 1 57  ? -44.303 -9.940  35.262  1.00 72.61  ? 57  ALA B CA  1 
ATOM 3349  C C   . ALA B 1 57  ? -44.024 -11.266 34.567  1.00 71.26  ? 57  ALA B C   1 
ATOM 3350  O O   . ALA B 1 57  ? -43.876 -11.307 33.342  1.00 66.14  ? 57  ALA B O   1 
ATOM 3351  C CB  . ALA B 1 57  ? -43.017 -9.373  35.865  1.00 64.42  ? 57  ALA B CB  1 
ATOM 3352  N N   . SER B 1 58  ? -43.953 -12.353 35.327  1.00 70.70  ? 58  SER B N   1 
ATOM 3353  C CA  . SER B 1 58  ? -43.721 -13.674 34.771  1.00 60.12  ? 58  SER B CA  1 
ATOM 3354  C C   . SER B 1 58  ? -45.043 -14.334 34.391  1.00 52.37  ? 58  SER B C   1 
ATOM 3355  O O   . SER B 1 58  ? -46.120 -13.929 34.830  1.00 55.60  ? 58  SER B O   1 
ATOM 3356  C CB  . SER B 1 58  ? -42.971 -14.558 35.770  1.00 50.98  ? 58  SER B CB  1 
ATOM 3357  O OG  . SER B 1 58  ? -41.767 -13.943 36.205  1.00 53.72  ? 58  SER B OG  1 
ATOM 3358  N N   . ILE B 1 59  ? -44.943 -15.367 33.560  1.00 53.33  ? 59  ILE B N   1 
ATOM 3359  C CA  . ILE B 1 59  ? -46.088 -16.170 33.150  1.00 55.47  ? 59  ILE B CA  1 
ATOM 3360  C C   . ILE B 1 59  ? -45.855 -17.595 33.634  1.00 50.44  ? 59  ILE B C   1 
ATOM 3361  O O   . ILE B 1 59  ? -44.833 -18.209 33.304  1.00 53.89  ? 59  ILE B O   1 
ATOM 3362  C CB  . ILE B 1 59  ? -46.301 -16.131 31.628  1.00 46.46  ? 59  ILE B CB  1 
ATOM 3363  C CG1 . ILE B 1 59  ? -46.728 -14.727 31.182  1.00 56.02  ? 59  ILE B CG1 1 
ATOM 3364  C CG2 . ILE B 1 59  ? -47.331 -17.167 31.202  1.00 58.35  ? 59  ILE B CG2 1 
ATOM 3365  C CD1 . ILE B 1 59  ? -46.967 -14.600 29.692  1.00 65.10  ? 59  ILE B CD1 1 
ATOM 3366  N N   . LYS B 1 60  ? -46.783 -18.042 34.461  1.00 43.77  ? 60  LYS B N   1 
ATOM 3367  C CA  . LYS B 1 60  ? -46.632 -19.378 35.054  1.00 48.59  ? 60  LYS B CA  1 
ATOM 3368  C C   . LYS B 1 60  ? -47.396 -20.354 34.172  1.00 38.09  ? 60  LYS B C   1 
ATOM 3369  O O   . LYS B 1 60  ? -48.476 -20.010 33.708  1.00 41.00  ? 60  LYS B O   1 
ATOM 3370  C CB  . LYS B 1 60  ? -47.039 -19.296 36.526  1.00 52.44  ? 60  LYS B CB  1 
ATOM 3371  C CG  . LYS B 1 60  ? -46.347 -18.193 37.310  1.00 57.98  ? 60  LYS B CG  1 
ATOM 3372  C CD  . LYS B 1 60  ? -47.267 -17.538 38.303  1.00 73.67  ? 60  LYS B CD  1 
ATOM 3373  C CE  . LYS B 1 60  ? -47.852 -18.533 39.280  1.00 72.16  ? 60  LYS B CE  1 
ATOM 3374  N NZ  . LYS B 1 60  ? -46.791 -19.265 40.008  1.00 85.10  ? 60  LYS B NZ  1 
ATOM 3375  N N   . LEU B 1 61  ? -46.815 -21.518 33.949  1.00 40.24  ? 61  LEU B N   1 
ATOM 3376  C CA  . LEU B 1 61  ? -47.397 -22.509 33.025  1.00 47.22  ? 61  LEU B CA  1 
ATOM 3377  C C   . LEU B 1 61  ? -47.581 -23.808 33.798  1.00 49.21  ? 61  LEU B C   1 
ATOM 3378  O O   . LEU B 1 61  ? -46.670 -24.198 34.505  1.00 51.38  ? 61  LEU B O   1 
ATOM 3379  C CB  . LEU B 1 61  ? -46.403 -22.653 31.876  1.00 47.21  ? 61  LEU B CB  1 
ATOM 3380  C CG  . LEU B 1 61  ? -46.530 -23.916 31.045  1.00 48.62  ? 61  LEU B CG  1 
ATOM 3381  C CD1 . LEU B 1 61  ? -47.567 -23.733 29.952  1.00 66.96  ? 61  LEU B CD1 1 
ATOM 3382  C CD2 . LEU B 1 61  ? -45.181 -24.247 30.454  1.00 57.51  ? 61  LEU B CD2 1 
ATOM 3383  N N   . VAL B 1 62  ? -48.728 -24.443 33.660  1.00 40.19  ? 62  VAL B N   1 
ATOM 3384  C CA  . VAL B 1 62  ? -49.001 -25.635 34.497  1.00 39.88  ? 62  VAL B CA  1 
ATOM 3385  C C   . VAL B 1 62  ? -48.327 -26.872 33.923  1.00 42.75  ? 62  VAL B C   1 
ATOM 3386  O O   . VAL B 1 62  ? -47.796 -26.803 32.823  1.00 52.62  ? 62  VAL B O   1 
ATOM 3387  C CB  . VAL B 1 62  ? -50.515 -25.849 34.631  1.00 45.71  ? 62  VAL B CB  1 
ATOM 3388  C CG1 . VAL B 1 62  ? -51.192 -24.693 35.346  1.00 56.76  ? 62  VAL B CG1 1 
ATOM 3389  C CG2 . VAL B 1 62  ? -51.172 -26.102 33.286  1.00 70.61  ? 62  VAL B CG2 1 
ATOM 3390  N N   . GLU B 1 63  ? -48.423 -27.977 34.660  1.00 56.10  ? 63  GLU B N   1 
ATOM 3391  C CA  . GLU B 1 63  ? -47.777 -29.210 34.226  1.00 51.74  ? 63  GLU B CA  1 
ATOM 3392  C C   . GLU B 1 63  ? -48.356 -30.363 35.028  1.00 62.55  ? 63  GLU B C   1 
ATOM 3393  O O   . GLU B 1 63  ? -48.228 -30.391 36.255  1.00 61.00  ? 63  GLU B O   1 
ATOM 3394  C CB  . GLU B 1 63  ? -46.258 -29.144 34.398  1.00 44.91  ? 63  GLU B CB  1 
ATOM 3395  C CG  . GLU B 1 63  ? -45.553 -30.404 33.934  1.00 60.04  ? 63  GLU B CG  1 
ATOM 3396  C CD  . GLU B 1 63  ? -44.056 -30.221 33.781  1.00 65.86  ? 63  GLU B CD  1 
ATOM 3397  O OE1 . GLU B 1 63  ? -43.525 -29.201 34.266  1.00 54.29  ? 63  GLU B OE1 1 
ATOM 3398  O OE2 . GLU B 1 63  ? -43.413 -31.100 33.166  1.00 65.14  ? 63  GLU B OE2 1 
ATOM 3399  N N   . LEU B 1 64  ? -48.989 -31.306 34.335  1.00 71.16  ? 64  LEU B N   1 
ATOM 3400  C CA  . LEU B 1 64  ? -49.710 -32.403 34.963  1.00 77.75  ? 64  LEU B CA  1 
ATOM 3401  C C   . LEU B 1 64  ? -48.936 -33.704 34.794  1.00 75.86  ? 64  LEU B C   1 
ATOM 3402  O O   . LEU B 1 64  ? -48.434 -34.003 33.705  1.00 71.71  ? 64  LEU B O   1 
ATOM 3403  C CB  . LEU B 1 64  ? -51.111 -32.551 34.365  1.00 80.59  ? 64  LEU B CB  1 
ATOM 3404  C CG  . LEU B 1 64  ? -52.147 -31.460 34.659  1.00 73.87  ? 64  LEU B CG  1 
ATOM 3405  C CD1 . LEU B 1 64  ? -52.146 -31.088 36.138  1.00 80.45  ? 64  LEU B CD1 1 
ATOM 3406  C CD2 . LEU B 1 64  ? -51.963 -30.223 33.779  1.00 55.36  ? 64  LEU B CD2 1 
ATOM 3407  N N   . HIS B 1 65  ? -48.848 -34.475 35.872  1.00 74.39  ? 65  HIS B N   1 
ATOM 3408  C CA  . HIS B 1 65  ? -48.146 -35.752 35.846  1.00 78.34  ? 65  HIS B CA  1 
ATOM 3409  C C   . HIS B 1 65  ? -49.138 -36.914 35.858  1.00 76.71  ? 65  HIS B C   1 
ATOM 3410  O O   . HIS B 1 65  ? -48.929 -37.919 36.539  1.00 81.87  ? 65  HIS B O   1 
ATOM 3411  C CB  . HIS B 1 65  ? -47.184 -35.862 37.033  1.00 81.84  ? 65  HIS B CB  1 
ATOM 3412  C CG  . HIS B 1 65  ? -46.075 -34.857 37.006  1.00 72.27  ? 65  HIS B CG  1 
ATOM 3413  N ND1 . HIS B 1 65  ? -45.647 -34.248 35.847  1.00 76.36  ? 65  HIS B ND1 1 
ATOM 3414  C CD2 . HIS B 1 65  ? -45.306 -34.351 38.002  1.00 70.96  ? 65  HIS B CD2 1 
ATOM 3415  C CE1 . HIS B 1 65  ? -44.660 -33.413 36.126  1.00 69.80  ? 65  HIS B CE1 1 
ATOM 3416  N NE2 . HIS B 1 65  ? -44.435 -33.459 37.426  1.00 76.18  ? 65  HIS B NE2 1 
ATOM 3417  N N   . ARG B 1 91  ? -40.864 -42.850 43.235  1.00 105.38 ? 91  ARG B N   1 
ATOM 3418  C CA  . ARG B 1 91  ? -40.262 -42.426 41.945  1.00 109.11 ? 91  ARG B CA  1 
ATOM 3419  C C   . ARG B 1 91  ? -41.018 -41.211 41.413  1.00 113.43 ? 91  ARG B C   1 
ATOM 3420  O O   . ARG B 1 91  ? -42.160 -41.395 40.972  1.00 113.89 ? 91  ARG B O   1 
ATOM 3421  C CB  . ARG B 1 91  ? -40.341 -43.564 40.925  1.00 108.96 ? 91  ARG B CB  1 
ATOM 3422  C CG  . ARG B 1 91  ? -39.524 -44.794 41.305  1.00 113.32 ? 91  ARG B CG  1 
ATOM 3423  C CD  . ARG B 1 91  ? -38.178 -44.813 40.608  1.00 116.77 ? 91  ARG B CD  1 
ATOM 3424  N NE  . ARG B 1 91  ? -38.244 -44.174 39.302  1.00 130.56 ? 91  ARG B NE  1 
ATOM 3425  C CZ  . ARG B 1 91  ? -38.228 -44.822 38.145  1.00 141.71 ? 91  ARG B CZ  1 
ATOM 3426  N NH1 . ARG B 1 91  ? -38.143 -46.141 38.127  1.00 146.13 ? 91  ARG B NH1 1 
ATOM 3427  N NH2 . ARG B 1 91  ? -38.300 -44.150 37.011  1.00 133.38 ? 91  ARG B NH2 1 
ATOM 3428  N N   . ASN B 1 92  ? -40.406 -40.024 41.471  1.00 106.27 ? 92  ASN B N   1 
ATOM 3429  C CA  . ASN B 1 92  ? -41.061 -38.838 40.872  1.00 97.39  ? 92  ASN B CA  1 
ATOM 3430  C C   . ASN B 1 92  ? -41.411 -39.192 39.431  1.00 102.58 ? 92  ASN B C   1 
ATOM 3431  O O   . ASN B 1 92  ? -40.531 -39.663 38.701  1.00 103.07 ? 92  ASN B O   1 
ATOM 3432  C CB  . ASN B 1 92  ? -40.213 -37.571 40.974  1.00 91.96  ? 92  ASN B CB  1 
ATOM 3433  C CG  . ASN B 1 92  ? -38.880 -37.654 40.259  1.00 93.46  ? 92  ASN B CG  1 
ATOM 3434  O OD1 . ASN B 1 92  ? -38.464 -38.722 39.822  1.00 99.74  ? 92  ASN B OD1 1 
ATOM 3435  N ND2 . ASN B 1 92  ? -38.188 -36.530 40.165  1.00 84.42  ? 92  ASN B ND2 1 
ATOM 3436  N N   . ALA B 1 93  ? -42.672 -38.997 39.061  1.00 104.32 ? 93  ALA B N   1 
ATOM 3437  C CA  . ALA B 1 93  ? -43.083 -39.271 37.675  1.00 91.81  ? 93  ALA B CA  1 
ATOM 3438  C C   . ALA B 1 93  ? -42.463 -38.183 36.812  1.00 84.57  ? 93  ALA B C   1 
ATOM 3439  O O   . ALA B 1 93  ? -42.547 -38.272 35.585  1.00 84.01  ? 93  ALA B O   1 
ATOM 3440  C CB  . ALA B 1 93  ? -44.576 -39.277 37.591  1.00 88.43  ? 93  ALA B CB  1 
ATOM 3441  N N   . PHE B 1 94  ? -41.846 -37.187 37.454  1.00 83.59  ? 94  PHE B N   1 
ATOM 3442  C CA  . PHE B 1 94  ? -41.134 -36.144 36.675  1.00 79.41  ? 94  PHE B CA  1 
ATOM 3443  C C   . PHE B 1 94  ? -40.291 -36.851 35.609  1.00 73.15  ? 94  PHE B C   1 
ATOM 3444  O O   . PHE B 1 94  ? -40.167 -36.310 34.494  1.00 77.57  ? 94  PHE B O   1 
ATOM 3445  C CB  . PHE B 1 94  ? -40.279 -35.272 37.595  1.00 79.32  ? 94  PHE B CB  1 
ATOM 3446  C CG  . PHE B 1 94  ? -39.996 -33.887 37.069  1.00 71.00  ? 94  PHE B CG  1 
ATOM 3447  C CD1 . PHE B 1 94  ? -40.573 -33.442 35.891  1.00 68.25  ? 94  PHE B CD1 1 
ATOM 3448  C CD2 . PHE B 1 94  ? -39.152 -33.025 37.752  1.00 65.43  ? 94  PHE B CD2 1 
ATOM 3449  C CE1 . PHE B 1 94  ? -40.313 -32.171 35.407  1.00 72.87  ? 94  PHE B CE1 1 
ATOM 3450  C CE2 . PHE B 1 94  ? -38.893 -31.753 37.270  1.00 66.99  ? 94  PHE B CE2 1 
ATOM 3451  C CZ  . PHE B 1 94  ? -39.472 -31.328 36.097  1.00 73.66  ? 94  PHE B CZ  1 
ATOM 3452  N N   . GLU B 1 95  ? -39.751 -38.030 35.940  1.00 73.40  ? 95  GLU B N   1 
ATOM 3453  C CA  . GLU B 1 95  ? -38.872 -38.727 34.971  1.00 78.53  ? 95  GLU B CA  1 
ATOM 3454  C C   . GLU B 1 95  ? -39.737 -39.394 33.905  1.00 76.83  ? 95  GLU B C   1 
ATOM 3455  O O   . GLU B 1 95  ? -39.203 -40.215 33.147  1.00 79.88  ? 95  GLU B O   1 
ATOM 3456  C CB  . GLU B 1 95  ? -37.987 -39.736 35.696  1.00 88.26  ? 95  GLU B CB  1 
ATOM 3457  C CG  . GLU B 1 95  ? -36.849 -39.089 36.464  1.00 86.86  ? 95  GLU B CG  1 
ATOM 3458  C CD  . GLU B 1 95  ? -35.759 -38.479 35.600  1.00 82.94  ? 95  GLU B CD  1 
ATOM 3459  O OE1 . GLU B 1 95  ? -35.858 -38.578 34.363  1.00 88.04  ? 95  GLU B OE1 1 
ATOM 3460  O OE2 . GLU B 1 95  ? -34.810 -37.904 36.167  1.00 68.95  ? 95  GLU B OE2 1 
ATOM 3461  N N   . THR B 1 96  ? -41.022 -39.049 33.862  1.00 76.08  ? 96  THR B N   1 
ATOM 3462  C CA  . THR B 1 96  ? -41.930 -39.640 32.855  1.00 70.77  ? 96  THR B CA  1 
ATOM 3463  C C   . THR B 1 96  ? -42.624 -38.518 32.088  1.00 73.93  ? 96  THR B C   1 
ATOM 3464  O O   . THR B 1 96  ? -43.159 -38.786 31.009  1.00 80.06  ? 96  THR B O   1 
ATOM 3465  C CB  . THR B 1 96  ? -42.936 -40.564 33.542  1.00 77.05  ? 96  THR B CB  1 
ATOM 3466  O OG1 . THR B 1 96  ? -43.876 -39.745 34.236  1.00 78.27  ? 96  THR B OG1 1 
ATOM 3467  C CG2 . THR B 1 96  ? -42.282 -41.529 34.506  1.00 76.14  ? 96  THR B CG2 1 
ATOM 3468  N N   . ALA B 1 97  ? -42.595 -37.306 32.628  1.00 66.75  ? 97  ALA B N   1 
ATOM 3469  C CA  . ALA B 1 97  ? -43.325 -36.188 31.998  1.00 63.76  ? 97  ALA B CA  1 
ATOM 3470  C C   . ALA B 1 97  ? -42.446 -35.590 30.914  1.00 63.07  ? 97  ALA B C   1 
ATOM 3471  O O   . ALA B 1 97  ? -42.623 -34.418 30.584  1.00 66.51  ? 97  ALA B O   1 
ATOM 3472  C CB  . ALA B 1 97  ? -43.661 -35.163 33.035  1.00 60.40  ? 97  ALA B CB  1 
ATOM 3473  N N   . GLY B 1 98  ? -41.528 -36.383 30.393  1.00 64.98  ? 98  GLY B N   1 
ATOM 3474  C CA  . GLY B 1 98  ? -40.723 -35.869 29.281  1.00 63.01  ? 98  GLY B CA  1 
ATOM 3475  C C   . GLY B 1 98  ? -41.642 -35.378 28.192  1.00 57.48  ? 98  GLY B C   1 
ATOM 3476  O O   . GLY B 1 98  ? -41.711 -34.162 27.977  1.00 54.32  ? 98  GLY B O   1 
ATOM 3477  N N   . PRO B 1 99  ? -42.355 -36.279 27.491  1.00 54.56  ? 99  PRO B N   1 
ATOM 3478  C CA  . PRO B 1 99  ? -43.197 -35.841 26.364  1.00 54.97  ? 99  PRO B CA  1 
ATOM 3479  C C   . PRO B 1 99  ? -44.206 -34.769 26.733  1.00 53.56  ? 99  PRO B C   1 
ATOM 3480  O O   . PRO B 1 99  ? -44.612 -33.987 25.862  1.00 59.74  ? 99  PRO B O   1 
ATOM 3481  C CB  . PRO B 1 99  ? -43.887 -37.138 25.913  1.00 49.98  ? 99  PRO B CB  1 
ATOM 3482  C CG  . PRO B 1 99  ? -43.713 -38.097 27.050  1.00 59.84  ? 99  PRO B CG  1 
ATOM 3483  C CD  . PRO B 1 99  ? -42.416 -37.736 27.689  1.00 61.04  ? 99  PRO B CD  1 
ATOM 3484  N N   . THR B 1 100 ? -44.614 -34.684 27.999  1.00 51.96  ? 100 THR B N   1 
ATOM 3485  C CA  . THR B 1 100 ? -45.494 -33.594 28.412  1.00 51.18  ? 100 THR B CA  1 
ATOM 3486  C C   . THR B 1 100 ? -44.783 -32.252 28.294  1.00 52.50  ? 100 THR B C   1 
ATOM 3487  O O   . THR B 1 100 ? -45.330 -31.287 27.745  1.00 46.11  ? 100 THR B O   1 
ATOM 3488  C CB  . THR B 1 100 ? -45.977 -33.824 29.842  1.00 50.08  ? 100 THR B CB  1 
ATOM 3489  O OG1 . THR B 1 100 ? -46.425 -35.177 29.984  1.00 48.08  ? 100 THR B OG1 1 
ATOM 3490  C CG2 . THR B 1 100 ? -47.126 -32.882 30.165  1.00 51.80  ? 100 THR B CG2 1 
ATOM 3491  N N   . PHE B 1 101 ? -43.550 -32.176 28.795  1.00 56.04  ? 101 PHE B N   1 
ATOM 3492  C CA  . PHE B 1 101 ? -42.771 -30.954 28.638  1.00 54.21  ? 101 PHE B CA  1 
ATOM 3493  C C   . PHE B 1 101 ? -42.409 -30.713 27.179  1.00 51.70  ? 101 PHE B C   1 
ATOM 3494  O O   . PHE B 1 101 ? -42.276 -29.558 26.756  1.00 51.60  ? 101 PHE B O   1 
ATOM 3495  C CB  . PHE B 1 101 ? -41.515 -31.020 29.504  1.00 48.90  ? 101 PHE B CB  1 
ATOM 3496  C CG  . PHE B 1 101 ? -40.751 -29.730 29.561  1.00 54.71  ? 101 PHE B CG  1 
ATOM 3497  C CD1 . PHE B 1 101 ? -41.343 -28.581 30.058  1.00 53.27  ? 101 PHE B CD1 1 
ATOM 3498  C CD2 . PHE B 1 101 ? -39.437 -29.670 29.128  1.00 49.33  ? 101 PHE B CD2 1 
ATOM 3499  C CE1 . PHE B 1 101 ? -40.642 -27.394 30.115  1.00 51.69  ? 101 PHE B CE1 1 
ATOM 3500  C CE2 . PHE B 1 101 ? -38.730 -28.488 29.187  1.00 48.00  ? 101 PHE B CE2 1 
ATOM 3501  C CZ  . PHE B 1 101 ? -39.333 -27.347 29.680  1.00 44.40  ? 101 PHE B CZ  1 
ATOM 3502  N N   . SER B 1 102 ? -42.252 -31.783 26.397  1.00 49.29  ? 102 SER B N   1 
ATOM 3503  C CA  . SER B 1 102 ? -42.047 -31.621 24.962  1.00 53.99  ? 102 SER B CA  1 
ATOM 3504  C C   . SER B 1 102 ? -43.246 -30.936 24.318  1.00 55.86  ? 102 SER B C   1 
ATOM 3505  O O   . SER B 1 102 ? -43.082 -30.040 23.485  1.00 51.58  ? 102 SER B O   1 
ATOM 3506  C CB  . SER B 1 102 ? -41.787 -32.979 24.310  1.00 56.96  ? 102 SER B CB  1 
ATOM 3507  O OG  . SER B 1 102 ? -41.583 -32.841 22.915  1.00 54.99  ? 102 SER B OG  1 
ATOM 3508  N N   . GLU B 1 103 ? -44.459 -31.342 24.701  1.00 58.46  ? 103 GLU B N   1 
ATOM 3509  C CA  . GLU B 1 103 ? -45.663 -30.682 24.209  1.00 53.39  ? 103 GLU B CA  1 
ATOM 3510  C C   . GLU B 1 103 ? -45.725 -29.228 24.664  1.00 50.06  ? 103 GLU B C   1 
ATOM 3511  O O   . GLU B 1 103 ? -46.117 -28.338 23.895  1.00 48.19  ? 103 GLU B O   1 
ATOM 3512  C CB  . GLU B 1 103 ? -46.902 -31.444 24.683  1.00 50.05  ? 103 GLU B CB  1 
ATOM 3513  C CG  . GLU B 1 103 ? -48.214 -30.930 24.123  1.00 65.71  ? 103 GLU B CG  1 
ATOM 3514  C CD  . GLU B 1 103 ? -48.441 -31.353 22.683  1.00 72.20  ? 103 GLU B CD  1 
ATOM 3515  O OE1 . GLU B 1 103 ? -47.761 -32.297 22.225  1.00 58.85  ? 103 GLU B OE1 1 
ATOM 3516  O OE2 . GLU B 1 103 ? -49.299 -30.744 22.013  1.00 78.75  ? 103 GLU B OE2 1 
ATOM 3517  N N   . ILE B 1 104 ? -45.346 -28.968 25.918  1.00 55.97  ? 104 ILE B N   1 
ATOM 3518  C CA  . ILE B 1 104 ? -45.360 -27.595 26.423  1.00 51.64  ? 104 ILE B CA  1 
ATOM 3519  C C   . ILE B 1 104 ? -44.416 -26.716 25.611  1.00 51.00  ? 104 ILE B C   1 
ATOM 3520  O O   . ILE B 1 104 ? -44.765 -25.597 25.218  1.00 47.57  ? 104 ILE B O   1 
ATOM 3521  C CB  . ILE B 1 104 ? -45.018 -27.570 27.924  1.00 40.89  ? 104 ILE B CB  1 
ATOM 3522  C CG1 . ILE B 1 104 ? -46.237 -27.984 28.752  1.00 42.73  ? 104 ILE B CG1 1 
ATOM 3523  C CG2 . ILE B 1 104 ? -44.531 -26.192 28.343  1.00 51.03  ? 104 ILE B CG2 1 
ATOM 3524  C CD1 . ILE B 1 104 ? -46.074 -27.786 30.240  1.00 46.13  ? 104 ILE B CD1 1 
ATOM 3525  N N   . LEU B 1 105 ? -43.205 -27.212 25.340  1.00 49.15  ? 105 LEU B N   1 
ATOM 3526  C CA  . LEU B 1 105 ? -42.262 -26.448 24.528  1.00 47.20  ? 105 LEU B CA  1 
ATOM 3527  C C   . LEU B 1 105 ? -42.734 -26.331 23.085  1.00 56.57  ? 105 LEU B C   1 
ATOM 3528  O O   . LEU B 1 105 ? -42.474 -25.314 22.430  1.00 55.60  ? 105 LEU B O   1 
ATOM 3529  C CB  . LEU B 1 105 ? -40.875 -27.088 24.572  1.00 46.68  ? 105 LEU B CB  1 
ATOM 3530  C CG  . LEU B 1 105 ? -40.158 -27.162 25.922  1.00 44.69  ? 105 LEU B CG  1 
ATOM 3531  C CD1 . LEU B 1 105 ? -38.776 -27.772 25.739  1.00 47.28  ? 105 LEU B CD1 1 
ATOM 3532  C CD2 . LEU B 1 105 ? -40.061 -25.790 26.572  1.00 44.53  ? 105 LEU B CD2 1 
ATOM 3533  N N   . LYS B 1 106 ? -43.419 -27.355 22.575  1.00 57.97  ? 106 LYS B N   1 
ATOM 3534  C CA  . LYS B 1 106 ? -43.963 -27.299 21.224  1.00 55.75  ? 106 LYS B CA  1 
ATOM 3535  C C   . LYS B 1 106 ? -45.001 -26.195 21.099  1.00 56.62  ? 106 LYS B C   1 
ATOM 3536  O O   . LYS B 1 106 ? -45.095 -25.534 20.059  1.00 55.68  ? 106 LYS B O   1 
ATOM 3537  C CB  . LYS B 1 106 ? -44.568 -28.657 20.864  1.00 60.64  ? 106 LYS B CB  1 
ATOM 3538  C CG  . LYS B 1 106 ? -44.798 -28.890 19.390  1.00 57.08  ? 106 LYS B CG  1 
ATOM 3539  C CD  . LYS B 1 106 ? -45.343 -30.290 19.158  1.00 53.95  ? 106 LYS B CD  1 
ATOM 3540  C CE  . LYS B 1 106 ? -46.778 -30.422 19.649  1.00 57.50  ? 106 LYS B CE  1 
ATOM 3541  N NZ  . LYS B 1 106 ? -47.732 -29.621 18.829  1.00 48.61  ? 106 LYS B NZ  1 
ATOM 3542  N N   . THR B 1 107 ? -45.723 -25.941 22.193  1.00 55.76  ? 107 THR B N   1 
ATOM 3543  C CA  . THR B 1 107 ? -46.713 -24.832 22.200  1.00 52.14  ? 107 THR B CA  1 
ATOM 3544  C C   . THR B 1 107 ? -45.993 -23.515 22.515  1.00 55.10  ? 107 THR B C   1 
ATOM 3545  O O   . THR B 1 107 ? -46.144 -22.563 21.728  1.00 55.64  ? 107 THR B O   1 
ATOM 3546  C CB  . THR B 1 107 ? -47.833 -25.104 23.208  1.00 50.23  ? 107 THR B CB  1 
ATOM 3547  O OG1 . THR B 1 107 ? -48.441 -26.351 22.870  1.00 53.02  ? 107 THR B OG1 1 
ATOM 3548  C CG2 . THR B 1 107 ? -48.880 -24.011 23.234  1.00 52.57  ? 107 THR B CG2 1 
ATOM 3549  N N   . LEU B 1 108 ? -45.240 -23.470 23.621  1.00 59.16  ? 108 LEU B N   1 
ATOM 3550  C CA  . LEU B 1 108 ? -44.558 -22.215 24.041  1.00 56.42  ? 108 LEU B CA  1 
ATOM 3551  C C   . LEU B 1 108 ? -43.440 -21.859 23.055  1.00 57.63  ? 108 LEU B C   1 
ATOM 3552  O O   . LEU B 1 108 ? -43.388 -20.689 22.629  1.00 52.59  ? 108 LEU B O   1 
ATOM 3553  C CB  . LEU B 1 108 ? -43.993 -22.407 25.451  1.00 55.96  ? 108 LEU B CB  1 
ATOM 3554  C CG  . LEU B 1 108 ? -45.028 -22.660 26.546  1.00 59.29  ? 108 LEU B CG  1 
ATOM 3555  C CD1 . LEU B 1 108 ? -44.459 -22.318 27.912  1.00 62.53  ? 108 LEU B CD1 1 
ATOM 3556  C CD2 . LEU B 1 108 ? -46.298 -21.868 26.284  1.00 58.90  ? 108 LEU B CD2 1 
ATOM 3557  N N   . ASN B 1 109 ? -42.584 -22.827 22.718  1.00 61.13  ? 109 ASN B N   1 
ATOM 3558  C CA  . ASN B 1 109 ? -41.434 -22.561 21.807  1.00 63.69  ? 109 ASN B CA  1 
ATOM 3559  C C   . ASN B 1 109 ? -40.630 -21.370 22.347  1.00 58.37  ? 109 ASN B C   1 
ATOM 3560  O O   . ASN B 1 109 ? -40.607 -20.318 21.677  1.00 49.18  ? 109 ASN B O   1 
ATOM 3561  C CB  . ASN B 1 109 ? -41.896 -22.336 20.364  1.00 65.19  ? 109 ASN B CB  1 
ATOM 3562  C CG  . ASN B 1 109 ? -40.766 -22.438 19.361  1.00 78.37  ? 109 ASN B CG  1 
ATOM 3563  O OD1 . ASN B 1 109 ? -39.802 -21.681 19.420  1.00 79.46  ? 109 ASN B OD1 1 
ATOM 3564  N ND2 . ASN B 1 109 ? -40.880 -23.374 18.433  1.00 81.08  ? 109 ASN B ND2 1 
ATOM 3565  N N   . PRO B 1 110 ? -39.977 -21.487 23.525  1.00 48.30  ? 110 PRO B N   1 
ATOM 3566  C CA  . PRO B 1 110 ? -39.160 -20.399 24.077  1.00 55.59  ? 110 PRO B CA  1 
ATOM 3567  C C   . PRO B 1 110 ? -37.836 -20.243 23.317  1.00 59.53  ? 110 PRO B C   1 
ATOM 3568  O O   . PRO B 1 110 ? -37.388 -21.207 22.724  1.00 57.56  ? 110 PRO B O   1 
ATOM 3569  C CB  . PRO B 1 110 ? -38.881 -20.865 25.511  1.00 51.46  ? 110 PRO B CB  1 
ATOM 3570  C CG  . PRO B 1 110 ? -38.897 -22.372 25.407  1.00 49.40  ? 110 PRO B CG  1 
ATOM 3571  C CD  . PRO B 1 110 ? -39.975 -22.672 24.388  1.00 37.26  ? 110 PRO B CD  1 
ATOM 3572  N N   . ASP B 1 111 ? -37.247 -19.043 23.359  1.00 55.06  ? 111 ASP B N   1 
ATOM 3573  C CA  . ASP B 1 111 ? -35.953 -18.792 22.667  1.00 50.98  ? 111 ASP B CA  1 
ATOM 3574  C C   . ASP B 1 111 ? -34.821 -19.438 23.469  1.00 56.79  ? 111 ASP B C   1 
ATOM 3575  O O   . ASP B 1 111 ? -33.680 -19.449 22.964  1.00 56.73  ? 111 ASP B O   1 
ATOM 3576  C CB  . ASP B 1 111 ? -35.702 -17.293 22.486  1.00 52.61  ? 111 ASP B CB  1 
ATOM 3577  C CG  . ASP B 1 111 ? -36.843 -16.564 21.795  1.00 59.43  ? 111 ASP B CG  1 
ATOM 3578  O OD1 . ASP B 1 111 ? -37.824 -17.235 21.415  1.00 60.22  ? 111 ASP B OD1 1 
ATOM 3579  O OD2 . ASP B 1 111 ? -36.747 -15.329 21.652  1.00 57.82  ? 111 ASP B OD2 1 
ATOM 3580  N N   . LEU B 1 112 ? -35.123 -19.956 24.662  1.00 52.39  ? 112 LEU B N   1 
ATOM 3581  C CA  . LEU B 1 112 ? -34.094 -20.534 25.515  1.00 49.41  ? 112 LEU B CA  1 
ATOM 3582  C C   . LEU B 1 112 ? -34.750 -21.221 26.705  1.00 39.64  ? 112 LEU B C   1 
ATOM 3583  O O   . LEU B 1 112 ? -35.810 -20.801 27.172  1.00 44.03  ? 112 LEU B O   1 
ATOM 3584  C CB  . LEU B 1 112 ? -33.105 -19.461 25.986  1.00 45.88  ? 112 LEU B CB  1 
ATOM 3585  C CG  . LEU B 1 112 ? -31.819 -19.921 26.672  1.00 45.92  ? 112 LEU B CG  1 
ATOM 3586  C CD1 . LEU B 1 112 ? -30.671 -19.021 26.261  1.00 49.88  ? 112 LEU B CD1 1 
ATOM 3587  C CD2 . LEU B 1 112 ? -31.982 -19.918 28.183  1.00 42.51  ? 112 LEU B CD2 1 
ATOM 3588  N N   . LEU B 1 113 ? -34.103 -22.278 27.190  1.00 34.83  ? 113 LEU B N   1 
ATOM 3589  C CA  . LEU B 1 113 ? -34.581 -23.036 28.336  1.00 38.01  ? 113 LEU B CA  1 
ATOM 3590  C C   . LEU B 1 113 ? -33.554 -22.983 29.460  1.00 43.28  ? 113 LEU B C   1 
ATOM 3591  O O   . LEU B 1 113 ? -32.350 -23.128 29.221  1.00 42.57  ? 113 LEU B O   1 
ATOM 3592  C CB  . LEU B 1 113 ? -34.859 -24.495 27.958  1.00 36.31  ? 113 LEU B CB  1 
ATOM 3593  C CG  . LEU B 1 113 ? -35.203 -25.435 29.115  1.00 39.10  ? 113 LEU B CG  1 
ATOM 3594  C CD1 . LEU B 1 113 ? -36.492 -25.003 29.796  1.00 44.30  ? 113 LEU B CD1 1 
ATOM 3595  C CD2 . LEU B 1 113 ? -35.303 -26.875 28.641  1.00 42.73  ? 113 LEU B CD2 1 
ATOM 3596  N N   . ILE B 1 114 ? -34.032 -22.773 30.684  1.00 33.71  ? 114 ILE B N   1 
ATOM 3597  C CA  . ILE B 1 114 ? -33.194 -22.776 31.881  1.00 38.87  ? 114 ILE B CA  1 
ATOM 3598  C C   . ILE B 1 114 ? -33.679 -23.913 32.774  1.00 41.17  ? 114 ILE B C   1 
ATOM 3599  O O   . ILE B 1 114 ? -34.751 -23.817 33.386  1.00 39.99  ? 114 ILE B O   1 
ATOM 3600  C CB  . ILE B 1 114 ? -33.233 -21.434 32.619  1.00 37.16  ? 114 ILE B CB  1 
ATOM 3601  C CG1 . ILE B 1 114 ? -32.677 -20.322 31.731  1.00 38.55  ? 114 ILE B CG1 1 
ATOM 3602  C CG2 . ILE B 1 114 ? -32.452 -21.524 33.917  1.00 28.70  ? 114 ILE B CG2 1 
ATOM 3603  C CD1 . ILE B 1 114 ? -32.650 -18.958 32.388  1.00 33.67  ? 114 ILE B CD1 1 
ATOM 3604  N N   . TYR B 1 115 ? -32.884 -24.973 32.861  1.00 32.46  ? 115 TYR B N   1 
ATOM 3605  C CA  . TYR B 1 115 ? -33.267 -26.205 33.535  1.00 33.98  ? 115 TYR B CA  1 
ATOM 3606  C C   . TYR B 1 115 ? -32.495 -26.373 34.839  1.00 42.54  ? 115 TYR B C   1 
ATOM 3607  O O   . TYR B 1 115 ? -31.523 -25.665 35.118  1.00 41.30  ? 115 TYR B O   1 
ATOM 3608  C CB  . TYR B 1 115 ? -33.044 -27.411 32.614  1.00 37.39  ? 115 TYR B CB  1 
ATOM 3609  C CG  . TYR B 1 115 ? -31.604 -27.635 32.205  1.00 40.05  ? 115 TYR B CG  1 
ATOM 3610  C CD1 . TYR B 1 115 ? -31.027 -26.907 31.168  1.00 41.98  ? 115 TYR B CD1 1 
ATOM 3611  C CD2 . TYR B 1 115 ? -30.828 -28.593 32.842  1.00 45.03  ? 115 TYR B CD2 1 
ATOM 3612  C CE1 . TYR B 1 115 ? -29.710 -27.118 30.792  1.00 42.26  ? 115 TYR B CE1 1 
ATOM 3613  C CE2 . TYR B 1 115 ? -29.514 -28.812 32.473  1.00 44.53  ? 115 TYR B CE2 1 
ATOM 3614  C CZ  . TYR B 1 115 ? -28.962 -28.074 31.448  1.00 51.27  ? 115 TYR B CZ  1 
ATOM 3615  O OH  . TYR B 1 115 ? -27.650 -28.291 31.084  1.00 41.75  ? 115 TYR B OH  1 
ATOM 3616  N N   . ASP B 1 116 ? -32.948 -27.332 35.644  1.00 53.25  ? 116 ASP B N   1 
ATOM 3617  C CA  . ASP B 1 116 ? -32.348 -27.611 36.940  1.00 46.61  ? 116 ASP B CA  1 
ATOM 3618  C C   . ASP B 1 116 ? -31.465 -28.854 36.856  1.00 42.42  ? 116 ASP B C   1 
ATOM 3619  O O   . ASP B 1 116 ? -30.958 -29.194 35.783  1.00 47.52  ? 116 ASP B O   1 
ATOM 3620  C CB  . ASP B 1 116 ? -33.447 -27.770 38.000  1.00 47.87  ? 116 ASP B CB  1 
ATOM 3621  C CG  . ASP B 1 116 ? -33.020 -27.283 39.369  1.00 34.45  ? 116 ASP B CG  1 
ATOM 3622  O OD1 . ASP B 1 116 ? -31.806 -27.290 39.648  1.00 39.98  ? 116 ASP B OD1 1 
ATOM 3623  O OD2 . ASP B 1 116 ? -33.899 -26.893 40.165  1.00 30.25  ? 116 ASP B OD2 1 
ATOM 3624  N N   . PHE B 1 117 ? -31.283 -29.551 37.976  1.00 39.38  ? 117 PHE B N   1 
ATOM 3625  C CA  . PHE B 1 117 ? -30.274 -30.602 38.042  1.00 43.22  ? 117 PHE B CA  1 
ATOM 3626  C C   . PHE B 1 117 ? -30.823 -31.994 37.774  1.00 50.10  ? 117 PHE B C   1 
ATOM 3627  O O   . PHE B 1 117 ? -30.098 -32.847 37.243  1.00 60.62  ? 117 PHE B O   1 
ATOM 3628  C CB  . PHE B 1 117 ? -29.591 -30.596 39.411  1.00 43.33  ? 117 PHE B CB  1 
ATOM 3629  C CG  . PHE B 1 117 ? -30.499 -30.979 40.549  1.00 44.22  ? 117 PHE B CG  1 
ATOM 3630  C CD1 . PHE B 1 117 ? -31.327 -30.038 41.137  1.00 47.83  ? 117 PHE B CD1 1 
ATOM 3631  C CD2 . PHE B 1 117 ? -30.511 -32.275 41.040  1.00 41.48  ? 117 PHE B CD2 1 
ATOM 3632  C CE1 . PHE B 1 117 ? -32.156 -30.382 42.186  1.00 43.75  ? 117 PHE B CE1 1 
ATOM 3633  C CE2 . PHE B 1 117 ? -31.340 -32.626 42.090  1.00 41.88  ? 117 PHE B CE2 1 
ATOM 3634  C CZ  . PHE B 1 117 ? -32.162 -31.677 42.663  1.00 42.36  ? 117 PHE B CZ  1 
ATOM 3635  N N   . ASN B 1 118 ? -32.069 -32.250 38.136  1.00 54.07  ? 118 ASN B N   1 
ATOM 3636  C CA  . ASN B 1 118 ? -32.594 -33.608 38.098  1.00 59.84  ? 118 ASN B CA  1 
ATOM 3637  C C   . ASN B 1 118 ? -33.564 -33.913 36.958  1.00 60.54  ? 118 ASN B C   1 
ATOM 3638  O O   . ASN B 1 118 ? -33.741 -35.096 36.641  1.00 71.20  ? 118 ASN B O   1 
ATOM 3639  C CB  . ASN B 1 118 ? -33.290 -33.951 39.416  1.00 61.66  ? 118 ASN B CB  1 
ATOM 3640  C CG  . ASN B 1 118 ? -33.288 -35.441 39.686  1.00 70.79  ? 118 ASN B CG  1 
ATOM 3641  O OD1 . ASN B 1 118 ? -32.344 -36.137 39.313  1.00 66.79  ? 118 ASN B OD1 1 
ATOM 3642  N ND2 . ASN B 1 118 ? -34.343 -35.941 40.320  1.00 77.49  ? 118 ASN B ND2 1 
ATOM 3643  N N   . PRO B 1 119 ? -34.249 -32.926 36.356  1.00 48.52  ? 119 PRO B N   1 
ATOM 3644  C CA  . PRO B 1 119 ? -35.098 -33.247 35.192  1.00 50.62  ? 119 PRO B CA  1 
ATOM 3645  C C   . PRO B 1 119 ? -34.431 -34.140 34.147  1.00 54.07  ? 119 PRO B C   1 
ATOM 3646  O O   . PRO B 1 119 ? -35.137 -34.885 33.453  1.00 67.76  ? 119 PRO B O   1 
ATOM 3647  C CB  . PRO B 1 119 ? -35.458 -31.857 34.649  1.00 59.79  ? 119 PRO B CB  1 
ATOM 3648  C CG  . PRO B 1 119 ? -35.604 -31.032 35.899  1.00 59.04  ? 119 PRO B CG  1 
ATOM 3649  C CD  . PRO B 1 119 ? -34.563 -31.582 36.877  1.00 45.92  ? 119 PRO B CD  1 
ATOM 3650  N N   . SER B 1 120 ? -33.101 -34.146 34.042  1.00 57.22  ? 120 SER B N   1 
ATOM 3651  C CA  . SER B 1 120 ? -32.379 -35.101 33.144  1.00 53.98  ? 120 SER B CA  1 
ATOM 3652  C C   . SER B 1 120 ? -32.751 -34.975 31.661  1.00 61.67  ? 120 SER B C   1 
ATOM 3653  O O   . SER B 1 120 ? -31.848 -34.754 30.844  1.00 61.31  ? 120 SER B O   1 
ATOM 3654  C CB  . SER B 1 120 ? -32.589 -36.510 33.601  1.00 57.11  ? 120 SER B CB  1 
ATOM 3655  O OG  . SER B 1 120 ? -32.177 -37.432 32.608  1.00 62.74  ? 120 SER B OG  1 
ATOM 3656  N N   . TRP B 1 121 ? -34.018 -35.178 31.321  1.00 69.68  ? 121 TRP B N   1 
ATOM 3657  C CA  . TRP B 1 121 ? -34.450 -35.156 29.904  1.00 61.31  ? 121 TRP B CA  1 
ATOM 3658  C C   . TRP B 1 121 ? -34.585 -33.718 29.417  1.00 54.21  ? 121 TRP B C   1 
ATOM 3659  O O   . TRP B 1 121 ? -34.684 -33.511 28.203  1.00 55.56  ? 121 TRP B O   1 
ATOM 3660  C CB  . TRP B 1 121 ? -35.761 -35.928 29.752  1.00 64.40  ? 121 TRP B CB  1 
ATOM 3661  C CG  . TRP B 1 121 ? -36.814 -35.642 30.779  1.00 67.00  ? 121 TRP B CG  1 
ATOM 3662  C CD1 . TRP B 1 121 ? -37.276 -36.500 31.733  1.00 61.49  ? 121 TRP B CD1 1 
ATOM 3663  C CD2 . TRP B 1 121 ? -37.585 -34.438 30.920  1.00 67.70  ? 121 TRP B CD2 1 
ATOM 3664  N NE1 . TRP B 1 121 ? -38.256 -35.903 32.478  1.00 59.63  ? 121 TRP B NE1 1 
ATOM 3665  C CE2 . TRP B 1 121 ? -38.469 -34.638 32.002  1.00 61.39  ? 121 TRP B CE2 1 
ATOM 3666  C CE3 . TRP B 1 121 ? -37.609 -33.209 30.255  1.00 64.51  ? 121 TRP B CE3 1 
ATOM 3667  C CZ2 . TRP B 1 121 ? -39.360 -33.656 32.427  1.00 58.54  ? 121 TRP B CZ2 1 
ATOM 3668  C CZ3 . TRP B 1 121 ? -38.487 -32.238 30.678  1.00 68.60  ? 121 TRP B CZ3 1 
ATOM 3669  C CH2 . TRP B 1 121 ? -39.350 -32.460 31.748  1.00 56.39  ? 121 TRP B CH2 1 
ATOM 3670  N N   . ALA B 1 122 ? -34.573 -32.767 30.338  1.00 55.26  ? 122 ALA B N   1 
ATOM 3671  C CA  . ALA B 1 122 ? -34.768 -31.355 29.963  1.00 54.94  ? 122 ALA B CA  1 
ATOM 3672  C C   . ALA B 1 122 ? -33.784 -30.981 28.864  1.00 46.29  ? 122 ALA B C   1 
ATOM 3673  O O   . ALA B 1 122 ? -34.230 -30.515 27.815  1.00 49.48  ? 122 ALA B O   1 
ATOM 3674  C CB  . ALA B 1 122 ? -34.577 -30.498 31.181  1.00 56.42  ? 122 ALA B CB  1 
ATOM 3675  N N   . PRO B 1 123 ? -32.469 -31.170 29.054  1.00 52.04  ? 123 PRO B N   1 
ATOM 3676  C CA  . PRO B 1 123 ? -31.512 -30.741 28.047  1.00 53.56  ? 123 PRO B CA  1 
ATOM 3677  C C   . PRO B 1 123 ? -31.742 -31.479 26.719  1.00 52.08  ? 123 PRO B C   1 
ATOM 3678  O O   . PRO B 1 123 ? -31.587 -30.874 25.681  1.00 50.44  ? 123 PRO B O   1 
ATOM 3679  C CB  . PRO B 1 123 ? -30.163 -31.052 28.714  1.00 47.97  ? 123 PRO B CB  1 
ATOM 3680  C CG  . PRO B 1 123 ? -30.466 -32.116 29.731  1.00 63.02  ? 123 PRO B CG  1 
ATOM 3681  C CD  . PRO B 1 123 ? -31.844 -31.759 30.235  1.00 59.83  ? 123 PRO B CD  1 
ATOM 3682  N N   . GLU B 1 124 ? -32.140 -32.745 26.784  1.00 60.18  ? 124 GLU B N   1 
ATOM 3683  C CA  . GLU B 1 124 ? -32.323 -33.569 25.565  1.00 56.41  ? 124 GLU B CA  1 
ATOM 3684  C C   . GLU B 1 124 ? -33.573 -33.136 24.791  1.00 58.28  ? 124 GLU B C   1 
ATOM 3685  O O   . GLU B 1 124 ? -33.474 -33.005 23.564  1.00 56.58  ? 124 GLU B O   1 
ATOM 3686  C CB  . GLU B 1 124 ? -32.430 -35.029 25.994  1.00 53.65  ? 124 GLU B CB  1 
ATOM 3687  C CG  . GLU B 1 124 ? -31.544 -35.376 27.177  1.00 65.31  ? 124 GLU B CG  1 
ATOM 3688  C CD  . GLU B 1 124 ? -31.797 -36.741 27.795  1.00 73.31  ? 124 GLU B CD  1 
ATOM 3689  O OE1 . GLU B 1 124 ? -32.663 -37.471 27.280  1.00 73.12  ? 124 GLU B OE1 1 
ATOM 3690  O OE2 . GLU B 1 124 ? -31.134 -37.068 28.797  1.00 73.98  ? 124 GLU B OE2 1 
ATOM 3691  N N   . ILE B 1 125 ? -34.693 -32.932 25.479  1.00 55.75  ? 125 ILE B N   1 
ATOM 3692  C CA  . ILE B 1 125 ? -35.979 -32.553 24.829  1.00 49.60  ? 125 ILE B CA  1 
ATOM 3693  C C   . ILE B 1 125 ? -35.854 -31.142 24.261  1.00 52.26  ? 125 ILE B C   1 
ATOM 3694  O O   . ILE B 1 125 ? -36.480 -30.861 23.232  1.00 58.62  ? 125 ILE B O   1 
ATOM 3695  C CB  . ILE B 1 125 ? -37.140 -32.667 25.834  1.00 55.36  ? 125 ILE B CB  1 
ATOM 3696  C CG1 . ILE B 1 125 ? -37.714 -34.084 25.887  1.00 57.23  ? 125 ILE B CG1 1 
ATOM 3697  C CG2 . ILE B 1 125 ? -38.222 -31.642 25.535  1.00 57.09  ? 125 ILE B CG2 1 
ATOM 3698  C CD1 . ILE B 1 125 ? -36.814 -35.088 26.564  1.00 61.68  ? 125 ILE B CD1 1 
ATOM 3699  N N   . ALA B 1 126 ? -35.062 -30.293 24.908  1.00 51.23  ? 126 ALA B N   1 
ATOM 3700  C CA  . ALA B 1 126 ? -34.868 -28.910 24.424  1.00 53.89  ? 126 ALA B CA  1 
ATOM 3701  C C   . ALA B 1 126 ? -34.119 -28.929 23.093  1.00 53.45  ? 126 ALA B C   1 
ATOM 3702  O O   . ALA B 1 126 ? -34.448 -28.129 22.208  1.00 54.50  ? 126 ALA B O   1 
ATOM 3703  C CB  . ALA B 1 126 ? -34.102 -28.146 25.456  1.00 45.20  ? 126 ALA B CB  1 
ATOM 3704  N N   . SER B 1 127 ? -33.136 -29.809 22.979  1.00 45.50  ? 127 SER B N   1 
ATOM 3705  C CA  . SER B 1 127 ? -32.335 -29.908 21.741  1.00 54.12  ? 127 SER B CA  1 
ATOM 3706  C C   . SER B 1 127 ? -33.165 -30.534 20.618  1.00 58.61  ? 127 SER B C   1 
ATOM 3707  O O   . SER B 1 127 ? -32.853 -30.284 19.453  1.00 57.63  ? 127 SER B O   1 
ATOM 3708  C CB  . SER B 1 127 ? -31.095 -30.693 22.020  1.00 55.97  ? 127 SER B CB  1 
ATOM 3709  O OG  . SER B 1 127 ? -30.448 -30.200 23.181  1.00 68.64  ? 127 SER B OG  1 
ATOM 3710  N N   . SER B 1 128 ? -34.166 -31.329 20.968  1.00 60.33  ? 128 SER B N   1 
ATOM 3711  C CA  . SER B 1 128 ? -35.059 -31.931 19.957  1.00 57.37  ? 128 SER B CA  1 
ATOM 3712  C C   . SER B 1 128 ? -35.972 -30.851 19.387  1.00 56.09  ? 128 SER B C   1 
ATOM 3713  O O   . SER B 1 128 ? -36.617 -31.099 18.366  1.00 61.50  ? 128 SER B O   1 
ATOM 3714  C CB  . SER B 1 128 ? -35.844 -33.031 20.567  1.00 56.92  ? 128 SER B CB  1 
ATOM 3715  O OG  . SER B 1 128 ? -36.775 -32.521 21.504  1.00 59.67  ? 128 SER B OG  1 
ATOM 3716  N N   . HIS B 1 129 ? -36.052 -29.707 20.049  1.00 49.69  ? 129 HIS B N   1 
ATOM 3717  C CA  . HIS B 1 129 ? -36.835 -28.579 19.494  1.00 49.39  ? 129 HIS B CA  1 
ATOM 3718  C C   . HIS B 1 129 ? -35.848 -27.493 19.064  1.00 49.96  ? 129 HIS B C   1 
ATOM 3719  O O   . HIS B 1 129 ? -36.288 -26.367 18.772  1.00 39.93  ? 129 HIS B O   1 
ATOM 3720  C CB  . HIS B 1 129 ? -37.864 -28.086 20.511  1.00 53.89  ? 129 HIS B CB  1 
ATOM 3721  C CG  . HIS B 1 129 ? -38.877 -29.090 20.948  1.00 60.53  ? 129 HIS B CG  1 
ATOM 3722  N ND1 . HIS B 1 129 ? -40.217 -28.954 20.659  1.00 51.05  ? 129 HIS B ND1 1 
ATOM 3723  C CD2 . HIS B 1 129 ? -38.762 -30.225 21.639  1.00 59.43  ? 129 HIS B CD2 1 
ATOM 3724  C CE1 . HIS B 1 129 ? -40.876 -29.981 21.166  1.00 56.99  ? 129 HIS B CE1 1 
ATOM 3725  N NE2 . HIS B 1 129 ? -40.011 -30.765 21.766  1.00 55.24  ? 129 HIS B NE2 1 
ATOM 3726  N N   . ASN B 1 130 ? -34.554 -27.821 19.035  1.00 55.34  ? 130 ASN B N   1 
ATOM 3727  C CA  . ASN B 1 130 ? -33.492 -26.864 18.627  1.00 55.72  ? 130 ASN B CA  1 
ATOM 3728  C C   . ASN B 1 130 ? -33.522 -25.682 19.589  1.00 52.30  ? 130 ASN B C   1 
ATOM 3729  O O   . ASN B 1 130 ? -33.328 -24.550 19.133  1.00 50.15  ? 130 ASN B O   1 
ATOM 3730  C CB  . ASN B 1 130 ? -33.621 -26.496 17.148  1.00 58.46  ? 130 ASN B CB  1 
ATOM 3731  C CG  . ASN B 1 130 ? -32.359 -25.897 16.564  1.00 62.44  ? 130 ASN B CG  1 
ATOM 3732  O OD1 . ASN B 1 130 ? -31.298 -26.515 16.603  1.00 63.75  ? 130 ASN B OD1 1 
ATOM 3733  N ND2 . ASN B 1 130 ? -32.466 -24.699 16.016  1.00 56.04  ? 130 ASN B ND2 1 
ATOM 3734  N N   . ILE B 1 131 ? -33.752 -25.955 20.874  1.00 51.90  ? 131 ILE B N   1 
ATOM 3735  C CA  . ILE B 1 131 ? -33.743 -24.894 21.875  1.00 47.69  ? 131 ILE B CA  1 
ATOM 3736  C C   . ILE B 1 131 ? -32.449 -25.011 22.673  1.00 46.85  ? 131 ILE B C   1 
ATOM 3737  O O   . ILE B 1 131 ? -32.191 -26.069 23.264  1.00 49.18  ? 131 ILE B O   1 
ATOM 3738  C CB  . ILE B 1 131 ? -34.967 -24.972 22.798  1.00 45.89  ? 131 ILE B CB  1 
ATOM 3739  C CG1 . ILE B 1 131 ? -36.258 -24.863 21.990  1.00 41.21  ? 131 ILE B CG1 1 
ATOM 3740  C CG2 . ILE B 1 131 ? -34.915 -23.873 23.847  1.00 54.12  ? 131 ILE B CG2 1 
ATOM 3741  C CD1 . ILE B 1 131 ? -37.500 -24.923 22.839  1.00 52.97  ? 131 ILE B CD1 1 
ATOM 3742  N N   . PRO B 1 132 ? -31.618 -23.973 22.721  1.00 47.42  ? 132 PRO B N   1 
ATOM 3743  C CA  . PRO B 1 132 ? -30.410 -24.042 23.553  1.00 50.72  ? 132 PRO B CA  1 
ATOM 3744  C C   . PRO B 1 132 ? -30.768 -24.093 25.030  1.00 41.36  ? 132 PRO B C   1 
ATOM 3745  O O   . PRO B 1 132 ? -31.648 -23.372 25.502  1.00 38.00  ? 132 PRO B O   1 
ATOM 3746  C CB  . PRO B 1 132 ? -29.661 -22.752 23.199  1.00 54.95  ? 132 PRO B CB  1 
ATOM 3747  C CG  . PRO B 1 132 ? -30.723 -21.825 22.711  1.00 58.35  ? 132 PRO B CG  1 
ATOM 3748  C CD  . PRO B 1 132 ? -31.730 -22.690 22.010  1.00 49.51  ? 132 PRO B CD  1 
ATOM 3749  N N   . ALA B 1 133 ? -30.073 -24.962 25.755  1.00 41.63  ? 133 ALA B N   1 
ATOM 3750  C CA  . ALA B 1 133 ? -30.360 -25.232 27.158  1.00 36.69  ? 133 ALA B CA  1 
ATOM 3751  C C   . ALA B 1 133 ? -29.222 -24.716 28.029  1.00 32.70  ? 133 ALA B C   1 
ATOM 3752  O O   . ALA B 1 133 ? -28.055 -25.049 27.796  1.00 35.04  ? 133 ALA B O   1 
ATOM 3753  C CB  . ALA B 1 133 ? -30.569 -26.728 27.387  1.00 50.57  ? 133 ALA B CB  1 
ATOM 3754  N N   . VAL B 1 134 ? -29.567 -23.906 29.029  1.00 36.28  ? 134 VAL B N   1 
ATOM 3755  C CA  . VAL B 1 134 ? -28.609 -23.349 29.978  1.00 40.05  ? 134 VAL B CA  1 
ATOM 3756  C C   . VAL B 1 134 ? -28.958 -23.858 31.371  1.00 33.83  ? 134 VAL B C   1 
ATOM 3757  O O   . VAL B 1 134 ? -30.129 -23.867 31.763  1.00 40.41  ? 134 VAL B O   1 
ATOM 3758  C CB  . VAL B 1 134 ? -28.608 -21.806 29.949  1.00 37.61  ? 134 VAL B CB  1 
ATOM 3759  C CG1 . VAL B 1 134 ? -27.753 -21.246 31.079  1.00 31.26  ? 134 VAL B CG1 1 
ATOM 3760  C CG2 . VAL B 1 134 ? -28.115 -21.299 28.601  1.00 34.95  ? 134 VAL B CG2 1 
ATOM 3761  N N   . TYR B 1 135 ? -27.937 -24.274 32.116  1.00 40.00  ? 135 TYR B N   1 
ATOM 3762  C CA  . TYR B 1 135 ? -28.127 -24.834 33.449  1.00 38.33  ? 135 TYR B CA  1 
ATOM 3763  C C   . TYR B 1 135 ? -28.067 -23.742 34.511  1.00 32.94  ? 135 TYR B C   1 
ATOM 3764  O O   . TYR B 1 135 ? -27.267 -22.806 34.420  1.00 37.91  ? 135 TYR B O   1 
ATOM 3765  C CB  . TYR B 1 135 ? -27.067 -25.903 33.727  1.00 40.80  ? 135 TYR B CB  1 
ATOM 3766  C CG  . TYR B 1 135 ? -27.042 -26.429 35.147  1.00 44.84  ? 135 TYR B CG  1 
ATOM 3767  C CD1 . TYR B 1 135 ? -28.153 -27.048 35.704  1.00 47.23  ? 135 TYR B CD1 1 
ATOM 3768  C CD2 . TYR B 1 135 ? -25.891 -26.336 35.919  1.00 48.46  ? 135 TYR B CD2 1 
ATOM 3769  C CE1 . TYR B 1 135 ? -28.124 -27.538 36.999  1.00 45.30  ? 135 TYR B CE1 1 
ATOM 3770  C CE2 . TYR B 1 135 ? -25.852 -26.825 37.209  1.00 48.01  ? 135 TYR B CE2 1 
ATOM 3771  C CZ  . TYR B 1 135 ? -26.968 -27.427 37.746  1.00 51.23  ? 135 TYR B CZ  1 
ATOM 3772  O OH  . TYR B 1 135 ? -26.935 -27.914 39.033  1.00 41.48  ? 135 TYR B OH  1 
ATOM 3773  N N   . PHE B 1 136 ? -28.925 -23.872 35.520  1.00 35.11  ? 136 PHE B N   1 
ATOM 3774  C CA  . PHE B 1 136 ? -29.002 -22.941 36.640  1.00 38.94  ? 136 PHE B CA  1 
ATOM 3775  C C   . PHE B 1 136 ? -28.589 -23.691 37.902  1.00 41.30  ? 136 PHE B C   1 
ATOM 3776  O O   . PHE B 1 136 ? -29.311 -24.578 38.367  1.00 51.61  ? 136 PHE B O   1 
ATOM 3777  C CB  . PHE B 1 136 ? -30.410 -22.365 36.778  1.00 34.73  ? 136 PHE B CB  1 
ATOM 3778  C CG  . PHE B 1 136 ? -30.536 -21.279 37.813  1.00 36.67  ? 136 PHE B CG  1 
ATOM 3779  C CD1 . PHE B 1 136 ? -29.416 -20.614 38.291  1.00 41.25  ? 136 PHE B CD1 1 
ATOM 3780  C CD2 . PHE B 1 136 ? -31.778 -20.925 38.313  1.00 33.97  ? 136 PHE B CD2 1 
ATOM 3781  C CE1 . PHE B 1 136 ? -29.537 -19.620 39.245  1.00 37.80  ? 136 PHE B CE1 1 
ATOM 3782  C CE2 . PHE B 1 136 ? -31.903 -19.934 39.265  1.00 44.72  ? 136 PHE B CE2 1 
ATOM 3783  C CZ  . PHE B 1 136 ? -30.782 -19.280 39.733  1.00 40.87  ? 136 PHE B CZ  1 
ATOM 3784  N N   . LEU B 1 137 ? -27.434 -23.330 38.456  1.00 36.96  ? 137 LEU B N   1 
ATOM 3785  C CA  . LEU B 1 137 ? -26.913 -23.944 39.672  1.00 42.34  ? 137 LEU B CA  1 
ATOM 3786  C C   . LEU B 1 137 ? -27.241 -23.032 40.849  1.00 43.35  ? 137 LEU B C   1 
ATOM 3787  O O   . LEU B 1 137 ? -26.763 -21.896 40.913  1.00 41.92  ? 137 LEU B O   1 
ATOM 3788  C CB  . LEU B 1 137 ? -25.406 -24.174 39.558  1.00 43.73  ? 137 LEU B CB  1 
ATOM 3789  C CG  . LEU B 1 137 ? -24.687 -24.796 40.753  1.00 35.23  ? 137 LEU B CG  1 
ATOM 3790  C CD1 . LEU B 1 137 ? -24.666 -26.314 40.651  1.00 45.37  ? 137 LEU B CD1 1 
ATOM 3791  C CD2 . LEU B 1 137 ? -23.279 -24.240 40.866  1.00 43.58  ? 137 LEU B CD2 1 
ATOM 3792  N N   . THR B 1 138 ? -28.058 -23.529 41.776  1.00 42.23  ? 138 THR B N   1 
ATOM 3793  C CA  . THR B 1 138 ? -28.474 -22.758 42.940  1.00 42.31  ? 138 THR B CA  1 
ATOM 3794  C C   . THR B 1 138 ? -27.629 -23.053 44.170  1.00 40.51  ? 138 THR B C   1 
ATOM 3795  O O   . THR B 1 138 ? -28.018 -22.683 45.280  1.00 46.78  ? 138 THR B O   1 
ATOM 3796  C CB  . THR B 1 138 ? -29.947 -23.024 43.256  1.00 41.59  ? 138 THR B CB  1 
ATOM 3797  O OG1 . THR B 1 138 ? -30.122 -24.403 43.600  1.00 47.60  ? 138 THR B OG1 1 
ATOM 3798  C CG2 . THR B 1 138 ? -30.809 -22.699 42.044  1.00 43.57  ? 138 THR B CG2 1 
ATOM 3799  N N   . THR B 1 139 ? -26.488 -23.708 43.991  1.00 45.56  ? 139 THR B N   1 
ATOM 3800  C CA  . THR B 1 139 ? -25.602 -24.092 45.077  1.00 34.26  ? 139 THR B CA  1 
ATOM 3801  C C   . THR B 1 139 ? -24.260 -23.389 44.892  1.00 41.48  ? 139 THR B C   1 
ATOM 3802  O O   . THR B 1 139 ? -23.949 -22.878 43.814  1.00 35.27  ? 139 THR B O   1 
ATOM 3803  C CB  . THR B 1 139 ? -25.429 -25.621 45.108  1.00 37.02  ? 139 THR B CB  1 
ATOM 3804  O OG1 . THR B 1 139 ? -26.711 -26.244 44.960  1.00 49.01  ? 139 THR B OG1 1 
ATOM 3805  C CG2 . THR B 1 139 ? -24.816 -26.083 46.417  1.00 62.09  ? 139 THR B CG2 1 
ATOM 3806  N N   . ALA B 1 140 ? -23.481 -23.345 45.971  1.00 47.08  ? 140 ALA B N   1 
ATOM 3807  C CA  . ALA B 1 140 ? -22.150 -22.756 45.918  1.00 40.55  ? 140 ALA B CA  1 
ATOM 3808  C C   . ALA B 1 140 ? -21.292 -23.448 44.866  1.00 47.43  ? 140 ALA B C   1 
ATOM 3809  O O   . ALA B 1 140 ? -21.460 -24.637 44.575  1.00 50.08  ? 140 ALA B O   1 
ATOM 3810  C CB  . ALA B 1 140 ? -21.473 -22.853 47.285  1.00 43.36  ? 140 ALA B CB  1 
ATOM 3811  N N   . ALA B 1 141 ? -20.359 -22.688 44.291  1.00 49.22  ? 141 ALA B N   1 
ATOM 3812  C CA  . ALA B 1 141 ? -19.505 -23.232 43.243  1.00 44.78  ? 141 ALA B CA  1 
ATOM 3813  C C   . ALA B 1 141 ? -18.494 -24.231 43.792  1.00 46.22  ? 141 ALA B C   1 
ATOM 3814  O O   . ALA B 1 141 ? -18.125 -25.176 43.090  1.00 46.60  ? 141 ALA B O   1 
ATOM 3815  C CB  . ALA B 1 141 ? -18.786 -22.103 42.508  1.00 45.03  ? 141 ALA B CB  1 
ATOM 3816  N N   . ALA B 1 142 ? -18.038 -24.047 45.035  1.00 42.13  ? 142 ALA B N   1 
ATOM 3817  C CA  . ALA B 1 142 ? -17.003 -24.920 45.582  1.00 42.63  ? 142 ALA B CA  1 
ATOM 3818  C C   . ALA B 1 142 ? -17.528 -26.327 45.836  1.00 42.37  ? 142 ALA B C   1 
ATOM 3819  O O   . ALA B 1 142 ? -16.851 -27.321 45.530  1.00 43.17  ? 142 ALA B O   1 
ATOM 3820  C CB  . ALA B 1 142 ? -16.451 -24.324 46.877  1.00 45.91  ? 142 ALA B CB  1 
ATOM 3821  N N   . SER B 1 143 ? -18.724 -26.428 46.419  1.00 45.99  ? 143 SER B N   1 
ATOM 3822  C CA  . SER B 1 143 ? -19.295 -27.730 46.737  1.00 46.70  ? 143 SER B CA  1 
ATOM 3823  C C   . SER B 1 143 ? -19.466 -28.576 45.482  1.00 51.84  ? 143 SER B C   1 
ATOM 3824  O O   . SER B 1 143 ? -19.225 -29.787 45.504  1.00 50.27  ? 143 SER B O   1 
ATOM 3825  C CB  . SER B 1 143 ? -20.628 -27.547 47.457  1.00 51.96  ? 143 SER B CB  1 
ATOM 3826  O OG  . SER B 1 143 ? -20.479 -26.675 48.566  1.00 64.39  ? 143 SER B OG  1 
ATOM 3827  N N   . SER B 1 144 ? -19.875 -27.951 44.375  1.00 58.06  ? 144 SER B N   1 
ATOM 3828  C CA  . SER B 1 144 ? -19.977 -28.676 43.113  1.00 41.76  ? 144 SER B CA  1 
ATOM 3829  C C   . SER B 1 144 ? -18.604 -28.928 42.503  1.00 41.24  ? 144 SER B C   1 
ATOM 3830  O O   . SER B 1 144 ? -18.385 -29.966 41.865  1.00 43.94  ? 144 SER B O   1 
ATOM 3831  C CB  . SER B 1 144 ? -20.854 -27.901 42.133  1.00 44.72  ? 144 SER B CB  1 
ATOM 3832  O OG  . SER B 1 144 ? -22.087 -27.538 42.730  1.00 52.40  ? 144 SER B OG  1 
ATOM 3833  N N   . SER B 1 145 ? -17.681 -27.974 42.684  1.00 41.89  ? 145 SER B N   1 
ATOM 3834  C CA  . SER B 1 145 ? -16.317 -28.125 42.188  1.00 45.21  ? 145 SER B CA  1 
ATOM 3835  C C   . SER B 1 145 ? -15.653 -29.363 42.756  1.00 51.78  ? 145 SER B C   1 
ATOM 3836  O O   . SER B 1 145 ? -14.846 -29.996 42.069  1.00 50.95  ? 145 SER B O   1 
ATOM 3837  C CB  . SER B 1 145 ? -15.499 -26.880 42.533  1.00 46.91  ? 145 SER B CB  1 
ATOM 3838  O OG  . SER B 1 145 ? -16.051 -25.725 41.926  1.00 69.68  ? 145 SER B OG  1 
ATOM 3839  N N   . ILE B 1 146 ? -15.975 -29.720 43.999  1.00 51.53  ? 146 ILE B N   1 
ATOM 3840  C CA  . ILE B 1 146 ? -15.459 -30.944 44.614  1.00 43.99  ? 146 ILE B CA  1 
ATOM 3841  C C   . ILE B 1 146 ? -15.658 -32.123 43.666  1.00 50.32  ? 146 ILE B C   1 
ATOM 3842  O O   . ILE B 1 146 ? -14.691 -32.687 43.132  1.00 45.23  ? 146 ILE B O   1 
ATOM 3843  C CB  . ILE B 1 146 ? -16.138 -31.215 45.970  1.00 46.12  ? 146 ILE B CB  1 
ATOM 3844  C CG1 . ILE B 1 146 ? -15.951 -30.025 46.916  1.00 56.82  ? 146 ILE B CG1 1 
ATOM 3845  C CG2 . ILE B 1 146 ? -15.586 -32.481 46.600  1.00 48.79  ? 146 ILE B CG2 1 
ATOM 3846  C CD1 . ILE B 1 146 ? -14.511 -29.647 47.144  1.00 60.80  ? 146 ILE B CD1 1 
ATOM 3847  N N   . GLY B 1 147 ? -16.922 -32.485 43.430  1.00 54.59  ? 147 GLY B N   1 
ATOM 3848  C CA  . GLY B 1 147 ? -17.214 -33.629 42.584  1.00 56.09  ? 147 GLY B CA  1 
ATOM 3849  C C   . GLY B 1 147 ? -16.825 -33.434 41.132  1.00 52.16  ? 147 GLY B C   1 
ATOM 3850  O O   . GLY B 1 147 ? -16.398 -34.387 40.467  1.00 53.02  ? 147 GLY B O   1 
ATOM 3851  N N   . LEU B 1 148 ? -16.961 -32.212 40.612  1.00 50.51  ? 148 LEU B N   1 
ATOM 3852  C CA  . LEU B 1 148 ? -16.623 -31.997 39.208  1.00 50.26  ? 148 LEU B CA  1 
ATOM 3853  C C   . LEU B 1 148 ? -15.129 -32.187 38.970  1.00 53.75  ? 148 LEU B C   1 
ATOM 3854  O O   . LEU B 1 148 ? -14.723 -32.715 37.927  1.00 55.25  ? 148 LEU B O   1 
ATOM 3855  C CB  . LEU B 1 148 ? -17.068 -30.610 38.754  1.00 43.36  ? 148 LEU B CB  1 
ATOM 3856  C CG  . LEU B 1 148 ? -17.206 -30.458 37.238  1.00 52.36  ? 148 LEU B CG  1 
ATOM 3857  C CD1 . LEU B 1 148 ? -18.110 -31.543 36.668  1.00 51.38  ? 148 LEU B CD1 1 
ATOM 3858  C CD2 . LEU B 1 148 ? -17.742 -29.080 36.890  1.00 48.67  ? 148 LEU B CD2 1 
ATOM 3859  N N   . HIS B 1 149 ? -14.280 -31.829 39.935  1.00 50.56  ? 149 HIS B N   1 
ATOM 3860  C CA  . HIS B 1 149 ? -12.812 -32.046 39.791  1.00 53.28  ? 149 HIS B CA  1 
ATOM 3861  C C   . HIS B 1 149 ? -12.497 -33.532 39.838  1.00 58.22  ? 149 HIS B C   1 
ATOM 3862  O O   . HIS B 1 149 ? -11.667 -33.974 39.062  1.00 55.55  ? 149 HIS B O   1 
ATOM 3863  C CB  . HIS B 1 149 ? -12.043 -31.359 40.920  1.00 54.45  ? 149 HIS B CB  1 
ATOM 3864  C CG  . HIS B 1 149 ? -10.567 -31.547 40.880  1.00 52.08  ? 149 HIS B CG  1 
ATOM 3865  N ND1 . HIS B 1 149 ? -9.736  -30.665 40.231  1.00 60.53  ? 149 HIS B ND1 1 
ATOM 3866  C CD2 . HIS B 1 149 ? -9.773  -32.492 41.418  1.00 57.60  ? 149 HIS B CD2 1 
ATOM 3867  C CE1 . HIS B 1 149 ? -8.492  -31.067 40.358  1.00 71.16  ? 149 HIS B CE1 1 
ATOM 3868  N NE2 . HIS B 1 149 ? -8.491  -32.187 41.074  1.00 62.81  ? 149 HIS B NE2 1 
ATOM 3869  N N   . ALA B 1 150 ? -13.174 -34.257 40.706  1.00 65.01  ? 150 ALA B N   1 
ATOM 3870  C CA  . ALA B 1 150 ? -12.893 -35.691 40.902  1.00 63.07  ? 150 ALA B CA  1 
ATOM 3871  C C   . ALA B 1 150 ? -13.154 -36.453 39.611  1.00 65.94  ? 150 ALA B C   1 
ATOM 3872  O O   . ALA B 1 150 ? -12.649 -37.567 39.473  1.00 70.33  ? 150 ALA B O   1 
ATOM 3873  C CB  . ALA B 1 150 ? -13.766 -36.207 42.001  1.00 48.63  ? 150 ALA B CB  1 
ATOM 3874  N N   . PHE B 1 151 ? -13.920 -35.845 38.700  1.00 65.86  ? 151 PHE B N   1 
ATOM 3875  C CA  . PHE B 1 151 ? -14.209 -36.473 37.386  1.00 67.71  ? 151 PHE B CA  1 
ATOM 3876  C C   . PHE B 1 151 ? -13.267 -35.874 36.339  1.00 71.09  ? 151 PHE B C   1 
ATOM 3877  O O   . PHE B 1 151 ? -12.600 -36.645 35.622  1.00 77.48  ? 151 PHE B O   1 
ATOM 3878  C CB  . PHE B 1 151 ? -15.673 -36.247 37.009  1.00 61.26  ? 151 PHE B CB  1 
ATOM 3879  C CG  . PHE B 1 151 ? -16.018 -36.586 35.581  1.00 67.79  ? 151 PHE B CG  1 
ATOM 3880  C CD1 . PHE B 1 151 ? -15.869 -37.877 35.101  1.00 77.83  ? 151 PHE B CD1 1 
ATOM 3881  C CD2 . PHE B 1 151 ? -16.485 -35.611 34.715  1.00 73.22  ? 151 PHE B CD2 1 
ATOM 3882  C CE1 . PHE B 1 151 ? -16.185 -38.184 33.789  1.00 83.86  ? 151 PHE B CE1 1 
ATOM 3883  C CE2 . PHE B 1 151 ? -16.798 -35.921 33.401  1.00 78.22  ? 151 PHE B CE2 1 
ATOM 3884  C CZ  . PHE B 1 151 ? -16.648 -37.206 32.940  1.00 68.97  ? 151 PHE B CZ  1 
ATOM 3885  N N   . LYS B 1 152 ? -13.286 -34.568 36.178  1.00 66.88  ? 152 LYS B N   1 
ATOM 3886  C CA  . LYS B 1 152 ? -12.474 -34.024 35.070  1.00 72.44  ? 152 LYS B CA  1 
ATOM 3887  C C   . LYS B 1 152 ? -11.013 -34.403 35.301  1.00 72.34  ? 152 LYS B C   1 
ATOM 3888  O O   . LYS B 1 152 ? -10.372 -34.895 34.358  1.00 82.88  ? 152 LYS B O   1 
ATOM 3889  C CB  . LYS B 1 152 ? -12.764 -32.537 34.876  1.00 73.58  ? 152 LYS B CB  1 
ATOM 3890  C CG  . LYS B 1 152 ? -14.217 -32.203 34.582  1.00 70.80  ? 152 LYS B CG  1 
ATOM 3891  C CD  . LYS B 1 152 ? -14.690 -32.742 33.256  1.00 68.39  ? 152 LYS B CD  1 
ATOM 3892  C CE  . LYS B 1 152 ? -16.158 -32.480 33.011  1.00 76.74  ? 152 LYS B CE  1 
ATOM 3893  N NZ  . LYS B 1 152 ? -16.531 -31.091 33.363  1.00 71.07  ? 152 LYS B NZ  1 
ATOM 3894  N N   . ASN B 1 153 ? -10.515 -34.177 36.510  1.00 69.60  ? 153 ASN B N   1 
ATOM 3895  C CA  . ASN B 1 153 ? -9.093  -34.466 36.814  1.00 64.84  ? 153 ASN B CA  1 
ATOM 3896  C C   . ASN B 1 153 ? -9.098  -35.532 37.902  1.00 68.89  ? 153 ASN B C   1 
ATOM 3897  O O   . ASN B 1 153 ? -9.052  -35.170 39.083  1.00 66.75  ? 153 ASN B O   1 
ATOM 3898  C CB  . ASN B 1 153 ? -8.391  -33.166 37.193  1.00 56.98  ? 153 ASN B CB  1 
ATOM 3899  C CG  . ASN B 1 153 ? -8.509  -32.107 36.121  1.00 68.96  ? 153 ASN B CG  1 
ATOM 3900  O OD1 . ASN B 1 153 ? -8.482  -32.412 34.933  1.00 77.15  ? 153 ASN B OD1 1 
ATOM 3901  N ND2 . ASN B 1 153 ? -8.631  -30.857 36.532  1.00 74.86  ? 153 ASN B ND2 1 
ATOM 3902  N N   . PRO B 1 154 ? -9.031  -36.833 37.567  1.00 66.06  ? 154 PRO B N   1 
ATOM 3903  C CA  . PRO B 1 154 ? -9.210  -37.869 38.580  1.00 67.30  ? 154 PRO B CA  1 
ATOM 3904  C C   . PRO B 1 154 ? -8.243  -37.876 39.768  1.00 74.20  ? 154 PRO B C   1 
ATOM 3905  O O   . PRO B 1 154 ? -8.712  -38.016 40.869  1.00 77.69  ? 154 PRO B O   1 
ATOM 3906  C CB  . PRO B 1 154 ? -8.977  -39.157 37.782  1.00 64.16  ? 154 PRO B CB  1 
ATOM 3907  C CG  . PRO B 1 154 ? -9.319  -38.783 36.361  1.00 62.54  ? 154 PRO B CG  1 
ATOM 3908  C CD  . PRO B 1 154 ? -8.820  -37.363 36.225  1.00 63.01  ? 154 PRO B CD  1 
ATOM 3909  N N   . GLY B 1 155 ? -6.948  -37.717 39.528  1.00 69.86  ? 155 GLY B N   1 
ATOM 3910  C CA  . GLY B 1 155 ? -5.991  -37.824 40.641  1.00 62.02  ? 155 GLY B CA  1 
ATOM 3911  C C   . GLY B 1 155 ? -5.136  -36.582 40.790  1.00 62.11  ? 155 GLY B C   1 
ATOM 3912  O O   . GLY B 1 155 ? -3.977  -36.728 41.232  1.00 65.85  ? 155 GLY B O   1 
ATOM 3913  N N   . GLU B 1 156 ? -5.645  -35.411 40.409  1.00 65.44  ? 156 GLU B N   1 
ATOM 3914  C CA  . GLU B 1 156 ? -4.778  -34.204 40.408  1.00 72.26  ? 156 GLU B CA  1 
ATOM 3915  C C   . GLU B 1 156 ? -4.869  -33.424 41.723  1.00 75.28  ? 156 GLU B C   1 
ATOM 3916  O O   . GLU B 1 156 ? -4.211  -32.371 41.789  1.00 90.77  ? 156 GLU B O   1 
ATOM 3917  C CB  . GLU B 1 156 ? -4.993  -33.362 39.146  1.00 68.64  ? 156 GLU B CB  1 
ATOM 3918  C CG  . GLU B 1 156 ? -4.380  -33.971 37.896  1.00 72.44  ? 156 GLU B CG  1 
ATOM 3919  C CD  . GLU B 1 156 ? -4.229  -33.021 36.722  1.00 82.31  ? 156 GLU B CD  1 
ATOM 3920  O OE1 . GLU B 1 156 ? -4.853  -31.943 36.750  1.00 83.64  ? 156 GLU B OE1 1 
ATOM 3921  O OE2 . GLU B 1 156 ? -3.477  -33.353 35.782  1.00 87.86  ? 156 GLU B OE2 1 
ATOM 3922  N N   . LYS B 1 157 ? -5.712  -33.844 42.665  1.00 63.74  ? 157 LYS B N   1 
ATOM 3923  C CA  . LYS B 1 157 ? -5.803  -33.209 44.013  1.00 74.73  ? 157 LYS B CA  1 
ATOM 3924  C C   . LYS B 1 157 ? -6.625  -31.928 43.897  1.00 77.41  ? 157 LYS B C   1 
ATOM 3925  O O   . LYS B 1 157 ? -6.418  -31.192 42.935  1.00 80.87  ? 157 LYS B O   1 
ATOM 3926  C CB  . LYS B 1 157 ? -4.442  -32.942 44.661  1.00 82.61  ? 157 LYS B CB  1 
ATOM 3927  C CG  . LYS B 1 157 ? -4.483  -32.273 46.026  1.00 85.60  ? 157 LYS B CG  1 
ATOM 3928  C CD  . LYS B 1 157 ? -5.188  -33.091 47.085  1.00 87.62  ? 157 LYS B CD  1 
ATOM 3929  C CE  . LYS B 1 157 ? -5.083  -32.506 48.477  1.00 94.29  ? 157 LYS B CE  1 
ATOM 3930  N NZ  . LYS B 1 157 ? -5.961  -33.217 49.437  1.00 97.95  ? 157 LYS B NZ  1 
ATOM 3931  N N   . TYR B 1 158 ? -7.431  -31.617 44.902  1.00 79.37  ? 158 TYR B N   1 
ATOM 3932  C CA  . TYR B 1 158 ? -8.177  -30.341 44.847  1.00 69.61  ? 158 TYR B CA  1 
ATOM 3933  C C   . TYR B 1 158 ? -7.162  -29.209 44.913  1.00 68.24  ? 158 TYR B C   1 
ATOM 3934  O O   . TYR B 1 158 ? -6.205  -29.309 45.682  1.00 61.54  ? 158 TYR B O   1 
ATOM 3935  C CB  . TYR B 1 158 ? -9.258  -30.284 45.925  1.00 63.84  ? 158 TYR B CB  1 
ATOM 3936  C CG  . TYR B 1 158 ? -10.345 -29.274 45.688  1.00 57.55  ? 158 TYR B CG  1 
ATOM 3937  C CD1 . TYR B 1 158 ? -11.276 -29.451 44.678  1.00 58.85  ? 158 TYR B CD1 1 
ATOM 3938  C CD2 . TYR B 1 158 ? -10.450 -28.145 46.477  1.00 57.17  ? 158 TYR B CD2 1 
ATOM 3939  C CE1 . TYR B 1 158 ? -12.276 -28.524 44.450  1.00 57.17  ? 158 TYR B CE1 1 
ATOM 3940  C CE2 . TYR B 1 158 ? -11.449 -27.214 46.269  1.00 58.70  ? 158 TYR B CE2 1 
ATOM 3941  C CZ  . TYR B 1 158 ? -12.363 -27.401 45.250  1.00 53.49  ? 158 TYR B CZ  1 
ATOM 3942  O OH  . TYR B 1 158 ? -13.345 -26.480 45.048  1.00 57.12  ? 158 TYR B OH  1 
ATOM 3943  N N   . PRO B 1 159 ? -7.372  -28.110 44.170  1.00 67.38  ? 159 PRO B N   1 
ATOM 3944  C CA  . PRO B 1 159 ? -6.413  -27.019 44.116  1.00 57.64  ? 159 PRO B CA  1 
ATOM 3945  C C   . PRO B 1 159 ? -6.172  -26.342 45.468  1.00 57.78  ? 159 PRO B C   1 
ATOM 3946  O O   . PRO B 1 159 ? -5.247  -25.570 45.545  1.00 65.16  ? 159 PRO B O   1 
ATOM 3947  C CB  . PRO B 1 159 ? -7.072  -26.067 43.120  1.00 57.95  ? 159 PRO B CB  1 
ATOM 3948  C CG  . PRO B 1 159 ? -7.845  -26.974 42.219  1.00 57.46  ? 159 PRO B CG  1 
ATOM 3949  C CD  . PRO B 1 159 ? -8.455  -27.942 43.201  1.00 62.39  ? 159 PRO B CD  1 
ATOM 3950  N N   . PHE B 1 160 ? -7.024  -26.608 46.465  1.00 59.66  ? 160 PHE B N   1 
ATOM 3951  C CA  . PHE B 1 160 ? -6.885  -25.974 47.804  1.00 61.75  ? 160 PHE B CA  1 
ATOM 3952  C C   . PHE B 1 160 ? -6.980  -26.993 48.954  1.00 63.48  ? 160 PHE B C   1 
ATOM 3953  O O   . PHE B 1 160 ? -8.145  -27.290 49.262  1.00 61.79  ? 160 PHE B O   1 
ATOM 3954  C CB  . PHE B 1 160 ? -8.030  -24.974 47.936  1.00 56.19  ? 160 PHE B CB  1 
ATOM 3955  C CG  . PHE B 1 160 ? -8.364  -24.272 46.641  1.00 56.08  ? 160 PHE B CG  1 
ATOM 3956  C CD1 . PHE B 1 160 ? -7.480  -23.376 46.066  1.00 60.95  ? 160 PHE B CD1 1 
ATOM 3957  C CD2 . PHE B 1 160 ? -9.551  -24.528 45.980  1.00 58.40  ? 160 PHE B CD2 1 
ATOM 3958  C CE1 . PHE B 1 160 ? -7.769  -22.766 44.857  1.00 53.23  ? 160 PHE B CE1 1 
ATOM 3959  C CE2 . PHE B 1 160 ? -9.848  -23.903 44.778  1.00 62.82  ? 160 PHE B CE2 1 
ATOM 3960  C CZ  . PHE B 1 160 ? -8.955  -23.027 44.215  1.00 54.51  ? 160 PHE B CZ  1 
ATOM 3961  N N   . PRO B 1 161 ? -5.904  -27.520 49.637  1.00 68.58  ? 161 PRO B N   1 
ATOM 3962  C CA  . PRO B 1 161 ? -6.142  -28.444 50.754  1.00 73.58  ? 161 PRO B CA  1 
ATOM 3963  C C   . PRO B 1 161 ? -6.994  -27.814 51.867  1.00 68.39  ? 161 PRO B C   1 
ATOM 3964  O O   . PRO B 1 161 ? -7.820  -28.514 52.423  1.00 72.20  ? 161 PRO B O   1 
ATOM 3965  C CB  . PRO B 1 161 ? -4.735  -28.778 51.271  1.00 79.23  ? 161 PRO B CB  1 
ATOM 3966  C CG  . PRO B 1 161 ? -3.876  -27.621 50.806  1.00 73.00  ? 161 PRO B CG  1 
ATOM 3967  C CD  . PRO B 1 161 ? -4.488  -27.173 49.496  1.00 67.23  ? 161 PRO B CD  1 
ATOM 3968  N N   . ASP B 1 162 ? -6.763  -26.534 52.171  1.00 56.47  ? 162 ASP B N   1 
ATOM 3969  C CA  . ASP B 1 162 ? -7.489  -25.848 53.274  1.00 68.10  ? 162 ASP B CA  1 
ATOM 3970  C C   . ASP B 1 162 ? -8.995  -26.105 53.158  1.00 62.35  ? 162 ASP B C   1 
ATOM 3971  O O   . ASP B 1 162 ? -9.615  -26.408 54.197  1.00 69.18  ? 162 ASP B O   1 
ATOM 3972  C CB  . ASP B 1 162 ? -7.183  -24.349 53.283  1.00 63.50  ? 162 ASP B CB  1 
ATOM 3973  C CG  . ASP B 1 162 ? -5.703  -24.035 53.426  1.00 77.61  ? 162 ASP B CG  1 
ATOM 3974  O OD1 . ASP B 1 162 ? -4.928  -24.973 53.701  1.00 85.93  ? 162 ASP B OD1 1 
ATOM 3975  O OD2 . ASP B 1 162 ? -5.337  -22.856 53.257  1.00 74.73  ? 162 ASP B OD2 1 
ATOM 3976  N N   . PHE B 1 163 ? -9.559  -25.992 51.952  1.00 58.70  ? 163 PHE B N   1 
ATOM 3977  C CA  . PHE B 1 163 ? -11.021 -26.144 51.786  1.00 58.05  ? 163 PHE B CA  1 
ATOM 3978  C C   . PHE B 1 163 ? -11.324 -27.633 51.656  1.00 57.20  ? 163 PHE B C   1 
ATOM 3979  O O   . PHE B 1 163 ? -12.142 -28.149 52.427  1.00 65.94  ? 163 PHE B O   1 
ATOM 3980  C CB  . PHE B 1 163 ? -11.500 -25.381 50.552  1.00 58.47  ? 163 PHE B CB  1 
ATOM 3981  C CG  . PHE B 1 163 ? -12.974 -25.510 50.283  1.00 47.69  ? 163 PHE B CG  1 
ATOM 3982  C CD1 . PHE B 1 163 ? -13.889 -24.809 51.047  1.00 52.46  ? 163 PHE B CD1 1 
ATOM 3983  C CD2 . PHE B 1 163 ? -13.444 -26.344 49.283  1.00 44.85  ? 163 PHE B CD2 1 
ATOM 3984  C CE1 . PHE B 1 163 ? -15.246 -24.938 50.814  1.00 51.51  ? 163 PHE B CE1 1 
ATOM 3985  C CE2 . PHE B 1 163 ? -14.801 -26.480 49.059  1.00 52.73  ? 163 PHE B CE2 1 
ATOM 3986  C CZ  . PHE B 1 163 ? -15.699 -25.778 49.826  1.00 53.14  ? 163 PHE B CZ  1 
ATOM 3987  N N   . TYR B 1 164 ? -10.681 -28.301 50.700  1.00 53.43  ? 164 TYR B N   1 
ATOM 3988  C CA  . TYR B 1 164 ? -10.870 -29.765 50.566  1.00 58.79  ? 164 TYR B CA  1 
ATOM 3989  C C   . TYR B 1 164 ? -9.517  -30.458 50.479  1.00 69.67  ? 164 TYR B C   1 
ATOM 3990  O O   . TYR B 1 164 ? -8.746  -30.163 49.559  1.00 72.62  ? 164 TYR B O   1 
ATOM 3991  C CB  . TYR B 1 164 ? -11.711 -30.115 49.340  1.00 57.00  ? 164 TYR B CB  1 
ATOM 3992  C CG  . TYR B 1 164 ? -11.914 -31.590 49.111  1.00 65.64  ? 164 TYR B CG  1 
ATOM 3993  C CD1 . TYR B 1 164 ? -12.441 -32.398 50.100  1.00 64.97  ? 164 TYR B CD1 1 
ATOM 3994  C CD2 . TYR B 1 164 ? -11.580 -32.176 47.904  1.00 66.39  ? 164 TYR B CD2 1 
ATOM 3995  C CE1 . TYR B 1 164 ? -12.626 -33.754 49.901  1.00 54.84  ? 164 TYR B CE1 1 
ATOM 3996  C CE2 . TYR B 1 164 ? -11.762 -33.529 47.684  1.00 68.57  ? 164 TYR B CE2 1 
ATOM 3997  C CZ  . TYR B 1 164 ? -12.285 -34.323 48.687  1.00 61.84  ? 164 TYR B CZ  1 
ATOM 3998  O OH  . TYR B 1 164 ? -12.469 -35.657 48.484  1.00 68.76  ? 164 TYR B OH  1 
ATOM 3999  N N   . ASP B 1 165 ? -9.256  -31.365 51.414  1.00 73.85  ? 165 ASP B N   1 
ATOM 4000  C CA  . ASP B 1 165 ? -7.994  -32.134 51.350  1.00 79.74  ? 165 ASP B CA  1 
ATOM 4001  C C   . ASP B 1 165 ? -8.309  -33.506 50.761  1.00 82.94  ? 165 ASP B C   1 
ATOM 4002  O O   . ASP B 1 165 ? -8.739  -34.391 51.517  1.00 86.73  ? 165 ASP B O   1 
ATOM 4003  C CB  . ASP B 1 165 ? -7.329  -32.229 52.719  1.00 82.69  ? 165 ASP B CB  1 
ATOM 4004  C CG  . ASP B 1 165 ? -5.927  -32.817 52.671  1.00 94.63  ? 165 ASP B CG  1 
ATOM 4005  O OD1 . ASP B 1 165 ? -5.488  -33.195 51.571  1.00 98.71  ? 165 ASP B OD1 1 
ATOM 4006  O OD2 . ASP B 1 165 ? -5.280  -32.880 53.735  1.00 98.56  ? 165 ASP B OD2 1 
ATOM 4007  N N   . ASN B 1 166 ? -8.084  -33.660 49.458  1.00 85.71  ? 166 ASN B N   1 
ATOM 4008  C CA  . ASN B 1 166 ? -8.383  -34.938 48.769  1.00 87.09  ? 166 ASN B CA  1 
ATOM 4009  C C   . ASN B 1 166 ? -7.605  -36.075 49.426  1.00 92.42  ? 166 ASN B C   1 
ATOM 4010  O O   . ASN B 1 166 ? -8.246  -37.076 49.780  1.00 98.69  ? 166 ASN B O   1 
ATOM 4011  C CB  . ASN B 1 166 ? -8.064  -34.838 47.274  1.00 86.21  ? 166 ASN B CB  1 
ATOM 4012  C CG  . ASN B 1 166 ? -8.323  -36.126 46.522  1.00 100.44 ? 166 ASN B CG  1 
ATOM 4013  O OD1 . ASN B 1 166 ? -7.407  -36.722 45.963  1.00 108.08 ? 166 ASN B OD1 1 
ATOM 4014  N ND2 . ASN B 1 166 ? -9.570  -36.567 46.510  1.00 96.14  ? 166 ASN B ND2 1 
ATOM 4015  N N   . SER B 1 167 ? -6.285  -35.919 49.606  1.00 83.79  ? 167 SER B N   1 
ATOM 4016  C CA  . SER B 1 167 ? -5.471  -37.058 50.107  1.00 90.08  ? 167 SER B CA  1 
ATOM 4017  C C   . SER B 1 167 ? -6.298  -37.917 51.068  1.00 100.57 ? 167 SER B C   1 
ATOM 4018  O O   . SER B 1 167 ? -6.121  -39.150 51.024  1.00 105.28 ? 167 SER B O   1 
ATOM 4019  C CB  . SER B 1 167 ? -4.211  -36.571 50.766  1.00 91.66  ? 167 SER B CB  1 
ATOM 4020  O OG  . SER B 1 167 ? -3.345  -37.658 51.054  1.00 87.43  ? 167 SER B OG  1 
ATOM 4021  N N   . ASN B 1 178 ? -22.844 -46.033 42.008  1.00 139.67 ? 178 ASN B N   1 
ATOM 4022  C CA  . ASN B 1 178 ? -21.411 -46.146 41.772  1.00 145.92 ? 178 ASN B CA  1 
ATOM 4023  C C   . ASN B 1 178 ? -21.021 -45.480 40.458  1.00 142.74 ? 178 ASN B C   1 
ATOM 4024  O O   . ASN B 1 178 ? -19.857 -45.144 40.237  1.00 141.31 ? 178 ASN B O   1 
ATOM 4025  C CB  . ASN B 1 178 ? -20.981 -47.612 41.765  1.00 149.31 ? 178 ASN B CB  1 
ATOM 4026  C CG  . ASN B 1 178 ? -21.733 -48.439 40.738  1.00 145.90 ? 178 ASN B CG  1 
ATOM 4027  O OD1 . ASN B 1 178 ? -21.310 -48.560 39.590  1.00 139.59 ? 178 ASN B OD1 1 
ATOM 4028  N ND2 . ASN B 1 178 ? -22.859 -49.011 41.151  1.00 144.56 ? 178 ASN B ND2 1 
ATOM 4029  N N   . MET B 1 179 ? -22.008 -45.287 39.583  1.00 134.95 ? 179 MET B N   1 
ATOM 4030  C CA  . MET B 1 179 ? -21.766 -44.689 38.277  1.00 128.61 ? 179 MET B CA  1 
ATOM 4031  C C   . MET B 1 179 ? -23.006 -43.969 37.767  1.00 121.26 ? 179 MET B C   1 
ATOM 4032  O O   . MET B 1 179 ? -22.906 -42.910 37.135  1.00 116.96 ? 179 MET B O   1 
ATOM 4033  C CB  . MET B 1 179 ? -21.324 -45.766 37.281  1.00 134.42 ? 179 MET B CB  1 
ATOM 4034  C CG  . MET B 1 179 ? -21.397 -45.361 35.809  1.00 145.13 ? 179 MET B CG  1 
ATOM 4035  S SD  . MET B 1 179 ? -20.452 -43.880 35.393  1.00 153.59 ? 179 MET B SD  1 
ATOM 4036  C CE  . MET B 1 179 ? -18.790 -44.390 35.824  1.00 125.49 ? 179 MET B CE  1 
ATOM 4037  N N   . LYS B 1 180 ? -24.180 -44.527 38.052  1.00 119.98 ? 180 LYS B N   1 
ATOM 4038  C CA  . LYS B 1 180 ? -25.422 -44.091 37.419  1.00 108.88 ? 180 LYS B CA  1 
ATOM 4039  C C   . LYS B 1 180 ? -25.893 -42.758 37.996  1.00 98.20  ? 180 LYS B C   1 
ATOM 4040  O O   . LYS B 1 180 ? -26.955 -42.243 37.628  1.00 96.16  ? 180 LYS B O   1 
ATOM 4041  C CB  . LYS B 1 180 ? -26.509 -45.158 37.581  1.00 117.30 ? 180 LYS B CB  1 
ATOM 4042  C CG  . LYS B 1 180 ? -26.077 -46.555 37.198  1.00 120.79 ? 180 LYS B CG  1 
ATOM 4043  C CD  . LYS B 1 180 ? -27.158 -47.570 37.536  1.00 125.37 ? 180 LYS B CD  1 
ATOM 4044  C CE  . LYS B 1 180 ? -26.629 -48.991 37.440  1.00 139.57 ? 180 LYS B CE  1 
ATOM 4045  N NZ  . LYS B 1 180 ? -25.480 -49.228 38.354  1.00 140.60 ? 180 LYS B NZ  1 
ATOM 4046  N N   . LEU B 1 181 ? -25.105 -42.200 38.906  1.00 104.25 ? 181 LEU B N   1 
ATOM 4047  C CA  . LEU B 1 181 ? -25.366 -40.896 39.491  1.00 100.65 ? 181 LEU B CA  1 
ATOM 4048  C C   . LEU B 1 181 ? -24.275 -39.872 39.206  1.00 100.28 ? 181 LEU B C   1 
ATOM 4049  O O   . LEU B 1 181 ? -24.584 -38.683 39.062  1.00 89.59  ? 181 LEU B O   1 
ATOM 4050  C CB  . LEU B 1 181 ? -25.559 -41.033 41.013  1.00 106.30 ? 181 LEU B CB  1 
ATOM 4051  C CG  . LEU B 1 181 ? -26.348 -39.925 41.715  1.00 111.60 ? 181 LEU B CG  1 
ATOM 4052  C CD1 . LEU B 1 181 ? -27.103 -40.490 42.907  1.00 115.89 ? 181 LEU B CD1 1 
ATOM 4053  C CD2 . LEU B 1 181 ? -25.416 -38.813 42.152  1.00 117.61 ? 181 LEU B CD2 1 
ATOM 4054  N N   . LEU B 1 182 ? -23.012 -40.297 39.124  1.00 99.86  ? 182 LEU B N   1 
ATOM 4055  C CA  . LEU B 1 182 ? -21.932 -39.371 38.808  1.00 91.48  ? 182 LEU B CA  1 
ATOM 4056  C C   . LEU B 1 182 ? -22.113 -38.776 37.417  1.00 90.80  ? 182 LEU B C   1 
ATOM 4057  O O   . LEU B 1 182 ? -21.940 -37.566 37.218  1.00 88.03  ? 182 LEU B O   1 
ATOM 4058  C CB  . LEU B 1 182 ? -20.585 -40.088 38.921  1.00 91.72  ? 182 LEU B CB  1 
ATOM 4059  C CG  . LEU B 1 182 ? -19.306 -39.383 38.465  1.00 90.44  ? 182 LEU B CG  1 
ATOM 4060  C CD1 . LEU B 1 182 ? -18.976 -38.183 39.346  1.00 90.05  ? 182 LEU B CD1 1 
ATOM 4061  C CD2 . LEU B 1 182 ? -18.149 -40.371 38.458  1.00 92.89  ? 182 LEU B CD2 1 
ATOM 4062  N N   . HIS B 1 183 ? -22.468 -39.616 36.442  1.00 92.67  ? 183 HIS B N   1 
ATOM 4063  C CA  . HIS B 1 183 ? -22.727 -39.119 35.097  1.00 87.62  ? 183 HIS B CA  1 
ATOM 4064  C C   . HIS B 1 183 ? -23.912 -38.162 35.081  1.00 75.11  ? 183 HIS B C   1 
ATOM 4065  O O   . HIS B 1 183 ? -23.902 -37.164 34.354  1.00 66.78  ? 183 HIS B O   1 
ATOM 4066  C CB  . HIS B 1 183 ? -22.971 -40.283 34.141  1.00 86.91  ? 183 HIS B CB  1 
ATOM 4067  C CG  . HIS B 1 183 ? -23.390 -39.851 32.770  1.00 94.13  ? 183 HIS B CG  1 
ATOM 4068  N ND1 . HIS B 1 183 ? -22.815 -38.783 32.121  1.00 88.92  ? 183 HIS B ND1 1 
ATOM 4069  C CD2 . HIS B 1 183 ? -24.336 -40.339 31.931  1.00 85.81  ? 183 HIS B CD2 1 
ATOM 4070  C CE1 . HIS B 1 183 ? -23.380 -38.633 30.937  1.00 80.50  ? 183 HIS B CE1 1 
ATOM 4071  N NE2 . HIS B 1 183 ? -24.308 -39.563 30.797  1.00 74.79  ? 183 HIS B NE2 1 
ATOM 4072  N N   . ASP B 1 184 ? -24.860 -38.390 35.977  1.00 78.30  ? 184 ASP B N   1 
ATOM 4073  C CA  . ASP B 1 184 ? -26.072 -37.542 35.947  1.00 73.69  ? 184 ASP B CA  1 
ATOM 4074  C C   . ASP B 1 184 ? -25.780 -36.210 36.643  1.00 76.20  ? 184 ASP B C   1 
ATOM 4075  O O   . ASP B 1 184 ? -26.598 -35.303 36.505  1.00 77.85  ? 184 ASP B O   1 
ATOM 4076  C CB  . ASP B 1 184 ? -27.277 -38.308 36.482  1.00 81.43  ? 184 ASP B CB  1 
ATOM 4077  C CG  . ASP B 1 184 ? -27.490 -39.619 35.756  1.00 87.11  ? 184 ASP B CG  1 
ATOM 4078  O OD1 . ASP B 1 184 ? -26.548 -40.428 35.739  1.00 93.20  ? 184 ASP B OD1 1 
ATOM 4079  O OD2 . ASP B 1 184 ? -28.589 -39.815 35.210  1.00 76.21  ? 184 ASP B OD2 1 
ATOM 4080  N N   . PHE B 1 185 ? -24.646 -36.092 37.321  1.00 75.89  ? 185 PHE B N   1 
ATOM 4081  C CA  . PHE B 1 185 ? -24.257 -34.810 37.952  1.00 62.69  ? 185 PHE B CA  1 
ATOM 4082  C C   . PHE B 1 185 ? -23.529 -33.947 36.930  1.00 61.36  ? 185 PHE B C   1 
ATOM 4083  O O   . PHE B 1 185 ? -23.749 -32.745 36.886  1.00 61.26  ? 185 PHE B O   1 
ATOM 4084  C CB  . PHE B 1 185 ? -23.372 -35.110 39.157  1.00 62.33  ? 185 PHE B CB  1 
ATOM 4085  C CG  . PHE B 1 185 ? -22.487 -33.992 39.645  1.00 61.09  ? 185 PHE B CG  1 
ATOM 4086  C CD1 . PHE B 1 185 ? -21.267 -33.732 39.048  1.00 63.11  ? 185 PHE B CD1 1 
ATOM 4087  C CD2 . PHE B 1 185 ? -22.840 -33.242 40.754  1.00 60.78  ? 185 PHE B CD2 1 
ATOM 4088  C CE1 . PHE B 1 185 ? -20.447 -32.722 39.517  1.00 57.19  ? 185 PHE B CE1 1 
ATOM 4089  C CE2 . PHE B 1 185 ? -22.020 -32.229 41.220  1.00 57.78  ? 185 PHE B CE2 1 
ATOM 4090  C CZ  . PHE B 1 185 ? -20.826 -31.970 40.601  1.00 49.11  ? 185 PHE B CZ  1 
ATOM 4091  N N   . ILE B 1 186 ? -22.690 -34.565 36.123  1.00 58.77  ? 186 ILE B N   1 
ATOM 4092  C CA  . ILE B 1 186 ? -21.841 -33.819 35.159  1.00 59.90  ? 186 ILE B CA  1 
ATOM 4093  C C   . ILE B 1 186 ? -22.713 -33.431 33.978  1.00 52.46  ? 186 ILE B C   1 
ATOM 4094  O O   . ILE B 1 186 ? -22.461 -32.398 33.339  1.00 45.12  ? 186 ILE B O   1 
ATOM 4095  C CB  . ILE B 1 186 ? -20.681 -34.737 34.731  1.00 65.54  ? 186 ILE B CB  1 
ATOM 4096  C CG1 . ILE B 1 186 ? -19.899 -35.257 35.938  1.00 63.67  ? 186 ILE B CG1 1 
ATOM 4097  C CG2 . ILE B 1 186 ? -19.777 -34.043 33.728  1.00 61.71  ? 186 ILE B CG2 1 
ATOM 4098  C CD1 . ILE B 1 186 ? -19.640 -36.734 35.878  1.00 69.29  ? 186 ILE B CD1 1 
ATOM 4099  N N   . ALA B 1 187 ? -23.709 -34.260 33.726  1.00 54.97  ? 187 ALA B N   1 
ATOM 4100  C CA  . ALA B 1 187 ? -24.609 -34.008 32.584  1.00 50.71  ? 187 ALA B CA  1 
ATOM 4101  C C   . ALA B 1 187 ? -25.037 -32.552 32.574  1.00 48.04  ? 187 ALA B C   1 
ATOM 4102  O O   . ALA B 1 187 ? -24.824 -31.879 31.572  1.00 52.55  ? 187 ALA B O   1 
ATOM 4103  C CB  . ALA B 1 187 ? -25.803 -34.898 32.717  1.00 62.47  ? 187 ALA B CB  1 
ATOM 4104  N N   . CYS B 1 188 ? -25.631 -32.110 33.669  1.00 46.10  ? 188 CYS B N   1 
ATOM 4105  C CA  . CYS B 1 188 ? -26.154 -30.748 33.624  1.00 42.39  ? 188 CYS B CA  1 
ATOM 4106  C C   . CYS B 1 188 ? -25.058 -29.726 33.361  1.00 39.79  ? 188 CYS B C   1 
ATOM 4107  O O   . CYS B 1 188 ? -25.343 -28.628 32.866  1.00 41.86  ? 188 CYS B O   1 
ATOM 4108  C CB  . CYS B 1 188 ? -26.893 -30.427 34.922  1.00 49.68  ? 188 CYS B CB  1 
ATOM 4109  S SG  . CYS B 1 188 ? -26.146 -31.153 36.391  1.00 81.27  ? 188 CYS B SG  1 
ATOM 4110  N N   . PHE B 1 189 ? -23.806 -30.053 33.687  1.00 40.89  ? 189 PHE B N   1 
ATOM 4111  C CA  . PHE B 1 189 ? -22.704 -29.163 33.338  1.00 37.10  ? 189 PHE B CA  1 
ATOM 4112  C C   . PHE B 1 189 ? -22.284 -29.345 31.886  1.00 39.67  ? 189 PHE B C   1 
ATOM 4113  O O   . PHE B 1 189 ? -21.994 -28.363 31.192  1.00 34.66  ? 189 PHE B O   1 
ATOM 4114  C CB  . PHE B 1 189 ? -21.510 -29.404 34.263  1.00 36.75  ? 189 PHE B CB  1 
ATOM 4115  C CG  . PHE B 1 189 ? -21.789 -29.088 35.701  1.00 46.06  ? 189 PHE B CG  1 
ATOM 4116  C CD1 . PHE B 1 189 ? -21.633 -27.799 36.182  1.00 49.14  ? 189 PHE B CD1 1 
ATOM 4117  C CD2 . PHE B 1 189 ? -22.208 -30.077 36.575  1.00 45.06  ? 189 PHE B CD2 1 
ATOM 4118  C CE1 . PHE B 1 189 ? -21.888 -27.504 37.508  1.00 41.92  ? 189 PHE B CE1 1 
ATOM 4119  C CE2 . PHE B 1 189 ? -22.466 -29.790 37.898  1.00 47.34  ? 189 PHE B CE2 1 
ATOM 4120  C CZ  . PHE B 1 189 ? -22.306 -28.501 38.366  1.00 45.33  ? 189 PHE B CZ  1 
ATOM 4121  N N   . GLU B 1 190 ? -22.250 -30.592 31.412  1.00 39.17  ? 190 GLU B N   1 
ATOM 4122  C CA  . GLU B 1 190 ? -21.828 -30.862 30.041  1.00 43.60  ? 190 GLU B CA  1 
ATOM 4123  C C   . GLU B 1 190 ? -22.861 -30.364 29.035  1.00 48.40  ? 190 GLU B C   1 
ATOM 4124  O O   . GLU B 1 190 ? -22.520 -29.659 28.080  1.00 49.77  ? 190 GLU B O   1 
ATOM 4125  C CB  . GLU B 1 190 ? -21.583 -32.359 29.856  1.00 50.88  ? 190 GLU B CB  1 
ATOM 4126  C CG  . GLU B 1 190 ? -21.367 -32.780 28.412  1.00 69.37  ? 190 GLU B CG  1 
ATOM 4127  C CD  . GLU B 1 190 ? -21.777 -34.221 28.158  1.00 80.44  ? 190 GLU B CD  1 
ATOM 4128  O OE1 . GLU B 1 190 ? -22.320 -34.863 29.082  1.00 70.23  ? 190 GLU B OE1 1 
ATOM 4129  O OE2 . GLU B 1 190 ? -21.560 -34.710 27.028  1.00 80.44  ? 190 GLU B OE2 1 
ATOM 4130  N N   . ARG B 1 191 ? -24.131 -30.724 29.235  1.00 46.43  ? 191 ARG B N   1 
ATOM 4131  C CA  . ARG B 1 191 ? -25.166 -30.383 28.266  1.00 48.77  ? 191 ARG B CA  1 
ATOM 4132  C C   . ARG B 1 191 ? -25.558 -28.913 28.298  1.00 47.12  ? 191 ARG B C   1 
ATOM 4133  O O   . ARG B 1 191 ? -26.369 -28.489 27.465  1.00 51.61  ? 191 ARG B O   1 
ATOM 4134  C CB  . ARG B 1 191 ? -26.404 -31.254 28.492  1.00 52.05  ? 191 ARG B CB  1 
ATOM 4135  C CG  . ARG B 1 191 ? -26.320 -32.608 27.816  1.00 58.44  ? 191 ARG B CG  1 
ATOM 4136  C CD  . ARG B 1 191 ? -26.301 -32.454 26.299  1.00 71.59  ? 191 ARG B CD  1 
ATOM 4137  N NE  . ARG B 1 191 ? -26.028 -33.713 25.617  1.00 84.60  ? 191 ARG B NE  1 
ATOM 4138  C CZ  . ARG B 1 191 ? -26.956 -34.593 25.263  1.00 96.94  ? 191 ARG B CZ  1 
ATOM 4139  N NH1 . ARG B 1 191 ? -28.237 -34.392 25.529  1.00 85.16  ? 191 ARG B NH1 1 
ATOM 4140  N NH2 . ARG B 1 191 ? -26.589 -35.701 24.625  1.00 100.37 ? 191 ARG B NH2 1 
ATOM 4141  N N   . SER B 1 192 ? -25.019 -28.126 29.226  1.00 35.20  ? 192 SER B N   1 
ATOM 4142  C CA  . SER B 1 192 ? -25.334 -26.705 29.266  1.00 42.16  ? 192 SER B CA  1 
ATOM 4143  C C   . SER B 1 192 ? -24.706 -25.998 28.071  1.00 45.74  ? 192 SER B C   1 
ATOM 4144  O O   . SER B 1 192 ? -23.523 -26.190 27.775  1.00 42.73  ? 192 SER B O   1 
ATOM 4145  C CB  . SER B 1 192 ? -24.844 -26.091 30.574  1.00 33.47  ? 192 SER B CB  1 
ATOM 4146  O OG  . SER B 1 192 ? -25.223 -24.729 30.669  1.00 26.37  ? 192 SER B OG  1 
ATOM 4147  N N   . CYS B 1 193 ? -25.499 -25.184 27.381  1.00 44.14  ? 193 CYS B N   1 
ATOM 4148  C CA  . CYS B 1 193 ? -25.048 -24.527 26.159  1.00 41.06  ? 193 CYS B CA  1 
ATOM 4149  C C   . CYS B 1 193 ? -24.215 -23.301 26.520  1.00 48.27  ? 193 CYS B C   1 
ATOM 4150  O O   . CYS B 1 193 ? -24.732 -22.337 27.096  1.00 43.84  ? 193 CYS B O   1 
ATOM 4151  C CB  . CYS B 1 193 ? -26.242 -24.146 25.286  1.00 40.77  ? 193 CYS B CB  1 
ATOM 4152  S SG  . CYS B 1 193 ? -25.812 -23.490 23.656  1.00 58.46  ? 193 CYS B SG  1 
ATOM 4153  N N   . ASP B 1 194 ? -22.919 -23.354 26.198  1.00 52.25  ? 194 ASP B N   1 
ATOM 4154  C CA  . ASP B 1 194 ? -21.988 -22.234 26.320  1.00 47.86  ? 194 ASP B CA  1 
ATOM 4155  C C   . ASP B 1 194 ? -21.751 -21.789 27.763  1.00 48.88  ? 194 ASP B C   1 
ATOM 4156  O O   . ASP B 1 194 ? -20.608 -21.809 28.234  1.00 48.39  ? 194 ASP B O   1 
ATOM 4157  C CB  . ASP B 1 194 ? -22.469 -21.047 25.485  1.00 42.00  ? 194 ASP B CB  1 
ATOM 4158  C CG  . ASP B 1 194 ? -22.544 -21.371 24.008  1.00 58.40  ? 194 ASP B CG  1 
ATOM 4159  O OD1 . ASP B 1 194 ? -21.672 -22.114 23.515  1.00 67.41  ? 194 ASP B OD1 1 
ATOM 4160  O OD2 . ASP B 1 194 ? -23.479 -20.880 23.341  1.00 66.46  ? 194 ASP B OD2 1 
ATOM 4161  N N   . ILE B 1 195 ? -22.800 -21.371 28.469  1.00 42.36  ? 195 ILE B N   1 
ATOM 4162  C CA  . ILE B 1 195 ? -22.658 -20.786 29.793  1.00 34.92  ? 195 ILE B CA  1 
ATOM 4163  C C   . ILE B 1 195 ? -23.372 -21.657 30.817  1.00 25.69  ? 195 ILE B C   1 
ATOM 4164  O O   . ILE B 1 195 ? -24.065 -22.615 30.484  1.00 36.43  ? 195 ILE B O   1 
ATOM 4165  C CB  . ILE B 1 195 ? -23.184 -19.337 29.853  1.00 32.60  ? 195 ILE B CB  1 
ATOM 4166  C CG1 . ILE B 1 195 ? -24.712 -19.319 29.773  1.00 34.16  ? 195 ILE B CG1 1 
ATOM 4167  C CG2 . ILE B 1 195 ? -22.569 -18.494 28.744  1.00 35.60  ? 195 ILE B CG2 1 
ATOM 4168  C CD1 . ILE B 1 195 ? -25.324 -17.958 30.038  1.00 35.29  ? 195 ILE B CD1 1 
ATOM 4169  N N   . ILE B 1 196 ? -23.173 -21.308 32.089  1.00 31.27  ? 196 ILE B N   1 
ATOM 4170  C CA  . ILE B 1 196 ? -23.881 -21.913 33.212  1.00 32.17  ? 196 ILE B CA  1 
ATOM 4171  C C   . ILE B 1 196 ? -24.205 -20.803 34.201  1.00 35.71  ? 196 ILE B C   1 
ATOM 4172  O O   . ILE B 1 196 ? -23.293 -20.172 34.746  1.00 40.43  ? 196 ILE B O   1 
ATOM 4173  C CB  . ILE B 1 196 ? -23.069 -23.018 33.909  1.00 32.07  ? 196 ILE B CB  1 
ATOM 4174  C CG1 . ILE B 1 196 ? -22.910 -24.231 32.995  1.00 30.92  ? 196 ILE B CG1 1 
ATOM 4175  C CG2 . ILE B 1 196 ? -23.739 -23.418 35.214  1.00 35.40  ? 196 ILE B CG2 1 
ATOM 4176  C CD1 . ILE B 1 196 ? -22.234 -25.405 33.658  1.00 28.36  ? 196 ILE B CD1 1 
ATOM 4177  N N   . LEU B 1 197 ? -25.490 -20.555 34.426  1.00 37.56  ? 197 LEU B N   1 
ATOM 4178  C CA  . LEU B 1 197 ? -25.909 -19.566 35.405  1.00 36.29  ? 197 LEU B CA  1 
ATOM 4179  C C   . LEU B 1 197 ? -25.772 -20.131 36.813  1.00 38.72  ? 197 LEU B C   1 
ATOM 4180  O O   . LEU B 1 197 ? -26.064 -21.305 37.056  1.00 34.71  ? 197 LEU B O   1 
ATOM 4181  C CB  . LEU B 1 197 ? -27.355 -19.139 35.148  1.00 36.14  ? 197 LEU B CB  1 
ATOM 4182  C CG  . LEU B 1 197 ? -27.626 -18.369 33.854  1.00 34.35  ? 197 LEU B CG  1 
ATOM 4183  C CD1 . LEU B 1 197 ? -29.114 -18.120 33.687  1.00 36.30  ? 197 LEU B CD1 1 
ATOM 4184  C CD2 . LEU B 1 197 ? -26.863 -17.059 33.862  1.00 43.40  ? 197 LEU B CD2 1 
ATOM 4185  N N   . ILE B 1 198 ? -25.323 -19.293 37.743  1.00 39.69  ? 198 ILE B N   1 
ATOM 4186  C CA  . ILE B 1 198 ? -25.109 -19.728 39.118  1.00 39.03  ? 198 ILE B CA  1 
ATOM 4187  C C   . ILE B 1 198 ? -25.632 -18.667 40.077  1.00 39.38  ? 198 ILE B C   1 
ATOM 4188  O O   . ILE B 1 198 ? -25.412 -17.469 39.880  1.00 38.66  ? 198 ILE B O   1 
ATOM 4189  C CB  . ILE B 1 198 ? -23.622 -20.043 39.396  1.00 42.23  ? 198 ILE B CB  1 
ATOM 4190  C CG1 . ILE B 1 198 ? -23.421 -20.429 40.865  1.00 42.02  ? 198 ILE B CG1 1 
ATOM 4191  C CG2 . ILE B 1 198 ? -22.734 -18.877 39.000  1.00 38.07  ? 198 ILE B CG2 1 
ATOM 4192  C CD1 . ILE B 1 198 ? -21.986 -20.744 41.229  1.00 38.47  ? 198 ILE B CD1 1 
ATOM 4193  N N   . LYS B 1 199 ? -26.346 -19.119 41.110  1.00 49.44  ? 199 LYS B N   1 
ATOM 4194  C CA  . LYS B 1 199 ? -26.803 -18.261 42.204  1.00 45.93  ? 199 LYS B CA  1 
ATOM 4195  C C   . LYS B 1 199 ? -25.643 -18.076 43.174  1.00 43.18  ? 199 LYS B C   1 
ATOM 4196  O O   . LYS B 1 199 ? -25.544 -18.720 44.224  1.00 41.57  ? 199 LYS B O   1 
ATOM 4197  C CB  . LYS B 1 199 ? -28.023 -18.859 42.894  1.00 41.18  ? 199 LYS B CB  1 
ATOM 4198  C CG  . LYS B 1 199 ? -28.573 -18.014 44.031  1.00 41.17  ? 199 LYS B CG  1 
ATOM 4199  C CD  . LYS B 1 199 ? -29.632 -18.770 44.818  1.00 50.74  ? 199 LYS B CD  1 
ATOM 4200  C CE  . LYS B 1 199 ? -30.089 -17.984 46.037  1.00 47.86  ? 199 LYS B CE  1 
ATOM 4201  N NZ  . LYS B 1 199 ? -31.040 -18.773 46.862  1.00 43.29  ? 199 LYS B NZ  1 
ATOM 4202  N N   . SER B 1 200 ? -24.738 -17.180 42.803  1.00 37.28  ? 200 SER B N   1 
ATOM 4203  C CA  . SER B 1 200 ? -23.573 -16.875 43.622  1.00 45.21  ? 200 SER B CA  1 
ATOM 4204  C C   . SER B 1 200 ? -23.025 -15.532 43.164  1.00 41.24  ? 200 SER B C   1 
ATOM 4205  O O   . SER B 1 200 ? -23.540 -14.916 42.228  1.00 45.98  ? 200 SER B O   1 
ATOM 4206  C CB  . SER B 1 200 ? -22.524 -17.988 43.523  1.00 42.85  ? 200 SER B CB  1 
ATOM 4207  O OG  . SER B 1 200 ? -21.435 -17.746 44.399  1.00 38.74  ? 200 SER B OG  1 
ATOM 4208  N N   . PHE B 1 201 ? -21.977 -15.074 43.839  1.00 33.02  ? 201 PHE B N   1 
ATOM 4209  C CA  . PHE B 1 201 ? -21.363 -13.795 43.523  1.00 47.61  ? 201 PHE B CA  1 
ATOM 4210  C C   . PHE B 1 201 ? -19.860 -13.904 43.715  1.00 51.31  ? 201 PHE B C   1 
ATOM 4211  O O   . PHE B 1 201 ? -19.379 -14.658 44.566  1.00 48.83  ? 201 PHE B O   1 
ATOM 4212  C CB  . PHE B 1 201 ? -21.941 -12.654 44.377  1.00 50.96  ? 201 PHE B CB  1 
ATOM 4213  C CG  . PHE B 1 201 ? -22.375 -13.074 45.757  1.00 50.03  ? 201 PHE B CG  1 
ATOM 4214  C CD1 . PHE B 1 201 ? -23.629 -13.629 45.963  1.00 51.15  ? 201 PHE B CD1 1 
ATOM 4215  C CD2 . PHE B 1 201 ? -21.542 -12.892 46.844  1.00 55.52  ? 201 PHE B CD2 1 
ATOM 4216  C CE1 . PHE B 1 201 ? -24.033 -14.014 47.229  1.00 50.91  ? 201 PHE B CE1 1 
ATOM 4217  C CE2 . PHE B 1 201 ? -21.945 -13.269 48.114  1.00 55.14  ? 201 PHE B CE2 1 
ATOM 4218  C CZ  . PHE B 1 201 ? -23.190 -13.834 48.303  1.00 52.25  ? 201 PHE B CZ  1 
ATOM 4219  N N   . ARG B 1 202 ? -19.120 -13.142 42.905  1.00 47.10  ? 202 ARG B N   1 
ATOM 4220  C CA  . ARG B 1 202 ? -17.667 -13.260 42.887  1.00 46.63  ? 202 ARG B CA  1 
ATOM 4221  C C   . ARG B 1 202 ? -17.052 -12.875 44.226  1.00 62.66  ? 202 ARG B C   1 
ATOM 4222  O O   . ARG B 1 202 ? -16.037 -13.456 44.627  1.00 58.21  ? 202 ARG B O   1 
ATOM 4223  C CB  . ARG B 1 202 ? -17.091 -12.403 41.760  1.00 47.50  ? 202 ARG B CB  1 
ATOM 4224  C CG  . ARG B 1 202 ? -15.697 -12.800 41.308  1.00 53.71  ? 202 ARG B CG  1 
ATOM 4225  C CD  . ARG B 1 202 ? -15.593 -12.760 39.792  1.00 49.73  ? 202 ARG B CD  1 
ATOM 4226  N NE  . ARG B 1 202 ? -16.414 -13.788 39.164  1.00 58.86  ? 202 ARG B NE  1 
ATOM 4227  C CZ  . ARG B 1 202 ? -16.716 -13.823 37.870  1.00 69.73  ? 202 ARG B CZ  1 
ATOM 4228  N NH1 . ARG B 1 202 ? -16.297 -12.882 37.038  1.00 83.22  ? 202 ARG B NH1 1 
ATOM 4229  N NH2 . ARG B 1 202 ? -17.457 -14.823 37.404  1.00 46.78  ? 202 ARG B NH2 1 
ATOM 4230  N N   . GLU B 1 203 ? -17.660 -11.926 44.942  1.00 61.97  ? 203 GLU B N   1 
ATOM 4231  C CA  . GLU B 1 203 ? -17.092 -11.446 46.197  1.00 49.06  ? 203 GLU B CA  1 
ATOM 4232  C C   . GLU B 1 203 ? -16.994 -12.535 47.257  1.00 56.26  ? 203 GLU B C   1 
ATOM 4233  O O   . GLU B 1 203 ? -16.251 -12.369 48.228  1.00 64.05  ? 203 GLU B O   1 
ATOM 4234  C CB  . GLU B 1 203 ? -17.929 -10.286 46.735  1.00 60.85  ? 203 GLU B CB  1 
ATOM 4235  C CG  . GLU B 1 203 ? -18.342 -9.286  45.674  1.00 70.54  ? 203 GLU B CG  1 
ATOM 4236  C CD  . GLU B 1 203 ? -17.150 -8.610  45.022  1.00 85.44  ? 203 GLU B CD  1 
ATOM 4237  O OE1 . GLU B 1 203 ? -16.170 -8.311  45.738  1.00 90.78  ? 203 GLU B OE1 1 
ATOM 4238  O OE2 . GLU B 1 203 ? -17.196 -8.383  43.794  1.00 77.98  ? 203 GLU B OE2 1 
ATOM 4239  N N   . LEU B 1 204 ? -17.726 -13.637 47.102  1.00 56.39  ? 204 LEU B N   1 
ATOM 4240  C CA  . LEU B 1 204 ? -17.707 -14.717 48.083  1.00 52.78  ? 204 LEU B CA  1 
ATOM 4241  C C   . LEU B 1 204 ? -16.883 -15.918 47.643  1.00 59.02  ? 204 LEU B C   1 
ATOM 4242  O O   . LEU B 1 204 ? -16.243 -16.557 48.485  1.00 61.59  ? 204 LEU B O   1 
ATOM 4243  C CB  . LEU B 1 204 ? -19.135 -15.174 48.397  1.00 52.35  ? 204 LEU B CB  1 
ATOM 4244  C CG  . LEU B 1 204 ? -19.319 -16.294 49.423  1.00 57.49  ? 204 LEU B CG  1 
ATOM 4245  C CD1 . LEU B 1 204 ? -18.599 -15.976 50.725  1.00 59.17  ? 204 LEU B CD1 1 
ATOM 4246  C CD2 . LEU B 1 204 ? -20.802 -16.545 49.680  1.00 55.90  ? 204 LEU B CD2 1 
ATOM 4247  N N   . GLU B 1 205 ? -16.869 -16.239 46.354  1.00 54.75  ? 205 GLU B N   1 
ATOM 4248  C CA  . GLU B 1 205 ? -16.188 -17.438 45.881  1.00 50.24  ? 205 GLU B CA  1 
ATOM 4249  C C   . GLU B 1 205 ? -15.788 -17.275 44.418  1.00 46.30  ? 205 GLU B C   1 
ATOM 4250  O O   . GLU B 1 205 ? -16.038 -18.145 43.584  1.00 45.36  ? 205 GLU B O   1 
ATOM 4251  C CB  . GLU B 1 205 ? -17.064 -18.675 46.080  1.00 47.02  ? 205 GLU B CB  1 
ATOM 4252  C CG  . GLU B 1 205 ? -18.475 -18.542 45.509  1.00 45.51  ? 205 GLU B CG  1 
ATOM 4253  C CD  . GLU B 1 205 ? -19.184 -19.878 45.351  1.00 48.86  ? 205 GLU B CD  1 
ATOM 4254  O OE1 . GLU B 1 205 ? -18.528 -20.930 45.495  1.00 49.92  ? 205 GLU B OE1 1 
ATOM 4255  O OE2 . GLU B 1 205 ? -20.405 -19.875 45.076  1.00 41.68  ? 205 GLU B OE2 1 
ATOM 4256  N N   . GLY B 1 206 ? -15.156 -16.148 44.082  1.00 49.00  ? 206 GLY B N   1 
ATOM 4257  C CA  . GLY B 1 206 ? -14.691 -15.964 42.717  1.00 45.63  ? 206 GLY B CA  1 
ATOM 4258  C C   . GLY B 1 206 ? -13.656 -16.998 42.320  1.00 45.37  ? 206 GLY B C   1 
ATOM 4259  O O   . GLY B 1 206 ? -13.633 -17.460 41.174  1.00 41.51  ? 206 GLY B O   1 
ATOM 4260  N N   . LYS B 1 207 ? -12.799 -17.383 43.266  1.00 42.97  ? 207 LYS B N   1 
ATOM 4261  C CA  . LYS B 1 207 ? -11.809 -18.425 43.010  1.00 47.01  ? 207 LYS B CA  1 
ATOM 4262  C C   . LYS B 1 207 ? -12.482 -19.733 42.605  1.00 46.29  ? 207 LYS B C   1 
ATOM 4263  O O   . LYS B 1 207 ? -12.134 -20.336 41.579  1.00 45.81  ? 207 LYS B O   1 
ATOM 4264  C CB  . LYS B 1 207 ? -10.941 -18.617 44.256  1.00 47.48  ? 207 LYS B CB  1 
ATOM 4265  C CG  . LYS B 1 207 ? -10.070 -19.856 44.252  1.00 58.08  ? 207 LYS B CG  1 
ATOM 4266  C CD  . LYS B 1 207 ? -9.187  -19.896 45.496  1.00 55.76  ? 207 LYS B CD  1 
ATOM 4267  C CE  . LYS B 1 207 ? -10.013 -19.757 46.770  1.00 55.96  ? 207 LYS B CE  1 
ATOM 4268  N NZ  . LYS B 1 207 ? -9.155  -19.680 47.988  1.00 47.90  ? 207 LYS B NZ  1 
ATOM 4269  N N   . TYR B 1 208 ? -13.465 -20.176 43.387  1.00 47.82  ? 208 TYR B N   1 
ATOM 4270  C CA  . TYR B 1 208 ? -14.137 -21.433 43.080  1.00 43.91  ? 208 TYR B CA  1 
ATOM 4271  C C   . TYR B 1 208 ? -15.010 -21.315 41.838  1.00 39.02  ? 208 TYR B C   1 
ATOM 4272  O O   . TYR B 1 208 ? -15.191 -22.303 41.119  1.00 40.75  ? 208 TYR B O   1 
ATOM 4273  C CB  . TYR B 1 208 ? -14.956 -21.889 44.286  1.00 47.61  ? 208 TYR B CB  1 
ATOM 4274  C CG  . TYR B 1 208 ? -14.131 -22.001 45.549  1.00 40.41  ? 208 TYR B CG  1 
ATOM 4275  C CD1 . TYR B 1 208 ? -13.397 -23.148 45.821  1.00 41.40  ? 208 TYR B CD1 1 
ATOM 4276  C CD2 . TYR B 1 208 ? -14.078 -20.958 46.461  1.00 36.12  ? 208 TYR B CD2 1 
ATOM 4277  C CE1 . TYR B 1 208 ? -12.640 -23.254 46.970  1.00 45.80  ? 208 TYR B CE1 1 
ATOM 4278  C CE2 . TYR B 1 208 ? -13.322 -21.051 47.611  1.00 43.99  ? 208 TYR B CE2 1 
ATOM 4279  C CZ  . TYR B 1 208 ? -12.603 -22.201 47.862  1.00 51.36  ? 208 TYR B CZ  1 
ATOM 4280  O OH  . TYR B 1 208 ? -11.846 -22.302 49.009  1.00 61.94  ? 208 TYR B OH  1 
ATOM 4281  N N   . ILE B 1 209 ? -15.539 -20.125 41.552  1.00 38.59  ? 209 ILE B N   1 
ATOM 4282  C CA  . ILE B 1 209 ? -16.319 -19.945 40.331  1.00 40.14  ? 209 ILE B CA  1 
ATOM 4283  C C   . ILE B 1 209 ? -15.422 -20.072 39.106  1.00 40.65  ? 209 ILE B C   1 
ATOM 4284  O O   . ILE B 1 209 ? -15.791 -20.710 38.113  1.00 27.13  ? 209 ILE B O   1 
ATOM 4285  C CB  . ILE B 1 209 ? -17.063 -18.598 40.360  1.00 43.83  ? 209 ILE B CB  1 
ATOM 4286  C CG1 . ILE B 1 209 ? -18.259 -18.674 41.308  1.00 37.31  ? 209 ILE B CG1 1 
ATOM 4287  C CG2 . ILE B 1 209 ? -17.526 -18.203 38.967  1.00 44.59  ? 209 ILE B CG2 1 
ATOM 4288  C CD1 . ILE B 1 209 ? -19.046 -17.388 41.401  1.00 40.78  ? 209 ILE B CD1 1 
ATOM 4289  N N   . ASP B 1 210 ? -14.230 -19.477 39.154  1.00 50.92  ? 210 ASP B N   1 
ATOM 4290  C CA  . ASP B 1 210 ? -13.279 -19.643 38.059  1.00 55.66  ? 210 ASP B CA  1 
ATOM 4291  C C   . ASP B 1 210 ? -12.840 -21.098 37.926  1.00 53.15  ? 210 ASP B C   1 
ATOM 4292  O O   . ASP B 1 210 ? -12.697 -21.612 36.806  1.00 52.12  ? 210 ASP B O   1 
ATOM 4293  C CB  . ASP B 1 210 ? -12.073 -18.729 38.273  1.00 59.11  ? 210 ASP B CB  1 
ATOM 4294  C CG  . ASP B 1 210 ? -12.451 -17.258 38.262  1.00 67.44  ? 210 ASP B CG  1 
ATOM 4295  O OD1 . ASP B 1 210 ? -13.391 -16.897 37.519  1.00 46.61  ? 210 ASP B OD1 1 
ATOM 4296  O OD2 . ASP B 1 210 ? -11.816 -16.466 38.993  1.00 71.65  ? 210 ASP B OD2 1 
ATOM 4297  N N   . LEU B 1 211 ? -12.617 -21.774 39.058  1.00 41.54  ? 211 LEU B N   1 
ATOM 4298  C CA  . LEU B 1 211 ? -12.289 -23.195 39.004  1.00 43.73  ? 211 LEU B CA  1 
ATOM 4299  C C   . LEU B 1 211 ? -13.391 -23.986 38.311  1.00 49.90  ? 211 LEU B C   1 
ATOM 4300  O O   . LEU B 1 211 ? -13.113 -24.826 37.448  1.00 41.12  ? 211 LEU B O   1 
ATOM 4301  C CB  . LEU B 1 211 ? -12.044 -23.738 40.410  1.00 42.49  ? 211 LEU B CB  1 
ATOM 4302  C CG  . LEU B 1 211 ? -11.777 -25.241 40.515  1.00 45.45  ? 211 LEU B CG  1 
ATOM 4303  C CD1 . LEU B 1 211 ? -10.561 -25.636 39.694  1.00 50.63  ? 211 LEU B CD1 1 
ATOM 4304  C CD2 . LEU B 1 211 ? -11.605 -25.650 41.967  1.00 57.11  ? 211 LEU B CD2 1 
ATOM 4305  N N   . LEU B 1 212 ? -14.649 -23.721 38.675  1.00 50.41  ? 212 LEU B N   1 
ATOM 4306  C CA  . LEU B 1 212 ? -15.777 -24.415 38.059  1.00 45.35  ? 212 LEU B CA  1 
ATOM 4307  C C   . LEU B 1 212 ? -15.878 -24.098 36.573  1.00 43.98  ? 212 LEU B C   1 
ATOM 4308  O O   . LEU B 1 212 ? -16.214 -24.971 35.763  1.00 41.84  ? 212 LEU B O   1 
ATOM 4309  C CB  . LEU B 1 212 ? -17.068 -24.033 38.778  1.00 47.34  ? 212 LEU B CB  1 
ATOM 4310  C CG  . LEU B 1 212 ? -18.305 -24.906 38.564  1.00 48.85  ? 212 LEU B CG  1 
ATOM 4311  C CD1 . LEU B 1 212 ? -18.092 -26.273 39.188  1.00 47.29  ? 212 LEU B CD1 1 
ATOM 4312  C CD2 . LEU B 1 212 ? -19.543 -24.235 39.143  1.00 49.18  ? 212 LEU B CD2 1 
ATOM 4313  N N   . SER B 1 213 ? -15.600 -22.845 36.200  1.00 49.13  ? 213 SER B N   1 
ATOM 4314  C CA  . SER B 1 213 ? -15.562 -22.462 34.790  1.00 42.95  ? 213 SER B CA  1 
ATOM 4315  C C   . SER B 1 213 ? -14.564 -23.314 34.022  1.00 41.90  ? 213 SER B C   1 
ATOM 4316  O O   . SER B 1 213 ? -14.886 -23.870 32.965  1.00 39.92  ? 213 SER B O   1 
ATOM 4317  C CB  . SER B 1 213 ? -15.200 -20.983 34.648  1.00 38.17  ? 213 SER B CB  1 
ATOM 4318  O OG  . SER B 1 213 ? -16.209 -20.142 35.170  1.00 44.07  ? 213 SER B OG  1 
ATOM 4319  N N   . THR B 1 214 ? -13.338 -23.418 34.532  1.00 40.39  ? 214 THR B N   1 
ATOM 4320  C CA  . THR B 1 214 ? -12.334 -24.191 33.815  1.00 41.97  ? 214 THR B CA  1 
ATOM 4321  C C   . THR B 1 214 ? -12.658 -25.679 33.820  1.00 44.10  ? 214 THR B C   1 
ATOM 4322  O O   . THR B 1 214 ? -12.407 -26.371 32.826  1.00 53.95  ? 214 THR B O   1 
ATOM 4323  C CB  . THR B 1 214 ? -10.944 -23.951 34.403  1.00 43.94  ? 214 THR B CB  1 
ATOM 4324  O OG1 . THR B 1 214 ? -10.900 -24.448 35.746  1.00 58.18  ? 214 THR B OG1 1 
ATOM 4325  C CG2 . THR B 1 214 ? -10.617 -22.467 34.396  1.00 45.10  ? 214 THR B CG2 1 
ATOM 4326  N N   . LEU B 1 215 ? -13.230 -26.189 34.911  1.00 44.58  ? 215 LEU B N   1 
ATOM 4327  C CA  . LEU B 1 215 ? -13.501 -27.619 34.993  1.00 47.40  ? 215 LEU B CA  1 
ATOM 4328  C C   . LEU B 1 215 ? -14.647 -28.023 34.072  1.00 50.95  ? 215 LEU B C   1 
ATOM 4329  O O   . LEU B 1 215 ? -14.617 -29.104 33.477  1.00 60.78  ? 215 LEU B O   1 
ATOM 4330  C CB  . LEU B 1 215 ? -13.806 -28.018 36.439  1.00 47.26  ? 215 LEU B CB  1 
ATOM 4331  C CG  . LEU B 1 215 ? -12.602 -28.066 37.385  1.00 50.00  ? 215 LEU B CG  1 
ATOM 4332  C CD1 . LEU B 1 215 ? -13.055 -28.346 38.802  1.00 50.19  ? 215 LEU B CD1 1 
ATOM 4333  C CD2 . LEU B 1 215 ? -11.590 -29.109 36.923  1.00 55.82  ? 215 LEU B CD2 1 
ATOM 4334  N N   . SER B 1 216 ? -15.662 -27.170 33.934  1.00 46.80  ? 216 SER B N   1 
ATOM 4335  C CA  . SER B 1 216 ? -16.809 -27.497 33.103  1.00 40.89  ? 216 SER B CA  1 
ATOM 4336  C C   . SER B 1 216 ? -16.621 -27.120 31.639  1.00 49.64  ? 216 SER B C   1 
ATOM 4337  O O   . SER B 1 216 ? -17.422 -27.556 30.803  1.00 47.34  ? 216 SER B O   1 
ATOM 4338  C CB  . SER B 1 216 ? -18.066 -26.808 33.641  1.00 40.40  ? 216 SER B CB  1 
ATOM 4339  O OG  . SER B 1 216 ? -17.932 -25.398 33.606  1.00 35.55  ? 216 SER B OG  1 
ATOM 4340  N N   . ASP B 1 217 ? -15.585 -26.345 31.313  1.00 52.67  ? 217 ASP B N   1 
ATOM 4341  C CA  . ASP B 1 217 ? -15.405 -25.733 29.997  1.00 50.20  ? 217 ASP B CA  1 
ATOM 4342  C C   . ASP B 1 217 ? -16.574 -24.831 29.620  1.00 47.60  ? 217 ASP B C   1 
ATOM 4343  O O   . ASP B 1 217 ? -16.837 -24.606 28.435  1.00 59.11  ? 217 ASP B O   1 
ATOM 4344  C CB  . ASP B 1 217 ? -15.176 -26.788 28.904  1.00 64.18  ? 217 ASP B CB  1 
ATOM 4345  C CG  . ASP B 1 217 ? -13.868 -27.535 29.082  1.00 74.48  ? 217 ASP B CG  1 
ATOM 4346  O OD1 . ASP B 1 217 ? -13.187 -27.303 30.103  1.00 81.53  ? 217 ASP B OD1 1 
ATOM 4347  O OD2 . ASP B 1 217 ? -13.520 -28.348 28.197  1.00 74.79  ? 217 ASP B OD2 1 
ATOM 4348  N N   . LYS B 1 218 ? -17.288 -24.307 30.611  1.00 41.96  ? 218 LYS B N   1 
ATOM 4349  C CA  . LYS B 1 218 ? -18.389 -23.385 30.390  1.00 44.44  ? 218 LYS B CA  1 
ATOM 4350  C C   . LYS B 1 218 ? -18.117 -22.085 31.134  1.00 37.88  ? 218 LYS B C   1 
ATOM 4351  O O   . LYS B 1 218 ? -17.392 -22.063 32.131  1.00 37.55  ? 218 LYS B O   1 
ATOM 4352  C CB  . LYS B 1 218 ? -19.730 -23.975 30.854  1.00 37.55  ? 218 LYS B CB  1 
ATOM 4353  C CG  . LYS B 1 218 ? -20.477 -24.776 29.793  1.00 40.00  ? 218 LYS B CG  1 
ATOM 4354  C CD  . LYS B 1 218 ? -19.741 -26.050 29.429  1.00 40.58  ? 218 LYS B CD  1 
ATOM 4355  C CE  . LYS B 1 218 ? -20.565 -26.917 28.506  1.00 36.04  ? 218 LYS B CE  1 
ATOM 4356  N NZ  . LYS B 1 218 ? -20.988 -26.146 27.312  1.00 48.92  ? 218 LYS B NZ  1 
ATOM 4357  N N   . THR B 1 219 ? -18.700 -21.002 30.639  1.00 37.67  ? 219 THR B N   1 
ATOM 4358  C CA  . THR B 1 219 ? -18.551 -19.713 31.295  1.00 40.05  ? 219 THR B CA  1 
ATOM 4359  C C   . THR B 1 219 ? -19.563 -19.622 32.429  1.00 43.57  ? 219 THR B C   1 
ATOM 4360  O O   . THR B 1 219 ? -20.776 -19.664 32.196  1.00 41.04  ? 219 THR B O   1 
ATOM 4361  C CB  . THR B 1 219 ? -18.732 -18.569 30.297  1.00 44.81  ? 219 THR B CB  1 
ATOM 4362  O OG1 . THR B 1 219 ? -17.820 -18.746 29.206  1.00 44.58  ? 219 THR B OG1 1 
ATOM 4363  C CG2 . THR B 1 219 ? -18.443 -17.233 30.967  1.00 42.99  ? 219 THR B CG2 1 
ATOM 4364  N N   . LEU B 1 220 ? -19.068 -19.545 33.659  1.00 47.81  ? 220 LEU B N   1 
ATOM 4365  C CA  . LEU B 1 220 ? -19.937 -19.397 34.815  1.00 38.09  ? 220 LEU B CA  1 
ATOM 4366  C C   . LEU B 1 220 ? -20.415 -17.954 34.887  1.00 41.75  ? 220 LEU B C   1 
ATOM 4367  O O   . LEU B 1 220 ? -19.604 -17.030 35.007  1.00 45.18  ? 220 LEU B O   1 
ATOM 4368  C CB  . LEU B 1 220 ? -19.210 -19.796 36.096  1.00 36.75  ? 220 LEU B CB  1 
ATOM 4369  C CG  . LEU B 1 220 ? -19.449 -21.216 36.611  1.00 37.36  ? 220 LEU B CG  1 
ATOM 4370  C CD1 . LEU B 1 220 ? -20.891 -21.384 37.063  1.00 41.52  ? 220 LEU B CD1 1 
ATOM 4371  C CD2 . LEU B 1 220 ? -19.099 -22.253 35.557  1.00 34.07  ? 220 LEU B CD2 1 
ATOM 4372  N N   . VAL B 1 221 ? -21.723 -17.761 34.795  1.00 38.97  ? 221 VAL B N   1 
ATOM 4373  C CA  . VAL B 1 221 ? -22.324 -16.436 34.865  1.00 41.21  ? 221 VAL B CA  1 
ATOM 4374  C C   . VAL B 1 221 ? -23.038 -16.324 36.210  1.00 40.45  ? 221 VAL B C   1 
ATOM 4375  O O   . VAL B 1 221 ? -24.050 -17.008 36.439  1.00 39.42  ? 221 VAL B O   1 
ATOM 4376  C CB  . VAL B 1 221 ? -23.280 -16.182 33.694  1.00 35.78  ? 221 VAL B CB  1 
ATOM 4377  C CG1 . VAL B 1 221 ? -23.732 -14.739 33.698  1.00 38.46  ? 221 VAL B CG1 1 
ATOM 4378  C CG2 . VAL B 1 221 ? -22.598 -16.522 32.380  1.00 34.80  ? 221 VAL B CG2 1 
ATOM 4379  N N   . PRO B 1 222 ? -22.532 -15.521 37.139  1.00 38.36  ? 222 PRO B N   1 
ATOM 4380  C CA  . PRO B 1 222 ? -23.204 -15.366 38.431  1.00 42.50  ? 222 PRO B CA  1 
ATOM 4381  C C   . PRO B 1 222 ? -24.322 -14.340 38.359  1.00 39.08  ? 222 PRO B C   1 
ATOM 4382  O O   . PRO B 1 222 ? -24.177 -13.267 37.767  1.00 47.50  ? 222 PRO B O   1 
ATOM 4383  C CB  . PRO B 1 222 ? -22.075 -14.895 39.354  1.00 39.28  ? 222 PRO B CB  1 
ATOM 4384  C CG  . PRO B 1 222 ? -21.148 -14.155 38.441  1.00 39.06  ? 222 PRO B CG  1 
ATOM 4385  C CD  . PRO B 1 222 ? -21.215 -14.860 37.111  1.00 35.33  ? 222 PRO B CD  1 
ATOM 4386  N N   . VAL B 1 223 ? -25.452 -14.683 38.969  1.00 37.95  ? 223 VAL B N   1 
ATOM 4387  C CA  . VAL B 1 223 ? -26.604 -13.798 39.042  1.00 41.84  ? 223 VAL B CA  1 
ATOM 4388  C C   . VAL B 1 223 ? -26.763 -13.214 40.443  1.00 50.19  ? 223 VAL B C   1 
ATOM 4389  O O   . VAL B 1 223 ? -27.831 -12.707 40.788  1.00 44.96  ? 223 VAL B O   1 
ATOM 4390  C CB  . VAL B 1 223 ? -27.889 -14.512 38.589  1.00 35.82  ? 223 VAL B CB  1 
ATOM 4391  C CG1 . VAL B 1 223 ? -27.774 -14.938 37.131  1.00 38.10  ? 223 VAL B CG1 1 
ATOM 4392  C CG2 . VAL B 1 223 ? -28.169 -15.704 39.483  1.00 35.85  ? 223 VAL B CG2 1 
ATOM 4393  N N   . GLY B 1 224 ? -25.714 -13.282 41.260  1.00 46.98  ? 224 GLY B N   1 
ATOM 4394  C CA  . GLY B 1 224 ? -25.744 -12.735 42.595  1.00 41.21  ? 224 GLY B CA  1 
ATOM 4395  C C   . GLY B 1 224 ? -26.726 -13.461 43.487  1.00 46.18  ? 224 GLY B C   1 
ATOM 4396  O O   . GLY B 1 224 ? -27.182 -14.567 43.181  1.00 53.06  ? 224 GLY B O   1 
ATOM 4397  N N   . PRO B 1 225 ? -27.060 -12.859 44.621  1.00 37.44  ? 225 PRO B N   1 
ATOM 4398  C CA  . PRO B 1 225 ? -28.101 -13.423 45.479  1.00 42.71  ? 225 PRO B CA  1 
ATOM 4399  C C   . PRO B 1 225 ? -29.484 -13.013 44.996  1.00 65.08  ? 225 PRO B C   1 
ATOM 4400  O O   . PRO B 1 225 ? -29.655 -12.066 44.225  1.00 76.77  ? 225 PRO B O   1 
ATOM 4401  C CB  . PRO B 1 225 ? -27.792 -12.813 46.846  1.00 46.94  ? 225 PRO B CB  1 
ATOM 4402  C CG  . PRO B 1 225 ? -27.249 -11.470 46.503  1.00 44.84  ? 225 PRO B CG  1 
ATOM 4403  C CD  . PRO B 1 225 ? -26.466 -11.646 45.213  1.00 41.06  ? 225 PRO B CD  1 
ATOM 4404  N N   . LEU B 1 226 ? -30.482 -13.751 45.470  1.00 56.49  ? 226 LEU B N   1 
ATOM 4405  C CA  . LEU B 1 226 ? -31.877 -13.504 45.124  1.00 54.78  ? 226 LEU B CA  1 
ATOM 4406  C C   . LEU B 1 226 ? -32.664 -13.391 46.422  1.00 60.72  ? 226 LEU B C   1 
ATOM 4407  O O   . LEU B 1 226 ? -32.891 -14.399 47.098  1.00 65.86  ? 226 LEU B O   1 
ATOM 4408  C CB  . LEU B 1 226 ? -32.422 -14.618 44.232  1.00 60.07  ? 226 LEU B CB  1 
ATOM 4409  C CG  . LEU B 1 226 ? -31.678 -14.795 42.905  1.00 50.33  ? 226 LEU B CG  1 
ATOM 4410  C CD1 . LEU B 1 226 ? -31.599 -16.264 42.517  1.00 47.58  ? 226 LEU B CD1 1 
ATOM 4411  C CD2 . LEU B 1 226 ? -32.354 -13.988 41.803  1.00 58.60  ? 226 LEU B CD2 1 
ATOM 4412  N N   . VAL B 1 227 ? -33.080 -12.166 46.751  1.00 63.23  ? 227 VAL B N   1 
ATOM 4413  C CA  . VAL B 1 227 ? -33.686 -11.798 48.037  1.00 55.68  ? 227 VAL B CA  1 
ATOM 4414  C C   . VAL B 1 227 ? -33.009 -12.510 49.202  1.00 58.32  ? 227 VAL B C   1 
ATOM 4415  O O   . VAL B 1 227 ? -31.809 -12.347 49.419  1.00 55.53  ? 227 VAL B O   1 
ATOM 4416  C CB  . VAL B 1 227 ? -35.218 -12.054 48.049  1.00 68.91  ? 227 VAL B CB  1 
ATOM 4417  C CG1 . VAL B 1 227 ? -35.864 -11.508 46.786  1.00 75.35  ? 227 VAL B CG1 1 
ATOM 4418  C CG2 . VAL B 1 227 ? -35.553 -13.531 48.263  1.00 64.49  ? 227 VAL B CG2 1 
ATOM 4419  N N   . ASP B 1 236 ? -49.506 -14.469 59.262  1.00 149.79 ? 236 ASP B N   1 
ATOM 4420  C CA  . ASP B 1 236 ? -48.882 -13.244 58.769  1.00 153.18 ? 236 ASP B CA  1 
ATOM 4421  C C   . ASP B 1 236 ? -49.141 -12.019 59.661  1.00 150.13 ? 236 ASP B C   1 
ATOM 4422  O O   . ASP B 1 236 ? -48.276 -11.152 59.764  1.00 139.79 ? 236 ASP B O   1 
ATOM 4423  C CB  . ASP B 1 236 ? -49.337 -12.959 57.334  1.00 158.97 ? 236 ASP B CB  1 
ATOM 4424  C CG  . ASP B 1 236 ? -48.774 -13.954 56.341  1.00 164.18 ? 236 ASP B CG  1 
ATOM 4425  O OD1 . ASP B 1 236 ? -47.731 -14.572 56.646  1.00 161.04 ? 236 ASP B OD1 1 
ATOM 4426  O OD2 . ASP B 1 236 ? -49.367 -14.115 55.253  1.00 167.62 ? 236 ASP B OD2 1 
ATOM 4427  N N   . PRO B 1 237 ? -50.314 -11.923 60.297  1.00 151.76 ? 237 PRO B N   1 
ATOM 4428  C CA  . PRO B 1 237 ? -50.458 -10.961 61.403  1.00 154.26 ? 237 PRO B CA  1 
ATOM 4429  C C   . PRO B 1 237 ? -49.684 -11.346 62.655  1.00 153.75 ? 237 PRO B C   1 
ATOM 4430  O O   . PRO B 1 237 ? -49.776 -10.636 63.661  1.00 153.78 ? 237 PRO B O   1 
ATOM 4431  C CB  . PRO B 1 237 ? -51.970 -10.954 61.672  1.00 152.23 ? 237 PRO B CB  1 
ATOM 4432  C CG  . PRO B 1 237 ? -52.578 -11.382 60.394  1.00 148.72 ? 237 PRO B CG  1 
ATOM 4433  C CD  . PRO B 1 237 ? -51.634 -12.403 59.840  1.00 144.88 ? 237 PRO B CD  1 
ATOM 4434  N N   . LYS B 1 238 ? -48.929 -12.442 62.626  1.00 151.06 ? 238 LYS B N   1 
ATOM 4435  C CA  . LYS B 1 238 ? -48.163 -12.909 63.771  1.00 145.89 ? 238 LYS B CA  1 
ATOM 4436  C C   . LYS B 1 238 ? -46.738 -12.367 63.799  1.00 143.28 ? 238 LYS B C   1 
ATOM 4437  O O   . LYS B 1 238 ? -45.983 -12.701 64.720  1.00 145.85 ? 238 LYS B O   1 
ATOM 4438  C CB  . LYS B 1 238 ? -48.121 -14.443 63.783  1.00 139.77 ? 238 LYS B CB  1 
ATOM 4439  C CG  . LYS B 1 238 ? -47.433 -15.047 62.566  1.00 134.97 ? 238 LYS B CG  1 
ATOM 4440  C CD  . LYS B 1 238 ? -47.337 -16.562 62.664  1.00 125.88 ? 238 LYS B CD  1 
ATOM 4441  C CE  . LYS B 1 238 ? -46.539 -17.131 61.498  1.00 123.95 ? 238 LYS B CE  1 
ATOM 4442  N NZ  . LYS B 1 238 ? -46.371 -18.608 61.595  1.00 113.01 ? 238 LYS B NZ  1 
ATOM 4443  N N   . THR B 1 239 ? -46.351 -11.549 62.821  1.00 136.51 ? 239 THR B N   1 
ATOM 4444  C CA  . THR B 1 239 ? -44.988 -11.038 62.735  1.00 132.59 ? 239 THR B CA  1 
ATOM 4445  C C   . THR B 1 239 ? -44.838 -9.621  63.270  1.00 130.73 ? 239 THR B C   1 
ATOM 4446  O O   . THR B 1 239 ? -43.709 -9.126  63.352  1.00 121.60 ? 239 THR B O   1 
ATOM 4447  C CB  . THR B 1 239 ? -44.493 -11.068 61.284  1.00 130.86 ? 239 THR B CB  1 
ATOM 4448  O OG1 . THR B 1 239 ? -43.162 -10.550 61.230  1.00 127.85 ? 239 THR B OG1 1 
ATOM 4449  C CG2 . THR B 1 239 ? -45.383 -10.214 60.404  1.00 134.82 ? 239 THR B CG2 1 
ATOM 4450  N N   . GLU B 1 240 ? -45.940 -8.953  63.621  1.00 140.03 ? 240 GLU B N   1 
ATOM 4451  C CA  . GLU B 1 240 ? -45.845 -7.591  64.135  1.00 138.07 ? 240 GLU B CA  1 
ATOM 4452  C C   . GLU B 1 240 ? -45.105 -7.562  65.469  1.00 128.67 ? 240 GLU B C   1 
ATOM 4453  O O   . GLU B 1 240 ? -44.322 -6.643  65.732  1.00 118.92 ? 240 GLU B O   1 
ATOM 4454  C CB  . GLU B 1 240 ? -47.242 -6.991  64.275  1.00 141.24 ? 240 GLU B CB  1 
ATOM 4455  C CG  . GLU B 1 240 ? -48.244 -7.545  63.266  1.00 141.60 ? 240 GLU B CG  1 
ATOM 4456  C CD  . GLU B 1 240 ? -49.601 -6.866  63.339  1.00 147.59 ? 240 GLU B CD  1 
ATOM 4457  O OE1 . GLU B 1 240 ? -49.669 -5.706  63.795  1.00 142.84 ? 240 GLU B OE1 1 
ATOM 4458  O OE2 . GLU B 1 240 ? -50.603 -7.496  62.939  1.00 157.59 ? 240 GLU B OE2 1 
ATOM 4459  N N   . GLN B 1 241 ? -45.342 -8.567  66.318  1.00 132.37 ? 241 GLN B N   1 
ATOM 4460  C CA  . GLN B 1 241 ? -44.605 -8.671  67.573  1.00 128.80 ? 241 GLN B CA  1 
ATOM 4461  C C   . GLN B 1 241 ? -43.103 -8.750  67.323  1.00 123.63 ? 241 GLN B C   1 
ATOM 4462  O O   . GLN B 1 241 ? -42.315 -8.150  68.063  1.00 122.41 ? 241 GLN B O   1 
ATOM 4463  C CB  . GLN B 1 241 ? -45.082 -9.888  68.367  1.00 133.94 ? 241 GLN B CB  1 
ATOM 4464  C CG  . GLN B 1 241 ? -46.408 -9.701  69.100  1.00 133.06 ? 241 GLN B CG  1 
ATOM 4465  C CD  . GLN B 1 241 ? -47.623 -9.898  68.211  1.00 130.86 ? 241 GLN B CD  1 
ATOM 4466  O OE1 . GLN B 1 241 ? -47.679 -10.827 67.408  1.00 139.01 ? 241 GLN B OE1 1 
ATOM 4467  N NE2 . GLN B 1 241 ? -48.607 -9.020  68.360  1.00 123.89 ? 241 GLN B NE2 1 
ATOM 4468  N N   . ILE B 1 242 ? -42.692 -9.471  66.277  1.00 125.45 ? 242 ILE B N   1 
ATOM 4469  C CA  . ILE B 1 242 ? -41.269 -9.626  65.974  1.00 117.22 ? 242 ILE B CA  1 
ATOM 4470  C C   . ILE B 1 242 ? -40.621 -8.269  65.732  1.00 116.92 ? 242 ILE B C   1 
ATOM 4471  O O   . ILE B 1 242 ? -39.621 -7.914  66.368  1.00 118.26 ? 242 ILE B O   1 
ATOM 4472  C CB  . ILE B 1 242 ? -41.079 -10.558 64.762  1.00 118.90 ? 242 ILE B CB  1 
ATOM 4473  C CG1 . ILE B 1 242 ? -41.732 -11.915 65.021  1.00 122.63 ? 242 ILE B CG1 1 
ATOM 4474  C CG2 . ILE B 1 242 ? -39.601 -10.724 64.443  1.00 106.26 ? 242 ILE B CG2 1 
ATOM 4475  C CD1 . ILE B 1 242 ? -41.092 -12.694 66.144  1.00 109.71 ? 242 ILE B CD1 1 
ATOM 4476  N N   . ILE B 1 243 ? -41.175 -7.489  64.800  1.00 118.50 ? 243 ILE B N   1 
ATOM 4477  C CA  . ILE B 1 243 ? -40.571 -6.203  64.458  1.00 115.51 ? 243 ILE B CA  1 
ATOM 4478  C C   . ILE B 1 243 ? -40.695 -5.224  65.621  1.00 112.72 ? 243 ILE B C   1 
ATOM 4479  O O   . ILE B 1 243 ? -39.781 -4.430  65.877  1.00 107.56 ? 243 ILE B O   1 
ATOM 4480  C CB  . ILE B 1 243 ? -41.198 -5.642  63.169  1.00 119.69 ? 243 ILE B CB  1 
ATOM 4481  C CG1 . ILE B 1 243 ? -40.890 -6.563  61.985  1.00 122.58 ? 243 ILE B CG1 1 
ATOM 4482  C CG2 . ILE B 1 243 ? -40.680 -4.242  62.883  1.00 114.53 ? 243 ILE B CG2 1 
ATOM 4483  C CD1 . ILE B 1 243 ? -39.408 -6.733  61.708  1.00 113.15 ? 243 ILE B CD1 1 
ATOM 4484  N N   . ASN B 1 244 ? -41.816 -5.264  66.347  1.00 114.02 ? 244 ASN B N   1 
ATOM 4485  C CA  . ASN B 1 244 ? -41.967 -4.367  67.489  1.00 115.80 ? 244 ASN B CA  1 
ATOM 4486  C C   . ASN B 1 244 ? -40.929 -4.668  68.563  1.00 116.19 ? 244 ASN B C   1 
ATOM 4487  O O   . ASN B 1 244 ? -40.390 -3.748  69.191  1.00 115.60 ? 244 ASN B O   1 
ATOM 4488  C CB  . ASN B 1 244 ? -43.381 -4.471  68.064  1.00 119.73 ? 244 ASN B CB  1 
ATOM 4489  C CG  . ASN B 1 244 ? -43.639 -3.445  69.151  1.00 121.54 ? 244 ASN B CG  1 
ATOM 4490  O OD1 . ASN B 1 244 ? -42.995 -2.396  69.194  1.00 117.56 ? 244 ASN B OD1 1 
ATOM 4491  N ND2 . ASN B 1 244 ? -44.581 -3.743  70.039  1.00 117.21 ? 244 ASN B ND2 1 
ATOM 4492  N N   . TRP B 1 245 ? -40.465 -5.915  68.636  1.00 110.53 ? 245 TRP B N   1 
ATOM 4493  C CA  . TRP B 1 245 ? -39.419 -6.290  69.626  1.00 106.57 ? 245 TRP B CA  1 
ATOM 4494  C C   . TRP B 1 245 ? -38.035 -5.849  69.157  1.00 99.70  ? 245 TRP B C   1 
ATOM 4495  O O   . TRP B 1 245 ? -37.289 -5.338  69.985  1.00 90.94  ? 245 TRP B O   1 
ATOM 4496  C CB  . TRP B 1 245 ? -39.460 -7.799  69.860  1.00 105.40 ? 245 TRP B CB  1 
ATOM 4497  C CG  . TRP B 1 245 ? -38.545 -8.321  70.924  1.00 101.61 ? 245 TRP B CG  1 
ATOM 4498  C CD1 . TRP B 1 245 ? -38.881 -8.625  72.211  1.00 100.66 ? 245 TRP B CD1 1 
ATOM 4499  C CD2 . TRP B 1 245 ? -37.156 -8.670  70.785  1.00 99.42  ? 245 TRP B CD2 1 
ATOM 4500  N NE1 . TRP B 1 245 ? -37.794 -9.101  72.889  1.00 98.23  ? 245 TRP B NE1 1 
ATOM 4501  C CE2 . TRP B 1 245 ? -36.722 -9.143  72.042  1.00 96.25  ? 245 TRP B CE2 1 
ATOM 4502  C CE3 . TRP B 1 245 ? -36.234 -8.613  69.736  1.00 92.81  ? 245 TRP B CE3 1 
ATOM 4503  C CZ2 . TRP B 1 245 ? -35.413 -9.557  72.270  1.00 96.49  ? 245 TRP B CZ2 1 
ATOM 4504  C CZ3 . TRP B 1 245 ? -34.941 -9.019  69.964  1.00 89.07  ? 245 TRP B CZ3 1 
ATOM 4505  C CH2 . TRP B 1 245 ? -34.538 -9.481  71.215  1.00 95.53  ? 245 TRP B CH2 1 
ATOM 4506  N N   . LEU B 1 246 ? -37.716 -6.046  67.880  1.00 98.20  ? 246 LEU B N   1 
ATOM 4507  C CA  . LEU B 1 246 ? -36.356 -5.766  67.351  1.00 91.78  ? 246 LEU B CA  1 
ATOM 4508  C C   . LEU B 1 246 ? -36.117 -4.266  67.251  1.00 88.33  ? 246 LEU B C   1 
ATOM 4509  O O   . LEU B 1 246 ? -34.961 -3.862  67.336  1.00 86.71  ? 246 LEU B O   1 
ATOM 4510  C CB  . LEU B 1 246 ? -36.243 -6.437  65.980  1.00 92.05  ? 246 LEU B CB  1 
ATOM 4511  C CG  . LEU B 1 246 ? -34.837 -6.756  65.486  1.00 79.02  ? 246 LEU B CG  1 
ATOM 4512  C CD1 . LEU B 1 246 ? -34.145 -7.709  66.439  1.00 82.92  ? 246 LEU B CD1 1 
ATOM 4513  C CD2 . LEU B 1 246 ? -34.898 -7.366  64.099  1.00 78.41  ? 246 LEU B CD2 1 
ATOM 4514  N N   . ASP B 1 247 ? -37.170 -3.489  67.076  1.00 91.05  ? 247 ASP B N   1 
ATOM 4515  C CA  . ASP B 1 247 ? -36.975 -2.038  66.863  1.00 93.77  ? 247 ASP B CA  1 
ATOM 4516  C C   . ASP B 1 247 ? -36.598 -1.372  68.180  1.00 90.49  ? 247 ASP B C   1 
ATOM 4517  O O   . ASP B 1 247 ? -35.908 -0.348  68.133  1.00 83.43  ? 247 ASP B O   1 
ATOM 4518  C CB  . ASP B 1 247 ? -38.215 -1.393  66.252  1.00 92.52  ? 247 ASP B CB  1 
ATOM 4519  C CG  . ASP B 1 247 ? -38.675 -2.040  64.960  1.00 95.55  ? 247 ASP B CG  1 
ATOM 4520  O OD1 . ASP B 1 247 ? -38.070 -3.055  64.576  1.00 96.01  ? 247 ASP B OD1 1 
ATOM 4521  O OD2 . ASP B 1 247 ? -39.624 -1.520  64.347  1.00 97.69  ? 247 ASP B OD2 1 
ATOM 4522  N N   . LYS B 1 248 ? -37.007 -1.957  69.302  1.00 98.31  ? 248 LYS B N   1 
ATOM 4523  C CA  . LYS B 1 248 ? -36.767 -1.324  70.619  1.00 98.21  ? 248 LYS B CA  1 
ATOM 4524  C C   . LYS B 1 248 ? -35.435 -1.790  71.199  1.00 92.68  ? 248 LYS B C   1 
ATOM 4525  O O   . LYS B 1 248 ? -35.247 -1.658  72.414  1.00 89.00  ? 248 LYS B O   1 
ATOM 4526  C CB  . LYS B 1 248 ? -37.945 -1.632  71.539  1.00 102.57 ? 248 LYS B CB  1 
ATOM 4527  C CG  . LYS B 1 248 ? -38.366 -0.485  72.446  1.00 100.19 ? 248 LYS B CG  1 
ATOM 4528  C CD  . LYS B 1 248 ? -38.336 0.856   71.749  1.00 106.73 ? 248 LYS B CD  1 
ATOM 4529  C CE  . LYS B 1 248 ? -39.202 1.899   72.420  1.00 102.81 ? 248 LYS B CE  1 
ATOM 4530  N NZ  . LYS B 1 248 ? -40.639 1.553   72.327  1.00 103.15 ? 248 LYS B NZ  1 
ATOM 4531  N N   . ARG B 1 249 ? -34.544 -2.302  70.352  1.00 94.89  ? 249 ARG B N   1 
ATOM 4532  C CA  . ARG B 1 249 ? -33.208 -2.762  70.792  1.00 88.54  ? 249 ARG B CA  1 
ATOM 4533  C C   . ARG B 1 249 ? -32.182 -1.991  69.989  1.00 86.40  ? 249 ARG B C   1 
ATOM 4534  O O   . ARG B 1 249 ? -32.509 -1.549  68.883  1.00 86.09  ? 249 ARG B O   1 
ATOM 4535  C CB  . ARG B 1 249 ? -33.041 -4.253  70.518  1.00 92.95  ? 249 ARG B CB  1 
ATOM 4536  C CG  . ARG B 1 249 ? -34.329 -5.062  70.564  1.00 90.73  ? 249 ARG B CG  1 
ATOM 4537  C CD  . ARG B 1 249 ? -34.902 -5.275  71.951  1.00 87.56  ? 249 ARG B CD  1 
ATOM 4538  N NE  . ARG B 1 249 ? -34.135 -6.241  72.715  1.00 87.92  ? 249 ARG B NE  1 
ATOM 4539  C CZ  . ARG B 1 249 ? -33.436 -5.945  73.802  1.00 97.97  ? 249 ARG B CZ  1 
ATOM 4540  N NH1 . ARG B 1 249 ? -33.235 -4.683  74.130  1.00 99.27  ? 249 ARG B NH1 1 
ATOM 4541  N NH2 . ARG B 1 249 ? -32.928 -6.907  74.548  1.00 101.07 ? 249 ARG B NH2 1 
ATOM 4542  N N   . ALA B 1 250 ? -30.973 -1.883  70.503  1.00 85.95  ? 250 ALA B N   1 
ATOM 4543  C CA  . ALA B 1 250 ? -29.972 -1.027  69.829  1.00 83.29  ? 250 ALA B CA  1 
ATOM 4544  C C   . ALA B 1 250 ? -29.466 -1.627  68.518  1.00 88.19  ? 250 ALA B C   1 
ATOM 4545  O O   . ALA B 1 250 ? -29.853 -2.739  68.176  1.00 87.17  ? 250 ALA B O   1 
ATOM 4546  C CB  . ALA B 1 250 ? -28.839 -0.738  70.773  1.00 82.98  ? 250 ALA B CB  1 
ATOM 4547  N N   . GLU B 1 251 ? -28.593 -0.895  67.836  1.00 90.58  ? 251 GLU B N   1 
ATOM 4548  C CA  . GLU B 1 251 ? -28.141 -1.318  66.518  1.00 90.87  ? 251 GLU B CA  1 
ATOM 4549  C C   . GLU B 1 251 ? -27.069 -2.395  66.634  1.00 85.77  ? 251 GLU B C   1 
ATOM 4550  O O   . GLU B 1 251 ? -26.148 -2.286  67.450  1.00 74.05  ? 251 GLU B O   1 
ATOM 4551  C CB  . GLU B 1 251 ? -27.596 -0.123  65.734  1.00 93.54  ? 251 GLU B CB  1 
ATOM 4552  C CG  . GLU B 1 251 ? -28.541 0.415   64.667  1.00 101.93 ? 251 GLU B CG  1 
ATOM 4553  C CD  . GLU B 1 251 ? -27.870 1.407   63.731  1.00 112.49 ? 251 GLU B CD  1 
ATOM 4554  O OE1 . GLU B 1 251 ? -26.662 1.667   63.908  1.00 111.65 ? 251 GLU B OE1 1 
ATOM 4555  O OE2 . GLU B 1 251 ? -28.550 1.923   62.820  1.00 106.48 ? 251 GLU B OE2 1 
ATOM 4556  N N   . SER B 1 252 ? -27.200 -3.440  65.814  1.00 80.73  ? 252 SER B N   1 
ATOM 4557  C CA  . SER B 1 252 ? -26.202 -4.504  65.704  1.00 78.05  ? 252 SER B CA  1 
ATOM 4558  C C   . SER B 1 252 ? -25.936 -5.176  67.052  1.00 77.62  ? 252 SER B C   1 
ATOM 4559  O O   . SER B 1 252 ? -24.801 -5.532  67.375  1.00 72.57  ? 252 SER B O   1 
ATOM 4560  C CB  . SER B 1 252 ? -24.902 -3.974  65.095  1.00 76.81  ? 252 SER B CB  1 
ATOM 4561  O OG  . SER B 1 252 ? -25.141 -3.374  63.834  1.00 84.82  ? 252 SER B OG  1 
ATOM 4562  N N   . THR B 1 253 ? -26.994 -5.353  67.842  1.00 75.13  ? 253 THR B N   1 
ATOM 4563  C CA  . THR B 1 253 ? -26.890 -6.025  69.129  1.00 74.78  ? 253 THR B CA  1 
ATOM 4564  C C   . THR B 1 253 ? -27.703 -7.309  69.212  1.00 76.83  ? 253 THR B C   1 
ATOM 4565  O O   . THR B 1 253 ? -27.542 -8.055  70.185  1.00 77.83  ? 253 THR B O   1 
ATOM 4566  C CB  . THR B 1 253 ? -27.329 -5.090  70.266  1.00 76.48  ? 253 THR B CB  1 
ATOM 4567  O OG1 . THR B 1 253 ? -28.690 -4.688  70.059  1.00 86.35  ? 253 THR B OG1 1 
ATOM 4568  C CG2 . THR B 1 253 ? -26.444 -3.854  70.313  1.00 82.04  ? 253 THR B CG2 1 
ATOM 4569  N N   . VAL B 1 254 ? -28.560 -7.587  68.235  1.00 71.71  ? 254 VAL B N   1 
ATOM 4570  C CA  . VAL B 1 254 ? -29.411 -8.771  68.235  1.00 74.45  ? 254 VAL B CA  1 
ATOM 4571  C C   . VAL B 1 254 ? -28.771 -9.839  67.360  1.00 70.36  ? 254 VAL B C   1 
ATOM 4572  O O   . VAL B 1 254 ? -28.264 -9.548  66.269  1.00 70.32  ? 254 VAL B O   1 
ATOM 4573  C CB  . VAL B 1 254 ? -30.832 -8.437  67.745  1.00 70.24  ? 254 VAL B CB  1 
ATOM 4574  C CG1 . VAL B 1 254 ? -31.756 -9.631  67.929  1.00 73.30  ? 254 VAL B CG1 1 
ATOM 4575  C CG2 . VAL B 1 254 ? -31.370 -7.215  68.473  1.00 70.42  ? 254 VAL B CG2 1 
ATOM 4576  N N   . VAL B 1 255 ? -28.793 -11.079 67.838  1.00 68.05  ? 255 VAL B N   1 
ATOM 4577  C CA  . VAL B 1 255 ? -28.277 -12.226 67.105  1.00 66.54  ? 255 VAL B CA  1 
ATOM 4578  C C   . VAL B 1 255 ? -29.467 -13.075 66.680  1.00 71.20  ? 255 VAL B C   1 
ATOM 4579  O O   . VAL B 1 255 ? -30.247 -13.534 67.523  1.00 73.04  ? 255 VAL B O   1 
ATOM 4580  C CB  . VAL B 1 255 ? -27.285 -13.039 67.952  1.00 60.90  ? 255 VAL B CB  1 
ATOM 4581  C CG1 . VAL B 1 255 ? -26.698 -14.179 67.136  1.00 61.52  ? 255 VAL B CG1 1 
ATOM 4582  C CG2 . VAL B 1 255 ? -26.185 -12.137 68.484  1.00 70.18  ? 255 VAL B CG2 1 
ATOM 4583  N N   . PHE B 1 256 ? -29.619 -13.265 65.375  1.00 68.26  ? 256 PHE B N   1 
ATOM 4584  C CA  . PHE B 1 256 ? -30.695 -14.084 64.835  1.00 64.29  ? 256 PHE B CA  1 
ATOM 4585  C C   . PHE B 1 256 ? -30.225 -15.526 64.718  1.00 62.77  ? 256 PHE B C   1 
ATOM 4586  O O   . PHE B 1 256 ? -29.189 -15.803 64.107  1.00 65.12  ? 256 PHE B O   1 
ATOM 4587  C CB  . PHE B 1 256 ? -31.150 -13.556 63.475  1.00 67.39  ? 256 PHE B CB  1 
ATOM 4588  C CG  . PHE B 1 256 ? -32.237 -14.373 62.842  1.00 77.15  ? 256 PHE B CG  1 
ATOM 4589  C CD1 . PHE B 1 256 ? -33.515 -14.380 63.377  1.00 75.25  ? 256 PHE B CD1 1 
ATOM 4590  C CD2 . PHE B 1 256 ? -31.986 -15.130 61.712  1.00 72.45  ? 256 PHE B CD2 1 
ATOM 4591  C CE1 . PHE B 1 256 ? -34.519 -15.130 62.800  1.00 66.73  ? 256 PHE B CE1 1 
ATOM 4592  C CE2 . PHE B 1 256 ? -32.989 -15.885 61.129  1.00 72.79  ? 256 PHE B CE2 1 
ATOM 4593  C CZ  . PHE B 1 256 ? -34.257 -15.883 61.672  1.00 74.97  ? 256 PHE B CZ  1 
ATOM 4594  N N   . VAL B 1 257 ? -30.980 -16.440 65.320  1.00 69.49  ? 257 VAL B N   1 
ATOM 4595  C CA  . VAL B 1 257 ? -30.646 -17.856 65.348  1.00 66.27  ? 257 VAL B CA  1 
ATOM 4596  C C   . VAL B 1 257 ? -31.742 -18.609 64.618  1.00 67.09  ? 257 VAL B C   1 
ATOM 4597  O O   . VAL B 1 257 ? -32.931 -18.415 64.897  1.00 75.72  ? 257 VAL B O   1 
ATOM 4598  C CB  . VAL B 1 257 ? -30.488 -18.379 66.788  1.00 69.53  ? 257 VAL B CB  1 
ATOM 4599  C CG1 . VAL B 1 257 ? -29.981 -19.819 66.773  1.00 69.55  ? 257 VAL B CG1 1 
ATOM 4600  C CG2 . VAL B 1 257 ? -29.545 -17.478 67.570  1.00 67.29  ? 257 VAL B CG2 1 
ATOM 4601  N N   . CYS B 1 258 ? -31.336 -19.423 63.634  1.00 66.05  ? 258 CYS B N   1 
ATOM 4602  C CA  . CYS B 1 258 ? -32.299 -20.288 62.906  1.00 65.71  ? 258 CYS B CA  1 
ATOM 4603  C C   . CYS B 1 258 ? -31.541 -21.422 62.226  1.00 59.92  ? 258 CYS B C   1 
ATOM 4604  O O   . CYS B 1 258 ? -30.472 -21.159 61.683  1.00 63.62  ? 258 CYS B O   1 
ATOM 4605  C CB  . CYS B 1 258 ? -33.085 -19.523 61.858  1.00 56.68  ? 258 CYS B CB  1 
ATOM 4606  S SG  . CYS B 1 258 ? -34.475 -20.472 61.193  1.00 70.13  ? 258 CYS B SG  1 
ATOM 4607  N N   . PHE B 1 259 ? -32.078 -22.642 62.280  1.00 65.09  ? 259 PHE B N   1 
ATOM 4608  C CA  . PHE B 1 259 ? -31.431 -23.797 61.605  1.00 65.95  ? 259 PHE B CA  1 
ATOM 4609  C C   . PHE B 1 259 ? -32.350 -24.288 60.485  1.00 70.57  ? 259 PHE B C   1 
ATOM 4610  O O   . PHE B 1 259 ? -32.502 -25.512 60.326  1.00 77.47  ? 259 PHE B O   1 
ATOM 4611  C CB  . PHE B 1 259 ? -31.038 -24.861 62.632  1.00 68.39  ? 259 PHE B CB  1 
ATOM 4612  C CG  . PHE B 1 259 ? -30.137 -24.331 63.719  1.00 68.74  ? 259 PHE B CG  1 
ATOM 4613  C CD1 . PHE B 1 259 ? -28.862 -23.877 63.424  1.00 70.50  ? 259 PHE B CD1 1 
ATOM 4614  C CD2 . PHE B 1 259 ? -30.577 -24.251 65.032  1.00 70.14  ? 259 PHE B CD2 1 
ATOM 4615  C CE1 . PHE B 1 259 ? -28.039 -23.375 64.418  1.00 71.81  ? 259 PHE B CE1 1 
ATOM 4616  C CE2 . PHE B 1 259 ? -29.751 -23.752 66.027  1.00 72.20  ? 259 PHE B CE2 1 
ATOM 4617  C CZ  . PHE B 1 259 ? -28.484 -23.315 65.718  1.00 66.28  ? 259 PHE B CZ  1 
ATOM 4618  N N   . GLY B 1 260 ? -32.948 -23.350 59.742  1.00 73.31  ? 260 GLY B N   1 
ATOM 4619  C CA  . GLY B 1 260 ? -33.849 -23.709 58.630  1.00 80.16  ? 260 GLY B CA  1 
ATOM 4620  C C   . GLY B 1 260 ? -34.956 -24.645 59.074  1.00 94.47  ? 260 GLY B C   1 
ATOM 4621  O O   . GLY B 1 260 ? -35.607 -24.348 60.097  1.00 91.91  ? 260 GLY B O   1 
ATOM 4622  N N   . SER B 1 261 ? -35.148 -25.754 58.354  1.00 98.89  ? 261 SER B N   1 
ATOM 4623  C CA  . SER B 1 261 ? -36.167 -26.765 58.740  1.00 98.09  ? 261 SER B CA  1 
ATOM 4624  C C   . SER B 1 261 ? -35.577 -28.163 58.538  1.00 106.51 ? 261 SER B C   1 
ATOM 4625  O O   . SER B 1 261 ? -36.348 -29.141 58.583  1.00 103.73 ? 261 SER B O   1 
ATOM 4626  C CB  . SER B 1 261 ? -37.430 -26.589 57.942  1.00 89.00  ? 261 SER B CB  1 
ATOM 4627  O OG  . SER B 1 261 ? -37.174 -26.764 56.556  1.00 107.45 ? 261 SER B OG  1 
ATOM 4628  N N   . GLU B 1 262 ? -34.261 -28.243 58.324  1.00 107.99 ? 262 GLU B N   1 
ATOM 4629  C CA  . GLU B 1 262 ? -33.600 -29.550 58.061  1.00 104.06 ? 262 GLU B CA  1 
ATOM 4630  C C   . GLU B 1 262 ? -33.727 -30.454 59.292  1.00 106.03 ? 262 GLU B C   1 
ATOM 4631  O O   . GLU B 1 262 ? -34.183 -31.603 59.131  1.00 115.39 ? 262 GLU B O   1 
ATOM 4632  C CB  . GLU B 1 262 ? -32.132 -29.331 57.696  1.00 100.19 ? 262 GLU B CB  1 
ATOM 4633  C CG  . GLU B 1 262 ? -31.937 -28.622 56.370  1.00 96.86  ? 262 GLU B CG  1 
ATOM 4634  C CD  . GLU B 1 262 ? -30.493 -28.320 56.001  1.00 96.30  ? 262 GLU B CD  1 
ATOM 4635  O OE1 . GLU B 1 262 ? -29.614 -28.491 56.865  1.00 104.11 ? 262 GLU B OE1 1 
ATOM 4636  O OE2 . GLU B 1 262 ? -30.250 -27.922 54.847  1.00 88.11  ? 262 GLU B OE2 1 
ATOM 4637  N N   . TYR B 1 263 ? -33.341 -29.952 60.470  1.00 98.47  ? 263 TYR B N   1 
ATOM 4638  C CA  . TYR B 1 263 ? -33.374 -30.775 61.700  1.00 105.35 ? 263 TYR B CA  1 
ATOM 4639  C C   . TYR B 1 263 ? -33.843 -29.923 62.881  1.00 113.60 ? 263 TYR B C   1 
ATOM 4640  O O   . TYR B 1 263 ? -33.188 -28.899 63.164  1.00 118.34 ? 263 TYR B O   1 
ATOM 4641  C CB  . TYR B 1 263 ? -32.000 -31.380 61.989  1.00 107.74 ? 263 TYR B CB  1 
ATOM 4642  C CG  . TYR B 1 263 ? -30.923 -30.353 62.264  1.00 108.57 ? 263 TYR B CG  1 
ATOM 4643  C CD1 . TYR B 1 263 ? -30.690 -29.891 63.554  1.00 111.58 ? 263 TYR B CD1 1 
ATOM 4644  C CD2 . TYR B 1 263 ? -30.141 -29.850 61.233  1.00 109.03 ? 263 TYR B CD2 1 
ATOM 4645  C CE1 . TYR B 1 263 ? -29.708 -28.954 63.807  1.00 112.05 ? 263 TYR B CE1 1 
ATOM 4646  C CE2 . TYR B 1 263 ? -29.155 -28.911 61.480  1.00 107.61 ? 263 TYR B CE2 1 
ATOM 4647  C CZ  . TYR B 1 263 ? -28.943 -28.467 62.768  1.00 110.36 ? 263 TYR B CZ  1 
ATOM 4648  O OH  . TYR B 1 263 ? -27.965 -27.533 63.019  1.00 101.75 ? 263 TYR B OH  1 
ATOM 4649  N N   . PHE B 1 264 ? -34.938 -30.325 63.532  1.00 110.93 ? 264 PHE B N   1 
ATOM 4650  C CA  . PHE B 1 264 ? -35.418 -29.608 64.743  1.00 118.17 ? 264 PHE B CA  1 
ATOM 4651  C C   . PHE B 1 264 ? -34.471 -29.943 65.897  1.00 113.57 ? 264 PHE B C   1 
ATOM 4652  O O   . PHE B 1 264 ? -34.800 -29.560 67.042  1.00 113.17 ? 264 PHE B O   1 
ATOM 4653  C CB  . PHE B 1 264 ? -36.861 -30.016 65.061  1.00 128.94 ? 264 PHE B CB  1 
ATOM 4654  C CG  . PHE B 1 264 ? -37.033 -31.370 65.707  1.00 129.63 ? 264 PHE B CG  1 
ATOM 4655  C CD1 . PHE B 1 264 ? -36.816 -32.537 64.991  1.00 127.36 ? 264 PHE B CD1 1 
ATOM 4656  C CD2 . PHE B 1 264 ? -37.427 -31.479 67.032  1.00 129.74 ? 264 PHE B CD2 1 
ATOM 4657  C CE1 . PHE B 1 264 ? -36.973 -33.778 65.589  1.00 130.59 ? 264 PHE B CE1 1 
ATOM 4658  C CE2 . PHE B 1 264 ? -37.581 -32.720 67.629  1.00 129.17 ? 264 PHE B CE2 1 
ATOM 4659  C CZ  . PHE B 1 264 ? -37.357 -33.867 66.906  1.00 132.93 ? 264 PHE B CZ  1 
ATOM 4660  N N   . LEU B 1 265 ? -33.352 -30.624 65.602  1.00 111.21 ? 265 LEU B N   1 
ATOM 4661  C CA  . LEU B 1 265 ? -32.382 -31.068 66.645  1.00 111.64 ? 265 LEU B CA  1 
ATOM 4662  C C   . LEU B 1 265 ? -33.100 -32.046 67.580  1.00 111.29 ? 265 LEU B C   1 
ATOM 4663  O O   . LEU B 1 265 ? -33.883 -32.873 67.069  1.00 120.27 ? 265 LEU B O   1 
ATOM 4664  C CB  . LEU B 1 265 ? -31.786 -29.871 67.398  1.00 114.89 ? 265 LEU B CB  1 
ATOM 4665  C CG  . LEU B 1 265 ? -30.830 -30.212 68.541  1.00 118.84 ? 265 LEU B CG  1 
ATOM 4666  C CD1 . LEU B 1 265 ? -29.598 -30.938 68.025  1.00 117.20 ? 265 LEU B CD1 1 
ATOM 4667  C CD2 . LEU B 1 265 ? -30.433 -28.961 69.311  1.00 112.28 ? 265 LEU B CD2 1 
ATOM 4668  N N   . SER B 1 266 ? -32.836 -31.962 68.884  1.00 107.34 ? 266 SER B N   1 
ATOM 4669  C CA  . SER B 1 266 ? -33.522 -32.836 69.871  1.00 113.72 ? 266 SER B CA  1 
ATOM 4670  C C   . SER B 1 266 ? -33.489 -32.139 71.230  1.00 113.50 ? 266 SER B C   1 
ATOM 4671  O O   . SER B 1 266 ? -32.786 -31.143 71.331  1.00 111.18 ? 266 SER B O   1 
ATOM 4672  C CB  . SER B 1 266 ? -32.864 -34.187 69.949  1.00 111.46 ? 266 SER B CB  1 
ATOM 4673  O OG  . SER B 1 266 ? -31.601 -34.094 70.591  1.00 116.54 ? 266 SER B OG  1 
ATOM 4674  N N   . ASN B 1 267 ? -34.225 -32.642 72.221  1.00 112.45 ? 267 ASN B N   1 
ATOM 4675  C CA  . ASN B 1 267 ? -34.189 -32.072 73.593  1.00 111.30 ? 267 ASN B CA  1 
ATOM 4676  C C   . ASN B 1 267 ? -32.750 -32.078 74.107  1.00 113.65 ? 267 ASN B C   1 
ATOM 4677  O O   . ASN B 1 267 ? -32.464 -31.354 75.073  1.00 112.45 ? 267 ASN B O   1 
ATOM 4678  C CB  . ASN B 1 267 ? -35.161 -32.764 74.550  1.00 116.90 ? 267 ASN B CB  1 
ATOM 4679  C CG  . ASN B 1 267 ? -34.670 -34.100 75.064  1.00 124.27 ? 267 ASN B CG  1 
ATOM 4680  O OD1 . ASN B 1 267 ? -34.239 -34.207 76.209  1.00 126.05 ? 267 ASN B OD1 1 
ATOM 4681  N ND2 . ASN B 1 267 ? -34.757 -35.127 74.236  1.00 127.44 ? 267 ASN B ND2 1 
ATOM 4682  N N   . GLU B 1 268 ? -31.878 -32.863 73.476  1.00 114.52 ? 268 GLU B N   1 
ATOM 4683  C CA  . GLU B 1 268 ? -30.490 -32.956 73.973  1.00 111.33 ? 268 GLU B CA  1 
ATOM 4684  C C   . GLU B 1 268 ? -29.677 -31.865 73.288  1.00 107.67 ? 268 GLU B C   1 
ATOM 4685  O O   . GLU B 1 268 ? -28.763 -31.313 73.926  1.00 107.07 ? 268 GLU B O   1 
ATOM 4686  C CB  . GLU B 1 268 ? -29.925 -34.335 73.649  1.00 107.84 ? 268 GLU B CB  1 
ATOM 4687  C CG  . GLU B 1 268 ? -30.040 -35.317 74.800  1.00 117.95 ? 268 GLU B CG  1 
ATOM 4688  C CD  . GLU B 1 268 ? -31.426 -35.909 74.997  1.00 119.62 ? 268 GLU B CD  1 
ATOM 4689  O OE1 . GLU B 1 268 ? -32.093 -36.189 73.985  1.00 129.05 ? 268 GLU B OE1 1 
ATOM 4690  O OE2 . GLU B 1 268 ? -31.834 -36.084 76.161  1.00 111.79 ? 268 GLU B OE2 1 
ATOM 4691  N N   . GLU B 1 269 ? -30.012 -31.580 72.035  1.00 106.27 ? 269 GLU B N   1 
ATOM 4692  C CA  . GLU B 1 269 ? -29.237 -30.578 71.275  1.00 108.59 ? 269 GLU B CA  1 
ATOM 4693  C C   . GLU B 1 269 ? -29.869 -29.203 71.471  1.00 103.80 ? 269 GLU B C   1 
ATOM 4694  O O   . GLU B 1 269 ? -29.108 -28.228 71.489  1.00 98.67  ? 269 GLU B O   1 
ATOM 4695  C CB  . GLU B 1 269 ? -29.100 -31.019 69.823  1.00 109.48 ? 269 GLU B CB  1 
ATOM 4696  C CG  . GLU B 1 269 ? -28.612 -32.451 69.685  1.00 111.58 ? 269 GLU B CG  1 
ATOM 4697  C CD  . GLU B 1 269 ? -27.659 -32.705 68.528  1.00 116.22 ? 269 GLU B CD  1 
ATOM 4698  O OE1 . GLU B 1 269 ? -26.902 -31.782 68.171  1.00 119.99 ? 269 GLU B OE1 1 
ATOM 4699  O OE2 . GLU B 1 269 ? -27.682 -33.825 67.980  1.00 112.42 ? 269 GLU B OE2 1 
ATOM 4700  N N   . LEU B 1 270 ? -31.197 -29.122 71.620  1.00 99.94  ? 270 LEU B N   1 
ATOM 4701  C CA  . LEU B 1 270 ? -31.732 -27.800 71.921  1.00 94.45  ? 270 LEU B CA  1 
ATOM 4702  C C   . LEU B 1 270 ? -31.139 -27.240 73.205  1.00 95.75  ? 270 LEU B C   1 
ATOM 4703  O O   . LEU B 1 270 ? -30.983 -26.022 73.333  1.00 95.70  ? 270 LEU B O   1 
ATOM 4704  C CB  . LEU B 1 270 ? -33.256 -27.855 72.038  1.00 100.23 ? 270 LEU B CB  1 
ATOM 4705  C CG  . LEU B 1 270 ? -34.090 -28.070 70.773  1.00 98.46  ? 270 LEU B CG  1 
ATOM 4706  C CD1 . LEU B 1 270 ? -35.521 -28.428 71.141  1.00 93.60  ? 270 LEU B CD1 1 
ATOM 4707  C CD2 . LEU B 1 270 ? -34.056 -26.841 69.884  1.00 97.98  ? 270 LEU B CD2 1 
ATOM 4708  N N   . GLU B 1 271 ? -30.810 -28.110 74.163  1.00 97.99  ? 271 GLU B N   1 
ATOM 4709  C CA  . GLU B 1 271 ? -30.263 -27.640 75.434  1.00 98.06  ? 271 GLU B CA  1 
ATOM 4710  C C   . GLU B 1 271 ? -28.925 -26.936 75.240  1.00 96.69  ? 271 GLU B C   1 
ATOM 4711  O O   . GLU B 1 271 ? -28.681 -25.859 75.807  1.00 96.71  ? 271 GLU B O   1 
ATOM 4712  C CB  . GLU B 1 271 ? -30.118 -28.811 76.407  1.00 106.25 ? 271 GLU B CB  1 
ATOM 4713  C CG  . GLU B 1 271 ? -31.190 -28.851 77.482  1.00 105.35 ? 271 GLU B CG  1 
ATOM 4714  C CD  . GLU B 1 271 ? -31.083 -27.683 78.443  1.00 111.06 ? 271 GLU B CD  1 
ATOM 4715  O OE1 . GLU B 1 271 ? -29.959 -27.395 78.902  1.00 104.61 ? 271 GLU B OE1 1 
ATOM 4716  O OE2 . GLU B 1 271 ? -32.120 -27.052 78.732  1.00 120.83 ? 271 GLU B OE2 1 
ATOM 4717  N N   . GLU B 1 272 ? -28.034 -27.536 74.443  1.00 97.57  ? 272 GLU B N   1 
ATOM 4718  C CA  . GLU B 1 272 ? -26.689 -27.000 74.278  1.00 90.95  ? 272 GLU B CA  1 
ATOM 4719  C C   . GLU B 1 272 ? -26.685 -25.644 73.583  1.00 88.84  ? 272 GLU B C   1 
ATOM 4720  O O   . GLU B 1 272 ? -25.725 -24.884 73.747  1.00 94.64  ? 272 GLU B O   1 
ATOM 4721  C CB  . GLU B 1 272 ? -25.819 -27.985 73.494  1.00 91.88  ? 272 GLU B CB  1 
ATOM 4722  C CG  . GLU B 1 272 ? -25.698 -29.370 74.119  1.00 99.23  ? 272 GLU B CG  1 
ATOM 4723  C CD  . GLU B 1 272 ? -24.609 -29.458 75.179  1.00 109.31 ? 272 GLU B CD  1 
ATOM 4724  O OE1 . GLU B 1 272 ? -24.138 -28.403 75.653  1.00 106.17 ? 272 GLU B OE1 1 
ATOM 4725  O OE2 . GLU B 1 272 ? -24.220 -30.592 75.535  1.00 115.31 ? 272 GLU B OE2 1 
ATOM 4726  N N   . VAL B 1 273 ? -27.724 -25.327 72.812  1.00 90.78  ? 273 VAL B N   1 
ATOM 4727  C CA  . VAL B 1 273 ? -27.776 -24.041 72.122  1.00 91.95  ? 273 VAL B CA  1 
ATOM 4728  C C   . VAL B 1 273 ? -28.559 -23.046 72.968  1.00 96.24  ? 273 VAL B C   1 
ATOM 4729  O O   . VAL B 1 273 ? -28.244 -21.852 72.982  1.00 95.53  ? 273 VAL B O   1 
ATOM 4730  C CB  . VAL B 1 273 ? -28.374 -24.180 70.706  1.00 87.90  ? 273 VAL B CB  1 
ATOM 4731  C CG1 . VAL B 1 273 ? -27.623 -25.242 69.916  1.00 84.47  ? 273 VAL B CG1 1 
ATOM 4732  C CG2 . VAL B 1 273 ? -29.861 -24.503 70.761  1.00 94.13  ? 273 VAL B CG2 1 
ATOM 4733  N N   . ALA B 1 274 ? -29.547 -23.530 73.729  1.00 95.74  ? 274 ALA B N   1 
ATOM 4734  C CA  . ALA B 1 274 ? -30.324 -22.635 74.577  1.00 91.63  ? 274 ALA B CA  1 
ATOM 4735  C C   . ALA B 1 274 ? -29.472 -22.082 75.713  1.00 95.65  ? 274 ALA B C   1 
ATOM 4736  O O   . ALA B 1 274 ? -29.447 -20.869 75.954  1.00 95.05  ? 274 ALA B O   1 
ATOM 4737  C CB  . ALA B 1 274 ? -31.552 -23.361 75.123  1.00 88.57  ? 274 ALA B CB  1 
ATOM 4738  N N   . ILE B 1 275 ? -28.760 -22.960 76.426  1.00 94.65  ? 275 ILE B N   1 
ATOM 4739  C CA  . ILE B 1 275 ? -27.908 -22.475 77.508  1.00 93.78  ? 275 ILE B CA  1 
ATOM 4740  C C   . ILE B 1 275 ? -26.717 -21.705 76.945  1.00 95.63  ? 275 ILE B C   1 
ATOM 4741  O O   . ILE B 1 275 ? -26.216 -20.768 77.582  1.00 95.68  ? 275 ILE B O   1 
ATOM 4742  C CB  . ILE B 1 275 ? -27.471 -23.643 78.409  1.00 96.15  ? 275 ILE B CB  1 
ATOM 4743  C CG1 . ILE B 1 275 ? -28.701 -24.385 78.932  1.00 97.02  ? 275 ILE B CG1 1 
ATOM 4744  C CG2 . ILE B 1 275 ? -26.635 -23.143 79.577  1.00 102.20 ? 275 ILE B CG2 1 
ATOM 4745  C CD1 . ILE B 1 275 ? -29.686 -23.493 79.666  1.00 95.62  ? 275 ILE B CD1 1 
ATOM 4746  N N   . GLY B 1 276 ? -26.255 -22.066 75.744  1.00 94.18  ? 276 GLY B N   1 
ATOM 4747  C CA  . GLY B 1 276 ? -25.207 -21.293 75.101  1.00 91.99  ? 276 GLY B CA  1 
ATOM 4748  C C   . GLY B 1 276 ? -25.645 -19.887 74.743  1.00 91.64  ? 276 GLY B C   1 
ATOM 4749  O O   . GLY B 1 276 ? -24.842 -18.949 74.788  1.00 93.86  ? 276 GLY B O   1 
ATOM 4750  N N   . LEU B 1 277 ? -26.915 -19.716 74.375  1.00 82.25  ? 277 LEU B N   1 
ATOM 4751  C CA  . LEU B 1 277 ? -27.461 -18.384 74.148  1.00 83.26  ? 277 LEU B CA  1 
ATOM 4752  C C   . LEU B 1 277 ? -27.720 -17.649 75.455  1.00 90.74  ? 277 LEU B C   1 
ATOM 4753  O O   . LEU B 1 277 ? -27.657 -16.414 75.489  1.00 90.81  ? 277 LEU B O   1 
ATOM 4754  C CB  . LEU B 1 277 ? -28.756 -18.473 73.339  1.00 83.63  ? 277 LEU B CB  1 
ATOM 4755  C CG  . LEU B 1 277 ? -28.614 -18.810 71.853  1.00 82.97  ? 277 LEU B CG  1 
ATOM 4756  C CD1 . LEU B 1 277 ? -29.974 -19.088 71.237  1.00 88.59  ? 277 LEU B CD1 1 
ATOM 4757  C CD2 . LEU B 1 277 ? -27.919 -17.677 71.119  1.00 79.55  ? 277 LEU B CD2 1 
ATOM 4758  N N   . GLU B 1 278 ? -28.012 -18.380 76.536  1.00 92.27  ? 278 GLU B N   1 
ATOM 4759  C CA  . GLU B 1 278 ? -28.235 -17.725 77.822  1.00 84.64  ? 278 GLU B CA  1 
ATOM 4760  C C   . GLU B 1 278 ? -26.953 -17.093 78.347  1.00 85.94  ? 278 GLU B C   1 
ATOM 4761  O O   . GLU B 1 278 ? -26.940 -15.916 78.726  1.00 87.16  ? 278 GLU B O   1 
ATOM 4762  C CB  . GLU B 1 278 ? -28.796 -18.722 78.840  1.00 95.72  ? 278 GLU B CB  1 
ATOM 4763  C CG  . GLU B 1 278 ? -29.037 -18.110 80.216  1.00 103.75 ? 278 GLU B CG  1 
ATOM 4764  C CD  . GLU B 1 278 ? -29.657 -19.089 81.196  1.00 105.42 ? 278 GLU B CD  1 
ATOM 4765  O OE1 . GLU B 1 278 ? -29.920 -20.244 80.804  1.00 106.89 ? 278 GLU B OE1 1 
ATOM 4766  O OE2 . GLU B 1 278 ? -29.883 -18.698 82.361  1.00 100.18 ? 278 GLU B OE2 1 
ATOM 4767  N N   . ILE B 1 279 ? -25.855 -17.858 78.377  1.00 84.91  ? 279 ILE B N   1 
ATOM 4768  C CA  . ILE B 1 279 ? -24.591 -17.341 78.897  1.00 85.32  ? 279 ILE B CA  1 
ATOM 4769  C C   . ILE B 1 279 ? -23.864 -16.454 77.900  1.00 89.72  ? 279 ILE B C   1 
ATOM 4770  O O   . ILE B 1 279 ? -22.803 -15.908 78.232  1.00 89.83  ? 279 ILE B O   1 
ATOM 4771  C CB  . ILE B 1 279 ? -23.651 -18.483 79.335  1.00 89.31  ? 279 ILE B CB  1 
ATOM 4772  C CG1 . ILE B 1 279 ? -23.202 -19.305 78.126  1.00 84.07  ? 279 ILE B CG1 1 
ATOM 4773  C CG2 . ILE B 1 279 ? -24.342 -19.375 80.353  1.00 94.98  ? 279 ILE B CG2 1 
ATOM 4774  C CD1 . ILE B 1 279 ? -22.161 -20.351 78.464  1.00 88.81  ? 279 ILE B CD1 1 
ATOM 4775  N N   . SER B 1 280 ? -24.398 -16.292 76.687  1.00 89.89  ? 280 SER B N   1 
ATOM 4776  C CA  . SER B 1 280 ? -23.798 -15.373 75.727  1.00 86.87  ? 280 SER B CA  1 
ATOM 4777  C C   . SER B 1 280 ? -24.001 -13.916 76.119  1.00 89.95  ? 280 SER B C   1 
ATOM 4778  O O   . SER B 1 280 ? -23.234 -13.058 75.673  1.00 101.90 ? 280 SER B O   1 
ATOM 4779  C CB  . SER B 1 280 ? -24.376 -15.620 74.333  1.00 85.30  ? 280 SER B CB  1 
ATOM 4780  O OG  . SER B 1 280 ? -24.081 -16.933 73.885  1.00 98.72  ? 280 SER B OG  1 
ATOM 4781  N N   . THR B 1 281 ? -25.011 -13.628 76.946  1.00 87.57  ? 281 THR B N   1 
ATOM 4782  C CA  . THR B 1 281 ? -25.297 -12.278 77.439  1.00 90.60  ? 281 THR B CA  1 
ATOM 4783  C C   . THR B 1 281 ? -25.458 -11.284 76.287  1.00 97.61  ? 281 THR B C   1 
ATOM 4784  O O   . THR B 1 281 ? -24.865 -10.204 76.278  1.00 108.24 ? 281 THR B O   1 
ATOM 4785  C CB  . THR B 1 281 ? -24.221 -11.806 78.424  1.00 100.95 ? 281 THR B CB  1 
ATOM 4786  O OG1 . THR B 1 281 ? -22.990 -11.577 77.726  1.00 109.74 ? 281 THR B OG1 1 
ATOM 4787  C CG2 . THR B 1 281 ? -23.998 -12.851 79.509  1.00 101.46 ? 281 THR B CG2 1 
ATOM 4788  N N   . VAL B 1 282 ? -26.277 -11.659 75.304  1.00 91.75  ? 282 VAL B N   1 
ATOM 4789  C CA  . VAL B 1 282 ? -26.561 -10.802 74.163  1.00 84.37  ? 282 VAL B CA  1 
ATOM 4790  C C   . VAL B 1 282 ? -27.985 -11.071 73.700  1.00 85.81  ? 282 VAL B C   1 
ATOM 4791  O O   . VAL B 1 282 ? -28.503 -12.184 73.839  1.00 88.20  ? 282 VAL B O   1 
ATOM 4792  C CB  . VAL B 1 282 ? -25.540 -11.017 73.018  1.00 79.91  ? 282 VAL B CB  1 
ATOM 4793  C CG1 . VAL B 1 282 ? -25.768 -12.351 72.323  1.00 86.00  ? 282 VAL B CG1 1 
ATOM 4794  C CG2 . VAL B 1 282 ? -25.588 -9.863  72.025  1.00 77.50  ? 282 VAL B CG2 1 
ATOM 4795  N N   . ASN B 1 283 ? -28.628 -10.034 73.168  1.00 83.69  ? 283 ASN B N   1 
ATOM 4796  C CA  . ASN B 1 283 ? -29.987 -10.167 72.665  1.00 90.13  ? 283 ASN B CA  1 
ATOM 4797  C C   . ASN B 1 283 ? -30.024 -11.128 71.483  1.00 84.20  ? 283 ASN B C   1 
ATOM 4798  O O   . ASN B 1 283 ? -29.089 -11.203 70.686  1.00 76.19  ? 283 ASN B O   1 
ATOM 4799  C CB  . ASN B 1 283 ? -30.532 -8.802  72.242  1.00 91.83  ? 283 ASN B CB  1 
ATOM 4800  C CG  . ASN B 1 283 ? -30.297 -7.733  73.287  1.00 94.05  ? 283 ASN B CG  1 
ATOM 4801  O OD1 . ASN B 1 283 ? -30.414 -7.987  74.486  1.00 101.72 ? 283 ASN B OD1 1 
ATOM 4802  N ND2 . ASN B 1 283 ? -29.958 -6.531  72.836  1.00 83.62  ? 283 ASN B ND2 1 
ATOM 4803  N N   . PHE B 1 284 ? -31.126 -11.862 71.362  1.00 84.02  ? 284 PHE B N   1 
ATOM 4804  C CA  . PHE B 1 284 ? -31.236 -12.841 70.291  1.00 79.13  ? 284 PHE B CA  1 
ATOM 4805  C C   . PHE B 1 284 ? -32.695 -13.040 69.909  1.00 78.70  ? 284 PHE B C   1 
ATOM 4806  O O   . PHE B 1 284 ? -33.606 -12.822 70.713  1.00 82.82  ? 284 PHE B O   1 
ATOM 4807  C CB  . PHE B 1 284 ? -30.609 -14.185 70.691  1.00 83.17  ? 284 PHE B CB  1 
ATOM 4808  C CG  . PHE B 1 284 ? -31.374 -14.919 71.754  1.00 81.64  ? 284 PHE B CG  1 
ATOM 4809  C CD1 . PHE B 1 284 ? -31.168 -14.637 73.093  1.00 88.14  ? 284 PHE B CD1 1 
ATOM 4810  C CD2 . PHE B 1 284 ? -32.297 -15.895 71.414  1.00 81.67  ? 284 PHE B CD2 1 
ATOM 4811  C CE1 . PHE B 1 284 ? -31.871 -15.308 74.072  1.00 90.16  ? 284 PHE B CE1 1 
ATOM 4812  C CE2 . PHE B 1 284 ? -33.004 -16.569 72.389  1.00 86.49  ? 284 PHE B CE2 1 
ATOM 4813  C CZ  . PHE B 1 284 ? -32.790 -16.278 73.720  1.00 87.07  ? 284 PHE B CZ  1 
ATOM 4814  N N   . ILE B 1 285 ? -32.896 -13.451 68.663  1.00 77.92  ? 285 ILE B N   1 
ATOM 4815  C CA  . ILE B 1 285 ? -34.179 -13.943 68.175  1.00 70.08  ? 285 ILE B CA  1 
ATOM 4816  C C   . ILE B 1 285 ? -33.919 -15.350 67.655  1.00 74.04  ? 285 ILE B C   1 
ATOM 4817  O O   . ILE B 1 285 ? -33.412 -15.529 66.544  1.00 72.70  ? 285 ILE B O   1 
ATOM 4818  C CB  . ILE B 1 285 ? -34.779 -13.046 67.089  1.00 76.84  ? 285 ILE B CB  1 
ATOM 4819  C CG1 . ILE B 1 285 ? -34.958 -11.623 67.613  1.00 79.16  ? 285 ILE B CG1 1 
ATOM 4820  C CG2 . ILE B 1 285 ? -36.112 -13.609 66.617  1.00 77.63  ? 285 ILE B CG2 1 
ATOM 4821  C CD1 . ILE B 1 285 ? -35.651 -10.697 66.638  1.00 83.13  ? 285 ILE B CD1 1 
ATOM 4822  N N   . TRP B 1 286 ? -34.239 -16.353 68.468  1.00 78.93  ? 286 TRP B N   1 
ATOM 4823  C CA  . TRP B 1 286 ? -33.990 -17.753 68.135  1.00 76.64  ? 286 TRP B CA  1 
ATOM 4824  C C   . TRP B 1 286 ? -35.299 -18.363 67.647  1.00 79.87  ? 286 TRP B C   1 
ATOM 4825  O O   . TRP B 1 286 ? -36.163 -18.728 68.444  1.00 84.54  ? 286 TRP B O   1 
ATOM 4826  C CB  . TRP B 1 286 ? -33.438 -18.502 69.342  1.00 74.86  ? 286 TRP B CB  1 
ATOM 4827  C CG  . TRP B 1 286 ? -33.342 -19.985 69.165  1.00 75.75  ? 286 TRP B CG  1 
ATOM 4828  C CD1 . TRP B 1 286 ? -33.174 -20.667 67.992  1.00 79.04  ? 286 TRP B CD1 1 
ATOM 4829  C CD2 . TRP B 1 286 ? -33.417 -20.974 70.196  1.00 77.34  ? 286 TRP B CD2 1 
ATOM 4830  N NE1 . TRP B 1 286 ? -33.138 -22.019 68.232  1.00 77.35  ? 286 TRP B NE1 1 
ATOM 4831  C CE2 . TRP B 1 286 ? -33.283 -22.234 69.577  1.00 84.08  ? 286 TRP B CE2 1 
ATOM 4832  C CE3 . TRP B 1 286 ? -33.581 -20.918 71.583  1.00 84.86  ? 286 TRP B CE3 1 
ATOM 4833  C CZ2 . TRP B 1 286 ? -33.311 -23.425 70.300  1.00 91.06  ? 286 TRP B CZ2 1 
ATOM 4834  C CZ3 . TRP B 1 286 ? -33.608 -22.103 72.297  1.00 95.36  ? 286 TRP B CZ3 1 
ATOM 4835  C CH2 . TRP B 1 286 ? -33.472 -23.340 71.655  1.00 96.13  ? 286 TRP B CH2 1 
ATOM 4836  N N   . ALA B 1 287 ? -35.438 -18.477 66.327  1.00 80.64  ? 287 ALA B N   1 
ATOM 4837  C CA  . ALA B 1 287 ? -36.624 -19.063 65.717  1.00 76.70  ? 287 ALA B CA  1 
ATOM 4838  C C   . ALA B 1 287 ? -36.418 -20.568 65.608  1.00 80.14  ? 287 ALA B C   1 
ATOM 4839  O O   . ALA B 1 287 ? -35.570 -21.032 64.837  1.00 71.19  ? 287 ALA B O   1 
ATOM 4840  C CB  . ALA B 1 287 ? -36.890 -18.442 64.350  1.00 64.86  ? 287 ALA B CB  1 
ATOM 4841  N N   . VAL B 1 288 ? -37.149 -21.311 66.446  1.00 87.48  ? 288 VAL B N   1 
ATOM 4842  C CA  . VAL B 1 288 ? -36.970 -22.788 66.553  1.00 86.34  ? 288 VAL B CA  1 
ATOM 4843  C C   . VAL B 1 288 ? -37.906 -23.510 65.583  1.00 91.71  ? 288 VAL B C   1 
ATOM 4844  O O   . VAL B 1 288 ? -38.543 -22.817 64.805  1.00 91.24  ? 288 VAL B O   1 
ATOM 4845  C CB  . VAL B 1 288 ? -37.142 -23.229 68.018  1.00 91.37  ? 288 VAL B CB  1 
ATOM 4846  C CG1 . VAL B 1 288 ? -38.595 -23.393 68.438  1.00 91.49  ? 288 VAL B CG1 1 
ATOM 4847  C CG2 . VAL B 1 288 ? -36.320 -24.457 68.366  1.00 96.52  ? 288 VAL B CG2 1 
ATOM 4848  N N   . PHE B 1 303 ? -32.651 -20.367 81.130  1.00 115.35 ? 303 PHE B N   1 
ATOM 4849  C CA  . PHE B 1 303 ? -33.482 -20.154 79.919  1.00 115.52 ? 303 PHE B CA  1 
ATOM 4850  C C   . PHE B 1 303 ? -34.947 -20.325 80.302  1.00 115.79 ? 303 PHE B C   1 
ATOM 4851  O O   . PHE B 1 303 ? -35.582 -19.306 80.596  1.00 114.04 ? 303 PHE B O   1 
ATOM 4852  C CB  . PHE B 1 303 ? -33.098 -21.151 78.825  1.00 112.57 ? 303 PHE B CB  1 
ATOM 4853  C CG  . PHE B 1 303 ? -33.245 -20.631 77.421  1.00 105.76 ? 303 PHE B CG  1 
ATOM 4854  C CD1 . PHE B 1 303 ? -32.313 -19.755 76.892  1.00 102.90 ? 303 PHE B CD1 1 
ATOM 4855  C CD2 . PHE B 1 303 ? -34.317 -21.013 76.635  1.00 93.73  ? 303 PHE B CD2 1 
ATOM 4856  C CE1 . PHE B 1 303 ? -32.449 -19.276 75.601  1.00 96.51  ? 303 PHE B CE1 1 
ATOM 4857  C CE2 . PHE B 1 303 ? -34.453 -20.531 75.344  1.00 95.46  ? 303 PHE B CE2 1 
ATOM 4858  C CZ  . PHE B 1 303 ? -33.520 -19.662 74.831  1.00 93.64  ? 303 PHE B CZ  1 
ATOM 4859  N N   . VAL B 1 304 ? -35.454 -21.561 80.281  1.00 118.84 ? 304 VAL B N   1 
ATOM 4860  C CA  . VAL B 1 304 ? -36.881 -21.866 80.617  1.00 116.77 ? 304 VAL B CA  1 
ATOM 4861  C C   . VAL B 1 304 ? -37.829 -20.814 80.004  1.00 113.32 ? 304 VAL B C   1 
ATOM 4862  O O   . VAL B 1 304 ? -38.929 -20.619 80.562  1.00 115.19 ? 304 VAL B O   1 
ATOM 4863  C CB  . VAL B 1 304 ? -37.075 -22.149 82.123  1.00 113.61 ? 304 VAL B CB  1 
ATOM 4864  C CG1 . VAL B 1 304 ? -37.195 -20.901 82.984  1.00 114.71 ? 304 VAL B CG1 1 
ATOM 4865  C CG2 . VAL B 1 304 ? -38.209 -23.126 82.396  1.00 101.57 ? 304 VAL B CG2 1 
ATOM 4866  N N   . GLN B 1 305 ? -37.446 -20.188 78.880  1.00 108.49 ? 305 GLN B N   1 
ATOM 4867  C CA  . GLN B 1 305 ? -38.274 -19.166 78.175  1.00 104.81 ? 305 GLN B CA  1 
ATOM 4868  C C   . GLN B 1 305 ? -38.529 -17.921 79.031  1.00 104.17 ? 305 GLN B C   1 
ATOM 4869  O O   . GLN B 1 305 ? -38.920 -16.895 78.445  1.00 94.25  ? 305 GLN B O   1 
ATOM 4870  C CB  . GLN B 1 305 ? -39.537 -19.789 77.574  1.00 110.14 ? 305 GLN B CB  1 
ATOM 4871  C CG  . GLN B 1 305 ? -39.295 -20.769 76.433  1.00 113.91 ? 305 GLN B CG  1 
ATOM 4872  C CD  . GLN B 1 305 ? -40.573 -21.400 75.934  1.00 112.91 ? 305 GLN B CD  1 
ATOM 4873  O OE1 . GLN B 1 305 ? -41.563 -21.500 76.655  1.00 107.11 ? 305 GLN B OE1 1 
ATOM 4874  N NE2 . GLN B 1 305 ? -40.559 -21.835 74.686  1.00 114.53 ? 305 GLN B NE2 1 
ATOM 4875  N N   . ARG B 1 306 ? -38.268 -17.966 80.339  1.00 109.14 ? 306 ARG B N   1 
ATOM 4876  C CA  . ARG B 1 306 ? -38.622 -16.823 81.217  1.00 107.69 ? 306 ARG B CA  1 
ATOM 4877  C C   . ARG B 1 306 ? -37.365 -16.198 81.814  1.00 105.82 ? 306 ARG B C   1 
ATOM 4878  O O   . ARG B 1 306 ? -37.474 -15.098 82.366  1.00 106.30 ? 306 ARG B O   1 
ATOM 4879  C CB  . ARG B 1 306 ? -39.572 -17.295 82.320  1.00 107.55 ? 306 ARG B CB  1 
ATOM 4880  C CG  . ARG B 1 306 ? -40.951 -17.705 81.824  1.00 99.30  ? 306 ARG B CG  1 
ATOM 4881  C CD  . ARG B 1 306 ? -41.643 -16.610 81.033  1.00 100.59 ? 306 ARG B CD  1 
ATOM 4882  N NE  . ARG B 1 306 ? -42.792 -17.102 80.286  1.00 102.23 ? 306 ARG B NE  1 
ATOM 4883  C CZ  . ARG B 1 306 ? -43.335 -16.481 79.244  1.00 107.06 ? 306 ARG B CZ  1 
ATOM 4884  N NH1 . ARG B 1 306 ? -42.832 -15.334 78.820  1.00 109.97 ? 306 ARG B NH1 1 
ATOM 4885  N NH2 . ARG B 1 306 ? -44.380 -17.006 78.630  1.00 105.61 ? 306 ARG B NH2 1 
ATOM 4886  N N   . VAL B 1 307 ? -36.220 -16.880 81.707  1.00 107.50 ? 307 VAL B N   1 
ATOM 4887  C CA  . VAL B 1 307 ? -34.926 -16.300 82.176  1.00 109.92 ? 307 VAL B CA  1 
ATOM 4888  C C   . VAL B 1 307 ? -34.019 -16.141 80.950  1.00 107.20 ? 307 VAL B C   1 
ATOM 4889  O O   . VAL B 1 307 ? -32.829 -15.812 81.130  1.00 111.34 ? 307 VAL B O   1 
ATOM 4890  C CB  . VAL B 1 307 ? -34.260 -17.160 83.268  1.00 109.99 ? 307 VAL B CB  1 
ATOM 4891  C CG1 . VAL B 1 307 ? -32.888 -16.627 83.652  1.00 109.53 ? 307 VAL B CG1 1 
ATOM 4892  C CG2 . VAL B 1 307 ? -35.137 -17.290 84.504  1.00 110.17 ? 307 VAL B CG2 1 
ATOM 4893  N N   . GLY B 1 308 ? -34.627 -16.090 79.762  1.00 106.13 ? 308 GLY B N   1 
ATOM 4894  C CA  . GLY B 1 308 ? -33.842 -15.826 78.542  1.00 110.26 ? 308 GLY B CA  1 
ATOM 4895  C C   . GLY B 1 308 ? -33.287 -14.420 78.591  1.00 116.19 ? 308 GLY B C   1 
ATOM 4896  O O   . GLY B 1 308 ? -34.094 -13.499 78.786  1.00 107.51 ? 308 GLY B O   1 
ATOM 4897  N N   . ASP B 1 309 ? -31.963 -14.259 78.455  1.00 118.98 ? 309 ASP B N   1 
ATOM 4898  C CA  . ASP B 1 309 ? -31.310 -12.923 78.528  1.00 111.70 ? 309 ASP B CA  1 
ATOM 4899  C C   . ASP B 1 309 ? -31.759 -12.087 77.340  1.00 112.48 ? 309 ASP B C   1 
ATOM 4900  O O   . ASP B 1 309 ? -30.987 -11.985 76.379  1.00 100.91 ? 309 ASP B O   1 
ATOM 4901  C CB  . ASP B 1 309 ? -29.784 -13.017 78.553  1.00 108.98 ? 309 ASP B CB  1 
ATOM 4902  C CG  . ASP B 1 309 ? -29.108 -11.771 79.097  1.00 115.20 ? 309 ASP B CG  1 
ATOM 4903  O OD1 . ASP B 1 309 ? -29.007 -11.653 80.332  1.00 121.00 ? 309 ASP B OD1 1 
ATOM 4904  O OD2 . ASP B 1 309 ? -28.683 -10.932 78.284  1.00 109.03 ? 309 ASP B OD2 1 
ATOM 4905  N N   . ARG B 1 310 ? -32.972 -11.545 77.404  1.00 113.93 ? 310 ARG B N   1 
ATOM 4906  C CA  . ARG B 1 310 ? -33.480 -10.659 76.331  1.00 106.68 ? 310 ARG B CA  1 
ATOM 4907  C C   . ARG B 1 310 ? -33.493 -11.406 74.999  1.00 100.26 ? 310 ARG B C   1 
ATOM 4908  O O   . ARG B 1 310 ? -32.643 -11.116 74.151  1.00 95.09  ? 310 ARG B O   1 
ATOM 4909  C CB  . ARG B 1 310 ? -32.683 -9.356  76.338  1.00 107.62 ? 310 ARG B CB  1 
ATOM 4910  C CG  . ARG B 1 310 ? -32.844 -8.544  77.615  1.00 108.24 ? 310 ARG B CG  1 
ATOM 4911  C CD  . ARG B 1 310 ? -34.298 -8.233  77.916  1.00 110.45 ? 310 ARG B CD  1 
ATOM 4912  N NE  . ARG B 1 310 ? -34.850 -9.062  78.976  1.00 108.87 ? 310 ARG B NE  1 
ATOM 4913  C CZ  . ARG B 1 310 ? -35.913 -9.847  78.841  1.00 110.69 ? 310 ARG B CZ  1 
ATOM 4914  N NH1 . ARG B 1 310 ? -36.546 -9.914  77.682  1.00 111.35 ? 310 ARG B NH1 1 
ATOM 4915  N NH2 . ARG B 1 310 ? -36.341 -10.565 79.863  1.00 103.18 ? 310 ARG B NH2 1 
ATOM 4916  N N   . GLY B 1 311 ? -34.445 -12.326 74.837  1.00 98.25  ? 311 GLY B N   1 
ATOM 4917  C CA  . GLY B 1 311 ? -34.576 -13.074 73.575  1.00 93.90  ? 311 GLY B CA  1 
ATOM 4918  C C   . GLY B 1 311 ? -36.023 -13.358 73.237  1.00 95.59  ? 311 GLY B C   1 
ATOM 4919  O O   . GLY B 1 311 ? -36.885 -13.057 74.072  1.00 93.66  ? 311 GLY B O   1 
ATOM 4920  N N   . LEU B 1 312 ? -36.276 -13.926 72.056  1.00 90.95  ? 312 LEU B N   1 
ATOM 4921  C CA  . LEU B 1 312 ? -37.656 -14.276 71.636  1.00 93.19  ? 312 LEU B CA  1 
ATOM 4922  C C   . LEU B 1 312 ? -37.626 -15.570 70.822  1.00 95.23  ? 312 LEU B C   1 
ATOM 4923  O O   . LEU B 1 312 ? -36.949 -15.592 69.793  1.00 99.42  ? 312 LEU B O   1 
ATOM 4924  C CB  . LEU B 1 312 ? -38.222 -13.121 70.807  1.00 91.70  ? 312 LEU B CB  1 
ATOM 4925  C CG  . LEU B 1 312 ? -39.661 -13.273 70.320  1.00 87.71  ? 312 LEU B CG  1 
ATOM 4926  C CD1 . LEU B 1 312 ? -40.570 -13.753 71.439  1.00 91.08  ? 312 LEU B CD1 1 
ATOM 4927  C CD2 . LEU B 1 312 ? -40.170 -11.960 69.753  1.00 95.77  ? 312 LEU B CD2 1 
ATOM 4928  N N   . VAL B 1 313 ? -38.346 -16.597 71.269  1.00 94.02  ? 313 VAL B N   1 
ATOM 4929  C CA  . VAL B 1 313 ? -38.414 -17.852 70.528  1.00 92.26  ? 313 VAL B CA  1 
ATOM 4930  C C   . VAL B 1 313 ? -39.690 -17.865 69.701  1.00 96.59  ? 313 VAL B C   1 
ATOM 4931  O O   . VAL B 1 313 ? -40.752 -17.422 70.159  1.00 98.89  ? 313 VAL B O   1 
ATOM 4932  C CB  . VAL B 1 313 ? -38.349 -19.069 71.472  1.00 92.00  ? 313 VAL B CB  1 
ATOM 4933  C CG1 . VAL B 1 313 ? -36.977 -19.161 72.122  1.00 88.90  ? 313 VAL B CG1 1 
ATOM 4934  C CG2 . VAL B 1 313 ? -39.437 -18.986 72.534  1.00 103.70 ? 313 VAL B CG2 1 
ATOM 4935  N N   . VAL B 1 314 ? -39.588 -18.363 68.471  1.00 98.48  ? 314 VAL B N   1 
ATOM 4936  C CA  . VAL B 1 314 ? -40.708 -18.419 67.541  1.00 103.78 ? 314 VAL B CA  1 
ATOM 4937  C C   . VAL B 1 314 ? -40.899 -19.865 67.100  1.00 105.77 ? 314 VAL B C   1 
ATOM 4938  O O   . VAL B 1 314 ? -39.925 -20.612 66.958  1.00 99.66  ? 314 VAL B O   1 
ATOM 4939  C CB  . VAL B 1 314 ? -40.483 -17.500 66.320  1.00 105.71 ? 314 VAL B CB  1 
ATOM 4940  C CG1 . VAL B 1 314 ? -41.770 -17.344 65.520  1.00 101.81 ? 314 VAL B CG1 1 
ATOM 4941  C CG2 . VAL B 1 314 ? -39.956 -16.141 66.765  1.00 94.45  ? 314 VAL B CG2 1 
ATOM 4942  N N   . GLU B 1 315 ? -42.155 -20.254 66.884  1.00 106.58 ? 315 GLU B N   1 
ATOM 4943  C CA  . GLU B 1 315 ? -42.477 -21.620 66.492  1.00 106.01 ? 315 GLU B CA  1 
ATOM 4944  C C   . GLU B 1 315 ? -42.132 -21.879 65.032  1.00 107.50 ? 315 GLU B C   1 
ATOM 4945  O O   . GLU B 1 315 ? -41.180 -22.609 64.732  1.00 109.62 ? 315 GLU B O   1 
ATOM 4946  C CB  . GLU B 1 315 ? -43.959 -21.912 66.739  1.00 115.41 ? 315 GLU B CB  1 
ATOM 4947  C CG  . GLU B 1 315 ? -44.401 -23.299 66.293  1.00 123.86 ? 315 GLU B CG  1 
ATOM 4948  C CD  . GLU B 1 315 ? -45.521 -23.256 65.269  1.00 115.73 ? 315 GLU B CD  1 
ATOM 4949  O OE1 . GLU B 1 315 ? -46.178 -22.202 65.148  1.00 120.36 ? 315 GLU B OE1 1 
ATOM 4950  O OE2 . GLU B 1 315 ? -45.741 -24.277 64.583  1.00 99.72  ? 315 GLU B OE2 1 
ATOM 4951  N N   . GLY B 1 316 ? -42.895 -21.286 64.117  1.00 106.91 ? 316 GLY B N   1 
ATOM 4952  C CA  . GLY B 1 316 ? -42.746 -21.574 62.704  1.00 101.05 ? 316 GLY B CA  1 
ATOM 4953  C C   . GLY B 1 316 ? -41.934 -20.561 61.926  1.00 98.03  ? 316 GLY B C   1 
ATOM 4954  O O   . GLY B 1 316 ? -40.787 -20.271 62.280  1.00 91.11  ? 316 GLY B O   1 
ATOM 4955  N N   . TRP B 1 317 ? -42.518 -20.020 60.860  1.00 106.06 ? 317 TRP B N   1 
ATOM 4956  C CA  . TRP B 1 317 ? -41.792 -19.120 59.976  1.00 108.15 ? 317 TRP B CA  1 
ATOM 4957  C C   . TRP B 1 317 ? -41.471 -17.808 60.682  1.00 103.43 ? 317 TRP B C   1 
ATOM 4958  O O   . TRP B 1 317 ? -42.297 -17.254 61.413  1.00 102.69 ? 317 TRP B O   1 
ATOM 4959  C CB  . TRP B 1 317 ? -42.600 -18.851 58.706  1.00 108.10 ? 317 TRP B CB  1 
ATOM 4960  C CG  . TRP B 1 317 ? -42.832 -20.071 57.863  1.00 126.16 ? 317 TRP B CG  1 
ATOM 4961  C CD1 . TRP B 1 317 ? -41.882 -20.857 57.277  1.00 130.05 ? 317 TRP B CD1 1 
ATOM 4962  C CD2 . TRP B 1 317 ? -44.099 -20.640 57.497  1.00 129.46 ? 317 TRP B CD2 1 
ATOM 4963  N NE1 . TRP B 1 317 ? -42.474 -21.881 56.580  1.00 122.60 ? 317 TRP B NE1 1 
ATOM 4964  C CE2 . TRP B 1 317 ? -43.834 -21.770 56.698  1.00 123.18 ? 317 TRP B CE2 1 
ATOM 4965  C CE3 . TRP B 1 317 ? -45.428 -20.303 57.773  1.00 128.19 ? 317 TRP B CE3 1 
ATOM 4966  C CZ2 . TRP B 1 317 ? -44.849 -22.565 56.171  1.00 127.30 ? 317 TRP B CZ2 1 
ATOM 4967  C CZ3 . TRP B 1 317 ? -46.435 -21.096 57.247  1.00 126.77 ? 317 TRP B CZ3 1 
ATOM 4968  C CH2 . TRP B 1 317 ? -46.141 -22.213 56.457  1.00 131.37 ? 317 TRP B CH2 1 
ATOM 4969  N N   . ALA B 1 318 ? -40.257 -17.312 60.453  1.00 94.62  ? 318 ALA B N   1 
ATOM 4970  C CA  . ALA B 1 318 ? -39.765 -16.083 61.045  1.00 88.77  ? 318 ALA B CA  1 
ATOM 4971  C C   . ALA B 1 318 ? -39.359 -15.097 59.955  1.00 83.27  ? 318 ALA B C   1 
ATOM 4972  O O   . ALA B 1 318 ? -38.986 -15.508 58.851  1.00 81.74  ? 318 ALA B O   1 
ATOM 4973  C CB  . ALA B 1 318 ? -38.564 -16.350 61.962  1.00 87.71  ? 318 ALA B CB  1 
ATOM 4974  N N   . PRO B 1 319 ? -39.422 -13.793 60.231  1.00 81.55  ? 319 PRO B N   1 
ATOM 4975  C CA  . PRO B 1 319 ? -39.007 -12.808 59.225  1.00 83.27  ? 319 PRO B CA  1 
ATOM 4976  C C   . PRO B 1 319 ? -37.500 -12.807 59.025  1.00 80.66  ? 319 PRO B C   1 
ATOM 4977  O O   . PRO B 1 319 ? -36.826 -11.846 59.403  1.00 72.77  ? 319 PRO B O   1 
ATOM 4978  C CB  . PRO B 1 319 ? -39.492 -11.473 59.807  1.00 88.90  ? 319 PRO B CB  1 
ATOM 4979  C CG  . PRO B 1 319 ? -40.396 -11.831 60.946  1.00 84.10  ? 319 PRO B CG  1 
ATOM 4980  C CD  . PRO B 1 319 ? -39.935 -13.150 61.449  1.00 81.56  ? 319 PRO B CD  1 
ATOM 4981  N N   . GLN B 1 320 ? -36.969 -13.879 58.433  1.00 79.49  ? 320 GLN B N   1 
ATOM 4982  C CA  . GLN B 1 320 ? -35.522 -14.022 58.299  1.00 67.20  ? 320 GLN B CA  1 
ATOM 4983  C C   . GLN B 1 320 ? -34.922 -12.853 57.528  1.00 69.62  ? 320 GLN B C   1 
ATOM 4984  O O   . GLN B 1 320 ? -33.992 -12.191 58.006  1.00 66.98  ? 320 GLN B O   1 
ATOM 4985  C CB  . GLN B 1 320 ? -35.193 -15.347 57.615  1.00 66.28  ? 320 GLN B CB  1 
ATOM 4986  C CG  . GLN B 1 320 ? -33.723 -15.719 57.643  1.00 67.82  ? 320 GLN B CG  1 
ATOM 4987  C CD  . GLN B 1 320 ? -33.450 -17.042 56.959  1.00 75.74  ? 320 GLN B CD  1 
ATOM 4988  O OE1 . GLN B 1 320 ? -34.081 -17.377 55.953  1.00 73.37  ? 320 GLN B OE1 1 
ATOM 4989  N NE2 . GLN B 1 320 ? -32.507 -17.807 57.504  1.00 76.77  ? 320 GLN B NE2 1 
ATOM 4990  N N   . ALA B 1 321 ? -35.450 -12.581 56.334  1.00 73.94  ? 321 ALA B N   1 
ATOM 4991  C CA  . ALA B 1 321 ? -34.947 -11.460 55.545  1.00 74.10  ? 321 ALA B CA  1 
ATOM 4992  C C   . ALA B 1 321 ? -35.193 -10.134 56.253  1.00 70.04  ? 321 ALA B C   1 
ATOM 4993  O O   . ALA B 1 321 ? -34.343 -9.235  56.213  1.00 65.83  ? 321 ALA B O   1 
ATOM 4994  C CB  . ALA B 1 321 ? -35.595 -11.458 54.162  1.00 72.17  ? 321 ALA B CB  1 
ATOM 4995  N N   . ARG B 1 322 ? -36.344 -9.994  56.913  1.00 75.77  ? 322 ARG B N   1 
ATOM 4996  C CA  . ARG B 1 322 ? -36.682 -8.743  57.586  1.00 82.81  ? 322 ARG B CA  1 
ATOM 4997  C C   . ARG B 1 322 ? -35.901 -8.556  58.879  1.00 75.91  ? 322 ARG B C   1 
ATOM 4998  O O   . ARG B 1 322 ? -35.681 -7.416  59.303  1.00 73.48  ? 322 ARG B O   1 
ATOM 4999  C CB  . ARG B 1 322 ? -38.186 -8.690  57.859  1.00 79.93  ? 322 ARG B CB  1 
ATOM 5000  C CG  . ARG B 1 322 ? -39.037 -9.138  56.676  1.00 92.13  ? 322 ARG B CG  1 
ATOM 5001  C CD  . ARG B 1 322 ? -40.527 -8.943  56.928  1.00 98.04  ? 322 ARG B CD  1 
ATOM 5002  N NE  . ARG B 1 322 ? -41.008 -7.659  56.435  1.00 109.04 ? 322 ARG B NE  1 
ATOM 5003  C CZ  . ARG B 1 322 ? -41.049 -6.542  57.150  1.00 117.45 ? 322 ARG B CZ  1 
ATOM 5004  N NH1 . ARG B 1 322 ? -40.646 -6.512  58.410  1.00 120.26 ? 322 ARG B NH1 1 
ATOM 5005  N NH2 . ARG B 1 322 ? -41.510 -5.426  56.589  1.00 115.54 ? 322 ARG B NH2 1 
ATOM 5006  N N   . ILE B 1 323 ? -35.474 -9.647  59.519  1.00 72.31  ? 323 ILE B N   1 
ATOM 5007  C CA  . ILE B 1 323 ? -34.642 -9.523  60.710  1.00 69.98  ? 323 ILE B CA  1 
ATOM 5008  C C   . ILE B 1 323 ? -33.195 -9.239  60.328  1.00 71.31  ? 323 ILE B C   1 
ATOM 5009  O O   . ILE B 1 323 ? -32.540 -8.377  60.927  1.00 64.93  ? 323 ILE B O   1 
ATOM 5010  C CB  . ILE B 1 323 ? -34.761 -10.785 61.585  1.00 65.99  ? 323 ILE B CB  1 
ATOM 5011  C CG1 . ILE B 1 323 ? -36.128 -10.830 62.267  1.00 71.57  ? 323 ILE B CG1 1 
ATOM 5012  C CG2 . ILE B 1 323 ? -33.650 -10.832 62.619  1.00 62.13  ? 323 ILE B CG2 1 
ATOM 5013  C CD1 . ILE B 1 323 ? -36.350 -12.075 63.088  1.00 78.73  ? 323 ILE B CD1 1 
ATOM 5014  N N   . LEU B 1 324 ? -32.672 -9.954  59.327  1.00 69.44  ? 324 LEU B N   1 
ATOM 5015  C CA  . LEU B 1 324 ? -31.313 -9.688  58.870  1.00 61.18  ? 324 LEU B CA  1 
ATOM 5016  C C   . LEU B 1 324 ? -31.190 -8.295  58.268  1.00 62.63  ? 324 LEU B C   1 
ATOM 5017  O O   . LEU B 1 324 ? -30.144 -7.650  58.401  1.00 64.54  ? 324 LEU B O   1 
ATOM 5018  C CB  . LEU B 1 324 ? -30.880 -10.749 57.858  1.00 62.64  ? 324 LEU B CB  1 
ATOM 5019  C CG  . LEU B 1 324 ? -30.750 -12.182 58.376  1.00 67.95  ? 324 LEU B CG  1 
ATOM 5020  C CD1 . LEU B 1 324 ? -30.273 -13.102 57.264  1.00 68.29  ? 324 LEU B CD1 1 
ATOM 5021  C CD2 . LEU B 1 324 ? -29.811 -12.244 59.571  1.00 62.61  ? 324 LEU B CD2 1 
ATOM 5022  N N   . GLY B 1 325 ? -32.250 -7.807  57.614  1.00 66.59  ? 325 GLY B N   1 
ATOM 5023  C CA  . GLY B 1 325 ? -32.230 -6.460  57.077  1.00 64.51  ? 325 GLY B CA  1 
ATOM 5024  C C   . GLY B 1 325 ? -32.428 -5.372  58.106  1.00 63.58  ? 325 GLY B C   1 
ATOM 5025  O O   . GLY B 1 325 ? -32.117 -4.210  57.830  1.00 61.73  ? 325 GLY B O   1 
ATOM 5026  N N   . HIS B 1 326 ? -32.925 -5.719  59.289  1.00 73.68  ? 326 HIS B N   1 
ATOM 5027  C CA  . HIS B 1 326 ? -33.109 -4.722  60.334  1.00 71.35  ? 326 HIS B CA  1 
ATOM 5028  C C   . HIS B 1 326 ? -31.760 -4.303  60.904  1.00 65.42  ? 326 HIS B C   1 
ATOM 5029  O O   . HIS B 1 326 ? -30.831 -5.108  61.007  1.00 67.02  ? 326 HIS B O   1 
ATOM 5030  C CB  . HIS B 1 326 ? -34.016 -5.268  61.439  1.00 64.97  ? 326 HIS B CB  1 
ATOM 5031  C CG  . HIS B 1 326 ? -34.526 -4.223  62.378  1.00 77.59  ? 326 HIS B CG  1 
ATOM 5032  N ND1 . HIS B 1 326 ? -33.910 -3.940  63.577  1.00 81.79  ? 326 HIS B ND1 1 
ATOM 5033  C CD2 . HIS B 1 326 ? -35.591 -3.391  62.296  1.00 76.92  ? 326 HIS B CD2 1 
ATOM 5034  C CE1 . HIS B 1 326 ? -34.574 -2.979  64.196  1.00 80.70  ? 326 HIS B CE1 1 
ATOM 5035  N NE2 . HIS B 1 326 ? -35.598 -2.628  63.439  1.00 73.68  ? 326 HIS B NE2 1 
ATOM 5036  N N   . SER B 1 327 ? -31.656 -3.026  61.274  1.00 68.65  ? 327 SER B N   1 
ATOM 5037  C CA  . SER B 1 327 ? -30.372 -2.482  61.702  1.00 77.95  ? 327 SER B CA  1 
ATOM 5038  C C   . SER B 1 327 ? -29.943 -2.993  63.071  1.00 79.94  ? 327 SER B C   1 
ATOM 5039  O O   . SER B 1 327 ? -28.763 -2.874  63.418  1.00 79.32  ? 327 SER B O   1 
ATOM 5040  C CB  . SER B 1 327 ? -30.427 -0.955  61.715  1.00 87.86  ? 327 SER B CB  1 
ATOM 5041  O OG  . SER B 1 327 ? -31.487 -0.487  62.532  1.00 96.66  ? 327 SER B OG  1 
ATOM 5042  N N   . SER B 1 328 ? -30.864 -3.554  63.857  1.00 75.11  ? 328 SER B N   1 
ATOM 5043  C CA  . SER B 1 328 ? -30.528 -4.031  65.193  1.00 76.09  ? 328 SER B CA  1 
ATOM 5044  C C   . SER B 1 328 ? -29.840 -5.389  65.188  1.00 72.58  ? 328 SER B C   1 
ATOM 5045  O O   . SER B 1 328 ? -29.335 -5.812  66.235  1.00 75.94  ? 328 SER B O   1 
ATOM 5046  C CB  . SER B 1 328 ? -31.786 -4.100  66.061  1.00 78.96  ? 328 SER B CB  1 
ATOM 5047  O OG  . SER B 1 328 ? -32.309 -2.807  66.301  1.00 86.27  ? 328 SER B OG  1 
ATOM 5048  N N   . THR B 1 329 ? -29.806 -6.079  64.053  1.00 66.60  ? 329 THR B N   1 
ATOM 5049  C CA  . THR B 1 329 ? -29.196 -7.395  63.974  1.00 68.10  ? 329 THR B CA  1 
ATOM 5050  C C   . THR B 1 329 ? -27.733 -7.264  63.569  1.00 72.95  ? 329 THR B C   1 
ATOM 5051  O O   . THR B 1 329 ? -27.405 -6.592  62.585  1.00 72.61  ? 329 THR B O   1 
ATOM 5052  C CB  . THR B 1 329 ? -29.944 -8.283  62.980  1.00 66.61  ? 329 THR B CB  1 
ATOM 5053  O OG1 . THR B 1 329 ? -31.351 -8.192  63.229  1.00 70.85  ? 329 THR B OG1 1 
ATOM 5054  C CG2 . THR B 1 329 ? -29.508 -9.731  63.130  1.00 64.59  ? 329 THR B CG2 1 
ATOM 5055  N N   . GLY B 1 330 ? -26.861 -7.903  64.340  1.00 69.27  ? 330 GLY B N   1 
ATOM 5056  C CA  . GLY B 1 330 ? -25.441 -7.907  64.059  1.00 71.48  ? 330 GLY B CA  1 
ATOM 5057  C C   . GLY B 1 330 ? -24.817 -9.285  64.162  1.00 67.25  ? 330 GLY B C   1 
ATOM 5058  O O   . GLY B 1 330 ? -23.592 -9.413  64.272  1.00 56.93  ? 330 GLY B O   1 
ATOM 5059  N N   . GLY B 1 331 ? -25.655 -10.322 64.127  1.00 62.20  ? 331 GLY B N   1 
ATOM 5060  C CA  . GLY B 1 331 ? -25.203 -11.700 64.209  1.00 59.28  ? 331 GLY B CA  1 
ATOM 5061  C C   . GLY B 1 331 ? -26.245 -12.691 63.727  1.00 58.06  ? 331 GLY B C   1 
ATOM 5062  O O   . GLY B 1 331 ? -27.447 -12.487 63.929  1.00 61.87  ? 331 GLY B O   1 
ATOM 5063  N N   . PHE B 1 332 ? -25.796 -13.771 63.083  1.00 56.10  ? 332 PHE B N   1 
ATOM 5064  C CA  . PHE B 1 332 ? -26.707 -14.765 62.504  1.00 54.29  ? 332 PHE B CA  1 
ATOM 5065  C C   . PHE B 1 332 ? -26.143 -16.156 62.776  1.00 56.28  ? 332 PHE B C   1 
ATOM 5066  O O   . PHE B 1 332 ? -25.268 -16.628 62.045  1.00 56.03  ? 332 PHE B O   1 
ATOM 5067  C CB  . PHE B 1 332 ? -26.901 -14.525 61.008  1.00 54.40  ? 332 PHE B CB  1 
ATOM 5068  C CG  . PHE B 1 332 ? -27.895 -15.458 60.339  1.00 61.52  ? 332 PHE B CG  1 
ATOM 5069  C CD1 . PHE B 1 332 ? -28.736 -16.283 61.077  1.00 57.99  ? 332 PHE B CD1 1 
ATOM 5070  C CD2 . PHE B 1 332 ? -27.980 -15.506 58.957  1.00 57.87  ? 332 PHE B CD2 1 
ATOM 5071  C CE1 . PHE B 1 332 ? -29.636 -17.139 60.441  1.00 62.89  ? 332 PHE B CE1 1 
ATOM 5072  C CE2 . PHE B 1 332 ? -28.878 -16.357 58.319  1.00 50.75  ? 332 PHE B CE2 1 
ATOM 5073  C CZ  . PHE B 1 332 ? -29.706 -17.170 59.060  1.00 59.09  ? 332 PHE B CZ  1 
ATOM 5074  N N   . VAL B 1 333 ? -26.658 -16.814 63.810  1.00 63.36  ? 333 VAL B N   1 
ATOM 5075  C CA  . VAL B 1 333 ? -26.319 -18.206 64.090  1.00 60.27  ? 333 VAL B CA  1 
ATOM 5076  C C   . VAL B 1 333 ? -27.115 -19.076 63.121  1.00 61.72  ? 333 VAL B C   1 
ATOM 5077  O O   . VAL B 1 333 ? -28.343 -19.157 63.214  1.00 61.24  ? 333 VAL B O   1 
ATOM 5078  C CB  . VAL B 1 333 ? -26.617 -18.583 65.545  1.00 56.59  ? 333 VAL B CB  1 
ATOM 5079  C CG1 . VAL B 1 333 ? -26.294 -20.051 65.790  1.00 62.27  ? 333 VAL B CG1 1 
ATOM 5080  C CG2 . VAL B 1 333 ? -25.824 -17.701 66.493  1.00 64.04  ? 333 VAL B CG2 1 
ATOM 5081  N N   . SER B 1 334 ? -26.423 -19.729 62.191  1.00 63.20  ? 334 SER B N   1 
ATOM 5082  C CA  . SER B 1 334 ? -27.092 -20.411 61.097  1.00 50.14  ? 334 SER B CA  1 
ATOM 5083  C C   . SER B 1 334 ? -26.516 -21.805 60.893  1.00 52.70  ? 334 SER B C   1 
ATOM 5084  O O   . SER B 1 334 ? -25.379 -22.096 61.267  1.00 62.61  ? 334 SER B O   1 
ATOM 5085  C CB  . SER B 1 334 ? -26.980 -19.611 59.792  1.00 48.40  ? 334 SER B CB  1 
ATOM 5086  O OG  . SER B 1 334 ? -27.488 -20.351 58.698  1.00 56.16  ? 334 SER B OG  1 
ATOM 5087  N N   . HIS B 1 335 ? -27.330 -22.668 60.285  1.00 57.08  ? 335 HIS B N   1 
ATOM 5088  C CA  . HIS B 1 335 ? -26.880 -23.991 59.870  1.00 54.55  ? 335 HIS B CA  1 
ATOM 5089  C C   . HIS B 1 335 ? -26.150 -23.963 58.536  1.00 55.80  ? 335 HIS B C   1 
ATOM 5090  O O   . HIS B 1 335 ? -25.796 -25.031 58.024  1.00 62.73  ? 335 HIS B O   1 
ATOM 5091  C CB  . HIS B 1 335 ? -28.068 -24.955 59.791  1.00 63.27  ? 335 HIS B CB  1 
ATOM 5092  C CG  . HIS B 1 335 ? -28.950 -24.738 58.599  1.00 68.36  ? 335 HIS B CG  1 
ATOM 5093  N ND1 . HIS B 1 335 ? -29.670 -23.578 58.408  1.00 65.49  ? 335 HIS B ND1 1 
ATOM 5094  C CD2 . HIS B 1 335 ? -29.236 -25.539 57.545  1.00 70.05  ? 335 HIS B CD2 1 
ATOM 5095  C CE1 . HIS B 1 335 ? -30.356 -23.671 57.281  1.00 64.50  ? 335 HIS B CE1 1 
ATOM 5096  N NE2 . HIS B 1 335 ? -30.113 -24.851 56.739  1.00 62.61  ? 335 HIS B NE2 1 
ATOM 5097  N N   . CYS B 1 336 ? -25.932 -22.774 57.968  1.00 55.57  ? 336 CYS B N   1 
ATOM 5098  C CA  . CYS B 1 336 ? -25.123 -22.579 56.761  1.00 51.30  ? 336 CYS B CA  1 
ATOM 5099  C C   . CYS B 1 336 ? -25.790 -23.180 55.522  1.00 48.02  ? 336 CYS B C   1 
ATOM 5100  O O   . CYS B 1 336 ? -25.166 -23.892 54.739  1.00 49.50  ? 336 CYS B O   1 
ATOM 5101  C CB  . CYS B 1 336 ? -23.707 -23.131 56.945  1.00 45.84  ? 336 CYS B CB  1 
ATOM 5102  S SG  . CYS B 1 336 ? -22.723 -22.190 58.112  1.00 46.31  ? 336 CYS B SG  1 
ATOM 5103  N N   . GLY B 1 337 ? -27.075 -22.883 55.354  1.00 47.10  ? 337 GLY B N   1 
ATOM 5104  C CA  . GLY B 1 337 ? -27.697 -23.069 54.060  1.00 46.45  ? 337 GLY B CA  1 
ATOM 5105  C C   . GLY B 1 337 ? -27.238 -22.000 53.086  1.00 50.34  ? 337 GLY B C   1 
ATOM 5106  O O   . GLY B 1 337 ? -26.890 -20.883 53.471  1.00 48.91  ? 337 GLY B O   1 
ATOM 5107  N N   . TRP B 1 338 ? -27.224 -22.349 51.800  1.00 43.08  ? 338 TRP B N   1 
ATOM 5108  C CA  . TRP B 1 338 ? -26.693 -21.423 50.805  1.00 39.18  ? 338 TRP B CA  1 
ATOM 5109  C C   . TRP B 1 338 ? -27.533 -20.155 50.730  1.00 34.39  ? 338 TRP B C   1 
ATOM 5110  O O   . TRP B 1 338 ? -26.996 -19.041 50.709  1.00 44.06  ? 338 TRP B O   1 
ATOM 5111  C CB  . TRP B 1 338 ? -26.602 -22.101 49.439  1.00 39.03  ? 338 TRP B CB  1 
ATOM 5112  C CG  . TRP B 1 338 ? -25.862 -21.280 48.425  1.00 39.08  ? 338 TRP B CG  1 
ATOM 5113  C CD1 . TRP B 1 338 ? -26.319 -20.878 47.205  1.00 38.87  ? 338 TRP B CD1 1 
ATOM 5114  C CD2 . TRP B 1 338 ? -24.535 -20.746 48.550  1.00 48.48  ? 338 TRP B CD2 1 
ATOM 5115  N NE1 . TRP B 1 338 ? -25.360 -20.142 46.558  1.00 43.34  ? 338 TRP B NE1 1 
ATOM 5116  C CE2 . TRP B 1 338 ? -24.256 -20.043 47.362  1.00 45.85  ? 338 TRP B CE2 1 
ATOM 5117  C CE3 . TRP B 1 338 ? -23.558 -20.801 49.551  1.00 42.48  ? 338 TRP B CE3 1 
ATOM 5118  C CZ2 . TRP B 1 338 ? -23.039 -19.398 47.146  1.00 50.22  ? 338 TRP B CZ2 1 
ATOM 5119  C CZ3 . TRP B 1 338 ? -22.354 -20.159 49.334  1.00 48.82  ? 338 TRP B CZ3 1 
ATOM 5120  C CH2 . TRP B 1 338 ? -22.103 -19.468 48.143  1.00 49.52  ? 338 TRP B CH2 1 
ATOM 5121  N N   . SER B 1 339 ? -28.860 -20.297 50.686  1.00 33.85  ? 339 SER B N   1 
ATOM 5122  C CA  . SER B 1 339 ? -29.716 -19.113 50.682  1.00 42.08  ? 339 SER B CA  1 
ATOM 5123  C C   . SER B 1 339 ? -29.580 -18.336 51.985  1.00 41.86  ? 339 SER B C   1 
ATOM 5124  O O   . SER B 1 339 ? -29.633 -17.100 51.987  1.00 46.58  ? 339 SER B O   1 
ATOM 5125  C CB  . SER B 1 339 ? -31.172 -19.513 50.442  1.00 31.40  ? 339 SER B CB  1 
ATOM 5126  O OG  . SER B 1 339 ? -31.344 -20.045 49.141  1.00 31.41  ? 339 SER B OG  1 
ATOM 5127  N N   . SER B 1 340 ? -29.385 -19.043 53.099  1.00 40.35  ? 340 SER B N   1 
ATOM 5128  C CA  . SER B 1 340 ? -29.212 -18.371 54.382  1.00 47.19  ? 340 SER B CA  1 
ATOM 5129  C C   . SER B 1 340 ? -27.941 -17.531 54.398  1.00 52.24  ? 340 SER B C   1 
ATOM 5130  O O   . SER B 1 340 ? -27.953 -16.375 54.838  1.00 56.83  ? 340 SER B O   1 
ATOM 5131  C CB  . SER B 1 340 ? -29.200 -19.401 55.509  1.00 48.08  ? 340 SER B CB  1 
ATOM 5132  O OG  . SER B 1 340 ? -30.418 -20.124 55.538  1.00 64.58  ? 340 SER B OG  1 
ATOM 5133  N N   . ILE B 1 341 ? -26.831 -18.092 53.908  1.00 49.40  ? 341 ILE B N   1 
ATOM 5134  C CA  . ILE B 1 341 ? -25.576 -17.346 53.871  1.00 41.99  ? 341 ILE B CA  1 
ATOM 5135  C C   . ILE B 1 341 ? -25.672 -16.180 52.893  1.00 47.88  ? 341 ILE B C   1 
ATOM 5136  O O   . ILE B 1 341 ? -25.167 -15.082 53.164  1.00 57.16  ? 341 ILE B O   1 
ATOM 5137  C CB  . ILE B 1 341 ? -24.411 -18.290 53.526  1.00 42.73  ? 341 ILE B CB  1 
ATOM 5138  C CG1 . ILE B 1 341 ? -24.171 -19.266 54.681  1.00 47.69  ? 341 ILE B CG1 1 
ATOM 5139  C CG2 . ILE B 1 341 ? -23.149 -17.499 53.212  1.00 46.35  ? 341 ILE B CG2 1 
ATOM 5140  C CD1 . ILE B 1 341 ? -22.995 -20.191 54.466  1.00 51.86  ? 341 ILE B CD1 1 
ATOM 5141  N N   . ALA B 1 342 ? -26.324 -16.391 51.749  1.00 51.64  ? 342 ALA B N   1 
ATOM 5142  C CA  . ALA B 1 342 ? -26.507 -15.300 50.798  1.00 54.66  ? 342 ALA B CA  1 
ATOM 5143  C C   . ALA B 1 342 ? -27.303 -14.157 51.419  1.00 59.50  ? 342 ALA B C   1 
ATOM 5144  O O   . ALA B 1 342 ? -26.932 -12.986 51.277  1.00 66.66  ? 342 ALA B O   1 
ATOM 5145  C CB  . ALA B 1 342 ? -27.194 -15.813 49.531  1.00 52.51  ? 342 ALA B CB  1 
ATOM 5146  N N   . GLU B 1 343 ? -28.397 -14.479 52.114  1.00 55.29  ? 343 GLU B N   1 
ATOM 5147  C CA  . GLU B 1 343 ? -29.186 -13.435 52.766  1.00 60.22  ? 343 GLU B CA  1 
ATOM 5148  C C   . GLU B 1 343 ? -28.394 -12.747 53.868  1.00 66.75  ? 343 GLU B C   1 
ATOM 5149  O O   . GLU B 1 343 ? -28.502 -11.529 54.053  1.00 66.23  ? 343 GLU B O   1 
ATOM 5150  C CB  . GLU B 1 343 ? -30.478 -14.022 53.332  1.00 59.33  ? 343 GLU B CB  1 
ATOM 5151  C CG  . GLU B 1 343 ? -31.544 -14.317 52.300  1.00 55.72  ? 343 GLU B CG  1 
ATOM 5152  C CD  . GLU B 1 343 ? -32.869 -14.674 52.940  1.00 69.17  ? 343 GLU B CD  1 
ATOM 5153  O OE1 . GLU B 1 343 ? -32.861 -15.093 54.116  1.00 76.59  ? 343 GLU B OE1 1 
ATOM 5154  O OE2 . GLU B 1 343 ? -33.915 -14.525 52.275  1.00 85.33  ? 343 GLU B OE2 1 
ATOM 5155  N N   . SER B 1 344 ? -27.596 -13.511 54.618  1.00 66.29  ? 344 SER B N   1 
ATOM 5156  C CA  . SER B 1 344 ? -26.779 -12.909 55.667  1.00 62.05  ? 344 SER B CA  1 
ATOM 5157  C C   . SER B 1 344 ? -25.739 -11.964 55.087  1.00 60.71  ? 344 SER B C   1 
ATOM 5158  O O   . SER B 1 344 ? -25.390 -10.961 55.722  1.00 61.84  ? 344 SER B O   1 
ATOM 5159  C CB  . SER B 1 344 ? -26.100 -13.994 56.498  1.00 55.10  ? 344 SER B CB  1 
ATOM 5160  O OG  . SER B 1 344 ? -25.476 -13.440 57.643  1.00 62.62  ? 344 SER B OG  1 
ATOM 5161  N N   . MET B 1 345 ? -25.231 -12.258 53.894  1.00 59.39  ? 345 MET B N   1 
ATOM 5162  C CA  . MET B 1 345 ? -24.216 -11.398 53.299  1.00 64.44  ? 345 MET B CA  1 
ATOM 5163  C C   . MET B 1 345 ? -24.803 -10.215 52.541  1.00 64.84  ? 345 MET B C   1 
ATOM 5164  O O   . MET B 1 345 ? -24.132 -9.184  52.410  1.00 67.81  ? 345 MET B O   1 
ATOM 5165  C CB  . MET B 1 345 ? -23.309 -12.213 52.373  1.00 60.01  ? 345 MET B CB  1 
ATOM 5166  C CG  . MET B 1 345 ? -22.504 -13.267 53.107  1.00 47.17  ? 345 MET B CG  1 
ATOM 5167  S SD  . MET B 1 345 ? -21.109 -13.852 52.139  1.00 63.59  ? 345 MET B SD  1 
ATOM 5168  C CE  . MET B 1 345 ? -20.178 -12.332 51.959  1.00 72.07  ? 345 MET B CE  1 
ATOM 5169  N N   . LYS B 1 346 ? -26.037 -10.325 52.042  1.00 59.14  ? 346 LYS B N   1 
ATOM 5170  C CA  . LYS B 1 346 ? -26.650 -9.178  51.381  1.00 59.52  ? 346 LYS B CA  1 
ATOM 5171  C C   . LYS B 1 346 ? -26.995 -8.069  52.366  1.00 63.21  ? 346 LYS B C   1 
ATOM 5172  O O   . LYS B 1 346 ? -27.102 -6.907  51.961  1.00 64.06  ? 346 LYS B O   1 
ATOM 5173  C CB  . LYS B 1 346 ? -27.907 -9.599  50.615  1.00 56.06  ? 346 LYS B CB  1 
ATOM 5174  C CG  . LYS B 1 346 ? -28.415 -8.541  49.637  1.00 51.02  ? 346 LYS B CG  1 
ATOM 5175  C CD  . LYS B 1 346 ? -29.865 -8.776  49.250  1.00 58.64  ? 346 LYS B CD  1 
ATOM 5176  C CE  . LYS B 1 346 ? -30.364 -7.692  48.305  1.00 72.17  ? 346 LYS B CE  1 
ATOM 5177  N NZ  . LYS B 1 346 ? -30.230 -6.333  48.902  1.00 84.85  ? 346 LYS B NZ  1 
ATOM 5178  N N   . PHE B 1 347 ? -27.155 -8.395  53.649  1.00 65.33  ? 347 PHE B N   1 
ATOM 5179  C CA  . PHE B 1 347 ? -27.489 -7.412  54.668  1.00 63.65  ? 347 PHE B CA  1 
ATOM 5180  C C   . PHE B 1 347 ? -26.334 -7.145  55.630  1.00 63.03  ? 347 PHE B C   1 
ATOM 5181  O O   . PHE B 1 347 ? -26.529 -6.458  56.639  1.00 66.57  ? 347 PHE B O   1 
ATOM 5182  C CB  . PHE B 1 347 ? -28.735 -7.855  55.439  1.00 55.92  ? 347 PHE B CB  1 
ATOM 5183  C CG  . PHE B 1 347 ? -29.957 -8.004  54.577  1.00 59.97  ? 347 PHE B CG  1 
ATOM 5184  C CD1 . PHE B 1 347 ? -30.563 -6.892  54.013  1.00 62.03  ? 347 PHE B CD1 1 
ATOM 5185  C CD2 . PHE B 1 347 ? -30.504 -9.252  54.335  1.00 67.01  ? 347 PHE B CD2 1 
ATOM 5186  C CE1 . PHE B 1 347 ? -31.689 -7.026  53.221  1.00 65.12  ? 347 PHE B CE1 1 
ATOM 5187  C CE2 . PHE B 1 347 ? -31.630 -9.391  53.542  1.00 62.24  ? 347 PHE B CE2 1 
ATOM 5188  C CZ  . PHE B 1 347 ? -32.221 -8.276  52.985  1.00 60.13  ? 347 PHE B CZ  1 
ATOM 5189  N N   . GLY B 1 348 ? -25.146 -7.672  55.346  1.00 63.21  ? 348 GLY B N   1 
ATOM 5190  C CA  . GLY B 1 348 ? -23.976 -7.374  56.156  1.00 66.49  ? 348 GLY B CA  1 
ATOM 5191  C C   . GLY B 1 348 ? -23.992 -7.942  57.556  1.00 66.02  ? 348 GLY B C   1 
ATOM 5192  O O   . GLY B 1 348 ? -23.358 -7.374  58.452  1.00 55.10  ? 348 GLY B O   1 
ATOM 5193  N N   . VAL B 1 349 ? -24.692 -9.047  57.774  1.00 60.88  ? 349 VAL B N   1 
ATOM 5194  C CA  . VAL B 1 349 ? -24.773 -9.695  59.078  1.00 53.40  ? 349 VAL B CA  1 
ATOM 5195  C C   . VAL B 1 349 ? -23.749 -10.824 59.109  1.00 52.99  ? 349 VAL B C   1 
ATOM 5196  O O   . VAL B 1 349 ? -23.877 -11.778 58.326  1.00 61.02  ? 349 VAL B O   1 
ATOM 5197  C CB  . VAL B 1 349 ? -26.188 -10.227 59.353  1.00 59.13  ? 349 VAL B CB  1 
ATOM 5198  C CG1 . VAL B 1 349 ? -26.246 -10.921 60.705  1.00 58.44  ? 349 VAL B CG1 1 
ATOM 5199  C CG2 . VAL B 1 349 ? -27.206 -9.097  59.277  1.00 56.51  ? 349 VAL B CG2 1 
ATOM 5200  N N   . PRO B 1 350 ? -22.735 -10.765 59.974  1.00 48.69  ? 350 PRO B N   1 
ATOM 5201  C CA  . PRO B 1 350 ? -21.755 -11.857 60.038  1.00 52.31  ? 350 PRO B CA  1 
ATOM 5202  C C   . PRO B 1 350 ? -22.393 -13.161 60.495  1.00 52.18  ? 350 PRO B C   1 
ATOM 5203  O O   . PRO B 1 350 ? -23.467 -13.183 61.096  1.00 59.31  ? 350 PRO B O   1 
ATOM 5204  C CB  . PRO B 1 350 ? -20.722 -11.352 61.053  1.00 51.40  ? 350 PRO B CB  1 
ATOM 5205  C CG  . PRO B 1 350 ? -21.446 -10.327 61.856  1.00 59.50  ? 350 PRO B CG  1 
ATOM 5206  C CD  . PRO B 1 350 ? -22.410 -9.675  60.910  1.00 59.97  ? 350 PRO B CD  1 
ATOM 5207  N N   . VAL B 1 351 ? -21.707 -14.262 60.200  1.00 48.94  ? 351 VAL B N   1 
ATOM 5208  C CA  . VAL B 1 351 ? -22.279 -15.602 60.298  1.00 53.91  ? 351 VAL B CA  1 
ATOM 5209  C C   . VAL B 1 351 ? -21.617 -16.366 61.437  1.00 63.05  ? 351 VAL B C   1 
ATOM 5210  O O   . VAL B 1 351 ? -20.387 -16.355 61.578  1.00 67.79  ? 351 VAL B O   1 
ATOM 5211  C CB  . VAL B 1 351 ? -22.132 -16.369 58.974  1.00 53.78  ? 351 VAL B CB  1 
ATOM 5212  C CG1 . VAL B 1 351 ? -22.824 -17.720 59.064  1.00 53.36  ? 351 VAL B CG1 1 
ATOM 5213  C CG2 . VAL B 1 351 ? -22.692 -15.551 57.821  1.00 58.55  ? 351 VAL B CG2 1 
ATOM 5214  N N   . ILE B 1 352 ? -22.440 -17.026 62.248  1.00 65.74  ? 352 ILE B N   1 
ATOM 5215  C CA  . ILE B 1 352 ? -21.996 -17.994 63.240  1.00 63.16  ? 352 ILE B CA  1 
ATOM 5216  C C   . ILE B 1 352 ? -22.330 -19.363 62.658  1.00 59.05  ? 352 ILE B C   1 
ATOM 5217  O O   . ILE B 1 352 ? -23.497 -19.775 62.628  1.00 52.04  ? 352 ILE B O   1 
ATOM 5218  C CB  . ILE B 1 352 ? -22.677 -17.772 64.594  1.00 65.35  ? 352 ILE B CB  1 
ATOM 5219  C CG1 . ILE B 1 352 ? -22.705 -16.284 64.947  1.00 55.51  ? 352 ILE B CG1 1 
ATOM 5220  C CG2 . ILE B 1 352 ? -21.976 -18.569 65.682  1.00 51.38  ? 352 ILE B CG2 1 
ATOM 5221  C CD1 . ILE B 1 352 ? -21.341 -15.683 65.143  1.00 66.33  ? 352 ILE B CD1 1 
ATOM 5222  N N   . ALA B 1 353 ? -21.308 -20.067 62.184  1.00 55.39  ? 353 ALA B N   1 
ATOM 5223  C CA  . ALA B 1 353 ? -21.507 -21.316 61.467  1.00 55.23  ? 353 ALA B CA  1 
ATOM 5224  C C   . ALA B 1 353 ? -21.748 -22.461 62.439  1.00 57.07  ? 353 ALA B C   1 
ATOM 5225  O O   . ALA B 1 353 ? -20.943 -22.705 63.346  1.00 65.05  ? 353 ALA B O   1 
ATOM 5226  C CB  . ALA B 1 353 ? -20.301 -21.620 60.580  1.00 58.82  ? 353 ALA B CB  1 
ATOM 5227  N N   . MET B 1 354 ? -22.868 -23.172 62.246  1.00 52.76  ? 354 MET B N   1 
ATOM 5228  C CA  . MET B 1 354 ? -23.214 -24.354 63.023  1.00 59.27  ? 354 MET B CA  1 
ATOM 5229  C C   . MET B 1 354 ? -23.818 -25.381 62.058  1.00 63.32  ? 354 MET B C   1 
ATOM 5230  O O   . MET B 1 354 ? -25.000 -25.714 62.113  1.00 65.30  ? 354 MET B O   1 
ATOM 5231  C CB  . MET B 1 354 ? -24.169 -24.019 64.172  1.00 64.03  ? 354 MET B CB  1 
ATOM 5232  C CG  . MET B 1 354 ? -23.521 -23.231 65.303  1.00 70.67  ? 354 MET B CG  1 
ATOM 5233  S SD  . MET B 1 354 ? -24.586 -23.002 66.742  1.00 64.05  ? 354 MET B SD  1 
ATOM 5234  C CE  . MET B 1 354 ? -25.105 -24.689 67.054  1.00 62.98  ? 354 MET B CE  1 
ATOM 5235  N N   . ALA B 1 355 ? -22.988 -25.886 61.151  1.00 67.20  ? 355 ALA B N   1 
ATOM 5236  C CA  . ALA B 1 355 ? -23.423 -26.852 60.156  1.00 71.15  ? 355 ALA B CA  1 
ATOM 5237  C C   . ALA B 1 355 ? -23.420 -28.263 60.740  1.00 72.95  ? 355 ALA B C   1 
ATOM 5238  O O   . ALA B 1 355 ? -22.938 -28.506 61.849  1.00 74.02  ? 355 ALA B O   1 
ATOM 5239  C CB  . ALA B 1 355 ? -22.526 -26.785 58.924  1.00 61.96  ? 355 ALA B CB  1 
ATOM 5240  N N   . ARG B 1 356 ? -23.973 -29.206 59.975  1.00 72.68  ? 356 ARG B N   1 
ATOM 5241  C CA  . ARG B 1 356 ? -23.986 -30.596 60.420  1.00 80.62  ? 356 ARG B CA  1 
ATOM 5242  C C   . ARG B 1 356 ? -23.943 -31.579 59.255  1.00 70.83  ? 356 ARG B C   1 
ATOM 5243  O O   . ARG B 1 356 ? -23.106 -32.489 59.243  1.00 70.14  ? 356 ARG B O   1 
ATOM 5244  C CB  . ARG B 1 356 ? -25.215 -30.869 61.292  1.00 80.21  ? 356 ARG B CB  1 
ATOM 5245  C CG  . ARG B 1 356 ? -24.888 -31.646 62.563  1.00 83.05  ? 356 ARG B CG  1 
ATOM 5246  C CD  . ARG B 1 356 ? -26.137 -32.034 63.342  1.00 99.30  ? 356 ARG B CD  1 
ATOM 5247  N NE  . ARG B 1 356 ? -26.806 -33.194 62.763  1.00 105.58 ? 356 ARG B NE  1 
ATOM 5248  C CZ  . ARG B 1 356 ? -26.470 -34.453 63.013  1.00 102.61 ? 356 ARG B CZ  1 
ATOM 5249  N NH1 . ARG B 1 356 ? -25.463 -34.753 63.817  1.00 104.91 ? 356 ARG B NH1 1 
ATOM 5250  N NH2 . ARG B 1 356 ? -27.159 -35.435 62.440  1.00 92.20  ? 356 ARG B NH2 1 
ATOM 5251  N N   . HIS B 1 357 ? -24.833 -31.422 58.279  1.00 64.71  ? 357 HIS B N   1 
ATOM 5252  C CA  . HIS B 1 357 ? -24.965 -32.386 57.197  1.00 69.41  ? 357 HIS B CA  1 
ATOM 5253  C C   . HIS B 1 357 ? -25.011 -31.668 55.852  1.00 73.44  ? 357 HIS B C   1 
ATOM 5254  O O   . HIS B 1 357 ? -25.063 -30.438 55.777  1.00 70.45  ? 357 HIS B O   1 
ATOM 5255  C CB  . HIS B 1 357 ? -26.212 -33.263 57.381  1.00 62.85  ? 357 HIS B CB  1 
ATOM 5256  C CG  . HIS B 1 357 ? -27.478 -32.485 57.555  1.00 74.36  ? 357 HIS B CG  1 
ATOM 5257  N ND1 . HIS B 1 357 ? -28.309 -32.166 56.502  1.00 88.21  ? 357 HIS B ND1 1 
ATOM 5258  C CD2 . HIS B 1 357 ? -28.059 -31.962 58.663  1.00 81.21  ? 357 HIS B CD2 1 
ATOM 5259  C CE1 . HIS B 1 357 ? -29.345 -31.481 56.950  1.00 87.55  ? 357 HIS B CE1 1 
ATOM 5260  N NE2 . HIS B 1 357 ? -29.217 -31.344 58.258  1.00 88.07  ? 357 HIS B NE2 1 
ATOM 5261  N N   . LEU B 1 358 ? -24.984 -32.466 54.787  1.00 67.69  ? 358 LEU B N   1 
ATOM 5262  C CA  . LEU B 1 358 ? -25.017 -31.988 53.399  1.00 57.35  ? 358 LEU B CA  1 
ATOM 5263  C C   . LEU B 1 358 ? -23.790 -31.104 53.157  1.00 53.38  ? 358 LEU B C   1 
ATOM 5264  O O   . LEU B 1 358 ? -22.744 -31.284 53.793  1.00 65.21  ? 358 LEU B O   1 
ATOM 5265  C CB  . LEU B 1 358 ? -26.349 -31.317 53.110  1.00 55.68  ? 358 LEU B CB  1 
ATOM 5266  C CG  . LEU B 1 358 ? -27.583 -32.217 53.191  1.00 64.96  ? 358 LEU B CG  1 
ATOM 5267  C CD1 . LEU B 1 358 ? -28.833 -31.474 52.741  1.00 70.47  ? 358 LEU B CD1 1 
ATOM 5268  C CD2 . LEU B 1 358 ? -27.372 -33.475 52.367  1.00 63.06  ? 358 LEU B CD2 1 
ATOM 5269  N N   . ASP B 1 359 ? -23.902 -30.151 52.237  1.00 51.02  ? 359 ASP B N   1 
ATOM 5270  C CA  . ASP B 1 359 ? -22.818 -29.242 51.894  1.00 51.73  ? 359 ASP B CA  1 
ATOM 5271  C C   . ASP B 1 359 ? -22.709 -28.064 52.852  1.00 51.63  ? 359 ASP B C   1 
ATOM 5272  O O   . ASP B 1 359 ? -21.937 -27.137 52.585  1.00 46.91  ? 359 ASP B O   1 
ATOM 5273  C CB  . ASP B 1 359 ? -23.005 -28.723 50.468  1.00 58.66  ? 359 ASP B CB  1 
ATOM 5274  C CG  . ASP B 1 359 ? -24.262 -27.885 50.317  1.00 68.49  ? 359 ASP B CG  1 
ATOM 5275  O OD1 . ASP B 1 359 ? -25.231 -28.119 51.077  1.00 40.03  ? 359 ASP B OD1 1 
ATOM 5276  O OD2 . ASP B 1 359 ? -24.278 -26.986 49.447  1.00 68.03  ? 359 ASP B OD2 1 
ATOM 5277  N N   . GLN B 1 360 ? -23.463 -28.087 53.947  1.00 57.16  ? 360 GLN B N   1 
ATOM 5278  C CA  . GLN B 1 360 ? -23.442 -26.970 54.887  1.00 46.41  ? 360 GLN B CA  1 
ATOM 5279  C C   . GLN B 1 360 ? -22.074 -26.734 55.521  1.00 50.42  ? 360 GLN B C   1 
ATOM 5280  O O   . GLN B 1 360 ? -21.703 -25.558 55.679  1.00 49.62  ? 360 GLN B O   1 
ATOM 5281  C CB  . GLN B 1 360 ? -24.515 -27.189 55.963  1.00 55.03  ? 360 GLN B CB  1 
ATOM 5282  C CG  . GLN B 1 360 ? -25.922 -27.354 55.408  1.00 61.92  ? 360 GLN B CG  1 
ATOM 5283  C CD  . GLN B 1 360 ? -26.897 -27.883 56.439  1.00 66.43  ? 360 GLN B CD  1 
ATOM 5284  O OE1 . GLN B 1 360 ? -26.619 -27.867 57.640  1.00 71.48  ? 360 GLN B OE1 1 
ATOM 5285  N NE2 . GLN B 1 360 ? -28.045 -28.360 55.978  1.00 75.73  ? 360 GLN B NE2 1 
ATOM 5286  N N   . PRO B 1 361 ? -21.301 -27.752 55.922  1.00 56.90  ? 361 PRO B N   1 
ATOM 5287  C CA  . PRO B 1 361 ? -19.938 -27.453 56.401  1.00 54.18  ? 361 PRO B CA  1 
ATOM 5288  C C   . PRO B 1 361 ? -19.092 -26.734 55.363  1.00 57.21  ? 361 PRO B C   1 
ATOM 5289  O O   . PRO B 1 361 ? -18.496 -25.692 55.672  1.00 52.89  ? 361 PRO B O   1 
ATOM 5290  C CB  . PRO B 1 361 ? -19.384 -28.840 56.749  1.00 51.30  ? 361 PRO B CB  1 
ATOM 5291  C CG  . PRO B 1 361 ? -20.582 -29.641 57.085  1.00 50.18  ? 361 PRO B CG  1 
ATOM 5292  C CD  . PRO B 1 361 ? -21.643 -29.172 56.132  1.00 58.41  ? 361 PRO B CD  1 
ATOM 5293  N N   . LEU B 1 362 ? -19.046 -27.248 54.128  1.00 46.01  ? 362 LEU B N   1 
ATOM 5294  C CA  . LEU B 1 362 ? -18.271 -26.591 53.077  1.00 43.38  ? 362 LEU B CA  1 
ATOM 5295  C C   . LEU B 1 362 ? -18.691 -25.137 52.908  1.00 44.33  ? 362 LEU B C   1 
ATOM 5296  O O   . LEU B 1 362 ? -17.843 -24.261 52.704  1.00 46.82  ? 362 LEU B O   1 
ATOM 5297  C CB  . LEU B 1 362 ? -18.418 -27.341 51.751  1.00 45.22  ? 362 LEU B CB  1 
ATOM 5298  C CG  . LEU B 1 362 ? -17.872 -28.767 51.635  1.00 48.45  ? 362 LEU B CG  1 
ATOM 5299  C CD1 . LEU B 1 362 ? -16.520 -28.900 52.323  1.00 41.84  ? 362 LEU B CD1 1 
ATOM 5300  C CD2 . LEU B 1 362 ? -18.871 -29.792 52.168  1.00 65.12  ? 362 LEU B CD2 1 
ATOM 5301  N N   . ASN B 1 363 ? -19.994 -24.861 52.986  1.00 39.22  ? 363 ASN B N   1 
ATOM 5302  C CA  . ASN B 1 363 ? -20.451 -23.475 52.925  1.00 40.22  ? 363 ASN B CA  1 
ATOM 5303  C C   . ASN B 1 363 ? -19.873 -22.667 54.077  1.00 44.99  ? 363 ASN B C   1 
ATOM 5304  O O   . ASN B 1 363 ? -19.306 -21.588 53.873  1.00 45.50  ? 363 ASN B O   1 
ATOM 5305  C CB  . ASN B 1 363 ? -21.981 -23.418 52.943  1.00 45.03  ? 363 ASN B CB  1 
ATOM 5306  C CG  . ASN B 1 363 ? -22.611 -24.136 51.763  1.00 42.85  ? 363 ASN B CG  1 
ATOM 5307  O OD1 . ASN B 1 363 ? -21.960 -24.388 50.747  1.00 49.79  ? 363 ASN B OD1 1 
ATOM 5308  N ND2 . ASN B 1 363 ? -23.893 -24.462 51.889  1.00 35.77  ? 363 ASN B ND2 1 
ATOM 5309  N N   . GLY B 1 364 ? -19.984 -23.195 55.299  1.00 52.56  ? 364 GLY B N   1 
ATOM 5310  C CA  . GLY B 1 364 ? -19.543 -22.493 56.490  1.00 44.75  ? 364 GLY B CA  1 
ATOM 5311  C C   . GLY B 1 364 ? -18.114 -22.008 56.402  1.00 49.06  ? 364 GLY B C   1 
ATOM 5312  O O   . GLY B 1 364 ? -17.871 -20.797 56.381  1.00 55.71  ? 364 GLY B O   1 
ATOM 5313  N N   . LYS B 1 365 ? -17.163 -22.947 56.326  1.00 51.16  ? 365 LYS B N   1 
ATOM 5314  C CA  . LYS B 1 365 ? -15.763 -22.575 56.146  1.00 56.51  ? 365 LYS B CA  1 
ATOM 5315  C C   . LYS B 1 365 ? -15.576 -21.644 54.956  1.00 54.48  ? 365 LYS B C   1 
ATOM 5316  O O   . LYS B 1 365 ? -14.711 -20.759 55.001  1.00 53.15  ? 365 LYS B O   1 
ATOM 5317  C CB  . LYS B 1 365 ? -14.891 -23.822 55.987  1.00 52.43  ? 365 LYS B CB  1 
ATOM 5318  C CG  . LYS B 1 365 ? -15.251 -24.711 54.803  1.00 51.09  ? 365 LYS B CG  1 
ATOM 5319  C CD  . LYS B 1 365 ? -14.544 -26.060 54.900  1.00 58.34  ? 365 LYS B CD  1 
ATOM 5320  C CE  . LYS B 1 365 ? -13.035 -25.891 55.034  1.00 58.09  ? 365 LYS B CE  1 
ATOM 5321  N NZ  . LYS B 1 365 ? -12.336 -27.201 55.167  1.00 53.82  ? 365 LYS B NZ  1 
ATOM 5322  N N   . LEU B 1 366 ? -16.372 -21.813 53.896  1.00 49.57  ? 366 LEU B N   1 
ATOM 5323  C CA  . LEU B 1 366 ? -16.329 -20.872 52.781  1.00 47.43  ? 366 LEU B CA  1 
ATOM 5324  C C   . LEU B 1 366 ? -16.503 -19.440 53.281  1.00 52.72  ? 366 LEU B C   1 
ATOM 5325  O O   . LEU B 1 366 ? -15.625 -18.590 53.090  1.00 51.15  ? 366 LEU B O   1 
ATOM 5326  C CB  . LEU B 1 366 ? -17.402 -21.222 51.752  1.00 52.17  ? 366 LEU B CB  1 
ATOM 5327  C CG  . LEU B 1 366 ? -17.444 -20.333 50.506  1.00 43.45  ? 366 LEU B CG  1 
ATOM 5328  C CD1 . LEU B 1 366 ? -16.187 -20.488 49.661  1.00 38.71  ? 366 LEU B CD1 1 
ATOM 5329  C CD2 . LEU B 1 366 ? -18.686 -20.643 49.686  1.00 56.35  ? 366 LEU B CD2 1 
ATOM 5330  N N   . ALA B 1 367 ? -17.617 -19.165 53.962  1.00 46.46  ? 367 ALA B N   1 
ATOM 5331  C CA  . ALA B 1 367 ? -17.807 -17.843 54.553  1.00 49.22  ? 367 ALA B CA  1 
ATOM 5332  C C   . ALA B 1 367 ? -16.764 -17.531 55.616  1.00 47.21  ? 367 ALA B C   1 
ATOM 5333  O O   . ALA B 1 367 ? -16.481 -16.353 55.865  1.00 54.40  ? 367 ALA B O   1 
ATOM 5334  C CB  . ALA B 1 367 ? -19.218 -17.717 55.125  1.00 43.06  ? 367 ALA B CB  1 
ATOM 5335  N N   . ALA B 1 368 ? -16.163 -18.553 56.228  1.00 51.40  ? 368 ALA B N   1 
ATOM 5336  C CA  . ALA B 1 368 ? -15.047 -18.337 57.142  1.00 62.12  ? 368 ALA B CA  1 
ATOM 5337  C C   . ALA B 1 368 ? -13.737 -18.100 56.411  1.00 49.22  ? 368 ALA B C   1 
ATOM 5338  O O   . ALA B 1 368 ? -12.844 -17.444 56.958  1.00 47.39  ? 368 ALA B O   1 
ATOM 5339  C CB  . ALA B 1 368 ? -14.896 -19.523 58.092  1.00 62.70  ? 368 ALA B CB  1 
ATOM 5340  N N   . GLU B 1 369 ? -13.611 -18.602 55.184  1.00 50.58  ? 369 GLU B N   1 
ATOM 5341  C CA  . GLU B 1 369 ? -12.403 -18.367 54.400  1.00 51.17  ? 369 GLU B CA  1 
ATOM 5342  C C   . GLU B 1 369 ? -12.294 -16.907 53.979  1.00 50.44  ? 369 GLU B C   1 
ATOM 5343  O O   . GLU B 1 369 ? -11.200 -16.329 54.004  1.00 46.78  ? 369 GLU B O   1 
ATOM 5344  C CB  . GLU B 1 369 ? -12.390 -19.288 53.180  1.00 56.38  ? 369 GLU B CB  1 
ATOM 5345  C CG  . GLU B 1 369 ? -11.396 -18.915 52.095  1.00 55.64  ? 369 GLU B CG  1 
ATOM 5346  C CD  . GLU B 1 369 ? -11.461 -19.860 50.906  1.00 57.87  ? 369 GLU B CD  1 
ATOM 5347  O OE1 . GLU B 1 369 ? -11.496 -21.091 51.127  1.00 54.74  ? 369 GLU B OE1 1 
ATOM 5348  O OE2 . GLU B 1 369 ? -11.494 -19.376 49.754  1.00 66.90  ? 369 GLU B OE2 1 
ATOM 5349  N N   . VAL B 1 370 ? -13.416 -16.291 53.599  1.00 46.42  ? 370 VAL B N   1 
ATOM 5350  C CA  . VAL B 1 370 ? -13.402 -14.896 53.161  1.00 40.83  ? 370 VAL B CA  1 
ATOM 5351  C C   . VAL B 1 370 ? -13.433 -13.910 54.319  1.00 51.83  ? 370 VAL B C   1 
ATOM 5352  O O   . VAL B 1 370 ? -13.139 -12.726 54.117  1.00 55.65  ? 370 VAL B O   1 
ATOM 5353  C CB  . VAL B 1 370 ? -14.581 -14.606 52.214  1.00 50.34  ? 370 VAL B CB  1 
ATOM 5354  C CG1 . VAL B 1 370 ? -14.526 -15.529 51.004  1.00 53.81  ? 370 VAL B CG1 1 
ATOM 5355  C CG2 . VAL B 1 370 ? -15.904 -14.762 52.947  1.00 53.20  ? 370 VAL B CG2 1 
ATOM 5356  N N   . GLY B 1 371 ? -13.786 -14.362 55.520  1.00 60.99  ? 371 GLY B N   1 
ATOM 5357  C CA  . GLY B 1 371 ? -13.696 -13.538 56.708  1.00 54.86  ? 371 GLY B CA  1 
ATOM 5358  C C   . GLY B 1 371 ? -14.982 -12.895 57.182  1.00 55.46  ? 371 GLY B C   1 
ATOM 5359  O O   . GLY B 1 371 ? -14.919 -11.989 58.021  1.00 57.71  ? 371 GLY B O   1 
ATOM 5360  N N   . VAL B 1 372 ? -16.136 -13.326 56.687  1.00 49.61  ? 372 VAL B N   1 
ATOM 5361  C CA  . VAL B 1 372 ? -17.413 -12.743 57.085  1.00 55.02  ? 372 VAL B CA  1 
ATOM 5362  C C   . VAL B 1 372 ? -18.157 -13.645 58.074  1.00 49.46  ? 372 VAL B C   1 
ATOM 5363  O O   . VAL B 1 372 ? -19.357 -13.471 58.284  1.00 51.56  ? 372 VAL B O   1 
ATOM 5364  C CB  . VAL B 1 372 ? -18.289 -12.416 55.866  1.00 55.31  ? 372 VAL B CB  1 
ATOM 5365  C CG1 . VAL B 1 372 ? -17.585 -11.417 54.960  1.00 42.25  ? 372 VAL B CG1 1 
ATOM 5366  C CG2 . VAL B 1 372 ? -18.646 -13.684 55.108  1.00 45.50  ? 372 VAL B CG2 1 
ATOM 5367  N N   . GLY B 1 373 ? -17.466 -14.601 58.684  1.00 39.97  ? 373 GLY B N   1 
ATOM 5368  C CA  . GLY B 1 373 ? -18.110 -15.475 59.644  1.00 55.53  ? 373 GLY B CA  1 
ATOM 5369  C C   . GLY B 1 373 ? -17.081 -16.296 60.390  1.00 61.66  ? 373 GLY B C   1 
ATOM 5370  O O   . GLY B 1 373 ? -15.879 -16.225 60.123  1.00 71.66  ? 373 GLY B O   1 
ATOM 5371  N N   . MET B 1 374 ? -17.579 -17.085 61.341  1.00 61.31  ? 374 MET B N   1 
ATOM 5372  C CA  . MET B 1 374 ? -16.727 -17.962 62.132  1.00 62.66  ? 374 MET B CA  1 
ATOM 5373  C C   . MET B 1 374 ? -17.508 -19.201 62.538  1.00 63.76  ? 374 MET B C   1 
ATOM 5374  O O   . MET B 1 374 ? -18.685 -19.113 62.894  1.00 72.42  ? 374 MET B O   1 
ATOM 5375  C CB  . MET B 1 374 ? -16.194 -17.259 63.383  1.00 62.33  ? 374 MET B CB  1 
ATOM 5376  C CG  . MET B 1 374 ? -15.079 -18.027 64.075  1.00 79.76  ? 374 MET B CG  1 
ATOM 5377  S SD  . MET B 1 374 ? -15.111 -17.886 65.872  1.00 106.58 ? 374 MET B SD  1 
ATOM 5378  C CE  . MET B 1 374 ? -15.036 -16.110 66.077  1.00 83.07  ? 374 MET B CE  1 
ATOM 5379  N N   . GLU B 1 375 ? -16.846 -20.353 62.484  1.00 61.59  ? 375 GLU B N   1 
ATOM 5380  C CA  . GLU B 1 375 ? -17.462 -21.619 62.849  1.00 59.80  ? 375 GLU B CA  1 
ATOM 5381  C C   . GLU B 1 375 ? -17.237 -21.919 64.325  1.00 75.25  ? 375 GLU B C   1 
ATOM 5382  O O   . GLU B 1 375 ? -16.220 -21.531 64.911  1.00 80.67  ? 375 GLU B O   1 
ATOM 5383  C CB  . GLU B 1 375 ? -16.896 -22.764 62.007  1.00 52.92  ? 375 GLU B CB  1 
ATOM 5384  C CG  . GLU B 1 375 ? -16.436 -22.358 60.625  1.00 57.75  ? 375 GLU B CG  1 
ATOM 5385  C CD  . GLU B 1 375 ? -15.933 -23.537 59.817  1.00 61.11  ? 375 GLU B CD  1 
ATOM 5386  O OE1 . GLU B 1 375 ? -16.660 -24.550 59.727  1.00 59.15  ? 375 GLU B OE1 1 
ATOM 5387  O OE2 . GLU B 1 375 ? -14.807 -23.456 59.284  1.00 60.89  ? 375 GLU B OE2 1 
ATOM 5388  N N   . VAL B 1 376 ? -18.199 -22.619 64.927  1.00 70.66  ? 376 VAL B N   1 
ATOM 5389  C CA  . VAL B 1 376 ? -18.022 -23.080 66.296  1.00 74.90  ? 376 VAL B CA  1 
ATOM 5390  C C   . VAL B 1 376 ? -17.054 -24.258 66.302  1.00 84.08  ? 376 VAL B C   1 
ATOM 5391  O O   . VAL B 1 376 ? -17.010 -25.064 65.361  1.00 78.68  ? 376 VAL B O   1 
ATOM 5392  C CB  . VAL B 1 376 ? -19.370 -23.453 66.937  1.00 76.60  ? 376 VAL B CB  1 
ATOM 5393  C CG1 . VAL B 1 376 ? -20.360 -22.314 66.784  1.00 71.96  ? 376 VAL B CG1 1 
ATOM 5394  C CG2 . VAL B 1 376 ? -19.928 -24.732 66.335  1.00 82.11  ? 376 VAL B CG2 1 
ATOM 5395  N N   . VAL B 1 377 ? -16.257 -24.353 67.361  1.00 91.89  ? 377 VAL B N   1 
ATOM 5396  C CA  . VAL B 1 377 ? -15.248 -25.398 67.479  1.00 93.74  ? 377 VAL B CA  1 
ATOM 5397  C C   . VAL B 1 377 ? -15.893 -26.621 68.114  1.00 99.59  ? 377 VAL B C   1 
ATOM 5398  O O   . VAL B 1 377 ? -16.369 -26.562 69.253  1.00 108.46 ? 377 VAL B O   1 
ATOM 5399  C CB  . VAL B 1 377 ? -14.042 -24.916 68.297  1.00 106.26 ? 377 VAL B CB  1 
ATOM 5400  C CG1 . VAL B 1 377 ? -12.898 -25.916 68.193  1.00 102.52 ? 377 VAL B CG1 1 
ATOM 5401  C CG2 . VAL B 1 377 ? -13.599 -23.538 67.831  1.00 100.04 ? 377 VAL B CG2 1 
ATOM 5402  N N   . ARG B 1 378 ? -15.944 -27.724 67.358  1.00 99.79  ? 378 ARG B N   1 
ATOM 5403  C CA  . ARG B 1 378 ? -16.598 -28.965 67.855  1.00 103.71 ? 378 ARG B CA  1 
ATOM 5404  C C   . ARG B 1 378 ? -15.732 -29.608 68.941  1.00 110.17 ? 378 ARG B C   1 
ATOM 5405  O O   . ARG B 1 378 ? -14.546 -29.877 68.665  1.00 114.44 ? 378 ARG B O   1 
ATOM 5406  C CB  . ARG B 1 378 ? -16.829 -29.941 66.697  1.00 111.19 ? 378 ARG B CB  1 
ATOM 5407  C CG  . ARG B 1 378 ? -17.831 -31.044 67.001  1.00 117.12 ? 378 ARG B CG  1 
ATOM 5408  C CD  . ARG B 1 378 ? -18.391 -31.678 65.742  1.00 122.39 ? 378 ARG B CD  1 
ATOM 5409  N NE  . ARG B 1 378 ? -19.846 -31.644 65.703  1.00 118.27 ? 378 ARG B NE  1 
ATOM 5410  C CZ  . ARG B 1 378 ? -20.562 -31.469 64.597  1.00 109.70 ? 378 ARG B CZ  1 
ATOM 5411  N NH1 . ARG B 1 378 ? -19.956 -31.311 63.434  1.00 100.87 ? 378 ARG B NH1 1 
ATOM 5412  N NH2 . ARG B 1 378 ? -21.881 -31.447 64.661  1.00 106.38 ? 378 ARG B NH2 1 
ATOM 5413  N N   . ASP B 1 379 ? -16.308 -29.847 70.122  1.00 109.20 ? 379 ASP B N   1 
ATOM 5414  C CA  . ASP B 1 379 ? -15.557 -30.513 71.222  1.00 119.71 ? 379 ASP B CA  1 
ATOM 5415  C C   . ASP B 1 379 ? -15.748 -32.030 71.106  1.00 118.92 ? 379 ASP B C   1 
ATOM 5416  O O   . ASP B 1 379 ? -14.836 -32.770 71.523  1.00 116.81 ? 379 ASP B O   1 
ATOM 5417  C CB  . ASP B 1 379 ? -15.993 -29.985 72.591  1.00 126.47 ? 379 ASP B CB  1 
ATOM 5418  C CG  . ASP B 1 379 ? -15.533 -28.563 72.858  1.00 130.09 ? 379 ASP B CG  1 
ATOM 5419  O OD1 . ASP B 1 379 ? -14.646 -28.087 72.121  1.00 119.70 ? 379 ASP B OD1 1 
ATOM 5420  O OD2 . ASP B 1 379 ? -16.068 -27.945 73.799  1.00 136.31 ? 379 ASP B OD2 1 
ATOM 5421  N N   . GLU B 1 380 ? -16.887 -32.465 70.557  1.00 119.07 ? 380 GLU B N   1 
ATOM 5422  C CA  . GLU B 1 380 ? -17.153 -33.917 70.381  1.00 126.98 ? 380 GLU B CA  1 
ATOM 5423  C C   . GLU B 1 380 ? -17.087 -34.260 68.889  1.00 128.59 ? 380 GLU B C   1 
ATOM 5424  O O   . GLU B 1 380 ? -16.137 -33.804 68.224  1.00 123.27 ? 380 GLU B O   1 
ATOM 5425  C CB  . GLU B 1 380 ? -18.517 -34.279 70.972  1.00 125.90 ? 380 GLU B CB  1 
ATOM 5426  C CG  . GLU B 1 380 ? -18.580 -34.142 72.483  1.00 130.76 ? 380 GLU B CG  1 
ATOM 5427  C CD  . GLU B 1 380 ? -19.950 -34.429 73.074  1.00 139.21 ? 380 GLU B CD  1 
ATOM 5428  O OE1 . GLU B 1 380 ? -20.913 -34.554 72.293  1.00 142.82 ? 380 GLU B OE1 1 
ATOM 5429  O OE2 . GLU B 1 380 ? -20.047 -34.538 74.312  1.00 142.15 ? 380 GLU B OE2 1 
ATOM 5430  N N   . ASN B 1 381 ? -18.053 -35.038 68.393  1.00 135.43 ? 381 ASN B N   1 
ATOM 5431  C CA  . ASN B 1 381 ? -18.104 -35.396 66.950  1.00 143.85 ? 381 ASN B CA  1 
ATOM 5432  C C   . ASN B 1 381 ? -19.555 -35.275 66.482  1.00 140.30 ? 381 ASN B C   1 
ATOM 5433  O O   . ASN B 1 381 ? -19.771 -34.989 65.289  1.00 132.68 ? 381 ASN B O   1 
ATOM 5434  C CB  . ASN B 1 381 ? -17.521 -36.786 66.675  1.00 146.01 ? 381 ASN B CB  1 
ATOM 5435  C CG  . ASN B 1 381 ? -17.843 -37.801 67.752  1.00 144.69 ? 381 ASN B CG  1 
ATOM 5436  O OD1 . ASN B 1 381 ? -18.966 -38.293 67.835  1.00 143.12 ? 381 ASN B OD1 1 
ATOM 5437  N ND2 . ASN B 1 381 ? -16.860 -38.133 68.574  1.00 145.13 ? 381 ASN B ND2 1 
ATOM 5438  N N   . GLY B 1 382 ? -20.499 -35.482 67.395  1.00 135.64 ? 382 GLY B N   1 
ATOM 5439  C CA  . GLY B 1 382 ? -21.928 -35.356 67.049  1.00 127.59 ? 382 GLY B CA  1 
ATOM 5440  C C   . GLY B 1 382 ? -22.391 -33.915 67.153  1.00 125.18 ? 382 GLY B C   1 
ATOM 5441  O O   . GLY B 1 382 ? -23.175 -33.485 66.283  1.00 111.80 ? 382 GLY B O   1 
ATOM 5442  N N   . LYS B 1 383 ? -21.931 -33.209 68.183  1.00 127.11 ? 383 LYS B N   1 
ATOM 5443  C CA  . LYS B 1 383 ? -22.476 -31.846 68.364  1.00 118.93 ? 383 LYS B CA  1 
ATOM 5444  C C   . LYS B 1 383 ? -21.478 -30.933 69.062  1.00 107.67 ? 383 LYS B C   1 
ATOM 5445  O O   . LYS B 1 383 ? -20.332 -31.347 69.298  1.00 108.95 ? 383 LYS B O   1 
ATOM 5446  C CB  . LYS B 1 383 ? -23.794 -31.892 69.141  1.00 114.62 ? 383 LYS B CB  1 
ATOM 5447  C CG  . LYS B 1 383 ? -23.741 -32.582 70.499  1.00 113.45 ? 383 LYS B CG  1 
ATOM 5448  C CD  . LYS B 1 383 ? -24.922 -32.237 71.380  1.00 114.04 ? 383 LYS B CD  1 
ATOM 5449  C CE  . LYS B 1 383 ? -25.452 -33.418 72.168  1.00 116.64 ? 383 LYS B CE  1 
ATOM 5450  N NZ  . LYS B 1 383 ? -26.052 -34.453 71.293  1.00 123.35 ? 383 LYS B NZ  1 
ATOM 5451  N N   . TYR B 1 384 ? -21.944 -29.735 69.387  1.00 101.62 ? 384 TYR B N   1 
ATOM 5452  C CA  . TYR B 1 384 ? -21.066 -28.740 70.027  1.00 106.31 ? 384 TYR B CA  1 
ATOM 5453  C C   . TYR B 1 384 ? -21.561 -28.499 71.448  1.00 105.72 ? 384 TYR B C   1 
ATOM 5454  O O   . TYR B 1 384 ? -22.640 -29.007 71.806  1.00 104.21 ? 384 TYR B O   1 
ATOM 5455  C CB  . TYR B 1 384 ? -21.161 -27.449 69.224  1.00 105.96 ? 384 TYR B CB  1 
ATOM 5456  C CG  . TYR B 1 384 ? -21.187 -27.644 67.733  1.00 98.81  ? 384 TYR B CG  1 
ATOM 5457  C CD1 . TYR B 1 384 ? -20.054 -28.061 67.064  1.00 99.19  ? 384 TYR B CD1 1 
ATOM 5458  C CD2 . TYR B 1 384 ? -22.328 -27.395 66.989  1.00 92.49  ? 384 TYR B CD2 1 
ATOM 5459  C CE1 . TYR B 1 384 ? -20.046 -28.220 65.692  1.00 104.78 ? 384 TYR B CE1 1 
ATOM 5460  C CE2 . TYR B 1 384 ? -22.342 -27.557 65.614  1.00 83.80  ? 384 TYR B CE2 1 
ATOM 5461  C CZ  . TYR B 1 384 ? -21.193 -27.970 64.967  1.00 92.27  ? 384 TYR B CZ  1 
ATOM 5462  O OH  . TYR B 1 384 ? -21.160 -28.136 63.619  1.00 87.87  ? 384 TYR B OH  1 
ATOM 5463  N N   . LYS B 1 385 ? -20.798 -27.723 72.218  1.00 102.49 ? 385 LYS B N   1 
ATOM 5464  C CA  . LYS B 1 385 ? -21.149 -27.488 73.637  1.00 104.11 ? 385 LYS B CA  1 
ATOM 5465  C C   . LYS B 1 385 ? -21.434 -26.001 73.838  1.00 103.42 ? 385 LYS B C   1 
ATOM 5466  O O   . LYS B 1 385 ? -20.995 -25.214 72.993  1.00 103.14 ? 385 LYS B O   1 
ATOM 5467  C CB  . LYS B 1 385 ? -20.006 -28.002 74.512  1.00 116.27 ? 385 LYS B CB  1 
ATOM 5468  C CG  . LYS B 1 385 ? -19.689 -29.482 74.356  1.00 118.67 ? 385 LYS B CG  1 
ATOM 5469  C CD  . LYS B 1 385 ? -18.767 -30.000 75.435  1.00 126.21 ? 385 LYS B CD  1 
ATOM 5470  C CE  . LYS B 1 385 ? -18.365 -31.444 75.231  1.00 128.52 ? 385 LYS B CE  1 
ATOM 5471  N NZ  . LYS B 1 385 ? -17.027 -31.722 75.803  1.00 132.56 ? 385 LYS B NZ  1 
ATOM 5472  N N   . ARG B 1 386 ? -22.129 -25.641 74.917  1.00 105.37 ? 386 ARG B N   1 
ATOM 5473  C CA  . ARG B 1 386 ? -22.544 -24.234 75.125  1.00 102.80 ? 386 ARG B CA  1 
ATOM 5474  C C   . ARG B 1 386 ? -21.347 -23.292 75.103  1.00 94.08  ? 386 ARG B C   1 
ATOM 5475  O O   . ARG B 1 386 ? -21.471 -22.222 74.504  1.00 93.17  ? 386 ARG B O   1 
ATOM 5476  C CB  . ARG B 1 386 ? -23.214 -24.137 76.495  1.00 105.44 ? 386 ARG B CB  1 
ATOM 5477  C CG  . ARG B 1 386 ? -24.264 -25.210 76.736  1.00 98.05  ? 386 ARG B CG  1 
ATOM 5478  C CD  . ARG B 1 386 ? -24.163 -25.930 78.066  1.00 91.55  ? 386 ARG B CD  1 
ATOM 5479  N NE  . ARG B 1 386 ? -25.398 -26.658 78.313  1.00 99.60  ? 386 ARG B NE  1 
ATOM 5480  C CZ  . ARG B 1 386 ? -25.483 -27.813 78.963  1.00 104.76 ? 386 ARG B CZ  1 
ATOM 5481  N NH1 . ARG B 1 386 ? -24.394 -28.384 79.446  1.00 109.33 ? 386 ARG B NH1 1 
ATOM 5482  N NH2 . ARG B 1 386 ? -26.660 -28.390 79.127  1.00 110.49 ? 386 ARG B NH2 1 
ATOM 5483  N N   . GLU B 1 387 ? -20.265 -23.643 75.776  1.00 94.21  ? 387 GLU B N   1 
ATOM 5484  C CA  . GLU B 1 387 ? -19.047 -22.792 75.701  1.00 104.07 ? 387 GLU B CA  1 
ATOM 5485  C C   . GLU B 1 387 ? -18.698 -22.505 74.238  1.00 102.42 ? 387 GLU B C   1 
ATOM 5486  O O   . GLU B 1 387 ? -18.616 -21.318 73.893  1.00 99.58  ? 387 GLU B O   1 
ATOM 5487  C CB  . GLU B 1 387 ? -17.874 -23.461 76.418  1.00 95.56  ? 387 GLU B CB  1 
ATOM 5488  C CG  . GLU B 1 387 ? -17.665 -22.950 77.832  1.00 98.63  ? 387 GLU B CG  1 
ATOM 5489  C CD  . GLU B 1 387 ? -17.664 -21.438 77.975  1.00 109.94 ? 387 GLU B CD  1 
ATOM 5490  O OE1 . GLU B 1 387 ? -16.737 -20.795 77.445  1.00 117.83 ? 387 GLU B OE1 1 
ATOM 5491  O OE2 . GLU B 1 387 ? -18.584 -20.905 78.628  1.00 108.17 ? 387 GLU B OE2 1 
ATOM 5492  N N   . GLY B 1 388 ? -18.484 -23.545 73.423  1.00 96.97  ? 388 GLY B N   1 
ATOM 5493  C CA  . GLY B 1 388 ? -18.129 -23.352 72.027  1.00 92.60  ? 388 GLY B CA  1 
ATOM 5494  C C   . GLY B 1 388 ? -19.041 -22.380 71.305  1.00 97.06  ? 388 GLY B C   1 
ATOM 5495  O O   . GLY B 1 388 ? -18.602 -21.663 70.401  1.00 96.27  ? 388 GLY B O   1 
ATOM 5496  N N   . ILE B 1 389 ? -20.316 -22.331 71.693  1.00 95.29  ? 389 ILE B N   1 
ATOM 5497  C CA  . ILE B 1 389 ? -21.266 -21.433 71.047  1.00 89.11  ? 389 ILE B CA  1 
ATOM 5498  C C   . ILE B 1 389 ? -21.158 -20.026 71.624  1.00 88.90  ? 389 ILE B C   1 
ATOM 5499  O O   . ILE B 1 389 ? -21.079 -19.037 70.882  1.00 92.92  ? 389 ILE B O   1 
ATOM 5500  C CB  . ILE B 1 389 ? -22.694 -21.990 71.186  1.00 83.69  ? 389 ILE B CB  1 
ATOM 5501  C CG1 . ILE B 1 389 ? -22.811 -23.338 70.474  1.00 83.41  ? 389 ILE B CG1 1 
ATOM 5502  C CG2 . ILE B 1 389 ? -23.713 -20.995 70.651  1.00 83.28  ? 389 ILE B CG2 1 
ATOM 5503  C CD1 . ILE B 1 389 ? -24.196 -23.938 70.526  1.00 88.32  ? 389 ILE B CD1 1 
ATOM 5504  N N   . ALA B 1 390 ? -21.168 -19.924 72.953  1.00 91.84  ? 390 ALA B N   1 
ATOM 5505  C CA  . ALA B 1 390 ? -21.111 -18.619 73.602  1.00 93.73  ? 390 ALA B CA  1 
ATOM 5506  C C   . ALA B 1 390 ? -19.816 -17.891 73.267  1.00 93.29  ? 390 ALA B C   1 
ATOM 5507  O O   . ALA B 1 390 ? -19.821 -16.674 73.045  1.00 89.35  ? 390 ALA B O   1 
ATOM 5508  C CB  . ALA B 1 390 ? -21.260 -18.779 75.114  1.00 92.84  ? 390 ALA B CB  1 
ATOM 5509  N N   . GLU B 1 391 ? -18.696 -18.616 73.231  1.00 94.96  ? 391 GLU B N   1 
ATOM 5510  C CA  . GLU B 1 391 ? -17.419 -17.992 72.908  1.00 94.75  ? 391 GLU B CA  1 
ATOM 5511  C C   . GLU B 1 391 ? -17.471 -17.320 71.543  1.00 91.36  ? 391 GLU B C   1 
ATOM 5512  O O   . GLU B 1 391 ? -17.129 -16.141 71.412  1.00 85.09  ? 391 GLU B O   1 
ATOM 5513  C CB  . GLU B 1 391 ? -16.294 -19.028 72.955  1.00 94.18  ? 391 GLU B CB  1 
ATOM 5514  C CG  . GLU B 1 391 ? -15.771 -19.317 74.354  1.00 106.41 ? 391 GLU B CG  1 
ATOM 5515  C CD  . GLU B 1 391 ? -14.605 -20.288 74.348  1.00 113.51 ? 391 GLU B CD  1 
ATOM 5516  O OE1 . GLU B 1 391 ? -14.050 -20.542 73.259  1.00 110.48 ? 391 GLU B OE1 1 
ATOM 5517  O OE2 . GLU B 1 391 ? -14.248 -20.796 75.431  1.00 112.58 ? 391 GLU B OE2 1 
ATOM 5518  N N   . VAL B 1 392 ? -17.915 -18.051 70.518  1.00 91.54  ? 392 VAL B N   1 
ATOM 5519  C CA  . VAL B 1 392 ? -17.906 -17.485 69.174  1.00 86.17  ? 392 VAL B CA  1 
ATOM 5520  C C   . VAL B 1 392 ? -18.941 -16.374 69.045  1.00 83.92  ? 392 VAL B C   1 
ATOM 5521  O O   . VAL B 1 392 ? -18.699 -15.380 68.348  1.00 84.85  ? 392 VAL B O   1 
ATOM 5522  C CB  . VAL B 1 392 ? -18.103 -18.586 68.115  1.00 78.84  ? 392 VAL B CB  1 
ATOM 5523  C CG1 . VAL B 1 392 ? -17.053 -19.678 68.290  1.00 89.48  ? 392 VAL B CG1 1 
ATOM 5524  C CG2 . VAL B 1 392 ? -19.494 -19.177 68.197  1.00 88.73  ? 392 VAL B CG2 1 
ATOM 5525  N N   . ILE B 1 393 ? -20.086 -16.496 69.726  1.00 83.83  ? 393 ILE B N   1 
ATOM 5526  C CA  . ILE B 1 393 ? -21.079 -15.421 69.675  1.00 82.88  ? 393 ILE B CA  1 
ATOM 5527  C C   . ILE B 1 393 ? -20.494 -14.138 70.253  1.00 88.23  ? 393 ILE B C   1 
ATOM 5528  O O   . ILE B 1 393 ? -20.575 -13.064 69.640  1.00 80.14  ? 393 ILE B O   1 
ATOM 5529  C CB  . ILE B 1 393 ? -22.369 -15.834 70.405  1.00 75.80  ? 393 ILE B CB  1 
ATOM 5530  C CG1 . ILE B 1 393 ? -23.091 -16.928 69.623  1.00 72.81  ? 393 ILE B CG1 1 
ATOM 5531  C CG2 . ILE B 1 393 ? -23.280 -14.628 70.594  1.00 79.08  ? 393 ILE B CG2 1 
ATOM 5532  C CD1 . ILE B 1 393 ? -24.361 -17.407 70.285  1.00 84.91  ? 393 ILE B CD1 1 
ATOM 5533  N N   . ARG B 1 394 ? -19.877 -14.232 71.434  1.00 89.57  ? 394 ARG B N   1 
ATOM 5534  C CA  . ARG B 1 394 ? -19.280 -13.050 72.051  1.00 85.70  ? 394 ARG B CA  1 
ATOM 5535  C C   . ARG B 1 394 ? -18.147 -12.498 71.197  1.00 87.13  ? 394 ARG B C   1 
ATOM 5536  O O   . ARG B 1 394 ? -18.028 -11.278 71.032  1.00 87.06  ? 394 ARG B O   1 
ATOM 5537  C CB  . ARG B 1 394 ? -18.777 -13.381 73.457  1.00 95.42  ? 394 ARG B CB  1 
ATOM 5538  C CG  . ARG B 1 394 ? -19.850 -13.879 74.409  1.00 99.76  ? 394 ARG B CG  1 
ATOM 5539  C CD  . ARG B 1 394 ? -19.267 -14.205 75.777  1.00 104.77 ? 394 ARG B CD  1 
ATOM 5540  N NE  . ARG B 1 394 ? -19.190 -13.032 76.638  1.00 113.45 ? 394 ARG B NE  1 
ATOM 5541  C CZ  . ARG B 1 394 ? -20.105 -12.708 77.544  1.00 110.95 ? 394 ARG B CZ  1 
ATOM 5542  N NH1 . ARG B 1 394 ? -21.177 -13.456 77.739  1.00 107.62 ? 394 ARG B NH1 1 
ATOM 5543  N NH2 . ARG B 1 394 ? -19.935 -11.608 78.272  1.00 103.92 ? 394 ARG B NH2 1 
ATOM 5544  N N   . LYS B 1 395 ? -17.311 -13.379 70.641  1.00 91.38  ? 395 LYS B N   1 
ATOM 5545  C CA  . LYS B 1 395 ? -16.191 -12.929 69.819  1.00 89.52  ? 395 LYS B CA  1 
ATOM 5546  C C   . LYS B 1 395 ? -16.681 -12.150 68.607  1.00 82.97  ? 395 LYS B C   1 
ATOM 5547  O O   . LYS B 1 395 ? -16.160 -11.072 68.298  1.00 89.03  ? 395 LYS B O   1 
ATOM 5548  C CB  . LYS B 1 395 ? -15.347 -14.129 69.381  1.00 83.39  ? 395 LYS B CB  1 
ATOM 5549  C CG  . LYS B 1 395 ? -14.545 -14.780 70.500  1.00 89.94  ? 395 LYS B CG  1 
ATOM 5550  C CD  . LYS B 1 395 ? -14.149 -16.207 70.138  1.00 95.86  ? 395 LYS B CD  1 
ATOM 5551  C CE  . LYS B 1 395 ? -12.872 -16.251 69.317  1.00 98.67  ? 395 LYS B CE  1 
ATOM 5552  N NZ  . LYS B 1 395 ? -11.677 -15.918 70.145  1.00 90.80  ? 395 LYS B NZ  1 
ATOM 5553  N N   . VAL B 1 396 ? -17.696 -12.668 67.918  1.00 77.33  ? 396 VAL B N   1 
ATOM 5554  C CA  . VAL B 1 396 ? -18.144 -12.049 66.676  1.00 83.58  ? 396 VAL B CA  1 
ATOM 5555  C C   . VAL B 1 396 ? -18.935 -10.777 66.957  1.00 79.60  ? 396 VAL B C   1 
ATOM 5556  O O   . VAL B 1 396 ? -18.593 -9.693  66.468  1.00 86.70  ? 396 VAL B O   1 
ATOM 5557  C CB  . VAL B 1 396 ? -18.969 -13.047 65.840  1.00 76.16  ? 396 VAL B CB  1 
ATOM 5558  C CG1 . VAL B 1 396 ? -19.639 -12.335 64.674  1.00 61.13  ? 396 VAL B CG1 1 
ATOM 5559  C CG2 . VAL B 1 396 ? -18.079 -14.171 65.342  1.00 73.39  ? 396 VAL B CG2 1 
ATOM 5560  N N   . VAL B 1 397 ? -20.000 -10.880 67.751  1.00 76.91  ? 397 VAL B N   1 
ATOM 5561  C CA  . VAL B 1 397 ? -20.989 -9.803  67.766  1.00 80.16  ? 397 VAL B CA  1 
ATOM 5562  C C   . VAL B 1 397 ? -20.581 -8.665  68.697  1.00 85.82  ? 397 VAL B C   1 
ATOM 5563  O O   . VAL B 1 397 ? -20.809 -7.492  68.388  1.00 88.09  ? 397 VAL B O   1 
ATOM 5564  C CB  . VAL B 1 397 ? -22.377 -10.360 68.128  1.00 89.38  ? 397 VAL B CB  1 
ATOM 5565  C CG1 . VAL B 1 397 ? -23.439 -9.276  67.971  1.00 83.88  ? 397 VAL B CG1 1 
ATOM 5566  C CG2 . VAL B 1 397 ? -22.710 -11.562 67.250  1.00 86.75  ? 397 VAL B CG2 1 
ATOM 5567  N N   . VAL B 1 398 ? -19.972 -8.973  69.842  1.00 88.89  ? 398 VAL B N   1 
ATOM 5568  C CA  . VAL B 1 398 ? -19.800 -7.986  70.906  1.00 83.46  ? 398 VAL B CA  1 
ATOM 5569  C C   . VAL B 1 398 ? -18.343 -7.731  71.275  1.00 84.32  ? 398 VAL B C   1 
ATOM 5570  O O   . VAL B 1 398 ? -18.072 -6.767  72.007  1.00 89.27  ? 398 VAL B O   1 
ATOM 5571  C CB  . VAL B 1 398 ? -20.600 -8.390  72.165  1.00 90.08  ? 398 VAL B CB  1 
ATOM 5572  C CG1 . VAL B 1 398 ? -19.817 -9.381  73.011  1.00 95.09  ? 398 VAL B CG1 1 
ATOM 5573  C CG2 . VAL B 1 398 ? -21.002 -7.166  72.974  1.00 87.91  ? 398 VAL B CG2 1 
ATOM 5574  N N   . GLU B 1 399 ? -17.397 -8.538  70.806  1.00 86.75  ? 399 GLU B N   1 
ATOM 5575  C CA  . GLU B 1 399 ? -16.004 -8.390  71.203  1.00 89.51  ? 399 GLU B CA  1 
ATOM 5576  C C   . GLU B 1 399 ? -15.194 -7.715  70.103  1.00 91.37  ? 399 GLU B C   1 
ATOM 5577  O O   . GLU B 1 399 ? -15.577 -7.702  68.932  1.00 92.75  ? 399 GLU B O   1 
ATOM 5578  C CB  . GLU B 1 399 ? -15.391 -9.752  71.549  1.00 92.08  ? 399 GLU B CB  1 
ATOM 5579  C CG  . GLU B 1 399 ? -14.533 -9.754  72.813  1.00 102.14 ? 399 GLU B CG  1 
ATOM 5580  C CD  . GLU B 1 399 ? -13.144 -9.189  72.586  1.00 112.35 ? 399 GLU B CD  1 
ATOM 5581  O OE1 . GLU B 1 399 ? -12.678 -9.211  71.428  1.00 109.18 ? 399 GLU B OE1 1 
ATOM 5582  O OE2 . GLU B 1 399 ? -12.519 -8.722  73.564  1.00 118.93 ? 399 GLU B OE2 1 
ATOM 5583  N N   . LYS B 1 400 ? -14.051 -7.151  70.503  1.00 96.97  ? 400 LYS B N   1 
ATOM 5584  C CA  . LYS B 1 400 ? -13.174 -6.489  69.543  1.00 94.72  ? 400 LYS B CA  1 
ATOM 5585  C C   . LYS B 1 400 ? -12.502 -7.483  68.604  1.00 85.97  ? 400 LYS B C   1 
ATOM 5586  O O   . LYS B 1 400 ? -12.216 -7.143  67.452  1.00 90.44  ? 400 LYS B O   1 
ATOM 5587  C CB  . LYS B 1 400 ? -12.108 -5.669  70.271  1.00 93.12  ? 400 LYS B CB  1 
ATOM 5588  C CG  . LYS B 1 400 ? -12.649 -4.502  71.073  1.00 98.69  ? 400 LYS B CG  1 
ATOM 5589  C CD  . LYS B 1 400 ? -11.519 -3.706  71.717  1.00 109.90 ? 400 LYS B CD  1 
ATOM 5590  C CE  . LYS B 1 400 ? -12.045 -2.487  72.457  1.00 101.03 ? 400 LYS B CE  1 
ATOM 5591  N NZ  . LYS B 1 400 ? -10.945 -1.718  73.105  1.00 102.83 ? 400 LYS B NZ  1 
ATOM 5592  N N   . SER B 1 401 ? -12.234 -8.705  69.077  1.00 85.65  ? 401 SER B N   1 
ATOM 5593  C CA  . SER B 1 401 ? -11.558 -9.698  68.247  1.00 91.03  ? 401 SER B CA  1 
ATOM 5594  C C   . SER B 1 401 ? -12.347 -10.037 66.990  1.00 92.40  ? 401 SER B C   1 
ATOM 5595  O O   . SER B 1 401 ? -11.755 -10.479 65.997  1.00 93.81  ? 401 SER B O   1 
ATOM 5596  C CB  . SER B 1 401 ? -11.298 -10.971 69.055  1.00 96.92  ? 401 SER B CB  1 
ATOM 5597  O OG  . SER B 1 401 ? -12.515 -11.575 69.456  1.00 99.42  ? 401 SER B OG  1 
ATOM 5598  N N   . GLY B 1 402 ? -13.661 -9.837  67.004  1.00 91.90  ? 402 GLY B N   1 
ATOM 5599  C CA  . GLY B 1 402 ? -14.497 -10.058 65.847  1.00 89.65  ? 402 GLY B CA  1 
ATOM 5600  C C   . GLY B 1 402 ? -14.694 -8.848  64.963  1.00 83.25  ? 402 GLY B C   1 
ATOM 5601  O O   . GLY B 1 402 ? -15.467 -8.924  64.001  1.00 85.27  ? 402 GLY B O   1 
ATOM 5602  N N   . GLU B 1 403 ? -14.018 -7.729  65.257  1.00 75.86  ? 403 GLU B N   1 
ATOM 5603  C CA  . GLU B 1 403 ? -14.146 -6.547  64.409  1.00 75.95  ? 403 GLU B CA  1 
ATOM 5604  C C   . GLU B 1 403 ? -13.723 -6.854  62.977  1.00 82.26  ? 403 GLU B C   1 
ATOM 5605  O O   . GLU B 1 403 ? -14.381 -6.424  62.021  1.00 83.52  ? 403 GLU B O   1 
ATOM 5606  C CB  . GLU B 1 403 ? -13.326 -5.397  64.989  1.00 80.06  ? 403 GLU B CB  1 
ATOM 5607  C CG  . GLU B 1 403 ? -13.899 -4.020  64.685  1.00 95.36  ? 403 GLU B CG  1 
ATOM 5608  C CD  . GLU B 1 403 ? -13.102 -3.267  63.638  1.00 97.99  ? 403 GLU B CD  1 
ATOM 5609  O OE1 . GLU B 1 403 ? -11.878 -3.504  63.536  1.00 94.13  ? 403 GLU B OE1 1 
ATOM 5610  O OE2 . GLU B 1 403 ? -13.697 -2.438  62.916  1.00 96.15  ? 403 GLU B OE2 1 
ATOM 5611  N N   . VAL B 1 404 ? -12.664 -7.634  62.824  1.00 81.83  ? 404 VAL B N   1 
ATOM 5612  C CA  . VAL B 1 404 ? -12.281 -8.028  61.443  1.00 71.98  ? 404 VAL B CA  1 
ATOM 5613  C C   . VAL B 1 404 ? -13.533 -8.578  60.756  1.00 73.77  ? 404 VAL B C   1 
ATOM 5614  O O   . VAL B 1 404 ? -13.923 -8.014  59.706  1.00 76.05  ? 404 VAL B O   1 
ATOM 5615  C CB  . VAL B 1 404 ? -11.129 -9.047  61.444  1.00 71.79  ? 404 VAL B CB  1 
ATOM 5616  C CG1 . VAL B 1 404 ? -10.782 -9.505  60.036  1.00 79.59  ? 404 VAL B CG1 1 
ATOM 5617  C CG2 . VAL B 1 404 ? -9.899  -8.492  62.144  1.00 66.99  ? 404 VAL B CG2 1 
ATOM 5618  N N   . ILE B 1 405 ? -14.215 -9.537  61.382  1.00 73.76  ? 405 ILE B N   1 
ATOM 5619  C CA  . ILE B 1 405 ? -15.362 -10.205 60.705  1.00 67.89  ? 405 ILE B CA  1 
ATOM 5620  C C   . ILE B 1 405 ? -16.457 -9.187  60.366  1.00 62.60  ? 405 ILE B C   1 
ATOM 5621  O O   . ILE B 1 405 ? -16.947 -9.181  59.209  1.00 64.76  ? 405 ILE B O   1 
ATOM 5622  C CB  . ILE B 1 405 ? -15.851 -11.337 61.624  1.00 56.81  ? 405 ILE B CB  1 
ATOM 5623  C CG1 . ILE B 1 405 ? -14.735 -12.344 61.904  1.00 60.80  ? 405 ILE B CG1 1 
ATOM 5624  C CG2 . ILE B 1 405 ? -17.095 -12.012 61.077  1.00 59.73  ? 405 ILE B CG2 1 
ATOM 5625  C CD1 . ILE B 1 405 ? -15.086 -13.371 62.947  1.00 70.83  ? 405 ILE B CD1 1 
ATOM 5626  N N   . ARG B 1 406 ? -16.781 -8.314  61.310  1.00 55.78  ? 406 ARG B N   1 
ATOM 5627  C CA  . ARG B 1 406 ? -17.892 -7.358  61.095  1.00 64.55  ? 406 ARG B CA  1 
ATOM 5628  C C   . ARG B 1 406 ? -17.544 -6.382  59.977  1.00 64.51  ? 406 ARG B C   1 
ATOM 5629  O O   . ARG B 1 406 ? -18.419 -6.109  59.083  1.00 78.51  ? 406 ARG B O   1 
ATOM 5630  C CB  . ARG B 1 406 ? -18.172 -6.650  62.419  1.00 67.53  ? 406 ARG B CB  1 
ATOM 5631  C CG  . ARG B 1 406 ? -18.579 -7.584  63.550  1.00 67.31  ? 406 ARG B CG  1 
ATOM 5632  C CD  . ARG B 1 406 ? -19.101 -6.827  64.755  1.00 62.51  ? 406 ARG B CD  1 
ATOM 5633  N NE  . ARG B 1 406 ? -18.099 -5.946  65.332  1.00 70.76  ? 406 ARG B NE  1 
ATOM 5634  C CZ  . ARG B 1 406 ? -17.430 -6.194  66.450  1.00 78.25  ? 406 ARG B CZ  1 
ATOM 5635  N NH1 . ARG B 1 406 ? -17.669 -7.295  67.133  1.00 76.90  ? 406 ARG B NH1 1 
ATOM 5636  N NH2 . ARG B 1 406 ? -16.534 -5.330  66.889  1.00 82.01  ? 406 ARG B NH2 1 
ATOM 5637  N N   . ARG B 1 407 ? -16.321 -5.844  60.006  1.00 59.81  ? 407 ARG B N   1 
ATOM 5638  C CA  . ARG B 1 407 ? -15.882 -4.869  58.972  1.00 68.33  ? 407 ARG B CA  1 
ATOM 5639  C C   . ARG B 1 407 ? -16.025 -5.506  57.588  1.00 71.52  ? 407 ARG B C   1 
ATOM 5640  O O   . ARG B 1 407 ? -16.586 -4.847  56.692  1.00 72.18  ? 407 ARG B O   1 
ATOM 5641  C CB  . ARG B 1 407 ? -14.436 -4.444  59.237  1.00 82.60  ? 407 ARG B CB  1 
ATOM 5642  C CG  . ARG B 1 407 ? -13.846 -3.524  58.179  1.00 82.00  ? 407 ARG B CG  1 
ATOM 5643  C CD  . ARG B 1 407 ? -12.391 -3.172  58.428  1.00 93.06  ? 407 ARG B CD  1 
ATOM 5644  N NE  . ARG B 1 407 ? -11.488 -4.313  58.353  1.00 91.23  ? 407 ARG B NE  1 
ATOM 5645  C CZ  . ARG B 1 407 ? -10.973 -4.945  59.403  1.00 96.44  ? 407 ARG B CZ  1 
ATOM 5646  N NH1 . ARG B 1 407 ? -11.265 -4.546  60.630  1.00 98.01  ? 407 ARG B NH1 1 
ATOM 5647  N NH2 . ARG B 1 407 ? -10.162 -5.971  59.222  1.00 99.39  ? 407 ARG B NH2 1 
ATOM 5648  N N   . LYS B 1 408 ? -15.568 -6.749  57.453  1.00 66.58  ? 408 LYS B N   1 
ATOM 5649  C CA  . LYS B 1 408 ? -15.592 -7.435  56.141  1.00 61.77  ? 408 LYS B CA  1 
ATOM 5650  C C   . LYS B 1 408 ? -17.031 -7.629  55.675  1.00 64.27  ? 408 LYS B C   1 
ATOM 5651  O O   . LYS B 1 408 ? -17.284 -7.435  54.484  1.00 70.45  ? 408 LYS B O   1 
ATOM 5652  C CB  . LYS B 1 408 ? -14.894 -8.788  56.251  1.00 66.64  ? 408 LYS B CB  1 
ATOM 5653  C CG  . LYS B 1 408 ? -13.425 -8.748  56.651  1.00 73.41  ? 408 LYS B CG  1 
ATOM 5654  C CD  . LYS B 1 408 ? -12.521 -8.050  55.655  1.00 89.31  ? 408 LYS B CD  1 
ATOM 5655  C CE  . LYS B 1 408 ? -11.061 -8.090  56.059  1.00 88.40  ? 408 LYS B CE  1 
ATOM 5656  N NZ  . LYS B 1 408 ? -10.185 -7.433  55.060  1.00 106.60 ? 408 LYS B NZ  1 
ATOM 5657  N N   . ALA B 1 409 ? -17.925 -8.006  56.579  1.00 57.60  ? 409 ALA B N   1 
ATOM 5658  C CA  . ALA B 1 409 ? -19.340 -8.267  56.223  1.00 60.08  ? 409 ALA B CA  1 
ATOM 5659  C C   . ALA B 1 409 ? -19.960 -7.002  55.619  1.00 64.64  ? 409 ALA B C   1 
ATOM 5660  O O   . ALA B 1 409 ? -20.663 -7.124  54.598  1.00 69.38  ? 409 ALA B O   1 
ATOM 5661  C CB  . ALA B 1 409 ? -20.101 -8.737  57.436  1.00 57.25  ? 409 ALA B CB  1 
ATOM 5662  N N   . ARG B 1 410 ? -19.646 -5.853  56.207  1.00 54.58  ? 410 ARG B N   1 
ATOM 5663  C CA  . ARG B 1 410 ? -20.243 -4.584  55.741  1.00 65.12  ? 410 ARG B CA  1 
ATOM 5664  C C   . ARG B 1 410 ? -19.630 -4.208  54.402  1.00 64.05  ? 410 ARG B C   1 
ATOM 5665  O O   . ARG B 1 410 ? -20.376 -3.845  53.493  1.00 69.44  ? 410 ARG B O   1 
ATOM 5666  C CB  . ARG B 1 410 ? -19.938 -3.484  56.755  1.00 65.42  ? 410 ARG B CB  1 
ATOM 5667  C CG  . ARG B 1 410 ? -20.395 -2.094  56.337  1.00 70.15  ? 410 ARG B CG  1 
ATOM 5668  C CD  . ARG B 1 410 ? -19.732 -1.013  57.166  1.00 73.85  ? 410 ARG B CD  1 
ATOM 5669  N NE  . ARG B 1 410 ? -19.806 -1.311  58.589  1.00 67.28  ? 410 ARG B NE  1 
ATOM 5670  C CZ  . ARG B 1 410 ? -18.765 -1.331  59.414  1.00 66.88  ? 410 ARG B CZ  1 
ATOM 5671  N NH1 . ARG B 1 410 ? -17.552 -1.072  58.958  1.00 63.76  ? 410 ARG B NH1 1 
ATOM 5672  N NH2 . ARG B 1 410 ? -18.941 -1.617  60.691  1.00 68.59  ? 410 ARG B NH2 1 
ATOM 5673  N N   . GLU B 1 411 ? -18.317 -4.313  54.299  1.00 65.23  ? 411 GLU B N   1 
ATOM 5674  C CA  . GLU B 1 411 ? -17.619 -3.889  53.064  1.00 64.88  ? 411 GLU B CA  1 
ATOM 5675  C C   . GLU B 1 411 ? -18.101 -4.767  51.909  1.00 71.83  ? 411 GLU B C   1 
ATOM 5676  O O   . GLU B 1 411 ? -18.421 -4.236  50.828  1.00 72.57  ? 411 GLU B O   1 
ATOM 5677  C CB  . GLU B 1 411 ? -16.110 -3.927  53.296  1.00 64.53  ? 411 GLU B CB  1 
ATOM 5678  C CG  . GLU B 1 411 ? -15.595 -2.717  54.050  1.00 85.33  ? 411 GLU B CG  1 
ATOM 5679  C CD  . GLU B 1 411 ? -14.119 -2.776  54.401  1.00 94.99  ? 411 GLU B CD  1 
ATOM 5680  O OE1 . GLU B 1 411 ? -13.538 -3.870  54.307  1.00 95.20  ? 411 GLU B OE1 1 
ATOM 5681  O OE2 . GLU B 1 411 ? -13.555 -1.726  54.766  1.00 94.68  ? 411 GLU B OE2 1 
ATOM 5682  N N   . LEU B 1 412 ? -18.223 -6.062  52.168  1.00 70.78  ? 412 LEU B N   1 
ATOM 5683  C CA  . LEU B 1 412 ? -18.689 -6.986  51.111  1.00 73.09  ? 412 LEU B CA  1 
ATOM 5684  C C   . LEU B 1 412 ? -20.138 -6.666  50.739  1.00 67.76  ? 412 LEU B C   1 
ATOM 5685  O O   . LEU B 1 412 ? -20.458 -6.789  49.564  1.00 68.57  ? 412 LEU B O   1 
ATOM 5686  C CB  . LEU B 1 412 ? -18.464 -8.432  51.556  1.00 67.83  ? 412 LEU B CB  1 
ATOM 5687  C CG  . LEU B 1 412 ? -17.004 -8.880  51.537  1.00 68.40  ? 412 LEU B CG  1 
ATOM 5688  C CD1 . LEU B 1 412 ? -16.905 -10.392 51.499  1.00 68.82  ? 412 LEU B CD1 1 
ATOM 5689  C CD2 . LEU B 1 412 ? -16.270 -8.285  50.347  1.00 76.45  ? 412 LEU B CD2 1 
ATOM 5690  N N   . SER B 1 413 ? -20.976 -6.295  51.708  1.00 66.27  ? 413 SER B N   1 
ATOM 5691  C CA  . SER B 1 413 ? -22.395 -5.929  51.455  1.00 68.62  ? 413 SER B CA  1 
ATOM 5692  C C   . SER B 1 413 ? -22.444 -4.683  50.588  1.00 71.15  ? 413 SER B C   1 
ATOM 5693  O O   . SER B 1 413 ? -23.238 -4.640  49.638  1.00 83.58  ? 413 SER B O   1 
ATOM 5694  C CB  . SER B 1 413 ? -23.122 -5.693  52.742  1.00 65.19  ? 413 SER B CB  1 
ATOM 5695  O OG  . SER B 1 413 ? -24.429 -5.199  52.500  1.00 77.03  ? 413 SER B OG  1 
ATOM 5696  N N   . GLU B 1 414 ? -21.571 -3.732  50.890  1.00 64.96  ? 414 GLU B N   1 
ATOM 5697  C CA  . GLU B 1 414 ? -21.520 -2.491  50.098  1.00 68.29  ? 414 GLU B CA  1 
ATOM 5698  C C   . GLU B 1 414 ? -21.142 -2.880  48.678  1.00 69.00  ? 414 GLU B C   1 
ATOM 5699  O O   . GLU B 1 414 ? -21.756 -2.354  47.768  1.00 70.80  ? 414 GLU B O   1 
ATOM 5700  C CB  . GLU B 1 414 ? -20.497 -1.531  50.700  1.00 67.67  ? 414 GLU B CB  1 
ATOM 5701  C CG  . GLU B 1 414 ? -20.976 -0.860  51.970  1.00 68.18  ? 414 GLU B CG  1 
ATOM 5702  C CD  . GLU B 1 414 ? -19.942 0.030   52.633  1.00 90.11  ? 414 GLU B CD  1 
ATOM 5703  O OE1 . GLU B 1 414 ? -18.740 -0.258  52.492  1.00 90.05  ? 414 GLU B OE1 1 
ATOM 5704  O OE2 . GLU B 1 414 ? -20.343 1.016   53.278  1.00 98.59  ? 414 GLU B OE2 1 
ATOM 5705  N N   . LYS B 1 415 ? -20.184 -3.792  48.523  1.00 65.42  ? 415 LYS B N   1 
ATOM 5706  C CA  . LYS B 1 415 ? -19.737 -4.185  47.166  1.00 69.53  ? 415 LYS B CA  1 
ATOM 5707  C C   . LYS B 1 415 ? -20.886 -4.865  46.434  1.00 70.25  ? 415 LYS B C   1 
ATOM 5708  O O   . LYS B 1 415 ? -21.101 -4.556  45.262  1.00 73.69  ? 415 LYS B O   1 
ATOM 5709  C CB  . LYS B 1 415 ? -18.557 -5.149  47.235  1.00 71.28  ? 415 LYS B CB  1 
ATOM 5710  C CG  . LYS B 1 415 ? -17.187 -4.503  47.366  1.00 73.26  ? 415 LYS B CG  1 
ATOM 5711  C CD  . LYS B 1 415 ? -16.121 -5.464  47.840  1.00 74.39  ? 415 LYS B CD  1 
ATOM 5712  C CE  . LYS B 1 415 ? -14.741 -4.848  47.840  1.00 71.72  ? 415 LYS B CE  1 
ATOM 5713  N NZ  . LYS B 1 415 ? -14.751 -3.495  48.445  1.00 81.85  ? 415 LYS B NZ  1 
ATOM 5714  N N   . MET B 1 416 ? -21.610 -5.733  47.120  1.00 71.87  ? 416 MET B N   1 
ATOM 5715  C CA  . MET B 1 416 ? -22.671 -6.508  46.445  1.00 71.76  ? 416 MET B CA  1 
ATOM 5716  C C   . MET B 1 416 ? -23.714 -5.515  45.961  1.00 75.56  ? 416 MET B C   1 
ATOM 5717  O O   . MET B 1 416 ? -24.345 -5.776  44.932  1.00 79.92  ? 416 MET B O   1 
ATOM 5718  C CB  . MET B 1 416 ? -23.266 -7.528  47.417  1.00 63.69  ? 416 MET B CB  1 
ATOM 5719  C CG  . MET B 1 416 ? -22.326 -8.672  47.724  1.00 72.25  ? 416 MET B CG  1 
ATOM 5720  S SD  . MET B 1 416 ? -22.913 -9.691  49.089  1.00 67.31  ? 416 MET B SD  1 
ATOM 5721  C CE  . MET B 1 416 ? -24.465 -10.269 48.411  1.00 53.33  ? 416 MET B CE  1 
ATOM 5722  N N   . LYS B 1 417 ? -23.871 -4.416  46.680  1.00 69.75  ? 417 LYS B N   1 
ATOM 5723  C CA  . LYS B 1 417 ? -24.767 -3.364  46.232  1.00 75.95  ? 417 LYS B CA  1 
ATOM 5724  C C   . LYS B 1 417 ? -24.060 -2.269  45.447  1.00 78.02  ? 417 LYS B C   1 
ATOM 5725  O O   . LYS B 1 417 ? -24.732 -1.484  44.768  1.00 75.69  ? 417 LYS B O   1 
ATOM 5726  C CB  . LYS B 1 417 ? -25.497 -2.740  47.426  1.00 67.86  ? 417 LYS B CB  1 
ATOM 5727  C CG  . LYS B 1 417 ? -26.387 -3.715  48.182  1.00 85.53  ? 417 LYS B CG  1 
ATOM 5728  C CD  . LYS B 1 417 ? -27.458 -4.310  47.272  1.00 91.79  ? 417 LYS B CD  1 
ATOM 5729  C CE  . LYS B 1 417 ? -28.401 -3.237  46.739  1.00 97.30  ? 417 LYS B CE  1 
ATOM 5730  N NZ  . LYS B 1 417 ? -29.465 -3.809  45.868  1.00 87.86  ? 417 LYS B NZ  1 
ATOM 5731  N N   . GLU B 1 418 ? -22.729 -2.201  45.515  1.00 77.52  ? 418 GLU B N   1 
ATOM 5732  C CA  . GLU B 1 418 ? -22.002 -1.196  44.749  1.00 80.38  ? 418 GLU B CA  1 
ATOM 5733  C C   . GLU B 1 418 ? -21.945 -1.568  43.271  1.00 79.62  ? 418 GLU B C   1 
ATOM 5734  O O   . GLU B 1 418 ? -22.207 -0.730  42.401  1.00 81.47  ? 418 GLU B O   1 
ATOM 5735  C CB  . GLU B 1 418 ? -20.597 -1.010  45.324  1.00 84.68  ? 418 GLU B CB  1 
ATOM 5736  C CG  . GLU B 1 418 ? -19.946 0.309   44.953  1.00 94.59  ? 418 GLU B CG  1 
ATOM 5737  C CD  . GLU B 1 418 ? -18.809 0.680   45.886  1.00 98.92  ? 418 GLU B CD  1 
ATOM 5738  O OE1 . GLU B 1 418 ? -18.414 -0.168  46.714  1.00 98.66  ? 418 GLU B OE1 1 
ATOM 5739  O OE2 . GLU B 1 418 ? -18.313 1.823   45.793  1.00 105.65 ? 418 GLU B OE2 1 
ATOM 5740  N N   . LYS B 1 419 ? -21.817 -2.869  42.992  1.00 82.31  ? 419 LYS B N   1 
ATOM 5741  C CA  . LYS B 1 419 ? -21.862 -3.359  41.586  1.00 80.09  ? 419 LYS B CA  1 
ATOM 5742  C C   . LYS B 1 419 ? -23.275 -3.859  41.293  1.00 79.59  ? 419 LYS B C   1 
ATOM 5743  O O   . LYS B 1 419 ? -23.411 -4.885  40.608  1.00 78.81  ? 419 LYS B O   1 
ATOM 5744  C CB  . LYS B 1 419 ? -20.843 -4.484  41.391  1.00 73.59  ? 419 LYS B CB  1 
ATOM 5745  C CG  . LYS B 1 419 ? -20.994 -5.686  42.316  1.00 77.19  ? 419 LYS B CG  1 
ATOM 5746  C CD  . LYS B 1 419 ? -20.105 -6.846  41.936  1.00 77.61  ? 419 LYS B CD  1 
ATOM 5747  C CE  . LYS B 1 419 ? -20.651 -8.180  42.395  1.00 89.76  ? 419 LYS B CE  1 
ATOM 5748  N NZ  . LYS B 1 419 ? -20.932 -8.186  43.848  1.00 82.37  ? 419 LYS B NZ  1 
ATOM 5749  N N   . GLY B 1 420 ? -24.290 -3.123  41.733  1.00 78.21  ? 420 GLY B N   1 
ATOM 5750  C CA  . GLY B 1 420 ? -25.678 -3.612  41.632  1.00 82.50  ? 420 GLY B CA  1 
ATOM 5751  C C   . GLY B 1 420 ? -26.305 -3.658  40.262  1.00 82.55  ? 420 GLY B C   1 
ATOM 5752  O O   . GLY B 1 420 ? -26.047 -2.725  39.492  1.00 83.36  ? 420 GLY B O   1 
ATOM 5753  N N   . GLU B 1 421 ? -27.028 -4.737  39.948  1.00 82.41  ? 421 GLU B N   1 
ATOM 5754  C CA  . GLU B 1 421 ? -27.827 -4.864  38.696  1.00 58.94  ? 421 GLU B CA  1 
ATOM 5755  C C   . GLU B 1 421 ? -26.973 -5.248  37.490  1.00 65.79  ? 421 GLU B C   1 
ATOM 5756  O O   . GLU B 1 421 ? -27.505 -5.881  36.583  1.00 73.74  ? 421 GLU B O   1 
ATOM 5757  C CB  . GLU B 1 421 ? -28.724 -3.648  38.448  1.00 58.20  ? 421 GLU B CB  1 
ATOM 5758  C CG  . GLU B 1 421 ? -29.780 -3.429  39.520  1.00 83.42  ? 421 GLU B CG  1 
ATOM 5759  C CD  . GLU B 1 421 ? -30.935 -4.418  39.609  1.00 84.80  ? 421 GLU B CD  1 
ATOM 5760  O OE1 . GLU B 1 421 ? -30.714 -5.629  39.419  1.00 76.24  ? 421 GLU B OE1 1 
ATOM 5761  O OE2 . GLU B 1 421 ? -32.061 -3.972  39.894  1.00 81.89  ? 421 GLU B OE2 1 
ATOM 5762  N N   . GLN B 1 422 ? -25.682 -4.962  37.542  1.00 69.54  ? 422 GLN B N   1 
ATOM 5763  C CA  . GLN B 1 422 ? -24.797 -5.253  36.395  1.00 64.46  ? 422 GLN B CA  1 
ATOM 5764  C C   . GLN B 1 422 ? -24.685 -6.756  36.187  1.00 64.30  ? 422 GLN B C   1 
ATOM 5765  O O   . GLN B 1 422 ? -24.676 -7.168  35.034  1.00 66.08  ? 422 GLN B O   1 
ATOM 5766  C CB  . GLN B 1 422 ? -23.406 -4.668  36.612  1.00 78.45  ? 422 GLN B CB  1 
ATOM 5767  C CG  . GLN B 1 422 ? -23.403 -3.341  37.358  1.00 84.07  ? 422 GLN B CG  1 
ATOM 5768  C CD  . GLN B 1 422 ? -24.052 -2.218  36.588  1.00 85.75  ? 422 GLN B CD  1 
ATOM 5769  O OE1 . GLN B 1 422 ? -24.063 -2.205  35.359  1.00 86.82  ? 422 GLN B OE1 1 
ATOM 5770  N NE2 . GLN B 1 422 ? -24.589 -1.251  37.314  1.00 82.78  ? 422 GLN B NE2 1 
ATOM 5771  N N   . GLU B 1 423 ? -24.586 -7.538  37.258  1.00 60.12  ? 423 GLU B N   1 
ATOM 5772  C CA  . GLU B 1 423 ? -24.329 -8.989  37.067  1.00 60.29  ? 423 GLU B CA  1 
ATOM 5773  C C   . GLU B 1 423 ? -25.476 -9.659  36.323  1.00 56.05  ? 423 GLU B C   1 
ATOM 5774  O O   . GLU B 1 423 ? -25.190 -10.406 35.387  1.00 54.10  ? 423 GLU B O   1 
ATOM 5775  C CB  . GLU B 1 423 ? -23.985 -9.663  38.397  1.00 65.75  ? 423 GLU B CB  1 
ATOM 5776  C CG  . GLU B 1 423 ? -24.608 -9.023  39.626  1.00 73.21  ? 423 GLU B CG  1 
ATOM 5777  C CD  . GLU B 1 423 ? -24.152 -9.646  40.939  1.00 72.90  ? 423 GLU B CD  1 
ATOM 5778  O OE1 . GLU B 1 423 ? -23.230 -10.486 40.905  1.00 59.72  ? 423 GLU B OE1 1 
ATOM 5779  O OE2 . GLU B 1 423 ? -24.715 -9.290  41.995  1.00 80.94  ? 423 GLU B OE2 1 
ATOM 5780  N N   . ILE B 1 424 ? -26.710 -9.382  36.715  1.00 52.33  ? 424 ILE B N   1 
ATOM 5781  C CA  . ILE B 1 424 ? -27.894 -9.918  35.989  1.00 49.13  ? 424 ILE B CA  1 
ATOM 5782  C C   . ILE B 1 424 ? -27.987 -9.258  34.611  1.00 52.42  ? 424 ILE B C   1 
ATOM 5783  O O   . ILE B 1 424 ? -28.428 -9.925  33.675  1.00 58.16  ? 424 ILE B O   1 
ATOM 5784  C CB  . ILE B 1 424 ? -29.165 -9.796  36.842  1.00 48.74  ? 424 ILE B CB  1 
ATOM 5785  C CG1 . ILE B 1 424 ? -28.882 -10.180 38.295  1.00 49.82  ? 424 ILE B CG1 1 
ATOM 5786  C CG2 . ILE B 1 424 ? -30.293 -10.627 36.257  1.00 51.82  ? 424 ILE B CG2 1 
ATOM 5787  C CD1 . ILE B 1 424 ? -30.118 -10.320 39.142  1.00 57.23  ? 424 ILE B CD1 1 
ATOM 5788  N N   . ASP B 1 425 ? -27.608 -7.987  34.505  1.00 49.94  ? 425 ASP B N   1 
ATOM 5789  C CA  . ASP B 1 425 ? -27.607 -7.293  33.193  1.00 51.67  ? 425 ASP B CA  1 
ATOM 5790  C C   . ASP B 1 425 ? -26.618 -7.969  32.244  1.00 55.30  ? 425 ASP B C   1 
ATOM 5791  O O   . ASP B 1 425 ? -26.978 -8.180  31.083  1.00 58.13  ? 425 ASP B O   1 
ATOM 5792  C CB  . ASP B 1 425 ? -27.231 -5.823  33.361  1.00 56.82  ? 425 ASP B CB  1 
ATOM 5793  C CG  . ASP B 1 425 ? -28.352 -4.932  33.861  1.00 65.36  ? 425 ASP B CG  1 
ATOM 5794  O OD1 . ASP B 1 425 ? -29.382 -5.471  34.289  1.00 63.78  ? 425 ASP B OD1 1 
ATOM 5795  O OD2 . ASP B 1 425 ? -28.175 -3.702  33.824  1.00 69.50  ? 425 ASP B OD2 1 
ATOM 5796  N N   . ARG B 1 426 ? -25.418 -8.282  32.723  1.00 53.92  ? 426 ARG B N   1 
ATOM 5797  C CA  . ARG B 1 426 ? -24.407 -9.001  31.909  1.00 58.50  ? 426 ARG B CA  1 
ATOM 5798  C C   . ARG B 1 426 ? -24.901 -10.411 31.601  1.00 50.77  ? 426 ARG B C   1 
ATOM 5799  O O   . ARG B 1 426 ? -24.563 -10.935 30.537  1.00 52.17  ? 426 ARG B O   1 
ATOM 5800  C CB  . ARG B 1 426 ? -23.063 -8.984  32.635  1.00 64.48  ? 426 ARG B CB  1 
ATOM 5801  C CG  . ARG B 1 426 ? -22.459 -7.595  32.778  1.00 78.05  ? 426 ARG B CG  1 
ATOM 5802  C CD  . ARG B 1 426 ? -21.073 -7.623  33.389  1.00 84.52  ? 426 ARG B CD  1 
ATOM 5803  N NE  . ARG B 1 426 ? -21.015 -8.539  34.518  1.00 89.62  ? 426 ARG B NE  1 
ATOM 5804  C CZ  . ARG B 1 426 ? -19.933 -8.760  35.251  1.00 90.38  ? 426 ARG B CZ  1 
ATOM 5805  N NH1 . ARG B 1 426 ? -18.807 -8.123  34.977  1.00 75.48  ? 426 ARG B NH1 1 
ATOM 5806  N NH2 . ARG B 1 426 ? -19.980 -9.616  36.257  1.00 93.51  ? 426 ARG B NH2 1 
ATOM 5807  N N   . ALA B 1 427 ? -25.595 -11.033 32.549  1.00 48.51  ? 427 ALA B N   1 
ATOM 5808  C CA  . ALA B 1 427 ? -26.160 -12.380 32.334  1.00 49.74  ? 427 ALA B CA  1 
ATOM 5809  C C   . ALA B 1 427 ? -27.205 -12.307 31.234  1.00 51.33  ? 427 ALA B C   1 
ATOM 5810  O O   . ALA B 1 427 ? -27.228 -13.201 30.390  1.00 50.45  ? 427 ALA B O   1 
ATOM 5811  C CB  . ALA B 1 427 ? -26.797 -12.852 33.604  1.00 50.53  ? 427 ALA B CB  1 
ATOM 5812  N N   . VAL B 1 428 ? -28.037 -11.270 31.264  1.00 45.04  ? 428 VAL B N   1 
ATOM 5813  C CA  . VAL B 1 428 ? -29.071 -11.135 30.242  1.00 47.14  ? 428 VAL B CA  1 
ATOM 5814  C C   . VAL B 1 428 ? -28.447 -10.897 28.876  1.00 52.88  ? 428 VAL B C   1 
ATOM 5815  O O   . VAL B 1 428 ? -28.882 -11.473 27.872  1.00 52.31  ? 428 VAL B O   1 
ATOM 5816  C CB  . VAL B 1 428 ? -30.054 -10.013 30.615  1.00 50.68  ? 428 VAL B CB  1 
ATOM 5817  C CG1 . VAL B 1 428 ? -30.950 -9.673  29.431  1.00 49.90  ? 428 VAL B CG1 1 
ATOM 5818  C CG2 . VAL B 1 428 ? -30.889 -10.425 31.800  1.00 62.02  ? 428 VAL B CG2 1 
ATOM 5819  N N   . GLU B 1 429 ? -27.430 -10.037 28.806  1.00 53.13  ? 429 GLU B N   1 
ATOM 5820  C CA  . GLU B 1 429 ? -26.817 -9.799  27.506  1.00 48.34  ? 429 GLU B CA  1 
ATOM 5821  C C   . GLU B 1 429 ? -26.097 -11.047 26.998  1.00 47.00  ? 429 GLU B C   1 
ATOM 5822  O O   . GLU B 1 429 ? -26.089 -11.299 25.791  1.00 50.93  ? 429 GLU B O   1 
ATOM 5823  C CB  . GLU B 1 429 ? -25.877 -8.594  27.548  1.00 62.39  ? 429 GLU B CB  1 
ATOM 5824  C CG  . GLU B 1 429 ? -24.615 -8.769  28.358  1.00 65.61  ? 429 GLU B CG  1 
ATOM 5825  C CD  . GLU B 1 429 ? -23.762 -7.516  28.381  1.00 75.08  ? 429 GLU B CD  1 
ATOM 5826  O OE1 . GLU B 1 429 ? -23.855 -6.706  27.432  1.00 76.65  ? 429 GLU B OE1 1 
ATOM 5827  O OE2 . GLU B 1 429 ? -23.001 -7.337  29.353  1.00 85.40  ? 429 GLU B OE2 1 
ATOM 5828  N N   . GLU B 1 430 ? -25.544 -11.871 27.894  1.00 49.76  ? 430 GLU B N   1 
ATOM 5829  C CA  . GLU B 1 430 ? -24.935 -13.114 27.428  1.00 50.18  ? 430 GLU B CA  1 
ATOM 5830  C C   . GLU B 1 430 ? -25.988 -14.130 26.995  1.00 47.97  ? 430 GLU B C   1 
ATOM 5831  O O   . GLU B 1 430 ? -25.761 -14.876 26.036  1.00 49.34  ? 430 GLU B O   1 
ATOM 5832  C CB  . GLU B 1 430 ? -24.015 -13.709 28.497  1.00 52.38  ? 430 GLU B CB  1 
ATOM 5833  C CG  . GLU B 1 430 ? -22.864 -14.533 27.914  1.00 55.77  ? 430 GLU B CG  1 
ATOM 5834  C CD  . GLU B 1 430 ? -21.593 -14.463 28.753  1.00 69.01  ? 430 GLU B CD  1 
ATOM 5835  O OE1 . GLU B 1 430 ? -21.697 -14.241 29.982  1.00 64.74  ? 430 GLU B OE1 1 
ATOM 5836  O OE2 . GLU B 1 430 ? -20.487 -14.631 28.185  1.00 75.17  ? 430 GLU B OE2 1 
ATOM 5837  N N   . LEU B 1 431 ? -27.142 -14.164 27.665  1.00 50.60  ? 431 LEU B N   1 
ATOM 5838  C CA  . LEU B 1 431 ? -28.229 -15.023 27.193  1.00 40.13  ? 431 LEU B CA  1 
ATOM 5839  C C   . LEU B 1 431 ? -28.700 -14.600 25.804  1.00 43.94  ? 431 LEU B C   1 
ATOM 5840  O O   . LEU B 1 431 ? -28.932 -15.445 24.928  1.00 39.94  ? 431 LEU B O   1 
ATOM 5841  C CB  . LEU B 1 431 ? -29.392 -14.997 28.184  1.00 41.01  ? 431 LEU B CB  1 
ATOM 5842  C CG  . LEU B 1 431 ? -29.213 -15.765 29.498  1.00 44.72  ? 431 LEU B CG  1 
ATOM 5843  C CD1 . LEU B 1 431 ? -30.278 -15.375 30.516  1.00 44.48  ? 431 LEU B CD1 1 
ATOM 5844  C CD2 . LEU B 1 431 ? -29.234 -17.268 29.257  1.00 34.31  ? 431 LEU B CD2 1 
ATOM 5845  N N   . VAL B 1 432 ? -28.841 -13.291 25.586  1.00 44.30  ? 432 VAL B N   1 
ATOM 5846  C CA  . VAL B 1 432 ? -29.202 -12.792 24.262  1.00 48.07  ? 432 VAL B CA  1 
ATOM 5847  C C   . VAL B 1 432 ? -28.120 -13.132 23.248  1.00 49.12  ? 432 VAL B C   1 
ATOM 5848  O O   . VAL B 1 432 ? -28.412 -13.411 22.078  1.00 52.15  ? 432 VAL B O   1 
ATOM 5849  C CB  . VAL B 1 432 ? -29.474 -11.275 24.320  1.00 41.03  ? 432 VAL B CB  1 
ATOM 5850  C CG1 . VAL B 1 432 ? -29.769 -10.723 22.933  1.00 46.04  ? 432 VAL B CG1 1 
ATOM 5851  C CG2 . VAL B 1 432 ? -30.631 -10.986 25.259  1.00 41.46  ? 432 VAL B CG2 1 
ATOM 5852  N N   . GLN B 1 433 ? -26.853 -13.117 23.672  1.00 50.36  ? 433 GLN B N   1 
ATOM 5853  C CA  . GLN B 1 433 ? -25.779 -13.565 22.795  1.00 51.19  ? 433 GLN B CA  1 
ATOM 5854  C C   . GLN B 1 433 ? -25.959 -15.029 22.415  1.00 52.06  ? 433 GLN B C   1 
ATOM 5855  O O   . GLN B 1 433 ? -25.736 -15.409 21.261  1.00 59.32  ? 433 GLN B O   1 
ATOM 5856  C CB  . GLN B 1 433 ? -24.423 -13.343 23.466  1.00 56.04  ? 433 GLN B CB  1 
ATOM 5857  C CG  . GLN B 1 433 ? -23.229 -13.741 22.612  1.00 68.98  ? 433 GLN B CG  1 
ATOM 5858  C CD  . GLN B 1 433 ? -21.903 -13.458 23.295  1.00 79.50  ? 433 GLN B CD  1 
ATOM 5859  O OE1 . GLN B 1 433 ? -21.865 -12.955 24.419  1.00 78.42  ? 433 GLN B OE1 1 
ATOM 5860  N NE2 . GLN B 1 433 ? -20.806 -13.780 22.617  1.00 60.37  ? 433 GLN B NE2 1 
ATOM 5861  N N   . ILE B 1 434 ? -26.359 -15.868 23.371  1.00 55.66  ? 434 ILE B N   1 
ATOM 5862  C CA  . ILE B 1 434 ? -26.630 -17.271 23.055  1.00 53.30  ? 434 ILE B CA  1 
ATOM 5863  C C   . ILE B 1 434 ? -27.737 -17.364 22.009  1.00 59.92  ? 434 ILE B C   1 
ATOM 5864  O O   . ILE B 1 434 ? -27.624 -18.093 21.012  1.00 58.85  ? 434 ILE B O   1 
ATOM 5865  C CB  . ILE B 1 434 ? -26.993 -18.064 24.323  1.00 56.83  ? 434 ILE B CB  1 
ATOM 5866  C CG1 . ILE B 1 434 ? -25.883 -17.961 25.369  1.00 56.02  ? 434 ILE B CG1 1 
ATOM 5867  C CG2 . ILE B 1 434 ? -27.262 -19.522 23.979  1.00 50.53  ? 434 ILE B CG2 1 
ATOM 5868  C CD1 . ILE B 1 434 ? -24.504 -18.218 24.816  1.00 60.79  ? 434 ILE B CD1 1 
ATOM 5869  N N   . CYS B 1 435 ? -28.815 -16.605 22.218  1.00 63.82  ? 435 CYS B N   1 
ATOM 5870  C CA  . CYS B 1 435 ? -29.943 -16.660 21.292  1.00 64.41  ? 435 CYS B CA  1 
ATOM 5871  C C   . CYS B 1 435 ? -29.544 -16.211 19.888  1.00 65.84  ? 435 CYS B C   1 
ATOM 5872  O O   . CYS B 1 435 ? -29.961 -16.816 18.896  1.00 67.06  ? 435 CYS B O   1 
ATOM 5873  C CB  . CYS B 1 435 ? -31.104 -15.818 21.825  1.00 60.06  ? 435 CYS B CB  1 
ATOM 5874  S SG  . CYS B 1 435 ? -31.994 -16.588 23.198  1.00 61.70  ? 435 CYS B SG  1 
ATOM 5875  N N   . LYS B 1 436 ? -28.725 -15.159 19.783  1.00 60.61  ? 436 LYS B N   1 
ATOM 5876  C CA  . LYS B 1 436 ? -28.310 -14.700 18.458  1.00 61.52  ? 436 LYS B CA  1 
ATOM 5877  C C   . LYS B 1 436 ? -27.289 -15.642 17.832  1.00 56.02  ? 436 LYS B C   1 
ATOM 5878  O O   . LYS B 1 436 ? -27.207 -15.734 16.602  1.00 54.66  ? 436 LYS B O   1 
ATOM 5879  C CB  . LYS B 1 436 ? -27.749 -13.277 18.527  1.00 62.27  ? 436 LYS B CB  1 
ATOM 5880  C CG  . LYS B 1 436 ? -26.388 -13.179 19.187  1.00 60.27  ? 436 LYS B CG  1 
ATOM 5881  C CD  . LYS B 1 436 ? -25.730 -11.834 18.949  1.00 60.05  ? 436 LYS B CD  1 
ATOM 5882  C CE  . LYS B 1 436 ? -24.404 -11.748 19.703  1.00 69.38  ? 436 LYS B CE  1 
ATOM 5883  N NZ  . LYS B 1 436 ? -23.488 -12.872 19.355  1.00 66.72  ? 436 LYS B NZ  1 
ATOM 5884  N N   . LYS B 1 437 ? -26.508 -16.384 18.601  1.00 53.98  ? 437 LYS B N   1 
ATOM 5885  C CA  . LYS B 1 437 ? -25.581 -17.316 17.915  1.00 57.26  ? 437 LYS B CA  1 
ATOM 5886  C C   . LYS B 1 437 ? -26.422 -18.425 17.299  1.00 62.43  ? 437 LYS B C   1 
ATOM 5887  O O   . LYS B 1 437 ? -25.912 -19.140 16.428  1.00 67.77  ? 437 LYS B O   1 
ATOM 5888  C CB  . LYS B 1 437 ? -24.552 -17.893 18.884  1.00 55.04  ? 437 LYS B CB  1 
ATOM 5889  C CG  . LYS B 1 437 ? -23.373 -18.621 18.251  1.00 58.84  ? 437 LYS B CG  1 
ATOM 5890  C CD  . LYS B 1 437 ? -22.527 -19.375 19.252  1.00 69.36  ? 437 LYS B CD  1 
ATOM 5891  C CE  . LYS B 1 437 ? -23.303 -20.435 20.003  1.00 77.57  ? 437 LYS B CE  1 
ATOM 5892  N NZ  . LYS B 1 437 ? -23.793 -21.505 19.103  1.00 85.86  ? 437 LYS B NZ  1 
ATOM 5893  N N   . LYS B 1 438 ? -27.671 -18.548 17.737  1.00 69.20  ? 438 LYS B N   1 
ATOM 5894  C CA  . LYS B 1 438 ? -28.554 -19.629 17.225  1.00 71.45  ? 438 LYS B CA  1 
ATOM 5895  C C   . LYS B 1 438 ? -29.352 -19.115 16.028  1.00 65.89  ? 438 LYS B C   1 
ATOM 5896  O O   . LYS B 1 438 ? -30.104 -19.900 15.440  1.00 62.33  ? 438 LYS B O   1 
ATOM 5897  C CB  . LYS B 1 438 ? -29.406 -20.217 18.351  1.00 59.01  ? 438 LYS B CB  1 
ATOM 5898  C CG  . LYS B 1 438 ? -28.651 -21.072 19.359  1.00 64.85  ? 438 LYS B CG  1 
ATOM 5899  C CD  . LYS B 1 438 ? -28.392 -22.474 18.861  1.00 66.43  ? 438 LYS B CD  1 
ATOM 5900  C CE  . LYS B 1 438 ? -29.665 -23.211 18.504  1.00 62.29  ? 438 LYS B CE  1 
ATOM 5901  N NZ  . LYS B 1 438 ? -29.400 -24.623 18.147  1.00 63.43  ? 438 LYS B NZ  1 
ATOM 5902  N N   . LYS B 1 439 ? -29.185 -17.845 15.679  1.00 71.30  ? 439 LYS B N   1 
ATOM 5903  C CA  . LYS B 1 439 ? -29.832 -17.324 14.455  1.00 69.47  ? 439 LYS B CA  1 
ATOM 5904  C C   . LYS B 1 439 ? -28.921 -17.699 13.294  1.00 79.07  ? 439 LYS B C   1 
ATOM 5905  O O   . LYS B 1 439 ? -28.271 -16.803 12.743  1.00 80.03  ? 439 LYS B O   1 
ATOM 5906  C CB  . LYS B 1 439 ? -29.993 -15.808 14.546  1.00 72.47  ? 439 LYS B CB  1 
ATOM 5907  C CG  . LYS B 1 439 ? -31.134 -15.331 15.431  1.00 66.74  ? 439 LYS B CG  1 
ATOM 5908  C CD  . LYS B 1 439 ? -32.472 -15.890 15.000  1.00 80.47  ? 439 LYS B CD  1 
ATOM 5909  C CE  . LYS B 1 439 ? -32.841 -15.531 13.577  1.00 77.57  ? 439 LYS B CE  1 
ATOM 5910  N NZ  . LYS B 1 439 ? -34.051 -16.258 13.130  1.00 71.52  ? 439 LYS B NZ  1 
ATOM 5911  N N   . ASP B 1 440 ? -28.852 -18.990 12.974  1.00 83.10  ? 440 ASP B N   1 
ATOM 5912  C CA  . ASP B 1 440 ? -28.033 -19.477 11.839  1.00 77.74  ? 440 ASP B CA  1 
ATOM 5913  C C   . ASP B 1 440 ? -29.006 -20.042 10.807  1.00 81.99  ? 440 ASP B C   1 
ATOM 5914  O O   . ASP B 1 440 ? -29.867 -20.838 11.203  1.00 77.05  ? 440 ASP B O   1 
ATOM 5915  C CB  . ASP B 1 440 ? -26.976 -20.482 12.298  1.00 65.79  ? 440 ASP B CB  1 
ATOM 5916  C CG  . ASP B 1 440 ? -27.396 -21.408 13.430  1.00 74.60  ? 440 ASP B CG  1 
ATOM 5917  O OD1 . ASP B 1 440 ? -28.575 -21.801 13.470  1.00 83.26  ? 440 ASP B OD1 1 
ATOM 5918  O OD2 . ASP B 1 440 ? -26.532 -21.735 14.264  1.00 89.70  ? 440 ASP B OD2 1 
ATOM 5919  N N   . GLU B 1 441 ? -28.891 -19.618 9.547   1.00 88.85  ? 441 GLU B N   1 
ATOM 5920  C CA  . GLU B 1 441 ? -29.855 -20.038 8.503   1.00 85.29  ? 441 GLU B CA  1 
ATOM 5921  C C   . GLU B 1 441 ? -31.274 -19.673 8.937   1.00 92.38  ? 441 GLU B C   1 
ATOM 5922  O O   . GLU B 1 441 ? -32.156 -20.529 8.770   1.00 98.58  ? 441 GLU B O   1 
ATOM 5923  C CB  . GLU B 1 441 ? -29.740 -21.530 8.218   1.00 88.34  ? 441 GLU B CB  1 
ATOM 5924  C CG  . GLU B 1 441 ? -28.310 -22.004 8.008   1.00 91.54  ? 441 GLU B CG  1 
ATOM 5925  C CD  . GLU B 1 441 ? -27.636 -21.547 6.726   1.00 85.12  ? 441 GLU B CD  1 
ATOM 5926  O OE1 . GLU B 1 441 ? -27.284 -20.355 6.631   1.00 81.87  ? 441 GLU B OE1 1 
ATOM 5927  O OE2 . GLU B 1 441 ? -27.455 -22.394 5.829   1.00 75.55  ? 441 GLU B OE2 1 
ATOM 5928  N N   . GLN B 1 442 ? -31.475 -18.477 9.505   1.00 94.88  ? 442 GLN B N   1 
ATOM 5929  C CA  . GLN B 1 442 ? -32.836 -17.982 9.856   1.00 89.54  ? 442 GLN B CA  1 
ATOM 5930  C C   . GLN B 1 442 ? -33.583 -18.991 10.733  1.00 77.10  ? 442 GLN B C   1 
ATOM 5931  O O   . GLN B 1 442 ? -34.554 -18.556 11.381  1.00 90.00  ? 442 GLN B O   1 
ATOM 5932  C CB  . GLN B 1 442 ? -33.630 -17.657 8.589   1.00 95.04  ? 442 GLN B CB  1 
ATOM 5933  C CG  . GLN B 1 442 ? -32.993 -16.577 7.728   1.00 90.33  ? 442 GLN B CG  1 
ATOM 5934  C CD  . GLN B 1 442 ? -32.310 -17.146 6.508   1.00 82.89  ? 442 GLN B CD  1 
ATOM 5935  O OE1 . GLN B 1 442 ? -32.476 -18.314 6.168   1.00 62.48  ? 442 GLN B OE1 1 
ATOM 5936  N NE2 . GLN B 1 442 ? -31.535 -16.316 5.832   1.00 85.35  ? 442 GLN B NE2 1 
ATOM 5937  N N   . ILE C 1 8   ? -25.302 -64.839 -43.779 1.00 68.55  ? 8   ILE C N   1 
ATOM 5938  C CA  . ILE C 1 8   ? -24.474 -65.849 -43.133 1.00 71.76  ? 8   ILE C CA  1 
ATOM 5939  C C   . ILE C 1 8   ? -23.573 -65.217 -42.069 1.00 63.75  ? 8   ILE C C   1 
ATOM 5940  O O   . ILE C 1 8   ? -23.399 -65.777 -40.990 1.00 67.25  ? 8   ILE C O   1 
ATOM 5941  C CB  . ILE C 1 8   ? -23.637 -66.626 -44.173 1.00 76.89  ? 8   ILE C CB  1 
ATOM 5942  C CG1 . ILE C 1 8   ? -24.547 -67.261 -45.230 1.00 66.55  ? 8   ILE C CG1 1 
ATOM 5943  C CG2 . ILE C 1 8   ? -22.799 -67.700 -43.494 1.00 75.37  ? 8   ILE C CG2 1 
ATOM 5944  C CD1 . ILE C 1 8   ? -25.502 -68.298 -44.675 1.00 66.16  ? 8   ILE C CD1 1 
ATOM 5945  N N   . SER C 1 9   ? -23.006 -64.051 -42.369 1.00 58.32  ? 9   SER C N   1 
ATOM 5946  C CA  . SER C 1 9   ? -22.112 -63.361 -41.447 1.00 65.61  ? 9   SER C CA  1 
ATOM 5947  C C   . SER C 1 9   ? -22.869 -62.301 -40.659 1.00 60.41  ? 9   SER C C   1 
ATOM 5948  O O   . SER C 1 9   ? -23.660 -61.536 -41.221 1.00 55.50  ? 9   SER C O   1 
ATOM 5949  C CB  . SER C 1 9   ? -20.946 -62.709 -42.192 1.00 59.41  ? 9   SER C CB  1 
ATOM 5950  O OG  . SER C 1 9   ? -21.373 -61.545 -42.877 1.00 64.17  ? 9   SER C OG  1 
ATOM 5951  N N   . ILE C 1 10  ? -22.615 -62.251 -39.350 1.00 47.87  ? 10  ILE C N   1 
ATOM 5952  C CA  . ILE C 1 10  ? -23.292 -61.336 -38.440 1.00 51.08  ? 10  ILE C CA  1 
ATOM 5953  C C   . ILE C 1 10  ? -22.251 -60.623 -37.587 1.00 47.32  ? 10  ILE C C   1 
ATOM 5954  O O   . ILE C 1 10  ? -21.234 -61.218 -37.207 1.00 45.37  ? 10  ILE C O   1 
ATOM 5955  C CB  . ILE C 1 10  ? -24.311 -62.074 -37.540 1.00 46.94  ? 10  ILE C CB  1 
ATOM 5956  C CG1 . ILE C 1 10  ? -25.220 -62.980 -38.374 1.00 37.91  ? 10  ILE C CG1 1 
ATOM 5957  C CG2 . ILE C 1 10  ? -25.156 -61.084 -36.751 1.00 41.02  ? 10  ILE C CG2 1 
ATOM 5958  C CD1 . ILE C 1 10  ? -26.240 -63.736 -37.554 1.00 43.60  ? 10  ILE C CD1 1 
ATOM 5959  N N   . ALA C 1 11  ? -22.504 -59.350 -37.288 1.00 41.62  ? 11  ALA C N   1 
ATOM 5960  C CA  . ALA C 1 11  ? -21.668 -58.553 -36.403 1.00 43.29  ? 11  ALA C CA  1 
ATOM 5961  C C   . ALA C 1 11  ? -22.497 -58.072 -35.221 1.00 42.60  ? 11  ALA C C   1 
ATOM 5962  O O   . ALA C 1 11  ? -23.637 -57.629 -35.391 1.00 47.09  ? 11  ALA C O   1 
ATOM 5963  C CB  . ALA C 1 11  ? -21.060 -57.356 -37.143 1.00 38.33  ? 11  ALA C CB  1 
ATOM 5964  N N   . LEU C 1 12  ? -21.926 -58.162 -34.023 1.00 33.92  ? 12  LEU C N   1 
ATOM 5965  C CA  . LEU C 1 12  ? -22.611 -57.819 -32.785 1.00 33.94  ? 12  LEU C CA  1 
ATOM 5966  C C   . LEU C 1 12  ? -21.925 -56.630 -32.130 1.00 38.24  ? 12  LEU C C   1 
ATOM 5967  O O   . LEU C 1 12  ? -20.693 -56.593 -32.024 1.00 48.07  ? 12  LEU C O   1 
ATOM 5968  C CB  . LEU C 1 12  ? -22.636 -59.008 -31.818 1.00 33.83  ? 12  LEU C CB  1 
ATOM 5969  C CG  . LEU C 1 12  ? -23.908 -59.858 -31.825 1.00 38.88  ? 12  LEU C CG  1 
ATOM 5970  C CD1 . LEU C 1 12  ? -24.201 -60.363 -33.223 1.00 45.96  ? 12  LEU C CD1 1 
ATOM 5971  C CD2 . LEU C 1 12  ? -23.797 -61.017 -30.846 1.00 49.96  ? 12  LEU C CD2 1 
ATOM 5972  N N   . LEU C 1 13  ? -22.729 -55.657 -31.702 1.00 35.39  ? 13  LEU C N   1 
ATOM 5973  C CA  . LEU C 1 13  ? -22.243 -54.451 -31.036 1.00 36.45  ? 13  LEU C CA  1 
ATOM 5974  C C   . LEU C 1 13  ? -23.028 -54.269 -29.742 1.00 41.36  ? 13  LEU C C   1 
ATOM 5975  O O   . LEU C 1 13  ? -24.007 -53.512 -29.694 1.00 42.90  ? 13  LEU C O   1 
ATOM 5976  C CB  . LEU C 1 13  ? -22.379 -53.224 -31.936 1.00 37.40  ? 13  LEU C CB  1 
ATOM 5977  C CG  . LEU C 1 13  ? -21.858 -51.906 -31.365 1.00 50.74  ? 13  LEU C CG  1 
ATOM 5978  C CD1 . LEU C 1 13  ? -20.344 -51.807 -31.518 1.00 56.17  ? 13  LEU C CD1 1 
ATOM 5979  C CD2 . LEU C 1 13  ? -22.553 -50.726 -32.024 1.00 50.35  ? 13  LEU C CD2 1 
ATOM 5980  N N   . PRO C 1 14  ? -22.631 -54.960 -28.678 1.00 34.90  ? 14  PRO C N   1 
ATOM 5981  C CA  . PRO C 1 14  ? -23.268 -54.740 -27.376 1.00 43.51  ? 14  PRO C CA  1 
ATOM 5982  C C   . PRO C 1 14  ? -22.863 -53.396 -26.791 1.00 44.64  ? 14  PRO C C   1 
ATOM 5983  O O   . PRO C 1 14  ? -22.033 -52.666 -27.336 1.00 51.37  ? 14  PRO C O   1 
ATOM 5984  C CB  . PRO C 1 14  ? -22.745 -55.899 -26.526 1.00 40.10  ? 14  PRO C CB  1 
ATOM 5985  C CG  . PRO C 1 14  ? -21.436 -56.253 -27.153 1.00 36.50  ? 14  PRO C CG  1 
ATOM 5986  C CD  . PRO C 1 14  ? -21.607 -56.017 -28.623 1.00 37.64  ? 14  PRO C CD  1 
ATOM 5987  N N   . PHE C 1 15  ? -23.470 -53.071 -25.656 1.00 48.13  ? 15  PHE C N   1 
ATOM 5988  C CA  . PHE C 1 15  ? -23.122 -51.848 -24.954 1.00 48.94  ? 15  PHE C CA  1 
ATOM 5989  C C   . PHE C 1 15  ? -21.949 -52.101 -24.007 1.00 59.58  ? 15  PHE C C   1 
ATOM 5990  O O   . PHE C 1 15  ? -21.550 -53.242 -23.754 1.00 60.93  ? 15  PHE C O   1 
ATOM 5991  C CB  . PHE C 1 15  ? -24.332 -51.296 -24.202 1.00 45.43  ? 15  PHE C CB  1 
ATOM 5992  C CG  . PHE C 1 15  ? -24.157 -49.881 -23.740 1.00 43.83  ? 15  PHE C CG  1 
ATOM 5993  C CD1 . PHE C 1 15  ? -23.605 -48.929 -24.581 1.00 53.98  ? 15  PHE C CD1 1 
ATOM 5994  C CD2 . PHE C 1 15  ? -24.548 -49.498 -22.469 1.00 50.19  ? 15  PHE C CD2 1 
ATOM 5995  C CE1 . PHE C 1 15  ? -23.436 -47.624 -24.160 1.00 56.83  ? 15  PHE C CE1 1 
ATOM 5996  C CE2 . PHE C 1 15  ? -24.387 -48.193 -22.043 1.00 43.86  ? 15  PHE C CE2 1 
ATOM 5997  C CZ  . PHE C 1 15  ? -23.829 -47.255 -22.889 1.00 49.36  ? 15  PHE C CZ  1 
ATOM 5998  N N   . LEU C 1 16  ? -21.388 -51.014 -23.482 1.00 65.63  ? 16  LEU C N   1 
ATOM 5999  C CA  . LEU C 1 16  ? -20.186 -51.080 -22.650 1.00 65.74  ? 16  LEU C CA  1 
ATOM 6000  C C   . LEU C 1 16  ? -20.546 -51.366 -21.191 1.00 65.14  ? 16  LEU C C   1 
ATOM 6001  O O   . LEU C 1 16  ? -20.313 -50.567 -20.284 1.00 60.54  ? 16  LEU C O   1 
ATOM 6002  C CB  . LEU C 1 16  ? -19.382 -49.794 -22.782 1.00 68.03  ? 16  LEU C CB  1 
ATOM 6003  C CG  . LEU C 1 16  ? -18.244 -49.833 -23.800 1.00 69.85  ? 16  LEU C CG  1 
ATOM 6004  C CD1 . LEU C 1 16  ? -18.697 -50.489 -25.092 1.00 66.52  ? 16  LEU C CD1 1 
ATOM 6005  C CD2 . LEU C 1 16  ? -17.725 -48.431 -24.062 1.00 59.84  ? 16  LEU C CD2 1 
ATOM 6006  N N   . ALA C 1 17  ? -21.123 -52.544 -20.980 1.00 64.53  ? 17  ALA C N   1 
ATOM 6007  C CA  . ALA C 1 17  ? -21.490 -52.994 -19.647 1.00 58.49  ? 17  ALA C CA  1 
ATOM 6008  C C   . ALA C 1 17  ? -21.488 -54.513 -19.640 1.00 60.60  ? 17  ALA C C   1 
ATOM 6009  O O   . ALA C 1 17  ? -22.059 -55.139 -20.538 1.00 63.10  ? 17  ALA C O   1 
ATOM 6010  C CB  . ALA C 1 17  ? -22.866 -52.454 -19.240 1.00 49.37  ? 17  ALA C CB  1 
ATOM 6011  N N   . HIS C 1 18  ? -20.843 -55.097 -18.628 1.00 66.70  ? 18  HIS C N   1 
ATOM 6012  C CA  . HIS C 1 18  ? -20.749 -56.550 -18.548 1.00 70.25  ? 18  HIS C CA  1 
ATOM 6013  C C   . HIS C 1 18  ? -22.111 -57.213 -18.397 1.00 66.29  ? 18  HIS C C   1 
ATOM 6014  O O   . HIS C 1 18  ? -22.240 -58.411 -18.672 1.00 64.40  ? 18  HIS C O   1 
ATOM 6015  C CB  . HIS C 1 18  ? -19.826 -56.953 -17.396 1.00 76.09  ? 18  HIS C CB  1 
ATOM 6016  C CG  . HIS C 1 18  ? -18.387 -56.623 -17.637 1.00 85.35  ? 18  HIS C CG  1 
ATOM 6017  N ND1 . HIS C 1 18  ? -17.731 -55.612 -16.968 1.00 80.63  ? 18  HIS C ND1 1 
ATOM 6018  C CD2 . HIS C 1 18  ? -17.482 -57.158 -18.492 1.00 87.18  ? 18  HIS C CD2 1 
ATOM 6019  C CE1 . HIS C 1 18  ? -16.480 -55.547 -17.389 1.00 89.26  ? 18  HIS C CE1 1 
ATOM 6020  N NE2 . HIS C 1 18  ? -16.304 -56.476 -18.315 1.00 94.31  ? 18  HIS C NE2 1 
ATOM 6021  N N   . GLY C 1 19  ? -23.131 -56.463 -17.970 1.00 66.00  ? 19  GLY C N   1 
ATOM 6022  C CA  . GLY C 1 19  ? -24.483 -56.991 -17.970 1.00 65.66  ? 19  GLY C CA  1 
ATOM 6023  C C   . GLY C 1 19  ? -25.045 -57.230 -19.357 1.00 60.70  ? 19  GLY C C   1 
ATOM 6024  O O   . GLY C 1 19  ? -25.999 -58.001 -19.504 1.00 65.06  ? 19  GLY C O   1 
ATOM 6025  N N   . HIS C 1 20  ? -24.479 -56.581 -20.377 1.00 58.02  ? 20  HIS C N   1 
ATOM 6026  C CA  . HIS C 1 20  ? -24.889 -56.796 -21.756 1.00 57.76  ? 20  HIS C CA  1 
ATOM 6027  C C   . HIS C 1 20  ? -23.850 -57.536 -22.583 1.00 52.60  ? 20  HIS C C   1 
ATOM 6028  O O   . HIS C 1 20  ? -24.176 -58.001 -23.682 1.00 49.40  ? 20  HIS C O   1 
ATOM 6029  C CB  . HIS C 1 20  ? -25.217 -55.458 -22.436 1.00 58.18  ? 20  HIS C CB  1 
ATOM 6030  C CG  . HIS C 1 20  ? -26.411 -54.764 -21.859 1.00 54.60  ? 20  HIS C CG  1 
ATOM 6031  N ND1 . HIS C 1 20  ? -26.402 -54.181 -20.608 1.00 57.23  ? 20  HIS C ND1 1 
ATOM 6032  C CD2 . HIS C 1 20  ? -27.654 -54.565 -22.356 1.00 48.50  ? 20  HIS C CD2 1 
ATOM 6033  C CE1 . HIS C 1 20  ? -27.587 -53.649 -20.365 1.00 56.87  ? 20  HIS C CE1 1 
ATOM 6034  N NE2 . HIS C 1 20  ? -28.365 -53.868 -21.410 1.00 52.35  ? 20  HIS C NE2 1 
ATOM 6035  N N   . ILE C 1 21  ? -22.615 -57.660 -22.091 1.00 53.10  ? 21  ILE C N   1 
ATOM 6036  C CA  . ILE C 1 21  ? -21.600 -58.399 -22.829 1.00 47.69  ? 21  ILE C CA  1 
ATOM 6037  C C   . ILE C 1 21  ? -21.873 -59.896 -22.764 1.00 46.86  ? 21  ILE C C   1 
ATOM 6038  O O   . ILE C 1 21  ? -21.688 -60.621 -23.748 1.00 48.73  ? 21  ILE C O   1 
ATOM 6039  C CB  . ILE C 1 21  ? -20.197 -58.054 -22.294 1.00 51.50  ? 21  ILE C CB  1 
ATOM 6040  C CG1 . ILE C 1 21  ? -19.882 -56.580 -22.544 1.00 55.54  ? 21  ILE C CG1 1 
ATOM 6041  C CG2 . ILE C 1 21  ? -19.145 -58.928 -22.951 1.00 55.97  ? 21  ILE C CG2 1 
ATOM 6042  C CD1 . ILE C 1 21  ? -19.660 -56.252 -24.004 1.00 56.53  ? 21  ILE C CD1 1 
ATOM 6043  N N   . SER C 1 22  ? -22.326 -60.388 -21.605 1.00 45.42  ? 22  SER C N   1 
ATOM 6044  C CA  . SER C 1 22  ? -22.584 -61.821 -21.473 1.00 42.19  ? 22  SER C CA  1 
ATOM 6045  C C   . SER C 1 22  ? -23.729 -62.292 -22.361 1.00 40.95  ? 22  SER C C   1 
ATOM 6046  O O   . SER C 1 22  ? -23.555 -63.302 -23.065 1.00 35.40  ? 22  SER C O   1 
ATOM 6047  C CB  . SER C 1 22  ? -22.821 -62.177 -20.001 1.00 53.55  ? 22  SER C CB  1 
ATOM 6048  O OG  . SER C 1 22  ? -21.688 -61.864 -19.215 1.00 64.33  ? 22  SER C OG  1 
ATOM 6049  N N   . PRO C 1 23  ? -24.906 -61.649 -22.379 1.00 40.63  ? 23  PRO C N   1 
ATOM 6050  C CA  . PRO C 1 23  ? -25.965 -62.140 -23.279 1.00 41.17  ? 23  PRO C CA  1 
ATOM 6051  C C   . PRO C 1 23  ? -25.568 -62.089 -24.745 1.00 43.67  ? 23  PRO C C   1 
ATOM 6052  O O   . PRO C 1 23  ? -25.863 -63.028 -25.495 1.00 43.62  ? 23  PRO C O   1 
ATOM 6053  C CB  . PRO C 1 23  ? -27.146 -61.210 -22.973 1.00 49.58  ? 23  PRO C CB  1 
ATOM 6054  C CG  . PRO C 1 23  ? -26.874 -60.683 -21.610 1.00 44.14  ? 23  PRO C CG  1 
ATOM 6055  C CD  . PRO C 1 23  ? -25.388 -60.533 -21.546 1.00 45.04  ? 23  PRO C CD  1 
ATOM 6056  N N   . PHE C 1 24  ? -24.894 -61.018 -25.176 1.00 44.94  ? 24  PHE C N   1 
ATOM 6057  C CA  . PHE C 1 24  ? -24.429 -60.942 -26.555 1.00 41.16  ? 24  PHE C CA  1 
ATOM 6058  C C   . PHE C 1 24  ? -23.422 -62.044 -26.863 1.00 40.09  ? 24  PHE C C   1 
ATOM 6059  O O   . PHE C 1 24  ? -23.470 -62.653 -27.938 1.00 42.39  ? 24  PHE C O   1 
ATOM 6060  C CB  . PHE C 1 24  ? -23.819 -59.567 -26.829 1.00 44.89  ? 24  PHE C CB  1 
ATOM 6061  C CG  . PHE C 1 24  ? -24.817 -58.544 -27.300 1.00 38.62  ? 24  PHE C CG  1 
ATOM 6062  C CD1 . PHE C 1 24  ? -25.674 -57.927 -26.406 1.00 39.48  ? 24  PHE C CD1 1 
ATOM 6063  C CD2 . PHE C 1 24  ? -24.889 -58.201 -28.639 1.00 35.65  ? 24  PHE C CD2 1 
ATOM 6064  C CE1 . PHE C 1 24  ? -26.588 -56.985 -26.839 1.00 37.90  ? 24  PHE C CE1 1 
ATOM 6065  C CE2 . PHE C 1 24  ? -25.803 -57.261 -29.079 1.00 37.47  ? 24  PHE C CE2 1 
ATOM 6066  C CZ  . PHE C 1 24  ? -26.651 -56.651 -28.176 1.00 36.60  ? 24  PHE C CZ  1 
ATOM 6067  N N   . PHE C 1 25  ? -22.511 -62.330 -25.928 1.00 35.66  ? 25  PHE C N   1 
ATOM 6068  C CA  . PHE C 1 25  ? -21.513 -63.369 -26.164 1.00 36.58  ? 25  PHE C CA  1 
ATOM 6069  C C   . PHE C 1 25  ? -22.149 -64.750 -26.221 1.00 40.15  ? 25  PHE C C   1 
ATOM 6070  O O   . PHE C 1 25  ? -21.753 -65.592 -27.039 1.00 37.29  ? 25  PHE C O   1 
ATOM 6071  C CB  . PHE C 1 25  ? -20.437 -63.319 -25.081 1.00 40.52  ? 25  PHE C CB  1 
ATOM 6072  C CG  . PHE C 1 25  ? -19.452 -64.450 -25.153 1.00 48.12  ? 25  PHE C CG  1 
ATOM 6073  C CD1 . PHE C 1 25  ? -18.682 -64.641 -26.290 1.00 52.28  ? 25  PHE C CD1 1 
ATOM 6074  C CD2 . PHE C 1 25  ? -19.287 -65.316 -24.086 1.00 51.66  ? 25  PHE C CD2 1 
ATOM 6075  C CE1 . PHE C 1 25  ? -17.773 -65.679 -26.362 1.00 45.01  ? 25  PHE C CE1 1 
ATOM 6076  C CE2 . PHE C 1 25  ? -18.374 -66.354 -24.149 1.00 51.86  ? 25  PHE C CE2 1 
ATOM 6077  C CZ  . PHE C 1 25  ? -17.617 -66.535 -25.291 1.00 48.06  ? 25  PHE C CZ  1 
ATOM 6078  N N   . GLU C 1 26  ? -23.138 -65.007 -25.363 1.00 47.94  ? 26  GLU C N   1 
ATOM 6079  C CA  . GLU C 1 26  ? -23.818 -66.295 -25.398 1.00 52.92  ? 26  GLU C CA  1 
ATOM 6080  C C   . GLU C 1 26  ? -24.643 -66.448 -26.670 1.00 49.27  ? 26  GLU C C   1 
ATOM 6081  O O   . GLU C 1 26  ? -24.679 -67.531 -27.265 1.00 47.55  ? 26  GLU C O   1 
ATOM 6082  C CB  . GLU C 1 26  ? -24.695 -66.463 -24.155 1.00 49.88  ? 26  GLU C CB  1 
ATOM 6083  C CG  . GLU C 1 26  ? -23.902 -66.638 -22.865 1.00 51.78  ? 26  GLU C CG  1 
ATOM 6084  C CD  . GLU C 1 26  ? -23.064 -67.904 -22.857 1.00 63.20  ? 26  GLU C CD  1 
ATOM 6085  O OE1 . GLU C 1 26  ? -23.436 -68.873 -23.557 1.00 61.45  ? 26  GLU C OE1 1 
ATOM 6086  O OE2 . GLU C 1 26  ? -22.032 -67.936 -22.155 1.00 71.39  ? 26  GLU C OE2 1 
ATOM 6087  N N   . LEU C 1 27  ? -25.300 -65.371 -27.110 1.00 42.70  ? 27  LEU C N   1 
ATOM 6088  C CA  . LEU C 1 27  ? -25.985 -65.409 -28.398 1.00 44.93  ? 27  LEU C CA  1 
ATOM 6089  C C   . LEU C 1 27  ? -24.999 -65.652 -29.530 1.00 39.56  ? 27  LEU C C   1 
ATOM 6090  O O   . LEU C 1 27  ? -25.319 -66.346 -30.501 1.00 51.99  ? 27  LEU C O   1 
ATOM 6091  C CB  . LEU C 1 27  ? -26.754 -64.110 -28.629 1.00 44.06  ? 27  LEU C CB  1 
ATOM 6092  C CG  . LEU C 1 27  ? -27.555 -64.036 -29.930 1.00 36.96  ? 27  LEU C CG  1 
ATOM 6093  C CD1 . LEU C 1 27  ? -28.581 -65.158 -29.999 1.00 38.83  ? 27  LEU C CD1 1 
ATOM 6094  C CD2 . LEU C 1 27  ? -28.227 -62.683 -30.062 1.00 32.47  ? 27  LEU C CD2 1 
ATOM 6095  N N   . ALA C 1 28  ? -23.795 -65.087 -29.426 1.00 43.51  ? 28  ALA C N   1 
ATOM 6096  C CA  . ALA C 1 28  ? -22.764 -65.343 -30.425 1.00 44.82  ? 28  ALA C CA  1 
ATOM 6097  C C   . ALA C 1 28  ? -22.397 -66.820 -30.467 1.00 45.17  ? 28  ALA C C   1 
ATOM 6098  O O   . ALA C 1 28  ? -22.318 -67.424 -31.542 1.00 45.04  ? 28  ALA C O   1 
ATOM 6099  C CB  . ALA C 1 28  ? -21.528 -64.490 -30.130 1.00 44.43  ? 28  ALA C CB  1 
ATOM 6100  N N   . LYS C 1 29  ? -22.168 -67.416 -29.297 1.00 54.36  ? 29  LYS C N   1 
ATOM 6101  C CA  . LYS C 1 29  ? -21.855 -68.842 -29.242 1.00 52.45  ? 29  LYS C CA  1 
ATOM 6102  C C   . LYS C 1 29  ? -22.999 -69.686 -29.792 1.00 48.49  ? 29  LYS C C   1 
ATOM 6103  O O   . LYS C 1 29  ? -22.769 -70.728 -30.414 1.00 52.97  ? 29  LYS C O   1 
ATOM 6104  C CB  . LYS C 1 29  ? -21.540 -69.259 -27.805 1.00 49.45  ? 29  LYS C CB  1 
ATOM 6105  C CG  . LYS C 1 29  ? -20.384 -68.508 -27.181 1.00 47.32  ? 29  LYS C CG  1 
ATOM 6106  C CD  . LYS C 1 29  ? -20.283 -68.814 -25.699 1.00 60.20  ? 29  LYS C CD  1 
ATOM 6107  C CE  . LYS C 1 29  ? -19.939 -70.275 -25.453 1.00 65.97  ? 29  LYS C CE  1 
ATOM 6108  N NZ  . LYS C 1 29  ? -19.751 -70.557 -24.005 1.00 59.10  ? 29  LYS C NZ  1 
ATOM 6109  N N   . GLN C 1 30  ? -24.243 -69.251 -29.570 1.00 49.29  ? 30  GLN C N   1 
ATOM 6110  C CA  . GLN C 1 30  ? -25.382 -70.028 -30.050 1.00 51.11  ? 30  GLN C CA  1 
ATOM 6111  C C   . GLN C 1 30  ? -25.547 -69.906 -31.561 1.00 48.71  ? 30  GLN C C   1 
ATOM 6112  O O   . GLN C 1 30  ? -25.907 -70.880 -32.232 1.00 49.42  ? 30  GLN C O   1 
ATOM 6113  C CB  . GLN C 1 30  ? -26.657 -69.591 -29.333 1.00 46.00  ? 30  GLN C CB  1 
ATOM 6114  C CG  . GLN C 1 30  ? -26.690 -69.974 -27.867 1.00 54.84  ? 30  GLN C CG  1 
ATOM 6115  C CD  . GLN C 1 30  ? -26.523 -71.467 -27.652 1.00 57.22  ? 30  GLN C CD  1 
ATOM 6116  O OE1 . GLN C 1 30  ? -27.124 -72.279 -28.359 1.00 63.70  ? 30  GLN C OE1 1 
ATOM 6117  N NE2 . GLN C 1 30  ? -25.697 -71.836 -26.679 1.00 55.94  ? 30  GLN C NE2 1 
ATOM 6118  N N   . LEU C 1 31  ? -25.297 -68.723 -32.117 1.00 49.30  ? 31  LEU C N   1 
ATOM 6119  C CA  . LEU C 1 31  ? -25.436 -68.558 -33.556 1.00 53.89  ? 31  LEU C CA  1 
ATOM 6120  C C   . LEU C 1 31  ? -24.220 -69.055 -34.321 1.00 57.31  ? 31  LEU C C   1 
ATOM 6121  O O   . LEU C 1 31  ? -24.306 -69.244 -35.539 1.00 51.77  ? 31  LEU C O   1 
ATOM 6122  C CB  . LEU C 1 31  ? -25.697 -67.091 -33.903 1.00 49.45  ? 31  LEU C CB  1 
ATOM 6123  C CG  . LEU C 1 31  ? -26.864 -66.369 -33.222 1.00 48.91  ? 31  LEU C CG  1 
ATOM 6124  C CD1 . LEU C 1 31  ? -27.098 -65.013 -33.859 1.00 42.26  ? 31  LEU C CD1 1 
ATOM 6125  C CD2 . LEU C 1 31  ? -28.129 -67.200 -33.253 1.00 61.16  ? 31  LEU C CD2 1 
ATOM 6126  N N   . ALA C 1 32  ? -23.090 -69.270 -33.641 1.00 60.86  ? 32  ALA C N   1 
ATOM 6127  C CA  . ALA C 1 32  ? -21.901 -69.789 -34.306 1.00 50.40  ? 32  ALA C CA  1 
ATOM 6128  C C   . ALA C 1 32  ? -21.925 -71.303 -34.462 1.00 61.20  ? 32  ALA C C   1 
ATOM 6129  O O   . ALA C 1 32  ? -21.232 -71.832 -35.338 1.00 71.64  ? 32  ALA C O   1 
ATOM 6130  C CB  . ALA C 1 32  ? -20.646 -69.372 -33.537 1.00 45.51  ? 32  ALA C CB  1 
ATOM 6131  N N   . LYS C 1 33  ? -22.703 -72.008 -33.646 1.00 61.24  ? 33  LYS C N   1 
ATOM 6132  C CA  . LYS C 1 33  ? -22.783 -73.459 -33.727 1.00 60.94  ? 33  LYS C CA  1 
ATOM 6133  C C   . LYS C 1 33  ? -23.858 -73.948 -34.685 1.00 64.15  ? 33  LYS C C   1 
ATOM 6134  O O   . LYS C 1 33  ? -23.950 -75.158 -34.921 1.00 64.30  ? 33  LYS C O   1 
ATOM 6135  C CB  . LYS C 1 33  ? -23.028 -74.048 -32.335 1.00 57.45  ? 33  LYS C CB  1 
ATOM 6136  C CG  . LYS C 1 33  ? -24.223 -73.451 -31.626 1.00 62.02  ? 33  LYS C CG  1 
ATOM 6137  C CD  . LYS C 1 33  ? -24.267 -73.856 -30.166 1.00 61.30  ? 33  LYS C CD  1 
ATOM 6138  C CE  . LYS C 1 33  ? -24.574 -75.332 -30.008 1.00 70.50  ? 33  LYS C CE  1 
ATOM 6139  N NZ  . LYS C 1 33  ? -24.730 -75.697 -28.573 1.00 67.11  ? 33  LYS C NZ  1 
ATOM 6140  N N   . ARG C 1 34  ? -24.648 -72.990 -35.186 1.00 64.40  ? 34  ARG C N   1 
ATOM 6141  C CA  . ARG C 1 34  ? -25.745 -73.292 -36.137 1.00 65.81  ? 34  ARG C CA  1 
ATOM 6142  C C   . ARG C 1 34  ? -25.570 -72.430 -37.383 1.00 79.08  ? 34  ARG C C   1 
ATOM 6143  O O   . ARG C 1 34  ? -25.309 -71.234 -37.234 1.00 80.62  ? 34  ARG C O   1 
ATOM 6144  C CB  . ARG C 1 34  ? -27.115 -73.027 -35.516 1.00 67.73  ? 34  ARG C CB  1 
ATOM 6145  C CG  . ARG C 1 34  ? -27.274 -71.695 -34.807 1.00 75.31  ? 34  ARG C CG  1 
ATOM 6146  C CD  . ARG C 1 34  ? -28.580 -71.755 -34.047 1.00 68.03  ? 34  ARG C CD  1 
ATOM 6147  N NE  . ARG C 1 34  ? -28.776 -73.070 -33.462 1.00 61.43  ? 34  ARG C NE  1 
ATOM 6148  C CZ  . ARG C 1 34  ? -28.603 -73.364 -32.182 1.00 65.42  ? 34  ARG C CZ  1 
ATOM 6149  N NH1 . ARG C 1 34  ? -28.242 -72.427 -31.325 1.00 61.35  ? 34  ARG C NH1 1 
ATOM 6150  N NH2 . ARG C 1 34  ? -28.802 -74.597 -31.764 1.00 78.53  ? 34  ARG C NH2 1 
ATOM 6151  N N   . ASN C 1 35  ? -25.590 -73.049 -38.560 1.00 88.67  ? 35  ASN C N   1 
ATOM 6152  C CA  . ASN C 1 35  ? -25.459 -72.325 -39.854 1.00 89.45  ? 35  ASN C CA  1 
ATOM 6153  C C   . ASN C 1 35  ? -24.037 -71.799 -39.971 1.00 94.32  ? 35  ASN C C   1 
ATOM 6154  O O   . ASN C 1 35  ? -23.781 -71.032 -40.908 1.00 87.24  ? 35  ASN C O   1 
ATOM 6155  C CB  . ASN C 1 35  ? -26.581 -71.323 -40.122 1.00 87.02  ? 35  ASN C CB  1 
ATOM 6156  C CG  . ASN C 1 35  ? -27.668 -71.898 -41.007 1.00 99.02  ? 35  ASN C CG  1 
ATOM 6157  O OD1 . ASN C 1 35  ? -27.743 -73.110 -41.196 1.00 104.30 ? 35  ASN C OD1 1 
ATOM 6158  N ND2 . ASN C 1 35  ? -28.513 -71.040 -41.554 1.00 97.18  ? 35  ASN C ND2 1 
ATOM 6159  N N   . CYS C 1 36  ? -23.175 -72.163 -39.025 1.00 92.61  ? 36  CYS C N   1 
ATOM 6160  C CA  . CYS C 1 36  ? -21.743 -71.803 -39.135 1.00 101.46 ? 36  CYS C CA  1 
ATOM 6161  C C   . CYS C 1 36  ? -21.673 -70.312 -39.427 1.00 95.33  ? 36  CYS C C   1 
ATOM 6162  O O   . CYS C 1 36  ? -20.857 -69.912 -40.274 1.00 98.68  ? 36  CYS C O   1 
ATOM 6163  C CB  . CYS C 1 36  ? -21.059 -72.622 -40.221 1.00 99.34  ? 36  CYS C CB  1 
ATOM 6164  S SG  . CYS C 1 36  ? -21.160 -74.407 -39.933 1.00 116.67 ? 36  CYS C SG  1 
ATOM 6165  N N   . ASN C 1 37  ? -22.585 -69.555 -38.831 1.00 77.54  ? 37  ASN C N   1 
ATOM 6166  C CA  . ASN C 1 37  ? -22.622 -68.095 -39.062 1.00 66.74  ? 37  ASN C CA  1 
ATOM 6167  C C   . ASN C 1 37  ? -21.253 -67.526 -38.725 1.00 65.62  ? 37  ASN C C   1 
ATOM 6168  O O   . ASN C 1 37  ? -20.782 -67.770 -37.609 1.00 64.24  ? 37  ASN C O   1 
ATOM 6169  C CB  . ASN C 1 37  ? -23.752 -67.431 -38.272 1.00 63.47  ? 37  ASN C CB  1 
ATOM 6170  C CG  . ASN C 1 37  ? -25.130 -67.923 -38.650 1.00 67.83  ? 37  ASN C CG  1 
ATOM 6171  O OD1 . ASN C 1 37  ? -25.339 -68.399 -39.761 1.00 81.11  ? 37  ASN C OD1 1 
ATOM 6172  N ND2 . ASN C 1 37  ? -26.078 -67.798 -37.739 1.00 62.38  ? 37  ASN C ND2 1 
ATOM 6173  N N   . VAL C 1 38  ? -20.614 -66.853 -39.689 1.00 59.81  ? 38  VAL C N   1 
ATOM 6174  C CA  . VAL C 1 38  ? -19.315 -66.173 -39.406 1.00 63.44  ? 38  VAL C CA  1 
ATOM 6175  C C   . VAL C 1 38  ? -19.631 -65.113 -38.354 1.00 62.78  ? 38  VAL C C   1 
ATOM 6176  O O   . VAL C 1 38  ? -20.523 -64.283 -38.611 1.00 56.56  ? 38  VAL C O   1 
ATOM 6177  C CB  . VAL C 1 38  ? -18.719 -65.545 -40.679 1.00 67.50  ? 38  VAL C CB  1 
ATOM 6178  C CG1 . VAL C 1 38  ? -17.384 -64.867 -40.408 1.00 57.32  ? 38  VAL C CG1 1 
ATOM 6179  C CG2 . VAL C 1 38  ? -18.586 -66.566 -41.799 1.00 65.18  ? 38  VAL C CG2 1 
ATOM 6180  N N   . PHE C 1 39  ? -18.910 -65.094 -37.240 1.00 58.33  ? 39  PHE C N   1 
ATOM 6181  C CA  . PHE C 1 39  ? -19.340 -64.179 -36.163 1.00 50.15  ? 39  PHE C CA  1 
ATOM 6182  C C   . PHE C 1 39  ? -18.299 -63.131 -35.822 1.00 48.96  ? 39  PHE C C   1 
ATOM 6183  O O   . PHE C 1 39  ? -17.176 -63.504 -35.556 1.00 44.06  ? 39  PHE C O   1 
ATOM 6184  C CB  . PHE C 1 39  ? -19.780 -64.993 -34.957 1.00 56.26  ? 39  PHE C CB  1 
ATOM 6185  C CG  . PHE C 1 39  ? -20.979 -65.807 -35.316 1.00 53.07  ? 39  PHE C CG  1 
ATOM 6186  C CD1 . PHE C 1 39  ? -22.236 -65.240 -35.274 1.00 54.75  ? 39  PHE C CD1 1 
ATOM 6187  C CD2 . PHE C 1 39  ? -20.853 -67.157 -35.564 1.00 56.86  ? 39  PHE C CD2 1 
ATOM 6188  C CE1 . PHE C 1 39  ? -23.351 -66.007 -35.544 1.00 62.99  ? 39  PHE C CE1 1 
ATOM 6189  C CE2 . PHE C 1 39  ? -21.969 -67.915 -35.852 1.00 67.54  ? 39  PHE C CE2 1 
ATOM 6190  C CZ  . PHE C 1 39  ? -23.213 -67.341 -35.837 1.00 67.38  ? 39  PHE C CZ  1 
ATOM 6191  N N   . LEU C 1 40  ? -18.714 -61.866 -35.820 1.00 44.74  ? 40  LEU C N   1 
ATOM 6192  C CA  . LEU C 1 40  ? -17.795 -60.751 -35.479 1.00 43.92  ? 40  LEU C CA  1 
ATOM 6193  C C   . LEU C 1 40  ? -18.412 -60.003 -34.293 1.00 40.33  ? 40  LEU C C   1 
ATOM 6194  O O   . LEU C 1 40  ? -19.618 -59.725 -34.352 1.00 47.51  ? 40  LEU C O   1 
ATOM 6195  C CB  . LEU C 1 40  ? -17.687 -59.836 -36.703 1.00 45.55  ? 40  LEU C CB  1 
ATOM 6196  C CG  . LEU C 1 40  ? -17.503 -60.552 -38.040 1.00 52.43  ? 40  LEU C CG  1 
ATOM 6197  C CD1 . LEU C 1 40  ? -18.074 -59.732 -39.188 1.00 58.23  ? 40  LEU C CD1 1 
ATOM 6198  C CD2 . LEU C 1 40  ? -16.039 -60.887 -38.287 1.00 54.09  ? 40  LEU C CD2 1 
ATOM 6199  N N   . CYS C 1 41  ? -17.737 -59.879 -33.142 1.00 44.15  ? 41  CYS C N   1 
ATOM 6200  C CA  . CYS C 1 41  ? -18.312 -59.231 -31.913 1.00 37.20  ? 41  CYS C CA  1 
ATOM 6201  C C   . CYS C 1 41  ? -17.471 -58.007 -31.565 1.00 52.22  ? 41  CYS C C   1 
ATOM 6202  O O   . CYS C 1 41  ? -16.275 -58.183 -31.395 1.00 53.39  ? 41  CYS C O   1 
ATOM 6203  C CB  . CYS C 1 41  ? -18.337 -60.184 -30.729 1.00 42.17  ? 41  CYS C CB  1 
ATOM 6204  S SG  . CYS C 1 41  ? -19.284 -59.607 -29.298 1.00 67.27  ? 41  CYS C SG  1 
ATOM 6205  N N   . SER C 1 42  ? -18.050 -56.806 -31.683 1.00 46.75  ? 42  SER C N   1 
ATOM 6206  C CA  . SER C 1 42  ? -17.264 -55.555 -31.502 1.00 48.29  ? 42  SER C CA  1 
ATOM 6207  C C   . SER C 1 42  ? -17.269 -55.122 -30.038 1.00 50.11  ? 42  SER C C   1 
ATOM 6208  O O   . SER C 1 42  ? -18.308 -54.609 -29.573 1.00 50.68  ? 42  SER C O   1 
ATOM 6209  C CB  . SER C 1 42  ? -17.770 -54.461 -32.402 1.00 52.26  ? 42  SER C CB  1 
ATOM 6210  O OG  . SER C 1 42  ? -16.927 -53.321 -32.334 1.00 59.67  ? 42  SER C OG  1 
ATOM 6211  N N   . THR C 1 43  ? -16.143 -55.315 -29.352 1.00 60.86  ? 43  THR C N   1 
ATOM 6212  C CA  . THR C 1 43  ? -16.040 -54.947 -27.919 1.00 65.66  ? 43  THR C CA  1 
ATOM 6213  C C   . THR C 1 43  ? -14.698 -54.255 -27.686 1.00 71.58  ? 43  THR C C   1 
ATOM 6214  O O   . THR C 1 43  ? -13.752 -54.547 -28.442 1.00 70.98  ? 43  THR C O   1 
ATOM 6215  C CB  . THR C 1 43  ? -16.145 -56.207 -27.051 1.00 69.33  ? 43  THR C CB  1 
ATOM 6216  O OG1 . THR C 1 43  ? -15.410 -57.224 -27.732 1.00 63.30  ? 43  THR C OG1 1 
ATOM 6217  C CG2 . THR C 1 43  ? -17.568 -56.680 -26.860 1.00 60.73  ? 43  THR C CG2 1 
ATOM 6218  N N   . PRO C 1 44  ? -14.557 -53.264 -26.760 1.00 68.60  ? 44  PRO C N   1 
ATOM 6219  C CA  . PRO C 1 44  ? -13.243 -52.700 -26.409 1.00 63.45  ? 44  PRO C CA  1 
ATOM 6220  C C   . PRO C 1 44  ? -12.356 -53.827 -25.867 1.00 69.62  ? 44  PRO C C   1 
ATOM 6221  O O   . PRO C 1 44  ? -12.904 -54.725 -25.278 1.00 66.86  ? 44  PRO C O   1 
ATOM 6222  C CB  . PRO C 1 44  ? -13.541 -51.624 -25.366 1.00 61.36  ? 44  PRO C CB  1 
ATOM 6223  C CG  . PRO C 1 44  ? -14.937 -51.202 -25.693 1.00 70.99  ? 44  PRO C CG  1 
ATOM 6224  C CD  . PRO C 1 44  ? -15.613 -52.506 -26.062 1.00 79.49  ? 44  PRO C CD  1 
ATOM 6225  N N   . ILE C 1 45  ? -11.034 -53.758 -26.039 1.00 67.24  ? 45  ILE C N   1 
ATOM 6226  C CA  . ILE C 1 45  ? -10.114 -54.888 -25.710 1.00 58.93  ? 45  ILE C CA  1 
ATOM 6227  C C   . ILE C 1 45  ? -10.298 -55.288 -24.239 1.00 54.53  ? 45  ILE C C   1 
ATOM 6228  O O   . ILE C 1 45  ? -10.315 -56.502 -23.965 1.00 57.49  ? 45  ILE C O   1 
ATOM 6229  C CB  . ILE C 1 45  ? -8.655  -54.528 -26.064 1.00 57.75  ? 45  ILE C CB  1 
ATOM 6230  C CG1 . ILE C 1 45  ? -7.675  -55.650 -25.706 1.00 66.76  ? 45  ILE C CG1 1 
ATOM 6231  C CG2 . ILE C 1 45  ? -8.246  -53.196 -25.446 1.00 77.48  ? 45  ILE C CG2 1 
ATOM 6232  C CD1 . ILE C 1 45  ? -7.863  -56.910 -26.519 1.00 47.54  ? 45  ILE C CD1 1 
ATOM 6233  N N   . ASN C 1 46  ? -10.472 -54.315 -23.341 1.00 52.81  ? 46  ASN C N   1 
ATOM 6234  C CA  . ASN C 1 46  ? -10.690 -54.625 -21.903 1.00 65.21  ? 46  ASN C CA  1 
ATOM 6235  C C   . ASN C 1 46  ? -11.990 -55.426 -21.733 1.00 64.68  ? 46  ASN C C   1 
ATOM 6236  O O   . ASN C 1 46  ? -11.986 -56.393 -20.952 1.00 61.33  ? 46  ASN C O   1 
ATOM 6237  C CB  . ASN C 1 46  ? -10.721 -53.351 -21.056 1.00 60.29  ? 46  ASN C CB  1 
ATOM 6238  C CG  . ASN C 1 46  ? -10.737 -53.622 -19.566 1.00 72.75  ? 46  ASN C CG  1 
ATOM 6239  O OD1 . ASN C 1 46  ? -10.193 -54.623 -19.105 1.00 83.36  ? 46  ASN C OD1 1 
ATOM 6240  N ND2 . ASN C 1 46  ? -11.348 -52.730 -18.805 1.00 75.98  ? 46  ASN C ND2 1 
ATOM 6241  N N   . LEU C 1 47  ? -13.062 -55.027 -22.422 1.00 69.77  ? 47  LEU C N   1 
ATOM 6242  C CA  . LEU C 1 47  ? -14.355 -55.764 -22.336 1.00 59.47  ? 47  LEU C CA  1 
ATOM 6243  C C   . LEU C 1 47  ? -14.240 -57.162 -22.956 1.00 55.14  ? 47  LEU C C   1 
ATOM 6244  O O   . LEU C 1 47  ? -14.829 -58.098 -22.395 1.00 61.71  ? 47  LEU C O   1 
ATOM 6245  C CB  . LEU C 1 47  ? -15.474 -54.939 -22.979 1.00 54.84  ? 47  LEU C CB  1 
ATOM 6246  C CG  . LEU C 1 47  ? -16.410 -54.246 -21.989 1.00 63.75  ? 47  LEU C CG  1 
ATOM 6247  C CD1 . LEU C 1 47  ? -15.647 -53.289 -21.088 1.00 59.58  ? 47  LEU C CD1 1 
ATOM 6248  C CD2 . LEU C 1 47  ? -17.519 -53.513 -22.720 1.00 71.57  ? 47  LEU C CD2 1 
ATOM 6249  N N   . SER C 1 48  ? -13.535 -57.292 -24.084 1.00 60.71  ? 48  SER C N   1 
ATOM 6250  C CA  . SER C 1 48  ? -13.429 -58.603 -24.778 1.00 67.64  ? 48  SER C CA  1 
ATOM 6251  C C   . SER C 1 48  ? -12.517 -59.531 -23.971 1.00 70.80  ? 48  SER C C   1 
ATOM 6252  O O   . SER C 1 48  ? -12.714 -60.757 -24.036 1.00 74.22  ? 48  SER C O   1 
ATOM 6253  C CB  . SER C 1 48  ? -12.906 -58.423 -26.179 1.00 58.32  ? 48  SER C CB  1 
ATOM 6254  O OG  . SER C 1 48  ? -11.575 -57.934 -26.164 1.00 67.31  ? 48  SER C OG  1 
ATOM 6255  N N   . SER C 1 49  ? -11.563 -58.958 -23.238 1.00 68.17  ? 49  SER C N   1 
ATOM 6256  C CA  . SER C 1 49  ? -10.588 -59.754 -22.441 1.00 65.94  ? 49  SER C CA  1 
ATOM 6257  C C   . SER C 1 49  ? -11.279 -60.771 -21.544 1.00 67.03  ? 49  SER C C   1 
ATOM 6258  O O   . SER C 1 49  ? -10.761 -61.883 -21.424 1.00 73.90  ? 49  SER C O   1 
ATOM 6259  C CB  . SER C 1 49  ? -9.758  -58.846 -21.594 1.00 69.57  ? 49  SER C CB  1 
ATOM 6260  O OG  . SER C 1 49  ? -10.464 -58.472 -20.424 1.00 72.63  ? 49  SER C OG  1 
ATOM 6261  N N   . ILE C 1 50  ? -12.379 -60.381 -20.904 1.00 63.41  ? 50  ILE C N   1 
ATOM 6262  C CA  . ILE C 1 50  ? -13.124 -61.275 -19.966 1.00 75.69  ? 50  ILE C CA  1 
ATOM 6263  C C   . ILE C 1 50  ? -13.749 -62.444 -20.717 1.00 77.39  ? 50  ILE C C   1 
ATOM 6264  O O   . ILE C 1 50  ? -13.841 -63.521 -20.126 1.00 87.72  ? 50  ILE C O   1 
ATOM 6265  C CB  . ILE C 1 50  ? -14.208 -60.494 -19.217 1.00 84.55  ? 50  ILE C CB  1 
ATOM 6266  C CG1 . ILE C 1 50  ? -14.655 -61.262 -17.972 1.00 91.59  ? 50  ILE C CG1 1 
ATOM 6267  C CG2 . ILE C 1 50  ? -15.378 -60.159 -20.124 1.00 81.13  ? 50  ILE C CG2 1 
ATOM 6268  C CD1 . ILE C 1 50  ? -13.506 -61.847 -17.178 1.00 96.95  ? 50  ILE C CD1 1 
ATOM 6269  N N   . LYS C 1 51  ? -14.153 -62.232 -21.961 1.00 70.32  ? 51  LYS C N   1 
ATOM 6270  C CA  . LYS C 1 51  ? -14.862 -63.284 -22.716 1.00 67.95  ? 51  LYS C CA  1 
ATOM 6271  C C   . LYS C 1 51  ? -13.866 -64.239 -23.357 1.00 66.95  ? 51  LYS C C   1 
ATOM 6272  O O   . LYS C 1 51  ? -14.314 -65.169 -24.022 1.00 77.07  ? 51  LYS C O   1 
ATOM 6273  C CB  . LYS C 1 51  ? -15.756 -62.629 -23.766 1.00 61.47  ? 51  LYS C CB  1 
ATOM 6274  C CG  . LYS C 1 51  ? -16.997 -61.985 -23.173 1.00 65.09  ? 51  LYS C CG  1 
ATOM 6275  C CD  . LYS C 1 51  ? -17.627 -62.864 -22.110 1.00 75.82  ? 51  LYS C CD  1 
ATOM 6276  C CE  . LYS C 1 51  ? -18.757 -62.200 -21.353 1.00 75.10  ? 51  LYS C CE  1 
ATOM 6277  N NZ  . LYS C 1 51  ? -19.313 -63.103 -20.321 1.00 55.36  ? 51  LYS C NZ  1 
ATOM 6278  N N   . ASP C 1 52  ? -12.570 -64.020 -23.178 1.00 70.78  ? 52  ASP C N   1 
ATOM 6279  C CA  . ASP C 1 52  ? -11.612 -64.906 -23.895 1.00 84.18  ? 52  ASP C CA  1 
ATOM 6280  C C   . ASP C 1 52  ? -11.420 -66.179 -23.062 1.00 86.08  ? 52  ASP C C   1 
ATOM 6281  O O   . ASP C 1 52  ? -10.625 -66.167 -22.104 1.00 74.09  ? 52  ASP C O   1 
ATOM 6282  C CB  . ASP C 1 52  ? -10.328 -64.173 -24.289 1.00 75.15  ? 52  ASP C CB  1 
ATOM 6283  C CG  . ASP C 1 52  ? -9.549  -64.863 -25.387 1.00 79.06  ? 52  ASP C CG  1 
ATOM 6284  O OD1 . ASP C 1 52  ? -9.188  -66.033 -25.188 1.00 95.35  ? 52  ASP C OD1 1 
ATOM 6285  O OD2 . ASP C 1 52  ? -9.305  -64.219 -26.417 1.00 77.65  ? 52  ASP C OD2 1 
ATOM 6286  N N   . LYS C 1 53  ? -12.161 -67.231 -23.394 1.00 83.28  ? 53  LYS C N   1 
ATOM 6287  C CA  . LYS C 1 53  ? -12.087 -68.478 -22.600 1.00 88.06  ? 53  LYS C CA  1 
ATOM 6288  C C   . LYS C 1 53  ? -12.617 -69.611 -23.482 1.00 91.86  ? 53  LYS C C   1 
ATOM 6289  O O   . LYS C 1 53  ? -11.820 -70.494 -23.810 1.00 94.85  ? 53  LYS C O   1 
ATOM 6290  C CB  . LYS C 1 53  ? -12.816 -68.251 -21.275 1.00 88.43  ? 53  LYS C CB  1 
ATOM 6291  C CG  . LYS C 1 53  ? -14.195 -67.617 -21.406 1.00 75.05  ? 53  LYS C CG  1 
ATOM 6292  C CD  . LYS C 1 53  ? -15.106 -67.896 -20.236 1.00 74.32  ? 53  LYS C CD  1 
ATOM 6293  C CE  . LYS C 1 53  ? -16.533 -67.447 -20.473 1.00 84.24  ? 53  LYS C CE  1 
ATOM 6294  N NZ  . LYS C 1 53  ? -16.658 -65.972 -20.467 1.00 68.76  ? 53  LYS C NZ  1 
ATOM 6295  N N   . ASP C 1 54  ? -13.904 -69.596 -23.861 1.00 90.21  ? 54  ASP C N   1 
ATOM 6296  C CA  . ASP C 1 54  ? -14.351 -70.620 -24.842 1.00 90.66  ? 54  ASP C CA  1 
ATOM 6297  C C   . ASP C 1 54  ? -15.079 -69.902 -25.981 1.00 83.94  ? 54  ASP C C   1 
ATOM 6298  O O   . ASP C 1 54  ? -16.318 -70.021 -26.055 1.00 79.39  ? 54  ASP C O   1 
ATOM 6299  C CB  . ASP C 1 54  ? -15.240 -71.677 -24.185 1.00 97.42  ? 54  ASP C CB  1 
ATOM 6300  C CG  . ASP C 1 54  ? -14.526 -72.521 -23.144 1.00 107.93 ? 54  ASP C CG  1 
ATOM 6301  O OD1 . ASP C 1 54  ? -13.316 -72.297 -22.936 1.00 107.68 ? 54  ASP C OD1 1 
ATOM 6302  O OD2 . ASP C 1 54  ? -15.186 -73.394 -22.547 1.00 111.19 ? 54  ASP C OD2 1 
ATOM 6303  N N   . SER C 1 55  ? -14.337 -69.178 -26.825 1.00 86.52  ? 55  SER C N   1 
ATOM 6304  C CA  . SER C 1 55  ? -14.980 -68.387 -27.908 1.00 77.92  ? 55  SER C CA  1 
ATOM 6305  C C   . SER C 1 55  ? -14.297 -68.658 -29.252 1.00 76.48  ? 55  SER C C   1 
ATOM 6306  O O   . SER C 1 55  ? -14.531 -67.876 -30.193 1.00 77.44  ? 55  SER C O   1 
ATOM 6307  C CB  . SER C 1 55  ? -14.956 -66.917 -27.577 1.00 76.18  ? 55  SER C CB  1 
ATOM 6308  O OG  . SER C 1 55  ? -13.623 -66.460 -27.400 1.00 82.80  ? 55  SER C OG  1 
ATOM 6309  N N   . SER C 1 56  ? -13.490 -69.723 -29.345 1.00 79.43  ? 56  SER C N   1 
ATOM 6310  C CA  . SER C 1 56  ? -12.880 -70.050 -30.628 1.00 77.27  ? 56  SER C CA  1 
ATOM 6311  C C   . SER C 1 56  ? -13.887 -70.035 -31.772 1.00 76.76  ? 56  SER C C   1 
ATOM 6312  O O   . SER C 1 56  ? -13.491 -69.866 -32.930 1.00 80.70  ? 56  SER C O   1 
ATOM 6313  C CB  . SER C 1 56  ? -12.189 -71.410 -30.543 1.00 86.13  ? 56  SER C CB  1 
ATOM 6314  O OG  . SER C 1 56  ? -11.123 -71.382 -29.610 1.00 97.61  ? 56  SER C OG  1 
ATOM 6315  N N   . ALA C 1 57  ? -15.179 -70.191 -31.473 1.00 74.64  ? 57  ALA C N   1 
ATOM 6316  C CA  . ALA C 1 57  ? -16.199 -70.162 -32.514 1.00 64.15  ? 57  ALA C CA  1 
ATOM 6317  C C   . ALA C 1 57  ? -16.462 -68.746 -33.007 1.00 68.49  ? 57  ALA C C   1 
ATOM 6318  O O   . ALA C 1 57  ? -16.605 -68.522 -34.212 1.00 80.19  ? 57  ALA C O   1 
ATOM 6319  C CB  . ALA C 1 57  ? -17.492 -70.800 -32.005 1.00 50.75  ? 57  ALA C CB  1 
ATOM 6320  N N   . SER C 1 58  ? -16.527 -67.782 -32.094 1.00 66.96  ? 58  SER C N   1 
ATOM 6321  C CA  . SER C 1 58  ? -16.744 -66.391 -32.449 1.00 57.11  ? 58  SER C CA  1 
ATOM 6322  C C   . SER C 1 58  ? -15.415 -65.695 -32.725 1.00 58.95  ? 58  SER C C   1 
ATOM 6323  O O   . SER C 1 58  ? -14.343 -66.171 -32.347 1.00 63.05  ? 58  SER C O   1 
ATOM 6324  C CB  . SER C 1 58  ? -17.490 -65.658 -31.333 1.00 51.04  ? 58  SER C CB  1 
ATOM 6325  O OG  . SER C 1 58  ? -18.701 -66.318 -30.997 1.00 61.52  ? 58  SER C OG  1 
ATOM 6326  N N   . ILE C 1 59  ? -15.502 -64.549 -33.393 1.00 63.74  ? 59  ILE C N   1 
ATOM 6327  C CA  . ILE C 1 59  ? -14.347 -63.706 -33.678 1.00 54.57  ? 59  ILE C CA  1 
ATOM 6328  C C   . ILE C 1 59  ? -14.570 -62.366 -32.989 1.00 49.45  ? 59  ILE C C   1 
ATOM 6329  O O   . ILE C 1 59  ? -15.584 -61.700 -33.227 1.00 59.28  ? 59  ILE C O   1 
ATOM 6330  C CB  . ILE C 1 59  ? -14.128 -63.522 -35.188 1.00 53.42  ? 59  ILE C CB  1 
ATOM 6331  C CG1 . ILE C 1 59  ? -13.713 -64.849 -35.835 1.00 56.63  ? 59  ILE C CG1 1 
ATOM 6332  C CG2 . ILE C 1 59  ? -13.087 -62.444 -35.453 1.00 54.03  ? 59  ILE C CG2 1 
ATOM 6333  C CD1 . ILE C 1 59  ? -13.469 -64.756 -37.327 1.00 59.02  ? 59  ILE C CD1 1 
ATOM 6334  N N   . LYS C 1 60  ? -13.641 -62.055 -32.102 1.00 41.97  ? 60  LYS C N   1 
ATOM 6335  C CA  . LYS C 1 60  ? -13.782 -60.820 -31.318 1.00 52.84  ? 60  LYS C CA  1 
ATOM 6336  C C   . LYS C 1 60  ? -13.006 -59.732 -32.045 1.00 50.62  ? 60  LYS C C   1 
ATOM 6337  O O   . LYS C 1 60  ? -11.927 -60.014 -32.551 1.00 48.38  ? 60  LYS C O   1 
ATOM 6338  C CB  . LYS C 1 60  ? -13.382 -61.123 -29.874 1.00 52.22  ? 60  LYS C CB  1 
ATOM 6339  C CG  . LYS C 1 60  ? -14.086 -62.322 -29.263 1.00 61.63  ? 60  LYS C CG  1 
ATOM 6340  C CD  . LYS C 1 60  ? -13.177 -63.126 -28.375 1.00 64.84  ? 60  LYS C CD  1 
ATOM 6341  C CE  . LYS C 1 60  ? -12.587 -62.293 -27.261 1.00 74.51  ? 60  LYS C CE  1 
ATOM 6342  N NZ  . LYS C 1 60  ? -13.644 -61.665 -26.435 1.00 80.71  ? 60  LYS C NZ  1 
ATOM 6343  N N   . LEU C 1 61  ? -13.575 -58.543 -32.095 1.00 52.29  ? 61  LEU C N   1 
ATOM 6344  C CA  . LEU C 1 61  ? -12.980 -57.432 -32.860 1.00 49.76  ? 61  LEU C CA  1 
ATOM 6345  C C   . LEU C 1 61  ? -12.787 -56.263 -31.904 1.00 50.76  ? 61  LEU C C   1 
ATOM 6346  O O   . LEU C 1 61  ? -13.697 -55.972 -31.149 1.00 55.96  ? 61  LEU C O   1 
ATOM 6347  C CB  . LEU C 1 61  ? -13.968 -57.109 -33.978 1.00 53.00  ? 61  LEU C CB  1 
ATOM 6348  C CG  . LEU C 1 61  ? -13.825 -55.738 -34.613 1.00 55.96  ? 61  LEU C CG  1 
ATOM 6349  C CD1 . LEU C 1 61  ? -12.786 -55.769 -35.719 1.00 67.49  ? 61  LEU C CD1 1 
ATOM 6350  C CD2 . LEU C 1 61  ? -15.169 -55.311 -35.152 1.00 63.63  ? 61  LEU C CD2 1 
ATOM 6351  N N   . VAL C 1 62  ? -11.633 -55.625 -31.943 1.00 47.36  ? 62  VAL C N   1 
ATOM 6352  C CA  . VAL C 1 62  ? -11.353 -54.573 -30.938 1.00 53.00  ? 62  VAL C CA  1 
ATOM 6353  C C   . VAL C 1 62  ? -12.013 -53.258 -31.325 1.00 50.95  ? 62  VAL C C   1 
ATOM 6354  O O   . VAL C 1 62  ? -12.541 -53.159 -32.424 1.00 61.46  ? 62  VAL C O   1 
ATOM 6355  C CB  . VAL C 1 62  ? -9.837  -54.395 -30.770 1.00 60.47  ? 62  VAL C CB  1 
ATOM 6356  C CG1 . VAL C 1 62  ? -9.175  -55.651 -30.232 1.00 58.46  ? 62  VAL C CG1 1 
ATOM 6357  C CG2 . VAL C 1 62  ? -9.173  -53.953 -32.062 1.00 79.95  ? 62  VAL C CG2 1 
ATOM 6358  N N   . GLU C 1 63  ? -11.911 -52.275 -30.433 1.00 68.86  ? 63  GLU C N   1 
ATOM 6359  C CA  . GLU C 1 63  ? -12.544 -50.985 -30.682 1.00 61.98  ? 63  GLU C CA  1 
ATOM 6360  C C   . GLU C 1 63  ? -11.957 -49.969 -29.716 1.00 75.11  ? 63  GLU C C   1 
ATOM 6361  O O   . GLU C 1 63  ? -12.089 -50.122 -28.499 1.00 77.41  ? 63  GLU C O   1 
ATOM 6362  C CB  . GLU C 1 63  ? -14.063 -51.061 -30.525 1.00 61.27  ? 63  GLU C CB  1 
ATOM 6363  C CG  . GLU C 1 63  ? -14.755 -49.740 -30.800 1.00 68.06  ? 63  GLU C CG  1 
ATOM 6364  C CD  . GLU C 1 63  ? -16.253 -49.884 -30.982 1.00 75.13  ? 63  GLU C CD  1 
ATOM 6365  O OE1 . GLU C 1 63  ? -16.795 -50.959 -30.654 1.00 70.53  ? 63  GLU C OE1 1 
ATOM 6366  O OE2 . GLU C 1 63  ? -16.885 -48.917 -31.462 1.00 59.02  ? 63  GLU C OE2 1 
ATOM 6367  N N   . LEU C 1 64  ? -11.313 -48.940 -30.260 1.00 70.66  ? 64  LEU C N   1 
ATOM 6368  C CA  . LEU C 1 64  ? -10.584 -47.955 -29.475 1.00 74.87  ? 64  LEU C CA  1 
ATOM 6369  C C   . LEU C 1 64  ? -11.345 -46.636 -29.453 1.00 78.28  ? 64  LEU C C   1 
ATOM 6370  O O   . LEU C 1 64  ? -11.840 -46.174 -30.486 1.00 76.60  ? 64  LEU C O   1 
ATOM 6371  C CB  . LEU C 1 64  ? -9.179  -47.734 -30.041 1.00 76.16  ? 64  LEU C CB  1 
ATOM 6372  C CG  . LEU C 1 64  ? -8.154  -48.867 -29.909 1.00 74.88  ? 64  LEU C CG  1 
ATOM 6373  C CD1 . LEU C 1 64  ? -8.165  -49.453 -28.501 1.00 70.53  ? 64  LEU C CD1 1 
ATOM 6374  C CD2 . LEU C 1 64  ? -8.346  -49.958 -30.962 1.00 50.70  ? 64  LEU C CD2 1 
ATOM 6375  N N   . HIS C 1 65  ? -11.430 -46.032 -28.272 1.00 84.03  ? 65  HIS C N   1 
ATOM 6376  C CA  . HIS C 1 65  ? -12.121 -44.758 -28.111 1.00 80.08  ? 65  HIS C CA  1 
ATOM 6377  C C   . HIS C 1 65  ? -11.118 -43.621 -27.925 1.00 84.71  ? 65  HIS C C   1 
ATOM 6378  O O   . HIS C 1 65  ? -11.321 -42.725 -27.104 1.00 82.83  ? 65  HIS C O   1 
ATOM 6379  C CB  . HIS C 1 65  ? -13.087 -44.816 -26.923 1.00 80.38  ? 65  HIS C CB  1 
ATOM 6380  C CG  . HIS C 1 65  ? -14.204 -45.795 -27.101 1.00 76.73  ? 65  HIS C CG  1 
ATOM 6381  N ND1 . HIS C 1 65  ? -14.634 -46.221 -28.339 1.00 74.49  ? 65  HIS C ND1 1 
ATOM 6382  C CD2 . HIS C 1 65  ? -14.982 -46.435 -26.193 1.00 76.84  ? 65  HIS C CD2 1 
ATOM 6383  C CE1 . HIS C 1 65  ? -15.629 -47.079 -28.189 1.00 70.12  ? 65  HIS C CE1 1 
ATOM 6384  N NE2 . HIS C 1 65  ? -15.859 -47.224 -26.898 1.00 82.22  ? 65  HIS C NE2 1 
ATOM 6385  N N   . ARG C 1 91  ? -19.367 -38.760 -19.773 1.00 111.31 ? 91  ARG C N   1 
ATOM 6386  C CA  . ARG C 1 91  ? -19.968 -38.983 -21.114 1.00 124.26 ? 91  ARG C CA  1 
ATOM 6387  C C   . ARG C 1 91  ? -19.221 -40.113 -21.818 1.00 121.54 ? 91  ARG C C   1 
ATOM 6388  O O   . ARG C 1 91  ? -18.076 -39.878 -22.223 1.00 116.59 ? 91  ARG C O   1 
ATOM 6389  C CB  . ARG C 1 91  ? -19.874 -37.708 -21.954 1.00 126.49 ? 91  ARG C CB  1 
ATOM 6390  C CG  . ARG C 1 91  ? -20.681 -36.540 -21.399 1.00 127.90 ? 91  ARG C CG  1 
ATOM 6391  C CD  . ARG C 1 91  ? -22.024 -36.404 -22.089 1.00 131.73 ? 91  ARG C CD  1 
ATOM 6392  N NE  . ARG C 1 91  ? -21.959 -36.844 -23.475 1.00 130.20 ? 91  ARG C NE  1 
ATOM 6393  C CZ  . ARG C 1 91  ? -21.964 -36.032 -24.524 1.00 128.69 ? 91  ARG C CZ  1 
ATOM 6394  N NH1 . ARG C 1 91  ? -22.037 -34.724 -24.346 1.00 123.09 ? 91  ARG C NH1 1 
ATOM 6395  N NH2 . ARG C 1 91  ? -21.894 -36.530 -25.744 1.00 117.16 ? 91  ARG C NH2 1 
ATOM 6396  N N   . ASN C 1 92  ? -19.844 -41.290 -21.937 1.00 116.24 ? 92  ASN C N   1 
ATOM 6397  C CA  . ASN C 1 92  ? -19.198 -42.381 -22.703 1.00 107.11 ? 92  ASN C CA  1 
ATOM 6398  C C   . ASN C 1 92  ? -18.838 -41.821 -24.075 1.00 104.70 ? 92  ASN C C   1 
ATOM 6399  O O   . ASN C 1 92  ? -19.711 -41.238 -24.730 1.00 101.55 ? 92  ASN C O   1 
ATOM 6400  C CB  . ASN C 1 92  ? -20.058 -43.641 -22.792 1.00 100.67 ? 92  ASN C CB  1 
ATOM 6401  C CG  . ASN C 1 92  ? -21.387 -43.440 -23.490 1.00 101.28 ? 92  ASN C CG  1 
ATOM 6402  O OD1 . ASN C 1 92  ? -21.791 -42.315 -23.766 1.00 106.82 ? 92  ASN C OD1 1 
ATOM 6403  N ND2 . ASN C 1 92  ? -22.089 -44.531 -23.752 1.00 94.59  ? 92  ASN C ND2 1 
ATOM 6404  N N   . ALA C 1 93  ? -17.577 -41.971 -24.466 1.00 103.28 ? 93  ALA C N   1 
ATOM 6405  C CA  . ALA C 1 93  ? -17.158 -41.499 -25.796 1.00 94.01  ? 93  ALA C CA  1 
ATOM 6406  C C   . ALA C 1 93  ? -17.785 -42.442 -26.812 1.00 88.95  ? 93  ALA C C   1 
ATOM 6407  O O   . ALA C 1 93  ? -17.695 -42.173 -28.012 1.00 91.04  ? 93  ALA C O   1 
ATOM 6408  C CB  . ALA C 1 93  ? -15.665 -41.495 -25.874 1.00 91.55  ? 93  ALA C CB  1 
ATOM 6409  N N   . PHE C 1 94  ? -18.413 -43.516 -26.325 1.00 84.00  ? 94  PHE C N   1 
ATOM 6410  C CA  . PHE C 1 94  ? -19.132 -44.425 -27.252 1.00 75.64  ? 94  PHE C CA  1 
ATOM 6411  C C   . PHE C 1 94  ? -19.964 -43.560 -28.204 1.00 72.07  ? 94  PHE C C   1 
ATOM 6412  O O   . PHE C 1 94  ? -20.089 -43.929 -29.387 1.00 67.77  ? 94  PHE C O   1 
ATOM 6413  C CB  . PHE C 1 94  ? -19.998 -45.415 -26.473 1.00 74.00  ? 94  PHE C CB  1 
ATOM 6414  C CG  . PHE C 1 94  ? -20.292 -46.705 -27.199 1.00 66.58  ? 94  PHE C CG  1 
ATOM 6415  C CD1 . PHE C 1 94  ? -19.714 -46.976 -28.429 1.00 65.27  ? 94  PHE C CD1 1 
ATOM 6416  C CD2 . PHE C 1 94  ? -21.147 -47.650 -26.653 1.00 65.64  ? 94  PHE C CD2 1 
ATOM 6417  C CE1 . PHE C 1 94  ? -19.984 -48.160 -29.095 1.00 67.63  ? 94  PHE C CE1 1 
ATOM 6418  C CE2 . PHE C 1 94  ? -21.416 -48.834 -27.319 1.00 56.20  ? 94  PHE C CE2 1 
ATOM 6419  C CZ  . PHE C 1 94  ? -20.836 -49.087 -28.540 1.00 68.33  ? 94  PHE C CZ  1 
ATOM 6420  N N   . GLU C 1 95  ? -20.495 -42.438 -27.703 1.00 73.00  ? 95  GLU C N   1 
ATOM 6421  C CA  . GLU C 1 95  ? -21.363 -41.597 -28.562 1.00 82.10  ? 95  GLU C CA  1 
ATOM 6422  C C   . GLU C 1 95  ? -20.488 -40.788 -29.515 1.00 82.03  ? 95  GLU C C   1 
ATOM 6423  O O   . GLU C 1 95  ? -21.011 -39.859 -30.145 1.00 82.18  ? 95  GLU C O   1 
ATOM 6424  C CB  . GLU C 1 95  ? -22.242 -40.697 -27.697 1.00 81.75  ? 95  GLU C CB  1 
ATOM 6425  C CG  . GLU C 1 95  ? -23.389 -41.440 -27.037 1.00 85.41  ? 95  GLU C CG  1 
ATOM 6426  C CD  . GLU C 1 95  ? -24.481 -41.906 -27.984 1.00 86.98  ? 95  GLU C CD  1 
ATOM 6427  O OE1 . GLU C 1 95  ? -24.376 -41.625 -29.192 1.00 84.39  ? 95  GLU C OE1 1 
ATOM 6428  O OE2 . GLU C 1 95  ? -25.438 -42.548 -27.511 1.00 80.25  ? 95  GLU C OE2 1 
ATOM 6429  N N   . THR C 1 96  ? -19.206 -41.136 -29.605 1.00 80.08  ? 96  THR C N   1 
ATOM 6430  C CA  . THR C 1 96  ? -18.289 -40.411 -30.511 1.00 81.03  ? 96  THR C CA  1 
ATOM 6431  C C   . THR C 1 96  ? -17.601 -41.414 -31.433 1.00 78.27  ? 96  THR C C   1 
ATOM 6432  O O   . THR C 1 96  ? -17.060 -40.995 -32.460 1.00 76.16  ? 96  THR C O   1 
ATOM 6433  C CB  . THR C 1 96  ? -17.277 -39.609 -29.693 1.00 87.76  ? 96  THR C CB  1 
ATOM 6434  O OG1 . THR C 1 96  ? -16.347 -40.530 -29.125 1.00 84.14  ? 96  THR C OG1 1 
ATOM 6435  C CG2 . THR C 1 96  ? -17.926 -38.791 -28.598 1.00 94.13  ? 96  THR C CG2 1 
ATOM 6436  N N   . ALA C 1 97  ? -17.644 -42.692 -31.079 1.00 70.57  ? 97  ALA C N   1 
ATOM 6437  C CA  . ALA C 1 97  ? -16.922 -43.712 -31.865 1.00 67.17  ? 97  ALA C CA  1 
ATOM 6438  C C   . ALA C 1 97  ? -17.802 -44.135 -33.028 1.00 61.29  ? 97  ALA C C   1 
ATOM 6439  O O   . ALA C 1 97  ? -17.634 -45.246 -33.527 1.00 57.17  ? 97  ALA C O   1 
ATOM 6440  C CB  . ALA C 1 97  ? -16.600 -44.883 -30.990 1.00 71.74  ? 97  ALA C CB  1 
ATOM 6441  N N   . GLY C 1 98  ? -18.711 -43.265 -33.428 1.00 61.26  ? 98  GLY C N   1 
ATOM 6442  C CA  . GLY C 1 98  ? -19.515 -43.600 -34.606 1.00 53.23  ? 98  GLY C CA  1 
ATOM 6443  C C   . GLY C 1 98  ? -18.596 -43.934 -35.754 1.00 52.49  ? 98  GLY C C   1 
ATOM 6444  O O   . GLY C 1 98  ? -18.538 -45.106 -36.145 1.00 51.45  ? 98  GLY C O   1 
ATOM 6445  N N   . PRO C 1 99  ? -17.872 -42.947 -36.311 1.00 48.20  ? 99  PRO C N   1 
ATOM 6446  C CA  . PRO C 1 99  ? -17.030 -43.221 -37.489 1.00 53.42  ? 99  PRO C CA  1 
ATOM 6447  C C   . PRO C 1 99  ? -16.033 -44.346 -37.279 1.00 52.21  ? 99  PRO C C   1 
ATOM 6448  O O   . PRO C 1 99  ? -15.631 -44.994 -38.256 1.00 50.63  ? 99  PRO C O   1 
ATOM 6449  C CB  . PRO C 1 99  ? -16.326 -41.878 -37.742 1.00 49.18  ? 99  PRO C CB  1 
ATOM 6450  C CG  . PRO C 1 99  ? -16.496 -41.096 -36.476 1.00 56.82  ? 99  PRO C CG  1 
ATOM 6451  C CD  . PRO C 1 99  ? -17.799 -41.536 -35.900 1.00 57.69  ? 99  PRO C CD  1 
ATOM 6452  N N   . THR C 1 100 ? -15.630 -44.621 -36.039 1.00 54.98  ? 100 THR C N   1 
ATOM 6453  C CA  . THR C 1 100 ? -14.762 -45.768 -35.789 1.00 56.64  ? 100 THR C CA  1 
ATOM 6454  C C   . THR C 1 100 ? -15.485 -47.071 -36.106 1.00 58.08  ? 100 THR C C   1 
ATOM 6455  O O   . THR C 1 100 ? -14.944 -47.950 -36.790 1.00 54.10  ? 100 THR C O   1 
ATOM 6456  C CB  . THR C 1 100 ? -14.283 -45.757 -34.340 1.00 50.86  ? 100 THR C CB  1 
ATOM 6457  O OG1 . THR C 1 100 ? -13.823 -44.444 -33.998 1.00 58.67  ? 100 THR C OG1 1 
ATOM 6458  C CG2 . THR C 1 100 ? -13.144 -46.747 -34.157 1.00 45.02  ? 100 THR C CG2 1 
ATOM 6459  N N   . PHE C 1 101 ? -16.721 -47.208 -35.626 1.00 55.59  ? 101 PHE C N   1 
ATOM 6460  C CA  . PHE C 1 101 ? -17.510 -48.387 -35.963 1.00 51.99  ? 101 PHE C CA  1 
ATOM 6461  C C   . PHE C 1 101 ? -17.868 -48.405 -37.443 1.00 55.11  ? 101 PHE C C   1 
ATOM 6462  O O   . PHE C 1 101 ? -18.010 -49.484 -38.032 1.00 55.27  ? 101 PHE C O   1 
ATOM 6463  C CB  . PHE C 1 101 ? -18.769 -48.437 -35.101 1.00 41.64  ? 101 PHE C CB  1 
ATOM 6464  C CG  . PHE C 1 101 ? -19.545 -49.714 -35.237 1.00 45.58  ? 101 PHE C CG  1 
ATOM 6465  C CD1 . PHE C 1 101 ? -18.965 -50.929 -34.914 1.00 47.31  ? 101 PHE C CD1 1 
ATOM 6466  C CD2 . PHE C 1 101 ? -20.858 -49.696 -35.677 1.00 45.03  ? 101 PHE C CD2 1 
ATOM 6467  C CE1 . PHE C 1 101 ? -19.678 -52.105 -35.034 1.00 48.19  ? 101 PHE C CE1 1 
ATOM 6468  C CE2 . PHE C 1 101 ? -21.576 -50.867 -35.796 1.00 39.97  ? 101 PHE C CE2 1 
ATOM 6469  C CZ  . PHE C 1 101 ? -20.986 -52.074 -35.475 1.00 39.79  ? 101 PHE C CZ  1 
ATOM 6470  N N   . SER C 1 102 ? -18.012 -47.231 -38.059 1.00 53.05  ? 102 SER C N   1 
ATOM 6471  C CA  . SER C 1 102 ? -18.213 -47.176 -39.502 1.00 46.41  ? 102 SER C CA  1 
ATOM 6472  C C   . SER C 1 102 ? -17.018 -47.770 -40.238 1.00 50.12  ? 102 SER C C   1 
ATOM 6473  O O   . SER C 1 102 ? -17.187 -48.531 -41.194 1.00 39.77  ? 102 SER C O   1 
ATOM 6474  C CB  . SER C 1 102 ? -18.458 -45.734 -39.948 1.00 52.03  ? 102 SER C CB  1 
ATOM 6475  O OG  . SER C 1 102 ? -18.658 -45.663 -41.348 1.00 44.46  ? 102 SER C OG  1 
ATOM 6476  N N   . GLU C 1 103 ? -15.803 -47.437 -39.795 1.00 59.18  ? 103 GLU C N   1 
ATOM 6477  C CA  . GLU C 1 103 ? -14.602 -48.028 -40.376 1.00 56.31  ? 103 GLU C CA  1 
ATOM 6478  C C   . GLU C 1 103 ? -14.556 -49.534 -40.141 1.00 52.71  ? 103 GLU C C   1 
ATOM 6479  O O   . GLU C 1 103 ? -14.169 -50.305 -41.032 1.00 50.78  ? 103 GLU C O   1 
ATOM 6480  C CB  . GLU C 1 103 ? -13.359 -47.357 -39.791 1.00 62.87  ? 103 GLU C CB  1 
ATOM 6481  C CG  . GLU C 1 103 ? -12.049 -47.796 -40.418 1.00 76.74  ? 103 GLU C CG  1 
ATOM 6482  C CD  . GLU C 1 103 ? -11.813 -47.167 -41.779 1.00 79.61  ? 103 GLU C CD  1 
ATOM 6483  O OE1 . GLU C 1 103 ? -12.482 -46.159 -42.094 1.00 69.14  ? 103 GLU C OE1 1 
ATOM 6484  O OE2 . GLU C 1 103 ? -10.958 -47.679 -42.529 1.00 77.50  ? 103 GLU C OE2 1 
ATOM 6485  N N   . ILE C 1 104 ? -14.942 -49.973 -38.940 1.00 59.93  ? 104 ILE C N   1 
ATOM 6486  C CA  . ILE C 1 104 ? -14.943 -51.406 -38.643 1.00 56.76  ? 104 ILE C CA  1 
ATOM 6487  C C   . ILE C 1 104 ? -15.892 -52.146 -39.580 1.00 53.43  ? 104 ILE C C   1 
ATOM 6488  O O   . ILE C 1 104 ? -15.552 -53.198 -40.133 1.00 53.15  ? 104 ILE C O   1 
ATOM 6489  C CB  . ILE C 1 104 ? -15.292 -51.650 -37.163 1.00 50.04  ? 104 ILE C CB  1 
ATOM 6490  C CG1 . ILE C 1 104 ? -14.072 -51.374 -36.281 1.00 46.60  ? 104 ILE C CG1 1 
ATOM 6491  C CG2 . ILE C 1 104 ? -15.793 -53.070 -36.954 1.00 47.31  ? 104 ILE C CG2 1 
ATOM 6492  C CD1 . ILE C 1 104 ? -14.243 -51.788 -34.839 1.00 58.77  ? 104 ILE C CD1 1 
ATOM 6493  N N   . LEU C 1 105 ? -17.097 -51.604 -39.777 1.00 51.29  ? 105 LEU C N   1 
ATOM 6494  C CA  . LEU C 1 105 ? -18.044 -52.230 -40.696 1.00 45.79  ? 105 LEU C CA  1 
ATOM 6495  C C   . LEU C 1 105 ? -17.567 -52.138 -42.139 1.00 46.36  ? 105 LEU C C   1 
ATOM 6496  O O   . LEU C 1 105 ? -17.833 -53.044 -42.938 1.00 49.39  ? 105 LEU C O   1 
ATOM 6497  C CB  . LEU C 1 105 ? -19.425 -51.590 -40.561 1.00 43.27  ? 105 LEU C CB  1 
ATOM 6498  C CG  . LEU C 1 105 ? -20.147 -51.710 -39.217 1.00 45.43  ? 105 LEU C CG  1 
ATOM 6499  C CD1 . LEU C 1 105 ? -21.523 -51.066 -39.312 1.00 38.64  ? 105 LEU C CD1 1 
ATOM 6500  C CD2 . LEU C 1 105 ? -20.259 -53.161 -38.778 1.00 42.44  ? 105 LEU C CD2 1 
ATOM 6501  N N   . LYS C 1 106 ? -16.871 -51.056 -42.490 1.00 50.60  ? 106 LYS C N   1 
ATOM 6502  C CA  . LYS C 1 106 ? -16.322 -50.917 -43.833 1.00 48.74  ? 106 LYS C CA  1 
ATOM 6503  C C   . LYS C 1 106 ? -15.293 -52.000 -44.117 1.00 51.65  ? 106 LYS C C   1 
ATOM 6504  O O   . LYS C 1 106 ? -15.201 -52.501 -45.243 1.00 52.32  ? 106 LYS C O   1 
ATOM 6505  C CB  . LYS C 1 106 ? -15.703 -49.526 -43.986 1.00 50.94  ? 106 LYS C CB  1 
ATOM 6506  C CG  . LYS C 1 106 ? -15.464 -49.081 -45.410 1.00 52.97  ? 106 LYS C CG  1 
ATOM 6507  C CD  . LYS C 1 106 ? -14.906 -47.667 -45.431 1.00 62.90  ? 106 LYS C CD  1 
ATOM 6508  C CE  . LYS C 1 106 ? -13.472 -47.623 -44.922 1.00 74.89  ? 106 LYS C CE  1 
ATOM 6509  N NZ  . LYS C 1 106 ? -12.522 -48.303 -45.848 1.00 73.71  ? 106 LYS C NZ  1 
ATOM 6510  N N   . THR C 1 107 ? -14.579 -52.420 -43.071 1.00 52.16  ? 107 THR C N   1 
ATOM 6511  C CA  . THR C 1 107 ? -13.599 -53.528 -43.225 1.00 54.76  ? 107 THR C CA  1 
ATOM 6512  C C   . THR C 1 107 ? -14.331 -54.869 -43.110 1.00 60.87  ? 107 THR C C   1 
ATOM 6513  O O   . THR C 1 107 ? -14.186 -55.696 -44.029 1.00 64.36  ? 107 THR C O   1 
ATOM 6514  C CB  . THR C 1 107 ? -12.480 -53.419 -42.185 1.00 53.64  ? 107 THR C CB  1 
ATOM 6515  O OG1 . THR C 1 107 ? -11.860 -52.141 -42.333 1.00 50.54  ? 107 THR C OG1 1 
ATOM 6516  C CG2 . THR C 1 107 ? -11.443 -54.513 -42.318 1.00 46.68  ? 107 THR C CG2 1 
ATOM 6517  N N   . LEU C 1 108 ? -15.090 -55.071 -42.025 1.00 55.34  ? 108 LEU C N   1 
ATOM 6518  C CA  . LEU C 1 108 ? -15.785 -56.367 -41.797 1.00 52.64  ? 108 LEU C CA  1 
ATOM 6519  C C   . LEU C 1 108 ? -16.902 -56.563 -42.827 1.00 58.13  ? 108 LEU C C   1 
ATOM 6520  O O   . LEU C 1 108 ? -16.964 -57.656 -43.422 1.00 57.56  ? 108 LEU C O   1 
ATOM 6521  C CB  . LEU C 1 108 ? -16.354 -56.380 -40.376 1.00 58.00  ? 108 LEU C CB  1 
ATOM 6522  C CG  . LEU C 1 108 ? -15.321 -56.302 -39.252 1.00 57.20  ? 108 LEU C CG  1 
ATOM 6523  C CD1 . LEU C 1 108 ? -15.899 -56.836 -37.953 1.00 51.67  ? 108 LEU C CD1 1 
ATOM 6524  C CD2 . LEU C 1 108 ? -14.057 -57.058 -39.626 1.00 59.10  ? 108 LEU C CD2 1 
ATOM 6525  N N   . ASN C 1 109 ? -17.748 -55.547 -43.020 1.00 63.22  ? 109 ASN C N   1 
ATOM 6526  C CA  . ASN C 1 109 ? -18.897 -55.664 -43.964 1.00 58.08  ? 109 ASN C CA  1 
ATOM 6527  C C   . ASN C 1 109 ? -19.714 -56.914 -43.607 1.00 55.96  ? 109 ASN C C   1 
ATOM 6528  O O   . ASN C 1 109 ? -19.743 -57.855 -44.425 1.00 54.00  ? 109 ASN C O   1 
ATOM 6529  C CB  . ASN C 1 109 ? -18.431 -55.678 -45.423 1.00 61.60  ? 109 ASN C CB  1 
ATOM 6530  C CG  . ASN C 1 109 ? -19.555 -55.418 -46.403 1.00 78.80  ? 109 ASN C CG  1 
ATOM 6531  O OD1 . ASN C 1 109 ? -20.526 -56.166 -46.458 1.00 80.63  ? 109 ASN C OD1 1 
ATOM 6532  N ND2 . ASN C 1 109 ? -19.429 -54.356 -47.182 1.00 73.88  ? 109 ASN C ND2 1 
ATOM 6533  N N   . PRO C 1 110 ? -20.371 -56.966 -42.427 1.00 47.26  ? 110 PRO C N   1 
ATOM 6534  C CA  . PRO C 1 110 ? -21.199 -58.115 -42.044 1.00 51.28  ? 110 PRO C CA  1 
ATOM 6535  C C   . PRO C 1 110 ? -22.522 -58.145 -42.823 1.00 53.13  ? 110 PRO C C   1 
ATOM 6536  O O   . PRO C 1 110 ? -22.959 -57.099 -43.268 1.00 55.03  ? 110 PRO C O   1 
ATOM 6537  C CB  . PRO C 1 110 ? -21.480 -57.864 -40.557 1.00 50.75  ? 110 PRO C CB  1 
ATOM 6538  C CG  . PRO C 1 110 ? -21.450 -56.358 -40.438 1.00 42.95  ? 110 PRO C CG  1 
ATOM 6539  C CD  . PRO C 1 110 ? -20.365 -55.922 -41.399 1.00 41.35  ? 110 PRO C CD  1 
ATOM 6540  N N   . ASP C 1 111 ? -23.122 -59.332 -42.959 1.00 53.16  ? 111 ASP C N   1 
ATOM 6541  C CA  . ASP C 1 111 ? -24.416 -59.466 -43.685 1.00 45.33  ? 111 ASP C CA  1 
ATOM 6542  C C   . ASP C 1 111 ? -25.545 -58.934 -42.799 1.00 51.20  ? 111 ASP C C   1 
ATOM 6543  O O   . ASP C 1 111 ? -26.683 -58.838 -43.300 1.00 51.48  ? 111 ASP C O   1 
ATOM 6544  C CB  . ASP C 1 111 ? -24.679 -60.919 -44.086 1.00 52.93  ? 111 ASP C CB  1 
ATOM 6545  C CG  . ASP C 1 111 ? -23.542 -61.549 -44.874 1.00 58.27  ? 111 ASP C CG  1 
ATOM 6546  O OD1 . ASP C 1 111 ? -22.554 -60.838 -45.148 1.00 57.19  ? 111 ASP C OD1 1 
ATOM 6547  O OD2 . ASP C 1 111 ? -23.649 -62.748 -45.199 1.00 63.42  ? 111 ASP C OD2 1 
ATOM 6548  N N   . LEU C 1 112 ? -25.243 -58.602 -41.542 1.00 44.00  ? 112 LEU C N   1 
ATOM 6549  C CA  . LEU C 1 112 ? -26.270 -58.146 -40.616 1.00 39.73  ? 112 LEU C CA  1 
ATOM 6550  C C   . LEU C 1 112 ? -25.612 -57.648 -39.336 1.00 39.72  ? 112 LEU C C   1 
ATOM 6551  O O   . LEU C 1 112 ? -24.558 -58.144 -38.932 1.00 45.21  ? 112 LEU C O   1 
ATOM 6552  C CB  . LEU C 1 112 ? -27.271 -59.267 -40.310 1.00 46.21  ? 112 LEU C CB  1 
ATOM 6553  C CG  . LEU C 1 112 ? -28.555 -58.901 -39.568 1.00 50.35  ? 112 LEU C CG  1 
ATOM 6554  C CD1 . LEU C 1 112 ? -29.710 -59.719 -40.110 1.00 45.56  ? 112 LEU C CD1 1 
ATOM 6555  C CD2 . LEU C 1 112 ? -28.398 -59.128 -38.073 1.00 43.37  ? 112 LEU C CD2 1 
ATOM 6556  N N   . LEU C 1 113 ? -26.251 -56.668 -38.701 1.00 35.81  ? 113 LEU C N   1 
ATOM 6557  C CA  . LEU C 1 113 ? -25.771 -56.093 -37.454 1.00 40.42  ? 113 LEU C CA  1 
ATOM 6558  C C   . LEU C 1 113 ? -26.804 -56.302 -36.354 1.00 41.20  ? 113 LEU C C   1 
ATOM 6559  O O   . LEU C 1 113 ? -28.005 -56.111 -36.572 1.00 38.51  ? 113 LEU C O   1 
ATOM 6560  C CB  . LEU C 1 113 ? -25.478 -54.597 -37.612 1.00 34.59  ? 113 LEU C CB  1 
ATOM 6561  C CG  . LEU C 1 113 ? -25.130 -53.842 -36.328 1.00 40.43  ? 113 LEU C CG  1 
ATOM 6562  C CD1 . LEU C 1 113 ? -23.848 -54.382 -35.714 1.00 33.21  ? 113 LEU C CD1 1 
ATOM 6563  C CD2 . LEU C 1 113 ? -25.016 -52.348 -36.583 1.00 44.55  ? 113 LEU C CD2 1 
ATOM 6564  N N   . ILE C 1 114 ? -26.332 -56.695 -35.172 1.00 34.71  ? 114 ILE C N   1 
ATOM 6565  C CA  . ILE C 1 114 ? -27.175 -56.860 -33.991 1.00 33.23  ? 114 ILE C CA  1 
ATOM 6566  C C   . ILE C 1 114 ? -26.684 -55.873 -32.938 1.00 34.81  ? 114 ILE C C   1 
ATOM 6567  O O   . ILE C 1 114 ? -25.615 -56.068 -32.344 1.00 40.27  ? 114 ILE C O   1 
ATOM 6568  C CB  . ILE C 1 114 ? -27.151 -58.297 -33.459 1.00 33.02  ? 114 ILE C CB  1 
ATOM 6569  C CG1 . ILE C 1 114 ? -27.714 -59.260 -34.503 1.00 37.05  ? 114 ILE C CG1 1 
ATOM 6570  C CG2 . ILE C 1 114 ? -27.937 -58.392 -32.164 1.00 33.92  ? 114 ILE C CG2 1 
ATOM 6571  C CD1 . ILE C 1 114 ? -27.756 -60.706 -34.055 1.00 33.22  ? 114 ILE C CD1 1 
ATOM 6572  N N   . TYR C 1 115 ? -27.469 -54.830 -32.697 1.00 32.70  ? 115 TYR C N   1 
ATOM 6573  C CA  . TYR C 1 115 ? -27.077 -53.714 -31.847 1.00 37.09  ? 115 TYR C CA  1 
ATOM 6574  C C   . TYR C 1 115 ? -27.853 -53.733 -30.535 1.00 42.15  ? 115 TYR C C   1 
ATOM 6575  O O   . TYR C 1 115 ? -28.832 -54.465 -30.367 1.00 38.70  ? 115 TYR C O   1 
ATOM 6576  C CB  . TYR C 1 115 ? -27.286 -52.384 -32.581 1.00 48.22  ? 115 TYR C CB  1 
ATOM 6577  C CG  . TYR C 1 115 ? -28.721 -52.088 -32.956 1.00 39.98  ? 115 TYR C CG  1 
ATOM 6578  C CD1 . TYR C 1 115 ? -29.301 -52.648 -34.091 1.00 38.88  ? 115 TYR C CD1 1 
ATOM 6579  C CD2 . TYR C 1 115 ? -29.492 -51.227 -32.187 1.00 40.97  ? 115 TYR C CD2 1 
ATOM 6580  C CE1 . TYR C 1 115 ? -30.614 -52.372 -34.435 1.00 45.81  ? 115 TYR C CE1 1 
ATOM 6581  C CE2 . TYR C 1 115 ? -30.801 -50.943 -32.522 1.00 48.66  ? 115 TYR C CE2 1 
ATOM 6582  C CZ  . TYR C 1 115 ? -31.357 -51.516 -33.647 1.00 50.72  ? 115 TYR C CZ  1 
ATOM 6583  O OH  . TYR C 1 115 ? -32.665 -51.235 -33.978 1.00 38.44  ? 115 TYR C OH  1 
ATOM 6584  N N   . ASP C 1 116 ? -27.394 -52.909 -29.596 1.00 54.32  ? 116 ASP C N   1 
ATOM 6585  C CA  . ASP C 1 116 ? -27.997 -52.819 -28.275 1.00 45.78  ? 116 ASP C CA  1 
ATOM 6586  C C   . ASP C 1 116 ? -28.868 -51.568 -28.177 1.00 48.32  ? 116 ASP C C   1 
ATOM 6587  O O   . ASP C 1 116 ? -29.368 -51.068 -29.189 1.00 50.23  ? 116 ASP C O   1 
ATOM 6588  C CB  . ASP C 1 116 ? -26.901 -52.828 -27.200 1.00 50.18  ? 116 ASP C CB  1 
ATOM 6589  C CG  . ASP C 1 116 ? -27.338 -53.508 -25.919 1.00 52.21  ? 116 ASP C CG  1 
ATOM 6590  O OD1 . ASP C 1 116 ? -28.553 -53.531 -25.645 1.00 61.11  ? 116 ASP C OD1 1 
ATOM 6591  O OD2 . ASP C 1 116 ? -26.466 -54.020 -25.187 1.00 44.88  ? 116 ASP C OD2 1 
ATOM 6592  N N   . PHE C 1 117 ? -29.048 -51.042 -26.966 1.00 49.61  ? 117 PHE C N   1 
ATOM 6593  C CA  . PHE C 1 117 ? -30.048 -50.003 -26.748 1.00 47.10  ? 117 PHE C CA  1 
ATOM 6594  C C   . PHE C 1 117 ? -29.486 -48.592 -26.806 1.00 48.38  ? 117 PHE C C   1 
ATOM 6595  O O   . PHE C 1 117 ? -30.200 -47.663 -27.207 1.00 54.79  ? 117 PHE C O   1 
ATOM 6596  C CB  . PHE C 1 117 ? -30.736 -50.205 -25.397 1.00 48.70  ? 117 PHE C CB  1 
ATOM 6597  C CG  . PHE C 1 117 ? -29.830 -50.003 -24.212 1.00 53.10  ? 117 PHE C CG  1 
ATOM 6598  C CD1 . PHE C 1 117 ? -29.013 -51.028 -23.768 1.00 53.96  ? 117 PHE C CD1 1 
ATOM 6599  C CD2 . PHE C 1 117 ? -29.808 -48.793 -23.535 1.00 47.77  ? 117 PHE C CD2 1 
ATOM 6600  C CE1 . PHE C 1 117 ? -28.185 -50.851 -22.677 1.00 54.55  ? 117 PHE C CE1 1 
ATOM 6601  C CE2 . PHE C 1 117 ? -28.980 -48.609 -22.443 1.00 56.42  ? 117 PHE C CE2 1 
ATOM 6602  C CZ  . PHE C 1 117 ? -28.169 -49.641 -22.014 1.00 57.37  ? 117 PHE C CZ  1 
ATOM 6603  N N   . ASN C 1 118 ? -28.238 -48.405 -26.407 1.00 52.42  ? 118 ASN C N   1 
ATOM 6604  C CA  . ASN C 1 118 ? -27.700 -47.061 -26.242 1.00 66.73  ? 118 ASN C CA  1 
ATOM 6605  C C   . ASN C 1 118 ? -26.723 -46.600 -27.322 1.00 62.98  ? 118 ASN C C   1 
ATOM 6606  O O   . ASN C 1 118 ? -26.534 -45.385 -27.460 1.00 68.80  ? 118 ASN C O   1 
ATOM 6607  C CB  . ASN C 1 118 ? -27.007 -46.923 -24.886 1.00 58.74  ? 118 ASN C CB  1 
ATOM 6608  C CG  . ASN C 1 118 ? -26.996 -45.490 -24.399 1.00 64.11  ? 118 ASN C CG  1 
ATOM 6609  O OD1 . ASN C 1 118 ? -27.932 -44.737 -24.667 1.00 76.38  ? 118 ASN C OD1 1 
ATOM 6610  N ND2 . ASN C 1 118 ? -25.939 -45.099 -23.695 1.00 68.50  ? 118 ASN C ND2 1 
ATOM 6611  N N   . PRO C 1 119 ? -26.045 -47.494 -28.061 1.00 47.72  ? 119 PRO C N   1 
ATOM 6612  C CA  . PRO C 1 119 ? -25.189 -47.013 -29.163 1.00 49.52  ? 119 PRO C CA  1 
ATOM 6613  C C   . PRO C 1 119 ? -25.843 -45.969 -30.067 1.00 53.57  ? 119 PRO C C   1 
ATOM 6614  O O   . PRO C 1 119 ? -25.127 -45.137 -30.640 1.00 64.17  ? 119 PRO C O   1 
ATOM 6615  C CB  . PRO C 1 119 ? -24.839 -48.311 -29.904 1.00 55.42  ? 119 PRO C CB  1 
ATOM 6616  C CG  . PRO C 1 119 ? -24.705 -49.312 -28.790 1.00 49.76  ? 119 PRO C CG  1 
ATOM 6617  C CD  . PRO C 1 119 ? -25.746 -48.904 -27.744 1.00 42.56  ? 119 PRO C CD  1 
ATOM 6618  N N   . SER C 1 120 ? -27.172 -45.934 -30.173 1.00 50.62  ? 120 SER C N   1 
ATOM 6619  C CA  . SER C 1 120 ? -27.882 -44.851 -30.921 1.00 62.29  ? 120 SER C CA  1 
ATOM 6620  C C   . SER C 1 120 ? -27.506 -44.759 -32.406 1.00 59.26  ? 120 SER C C   1 
ATOM 6621  O O   . SER C 1 120 ? -28.407 -44.848 -33.249 1.00 48.49  ? 120 SER C O   1 
ATOM 6622  C CB  . SER C 1 120 ? -27.660 -43.527 -30.261 1.00 72.71  ? 120 SER C CB  1 
ATOM 6623  O OG  . SER C 1 120 ? -28.060 -42.463 -31.107 1.00 70.54  ? 120 SER C OG  1 
ATOM 6624  N N   . TRP C 1 121 ? -26.235 -44.521 -32.709 1.00 58.77  ? 121 TRP C N   1 
ATOM 6625  C CA  . TRP C 1 121 ? -25.797 -44.337 -34.113 1.00 48.32  ? 121 TRP C CA  1 
ATOM 6626  C C   . TRP C 1 121 ? -25.674 -45.688 -34.807 1.00 50.39  ? 121 TRP C C   1 
ATOM 6627  O O   . TRP C 1 121 ? -25.571 -45.715 -36.037 1.00 57.68  ? 121 TRP C O   1 
ATOM 6628  C CB  . TRP C 1 121 ? -24.479 -43.564 -34.145 1.00 64.37  ? 121 TRP C CB  1 
ATOM 6629  C CG  . TRP C 1 121 ? -23.433 -44.009 -33.169 1.00 58.82  ? 121 TRP C CG  1 
ATOM 6630  C CD1 . TRP C 1 121 ? -22.967 -43.305 -32.097 1.00 44.79  ? 121 TRP C CD1 1 
ATOM 6631  C CD2 . TRP C 1 121 ? -22.673 -45.228 -33.205 1.00 53.52  ? 121 TRP C CD2 1 
ATOM 6632  N NE1 . TRP C 1 121 ? -21.995 -44.015 -31.446 1.00 48.62  ? 121 TRP C NE1 1 
ATOM 6633  C CE2 . TRP C 1 121 ? -21.792 -45.198 -32.104 1.00 45.48  ? 121 TRP C CE2 1 
ATOM 6634  C CE3 . TRP C 1 121 ? -22.658 -46.345 -34.045 1.00 53.50  ? 121 TRP C CE3 1 
ATOM 6635  C CZ2 . TRP C 1 121 ? -20.912 -46.241 -31.826 1.00 45.89  ? 121 TRP C CZ2 1 
ATOM 6636  C CZ3 . TRP C 1 121 ? -21.790 -47.376 -33.767 1.00 52.81  ? 121 TRP C CZ3 1 
ATOM 6637  C CH2 . TRP C 1 121 ? -20.930 -47.323 -32.674 1.00 42.75  ? 121 TRP C CH2 1 
ATOM 6638  N N   . ALA C 1 122 ? -25.698 -46.765 -34.036 1.00 47.92  ? 122 ALA C N   1 
ATOM 6639  C CA  . ALA C 1 122 ? -25.514 -48.108 -34.615 1.00 49.51  ? 122 ALA C CA  1 
ATOM 6640  C C   . ALA C 1 122 ? -26.497 -48.305 -35.760 1.00 44.19  ? 122 ALA C C   1 
ATOM 6641  O O   . ALA C 1 122 ? -26.051 -48.616 -36.865 1.00 45.24  ? 122 ALA C O   1 
ATOM 6642  C CB  . ALA C 1 122 ? -25.718 -49.133 -33.538 1.00 51.27  ? 122 ALA C CB  1 
ATOM 6643  N N   . PRO C 1 123 ? -27.811 -48.134 -35.547 1.00 44.00  ? 123 PRO C N   1 
ATOM 6644  C CA  . PRO C 1 123 ? -28.768 -48.401 -36.610 1.00 49.49  ? 123 PRO C CA  1 
ATOM 6645  C C   . PRO C 1 123 ? -28.526 -47.476 -37.813 1.00 51.54  ? 123 PRO C C   1 
ATOM 6646  O O   . PRO C 1 123 ? -28.682 -47.920 -38.930 1.00 44.30  ? 123 PRO C O   1 
ATOM 6647  C CB  . PRO C 1 123 ? -30.117 -48.179 -35.907 1.00 51.50  ? 123 PRO C CB  1 
ATOM 6648  C CG  . PRO C 1 123 ? -29.808 -47.279 -34.743 1.00 57.70  ? 123 PRO C CG  1 
ATOM 6649  C CD  . PRO C 1 123 ? -28.436 -47.720 -34.294 1.00 47.62  ? 123 PRO C CD  1 
ATOM 6650  N N   . GLU C 1 124 ? -28.117 -46.238 -37.560 1.00 48.62  ? 124 GLU C N   1 
ATOM 6651  C CA  . GLU C 1 124 ? -27.921 -45.245 -38.644 1.00 53.77  ? 124 GLU C CA  1 
ATOM 6652  C C   . GLU C 1 124 ? -26.672 -45.571 -39.470 1.00 56.46  ? 124 GLU C C   1 
ATOM 6653  O O   . GLU C 1 124 ? -26.767 -45.518 -40.703 1.00 47.35  ? 124 GLU C O   1 
ATOM 6654  C CB  . GLU C 1 124 ? -27.803 -43.865 -38.004 1.00 59.04  ? 124 GLU C CB  1 
ATOM 6655  C CG  . GLU C 1 124 ? -28.690 -43.688 -36.785 1.00 55.51  ? 124 GLU C CG  1 
ATOM 6656  C CD  . GLU C 1 124 ? -28.427 -42.432 -35.971 1.00 69.66  ? 124 GLU C CD  1 
ATOM 6657  O OE1 . GLU C 1 124 ? -27.552 -41.643 -36.370 1.00 77.54  ? 124 GLU C OE1 1 
ATOM 6658  O OE2 . GLU C 1 124 ? -29.091 -42.251 -34.934 1.00 79.19  ? 124 GLU C OE2 1 
ATOM 6659  N N   . ILE C 1 125 ? -25.557 -45.885 -38.817 1.00 53.11  ? 125 ILE C N   1 
ATOM 6660  C CA  . ILE C 1 125 ? -24.271 -46.176 -39.513 1.00 50.16  ? 125 ILE C CA  1 
ATOM 6661  C C   . ILE C 1 125 ? -24.407 -47.487 -40.283 1.00 51.25  ? 125 ILE C C   1 
ATOM 6662  O O   . ILE C 1 125 ? -23.780 -47.618 -41.341 1.00 53.60  ? 125 ILE C O   1 
ATOM 6663  C CB  . ILE C 1 125 ? -23.114 -46.223 -38.499 1.00 51.28  ? 125 ILE C CB  1 
ATOM 6664  C CG1 . ILE C 1 125 ? -22.527 -44.836 -38.235 1.00 54.72  ? 125 ILE C CG1 1 
ATOM 6665  C CG2 . ILE C 1 125 ? -22.040 -47.203 -38.943 1.00 56.33  ? 125 ILE C CG2 1 
ATOM 6666  C CD1 . ILE C 1 125 ? -23.421 -43.934 -37.419 1.00 62.12  ? 125 ILE C CD1 1 
ATOM 6667  N N   . ALA C 1 126 ? -25.209 -48.414 -39.770 1.00 55.06  ? 126 ALA C N   1 
ATOM 6668  C CA  . ALA C 1 126 ? -25.414 -49.708 -40.454 1.00 57.23  ? 126 ALA C CA  1 
ATOM 6669  C C   . ALA C 1 126 ? -26.158 -49.486 -41.770 1.00 55.90  ? 126 ALA C C   1 
ATOM 6670  O O   . ALA C 1 126 ? -25.833 -50.149 -42.763 1.00 50.16  ? 126 ALA C O   1 
ATOM 6671  C CB  . ALA C 1 126 ? -26.191 -50.609 -39.548 1.00 51.48  ? 126 ALA C CB  1 
ATOM 6672  N N   . SER C 1 127 ? -27.132 -48.589 -41.755 1.00 53.94  ? 127 SER C N   1 
ATOM 6673  C CA  . SER C 1 127 ? -27.928 -48.300 -42.967 1.00 52.07  ? 127 SER C CA  1 
ATOM 6674  C C   . SER C 1 127 ? -27.087 -47.524 -43.983 1.00 51.80  ? 127 SER C C   1 
ATOM 6675  O O   . SER C 1 127 ? -27.397 -47.595 -45.173 1.00 61.33  ? 127 SER C O   1 
ATOM 6676  C CB  . SER C 1 127 ? -29.161 -47.553 -42.578 1.00 58.59  ? 127 SER C CB  1 
ATOM 6677  O OG  . SER C 1 127 ? -29.817 -48.206 -41.504 1.00 80.91  ? 127 SER C OG  1 
ATOM 6678  N N   . SER C 1 128 ? -26.080 -46.799 -43.517 1.00 55.05  ? 128 SER C N   1 
ATOM 6679  C CA  . SER C 1 128 ? -25.178 -46.062 -44.425 1.00 52.65  ? 128 SER C CA  1 
ATOM 6680  C C   . SER C 1 128 ? -24.272 -47.056 -45.146 1.00 47.80  ? 128 SER C C   1 
ATOM 6681  O O   . SER C 1 128 ? -23.621 -46.666 -46.117 1.00 52.02  ? 128 SER C O   1 
ATOM 6682  C CB  . SER C 1 128 ? -24.385 -45.073 -43.657 1.00 58.22  ? 128 SER C CB  1 
ATOM 6683  O OG  . SER C 1 128 ? -23.462 -45.724 -42.803 1.00 57.31  ? 128 SER C OG  1 
ATOM 6684  N N   . HIS C 1 129 ? -24.206 -48.285 -44.660 1.00 46.71  ? 129 HIS C N   1 
ATOM 6685  C CA  . HIS C 1 129 ? -23.430 -49.326 -45.374 1.00 43.50  ? 129 HIS C CA  1 
ATOM 6686  C C   . HIS C 1 129 ? -24.426 -50.327 -45.962 1.00 52.82  ? 129 HIS C C   1 
ATOM 6687  O O   . HIS C 1 129 ? -23.995 -51.402 -46.416 1.00 50.80  ? 129 HIS C O   1 
ATOM 6688  C CB  . HIS C 1 129 ? -22.410 -49.974 -44.438 1.00 52.90  ? 129 HIS C CB  1 
ATOM 6689  C CG  . HIS C 1 129 ? -21.390 -49.055 -43.855 1.00 54.50  ? 129 HIS C CG  1 
ATOM 6690  N ND1 . HIS C 1 129 ? -20.050 -49.160 -44.157 1.00 40.26  ? 129 HIS C ND1 1 
ATOM 6691  C CD2 . HIS C 1 129 ? -21.498 -48.034 -43.004 1.00 51.48  ? 129 HIS C CD2 1 
ATOM 6692  C CE1 . HIS C 1 129 ? -19.384 -48.226 -43.502 1.00 57.82  ? 129 HIS C CE1 1 
ATOM 6693  N NE2 . HIS C 1 129 ? -20.244 -47.531 -42.795 1.00 61.17  ? 129 HIS C NE2 1 
ATOM 6694  N N   . ASN C 1 130 ? -25.717 -49.986 -45.946 1.00 56.71  ? 130 ASN C N   1 
ATOM 6695  C CA  . ASN C 1 130 ? -26.785 -50.862 -46.494 1.00 57.49  ? 130 ASN C CA  1 
ATOM 6696  C C   . ASN C 1 130 ? -26.770 -52.173 -45.717 1.00 54.05  ? 130 ASN C C   1 
ATOM 6697  O O   . ASN C 1 130 ? -26.972 -53.223 -46.335 1.00 57.26  ? 130 ASN C O   1 
ATOM 6698  C CB  . ASN C 1 130 ? -26.654 -51.009 -48.010 1.00 49.02  ? 130 ASN C CB  1 
ATOM 6699  C CG  . ASN C 1 130 ? -27.919 -51.503 -48.680 1.00 52.12  ? 130 ASN C CG  1 
ATOM 6700  O OD1 . ASN C 1 130 ? -28.975 -50.886 -48.553 1.00 67.68  ? 130 ASN C OD1 1 
ATOM 6701  N ND2 . ASN C 1 130 ? -27.821 -52.607 -49.399 1.00 50.87  ? 130 ASN C ND2 1 
ATOM 6702  N N   . ILE C 1 131 ? -26.543 -52.095 -44.405 1.00 46.17  ? 131 ILE C N   1 
ATOM 6703  C CA  . ILE C 1 131 ? -26.566 -53.292 -43.571 1.00 43.43  ? 131 ILE C CA  1 
ATOM 6704  C C   . ILE C 1 131 ? -27.862 -53.282 -42.769 1.00 42.17  ? 131 ILE C C   1 
ATOM 6705  O O   . ILE C 1 131 ? -28.112 -52.321 -42.029 1.00 44.48  ? 131 ILE C O   1 
ATOM 6706  C CB  . ILE C 1 131 ? -25.345 -53.364 -42.644 1.00 47.60  ? 131 ILE C CB  1 
ATOM 6707  C CG1 . ILE C 1 131 ? -24.052 -53.364 -43.456 1.00 49.53  ? 131 ILE C CG1 1 
ATOM 6708  C CG2 . ILE C 1 131 ? -25.411 -54.606 -41.769 1.00 49.16  ? 131 ILE C CG2 1 
ATOM 6709  C CD1 . ILE C 1 131 ? -22.813 -53.443 -42.604 1.00 51.38  ? 131 ILE C CD1 1 
ATOM 6710  N N   . PRO C 1 132 ? -28.703 -54.307 -42.877 1.00 44.09  ? 132 PRO C N   1 
ATOM 6711  C CA  . PRO C 1 132 ? -29.913 -54.351 -42.048 1.00 49.71  ? 132 PRO C CA  1 
ATOM 6712  C C   . PRO C 1 132 ? -29.561 -54.523 -40.578 1.00 46.01  ? 132 PRO C C   1 
ATOM 6713  O O   . PRO C 1 132 ? -28.690 -55.313 -40.215 1.00 44.41  ? 132 PRO C O   1 
ATOM 6714  C CB  . PRO C 1 132 ? -30.673 -55.567 -42.590 1.00 42.19  ? 132 PRO C CB  1 
ATOM 6715  C CG  . PRO C 1 132 ? -29.617 -56.422 -43.207 1.00 43.57  ? 132 PRO C CG  1 
ATOM 6716  C CD  . PRO C 1 132 ? -28.599 -55.473 -43.770 1.00 43.96  ? 132 PRO C CD  1 
ATOM 6717  N N   . ALA C 1 133 ? -30.251 -53.763 -39.734 1.00 44.13  ? 133 ALA C N   1 
ATOM 6718  C CA  . ALA C 1 133 ? -29.967 -53.707 -38.306 1.00 35.15  ? 133 ALA C CA  1 
ATOM 6719  C C   . ALA C 1 133 ? -31.114 -54.334 -37.524 1.00 35.13  ? 133 ALA C C   1 
ATOM 6720  O O   . ALA C 1 133 ? -32.276 -53.959 -37.708 1.00 46.36  ? 133 ALA C O   1 
ATOM 6721  C CB  . ALA C 1 133 ? -29.746 -52.263 -37.857 1.00 38.80  ? 133 ALA C CB  1 
ATOM 6722  N N   . VAL C 1 134 ? -30.780 -55.286 -36.654 1.00 35.33  ? 134 VAL C N   1 
ATOM 6723  C CA  . VAL C 1 134 ? -31.746 -55.968 -35.800 1.00 38.23  ? 134 VAL C CA  1 
ATOM 6724  C C   . VAL C 1 134 ? -31.398 -55.674 -34.346 1.00 29.07  ? 134 VAL C C   1 
ATOM 6725  O O   . VAL C 1 134 ? -30.229 -55.735 -33.954 1.00 31.92  ? 134 VAL C O   1 
ATOM 6726  C CB  . VAL C 1 134 ? -31.762 -57.490 -36.057 1.00 36.89  ? 134 VAL C CB  1 
ATOM 6727  C CG1 . VAL C 1 134 ? -32.626 -58.203 -35.024 1.00 32.26  ? 134 VAL C CG1 1 
ATOM 6728  C CG2 . VAL C 1 134 ? -32.254 -57.787 -37.466 1.00 41.70  ? 134 VAL C CG2 1 
ATOM 6729  N N   . TYR C 1 135 ? -32.419 -55.363 -33.550 1.00 34.37  ? 135 TYR C N   1 
ATOM 6730  C CA  . TYR C 1 135 ? -32.230 -55.008 -32.148 1.00 32.24  ? 135 TYR C CA  1 
ATOM 6731  C C   . TYR C 1 135 ? -32.304 -56.244 -31.260 1.00 34.46  ? 135 TYR C C   1 
ATOM 6732  O O   . TYR C 1 135 ? -33.112 -57.149 -31.491 1.00 33.08  ? 135 TYR C O   1 
ATOM 6733  C CB  . TYR C 1 135 ? -33.280 -53.981 -31.718 1.00 33.74  ? 135 TYR C CB  1 
ATOM 6734  C CG  . TYR C 1 135 ? -33.306 -53.671 -30.237 1.00 39.01  ? 135 TYR C CG  1 
ATOM 6735  C CD1 . TYR C 1 135 ? -32.193 -53.152 -29.591 1.00 44.08  ? 135 TYR C CD1 1 
ATOM 6736  C CD2 . TYR C 1 135 ? -34.461 -53.866 -29.490 1.00 45.24  ? 135 TYR C CD2 1 
ATOM 6737  C CE1 . TYR C 1 135 ? -32.221 -52.858 -28.238 1.00 45.03  ? 135 TYR C CE1 1 
ATOM 6738  C CE2 . TYR C 1 135 ? -34.501 -53.573 -28.142 1.00 51.05  ? 135 TYR C CE2 1 
ATOM 6739  C CZ  . TYR C 1 135 ? -33.382 -53.068 -27.519 1.00 45.07  ? 135 TYR C CZ  1 
ATOM 6740  O OH  . TYR C 1 135 ? -33.416 -52.776 -26.174 1.00 45.92  ? 135 TYR C OH  1 
ATOM 6741  N N   . PHE C 1 136 ? -31.449 -56.273 -30.241 1.00 35.15  ? 136 PHE C N   1 
ATOM 6742  C CA  . PHE C 1 136 ? -31.384 -57.360 -29.270 1.00 35.84  ? 136 PHE C CA  1 
ATOM 6743  C C   . PHE C 1 136 ? -31.796 -56.800 -27.913 1.00 40.88  ? 136 PHE C C   1 
ATOM 6744  O O   . PHE C 1 136 ? -31.068 -55.999 -27.319 1.00 48.18  ? 136 PHE C O   1 
ATOM 6745  C CB  . PHE C 1 136 ? -29.982 -57.963 -29.215 1.00 39.65  ? 136 PHE C CB  1 
ATOM 6746  C CG  . PHE C 1 136 ? -29.871 -59.192 -28.352 1.00 35.33  ? 136 PHE C CG  1 
ATOM 6747  C CD1 . PHE C 1 136 ? -30.998 -59.909 -27.981 1.00 37.94  ? 136 PHE C CD1 1 
ATOM 6748  C CD2 . PHE C 1 136 ? -28.634 -59.628 -27.906 1.00 35.11  ? 136 PHE C CD2 1 
ATOM 6749  C CE1 . PHE C 1 136 ? -30.891 -61.035 -27.184 1.00 34.54  ? 136 PHE C CE1 1 
ATOM 6750  C CE2 . PHE C 1 136 ? -28.522 -60.750 -27.111 1.00 47.65  ? 136 PHE C CE2 1 
ATOM 6751  C CZ  . PHE C 1 136 ? -29.651 -61.455 -26.748 1.00 41.64  ? 136 PHE C CZ  1 
ATOM 6752  N N   . LEU C 1 137 ? -32.956 -57.228 -27.421 1.00 33.90  ? 137 LEU C N   1 
ATOM 6753  C CA  . LEU C 1 137 ? -33.477 -56.796 -26.129 1.00 38.12  ? 137 LEU C CA  1 
ATOM 6754  C C   . LEU C 1 137 ? -33.162 -57.875 -25.099 1.00 40.23  ? 137 LEU C C   1 
ATOM 6755  O O   . LEU C 1 137 ? -33.651 -59.003 -25.205 1.00 42.09  ? 137 LEU C O   1 
ATOM 6756  C CB  . LEU C 1 137 ? -34.981 -56.537 -26.212 1.00 40.92  ? 137 LEU C CB  1 
ATOM 6757  C CG  . LEU C 1 137 ? -35.699 -56.091 -24.940 1.00 38.05  ? 137 LEU C CG  1 
ATOM 6758  C CD1 . LEU C 1 137 ? -35.706 -54.575 -24.817 1.00 46.68  ? 137 LEU C CD1 1 
ATOM 6759  C CD2 . LEU C 1 137 ? -37.112 -56.644 -24.914 1.00 44.43  ? 137 LEU C CD2 1 
ATOM 6760  N N   . THR C 1 138 ? -32.344 -57.528 -24.107 1.00 36.01  ? 138 THR C N   1 
ATOM 6761  C CA  . THR C 1 138 ? -31.940 -58.467 -23.068 1.00 39.92  ? 138 THR C CA  1 
ATOM 6762  C C   . THR C 1 138 ? -32.787 -58.348 -21.811 1.00 42.75  ? 138 THR C C   1 
ATOM 6763  O O   . THR C 1 138 ? -32.406 -58.883 -20.766 1.00 45.11  ? 138 THR C O   1 
ATOM 6764  C CB  . THR C 1 138 ? -30.466 -58.265 -22.713 1.00 30.32  ? 138 THR C CB  1 
ATOM 6765  O OG1 . THR C 1 138 ? -30.279 -56.954 -22.168 1.00 30.97  ? 138 THR C OG1 1 
ATOM 6766  C CG2 . THR C 1 138 ? -29.602 -58.415 -23.957 1.00 28.17  ? 138 THR C CG2 1 
ATOM 6767  N N   . THR C 1 139 ? -33.922 -57.663 -21.893 1.00 48.82  ? 139 THR C N   1 
ATOM 6768  C CA  . THR C 1 139 ? -34.808 -57.435 -20.765 1.00 41.35  ? 139 THR C CA  1 
ATOM 6769  C C   . THR C 1 139 ? -36.156 -58.090 -21.055 1.00 39.42  ? 139 THR C C   1 
ATOM 6770  O O   . THR C 1 139 ? -36.467 -58.434 -22.198 1.00 38.22  ? 139 THR C O   1 
ATOM 6771  C CB  . THR C 1 139 ? -34.967 -55.927 -20.509 1.00 50.52  ? 139 THR C CB  1 
ATOM 6772  O OG1 . THR C 1 139 ? -33.679 -55.301 -20.560 1.00 46.87  ? 139 THR C OG1 1 
ATOM 6773  C CG2 . THR C 1 139 ? -35.581 -55.658 -19.147 1.00 60.72  ? 139 THR C CG2 1 
ATOM 6774  N N   . ALA C 1 140 ? -36.939 -58.286 -19.997 1.00 44.10  ? 140 ALA C N   1 
ATOM 6775  C CA  . ALA C 1 140 ? -38.276 -58.848 -20.140 1.00 43.52  ? 140 ALA C CA  1 
ATOM 6776  C C   . ALA C 1 140 ? -39.123 -58.000 -21.081 1.00 50.70  ? 140 ALA C C   1 
ATOM 6777  O O   . ALA C 1 140 ? -38.943 -56.783 -21.192 1.00 52.79  ? 140 ALA C O   1 
ATOM 6778  C CB  . ALA C 1 140 ? -38.957 -58.947 -18.775 1.00 44.72  ? 140 ALA C CB  1 
ATOM 6779  N N   . ALA C 1 141 ? -40.061 -58.658 -21.764 1.00 47.16  ? 141 ALA C N   1 
ATOM 6780  C CA  . ALA C 1 141 ? -40.905 -57.956 -22.723 1.00 46.91  ? 141 ALA C CA  1 
ATOM 6781  C C   . ALA C 1 141 ? -41.910 -57.040 -22.034 1.00 48.54  ? 141 ALA C C   1 
ATOM 6782  O O   . ALA C 1 141 ? -42.266 -55.997 -22.590 1.00 52.98  ? 141 ALA C O   1 
ATOM 6783  C CB  . ALA C 1 141 ? -41.632 -58.957 -23.618 1.00 42.11  ? 141 ALA C CB  1 
ATOM 6784  N N   . ALA C 1 142 ? -42.372 -57.400 -20.833 1.00 43.76  ? 142 ALA C N   1 
ATOM 6785  C CA  . ALA C 1 142 ? -43.402 -56.608 -20.166 1.00 53.72  ? 142 ALA C CA  1 
ATOM 6786  C C   . ALA C 1 142 ? -42.864 -55.259 -19.706 1.00 51.39  ? 142 ALA C C   1 
ATOM 6787  O O   . ALA C 1 142 ? -43.531 -54.224 -19.863 1.00 54.97  ? 142 ALA C O   1 
ATOM 6788  C CB  . ALA C 1 142 ? -43.964 -57.384 -18.975 1.00 51.81  ? 142 ALA C CB  1 
ATOM 6789  N N   . SER C 1 143 ? -41.670 -55.258 -19.111 1.00 51.55  ? 143 SER C N   1 
ATOM 6790  C CA  . SER C 1 143 ? -41.088 -54.022 -18.603 1.00 55.84  ? 143 SER C CA  1 
ATOM 6791  C C   . SER C 1 143 ? -40.904 -53.002 -19.718 1.00 57.77  ? 143 SER C C   1 
ATOM 6792  O O   . SER C 1 143 ? -41.134 -51.805 -19.517 1.00 54.14  ? 143 SER C O   1 
ATOM 6793  C CB  . SER C 1 143 ? -39.760 -54.322 -17.914 1.00 54.01  ? 143 SER C CB  1 
ATOM 6794  O OG  . SER C 1 143 ? -39.921 -55.347 -16.946 1.00 73.53  ? 143 SER C OG  1 
ATOM 6795  N N   . SER C 1 144 ? -40.497 -53.459 -20.905 1.00 59.63  ? 144 SER C N   1 
ATOM 6796  C CA  . SER C 1 144 ? -40.383 -52.557 -22.045 1.00 60.34  ? 144 SER C CA  1 
ATOM 6797  C C   . SER C 1 144 ? -41.751 -52.205 -22.615 1.00 56.01  ? 144 SER C C   1 
ATOM 6798  O O   . SER C 1 144 ? -41.958 -51.082 -23.092 1.00 58.27  ? 144 SER C O   1 
ATOM 6799  C CB  . SER C 1 144 ? -39.509 -53.188 -23.127 1.00 53.05  ? 144 SER C CB  1 
ATOM 6800  O OG  . SER C 1 144 ? -38.281 -53.646 -22.586 1.00 60.04  ? 144 SER C OG  1 
ATOM 6801  N N   . SER C 1 145 ? -42.683 -53.166 -22.579 1.00 52.90  ? 145 SER C N   1 
ATOM 6802  C CA  . SER C 1 145 ? -44.044 -52.931 -23.051 1.00 55.18  ? 145 SER C CA  1 
ATOM 6803  C C   . SER C 1 145 ? -44.699 -51.784 -22.308 1.00 59.37  ? 145 SER C C   1 
ATOM 6804  O O   . SER C 1 145 ? -45.497 -51.048 -22.896 1.00 60.71  ? 145 SER C O   1 
ATOM 6805  C CB  . SER C 1 145 ? -44.874 -54.205 -22.896 1.00 49.42  ? 145 SER C CB  1 
ATOM 6806  O OG  . SER C 1 145 ? -44.331 -55.262 -23.666 1.00 67.26  ? 145 SER C OG  1 
ATOM 6807  N N   . ILE C 1 146 ? -44.379 -51.617 -21.025 1.00 55.63  ? 146 ILE C N   1 
ATOM 6808  C CA  . ILE C 1 146 ? -44.886 -50.493 -20.237 1.00 50.13  ? 146 ILE C CA  1 
ATOM 6809  C C   . ILE C 1 146 ? -44.672 -49.188 -21.000 1.00 52.54  ? 146 ILE C C   1 
ATOM 6810  O O   . ILE C 1 146 ? -45.632 -48.542 -21.448 1.00 57.09  ? 146 ILE C O   1 
ATOM 6811  C CB  . ILE C 1 146 ? -44.210 -50.432 -18.854 1.00 59.87  ? 146 ILE C CB  1 
ATOM 6812  C CG1 . ILE C 1 146 ? -44.412 -51.746 -18.095 1.00 62.89  ? 146 ILE C CG1 1 
ATOM 6813  C CG2 . ILE C 1 146 ? -44.753 -49.268 -18.046 1.00 50.85  ? 146 ILE C CG2 1 
ATOM 6814  C CD1 . ILE C 1 146 ? -45.856 -52.140 -17.930 1.00 58.00  ? 146 ILE C CD1 1 
ATOM 6815  N N   . GLY C 1 147 ? -43.404 -48.808 -21.177 1.00 61.26  ? 147 GLY C N   1 
ATOM 6816  C CA  . GLY C 1 147 ? -43.098 -47.554 -21.843 1.00 60.99  ? 147 GLY C CA  1 
ATOM 6817  C C   . GLY C 1 147 ? -43.482 -47.528 -23.309 1.00 57.48  ? 147 GLY C C   1 
ATOM 6818  O O   . GLY C 1 147 ? -43.899 -46.484 -23.827 1.00 59.03  ? 147 GLY C O   1 
ATOM 6819  N N   . LEU C 1 148 ? -43.356 -48.662 -24.004 1.00 51.31  ? 148 LEU C N   1 
ATOM 6820  C CA  . LEU C 1 148 ? -43.690 -48.663 -25.425 1.00 55.33  ? 148 LEU C CA  1 
ATOM 6821  C C   . LEU C 1 148 ? -45.181 -48.426 -25.636 1.00 59.88  ? 148 LEU C C   1 
ATOM 6822  O O   . LEU C 1 148 ? -45.579 -47.745 -26.590 1.00 58.13  ? 148 LEU C O   1 
ATOM 6823  C CB  . LEU C 1 148 ? -43.256 -49.972 -26.078 1.00 54.19  ? 148 LEU C CB  1 
ATOM 6824  C CG  . LEU C 1 148 ? -43.113 -49.900 -27.599 1.00 57.23  ? 148 LEU C CG  1 
ATOM 6825  C CD1 . LEU C 1 148 ? -42.198 -48.752 -28.000 1.00 64.02  ? 148 LEU C CD1 1 
ATOM 6826  C CD2 . LEU C 1 148 ? -42.589 -51.216 -28.146 1.00 49.14  ? 148 LEU C CD2 1 
ATOM 6827  N N   . HIS C 1 149 ? -46.037 -48.914 -24.737 1.00 56.45  ? 149 HIS C N   1 
ATOM 6828  C CA  . HIS C 1 149 ? -47.503 -48.664 -24.851 1.00 55.46  ? 149 HIS C CA  1 
ATOM 6829  C C   . HIS C 1 149 ? -47.804 -47.199 -24.586 1.00 53.54  ? 149 HIS C C   1 
ATOM 6830  O O   . HIS C 1 149 ? -48.627 -46.638 -25.290 1.00 46.31  ? 149 HIS C O   1 
ATOM 6831  C CB  . HIS C 1 149 ? -48.283 -49.503 -23.839 1.00 57.65  ? 149 HIS C CB  1 
ATOM 6832  C CG  . HIS C 1 149 ? -49.757 -49.297 -23.854 1.00 57.75  ? 149 HIS C CG  1 
ATOM 6833  N ND1 . HIS C 1 149 ? -50.594 -50.065 -24.628 1.00 58.86  ? 149 HIS C ND1 1 
ATOM 6834  C CD2 . HIS C 1 149 ? -50.544 -48.434 -23.184 1.00 53.86  ? 149 HIS C CD2 1 
ATOM 6835  C CE1 . HIS C 1 149 ? -51.834 -49.674 -24.447 1.00 65.81  ? 149 HIS C CE1 1 
ATOM 6836  N NE2 . HIS C 1 149 ? -51.828 -48.673 -23.573 1.00 58.56  ? 149 HIS C NE2 1 
ATOM 6837  N N   . ALA C 1 150 ? -47.125 -46.616 -23.619 1.00 56.72  ? 150 ALA C N   1 
ATOM 6838  C CA  . ALA C 1 150 ? -47.393 -45.224 -23.214 1.00 56.91  ? 150 ALA C CA  1 
ATOM 6839  C C   . ALA C 1 150 ? -47.119 -44.283 -24.377 1.00 56.93  ? 150 ALA C C   1 
ATOM 6840  O O   . ALA C 1 150 ? -47.614 -43.155 -24.350 1.00 58.46  ? 150 ALA C O   1 
ATOM 6841  C CB  . ALA C 1 150 ? -46.520 -44.885 -22.048 1.00 57.28  ? 150 ALA C CB  1 
ATOM 6842  N N   . PHE C 1 151 ? -46.355 -44.757 -25.366 1.00 61.35  ? 151 PHE C N   1 
ATOM 6843  C CA  . PHE C 1 151 ? -46.056 -43.944 -26.572 1.00 62.82  ? 151 PHE C CA  1 
ATOM 6844  C C   . PHE C 1 151 ? -46.999 -44.373 -27.698 1.00 63.09  ? 151 PHE C C   1 
ATOM 6845  O O   . PHE C 1 151 ? -47.656 -43.498 -28.296 1.00 70.86  ? 151 PHE C O   1 
ATOM 6846  C CB  . PHE C 1 151 ? -44.592 -44.126 -26.974 1.00 55.02  ? 151 PHE C CB  1 
ATOM 6847  C CG  . PHE C 1 151 ? -44.239 -43.583 -28.336 1.00 64.06  ? 151 PHE C CG  1 
ATOM 6848  C CD1 . PHE C 1 151 ? -44.373 -42.234 -28.620 1.00 74.54  ? 151 PHE C CD1 1 
ATOM 6849  C CD2 . PHE C 1 151 ? -43.777 -44.424 -29.335 1.00 79.46  ? 151 PHE C CD2 1 
ATOM 6850  C CE1 . PHE C 1 151 ? -44.049 -41.739 -29.871 1.00 79.33  ? 151 PHE C CE1 1 
ATOM 6851  C CE2 . PHE C 1 151 ? -43.456 -43.927 -30.588 1.00 78.63  ? 151 PHE C CE2 1 
ATOM 6852  C CZ  . PHE C 1 151 ? -43.592 -42.585 -30.854 1.00 67.26  ? 151 PHE C CZ  1 
ATOM 6853  N N   . LYS C 1 152 ? -46.991 -45.641 -28.050 1.00 57.63  ? 152 LYS C N   1 
ATOM 6854  C CA  . LYS C 1 152 ? -47.803 -46.007 -29.229 1.00 59.31  ? 152 LYS C CA  1 
ATOM 6855  C C   . LYS C 1 152 ? -49.262 -45.653 -28.949 1.00 58.54  ? 152 LYS C C   1 
ATOM 6856  O O   . LYS C 1 152 ? -49.894 -45.020 -29.810 1.00 72.24  ? 152 LYS C O   1 
ATOM 6857  C CB  . LYS C 1 152 ? -47.526 -47.452 -29.640 1.00 57.03  ? 152 LYS C CB  1 
ATOM 6858  C CG  . LYS C 1 152 ? -46.075 -47.753 -29.976 1.00 62.27  ? 152 LYS C CG  1 
ATOM 6859  C CD  . LYS C 1 152 ? -45.592 -47.029 -31.207 1.00 54.65  ? 152 LYS C CD  1 
ATOM 6860  C CE  . LYS C 1 152 ? -44.125 -47.266 -31.484 1.00 60.18  ? 152 LYS C CE  1 
ATOM 6861  N NZ  . LYS C 1 152 ? -43.767 -48.695 -31.340 1.00 60.54  ? 152 LYS C NZ  1 
ATOM 6862  N N   . ASN C 1 153 ? -49.767 -46.050 -27.788 1.00 64.03  ? 153 ASN C N   1 
ATOM 6863  C CA  . ASN C 1 153 ? -51.187 -45.795 -27.448 1.00 61.24  ? 153 ASN C CA  1 
ATOM 6864  C C   . ASN C 1 153 ? -51.177 -44.902 -26.214 1.00 63.50  ? 153 ASN C C   1 
ATOM 6865  O O   . ASN C 1 153 ? -51.231 -45.434 -25.100 1.00 60.32  ? 153 ASN C O   1 
ATOM 6866  C CB  . ASN C 1 153 ? -51.903 -47.130 -27.267 1.00 56.41  ? 153 ASN C CB  1 
ATOM 6867  C CG  . ASN C 1 153 ? -51.790 -48.020 -28.483 1.00 60.50  ? 153 ASN C CG  1 
ATOM 6868  O OD1 . ASN C 1 153 ? -51.809 -47.543 -29.613 1.00 63.22  ? 153 ASN C OD1 1 
ATOM 6869  N ND2 . ASN C 1 153 ? -51.681 -49.318 -28.261 1.00 63.27  ? 153 ASN C ND2 1 
ATOM 6870  N N   . PRO C 1 154 ? -51.231 -43.565 -26.353 1.00 64.07  ? 154 PRO C N   1 
ATOM 6871  C CA  . PRO C 1 154 ? -51.046 -42.692 -25.198 1.00 62.70  ? 154 PRO C CA  1 
ATOM 6872  C C   . PRO C 1 154 ? -52.018 -42.851 -24.025 1.00 75.04  ? 154 PRO C C   1 
ATOM 6873  O O   . PRO C 1 154 ? -51.552 -42.879 -22.913 1.00 86.80  ? 154 PRO C O   1 
ATOM 6874  C CB  . PRO C 1 154 ? -51.265 -41.298 -25.797 1.00 61.27  ? 154 PRO C CB  1 
ATOM 6875  C CG  . PRO C 1 154 ? -50.920 -41.461 -27.257 1.00 69.96  ? 154 PRO C CG  1 
ATOM 6876  C CD  . PRO C 1 154 ? -51.431 -42.840 -27.603 1.00 71.77  ? 154 PRO C CD  1 
ATOM 6877  N N   . GLY C 1 155 ? -53.313 -42.960 -24.289 1.00 59.01  ? 155 GLY C N   1 
ATOM 6878  C CA  . GLY C 1 155 ? -54.274 -43.010 -23.175 1.00 58.80  ? 155 GLY C CA  1 
ATOM 6879  C C   . GLY C 1 155 ? -55.141 -44.252 -23.213 1.00 69.16  ? 155 GLY C C   1 
ATOM 6880  O O   . GLY C 1 155 ? -56.301 -44.161 -22.757 1.00 72.65  ? 155 GLY C O   1 
ATOM 6881  N N   . GLU C 1 156 ? -54.641 -45.358 -23.762 1.00 76.56  ? 156 GLU C N   1 
ATOM 6882  C CA  . GLU C 1 156 ? -55.520 -46.544 -23.944 1.00 77.29  ? 156 GLU C CA  1 
ATOM 6883  C C   . GLU C 1 156 ? -55.441 -47.510 -22.758 1.00 80.64  ? 156 GLU C C   1 
ATOM 6884  O O   . GLU C 1 156 ? -56.109 -48.555 -22.850 1.00 99.53  ? 156 GLU C O   1 
ATOM 6885  C CB  . GLU C 1 156 ? -55.306 -47.192 -25.316 1.00 74.68  ? 156 GLU C CB  1 
ATOM 6886  C CG  . GLU C 1 156 ? -55.909 -46.399 -26.463 1.00 74.73  ? 156 GLU C CG  1 
ATOM 6887  C CD  . GLU C 1 156 ? -56.064 -47.164 -27.766 1.00 81.89  ? 156 GLU C CD  1 
ATOM 6888  O OE1 . GLU C 1 156 ? -55.451 -48.240 -27.896 1.00 69.37  ? 156 GLU C OE1 1 
ATOM 6889  O OE2 . GLU C 1 156 ? -56.809 -46.689 -28.648 1.00 93.95  ? 156 GLU C OE2 1 
ATOM 6890  N N   . LYS C 1 157 ? -54.597 -47.242 -21.762 1.00 72.95  ? 157 LYS C N   1 
ATOM 6891  C CA  . LYS C 1 157 ? -54.518 -48.070 -20.523 1.00 79.78  ? 157 LYS C CA  1 
ATOM 6892  C C   . LYS C 1 157 ? -53.707 -49.328 -20.824 1.00 77.20  ? 157 LYS C C   1 
ATOM 6893  O O   . LYS C 1 157 ? -53.918 -49.912 -21.885 1.00 81.52  ? 157 LYS C O   1 
ATOM 6894  C CB  . LYS C 1 157 ? -55.884 -48.417 -19.925 1.00 73.50  ? 157 LYS C CB  1 
ATOM 6895  C CG  . LYS C 1 157 ? -55.855 -49.281 -18.673 1.00 80.75  ? 157 LYS C CG  1 
ATOM 6896  C CD  . LYS C 1 157 ? -55.147 -48.635 -17.503 1.00 86.69  ? 157 LYS C CD  1 
ATOM 6897  C CE  . LYS C 1 157 ? -55.263 -49.418 -16.213 1.00 93.09  ? 157 LYS C CE  1 
ATOM 6898  N NZ  . LYS C 1 157 ? -54.382 -48.865 -15.156 1.00 92.98  ? 157 LYS C NZ  1 
ATOM 6899  N N   . TYR C 1 158 ? -52.909 -49.792 -19.874 1.00 71.73  ? 158 TYR C N   1 
ATOM 6900  C CA  . TYR C 1 158 ? -52.174 -51.053 -20.116 1.00 66.85  ? 158 TYR C CA  1 
ATOM 6901  C C   . TYR C 1 158 ? -53.200 -52.172 -20.219 1.00 64.49  ? 158 TYR C C   1 
ATOM 6902  O O   . TYR C 1 158 ? -54.159 -52.178 -19.447 1.00 63.97  ? 158 TYR C O   1 
ATOM 6903  C CB  . TYR C 1 158 ? -51.097 -51.279 -19.055 1.00 65.77  ? 158 TYR C CB  1 
ATOM 6904  C CG  . TYR C 1 158 ? -50.019 -52.253 -19.436 1.00 63.94  ? 158 TYR C CG  1 
ATOM 6905  C CD1 . TYR C 1 158 ? -49.082 -51.938 -20.406 1.00 61.86  ? 158 TYR C CD1 1 
ATOM 6906  C CD2 . TYR C 1 158 ? -49.928 -53.488 -18.822 1.00 58.92  ? 158 TYR C CD2 1 
ATOM 6907  C CE1 . TYR C 1 158 ? -48.090 -52.830 -20.765 1.00 63.66  ? 158 TYR C CE1 1 
ATOM 6908  C CE2 . TYR C 1 158 ? -48.937 -54.387 -19.163 1.00 53.46  ? 158 TYR C CE2 1 
ATOM 6909  C CZ  . TYR C 1 158 ? -48.017 -54.060 -20.140 1.00 62.38  ? 158 TYR C CZ  1 
ATOM 6910  O OH  . TYR C 1 158 ? -47.043 -54.951 -20.473 1.00 67.37  ? 158 TYR C OH  1 
ATOM 6911  N N   . PRO C 1 159 ? -52.996 -53.151 -21.117 1.00 65.20  ? 159 PRO C N   1 
ATOM 6912  C CA  . PRO C 1 159 ? -53.966 -54.213 -21.334 1.00 67.42  ? 159 PRO C CA  1 
ATOM 6913  C C   . PRO C 1 159 ? -54.218 -55.080 -20.097 1.00 66.52  ? 159 PRO C C   1 
ATOM 6914  O O   . PRO C 1 159 ? -55.150 -55.846 -20.138 1.00 69.83  ? 159 PRO C O   1 
ATOM 6915  C CB  . PRO C 1 159 ? -53.312 -55.014 -22.458 1.00 61.78  ? 159 PRO C CB  1 
ATOM 6916  C CG  . PRO C 1 159 ? -52.526 -53.992 -23.213 1.00 61.36  ? 159 PRO C CG  1 
ATOM 6917  C CD  . PRO C 1 159 ? -51.911 -53.185 -22.097 1.00 63.21  ? 159 PRO C CD  1 
ATOM 6918  N N   . PHE C 1 160 ? -53.368 -54.973 -19.070 1.00 64.13  ? 160 PHE C N   1 
ATOM 6919  C CA  . PHE C 1 160 ? -53.518 -55.796 -17.840 1.00 66.79  ? 160 PHE C CA  1 
ATOM 6920  C C   . PHE C 1 160 ? -53.418 -54.959 -16.552 1.00 67.32  ? 160 PHE C C   1 
ATOM 6921  O O   . PHE C 1 160 ? -52.252 -54.722 -16.200 1.00 63.86  ? 160 PHE C O   1 
ATOM 6922  C CB  . PHE C 1 160 ? -52.383 -56.816 -17.854 1.00 62.74  ? 160 PHE C CB  1 
ATOM 6923  C CG  . PHE C 1 160 ? -52.050 -57.322 -19.237 1.00 62.22  ? 160 PHE C CG  1 
ATOM 6924  C CD1 . PHE C 1 160 ? -52.940 -58.114 -19.941 1.00 49.06  ? 160 PHE C CD1 1 
ATOM 6925  C CD2 . PHE C 1 160 ? -50.858 -56.983 -19.851 1.00 66.29  ? 160 PHE C CD2 1 
ATOM 6926  C CE1 . PHE C 1 160 ? -52.652 -58.542 -21.226 1.00 52.96  ? 160 PHE C CE1 1 
ATOM 6927  C CE2 . PHE C 1 160 ? -50.562 -57.426 -21.131 1.00 60.58  ? 160 PHE C CE2 1 
ATOM 6928  C CZ  . PHE C 1 160 ? -51.461 -58.200 -21.819 1.00 49.58  ? 160 PHE C CZ  1 
ATOM 6929  N N   . PRO C 1 161 ? -54.492 -54.529 -15.801 1.00 61.91  ? 161 PRO C N   1 
ATOM 6930  C CA  . PRO C 1 161 ? -54.251 -53.782 -14.559 1.00 70.54  ? 161 PRO C CA  1 
ATOM 6931  C C   . PRO C 1 161 ? -53.409 -54.578 -13.549 1.00 64.39  ? 161 PRO C C   1 
ATOM 6932  O O   . PRO C 1 161 ? -52.579 -53.976 -12.894 1.00 72.48  ? 161 PRO C O   1 
ATOM 6933  C CB  . PRO C 1 161 ? -55.656 -53.514 -14.002 1.00 79.25  ? 161 PRO C CB  1 
ATOM 6934  C CG  . PRO C 1 161 ? -56.524 -54.581 -14.635 1.00 68.62  ? 161 PRO C CG  1 
ATOM 6935  C CD  . PRO C 1 161 ? -55.911 -54.837 -15.995 1.00 60.25  ? 161 PRO C CD  1 
ATOM 6936  N N   . ASP C 1 162 ? -53.653 -55.887 -13.439 1.00 58.14  ? 162 ASP C N   1 
ATOM 6937  C CA  . ASP C 1 162 ? -52.937 -56.735 -12.447 1.00 70.55  ? 162 ASP C CA  1 
ATOM 6938  C C   . ASP C 1 162 ? -51.429 -56.478 -12.519 1.00 67.22  ? 162 ASP C C   1 
ATOM 6939  O O   . ASP C 1 162 ? -50.810 -56.338 -11.446 1.00 67.50  ? 162 ASP C O   1 
ATOM 6940  C CB  . ASP C 1 162 ? -53.257 -58.216 -12.660 1.00 64.45  ? 162 ASP C CB  1 
ATOM 6941  C CG  . ASP C 1 162 ? -54.741 -58.533 -12.569 1.00 64.03  ? 162 ASP C CG  1 
ATOM 6942  O OD1 . ASP C 1 162 ? -55.509 -57.639 -12.161 1.00 62.65  ? 162 ASP C OD1 1 
ATOM 6943  O OD2 . ASP C 1 162 ? -55.117 -59.671 -12.912 1.00 58.58  ? 162 ASP C OD2 1 
ATOM 6944  N N   . PHE C 1 163 ? -50.861 -56.417 -13.728 1.00 58.89  ? 163 PHE C N   1 
ATOM 6945  C CA  . PHE C 1 163 ? -49.397 -56.256 -13.865 1.00 58.42  ? 163 PHE C CA  1 
ATOM 6946  C C   . PHE C 1 163 ? -49.080 -54.768 -13.773 1.00 66.76  ? 163 PHE C C   1 
ATOM 6947  O O   . PHE C 1 163 ? -48.260 -54.379 -12.932 1.00 72.75  ? 163 PHE C O   1 
ATOM 6948  C CB  . PHE C 1 163 ? -48.920 -56.834 -15.197 1.00 57.83  ? 163 PHE C CB  1 
ATOM 6949  C CG  . PHE C 1 163 ? -47.444 -56.680 -15.441 1.00 52.36  ? 163 PHE C CG  1 
ATOM 6950  C CD1 . PHE C 1 163 ? -46.538 -57.495 -14.785 1.00 57.96  ? 163 PHE C CD1 1 
ATOM 6951  C CD2 . PHE C 1 163 ? -46.962 -55.712 -16.304 1.00 51.85  ? 163 PHE C CD2 1 
ATOM 6952  C CE1 . PHE C 1 163 ? -45.179 -57.346 -14.994 1.00 57.27  ? 163 PHE C CE1 1 
ATOM 6953  C CE2 . PHE C 1 163 ? -45.603 -55.558 -16.503 1.00 57.40  ? 163 PHE C CE2 1 
ATOM 6954  C CZ  . PHE C 1 163 ? -44.714 -56.374 -15.845 1.00 62.59  ? 163 PHE C CZ  1 
ATOM 6955  N N   . TYR C 1 164 ? -49.713 -53.959 -14.622 1.00 63.36  ? 164 TYR C N   1 
ATOM 6956  C CA  . TYR C 1 164 ? -49.509 -52.494 -14.537 1.00 65.74  ? 164 TYR C CA  1 
ATOM 6957  C C   . TYR C 1 164 ? -50.856 -51.782 -14.524 1.00 72.77  ? 164 TYR C C   1 
ATOM 6958  O O   . TYR C 1 164 ? -51.626 -51.930 -15.479 1.00 84.08  ? 164 TYR C O   1 
ATOM 6959  C CB  . TYR C 1 164 ? -48.661 -51.975 -15.696 1.00 68.40  ? 164 TYR C CB  1 
ATOM 6960  C CG  . TYR C 1 164 ? -48.443 -50.484 -15.703 1.00 70.32  ? 164 TYR C CG  1 
ATOM 6961  C CD1 . TYR C 1 164 ? -47.913 -49.836 -14.605 1.00 71.34  ? 164 TYR C CD1 1 
ATOM 6962  C CD2 . TYR C 1 164 ? -48.767 -49.723 -16.812 1.00 67.16  ? 164 TYR C CD2 1 
ATOM 6963  C CE1 . TYR C 1 164 ? -47.715 -48.468 -14.601 1.00 73.40  ? 164 TYR C CE1 1 
ATOM 6964  C CE2 . TYR C 1 164 ? -48.571 -48.354 -16.829 1.00 76.32  ? 164 TYR C CE2 1 
ATOM 6965  C CZ  . TYR C 1 164 ? -48.045 -47.722 -15.718 1.00 79.73  ? 164 TYR C CZ  1 
ATOM 6966  O OH  . TYR C 1 164 ? -47.848 -46.374 -15.721 1.00 83.47  ? 164 TYR C OH  1 
ATOM 6967  N N   . ASP C 1 165 ? -51.112 -51.021 -13.467 1.00 72.12  ? 165 ASP C N   1 
ATOM 6968  C CA  . ASP C 1 165 ? -52.367 -50.239 -13.419 1.00 82.20  ? 165 ASP C CA  1 
ATOM 6969  C C   . ASP C 1 165 ? -52.037 -48.798 -13.798 1.00 82.82  ? 165 ASP C C   1 
ATOM 6970  O O   . ASP C 1 165 ? -51.602 -48.038 -12.918 1.00 83.40  ? 165 ASP C O   1 
ATOM 6971  C CB  . ASP C 1 165 ? -53.037 -50.341 -12.053 1.00 82.06  ? 165 ASP C CB  1 
ATOM 6972  C CG  . ASP C 1 165 ? -54.433 -49.739 -12.017 1.00 93.66  ? 165 ASP C CG  1 
ATOM 6973  O OD1 . ASP C 1 165 ? -54.864 -49.198 -13.051 1.00 95.85  ? 165 ASP C OD1 1 
ATOM 6974  O OD2 . ASP C 1 165 ? -55.084 -49.827 -10.957 1.00 101.55 ? 165 ASP C OD2 1 
ATOM 6975  N N   . ASN C 1 166 ? -52.255 -48.451 -15.065 1.00 82.35  ? 166 ASN C N   1 
ATOM 6976  C CA  . ASN C 1 166 ? -51.942 -47.089 -15.556 1.00 89.06  ? 166 ASN C CA  1 
ATOM 6977  C C   . ASN C 1 166 ? -52.712 -46.053 -14.741 1.00 99.11  ? 166 ASN C C   1 
ATOM 6978  O O   . ASN C 1 166 ? -52.063 -45.121 -14.240 1.00 97.48  ? 166 ASN C O   1 
ATOM 6979  C CB  . ASN C 1 166 ? -52.256 -46.963 -17.051 1.00 83.33  ? 166 ASN C CB  1 
ATOM 6980  C CG  . ASN C 1 166 ? -51.981 -45.581 -17.603 1.00 95.65  ? 166 ASN C CG  1 
ATOM 6981  O OD1 . ASN C 1 166 ? -52.890 -44.899 -18.070 1.00 104.76 ? 166 ASN C OD1 1 
ATOM 6982  N ND2 . ASN C 1 166 ? -50.730 -45.155 -17.547 1.00 97.20  ? 166 ASN C ND2 1 
ATOM 6983  N N   . SER C 1 167 ? -54.034 -46.221 -14.589 1.00 96.47  ? 167 SER C N   1 
ATOM 6984  C CA  . SER C 1 167 ? -54.840 -45.161 -13.927 1.00 102.40 ? 167 SER C CA  1 
ATOM 6985  C C   . SER C 1 167 ? -54.009 -44.461 -12.848 1.00 105.32 ? 167 SER C C   1 
ATOM 6986  O O   . SER C 1 167 ? -54.174 -43.234 -12.709 1.00 112.25 ? 167 SER C O   1 
ATOM 6987  C CB  . SER C 1 167 ? -56.106 -45.727 -13.351 1.00 107.06 ? 167 SER C CB  1 
ATOM 6988  O OG  . SER C 1 167 ? -56.964 -44.687 -12.907 1.00 112.19 ? 167 SER C OG  1 
ATOM 6989  N N   . ASN C 1 178 ? -37.352 -35.256 -20.565 1.00 147.70 ? 178 ASN C N   1 
ATOM 6990  C CA  . ASN C 1 178 ? -38.783 -35.096 -20.785 1.00 155.87 ? 178 ASN C CA  1 
ATOM 6991  C C   . ASN C 1 178 ? -39.174 -35.556 -22.184 1.00 147.85 ? 178 ASN C C   1 
ATOM 6992  O O   . ASN C 1 178 ? -40.340 -35.845 -22.455 1.00 145.22 ? 178 ASN C O   1 
ATOM 6993  C CB  . ASN C 1 178 ? -39.199 -33.640 -20.576 1.00 158.95 ? 178 ASN C CB  1 
ATOM 6994  C CG  . ASN C 1 178 ? -38.435 -32.679 -21.468 1.00 152.02 ? 178 ASN C CG  1 
ATOM 6995  O OD1 . ASN C 1 178 ? -38.853 -32.385 -22.587 1.00 141.77 ? 178 ASN C OD1 1 
ATOM 6996  N ND2 . ASN C 1 178 ? -37.307 -32.185 -20.972 1.00 155.26 ? 178 ASN C ND2 1 
ATOM 6997  N N   . MET C 1 179 ? -38.185 -35.628 -23.075 1.00 142.82 ? 179 MET C N   1 
ATOM 6998  C CA  . MET C 1 179 ? -38.427 -36.023 -24.456 1.00 141.62 ? 179 MET C CA  1 
ATOM 6999  C C   . MET C 1 179 ? -37.192 -36.672 -25.064 1.00 136.15 ? 179 MET C C   1 
ATOM 7000  O O   . MET C 1 179 ? -37.299 -37.625 -25.845 1.00 131.97 ? 179 MET C O   1 
ATOM 7001  C CB  . MET C 1 179 ? -38.856 -34.807 -25.283 1.00 142.85 ? 179 MET C CB  1 
ATOM 7002  C CG  . MET C 1 179 ? -38.780 -34.991 -26.799 1.00 148.20 ? 179 MET C CG  1 
ATOM 7003  S SD  . MET C 1 179 ? -39.737 -36.385 -27.431 1.00 156.05 ? 179 MET C SD  1 
ATOM 7004  C CE  . MET C 1 179 ? -41.395 -35.928 -26.935 1.00 138.61 ? 179 MET C CE  1 
ATOM 7005  N N   . LYS C 1 180 ? -36.014 -36.174 -24.696 1.00 135.80 ? 180 LYS C N   1 
ATOM 7006  C CA  . LYS C 1 180 ? -34.773 -36.524 -25.383 1.00 134.37 ? 180 LYS C CA  1 
ATOM 7007  C C   . LYS C 1 180 ? -34.317 -37.932 -25.009 1.00 123.57 ? 180 LYS C C   1 
ATOM 7008  O O   . LYS C 1 180 ? -33.259 -38.397 -25.446 1.00 123.07 ? 180 LYS C O   1 
ATOM 7009  C CB  . LYS C 1 180 ? -33.678 -35.503 -25.063 1.00 141.26 ? 180 LYS C CB  1 
ATOM 7010  C CG  . LYS C 1 180 ? -34.095 -34.060 -25.236 1.00 138.23 ? 180 LYS C CG  1 
ATOM 7011  C CD  . LYS C 1 180 ? -33.006 -33.117 -24.749 1.00 149.11 ? 180 LYS C CD  1 
ATOM 7012  C CE  . LYS C 1 180 ? -33.522 -31.693 -24.635 1.00 151.05 ? 180 LYS C CE  1 
ATOM 7013  N NZ  . LYS C 1 180 ? -34.672 -31.582 -23.699 1.00 158.02 ? 180 LYS C NZ  1 
ATOM 7014  N N   . LEU C 1 181 ? -35.114 -38.611 -24.193 1.00 119.43 ? 181 LEU C N   1 
ATOM 7015  C CA  . LEU C 1 181 ? -34.867 -39.989 -23.806 1.00 115.69 ? 181 LEU C CA  1 
ATOM 7016  C C   . LEU C 1 181 ? -35.966 -40.949 -24.242 1.00 115.84 ? 181 LEU C C   1 
ATOM 7017  O O   . LEU C 1 181 ? -35.668 -42.107 -24.560 1.00 107.11 ? 181 LEU C O   1 
ATOM 7018  C CB  . LEU C 1 181 ? -34.679 -40.080 -22.280 1.00 112.95 ? 181 LEU C CB  1 
ATOM 7019  C CG  . LEU C 1 181 ? -33.904 -41.287 -21.748 1.00 105.90 ? 181 LEU C CG  1 
ATOM 7020  C CD1 . LEU C 1 181 ? -33.148 -40.913 -20.483 1.00 105.01 ? 181 LEU C CD1 1 
ATOM 7021  C CD2 . LEU C 1 181 ? -34.847 -42.443 -21.482 1.00 107.09 ? 181 LEU C CD2 1 
ATOM 7022  N N   . LEU C 1 182 ? -37.225 -40.504 -24.264 1.00 118.97 ? 182 LEU C N   1 
ATOM 7023  C CA  . LEU C 1 182 ? -38.313 -41.363 -24.717 1.00 107.59 ? 182 LEU C CA  1 
ATOM 7024  C C   . LEU C 1 182 ? -38.131 -41.748 -26.180 1.00 103.26 ? 182 LEU C C   1 
ATOM 7025  O O   . LEU C 1 182 ? -38.315 -42.914 -26.556 1.00 100.12 ? 182 LEU C O   1 
ATOM 7026  C CB  . LEU C 1 182 ? -39.653 -40.658 -24.503 1.00 109.48 ? 182 LEU C CB  1 
ATOM 7027  C CG  . LEU C 1 182 ? -40.937 -41.275 -25.061 1.00 115.48 ? 182 LEU C CG  1 
ATOM 7028  C CD1 . LEU C 1 182 ? -41.282 -42.589 -24.368 1.00 117.14 ? 182 LEU C CD1 1 
ATOM 7029  C CD2 . LEU C 1 182 ? -42.084 -40.286 -24.925 1.00 119.22 ? 182 LEU C CD2 1 
ATOM 7030  N N   . HIS C 1 183 ? -37.764 -40.776 -27.018 1.00 105.88 ? 183 HIS C N   1 
ATOM 7031  C CA  . HIS C 1 183 ? -37.504 -41.071 -28.422 1.00 100.47 ? 183 HIS C CA  1 
ATOM 7032  C C   . HIS C 1 183 ? -36.328 -42.027 -28.576 1.00 88.92  ? 183 HIS C C   1 
ATOM 7033  O O   . HIS C 1 183 ? -36.345 -42.907 -29.442 1.00 85.01  ? 183 HIS C O   1 
ATOM 7034  C CB  . HIS C 1 183 ? -37.246 -39.781 -29.194 1.00 103.93 ? 183 HIS C CB  1 
ATOM 7035  C CG  . HIS C 1 183 ? -36.826 -40.010 -30.613 1.00 100.84 ? 183 HIS C CG  1 
ATOM 7036  N ND1 . HIS C 1 183 ? -37.408 -40.965 -31.414 1.00 95.46  ? 183 HIS C ND1 1 
ATOM 7037  C CD2 . HIS C 1 183 ? -35.872 -39.413 -31.369 1.00 92.66  ? 183 HIS C CD2 1 
ATOM 7038  C CE1 . HIS C 1 183 ? -36.839 -40.944 -32.607 1.00 95.75  ? 183 HIS C CE1 1 
ATOM 7039  N NE2 . HIS C 1 183 ? -35.902 -40.012 -32.605 1.00 91.55  ? 183 HIS C NE2 1 
ATOM 7040  N N   . ASP C 1 184 ? -35.382 -41.943 -27.654 1.00 95.05  ? 184 ASP C N   1 
ATOM 7041  C CA  . ASP C 1 184 ? -34.178 -42.789 -27.806 1.00 94.04  ? 184 ASP C CA  1 
ATOM 7042  C C   . ASP C 1 184 ? -34.485 -44.207 -27.314 1.00 85.78  ? 184 ASP C C   1 
ATOM 7043  O O   . ASP C 1 184 ? -33.674 -45.091 -27.583 1.00 83.49  ? 184 ASP C O   1 
ATOM 7044  C CB  . ASP C 1 184 ? -32.968 -42.123 -27.160 1.00 96.28  ? 184 ASP C CB  1 
ATOM 7045  C CG  . ASP C 1 184 ? -32.740 -40.720 -27.683 1.00 103.57 ? 184 ASP C CG  1 
ATOM 7046  O OD1 . ASP C 1 184 ? -33.674 -39.909 -27.583 1.00 107.45 ? 184 ASP C OD1 1 
ATOM 7047  O OD2 . ASP C 1 184 ? -31.637 -40.457 -28.192 1.00 98.22  ? 184 ASP C OD2 1 
ATOM 7048  N N   . PHE C 1 185 ? -35.622 -44.413 -26.664 1.00 78.56  ? 185 PHE C N   1 
ATOM 7049  C CA  . PHE C 1 185 ? -36.026 -45.770 -26.231 1.00 70.01  ? 185 PHE C CA  1 
ATOM 7050  C C   . PHE C 1 185 ? -36.757 -46.465 -27.371 1.00 67.17  ? 185 PHE C C   1 
ATOM 7051  O O   . PHE C 1 185 ? -36.548 -47.650 -27.592 1.00 62.83  ? 185 PHE C O   1 
ATOM 7052  C CB  . PHE C 1 185 ? -36.913 -45.643 -24.997 1.00 68.17  ? 185 PHE C CB  1 
ATOM 7053  C CG  . PHE C 1 185 ? -37.810 -46.812 -24.682 1.00 62.49  ? 185 PHE C CG  1 
ATOM 7054  C CD1 . PHE C 1 185 ? -39.030 -46.969 -25.315 1.00 73.57  ? 185 PHE C CD1 1 
ATOM 7055  C CD2 . PHE C 1 185 ? -37.469 -47.721 -23.696 1.00 64.17  ? 185 PHE C CD2 1 
ATOM 7056  C CE1 . PHE C 1 185 ? -39.861 -48.030 -25.002 1.00 64.62  ? 185 PHE C CE1 1 
ATOM 7057  C CE2 . PHE C 1 185 ? -38.300 -48.784 -23.387 1.00 62.91  ? 185 PHE C CE2 1 
ATOM 7058  C CZ  . PHE C 1 185 ? -39.494 -48.937 -24.041 1.00 57.79  ? 185 PHE C CZ  1 
ATOM 7059  N N   . ILE C 1 186 ? -37.588 -45.726 -28.080 1.00 66.71  ? 186 ILE C N   1 
ATOM 7060  C CA  . ILE C 1 186 ? -38.439 -46.314 -29.147 1.00 68.63  ? 186 ILE C CA  1 
ATOM 7061  C C   . ILE C 1 186 ? -37.566 -46.532 -30.369 1.00 61.53  ? 186 ILE C C   1 
ATOM 7062  O O   . ILE C 1 186 ? -37.825 -47.456 -31.155 1.00 54.07  ? 186 ILE C O   1 
ATOM 7063  C CB  . ILE C 1 186 ? -39.589 -45.331 -29.437 1.00 74.23  ? 186 ILE C CB  1 
ATOM 7064  C CG1 . ILE C 1 186 ? -40.371 -44.988 -28.168 1.00 74.95  ? 186 ILE C CG1 1 
ATOM 7065  C CG2 . ILE C 1 186 ? -40.496 -45.861 -30.534 1.00 74.42  ? 186 ILE C CG2 1 
ATOM 7066  C CD1 . ILE C 1 186 ? -40.617 -43.516 -28.010 1.00 83.41  ? 186 ILE C CD1 1 
ATOM 7067  N N   . ALA C 1 187 ? -36.561 -45.684 -30.493 1.00 65.58  ? 187 ALA C N   1 
ATOM 7068  C CA  . ALA C 1 187 ? -35.660 -45.773 -31.658 1.00 54.52  ? 187 ALA C CA  1 
ATOM 7069  C C   . ALA C 1 187 ? -35.244 -47.215 -31.882 1.00 57.64  ? 187 ALA C C   1 
ATOM 7070  O O   . ALA C 1 187 ? -35.460 -47.731 -32.972 1.00 63.36  ? 187 ALA C O   1 
ATOM 7071  C CB  . ALA C 1 187 ? -34.458 -44.924 -31.391 1.00 70.30  ? 187 ALA C CB  1 
ATOM 7072  N N   . CYS C 1 188 ? -34.659 -47.820 -30.862 1.00 44.93  ? 188 CYS C N   1 
ATOM 7073  C CA  . CYS C 1 188 ? -34.148 -49.166 -31.107 1.00 44.80  ? 188 CYS C CA  1 
ATOM 7074  C C   . CYS C 1 188 ? -35.253 -50.128 -31.521 1.00 46.60  ? 188 CYS C C   1 
ATOM 7075  O O   . CYS C 1 188 ? -34.976 -51.142 -32.172 1.00 54.32  ? 188 CYS C O   1 
ATOM 7076  C CB  . CYS C 1 188 ? -33.418 -49.682 -29.869 1.00 56.76  ? 188 CYS C CB  1 
ATOM 7077  S SG  . CYS C 1 188 ? -34.164 -49.174 -28.311 1.00 79.16  ? 188 CYS C SG  1 
ATOM 7078  N N   . PHE C 1 189 ? -36.503 -49.840 -31.154 1.00 44.25  ? 189 PHE C N   1 
ATOM 7079  C CA  . PHE C 1 189 ? -37.612 -50.658 -31.633 1.00 37.78  ? 189 PHE C CA  1 
ATOM 7080  C C   . PHE C 1 189 ? -38.024 -50.259 -33.044 1.00 40.41  ? 189 PHE C C   1 
ATOM 7081  O O   . PHE C 1 189 ? -38.321 -51.125 -33.876 1.00 41.59  ? 189 PHE C O   1 
ATOM 7082  C CB  . PHE C 1 189 ? -38.807 -50.545 -30.686 1.00 36.99  ? 189 PHE C CB  1 
ATOM 7083  C CG  . PHE C 1 189 ? -38.537 -51.072 -29.310 1.00 47.34  ? 189 PHE C CG  1 
ATOM 7084  C CD1 . PHE C 1 189 ? -38.707 -52.416 -29.025 1.00 42.57  ? 189 PHE C CD1 1 
ATOM 7085  C CD2 . PHE C 1 189 ? -38.113 -50.227 -28.298 1.00 54.87  ? 189 PHE C CD2 1 
ATOM 7086  C CE1 . PHE C 1 189 ? -38.460 -52.907 -27.756 1.00 35.85  ? 189 PHE C CE1 1 
ATOM 7087  C CE2 . PHE C 1 189 ? -37.863 -50.709 -27.031 1.00 56.23  ? 189 PHE C CE2 1 
ATOM 7088  C CZ  . PHE C 1 189 ? -38.036 -52.051 -26.760 1.00 52.40  ? 189 PHE C CZ  1 
ATOM 7089  N N   . GLU C 1 190 ? -38.045 -48.956 -33.328 1.00 39.89  ? 190 GLU C N   1 
ATOM 7090  C CA  . GLU C 1 190 ? -38.459 -48.482 -34.645 1.00 44.46  ? 190 GLU C CA  1 
ATOM 7091  C C   . GLU C 1 190 ? -37.426 -48.836 -35.711 1.00 46.62  ? 190 GLU C C   1 
ATOM 7092  O O   . GLU C 1 190 ? -37.770 -49.388 -36.761 1.00 43.36  ? 190 GLU C O   1 
ATOM 7093  C CB  . GLU C 1 190 ? -38.690 -46.971 -34.607 1.00 57.30  ? 190 GLU C CB  1 
ATOM 7094  C CG  . GLU C 1 190 ? -38.895 -46.340 -35.974 1.00 75.26  ? 190 GLU C CG  1 
ATOM 7095  C CD  . GLU C 1 190 ? -38.472 -44.880 -36.011 1.00 85.72  ? 190 GLU C CD  1 
ATOM 7096  O OE1 . GLU C 1 190 ? -37.926 -44.387 -35.001 1.00 78.75  ? 190 GLU C OE1 1 
ATOM 7097  O OE2 . GLU C 1 190 ? -38.679 -44.228 -37.057 1.00 81.38  ? 190 GLU C OE2 1 
ATOM 7098  N N   . ARG C 1 191 ? -36.154 -48.521 -35.457 1.00 50.13  ? 191 ARG C N   1 
ATOM 7099  C CA  . ARG C 1 191 ? -35.118 -48.725 -36.463 1.00 42.54  ? 191 ARG C CA  1 
ATOM 7100  C C   . ARG C 1 191 ? -34.739 -50.188 -36.647 1.00 39.47  ? 191 ARG C C   1 
ATOM 7101  O O   . ARG C 1 191 ? -33.930 -50.492 -37.532 1.00 53.09  ? 191 ARG C O   1 
ATOM 7102  C CB  . ARG C 1 191 ? -33.873 -47.910 -36.107 1.00 46.46  ? 191 ARG C CB  1 
ATOM 7103  C CG  . ARG C 1 191 ? -33.942 -46.470 -36.575 1.00 59.36  ? 191 ARG C CG  1 
ATOM 7104  C CD  . ARG C 1 191 ? -33.956 -46.397 -38.098 1.00 72.26  ? 191 ARG C CD  1 
ATOM 7105  N NE  . ARG C 1 191 ? -34.215 -45.049 -38.588 1.00 86.07  ? 191 ARG C NE  1 
ATOM 7106  C CZ  . ARG C 1 191 ? -33.278 -44.135 -38.805 1.00 86.10  ? 191 ARG C CZ  1 
ATOM 7107  N NH1 . ARG C 1 191 ? -31.999 -44.386 -38.569 1.00 65.85  ? 191 ARG C NH1 1 
ATOM 7108  N NH2 . ARG C 1 191 ? -33.631 -42.942 -39.273 1.00 94.15  ? 191 ARG C NH2 1 
ATOM 7109  N N   . SER C 1 192 ? -35.290 -51.098 -35.847 1.00 33.87  ? 192 SER C N   1 
ATOM 7110  C CA  . SER C 1 192 ? -34.988 -52.513 -36.017 1.00 37.42  ? 192 SER C CA  1 
ATOM 7111  C C   . SER C 1 192 ? -35.618 -53.028 -37.305 1.00 38.41  ? 192 SER C C   1 
ATOM 7112  O O   . SER C 1 192 ? -36.798 -52.784 -37.572 1.00 41.83  ? 192 SER C O   1 
ATOM 7113  C CB  . SER C 1 192 ? -35.489 -53.308 -34.815 1.00 34.03  ? 192 SER C CB  1 
ATOM 7114  O OG  . SER C 1 192 ? -35.122 -54.673 -34.922 1.00 32.58  ? 192 SER C OG  1 
ATOM 7115  N N   . CYS C 1 193 ? -34.829 -53.740 -38.106 1.00 39.21  ? 193 CYS C N   1 
ATOM 7116  C CA  . CYS C 1 193 ? -35.281 -54.204 -39.412 1.00 40.87  ? 193 CYS C CA  1 
ATOM 7117  C C   . CYS C 1 193 ? -36.127 -55.462 -39.239 1.00 47.83  ? 193 CYS C C   1 
ATOM 7118  O O   . CYS C 1 193 ? -35.622 -56.505 -38.810 1.00 52.76  ? 193 CYS C O   1 
ATOM 7119  C CB  . CYS C 1 193 ? -34.087 -54.464 -40.329 1.00 45.70  ? 193 CYS C CB  1 
ATOM 7120  S SG  . CYS C 1 193 ? -34.517 -54.867 -42.040 1.00 57.93  ? 193 CYS C SG  1 
ATOM 7121  N N   . ASP C 1 194 ? -37.421 -55.349 -39.553 1.00 52.64  ? 194 ASP C N   1 
ATOM 7122  C CA  . ASP C 1 194 ? -38.363 -56.466 -39.600 1.00 49.86  ? 194 ASP C CA  1 
ATOM 7123  C C   . ASP C 1 194 ? -38.610 -57.117 -38.239 1.00 54.74  ? 194 ASP C C   1 
ATOM 7124  O O   . ASP C 1 194 ? -39.754 -57.156 -37.774 1.00 57.39  ? 194 ASP C O   1 
ATOM 7125  C CB  . ASP C 1 194 ? -37.889 -57.521 -40.601 1.00 48.01  ? 194 ASP C CB  1 
ATOM 7126  C CG  . ASP C 1 194 ? -37.805 -56.984 -42.012 1.00 60.11  ? 194 ASP C CG  1 
ATOM 7127  O OD1 . ASP C 1 194 ? -38.668 -56.167 -42.393 1.00 73.44  ? 194 ASP C OD1 1 
ATOM 7128  O OD2 . ASP C 1 194 ? -36.872 -57.379 -42.743 1.00 72.26  ? 194 ASP C OD2 1 
ATOM 7129  N N   . ILE C 1 195 ? -37.567 -57.645 -37.601 1.00 39.58  ? 195 ILE C N   1 
ATOM 7130  C CA  . ILE C 1 195 ? -37.721 -58.418 -36.378 1.00 42.32  ? 195 ILE C CA  1 
ATOM 7131  C C   . ILE C 1 195 ? -37.002 -57.715 -35.234 1.00 37.22  ? 195 ILE C C   1 
ATOM 7132  O O   . ILE C 1 195 ? -36.299 -56.725 -35.420 1.00 39.84  ? 195 ILE C O   1 
ATOM 7133  C CB  . ILE C 1 195 ? -37.207 -59.865 -36.531 1.00 35.59  ? 195 ILE C CB  1 
ATOM 7134  C CG1 . ILE C 1 195 ? -35.679 -59.886 -36.608 1.00 45.32  ? 195 ILE C CG1 1 
ATOM 7135  C CG2 . ILE C 1 195 ? -37.826 -60.529 -37.754 1.00 40.62  ? 195 ILE C CG2 1 
ATOM 7136  C CD1 . ILE C 1 195 ? -35.082 -61.277 -36.546 1.00 40.08  ? 195 ILE C CD1 1 
ATOM 7137  N N   . ILE C 1 196 ? -37.210 -58.246 -34.029 1.00 31.59  ? 196 ILE C N   1 
ATOM 7138  C CA  . ILE C 1 196 ? -36.501 -57.821 -32.826 1.00 30.02  ? 196 ILE C CA  1 
ATOM 7139  C C   . ILE C 1 196 ? -36.191 -59.067 -32.011 1.00 34.62  ? 196 ILE C C   1 
ATOM 7140  O O   . ILE C 1 196 ? -37.111 -59.764 -31.569 1.00 36.61  ? 196 ILE C O   1 
ATOM 7141  C CB  . ILE C 1 196 ? -37.306 -56.822 -31.976 1.00 28.82  ? 196 ILE C CB  1 
ATOM 7142  C CG1 . ILE C 1 196 ? -37.449 -55.486 -32.701 1.00 25.35  ? 196 ILE C CG1 1 
ATOM 7143  C CG2 . ILE C 1 196 ? -36.637 -56.626 -30.625 1.00 31.13  ? 196 ILE C CG2 1 
ATOM 7144  C CD1 . ILE C 1 196 ? -38.118 -54.417 -31.874 1.00 24.70  ? 196 ILE C CD1 1 
ATOM 7145  N N   . LEU C 1 197 ? -34.909 -59.359 -31.822 1.00 31.22  ? 197 LEU C N   1 
ATOM 7146  C CA  . LEU C 1 197 ? -34.503 -60.485 -30.999 1.00 30.70  ? 197 LEU C CA  1 
ATOM 7147  C C   . LEU C 1 197 ? -34.641 -60.133 -29.523 1.00 34.15  ? 197 LEU C C   1 
ATOM 7148  O O   . LEU C 1 197 ? -34.340 -59.011 -29.109 1.00 34.50  ? 197 LEU C O   1 
ATOM 7149  C CB  . LEU C 1 197 ? -33.061 -60.884 -31.312 1.00 33.72  ? 197 LEU C CB  1 
ATOM 7150  C CG  . LEU C 1 197 ? -32.791 -61.456 -32.705 1.00 29.87  ? 197 LEU C CG  1 
ATOM 7151  C CD1 . LEU C 1 197 ? -31.305 -61.693 -32.903 1.00 37.71  ? 197 LEU C CD1 1 
ATOM 7152  C CD2 . LEU C 1 197 ? -33.566 -62.746 -32.893 1.00 41.52  ? 197 LEU C CD2 1 
ATOM 7153  N N   . ILE C 1 198 ? -35.101 -61.096 -28.728 1.00 32.56  ? 198 ILE C N   1 
ATOM 7154  C CA  . ILE C 1 198 ? -35.317 -60.866 -27.305 1.00 34.44  ? 198 ILE C CA  1 
ATOM 7155  C C   . ILE C 1 198 ? -34.807 -62.063 -26.512 1.00 37.34  ? 198 ILE C C   1 
ATOM 7156  O O   . ILE C 1 198 ? -35.038 -63.216 -26.884 1.00 34.68  ? 198 ILE C O   1 
ATOM 7157  C CB  . ILE C 1 198 ? -36.803 -60.582 -26.988 1.00 35.03  ? 198 ILE C CB  1 
ATOM 7158  C CG1 . ILE C 1 198 ? -37.006 -60.415 -25.478 1.00 40.61  ? 198 ILE C CG1 1 
ATOM 7159  C CG2 . ILE C 1 198 ? -37.700 -61.667 -27.554 1.00 32.55  ? 198 ILE C CG2 1 
ATOM 7160  C CD1 . ILE C 1 198 ? -38.439 -60.143 -25.076 1.00 36.80  ? 198 ILE C CD1 1 
ATOM 7161  N N   . LYS C 1 199 ? -34.093 -61.775 -25.421 1.00 40.99  ? 199 LYS C N   1 
ATOM 7162  C CA  . LYS C 1 199 ? -33.649 -62.789 -24.465 1.00 44.71  ? 199 LYS C CA  1 
ATOM 7163  C C   . LYS C 1 199 ? -34.815 -63.105 -23.536 1.00 40.26  ? 199 LYS C C   1 
ATOM 7164  O O   . LYS C 1 199 ? -34.912 -62.622 -22.403 1.00 39.23  ? 199 LYS C O   1 
ATOM 7165  C CB  . LYS C 1 199 ? -32.426 -62.312 -23.691 1.00 41.67  ? 199 LYS C CB  1 
ATOM 7166  C CG  . LYS C 1 199 ? -31.889 -63.320 -22.690 1.00 41.19  ? 199 LYS C CG  1 
ATOM 7167  C CD  . LYS C 1 199 ? -30.826 -62.699 -21.797 1.00 40.72  ? 199 LYS C CD  1 
ATOM 7168  C CE  . LYS C 1 199 ? -30.381 -63.662 -20.706 1.00 46.58  ? 199 LYS C CE  1 
ATOM 7169  N NZ  . LYS C 1 199 ? -29.426 -63.012 -19.772 1.00 47.74  ? 199 LYS C NZ  1 
ATOM 7170  N N   . SER C 1 200 ? -35.727 -63.927 -24.038 1.00 39.63  ? 200 SER C N   1 
ATOM 7171  C CA  . SER C 1 200 ? -36.897 -64.339 -23.277 1.00 39.86  ? 200 SER C CA  1 
ATOM 7172  C C   . SER C 1 200 ? -37.456 -65.594 -23.929 1.00 40.45  ? 200 SER C C   1 
ATOM 7173  O O   . SER C 1 200 ? -36.943 -66.069 -24.944 1.00 43.01  ? 200 SER C O   1 
ATOM 7174  C CB  . SER C 1 200 ? -37.936 -63.213 -23.212 1.00 38.34  ? 200 SER C CB  1 
ATOM 7175  O OG  . SER C 1 200 ? -39.031 -63.571 -22.385 1.00 46.62  ? 200 SER C OG  1 
ATOM 7176  N N   . PHE C 1 201 ? -38.511 -66.136 -23.332 1.00 44.55  ? 201 PHE C N   1 
ATOM 7177  C CA  . PHE C 1 201 ? -39.135 -67.349 -23.835 1.00 47.10  ? 201 PHE C CA  1 
ATOM 7178  C C   . PHE C 1 201 ? -40.638 -67.254 -23.633 1.00 42.35  ? 201 PHE C C   1 
ATOM 7179  O O   . PHE C 1 201 ? -41.116 -66.630 -22.681 1.00 45.18  ? 201 PHE C O   1 
ATOM 7180  C CB  . PHE C 1 201 ? -38.571 -68.609 -23.158 1.00 50.41  ? 201 PHE C CB  1 
ATOM 7181  C CG  . PHE C 1 201 ? -38.139 -68.402 -21.730 1.00 54.82  ? 201 PHE C CG  1 
ATOM 7182  C CD1 . PHE C 1 201 ? -36.881 -67.895 -21.441 1.00 51.93  ? 201 PHE C CD1 1 
ATOM 7183  C CD2 . PHE C 1 201 ? -38.978 -68.734 -20.683 1.00 53.50  ? 201 PHE C CD2 1 
ATOM 7184  C CE1 . PHE C 1 201 ? -36.478 -67.705 -20.131 1.00 61.50  ? 201 PHE C CE1 1 
ATOM 7185  C CE2 . PHE C 1 201 ? -38.577 -68.553 -19.371 1.00 53.58  ? 201 PHE C CE2 1 
ATOM 7186  C CZ  . PHE C 1 201 ? -37.327 -68.034 -19.097 1.00 56.58  ? 201 PHE C CZ  1 
ATOM 7187  N N   . ARG C 1 202 ? -41.381 -67.881 -24.549 1.00 51.75  ? 202 ARG C N   1 
ATOM 7188  C CA  . ARG C 1 202 ? -42.833 -67.747 -24.554 1.00 54.04  ? 202 ARG C CA  1 
ATOM 7189  C C   . ARG C 1 202 ? -43.458 -68.320 -23.288 1.00 57.91  ? 202 ARG C C   1 
ATOM 7190  O O   . ARG C 1 202 ? -44.469 -67.795 -22.808 1.00 63.29  ? 202 ARG C O   1 
ATOM 7191  C CB  . ARG C 1 202 ? -43.413 -68.423 -25.796 1.00 55.26  ? 202 ARG C CB  1 
ATOM 7192  C CG  . ARG C 1 202 ? -44.801 -67.950 -26.188 1.00 57.37  ? 202 ARG C CG  1 
ATOM 7193  C CD  . ARG C 1 202 ? -44.900 -67.765 -27.693 1.00 65.11  ? 202 ARG C CD  1 
ATOM 7194  N NE  . ARG C 1 202 ? -44.067 -66.664 -28.161 1.00 69.35  ? 202 ARG C NE  1 
ATOM 7195  C CZ  . ARG C 1 202 ? -43.759 -66.440 -29.435 1.00 73.53  ? 202 ARG C CZ  1 
ATOM 7196  N NH1 . ARG C 1 202 ? -44.183 -67.244 -30.398 1.00 84.03  ? 202 ARG C NH1 1 
ATOM 7197  N NH2 . ARG C 1 202 ? -43.007 -65.389 -29.746 1.00 55.28  ? 202 ARG C NH2 1 
ATOM 7198  N N   . GLU C 1 203 ? -42.861 -69.370 -22.718 1.00 55.52  ? 203 GLU C N   1 
ATOM 7199  C CA  . GLU C 1 203 ? -43.438 -70.026 -21.550 1.00 59.33  ? 203 GLU C CA  1 
ATOM 7200  C C   . GLU C 1 203 ? -43.531 -69.104 -20.340 1.00 54.47  ? 203 GLU C C   1 
ATOM 7201  O O   . GLU C 1 203 ? -44.279 -69.405 -19.407 1.00 49.63  ? 203 GLU C O   1 
ATOM 7202  C CB  . GLU C 1 203 ? -42.614 -71.260 -21.186 1.00 65.06  ? 203 GLU C CB  1 
ATOM 7203  C CG  . GLU C 1 203 ? -42.206 -72.096 -22.383 1.00 73.00  ? 203 GLU C CG  1 
ATOM 7204  C CD  . GLU C 1 203 ? -43.401 -72.657 -23.130 1.00 93.02  ? 203 GLU C CD  1 
ATOM 7205  O OE1 . GLU C 1 203 ? -44.387 -73.049 -22.469 1.00 96.19  ? 203 GLU C OE1 1 
ATOM 7206  O OE2 . GLU C 1 203 ? -43.353 -72.700 -24.379 1.00 93.70  ? 203 GLU C OE2 1 
ATOM 7207  N N   . LEU C 1 204 ? -42.788 -67.998 -20.329 1.00 56.82  ? 204 LEU C N   1 
ATOM 7208  C CA  . LEU C 1 204 ? -42.801 -67.075 -19.199 1.00 59.29  ? 204 LEU C CA  1 
ATOM 7209  C C   . LEU C 1 204 ? -43.613 -65.814 -19.459 1.00 60.15  ? 204 LEU C C   1 
ATOM 7210  O O   . LEU C 1 204 ? -44.250 -65.301 -18.533 1.00 63.36  ? 204 LEU C O   1 
ATOM 7211  C CB  . LEU C 1 204 ? -41.370 -66.683 -18.817 1.00 52.36  ? 204 LEU C CB  1 
ATOM 7212  C CG  . LEU C 1 204 ? -41.180 -65.729 -17.636 1.00 40.35  ? 204 LEU C CG  1 
ATOM 7213  C CD1 . LEU C 1 204 ? -41.908 -66.229 -16.397 1.00 55.37  ? 204 LEU C CD1 1 
ATOM 7214  C CD2 . LEU C 1 204 ? -39.696 -65.534 -17.341 1.00 38.68  ? 204 LEU C CD2 1 
ATOM 7215  N N   . GLU C 1 205 ? -43.618 -65.306 -20.687 1.00 49.81  ? 205 GLU C N   1 
ATOM 7216  C CA  . GLU C 1 205 ? -44.286 -64.044 -20.979 1.00 50.22  ? 205 GLU C CA  1 
ATOM 7217  C C   . GLU C 1 205 ? -44.682 -63.985 -22.451 1.00 45.84  ? 205 GLU C C   1 
ATOM 7218  O O   . GLU C 1 205 ? -44.420 -63.003 -23.146 1.00 43.09  ? 205 GLU C O   1 
ATOM 7219  C CB  . GLU C 1 205 ? -43.399 -62.858 -20.596 1.00 46.44  ? 205 GLU C CB  1 
ATOM 7220  C CG  . GLU C 1 205 ? -41.988 -62.920 -21.177 1.00 44.48  ? 205 GLU C CG  1 
ATOM 7221  C CD  . GLU C 1 205 ? -41.265 -61.581 -21.134 1.00 52.86  ? 205 GLU C CD  1 
ATOM 7222  O OE1 . GLU C 1 205 ? -41.913 -60.556 -20.838 1.00 62.89  ? 205 GLU C OE1 1 
ATOM 7223  O OE2 . GLU C 1 205 ? -40.044 -61.556 -21.403 1.00 43.56  ? 205 GLU C OE2 1 
ATOM 7224  N N   . GLY C 1 206 ? -45.322 -65.043 -22.951 1.00 44.80  ? 206 GLY C N   1 
ATOM 7225  C CA  . GLY C 1 206 ? -45.784 -65.020 -24.330 1.00 44.43  ? 206 GLY C CA  1 
ATOM 7226  C C   . GLY C 1 206 ? -46.808 -63.929 -24.573 1.00 39.27  ? 206 GLY C C   1 
ATOM 7227  O O   . GLY C 1 206 ? -46.822 -63.302 -25.637 1.00 31.91  ? 206 GLY C O   1 
ATOM 7228  N N   . LYS C 1 207 ? -47.664 -63.679 -23.582 1.00 38.57  ? 207 LYS C N   1 
ATOM 7229  C CA  . LYS C 1 207 ? -48.644 -62.601 -23.683 1.00 42.95  ? 207 LYS C CA  1 
ATOM 7230  C C   . LYS C 1 207 ? -47.958 -61.254 -23.889 1.00 44.40  ? 207 LYS C C   1 
ATOM 7231  O O   . LYS C 1 207 ? -48.295 -60.503 -24.815 1.00 42.04  ? 207 LYS C O   1 
ATOM 7232  C CB  . LYS C 1 207 ? -49.515 -62.587 -22.425 1.00 36.52  ? 207 LYS C CB  1 
ATOM 7233  C CG  . LYS C 1 207 ? -50.375 -61.352 -22.248 1.00 57.02  ? 207 LYS C CG  1 
ATOM 7234  C CD  . LYS C 1 207 ? -51.262 -61.488 -21.014 1.00 57.15  ? 207 LYS C CD  1 
ATOM 7235  C CE  . LYS C 1 207 ? -50.443 -61.822 -19.773 1.00 49.42  ? 207 LYS C CE  1 
ATOM 7236  N NZ  . LYS C 1 207 ? -51.307 -62.070 -18.582 1.00 47.29  ? 207 LYS C NZ  1 
ATOM 7237  N N   . TYR C 1 208 ? -46.974 -60.941 -23.048 1.00 38.58  ? 208 TYR C N   1 
ATOM 7238  C CA  . TYR C 1 208 ? -46.289 -59.659 -23.164 1.00 35.51  ? 208 TYR C CA  1 
ATOM 7239  C C   . TYR C 1 208 ? -45.412 -59.601 -24.407 1.00 33.59  ? 208 TYR C C   1 
ATOM 7240  O O   . TYR C 1 208 ? -45.219 -58.519 -24.971 1.00 33.04  ? 208 TYR C O   1 
ATOM 7241  C CB  . TYR C 1 208 ? -45.471 -59.394 -21.901 1.00 41.43  ? 208 TYR C CB  1 
ATOM 7242  C CG  . TYR C 1 208 ? -46.299 -59.462 -20.638 1.00 38.41  ? 208 TYR C CG  1 
ATOM 7243  C CD1 . TYR C 1 208 ? -47.024 -58.361 -20.201 1.00 43.97  ? 208 TYR C CD1 1 
ATOM 7244  C CD2 . TYR C 1 208 ? -46.366 -60.628 -19.890 1.00 46.68  ? 208 TYR C CD2 1 
ATOM 7245  C CE1 . TYR C 1 208 ? -47.785 -58.418 -19.051 1.00 49.38  ? 208 TYR C CE1 1 
ATOM 7246  C CE2 . TYR C 1 208 ? -47.126 -60.698 -18.741 1.00 42.42  ? 208 TYR C CE2 1 
ATOM 7247  C CZ  . TYR C 1 208 ? -47.836 -59.591 -18.325 1.00 52.47  ? 208 TYR C CZ  1 
ATOM 7248  O OH  . TYR C 1 208 ? -48.596 -59.654 -17.178 1.00 70.70  ? 208 TYR C OH  1 
ATOM 7249  N N   . ILE C 1 209 ? -44.893 -60.741 -24.865 1.00 30.48  ? 209 ILE C N   1 
ATOM 7250  C CA  . ILE C 1 209 ? -44.109 -60.745 -26.097 1.00 34.81  ? 209 ILE C CA  1 
ATOM 7251  C C   . ILE C 1 209 ? -45.000 -60.431 -27.292 1.00 38.06  ? 209 ILE C C   1 
ATOM 7252  O O   . ILE C 1 209 ? -44.622 -59.657 -28.179 1.00 30.63  ? 209 ILE C O   1 
ATOM 7253  C CB  . ILE C 1 209 ? -43.378 -62.089 -26.265 1.00 33.91  ? 209 ILE C CB  1 
ATOM 7254  C CG1 . ILE C 1 209 ? -42.185 -62.166 -25.313 1.00 37.09  ? 209 ILE C CG1 1 
ATOM 7255  C CG2 . ILE C 1 209 ? -42.913 -62.279 -27.700 1.00 32.19  ? 209 ILE C CG2 1 
ATOM 7256  C CD1 . ILE C 1 209 ? -41.410 -63.459 -25.409 1.00 42.24  ? 209 ILE C CD1 1 
ATOM 7257  N N   . ASP C 1 210 ? -46.198 -61.014 -27.335 1.00 44.77  ? 210 ASP C N   1 
ATOM 7258  C CA  . ASP C 1 210 ? -47.143 -60.679 -28.396 1.00 44.03  ? 210 ASP C CA  1 
ATOM 7259  C C   . ASP C 1 210 ? -47.568 -59.216 -28.314 1.00 42.53  ? 210 ASP C C   1 
ATOM 7260  O O   . ASP C 1 210 ? -47.701 -58.541 -29.346 1.00 50.26  ? 210 ASP C O   1 
ATOM 7261  C CB  . ASP C 1 210 ? -48.358 -61.603 -28.323 1.00 60.45  ? 210 ASP C CB  1 
ATOM 7262  C CG  . ASP C 1 210 ? -47.994 -63.059 -28.551 1.00 67.61  ? 210 ASP C CG  1 
ATOM 7263  O OD1 . ASP C 1 210 ? -47.053 -63.316 -29.336 1.00 58.20  ? 210 ASP C OD1 1 
ATOM 7264  O OD2 . ASP C 1 210 ? -48.638 -63.945 -27.946 1.00 76.61  ? 210 ASP C OD2 1 
ATOM 7265  N N   . LEU C 1 211 ? -47.789 -58.713 -27.095 1.00 35.46  ? 211 LEU C N   1 
ATOM 7266  C CA  . LEU C 1 211 ? -48.104 -57.297 -26.940 1.00 41.20  ? 211 LEU C CA  1 
ATOM 7267  C C   . LEU C 1 211 ? -46.992 -56.422 -27.505 1.00 47.31  ? 211 LEU C C   1 
ATOM 7268  O O   . LEU C 1 211 ? -47.259 -55.461 -28.235 1.00 39.58  ? 211 LEU C O   1 
ATOM 7269  C CB  . LEU C 1 211 ? -48.350 -56.965 -25.469 1.00 37.85  ? 211 LEU C CB  1 
ATOM 7270  C CG  . LEU C 1 211 ? -48.604 -55.491 -25.143 1.00 45.33  ? 211 LEU C CG  1 
ATOM 7271  C CD1 . LEU C 1 211 ? -49.812 -54.967 -25.901 1.00 43.30  ? 211 LEU C CD1 1 
ATOM 7272  C CD2 . LEU C 1 211 ? -48.777 -55.299 -23.647 1.00 48.16  ? 211 LEU C CD2 1 
ATOM 7273  N N   . LEU C 1 212 ? -45.738 -56.751 -27.181 1.00 49.17  ? 212 LEU C N   1 
ATOM 7274  C CA  . LEU C 1 212 ? -44.601 -55.983 -27.684 1.00 47.18  ? 212 LEU C CA  1 
ATOM 7275  C C   . LEU C 1 212 ? -44.497 -56.079 -29.201 1.00 44.48  ? 212 LEU C C   1 
ATOM 7276  O O   . LEU C 1 212 ? -44.149 -55.099 -29.872 1.00 41.35  ? 212 LEU C O   1 
ATOM 7277  C CB  . LEU C 1 212 ? -43.317 -56.480 -27.026 1.00 40.10  ? 212 LEU C CB  1 
ATOM 7278  C CG  . LEU C 1 212 ? -42.071 -55.597 -27.106 1.00 40.15  ? 212 LEU C CG  1 
ATOM 7279  C CD1 . LEU C 1 212 ? -42.273 -54.336 -26.287 1.00 46.78  ? 212 LEU C CD1 1 
ATOM 7280  C CD2 . LEU C 1 212 ? -40.842 -56.358 -26.629 1.00 44.32  ? 212 LEU C CD2 1 
ATOM 7281  N N   . SER C 1 213 ? -44.785 -57.260 -29.756 1.00 43.53  ? 213 SER C N   1 
ATOM 7282  C CA  . SER C 1 213 ? -44.820 -57.430 -31.206 1.00 41.47  ? 213 SER C CA  1 
ATOM 7283  C C   . SER C 1 213 ? -45.807 -56.464 -31.843 1.00 44.03  ? 213 SER C C   1 
ATOM 7284  O O   . SER C 1 213 ? -45.477 -55.761 -32.805 1.00 50.47  ? 213 SER C O   1 
ATOM 7285  C CB  . SER C 1 213 ? -45.195 -58.868 -31.566 1.00 29.80  ? 213 SER C CB  1 
ATOM 7286  O OG  . SER C 1 213 ? -44.197 -59.787 -31.172 1.00 54.20  ? 213 SER C OG  1 
ATOM 7287  N N   . THR C 1 214 ? -47.035 -56.425 -31.326 1.00 40.93  ? 214 THR C N   1 
ATOM 7288  C CA  . THR C 1 214 ? -48.029 -55.545 -31.924 1.00 38.93  ? 214 THR C CA  1 
ATOM 7289  C C   . THR C 1 214 ? -47.691 -54.077 -31.698 1.00 40.52  ? 214 THR C C   1 
ATOM 7290  O O   . THR C 1 214 ? -47.931 -53.244 -32.580 1.00 48.72  ? 214 THR C O   1 
ATOM 7291  C CB  . THR C 1 214 ? -49.423 -55.855 -31.381 1.00 43.36  ? 214 THR C CB  1 
ATOM 7292  O OG1 . THR C 1 214 ? -49.468 -55.562 -29.980 1.00 50.54  ? 214 THR C OG1 1 
ATOM 7293  C CG2 . THR C 1 214 ? -49.764 -57.319 -31.608 1.00 36.33  ? 214 THR C CG2 1 
ATOM 7294  N N   . LEU C 1 215 ? -47.119 -53.740 -30.542 1.00 42.73  ? 215 LEU C N   1 
ATOM 7295  C CA  . LEU C 1 215 ? -46.835 -52.340 -30.249 1.00 40.12  ? 215 LEU C CA  1 
ATOM 7296  C C   . LEU C 1 215 ? -45.682 -51.815 -31.097 1.00 48.74  ? 215 LEU C C   1 
ATOM 7297  O O   . LEU C 1 215 ? -45.699 -50.658 -31.526 1.00 54.22  ? 215 LEU C O   1 
ATOM 7298  C CB  . LEU C 1 215 ? -46.533 -52.162 -28.759 1.00 44.84  ? 215 LEU C CB  1 
ATOM 7299  C CG  . LEU C 1 215 ? -47.740 -52.243 -27.820 1.00 50.58  ? 215 LEU C CG  1 
ATOM 7300  C CD1 . LEU C 1 215 ? -47.290 -52.180 -26.376 1.00 54.90  ? 215 LEU C CD1 1 
ATOM 7301  C CD2 . LEU C 1 215 ? -48.740 -51.133 -28.126 1.00 54.89  ? 215 LEU C CD2 1 
ATOM 7302  N N   . SER C 1 216 ? -44.675 -52.649 -31.357 1.00 50.27  ? 216 SER C N   1 
ATOM 7303  C CA  . SER C 1 216 ? -43.520 -52.213 -32.128 1.00 43.43  ? 216 SER C CA  1 
ATOM 7304  C C   . SER C 1 216 ? -43.706 -52.368 -33.631 1.00 48.07  ? 216 SER C C   1 
ATOM 7305  O O   . SER C 1 216 ? -42.898 -51.822 -34.392 1.00 50.91  ? 216 SER C O   1 
ATOM 7306  C CB  . SER C 1 216 ? -42.273 -52.987 -31.694 1.00 42.24  ? 216 SER C CB  1 
ATOM 7307  O OG  . SER C 1 216 ? -42.419 -54.374 -31.937 1.00 34.22  ? 216 SER C OG  1 
ATOM 7308  N N   . ASP C 1 217 ? -44.748 -53.076 -34.072 1.00 48.05  ? 217 ASP C N   1 
ATOM 7309  C CA  . ASP C 1 217 ? -44.928 -53.485 -35.464 1.00 47.30  ? 217 ASP C CA  1 
ATOM 7310  C C   . ASP C 1 217 ? -43.766 -54.333 -35.967 1.00 44.46  ? 217 ASP C C   1 
ATOM 7311  O O   . ASP C 1 217 ? -43.500 -54.383 -37.172 1.00 60.42  ? 217 ASP C O   1 
ATOM 7312  C CB  . ASP C 1 217 ? -45.144 -52.278 -36.389 1.00 50.90  ? 217 ASP C CB  1 
ATOM 7313  C CG  . ASP C 1 217 ? -46.445 -51.553 -36.107 1.00 67.89  ? 217 ASP C CG  1 
ATOM 7314  O OD1 . ASP C 1 217 ? -47.133 -51.927 -35.133 1.00 67.26  ? 217 ASP C OD1 1 
ATOM 7315  O OD2 . ASP C 1 217 ? -46.782 -50.615 -36.862 1.00 64.66  ? 217 ASP C OD2 1 
ATOM 7316  N N   . LYS C 1 218 ? -43.061 -55.005 -35.062 1.00 43.80  ? 218 LYS C N   1 
ATOM 7317  C CA  . LYS C 1 218 ? -41.967 -55.894 -35.414 1.00 46.59  ? 218 LYS C CA  1 
ATOM 7318  C C   . LYS C 1 218 ? -42.254 -57.287 -34.871 1.00 39.39  ? 218 LYS C C   1 
ATOM 7319  O O   . LYS C 1 218 ? -42.983 -57.450 -33.891 1.00 40.66  ? 218 LYS C O   1 
ATOM 7320  C CB  . LYS C 1 218 ? -40.623 -55.392 -34.864 1.00 39.60  ? 218 LYS C CB  1 
ATOM 7321  C CG  . LYS C 1 218 ? -39.864 -54.451 -35.793 1.00 40.62  ? 218 LYS C CG  1 
ATOM 7322  C CD  . LYS C 1 218 ? -40.588 -53.130 -35.967 1.00 45.31  ? 218 LYS C CD  1 
ATOM 7323  C CE  . LYS C 1 218 ? -39.752 -52.144 -36.750 1.00 34.47  ? 218 LYS C CE  1 
ATOM 7324  N NZ  . LYS C 1 218 ? -39.331 -52.734 -38.043 1.00 46.40  ? 218 LYS C NZ  1 
ATOM 7325  N N   . THR C 1 219 ? -41.679 -58.291 -35.520 1.00 37.90  ? 219 THR C N   1 
ATOM 7326  C CA  . THR C 1 219 ? -41.843 -59.662 -35.062 1.00 38.07  ? 219 THR C CA  1 
ATOM 7327  C C   . THR C 1 219 ? -40.837 -59.929 -33.951 1.00 49.51  ? 219 THR C C   1 
ATOM 7328  O O   . THR C 1 219 ? -39.622 -59.865 -34.172 1.00 43.56  ? 219 THR C O   1 
ATOM 7329  C CB  . THR C 1 219 ? -41.668 -60.646 -36.218 1.00 45.84  ? 219 THR C CB  1 
ATOM 7330  O OG1 . THR C 1 219 ? -42.574 -60.302 -37.273 1.00 55.61  ? 219 THR C OG1 1 
ATOM 7331  C CG2 . THR C 1 219 ? -41.972 -62.065 -35.753 1.00 43.04  ? 219 THR C CG2 1 
ATOM 7332  N N   . LEU C 1 220 ? -41.337 -60.182 -32.747 1.00 45.57  ? 220 LEU C N   1 
ATOM 7333  C CA  . LEU C 1 220 ? -40.474 -60.507 -31.623 1.00 36.25  ? 220 LEU C CA  1 
ATOM 7334  C C   . LEU C 1 220 ? -40.009 -61.949 -31.764 1.00 37.84  ? 220 LEU C C   1 
ATOM 7335  O O   . LEU C 1 220 ? -40.830 -62.873 -31.784 1.00 43.52  ? 220 LEU C O   1 
ATOM 7336  C CB  . LEU C 1 220 ? -41.203 -60.295 -30.300 1.00 35.74  ? 220 LEU C CB  1 
ATOM 7337  C CG  . LEU C 1 220 ? -40.953 -58.969 -29.579 1.00 38.67  ? 220 LEU C CG  1 
ATOM 7338  C CD1 . LEU C 1 220 ? -39.511 -58.884 -29.104 1.00 36.19  ? 220 LEU C CD1 1 
ATOM 7339  C CD2 . LEU C 1 220 ? -41.289 -57.784 -30.470 1.00 36.60  ? 220 LEU C CD2 1 
ATOM 7340  N N   . VAL C 1 221 ? -38.703 -62.140 -31.880 1.00 38.24  ? 221 VAL C N   1 
ATOM 7341  C CA  . VAL C 1 221 ? -38.115 -63.466 -32.005 1.00 41.53  ? 221 VAL C CA  1 
ATOM 7342  C C   . VAL C 1 221 ? -37.407 -63.783 -30.690 1.00 40.81  ? 221 VAL C C   1 
ATOM 7343  O O   . VAL C 1 221 ? -36.390 -63.150 -30.359 1.00 39.04  ? 221 VAL C O   1 
ATOM 7344  C CB  . VAL C 1 221 ? -37.156 -63.553 -33.198 1.00 40.27  ? 221 VAL C CB  1 
ATOM 7345  C CG1 . VAL C 1 221 ? -36.717 -64.985 -33.406 1.00 44.46  ? 221 VAL C CG1 1 
ATOM 7346  C CG2 . VAL C 1 221 ? -37.830 -63.017 -34.450 1.00 44.25  ? 221 VAL C CG2 1 
ATOM 7347  N N   . PRO C 1 222 ? -37.924 -64.710 -29.891 1.00 41.76  ? 222 PRO C N   1 
ATOM 7348  C CA  . PRO C 1 222 ? -37.259 -65.060 -28.635 1.00 44.99  ? 222 PRO C CA  1 
ATOM 7349  C C   . PRO C 1 222 ? -36.150 -66.075 -28.855 1.00 40.85  ? 222 PRO C C   1 
ATOM 7350  O O   . PRO C 1 222 ? -36.303 -67.048 -29.599 1.00 44.37  ? 222 PRO C O   1 
ATOM 7351  C CB  . PRO C 1 222 ? -38.397 -65.652 -27.794 1.00 40.19  ? 222 PRO C CB  1 
ATOM 7352  C CG  . PRO C 1 222 ? -39.327 -66.239 -28.809 1.00 52.16  ? 222 PRO C CG  1 
ATOM 7353  C CD  . PRO C 1 222 ? -39.247 -65.347 -30.019 1.00 35.43  ? 222 PRO C CD  1 
ATOM 7354  N N   . VAL C 1 223 ? -35.020 -65.837 -28.197 1.00 39.33  ? 223 VAL C N   1 
ATOM 7355  C CA  . VAL C 1 223 ? -33.876 -66.734 -28.252 1.00 38.68  ? 223 VAL C CA  1 
ATOM 7356  C C   . VAL C 1 223 ? -33.728 -67.520 -26.953 1.00 40.74  ? 223 VAL C C   1 
ATOM 7357  O O   . VAL C 1 223 ? -32.667 -68.083 -26.684 1.00 37.44  ? 223 VAL C O   1 
ATOM 7358  C CB  . VAL C 1 223 ? -32.583 -65.973 -28.591 1.00 35.26  ? 223 VAL C CB  1 
ATOM 7359  C CG1 . VAL C 1 223 ? -32.688 -65.336 -29.971 1.00 31.38  ? 223 VAL C CG1 1 
ATOM 7360  C CG2 . VAL C 1 223 ? -32.296 -64.930 -27.530 1.00 39.77  ? 223 VAL C CG2 1 
ATOM 7361  N N   . GLY C 1 224 ? -34.780 -67.563 -26.138 1.00 45.87  ? 224 GLY C N   1 
ATOM 7362  C CA  . GLY C 1 224 ? -34.760 -68.302 -24.898 1.00 46.16  ? 224 GLY C CA  1 
ATOM 7363  C C   . GLY C 1 224 ? -33.775 -67.725 -23.906 1.00 46.71  ? 224 GLY C C   1 
ATOM 7364  O O   . GLY C 1 224 ? -33.308 -66.591 -24.043 1.00 44.94  ? 224 GLY C O   1 
ATOM 7365  N N   . PRO C 1 225 ? -33.451 -68.492 -22.872 1.00 40.00  ? 225 PRO C N   1 
ATOM 7366  C CA  . PRO C 1 225 ? -32.409 -68.071 -21.938 1.00 44.50  ? 225 PRO C CA  1 
ATOM 7367  C C   . PRO C 1 225 ? -31.028 -68.418 -22.472 1.00 64.57  ? 225 PRO C C   1 
ATOM 7368  O O   . PRO C 1 225 ? -30.863 -69.243 -23.375 1.00 73.12  ? 225 PRO C O   1 
ATOM 7369  C CB  . PRO C 1 225 ? -32.729 -68.873 -20.677 1.00 46.51  ? 225 PRO C CB  1 
ATOM 7370  C CG  . PRO C 1 225 ? -33.283 -70.145 -21.216 1.00 45.93  ? 225 PRO C CG  1 
ATOM 7371  C CD  . PRO C 1 225 ? -34.059 -69.772 -22.468 1.00 43.03  ? 225 PRO C CD  1 
ATOM 7372  N N   . LEU C 1 226 ? -30.025 -67.768 -21.892 1.00 54.26  ? 226 LEU C N   1 
ATOM 7373  C CA  . LEU C 1 226 ? -28.631 -67.974 -22.267 1.00 51.78  ? 226 LEU C CA  1 
ATOM 7374  C C   . LEU C 1 226 ? -27.850 -68.286 -20.998 1.00 60.76  ? 226 LEU C C   1 
ATOM 7375  O O   . LEU C 1 226 ? -27.617 -67.391 -20.179 1.00 62.04  ? 226 LEU C O   1 
ATOM 7376  C CB  . LEU C 1 226 ? -28.072 -66.747 -22.983 1.00 60.03  ? 226 LEU C CB  1 
ATOM 7377  C CG  . LEU C 1 226 ? -28.809 -66.368 -24.272 1.00 52.61  ? 226 LEU C CG  1 
ATOM 7378  C CD1 . LEU C 1 226 ? -28.873 -64.857 -24.438 1.00 53.40  ? 226 LEU C CD1 1 
ATOM 7379  C CD2 . LEU C 1 226 ? -28.136 -67.009 -25.479 1.00 56.32  ? 226 LEU C CD2 1 
ATOM 7380  N N   . VAL C 1 227 ? -27.447 -69.550 -20.853 1.00 65.25  ? 227 VAL C N   1 
ATOM 7381  C CA  . VAL C 1 227 ? -26.850 -70.110 -19.633 1.00 59.53  ? 227 VAL C CA  1 
ATOM 7382  C C   . VAL C 1 227 ? -27.524 -69.571 -18.378 1.00 64.40  ? 227 VAL C C   1 
ATOM 7383  O O   . VAL C 1 227 ? -28.727 -69.753 -18.191 1.00 59.85  ? 227 VAL C O   1 
ATOM 7384  C CB  . VAL C 1 227 ? -25.316 -69.873 -19.579 1.00 55.63  ? 227 VAL C CB  1 
ATOM 7385  C CG1 . VAL C 1 227 ? -24.669 -70.233 -20.908 1.00 67.18  ? 227 VAL C CG1 1 
ATOM 7386  C CG2 . VAL C 1 227 ? -24.968 -68.448 -19.149 1.00 52.50  ? 227 VAL C CG2 1 
ATOM 7387  N N   . ASP C 1 236 ? -11.051 -69.280 -8.095  1.00 163.36 ? 236 ASP C N   1 
ATOM 7388  C CA  . ASP C 1 236 ? -11.685 -70.413 -8.765  1.00 173.59 ? 236 ASP C CA  1 
ATOM 7389  C C   . ASP C 1 236 ? -11.441 -71.759 -8.063  1.00 168.62 ? 236 ASP C C   1 
ATOM 7390  O O   . ASP C 1 236 ? -12.314 -72.623 -8.092  1.00 158.43 ? 236 ASP C O   1 
ATOM 7391  C CB  . ASP C 1 236 ? -11.226 -70.487 -10.225 1.00 174.23 ? 236 ASP C CB  1 
ATOM 7392  C CG  . ASP C 1 236 ? -11.777 -69.351 -11.062 1.00 169.05 ? 236 ASP C CG  1 
ATOM 7393  O OD1 . ASP C 1 236 ? -12.815 -68.774 -10.672 1.00 168.20 ? 236 ASP C OD1 1 
ATOM 7394  O OD2 . ASP C 1 236 ? -11.177 -69.037 -12.112 1.00 164.16 ? 236 ASP C OD2 1 
ATOM 7395  N N   . PRO C 1 237 ? -10.271 -71.959 -7.445  1.00 172.66 ? 237 PRO C N   1 
ATOM 7396  C CA  . PRO C 1 237 ? -10.141 -73.075 -6.493  1.00 169.05 ? 237 PRO C CA  1 
ATOM 7397  C C   . PRO C 1 237 ? -10.916 -72.872 -5.201  1.00 161.49 ? 237 PRO C C   1 
ATOM 7398  O O   . PRO C 1 237 ? -10.835 -73.724 -4.310  1.00 157.07 ? 237 PRO C O   1 
ATOM 7399  C CB  . PRO C 1 237 ? -8.629  -73.136 -6.224  1.00 176.12 ? 237 PRO C CB  1 
ATOM 7400  C CG  . PRO C 1 237 ? -8.012  -72.531 -7.424  1.00 175.50 ? 237 PRO C CG  1 
ATOM 7401  C CD  . PRO C 1 237 ? -8.945  -71.430 -7.823  1.00 172.92 ? 237 PRO C CD  1 
ATOM 7402  N N   . LYS C 1 238 ? -11.661 -71.777 -5.068  1.00 158.68 ? 238 LYS C N   1 
ATOM 7403  C CA  . LYS C 1 238 ? -12.427 -71.476 -3.870  1.00 148.73 ? 238 LYS C CA  1 
ATOM 7404  C C   . LYS C 1 238 ? -13.857 -72.003 -3.926  1.00 148.31 ? 238 LYS C C   1 
ATOM 7405  O O   . LYS C 1 238 ? -14.612 -71.802 -2.967  1.00 146.57 ? 238 LYS C O   1 
ATOM 7406  C CB  . LYS C 1 238 ? -12.455 -69.961 -3.631  1.00 147.75 ? 238 LYS C CB  1 
ATOM 7407  C CG  . LYS C 1 238 ? -13.133 -69.177 -4.747  1.00 144.25 ? 238 LYS C CG  1 
ATOM 7408  C CD  . LYS C 1 238 ? -13.215 -67.692 -4.427  1.00 134.77 ? 238 LYS C CD  1 
ATOM 7409  C CE  . LYS C 1 238 ? -14.003 -66.949 -5.497  1.00 117.32 ? 238 LYS C CE  1 
ATOM 7410  N NZ  . LYS C 1 238 ? -14.158 -65.501 -5.184  1.00 92.94  ? 238 LYS C NZ  1 
ATOM 7411  N N   . THR C 1 239 ? -14.248 -72.663 -5.014  1.00 144.20 ? 239 THR C N   1 
ATOM 7412  C CA  . THR C 1 239 ? -15.615 -73.143 -5.179  1.00 130.48 ? 239 THR C CA  1 
ATOM 7413  C C   . THR C 1 239 ? -15.780 -74.622 -4.859  1.00 121.70 ? 239 THR C C   1 
ATOM 7414  O O   . THR C 1 239 ? -16.914 -75.112 -4.855  1.00 115.57 ? 239 THR C O   1 
ATOM 7415  C CB  . THR C 1 239 ? -16.103 -72.894 -6.611  1.00 128.94 ? 239 THR C CB  1 
ATOM 7416  O OG1 . THR C 1 239 ? -17.439 -73.385 -6.745  1.00 123.09 ? 239 THR C OG1 1 
ATOM 7417  C CG2 . THR C 1 239 ? -15.218 -73.618 -7.605  1.00 137.65 ? 239 THR C CG2 1 
ATOM 7418  N N   . GLU C 1 240 ? -14.686 -75.345 -4.608  1.00 131.31 ? 240 GLU C N   1 
ATOM 7419  C CA  . GLU C 1 240 ? -14.795 -76.767 -4.301  1.00 125.42 ? 240 GLU C CA  1 
ATOM 7420  C C   . GLU C 1 240 ? -15.541 -76.986 -2.989  1.00 118.35 ? 240 GLU C C   1 
ATOM 7421  O O   . GLU C 1 240 ? -16.334 -77.926 -2.867  1.00 110.99 ? 240 GLU C O   1 
ATOM 7422  C CB  . GLU C 1 240 ? -13.404 -77.394 -4.248  1.00 135.50 ? 240 GLU C CB  1 
ATOM 7423  C CG  . GLU C 1 240 ? -12.394 -76.707 -5.161  1.00 145.40 ? 240 GLU C CG  1 
ATOM 7424  C CD  . GLU C 1 240 ? -11.043 -77.403 -5.186  1.00 149.61 ? 240 GLU C CD  1 
ATOM 7425  O OE1 . GLU C 1 240 ? -10.988 -78.618 -4.906  1.00 146.51 ? 240 GLU C OE1 1 
ATOM 7426  O OE2 . GLU C 1 240 ? -10.034 -76.730 -5.486  1.00 151.76 ? 240 GLU C OE2 1 
ATOM 7427  N N   . GLN C 1 241 ? -15.298 -76.119 -1.999  1.00 124.60 ? 241 GLN C N   1 
ATOM 7428  C CA  . GLN C 1 241 ? -16.039 -76.195 -0.745  1.00 120.29 ? 241 GLN C CA  1 
ATOM 7429  C C   . GLN C 1 241 ? -17.539 -76.065 -0.985  1.00 110.48 ? 241 GLN C C   1 
ATOM 7430  O O   . GLN C 1 241 ? -18.336 -76.760 -0.344  1.00 98.13  ? 241 GLN C O   1 
ATOM 7431  C CB  . GLN C 1 241 ? -15.555 -75.113 0.221   1.00 120.59 ? 241 GLN C CB  1 
ATOM 7432  C CG  . GLN C 1 241 ? -14.233 -75.420 0.922   1.00 120.04 ? 241 GLN C CG  1 
ATOM 7433  C CD  . GLN C 1 241 ? -13.013 -75.105 0.075   1.00 122.45 ? 241 GLN C CD  1 
ATOM 7434  O OE1 . GLN C 1 241 ? -12.944 -74.068 -0.582  1.00 117.26 ? 241 GLN C OE1 1 
ATOM 7435  N NE2 . GLN C 1 241 ? -12.037 -76.005 0.095   1.00 124.72 ? 241 GLN C NE2 1 
ATOM 7436  N N   . ILE C 1 242 ? -17.940 -75.194 -1.914  1.00 115.63 ? 242 ILE C N   1 
ATOM 7437  C CA  . ILE C 1 242 ? -19.360 -74.981 -2.195  1.00 107.75 ? 242 ILE C CA  1 
ATOM 7438  C C   . ILE C 1 242 ? -20.019 -76.282 -2.636  1.00 100.72 ? 242 ILE C C   1 
ATOM 7439  O O   . ILE C 1 242 ? -21.025 -76.717 -2.062  1.00 93.39  ? 242 ILE C O   1 
ATOM 7440  C CB  . ILE C 1 242 ? -19.536 -73.879 -3.256  1.00 105.14 ? 242 ILE C CB  1 
ATOM 7441  C CG1 . ILE C 1 242 ? -18.872 -72.582 -2.797  1.00 112.02 ? 242 ILE C CG1 1 
ATOM 7442  C CG2 . ILE C 1 242 ? -21.011 -73.653 -3.551  1.00 97.38  ? 242 ILE C CG2 1 
ATOM 7443  C CD1 . ILE C 1 242 ? -19.509 -71.971 -1.573  1.00 107.52 ? 242 ILE C CD1 1 
ATOM 7444  N N   . ILE C 1 243 ? -19.469 -76.921 -3.671  1.00 97.72  ? 243 ILE C N   1 
ATOM 7445  C CA  . ILE C 1 243 ? -20.083 -78.136 -4.201  1.00 101.56 ? 243 ILE C CA  1 
ATOM 7446  C C   . ILE C 1 243 ? -19.973 -79.277 -3.195  1.00 100.81 ? 243 ILE C C   1 
ATOM 7447  O O   . ILE C 1 243 ? -20.895 -80.092 -3.062  1.00 94.17  ? 243 ILE C O   1 
ATOM 7448  C CB  . ILE C 1 243 ? -19.456 -78.506 -5.558  1.00 108.90 ? 243 ILE C CB  1 
ATOM 7449  C CG1 . ILE C 1 243 ? -19.750 -77.418 -6.593  1.00 107.62 ? 243 ILE C CG1 1 
ATOM 7450  C CG2 . ILE C 1 243 ? -19.985 -79.844 -6.049  1.00 89.68  ? 243 ILE C CG2 1 
ATOM 7451  C CD1 . ILE C 1 243 ? -21.230 -77.195 -6.846  1.00 90.24  ? 243 ILE C CD1 1 
ATOM 7452  N N   . ASN C 1 244 ? -18.855 -79.356 -2.469  1.00 101.22 ? 244 ASN C N   1 
ATOM 7453  C CA  . ASN C 1 244 ? -18.716 -80.413 -1.471  1.00 95.45  ? 244 ASN C CA  1 
ATOM 7454  C C   . ASN C 1 244 ? -19.756 -80.265 -0.367  1.00 90.76  ? 244 ASN C C   1 
ATOM 7455  O O   . ASN C 1 244 ? -20.306 -81.262 0.116   1.00 94.35  ? 244 ASN C O   1 
ATOM 7456  C CB  . ASN C 1 244 ? -17.304 -80.409 -0.884  1.00 98.33  ? 244 ASN C CB  1 
ATOM 7457  C CG  . ASN C 1 244 ? -17.060 -81.587 0.041   1.00 90.75  ? 244 ASN C CG  1 
ATOM 7458  O OD1 . ASN C 1 244 ? -17.713 -82.624 -0.074  1.00 87.70  ? 244 ASN C OD1 1 
ATOM 7459  N ND2 . ASN C 1 244 ? -16.119 -81.432 0.965   1.00 92.66  ? 244 ASN C ND2 1 
ATOM 7460  N N   . TRP C 1 245 ? -20.209 -79.038 -0.112  1.00 90.32  ? 245 TRP C N   1 
ATOM 7461  C CA  . TRP C 1 245 ? -21.255 -78.803 0.920   1.00 89.11  ? 245 TRP C CA  1 
ATOM 7462  C C   . TRP C 1 245 ? -22.642 -79.156 0.387   1.00 96.45  ? 245 TRP C C   1 
ATOM 7463  O O   . TRP C 1 245 ? -23.395 -79.777 1.128   1.00 94.42  ? 245 TRP C O   1 
ATOM 7464  C CB  . TRP C 1 245 ? -21.201 -77.345 1.374   1.00 87.25  ? 245 TRP C CB  1 
ATOM 7465  C CG  . TRP C 1 245 ? -22.116 -76.977 2.502   1.00 86.83  ? 245 TRP C CG  1 
ATOM 7466  C CD1 . TRP C 1 245 ? -21.782 -76.870 3.820   1.00 91.63  ? 245 TRP C CD1 1 
ATOM 7467  C CD2 . TRP C 1 245 ? -23.501 -76.598 2.411   1.00 93.20  ? 245 TRP C CD2 1 
ATOM 7468  N NE1 . TRP C 1 245 ? -22.868 -76.490 4.558   1.00 93.44  ? 245 TRP C NE1 1 
ATOM 7469  C CE2 . TRP C 1 245 ? -23.936 -76.312 3.724   1.00 93.35  ? 245 TRP C CE2 1 
ATOM 7470  C CE3 . TRP C 1 245 ? -24.419 -76.491 1.364   1.00 84.74  ? 245 TRP C CE3 1 
ATOM 7471  C CZ2 . TRP C 1 245 ? -25.242 -75.924 4.007   1.00 88.77  ? 245 TRP C CZ2 1 
ATOM 7472  C CZ3 . TRP C 1 245 ? -25.710 -76.110 1.645   1.00 85.35  ? 245 TRP C CZ3 1 
ATOM 7473  C CH2 . TRP C 1 245 ? -26.114 -75.834 2.950   1.00 89.45  ? 245 TRP C CH2 1 
ATOM 7474  N N   . LEU C 1 246 ? -22.953 -78.770 -0.848  1.00 96.60  ? 246 LEU C N   1 
ATOM 7475  C CA  . LEU C 1 246 ? -24.314 -78.955 -1.416  1.00 87.64  ? 246 LEU C CA  1 
ATOM 7476  C C   . LEU C 1 246 ? -24.565 -80.422 -1.737  1.00 90.41  ? 246 LEU C C   1 
ATOM 7477  O O   . LEU C 1 246 ? -25.726 -80.823 -1.716  1.00 84.50  ? 246 LEU C O   1 
ATOM 7478  C CB  . LEU C 1 246 ? -24.415 -78.088 -2.673  1.00 85.03  ? 246 LEU C CB  1 
ATOM 7479  C CG  . LEU C 1 246 ? -25.815 -77.686 -3.118  1.00 79.39  ? 246 LEU C CG  1 
ATOM 7480  C CD1 . LEU C 1 246 ? -26.503 -76.878 -2.037  1.00 77.51  ? 246 LEU C CD1 1 
ATOM 7481  C CD2 . LEU C 1 246 ? -25.743 -76.878 -4.400  1.00 85.31  ? 246 LEU C CD2 1 
ATOM 7482  N N   . ASP C 1 247 ? -23.520 -81.174 -2.022  1.00 95.67  ? 247 ASP C N   1 
ATOM 7483  C CA  . ASP C 1 247 ? -23.727 -82.576 -2.448  1.00 95.93  ? 247 ASP C CA  1 
ATOM 7484  C C   . ASP C 1 247 ? -24.116 -83.425 -1.244  1.00 100.13 ? 247 ASP C C   1 
ATOM 7485  O O   . ASP C 1 247 ? -24.814 -84.425 -1.445  1.00 91.57  ? 247 ASP C O   1 
ATOM 7486  C CB  . ASP C 1 247 ? -22.490 -83.136 -3.145  1.00 94.93  ? 247 ASP C CB  1 
ATOM 7487  C CG  . ASP C 1 247 ? -22.020 -82.309 -4.325  1.00 106.37 ? 247 ASP C CG  1 
ATOM 7488  O OD1 . ASP C 1 247 ? -22.613 -81.243 -4.557  1.00 107.11 ? 247 ASP C OD1 1 
ATOM 7489  O OD2 . ASP C 1 247 ? -21.073 -82.742 -5.006  1.00 107.36 ? 247 ASP C OD2 1 
ATOM 7490  N N   . LYS C 1 248 ? -23.705 -83.017 -0.048  1.00 101.97 ? 248 LYS C N   1 
ATOM 7491  C CA  . LYS C 1 248 ? -23.956 -83.835 1.161   1.00 105.32 ? 248 LYS C CA  1 
ATOM 7492  C C   . LYS C 1 248 ? -25.287 -83.447 1.799   1.00 105.09 ? 248 LYS C C   1 
ATOM 7493  O O   . LYS C 1 248 ? -25.481 -83.756 2.982   1.00 103.47 ? 248 LYS C O   1 
ATOM 7494  C CB  . LYS C 1 248 ? -22.779 -83.678 2.119   1.00 107.15 ? 248 LYS C CB  1 
ATOM 7495  C CG  . LYS C 1 248 ? -22.372 -84.951 2.848   1.00 110.71 ? 248 LYS C CG  1 
ATOM 7496  C CD  . LYS C 1 248 ? -22.413 -86.174 1.960   1.00 114.68 ? 248 LYS C CD  1 
ATOM 7497  C CE  . LYS C 1 248 ? -21.559 -87.312 2.472   1.00 116.28 ? 248 LYS C CE  1 
ATOM 7498  N NZ  . LYS C 1 248 ? -20.118 -86.971 2.435   1.00 117.95 ? 248 LYS C NZ  1 
ATOM 7499  N N   . ARG C 1 249 ? -26.170 -82.807 1.036   1.00 99.29  ? 249 ARG C N   1 
ATOM 7500  C CA  . ARG C 1 249 ? -27.503 -82.405 1.535   1.00 99.66  ? 249 ARG C CA  1 
ATOM 7501  C C   . ARG C 1 249 ? -28.533 -83.038 0.624   1.00 94.57  ? 249 ARG C C   1 
ATOM 7502  O O   . ARG C 1 249 ? -28.205 -83.315 -0.535  1.00 93.09  ? 249 ARG C O   1 
ATOM 7503  C CB  . ARG C 1 249 ? -27.656 -80.888 1.483   1.00 93.39  ? 249 ARG C CB  1 
ATOM 7504  C CG  . ARG C 1 249 ? -26.360 -80.107 1.653   1.00 95.46  ? 249 ARG C CG  1 
ATOM 7505  C CD  . ARG C 1 249 ? -25.791 -80.107 3.057   1.00 88.11  ? 249 ARG C CD  1 
ATOM 7506  N NE  . ARG C 1 249 ? -26.552 -79.257 3.953   1.00 97.57  ? 249 ARG C NE  1 
ATOM 7507  C CZ  . ARG C 1 249 ? -27.258 -79.703 4.982   1.00 97.22  ? 249 ARG C CZ  1 
ATOM 7508  N NH1 . ARG C 1 249 ? -27.472 -80.998 5.120   1.00 92.47  ? 249 ARG C NH1 1 
ATOM 7509  N NH2 . ARG C 1 249 ? -27.761 -78.857 5.861   1.00 96.34  ? 249 ARG C NH2 1 
ATOM 7510  N N   . ALA C 1 250 ? -29.745 -83.209 1.113   1.00 84.01  ? 250 ALA C N   1 
ATOM 7511  C CA  . ALA C 1 250 ? -30.751 -83.947 0.318   1.00 86.85  ? 250 ALA C CA  1 
ATOM 7512  C C   . ALA C 1 250 ? -31.246 -83.154 -0.892  1.00 97.50  ? 250 ALA C C   1 
ATOM 7513  O O   . ALA C 1 250 ? -30.847 -82.008 -1.064  1.00 89.15  ? 250 ALA C O   1 
ATOM 7514  C CB  . ALA C 1 250 ? -31.890 -84.361 1.206   1.00 76.90  ? 250 ALA C CB  1 
ATOM 7515  N N   . GLU C 1 251 ? -32.123 -83.769 -1.677  1.00 96.61  ? 251 GLU C N   1 
ATOM 7516  C CA  . GLU C 1 251 ? -32.566 -83.152 -2.919  1.00 92.80  ? 251 GLU C CA  1 
ATOM 7517  C C   . GLU C 1 251 ? -33.628 -82.093 -2.649  1.00 90.96  ? 251 GLU C C   1 
ATOM 7518  O O   . GLU C 1 251 ? -34.554 -82.313 -1.860  1.00 83.27  ? 251 GLU C O   1 
ATOM 7519  C CB  . GLU C 1 251 ? -33.119 -84.213 -3.873  1.00 99.59  ? 251 GLU C CB  1 
ATOM 7520  C CG  . GLU C 1 251 ? -32.174 -84.595 -5.005  1.00 110.87 ? 251 GLU C CG  1 
ATOM 7521  C CD  . GLU C 1 251 ? -32.850 -85.432 -6.079  1.00 119.62 ? 251 GLU C CD  1 
ATOM 7522  O OE1 . GLU C 1 251 ? -34.061 -85.704 -5.946  1.00 131.88 ? 251 GLU C OE1 1 
ATOM 7523  O OE2 . GLU C 1 251 ? -32.172 -85.815 -7.054  1.00 112.24 ? 251 GLU C OE2 1 
ATOM 7524  N N   . SER C 1 252 ? -33.484 -80.940 -3.304  1.00 85.14  ? 252 SER C N   1 
ATOM 7525  C CA  . SER C 1 252 ? -34.472 -79.861 -3.258  1.00 78.12  ? 252 SER C CA  1 
ATOM 7526  C C   . SER C 1 252 ? -34.737 -79.393 -1.827  1.00 69.41  ? 252 SER C C   1 
ATOM 7527  O O   . SER C 1 252 ? -35.870 -79.079 -1.458  1.00 64.15  ? 252 SER C O   1 
ATOM 7528  C CB  . SER C 1 252 ? -35.774 -80.283 -3.943  1.00 81.30  ? 252 SER C CB  1 
ATOM 7529  O OG  . SER C 1 252 ? -35.536 -80.693 -5.278  1.00 90.36  ? 252 SER C OG  1 
ATOM 7530  N N   . THR C 1 253 ? -33.681 -79.346 -1.016  1.00 78.55  ? 253 THR C N   1 
ATOM 7531  C CA  . THR C 1 253 ? -33.784 -78.871 0.355   1.00 80.14  ? 253 THR C CA  1 
ATOM 7532  C C   . THR C 1 253 ? -32.960 -77.620 0.630   1.00 76.40  ? 253 THR C C   1 
ATOM 7533  O O   . THR C 1 253 ? -33.117 -77.025 1.702   1.00 74.94  ? 253 THR C O   1 
ATOM 7534  C CB  . THR C 1 253 ? -33.358 -79.968 1.343   1.00 79.04  ? 253 THR C CB  1 
ATOM 7535  O OG1 . THR C 1 253 ? -32.001 -80.348 1.083   1.00 78.81  ? 253 THR C OG1 1 
ATOM 7536  C CG2 . THR C 1 253 ? -34.255 -81.188 1.205   1.00 80.85  ? 253 THR C CG2 1 
ATOM 7537  N N   . VAL C 1 254 ? -32.096 -77.209 -0.293  1.00 73.21  ? 254 VAL C N   1 
ATOM 7538  C CA  . VAL C 1 254 ? -31.235 -76.047 -0.116  1.00 70.97  ? 254 VAL C CA  1 
ATOM 7539  C C   . VAL C 1 254 ? -31.861 -74.855 -0.825  1.00 66.53  ? 254 VAL C C   1 
ATOM 7540  O O   . VAL C 1 254 ? -32.366 -74.977 -1.948  1.00 60.89  ? 254 VAL C O   1 
ATOM 7541  C CB  . VAL C 1 254 ? -29.814 -76.319 -0.646  1.00 71.82  ? 254 VAL C CB  1 
ATOM 7542  C CG1 . VAL C 1 254 ? -28.880 -75.174 -0.286  1.00 73.27  ? 254 VAL C CG1 1 
ATOM 7543  C CG2 . VAL C 1 254 ? -29.291 -77.640 -0.105  1.00 73.44  ? 254 VAL C CG2 1 
ATOM 7544  N N   . VAL C 1 255 ? -31.829 -73.700 -0.169  1.00 61.76  ? 255 VAL C N   1 
ATOM 7545  C CA  . VAL C 1 255 ? -32.332 -72.452 -0.726  1.00 55.25  ? 255 VAL C CA  1 
ATOM 7546  C C   . VAL C 1 255 ? -31.133 -71.561 -1.017  1.00 61.71  ? 255 VAL C C   1 
ATOM 7547  O O   . VAL C 1 255 ? -30.352 -71.239 -0.114  1.00 72.03  ? 255 VAL C O   1 
ATOM 7548  C CB  . VAL C 1 255 ? -33.319 -71.763 0.229   1.00 55.37  ? 255 VAL C CB  1 
ATOM 7549  C CG1 . VAL C 1 255 ? -33.893 -70.510 -0.411  1.00 53.87  ? 255 VAL C CG1 1 
ATOM 7550  C CG2 . VAL C 1 255 ? -34.430 -72.724 0.619   1.00 59.65  ? 255 VAL C CG2 1 
ATOM 7551  N N   . PHE C 1 256 ? -30.973 -71.182 -2.280  1.00 54.54  ? 256 PHE C N   1 
ATOM 7552  C CA  . PHE C 1 256 ? -29.888 -70.303 -2.690  1.00 58.96  ? 256 PHE C CA  1 
ATOM 7553  C C   . PHE C 1 256 ? -30.344 -68.855 -2.594  1.00 60.84  ? 256 PHE C C   1 
ATOM 7554  O O   . PHE C 1 256 ? -31.375 -68.480 -3.160  1.00 67.63  ? 256 PHE C O   1 
ATOM 7555  C CB  . PHE C 1 256 ? -29.433 -70.628 -4.112  1.00 66.66  ? 256 PHE C CB  1 
ATOM 7556  C CG  . PHE C 1 256 ? -28.335 -69.737 -4.614  1.00 71.69  ? 256 PHE C CG  1 
ATOM 7557  C CD1 . PHE C 1 256 ? -27.059 -69.821 -4.080  1.00 70.88  ? 256 PHE C CD1 1 
ATOM 7558  C CD2 . PHE C 1 256 ? -28.575 -68.819 -5.621  1.00 65.47  ? 256 PHE C CD2 1 
ATOM 7559  C CE1 . PHE C 1 256 ? -26.046 -69.004 -4.538  1.00 73.13  ? 256 PHE C CE1 1 
ATOM 7560  C CE2 . PHE C 1 256 ? -27.562 -67.996 -6.083  1.00 72.20  ? 256 PHE C CE2 1 
ATOM 7561  C CZ  . PHE C 1 256 ? -26.297 -68.090 -5.543  1.00 74.09  ? 256 PHE C CZ  1 
ATOM 7562  N N   . VAL C 1 257 ? -29.583 -68.046 -1.861  1.00 56.89  ? 257 VAL C N   1 
ATOM 7563  C CA  . VAL C 1 257 ? -29.904 -66.648 -1.625  1.00 55.86  ? 257 VAL C CA  1 
ATOM 7564  C C   . VAL C 1 257 ? -28.798 -65.805 -2.233  1.00 60.10  ? 257 VAL C C   1 
ATOM 7565  O O   . VAL C 1 257 ? -27.613 -66.050 -1.982  1.00 70.91  ? 257 VAL C O   1 
ATOM 7566  C CB  . VAL C 1 257 ? -30.063 -66.342 -0.125  1.00 53.80  ? 257 VAL C CB  1 
ATOM 7567  C CG1 . VAL C 1 257 ? -30.557 -64.910 0.073   1.00 53.95  ? 257 VAL C CG1 1 
ATOM 7568  C CG2 . VAL C 1 257 ? -31.017 -67.339 0.514   1.00 55.18  ? 257 VAL C CG2 1 
ATOM 7569  N N   . CYS C 1 258 ? -29.193 -64.851 -3.087  1.00 60.08  ? 258 CYS C N   1 
ATOM 7570  C CA  . CYS C 1 258 ? -28.219 -63.897 -3.677  1.00 59.97  ? 258 CYS C CA  1 
ATOM 7571  C C   . CYS C 1 258 ? -28.964 -62.668 -4.183  1.00 60.87  ? 258 CYS C C   1 
ATOM 7572  O O   . CYS C 1 258 ? -30.032 -62.838 -4.762  1.00 73.09  ? 258 CYS C O   1 
ATOM 7573  C CB  . CYS C 1 258 ? -27.436 -64.507 -4.824  1.00 63.73  ? 258 CYS C CB  1 
ATOM 7574  S SG  . CYS C 1 258 ? -26.035 -63.483 -5.337  1.00 94.94  ? 258 CYS C SG  1 
ATOM 7575  N N   . PHE C 1 259 ? -28.416 -61.475 -3.948  1.00 66.40  ? 259 PHE C N   1 
ATOM 7576  C CA  . PHE C 1 259 ? -29.049 -60.226 -4.447  1.00 69.45  ? 259 PHE C CA  1 
ATOM 7577  C C   . PHE C 1 259 ? -28.121 -59.584 -5.479  1.00 75.63  ? 259 PHE C C   1 
ATOM 7578  O O   . PHE C 1 259 ? -27.958 -58.352 -5.455  1.00 85.36  ? 259 PHE C O   1 
ATOM 7579  C CB  . PHE C 1 259 ? -29.437 -59.322 -3.274  1.00 69.43  ? 259 PHE C CB  1 
ATOM 7580  C CG  . PHE C 1 259 ? -30.347 -59.998 -2.280  1.00 69.54  ? 259 PHE C CG  1 
ATOM 7581  C CD1 . PHE C 1 259 ? -31.625 -60.391 -2.642  1.00 68.51  ? 259 PHE C CD1 1 
ATOM 7582  C CD2 . PHE C 1 259 ? -29.913 -60.275 -0.992  1.00 79.02  ? 259 PHE C CD2 1 
ATOM 7583  C CE1 . PHE C 1 259 ? -32.457 -61.027 -1.736  1.00 72.92  ? 259 PHE C CE1 1 
ATOM 7584  C CE2 . PHE C 1 259 ? -30.748 -60.908 -0.084  1.00 70.67  ? 259 PHE C CE2 1 
ATOM 7585  C CZ  . PHE C 1 259 ? -32.017 -61.282 -0.458  1.00 64.94  ? 259 PHE C CZ  1 
ATOM 7586  N N   . GLY C 1 260 ? -27.529 -60.408 -6.351  1.00 76.44  ? 260 GLY C N   1 
ATOM 7587  C CA  . GLY C 1 260 ? -26.620 -59.897 -7.395  1.00 84.62  ? 260 GLY C CA  1 
ATOM 7588  C C   . GLY C 1 260 ? -25.506 -59.048 -6.815  1.00 108.12 ? 260 GLY C C   1 
ATOM 7589  O O   . GLY C 1 260 ? -24.863 -59.499 -5.846  1.00 113.55 ? 260 GLY C O   1 
ATOM 7590  N N   . SER C 1 261 ? -25.301 -57.846 -7.363  1.00 105.56 ? 261 SER C N   1 
ATOM 7591  C CA  . SER C 1 261 ? -24.275 -56.913 -6.828  1.00 107.65 ? 261 SER C CA  1 
ATOM 7592  C C   . SER C 1 261 ? -24.851 -55.496 -6.823  1.00 112.44 ? 261 SER C C   1 
ATOM 7593  O O   . SER C 1 261 ? -24.071 -54.542 -6.632  1.00 111.94 ? 261 SER C O   1 
ATOM 7594  C CB  . SER C 1 261 ? -23.011 -56.982 -7.641  1.00 95.23  ? 261 SER C CB  1 
ATOM 7595  O OG  . SER C 1 261 ? -23.259 -56.601 -8.986  1.00 94.91  ? 261 SER C OG  1 
ATOM 7596  N N   . GLU C 1 262 ? -26.166 -55.371 -7.027  1.00 109.82 ? 262 GLU C N   1 
ATOM 7597  C CA  . GLU C 1 262 ? -26.813 -54.034 -7.096  1.00 105.11 ? 262 GLU C CA  1 
ATOM 7598  C C   . GLU C 1 262 ? -26.682 -53.324 -5.744  1.00 105.78 ? 262 GLU C C   1 
ATOM 7599  O O   . GLU C 1 262 ? -26.216 -52.168 -5.733  1.00 112.05 ? 262 GLU C O   1 
ATOM 7600  C CB  . GLU C 1 262 ? -28.282 -54.182 -7.492  1.00 107.05 ? 262 GLU C CB  1 
ATOM 7601  C CG  . GLU C 1 262 ? -28.478 -54.686 -8.910  1.00 102.19 ? 262 GLU C CG  1 
ATOM 7602  C CD  . GLU C 1 262 ? -29.923 -54.916 -9.323  1.00 92.92  ? 262 GLU C CD  1 
ATOM 7603  O OE1 . GLU C 1 262 ? -30.804 -54.866 -8.445  1.00 97.74  ? 262 GLU C OE1 1 
ATOM 7604  O OE2 . GLU C 1 262 ? -30.164 -55.137 -10.524 1.00 83.97  ? 262 GLU C OE2 1 
ATOM 7605  N N   . TYR C 1 263 ? -27.078 -53.990 -4.654  1.00 107.27 ? 263 TYR C N   1 
ATOM 7606  C CA  . TYR C 1 263 ? -27.042 -53.358 -3.316  1.00 110.35 ? 263 TYR C CA  1 
ATOM 7607  C C   . TYR C 1 263 ? -26.586 -54.379 -2.273  1.00 119.42 ? 263 TYR C C   1 
ATOM 7608  O O   . TYR C 1 263 ? -27.252 -55.428 -2.146  1.00 121.81 ? 263 TYR C O   1 
ATOM 7609  C CB  . TYR C 1 263 ? -28.412 -52.789 -2.944  1.00 113.22 ? 263 TYR C CB  1 
ATOM 7610  C CG  . TYR C 1 263 ? -29.500 -53.835 -2.828  1.00 113.96 ? 263 TYR C CG  1 
ATOM 7611  C CD1 . TYR C 1 263 ? -29.742 -54.481 -1.621  1.00 113.80 ? 263 TYR C CD1 1 
ATOM 7612  C CD2 . TYR C 1 263 ? -30.282 -54.172 -3.923  1.00 118.01 ? 263 TYR C CD2 1 
ATOM 7613  C CE1 . TYR C 1 263 ? -30.734 -55.435 -1.511  1.00 113.40 ? 263 TYR C CE1 1 
ATOM 7614  C CE2 . TYR C 1 263 ? -31.278 -55.128 -3.821  1.00 114.72 ? 263 TYR C CE2 1 
ATOM 7615  C CZ  . TYR C 1 263 ? -31.499 -55.755 -2.613  1.00 112.88 ? 263 TYR C CZ  1 
ATOM 7616  O OH  . TYR C 1 263 ? -32.487 -56.707 -2.506  1.00 104.72 ? 263 TYR C OH  1 
ATOM 7617  N N   . PHE C 1 264 ? -25.490 -54.089 -1.567  1.00 114.35 ? 264 PHE C N   1 
ATOM 7618  C CA  . PHE C 1 264 ? -25.022 -54.981 -0.473  1.00 118.54 ? 264 PHE C CA  1 
ATOM 7619  C C   . PHE C 1 264 ? -25.971 -54.812 0.715   1.00 117.09 ? 264 PHE C C   1 
ATOM 7620  O O   . PHE C 1 264 ? -25.649 -55.363 1.792   1.00 115.98 ? 264 PHE C O   1 
ATOM 7621  C CB  . PHE C 1 264 ? -23.577 -54.640 -0.095  1.00 118.65 ? 264 PHE C CB  1 
ATOM 7622  C CG  . PHE C 1 264 ? -23.395 -53.397 0.744   1.00 120.81 ? 264 PHE C CG  1 
ATOM 7623  C CD1 . PHE C 1 264 ? -23.599 -52.135 0.209   1.00 121.05 ? 264 PHE C CD1 1 
ATOM 7624  C CD2 . PHE C 1 264 ? -23.005 -53.490 2.072   1.00 125.03 ? 264 PHE C CD2 1 
ATOM 7625  C CE1 . PHE C 1 264 ? -23.432 -50.998 0.984   1.00 130.19 ? 264 PHE C CE1 1 
ATOM 7626  C CE2 . PHE C 1 264 ? -22.842 -52.352 2.846   1.00 120.39 ? 264 PHE C CE2 1 
ATOM 7627  C CZ  . PHE C 1 264 ? -23.053 -51.108 2.300   1.00 125.93 ? 264 PHE C CZ  1 
ATOM 7628  N N   . LEU C 1 265 ? -27.082 -54.084 0.520   1.00 110.56 ? 265 LEU C N   1 
ATOM 7629  C CA  . LEU C 1 265 ? -28.052 -53.789 1.615   1.00 109.44 ? 265 LEU C CA  1 
ATOM 7630  C C   . LEU C 1 265 ? -27.329 -52.967 2.686   1.00 113.30 ? 265 LEU C C   1 
ATOM 7631  O O   . LEU C 1 265 ? -26.537 -52.082 2.305   1.00 121.77 ? 265 LEU C O   1 
ATOM 7632  C CB  . LEU C 1 265 ? -28.662 -55.079 2.181   1.00 107.07 ? 265 LEU C CB  1 
ATOM 7633  C CG  . LEU C 1 265 ? -29.620 -54.901 3.359   1.00 105.89 ? 265 LEU C CG  1 
ATOM 7634  C CD1 . LEU C 1 265 ? -30.843 -54.095 2.953   1.00 106.52 ? 265 LEU C CD1 1 
ATOM 7635  C CD2 . LEU C 1 265 ? -30.031 -56.249 3.935   1.00 99.98  ? 265 LEU C CD2 1 
ATOM 7636  N N   . SER C 1 266 ? -27.599 -53.241 3.963   1.00 104.49 ? 266 SER C N   1 
ATOM 7637  C CA  . SER C 1 266 ? -26.909 -52.529 5.070   1.00 107.23 ? 266 SER C CA  1 
ATOM 7638  C C   . SER C 1 266 ? -26.954 -53.419 6.311   1.00 104.90 ? 266 SER C C   1 
ATOM 7639  O O   . SER C 1 266 ? -27.666 -54.412 6.262   1.00 101.38 ? 266 SER C O   1 
ATOM 7640  C CB  . SER C 1 266 ? -27.555 -51.198 5.345   1.00 99.84  ? 266 SER C CB  1 
ATOM 7641  O OG  . SER C 1 266 ? -28.821 -51.372 5.963   1.00 97.99  ? 266 SER C OG  1 
ATOM 7642  N N   . ASN C 1 267 ? -26.217 -53.074 7.367   1.00 103.25 ? 267 ASN C N   1 
ATOM 7643  C CA  . ASN C 1 267 ? -26.264 -53.841 8.640   1.00 103.23 ? 267 ASN C CA  1 
ATOM 7644  C C   . ASN C 1 267 ? -27.705 -53.897 9.146   1.00 102.15 ? 267 ASN C C   1 
ATOM 7645  O O   . ASN C 1 267 ? -28.001 -54.753 9.993   1.00 101.86 ? 267 ASN C O   1 
ATOM 7646  C CB  . ASN C 1 267 ? -25.290 -53.307 9.691   1.00 104.24 ? 267 ASN C CB  1 
ATOM 7647  C CG  . ASN C 1 267 ? -25.771 -52.057 10.396  1.00 106.21 ? 267 ASN C CG  1 
ATOM 7648  O OD1 . ASN C 1 267 ? -26.205 -52.117 11.543  1.00 108.14 ? 267 ASN C OD1 1 
ATOM 7649  N ND2 . ASN C 1 267 ? -25.671 -50.920 9.729   1.00 106.12 ? 267 ASN C ND2 1 
ATOM 7650  N N   . GLU C 1 268 ? -28.567 -53.019 8.635   1.00 105.39 ? 268 GLU C N   1 
ATOM 7651  C CA  . GLU C 1 268 ? -29.956 -52.987 9.136   1.00 105.05 ? 268 GLU C CA  1 
ATOM 7652  C C   . GLU C 1 268 ? -30.777 -53.957 8.296   1.00 101.41 ? 268 GLU C C   1 
ATOM 7653  O O   . GLU C 1 268 ? -31.698 -54.588 8.843   1.00 103.27 ? 268 GLU C O   1 
ATOM 7654  C CB  . GLU C 1 268 ? -30.507 -51.570 9.018   1.00 101.56 ? 268 GLU C CB  1 
ATOM 7655  C CG  . GLU C 1 268 ? -30.388 -50.770 10.302  1.00 100.77 ? 268 GLU C CG  1 
ATOM 7656  C CD  . GLU C 1 268 ? -28.998 -50.227 10.588  1.00 109.05 ? 268 GLU C CD  1 
ATOM 7657  O OE1 . GLU C 1 268 ? -28.323 -49.807 9.630   1.00 112.17 ? 268 GLU C OE1 1 
ATOM 7658  O OE2 . GLU C 1 268 ? -28.593 -50.230 11.767  1.00 116.50 ? 268 GLU C OE2 1 
ATOM 7659  N N   . GLU C 1 269 ? -30.439 -54.057 7.015   1.00 100.26 ? 269 GLU C N   1 
ATOM 7660  C CA  . GLU C 1 269 ? -31.221 -54.928 6.113   1.00 103.01 ? 269 GLU C CA  1 
ATOM 7661  C C   . GLU C 1 269 ? -30.602 -56.323 6.106   1.00 101.78 ? 269 GLU C C   1 
ATOM 7662  O O   . GLU C 1 269 ? -31.372 -57.282 5.977   1.00 96.04  ? 269 GLU C O   1 
ATOM 7663  C CB  . GLU C 1 269 ? -31.348 -54.276 4.742   1.00 101.93 ? 269 GLU C CB  1 
ATOM 7664  C CG  . GLU C 1 269 ? -31.822 -52.835 4.817   1.00 108.44 ? 269 GLU C CG  1 
ATOM 7665  C CD  . GLU C 1 269 ? -32.767 -52.403 3.707   1.00 114.09 ? 269 GLU C CD  1 
ATOM 7666  O OE1 . GLU C 1 269 ? -33.532 -53.256 3.215   1.00 111.66 ? 269 GLU C OE1 1 
ATOM 7667  O OE2 . GLU C 1 269 ? -32.732 -51.215 3.331   1.00 114.11 ? 269 GLU C OE2 1 
ATOM 7668  N N   . LEU C 1 270 ? -29.275 -56.438 6.245   1.00 98.58  ? 270 LEU C N   1 
ATOM 7669  C CA  . LEU C 1 270 ? -28.754 -57.795 6.348   1.00 91.26  ? 270 LEU C CA  1 
ATOM 7670  C C   . LEU C 1 270 ? -29.357 -58.533 7.534   1.00 94.14  ? 270 LEU C C   1 
ATOM 7671  O O   . LEU C 1 270 ? -29.525 -59.755 7.480   1.00 91.44  ? 270 LEU C O   1 
ATOM 7672  C CB  . LEU C 1 270 ? -27.229 -57.773 6.476   1.00 91.39  ? 270 LEU C CB  1 
ATOM 7673  C CG  . LEU C 1 270 ? -26.389 -57.381 5.259   1.00 84.24  ? 270 LEU C CG  1 
ATOM 7674  C CD1 . LEU C 1 270 ? -24.956 -57.096 5.680   1.00 90.07  ? 270 LEU C CD1 1 
ATOM 7675  C CD2 . LEU C 1 270 ? -26.430 -58.465 4.199   1.00 82.08  ? 270 LEU C CD2 1 
ATOM 7676  N N   . GLU C 1 271 ? -29.682 -57.811 8.609   1.00 95.28  ? 271 GLU C N   1 
ATOM 7677  C CA  . GLU C 1 271 ? -30.238 -58.458 9.795   1.00 93.78  ? 271 GLU C CA  1 
ATOM 7678  C C   . GLU C 1 271 ? -31.582 -59.113 9.495   1.00 95.25  ? 271 GLU C C   1 
ATOM 7679  O O   . GLU C 1 271 ? -31.838 -60.259 9.897   1.00 95.09  ? 271 GLU C O   1 
ATOM 7680  C CB  . GLU C 1 271 ? -30.376 -57.442 10.930  1.00 102.05 ? 271 GLU C CB  1 
ATOM 7681  C CG  . GLU C 1 271 ? -29.309 -57.572 12.003  1.00 105.15 ? 271 GLU C CG  1 
ATOM 7682  C CD  . GLU C 1 271 ? -29.431 -58.868 12.780  1.00 105.96 ? 271 GLU C CD  1 
ATOM 7683  O OE1 . GLU C 1 271 ? -30.558 -59.210 13.188  1.00 103.25 ? 271 GLU C OE1 1 
ATOM 7684  O OE2 . GLU C 1 271 ? -28.400 -59.545 12.975  1.00 105.37 ? 271 GLU C OE2 1 
ATOM 7685  N N   . GLU C 1 272 ? -32.464 -58.393 8.794   1.00 93.76  ? 272 GLU C N   1 
ATOM 7686  C CA  . GLU C 1 272 ? -33.813 -58.885 8.548   1.00 88.81  ? 272 GLU C CA  1 
ATOM 7687  C C   . GLU C 1 272 ? -33.827 -60.123 7.660   1.00 83.08  ? 272 GLU C C   1 
ATOM 7688  O O   . GLU C 1 272 ? -34.794 -60.890 7.707   1.00 87.75  ? 272 GLU C O   1 
ATOM 7689  C CB  . GLU C 1 272 ? -34.671 -57.787 7.916   1.00 95.31  ? 272 GLU C CB  1 
ATOM 7690  C CG  . GLU C 1 272 ? -34.782 -56.508 8.739   1.00 98.64  ? 272 GLU C CG  1 
ATOM 7691  C CD  . GLU C 1 272 ? -35.874 -56.567 9.797   1.00 95.32  ? 272 GLU C CD  1 
ATOM 7692  O OE1 . GLU C 1 272 ? -36.356 -57.677 10.108  1.00 91.22  ? 272 GLU C OE1 1 
ATOM 7693  O OE2 . GLU C 1 272 ? -36.254 -55.495 10.315  1.00 97.69  ? 272 GLU C OE2 1 
ATOM 7694  N N   . VAL C 1 273 ? -32.788 -60.334 6.853   1.00 84.82  ? 273 VAL C N   1 
ATOM 7695  C CA  . VAL C 1 273 ? -32.744 -61.503 5.981   1.00 82.42  ? 273 VAL C CA  1 
ATOM 7696  C C   . VAL C 1 273 ? -31.974 -62.620 6.673   1.00 86.03  ? 273 VAL C C   1 
ATOM 7697  O O   . VAL C 1 273 ? -32.300 -63.800 6.509   1.00 78.96  ? 273 VAL C O   1 
ATOM 7698  C CB  . VAL C 1 273 ? -32.139 -61.163 4.603   1.00 77.46  ? 273 VAL C CB  1 
ATOM 7699  C CG1 . VAL C 1 273 ? -32.878 -59.988 3.977   1.00 79.87  ? 273 VAL C CG1 1 
ATOM 7700  C CG2 . VAL C 1 273 ? -30.650 -60.866 4.709   1.00 76.06  ? 273 VAL C CG2 1 
ATOM 7701  N N   . ALA C 1 274 ? -30.985 -62.263 7.499   1.00 89.64  ? 274 ALA C N   1 
ATOM 7702  C CA  . ALA C 1 274 ? -30.219 -63.282 8.208   1.00 76.64  ? 274 ALA C CA  1 
ATOM 7703  C C   . ALA C 1 274 ? -31.081 -63.988 9.248   1.00 79.45  ? 274 ALA C C   1 
ATOM 7704  O O   . ALA C 1 274 ? -31.118 -65.223 9.306   1.00 78.09  ? 274 ALA C O   1 
ATOM 7705  C CB  . ALA C 1 274 ? -28.988 -62.656 8.859   1.00 79.06  ? 274 ALA C CB  1 
ATOM 7706  N N   . ILE C 1 275 ? -31.788 -63.219 10.080  1.00 78.11  ? 275 ILE C N   1 
ATOM 7707  C CA  . ILE C 1 275 ? -32.649 -63.850 11.076  1.00 87.17  ? 275 ILE C CA  1 
ATOM 7708  C C   . ILE C 1 275 ? -33.845 -64.517 10.403  1.00 89.13  ? 275 ILE C C   1 
ATOM 7709  O O   . ILE C 1 275 ? -34.357 -65.532 10.893  1.00 88.06  ? 275 ILE C O   1 
ATOM 7710  C CB  . ILE C 1 275 ? -33.079 -62.823 12.140  1.00 87.93  ? 275 ILE C CB  1 
ATOM 7711  C CG1 . ILE C 1 275 ? -31.845 -62.179 12.770  1.00 87.59  ? 275 ILE C CG1 1 
ATOM 7712  C CG2 . ILE C 1 275 ? -33.924 -63.483 13.218  1.00 84.39  ? 275 ILE C CG2 1 
ATOM 7713  C CD1 . ILE C 1 275 ? -30.870 -63.179 13.366  1.00 81.76  ? 275 ILE C CD1 1 
ATOM 7714  N N   . GLY C 1 276 ? -34.299 -63.978 9.267   1.00 85.36  ? 276 GLY C N   1 
ATOM 7715  C CA  . GLY C 1 276 ? -35.351 -64.637 8.515   1.00 83.61  ? 276 GLY C CA  1 
ATOM 7716  C C   . GLY C 1 276 ? -34.924 -65.979 7.954   1.00 85.03  ? 276 GLY C C   1 
ATOM 7717  O O   . GLY C 1 276 ? -35.736 -66.905 7.857   1.00 88.16  ? 276 GLY C O   1 
ATOM 7718  N N   . LEU C 1 277 ? -33.654 -66.106 7.567   1.00 82.59  ? 277 LEU C N   1 
ATOM 7719  C CA  . LEU C 1 277 ? -33.120 -67.395 7.148   1.00 81.13  ? 277 LEU C CA  1 
ATOM 7720  C C   . LEU C 1 277 ? -32.873 -68.317 8.333   1.00 91.78  ? 277 LEU C C   1 
ATOM 7721  O O   . LEU C 1 277 ? -32.948 -69.543 8.183   1.00 94.29  ? 277 LEU C O   1 
ATOM 7722  C CB  . LEU C 1 277 ? -31.821 -67.199 6.364   1.00 74.84  ? 277 LEU C CB  1 
ATOM 7723  C CG  . LEU C 1 277 ? -31.954 -66.645 4.944   1.00 72.72  ? 277 LEU C CG  1 
ATOM 7724  C CD1 . LEU C 1 277 ? -30.588 -66.292 4.380   1.00 71.75  ? 277 LEU C CD1 1 
ATOM 7725  C CD2 . LEU C 1 277 ? -32.657 -67.650 4.049   1.00 79.17  ? 277 LEU C CD2 1 
ATOM 7726  N N   . GLU C 1 278 ? -32.578 -67.757 9.510   1.00 85.98  ? 278 GLU C N   1 
ATOM 7727  C CA  . GLU C 1 278 ? -32.367 -68.597 10.687  1.00 82.95  ? 278 GLU C CA  1 
ATOM 7728  C C   . GLU C 1 278 ? -33.657 -69.287 11.108  1.00 88.84  ? 278 GLU C C   1 
ATOM 7729  O O   . GLU C 1 278 ? -33.682 -70.507 11.309  1.00 94.46  ? 278 GLU C O   1 
ATOM 7730  C CB  . GLU C 1 278 ? -31.801 -67.767 11.842  1.00 96.00  ? 278 GLU C CB  1 
ATOM 7731  C CG  . GLU C 1 278 ? -31.571 -68.578 13.112  1.00 102.85 ? 278 GLU C CG  1 
ATOM 7732  C CD  . GLU C 1 278 ? -30.947 -67.761 14.229  1.00 104.58 ? 278 GLU C CD  1 
ATOM 7733  O OE1 . GLU C 1 278 ? -30.671 -66.562 14.012  1.00 97.86  ? 278 GLU C OE1 1 
ATOM 7734  O OE2 . GLU C 1 278 ? -30.728 -68.321 15.324  1.00 107.96 ? 278 GLU C OE2 1 
ATOM 7735  N N   . ILE C 1 279 ? -34.747 -68.524 11.248  1.00 89.95  ? 279 ILE C N   1 
ATOM 7736  C CA  . ILE C 1 279 ? -36.019 -69.101 11.683  1.00 85.50  ? 279 ILE C CA  1 
ATOM 7737  C C   . ILE C 1 279 ? -36.750 -69.823 10.563  1.00 85.40  ? 279 ILE C C   1 
ATOM 7738  O O   . ILE C 1 279 ? -37.817 -70.402 10.809  1.00 86.66  ? 279 ILE C O   1 
ATOM 7739  C CB  . ILE C 1 279 ? -36.949 -68.026 12.282  1.00 86.84  ? 279 ILE C CB  1 
ATOM 7740  C CG1 . ILE C 1 279 ? -37.387 -67.031 11.207  1.00 77.24  ? 279 ILE C CG1 1 
ATOM 7741  C CG2 . ILE C 1 279 ? -36.255 -67.301 13.423  1.00 82.47  ? 279 ILE C CG2 1 
ATOM 7742  C CD1 . ILE C 1 279 ? -38.419 -66.036 11.693  1.00 82.98  ? 279 ILE C CD1 1 
ATOM 7743  N N   . SER C 1 280 ? -36.212 -69.810 9.342   1.00 90.87  ? 280 SER C N   1 
ATOM 7744  C CA  . SER C 1 280 ? -36.817 -70.571 8.254   1.00 89.34  ? 280 SER C CA  1 
ATOM 7745  C C   . SER C 1 280 ? -36.629 -72.071 8.428   1.00 90.66  ? 280 SER C C   1 
ATOM 7746  O O   . SER C 1 280 ? -37.402 -72.847 7.858   1.00 93.01  ? 280 SER C O   1 
ATOM 7747  C CB  . SER C 1 280 ? -36.231 -70.125 6.914   1.00 84.59  ? 280 SER C CB  1 
ATOM 7748  O OG  . SER C 1 280 ? -36.512 -68.758 6.665   1.00 95.00  ? 280 SER C OG  1 
ATOM 7749  N N   . THR C 1 281 ? -35.625 -72.488 9.205   1.00 89.38  ? 281 THR C N   1 
ATOM 7750  C CA  . THR C 1 281 ? -35.353 -73.899 9.495   1.00 90.57  ? 281 THR C CA  1 
ATOM 7751  C C   . THR C 1 281 ? -35.197 -74.713 8.209   1.00 90.01  ? 281 THR C C   1 
ATOM 7752  O O   . THR C 1 281 ? -35.799 -75.775 8.039   1.00 92.24  ? 281 THR C O   1 
ATOM 7753  C CB  . THR C 1 281 ? -36.438 -74.500 10.396  1.00 98.21  ? 281 THR C CB  1 
ATOM 7754  O OG1 . THR C 1 281 ? -37.668 -74.612 9.669   1.00 102.56 ? 281 THR C OG1 1 
ATOM 7755  C CG2 . THR C 1 281 ? -36.655 -73.625 11.623  1.00 95.79  ? 281 THR C CG2 1 
ATOM 7756  N N   . VAL C 1 282 ? -34.370 -74.205 7.294   1.00 87.03  ? 282 VAL C N   1 
ATOM 7757  C CA  . VAL C 1 282 ? -34.089 -74.886 6.039   1.00 81.79  ? 282 VAL C CA  1 
ATOM 7758  C C   . VAL C 1 282 ? -32.661 -74.566 5.625   1.00 79.24  ? 282 VAL C C   1 
ATOM 7759  O O   . VAL C 1 282 ? -32.134 -73.491 5.928   1.00 81.76  ? 282 VAL C O   1 
ATOM 7760  C CB  . VAL C 1 282 ? -35.104 -74.495 4.936   1.00 77.30  ? 282 VAL C CB  1 
ATOM 7761  C CG1 . VAL C 1 282 ? -34.861 -73.075 4.447   1.00 79.72  ? 282 VAL C CG1 1 
ATOM 7762  C CG2 . VAL C 1 282 ? -35.062 -75.490 3.784   1.00 80.43  ? 282 VAL C CG2 1 
ATOM 7763  N N   . ASN C 1 283 ? -32.026 -75.519 4.947   1.00 70.52  ? 283 ASN C N   1 
ATOM 7764  C CA  . ASN C 1 283 ? -30.663 -75.327 4.473   1.00 81.58  ? 283 ASN C CA  1 
ATOM 7765  C C   . ASN C 1 283 ? -30.612 -74.201 3.446   1.00 76.74  ? 283 ASN C C   1 
ATOM 7766  O O   . ASN C 1 283 ? -31.544 -74.001 2.666   1.00 76.86  ? 283 ASN C O   1 
ATOM 7767  C CB  . ASN C 1 283 ? -30.129 -76.619 3.854   1.00 86.88  ? 283 ASN C CB  1 
ATOM 7768  C CG  . ASN C 1 283 ? -30.379 -77.829 4.729   1.00 91.01  ? 283 ASN C CG  1 
ATOM 7769  O OD1 . ASN C 1 283 ? -30.264 -77.756 5.953   1.00 97.12  ? 283 ASN C OD1 1 
ATOM 7770  N ND2 . ASN C 1 283 ? -30.727 -78.947 4.104   1.00 89.95  ? 283 ASN C ND2 1 
ATOM 7771  N N   . PHE C 1 284 ? -29.503 -73.469 3.438   1.00 76.02  ? 284 PHE C N   1 
ATOM 7772  C CA  . PHE C 1 284 ? -29.380 -72.344 2.524   1.00 73.24  ? 284 PHE C CA  1 
ATOM 7773  C C   . PHE C 1 284 ? -27.918 -72.104 2.179   1.00 72.52  ? 284 PHE C C   1 
ATOM 7774  O O   . PHE C 1 284 ? -27.013 -72.447 2.945   1.00 72.63  ? 284 PHE C O   1 
ATOM 7775  C CB  . PHE C 1 284 ? -29.996 -71.068 3.116   1.00 72.49  ? 284 PHE C CB  1 
ATOM 7776  C CG  . PHE C 1 284 ? -29.229 -70.506 4.278   1.00 78.73  ? 284 PHE C CG  1 
ATOM 7777  C CD1 . PHE C 1 284 ? -29.443 -70.981 5.560   1.00 83.06  ? 284 PHE C CD1 1 
ATOM 7778  C CD2 . PHE C 1 284 ? -28.296 -69.499 4.089   1.00 80.06  ? 284 PHE C CD2 1 
ATOM 7779  C CE1 . PHE C 1 284 ? -28.738 -70.468 6.630   1.00 87.31  ? 284 PHE C CE1 1 
ATOM 7780  C CE2 . PHE C 1 284 ? -27.587 -68.983 5.155   1.00 82.88  ? 284 PHE C CE2 1 
ATOM 7781  C CZ  . PHE C 1 284 ? -27.809 -69.466 6.427   1.00 82.13  ? 284 PHE C CZ  1 
ATOM 7782  N N   . ILE C 1 285 ? -27.708 -71.515 1.009   1.00 67.55  ? 285 ILE C N   1 
ATOM 7783  C CA  . ILE C 1 285 ? -26.419 -70.969 0.602   1.00 62.50  ? 285 ILE C CA  1 
ATOM 7784  C C   . ILE C 1 285 ? -26.664 -69.498 0.295   1.00 63.79  ? 285 ILE C C   1 
ATOM 7785  O O   . ILE C 1 285 ? -27.164 -69.153 -0.779  1.00 73.90  ? 285 ILE C O   1 
ATOM 7786  C CB  . ILE C 1 285 ? -25.822 -71.702 -0.604  1.00 60.73  ? 285 ILE C CB  1 
ATOM 7787  C CG1 . ILE C 1 285 ? -25.659 -73.188 -0.295  1.00 60.17  ? 285 ILE C CG1 1 
ATOM 7788  C CG2 . ILE C 1 285 ? -24.482 -71.088 -0.983  1.00 62.39  ? 285 ILE C CG2 1 
ATOM 7789  C CD1 . ILE C 1 285 ? -24.970 -73.966 -1.395  1.00 57.29  ? 285 ILE C CD1 1 
ATOM 7790  N N   . TRP C 1 286 ? -26.338 -68.630 1.248   1.00 67.27  ? 286 TRP C N   1 
ATOM 7791  C CA  . TRP C 1 286 ? -26.573 -67.193 1.125   1.00 67.08  ? 286 TRP C CA  1 
ATOM 7792  C C   . TRP C 1 286 ? -25.256 -66.531 0.736   1.00 68.40  ? 286 TRP C C   1 
ATOM 7793  O O   . TRP C 1 286 ? -24.392 -66.296 1.580   1.00 75.49  ? 286 TRP C O   1 
ATOM 7794  C CB  . TRP C 1 286 ? -27.122 -66.626 2.428   1.00 74.07  ? 286 TRP C CB  1 
ATOM 7795  C CG  . TRP C 1 286 ? -27.205 -65.132 2.472   1.00 73.39  ? 286 TRP C CG  1 
ATOM 7796  C CD1 . TRP C 1 286 ? -27.361 -64.282 1.412   1.00 67.58  ? 286 TRP C CD1 1 
ATOM 7797  C CD2 . TRP C 1 286 ? -27.124 -64.307 3.638   1.00 76.05  ? 286 TRP C CD2 1 
ATOM 7798  N NE1 . TRP C 1 286 ? -27.386 -62.980 1.849   1.00 66.67  ? 286 TRP C NE1 1 
ATOM 7799  C CE2 . TRP C 1 286 ? -27.244 -62.969 3.212   1.00 71.10  ? 286 TRP C CE2 1 
ATOM 7800  C CE3 . TRP C 1 286 ? -26.966 -64.569 5.002   1.00 78.71  ? 286 TRP C CE3 1 
ATOM 7801  C CZ2 . TRP C 1 286 ? -27.208 -61.897 4.103   1.00 76.64  ? 286 TRP C CZ2 1 
ATOM 7802  C CZ3 . TRP C 1 286 ? -26.931 -63.503 5.883   1.00 81.78  ? 286 TRP C CZ3 1 
ATOM 7803  C CH2 . TRP C 1 286 ? -27.053 -62.184 5.431   1.00 82.16  ? 286 TRP C CH2 1 
ATOM 7804  N N   . ALA C 1 287 ? -25.111 -66.225 -0.552  1.00 58.35  ? 287 ALA C N   1 
ATOM 7805  C CA  . ALA C 1 287 ? -23.917 -65.566 -1.066  1.00 59.38  ? 287 ALA C CA  1 
ATOM 7806  C C   . ALA C 1 287 ? -24.108 -64.060 -0.951  1.00 66.91  ? 287 ALA C C   1 
ATOM 7807  O O   . ALA C 1 287 ? -24.949 -63.479 -1.648  1.00 61.82  ? 287 ALA C O   1 
ATOM 7808  C CB  . ALA C 1 287 ? -23.651 -65.981 -2.509  1.00 65.08  ? 287 ALA C CB  1 
ATOM 7809  N N   . VAL C 1 288 ? -23.374 -63.456 -0.011  1.00 78.26  ? 288 VAL C N   1 
ATOM 7810  C CA  . VAL C 1 288 ? -23.540 -62.009 0.312   1.00 80.96  ? 288 VAL C CA  1 
ATOM 7811  C C   . VAL C 1 288 ? -22.594 -61.160 -0.537  1.00 80.86  ? 288 VAL C C   1 
ATOM 7812  O O   . VAL C 1 288 ? -21.960 -61.737 -1.408  1.00 85.73  ? 288 VAL C O   1 
ATOM 7813  C CB  . VAL C 1 288 ? -23.370 -61.791 1.827   1.00 85.61  ? 288 VAL C CB  1 
ATOM 7814  C CG1 . VAL C 1 288 ? -21.918 -61.705 2.270   1.00 85.67  ? 288 VAL C CG1 1 
ATOM 7815  C CG2 . VAL C 1 288 ? -24.182 -60.620 2.350   1.00 85.65  ? 288 VAL C CG2 1 
ATOM 7816  N N   . PHE C 1 303 ? -27.941 -66.516 14.360  1.00 106.81 ? 303 PHE C N   1 
ATOM 7817  C CA  . PHE C 1 303 ? -27.106 -66.555 13.133  1.00 109.14 ? 303 PHE C CA  1 
ATOM 7818  C C   . PHE C 1 303 ? -25.641 -66.457 13.541  1.00 103.27 ? 303 PHE C C   1 
ATOM 7819  O O   . PHE C 1 303 ? -25.017 -67.515 13.682  1.00 102.80 ? 303 PHE C O   1 
ATOM 7820  C CB  . PHE C 1 303 ? -27.477 -65.404 12.197  1.00 104.65 ? 303 PHE C CB  1 
ATOM 7821  C CG  . PHE C 1 303 ? -27.329 -65.713 10.732  1.00 95.31  ? 303 PHE C CG  1 
ATOM 7822  C CD1 . PHE C 1 303 ? -28.267 -66.492 10.077  1.00 88.66  ? 303 PHE C CD1 1 
ATOM 7823  C CD2 . PHE C 1 303 ? -26.251 -65.228 10.014  1.00 91.34  ? 303 PHE C CD2 1 
ATOM 7824  C CE1 . PHE C 1 303 ? -28.130 -66.776 8.730   1.00 87.10  ? 303 PHE C CE1 1 
ATOM 7825  C CE2 . PHE C 1 303 ? -26.114 -65.516 8.667   1.00 92.84  ? 303 PHE C CE2 1 
ATOM 7826  C CZ  . PHE C 1 303 ? -27.052 -66.291 8.029   1.00 89.30  ? 303 PHE C CZ  1 
ATOM 7827  N N   . VAL C 1 304 ? -25.123 -65.236 13.704  1.00 111.52 ? 304 VAL C N   1 
ATOM 7828  C CA  . VAL C 1 304 ? -23.695 -64.999 14.086  1.00 118.82 ? 304 VAL C CA  1 
ATOM 7829  C C   . VAL C 1 304 ? -22.754 -65.958 13.326  1.00 114.91 ? 304 VAL C C   1 
ATOM 7830  O O   . VAL C 1 304 ? -21.658 -66.244 13.853  1.00 107.00 ? 304 VAL C O   1 
ATOM 7831  C CB  . VAL C 1 304 ? -23.504 -64.943 15.618  1.00 109.40 ? 304 VAL C CB  1 
ATOM 7832  C CG1 . VAL C 1 304 ? -23.400 -66.306 16.285  1.00 112.94 ? 304 VAL C CG1 1 
ATOM 7833  C CG2 . VAL C 1 304 ? -22.362 -64.028 16.034  1.00 111.33 ? 304 VAL C CG2 1 
ATOM 7834  N N   . GLN C 1 305 ? -23.138 -66.406 12.121  1.00 108.10 ? 305 GLN C N   1 
ATOM 7835  C CA  . GLN C 1 305 ? -22.317 -67.321 11.275  1.00 103.16 ? 305 GLN C CA  1 
ATOM 7836  C C   . GLN C 1 305 ? -22.076 -68.682 11.938  1.00 103.68 ? 305 GLN C C   1 
ATOM 7837  O O   . GLN C 1 305 ? -21.693 -69.613 11.208  1.00 98.13  ? 305 GLN C O   1 
ATOM 7838  C CB  . GLN C 1 305 ? -21.045 -66.628 10.776  1.00 102.31 ? 305 GLN C CB  1 
ATOM 7839  C CG  . GLN C 1 305 ? -21.273 -65.488 9.791   1.00 104.38 ? 305 GLN C CG  1 
ATOM 7840  C CD  . GLN C 1 305 ? -19.988 -64.803 9.395   1.00 110.63 ? 305 GLN C CD  1 
ATOM 7841  O OE1 . GLN C 1 305 ? -19.000 -64.820 10.126  1.00 116.02 ? 305 GLN C OE1 1 
ATOM 7842  N NE2 . GLN C 1 305 ? -19.993 -64.188 8.225   1.00 103.39 ? 305 GLN C NE2 1 
ATOM 7843  N N   . ARG C 1 306 ? -22.343 -68.828 13.238  1.00 106.61 ? 306 ARG C N   1 
ATOM 7844  C CA  . ARG C 1 306 ? -22.003 -70.091 13.938  1.00 101.25 ? 306 ARG C CA  1 
ATOM 7845  C C   . ARG C 1 306 ? -23.267 -70.786 14.432  1.00 100.83 ? 306 ARG C C   1 
ATOM 7846  O O   . ARG C 1 306 ? -23.171 -71.956 14.817  1.00 99.86  ? 306 ARG C O   1 
ATOM 7847  C CB  . ARG C 1 306 ? -21.053 -69.797 15.101  1.00 102.04 ? 306 ARG C CB  1 
ATOM 7848  C CG  . ARG C 1 306 ? -19.668 -69.332 14.675  1.00 105.79 ? 306 ARG C CG  1 
ATOM 7849  C CD  . ARG C 1 306 ? -18.983 -70.304 13.733  1.00 105.44 ? 306 ARG C CD  1 
ATOM 7850  N NE  . ARG C 1 306 ? -17.826 -69.719 13.069  1.00 94.65  ? 306 ARG C NE  1 
ATOM 7851  C CZ  . ARG C 1 306 ? -17.285 -70.184 11.949  1.00 101.41 ? 306 ARG C CZ  1 
ATOM 7852  N NH1 . ARG C 1 306 ? -17.797 -71.250 11.358  1.00 110.07 ? 306 ARG C NH1 1 
ATOM 7853  N NH2 . ARG C 1 306 ? -16.232 -69.584 11.422  1.00 107.83 ? 306 ARG C NH2 1 
ATOM 7854  N N   . VAL C 1 307 ? -24.406 -70.084 14.425  1.00 99.80  ? 307 VAL C N   1 
ATOM 7855  C CA  . VAL C 1 307 ? -25.708 -70.715 14.799  1.00 97.06  ? 307 VAL C CA  1 
ATOM 7856  C C   . VAL C 1 307 ? -26.611 -70.682 13.561  1.00 108.83 ? 307 VAL C C   1 
ATOM 7857  O O   . VAL C 1 307 ? -27.804 -71.022 13.688  1.00 108.56 ? 307 VAL C O   1 
ATOM 7858  C CB  . VAL C 1 307 ? -26.370 -70.019 16.005  1.00 95.58  ? 307 VAL C CB  1 
ATOM 7859  C CG1 . VAL C 1 307 ? -27.748 -70.589 16.302  1.00 97.71  ? 307 VAL C CG1 1 
ATOM 7860  C CG2 . VAL C 1 307 ? -25.497 -70.081 17.249  1.00 105.59 ? 307 VAL C CG2 1 
ATOM 7861  N N   . GLY C 1 308 ? -25.998 -70.563 12.380  1.00 110.73 ? 308 GLY C N   1 
ATOM 7862  C CA  . GLY C 1 308 ? -26.781 -70.635 11.133  1.00 106.09 ? 308 GLY C CA  1 
ATOM 7863  C C   . GLY C 1 308 ? -27.349 -72.028 10.972  1.00 109.74 ? 308 GLY C C   1 
ATOM 7864  O O   . GLY C 1 308 ? -26.551 -72.975 11.031  1.00 105.29 ? 308 GLY C O   1 
ATOM 7865  N N   . ASP C 1 309 ? -28.674 -72.154 10.810  1.00 117.86 ? 309 ASP C N   1 
ATOM 7866  C CA  . ASP C 1 309 ? -29.339 -73.480 10.683  1.00 113.84 ? 309 ASP C CA  1 
ATOM 7867  C C   . ASP C 1 309 ? -28.893 -74.136 9.385   1.00 108.34 ? 309 ASP C C   1 
ATOM 7868  O O   . ASP C 1 309 ? -29.662 -74.087 8.418   1.00 100.12 ? 309 ASP C O   1 
ATOM 7869  C CB  . ASP C 1 309 ? -30.864 -73.377 10.717  1.00 105.58 ? 309 ASP C CB  1 
ATOM 7870  C CG  . ASP C 1 309 ? -31.554 -74.682 11.069  1.00 109.30 ? 309 ASP C CG  1 
ATOM 7871  O OD1 . ASP C 1 309 ? -31.661 -74.981 12.273  1.00 118.87 ? 309 ASP C OD1 1 
ATOM 7872  O OD2 . ASP C 1 309 ? -31.983 -75.388 10.139  1.00 103.49 ? 309 ASP C OD2 1 
ATOM 7873  N N   . ARG C 1 310 ? -27.685 -74.693 9.372   1.00 109.27 ? 310 ARG C N   1 
ATOM 7874  C CA  . ARG C 1 310 ? -27.181 -75.415 8.181   1.00 104.87 ? 310 ARG C CA  1 
ATOM 7875  C C   . ARG C 1 310 ? -27.156 -74.480 6.974   1.00 100.59 ? 310 ARG C C   1 
ATOM 7876  O O   . ARG C 1 310 ? -28.005 -74.633 6.091   1.00 94.40  ? 310 ARG C O   1 
ATOM 7877  C CB  . ARG C 1 310 ? -27.990 -76.697 7.993   1.00 102.06 ? 310 ARG C CB  1 
ATOM 7878  C CG  . ARG C 1 310 ? -27.842 -77.691 9.137   1.00 104.05 ? 310 ARG C CG  1 
ATOM 7879  C CD  . ARG C 1 310 ? -26.392 -78.057 9.392   1.00 105.70 ? 310 ARG C CD  1 
ATOM 7880  N NE  . ARG C 1 310 ? -25.836 -77.399 10.565  1.00 102.97 ? 310 ARG C NE  1 
ATOM 7881  C CZ  . ARG C 1 310 ? -24.766 -76.613 10.550  1.00 101.79 ? 310 ARG C CZ  1 
ATOM 7882  N NH1 . ARG C 1 310 ? -24.128 -76.381 9.415   1.00 95.21  ? 310 ARG C NH1 1 
ATOM 7883  N NH2 . ARG C 1 310 ? -24.336 -76.059 11.668  1.00 105.86 ? 310 ARG C NH2 1 
ATOM 7884  N N   . GLY C 1 311 ? -26.195 -73.555 6.952   1.00 94.98  ? 311 GLY C N   1 
ATOM 7885  C CA  . GLY C 1 311 ? -26.052 -72.631 5.815   1.00 87.90  ? 311 GLY C CA  1 
ATOM 7886  C C   . GLY C 1 311 ? -24.601 -72.313 5.526   1.00 89.90  ? 311 GLY C C   1 
ATOM 7887  O O   . GLY C 1 311 ? -23.745 -72.744 6.310   1.00 95.33  ? 311 GLY C O   1 
ATOM 7888  N N   . LEU C 1 312 ? -24.338 -71.580 4.443   1.00 87.99  ? 312 LEU C N   1 
ATOM 7889  C CA  . LEU C 1 312 ? -22.953 -71.185 4.083   1.00 86.77  ? 312 LEU C CA  1 
ATOM 7890  C C   . LEU C 1 312 ? -22.968 -69.785 3.469   1.00 90.95  ? 312 LEU C C   1 
ATOM 7891  O O   . LEU C 1 312 ? -23.640 -69.604 2.453   1.00 92.34  ? 312 LEU C O   1 
ATOM 7892  C CB  . LEU C 1 312 ? -22.395 -72.210 3.094   1.00 88.93  ? 312 LEU C CB  1 
ATOM 7893  C CG  . LEU C 1 312 ? -20.952 -72.001 2.639   1.00 101.85 ? 312 LEU C CG  1 
ATOM 7894  C CD1 . LEU C 1 312 ? -20.043 -71.702 3.819   1.00 102.82 ? 312 LEU C CD1 1 
ATOM 7895  C CD2 . LEU C 1 312 ? -20.452 -73.221 1.885   1.00 107.62 ? 312 LEU C CD2 1 
ATOM 7896  N N   . VAL C 1 313 ? -22.240 -68.842 4.066   1.00 89.91  ? 313 VAL C N   1 
ATOM 7897  C CA  . VAL C 1 313 ? -22.157 -67.492 3.518   1.00 86.78  ? 313 VAL C CA  1 
ATOM 7898  C C   . VAL C 1 313 ? -20.878 -67.369 2.705   1.00 86.55  ? 313 VAL C C   1 
ATOM 7899  O O   . VAL C 1 313 ? -19.822 -67.886 3.095   1.00 94.57  ? 313 VAL C O   1 
ATOM 7900  C CB  . VAL C 1 313 ? -22.215 -66.428 4.632   1.00 77.11  ? 313 VAL C CB  1 
ATOM 7901  C CG1 . VAL C 1 313 ? -23.589 -66.419 5.284   1.00 78.30  ? 313 VAL C CG1 1 
ATOM 7902  C CG2 . VAL C 1 313 ? -21.133 -66.677 5.672   1.00 81.84  ? 313 VAL C CG2 1 
ATOM 7903  N N   . VAL C 1 314 ? -20.970 -66.694 1.563   1.00 81.61  ? 314 VAL C N   1 
ATOM 7904  C CA  . VAL C 1 314 ? -19.846 -66.512 0.654   1.00 83.66  ? 314 VAL C CA  1 
ATOM 7905  C C   . VAL C 1 314 ? -19.640 -65.019 0.432   1.00 85.59  ? 314 VAL C C   1 
ATOM 7906  O O   . VAL C 1 314 ? -20.607 -64.249 0.399   1.00 85.16  ? 314 VAL C O   1 
ATOM 7907  C CB  . VAL C 1 314 ? -20.075 -67.238 -0.690  1.00 80.20  ? 314 VAL C CB  1 
ATOM 7908  C CG1 . VAL C 1 314 ? -18.787 -67.287 -1.501  1.00 79.49  ? 314 VAL C CG1 1 
ATOM 7909  C CG2 . VAL C 1 314 ? -20.616 -68.643 -0.453  1.00 72.83  ? 314 VAL C CG2 1 
ATOM 7910  N N   . GLU C 1 315 ? -18.380 -64.615 0.279   1.00 95.81  ? 315 GLU C N   1 
ATOM 7911  C CA  . GLU C 1 315 ? -18.043 -63.209 0.094   1.00 106.56 ? 315 GLU C CA  1 
ATOM 7912  C C   . GLU C 1 315 ? -18.380 -62.733 -1.312  1.00 107.73 ? 315 GLU C C   1 
ATOM 7913  O O   . GLU C 1 315 ? -19.324 -61.958 -1.504  1.00 100.57 ? 315 GLU C O   1 
ATOM 7914  C CB  . GLU C 1 315 ? -16.560 -62.970 0.386   1.00 114.85 ? 315 GLU C CB  1 
ATOM 7915  C CG  . GLU C 1 315 ? -16.104 -61.538 0.151   1.00 127.17 ? 315 GLU C CG  1 
ATOM 7916  C CD  . GLU C 1 315 ? -14.980 -61.440 -0.865  1.00 128.25 ? 315 GLU C CD  1 
ATOM 7917  O OE1 . GLU C 1 315 ? -14.332 -62.470 -1.139  1.00 126.87 ? 315 GLU C OE1 1 
ATOM 7918  O OE2 . GLU C 1 315 ? -14.748 -60.331 -1.393  1.00 137.32 ? 315 GLU C OE2 1 
ATOM 7919  N N   . GLY C 1 316 ? -17.619 -63.192 -2.303  1.00 109.77 ? 316 GLY C N   1 
ATOM 7920  C CA  . GLY C 1 316 ? -17.759 -62.696 -3.659  1.00 108.28 ? 316 GLY C CA  1 
ATOM 7921  C C   . GLY C 1 316 ? -18.578 -63.576 -4.580  1.00 96.76  ? 316 GLY C C   1 
ATOM 7922  O O   . GLY C 1 316 ? -19.729 -63.904 -4.276  1.00 99.15  ? 316 GLY C O   1 
ATOM 7923  N N   . TRP C 1 317 ? -17.994 -63.959 -5.712  1.00 106.54 ? 317 TRP C N   1 
ATOM 7924  C CA  . TRP C 1 317 ? -18.725 -64.711 -6.722  1.00 111.93 ? 317 TRP C CA  1 
ATOM 7925  C C   . TRP C 1 317 ? -19.061 -66.110 -6.218  1.00 107.30 ? 317 TRP C C   1 
ATOM 7926  O O   . TRP C 1 317 ? -18.244 -66.774 -5.575  1.00 102.48 ? 317 TRP C O   1 
ATOM 7927  C CB  . TRP C 1 317 ? -17.915 -64.798 -8.015  1.00 107.79 ? 317 TRP C CB  1 
ATOM 7928  C CG  . TRP C 1 317 ? -17.668 -63.468 -8.668  1.00 115.48 ? 317 TRP C CG  1 
ATOM 7929  C CD1 . TRP C 1 317 ? -18.609 -62.595 -9.134  1.00 118.18 ? 317 TRP C CD1 1 
ATOM 7930  C CD2 . TRP C 1 317 ? -16.394 -62.864 -8.943  1.00 115.54 ? 317 TRP C CD2 1 
ATOM 7931  N NE1 . TRP C 1 317 ? -18.005 -61.486 -9.670  1.00 120.79 ? 317 TRP C NE1 1 
ATOM 7932  C CE2 . TRP C 1 317 ? -16.646 -61.626 -9.566  1.00 114.46 ? 317 TRP C CE2 1 
ATOM 7933  C CE3 . TRP C 1 317 ? -15.070 -63.251 -8.715  1.00 111.63 ? 317 TRP C CE3 1 
ATOM 7934  C CZ2 . TRP C 1 317 ? -15.621 -60.771 -9.967  1.00 114.51 ? 317 TRP C CZ2 1 
ATOM 7935  C CZ3 . TRP C 1 317 ? -14.053 -62.399 -9.116  1.00 111.62 ? 317 TRP C CZ3 1 
ATOM 7936  C CH2 . TRP C 1 317 ? -14.334 -61.174 -9.733  1.00 112.95 ? 317 TRP C CH2 1 
ATOM 7937  N N   . ALA C 1 318 ? -20.279 -66.555 -6.521  1.00 100.71 ? 318 ALA C N   1 
ATOM 7938  C CA  . ALA C 1 318 ? -20.785 -67.853 -6.119  1.00 100.86 ? 318 ALA C CA  1 
ATOM 7939  C C   . ALA C 1 318 ? -21.195 -68.663 -7.343  1.00 87.65  ? 318 ALA C C   1 
ATOM 7940  O O   . ALA C 1 318 ? -21.560 -68.090 -8.376  1.00 84.10  ? 318 ALA C O   1 
ATOM 7941  C CB  . ALA C 1 318 ? -21.986 -67.713 -5.175  1.00 98.86  ? 318 ALA C CB  1 
ATOM 7942  N N   . PRO C 1 319 ? -21.145 -69.995 -7.263  1.00 88.06  ? 319 PRO C N   1 
ATOM 7943  C CA  . PRO C 1 319 ? -21.565 -70.815 -8.405  1.00 85.29  ? 319 PRO C CA  1 
ATOM 7944  C C   . PRO C 1 319 ? -23.071 -70.772 -8.606  1.00 91.71  ? 319 PRO C C   1 
ATOM 7945  O O   . PRO C 1 319 ? -23.756 -71.772 -8.376  1.00 89.67  ? 319 PRO C O   1 
ATOM 7946  C CB  . PRO C 1 319 ? -21.095 -72.227 -8.025  1.00 88.99  ? 319 PRO C CB  1 
ATOM 7947  C CG  . PRO C 1 319 ? -20.192 -72.049 -6.844  1.00 100.46 ? 319 PRO C CG  1 
ATOM 7948  C CD  . PRO C 1 319 ? -20.643 -70.815 -6.152  1.00 99.37  ? 319 PRO C CD  1 
ATOM 7949  N N   . GLN C 1 320 ? -23.590 -69.620 -9.036  1.00 90.64  ? 320 GLN C N   1 
ATOM 7950  C CA  . GLN C 1 320 ? -25.035 -69.445 -9.150  1.00 83.92  ? 320 GLN C CA  1 
ATOM 7951  C C   . GLN C 1 320 ? -25.642 -70.481 -10.087 1.00 83.42  ? 320 GLN C C   1 
ATOM 7952  O O   . GLN C 1 320 ? -26.581 -71.197 -9.715  1.00 80.26  ? 320 GLN C O   1 
ATOM 7953  C CB  . GLN C 1 320 ? -25.349 -68.030 -9.632  1.00 85.28  ? 320 GLN C CB  1 
ATOM 7954  C CG  . GLN C 1 320 ? -26.815 -67.652 -9.553  1.00 80.85  ? 320 GLN C CG  1 
ATOM 7955  C CD  . GLN C 1 320 ? -27.074 -66.240 -10.035 1.00 85.52  ? 320 GLN C CD  1 
ATOM 7956  O OE1 . GLN C 1 320 ? -26.436 -65.766 -10.978 1.00 82.15  ? 320 GLN C OE1 1 
ATOM 7957  N NE2 . GLN C 1 320 ? -28.012 -65.554 -9.385  1.00 83.18  ? 320 GLN C NE2 1 
ATOM 7958  N N   . ALA C 1 321 ? -25.112 -70.579 -11.307 1.00 89.59  ? 321 ALA C N   1 
ATOM 7959  C CA  . ALA C 1 321 ? -25.622 -71.565 -12.254 1.00 85.30  ? 321 ALA C CA  1 
ATOM 7960  C C   . ALA C 1 321 ? -25.392 -72.984 -11.750 1.00 77.60  ? 321 ALA C C   1 
ATOM 7961  O O   . ALA C 1 321 ? -26.249 -73.860 -11.924 1.00 76.32  ? 321 ALA C O   1 
ATOM 7962  C CB  . ALA C 1 321 ? -24.969 -71.370 -13.621 1.00 78.76  ? 321 ALA C CB  1 
ATOM 7963  N N   . ARG C 1 322 ? -24.244 -73.231 -11.115 1.00 79.95  ? 322 ARG C N   1 
ATOM 7964  C CA  . ARG C 1 322 ? -23.921 -74.571 -10.633 1.00 86.88  ? 322 ARG C CA  1 
ATOM 7965  C C   . ARG C 1 322 ? -24.708 -74.940 -9.383  1.00 78.16  ? 322 ARG C C   1 
ATOM 7966  O O   . ARG C 1 322 ? -24.941 -76.127 -9.133  1.00 69.33  ? 322 ARG C O   1 
ATOM 7967  C CB  . ARG C 1 322 ? -22.418 -74.679 -10.366 1.00 91.33  ? 322 ARG C CB  1 
ATOM 7968  C CG  . ARG C 1 322 ? -21.558 -74.069 -11.468 1.00 96.59  ? 322 ARG C CG  1 
ATOM 7969  C CD  . ARG C 1 322 ? -20.072 -74.314 -11.243 1.00 105.11 ? 322 ARG C CD  1 
ATOM 7970  N NE  . ARG C 1 322 ? -19.600 -75.516 -11.920 1.00 108.58 ? 322 ARG C NE  1 
ATOM 7971  C CZ  . ARG C 1 322 ? -19.572 -76.726 -11.377 1.00 116.99 ? 322 ARG C CZ  1 
ATOM 7972  N NH1 . ARG C 1 322 ? -19.980 -76.938 -10.137 1.00 119.63 ? 322 ARG C NH1 1 
ATOM 7973  N NH2 . ARG C 1 322 ? -19.119 -77.751 -12.096 1.00 128.77 ? 322 ARG C NH2 1 
ATOM 7974  N N   . ILE C 1 323 ? -25.128 -73.951 -8.590  1.00 77.74  ? 323 ILE C N   1 
ATOM 7975  C CA  . ILE C 1 323 ? -25.966 -74.242 -7.434  1.00 74.87  ? 323 ILE C CA  1 
ATOM 7976  C C   . ILE C 1 323 ? -27.414 -74.452 -7.856  1.00 75.80  ? 323 ILE C C   1 
ATOM 7977  O O   . ILE C 1 323 ? -28.079 -75.387 -7.394  1.00 73.99  ? 323 ILE C O   1 
ATOM 7978  C CB  . ILE C 1 323 ? -25.839 -73.124 -6.381  1.00 80.29  ? 323 ILE C CB  1 
ATOM 7979  C CG1 . ILE C 1 323 ? -24.475 -73.194 -5.696  1.00 79.93  ? 323 ILE C CG1 1 
ATOM 7980  C CG2 . ILE C 1 323 ? -26.953 -73.220 -5.354  1.00 74.79  ? 323 ILE C CG2 1 
ATOM 7981  C CD1 . ILE C 1 323 ? -24.245 -72.085 -4.700  1.00 78.25  ? 323 ILE C CD1 1 
ATOM 7982  N N   . LEU C 1 324 ? -27.927 -73.592 -8.742  1.00 79.00  ? 324 LEU C N   1 
ATOM 7983  C CA  . LEU C 1 324 ? -29.285 -73.775 -9.238  1.00 71.25  ? 324 LEU C CA  1 
ATOM 7984  C C   . LEU C 1 324 ? -29.419 -75.062 -10.039 1.00 67.23  ? 324 LEU C C   1 
ATOM 7985  O O   . LEU C 1 324 ? -30.471 -75.710 -10.006 1.00 65.55  ? 324 LEU C O   1 
ATOM 7986  C CB  . LEU C 1 324 ? -29.705 -72.572 -10.083 1.00 67.19  ? 324 LEU C CB  1 
ATOM 7987  C CG  . LEU C 1 324 ? -29.824 -71.229 -9.359  1.00 61.61  ? 324 LEU C CG  1 
ATOM 7988  C CD1 . LEU C 1 324 ? -30.288 -70.150 -10.324 1.00 64.60  ? 324 LEU C CD1 1 
ATOM 7989  C CD2 . LEU C 1 324 ? -30.767 -71.336 -8.170  1.00 55.35  ? 324 LEU C CD2 1 
ATOM 7990  N N   . GLY C 1 325 ? -28.361 -75.458 -10.755 1.00 71.71  ? 325 GLY C N   1 
ATOM 7991  C CA  . GLY C 1 325 ? -28.391 -76.711 -11.486 1.00 68.70  ? 325 GLY C CA  1 
ATOM 7992  C C   . GLY C 1 325 ? -28.207 -77.940 -10.628 1.00 67.75  ? 325 GLY C C   1 
ATOM 7993  O O   . GLY C 1 325 ? -28.528 -79.046 -11.074 1.00 54.22  ? 325 GLY C O   1 
ATOM 7994  N N   . HIS C 1 326 ? -27.712 -77.777 -9.405  1.00 77.33  ? 326 HIS C N   1 
ATOM 7995  C CA  . HIS C 1 326 ? -27.541 -78.919 -8.518  1.00 72.26  ? 326 HIS C CA  1 
ATOM 7996  C C   . HIS C 1 326 ? -28.896 -79.405 -8.021  1.00 67.32  ? 326 HIS C C   1 
ATOM 7997  O O   . HIS C 1 326 ? -29.819 -78.615 -7.802  1.00 73.76  ? 326 HIS C O   1 
ATOM 7998  C CB  . HIS C 1 326 ? -26.634 -78.551 -7.342  1.00 74.62  ? 326 HIS C CB  1 
ATOM 7999  C CG  . HIS C 1 326 ? -26.137 -79.729 -6.567  1.00 75.09  ? 326 HIS C CG  1 
ATOM 8000  N ND1 . HIS C 1 326 ? -26.761 -80.180 -5.425  1.00 72.77  ? 326 HIS C ND1 1 
ATOM 8001  C CD2 . HIS C 1 326 ? -25.080 -80.549 -6.769  1.00 75.68  ? 326 HIS C CD2 1 
ATOM 8002  C CE1 . HIS C 1 326 ? -26.108 -81.228 -4.953  1.00 81.50  ? 326 HIS C CE1 1 
ATOM 8003  N NE2 . HIS C 1 326 ? -25.085 -81.473 -5.751  1.00 80.52  ? 326 HIS C NE2 1 
ATOM 8004  N N   . SER C 1 327 ? -29.014 -80.722 -7.844  1.00 76.08  ? 327 SER C N   1 
ATOM 8005  C CA  . SER C 1 327 ? -30.304 -81.311 -7.505  1.00 78.56  ? 327 SER C CA  1 
ATOM 8006  C C   . SER C 1 327 ? -30.734 -81.003 -6.076  1.00 77.83  ? 327 SER C C   1 
ATOM 8007  O O   . SER C 1 327 ? -31.917 -81.161 -5.754  1.00 81.75  ? 327 SER C O   1 
ATOM 8008  C CB  . SER C 1 327 ? -30.264 -82.823 -7.717  1.00 93.90  ? 327 SER C CB  1 
ATOM 8009  O OG  . SER C 1 327 ? -29.211 -83.416 -6.975  1.00 93.60  ? 327 SER C OG  1 
ATOM 8010  N N   . SER C 1 328 ? -29.812 -80.574 -5.214  1.00 81.21  ? 328 SER C N   1 
ATOM 8011  C CA  . SER C 1 328 ? -30.149 -80.296 -3.822  1.00 75.42  ? 328 SER C CA  1 
ATOM 8012  C C   . SER C 1 328 ? -30.824 -78.945 -3.628  1.00 71.10  ? 328 SER C C   1 
ATOM 8013  O O   . SER C 1 328 ? -31.329 -78.677 -2.532  1.00 70.70  ? 328 SER C O   1 
ATOM 8014  C CB  . SER C 1 328 ? -28.893 -80.368 -2.951  1.00 70.96  ? 328 SER C CB  1 
ATOM 8015  O OG  . SER C 1 328 ? -28.383 -81.687 -2.903  1.00 83.24  ? 328 SER C OG  1 
ATOM 8016  N N   . THR C 1 329 ? -30.847 -78.095 -4.649  1.00 73.52  ? 329 THR C N   1 
ATOM 8017  C CA  . THR C 1 329 ? -31.445 -76.776 -4.534  1.00 73.59  ? 329 THR C CA  1 
ATOM 8018  C C   . THR C 1 329 ? -32.907 -76.831 -4.958  1.00 70.90  ? 329 THR C C   1 
ATOM 8019  O O   . THR C 1 329 ? -33.237 -77.348 -6.032  1.00 64.63  ? 329 THR C O   1 
ATOM 8020  C CB  . THR C 1 329 ? -30.684 -75.758 -5.384  1.00 72.72  ? 329 THR C CB  1 
ATOM 8021  O OG1 . THR C 1 329 ? -29.279 -75.898 -5.147  1.00 81.76  ? 329 THR C OG1 1 
ATOM 8022  C CG2 . THR C 1 329 ? -31.108 -74.344 -5.023  1.00 68.39  ? 329 THR C CG2 1 
ATOM 8023  N N   . GLY C 1 330 ? -33.776 -76.305 -4.103  1.00 70.41  ? 330 GLY C N   1 
ATOM 8024  C CA  . GLY C 1 330 ? -35.195 -76.246 -4.384  1.00 64.21  ? 330 GLY C CA  1 
ATOM 8025  C C   . GLY C 1 330 ? -35.807 -74.893 -4.080  1.00 59.56  ? 330 GLY C C   1 
ATOM 8026  O O   . GLY C 1 330 ? -37.031 -74.770 -3.956  1.00 57.25  ? 330 GLY C O   1 
ATOM 8027  N N   . GLY C 1 331 ? -34.959 -73.869 -3.960  1.00 56.58  ? 331 GLY C N   1 
ATOM 8028  C CA  . GLY C 1 331 ? -35.399 -72.515 -3.676  1.00 56.90  ? 331 GLY C CA  1 
ATOM 8029  C C   . GLY C 1 331 ? -34.346 -71.473 -4.003  1.00 60.63  ? 331 GLY C C   1 
ATOM 8030  O O   . GLY C 1 331 ? -33.146 -71.717 -3.830  1.00 60.85  ? 331 GLY C O   1 
ATOM 8031  N N   . PHE C 1 332 ? -34.782 -70.305 -4.482  1.00 56.30  ? 332 PHE C N   1 
ATOM 8032  C CA  . PHE C 1 332 ? -33.860 -69.246 -4.905  1.00 51.35  ? 332 PHE C CA  1 
ATOM 8033  C C   . PHE C 1 332 ? -34.412 -67.905 -4.432  1.00 53.86  ? 332 PHE C C   1 
ATOM 8034  O O   . PHE C 1 332 ? -35.280 -67.322 -5.088  1.00 55.35  ? 332 PHE C O   1 
ATOM 8035  C CB  . PHE C 1 332 ? -33.662 -69.264 -6.420  1.00 51.84  ? 332 PHE C CB  1 
ATOM 8036  C CG  . PHE C 1 332 ? -32.657 -68.252 -6.940  1.00 50.37  ? 332 PHE C CG  1 
ATOM 8037  C CD1 . PHE C 1 332 ? -31.812 -67.553 -6.086  1.00 58.34  ? 332 PHE C CD1 1 
ATOM 8038  C CD2 . PHE C 1 332 ? -32.566 -68.001 -8.300  1.00 50.41  ? 332 PHE C CD2 1 
ATOM 8039  C CE1 . PHE C 1 332 ? -30.900 -66.621 -6.587  1.00 62.40  ? 332 PHE C CE1 1 
ATOM 8040  C CE2 . PHE C 1 332 ? -31.657 -67.073 -8.803  1.00 56.01  ? 332 PHE C CE2 1 
ATOM 8041  C CZ  . PHE C 1 332 ? -30.825 -66.387 -7.948  1.00 59.39  ? 332 PHE C CZ  1 
ATOM 8042  N N   . VAL C 1 333 ? -33.895 -67.412 -3.311  1.00 52.69  ? 333 VAL C N   1 
ATOM 8043  C CA  . VAL C 1 333 ? -34.223 -66.073 -2.829  1.00 56.22  ? 333 VAL C CA  1 
ATOM 8044  C C   . VAL C 1 333 ? -33.415 -65.078 -3.657  1.00 58.93  ? 333 VAL C C   1 
ATOM 8045  O O   . VAL C 1 333 ? -32.187 -65.024 -3.549  1.00 54.56  ? 333 VAL C O   1 
ATOM 8046  C CB  . VAL C 1 333 ? -33.927 -65.918 -1.334  1.00 56.09  ? 333 VAL C CB  1 
ATOM 8047  C CG1 . VAL C 1 333 ? -34.238 -64.500 -0.876  1.00 58.61  ? 333 VAL C CG1 1 
ATOM 8048  C CG2 . VAL C 1 333 ? -34.732 -66.924 -0.528  1.00 57.09  ? 333 VAL C CG2 1 
ATOM 8049  N N   . SER C 1 334 ? -34.097 -64.288 -4.482  1.00 61.10  ? 334 SER C N   1 
ATOM 8050  C CA  . SER C 1 334 ? -33.417 -63.458 -5.462  1.00 55.66  ? 334 SER C CA  1 
ATOM 8051  C C   . SER C 1 334 ? -33.979 -62.043 -5.459  1.00 56.63  ? 334 SER C C   1 
ATOM 8052  O O   . SER C 1 334 ? -35.116 -61.800 -5.049  1.00 61.23  ? 334 SER C O   1 
ATOM 8053  C CB  . SER C 1 334 ? -33.531 -64.056 -6.870  1.00 56.80  ? 334 SER C CB  1 
ATOM 8054  O OG  . SER C 1 334 ? -33.012 -63.167 -7.841  1.00 58.78  ? 334 SER C OG  1 
ATOM 8055  N N   . HIS C 1 335 ? -33.155 -61.108 -5.930  1.00 47.44  ? 335 HIS C N   1 
ATOM 8056  C CA  . HIS C 1 335 ? -33.592 -59.734 -6.146  1.00 53.22  ? 335 HIS C CA  1 
ATOM 8057  C C   . HIS C 1 335 ? -34.317 -59.557 -7.471  1.00 57.25  ? 335 HIS C C   1 
ATOM 8058  O O   . HIS C 1 335 ? -34.659 -58.422 -7.821  1.00 57.15  ? 335 HIS C O   1 
ATOM 8059  C CB  . HIS C 1 335 ? -32.395 -58.780 -6.078  1.00 57.77  ? 335 HIS C CB  1 
ATOM 8060  C CG  . HIS C 1 335 ? -31.509 -58.827 -7.287  1.00 65.24  ? 335 HIS C CG  1 
ATOM 8061  N ND1 . HIS C 1 335 ? -30.799 -59.953 -7.646  1.00 63.94  ? 335 HIS C ND1 1 
ATOM 8062  C CD2 . HIS C 1 335 ? -31.211 -57.882 -8.210  1.00 65.60  ? 335 HIS C CD2 1 
ATOM 8063  C CE1 . HIS C 1 335 ? -30.108 -59.701 -8.745  1.00 58.28  ? 335 HIS C CE1 1 
ATOM 8064  N NE2 . HIS C 1 335 ? -30.338 -58.452 -9.107  1.00 60.80  ? 335 HIS C NE2 1 
ATOM 8065  N N   . CYS C 1 336 ? -34.543 -60.648 -8.209  1.00 51.95  ? 336 CYS C N   1 
ATOM 8066  C CA  . CYS C 1 336 ? -35.348 -60.654 -9.434  1.00 47.41  ? 336 CYS C CA  1 
ATOM 8067  C C   . CYS C 1 336 ? -34.671 -59.883 -10.569 1.00 49.09  ? 336 CYS C C   1 
ATOM 8068  O O   . CYS C 1 336 ? -35.285 -59.057 -11.240 1.00 43.67  ? 336 CYS C O   1 
ATOM 8069  C CB  . CYS C 1 336 ? -36.760 -60.122 -9.175  1.00 47.76  ? 336 CYS C CB  1 
ATOM 8070  S SG  . CYS C 1 336 ? -37.758 -61.215 -8.162  1.00 49.79  ? 336 CYS C SG  1 
ATOM 8071  N N   . GLY C 1 337 ? -33.389 -60.165 -10.776 1.00 50.24  ? 337 GLY C N   1 
ATOM 8072  C CA  . GLY C 1 337 ? -32.759 -59.795 -12.027 1.00 48.20  ? 337 GLY C CA  1 
ATOM 8073  C C   . GLY C 1 337 ? -33.224 -60.704 -13.149 1.00 53.60  ? 337 GLY C C   1 
ATOM 8074  O O   . GLY C 1 337 ? -33.584 -61.862 -12.934 1.00 48.68  ? 337 GLY C O   1 
ATOM 8075  N N   . TRP C 1 338 ? -33.229 -60.168 -14.369 1.00 46.37  ? 338 TRP C N   1 
ATOM 8076  C CA  . TRP C 1 338 ? -33.765 -60.933 -15.492 1.00 38.55  ? 338 TRP C CA  1 
ATOM 8077  C C   . TRP C 1 338 ? -32.937 -62.183 -15.751 1.00 42.77  ? 338 TRP C C   1 
ATOM 8078  O O   . TRP C 1 338 ? -33.484 -63.277 -15.938 1.00 47.52  ? 338 TRP C O   1 
ATOM 8079  C CB  . TRP C 1 338 ? -33.844 -60.059 -16.742 1.00 34.66  ? 338 TRP C CB  1 
ATOM 8080  C CG  . TRP C 1 338 ? -34.588 -60.714 -17.868 1.00 33.72  ? 338 TRP C CG  1 
ATOM 8081  C CD1 . TRP C 1 338 ? -34.129 -60.935 -19.133 1.00 42.86  ? 338 TRP C CD1 1 
ATOM 8082  C CD2 . TRP C 1 338 ? -35.920 -61.248 -17.828 1.00 39.95  ? 338 TRP C CD2 1 
ATOM 8083  N NE1 . TRP C 1 338 ? -35.092 -61.559 -19.885 1.00 47.67  ? 338 TRP C NE1 1 
ATOM 8084  C CE2 . TRP C 1 338 ? -36.201 -61.764 -19.108 1.00 41.81  ? 338 TRP C CE2 1 
ATOM 8085  C CE3 . TRP C 1 338 ? -36.901 -61.332 -16.832 1.00 43.14  ? 338 TRP C CE3 1 
ATOM 8086  C CZ2 . TRP C 1 338 ? -37.423 -62.358 -19.419 1.00 40.39  ? 338 TRP C CZ2 1 
ATOM 8087  C CZ3 . TRP C 1 338 ? -38.110 -61.923 -17.145 1.00 41.22  ? 338 TRP C CZ3 1 
ATOM 8088  C CH2 . TRP C 1 338 ? -38.361 -62.428 -18.426 1.00 37.60  ? 338 TRP C CH2 1 
ATOM 8089  N N   . SER C 1 339 ? -31.608 -62.049 -15.770 1.00 53.79  ? 339 SER C N   1 
ATOM 8090  C CA  . SER C 1 339 ? -30.763 -63.228 -15.946 1.00 55.61  ? 339 SER C CA  1 
ATOM 8091  C C   . SER C 1 339 ? -30.911 -64.188 -14.773 1.00 50.86  ? 339 SER C C   1 
ATOM 8092  O O   . SER C 1 339 ? -30.870 -65.410 -14.953 1.00 48.43  ? 339 SER C O   1 
ATOM 8093  C CB  . SER C 1 339 ? -29.302 -62.811 -16.121 1.00 46.54  ? 339 SER C CB  1 
ATOM 8094  O OG  . SER C 1 339 ? -29.120 -62.094 -17.328 1.00 54.81  ? 339 SER C OG  1 
ATOM 8095  N N   . SER C 1 340 ? -31.105 -63.651 -13.568 1.00 53.72  ? 340 SER C N   1 
ATOM 8096  C CA  . SER C 1 340 ? -31.288 -64.503 -12.398 1.00 57.66  ? 340 SER C CA  1 
ATOM 8097  C C   . SER C 1 340 ? -32.567 -65.324 -12.510 1.00 58.64  ? 340 SER C C   1 
ATOM 8098  O O   . SER C 1 340 ? -32.567 -66.532 -12.246 1.00 62.86  ? 340 SER C O   1 
ATOM 8099  C CB  . SER C 1 340 ? -31.296 -63.651 -11.131 1.00 62.43  ? 340 SER C CB  1 
ATOM 8100  O OG  . SER C 1 340 ? -30.071 -62.953 -10.992 1.00 69.49  ? 340 SER C OG  1 
ATOM 8101  N N   . ILE C 1 341 ? -33.670 -64.686 -12.914 1.00 52.58  ? 341 ILE C N   1 
ATOM 8102  C CA  . ILE C 1 341 ? -34.932 -65.407 -13.065 1.00 51.41  ? 341 ILE C CA  1 
ATOM 8103  C C   . ILE C 1 341 ? -34.843 -66.416 -14.204 1.00 54.38  ? 341 ILE C C   1 
ATOM 8104  O O   . ILE C 1 341 ? -35.359 -67.537 -14.099 1.00 57.98  ? 341 ILE C O   1 
ATOM 8105  C CB  . ILE C 1 341 ? -36.086 -64.411 -13.270 1.00 52.40  ? 341 ILE C CB  1 
ATOM 8106  C CG1 . ILE C 1 341 ? -36.323 -63.614 -11.984 1.00 41.81  ? 341 ILE C CG1 1 
ATOM 8107  C CG2 . ILE C 1 341 ? -37.355 -65.134 -13.700 1.00 42.92  ? 341 ILE C CG2 1 
ATOM 8108  C CD1 . ILE C 1 341 ? -37.489 -62.656 -12.063 1.00 42.68  ? 341 ILE C CD1 1 
ATOM 8109  N N   . ALA C 1 342 ? -34.184 -66.044 -15.302 1.00 54.69  ? 342 ALA C N   1 
ATOM 8110  C CA  . ALA C 1 342 ? -34.007 -66.985 -16.404 1.00 58.43  ? 342 ALA C CA  1 
ATOM 8111  C C   . ALA C 1 342 ? -33.225 -68.215 -15.957 1.00 65.89  ? 342 ALA C C   1 
ATOM 8112  O O   . ALA C 1 342 ? -33.605 -69.348 -16.271 1.00 61.52  ? 342 ALA C O   1 
ATOM 8113  C CB  . ALA C 1 342 ? -33.311 -66.297 -17.579 1.00 55.87  ? 342 ALA C CB  1 
ATOM 8114  N N   . GLU C 1 343 ? -32.130 -68.010 -15.219 1.00 60.76  ? 343 GLU C N   1 
ATOM 8115  C CA  . GLU C 1 343 ? -31.354 -69.146 -14.726 1.00 63.90  ? 343 GLU C CA  1 
ATOM 8116  C C   . GLU C 1 343 ? -32.157 -69.982 -13.740 1.00 69.62  ? 343 GLU C C   1 
ATOM 8117  O O   . GLU C 1 343 ? -32.060 -71.214 -13.737 1.00 71.20  ? 343 GLU C O   1 
ATOM 8118  C CB  . GLU C 1 343 ? -30.058 -68.662 -14.076 1.00 67.09  ? 343 GLU C CB  1 
ATOM 8119  C CG  . GLU C 1 343 ? -28.986 -68.227 -15.050 1.00 67.50  ? 343 GLU C CG  1 
ATOM 8120  C CD  . GLU C 1 343 ? -27.660 -67.982 -14.362 1.00 84.80  ? 343 GLU C CD  1 
ATOM 8121  O OE1 . GLU C 1 343 ? -27.669 -67.742 -13.136 1.00 90.93  ? 343 GLU C OE1 1 
ATOM 8122  O OE2 . GLU C 1 343 ? -26.612 -68.042 -15.038 1.00 91.08  ? 343 GLU C OE2 1 
ATOM 8123  N N   . SER C 1 344 ? -32.950 -69.329 -12.887 1.00 67.49  ? 344 SER C N   1 
ATOM 8124  C CA  . SER C 1 344 ? -33.777 -70.071 -11.941 1.00 60.91  ? 344 SER C CA  1 
ATOM 8125  C C   . SER C 1 344 ? -34.824 -70.911 -12.657 1.00 62.45  ? 344 SER C C   1 
ATOM 8126  O O   . SER C 1 344 ? -35.184 -71.993 -12.178 1.00 63.19  ? 344 SER C O   1 
ATOM 8127  C CB  . SER C 1 344 ? -34.449 -69.115 -10.961 1.00 49.84  ? 344 SER C CB  1 
ATOM 8128  O OG  . SER C 1 344 ? -35.083 -69.826 -9.912  1.00 51.30  ? 344 SER C OG  1 
ATOM 8129  N N   . MET C 1 345 ? -35.324 -70.439 -13.795 1.00 58.58  ? 345 MET C N   1 
ATOM 8130  C CA  . MET C 1 345 ? -36.344 -71.191 -14.513 1.00 60.25  ? 345 MET C CA  1 
ATOM 8131  C C   . MET C 1 345 ? -35.765 -72.255 -15.437 1.00 68.06  ? 345 MET C C   1 
ATOM 8132  O O   . MET C 1 345 ? -36.445 -73.248 -15.720 1.00 68.50  ? 345 MET C O   1 
ATOM 8133  C CB  . MET C 1 345 ? -37.240 -70.239 -15.312 1.00 54.27  ? 345 MET C CB  1 
ATOM 8134  C CG  . MET C 1 345 ? -38.039 -69.298 -14.432 1.00 53.08  ? 345 MET C CG  1 
ATOM 8135  S SD  . MET C 1 345 ? -39.424 -68.562 -15.307 1.00 57.32  ? 345 MET C SD  1 
ATOM 8136  C CE  . MET C 1 345 ? -40.368 -70.031 -15.711 1.00 65.22  ? 345 MET C CE  1 
ATOM 8137  N N   . LYS C 1 346 ? -34.528 -72.084 -15.911 1.00 62.34  ? 346 LYS C N   1 
ATOM 8138  C CA  . LYS C 1 346 ? -33.923 -73.127 -16.732 1.00 61.43  ? 346 LYS C CA  1 
ATOM 8139  C C   . LYS C 1 346 ? -33.592 -74.373 -15.921 1.00 70.26  ? 346 LYS C C   1 
ATOM 8140  O O   . LYS C 1 346 ? -33.494 -75.463 -16.493 1.00 68.29  ? 346 LYS C O   1 
ATOM 8141  C CB  . LYS C 1 346 ? -32.659 -72.609 -17.424 1.00 62.89  ? 346 LYS C CB  1 
ATOM 8142  C CG  . LYS C 1 346 ? -32.156 -73.516 -18.546 1.00 60.19  ? 346 LYS C CG  1 
ATOM 8143  C CD  . LYS C 1 346 ? -30.703 -73.241 -18.891 1.00 70.52  ? 346 LYS C CD  1 
ATOM 8144  C CE  . LYS C 1 346 ? -30.210 -74.178 -19.984 1.00 81.20  ? 346 LYS C CE  1 
ATOM 8145  N NZ  . LYS C 1 346 ? -30.359 -75.609 -19.595 1.00 77.47  ? 346 LYS C NZ  1 
ATOM 8146  N N   . PHE C 1 347 ? -33.434 -74.242 -14.603 1.00 71.29  ? 347 PHE C N   1 
ATOM 8147  C CA  . PHE C 1 347 ? -33.114 -75.368 -13.740 1.00 73.90  ? 347 PHE C CA  1 
ATOM 8148  C C   . PHE C 1 347 ? -34.274 -75.762 -12.831 1.00 73.67  ? 347 PHE C C   1 
ATOM 8149  O O   . PHE C 1 347 ? -34.090 -76.593 -11.934 1.00 69.31  ? 347 PHE C O   1 
ATOM 8150  C CB  . PHE C 1 347 ? -31.867 -75.055 -12.908 1.00 67.46  ? 347 PHE C CB  1 
ATOM 8151  C CG  . PHE C 1 347 ? -30.640 -74.793 -13.736 1.00 71.97  ? 347 PHE C CG  1 
ATOM 8152  C CD1 . PHE C 1 347 ? -30.042 -75.815 -14.456 1.00 74.01  ? 347 PHE C CD1 1 
ATOM 8153  C CD2 . PHE C 1 347 ? -30.081 -73.528 -13.789 1.00 69.75  ? 347 PHE C CD2 1 
ATOM 8154  C CE1 . PHE C 1 347 ? -28.912 -75.576 -15.217 1.00 76.63  ? 347 PHE C CE1 1 
ATOM 8155  C CE2 . PHE C 1 347 ? -28.950 -73.284 -14.550 1.00 74.87  ? 347 PHE C CE2 1 
ATOM 8156  C CZ  . PHE C 1 347 ? -28.367 -74.310 -15.264 1.00 75.99  ? 347 PHE C CZ  1 
ATOM 8157  N N   . GLY C 1 348 ? -35.457 -75.188 -13.037 1.00 73.02  ? 348 GLY C N   1 
ATOM 8158  C CA  . GLY C 1 348 ? -36.632 -75.591 -12.284 1.00 60.43  ? 348 GLY C CA  1 
ATOM 8159  C C   . GLY C 1 348 ? -36.618 -75.236 -10.815 1.00 66.50  ? 348 GLY C C   1 
ATOM 8160  O O   . GLY C 1 348 ? -37.260 -75.924 -10.014 1.00 77.87  ? 348 GLY C O   1 
ATOM 8161  N N   . VAL C 1 349 ? -35.908 -74.183 -10.434 1.00 59.09  ? 349 VAL C N   1 
ATOM 8162  C CA  . VAL C 1 349 ? -35.826 -73.735 -9.048  1.00 55.04  ? 349 VAL C CA  1 
ATOM 8163  C C   . VAL C 1 349 ? -36.840 -72.613 -8.854  1.00 54.59  ? 349 VAL C C   1 
ATOM 8164  O O   . VAL C 1 349 ? -36.700 -71.556 -9.486  1.00 51.18  ? 349 VAL C O   1 
ATOM 8165  C CB  . VAL C 1 349 ? -34.407 -73.263 -8.694  1.00 63.94  ? 349 VAL C CB  1 
ATOM 8166  C CG1 . VAL C 1 349 ? -34.348 -72.777 -7.254  1.00 58.96  ? 349 VAL C CG1 1 
ATOM 8167  C CG2 . VAL C 1 349 ? -33.399 -74.379 -8.933  1.00 74.72  ? 349 VAL C CG2 1 
ATOM 8168  N N   . PRO C 1 350 ? -37.858 -72.790 -8.009  1.00 57.32  ? 350 PRO C N   1 
ATOM 8169  C CA  . PRO C 1 350 ? -38.828 -71.710 -7.787  1.00 55.24  ? 350 PRO C CA  1 
ATOM 8170  C C   . PRO C 1 350 ? -38.180 -70.494 -7.141  1.00 57.23  ? 350 PRO C C   1 
ATOM 8171  O O   . PRO C 1 350 ? -37.108 -70.571 -6.540  1.00 64.26  ? 350 PRO C O   1 
ATOM 8172  C CB  . PRO C 1 350 ? -39.870 -72.349 -6.861  1.00 48.90  ? 350 PRO C CB  1 
ATOM 8173  C CG  . PRO C 1 350 ? -39.159 -73.488 -6.216  1.00 51.17  ? 350 PRO C CG  1 
ATOM 8174  C CD  . PRO C 1 350 ? -38.196 -74.002 -7.246  1.00 56.92  ? 350 PRO C CD  1 
ATOM 8175  N N   . VAL C 1 351 ? -38.855 -69.354 -7.271  1.00 44.97  ? 351 VAL C N   1 
ATOM 8176  C CA  . VAL C 1 351 ? -38.271 -68.049 -6.975  1.00 47.63  ? 351 VAL C CA  1 
ATOM 8177  C C   . VAL C 1 351 ? -38.931 -67.455 -5.737  1.00 54.73  ? 351 VAL C C   1 
ATOM 8178  O O   . VAL C 1 351 ? -40.161 -67.476 -5.603  1.00 58.52  ? 351 VAL C O   1 
ATOM 8179  C CB  . VAL C 1 351 ? -38.406 -67.094 -8.171  1.00 44.52  ? 351 VAL C CB  1 
ATOM 8180  C CG1 . VAL C 1 351 ? -37.701 -65.777 -7.881  1.00 48.97  ? 351 VAL C CG1 1 
ATOM 8181  C CG2 . VAL C 1 351 ? -37.849 -67.738 -9.431  1.00 48.29  ? 351 VAL C CG2 1 
ATOM 8182  N N   . ILE C 1 352 ? -38.105 -66.931 -4.836  1.00 54.88  ? 352 ILE C N   1 
ATOM 8183  C CA  . ILE C 1 352 ? -38.544 -66.115 -3.712  1.00 57.52  ? 352 ILE C CA  1 
ATOM 8184  C C   . ILE C 1 352 ? -38.195 -64.679 -4.085  1.00 56.31  ? 352 ILE C C   1 
ATOM 8185  O O   . ILE C 1 352 ? -37.024 -64.279 -4.051  1.00 54.72  ? 352 ILE C O   1 
ATOM 8186  C CB  . ILE C 1 352 ? -37.871 -66.542 -2.404  1.00 61.60  ? 352 ILE C CB  1 
ATOM 8187  C CG1 . ILE C 1 352 ? -37.857 -68.065 -2.275  1.00 54.98  ? 352 ILE C CG1 1 
ATOM 8188  C CG2 . ILE C 1 352 ? -38.569 -65.907 -1.212  1.00 52.72  ? 352 ILE C CG2 1 
ATOM 8189  C CD1 . ILE C 1 352 ? -39.228 -68.676 -2.174  1.00 56.25  ? 352 ILE C CD1 1 
ATOM 8190  N N   . ALA C 1 353 ? -39.208 -63.902 -4.452  1.00 48.69  ? 353 ALA C N   1 
ATOM 8191  C CA  . ALA C 1 353 ? -38.995 -62.563 -4.976  1.00 55.61  ? 353 ALA C CA  1 
ATOM 8192  C C   . ALA C 1 353 ? -38.748 -61.577 -3.845  1.00 54.97  ? 353 ALA C C   1 
ATOM 8193  O O   . ALA C 1 353 ? -39.554 -61.462 -2.914  1.00 60.94  ? 353 ALA C O   1 
ATOM 8194  C CB  . ALA C 1 353 ? -40.195 -62.120 -5.812  1.00 49.28  ? 353 ALA C CB  1 
ATOM 8195  N N   . MET C 1 354 ? -37.620 -60.856 -3.928  1.00 57.40  ? 354 MET C N   1 
ATOM 8196  C CA  . MET C 1 354 ? -37.267 -59.805 -2.983  1.00 66.06  ? 354 MET C CA  1 
ATOM 8197  C C   . MET C 1 354 ? -36.649 -58.653 -3.785  1.00 67.83  ? 354 MET C C   1 
ATOM 8198  O O   . MET C 1 354 ? -35.464 -58.343 -3.679  1.00 66.48  ? 354 MET C O   1 
ATOM 8199  C CB  . MET C 1 354 ? -36.319 -60.315 -1.895  1.00 61.64  ? 354 MET C CB  1 
ATOM 8200  C CG  . MET C 1 354 ? -36.979 -61.256 -0.894  1.00 74.98  ? 354 MET C CG  1 
ATOM 8201  S SD  . MET C 1 354 ? -35.922 -61.705 0.498   1.00 74.88  ? 354 MET C SD  1 
ATOM 8202  C CE  . MET C 1 354 ? -35.389 -60.088 1.057   1.00 60.15  ? 354 MET C CE  1 
ATOM 8203  N N   . ALA C 1 355 ? -37.471 -58.011 -4.610  1.00 58.11  ? 355 ALA C N   1 
ATOM 8204  C CA  . ALA C 1 355 ? -37.023 -56.914 -5.449  1.00 66.93  ? 355 ALA C CA  1 
ATOM 8205  C C   . ALA C 1 355 ? -37.015 -55.604 -4.664  1.00 66.95  ? 355 ALA C C   1 
ATOM 8206  O O   . ALA C 1 355 ? -37.500 -55.523 -3.532  1.00 69.43  ? 355 ALA C O   1 
ATOM 8207  C CB  . ALA C 1 355 ? -37.916 -56.789 -6.680  1.00 66.28  ? 355 ALA C CB  1 
ATOM 8208  N N   . ARG C 1 356 ? -36.451 -54.564 -5.280  1.00 73.11  ? 356 ARG C N   1 
ATOM 8209  C CA  . ARG C 1 356 ? -36.427 -53.255 -4.633  1.00 82.58  ? 356 ARG C CA  1 
ATOM 8210  C C   . ARG C 1 356 ? -36.456 -52.110 -5.640  1.00 72.31  ? 356 ARG C C   1 
ATOM 8211  O O   . ARG C 1 356 ? -37.285 -51.201 -5.520  1.00 78.37  ? 356 ARG C O   1 
ATOM 8212  C CB  . ARG C 1 356 ? -35.199 -53.126 -3.727  1.00 88.71  ? 356 ARG C CB  1 
ATOM 8213  C CG  . ARG C 1 356 ? -35.524 -52.542 -2.357  1.00 93.05  ? 356 ARG C CG  1 
ATOM 8214  C CD  . ARG C 1 356 ? -34.275 -52.286 -1.525  1.00 101.31 ? 356 ARG C CD  1 
ATOM 8215  N NE  . ARG C 1 356 ? -33.592 -51.060 -1.925  1.00 114.65 ? 356 ARG C NE  1 
ATOM 8216  C CZ  . ARG C 1 356 ? -33.918 -49.847 -1.493  1.00 113.53 ? 356 ARG C CZ  1 
ATOM 8217  N NH1 . ARG C 1 356 ? -34.925 -49.660 -0.656  1.00 110.66 ? 356 ARG C NH1 1 
ATOM 8218  N NH2 . ARG C 1 356 ? -33.218 -48.798 -1.912  1.00 107.02 ? 356 ARG C NH2 1 
ATOM 8219  N N   . HIS C 1 357 ? -35.563 -52.130 -6.627  1.00 67.77  ? 357 HIS C N   1 
ATOM 8220  C CA  . HIS C 1 357 ? -35.418 -51.018 -7.554  1.00 74.62  ? 357 HIS C CA  1 
ATOM 8221  C C   . HIS C 1 357 ? -35.374 -51.530 -8.990  1.00 67.52  ? 357 HIS C C   1 
ATOM 8222  O O   . HIS C 1 357 ? -35.332 -52.735 -9.246  1.00 61.74  ? 357 HIS C O   1 
ATOM 8223  C CB  . HIS C 1 357 ? -34.164 -50.190 -7.239  1.00 79.26  ? 357 HIS C CB  1 
ATOM 8224  C CG  . HIS C 1 357 ? -32.906 -50.998 -7.179  1.00 85.76  ? 357 HIS C CG  1 
ATOM 8225  N ND1 . HIS C 1 357 ? -32.073 -51.165 -8.265  1.00 89.15  ? 357 HIS C ND1 1 
ATOM 8226  C CD2 . HIS C 1 357 ? -32.334 -51.684 -6.159  1.00 85.52  ? 357 HIS C CD2 1 
ATOM 8227  C CE1 . HIS C 1 357 ? -31.046 -51.919 -7.920  1.00 91.13  ? 357 HIS C CE1 1 
ATOM 8228  N NE2 . HIS C 1 357 ? -31.181 -52.247 -6.647  1.00 94.93  ? 357 HIS C NE2 1 
ATOM 8229  N N   . LEU C 1 358 ? -35.389 -50.583 -9.926  1.00 75.31  ? 358 LEU C N   1 
ATOM 8230  C CA  . LEU C 1 358 ? -35.355 -50.850 -11.369 1.00 70.57  ? 358 LEU C CA  1 
ATOM 8231  C C   . LEU C 1 358 ? -36.589 -51.677 -11.742 1.00 61.52  ? 358 LEU C C   1 
ATOM 8232  O O   . LEU C 1 358 ? -37.635 -51.583 -11.089 1.00 66.67  ? 358 LEU C O   1 
ATOM 8233  C CB  . LEU C 1 358 ? -34.027 -51.485 -11.750 1.00 71.77  ? 358 LEU C CB  1 
ATOM 8234  C CG  . LEU C 1 358 ? -32.786 -50.618 -11.534 1.00 75.10  ? 358 LEU C CG  1 
ATOM 8235  C CD1 . LEU C 1 358 ? -31.540 -51.299 -12.086 1.00 79.90  ? 358 LEU C CD1 1 
ATOM 8236  C CD2 . LEU C 1 358 ? -32.982 -49.251 -12.164 1.00 68.87  ? 358 LEU C CD2 1 
ATOM 8237  N N   . ASP C 1 359 ? -36.481 -52.485 -12.793 1.00 52.13  ? 359 ASP C N   1 
ATOM 8238  C CA  . ASP C 1 359 ? -37.572 -53.323 -13.269 1.00 57.26  ? 359 ASP C CA  1 
ATOM 8239  C C   . ASP C 1 359 ? -37.696 -54.629 -12.496 1.00 58.29  ? 359 ASP C C   1 
ATOM 8240  O O   . ASP C 1 359 ? -38.475 -55.498 -12.899 1.00 56.29  ? 359 ASP C O   1 
ATOM 8241  C CB  . ASP C 1 359 ? -37.384 -53.627 -14.756 1.00 58.82  ? 359 ASP C CB  1 
ATOM 8242  C CG  . ASP C 1 359 ? -36.135 -54.446 -15.026 1.00 69.10  ? 359 ASP C CG  1 
ATOM 8243  O OD1 . ASP C 1 359 ? -35.167 -54.336 -14.237 1.00 64.78  ? 359 ASP C OD1 1 
ATOM 8244  O OD2 . ASP C 1 359 ? -36.123 -55.207 -16.019 1.00 64.75  ? 359 ASP C OD2 1 
ATOM 8245  N N   . GLN C 1 360 ? -36.946 -54.775 -11.408 1.00 59.18  ? 360 GLN C N   1 
ATOM 8246  C CA  . GLN C 1 360 ? -36.981 -56.018 -10.643 1.00 53.03  ? 360 GLN C CA  1 
ATOM 8247  C C   . GLN C 1 360 ? -38.354 -56.332 -10.055 1.00 55.90  ? 360 GLN C C   1 
ATOM 8248  O O   . GLN C 1 360 ? -38.737 -57.515 -10.074 1.00 52.71  ? 360 GLN C O   1 
ATOM 8249  C CB  . GLN C 1 360 ? -35.911 -55.971 -9.544  1.00 56.71  ? 360 GLN C CB  1 
ATOM 8250  C CG  . GLN C 1 360 ? -34.500 -55.739 -10.065 1.00 60.50  ? 360 GLN C CG  1 
ATOM 8251  C CD  . GLN C 1 360 ? -33.525 -55.378 -8.964  1.00 65.29  ? 360 GLN C CD  1 
ATOM 8252  O OE1 . GLN C 1 360 ? -33.808 -55.568 -7.779  1.00 71.91  ? 360 GLN C OE1 1 
ATOM 8253  N NE2 . GLN C 1 360 ? -32.370 -54.849 -9.347  1.00 68.70  ? 360 GLN C NE2 1 
ATOM 8254  N N   . PRO C 1 361 ? -39.119 -55.377 -9.509  1.00 56.09  ? 361 PRO C N   1 
ATOM 8255  C CA  . PRO C 1 361 ? -40.487 -55.731 -9.084  1.00 56.90  ? 361 PRO C CA  1 
ATOM 8256  C C   . PRO C 1 361 ? -41.335 -56.280 -10.219 1.00 58.53  ? 361 PRO C C   1 
ATOM 8257  O O   . PRO C 1 361 ? -41.943 -57.350 -10.069 1.00 59.43  ? 361 PRO C O   1 
ATOM 8258  C CB  . PRO C 1 361 ? -41.029 -54.404 -8.536  1.00 55.70  ? 361 PRO C CB  1 
ATOM 8259  C CG  . PRO C 1 361 ? -39.826 -53.673 -8.082  1.00 51.94  ? 361 PRO C CG  1 
ATOM 8260  C CD  . PRO C 1 361 ? -38.765 -54.007 -9.091  1.00 54.85  ? 361 PRO C CD  1 
ATOM 8261  N N   . LEU C 1 362 ? -41.372 -55.588 -11.364 1.00 48.44  ? 362 LEU C N   1 
ATOM 8262  C CA  . LEU C 1 362 ? -42.148 -56.075 -12.503 1.00 41.12  ? 362 LEU C CA  1 
ATOM 8263  C C   . LEU C 1 362 ? -41.741 -57.492 -12.884 1.00 43.50  ? 362 LEU C C   1 
ATOM 8264  O O   . LEU C 1 362 ? -42.596 -58.320 -13.217 1.00 50.72  ? 362 LEU C O   1 
ATOM 8265  C CB  . LEU C 1 362 ? -41.989 -55.139 -13.704 1.00 51.38  ? 362 LEU C CB  1 
ATOM 8266  C CG  . LEU C 1 362 ? -42.521 -53.707 -13.608 1.00 45.36  ? 362 LEU C CG  1 
ATOM 8267  C CD1 . LEU C 1 362 ? -43.875 -53.664 -12.912 1.00 42.67  ? 362 LEU C CD1 1 
ATOM 8268  C CD2 . LEU C 1 362 ? -41.515 -52.781 -12.927 1.00 59.41  ? 362 LEU C CD2 1 
ATOM 8269  N N   . ASN C 1 363 ? -40.441 -57.790 -12.844 1.00 42.42  ? 363 ASN C N   1 
ATOM 8270  C CA  . ASN C 1 363 ? -39.996 -59.155 -13.108 1.00 43.09  ? 363 ASN C CA  1 
ATOM 8271  C C   . ASN C 1 363 ? -40.586 -60.120 -12.090 1.00 46.35  ? 363 ASN C C   1 
ATOM 8272  O O   . ASN C 1 363 ? -41.163 -61.151 -12.453 1.00 48.30  ? 363 ASN C O   1 
ATOM 8273  C CB  . ASN C 1 363 ? -38.467 -59.230 -13.095 1.00 48.07  ? 363 ASN C CB  1 
ATOM 8274  C CG  . ASN C 1 363 ? -37.825 -58.351 -14.154 1.00 52.63  ? 363 ASN C CG  1 
ATOM 8275  O OD1 . ASN C 1 363 ? -38.470 -57.946 -15.123 1.00 56.18  ? 363 ASN C OD1 1 
ATOM 8276  N ND2 . ASN C 1 363 ? -36.541 -58.060 -13.978 1.00 47.00  ? 363 ASN C ND2 1 
ATOM 8277  N N   . GLY C 1 364 ? -40.475 -59.779 -10.803 1.00 51.65  ? 364 GLY C N   1 
ATOM 8278  C CA  . GLY C 1 364 ? -40.928 -60.645 -9.730  1.00 39.76  ? 364 GLY C CA  1 
ATOM 8279  C C   . GLY C 1 364 ? -42.361 -61.098 -9.892  1.00 48.62  ? 364 GLY C C   1 
ATOM 8280  O O   . GLY C 1 364 ? -42.615 -62.290 -10.093 1.00 45.81  ? 364 GLY C O   1 
ATOM 8281  N N   . LYS C 1 365 ? -43.303 -60.149 -9.831  1.00 53.75  ? 365 LYS C N   1 
ATOM 8282  C CA  . LYS C 1 365 ? -44.706 -60.477 -10.068 1.00 58.55  ? 365 LYS C CA  1 
ATOM 8283  C C   . LYS C 1 365 ? -44.896 -61.220 -11.384 1.00 48.65  ? 365 LYS C C   1 
ATOM 8284  O O   . LYS C 1 365 ? -45.769 -62.093 -11.472 1.00 53.19  ? 365 LYS C O   1 
ATOM 8285  C CB  . LYS C 1 365 ? -45.566 -59.211 -10.043 1.00 55.29  ? 365 LYS C CB  1 
ATOM 8286  C CG  . LYS C 1 365 ? -45.192 -58.161 -11.082 1.00 50.01  ? 365 LYS C CG  1 
ATOM 8287  C CD  . LYS C 1 365 ? -45.888 -56.834 -10.788 1.00 57.68  ? 365 LYS C CD  1 
ATOM 8288  C CE  . LYS C 1 365 ? -47.398 -57.006 -10.685 1.00 65.70  ? 365 LYS C CE  1 
ATOM 8289  N NZ  . LYS C 1 365 ? -48.086 -55.723 -10.362 1.00 59.07  ? 365 LYS C NZ  1 
ATOM 8290  N N   . LEU C 1 366 ? -44.095 -60.903 -12.404 1.00 37.29  ? 366 LEU C N   1 
ATOM 8291  C CA  . LEU C 1 366 ? -44.142 -61.669 -13.646 1.00 46.05  ? 366 LEU C CA  1 
ATOM 8292  C C   . LEU C 1 366 ? -43.983 -63.160 -13.363 1.00 46.33  ? 366 LEU C C   1 
ATOM 8293  O O   . LEU C 1 366 ? -44.868 -63.964 -13.680 1.00 45.85  ? 366 LEU C O   1 
ATOM 8294  C CB  . LEU C 1 366 ? -43.061 -61.181 -14.610 1.00 48.82  ? 366 LEU C CB  1 
ATOM 8295  C CG  . LEU C 1 366 ? -43.023 -61.876 -15.973 1.00 40.64  ? 366 LEU C CG  1 
ATOM 8296  C CD1 . LEU C 1 366 ? -44.274 -61.586 -16.789 1.00 38.92  ? 366 LEU C CD1 1 
ATOM 8297  C CD2 . LEU C 1 366 ? -41.774 -61.461 -16.735 1.00 50.46  ? 366 LEU C CD2 1 
ATOM 8298  N N   . ALA C 1 367 ? -42.874 -63.544 -12.727 1.00 48.09  ? 367 ALA C N   1 
ATOM 8299  C CA  . ALA C 1 367 ? -42.699 -64.941 -12.338 1.00 50.93  ? 367 ALA C CA  1 
ATOM 8300  C C   . ALA C 1 367 ? -43.749 -65.397 -11.335 1.00 50.95  ? 367 ALA C C   1 
ATOM 8301  O O   . ALA C 1 367 ? -44.043 -66.595 -11.264 1.00 51.28  ? 367 ALA C O   1 
ATOM 8302  C CB  . ALA C 1 367 ? -41.291 -65.163 -11.787 1.00 50.10  ? 367 ALA C CB  1 
ATOM 8303  N N   . ALA C 1 368 ? -44.343 -64.471 -10.580 1.00 52.02  ? 368 ALA C N   1 
ATOM 8304  C CA  . ALA C 1 368 ? -45.464 -64.808 -9.712  1.00 46.33  ? 368 ALA C CA  1 
ATOM 8305  C C   . ALA C 1 368 ? -46.774 -64.922 -10.472 1.00 48.66  ? 368 ALA C C   1 
ATOM 8306  O O   . ALA C 1 368 ? -47.675 -65.642 -10.031 1.00 49.99  ? 368 ALA C O   1 
ATOM 8307  C CB  . ALA C 1 368 ? -45.608 -63.774 -8.597  1.00 56.43  ? 368 ALA C CB  1 
ATOM 8308  N N   . GLU C 1 369 ? -46.890 -64.242 -11.613 1.00 47.85  ? 369 GLU C N   1 
ATOM 8309  C CA  . GLU C 1 369 ? -48.097 -64.347 -12.425 1.00 46.11  ? 369 GLU C CA  1 
ATOM 8310  C C   . GLU C 1 369 ? -48.217 -65.728 -13.058 1.00 49.21  ? 369 GLU C C   1 
ATOM 8311  O O   . GLU C 1 369 ? -49.317 -66.293 -13.121 1.00 49.31  ? 369 GLU C O   1 
ATOM 8312  C CB  . GLU C 1 369 ? -48.097 -63.256 -13.496 1.00 52.09  ? 369 GLU C CB  1 
ATOM 8313  C CG  . GLU C 1 369 ? -49.089 -63.455 -14.627 1.00 55.92  ? 369 GLU C CG  1 
ATOM 8314  C CD  . GLU C 1 369 ? -49.011 -62.345 -15.663 1.00 57.27  ? 369 GLU C CD  1 
ATOM 8315  O OE1 . GLU C 1 369 ? -48.966 -61.161 -15.263 1.00 48.25  ? 369 GLU C OE1 1 
ATOM 8316  O OE2 . GLU C 1 369 ? -48.978 -62.654 -16.874 1.00 70.15  ? 369 GLU C OE2 1 
ATOM 8317  N N   . VAL C 1 370 ? -47.100 -66.292 -13.523 1.00 39.31  ? 370 VAL C N   1 
ATOM 8318  C CA  . VAL C 1 370 ? -47.124 -67.607 -14.162 1.00 41.37  ? 370 VAL C CA  1 
ATOM 8319  C C   . VAL C 1 370 ? -47.107 -68.753 -13.162 1.00 46.53  ? 370 VAL C C   1 
ATOM 8320  O O   . VAL C 1 370 ? -47.412 -69.892 -13.538 1.00 54.52  ? 370 VAL C O   1 
ATOM 8321  C CB  . VAL C 1 370 ? -45.944 -67.765 -15.138 1.00 48.74  ? 370 VAL C CB  1 
ATOM 8322  C CG1 . VAL C 1 370 ? -45.986 -66.673 -16.199 1.00 60.07  ? 370 VAL C CG1 1 
ATOM 8323  C CG2 . VAL C 1 370 ? -44.624 -67.731 -14.386 1.00 53.75  ? 370 VAL C CG2 1 
ATOM 8324  N N   . GLY C 1 371 ? -46.755 -68.487 -11.906 1.00 53.69  ? 371 GLY C N   1 
ATOM 8325  C CA  . GLY C 1 371 ? -46.858 -69.477 -10.854 1.00 53.09  ? 371 GLY C CA  1 
ATOM 8326  C C   . GLY C 1 371 ? -45.580 -70.195 -10.476 1.00 59.38  ? 371 GLY C C   1 
ATOM 8327  O O   . GLY C 1 371 ? -45.654 -71.214 -9.780  1.00 55.60  ? 371 GLY C O   1 
ATOM 8328  N N   . VAL C 1 372 ? -44.420 -69.707 -10.899 1.00 54.04  ? 372 VAL C N   1 
ATOM 8329  C CA  . VAL C 1 372 ? -43.150 -70.354 -10.588 1.00 48.72  ? 372 VAL C CA  1 
ATOM 8330  C C   . VAL C 1 372 ? -42.401 -69.616 -9.475  1.00 41.71  ? 372 VAL C C   1 
ATOM 8331  O O   . VAL C 1 372 ? -41.204 -69.830 -9.290  1.00 42.86  ? 372 VAL C O   1 
ATOM 8332  C CB  . VAL C 1 372 ? -42.272 -70.507 -11.840 1.00 50.00  ? 372 VAL C CB  1 
ATOM 8333  C CG1 . VAL C 1 372 ? -42.981 -71.354 -12.885 1.00 39.66  ? 372 VAL C CG1 1 
ATOM 8334  C CG2 . VAL C 1 372 ? -41.900 -69.144 -12.401 1.00 40.97  ? 372 VAL C CG2 1 
ATOM 8335  N N   . GLY C 1 373 ? -43.086 -68.754 -8.733  1.00 41.52  ? 373 GLY C N   1 
ATOM 8336  C CA  . GLY C 1 373 ? -42.439 -68.038 -7.652  1.00 49.06  ? 373 GLY C CA  1 
ATOM 8337  C C   . GLY C 1 373 ? -43.463 -67.326 -6.796  1.00 53.67  ? 373 GLY C C   1 
ATOM 8338  O O   . GLY C 1 373 ? -44.664 -67.345 -7.073  1.00 56.41  ? 373 GLY C O   1 
ATOM 8339  N N   . MET C 1 374 ? -42.961 -66.691 -5.737  1.00 52.30  ? 374 MET C N   1 
ATOM 8340  C CA  . MET C 1 374 ? -43.809 -65.933 -4.827  1.00 58.22  ? 374 MET C CA  1 
ATOM 8341  C C   . MET C 1 374 ? -43.017 -64.774 -4.240  1.00 59.60  ? 374 MET C C   1 
ATOM 8342  O O   . MET C 1 374 ? -41.843 -64.926 -3.899  1.00 57.39  ? 374 MET C O   1 
ATOM 8343  C CB  . MET C 1 374 ? -44.352 -66.807 -3.695  1.00 65.48  ? 374 MET C CB  1 
ATOM 8344  C CG  . MET C 1 374 ? -45.464 -66.139 -2.900  1.00 61.62  ? 374 MET C CG  1 
ATOM 8345  S SD  . MET C 1 374 ? -45.440 -66.544 -1.144  1.00 86.19  ? 374 MET C SD  1 
ATOM 8346  C CE  . MET C 1 374 ? -45.532 -68.331 -1.203  1.00 67.94  ? 374 MET C CE  1 
ATOM 8347  N N   . GLU C 1 375 ? -43.668 -63.621 -4.126  1.00 66.63  ? 375 GLU C N   1 
ATOM 8348  C CA  . GLU C 1 375 ? -43.043 -62.429 -3.575  1.00 58.52  ? 375 GLU C CA  1 
ATOM 8349  C C   . GLU C 1 375 ? -43.271 -62.349 -2.072  1.00 65.29  ? 375 GLU C C   1 
ATOM 8350  O O   . GLU C 1 375 ? -44.294 -62.809 -1.552  1.00 64.60  ? 375 GLU C O   1 
ATOM 8351  C CB  . GLU C 1 375 ? -43.595 -61.167 -4.240  1.00 57.95  ? 375 GLU C CB  1 
ATOM 8352  C CG  . GLU C 1 375 ? -44.053 -61.359 -5.669  1.00 61.82  ? 375 GLU C CG  1 
ATOM 8353  C CD  . GLU C 1 375 ? -44.542 -60.069 -6.295  1.00 70.64  ? 375 GLU C CD  1 
ATOM 8354  O OE1 . GLU C 1 375 ? -43.805 -59.061 -6.233  1.00 69.99  ? 375 GLU C OE1 1 
ATOM 8355  O OE2 . GLU C 1 375 ? -45.667 -60.059 -6.837  1.00 75.55  ? 375 GLU C OE2 1 
ATOM 8356  N N   . VAL C 1 376 ? -42.305 -61.754 -1.370  1.00 75.18  ? 376 VAL C N   1 
ATOM 8357  C CA  . VAL C 1 376 ? -42.483 -61.499 0.051   1.00 76.46  ? 376 VAL C CA  1 
ATOM 8358  C C   . VAL C 1 376 ? -43.440 -60.325 0.229   1.00 81.63  ? 376 VAL C C   1 
ATOM 8359  O O   . VAL C 1 376 ? -43.473 -59.388 -0.584  1.00 85.55  ? 376 VAL C O   1 
ATOM 8360  C CB  . VAL C 1 376 ? -41.135 -61.237 0.743   1.00 75.72  ? 376 VAL C CB  1 
ATOM 8361  C CG1 . VAL C 1 376 ? -40.154 -62.351 0.427   1.00 71.36  ? 376 VAL C CG1 1 
ATOM 8362  C CG2 . VAL C 1 376 ? -40.562 -59.890 0.339   1.00 77.35  ? 376 VAL C CG2 1 
ATOM 8363  N N   . VAL C 1 377 ? -44.241 -60.381 1.288   1.00 86.45  ? 377 VAL C N   1 
ATOM 8364  C CA  . VAL C 1 377 ? -45.241 -59.355 1.556   1.00 93.14  ? 377 VAL C CA  1 
ATOM 8365  C C   . VAL C 1 377 ? -44.588 -58.245 2.367   1.00 100.34 ? 377 VAL C C   1 
ATOM 8366  O O   . VAL C 1 377 ? -44.116 -58.476 3.486   1.00 112.39 ? 377 VAL C O   1 
ATOM 8367  C CB  . VAL C 1 377 ? -46.455 -59.940 2.291   1.00 96.00  ? 377 VAL C CB  1 
ATOM 8368  C CG1 . VAL C 1 377 ? -47.589 -58.925 2.333   1.00 90.87  ? 377 VAL C CG1 1 
ATOM 8369  C CG2 . VAL C 1 377 ? -46.909 -61.230 1.625   1.00 84.24  ? 377 VAL C CG2 1 
ATOM 8370  N N   . ARG C 1 378 ? -44.523 -57.043 1.783   1.00 105.28 ? 378 ARG C N   1 
ATOM 8371  C CA  . ARG C 1 378 ? -43.859 -55.895 2.459   1.00 102.02 ? 378 ARG C CA  1 
ATOM 8372  C C   . ARG C 1 378 ? -44.725 -55.412 3.626   1.00 110.15 ? 378 ARG C C   1 
ATOM 8373  O O   . ARG C 1 378 ? -45.906 -55.093 3.389   1.00 109.11 ? 378 ARG C O   1 
ATOM 8374  C CB  . ARG C 1 378 ? -43.615 -54.761 1.458   1.00 112.54 ? 378 ARG C CB  1 
ATOM 8375  C CG  . ARG C 1 378 ? -42.604 -53.725 1.925   1.00 116.16 ? 378 ARG C CG  1 
ATOM 8376  C CD  . ARG C 1 378 ? -42.033 -52.917 0.775   1.00 110.73 ? 378 ARG C CD  1 
ATOM 8377  N NE  . ARG C 1 378 ? -40.578 -52.959 0.735   1.00 113.02 ? 378 ARG C NE  1 
ATOM 8378  C CZ  . ARG C 1 378 ? -39.860 -52.976 -0.382  1.00 107.97 ? 378 ARG C CZ  1 
ATOM 8379  N NH1 . ARG C 1 378 ? -40.462 -52.954 -1.558  1.00 97.75  ? 378 ARG C NH1 1 
ATOM 8380  N NH2 . ARG C 1 378 ? -38.541 -53.019 -0.319  1.00 106.83 ? 378 ARG C NH2 1 
ATOM 8381  N N   . ASP C 1 379 ? -44.151 -55.355 4.831   1.00 121.52 ? 379 ASP C N   1 
ATOM 8382  C CA  . ASP C 1 379 ? -44.900 -54.852 6.015   1.00 129.71 ? 379 ASP C CA  1 
ATOM 8383  C C   . ASP C 1 379 ? -44.695 -53.336 6.125   1.00 131.73 ? 379 ASP C C   1 
ATOM 8384  O O   . ASP C 1 379 ? -45.601 -52.657 6.644   1.00 128.12 ? 379 ASP C O   1 
ATOM 8385  C CB  . ASP C 1 379 ? -44.475 -55.580 7.292   1.00 129.11 ? 379 ASP C CB  1 
ATOM 8386  C CG  . ASP C 1 379 ? -44.949 -57.022 7.345   1.00 135.19 ? 379 ASP C CG  1 
ATOM 8387  O OD1 . ASP C 1 379 ? -45.837 -57.375 6.543   1.00 134.81 ? 379 ASP C OD1 1 
ATOM 8388  O OD2 . ASP C 1 379 ? -44.423 -57.777 8.186   1.00 134.27 ? 379 ASP C OD2 1 
ATOM 8389  N N   . GLU C 1 380 ? -43.549 -52.836 5.649   1.00 127.22 ? 380 GLU C N   1 
ATOM 8390  C CA  . GLU C 1 380 ? -43.269 -51.376 5.691   1.00 128.72 ? 380 GLU C CA  1 
ATOM 8391  C C   . GLU C 1 380 ? -43.327 -50.816 4.266   1.00 128.76 ? 380 GLU C C   1 
ATOM 8392  O O   . GLU C 1 380 ? -44.277 -51.160 3.538   1.00 129.65 ? 380 GLU C O   1 
ATOM 8393  C CB  . GLU C 1 380 ? -41.905 -51.119 6.332   1.00 134.24 ? 380 GLU C CB  1 
ATOM 8394  C CG  . GLU C 1 380 ? -41.849 -51.479 7.806   1.00 136.31 ? 380 GLU C CG  1 
ATOM 8395  C CD  . GLU C 1 380 ? -40.479 -51.295 8.437   1.00 141.38 ? 380 GLU C CD  1 
ATOM 8396  O OE1 . GLU C 1 380 ? -39.512 -51.066 7.685   1.00 129.16 ? 380 GLU C OE1 1 
ATOM 8397  O OE2 . GLU C 1 380 ? -40.386 -51.371 9.678   1.00 151.10 ? 380 GLU C OE2 1 
ATOM 8398  N N   . ASN C 1 381 ? -42.351 -49.983 3.893   1.00 131.71 ? 381 ASN C N   1 
ATOM 8399  C CA  . ASN C 1 381 ? -42.291 -49.416 2.519   1.00 139.69 ? 381 ASN C CA  1 
ATOM 8400  C C   . ASN C 1 381 ? -40.839 -49.480 2.042   1.00 142.37 ? 381 ASN C C   1 
ATOM 8401  O O   . ASN C 1 381 ? -40.621 -49.589 0.820   1.00 143.24 ? 381 ASN C O   1 
ATOM 8402  C CB  . ASN C 1 381 ? -42.860 -47.996 2.451   1.00 145.13 ? 381 ASN C CB  1 
ATOM 8403  C CG  . ASN C 1 381 ? -42.533 -47.154 3.666   1.00 142.50 ? 381 ASN C CG  1 
ATOM 8404  O OD1 . ASN C 1 381 ? -41.406 -46.691 3.825   1.00 137.43 ? 381 ASN C OD1 1 
ATOM 8405  N ND2 . ASN C 1 381 ? -43.516 -46.937 4.526   1.00 138.20 ? 381 ASN C ND2 1 
ATOM 8406  N N   . GLY C 1 382 ? -39.889 -49.422 2.979   1.00 136.72 ? 382 GLY C N   1 
ATOM 8407  C CA  . GLY C 1 382 ? -38.460 -49.510 2.621   1.00 122.03 ? 382 GLY C CA  1 
ATOM 8408  C C   . GLY C 1 382 ? -38.011 -50.955 2.512   1.00 121.70 ? 382 GLY C C   1 
ATOM 8409  O O   . GLY C 1 382 ? -37.227 -51.259 1.590   1.00 122.77 ? 382 GLY C O   1 
ATOM 8410  N N   . LYS C 1 383 ? -38.481 -51.801 3.425   1.00 119.01 ? 383 LYS C N   1 
ATOM 8411  C CA  . LYS C 1 383 ? -37.950 -53.181 3.404   1.00 115.91 ? 383 LYS C CA  1 
ATOM 8412  C C   . LYS C 1 383 ? -38.959 -54.177 3.957   1.00 110.06 ? 383 LYS C C   1 
ATOM 8413  O O   . LYS C 1 383 ? -40.102 -53.791 4.249   1.00 109.70 ? 383 LYS C O   1 
ATOM 8414  C CB  . LYS C 1 383 ? -36.634 -53.263 4.183   1.00 115.37 ? 383 LYS C CB  1 
ATOM 8415  C CG  . LYS C 1 383 ? -36.686 -52.781 5.627   1.00 118.57 ? 383 LYS C CG  1 
ATOM 8416  C CD  . LYS C 1 383 ? -35.512 -53.264 6.451   1.00 115.69 ? 383 LYS C CD  1 
ATOM 8417  C CE  . LYS C 1 383 ? -34.974 -52.218 7.406   1.00 116.11 ? 383 LYS C CE  1 
ATOM 8418  N NZ  . LYS C 1 383 ? -34.361 -51.070 6.695   1.00 107.93 ? 383 LYS C NZ  1 
ATOM 8419  N N   . TYR C 1 384 ? -38.505 -55.414 4.102   1.00 104.46 ? 384 TYR C N   1 
ATOM 8420  C CA  . TYR C 1 384 ? -39.395 -56.484 4.586   1.00 103.24 ? 384 TYR C CA  1 
ATOM 8421  C C   . TYR C 1 384 ? -38.908 -56.938 5.957   1.00 103.60 ? 384 TYR C C   1 
ATOM 8422  O O   . TYR C 1 384 ? -37.826 -56.499 6.389   1.00 94.58  ? 384 TYR C O   1 
ATOM 8423  C CB  . TYR C 1 384 ? -39.309 -57.643 3.601   1.00 99.46  ? 384 TYR C CB  1 
ATOM 8424  C CG  . TYR C 1 384 ? -39.275 -57.230 2.155   1.00 92.67  ? 384 TYR C CG  1 
ATOM 8425  C CD1 . TYR C 1 384 ? -40.402 -56.708 1.553   1.00 100.05 ? 384 TYR C CD1 1 
ATOM 8426  C CD2 . TYR C 1 384 ? -38.134 -57.378 1.385   1.00 79.89  ? 384 TYR C CD2 1 
ATOM 8427  C CE1 . TYR C 1 384 ? -40.403 -56.348 0.219   1.00 100.60 ? 384 TYR C CE1 1 
ATOM 8428  C CE2 . TYR C 1 384 ? -38.113 -57.014 0.050   1.00 71.91  ? 384 TYR C CE2 1 
ATOM 8429  C CZ  . TYR C 1 384 ? -39.255 -56.499 -0.532  1.00 86.95  ? 384 TYR C CZ  1 
ATOM 8430  O OH  . TYR C 1 384 ? -39.282 -56.135 -1.841  1.00 86.93  ? 384 TYR C OH  1 
ATOM 8431  N N   . LYS C 1 385 ? -39.681 -57.812 6.602   1.00 103.52 ? 385 LYS C N   1 
ATOM 8432  C CA  . LYS C 1 385 ? -39.338 -58.257 7.971   1.00 94.32  ? 385 LYS C CA  1 
ATOM 8433  C C   . LYS C 1 385 ? -39.067 -59.760 7.951   1.00 90.62  ? 385 LYS C C   1 
ATOM 8434  O O   . LYS C 1 385 ? -39.510 -60.409 6.998   1.00 93.01  ? 385 LYS C O   1 
ATOM 8435  C CB  . LYS C 1 385 ? -40.479 -57.867 8.910   1.00 98.93  ? 385 LYS C CB  1 
ATOM 8436  C CG  . LYS C 1 385 ? -40.782 -56.377 8.974   1.00 102.38 ? 385 LYS C CG  1 
ATOM 8437  C CD  . LYS C 1 385 ? -41.703 -56.015 10.115  1.00 115.96 ? 385 LYS C CD  1 
ATOM 8438  C CE  . LYS C 1 385 ? -42.091 -54.553 10.126  1.00 121.48 ? 385 LYS C CE  1 
ATOM 8439  N NZ  . LYS C 1 385 ? -43.429 -54.350 10.729  1.00 128.83 ? 385 LYS C NZ  1 
ATOM 8440  N N   . ARG C 1 386 ? -38.380 -60.283 8.966   1.00 89.12  ? 386 ARG C N   1 
ATOM 8441  C CA  . ARG C 1 386 ? -37.979 -61.709 8.965   1.00 85.57  ? 386 ARG C CA  1 
ATOM 8442  C C   . ARG C 1 386 ? -39.185 -62.626 8.801   1.00 82.10  ? 386 ARG C C   1 
ATOM 8443  O O   . ARG C 1 386 ? -39.068 -63.596 8.051   1.00 79.69  ? 386 ARG C O   1 
ATOM 8444  C CB  . ARG C 1 386 ? -37.315 -62.014 10.307  1.00 93.54  ? 386 ARG C CB  1 
ATOM 8445  C CG  . ARG C 1 386 ? -36.256 -60.999 10.707  1.00 92.19  ? 386 ARG C CG  1 
ATOM 8446  C CD  . ARG C 1 386 ? -36.356 -60.482 12.129  1.00 85.68  ? 386 ARG C CD  1 
ATOM 8447  N NE  . ARG C 1 386 ? -35.115 -59.811 12.484  1.00 88.28  ? 386 ARG C NE  1 
ATOM 8448  C CZ  . ARG C 1 386 ? -35.022 -58.766 13.297  1.00 95.61  ? 386 ARG C CZ  1 
ATOM 8449  N NH1 . ARG C 1 386 ? -36.107 -58.262 13.857  1.00 91.43  ? 386 ARG C NH1 1 
ATOM 8450  N NH2 . ARG C 1 386 ? -33.840 -58.231 13.548  1.00 105.48 ? 386 ARG C NH2 1 
ATOM 8451  N N   . GLU C 1 387 ? -40.274 -62.364 9.516   1.00 82.31  ? 387 GLU C N   1 
ATOM 8452  C CA  . GLU C 1 387 ? -41.499 -63.183 9.313   1.00 90.54  ? 387 GLU C CA  1 
ATOM 8453  C C   . GLU C 1 387 ? -41.845 -63.248 7.822   1.00 85.96  ? 387 GLU C C   1 
ATOM 8454  O O   . GLU C 1 387 ? -41.937 -64.370 7.305   1.00 83.04  ? 387 GLU C O   1 
ATOM 8455  C CB  . GLU C 1 387 ? -42.669 -62.617 10.117  1.00 95.24  ? 387 GLU C CB  1 
ATOM 8456  C CG  . GLU C 1 387 ? -42.888 -63.329 11.440  1.00 91.28  ? 387 GLU C CG  1 
ATOM 8457  C CD  . GLU C 1 387 ? -42.904 -64.846 11.358  1.00 100.89 ? 387 GLU C CD  1 
ATOM 8458  O OE1 . GLU C 1 387 ? -43.834 -65.394 10.736  1.00 102.25 ? 387 GLU C OE1 1 
ATOM 8459  O OE2 . GLU C 1 387 ? -41.992 -65.477 11.927  1.00 98.68  ? 387 GLU C OE2 1 
ATOM 8460  N N   . GLY C 1 388 ? -42.046 -62.096 7.170   1.00 81.44  ? 388 GLY C N   1 
ATOM 8461  C CA  . GLY C 1 388 ? -42.397 -62.078 5.760   1.00 86.23  ? 388 GLY C CA  1 
ATOM 8462  C C   . GLY C 1 388 ? -41.491 -62.941 4.904   1.00 77.84  ? 388 GLY C C   1 
ATOM 8463  O O   . GLY C 1 388 ? -41.933 -63.513 3.903   1.00 73.45  ? 388 GLY C O   1 
ATOM 8464  N N   . ILE C 1 389 ? -40.218 -63.059 5.284   1.00 73.98  ? 389 ILE C N   1 
ATOM 8465  C CA  . ILE C 1 389 ? -39.274 -63.862 4.515   1.00 72.81  ? 389 ILE C CA  1 
ATOM 8466  C C   . ILE C 1 389 ? -39.398 -65.337 4.877   1.00 80.83  ? 389 ILE C C   1 
ATOM 8467  O O   . ILE C 1 389 ? -39.482 -66.204 3.998   1.00 81.75  ? 389 ILE C O   1 
ATOM 8468  C CB  . ILE C 1 389 ? -37.841 -63.345 4.739   1.00 71.88  ? 389 ILE C CB  1 
ATOM 8469  C CG1 . ILE C 1 389 ? -37.709 -61.907 4.234   1.00 76.56  ? 389 ILE C CG1 1 
ATOM 8470  C CG2 . ILE C 1 389 ? -36.830 -64.260 4.065   1.00 72.71  ? 389 ILE C CG2 1 
ATOM 8471  C CD1 . ILE C 1 389 ? -36.319 -61.335 4.378   1.00 70.43  ? 389 ILE C CD1 1 
ATOM 8472  N N   . ALA C 1 390 ? -39.394 -65.634 6.177   1.00 78.41  ? 390 ALA C N   1 
ATOM 8473  C CA  . ALA C 1 390 ? -39.465 -67.020 6.626   1.00 75.04  ? 390 ALA C CA  1 
ATOM 8474  C C   . ALA C 1 390 ? -40.766 -67.679 6.183   1.00 76.77  ? 390 ALA C C   1 
ATOM 8475  O O   . ALA C 1 390 ? -40.770 -68.849 5.783   1.00 78.51  ? 390 ALA C O   1 
ATOM 8476  C CB  . ALA C 1 390 ? -39.321 -67.087 8.145   1.00 85.98  ? 390 ALA C CB  1 
ATOM 8477  N N   . GLU C 1 391 ? -41.878 -66.945 6.252   1.00 75.89  ? 391 GLU C N   1 
ATOM 8478  C CA  . GLU C 1 391 ? -43.160 -67.502 5.836   1.00 79.91  ? 391 GLU C CA  1 
ATOM 8479  C C   . GLU C 1 391 ? -43.109 -67.965 4.388   1.00 77.55  ? 391 GLU C C   1 
ATOM 8480  O O   . GLU C 1 391 ? -43.460 -69.109 4.083   1.00 72.82  ? 391 GLU C O   1 
ATOM 8481  C CB  . GLU C 1 391 ? -44.275 -66.474 6.033   1.00 80.71  ? 391 GLU C CB  1 
ATOM 8482  C CG  . GLU C 1 391 ? -44.802 -66.389 7.458   1.00 91.39  ? 391 GLU C CG  1 
ATOM 8483  C CD  . GLU C 1 391 ? -45.959 -65.417 7.592   1.00 101.57 ? 391 GLU C CD  1 
ATOM 8484  O OE1 . GLU C 1 391 ? -46.507 -65.000 6.552   1.00 103.53 ? 391 GLU C OE1 1 
ATOM 8485  O OE2 . GLU C 1 391 ? -46.315 -65.071 8.738   1.00 106.25 ? 391 GLU C OE2 1 
ATOM 8486  N N   . VAL C 1 392 ? -42.654 -67.096 3.482   1.00 77.66  ? 392 VAL C N   1 
ATOM 8487  C CA  . VAL C 1 392 ? -42.663 -67.456 2.071   1.00 78.00  ? 392 VAL C CA  1 
ATOM 8488  C C   . VAL C 1 392 ? -41.637 -68.546 1.781   1.00 75.31  ? 392 VAL C C   1 
ATOM 8489  O O   . VAL C 1 392 ? -41.885 -69.424 0.944   1.00 67.74  ? 392 VAL C O   1 
ATOM 8490  C CB  . VAL C 1 392 ? -42.451 -66.213 1.186   1.00 74.88  ? 392 VAL C CB  1 
ATOM 8491  C CG1 . VAL C 1 392 ? -43.491 -65.149 1.517   1.00 74.44  ? 392 VAL C CG1 1 
ATOM 8492  C CG2 . VAL C 1 392 ? -41.055 -65.654 1.358   1.00 84.68  ? 392 VAL C CG2 1 
ATOM 8493  N N   . ILE C 1 393 ? -40.494 -68.537 2.476   1.00 75.71  ? 393 ILE C N   1 
ATOM 8494  C CA  . ILE C 1 393 ? -39.511 -69.602 2.269   1.00 72.81  ? 393 ILE C CA  1 
ATOM 8495  C C   . ILE C 1 393 ? -40.110 -70.951 2.649   1.00 67.76  ? 393 ILE C C   1 
ATOM 8496  O O   . ILE C 1 393 ? -40.036 -71.923 1.885   1.00 67.05  ? 393 ILE C O   1 
ATOM 8497  C CB  . ILE C 1 393 ? -38.220 -69.314 3.056   1.00 65.84  ? 393 ILE C CB  1 
ATOM 8498  C CG1 . ILE C 1 393 ? -37.485 -68.123 2.445   1.00 68.11  ? 393 ILE C CG1 1 
ATOM 8499  C CG2 . ILE C 1 393 ? -37.321 -70.544 3.067   1.00 72.06  ? 393 ILE C CG2 1 
ATOM 8500  C CD1 . ILE C 1 393 ? -36.213 -67.760 3.175   1.00 73.30  ? 393 ILE C CD1 1 
ATOM 8501  N N   . ARG C 1 394 ? -40.731 -71.027 3.830   1.00 70.25  ? 394 ARG C N   1 
ATOM 8502  C CA  . ARG C 1 394 ? -41.341 -72.280 4.264   1.00 80.07  ? 394 ARG C CA  1 
ATOM 8503  C C   . ARG C 1 394 ? -42.475 -72.690 3.334   1.00 76.04  ? 394 ARG C C   1 
ATOM 8504  O O   . ARG C 1 394 ? -42.605 -73.870 2.991   1.00 77.34  ? 394 ARG C O   1 
ATOM 8505  C CB  . ARG C 1 394 ? -41.847 -72.156 5.702   1.00 78.84  ? 394 ARG C CB  1 
ATOM 8506  C CG  . ARG C 1 394 ? -40.773 -71.815 6.720   1.00 77.68  ? 394 ARG C CG  1 
ATOM 8507  C CD  . ARG C 1 394 ? -41.359 -71.689 8.120   1.00 83.82  ? 394 ARG C CD  1 
ATOM 8508  N NE  . ARG C 1 394 ? -41.450 -72.976 8.797   1.00 93.77  ? 394 ARG C NE  1 
ATOM 8509  C CZ  . ARG C 1 394 ? -40.542 -73.439 9.648   1.00 99.48  ? 394 ARG C CZ  1 
ATOM 8510  N NH1 . ARG C 1 394 ? -39.463 -72.739 9.954   1.00 100.69 ? 394 ARG C NH1 1 
ATOM 8511  N NH2 . ARG C 1 394 ? -40.724 -74.633 10.204  1.00 96.89  ? 394 ARG C NH2 1 
ATOM 8512  N N   . LYS C 1 395 ? -43.301 -71.728 2.913   1.00 70.44  ? 395 LYS C N   1 
ATOM 8513  C CA  . LYS C 1 395 ? -44.422 -72.040 2.030   1.00 72.42  ? 395 LYS C CA  1 
ATOM 8514  C C   . LYS C 1 395 ? -43.934 -72.637 0.717   1.00 72.66  ? 395 LYS C C   1 
ATOM 8515  O O   . LYS C 1 395 ? -44.464 -73.652 0.251   1.00 74.67  ? 395 LYS C O   1 
ATOM 8516  C CB  . LYS C 1 395 ? -45.253 -70.781 1.772   1.00 80.57  ? 395 LYS C CB  1 
ATOM 8517  C CG  . LYS C 1 395 ? -46.054 -70.295 2.973   1.00 88.07  ? 395 LYS C CG  1 
ATOM 8518  C CD  . LYS C 1 395 ? -46.435 -68.826 2.825   1.00 86.39  ? 395 LYS C CD  1 
ATOM 8519  C CE  . LYS C 1 395 ? -47.708 -68.649 2.015   1.00 81.36  ? 395 LYS C CE  1 
ATOM 8520  N NZ  . LYS C 1 395 ? -48.909 -69.089 2.782   1.00 82.02  ? 395 LYS C NZ  1 
ATOM 8521  N N   . VAL C 1 396 ? -42.912 -72.033 0.116   1.00 67.53  ? 396 VAL C N   1 
ATOM 8522  C CA  . VAL C 1 396 ? -42.464 -72.466 -1.204  1.00 66.36  ? 396 VAL C CA  1 
ATOM 8523  C C   . VAL C 1 396 ? -41.686 -73.773 -1.111  1.00 65.66  ? 396 VAL C C   1 
ATOM 8524  O O   . VAL C 1 396 ? -42.036 -74.769 -1.756  1.00 69.70  ? 396 VAL C O   1 
ATOM 8525  C CB  . VAL C 1 396 ? -41.627 -71.363 -1.881  1.00 62.74  ? 396 VAL C CB  1 
ATOM 8526  C CG1 . VAL C 1 396 ? -40.959 -71.902 -3.137  1.00 50.05  ? 396 VAL C CG1 1 
ATOM 8527  C CG2 . VAL C 1 396 ? -42.504 -70.169 -2.209  1.00 59.23  ? 396 VAL C CG2 1 
ATOM 8528  N N   . VAL C 1 397 ? -40.623 -73.798 -0.308  1.00 68.35  ? 397 VAL C N   1 
ATOM 8529  C CA  . VAL C 1 397 ? -39.644 -74.875 -0.450  1.00 69.68  ? 397 VAL C CA  1 
ATOM 8530  C C   . VAL C 1 397 ? -40.066 -76.134 0.302   1.00 68.15  ? 397 VAL C C   1 
ATOM 8531  O O   . VAL C 1 397 ? -39.848 -77.252 -0.176  1.00 70.50  ? 397 VAL C O   1 
ATOM 8532  C CB  . VAL C 1 397 ? -38.252 -74.391 -0.006  1.00 59.51  ? 397 VAL C CB  1 
ATOM 8533  C CG1 . VAL C 1 397 ? -37.200 -75.450 -0.318  1.00 65.34  ? 397 VAL C CG1 1 
ATOM 8534  C CG2 . VAL C 1 397 ? -37.906 -73.076 -0.695  1.00 61.13  ? 397 VAL C CG2 1 
ATOM 8535  N N   . VAL C 1 398 ? -40.677 -75.993 1.478   1.00 66.49  ? 398 VAL C N   1 
ATOM 8536  C CA  . VAL C 1 398 ? -40.863 -77.125 2.384   1.00 76.58  ? 398 VAL C CA  1 
ATOM 8537  C C   . VAL C 1 398 ? -42.323 -77.418 2.707   1.00 78.74  ? 398 VAL C C   1 
ATOM 8538  O O   . VAL C 1 398 ? -42.607 -78.476 3.288   1.00 86.15  ? 398 VAL C O   1 
ATOM 8539  C CB  . VAL C 1 398 ? -40.065 -76.919 3.691   1.00 69.28  ? 398 VAL C CB  1 
ATOM 8540  C CG1 . VAL C 1 398 ? -40.842 -76.057 4.672   1.00 69.57  ? 398 VAL C CG1 1 
ATOM 8541  C CG2 . VAL C 1 398 ? -39.677 -78.253 4.311   1.00 71.62  ? 398 VAL C CG2 1 
ATOM 8542  N N   . GLU C 1 399 ? -43.261 -76.541 2.361   1.00 68.57  ? 399 GLU C N   1 
ATOM 8543  C CA  . GLU C 1 399 ? -44.656 -76.733 2.728   1.00 71.96  ? 399 GLU C CA  1 
ATOM 8544  C C   . GLU C 1 399 ? -45.468 -77.229 1.538   1.00 78.86  ? 399 GLU C C   1 
ATOM 8545  O O   . GLU C 1 399 ? -45.080 -77.073 0.378   1.00 79.55  ? 399 GLU C O   1 
ATOM 8546  C CB  . GLU C 1 399 ? -45.258 -75.430 3.269   1.00 73.26  ? 399 GLU C CB  1 
ATOM 8547  C CG  . GLU C 1 399 ? -46.121 -75.607 4.517   1.00 71.69  ? 399 GLU C CG  1 
ATOM 8548  C CD  . GLU C 1 399 ? -47.514 -76.119 4.205   1.00 82.44  ? 399 GLU C CD  1 
ATOM 8549  O OE1 . GLU C 1 399 ? -47.975 -75.921 3.062   1.00 78.35  ? 399 GLU C OE1 1 
ATOM 8550  O OE2 . GLU C 1 399 ? -48.147 -76.719 5.102   1.00 91.21  ? 399 GLU C OE2 1 
ATOM 8551  N N   . LYS C 1 400 ? -46.617 -77.835 1.847   1.00 76.79  ? 400 LYS C N   1 
ATOM 8552  C CA  . LYS C 1 400 ? -47.497 -78.340 0.797   1.00 75.91  ? 400 LYS C CA  1 
ATOM 8553  C C   . LYS C 1 400 ? -48.156 -77.212 0.013   1.00 77.94  ? 400 LYS C C   1 
ATOM 8554  O O   . LYS C 1 400 ? -48.440 -77.375 -1.177  1.00 80.80  ? 400 LYS C O   1 
ATOM 8555  C CB  . LYS C 1 400 ? -48.573 -79.248 1.393   1.00 77.26  ? 400 LYS C CB  1 
ATOM 8556  C CG  . LYS C 1 400 ? -48.046 -80.526 2.015   1.00 82.65  ? 400 LYS C CG  1 
ATOM 8557  C CD  . LYS C 1 400 ? -49.186 -81.397 2.531   1.00 85.24  ? 400 LYS C CD  1 
ATOM 8558  C CE  . LYS C 1 400 ? -48.674 -82.717 3.084   1.00 85.63  ? 400 LYS C CE  1 
ATOM 8559  N NZ  . LYS C 1 400 ? -49.784 -83.563 3.609   1.00 82.78  ? 400 LYS C NZ  1 
ATOM 8560  N N   . SER C 1 401 ? -48.414 -76.070 0.661   1.00 73.04  ? 401 SER C N   1 
ATOM 8561  C CA  . SER C 1 401 ? -49.078 -74.959 -0.015  1.00 74.50  ? 401 SER C CA  1 
ATOM 8562  C C   . SER C 1 401 ? -48.280 -74.446 -1.206  1.00 69.55  ? 401 SER C C   1 
ATOM 8563  O O   . SER C 1 401 ? -48.865 -73.856 -2.124  1.00 71.74  ? 401 SER C O   1 
ATOM 8564  C CB  . SER C 1 401 ? -49.329 -73.817 0.972   1.00 62.15  ? 401 SER C CB  1 
ATOM 8565  O OG  . SER C 1 401 ? -48.109 -73.291 1.461   1.00 79.91  ? 401 SER C OG  1 
ATOM 8566  N N   . GLY C 1 402 ? -46.969 -74.659 -1.218  1.00 70.43  ? 402 GLY C N   1 
ATOM 8567  C CA  . GLY C 1 402 ? -46.126 -74.277 -2.328  1.00 72.57  ? 402 GLY C CA  1 
ATOM 8568  C C   . GLY C 1 402 ? -45.937 -75.344 -3.380  1.00 69.80  ? 402 GLY C C   1 
ATOM 8569  O O   . GLY C 1 402 ? -45.159 -75.135 -4.318  1.00 68.70  ? 402 GLY C O   1 
ATOM 8570  N N   . GLU C 1 403 ? -46.624 -76.488 -3.256  1.00 63.83  ? 403 GLU C N   1 
ATOM 8571  C CA  . GLU C 1 403 ? -46.504 -77.533 -4.269  1.00 74.01  ? 403 GLU C CA  1 
ATOM 8572  C C   . GLU C 1 403 ? -46.918 -77.014 -5.642  1.00 70.46  ? 403 GLU C C   1 
ATOM 8573  O O   . GLU C 1 403 ? -46.260 -77.304 -6.648  1.00 76.01  ? 403 GLU C O   1 
ATOM 8574  C CB  . GLU C 1 403 ? -47.336 -78.748 -3.868  1.00 72.61  ? 403 GLU C CB  1 
ATOM 8575  C CG  . GLU C 1 403 ? -46.775 -80.070 -4.371  1.00 74.48  ? 403 GLU C CG  1 
ATOM 8576  C CD  . GLU C 1 403 ? -47.574 -80.653 -5.520  1.00 77.87  ? 403 GLU C CD  1 
ATOM 8577  O OE1 . GLU C 1 403 ? -48.795 -80.392 -5.588  1.00 78.07  ? 403 GLU C OE1 1 
ATOM 8578  O OE2 . GLU C 1 403 ? -46.984 -81.372 -6.354  1.00 79.45  ? 403 GLU C OE2 1 
ATOM 8579  N N   . VAL C 1 404 ? -47.969 -76.209 -5.681  1.00 66.33  ? 404 VAL C N   1 
ATOM 8580  C CA  . VAL C 1 404 ? -48.342 -75.612 -6.989  1.00 70.00  ? 404 VAL C CA  1 
ATOM 8581  C C   . VAL C 1 404 ? -47.083 -74.979 -7.584  1.00 70.14  ? 404 VAL C C   1 
ATOM 8582  O O   . VAL C 1 404 ? -46.694 -75.385 -8.704  1.00 70.00  ? 404 VAL C O   1 
ATOM 8583  C CB  . VAL C 1 404 ? -49.485 -74.593 -6.841  1.00 71.29  ? 404 VAL C CB  1 
ATOM 8584  C CG1 . VAL C 1 404 ? -49.822 -73.929 -8.166  1.00 76.85  ? 404 VAL C CG1 1 
ATOM 8585  C CG2 . VAL C 1 404 ? -50.723 -75.234 -6.233  1.00 74.65  ? 404 VAL C CG2 1 
ATOM 8586  N N   . ILE C 1 405 ? -46.395 -74.130 -6.821  1.00 64.99  ? 405 ILE C N   1 
ATOM 8587  C CA  . ILE C 1 405 ? -45.239 -73.380 -7.389  1.00 57.41  ? 405 ILE C CA  1 
ATOM 8588  C C   . ILE C 1 405 ? -44.152 -74.347 -7.872  1.00 55.19  ? 405 ILE C C   1 
ATOM 8589  O O   . ILE C 1 405 ? -43.657 -74.187 -9.015  1.00 54.53  ? 405 ILE C O   1 
ATOM 8590  C CB  . ILE C 1 405 ? -44.743 -72.401 -6.311  1.00 48.36  ? 405 ILE C CB  1 
ATOM 8591  C CG1 . ILE C 1 405 ? -45.851 -71.435 -5.888  1.00 54.27  ? 405 ILE C CG1 1 
ATOM 8592  C CG2 . ILE C 1 405 ? -43.491 -71.665 -6.749  1.00 49.52  ? 405 ILE C CG2 1 
ATOM 8593  C CD1 . ILE C 1 405 ? -45.495 -70.577 -4.704  1.00 55.95  ? 405 ILE C CD1 1 
ATOM 8594  N N   . ARG C 1 406 ? -43.839 -75.353 -7.066  1.00 55.09  ? 406 ARG C N   1 
ATOM 8595  C CA  . ARG C 1 406 ? -42.737 -76.278 -7.417  1.00 56.66  ? 406 ARG C CA  1 
ATOM 8596  C C   . ARG C 1 406 ? -43.089 -77.074 -8.668  1.00 55.69  ? 406 ARG C C   1 
ATOM 8597  O O   . ARG C 1 406 ? -42.213 -77.221 -9.591  1.00 62.96  ? 406 ARG C O   1 
ATOM 8598  C CB  . ARG C 1 406 ? -42.468 -77.176 -6.212  1.00 61.12  ? 406 ARG C CB  1 
ATOM 8599  C CG  . ARG C 1 406 ? -42.058 -76.423 -4.954  1.00 66.76  ? 406 ARG C CG  1 
ATOM 8600  C CD  . ARG C 1 406 ? -41.547 -77.355 -3.873  1.00 64.34  ? 406 ARG C CD  1 
ATOM 8601  N NE  . ARG C 1 406 ? -42.560 -78.302 -3.435  1.00 66.12  ? 406 ARG C NE  1 
ATOM 8602  C CZ  . ARG C 1 406 ? -43.231 -78.215 -2.295  1.00 69.73  ? 406 ARG C CZ  1 
ATOM 8603  N NH1 . ARG C 1 406 ? -42.985 -77.230 -1.455  1.00 67.44  ? 406 ARG C NH1 1 
ATOM 8604  N NH2 . ARG C 1 406 ? -44.137 -79.126 -1.990  1.00 70.82  ? 406 ARG C NH2 1 
ATOM 8605  N N   . ARG C 1 407 ? -44.317 -77.599 -8.722  1.00 59.91  ? 407 ARG C N   1 
ATOM 8606  C CA  . ARG C 1 407 ? -44.761 -78.406 -9.890  1.00 65.69  ? 407 ARG C CA  1 
ATOM 8607  C C   . ARG C 1 407 ? -44.606 -77.573 -11.164 1.00 61.65  ? 407 ARG C C   1 
ATOM 8608  O O   . ARG C 1 407 ? -44.048 -78.097 -12.146 1.00 66.52  ? 407 ARG C O   1 
ATOM 8609  C CB  . ARG C 1 407 ? -46.212 -78.851 -9.695  1.00 62.92  ? 407 ARG C CB  1 
ATOM 8610  C CG  . ARG C 1 407 ? -46.806 -79.599 -10.879 1.00 73.37  ? 407 ARG C CG  1 
ATOM 8611  C CD  . ARG C 1 407 ? -48.265 -79.970 -10.688 1.00 77.80  ? 407 ARG C CD  1 
ATOM 8612  N NE  . ARG C 1 407 ? -49.157 -78.822 -10.596 1.00 80.96  ? 407 ARG C NE  1 
ATOM 8613  C CZ  . ARG C 1 407 ? -49.671 -78.347 -9.466  1.00 80.13  ? 407 ARG C CZ  1 
ATOM 8614  N NH1 . ARG C 1 407 ? -49.387 -78.926 -8.311  1.00 80.73  ? 407 ARG C NH1 1 
ATOM 8615  N NH2 . ARG C 1 407 ? -50.472 -77.298 -9.495  1.00 86.23  ? 407 ARG C NH2 1 
ATOM 8616  N N   . LYS C 1 408 ? -45.051 -76.319 -11.115 1.00 52.69  ? 408 LYS C N   1 
ATOM 8617  C CA  . LYS C 1 408 ? -45.015 -75.447 -12.311 1.00 55.05  ? 408 LYS C CA  1 
ATOM 8618  C C   . LYS C 1 408 ? -43.573 -75.200 -12.740 1.00 58.67  ? 408 LYS C C   1 
ATOM 8619  O O   . LYS C 1 408 ? -43.317 -75.218 -13.946 1.00 64.43  ? 408 LYS C O   1 
ATOM 8620  C CB  . LYS C 1 408 ? -45.702 -74.118 -12.004 1.00 58.01  ? 408 LYS C CB  1 
ATOM 8621  C CG  . LYS C 1 408 ? -47.172 -74.203 -11.618 1.00 67.82  ? 408 LYS C CG  1 
ATOM 8622  C CD  . LYS C 1 408 ? -48.079 -74.737 -12.709 1.00 76.39  ? 408 LYS C CD  1 
ATOM 8623  C CE  . LYS C 1 408 ? -49.540 -74.744 -12.308 1.00 80.40  ? 408 LYS C CE  1 
ATOM 8624  N NZ  . LYS C 1 408 ? -50.418 -75.237 -13.395 1.00 78.74  ? 408 LYS C NZ  1 
ATOM 8625  N N   . ALA C 1 409 ? -42.680 -74.969 -11.787 1.00 52.21  ? 409 ALA C N   1 
ATOM 8626  C CA  . ALA C 1 409 ? -41.261 -74.672 -12.098 1.00 52.70  ? 409 ALA C CA  1 
ATOM 8627  C C   . ALA C 1 409 ? -40.649 -75.840 -12.880 1.00 51.31  ? 409 ALA C C   1 
ATOM 8628  O O   . ALA C 1 409 ? -39.942 -75.576 -13.870 1.00 61.10  ? 409 ALA C O   1 
ATOM 8629  C CB  . ALA C 1 409 ? -40.500 -74.395 -10.826 1.00 53.68  ? 409 ALA C CB  1 
ATOM 8630  N N   . ARG C 1 410 ? -40.922 -77.078 -12.454 1.00 48.45  ? 410 ARG C N   1 
ATOM 8631  C CA  . ARG C 1 410 ? -40.362 -78.275 -13.119 1.00 62.31  ? 410 ARG C CA  1 
ATOM 8632  C C   . ARG C 1 410 ? -40.997 -78.449 -14.489 1.00 72.69  ? 410 ARG C C   1 
ATOM 8633  O O   . ARG C 1 410 ? -40.268 -78.736 -15.420 1.00 76.26  ? 410 ARG C O   1 
ATOM 8634  C CB  . ARG C 1 410 ? -40.713 -79.526 -12.312 1.00 57.53  ? 410 ARG C CB  1 
ATOM 8635  C CG  . ARG C 1 410 ? -40.120 -80.818 -12.856 1.00 82.95  ? 410 ARG C CG  1 
ATOM 8636  C CD  . ARG C 1 410 ? -41.154 -81.913 -13.033 1.00 90.16  ? 410 ARG C CD  1 
ATOM 8637  N NE  . ARG C 1 410 ? -40.549 -83.236 -13.053 1.00 95.13  ? 410 ARG C NE  1 
ATOM 8638  C CZ  . ARG C 1 410 ? -41.210 -84.370 -13.265 1.00 90.13  ? 410 ARG C CZ  1 
ATOM 8639  N NH1 . ARG C 1 410 ? -42.511 -84.346 -13.495 1.00 80.55  ? 410 ARG C NH1 1 
ATOM 8640  N NH2 . ARG C 1 410 ? -40.564 -85.521 -13.254 1.00 81.82  ? 410 ARG C NH2 1 
ATOM 8641  N N   . GLU C 1 411 ? -42.312 -78.289 -14.587 1.00 70.25  ? 411 GLU C N   1 
ATOM 8642  C CA  . GLU C 1 411 ? -43.009 -78.519 -15.873 1.00 64.58  ? 411 GLU C CA  1 
ATOM 8643  C C   . GLU C 1 411 ? -42.515 -77.484 -16.885 1.00 59.98  ? 411 GLU C C   1 
ATOM 8644  O O   . GLU C 1 411 ? -42.194 -77.853 -18.031 1.00 64.32  ? 411 GLU C O   1 
ATOM 8645  C CB  . GLU C 1 411 ? -44.518 -78.501 -15.643 1.00 71.37  ? 411 GLU C CB  1 
ATOM 8646  C CG  . GLU C 1 411 ? -45.048 -79.804 -15.077 1.00 80.15  ? 411 GLU C CG  1 
ATOM 8647  C CD  . GLU C 1 411 ? -46.524 -79.783 -14.725 1.00 90.42  ? 411 GLU C CD  1 
ATOM 8648  O OE1 . GLU C 1 411 ? -47.095 -78.682 -14.658 1.00 83.23  ? 411 GLU C OE1 1 
ATOM 8649  O OE2 . GLU C 1 411 ? -47.099 -80.870 -14.521 1.00 90.32  ? 411 GLU C OE2 1 
ATOM 8650  N N   . LEU C 1 412 ? -42.381 -76.243 -16.437 1.00 55.94  ? 412 LEU C N   1 
ATOM 8651  C CA  . LEU C 1 412 ? -41.902 -75.178 -17.344 1.00 60.11  ? 412 LEU C CA  1 
ATOM 8652  C C   . LEU C 1 412 ? -40.455 -75.454 -17.756 1.00 61.95  ? 412 LEU C C   1 
ATOM 8653  O O   . LEU C 1 412 ? -40.129 -75.161 -18.899 1.00 60.23  ? 412 LEU C O   1 
ATOM 8654  C CB  . LEU C 1 412 ? -42.116 -73.812 -16.691 1.00 57.18  ? 412 LEU C CB  1 
ATOM 8655  C CG  . LEU C 1 412 ? -43.571 -73.352 -16.647 1.00 76.69  ? 412 LEU C CG  1 
ATOM 8656  C CD1 . LEU C 1 412 ? -43.657 -71.849 -16.462 1.00 68.52  ? 412 LEU C CD1 1 
ATOM 8657  C CD2 . LEU C 1 412 ? -44.307 -73.757 -17.914 1.00 66.28  ? 412 LEU C CD2 1 
ATOM 8658  N N   . SER C 1 413 ? -39.624 -75.972 -16.849 1.00 65.46  ? 413 SER C N   1 
ATOM 8659  C CA  . SER C 1 413 ? -38.208 -76.309 -17.150 1.00 61.72  ? 413 SER C CA  1 
ATOM 8660  C C   . SER C 1 413 ? -38.166 -77.414 -18.192 1.00 58.72  ? 413 SER C C   1 
ATOM 8661  O O   . SER C 1 413 ? -37.369 -77.325 -19.136 1.00 62.80  ? 413 SER C O   1 
ATOM 8662  C CB  . SER C 1 413 ? -37.489 -76.741 -15.910 1.00 65.14  ? 413 SER C CB  1 
ATOM 8663  O OG  . SER C 1 413 ? -36.185 -77.206 -16.220 1.00 76.81  ? 413 SER C OG  1 
ATOM 8664  N N   . GLU C 1 414 ? -39.050 -78.392 -18.036 1.00 60.27  ? 414 GLU C N   1 
ATOM 8665  C CA  . GLU C 1 414 ? -39.109 -79.501 -19.003 1.00 69.06  ? 414 GLU C CA  1 
ATOM 8666  C C   . GLU C 1 414 ? -39.478 -78.903 -20.351 1.00 66.14  ? 414 GLU C C   1 
ATOM 8667  O O   . GLU C 1 414 ? -38.864 -79.294 -21.327 1.00 73.79  ? 414 GLU C O   1 
ATOM 8668  C CB  . GLU C 1 414 ? -40.143 -80.530 -18.553 1.00 67.75  ? 414 GLU C CB  1 
ATOM 8669  C CG  . GLU C 1 414 ? -39.675 -81.386 -17.394 1.00 69.58  ? 414 GLU C CG  1 
ATOM 8670  C CD  . GLU C 1 414 ? -40.720 -82.353 -16.873 1.00 89.91  ? 414 GLU C CD  1 
ATOM 8671  O OE1 . GLU C 1 414 ? -41.919 -82.036 -16.973 1.00 73.18  ? 414 GLU C OE1 1 
ATOM 8672  O OE2 . GLU C 1 414 ? -40.331 -83.427 -16.379 1.00 107.67 ? 414 GLU C OE2 1 
ATOM 8673  N N   . LYS C 1 415 ? -40.426 -77.969 -20.372 1.00 57.01  ? 415 LYS C N   1 
ATOM 8674  C CA  . LYS C 1 415 ? -40.864 -77.375 -21.657 1.00 58.14  ? 415 LYS C CA  1 
ATOM 8675  C C   . LYS C 1 415 ? -39.706 -76.605 -22.277 1.00 59.30  ? 415 LYS C C   1 
ATOM 8676  O O   . LYS C 1 415 ? -39.489 -76.740 -23.481 1.00 67.33  ? 415 LYS C O   1 
ATOM 8677  C CB  . LYS C 1 415 ? -42.036 -76.420 -21.449 1.00 56.76  ? 415 LYS C CB  1 
ATOM 8678  C CG  . LYS C 1 415 ? -43.412 -77.066 -21.419 1.00 62.48  ? 415 LYS C CG  1 
ATOM 8679  C CD  . LYS C 1 415 ? -44.471 -76.175 -20.811 1.00 71.32  ? 415 LYS C CD  1 
ATOM 8680  C CE  . LYS C 1 415 ? -45.856 -76.770 -20.906 1.00 74.27  ? 415 LYS C CE  1 
ATOM 8681  N NZ  . LYS C 1 415 ? -45.862 -78.198 -20.507 1.00 86.36  ? 415 LYS C NZ  1 
ATOM 8682  N N   . MET C 1 416 ? -38.977 -75.855 -21.469 1.00 58.78  ? 416 MET C N   1 
ATOM 8683  C CA  . MET C 1 416 ? -37.906 -74.999 -22.019 1.00 60.61  ? 416 MET C CA  1 
ATOM 8684  C C   . MET C 1 416 ? -36.870 -75.920 -22.642 1.00 67.66  ? 416 MET C C   1 
ATOM 8685  O O   . MET C 1 416 ? -36.233 -75.516 -23.620 1.00 78.87  ? 416 MET C O   1 
ATOM 8686  C CB  . MET C 1 416 ? -37.306 -74.140 -20.906 1.00 56.31  ? 416 MET C CB  1 
ATOM 8687  C CG  . MET C 1 416 ? -38.237 -73.045 -20.435 1.00 65.13  ? 416 MET C CG  1 
ATOM 8688  S SD  . MET C 1 416 ? -37.646 -72.245 -18.933 1.00 57.45  ? 416 MET C SD  1 
ATOM 8689  C CE  . MET C 1 416 ? -36.086 -71.588 -19.514 1.00 44.50  ? 416 MET C CE  1 
ATOM 8690  N N   . LYS C 1 417 ? -36.726 -77.114 -22.093 1.00 64.05  ? 417 LYS C N   1 
ATOM 8691  C CA  . LYS C 1 417 ? -35.838 -78.098 -22.689 1.00 66.35  ? 417 LYS C CA  1 
ATOM 8692  C C   . LYS C 1 417 ? -36.552 -79.058 -23.629 1.00 65.98  ? 417 LYS C C   1 
ATOM 8693  O O   . LYS C 1 417 ? -35.884 -79.741 -24.414 1.00 69.36  ? 417 LYS C O   1 
ATOM 8694  C CB  . LYS C 1 417 ? -35.119 -78.898 -21.598 1.00 62.28  ? 417 LYS C CB  1 
ATOM 8695  C CG  . LYS C 1 417 ? -34.223 -78.055 -20.704 1.00 72.91  ? 417 LYS C CG  1 
ATOM 8696  C CD  . LYS C 1 417 ? -33.143 -77.342 -21.513 1.00 78.90  ? 417 LYS C CD  1 
ATOM 8697  C CE  . LYS C 1 417 ? -32.208 -78.333 -22.196 1.00 72.76  ? 417 LYS C CE  1 
ATOM 8698  N NZ  . LYS C 1 417 ? -31.135 -77.649 -22.970 1.00 74.00  ? 417 LYS C NZ  1 
ATOM 8699  N N   . GLU C 1 418 ? -37.884 -79.122 -23.575 1.00 66.30  ? 418 GLU C N   1 
ATOM 8700  C CA  . GLU C 1 418 ? -38.617 -79.996 -24.483 1.00 73.07  ? 418 GLU C CA  1 
ATOM 8701  C C   . GLU C 1 418 ? -38.664 -79.409 -25.890 1.00 76.87  ? 418 GLU C C   1 
ATOM 8702  O O   . GLU C 1 418 ? -38.407 -80.112 -26.873 1.00 84.17  ? 418 GLU C O   1 
ATOM 8703  C CB  . GLU C 1 418 ? -40.026 -80.251 -23.946 1.00 77.12  ? 418 GLU C CB  1 
ATOM 8704  C CG  . GLU C 1 418 ? -40.688 -81.495 -24.510 1.00 75.88  ? 418 GLU C CG  1 
ATOM 8705  C CD  . GLU C 1 418 ? -41.832 -81.988 -23.644 1.00 73.15  ? 418 GLU C CD  1 
ATOM 8706  O OE1 . GLU C 1 418 ? -42.222 -81.268 -22.701 1.00 78.91  ? 418 GLU C OE1 1 
ATOM 8707  O OE2 . GLU C 1 418 ? -42.338 -83.100 -23.907 1.00 70.08  ? 418 GLU C OE2 1 
ATOM 8708  N N   . LYS C 1 419 ? -38.779 -78.080 -25.974 1.00 73.95  ? 419 LYS C N   1 
ATOM 8709  C CA  . LYS C 1 419 ? -38.724 -77.388 -27.292 1.00 82.65  ? 419 LYS C CA  1 
ATOM 8710  C C   . LYS C 1 419 ? -37.305 -76.864 -27.505 1.00 86.03  ? 419 LYS C C   1 
ATOM 8711  O O   . LYS C 1 419 ? -37.157 -75.750 -28.030 1.00 88.27  ? 419 LYS C O   1 
ATOM 8712  C CB  . LYS C 1 419 ? -39.732 -76.237 -27.321 1.00 80.99  ? 419 LYS C CB  1 
ATOM 8713  C CG  . LYS C 1 419 ? -39.574 -75.186 -26.228 1.00 74.56  ? 419 LYS C CG  1 
ATOM 8714  C CD  . LYS C 1 419 ? -40.450 -73.974 -26.436 1.00 81.12  ? 419 LYS C CD  1 
ATOM 8715  C CE  . LYS C 1 419 ? -39.894 -72.728 -25.783 1.00 86.31  ? 419 LYS C CE  1 
ATOM 8716  N NZ  . LYS C 1 419 ? -39.619 -72.939 -24.344 1.00 82.22  ? 419 LYS C NZ  1 
ATOM 8717  N N   . GLY C 1 420 ? -36.299 -77.667 -27.176 1.00 74.08  ? 420 GLY C N   1 
ATOM 8718  C CA  . GLY C 1 420 ? -34.906 -77.181 -27.199 1.00 74.93  ? 420 GLY C CA  1 
ATOM 8719  C C   . GLY C 1 420 ? -34.273 -76.939 -28.546 1.00 86.98  ? 420 GLY C C   1 
ATOM 8720  O O   . GLY C 1 420 ? -34.537 -77.746 -29.446 1.00 93.58  ? 420 GLY C O   1 
ATOM 8721  N N   . GLU C 1 421 ? -33.539 -75.833 -28.695 1.00 83.23  ? 421 GLU C N   1 
ATOM 8722  C CA  . GLU C 1 421 ? -32.734 -75.530 -29.913 1.00 77.23  ? 421 GLU C CA  1 
ATOM 8723  C C   . GLU C 1 421 ? -33.579 -74.964 -31.050 1.00 74.86  ? 421 GLU C C   1 
ATOM 8724  O O   . GLU C 1 421 ? -33.038 -74.209 -31.852 1.00 74.92  ? 421 GLU C O   1 
ATOM 8725  C CB  . GLU C 1 421 ? -31.847 -76.704 -30.335 1.00 74.59  ? 421 GLU C CB  1 
ATOM 8726  C CG  . GLU C 1 421 ? -30.797 -77.090 -29.304 1.00 83.51  ? 421 GLU C CG  1 
ATOM 8727  C CD  . GLU C 1 421 ? -29.634 -76.137 -29.067 1.00 86.63  ? 421 GLU C CD  1 
ATOM 8728  O OE1 . GLU C 1 421 ? -29.843 -74.908 -29.077 1.00 70.90  ? 421 GLU C OE1 1 
ATOM 8729  O OE2 . GLU C 1 421 ? -28.513 -76.631 -28.848 1.00 90.63  ? 421 GLU C OE2 1 
ATOM 8730  N N   . GLN C 1 422 ? -34.873 -75.242 -31.045 1.00 75.71  ? 422 GLN C N   1 
ATOM 8731  C CA  . GLN C 1 422 ? -35.751 -74.776 -32.138 1.00 75.11  ? 422 GLN C CA  1 
ATOM 8732  C C   . GLN C 1 422 ? -35.849 -73.257 -32.122 1.00 71.25  ? 422 GLN C C   1 
ATOM 8733  O O   . GLN C 1 422 ? -35.849 -72.679 -33.202 1.00 69.40  ? 422 GLN C O   1 
ATOM 8734  C CB  . GLN C 1 422 ? -37.148 -75.373 -32.014 1.00 83.97  ? 422 GLN C CB  1 
ATOM 8735  C CG  . GLN C 1 422 ? -37.166 -76.796 -31.472 1.00 97.85  ? 422 GLN C CG  1 
ATOM 8736  C CD  . GLN C 1 422 ? -36.525 -77.799 -32.399 1.00 110.51 ? 422 GLN C CD  1 
ATOM 8737  O OE1 . GLN C 1 422 ? -36.509 -77.630 -33.616 1.00 107.23 ? 422 GLN C OE1 1 
ATOM 8738  N NE2 . GLN C 1 422 ? -35.999 -78.867 -31.822 1.00 102.03 ? 422 GLN C NE2 1 
ATOM 8739  N N   . GLU C 1 423 ? -35.945 -72.641 -30.947 1.00 66.29  ? 423 GLU C N   1 
ATOM 8740  C CA  . GLU C 1 423 ? -36.188 -71.176 -30.923 1.00 60.42  ? 423 GLU C CA  1 
ATOM 8741  C C   . GLU C 1 423 ? -35.032 -70.414 -31.557 1.00 59.48  ? 423 GLU C C   1 
ATOM 8742  O O   . GLU C 1 423 ? -35.306 -69.535 -32.372 1.00 53.92  ? 423 GLU C O   1 
ATOM 8743  C CB  . GLU C 1 423 ? -36.531 -70.703 -29.508 1.00 47.13  ? 423 GLU C CB  1 
ATOM 8744  C CG  . GLU C 1 423 ? -35.919 -71.523 -28.386 1.00 74.76  ? 423 GLU C CG  1 
ATOM 8745  C CD  . GLU C 1 423 ? -36.374 -71.096 -26.997 1.00 80.57  ? 423 GLU C CD  1 
ATOM 8746  O OE1 . GLU C 1 423 ? -37.288 -70.252 -26.909 1.00 75.40  ? 423 GLU C OE1 1 
ATOM 8747  O OE2 . GLU C 1 423 ? -35.818 -71.610 -26.004 1.00 72.55  ? 423 GLU C OE2 1 
ATOM 8748  N N   . ILE C 1 424 ? -33.802 -70.758 -31.207 1.00 57.07  ? 424 ILE C N   1 
ATOM 8749  C CA  . ILE C 1 424 ? -32.610 -70.132 -31.842 1.00 53.62  ? 424 ILE C CA  1 
ATOM 8750  C C   . ILE C 1 424 ? -32.517 -70.583 -33.302 1.00 57.04  ? 424 ILE C C   1 
ATOM 8751  O O   . ILE C 1 424 ? -32.066 -69.789 -34.128 1.00 50.22  ? 424 ILE C O   1 
ATOM 8752  C CB  . ILE C 1 424 ? -31.343 -70.391 -31.014 1.00 52.79  ? 424 ILE C CB  1 
ATOM 8753  C CG1 . ILE C 1 424 ? -31.628 -70.224 -29.520 1.00 54.39  ? 424 ILE C CG1 1 
ATOM 8754  C CG2 . ILE C 1 424 ? -30.205 -69.494 -31.466 1.00 53.61  ? 424 ILE C CG2 1 
ATOM 8755  C CD1 . ILE C 1 424 ? -30.394 -70.223 -28.659 1.00 56.28  ? 424 ILE C CD1 1 
ATOM 8756  N N   . ASP C 1 425 ? -32.907 -71.821 -33.596 1.00 55.88  ? 425 ASP C N   1 
ATOM 8757  C CA  . ASP C 1 425 ? -32.910 -72.313 -34.997 1.00 51.66  ? 425 ASP C CA  1 
ATOM 8758  C C   . ASP C 1 425 ? -33.889 -71.494 -35.837 1.00 54.87  ? 425 ASP C C   1 
ATOM 8759  O O   . ASP C 1 425 ? -33.522 -71.117 -36.954 1.00 53.24  ? 425 ASP C O   1 
ATOM 8760  C CB  . ASP C 1 425 ? -33.299 -73.788 -35.048 1.00 55.02  ? 425 ASP C CB  1 
ATOM 8761  C CG  . ASP C 1 425 ? -32.188 -74.753 -34.682 1.00 73.21  ? 425 ASP C CG  1 
ATOM 8762  O OD1 . ASP C 1 425 ? -31.155 -74.294 -34.177 1.00 74.20  ? 425 ASP C OD1 1 
ATOM 8763  O OD2 . ASP C 1 425 ? -32.377 -75.962 -34.902 1.00 78.05  ? 425 ASP C OD2 1 
ATOM 8764  N N   . ARG C 1 426 ? -35.087 -71.244 -35.321 1.00 54.87  ? 426 ARG C N   1 
ATOM 8765  C CA  . ARG C 1 426 ? -36.088 -70.403 -36.022 1.00 57.75  ? 426 ARG C CA  1 
ATOM 8766  C C   . ARG C 1 426 ? -35.580 -68.968 -36.117 1.00 52.86  ? 426 ARG C C   1 
ATOM 8767  O O   . ARG C 1 426 ? -35.909 -68.288 -37.093 1.00 57.05  ? 426 ARG C O   1 
ATOM 8768  C CB  . ARG C 1 426 ? -37.436 -70.514 -35.310 1.00 55.61  ? 426 ARG C CB  1 
ATOM 8769  C CG  . ARG C 1 426 ? -38.053 -71.903 -35.376 1.00 60.91  ? 426 ARG C CG  1 
ATOM 8770  C CD  . ARG C 1 426 ? -39.440 -71.952 -34.771 1.00 80.15  ? 426 ARG C CD  1 
ATOM 8771  N NE  . ARG C 1 426 ? -39.495 -71.212 -33.520 1.00 94.98  ? 426 ARG C NE  1 
ATOM 8772  C CZ  . ARG C 1 426 ? -40.578 -71.092 -32.764 1.00 88.71  ? 426 ARG C CZ  1 
ATOM 8773  N NH1 . ARG C 1 426 ? -41.708 -71.670 -33.133 1.00 91.38  ? 426 ARG C NH1 1 
ATOM 8774  N NH2 . ARG C 1 426 ? -40.527 -70.394 -31.642 1.00 63.19  ? 426 ARG C NH2 1 
ATOM 8775  N N   . ALA C 1 427 ? -34.884 -68.499 -35.086 1.00 51.61  ? 427 ALA C N   1 
ATOM 8776  C CA  . ALA C 1 427 ? -34.306 -67.141 -35.097 1.00 56.24  ? 427 ALA C CA  1 
ATOM 8777  C C   . ALA C 1 427 ? -33.258 -67.061 -36.194 1.00 57.52  ? 427 ALA C C   1 
ATOM 8778  O O   . ALA C 1 427 ? -33.223 -66.052 -36.897 1.00 57.59  ? 427 ALA C O   1 
ATOM 8779  C CB  . ALA C 1 427 ? -33.670 -66.868 -33.771 1.00 52.39  ? 427 ALA C CB  1 
ATOM 8780  N N   . VAL C 1 428 ? -32.435 -68.099 -36.316 1.00 51.83  ? 428 VAL C N   1 
ATOM 8781  C CA  . VAL C 1 428 ? -31.398 -68.091 -37.343 1.00 47.55  ? 428 VAL C CA  1 
ATOM 8782  C C   . VAL C 1 428 ? -32.019 -68.119 -38.731 1.00 58.91  ? 428 VAL C C   1 
ATOM 8783  O O   . VAL C 1 428 ? -31.574 -67.404 -39.638 1.00 59.41  ? 428 VAL C O   1 
ATOM 8784  C CB  . VAL C 1 428 ? -30.427 -69.266 -37.138 1.00 48.97  ? 428 VAL C CB  1 
ATOM 8785  C CG1 . VAL C 1 428 ? -29.530 -69.435 -38.356 1.00 48.52  ? 428 VAL C CG1 1 
ATOM 8786  C CG2 . VAL C 1 428 ? -29.593 -69.041 -35.903 1.00 62.95  ? 428 VAL C CG2 1 
ATOM 8787  N N   . GLU C 1 429 ? -33.043 -68.949 -38.930 1.00 55.56  ? 429 GLU C N   1 
ATOM 8788  C CA  . GLU C 1 429 ? -33.653 -68.987 -40.253 1.00 52.14  ? 429 GLU C CA  1 
ATOM 8789  C C   . GLU C 1 429 ? -34.359 -67.670 -40.572 1.00 58.48  ? 429 GLU C C   1 
ATOM 8790  O O   . GLU C 1 429 ? -34.360 -67.242 -41.729 1.00 60.11  ? 429 GLU C O   1 
ATOM 8791  C CB  . GLU C 1 429 ? -34.605 -70.175 -40.392 1.00 53.37  ? 429 GLU C CB  1 
ATOM 8792  C CG  . GLU C 1 429 ? -35.868 -70.109 -39.568 1.00 65.53  ? 429 GLU C CG  1 
ATOM 8793  C CD  . GLU C 1 429 ? -36.732 -71.343 -39.733 1.00 77.12  ? 429 GLU C CD  1 
ATOM 8794  O OE1 . GLU C 1 429 ? -36.643 -72.005 -40.790 1.00 86.54  ? 429 GLU C OE1 1 
ATOM 8795  O OE2 . GLU C 1 429 ? -37.499 -71.657 -38.799 1.00 82.43  ? 429 GLU C OE2 1 
ATOM 8796  N N   . GLU C 1 430 ? -34.909 -66.982 -39.566 1.00 55.23  ? 430 GLU C N   1 
ATOM 8797  C CA  . GLU C 1 430 ? -35.504 -65.678 -39.844 1.00 60.44  ? 430 GLU C CA  1 
ATOM 8798  C C   . GLU C 1 430 ? -34.441 -64.619 -40.120 1.00 58.02  ? 430 GLU C C   1 
ATOM 8799  O O   . GLU C 1 430 ? -34.656 -63.737 -40.959 1.00 58.18  ? 430 GLU C O   1 
ATOM 8800  C CB  . GLU C 1 430 ? -36.423 -65.239 -38.701 1.00 64.46  ? 430 GLU C CB  1 
ATOM 8801  C CG  . GLU C 1 430 ? -37.564 -64.326 -39.160 1.00 67.40  ? 430 GLU C CG  1 
ATOM 8802  C CD  . GLU C 1 430 ? -38.839 -64.507 -38.343 1.00 65.09  ? 430 GLU C CD  1 
ATOM 8803  O OE1 . GLU C 1 430 ? -38.743 -64.910 -37.161 1.00 62.71  ? 430 GLU C OE1 1 
ATOM 8804  O OE2 . GLU C 1 430 ? -39.942 -64.247 -38.883 1.00 66.69  ? 430 GLU C OE2 1 
ATOM 8805  N N   . LEU C 1 431 ? -33.288 -64.696 -39.449 1.00 56.68  ? 431 LEU C N   1 
ATOM 8806  C CA  . LEU C 1 431 ? -32.192 -63.787 -39.786 1.00 51.12  ? 431 LEU C CA  1 
ATOM 8807  C C   . LEU C 1 431 ? -31.720 -64.004 -41.221 1.00 55.21  ? 431 LEU C C   1 
ATOM 8808  O O   . LEU C 1 431 ? -31.476 -63.042 -41.962 1.00 48.81  ? 431 LEU C O   1 
ATOM 8809  C CB  . LEU C 1 431 ? -31.033 -63.970 -38.807 1.00 46.86  ? 431 LEU C CB  1 
ATOM 8810  C CG  . LEU C 1 431 ? -31.211 -63.404 -37.395 1.00 51.11  ? 431 LEU C CG  1 
ATOM 8811  C CD1 . LEU C 1 431 ? -30.153 -63.950 -36.442 1.00 44.69  ? 431 LEU C CD1 1 
ATOM 8812  C CD2 . LEU C 1 431 ? -31.175 -61.882 -37.410 1.00 49.61  ? 431 LEU C CD2 1 
ATOM 8813  N N   . VAL C 1 432 ? -31.590 -65.269 -41.630 1.00 55.16  ? 432 VAL C N   1 
ATOM 8814  C CA  . VAL C 1 432 ? -31.228 -65.570 -43.012 1.00 53.36  ? 432 VAL C CA  1 
ATOM 8815  C C   . VAL C 1 432 ? -32.303 -65.073 -43.968 1.00 57.88  ? 432 VAL C C   1 
ATOM 8816  O O   . VAL C 1 432 ? -32.003 -64.627 -45.083 1.00 53.41  ? 432 VAL C O   1 
ATOM 8817  C CB  . VAL C 1 432 ? -30.970 -67.081 -43.178 1.00 47.82  ? 432 VAL C CB  1 
ATOM 8818  C CG1 . VAL C 1 432 ? -30.674 -67.425 -44.631 1.00 42.73  ? 432 VAL C CG1 1 
ATOM 8819  C CG2 . VAL C 1 432 ? -29.820 -67.517 -42.289 1.00 38.38  ? 432 VAL C CG2 1 
ATOM 8820  N N   . GLN C 1 433 ? -33.571 -65.138 -43.554 1.00 62.89  ? 433 GLN C N   1 
ATOM 8821  C CA  . GLN C 1 433 ? -34.638 -64.556 -44.358 1.00 61.67  ? 433 GLN C CA  1 
ATOM 8822  C C   . GLN C 1 433 ? -34.442 -63.053 -44.517 1.00 59.32  ? 433 GLN C C   1 
ATOM 8823  O O   . GLN C 1 433 ? -34.657 -62.505 -45.603 1.00 62.50  ? 433 GLN C O   1 
ATOM 8824  C CB  . GLN C 1 433 ? -35.998 -64.861 -43.730 1.00 69.29  ? 433 GLN C CB  1 
ATOM 8825  C CG  . GLN C 1 433 ? -37.185 -64.329 -44.519 1.00 79.05  ? 433 GLN C CG  1 
ATOM 8826  C CD  . GLN C 1 433 ? -38.516 -64.697 -43.889 1.00 87.40  ? 433 GLN C CD  1 
ATOM 8827  O OE1 . GLN C 1 433 ? -38.563 -65.360 -42.852 1.00 77.83  ? 433 GLN C OE1 1 
ATOM 8828  N NE2 . GLN C 1 433 ? -39.607 -64.269 -44.515 1.00 90.07  ? 433 GLN C NE2 1 
ATOM 8829  N N   . ILE C 1 434 ? -34.038 -62.368 -43.446 1.00 60.78  ? 434 ILE C N   1 
ATOM 8830  C CA  . ILE C 1 434 ? -33.754 -60.936 -43.551 1.00 61.87  ? 434 ILE C CA  1 
ATOM 8831  C C   . ILE C 1 434 ? -32.641 -60.701 -44.568 1.00 60.97  ? 434 ILE C C   1 
ATOM 8832  O O   . ILE C 1 434 ? -32.743 -59.831 -45.447 1.00 60.99  ? 434 ILE C O   1 
ATOM 8833  C CB  . ILE C 1 434 ? -33.388 -60.344 -42.178 1.00 58.18  ? 434 ILE C CB  1 
ATOM 8834  C CG1 . ILE C 1 434 ? -34.504 -60.589 -41.162 1.00 61.87  ? 434 ILE C CG1 1 
ATOM 8835  C CG2 . ILE C 1 434 ? -33.105 -58.853 -42.302 1.00 49.95  ? 434 ILE C CG2 1 
ATOM 8836  C CD1 . ILE C 1 434 ? -35.878 -60.240 -41.675 1.00 68.68  ? 434 ILE C CD1 1 
ATOM 8837  N N   . CYS C 1 435 ? -31.571 -61.493 -44.471 1.00 66.22  ? 435 CYS C N   1 
ATOM 8838  C CA  . CYS C 1 435 ? -30.439 -61.313 -45.376 1.00 64.01  ? 435 CYS C CA  1 
ATOM 8839  C C   . CYS C 1 435 ? -30.837 -61.546 -46.832 1.00 62.73  ? 435 CYS C C   1 
ATOM 8840  O O   . CYS C 1 435 ? -30.409 -60.804 -47.723 1.00 65.77  ? 435 CYS C O   1 
ATOM 8841  C CB  . CYS C 1 435 ? -29.288 -62.235 -44.970 1.00 65.72  ? 435 CYS C CB  1 
ATOM 8842  S SG  . CYS C 1 435 ? -28.396 -61.686 -43.496 1.00 53.81  ? 435 CYS C SG  1 
ATOM 8843  N N   . LYS C 1 436 ? -31.664 -62.563 -47.093 1.00 59.46  ? 436 LYS C N   1 
ATOM 8844  C CA  . LYS C 1 436 ? -32.079 -62.816 -48.473 1.00 65.69  ? 436 LYS C CA  1 
ATOM 8845  C C   . LYS C 1 436 ? -33.088 -61.782 -48.956 1.00 62.48  ? 436 LYS C C   1 
ATOM 8846  O O   . LYS C 1 436 ? -33.165 -61.509 -50.159 1.00 60.51  ? 436 LYS C O   1 
ATOM 8847  C CB  . LYS C 1 436 ? -32.653 -64.228 -48.616 1.00 61.48  ? 436 LYS C CB  1 
ATOM 8848  C CG  . LYS C 1 436 ? -34.017 -64.410 -47.982 1.00 64.64  ? 436 LYS C CG  1 
ATOM 8849  C CD  . LYS C 1 436 ? -34.686 -65.699 -48.417 1.00 75.15  ? 436 LYS C CD  1 
ATOM 8850  C CE  . LYS C 1 436 ? -36.016 -65.882 -47.688 1.00 76.46  ? 436 LYS C CE  1 
ATOM 8851  N NZ  . LYS C 1 436 ? -36.920 -64.710 -47.868 1.00 70.62  ? 436 LYS C NZ  1 
ATOM 8852  N N   . LYS C 1 437 ? -33.866 -61.155 -48.087 1.00 59.61  ? 437 LYS C N   1 
ATOM 8853  C CA  . LYS C 1 437 ? -34.781 -60.123 -48.631 1.00 58.13  ? 437 LYS C CA  1 
ATOM 8854  C C   . LYS C 1 437 ? -33.928 -58.943 -49.074 1.00 60.31  ? 437 LYS C C   1 
ATOM 8855  O O   . LYS C 1 437 ? -34.427 -58.103 -49.830 1.00 66.37  ? 437 LYS C O   1 
ATOM 8856  C CB  . LYS C 1 437 ? -35.809 -59.685 -47.589 1.00 55.05  ? 437 LYS C CB  1 
ATOM 8857  C CG  . LYS C 1 437 ? -36.978 -58.860 -48.111 1.00 62.18  ? 437 LYS C CG  1 
ATOM 8858  C CD  . LYS C 1 437 ? -37.822 -58.254 -47.012 1.00 76.02  ? 437 LYS C CD  1 
ATOM 8859  C CE  . LYS C 1 437 ? -37.039 -57.324 -46.110 1.00 81.60  ? 437 LYS C CE  1 
ATOM 8860  N NZ  . LYS C 1 437 ? -36.535 -56.138 -46.840 1.00 72.70  ? 437 LYS C NZ  1 
ATOM 8861  N N   . LYS C 1 438 ? -32.679 -58.899 -48.619 1.00 64.48  ? 438 LYS C N   1 
ATOM 8862  C CA  . LYS C 1 438 ? -31.784 -57.762 -48.963 1.00 72.08  ? 438 LYS C CA  1 
ATOM 8863  C C   . LYS C 1 438 ? -30.986 -58.101 -50.220 1.00 69.44  ? 438 LYS C C   1 
ATOM 8864  O O   . LYS C 1 438 ? -30.225 -57.245 -50.685 1.00 63.07  ? 438 LYS C O   1 
ATOM 8865  C CB  . LYS C 1 438 ? -30.931 -57.355 -47.760 1.00 60.76  ? 438 LYS C CB  1 
ATOM 8866  C CG  . LYS C 1 438 ? -31.682 -56.652 -46.638 1.00 69.29  ? 438 LYS C CG  1 
ATOM 8867  C CD  . LYS C 1 438 ? -31.927 -55.189 -46.925 1.00 67.02  ? 438 LYS C CD  1 
ATOM 8868  C CE  . LYS C 1 438 ? -30.646 -54.420 -47.166 1.00 61.94  ? 438 LYS C CE  1 
ATOM 8869  N NZ  . LYS C 1 438 ? -30.896 -52.968 -47.311 1.00 59.34  ? 438 LYS C NZ  1 
ATOM 8870  N N   . LYS C 1 439 ? -31.164 -59.304 -50.754 1.00 73.87  ? 439 LYS C N   1 
ATOM 8871  C CA  . LYS C 1 439 ? -30.516 -59.644 -52.040 1.00 70.43  ? 439 LYS C CA  1 
ATOM 8872  C C   . LYS C 1 439 ? -31.419 -59.093 -53.135 1.00 78.91  ? 439 LYS C C   1 
ATOM 8873  O O   . LYS C 1 439 ? -32.075 -59.891 -53.814 1.00 80.85  ? 439 LYS C O   1 
ATOM 8874  C CB  . LYS C 1 439 ? -30.370 -61.159 -52.174 1.00 79.69  ? 439 LYS C CB  1 
ATOM 8875  C CG  . LYS C 1 439 ? -29.236 -61.772 -51.366 1.00 67.90  ? 439 LYS C CG  1 
ATOM 8876  C CD  . LYS C 1 439 ? -27.892 -61.169 -51.706 1.00 81.83  ? 439 LYS C CD  1 
ATOM 8877  C CE  . LYS C 1 439 ? -27.520 -61.318 -53.165 1.00 90.55  ? 439 LYS C CE  1 
ATOM 8878  N NZ  . LYS C 1 439 ? -26.302 -60.544 -53.497 1.00 77.20  ? 439 LYS C NZ  1 
ATOM 8879  N N   . ASP C 1 440 ? -31.475 -57.768 -53.261 1.00 84.76  ? 440 ASP C N   1 
ATOM 8880  C CA  . ASP C 1 440 ? -32.285 -57.111 -54.314 1.00 80.28  ? 440 ASP C CA  1 
ATOM 8881  C C   . ASP C 1 440 ? -31.302 -56.410 -55.249 1.00 78.96  ? 440 ASP C C   1 
ATOM 8882  O O   . ASP C 1 440 ? -30.436 -55.689 -54.737 1.00 74.56  ? 440 ASP C O   1 
ATOM 8883  C CB  . ASP C 1 440 ? -33.334 -56.175 -53.714 1.00 73.55  ? 440 ASP C CB  1 
ATOM 8884  C CG  . ASP C 1 440 ? -32.911 -55.431 -52.456 1.00 81.71  ? 440 ASP C CG  1 
ATOM 8885  O OD1 . ASP C 1 440 ? -31.728 -55.060 -52.355 1.00 86.34  ? 440 ASP C OD1 1 
ATOM 8886  O OD2 . ASP C 1 440 ? -33.775 -55.222 -51.585 1.00 86.74  ? 440 ASP C OD2 1 
ATOM 8887  N N   . GLU C 1 441 ? -31.416 -56.642 -56.557 1.00 88.29  ? 441 GLU C N   1 
ATOM 8888  C CA  . GLU C 1 441 ? -30.444 -56.082 -57.525 1.00 88.20  ? 441 GLU C CA  1 
ATOM 8889  C C   . GLU C 1 441 ? -29.030 -56.520 -57.146 1.00 97.29  ? 441 GLU C C   1 
ATOM 8890  O O   . GLU C 1 441 ? -28.139 -55.657 -57.183 1.00 103.54 ? 441 GLU C O   1 
ATOM 8891  C CB  . GLU C 1 441 ? -30.544 -54.562 -57.587 1.00 83.27  ? 441 GLU C CB  1 
ATOM 8892  C CG  . GLU C 1 441 ? -31.969 -54.049 -57.728 1.00 98.28  ? 441 GLU C CG  1 
ATOM 8893  C CD  . GLU C 1 441 ? -32.641 -54.304 -59.065 1.00 86.74  ? 441 GLU C CD  1 
ATOM 8894  O OE1 . GLU C 1 441 ? -33.004 -55.466 -59.337 1.00 76.36  ? 441 GLU C OE1 1 
ATOM 8895  O OE2 . GLU C 1 441 ? -32.811 -53.332 -59.828 1.00 85.92  ? 441 GLU C OE2 1 
ATOM 8896  N N   . GLN C 1 442 ? -28.843 -57.788 -56.760 1.00 95.22  ? 442 GLN C N   1 
ATOM 8897  C CA  . GLN C 1 442 ? -27.487 -58.343 -56.483 1.00 91.11  ? 442 GLN C CA  1 
ATOM 8898  C C   . GLN C 1 442 ? -26.735 -57.483 -55.465 1.00 87.32  ? 442 GLN C C   1 
ATOM 8899  O O   . GLN C 1 442 ? -25.771 -58.018 -54.885 1.00 91.18  ? 442 GLN C O   1 
ATOM 8900  C CB  . GLN C 1 442 ? -26.692 -58.486 -57.782 1.00 96.06  ? 442 GLN C CB  1 
ATOM 8901  C CG  . GLN C 1 442 ? -27.335 -59.420 -58.795 1.00 99.86  ? 442 GLN C CG  1 
ATOM 8902  C CD  . GLN C 1 442 ? -28.007 -58.670 -59.919 1.00 96.03  ? 442 GLN C CD  1 
ATOM 8903  O OE1 . GLN C 1 442 ? -27.830 -57.466 -60.082 1.00 93.52  ? 442 GLN C OE1 1 
ATOM 8904  N NE2 . GLN C 1 442 ? -28.788 -59.384 -60.712 1.00 86.88  ? 442 GLN C NE2 1 
ATOM 8905  N N   . ILE D 1 8   ? -13.591 -72.137 70.495  1.00 57.53  ? 8   ILE D N   1 
ATOM 8906  C CA  . ILE D 1 8   ? -14.432 -72.931 69.609  1.00 58.00  ? 8   ILE D CA  1 
ATOM 8907  C C   . ILE D 1 8   ? -15.330 -72.031 68.757  1.00 55.90  ? 8   ILE D C   1 
ATOM 8908  O O   . ILE D 1 8   ? -15.513 -72.283 67.569  1.00 64.10  ? 8   ILE D O   1 
ATOM 8909  C CB  . ILE D 1 8   ? -15.274 -73.949 70.411  1.00 53.80  ? 8   ILE D CB  1 
ATOM 8910  C CG1 . ILE D 1 8   ? -14.366 -74.850 71.255  1.00 62.08  ? 8   ILE D CG1 1 
ATOM 8911  C CG2 . ILE D 1 8   ? -16.126 -74.796 69.475  1.00 60.14  ? 8   ILE D CG2 1 
ATOM 8912  C CD1 . ILE D 1 8   ? -13.424 -75.711 70.439  1.00 64.39  ? 8   ILE D CD1 1 
ATOM 8913  N N   . SER D 1 9   ? -15.884 -70.981 69.359  1.00 48.93  ? 9   SER D N   1 
ATOM 8914  C CA  . SER D 1 9   ? -16.773 -70.063 68.659  1.00 52.48  ? 9   SER D CA  1 
ATOM 8915  C C   . SER D 1 9   ? -16.009 -68.839 68.176  1.00 56.52  ? 9   SER D C   1 
ATOM 8916  O O   . SER D 1 9   ? -15.207 -68.258 68.917  1.00 58.32  ? 9   SER D O   1 
ATOM 8917  C CB  . SER D 1 9   ? -17.930 -69.621 69.558  1.00 49.18  ? 9   SER D CB  1 
ATOM 8918  O OG  . SER D 1 9   ? -17.489 -68.685 70.524  1.00 51.31  ? 9   SER D OG  1 
ATOM 8919  N N   . ILE D 1 10  ? -16.266 -68.441 66.929  1.00 49.71  ? 10  ILE D N   1 
ATOM 8920  C CA  . ILE D 1 10  ? -15.583 -67.323 66.291  1.00 48.40  ? 10  ILE D CA  1 
ATOM 8921  C C   . ILE D 1 10  ? -16.619 -66.399 65.664  1.00 42.79  ? 10  ILE D C   1 
ATOM 8922  O O   . ILE D 1 10  ? -17.644 -66.863 65.146  1.00 48.57  ? 10  ILE D O   1 
ATOM 8923  C CB  . ILE D 1 10  ? -14.574 -67.805 65.221  1.00 46.93  ? 10  ILE D CB  1 
ATOM 8924  C CG1 . ILE D 1 10  ? -13.673 -68.908 65.778  1.00 47.98  ? 10  ILE D CG1 1 
ATOM 8925  C CG2 . ILE D 1 10  ? -13.722 -66.648 64.718  1.00 46.66  ? 10  ILE D CG2 1 
ATOM 8926  C CD1 . ILE D 1 10  ? -12.663 -69.428 64.781  1.00 49.87  ? 10  ILE D CD1 1 
ATOM 8927  N N   . ALA D 1 11  ? -16.354 -65.095 65.712  1.00 40.04  ? 11  ALA D N   1 
ATOM 8928  C CA  . ALA D 1 11  ? -17.185 -64.084 65.076  1.00 38.12  ? 11  ALA D CA  1 
ATOM 8929  C C   . ALA D 1 11  ? -16.355 -63.314 64.059  1.00 41.21  ? 11  ALA D C   1 
ATOM 8930  O O   . ALA D 1 11  ? -15.210 -62.942 64.334  1.00 44.21  ? 11  ALA D O   1 
ATOM 8931  C CB  . ALA D 1 11  ? -17.778 -63.121 66.111  1.00 39.18  ? 11  ALA D CB  1 
ATOM 8932  N N   . LEU D 1 12  ? -16.931 -63.077 62.884  1.00 42.81  ? 12  LEU D N   1 
ATOM 8933  C CA  . LEU D 1 12  ? -16.247 -62.424 61.777  1.00 42.50  ? 12  LEU D CA  1 
ATOM 8934  C C   . LEU D 1 12  ? -16.922 -61.098 61.466  1.00 42.05  ? 12  LEU D C   1 
ATOM 8935  O O   . LEU D 1 12  ? -18.154 -61.022 61.381  1.00 51.13  ? 12  LEU D O   1 
ATOM 8936  C CB  . LEU D 1 12  ? -16.237 -63.314 60.529  1.00 35.37  ? 12  LEU D CB  1 
ATOM 8937  C CG  . LEU D 1 12  ? -14.974 -64.147 60.302  1.00 40.29  ? 12  LEU D CG  1 
ATOM 8938  C CD1 . LEU D 1 12  ? -14.681 -65.007 61.515  1.00 51.07  ? 12  LEU D CD1 1 
ATOM 8939  C CD2 . LEU D 1 12  ? -15.101 -65.002 59.051  1.00 46.67  ? 12  LEU D CD2 1 
ATOM 8940  N N   . LEU D 1 13  ? -16.110 -60.053 61.306  1.00 38.00  ? 13  LEU D N   1 
ATOM 8941  C CA  . LEU D 1 13  ? -16.585 -58.708 60.988  1.00 36.79  ? 13  LEU D CA  1 
ATOM 8942  C C   . LEU D 1 13  ? -15.803 -58.197 59.784  1.00 40.91  ? 13  LEU D C   1 
ATOM 8943  O O   . LEU D 1 13  ? -14.816 -57.464 59.933  1.00 37.85  ? 13  LEU D O   1 
ATOM 8944  C CB  . LEU D 1 13  ? -16.433 -57.767 62.181  1.00 34.35  ? 13  LEU D CB  1 
ATOM 8945  C CG  . LEU D 1 13  ? -16.943 -56.340 61.984  1.00 40.89  ? 13  LEU D CG  1 
ATOM 8946  C CD1 . LEU D 1 13  ? -18.454 -56.271 62.166  1.00 39.95  ? 13  LEU D CD1 1 
ATOM 8947  C CD2 . LEU D 1 13  ? -16.233 -55.383 62.928  1.00 44.98  ? 13  LEU D CD2 1 
ATOM 8948  N N   . PRO D 1 14  ? -16.211 -58.577 58.577  1.00 39.17  ? 14  PRO D N   1 
ATOM 8949  C CA  . PRO D 1 14  ? -15.575 -58.025 57.376  1.00 45.12  ? 14  PRO D CA  1 
ATOM 8950  C C   . PRO D 1 14  ? -15.968 -56.570 57.172  1.00 46.37  ? 14  PRO D C   1 
ATOM 8951  O O   . PRO D 1 14  ? -16.789 -56.003 57.896  1.00 51.16  ? 14  PRO D O   1 
ATOM 8952  C CB  . PRO D 1 14  ? -16.114 -58.911 56.252  1.00 43.49  ? 14  PRO D CB  1 
ATOM 8953  C CG  . PRO D 1 14  ? -17.424 -59.407 56.771  1.00 42.05  ? 14  PRO D CG  1 
ATOM 8954  C CD  . PRO D 1 14  ? -17.245 -59.571 58.250  1.00 44.88  ? 14  PRO D CD  1 
ATOM 8955  N N   . PHE D 1 15  ? -15.362 -55.961 56.160  1.00 47.76  ? 15  PHE D N   1 
ATOM 8956  C CA  . PHE D 1 15  ? -15.700 -54.592 55.811  1.00 60.33  ? 15  PHE D CA  1 
ATOM 8957  C C   . PHE D 1 15  ? -16.879 -54.573 54.837  1.00 63.68  ? 15  PHE D C   1 
ATOM 8958  O O   . PHE D 1 15  ? -17.291 -55.603 54.293  1.00 58.10  ? 15  PHE D O   1 
ATOM 8959  C CB  . PHE D 1 15  ? -14.487 -53.871 55.224  1.00 51.30  ? 15  PHE D CB  1 
ATOM 8960  C CG  . PHE D 1 15  ? -14.648 -52.382 55.156  1.00 62.29  ? 15  PHE D CG  1 
ATOM 8961  C CD1 . PHE D 1 15  ? -15.188 -51.683 56.223  1.00 61.75  ? 15  PHE D CD1 1 
ATOM 8962  C CD2 . PHE D 1 15  ? -14.258 -51.680 54.030  1.00 63.28  ? 15  PHE D CD2 1 
ATOM 8963  C CE1 . PHE D 1 15  ? -15.344 -50.312 56.165  1.00 67.48  ? 15  PHE D CE1 1 
ATOM 8964  C CE2 . PHE D 1 15  ? -14.407 -50.306 53.967  1.00 63.74  ? 15  PHE D CE2 1 
ATOM 8965  C CZ  . PHE D 1 15  ? -14.952 -49.622 55.036  1.00 72.09  ? 15  PHE D CZ  1 
ATOM 8966  N N   . LEU D 1 16  ? -17.430 -53.381 54.624  1.00 57.72  ? 16  LEU D N   1 
ATOM 8967  C CA  . LEU D 1 16  ? -18.636 -53.213 53.811  1.00 61.04  ? 16  LEU D CA  1 
ATOM 8968  C C   . LEU D 1 16  ? -18.283 -53.104 52.327  1.00 67.38  ? 16  LEU D C   1 
ATOM 8969  O O   . LEU D 1 16  ? -18.512 -52.090 51.666  1.00 67.29  ? 16  LEU D O   1 
ATOM 8970  C CB  . LEU D 1 16  ? -19.426 -52.000 54.285  1.00 60.27  ? 16  LEU D CB  1 
ATOM 8971  C CG  . LEU D 1 16  ? -20.561 -52.298 55.263  1.00 57.91  ? 16  LEU D CG  1 
ATOM 8972  C CD1 . LEU D 1 16  ? -20.110 -53.278 56.332  1.00 71.20  ? 16  LEU D CD1 1 
ATOM 8973  C CD2 . LEU D 1 16  ? -21.064 -51.011 55.891  1.00 62.26  ? 16  LEU D CD2 1 
ATOM 8974  N N   . ALA D 1 17  ? -17.720 -54.189 51.806  1.00 75.65  ? 17  ALA D N   1 
ATOM 8975  C CA  . ALA D 1 17  ? -17.362 -54.272 50.400  1.00 68.24  ? 17  ALA D CA  1 
ATOM 8976  C C   . ALA D 1 17  ? -17.380 -55.735 49.989  1.00 73.29  ? 17  ALA D C   1 
ATOM 8977  O O   . ALA D 1 17  ? -16.812 -56.582 50.685  1.00 68.76  ? 17  ALA D O   1 
ATOM 8978  C CB  . ALA D 1 17  ? -15.982 -53.656 50.143  1.00 60.09  ? 17  ALA D CB  1 
ATOM 8979  N N   . HIS D 1 18  ? -18.035 -56.022 48.863  1.00 87.64  ? 18  HIS D N   1 
ATOM 8980  C CA  . HIS D 1 18  ? -18.144 -57.401 48.401  1.00 93.97  ? 18  HIS D CA  1 
ATOM 8981  C C   . HIS D 1 18  ? -16.789 -58.013 48.070  1.00 85.24  ? 18  HIS D C   1 
ATOM 8982  O O   . HIS D 1 18  ? -16.673 -59.242 48.017  1.00 84.45  ? 18  HIS D O   1 
ATOM 8983  C CB  . HIS D 1 18  ? -19.075 -57.475 47.189  1.00 96.26  ? 18  HIS D CB  1 
ATOM 8984  C CG  . HIS D 1 18  ? -20.510 -57.208 47.517  1.00 108.37 ? 18  HIS D CG  1 
ATOM 8985  N ND1 . HIS D 1 18  ? -21.158 -56.050 47.144  1.00 117.90 ? 18  HIS D ND1 1 
ATOM 8986  C CD2 . HIS D 1 18  ? -21.417 -57.942 48.205  1.00 95.87  ? 18  HIS D CD2 1 
ATOM 8987  C CE1 . HIS D 1 18  ? -22.406 -56.088 47.575  1.00 110.73 ? 18  HIS D CE1 1 
ATOM 8988  N NE2 . HIS D 1 18  ? -22.589 -57.227 48.223  1.00 103.46 ? 18  HIS D NE2 1 
ATOM 8989  N N   . GLY D 1 19  ? -15.763 -57.186 47.852  1.00 73.88  ? 19  GLY D N   1 
ATOM 8990  C CA  . GLY D 1 19  ? -14.417 -57.708 47.703  1.00 75.08  ? 19  GLY D CA  1 
ATOM 8991  C C   . GLY D 1 19  ? -13.852 -58.311 48.974  1.00 74.22  ? 19  GLY D C   1 
ATOM 8992  O O   . GLY D 1 19  ? -12.906 -59.102 48.904  1.00 59.22  ? 19  GLY D O   1 
ATOM 8993  N N   . HIS D 1 20  ? -14.408 -57.951 50.133  1.00 68.06  ? 20  HIS D N   1 
ATOM 8994  C CA  . HIS D 1 20  ? -13.996 -58.529 51.403  1.00 64.81  ? 20  HIS D CA  1 
ATOM 8995  C C   . HIS D 1 20  ? -15.040 -59.452 52.009  1.00 67.52  ? 20  HIS D C   1 
ATOM 8996  O O   . HIS D 1 20  ? -14.715 -60.195 52.943  1.00 71.02  ? 20  HIS D O   1 
ATOM 8997  C CB  . HIS D 1 20  ? -13.651 -57.422 52.411  1.00 62.12  ? 20  HIS D CB  1 
ATOM 8998  C CG  . HIS D 1 20  ? -12.453 -56.611 52.032  1.00 63.46  ? 20  HIS D CG  1 
ATOM 8999  N ND1 . HIS D 1 20  ? -12.460 -55.717 50.981  1.00 60.37  ? 20  HIS D ND1 1 
ATOM 9000  C CD2 . HIS D 1 20  ? -11.205 -56.563 52.557  1.00 58.55  ? 20  HIS D CD2 1 
ATOM 9001  C CE1 . HIS D 1 20  ? -11.270 -55.150 50.880  1.00 66.26  ? 20  HIS D CE1 1 
ATOM 9002  N NE2 . HIS D 1 20  ? -10.491 -55.646 51.825  1.00 65.33  ? 20  HIS D NE2 1 
ATOM 9003  N N   . ILE D 1 21  ? -16.278 -59.430 51.510  1.00 68.75  ? 21  ILE D N   1 
ATOM 9004  C CA  . ILE D 1 21  ? -17.298 -60.329 52.031  1.00 61.38  ? 21  ILE D CA  1 
ATOM 9005  C C   . ILE D 1 21  ? -17.041 -61.757 51.569  1.00 62.75  ? 21  ILE D C   1 
ATOM 9006  O O   . ILE D 1 21  ? -17.230 -62.715 52.326  1.00 64.22  ? 21  ILE D O   1 
ATOM 9007  C CB  . ILE D 1 21  ? -18.699 -59.841 51.616  1.00 59.06  ? 21  ILE D CB  1 
ATOM 9008  C CG1 . ILE D 1 21  ? -18.998 -58.484 52.250  1.00 51.81  ? 21  ILE D CG1 1 
ATOM 9009  C CG2 . ILE D 1 21  ? -19.757 -60.849 52.023  1.00 62.25  ? 21  ILE D CG2 1 
ATOM 9010  C CD1 . ILE D 1 21  ? -19.211 -58.553 53.746  1.00 68.48  ? 21  ILE D CD1 1 
ATOM 9011  N N   . SER D 1 22  ? -16.597 -61.927 50.318  1.00 54.11  ? 22  SER D N   1 
ATOM 9012  C CA  . SER D 1 22  ? -16.354 -63.276 49.809  1.00 63.71  ? 22  SER D CA  1 
ATOM 9013  C C   . SER D 1 22  ? -15.211 -63.977 50.533  1.00 53.88  ? 22  SER D C   1 
ATOM 9014  O O   . SER D 1 22  ? -15.393 -65.136 50.945  1.00 49.17  ? 22  SER D O   1 
ATOM 9015  C CB  . SER D 1 22  ? -16.126 -63.231 48.294  1.00 75.07  ? 22  SER D CB  1 
ATOM 9016  O OG  . SER D 1 22  ? -17.258 -62.710 47.626  1.00 90.60  ? 22  SER D OG  1 
ATOM 9017  N N   . PRO D 1 23  ? -14.027 -63.373 50.714  1.00 55.10  ? 23  PRO D N   1 
ATOM 9018  C CA  . PRO D 1 23  ? -12.971 -64.095 51.445  1.00 53.44  ? 23  PRO D CA  1 
ATOM 9019  C C   . PRO D 1 23  ? -13.362 -64.431 52.875  1.00 51.62  ? 23  PRO D C   1 
ATOM 9020  O O   . PRO D 1 23  ? -13.074 -65.539 53.346  1.00 49.23  ? 23  PRO D O   1 
ATOM 9021  C CB  . PRO D 1 23  ? -11.781 -63.128 51.389  1.00 51.62  ? 23  PRO D CB  1 
ATOM 9022  C CG  . PRO D 1 23  ? -12.052 -62.256 50.217  1.00 55.33  ? 23  PRO D CG  1 
ATOM 9023  C CD  . PRO D 1 23  ? -13.536 -62.080 50.205  1.00 58.70  ? 23  PRO D CD  1 
ATOM 9024  N N   . PHE D 1 24  ? -14.024 -63.507 53.578  1.00 51.42  ? 24  PHE D N   1 
ATOM 9025  C CA  . PHE D 1 24  ? -14.483 -63.797 54.931  1.00 53.29  ? 24  PHE D CA  1 
ATOM 9026  C C   . PHE D 1 24  ? -15.500 -64.931 54.941  1.00 53.93  ? 24  PHE D C   1 
ATOM 9027  O O   . PHE D 1 24  ? -15.454 -65.804 55.815  1.00 52.11  ? 24  PHE D O   1 
ATOM 9028  C CB  . PHE D 1 24  ? -15.077 -62.538 55.564  1.00 55.38  ? 24  PHE D CB  1 
ATOM 9029  C CG  . PHE D 1 24  ? -14.067 -61.686 56.283  1.00 50.74  ? 24  PHE D CG  1 
ATOM 9030  C CD1 . PHE D 1 24  ? -13.207 -60.861 55.580  1.00 39.67  ? 24  PHE D CD1 1 
ATOM 9031  C CD2 . PHE D 1 24  ? -13.987 -61.711 57.665  1.00 46.21  ? 24  PHE D CD2 1 
ATOM 9032  C CE1 . PHE D 1 24  ? -12.281 -60.077 56.242  1.00 39.31  ? 24  PHE D CE1 1 
ATOM 9033  C CE2 . PHE D 1 24  ? -13.062 -60.931 58.334  1.00 39.76  ? 24  PHE D CE2 1 
ATOM 9034  C CZ  . PHE D 1 24  ? -12.210 -60.111 57.620  1.00 37.55  ? 24  PHE D CZ  1 
ATOM 9035  N N   . PHE D 1 25  ? -16.417 -64.950 53.969  1.00 58.92  ? 25  PHE D N   1 
ATOM 9036  C CA  . PHE D 1 25  ? -17.425 -66.005 53.926  1.00 57.57  ? 25  PHE D CA  1 
ATOM 9037  C C   . PHE D 1 25  ? -16.803 -67.358 53.611  1.00 58.33  ? 25  PHE D C   1 
ATOM 9038  O O   . PHE D 1 25  ? -17.205 -68.382 54.178  1.00 58.04  ? 25  PHE D O   1 
ATOM 9039  C CB  . PHE D 1 25  ? -18.504 -65.659 52.902  1.00 52.50  ? 25  PHE D CB  1 
ATOM 9040  C CG  . PHE D 1 25  ? -19.501 -66.759 52.678  1.00 53.85  ? 25  PHE D CG  1 
ATOM 9041  C CD1 . PHE D 1 25  ? -20.269 -67.239 53.727  1.00 59.30  ? 25  PHE D CD1 1 
ATOM 9042  C CD2 . PHE D 1 25  ? -19.678 -67.310 51.419  1.00 61.34  ? 25  PHE D CD2 1 
ATOM 9043  C CE1 . PHE D 1 25  ? -21.188 -68.251 53.527  1.00 66.00  ? 25  PHE D CE1 1 
ATOM 9044  C CE2 . PHE D 1 25  ? -20.603 -68.319 51.211  1.00 66.72  ? 25  PHE D CE2 1 
ATOM 9045  C CZ  . PHE D 1 25  ? -21.358 -68.789 52.268  1.00 72.71  ? 25  PHE D CZ  1 
ATOM 9046  N N   . GLU D 1 26  ? -15.821 -67.386 52.710  1.00 58.52  ? 26  GLU D N   1 
ATOM 9047  C CA  . GLU D 1 26  ? -15.153 -68.644 52.397  1.00 63.71  ? 26  GLU D CA  1 
ATOM 9048  C C   . GLU D 1 26  ? -14.326 -69.136 53.578  1.00 59.86  ? 26  GLU D C   1 
ATOM 9049  O O   . GLU D 1 26  ? -14.299 -70.339 53.863  1.00 57.85  ? 26  GLU D O   1 
ATOM 9050  C CB  . GLU D 1 26  ? -14.283 -68.483 51.149  1.00 55.54  ? 26  GLU D CB  1 
ATOM 9051  C CG  . GLU D 1 26  ? -15.082 -68.302 49.864  1.00 63.09  ? 26  GLU D CG  1 
ATOM 9052  C CD  . GLU D 1 26  ? -15.933 -69.513 49.525  1.00 66.04  ? 26  GLU D CD  1 
ATOM 9053  O OE1 . GLU D 1 26  ? -15.569 -70.636 49.940  1.00 71.15  ? 26  GLU D OE1 1 
ATOM 9054  O OE2 . GLU D 1 26  ? -16.968 -69.347 48.846  1.00 71.03  ? 26  GLU D OE2 1 
ATOM 9055  N N   . LEU D 1 27  ? -13.656 -68.221 54.284  1.00 56.49  ? 27  LEU D N   1 
ATOM 9056  C CA  . LEU D 1 27  ? -12.968 -68.606 55.512  1.00 53.49  ? 27  LEU D CA  1 
ATOM 9057  C C   . LEU D 1 27  ? -13.951 -69.132 56.544  1.00 52.78  ? 27  LEU D C   1 
ATOM 9058  O O   . LEU D 1 27  ? -13.636 -70.062 57.294  1.00 60.09  ? 27  LEU D O   1 
ATOM 9059  C CB  . LEU D 1 27  ? -12.184 -67.423 56.074  1.00 56.44  ? 27  LEU D CB  1 
ATOM 9060  C CG  . LEU D 1 27  ? -11.378 -67.705 57.344  1.00 56.40  ? 27  LEU D CG  1 
ATOM 9061  C CD1 . LEU D 1 27  ? -10.363 -68.814 57.106  1.00 63.57  ? 27  LEU D CD1 1 
ATOM 9062  C CD2 . LEU D 1 27  ? -10.691 -66.441 57.826  1.00 44.24  ? 27  LEU D CD2 1 
ATOM 9063  N N   . ALA D 1 28  ? -15.150 -68.549 56.602  1.00 49.07  ? 28  ALA D N   1 
ATOM 9064  C CA  . ALA D 1 28  ? -16.181 -69.051 57.502  1.00 49.07  ? 28  ALA D CA  1 
ATOM 9065  C C   . ALA D 1 28  ? -16.562 -70.483 57.154  1.00 56.73  ? 28  ALA D C   1 
ATOM 9066  O O   . ALA D 1 28  ? -16.644 -71.351 58.029  1.00 59.62  ? 28  ALA D O   1 
ATOM 9067  C CB  . ALA D 1 28  ? -17.409 -68.140 57.453  1.00 51.20  ? 28  ALA D CB  1 
ATOM 9068  N N   . LYS D 1 29  ? -16.802 -70.745 55.868  1.00 58.23  ? 29  LYS D N   1 
ATOM 9069  C CA  . LYS D 1 29  ? -17.130 -72.102 55.438  1.00 62.58  ? 29  LYS D CA  1 
ATOM 9070  C C   . LYS D 1 29  ? -15.993 -73.072 55.737  1.00 59.82  ? 29  LYS D C   1 
ATOM 9071  O O   . LYS D 1 29  ? -16.232 -74.240 56.061  1.00 60.09  ? 29  LYS D O   1 
ATOM 9072  C CB  . LYS D 1 29  ? -17.454 -72.119 53.945  1.00 56.40  ? 29  LYS D CB  1 
ATOM 9073  C CG  . LYS D 1 29  ? -18.605 -71.219 53.549  1.00 57.55  ? 29  LYS D CG  1 
ATOM 9074  C CD  . LYS D 1 29  ? -18.714 -71.119 52.039  1.00 62.56  ? 29  LYS D CD  1 
ATOM 9075  C CE  . LYS D 1 29  ? -19.074 -72.459 51.417  1.00 67.04  ? 29  LYS D CE  1 
ATOM 9076  N NZ  . LYS D 1 29  ? -19.269 -72.344 49.947  1.00 75.24  ? 29  LYS D NZ  1 
ATOM 9077  N N   . GLN D 1 30  ? -14.746 -72.606 55.631  1.00 56.74  ? 30  GLN D N   1 
ATOM 9078  C CA  . GLN D 1 30  ? -13.613 -73.492 55.881  1.00 57.25  ? 30  GLN D CA  1 
ATOM 9079  C C   . GLN D 1 30  ? -13.441 -73.778 57.369  1.00 59.70  ? 30  GLN D C   1 
ATOM 9080  O O   . GLN D 1 30  ? -13.089 -74.899 57.755  1.00 52.43  ? 30  GLN D O   1 
ATOM 9081  C CB  . GLN D 1 30  ? -12.336 -72.892 55.298  1.00 53.36  ? 30  GLN D CB  1 
ATOM 9082  C CG  . GLN D 1 30  ? -12.312 -72.872 53.782  1.00 60.57  ? 30  GLN D CG  1 
ATOM 9083  C CD  . GLN D 1 30  ? -12.495 -74.253 53.180  1.00 66.20  ? 30  GLN D CD  1 
ATOM 9084  O OE1 . GLN D 1 30  ? -11.901 -75.229 53.642  1.00 73.39  ? 30  GLN D OE1 1 
ATOM 9085  N NE2 . GLN D 1 30  ? -13.329 -74.342 52.149  1.00 64.32  ? 30  GLN D NE2 1 
ATOM 9086  N N   . LEU D 1 31  ? -13.677 -72.783 58.221  1.00 56.09  ? 31  LEU D N   1 
ATOM 9087  C CA  . LEU D 1 31  ? -13.531 -73.007 59.651  1.00 58.74  ? 31  LEU D CA  1 
ATOM 9088  C C   . LEU D 1 31  ? -14.750 -73.678 60.264  1.00 61.10  ? 31  LEU D C   1 
ATOM 9089  O O   . LEU D 1 31  ? -14.662 -74.185 61.387  1.00 51.85  ? 31  LEU D O   1 
ATOM 9090  C CB  . LEU D 1 31  ? -13.254 -71.687 60.373  1.00 48.77  ? 31  LEU D CB  1 
ATOM 9091  C CG  . LEU D 1 31  ? -12.082 -70.821 59.902  1.00 56.21  ? 31  LEU D CG  1 
ATOM 9092  C CD1 . LEU D 1 31  ? -11.831 -69.686 60.875  1.00 58.35  ? 31  LEU D CD1 1 
ATOM 9093  C CD2 . LEU D 1 31  ? -10.826 -71.642 59.704  1.00 58.61  ? 31  LEU D CD2 1 
ATOM 9094  N N   . ALA D 1 32  ? -15.884 -73.695 59.558  1.00 64.43  ? 32  ALA D N   1 
ATOM 9095  C CA  . ALA D 1 32  ? -17.077 -74.361 60.069  1.00 53.62  ? 32  ALA D CA  1 
ATOM 9096  C C   . ALA D 1 32  ? -17.067 -75.862 59.817  1.00 57.07  ? 32  ALA D C   1 
ATOM 9097  O O   . ALA D 1 32  ? -17.764 -76.599 60.525  1.00 61.05  ? 32  ALA D O   1 
ATOM 9098  C CB  . ALA D 1 32  ? -18.330 -73.743 59.446  1.00 58.46  ? 32  ALA D CB  1 
ATOM 9099  N N   . LYS D 1 33  ? -16.300 -76.332 58.838  1.00 62.90  ? 33  LYS D N   1 
ATOM 9100  C CA  . LYS D 1 33  ? -16.235 -77.753 58.530  1.00 64.23  ? 33  LYS D CA  1 
ATOM 9101  C C   . LYS D 1 33  ? -15.162 -78.489 59.317  1.00 69.37  ? 33  LYS D C   1 
ATOM 9102  O O   . LYS D 1 33  ? -15.082 -79.719 59.223  1.00 80.61  ? 33  LYS D O   1 
ATOM 9103  C CB  . LYS D 1 33  ? -16.001 -77.953 57.031  1.00 65.29  ? 33  LYS D CB  1 
ATOM 9104  C CG  . LYS D 1 33  ? -14.802 -77.200 56.498  1.00 65.50  ? 33  LYS D CG  1 
ATOM 9105  C CD  . LYS D 1 33  ? -14.768 -77.204 54.983  1.00 80.52  ? 33  LYS D CD  1 
ATOM 9106  C CE  . LYS D 1 33  ? -14.477 -78.587 54.437  1.00 91.27  ? 33  LYS D CE  1 
ATOM 9107  N NZ  . LYS D 1 33  ? -14.329 -78.560 52.955  1.00 90.04  ? 33  LYS D NZ  1 
ATOM 9108  N N   . ARG D 1 34  ? -14.360 -77.705 60.050  1.00 69.48  ? 34  ARG D N   1 
ATOM 9109  C CA  . ARG D 1 34  ? -13.263 -78.259 60.880  1.00 68.93  ? 34  ARG D CA  1 
ATOM 9110  C C   . ARG D 1 34  ? -13.424 -77.758 62.311  1.00 73.49  ? 34  ARG D C   1 
ATOM 9111  O O   . ARG D 1 34  ? -13.674 -76.563 62.487  1.00 78.08  ? 34  ARG D O   1 
ATOM 9112  C CB  . ARG D 1 34  ? -11.893 -77.852 60.343  1.00 60.11  ? 34  ARG D CB  1 
ATOM 9113  C CG  . ARG D 1 34  ? -11.723 -76.380 60.012  1.00 65.14  ? 34  ARG D CG  1 
ATOM 9114  C CD  . ARG D 1 34  ? -10.420 -76.249 59.256  1.00 69.08  ? 34  ARG D CD  1 
ATOM 9115  N NE  . ARG D 1 34  ? -10.239 -77.362 58.342  1.00 65.19  ? 34  ARG D NE  1 
ATOM 9116  C CZ  . ARG D 1 34  ? -10.420 -77.304 57.031  1.00 73.50  ? 34  ARG D CZ  1 
ATOM 9117  N NH1 . ARG D 1 34  ? -10.773 -76.170 56.455  1.00 75.05  ? 34  ARG D NH1 1 
ATOM 9118  N NH2 . ARG D 1 34  ? -10.235 -78.384 56.298  1.00 75.50  ? 34  ARG D NH2 1 
ATOM 9119  N N   . ASN D 1 35  ? -13.407 -78.667 63.281  1.00 70.09  ? 35  ASN D N   1 
ATOM 9120  C CA  . ASN D 1 35  ? -13.526 -78.312 64.722  1.00 75.77  ? 35  ASN D CA  1 
ATOM 9121  C C   . ASN D 1 35  ? -14.942 -77.823 64.983  1.00 72.94  ? 35  ASN D C   1 
ATOM 9122  O O   . ASN D 1 35  ? -15.187 -77.330 66.092  1.00 78.23  ? 35  ASN D O   1 
ATOM 9123  C CB  . ASN D 1 35  ? -12.393 -77.427 65.240  1.00 76.31  ? 35  ASN D CB  1 
ATOM 9124  C CG  . ASN D 1 35  ? -11.309 -78.227 65.934  1.00 67.58  ? 35  ASN D CG  1 
ATOM 9125  O OD1 . ASN D 1 35  ? -11.246 -79.447 65.793  1.00 71.44  ? 35  ASN D OD1 1 
ATOM 9126  N ND2 . ASN D 1 35  ? -10.453 -77.553 66.683  1.00 69.18  ? 35  ASN D ND2 1 
ATOM 9127  N N   . CYS D 1 36  ? -15.812 -77.914 63.980  1.00 71.12  ? 36  CYS D N   1 
ATOM 9128  C CA  . CYS D 1 36  ? -17.239 -77.583 64.191  1.00 81.62  ? 36  CYS D CA  1 
ATOM 9129  C C   . CYS D 1 36  ? -17.293 -76.224 64.868  1.00 78.84  ? 36  CYS D C   1 
ATOM 9130  O O   . CYS D 1 36  ? -18.101 -76.055 65.796  1.00 87.92  ? 36  CYS D O   1 
ATOM 9131  C CB  . CYS D 1 36  ? -17.927 -78.656 65.024  1.00 81.30  ? 36  CYS D CB  1 
ATOM 9132  S SG  . CYS D 1 36  ? -17.847 -80.300 64.271  1.00 80.08  ? 36  CYS D SG  1 
ATOM 9133  N N   . ASN D 1 37  ? -16.374 -75.343 64.490  1.00 63.56  ? 37  ASN D N   1 
ATOM 9134  C CA  . ASN D 1 37  ? -16.321 -73.998 65.099  1.00 57.98  ? 37  ASN D CA  1 
ATOM 9135  C C   . ASN D 1 37  ? -17.686 -73.347 64.934  1.00 52.89  ? 37  ASN D C   1 
ATOM 9136  O O   . ASN D 1 37  ? -18.163 -73.281 63.796  1.00 65.49  ? 37  ASN D O   1 
ATOM 9137  C CB  . ASN D 1 37  ? -15.187 -73.158 64.507  1.00 61.84  ? 37  ASN D CB  1 
ATOM 9138  C CG  . ASN D 1 37  ? -13.813 -73.746 64.732  1.00 64.68  ? 37  ASN D CG  1 
ATOM 9139  O OD1 . ASN D 1 37  ? -13.606 -74.502 65.676  1.00 77.23  ? 37  ASN D OD1 1 
ATOM 9140  N ND2 . ASN D 1 37  ? -12.868 -73.392 63.881  1.00 61.21  ? 37  ASN D ND2 1 
ATOM 9141  N N   . VAL D 1 38  ? -18.314 -72.948 66.045  1.00 52.03  ? 38  VAL D N   1 
ATOM 9142  C CA  . VAL D 1 38  ? -19.607 -72.205 65.960  1.00 56.02  ? 38  VAL D CA  1 
ATOM 9143  C C   . VAL D 1 38  ? -19.284 -70.907 65.226  1.00 53.18  ? 38  VAL D C   1 
ATOM 9144  O O   . VAL D 1 38  ? -18.382 -70.183 65.689  1.00 47.61  ? 38  VAL D O   1 
ATOM 9145  C CB  . VAL D 1 38  ? -20.192 -71.933 67.358  1.00 53.21  ? 38  VAL D CB  1 
ATOM 9146  C CG1 . VAL D 1 38  ? -21.521 -71.195 67.285  1.00 44.21  ? 38  VAL D CG1 1 
ATOM 9147  C CG2 . VAL D 1 38  ? -20.332 -73.213 68.167  1.00 67.01  ? 38  VAL D CG2 1 
ATOM 9148  N N   . PHE D 1 39  ? -20.008 -70.586 64.161  1.00 69.12  ? 39  PHE D N   1 
ATOM 9149  C CA  . PHE D 1 39  ? -19.572 -69.422 63.364  1.00 55.00  ? 39  PHE D CA  1 
ATOM 9150  C C   . PHE D 1 39  ? -20.603 -68.311 63.320  1.00 56.16  ? 39  PHE D C   1 
ATOM 9151  O O   . PHE D 1 39  ? -21.731 -68.590 62.971  1.00 54.55  ? 39  PHE D O   1 
ATOM 9152  C CB  . PHE D 1 39  ? -19.145 -69.890 61.982  1.00 58.79  ? 39  PHE D CB  1 
ATOM 9153  C CG  . PHE D 1 39  ? -17.953 -70.781 62.105  1.00 58.89  ? 39  PHE D CG  1 
ATOM 9154  C CD1 . PHE D 1 39  ? -16.691 -70.235 62.207  1.00 57.29  ? 39  PHE D CD1 1 
ATOM 9155  C CD2 . PHE D 1 39  ? -18.093 -72.147 61.986  1.00 68.85  ? 39  PHE D CD2 1 
ATOM 9156  C CE1 . PHE D 1 39  ? -15.583 -71.057 62.257  1.00 66.32  ? 39  PHE D CE1 1 
ATOM 9157  C CE2 . PHE D 1 39  ? -16.984 -72.965 62.055  1.00 66.82  ? 39  PHE D CE2 1 
ATOM 9158  C CZ  . PHE D 1 39  ? -15.734 -72.419 62.186  1.00 63.94  ? 39  PHE D CZ  1 
ATOM 9159  N N   . LEU D 1 40  ? -20.175 -67.095 63.651  1.00 47.99  ? 40  LEU D N   1 
ATOM 9160  C CA  . LEU D 1 40  ? -21.084 -65.921 63.624  1.00 41.27  ? 40  LEU D CA  1 
ATOM 9161  C C   . LEU D 1 40  ? -20.463 -64.891 62.676  1.00 46.76  ? 40  LEU D C   1 
ATOM 9162  O O   . LEU D 1 40  ? -19.254 -64.650 62.799  1.00 50.26  ? 40  LEU D O   1 
ATOM 9163  C CB  . LEU D 1 40  ? -21.178 -65.363 65.048  1.00 39.02  ? 40  LEU D CB  1 
ATOM 9164  C CG  . LEU D 1 40  ? -21.365 -66.407 66.148  1.00 53.99  ? 40  LEU D CG  1 
ATOM 9165  C CD1 . LEU D 1 40  ? -20.781 -65.927 67.469  1.00 62.16  ? 40  LEU D CD1 1 
ATOM 9166  C CD2 . LEU D 1 40  ? -22.831 -66.782 66.306  1.00 62.23  ? 40  LEU D CD2 1 
ATOM 9167  N N   . CYS D 1 41  ? -21.141 -64.460 61.604  1.00 53.97  ? 41  CYS D N   1 
ATOM 9168  C CA  . CYS D 1 41  ? -20.563 -63.514 60.588  1.00 40.41  ? 41  CYS D CA  1 
ATOM 9169  C C   . CYS D 1 41  ? -21.392 -62.233 60.583  1.00 47.12  ? 41  CYS D C   1 
ATOM 9170  O O   . CYS D 1 41  ? -22.591 -62.347 60.379  1.00 48.73  ? 41  CYS D O   1 
ATOM 9171  C CB  . CYS D 1 41  ? -20.552 -64.118 59.193  1.00 39.10  ? 41  CYS D CB  1 
ATOM 9172  S SG  . CYS D 1 41  ? -19.604 -63.190 57.961  1.00 65.31  ? 41  CYS D SG  1 
ATOM 9173  N N   . SER D 1 42  ? -20.801 -61.113 61.012  1.00 42.14  ? 42  SER D N   1 
ATOM 9174  C CA  . SER D 1 42  ? -21.574 -59.851 61.174  1.00 43.96  ? 42  SER D CA  1 
ATOM 9175  C C   . SER D 1 42  ? -21.569 -59.045 59.878  1.00 46.87  ? 42  SER D C   1 
ATOM 9176  O O   . SER D 1 42  ? -20.527 -58.437 59.560  1.00 53.71  ? 42  SER D O   1 
ATOM 9177  C CB  . SER D 1 42  ? -21.053 -59.041 62.330  1.00 43.93  ? 42  SER D CB  1 
ATOM 9178  O OG  . SER D 1 42  ? -21.884 -57.916 62.571  1.00 51.61  ? 42  SER D OG  1 
ATOM 9179  N N   . THR D 1 43  ? -22.700 -59.039 59.172  1.00 61.70  ? 43  THR D N   1 
ATOM 9180  C CA  . THR D 1 43  ? -22.803 -58.302 57.889  1.00 60.20  ? 43  THR D CA  1 
ATOM 9181  C C   . THR D 1 43  ? -24.139 -57.560 57.857  1.00 70.90  ? 43  THR D C   1 
ATOM 9182  O O   . THR D 1 43  ? -25.085 -58.034 58.514  1.00 77.96  ? 43  THR D O   1 
ATOM 9183  C CB  . THR D 1 43  ? -22.715 -59.287 56.717  1.00 69.66  ? 43  THR D CB  1 
ATOM 9184  O OG1 . THR D 1 43  ? -23.458 -60.442 57.107  1.00 64.69  ? 43  THR D OG1 1 
ATOM 9185  C CG2 . THR D 1 43  ? -21.298 -59.706 56.398  1.00 57.46  ? 43  THR D CG2 1 
ATOM 9186  N N   . PRO D 1 44  ? -24.273 -56.359 57.228  1.00 74.71  ? 44  PRO D N   1 
ATOM 9187  C CA  . PRO D 1 44  ? -25.582 -55.709 57.047  1.00 66.43  ? 44  PRO D CA  1 
ATOM 9188  C C   . PRO D 1 44  ? -26.482 -56.644 56.231  1.00 62.58  ? 44  PRO D C   1 
ATOM 9189  O O   . PRO D 1 44  ? -25.946 -57.357 55.421  1.00 56.61  ? 44  PRO D O   1 
ATOM 9190  C CB  . PRO D 1 44  ? -25.277 -54.398 56.326  1.00 62.46  ? 44  PRO D CB  1 
ATOM 9191  C CG  . PRO D 1 44  ? -23.875 -54.090 56.744  1.00 75.35  ? 44  PRO D CG  1 
ATOM 9192  C CD  . PRO D 1 44  ? -23.211 -55.451 56.749  1.00 83.65  ? 44  PRO D CD  1 
ATOM 9193  N N   . ILE D 1 45  ? -27.804 -56.610 56.423  1.00 64.74  ? 45  ILE D N   1 
ATOM 9194  C CA  . ILE D 1 45  ? -28.736 -57.604 55.812  1.00 67.36  ? 45  ILE D CA  1 
ATOM 9195  C C   . ILE D 1 45  ? -28.562 -57.601 54.286  1.00 61.80  ? 45  ILE D C   1 
ATOM 9196  O O   . ILE D 1 45  ? -28.558 -58.698 53.699  1.00 55.49  ? 45  ILE D O   1 
ATOM 9197  C CB  . ILE D 1 45  ? -30.191 -57.337 56.257  1.00 77.94  ? 45  ILE D CB  1 
ATOM 9198  C CG1 . ILE D 1 45  ? -31.183 -58.315 55.620  1.00 83.69  ? 45  ILE D CG1 1 
ATOM 9199  C CG2 . ILE D 1 45  ? -30.588 -55.886 56.018  1.00 73.53  ? 45  ILE D CG2 1 
ATOM 9200  C CD1 . ILE D 1 45  ? -31.005 -59.747 56.068  1.00 51.81  ? 45  ILE D CD1 1 
ATOM 9201  N N   . ASN D 1 46  ? -28.380 -56.426 53.677  1.00 55.48  ? 46  ASN D N   1 
ATOM 9202  C CA  . ASN D 1 46  ? -28.171 -56.344 52.207  1.00 62.72  ? 46  ASN D CA  1 
ATOM 9203  C C   . ASN D 1 46  ? -26.880 -57.083 51.822  1.00 54.62  ? 46  ASN D C   1 
ATOM 9204  O O   . ASN D 1 46  ? -26.897 -57.808 50.813  1.00 53.56  ? 46  ASN D O   1 
ATOM 9205  C CB  . ASN D 1 46  ? -28.129 -54.892 51.729  1.00 64.55  ? 46  ASN D CB  1 
ATOM 9206  C CG  . ASN D 1 46  ? -28.121 -54.757 50.221  1.00 68.04  ? 46  ASN D CG  1 
ATOM 9207  O OD1 . ASN D 1 46  ? -28.677 -55.595 49.514  1.00 77.48  ? 46  ASN D OD1 1 
ATOM 9208  N ND2 . ASN D 1 46  ? -27.504 -53.700 49.720  1.00 58.63  ? 46  ASN D ND2 1 
ATOM 9209  N N   . LEU D 1 47  ? -25.802 -56.892 52.587  1.00 57.84  ? 47  LEU D N   1 
ATOM 9210  C CA  . LEU D 1 47  ? -24.517 -57.591 52.300  1.00 59.67  ? 47  LEU D CA  1 
ATOM 9211  C C   . LEU D 1 47  ? -24.643 -59.103 52.527  1.00 53.34  ? 47  LEU D C   1 
ATOM 9212  O O   . LEU D 1 47  ? -24.067 -59.861 51.734  1.00 54.37  ? 47  LEU D O   1 
ATOM 9213  C CB  . LEU D 1 47  ? -23.387 -56.977 53.132  1.00 57.25  ? 47  LEU D CB  1 
ATOM 9214  C CG  . LEU D 1 47  ? -22.447 -56.054 52.356  1.00 46.73  ? 47  LEU D CG  1 
ATOM 9215  C CD1 . LEU D 1 47  ? -23.203 -54.885 51.747  1.00 55.93  ? 47  LEU D CD1 1 
ATOM 9216  C CD2 . LEU D 1 47  ? -21.327 -55.552 53.249  1.00 65.36  ? 47  LEU D CD2 1 
ATOM 9217  N N   . SER D 1 48  ? -25.347 -59.521 53.584  1.00 60.48  ? 48  SER D N   1 
ATOM 9218  C CA  . SER D 1 48  ? -25.464 -60.969 53.906  1.00 65.65  ? 48  SER D CA  1 
ATOM 9219  C C   . SER D 1 48  ? -26.388 -61.640 52.887  1.00 64.98  ? 48  SER D C   1 
ATOM 9220  O O   . SER D 1 48  ? -26.204 -62.841 52.622  1.00 69.06  ? 48  SER D O   1 
ATOM 9221  C CB  . SER D 1 48  ? -25.980 -61.162 55.307  1.00 71.61  ? 48  SER D CB  1 
ATOM 9222  O OG  . SER D 1 48  ? -27.306 -60.674 55.431  1.00 76.29  ? 48  SER D OG  1 
ATOM 9223  N N   . SER D 1 49  ? -27.338 -60.884 52.338  1.00 68.53  ? 49  SER D N   1 
ATOM 9224  C CA  . SER D 1 49  ? -28.325 -61.430 51.364  1.00 65.83  ? 49  SER D CA  1 
ATOM 9225  C C   . SER D 1 49  ? -27.647 -62.179 50.225  1.00 71.90  ? 49  SER D C   1 
ATOM 9226  O O   . SER D 1 49  ? -28.177 -63.214 49.817  1.00 80.94  ? 49  SER D O   1 
ATOM 9227  C CB  . SER D 1 49  ? -29.148 -60.322 50.794  1.00 58.54  ? 49  SER D CB  1 
ATOM 9228  O OG  . SER D 1 49  ? -28.442 -59.658 49.761  1.00 71.43  ? 49  SER D OG  1 
ATOM 9229  N N   . ILE D 1 50  ? -26.546 -61.643 49.705  1.00 61.89  ? 50  ILE D N   1 
ATOM 9230  C CA  . ILE D 1 50  ? -25.813 -62.263 48.559  1.00 71.22  ? 50  ILE D CA  1 
ATOM 9231  C C   . ILE D 1 50  ? -25.198 -63.595 48.969  1.00 79.15  ? 50  ILE D C   1 
ATOM 9232  O O   . ILE D 1 50  ? -25.119 -64.477 48.112  1.00 85.06  ? 50  ILE D O   1 
ATOM 9233  C CB  . ILE D 1 50  ? -24.723 -61.321 48.037  1.00 74.57  ? 50  ILE D CB  1 
ATOM 9234  C CG1 . ILE D 1 50  ? -24.289 -61.735 46.630  1.00 80.63  ? 50  ILE D CG1 1 
ATOM 9235  C CG2 . ILE D 1 50  ? -23.547 -61.250 48.994  1.00 72.24  ? 50  ILE D CG2 1 
ATOM 9236  C CD1 . ILE D 1 50  ? -25.447 -62.077 45.716  1.00 72.99  ? 50  ILE D CD1 1 
ATOM 9237  N N   . LYS D 1 51  ? -24.787 -63.725 50.221  1.00 73.87  ? 51  LYS D N   1 
ATOM 9238  C CA  . LYS D 1 51  ? -24.087 -64.947 50.666  1.00 73.92  ? 51  LYS D CA  1 
ATOM 9239  C C   . LYS D 1 51  ? -25.090 -66.028 51.037  1.00 77.51  ? 51  LYS D C   1 
ATOM 9240  O O   . LYS D 1 51  ? -24.650 -67.105 51.428  1.00 77.25  ? 51  LYS D O   1 
ATOM 9241  C CB  . LYS D 1 51  ? -23.183 -64.602 51.846  1.00 63.64  ? 51  LYS D CB  1 
ATOM 9242  C CG  . LYS D 1 51  ? -21.937 -63.835 51.438  1.00 73.46  ? 51  LYS D CG  1 
ATOM 9243  C CD  . LYS D 1 51  ? -21.320 -64.406 50.176  1.00 77.62  ? 51  LYS D CD  1 
ATOM 9244  C CE  . LYS D 1 51  ? -20.186 -63.575 49.616  1.00 69.26  ? 51  LYS D CE  1 
ATOM 9245  N NZ  . LYS D 1 51  ? -19.643 -64.176 48.378  1.00 76.12  ? 51  LYS D NZ  1 
ATOM 9246  N N   . ASP D 1 52  ? -26.385 -65.758 50.930  1.00 74.73  ? 52  ASP D N   1 
ATOM 9247  C CA  . ASP D 1 52  ? -27.349 -66.793 51.391  1.00 86.26  ? 52  ASP D CA  1 
ATOM 9248  C C   . ASP D 1 52  ? -27.558 -67.797 50.252  1.00 87.96  ? 52  ASP D C   1 
ATOM 9249  O O   . ASP D 1 52  ? -28.356 -67.524 49.336  1.00 97.96  ? 52  ASP D O   1 
ATOM 9250  C CB  . ASP D 1 52  ? -28.624 -66.179 51.974  1.00 81.89  ? 52  ASP D CB  1 
ATOM 9251  C CG  . ASP D 1 52  ? -29.407 -67.129 52.854  1.00 91.66  ? 52  ASP D CG  1 
ATOM 9252  O OD1 . ASP D 1 52  ? -29.781 -68.201 52.353  1.00 100.69 ? 52  ASP D OD1 1 
ATOM 9253  O OD2 . ASP D 1 52  ? -29.641 -66.779 54.019  1.00 90.52  ? 52  ASP D OD2 1 
ATOM 9254  N N   . LYS D 1 53  ? -26.827 -68.907 50.288  1.00 85.80  ? 53  LYS D N   1 
ATOM 9255  C CA  . LYS D 1 53  ? -26.917 -69.897 49.191  1.00 95.02  ? 53  LYS D CA  1 
ATOM 9256  C C   . LYS D 1 53  ? -26.396 -71.228 49.737  1.00 102.21 ? 53  LYS D C   1 
ATOM 9257  O O   . LYS D 1 53  ? -27.201 -72.159 49.824  1.00 103.12 ? 53  LYS D O   1 
ATOM 9258  C CB  . LYS D 1 53  ? -26.190 -69.333 47.970  1.00 100.07 ? 53  LYS D CB  1 
ATOM 9259  C CG  . LYS D 1 53  ? -24.803 -68.769 48.256  1.00 88.39  ? 53  LYS D CG  1 
ATOM 9260  C CD  . LYS D 1 53  ? -23.900 -68.736 47.048  1.00 74.19  ? 53  LYS D CD  1 
ATOM 9261  C CE  . LYS D 1 53  ? -22.468 -68.379 47.387  1.00 76.31  ? 53  LYS D CE  1 
ATOM 9262  N NZ  . LYS D 1 53  ? -22.327 -66.957 47.773  1.00 70.14  ? 53  LYS D NZ  1 
ATOM 9263  N N   . ASP D 1 54  ? -25.107 -71.326 50.099  1.00 108.49 ? 54  ASP D N   1 
ATOM 9264  C CA  . ASP D 1 54  ? -24.668 -72.578 50.770  1.00 109.09 ? 54  ASP D CA  1 
ATOM 9265  C C   . ASP D 1 54  ? -23.928 -72.195 52.054  1.00 102.62 ? 54  ASP D C   1 
ATOM 9266  O O   . ASP D 1 54  ? -22.690 -72.341 52.087  1.00 87.48  ? 54  ASP D O   1 
ATOM 9267  C CB  . ASP D 1 54  ? -23.791 -73.431 49.850  1.00 114.55 ? 54  ASP D CB  1 
ATOM 9268  C CG  . ASP D 1 54  ? -24.518 -73.961 48.627  1.00 119.72 ? 54  ASP D CG  1 
ATOM 9269  O OD1 . ASP D 1 54  ? -25.726 -73.680 48.494  1.00 114.49 ? 54  ASP D OD1 1 
ATOM 9270  O OD2 . ASP D 1 54  ? -23.869 -74.651 47.816  1.00 124.93 ? 54  ASP D OD2 1 
ATOM 9271  N N   . SER D 1 55  ? -24.659 -71.715 53.065  1.00 96.38  ? 55  SER D N   1 
ATOM 9272  C CA  . SER D 1 55  ? -24.004 -71.246 54.315  1.00 83.50  ? 55  SER D CA  1 
ATOM 9273  C C   . SER D 1 55  ? -24.686 -71.858 55.543  1.00 88.17  ? 55  SER D C   1 
ATOM 9274  O O   . SER D 1 55  ? -24.440 -71.356 56.656  1.00 85.89  ? 55  SER D O   1 
ATOM 9275  C CB  . SER D 1 55  ? -24.014 -69.741 54.387  1.00 82.56  ? 55  SER D CB  1 
ATOM 9276  O OG  . SER D 1 55  ? -25.343 -69.241 54.345  1.00 86.12  ? 55  SER D OG  1 
ATOM 9277  N N   . SER D 1 56  ? -25.503 -72.902 55.355  1.00 85.14  ? 56  SER D N   1 
ATOM 9278  C CA  . SER D 1 56  ? -26.112 -73.552 56.509  1.00 77.13  ? 56  SER D CA  1 
ATOM 9279  C C   . SER D 1 56  ? -25.101 -73.851 57.609  1.00 71.99  ? 56  SER D C   1 
ATOM 9280  O O   . SER D 1 56  ? -25.491 -73.992 58.773  1.00 71.03  ? 56  SER D O   1 
ATOM 9281  C CB  . SER D 1 56  ? -26.818 -74.835 56.070  1.00 94.82  ? 56  SER D CB  1 
ATOM 9282  O OG  . SER D 1 56  ? -27.887 -74.550 55.184  1.00 108.44 ? 56  SER D OG  1 
ATOM 9283  N N   . ALA D 1 57  ? -23.813 -73.934 57.272  1.00 73.86  ? 57  ALA D N   1 
ATOM 9284  C CA  . ALA D 1 57  ? -22.789 -74.192 58.277  1.00 70.52  ? 57  ALA D CA  1 
ATOM 9285  C C   . ALA D 1 57  ? -22.509 -72.960 59.126  1.00 75.61  ? 57  ALA D C   1 
ATOM 9286  O O   . ALA D 1 57  ? -22.359 -73.066 60.347  1.00 87.64  ? 57  ALA D O   1 
ATOM 9287  C CB  . ALA D 1 57  ? -21.504 -74.683 57.609  1.00 65.78  ? 57  ALA D CB  1 
ATOM 9288  N N   . SER D 1 58  ? -22.437 -71.788 58.502  1.00 67.96  ? 58  SER D N   1 
ATOM 9289  C CA  . SER D 1 58  ? -22.204 -70.544 59.213  1.00 57.69  ? 58  SER D CA  1 
ATOM 9290  C C   . SER D 1 58  ? -23.525 -69.934 59.671  1.00 51.46  ? 58  SER D C   1 
ATOM 9291  O O   . SER D 1 58  ? -24.603 -70.283 59.187  1.00 67.76  ? 58  SER D O   1 
ATOM 9292  C CB  . SER D 1 58  ? -21.454 -69.547 58.326  1.00 59.11  ? 58  SER D CB  1 
ATOM 9293  O OG  . SER D 1 58  ? -20.251 -70.106 57.820  1.00 62.76  ? 58  SER D OG  1 
ATOM 9294  N N   . ILE D 1 59  ? -23.424 -69.008 60.619  1.00 47.55  ? 59  ILE D N   1 
ATOM 9295  C CA  . ILE D 1 59  ? -24.568 -68.260 61.125  1.00 56.27  ? 59  ILE D CA  1 
ATOM 9296  C C   . ILE D 1 59  ? -24.334 -66.787 60.815  1.00 52.97  ? 59  ILE D C   1 
ATOM 9297  O O   . ILE D 1 59  ? -23.312 -66.218 61.216  1.00 56.42  ? 59  ILE D O   1 
ATOM 9298  C CB  . ILE D 1 59  ? -24.780 -68.482 62.631  1.00 65.66  ? 59  ILE D CB  1 
ATOM 9299  C CG1 . ILE D 1 59  ? -25.207 -69.929 62.905  1.00 67.62  ? 59  ILE D CG1 1 
ATOM 9300  C CG2 . ILE D 1 59  ? -25.809 -67.504 63.179  1.00 67.92  ? 59  ILE D CG2 1 
ATOM 9301  C CD1 . ILE D 1 59  ? -25.445 -70.234 64.369  1.00 76.96  ? 59  ILE D CD1 1 
ATOM 9302  N N   . LYS D 1 60  ? -25.263 -66.244 60.048  1.00 52.69  ? 60  LYS D N   1 
ATOM 9303  C CA  . LYS D 1 60  ? -25.111 -64.846 59.620  1.00 56.08  ? 60  LYS D CA  1 
ATOM 9304  C C   . LYS D 1 60  ? -25.874 -63.983 60.614  1.00 51.06  ? 60  LYS D C   1 
ATOM 9305  O O   . LYS D 1 60  ? -26.954 -64.379 61.034  1.00 61.49  ? 60  LYS D O   1 
ATOM 9306  C CB  . LYS D 1 60  ? -25.520 -64.751 58.149  1.00 48.90  ? 60  LYS D CB  1 
ATOM 9307  C CG  . LYS D 1 60  ? -24.830 -65.751 57.238  1.00 57.38  ? 60  LYS D CG  1 
ATOM 9308  C CD  . LYS D 1 60  ? -25.751 -66.281 56.174  1.00 66.55  ? 60  LYS D CD  1 
ATOM 9309  C CE  . LYS D 1 60  ? -26.336 -65.177 55.324  1.00 73.58  ? 60  LYS D CE  1 
ATOM 9310  N NZ  . LYS D 1 60  ? -25.275 -64.363 54.689  1.00 75.05  ? 60  LYS D NZ  1 
ATOM 9311  N N   . LEU D 1 61  ? -25.292 -62.855 60.975  1.00 51.33  ? 61  LEU D N   1 
ATOM 9312  C CA  . LEU D 1 61  ? -25.873 -61.982 62.012  1.00 63.43  ? 61  LEU D CA  1 
ATOM 9313  C C   . LEU D 1 61  ? -26.057 -60.599 61.401  1.00 64.34  ? 61  LEU D C   1 
ATOM 9314  O O   . LEU D 1 61  ? -25.146 -60.127 60.745  1.00 61.77  ? 61  LEU D O   1 
ATOM 9315  C CB  . LEU D 1 61  ? -24.877 -61.977 63.168  1.00 58.16  ? 61  LEU D CB  1 
ATOM 9316  C CG  . LEU D 1 61  ? -25.003 -60.823 64.146  1.00 56.43  ? 61  LEU D CG  1 
ATOM 9317  C CD1 . LEU D 1 61  ? -26.039 -61.136 65.210  1.00 70.93  ? 61  LEU D CD1 1 
ATOM 9318  C CD2 . LEU D 1 61  ? -23.653 -60.567 64.771  1.00 66.63  ? 61  LEU D CD2 1 
ATOM 9319  N N   . VAL D 1 62  ? -27.203 -59.985 61.615  1.00 64.59  ? 62  VAL D N   1 
ATOM 9320  C CA  . VAL D 1 62  ? -27.476 -58.700 60.928  1.00 65.23  ? 62  VAL D CA  1 
ATOM 9321  C C   . VAL D 1 62  ? -26.801 -57.541 61.646  1.00 64.22  ? 62  VAL D C   1 
ATOM 9322  O O   . VAL D 1 62  ? -26.269 -57.743 62.729  1.00 69.37  ? 62  VAL D O   1 
ATOM 9323  C CB  . VAL D 1 62  ? -28.990 -58.471 60.822  1.00 82.63  ? 62  VAL D CB  1 
ATOM 9324  C CG1 . VAL D 1 62  ? -29.668 -59.532 59.973  1.00 85.17  ? 62  VAL D CG1 1 
ATOM 9325  C CG2 . VAL D 1 62  ? -29.646 -58.381 62.189  1.00 86.71  ? 62  VAL D CG2 1 
ATOM 9326  N N   . GLU D 1 63  ? -26.896 -56.356 61.047  1.00 70.29  ? 63  GLU D N   1 
ATOM 9327  C CA  . GLU D 1 63  ? -26.249 -55.185 61.626  1.00 71.98  ? 63  GLU D CA  1 
ATOM 9328  C C   . GLU D 1 63  ? -26.828 -53.943 60.968  1.00 80.97  ? 63  GLU D C   1 
ATOM 9329  O O   . GLU D 1 63  ? -26.702 -53.768 59.754  1.00 84.81  ? 63  GLU D O   1 
ATOM 9330  C CB  . GLU D 1 63  ? -24.731 -55.230 61.446  1.00 67.38  ? 63  GLU D CB  1 
ATOM 9331  C CG  . GLU D 1 63  ? -24.025 -54.036 62.057  1.00 72.85  ? 63  GLU D CG  1 
ATOM 9332  C CD  . GLU D 1 63  ? -22.528 -54.236 62.186  1.00 84.01  ? 63  GLU D CD  1 
ATOM 9333  O OE1 . GLU D 1 63  ? -21.998 -55.191 61.581  1.00 82.40  ? 63  GLU D OE1 1 
ATOM 9334  O OE2 . GLU D 1 63  ? -21.883 -53.438 62.901  1.00 77.16  ? 63  GLU D OE2 1 
ATOM 9335  N N   . LEU D 1 64  ? -27.460 -53.090 61.770  1.00 72.90  ? 64  LEU D N   1 
ATOM 9336  C CA  . LEU D 1 64  ? -28.181 -51.925 61.279  1.00 78.91  ? 64  LEU D CA  1 
ATOM 9337  C C   . LEU D 1 64  ? -27.406 -50.655 61.603  1.00 73.14  ? 64  LEU D C   1 
ATOM 9338  O O   . LEU D 1 64  ? -26.903 -50.488 62.720  1.00 69.53  ? 64  LEU D O   1 
ATOM 9339  C CB  . LEU D 1 64  ? -29.582 -51.849 61.892  1.00 75.25  ? 64  LEU D CB  1 
ATOM 9340  C CG  . LEU D 1 64  ? -30.619 -52.897 61.471  1.00 82.41  ? 64  LEU D CG  1 
ATOM 9341  C CD1 . LEU D 1 64  ? -30.619 -53.088 59.957  1.00 79.15  ? 64  LEU D CD1 1 
ATOM 9342  C CD2 . LEU D 1 64  ? -30.435 -54.231 62.195  1.00 72.11  ? 64  LEU D CD2 1 
ATOM 9343  N N   . HIS D 1 65  ? -27.318 -49.760 60.625  1.00 78.96  ? 65  HIS D N   1 
ATOM 9344  C CA  . HIS D 1 65  ? -26.615 -48.495 60.804  1.00 69.13  ? 65  HIS D CA  1 
ATOM 9345  C C   . HIS D 1 65  ? -27.607 -47.340 60.933  1.00 60.72  ? 65  HIS D C   1 
ATOM 9346  O O   . HIS D 1 65  ? -27.398 -46.260 60.378  1.00 61.71  ? 65  HIS D O   1 
ATOM 9347  C CB  . HIS D 1 65  ? -25.654 -48.244 59.638  1.00 83.88  ? 65  HIS D CB  1 
ATOM 9348  C CG  . HIS D 1 65  ? -24.546 -49.245 59.543  1.00 85.63  ? 65  HIS D CG  1 
ATOM 9349  N ND1 . HIS D 1 65  ? -24.117 -49.989 60.620  1.00 79.67  ? 65  HIS D ND1 1 
ATOM 9350  C CD2 . HIS D 1 65  ? -23.779 -49.628 58.492  1.00 86.47  ? 65  HIS D CD2 1 
ATOM 9351  C CE1 . HIS D 1 65  ? -23.131 -50.785 60.242  1.00 87.07  ? 65  HIS D CE1 1 
ATOM 9352  N NE2 . HIS D 1 65  ? -22.908 -50.584 58.957  1.00 85.87  ? 65  HIS D NE2 1 
ATOM 9353  N N   . ARG D 1 91  ? -19.335 -40.564 54.315  1.00 79.92  ? 91  ARG D N   1 
ATOM 9354  C CA  . ARG D 1 91  ? -18.733 -41.140 55.545  1.00 86.55  ? 91  ARG D CA  1 
ATOM 9355  C C   . ARG D 1 91  ? -19.489 -42.410 55.927  1.00 86.50  ? 91  ARG D C   1 
ATOM 9356  O O   . ARG D 1 91  ? -20.630 -42.280 56.388  1.00 84.94  ? 91  ARG D O   1 
ATOM 9357  C CB  . ARG D 1 91  ? -18.810 -40.134 56.694  1.00 93.01  ? 91  ARG D CB  1 
ATOM 9358  C CG  . ARG D 1 91  ? -17.993 -38.868 56.464  1.00 93.81  ? 91  ARG D CG  1 
ATOM 9359  C CD  . ARG D 1 91  ? -16.646 -38.933 57.157  1.00 91.97  ? 91  ARG D CD  1 
ATOM 9360  N NE  . ARG D 1 91  ? -16.711 -39.724 58.376  1.00 101.50 ? 91  ARG D NE  1 
ATOM 9361  C CZ  . ARG D 1 91  ? -16.694 -39.220 59.603  1.00 99.11  ? 91  ARG D CZ  1 
ATOM 9362  N NH1 . ARG D 1 91  ? -16.607 -37.912 59.779  1.00 97.87  ? 91  ARG D NH1 1 
ATOM 9363  N NH2 . ARG D 1 91  ? -16.765 -40.024 60.648  1.00 89.91  ? 91  ARG D NH2 1 
ATOM 9364  N N   . ASN D 1 92  ? -18.877 -43.582 55.726  1.00 87.43  ? 92  ASN D N   1 
ATOM 9365  C CA  . ASN D 1 92  ? -19.533 -44.831 56.179  1.00 87.17  ? 92  ASN D CA  1 
ATOM 9366  C C   . ASN D 1 92  ? -19.882 -44.653 57.652  1.00 85.75  ? 92  ASN D C   1 
ATOM 9367  O O   . ASN D 1 92  ? -19.000 -44.273 58.433  1.00 89.24  ? 92  ASN D O   1 
ATOM 9368  C CB  . ASN D 1 92  ? -18.686 -46.077 55.924  1.00 86.39  ? 92  ASN D CB  1 
ATOM 9369  C CG  . ASN D 1 92  ? -17.352 -46.081 56.643  1.00 94.29  ? 92  ASN D CG  1 
ATOM 9370  O OD1 . ASN D 1 92  ? -16.935 -45.074 57.205  1.00 94.65  ? 92  ASN D OD1 1 
ATOM 9371  N ND2 . ASN D 1 92  ? -16.661 -47.209 56.601  1.00 91.41  ? 92  ASN D ND2 1 
ATOM 9372  N N   . ALA D 1 93  ? -21.142 -44.890 57.997  1.00 76.98  ? 93  ALA D N   1 
ATOM 9373  C CA  . ALA D 1 93  ? -21.552 -44.784 59.407  1.00 83.54  ? 93  ALA D CA  1 
ATOM 9374  C C   . ALA D 1 93  ? -20.932 -45.969 60.132  1.00 81.63  ? 93  ALA D C   1 
ATOM 9375  O O   . ALA D 1 93  ? -21.014 -46.028 61.361  1.00 78.46  ? 93  ALA D O   1 
ATOM 9376  C CB  . ALA D 1 93  ? -23.045 -44.787 59.492  1.00 79.69  ? 93  ALA D CB  1 
ATOM 9377  N N   . PHE D 1 94  ? -20.316 -46.880 59.374  1.00 77.56  ? 94  PHE D N   1 
ATOM 9378  C CA  . PHE D 1 94  ? -19.604 -48.010 60.022  1.00 81.28  ? 94  PHE D CA  1 
ATOM 9379  C C   . PHE D 1 94  ? -18.759 -47.437 61.164  1.00 81.41  ? 94  PHE D C   1 
ATOM 9380  O O   . PHE D 1 94  ? -18.634 -48.108 62.206  1.00 78.80  ? 94  PHE D O   1 
ATOM 9381  C CB  . PHE D 1 94  ? -18.751 -48.766 59.003  1.00 80.66  ? 94  PHE D CB  1 
ATOM 9382  C CG  . PHE D 1 94  ? -18.468 -50.204 59.358  1.00 82.12  ? 94  PHE D CG  1 
ATOM 9383  C CD1 . PHE D 1 94  ? -19.044 -50.787 60.475  1.00 83.99  ? 94  PHE D CD1 1 
ATOM 9384  C CD2 . PHE D 1 94  ? -17.625 -50.978 58.575  1.00 81.42  ? 94  PHE D CD2 1 
ATOM 9385  C CE1 . PHE D 1 94  ? -18.784 -52.108 60.802  1.00 81.27  ? 94  PHE D CE1 1 
ATOM 9386  C CE2 . PHE D 1 94  ? -17.366 -52.299 58.901  1.00 77.72  ? 94  PHE D CE2 1 
ATOM 9387  C CZ  . PHE D 1 94  ? -17.945 -52.862 60.015  1.00 74.19  ? 94  PHE D CZ  1 
ATOM 9388  N N   . GLU D 1 95  ? -18.219 -46.227 60.976  1.00 78.34  ? 95  GLU D N   1 
ATOM 9389  C CA  . GLU D 1 95  ? -17.339 -45.652 62.022  1.00 71.48  ? 95  GLU D CA  1 
ATOM 9390  C C   . GLU D 1 95  ? -18.203 -45.117 63.161  1.00 77.48  ? 95  GLU D C   1 
ATOM 9391  O O   . GLU D 1 95  ? -17.667 -44.394 64.012  1.00 77.25  ? 95  GLU D O   1 
ATOM 9392  C CB  . GLU D 1 95  ? -16.453 -44.563 61.422  1.00 74.58  ? 95  GLU D CB  1 
ATOM 9393  C CG  . GLU D 1 95  ? -15.317 -45.114 60.581  1.00 82.64  ? 95  GLU D CG  1 
ATOM 9394  C CD  . GLU D 1 95  ? -14.226 -45.825 61.364  1.00 88.75  ? 95  GLU D CD  1 
ATOM 9395  O OE1 . GLU D 1 95  ? -14.324 -45.874 62.604  1.00 88.08  ? 95  GLU D OE1 1 
ATOM 9396  O OE2 . GLU D 1 95  ? -13.278 -46.327 60.731  1.00 87.83  ? 95  GLU D OE2 1 
ATOM 9397  N N   . THR D 1 96  ? -19.488 -45.464 63.163  1.00 81.43  ? 96  THR D N   1 
ATOM 9398  C CA  . THR D 1 96  ? -20.394 -44.998 64.235  1.00 83.34  ? 96  THR D CA  1 
ATOM 9399  C C   . THR D 1 96  ? -21.089 -46.204 64.862  1.00 76.47  ? 96  THR D C   1 
ATOM 9400  O O   . THR D 1 96  ? -21.622 -46.067 65.966  1.00 78.25  ? 96  THR D O   1 
ATOM 9401  C CB  . THR D 1 96  ? -21.400 -43.998 63.665  1.00 82.71  ? 96  THR D CB  1 
ATOM 9402  O OG1 . THR D 1 96  ? -22.342 -44.727 62.878  1.00 79.03  ? 96  THR D OG1 1 
ATOM 9403  C CG2 . THR D 1 96  ? -20.746 -42.925 62.823  1.00 83.55  ? 96  THR D CG2 1 
ATOM 9404  N N   . ALA D 1 97  ? -21.061 -47.342 64.181  1.00 65.08  ? 97  ALA D N   1 
ATOM 9405  C CA  . ALA D 1 97  ? -21.791 -48.528 64.672  1.00 69.34  ? 97  ALA D CA  1 
ATOM 9406  C C   . ALA D 1 97  ? -20.911 -49.252 65.675  1.00 66.41  ? 97  ALA D C   1 
ATOM 9407  O O   . ALA D 1 97  ? -21.089 -50.455 65.862  1.00 59.39  ? 97  ALA D O   1 
ATOM 9408  C CB  . ALA D 1 97  ? -22.128 -49.421 63.519  1.00 74.30  ? 97  ALA D CB  1 
ATOM 9409  N N   . GLY D 1 98  ? -19.992 -48.528 66.287  1.00 73.49  ? 98  GLY D N   1 
ATOM 9410  C CA  . GLY D 1 98  ? -19.187 -49.172 67.329  1.00 68.97  ? 98  GLY D CA  1 
ATOM 9411  C C   . GLY D 1 98  ? -20.105 -49.790 68.351  1.00 65.27  ? 98  GLY D C   1 
ATOM 9412  O O   . GLY D 1 98  ? -20.174 -51.023 68.418  1.00 69.68  ? 98  GLY D O   1 
ATOM 9413  N N   . PRO D 1 99  ? -20.817 -48.980 69.156  1.00 61.68  ? 99  PRO D N   1 
ATOM 9414  C CA  . PRO D 1 99  ? -21.658 -49.550 70.223  1.00 59.03  ? 99  PRO D CA  1 
ATOM 9415  C C   . PRO D 1 99  ? -22.668 -50.569 69.729  1.00 58.49  ? 99  PRO D C   1 
ATOM 9416  O O   . PRO D 1 99  ? -23.073 -51.449 70.500  1.00 64.75  ? 99  PRO D O   1 
ATOM 9417  C CB  . PRO D 1 99  ? -22.347 -48.315 70.828  1.00 60.68  ? 99  PRO D CB  1 
ATOM 9418  C CG  . PRO D 1 99  ? -22.173 -47.227 69.814  1.00 65.54  ? 99  PRO D CG  1 
ATOM 9419  C CD  . PRO D 1 99  ? -20.877 -47.510 69.135  1.00 62.83  ? 99  PRO D CD  1 
ATOM 9420  N N   . THR D 1 100 ? -23.077 -50.501 68.462  1.00 61.57  ? 100 THR D N   1 
ATOM 9421  C CA  . THR D 1 100 ? -23.958 -51.532 67.922  1.00 60.59  ? 100 THR D CA  1 
ATOM 9422  C C   . THR D 1 100 ? -23.248 -52.880 67.877  1.00 53.94  ? 100 THR D C   1 
ATOM 9423  O O   . THR D 1 100 ? -23.795 -53.903 68.307  1.00 56.70  ? 100 THR D O   1 
ATOM 9424  C CB  . THR D 1 100 ? -24.443 -51.132 66.531  1.00 56.96  ? 100 THR D CB  1 
ATOM 9425  O OG1 . THR D 1 100 ? -24.890 -49.771 66.553  1.00 55.84  ? 100 THR D OG1 1 
ATOM 9426  C CG2 . THR D 1 100 ? -25.592 -52.028 66.098  1.00 50.94  ? 100 THR D CG2 1 
ATOM 9427  N N   . PHE D 1 101 ? -22.015 -52.895 67.370  1.00 51.30  ? 101 PHE D N   1 
ATOM 9428  C CA  . PHE D 1 101 ? -21.238 -54.128 67.378  1.00 49.17  ? 101 PHE D CA  1 
ATOM 9429  C C   . PHE D 1 101 ? -20.874 -54.543 68.797  1.00 48.63  ? 101 PHE D C   1 
ATOM 9430  O O   . PHE D 1 101 ? -20.742 -55.740 69.077  1.00 50.91  ? 101 PHE D O   1 
ATOM 9431  C CB  . PHE D 1 101 ? -19.982 -53.959 66.525  1.00 41.20  ? 101 PHE D CB  1 
ATOM 9432  C CG  . PHE D 1 101 ? -19.219 -55.233 66.312  1.00 40.72  ? 101 PHE D CG  1 
ATOM 9433  C CD1 . PHE D 1 101 ? -19.812 -56.313 65.682  1.00 41.08  ? 101 PHE D CD1 1 
ATOM 9434  C CD2 . PHE D 1 101 ? -17.904 -55.346 66.733  1.00 45.18  ? 101 PHE D CD2 1 
ATOM 9435  C CE1 . PHE D 1 101 ? -19.112 -57.486 65.482  1.00 37.60  ? 101 PHE D CE1 1 
ATOM 9436  C CE2 . PHE D 1 101 ? -17.199 -56.513 66.533  1.00 46.44  ? 101 PHE D CE2 1 
ATOM 9437  C CZ  . PHE D 1 101 ? -17.802 -57.585 65.906  1.00 33.65  ? 101 PHE D CZ  1 
ATOM 9438  N N   . SER D 1 102 ? -20.716 -53.575 69.702  1.00 47.74  ? 102 SER D N   1 
ATOM 9439  C CA  . SER D 1 102 ? -20.509 -53.908 71.107  1.00 47.71  ? 102 SER D CA  1 
ATOM 9440  C C   . SER D 1 102 ? -21.708 -54.665 71.665  1.00 53.70  ? 102 SER D C   1 
ATOM 9441  O O   . SER D 1 102 ? -21.544 -55.654 72.384  1.00 57.54  ? 102 SER D O   1 
ATOM 9442  C CB  . SER D 1 102 ? -20.248 -52.638 71.918  1.00 48.73  ? 102 SER D CB  1 
ATOM 9443  O OG  . SER D 1 102 ? -20.043 -52.943 73.285  1.00 46.31  ? 102 SER D OG  1 
ATOM 9444  N N   . GLU D 1 103 ? -22.922 -54.215 71.335  1.00 52.61  ? 103 GLU D N   1 
ATOM 9445  C CA  . GLU D 1 103 ? -24.126 -54.928 71.744  1.00 52.88  ? 103 GLU D CA  1 
ATOM 9446  C C   . GLU D 1 103 ? -24.189 -56.318 71.119  1.00 50.89  ? 103 GLU D C   1 
ATOM 9447  O O   . GLU D 1 103 ? -24.581 -57.293 71.775  1.00 55.44  ? 103 GLU D O   1 
ATOM 9448  C CB  . GLU D 1 103 ? -25.364 -54.115 71.367  1.00 55.46  ? 103 GLU D CB  1 
ATOM 9449  C CG  . GLU D 1 103 ? -26.676 -54.692 71.863  1.00 66.13  ? 103 GLU D CG  1 
ATOM 9450  C CD  . GLU D 1 103 ? -26.902 -54.445 73.343  1.00 72.94  ? 103 GLU D CD  1 
ATOM 9451  O OE1 . GLU D 1 103 ? -26.221 -53.563 73.911  1.00 65.16  ? 103 GLU D OE1 1 
ATOM 9452  O OE2 . GLU D 1 103 ? -27.759 -55.130 73.936  1.00 78.00  ? 103 GLU D OE2 1 
ATOM 9453  N N   . ILE D 1 104 ? -23.811 -56.425 69.842  1.00 51.37  ? 104 ILE D N   1 
ATOM 9454  C CA  . ILE D 1 104 ? -23.827 -57.727 69.175  1.00 53.83  ? 104 ILE D CA  1 
ATOM 9455  C C   . ILE D 1 104 ? -22.882 -58.699 69.875  1.00 51.24  ? 104 ILE D C   1 
ATOM 9456  O O   . ILE D 1 104 ? -23.232 -59.856 70.131  1.00 48.94  ? 104 ILE D O   1 
ATOM 9457  C CB  . ILE D 1 104 ? -23.486 -57.572 67.682  1.00 52.30  ? 104 ILE D CB  1 
ATOM 9458  C CG1 . ILE D 1 104 ? -24.705 -57.061 66.911  1.00 43.64  ? 104 ILE D CG1 1 
ATOM 9459  C CG2 . ILE D 1 104 ? -23.000 -58.890 67.099  1.00 61.26  ? 104 ILE D CG2 1 
ATOM 9460  C CD1 . ILE D 1 104 ? -24.544 -57.078 65.410  1.00 62.02  ? 104 ILE D CD1 1 
ATOM 9461  N N   . LEU D 1 105 ? -21.671 -58.239 70.202  1.00 50.73  ? 105 LEU D N   1 
ATOM 9462  C CA  . LEU D 1 105 ? -20.727 -59.095 70.916  1.00 51.06  ? 105 LEU D CA  1 
ATOM 9463  C C   . LEU D 1 105 ? -21.199 -59.385 72.335  1.00 47.01  ? 105 LEU D C   1 
ATOM 9464  O O   . LEU D 1 105 ? -20.939 -60.474 72.863  1.00 42.46  ? 105 LEU D O   1 
ATOM 9465  C CB  . LEU D 1 105 ? -19.340 -58.455 70.948  1.00 47.34  ? 105 LEU D CB  1 
ATOM 9466  C CG  . LEU D 1 105 ? -18.624 -58.220 69.616  1.00 51.05  ? 105 LEU D CG  1 
ATOM 9467  C CD1 . LEU D 1 105 ? -17.242 -57.638 69.870  1.00 47.93  ? 105 LEU D CD1 1 
ATOM 9468  C CD2 . LEU D 1 105 ? -18.529 -59.504 68.806  1.00 39.60  ? 105 LEU D CD2 1 
ATOM 9469  N N   . LYS D 1 106 ? -21.882 -58.429 72.964  1.00 48.97  ? 106 LYS D N   1 
ATOM 9470  C CA  . LYS D 1 106 ? -22.425 -58.647 74.300  1.00 51.20  ? 106 LYS D CA  1 
ATOM 9471  C C   . LYS D 1 106 ? -23.464 -59.758 74.293  1.00 58.46  ? 106 LYS D C   1 
ATOM 9472  O O   . LYS D 1 106 ? -23.557 -60.538 75.245  1.00 58.37  ? 106 LYS D O   1 
ATOM 9473  C CB  . LYS D 1 106 ? -23.029 -57.342 74.821  1.00 53.16  ? 106 LYS D CB  1 
ATOM 9474  C CG  . LYS D 1 106 ? -23.258 -57.288 76.313  1.00 56.17  ? 106 LYS D CG  1 
ATOM 9475  C CD  . LYS D 1 106 ? -23.802 -55.926 76.712  1.00 58.74  ? 106 LYS D CD  1 
ATOM 9476  C CE  . LYS D 1 106 ? -25.236 -55.734 76.242  1.00 64.16  ? 106 LYS D CE  1 
ATOM 9477  N NZ  . LYS D 1 106 ? -26.190 -56.627 76.960  1.00 58.25  ? 106 LYS D NZ  1 
ATOM 9478  N N   . THR D 1 107 ? -24.187 -59.878 73.176  1.00 54.51  ? 107 THR D N   1 
ATOM 9479  C CA  . THR D 1 107 ? -25.177 -60.977 73.036  1.00 47.25  ? 107 THR D CA  1 
ATOM 9480  C C   . THR D 1 107 ? -24.459 -62.247 72.565  1.00 47.89  ? 107 THR D C   1 
ATOM 9481  O O   . THR D 1 107 ? -24.610 -63.287 73.233  1.00 49.84  ? 107 THR D O   1 
ATOM 9482  C CB  . THR D 1 107 ? -26.298 -60.586 72.070  1.00 57.78  ? 107 THR D CB  1 
ATOM 9483  O OG1 . THR D 1 107 ? -26.905 -59.388 72.556  1.00 58.41  ? 107 THR D OG1 1 
ATOM 9484  C CG2 . THR D 1 107 ? -27.346 -61.667 71.914  1.00 52.75  ? 107 THR D CG2 1 
ATOM 9485  N N   . LEU D 1 108 ? -23.707 -62.160 71.461  1.00 50.88  ? 108 LEU D N   1 
ATOM 9486  C CA  . LEU D 1 108 ? -23.026 -63.355 70.893  1.00 55.80  ? 108 LEU D CA  1 
ATOM 9487  C C   . LEU D 1 108 ? -21.908 -63.828 71.827  1.00 61.60  ? 108 LEU D C   1 
ATOM 9488  O O   . LEU D 1 108 ? -21.855 -65.040 72.110  1.00 57.91  ? 108 LEU D O   1 
ATOM 9489  C CB  . LEU D 1 108 ? -22.462 -62.995 69.515  1.00 57.74  ? 108 LEU D CB  1 
ATOM 9490  C CG  . LEU D 1 108 ? -23.498 -62.612 68.460  1.00 67.56  ? 108 LEU D CG  1 
ATOM 9491  C CD1 . LEU D 1 108 ? -22.930 -62.788 67.062  1.00 70.79  ? 108 LEU D CD1 1 
ATOM 9492  C CD2 . LEU D 1 108 ? -24.768 -63.429 68.626  1.00 66.82  ? 108 LEU D CD2 1 
ATOM 9493  N N   . ASN D 1 109 ? -21.050 -62.908 72.278  1.00 54.65  ? 109 ASN D N   1 
ATOM 9494  C CA  . ASN D 1 109 ? -19.900 -63.282 73.149  1.00 58.14  ? 109 ASN D CA  1 
ATOM 9495  C C   . ASN D 1 109 ? -19.097 -64.399 72.469  1.00 55.79  ? 109 ASN D C   1 
ATOM 9496  O O   . ASN D 1 109 ? -19.074 -65.525 73.007  1.00 54.36  ? 109 ASN D O   1 
ATOM 9497  C CB  . ASN D 1 109 ? -20.360 -63.679 74.555  1.00 57.95  ? 109 ASN D CB  1 
ATOM 9498  C CG  . ASN D 1 109 ? -19.230 -63.698 75.562  1.00 62.64  ? 109 ASN D CG  1 
ATOM 9499  O OD1 . ASN D 1 109 ? -18.267 -64.444 75.411  1.00 62.29  ? 109 ASN D OD1 1 
ATOM 9500  N ND2 . ASN D 1 109 ? -19.342 -62.881 76.596  1.00 67.53  ? 109 ASN D ND2 1 
ATOM 9501  N N   . PRO D 1 110 ? -18.445 -64.143 71.313  1.00 50.08  ? 110 PRO D N   1 
ATOM 9502  C CA  . PRO D 1 110 ? -17.630 -65.156 70.634  1.00 52.92  ? 110 PRO D CA  1 
ATOM 9503  C C   . PRO D 1 110 ? -16.305 -65.404 71.368  1.00 49.36  ? 110 PRO D C   1 
ATOM 9504  O O   . PRO D 1 110 ? -15.855 -64.518 72.072  1.00 49.36  ? 110 PRO D O   1 
ATOM 9505  C CB  . PRO D 1 110 ? -17.351 -64.522 69.265  1.00 50.63  ? 110 PRO D CB  1 
ATOM 9506  C CG  . PRO D 1 110 ? -17.366 -63.038 69.550  1.00 53.77  ? 110 PRO D CG  1 
ATOM 9507  C CD  . PRO D 1 110 ? -18.443 -62.863 70.599  1.00 48.43  ? 110 PRO D CD  1 
ATOM 9508  N N   . ASP D 1 111 ? -15.716 -66.590 71.181  1.00 50.34  ? 111 ASP D N   1 
ATOM 9509  C CA  . ASP D 1 111 ? -14.422 -66.923 71.837  1.00 48.31  ? 111 ASP D CA  1 
ATOM 9510  C C   . ASP D 1 111 ? -13.290 -66.186 71.118  1.00 52.13  ? 111 ASP D C   1 
ATOM 9511  O O   . ASP D 1 111 ? -12.149 -66.237 71.619  1.00 59.92  ? 111 ASP D O   1 
ATOM 9512  C CB  . ASP D 1 111 ? -14.172 -68.433 71.836  1.00 44.45  ? 111 ASP D CB  1 
ATOM 9513  C CG  . ASP D 1 111 ? -15.313 -69.239 72.435  1.00 60.62  ? 111 ASP D CG  1 
ATOM 9514  O OD1 . ASP D 1 111 ? -16.293 -68.618 72.894  1.00 67.51  ? 111 ASP D OD1 1 
ATOM 9515  O OD2 . ASP D 1 111 ? -15.217 -70.483 72.429  1.00 59.87  ? 111 ASP D OD2 1 
ATOM 9516  N N   . LEU D 1 112 ? -13.593 -65.529 69.996  1.00 49.15  ? 112 LEU D N   1 
ATOM 9517  C CA  . LEU D 1 112 ? -12.564 -64.853 69.217  1.00 52.20  ? 112 LEU D CA  1 
ATOM 9518  C C   . LEU D 1 112 ? -13.221 -64.027 68.119  1.00 51.33  ? 112 LEU D C   1 
ATOM 9519  O O   . LEU D 1 112 ? -14.282 -64.388 67.606  1.00 37.42  ? 112 LEU D O   1 
ATOM 9520  C CB  . LEU D 1 112 ? -11.576 -65.861 68.619  1.00 53.06  ? 112 LEU D CB  1 
ATOM 9521  C CG  . LEU D 1 112 ? -10.291 -65.323 67.993  1.00 51.03  ? 112 LEU D CG  1 
ATOM 9522  C CD1 . LEU D 1 112 ? -9.143  -66.266 68.291  1.00 48.78  ? 112 LEU D CD1 1 
ATOM 9523  C CD2 . LEU D 1 112 ? -10.455 -65.144 66.492  1.00 43.86  ? 112 LEU D CD2 1 
ATOM 9524  N N   . LEU D 1 113 ? -12.574 -62.919 67.764  1.00 48.12  ? 113 LEU D N   1 
ATOM 9525  C CA  . LEU D 1 113 ? -13.052 -62.029 66.718  1.00 45.60  ? 113 LEU D CA  1 
ATOM 9526  C C   . LEU D 1 113 ? -12.026 -61.948 65.595  1.00 36.62  ? 113 LEU D C   1 
ATOM 9527  O O   . LEU D 1 113 ? -10.822 -61.832 65.849  1.00 40.18  ? 113 LEU D O   1 
ATOM 9528  C CB  . LEU D 1 113 ? -13.329 -60.626 67.269  1.00 39.57  ? 113 LEU D CB  1 
ATOM 9529  C CG  . LEU D 1 113 ? -13.674 -59.554 66.234  1.00 43.11  ? 113 LEU D CG  1 
ATOM 9530  C CD1 . LEU D 1 113 ? -14.963 -59.900 65.507  1.00 31.38  ? 113 LEU D CD1 1 
ATOM 9531  C CD2 . LEU D 1 113 ? -13.772 -58.181 66.877  1.00 32.76  ? 113 LEU D CD2 1 
ATOM 9532  N N   . ILE D 1 114 ? -12.506 -62.008 64.354  1.00 31.44  ? 114 ILE D N   1 
ATOM 9533  C CA  . ILE D 1 114 ? -11.669 -61.862 63.166  1.00 36.38  ? 114 ILE D CA  1 
ATOM 9534  C C   . ILE D 1 114 ? -12.153 -60.626 62.416  1.00 41.12  ? 114 ILE D C   1 
ATOM 9535  O O   . ILE D 1 114 ? -13.226 -60.647 61.799  1.00 46.14  ? 114 ILE D O   1 
ATOM 9536  C CB  . ILE D 1 114 ? -11.709 -63.105 62.272  1.00 32.38  ? 114 ILE D CB  1 
ATOM 9537  C CG1 . ILE D 1 114 ? -11.153 -64.316 63.019  1.00 39.00  ? 114 ILE D CG1 1 
ATOM 9538  C CG2 . ILE D 1 114 ? -10.929 -62.861 60.994  1.00 36.52  ? 114 ILE D CG2 1 
ATOM 9539  C CD1 . ILE D 1 114 ? -11.128 -65.591 62.204  1.00 42.59  ? 114 ILE D CD1 1 
ATOM 9540  N N   . TYR D 1 115 ? -11.358 -59.563 62.457  1.00 33.57  ? 115 TYR D N   1 
ATOM 9541  C CA  . TYR D 1 115 ? -11.741 -58.258 61.936  1.00 42.72  ? 115 TYR D CA  1 
ATOM 9542  C C   . TYR D 1 115 ? -10.970 -57.936 60.662  1.00 41.82  ? 115 TYR D C   1 
ATOM 9543  O O   . TYR D 1 115 ? -9.999  -58.605 60.299  1.00 37.40  ? 115 TYR D O   1 
ATOM 9544  C CB  . TYR D 1 115 ? -11.516 -57.173 62.996  1.00 45.04  ? 115 TYR D CB  1 
ATOM 9545  C CG  . TYR D 1 115 ? -10.076 -57.000 63.427  1.00 46.36  ? 115 TYR D CG  1 
ATOM 9546  C CD1 . TYR D 1 115 ? -9.498  -57.848 64.369  1.00 43.22  ? 115 TYR D CD1 1 
ATOM 9547  C CD2 . TYR D 1 115 ? -9.299  -55.973 62.909  1.00 45.72  ? 115 TYR D CD2 1 
ATOM 9548  C CE1 . TYR D 1 115 ? -8.181  -57.684 64.766  1.00 43.65  ? 115 TYR D CE1 1 
ATOM 9549  C CE2 . TYR D 1 115 ? -7.985  -55.801 63.300  1.00 50.51  ? 115 TYR D CE2 1 
ATOM 9550  C CZ  . TYR D 1 115 ? -7.432  -56.657 64.229  1.00 53.81  ? 115 TYR D CZ  1 
ATOM 9551  O OH  . TYR D 1 115 ? -6.120  -56.486 64.615  1.00 46.42  ? 115 TYR D OH  1 
ATOM 9552  N N   . ASP D 1 116 ? -11.423 -56.887 59.978  1.00 40.54  ? 116 ASP D N   1 
ATOM 9553  C CA  . ASP D 1 116 ? -10.824 -56.455 58.724  1.00 46.06  ? 116 ASP D CA  1 
ATOM 9554  C C   . ASP D 1 116 ? -9.940  -55.231 58.957  1.00 46.13  ? 116 ASP D C   1 
ATOM 9555  O O   . ASP D 1 116 ? -9.432  -55.022 60.062  1.00 45.50  ? 116 ASP D O   1 
ATOM 9556  C CB  . ASP D 1 116 ? -11.924 -56.168 57.692  1.00 55.74  ? 116 ASP D CB  1 
ATOM 9557  C CG  . ASP D 1 116 ? -11.498 -56.487 56.274  1.00 51.04  ? 116 ASP D CG  1 
ATOM 9558  O OD1 . ASP D 1 116 ? -10.284 -56.448 55.997  1.00 43.76  ? 116 ASP D OD1 1 
ATOM 9559  O OD2 . ASP D 1 116 ? -12.378 -56.778 55.438  1.00 51.95  ? 116 ASP D OD2 1 
ATOM 9560  N N   . PHE D 1 117 ? -9.759  -54.404 57.928  1.00 48.63  ? 117 PHE D N   1 
ATOM 9561  C CA  . PHE D 1 117 ? -8.749  -53.353 57.988  1.00 53.46  ? 117 PHE D CA  1 
ATOM 9562  C C   . PHE D 1 117 ? -9.296  -52.004 58.422  1.00 53.36  ? 117 PHE D C   1 
ATOM 9563  O O   . PHE D 1 117 ? -8.571  -51.221 59.051  1.00 53.27  ? 117 PHE D O   1 
ATOM 9564  C CB  . PHE D 1 117 ? -8.067  -53.195 56.627  1.00 47.36  ? 117 PHE D CB  1 
ATOM 9565  C CG  . PHE D 1 117 ? -8.976  -52.678 55.544  1.00 50.01  ? 117 PHE D CG  1 
ATOM 9566  C CD1 . PHE D 1 117 ? -9.804  -53.541 54.849  1.00 55.46  ? 117 PHE D CD1 1 
ATOM 9567  C CD2 . PHE D 1 117 ? -8.987  -51.332 55.213  1.00 50.69  ? 117 PHE D CD2 1 
ATOM 9568  C CE1 . PHE D 1 117 ? -10.634 -53.073 53.849  1.00 60.74  ? 117 PHE D CE1 1 
ATOM 9569  C CE2 . PHE D 1 117 ? -9.817  -50.857 54.214  1.00 57.22  ? 117 PHE D CE2 1 
ATOM 9570  C CZ  . PHE D 1 117 ? -10.641 -51.729 53.531  1.00 63.15  ? 117 PHE D CZ  1 
ATOM 9571  N N   . ASN D 1 118 ? -10.543 -51.705 58.094  1.00 54.71  ? 118 ASN D N   1 
ATOM 9572  C CA  . ASN D 1 118 ? -11.067 -50.361 58.296  1.00 65.17  ? 118 ASN D CA  1 
ATOM 9573  C C   . ASN D 1 118 ? -12.036 -50.195 59.466  1.00 71.99  ? 118 ASN D C   1 
ATOM 9574  O O   . ASN D 1 118 ? -12.212 -49.059 59.923  1.00 79.97  ? 118 ASN D O   1 
ATOM 9575  C CB  . ASN D 1 118 ? -11.764 -49.862 57.029  1.00 71.23  ? 118 ASN D CB  1 
ATOM 9576  C CG  . ASN D 1 118 ? -11.762 -48.350 56.940  1.00 85.90  ? 118 ASN D CG  1 
ATOM 9577  O OD1 . ASN D 1 118 ? -10.816 -47.704 57.393  1.00 88.77  ? 118 ASN D OD1 1 
ATOM 9578  N ND2 . ASN D 1 118 ? -12.816 -47.777 56.372  1.00 84.48  ? 118 ASN D ND2 1 
ATOM 9579  N N   . PRO D 1 119 ? -12.720 -51.247 59.945  1.00 58.11  ? 119 PRO D N   1 
ATOM 9580  C CA  . PRO D 1 119 ? -13.568 -51.068 61.139  1.00 61.59  ? 119 PRO D CA  1 
ATOM 9581  C C   . PRO D 1 119 ? -12.900 -50.308 62.284  1.00 62.99  ? 119 PRO D C   1 
ATOM 9582  O O   . PRO D 1 119 ? -13.605 -49.651 63.063  1.00 71.87  ? 119 PRO D O   1 
ATOM 9583  C CB  . PRO D 1 119 ? -13.929 -52.513 61.512  1.00 66.63  ? 119 PRO D CB  1 
ATOM 9584  C CG  . PRO D 1 119 ? -14.077 -53.181 60.172  1.00 61.27  ? 119 PRO D CG  1 
ATOM 9585  C CD  . PRO D 1 119 ? -13.036 -52.519 59.266  1.00 51.10  ? 119 PRO D CD  1 
ATOM 9586  N N   . SER D 1 120 ? -11.570 -50.314 62.388  1.00 52.96  ? 120 SER D N   1 
ATOM 9587  C CA  . SER D 1 120 ? -10.846 -49.475 63.393  1.00 56.87  ? 120 SER D CA  1 
ATOM 9588  C C   . SER D 1 120 ? -11.217 -49.778 64.851  1.00 60.89  ? 120 SER D C   1 
ATOM 9589  O O   . SER D 1 120 ? -10.314 -50.096 65.634  1.00 61.32  ? 120 SER D O   1 
ATOM 9590  C CB  . SER D 1 120 ? -11.056 -48.021 63.109  1.00 57.71  ? 120 SER D CB  1 
ATOM 9591  O OG  . SER D 1 120 ? -10.642 -47.225 64.205  1.00 70.33  ? 120 SER D OG  1 
ATOM 9592  N N   . TRP D 1 121 ? -12.484 -49.617 65.214  1.00 59.65  ? 121 TRP D N   1 
ATOM 9593  C CA  . TRP D 1 121 ? -12.915 -49.808 66.619  1.00 59.56  ? 121 TRP D CA  1 
ATOM 9594  C C   . TRP D 1 121 ? -13.050 -51.295 66.929  1.00 60.53  ? 121 TRP D C   1 
ATOM 9595  O O   . TRP D 1 121 ? -13.149 -51.646 68.109  1.00 62.15  ? 121 TRP D O   1 
ATOM 9596  C CB  . TRP D 1 121 ? -14.225 -49.059 66.863  1.00 63.48  ? 121 TRP D CB  1 
ATOM 9597  C CG  . TRP D 1 121 ? -15.279 -49.220 65.810  1.00 65.33  ? 121 TRP D CG  1 
ATOM 9598  C CD1 . TRP D 1 121 ? -15.741 -48.252 64.967  1.00 57.33  ? 121 TRP D CD1 1 
ATOM 9599  C CD2 . TRP D 1 121 ? -16.051 -50.398 65.526  1.00 64.37  ? 121 TRP D CD2 1 
ATOM 9600  N NE1 . TRP D 1 121 ? -16.722 -48.755 64.157  1.00 67.97  ? 121 TRP D NE1 1 
ATOM 9601  C CE2 . TRP D 1 121 ? -16.936 -50.069 64.478  1.00 67.03  ? 121 TRP D CE2 1 
ATOM 9602  C CE3 . TRP D 1 121 ? -16.075 -51.698 66.039  1.00 59.68  ? 121 TRP D CE3 1 
ATOM 9603  C CZ2 . TRP D 1 121 ? -17.828 -50.992 63.938  1.00 65.14  ? 121 TRP D CZ2 1 
ATOM 9604  C CZ3 . TRP D 1 121 ? -16.955 -52.610 65.503  1.00 70.94  ? 121 TRP D CZ3 1 
ATOM 9605  C CH2 . TRP D 1 121 ? -17.818 -52.260 64.468  1.00 67.92  ? 121 TRP D CH2 1 
ATOM 9606  N N   . ALA D 1 122 ? -13.039 -52.128 65.900  1.00 54.77  ? 122 ALA D N   1 
ATOM 9607  C CA  . ALA D 1 122 ? -13.236 -53.575 66.103  1.00 55.43  ? 122 ALA D CA  1 
ATOM 9608  C C   . ALA D 1 122 ? -12.251 -54.078 67.148  1.00 52.36  ? 122 ALA D C   1 
ATOM 9609  O O   . ALA D 1 122 ? -12.696 -54.667 68.134  1.00 57.89  ? 122 ALA D O   1 
ATOM 9610  C CB  . ALA D 1 122 ? -13.046 -54.279 64.791  1.00 54.48  ? 122 ALA D CB  1 
ATOM 9611  N N   . PRO D 1 123 ? -10.936 -53.869 66.981  1.00 51.89  ? 123 PRO D N   1 
ATOM 9612  C CA  . PRO D 1 123 ? -9.978  -54.417 67.929  1.00 57.95  ? 123 PRO D CA  1 
ATOM 9613  C C   . PRO D 1 123 ? -10.206 -53.843 69.336  1.00 56.10  ? 123 PRO D C   1 
ATOM 9614  O O   . PRO D 1 123 ? -10.051 -54.569 70.294  1.00 57.84  ? 123 PRO D O   1 
ATOM 9615  C CB  . PRO D 1 123 ? -8.629  -54.028 67.302  1.00 59.14  ? 123 PRO D CB  1 
ATOM 9616  C CG  . PRO D 1 123 ? -8.933  -52.850 66.421  1.00 61.88  ? 123 PRO D CG  1 
ATOM 9617  C CD  . PRO D 1 123 ? -10.311 -53.143 65.879  1.00 50.18  ? 123 PRO D CD  1 
ATOM 9618  N N   . GLU D 1 124 ? -10.603 -52.578 69.423  1.00 52.23  ? 124 GLU D N   1 
ATOM 9619  C CA  . GLU D 1 124 ? -10.785 -51.907 70.733  1.00 53.56  ? 124 GLU D CA  1 
ATOM 9620  C C   . GLU D 1 124 ? -12.034 -52.429 71.451  1.00 57.81  ? 124 GLU D C   1 
ATOM 9621  O O   . GLU D 1 124 ? -11.935 -52.707 72.652  1.00 63.52  ? 124 GLU D O   1 
ATOM 9622  C CB  . GLU D 1 124 ? -10.891 -50.406 70.483  1.00 57.86  ? 124 GLU D CB  1 
ATOM 9623  C CG  . GLU D 1 124 ? -10.006 -49.920 69.350  1.00 64.80  ? 124 GLU D CG  1 
ATOM 9624  C CD  . GLU D 1 124 ? -10.258 -48.491 68.900  1.00 75.77  ? 124 GLU D CD  1 
ATOM 9625  O OE1 . GLU D 1 124 ? -11.124 -47.827 69.500  1.00 68.31  ? 124 GLU D OE1 1 
ATOM 9626  O OE2 . GLU D 1 124 ? -9.596  -48.046 67.944  1.00 84.59  ? 124 GLU D OE2 1 
ATOM 9627  N N   . ILE D 1 125 ? -13.155 -52.549 70.744  1.00 49.22  ? 125 ILE D N   1 
ATOM 9628  C CA  . ILE D 1 125 ? -14.441 -53.002 71.345  1.00 52.52  ? 125 ILE D CA  1 
ATOM 9629  C C   . ILE D 1 125 ? -14.316 -54.471 71.739  1.00 46.57  ? 125 ILE D C   1 
ATOM 9630  O O   . ILE D 1 125 ? -14.942 -54.874 72.728  1.00 47.35  ? 125 ILE D O   1 
ATOM 9631  C CB  . ILE D 1 125 ? -15.603 -52.768 70.362  1.00 59.22  ? 125 ILE D CB  1 
ATOM 9632  C CG1 . ILE D 1 125 ? -16.176 -51.355 70.481  1.00 53.77  ? 125 ILE D CG1 1 
ATOM 9633  C CG2 . ILE D 1 125 ? -16.685 -53.821 70.537  1.00 52.72  ? 125 ILE D CG2 1 
ATOM 9634  C CD1 . ILE D 1 125 ? -15.275 -50.277 69.928  1.00 56.90  ? 125 ILE D CD1 1 
ATOM 9635  N N   . ALA D 1 126 ? -13.526 -55.236 70.994  1.00 41.34  ? 126 ALA D N   1 
ATOM 9636  C CA  . ALA D 1 126 ? -13.332 -56.668 71.308  1.00 46.19  ? 126 ALA D CA  1 
ATOM 9637  C C   . ALA D 1 126 ? -12.582 -56.810 72.631  1.00 53.27  ? 126 ALA D C   1 
ATOM 9638  O O   . ALA D 1 126 ? -12.911 -57.710 73.414  1.00 48.16  ? 126 ALA D O   1 
ATOM 9639  C CB  . ALA D 1 126 ? -12.568 -57.303 70.190  1.00 34.13  ? 126 ALA D CB  1 
ATOM 9640  N N   . SER D 1 127 ? -11.598 -55.950 72.849  1.00 54.19  ? 127 SER D N   1 
ATOM 9641  C CA  . SER D 1 127 ? -10.795 -56.001 74.089  1.00 54.53  ? 127 SER D CA  1 
ATOM 9642  C C   . SER D 1 127 ? -11.625 -55.515 75.280  1.00 51.89  ? 127 SER D C   1 
ATOM 9643  O O   . SER D 1 127 ? -11.311 -55.902 76.407  1.00 62.87  ? 127 SER D O   1 
ATOM 9644  C CB  . SER D 1 127 ? -9.556  -55.189 73.905  1.00 60.37  ? 127 SER D CB  1 
ATOM 9645  O OG  . SER D 1 127 ? -8.910  -55.539 72.693  1.00 61.63  ? 127 SER D OG  1 
ATOM 9646  N N   . SER D 1 128 ? -12.625 -54.683 75.030  1.00 49.97  ? 128 SER D N   1 
ATOM 9647  C CA  . SER D 1 128 ? -13.517 -54.206 76.106  1.00 50.67  ? 128 SER D CA  1 
ATOM 9648  C C   . SER D 1 128 ? -14.431 -55.346 76.543  1.00 48.76  ? 128 SER D C   1 
ATOM 9649  O O   . SER D 1 128 ? -15.074 -55.223 77.587  1.00 49.94  ? 128 SER D O   1 
ATOM 9650  C CB  . SER D 1 128 ? -14.302 -53.040 75.633  1.00 52.78  ? 128 SER D CB  1 
ATOM 9651  O OG  . SER D 1 128 ? -15.234 -53.433 74.642  1.00 67.05  ? 128 SER D OG  1 
ATOM 9652  N N   . HIS D 1 129 ? -14.511 -56.402 75.748  1.00 46.93  ? 129 HIS D N   1 
ATOM 9653  C CA  . HIS D 1 129 ? -15.295 -57.588 76.165  1.00 44.14  ? 129 HIS D CA  1 
ATOM 9654  C C   . HIS D 1 129 ? -14.308 -58.719 76.460  1.00 43.07  ? 129 HIS D C   1 
ATOM 9655  O O   . HIS D 1 129 ? -14.749 -59.871 76.614  1.00 45.22  ? 129 HIS D O   1 
ATOM 9656  C CB  . HIS D 1 129 ? -16.325 -57.954 75.097  1.00 42.02  ? 129 HIS D CB  1 
ATOM 9657  C CG  . HIS D 1 129 ? -17.338 -56.905 74.785  1.00 39.51  ? 129 HIS D CG  1 
ATOM 9658  N ND1 . HIS D 1 129 ? -18.677 -57.074 75.056  1.00 36.77  ? 129 HIS D ND1 1 
ATOM 9659  C CD2 . HIS D 1 129 ? -17.222 -55.696 74.235  1.00 48.81  ? 129 HIS D CD2 1 
ATOM 9660  C CE1 . HIS D 1 129 ? -19.336 -55.993 74.677  1.00 40.55  ? 129 HIS D CE1 1 
ATOM 9661  N NE2 . HIS D 1 129 ? -18.471 -55.143 74.174  1.00 43.19  ? 129 HIS D NE2 1 
ATOM 9662  N N   . ASN D 1 130 ? -13.014 -58.397 76.527  1.00 44.12  ? 130 ASN D N   1 
ATOM 9663  C CA  . ASN D 1 130 ? -11.952 -59.397 76.816  1.00 44.58  ? 130 ASN D CA  1 
ATOM 9664  C C   . ASN D 1 130 ? -11.984 -60.455 75.719  1.00 40.09  ? 130 ASN D C   1 
ATOM 9665  O O   . ASN D 1 130 ? -11.791 -61.633 76.035  1.00 40.68  ? 130 ASN D O   1 
ATOM 9666  C CB  . ASN D 1 130 ? -12.080 -59.940 78.240  1.00 49.53  ? 130 ASN D CB  1 
ATOM 9667  C CG  . ASN D 1 130 ? -10.818 -60.606 78.746  1.00 56.48  ? 130 ASN D CG  1 
ATOM 9668  O OD1 . ASN D 1 130 ? -9.756  -59.987 78.781  1.00 60.47  ? 130 ASN D OD1 1 
ATOM 9669  N ND2 . ASN D 1 130 ? -10.925 -61.861 79.147  1.00 58.15  ? 130 ASN D ND2 1 
ATOM 9670  N N   . ILE D 1 131 ? -12.214 -60.029 74.476  1.00 40.77  ? 131 ILE D N   1 
ATOM 9671  C CA  . ILE D 1 131 ? -12.207 -60.962 73.354  1.00 39.77  ? 131 ILE D CA  1 
ATOM 9672  C C   . ILE D 1 131 ? -10.914 -60.751 72.576  1.00 44.27  ? 131 ILE D C   1 
ATOM 9673  O O   . ILE D 1 131 ? -10.656 -59.630 72.115  1.00 43.01  ? 131 ILE D O   1 
ATOM 9674  C CB  . ILE D 1 131 ? -13.432 -60.773 72.449  1.00 43.45  ? 131 ILE D CB  1 
ATOM 9675  C CG1 . ILE D 1 131 ? -14.722 -60.977 73.240  1.00 46.46  ? 131 ILE D CG1 1 
ATOM 9676  C CG2 . ILE D 1 131 ? -13.382 -61.738 71.275  1.00 45.36  ? 131 ILE D CG2 1 
ATOM 9677  C CD1 . ILE D 1 131 ? -15.965 -60.816 72.404  1.00 39.32  ? 131 ILE D CD1 1 
ATOM 9678  N N   . PRO D 1 132 ? -10.083 -61.775 72.402  1.00 44.64  ? 132 PRO D N   1 
ATOM 9679  C CA  . PRO D 1 132 ? -8.877  -61.608 71.584  1.00 50.16  ? 132 PRO D CA  1 
ATOM 9680  C C   . PRO D 1 132 ? -9.236  -61.380 70.124  1.00 44.21  ? 132 PRO D C   1 
ATOM 9681  O O   . PRO D 1 132 ? -10.116 -62.038 69.569  1.00 47.27  ? 132 PRO D O   1 
ATOM 9682  C CB  . PRO D 1 132 ? -8.128  -62.932 71.779  1.00 48.69  ? 132 PRO D CB  1 
ATOM 9683  C CG  . PRO D 1 132 ? -9.190  -63.910 72.153  1.00 42.06  ? 132 PRO D CG  1 
ATOM 9684  C CD  . PRO D 1 132 ? -10.196 -63.135 72.954  1.00 43.78  ? 132 PRO D CD  1 
ATOM 9685  N N   . ALA D 1 133 ? -8.541  -60.430 69.507  1.00 40.52  ? 133 ALA D N   1 
ATOM 9686  C CA  . ALA D 1 133 ? -8.828  -59.993 68.147  1.00 32.82  ? 133 ALA D CA  1 
ATOM 9687  C C   . ALA D 1 133 ? -7.692  -60.401 67.219  1.00 36.68  ? 133 ALA D C   1 
ATOM 9688  O O   . ALA D 1 133 ? -6.524  -60.099 67.490  1.00 47.38  ? 133 ALA D O   1 
ATOM 9689  C CB  . ALA D 1 133 ? -9.037  -58.480 68.100  1.00 43.51  ? 133 ALA D CB  1 
ATOM 9690  N N   . VAL D 1 134 ? -8.038  -61.085 66.130  1.00 41.07  ? 134 VAL D N   1 
ATOM 9691  C CA  . VAL D 1 134 ? -7.082  -61.524 65.120  1.00 46.78  ? 134 VAL D CA  1 
ATOM 9692  C C   . VAL D 1 134 ? -7.432  -60.851 63.799  1.00 37.57  ? 134 VAL D C   1 
ATOM 9693  O O   . VAL D 1 134 ? -8.603  -60.795 63.412  1.00 38.52  ? 134 VAL D O   1 
ATOM 9694  C CB  . VAL D 1 134 ? -7.081  -63.060 64.963  1.00 44.32  ? 134 VAL D CB  1 
ATOM 9695  C CG1 . VAL D 1 134 ? -6.228  -63.481 63.773  1.00 38.80  ? 134 VAL D CG1 1 
ATOM 9696  C CG2 . VAL D 1 134 ? -6.587  -63.725 66.240  1.00 45.93  ? 134 VAL D CG2 1 
ATOM 9697  N N   . TYR D 1 135 ? -6.411  -60.350 63.108  1.00 37.06  ? 135 TYR D N   1 
ATOM 9698  C CA  . TYR D 1 135 ? -6.601  -59.633 61.852  1.00 36.05  ? 135 TYR D CA  1 
ATOM 9699  C C   . TYR D 1 135 ? -6.543  -60.589 60.666  1.00 38.76  ? 135 TYR D C   1 
ATOM 9700  O O   . TYR D 1 135 ? -5.744  -61.530 60.644  1.00 38.30  ? 135 TYR D O   1 
ATOM 9701  C CB  . TYR D 1 135 ? -5.541  -58.539 61.703  1.00 38.22  ? 135 TYR D CB  1 
ATOM 9702  C CG  . TYR D 1 135 ? -5.517  -57.846 60.357  1.00 40.39  ? 135 TYR D CG  1 
ATOM 9703  C CD1 . TYR D 1 135 ? -6.628  -57.164 59.879  1.00 45.75  ? 135 TYR D CD1 1 
ATOM 9704  C CD2 . TYR D 1 135 ? -4.367  -57.846 59.578  1.00 41.27  ? 135 TYR D CD2 1 
ATOM 9705  C CE1 . TYR D 1 135 ? -6.600  -56.522 58.653  1.00 50.48  ? 135 TYR D CE1 1 
ATOM 9706  C CE2 . TYR D 1 135 ? -4.328  -57.206 58.356  1.00 46.45  ? 135 TYR D CE2 1 
ATOM 9707  C CZ  . TYR D 1 135 ? -5.445  -56.543 57.897  1.00 56.60  ? 135 TYR D CZ  1 
ATOM 9708  O OH  . TYR D 1 135 ? -5.412  -55.905 56.677  1.00 49.59  ? 135 TYR D OH  1 
ATOM 9709  N N   . PHE D 1 136 ? -7.402  -60.339 59.681  1.00 41.19  ? 136 PHE D N   1 
ATOM 9710  C CA  . PHE D 1 136 ? -7.481  -61.128 58.457  1.00 40.42  ? 136 PHE D CA  1 
ATOM 9711  C C   . PHE D 1 136 ? -7.068  -60.232 57.295  1.00 45.23  ? 136 PHE D C   1 
ATOM 9712  O O   . PHE D 1 136 ? -7.790  -59.295 56.940  1.00 50.88  ? 136 PHE D O   1 
ATOM 9713  C CB  . PHE D 1 136 ? -8.890  -61.682 58.252  1.00 49.28  ? 136 PHE D CB  1 
ATOM 9714  C CG  . PHE D 1 136 ? -9.017  -62.637 57.095  1.00 41.66  ? 136 PHE D CG  1 
ATOM 9715  C CD1 . PHE D 1 136 ? -7.898  -63.240 56.539  1.00 45.02  ? 136 PHE D CD1 1 
ATOM 9716  C CD2 . PHE D 1 136 ? -10.260 -62.927 56.556  1.00 40.83  ? 136 PHE D CD2 1 
ATOM 9717  C CE1 . PHE D 1 136 ? -8.020  -64.112 55.473  1.00 45.27  ? 136 PHE D CE1 1 
ATOM 9718  C CE2 . PHE D 1 136 ? -10.386 -63.796 55.492  1.00 47.68  ? 136 PHE D CE2 1 
ATOM 9719  C CZ  . PHE D 1 136 ? -9.266  -64.390 54.948  1.00 44.39  ? 136 PHE D CZ  1 
ATOM 9720  N N   . LEU D 1 137 ? -5.914  -60.524 56.700  1.00 39.75  ? 137 LEU D N   1 
ATOM 9721  C CA  . LEU D 1 137 ? -5.393  -59.769 55.566  1.00 39.16  ? 137 LEU D CA  1 
ATOM 9722  C C   . LEU D 1 137 ? -5.723  -60.533 54.288  1.00 41.20  ? 137 LEU D C   1 
ATOM 9723  O O   . LEU D 1 137 ? -5.246  -61.653 54.088  1.00 37.13  ? 137 LEU D O   1 
ATOM 9724  C CB  . LEU D 1 137 ? -3.887  -59.556 55.705  1.00 43.93  ? 137 LEU D CB  1 
ATOM 9725  C CG  . LEU D 1 137 ? -3.168  -58.794 54.593  1.00 46.94  ? 137 LEU D CG  1 
ATOM 9726  C CD1 . LEU D 1 137 ? -3.146  -57.300 54.877  1.00 46.44  ? 137 LEU D CD1 1 
ATOM 9727  C CD2 . LEU D 1 137 ? -1.761  -59.334 54.413  1.00 48.17  ? 137 LEU D CD2 1 
ATOM 9728  N N   . THR D 1 138 ? -6.541  -59.927 53.429  1.00 45.94  ? 138 THR D N   1 
ATOM 9729  C CA  . THR D 1 138 ? -6.958  -60.553 52.180  1.00 51.44  ? 138 THR D CA  1 
ATOM 9730  C C   . THR D 1 138 ? -6.115  -60.112 50.995  1.00 56.63  ? 138 THR D C   1 
ATOM 9731  O O   . THR D 1 138 ? -6.505  -60.346 49.848  1.00 60.04  ? 138 THR D O   1 
ATOM 9732  C CB  . THR D 1 138 ? -8.431  -60.250 51.901  1.00 48.93  ? 138 THR D CB  1 
ATOM 9733  O OG1 . THR D 1 138 ? -8.606  -58.839 51.724  1.00 58.17  ? 138 THR D OG1 1 
ATOM 9734  C CG2 . THR D 1 138 ? -9.293  -60.718 53.066  1.00 44.01  ? 138 THR D CG2 1 
ATOM 9735  N N   . THR D 1 139 ? -4.972  -59.484 51.249  1.00 55.51  ? 139 THR D N   1 
ATOM 9736  C CA  . THR D 1 139 ? -4.087  -58.973 50.217  1.00 54.56  ? 139 THR D CA  1 
ATOM 9737  C C   . THR D 1 139 ? -2.745  -59.693 50.314  1.00 54.23  ? 139 THR D C   1 
ATOM 9738  O O   . THR D 1 139 ? -2.435  -60.331 51.323  1.00 53.67  ? 139 THR D O   1 
ATOM 9739  C CB  . THR D 1 139 ? -3.914  -57.452 50.369  1.00 56.45  ? 139 THR D CB  1 
ATOM 9740  O OG1 . THR D 1 139 ? -5.195  -56.850 50.593  1.00 56.02  ? 139 THR D OG1 1 
ATOM 9741  C CG2 . THR D 1 139 ? -3.301  -56.836 49.125  1.00 68.55  ? 139 THR D CG2 1 
ATOM 9742  N N   . ALA D 1 140 ? -1.968  -59.609 49.237  1.00 55.37  ? 140 ALA D N   1 
ATOM 9743  C CA  . ALA D 1 140 ? -0.637  -60.201 49.218  1.00 47.20  ? 140 ALA D CA  1 
ATOM 9744  C C   . ALA D 1 140 ? 0.222   -59.640 50.345  1.00 45.43  ? 140 ALA D C   1 
ATOM 9745  O O   . ALA D 1 140 ? 0.056   -58.495 50.777  1.00 42.99  ? 140 ALA D O   1 
ATOM 9746  C CB  . ALA D 1 140 ? 0.039   -59.940 47.872  1.00 61.82  ? 140 ALA D CB  1 
ATOM 9747  N N   . ALA D 1 141 ? 1.156   -60.465 50.823  1.00 48.46  ? 141 ALA D N   1 
ATOM 9748  C CA  . ALA D 1 141 ? 2.011   -60.051 51.929  1.00 45.99  ? 141 ALA D CA  1 
ATOM 9749  C C   . ALA D 1 141 ? 3.022   -58.994 51.502  1.00 46.71  ? 141 ALA D C   1 
ATOM 9750  O O   . ALA D 1 141 ? 3.392   -58.140 52.312  1.00 41.57  ? 141 ALA D O   1 
ATOM 9751  C CB  . ALA D 1 141 ? 2.730   -61.260 52.522  1.00 51.23  ? 141 ALA D CB  1 
ATOM 9752  N N   . ALA D 1 142 ? 3.477   -59.027 50.246  1.00 45.89  ? 142 ALA D N   1 
ATOM 9753  C CA  . ALA D 1 142 ? 4.512   -58.095 49.807  1.00 49.79  ? 142 ALA D CA  1 
ATOM 9754  C C   . ALA D 1 142 ? 3.987   -56.667 49.724  1.00 51.26  ? 142 ALA D C   1 
ATOM 9755  O O   . ALA D 1 142 ? 4.666   -55.718 50.146  1.00 57.04  ? 142 ALA D O   1 
ATOM 9756  C CB  . ALA D 1 142 ? 5.063   -58.532 48.449  1.00 48.49  ? 142 ALA D CB  1 
ATOM 9757  N N   . SER D 1 143 ? 2.791   -56.497 49.159  1.00 44.97  ? 143 SER D N   1 
ATOM 9758  C CA  . SER D 1 143 ? 2.221   -55.165 49.001  1.00 46.35  ? 143 SER D CA  1 
ATOM 9759  C C   . SER D 1 143 ? 2.051   -54.477 50.348  1.00 45.33  ? 143 SER D C   1 
ATOM 9760  O O   . SER D 1 143 ? 2.293   -53.271 50.471  1.00 52.24  ? 143 SER D O   1 
ATOM 9761  C CB  . SER D 1 143 ? 0.886   -55.260 48.265  1.00 61.78  ? 143 SER D CB  1 
ATOM 9762  O OG  . SER D 1 143 ? 1.034   -55.992 47.059  1.00 73.47  ? 143 SER D OG  1 
ATOM 9763  N N   . SER D 1 144 ? 1.643   -55.229 51.373  1.00 47.63  ? 144 SER D N   1 
ATOM 9764  C CA  . SER D 1 144 ? 1.542   -54.661 52.713  1.00 48.85  ? 144 SER D CA  1 
ATOM 9765  C C   . SER D 1 144 ? 2.916   -54.486 53.347  1.00 51.98  ? 144 SER D C   1 
ATOM 9766  O O   . SER D 1 144 ? 3.136   -53.532 54.104  1.00 53.61  ? 144 SER D O   1 
ATOM 9767  C CB  . SER D 1 144 ? 0.666   -55.548 53.593  1.00 45.23  ? 144 SER D CB  1 
ATOM 9768  O OG  . SER D 1 144 ? -0.568  -55.836 52.958  1.00 52.97  ? 144 SER D OG  1 
ATOM 9769  N N   . SER D 1 145 ? 3.838   -55.411 53.052  1.00 48.04  ? 145 SER D N   1 
ATOM 9770  C CA  . SER D 1 145 ? 5.202   -55.322 53.560  1.00 44.38  ? 145 SER D CA  1 
ATOM 9771  C C   . SER D 1 145 ? 5.868   -54.025 53.145  1.00 51.97  ? 145 SER D C   1 
ATOM 9772  O O   . SER D 1 145 ? 6.675   -53.479 53.902  1.00 64.04  ? 145 SER D O   1 
ATOM 9773  C CB  . SER D 1 145 ? 6.019   -56.517 53.068  1.00 43.29  ? 145 SER D CB  1 
ATOM 9774  O OG  . SER D 1 145 ? 5.468   -57.736 53.532  1.00 63.55  ? 145 SER D OG  1 
ATOM 9775  N N   . ILE D 1 146 ? 5.545   -53.521 51.954  1.00 47.51  ? 146 ILE D N   1 
ATOM 9776  C CA  . ILE D 1 146 ? 6.061   -52.232 51.490  1.00 49.07  ? 146 ILE D CA  1 
ATOM 9777  C C   . ILE D 1 146 ? 5.863   -51.175 52.573  1.00 56.01  ? 146 ILE D C   1 
ATOM 9778  O O   . ILE D 1 146 ? 6.831   -50.680 53.171  1.00 58.37  ? 146 ILE D O   1 
ATOM 9779  C CB  . ILE D 1 146 ? 5.380   -51.800 50.177  1.00 53.06  ? 146 ILE D CB  1 
ATOM 9780  C CG1 . ILE D 1 146 ? 5.566   -52.867 49.095  1.00 58.86  ? 146 ILE D CG1 1 
ATOM 9781  C CG2 . ILE D 1 146 ? 5.933   -50.468 49.704  1.00 54.08  ? 146 ILE D CG2 1 
ATOM 9782  C CD1 . ILE D 1 146 ? 7.006   -53.216 48.822  1.00 56.92  ? 146 ILE D CD1 1 
ATOM 9783  N N   . GLY D 1 147 ? 4.600   -50.844 52.853  1.00 64.06  ? 147 GLY D N   1 
ATOM 9784  C CA  . GLY D 1 147 ? 4.309   -49.810 53.830  1.00 63.50  ? 147 GLY D CA  1 
ATOM 9785  C C   . GLY D 1 147 ? 4.699   -50.178 55.248  1.00 58.40  ? 147 GLY D C   1 
ATOM 9786  O O   . GLY D 1 147 ? 5.128   -49.312 56.022  1.00 66.54  ? 147 GLY D O   1 
ATOM 9787  N N   . LEU D 1 148 ? 4.563   -51.454 55.618  1.00 57.38  ? 148 LEU D N   1 
ATOM 9788  C CA  . LEU D 1 148 ? 4.902   -51.836 56.985  1.00 54.22  ? 148 LEU D CA  1 
ATOM 9789  C C   . LEU D 1 148 ? 6.396   -51.677 57.242  1.00 57.90  ? 148 LEU D C   1 
ATOM 9790  O O   . LEU D 1 148 ? 6.804   -51.278 58.341  1.00 57.78  ? 148 LEU D O   1 
ATOM 9791  C CB  . LEU D 1 148 ? 4.457   -53.267 57.270  1.00 50.85  ? 148 LEU D CB  1 
ATOM 9792  C CG  . LEU D 1 148 ? 4.320   -53.600 58.756  1.00 46.11  ? 148 LEU D CG  1 
ATOM 9793  C CD1 . LEU D 1 148 ? 3.418   -52.592 59.453  1.00 55.79  ? 148 LEU D CD1 1 
ATOM 9794  C CD2 . LEU D 1 148 ? 3.783   -55.010 58.937  1.00 46.19  ? 148 LEU D CD2 1 
ATOM 9795  N N   . HIS D 1 149 ? 7.244   -51.917 56.241  1.00 53.86  ? 149 HIS D N   1 
ATOM 9796  C CA  . HIS D 1 149 ? 8.713   -51.719 56.408  1.00 56.56  ? 149 HIS D CA  1 
ATOM 9797  C C   . HIS D 1 149 ? 9.028   -50.239 56.540  1.00 53.03  ? 149 HIS D C   1 
ATOM 9798  O O   . HIS D 1 149 ? 9.859   -49.893 57.363  1.00 57.21  ? 149 HIS D O   1 
ATOM 9799  C CB  . HIS D 1 149 ? 9.481   -52.266 55.205  1.00 51.30  ? 149 HIS D CB  1 
ATOM 9800  C CG  . HIS D 1 149 ? 10.957  -52.085 55.265  1.00 63.19  ? 149 HIS D CG  1 
ATOM 9801  N ND1 . HIS D 1 149 ? 11.787  -53.039 55.802  1.00 74.66  ? 149 HIS D ND1 1 
ATOM 9802  C CD2 . HIS D 1 149 ? 11.750  -51.082 54.844  1.00 59.62  ? 149 HIS D CD2 1 
ATOM 9803  C CE1 . HIS D 1 149 ? 13.031  -52.626 55.724  1.00 76.49  ? 149 HIS D CE1 1 
ATOM 9804  N NE2 . HIS D 1 149 ? 13.033  -51.428 55.148  1.00 75.00  ? 149 HIS D NE2 1 
ATOM 9805  N N   . ALA D 1 150 ? 8.351   -49.414 55.767  1.00 51.55  ? 150 ALA D N   1 
ATOM 9806  C CA  . ALA D 1 150 ? 8.633   -47.967 55.744  1.00 52.26  ? 150 ALA D CA  1 
ATOM 9807  C C   . ALA D 1 150 ? 8.373   -47.366 57.117  1.00 55.24  ? 150 ALA D C   1 
ATOM 9808  O O   . ALA D 1 150 ? 8.880   -46.276 57.387  1.00 65.15  ? 150 ALA D O   1 
ATOM 9809  C CB  . ALA D 1 150 ? 7.760   -47.323 54.716  1.00 58.77  ? 150 ALA D CB  1 
ATOM 9810  N N   . PHE D 1 151 ? 7.608   -48.079 57.949  1.00 50.04  ? 151 PHE D N   1 
ATOM 9811  C CA  . PHE D 1 151 ? 7.321   -47.613 59.329  1.00 57.96  ? 151 PHE D CA  1 
ATOM 9812  C C   . PHE D 1 151 ? 8.264   -48.334 60.296  1.00 59.95  ? 151 PHE D C   1 
ATOM 9813  O O   . PHE D 1 151 ? 8.931   -47.655 61.100  1.00 66.65  ? 151 PHE D O   1 
ATOM 9814  C CB  . PHE D 1 151 ? 5.856   -47.881 59.678  1.00 58.14  ? 151 PHE D CB  1 
ATOM 9815  C CG  . PHE D 1 151 ? 5.514   -47.716 61.137  1.00 67.25  ? 151 PHE D CG  1 
ATOM 9816  C CD1 . PHE D 1 151 ? 5.663   -46.493 61.769  1.00 80.76  ? 151 PHE D CD1 1 
ATOM 9817  C CD2 . PHE D 1 151 ? 5.047   -48.789 61.880  1.00 72.33  ? 151 PHE D CD2 1 
ATOM 9818  C CE1 . PHE D 1 151 ? 5.349   -46.345 63.108  1.00 85.98  ? 151 PHE D CE1 1 
ATOM 9819  C CE2 . PHE D 1 151 ? 4.735   -48.639 63.222  1.00 77.94  ? 151 PHE D CE2 1 
ATOM 9820  C CZ  . PHE D 1 151 ? 4.886   -47.418 63.834  1.00 73.88  ? 151 PHE D CZ  1 
ATOM 9821  N N   . LYS D 1 152 ? 8.244   -49.650 60.298  1.00 55.63  ? 152 LYS D N   1 
ATOM 9822  C CA  . LYS D 1 152 ? 9.056   -50.324 61.333  1.00 62.13  ? 152 LYS D CA  1 
ATOM 9823  C C   . LYS D 1 152 ? 10.517  -49.921 61.148  1.00 66.21  ? 152 LYS D C   1 
ATOM 9824  O O   . LYS D 1 152 ? 11.159  -49.545 62.142  1.00 73.03  ? 152 LYS D O   1 
ATOM 9825  C CB  . LYS D 1 152 ? 8.765   -51.823 61.347  1.00 63.81  ? 152 LYS D CB  1 
ATOM 9826  C CG  . LYS D 1 152 ? 7.312   -52.189 61.599  1.00 65.07  ? 152 LYS D CG  1 
ATOM 9827  C CD  . LYS D 1 152 ? 6.841   -51.813 62.981  1.00 61.63  ? 152 LYS D CD  1 
ATOM 9828  C CE  . LYS D 1 152 ? 5.372   -52.102 63.195  1.00 80.80  ? 152 LYS D CE  1 
ATOM 9829  N NZ  . LYS D 1 152 ? 4.999   -53.438 62.679  1.00 70.75  ? 152 LYS D NZ  1 
ATOM 9830  N N   . ASN D 1 153 ? 11.014  -50.000 59.920  1.00 62.67  ? 153 ASN D N   1 
ATOM 9831  C CA  . ASN D 1 153 ? 12.435  -49.677 59.651  1.00 65.26  ? 153 ASN D CA  1 
ATOM 9832  C C   . ASN D 1 153 ? 12.430  -48.488 58.699  1.00 69.20  ? 153 ASN D C   1 
ATOM 9833  O O   . ASN D 1 153 ? 12.475  -48.705 57.483  1.00 71.03  ? 153 ASN D O   1 
ATOM 9834  C CB  . ASN D 1 153 ? 13.137  -50.922 59.118  1.00 59.93  ? 153 ASN D CB  1 
ATOM 9835  C CG  . ASN D 1 153 ? 13.019  -52.103 60.055  1.00 63.21  ? 153 ASN D CG  1 
ATOM 9836  O OD1 . ASN D 1 153 ? 13.047  -51.943 61.271  1.00 58.11  ? 153 ASN D OD1 1 
ATOM 9837  N ND2 . ASN D 1 153 ? 12.896  -53.294 59.497  1.00 76.78  ? 153 ASN D ND2 1 
ATOM 9838  N N   . PRO D 1 154 ? 12.499  -47.237 59.188  1.00 71.10  ? 154 PRO D N   1 
ATOM 9839  C CA  . PRO D 1 154 ? 12.319  -46.087 58.308  1.00 74.30  ? 154 PRO D CA  1 
ATOM 9840  C C   . PRO D 1 154 ? 13.285  -45.937 57.128  1.00 80.07  ? 154 PRO D C   1 
ATOM 9841  O O   . PRO D 1 154 ? 12.816  -45.665 56.052  1.00 75.64  ? 154 PRO D O   1 
ATOM 9842  C CB  . PRO D 1 154 ? 12.554  -44.904 59.254  1.00 70.75  ? 154 PRO D CB  1 
ATOM 9843  C CG  . PRO D 1 154 ? 12.213  -45.446 60.620  1.00 74.83  ? 154 PRO D CG  1 
ATOM 9844  C CD  . PRO D 1 154 ? 12.711  -46.872 60.584  1.00 74.40  ? 154 PRO D CD  1 
ATOM 9845  N N   . GLY D 1 155 ? 14.580  -46.124 57.346  1.00 82.99  ? 155 GLY D N   1 
ATOM 9846  C CA  . GLY D 1 155 ? 15.537  -45.885 56.253  1.00 74.48  ? 155 GLY D CA  1 
ATOM 9847  C C   . GLY D 1 155 ? 16.391  -47.100 55.955  1.00 84.22  ? 155 GLY D C   1 
ATOM 9848  O O   . GLY D 1 155 ? 17.550  -46.903 55.532  1.00 97.42  ? 155 GLY D O   1 
ATOM 9849  N N   . GLU D 1 156 ? 15.881  -48.308 56.193  1.00 79.98  ? 156 GLU D N   1 
ATOM 9850  C CA  . GLU D 1 156 ? 16.748  -49.508 56.048  1.00 81.26  ? 156 GLU D CA  1 
ATOM 9851  C C   . GLU D 1 156 ? 16.655  -50.124 54.649  1.00 75.99  ? 156 GLU D C   1 
ATOM 9852  O O   . GLU D 1 156 ? 17.312  -51.162 54.455  1.00 90.22  ? 156 GLU D O   1 
ATOM 9853  C CB  . GLU D 1 156 ? 16.533  -50.495 57.199  1.00 77.52  ? 156 GLU D CB  1 
ATOM 9854  C CG  . GLU D 1 156 ? 17.147  -50.041 58.513  1.00 73.72  ? 156 GLU D CG  1 
ATOM 9855  C CD  . GLU D 1 156 ? 17.299  -51.126 59.564  1.00 89.17  ? 156 GLU D CD  1 
ATOM 9856  O OE1 . GLU D 1 156 ? 16.675  -52.192 59.408  1.00 81.46  ? 156 GLU D OE1 1 
ATOM 9857  O OE2 . GLU D 1 156 ? 18.052  -50.909 60.537  1.00 97.91  ? 156 GLU D OE2 1 
ATOM 9858  N N   . LYS D 1 157 ? 15.811  -49.593 53.764  1.00 61.47  ? 157 LYS D N   1 
ATOM 9859  C CA  . LYS D 1 157 ? 15.718  -50.061 52.350  1.00 79.20  ? 157 LYS D CA  1 
ATOM 9860  C C   . LYS D 1 157 ? 14.895  -51.346 52.312  1.00 77.74  ? 157 LYS D C   1 
ATOM 9861  O O   . LYS D 1 157 ? 15.104  -52.193 53.178  1.00 79.91  ? 157 LYS D O   1 
ATOM 9862  C CB  . LYS D 1 157 ? 17.079  -50.249 51.674  1.00 66.33  ? 157 LYS D CB  1 
ATOM 9863  C CG  . LYS D 1 157 ? 17.037  -50.749 50.238  1.00 81.65  ? 157 LYS D CG  1 
ATOM 9864  C CD  . LYS D 1 157 ? 16.331  -49.809 49.285  1.00 87.30  ? 157 LYS D CD  1 
ATOM 9865  C CE  . LYS D 1 157 ? 16.434  -50.223 47.833  1.00 85.87  ? 157 LYS D CE  1 
ATOM 9866  N NZ  . LYS D 1 157 ? 15.556  -49.401 46.967  1.00 94.77  ? 157 LYS D NZ  1 
ATOM 9867  N N   . TYR D 1 158 ? 14.089  -51.534 51.278  1.00 67.17  ? 158 TYR D N   1 
ATOM 9868  C CA  . TYR D 1 158 ? 13.342  -52.807 51.180  1.00 63.93  ? 158 TYR D CA  1 
ATOM 9869  C C   . TYR D 1 158 ? 14.357  -53.923 50.977  1.00 64.17  ? 158 TYR D C   1 
ATOM 9870  O O   . TYR D 1 158 ? 15.313  -53.732 50.225  1.00 60.96  ? 158 TYR D O   1 
ATOM 9871  C CB  . TYR D 1 158 ? 12.260  -52.733 50.104  1.00 55.16  ? 158 TYR D CB  1 
ATOM 9872  C CG  . TYR D 1 158 ? 11.172  -53.764 50.219  1.00 56.26  ? 158 TYR D CG  1 
ATOM 9873  C CD1 . TYR D 1 158 ? 10.242  -53.709 51.243  1.00 55.43  ? 158 TYR D CD1 1 
ATOM 9874  C CD2 . TYR D 1 158 ? 11.066  -54.790 49.300  1.00 62.03  ? 158 TYR D CD2 1 
ATOM 9875  C CE1 . TYR D 1 158 ? 9.242   -54.656 51.359  1.00 53.64  ? 158 TYR D CE1 1 
ATOM 9876  C CE2 . TYR D 1 158 ? 10.067  -55.738 49.395  1.00 60.62  ? 158 TYR D CE2 1 
ATOM 9877  C CZ  . TYR D 1 158 ? 9.154   -55.674 50.430  1.00 51.41  ? 158 TYR D CZ  1 
ATOM 9878  O OH  . TYR D 1 158 ? 8.172   -56.613 50.521  1.00 54.25  ? 158 TYR D OH  1 
ATOM 9879  N N   . PRO D 1 159 ? 14.146  -55.103 51.583  1.00 67.61  ? 159 PRO D N   1 
ATOM 9880  C CA  . PRO D 1 159 ? 15.105  -56.194 51.504  1.00 63.88  ? 159 PRO D CA  1 
ATOM 9881  C C   . PRO D 1 159 ? 15.344  -56.703 50.080  1.00 60.22  ? 159 PRO D C   1 
ATOM 9882  O O   . PRO D 1 159 ? 16.268  -57.461 49.910  1.00 64.86  ? 159 PRO D O   1 
ATOM 9883  C CB  . PRO D 1 159 ? 14.446  -57.258 52.379  1.00 52.97  ? 159 PRO D CB  1 
ATOM 9884  C CG  . PRO D 1 159 ? 13.674  -56.466 53.383  1.00 52.83  ? 159 PRO D CG  1 
ATOM 9885  C CD  . PRO D 1 159 ? 13.064  -55.386 52.525  1.00 62.45  ? 159 PRO D CD  1 
ATOM 9886  N N   . PHE D 1 160 ? 14.491  -56.319 49.123  1.00 62.26  ? 160 PHE D N   1 
ATOM 9887  C CA  . PHE D 1 160 ? 14.629  -56.787 47.718  1.00 66.20  ? 160 PHE D CA  1 
ATOM 9888  C C   . PHE D 1 160 ? 14.533  -55.637 46.699  1.00 64.84  ? 160 PHE D C   1 
ATOM 9889  O O   . PHE D 1 160 ? 13.368  -55.305 46.430  1.00 47.97  ? 160 PHE D O   1 
ATOM 9890  C CB  . PHE D 1 160 ? 13.483  -57.764 47.467  1.00 55.75  ? 160 PHE D CB  1 
ATOM 9891  C CG  . PHE D 1 160 ? 13.149  -58.616 48.669  1.00 56.28  ? 160 PHE D CG  1 
ATOM 9892  C CD1 . PHE D 1 160 ? 14.033  -59.575 49.132  1.00 60.09  ? 160 PHE D CD1 1 
ATOM 9893  C CD2 . PHE D 1 160 ? 11.964  -58.441 49.358  1.00 56.29  ? 160 PHE D CD2 1 
ATOM 9894  C CE1 . PHE D 1 160 ? 13.745  -60.326 50.258  1.00 53.01  ? 160 PHE D CE1 1 
ATOM 9895  C CE2 . PHE D 1 160 ? 11.667  -59.206 50.476  1.00 59.83  ? 160 PHE D CE2 1 
ATOM 9896  C CZ  . PHE D 1 160 ? 12.560  -60.143 50.928  1.00 54.61  ? 160 PHE D CZ  1 
ATOM 9897  N N   . PRO D 1 161 ? 15.609  -55.033 46.083  1.00 69.95  ? 161 PRO D N   1 
ATOM 9898  C CA  . PRO D 1 161 ? 15.371  -53.981 45.085  1.00 73.10  ? 161 PRO D CA  1 
ATOM 9899  C C   . PRO D 1 161 ? 14.517  -54.472 43.906  1.00 61.57  ? 161 PRO D C   1 
ATOM 9900  O O   . PRO D 1 161 ? 13.691  -53.710 43.439  1.00 69.05  ? 161 PRO D O   1 
ATOM 9901  C CB  . PRO D 1 161 ? 16.777  -53.588 44.612  1.00 79.63  ? 161 PRO D CB  1 
ATOM 9902  C CG  . PRO D 1 161 ? 17.636  -54.793 44.933  1.00 77.48  ? 161 PRO D CG  1 
ATOM 9903  C CD  . PRO D 1 161 ? 17.025  -55.394 46.180  1.00 67.62  ? 161 PRO D CD  1 
ATOM 9904  N N   . ASP D 1 162 ? 14.747  -55.707 43.450  1.00 54.20  ? 162 ASP D N   1 
ATOM 9905  C CA  . ASP D 1 162 ? 14.019  -56.255 42.273  1.00 67.89  ? 162 ASP D CA  1 
ATOM 9906  C C   . ASP D 1 162 ? 12.514  -56.012 42.420  1.00 67.18  ? 162 ASP D C   1 
ATOM 9907  O O   . ASP D 1 162 ? 11.893  -55.586 41.426  1.00 80.12  ? 162 ASP D O   1 
ATOM 9908  C CB  . ASP D 1 162 ? 14.324  -57.742 42.083  1.00 64.29  ? 162 ASP D CB  1 
ATOM 9909  C CG  . ASP D 1 162 ? 15.804  -58.037 41.902  1.00 70.05  ? 162 ASP D CG  1 
ATOM 9910  O OD1 . ASP D 1 162 ? 16.580  -57.074 41.741  1.00 75.31  ? 162 ASP D OD1 1 
ATOM 9911  O OD2 . ASP D 1 162 ? 16.170  -59.228 41.928  1.00 60.42  ? 162 ASP D OD2 1 
ATOM 9912  N N   . PHE D 1 163 ? 11.951  -56.269 43.605  1.00 59.12  ? 163 PHE D N   1 
ATOM 9913  C CA  . PHE D 1 163 ? 10.489  -56.137 43.789  1.00 48.16  ? 163 PHE D CA  1 
ATOM 9914  C C   . PHE D 1 163 ? 10.187  -54.675 44.098  1.00 48.99  ? 163 PHE D C   1 
ATOM 9915  O O   . PHE D 1 163 ? 9.369   -54.069 43.395  1.00 64.52  ? 163 PHE D O   1 
ATOM 9916  C CB  . PHE D 1 163 ? 10.011  -57.043 44.922  1.00 56.54  ? 163 PHE D CB  1 
ATOM 9917  C CG  . PHE D 1 163 ? 8.537   -56.947 45.207  1.00 53.86  ? 163 PHE D CG  1 
ATOM 9918  C CD1 . PHE D 1 163 ? 7.621   -57.550 44.365  1.00 60.75  ? 163 PHE D CD1 1 
ATOM 9919  C CD2 . PHE D 1 163 ? 8.068   -56.238 46.300  1.00 40.56  ? 163 PHE D CD2 1 
ATOM 9920  C CE1 . PHE D 1 163 ? 6.264   -57.449 44.614  1.00 61.36  ? 163 PHE D CE1 1 
ATOM 9921  C CE2 . PHE D 1 163 ? 6.712   -56.130 46.541  1.00 36.45  ? 163 PHE D CE2 1 
ATOM 9922  C CZ  . PHE D 1 163 ? 5.812   -56.734 45.695  1.00 53.32  ? 163 PHE D CZ  1 
ATOM 9923  N N   . TYR D 1 164 ? 10.831  -54.127 45.127  1.00 52.23  ? 164 TYR D N   1 
ATOM 9924  C CA  . TYR D 1 164 ? 10.643  -52.689 45.436  1.00 52.86  ? 164 TYR D CA  1 
ATOM 9925  C C   . TYR D 1 164 ? 11.997  -52.013 45.604  1.00 63.03  ? 164 TYR D C   1 
ATOM 9926  O O   . TYR D 1 164 ? 12.769  -52.416 46.481  1.00 65.03  ? 164 TYR D O   1 
ATOM 9927  C CB  . TYR D 1 164 ? 9.804   -52.489 46.695  1.00 53.86  ? 164 TYR D CB  1 
ATOM 9928  C CG  . TYR D 1 164 ? 9.602   -51.052 47.100  1.00 60.09  ? 164 TYR D CG  1 
ATOM 9929  C CD1 . TYR D 1 164 ? 9.075   -50.130 46.216  1.00 62.09  ? 164 TYR D CD1 1 
ATOM 9930  C CD2 . TYR D 1 164 ? 9.938   -50.616 48.369  1.00 62.27  ? 164 TYR D CD2 1 
ATOM 9931  C CE1 . TYR D 1 164 ? 8.891   -48.809 46.577  1.00 64.15  ? 164 TYR D CE1 1 
ATOM 9932  C CE2 . TYR D 1 164 ? 9.756   -49.299 48.750  1.00 68.35  ? 164 TYR D CE2 1 
ATOM 9933  C CZ  . TYR D 1 164 ? 9.233   -48.390 47.851  1.00 76.75  ? 164 TYR D CZ  1 
ATOM 9934  O OH  . TYR D 1 164 ? 9.050   -47.090 48.213  1.00 78.23  ? 164 TYR D OH  1 
ATOM 9935  N N   . ASP D 1 165 ? 12.257  -51.000 44.785  1.00 63.87  ? 165 ASP D N   1 
ATOM 9936  C CA  . ASP D 1 165 ? 13.520  -50.245 44.939  1.00 65.92  ? 165 ASP D CA  1 
ATOM 9937  C C   . ASP D 1 165 ? 13.206  -48.954 45.689  1.00 73.05  ? 165 ASP D C   1 
ATOM 9938  O O   . ASP D 1 165 ? 12.777  -47.984 45.045  1.00 71.62  ? 165 ASP D O   1 
ATOM 9939  C CB  . ASP D 1 165 ? 14.185  -49.986 43.591  1.00 70.88  ? 165 ASP D CB  1 
ATOM 9940  C CG  . ASP D 1 165 ? 15.586  -49.410 43.708  1.00 81.62  ? 165 ASP D CG  1 
ATOM 9941  O OD1 . ASP D 1 165 ? 16.027  -49.167 44.845  1.00 83.08  ? 165 ASP D OD1 1 
ATOM 9942  O OD2 . ASP D 1 165 ? 16.233  -49.219 42.659  1.00 87.51  ? 165 ASP D OD2 1 
ATOM 9943  N N   . ASN D 1 166 ? 13.433  -48.957 47.001  1.00 81.49  ? 166 ASN D N   1 
ATOM 9944  C CA  . ASN D 1 166 ? 13.136  -47.772 47.839  1.00 78.14  ? 166 ASN D CA  1 
ATOM 9945  C C   . ASN D 1 166 ? 13.914  -46.564 47.323  1.00 91.20  ? 166 ASN D C   1 
ATOM 9946  O O   . ASN D 1 166 ? 13.273  -45.527 47.092  1.00 99.42  ? 166 ASN D O   1 
ATOM 9947  C CB  . ASN D 1 166 ? 13.456  -48.050 49.311  1.00 81.26  ? 166 ASN D CB  1 
ATOM 9948  C CG  . ASN D 1 166 ? 13.198  -46.863 50.212  1.00 94.98  ? 166 ASN D CG  1 
ATOM 9949  O OD1 . ASN D 1 166 ? 14.116  -46.338 50.838  1.00 100.05 ? 166 ASN D OD1 1 
ATOM 9950  N ND2 . ASN D 1 166 ? 11.952  -46.425 50.279  1.00 97.73  ? 166 ASN D ND2 1 
ATOM 9951  N N   . SER D 1 167 ? 15.233  -46.698 47.124  1.00 93.65  ? 167 SER D N   1 
ATOM 9952  C CA  . SER D 1 167 ? 16.048  -45.507 46.763  1.00 92.31  ? 167 SER D CA  1 
ATOM 9953  C C   . SER D 1 167 ? 15.221  -44.538 45.913  1.00 96.44  ? 167 SER D C   1 
ATOM 9954  O O   . SER D 1 167 ? 15.398  -43.320 46.104  1.00 98.51  ? 167 SER D O   1 
ATOM 9955  C CB  . SER D 1 167 ? 17.307  -45.912 46.049  1.00 85.67  ? 167 SER D CB  1 
ATOM 9956  O OG  . SER D 1 167 ? 18.173  -44.799 45.892  1.00 92.23  ? 167 SER D OG  1 
ATOM 9957  N N   . ASN D 1 178 ? -1.312  -37.561 55.899  1.00 131.88 ? 178 ASN D N   1 
ATOM 9958  C CA  . ASN D 1 178 ? 0.121   -37.479 56.145  1.00 134.90 ? 178 ASN D CA  1 
ATOM 9959  C C   . ASN D 1 178 ? 0.512   -38.298 57.369  1.00 130.80 ? 178 ASN D C   1 
ATOM 9960  O O   . ASN D 1 178 ? 1.676   -38.659 57.547  1.00 125.70 ? 178 ASN D O   1 
ATOM 9961  C CB  . ASN D 1 178 ? 0.552   -36.024 56.328  1.00 133.80 ? 178 ASN D CB  1 
ATOM 9962  C CG  . ASN D 1 178 ? -0.199  -35.327 57.448  1.00 135.90 ? 178 ASN D CG  1 
ATOM 9963  O OD1 . ASN D 1 178 ? 0.226   -35.345 58.601  1.00 141.19 ? 178 ASN D OD1 1 
ATOM 9964  N ND2 . ASN D 1 178 ? -1.324  -34.709 57.107  1.00 128.30 ? 178 ASN D ND2 1 
ATOM 9965  N N   . MET D 1 179 ? -0.474  -38.594 58.216  1.00 133.40 ? 179 MET D N   1 
ATOM 9966  C CA  . MET D 1 179 ? -0.232  -39.345 59.440  1.00 129.45 ? 179 MET D CA  1 
ATOM 9967  C C   . MET D 1 179 ? -1.472  -40.120 59.861  1.00 125.34 ? 179 MET D C   1 
ATOM 9968  O O   . MET D 1 179 ? -1.372  -41.247 60.361  1.00 120.30 ? 179 MET D O   1 
ATOM 9969  C CB  . MET D 1 179 ? 0.212   -38.395 60.558  1.00 128.00 ? 179 MET D CB  1 
ATOM 9970  C CG  . MET D 1 179 ? 0.140   -38.975 61.971  1.00 132.53 ? 179 MET D CG  1 
ATOM 9971  S SD  . MET D 1 179 ? 1.085   -40.496 62.204  1.00 158.05 ? 179 MET D SD  1 
ATOM 9972  C CE  . MET D 1 179 ? 2.746   -39.938 61.837  1.00 136.35 ? 179 MET D CE  1 
ATOM 9973  N N   . LYS D 1 180 ? -2.646  -39.532 59.646  1.00 126.71 ? 180 LYS D N   1 
ATOM 9974  C CA  . LYS D 1 180 ? -3.887  -40.040 60.223  1.00 122.73 ? 180 LYS D CA  1 
ATOM 9975  C C   . LYS D 1 180 ? -4.360  -41.294 59.491  1.00 120.05 ? 180 LYS D C   1 
ATOM 9976  O O   . LYS D 1 180 ? -5.421  -41.849 59.795  1.00 113.84 ? 180 LYS D O   1 
ATOM 9977  C CB  . LYS D 1 180 ? -4.973  -38.961 60.192  1.00 121.01 ? 180 LYS D CB  1 
ATOM 9978  C CG  . LYS D 1 180 ? -4.540  -37.620 60.740  1.00 124.42 ? 180 LYS D CG  1 
ATOM 9979  C CD  . LYS D 1 180 ? -5.621  -36.571 60.528  1.00 120.59 ? 180 LYS D CD  1 
ATOM 9980  C CE  . LYS D 1 180 ? -5.091  -35.173 60.792  1.00 130.74 ? 180 LYS D CE  1 
ATOM 9981  N NZ  . LYS D 1 180 ? -3.943  -34.828 59.913  1.00 126.68 ? 180 LYS D NZ  1 
ATOM 9982  N N   . LEU D 1 181 ? -3.573  -41.739 58.520  1.00 117.29 ? 181 LEU D N   1 
ATOM 9983  C CA  . LEU D 1 181 ? -3.836  -42.962 57.782  1.00 111.04 ? 181 LEU D CA  1 
ATOM 9984  C C   . LEU D 1 181 ? -2.745  -44.014 57.941  1.00 105.76 ? 181 LEU D C   1 
ATOM 9985  O O   . LEU D 1 181 ? -3.054  -45.212 57.942  1.00 101.29 ? 181 LEU D O   1 
ATOM 9986  C CB  . LEU D 1 181 ? -4.030  -42.643 56.288  1.00 105.63 ? 181 LEU D CB  1 
ATOM 9987  C CG  . LEU D 1 181 ? -4.819  -43.658 55.459  1.00 109.57 ? 181 LEU D CG  1 
ATOM 9988  C CD1 . LEU D 1 181 ? -5.576  -42.954 54.344  1.00 115.86 ? 181 LEU D CD1 1 
ATOM 9989  C CD2 . LEU D 1 181 ? -3.889  -44.711 54.890  1.00 108.34 ? 181 LEU D CD2 1 
ATOM 9990  N N   . LEU D 1 182 ? -1.481  -43.602 58.072  1.00 96.82  ? 182 LEU D N   1 
ATOM 9991  C CA  . LEU D 1 182 ? -0.401  -44.561 58.274  1.00 90.50  ? 182 LEU D CA  1 
ATOM 9992  C C   . LEU D 1 182 ? -0.582  -45.318 59.583  1.00 89.83  ? 182 LEU D C   1 
ATOM 9993  O O   . LEU D 1 182 ? -0.409  -46.544 59.635  1.00 86.53  ? 182 LEU D O   1 
ATOM 9994  C CB  . LEU D 1 182 ? 0.946   -43.836 58.247  1.00 90.89  ? 182 LEU D CB  1 
ATOM 9995  C CG  . LEU D 1 182 ? 2.225   -44.591 58.613  1.00 82.97  ? 182 LEU D CG  1 
ATOM 9996  C CD1 . LEU D 1 182 ? 2.553   -45.677 57.594  1.00 82.08  ? 182 LEU D CD1 1 
ATOM 9997  C CD2 . LEU D 1 182 ? 3.382   -43.612 58.738  1.00 92.19  ? 182 LEU D CD2 1 
ATOM 9998  N N   . HIS D 1 183 ? -0.935  -44.601 60.652  1.00 94.36  ? 183 HIS D N   1 
ATOM 9999  C CA  . HIS D 1 183 ? -1.194  -45.256 61.928  1.00 94.96  ? 183 HIS D CA  1 
ATOM 10000 C C   . HIS D 1 183 ? -2.379  -46.208 61.830  1.00 89.38  ? 183 HIS D C   1 
ATOM 10001 O O   . HIS D 1 183 ? -2.369  -47.286 62.432  1.00 85.40  ? 183 HIS D O   1 
ATOM 10002 C CB  . HIS D 1 183 ? -1.436  -44.215 63.017  1.00 95.69  ? 183 HIS D CB  1 
ATOM 10003 C CG  . HIS D 1 183 ? -1.854  -44.809 64.327  1.00 100.91 ? 183 HIS D CG  1 
ATOM 10004 N ND1 . HIS D 1 183 ? -1.279  -45.947 64.842  1.00 100.65 ? 183 HIS D ND1 1 
ATOM 10005 C CD2 . HIS D 1 183 ? -2.798  -44.425 65.220  1.00 97.58  ? 183 HIS D CD2 1 
ATOM 10006 C CE1 . HIS D 1 183 ? -1.843  -46.239 66.001  1.00 97.27  ? 183 HIS D CE1 1 
ATOM 10007 N NE2 . HIS D 1 183 ? -2.770  -45.332 66.252  1.00 89.81  ? 183 HIS D NE2 1 
ATOM 10008 N N   . ASP D 1 184 ? -3.328  -45.873 60.969  1.00 88.46  ? 184 ASP D N   1 
ATOM 10009 C CA  . ASP D 1 184 ? -4.540  -46.718 60.899  1.00 89.83  ? 184 ASP D CA  1 
ATOM 10010 C C   . ASP D 1 184 ? -4.250  -47.957 60.046  1.00 84.30  ? 184 ASP D C   1 
ATOM 10011 O O   . ASP D 1 184 ? -5.069  -48.874 60.075  1.00 86.31  ? 184 ASP D O   1 
ATOM 10012 C CB  . ASP D 1 184 ? -5.745  -45.893 60.460  1.00 99.82  ? 184 ASP D CB  1 
ATOM 10013 C CG  . ASP D 1 184 ? -5.957  -44.678 61.338  1.00 103.40 ? 184 ASP D CG  1 
ATOM 10014 O OD1 . ASP D 1 184 ? -5.014  -43.878 61.452  1.00 109.97 ? 184 ASP D OD1 1 
ATOM 10015 O OD2 . ASP D 1 184 ? -7.055  -44.549 61.905  1.00 88.31  ? 184 ASP D OD2 1 
ATOM 10016 N N   . PHE D 1 185 ? -3.117  -47.994 59.358  1.00 74.87  ? 185 PHE D N   1 
ATOM 10017 C CA  . PHE D 1 185 ? -2.729  -49.190 58.578  1.00 71.51  ? 185 PHE D CA  1 
ATOM 10018 C C   . PHE D 1 185 ? -2.001  -50.170 59.487  1.00 68.45  ? 185 PHE D C   1 
ATOM 10019 O O   . PHE D 1 185 ? -2.221  -51.369 59.387  1.00 60.68  ? 185 PHE D O   1 
ATOM 10020 C CB  . PHE D 1 185 ? -1.844  -48.748 57.416  1.00 68.06  ? 185 PHE D CB  1 
ATOM 10021 C CG  . PHE D 1 185 ? -0.961  -49.800 56.797  1.00 67.26  ? 185 PHE D CG  1 
ATOM 10022 C CD1 . PHE D 1 185 ? 0.259   -50.130 57.357  1.00 68.15  ? 185 PHE D CD1 1 
ATOM 10023 C CD2 . PHE D 1 185 ? -1.315  -50.410 55.606  1.00 72.03  ? 185 PHE D CD2 1 
ATOM 10024 C CE1 . PHE D 1 185 ? 1.078   -51.077 56.769  1.00 69.62  ? 185 PHE D CE1 1 
ATOM 10025 C CE2 . PHE D 1 185 ? -0.496  -51.361 55.021  1.00 70.79  ? 185 PHE D CE2 1 
ATOM 10026 C CZ  . PHE D 1 185 ? 0.698   -51.693 55.603  1.00 69.25  ? 185 PHE D CZ  1 
ATOM 10027 N N   . ILE D 1 186 ? -1.160  -49.654 60.362  1.00 68.46  ? 186 ILE D N   1 
ATOM 10028 C CA  . ILE D 1 186 ? -0.311  -50.511 61.229  1.00 66.27  ? 186 ILE D CA  1 
ATOM 10029 C C   . ILE D 1 186 ? -1.182  -51.038 62.355  1.00 56.23  ? 186 ILE D C   1 
ATOM 10030 O O   . ILE D 1 186 ? -0.930  -52.141 62.865  1.00 49.81  ? 186 ILE D O   1 
ATOM 10031 C CB  . ILE D 1 186 ? 0.850   -49.651 61.763  1.00 69.84  ? 186 ILE D CB  1 
ATOM 10032 C CG1 . ILE D 1 186 ? 1.631   -48.991 60.626  1.00 72.74  ? 186 ILE D CG1 1 
ATOM 10033 C CG2 . ILE D 1 186 ? 1.755   -50.462 62.674  1.00 63.73  ? 186 ILE D CG2 1 
ATOM 10034 C CD1 . ILE D 1 186 ? 1.892   -47.532 60.863  1.00 79.14  ? 186 ILE D CD1 1 
ATOM 10035 N N   . ALA D 1 187 ? -2.178  -50.245 62.706  1.00 65.10  ? 187 ALA D N   1 
ATOM 10036 C CA  . ALA D 1 187 ? -3.076  -50.631 63.811  1.00 61.27  ? 187 ALA D CA  1 
ATOM 10037 C C   . ALA D 1 187 ? -3.506  -52.078 63.646  1.00 56.41  ? 187 ALA D C   1 
ATOM 10038 O O   . ALA D 1 187 ? -3.292  -52.867 64.559  1.00 50.54  ? 187 ALA D O   1 
ATOM 10039 C CB  . ALA D 1 187 ? -4.270  -49.732 63.786  1.00 71.45  ? 187 ALA D CB  1 
ATOM 10040 N N   . CYS D 1 188 ? -4.101  -52.385 62.506  1.00 60.83  ? 188 CYS D N   1 
ATOM 10041 C CA  . CYS D 1 188 ? -4.625  -53.742 62.387  1.00 58.69  ? 188 CYS D CA  1 
ATOM 10042 C C   . CYS D 1 188 ? -3.529  -54.789 62.524  1.00 56.79  ? 188 CYS D C   1 
ATOM 10043 O O   . CYS D 1 188 ? -3.814  -55.938 62.884  1.00 59.79  ? 188 CYS D O   1 
ATOM 10044 C CB  . CYS D 1 188 ? -5.365  -53.904 61.061  1.00 48.35  ? 188 CYS D CB  1 
ATOM 10045 S SG  . CYS D 1 188 ? -4.619  -53.008 59.690  1.00 64.10  ? 188 CYS D SG  1 
ATOM 10046 N N   . PHE D 1 189 ? -2.277  -54.426 62.239  1.00 52.49  ? 189 PHE D N   1 
ATOM 10047 C CA  . PHE D 1 189 ? -1.175  -55.352 62.477  1.00 42.99  ? 189 PHE D CA  1 
ATOM 10048 C C   . PHE D 1 189 ? -0.754  -55.346 63.941  1.00 48.32  ? 189 PHE D C   1 
ATOM 10049 O O   . PHE D 1 189 ? -0.464  -56.405 64.511  1.00 46.25  ? 189 PHE D O   1 
ATOM 10050 C CB  . PHE D 1 189 ? 0.017   -55.002 61.587  1.00 44.88  ? 189 PHE D CB  1 
ATOM 10051 C CG  . PHE D 1 189 ? -0.263  -55.143 60.122  1.00 51.05  ? 189 PHE D CG  1 
ATOM 10052 C CD1 . PHE D 1 189 ? -0.108  -56.364 59.489  1.00 47.58  ? 189 PHE D CD1 1 
ATOM 10053 C CD2 . PHE D 1 189 ? -0.681  -54.055 59.374  1.00 49.00  ? 189 PHE D CD2 1 
ATOM 10054 C CE1 . PHE D 1 189 ? -0.364  -56.498 58.137  1.00 39.92  ? 189 PHE D CE1 1 
ATOM 10055 C CE2 . PHE D 1 189 ? -0.941  -54.181 58.026  1.00 48.85  ? 189 PHE D CE2 1 
ATOM 10056 C CZ  . PHE D 1 189 ? -0.783  -55.405 57.406  1.00 49.15  ? 189 PHE D CZ  1 
ATOM 10057 N N   . GLU D 1 190 ? -0.719  -54.165 64.561  1.00 53.88  ? 190 GLU D N   1 
ATOM 10058 C CA  . GLU D 1 190 ? -0.296  -54.062 65.954  1.00 54.40  ? 190 GLU D CA  1 
ATOM 10059 C C   . GLU D 1 190 ? -1.328  -54.677 66.894  1.00 51.41  ? 190 GLU D C   1 
ATOM 10060 O O   . GLU D 1 190 ? -0.987  -55.492 67.757  1.00 42.93  ? 190 GLU D O   1 
ATOM 10061 C CB  . GLU D 1 190 ? -0.049  -52.598 66.317  1.00 58.34  ? 190 GLU D CB  1 
ATOM 10062 C CG  . GLU D 1 190 ? 0.168   -52.354 67.801  1.00 78.00  ? 190 GLU D CG  1 
ATOM 10063 C CD  . GLU D 1 190 ? -0.240  -50.953 68.228  1.00 89.12  ? 190 GLU D CD  1 
ATOM 10064 O OE1 . GLU D 1 190 ? -0.784  -50.205 67.388  1.00 91.83  ? 190 GLU D OE1 1 
ATOM 10065 O OE2 . GLU D 1 190 ? -0.022  -50.604 69.407  1.00 73.69  ? 190 GLU D OE2 1 
ATOM 10066 N N   . ARG D 1 191 ? -2.598  -54.295 66.740  1.00 58.23  ? 191 ARG D N   1 
ATOM 10067 C CA  . ARG D 1 191 ? -3.632  -54.749 67.662  1.00 52.44  ? 191 ARG D CA  1 
ATOM 10068 C C   . ARG D 1 191 ? -4.026  -56.205 67.453  1.00 47.60  ? 191 ARG D C   1 
ATOM 10069 O O   . ARG D 1 191 ? -4.835  -56.725 68.231  1.00 60.23  ? 191 ARG D O   1 
ATOM 10070 C CB  . ARG D 1 191 ? -4.870  -53.857 67.543  1.00 59.71  ? 191 ARG D CB  1 
ATOM 10071 C CG  . ARG D 1 191 ? -4.784  -52.594 68.377  1.00 58.86  ? 191 ARG D CG  1 
ATOM 10072 C CD  . ARG D 1 191 ? -4.765  -52.929 69.864  1.00 61.49  ? 191 ARG D CD  1 
ATOM 10073 N NE  . ARG D 1 191 ? -4.489  -51.762 70.693  1.00 70.43  ? 191 ARG D NE  1 
ATOM 10074 C CZ  . ARG D 1 191 ? -5.416  -50.929 71.151  1.00 78.71  ? 191 ARG D CZ  1 
ATOM 10075 N NH1 . ARG D 1 191 ? -6.698  -51.096 70.864  1.00 75.98  ? 191 ARG D NH1 1 
ATOM 10076 N NH2 . ARG D 1 191 ? -5.049  -49.906 71.917  1.00 85.28  ? 191 ARG D NH2 1 
ATOM 10077 N N   . SER D 1 192 ? -3.487  -56.874 66.437  1.00 43.87  ? 192 SER D N   1 
ATOM 10078 C CA  . SER D 1 192 ? -3.804  -58.280 66.227  1.00 44.19  ? 192 SER D CA  1 
ATOM 10079 C C   . SER D 1 192 ? -3.175  -59.126 67.328  1.00 43.76  ? 192 SER D C   1 
ATOM 10080 O O   . SER D 1 192 ? -1.992  -58.972 67.643  1.00 54.11  ? 192 SER D O   1 
ATOM 10081 C CB  . SER D 1 192 ? -3.315  -58.733 64.854  1.00 37.28  ? 192 SER D CB  1 
ATOM 10082 O OG  . SER D 1 192 ? -3.696  -60.073 64.597  1.00 41.82  ? 192 SER D OG  1 
ATOM 10083 N N   . CYS D 1 193 ? -3.968  -60.017 67.916  1.00 41.84  ? 193 CYS D N   1 
ATOM 10084 C CA  . CYS D 1 193 ? -3.516  -60.816 69.049  1.00 43.33  ? 193 CYS D CA  1 
ATOM 10085 C C   . CYS D 1 193 ? -2.685  -61.991 68.543  1.00 51.50  ? 193 CYS D C   1 
ATOM 10086 O O   . CYS D 1 193 ? -3.202  -62.877 67.856  1.00 47.13  ? 193 CYS D O   1 
ATOM 10087 C CB  . CYS D 1 193 ? -4.710  -61.299 69.871  1.00 47.96  ? 193 CYS D CB  1 
ATOM 10088 S SG  . CYS D 1 193 ? -4.279  -62.146 71.411  1.00 83.54  ? 193 CYS D SG  1 
ATOM 10089 N N   . ASP D 1 194 ? -1.388  -61.977 68.867  1.00 56.80  ? 194 ASP D N   1 
ATOM 10090 C CA  . ASP D 1 194 ? -0.458  -63.075 68.611  1.00 55.57  ? 194 ASP D CA  1 
ATOM 10091 C C   . ASP D 1 194 ? -0.222  -63.343 67.125  1.00 58.56  ? 194 ASP D C   1 
ATOM 10092 O O   . ASP D 1 194 ? 0.920   -63.268 66.658  1.00 59.33  ? 194 ASP D O   1 
ATOM 10093 C CB  . ASP D 1 194 ? -0.939  -64.353 69.298  1.00 61.90  ? 194 ASP D CB  1 
ATOM 10094 C CG  . ASP D 1 194 ? -1.013  -64.209 70.802  1.00 75.16  ? 194 ASP D CG  1 
ATOM 10095 O OD1 . ASP D 1 194 ? -0.140  -63.532 71.381  1.00 85.48  ? 194 ASP D OD1 1 
ATOM 10096 O OD2 . ASP D 1 194 ? -1.947  -64.776 71.407  1.00 64.57  ? 194 ASP D OD2 1 
ATOM 10097 N N   . ILE D 1 195 ? -1.273  -63.673 66.375  1.00 53.70  ? 195 ILE D N   1 
ATOM 10098 C CA  . ILE D 1 195 ? -1.132  -64.095 64.990  1.00 53.76  ? 195 ILE D CA  1 
ATOM 10099 C C   . ILE D 1 195 ? -1.846  -63.106 64.078  1.00 45.66  ? 195 ILE D C   1 
ATOM 10100 O O   . ILE D 1 195 ? -2.539  -62.195 64.524  1.00 44.49  ? 195 ILE D O   1 
ATOM 10101 C CB  . ILE D 1 195 ? -1.660  -65.526 64.756  1.00 59.08  ? 195 ILE D CB  1 
ATOM 10102 C CG1 . ILE D 1 195 ? -3.187  -65.552 64.834  1.00 49.08  ? 195 ILE D CG1 1 
ATOM 10103 C CG2 . ILE D 1 195 ? -1.044  -66.496 65.755  1.00 53.07  ? 195 ILE D CG2 1 
ATOM 10104 C CD1 . ILE D 1 195 ? -3.800  -66.871 64.409  1.00 34.84  ? 195 ILE D CD1 1 
ATOM 10105 N N   . ILE D 1 196 ? -1.649  -63.300 62.774  1.00 40.67  ? 196 ILE D N   1 
ATOM 10106 C CA  . ILE D 1 196 ? -2.357  -62.564 61.732  1.00 42.86  ? 196 ILE D CA  1 
ATOM 10107 C C   . ILE D 1 196 ? -2.683  -63.546 60.617  1.00 46.08  ? 196 ILE D C   1 
ATOM 10108 O O   . ILE D 1 196 ? -1.772  -64.108 60.000  1.00 43.20  ? 196 ILE D O   1 
ATOM 10109 C CB  . ILE D 1 196 ? -1.545  -61.383 61.172  1.00 45.09  ? 196 ILE D CB  1 
ATOM 10110 C CG1 . ILE D 1 196 ? -1.385  -60.289 62.225  1.00 47.28  ? 196 ILE D CG1 1 
ATOM 10111 C CG2 . ILE D 1 196 ? -2.216  -60.829 59.926  1.00 38.55  ? 196 ILE D CG2 1 
ATOM 10112 C CD1 . ILE D 1 196 ? -0.708  -59.044 61.708  1.00 46.39  ? 196 ILE D CD1 1 
ATOM 10113 N N   . LEU D 1 197 ? -3.968  -63.765 60.365  1.00 39.51  ? 197 LEU D N   1 
ATOM 10114 C CA  . LEU D 1 197 ? -4.389  -64.629 59.275  1.00 45.24  ? 197 LEU D CA  1 
ATOM 10115 C C   . LEU D 1 197 ? -4.253  -63.898 57.945  1.00 40.55  ? 197 LEU D C   1 
ATOM 10116 O O   . LEU D 1 197 ? -4.544  -62.704 57.845  1.00 41.65  ? 197 LEU D O   1 
ATOM 10117 C CB  . LEU D 1 197 ? -5.835  -65.083 59.480  1.00 47.38  ? 197 LEU D CB  1 
ATOM 10118 C CG  . LEU D 1 197 ? -6.105  -66.002 60.672  1.00 45.59  ? 197 LEU D CG  1 
ATOM 10119 C CD1 . LEU D 1 197 ? -7.593  -66.269 60.809  1.00 56.17  ? 197 LEU D CD1 1 
ATOM 10120 C CD2 . LEU D 1 197 ? -5.343  -67.303 60.506  1.00 47.47  ? 197 LEU D CD2 1 
ATOM 10121 N N   . ILE D 1 198 ? -3.805  -64.620 56.920  1.00 33.95  ? 198 ILE D N   1 
ATOM 10122 C CA  . ILE D 1 198 ? -3.592  -64.022 55.607  1.00 39.65  ? 198 ILE D CA  1 
ATOM 10123 C C   . ILE D 1 198 ? -4.117  -64.960 54.528  1.00 35.58  ? 198 ILE D C   1 
ATOM 10124 O O   . ILE D 1 198 ? -3.897  -66.173 54.580  1.00 33.75  ? 198 ILE D O   1 
ATOM 10125 C CB  . ILE D 1 198 ? -2.105  -63.677 55.368  1.00 40.54  ? 198 ILE D CB  1 
ATOM 10126 C CG1 . ILE D 1 198 ? -1.905  -63.117 53.956  1.00 41.12  ? 198 ILE D CG1 1 
ATOM 10127 C CG2 . ILE D 1 198 ? -1.217  -64.882 55.620  1.00 34.83  ? 198 ILE D CG2 1 
ATOM 10128 C CD1 . ILE D 1 198 ? -0.471  -62.761 53.631  1.00 39.00  ? 198 ILE D CD1 1 
ATOM 10129 N N   . LYS D 1 199 ? -4.832  -64.386 53.557  1.00 42.68  ? 199 LYS D N   1 
ATOM 10130 C CA  . LYS D 1 199 ? -5.290  -65.107 52.369  1.00 50.18  ? 199 LYS D CA  1 
ATOM 10131 C C   . LYS D 1 199 ? -4.131  -65.174 51.383  1.00 45.89  ? 199 LYS D C   1 
ATOM 10132 O O   . LYS D 1 199 ? -4.032  -64.409 50.418  1.00 45.64  ? 199 LYS D O   1 
ATOM 10133 C CB  . LYS D 1 199 ? -6.510  -64.429 51.757  1.00 47.82  ? 199 LYS D CB  1 
ATOM 10134 C CG  . LYS D 1 199 ? -7.062  -65.131 50.527  1.00 46.46  ? 199 LYS D CG  1 
ATOM 10135 C CD  . LYS D 1 199 ? -8.121  -64.285 49.838  1.00 45.05  ? 199 LYS D CD  1 
ATOM 10136 C CE  . LYS D 1 199 ? -8.579  -64.919 48.533  1.00 49.06  ? 199 LYS D CE  1 
ATOM 10137 N NZ  . LYS D 1 199 ? -9.531  -64.035 47.811  1.00 54.00  ? 199 LYS D NZ  1 
ATOM 10138 N N   . SER D 1 200 ? -3.226  -66.109 51.642  1.00 40.84  ? 200 SER D N   1 
ATOM 10139 C CA  . SER D 1 200 ? -2.062  -66.314 50.792  1.00 45.13  ? 200 SER D CA  1 
ATOM 10140 C C   . SER D 1 200 ? -1.515  -67.702 51.084  1.00 44.40  ? 200 SER D C   1 
ATOM 10141 O O   . SER D 1 200 ? -2.029  -68.426 51.940  1.00 48.84  ? 200 SER D O   1 
ATOM 10142 C CB  . SER D 1 200 ? -1.012  -65.222 51.022  1.00 41.58  ? 200 SER D CB  1 
ATOM 10143 O OG  . SER D 1 200 ? 0.076   -65.356 50.123  1.00 52.33  ? 200 SER D OG  1 
ATOM 10144 N N   . PHE D 1 201 ? -0.467  -68.076 50.358  1.00 45.49  ? 201 PHE D N   1 
ATOM 10145 C CA  . PHE D 1 201 ? 0.146   -69.385 50.517  1.00 50.38  ? 201 PHE D CA  1 
ATOM 10146 C C   . PHE D 1 201 ? 1.650   -69.254 50.338  1.00 55.10  ? 201 PHE D C   1 
ATOM 10147 O O   . PHE D 1 201 ? 2.130   -68.403 49.583  1.00 53.22  ? 201 PHE D O   1 
ATOM 10148 C CB  . PHE D 1 201 ? -0.434  -70.414 49.533  1.00 54.75  ? 201 PHE D CB  1 
ATOM 10149 C CG  . PHE D 1 201 ? -0.868  -69.832 48.214  1.00 60.92  ? 201 PHE D CG  1 
ATOM 10150 C CD1 . PHE D 1 201 ? -2.122  -69.254 48.077  1.00 59.20  ? 201 PHE D CD1 1 
ATOM 10151 C CD2 . PHE D 1 201 ? -0.036  -69.881 47.112  1.00 58.44  ? 201 PHE D CD2 1 
ATOM 10152 C CE1 . PHE D 1 201 ? -2.527  -68.720 46.867  1.00 56.99  ? 201 PHE D CE1 1 
ATOM 10153 C CE2 . PHE D 1 201 ? -0.440  -69.355 45.897  1.00 61.90  ? 201 PHE D CE2 1 
ATOM 10154 C CZ  . PHE D 1 201 ? -1.685  -68.770 45.778  1.00 61.79  ? 201 PHE D CZ  1 
ATOM 10155 N N   . ARG D 1 202 ? 2.389   -70.108 51.051  1.00 62.47  ? 202 ARG D N   1 
ATOM 10156 C CA  . ARG D 1 202 ? 3.842   -69.994 51.081  1.00 61.61  ? 202 ARG D CA  1 
ATOM 10157 C C   . ARG D 1 202 ? 4.456   -70.215 49.705  1.00 55.39  ? 202 ARG D C   1 
ATOM 10158 O O   . ARG D 1 202 ? 5.471   -69.591 49.376  1.00 53.98  ? 202 ARG D O   1 
ATOM 10159 C CB  . ARG D 1 202 ? 4.419   -70.981 52.096  1.00 55.69  ? 202 ARG D CB  1 
ATOM 10160 C CG  . ARG D 1 202 ? 5.814   -70.642 52.591  1.00 60.84  ? 202 ARG D CG  1 
ATOM 10161 C CD  . ARG D 1 202 ? 5.919   -70.864 54.091  1.00 63.91  ? 202 ARG D CD  1 
ATOM 10162 N NE  . ARG D 1 202 ? 5.099   -69.919 54.839  1.00 81.17  ? 202 ARG D NE  1 
ATOM 10163 C CZ  . ARG D 1 202 ? 4.798   -70.039 56.128  1.00 88.66  ? 202 ARG D CZ  1 
ATOM 10164 N NH1 . ARG D 1 202 ? 5.217   -71.074 56.841  1.00 95.20  ? 202 ARG D NH1 1 
ATOM 10165 N NH2 . ARG D 1 202 ? 4.059   -69.102 56.712  1.00 78.67  ? 202 ARG D NH2 1 
ATOM 10166 N N   . GLU D 1 203 ? 3.847   -71.071 48.881  1.00 49.97  ? 203 GLU D N   1 
ATOM 10167 C CA  . GLU D 1 203 ? 4.413   -71.398 47.577  1.00 57.97  ? 203 GLU D CA  1 
ATOM 10168 C C   . GLU D 1 203 ? 4.511   -70.188 46.655  1.00 55.50  ? 203 GLU D C   1 
ATOM 10169 O O   . GLU D 1 203 ? 5.253   -70.238 45.670  1.00 60.86  ? 203 GLU D O   1 
ATOM 10170 C CB  . GLU D 1 203 ? 3.575   -72.484 46.903  1.00 71.26  ? 203 GLU D CB  1 
ATOM 10171 C CG  . GLU D 1 203 ? 3.162   -73.604 47.837  1.00 79.27  ? 203 GLU D CG  1 
ATOM 10172 C CD  . GLU D 1 203 ? 4.354   -74.354 48.402  1.00 87.02  ? 203 GLU D CD  1 
ATOM 10173 O OE1 . GLU D 1 203 ? 5.334   -74.565 47.654  1.00 92.69  ? 203 GLU D OE1 1 
ATOM 10174 O OE2 . GLU D 1 203 ? 4.309   -74.727 49.594  1.00 80.60  ? 203 GLU D OE2 1 
ATOM 10175 N N   . LEU D 1 204 ? 3.780   -69.113 46.942  1.00 55.75  ? 204 LEU D N   1 
ATOM 10176 C CA  . LEU D 1 204 ? 3.799   -67.923 46.098  1.00 61.37  ? 204 LEU D CA  1 
ATOM 10177 C C   . LEU D 1 204 ? 4.624   -66.784 46.678  1.00 55.47  ? 204 LEU D C   1 
ATOM 10178 O O   . LEU D 1 204 ? 5.264   -66.049 45.919  1.00 62.47  ? 204 LEU D O   1 
ATOM 10179 C CB  . LEU D 1 204 ? 2.370   -67.431 45.843  1.00 61.44  ? 204 LEU D CB  1 
ATOM 10180 C CG  . LEU D 1 204 ? 2.186   -66.195 44.958  1.00 63.46  ? 204 LEU D CG  1 
ATOM 10181 C CD1 . LEU D 1 204 ? 2.905   -66.355 43.627  1.00 62.50  ? 204 LEU D CD1 1 
ATOM 10182 C CD2 . LEU D 1 204 ? 0.704   -65.915 44.735  1.00 64.62  ? 204 LEU D CD2 1 
ATOM 10183 N N   . GLU D 1 205 ? 4.640   -66.620 47.997  1.00 50.25  ? 205 GLU D N   1 
ATOM 10184 C CA  . GLU D 1 205 ? 5.322   -65.487 48.610  1.00 52.91  ? 205 GLU D CA  1 
ATOM 10185 C C   . GLU D 1 205 ? 5.723   -65.826 50.042  1.00 44.05  ? 205 GLU D C   1 
ATOM 10186 O O   . GLU D 1 205 ? 5.474   -65.061 50.975  1.00 46.47  ? 205 GLU D O   1 
ATOM 10187 C CB  . GLU D 1 205 ? 4.446   -64.235 48.562  1.00 60.14  ? 205 GLU D CB  1 
ATOM 10188 C CG  . GLU D 1 205 ? 3.036   -64.435 49.114  1.00 57.36  ? 205 GLU D CG  1 
ATOM 10189 C CD  . GLU D 1 205 ? 2.327   -63.127 49.431  1.00 59.72  ? 205 GLU D CD  1 
ATOM 10190 O OE1 . GLU D 1 205 ? 2.984   -62.066 49.415  1.00 61.84  ? 205 GLU D OE1 1 
ATOM 10191 O OE2 . GLU D 1 205 ? 1.107   -63.163 49.705  1.00 57.77  ? 205 GLU D OE2 1 
ATOM 10192 N N   . GLY D 1 206 ? 6.354   -66.985 50.240  1.00 44.25  ? 206 GLY D N   1 
ATOM 10193 C CA  . GLY D 1 206 ? 6.820   -67.332 51.572  1.00 47.14  ? 206 GLY D CA  1 
ATOM 10194 C C   . GLY D 1 206 ? 7.856   -66.354 52.090  1.00 40.81  ? 206 GLY D C   1 
ATOM 10195 O O   . GLY D 1 206 ? 7.881   -66.033 53.282  1.00 30.51  ? 206 GLY D O   1 
ATOM 10196 N N   . LYS D 1 207 ? 8.712   -65.858 51.195  1.00 43.12  ? 207 LYS D N   1 
ATOM 10197 C CA  . LYS D 1 207 ? 9.704   -64.855 51.574  1.00 42.56  ? 207 LYS D CA  1 
ATOM 10198 C C   . LYS D 1 207 ? 9.032   -63.605 52.134  1.00 44.26  ? 207 LYS D C   1 
ATOM 10199 O O   . LYS D 1 207 ? 9.381   -63.130 53.224  1.00 46.73  ? 207 LYS D O   1 
ATOM 10200 C CB  . LYS D 1 207 ? 10.570  -64.515 50.359  1.00 49.82  ? 207 LYS D CB  1 
ATOM 10201 C CG  . LYS D 1 207 ? 11.443  -63.286 50.512  1.00 59.11  ? 207 LYS D CG  1 
ATOM 10202 C CD  . LYS D 1 207 ? 12.324  -63.097 49.280  1.00 67.12  ? 207 LYS D CD  1 
ATOM 10203 C CE  . LYS D 1 207 ? 11.497  -63.082 48.000  1.00 63.14  ? 207 LYS D CE  1 
ATOM 10204 N NZ  . LYS D 1 207 ? 12.354  -63.012 46.781  1.00 58.88  ? 207 LYS D NZ  1 
ATOM 10205 N N   . TYR D 1 208 ? 8.049   -63.070 51.412  1.00 45.53  ? 208 TYR D N   1 
ATOM 10206 C CA  . TYR D 1 208 ? 7.378   -61.859 51.869  1.00 46.43  ? 208 TYR D CA  1 
ATOM 10207 C C   . TYR D 1 208 ? 6.505   -62.125 53.088  1.00 41.85  ? 208 TYR D C   1 
ATOM 10208 O O   . TYR D 1 208 ? 6.326   -61.231 53.921  1.00 42.52  ? 208 TYR D O   1 
ATOM 10209 C CB  . TYR D 1 208 ? 6.558   -61.261 50.727  1.00 47.70  ? 208 TYR D CB  1 
ATOM 10210 C CG  . TYR D 1 208 ? 7.382   -60.998 49.486  1.00 47.82  ? 208 TYR D CG  1 
ATOM 10211 C CD1 . TYR D 1 208 ? 8.116   -59.828 49.353  1.00 50.87  ? 208 TYR D CD1 1 
ATOM 10212 C CD2 . TYR D 1 208 ? 7.433   -61.925 48.455  1.00 50.25  ? 208 TYR D CD2 1 
ATOM 10213 C CE1 . TYR D 1 208 ? 8.873   -59.584 48.224  1.00 57.06  ? 208 TYR D CE1 1 
ATOM 10214 C CE2 . TYR D 1 208 ? 8.189   -61.694 47.324  1.00 54.44  ? 208 TYR D CE2 1 
ATOM 10215 C CZ  . TYR D 1 208 ? 8.908   -60.522 47.212  1.00 53.60  ? 208 TYR D CZ  1 
ATOM 10216 O OH  . TYR D 1 208 ? 9.664   -60.285 46.085  1.00 56.57  ? 208 TYR D OH  1 
ATOM 10217 N N   . ILE D 1 209 ? 5.976   -63.341 53.230  1.00 41.53  ? 209 ILE D N   1 
ATOM 10218 C CA  . ILE D 1 209 ? 5.197   -63.665 54.421  1.00 46.04  ? 209 ILE D CA  1 
ATOM 10219 C C   . ILE D 1 209 ? 6.095   -63.688 55.651  1.00 47.61  ? 209 ILE D C   1 
ATOM 10220 O O   . ILE D 1 209 ? 5.728   -63.174 56.714  1.00 46.46  ? 209 ILE D O   1 
ATOM 10221 C CB  . ILE D 1 209 ? 4.453   -64.999 54.230  1.00 50.54  ? 209 ILE D CB  1 
ATOM 10222 C CG1 . ILE D 1 209 ? 3.255   -64.809 53.300  1.00 42.83  ? 209 ILE D CG1 1 
ATOM 10223 C CG2 . ILE D 1 209 ? 3.990   -65.559 55.566  1.00 53.55  ? 209 ILE D CG2 1 
ATOM 10224 C CD1 . ILE D 1 209 ? 2.467   -66.074 53.053  1.00 43.48  ? 209 ILE D CD1 1 
ATOM 10225 N N   . ASP D 1 210 ? 7.287   -64.273 55.531  1.00 46.06  ? 210 ASP D N   1 
ATOM 10226 C CA  . ASP D 1 210 ? 8.239   -64.241 56.637  1.00 42.59  ? 210 ASP D CA  1 
ATOM 10227 C C   . ASP D 1 210 ? 8.679   -62.812 56.944  1.00 46.69  ? 210 ASP D C   1 
ATOM 10228 O O   . ASP D 1 210 ? 8.823   -62.437 58.117  1.00 45.48  ? 210 ASP D O   1 
ATOM 10229 C CB  . ASP D 1 210 ? 9.444   -65.123 56.313  1.00 35.69  ? 210 ASP D CB  1 
ATOM 10230 C CG  . ASP D 1 210 ? 9.065   -66.584 56.148  1.00 48.30  ? 210 ASP D CG  1 
ATOM 10231 O OD1 . ASP D 1 210 ? 8.125   -67.031 56.843  1.00 62.39  ? 210 ASP D OD1 1 
ATOM 10232 O OD2 . ASP D 1 210 ? 9.699   -67.283 55.327  1.00 46.67  ? 210 ASP D OD2 1 
ATOM 10233 N N   . LEU D 1 211 ? 8.901   -62.005 55.901  1.00 49.55  ? 211 LEU D N   1 
ATOM 10234 C CA  . LEU D 1 211 ? 9.230   -60.601 56.125  1.00 45.07  ? 211 LEU D CA  1 
ATOM 10235 C C   . LEU D 1 211 ? 8.130   -59.898 56.909  1.00 48.03  ? 211 LEU D C   1 
ATOM 10236 O O   . LEU D 1 211 ? 8.409   -59.169 57.866  1.00 44.60  ? 211 LEU D O   1 
ATOM 10237 C CB  . LEU D 1 211 ? 9.475   -59.893 54.794  1.00 46.52  ? 211 LEU D CB  1 
ATOM 10238 C CG  . LEU D 1 211 ? 9.743   -58.388 54.870  1.00 52.05  ? 211 LEU D CG  1 
ATOM 10239 C CD1 . LEU D 1 211 ? 10.959  -58.096 55.732  1.00 44.99  ? 211 LEU D CD1 1 
ATOM 10240 C CD2 . LEU D 1 211 ? 9.913   -57.808 53.478  1.00 52.51  ? 211 LEU D CD2 1 
ATOM 10241 N N   . LEU D 1 212 ? 6.871   -60.117 56.517  1.00 49.67  ? 212 LEU D N   1 
ATOM 10242 C CA  . LEU D 1 212 ? 5.744   -59.501 57.213  1.00 49.16  ? 212 LEU D CA  1 
ATOM 10243 C C   . LEU D 1 212 ? 5.644   -59.995 58.651  1.00 48.47  ? 212 LEU D C   1 
ATOM 10244 O O   . LEU D 1 212 ? 5.309   -59.225 59.560  1.00 45.37  ? 212 LEU D O   1 
ATOM 10245 C CB  . LEU D 1 212 ? 4.452   -59.793 56.455  1.00 47.62  ? 212 LEU D CB  1 
ATOM 10246 C CG  . LEU D 1 212 ? 3.216   -58.952 56.773  1.00 51.84  ? 212 LEU D CG  1 
ATOM 10247 C CD1 . LEU D 1 212 ? 3.429   -57.520 56.318  1.00 46.33  ? 212 LEU D CD1 1 
ATOM 10248 C CD2 . LEU D 1 212 ? 1.977   -59.548 56.119  1.00 49.70  ? 212 LEU D CD2 1 
ATOM 10249 N N   . SER D 1 213 ? 5.922   -61.284 58.870  1.00 49.08  ? 213 SER D N   1 
ATOM 10250 C CA  . SER D 1 213 ? 5.960   -61.833 60.223  1.00 43.69  ? 213 SER D CA  1 
ATOM 10251 C C   . SER D 1 213 ? 6.959   -61.080 61.088  1.00 41.38  ? 213 SER D C   1 
ATOM 10252 O O   . SER D 1 213 ? 6.639   -60.656 62.204  1.00 47.60  ? 213 SER D O   1 
ATOM 10253 C CB  . SER D 1 213 ? 6.321   -63.319 60.186  1.00 41.42  ? 213 SER D CB  1 
ATOM 10254 O OG  . SER D 1 213 ? 5.312   -64.091 59.568  1.00 46.99  ? 213 SER D OG  1 
ATOM 10255 N N   . THR D 1 214 ? 8.186   -60.916 60.592  1.00 43.64  ? 214 THR D N   1 
ATOM 10256 C CA  . THR D 1 214 ? 9.191   -60.236 61.396  1.00 41.52  ? 214 THR D CA  1 
ATOM 10257 C C   . THR D 1 214 ? 8.867   -58.758 61.570  1.00 47.07  ? 214 THR D C   1 
ATOM 10258 O O   . THR D 1 214 ? 9.119   -58.191 62.640  1.00 50.96  ? 214 THR D O   1 
ATOM 10259 C CB  . THR D 1 214 ? 10.580  -60.404 60.782  1.00 42.58  ? 214 THR D CB  1 
ATOM 10260 O OG1 . THR D 1 214 ? 10.623  -59.750 59.509  1.00 64.93  ? 214 THR D OG1 1 
ATOM 10261 C CG2 . THR D 1 214 ? 10.906  -61.878 60.610  1.00 41.17  ? 214 THR D CG2 1 
ATOM 10262 N N   . LEU D 1 215 ? 8.295   -58.121 60.549  1.00 48.48  ? 215 LEU D N   1 
ATOM 10263 C CA  . LEU D 1 215 ? 8.024   -56.691 60.640  1.00 49.67  ? 215 LEU D CA  1 
ATOM 10264 C C   . LEU D 1 215 ? 6.880   -56.399 61.604  1.00 49.27  ? 215 LEU D C   1 
ATOM 10265 O O   . LEU D 1 215 ? 6.911   -55.398 62.325  1.00 48.55  ? 215 LEU D O   1 
ATOM 10266 C CB  . LEU D 1 215 ? 7.719   -56.121 59.253  1.00 48.35  ? 215 LEU D CB  1 
ATOM 10267 C CG  . LEU D 1 215 ? 8.922   -55.960 58.319  1.00 49.57  ? 215 LEU D CG  1 
ATOM 10268 C CD1 . LEU D 1 215 ? 8.468   -55.512 56.946  1.00 56.25  ? 215 LEU D CD1 1 
ATOM 10269 C CD2 . LEU D 1 215 ? 9.935   -54.981 58.902  1.00 55.14  ? 215 LEU D CD2 1 
ATOM 10270 N N   . SER D 1 216 ? 5.865   -57.263 61.639  1.00 47.89  ? 216 SER D N   1 
ATOM 10271 C CA  . SER D 1 216 ? 4.718   -57.037 62.505  1.00 46.27  ? 216 SER D CA  1 
ATOM 10272 C C   . SER D 1 216 ? 4.907   -57.587 63.912  1.00 56.68  ? 216 SER D C   1 
ATOM 10273 O O   . SER D 1 216 ? 4.108   -57.255 64.796  1.00 54.51  ? 216 SER D O   1 
ATOM 10274 C CB  . SER D 1 216 ? 3.461   -57.656 61.889  1.00 52.94  ? 216 SER D CB  1 
ATOM 10275 O OG  . SER D 1 216 ? 3.594   -59.059 61.754  1.00 40.29  ? 216 SER D OG  1 
ATOM 10276 N N   . ASP D 1 217 ? 5.944   -58.396 64.142  1.00 54.17  ? 217 ASP D N   1 
ATOM 10277 C CA  . ASP D 1 217 ? 6.124   -59.162 65.375  1.00 53.51  ? 217 ASP D CA  1 
ATOM 10278 C C   . ASP D 1 217 ? 4.955   -60.103 65.642  1.00 55.00  ? 217 ASP D C   1 
ATOM 10279 O O   . ASP D 1 217 ? 4.692   -60.469 66.792  1.00 71.10  ? 217 ASP D O   1 
ATOM 10280 C CB  . ASP D 1 217 ? 6.355   -58.246 66.586  1.00 67.35  ? 217 ASP D CB  1 
ATOM 10281 C CG  . ASP D 1 217 ? 7.663   -57.485 66.498  1.00 81.47  ? 217 ASP D CG  1 
ATOM 10282 O OD1 . ASP D 1 217 ? 8.343   -57.592 65.456  1.00 75.08  ? 217 ASP D OD1 1 
ATOM 10283 O OD2 . ASP D 1 217 ? 8.013   -56.784 67.474  1.00 87.94  ? 217 ASP D OD2 1 
ATOM 10284 N N   . LYS D 1 218 ? 4.240   -60.504 64.596  1.00 48.36  ? 218 LYS D N   1 
ATOM 10285 C CA  . LYS D 1 218 ? 3.138   -61.444 64.705  1.00 51.01  ? 218 LYS D CA  1 
ATOM 10286 C C   . LYS D 1 218 ? 3.408   -62.646 63.810  1.00 49.28  ? 218 LYS D C   1 
ATOM 10287 O O   . LYS D 1 218 ? 4.132   -62.549 62.817  1.00 54.67  ? 218 LYS D O   1 
ATOM 10288 C CB  . LYS D 1 218 ? 1.797   -60.802 64.316  1.00 43.30  ? 218 LYS D CB  1 
ATOM 10289 C CG  . LYS D 1 218 ? 1.051   -60.134 65.467  1.00 46.29  ? 218 LYS D CG  1 
ATOM 10290 C CD  . LYS D 1 218 ? 1.789   -58.914 65.981  1.00 57.43  ? 218 LYS D CD  1 
ATOM 10291 C CE  . LYS D 1 218 ? 0.966   -58.164 67.003  1.00 38.85  ? 218 LYS D CE  1 
ATOM 10292 N NZ  . LYS D 1 218 ? 0.544   -59.072 68.095  1.00 51.29  ? 218 LYS D NZ  1 
ATOM 10293 N N   . THR D 1 219 ? 2.825   -63.780 64.172  1.00 47.34  ? 219 THR D N   1 
ATOM 10294 C CA  . THR D 1 219 ? 2.972   -64.982 63.366  1.00 48.63  ? 219 THR D CA  1 
ATOM 10295 C C   . THR D 1 219 ? 1.960   -64.935 62.230  1.00 53.10  ? 219 THR D C   1 
ATOM 10296 O O   . THR D 1 219 ? 0.747   -64.920 62.467  1.00 58.68  ? 219 THR D O   1 
ATOM 10297 C CB  . THR D 1 219 ? 2.792   -66.236 64.219  1.00 50.29  ? 219 THR D CB  1 
ATOM 10298 O OG1 . THR D 1 219 ? 3.705   -66.193 65.323  1.00 50.98  ? 219 THR D OG1 1 
ATOM 10299 C CG2 . THR D 1 219 ? 3.079   -67.483 63.393  1.00 53.93  ? 219 THR D CG2 1 
ATOM 10300 N N   . LEU D 1 220 ? 2.453   -64.864 60.999  1.00 52.22  ? 220 LEU D N   1 
ATOM 10301 C CA  . LEU D 1 220 ? 1.583   -64.871 59.834  1.00 56.74  ? 220 LEU D CA  1 
ATOM 10302 C C   . LEU D 1 220 ? 1.104   -66.294 59.590  1.00 46.25  ? 220 LEU D C   1 
ATOM 10303 O O   . LEU D 1 220 ? 1.915   -67.198 59.359  1.00 49.91  ? 220 LEU D O   1 
ATOM 10304 C CB  . LEU D 1 220 ? 2.310   -64.321 58.610  1.00 51.17  ? 220 LEU D CB  1 
ATOM 10305 C CG  . LEU D 1 220 ? 2.071   -62.849 58.269  1.00 44.74  ? 220 LEU D CG  1 
ATOM 10306 C CD1 . LEU D 1 220 ? 0.629   -62.628 57.842  1.00 46.47  ? 220 LEU D CD1 1 
ATOM 10307 C CD2 . LEU D 1 220 ? 2.423   -61.946 59.441  1.00 44.85  ? 220 LEU D CD2 1 
ATOM 10308 N N   . VAL D 1 221 ? -0.204  -66.497 59.659  1.00 45.17  ? 221 VAL D N   1 
ATOM 10309 C CA  . VAL D 1 221 ? -0.805  -67.803 59.431  1.00 44.55  ? 221 VAL D CA  1 
ATOM 10310 C C   . VAL D 1 221 ? -1.521  -67.752 58.083  1.00 41.21  ? 221 VAL D C   1 
ATOM 10311 O O   . VAL D 1 221 ? -2.533  -67.045 57.939  1.00 47.15  ? 221 VAL D O   1 
ATOM 10312 C CB  . VAL D 1 221 ? -1.761  -68.195 60.564  1.00 46.68  ? 221 VAL D CB  1 
ATOM 10313 C CG1 . VAL D 1 221 ? -2.214  -69.627 60.387  1.00 48.35  ? 221 VAL D CG1 1 
ATOM 10314 C CG2 . VAL D 1 221 ? -1.077  -68.017 61.909  1.00 44.75  ? 221 VAL D CG2 1 
ATOM 10315 N N   . PRO D 1 222 ? -1.016  -68.438 57.064  1.00 34.82  ? 222 PRO D N   1 
ATOM 10316 C CA  . PRO D 1 222 ? -1.690  -68.436 55.764  1.00 34.17  ? 222 PRO D CA  1 
ATOM 10317 C C   . PRO D 1 222 ? -2.808  -69.463 55.713  1.00 41.18  ? 222 PRO D C   1 
ATOM 10318 O O   . PRO D 1 222 ? -2.663  -70.600 56.171  1.00 50.79  ? 222 PRO D O   1 
ATOM 10319 C CB  . PRO D 1 222 ? -0.561  -68.794 54.789  1.00 41.34  ? 222 PRO D CB  1 
ATOM 10320 C CG  . PRO D 1 222 ? 0.366   -69.638 55.605  1.00 36.66  ? 222 PRO D CG  1 
ATOM 10321 C CD  . PRO D 1 222 ? 0.300   -69.099 57.010  1.00 39.36  ? 222 PRO D CD  1 
ATOM 10322 N N   . VAL D 1 223 ? -3.938  -69.048 55.149  1.00 41.30  ? 223 VAL D N   1 
ATOM 10323 C CA  . VAL D 1 223 ? -5.091  -69.917 54.971  1.00 46.85  ? 223 VAL D CA  1 
ATOM 10324 C C   . VAL D 1 223 ? -5.252  -70.329 53.510  1.00 47.01  ? 223 VAL D C   1 
ATOM 10325 O O   . VAL D 1 223 ? -6.320  -70.790 53.108  1.00 50.42  ? 223 VAL D O   1 
ATOM 10326 C CB  . VAL D 1 223 ? -6.375  -69.262 55.508  1.00 46.55  ? 223 VAL D CB  1 
ATOM 10327 C CG1 . VAL D 1 223 ? -6.258  -69.015 57.006  1.00 53.83  ? 223 VAL D CG1 1 
ATOM 10328 C CG2 . VAL D 1 223 ? -6.655  -67.972 54.764  1.00 47.39  ? 223 VAL D CG2 1 
ATOM 10329 N N   . GLY D 1 224 ? -4.203  -70.164 52.706  1.00 52.92  ? 224 GLY D N   1 
ATOM 10330 C CA  . GLY D 1 224 ? -4.235  -70.546 51.316  1.00 56.02  ? 224 GLY D CA  1 
ATOM 10331 C C   . GLY D 1 224 ? -5.217  -69.718 50.518  1.00 50.56  ? 224 GLY D C   1 
ATOM 10332 O O   . GLY D 1 224 ? -5.672  -68.656 50.955  1.00 48.16  ? 224 GLY D O   1 
ATOM 10333 N N   . PRO D 1 225 ? -5.553  -70.179 49.320  1.00 55.48  ? 225 PRO D N   1 
ATOM 10334 C CA  . PRO D 1 225 ? -6.594  -69.515 48.537  1.00 61.06  ? 225 PRO D CA  1 
ATOM 10335 C C   . PRO D 1 225 ? -7.977  -69.979 48.969  1.00 68.09  ? 225 PRO D C   1 
ATOM 10336 O O   . PRO D 1 225 ? -8.147  -71.012 49.621  1.00 67.02  ? 225 PRO D O   1 
ATOM 10337 C CB  . PRO D 1 225 ? -6.287  -69.956 47.107  1.00 53.75  ? 225 PRO D CB  1 
ATOM 10338 C CG  . PRO D 1 225 ? -5.744  -71.331 47.285  1.00 54.21  ? 225 PRO D CG  1 
ATOM 10339 C CD  . PRO D 1 225 ? -4.960  -71.312 48.586  1.00 57.27  ? 225 PRO D CD  1 
ATOM 10340 N N   . LEU D 1 226 ? -8.975  -69.189 48.588  1.00 59.59  ? 226 LEU D N   1 
ATOM 10341 C CA  . LEU D 1 226 ? -10.370 -69.475 48.903  1.00 61.35  ? 226 LEU D CA  1 
ATOM 10342 C C   . LEU D 1 226 ? -11.158 -69.431 47.602  1.00 71.47  ? 226 LEU D C   1 
ATOM 10343 O O   . LEU D 1 226 ? -11.385 -68.348 47.052  1.00 80.46  ? 226 LEU D O   1 
ATOM 10344 C CB  . LEU D 1 226 ? -10.913 -68.476 49.923  1.00 67.71  ? 226 LEU D CB  1 
ATOM 10345 C CG  . LEU D 1 226 ? -10.168 -68.460 51.261  1.00 51.44  ? 226 LEU D CG  1 
ATOM 10346 C CD1 . LEU D 1 226 ? -10.087 -67.049 51.822  1.00 46.60  ? 226 LEU D CD1 1 
ATOM 10347 C CD2 . LEU D 1 226 ? -10.843 -69.393 52.259  1.00 64.16  ? 226 LEU D CD2 1 
ATOM 10348 N N   . VAL D 1 227 ? -11.575 -70.607 47.128  1.00 76.99  ? 227 VAL D N   1 
ATOM 10349 C CA  . VAL D 1 227 ? -12.182 -70.818 45.808  1.00 57.41  ? 227 VAL D CA  1 
ATOM 10350 C C   . VAL D 1 227 ? -11.506 -69.971 44.737  1.00 72.79  ? 227 VAL D C   1 
ATOM 10351 O O   . VAL D 1 227 ? -10.306 -70.107 44.500  1.00 83.90  ? 227 VAL D O   1 
ATOM 10352 C CB  . VAL D 1 227 ? -13.714 -70.561 45.828  1.00 64.89  ? 227 VAL D CB  1 
ATOM 10353 C CG1 . VAL D 1 227 ? -14.360 -71.255 47.017  1.00 66.63  ? 227 VAL D CG1 1 
ATOM 10354 C CG2 . VAL D 1 227 ? -14.048 -69.069 45.794  1.00 65.79  ? 227 VAL D CG2 1 
ATOM 10355 N N   . ASP D 1 236 ? -28.011 -66.807 35.001  1.00 154.17 ? 236 ASP D N   1 
ATOM 10356 C CA  . ASP D 1 236 ? -27.387 -68.084 35.342  1.00 160.15 ? 236 ASP D CA  1 
ATOM 10357 C C   . ASP D 1 236 ? -27.647 -69.192 34.309  1.00 156.88 ? 236 ASP D C   1 
ATOM 10358 O O   . ASP D 1 236 ? -26.783 -70.041 34.103  1.00 150.19 ? 236 ASP D O   1 
ATOM 10359 C CB  . ASP D 1 236 ? -27.841 -68.539 36.733  1.00 160.41 ? 236 ASP D CB  1 
ATOM 10360 C CG  . ASP D 1 236 ? -27.276 -67.671 37.838  1.00 158.43 ? 236 ASP D CG  1 
ATOM 10361 O OD1 . ASP D 1 236 ? -26.233 -67.021 37.609  1.00 160.13 ? 236 ASP D OD1 1 
ATOM 10362 O OD2 . ASP D 1 236 ? -27.868 -67.641 38.938  1.00 157.53 ? 236 ASP D OD2 1 
ATOM 10363 N N   . PRO D 1 237 ? -28.821 -69.210 33.668  1.00 156.88 ? 237 PRO D N   1 
ATOM 10364 C CA  . PRO D 1 237 ? -28.966 -70.032 32.454  1.00 151.28 ? 237 PRO D CA  1 
ATOM 10365 C C   . PRO D 1 237 ? -28.193 -69.500 31.257  1.00 147.08 ? 237 PRO D C   1 
ATOM 10366 O O   . PRO D 1 237 ? -28.286 -70.084 30.173  1.00 142.40 ? 237 PRO D O   1 
ATOM 10367 C CB  . PRO D 1 237 ? -30.479 -70.006 32.188  1.00 156.89 ? 237 PRO D CB  1 
ATOM 10368 C CG  . PRO D 1 237 ? -31.085 -69.735 33.509  1.00 156.25 ? 237 PRO D CG  1 
ATOM 10369 C CD  . PRO D 1 237 ? -30.140 -68.788 34.181  1.00 161.30 ? 237 PRO D CD  1 
ATOM 10370 N N   . LYS D 1 238 ? -27.437 -68.416 31.416  1.00 150.73 ? 238 LYS D N   1 
ATOM 10371 C CA  . LYS D 1 238 ? -26.672 -67.814 30.336  1.00 146.90 ? 238 LYS D CA  1 
ATOM 10372 C C   . LYS D 1 238 ? -25.248 -68.351 30.241  1.00 140.16 ? 238 LYS D C   1 
ATOM 10373 O O   . LYS D 1 238 ? -24.494 -67.909 29.366  1.00 137.04 ? 238 LYS D O   1 
ATOM 10374 C CB  . LYS D 1 238 ? -26.629 -66.291 30.508  1.00 147.28 ? 238 LYS D CB  1 
ATOM 10375 C CG  . LYS D 1 238 ? -25.940 -65.838 31.788  1.00 138.14 ? 238 LYS D CG  1 
ATOM 10376 C CD  . LYS D 1 238 ? -25.843 -64.322 31.873  1.00 128.39 ? 238 LYS D CD  1 
ATOM 10377 C CE  . LYS D 1 238 ? -25.043 -63.897 33.098  1.00 129.92 ? 238 LYS D CE  1 
ATOM 10378 N NZ  . LYS D 1 238 ? -24.875 -62.420 33.179  1.00 125.09 ? 238 LYS D NZ  1 
ATOM 10379 N N   . THR D 1 239 ? -24.860 -69.280 31.113  1.00 138.28 ? 239 THR D N   1 
ATOM 10380 C CA  . THR D 1 239 ? -23.497 -69.799 31.136  1.00 134.13 ? 239 THR D CA  1 
ATOM 10381 C C   . THR D 1 239 ? -23.350 -71.141 30.434  1.00 130.79 ? 239 THR D C   1 
ATOM 10382 O O   . THR D 1 239 ? -22.221 -71.623 30.292  1.00 125.72 ? 239 THR D O   1 
ATOM 10383 C CB  . THR D 1 239 ? -23.002 -69.943 32.579  1.00 135.05 ? 239 THR D CB  1 
ATOM 10384 O OG1 . THR D 1 239 ? -21.671 -70.465 32.570  1.00 134.50 ? 239 THR D OG1 1 
ATOM 10385 C CG2 . THR D 1 239 ? -23.891 -70.897 33.352  1.00 133.94 ? 239 THR D CG2 1 
ATOM 10386 N N   . GLU D 1 240 ? -24.452 -71.761 30.007  1.00 135.30 ? 240 GLU D N   1 
ATOM 10387 C CA  . GLU D 1 240 ? -24.358 -73.052 29.332  1.00 131.62 ? 240 GLU D CA  1 
ATOM 10388 C C   . GLU D 1 240 ? -23.619 -72.921 28.004  1.00 121.78 ? 240 GLU D C   1 
ATOM 10389 O O   . GLU D 1 240 ? -22.837 -73.802 27.632  1.00 108.05 ? 240 GLU D O   1 
ATOM 10390 C CB  . GLU D 1 240 ? -25.756 -73.629 29.122  1.00 134.89 ? 240 GLU D CB  1 
ATOM 10391 C CG  . GLU D 1 240 ? -26.756 -73.200 30.191  1.00 134.96 ? 240 GLU D CG  1 
ATOM 10392 C CD  . GLU D 1 240 ? -28.114 -73.865 30.039  1.00 134.97 ? 240 GLU D CD  1 
ATOM 10393 O OE1 . GLU D 1 240 ? -28.183 -74.962 29.447  1.00 121.54 ? 240 GLU D OE1 1 
ATOM 10394 O OE2 . GLU D 1 240 ? -29.115 -73.287 30.513  1.00 140.92 ? 240 GLU D OE2 1 
ATOM 10395 N N   . GLN D 1 241 ? -23.857 -71.820 27.282  1.00 125.48 ? 241 GLN D N   1 
ATOM 10396 C CA  . GLN D 1 241 ? -23.120 -71.567 26.048  1.00 123.76 ? 241 GLN D CA  1 
ATOM 10397 C C   . GLN D 1 241 ? -21.619 -71.519 26.304  1.00 124.12 ? 241 GLN D C   1 
ATOM 10398 O O   . GLN D 1 241 ? -20.831 -72.026 25.497  1.00 121.96 ? 241 GLN D O   1 
ATOM 10399 C CB  . GLN D 1 241 ? -23.597 -70.263 25.407  1.00 120.59 ? 241 GLN D CB  1 
ATOM 10400 C CG  . GLN D 1 241 ? -24.924 -70.360 24.657  1.00 120.49 ? 241 GLN D CG  1 
ATOM 10401 C CD  . GLN D 1 241 ? -26.138 -70.270 25.565  1.00 131.74 ? 241 GLN D CD  1 
ATOM 10402 O OE1 . GLN D 1 241 ? -26.193 -69.444 26.475  1.00 131.71 ? 241 GLN D OE1 1 
ATOM 10403 N NE2 . GLN D 1 241 ? -27.123 -71.124 25.313  1.00 140.17 ? 241 GLN D NE2 1 
ATOM 10404 N N   . ILE D 1 242 ? -21.206 -70.930 27.429  1.00 123.92 ? 242 ILE D N   1 
ATOM 10405 C CA  . ILE D 1 242 ? -19.783 -70.813 27.748  1.00 119.76 ? 242 ILE D CA  1 
ATOM 10406 C C   . ILE D 1 242 ? -19.135 -72.190 27.823  1.00 112.68 ? 242 ILE D C   1 
ATOM 10407 O O   . ILE D 1 242 ? -18.136 -72.466 27.149  1.00 103.12 ? 242 ILE D O   1 
ATOM 10408 C CB  . ILE D 1 242 ? -19.591 -70.033 29.062  1.00 126.21 ? 242 ILE D CB  1 
ATOM 10409 C CG1 . ILE D 1 242 ? -20.243 -68.655 28.969  1.00 129.59 ? 242 ILE D CG1 1 
ATOM 10410 C CG2 . ILE D 1 242 ? -18.113 -69.908 29.398  1.00 120.16 ? 242 ILE D CG2 1 
ATOM 10411 C CD1 . ILE D 1 242 ? -19.604 -67.747 27.947  1.00 131.31 ? 242 ILE D CD1 1 
ATOM 10412 N N   . ILE D 1 243 ? -19.689 -73.076 28.655  1.00 116.03 ? 243 ILE D N   1 
ATOM 10413 C CA  . ILE D 1 243 ? -19.085 -74.394 28.839  1.00 112.44 ? 243 ILE D CA  1 
ATOM 10414 C C   . ILE D 1 243 ? -19.211 -75.225 27.568  1.00 114.05 ? 243 ILE D C   1 
ATOM 10415 O O   . ILE D 1 243 ? -18.298 -75.984 27.217  1.00 113.35 ? 243 ILE D O   1 
ATOM 10416 C CB  . ILE D 1 243 ? -19.711 -75.105 30.053  1.00 112.06 ? 243 ILE D CB  1 
ATOM 10417 C CG1 . ILE D 1 243 ? -19.402 -74.333 31.338  1.00 116.39 ? 243 ILE D CG1 1 
ATOM 10418 C CG2 . ILE D 1 243 ? -19.194 -76.530 30.168  1.00 103.10 ? 243 ILE D CG2 1 
ATOM 10419 C CD1 . ILE D 1 243 ? -17.919 -74.199 31.633  1.00 123.51 ? 243 ILE D CD1 1 
ATOM 10420 N N   . ASN D 1 244 ? -20.332 -75.098 26.853  1.00 113.92 ? 244 ASN D N   1 
ATOM 10421 C CA  . ASN D 1 244 ? -20.485 -75.851 25.611  1.00 111.56 ? 244 ASN D CA  1 
ATOM 10422 C C   . ASN D 1 244 ? -19.448 -75.424 24.580  1.00 112.39 ? 244 ASN D C   1 
ATOM 10423 O O   . ASN D 1 244 ? -18.910 -76.262 23.846  1.00 108.84 ? 244 ASN D O   1 
ATOM 10424 C CB  . ASN D 1 244 ? -21.900 -75.678 25.055  1.00 120.07 ? 244 ASN D CB  1 
ATOM 10425 C CG  . ASN D 1 244 ? -22.159 -76.566 23.852  1.00 125.14 ? 244 ASN D CG  1 
ATOM 10426 O OD1 . ASN D 1 244 ? -21.516 -77.602 23.683  1.00 126.44 ? 244 ASN D OD1 1 
ATOM 10427 N ND2 . ASN D 1 244 ? -23.102 -76.162 23.008  1.00 126.06 ? 244 ASN D ND2 1 
ATOM 10428 N N   . TRP D 1 245 ? -18.983 -74.178 24.657  1.00 114.69 ? 245 TRP D N   1 
ATOM 10429 C CA  . TRP D 1 245 ? -17.938 -73.687 23.719  1.00 110.99 ? 245 TRP D CA  1 
ATOM 10430 C C   . TRP D 1 245 ? -16.554 -74.181 24.130  1.00 108.59 ? 245 TRP D C   1 
ATOM 10431 O O   . TRP D 1 245 ? -15.809 -74.590 23.246  1.00 102.54 ? 245 TRP D O   1 
ATOM 10432 C CB  . TRP D 1 245 ? -17.978 -72.160 23.668  1.00 106.71 ? 245 TRP D CB  1 
ATOM 10433 C CG  . TRP D 1 245 ? -17.063 -71.514 22.673  1.00 102.26 ? 245 TRP D CG  1 
ATOM 10434 C CD1 . TRP D 1 245 ? -17.401 -71.058 21.433  1.00 108.67 ? 245 TRP D CD1 1 
ATOM 10435 C CD2 . TRP D 1 245 ? -15.674 -71.186 22.852  1.00 106.35 ? 245 TRP D CD2 1 
ATOM 10436 N NE1 . TRP D 1 245 ? -16.314 -70.505 20.815  1.00 104.36 ? 245 TRP D NE1 1 
ATOM 10437 C CE2 . TRP D 1 245 ? -15.241 -70.565 21.660  1.00 105.44 ? 245 TRP D CE2 1 
ATOM 10438 C CE3 . TRP D 1 245 ? -14.752 -71.369 23.885  1.00 101.75 ? 245 TRP D CE3 1 
ATOM 10439 C CZ2 . TRP D 1 245 ? -13.932 -70.128 21.483  1.00 97.91  ? 245 TRP D CZ2 1 
ATOM 10440 C CZ3 . TRP D 1 245 ? -13.458 -70.939 23.707  1.00 101.53 ? 245 TRP D CZ3 1 
ATOM 10441 C CH2 . TRP D 1 245 ? -13.056 -70.330 22.520  1.00 101.49 ? 245 TRP D CH2 1 
ATOM 10442 N N   . LEU D 1 246 ? -16.234 -74.140 25.421  1.00 107.94 ? 246 LEU D N   1 
ATOM 10443 C CA  . LEU D 1 246 ? -14.873 -74.482 25.911  1.00 106.51 ? 246 LEU D CA  1 
ATOM 10444 C C   . LEU D 1 246 ? -14.636 -75.983 25.830  1.00 103.04 ? 246 LEU D C   1 
ATOM 10445 O O   . LEU D 1 246 ? -13.479 -76.375 25.696  1.00 97.97  ? 246 LEU D O   1 
ATOM 10446 C CB  . LEU D 1 246 ? -14.759 -73.981 27.353  1.00 101.11 ? 246 LEU D CB  1 
ATOM 10447 C CG  . LEU D 1 246 ? -13.352 -73.724 27.880  1.00 99.74  ? 246 LEU D CG  1 
ATOM 10448 C CD1 . LEU D 1 246 ? -12.660 -72.664 27.048  1.00 97.29  ? 246 LEU D CD1 1 
ATOM 10449 C CD2 . LEU D 1 246 ? -13.412 -73.285 29.331  1.00 108.50 ? 246 LEU D CD2 1 
ATOM 10450 N N   . ASP D 1 247 ? -15.688 -76.775 25.911  1.00 105.21 ? 247 ASP D N   1 
ATOM 10451 C CA  . ASP D 1 247 ? -15.494 -78.241 25.948  1.00 106.36 ? 247 ASP D CA  1 
ATOM 10452 C C   . ASP D 1 247 ? -15.119 -78.744 24.560  1.00 104.14 ? 247 ASP D C   1 
ATOM 10453 O O   . ASP D 1 247 ? -14.430 -79.767 24.483  1.00 98.40  ? 247 ASP D O   1 
ATOM 10454 C CB  . ASP D 1 247 ? -16.735 -78.955 26.479  1.00 113.30 ? 247 ASP D CB  1 
ATOM 10455 C CG  . ASP D 1 247 ? -17.192 -78.467 27.839  1.00 114.86 ? 247 ASP D CG  1 
ATOM 10456 O OD1 . ASP D 1 247 ? -16.587 -77.507 28.342  1.00 112.92 ? 247 ASP D OD1 1 
ATOM 10457 O OD2 . ASP D 1 247 ? -18.141 -79.057 28.386  1.00 109.97 ? 247 ASP D OD2 1 
ATOM 10458 N N   . LYS D 1 248 ? -15.529 -78.029 23.517  1.00 111.21 ? 248 LYS D N   1 
ATOM 10459 C CA  . LYS D 1 248 ? -15.290 -78.499 22.133  1.00 112.93 ? 248 LYS D CA  1 
ATOM 10460 C C   . LYS D 1 248 ? -13.958 -77.967 21.613  1.00 112.89 ? 248 LYS D C   1 
ATOM 10461 O O   . LYS D 1 248 ? -13.771 -77.952 20.390  1.00 112.59 ? 248 LYS D O   1 
ATOM 10462 C CB  . LYS D 1 248 ? -16.469 -78.082 21.258  1.00 111.91 ? 248 LYS D CB  1 
ATOM 10463 C CG  . LYS D 1 248 ? -16.892 -79.112 20.220  1.00 114.98 ? 248 LYS D CG  1 
ATOM 10464 C CD  . LYS D 1 248 ? -16.861 -80.526 20.751  1.00 114.40 ? 248 LYS D CD  1 
ATOM 10465 C CE  . LYS D 1 248 ? -17.728 -81.480 19.960  1.00 116.82 ? 248 LYS D CE  1 
ATOM 10466 N NZ  . LYS D 1 248 ? -19.165 -81.148 20.096  1.00 129.97 ? 248 LYS D NZ  1 
ATOM 10467 N N   . ARG D 1 249 ? -13.066 -77.561 22.513  1.00 111.18 ? 249 ARG D N   1 
ATOM 10468 C CA  . ARG D 1 249 ? -11.730 -77.053 22.131  1.00 102.92 ? 249 ARG D CA  1 
ATOM 10469 C C   . ARG D 1 249 ? -10.704 -77.915 22.835  1.00 99.29  ? 249 ARG D C   1 
ATOM 10470 O O   . ARG D 1 249 ? -11.030 -78.487 23.880  1.00 92.10  ? 249 ARG D O   1 
ATOM 10471 C CB  . ARG D 1 249 ? -11.562 -75.606 22.582  1.00 97.43  ? 249 ARG D CB  1 
ATOM 10472 C CG  . ARG D 1 249 ? -12.849 -74.796 22.635  1.00 106.63 ? 249 ARG D CG  1 
ATOM 10473 C CD  . ARG D 1 249 ? -13.423 -74.417 21.284  1.00 101.68 ? 249 ARG D CD  1 
ATOM 10474 N NE  . ARG D 1 249 ? -12.657 -73.367 20.641  1.00 95.48  ? 249 ARG D NE  1 
ATOM 10475 C CZ  . ARG D 1 249 ? -11.959 -73.531 19.526  1.00 99.40  ? 249 ARG D CZ  1 
ATOM 10476 N NH1 . ARG D 1 249 ? -11.759 -74.744 19.048  1.00 105.83 ? 249 ARG D NH1 1 
ATOM 10477 N NH2 . ARG D 1 249 ? -11.450 -72.486 18.901  1.00 95.00  ? 249 ARG D NH2 1 
ATOM 10478 N N   . ALA D 1 250 ? -9.495  -77.961 22.310  1.00 96.07  ? 250 ALA D N   1 
ATOM 10479 C CA  . ALA D 1 250 ? -8.495  -78.892 22.875  1.00 99.52  ? 250 ALA D CA  1 
ATOM 10480 C C   . ALA D 1 250 ? -7.987  -78.454 24.249  1.00 104.13 ? 250 ALA D C   1 
ATOM 10481 O O   . ALA D 1 250 ? -8.373  -77.391 24.722  1.00 103.87 ? 250 ALA D O   1 
ATOM 10482 C CB  . ALA D 1 250 ? -7.363  -79.067 21.902  1.00 96.94  ? 250 ALA D CB  1 
ATOM 10483 N N   . GLU D 1 251 ? -7.114  -79.264 24.837  1.00 104.28 ? 251 GLU D N   1 
ATOM 10484 C CA  . GLU D 1 251 ? -6.660  -79.003 26.196  1.00 109.61 ? 251 GLU D CA  1 
ATOM 10485 C C   . GLU D 1 251 ? -5.588  -77.920 26.209  1.00 109.57 ? 251 GLU D C   1 
ATOM 10486 O O   . GLU D 1 251 ? -4.667  -77.931 25.385  1.00 100.91 ? 251 GLU D O   1 
ATOM 10487 C CB  . GLU D 1 251 ? -6.115  -80.284 26.830  1.00 110.73 ? 251 GLU D CB  1 
ATOM 10488 C CG  . GLU D 1 251 ? -7.060  -80.945 27.825  1.00 114.43 ? 251 GLU D CG  1 
ATOM 10489 C CD  . GLU D 1 251 ? -6.389  -82.043 28.634  1.00 127.73 ? 251 GLU D CD  1 
ATOM 10490 O OE1 . GLU D 1 251 ? -5.181  -82.281 28.426  1.00 131.50 ? 251 GLU D OE1 1 
ATOM 10491 O OE2 . GLU D 1 251 ? -7.068  -82.665 29.477  1.00 130.62 ? 251 GLU D OE2 1 
ATOM 10492 N N   . SER D 1 252 ? -5.718  -76.981 27.148  1.00 105.24 ? 252 SER D N   1 
ATOM 10493 C CA  . SER D 1 252 ? -4.719  -75.938 27.385  1.00 101.47 ? 252 SER D CA  1 
ATOM 10494 C C   . SER D 1 252 ? -4.453  -75.109 26.128  1.00 92.13  ? 252 SER D C   1 
ATOM 10495 O O   . SER D 1 252 ? -3.318  -74.718 25.848  1.00 90.37  ? 252 SER D O   1 
ATOM 10496 C CB  . SER D 1 252 ? -3.419  -76.538 27.925  1.00 89.57  ? 252 SER D CB  1 
ATOM 10497 O OG  . SER D 1 252 ? -3.656  -77.286 29.104  1.00 86.96  ? 252 SER D OG  1 
ATOM 10498 N N   . THR D 1 253 ? -5.512  -74.838 25.365  1.00 88.82  ? 253 THR D N   1 
ATOM 10499 C CA  . THR D 1 253 ? -5.408  -74.017 24.169  1.00 87.23  ? 253 THR D CA  1 
ATOM 10500 C C   . THR D 1 253 ? -6.220  -72.731 24.241  1.00 88.07  ? 253 THR D C   1 
ATOM 10501 O O   . THR D 1 253 ? -6.061  -71.874 23.364  1.00 89.07  ? 253 THR D O   1 
ATOM 10502 C CB  . THR D 1 253 ? -5.849  -74.808 22.927  1.00 93.81  ? 253 THR D CB  1 
ATOM 10503 O OG1 . THR D 1 253 ? -7.210  -75.231 23.086  1.00 100.34 ? 253 THR D OG1 1 
ATOM 10504 C CG2 . THR D 1 253 ? -4.965  -76.029 22.731  1.00 99.05  ? 253 THR D CG2 1 
ATOM 10505 N N   . VAL D 1 254 ? -7.077  -72.572 25.245  1.00 94.62  ? 254 VAL D N   1 
ATOM 10506 C CA  . VAL D 1 254 ? -7.927  -71.397 25.389  1.00 90.74  ? 254 VAL D CA  1 
ATOM 10507 C C   . VAL D 1 254 ? -7.286  -70.442 26.385  1.00 86.06  ? 254 VAL D C   1 
ATOM 10508 O O   . VAL D 1 254 ? -6.778  -70.863 27.432  1.00 83.18  ? 254 VAL D O   1 
ATOM 10509 C CB  . VAL D 1 254 ? -9.348  -71.787 25.836  1.00 92.58  ? 254 VAL D CB  1 
ATOM 10510 C CG1 . VAL D 1 254 ? -10.271 -70.578 25.798  1.00 89.77  ? 254 VAL D CG1 1 
ATOM 10511 C CG2 . VAL D 1 254 ? -9.887  -72.911 24.967  1.00 99.11  ? 254 VAL D CG2 1 
ATOM 10512 N N   . VAL D 1 255 ? -7.307  -69.153 26.059  1.00 80.97  ? 255 VAL D N   1 
ATOM 10513 C CA  . VAL D 1 255 ? -6.790  -68.103 26.924  1.00 79.44  ? 255 VAL D CA  1 
ATOM 10514 C C   . VAL D 1 255 ? -7.979  -67.311 27.449  1.00 83.50  ? 255 VAL D C   1 
ATOM 10515 O O   . VAL D 1 255 ? -8.759  -66.753 26.669  1.00 85.23  ? 255 VAL D O   1 
ATOM 10516 C CB  . VAL D 1 255 ? -5.798  -67.194 26.181  1.00 77.33  ? 255 VAL D CB  1 
ATOM 10517 C CG1 . VAL D 1 255 ? -5.210  -66.162 27.127  1.00 78.31  ? 255 VAL D CG1 1 
ATOM 10518 C CG2 . VAL D 1 255 ? -4.699  -68.027 25.543  1.00 87.56  ? 255 VAL D CG2 1 
ATOM 10519 N N   . PHE D 1 256 ? -8.130  -67.279 28.768  1.00 76.78  ? 256 PHE D N   1 
ATOM 10520 C CA  . PHE D 1 256 ? -9.204  -66.530 29.403  1.00 72.45  ? 256 PHE D CA  1 
ATOM 10521 C C   . PHE D 1 256 ? -8.733  -65.113 29.693  1.00 78.03  ? 256 PHE D C   1 
ATOM 10522 O O   . PHE D 1 256 ? -7.697  -64.912 30.332  1.00 83.58  ? 256 PHE D O   1 
ATOM 10523 C CB  . PHE D 1 256 ? -9.658  -67.218 30.691  1.00 72.56  ? 256 PHE D CB  1 
ATOM 10524 C CG  . PHE D 1 256 ? -10.745 -66.481 31.418  1.00 77.92  ? 256 PHE D CG  1 
ATOM 10525 C CD1 . PHE D 1 256 ? -12.023 -66.410 30.889  1.00 83.89  ? 256 PHE D CD1 1 
ATOM 10526 C CD2 . PHE D 1 256 ? -10.492 -65.866 32.631  1.00 73.45  ? 256 PHE D CD2 1 
ATOM 10527 C CE1 . PHE D 1 256 ? -13.026 -65.734 31.553  1.00 85.57  ? 256 PHE D CE1 1 
ATOM 10528 C CE2 . PHE D 1 256 ? -11.494 -65.186 33.302  1.00 77.06  ? 256 PHE D CE2 1 
ATOM 10529 C CZ  . PHE D 1 256 ? -12.762 -65.123 32.764  1.00 86.57  ? 256 PHE D CZ  1 
ATOM 10530 N N   . VAL D 1 257 ? -9.488  -64.132 29.206  1.00 80.78  ? 257 VAL D N   1 
ATOM 10531 C CA  . VAL D 1 257 ? -9.153  -62.724 29.348  1.00 82.04  ? 257 VAL D CA  1 
ATOM 10532 C C   . VAL D 1 257 ? -10.248 -62.064 30.164  1.00 85.98  ? 257 VAL D C   1 
ATOM 10533 O O   . VAL D 1 257 ? -11.437 -62.221 29.865  1.00 90.58  ? 257 VAL D O   1 
ATOM 10534 C CB  . VAL D 1 257 ? -8.996  -62.032 27.981  1.00 81.16  ? 257 VAL D CB  1 
ATOM 10535 C CG1 . VAL D 1 257 ? -8.488  -60.604 28.168  1.00 88.14  ? 257 VAL D CG1 1 
ATOM 10536 C CG2 . VAL D 1 257 ? -8.055  -62.833 27.095  1.00 81.93  ? 257 VAL D CG2 1 
ATOM 10537 N N   . CYS D 1 258 ? -9.841  -61.374 31.238  1.00 79.55  ? 258 CYS D N   1 
ATOM 10538 C CA  . CYS D 1 258 ? -10.803 -60.602 32.066  1.00 80.45  ? 258 CYS D CA  1 
ATOM 10539 C C   . CYS D 1 258 ? -10.043 -59.559 32.876  1.00 69.27  ? 258 CYS D C   1 
ATOM 10540 O O   . CYS D 1 258 ? -8.974  -59.886 33.383  1.00 74.70  ? 258 CYS D O   1 
ATOM 10541 C CB  . CYS D 1 258 ? -11.588 -61.488 33.016  1.00 76.49  ? 258 CYS D CB  1 
ATOM 10542 S SG  . CYS D 1 258 ? -12.977 -60.624 33.791  1.00 83.34  ? 258 CYS D SG  1 
ATOM 10543 N N   . PHE D 1 259 ? -10.580 -58.341 32.970  1.00 71.08  ? 259 PHE D N   1 
ATOM 10544 C CA  . PHE D 1 259 ? -9.931  -57.275 33.779  1.00 79.19  ? 259 PHE D CA  1 
ATOM 10545 C C   . PHE D 1 259 ? -10.849 -56.922 34.950  1.00 84.47  ? 259 PHE D C   1 
ATOM 10546 O O   . PHE D 1 259 ? -11.000 -55.726 35.256  1.00 85.58  ? 259 PHE D O   1 
ATOM 10547 C CB  . PHE D 1 259 ? -9.538  -56.096 32.886  1.00 88.87  ? 259 PHE D CB  1 
ATOM 10548 C CG  . PHE D 1 259 ? -8.639  -56.492 31.743  1.00 88.95  ? 259 PHE D CG  1 
ATOM 10549 C CD1 . PHE D 1 259 ? -7.364  -56.979 31.980  1.00 81.50  ? 259 PHE D CD1 1 
ATOM 10550 C CD2 . PHE D 1 259 ? -9.080  -56.413 30.430  1.00 83.38  ? 259 PHE D CD2 1 
ATOM 10551 C CE1 . PHE D 1 259 ? -6.542  -57.358 30.932  1.00 79.59  ? 259 PHE D CE1 1 
ATOM 10552 C CE2 . PHE D 1 259 ? -8.255  -56.789 29.382  1.00 81.46  ? 259 PHE D CE2 1 
ATOM 10553 C CZ  . PHE D 1 259 ? -6.988  -57.261 29.635  1.00 73.21  ? 259 PHE D CZ  1 
ATOM 10554 N N   . GLY D 1 260 ? -11.447 -57.942 35.576  1.00 83.56  ? 260 GLY D N   1 
ATOM 10555 C CA  . GLY D 1 260 ? -12.347 -57.719 36.723  1.00 89.16  ? 260 GLY D CA  1 
ATOM 10556 C C   . GLY D 1 260 ? -13.454 -56.736 36.397  1.00 98.93  ? 260 GLY D C   1 
ATOM 10557 O O   . GLY D 1 260 ? -14.105 -56.908 35.346  1.00 91.33  ? 260 GLY D O   1 
ATOM 10558 N N   . SER D 1 261 ? -13.644 -55.722 37.245  1.00 109.17 ? 261 SER D N   1 
ATOM 10559 C CA  . SER D 1 261 ? -14.663 -54.670 36.984  1.00 113.44 ? 261 SER D CA  1 
ATOM 10560 C C   . SER D 1 261 ? -14.071 -53.308 37.352  1.00 115.34 ? 261 SER D C   1 
ATOM 10561 O O   . SER D 1 261 ? -14.842 -52.331 37.426  1.00 116.56 ? 261 SER D O   1 
ATOM 10562 C CB  . SER D 1 261 ? -15.925 -54.941 37.757  1.00 106.21 ? 261 SER D CB  1 
ATOM 10563 O OG  . SER D 1 261 ? -15.668 -54.934 39.153  1.00 107.78 ? 261 SER D OG  1 
ATOM 10564 N N   . GLU D 1 262 ? -12.755 -53.254 37.574  1.00 115.89 ? 262 GLU D N   1 
ATOM 10565 C CA  . GLU D 1 262 ? -12.093 -51.989 37.991  1.00 123.62 ? 262 GLU D CA  1 
ATOM 10566 C C   . GLU D 1 262 ? -12.221 -50.944 36.877  1.00 130.58 ? 262 GLU D C   1 
ATOM 10567 O O   . GLU D 1 262 ? -12.676 -49.822 37.176  1.00 129.42 ? 262 GLU D O   1 
ATOM 10568 C CB  . GLU D 1 262 ? -10.625 -52.251 38.325  1.00 118.20 ? 262 GLU D CB  1 
ATOM 10569 C CG  . GLU D 1 262 ? -10.429 -53.115 39.556  1.00 115.83 ? 262 GLU D CG  1 
ATOM 10570 C CD  . GLU D 1 262 ? -8.985  -53.460 39.885  1.00 113.93 ? 262 GLU D CD  1 
ATOM 10571 O OE1 . GLU D 1 262 ? -8.107  -53.186 39.047  1.00 112.38 ? 262 GLU D OE1 1 
ATOM 10572 O OE2 . GLU D 1 262 ? -8.742  -53.994 40.983  1.00 115.92 ? 262 GLU D OE2 1 
ATOM 10573 N N   . TYR D 1 263 ? -11.836 -51.301 35.647  1.00 136.06 ? 263 TYR D N   1 
ATOM 10574 C CA  . TYR D 1 263 ? -11.870 -50.335 34.526  1.00 141.67 ? 263 TYR D CA  1 
ATOM 10575 C C   . TYR D 1 263 ? -12.340 -51.039 33.251  1.00 145.42 ? 263 TYR D C   1 
ATOM 10576 O O   . TYR D 1 263 ? -11.687 -52.022 32.846  1.00 145.17 ? 263 TYR D O   1 
ATOM 10577 C CB  . TYR D 1 263 ? -10.495 -49.701 34.309  1.00 137.62 ? 263 TYR D CB  1 
ATOM 10578 C CG  . TYR D 1 263 ? -9.420  -50.688 33.913  1.00 135.28 ? 263 TYR D CG  1 
ATOM 10579 C CD1 . TYR D 1 263 ? -9.188  -50.992 32.576  1.00 138.14 ? 263 TYR D CD1 1 
ATOM 10580 C CD2 . TYR D 1 263 ? -8.637  -51.312 34.874  1.00 130.39 ? 263 TYR D CD2 1 
ATOM 10581 C CE1 . TYR D 1 263 ? -8.207  -51.893 32.211  1.00 132.28 ? 263 TYR D CE1 1 
ATOM 10582 C CE2 . TYR D 1 263 ? -7.652  -52.215 34.516  1.00 127.03 ? 263 TYR D CE2 1 
ATOM 10583 C CZ  . TYR D 1 263 ? -7.441  -52.501 33.183  1.00 126.62 ? 263 TYR D CZ  1 
ATOM 10584 O OH  . TYR D 1 263 ? -6.464  -53.399 32.821  1.00 112.21 ? 263 TYR D OH  1 
ATOM 10585 N N   . PHE D 1 264 ? -13.436 -50.561 32.654  1.00 142.83 ? 264 PHE D N   1 
ATOM 10586 C CA  . PHE D 1 264 ? -13.917 -51.127 31.366  1.00 143.92 ? 264 PHE D CA  1 
ATOM 10587 C C   . PHE D 1 264 ? -12.970 -50.656 30.259  1.00 146.79 ? 264 PHE D C   1 
ATOM 10588 O O   . PHE D 1 264 ? -13.301 -50.899 29.077  1.00 147.09 ? 264 PHE D O   1 
ATOM 10589 C CB  . PHE D 1 264 ? -15.360 -50.684 31.101  1.00 148.70 ? 264 PHE D CB  1 
ATOM 10590 C CG  . PHE D 1 264 ? -15.531 -49.261 30.623  1.00 157.56 ? 264 PHE D CG  1 
ATOM 10591 C CD1 . PHE D 1 264 ? -15.313 -48.188 31.473  1.00 157.45 ? 264 PHE D CD1 1 
ATOM 10592 C CD2 . PHE D 1 264 ? -15.927 -48.994 29.320  1.00 155.28 ? 264 PHE D CD2 1 
ATOM 10593 C CE1 . PHE D 1 264 ? -15.470 -46.885 31.029  1.00 159.10 ? 264 PHE D CE1 1 
ATOM 10594 C CE2 . PHE D 1 264 ? -16.081 -47.690 28.877  1.00 149.66 ? 264 PHE D CE2 1 
ATOM 10595 C CZ  . PHE D 1 264 ? -15.855 -46.638 29.733  1.00 156.75 ? 264 PHE D CZ  1 
ATOM 10596 N N   . LEU D 1 265 ? -11.851 -50.016 30.634  1.00 143.70 ? 265 LEU D N   1 
ATOM 10597 C CA  . LEU D 1 265 ? -10.882 -49.450 29.651  1.00 141.07 ? 265 LEU D CA  1 
ATOM 10598 C C   . LEU D 1 265 ? -11.600 -48.367 28.841  1.00 140.99 ? 265 LEU D C   1 
ATOM 10599 O O   . LEU D 1 265 ? -12.382 -47.607 29.448  1.00 142.96 ? 265 LEU D O   1 
ATOM 10600 C CB  . LEU D 1 265 ? -10.287 -50.549 28.759  1.00 137.75 ? 265 LEU D CB  1 
ATOM 10601 C CG  . LEU D 1 265 ? -9.332  -50.073 27.664  1.00 137.05 ? 265 LEU D CG  1 
ATOM 10602 C CD1 . LEU D 1 265 ? -8.099  -49.415 28.263  1.00 133.92 ? 265 LEU D CD1 1 
ATOM 10603 C CD2 . LEU D 1 265 ? -8.937  -51.223 26.749  1.00 131.62 ? 265 LEU D CD2 1 
ATOM 10604 N N   . SER D 1 266 ? -11.337 -48.294 27.535  1.00 134.89 ? 266 SER D N   1 
ATOM 10605 C CA  . SER D 1 266 ? -12.024 -47.308 26.662  1.00 134.44 ? 266 SER D CA  1 
ATOM 10606 C C   . SER D 1 266 ? -11.992 -47.836 25.229  1.00 133.86 ? 266 SER D C   1 
ATOM 10607 O O   . SER D 1 266 ? -11.290 -48.813 25.008  1.00 132.55 ? 266 SER D O   1 
ATOM 10608 C CB  . SER D 1 266 ? -11.364 -45.957 26.746  1.00 134.24 ? 266 SER D CB  1 
ATOM 10609 O OG  . SER D 1 266 ? -10.103 -45.972 26.097  1.00 136.71 ? 266 SER D OG  1 
ATOM 10610 N N   . ASN D 1 267 ? -12.729 -47.217 24.306  1.00 133.73 ? 267 ASN D N   1 
ATOM 10611 C CA  . ASN D 1 267 ? -12.694 -47.618 22.876  1.00 135.78 ? 267 ASN D CA  1 
ATOM 10612 C C   . ASN D 1 267 ? -11.255 -47.550 22.364  1.00 137.42 ? 267 ASN D C   1 
ATOM 10613 O O   . ASN D 1 267 ? -10.971 -48.154 21.318  1.00 139.28 ? 267 ASN D O   1 
ATOM 10614 C CB  . ASN D 1 267 ? -13.666 -46.815 22.010  1.00 140.51 ? 267 ASN D CB  1 
ATOM 10615 C CG  . ASN D 1 267 ? -13.175 -45.427 21.659  1.00 144.26 ? 267 ASN D CG  1 
ATOM 10616 O OD1 . ASN D 1 267 ? -12.745 -45.184 20.535  1.00 145.25 ? 267 ASN D OD1 1 
ATOM 10617 N ND2 . ASN D 1 267 ? -13.261 -44.507 22.605  1.00 145.47 ? 267 ASN D ND2 1 
ATOM 10618 N N   . GLU D 1 268 ? -10.383 -46.848 23.084  1.00 137.51 ? 268 GLU D N   1 
ATOM 10619 C CA  . GLU D 1 268 ? -8.995  -46.697 22.601  1.00 141.39 ? 268 GLU D CA  1 
ATOM 10620 C C   . GLU D 1 268 ? -8.182  -47.862 23.148  1.00 137.99 ? 268 GLU D C   1 
ATOM 10621 O O   . GLU D 1 268 ? -7.269  -48.334 22.448  1.00 132.66 ? 268 GLU D O   1 
ATOM 10622 C CB  . GLU D 1 268 ? -8.429  -45.367 23.088  1.00 140.02 ? 268 GLU D CB  1 
ATOM 10623 C CG  . GLU D 1 268 ? -8.544  -44.253 22.063  1.00 141.98 ? 268 GLU D CG  1 
ATOM 10624 C CD  . GLU D 1 268 ? -9.930  -43.641 21.940  1.00 140.07 ? 268 GLU D CD  1 
ATOM 10625 O OE1 . GLU D 1 268 ? -10.596 -43.485 22.979  1.00 136.30 ? 268 GLU D OE1 1 
ATOM 10626 O OE2 . GLU D 1 268 ? -10.339 -43.327 20.806  1.00 131.30 ? 268 GLU D OE2 1 
ATOM 10627 N N   . GLU D 1 269 ? -8.517  -48.296 24.359  1.00 137.78 ? 269 GLU D N   1 
ATOM 10628 C CA  . GLU D 1 269 ? -7.741  -49.383 24.992  1.00 136.68 ? 269 GLU D CA  1 
ATOM 10629 C C   . GLU D 1 269 ? -8.374  -50.723 24.633  1.00 126.71 ? 269 GLU D C   1 
ATOM 10630 O O   . GLU D 1 269 ? -7.614  -51.690 24.497  1.00 126.42 ? 269 GLU D O   1 
ATOM 10631 C CB  . GLU D 1 269 ? -7.602  -49.119 26.487  1.00 136.73 ? 269 GLU D CB  1 
ATOM 10632 C CG  . GLU D 1 269 ? -7.113  -47.714 26.795  1.00 141.59 ? 269 GLU D CG  1 
ATOM 10633 C CD  . GLU D 1 269 ? -6.160  -47.602 27.973  1.00 151.81 ? 269 GLU D CD  1 
ATOM 10634 O OE1 . GLU D 1 269 ? -5.403  -48.561 28.217  1.00 152.22 ? 269 GLU D OE1 1 
ATOM 10635 O OE2 . GLU D 1 269 ? -6.181  -46.556 28.652  1.00 152.88 ? 269 GLU D OE2 1 
ATOM 10636 N N   . LEU D 1 270 ? -9.703  -50.785 24.476  1.00 119.83 ? 270 LEU D N   1 
ATOM 10637 C CA  . LEU D 1 270 ? -10.239 -52.062 24.019  1.00 115.57 ? 270 LEU D CA  1 
ATOM 10638 C C   . LEU D 1 270 ? -9.648  -52.463 22.676  1.00 121.92 ? 270 LEU D C   1 
ATOM 10639 O O   . LEU D 1 270 ? -9.492  -53.657 22.403  1.00 121.49 ? 270 LEU D O   1 
ATOM 10640 C CB  . LEU D 1 270 ? -11.763 -51.992 23.911  1.00 109.93 ? 270 LEU D CB  1 
ATOM 10641 C CG  . LEU D 1 270 ? -12.595 -51.930 25.194  1.00 106.78 ? 270 LEU D CG  1 
ATOM 10642 C CD1 . LEU D 1 270 ? -14.026 -51.530 24.873  1.00 107.58 ? 270 LEU D CD1 1 
ATOM 10643 C CD2 . LEU D 1 270 ? -12.561 -53.257 25.928  1.00 108.81 ? 270 LEU D CD2 1 
ATOM 10644 N N   . GLU D 1 271 ? -9.318  -51.485 21.830  1.00 126.32 ? 271 GLU D N   1 
ATOM 10645 C CA  . GLU D 1 271 ? -8.773  -51.799 20.511  1.00 122.90 ? 271 GLU D CA  1 
ATOM 10646 C C   . GLU D 1 271 ? -7.435  -52.522 20.618  1.00 116.90 ? 271 GLU D C   1 
ATOM 10647 O O   . GLU D 1 271 ? -7.193  -53.522 19.925  1.00 114.41 ? 271 GLU D O   1 
ATOM 10648 C CB  . GLU D 1 271 ? -8.628  -50.519 19.686  1.00 127.87 ? 271 GLU D CB  1 
ATOM 10649 C CG  . GLU D 1 271 ? -9.701  -50.349 18.624  1.00 135.72 ? 271 GLU D CG  1 
ATOM 10650 C CD  . GLU D 1 271 ? -9.595  -51.393 17.529  1.00 135.51 ? 271 GLU D CD  1 
ATOM 10651 O OE1 . GLU D 1 271 ? -8.472  -51.625 17.038  1.00 131.98 ? 271 GLU D OE1 1 
ATOM 10652 O OE2 . GLU D 1 271 ? -10.634 -51.985 17.168  1.00 133.91 ? 271 GLU D OE2 1 
ATOM 10653 N N   . GLU D 1 272 ? -6.543  -52.022 21.480  1.00 112.47 ? 272 GLU D N   1 
ATOM 10654 C CA  . GLU D 1 272 ? -5.198  -52.575 21.578  1.00 111.04 ? 272 GLU D CA  1 
ATOM 10655 C C   . GLU D 1 272 ? -5.195  -54.004 22.106  1.00 109.53 ? 272 GLU D C   1 
ATOM 10656 O O   . GLU D 1 272 ? -4.235  -54.739 21.850  1.00 105.94 ? 272 GLU D O   1 
ATOM 10657 C CB  . GLU D 1 272 ? -4.327  -51.691 22.474  1.00 114.35 ? 272 GLU D CB  1 
ATOM 10658 C CG  . GLU D 1 272 ? -4.205  -50.241 22.020  1.00 117.48 ? 272 GLU D CG  1 
ATOM 10659 C CD  . GLU D 1 272 ? -3.118  -50.027 20.978  1.00 111.12 ? 272 GLU D CD  1 
ATOM 10660 O OE1 . GLU D 1 272 ? -2.648  -51.018 20.380  1.00 112.11 ? 272 GLU D OE1 1 
ATOM 10661 O OE2 . GLU D 1 272 ? -2.728  -48.859 20.760  1.00 110.03 ? 272 GLU D OE2 1 
ATOM 10662 N N   . VAL D 1 273 ? -6.233  -54.412 22.834  1.00 114.71 ? 273 VAL D N   1 
ATOM 10663 C CA  . VAL D 1 273 ? -6.286  -55.770 23.364  1.00 118.59 ? 273 VAL D CA  1 
ATOM 10664 C C   . VAL D 1 273 ? -7.070  -56.656 22.405  1.00 111.98 ? 273 VAL D C   1 
ATOM 10665 O O   . VAL D 1 273 ? -6.755  -57.840 22.247  1.00 107.34 ? 273 VAL D O   1 
ATOM 10666 C CB  . VAL D 1 273 ? -6.882  -55.803 24.787  1.00 117.58 ? 273 VAL D CB  1 
ATOM 10667 C CG1 . VAL D 1 273 ? -6.129  -54.844 25.698  1.00 115.41 ? 273 VAL D CG1 1 
ATOM 10668 C CG2 . VAL D 1 273 ? -8.369  -55.475 24.772  1.00 114.14 ? 273 VAL D CG2 1 
ATOM 10669 N N   . ALA D 1 274 ? -8.058  -56.084 21.709  1.00 115.86 ? 274 ALA D N   1 
ATOM 10670 C CA  . ALA D 1 274 ? -8.837  -56.870 20.760  1.00 112.90 ? 274 ALA D CA  1 
ATOM 10671 C C   . ALA D 1 274 ? -7.986  -57.282 19.565  1.00 111.33 ? 274 ALA D C   1 
ATOM 10672 O O   . ALA D 1 274 ? -7.962  -58.458 19.180  1.00 112.07 ? 274 ALA D O   1 
ATOM 10673 C CB  . ALA D 1 274 ? -10.064 -56.083 20.306  1.00 112.08 ? 274 ALA D CB  1 
ATOM 10674 N N   . ILE D 1 275 ? -7.274  -56.326 18.962  1.00 106.12 ? 275 ILE D N   1 
ATOM 10675 C CA  . ILE D 1 275 ? -6.423  -56.678 17.829  1.00 111.38 ? 275 ILE D CA  1 
ATOM 10676 C C   . ILE D 1 275 ? -5.232  -57.511 18.294  1.00 110.95 ? 275 ILE D C   1 
ATOM 10677 O O   . ILE D 1 275 ? -4.732  -58.364 17.549  1.00 112.59 ? 275 ILE D O   1 
ATOM 10678 C CB  . ILE D 1 275 ? -5.987  -55.410 17.074  1.00 117.08 ? 275 ILE D CB  1 
ATOM 10679 C CG1 . ILE D 1 275 ? -7.216  -54.610 16.645  1.00 119.83 ? 275 ILE D CG1 1 
ATOM 10680 C CG2 . ILE D 1 275 ? -5.152  -55.767 15.854  1.00 113.68 ? 275 ILE D CG2 1 
ATOM 10681 C CD1 . ILE D 1 275 ? -8.203  -55.407 15.811  1.00 121.33 ? 275 ILE D CD1 1 
ATOM 10682 N N   . GLY D 1 276 ? -4.769  -57.297 19.529  1.00 107.22 ? 276 GLY D N   1 
ATOM 10683 C CA  . GLY D 1 276 ? -3.720  -58.142 20.073  1.00 103.32 ? 276 GLY D CA  1 
ATOM 10684 C C   . GLY D 1 276 ? -4.160  -59.581 20.260  1.00 102.61 ? 276 GLY D C   1 
ATOM 10685 O O   . GLY D 1 276 ? -3.357  -60.507 20.102  1.00 99.31  ? 276 GLY D O   1 
ATOM 10686 N N   . LEU D 1 277 ? -5.430  -59.794 20.607  1.00 108.49 ? 277 LEU D N   1 
ATOM 10687 C CA  . LEU D 1 277 ? -5.976  -61.143 20.672  1.00 107.56 ? 277 LEU D CA  1 
ATOM 10688 C C   . LEU D 1 277 ? -6.236  -61.715 19.286  1.00 102.54 ? 277 LEU D C   1 
ATOM 10689 O O   . LEU D 1 277 ? -6.174  -62.938 19.104  1.00 102.93 ? 277 LEU D O   1 
ATOM 10690 C CB  . LEU D 1 277 ? -7.270  -61.151 21.488  1.00 101.69 ? 277 LEU D CB  1 
ATOM 10691 C CG  . LEU D 1 277 ? -7.127  -60.996 23.003  1.00 98.73  ? 277 LEU D CG  1 
ATOM 10692 C CD1 . LEU D 1 277 ? -8.486  -60.793 23.649  1.00 87.85  ? 277 LEU D CD1 1 
ATOM 10693 C CD2 . LEU D 1 277 ? -6.431  -62.209 23.594  1.00 102.65 ? 277 LEU D CD2 1 
ATOM 10694 N N   . GLU D 1 278 ? -6.529  -60.860 18.302  1.00 103.95 ? 278 GLU D N   1 
ATOM 10695 C CA  . GLU D 1 278 ? -6.754  -61.355 16.946  1.00 106.61 ? 278 GLU D CA  1 
ATOM 10696 C C   . GLU D 1 278 ? -5.472  -61.921 16.348  1.00 106.20 ? 278 GLU D C   1 
ATOM 10697 O O   . GLU D 1 278 ? -5.461  -63.044 15.830  1.00 104.69 ? 278 GLU D O   1 
ATOM 10698 C CB  . GLU D 1 278 ? -7.315  -60.243 16.056  1.00 108.82 ? 278 GLU D CB  1 
ATOM 10699 C CG  . GLU D 1 278 ? -7.558  -60.685 14.617  1.00 118.55 ? 278 GLU D CG  1 
ATOM 10700 C CD  . GLU D 1 278 ? -8.177  -59.595 13.762  1.00 122.77 ? 278 GLU D CD  1 
ATOM 10701 O OE1 . GLU D 1 278 ? -8.440  -58.495 14.291  1.00 119.71 ? 278 GLU D OE1 1 
ATOM 10702 O OE2 . GLU D 1 278 ? -8.405  -59.843 12.559  1.00 124.97 ? 278 GLU D OE2 1 
ATOM 10703 N N   . ILE D 1 279 ? -4.374  -61.158 16.409  1.00 106.10 ? 279 ILE D N   1 
ATOM 10704 C CA  . ILE D 1 279 ? -3.110  -61.610 15.829  1.00 102.67 ? 279 ILE D CA  1 
ATOM 10705 C C   . ILE D 1 279 ? -2.383  -62.610 16.712  1.00 100.73 ? 279 ILE D C   1 
ATOM 10706 O O   . ILE D 1 279 ? -1.323  -63.113 16.315  1.00 102.15 ? 279 ILE D O   1 
ATOM 10707 C CB  . ILE D 1 279 ? -2.171  -60.423 15.532  1.00 101.41 ? 279 ILE D CB  1 
ATOM 10708 C CG1 . ILE D 1 279 ? -1.719  -59.753 16.829  1.00 101.79 ? 279 ILE D CG1 1 
ATOM 10709 C CG2 . ILE D 1 279 ? -2.862  -59.415 14.628  1.00 106.22 ? 279 ILE D CG2 1 
ATOM 10710 C CD1 . ILE D 1 279 ? -0.678  -58.675 16.618  1.00 102.23 ? 279 ILE D CD1 1 
ATOM 10711 N N   . SER D 1 280 ? -2.917  -62.917 17.897  1.00 102.09 ? 280 SER D N   1 
ATOM 10712 C CA  . SER D 1 280 ? -2.316  -63.945 18.739  1.00 103.36 ? 280 SER D CA  1 
ATOM 10713 C C   . SER D 1 280 ? -2.520  -65.344 18.175  1.00 104.17 ? 280 SER D C   1 
ATOM 10714 O O   . SER D 1 280 ? -1.753  -66.250 18.513  1.00 106.52 ? 280 SER D O   1 
ATOM 10715 C CB  . SER D 1 280 ? -2.893  -63.866 20.154  1.00 102.98 ? 280 SER D CB  1 
ATOM 10716 O OG  . SER D 1 280 ? -2.597  -62.617 20.755  1.00 108.19 ? 280 SER D OG  1 
ATOM 10717 N N   . THR D 1 281 ? -3.532  -65.530 17.320  1.00 95.43  ? 281 THR D N   1 
ATOM 10718 C CA  . THR D 1 281 ? -3.819  -66.811 16.668  1.00 95.87  ? 281 THR D CA  1 
ATOM 10719 C C   . THR D 1 281 ? -3.980  -67.936 17.693  1.00 92.29  ? 281 THR D C   1 
ATOM 10720 O O   . THR D 1 281 ? -3.388  -69.010 17.571  1.00 96.95  ? 281 THR D O   1 
ATOM 10721 C CB  . THR D 1 281 ? -2.744  -67.161 15.633  1.00 102.75 ? 281 THR D CB  1 
ATOM 10722 O OG1 . THR D 1 281 ? -1.512  -67.473 16.297  1.00 101.81 ? 281 THR D OG1 1 
ATOM 10723 C CG2 . THR D 1 281 ? -2.521  -65.993 14.681  1.00 101.01 ? 281 THR D CG2 1 
ATOM 10724 N N   . VAL D 1 282 ? -4.798  -67.681 18.714  1.00 87.70  ? 282 VAL D N   1 
ATOM 10725 C CA  . VAL D 1 282 ? -5.081  -68.669 19.745  1.00 92.86  ? 282 VAL D CA  1 
ATOM 10726 C C   . VAL D 1 282 ? -6.504  -68.457 20.238  1.00 86.35  ? 282 VAL D C   1 
ATOM 10727 O O   . VAL D 1 282 ? -7.022  -67.335 20.235  1.00 84.55  ? 282 VAL D O   1 
ATOM 10728 C CB  . VAL D 1 282 ? -4.059  -68.594 20.906  1.00 92.77  ? 282 VAL D CB  1 
ATOM 10729 C CG1 . VAL D 1 282 ? -4.286  -67.353 21.757  1.00 85.86  ? 282 VAL D CG1 1 
ATOM 10730 C CG2 . VAL D 1 282 ? -4.107  -69.859 21.753  1.00 85.88  ? 282 VAL D CG2 1 
ATOM 10731 N N   . ASN D 1 283 ? -7.148  -69.550 20.643  1.00 81.80  ? 283 ASN D N   1 
ATOM 10732 C CA  . ASN D 1 283 ? -8.506  -69.478 21.159  1.00 86.24  ? 283 ASN D CA  1 
ATOM 10733 C C   . ASN D 1 283 ? -8.542  -68.665 22.448  1.00 85.78  ? 283 ASN D C   1 
ATOM 10734 O O   . ASN D 1 283 ? -7.605  -68.688 23.247  1.00 93.94  ? 283 ASN D O   1 
ATOM 10735 C CB  . ASN D 1 283 ? -9.052  -70.883 21.416  1.00 92.66  ? 283 ASN D CB  1 
ATOM 10736 C CG  . ASN D 1 283 ? -8.818  -71.819 20.249  1.00 96.23  ? 283 ASN D CG  1 
ATOM 10737 O OD1 . ASN D 1 283 ? -8.936  -71.423 19.089  1.00 87.88  ? 283 ASN D OD1 1 
ATOM 10738 N ND2 . ASN D 1 283 ? -8.479  -73.067 20.552  1.00 96.80  ? 283 ASN D ND2 1 
ATOM 10739 N N   . PHE D 1 284 ? -9.643  -67.951 22.657  1.00 87.10  ? 284 PHE D N   1 
ATOM 10740 C CA  . PHE D 1 284 ? -9.751  -67.108 23.838  1.00 83.51  ? 284 PHE D CA  1 
ATOM 10741 C C   . PHE D 1 284 ? -11.209 -66.955 24.243  1.00 86.86  ? 284 PHE D C   1 
ATOM 10742 O O   . PHE D 1 284 ? -12.121 -67.075 23.419  1.00 92.63  ? 284 PHE D O   1 
ATOM 10743 C CB  . PHE D 1 284 ? -9.124  -65.726 23.603  1.00 80.16  ? 284 PHE D CB  1 
ATOM 10744 C CG  . PHE D 1 284 ? -9.889  -64.869 22.636  1.00 87.47  ? 284 PHE D CG  1 
ATOM 10745 C CD1 . PHE D 1 284 ? -9.684  -64.988 21.273  1.00 89.50  ? 284 PHE D CD1 1 
ATOM 10746 C CD2 . PHE D 1 284 ? -10.811 -63.940 23.091  1.00 92.46  ? 284 PHE D CD2 1 
ATOM 10747 C CE1 . PHE D 1 284 ? -10.388 -64.204 20.382  1.00 92.40  ? 284 PHE D CE1 1 
ATOM 10748 C CE2 . PHE D 1 284 ? -11.518 -63.153 22.205  1.00 93.62  ? 284 PHE D CE2 1 
ATOM 10749 C CZ  . PHE D 1 284 ? -11.306 -63.283 20.849  1.00 88.62  ? 284 PHE D CZ  1 
ATOM 10750 N N   . ILE D 1 285 ? -11.410 -66.697 25.529  1.00 77.47  ? 285 ILE D N   1 
ATOM 10751 C CA  . ILE D 1 285 ? -12.691 -66.267 26.074  1.00 79.07  ? 285 ILE D CA  1 
ATOM 10752 C C   . ILE D 1 285 ? -12.430 -64.932 26.759  1.00 85.46  ? 285 ILE D C   1 
ATOM 10753 O O   . ILE D 1 285 ? -11.922 -64.889 27.884  1.00 83.59  ? 285 ILE D O   1 
ATOM 10754 C CB  . ILE D 1 285 ? -13.291 -67.288 27.045  1.00 80.90  ? 285 ILE D CB  1 
ATOM 10755 C CG1 . ILE D 1 285 ? -13.472 -68.637 26.354  1.00 74.70  ? 285 ILE D CG1 1 
ATOM 10756 C CG2 . ILE D 1 285 ? -14.624 -66.784 27.583  1.00 77.61  ? 285 ILE D CG2 1 
ATOM 10757 C CD1 . ILE D 1 285 ? -14.164 -69.673 27.212  1.00 76.77  ? 285 ILE D CD1 1 
ATOM 10758 N N   . TRP D 1 286 ? -12.750 -63.839 26.074  1.00 88.94  ? 286 TRP D N   1 
ATOM 10759 C CA  . TRP D 1 286 ? -12.500 -62.489 26.572  1.00 92.00  ? 286 TRP D CA  1 
ATOM 10760 C C   . TRP D 1 286 ? -13.808 -61.942 27.131  1.00 96.32  ? 286 TRP D C   1 
ATOM 10761 O O   . TRP D 1 286 ? -14.672 -61.483 26.385  1.00 106.25 ? 286 TRP D O   1 
ATOM 10762 C CB  . TRP D 1 286 ? -11.949 -61.601 25.463  1.00 99.15  ? 286 TRP D CB  1 
ATOM 10763 C CG  . TRP D 1 286 ? -11.851 -60.150 25.817  1.00 104.10 ? 286 TRP D CG  1 
ATOM 10764 C CD1 . TRP D 1 286 ? -11.682 -59.614 27.063  1.00 103.85 ? 286 TRP D CD1 1 
ATOM 10765 C CD2 . TRP D 1 286 ? -11.927 -59.044 24.912  1.00 106.27 ? 286 TRP D CD2 1 
ATOM 10766 N NE1 . TRP D 1 286 ? -11.645 -58.243 26.988  1.00 109.07 ? 286 TRP D NE1 1 
ATOM 10767 C CE2 . TRP D 1 286 ? -11.792 -57.868 25.678  1.00 108.41 ? 286 TRP D CE2 1 
ATOM 10768 C CE3 . TRP D 1 286 ? -12.092 -58.932 23.529  1.00 113.22 ? 286 TRP D CE3 1 
ATOM 10769 C CZ2 . TRP D 1 286 ? -11.819 -56.598 25.104  1.00 116.47 ? 286 TRP D CZ2 1 
ATOM 10770 C CZ3 . TRP D 1 286 ? -12.119 -57.670 22.963  1.00 118.81 ? 286 TRP D CZ3 1 
ATOM 10771 C CH2 . TRP D 1 286 ? -11.982 -56.520 23.749  1.00 120.38 ? 286 TRP D CH2 1 
ATOM 10772 N N   . ALA D 1 287 ? -13.946 -61.987 28.455  1.00 92.66  ? 287 ALA D N   1 
ATOM 10773 C CA  . ALA D 1 287 ? -15.131 -61.478 29.133  1.00 93.90  ? 287 ALA D CA  1 
ATOM 10774 C C   . ALA D 1 287 ? -14.924 -59.997 29.421  1.00 104.40 ? 287 ALA D C   1 
ATOM 10775 O O   . ALA D 1 287 ? -14.075 -59.630 30.241  1.00 100.76 ? 287 ALA D O   1 
ATOM 10776 C CB  . ALA D 1 287 ? -15.396 -62.259 30.415  1.00 79.49  ? 287 ALA D CB  1 
ATOM 10777 N N   . VAL D 1 288 ? -15.655 -59.158 28.680  1.00 107.89 ? 288 VAL D N   1 
ATOM 10778 C CA  . VAL D 1 288 ? -15.476 -57.679 28.751  1.00 109.81 ? 288 VAL D CA  1 
ATOM 10779 C C   . VAL D 1 288 ? -16.410 -57.078 29.801  1.00 103.15 ? 288 VAL D C   1 
ATOM 10780 O O   . VAL D 1 288 ? -17.047 -57.860 30.491  1.00 103.98 ? 288 VAL D O   1 
ATOM 10781 C CB  . VAL D 1 288 ? -15.648 -57.065 27.350  1.00 118.29 ? 288 VAL D CB  1 
ATOM 10782 C CG1 . VAL D 1 288 ? -17.101 -56.851 26.954  1.00 119.65 ? 288 VAL D CG1 1 
ATOM 10783 C CG2 . VAL D 1 288 ? -14.826 -55.804 27.151  1.00 113.42 ? 288 VAL D CG2 1 
ATOM 10784 N N   . PHE D 1 303 ? -11.170 -58.333 13.984  1.00 126.16 ? 303 PHE D N   1 
ATOM 10785 C CA  . PHE D 1 303 ? -12.001 -58.689 15.161  1.00 126.33 ? 303 PHE D CA  1 
ATOM 10786 C C   . PHE D 1 303 ? -13.466 -58.473 14.803  1.00 125.78 ? 303 PHE D C   1 
ATOM 10787 O O   . PHE D 1 303 ? -14.102 -59.449 14.390  1.00 124.03 ? 303 PHE D O   1 
ATOM 10788 C CB  . PHE D 1 303 ? -11.615 -57.831 16.367  1.00 126.41 ? 303 PHE D CB  1 
ATOM 10789 C CG  . PHE D 1 303 ? -11.761 -58.516 17.699  1.00 122.98 ? 303 PHE D CG  1 
ATOM 10790 C CD1 . PHE D 1 303 ? -10.829 -59.450 18.118  1.00 122.22 ? 303 PHE D CD1 1 
ATOM 10791 C CD2 . PHE D 1 303 ? -12.832 -58.230 18.526  1.00 115.41 ? 303 PHE D CD2 1 
ATOM 10792 C CE1 . PHE D 1 303 ? -10.964 -60.080 19.341  1.00 119.20 ? 303 PHE D CE1 1 
ATOM 10793 C CE2 . PHE D 1 303 ? -12.967 -58.865 19.749  1.00 111.08 ? 303 PHE D CE2 1 
ATOM 10794 C CZ  . PHE D 1 303 ? -12.034 -59.789 20.153  1.00 115.84 ? 303 PHE D CZ  1 
ATOM 10795 N N   . VAL D 1 304 ? -13.972 -57.247 14.973  1.00 130.73 ? 304 VAL D N   1 
ATOM 10796 C CA  . VAL D 1 304 ? -15.399 -56.904 14.678  1.00 127.30 ? 304 VAL D CA  1 
ATOM 10797 C C   . VAL D 1 304 ? -16.347 -58.021 15.160  1.00 128.01 ? 304 VAL D C   1 
ATOM 10798 O O   . VAL D 1 304 ? -17.448 -58.147 14.584  1.00 129.65 ? 304 VAL D O   1 
ATOM 10799 C CB  . VAL D 1 304 ? -15.594 -56.441 13.216  1.00 119.05 ? 304 VAL D CB  1 
ATOM 10800 C CG1 . VAL D 1 304 ? -15.716 -57.577 12.212  1.00 124.62 ? 304 VAL D CG1 1 
ATOM 10801 C CG2 . VAL D 1 304 ? -16.728 -55.438 13.065  1.00 113.05 ? 304 VAL D CG2 1 
ATOM 10802 N N   . GLN D 1 305 ? -15.964 -58.778 16.201  1.00 126.26 ? 305 GLN D N   1 
ATOM 10803 C CA  . GLN D 1 305 ? -16.792 -59.877 16.779  1.00 125.92 ? 305 GLN D CA  1 
ATOM 10804 C C   . GLN D 1 305 ? -17.049 -61.010 15.780  1.00 120.62 ? 305 GLN D C   1 
ATOM 10805 O O   . GLN D 1 305 ? -17.439 -62.099 16.238  1.00 116.91 ? 305 GLN D O   1 
ATOM 10806 C CB  . GLN D 1 305 ? -18.054 -59.330 17.452  1.00 129.54 ? 305 GLN D CB  1 
ATOM 10807 C CG  . GLN D 1 305 ? -17.811 -58.494 18.702  1.00 127.64 ? 305 GLN D CG  1 
ATOM 10808 C CD  . GLN D 1 305 ? -19.087 -57.928 19.274  1.00 134.10 ? 305 GLN D CD  1 
ATOM 10809 O OE1 . GLN D 1 305 ? -20.078 -57.740 18.571  1.00 133.83 ? 305 GLN D OE1 1 
ATOM 10810 N NE2 . GLN D 1 305 ? -19.072 -57.645 20.565  1.00 137.83 ? 305 GLN D NE2 1 
ATOM 10811 N N   . ARG D 1 306 ? -16.788 -60.808 14.486  1.00 124.72 ? 306 ARG D N   1 
ATOM 10812 C CA  . ARG D 1 306 ? -17.144 -61.837 13.477  1.00 118.75 ? 306 ARG D CA  1 
ATOM 10813 C C   . ARG D 1 306 ? -15.888 -62.387 12.809  1.00 111.16 ? 306 ARG D C   1 
ATOM 10814 O O   . ARG D 1 306 ? -15.998 -63.412 12.128  1.00 107.62 ? 306 ARG D O   1 
ATOM 10815 C CB  . ARG D 1 306 ? -18.095 -61.236 12.440  1.00 119.79 ? 306 ARG D CB  1 
ATOM 10816 C CG  . ARG D 1 306 ? -19.473 -60.888 12.983  1.00 121.80 ? 306 ARG D CG  1 
ATOM 10817 C CD  . ARG D 1 306 ? -20.165 -62.069 13.637  1.00 124.71 ? 306 ARG D CD  1 
ATOM 10818 N NE  . ARG D 1 306 ? -21.313 -61.670 14.439  1.00 127.59 ? 306 ARG D NE  1 
ATOM 10819 C CZ  . ARG D 1 306 ? -21.856 -62.411 15.399  1.00 123.19 ? 306 ARG D CZ  1 
ATOM 10820 N NH1 . ARG D 1 306 ? -21.353 -63.601 15.682  1.00 118.44 ? 306 ARG D NH1 1 
ATOM 10821 N NH2 . ARG D 1 306 ? -22.900 -61.963 16.074  1.00 110.85 ? 306 ARG D NH2 1 
ATOM 10822 N N   . VAL D 1 307 ? -14.742 -61.723 12.996  1.00 110.02 ? 307 VAL D N   1 
ATOM 10823 C CA  . VAL D 1 307 ? -13.449 -62.243 12.459  1.00 112.35 ? 307 VAL D CA  1 
ATOM 10824 C C   . VAL D 1 307 ? -12.541 -62.549 13.656  1.00 121.87 ? 307 VAL D C   1 
ATOM 10825 O O   . VAL D 1 307 ? -11.352 -62.854 13.436  1.00 123.31 ? 307 VAL D O   1 
ATOM 10826 C CB  . VAL D 1 307 ? -12.784 -61.258 11.477  1.00 117.74 ? 307 VAL D CB  1 
ATOM 10827 C CG1 . VAL D 1 307 ? -11.413 -61.742 11.031  1.00 119.17 ? 307 VAL D CG1 1 
ATOM 10828 C CG2 . VAL D 1 307 ? -13.661 -60.980 10.267  1.00 127.79 ? 307 VAL D CG2 1 
ATOM 10829 N N   . GLY D 1 308 ? -13.149 -62.742 14.830  1.00 119.83 ? 308 GLY D N   1 
ATOM 10830 C CA  . GLY D 1 308 ? -12.362 -63.151 16.008  1.00 108.81 ? 308 GLY D CA  1 
ATOM 10831 C C   . GLY D 1 308 ? -11.808 -64.541 15.790  1.00 109.93 ? 308 GLY D C   1 
ATOM 10832 O O   . GLY D 1 308 ? -12.616 -65.431 15.487  1.00 103.68 ? 308 GLY D O   1 
ATOM 10833 N N   . ASP D 1 309 ? -10.484 -64.718 15.904  1.00 109.72 ? 309 ASP D N   1 
ATOM 10834 C CA  . ASP D 1 309 ? -9.832  -66.036 15.671  1.00 111.46 ? 309 ASP D CA  1 
ATOM 10835 C C   . ASP D 1 309 ? -10.281 -67.009 16.750  1.00 111.06 ? 309 ASP D C   1 
ATOM 10836 O O   . ASP D 1 309 ? -9.508  -67.226 17.691  1.00 112.54 ? 309 ASP D O   1 
ATOM 10837 C CB  . ASP D 1 309 ? -8.306  -65.941 15.656  1.00 108.17 ? 309 ASP D CB  1 
ATOM 10838 C CG  . ASP D 1 309 ? -7.631  -67.112 14.965  1.00 112.27 ? 309 ASP D CG  1 
ATOM 10839 O OD1 . ASP D 1 309 ? -7.532  -67.082 13.725  1.00 126.09 ? 309 ASP D OD1 1 
ATOM 10840 O OD2 . ASP D 1 309 ? -7.207  -68.044 15.672  1.00 102.98 ? 309 ASP D OD2 1 
ATOM 10841 N N   . ARG D 1 310 ? -11.494 -67.539 16.623  1.00 106.09 ? 310 ARG D N   1 
ATOM 10842 C CA  . ARG D 1 310 ? -12.002 -68.546 17.582  1.00 99.21  ? 310 ARG D CA  1 
ATOM 10843 C C   . ARG D 1 310 ? -12.013 -67.965 18.994  1.00 96.70  ? 310 ARG D C   1 
ATOM 10844 O O   . ARG D 1 310 ? -11.163 -68.355 19.800  1.00 94.66  ? 310 ARG D O   1 
ATOM 10845 C CB  . ARG D 1 310 ? -11.206 -69.840 17.418  1.00 99.39  ? 310 ARG D CB  1 
ATOM 10846 C CG  . ARG D 1 310 ? -11.369 -70.492 16.052  1.00 93.16  ? 310 ARG D CG  1 
ATOM 10847 C CD  . ARG D 1 310 ? -12.823 -70.764 15.718  1.00 95.04  ? 310 ARG D CD  1 
ATOM 10848 N NE  . ARG D 1 310 ? -13.376 -69.813 14.765  1.00 93.70  ? 310 ARG D NE  1 
ATOM 10849 C CZ  . ARG D 1 310 ? -14.438 -69.049 14.995  1.00 92.92  ? 310 ARG D CZ  1 
ATOM 10850 N NH1 . ARG D 1 310 ? -15.069 -69.122 16.154  1.00 86.93  ? 310 ARG D NH1 1 
ATOM 10851 N NH2 . ARG D 1 310 ? -14.866 -68.214 14.067  1.00 95.78  ? 310 ARG D NH2 1 
ATOM 10852 N N   . GLY D 1 311 ? -12.965 -67.071 19.267  1.00 93.27  ? 311 GLY D N   1 
ATOM 10853 C CA  . GLY D 1 311 ? -13.094 -66.480 20.610  1.00 91.55  ? 311 GLY D CA  1 
ATOM 10854 C C   . GLY D 1 311 ? -14.540 -66.238 20.981  1.00 86.78  ? 311 GLY D C   1 
ATOM 10855 O O   . GLY D 1 311 ? -15.404 -66.436 20.117  1.00 89.59  ? 311 GLY D O   1 
ATOM 10856 N N   . LEU D 1 312 ? -14.791 -65.816 22.221  1.00 85.04  ? 312 LEU D N   1 
ATOM 10857 C CA  . LEU D 1 312 ? -16.171 -65.518 22.682  1.00 93.63  ? 312 LEU D CA  1 
ATOM 10858 C C   . LEU D 1 312 ? -16.140 -64.332 23.646  1.00 97.88  ? 312 LEU D C   1 
ATOM 10859 O O   . LEU D 1 312 ? -15.462 -64.434 24.669  1.00 102.47 ? 312 LEU D O   1 
ATOM 10860 C CB  . LEU D 1 312 ? -16.737 -66.764 23.366  1.00 91.45  ? 312 LEU D CB  1 
ATOM 10861 C CG  . LEU D 1 312 ? -18.176 -66.670 23.869  1.00 97.29  ? 312 LEU D CG  1 
ATOM 10862 C CD1 . LEU D 1 312 ? -19.086 -66.060 22.817  1.00 100.94 ? 312 LEU D CD1 1 
ATOM 10863 C CD2 . LEU D 1 312 ? -18.686 -68.042 24.275  1.00 99.95  ? 312 LEU D CD2 1 
ATOM 10864 N N   . VAL D 1 313 ? -16.859 -63.257 23.326  1.00 93.45  ? 313 VAL D N   1 
ATOM 10865 C CA  . VAL D 1 313 ? -16.926 -62.101 24.213  1.00 99.51  ? 313 VAL D CA  1 
ATOM 10866 C C   . VAL D 1 313 ? -18.201 -62.186 25.037  1.00 103.89 ? 313 VAL D C   1 
ATOM 10867 O O   . VAL D 1 313 ? -19.264 -62.571 24.530  1.00 103.29 ? 313 VAL D O   1 
ATOM 10868 C CB  . VAL D 1 313 ? -16.861 -60.779 23.421  1.00 104.21 ? 313 VAL D CB  1 
ATOM 10869 C CG1 . VAL D 1 313 ? -15.490 -60.611 22.786  1.00 102.99 ? 313 VAL D CG1 1 
ATOM 10870 C CG2 . VAL D 1 313 ? -17.950 -60.733 22.358  1.00 106.06 ? 313 VAL D CG2 1 
ATOM 10871 N N   . VAL D 1 314 ? -18.098 -61.840 26.317  1.00 107.99 ? 314 VAL D N   1 
ATOM 10872 C CA  . VAL D 1 314 ? -19.217 -61.896 27.248  1.00 104.10 ? 314 VAL D CA  1 
ATOM 10873 C C   . VAL D 1 314 ? -19.407 -60.513 27.860  1.00 106.48 ? 314 VAL D C   1 
ATOM 10874 O O   . VAL D 1 314 ? -18.432 -59.789 28.090  1.00 104.53 ? 314 VAL D O   1 
ATOM 10875 C CB  . VAL D 1 314 ? -18.991 -62.955 28.350  1.00 104.81 ? 314 VAL D CB  1 
ATOM 10876 C CG1 . VAL D 1 314 ? -20.277 -63.206 29.126  1.00 99.65  ? 314 VAL D CG1 1 
ATOM 10877 C CG2 . VAL D 1 314 ? -18.466 -64.251 27.744  1.00 100.89 ? 314 VAL D CG2 1 
ATOM 10878 N N   . GLU D 1 315 ? -20.662 -60.153 28.122  1.00 107.39 ? 315 GLU D N   1 
ATOM 10879 C CA  . GLU D 1 315 ? -20.983 -58.843 28.676  1.00 115.49 ? 315 GLU D CA  1 
ATOM 10880 C C   . GLU D 1 315 ? -20.637 -58.762 30.156  1.00 122.43 ? 315 GLU D C   1 
ATOM 10881 O O   . GLU D 1 315 ? -19.684 -58.073 30.541  1.00 123.76 ? 315 GLU D O   1 
ATOM 10882 C CB  . GLU D 1 315 ? -22.465 -58.522 28.467  1.00 115.03 ? 315 GLU D CB  1 
ATOM 10883 C CG  . GLU D 1 315 ? -22.906 -57.199 29.077  1.00 122.84 ? 315 GLU D CG  1 
ATOM 10884 C CD  . GLU D 1 315 ? -24.024 -57.365 30.089  1.00 122.64 ? 315 GLU D CD  1 
ATOM 10885 O OE1 . GLU D 1 315 ? -24.683 -58.425 30.084  1.00 121.52 ? 315 GLU D OE1 1 
ATOM 10886 O OE2 . GLU D 1 315 ? -24.243 -56.433 30.894  1.00 117.93 ? 315 GLU D OE2 1 
ATOM 10887 N N   . GLY D 1 316 ? -21.399 -59.460 30.994  1.00 118.62 ? 316 GLY D N   1 
ATOM 10888 C CA  . GLY D 1 316 ? -21.249 -59.344 32.432  1.00 116.42 ? 316 GLY D CA  1 
ATOM 10889 C C   . GLY D 1 316 ? -20.436 -60.444 33.081  1.00 115.10 ? 316 GLY D C   1 
ATOM 10890 O O   . GLY D 1 316 ? -19.290 -60.690 32.694  1.00 114.33 ? 316 GLY D O   1 
ATOM 10891 N N   . TRP D 1 317 ? -21.020 -61.109 34.075  1.00 122.16 ? 317 TRP D N   1 
ATOM 10892 C CA  . TRP D 1 317 ? -20.294 -62.108 34.844  1.00 128.74 ? 317 TRP D CA  1 
ATOM 10893 C C   . TRP D 1 317 ? -19.974 -63.326 33.984  1.00 124.34 ? 317 TRP D C   1 
ATOM 10894 O O   . TRP D 1 317 ? -20.801 -63.788 33.193  1.00 111.38 ? 317 TRP D O   1 
ATOM 10895 C CB  . TRP D 1 317 ? -21.101 -62.528 36.073  1.00 129.60 ? 317 TRP D CB  1 
ATOM 10896 C CG  . TRP D 1 317 ? -21.332 -61.418 37.057  1.00 143.60 ? 317 TRP D CG  1 
ATOM 10897 C CD1 . TRP D 1 317 ? -20.380 -60.708 37.732  1.00 146.02 ? 317 TRP D CD1 1 
ATOM 10898 C CD2 . TRP D 1 317 ? -22.598 -60.896 37.490  1.00 142.44 ? 317 TRP D CD2 1 
ATOM 10899 N NE1 . TRP D 1 317 ? -20.971 -59.776 38.547  1.00 146.66 ? 317 TRP D NE1 1 
ATOM 10900 C CE2 . TRP D 1 317 ? -22.331 -59.871 38.418  1.00 148.22 ? 317 TRP D CE2 1 
ATOM 10901 C CE3 . TRP D 1 317 ? -23.927 -61.197 37.176  1.00 129.59 ? 317 TRP D CE3 1 
ATOM 10902 C CZ2 . TRP D 1 317 ? -23.345 -59.144 39.038  1.00 141.81 ? 317 TRP D CZ2 1 
ATOM 10903 C CZ3 . TRP D 1 317 ? -24.933 -60.473 37.795  1.00 128.14 ? 317 TRP D CZ3 1 
ATOM 10904 C CH2 . TRP D 1 317 ? -24.637 -59.459 38.713  1.00 128.99 ? 317 TRP D CH2 1 
ATOM 10905 N N   . ALA D 1 318 ? -18.760 -63.847 34.151  1.00 127.77 ? 318 ALA D N   1 
ATOM 10906 C CA  . ALA D 1 318 ? -18.269 -64.996 33.415  1.00 118.79 ? 318 ALA D CA  1 
ATOM 10907 C C   . ALA D 1 318 ? -17.864 -66.106 34.378  1.00 114.56 ? 318 ALA D C   1 
ATOM 10908 O O   . ALA D 1 318 ? -17.489 -65.831 35.523  1.00 120.12 ? 318 ALA D O   1 
ATOM 10909 C CB  . ALA D 1 318 ? -17.070 -64.622 32.536  1.00 112.87 ? 318 ALA D CB  1 
ATOM 10910 N N   . PRO D 1 319 ? -17.928 -67.368 33.947  1.00 107.56 ? 319 PRO D N   1 
ATOM 10911 C CA  . PRO D 1 319 ? -17.512 -68.466 34.828  1.00 103.44 ? 319 PRO D CA  1 
ATOM 10912 C C   . PRO D 1 319 ? -16.005 -68.492 35.024  1.00 100.61 ? 319 PRO D C   1 
ATOM 10913 O O   . PRO D 1 319 ? -15.332 -69.401 34.533  1.00 95.10  ? 319 PRO D O   1 
ATOM 10914 C CB  . PRO D 1 319 ? -17.999 -69.722 34.090  1.00 103.89 ? 319 PRO D CB  1 
ATOM 10915 C CG  . PRO D 1 319 ? -18.904 -69.229 33.003  1.00 112.52 ? 319 PRO D CG  1 
ATOM 10916 C CD  . PRO D 1 319 ? -18.442 -67.859 32.662  1.00 114.55 ? 319 PRO D CD  1 
ATOM 10917 N N   . GLN D 1 320 ? -15.473 -67.500 35.741  1.00 105.09 ? 320 GLN D N   1 
ATOM 10918 C CA  . GLN D 1 320 ? -14.026 -67.375 35.889  1.00 98.49  ? 320 GLN D CA  1 
ATOM 10919 C C   . GLN D 1 320 ? -13.426 -68.628 36.514  1.00 95.48  ? 320 GLN D C   1 
ATOM 10920 O O   . GLN D 1 320 ? -12.497 -69.228 35.959  1.00 94.18  ? 320 GLN D O   1 
ATOM 10921 C CB  . GLN D 1 320 ? -13.695 -66.142 36.727  1.00 102.42 ? 320 GLN D CB  1 
ATOM 10922 C CG  . GLN D 1 320 ? -12.225 -65.770 36.743  1.00 84.54  ? 320 GLN D CG  1 
ATOM 10923 C CD  . GLN D 1 320 ? -11.950 -64.539 37.581  1.00 89.81  ? 320 GLN D CD  1 
ATOM 10924 O OE1 . GLN D 1 320 ? -12.580 -64.327 38.620  1.00 94.79  ? 320 GLN D OE1 1 
ATOM 10925 N NE2 . GLN D 1 320 ? -11.008 -63.714 37.131  1.00 91.06  ? 320 GLN D NE2 1 
ATOM 10926 N N   . ALA D 1 321 ? -13.953 -69.042 37.667  1.00 97.60  ? 321 ALA D N   1 
ATOM 10927 C CA  . ALA D 1 321 ? -13.450 -70.249 38.314  1.00 95.80  ? 321 ALA D CA  1 
ATOM 10928 C C   . ALA D 1 321 ? -13.697 -71.481 37.453  1.00 93.48  ? 321 ALA D C   1 
ATOM 10929 O O   . ALA D 1 321 ? -12.848 -72.379 37.383  1.00 92.96  ? 321 ALA D O   1 
ATOM 10930 C CB  . ALA D 1 321 ? -14.096 -70.418 39.688  1.00 104.16 ? 321 ALA D CB  1 
ATOM 10931 N N   . ARG D 1 322 ? -14.849 -71.540 36.782  1.00 97.86  ? 322 ARG D N   1 
ATOM 10932 C CA  . ARG D 1 322 ? -15.188 -72.700 35.964  1.00 101.05 ? 322 ARG D CA  1 
ATOM 10933 C C   . ARG D 1 322 ? -14.409 -72.731 34.657  1.00 97.36  ? 322 ARG D C   1 
ATOM 10934 O O   . ARG D 1 322 ? -14.190 -73.812 34.099  1.00 94.35  ? 322 ARG D O   1 
ATOM 10935 C CB  . ARG D 1 322 ? -16.693 -72.720 35.688  1.00 109.43 ? 322 ARG D CB  1 
ATOM 10936 C CG  . ARG D 1 322 ? -17.543 -72.417 36.917  1.00 109.53 ? 322 ARG D CG  1 
ATOM 10937 C CD  . ARG D 1 322 ? -19.033 -72.579 36.644  1.00 103.22 ? 322 ARG D CD  1 
ATOM 10938 N NE  . ARG D 1 322 ? -19.514 -73.913 36.980  1.00 103.61 ? 322 ARG D NE  1 
ATOM 10939 C CZ  . ARG D 1 322 ? -19.557 -74.935 36.136  1.00 111.95 ? 322 ARG D CZ  1 
ATOM 10940 N NH1 . ARG D 1 322 ? -19.155 -74.814 34.881  1.00 108.69 ? 322 ARG D NH1 1 
ATOM 10941 N NH2 . ARG D 1 322 ? -20.018 -76.110 36.559  1.00 118.92 ? 322 ARG D NH2 1 
ATOM 10942 N N   . ILE D 1 323 ? -13.981 -71.571 34.152  1.00 97.33  ? 323 ILE D N   1 
ATOM 10943 C CA  . ILE D 1 323 ? -13.151 -71.552 32.954  1.00 92.20  ? 323 ILE D CA  1 
ATOM 10944 C C   . ILE D 1 323 ? -11.704 -71.880 33.297  1.00 92.04  ? 323 ILE D C   1 
ATOM 10945 O O   . ILE D 1 323 ? -11.050 -72.664 32.599  1.00 92.78  ? 323 ILE D O   1 
ATOM 10946 C CB  . ILE D 1 323 ? -13.270 -70.194 32.237  1.00 93.03  ? 323 ILE D CB  1 
ATOM 10947 C CG1 . ILE D 1 323 ? -14.637 -70.066 31.567  1.00 90.97  ? 323 ILE D CG1 1 
ATOM 10948 C CG2 . ILE D 1 323 ? -12.160 -70.023 31.216  1.00 90.72  ? 323 ILE D CG2 1 
ATOM 10949 C CD1 . ILE D 1 323 ? -14.859 -68.731 30.902  1.00 89.77  ? 323 ILE D CD1 1 
ATOM 10950 N N   . LEU D 1 324 ? -11.179 -71.291 34.377  1.00 90.54  ? 324 LEU D N   1 
ATOM 10951 C CA  . LEU D 1 324 ? -9.821  -71.611 34.798  1.00 93.00  ? 324 LEU D CA  1 
ATOM 10952 C C   . LEU D 1 324 ? -9.698  -73.066 35.227  1.00 95.09  ? 324 LEU D C   1 
ATOM 10953 O O   . LEU D 1 324 ? -8.652  -73.692 35.017  1.00 95.95  ? 324 LEU D O   1 
ATOM 10954 C CB  . LEU D 1 324 ? -9.385  -70.680 35.929  1.00 83.71  ? 324 LEU D CB  1 
ATOM 10955 C CG  . LEU D 1 324 ? -9.255  -69.195 35.587  1.00 74.54  ? 324 LEU D CG  1 
ATOM 10956 C CD1 . LEU D 1 324 ? -8.776  -68.415 36.801  1.00 71.78  ? 324 LEU D CD1 1 
ATOM 10957 C CD2 . LEU D 1 324 ? -8.317  -68.990 34.407  1.00 75.01  ? 324 LEU D CD2 1 
ATOM 10958 N N   . GLY D 1 325 ? -10.757 -73.629 35.819  1.00 88.33  ? 325 GLY D N   1 
ATOM 10959 C CA  . GLY D 1 325 ? -10.738 -75.031 36.191  1.00 91.96  ? 325 GLY D CA  1 
ATOM 10960 C C   . GLY D 1 325 ? -10.938 -75.987 35.038  1.00 101.44 ? 325 GLY D C   1 
ATOM 10961 O O   . GLY D 1 325 ? -10.627 -77.174 35.172  1.00 109.31 ? 325 GLY D O   1 
ATOM 10962 N N   . HIS D 1 326 ? -11.435 -75.500 33.906  1.00 105.39 ? 326 HIS D N   1 
ATOM 10963 C CA  . HIS D 1 326 ? -11.621 -76.364 32.748  1.00 105.06 ? 326 HIS D CA  1 
ATOM 10964 C C   . HIS D 1 326 ? -10.273 -76.712 32.131  1.00 101.04 ? 326 HIS D C   1 
ATOM 10965 O O   . HIS D 1 326 ? -9.343  -75.901 32.125  1.00 95.59  ? 326 HIS D O   1 
ATOM 10966 C CB  . HIS D 1 326 ? -12.528 -75.688 31.718  1.00 95.33  ? 326 HIS D CB  1 
ATOM 10967 C CG  . HIS D 1 326 ? -13.040 -76.613 30.661  1.00 106.91 ? 326 HIS D CG  1 
ATOM 10968 N ND1 . HIS D 1 326 ? -12.425 -76.750 29.436  1.00 109.45 ? 326 HIS D ND1 1 
ATOM 10969 C CD2 . HIS D 1 326 ? -14.106 -77.448 30.644  1.00 108.34 ? 326 HIS D CD2 1 
ATOM 10970 C CE1 . HIS D 1 326 ? -13.090 -77.630 28.707  1.00 106.88 ? 326 HIS D CE1 1 
ATOM 10971 N NE2 . HIS D 1 326 ? -14.113 -78.068 29.417  1.00 107.32 ? 326 HIS D NE2 1 
ATOM 10972 N N   . SER D 1 327 ? -10.170 -77.936 31.610  1.00 103.25 ? 327 SER D N   1 
ATOM 10973 C CA  . SER D 1 327 ? -8.886  -78.425 31.119  1.00 103.04 ? 327 SER D CA  1 
ATOM 10974 C C   . SER D 1 327 ? -8.458  -77.753 29.821  1.00 99.18  ? 327 SER D C   1 
ATOM 10975 O O   . SER D 1 327 ? -7.279  -77.831 29.461  1.00 95.79  ? 327 SER D O   1 
ATOM 10976 C CB  . SER D 1 327 ? -8.942  -79.939 30.922  1.00 108.33 ? 327 SER D CB  1 
ATOM 10977 O OG  . SER D 1 327 ? -10.003 -80.304 30.056  1.00 110.27 ? 327 SER D OG  1 
ATOM 10978 N N   . SER D 1 328 ? -9.379  -77.102 29.109  1.00 102.30 ? 328 SER D N   1 
ATOM 10979 C CA  . SER D 1 328 ? -9.044  -76.467 27.839  1.00 102.29 ? 328 SER D CA  1 
ATOM 10980 C C   . SER D 1 328 ? -8.356  -75.120 28.007  1.00 97.04  ? 328 SER D C   1 
ATOM 10981 O O   . SER D 1 328 ? -7.851  -74.575 27.018  1.00 92.95  ? 328 SER D O   1 
ATOM 10982 C CB  . SER D 1 328 ? -10.304 -76.294 26.988  1.00 100.27 ? 328 SER D CB  1 
ATOM 10983 O OG  . SER D 1 328 ? -10.827 -77.548 26.594  1.00 104.40 ? 328 SER D OG  1 
ATOM 10984 N N   . THR D 1 329 ? -8.321  -74.572 29.216  1.00 91.97  ? 329 THR D N   1 
ATOM 10985 C CA  . THR D 1 329 ? -7.709  -73.275 29.453  1.00 92.56  ? 329 THR D CA  1 
ATOM 10986 C C   . THR D 1 329 ? -6.246  -73.454 29.838  1.00 93.98  ? 329 THR D C   1 
ATOM 10987 O O   . THR D 1 329 ? -5.917  -74.241 30.733  1.00 95.06  ? 329 THR D O   1 
ATOM 10988 C CB  . THR D 1 329 ? -8.456  -72.512 30.547  1.00 92.29  ? 329 THR D CB  1 
ATOM 10989 O OG1 . THR D 1 329 ? -9.863  -72.572 30.290  1.00 89.72  ? 329 THR D OG1 1 
ATOM 10990 C CG2 . THR D 1 329 ? -8.019  -71.057 30.572  1.00 85.88  ? 329 THR D CG2 1 
ATOM 10991 N N   . GLY D 1 330 ? -5.375  -72.728 29.148  1.00 85.24  ? 330 GLY D N   1 
ATOM 10992 C CA  . GLY D 1 330 ? -3.954  -72.759 29.426  1.00 77.36  ? 330 GLY D CA  1 
ATOM 10993 C C   . GLY D 1 330 ? -3.329  -71.379 29.489  1.00 81.36  ? 330 GLY D C   1 
ATOM 10994 O O   . GLY D 1 330 ? -2.104  -71.239 29.394  1.00 82.44  ? 330 GLY D O   1 
ATOM 10995 N N   . GLY D 1 331 ? -4.166  -70.353 29.650  1.00 78.69  ? 331 GLY D N   1 
ATOM 10996 C CA  . GLY D 1 331 ? -3.714  -68.976 29.733  1.00 67.15  ? 331 GLY D CA  1 
ATOM 10997 C C   . GLY D 1 331 ? -4.754  -68.049 30.332  1.00 67.32  ? 331 GLY D C   1 
ATOM 10998 O O   . GLY D 1 331 ? -5.957  -68.226 30.108  1.00 73.20  ? 331 GLY D O   1 
ATOM 10999 N N   . PHE D 1 332 ? -4.304  -67.054 31.100  1.00 62.25  ? 332 PHE D N   1 
ATOM 11000 C CA  . PHE D 1 332 ? -5.214  -66.137 31.796  1.00 68.30  ? 332 PHE D CA  1 
ATOM 11001 C C   . PHE D 1 332 ? -4.650  -64.723 31.692  1.00 71.18  ? 332 PHE D C   1 
ATOM 11002 O O   . PHE D 1 332 ? -3.773  -64.343 32.474  1.00 76.31  ? 332 PHE D O   1 
ATOM 11003 C CB  . PHE D 1 332 ? -5.406  -66.554 33.252  1.00 57.93  ? 332 PHE D CB  1 
ATOM 11004 C CG  . PHE D 1 332 ? -6.400  -65.708 34.029  1.00 62.88  ? 332 PHE D CG  1 
ATOM 11005 C CD1 . PHE D 1 332 ? -7.240  -64.800 33.397  1.00 63.78  ? 332 PHE D CD1 1 
ATOM 11006 C CD2 . PHE D 1 332 ? -6.483  -65.826 35.407  1.00 75.51  ? 332 PHE D CD2 1 
ATOM 11007 C CE1 . PHE D 1 332 ? -8.140  -64.026 34.132  1.00 74.21  ? 332 PHE D CE1 1 
ATOM 11008 C CE2 . PHE D 1 332 ? -7.381  -65.058 36.144  1.00 74.92  ? 332 PHE D CE2 1 
ATOM 11009 C CZ  . PHE D 1 332 ? -8.208  -64.161 35.507  1.00 69.51  ? 332 PHE D CZ  1 
ATOM 11010 N N   . VAL D 1 333 ? -5.165  -63.945 30.746  1.00 72.34  ? 333 VAL D N   1 
ATOM 11011 C CA  . VAL D 1 333 ? -4.825  -62.530 30.634  1.00 69.34  ? 333 VAL D CA  1 
ATOM 11012 C C   . VAL D 1 333 ? -5.620  -61.783 31.702  1.00 71.88  ? 333 VAL D C   1 
ATOM 11013 O O   . VAL D 1 333 ? -6.847  -61.691 31.620  1.00 69.95  ? 333 VAL D O   1 
ATOM 11014 C CB  . VAL D 1 333 ? -5.124  -61.980 29.236  1.00 73.65  ? 333 VAL D CB  1 
ATOM 11015 C CG1 . VAL D 1 333 ? -4.800  -60.494 29.169  1.00 69.30  ? 333 VAL D CG1 1 
ATOM 11016 C CG2 . VAL D 1 333 ? -4.332  -62.743 28.188  1.00 75.74  ? 333 VAL D CG2 1 
ATOM 11017 N N   . SER D 1 334 ? -4.926  -61.247 32.703  1.00 73.26  ? 334 SER D N   1 
ATOM 11018 C CA  . SER D 1 334 ? -5.594  -60.701 33.872  1.00 64.59  ? 334 SER D CA  1 
ATOM 11019 C C   . SER D 1 334 ? -5.017  -59.341 34.242  1.00 63.37  ? 334 SER D C   1 
ATOM 11020 O O   . SER D 1 334 ? -3.880  -59.008 33.904  1.00 67.79  ? 334 SER D O   1 
ATOM 11021 C CB  . SER D 1 334 ? -5.482  -61.652 35.071  1.00 61.11  ? 334 SER D CB  1 
ATOM 11022 O OG  . SER D 1 334 ? -5.988  -61.048 36.246  1.00 68.10  ? 334 SER D OG  1 
ATOM 11023 N N   . HIS D 1 335 ? -5.830  -58.557 34.949  1.00 61.75  ? 335 HIS D N   1 
ATOM 11024 C CA  . HIS D 1 335 ? -5.378  -57.294 35.520  1.00 68.80  ? 335 HIS D CA  1 
ATOM 11025 C C   . HIS D 1 335 ? -4.647  -57.482 36.840  1.00 68.76  ? 335 HIS D C   1 
ATOM 11026 O O   . HIS D 1 335 ? -4.292  -56.484 37.477  1.00 67.74  ? 335 HIS D O   1 
ATOM 11027 C CB  . HIS D 1 335 ? -6.565  -56.346 35.715  1.00 70.73  ? 335 HIS D CB  1 
ATOM 11028 C CG  . HIS D 1 335 ? -7.447  -56.704 36.873  1.00 75.73  ? 335 HIS D CG  1 
ATOM 11029 N ND1 . HIS D 1 335 ? -8.168  -57.878 36.925  1.00 70.51  ? 335 HIS D ND1 1 
ATOM 11030 C CD2 . HIS D 1 335 ? -7.732  -56.035 38.017  1.00 84.96  ? 335 HIS D CD2 1 
ATOM 11031 C CE1 . HIS D 1 335 ? -8.852  -57.921 38.055  1.00 71.21  ? 335 HIS D CE1 1 
ATOM 11032 N NE2 . HIS D 1 335 ? -8.608  -56.815 38.735  1.00 82.51  ? 335 HIS D NE2 1 
ATOM 11033 N N   . CYS D 1 336 ? -4.429  -58.732 37.261  1.00 70.76  ? 336 CYS D N   1 
ATOM 11034 C CA  . CYS D 1 336 ? -3.620  -59.070 38.435  1.00 68.10  ? 336 CYS D CA  1 
ATOM 11035 C C   . CYS D 1 336 ? -4.285  -58.623 39.738  1.00 66.97  ? 336 CYS D C   1 
ATOM 11036 O O   . CYS D 1 336 ? -3.660  -58.010 40.600  1.00 67.71  ? 336 CYS D O   1 
ATOM 11037 C CB  . CYS D 1 336 ? -2.203  -58.502 38.317  1.00 65.14  ? 336 CYS D CB  1 
ATOM 11038 S SG  . CYS D 1 336 ? -1.221  -59.296 37.045  1.00 56.44  ? 336 CYS D SG  1 
ATOM 11039 N N   . GLY D 1 337 ? -5.570  -58.937 39.871  1.00 70.56  ? 337 GLY D N   1 
ATOM 11040 C CA  . GLY D 1 337 ? -6.191  -58.908 41.178  1.00 61.94  ? 337 GLY D CA  1 
ATOM 11041 C C   . GLY D 1 337 ? -5.732  -60.086 42.016  1.00 55.71  ? 337 GLY D C   1 
ATOM 11042 O O   . GLY D 1 337 ? -5.385  -61.149 41.499  1.00 50.30  ? 337 GLY D O   1 
ATOM 11043 N N   . TRP D 1 338 ? -5.717  -59.894 43.334  1.00 62.14  ? 338 TRP D N   1 
ATOM 11044 C CA  . TRP D 1 338 ? -5.186  -60.934 44.210  1.00 53.35  ? 338 TRP D CA  1 
ATOM 11045 C C   . TRP D 1 338 ? -6.026  -62.201 44.134  1.00 52.75  ? 338 TRP D C   1 
ATOM 11046 O O   . TRP D 1 338 ? -5.489  -63.309 44.020  1.00 54.47  ? 338 TRP D O   1 
ATOM 11047 C CB  . TRP D 1 338 ? -5.092  -60.425 45.648  1.00 49.49  ? 338 TRP D CB  1 
ATOM 11048 C CG  . TRP D 1 338 ? -4.352  -61.362 46.555  1.00 55.28  ? 338 TRP D CG  1 
ATOM 11049 C CD1 . TRP D 1 338 ? -4.808  -61.907 47.718  1.00 52.05  ? 338 TRP D CD1 1 
ATOM 11050 C CD2 . TRP D 1 338 ? -3.026  -61.878 46.366  1.00 50.38  ? 338 TRP D CD2 1 
ATOM 11051 N NE1 . TRP D 1 338 ? -3.849  -62.717 48.272  1.00 50.94  ? 338 TRP D NE1 1 
ATOM 11052 C CE2 . TRP D 1 338 ? -2.746  -62.719 47.461  1.00 47.88  ? 338 TRP D CE2 1 
ATOM 11053 C CE3 . TRP D 1 338 ? -2.049  -61.704 45.378  1.00 59.96  ? 338 TRP D CE3 1 
ATOM 11054 C CZ2 . TRP D 1 338 ? -1.529  -63.385 47.596  1.00 57.14  ? 338 TRP D CZ2 1 
ATOM 11055 C CZ3 . TRP D 1 338 ? -0.845  -62.368 45.514  1.00 61.35  ? 338 TRP D CZ3 1 
ATOM 11056 C CH2 . TRP D 1 338 ? -0.595  -63.197 46.614  1.00 55.91  ? 338 TRP D CH2 1 
ATOM 11057 N N   . SER D 1 339 ? -7.352  -62.064 44.196  1.00 60.05  ? 339 SER D N   1 
ATOM 11058 C CA  . SER D 1 339 ? -8.210  -63.240 44.057  1.00 58.37  ? 339 SER D CA  1 
ATOM 11059 C C   . SER D 1 339 ? -8.076  -63.855 42.671  1.00 56.06  ? 339 SER D C   1 
ATOM 11060 O O   . SER D 1 339 ? -8.129  -65.081 42.520  1.00 65.17  ? 339 SER D O   1 
ATOM 11061 C CB  . SER D 1 339 ? -9.665  -62.870 44.346  1.00 63.62  ? 339 SER D CB  1 
ATOM 11062 O OG  . SER D 1 339 ? -9.836  -62.499 45.701  1.00 73.85  ? 339 SER D OG  1 
ATOM 11063 N N   . SER D 1 340 ? -7.880  -63.019 41.650  1.00 59.75  ? 340 SER D N   1 
ATOM 11064 C CA  . SER D 1 340 ? -7.710  -63.531 40.295  1.00 69.29  ? 340 SER D CA  1 
ATOM 11065 C C   . SER D 1 340 ? -6.439  -64.364 40.177  1.00 67.09  ? 340 SER D C   1 
ATOM 11066 O O   . SER D 1 340 ? -6.453  -65.459 39.601  1.00 61.07  ? 340 SER D O   1 
ATOM 11067 C CB  . SER D 1 340 ? -7.697  -62.373 39.300  1.00 65.56  ? 340 SER D CB  1 
ATOM 11068 O OG  . SER D 1 340 ? -8.916  -61.652 39.359  1.00 65.03  ? 340 SER D OG  1 
ATOM 11069 N N   . ILE D 1 341 ? -5.328  -63.867 40.729  1.00 59.76  ? 341 ILE D N   1 
ATOM 11070 C CA  . ILE D 1 341 ? -4.074  -64.613 40.675  1.00 57.00  ? 341 ILE D CA  1 
ATOM 11071 C C   . ILE D 1 341 ? -4.169  -65.888 41.506  1.00 63.30  ? 341 ILE D C   1 
ATOM 11072 O O   . ILE D 1 341 ? -3.665  -66.945 41.104  1.00 70.63  ? 341 ILE D O   1 
ATOM 11073 C CB  . ILE D 1 341 ? -2.908  -63.718 41.130  1.00 47.39  ? 341 ILE D CB  1 
ATOM 11074 C CG1 . ILE D 1 341 ? -2.668  -62.610 40.101  1.00 54.67  ? 341 ILE D CG1 1 
ATOM 11075 C CG2 . ILE D 1 341 ? -1.646  -64.541 41.346  1.00 55.27  ? 341 ILE D CG2 1 
ATOM 11076 C CD1 . ILE D 1 341 ? -1.492  -61.719 40.425  1.00 63.20  ? 341 ILE D CD1 1 
ATOM 11077 N N   . ALA D 1 342 ? -4.821  -65.815 42.668  1.00 61.36  ? 342 ALA D N   1 
ATOM 11078 C CA  . ALA D 1 342 ? -5.004  -67.013 43.481  1.00 62.50  ? 342 ALA D CA  1 
ATOM 11079 C C   . ALA D 1 342 ? -5.800  -68.073 42.728  1.00 66.66  ? 342 ALA D C   1 
ATOM 11080 O O   . ALA D 1 342 ? -5.431  -69.252 42.727  1.00 66.36  ? 342 ALA D O   1 
ATOM 11081 C CB  . ALA D 1 342 ? -5.688  -66.656 44.801  1.00 61.26  ? 342 ALA D CB  1 
ATOM 11082 N N   . GLU D 1 343 ? -6.895  -67.669 42.077  1.00 64.54  ? 343 GLU D N   1 
ATOM 11083 C CA  . GLU D 1 343 ? -7.685  -68.626 41.306  1.00 70.30  ? 343 GLU D CA  1 
ATOM 11084 C C   . GLU D 1 343 ? -6.894  -69.177 40.128  1.00 75.33  ? 343 GLU D C   1 
ATOM 11085 O O   . GLU D 1 343 ? -7.004  -70.364 39.799  1.00 68.01  ? 343 GLU D O   1 
ATOM 11086 C CB  . GLU D 1 343 ? -8.978  -67.975 40.815  1.00 73.67  ? 343 GLU D CB  1 
ATOM 11087 C CG  . GLU D 1 343 ? -10.042 -67.805 41.877  1.00 72.45  ? 343 GLU D CG  1 
ATOM 11088 C CD  . GLU D 1 343 ? -11.367 -67.374 41.286  1.00 80.10  ? 343 GLU D CD  1 
ATOM 11089 O OE1 . GLU D 1 343 ? -11.361 -66.816 40.169  1.00 76.12  ? 343 GLU D OE1 1 
ATOM 11090 O OE2 . GLU D 1 343 ? -12.413 -67.601 41.928  1.00 91.66  ? 343 GLU D OE2 1 
ATOM 11091 N N   . SER D 1 344 ? -6.097  -68.329 39.474  1.00 79.06  ? 344 SER D N   1 
ATOM 11092 C CA  . SER D 1 344 ? -5.281  -68.801 38.360  1.00 73.85  ? 344 SER D CA  1 
ATOM 11093 C C   . SER D 1 344 ? -4.241  -69.810 38.821  1.00 69.39  ? 344 SER D C   1 
ATOM 11094 O O   . SER D 1 344 ? -3.893  -70.729 38.070  1.00 66.28  ? 344 SER D O   1 
ATOM 11095 C CB  . SER D 1 344 ? -4.602  -67.624 37.665  1.00 75.81  ? 344 SER D CB  1 
ATOM 11096 O OG  . SER D 1 344 ? -3.979  -68.037 36.461  1.00 79.95  ? 344 SER D OG  1 
ATOM 11097 N N   . MET D 1 345 ? -3.732  -69.662 40.041  1.00 71.37  ? 345 MET D N   1 
ATOM 11098 C CA  . MET D 1 345 ? -2.717  -70.587 40.527  1.00 78.19  ? 345 MET D CA  1 
ATOM 11099 C C   . MET D 1 345 ? -3.304  -71.853 41.138  1.00 80.75  ? 345 MET D C   1 
ATOM 11100 O O   . MET D 1 345 ? -2.633  -72.892 41.143  1.00 75.10  ? 345 MET D O   1 
ATOM 11101 C CB  . MET D 1 345 ? -1.808  -69.890 41.544  1.00 76.50  ? 345 MET D CB  1 
ATOM 11102 C CG  . MET D 1 345 ? -1.003  -68.755 40.941  1.00 72.01  ? 345 MET D CG  1 
ATOM 11103 S SD  . MET D 1 345 ? 0.393   -68.292 41.971  1.00 90.11  ? 345 MET D SD  1 
ATOM 11104 C CE  . MET D 1 345 ? 1.323   -69.823 41.965  1.00 92.67  ? 345 MET D CE  1 
ATOM 11105 N N   . LYS D 1 346 ? -4.538  -71.803 41.648  1.00 82.08  ? 346 LYS D N   1 
ATOM 11106 C CA  . LYS D 1 346 ? -5.150  -73.020 42.166  1.00 76.78  ? 346 LYS D CA  1 
ATOM 11107 C C   . LYS D 1 346 ? -5.497  -74.003 41.055  1.00 82.16  ? 346 LYS D C   1 
ATOM 11108 O O   . LYS D 1 346 ? -5.605  -75.205 41.318  1.00 81.58  ? 346 LYS D O   1 
ATOM 11109 C CB  . LYS D 1 346 ? -6.407  -72.693 42.978  1.00 76.08  ? 346 LYS D CB  1 
ATOM 11110 C CG  . LYS D 1 346 ? -6.915  -73.861 43.823  1.00 88.41  ? 346 LYS D CG  1 
ATOM 11111 C CD  . LYS D 1 346 ? -8.364  -73.674 44.237  1.00 94.56  ? 346 LYS D CD  1 
ATOM 11112 C CE  . LYS D 1 346 ? -8.863  -74.863 45.045  1.00 100.08 ? 346 LYS D CE  1 
ATOM 11113 N NZ  . LYS D 1 346 ? -8.731  -76.141 44.289  1.00 103.69 ? 346 LYS D NZ  1 
ATOM 11114 N N   . PHE D 1 347 ? -5.658  -73.525 39.821  1.00 81.36  ? 347 PHE D N   1 
ATOM 11115 C CA  . PHE D 1 347 ? -5.994  -74.378 38.692  1.00 77.59  ? 347 PHE D CA  1 
ATOM 11116 C C   . PHE D 1 347 ? -4.840  -74.527 37.703  1.00 68.30  ? 347 PHE D C   1 
ATOM 11117 O O   . PHE D 1 347 ? -5.036  -75.088 36.619  1.00 67.02  ? 347 PHE D O   1 
ATOM 11118 C CB  . PHE D 1 347 ? -7.240  -73.844 37.981  1.00 72.11  ? 347 PHE D CB  1 
ATOM 11119 C CG  . PHE D 1 347 ? -8.461  -73.800 38.855  1.00 73.31  ? 347 PHE D CG  1 
ATOM 11120 C CD1 . PHE D 1 347 ? -9.068  -74.971 39.282  1.00 75.12  ? 347 PHE D CD1 1 
ATOM 11121 C CD2 . PHE D 1 347 ? -9.007  -72.590 39.246  1.00 81.06  ? 347 PHE D CD2 1 
ATOM 11122 C CE1 . PHE D 1 347 ? -10.193 -74.933 40.086  1.00 80.04  ? 347 PHE D CE1 1 
ATOM 11123 C CE2 . PHE D 1 347 ? -10.133 -72.546 40.052  1.00 83.59  ? 347 PHE D CE2 1 
ATOM 11124 C CZ  . PHE D 1 347 ? -10.724 -73.720 40.471  1.00 80.41  ? 347 PHE D CZ  1 
ATOM 11125 N N   . GLY D 1 348 ? -3.651  -74.040 38.047  1.00 71.11  ? 348 GLY D N   1 
ATOM 11126 C CA  . GLY D 1 348 ? -2.482  -74.239 37.207  1.00 71.94  ? 348 GLY D CA  1 
ATOM 11127 C C   . GLY D 1 348 ? -2.499  -73.506 35.885  1.00 69.81  ? 348 GLY D C   1 
ATOM 11128 O O   . GLY D 1 348 ? -1.867  -73.963 34.927  1.00 70.96  ? 348 GLY D O   1 
ATOM 11129 N N   . VAL D 1 349 ? -3.199  -72.383 35.802  1.00 72.32  ? 349 VAL D N   1 
ATOM 11130 C CA  . VAL D 1 349 ? -3.280  -71.583 34.585  1.00 72.16  ? 349 VAL D CA  1 
ATOM 11131 C C   . VAL D 1 349 ? -2.256  -70.459 34.690  1.00 69.03  ? 349 VAL D C   1 
ATOM 11132 O O   . VAL D 1 349 ? -2.382  -69.606 35.581  1.00 64.54  ? 349 VAL D O   1 
ATOM 11133 C CB  . VAL D 1 349 ? -4.695  -71.021 34.378  1.00 71.76  ? 349 VAL D CB  1 
ATOM 11134 C CG1 . VAL D 1 349 ? -4.754  -70.169 33.119  1.00 71.60  ? 349 VAL D CG1 1 
ATOM 11135 C CG2 . VAL D 1 349 ? -5.714  -72.151 34.318  1.00 72.82  ? 349 VAL D CG2 1 
ATOM 11136 N N   . PRO D 1 350 ? -1.242  -70.414 33.822  1.00 71.17  ? 350 PRO D N   1 
ATOM 11137 C CA  . PRO D 1 350 ? -0.261  -69.323 33.889  1.00 71.65  ? 350 PRO D CA  1 
ATOM 11138 C C   . PRO D 1 350 ? -0.900  -67.973 33.594  1.00 67.35  ? 350 PRO D C   1 
ATOM 11139 O O   . PRO D 1 350 ? -1.974  -67.878 33.000  1.00 75.83  ? 350 PRO D O   1 
ATOM 11140 C CB  . PRO D 1 350 ? 0.770   -69.703 32.821  1.00 72.00  ? 350 PRO D CB  1 
ATOM 11141 C CG  . PRO D 1 350 ? 0.045   -70.623 31.900  1.00 77.52  ? 350 PRO D CG  1 
ATOM 11142 C CD  . PRO D 1 350 ? -0.919  -71.383 32.763  1.00 76.23  ? 350 PRO D CD  1 
ATOM 11143 N N   . VAL D 1 351 ? -0.212  -66.916 34.017  1.00 68.54  ? 351 VAL D N   1 
ATOM 11144 C CA  . VAL D 1 351 ? -0.783  -65.573 34.083  1.00 66.17  ? 351 VAL D CA  1 
ATOM 11145 C C   . VAL D 1 351 ? -0.122  -64.678 33.043  1.00 72.96  ? 351 VAL D C   1 
ATOM 11146 O O   . VAL D 1 351 ? 1.108   -64.673 32.900  1.00 75.01  ? 351 VAL D O   1 
ATOM 11147 C CB  . VAL D 1 351 ? -0.635  -64.971 35.488  1.00 58.20  ? 351 VAL D CB  1 
ATOM 11148 C CG1 . VAL D 1 351 ? -1.326  -63.618 35.563  1.00 60.44  ? 351 VAL D CG1 1 
ATOM 11149 C CG2 . VAL D 1 351 ? -1.194  -65.922 36.535  1.00 62.76  ? 351 VAL D CG2 1 
ATOM 11150 N N   . ILE D 1 352 ? -0.945  -63.925 32.318  1.00 68.88  ? 352 ILE D N   1 
ATOM 11151 C CA  . ILE D 1 352 ? -0.502  -62.845 31.449  1.00 69.61  ? 352 ILE D CA  1 
ATOM 11152 C C   . ILE D 1 352 ? -0.834  -61.556 32.192  1.00 65.37  ? 352 ILE D C   1 
ATOM 11153 O O   . ILE D 1 352 ? -2.001  -61.150 32.272  1.00 67.57  ? 352 ILE D O   1 
ATOM 11154 C CB  . ILE D 1 352 ? -1.183  -62.902 30.078  1.00 71.88  ? 352 ILE D CB  1 
ATOM 11155 C CG1 . ILE D 1 352 ? -1.213  -64.337 29.549  1.00 71.24  ? 352 ILE D CG1 1 
ATOM 11156 C CG2 . ILE D 1 352 ? -0.483  -61.980 29.093  1.00 69.31  ? 352 ILE D CG2 1 
ATOM 11157 C CD1 . ILE D 1 352 ? 0.150   -64.911 29.282  1.00 85.10  ? 352 ILE D CD1 1 
ATOM 11158 N N   . ALA D 1 353 ? 0.189   -60.914 32.746  1.00 72.71  ? 353 ALA D N   1 
ATOM 11159 C CA  . ALA D 1 353 ? -0.009  -59.760 33.608  1.00 69.29  ? 353 ALA D CA  1 
ATOM 11160 C C   . ALA D 1 353 ? -0.250  -58.506 32.781  1.00 73.02  ? 353 ALA D C   1 
ATOM 11161 O O   . ALA D 1 353 ? 0.554   -58.156 31.909  1.00 73.91  ? 353 ALA D O   1 
ATOM 11162 C CB  . ALA D 1 353 ? 1.198   -59.566 34.524  1.00 53.64  ? 353 ALA D CB  1 
ATOM 11163 N N   . MET D 1 354 ? -1.369  -57.823 33.059  1.00 65.65  ? 354 MET D N   1 
ATOM 11164 C CA  . MET D 1 354 ? -1.715  -56.556 32.430  1.00 77.22  ? 354 MET D CA  1 
ATOM 11165 C C   . MET D 1 354 ? -2.318  -55.653 33.512  1.00 69.94  ? 354 MET D C   1 
ATOM 11166 O O   . MET D 1 354 ? -3.500  -55.315 33.499  1.00 71.60  ? 354 MET D O   1 
ATOM 11167 C CB  . MET D 1 354 ? -2.671  -56.750 31.251  1.00 77.67  ? 354 MET D CB  1 
ATOM 11168 C CG  . MET D 1 354 ? -2.025  -57.397 30.032  1.00 82.65  ? 354 MET D CG  1 
ATOM 11169 S SD  . MET D 1 354 ? -3.092  -57.451 28.577  1.00 75.43  ? 354 MET D SD  1 
ATOM 11170 C CE  . MET D 1 354 ? -3.609  -55.738 28.471  1.00 77.68  ? 354 MET D CE  1 
ATOM 11171 N N   . ALA D 1 355 ? -1.487  -55.261 34.473  1.00 69.84  ? 355 ALA D N   1 
ATOM 11172 C CA  . ALA D 1 355 ? -1.920  -54.422 35.576  1.00 73.70  ? 355 ALA D CA  1 
ATOM 11173 C C   . ALA D 1 355 ? -1.917  -52.951 35.167  1.00 84.84  ? 355 ALA D C   1 
ATOM 11174 O O   . ALA D 1 355 ? -1.435  -52.576 34.095  1.00 88.81  ? 355 ALA D O   1 
ATOM 11175 C CB  . ALA D 1 355 ? -1.022  -54.637 36.791  1.00 71.22  ? 355 ALA D CB  1 
ATOM 11176 N N   . ARG D 1 356 ? -2.468  -52.106 36.040  1.00 83.58  ? 356 ARG D N   1 
ATOM 11177 C CA  . ARG D 1 356 ? -2.481  -50.672 35.765  1.00 98.28  ? 356 ARG D CA  1 
ATOM 11178 C C   . ARG D 1 356 ? -2.436  -49.836 37.040  1.00 105.90 ? 356 ARG D C   1 
ATOM 11179 O O   . ARG D 1 356 ? -1.598  -48.936 37.160  1.00 114.72 ? 356 ARG D O   1 
ATOM 11180 C CB  . ARG D 1 356 ? -3.710  -50.296 34.934  1.00 110.87 ? 356 ARG D CB  1 
ATOM 11181 C CG  . ARG D 1 356 ? -3.384  -49.372 33.765  1.00 117.71 ? 356 ARG D CG  1 
ATOM 11182 C CD  . ARG D 1 356 ? -4.633  -48.893 33.039  1.00 126.48 ? 356 ARG D CD  1 
ATOM 11183 N NE  . ARG D 1 356 ? -5.301  -47.810 33.755  1.00 135.32 ? 356 ARG D NE  1 
ATOM 11184 C CZ  . ARG D 1 356 ? -4.964  -46.530 33.658  1.00 138.79 ? 356 ARG D CZ  1 
ATOM 11185 N NH1 . ARG D 1 356 ? -3.958  -46.136 32.894  1.00 142.88 ? 356 ARG D NH1 1 
ATOM 11186 N NH2 . ARG D 1 356 ? -5.652  -45.624 34.345  1.00 134.55 ? 356 ARG D NH2 1 
ATOM 11187 N N   . HIS D 1 357 ? -3.325  -50.109 37.991  1.00 99.14  ? 357 HIS D N   1 
ATOM 11188 C CA  . HIS D 1 357 ? -3.456  -49.283 39.182  1.00 103.91 ? 357 HIS D CA  1 
ATOM 11189 C C   . HIS D 1 357 ? -3.501  -50.156 40.430  1.00 101.65 ? 357 HIS D C   1 
ATOM 11190 O O   . HIS D 1 357 ? -3.554  -51.386 40.357  1.00 97.13  ? 357 HIS D O   1 
ATOM 11191 C CB  . HIS D 1 357 ? -4.703  -48.389 39.106  1.00 107.57 ? 357 HIS D CB  1 
ATOM 11192 C CG  . HIS D 1 357 ? -5.968  -49.140 38.840  1.00 115.16 ? 357 HIS D CG  1 
ATOM 11193 N ND1 . HIS D 1 357 ? -6.800  -49.582 39.848  1.00 113.81 ? 357 HIS D ND1 1 
ATOM 11194 C CD2 . HIS D 1 357 ? -6.551  -49.526 37.678  1.00 116.16 ? 357 HIS D CD2 1 
ATOM 11195 C CE1 . HIS D 1 357 ? -7.836  -50.208 39.321  1.00 109.55 ? 357 HIS D CE1 1 
ATOM 11196 N NE2 . HIS D 1 357 ? -7.709  -50.187 38.006  1.00 116.38 ? 357 HIS D NE2 1 
ATOM 11197 N N   . LEU D 1 358 ? -3.472  -49.492 41.583  1.00 103.16 ? 358 LEU D N   1 
ATOM 11198 C CA  . LEU D 1 358 ? -3.504  -50.134 42.904  1.00 102.01 ? 358 LEU D CA  1 
ATOM 11199 C C   . LEU D 1 358 ? -2.277  -51.041 43.036  1.00 94.61  ? 358 LEU D C   1 
ATOM 11200 O O   . LEU D 1 358 ? -1.232  -50.787 42.426  1.00 90.50  ? 358 LEU D O   1 
ATOM 11201 C CB  . LEU D 1 358 ? -4.837  -50.834 43.111  1.00 94.70  ? 358 LEU D CB  1 
ATOM 11202 C CG  . LEU D 1 358 ? -6.070  -49.930 43.141  1.00 99.02  ? 358 LEU D CG  1 
ATOM 11203 C CD1 . LEU D 1 358 ? -7.321  -50.721 43.499  1.00 98.28  ? 358 LEU D CD1 1 
ATOM 11204 C CD2 . LEU D 1 358 ? -5.858  -48.781 44.109  1.00 95.00  ? 358 LEU D CD2 1 
ATOM 11205 N N   . ASP D 1 359 ? -2.390  -52.098 43.836  1.00 88.30  ? 359 ASP D N   1 
ATOM 11206 C CA  . ASP D 1 359 ? -1.306  -53.043 44.065  1.00 84.53  ? 359 ASP D CA  1 
ATOM 11207 C C   . ASP D 1 359 ? -1.199  -54.097 42.973  1.00 75.10  ? 359 ASP D C   1 
ATOM 11208 O O   . ASP D 1 359 ? -0.427  -55.050 43.126  1.00 65.10  ? 359 ASP D O   1 
ATOM 11209 C CB  . ASP D 1 359 ? -1.492  -53.729 45.419  1.00 74.56  ? 359 ASP D CB  1 
ATOM 11210 C CG  . ASP D 1 359 ? -2.750  -54.578 45.470  1.00 78.76  ? 359 ASP D CG  1 
ATOM 11211 O OD1 . ASP D 1 359 ? -3.719  -54.254 44.744  1.00 87.69  ? 359 ASP D OD1 1 
ATOM 11212 O OD2 . ASP D 1 359 ? -2.765  -55.576 46.225  1.00 76.00  ? 359 ASP D OD2 1 
ATOM 11213 N N   . GLN D 1 360 ? -1.954  -53.942 41.890  1.00 76.59  ? 360 GLN D N   1 
ATOM 11214 C CA  . GLN D 1 360 ? -1.935  -54.937 40.821  1.00 66.26  ? 360 GLN D CA  1 
ATOM 11215 C C   . GLN D 1 360 ? -0.567  -55.096 40.163  1.00 63.88  ? 360 GLN D C   1 
ATOM 11216 O O   . GLN D 1 360 ? -0.197  -56.246 39.864  1.00 65.23  ? 360 GLN D O   1 
ATOM 11217 C CB  . GLN D 1 360 ? -3.008  -54.590 39.781  1.00 71.52  ? 360 GLN D CB  1 
ATOM 11218 C CG  . GLN D 1 360 ? -4.415  -54.492 40.353  1.00 79.11  ? 360 GLN D CG  1 
ATOM 11219 C CD  . GLN D 1 360 ? -5.390  -53.842 39.394  1.00 89.45  ? 360 GLN D CD  1 
ATOM 11220 O OE1 . GLN D 1 360 ? -5.113  -53.714 38.200  1.00 91.98  ? 360 GLN D OE1 1 
ATOM 11221 N NE2 . GLN D 1 360 ? -6.537  -53.424 39.911  1.00 98.92  ? 360 GLN D NE2 1 
ATOM 11222 N N   . PRO D 1 361 ? 0.206   -54.038 39.886  1.00 61.94  ? 361 PRO D N   1 
ATOM 11223 C CA  . PRO D 1 361 ? 1.569   -54.278 39.373  1.00 65.56  ? 361 PRO D CA  1 
ATOM 11224 C C   . PRO D 1 361 ? 2.415   -55.118 40.317  1.00 66.78  ? 361 PRO D C   1 
ATOM 11225 O O   . PRO D 1 361 ? 3.011   -56.114 39.884  1.00 69.97  ? 361 PRO D O   1 
ATOM 11226 C CB  . PRO D 1 361 ? 2.123   -52.859 39.194  1.00 65.39  ? 361 PRO D CB  1 
ATOM 11227 C CG  . PRO D 1 361 ? 0.926   -52.023 38.958  1.00 63.07  ? 361 PRO D CG  1 
ATOM 11228 C CD  . PRO D 1 361 ? -0.135  -52.603 39.849  1.00 65.87  ? 361 PRO D CD  1 
ATOM 11229 N N   . LEU D 1 362 ? 2.463   -54.755 41.605  1.00 66.24  ? 362 LEU D N   1 
ATOM 11230 C CA  . LEU D 1 362 ? 3.238   -55.534 42.568  1.00 69.20  ? 362 LEU D CA  1 
ATOM 11231 C C   . LEU D 1 362 ? 2.818   -56.998 42.561  1.00 66.60  ? 362 LEU D C   1 
ATOM 11232 O O   . LEU D 1 362 ? 3.665   -57.892 42.658  1.00 64.71  ? 362 LEU D O   1 
ATOM 11233 C CB  . LEU D 1 362 ? 3.093   -54.949 43.975  1.00 62.21  ? 362 LEU D CB  1 
ATOM 11234 C CG  . LEU D 1 362 ? 3.640   -53.548 44.260  1.00 54.74  ? 362 LEU D CG  1 
ATOM 11235 C CD1 . LEU D 1 362 ? 4.991   -53.334 43.592  1.00 62.07  ? 362 LEU D CD1 1 
ATOM 11236 C CD2 . LEU D 1 362 ? 2.641   -52.465 43.856  1.00 67.38  ? 362 LEU D CD2 1 
ATOM 11237 N N   . ASN D 1 363 ? 1.514   -57.262 42.452  1.00 58.31  ? 363 ASN D N   1 
ATOM 11238 C CA  . ASN D 1 363 ? 1.056   -58.645 42.347  1.00 52.79  ? 363 ASN D CA  1 
ATOM 11239 C C   . ASN D 1 363 ? 1.633   -59.309 41.105  1.00 61.64  ? 363 ASN D C   1 
ATOM 11240 O O   . ASN D 1 363 ? 2.200   -60.405 41.177  1.00 62.34  ? 363 ASN D O   1 
ATOM 11241 C CB  . ASN D 1 363 ? -0.474  -58.699 42.324  1.00 57.84  ? 363 ASN D CB  1 
ATOM 11242 C CG  . ASN D 1 363 ? -1.103  -58.127 43.581  1.00 63.75  ? 363 ASN D CG  1 
ATOM 11243 O OD1 . ASN D 1 363 ? -0.450  -58.000 44.620  1.00 72.19  ? 363 ASN D OD1 1 
ATOM 11244 N ND2 . ASN D 1 363 ? -2.384  -57.788 43.497  1.00 58.31  ? 363 ASN D ND2 1 
ATOM 11245 N N   . GLY D 1 364 ? 1.521   -58.638 39.956  1.00 65.65  ? 364 GLY D N   1 
ATOM 11246 C CA  . GLY D 1 364 ? 1.960   -59.191 38.688  1.00 56.04  ? 364 GLY D CA  1 
ATOM 11247 C C   . GLY D 1 364 ? 3.389   -59.685 38.716  1.00 64.49  ? 364 GLY D C   1 
ATOM 11248 O O   . GLY D 1 364 ? 3.632   -60.889 38.591  1.00 71.05  ? 364 GLY D O   1 
ATOM 11249 N N   . LYS D 1 365 ? 4.341   -58.762 38.904  1.00 64.13  ? 365 LYS D N   1 
ATOM 11250 C CA  . LYS D 1 365 ? 5.741   -59.154 39.036  1.00 74.40  ? 365 LYS D CA  1 
ATOM 11251 C C   . LYS D 1 365 ? 5.928   -60.222 40.106  1.00 66.17  ? 365 LYS D C   1 
ATOM 11252 O O   . LYS D 1 365 ? 6.792   -61.095 39.954  1.00 73.21  ? 365 LYS D O   1 
ATOM 11253 C CB  . LYS D 1 365 ? 6.614   -57.935 39.343  1.00 65.16  ? 365 LYS D CB  1 
ATOM 11254 C CG  . LYS D 1 365 ? 6.255   -57.195 40.626  1.00 70.83  ? 365 LYS D CG  1 
ATOM 11255 C CD  . LYS D 1 365 ? 6.964   -55.845 40.691  1.00 67.22  ? 365 LYS D CD  1 
ATOM 11256 C CE  . LYS D 1 365 ? 8.472   -55.997 40.536  1.00 66.23  ? 365 LYS D CE  1 
ATOM 11257 N NZ  . LYS D 1 365 ? 9.171   -54.680 40.561  1.00 60.85  ? 365 LYS D NZ  1 
ATOM 11258 N N   . LEU D 1 366 ? 5.133   -60.180 41.179  1.00 62.93  ? 366 LEU D N   1 
ATOM 11259 C CA  . LEU D 1 366 ? 5.177   -61.249 42.172  1.00 65.11  ? 366 LEU D CA  1 
ATOM 11260 C C   . LEU D 1 366 ? 5.002   -62.610 41.504  1.00 67.11  ? 366 LEU D C   1 
ATOM 11261 O O   . LEU D 1 366 ? 5.879   -63.477 41.591  1.00 64.41  ? 366 LEU D O   1 
ATOM 11262 C CB  . LEU D 1 366 ? 4.105   -61.024 43.237  1.00 63.52  ? 366 LEU D CB  1 
ATOM 11263 C CG  . LEU D 1 366 ? 4.064   -62.056 44.367  1.00 66.42  ? 366 LEU D CG  1 
ATOM 11264 C CD1 . LEU D 1 366 ? 5.321   -62.005 45.224  1.00 63.88  ? 366 LEU D CD1 1 
ATOM 11265 C CD2 . LEU D 1 366 ? 2.822   -61.847 45.220  1.00 64.58  ? 366 LEU D CD2 1 
ATOM 11266 N N   . ALA D 1 367 ? 3.886   -62.801 40.796  1.00 69.69  ? 367 ALA D N   1 
ATOM 11267 C CA  . ALA D 1 367 ? 3.695   -64.042 40.051  1.00 75.23  ? 367 ALA D CA  1 
ATOM 11268 C C   . ALA D 1 367 ? 4.737   -64.225 38.957  1.00 72.53  ? 367 ALA D C   1 
ATOM 11269 O O   . ALA D 1 367 ? 5.019   -65.364 38.568  1.00 74.35  ? 367 ALA D O   1 
ATOM 11270 C CB  . ALA D 1 367 ? 2.283   -64.097 39.469  1.00 71.79  ? 367 ALA D CB  1 
ATOM 11271 N N   . ALA D 1 368 ? 5.338   -63.137 38.471  1.00 69.56  ? 368 ALA D N   1 
ATOM 11272 C CA  . ALA D 1 368 ? 6.453   -63.242 37.537  1.00 69.54  ? 368 ALA D CA  1 
ATOM 11273 C C   . ALA D 1 368 ? 7.764   -63.566 38.233  1.00 72.05  ? 368 ALA D C   1 
ATOM 11274 O O   . ALA D 1 368 ? 8.656   -64.151 37.610  1.00 74.13  ? 368 ALA D O   1 
ATOM 11275 C CB  . ALA D 1 368 ? 6.604   -61.950 36.737  1.00 64.95  ? 368 ALA D CB  1 
ATOM 11276 N N   . GLU D 1 369 ? 7.891   -63.214 39.512  1.00 76.94  ? 369 GLU D N   1 
ATOM 11277 C CA  . GLU D 1 369 ? 9.100   -63.542 40.260  1.00 72.01  ? 369 GLU D CA  1 
ATOM 11278 C C   . GLU D 1 369 ? 9.208   -65.043 40.502  1.00 73.70  ? 369 GLU D C   1 
ATOM 11279 O O   . GLU D 1 369 ? 10.302  -65.614 40.407  1.00 73.45  ? 369 GLU D O   1 
ATOM 11280 C CB  . GLU D 1 369 ? 9.115   -62.775 41.582  1.00 75.08  ? 369 GLU D CB  1 
ATOM 11281 C CG  . GLU D 1 369 ? 10.109  -63.277 42.614  1.00 75.34  ? 369 GLU D CG  1 
ATOM 11282 C CD  . GLU D 1 369 ? 10.045  -62.481 43.907  1.00 82.63  ? 369 GLU D CD  1 
ATOM 11283 O OE1 . GLU D 1 369 ? 10.012  -61.233 43.836  1.00 85.43  ? 369 GLU D OE1 1 
ATOM 11284 O OE2 . GLU D 1 369 ? 10.013  -63.100 44.993  1.00 82.38  ? 369 GLU D OE2 1 
ATOM 11285 N N   . VAL D 1 370 ? 8.086   -65.700 40.807  1.00 70.54  ? 370 VAL D N   1 
ATOM 11286 C CA  . VAL D 1 370 ? 8.099   -67.138 41.074  1.00 74.39  ? 370 VAL D CA  1 
ATOM 11287 C C   . VAL D 1 370 ? 8.066   -67.977 39.806  1.00 80.57  ? 370 VAL D C   1 
ATOM 11288 O O   . VAL D 1 370 ? 8.360   -69.177 39.864  1.00 80.04  ? 370 VAL D O   1 
ATOM 11289 C CB  . VAL D 1 370 ? 6.921   -67.539 41.980  1.00 71.34  ? 370 VAL D CB  1 
ATOM 11290 C CG1 . VAL D 1 370 ? 6.977   -66.768 43.293  1.00 68.74  ? 370 VAL D CG1 1 
ATOM 11291 C CG2 . VAL D 1 370 ? 5.598   -67.294 41.273  1.00 70.92  ? 370 VAL D CG2 1 
ATOM 11292 N N   . GLY D 1 371 ? 7.713   -67.383 38.668  1.00 81.26  ? 371 GLY D N   1 
ATOM 11293 C CA  . GLY D 1 371 ? 7.801   -68.059 37.390  1.00 85.06  ? 371 GLY D CA  1 
ATOM 11294 C C   . GLY D 1 371 ? 6.515   -68.639 36.843  1.00 92.16  ? 371 GLY D C   1 
ATOM 11295 O O   . GLY D 1 371 ? 6.576   -69.438 35.901  1.00 96.66  ? 371 GLY D O   1 
ATOM 11296 N N   . VAL D 1 372 ? 5.362   -68.271 37.387  1.00 82.64  ? 372 VAL D N   1 
ATOM 11297 C CA  . VAL D 1 372 ? 4.084   -68.800 36.923  1.00 81.60  ? 372 VAL D CA  1 
ATOM 11298 C C   . VAL D 1 372 ? 3.339   -67.786 36.051  1.00 79.43  ? 372 VAL D C   1 
ATOM 11299 O O   . VAL D 1 372 ? 2.139   -67.932 35.823  1.00 77.87  ? 372 VAL D O   1 
ATOM 11300 C CB  . VAL D 1 372 ? 3.209   -69.272 38.095  1.00 85.05  ? 372 VAL D CB  1 
ATOM 11301 C CG1 . VAL D 1 372 ? 3.912   -70.373 38.873  1.00 82.30  ? 372 VAL D CG1 1 
ATOM 11302 C CG2 . VAL D 1 372 ? 2.853   -68.103 39.001  1.00 82.09  ? 372 VAL D CG2 1 
ATOM 11303 N N   . GLY D 1 373 ? 4.030   -66.764 35.560  1.00 74.71  ? 373 GLY D N   1 
ATOM 11304 C CA  . GLY D 1 373 ? 3.386   -65.781 34.712  1.00 74.62  ? 373 GLY D CA  1 
ATOM 11305 C C   . GLY D 1 373 ? 4.415   -64.876 34.070  1.00 73.36  ? 373 GLY D C   1 
ATOM 11306 O O   . GLY D 1 373 ? 5.617   -64.979 34.325  1.00 66.41  ? 373 GLY D O   1 
ATOM 11307 N N   . MET D 1 374 ? 3.917   -63.979 33.221  1.00 75.69  ? 374 MET D N   1 
ATOM 11308 C CA  . MET D 1 374 ? 4.769   -63.013 32.540  1.00 67.21  ? 374 MET D CA  1 
ATOM 11309 C C   . MET D 1 374 ? 3.988   -61.733 32.287  1.00 66.92  ? 374 MET D C   1 
ATOM 11310 O O   . MET D 1 374 ? 2.810   -61.778 31.924  1.00 75.09  ? 374 MET D O   1 
ATOM 11311 C CB  . MET D 1 374 ? 5.300   -63.560 31.213  1.00 77.93  ? 374 MET D CB  1 
ATOM 11312 C CG  . MET D 1 374 ? 6.415   -62.716 30.617  1.00 90.13  ? 374 MET D CG  1 
ATOM 11313 S SD  . MET D 1 374 ? 6.381   -62.639 28.816  1.00 117.71 ? 374 MET D SD  1 
ATOM 11314 C CE  . MET D 1 374 ? 6.455   -64.378 28.399  1.00 99.60  ? 374 MET D CE  1 
ATOM 11315 N N   . GLU D 1 375 ? 4.650   -60.597 32.478  1.00 68.05  ? 375 GLU D N   1 
ATOM 11316 C CA  . GLU D 1 375 ? 4.035   -59.296 32.268  1.00 82.33  ? 375 GLU D CA  1 
ATOM 11317 C C   . GLU D 1 375 ? 4.260   -58.821 30.839  1.00 88.29  ? 375 GLU D C   1 
ATOM 11318 O O   . GLU D 1 375 ? 5.276   -59.136 30.210  1.00 88.11  ? 375 GLU D O   1 
ATOM 11319 C CB  . GLU D 1 375 ? 4.603   -58.261 33.241  1.00 79.90  ? 375 GLU D CB  1 
ATOM 11320 C CG  . GLU D 1 375 ? 5.064   -58.830 34.565  1.00 73.02  ? 375 GLU D CG  1 
ATOM 11321 C CD  . GLU D 1 375 ? 5.569   -57.757 35.508  1.00 74.68  ? 375 GLU D CD  1 
ATOM 11322 O OE1 . GLU D 1 375 ? 4.842   -56.762 35.720  1.00 76.21  ? 375 GLU D OE1 1 
ATOM 11323 O OE2 . GLU D 1 375 ? 6.695   -57.902 36.026  1.00 69.60  ? 375 GLU D OE2 1 
ATOM 11324 N N   . VAL D 1 376 ? 3.297   -58.053 30.326  1.00 93.26  ? 376 VAL D N   1 
ATOM 11325 C CA  . VAL D 1 376 ? 3.473   -57.431 29.023  1.00 103.15 ? 376 VAL D CA  1 
ATOM 11326 C C   . VAL D 1 376 ? 4.441   -56.261 29.157  1.00 108.28 ? 376 VAL D C   1 
ATOM 11327 O O   . VAL D 1 376 ? 4.487   -55.574 30.189  1.00 104.99 ? 376 VAL D O   1 
ATOM 11328 C CB  . VAL D 1 376 ? 2.125   -56.982 28.433  1.00 100.76 ? 376 VAL D CB  1 
ATOM 11329 C CG1 . VAL D 1 376 ? 1.134   -58.131 28.448  1.00 85.12  ? 376 VAL D CG1 1 
ATOM 11330 C CG2 . VAL D 1 376 ? 1.568   -55.785 29.184  1.00 107.23 ? 376 VAL D CG2 1 
ATOM 11331 N N   . VAL D 1 377 ? 5.238   -56.040 28.117  1.00 109.44 ? 377 VAL D N   1 
ATOM 11332 C CA  . VAL D 1 377 ? 6.248   -54.989 28.124  1.00 111.57 ? 377 VAL D CA  1 
ATOM 11333 C C   . VAL D 1 377 ? 5.603   -53.698 27.642  1.00 118.71 ? 377 VAL D C   1 
ATOM 11334 O O   . VAL D 1 377 ? 5.126   -53.619 26.504  1.00 124.71 ? 377 VAL D O   1 
ATOM 11335 C CB  . VAL D 1 377 ? 7.453   -55.370 27.253  1.00 124.10 ? 377 VAL D CB  1 
ATOM 11336 C CG1 . VAL D 1 377 ? 8.597   -54.390 27.475  1.00 124.89 ? 377 VAL D CG1 1 
ATOM 11337 C CG2 . VAL D 1 377 ? 7.896   -56.794 27.549  1.00 121.62 ? 377 VAL D CG2 1 
ATOM 11338 N N   . ARG D 1 378 ? 5.553   -52.694 28.524  1.00 120.88 ? 378 ARG D N   1 
ATOM 11339 C CA  . ARG D 1 378 ? 4.899   -51.402 28.181  1.00 129.64 ? 378 ARG D CA  1 
ATOM 11340 C C   . ARG D 1 378 ? 5.766   -50.633 27.179  1.00 136.09 ? 378 ARG D C   1 
ATOM 11341 O O   . ARG D 1 378 ? 6.951   -50.400 27.485  1.00 135.02 ? 378 ARG D O   1 
ATOM 11342 C CB  . ARG D 1 378 ? 4.671   -50.572 29.448  1.00 130.13 ? 378 ARG D CB  1 
ATOM 11343 C CG  . ARG D 1 378 ? 3.669   -49.440 29.280  1.00 131.03 ? 378 ARG D CG  1 
ATOM 11344 C CD  . ARG D 1 378 ? 3.110   -48.961 30.607  1.00 132.49 ? 378 ARG D CD  1 
ATOM 11345 N NE  . ARG D 1 378 ? 1.655   -48.999 30.643  1.00 129.58 ? 378 ARG D NE  1 
ATOM 11346 C CZ  . ARG D 1 378 ? 0.940   -49.305 31.720  1.00 118.74 ? 378 ARG D CZ  1 
ATOM 11347 N NH1 . ARG D 1 378 ? 1.547   -49.603 32.855  1.00 108.18 ? 378 ARG D NH1 1 
ATOM 11348 N NH2 . ARG D 1 378 ? -0.379  -49.319 31.656  1.00 116.94 ? 378 ARG D NH2 1 
ATOM 11349 N N   . ASP D 1 379 ? 5.188   -50.253 26.036  1.00 139.36 ? 379 ASP D N   1 
ATOM 11350 C CA  . ASP D 1 379 ? 5.939   -49.461 25.024  1.00 143.00 ? 379 ASP D CA  1 
ATOM 11351 C C   . ASP D 1 379 ? 5.749   -47.969 25.322  1.00 143.00 ? 379 ASP D C   1 
ATOM 11352 O O   . ASP D 1 379 ? 6.661   -47.184 24.996  1.00 140.41 ? 379 ASP D O   1 
ATOM 11353 C CB  . ASP D 1 379 ? 5.502   -49.820 23.602  1.00 140.81 ? 379 ASP D CB  1 
ATOM 11354 C CG  . ASP D 1 379 ? 5.960   -51.200 23.165  1.00 141.76 ? 379 ASP D CG  1 
ATOM 11355 O OD1 . ASP D 1 379 ? 6.847   -51.761 23.839  1.00 142.72 ? 379 ASP D OD1 1 
ATOM 11356 O OD2 . ASP D 1 379 ? 5.424   -51.700 22.157  1.00 143.53 ? 379 ASP D OD2 1 
ATOM 11357 N N   . GLU D 1 380 ? 4.611   -47.602 25.920  1.00 142.95 ? 380 GLU D N   1 
ATOM 11358 C CA  . GLU D 1 380 ? 4.346   -46.182 26.270  1.00 143.29 ? 380 GLU D CA  1 
ATOM 11359 C C   . GLU D 1 380 ? 4.414   -46.020 27.791  1.00 147.19 ? 380 GLU D C   1 
ATOM 11360 O O   . GLU D 1 380 ? 5.363   -46.554 28.396  1.00 149.89 ? 380 GLU D O   1 
ATOM 11361 C CB  . GLU D 1 380 ? 2.982   -45.751 25.728  1.00 144.49 ? 380 GLU D CB  1 
ATOM 11362 C CG  . GLU D 1 380 ? 2.917   -45.705 24.211  1.00 150.94 ? 380 GLU D CG  1 
ATOM 11363 C CD  . GLU D 1 380 ? 1.547   -45.348 23.660  1.00 156.98 ? 380 GLU D CD  1 
ATOM 11364 O OE1 . GLU D 1 380 ? 0.585   -45.318 24.452  1.00 150.65 ? 380 GLU D OE1 1 
ATOM 11365 O OE2 . GLU D 1 380 ? 1.449   -45.091 22.444  1.00 159.20 ? 380 GLU D OE2 1 
ATOM 11366 N N   . ASN D 1 381 ? 3.448   -45.307 28.379  1.00 145.64 ? 381 ASN D N   1 
ATOM 11367 C CA  . ASN D 1 381 ? 3.398   -45.126 29.854  1.00 145.75 ? 381 ASN D CA  1 
ATOM 11368 C C   . ASN D 1 381 ? 1.948   -45.300 30.305  1.00 145.18 ? 381 ASN D C   1 
ATOM 11369 O O   . ASN D 1 381 ? 1.733   -45.728 31.456  1.00 147.30 ? 381 ASN D O   1 
ATOM 11370 C CB  . ASN D 1 381 ? 3.983   -43.779 30.293  1.00 131.72 ? 381 ASN D CB  1 
ATOM 11371 C CG  . ASN D 1 381 ? 3.661   -42.642 29.347  1.00 134.69 ? 381 ASN D CG  1 
ATOM 11372 O OD1 . ASN D 1 381 ? 2.538   -42.143 29.324  1.00 131.99 ? 381 ASN D OD1 1 
ATOM 11373 N ND2 . ASN D 1 381 ? 4.643   -42.214 28.570  1.00 136.76 ? 381 ASN D ND2 1 
ATOM 11374 N N   . GLY D 1 382 ? 0.995   -44.987 29.423  1.00 136.50 ? 382 GLY D N   1 
ATOM 11375 C CA  . GLY D 1 382 ? -0.433  -45.153 29.754  1.00 135.75 ? 382 GLY D CA  1 
ATOM 11376 C C   . GLY D 1 382 ? -0.897  -46.572 29.478  1.00 139.34 ? 382 GLY D C   1 
ATOM 11377 O O   . GLY D 1 382 ? -1.681  -47.102 30.290  1.00 143.32 ? 382 GLY D O   1 
ATOM 11378 N N   . LYS D 1 383 ? -0.437  -47.147 28.371  1.00 139.32 ? 383 LYS D N   1 
ATOM 11379 C CA  . LYS D 1 383 ? -0.982  -48.478 28.028  1.00 135.94 ? 383 LYS D CA  1 
ATOM 11380 C C   . LYS D 1 383 ? 0.014   -49.301 27.224  1.00 130.90 ? 383 LYS D C   1 
ATOM 11381 O O   . LYS D 1 383 ? 1.160   -48.862 27.038  1.00 133.22 ? 383 LYS D O   1 
ATOM 11382 C CB  . LYS D 1 383 ? -2.302  -48.338 27.263  1.00 134.28 ? 383 LYS D CB  1 
ATOM 11383 C CG  . LYS D 1 383 ? -2.250  -47.491 25.999  1.00 135.93 ? 383 LYS D CG  1 
ATOM 11384 C CD  . LYS D 1 383 ? -3.431  -47.726 25.083  1.00 141.60 ? 383 LYS D CD  1 
ATOM 11385 C CE  . LYS D 1 383 ? -3.962  -46.459 24.443  1.00 149.21 ? 383 LYS D CE  1 
ATOM 11386 N NZ  . LYS D 1 383 ? -4.560  -45.536 25.438  1.00 147.72 ? 383 LYS D NZ  1 
ATOM 11387 N N   . TYR D 1 384 ? -0.453  -50.451 26.758  1.00 123.78 ? 384 TYR D N   1 
ATOM 11388 C CA  . TYR D 1 384 ? 0.424   -51.362 26.002  1.00 120.35 ? 384 TYR D CA  1 
ATOM 11389 C C   . TYR D 1 384 ? -0.072  -51.431 24.563  1.00 126.60 ? 384 TYR D C   1 
ATOM 11390 O O   . TYR D 1 384 ? -1.151  -50.883 24.269  1.00 124.12 ? 384 TYR D O   1 
ATOM 11391 C CB  . TYR D 1 384 ? 0.329   -52.740 26.644  1.00 122.07 ? 384 TYR D CB  1 
ATOM 11392 C CG  . TYR D 1 384 ? 0.304   -52.726 28.148  1.00 123.65 ? 384 TYR D CG  1 
ATOM 11393 C CD1 . TYR D 1 384 ? 1.439   -52.393 28.860  1.00 126.50 ? 384 TYR D CD1 1 
ATOM 11394 C CD2 . TYR D 1 384 ? -0.836  -53.063 28.858  1.00 114.11 ? 384 TYR D CD2 1 
ATOM 11395 C CE1 . TYR D 1 384 ? 1.448   -52.400 30.242  1.00 124.77 ? 384 TYR D CE1 1 
ATOM 11396 C CE2 . TYR D 1 384 ? -0.848  -53.066 30.242  1.00 109.23 ? 384 TYR D CE2 1 
ATOM 11397 C CZ  . TYR D 1 384 ? 0.301   -52.735 30.933  1.00 116.69 ? 384 TYR D CZ  1 
ATOM 11398 O OH  . TYR D 1 384 ? 0.336   -52.732 32.291  1.00 104.69 ? 384 TYR D OH  1 
ATOM 11399 N N   . LYS D 1 385 ? 0.689   -52.109 23.704  1.00 126.40 ? 385 LYS D N   1 
ATOM 11400 C CA  . LYS D 1 385 ? 0.337   -52.171 22.268  1.00 116.85 ? 385 LYS D CA  1 
ATOM 11401 C C   . LYS D 1 385 ? 0.050   -53.623 21.890  1.00 106.41 ? 385 LYS D C   1 
ATOM 11402 O O   . LYS D 1 385 ? 0.490   -54.506 22.633  1.00 107.79 ? 385 LYS D O   1 
ATOM 11403 C CB  . LYS D 1 385 ? 1.479   -51.556 21.460  1.00 121.60 ? 385 LYS D CB  1 
ATOM 11404 C CG  . LYS D 1 385 ? 1.797   -50.106 21.792  1.00 126.82 ? 385 LYS D CG  1 
ATOM 11405 C CD  . LYS D 1 385 ? 2.718   -49.462 20.782  1.00 132.54 ? 385 LYS D CD  1 
ATOM 11406 C CE  . LYS D 1 385 ? 3.121   -48.053 21.158  1.00 139.69 ? 385 LYS D CE  1 
ATOM 11407 N NZ  . LYS D 1 385 ? 4.459   -47.710 20.622  1.00 141.57 ? 385 LYS D NZ  1 
ATOM 11408 N N   . ARG D 1 386 ? -0.647  -53.853 20.776  1.00 99.33  ? 386 ARG D N   1 
ATOM 11409 C CA  . ARG D 1 386 ? -1.064  -55.223 20.401  1.00 100.28 ? 386 ARG D CA  1 
ATOM 11410 C C   . ARG D 1 386 ? 0.134   -56.163 20.308  1.00 104.57 ? 386 ARG D C   1 
ATOM 11411 O O   . ARG D 1 386 ? 0.009   -57.296 20.774  1.00 107.41 ? 386 ARG D O   1 
ATOM 11412 C CB  . ARG D 1 386 ? -1.735  -55.156 19.030  1.00 111.13 ? 386 ARG D CB  1 
ATOM 11413 C CG  . ARG D 1 386 ? -2.785  -54.061 18.920  1.00 112.32 ? 386 ARG D CG  1 
ATOM 11414 C CD  . ARG D 1 386 ? -2.685  -53.186 17.686  1.00 105.36 ? 386 ARG D CD  1 
ATOM 11415 N NE  . ARG D 1 386 ? -3.920  -52.433 17.530  1.00 108.32 ? 386 ARG D NE  1 
ATOM 11416 C CZ  . ARG D 1 386 ? -4.005  -51.209 17.024  1.00 112.16 ? 386 ARG D CZ  1 
ATOM 11417 N NH1 . ARG D 1 386 ? -2.917  -50.585 16.611  1.00 109.62 ? 386 ARG D NH1 1 
ATOM 11418 N NH2 . ARG D 1 386 ? -5.182  -50.615 16.931  1.00 104.29 ? 386 ARG D NH2 1 
ATOM 11419 N N   . GLU D 1 387 ? 1.223   -55.730 19.681  1.00 102.53 ? 387 GLU D N   1 
ATOM 11420 C CA  . GLU D 1 387 ? 2.439   -56.585 19.652  1.00 104.32 ? 387 GLU D CA  1 
ATOM 11421 C C   . GLU D 1 387 ? 2.790   -57.047 21.070  1.00 104.91 ? 387 GLU D C   1 
ATOM 11422 O O   . GLU D 1 387 ? 2.872   -58.267 21.270  1.00 103.56 ? 387 GLU D O   1 
ATOM 11423 C CB  . GLU D 1 387 ? 3.613   -55.836 19.020  1.00 109.39 ? 387 GLU D CB  1 
ATOM 11424 C CG  . GLU D 1 387 ? 3.820   -56.173 17.555  1.00 115.20 ? 387 GLU D CG  1 
ATOM 11425 C CD  . GLU D 1 387 ? 3.820   -57.657 17.230  1.00 116.90 ? 387 GLU D CD  1 
ATOM 11426 O OE1 . GLU D 1 387 ? 4.747   -58.360 17.679  1.00 117.17 ? 387 GLU D OE1 1 
ATOM 11427 O OE2 . GLU D 1 387 ? 2.899   -58.107 16.520  1.00 110.24 ? 387 GLU D OE2 1 
ATOM 11428 N N   . GLY D 1 388 ? 3.005   -56.112 22.003  1.00 107.54 ? 388 GLY D N   1 
ATOM 11429 C CA  . GLY D 1 388 ? 3.361   -56.472 23.366  1.00 103.70 ? 388 GLY D CA  1 
ATOM 11430 C C   . GLY D 1 388 ? 2.449   -57.523 23.967  1.00 99.45  ? 388 GLY D C   1 
ATOM 11431 O O   . GLY D 1 388 ? 2.889   -58.344 24.777  1.00 99.63  ? 388 GLY D O   1 
ATOM 11432 N N   . ILE D 1 389 ? 1.174   -57.524 23.577  1.00 94.65  ? 389 ILE D N   1 
ATOM 11433 C CA  . ILE D 1 389 ? 0.224   -58.493 24.111  1.00 87.09  ? 389 ILE D CA  1 
ATOM 11434 C C   . ILE D 1 389 ? 0.331   -59.820 23.370  1.00 92.82  ? 389 ILE D C   1 
ATOM 11435 O O   . ILE D 1 389 ? 0.409   -60.891 23.986  1.00 99.77  ? 389 ILE D O   1 
ATOM 11436 C CB  . ILE D 1 389 ? -1.204  -57.923 24.041  1.00 80.43  ? 389 ILE D CB  1 
ATOM 11437 C CG1 . ILE D 1 389 ? -1.320  -56.670 24.910  1.00 83.95  ? 389 ILE D CG1 1 
ATOM 11438 C CG2 . ILE D 1 389 ? -2.223  -58.974 24.454  1.00 84.01  ? 389 ILE D CG2 1 
ATOM 11439 C CD1 . ILE D 1 389 ? -2.704  -56.067 24.932  1.00 83.05  ? 389 ILE D CD1 1 
ATOM 11440 N N   . ALA D 1 390 ? 0.319   -59.762 22.037  1.00 89.74  ? 390 ALA D N   1 
ATOM 11441 C CA  . ALA D 1 390 ? 0.375   -60.979 21.236  1.00 92.33  ? 390 ALA D CA  1 
ATOM 11442 C C   . ALA D 1 390 ? 1.670   -61.743 21.480  1.00 94.53  ? 390 ALA D C   1 
ATOM 11443 O O   . ALA D 1 390 ? 1.664   -62.978 21.555  1.00 93.51  ? 390 ALA D O   1 
ATOM 11444 C CB  . ALA D 1 390 ? 0.225   -60.638 19.754  1.00 98.73  ? 390 ALA D CB  1 
ATOM 11445 N N   . GLU D 1 391 ? 2.790   -61.028 21.602  1.00 95.52  ? 391 GLU D N   1 
ATOM 11446 C CA  . GLU D 1 391 ? 4.067   -61.687 21.847  1.00 96.83  ? 391 GLU D CA  1 
ATOM 11447 C C   . GLU D 1 391 ? 4.016   -62.518 23.121  1.00 101.12 ? 391 GLU D C   1 
ATOM 11448 O O   . GLU D 1 391 ? 4.357   -63.705 23.109  1.00 94.56  ? 391 GLU D O   1 
ATOM 11449 C CB  . GLU D 1 391 ? 5.192   -60.654 21.924  1.00 104.58 ? 391 GLU D CB  1 
ATOM 11450 C CG  . GLU D 1 391 ? 5.715   -60.198 20.568  1.00 104.68 ? 391 GLU D CG  1 
ATOM 11451 C CD  . GLU D 1 391 ? 6.881   -59.237 20.691  1.00 114.90 ? 391 GLU D CD  1 
ATOM 11452 O OE1 . GLU D 1 391 ? 7.437   -59.116 21.801  1.00 118.89 ? 391 GLU D OE1 1 
ATOM 11453 O OE2 . GLU D 1 391 ? 7.238   -58.602 19.676  1.00 114.75 ? 391 GLU D OE2 1 
ATOM 11454 N N   . VAL D 1 392 ? 3.573   -61.916 24.227  1.00 100.17 ? 392 VAL D N   1 
ATOM 11455 C CA  . VAL D 1 392 ? 3.583   -62.639 25.492  1.00 98.47  ? 392 VAL D CA  1 
ATOM 11456 C C   . VAL D 1 392 ? 2.547   -63.757 25.488  1.00 95.63  ? 392 VAL D C   1 
ATOM 11457 O O   . VAL D 1 392 ? 2.789   -64.828 26.061  1.00 95.15  ? 392 VAL D O   1 
ATOM 11458 C CB  . VAL D 1 392 ? 3.388   -61.673 26.677  1.00 98.32  ? 392 VAL D CB  1 
ATOM 11459 C CG1 . VAL D 1 392 ? 4.438   -60.569 26.634  1.00 101.09 ? 392 VAL D CG1 1 
ATOM 11460 C CG2 . VAL D 1 392 ? 1.997   -61.076 26.668  1.00 99.71  ? 392 VAL D CG2 1 
ATOM 11461 N N   . ILE D 1 393 ? 1.402   -63.554 24.828  1.00 90.90  ? 393 ILE D N   1 
ATOM 11462 C CA  . ILE D 1 393 ? 0.409   -64.626 24.750  1.00 92.32  ? 393 ILE D CA  1 
ATOM 11463 C C   . ILE D 1 393 ? 0.992   -65.831 24.022  1.00 96.05  ? 393 ILE D C   1 
ATOM 11464 O O   . ILE D 1 393 ? 0.911   -66.971 24.501  1.00 93.71  ? 393 ILE D O   1 
ATOM 11465 C CB  . ILE D 1 393 ? -0.882  -64.128 24.076  1.00 89.76  ? 393 ILE D CB  1 
ATOM 11466 C CG1 . ILE D 1 393 ? -1.603  -63.135 24.986  1.00 83.06  ? 393 ILE D CG1 1 
ATOM 11467 C CG2 . ILE D 1 393 ? -1.794  -65.302 23.744  1.00 92.23  ? 393 ILE D CG2 1 
ATOM 11468 C CD1 . ILE D 1 393 ? -2.874  -62.580 24.386  1.00 80.63  ? 393 ILE D CD1 1 
ATOM 11469 N N   . ARG D 1 394 ? 1.608   -65.596 22.859  1.00 100.86 ? 394 ARG D N   1 
ATOM 11470 C CA  . ARG D 1 394 ? 2.204   -66.695 22.105  1.00 101.85 ? 394 ARG D CA  1 
ATOM 11471 C C   . ARG D 1 394 ? 3.337   -67.347 22.885  1.00 96.26  ? 394 ARG D C   1 
ATOM 11472 O O   . ARG D 1 394 ? 3.456   -68.577 22.902  1.00 93.25  ? 394 ARG D O   1 
ATOM 11473 C CB  . ARG D 1 394 ? 2.706   -66.198 20.748  1.00 96.45  ? 394 ARG D CB  1 
ATOM 11474 C CG  . ARG D 1 394 ? 1.632   -65.588 19.864  1.00 96.10  ? 394 ARG D CG  1 
ATOM 11475 C CD  . ARG D 1 394 ? 2.214   -65.101 18.544  1.00 108.18 ? 394 ARG D CD  1 
ATOM 11476 N NE  . ARG D 1 394 ? 2.290   -66.162 17.549  1.00 111.38 ? 394 ARG D NE  1 
ATOM 11477 C CZ  . ARG D 1 394 ? 1.373   -66.374 16.611  1.00 106.47 ? 394 ARG D CZ  1 
ATOM 11478 N NH1 . ARG D 1 394 ? 0.301   -65.608 16.509  1.00 102.82 ? 394 ARG D NH1 1 
ATOM 11479 N NH2 . ARG D 1 394 ? 1.542   -67.379 15.756  1.00 102.17 ? 394 ARG D NH2 1 
ATOM 11480 N N   . LYS D 1 395 ? 4.174   -66.539 23.542  1.00 90.14  ? 395 LYS D N   1 
ATOM 11481 C CA  . LYS D 1 395 ? 5.294   -67.085 24.303  1.00 95.48  ? 395 LYS D CA  1 
ATOM 11482 C C   . LYS D 1 395 ? 4.805   -68.004 25.413  1.00 95.62  ? 395 LYS D C   1 
ATOM 11483 O O   . LYS D 1 395 ? 5.326   -69.112 25.590  1.00 104.09 ? 395 LYS D O   1 
ATOM 11484 C CB  . LYS D 1 395 ? 6.140   -65.948 24.881  1.00 97.70  ? 395 LYS D CB  1 
ATOM 11485 C CG  . LYS D 1 395 ? 6.941   -65.167 23.848  1.00 99.35  ? 395 LYS D CG  1 
ATOM 11486 C CD  . LYS D 1 395 ? 7.338   -63.794 24.378  1.00 97.18  ? 395 LYS D CD  1 
ATOM 11487 C CE  . LYS D 1 395 ? 8.616   -63.850 25.198  1.00 89.95  ? 395 LYS D CE  1 
ATOM 11488 N NZ  . LYS D 1 395 ? 9.810   -64.082 24.334  1.00 81.32  ? 395 LYS D NZ  1 
ATOM 11489 N N   . VAL D 1 396 ? 3.791   -67.572 26.160  1.00 94.43  ? 396 VAL D N   1 
ATOM 11490 C CA  . VAL D 1 396 ? 3.343   -68.336 27.319  1.00 98.92  ? 396 VAL D CA  1 
ATOM 11491 C C   . VAL D 1 396 ? 2.551   -69.565 26.888  1.00 91.01  ? 396 VAL D C   1 
ATOM 11492 O O   . VAL D 1 396 ? 2.894   -70.699 27.243  1.00 85.82  ? 396 VAL D O   1 
ATOM 11493 C CB  . VAL D 1 396 ? 2.520   -67.446 28.270  1.00 98.23  ? 396 VAL D CB  1 
ATOM 11494 C CG1 . VAL D 1 396 ? 1.851   -68.292 29.342  1.00 89.80  ? 396 VAL D CG1 1 
ATOM 11495 C CG2 . VAL D 1 396 ? 3.411   -66.390 28.898  1.00 102.22 ? 396 VAL D CG2 1 
ATOM 11496 N N   . VAL D 1 397 ? 1.486   -69.366 26.113  1.00 90.42  ? 397 VAL D N   1 
ATOM 11497 C CA  . VAL D 1 397 ? 0.496   -70.433 25.970  1.00 93.25  ? 397 VAL D CA  1 
ATOM 11498 C C   . VAL D 1 397 ? 0.902   -71.451 24.908  1.00 92.65  ? 397 VAL D C   1 
ATOM 11499 O O   . VAL D 1 397 ? 0.674   -72.653 25.074  1.00 93.98  ? 397 VAL D O   1 
ATOM 11500 C CB  . VAL D 1 397 ? -0.892  -69.836 25.679  1.00 91.16  ? 397 VAL D CB  1 
ATOM 11501 C CG1 . VAL D 1 397 ? -1.954  -70.930 25.705  1.00 84.71  ? 397 VAL D CG1 1 
ATOM 11502 C CG2 . VAL D 1 397 ? -1.223  -68.748 26.695  1.00 94.08  ? 397 VAL D CG2 1 
ATOM 11503 N N   . VAL D 1 398 ? 1.510   -71.008 23.809  1.00 90.39  ? 398 VAL D N   1 
ATOM 11504 C CA  . VAL D 1 398 ? 1.681   -71.860 22.633  1.00 96.99  ? 398 VAL D CA  1 
ATOM 11505 C C   . VAL D 1 398 ? 3.137   -72.070 22.235  1.00 100.72 ? 398 VAL D C   1 
ATOM 11506 O O   . VAL D 1 398 ? 3.408   -72.938 21.392  1.00 103.54 ? 398 VAL D O   1 
ATOM 11507 C CB  . VAL D 1 398 ? 0.881   -71.307 21.432  1.00 97.30  ? 398 VAL D CB  1 
ATOM 11508 C CG1 . VAL D 1 398 ? 1.663   -70.223 20.711  1.00 91.94  ? 398 VAL D CG1 1 
ATOM 11509 C CG2 . VAL D 1 398 ? 0.476   -72.425 20.483  1.00 96.89  ? 398 VAL D CG2 1 
ATOM 11510 N N   . GLU D 1 399 ? 4.085   -71.325 22.796  1.00 95.87  ? 399 GLU D N   1 
ATOM 11511 C CA  . GLU D 1 399 ? 5.477   -71.425 22.383  1.00 95.53  ? 399 GLU D CA  1 
ATOM 11512 C C   . GLU D 1 399 ? 6.288   -72.228 23.393  1.00 100.60 ? 399 GLU D C   1 
ATOM 11513 O O   . GLU D 1 399 ? 5.906   -72.382 24.555  1.00 101.31 ? 399 GLU D O   1 
ATOM 11514 C CB  . GLU D 1 399 ? 6.091   -70.032 22.203  1.00 89.54  ? 399 GLU D CB  1 
ATOM 11515 C CG  . GLU D 1 399 ? 6.947   -69.878 20.948  1.00 103.20 ? 399 GLU D CG  1 
ATOM 11516 C CD  . GLU D 1 399 ? 8.336   -70.467 21.104  1.00 110.79 ? 399 GLU D CD  1 
ATOM 11517 O OE1 . GLU D 1 399 ? 8.803   -70.585 22.255  1.00 108.80 ? 399 GLU D OE1 1 
ATOM 11518 O OE2 . GLU D 1 399 ? 8.960   -70.814 20.076  1.00 117.32 ? 399 GLU D OE2 1 
ATOM 11519 N N   . LYS D 1 400 ? 7.430   -72.740 22.927  1.00 100.77 ? 400 LYS D N   1 
ATOM 11520 C CA  . LYS D 1 400 ? 8.307   -73.514 23.800  1.00 104.39 ? 400 LYS D CA  1 
ATOM 11521 C C   . LYS D 1 400 ? 8.981   -72.640 24.851  1.00 103.34 ? 400 LYS D C   1 
ATOM 11522 O O   . LYS D 1 400 ? 9.268   -73.117 25.954  1.00 101.83 ? 400 LYS D O   1 
ATOM 11523 C CB  . LYS D 1 400 ? 9.372   -74.241 22.978  1.00 104.42 ? 400 LYS D CB  1 
ATOM 11524 C CG  . LYS D 1 400 ? 8.829   -75.303 22.041  1.00 110.50 ? 400 LYS D CG  1 
ATOM 11525 C CD  . LYS D 1 400 ? 9.959   -76.016 21.306  1.00 109.09 ? 400 LYS D CD  1 
ATOM 11526 C CE  . LYS D 1 400 ? 9.431   -77.137 20.425  1.00 110.61 ? 400 LYS D CE  1 
ATOM 11527 N NZ  . LYS D 1 400 ? 10.530  -77.823 19.688  1.00 117.81 ? 400 LYS D NZ  1 
ATOM 11528 N N   . SER D 1 401 ? 9.249   -71.371 24.528  1.00 104.22 ? 401 SER D N   1 
ATOM 11529 C CA  . SER D 1 401 ? 9.927   -70.484 25.471  1.00 94.96  ? 401 SER D CA  1 
ATOM 11530 C C   . SER D 1 401 ? 9.139   -70.299 26.760  1.00 95.47  ? 401 SER D C   1 
ATOM 11531 O O   . SER D 1 401 ? 9.732   -69.980 27.798  1.00 85.13  ? 401 SER D O   1 
ATOM 11532 C CB  . SER D 1 401 ? 10.187  -69.124 24.822  1.00 90.33  ? 401 SER D CB  1 
ATOM 11533 O OG  . SER D 1 401 ? 8.970   -68.476 24.498  1.00 90.66  ? 401 SER D OG  1 
ATOM 11534 N N   . GLY D 1 402 ? 7.825   -70.495 26.723  1.00 99.03  ? 402 GLY D N   1 
ATOM 11535 C CA  . GLY D 1 402 ? 6.990   -70.415 27.900  1.00 90.29  ? 402 GLY D CA  1 
ATOM 11536 C C   . GLY D 1 402 ? 6.793   -71.721 28.632  1.00 90.14  ? 402 GLY D C   1 
ATOM 11537 O O   . GLY D 1 402 ? 6.021   -71.762 29.597  1.00 91.20  ? 402 GLY D O   1 
ATOM 11538 N N   . GLU D 1 403 ? 7.468   -72.797 28.205  1.00 92.68  ? 403 GLU D N   1 
ATOM 11539 C CA  . GLU D 1 403 ? 7.340   -74.073 28.904  1.00 97.34  ? 403 GLU D CA  1 
ATOM 11540 C C   . GLU D 1 403 ? 7.764   -73.941 30.363  1.00 101.67 ? 403 GLU D C   1 
ATOM 11541 O O   . GLU D 1 403 ? 7.107   -74.482 31.260  1.00 102.69 ? 403 GLU D O   1 
ATOM 11542 C CB  . GLU D 1 403 ? 8.159   -75.145 28.190  1.00 98.64  ? 403 GLU D CB  1 
ATOM 11543 C CG  . GLU D 1 403 ? 7.585   -76.548 28.327  1.00 101.24 ? 403 GLU D CG  1 
ATOM 11544 C CD  . GLU D 1 403 ? 8.382   -77.422 29.275  1.00 102.14 ? 403 GLU D CD  1 
ATOM 11545 O OE1 . GLU D 1 403 ? 9.606   -77.200 29.403  1.00 101.60 ? 403 GLU D OE1 1 
ATOM 11546 O OE2 . GLU D 1 403 ? 7.787   -78.332 29.892  1.00 100.13 ? 403 GLU D OE2 1 
ATOM 11547 N N   . VAL D 1 404 ? 8.824   -73.185 30.608  1.00 95.96  ? 404 VAL D N   1 
ATOM 11548 C CA  . VAL D 1 404 ? 9.208   -72.960 32.026  1.00 95.78  ? 404 VAL D CA  1 
ATOM 11549 C C   . VAL D 1 404 ? 7.958   -72.497 32.775  1.00 99.63  ? 404 VAL D C   1 
ATOM 11550 O O   . VAL D 1 404 ? 7.568   -73.182 33.750  1.00 100.69 ? 404 VAL D O   1 
ATOM 11551 C CB  . VAL D 1 404 ? 10.361  -71.949 32.146  1.00 95.65  ? 404 VAL D CB  1 
ATOM 11552 C CG1 . VAL D 1 404 ? 10.710  -71.664 33.598  1.00 92.67  ? 404 VAL D CG1 1 
ATOM 11553 C CG2 . VAL D 1 404 ? 11.590  -72.417 31.382  1.00 96.11  ? 404 VAL D CG2 1 
ATOM 11554 N N   . ILE D 1 405 ? 7.276   -71.469 32.269  1.00 96.37  ? 405 ILE D N   1 
ATOM 11555 C CA  . ILE D 1 405 ? 6.130   -70.886 33.023  1.00 93.05  ? 405 ILE D CA  1 
ATOM 11556 C C   . ILE D 1 405 ? 5.035   -71.937 33.238  1.00 90.36  ? 405 ILE D C   1 
ATOM 11557 O O   . ILE D 1 405 ? 4.546   -72.082 34.386  1.00 92.97  ? 405 ILE D O   1 
ATOM 11558 C CB  . ILE D 1 405 ? 5.641   -69.651 32.247  1.00 93.07  ? 405 ILE D CB  1 
ATOM 11559 C CG1 . ILE D 1 405 ? 6.757   -68.619 32.089  1.00 81.88  ? 405 ILE D CG1 1 
ATOM 11560 C CG2 . ILE D 1 405 ? 4.398   -69.047 32.872  1.00 85.70  ? 405 ILE D CG2 1 
ATOM 11561 C CD1 . ILE D 1 405 ? 6.406   -67.473 31.177  1.00 82.07  ? 405 ILE D CD1 1 
ATOM 11562 N N   . ARG D 1 406 ? 4.708   -72.690 32.196  1.00 82.95  ? 406 ARG D N   1 
ATOM 11563 C CA  . ARG D 1 406 ? 3.598   -73.664 32.296  1.00 90.21  ? 406 ARG D CA  1 
ATOM 11564 C C   . ARG D 1 406 ? 3.946   -74.767 33.288  1.00 91.65  ? 406 ARG D C   1 
ATOM 11565 O O   . ARG D 1 406 ? 3.072   -75.146 34.144  1.00 99.52  ? 406 ARG D O   1 
ATOM 11566 C CB  . ARG D 1 406 ? 3.316   -74.208 30.896  1.00 97.36  ? 406 ARG D CB  1 
ATOM 11567 C CG  . ARG D 1 406 ? 2.908   -73.144 29.886  1.00 92.45  ? 406 ARG D CG  1 
ATOM 11568 C CD  . ARG D 1 406 ? 2.384   -73.750 28.600  1.00 79.97  ? 406 ARG D CD  1 
ATOM 11569 N NE  . ARG D 1 406 ? 3.385   -74.556 27.920  1.00 79.08  ? 406 ARG D NE  1 
ATOM 11570 C CZ  . ARG D 1 406 ? 4.054   -74.176 26.840  1.00 87.49  ? 406 ARG D CZ  1 
ATOM 11571 N NH1 . ARG D 1 406 ? 3.815   -73.000 26.294  1.00 86.89  ? 406 ARG D NH1 1 
ATOM 11572 N NH2 . ARG D 1 406 ? 4.949   -74.982 26.299  1.00 84.70  ? 406 ARG D NH2 1 
ATOM 11573 N N   . ARG D 1 407 ? 5.168   -75.299 33.193  1.00 89.52  ? 407 ARG D N   1 
ATOM 11574 C CA  . ARG D 1 407 ? 5.608   -76.392 34.102  1.00 97.82  ? 407 ARG D CA  1 
ATOM 11575 C C   . ARG D 1 407 ? 5.466   -75.925 35.553  1.00 97.61  ? 407 ARG D C   1 
ATOM 11576 O O   . ARG D 1 407 ? 4.906   -76.687 36.364  1.00 102.37 ? 407 ARG D O   1 
ATOM 11577 C CB  . ARG D 1 407 ? 7.053   -76.782 33.787  1.00 95.51  ? 407 ARG D CB  1 
ATOM 11578 C CG  . ARG D 1 407 ? 7.643   -77.823 34.726  1.00 96.76  ? 407 ARG D CG  1 
ATOM 11579 C CD  . ARG D 1 407 ? 9.098   -78.143 34.435  1.00 99.52  ? 407 ARG D CD  1 
ATOM 11580 N NE  . ARG D 1 407 ? 10.002  -77.021 34.645  1.00 102.39 ? 407 ARG D NE  1 
ATOM 11581 C CZ  . ARG D 1 407 ? 10.516  -76.267 33.679  1.00 99.52  ? 407 ARG D CZ  1 
ATOM 11582 N NH1 . ARG D 1 407 ? 10.222  -76.516 32.413  1.00 102.16 ? 407 ARG D NH1 1 
ATOM 11583 N NH2 . ARG D 1 407 ? 11.329  -75.271 33.981  1.00 94.55  ? 407 ARG D NH2 1 
ATOM 11584 N N   . LYS D 1 408 ? 5.924   -74.708 35.836  1.00 88.73  ? 408 LYS D N   1 
ATOM 11585 C CA  . LYS D 1 408 ? 5.901   -74.185 37.221  1.00 96.90  ? 408 LYS D CA  1 
ATOM 11586 C C   . LYS D 1 408 ? 4.463   -74.047 37.708  1.00 94.13  ? 408 LYS D C   1 
ATOM 11587 O O   . LYS D 1 408 ? 4.211   -74.383 38.868  1.00 92.55  ? 408 LYS D O   1 
ATOM 11588 C CB  . LYS D 1 408 ? 6.601   -72.828 37.273  1.00 92.18  ? 408 LYS D CB  1 
ATOM 11589 C CG  . LYS D 1 408 ? 8.069   -72.821 36.870  1.00 94.02  ? 408 LYS D CG  1 
ATOM 11590 C CD  . LYS D 1 408 ? 8.974   -73.634 37.774  1.00 97.96  ? 408 LYS D CD  1 
ATOM 11591 C CE  . LYS D 1 408 ? 10.433  -73.547 37.377  1.00 93.24  ? 408 LYS D CE  1 
ATOM 11592 N NZ  . LYS D 1 408 ? 11.309  -74.319 38.289  1.00 85.04  ? 408 LYS D NZ  1 
ATOM 11593 N N   . ALA D 1 409 ? 3.569   -73.563 36.857  1.00 90.29  ? 409 ALA D N   1 
ATOM 11594 C CA  . ALA D 1 409 ? 2.155   -73.346 37.243  1.00 89.66  ? 409 ALA D CA  1 
ATOM 11595 C C   . ALA D 1 409 ? 1.534   -74.675 37.691  1.00 95.02  ? 409 ALA D C   1 
ATOM 11596 O O   . ALA D 1 409 ? 0.832   -74.676 38.720  1.00 98.82  ? 409 ALA D O   1 
ATOM 11597 C CB  . ALA D 1 409 ? 1.392   -72.734 36.096  1.00 90.19  ? 409 ALA D CB  1 
ATOM 11598 N N   . ARG D 1 410 ? 1.792   -75.757 36.950  1.00 100.32 ? 410 ARG D N   1 
ATOM 11599 C CA  . ARG D 1 410 ? 1.221   -77.082 37.277  1.00 105.29 ? 410 ARG D CA  1 
ATOM 11600 C C   . ARG D 1 410 ? 1.859   -77.620 38.547  1.00 103.24 ? 410 ARG D C   1 
ATOM 11601 O O   . ARG D 1 410 ? 1.131   -78.138 39.373  1.00 99.50  ? 410 ARG D O   1 
ATOM 11602 C CB  . ARG D 1 410 ? 1.556   -78.077 36.165  1.00 107.15 ? 410 ARG D CB  1 
ATOM 11603 C CG  . ARG D 1 410 ? 0.952   -79.462 36.349  1.00 115.27 ? 410 ARG D CG  1 
ATOM 11604 C CD  . ARG D 1 410 ? 1.975   -80.574 36.223  1.00 126.70 ? 410 ARG D CD  1 
ATOM 11605 N NE  . ARG D 1 410 ? 1.357   -81.850 35.894  1.00 136.77 ? 410 ARG D NE  1 
ATOM 11606 C CZ  . ARG D 1 410 ? 2.006   -83.005 35.794  1.00 135.20 ? 410 ARG D CZ  1 
ATOM 11607 N NH1 . ARG D 1 410 ? 3.308   -83.055 36.014  1.00 131.56 ? 410 ARG D NH1 1 
ATOM 11608 N NH2 . ARG D 1 410 ? 1.348   -84.105 35.481  1.00 131.91 ? 410 ARG D NH2 1 
ATOM 11609 N N   . GLU D 1 411 ? 3.177   -77.504 38.677  1.00 100.02 ? 411 GLU D N   1 
ATOM 11610 C CA  . GLU D 1 411 ? 3.875   -78.074 39.851  1.00 102.32 ? 411 GLU D CA  1 
ATOM 11611 C C   . GLU D 1 411 ? 3.395   -77.340 41.104  1.00 94.24  ? 411 GLU D C   1 
ATOM 11612 O O   . GLU D 1 411 ? 3.075   -77.998 42.113  1.00 97.45  ? 411 GLU D O   1 
ATOM 11613 C CB  . GLU D 1 411 ? 5.384   -78.009 39.624  1.00 94.97  ? 411 GLU D CB  1 
ATOM 11614 C CG  . GLU D 1 411 ? 5.898   -79.119 38.730  1.00 92.96  ? 411 GLU D CG  1 
ATOM 11615 C CD  . GLU D 1 411 ? 7.373   -79.020 38.387  1.00 95.47  ? 411 GLU D CD  1 
ATOM 11616 O OE1 . GLU D 1 411 ? 7.955   -77.945 38.611  1.00 95.16  ? 411 GLU D OE1 1 
ATOM 11617 O OE2 . GLU D 1 411 ? 7.936   -80.019 37.898  1.00 93.24  ? 411 GLU D OE2 1 
ATOM 11618 N N   . LEU D 1 412 ? 3.273   -76.024 41.003  1.00 86.23  ? 412 LEU D N   1 
ATOM 11619 C CA  . LEU D 1 412 ? 2.809   -75.233 42.164  1.00 85.24  ? 412 LEU D CA  1 
ATOM 11620 C C   . LEU D 1 412 ? 1.360   -75.595 42.495  1.00 82.52  ? 412 LEU D C   1 
ATOM 11621 O O   . LEU D 1 412 ? 1.041   -75.613 43.678  1.00 82.20  ? 412 LEU D O   1 
ATOM 11622 C CB  . LEU D 1 412 ? 3.035   -73.745 41.895  1.00 86.54  ? 412 LEU D CB  1 
ATOM 11623 C CG  . LEU D 1 412 ? 4.494   -73.303 41.966  1.00 90.38  ? 412 LEU D CG  1 
ATOM 11624 C CD1 . LEU D 1 412 ? 4.595   -71.806 42.186  1.00 85.31  ? 412 LEU D CD1 1 
ATOM 11625 C CD2 . LEU D 1 412 ? 5.230   -74.037 43.076  1.00 84.72  ? 412 LEU D CD2 1 
ATOM 11626 N N   . SER D 1 413 ? 0.521   -75.846 41.489  1.00 83.31  ? 413 SER D N   1 
ATOM 11627 C CA  . SER D 1 413 ? -0.898  -76.239 41.698  1.00 92.35  ? 413 SER D CA  1 
ATOM 11628 C C   . SER D 1 413 ? -0.947  -77.580 42.410  1.00 86.87  ? 413 SER D C   1 
ATOM 11629 O O   . SER D 1 413 ? -1.740  -77.737 43.348  1.00 85.72  ? 413 SER D O   1 
ATOM 11630 C CB  . SER D 1 413 ? -1.626  -76.319 40.393  1.00 89.61  ? 413 SER D CB  1 
ATOM 11631 O OG  . SER D 1 413 ? -2.933  -76.837 40.575  1.00 98.48  ? 413 SER D OG  1 
ATOM 11632 N N   . GLU D 1 414 ? -0.075  -78.489 41.994  1.00 86.79  ? 414 GLU D N   1 
ATOM 11633 C CA  . GLU D 1 414 ? -0.024  -79.816 42.631  1.00 92.56  ? 414 GLU D CA  1 
ATOM 11634 C C   . GLU D 1 414 ? 0.356   -79.601 44.087  1.00 93.37  ? 414 GLU D C   1 
ATOM 11635 O O   . GLU D 1 414 ? -0.258  -80.232 44.928  1.00 89.62  ? 414 GLU D O   1 
ATOM 11636 C CB  . GLU D 1 414 ? 0.997   -80.697 41.917  1.00 99.24  ? 414 GLU D CB  1 
ATOM 11637 C CG  . GLU D 1 414 ? 0.517   -81.211 40.576  1.00 105.71 ? 414 GLU D CG  1 
ATOM 11638 C CD  . GLU D 1 414 ? 1.550   -82.014 39.810  1.00 118.31 ? 414 GLU D CD  1 
ATOM 11639 O OE1 . GLU D 1 414 ? 2.752   -81.746 39.983  1.00 119.32 ? 414 GLU D OE1 1 
ATOM 11640 O OE2 . GLU D 1 414 ? 1.147   -82.915 39.051  1.00 121.38 ? 414 GLU D OE2 1 
ATOM 11641 N N   . LYS D 1 415 ? 1.314   -78.715 44.350  1.00 90.71  ? 415 LYS D N   1 
ATOM 11642 C CA  . LYS D 1 415 ? 1.763   -78.487 45.744  1.00 85.43  ? 415 LYS D CA  1 
ATOM 11643 C C   . LYS D 1 415 ? 0.615   -77.900 46.553  1.00 82.76  ? 415 LYS D C   1 
ATOM 11644 O O   . LYS D 1 415 ? 0.400   -78.348 47.680  1.00 84.92  ? 415 LYS D O   1 
ATOM 11645 C CB  . LYS D 1 415 ? 2.943   -77.523 45.790  1.00 75.48  ? 415 LYS D CB  1 
ATOM 11646 C CG  . LYS D 1 415 ? 4.313   -78.150 45.581  1.00 78.92  ? 415 LYS D CG  1 
ATOM 11647 C CD  . LYS D 1 415 ? 5.378   -77.139 45.225  1.00 83.95  ? 415 LYS D CD  1 
ATOM 11648 C CE  . LYS D 1 415 ? 6.758   -77.751 45.150  1.00 68.43  ? 415 LYS D CE  1 
ATOM 11649 N NZ  . LYS D 1 415 ? 6.747   -79.021 44.386  1.00 71.90  ? 415 LYS D NZ  1 
ATOM 11650 N N   . MET D 1 416 ? -0.109  -76.955 45.978  1.00 76.26  ? 416 MET D N   1 
ATOM 11651 C CA  . MET D 1 416 ? -1.169  -76.266 46.742  1.00 78.59  ? 416 MET D CA  1 
ATOM 11652 C C   . MET D 1 416 ? -2.213  -77.310 47.104  1.00 84.66  ? 416 MET D C   1 
ATOM 11653 O O   . MET D 1 416 ? -2.842  -77.174 48.158  1.00 86.13  ? 416 MET D O   1 
ATOM 11654 C CB  . MET D 1 416 ? -1.764  -75.137 45.900  1.00 71.09  ? 416 MET D CB  1 
ATOM 11655 C CG  . MET D 1 416 ? -0.823  -73.964 45.732  1.00 77.73  ? 416 MET D CG  1 
ATOM 11656 S SD  . MET D 1 416 ? -1.411  -72.789 44.500  1.00 75.88  ? 416 MET D SD  1 
ATOM 11657 C CE  . MET D 1 416 ? -2.962  -72.296 45.244  1.00 64.21  ? 416 MET D CE  1 
ATOM 11658 N N   . LYS D 1 417 ? -2.371  -78.314 46.259  1.00 80.45  ? 417 LYS D N   1 
ATOM 11659 C CA  . LYS D 1 417 ? -3.267  -79.413 46.578  1.00 82.32  ? 417 LYS D CA  1 
ATOM 11660 C C   . LYS D 1 417 ? -2.560  -80.594 47.224  1.00 78.42  ? 417 LYS D C   1 
ATOM 11661 O O   . LYS D 1 417 ? -3.232  -81.455 47.804  1.00 72.42  ? 417 LYS D O   1 
ATOM 11662 C CB  . LYS D 1 417 ? -3.999  -79.888 45.317  1.00 91.21  ? 417 LYS D CB  1 
ATOM 11663 C CG  . LYS D 1 417 ? -4.889  -78.829 44.685  1.00 91.42  ? 417 LYS D CG  1 
ATOM 11664 C CD  . LYS D 1 417 ? -5.958  -78.347 45.661  1.00 94.96  ? 417 LYS D CD  1 
ATOM 11665 C CE  . LYS D 1 417 ? -6.901  -79.475 46.062  1.00 97.73  ? 417 LYS D CE  1 
ATOM 11666 N NZ  . LYS D 1 417 ? -7.965  -79.012 46.996  1.00 109.39 ? 417 LYS D NZ  1 
ATOM 11667 N N   . GLU D 1 418 ? -1.229  -80.654 47.147  1.00 82.27  ? 418 GLU D N   1 
ATOM 11668 C CA  . GLU D 1 418 ? -0.502  -81.745 47.786  1.00 80.27  ? 418 GLU D CA  1 
ATOM 11669 C C   . GLU D 1 418 ? -0.444  -81.553 49.298  1.00 77.95  ? 418 GLU D C   1 
ATOM 11670 O O   . GLU D 1 418 ? -0.705  -82.489 50.061  1.00 85.56  ? 418 GLU D O   1 
ATOM 11671 C CB  . GLU D 1 418 ? 0.902   -81.860 47.191  1.00 74.95  ? 418 GLU D CB  1 
ATOM 11672 C CG  . GLU D 1 418 ? 1.553   -83.215 47.401  1.00 74.58  ? 418 GLU D CG  1 
ATOM 11673 C CD  . GLU D 1 418 ? 2.689   -83.472 46.428  1.00 91.47  ? 418 GLU D CD  1 
ATOM 11674 O OE1 . GLU D 1 418 ? 3.083   -82.530 45.708  1.00 101.82 ? 418 GLU D OE1 1 
ATOM 11675 O OE2 . GLU D 1 418 ? 3.184   -84.618 46.383  1.00 89.46  ? 418 GLU D OE2 1 
ATOM 11676 N N   . LYS D 1 419 ? -0.315  -80.295 49.731  1.00 75.02  ? 419 LYS D N   1 
ATOM 11677 C CA  . LYS D 1 419 ? -0.358  -79.978 51.186  1.00 81.91  ? 419 LYS D CA  1 
ATOM 11678 C C   . LYS D 1 419 ? -1.771  -79.516 51.539  1.00 85.90  ? 419 LYS D C   1 
ATOM 11679 O O   . LYS D 1 419 ? -1.905  -78.580 52.342  1.00 89.88  ? 419 LYS D O   1 
ATOM 11680 C CB  . LYS D 1 419 ? 0.662   -78.885 51.513  1.00 86.34  ? 419 LYS D CB  1 
ATOM 11681 C CG  . LYS D 1 419 ? 0.511   -77.580 50.740  1.00 80.96  ? 419 LYS D CG  1 
ATOM 11682 C CD  . LYS D 1 419 ? 1.401   -76.474 51.257  1.00 87.15  ? 419 LYS D CD  1 
ATOM 11683 C CE  . LYS D 1 419 ? 0.855   -75.095 50.962  1.00 86.64  ? 419 LYS D CE  1 
ATOM 11684 N NZ  . LYS D 1 419 ? 0.573   -74.914 49.520  1.00 86.02  ? 419 LYS D NZ  1 
ATOM 11685 N N   . GLY D 1 420 ? -2.787  -80.193 51.014  1.00 81.23  ? 420 GLY D N   1 
ATOM 11686 C CA  . GLY D 1 420 ? -4.174  -79.718 51.174  1.00 77.41  ? 420 GLY D CA  1 
ATOM 11687 C C   . GLY D 1 420 ? -4.800  -79.837 52.541  1.00 86.00  ? 420 GLY D C   1 
ATOM 11688 O O   . GLY D 1 420 ? -4.541  -80.856 53.193  1.00 95.61  ? 420 GLY D O   1 
ATOM 11689 N N   . GLU D 1 421 ? -5.522  -78.803 52.983  1.00 73.43  ? 421 GLU D N   1 
ATOM 11690 C CA  . GLU D 1 421 ? -6.319  -78.828 54.242  1.00 69.74  ? 421 GLU D CA  1 
ATOM 11691 C C   . GLU D 1 421 ? -5.464  -78.592 55.484  1.00 73.34  ? 421 GLU D C   1 
ATOM 11692 O O   . GLU D 1 421 ? -5.995  -78.072 56.461  1.00 67.58  ? 421 GLU D O   1 
ATOM 11693 C CB  . GLU D 1 421 ? -7.217  -80.064 54.343  1.00 81.48  ? 421 GLU D CB  1 
ATOM 11694 C CG  . GLU D 1 421 ? -8.274  -80.152 53.253  1.00 80.85  ? 421 GLU D CG  1 
ATOM 11695 C CD  . GLU D 1 421 ? -9.429  -79.159 53.285  1.00 92.76  ? 421 GLU D CD  1 
ATOM 11696 O OE1 . GLU D 1 421 ? -9.207  -77.980 53.619  1.00 85.40  ? 421 GLU D OE1 1 
ATOM 11697 O OE2 . GLU D 1 421 ? -10.555 -79.567 52.949  1.00 98.63  ? 421 GLU D OE2 1 
ATOM 11698 N N   . GLN D 1 422 ? -4.174  -78.870 55.397  1.00 79.52  ? 422 GLN D N   1 
ATOM 11699 C CA  . GLN D 1 422 ? -3.287  -78.720 56.570  1.00 75.83  ? 422 GLN D CA  1 
ATOM 11700 C C   . GLN D 1 422 ? -3.174  -77.252 56.957  1.00 69.26  ? 422 GLN D C   1 
ATOM 11701 O O   . GLN D 1 422 ? -3.164  -76.982 58.151  1.00 69.39  ? 422 GLN D O   1 
ATOM 11702 C CB  . GLN D 1 422 ? -1.897  -79.275 56.283  1.00 77.47  ? 422 GLN D CB  1 
ATOM 11703 C CG  . GLN D 1 422 ? -1.896  -80.503 55.382  1.00 84.63  ? 422 GLN D CG  1 
ATOM 11704 C CD  . GLN D 1 422 ? -2.544  -81.710 56.013  1.00 92.66  ? 422 GLN D CD  1 
ATOM 11705 O OE1 . GLN D 1 422 ? -2.554  -81.870 57.232  1.00 91.03  ? 422 GLN D OE1 1 
ATOM 11706 N NE2 . GLN D 1 422 ? -3.083  -82.582 55.177  1.00 83.04  ? 422 GLN D NE2 1 
ATOM 11707 N N   . GLU D 1 423 ? -3.075  -76.347 55.987  1.00 65.40  ? 423 GLU D N   1 
ATOM 11708 C CA  . GLU D 1 423 ? -2.817  -74.931 56.351  1.00 65.01  ? 423 GLU D CA  1 
ATOM 11709 C C   . GLU D 1 423 ? -3.963  -74.354 57.172  1.00 57.73  ? 423 GLU D C   1 
ATOM 11710 O O   . GLU D 1 423 ? -3.676  -73.725 58.190  1.00 50.32  ? 423 GLU D O   1 
ATOM 11711 C CB  . GLU D 1 423 ? -2.474  -74.101 55.112  1.00 64.24  ? 423 GLU D CB  1 
ATOM 11712 C CG  . GLU D 1 423 ? -3.098  -74.588 53.815  1.00 74.18  ? 423 GLU D CG  1 
ATOM 11713 C CD  . GLU D 1 423 ? -2.643  -73.812 52.587  1.00 84.52  ? 423 GLU D CD  1 
ATOM 11714 O OE1 . GLU D 1 423 ? -1.720  -72.983 52.720  1.00 82.30  ? 423 GLU D OE1 1 
ATOM 11715 O OE2 . GLU D 1 423 ? -3.208  -74.039 51.496  1.00 72.63  ? 423 GLU D OE2 1 
ATOM 11716 N N   . ILE D 1 424 ? -5.197  -74.581 56.751  1.00 59.07  ? 424 ILE D N   1 
ATOM 11717 C CA  . ILE D 1 424 ? -6.380  -74.136 57.537  1.00 63.03  ? 424 ILE D CA  1 
ATOM 11718 C C   . ILE D 1 424 ? -6.473  -74.956 58.825  1.00 62.40  ? 424 ILE D C   1 
ATOM 11719 O O   . ILE D 1 424 ? -6.912  -74.407 59.835  1.00 57.87  ? 424 ILE D O   1 
ATOM 11720 C CB  . ILE D 1 424 ? -7.653  -74.154 56.677  1.00 61.99  ? 424 ILE D CB  1 
ATOM 11721 C CG1 . ILE D 1 424 ? -7.371  -73.598 55.280  1.00 67.81  ? 424 ILE D CG1 1 
ATOM 11722 C CG2 . ILE D 1 424 ? -8.779  -73.398 57.358  1.00 56.93  ? 424 ILE D CG2 1 
ATOM 11723 C CD1 . ILE D 1 424 ? -8.608  -73.356 54.457  1.00 65.63  ? 424 ILE D CD1 1 
ATOM 11724 N N   . ASP D 1 425 ? -6.095  -76.232 58.778  1.00 64.08  ? 425 ASP D N   1 
ATOM 11725 C CA  . ASP D 1 425 ? -6.093  -77.078 59.997  1.00 52.46  ? 425 ASP D CA  1 
ATOM 11726 C C   . ASP D 1 425 ? -5.102  -76.521 61.019  1.00 56.67  ? 425 ASP D C   1 
ATOM 11727 O O   . ASP D 1 425 ? -5.462  -76.451 62.198  1.00 59.34  ? 425 ASP D O   1 
ATOM 11728 C CB  . ASP D 1 425 ? -5.718  -78.517 59.652  1.00 60.52  ? 425 ASP D CB  1 
ATOM 11729 C CG  . ASP D 1 425 ? -6.841  -79.341 59.050  1.00 70.79  ? 425 ASP D CG  1 
ATOM 11730 O OD1 . ASP D 1 425 ? -7.871  -78.754 58.692  1.00 78.48  ? 425 ASP D OD1 1 
ATOM 11731 O OD2 . ASP D 1 425 ? -6.664  -80.567 58.939  1.00 82.21  ? 425 ASP D OD2 1 
ATOM 11732 N N   . ARG D 1 426 ? -3.903  -76.154 60.580  1.00 58.26  ? 426 ARG D N   1 
ATOM 11733 C CA  . ARG D 1 426 ? -2.891  -75.539 61.474  1.00 57.44  ? 426 ARG D CA  1 
ATOM 11734 C C   . ARG D 1 426 ? -3.384  -74.176 61.950  1.00 58.82  ? 426 ARG D C   1 
ATOM 11735 O O   . ARG D 1 426 ? -3.044  -73.783 63.069  1.00 59.84  ? 426 ARG D O   1 
ATOM 11736 C CB  . ARG D 1 426 ? -1.547  -75.469 60.749  1.00 57.68  ? 426 ARG D CB  1 
ATOM 11737 C CG  . ARG D 1 426 ? -0.944  -76.831 60.440  1.00 71.66  ? 426 ARG D CG  1 
ATOM 11738 C CD  . ARG D 1 426 ? 0.441   -76.731 59.836  1.00 73.41  ? 426 ARG D CD  1 
ATOM 11739 N NE  . ARG D 1 426 ? 0.499   -75.686 58.825  1.00 83.00  ? 426 ARG D NE  1 
ATOM 11740 C CZ  . ARG D 1 426 ? 1.580   -75.379 58.122  1.00 81.18  ? 426 ARG D CZ  1 
ATOM 11741 N NH1 . ARG D 1 426 ? 2.706   -76.045 58.317  1.00 87.09  ? 426 ARG D NH1 1 
ATOM 11742 N NH2 . ARG D 1 426 ? 1.533   -74.407 57.227  1.00 75.17  ? 426 ARG D NH2 1 
ATOM 11743 N N   . ALA D 1 427 ? -4.078  -73.444 61.084  1.00 56.57  ? 427 ALA D N   1 
ATOM 11744 C CA  . ALA D 1 427 ? -4.642  -72.132 61.459  1.00 49.50  ? 427 ALA D CA  1 
ATOM 11745 C C   . ALA D 1 427 ? -5.685  -72.336 62.544  1.00 58.45  ? 427 ALA D C   1 
ATOM 11746 O O   . ALA D 1 427 ? -5.707  -71.550 63.490  1.00 59.61  ? 427 ALA D O   1 
ATOM 11747 C CB  . ALA D 1 427 ? -5.280  -71.511 60.257  1.00 57.13  ? 427 ALA D CB  1 
ATOM 11748 N N   . VAL D 1 428 ? -6.519  -73.362 62.391  1.00 57.98  ? 428 VAL D N   1 
ATOM 11749 C CA  . VAL D 1 428 ? -7.552  -73.617 63.389  1.00 60.10  ? 428 VAL D CA  1 
ATOM 11750 C C   . VAL D 1 428 ? -6.927  -74.019 64.716  1.00 61.07  ? 428 VAL D C   1 
ATOM 11751 O O   . VAL D 1 428 ? -7.361  -73.567 65.783  1.00 57.77  ? 428 VAL D O   1 
ATOM 11752 C CB  . VAL D 1 428 ? -8.536  -74.687 62.886  1.00 52.16  ? 428 VAL D CB  1 
ATOM 11753 C CG1 . VAL D 1 428 ? -9.431  -75.166 64.021  1.00 54.83  ? 428 VAL D CG1 1 
ATOM 11754 C CG2 . VAL D 1 428 ? -9.372  -74.135 61.760  1.00 54.37  ? 428 VAL D CG2 1 
ATOM 11755 N N   . GLU D 1 429 ? -5.911  -74.882 64.681  1.00 54.35  ? 429 GLU D N   1 
ATOM 11756 C CA  . GLU D 1 429 ? -5.296  -75.275 65.943  1.00 63.52  ? 429 GLU D CA  1 
ATOM 11757 C C   . GLU D 1 429 ? -4.575  -74.097 66.596  1.00 61.59  ? 429 GLU D C   1 
ATOM 11758 O O   . GLU D 1 429 ? -4.566  -73.991 67.826  1.00 60.59  ? 429 GLU D O   1 
ATOM 11759 C CB  . GLU D 1 429 ? -4.357  -76.466 65.755  1.00 63.01  ? 429 GLU D CB  1 
ATOM 11760 C CG  . GLU D 1 429 ? -3.096  -76.196 64.971  1.00 63.31  ? 429 GLU D CG  1 
ATOM 11761 C CD  . GLU D 1 429 ? -2.244  -77.437 64.797  1.00 76.41  ? 429 GLU D CD  1 
ATOM 11762 O OE1 . GLU D 1 429 ? -2.336  -78.355 65.641  1.00 92.06  ? 429 GLU D OE1 1 
ATOM 11763 O OE2 . GLU D 1 429 ? -1.484  -77.498 63.809  1.00 75.33  ? 429 GLU D OE2 1 
ATOM 11764 N N   . GLU D 1 430 ? -4.022  -73.171 65.805  1.00 58.85  ? 430 GLU D N   1 
ATOM 11765 C CA  . GLU D 1 430 ? -3.412  -71.994 66.417  1.00 59.14  ? 430 GLU D CA  1 
ATOM 11766 C C   . GLU D 1 430 ? -4.464  -71.036 66.970  1.00 57.62  ? 430 GLU D C   1 
ATOM 11767 O O   . GLU D 1 430 ? -4.236  -70.411 68.012  1.00 53.20  ? 430 GLU D O   1 
ATOM 11768 C CB  . GLU D 1 430 ? -2.492  -71.275 65.426  1.00 65.16  ? 430 GLU D CB  1 
ATOM 11769 C CG  . GLU D 1 430 ? -1.341  -70.528 66.104  1.00 66.61  ? 430 GLU D CG  1 
ATOM 11770 C CD  . GLU D 1 430 ? -0.070  -70.497 65.261  1.00 66.99  ? 430 GLU D CD  1 
ATOM 11771 O OE1 . GLU D 1 430 ? -0.175  -70.570 64.014  1.00 80.98  ? 430 GLU D OE1 1 
ATOM 11772 O OE2 . GLU D 1 430 ? 1.037   -70.399 65.844  1.00 70.55  ? 430 GLU D OE2 1 
ATOM 11773 N N   . LEU D 1 431 ? -5.619  -70.922 66.310  1.00 58.51  ? 431 LEU D N   1 
ATOM 11774 C CA  . LEU D 1 431 ? -6.705  -70.125 66.883  1.00 54.87  ? 431 LEU D CA  1 
ATOM 11775 C C   . LEU D 1 431 ? -7.174  -70.711 68.212  1.00 53.98  ? 431 LEU D C   1 
ATOM 11776 O O   . LEU D 1 431 ? -7.405  -69.978 69.183  1.00 51.49  ? 431 LEU D O   1 
ATOM 11777 C CB  . LEU D 1 431 ? -7.868  -70.031 65.897  1.00 49.50  ? 431 LEU D CB  1 
ATOM 11778 C CG  . LEU D 1 431 ? -7.690  -69.111 64.685  1.00 41.42  ? 431 LEU D CG  1 
ATOM 11779 C CD1 . LEU D 1 431 ? -8.757  -69.375 63.628  1.00 47.60  ? 431 LEU D CD1 1 
ATOM 11780 C CD2 . LEU D 1 431 ? -7.710  -67.648 65.105  1.00 45.89  ? 431 LEU D CD2 1 
ATOM 11781 N N   . VAL D 1 432 ? -7.316  -72.037 68.271  1.00 55.33  ? 432 VAL D N   1 
ATOM 11782 C CA  . VAL D 1 432 ? -7.676  -72.692 69.526  1.00 58.60  ? 432 VAL D CA  1 
ATOM 11783 C C   . VAL D 1 432 ? -6.593  -72.476 70.573  1.00 60.75  ? 432 VAL D C   1 
ATOM 11784 O O   . VAL D 1 432 ? -6.884  -72.340 71.768  1.00 64.23  ? 432 VAL D O   1 
ATOM 11785 C CB  . VAL D 1 432 ? -7.950  -74.190 69.285  1.00 61.15  ? 432 VAL D CB  1 
ATOM 11786 C CG1 . VAL D 1 432 ? -8.244  -74.905 70.597  1.00 50.32  ? 432 VAL D CG1 1 
ATOM 11787 C CG2 . VAL D 1 432 ? -9.107  -74.363 68.320  1.00 54.30  ? 432 VAL D CG2 1 
ATOM 11788 N N   . GLN D 1 433 ? -5.327  -72.441 70.148  1.00 54.14  ? 433 GLN D N   1 
ATOM 11789 C CA  . GLN D 1 433 ? -4.251  -72.103 71.072  1.00 55.20  ? 433 GLN D CA  1 
ATOM 11790 C C   . GLN D 1 433 ? -4.430  -70.695 71.625  1.00 54.79  ? 433 GLN D C   1 
ATOM 11791 O O   . GLN D 1 433 ? -4.207  -70.457 72.816  1.00 54.46  ? 433 GLN D O   1 
ATOM 11792 C CB  . GLN D 1 433 ? -2.896  -72.243 70.377  1.00 58.86  ? 433 GLN D CB  1 
ATOM 11793 C CG  . GLN D 1 433 ? -1.701  -71.951 71.272  1.00 70.32  ? 433 GLN D CG  1 
ATOM 11794 C CD  . GLN D 1 433 ? -0.377  -72.150 70.558  1.00 74.58  ? 433 GLN D CD  1 
ATOM 11795 O OE1 . GLN D 1 433 ? -0.340  -72.515 69.383  1.00 77.05  ? 433 GLN D OE1 1 
ATOM 11796 N NE2 . GLN D 1 433 ? 0.722   -71.914 71.269  1.00 71.99  ? 433 GLN D NE2 1 
ATOM 11797 N N   . ILE D 1 434 ? -4.831  -69.746 70.777  1.00 55.45  ? 434 ILE D N   1 
ATOM 11798 C CA  . ILE D 1 434 ? -5.100  -68.391 71.260  1.00 58.01  ? 434 ILE D CA  1 
ATOM 11799 C C   . ILE D 1 434 ? -6.206  -68.424 72.310  1.00 61.96  ? 434 ILE D C   1 
ATOM 11800 O O   . ILE D 1 434 ? -6.092  -67.820 73.388  1.00 60.78  ? 434 ILE D O   1 
ATOM 11801 C CB  . ILE D 1 434 ? -5.464  -67.452 70.097  1.00 56.25  ? 434 ILE D CB  1 
ATOM 11802 C CG1 . ILE D 1 434 ? -4.355  -67.429 69.045  1.00 54.05  ? 434 ILE D CG1 1 
ATOM 11803 C CG2 . ILE D 1 434 ? -5.731  -66.046 70.614  1.00 40.28  ? 434 ILE D CG2 1 
ATOM 11804 C CD1 . ILE D 1 434 ? -2.975  -67.241 69.624  1.00 71.38  ? 434 ILE D CD1 1 
ATOM 11805 N N   . CYS D 1 435 ? -7.285  -69.152 72.013  1.00 63.77  ? 435 CYS D N   1 
ATOM 11806 C CA  . CYS D 1 435 ? -8.413  -69.209 72.940  1.00 61.54  ? 435 CYS D CA  1 
ATOM 11807 C C   . CYS D 1 435 ? -8.012  -69.824 74.280  1.00 67.04  ? 435 CYS D C   1 
ATOM 11808 O O   . CYS D 1 435 ? -8.428  -69.342 75.337  1.00 67.51  ? 435 CYS D O   1 
ATOM 11809 C CB  . CYS D 1 435 ? -9.574  -69.980 72.311  1.00 48.74  ? 435 CYS D CB  1 
ATOM 11810 S SG  . CYS D 1 435 ? -10.465 -69.050 71.041  1.00 50.75  ? 435 CYS D SG  1 
ATOM 11811 N N   . LYS D 1 436 ? -7.194  -70.881 74.256  1.00 65.20  ? 436 LYS D N   1 
ATOM 11812 C CA  . LYS D 1 436 ? -6.778  -71.496 75.516  1.00 61.58  ? 436 LYS D CA  1 
ATOM 11813 C C   . LYS D 1 436 ? -5.756  -70.636 76.250  1.00 73.44  ? 436 LYS D C   1 
ATOM 11814 O O   . LYS D 1 436 ? -5.672  -70.694 77.482  1.00 73.92  ? 436 LYS D O   1 
ATOM 11815 C CB  . LYS D 1 436 ? -6.218  -72.900 75.276  1.00 64.41  ? 436 LYS D CB  1 
ATOM 11816 C CG  . LYS D 1 436 ? -4.858  -72.919 74.608  1.00 72.41  ? 436 LYS D CG  1 
ATOM 11817 C CD  . LYS D 1 436 ? -4.201  -74.284 74.681  1.00 81.48  ? 436 LYS D CD  1 
ATOM 11818 C CE  . LYS D 1 436 ? -2.875  -74.279 73.921  1.00 69.29  ? 436 LYS D CE  1 
ATOM 11819 N NZ  . LYS D 1 436 ? -1.958  -73.205 74.401  1.00 67.36  ? 436 LYS D NZ  1 
ATOM 11820 N N   . LYS D 1 437 ? -4.975  -69.808 75.575  1.00 73.92  ? 437 LYS D N   1 
ATOM 11821 C CA  . LYS D 1 437 ? -4.047  -68.966 76.367  1.00 67.37  ? 437 LYS D CA  1 
ATOM 11822 C C   . LYS D 1 437 ? -4.886  -67.938 77.113  1.00 70.16  ? 437 LYS D C   1 
ATOM 11823 O O   . LYS D 1 437 ? -4.375  -67.334 78.062  1.00 81.89  ? 437 LYS D O   1 
ATOM 11824 C CB  . LYS D 1 437 ? -3.018  -68.277 75.474  1.00 72.59  ? 437 LYS D CB  1 
ATOM 11825 C CG  . LYS D 1 437 ? -1.838  -67.631 76.188  1.00 77.66  ? 437 LYS D CG  1 
ATOM 11826 C CD  . LYS D 1 437 ? -0.992  -66.762 75.284  1.00 80.43  ? 437 LYS D CD  1 
ATOM 11827 C CE  . LYS D 1 437 ? -1.768  -65.619 74.667  1.00 89.62  ? 437 LYS D CE  1 
ATOM 11828 N NZ  . LYS D 1 437 ? -2.257  -64.665 75.689  1.00 90.04  ? 437 LYS D NZ  1 
ATOM 11829 N N   . LYS D 1 438 ? -6.136  -67.763 76.694  1.00 73.06  ? 438 LYS D N   1 
ATOM 11830 C CA  . LYS D 1 438 ? -7.018  -66.751 77.333  1.00 77.22  ? 438 LYS D CA  1 
ATOM 11831 C C   . LYS D 1 438 ? -7.815  -67.404 78.460  1.00 72.87  ? 438 LYS D C   1 
ATOM 11832 O O   . LYS D 1 438 ? -8.565  -66.696 79.139  1.00 66.35  ? 438 LYS D O   1 
ATOM 11833 C CB  . LYS D 1 438 ? -7.870  -66.031 76.287  1.00 66.78  ? 438 LYS D CB  1 
ATOM 11834 C CG  . LYS D 1 438 ? -7.116  -65.062 75.388  1.00 75.53  ? 438 LYS D CG  1 
ATOM 11835 C CD  . LYS D 1 438 ? -6.855  -63.730 76.051  1.00 72.59  ? 438 LYS D CD  1 
ATOM 11836 C CE  . LYS D 1 438 ? -8.127  -63.041 76.495  1.00 63.16  ? 438 LYS D CE  1 
ATOM 11837 N NZ  . LYS D 1 438 ? -7.861  -61.682 77.019  1.00 57.95  ? 438 LYS D NZ  1 
ATOM 11838 N N   . LYS D 1 439 ? -7.648  -68.707 78.654  1.00 77.31  ? 439 LYS D N   1 
ATOM 11839 C CA  . LYS D 1 439 ? -8.295  -69.371 79.807  1.00 72.73  ? 439 LYS D CA  1 
ATOM 11840 C C   . LYS D 1 439 ? -7.382  -69.139 81.004  1.00 81.88  ? 439 LYS D C   1 
ATOM 11841 O O   . LYS D 1 439 ? -6.732  -70.095 81.442  1.00 71.21  ? 439 LYS D O   1 
ATOM 11842 C CB  . LYS D 1 439 ? -8.457  -70.865 79.535  1.00 77.41  ? 439 LYS D CB  1 
ATOM 11843 C CG  . LYS D 1 439 ? -9.599  -71.232 78.600  1.00 65.76  ? 439 LYS D CG  1 
ATOM 11844 C CD  . LYS D 1 439 ? -10.936 -70.728 79.096  1.00 76.28  ? 439 LYS D CD  1 
ATOM 11845 C CE  . LYS D 1 439 ? -11.304 -71.256 80.466  1.00 88.73  ? 439 LYS D CE  1 
ATOM 11846 N NZ  . LYS D 1 439 ? -12.513 -70.587 80.998  1.00 85.25  ? 439 LYS D NZ  1 
ATOM 11847 N N   . ASP D 1 440 ? -7.312  -67.896 81.477  1.00 87.10  ? 440 ASP D N   1 
ATOM 11848 C CA  . ASP D 1 440 ? -6.492  -67.550 82.661  1.00 77.27  ? 440 ASP D CA  1 
ATOM 11849 C C   . ASP D 1 440 ? -7.464  -67.112 83.755  1.00 90.01  ? 440 ASP D C   1 
ATOM 11850 O O   . ASP D 1 440 ? -8.325  -66.274 83.458  1.00 98.93  ? 440 ASP D O   1 
ATOM 11851 C CB  . ASP D 1 440 ? -5.435  -66.498 82.325  1.00 81.33  ? 440 ASP D CB  1 
ATOM 11852 C CG  . ASP D 1 440 ? -5.855  -65.442 81.313  1.00 94.32  ? 440 ASP D CG  1 
ATOM 11853 O OD1 . ASP D 1 440 ? -7.034  -65.046 81.322  1.00 97.10  ? 440 ASP D OD1 1 
ATOM 11854 O OD2 . ASP D 1 440 ? -4.992  -65.017 80.524  1.00 93.35  ? 440 ASP D OD2 1 
ATOM 11855 N N   . GLU D 1 441 ? -7.348  -67.685 84.954  1.00 96.42  ? 441 GLU D N   1 
ATOM 11856 C CA  . GLU D 1 441 ? -8.311  -67.393 86.042  1.00 94.50  ? 441 GLU D CA  1 
ATOM 11857 C C   . GLU D 1 441 ? -9.730  -67.702 85.569  1.00 94.06  ? 441 GLU D C   1 
ATOM 11858 O O   . GLU D 1 441 ? -10.612 -66.872 85.838  1.00 91.12  ? 441 GLU D O   1 
ATOM 11859 C CB  . GLU D 1 441 ? -8.194  -65.945 86.504  1.00 102.76 ? 441 GLU D CB  1 
ATOM 11860 C CG  . GLU D 1 441 ? -6.764  -65.501 86.768  1.00 107.32 ? 441 GLU D CG  1 
ATOM 11861 C CD  . GLU D 1 441 ? -6.089  -66.109 87.986  1.00 100.80 ? 441 GLU D CD  1 
ATOM 11862 O OE1 . GLU D 1 441 ? -5.738  -67.305 87.936  1.00 99.75  ? 441 GLU D OE1 1 
ATOM 11863 O OE2 . GLU D 1 441 ? -5.907  -65.376 88.978  1.00 87.50  ? 441 GLU D OE2 1 
ATOM 11864 N N   . GLN D 1 442 ? -9.932  -68.821 84.861  1.00 98.19  ? 442 GLN D N   1 
ATOM 11865 C CA  . GLN D 1 442 ? -11.295 -69.269 84.455  1.00 97.68  ? 442 GLN D CA  1 
ATOM 11866 C C   . GLN D 1 442 ? -12.041 -68.162 83.706  1.00 82.01  ? 442 GLN D C   1 
ATOM 11867 O O   . GLN D 1 442 ? -13.013 -68.515 83.011  1.00 70.95  ? 442 GLN D O   1 
ATOM 11868 C CB  . GLN D 1 442 ? -12.087 -69.744 85.674  1.00 88.52  ? 442 GLN D CB  1 
ATOM 11869 C CG  . GLN D 1 442 ? -11.450 -70.920 86.399  1.00 78.80  ? 442 GLN D CG  1 
ATOM 11870 C CD  . GLN D 1 442 ? -10.766 -70.502 87.677  1.00 78.82  ? 442 GLN D CD  1 
ATOM 11871 O OE1 . GLN D 1 442 ? -10.931 -69.383 88.155  1.00 76.45  ? 442 GLN D OE1 1 
ATOM 11872 N NE2 . GLN D 1 442 ? -9.990  -71.408 88.248  1.00 76.65  ? 442 GLN D NE2 1 
# 
