data_9JUL
# 
_entry.id   9JUL 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JUL         pdb_00009jul 10.2210/pdb9jul/pdb 
WWPDB D_1300052056 ?            ?                   
EMDB  EMD-61829    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-05 ? 
2 'EM metadata'     1 0 2025-03-05 ? 
3 'Half map'        1 0 2025-03-05 1 
4 'Half map'        1 0 2025-03-05 2 
5 Image             1 0 2025-03-05 ? 
6 'Primary map'     1 0 2025-03-05 ? 
7 'Structure model' 1 1 2025-03-19 ? 
8 'EM metadata'     2 0 2025-03-19 ? 
9 'Structure model' 1 2 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7 'Structure model' 'Data collection'      
2 7 'Structure model' 'Database references'  
3 7 'Structure model' 'Structure summary'    
4 8 'EM metadata'     'Database references'  
5 8 'EM metadata'     'Experimental summary' 
6 9 'Structure model' 'Data collection'      
7 9 'Structure model' 'Database references'  
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1  7 'Structure model' audit_author    
2  7 'Structure model' citation_author 
3  7 'Structure model' em_admin        
4  7 'Structure model' em_author_list  
5  8 'EM metadata'     citation_author 
6  8 'EM metadata'     em_admin        
7  8 'EM metadata'     em_author_list  
8  9 'Structure model' citation        
9  9 'Structure model' citation_author 
10 9 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  7 'Structure model' '_em_admin.last_update'             
2  8 'EM metadata'     '_em_admin.last_update'             
3  9 'Structure model' '_citation.country'                 
4  9 'Structure model' '_citation.journal_abbrev'          
5  9 'Structure model' '_citation.journal_id_ASTM'         
6  9 'Structure model' '_citation.journal_id_CSD'          
7  9 'Structure model' '_citation.journal_id_ISSN'         
8  9 'Structure model' '_citation.journal_volume'          
9  9 'Structure model' '_citation.page_first'              
10 9 'Structure model' '_citation.page_last'               
11 9 'Structure model' '_citation.pdbx_database_id_DOI'    
12 9 'Structure model' '_citation.pdbx_database_id_PubMed' 
13 9 'Structure model' '_citation.title'                   
14 9 'Structure model' '_citation.year'                    
15 9 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JUL 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Structure of Arabidopsis thaliana ABCB1 with brassinolide bound in the inward-facing conformation' 
_pdbx_database_related.db_id          EMD-61829 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              sunannan@zju.edu.cn 
_pdbx_contact_author.name_first         Nannan 
_pdbx_contact_author.name_last          Su 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8737-0412 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chen, Q.' 1 0009-0007-1829-4341 
'Su, N.'   2 0000-0002-8737-0412 
'Guo, J.'  3 0000-0002-8850-286X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Structure 
_citation.journal_id_ASTM           STRUE6 
_citation.journal_id_CSD            2005 
_citation.journal_id_ISSN           0969-2126 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            33 
_citation.language                  ? 
_citation.page_first                903 
_citation.page_last                 915.e5 
_citation.title                     'Structures and mechanisms of the ABC transporter ABCB1 from Arabidopsis thaliana.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.str.2025.02.008 
_citation.pdbx_database_id_PubMed   40101709 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chen, Q.'    1 ? 
primary 'Zhu, L.'     2 ? 
primary 'Zhang, S.'   3 ? 
primary 'Qiao, S.'    4 ? 
primary 'Ding, Z.J.'  5 ? 
primary 'Zheng, S.J.' 6 ? 
primary 'Guo, J.'     7 ? 
primary 'Su, N.'      8 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'ABC transporter B family member 1' 145318.953 1 ? ? ? ? 
2 non-polymer syn Brassinolide                        480.677    1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'ABC transporter ABCB.1,AtABCB1,Multidrug resistance protein 1,P-glycoprotein 1,AtPgp1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MDYKDDDDKWSHPQFEKGGGGSGGSAWSHPQFEKEFKGLVDMDNDGGAPPPPPTLVVEEPKKAEIRGVAFKELFRFADGL
DYVLMGIGSVGAFVHGCSLPLFLRFFADLVNSFGSNSNNVEKMMEEVLKYALYFLVVGAAIWASSWAEISCWMWSGERQT
TKMRIKYLEAALNQDIQFFDTEVRTSDVVFAINTDAVMVQDAISEKLGNFIHYMATFVSGFIVGFTAVWQLALVTLAVVP
LIAVIGGIHTTTLSKLSNKSQESLSQAGNIVEQTVVQIRVVMAFVGESRASQAYSSALKIAQKLGYKTGLAKGMGLGATY
FVVFCCYALLLWYGGYLVRHHLTNGGLAIATMFAVMIGGLALGQSAPSMAAFAKAKVAAAKIFRIIDHKPTIERNSESGV
ELDSVTGLVELKNVDFSYPSRPDVKILNNFCLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPNSGQVLLDGQDLKTLKL
RWLRQQIGLVSQEPALFATSIKENILLGRPDADQVEIEEAARVANAHSFIIKLPDGFDTQVGERGLQLSGGQKQRIAIAR
AMLKNPAILLLDEATSALDSESEKLVQEALDRFMIGRTTLIIAHRLSTIRKADLVAVLQQGSVSEIGTHDELFSKGENGV
YAKLIKMQEAAHETAMSNARKSSARPSSARNSVSSPIMTRNSSYGRSPYSRRLSDFSTSDFSLSIDASSYPNYRNEKLAF
KDQANSFWRLAKMNSPEWKYALLGSVGSVICGSLSAFFAYVLSAVLSVYYNPDHEYMIKQIDKYCYLLIGLSSAALVFNT
LQHSFWDIVGENLTKRVREKMLSAVLKNEMAWFDQEENESARIAARLALDANNVRSAIGDRISVIVQNTALMLVACTAGF
VLQWRLALVLVAVFPVVVAATVLQKMFMTGFSGDLEAAHAKGTQLAGEAIANVRTVAAFNSEAKIVRLYTANLEPPLKRC
FWKGQIAGSGYGVAQFCLYASYALGLWYASWLVKHGISDFSKTIRVFMVLMVSANGAAETLTLAPDFIKGGQAMRSVFEL
LDRKTEIEPDDPDTTPVPDRLRGEVELKHIDFSYPSRPDIQIFRDLSLRARAGKTLALVGPSGCGKSSVISLIQRFYEPS
SGRVMIDGKDIRKYNLKAIRKHIAIVPQEPCLFGTTIYENIAYGHECATEAEIIQAATLASAHKFISALPEGYKTYVGER
GVQLSGGQKQRIAIARALVRKAEIMLLDEATSALDAESERSVQEALDQACSGRTSIVVAHRLSTIRNAHVIAVIDDGKVA
EQGSHSHLLKNHPDGIYARMIQLQRFTHTQVIGMTSGSSSRVKEDDA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MDYKDDDDKWSHPQFEKGGGGSGGSAWSHPQFEKEFKGLVDMDNDGGAPPPPPTLVVEEPKKAEIRGVAFKELFRFADGL
DYVLMGIGSVGAFVHGCSLPLFLRFFADLVNSFGSNSNNVEKMMEEVLKYALYFLVVGAAIWASSWAEISCWMWSGERQT
TKMRIKYLEAALNQDIQFFDTEVRTSDVVFAINTDAVMVQDAISEKLGNFIHYMATFVSGFIVGFTAVWQLALVTLAVVP
LIAVIGGIHTTTLSKLSNKSQESLSQAGNIVEQTVVQIRVVMAFVGESRASQAYSSALKIAQKLGYKTGLAKGMGLGATY
FVVFCCYALLLWYGGYLVRHHLTNGGLAIATMFAVMIGGLALGQSAPSMAAFAKAKVAAAKIFRIIDHKPTIERNSESGV
ELDSVTGLVELKNVDFSYPSRPDVKILNNFCLSVPAGKTIALVGSSGSGKSTVVSLIERFYDPNSGQVLLDGQDLKTLKL
RWLRQQIGLVSQEPALFATSIKENILLGRPDADQVEIEEAARVANAHSFIIKLPDGFDTQVGERGLQLSGGQKQRIAIAR
AMLKNPAILLLDEATSALDSESEKLVQEALDRFMIGRTTLIIAHRLSTIRKADLVAVLQQGSVSEIGTHDELFSKGENGV
YAKLIKMQEAAHETAMSNARKSSARPSSARNSVSSPIMTRNSSYGRSPYSRRLSDFSTSDFSLSIDASSYPNYRNEKLAF
KDQANSFWRLAKMNSPEWKYALLGSVGSVICGSLSAFFAYVLSAVLSVYYNPDHEYMIKQIDKYCYLLIGLSSAALVFNT
LQHSFWDIVGENLTKRVREKMLSAVLKNEMAWFDQEENESARIAARLALDANNVRSAIGDRISVIVQNTALMLVACTAGF
VLQWRLALVLVAVFPVVVAATVLQKMFMTGFSGDLEAAHAKGTQLAGEAIANVRTVAAFNSEAKIVRLYTANLEPPLKRC
FWKGQIAGSGYGVAQFCLYASYALGLWYASWLVKHGISDFSKTIRVFMVLMVSANGAAETLTLAPDFIKGGQAMRSVFEL
LDRKTEIEPDDPDTTPVPDRLRGEVELKHIDFSYPSRPDIQIFRDLSLRARAGKTLALVGPSGCGKSSVISLIQRFYEPS
SGRVMIDGKDIRKYNLKAIRKHIAIVPQEPCLFGTTIYENIAYGHECATEAEIIQAATLASAHKFISALPEGYKTYVGER
GVQLSGGQKQRIAIARALVRKAEIMLLDEATSALDAESERSVQEALDQACSGRTSIVVAHRLSTIRNAHVIAVIDDGKVA
EQGSHSHLLKNHPDGIYARMIQLQRFTHTQVIGMTSGSSSRVKEDDA
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        Brassinolide 
_pdbx_entity_nonpoly.comp_id     BLD 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    ASP n 
1 3    TYR n 
1 4    LYS n 
1 5    ASP n 
1 6    ASP n 
1 7    ASP n 
1 8    ASP n 
1 9    LYS n 
1 10   TRP n 
1 11   SER n 
1 12   HIS n 
1 13   PRO n 
1 14   GLN n 
1 15   PHE n 
1 16   GLU n 
1 17   LYS n 
1 18   GLY n 
1 19   GLY n 
1 20   GLY n 
1 21   GLY n 
1 22   SER n 
1 23   GLY n 
1 24   GLY n 
1 25   SER n 
1 26   ALA n 
1 27   TRP n 
1 28   SER n 
1 29   HIS n 
1 30   PRO n 
1 31   GLN n 
1 32   PHE n 
1 33   GLU n 
1 34   LYS n 
1 35   GLU n 
1 36   PHE n 
1 37   LYS n 
1 38   GLY n 
1 39   LEU n 
1 40   VAL n 
1 41   ASP n 
1 42   MET n 
1 43   ASP n 
1 44   ASN n 
1 45   ASP n 
1 46   GLY n 
1 47   GLY n 
1 48   ALA n 
1 49   PRO n 
1 50   PRO n 
1 51   PRO n 
1 52   PRO n 
1 53   PRO n 
1 54   THR n 
1 55   LEU n 
1 56   VAL n 
1 57   VAL n 
1 58   GLU n 
1 59   GLU n 
1 60   PRO n 
1 61   LYS n 
1 62   LYS n 
1 63   ALA n 
1 64   GLU n 
1 65   ILE n 
1 66   ARG n 
1 67   GLY n 
1 68   VAL n 
1 69   ALA n 
1 70   PHE n 
1 71   LYS n 
1 72   GLU n 
1 73   LEU n 
1 74   PHE n 
1 75   ARG n 
1 76   PHE n 
1 77   ALA n 
1 78   ASP n 
1 79   GLY n 
1 80   LEU n 
1 81   ASP n 
1 82   TYR n 
1 83   VAL n 
1 84   LEU n 
1 85   MET n 
1 86   GLY n 
1 87   ILE n 
1 88   GLY n 
1 89   SER n 
1 90   VAL n 
1 91   GLY n 
1 92   ALA n 
1 93   PHE n 
1 94   VAL n 
1 95   HIS n 
1 96   GLY n 
1 97   CYS n 
1 98   SER n 
1 99   LEU n 
1 100  PRO n 
1 101  LEU n 
1 102  PHE n 
1 103  LEU n 
1 104  ARG n 
1 105  PHE n 
1 106  PHE n 
1 107  ALA n 
1 108  ASP n 
1 109  LEU n 
1 110  VAL n 
1 111  ASN n 
1 112  SER n 
1 113  PHE n 
1 114  GLY n 
1 115  SER n 
1 116  ASN n 
1 117  SER n 
1 118  ASN n 
1 119  ASN n 
1 120  VAL n 
1 121  GLU n 
1 122  LYS n 
1 123  MET n 
1 124  MET n 
1 125  GLU n 
1 126  GLU n 
1 127  VAL n 
1 128  LEU n 
1 129  LYS n 
1 130  TYR n 
1 131  ALA n 
1 132  LEU n 
1 133  TYR n 
1 134  PHE n 
1 135  LEU n 
1 136  VAL n 
1 137  VAL n 
1 138  GLY n 
1 139  ALA n 
1 140  ALA n 
1 141  ILE n 
1 142  TRP n 
1 143  ALA n 
1 144  SER n 
1 145  SER n 
1 146  TRP n 
1 147  ALA n 
1 148  GLU n 
1 149  ILE n 
1 150  SER n 
1 151  CYS n 
1 152  TRP n 
1 153  MET n 
1 154  TRP n 
1 155  SER n 
1 156  GLY n 
1 157  GLU n 
1 158  ARG n 
1 159  GLN n 
1 160  THR n 
1 161  THR n 
1 162  LYS n 
1 163  MET n 
1 164  ARG n 
1 165  ILE n 
1 166  LYS n 
1 167  TYR n 
1 168  LEU n 
1 169  GLU n 
1 170  ALA n 
1 171  ALA n 
1 172  LEU n 
1 173  ASN n 
1 174  GLN n 
1 175  ASP n 
1 176  ILE n 
1 177  GLN n 
1 178  PHE n 
1 179  PHE n 
1 180  ASP n 
1 181  THR n 
1 182  GLU n 
1 183  VAL n 
1 184  ARG n 
1 185  THR n 
1 186  SER n 
1 187  ASP n 
1 188  VAL n 
1 189  VAL n 
1 190  PHE n 
1 191  ALA n 
1 192  ILE n 
1 193  ASN n 
1 194  THR n 
1 195  ASP n 
1 196  ALA n 
1 197  VAL n 
1 198  MET n 
1 199  VAL n 
1 200  GLN n 
1 201  ASP n 
1 202  ALA n 
1 203  ILE n 
1 204  SER n 
1 205  GLU n 
1 206  LYS n 
1 207  LEU n 
1 208  GLY n 
1 209  ASN n 
1 210  PHE n 
1 211  ILE n 
1 212  HIS n 
1 213  TYR n 
1 214  MET n 
1 215  ALA n 
1 216  THR n 
1 217  PHE n 
1 218  VAL n 
1 219  SER n 
1 220  GLY n 
1 221  PHE n 
1 222  ILE n 
1 223  VAL n 
1 224  GLY n 
1 225  PHE n 
1 226  THR n 
1 227  ALA n 
1 228  VAL n 
1 229  TRP n 
1 230  GLN n 
1 231  LEU n 
1 232  ALA n 
1 233  LEU n 
1 234  VAL n 
1 235  THR n 
1 236  LEU n 
1 237  ALA n 
1 238  VAL n 
1 239  VAL n 
1 240  PRO n 
1 241  LEU n 
1 242  ILE n 
1 243  ALA n 
1 244  VAL n 
1 245  ILE n 
1 246  GLY n 
1 247  GLY n 
1 248  ILE n 
1 249  HIS n 
1 250  THR n 
1 251  THR n 
1 252  THR n 
1 253  LEU n 
1 254  SER n 
1 255  LYS n 
1 256  LEU n 
1 257  SER n 
1 258  ASN n 
1 259  LYS n 
1 260  SER n 
1 261  GLN n 
1 262  GLU n 
1 263  SER n 
1 264  LEU n 
1 265  SER n 
1 266  GLN n 
1 267  ALA n 
1 268  GLY n 
1 269  ASN n 
1 270  ILE n 
1 271  VAL n 
1 272  GLU n 
1 273  GLN n 
1 274  THR n 
1 275  VAL n 
1 276  VAL n 
1 277  GLN n 
1 278  ILE n 
1 279  ARG n 
1 280  VAL n 
1 281  VAL n 
1 282  MET n 
1 283  ALA n 
1 284  PHE n 
1 285  VAL n 
1 286  GLY n 
1 287  GLU n 
1 288  SER n 
1 289  ARG n 
1 290  ALA n 
1 291  SER n 
1 292  GLN n 
1 293  ALA n 
1 294  TYR n 
1 295  SER n 
1 296  SER n 
1 297  ALA n 
1 298  LEU n 
1 299  LYS n 
1 300  ILE n 
1 301  ALA n 
1 302  GLN n 
1 303  LYS n 
1 304  LEU n 
1 305  GLY n 
1 306  TYR n 
1 307  LYS n 
1 308  THR n 
1 309  GLY n 
1 310  LEU n 
1 311  ALA n 
1 312  LYS n 
1 313  GLY n 
1 314  MET n 
1 315  GLY n 
1 316  LEU n 
1 317  GLY n 
1 318  ALA n 
1 319  THR n 
1 320  TYR n 
1 321  PHE n 
1 322  VAL n 
1 323  VAL n 
1 324  PHE n 
1 325  CYS n 
1 326  CYS n 
1 327  TYR n 
1 328  ALA n 
1 329  LEU n 
1 330  LEU n 
1 331  LEU n 
1 332  TRP n 
1 333  TYR n 
1 334  GLY n 
1 335  GLY n 
1 336  TYR n 
1 337  LEU n 
1 338  VAL n 
1 339  ARG n 
1 340  HIS n 
1 341  HIS n 
1 342  LEU n 
1 343  THR n 
1 344  ASN n 
1 345  GLY n 
1 346  GLY n 
1 347  LEU n 
1 348  ALA n 
1 349  ILE n 
1 350  ALA n 
1 351  THR n 
1 352  MET n 
1 353  PHE n 
1 354  ALA n 
1 355  VAL n 
1 356  MET n 
1 357  ILE n 
1 358  GLY n 
1 359  GLY n 
1 360  LEU n 
1 361  ALA n 
1 362  LEU n 
1 363  GLY n 
1 364  GLN n 
1 365  SER n 
1 366  ALA n 
1 367  PRO n 
1 368  SER n 
1 369  MET n 
1 370  ALA n 
1 371  ALA n 
1 372  PHE n 
1 373  ALA n 
1 374  LYS n 
1 375  ALA n 
1 376  LYS n 
1 377  VAL n 
1 378  ALA n 
1 379  ALA n 
1 380  ALA n 
1 381  LYS n 
1 382  ILE n 
1 383  PHE n 
1 384  ARG n 
1 385  ILE n 
1 386  ILE n 
1 387  ASP n 
1 388  HIS n 
1 389  LYS n 
1 390  PRO n 
1 391  THR n 
1 392  ILE n 
1 393  GLU n 
1 394  ARG n 
1 395  ASN n 
1 396  SER n 
1 397  GLU n 
1 398  SER n 
1 399  GLY n 
1 400  VAL n 
1 401  GLU n 
1 402  LEU n 
1 403  ASP n 
1 404  SER n 
1 405  VAL n 
1 406  THR n 
1 407  GLY n 
1 408  LEU n 
1 409  VAL n 
1 410  GLU n 
1 411  LEU n 
1 412  LYS n 
1 413  ASN n 
1 414  VAL n 
1 415  ASP n 
1 416  PHE n 
1 417  SER n 
1 418  TYR n 
1 419  PRO n 
1 420  SER n 
1 421  ARG n 
1 422  PRO n 
1 423  ASP n 
1 424  VAL n 
1 425  LYS n 
1 426  ILE n 
1 427  LEU n 
1 428  ASN n 
1 429  ASN n 
1 430  PHE n 
1 431  CYS n 
1 432  LEU n 
1 433  SER n 
1 434  VAL n 
1 435  PRO n 
1 436  ALA n 
1 437  GLY n 
1 438  LYS n 
1 439  THR n 
1 440  ILE n 
1 441  ALA n 
1 442  LEU n 
1 443  VAL n 
1 444  GLY n 
1 445  SER n 
1 446  SER n 
1 447  GLY n 
1 448  SER n 
1 449  GLY n 
1 450  LYS n 
1 451  SER n 
1 452  THR n 
1 453  VAL n 
1 454  VAL n 
1 455  SER n 
1 456  LEU n 
1 457  ILE n 
1 458  GLU n 
1 459  ARG n 
1 460  PHE n 
1 461  TYR n 
1 462  ASP n 
1 463  PRO n 
1 464  ASN n 
1 465  SER n 
1 466  GLY n 
1 467  GLN n 
1 468  VAL n 
1 469  LEU n 
1 470  LEU n 
1 471  ASP n 
1 472  GLY n 
1 473  GLN n 
1 474  ASP n 
1 475  LEU n 
1 476  LYS n 
1 477  THR n 
1 478  LEU n 
1 479  LYS n 
1 480  LEU n 
1 481  ARG n 
1 482  TRP n 
1 483  LEU n 
1 484  ARG n 
1 485  GLN n 
1 486  GLN n 
1 487  ILE n 
1 488  GLY n 
1 489  LEU n 
1 490  VAL n 
1 491  SER n 
1 492  GLN n 
1 493  GLU n 
1 494  PRO n 
1 495  ALA n 
1 496  LEU n 
1 497  PHE n 
1 498  ALA n 
1 499  THR n 
1 500  SER n 
1 501  ILE n 
1 502  LYS n 
1 503  GLU n 
1 504  ASN n 
1 505  ILE n 
1 506  LEU n 
1 507  LEU n 
1 508  GLY n 
1 509  ARG n 
1 510  PRO n 
1 511  ASP n 
1 512  ALA n 
1 513  ASP n 
1 514  GLN n 
1 515  VAL n 
1 516  GLU n 
1 517  ILE n 
1 518  GLU n 
1 519  GLU n 
1 520  ALA n 
1 521  ALA n 
1 522  ARG n 
1 523  VAL n 
1 524  ALA n 
1 525  ASN n 
1 526  ALA n 
1 527  HIS n 
1 528  SER n 
1 529  PHE n 
1 530  ILE n 
1 531  ILE n 
1 532  LYS n 
1 533  LEU n 
1 534  PRO n 
1 535  ASP n 
1 536  GLY n 
1 537  PHE n 
1 538  ASP n 
1 539  THR n 
1 540  GLN n 
1 541  VAL n 
1 542  GLY n 
1 543  GLU n 
1 544  ARG n 
1 545  GLY n 
1 546  LEU n 
1 547  GLN n 
1 548  LEU n 
1 549  SER n 
1 550  GLY n 
1 551  GLY n 
1 552  GLN n 
1 553  LYS n 
1 554  GLN n 
1 555  ARG n 
1 556  ILE n 
1 557  ALA n 
1 558  ILE n 
1 559  ALA n 
1 560  ARG n 
1 561  ALA n 
1 562  MET n 
1 563  LEU n 
1 564  LYS n 
1 565  ASN n 
1 566  PRO n 
1 567  ALA n 
1 568  ILE n 
1 569  LEU n 
1 570  LEU n 
1 571  LEU n 
1 572  ASP n 
1 573  GLU n 
1 574  ALA n 
1 575  THR n 
1 576  SER n 
1 577  ALA n 
1 578  LEU n 
1 579  ASP n 
1 580  SER n 
1 581  GLU n 
1 582  SER n 
1 583  GLU n 
1 584  LYS n 
1 585  LEU n 
1 586  VAL n 
1 587  GLN n 
1 588  GLU n 
1 589  ALA n 
1 590  LEU n 
1 591  ASP n 
1 592  ARG n 
1 593  PHE n 
1 594  MET n 
1 595  ILE n 
1 596  GLY n 
1 597  ARG n 
1 598  THR n 
1 599  THR n 
1 600  LEU n 
1 601  ILE n 
1 602  ILE n 
1 603  ALA n 
1 604  HIS n 
1 605  ARG n 
1 606  LEU n 
1 607  SER n 
1 608  THR n 
1 609  ILE n 
1 610  ARG n 
1 611  LYS n 
1 612  ALA n 
1 613  ASP n 
1 614  LEU n 
1 615  VAL n 
1 616  ALA n 
1 617  VAL n 
1 618  LEU n 
1 619  GLN n 
1 620  GLN n 
1 621  GLY n 
1 622  SER n 
1 623  VAL n 
1 624  SER n 
1 625  GLU n 
1 626  ILE n 
1 627  GLY n 
1 628  THR n 
1 629  HIS n 
1 630  ASP n 
1 631  GLU n 
1 632  LEU n 
1 633  PHE n 
1 634  SER n 
1 635  LYS n 
1 636  GLY n 
1 637  GLU n 
1 638  ASN n 
1 639  GLY n 
1 640  VAL n 
1 641  TYR n 
1 642  ALA n 
1 643  LYS n 
1 644  LEU n 
1 645  ILE n 
1 646  LYS n 
1 647  MET n 
1 648  GLN n 
1 649  GLU n 
1 650  ALA n 
1 651  ALA n 
1 652  HIS n 
1 653  GLU n 
1 654  THR n 
1 655  ALA n 
1 656  MET n 
1 657  SER n 
1 658  ASN n 
1 659  ALA n 
1 660  ARG n 
1 661  LYS n 
1 662  SER n 
1 663  SER n 
1 664  ALA n 
1 665  ARG n 
1 666  PRO n 
1 667  SER n 
1 668  SER n 
1 669  ALA n 
1 670  ARG n 
1 671  ASN n 
1 672  SER n 
1 673  VAL n 
1 674  SER n 
1 675  SER n 
1 676  PRO n 
1 677  ILE n 
1 678  MET n 
1 679  THR n 
1 680  ARG n 
1 681  ASN n 
1 682  SER n 
1 683  SER n 
1 684  TYR n 
1 685  GLY n 
1 686  ARG n 
1 687  SER n 
1 688  PRO n 
1 689  TYR n 
1 690  SER n 
1 691  ARG n 
1 692  ARG n 
1 693  LEU n 
1 694  SER n 
1 695  ASP n 
1 696  PHE n 
1 697  SER n 
1 698  THR n 
1 699  SER n 
1 700  ASP n 
1 701  PHE n 
1 702  SER n 
1 703  LEU n 
1 704  SER n 
1 705  ILE n 
1 706  ASP n 
1 707  ALA n 
1 708  SER n 
1 709  SER n 
1 710  TYR n 
1 711  PRO n 
1 712  ASN n 
1 713  TYR n 
1 714  ARG n 
1 715  ASN n 
1 716  GLU n 
1 717  LYS n 
1 718  LEU n 
1 719  ALA n 
1 720  PHE n 
1 721  LYS n 
1 722  ASP n 
1 723  GLN n 
1 724  ALA n 
1 725  ASN n 
1 726  SER n 
1 727  PHE n 
1 728  TRP n 
1 729  ARG n 
1 730  LEU n 
1 731  ALA n 
1 732  LYS n 
1 733  MET n 
1 734  ASN n 
1 735  SER n 
1 736  PRO n 
1 737  GLU n 
1 738  TRP n 
1 739  LYS n 
1 740  TYR n 
1 741  ALA n 
1 742  LEU n 
1 743  LEU n 
1 744  GLY n 
1 745  SER n 
1 746  VAL n 
1 747  GLY n 
1 748  SER n 
1 749  VAL n 
1 750  ILE n 
1 751  CYS n 
1 752  GLY n 
1 753  SER n 
1 754  LEU n 
1 755  SER n 
1 756  ALA n 
1 757  PHE n 
1 758  PHE n 
1 759  ALA n 
1 760  TYR n 
1 761  VAL n 
1 762  LEU n 
1 763  SER n 
1 764  ALA n 
1 765  VAL n 
1 766  LEU n 
1 767  SER n 
1 768  VAL n 
1 769  TYR n 
1 770  TYR n 
1 771  ASN n 
1 772  PRO n 
1 773  ASP n 
1 774  HIS n 
1 775  GLU n 
1 776  TYR n 
1 777  MET n 
1 778  ILE n 
1 779  LYS n 
1 780  GLN n 
1 781  ILE n 
1 782  ASP n 
1 783  LYS n 
1 784  TYR n 
1 785  CYS n 
1 786  TYR n 
1 787  LEU n 
1 788  LEU n 
1 789  ILE n 
1 790  GLY n 
1 791  LEU n 
1 792  SER n 
1 793  SER n 
1 794  ALA n 
1 795  ALA n 
1 796  LEU n 
1 797  VAL n 
1 798  PHE n 
1 799  ASN n 
1 800  THR n 
1 801  LEU n 
1 802  GLN n 
1 803  HIS n 
1 804  SER n 
1 805  PHE n 
1 806  TRP n 
1 807  ASP n 
1 808  ILE n 
1 809  VAL n 
1 810  GLY n 
1 811  GLU n 
1 812  ASN n 
1 813  LEU n 
1 814  THR n 
1 815  LYS n 
1 816  ARG n 
1 817  VAL n 
1 818  ARG n 
1 819  GLU n 
1 820  LYS n 
1 821  MET n 
1 822  LEU n 
1 823  SER n 
1 824  ALA n 
1 825  VAL n 
1 826  LEU n 
1 827  LYS n 
1 828  ASN n 
1 829  GLU n 
1 830  MET n 
1 831  ALA n 
1 832  TRP n 
1 833  PHE n 
1 834  ASP n 
1 835  GLN n 
1 836  GLU n 
1 837  GLU n 
1 838  ASN n 
1 839  GLU n 
1 840  SER n 
1 841  ALA n 
1 842  ARG n 
1 843  ILE n 
1 844  ALA n 
1 845  ALA n 
1 846  ARG n 
1 847  LEU n 
1 848  ALA n 
1 849  LEU n 
1 850  ASP n 
1 851  ALA n 
1 852  ASN n 
1 853  ASN n 
1 854  VAL n 
1 855  ARG n 
1 856  SER n 
1 857  ALA n 
1 858  ILE n 
1 859  GLY n 
1 860  ASP n 
1 861  ARG n 
1 862  ILE n 
1 863  SER n 
1 864  VAL n 
1 865  ILE n 
1 866  VAL n 
1 867  GLN n 
1 868  ASN n 
1 869  THR n 
1 870  ALA n 
1 871  LEU n 
1 872  MET n 
1 873  LEU n 
1 874  VAL n 
1 875  ALA n 
1 876  CYS n 
1 877  THR n 
1 878  ALA n 
1 879  GLY n 
1 880  PHE n 
1 881  VAL n 
1 882  LEU n 
1 883  GLN n 
1 884  TRP n 
1 885  ARG n 
1 886  LEU n 
1 887  ALA n 
1 888  LEU n 
1 889  VAL n 
1 890  LEU n 
1 891  VAL n 
1 892  ALA n 
1 893  VAL n 
1 894  PHE n 
1 895  PRO n 
1 896  VAL n 
1 897  VAL n 
1 898  VAL n 
1 899  ALA n 
1 900  ALA n 
1 901  THR n 
1 902  VAL n 
1 903  LEU n 
1 904  GLN n 
1 905  LYS n 
1 906  MET n 
1 907  PHE n 
1 908  MET n 
1 909  THR n 
1 910  GLY n 
1 911  PHE n 
1 912  SER n 
1 913  GLY n 
1 914  ASP n 
1 915  LEU n 
1 916  GLU n 
1 917  ALA n 
1 918  ALA n 
1 919  HIS n 
1 920  ALA n 
1 921  LYS n 
1 922  GLY n 
1 923  THR n 
1 924  GLN n 
1 925  LEU n 
1 926  ALA n 
1 927  GLY n 
1 928  GLU n 
1 929  ALA n 
1 930  ILE n 
1 931  ALA n 
1 932  ASN n 
1 933  VAL n 
1 934  ARG n 
1 935  THR n 
1 936  VAL n 
1 937  ALA n 
1 938  ALA n 
1 939  PHE n 
1 940  ASN n 
1 941  SER n 
1 942  GLU n 
1 943  ALA n 
1 944  LYS n 
1 945  ILE n 
1 946  VAL n 
1 947  ARG n 
1 948  LEU n 
1 949  TYR n 
1 950  THR n 
1 951  ALA n 
1 952  ASN n 
1 953  LEU n 
1 954  GLU n 
1 955  PRO n 
1 956  PRO n 
1 957  LEU n 
1 958  LYS n 
1 959  ARG n 
1 960  CYS n 
1 961  PHE n 
1 962  TRP n 
1 963  LYS n 
1 964  GLY n 
1 965  GLN n 
1 966  ILE n 
1 967  ALA n 
1 968  GLY n 
1 969  SER n 
1 970  GLY n 
1 971  TYR n 
1 972  GLY n 
1 973  VAL n 
1 974  ALA n 
1 975  GLN n 
1 976  PHE n 
1 977  CYS n 
1 978  LEU n 
1 979  TYR n 
1 980  ALA n 
1 981  SER n 
1 982  TYR n 
1 983  ALA n 
1 984  LEU n 
1 985  GLY n 
1 986  LEU n 
1 987  TRP n 
1 988  TYR n 
1 989  ALA n 
1 990  SER n 
1 991  TRP n 
1 992  LEU n 
1 993  VAL n 
1 994  LYS n 
1 995  HIS n 
1 996  GLY n 
1 997  ILE n 
1 998  SER n 
1 999  ASP n 
1 1000 PHE n 
1 1001 SER n 
1 1002 LYS n 
1 1003 THR n 
1 1004 ILE n 
1 1005 ARG n 
1 1006 VAL n 
1 1007 PHE n 
1 1008 MET n 
1 1009 VAL n 
1 1010 LEU n 
1 1011 MET n 
1 1012 VAL n 
1 1013 SER n 
1 1014 ALA n 
1 1015 ASN n 
1 1016 GLY n 
1 1017 ALA n 
1 1018 ALA n 
1 1019 GLU n 
1 1020 THR n 
1 1021 LEU n 
1 1022 THR n 
1 1023 LEU n 
1 1024 ALA n 
1 1025 PRO n 
1 1026 ASP n 
1 1027 PHE n 
1 1028 ILE n 
1 1029 LYS n 
1 1030 GLY n 
1 1031 GLY n 
1 1032 GLN n 
1 1033 ALA n 
1 1034 MET n 
1 1035 ARG n 
1 1036 SER n 
1 1037 VAL n 
1 1038 PHE n 
1 1039 GLU n 
1 1040 LEU n 
1 1041 LEU n 
1 1042 ASP n 
1 1043 ARG n 
1 1044 LYS n 
1 1045 THR n 
1 1046 GLU n 
1 1047 ILE n 
1 1048 GLU n 
1 1049 PRO n 
1 1050 ASP n 
1 1051 ASP n 
1 1052 PRO n 
1 1053 ASP n 
1 1054 THR n 
1 1055 THR n 
1 1056 PRO n 
1 1057 VAL n 
1 1058 PRO n 
1 1059 ASP n 
1 1060 ARG n 
1 1061 LEU n 
1 1062 ARG n 
1 1063 GLY n 
1 1064 GLU n 
1 1065 VAL n 
1 1066 GLU n 
1 1067 LEU n 
1 1068 LYS n 
1 1069 HIS n 
1 1070 ILE n 
1 1071 ASP n 
1 1072 PHE n 
1 1073 SER n 
1 1074 TYR n 
1 1075 PRO n 
1 1076 SER n 
1 1077 ARG n 
1 1078 PRO n 
1 1079 ASP n 
1 1080 ILE n 
1 1081 GLN n 
1 1082 ILE n 
1 1083 PHE n 
1 1084 ARG n 
1 1085 ASP n 
1 1086 LEU n 
1 1087 SER n 
1 1088 LEU n 
1 1089 ARG n 
1 1090 ALA n 
1 1091 ARG n 
1 1092 ALA n 
1 1093 GLY n 
1 1094 LYS n 
1 1095 THR n 
1 1096 LEU n 
1 1097 ALA n 
1 1098 LEU n 
1 1099 VAL n 
1 1100 GLY n 
1 1101 PRO n 
1 1102 SER n 
1 1103 GLY n 
1 1104 CYS n 
1 1105 GLY n 
1 1106 LYS n 
1 1107 SER n 
1 1108 SER n 
1 1109 VAL n 
1 1110 ILE n 
1 1111 SER n 
1 1112 LEU n 
1 1113 ILE n 
1 1114 GLN n 
1 1115 ARG n 
1 1116 PHE n 
1 1117 TYR n 
1 1118 GLU n 
1 1119 PRO n 
1 1120 SER n 
1 1121 SER n 
1 1122 GLY n 
1 1123 ARG n 
1 1124 VAL n 
1 1125 MET n 
1 1126 ILE n 
1 1127 ASP n 
1 1128 GLY n 
1 1129 LYS n 
1 1130 ASP n 
1 1131 ILE n 
1 1132 ARG n 
1 1133 LYS n 
1 1134 TYR n 
1 1135 ASN n 
1 1136 LEU n 
1 1137 LYS n 
1 1138 ALA n 
1 1139 ILE n 
1 1140 ARG n 
1 1141 LYS n 
1 1142 HIS n 
1 1143 ILE n 
1 1144 ALA n 
1 1145 ILE n 
1 1146 VAL n 
1 1147 PRO n 
1 1148 GLN n 
1 1149 GLU n 
1 1150 PRO n 
1 1151 CYS n 
1 1152 LEU n 
1 1153 PHE n 
1 1154 GLY n 
1 1155 THR n 
1 1156 THR n 
1 1157 ILE n 
1 1158 TYR n 
1 1159 GLU n 
1 1160 ASN n 
1 1161 ILE n 
1 1162 ALA n 
1 1163 TYR n 
1 1164 GLY n 
1 1165 HIS n 
1 1166 GLU n 
1 1167 CYS n 
1 1168 ALA n 
1 1169 THR n 
1 1170 GLU n 
1 1171 ALA n 
1 1172 GLU n 
1 1173 ILE n 
1 1174 ILE n 
1 1175 GLN n 
1 1176 ALA n 
1 1177 ALA n 
1 1178 THR n 
1 1179 LEU n 
1 1180 ALA n 
1 1181 SER n 
1 1182 ALA n 
1 1183 HIS n 
1 1184 LYS n 
1 1185 PHE n 
1 1186 ILE n 
1 1187 SER n 
1 1188 ALA n 
1 1189 LEU n 
1 1190 PRO n 
1 1191 GLU n 
1 1192 GLY n 
1 1193 TYR n 
1 1194 LYS n 
1 1195 THR n 
1 1196 TYR n 
1 1197 VAL n 
1 1198 GLY n 
1 1199 GLU n 
1 1200 ARG n 
1 1201 GLY n 
1 1202 VAL n 
1 1203 GLN n 
1 1204 LEU n 
1 1205 SER n 
1 1206 GLY n 
1 1207 GLY n 
1 1208 GLN n 
1 1209 LYS n 
1 1210 GLN n 
1 1211 ARG n 
1 1212 ILE n 
1 1213 ALA n 
1 1214 ILE n 
1 1215 ALA n 
1 1216 ARG n 
1 1217 ALA n 
1 1218 LEU n 
1 1219 VAL n 
1 1220 ARG n 
1 1221 LYS n 
1 1222 ALA n 
1 1223 GLU n 
1 1224 ILE n 
1 1225 MET n 
1 1226 LEU n 
1 1227 LEU n 
1 1228 ASP n 
1 1229 GLU n 
1 1230 ALA n 
1 1231 THR n 
1 1232 SER n 
1 1233 ALA n 
1 1234 LEU n 
1 1235 ASP n 
1 1236 ALA n 
1 1237 GLU n 
1 1238 SER n 
1 1239 GLU n 
1 1240 ARG n 
1 1241 SER n 
1 1242 VAL n 
1 1243 GLN n 
1 1244 GLU n 
1 1245 ALA n 
1 1246 LEU n 
1 1247 ASP n 
1 1248 GLN n 
1 1249 ALA n 
1 1250 CYS n 
1 1251 SER n 
1 1252 GLY n 
1 1253 ARG n 
1 1254 THR n 
1 1255 SER n 
1 1256 ILE n 
1 1257 VAL n 
1 1258 VAL n 
1 1259 ALA n 
1 1260 HIS n 
1 1261 ARG n 
1 1262 LEU n 
1 1263 SER n 
1 1264 THR n 
1 1265 ILE n 
1 1266 ARG n 
1 1267 ASN n 
1 1268 ALA n 
1 1269 HIS n 
1 1270 VAL n 
1 1271 ILE n 
1 1272 ALA n 
1 1273 VAL n 
1 1274 ILE n 
1 1275 ASP n 
1 1276 ASP n 
1 1277 GLY n 
1 1278 LYS n 
1 1279 VAL n 
1 1280 ALA n 
1 1281 GLU n 
1 1282 GLN n 
1 1283 GLY n 
1 1284 SER n 
1 1285 HIS n 
1 1286 SER n 
1 1287 HIS n 
1 1288 LEU n 
1 1289 LEU n 
1 1290 LYS n 
1 1291 ASN n 
1 1292 HIS n 
1 1293 PRO n 
1 1294 ASP n 
1 1295 GLY n 
1 1296 ILE n 
1 1297 TYR n 
1 1298 ALA n 
1 1299 ARG n 
1 1300 MET n 
1 1301 ILE n 
1 1302 GLN n 
1 1303 LEU n 
1 1304 GLN n 
1 1305 ARG n 
1 1306 PHE n 
1 1307 THR n 
1 1308 HIS n 
1 1309 THR n 
1 1310 GLN n 
1 1311 VAL n 
1 1312 ILE n 
1 1313 GLY n 
1 1314 MET n 
1 1315 THR n 
1 1316 SER n 
1 1317 GLY n 
1 1318 SER n 
1 1319 SER n 
1 1320 SER n 
1 1321 ARG n 
1 1322 VAL n 
1 1323 LYS n 
1 1324 GLU n 
1 1325 ASP n 
1 1326 ASP n 
1 1327 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   1327 
_entity_src_gen.gene_src_common_name               'thale cress' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'ABCB1, MDR1, PGP1, At2g36910, T1J8.9' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Arabidopsis thaliana' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     3702 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            'HEK 293S GnTl-' 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
BLD non-polymer         . Brassinolide    
;(3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)-10-[(2S,3R,4R,5S)-3,4-dihydroxy-5,6-dimethylheptan-2-yl]-5,6-dihydroxy-7a,9a-dime thylhexadecahydro-3H-benzo[c]indeno[5,4-e]oxepin-3-one
;
'C28 H48 O6'     480.677 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    -40  ?    ?   ?   A . n 
A 1 2    ASP 2    -39  ?    ?   ?   A . n 
A 1 3    TYR 3    -38  ?    ?   ?   A . n 
A 1 4    LYS 4    -37  ?    ?   ?   A . n 
A 1 5    ASP 5    -36  ?    ?   ?   A . n 
A 1 6    ASP 6    -35  ?    ?   ?   A . n 
A 1 7    ASP 7    -34  ?    ?   ?   A . n 
A 1 8    ASP 8    -33  ?    ?   ?   A . n 
A 1 9    LYS 9    -32  ?    ?   ?   A . n 
A 1 10   TRP 10   -31  ?    ?   ?   A . n 
A 1 11   SER 11   -30  ?    ?   ?   A . n 
A 1 12   HIS 12   -29  ?    ?   ?   A . n 
A 1 13   PRO 13   -28  ?    ?   ?   A . n 
A 1 14   GLN 14   -27  ?    ?   ?   A . n 
A 1 15   PHE 15   -26  ?    ?   ?   A . n 
A 1 16   GLU 16   -25  ?    ?   ?   A . n 
A 1 17   LYS 17   -24  ?    ?   ?   A . n 
A 1 18   GLY 18   -23  ?    ?   ?   A . n 
A 1 19   GLY 19   -22  ?    ?   ?   A . n 
A 1 20   GLY 20   -21  ?    ?   ?   A . n 
A 1 21   GLY 21   -20  ?    ?   ?   A . n 
A 1 22   SER 22   -19  ?    ?   ?   A . n 
A 1 23   GLY 23   -18  ?    ?   ?   A . n 
A 1 24   GLY 24   -17  ?    ?   ?   A . n 
A 1 25   SER 25   -16  ?    ?   ?   A . n 
A 1 26   ALA 26   -15  ?    ?   ?   A . n 
A 1 27   TRP 27   -14  ?    ?   ?   A . n 
A 1 28   SER 28   -13  ?    ?   ?   A . n 
A 1 29   HIS 29   -12  ?    ?   ?   A . n 
A 1 30   PRO 30   -11  ?    ?   ?   A . n 
A 1 31   GLN 31   -10  ?    ?   ?   A . n 
A 1 32   PHE 32   -9   ?    ?   ?   A . n 
A 1 33   GLU 33   -8   ?    ?   ?   A . n 
A 1 34   LYS 34   -7   ?    ?   ?   A . n 
A 1 35   GLU 35   -6   ?    ?   ?   A . n 
A 1 36   PHE 36   -5   ?    ?   ?   A . n 
A 1 37   LYS 37   -4   ?    ?   ?   A . n 
A 1 38   GLY 38   -3   ?    ?   ?   A . n 
A 1 39   LEU 39   -2   ?    ?   ?   A . n 
A 1 40   VAL 40   -1   ?    ?   ?   A . n 
A 1 41   ASP 41   0    ?    ?   ?   A . n 
A 1 42   MET 42   1    ?    ?   ?   A . n 
A 1 43   ASP 43   2    ?    ?   ?   A . n 
A 1 44   ASN 44   3    ?    ?   ?   A . n 
A 1 45   ASP 45   4    ?    ?   ?   A . n 
A 1 46   GLY 46   5    ?    ?   ?   A . n 
A 1 47   GLY 47   6    ?    ?   ?   A . n 
A 1 48   ALA 48   7    ?    ?   ?   A . n 
A 1 49   PRO 49   8    ?    ?   ?   A . n 
A 1 50   PRO 50   9    ?    ?   ?   A . n 
A 1 51   PRO 51   10   ?    ?   ?   A . n 
A 1 52   PRO 52   11   ?    ?   ?   A . n 
A 1 53   PRO 53   12   ?    ?   ?   A . n 
A 1 54   THR 54   13   ?    ?   ?   A . n 
A 1 55   LEU 55   14   ?    ?   ?   A . n 
A 1 56   VAL 56   15   ?    ?   ?   A . n 
A 1 57   VAL 57   16   ?    ?   ?   A . n 
A 1 58   GLU 58   17   ?    ?   ?   A . n 
A 1 59   GLU 59   18   ?    ?   ?   A . n 
A 1 60   PRO 60   19   ?    ?   ?   A . n 
A 1 61   LYS 61   20   ?    ?   ?   A . n 
A 1 62   LYS 62   21   ?    ?   ?   A . n 
A 1 63   ALA 63   22   ?    ?   ?   A . n 
A 1 64   GLU 64   23   23   GLU GLU A . n 
A 1 65   ILE 65   24   24   ILE ILE A . n 
A 1 66   ARG 66   25   25   ARG ARG A . n 
A 1 67   GLY 67   26   26   GLY GLY A . n 
A 1 68   VAL 68   27   27   VAL VAL A . n 
A 1 69   ALA 69   28   28   ALA ALA A . n 
A 1 70   PHE 70   29   29   PHE PHE A . n 
A 1 71   LYS 71   30   30   LYS LYS A . n 
A 1 72   GLU 72   31   31   GLU GLU A . n 
A 1 73   LEU 73   32   32   LEU LEU A . n 
A 1 74   PHE 74   33   33   PHE PHE A . n 
A 1 75   ARG 75   34   34   ARG ARG A . n 
A 1 76   PHE 76   35   35   PHE PHE A . n 
A 1 77   ALA 77   36   36   ALA ALA A . n 
A 1 78   ASP 78   37   37   ASP ASP A . n 
A 1 79   GLY 79   38   38   GLY GLY A . n 
A 1 80   LEU 80   39   39   LEU LEU A . n 
A 1 81   ASP 81   40   40   ASP ASP A . n 
A 1 82   TYR 82   41   41   TYR TYR A . n 
A 1 83   VAL 83   42   42   VAL VAL A . n 
A 1 84   LEU 84   43   43   LEU LEU A . n 
A 1 85   MET 85   44   44   MET MET A . n 
A 1 86   GLY 86   45   45   GLY GLY A . n 
A 1 87   ILE 87   46   46   ILE ILE A . n 
A 1 88   GLY 88   47   47   GLY GLY A . n 
A 1 89   SER 89   48   48   SER SER A . n 
A 1 90   VAL 90   49   49   VAL VAL A . n 
A 1 91   GLY 91   50   50   GLY GLY A . n 
A 1 92   ALA 92   51   51   ALA ALA A . n 
A 1 93   PHE 93   52   52   PHE PHE A . n 
A 1 94   VAL 94   53   53   VAL VAL A . n 
A 1 95   HIS 95   54   54   HIS HIS A . n 
A 1 96   GLY 96   55   55   GLY GLY A . n 
A 1 97   CYS 97   56   56   CYS CYS A . n 
A 1 98   SER 98   57   57   SER SER A . n 
A 1 99   LEU 99   58   58   LEU LEU A . n 
A 1 100  PRO 100  59   59   PRO PRO A . n 
A 1 101  LEU 101  60   60   LEU LEU A . n 
A 1 102  PHE 102  61   61   PHE PHE A . n 
A 1 103  LEU 103  62   62   LEU LEU A . n 
A 1 104  ARG 104  63   63   ARG ARG A . n 
A 1 105  PHE 105  64   64   PHE PHE A . n 
A 1 106  PHE 106  65   65   PHE PHE A . n 
A 1 107  ALA 107  66   66   ALA ALA A . n 
A 1 108  ASP 108  67   67   ASP ASP A . n 
A 1 109  LEU 109  68   68   LEU LEU A . n 
A 1 110  VAL 110  69   69   VAL VAL A . n 
A 1 111  ASN 111  70   70   ASN ASN A . n 
A 1 112  SER 112  71   71   SER SER A . n 
A 1 113  PHE 113  72   72   PHE PHE A . n 
A 1 114  GLY 114  73   73   GLY GLY A . n 
A 1 115  SER 115  74   74   SER SER A . n 
A 1 116  ASN 116  75   75   ASN ASN A . n 
A 1 117  SER 117  76   76   SER SER A . n 
A 1 118  ASN 118  77   77   ASN ASN A . n 
A 1 119  ASN 119  78   78   ASN ASN A . n 
A 1 120  VAL 120  79   79   VAL VAL A . n 
A 1 121  GLU 121  80   80   GLU GLU A . n 
A 1 122  LYS 122  81   81   LYS LYS A . n 
A 1 123  MET 123  82   82   MET MET A . n 
A 1 124  MET 124  83   83   MET MET A . n 
A 1 125  GLU 125  84   84   GLU GLU A . n 
A 1 126  GLU 126  85   85   GLU GLU A . n 
A 1 127  VAL 127  86   86   VAL VAL A . n 
A 1 128  LEU 128  87   87   LEU LEU A . n 
A 1 129  LYS 129  88   88   LYS LYS A . n 
A 1 130  TYR 130  89   89   TYR TYR A . n 
A 1 131  ALA 131  90   90   ALA ALA A . n 
A 1 132  LEU 132  91   91   LEU LEU A . n 
A 1 133  TYR 133  92   92   TYR TYR A . n 
A 1 134  PHE 134  93   93   PHE PHE A . n 
A 1 135  LEU 135  94   94   LEU LEU A . n 
A 1 136  VAL 136  95   95   VAL VAL A . n 
A 1 137  VAL 137  96   96   VAL VAL A . n 
A 1 138  GLY 138  97   97   GLY GLY A . n 
A 1 139  ALA 139  98   98   ALA ALA A . n 
A 1 140  ALA 140  99   99   ALA ALA A . n 
A 1 141  ILE 141  100  100  ILE ILE A . n 
A 1 142  TRP 142  101  101  TRP TRP A . n 
A 1 143  ALA 143  102  102  ALA ALA A . n 
A 1 144  SER 144  103  103  SER SER A . n 
A 1 145  SER 145  104  104  SER SER A . n 
A 1 146  TRP 146  105  105  TRP TRP A . n 
A 1 147  ALA 147  106  106  ALA ALA A . n 
A 1 148  GLU 148  107  107  GLU GLU A . n 
A 1 149  ILE 149  108  108  ILE ILE A . n 
A 1 150  SER 150  109  109  SER SER A . n 
A 1 151  CYS 151  110  110  CYS CYS A . n 
A 1 152  TRP 152  111  111  TRP TRP A . n 
A 1 153  MET 153  112  112  MET MET A . n 
A 1 154  TRP 154  113  113  TRP TRP A . n 
A 1 155  SER 155  114  114  SER SER A . n 
A 1 156  GLY 156  115  115  GLY GLY A . n 
A 1 157  GLU 157  116  116  GLU GLU A . n 
A 1 158  ARG 158  117  117  ARG ARG A . n 
A 1 159  GLN 159  118  118  GLN GLN A . n 
A 1 160  THR 160  119  119  THR THR A . n 
A 1 161  THR 161  120  120  THR THR A . n 
A 1 162  LYS 162  121  121  LYS LYS A . n 
A 1 163  MET 163  122  122  MET MET A . n 
A 1 164  ARG 164  123  123  ARG ARG A . n 
A 1 165  ILE 165  124  124  ILE ILE A . n 
A 1 166  LYS 166  125  125  LYS LYS A . n 
A 1 167  TYR 167  126  126  TYR TYR A . n 
A 1 168  LEU 168  127  127  LEU LEU A . n 
A 1 169  GLU 169  128  128  GLU GLU A . n 
A 1 170  ALA 170  129  129  ALA ALA A . n 
A 1 171  ALA 171  130  130  ALA ALA A . n 
A 1 172  LEU 172  131  131  LEU LEU A . n 
A 1 173  ASN 173  132  132  ASN ASN A . n 
A 1 174  GLN 174  133  133  GLN GLN A . n 
A 1 175  ASP 175  134  134  ASP ASP A . n 
A 1 176  ILE 176  135  135  ILE ILE A . n 
A 1 177  GLN 177  136  136  GLN GLN A . n 
A 1 178  PHE 178  137  137  PHE PHE A . n 
A 1 179  PHE 179  138  138  PHE PHE A . n 
A 1 180  ASP 180  139  139  ASP ASP A . n 
A 1 181  THR 181  140  140  THR THR A . n 
A 1 182  GLU 182  141  141  GLU GLU A . n 
A 1 183  VAL 183  142  142  VAL VAL A . n 
A 1 184  ARG 184  143  143  ARG ARG A . n 
A 1 185  THR 185  144  144  THR THR A . n 
A 1 186  SER 186  145  145  SER SER A . n 
A 1 187  ASP 187  146  146  ASP ASP A . n 
A 1 188  VAL 188  147  147  VAL VAL A . n 
A 1 189  VAL 189  148  148  VAL VAL A . n 
A 1 190  PHE 190  149  149  PHE PHE A . n 
A 1 191  ALA 191  150  150  ALA ALA A . n 
A 1 192  ILE 192  151  151  ILE ILE A . n 
A 1 193  ASN 193  152  152  ASN ASN A . n 
A 1 194  THR 194  153  153  THR THR A . n 
A 1 195  ASP 195  154  154  ASP ASP A . n 
A 1 196  ALA 196  155  155  ALA ALA A . n 
A 1 197  VAL 197  156  156  VAL VAL A . n 
A 1 198  MET 198  157  157  MET MET A . n 
A 1 199  VAL 199  158  158  VAL VAL A . n 
A 1 200  GLN 200  159  159  GLN GLN A . n 
A 1 201  ASP 201  160  160  ASP ASP A . n 
A 1 202  ALA 202  161  161  ALA ALA A . n 
A 1 203  ILE 203  162  162  ILE ILE A . n 
A 1 204  SER 204  163  163  SER SER A . n 
A 1 205  GLU 205  164  164  GLU GLU A . n 
A 1 206  LYS 206  165  165  LYS LYS A . n 
A 1 207  LEU 207  166  166  LEU LEU A . n 
A 1 208  GLY 208  167  167  GLY GLY A . n 
A 1 209  ASN 209  168  168  ASN ASN A . n 
A 1 210  PHE 210  169  169  PHE PHE A . n 
A 1 211  ILE 211  170  170  ILE ILE A . n 
A 1 212  HIS 212  171  171  HIS HIS A . n 
A 1 213  TYR 213  172  172  TYR TYR A . n 
A 1 214  MET 214  173  173  MET MET A . n 
A 1 215  ALA 215  174  174  ALA ALA A . n 
A 1 216  THR 216  175  175  THR THR A . n 
A 1 217  PHE 217  176  176  PHE PHE A . n 
A 1 218  VAL 218  177  177  VAL VAL A . n 
A 1 219  SER 219  178  178  SER SER A . n 
A 1 220  GLY 220  179  179  GLY GLY A . n 
A 1 221  PHE 221  180  180  PHE PHE A . n 
A 1 222  ILE 222  181  181  ILE ILE A . n 
A 1 223  VAL 223  182  182  VAL VAL A . n 
A 1 224  GLY 224  183  183  GLY GLY A . n 
A 1 225  PHE 225  184  184  PHE PHE A . n 
A 1 226  THR 226  185  185  THR THR A . n 
A 1 227  ALA 227  186  186  ALA ALA A . n 
A 1 228  VAL 228  187  187  VAL VAL A . n 
A 1 229  TRP 229  188  188  TRP TRP A . n 
A 1 230  GLN 230  189  189  GLN GLN A . n 
A 1 231  LEU 231  190  190  LEU LEU A . n 
A 1 232  ALA 232  191  191  ALA ALA A . n 
A 1 233  LEU 233  192  192  LEU LEU A . n 
A 1 234  VAL 234  193  193  VAL VAL A . n 
A 1 235  THR 235  194  194  THR THR A . n 
A 1 236  LEU 236  195  195  LEU LEU A . n 
A 1 237  ALA 237  196  196  ALA ALA A . n 
A 1 238  VAL 238  197  197  VAL VAL A . n 
A 1 239  VAL 239  198  198  VAL VAL A . n 
A 1 240  PRO 240  199  199  PRO PRO A . n 
A 1 241  LEU 241  200  200  LEU LEU A . n 
A 1 242  ILE 242  201  201  ILE ILE A . n 
A 1 243  ALA 243  202  202  ALA ALA A . n 
A 1 244  VAL 244  203  203  VAL VAL A . n 
A 1 245  ILE 245  204  204  ILE ILE A . n 
A 1 246  GLY 246  205  205  GLY GLY A . n 
A 1 247  GLY 247  206  206  GLY GLY A . n 
A 1 248  ILE 248  207  207  ILE ILE A . n 
A 1 249  HIS 249  208  208  HIS HIS A . n 
A 1 250  THR 250  209  209  THR THR A . n 
A 1 251  THR 251  210  210  THR THR A . n 
A 1 252  THR 252  211  211  THR THR A . n 
A 1 253  LEU 253  212  212  LEU LEU A . n 
A 1 254  SER 254  213  213  SER SER A . n 
A 1 255  LYS 255  214  214  LYS LYS A . n 
A 1 256  LEU 256  215  215  LEU LEU A . n 
A 1 257  SER 257  216  216  SER SER A . n 
A 1 258  ASN 258  217  217  ASN ASN A . n 
A 1 259  LYS 259  218  218  LYS LYS A . n 
A 1 260  SER 260  219  219  SER SER A . n 
A 1 261  GLN 261  220  220  GLN GLN A . n 
A 1 262  GLU 262  221  221  GLU GLU A . n 
A 1 263  SER 263  222  222  SER SER A . n 
A 1 264  LEU 264  223  223  LEU LEU A . n 
A 1 265  SER 265  224  224  SER SER A . n 
A 1 266  GLN 266  225  225  GLN GLN A . n 
A 1 267  ALA 267  226  226  ALA ALA A . n 
A 1 268  GLY 268  227  227  GLY GLY A . n 
A 1 269  ASN 269  228  228  ASN ASN A . n 
A 1 270  ILE 270  229  229  ILE ILE A . n 
A 1 271  VAL 271  230  230  VAL VAL A . n 
A 1 272  GLU 272  231  231  GLU GLU A . n 
A 1 273  GLN 273  232  232  GLN GLN A . n 
A 1 274  THR 274  233  233  THR THR A . n 
A 1 275  VAL 275  234  234  VAL VAL A . n 
A 1 276  VAL 276  235  235  VAL VAL A . n 
A 1 277  GLN 277  236  236  GLN GLN A . n 
A 1 278  ILE 278  237  237  ILE ILE A . n 
A 1 279  ARG 279  238  238  ARG ARG A . n 
A 1 280  VAL 280  239  239  VAL VAL A . n 
A 1 281  VAL 281  240  240  VAL VAL A . n 
A 1 282  MET 282  241  241  MET MET A . n 
A 1 283  ALA 283  242  242  ALA ALA A . n 
A 1 284  PHE 284  243  243  PHE PHE A . n 
A 1 285  VAL 285  244  244  VAL VAL A . n 
A 1 286  GLY 286  245  245  GLY GLY A . n 
A 1 287  GLU 287  246  246  GLU GLU A . n 
A 1 288  SER 288  247  247  SER SER A . n 
A 1 289  ARG 289  248  248  ARG ARG A . n 
A 1 290  ALA 290  249  249  ALA ALA A . n 
A 1 291  SER 291  250  250  SER SER A . n 
A 1 292  GLN 292  251  251  GLN GLN A . n 
A 1 293  ALA 293  252  252  ALA ALA A . n 
A 1 294  TYR 294  253  253  TYR TYR A . n 
A 1 295  SER 295  254  254  SER SER A . n 
A 1 296  SER 296  255  255  SER SER A . n 
A 1 297  ALA 297  256  256  ALA ALA A . n 
A 1 298  LEU 298  257  257  LEU LEU A . n 
A 1 299  LYS 299  258  258  LYS LYS A . n 
A 1 300  ILE 300  259  259  ILE ILE A . n 
A 1 301  ALA 301  260  260  ALA ALA A . n 
A 1 302  GLN 302  261  261  GLN GLN A . n 
A 1 303  LYS 303  262  262  LYS LYS A . n 
A 1 304  LEU 304  263  263  LEU LEU A . n 
A 1 305  GLY 305  264  264  GLY GLY A . n 
A 1 306  TYR 306  265  265  TYR TYR A . n 
A 1 307  LYS 307  266  266  LYS LYS A . n 
A 1 308  THR 308  267  267  THR THR A . n 
A 1 309  GLY 309  268  268  GLY GLY A . n 
A 1 310  LEU 310  269  269  LEU LEU A . n 
A 1 311  ALA 311  270  270  ALA ALA A . n 
A 1 312  LYS 312  271  271  LYS LYS A . n 
A 1 313  GLY 313  272  272  GLY GLY A . n 
A 1 314  MET 314  273  273  MET MET A . n 
A 1 315  GLY 315  274  274  GLY GLY A . n 
A 1 316  LEU 316  275  275  LEU LEU A . n 
A 1 317  GLY 317  276  276  GLY GLY A . n 
A 1 318  ALA 318  277  277  ALA ALA A . n 
A 1 319  THR 319  278  278  THR THR A . n 
A 1 320  TYR 320  279  279  TYR TYR A . n 
A 1 321  PHE 321  280  280  PHE PHE A . n 
A 1 322  VAL 322  281  281  VAL VAL A . n 
A 1 323  VAL 323  282  282  VAL VAL A . n 
A 1 324  PHE 324  283  283  PHE PHE A . n 
A 1 325  CYS 325  284  284  CYS CYS A . n 
A 1 326  CYS 326  285  285  CYS CYS A . n 
A 1 327  TYR 327  286  286  TYR TYR A . n 
A 1 328  ALA 328  287  287  ALA ALA A . n 
A 1 329  LEU 329  288  288  LEU LEU A . n 
A 1 330  LEU 330  289  289  LEU LEU A . n 
A 1 331  LEU 331  290  290  LEU LEU A . n 
A 1 332  TRP 332  291  291  TRP TRP A . n 
A 1 333  TYR 333  292  292  TYR TYR A . n 
A 1 334  GLY 334  293  293  GLY GLY A . n 
A 1 335  GLY 335  294  294  GLY GLY A . n 
A 1 336  TYR 336  295  295  TYR TYR A . n 
A 1 337  LEU 337  296  296  LEU LEU A . n 
A 1 338  VAL 338  297  297  VAL VAL A . n 
A 1 339  ARG 339  298  298  ARG ARG A . n 
A 1 340  HIS 340  299  299  HIS HIS A . n 
A 1 341  HIS 341  300  300  HIS HIS A . n 
A 1 342  LEU 342  301  301  LEU LEU A . n 
A 1 343  THR 343  302  302  THR THR A . n 
A 1 344  ASN 344  303  303  ASN ASN A . n 
A 1 345  GLY 345  304  304  GLY GLY A . n 
A 1 346  GLY 346  305  305  GLY GLY A . n 
A 1 347  LEU 347  306  306  LEU LEU A . n 
A 1 348  ALA 348  307  307  ALA ALA A . n 
A 1 349  ILE 349  308  308  ILE ILE A . n 
A 1 350  ALA 350  309  309  ALA ALA A . n 
A 1 351  THR 351  310  310  THR THR A . n 
A 1 352  MET 352  311  311  MET MET A . n 
A 1 353  PHE 353  312  312  PHE PHE A . n 
A 1 354  ALA 354  313  313  ALA ALA A . n 
A 1 355  VAL 355  314  314  VAL VAL A . n 
A 1 356  MET 356  315  315  MET MET A . n 
A 1 357  ILE 357  316  316  ILE ILE A . n 
A 1 358  GLY 358  317  317  GLY GLY A . n 
A 1 359  GLY 359  318  318  GLY GLY A . n 
A 1 360  LEU 360  319  319  LEU LEU A . n 
A 1 361  ALA 361  320  320  ALA ALA A . n 
A 1 362  LEU 362  321  321  LEU LEU A . n 
A 1 363  GLY 363  322  322  GLY GLY A . n 
A 1 364  GLN 364  323  323  GLN GLN A . n 
A 1 365  SER 365  324  324  SER SER A . n 
A 1 366  ALA 366  325  325  ALA ALA A . n 
A 1 367  PRO 367  326  326  PRO PRO A . n 
A 1 368  SER 368  327  327  SER SER A . n 
A 1 369  MET 369  328  328  MET MET A . n 
A 1 370  ALA 370  329  329  ALA ALA A . n 
A 1 371  ALA 371  330  330  ALA ALA A . n 
A 1 372  PHE 372  331  331  PHE PHE A . n 
A 1 373  ALA 373  332  332  ALA ALA A . n 
A 1 374  LYS 374  333  333  LYS LYS A . n 
A 1 375  ALA 375  334  334  ALA ALA A . n 
A 1 376  LYS 376  335  335  LYS LYS A . n 
A 1 377  VAL 377  336  336  VAL VAL A . n 
A 1 378  ALA 378  337  337  ALA ALA A . n 
A 1 379  ALA 379  338  338  ALA ALA A . n 
A 1 380  ALA 380  339  339  ALA ALA A . n 
A 1 381  LYS 381  340  340  LYS LYS A . n 
A 1 382  ILE 382  341  341  ILE ILE A . n 
A 1 383  PHE 383  342  342  PHE PHE A . n 
A 1 384  ARG 384  343  343  ARG ARG A . n 
A 1 385  ILE 385  344  344  ILE ILE A . n 
A 1 386  ILE 386  345  345  ILE ILE A . n 
A 1 387  ASP 387  346  346  ASP ASP A . n 
A 1 388  HIS 388  347  347  HIS HIS A . n 
A 1 389  LYS 389  348  348  LYS LYS A . n 
A 1 390  PRO 390  349  349  PRO PRO A . n 
A 1 391  THR 391  350  350  THR THR A . n 
A 1 392  ILE 392  351  351  ILE ILE A . n 
A 1 393  GLU 393  352  352  GLU GLU A . n 
A 1 394  ARG 394  353  353  ARG ARG A . n 
A 1 395  ASN 395  354  354  ASN ASN A . n 
A 1 396  SER 396  355  355  SER SER A . n 
A 1 397  GLU 397  356  356  GLU GLU A . n 
A 1 398  SER 398  357  357  SER SER A . n 
A 1 399  GLY 399  358  358  GLY GLY A . n 
A 1 400  VAL 400  359  359  VAL VAL A . n 
A 1 401  GLU 401  360  360  GLU GLU A . n 
A 1 402  LEU 402  361  361  LEU LEU A . n 
A 1 403  ASP 403  362  362  ASP ASP A . n 
A 1 404  SER 404  363  363  SER SER A . n 
A 1 405  VAL 405  364  364  VAL VAL A . n 
A 1 406  THR 406  365  365  THR THR A . n 
A 1 407  GLY 407  366  366  GLY GLY A . n 
A 1 408  LEU 408  367  367  LEU LEU A . n 
A 1 409  VAL 409  368  368  VAL VAL A . n 
A 1 410  GLU 410  369  369  GLU GLU A . n 
A 1 411  LEU 411  370  370  LEU LEU A . n 
A 1 412  LYS 412  371  371  LYS LYS A . n 
A 1 413  ASN 413  372  372  ASN ASN A . n 
A 1 414  VAL 414  373  373  VAL VAL A . n 
A 1 415  ASP 415  374  374  ASP ASP A . n 
A 1 416  PHE 416  375  375  PHE PHE A . n 
A 1 417  SER 417  376  376  SER SER A . n 
A 1 418  TYR 418  377  377  TYR TYR A . n 
A 1 419  PRO 419  378  378  PRO PRO A . n 
A 1 420  SER 420  379  379  SER SER A . n 
A 1 421  ARG 421  380  380  ARG ARG A . n 
A 1 422  PRO 422  381  381  PRO PRO A . n 
A 1 423  ASP 423  382  382  ASP ASP A . n 
A 1 424  VAL 424  383  383  VAL VAL A . n 
A 1 425  LYS 425  384  384  LYS LYS A . n 
A 1 426  ILE 426  385  385  ILE ILE A . n 
A 1 427  LEU 427  386  386  LEU LEU A . n 
A 1 428  ASN 428  387  387  ASN ASN A . n 
A 1 429  ASN 429  388  388  ASN ASN A . n 
A 1 430  PHE 430  389  389  PHE PHE A . n 
A 1 431  CYS 431  390  390  CYS CYS A . n 
A 1 432  LEU 432  391  391  LEU LEU A . n 
A 1 433  SER 433  392  392  SER SER A . n 
A 1 434  VAL 434  393  393  VAL VAL A . n 
A 1 435  PRO 435  394  394  PRO PRO A . n 
A 1 436  ALA 436  395  395  ALA ALA A . n 
A 1 437  GLY 437  396  396  GLY GLY A . n 
A 1 438  LYS 438  397  397  LYS LYS A . n 
A 1 439  THR 439  398  398  THR THR A . n 
A 1 440  ILE 440  399  399  ILE ILE A . n 
A 1 441  ALA 441  400  400  ALA ALA A . n 
A 1 442  LEU 442  401  401  LEU LEU A . n 
A 1 443  VAL 443  402  402  VAL VAL A . n 
A 1 444  GLY 444  403  403  GLY GLY A . n 
A 1 445  SER 445  404  404  SER SER A . n 
A 1 446  SER 446  405  405  SER SER A . n 
A 1 447  GLY 447  406  406  GLY GLY A . n 
A 1 448  SER 448  407  407  SER SER A . n 
A 1 449  GLY 449  408  408  GLY GLY A . n 
A 1 450  LYS 450  409  409  LYS LYS A . n 
A 1 451  SER 451  410  410  SER SER A . n 
A 1 452  THR 452  411  411  THR THR A . n 
A 1 453  VAL 453  412  412  VAL VAL A . n 
A 1 454  VAL 454  413  413  VAL VAL A . n 
A 1 455  SER 455  414  414  SER SER A . n 
A 1 456  LEU 456  415  415  LEU LEU A . n 
A 1 457  ILE 457  416  416  ILE ILE A . n 
A 1 458  GLU 458  417  417  GLU GLU A . n 
A 1 459  ARG 459  418  418  ARG ARG A . n 
A 1 460  PHE 460  419  419  PHE PHE A . n 
A 1 461  TYR 461  420  420  TYR TYR A . n 
A 1 462  ASP 462  421  421  ASP ASP A . n 
A 1 463  PRO 463  422  422  PRO PRO A . n 
A 1 464  ASN 464  423  423  ASN ASN A . n 
A 1 465  SER 465  424  424  SER SER A . n 
A 1 466  GLY 466  425  425  GLY GLY A . n 
A 1 467  GLN 467  426  426  GLN GLN A . n 
A 1 468  VAL 468  427  427  VAL VAL A . n 
A 1 469  LEU 469  428  428  LEU LEU A . n 
A 1 470  LEU 470  429  429  LEU LEU A . n 
A 1 471  ASP 471  430  430  ASP ASP A . n 
A 1 472  GLY 472  431  431  GLY GLY A . n 
A 1 473  GLN 473  432  432  GLN GLN A . n 
A 1 474  ASP 474  433  433  ASP ASP A . n 
A 1 475  LEU 475  434  434  LEU LEU A . n 
A 1 476  LYS 476  435  435  LYS LYS A . n 
A 1 477  THR 477  436  436  THR THR A . n 
A 1 478  LEU 478  437  437  LEU LEU A . n 
A 1 479  LYS 479  438  438  LYS LYS A . n 
A 1 480  LEU 480  439  439  LEU LEU A . n 
A 1 481  ARG 481  440  440  ARG ARG A . n 
A 1 482  TRP 482  441  441  TRP TRP A . n 
A 1 483  LEU 483  442  442  LEU LEU A . n 
A 1 484  ARG 484  443  443  ARG ARG A . n 
A 1 485  GLN 485  444  444  GLN GLN A . n 
A 1 486  GLN 486  445  445  GLN GLN A . n 
A 1 487  ILE 487  446  446  ILE ILE A . n 
A 1 488  GLY 488  447  447  GLY GLY A . n 
A 1 489  LEU 489  448  448  LEU LEU A . n 
A 1 490  VAL 490  449  449  VAL VAL A . n 
A 1 491  SER 491  450  450  SER SER A . n 
A 1 492  GLN 492  451  451  GLN GLN A . n 
A 1 493  GLU 493  452  452  GLU GLU A . n 
A 1 494  PRO 494  453  453  PRO PRO A . n 
A 1 495  ALA 495  454  454  ALA ALA A . n 
A 1 496  LEU 496  455  455  LEU LEU A . n 
A 1 497  PHE 497  456  456  PHE PHE A . n 
A 1 498  ALA 498  457  457  ALA ALA A . n 
A 1 499  THR 499  458  458  THR THR A . n 
A 1 500  SER 500  459  459  SER SER A . n 
A 1 501  ILE 501  460  460  ILE ILE A . n 
A 1 502  LYS 502  461  461  LYS LYS A . n 
A 1 503  GLU 503  462  462  GLU GLU A . n 
A 1 504  ASN 504  463  463  ASN ASN A . n 
A 1 505  ILE 505  464  464  ILE ILE A . n 
A 1 506  LEU 506  465  465  LEU LEU A . n 
A 1 507  LEU 507  466  466  LEU LEU A . n 
A 1 508  GLY 508  467  467  GLY GLY A . n 
A 1 509  ARG 509  468  468  ARG ARG A . n 
A 1 510  PRO 510  469  469  PRO PRO A . n 
A 1 511  ASP 511  470  470  ASP ASP A . n 
A 1 512  ALA 512  471  471  ALA ALA A . n 
A 1 513  ASP 513  472  472  ASP ASP A . n 
A 1 514  GLN 514  473  473  GLN GLN A . n 
A 1 515  VAL 515  474  474  VAL VAL A . n 
A 1 516  GLU 516  475  475  GLU GLU A . n 
A 1 517  ILE 517  476  476  ILE ILE A . n 
A 1 518  GLU 518  477  477  GLU GLU A . n 
A 1 519  GLU 519  478  478  GLU GLU A . n 
A 1 520  ALA 520  479  479  ALA ALA A . n 
A 1 521  ALA 521  480  480  ALA ALA A . n 
A 1 522  ARG 522  481  481  ARG ARG A . n 
A 1 523  VAL 523  482  482  VAL VAL A . n 
A 1 524  ALA 524  483  483  ALA ALA A . n 
A 1 525  ASN 525  484  484  ASN ASN A . n 
A 1 526  ALA 526  485  485  ALA ALA A . n 
A 1 527  HIS 527  486  486  HIS HIS A . n 
A 1 528  SER 528  487  487  SER SER A . n 
A 1 529  PHE 529  488  488  PHE PHE A . n 
A 1 530  ILE 530  489  489  ILE ILE A . n 
A 1 531  ILE 531  490  490  ILE ILE A . n 
A 1 532  LYS 532  491  491  LYS LYS A . n 
A 1 533  LEU 533  492  492  LEU LEU A . n 
A 1 534  PRO 534  493  493  PRO PRO A . n 
A 1 535  ASP 535  494  494  ASP ASP A . n 
A 1 536  GLY 536  495  495  GLY GLY A . n 
A 1 537  PHE 537  496  496  PHE PHE A . n 
A 1 538  ASP 538  497  497  ASP ASP A . n 
A 1 539  THR 539  498  498  THR THR A . n 
A 1 540  GLN 540  499  499  GLN GLN A . n 
A 1 541  VAL 541  500  500  VAL VAL A . n 
A 1 542  GLY 542  501  501  GLY GLY A . n 
A 1 543  GLU 543  502  502  GLU GLU A . n 
A 1 544  ARG 544  503  503  ARG ARG A . n 
A 1 545  GLY 545  504  504  GLY GLY A . n 
A 1 546  LEU 546  505  505  LEU LEU A . n 
A 1 547  GLN 547  506  506  GLN GLN A . n 
A 1 548  LEU 548  507  507  LEU LEU A . n 
A 1 549  SER 549  508  508  SER SER A . n 
A 1 550  GLY 550  509  509  GLY GLY A . n 
A 1 551  GLY 551  510  510  GLY GLY A . n 
A 1 552  GLN 552  511  511  GLN GLN A . n 
A 1 553  LYS 553  512  512  LYS LYS A . n 
A 1 554  GLN 554  513  513  GLN GLN A . n 
A 1 555  ARG 555  514  514  ARG ARG A . n 
A 1 556  ILE 556  515  515  ILE ILE A . n 
A 1 557  ALA 557  516  516  ALA ALA A . n 
A 1 558  ILE 558  517  517  ILE ILE A . n 
A 1 559  ALA 559  518  518  ALA ALA A . n 
A 1 560  ARG 560  519  519  ARG ARG A . n 
A 1 561  ALA 561  520  520  ALA ALA A . n 
A 1 562  MET 562  521  521  MET MET A . n 
A 1 563  LEU 563  522  522  LEU LEU A . n 
A 1 564  LYS 564  523  523  LYS LYS A . n 
A 1 565  ASN 565  524  524  ASN ASN A . n 
A 1 566  PRO 566  525  525  PRO PRO A . n 
A 1 567  ALA 567  526  526  ALA ALA A . n 
A 1 568  ILE 568  527  527  ILE ILE A . n 
A 1 569  LEU 569  528  528  LEU LEU A . n 
A 1 570  LEU 570  529  529  LEU LEU A . n 
A 1 571  LEU 571  530  530  LEU LEU A . n 
A 1 572  ASP 572  531  531  ASP ASP A . n 
A 1 573  GLU 573  532  532  GLU GLU A . n 
A 1 574  ALA 574  533  533  ALA ALA A . n 
A 1 575  THR 575  534  534  THR THR A . n 
A 1 576  SER 576  535  535  SER SER A . n 
A 1 577  ALA 577  536  536  ALA ALA A . n 
A 1 578  LEU 578  537  537  LEU LEU A . n 
A 1 579  ASP 579  538  538  ASP ASP A . n 
A 1 580  SER 580  539  539  SER SER A . n 
A 1 581  GLU 581  540  540  GLU GLU A . n 
A 1 582  SER 582  541  541  SER SER A . n 
A 1 583  GLU 583  542  542  GLU GLU A . n 
A 1 584  LYS 584  543  543  LYS LYS A . n 
A 1 585  LEU 585  544  544  LEU LEU A . n 
A 1 586  VAL 586  545  545  VAL VAL A . n 
A 1 587  GLN 587  546  546  GLN GLN A . n 
A 1 588  GLU 588  547  547  GLU GLU A . n 
A 1 589  ALA 589  548  548  ALA ALA A . n 
A 1 590  LEU 590  549  549  LEU LEU A . n 
A 1 591  ASP 591  550  550  ASP ASP A . n 
A 1 592  ARG 592  551  551  ARG ARG A . n 
A 1 593  PHE 593  552  552  PHE PHE A . n 
A 1 594  MET 594  553  553  MET MET A . n 
A 1 595  ILE 595  554  554  ILE ILE A . n 
A 1 596  GLY 596  555  555  GLY GLY A . n 
A 1 597  ARG 597  556  556  ARG ARG A . n 
A 1 598  THR 598  557  557  THR THR A . n 
A 1 599  THR 599  558  558  THR THR A . n 
A 1 600  LEU 600  559  559  LEU LEU A . n 
A 1 601  ILE 601  560  560  ILE ILE A . n 
A 1 602  ILE 602  561  561  ILE ILE A . n 
A 1 603  ALA 603  562  562  ALA ALA A . n 
A 1 604  HIS 604  563  563  HIS HIS A . n 
A 1 605  ARG 605  564  564  ARG ARG A . n 
A 1 606  LEU 606  565  565  LEU LEU A . n 
A 1 607  SER 607  566  566  SER SER A . n 
A 1 608  THR 608  567  567  THR THR A . n 
A 1 609  ILE 609  568  568  ILE ILE A . n 
A 1 610  ARG 610  569  569  ARG ARG A . n 
A 1 611  LYS 611  570  570  LYS LYS A . n 
A 1 612  ALA 612  571  571  ALA ALA A . n 
A 1 613  ASP 613  572  572  ASP ASP A . n 
A 1 614  LEU 614  573  573  LEU LEU A . n 
A 1 615  VAL 615  574  574  VAL VAL A . n 
A 1 616  ALA 616  575  575  ALA ALA A . n 
A 1 617  VAL 617  576  576  VAL VAL A . n 
A 1 618  LEU 618  577  577  LEU LEU A . n 
A 1 619  GLN 619  578  578  GLN GLN A . n 
A 1 620  GLN 620  579  579  GLN GLN A . n 
A 1 621  GLY 621  580  580  GLY GLY A . n 
A 1 622  SER 622  581  581  SER SER A . n 
A 1 623  VAL 623  582  582  VAL VAL A . n 
A 1 624  SER 624  583  583  SER SER A . n 
A 1 625  GLU 625  584  584  GLU GLU A . n 
A 1 626  ILE 626  585  585  ILE ILE A . n 
A 1 627  GLY 627  586  586  GLY GLY A . n 
A 1 628  THR 628  587  587  THR THR A . n 
A 1 629  HIS 629  588  588  HIS HIS A . n 
A 1 630  ASP 630  589  589  ASP ASP A . n 
A 1 631  GLU 631  590  590  GLU GLU A . n 
A 1 632  LEU 632  591  591  LEU LEU A . n 
A 1 633  PHE 633  592  592  PHE PHE A . n 
A 1 634  SER 634  593  593  SER SER A . n 
A 1 635  LYS 635  594  594  LYS LYS A . n 
A 1 636  GLY 636  595  595  GLY GLY A . n 
A 1 637  GLU 637  596  596  GLU GLU A . n 
A 1 638  ASN 638  597  597  ASN ASN A . n 
A 1 639  GLY 639  598  598  GLY GLY A . n 
A 1 640  VAL 640  599  ?    ?   ?   A . n 
A 1 641  TYR 641  600  ?    ?   ?   A . n 
A 1 642  ALA 642  601  ?    ?   ?   A . n 
A 1 643  LYS 643  602  ?    ?   ?   A . n 
A 1 644  LEU 644  603  ?    ?   ?   A . n 
A 1 645  ILE 645  604  ?    ?   ?   A . n 
A 1 646  LYS 646  605  ?    ?   ?   A . n 
A 1 647  MET 647  606  ?    ?   ?   A . n 
A 1 648  GLN 648  607  ?    ?   ?   A . n 
A 1 649  GLU 649  608  ?    ?   ?   A . n 
A 1 650  ALA 650  609  ?    ?   ?   A . n 
A 1 651  ALA 651  610  ?    ?   ?   A . n 
A 1 652  HIS 652  611  ?    ?   ?   A . n 
A 1 653  GLU 653  612  ?    ?   ?   A . n 
A 1 654  THR 654  613  ?    ?   ?   A . n 
A 1 655  ALA 655  614  ?    ?   ?   A . n 
A 1 656  MET 656  615  ?    ?   ?   A . n 
A 1 657  SER 657  616  ?    ?   ?   A . n 
A 1 658  ASN 658  617  ?    ?   ?   A . n 
A 1 659  ALA 659  618  ?    ?   ?   A . n 
A 1 660  ARG 660  619  ?    ?   ?   A . n 
A 1 661  LYS 661  620  ?    ?   ?   A . n 
A 1 662  SER 662  621  ?    ?   ?   A . n 
A 1 663  SER 663  622  ?    ?   ?   A . n 
A 1 664  ALA 664  623  ?    ?   ?   A . n 
A 1 665  ARG 665  624  ?    ?   ?   A . n 
A 1 666  PRO 666  625  ?    ?   ?   A . n 
A 1 667  SER 667  626  ?    ?   ?   A . n 
A 1 668  SER 668  627  ?    ?   ?   A . n 
A 1 669  ALA 669  628  ?    ?   ?   A . n 
A 1 670  ARG 670  629  ?    ?   ?   A . n 
A 1 671  ASN 671  630  ?    ?   ?   A . n 
A 1 672  SER 672  631  ?    ?   ?   A . n 
A 1 673  VAL 673  632  ?    ?   ?   A . n 
A 1 674  SER 674  633  ?    ?   ?   A . n 
A 1 675  SER 675  634  ?    ?   ?   A . n 
A 1 676  PRO 676  635  ?    ?   ?   A . n 
A 1 677  ILE 677  636  ?    ?   ?   A . n 
A 1 678  MET 678  637  ?    ?   ?   A . n 
A 1 679  THR 679  638  ?    ?   ?   A . n 
A 1 680  ARG 680  639  ?    ?   ?   A . n 
A 1 681  ASN 681  640  ?    ?   ?   A . n 
A 1 682  SER 682  641  ?    ?   ?   A . n 
A 1 683  SER 683  642  ?    ?   ?   A . n 
A 1 684  TYR 684  643  ?    ?   ?   A . n 
A 1 685  GLY 685  644  ?    ?   ?   A . n 
A 1 686  ARG 686  645  ?    ?   ?   A . n 
A 1 687  SER 687  646  ?    ?   ?   A . n 
A 1 688  PRO 688  647  ?    ?   ?   A . n 
A 1 689  TYR 689  648  ?    ?   ?   A . n 
A 1 690  SER 690  649  ?    ?   ?   A . n 
A 1 691  ARG 691  650  ?    ?   ?   A . n 
A 1 692  ARG 692  651  ?    ?   ?   A . n 
A 1 693  LEU 693  652  ?    ?   ?   A . n 
A 1 694  SER 694  653  ?    ?   ?   A . n 
A 1 695  ASP 695  654  ?    ?   ?   A . n 
A 1 696  PHE 696  655  ?    ?   ?   A . n 
A 1 697  SER 697  656  ?    ?   ?   A . n 
A 1 698  THR 698  657  ?    ?   ?   A . n 
A 1 699  SER 699  658  ?    ?   ?   A . n 
A 1 700  ASP 700  659  ?    ?   ?   A . n 
A 1 701  PHE 701  660  ?    ?   ?   A . n 
A 1 702  SER 702  661  ?    ?   ?   A . n 
A 1 703  LEU 703  662  ?    ?   ?   A . n 
A 1 704  SER 704  663  ?    ?   ?   A . n 
A 1 705  ILE 705  664  ?    ?   ?   A . n 
A 1 706  ASP 706  665  ?    ?   ?   A . n 
A 1 707  ALA 707  666  ?    ?   ?   A . n 
A 1 708  SER 708  667  ?    ?   ?   A . n 
A 1 709  SER 709  668  ?    ?   ?   A . n 
A 1 710  TYR 710  669  ?    ?   ?   A . n 
A 1 711  PRO 711  670  ?    ?   ?   A . n 
A 1 712  ASN 712  671  ?    ?   ?   A . n 
A 1 713  TYR 713  672  ?    ?   ?   A . n 
A 1 714  ARG 714  673  ?    ?   ?   A . n 
A 1 715  ASN 715  674  ?    ?   ?   A . n 
A 1 716  GLU 716  675  ?    ?   ?   A . n 
A 1 717  LYS 717  676  676  LYS LYS A . n 
A 1 718  LEU 718  677  677  LEU LEU A . n 
A 1 719  ALA 719  678  678  ALA ALA A . n 
A 1 720  PHE 720  679  679  PHE PHE A . n 
A 1 721  LYS 721  680  680  LYS LYS A . n 
A 1 722  ASP 722  681  681  ASP ASP A . n 
A 1 723  GLN 723  682  682  GLN GLN A . n 
A 1 724  ALA 724  683  683  ALA ALA A . n 
A 1 725  ASN 725  684  684  ASN ASN A . n 
A 1 726  SER 726  685  685  SER SER A . n 
A 1 727  PHE 727  686  686  PHE PHE A . n 
A 1 728  TRP 728  687  687  TRP TRP A . n 
A 1 729  ARG 729  688  688  ARG ARG A . n 
A 1 730  LEU 730  689  689  LEU LEU A . n 
A 1 731  ALA 731  690  690  ALA ALA A . n 
A 1 732  LYS 732  691  691  LYS LYS A . n 
A 1 733  MET 733  692  692  MET MET A . n 
A 1 734  ASN 734  693  693  ASN ASN A . n 
A 1 735  SER 735  694  694  SER SER A . n 
A 1 736  PRO 736  695  695  PRO PRO A . n 
A 1 737  GLU 737  696  696  GLU GLU A . n 
A 1 738  TRP 738  697  697  TRP TRP A . n 
A 1 739  LYS 739  698  698  LYS LYS A . n 
A 1 740  TYR 740  699  699  TYR TYR A . n 
A 1 741  ALA 741  700  700  ALA ALA A . n 
A 1 742  LEU 742  701  701  LEU LEU A . n 
A 1 743  LEU 743  702  702  LEU LEU A . n 
A 1 744  GLY 744  703  703  GLY GLY A . n 
A 1 745  SER 745  704  704  SER SER A . n 
A 1 746  VAL 746  705  705  VAL VAL A . n 
A 1 747  GLY 747  706  706  GLY GLY A . n 
A 1 748  SER 748  707  707  SER SER A . n 
A 1 749  VAL 749  708  708  VAL VAL A . n 
A 1 750  ILE 750  709  709  ILE ILE A . n 
A 1 751  CYS 751  710  710  CYS CYS A . n 
A 1 752  GLY 752  711  711  GLY GLY A . n 
A 1 753  SER 753  712  712  SER SER A . n 
A 1 754  LEU 754  713  713  LEU LEU A . n 
A 1 755  SER 755  714  714  SER SER A . n 
A 1 756  ALA 756  715  715  ALA ALA A . n 
A 1 757  PHE 757  716  716  PHE PHE A . n 
A 1 758  PHE 758  717  717  PHE PHE A . n 
A 1 759  ALA 759  718  718  ALA ALA A . n 
A 1 760  TYR 760  719  719  TYR TYR A . n 
A 1 761  VAL 761  720  720  VAL VAL A . n 
A 1 762  LEU 762  721  721  LEU LEU A . n 
A 1 763  SER 763  722  722  SER SER A . n 
A 1 764  ALA 764  723  723  ALA ALA A . n 
A 1 765  VAL 765  724  724  VAL VAL A . n 
A 1 766  LEU 766  725  725  LEU LEU A . n 
A 1 767  SER 767  726  726  SER SER A . n 
A 1 768  VAL 768  727  727  VAL VAL A . n 
A 1 769  TYR 769  728  728  TYR TYR A . n 
A 1 770  TYR 770  729  729  TYR TYR A . n 
A 1 771  ASN 771  730  730  ASN ASN A . n 
A 1 772  PRO 772  731  731  PRO PRO A . n 
A 1 773  ASP 773  732  732  ASP ASP A . n 
A 1 774  HIS 774  733  733  HIS HIS A . n 
A 1 775  GLU 775  734  734  GLU GLU A . n 
A 1 776  TYR 776  735  735  TYR TYR A . n 
A 1 777  MET 777  736  736  MET MET A . n 
A 1 778  ILE 778  737  737  ILE ILE A . n 
A 1 779  LYS 779  738  738  LYS LYS A . n 
A 1 780  GLN 780  739  739  GLN GLN A . n 
A 1 781  ILE 781  740  740  ILE ILE A . n 
A 1 782  ASP 782  741  741  ASP ASP A . n 
A 1 783  LYS 783  742  742  LYS LYS A . n 
A 1 784  TYR 784  743  743  TYR TYR A . n 
A 1 785  CYS 785  744  744  CYS CYS A . n 
A 1 786  TYR 786  745  745  TYR TYR A . n 
A 1 787  LEU 787  746  746  LEU LEU A . n 
A 1 788  LEU 788  747  747  LEU LEU A . n 
A 1 789  ILE 789  748  748  ILE ILE A . n 
A 1 790  GLY 790  749  749  GLY GLY A . n 
A 1 791  LEU 791  750  750  LEU LEU A . n 
A 1 792  SER 792  751  751  SER SER A . n 
A 1 793  SER 793  752  752  SER SER A . n 
A 1 794  ALA 794  753  753  ALA ALA A . n 
A 1 795  ALA 795  754  754  ALA ALA A . n 
A 1 796  LEU 796  755  755  LEU LEU A . n 
A 1 797  VAL 797  756  756  VAL VAL A . n 
A 1 798  PHE 798  757  757  PHE PHE A . n 
A 1 799  ASN 799  758  758  ASN ASN A . n 
A 1 800  THR 800  759  759  THR THR A . n 
A 1 801  LEU 801  760  760  LEU LEU A . n 
A 1 802  GLN 802  761  761  GLN GLN A . n 
A 1 803  HIS 803  762  762  HIS HIS A . n 
A 1 804  SER 804  763  763  SER SER A . n 
A 1 805  PHE 805  764  764  PHE PHE A . n 
A 1 806  TRP 806  765  765  TRP TRP A . n 
A 1 807  ASP 807  766  766  ASP ASP A . n 
A 1 808  ILE 808  767  767  ILE ILE A . n 
A 1 809  VAL 809  768  768  VAL VAL A . n 
A 1 810  GLY 810  769  769  GLY GLY A . n 
A 1 811  GLU 811  770  770  GLU GLU A . n 
A 1 812  ASN 812  771  771  ASN ASN A . n 
A 1 813  LEU 813  772  772  LEU LEU A . n 
A 1 814  THR 814  773  773  THR THR A . n 
A 1 815  LYS 815  774  774  LYS LYS A . n 
A 1 816  ARG 816  775  775  ARG ARG A . n 
A 1 817  VAL 817  776  776  VAL VAL A . n 
A 1 818  ARG 818  777  777  ARG ARG A . n 
A 1 819  GLU 819  778  778  GLU GLU A . n 
A 1 820  LYS 820  779  779  LYS LYS A . n 
A 1 821  MET 821  780  780  MET MET A . n 
A 1 822  LEU 822  781  781  LEU LEU A . n 
A 1 823  SER 823  782  782  SER SER A . n 
A 1 824  ALA 824  783  783  ALA ALA A . n 
A 1 825  VAL 825  784  784  VAL VAL A . n 
A 1 826  LEU 826  785  785  LEU LEU A . n 
A 1 827  LYS 827  786  786  LYS LYS A . n 
A 1 828  ASN 828  787  787  ASN ASN A . n 
A 1 829  GLU 829  788  788  GLU GLU A . n 
A 1 830  MET 830  789  789  MET MET A . n 
A 1 831  ALA 831  790  790  ALA ALA A . n 
A 1 832  TRP 832  791  791  TRP TRP A . n 
A 1 833  PHE 833  792  792  PHE PHE A . n 
A 1 834  ASP 834  793  793  ASP ASP A . n 
A 1 835  GLN 835  794  794  GLN GLN A . n 
A 1 836  GLU 836  795  795  GLU GLU A . n 
A 1 837  GLU 837  796  796  GLU GLU A . n 
A 1 838  ASN 838  797  797  ASN ASN A . n 
A 1 839  GLU 839  798  798  GLU GLU A . n 
A 1 840  SER 840  799  799  SER SER A . n 
A 1 841  ALA 841  800  800  ALA ALA A . n 
A 1 842  ARG 842  801  801  ARG ARG A . n 
A 1 843  ILE 843  802  802  ILE ILE A . n 
A 1 844  ALA 844  803  803  ALA ALA A . n 
A 1 845  ALA 845  804  804  ALA ALA A . n 
A 1 846  ARG 846  805  805  ARG ARG A . n 
A 1 847  LEU 847  806  806  LEU LEU A . n 
A 1 848  ALA 848  807  807  ALA ALA A . n 
A 1 849  LEU 849  808  808  LEU LEU A . n 
A 1 850  ASP 850  809  809  ASP ASP A . n 
A 1 851  ALA 851  810  810  ALA ALA A . n 
A 1 852  ASN 852  811  811  ASN ASN A . n 
A 1 853  ASN 853  812  812  ASN ASN A . n 
A 1 854  VAL 854  813  813  VAL VAL A . n 
A 1 855  ARG 855  814  814  ARG ARG A . n 
A 1 856  SER 856  815  815  SER SER A . n 
A 1 857  ALA 857  816  816  ALA ALA A . n 
A 1 858  ILE 858  817  817  ILE ILE A . n 
A 1 859  GLY 859  818  818  GLY GLY A . n 
A 1 860  ASP 860  819  819  ASP ASP A . n 
A 1 861  ARG 861  820  820  ARG ARG A . n 
A 1 862  ILE 862  821  821  ILE ILE A . n 
A 1 863  SER 863  822  822  SER SER A . n 
A 1 864  VAL 864  823  823  VAL VAL A . n 
A 1 865  ILE 865  824  824  ILE ILE A . n 
A 1 866  VAL 866  825  825  VAL VAL A . n 
A 1 867  GLN 867  826  826  GLN GLN A . n 
A 1 868  ASN 868  827  827  ASN ASN A . n 
A 1 869  THR 869  828  828  THR THR A . n 
A 1 870  ALA 870  829  829  ALA ALA A . n 
A 1 871  LEU 871  830  830  LEU LEU A . n 
A 1 872  MET 872  831  831  MET MET A . n 
A 1 873  LEU 873  832  832  LEU LEU A . n 
A 1 874  VAL 874  833  833  VAL VAL A . n 
A 1 875  ALA 875  834  834  ALA ALA A . n 
A 1 876  CYS 876  835  835  CYS CYS A . n 
A 1 877  THR 877  836  836  THR THR A . n 
A 1 878  ALA 878  837  837  ALA ALA A . n 
A 1 879  GLY 879  838  838  GLY GLY A . n 
A 1 880  PHE 880  839  839  PHE PHE A . n 
A 1 881  VAL 881  840  840  VAL VAL A . n 
A 1 882  LEU 882  841  841  LEU LEU A . n 
A 1 883  GLN 883  842  842  GLN GLN A . n 
A 1 884  TRP 884  843  843  TRP TRP A . n 
A 1 885  ARG 885  844  844  ARG ARG A . n 
A 1 886  LEU 886  845  845  LEU LEU A . n 
A 1 887  ALA 887  846  846  ALA ALA A . n 
A 1 888  LEU 888  847  847  LEU LEU A . n 
A 1 889  VAL 889  848  848  VAL VAL A . n 
A 1 890  LEU 890  849  849  LEU LEU A . n 
A 1 891  VAL 891  850  850  VAL VAL A . n 
A 1 892  ALA 892  851  851  ALA ALA A . n 
A 1 893  VAL 893  852  852  VAL VAL A . n 
A 1 894  PHE 894  853  853  PHE PHE A . n 
A 1 895  PRO 895  854  854  PRO PRO A . n 
A 1 896  VAL 896  855  855  VAL VAL A . n 
A 1 897  VAL 897  856  856  VAL VAL A . n 
A 1 898  VAL 898  857  857  VAL VAL A . n 
A 1 899  ALA 899  858  858  ALA ALA A . n 
A 1 900  ALA 900  859  859  ALA ALA A . n 
A 1 901  THR 901  860  860  THR THR A . n 
A 1 902  VAL 902  861  861  VAL VAL A . n 
A 1 903  LEU 903  862  862  LEU LEU A . n 
A 1 904  GLN 904  863  863  GLN GLN A . n 
A 1 905  LYS 905  864  864  LYS LYS A . n 
A 1 906  MET 906  865  865  MET MET A . n 
A 1 907  PHE 907  866  866  PHE PHE A . n 
A 1 908  MET 908  867  867  MET MET A . n 
A 1 909  THR 909  868  868  THR THR A . n 
A 1 910  GLY 910  869  869  GLY GLY A . n 
A 1 911  PHE 911  870  870  PHE PHE A . n 
A 1 912  SER 912  871  871  SER SER A . n 
A 1 913  GLY 913  872  872  GLY GLY A . n 
A 1 914  ASP 914  873  873  ASP ASP A . n 
A 1 915  LEU 915  874  874  LEU LEU A . n 
A 1 916  GLU 916  875  875  GLU GLU A . n 
A 1 917  ALA 917  876  876  ALA ALA A . n 
A 1 918  ALA 918  877  877  ALA ALA A . n 
A 1 919  HIS 919  878  878  HIS HIS A . n 
A 1 920  ALA 920  879  879  ALA ALA A . n 
A 1 921  LYS 921  880  880  LYS LYS A . n 
A 1 922  GLY 922  881  881  GLY GLY A . n 
A 1 923  THR 923  882  882  THR THR A . n 
A 1 924  GLN 924  883  883  GLN GLN A . n 
A 1 925  LEU 925  884  884  LEU LEU A . n 
A 1 926  ALA 926  885  885  ALA ALA A . n 
A 1 927  GLY 927  886  886  GLY GLY A . n 
A 1 928  GLU 928  887  887  GLU GLU A . n 
A 1 929  ALA 929  888  888  ALA ALA A . n 
A 1 930  ILE 930  889  889  ILE ILE A . n 
A 1 931  ALA 931  890  890  ALA ALA A . n 
A 1 932  ASN 932  891  891  ASN ASN A . n 
A 1 933  VAL 933  892  892  VAL VAL A . n 
A 1 934  ARG 934  893  893  ARG ARG A . n 
A 1 935  THR 935  894  894  THR THR A . n 
A 1 936  VAL 936  895  895  VAL VAL A . n 
A 1 937  ALA 937  896  896  ALA ALA A . n 
A 1 938  ALA 938  897  897  ALA ALA A . n 
A 1 939  PHE 939  898  898  PHE PHE A . n 
A 1 940  ASN 940  899  899  ASN ASN A . n 
A 1 941  SER 941  900  900  SER SER A . n 
A 1 942  GLU 942  901  901  GLU GLU A . n 
A 1 943  ALA 943  902  902  ALA ALA A . n 
A 1 944  LYS 944  903  903  LYS LYS A . n 
A 1 945  ILE 945  904  904  ILE ILE A . n 
A 1 946  VAL 946  905  905  VAL VAL A . n 
A 1 947  ARG 947  906  906  ARG ARG A . n 
A 1 948  LEU 948  907  907  LEU LEU A . n 
A 1 949  TYR 949  908  908  TYR TYR A . n 
A 1 950  THR 950  909  909  THR THR A . n 
A 1 951  ALA 951  910  910  ALA ALA A . n 
A 1 952  ASN 952  911  911  ASN ASN A . n 
A 1 953  LEU 953  912  912  LEU LEU A . n 
A 1 954  GLU 954  913  913  GLU GLU A . n 
A 1 955  PRO 955  914  914  PRO PRO A . n 
A 1 956  PRO 956  915  915  PRO PRO A . n 
A 1 957  LEU 957  916  916  LEU LEU A . n 
A 1 958  LYS 958  917  917  LYS LYS A . n 
A 1 959  ARG 959  918  918  ARG ARG A . n 
A 1 960  CYS 960  919  919  CYS CYS A . n 
A 1 961  PHE 961  920  920  PHE PHE A . n 
A 1 962  TRP 962  921  921  TRP TRP A . n 
A 1 963  LYS 963  922  922  LYS LYS A . n 
A 1 964  GLY 964  923  923  GLY GLY A . n 
A 1 965  GLN 965  924  924  GLN GLN A . n 
A 1 966  ILE 966  925  925  ILE ILE A . n 
A 1 967  ALA 967  926  926  ALA ALA A . n 
A 1 968  GLY 968  927  927  GLY GLY A . n 
A 1 969  SER 969  928  928  SER SER A . n 
A 1 970  GLY 970  929  929  GLY GLY A . n 
A 1 971  TYR 971  930  930  TYR TYR A . n 
A 1 972  GLY 972  931  931  GLY GLY A . n 
A 1 973  VAL 973  932  932  VAL VAL A . n 
A 1 974  ALA 974  933  933  ALA ALA A . n 
A 1 975  GLN 975  934  934  GLN GLN A . n 
A 1 976  PHE 976  935  935  PHE PHE A . n 
A 1 977  CYS 977  936  936  CYS CYS A . n 
A 1 978  LEU 978  937  937  LEU LEU A . n 
A 1 979  TYR 979  938  938  TYR TYR A . n 
A 1 980  ALA 980  939  939  ALA ALA A . n 
A 1 981  SER 981  940  940  SER SER A . n 
A 1 982  TYR 982  941  941  TYR TYR A . n 
A 1 983  ALA 983  942  942  ALA ALA A . n 
A 1 984  LEU 984  943  943  LEU LEU A . n 
A 1 985  GLY 985  944  944  GLY GLY A . n 
A 1 986  LEU 986  945  945  LEU LEU A . n 
A 1 987  TRP 987  946  946  TRP TRP A . n 
A 1 988  TYR 988  947  947  TYR TYR A . n 
A 1 989  ALA 989  948  948  ALA ALA A . n 
A 1 990  SER 990  949  949  SER SER A . n 
A 1 991  TRP 991  950  950  TRP TRP A . n 
A 1 992  LEU 992  951  951  LEU LEU A . n 
A 1 993  VAL 993  952  952  VAL VAL A . n 
A 1 994  LYS 994  953  953  LYS LYS A . n 
A 1 995  HIS 995  954  954  HIS HIS A . n 
A 1 996  GLY 996  955  955  GLY GLY A . n 
A 1 997  ILE 997  956  956  ILE ILE A . n 
A 1 998  SER 998  957  957  SER SER A . n 
A 1 999  ASP 999  958  958  ASP ASP A . n 
A 1 1000 PHE 1000 959  959  PHE PHE A . n 
A 1 1001 SER 1001 960  960  SER SER A . n 
A 1 1002 LYS 1002 961  961  LYS LYS A . n 
A 1 1003 THR 1003 962  962  THR THR A . n 
A 1 1004 ILE 1004 963  963  ILE ILE A . n 
A 1 1005 ARG 1005 964  964  ARG ARG A . n 
A 1 1006 VAL 1006 965  965  VAL VAL A . n 
A 1 1007 PHE 1007 966  966  PHE PHE A . n 
A 1 1008 MET 1008 967  967  MET MET A . n 
A 1 1009 VAL 1009 968  968  VAL VAL A . n 
A 1 1010 LEU 1010 969  969  LEU LEU A . n 
A 1 1011 MET 1011 970  970  MET MET A . n 
A 1 1012 VAL 1012 971  971  VAL VAL A . n 
A 1 1013 SER 1013 972  972  SER SER A . n 
A 1 1014 ALA 1014 973  973  ALA ALA A . n 
A 1 1015 ASN 1015 974  974  ASN ASN A . n 
A 1 1016 GLY 1016 975  975  GLY GLY A . n 
A 1 1017 ALA 1017 976  976  ALA ALA A . n 
A 1 1018 ALA 1018 977  977  ALA ALA A . n 
A 1 1019 GLU 1019 978  978  GLU GLU A . n 
A 1 1020 THR 1020 979  979  THR THR A . n 
A 1 1021 LEU 1021 980  980  LEU LEU A . n 
A 1 1022 THR 1022 981  981  THR THR A . n 
A 1 1023 LEU 1023 982  982  LEU LEU A . n 
A 1 1024 ALA 1024 983  983  ALA ALA A . n 
A 1 1025 PRO 1025 984  984  PRO PRO A . n 
A 1 1026 ASP 1026 985  985  ASP ASP A . n 
A 1 1027 PHE 1027 986  986  PHE PHE A . n 
A 1 1028 ILE 1028 987  987  ILE ILE A . n 
A 1 1029 LYS 1029 988  988  LYS LYS A . n 
A 1 1030 GLY 1030 989  989  GLY GLY A . n 
A 1 1031 GLY 1031 990  990  GLY GLY A . n 
A 1 1032 GLN 1032 991  991  GLN GLN A . n 
A 1 1033 ALA 1033 992  992  ALA ALA A . n 
A 1 1034 MET 1034 993  993  MET MET A . n 
A 1 1035 ARG 1035 994  994  ARG ARG A . n 
A 1 1036 SER 1036 995  995  SER SER A . n 
A 1 1037 VAL 1037 996  996  VAL VAL A . n 
A 1 1038 PHE 1038 997  997  PHE PHE A . n 
A 1 1039 GLU 1039 998  998  GLU GLU A . n 
A 1 1040 LEU 1040 999  999  LEU LEU A . n 
A 1 1041 LEU 1041 1000 1000 LEU LEU A . n 
A 1 1042 ASP 1042 1001 1001 ASP ASP A . n 
A 1 1043 ARG 1043 1002 1002 ARG ARG A . n 
A 1 1044 LYS 1044 1003 1003 LYS LYS A . n 
A 1 1045 THR 1045 1004 1004 THR THR A . n 
A 1 1046 GLU 1046 1005 1005 GLU GLU A . n 
A 1 1047 ILE 1047 1006 1006 ILE ILE A . n 
A 1 1048 GLU 1048 1007 1007 GLU GLU A . n 
A 1 1049 PRO 1049 1008 1008 PRO PRO A . n 
A 1 1050 ASP 1050 1009 1009 ASP ASP A . n 
A 1 1051 ASP 1051 1010 1010 ASP ASP A . n 
A 1 1052 PRO 1052 1011 1011 PRO PRO A . n 
A 1 1053 ASP 1053 1012 1012 ASP ASP A . n 
A 1 1054 THR 1054 1013 1013 THR THR A . n 
A 1 1055 THR 1055 1014 1014 THR THR A . n 
A 1 1056 PRO 1056 1015 1015 PRO PRO A . n 
A 1 1057 VAL 1057 1016 1016 VAL VAL A . n 
A 1 1058 PRO 1058 1017 1017 PRO PRO A . n 
A 1 1059 ASP 1059 1018 1018 ASP ASP A . n 
A 1 1060 ARG 1060 1019 1019 ARG ARG A . n 
A 1 1061 LEU 1061 1020 1020 LEU LEU A . n 
A 1 1062 ARG 1062 1021 1021 ARG ARG A . n 
A 1 1063 GLY 1063 1022 1022 GLY GLY A . n 
A 1 1064 GLU 1064 1023 1023 GLU GLU A . n 
A 1 1065 VAL 1065 1024 1024 VAL VAL A . n 
A 1 1066 GLU 1066 1025 1025 GLU GLU A . n 
A 1 1067 LEU 1067 1026 1026 LEU LEU A . n 
A 1 1068 LYS 1068 1027 1027 LYS LYS A . n 
A 1 1069 HIS 1069 1028 1028 HIS HIS A . n 
A 1 1070 ILE 1070 1029 1029 ILE ILE A . n 
A 1 1071 ASP 1071 1030 1030 ASP ASP A . n 
A 1 1072 PHE 1072 1031 1031 PHE PHE A . n 
A 1 1073 SER 1073 1032 1032 SER SER A . n 
A 1 1074 TYR 1074 1033 1033 TYR TYR A . n 
A 1 1075 PRO 1075 1034 1034 PRO PRO A . n 
A 1 1076 SER 1076 1035 1035 SER SER A . n 
A 1 1077 ARG 1077 1036 1036 ARG ARG A . n 
A 1 1078 PRO 1078 1037 1037 PRO PRO A . n 
A 1 1079 ASP 1079 1038 1038 ASP ASP A . n 
A 1 1080 ILE 1080 1039 1039 ILE ILE A . n 
A 1 1081 GLN 1081 1040 1040 GLN GLN A . n 
A 1 1082 ILE 1082 1041 1041 ILE ILE A . n 
A 1 1083 PHE 1083 1042 1042 PHE PHE A . n 
A 1 1084 ARG 1084 1043 1043 ARG ARG A . n 
A 1 1085 ASP 1085 1044 1044 ASP ASP A . n 
A 1 1086 LEU 1086 1045 1045 LEU LEU A . n 
A 1 1087 SER 1087 1046 1046 SER SER A . n 
A 1 1088 LEU 1088 1047 1047 LEU LEU A . n 
A 1 1089 ARG 1089 1048 1048 ARG ARG A . n 
A 1 1090 ALA 1090 1049 1049 ALA ALA A . n 
A 1 1091 ARG 1091 1050 1050 ARG ARG A . n 
A 1 1092 ALA 1092 1051 1051 ALA ALA A . n 
A 1 1093 GLY 1093 1052 1052 GLY GLY A . n 
A 1 1094 LYS 1094 1053 1053 LYS LYS A . n 
A 1 1095 THR 1095 1054 1054 THR THR A . n 
A 1 1096 LEU 1096 1055 1055 LEU LEU A . n 
A 1 1097 ALA 1097 1056 1056 ALA ALA A . n 
A 1 1098 LEU 1098 1057 1057 LEU LEU A . n 
A 1 1099 VAL 1099 1058 1058 VAL VAL A . n 
A 1 1100 GLY 1100 1059 1059 GLY GLY A . n 
A 1 1101 PRO 1101 1060 1060 PRO PRO A . n 
A 1 1102 SER 1102 1061 1061 SER SER A . n 
A 1 1103 GLY 1103 1062 1062 GLY GLY A . n 
A 1 1104 CYS 1104 1063 1063 CYS CYS A . n 
A 1 1105 GLY 1105 1064 1064 GLY GLY A . n 
A 1 1106 LYS 1106 1065 1065 LYS LYS A . n 
A 1 1107 SER 1107 1066 1066 SER SER A . n 
A 1 1108 SER 1108 1067 1067 SER SER A . n 
A 1 1109 VAL 1109 1068 1068 VAL VAL A . n 
A 1 1110 ILE 1110 1069 1069 ILE ILE A . n 
A 1 1111 SER 1111 1070 1070 SER SER A . n 
A 1 1112 LEU 1112 1071 1071 LEU LEU A . n 
A 1 1113 ILE 1113 1072 1072 ILE ILE A . n 
A 1 1114 GLN 1114 1073 1073 GLN GLN A . n 
A 1 1115 ARG 1115 1074 1074 ARG ARG A . n 
A 1 1116 PHE 1116 1075 1075 PHE PHE A . n 
A 1 1117 TYR 1117 1076 1076 TYR TYR A . n 
A 1 1118 GLU 1118 1077 1077 GLU GLU A . n 
A 1 1119 PRO 1119 1078 1078 PRO PRO A . n 
A 1 1120 SER 1120 1079 1079 SER SER A . n 
A 1 1121 SER 1121 1080 1080 SER SER A . n 
A 1 1122 GLY 1122 1081 1081 GLY GLY A . n 
A 1 1123 ARG 1123 1082 1082 ARG ARG A . n 
A 1 1124 VAL 1124 1083 1083 VAL VAL A . n 
A 1 1125 MET 1125 1084 1084 MET MET A . n 
A 1 1126 ILE 1126 1085 1085 ILE ILE A . n 
A 1 1127 ASP 1127 1086 1086 ASP ASP A . n 
A 1 1128 GLY 1128 1087 1087 GLY GLY A . n 
A 1 1129 LYS 1129 1088 1088 LYS LYS A . n 
A 1 1130 ASP 1130 1089 1089 ASP ASP A . n 
A 1 1131 ILE 1131 1090 1090 ILE ILE A . n 
A 1 1132 ARG 1132 1091 1091 ARG ARG A . n 
A 1 1133 LYS 1133 1092 1092 LYS LYS A . n 
A 1 1134 TYR 1134 1093 1093 TYR TYR A . n 
A 1 1135 ASN 1135 1094 1094 ASN ASN A . n 
A 1 1136 LEU 1136 1095 1095 LEU LEU A . n 
A 1 1137 LYS 1137 1096 1096 LYS LYS A . n 
A 1 1138 ALA 1138 1097 1097 ALA ALA A . n 
A 1 1139 ILE 1139 1098 1098 ILE ILE A . n 
A 1 1140 ARG 1140 1099 1099 ARG ARG A . n 
A 1 1141 LYS 1141 1100 1100 LYS LYS A . n 
A 1 1142 HIS 1142 1101 1101 HIS HIS A . n 
A 1 1143 ILE 1143 1102 1102 ILE ILE A . n 
A 1 1144 ALA 1144 1103 1103 ALA ALA A . n 
A 1 1145 ILE 1145 1104 1104 ILE ILE A . n 
A 1 1146 VAL 1146 1105 1105 VAL VAL A . n 
A 1 1147 PRO 1147 1106 1106 PRO PRO A . n 
A 1 1148 GLN 1148 1107 1107 GLN GLN A . n 
A 1 1149 GLU 1149 1108 1108 GLU GLU A . n 
A 1 1150 PRO 1150 1109 1109 PRO PRO A . n 
A 1 1151 CYS 1151 1110 1110 CYS CYS A . n 
A 1 1152 LEU 1152 1111 1111 LEU LEU A . n 
A 1 1153 PHE 1153 1112 1112 PHE PHE A . n 
A 1 1154 GLY 1154 1113 1113 GLY GLY A . n 
A 1 1155 THR 1155 1114 1114 THR THR A . n 
A 1 1156 THR 1156 1115 1115 THR THR A . n 
A 1 1157 ILE 1157 1116 1116 ILE ILE A . n 
A 1 1158 TYR 1158 1117 1117 TYR TYR A . n 
A 1 1159 GLU 1159 1118 1118 GLU GLU A . n 
A 1 1160 ASN 1160 1119 1119 ASN ASN A . n 
A 1 1161 ILE 1161 1120 1120 ILE ILE A . n 
A 1 1162 ALA 1162 1121 1121 ALA ALA A . n 
A 1 1163 TYR 1163 1122 1122 TYR TYR A . n 
A 1 1164 GLY 1164 1123 1123 GLY GLY A . n 
A 1 1165 HIS 1165 1124 1124 HIS HIS A . n 
A 1 1166 GLU 1166 1125 1125 GLU GLU A . n 
A 1 1167 CYS 1167 1126 1126 CYS CYS A . n 
A 1 1168 ALA 1168 1127 1127 ALA ALA A . n 
A 1 1169 THR 1169 1128 1128 THR THR A . n 
A 1 1170 GLU 1170 1129 1129 GLU GLU A . n 
A 1 1171 ALA 1171 1130 1130 ALA ALA A . n 
A 1 1172 GLU 1172 1131 1131 GLU GLU A . n 
A 1 1173 ILE 1173 1132 1132 ILE ILE A . n 
A 1 1174 ILE 1174 1133 1133 ILE ILE A . n 
A 1 1175 GLN 1175 1134 1134 GLN GLN A . n 
A 1 1176 ALA 1176 1135 1135 ALA ALA A . n 
A 1 1177 ALA 1177 1136 1136 ALA ALA A . n 
A 1 1178 THR 1178 1137 1137 THR THR A . n 
A 1 1179 LEU 1179 1138 1138 LEU LEU A . n 
A 1 1180 ALA 1180 1139 1139 ALA ALA A . n 
A 1 1181 SER 1181 1140 1140 SER SER A . n 
A 1 1182 ALA 1182 1141 1141 ALA ALA A . n 
A 1 1183 HIS 1183 1142 1142 HIS HIS A . n 
A 1 1184 LYS 1184 1143 1143 LYS LYS A . n 
A 1 1185 PHE 1185 1144 1144 PHE PHE A . n 
A 1 1186 ILE 1186 1145 1145 ILE ILE A . n 
A 1 1187 SER 1187 1146 1146 SER SER A . n 
A 1 1188 ALA 1188 1147 1147 ALA ALA A . n 
A 1 1189 LEU 1189 1148 1148 LEU LEU A . n 
A 1 1190 PRO 1190 1149 1149 PRO PRO A . n 
A 1 1191 GLU 1191 1150 1150 GLU GLU A . n 
A 1 1192 GLY 1192 1151 1151 GLY GLY A . n 
A 1 1193 TYR 1193 1152 1152 TYR TYR A . n 
A 1 1194 LYS 1194 1153 1153 LYS LYS A . n 
A 1 1195 THR 1195 1154 1154 THR THR A . n 
A 1 1196 TYR 1196 1155 1155 TYR TYR A . n 
A 1 1197 VAL 1197 1156 1156 VAL VAL A . n 
A 1 1198 GLY 1198 1157 1157 GLY GLY A . n 
A 1 1199 GLU 1199 1158 1158 GLU GLU A . n 
A 1 1200 ARG 1200 1159 1159 ARG ARG A . n 
A 1 1201 GLY 1201 1160 1160 GLY GLY A . n 
A 1 1202 VAL 1202 1161 1161 VAL VAL A . n 
A 1 1203 GLN 1203 1162 1162 GLN GLN A . n 
A 1 1204 LEU 1204 1163 1163 LEU LEU A . n 
A 1 1205 SER 1205 1164 1164 SER SER A . n 
A 1 1206 GLY 1206 1165 1165 GLY GLY A . n 
A 1 1207 GLY 1207 1166 1166 GLY GLY A . n 
A 1 1208 GLN 1208 1167 1167 GLN GLN A . n 
A 1 1209 LYS 1209 1168 1168 LYS LYS A . n 
A 1 1210 GLN 1210 1169 1169 GLN GLN A . n 
A 1 1211 ARG 1211 1170 1170 ARG ARG A . n 
A 1 1212 ILE 1212 1171 1171 ILE ILE A . n 
A 1 1213 ALA 1213 1172 1172 ALA ALA A . n 
A 1 1214 ILE 1214 1173 1173 ILE ILE A . n 
A 1 1215 ALA 1215 1174 1174 ALA ALA A . n 
A 1 1216 ARG 1216 1175 1175 ARG ARG A . n 
A 1 1217 ALA 1217 1176 1176 ALA ALA A . n 
A 1 1218 LEU 1218 1177 1177 LEU LEU A . n 
A 1 1219 VAL 1219 1178 1178 VAL VAL A . n 
A 1 1220 ARG 1220 1179 1179 ARG ARG A . n 
A 1 1221 LYS 1221 1180 1180 LYS LYS A . n 
A 1 1222 ALA 1222 1181 1181 ALA ALA A . n 
A 1 1223 GLU 1223 1182 1182 GLU GLU A . n 
A 1 1224 ILE 1224 1183 1183 ILE ILE A . n 
A 1 1225 MET 1225 1184 1184 MET MET A . n 
A 1 1226 LEU 1226 1185 1185 LEU LEU A . n 
A 1 1227 LEU 1227 1186 1186 LEU LEU A . n 
A 1 1228 ASP 1228 1187 1187 ASP ASP A . n 
A 1 1229 GLU 1229 1188 1188 GLU GLU A . n 
A 1 1230 ALA 1230 1189 1189 ALA ALA A . n 
A 1 1231 THR 1231 1190 1190 THR THR A . n 
A 1 1232 SER 1232 1191 1191 SER SER A . n 
A 1 1233 ALA 1233 1192 1192 ALA ALA A . n 
A 1 1234 LEU 1234 1193 1193 LEU LEU A . n 
A 1 1235 ASP 1235 1194 1194 ASP ASP A . n 
A 1 1236 ALA 1236 1195 1195 ALA ALA A . n 
A 1 1237 GLU 1237 1196 1196 GLU GLU A . n 
A 1 1238 SER 1238 1197 1197 SER SER A . n 
A 1 1239 GLU 1239 1198 1198 GLU GLU A . n 
A 1 1240 ARG 1240 1199 1199 ARG ARG A . n 
A 1 1241 SER 1241 1200 1200 SER SER A . n 
A 1 1242 VAL 1242 1201 1201 VAL VAL A . n 
A 1 1243 GLN 1243 1202 1202 GLN GLN A . n 
A 1 1244 GLU 1244 1203 1203 GLU GLU A . n 
A 1 1245 ALA 1245 1204 1204 ALA ALA A . n 
A 1 1246 LEU 1246 1205 1205 LEU LEU A . n 
A 1 1247 ASP 1247 1206 1206 ASP ASP A . n 
A 1 1248 GLN 1248 1207 1207 GLN GLN A . n 
A 1 1249 ALA 1249 1208 1208 ALA ALA A . n 
A 1 1250 CYS 1250 1209 1209 CYS CYS A . n 
A 1 1251 SER 1251 1210 1210 SER SER A . n 
A 1 1252 GLY 1252 1211 1211 GLY GLY A . n 
A 1 1253 ARG 1253 1212 1212 ARG ARG A . n 
A 1 1254 THR 1254 1213 1213 THR THR A . n 
A 1 1255 SER 1255 1214 1214 SER SER A . n 
A 1 1256 ILE 1256 1215 1215 ILE ILE A . n 
A 1 1257 VAL 1257 1216 1216 VAL VAL A . n 
A 1 1258 VAL 1258 1217 1217 VAL VAL A . n 
A 1 1259 ALA 1259 1218 1218 ALA ALA A . n 
A 1 1260 HIS 1260 1219 1219 HIS HIS A . n 
A 1 1261 ARG 1261 1220 1220 ARG ARG A . n 
A 1 1262 LEU 1262 1221 1221 LEU LEU A . n 
A 1 1263 SER 1263 1222 1222 SER SER A . n 
A 1 1264 THR 1264 1223 1223 THR THR A . n 
A 1 1265 ILE 1265 1224 1224 ILE ILE A . n 
A 1 1266 ARG 1266 1225 1225 ARG ARG A . n 
A 1 1267 ASN 1267 1226 1226 ASN ASN A . n 
A 1 1268 ALA 1268 1227 1227 ALA ALA A . n 
A 1 1269 HIS 1269 1228 1228 HIS HIS A . n 
A 1 1270 VAL 1270 1229 1229 VAL VAL A . n 
A 1 1271 ILE 1271 1230 1230 ILE ILE A . n 
A 1 1272 ALA 1272 1231 1231 ALA ALA A . n 
A 1 1273 VAL 1273 1232 1232 VAL VAL A . n 
A 1 1274 ILE 1274 1233 1233 ILE ILE A . n 
A 1 1275 ASP 1275 1234 1234 ASP ASP A . n 
A 1 1276 ASP 1276 1235 1235 ASP ASP A . n 
A 1 1277 GLY 1277 1236 1236 GLY GLY A . n 
A 1 1278 LYS 1278 1237 1237 LYS LYS A . n 
A 1 1279 VAL 1279 1238 1238 VAL VAL A . n 
A 1 1280 ALA 1280 1239 1239 ALA ALA A . n 
A 1 1281 GLU 1281 1240 1240 GLU GLU A . n 
A 1 1282 GLN 1282 1241 1241 GLN GLN A . n 
A 1 1283 GLY 1283 1242 1242 GLY GLY A . n 
A 1 1284 SER 1284 1243 1243 SER SER A . n 
A 1 1285 HIS 1285 1244 1244 HIS HIS A . n 
A 1 1286 SER 1286 1245 1245 SER SER A . n 
A 1 1287 HIS 1287 1246 1246 HIS HIS A . n 
A 1 1288 LEU 1288 1247 1247 LEU LEU A . n 
A 1 1289 LEU 1289 1248 1248 LEU LEU A . n 
A 1 1290 LYS 1290 1249 1249 LYS LYS A . n 
A 1 1291 ASN 1291 1250 1250 ASN ASN A . n 
A 1 1292 HIS 1292 1251 1251 HIS HIS A . n 
A 1 1293 PRO 1293 1252 1252 PRO PRO A . n 
A 1 1294 ASP 1294 1253 1253 ASP ASP A . n 
A 1 1295 GLY 1295 1254 1254 GLY GLY A . n 
A 1 1296 ILE 1296 1255 1255 ILE ILE A . n 
A 1 1297 TYR 1297 1256 1256 TYR TYR A . n 
A 1 1298 ALA 1298 1257 1257 ALA ALA A . n 
A 1 1299 ARG 1299 1258 1258 ARG ARG A . n 
A 1 1300 MET 1300 1259 1259 MET MET A . n 
A 1 1301 ILE 1301 1260 1260 ILE ILE A . n 
A 1 1302 GLN 1302 1261 1261 GLN GLN A . n 
A 1 1303 LEU 1303 1262 1262 LEU LEU A . n 
A 1 1304 GLN 1304 1263 1263 GLN GLN A . n 
A 1 1305 ARG 1305 1264 1264 ARG ARG A . n 
A 1 1306 PHE 1306 1265 ?    ?   ?   A . n 
A 1 1307 THR 1307 1266 ?    ?   ?   A . n 
A 1 1308 HIS 1308 1267 ?    ?   ?   A . n 
A 1 1309 THR 1309 1268 ?    ?   ?   A . n 
A 1 1310 GLN 1310 1269 ?    ?   ?   A . n 
A 1 1311 VAL 1311 1270 ?    ?   ?   A . n 
A 1 1312 ILE 1312 1271 ?    ?   ?   A . n 
A 1 1313 GLY 1313 1272 ?    ?   ?   A . n 
A 1 1314 MET 1314 1273 ?    ?   ?   A . n 
A 1 1315 THR 1315 1274 ?    ?   ?   A . n 
A 1 1316 SER 1316 1275 ?    ?   ?   A . n 
A 1 1317 GLY 1317 1276 ?    ?   ?   A . n 
A 1 1318 SER 1318 1277 ?    ?   ?   A . n 
A 1 1319 SER 1319 1278 ?    ?   ?   A . n 
A 1 1320 SER 1320 1279 ?    ?   ?   A . n 
A 1 1321 ARG 1321 1280 ?    ?   ?   A . n 
A 1 1322 VAL 1322 1281 ?    ?   ?   A . n 
A 1 1323 LYS 1323 1282 ?    ?   ?   A . n 
A 1 1324 GLU 1324 1283 ?    ?   ?   A . n 
A 1 1325 ASP 1325 1284 ?    ?   ?   A . n 
A 1 1326 ASP 1326 1285 ?    ?   ?   A . n 
A 1 1327 ALA 1327 1286 ?    ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        BLD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   BLD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          BLD 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     1301 
_pdbx_nonpoly_scheme.auth_seq_num    1306 
_pdbx_nonpoly_scheme.pdb_mon_id      BLD 
_pdbx_nonpoly_scheme.auth_mon_id     BLD 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JUL 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JUL 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JUL 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9JUL 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.10 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 9174  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.596 ? 12425 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.186 ? 1256  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 1442  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 1572  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9JUL 
_struct.title                        
'Structure of Arabidopsis thaliana ABCB1 with brassinolide bound in the inward-facing conformation' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JUL 
_struct_keywords.text            'ABCB1, auxin transport, brassinolide (BL) transport, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    AB1B_ARATH 
_struct_ref.pdbx_db_accession          Q9ZR72 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MDNDGGAPPPPPTLVVEEPKKAEIRGVAFKELFRFADGLDYVLMGIGSVGAFVHGCSLPLFLRFFADLVNSFGSNSNNVE
KMMEEVLKYALYFLVVGAAIWASSWAEISCWMWSGERQTTKMRIKYLEAALNQDIQFFDTEVRTSDVVFAINTDAVMVQD
AISEKLGNFIHYMATFVSGFIVGFTAVWQLALVTLAVVPLIAVIGGIHTTTLSKLSNKSQESLSQAGNIVEQTVVQIRVV
MAFVGESRASQAYSSALKIAQKLGYKTGLAKGMGLGATYFVVFCCYALLLWYGGYLVRHHLTNGGLAIATMFAVMIGGLA
LGQSAPSMAAFAKAKVAAAKIFRIIDHKPTIERNSESGVELDSVTGLVELKNVDFSYPSRPDVKILNNFCLSVPAGKTIA
LVGSSGSGKSTVVSLIERFYDPNSGQVLLDGQDLKTLKLRWLRQQIGLVSQEPALFATSIKENILLGRPDADQVEIEEAA
RVANAHSFIIKLPDGFDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDRFMIGRTTLI
IAHRLSTIRKADLVAVLQQGSVSEIGTHDELFSKGENGVYAKLIKMQEAAHETAMSNARKSSARPSSARNSVSSPIMTRN
SSYGRSPYSRRLSDFSTSDFSLSIDASSYPNYRNEKLAFKDQANSFWRLAKMNSPEWKYALLGSVGSVICGSLSAFFAYV
LSAVLSVYYNPDHEYMIKQIDKYCYLLIGLSSAALVFNTLQHSFWDIVGENLTKRVREKMLSAVLKNEMAWFDQEENESA
RIAARLALDANNVRSAIGDRISVIVQNTALMLVACTAGFVLQWRLALVLVAVFPVVVAATVLQKMFMTGFSGDLEAAHAK
GTQLAGEAIANVRTVAAFNSEAKIVRLYTANLEPPLKRCFWKGQIAGSGYGVAQFCLYASYALGLWYASWLVKHGISDFS
KTIRVFMVLMVSANGAAETLTLAPDFIKGGQAMRSVFELLDRKTEIEPDDPDTTPVPDRLRGEVELKHIDFSYPSRPDIQ
IFRDLSLRARAGKTLALVGPSGCGKSSVISLIQRFYEPSSGRVMIDGKDIRKYNLKAIRKHIAIVPQEPCLFGTTIYENI
AYGHECATEAEIIQAATLASAHKFISALPEGYKTYVGERGVQLSGGQKQRIAIARALVRKAEIMLLDEATSALDAESERS
VQEALDQACSGRTSIVVAHRLSTIRNAHVIAVIDDGKVAEQGSHSHLLKNHPDGIYARMIQLQRFTHTQVIGMTSGSSSR
VKEDDA
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9JUL 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 42 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1327 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q9ZR72 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1286 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       1286 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9JUL MET A 1  ? UNP Q9ZR72 ? ? 'initiating methionine' -40 1  
1 9JUL ASP A 2  ? UNP Q9ZR72 ? ? 'expression tag'        -39 2  
1 9JUL TYR A 3  ? UNP Q9ZR72 ? ? 'expression tag'        -38 3  
1 9JUL LYS A 4  ? UNP Q9ZR72 ? ? 'expression tag'        -37 4  
1 9JUL ASP A 5  ? UNP Q9ZR72 ? ? 'expression tag'        -36 5  
1 9JUL ASP A 6  ? UNP Q9ZR72 ? ? 'expression tag'        -35 6  
1 9JUL ASP A 7  ? UNP Q9ZR72 ? ? 'expression tag'        -34 7  
1 9JUL ASP A 8  ? UNP Q9ZR72 ? ? 'expression tag'        -33 8  
1 9JUL LYS A 9  ? UNP Q9ZR72 ? ? 'expression tag'        -32 9  
1 9JUL TRP A 10 ? UNP Q9ZR72 ? ? 'expression tag'        -31 10 
1 9JUL SER A 11 ? UNP Q9ZR72 ? ? 'expression tag'        -30 11 
1 9JUL HIS A 12 ? UNP Q9ZR72 ? ? 'expression tag'        -29 12 
1 9JUL PRO A 13 ? UNP Q9ZR72 ? ? 'expression tag'        -28 13 
1 9JUL GLN A 14 ? UNP Q9ZR72 ? ? 'expression tag'        -27 14 
1 9JUL PHE A 15 ? UNP Q9ZR72 ? ? 'expression tag'        -26 15 
1 9JUL GLU A 16 ? UNP Q9ZR72 ? ? 'expression tag'        -25 16 
1 9JUL LYS A 17 ? UNP Q9ZR72 ? ? 'expression tag'        -24 17 
1 9JUL GLY A 18 ? UNP Q9ZR72 ? ? 'expression tag'        -23 18 
1 9JUL GLY A 19 ? UNP Q9ZR72 ? ? 'expression tag'        -22 19 
1 9JUL GLY A 20 ? UNP Q9ZR72 ? ? 'expression tag'        -21 20 
1 9JUL GLY A 21 ? UNP Q9ZR72 ? ? 'expression tag'        -20 21 
1 9JUL SER A 22 ? UNP Q9ZR72 ? ? 'expression tag'        -19 22 
1 9JUL GLY A 23 ? UNP Q9ZR72 ? ? 'expression tag'        -18 23 
1 9JUL GLY A 24 ? UNP Q9ZR72 ? ? 'expression tag'        -17 24 
1 9JUL SER A 25 ? UNP Q9ZR72 ? ? 'expression tag'        -16 25 
1 9JUL ALA A 26 ? UNP Q9ZR72 ? ? 'expression tag'        -15 26 
1 9JUL TRP A 27 ? UNP Q9ZR72 ? ? 'expression tag'        -14 27 
1 9JUL SER A 28 ? UNP Q9ZR72 ? ? 'expression tag'        -13 28 
1 9JUL HIS A 29 ? UNP Q9ZR72 ? ? 'expression tag'        -12 29 
1 9JUL PRO A 30 ? UNP Q9ZR72 ? ? 'expression tag'        -11 30 
1 9JUL GLN A 31 ? UNP Q9ZR72 ? ? 'expression tag'        -10 31 
1 9JUL PHE A 32 ? UNP Q9ZR72 ? ? 'expression tag'        -9  32 
1 9JUL GLU A 33 ? UNP Q9ZR72 ? ? 'expression tag'        -8  33 
1 9JUL LYS A 34 ? UNP Q9ZR72 ? ? 'expression tag'        -7  34 
1 9JUL GLU A 35 ? UNP Q9ZR72 ? ? 'expression tag'        -6  35 
1 9JUL PHE A 36 ? UNP Q9ZR72 ? ? 'expression tag'        -5  36 
1 9JUL LYS A 37 ? UNP Q9ZR72 ? ? 'expression tag'        -4  37 
1 9JUL GLY A 38 ? UNP Q9ZR72 ? ? 'expression tag'        -3  38 
1 9JUL LEU A 39 ? UNP Q9ZR72 ? ? 'expression tag'        -2  39 
1 9JUL VAL A 40 ? UNP Q9ZR72 ? ? 'expression tag'        -1  40 
1 9JUL ASP A 41 ? UNP Q9ZR72 ? ? 'expression tag'        0   41 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 69   ? ARG A 75   ? ALA A 28   ARG A 34   5 ? 7  
HELX_P HELX_P2  AA2 ASP A 78   ? ASN A 116  ? ASP A 37   ASN A 75   1 ? 39 
HELX_P HELX_P3  AA3 ASN A 119  ? ASN A 173  ? ASN A 78   ASN A 132  1 ? 55 
HELX_P HELX_P4  AA4 ASP A 175  ? GLU A 182  ? ASP A 134  GLU A 141  1 ? 8  
HELX_P HELX_P5  AA5 ARG A 184  ? GLU A 205  ? ARG A 143  GLU A 164  1 ? 22 
HELX_P HELX_P6  AA6 GLU A 205  ? VAL A 228  ? GLU A 164  VAL A 187  1 ? 24 
HELX_P HELX_P7  AA7 VAL A 228  ? GLN A 277  ? VAL A 187  GLN A 236  1 ? 50 
HELX_P HELX_P8  AA8 GLN A 277  ? PHE A 284  ? GLN A 236  PHE A 243  1 ? 8  
HELX_P HELX_P9  AA9 GLY A 286  ? HIS A 340  ? GLY A 245  HIS A 299  1 ? 55 
HELX_P HELX_P10 AB1 ASN A 344  ? HIS A 388  ? ASN A 303  HIS A 347  1 ? 45 
HELX_P HELX_P11 AB2 GLY A 449  ? GLU A 458  ? GLY A 408  GLU A 417  1 ? 10 
HELX_P HELX_P12 AB3 LEU A 475  ? LYS A 479  ? LEU A 434  LYS A 438  5 ? 5  
HELX_P HELX_P13 AB4 TRP A 482  ? ILE A 487  ? TRP A 441  ILE A 446  1 ? 6  
HELX_P HELX_P14 AB5 SER A 500  ? LEU A 507  ? SER A 459  LEU A 466  1 ? 8  
HELX_P HELX_P15 AB6 ASP A 513  ? ALA A 524  ? ASP A 472  ALA A 483  1 ? 12 
HELX_P HELX_P16 AB7 GLY A 550  ? LEU A 563  ? GLY A 509  LEU A 522  1 ? 14 
HELX_P HELX_P17 AB8 ASP A 579  ? PHE A 593  ? ASP A 538  PHE A 552  1 ? 15 
HELX_P HELX_P18 AB9 ARG A 605  ? ALA A 612  ? ARG A 564  ALA A 571  1 ? 8  
HELX_P HELX_P19 AC1 LEU A 618  ? SER A 622  ? LEU A 577  SER A 581  5 ? 5  
HELX_P HELX_P20 AC2 PHE A 720  ? ASN A 734  ? PHE A 679  ASN A 693  1 ? 15 
HELX_P HELX_P21 AC3 GLU A 737  ? TYR A 770  ? GLU A 696  TYR A 729  1 ? 34 
HELX_P HELX_P22 AC4 ASP A 773  ? ASN A 828  ? ASP A 732  ASN A 787  1 ? 56 
HELX_P HELX_P23 AC5 GLU A 829  ? GLN A 835  ? GLU A 788  GLN A 794  1 ? 7  
HELX_P HELX_P24 AC6 SER A 840  ? VAL A 893  ? SER A 799  VAL A 852  1 ? 54 
HELX_P HELX_P25 AC7 VAL A 893  ? GLY A 910  ? VAL A 852  GLY A 869  1 ? 18 
HELX_P HELX_P26 AC8 ASP A 914  ? HIS A 919  ? ASP A 873  HIS A 878  1 ? 6  
HELX_P HELX_P27 AC9 HIS A 919  ? ASN A 932  ? HIS A 878  ASN A 891  1 ? 14 
HELX_P HELX_P28 AD1 ASN A 932  ? PHE A 939  ? ASN A 891  PHE A 898  1 ? 8  
HELX_P HELX_P29 AD2 SER A 941  ? HIS A 995  ? SER A 900  HIS A 954  1 ? 55 
HELX_P HELX_P30 AD3 ASP A 999  ? THR A 1022 ? ASP A 958  THR A 981  1 ? 24 
HELX_P HELX_P31 AD4 ASP A 1026 ? ASP A 1042 ? ASP A 985  ASP A 1001 1 ? 17 
HELX_P HELX_P32 AD5 GLY A 1105 ? GLN A 1114 ? GLY A 1064 GLN A 1073 1 ? 10 
HELX_P HELX_P33 AD6 ASN A 1135 ? LYS A 1141 ? ASN A 1094 LYS A 1100 1 ? 7  
HELX_P HELX_P34 AD7 THR A 1156 ? TYR A 1163 ? THR A 1115 TYR A 1122 1 ? 8  
HELX_P HELX_P35 AD8 GLU A 1170 ? ALA A 1180 ? GLU A 1129 ALA A 1139 1 ? 11 
HELX_P HELX_P36 AD9 ALA A 1182 ? LEU A 1189 ? ALA A 1141 LEU A 1148 1 ? 8  
HELX_P HELX_P37 AE1 GLU A 1191 ? THR A 1195 ? GLU A 1150 THR A 1154 5 ? 5  
HELX_P HELX_P38 AE2 SER A 1205 ? ARG A 1220 ? SER A 1164 ARG A 1179 1 ? 16 
HELX_P HELX_P39 AE3 ASP A 1235 ? SER A 1251 ? ASP A 1194 SER A 1210 1 ? 17 
HELX_P HELX_P40 AE4 ASP A 1275 ? LYS A 1278 ? ASP A 1234 LYS A 1237 5 ? 4  
HELX_P HELX_P41 AE5 SER A 1284 ? ASN A 1291 ? SER A 1243 ASN A 1250 1 ? 8  
HELX_P HELX_P42 AE6 GLY A 1295 ? ARG A 1305 ? GLY A 1254 ARG A 1264 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 4 ? 
AA3 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 488  ? LEU A 489  ? GLY A 447  LEU A 448  
AA1 2 LEU A 569  ? LEU A 570  ? LEU A 528  LEU A 529  
AA2 1 PHE A 1083 ? ARG A 1089 ? PHE A 1042 ARG A 1048 
AA2 2 VAL A 1065 ? PHE A 1072 ? VAL A 1024 PHE A 1031 
AA2 3 MET A 1125 ? ILE A 1126 ? MET A 1084 ILE A 1085 
AA2 4 LYS A 1129 ? ASP A 1130 ? LYS A 1088 ASP A 1089 
AA3 1 ILE A 1143 ? ILE A 1145 ? ILE A 1102 ILE A 1104 
AA3 2 ILE A 1224 ? LEU A 1227 ? ILE A 1183 LEU A 1186 
AA3 3 THR A 1254 ? VAL A 1258 ? THR A 1213 VAL A 1217 
AA3 4 THR A 1095 ? VAL A 1099 ? THR A 1054 VAL A 1058 
AA3 5 VAL A 1270 ? VAL A 1273 ? VAL A 1229 VAL A 1232 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 488  ? N GLY A 447  O LEU A 570  ? O LEU A 529  
AA2 1 2 O PHE A 1083 ? O PHE A 1042 N PHE A 1072 ? N PHE A 1031 
AA2 2 3 N GLU A 1066 ? N GLU A 1025 O MET A 1125 ? O MET A 1084 
AA2 3 4 N ILE A 1126 ? N ILE A 1085 O LYS A 1129 ? O LYS A 1088 
AA3 1 2 N ALA A 1144 ? N ALA A 1103 O LEU A 1226 ? O LEU A 1185 
AA3 2 3 N MET A 1225 ? N MET A 1184 O ILE A 1256 ? O ILE A 1215 
AA3 3 4 O VAL A 1257 ? O VAL A 1216 N LEU A 1098 ? N LEU A 1057 
AA3 4 5 N ALA A 1097 ? N ALA A 1056 O VAL A 1270 ? O VAL A 1229 
# 
_pdbx_entry_details.entry_id                   9JUL 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN A 75   ? ? -93.79  33.74   
2  1 VAL A 156  ? ? -105.42 -65.90  
3  1 PHE A 243  ? ? -95.60  -133.34 
4  1 LEU A 370  ? ? 60.01   65.29   
5  1 ILE A 385  ? ? -109.05 -61.20  
6  1 SER A 392  ? ? 67.13   149.50  
7  1 SER A 404  ? ? 38.10   -131.28 
8  1 ASN A 423  ? ? -69.62  -176.40 
9  1 ASP A 433  ? ? 61.21   -171.87 
10 1 LYS A 438  ? ? 57.80   -175.25 
11 1 ASP A 497  ? ? -97.21  35.65   
12 1 ALA A 526  ? ? 66.15   -164.38 
13 1 PHE A 552  ? ? -100.81 75.20   
14 1 ILE A 561  ? ? 37.71   58.01   
15 1 GLN A 579  ? ? 38.91   42.72   
16 1 TYR A 729  ? ? -95.56  58.97   
17 1 ASN A 797  ? ? -141.07 33.27   
18 1 SER A 799  ? ? 65.27   -138.50 
19 1 ILE A 817  ? ? -96.04  -66.71  
20 1 ASN A 899  ? ? 34.75   54.01   
21 1 ALA A 983  ? ? -47.49  108.53  
22 1 PRO A 984  ? ? -91.53  55.52   
23 1 THR A 1128 ? ? 51.67   -137.81 
24 1 LYS A 1180 ? ? 38.13   49.47   
25 1 ARG A 1212 ? ? 58.26   -154.41 
26 1 HIS A 1251 ? ? 38.65   70.79   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JUL 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9JUL 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               197075 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Structure of Arabidopsis thaliana ABCB1 with brassinolide bound in the inward-facing conformation' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9JUL 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9JUL 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9JUL 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -40  ? A MET 1    
2   1 Y 1 A ASP -39  ? A ASP 2    
3   1 Y 1 A TYR -38  ? A TYR 3    
4   1 Y 1 A LYS -37  ? A LYS 4    
5   1 Y 1 A ASP -36  ? A ASP 5    
6   1 Y 1 A ASP -35  ? A ASP 6    
7   1 Y 1 A ASP -34  ? A ASP 7    
8   1 Y 1 A ASP -33  ? A ASP 8    
9   1 Y 1 A LYS -32  ? A LYS 9    
10  1 Y 1 A TRP -31  ? A TRP 10   
11  1 Y 1 A SER -30  ? A SER 11   
12  1 Y 1 A HIS -29  ? A HIS 12   
13  1 Y 1 A PRO -28  ? A PRO 13   
14  1 Y 1 A GLN -27  ? A GLN 14   
15  1 Y 1 A PHE -26  ? A PHE 15   
16  1 Y 1 A GLU -25  ? A GLU 16   
17  1 Y 1 A LYS -24  ? A LYS 17   
18  1 Y 1 A GLY -23  ? A GLY 18   
19  1 Y 1 A GLY -22  ? A GLY 19   
20  1 Y 1 A GLY -21  ? A GLY 20   
21  1 Y 1 A GLY -20  ? A GLY 21   
22  1 Y 1 A SER -19  ? A SER 22   
23  1 Y 1 A GLY -18  ? A GLY 23   
24  1 Y 1 A GLY -17  ? A GLY 24   
25  1 Y 1 A SER -16  ? A SER 25   
26  1 Y 1 A ALA -15  ? A ALA 26   
27  1 Y 1 A TRP -14  ? A TRP 27   
28  1 Y 1 A SER -13  ? A SER 28   
29  1 Y 1 A HIS -12  ? A HIS 29   
30  1 Y 1 A PRO -11  ? A PRO 30   
31  1 Y 1 A GLN -10  ? A GLN 31   
32  1 Y 1 A PHE -9   ? A PHE 32   
33  1 Y 1 A GLU -8   ? A GLU 33   
34  1 Y 1 A LYS -7   ? A LYS 34   
35  1 Y 1 A GLU -6   ? A GLU 35   
36  1 Y 1 A PHE -5   ? A PHE 36   
37  1 Y 1 A LYS -4   ? A LYS 37   
38  1 Y 1 A GLY -3   ? A GLY 38   
39  1 Y 1 A LEU -2   ? A LEU 39   
40  1 Y 1 A VAL -1   ? A VAL 40   
41  1 Y 1 A ASP 0    ? A ASP 41   
42  1 Y 1 A MET 1    ? A MET 42   
43  1 Y 1 A ASP 2    ? A ASP 43   
44  1 Y 1 A ASN 3    ? A ASN 44   
45  1 Y 1 A ASP 4    ? A ASP 45   
46  1 Y 1 A GLY 5    ? A GLY 46   
47  1 Y 1 A GLY 6    ? A GLY 47   
48  1 Y 1 A ALA 7    ? A ALA 48   
49  1 Y 1 A PRO 8    ? A PRO 49   
50  1 Y 1 A PRO 9    ? A PRO 50   
51  1 Y 1 A PRO 10   ? A PRO 51   
52  1 Y 1 A PRO 11   ? A PRO 52   
53  1 Y 1 A PRO 12   ? A PRO 53   
54  1 Y 1 A THR 13   ? A THR 54   
55  1 Y 1 A LEU 14   ? A LEU 55   
56  1 Y 1 A VAL 15   ? A VAL 56   
57  1 Y 1 A VAL 16   ? A VAL 57   
58  1 Y 1 A GLU 17   ? A GLU 58   
59  1 Y 1 A GLU 18   ? A GLU 59   
60  1 Y 1 A PRO 19   ? A PRO 60   
61  1 Y 1 A LYS 20   ? A LYS 61   
62  1 Y 1 A LYS 21   ? A LYS 62   
63  1 Y 1 A ALA 22   ? A ALA 63   
64  1 Y 1 A VAL 599  ? A VAL 640  
65  1 Y 1 A TYR 600  ? A TYR 641  
66  1 Y 1 A ALA 601  ? A ALA 642  
67  1 Y 1 A LYS 602  ? A LYS 643  
68  1 Y 1 A LEU 603  ? A LEU 644  
69  1 Y 1 A ILE 604  ? A ILE 645  
70  1 Y 1 A LYS 605  ? A LYS 646  
71  1 Y 1 A MET 606  ? A MET 647  
72  1 Y 1 A GLN 607  ? A GLN 648  
73  1 Y 1 A GLU 608  ? A GLU 649  
74  1 Y 1 A ALA 609  ? A ALA 650  
75  1 Y 1 A ALA 610  ? A ALA 651  
76  1 Y 1 A HIS 611  ? A HIS 652  
77  1 Y 1 A GLU 612  ? A GLU 653  
78  1 Y 1 A THR 613  ? A THR 654  
79  1 Y 1 A ALA 614  ? A ALA 655  
80  1 Y 1 A MET 615  ? A MET 656  
81  1 Y 1 A SER 616  ? A SER 657  
82  1 Y 1 A ASN 617  ? A ASN 658  
83  1 Y 1 A ALA 618  ? A ALA 659  
84  1 Y 1 A ARG 619  ? A ARG 660  
85  1 Y 1 A LYS 620  ? A LYS 661  
86  1 Y 1 A SER 621  ? A SER 662  
87  1 Y 1 A SER 622  ? A SER 663  
88  1 Y 1 A ALA 623  ? A ALA 664  
89  1 Y 1 A ARG 624  ? A ARG 665  
90  1 Y 1 A PRO 625  ? A PRO 666  
91  1 Y 1 A SER 626  ? A SER 667  
92  1 Y 1 A SER 627  ? A SER 668  
93  1 Y 1 A ALA 628  ? A ALA 669  
94  1 Y 1 A ARG 629  ? A ARG 670  
95  1 Y 1 A ASN 630  ? A ASN 671  
96  1 Y 1 A SER 631  ? A SER 672  
97  1 Y 1 A VAL 632  ? A VAL 673  
98  1 Y 1 A SER 633  ? A SER 674  
99  1 Y 1 A SER 634  ? A SER 675  
100 1 Y 1 A PRO 635  ? A PRO 676  
101 1 Y 1 A ILE 636  ? A ILE 677  
102 1 Y 1 A MET 637  ? A MET 678  
103 1 Y 1 A THR 638  ? A THR 679  
104 1 Y 1 A ARG 639  ? A ARG 680  
105 1 Y 1 A ASN 640  ? A ASN 681  
106 1 Y 1 A SER 641  ? A SER 682  
107 1 Y 1 A SER 642  ? A SER 683  
108 1 Y 1 A TYR 643  ? A TYR 684  
109 1 Y 1 A GLY 644  ? A GLY 685  
110 1 Y 1 A ARG 645  ? A ARG 686  
111 1 Y 1 A SER 646  ? A SER 687  
112 1 Y 1 A PRO 647  ? A PRO 688  
113 1 Y 1 A TYR 648  ? A TYR 689  
114 1 Y 1 A SER 649  ? A SER 690  
115 1 Y 1 A ARG 650  ? A ARG 691  
116 1 Y 1 A ARG 651  ? A ARG 692  
117 1 Y 1 A LEU 652  ? A LEU 693  
118 1 Y 1 A SER 653  ? A SER 694  
119 1 Y 1 A ASP 654  ? A ASP 695  
120 1 Y 1 A PHE 655  ? A PHE 696  
121 1 Y 1 A SER 656  ? A SER 697  
122 1 Y 1 A THR 657  ? A THR 698  
123 1 Y 1 A SER 658  ? A SER 699  
124 1 Y 1 A ASP 659  ? A ASP 700  
125 1 Y 1 A PHE 660  ? A PHE 701  
126 1 Y 1 A SER 661  ? A SER 702  
127 1 Y 1 A LEU 662  ? A LEU 703  
128 1 Y 1 A SER 663  ? A SER 704  
129 1 Y 1 A ILE 664  ? A ILE 705  
130 1 Y 1 A ASP 665  ? A ASP 706  
131 1 Y 1 A ALA 666  ? A ALA 707  
132 1 Y 1 A SER 667  ? A SER 708  
133 1 Y 1 A SER 668  ? A SER 709  
134 1 Y 1 A TYR 669  ? A TYR 710  
135 1 Y 1 A PRO 670  ? A PRO 711  
136 1 Y 1 A ASN 671  ? A ASN 712  
137 1 Y 1 A TYR 672  ? A TYR 713  
138 1 Y 1 A ARG 673  ? A ARG 714  
139 1 Y 1 A ASN 674  ? A ASN 715  
140 1 Y 1 A GLU 675  ? A GLU 716  
141 1 Y 1 A PHE 1265 ? A PHE 1306 
142 1 Y 1 A THR 1266 ? A THR 1307 
143 1 Y 1 A HIS 1267 ? A HIS 1308 
144 1 Y 1 A THR 1268 ? A THR 1309 
145 1 Y 1 A GLN 1269 ? A GLN 1310 
146 1 Y 1 A VAL 1270 ? A VAL 1311 
147 1 Y 1 A ILE 1271 ? A ILE 1312 
148 1 Y 1 A GLY 1272 ? A GLY 1313 
149 1 Y 1 A MET 1273 ? A MET 1314 
150 1 Y 1 A THR 1274 ? A THR 1315 
151 1 Y 1 A SER 1275 ? A SER 1316 
152 1 Y 1 A GLY 1276 ? A GLY 1317 
153 1 Y 1 A SER 1277 ? A SER 1318 
154 1 Y 1 A SER 1278 ? A SER 1319 
155 1 Y 1 A SER 1279 ? A SER 1320 
156 1 Y 1 A ARG 1280 ? A ARG 1321 
157 1 Y 1 A VAL 1281 ? A VAL 1322 
158 1 Y 1 A LYS 1282 ? A LYS 1323 
159 1 Y 1 A GLU 1283 ? A GLU 1324 
160 1 Y 1 A ASP 1284 ? A ASP 1325 
161 1 Y 1 A ASP 1285 ? A ASP 1326 
162 1 Y 1 A ALA 1286 ? A ALA 1327 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BLD C01  C N N 74  
BLD C02  C N R 75  
BLD O02  O N N 76  
BLD C03  C N S 77  
BLD O03  O N N 78  
BLD C04  C N N 79  
BLD C05  C N S 80  
BLD C06  C N N 81  
BLD O06  O N N 82  
BLD C07  C N N 83  
BLD O07  O N N 84  
BLD C08  C N S 85  
BLD C09  C N S 86  
BLD C10  C N R 87  
BLD C11  C N N 88  
BLD C12  C N N 89  
BLD C13  C N S 90  
BLD C14  C N S 91  
BLD C15  C N N 92  
BLD C16  C N N 93  
BLD C17  C N R 94  
BLD C18  C N N 95  
BLD C19  C N N 96  
BLD C20  C N S 97  
BLD C21  C N N 98  
BLD C22  C N R 99  
BLD O22  O N N 100 
BLD C23  C N R 101 
BLD O23  O N N 102 
BLD C24  C N S 103 
BLD C25  C N N 104 
BLD C26  C N N 105 
BLD C27  C N N 106 
BLD C28  C N N 107 
BLD H101 H N N 108 
BLD H201 H N N 109 
BLD H02  H N N 110 
BLD HO02 H N N 111 
BLD H03  H N N 112 
BLD HO03 H N N 113 
BLD H104 H N N 114 
BLD H204 H N N 115 
BLD H05  H N N 116 
BLD H107 H N N 117 
BLD H207 H N N 118 
BLD H08  H N N 119 
BLD H09  H N N 120 
BLD H111 H N N 121 
BLD H211 H N N 122 
BLD H112 H N N 123 
BLD H212 H N N 124 
BLD H14  H N N 125 
BLD H115 H N N 126 
BLD H215 H N N 127 
BLD H116 H N N 128 
BLD H216 H N N 129 
BLD H17  H N N 130 
BLD H118 H N N 131 
BLD H218 H N N 132 
BLD H318 H N N 133 
BLD H119 H N N 134 
BLD H219 H N N 135 
BLD H319 H N N 136 
BLD H20  H N N 137 
BLD H121 H N N 138 
BLD H221 H N N 139 
BLD H321 H N N 140 
BLD H22  H N N 141 
BLD HO22 H N N 142 
BLD H23  H N N 143 
BLD HO23 H N N 144 
BLD H24  H N N 145 
BLD H25  H N N 146 
BLD H126 H N N 147 
BLD H226 H N N 148 
BLD H326 H N N 149 
BLD H127 H N N 150 
BLD H227 H N N 151 
BLD H327 H N N 152 
BLD H128 H N N 153 
BLD H228 H N N 154 
BLD H328 H N N 155 
CYS N    N N N 156 
CYS CA   C N R 157 
CYS C    C N N 158 
CYS O    O N N 159 
CYS CB   C N N 160 
CYS SG   S N N 161 
CYS OXT  O N N 162 
CYS H    H N N 163 
CYS H2   H N N 164 
CYS HA   H N N 165 
CYS HB2  H N N 166 
CYS HB3  H N N 167 
CYS HG   H N N 168 
CYS HXT  H N N 169 
GLN N    N N N 170 
GLN CA   C N S 171 
GLN C    C N N 172 
GLN O    O N N 173 
GLN CB   C N N 174 
GLN CG   C N N 175 
GLN CD   C N N 176 
GLN OE1  O N N 177 
GLN NE2  N N N 178 
GLN OXT  O N N 179 
GLN H    H N N 180 
GLN H2   H N N 181 
GLN HA   H N N 182 
GLN HB2  H N N 183 
GLN HB3  H N N 184 
GLN HG2  H N N 185 
GLN HG3  H N N 186 
GLN HE21 H N N 187 
GLN HE22 H N N 188 
GLN HXT  H N N 189 
GLU N    N N N 190 
GLU CA   C N S 191 
GLU C    C N N 192 
GLU O    O N N 193 
GLU CB   C N N 194 
GLU CG   C N N 195 
GLU CD   C N N 196 
GLU OE1  O N N 197 
GLU OE2  O N N 198 
GLU OXT  O N N 199 
GLU H    H N N 200 
GLU H2   H N N 201 
GLU HA   H N N 202 
GLU HB2  H N N 203 
GLU HB3  H N N 204 
GLU HG2  H N N 205 
GLU HG3  H N N 206 
GLU HE2  H N N 207 
GLU HXT  H N N 208 
GLY N    N N N 209 
GLY CA   C N N 210 
GLY C    C N N 211 
GLY O    O N N 212 
GLY OXT  O N N 213 
GLY H    H N N 214 
GLY H2   H N N 215 
GLY HA2  H N N 216 
GLY HA3  H N N 217 
GLY HXT  H N N 218 
HIS N    N N N 219 
HIS CA   C N S 220 
HIS C    C N N 221 
HIS O    O N N 222 
HIS CB   C N N 223 
HIS CG   C Y N 224 
HIS ND1  N Y N 225 
HIS CD2  C Y N 226 
HIS CE1  C Y N 227 
HIS NE2  N Y N 228 
HIS OXT  O N N 229 
HIS H    H N N 230 
HIS H2   H N N 231 
HIS HA   H N N 232 
HIS HB2  H N N 233 
HIS HB3  H N N 234 
HIS HD1  H N N 235 
HIS HD2  H N N 236 
HIS HE1  H N N 237 
HIS HE2  H N N 238 
HIS HXT  H N N 239 
ILE N    N N N 240 
ILE CA   C N S 241 
ILE C    C N N 242 
ILE O    O N N 243 
ILE CB   C N S 244 
ILE CG1  C N N 245 
ILE CG2  C N N 246 
ILE CD1  C N N 247 
ILE OXT  O N N 248 
ILE H    H N N 249 
ILE H2   H N N 250 
ILE HA   H N N 251 
ILE HB   H N N 252 
ILE HG12 H N N 253 
ILE HG13 H N N 254 
ILE HG21 H N N 255 
ILE HG22 H N N 256 
ILE HG23 H N N 257 
ILE HD11 H N N 258 
ILE HD12 H N N 259 
ILE HD13 H N N 260 
ILE HXT  H N N 261 
LEU N    N N N 262 
LEU CA   C N S 263 
LEU C    C N N 264 
LEU O    O N N 265 
LEU CB   C N N 266 
LEU CG   C N N 267 
LEU CD1  C N N 268 
LEU CD2  C N N 269 
LEU OXT  O N N 270 
LEU H    H N N 271 
LEU H2   H N N 272 
LEU HA   H N N 273 
LEU HB2  H N N 274 
LEU HB3  H N N 275 
LEU HG   H N N 276 
LEU HD11 H N N 277 
LEU HD12 H N N 278 
LEU HD13 H N N 279 
LEU HD21 H N N 280 
LEU HD22 H N N 281 
LEU HD23 H N N 282 
LEU HXT  H N N 283 
LYS N    N N N 284 
LYS CA   C N S 285 
LYS C    C N N 286 
LYS O    O N N 287 
LYS CB   C N N 288 
LYS CG   C N N 289 
LYS CD   C N N 290 
LYS CE   C N N 291 
LYS NZ   N N N 292 
LYS OXT  O N N 293 
LYS H    H N N 294 
LYS H2   H N N 295 
LYS HA   H N N 296 
LYS HB2  H N N 297 
LYS HB3  H N N 298 
LYS HG2  H N N 299 
LYS HG3  H N N 300 
LYS HD2  H N N 301 
LYS HD3  H N N 302 
LYS HE2  H N N 303 
LYS HE3  H N N 304 
LYS HZ1  H N N 305 
LYS HZ2  H N N 306 
LYS HZ3  H N N 307 
LYS HXT  H N N 308 
MET N    N N N 309 
MET CA   C N S 310 
MET C    C N N 311 
MET O    O N N 312 
MET CB   C N N 313 
MET CG   C N N 314 
MET SD   S N N 315 
MET CE   C N N 316 
MET OXT  O N N 317 
MET H    H N N 318 
MET H2   H N N 319 
MET HA   H N N 320 
MET HB2  H N N 321 
MET HB3  H N N 322 
MET HG2  H N N 323 
MET HG3  H N N 324 
MET HE1  H N N 325 
MET HE2  H N N 326 
MET HE3  H N N 327 
MET HXT  H N N 328 
PHE N    N N N 329 
PHE CA   C N S 330 
PHE C    C N N 331 
PHE O    O N N 332 
PHE CB   C N N 333 
PHE CG   C Y N 334 
PHE CD1  C Y N 335 
PHE CD2  C Y N 336 
PHE CE1  C Y N 337 
PHE CE2  C Y N 338 
PHE CZ   C Y N 339 
PHE OXT  O N N 340 
PHE H    H N N 341 
PHE H2   H N N 342 
PHE HA   H N N 343 
PHE HB2  H N N 344 
PHE HB3  H N N 345 
PHE HD1  H N N 346 
PHE HD2  H N N 347 
PHE HE1  H N N 348 
PHE HE2  H N N 349 
PHE HZ   H N N 350 
PHE HXT  H N N 351 
PRO N    N N N 352 
PRO CA   C N S 353 
PRO C    C N N 354 
PRO O    O N N 355 
PRO CB   C N N 356 
PRO CG   C N N 357 
PRO CD   C N N 358 
PRO OXT  O N N 359 
PRO H    H N N 360 
PRO HA   H N N 361 
PRO HB2  H N N 362 
PRO HB3  H N N 363 
PRO HG2  H N N 364 
PRO HG3  H N N 365 
PRO HD2  H N N 366 
PRO HD3  H N N 367 
PRO HXT  H N N 368 
SER N    N N N 369 
SER CA   C N S 370 
SER C    C N N 371 
SER O    O N N 372 
SER CB   C N N 373 
SER OG   O N N 374 
SER OXT  O N N 375 
SER H    H N N 376 
SER H2   H N N 377 
SER HA   H N N 378 
SER HB2  H N N 379 
SER HB3  H N N 380 
SER HG   H N N 381 
SER HXT  H N N 382 
THR N    N N N 383 
THR CA   C N S 384 
THR C    C N N 385 
THR O    O N N 386 
THR CB   C N R 387 
THR OG1  O N N 388 
THR CG2  C N N 389 
THR OXT  O N N 390 
THR H    H N N 391 
THR H2   H N N 392 
THR HA   H N N 393 
THR HB   H N N 394 
THR HG1  H N N 395 
THR HG21 H N N 396 
THR HG22 H N N 397 
THR HG23 H N N 398 
THR HXT  H N N 399 
TRP N    N N N 400 
TRP CA   C N S 401 
TRP C    C N N 402 
TRP O    O N N 403 
TRP CB   C N N 404 
TRP CG   C Y N 405 
TRP CD1  C Y N 406 
TRP CD2  C Y N 407 
TRP NE1  N Y N 408 
TRP CE2  C Y N 409 
TRP CE3  C Y N 410 
TRP CZ2  C Y N 411 
TRP CZ3  C Y N 412 
TRP CH2  C Y N 413 
TRP OXT  O N N 414 
TRP H    H N N 415 
TRP H2   H N N 416 
TRP HA   H N N 417 
TRP HB2  H N N 418 
TRP HB3  H N N 419 
TRP HD1  H N N 420 
TRP HE1  H N N 421 
TRP HE3  H N N 422 
TRP HZ2  H N N 423 
TRP HZ3  H N N 424 
TRP HH2  H N N 425 
TRP HXT  H N N 426 
TYR N    N N N 427 
TYR CA   C N S 428 
TYR C    C N N 429 
TYR O    O N N 430 
TYR CB   C N N 431 
TYR CG   C Y N 432 
TYR CD1  C Y N 433 
TYR CD2  C Y N 434 
TYR CE1  C Y N 435 
TYR CE2  C Y N 436 
TYR CZ   C Y N 437 
TYR OH   O N N 438 
TYR OXT  O N N 439 
TYR H    H N N 440 
TYR H2   H N N 441 
TYR HA   H N N 442 
TYR HB2  H N N 443 
TYR HB3  H N N 444 
TYR HD1  H N N 445 
TYR HD2  H N N 446 
TYR HE1  H N N 447 
TYR HE2  H N N 448 
TYR HH   H N N 449 
TYR HXT  H N N 450 
VAL N    N N N 451 
VAL CA   C N S 452 
VAL C    C N N 453 
VAL O    O N N 454 
VAL CB   C N N 455 
VAL CG1  C N N 456 
VAL CG2  C N N 457 
VAL OXT  O N N 458 
VAL H    H N N 459 
VAL H2   H N N 460 
VAL HA   H N N 461 
VAL HB   H N N 462 
VAL HG11 H N N 463 
VAL HG12 H N N 464 
VAL HG13 H N N 465 
VAL HG21 H N N 466 
VAL HG22 H N N 467 
VAL HG23 H N N 468 
VAL HXT  H N N 469 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BLD C01 C10  sing N N 70  
BLD C01 H101 sing N N 71  
BLD C01 H201 sing N N 72  
BLD C02 C03  sing N N 73  
BLD C02 C01  sing N N 74  
BLD C02 H02  sing N N 75  
BLD O02 C02  sing N N 76  
BLD O02 HO02 sing N N 77  
BLD C03 C04  sing N N 78  
BLD C03 H03  sing N N 79  
BLD O03 C03  sing N N 80  
BLD O03 HO03 sing N N 81  
BLD C04 C05  sing N N 82  
BLD C04 H104 sing N N 83  
BLD C04 H204 sing N N 84  
BLD C05 C06  sing N N 85  
BLD C05 H05  sing N N 86  
BLD C06 O06  doub N N 87  
BLD C06 O07  sing N N 88  
BLD C07 O07  sing N N 89  
BLD C07 H107 sing N N 90  
BLD C07 H207 sing N N 91  
BLD C08 C07  sing N N 92  
BLD C08 H08  sing N N 93  
BLD C09 C11  sing N N 94  
BLD C09 C08  sing N N 95  
BLD C09 H09  sing N N 96  
BLD C10 C09  sing N N 97  
BLD C10 C05  sing N N 98  
BLD C10 C19  sing N N 99  
BLD C11 H111 sing N N 100 
BLD C11 H211 sing N N 101 
BLD C12 C11  sing N N 102 
BLD C12 C13  sing N N 103 
BLD C12 H112 sing N N 104 
BLD C12 H212 sing N N 105 
BLD C13 C14  sing N N 106 
BLD C13 C18  sing N N 107 
BLD C14 C08  sing N N 108 
BLD C14 C15  sing N N 109 
BLD C14 H14  sing N N 110 
BLD C15 H115 sing N N 111 
BLD C15 H215 sing N N 112 
BLD C16 C15  sing N N 113 
BLD C16 H116 sing N N 114 
BLD C16 H216 sing N N 115 
BLD C17 C13  sing N N 116 
BLD C17 C20  sing N N 117 
BLD C17 C16  sing N N 118 
BLD C17 H17  sing N N 119 
BLD C18 H118 sing N N 120 
BLD C18 H218 sing N N 121 
BLD C18 H318 sing N N 122 
BLD C19 H119 sing N N 123 
BLD C19 H219 sing N N 124 
BLD C19 H319 sing N N 125 
BLD C20 H20  sing N N 126 
BLD C21 C20  sing N N 127 
BLD C21 H121 sing N N 128 
BLD C21 H221 sing N N 129 
BLD C21 H321 sing N N 130 
BLD C22 C23  sing N N 131 
BLD C22 C20  sing N N 132 
BLD C22 H22  sing N N 133 
BLD O22 C22  sing N N 134 
BLD O22 HO22 sing N N 135 
BLD C23 C24  sing N N 136 
BLD C23 H23  sing N N 137 
BLD O23 C23  sing N N 138 
BLD O23 HO23 sing N N 139 
BLD C24 C25  sing N N 140 
BLD C24 C28  sing N N 141 
BLD C24 H24  sing N N 142 
BLD C25 C27  sing N N 143 
BLD C25 H25  sing N N 144 
BLD C26 C25  sing N N 145 
BLD C26 H126 sing N N 146 
BLD C26 H226 sing N N 147 
BLD C26 H326 sing N N 148 
BLD C27 H127 sing N N 149 
BLD C27 H227 sing N N 150 
BLD C27 H327 sing N N 151 
BLD C28 H128 sing N N 152 
BLD C28 H228 sing N N 153 
BLD C28 H328 sing N N 154 
CYS N   CA   sing N N 155 
CYS N   H    sing N N 156 
CYS N   H2   sing N N 157 
CYS CA  C    sing N N 158 
CYS CA  CB   sing N N 159 
CYS CA  HA   sing N N 160 
CYS C   O    doub N N 161 
CYS C   OXT  sing N N 162 
CYS CB  SG   sing N N 163 
CYS CB  HB2  sing N N 164 
CYS CB  HB3  sing N N 165 
CYS SG  HG   sing N N 166 
CYS OXT HXT  sing N N 167 
GLN N   CA   sing N N 168 
GLN N   H    sing N N 169 
GLN N   H2   sing N N 170 
GLN CA  C    sing N N 171 
GLN CA  CB   sing N N 172 
GLN CA  HA   sing N N 173 
GLN C   O    doub N N 174 
GLN C   OXT  sing N N 175 
GLN CB  CG   sing N N 176 
GLN CB  HB2  sing N N 177 
GLN CB  HB3  sing N N 178 
GLN CG  CD   sing N N 179 
GLN CG  HG2  sing N N 180 
GLN CG  HG3  sing N N 181 
GLN CD  OE1  doub N N 182 
GLN CD  NE2  sing N N 183 
GLN NE2 HE21 sing N N 184 
GLN NE2 HE22 sing N N 185 
GLN OXT HXT  sing N N 186 
GLU N   CA   sing N N 187 
GLU N   H    sing N N 188 
GLU N   H2   sing N N 189 
GLU CA  C    sing N N 190 
GLU CA  CB   sing N N 191 
GLU CA  HA   sing N N 192 
GLU C   O    doub N N 193 
GLU C   OXT  sing N N 194 
GLU CB  CG   sing N N 195 
GLU CB  HB2  sing N N 196 
GLU CB  HB3  sing N N 197 
GLU CG  CD   sing N N 198 
GLU CG  HG2  sing N N 199 
GLU CG  HG3  sing N N 200 
GLU CD  OE1  doub N N 201 
GLU CD  OE2  sing N N 202 
GLU OE2 HE2  sing N N 203 
GLU OXT HXT  sing N N 204 
GLY N   CA   sing N N 205 
GLY N   H    sing N N 206 
GLY N   H2   sing N N 207 
GLY CA  C    sing N N 208 
GLY CA  HA2  sing N N 209 
GLY CA  HA3  sing N N 210 
GLY C   O    doub N N 211 
GLY C   OXT  sing N N 212 
GLY OXT HXT  sing N N 213 
HIS N   CA   sing N N 214 
HIS N   H    sing N N 215 
HIS N   H2   sing N N 216 
HIS CA  C    sing N N 217 
HIS CA  CB   sing N N 218 
HIS CA  HA   sing N N 219 
HIS C   O    doub N N 220 
HIS C   OXT  sing N N 221 
HIS CB  CG   sing N N 222 
HIS CB  HB2  sing N N 223 
HIS CB  HB3  sing N N 224 
HIS CG  ND1  sing Y N 225 
HIS CG  CD2  doub Y N 226 
HIS ND1 CE1  doub Y N 227 
HIS ND1 HD1  sing N N 228 
HIS CD2 NE2  sing Y N 229 
HIS CD2 HD2  sing N N 230 
HIS CE1 NE2  sing Y N 231 
HIS CE1 HE1  sing N N 232 
HIS NE2 HE2  sing N N 233 
HIS OXT HXT  sing N N 234 
ILE N   CA   sing N N 235 
ILE N   H    sing N N 236 
ILE N   H2   sing N N 237 
ILE CA  C    sing N N 238 
ILE CA  CB   sing N N 239 
ILE CA  HA   sing N N 240 
ILE C   O    doub N N 241 
ILE C   OXT  sing N N 242 
ILE CB  CG1  sing N N 243 
ILE CB  CG2  sing N N 244 
ILE CB  HB   sing N N 245 
ILE CG1 CD1  sing N N 246 
ILE CG1 HG12 sing N N 247 
ILE CG1 HG13 sing N N 248 
ILE CG2 HG21 sing N N 249 
ILE CG2 HG22 sing N N 250 
ILE CG2 HG23 sing N N 251 
ILE CD1 HD11 sing N N 252 
ILE CD1 HD12 sing N N 253 
ILE CD1 HD13 sing N N 254 
ILE OXT HXT  sing N N 255 
LEU N   CA   sing N N 256 
LEU N   H    sing N N 257 
LEU N   H2   sing N N 258 
LEU CA  C    sing N N 259 
LEU CA  CB   sing N N 260 
LEU CA  HA   sing N N 261 
LEU C   O    doub N N 262 
LEU C   OXT  sing N N 263 
LEU CB  CG   sing N N 264 
LEU CB  HB2  sing N N 265 
LEU CB  HB3  sing N N 266 
LEU CG  CD1  sing N N 267 
LEU CG  CD2  sing N N 268 
LEU CG  HG   sing N N 269 
LEU CD1 HD11 sing N N 270 
LEU CD1 HD12 sing N N 271 
LEU CD1 HD13 sing N N 272 
LEU CD2 HD21 sing N N 273 
LEU CD2 HD22 sing N N 274 
LEU CD2 HD23 sing N N 275 
LEU OXT HXT  sing N N 276 
LYS N   CA   sing N N 277 
LYS N   H    sing N N 278 
LYS N   H2   sing N N 279 
LYS CA  C    sing N N 280 
LYS CA  CB   sing N N 281 
LYS CA  HA   sing N N 282 
LYS C   O    doub N N 283 
LYS C   OXT  sing N N 284 
LYS CB  CG   sing N N 285 
LYS CB  HB2  sing N N 286 
LYS CB  HB3  sing N N 287 
LYS CG  CD   sing N N 288 
LYS CG  HG2  sing N N 289 
LYS CG  HG3  sing N N 290 
LYS CD  CE   sing N N 291 
LYS CD  HD2  sing N N 292 
LYS CD  HD3  sing N N 293 
LYS CE  NZ   sing N N 294 
LYS CE  HE2  sing N N 295 
LYS CE  HE3  sing N N 296 
LYS NZ  HZ1  sing N N 297 
LYS NZ  HZ2  sing N N 298 
LYS NZ  HZ3  sing N N 299 
LYS OXT HXT  sing N N 300 
MET N   CA   sing N N 301 
MET N   H    sing N N 302 
MET N   H2   sing N N 303 
MET CA  C    sing N N 304 
MET CA  CB   sing N N 305 
MET CA  HA   sing N N 306 
MET C   O    doub N N 307 
MET C   OXT  sing N N 308 
MET CB  CG   sing N N 309 
MET CB  HB2  sing N N 310 
MET CB  HB3  sing N N 311 
MET CG  SD   sing N N 312 
MET CG  HG2  sing N N 313 
MET CG  HG3  sing N N 314 
MET SD  CE   sing N N 315 
MET CE  HE1  sing N N 316 
MET CE  HE2  sing N N 317 
MET CE  HE3  sing N N 318 
MET OXT HXT  sing N N 319 
PHE N   CA   sing N N 320 
PHE N   H    sing N N 321 
PHE N   H2   sing N N 322 
PHE CA  C    sing N N 323 
PHE CA  CB   sing N N 324 
PHE CA  HA   sing N N 325 
PHE C   O    doub N N 326 
PHE C   OXT  sing N N 327 
PHE CB  CG   sing N N 328 
PHE CB  HB2  sing N N 329 
PHE CB  HB3  sing N N 330 
PHE CG  CD1  doub Y N 331 
PHE CG  CD2  sing Y N 332 
PHE CD1 CE1  sing Y N 333 
PHE CD1 HD1  sing N N 334 
PHE CD2 CE2  doub Y N 335 
PHE CD2 HD2  sing N N 336 
PHE CE1 CZ   doub Y N 337 
PHE CE1 HE1  sing N N 338 
PHE CE2 CZ   sing Y N 339 
PHE CE2 HE2  sing N N 340 
PHE CZ  HZ   sing N N 341 
PHE OXT HXT  sing N N 342 
PRO N   CA   sing N N 343 
PRO N   CD   sing N N 344 
PRO N   H    sing N N 345 
PRO CA  C    sing N N 346 
PRO CA  CB   sing N N 347 
PRO CA  HA   sing N N 348 
PRO C   O    doub N N 349 
PRO C   OXT  sing N N 350 
PRO CB  CG   sing N N 351 
PRO CB  HB2  sing N N 352 
PRO CB  HB3  sing N N 353 
PRO CG  CD   sing N N 354 
PRO CG  HG2  sing N N 355 
PRO CG  HG3  sing N N 356 
PRO CD  HD2  sing N N 357 
PRO CD  HD3  sing N N 358 
PRO OXT HXT  sing N N 359 
SER N   CA   sing N N 360 
SER N   H    sing N N 361 
SER N   H2   sing N N 362 
SER CA  C    sing N N 363 
SER CA  CB   sing N N 364 
SER CA  HA   sing N N 365 
SER C   O    doub N N 366 
SER C   OXT  sing N N 367 
SER CB  OG   sing N N 368 
SER CB  HB2  sing N N 369 
SER CB  HB3  sing N N 370 
SER OG  HG   sing N N 371 
SER OXT HXT  sing N N 372 
THR N   CA   sing N N 373 
THR N   H    sing N N 374 
THR N   H2   sing N N 375 
THR CA  C    sing N N 376 
THR CA  CB   sing N N 377 
THR CA  HA   sing N N 378 
THR C   O    doub N N 379 
THR C   OXT  sing N N 380 
THR CB  OG1  sing N N 381 
THR CB  CG2  sing N N 382 
THR CB  HB   sing N N 383 
THR OG1 HG1  sing N N 384 
THR CG2 HG21 sing N N 385 
THR CG2 HG22 sing N N 386 
THR CG2 HG23 sing N N 387 
THR OXT HXT  sing N N 388 
TRP N   CA   sing N N 389 
TRP N   H    sing N N 390 
TRP N   H2   sing N N 391 
TRP CA  C    sing N N 392 
TRP CA  CB   sing N N 393 
TRP CA  HA   sing N N 394 
TRP C   O    doub N N 395 
TRP C   OXT  sing N N 396 
TRP CB  CG   sing N N 397 
TRP CB  HB2  sing N N 398 
TRP CB  HB3  sing N N 399 
TRP CG  CD1  doub Y N 400 
TRP CG  CD2  sing Y N 401 
TRP CD1 NE1  sing Y N 402 
TRP CD1 HD1  sing N N 403 
TRP CD2 CE2  doub Y N 404 
TRP CD2 CE3  sing Y N 405 
TRP NE1 CE2  sing Y N 406 
TRP NE1 HE1  sing N N 407 
TRP CE2 CZ2  sing Y N 408 
TRP CE3 CZ3  doub Y N 409 
TRP CE3 HE3  sing N N 410 
TRP CZ2 CH2  doub Y N 411 
TRP CZ2 HZ2  sing N N 412 
TRP CZ3 CH2  sing Y N 413 
TRP CZ3 HZ3  sing N N 414 
TRP CH2 HH2  sing N N 415 
TRP OXT HXT  sing N N 416 
TYR N   CA   sing N N 417 
TYR N   H    sing N N 418 
TYR N   H2   sing N N 419 
TYR CA  C    sing N N 420 
TYR CA  CB   sing N N 421 
TYR CA  HA   sing N N 422 
TYR C   O    doub N N 423 
TYR C   OXT  sing N N 424 
TYR CB  CG   sing N N 425 
TYR CB  HB2  sing N N 426 
TYR CB  HB3  sing N N 427 
TYR CG  CD1  doub Y N 428 
TYR CG  CD2  sing Y N 429 
TYR CD1 CE1  sing Y N 430 
TYR CD1 HD1  sing N N 431 
TYR CD2 CE2  doub Y N 432 
TYR CD2 HD2  sing N N 433 
TYR CE1 CZ   doub Y N 434 
TYR CE1 HE1  sing N N 435 
TYR CE2 CZ   sing Y N 436 
TYR CE2 HE2  sing N N 437 
TYR CZ  OH   sing N N 438 
TYR OH  HH   sing N N 439 
TYR OXT HXT  sing N N 440 
VAL N   CA   sing N N 441 
VAL N   H    sing N N 442 
VAL N   H2   sing N N 443 
VAL CA  C    sing N N 444 
VAL CA  CB   sing N N 445 
VAL CA  HA   sing N N 446 
VAL C   O    doub N N 447 
VAL C   OXT  sing N N 448 
VAL CB  CG1  sing N N 449 
VAL CB  CG2  sing N N 450 
VAL CB  HB   sing N N 451 
VAL CG1 HG11 sing N N 452 
VAL CG1 HG12 sing N N 453 
VAL CG1 HG13 sing N N 454 
VAL CG2 HG21 sing N N 455 
VAL CG2 HG22 sing N N 456 
VAL CG2 HG23 sing N N 457 
VAL OXT HXT  sing N N 458 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-08 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JUL 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-03-05 
_em_admin.title              'Structure of Arabidopsis thaliana ABCB1 with brassinolide bound in the inward-facing conformation' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          3702 
_em_entity_assembly_naturalsource.organism             'Arabidopsis thaliana' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         52 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 QUANTUM (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32400995 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9JUL 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLU A 1 64   ? 105.149 104.788 70.937  1.00 138.35 ? 23   GLU A N   1 
ATOM   2    C CA  . GLU A 1 64   ? 105.529 104.395 72.289  1.00 138.35 ? 23   GLU A CA  1 
ATOM   3    C C   . GLU A 1 64   ? 105.103 102.960 72.584  1.00 138.35 ? 23   GLU A C   1 
ATOM   4    O O   . GLU A 1 64   ? 103.959 102.581 72.333  1.00 138.35 ? 23   GLU A O   1 
ATOM   5    C CB  . GLU A 1 64   ? 104.916 105.347 73.317  1.00 138.35 ? 23   GLU A CB  1 
ATOM   6    C CG  . GLU A 1 64   ? 105.197 104.960 74.760  1.00 138.35 ? 23   GLU A CG  1 
ATOM   7    C CD  . GLU A 1 64   ? 106.670 104.719 75.017  1.00 138.35 ? 23   GLU A CD  1 
ATOM   8    O OE1 . GLU A 1 64   ? 107.485 105.606 74.688  1.00 138.35 ? 23   GLU A OE1 1 
ATOM   9    O OE2 . GLU A 1 64   ? 107.015 103.641 75.543  1.00 138.35 ? 23   GLU A OE2 1 
ATOM   10   N N   . ILE A 1 65   ? 106.031 102.167 73.121  1.00 124.96 ? 24   ILE A N   1 
ATOM   11   C CA  . ILE A 1 65   ? 105.729 100.780 73.448  1.00 124.96 ? 24   ILE A CA  1 
ATOM   12   C C   . ILE A 1 65   ? 104.752 100.726 74.618  1.00 124.96 ? 24   ILE A C   1 
ATOM   13   O O   . ILE A 1 65   ? 104.716 101.621 75.475  1.00 124.96 ? 24   ILE A O   1 
ATOM   14   C CB  . ILE A 1 65   ? 107.021 100.000 73.757  1.00 124.96 ? 24   ILE A CB  1 
ATOM   15   C CG1 . ILE A 1 65   ? 106.771 98.491  73.689  1.00 124.96 ? 24   ILE A CG1 1 
ATOM   16   C CG2 . ILE A 1 65   ? 107.582 100.395 75.117  1.00 124.96 ? 24   ILE A CG2 1 
ATOM   17   C CD1 . ILE A 1 65   ? 108.023 97.674  73.459  1.00 124.96 ? 24   ILE A CD1 1 
ATOM   18   N N   . ARG A 1 66   ? 103.937 99.676  74.645  1.00 113.59 ? 25   ARG A N   1 
ATOM   19   C CA  . ARG A 1 66   ? 102.959 99.483  75.706  1.00 113.59 ? 25   ARG A CA  1 
ATOM   20   C C   . ARG A 1 66   ? 103.588 98.698  76.848  1.00 113.59 ? 25   ARG A C   1 
ATOM   21   O O   . ARG A 1 66   ? 104.089 97.588  76.645  1.00 113.59 ? 25   ARG A O   1 
ATOM   22   C CB  . ARG A 1 66   ? 101.724 98.755  75.177  1.00 113.59 ? 25   ARG A CB  1 
ATOM   23   C CG  . ARG A 1 66   ? 100.598 98.620  76.191  1.00 113.59 ? 25   ARG A CG  1 
ATOM   24   C CD  . ARG A 1 66   ? 100.292 99.947  76.868  1.00 113.59 ? 25   ARG A CD  1 
ATOM   25   N NE  . ARG A 1 66   ? 100.061 101.018 75.906  1.00 113.59 ? 25   ARG A NE  1 
ATOM   26   C CZ  . ARG A 1 66   ? 100.361 102.291 76.119  1.00 113.59 ? 25   ARG A CZ  1 
ATOM   27   N NH1 . ARG A 1 66   ? 100.910 102.692 77.254  1.00 113.59 ? 25   ARG A NH1 1 
ATOM   28   N NH2 . ARG A 1 66   ? 100.104 103.186 75.170  1.00 113.59 ? 25   ARG A NH2 1 
ATOM   29   N N   . GLY A 1 67   ? 103.561 99.281  78.044  1.00 92.76  ? 26   GLY A N   1 
ATOM   30   C CA  . GLY A 1 67   ? 104.153 98.613  79.190  1.00 92.76  ? 26   GLY A CA  1 
ATOM   31   C C   . GLY A 1 67   ? 103.438 97.312  79.501  1.00 92.76  ? 26   GLY A C   1 
ATOM   32   O O   . GLY A 1 67   ? 102.218 97.200  79.364  1.00 92.76  ? 26   GLY A O   1 
ATOM   33   N N   . VAL A 1 68   ? 104.208 96.322  79.922  1.00 73.49  ? 27   VAL A N   1 
ATOM   34   C CA  . VAL A 1 68   ? 103.660 95.023  80.273  1.00 73.49  ? 27   VAL A CA  1 
ATOM   35   C C   . VAL A 1 68   ? 103.012 95.124  81.648  1.00 73.49  ? 27   VAL A C   1 
ATOM   36   O O   . VAL A 1 68   ? 103.375 95.967  82.472  1.00 73.49  ? 27   VAL A O   1 
ATOM   37   C CB  . VAL A 1 68   ? 104.748 93.931  80.235  1.00 73.49  ? 27   VAL A CB  1 
ATOM   38   C CG1 . VAL A 1 68   ? 105.709 94.086  81.404  1.00 73.49  ? 27   VAL A CG1 1 
ATOM   39   C CG2 . VAL A 1 68   ? 104.128 92.548  80.197  1.00 73.49  ? 27   VAL A CG2 1 
ATOM   40   N N   . ALA A 1 69   ? 102.028 94.264  81.898  1.00 69.67  ? 28   ALA A N   1 
ATOM   41   C CA  . ALA A 1 69   ? 101.320 94.301  83.169  1.00 69.67  ? 28   ALA A CA  1 
ATOM   42   C C   . ALA A 1 69   ? 102.254 93.924  84.313  1.00 69.67  ? 28   ALA A C   1 
ATOM   43   O O   . ALA A 1 69   ? 103.325 93.348  84.107  1.00 69.67  ? 28   ALA A O   1 
ATOM   44   C CB  . ALA A 1 69   ? 100.110 93.367  83.140  1.00 69.67  ? 28   ALA A CB  1 
ATOM   45   N N   . PHE A 1 70   ? 101.833 94.262  85.534  1.00 64.34  ? 29   PHE A N   1 
ATOM   46   C CA  . PHE A 1 70   ? 102.713 94.139  86.692  1.00 64.34  ? 29   PHE A CA  1 
ATOM   47   C C   . PHE A 1 70   ? 103.148 92.702  86.936  1.00 64.34  ? 29   PHE A C   1 
ATOM   48   O O   . PHE A 1 70   ? 104.325 92.453  87.222  1.00 64.34  ? 29   PHE A O   1 
ATOM   49   C CB  . PHE A 1 70   ? 102.018 94.692  87.935  1.00 64.34  ? 29   PHE A CB  1 
ATOM   50   C CG  . PHE A 1 70   ? 102.931 94.867  89.110  1.00 64.34  ? 29   PHE A CG  1 
ATOM   51   C CD1 . PHE A 1 70   ? 104.022 95.713  89.036  1.00 64.34  ? 29   PHE A CD1 1 
ATOM   52   C CD2 . PHE A 1 70   ? 102.707 94.173  90.286  1.00 64.34  ? 29   PHE A CD2 1 
ATOM   53   C CE1 . PHE A 1 70   ? 104.864 95.872  90.113  1.00 64.34  ? 29   PHE A CE1 1 
ATOM   54   C CE2 . PHE A 1 70   ? 103.548 94.328  91.366  1.00 64.34  ? 29   PHE A CE2 1 
ATOM   55   C CZ  . PHE A 1 70   ? 104.628 95.179  91.279  1.00 64.34  ? 29   PHE A CZ  1 
ATOM   56   N N   . LYS A 1 71   ? 102.226 91.745  86.822  1.00 68.61  ? 30   LYS A N   1 
ATOM   57   C CA  . LYS A 1 71   ? 102.537 90.365  87.180  1.00 68.61  ? 30   LYS A CA  1 
ATOM   58   C C   . LYS A 1 71   ? 103.683 89.809  86.343  1.00 68.61  ? 30   LYS A C   1 
ATOM   59   O O   . LYS A 1 71   ? 104.519 89.048  86.849  1.00 68.61  ? 30   LYS A O   1 
ATOM   60   C CB  . LYS A 1 71   ? 101.285 89.501  87.036  1.00 68.61  ? 30   LYS A CB  1 
ATOM   61   C CG  . LYS A 1 71   ? 100.558 89.684  85.717  1.00 68.61  ? 30   LYS A CG  1 
ATOM   62   C CD  . LYS A 1 71   ? 99.193  89.018  85.738  1.00 68.61  ? 30   LYS A CD  1 
ATOM   63   C CE  . LYS A 1 71   ? 98.277  89.676  86.757  1.00 68.61  ? 30   LYS A CE  1 
ATOM   64   N NZ  . LYS A 1 71   ? 96.931  89.041  86.792  1.00 68.61  ? 30   LYS A NZ  1 
ATOM   65   N N   . GLU A 1 72   ? 103.759 90.196  85.066  1.00 67.33  ? 31   GLU A N   1 
ATOM   66   C CA  . GLU A 1 72   ? 104.813 89.678  84.200  1.00 67.33  ? 31   GLU A CA  1 
ATOM   67   C C   . GLU A 1 72   ? 106.198 90.090  84.678  1.00 67.33  ? 31   GLU A C   1 
ATOM   68   O O   . GLU A 1 72   ? 107.193 89.467  84.290  1.00 67.33  ? 31   GLU A O   1 
ATOM   69   C CB  . GLU A 1 72   ? 104.602 90.141  82.760  1.00 67.33  ? 31   GLU A CB  1 
ATOM   70   C CG  . GLU A 1 72   ? 103.518 89.388  82.012  1.00 67.33  ? 31   GLU A CG  1 
ATOM   71   C CD  . GLU A 1 72   ? 102.138 89.941  82.278  1.00 67.33  ? 31   GLU A CD  1 
ATOM   72   O OE1 . GLU A 1 72   ? 102.037 90.942  83.015  1.00 67.33  ? 31   GLU A OE1 1 
ATOM   73   O OE2 . GLU A 1 72   ? 101.157 89.381  81.748  1.00 67.33  ? 31   GLU A OE2 1 
ATOM   74   N N   . LEU A 1 73   ? 106.291 91.127  85.512  1.00 60.53  ? 32   LEU A N   1 
ATOM   75   C CA  . LEU A 1 73   ? 107.586 91.498  86.067  1.00 60.53  ? 32   LEU A CA  1 
ATOM   76   C C   . LEU A 1 73   ? 108.194 90.378  86.896  1.00 60.53  ? 32   LEU A C   1 
ATOM   77   O O   . LEU A 1 73   ? 109.413 90.355  87.088  1.00 60.53  ? 32   LEU A O   1 
ATOM   78   C CB  . LEU A 1 73   ? 107.465 92.758  86.920  1.00 60.53  ? 32   LEU A CB  1 
ATOM   79   C CG  . LEU A 1 73   ? 107.585 94.104  86.210  1.00 60.53  ? 32   LEU A CG  1 
ATOM   80   C CD1 . LEU A 1 73   ? 106.336 94.410  85.413  1.00 60.53  ? 32   LEU A CD1 1 
ATOM   81   C CD2 . LEU A 1 73   ? 107.856 95.200  87.220  1.00 60.53  ? 32   LEU A CD2 1 
ATOM   82   N N   . PHE A 1 74   ? 107.375 89.447  87.385  1.00 60.83  ? 33   PHE A N   1 
ATOM   83   C CA  . PHE A 1 74   ? 107.844 88.334  88.199  1.00 60.83  ? 33   PHE A CA  1 
ATOM   84   C C   . PHE A 1 74   ? 107.936 87.036  87.404  1.00 60.83  ? 33   PHE A C   1 
ATOM   85   O O   . PHE A 1 74   ? 107.702 85.954  87.950  1.00 60.83  ? 33   PHE A O   1 
ATOM   86   C CB  . PHE A 1 74   ? 106.934 88.164  89.412  1.00 60.83  ? 33   PHE A CB  1 
ATOM   87   C CG  . PHE A 1 74   ? 106.719 89.434  90.176  1.00 60.83  ? 33   PHE A CG  1 
ATOM   88   C CD1 . PHE A 1 74   ? 107.712 89.941  90.992  1.00 60.83  ? 33   PHE A CD1 1 
ATOM   89   C CD2 . PHE A 1 74   ? 105.540 90.142  90.046  1.00 60.83  ? 33   PHE A CD2 1 
ATOM   90   C CE1 . PHE A 1 74   ? 107.522 91.115  91.685  1.00 60.83  ? 33   PHE A CE1 1 
ATOM   91   C CE2 . PHE A 1 74   ? 105.348 91.318  90.734  1.00 60.83  ? 33   PHE A CE2 1 
ATOM   92   C CZ  . PHE A 1 74   ? 106.340 91.804  91.555  1.00 60.83  ? 33   PHE A CZ  1 
ATOM   93   N N   . ARG A 1 75   ? 108.266 87.132  86.115  1.00 67.53  ? 34   ARG A N   1 
ATOM   94   C CA  . ARG A 1 75   ? 108.385 85.939  85.284  1.00 67.53  ? 34   ARG A CA  1 
ATOM   95   C C   . ARG A 1 75   ? 109.517 85.039  85.762  1.00 67.53  ? 34   ARG A C   1 
ATOM   96   O O   . ARG A 1 75   ? 109.383 83.810  85.767  1.00 67.53  ? 34   ARG A O   1 
ATOM   97   C CB  . ARG A 1 75   ? 108.600 86.342  83.826  1.00 67.53  ? 34   ARG A CB  1 
ATOM   98   C CG  . ARG A 1 75   ? 108.980 85.190  82.916  1.00 67.53  ? 34   ARG A CG  1 
ATOM   99   C CD  . ARG A 1 75   ? 109.475 85.680  81.568  1.00 67.53  ? 34   ARG A CD  1 
ATOM   100  N NE  . ARG A 1 75   ? 108.423 86.339  80.805  1.00 67.53  ? 34   ARG A NE  1 
ATOM   101  C CZ  . ARG A 1 75   ? 108.564 86.781  79.563  1.00 67.53  ? 34   ARG A CZ  1 
ATOM   102  N NH1 . ARG A 1 75   ? 109.703 86.645  78.908  1.00 67.53  ? 34   ARG A NH1 1 
ATOM   103  N NH2 . ARG A 1 75   ? 107.534 87.370  78.965  1.00 67.53  ? 34   ARG A NH2 1 
ATOM   104  N N   . PHE A 1 76   ? 110.635 85.629  86.167  1.00 62.85  ? 35   PHE A N   1 
ATOM   105  C CA  . PHE A 1 76   ? 111.834 84.886  86.526  1.00 62.85  ? 35   PHE A CA  1 
ATOM   106  C C   . PHE A 1 76   ? 111.907 84.541  88.007  1.00 62.85  ? 35   PHE A C   1 
ATOM   107  O O   . PHE A 1 76   ? 113.009 84.359  88.532  1.00 62.85  ? 35   PHE A O   1 
ATOM   108  C CB  . PHE A 1 76   ? 113.071 85.680  86.110  1.00 62.85  ? 35   PHE A CB  1 
ATOM   109  C CG  . PHE A 1 76   ? 113.093 86.026  84.654  1.00 62.85  ? 35   PHE A CG  1 
ATOM   110  C CD1 . PHE A 1 76   ? 113.541 85.111  83.720  1.00 62.85  ? 35   PHE A CD1 1 
ATOM   111  C CD2 . PHE A 1 76   ? 112.630 87.251  84.215  1.00 62.85  ? 35   PHE A CD2 1 
ATOM   112  C CE1 . PHE A 1 76   ? 113.553 85.421  82.379  1.00 62.85  ? 35   PHE A CE1 1 
ATOM   113  C CE2 . PHE A 1 76   ? 112.636 87.566  82.875  1.00 62.85  ? 35   PHE A CE2 1 
ATOM   114  C CZ  . PHE A 1 76   ? 113.099 86.650  81.956  1.00 62.85  ? 35   PHE A CZ  1 
ATOM   115  N N   . ALA A 1 77   ? 110.768 84.445  88.686  1.00 58.48  ? 36   ALA A N   1 
ATOM   116  C CA  . ALA A 1 77   ? 110.749 84.125  90.107  1.00 58.48  ? 36   ALA A CA  1 
ATOM   117  C C   . ALA A 1 77   ? 110.564 82.625  90.298  1.00 58.48  ? 36   ALA A C   1 
ATOM   118  O O   . ALA A 1 77   ? 109.587 82.048  89.810  1.00 58.48  ? 36   ALA A O   1 
ATOM   119  C CB  . ALA A 1 77   ? 109.638 84.899  90.809  1.00 58.48  ? 36   ALA A CB  1 
ATOM   120  N N   . ASP A 1 78   ? 111.500 81.997  91.004  1.00 56.89  ? 37   ASP A N   1 
ATOM   121  C CA  . ASP A 1 78   ? 111.396 80.587  91.344  1.00 56.89  ? 37   ASP A CA  1 
ATOM   122  C C   . ASP A 1 78   ? 110.802 80.430  92.743  1.00 56.89  ? 37   ASP A C   1 
ATOM   123  O O   . ASP A 1 78   ? 110.289 81.379  93.340  1.00 56.89  ? 37   ASP A O   1 
ATOM   124  C CB  . ASP A 1 78   ? 112.758 79.905  91.225  1.00 56.89  ? 37   ASP A CB  1 
ATOM   125  C CG  . ASP A 1 78   ? 113.815 80.549  92.095  1.00 56.89  ? 37   ASP A CG  1 
ATOM   126  O OD1 . ASP A 1 78   ? 113.531 81.596  92.706  1.00 56.89  ? 37   ASP A OD1 1 
ATOM   127  O OD2 . ASP A 1 78   ? 114.936 80.006  92.167  1.00 56.89  ? 37   ASP A OD2 1 
ATOM   128  N N   . GLY A 1 79   ? 110.857 79.206  93.270  1.00 54.94  ? 38   GLY A N   1 
ATOM   129  C CA  . GLY A 1 79   ? 110.256 78.942  94.569  1.00 54.94  ? 38   GLY A CA  1 
ATOM   130  C C   . GLY A 1 79   ? 110.910 79.716  95.694  1.00 54.94  ? 38   GLY A C   1 
ATOM   131  O O   . GLY A 1 79   ? 110.232 80.270  96.562  1.00 54.94  ? 38   GLY A O   1 
ATOM   132  N N   . LEU A 1 80   ? 112.245 79.762  95.699  1.00 50.86  ? 39   LEU A N   1 
ATOM   133  C CA  . LEU A 1 80   ? 112.944 80.511  96.736  1.00 50.86  ? 39   LEU A CA  1 
ATOM   134  C C   . LEU A 1 80   ? 112.603 81.991  96.666  1.00 50.86  ? 39   LEU A C   1 
ATOM   135  O O   . LEU A 1 80   ? 112.450 82.650  97.699  1.00 50.86  ? 39   LEU A O   1 
ATOM   136  C CB  . LEU A 1 80   ? 114.451 80.306  96.617  1.00 50.86  ? 39   LEU A CB  1 
ATOM   137  C CG  . LEU A 1 80   ? 115.282 81.150  97.584  1.00 50.86  ? 39   LEU A CG  1 
ATOM   138  C CD1 . LEU A 1 80   ? 115.001 80.745  99.015  1.00 50.86  ? 39   LEU A CD1 1 
ATOM   139  C CD2 . LEU A 1 80   ? 116.764 81.041  97.279  1.00 50.86  ? 39   LEU A CD2 1 
ATOM   140  N N   . ASP A 1 81   ? 112.475 82.533  95.454  1.00 51.78  ? 40   ASP A N   1 
ATOM   141  C CA  . ASP A 1 81   ? 112.089 83.932  95.314  1.00 51.78  ? 40   ASP A CA  1 
ATOM   142  C C   . ASP A 1 81   ? 110.678 84.165  95.833  1.00 51.78  ? 40   ASP A C   1 
ATOM   143  O O   . ASP A 1 81   ? 110.394 85.209  96.426  1.00 51.78  ? 40   ASP A O   1 
ATOM   144  C CB  . ASP A 1 81   ? 112.212 84.369  93.857  1.00 51.78  ? 40   ASP A CB  1 
ATOM   145  C CG  . ASP A 1 81   ? 113.652 84.505  93.414  1.00 51.78  ? 40   ASP A CG  1 
ATOM   146  O OD1 . ASP A 1 81   ? 114.552 84.373  94.268  1.00 51.78  ? 40   ASP A OD1 1 
ATOM   147  O OD2 . ASP A 1 81   ? 113.888 84.732  92.210  1.00 51.78  ? 40   ASP A OD2 1 
ATOM   148  N N   . TYR A 1 82   ? 109.777 83.205  95.622  1.00 53.72  ? 41   TYR A N   1 
ATOM   149  C CA  . TYR A 1 82   ? 108.428 83.329  96.163  1.00 53.72  ? 41   TYR A CA  1 
ATOM   150  C C   . TYR A 1 82   ? 108.444 83.326  97.686  1.00 53.72  ? 41   TYR A C   1 
ATOM   151  O O   . TYR A 1 82   ? 107.748 84.121  98.330  1.00 53.72  ? 41   TYR A O   1 
ATOM   152  C CB  . TYR A 1 82   ? 107.546 82.203  95.628  1.00 53.72  ? 41   TYR A CB  1 
ATOM   153  C CG  . TYR A 1 82   ? 106.902 82.527  94.305  1.00 53.72  ? 41   TYR A CG  1 
ATOM   154  C CD1 . TYR A 1 82   ? 106.231 83.725  94.116  1.00 53.72  ? 41   TYR A CD1 1 
ATOM   155  C CD2 . TYR A 1 82   ? 106.968 81.638  93.244  1.00 53.72  ? 41   TYR A CD2 1 
ATOM   156  C CE1 . TYR A 1 82   ? 105.641 84.029  92.908  1.00 53.72  ? 41   TYR A CE1 1 
ATOM   157  C CE2 . TYR A 1 82   ? 106.381 81.933  92.031  1.00 53.72  ? 41   TYR A CE2 1 
ATOM   158  C CZ  . TYR A 1 82   ? 105.719 83.130  91.869  1.00 53.72  ? 41   TYR A CZ  1 
ATOM   159  O OH  . TYR A 1 82   ? 105.133 83.431  90.663  1.00 53.72  ? 41   TYR A OH  1 
ATOM   160  N N   . VAL A 1 83   ? 109.241 82.438  98.281  1.00 47.57  ? 42   VAL A N   1 
ATOM   161  C CA  . VAL A 1 83   ? 109.354 82.399  99.738  1.00 47.57  ? 42   VAL A CA  1 
ATOM   162  C C   . VAL A 1 83   ? 109.913 83.717  100.259 1.00 47.57  ? 42   VAL A C   1 
ATOM   163  O O   . VAL A 1 83   ? 109.425 84.273  101.252 1.00 47.57  ? 42   VAL A O   1 
ATOM   164  C CB  . VAL A 1 83   ? 110.220 81.207  100.177 1.00 47.57  ? 42   VAL A CB  1 
ATOM   165  C CG1 . VAL A 1 83   ? 110.494 81.270  101.666 1.00 47.57  ? 42   VAL A CG1 1 
ATOM   166  C CG2 . VAL A 1 83   ? 109.539 79.904  99.819  1.00 47.57  ? 42   VAL A CG2 1 
ATOM   167  N N   . LEU A 1 84   ? 110.953 84.230  99.598  1.00 48.62  ? 43   LEU A N   1 
ATOM   168  C CA  . LEU A 1 84   ? 111.555 85.490  100.019 1.00 48.62  ? 43   LEU A CA  1 
ATOM   169  C C   . LEU A 1 84   ? 110.564 86.639  99.907  1.00 48.62  ? 43   LEU A C   1 
ATOM   170  O O   . LEU A 1 84   ? 110.490 87.493  100.792 1.00 48.62  ? 43   LEU A O   1 
ATOM   171  C CB  . LEU A 1 84   ? 112.801 85.782  99.186  1.00 48.62  ? 43   LEU A CB  1 
ATOM   172  C CG  . LEU A 1 84   ? 114.009 84.881  99.413  1.00 48.62  ? 43   LEU A CG  1 
ATOM   173  C CD1 . LEU A 1 84   ? 115.095 85.230  98.420  1.00 48.62  ? 43   LEU A CD1 1 
ATOM   174  C CD2 . LEU A 1 84   ? 114.511 85.024  100.833 1.00 48.62  ? 43   LEU A CD2 1 
ATOM   175  N N   . MET A 1 85   ? 109.798 86.680  98.817  1.00 48.40  ? 44   MET A N   1 
ATOM   176  C CA  . MET A 1 85   ? 108.819 87.745  98.647  1.00 48.40  ? 44   MET A CA  1 
ATOM   177  C C   . MET A 1 85   ? 107.738 87.666  99.715  1.00 48.40  ? 44   MET A C   1 
ATOM   178  O O   . MET A 1 85   ? 107.317 88.689  100.260 1.00 48.40  ? 44   MET A O   1 
ATOM   179  C CB  . MET A 1 85   ? 108.211 87.682  97.247  1.00 48.40  ? 44   MET A CB  1 
ATOM   180  C CG  . MET A 1 85   ? 109.081 88.322  96.177  1.00 48.40  ? 44   MET A CG  1 
ATOM   181  S SD  . MET A 1 85   ? 108.175 88.761  94.684  1.00 48.40  ? 44   MET A SD  1 
ATOM   182  C CE  . MET A 1 85   ? 107.363 87.211  94.314  1.00 48.40  ? 44   MET A CE  1 
ATOM   183  N N   . GLY A 1 86   ? 107.286 86.454  100.041 1.00 45.42  ? 45   GLY A N   1 
ATOM   184  C CA  . GLY A 1 86   ? 106.281 86.316  101.086 1.00 45.42  ? 45   GLY A CA  1 
ATOM   185  C C   . GLY A 1 86   ? 106.789 86.753  102.447 1.00 45.42  ? 45   GLY A C   1 
ATOM   186  O O   . GLY A 1 86   ? 106.110 87.487  103.174 1.00 45.42  ? 45   GLY A O   1 
ATOM   187  N N   . ILE A 1 87   ? 107.992 86.307  102.811 1.00 43.91  ? 46   ILE A N   1 
ATOM   188  C CA  . ILE A 1 87   ? 108.561 86.676  104.106 1.00 43.91  ? 46   ILE A CA  1 
ATOM   189  C C   . ILE A 1 87   ? 108.807 88.177  104.171 1.00 43.91  ? 46   ILE A C   1 
ATOM   190  O O   . ILE A 1 87   ? 108.527 88.826  105.186 1.00 43.91  ? 46   ILE A O   1 
ATOM   191  C CB  . ILE A 1 87   ? 109.848 85.879  104.378 1.00 43.91  ? 46   ILE A CB  1 
ATOM   192  C CG1 . ILE A 1 87   ? 109.529 84.393  104.527 1.00 43.91  ? 46   ILE A CG1 1 
ATOM   193  C CG2 . ILE A 1 87   ? 110.546 86.400  105.615 1.00 43.91  ? 46   ILE A CG2 1 
ATOM   194  C CD1 . ILE A 1 87   ? 110.749 83.527  104.721 1.00 43.91  ? 46   ILE A CD1 1 
ATOM   195  N N   . GLY A 1 88   ? 109.332 88.752  103.091 1.00 42.56  ? 47   GLY A N   1 
ATOM   196  C CA  . GLY A 1 88   ? 109.542 90.188  103.058 1.00 42.56  ? 47   GLY A CA  1 
ATOM   197  C C   . GLY A 1 88   ? 108.247 90.968  103.141 1.00 42.56  ? 47   GLY A C   1 
ATOM   198  O O   . GLY A 1 88   ? 108.190 92.020  103.773 1.00 42.56  ? 47   GLY A O   1 
ATOM   199  N N   . SER A 1 89   ? 107.188 90.465  102.505 1.00 42.71  ? 48   SER A N   1 
ATOM   200  C CA  . SER A 1 89   ? 105.901 91.147  102.561 1.00 42.71  ? 48   SER A CA  1 
ATOM   201  C C   . SER A 1 89   ? 105.327 91.116  103.972 1.00 42.71  ? 48   SER A C   1 
ATOM   202  O O   . SER A 1 89   ? 104.800 92.122  104.462 1.00 42.71  ? 48   SER A O   1 
ATOM   203  C CB  . SER A 1 89   ? 104.931 90.508  101.569 1.00 42.71  ? 48   SER A CB  1 
ATOM   204  O OG  . SER A 1 89   ? 103.660 91.122  101.641 1.00 42.71  ? 48   SER A OG  1 
ATOM   205  N N   . VAL A 1 90   ? 105.421 89.968  104.642 1.00 40.80  ? 49   VAL A N   1 
ATOM   206  C CA  . VAL A 1 90   ? 104.949 89.881  106.022 1.00 40.80  ? 49   VAL A CA  1 
ATOM   207  C C   . VAL A 1 90   ? 105.756 90.814  106.917 1.00 40.80  ? 49   VAL A C   1 
ATOM   208  O O   . VAL A 1 90   ? 105.202 91.532  107.762 1.00 40.80  ? 49   VAL A O   1 
ATOM   209  C CB  . VAL A 1 90   ? 105.007 88.428  106.521 1.00 40.80  ? 49   VAL A CB  1 
ATOM   210  C CG1 . VAL A 1 90   ? 104.797 88.378  108.019 1.00 40.80  ? 49   VAL A CG1 1 
ATOM   211  C CG2 . VAL A 1 90   ? 103.959 87.593  105.815 1.00 40.80  ? 49   VAL A CG2 1 
ATOM   212  N N   . GLY A 1 91   ? 107.078 90.820  106.742 1.00 39.68  ? 50   GLY A N   1 
ATOM   213  C CA  . GLY A 1 91   ? 107.914 91.714  107.525 1.00 39.68  ? 50   GLY A CA  1 
ATOM   214  C C   . GLY A 1 91   ? 107.582 93.172  107.287 1.00 39.68  ? 50   GLY A C   1 
ATOM   215  O O   . GLY A 1 91   ? 107.550 93.973  108.221 1.00 39.68  ? 50   GLY A O   1 
ATOM   216  N N   . ALA A 1 92   ? 107.326 93.537  106.031 1.00 39.32  ? 51   ALA A N   1 
ATOM   217  C CA  . ALA A 1 92   ? 106.975 94.915  105.711 1.00 39.32  ? 51   ALA A CA  1 
ATOM   218  C C   . ALA A 1 92   ? 105.645 95.300  106.338 1.00 39.32  ? 51   ALA A C   1 
ATOM   219  O O   . ALA A 1 92   ? 105.493 96.407  106.864 1.00 39.32  ? 51   ALA A O   1 
ATOM   220  C CB  . ALA A 1 92   ? 106.934 95.106  104.196 1.00 39.32  ? 51   ALA A CB  1 
ATOM   221  N N   . PHE A 1 93   ? 104.666 94.397  106.295 1.00 39.14  ? 52   PHE A N   1 
ATOM   222  C CA  . PHE A 1 93   ? 103.375 94.682  106.914 1.00 39.14  ? 52   PHE A CA  1 
ATOM   223  C C   . PHE A 1 93   ? 103.523 94.901  108.413 1.00 39.14  ? 52   PHE A C   1 
ATOM   224  O O   . PHE A 1 93   ? 102.974 95.859  108.971 1.00 39.14  ? 52   PHE A O   1 
ATOM   225  C CB  . PHE A 1 93   ? 102.396 93.546  106.638 1.00 39.14  ? 52   PHE A CB  1 
ATOM   226  C CG  . PHE A 1 93   ? 101.013 93.810  107.144 1.00 39.14  ? 52   PHE A CG  1 
ATOM   227  C CD1 . PHE A 1 93   ? 100.201 94.741  106.525 1.00 39.14  ? 52   PHE A CD1 1 
ATOM   228  C CD2 . PHE A 1 93   ? 100.529 93.139  108.251 1.00 39.14  ? 52   PHE A CD2 1 
ATOM   229  C CE1 . PHE A 1 93   ? 98.927  94.987  106.993 1.00 39.14  ? 52   PHE A CE1 1 
ATOM   230  C CE2 . PHE A 1 93   ? 99.257  93.383  108.724 1.00 39.14  ? 52   PHE A CE2 1 
ATOM   231  C CZ  . PHE A 1 93   ? 98.455  94.308  108.094 1.00 39.14  ? 52   PHE A CZ  1 
ATOM   232  N N   . VAL A 1 94   ? 104.268 94.020  109.084 1.00 40.59  ? 53   VAL A N   1 
ATOM   233  C CA  . VAL A 1 94   ? 104.445 94.155  110.527 1.00 40.59  ? 53   VAL A CA  1 
ATOM   234  C C   . VAL A 1 94   ? 105.196 95.440  110.858 1.00 40.59  ? 53   VAL A C   1 
ATOM   235  O O   . VAL A 1 94   ? 104.842 96.161  111.799 1.00 40.59  ? 53   VAL A O   1 
ATOM   236  C CB  . VAL A 1 94   ? 105.158 92.916  111.096 1.00 40.59  ? 53   VAL A CB  1 
ATOM   237  C CG1 . VAL A 1 94   ? 105.547 93.144  112.538 1.00 40.59  ? 53   VAL A CG1 1 
ATOM   238  C CG2 . VAL A 1 94   ? 104.262 91.703  110.980 1.00 40.59  ? 53   VAL A CG2 1 
ATOM   239  N N   . HIS A 1 95   ? 106.244 95.743  110.091 1.00 39.90  ? 54   HIS A N   1 
ATOM   240  C CA  . HIS A 1 95   ? 107.022 96.955  110.324 1.00 39.90  ? 54   HIS A CA  1 
ATOM   241  C C   . HIS A 1 95   ? 106.166 98.199  110.140 1.00 39.90  ? 54   HIS A C   1 
ATOM   242  O O   . HIS A 1 95   ? 106.295 99.173  110.889 1.00 39.90  ? 54   HIS A O   1 
ATOM   243  C CB  . HIS A 1 95   ? 108.225 96.978  109.384 1.00 39.90  ? 54   HIS A CB  1 
ATOM   244  C CG  . HIS A 1 95   ? 109.194 98.080  109.666 1.00 39.90  ? 54   HIS A CG  1 
ATOM   245  N ND1 . HIS A 1 95   ? 109.564 99.003  108.713 1.00 39.90  ? 54   HIS A ND1 1 
ATOM   246  C CD2 . HIS A 1 95   ? 109.872 98.406  110.789 1.00 39.90  ? 54   HIS A CD2 1 
ATOM   247  C CE1 . HIS A 1 95   ? 110.429 99.850  109.237 1.00 39.90  ? 54   HIS A CE1 1 
ATOM   248  N NE2 . HIS A 1 95   ? 110.632 99.512  110.497 1.00 39.90  ? 54   HIS A NE2 1 
ATOM   249  N N   . GLY A 1 96   ? 105.290 98.190  109.137 1.00 42.91  ? 55   GLY A N   1 
ATOM   250  C CA  . GLY A 1 96   ? 104.399 99.318  108.942 1.00 42.91  ? 55   GLY A CA  1 
ATOM   251  C C   . GLY A 1 96   ? 103.383 99.463  110.056 1.00 42.91  ? 55   GLY A C   1 
ATOM   252  O O   . GLY A 1 96   ? 103.092 100.574 110.500 1.00 42.91  ? 55   GLY A O   1 
ATOM   253  N N   . CYS A 1 97   ? 102.832 98.342  110.523 1.00 45.76  ? 56   CYS A N   1 
ATOM   254  C CA  . CYS A 1 97   ? 101.770 98.411  111.520 1.00 45.76  ? 56   CYS A CA  1 
ATOM   255  C C   . CYS A 1 97   ? 102.297 98.751  112.908 1.00 45.76  ? 56   CYS A C   1 
ATOM   256  O O   . CYS A 1 97   ? 101.567 99.337  113.713 1.00 45.76  ? 56   CYS A O   1 
ATOM   257  C CB  . CYS A 1 97   ? 101.004 97.091  111.568 1.00 45.76  ? 56   CYS A CB  1 
ATOM   258  S SG  . CYS A 1 97   ? 100.068 96.717  110.077 1.00 45.76  ? 56   CYS A SG  1 
ATOM   259  N N   . SER A 1 98   ? 103.548 98.404  113.213 1.00 47.66  ? 57   SER A N   1 
ATOM   260  C CA  . SER A 1 98   ? 103.993 98.457  114.604 1.00 47.66  ? 57   SER A CA  1 
ATOM   261  C C   . SER A 1 98   ? 104.267 99.881  115.078 1.00 47.66  ? 57   SER A C   1 
ATOM   262  O O   . SER A 1 98   ? 104.527 100.101 116.265 1.00 47.66  ? 57   SER A O   1 
ATOM   263  C CB  . SER A 1 98   ? 105.228 97.581  114.792 1.00 47.66  ? 57   SER A CB  1 
ATOM   264  O OG  . SER A 1 98   ? 104.926 96.221  114.545 1.00 47.66  ? 57   SER A OG  1 
ATOM   265  N N   . LEU A 1 99   ? 104.237 100.861 114.175 1.00 45.25  ? 58   LEU A N   1 
ATOM   266  C CA  . LEU A 1 99   ? 104.450 102.245 114.602 1.00 45.25  ? 58   LEU A CA  1 
ATOM   267  C C   . LEU A 1 99   ? 103.204 102.836 115.260 1.00 45.25  ? 58   LEU A C   1 
ATOM   268  O O   . LEU A 1 99   ? 103.301 103.341 116.395 1.00 45.25  ? 58   LEU A O   1 
ATOM   269  C CB  . LEU A 1 99   ? 104.942 103.066 113.407 1.00 45.25  ? 58   LEU A CB  1 
ATOM   270  C CG  . LEU A 1 99   ? 106.316 102.688 112.850 1.00 45.25  ? 58   LEU A CG  1 
ATOM   271  C CD1 . LEU A 1 99   ? 106.625 103.475 111.587 1.00 45.25  ? 58   LEU A CD1 1 
ATOM   272  C CD2 . LEU A 1 99   ? 107.400 102.896 113.885 1.00 45.25  ? 58   LEU A CD2 1 
ATOM   273  N N   . PRO A 1 100  ? 102.023 102.813 114.631 1.00 42.65  ? 59   PRO A N   1 
ATOM   274  C CA  . PRO A 1 100  ? 100.819 103.247 115.354 1.00 42.65  ? 59   PRO A CA  1 
ATOM   275  C C   . PRO A 1 100  ? 100.516 102.403 116.578 1.00 42.65  ? 59   PRO A C   1 
ATOM   276  O O   . PRO A 1 100  ? 99.915  102.909 117.533 1.00 42.65  ? 59   PRO A O   1 
ATOM   277  C CB  . PRO A 1 100  ? 99.719  103.130 114.295 1.00 42.65  ? 59   PRO A CB  1 
ATOM   278  C CG  . PRO A 1 100  ? 100.433 103.236 113.009 1.00 42.65  ? 59   PRO A CG  1 
ATOM   279  C CD  . PRO A 1 100  ? 101.712 102.520 113.221 1.00 42.65  ? 59   PRO A CD  1 
ATOM   280  N N   . LEU A 1 101  ? 100.904 101.126 116.584 1.00 39.64  ? 60   LEU A N   1 
ATOM   281  C CA  . LEU A 1 101  ? 100.784 100.337 117.805 1.00 39.64  ? 60   LEU A CA  1 
ATOM   282  C C   . LEU A 1 101  ? 101.647 100.915 118.915 1.00 39.64  ? 60   LEU A C   1 
ATOM   283  O O   . LEU A 1 101  ? 101.229 100.956 120.079 1.00 39.64  ? 60   LEU A O   1 
ATOM   284  C CB  . LEU A 1 101  ? 101.152 98.878  117.544 1.00 39.64  ? 60   LEU A CB  1 
ATOM   285  C CG  . LEU A 1 101  ? 100.029 97.933  117.117 1.00 39.64  ? 60   LEU A CG  1 
ATOM   286  C CD1 . LEU A 1 101  ? 99.028  97.805  118.247 1.00 39.64  ? 60   LEU A CD1 1 
ATOM   287  C CD2 . LEU A 1 101  ? 99.336  98.397  115.851 1.00 39.64  ? 60   LEU A CD2 1 
ATOM   288  N N   . PHE A 1 102  ? 102.855 101.369 118.580 1.00 40.17  ? 61   PHE A N   1 
ATOM   289  C CA  . PHE A 1 102  ? 103.674 102.029 119.588 1.00 40.17  ? 61   PHE A CA  1 
ATOM   290  C C   . PHE A 1 102  ? 103.010 103.304 120.080 1.00 40.17  ? 61   PHE A C   1 
ATOM   291  O O   . PHE A 1 102  ? 103.075 103.623 121.270 1.00 40.17  ? 61   PHE A O   1 
ATOM   292  C CB  . PHE A 1 102  ? 105.062 102.351 119.051 1.00 40.17  ? 61   PHE A CB  1 
ATOM   293  C CG  . PHE A 1 102  ? 105.812 103.316 119.914 1.00 40.17  ? 61   PHE A CG  1 
ATOM   294  C CD1 . PHE A 1 102  ? 106.254 102.938 121.167 1.00 40.17  ? 61   PHE A CD1 1 
ATOM   295  C CD2 . PHE A 1 102  ? 106.037 104.614 119.496 1.00 40.17  ? 61   PHE A CD2 1 
ATOM   296  C CE1 . PHE A 1 102  ? 106.930 103.825 121.974 1.00 40.17  ? 61   PHE A CE1 1 
ATOM   297  C CE2 . PHE A 1 102  ? 106.710 105.505 120.300 1.00 40.17  ? 61   PHE A CE2 1 
ATOM   298  C CZ  . PHE A 1 102  ? 107.156 105.110 121.540 1.00 40.17  ? 61   PHE A CZ  1 
ATOM   299  N N   . LEU A 1 103  ? 102.383 104.061 119.177 1.00 39.16  ? 62   LEU A N   1 
ATOM   300  C CA  . LEU A 1 103  ? 101.682 105.265 119.619 1.00 39.16  ? 62   LEU A CA  1 
ATOM   301  C C   . LEU A 1 103  ? 100.538 104.928 120.568 1.00 39.16  ? 62   LEU A C   1 
ATOM   302  O O   . LEU A 1 103  ? 100.327 105.620 121.571 1.00 39.16  ? 62   LEU A O   1 
ATOM   303  C CB  . LEU A 1 103  ? 101.172 106.054 118.417 1.00 39.16  ? 62   LEU A CB  1 
ATOM   304  C CG  . LEU A 1 103  ? 102.270 106.712 117.588 1.00 39.16  ? 62   LEU A CG  1 
ATOM   305  C CD1 . LEU A 1 103  ? 101.675 107.534 116.473 1.00 39.16  ? 62   LEU A CD1 1 
ATOM   306  C CD2 . LEU A 1 103  ? 103.135 107.576 118.480 1.00 39.16  ? 62   LEU A CD2 1 
ATOM   307  N N   . ARG A 1 104  ? 99.790  103.866 120.272 1.00 40.43  ? 63   ARG A N   1 
ATOM   308  C CA  . ARG A 1 104  ? 98.702  103.448 121.153 1.00 40.43  ? 63   ARG A CA  1 
ATOM   309  C C   . ARG A 1 104  ? 99.229  103.026 122.521 1.00 40.43  ? 63   ARG A C   1 
ATOM   310  O O   . ARG A 1 104  ? 98.650  103.368 123.561 1.00 40.43  ? 63   ARG A O   1 
ATOM   311  C CB  . ARG A 1 104  ? 97.921  102.310 120.499 1.00 40.43  ? 63   ARG A CB  1 
ATOM   312  C CG  . ARG A 1 104  ? 96.717  101.835 121.280 1.00 40.43  ? 63   ARG A CG  1 
ATOM   313  C CD  . ARG A 1 104  ? 95.792  102.981 121.621 1.00 40.43  ? 63   ARG A CD  1 
ATOM   314  N NE  . ARG A 1 104  ? 94.427  102.526 121.852 1.00 40.43  ? 63   ARG A NE  1 
ATOM   315  C CZ  . ARG A 1 104  ? 93.823  102.533 123.031 1.00 40.43  ? 63   ARG A CZ  1 
ATOM   316  N NH1 . ARG A 1 104  ? 94.448  102.932 124.125 1.00 40.43  ? 63   ARG A NH1 1 
ATOM   317  N NH2 . ARG A 1 104  ? 92.561  102.125 123.115 1.00 40.43  ? 63   ARG A NH2 1 
ATOM   318  N N   . PHE A 1 105  ? 100.331 102.277 122.539 1.00 39.50  ? 64   PHE A N   1 
ATOM   319  C CA  . PHE A 1 105  ? 100.907 101.850 123.810 1.00 39.50  ? 64   PHE A CA  1 
ATOM   320  C C   . PHE A 1 105  ? 101.436 103.040 124.600 1.00 39.50  ? 64   PHE A C   1 
ATOM   321  O O   . PHE A 1 105  ? 101.323 103.079 125.829 1.00 39.50  ? 64   PHE A O   1 
ATOM   322  C CB  . PHE A 1 105  ? 102.014 100.828 123.569 1.00 39.50  ? 64   PHE A CB  1 
ATOM   323  C CG  . PHE A 1 105  ? 101.513 99.486  123.124 1.00 39.50  ? 64   PHE A CG  1 
ATOM   324  C CD1 . PHE A 1 105  ? 100.163 99.190  123.157 1.00 39.50  ? 64   PHE A CD1 1 
ATOM   325  C CD2 . PHE A 1 105  ? 102.389 98.525  122.664 1.00 39.50  ? 64   PHE A CD2 1 
ATOM   326  C CE1 . PHE A 1 105  ? 99.700  97.961  122.746 1.00 39.50  ? 64   PHE A CE1 1 
ATOM   327  C CE2 . PHE A 1 105  ? 101.931 97.295  122.251 1.00 39.50  ? 64   PHE A CE2 1 
ATOM   328  C CZ  . PHE A 1 105  ? 100.585 97.012  122.292 1.00 39.50  ? 64   PHE A CZ  1 
ATOM   329  N N   . PHE A 1 106  ? 102.016 104.022 123.910 1.00 39.30  ? 65   PHE A N   1 
ATOM   330  C CA  . PHE A 1 106  ? 102.456 105.242 124.575 1.00 39.30  ? 65   PHE A CA  1 
ATOM   331  C C   . PHE A 1 106  ? 101.277 105.990 125.178 1.00 39.30  ? 65   PHE A C   1 
ATOM   332  O O   . PHE A 1 106  ? 101.369 106.526 126.287 1.00 39.30  ? 65   PHE A O   1 
ATOM   333  C CB  . PHE A 1 106  ? 103.205 106.133 123.590 1.00 39.30  ? 65   PHE A CB  1 
ATOM   334  C CG  . PHE A 1 106  ? 103.687 107.416 124.187 1.00 39.30  ? 65   PHE A CG  1 
ATOM   335  C CD1 . PHE A 1 106  ? 104.760 107.430 125.053 1.00 39.30  ? 65   PHE A CD1 1 
ATOM   336  C CD2 . PHE A 1 106  ? 103.054 108.608 123.892 1.00 39.30  ? 65   PHE A CD2 1 
ATOM   337  C CE1 . PHE A 1 106  ? 105.203 108.609 125.607 1.00 39.30  ? 65   PHE A CE1 1 
ATOM   338  C CE2 . PHE A 1 106  ? 103.488 109.790 124.446 1.00 39.30  ? 65   PHE A CE2 1 
ATOM   339  C CZ  . PHE A 1 106  ? 104.567 109.791 125.302 1.00 39.30  ? 65   PHE A CZ  1 
ATOM   340  N N   . ALA A 1 107  ? 100.162 106.051 124.449 1.00 41.39  ? 66   ALA A N   1 
ATOM   341  C CA  . ALA A 1 107  ? 98.967  106.696 124.981 1.00 41.39  ? 66   ALA A CA  1 
ATOM   342  C C   . ALA A 1 107  ? 98.493  106.002 126.246 1.00 41.39  ? 66   ALA A C   1 
ATOM   343  O O   . ALA A 1 107  ? 98.149  106.656 127.235 1.00 41.39  ? 66   ALA A O   1 
ATOM   344  C CB  . ALA A 1 107  ? 97.858  106.699 123.933 1.00 41.39  ? 66   ALA A CB  1 
ATOM   345  N N   . ASP A 1 108  ? 98.470  104.669 126.233 1.00 41.12  ? 67   ASP A N   1 
ATOM   346  C CA  . ASP A 1 108  ? 98.052  103.932 127.422 1.00 41.12  ? 67   ASP A CA  1 
ATOM   347  C C   . ASP A 1 108  ? 99.003  104.179 128.588 1.00 41.12  ? 67   ASP A C   1 
ATOM   348  O O   . ASP A 1 108  ? 98.567  104.369 129.730 1.00 41.12  ? 67   ASP A O   1 
ATOM   349  C CB  . ASP A 1 108  ? 97.953  102.441 127.110 1.00 41.12  ? 67   ASP A CB  1 
ATOM   350  C CG  . ASP A 1 108  ? 96.829  102.121 126.152 1.00 41.12  ? 67   ASP A CG  1 
ATOM   351  O OD1 . ASP A 1 108  ? 96.067  103.046 125.802 1.00 41.12  ? 67   ASP A OD1 1 
ATOM   352  O OD2 . ASP A 1 108  ? 96.703  100.947 125.749 1.00 41.12  ? 67   ASP A OD2 1 
ATOM   353  N N   . LEU A 1 109  ? 100.311 104.177 128.319 1.00 41.26  ? 68   LEU A N   1 
ATOM   354  C CA  . LEU A 1 109  ? 101.282 104.405 129.383 1.00 41.26  ? 68   LEU A CA  1 
ATOM   355  C C   . LEU A 1 109  ? 101.105 105.786 129.992 1.00 41.26  ? 68   LEU A C   1 
ATOM   356  O O   . LEU A 1 109  ? 101.100 105.941 131.216 1.00 41.26  ? 68   LEU A O   1 
ATOM   357  C CB  . LEU A 1 109  ? 102.704 104.238 128.848 1.00 41.26  ? 68   LEU A CB  1 
ATOM   358  C CG  . LEU A 1 109  ? 103.821 103.945 129.855 1.00 41.26  ? 68   LEU A CG  1 
ATOM   359  C CD1 . LEU A 1 109  ? 105.039 103.390 129.143 1.00 41.26  ? 68   LEU A CD1 1 
ATOM   360  C CD2 . LEU A 1 109  ? 104.207 105.162 130.673 1.00 41.26  ? 68   LEU A CD2 1 
ATOM   361  N N   . VAL A 1 110  ? 100.965 106.806 129.147 1.00 42.65  ? 69   VAL A N   1 
ATOM   362  C CA  . VAL A 1 110  ? 100.807 108.168 129.644 1.00 42.65  ? 69   VAL A CA  1 
ATOM   363  C C   . VAL A 1 110  ? 99.508  108.305 130.421 1.00 42.65  ? 69   VAL A C   1 
ATOM   364  O O   . VAL A 1 110  ? 99.464  108.952 131.473 1.00 42.65  ? 69   VAL A O   1 
ATOM   365  C CB  . VAL A 1 110  ? 100.887 109.170 128.479 1.00 42.65  ? 69   VAL A CB  1 
ATOM   366  C CG1 . VAL A 1 110  ? 100.403 110.534 128.918 1.00 42.65  ? 69   VAL A CG1 1 
ATOM   367  C CG2 . VAL A 1 110  ? 102.307 109.256 127.973 1.00 42.65  ? 69   VAL A CG2 1 
ATOM   368  N N   . ASN A 1 111  ? 98.431  107.696 129.924 1.00 41.78  ? 70   ASN A N   1 
ATOM   369  C CA  . ASN A 1 111  ? 97.151  107.788 130.614 1.00 41.78  ? 70   ASN A CA  1 
ATOM   370  C C   . ASN A 1 111  ? 97.223  107.153 131.994 1.00 41.78  ? 70   ASN A C   1 
ATOM   371  O O   . ASN A 1 111  ? 96.735  107.724 132.974 1.00 41.78  ? 70   ASN A O   1 
ATOM   372  C CB  . ASN A 1 111  ? 96.057  107.132 129.780 1.00 41.78  ? 70   ASN A CB  1 
ATOM   373  C CG  . ASN A 1 111  ? 94.716  107.165 130.463 1.00 41.78  ? 70   ASN A CG  1 
ATOM   374  O OD1 . ASN A 1 111  ? 94.199  108.233 130.780 1.00 41.78  ? 70   ASN A OD1 1 
ATOM   375  N ND2 . ASN A 1 111  ? 94.144  105.996 130.699 1.00 41.78  ? 70   ASN A ND2 1 
ATOM   376  N N   . SER A 1 112  ? 97.837  105.973 132.097 1.00 46.87  ? 71   SER A N   1 
ATOM   377  C CA  . SER A 1 112  ? 97.995  105.350 133.409 1.00 46.87  ? 71   SER A CA  1 
ATOM   378  C C   . SER A 1 112  ? 98.877  106.197 134.315 1.00 46.87  ? 71   SER A C   1 
ATOM   379  O O   . SER A 1 112  ? 98.535  106.447 135.479 1.00 46.87  ? 71   SER A O   1 
ATOM   380  C CB  . SER A 1 112  ? 98.584  103.951 133.254 1.00 46.87  ? 71   SER A CB  1 
ATOM   381  O OG  . SER A 1 112  ? 97.745  103.135 132.459 1.00 46.87  ? 71   SER A OG  1 
ATOM   382  N N   . PHE A 1 113  ? 99.998  106.675 133.780 1.00 45.98  ? 72   PHE A N   1 
ATOM   383  C CA  . PHE A 1 113  ? 100.992 107.390 134.570 1.00 45.98  ? 72   PHE A CA  1 
ATOM   384  C C   . PHE A 1 113  ? 100.456 108.733 135.050 1.00 45.98  ? 72   PHE A C   1 
ATOM   385  O O   . PHE A 1 113  ? 100.920 109.275 136.058 1.00 45.98  ? 72   PHE A O   1 
ATOM   386  C CB  . PHE A 1 113  ? 102.253 107.545 133.719 1.00 45.98  ? 72   PHE A CB  1 
ATOM   387  C CG  . PHE A 1 113  ? 103.352 108.323 134.362 1.00 45.98  ? 72   PHE A CG  1 
ATOM   388  C CD1 . PHE A 1 113  ? 103.807 108.000 135.620 1.00 45.98  ? 72   PHE A CD1 1 
ATOM   389  C CD2 . PHE A 1 113  ? 103.984 109.334 133.668 1.00 45.98  ? 72   PHE A CD2 1 
ATOM   390  C CE1 . PHE A 1 113  ? 104.836 108.710 136.197 1.00 45.98  ? 72   PHE A CE1 1 
ATOM   391  C CE2 . PHE A 1 113  ? 105.013 110.040 134.236 1.00 45.98  ? 72   PHE A CE2 1 
ATOM   392  C CZ  . PHE A 1 113  ? 105.441 109.726 135.501 1.00 45.98  ? 72   PHE A CZ  1 
ATOM   393  N N   . GLY A 1 114  ? 99.472  109.280 134.346 1.00 51.97  ? 73   GLY A N   1 
ATOM   394  C CA  . GLY A 1 114  ? 98.878  110.537 134.748 1.00 51.97  ? 73   GLY A CA  1 
ATOM   395  C C   . GLY A 1 114  ? 97.638  110.384 135.601 1.00 51.97  ? 73   GLY A C   1 
ATOM   396  O O   . GLY A 1 114  ? 97.372  111.222 136.465 1.00 51.97  ? 73   GLY A O   1 
ATOM   397  N N   . SER A 1 115  ? 96.862  109.323 135.368 1.00 54.61  ? 74   SER A N   1 
ATOM   398  C CA  . SER A 1 115  ? 95.638  109.123 136.134 1.00 54.61  ? 74   SER A CA  1 
ATOM   399  C C   . SER A 1 115  ? 95.928  108.563 137.518 1.00 54.61  ? 74   SER A C   1 
ATOM   400  O O   . SER A 1 115  ? 95.224  108.885 138.481 1.00 54.61  ? 74   SER A O   1 
ATOM   401  C CB  . SER A 1 115  ? 94.690  108.200 135.373 1.00 54.61  ? 74   SER A CB  1 
ATOM   402  O OG  . SER A 1 115  ? 94.230  108.816 134.185 1.00 54.61  ? 74   SER A OG  1 
ATOM   403  N N   . ASN A 1 116  ? 96.964  107.731 137.650 1.00 61.01  ? 75   ASN A N   1 
ATOM   404  C CA  . ASN A 1 116  ? 97.227  107.044 138.907 1.00 61.01  ? 75   ASN A CA  1 
ATOM   405  C C   . ASN A 1 116  ? 98.211  107.790 139.794 1.00 61.01  ? 75   ASN A C   1 
ATOM   406  O O   . ASN A 1 116  ? 99.003  107.156 140.501 1.00 61.01  ? 75   ASN A O   1 
ATOM   407  C CB  . ASN A 1 116  ? 97.720  105.625 138.634 1.00 61.01  ? 75   ASN A CB  1 
ATOM   408  C CG  . ASN A 1 116  ? 96.740  104.822 137.812 1.00 61.01  ? 75   ASN A CG  1 
ATOM   409  O OD1 . ASN A 1 116  ? 95.529  104.993 137.930 1.00 61.01  ? 75   ASN A OD1 1 
ATOM   410  N ND2 . ASN A 1 116  ? 97.258  103.936 136.972 1.00 61.01  ? 75   ASN A ND2 1 
ATOM   411  N N   . SER A 1 117  ? 98.195  109.123 139.762 1.00 70.43  ? 76   SER A N   1 
ATOM   412  C CA  . SER A 1 117  ? 99.105  109.895 140.602 1.00 70.43  ? 76   SER A CA  1 
ATOM   413  C C   . SER A 1 117  ? 98.874  109.611 142.081 1.00 70.43  ? 76   SER A C   1 
ATOM   414  O O   . SER A 1 117  ? 99.832  109.493 142.855 1.00 70.43  ? 76   SER A O   1 
ATOM   415  C CB  . SER A 1 117  ? 98.942  111.386 140.317 1.00 70.43  ? 76   SER A CB  1 
ATOM   416  O OG  . SER A 1 117  ? 97.617  111.808 140.584 1.00 70.43  ? 76   SER A OG  1 
ATOM   417  N N   . ASN A 1 118  ? 97.609  109.506 142.496 1.00 70.69  ? 77   ASN A N   1 
ATOM   418  C CA  . ASN A 1 118  ? 97.311  109.236 143.900 1.00 70.69  ? 77   ASN A CA  1 
ATOM   419  C C   . ASN A 1 118  ? 97.710  107.815 144.289 1.00 70.69  ? 77   ASN A C   1 
ATOM   420  O O   . ASN A 1 118  ? 98.350  107.600 145.325 1.00 70.69  ? 77   ASN A O   1 
ATOM   421  C CB  . ASN A 1 118  ? 95.826  109.476 144.171 1.00 70.69  ? 77   ASN A CB  1 
ATOM   422  C CG  . ASN A 1 118  ? 94.933  108.829 143.135 1.00 70.69  ? 77   ASN A CG  1 
ATOM   423  O OD1 . ASN A 1 118  ? 95.017  109.138 141.947 1.00 70.69  ? 77   ASN A OD1 1 
ATOM   424  N ND2 . ASN A 1 118  ? 94.071  107.925 143.580 1.00 70.69  ? 77   ASN A ND2 1 
ATOM   425  N N   . ASN A 1 119  ? 97.343  106.831 143.470 1.00 67.26  ? 78   ASN A N   1 
ATOM   426  C CA  . ASN A 1 119  ? 97.668  105.430 143.739 1.00 67.26  ? 78   ASN A CA  1 
ATOM   427  C C   . ASN A 1 119  ? 99.001  105.119 143.074 1.00 67.26  ? 78   ASN A C   1 
ATOM   428  O O   . ASN A 1 119  ? 99.068  104.786 141.892 1.00 67.26  ? 78   ASN A O   1 
ATOM   429  C CB  . ASN A 1 119  ? 96.559  104.515 143.241 1.00 67.26  ? 78   ASN A CB  1 
ATOM   430  C CG  . ASN A 1 119  ? 96.678  103.107 143.784 1.00 67.26  ? 78   ASN A CG  1 
ATOM   431  O OD1 . ASN A 1 119  ? 97.617  102.788 144.511 1.00 67.26  ? 78   ASN A OD1 1 
ATOM   432  N ND2 . ASN A 1 119  ? 95.722  102.255 143.435 1.00 67.26  ? 78   ASN A ND2 1 
ATOM   433  N N   . VAL A 1 120  ? 100.077 105.219 143.854 1.00 62.21  ? 79   VAL A N   1 
ATOM   434  C CA  . VAL A 1 120  ? 101.426 105.109 143.298 1.00 62.21  ? 79   VAL A CA  1 
ATOM   435  C C   . VAL A 1 120  ? 101.683 103.708 142.756 1.00 62.21  ? 79   VAL A C   1 
ATOM   436  O O   . VAL A 1 120  ? 102.245 103.538 141.668 1.00 62.21  ? 79   VAL A O   1 
ATOM   437  C CB  . VAL A 1 120  ? 102.469 105.504 144.357 1.00 62.21  ? 79   VAL A CB  1 
ATOM   438  C CG1 . VAL A 1 120  ? 103.862 105.255 143.836 1.00 62.21  ? 79   VAL A CG1 1 
ATOM   439  C CG2 . VAL A 1 120  ? 102.302 106.960 144.739 1.00 62.21  ? 79   VAL A CG2 1 
ATOM   440  N N   . GLU A 1 121  ? 101.285 102.681 143.511 1.00 65.14  ? 80   GLU A N   1 
ATOM   441  C CA  . GLU A 1 121  ? 101.629 101.310 143.141 1.00 65.14  ? 80   GLU A CA  1 
ATOM   442  C C   . GLU A 1 121  ? 100.978 100.904 141.825 1.00 65.14  ? 80   GLU A C   1 
ATOM   443  O O   . GLU A 1 121  ? 101.602 100.236 140.988 1.00 65.14  ? 80   GLU A O   1 
ATOM   444  C CB  . GLU A 1 121  ? 101.230 100.352 144.261 1.00 65.14  ? 80   GLU A CB  1 
ATOM   445  C CG  . GLU A 1 121  ? 101.864 100.686 145.595 1.00 65.14  ? 80   GLU A CG  1 
ATOM   446  C CD  . GLU A 1 121  ? 103.360 100.904 145.484 1.00 65.14  ? 80   GLU A CD  1 
ATOM   447  O OE1 . GLU A 1 121  ? 104.071 99.963  145.076 1.00 65.14  ? 80   GLU A OE1 1 
ATOM   448  O OE2 . GLU A 1 121  ? 103.825 102.018 145.802 1.00 65.14  ? 80   GLU A OE2 1 
ATOM   449  N N   . LYS A 1 122  ? 99.714  101.283 141.629 1.00 62.79  ? 81   LYS A N   1 
ATOM   450  C CA  . LYS A 1 122  ? 99.048  100.990 140.365 1.00 62.79  ? 81   LYS A CA  1 
ATOM   451  C C   . LYS A 1 122  ? 99.770  101.665 139.208 1.00 62.79  ? 81   LYS A C   1 
ATOM   452  O O   . LYS A 1 122  ? 99.968  101.066 138.144 1.00 62.79  ? 81   LYS A O   1 
ATOM   453  C CB  . LYS A 1 122  ? 97.588  101.435 140.422 1.00 62.79  ? 81   LYS A CB  1 
ATOM   454  C CG  . LYS A 1 122  ? 96.816  101.149 139.146 1.00 62.79  ? 81   LYS A CG  1 
ATOM   455  C CD  . LYS A 1 122  ? 95.432  101.771 139.179 1.00 62.79  ? 81   LYS A CD  1 
ATOM   456  C CE  . LYS A 1 122  ? 94.623  101.256 140.354 1.00 62.79  ? 81   LYS A CE  1 
ATOM   457  N NZ  . LYS A 1 122  ? 93.290  101.914 140.435 1.00 62.79  ? 81   LYS A NZ  1 
ATOM   458  N N   . MET A 1 123  ? 100.179 102.920 139.405 1.00 59.24  ? 82   MET A N   1 
ATOM   459  C CA  . MET A 1 123  ? 100.923 103.628 138.372 1.00 59.24  ? 82   MET A CA  1 
ATOM   460  C C   . MET A 1 123  ? 102.213 102.895 138.040 1.00 59.24  ? 82   MET A C   1 
ATOM   461  O O   . MET A 1 123  ? 102.551 102.711 136.864 1.00 59.24  ? 82   MET A O   1 
ATOM   462  C CB  . MET A 1 123  ? 101.214 105.057 138.830 1.00 59.24  ? 82   MET A CB  1 
ATOM   463  C CG  . MET A 1 123  ? 102.152 105.828 137.926 1.00 59.24  ? 82   MET A CG  1 
ATOM   464  S SD  . MET A 1 123  ? 103.220 106.948 138.845 1.00 59.24  ? 82   MET A SD  1 
ATOM   465  C CE  . MET A 1 123  ? 104.248 105.784 139.723 1.00 59.24  ? 82   MET A CE  1 
ATOM   466  N N   . MET A 1 124  ? 102.938 102.448 139.065 1.00 60.22  ? 83   MET A N   1 
ATOM   467  C CA  . MET A 1 124  ? 104.206 101.769 138.832 1.00 60.22  ? 83   MET A CA  1 
ATOM   468  C C   . MET A 1 124  ? 104.004 100.474 138.056 1.00 60.22  ? 83   MET A C   1 
ATOM   469  O O   . MET A 1 124  ? 104.725 100.198 137.091 1.00 60.22  ? 83   MET A O   1 
ATOM   470  C CB  . MET A 1 124  ? 104.910 101.494 140.160 1.00 60.22  ? 83   MET A CB  1 
ATOM   471  C CG  . MET A 1 124  ? 105.779 102.636 140.645 1.00 60.22  ? 83   MET A CG  1 
ATOM   472  S SD  . MET A 1 124  ? 107.236 102.951 139.630 1.00 60.22  ? 83   MET A SD  1 
ATOM   473  C CE  . MET A 1 124  ? 107.711 101.291 139.153 1.00 60.22  ? 83   MET A CE  1 
ATOM   474  N N   . GLU A 1 125  ? 103.014 99.670  138.450 1.00 60.00  ? 84   GLU A N   1 
ATOM   475  C CA  . GLU A 1 125  ? 102.834 98.382  137.786 1.00 60.00  ? 84   GLU A CA  1 
ATOM   476  C C   . GLU A 1 125  ? 102.346 98.557  136.350 1.00 60.00  ? 84   GLU A C   1 
ATOM   477  O O   . GLU A 1 125  ? 102.792 97.840  135.443 1.00 60.00  ? 84   GLU A O   1 
ATOM   478  C CB  . GLU A 1 125  ? 101.886 97.489  138.589 1.00 60.00  ? 84   GLU A CB  1 
ATOM   479  C CG  . GLU A 1 125  ? 100.499 98.046  138.814 1.00 60.00  ? 84   GLU A CG  1 
ATOM   480  C CD  . GLU A 1 125  ? 99.676  97.186  139.748 1.00 60.00  ? 84   GLU A CD  1 
ATOM   481  O OE1 . GLU A 1 125  ? 99.458  95.999  139.427 1.00 60.00  ? 84   GLU A OE1 1 
ATOM   482  O OE2 . GLU A 1 125  ? 99.245  97.693  140.805 1.00 60.00  ? 84   GLU A OE2 1 
ATOM   483  N N   . GLU A 1 126  ? 101.444 99.515  136.112 1.00 54.01  ? 85   GLU A N   1 
ATOM   484  C CA  . GLU A 1 126  ? 100.986 99.743  134.746 1.00 54.01  ? 85   GLU A CA  1 
ATOM   485  C C   . GLU A 1 126  ? 102.108 100.286 133.868 1.00 54.01  ? 85   GLU A C   1 
ATOM   486  O O   . GLU A 1 126  ? 102.256 99.870  132.710 1.00 54.01  ? 85   GLU A O   1 
ATOM   487  C CB  . GLU A 1 126  ? 99.786  100.684 134.742 1.00 54.01  ? 85   GLU A CB  1 
ATOM   488  C CG  . GLU A 1 126  ? 98.582  100.118 135.462 1.00 54.01  ? 85   GLU A CG  1 
ATOM   489  C CD  . GLU A 1 126  ? 97.277  100.452 134.773 1.00 54.01  ? 85   GLU A CD  1 
ATOM   490  O OE1 . GLU A 1 126  ? 97.239  100.418 133.526 1.00 54.01  ? 85   GLU A OE1 1 
ATOM   491  O OE2 . GLU A 1 126  ? 96.290  100.746 135.477 1.00 54.01  ? 85   GLU A OE2 1 
ATOM   492  N N   . VAL A 1 127  ? 102.917 101.204 134.397 1.00 52.52  ? 86   VAL A N   1 
ATOM   493  C CA  . VAL A 1 127  ? 104.044 101.713 133.626 1.00 52.52  ? 86   VAL A CA  1 
ATOM   494  C C   . VAL A 1 127  ? 105.021 100.588 133.317 1.00 52.52  ? 86   VAL A C   1 
ATOM   495  O O   . VAL A 1 127  ? 105.595 100.531 132.224 1.00 52.52  ? 86   VAL A O   1 
ATOM   496  C CB  . VAL A 1 127  ? 104.722 102.873 134.374 1.00 52.52  ? 86   VAL A CB  1 
ATOM   497  C CG1 . VAL A 1 127  ? 106.121 103.101 133.842 1.00 52.52  ? 86   VAL A CG1 1 
ATOM   498  C CG2 . VAL A 1 127  ? 103.894 104.134 134.241 1.00 52.52  ? 86   VAL A CG2 1 
ATOM   499  N N   . LEU A 1 128  ? 105.218 99.669  134.263 1.00 52.14  ? 87   LEU A N   1 
ATOM   500  C CA  . LEU A 1 128  ? 106.109 98.542  134.012 1.00 52.14  ? 87   LEU A CA  1 
ATOM   501  C C   . LEU A 1 128  ? 105.580 97.657  132.889 1.00 52.14  ? 87   LEU A C   1 
ATOM   502  O O   . LEU A 1 128  ? 106.332 97.260  131.987 1.00 52.14  ? 87   LEU A O   1 
ATOM   503  C CB  . LEU A 1 128  ? 106.299 97.732  135.290 1.00 52.14  ? 87   LEU A CB  1 
ATOM   504  C CG  . LEU A 1 128  ? 107.209 96.516  135.143 1.00 52.14  ? 87   LEU A CG  1 
ATOM   505  C CD1 . LEU A 1 128  ? 108.648 96.958  134.960 1.00 52.14  ? 87   LEU A CD1 1 
ATOM   506  C CD2 . LEU A 1 128  ? 107.075 95.609  136.346 1.00 52.14  ? 87   LEU A CD2 1 
ATOM   507  N N   . LYS A 1 129  ? 104.284 97.336  132.923 1.00 47.81  ? 88   LYS A N   1 
ATOM   508  C CA  . LYS A 1 129  ? 103.740 96.471  131.878 1.00 47.81  ? 88   LYS A CA  1 
ATOM   509  C C   . LYS A 1 129  ? 103.822 97.146  130.514 1.00 47.81  ? 88   LYS A C   1 
ATOM   510  O O   . LYS A 1 129  ? 104.112 96.494  129.503 1.00 47.81  ? 88   LYS A O   1 
ATOM   511  C CB  . LYS A 1 129  ? 102.304 96.052  132.204 1.00 47.81  ? 88   LYS A CB  1 
ATOM   512  C CG  . LYS A 1 129  ? 101.236 97.079  131.902 1.00 47.81  ? 88   LYS A CG  1 
ATOM   513  C CD  . LYS A 1 129  ? 99.876  96.635  132.407 1.00 47.81  ? 88   LYS A CD  1 
ATOM   514  C CE  . LYS A 1 129  ? 99.293  95.541  131.538 1.00 47.81  ? 88   LYS A CE  1 
ATOM   515  N NZ  . LYS A 1 129  ? 98.992  96.032  130.169 1.00 47.81  ? 88   LYS A NZ  1 
ATOM   516  N N   . TYR A 1 130  ? 103.613 98.462  130.463 1.00 45.39  ? 89   TYR A N   1 
ATOM   517  C CA  . TYR A 1 130  ? 103.685 99.134  129.169 1.00 45.39  ? 89   TYR A CA  1 
ATOM   518  C C   . TYR A 1 130  ? 105.123 99.320  128.700 1.00 45.39  ? 89   TYR A C   1 
ATOM   519  O O   . TYR A 1 130  ? 105.377 99.346  127.493 1.00 45.39  ? 89   TYR A O   1 
ATOM   520  C CB  . TYR A 1 130  ? 102.936 100.458 129.228 1.00 45.39  ? 89   TYR A CB  1 
ATOM   521  C CG  . TYR A 1 130  ? 101.443 100.256 129.216 1.00 45.39  ? 89   TYR A CG  1 
ATOM   522  C CD1 . TYR A 1 130  ? 100.828 99.599  128.165 1.00 45.39  ? 89   TYR A CD1 1 
ATOM   523  C CD2 . TYR A 1 130  ? 100.655 100.692 130.265 1.00 45.39  ? 89   TYR A CD2 1 
ATOM   524  C CE1 . TYR A 1 130  ? 99.468  99.398  128.152 1.00 45.39  ? 89   TYR A CE1 1 
ATOM   525  C CE2 . TYR A 1 130  ? 99.292  100.494 130.261 1.00 45.39  ? 89   TYR A CE2 1 
ATOM   526  C CZ  . TYR A 1 130  ? 98.704  99.845  129.202 1.00 45.39  ? 89   TYR A CZ  1 
ATOM   527  O OH  . TYR A 1 130  ? 97.345  99.648  129.194 1.00 45.39  ? 89   TYR A OH  1 
ATOM   528  N N   . ALA A 1 131  ? 106.082 99.424  129.620 1.00 45.08  ? 90   ALA A N   1 
ATOM   529  C CA  . ALA A 1 131  ? 107.483 99.402  129.213 1.00 45.08  ? 90   ALA A CA  1 
ATOM   530  C C   . ALA A 1 131  ? 107.856 98.049  128.618 1.00 45.08  ? 90   ALA A C   1 
ATOM   531  O O   . ALA A 1 131  ? 108.608 97.972  127.636 1.00 45.08  ? 90   ALA A O   1 
ATOM   532  C CB  . ALA A 1 131  ? 108.382 99.737  130.401 1.00 45.08  ? 90   ALA A CB  1 
ATOM   533  N N   . LEU A 1 132  ? 107.340 96.969  129.204 1.00 44.05  ? 91   LEU A N   1 
ATOM   534  C CA  . LEU A 1 132  ? 107.545 95.654  128.605 1.00 44.05  ? 91   LEU A CA  1 
ATOM   535  C C   . LEU A 1 132  ? 106.910 95.581  127.223 1.00 44.05  ? 91   LEU A C   1 
ATOM   536  O O   . LEU A 1 132  ? 107.473 94.979  126.300 1.00 44.05  ? 91   LEU A O   1 
ATOM   537  C CB  . LEU A 1 132  ? 106.986 94.568  129.519 1.00 44.05  ? 91   LEU A CB  1 
ATOM   538  C CG  . LEU A 1 132  ? 107.636 94.504  130.898 1.00 44.05  ? 91   LEU A CG  1 
ATOM   539  C CD1 . LEU A 1 132  ? 107.181 93.266  131.644 1.00 44.05  ? 91   LEU A CD1 1 
ATOM   540  C CD2 . LEU A 1 132  ? 109.149 94.538  130.777 1.00 44.05  ? 91   LEU A CD2 1 
ATOM   541  N N   . TYR A 1 133  ? 105.735 96.191  127.059 1.00 41.27  ? 92   TYR A N   1 
ATOM   542  C CA  . TYR A 1 133  ? 105.130 96.268  125.732 1.00 41.27  ? 92   TYR A CA  1 
ATOM   543  C C   . TYR A 1 133  ? 106.023 97.032  124.762 1.00 41.27  ? 92   TYR A C   1 
ATOM   544  O O   . TYR A 1 133  ? 106.116 96.680  123.583 1.00 41.27  ? 92   TYR A O   1 
ATOM   545  C CB  . TYR A 1 133  ? 103.753 96.922  125.803 1.00 41.27  ? 92   TYR A CB  1 
ATOM   546  C CG  . TYR A 1 133  ? 102.662 96.034  126.350 1.00 41.27  ? 92   TYR A CG  1 
ATOM   547  C CD1 . TYR A 1 133  ? 102.942 94.762  126.821 1.00 41.27  ? 92   TYR A CD1 1 
ATOM   548  C CD2 . TYR A 1 133  ? 101.347 96.466  126.377 1.00 41.27  ? 92   TYR A CD2 1 
ATOM   549  C CE1 . TYR A 1 133  ? 101.943 93.954  127.317 1.00 41.27  ? 92   TYR A CE1 1 
ATOM   550  C CE2 . TYR A 1 133  ? 100.343 95.666  126.868 1.00 41.27  ? 92   TYR A CE2 1 
ATOM   551  C CZ  . TYR A 1 133  ? 100.644 94.412  127.337 1.00 41.27  ? 92   TYR A CZ  1 
ATOM   552  O OH  . TYR A 1 133  ? 99.641  93.612  127.827 1.00 41.27  ? 92   TYR A OH  1 
ATOM   553  N N   . PHE A 1 134  ? 106.670 98.098  125.236 1.00 44.98  ? 93   PHE A N   1 
ATOM   554  C CA  . PHE A 1 134  ? 107.592 98.843  124.382 1.00 44.98  ? 93   PHE A CA  1 
ATOM   555  C C   . PHE A 1 134  ? 108.754 97.969  123.936 1.00 44.98  ? 93   PHE A C   1 
ATOM   556  O O   . PHE A 1 134  ? 109.161 98.011  122.770 1.00 44.98  ? 93   PHE A O   1 
ATOM   557  C CB  . PHE A 1 134  ? 108.129 100.075 125.108 1.00 44.98  ? 93   PHE A CB  1 
ATOM   558  C CG  . PHE A 1 134  ? 107.154 101.206 125.199 1.00 44.98  ? 93   PHE A CG  1 
ATOM   559  C CD1 . PHE A 1 134  ? 105.874 101.084 124.697 1.00 44.98  ? 93   PHE A CD1 1 
ATOM   560  C CD2 . PHE A 1 134  ? 107.525 102.400 125.783 1.00 44.98  ? 93   PHE A CD2 1 
ATOM   561  C CE1 . PHE A 1 134  ? 104.985 102.128 124.788 1.00 44.98  ? 93   PHE A CE1 1 
ATOM   562  C CE2 . PHE A 1 134  ? 106.639 103.445 125.874 1.00 44.98  ? 93   PHE A CE2 1 
ATOM   563  C CZ  . PHE A 1 134  ? 105.368 103.310 125.375 1.00 44.98  ? 93   PHE A CZ  1 
ATOM   564  N N   . LEU A 1 135  ? 109.312 97.181  124.855 1.00 40.01  ? 94   LEU A N   1 
ATOM   565  C CA  . LEU A 1 135  ? 110.402 96.282  124.479 1.00 40.01  ? 94   LEU A CA  1 
ATOM   566  C C   . LEU A 1 135  ? 109.936 95.239  123.467 1.00 40.01  ? 94   LEU A C   1 
ATOM   567  O O   . LEU A 1 135  ? 110.660 94.914  122.517 1.00 40.01  ? 94   LEU A O   1 
ATOM   568  C CB  . LEU A 1 135  ? 110.984 95.606  125.717 1.00 40.01  ? 94   LEU A CB  1 
ATOM   569  C CG  . LEU A 1 135  ? 111.586 96.558  126.746 1.00 40.01  ? 94   LEU A CG  1 
ATOM   570  C CD1 . LEU A 1 135  ? 112.294 95.785  127.840 1.00 40.01  ? 94   LEU A CD1 1 
ATOM   571  C CD2 . LEU A 1 135  ? 112.542 97.511  126.065 1.00 40.01  ? 94   LEU A CD2 1 
ATOM   572  N N   . VAL A 1 136  ? 108.729 94.706  123.655 1.00 41.18  ? 95   VAL A N   1 
ATOM   573  C CA  . VAL A 1 136  ? 108.188 93.735  122.708 1.00 41.18  ? 95   VAL A CA  1 
ATOM   574  C C   . VAL A 1 136  ? 108.016 94.366  121.331 1.00 41.18  ? 95   VAL A C   1 
ATOM   575  O O   . VAL A 1 136  ? 108.341 93.754  120.306 1.00 41.18  ? 95   VAL A O   1 
ATOM   576  C CB  . VAL A 1 136  ? 106.864 93.158  123.237 1.00 41.18  ? 95   VAL A CB  1 
ATOM   577  C CG1 . VAL A 1 136  ? 106.152 92.378  122.152 1.00 41.18  ? 95   VAL A CG1 1 
ATOM   578  C CG2 . VAL A 1 136  ? 107.125 92.279  124.442 1.00 41.18  ? 95   VAL A CG2 1 
ATOM   579  N N   . VAL A 1 137  ? 107.499 95.595  121.285 1.00 41.39  ? 96   VAL A N   1 
ATOM   580  C CA  . VAL A 1 137  ? 107.314 96.280  120.010 1.00 41.39  ? 96   VAL A CA  1 
ATOM   581  C C   . VAL A 1 137  ? 108.660 96.548  119.352 1.00 41.39  ? 96   VAL A C   1 
ATOM   582  O O   . VAL A 1 137  ? 108.804 96.454  118.128 1.00 41.39  ? 96   VAL A O   1 
ATOM   583  C CB  . VAL A 1 137  ? 106.510 97.577  120.209 1.00 41.39  ? 96   VAL A CB  1 
ATOM   584  C CG1 . VAL A 1 137  ? 106.589 98.452  118.974 1.00 41.39  ? 96   VAL A CG1 1 
ATOM   585  C CG2 . VAL A 1 137  ? 105.068 97.251  120.520 1.00 41.39  ? 96   VAL A CG2 1 
ATOM   586  N N   . GLY A 1 138  ? 109.669 96.886  120.152 1.00 42.31  ? 97   GLY A N   1 
ATOM   587  C CA  . GLY A 1 138  ? 111.001 97.072  119.599 1.00 42.31  ? 97   GLY A CA  1 
ATOM   588  C C   . GLY A 1 138  ? 111.549 95.803  118.975 1.00 42.31  ? 97   GLY A C   1 
ATOM   589  O O   . GLY A 1 138  ? 112.125 95.829  117.886 1.00 42.31  ? 97   GLY A O   1 
ATOM   590  N N   . ALA A 1 139  ? 111.368 94.671  119.657 1.00 41.36  ? 98   ALA A N   1 
ATOM   591  C CA  . ALA A 1 139  ? 111.824 93.396  119.108 1.00 41.36  ? 98   ALA A CA  1 
ATOM   592  C C   . ALA A 1 139  ? 111.079 93.049  117.823 1.00 41.36  ? 98   ALA A C   1 
ATOM   593  O O   . ALA A 1 139  ? 111.671 92.547  116.859 1.00 41.36  ? 98   ALA A O   1 
ATOM   594  C CB  . ALA A 1 139  ? 111.655 92.289  120.145 1.00 41.36  ? 98   ALA A CB  1 
ATOM   595  N N   . ALA A 1 140  ? 109.768 93.300  117.799 1.00 40.13  ? 99   ALA A N   1 
ATOM   596  C CA  . ALA A 1 140  ? 108.985 93.036  116.596 1.00 40.13  ? 99   ALA A CA  1 
ATOM   597  C C   . ALA A 1 140  ? 109.445 93.910  115.438 1.00 40.13  ? 99   ALA A C   1 
ATOM   598  O O   . ALA A 1 140  ? 109.543 93.448  114.298 1.00 40.13  ? 99   ALA A O   1 
ATOM   599  C CB  . ALA A 1 140  ? 107.501 93.252  116.876 1.00 40.13  ? 99   ALA A CB  1 
ATOM   600  N N   . ILE A 1 141  ? 109.725 95.187  115.712 1.00 39.23  ? 100  ILE A N   1 
ATOM   601  C CA  . ILE A 1 141  ? 110.239 96.080  114.677 1.00 39.23  ? 100  ILE A CA  1 
ATOM   602  C C   . ILE A 1 141  ? 111.579 95.574  114.164 1.00 39.23  ? 100  ILE A C   1 
ATOM   603  O O   . ILE A 1 141  ? 111.836 95.565  112.956 1.00 39.23  ? 100  ILE A O   1 
ATOM   604  C CB  . ILE A 1 141  ? 110.354 97.518  115.216 1.00 39.23  ? 100  ILE A CB  1 
ATOM   605  C CG1 . ILE A 1 141  ? 108.981 98.176  115.297 1.00 39.23  ? 100  ILE A CG1 1 
ATOM   606  C CG2 . ILE A 1 141  ? 111.249 98.345  114.323 1.00 39.23  ? 100  ILE A CG2 1 
ATOM   607  C CD1 . ILE A 1 141  ? 108.426 98.551  113.954 1.00 39.23  ? 100  ILE A CD1 1 
ATOM   608  N N   . TRP A 1 142  ? 112.450 95.142  115.075 1.00 42.54  ? 101  TRP A N   1 
ATOM   609  C CA  . TRP A 1 142  ? 113.744 94.597  114.683 1.00 42.54  ? 101  TRP A CA  1 
ATOM   610  C C   . TRP A 1 142  ? 113.574 93.433  113.715 1.00 42.54  ? 101  TRP A C   1 
ATOM   611  O O   . TRP A 1 142  ? 114.119 93.440  112.603 1.00 42.54  ? 101  TRP A O   1 
ATOM   612  C CB  . TRP A 1 142  ? 114.498 94.163  115.941 1.00 42.54  ? 101  TRP A CB  1 
ATOM   613  C CG  . TRP A 1 142  ? 115.864 93.581  115.733 1.00 42.54  ? 101  TRP A CG  1 
ATOM   614  C CD1 . TRP A 1 142  ? 116.506 93.373  114.551 1.00 42.54  ? 101  TRP A CD1 1 
ATOM   615  C CD2 . TRP A 1 142  ? 116.756 93.129  116.756 1.00 42.54  ? 101  TRP A CD2 1 
ATOM   616  N NE1 . TRP A 1 142  ? 117.741 92.821  114.772 1.00 42.54  ? 101  TRP A NE1 1 
ATOM   617  C CE2 . TRP A 1 142  ? 117.919 92.661  116.121 1.00 42.54  ? 101  TRP A CE2 1 
ATOM   618  C CE3 . TRP A 1 142  ? 116.682 93.076  118.151 1.00 42.54  ? 101  TRP A CE3 1 
ATOM   619  C CZ2 . TRP A 1 142  ? 118.998 92.145  116.829 1.00 42.54  ? 101  TRP A CZ2 1 
ATOM   620  C CZ3 . TRP A 1 142  ? 117.755 92.566  118.852 1.00 42.54  ? 101  TRP A CZ3 1 
ATOM   621  C CH2 . TRP A 1 142  ? 118.899 92.108  118.191 1.00 42.54  ? 101  TRP A CH2 1 
ATOM   622  N N   . ALA A 1 143  ? 112.783 92.437  114.116 1.00 38.62  ? 102  ALA A N   1 
ATOM   623  C CA  . ALA A 1 143  ? 112.618 91.247  113.286 1.00 38.62  ? 102  ALA A CA  1 
ATOM   624  C C   . ALA A 1 143  ? 111.974 91.591  111.949 1.00 38.62  ? 102  ALA A C   1 
ATOM   625  O O   . ALA A 1 143  ? 112.430 91.135  110.891 1.00 38.62  ? 102  ALA A O   1 
ATOM   626  C CB  . ALA A 1 143  ? 111.792 90.201  114.031 1.00 38.62  ? 102  ALA A CB  1 
ATOM   627  N N   . SER A 1 144  ? 110.920 92.407  111.972 1.00 40.59  ? 103  SER A N   1 
ATOM   628  C CA  . SER A 1 144  ? 110.182 92.706  110.752 1.00 40.59  ? 103  SER A CA  1 
ATOM   629  C C   . SER A 1 144  ? 111.025 93.513  109.776 1.00 40.59  ? 103  SER A C   1 
ATOM   630  O O   . SER A 1 144  ? 111.028 93.237  108.574 1.00 40.59  ? 103  SER A O   1 
ATOM   631  C CB  . SER A 1 144  ? 108.895 93.449  111.094 1.00 40.59  ? 103  SER A CB  1 
ATOM   632  O OG  . SER A 1 144  ? 109.178 94.652  111.780 1.00 40.59  ? 103  SER A OG  1 
ATOM   633  N N   . SER A 1 145  ? 111.741 94.525  110.270 1.00 40.05  ? 104  SER A N   1 
ATOM   634  C CA  . SER A 1 145  ? 112.578 95.332  109.391 1.00 40.05  ? 104  SER A CA  1 
ATOM   635  C C   . SER A 1 145  ? 113.715 94.505  108.812 1.00 40.05  ? 104  SER A C   1 
ATOM   636  O O   . SER A 1 145  ? 114.035 94.620  107.622 1.00 40.05  ? 104  SER A O   1 
ATOM   637  C CB  . SER A 1 145  ? 113.119 96.540  110.150 1.00 40.05  ? 104  SER A CB  1 
ATOM   638  O OG  . SER A 1 145  ? 113.871 96.133  111.276 1.00 40.05  ? 104  SER A OG  1 
ATOM   639  N N   . TRP A 1 146  ? 114.338 93.660  109.638 1.00 41.75  ? 105  TRP A N   1 
ATOM   640  C CA  . TRP A 1 146  ? 115.383 92.777  109.136 1.00 41.75  ? 105  TRP A CA  1 
ATOM   641  C C   . TRP A 1 146  ? 114.861 91.907  108.003 1.00 41.75  ? 105  TRP A C   1 
ATOM   642  O O   . TRP A 1 146  ? 115.440 91.871  106.906 1.00 41.75  ? 105  TRP A O   1 
ATOM   643  C CB  . TRP A 1 146  ? 115.909 91.918  110.286 1.00 41.75  ? 105  TRP A CB  1 
ATOM   644  C CG  . TRP A 1 146  ? 117.114 91.090  109.979 1.00 41.75  ? 105  TRP A CG  1 
ATOM   645  C CD1 . TRP A 1 146  ? 117.703 90.905  108.767 1.00 41.75  ? 105  TRP A CD1 1 
ATOM   646  C CD2 . TRP A 1 146  ? 117.883 90.332  110.918 1.00 41.75  ? 105  TRP A CD2 1 
ATOM   647  N NE1 . TRP A 1 146  ? 118.790 90.076  108.889 1.00 41.75  ? 105  TRP A NE1 1 
ATOM   648  C CE2 . TRP A 1 146  ? 118.923 89.712  110.202 1.00 41.75  ? 105  TRP A CE2 1 
ATOM   649  C CE3 . TRP A 1 146  ? 117.793 90.119  112.296 1.00 41.75  ? 105  TRP A CE3 1 
ATOM   650  C CZ2 . TRP A 1 146  ? 119.866 88.893  110.815 1.00 41.75  ? 105  TRP A CZ2 1 
ATOM   651  C CZ3 . TRP A 1 146  ? 118.729 89.306  112.904 1.00 41.75  ? 105  TRP A CZ3 1 
ATOM   652  C CH2 . TRP A 1 146  ? 119.752 88.703  112.164 1.00 41.75  ? 105  TRP A CH2 1 
ATOM   653  N N   . ALA A 1 147  ? 113.747 91.210  108.246 1.00 42.03  ? 106  ALA A N   1 
ATOM   654  C CA  . ALA A 1 147  ? 113.193 90.326  107.230 1.00 42.03  ? 106  ALA A CA  1 
ATOM   655  C C   . ALA A 1 147  ? 112.841 91.099  105.969 1.00 42.03  ? 106  ALA A C   1 
ATOM   656  O O   . ALA A 1 147  ? 113.210 90.699  104.861 1.00 42.03  ? 106  ALA A O   1 
ATOM   657  C CB  . ALA A 1 147  ? 111.966 89.601  107.778 1.00 42.03  ? 106  ALA A CB  1 
ATOM   658  N N   . GLU A 1 148  ? 112.156 92.233  106.122 1.00 41.58  ? 107  GLU A N   1 
ATOM   659  C CA  . GLU A 1 148  ? 111.726 93.005  104.964 1.00 41.58  ? 107  GLU A CA  1 
ATOM   660  C C   . GLU A 1 148  ? 112.912 93.427  104.114 1.00 41.58  ? 107  GLU A C   1 
ATOM   661  O O   . GLU A 1 148  ? 112.976 93.111  102.918 1.00 41.58  ? 107  GLU A O   1 
ATOM   662  C CB  . GLU A 1 148  ? 110.942 94.230  105.425 1.00 41.58  ? 107  GLU A CB  1 
ATOM   663  C CG  . GLU A 1 148  ? 110.714 95.256  104.340 1.00 41.58  ? 107  GLU A CG  1 
ATOM   664  C CD  . GLU A 1 148  ? 110.283 96.594  104.895 1.00 41.58  ? 107  GLU A CD  1 
ATOM   665  O OE1 . GLU A 1 148  ? 110.194 96.723  106.131 1.00 41.58  ? 107  GLU A OE1 1 
ATOM   666  O OE2 . GLU A 1 148  ? 110.034 97.518  104.095 1.00 41.58  ? 107  GLU A OE2 1 
ATOM   667  N N   . ILE A 1 149  ? 113.885 94.104  104.723 1.00 44.23  ? 108  ILE A N   1 
ATOM   668  C CA  . ILE A 1 149  ? 115.008 94.634  103.957 1.00 44.23  ? 108  ILE A CA  1 
ATOM   669  C C   . ILE A 1 149  ? 115.767 93.504  103.277 1.00 44.23  ? 108  ILE A C   1 
ATOM   670  O O   . ILE A 1 149  ? 115.963 93.513  102.054 1.00 44.23  ? 108  ILE A O   1 
ATOM   671  C CB  . ILE A 1 149  ? 115.932 95.465  104.862 1.00 44.23  ? 108  ILE A CB  1 
ATOM   672  C CG1 . ILE A 1 149  ? 115.192 96.689  105.399 1.00 44.23  ? 108  ILE A CG1 1 
ATOM   673  C CG2 . ILE A 1 149  ? 117.179 95.875  104.110 1.00 44.23  ? 108  ILE A CG2 1 
ATOM   674  C CD1 . ILE A 1 149  ? 115.945 97.432  106.472 1.00 44.23  ? 108  ILE A CD1 1 
ATOM   675  N N   . SER A 1 150  ? 116.170 92.494  104.053 1.00 46.09  ? 109  SER A N   1 
ATOM   676  C CA  . SER A 1 150  ? 117.013 91.443  103.500 1.00 46.09  ? 109  SER A CA  1 
ATOM   677  C C   . SER A 1 150  ? 116.294 90.680  102.396 1.00 46.09  ? 109  SER A C   1 
ATOM   678  O O   . SER A 1 150  ? 116.825 90.514  101.289 1.00 46.09  ? 109  SER A O   1 
ATOM   679  C CB  . SER A 1 150  ? 117.456 90.496  104.611 1.00 46.09  ? 109  SER A CB  1 
ATOM   680  O OG  . SER A 1 150  ? 118.275 91.170  105.547 1.00 46.09  ? 109  SER A OG  1 
ATOM   681  N N   . CYS A 1 151  ? 115.078 90.206  102.679 1.00 46.88  ? 110  CYS A N   1 
ATOM   682  C CA  . CYS A 1 151  ? 114.368 89.377  101.717 1.00 46.88  ? 110  CYS A CA  1 
ATOM   683  C C   . CYS A 1 151  ? 114.060 90.151  100.445 1.00 46.88  ? 110  CYS A C   1 
ATOM   684  O O   . CYS A 1 151  ? 114.260 89.643  99.338  1.00 46.88  ? 110  CYS A O   1 
ATOM   685  C CB  . CYS A 1 151  ? 113.089 88.827  102.345 1.00 46.88  ? 110  CYS A CB  1 
ATOM   686  S SG  . CYS A 1 151  ? 113.384 87.681  103.709 1.00 46.88  ? 110  CYS A SG  1 
ATOM   687  N N   . TRP A 1 152  ? 113.583 91.391  100.573 1.00 48.87  ? 111  TRP A N   1 
ATOM   688  C CA  . TRP A 1 152  ? 113.220 92.140  99.378  1.00 48.87  ? 111  TRP A CA  1 
ATOM   689  C C   . TRP A 1 152  ? 114.445 92.440  98.522  1.00 48.87  ? 111  TRP A C   1 
ATOM   690  O O   . TRP A 1 152  ? 114.429 92.232  97.301  1.00 48.87  ? 111  TRP A O   1 
ATOM   691  C CB  . TRP A 1 152  ? 112.488 93.419  99.773  1.00 48.87  ? 111  TRP A CB  1 
ATOM   692  C CG  . TRP A 1 152  ? 111.030 93.193  99.986  1.00 48.87  ? 111  TRP A CG  1 
ATOM   693  C CD1 . TRP A 1 152  ? 110.332 93.390  101.136 1.00 48.87  ? 111  TRP A CD1 1 
ATOM   694  C CD2 . TRP A 1 152  ? 110.090 92.700  99.025  1.00 48.87  ? 111  TRP A CD2 1 
ATOM   695  N NE1 . TRP A 1 152  ? 109.014 93.063  100.951 1.00 48.87  ? 111  TRP A NE1 1 
ATOM   696  C CE2 . TRP A 1 152  ? 108.840 92.635  99.664  1.00 48.87  ? 111  TRP A CE2 1 
ATOM   697  C CE3 . TRP A 1 152  ? 110.184 92.316  97.686  1.00 48.87  ? 111  TRP A CE3 1 
ATOM   698  C CZ2 . TRP A 1 152  ? 107.694 92.202  99.011  1.00 48.87  ? 111  TRP A CZ2 1 
ATOM   699  C CZ3 . TRP A 1 152  ? 109.046 91.885  97.043  1.00 48.87  ? 111  TRP A CZ3 1 
ATOM   700  C CH2 . TRP A 1 152  ? 107.817 91.831  97.704  1.00 48.87  ? 111  TRP A CH2 1 
ATOM   701  N N   . MET A 1 153  ? 115.534 92.896  99.152  1.00 49.49  ? 112  MET A N   1 
ATOM   702  C CA  . MET A 1 153  ? 116.744 93.187  98.391  1.00 49.49  ? 112  MET A CA  1 
ATOM   703  C C   . MET A 1 153  ? 117.253 91.948  97.668  1.00 49.49  ? 112  MET A C   1 
ATOM   704  O O   . MET A 1 153  ? 117.521 91.984  96.459  1.00 49.49  ? 112  MET A O   1 
ATOM   705  C CB  . MET A 1 153  ? 117.823 93.746  99.318  1.00 49.49  ? 112  MET A CB  1 
ATOM   706  C CG  . MET A 1 153  ? 118.899 94.539  98.607  1.00 49.49  ? 112  MET A CG  1 
ATOM   707  S SD  . MET A 1 153  ? 120.085 95.298  99.732  1.00 49.49  ? 112  MET A SD  1 
ATOM   708  C CE  . MET A 1 153  ? 118.992 96.163  100.850 1.00 49.49  ? 112  MET A CE  1 
ATOM   709  N N   . TRP A 1 154  ? 117.375 90.828  98.387  1.00 50.22  ? 113  TRP A N   1 
ATOM   710  C CA  . TRP A 1 154  ? 117.970 89.644  97.777  1.00 50.22  ? 113  TRP A CA  1 
ATOM   711  C C   . TRP A 1 154  ? 117.067 89.051  96.703  1.00 50.22  ? 113  TRP A C   1 
ATOM   712  O O   . TRP A 1 154  ? 117.555 88.604  95.659  1.00 50.22  ? 113  TRP A O   1 
ATOM   713  C CB  . TRP A 1 154  ? 118.297 88.607  98.846  1.00 50.22  ? 113  TRP A CB  1 
ATOM   714  C CG  . TRP A 1 154  ? 119.212 87.538  98.350  1.00 50.22  ? 113  TRP A CG  1 
ATOM   715  C CD1 . TRP A 1 154  ? 120.261 87.694  97.496  1.00 50.22  ? 113  TRP A CD1 1 
ATOM   716  C CD2 . TRP A 1 154  ? 119.178 86.150  98.694  1.00 50.22  ? 113  TRP A CD2 1 
ATOM   717  N NE1 . TRP A 1 154  ? 120.875 86.488  97.275  1.00 50.22  ? 113  TRP A NE1 1 
ATOM   718  C CE2 . TRP A 1 154  ? 120.229 85.523  98.001  1.00 50.22  ? 113  TRP A CE2 1 
ATOM   719  C CE3 . TRP A 1 154  ? 118.359 85.375  99.520  1.00 50.22  ? 113  TRP A CE3 1 
ATOM   720  C CZ2 . TRP A 1 154  ? 120.483 84.160  98.105  1.00 50.22  ? 113  TRP A CZ2 1 
ATOM   721  C CZ3 . TRP A 1 154  ? 118.611 84.023  99.621  1.00 50.22  ? 113  TRP A CZ3 1 
ATOM   722  C CH2 . TRP A 1 154  ? 119.664 83.428  98.919  1.00 50.22  ? 113  TRP A CH2 1 
ATOM   723  N N   . SER A 1 155  ? 115.752 89.035  96.931  1.00 51.52  ? 114  SER A N   1 
ATOM   724  C CA  . SER A 1 155  ? 114.839 88.505  95.926  1.00 51.52  ? 114  SER A CA  1 
ATOM   725  C C   . SER A 1 155  ? 114.885 89.336  94.653  1.00 51.52  ? 114  SER A C   1 
ATOM   726  O O   . SER A 1 155  ? 114.951 88.791  93.542  1.00 51.52  ? 114  SER A O   1 
ATOM   727  C CB  . SER A 1 155  ? 113.420 88.459  96.484  1.00 51.52  ? 114  SER A CB  1 
ATOM   728  O OG  . SER A 1 155  ? 112.497 88.082  95.481  1.00 51.52  ? 114  SER A OG  1 
ATOM   729  N N   . GLY A 1 156  ? 114.852 90.664  94.792  1.00 57.67  ? 115  GLY A N   1 
ATOM   730  C CA  . GLY A 1 156  ? 114.948 91.507  93.616  1.00 57.67  ? 115  GLY A CA  1 
ATOM   731  C C   . GLY A 1 156  ? 116.244 91.289  92.864  1.00 57.67  ? 115  GLY A C   1 
ATOM   732  O O   . GLY A 1 156  ? 116.252 91.190  91.634  1.00 57.67  ? 115  GLY A O   1 
ATOM   733  N N   . GLU A 1 157  ? 117.356 91.185  93.595  1.00 56.52  ? 116  GLU A N   1 
ATOM   734  C CA  . GLU A 1 157  ? 118.644 90.985  92.943  1.00 56.52  ? 116  GLU A CA  1 
ATOM   735  C C   . GLU A 1 157  ? 118.682 89.661  92.191  1.00 56.52  ? 116  GLU A C   1 
ATOM   736  O O   . GLU A 1 157  ? 119.174 89.593  91.061  1.00 56.52  ? 116  GLU A O   1 
ATOM   737  C CB  . GLU A 1 157  ? 119.767 91.056  93.976  1.00 56.52  ? 116  GLU A CB  1 
ATOM   738  C CG  . GLU A 1 157  ? 121.125 90.660  93.442  1.00 56.52  ? 116  GLU A CG  1 
ATOM   739  C CD  . GLU A 1 157  ? 121.749 91.738  92.577  1.00 56.52  ? 116  GLU A CD  1 
ATOM   740  O OE1 . GLU A 1 157  ? 121.156 92.830  92.459  1.00 56.52  ? 116  GLU A OE1 1 
ATOM   741  O OE2 . GLU A 1 157  ? 122.836 91.495  92.014  1.00 56.52  ? 116  GLU A OE2 1 
ATOM   742  N N   . ARG A 1 158  ? 118.157 88.595  92.799  1.00 54.06  ? 117  ARG A N   1 
ATOM   743  C CA  . ARG A 1 158  ? 118.172 87.289  92.145  1.00 54.06  ? 117  ARG A CA  1 
ATOM   744  C C   . ARG A 1 158  ? 117.337 87.292  90.871  1.00 54.06  ? 117  ARG A C   1 
ATOM   745  O O   . ARG A 1 158  ? 117.789 86.823  89.814  1.00 54.06  ? 117  ARG A O   1 
ATOM   746  C CB  . ARG A 1 158  ? 117.666 86.215  93.105  1.00 54.06  ? 117  ARG A CB  1 
ATOM   747  C CG  . ARG A 1 158  ? 118.661 85.805  94.166  1.00 54.06  ? 117  ARG A CG  1 
ATOM   748  C CD  . ARG A 1 158  ? 118.061 84.749  95.067  1.00 54.06  ? 117  ARG A CD  1 
ATOM   749  N NE  . ARG A 1 158  ? 117.116 83.910  94.343  1.00 54.06  ? 117  ARG A NE  1 
ATOM   750  C CZ  . ARG A 1 158  ? 117.294 82.620  94.100  1.00 54.06  ? 117  ARG A CZ  1 
ATOM   751  N NH1 . ARG A 1 158  ? 118.385 81.988  94.496  1.00 54.06  ? 117  ARG A NH1 1 
ATOM   752  N NH2 . ARG A 1 158  ? 116.358 81.949  93.436  1.00 54.06  ? 117  ARG A NH2 1 
ATOM   753  N N   . GLN A 1 159  ? 116.106 87.804  90.952  1.00 53.49  ? 118  GLN A N   1 
ATOM   754  C CA  . GLN A 1 159  ? 115.256 87.836  89.765  1.00 53.49  ? 118  GLN A CA  1 
ATOM   755  C C   . GLN A 1 159  ? 115.893 88.667  88.662  1.00 53.49  ? 118  GLN A C   1 
ATOM   756  O O   . GLN A 1 159  ? 115.896 88.272  87.489  1.00 53.49  ? 118  GLN A O   1 
ATOM   757  C CB  . GLN A 1 159  ? 113.875 88.388  90.111  1.00 53.49  ? 118  GLN A CB  1 
ATOM   758  C CG  . GLN A 1 159  ? 113.196 87.716  91.276  1.00 53.49  ? 118  GLN A CG  1 
ATOM   759  C CD  . GLN A 1 159  ? 111.706 87.967  91.289  1.00 53.49  ? 118  GLN A CD  1 
ATOM   760  O OE1 . GLN A 1 159  ? 111.058 87.971  90.244  1.00 53.49  ? 118  GLN A OE1 1 
ATOM   761  N NE2 . GLN A 1 159  ? 111.155 88.183  92.473  1.00 53.49  ? 118  GLN A NE2 1 
ATOM   762  N N   . THR A 1 160  ? 116.454 89.821  89.024  1.00 53.69  ? 119  THR A N   1 
ATOM   763  C CA  . THR A 1 160  ? 117.024 90.701  88.015  1.00 53.69  ? 119  THR A CA  1 
ATOM   764  C C   . THR A 1 160  ? 118.275 90.093  87.393  1.00 53.69  ? 119  THR A C   1 
ATOM   765  O O   . THR A 1 160  ? 118.525 90.272  86.200  1.00 53.69  ? 119  THR A O   1 
ATOM   766  C CB  . THR A 1 160  ? 117.324 92.062  88.628  1.00 53.69  ? 119  THR A CB  1 
ATOM   767  O OG1 . THR A 1 160  ? 116.109 92.611  89.148  1.00 53.69  ? 119  THR A OG1 1 
ATOM   768  C CG2 . THR A 1 160  ? 117.859 93.002  87.581  1.00 53.69  ? 119  THR A CG2 1 
ATOM   769  N N   . THR A 1 161  ? 119.067 89.357  88.175  1.00 54.54  ? 120  THR A N   1 
ATOM   770  C CA  . THR A 1 161  ? 120.237 88.695  87.609  1.00 54.54  ? 120  THR A CA  1 
ATOM   771  C C   . THR A 1 161  ? 119.835 87.598  86.631  1.00 54.54  ? 120  THR A C   1 
ATOM   772  O O   . THR A 1 161  ? 120.416 87.474  85.545  1.00 54.54  ? 120  THR A O   1 
ATOM   773  C CB  . THR A 1 161  ? 121.114 88.126  88.722  1.00 54.54  ? 120  THR A CB  1 
ATOM   774  O OG1 . THR A 1 161  ? 121.648 89.203  89.501  1.00 54.54  ? 120  THR A OG1 1 
ATOM   775  C CG2 . THR A 1 161  ? 122.254 87.318  88.140  1.00 54.54  ? 120  THR A CG2 1 
ATOM   776  N N   . LYS A 1 162  ? 118.838 86.786  86.997  1.00 54.15  ? 121  LYS A N   1 
ATOM   777  C CA  . LYS A 1 162  ? 118.376 85.756  86.071  1.00 54.15  ? 121  LYS A CA  1 
ATOM   778  C C   . LYS A 1 162  ? 117.860 86.377  84.781  1.00 54.15  ? 121  LYS A C   1 
ATOM   779  O O   . LYS A 1 162  ? 118.159 85.896  83.679  1.00 54.15  ? 121  LYS A O   1 
ATOM   780  C CB  . LYS A 1 162  ? 117.284 84.909  86.718  1.00 54.15  ? 121  LYS A CB  1 
ATOM   781  C CG  . LYS A 1 162  ? 117.793 83.732  87.513  1.00 54.15  ? 121  LYS A CG  1 
ATOM   782  C CD  . LYS A 1 162  ? 116.664 82.777  87.844  1.00 54.15  ? 121  LYS A CD  1 
ATOM   783  C CE  . LYS A 1 162  ? 116.985 81.968  89.083  1.00 54.15  ? 121  LYS A CE  1 
ATOM   784  N NZ  . LYS A 1 162  ? 117.138 82.847  90.273  1.00 54.15  ? 121  LYS A NZ  1 
ATOM   785  N N   . MET A 1 163  ? 117.088 87.456  84.903  1.00 57.29  ? 122  MET A N   1 
ATOM   786  C CA  . MET A 1 163  ? 116.560 88.131  83.725  1.00 57.29  ? 122  MET A CA  1 
ATOM   787  C C   . MET A 1 163  ? 117.667 88.774  82.898  1.00 57.29  ? 122  MET A C   1 
ATOM   788  O O   . MET A 1 163  ? 117.592 88.792  81.667  1.00 57.29  ? 122  MET A O   1 
ATOM   789  C CB  . MET A 1 163  ? 115.506 89.142  84.160  1.00 57.29  ? 122  MET A CB  1 
ATOM   790  C CG  . MET A 1 163  ? 115.017 90.074  83.096  1.00 57.29  ? 122  MET A CG  1 
ATOM   791  S SD  . MET A 1 163  ? 114.416 91.536  83.940  1.00 57.29  ? 122  MET A SD  1 
ATOM   792  C CE  . MET A 1 163  ? 115.927 92.455  84.053  1.00 57.29  ? 122  MET A CE  1 
ATOM   793  N N   . ARG A 1 164  ? 118.712 89.286  83.549  1.00 59.72  ? 123  ARG A N   1 
ATOM   794  C CA  . ARG A 1 164  ? 119.857 89.831  82.825  1.00 59.72  ? 123  ARG A CA  1 
ATOM   795  C C   . ARG A 1 164  ? 120.538 88.750  81.998  1.00 59.72  ? 123  ARG A C   1 
ATOM   796  O O   . ARG A 1 164  ? 120.866 88.956  80.822  1.00 59.72  ? 123  ARG A O   1 
ATOM   797  C CB  . ARG A 1 164  ? 120.857 90.419  83.814  1.00 59.72  ? 123  ARG A CB  1 
ATOM   798  C CG  . ARG A 1 164  ? 120.873 91.918  83.943  1.00 59.72  ? 123  ARG A CG  1 
ATOM   799  C CD  . ARG A 1 164  ? 122.111 92.315  84.719  1.00 59.72  ? 123  ARG A CD  1 
ATOM   800  N NE  . ARG A 1 164  ? 121.964 92.070  86.148  1.00 59.72  ? 123  ARG A NE  1 
ATOM   801  C CZ  . ARG A 1 164  ? 121.307 92.859  86.983  1.00 59.72  ? 123  ARG A CZ  1 
ATOM   802  N NH1 . ARG A 1 164  ? 120.745 93.978  86.573  1.00 59.72  ? 123  ARG A NH1 1 
ATOM   803  N NH2 . ARG A 1 164  ? 121.217 92.518  88.266  1.00 59.72  ? 123  ARG A NH2 1 
ATOM   804  N N   . ILE A 1 165  ? 120.777 87.591  82.615  1.00 60.33  ? 124  ILE A N   1 
ATOM   805  C CA  . ILE A 1 165  ? 121.443 86.494  81.919  1.00 60.33  ? 124  ILE A CA  1 
ATOM   806  C C   . ILE A 1 165  ? 120.613 86.054  80.722  1.00 60.33  ? 124  ILE A C   1 
ATOM   807  O O   . ILE A 1 165  ? 121.133 85.870  79.614  1.00 60.33  ? 124  ILE A O   1 
ATOM   808  C CB  . ILE A 1 165  ? 121.696 85.319  82.879  1.00 60.33  ? 124  ILE A CB  1 
ATOM   809  C CG1 . ILE A 1 165  ? 122.579 85.748  84.049  1.00 60.33  ? 124  ILE A CG1 1 
ATOM   810  C CG2 . ILE A 1 165  ? 122.337 84.164  82.138  1.00 60.33  ? 124  ILE A CG2 1 
ATOM   811  C CD1 . ILE A 1 165  ? 124.001 86.018  83.674  1.00 60.33  ? 124  ILE A CD1 1 
ATOM   812  N N   . LYS A 1 166  ? 119.305 85.880  80.930  1.00 63.20  ? 125  LYS A N   1 
ATOM   813  C CA  . LYS A 1 166  ? 118.448 85.441  79.834  1.00 63.20  ? 125  LYS A CA  1 
ATOM   814  C C   . LYS A 1 166  ? 118.381 86.490  78.732  1.00 63.20  ? 125  LYS A C   1 
ATOM   815  O O   . LYS A 1 166  ? 118.351 86.149  77.544  1.00 63.20  ? 125  LYS A O   1 
ATOM   816  C CB  . LYS A 1 166  ? 117.053 85.111  80.354  1.00 63.20  ? 125  LYS A CB  1 
ATOM   817  C CG  . LYS A 1 166  ? 116.138 84.534  79.297  1.00 63.20  ? 125  LYS A CG  1 
ATOM   818  C CD  . LYS A 1 166  ? 115.270 83.426  79.858  1.00 63.20  ? 125  LYS A CD  1 
ATOM   819  C CE  . LYS A 1 166  ? 114.762 82.524  78.747  1.00 63.20  ? 125  LYS A CE  1 
ATOM   820  N NZ  . LYS A 1 166  ? 115.662 81.360  78.525  1.00 63.20  ? 125  LYS A NZ  1 
ATOM   821  N N   . TYR A 1 167  ? 118.363 87.771  79.103  1.00 65.64  ? 126  TYR A N   1 
ATOM   822  C CA  . TYR A 1 167  ? 118.358 88.837  78.109  1.00 65.64  ? 126  TYR A CA  1 
ATOM   823  C C   . TYR A 1 167  ? 119.610 88.798  77.249  1.00 65.64  ? 126  TYR A C   1 
ATOM   824  O O   . TYR A 1 167  ? 119.535 88.911  76.022  1.00 65.64  ? 126  TYR A O   1 
ATOM   825  C CB  . TYR A 1 167  ? 118.237 90.191  78.801  1.00 65.64  ? 126  TYR A CB  1 
ATOM   826  C CG  . TYR A 1 167  ? 118.267 91.359  77.853  1.00 65.64  ? 126  TYR A CG  1 
ATOM   827  C CD1 . TYR A 1 167  ? 117.182 91.652  77.048  1.00 65.64  ? 126  TYR A CD1 1 
ATOM   828  C CD2 . TYR A 1 167  ? 119.392 92.159  77.751  1.00 65.64  ? 126  TYR A CD2 1 
ATOM   829  C CE1 . TYR A 1 167  ? 117.211 92.721  76.185  1.00 65.64  ? 126  TYR A CE1 1 
ATOM   830  C CE2 . TYR A 1 167  ? 119.430 93.225  76.887  1.00 65.64  ? 126  TYR A CE2 1 
ATOM   831  C CZ  . TYR A 1 167  ? 118.337 93.501  76.106  1.00 65.64  ? 126  TYR A CZ  1 
ATOM   832  O OH  . TYR A 1 167  ? 118.371 94.566  75.241  1.00 65.64  ? 126  TYR A OH  1 
ATOM   833  N N   . LEU A 1 168  ? 120.779 88.649  77.876  1.00 65.83  ? 127  LEU A N   1 
ATOM   834  C CA  . LEU A 1 168  ? 122.013 88.596  77.097  1.00 65.83  ? 127  LEU A CA  1 
ATOM   835  C C   . LEU A 1 168  ? 122.035 87.368  76.197  1.00 65.83  ? 127  LEU A C   1 
ATOM   836  O O   . LEU A 1 168  ? 122.439 87.447  75.031  1.00 65.83  ? 127  LEU A O   1 
ATOM   837  C CB  . LEU A 1 168  ? 123.235 88.604  78.012  1.00 65.83  ? 127  LEU A CB  1 
ATOM   838  C CG  . LEU A 1 168  ? 124.538 88.498  77.217  1.00 65.83  ? 127  LEU A CG  1 
ATOM   839  C CD1 . LEU A 1 168  ? 124.923 89.847  76.644  1.00 65.83  ? 127  LEU A CD1 1 
ATOM   840  C CD2 . LEU A 1 168  ? 125.664 87.931  78.053  1.00 65.83  ? 127  LEU A CD2 1 
ATOM   841  N N   . GLU A 1 169  ? 121.602 86.221  76.723  1.00 71.71  ? 128  GLU A N   1 
ATOM   842  C CA  . GLU A 1 169  ? 121.571 85.008  75.916  1.00 71.71  ? 128  GLU A CA  1 
ATOM   843  C C   . GLU A 1 169  ? 120.669 85.179  74.702  1.00 71.71  ? 128  GLU A C   1 
ATOM   844  O O   . GLU A 1 169  ? 121.024 84.780  73.589  1.00 71.71  ? 128  GLU A O   1 
ATOM   845  C CB  . GLU A 1 169  ? 121.108 83.825  76.764  1.00 71.71  ? 128  GLU A CB  1 
ATOM   846  C CG  . GLU A 1 169  ? 120.709 82.606  75.956  1.00 71.71  ? 128  GLU A CG  1 
ATOM   847  C CD  . GLU A 1 169  ? 119.960 81.582  76.783  1.00 71.71  ? 128  GLU A CD  1 
ATOM   848  O OE1 . GLU A 1 169  ? 120.532 81.083  77.774  1.00 71.71  ? 128  GLU A OE1 1 
ATOM   849  O OE2 . GLU A 1 169  ? 118.798 81.278  76.445  1.00 71.71  ? 128  GLU A OE2 1 
ATOM   850  N N   . ALA A 1 170  ? 119.494 85.778  74.899  1.00 72.66  ? 129  ALA A N   1 
ATOM   851  C CA  . ALA A 1 170  ? 118.582 85.993  73.783  1.00 72.66  ? 129  ALA A CA  1 
ATOM   852  C C   . ALA A 1 170  ? 119.148 87.001  72.793  1.00 72.66  ? 129  ALA A C   1 
ATOM   853  O O   . ALA A 1 170  ? 118.958 86.862  71.580  1.00 72.66  ? 129  ALA A O   1 
ATOM   854  C CB  . ALA A 1 170  ? 117.221 86.455  74.298  1.00 72.66  ? 129  ALA A CB  1 
ATOM   855  N N   . ALA A 1 171  ? 119.835 88.030  73.288  1.00 72.64  ? 130  ALA A N   1 
ATOM   856  C CA  . ALA A 1 171  ? 120.388 89.039  72.394  1.00 72.64  ? 130  ALA A CA  1 
ATOM   857  C C   . ALA A 1 171  ? 121.510 88.471  71.536  1.00 72.64  ? 130  ALA A C   1 
ATOM   858  O O   . ALA A 1 171  ? 121.628 88.814  70.356  1.00 72.64  ? 130  ALA A O   1 
ATOM   859  C CB  . ALA A 1 171  ? 120.883 90.239  73.197  1.00 72.64  ? 130  ALA A CB  1 
ATOM   860  N N   . LEU A 1 172  ? 122.347 87.605  72.111  1.00 74.39  ? 131  LEU A N   1 
ATOM   861  C CA  . LEU A 1 172  ? 123.513 87.119  71.378  1.00 74.39  ? 131  LEU A CA  1 
ATOM   862  C C   . LEU A 1 172  ? 123.117 86.267  70.180  1.00 74.39  ? 131  LEU A C   1 
ATOM   863  O O   . LEU A 1 172  ? 123.655 86.445  69.082  1.00 74.39  ? 131  LEU A O   1 
ATOM   864  C CB  . LEU A 1 172  ? 124.434 86.334  72.309  1.00 74.39  ? 131  LEU A CB  1 
ATOM   865  C CG  . LEU A 1 172  ? 125.367 87.185  73.166  1.00 74.39  ? 131  LEU A CG  1 
ATOM   866  C CD1 . LEU A 1 172  ? 126.478 86.334  73.739  1.00 74.39  ? 131  LEU A CD1 1 
ATOM   867  C CD2 . LEU A 1 172  ? 125.937 88.324  72.350  1.00 74.39  ? 131  LEU A CD2 1 
ATOM   868  N N   . ASN A 1 173  ? 122.179 85.341  70.359  1.00 83.61  ? 132  ASN A N   1 
ATOM   869  C CA  . ASN A 1 173  ? 121.814 84.432  69.282  1.00 83.61  ? 132  ASN A CA  1 
ATOM   870  C C   . ASN A 1 173  ? 120.761 85.011  68.347  1.00 83.61  ? 132  ASN A C   1 
ATOM   871  O O   . ASN A 1 173  ? 120.083 84.252  67.649  1.00 83.61  ? 132  ASN A O   1 
ATOM   872  C CB  . ASN A 1 173  ? 121.350 83.084  69.849  1.00 83.61  ? 132  ASN A CB  1 
ATOM   873  C CG  . ASN A 1 173  ? 120.091 83.189  70.684  1.00 83.61  ? 132  ASN A CG  1 
ATOM   874  O OD1 . ASN A 1 173  ? 119.461 84.241  70.764  1.00 83.61  ? 132  ASN A OD1 1 
ATOM   875  N ND2 . ASN A 1 173  ? 119.714 82.083  71.314  1.00 83.61  ? 132  ASN A ND2 1 
ATOM   876  N N   . GLN A 1 174  ? 120.605 86.331  68.325  1.00 89.56  ? 133  GLN A N   1 
ATOM   877  C CA  . GLN A 1 174  ? 119.752 86.979  67.345  1.00 89.56  ? 133  GLN A CA  1 
ATOM   878  C C   . GLN A 1 174  ? 120.527 87.211  66.052  1.00 89.56  ? 133  GLN A C   1 
ATOM   879  O O   . GLN A 1 174  ? 121.760 87.229  66.031  1.00 89.56  ? 133  GLN A O   1 
ATOM   880  C CB  . GLN A 1 174  ? 119.226 88.307  67.888  1.00 89.56  ? 133  GLN A CB  1 
ATOM   881  C CG  . GLN A 1 174  ? 118.045 88.173  68.830  1.00 89.56  ? 133  GLN A CG  1 
ATOM   882  C CD  . GLN A 1 174  ? 116.776 87.745  68.131  1.00 89.56  ? 133  GLN A CD  1 
ATOM   883  O OE1 . GLN A 1 174  ? 116.684 87.785  66.905  1.00 89.56  ? 133  GLN A OE1 1 
ATOM   884  N NE2 . GLN A 1 174  ? 115.789 87.326  68.909  1.00 89.56  ? 133  GLN A NE2 1 
ATOM   885  N N   . ASP A 1 175  ? 119.790 87.389  64.962  1.00 104.78 ? 134  ASP A N   1 
ATOM   886  C CA  . ASP A 1 175  ? 120.421 87.644  63.676  1.00 104.78 ? 134  ASP A CA  1 
ATOM   887  C C   . ASP A 1 175  ? 121.002 89.052  63.632  1.00 104.78 ? 134  ASP A C   1 
ATOM   888  O O   . ASP A 1 175  ? 120.581 89.946  64.368  1.00 104.78 ? 134  ASP A O   1 
ATOM   889  C CB  . ASP A 1 175  ? 119.416 87.457  62.542  1.00 104.78 ? 134  ASP A CB  1 
ATOM   890  C CG  . ASP A 1 175  ? 118.858 86.054  62.490  1.00 104.78 ? 134  ASP A CG  1 
ATOM   891  O OD1 . ASP A 1 175  ? 119.347 85.195  63.252  1.00 104.78 ? 134  ASP A OD1 1 
ATOM   892  O OD2 . ASP A 1 175  ? 117.931 85.808  61.690  1.00 104.78 ? 134  ASP A OD2 1 
ATOM   893  N N   . ILE A 1 176  ? 121.993 89.242  62.761  1.00 104.55 ? 135  ILE A N   1 
ATOM   894  C CA  . ILE A 1 176  ? 122.616 90.556  62.624  1.00 104.55 ? 135  ILE A CA  1 
ATOM   895  C C   . ILE A 1 176  ? 121.626 91.552  62.034  1.00 104.55 ? 135  ILE A C   1 
ATOM   896  O O   . ILE A 1 176  ? 121.618 92.737  62.399  1.00 104.55 ? 135  ILE A O   1 
ATOM   897  C CB  . ILE A 1 176  ? 123.899 90.451  61.781  1.00 104.55 ? 135  ILE A CB  1 
ATOM   898  C CG1 . ILE A 1 176  ? 124.923 89.554  62.476  1.00 104.55 ? 135  ILE A CG1 1 
ATOM   899  C CG2 . ILE A 1 176  ? 124.498 91.824  61.545  1.00 104.55 ? 135  ILE A CG2 1 
ATOM   900  C CD1 . ILE A 1 176  ? 124.879 88.108  62.033  1.00 104.55 ? 135  ILE A CD1 1 
ATOM   901  N N   . GLN A 1 177  ? 120.774 91.090  61.117  1.00 107.74 ? 136  GLN A N   1 
ATOM   902  C CA  . GLN A 1 177  ? 119.749 91.959  60.551  1.00 107.74 ? 136  GLN A CA  1 
ATOM   903  C C   . GLN A 1 177  ? 118.780 92.453  61.617  1.00 107.74 ? 136  GLN A C   1 
ATOM   904  O O   . GLN A 1 177  ? 118.139 93.493  61.437  1.00 107.74 ? 136  GLN A O   1 
ATOM   905  C CB  . GLN A 1 177  ? 119.002 91.226  59.438  1.00 107.74 ? 136  GLN A CB  1 
ATOM   906  C CG  . GLN A 1 177  ? 117.855 90.360  59.918  1.00 107.74 ? 136  GLN A CG  1 
ATOM   907  C CD  . GLN A 1 177  ? 117.212 89.576  58.795  1.00 107.74 ? 136  GLN A CD  1 
ATOM   908  O OE1 . GLN A 1 177  ? 117.883 88.839  58.073  1.00 107.74 ? 136  GLN A OE1 1 
ATOM   909  N NE2 . GLN A 1 177  ? 115.903 89.731  58.640  1.00 107.74 ? 136  GLN A NE2 1 
ATOM   910  N N   . PHE A 1 178  ? 118.655 91.723  62.728  1.00 99.42  ? 137  PHE A N   1 
ATOM   911  C CA  . PHE A 1 178  ? 117.851 92.209  63.844  1.00 99.42  ? 137  PHE A CA  1 
ATOM   912  C C   . PHE A 1 178  ? 118.437 93.494  64.413  1.00 99.42  ? 137  PHE A C   1 
ATOM   913  O O   . PHE A 1 178  ? 117.715 94.467  64.653  1.00 99.42  ? 137  PHE A O   1 
ATOM   914  C CB  . PHE A 1 178  ? 117.753 91.135  64.927  1.00 99.42  ? 137  PHE A CB  1 
ATOM   915  C CG  . PHE A 1 178  ? 117.028 91.581  66.162  1.00 99.42  ? 137  PHE A CG  1 
ATOM   916  C CD1 . PHE A 1 178  ? 115.648 91.541  66.223  1.00 99.42  ? 137  PHE A CD1 1 
ATOM   917  C CD2 . PHE A 1 178  ? 117.729 92.038  67.265  1.00 99.42  ? 137  PHE A CD2 1 
ATOM   918  C CE1 . PHE A 1 178  ? 114.980 91.950  67.358  1.00 99.42  ? 137  PHE A CE1 1 
ATOM   919  C CE2 . PHE A 1 178  ? 117.067 92.450  68.400  1.00 99.42  ? 137  PHE A CE2 1 
ATOM   920  C CZ  . PHE A 1 178  ? 115.692 92.406  68.447  1.00 99.42  ? 137  PHE A CZ  1 
ATOM   921  N N   . PHE A 1 179  ? 119.752 93.515  64.633  1.00 100.04 ? 138  PHE A N   1 
ATOM   922  C CA  . PHE A 1 179  ? 120.387 94.723  65.144  1.00 100.04 ? 138  PHE A CA  1 
ATOM   923  C C   . PHE A 1 179  ? 120.440 95.812  64.088  1.00 100.04 ? 138  PHE A C   1 
ATOM   924  O O   . PHE A 1 179  ? 120.432 97.002  64.423  1.00 100.04 ? 138  PHE A O   1 
ATOM   925  C CB  . PHE A 1 179  ? 121.794 94.409  65.647  1.00 100.04 ? 138  PHE A CB  1 
ATOM   926  C CG  . PHE A 1 179  ? 121.842 93.291  66.640  1.00 100.04 ? 138  PHE A CG  1 
ATOM   927  C CD1 . PHE A 1 179  ? 121.637 93.535  67.984  1.00 100.04 ? 138  PHE A CD1 1 
ATOM   928  C CD2 . PHE A 1 179  ? 122.078 91.993  66.228  1.00 100.04 ? 138  PHE A CD2 1 
ATOM   929  C CE1 . PHE A 1 179  ? 121.673 92.508  68.898  1.00 100.04 ? 138  PHE A CE1 1 
ATOM   930  C CE2 . PHE A 1 179  ? 122.116 90.963  67.138  1.00 100.04 ? 138  PHE A CE2 1 
ATOM   931  C CZ  . PHE A 1 179  ? 121.913 91.221  68.474  1.00 100.04 ? 138  PHE A CZ  1 
ATOM   932  N N   . ASP A 1 180  ? 120.503 95.429  62.812  1.00 113.57 ? 139  ASP A N   1 
ATOM   933  C CA  . ASP A 1 180  ? 120.552 96.427  61.750  1.00 113.57 ? 139  ASP A CA  1 
ATOM   934  C C   . ASP A 1 180  ? 119.239 97.196  61.647  1.00 113.57 ? 139  ASP A C   1 
ATOM   935  O O   . ASP A 1 180  ? 119.242 98.413  61.423  1.00 113.57 ? 139  ASP A O   1 
ATOM   936  C CB  . ASP A 1 180  ? 120.892 95.761  60.419  1.00 113.57 ? 139  ASP A CB  1 
ATOM   937  C CG  . ASP A 1 180  ? 121.432 96.742  59.402  1.00 113.57 ? 139  ASP A CG  1 
ATOM   938  O OD1 . ASP A 1 180  ? 121.680 97.906  59.777  1.00 113.57 ? 139  ASP A OD1 1 
ATOM   939  O OD2 . ASP A 1 180  ? 121.608 96.351  58.229  1.00 113.57 ? 139  ASP A OD2 1 
ATOM   940  N N   . THR A 1 181  ? 118.107 96.509  61.805  1.00 111.62 ? 140  THR A N   1 
ATOM   941  C CA  . THR A 1 181  ? 116.801 97.114  61.562  1.00 111.62 ? 140  THR A CA  1 
ATOM   942  C C   . THR A 1 181  ? 115.964 97.241  62.828  1.00 111.62 ? 140  THR A C   1 
ATOM   943  O O   . THR A 1 181  ? 115.519 98.345  63.155  1.00 111.62 ? 140  THR A O   1 
ATOM   944  C CB  . THR A 1 181  ? 116.037 96.299  60.512  1.00 111.62 ? 140  THR A CB  1 
ATOM   945  O OG1 . THR A 1 181  ? 115.826 94.969  61.001  1.00 111.62 ? 140  THR A OG1 1 
ATOM   946  C CG2 . THR A 1 181  ? 116.826 96.232  59.221  1.00 111.62 ? 140  THR A CG2 1 
ATOM   947  N N   . GLU A 1 182  ? 115.733 96.141  63.550  1.00 107.71 ? 141  GLU A N   1 
ATOM   948  C CA  . GLU A 1 182  ? 114.759 96.146  64.637  1.00 107.71 ? 141  GLU A CA  1 
ATOM   949  C C   . GLU A 1 182  ? 115.200 97.049  65.782  1.00 107.71 ? 141  GLU A C   1 
ATOM   950  O O   . GLU A 1 182  ? 114.548 98.052  66.090  1.00 107.71 ? 141  GLU A O   1 
ATOM   951  C CB  . GLU A 1 182  ? 114.537 94.718  65.139  1.00 107.71 ? 141  GLU A CB  1 
ATOM   952  C CG  . GLU A 1 182  ? 113.905 93.787  64.121  1.00 107.71 ? 141  GLU A CG  1 
ATOM   953  C CD  . GLU A 1 182  ? 112.443 94.084  63.887  1.00 107.71 ? 141  GLU A CD  1 
ATOM   954  O OE1 . GLU A 1 182  ? 111.771 94.538  64.836  1.00 107.71 ? 141  GLU A OE1 1 
ATOM   955  O OE2 . GLU A 1 182  ? 111.965 93.862  62.756  1.00 107.71 ? 141  GLU A OE2 1 
ATOM   956  N N   . VAL A 1 183  ? 116.309 96.704  66.428  1.00 101.03 ? 142  VAL A N   1 
ATOM   957  C CA  . VAL A 1 183  ? 116.768 97.419  67.614  1.00 101.03 ? 142  VAL A CA  1 
ATOM   958  C C   . VAL A 1 183  ? 118.250 97.729  67.454  1.00 101.03 ? 142  VAL A C   1 
ATOM   959  O O   . VAL A 1 183  ? 119.051 96.843  67.147  1.00 101.03 ? 142  VAL A O   1 
ATOM   960  C CB  . VAL A 1 183  ? 116.506 96.604  68.898  1.00 101.03 ? 142  VAL A CB  1 
ATOM   961  C CG1 . VAL A 1 183  ? 117.084 97.314  70.106  1.00 101.03 ? 142  VAL A CG1 1 
ATOM   962  C CG2 . VAL A 1 183  ? 115.019 96.368  69.086  1.00 101.03 ? 142  VAL A CG2 1 
ATOM   963  N N   . ARG A 1 184  ? 118.609 98.990  67.667  1.00 99.78  ? 143  ARG A N   1 
ATOM   964  C CA  . ARG A 1 184  ? 120.004 99.394  67.591  1.00 99.78  ? 143  ARG A CA  1 
ATOM   965  C C   . ARG A 1 184  ? 120.795 98.808  68.755  1.00 99.78  ? 143  ARG A C   1 
ATOM   966  O O   . ARG A 1 184  ? 120.249 98.523  69.824  1.00 99.78  ? 143  ARG A O   1 
ATOM   967  C CB  . ARG A 1 184  ? 120.120 100.918 67.594  1.00 99.78  ? 143  ARG A CB  1 
ATOM   968  C CG  . ARG A 1 184  ? 119.339 101.617 66.487  1.00 99.78  ? 143  ARG A CG  1 
ATOM   969  C CD  . ARG A 1 184  ? 119.434 100.868 65.165  1.00 99.78  ? 143  ARG A CD  1 
ATOM   970  N NE  . ARG A 1 184  ? 118.901 101.649 64.056  1.00 99.78  ? 143  ARG A NE  1 
ATOM   971  C CZ  . ARG A 1 184  ? 119.181 101.426 62.779  1.00 99.78  ? 143  ARG A CZ  1 
ATOM   972  N NH1 . ARG A 1 184  ? 119.995 100.452 62.410  1.00 99.78  ? 143  ARG A NH1 1 
ATOM   973  N NH2 . ARG A 1 184  ? 118.632 102.203 61.849  1.00 99.78  ? 143  ARG A NH2 1 
ATOM   974  N N   . THR A 1 185  ? 122.098 98.621  68.534  1.00 93.38  ? 144  THR A N   1 
ATOM   975  C CA  . THR A 1 185  ? 122.955 98.092  69.592  1.00 93.38  ? 144  THR A CA  1 
ATOM   976  C C   . THR A 1 185  ? 123.015 99.043  70.781  1.00 93.38  ? 144  THR A C   1 
ATOM   977  O O   . THR A 1 185  ? 123.021 98.605  71.939  1.00 93.38  ? 144  THR A O   1 
ATOM   978  C CB  . THR A 1 185  ? 124.359 97.827  69.049  1.00 93.38  ? 144  THR A CB  1 
ATOM   979  O OG1 . THR A 1 185  ? 124.941 99.057  68.607  1.00 93.38  ? 144  THR A OG1 1 
ATOM   980  C CG2 . THR A 1 185  ? 124.298 96.857  67.883  1.00 93.38  ? 144  THR A CG2 1 
ATOM   981  N N   . SER A 1 186  ? 123.069 100.350 70.512  1.00 91.23  ? 145  SER A N   1 
ATOM   982  C CA  . SER A 1 186  ? 123.015 101.328 71.592  1.00 91.23  ? 145  SER A CA  1 
ATOM   983  C C   . SER A 1 186  ? 121.718 101.194 72.378  1.00 91.23  ? 145  SER A C   1 
ATOM   984  O O   . SER A 1 186  ? 121.706 101.351 73.604  1.00 91.23  ? 145  SER A O   1 
ATOM   985  C CB  . SER A 1 186  ? 123.161 102.740 71.029  1.00 91.23  ? 145  SER A CB  1 
ATOM   986  O OG  . SER A 1 186  ? 123.047 103.711 72.054  1.00 91.23  ? 145  SER A OG  1 
ATOM   987  N N   . ASP A 1 187  ? 120.618 100.896 71.685  1.00 92.26  ? 146  ASP A N   1 
ATOM   988  C CA  . ASP A 1 187  ? 119.358 100.648 72.375  1.00 92.26  ? 146  ASP A CA  1 
ATOM   989  C C   . ASP A 1 187  ? 119.452 99.417  73.267  1.00 92.26  ? 146  ASP A C   1 
ATOM   990  O O   . ASP A 1 187  ? 118.897 99.401  74.368  1.00 92.26  ? 146  ASP A O   1 
ATOM   991  C CB  . ASP A 1 187  ? 118.224 100.496 71.363  1.00 92.26  ? 146  ASP A CB  1 
ATOM   992  C CG  . ASP A 1 187  ? 117.460 101.785 71.149  1.00 92.26  ? 146  ASP A CG  1 
ATOM   993  O OD1 . ASP A 1 187  ? 117.909 102.832 71.661  1.00 92.26  ? 146  ASP A OD1 1 
ATOM   994  O OD2 . ASP A 1 187  ? 116.412 101.754 70.470  1.00 92.26  ? 146  ASP A OD2 1 
ATOM   995  N N   . VAL A 1 188  ? 120.157 98.378  72.814  1.00 84.75  ? 147  VAL A N   1 
ATOM   996  C CA  . VAL A 1 188  ? 120.319 97.176  73.630  1.00 84.75  ? 147  VAL A CA  1 
ATOM   997  C C   . VAL A 1 188  ? 121.123 97.486  74.890  1.00 84.75  ? 147  VAL A C   1 
ATOM   998  O O   . VAL A 1 188  ? 120.792 97.031  75.993  1.00 84.75  ? 147  VAL A O   1 
ATOM   999  C CB  . VAL A 1 188  ? 120.969 96.053  72.805  1.00 84.75  ? 147  VAL A CB  1 
ATOM   1000 C CG1 . VAL A 1 188  ? 121.250 94.850  73.680  1.00 84.75  ? 147  VAL A CG1 1 
ATOM   1001 C CG2 . VAL A 1 188  ? 120.072 95.666  71.645  1.00 84.75  ? 147  VAL A CG2 1 
ATOM   1002 N N   . VAL A 1 189  ? 122.201 98.257  74.744  1.00 83.45  ? 148  VAL A N   1 
ATOM   1003 C CA  . VAL A 1 189  ? 123.019 98.602  75.907  1.00 83.45  ? 148  VAL A CA  1 
ATOM   1004 C C   . VAL A 1 189  ? 122.224 99.470  76.879  1.00 83.45  ? 148  VAL A C   1 
ATOM   1005 O O   . VAL A 1 189  ? 122.280 99.287  78.103  1.00 83.45  ? 148  VAL A O   1 
ATOM   1006 C CB  . VAL A 1 189  ? 124.322 99.289  75.463  1.00 83.45  ? 148  VAL A CB  1 
ATOM   1007 C CG1 . VAL A 1 189  ? 125.177 99.637  76.671  1.00 83.45  ? 148  VAL A CG1 1 
ATOM   1008 C CG2 . VAL A 1 189  ? 125.088 98.392  74.507  1.00 83.45  ? 148  VAL A CG2 1 
ATOM   1009 N N   . PHE A 1 190  ? 121.468 100.433 76.352  1.00 81.75  ? 149  PHE A N   1 
ATOM   1010 C CA  . PHE A 1 190  ? 120.617 101.233 77.224  1.00 81.75  ? 149  PHE A CA  1 
ATOM   1011 C C   . PHE A 1 190  ? 119.561 100.367 77.896  1.00 81.75  ? 149  PHE A C   1 
ATOM   1012 O O   . PHE A 1 190  ? 119.181 100.617 79.044  1.00 81.75  ? 149  PHE A O   1 
ATOM   1013 C CB  . PHE A 1 190  ? 119.961 102.365 76.440  1.00 81.75  ? 149  PHE A CB  1 
ATOM   1014 C CG  . PHE A 1 190  ? 118.994 103.171 77.253  1.00 81.75  ? 149  PHE A CG  1 
ATOM   1015 C CD1 . PHE A 1 190  ? 119.449 104.004 78.260  1.00 81.75  ? 149  PHE A CD1 1 
ATOM   1016 C CD2 . PHE A 1 190  ? 117.633 103.087 77.021  1.00 81.75  ? 149  PHE A CD2 1 
ATOM   1017 C CE1 . PHE A 1 190  ? 118.565 104.745 79.017  1.00 81.75  ? 149  PHE A CE1 1 
ATOM   1018 C CE2 . PHE A 1 190  ? 116.742 103.827 77.775  1.00 81.75  ? 149  PHE A CE2 1 
ATOM   1019 C CZ  . PHE A 1 190  ? 117.209 104.657 78.774  1.00 81.75  ? 149  PHE A CZ  1 
ATOM   1020 N N   . ALA A 1 191  ? 119.076 99.341  77.196  1.00 78.35  ? 150  ALA A N   1 
ATOM   1021 C CA  . ALA A 1 191  ? 118.088 98.444  77.780  1.00 78.35  ? 150  ALA A CA  1 
ATOM   1022 C C   . ALA A 1 191  ? 118.687 97.645  78.926  1.00 78.35  ? 150  ALA A C   1 
ATOM   1023 O O   . ALA A 1 191  ? 118.012 97.366  79.920  1.00 78.35  ? 150  ALA A O   1 
ATOM   1024 C CB  . ALA A 1 191  ? 117.523 97.514  76.707  1.00 78.35  ? 150  ALA A CB  1 
ATOM   1025 N N   . ILE A 1 192  ? 119.954 97.252  78.801  1.00 71.87  ? 151  ILE A N   1 
ATOM   1026 C CA  . ILE A 1 192  ? 120.580 96.549  79.919  1.00 71.87  ? 151  ILE A CA  1 
ATOM   1027 C C   . ILE A 1 192  ? 120.834 97.515  81.075  1.00 71.87  ? 151  ILE A C   1 
ATOM   1028 O O   . ILE A 1 192  ? 120.762 97.129  82.244  1.00 71.87  ? 151  ILE A O   1 
ATOM   1029 C CB  . ILE A 1 192  ? 121.859 95.810  79.474  1.00 71.87  ? 151  ILE A CB  1 
ATOM   1030 C CG1 . ILE A 1 192  ? 122.141 94.645  80.418  1.00 71.87  ? 151  ILE A CG1 1 
ATOM   1031 C CG2 . ILE A 1 192  ? 123.066 96.717  79.484  1.00 71.87  ? 151  ILE A CG2 1 
ATOM   1032 C CD1 . ILE A 1 192  ? 123.168 93.680  79.892  1.00 71.87  ? 151  ILE A CD1 1 
ATOM   1033 N N   . ASN A 1 193  ? 121.084 98.791  80.781  1.00 76.35  ? 152  ASN A N   1 
ATOM   1034 C CA  . ASN A 1 193  ? 121.116 99.777  81.861  1.00 76.35  ? 152  ASN A CA  1 
ATOM   1035 C C   . ASN A 1 193  ? 119.764 99.855  82.571  1.00 76.35  ? 152  ASN A C   1 
ATOM   1036 O O   . ASN A 1 193  ? 119.687 99.839  83.808  1.00 76.35  ? 152  ASN A O   1 
ATOM   1037 C CB  . ASN A 1 193  ? 121.510 101.146 81.307  1.00 76.35  ? 152  ASN A CB  1 
ATOM   1038 C CG  . ASN A 1 193  ? 121.759 102.167 82.398  1.00 76.35  ? 152  ASN A CG  1 
ATOM   1039 O OD1 . ASN A 1 193  ? 121.613 101.877 83.584  1.00 76.35  ? 152  ASN A OD1 1 
ATOM   1040 N ND2 . ASN A 1 193  ? 122.128 103.377 81.998  1.00 76.35  ? 152  ASN A ND2 1 
ATOM   1041 N N   . THR A 1 194  ? 118.682 99.915  81.793  1.00 74.35  ? 153  THR A N   1 
ATOM   1042 C CA  . THR A 1 194  ? 117.351 100.044 82.373  1.00 74.35  ? 153  THR A CA  1 
ATOM   1043 C C   . THR A 1 194  ? 116.963 98.799  83.158  1.00 74.35  ? 153  THR A C   1 
ATOM   1044 O O   . THR A 1 194  ? 116.286 98.892  84.183  1.00 74.35  ? 153  THR A O   1 
ATOM   1045 C CB  . THR A 1 194  ? 116.314 100.329 81.288  1.00 74.35  ? 153  THR A CB  1 
ATOM   1046 O OG1 . THR A 1 194  ? 116.277 99.242  80.357  1.00 74.35  ? 153  THR A OG1 1 
ATOM   1047 C CG2 . THR A 1 194  ? 116.643 101.618 80.562  1.00 74.35  ? 153  THR A CG2 1 
ATOM   1048 N N   . ASP A 1 195  ? 117.370 97.619  82.693  1.00 71.28  ? 154  ASP A N   1 
ATOM   1049 C CA  . ASP A 1 195  ? 116.994 96.421  83.430  1.00 71.28  ? 154  ASP A CA  1 
ATOM   1050 C C   . ASP A 1 195  ? 117.831 96.291  84.690  1.00 71.28  ? 154  ASP A C   1 
ATOM   1051 O O   . ASP A 1 195  ? 117.358 95.763  85.701  1.00 71.28  ? 154  ASP A O   1 
ATOM   1052 C CB  . ASP A 1 195  ? 117.103 95.171  82.543  1.00 71.28  ? 154  ASP A CB  1 
ATOM   1053 C CG  . ASP A 1 195  ? 118.525 94.674  82.313  1.00 71.28  ? 154  ASP A CG  1 
ATOM   1054 O OD1 . ASP A 1 195  ? 119.488 95.186  82.896  1.00 71.28  ? 154  ASP A OD1 1 
ATOM   1055 O OD2 . ASP A 1 195  ? 118.677 93.733  81.505  1.00 71.28  ? 154  ASP A OD2 1 
ATOM   1056 N N   . ALA A 1 196  ? 119.077 96.775  84.649  1.00 70.88  ? 155  ALA A N   1 
ATOM   1057 C CA  . ALA A 1 196  ? 119.890 96.817  85.853  1.00 70.88  ? 155  ALA A CA  1 
ATOM   1058 C C   . ALA A 1 196  ? 119.369 97.820  86.866  1.00 70.88  ? 155  ALA A C   1 
ATOM   1059 O O   . ALA A 1 196  ? 119.640 97.671  88.062  1.00 70.88  ? 155  ALA A O   1 
ATOM   1060 C CB  . ALA A 1 196  ? 121.343 97.138  85.498  1.00 70.88  ? 155  ALA A CB  1 
ATOM   1061 N N   . VAL A 1 197  ? 118.636 98.840  86.429  1.00 65.98  ? 156  VAL A N   1 
ATOM   1062 C CA  . VAL A 1 197  ? 118.200 99.841  87.396  1.00 65.98  ? 156  VAL A CA  1 
ATOM   1063 C C   . VAL A 1 197  ? 116.720 99.712  87.737  1.00 65.98  ? 156  VAL A C   1 
ATOM   1064 O O   . VAL A 1 197  ? 116.368 99.360  88.868  1.00 65.98  ? 156  VAL A O   1 
ATOM   1065 C CB  . VAL A 1 197  ? 118.516 101.257 86.885  1.00 65.98  ? 156  VAL A CB  1 
ATOM   1066 C CG1 . VAL A 1 197  ? 117.940 102.302 87.826  1.00 65.98  ? 156  VAL A CG1 1 
ATOM   1067 C CG2 . VAL A 1 197  ? 120.015 101.438 86.742  1.00 65.98  ? 156  VAL A CG2 1 
ATOM   1068 N N   . MET A 1 198  ? 115.845 99.959  86.763  1.00 62.08  ? 157  MET A N   1 
ATOM   1069 C CA  . MET A 1 198  ? 114.452 100.273 87.064  1.00 62.08  ? 157  MET A CA  1 
ATOM   1070 C C   . MET A 1 198  ? 113.648 99.043  87.472  1.00 62.08  ? 157  MET A C   1 
ATOM   1071 O O   . MET A 1 198  ? 112.896 99.077  88.452  1.00 62.08  ? 157  MET A O   1 
ATOM   1072 C CB  . MET A 1 198  ? 113.817 100.982 85.866  1.00 62.08  ? 157  MET A CB  1 
ATOM   1073 C CG  . MET A 1 198  ? 114.287 102.422 85.738  1.00 62.08  ? 157  MET A CG  1 
ATOM   1074 S SD  . MET A 1 198  ? 113.402 103.424 84.530  1.00 62.08  ? 157  MET A SD  1 
ATOM   1075 C CE  . MET A 1 198  ? 113.487 102.382 83.084  1.00 62.08  ? 157  MET A CE  1 
ATOM   1076 N N   . VAL A 1 199  ? 113.787 97.943  86.731  1.00 56.72  ? 158  VAL A N   1 
ATOM   1077 C CA  . VAL A 1 199  ? 113.024 96.738  87.059  1.00 56.72  ? 158  VAL A CA  1 
ATOM   1078 C C   . VAL A 1 199  ? 113.447 96.198  88.420  1.00 56.72  ? 158  VAL A C   1 
ATOM   1079 O O   . VAL A 1 199  ? 112.611 95.827  89.254  1.00 56.72  ? 158  VAL A O   1 
ATOM   1080 C CB  . VAL A 1 199  ? 113.190 95.679  85.956  1.00 56.72  ? 158  VAL A CB  1 
ATOM   1081 C CG1 . VAL A 1 199  ? 112.470 94.402  86.340  1.00 56.72  ? 158  VAL A CG1 1 
ATOM   1082 C CG2 . VAL A 1 199  ? 112.665 96.208  84.639  1.00 56.72  ? 158  VAL A CG2 1 
ATOM   1083 N N   . GLN A 1 200  ? 114.759 96.148  88.659  1.00 58.95  ? 159  GLN A N   1 
ATOM   1084 C CA  . GLN A 1 200  ? 115.263 95.686  89.947  1.00 58.95  ? 159  GLN A CA  1 
ATOM   1085 C C   . GLN A 1 200  ? 114.797 96.595  91.072  1.00 58.95  ? 159  GLN A C   1 
ATOM   1086 O O   . GLN A 1 200  ? 114.393 96.125  92.141  1.00 58.95  ? 159  GLN A O   1 
ATOM   1087 C CB  . GLN A 1 200  ? 116.787 95.615  89.917  1.00 58.95  ? 159  GLN A CB  1 
ATOM   1088 C CG  . GLN A 1 200  ? 117.403 95.221  91.240  1.00 58.95  ? 159  GLN A CG  1 
ATOM   1089 C CD  . GLN A 1 200  ? 118.852 94.820  91.105  1.00 58.95  ? 159  GLN A CD  1 
ATOM   1090 O OE1 . GLN A 1 200  ? 119.400 94.797  90.006  1.00 58.95  ? 159  GLN A OE1 1 
ATOM   1091 N NE2 . GLN A 1 200  ? 119.482 94.496  92.224  1.00 58.95  ? 159  GLN A NE2 1 
ATOM   1092 N N   . ASP A 1 201  ? 114.837 97.909  90.844  1.00 59.01  ? 160  ASP A N   1 
ATOM   1093 C CA  . ASP A 1 201  ? 114.422 98.856  91.867  1.00 59.01  ? 160  ASP A CA  1 
ATOM   1094 C C   . ASP A 1 201  ? 112.950 98.689  92.205  1.00 59.01  ? 160  ASP A C   1 
ATOM   1095 O O   . ASP A 1 201  ? 112.557 98.797  93.371  1.00 59.01  ? 160  ASP A O   1 
ATOM   1096 C CB  . ASP A 1 201  ? 114.716 100.278 91.393  1.00 59.01  ? 160  ASP A CB  1 
ATOM   1097 C CG  . ASP A 1 201  ? 114.386 101.319 92.433  1.00 59.01  ? 160  ASP A CG  1 
ATOM   1098 O OD1 . ASP A 1 201  ? 115.135 101.426 93.425  1.00 59.01  ? 160  ASP A OD1 1 
ATOM   1099 O OD2 . ASP A 1 201  ? 113.386 102.041 92.251  1.00 59.01  ? 160  ASP A OD2 1 
ATOM   1100 N N   . ALA A 1 202  ? 112.117 98.425  91.198  1.00 52.93  ? 161  ALA A N   1 
ATOM   1101 C CA  . ALA A 1 202  ? 110.691 98.280  91.462  1.00 52.93  ? 161  ALA A CA  1 
ATOM   1102 C C   . ALA A 1 202  ? 110.379 96.972  92.170  1.00 52.93  ? 161  ALA A C   1 
ATOM   1103 O O   . ALA A 1 202  ? 109.583 96.948  93.114  1.00 52.93  ? 161  ALA A O   1 
ATOM   1104 C CB  . ALA A 1 202  ? 109.897 98.374  90.167  1.00 52.93  ? 161  ALA A CB  1 
ATOM   1105 N N   . ILE A 1 203  ? 110.984 95.865  91.732  1.00 51.83  ? 162  ILE A N   1 
ATOM   1106 C CA  . ILE A 1 203  ? 110.634 94.569  92.304  1.00 51.83  ? 162  ILE A CA  1 
ATOM   1107 C C   . ILE A 1 203  ? 111.433 94.244  93.553  1.00 51.83  ? 162  ILE A C   1 
ATOM   1108 O O   . ILE A 1 203  ? 111.207 93.190  94.160  1.00 51.83  ? 162  ILE A O   1 
ATOM   1109 C CB  . ILE A 1 203  ? 110.784 93.430  91.277  1.00 51.83  ? 162  ILE A CB  1 
ATOM   1110 C CG1 . ILE A 1 203  ? 112.258 93.110  91.035  1.00 51.83  ? 162  ILE A CG1 1 
ATOM   1111 C CG2 . ILE A 1 203  ? 110.086 93.786  89.982  1.00 51.83  ? 162  ILE A CG2 1 
ATOM   1112 C CD1 . ILE A 1 203  ? 112.474 92.026  90.013  1.00 51.83  ? 162  ILE A CD1 1 
ATOM   1113 N N   . SER A 1 204  ? 112.353 95.111  93.967  1.00 53.74  ? 163  SER A N   1 
ATOM   1114 C CA  . SER A 1 204  ? 113.130 94.845  95.166  1.00 53.74  ? 163  SER A CA  1 
ATOM   1115 C C   . SER A 1 204  ? 112.833 95.782  96.324  1.00 53.74  ? 163  SER A C   1 
ATOM   1116 O O   . SER A 1 204  ? 112.429 95.309  97.382  1.00 53.74  ? 163  SER A O   1 
ATOM   1117 C CB  . SER A 1 204  ? 114.633 94.915  94.860  1.00 53.74  ? 163  SER A CB  1 
ATOM   1118 O OG  . SER A 1 204  ? 115.030 96.242  94.572  1.00 53.74  ? 163  SER A OG  1 
ATOM   1119 N N   . GLU A 1 205  ? 112.990 97.091  96.152  1.00 53.44  ? 164  GLU A N   1 
ATOM   1120 C CA  . GLU A 1 205  ? 112.839 98.002  97.280  1.00 53.44  ? 164  GLU A CA  1 
ATOM   1121 C C   . GLU A 1 205  ? 111.502 98.726  97.242  1.00 53.44  ? 164  GLU A C   1 
ATOM   1122 O O   . GLU A 1 205  ? 110.858 98.902  98.279  1.00 53.44  ? 164  GLU A O   1 
ATOM   1123 C CB  . GLU A 1 205  ? 113.980 99.018  97.302  1.00 53.44  ? 164  GLU A CB  1 
ATOM   1124 C CG  . GLU A 1 205  ? 115.336 98.421  97.621  1.00 53.44  ? 164  GLU A CG  1 
ATOM   1125 C CD  . GLU A 1 205  ? 115.445 97.953  99.057  1.00 53.44  ? 164  GLU A CD  1 
ATOM   1126 O OE1 . GLU A 1 205  ? 114.822 98.582  99.936  1.00 53.44  ? 164  GLU A OE1 1 
ATOM   1127 O OE2 . GLU A 1 205  ? 116.155 96.958  99.308  1.00 53.44  ? 164  GLU A OE2 1 
ATOM   1128 N N   . LYS A 1 206  ? 111.077 99.150  96.053  1.00 50.59  ? 165  LYS A N   1 
ATOM   1129 C CA  . LYS A 1 206  ? 109.865 99.952  95.944  1.00 50.59  ? 165  LYS A CA  1 
ATOM   1130 C C   . LYS A 1 206  ? 108.634 99.159  96.358  1.00 50.59  ? 165  LYS A C   1 
ATOM   1131 O O   . LYS A 1 206  ? 107.698 99.712  96.945  1.00 50.59  ? 165  LYS A O   1 
ATOM   1132 C CB  . LYS A 1 206  ? 109.718 100.481 94.519  1.00 50.59  ? 165  LYS A CB  1 
ATOM   1133 C CG  . LYS A 1 206  ? 110.760 101.517 94.136  1.00 50.59  ? 165  LYS A CG  1 
ATOM   1134 C CD  . LYS A 1 206  ? 111.032 102.489 95.266  1.00 50.59  ? 165  LYS A CD  1 
ATOM   1135 C CE  . LYS A 1 206  ? 112.440 103.051 95.183  1.00 50.59  ? 165  LYS A CE  1 
ATOM   1136 N NZ  . LYS A 1 206  ? 112.748 103.959 96.319  1.00 50.59  ? 165  LYS A NZ  1 
ATOM   1137 N N   . LEU A 1 207  ? 108.610 97.860  96.061  1.00 46.24  ? 166  LEU A N   1 
ATOM   1138 C CA  . LEU A 1 207  ? 107.462 97.040  96.434  1.00 46.24  ? 166  LEU A CA  1 
ATOM   1139 C C   . LEU A 1 207  ? 107.363 96.887  97.946  1.00 46.24  ? 166  LEU A C   1 
ATOM   1140 O O   . LEU A 1 207  ? 106.280 97.028  98.533  1.00 46.24  ? 166  LEU A O   1 
ATOM   1141 C CB  . LEU A 1 207  ? 107.558 95.673  95.760  1.00 46.24  ? 166  LEU A CB  1 
ATOM   1142 C CG  . LEU A 1 207  ? 106.297 94.816  95.796  1.00 46.24  ? 166  LEU A CG  1 
ATOM   1143 C CD1 . LEU A 1 207  ? 105.092 95.625  95.364  1.00 46.24  ? 166  LEU A CD1 1 
ATOM   1144 C CD2 . LEU A 1 207  ? 106.467 93.599  94.915  1.00 46.24  ? 166  LEU A CD2 1 
ATOM   1145 N N   . GLY A 1 208  ? 108.489 96.588  98.596  1.00 44.92  ? 167  GLY A N   1 
ATOM   1146 C CA  . GLY A 1 208  ? 108.485 96.474  100.043 1.00 44.92  ? 167  GLY A CA  1 
ATOM   1147 C C   . GLY A 1 208  ? 108.089 97.772  100.718 1.00 44.92  ? 167  GLY A C   1 
ATOM   1148 O O   . GLY A 1 208  ? 107.316 97.777  101.676 1.00 44.92  ? 167  GLY A O   1 
ATOM   1149 N N   . ASN A 1 209  ? 108.609 98.893  100.217 1.00 44.88  ? 168  ASN A N   1 
ATOM   1150 C CA  . ASN A 1 209  ? 108.242 100.188 100.774 1.00 44.88  ? 168  ASN A CA  1 
ATOM   1151 C C   . ASN A 1 209  ? 106.766 100.489 100.555 1.00 44.88  ? 168  ASN A C   1 
ATOM   1152 O O   . ASN A 1 209  ? 106.113 101.070 101.425 1.00 44.88  ? 168  ASN A O   1 
ATOM   1153 C CB  . ASN A 1 209  ? 109.109 101.290 100.173 1.00 44.88  ? 168  ASN A CB  1 
ATOM   1154 C CG  . ASN A 1 209  ? 110.535 101.234 100.661 1.00 44.88  ? 168  ASN A CG  1 
ATOM   1155 O OD1 . ASN A 1 209  ? 110.904 100.350 101.429 1.00 44.88  ? 168  ASN A OD1 1 
ATOM   1156 N ND2 . ASN A 1 209  ? 111.346 102.188 100.226 1.00 44.88  ? 168  ASN A ND2 1 
ATOM   1157 N N   . PHE A 1 210  ? 106.225 100.118 99.396  1.00 41.22  ? 169  PHE A N   1 
ATOM   1158 C CA  . PHE A 1 210  ? 104.803 100.331 99.149  1.00 41.22  ? 169  PHE A CA  1 
ATOM   1159 C C   . PHE A 1 210  ? 103.955 99.553  100.146 1.00 41.22  ? 169  PHE A C   1 
ATOM   1160 O O   . PHE A 1 210  ? 103.000 100.089 100.719 1.00 41.22  ? 169  PHE A O   1 
ATOM   1161 C CB  . PHE A 1 210  ? 104.450 99.921  97.724  1.00 41.22  ? 169  PHE A CB  1 
ATOM   1162 C CG  . PHE A 1 210  ? 103.009 100.126 97.379  1.00 41.22  ? 169  PHE A CG  1 
ATOM   1163 C CD1 . PHE A 1 210  ? 102.499 101.398 97.214  1.00 41.22  ? 169  PHE A CD1 1 
ATOM   1164 C CD2 . PHE A 1 210  ? 102.159 99.049  97.245  1.00 41.22  ? 169  PHE A CD2 1 
ATOM   1165 C CE1 . PHE A 1 210  ? 101.174 101.589 96.902  1.00 41.22  ? 169  PHE A CE1 1 
ATOM   1166 C CE2 . PHE A 1 210  ? 100.831 99.234  96.936  1.00 41.22  ? 169  PHE A CE2 1 
ATOM   1167 C CZ  . PHE A 1 210  ? 100.339 100.506 96.764  1.00 41.22  ? 169  PHE A CZ  1 
ATOM   1168 N N   . ILE A 1 211  ? 104.293 98.281  100.365 1.00 41.82  ? 170  ILE A N   1 
ATOM   1169 C CA  . ILE A 1 211  ? 103.555 97.481  101.340 1.00 41.82  ? 170  ILE A CA  1 
ATOM   1170 C C   . ILE A 1 211  ? 103.689 98.084  102.731 1.00 41.82  ? 170  ILE A C   1 
ATOM   1171 O O   . ILE A 1 211  ? 102.712 98.179  103.485 1.00 41.82  ? 170  ILE A O   1 
ATOM   1172 C CB  . ILE A 1 211  ? 104.033 96.019  101.313 1.00 41.82  ? 170  ILE A CB  1 
ATOM   1173 C CG1 . ILE A 1 211  ? 103.868 95.426  99.917  1.00 41.82  ? 170  ILE A CG1 1 
ATOM   1174 C CG2 . ILE A 1 211  ? 103.273 95.194  102.331 1.00 41.82  ? 170  ILE A CG2 1 
ATOM   1175 C CD1 . ILE A 1 211  ? 104.489 94.063  99.769  1.00 41.82  ? 170  ILE A CD1 1 
ATOM   1176 N N   . HIS A 1 212  ? 104.901 98.510  103.084 1.00 43.34  ? 171  HIS A N   1 
ATOM   1177 C CA  . HIS A 1 212  ? 105.157 99.067  104.406 1.00 43.34  ? 171  HIS A CA  1 
ATOM   1178 C C   . HIS A 1 212  ? 104.343 100.335 104.635 1.00 43.34  ? 171  HIS A C   1 
ATOM   1179 O O   . HIS A 1 212  ? 103.771 100.535 105.711 1.00 43.34  ? 171  HIS A O   1 
ATOM   1180 C CB  . HIS A 1 212  ? 106.654 99.335  104.548 1.00 43.34  ? 171  HIS A CB  1 
ATOM   1181 C CG  . HIS A 1 212  ? 107.013 100.214 105.701 1.00 43.34  ? 171  HIS A CG  1 
ATOM   1182 N ND1 . HIS A 1 212  ? 107.476 101.500 105.537 1.00 43.34  ? 171  HIS A ND1 1 
ATOM   1183 C CD2 . HIS A 1 212  ? 107.016 99.980  107.032 1.00 43.34  ? 171  HIS A CD2 1 
ATOM   1184 C CE1 . HIS A 1 212  ? 107.726 102.029 106.720 1.00 43.34  ? 171  HIS A CE1 1 
ATOM   1185 N NE2 . HIS A 1 212  ? 107.455 101.127 107.644 1.00 43.34  ? 171  HIS A NE2 1 
ATOM   1186 N N   . TYR A 1 213  ? 104.259 101.196 103.621 1.00 44.71  ? 172  TYR A N   1 
ATOM   1187 C CA  . TYR A 1 213  ? 103.552 102.460 103.790 1.00 44.71  ? 172  TYR A CA  1 
ATOM   1188 C C   . TYR A 1 213  ? 102.041 102.268 103.750 1.00 44.71  ? 172  TYR A C   1 
ATOM   1189 O O   . TYR A 1 213  ? 101.308 102.979 104.444 1.00 44.71  ? 172  TYR A O   1 
ATOM   1190 C CB  . TYR A 1 213  ? 104.014 103.460 102.736 1.00 44.71  ? 172  TYR A CB  1 
ATOM   1191 C CG  . TYR A 1 213  ? 105.421 103.940 102.984 1.00 44.71  ? 172  TYR A CG  1 
ATOM   1192 C CD1 . TYR A 1 213  ? 105.893 104.113 104.276 1.00 44.71  ? 172  TYR A CD1 1 
ATOM   1193 C CD2 . TYR A 1 213  ? 106.281 104.212 101.934 1.00 44.71  ? 172  TYR A CD2 1 
ATOM   1194 C CE1 . TYR A 1 213  ? 107.177 104.545 104.515 1.00 44.71  ? 172  TYR A CE1 1 
ATOM   1195 C CE2 . TYR A 1 213  ? 107.569 104.643 102.164 1.00 44.71  ? 172  TYR A CE2 1 
ATOM   1196 C CZ  . TYR A 1 213  ? 108.011 104.806 103.458 1.00 44.71  ? 172  TYR A CZ  1 
ATOM   1197 O OH  . TYR A 1 213  ? 109.292 105.238 103.695 1.00 44.71  ? 172  TYR A OH  1 
ATOM   1198 N N   . MET A 1 214  ? 101.551 101.305 102.965 1.00 41.12  ? 173  MET A N   1 
ATOM   1199 C CA  . MET A 1 214  ? 100.142 100.934 103.070 1.00 41.12  ? 173  MET A CA  1 
ATOM   1200 C C   . MET A 1 214  ? 99.808  100.446 104.473 1.00 41.12  ? 173  MET A C   1 
ATOM   1201 O O   . MET A 1 214  ? 98.780  100.828 105.050 1.00 41.12  ? 173  MET A O   1 
ATOM   1202 C CB  . MET A 1 214  ? 99.796  99.860  102.040 1.00 41.12  ? 173  MET A CB  1 
ATOM   1203 C CG  . MET A 1 214  ? 99.571  100.367 100.638 1.00 41.12  ? 173  MET A CG  1 
ATOM   1204 S SD  . MET A 1 214  ? 98.532  101.834 100.636 1.00 41.12  ? 173  MET A SD  1 
ATOM   1205 C CE  . MET A 1 214  ? 99.646  103.034 99.942  1.00 41.12  ? 173  MET A CE  1 
ATOM   1206 N N   . ALA A 1 215  ? 100.666 99.596  105.037 1.00 42.17  ? 174  ALA A N   1 
ATOM   1207 C CA  . ALA A 1 215  ? 100.427 99.099  106.385 1.00 42.17  ? 174  ALA A CA  1 
ATOM   1208 C C   . ALA A 1 215  ? 100.431 100.241 107.390 1.00 42.17  ? 174  ALA A C   1 
ATOM   1209 O O   . ALA A 1 215  ? 99.564  100.310 108.268 1.00 42.17  ? 174  ALA A O   1 
ATOM   1210 C CB  . ALA A 1 215  ? 101.477 98.055  106.754 1.00 42.17  ? 174  ALA A CB  1 
ATOM   1211 N N   . THR A 1 216  ? 101.393 101.157 107.265 1.00 41.40  ? 175  THR A N   1 
ATOM   1212 C CA  . THR A 1 216  ? 101.467 102.284 108.189 1.00 41.40  ? 175  THR A CA  1 
ATOM   1213 C C   . THR A 1 216  ? 100.229 103.163 108.084 1.00 41.40  ? 175  THR A C   1 
ATOM   1214 O O   . THR A 1 216  ? 99.655  103.565 109.097 1.00 41.40  ? 175  THR A O   1 
ATOM   1215 C CB  . THR A 1 216  ? 102.727 103.106 107.926 1.00 41.40  ? 175  THR A CB  1 
ATOM   1216 O OG1 . THR A 1 216  ? 103.882 102.291 108.138 1.00 41.40  ? 175  THR A OG1 1 
ATOM   1217 C CG2 . THR A 1 216  ? 102.788 104.282 108.866 1.00 41.40  ? 175  THR A CG2 1 
ATOM   1218 N N   . PHE A 1 217  ? 99.790  103.452 106.859 1.00 41.26  ? 176  PHE A N   1 
ATOM   1219 C CA  . PHE A 1 217  ? 98.611  104.289 106.662 1.00 41.26  ? 176  PHE A CA  1 
ATOM   1220 C C   . PHE A 1 217  ? 97.371  103.653 107.277 1.00 41.26  ? 176  PHE A C   1 
ATOM   1221 O O   . PHE A 1 217  ? 96.653  104.290 108.061 1.00 41.26  ? 176  PHE A O   1 
ATOM   1222 C CB  . PHE A 1 217  ? 98.415  104.538 105.169 1.00 41.26  ? 176  PHE A CB  1 
ATOM   1223 C CG  . PHE A 1 217  ? 97.007  104.866 104.781 1.00 41.26  ? 176  PHE A CG  1 
ATOM   1224 C CD1 . PHE A 1 217  ? 96.430  106.066 105.149 1.00 41.26  ? 176  PHE A CD1 1 
ATOM   1225 C CD2 . PHE A 1 217  ? 96.262  103.975 104.033 1.00 41.26  ? 176  PHE A CD2 1 
ATOM   1226 C CE1 . PHE A 1 217  ? 95.135  106.367 104.779 1.00 41.26  ? 176  PHE A CE1 1 
ATOM   1227 C CE2 . PHE A 1 217  ? 94.968  104.271 103.664 1.00 41.26  ? 176  PHE A CE2 1 
ATOM   1228 C CZ  . PHE A 1 217  ? 94.404  105.468 104.039 1.00 41.26  ? 176  PHE A CZ  1 
ATOM   1229 N N   . VAL A 1 218  ? 97.114  102.386 106.946 1.00 41.20  ? 177  VAL A N   1 
ATOM   1230 C CA  . VAL A 1 218  ? 95.913  101.721 107.444 1.00 41.20  ? 177  VAL A CA  1 
ATOM   1231 C C   . VAL A 1 218  ? 95.954  101.608 108.963 1.00 41.20  ? 177  VAL A C   1 
ATOM   1232 O O   . VAL A 1 218  ? 94.967  101.897 109.651 1.00 41.20  ? 177  VAL A O   1 
ATOM   1233 C CB  . VAL A 1 218  ? 95.747  100.344 106.779 1.00 41.20  ? 177  VAL A CB  1 
ATOM   1234 C CG1 . VAL A 1 218  ? 94.631  99.569  107.446 1.00 41.20  ? 177  VAL A CG1 1 
ATOM   1235 C CG2 . VAL A 1 218  ? 95.463  100.511 105.300 1.00 41.20  ? 177  VAL A CG2 1 
ATOM   1236 N N   . SER A 1 219  ? 97.099  101.194 109.511 1.00 39.13  ? 178  SER A N   1 
ATOM   1237 C CA  . SER A 1 219  ? 97.208  101.021 110.953 1.00 39.13  ? 178  SER A CA  1 
ATOM   1238 C C   . SER A 1 219  ? 97.055  102.347 111.683 1.00 39.13  ? 178  SER A C   1 
ATOM   1239 O O   . SER A 1 219  ? 96.401  102.417 112.728 1.00 39.13  ? 178  SER A O   1 
ATOM   1240 C CB  . SER A 1 219  ? 98.542  100.366 111.300 1.00 39.13  ? 178  SER A CB  1 
ATOM   1241 O OG  . SER A 1 219  ? 98.641  100.139 112.692 1.00 39.13  ? 178  SER A OG  1 
ATOM   1242 N N   . GLY A 1 220  ? 97.658  103.412 111.152 1.00 40.70  ? 179  GLY A N   1 
ATOM   1243 C CA  . GLY A 1 220  ? 97.531  104.709 111.791 1.00 40.70  ? 179  GLY A CA  1 
ATOM   1244 C C   . GLY A 1 220  ? 96.102  105.203 111.801 1.00 40.70  ? 179  GLY A C   1 
ATOM   1245 O O   . GLY A 1 220  ? 95.614  105.708 112.815 1.00 40.70  ? 179  GLY A O   1 
ATOM   1246 N N   . PHE A 1 221  ? 95.405  105.051 110.677 1.00 40.27  ? 180  PHE A N   1 
ATOM   1247 C CA  . PHE A 1 221  ? 94.013  105.481 110.631 1.00 40.27  ? 180  PHE A CA  1 
ATOM   1248 C C   . PHE A 1 221  ? 93.159  104.674 111.599 1.00 40.27  ? 180  PHE A C   1 
ATOM   1249 O O   . PHE A 1 221  ? 92.329  105.234 112.327 1.00 40.27  ? 180  PHE A O   1 
ATOM   1250 C CB  . PHE A 1 221  ? 93.486  105.378 109.207 1.00 40.27  ? 180  PHE A CB  1 
ATOM   1251 C CG  . PHE A 1 221  ? 93.554  106.667 108.458 1.00 40.27  ? 180  PHE A CG  1 
ATOM   1252 C CD1 . PHE A 1 221  ? 94.775  107.194 108.085 1.00 40.27  ? 180  PHE A CD1 1 
ATOM   1253 C CD2 . PHE A 1 221  ? 92.404  107.355 108.132 1.00 40.27  ? 180  PHE A CD2 1 
ATOM   1254 C CE1 . PHE A 1 221  ? 94.850  108.386 107.401 1.00 40.27  ? 180  PHE A CE1 1 
ATOM   1255 C CE2 . PHE A 1 221  ? 92.473  108.546 107.444 1.00 40.27  ? 180  PHE A CE2 1 
ATOM   1256 C CZ  . PHE A 1 221  ? 93.698  109.062 107.078 1.00 40.27  ? 180  PHE A CZ  1 
ATOM   1257 N N   . ILE A 1 222  ? 93.367  103.357 111.644 1.00 38.72  ? 181  ILE A N   1 
ATOM   1258 C CA  . ILE A 1 222  ? 92.585  102.516 112.548 1.00 38.72  ? 181  ILE A CA  1 
ATOM   1259 C C   . ILE A 1 222  ? 92.837  102.913 113.996 1.00 38.72  ? 181  ILE A C   1 
ATOM   1260 O O   . ILE A 1 222  ? 91.899  103.079 114.785 1.00 38.72  ? 181  ILE A O   1 
ATOM   1261 C CB  . ILE A 1 222  ? 92.903  101.030 112.308 1.00 38.72  ? 181  ILE A CB  1 
ATOM   1262 C CG1 . ILE A 1 222  ? 92.343  100.580 110.960 1.00 38.72  ? 181  ILE A CG1 1 
ATOM   1263 C CG2 . ILE A 1 222  ? 92.351  100.178 113.433 1.00 38.72  ? 181  ILE A CG2 1 
ATOM   1264 C CD1 . ILE A 1 222  ? 90.883  100.908 110.776 1.00 38.72  ? 181  ILE A CD1 1 
ATOM   1265 N N   . VAL A 1 223  ? 94.109  103.080 114.365 1.00 40.16  ? 182  VAL A N   1 
ATOM   1266 C CA  . VAL A 1 223  ? 94.451  103.422 115.743 1.00 40.16  ? 182  VAL A CA  1 
ATOM   1267 C C   . VAL A 1 223  ? 93.844  104.765 116.123 1.00 40.16  ? 182  VAL A C   1 
ATOM   1268 O O   . VAL A 1 223  ? 93.196  104.900 117.167 1.00 40.16  ? 182  VAL A O   1 
ATOM   1269 C CB  . VAL A 1 223  ? 95.977  103.421 115.930 1.00 40.16  ? 182  VAL A CB  1 
ATOM   1270 C CG1 . VAL A 1 223  ? 96.356  104.160 117.195 1.00 40.16  ? 182  VAL A CG1 1 
ATOM   1271 C CG2 . VAL A 1 223  ? 96.500  102.002 115.970 1.00 40.16  ? 182  VAL A CG2 1 
ATOM   1272 N N   . GLY A 1 224  ? 94.016  105.770 115.264 1.00 36.61  ? 183  GLY A N   1 
ATOM   1273 C CA  . GLY A 1 224  ? 93.503  107.090 115.585 1.00 36.61  ? 183  GLY A CA  1 
ATOM   1274 C C   . GLY A 1 224  ? 91.995  107.110 115.725 1.00 36.61  ? 183  GLY A C   1 
ATOM   1275 O O   . GLY A 1 224  ? 91.452  107.712 116.658 1.00 36.61  ? 183  GLY A O   1 
ATOM   1276 N N   . PHE A 1 225  ? 91.294  106.450 114.800 1.00 42.00  ? 184  PHE A N   1 
ATOM   1277 C CA  . PHE A 1 225  ? 89.838  106.476 114.848 1.00 42.00  ? 184  PHE A CA  1 
ATOM   1278 C C   . PHE A 1 225  ? 89.309  105.719 116.055 1.00 42.00  ? 184  PHE A C   1 
ATOM   1279 O O   . PHE A 1 225  ? 88.493  106.260 116.814 1.00 42.00  ? 184  PHE A O   1 
ATOM   1280 C CB  . PHE A 1 225  ? 89.260  105.924 113.550 1.00 42.00  ? 184  PHE A CB  1 
ATOM   1281 C CG  . PHE A 1 225  ? 89.120  106.958 112.479 1.00 42.00  ? 184  PHE A CG  1 
ATOM   1282 C CD1 . PHE A 1 225  ? 88.227  108.002 112.625 1.00 42.00  ? 184  PHE A CD1 1 
ATOM   1283 C CD2 . PHE A 1 225  ? 89.904  106.910 111.341 1.00 42.00  ? 184  PHE A CD2 1 
ATOM   1284 C CE1 . PHE A 1 225  ? 88.101  108.966 111.648 1.00 42.00  ? 184  PHE A CE1 1 
ATOM   1285 C CE2 . PHE A 1 225  ? 89.784  107.871 110.360 1.00 42.00  ? 184  PHE A CE2 1 
ATOM   1286 C CZ  . PHE A 1 225  ? 88.881  108.900 110.515 1.00 42.00  ? 184  PHE A CZ  1 
ATOM   1287 N N   . THR A 1 226  ? 89.805  104.497 116.281 1.00 38.50  ? 185  THR A N   1 
ATOM   1288 C CA  . THR A 1 226  ? 89.352  103.709 117.422 1.00 38.50  ? 185  THR A CA  1 
ATOM   1289 C C   . THR A 1 226  ? 89.708  104.380 118.740 1.00 38.50  ? 185  THR A C   1 
ATOM   1290 O O   . THR A 1 226  ? 89.053  104.138 119.759 1.00 38.50  ? 185  THR A O   1 
ATOM   1291 C CB  . THR A 1 226  ? 89.950  102.306 117.371 1.00 38.50  ? 185  THR A CB  1 
ATOM   1292 O OG1 . THR A 1 226  ? 91.373  102.397 117.230 1.00 38.50  ? 185  THR A OG1 1 
ATOM   1293 C CG2 . THR A 1 226  ? 89.382  101.530 116.201 1.00 38.50  ? 185  THR A CG2 1 
ATOM   1294 N N   . ALA A 1 227  ? 90.742  105.223 118.752 1.00 41.25  ? 186  ALA A N   1 
ATOM   1295 C CA  . ALA A 1 227  ? 91.048  105.955 119.978 1.00 41.25  ? 186  ALA A CA  1 
ATOM   1296 C C   . ALA A 1 227  ? 90.080  107.118 120.168 1.00 41.25  ? 186  ALA A C   1 
ATOM   1297 O O   . ALA A 1 227  ? 89.284  107.127 121.112 1.00 41.25  ? 186  ALA A O   1 
ATOM   1298 C CB  . ALA A 1 227  ? 92.500  106.440 119.953 1.00 41.25  ? 186  ALA A CB  1 
ATOM   1299 N N   . VAL A 1 228  ? 90.121  108.106 119.275 1.00 42.70  ? 187  VAL A N   1 
ATOM   1300 C CA  . VAL A 1 228  ? 89.211  109.252 119.323 1.00 42.70  ? 187  VAL A CA  1 
ATOM   1301 C C   . VAL A 1 228  ? 88.804  109.549 117.883 1.00 42.70  ? 187  VAL A C   1 
ATOM   1302 O O   . VAL A 1 228  ? 89.533  110.220 117.148 1.00 42.70  ? 187  VAL A O   1 
ATOM   1303 C CB  . VAL A 1 228  ? 89.847  110.486 119.975 1.00 42.70  ? 187  VAL A CB  1 
ATOM   1304 C CG1 . VAL A 1 228  ? 88.847  111.622 120.038 1.00 42.70  ? 187  VAL A CG1 1 
ATOM   1305 C CG2 . VAL A 1 228  ? 90.373  110.164 121.351 1.00 42.70  ? 187  VAL A CG2 1 
ATOM   1306 N N   . TRP A 1 229  ? 87.645  109.033 117.465 1.00 45.31  ? 188  TRP A N   1 
ATOM   1307 C CA  . TRP A 1 229  ? 87.168  109.317 116.114 1.00 45.31  ? 188  TRP A CA  1 
ATOM   1308 C C   . TRP A 1 229  ? 87.023  110.814 115.838 1.00 45.31  ? 188  TRP A C   1 
ATOM   1309 O O   . TRP A 1 229  ? 87.283  111.260 114.716 1.00 45.31  ? 188  TRP A O   1 
ATOM   1310 C CB  . TRP A 1 229  ? 85.849  108.593 115.848 1.00 45.31  ? 188  TRP A CB  1 
ATOM   1311 C CG  . TRP A 1 229  ? 84.706  109.049 116.674 1.00 45.31  ? 188  TRP A CG  1 
ATOM   1312 C CD1 . TRP A 1 229  ? 84.393  108.643 117.934 1.00 45.31  ? 188  TRP A CD1 1 
ATOM   1313 C CD2 . TRP A 1 229  ? 83.711  110.005 116.300 1.00 45.31  ? 188  TRP A CD2 1 
ATOM   1314 N NE1 . TRP A 1 229  ? 83.261  109.283 118.369 1.00 45.31  ? 188  TRP A NE1 1 
ATOM   1315 C CE2 . TRP A 1 229  ? 82.823  110.127 117.383 1.00 45.31  ? 188  TRP A CE2 1 
ATOM   1316 C CE3 . TRP A 1 229  ? 83.486  110.769 115.153 1.00 45.31  ? 188  TRP A CE3 1 
ATOM   1317 C CZ2 . TRP A 1 229  ? 81.729  110.984 117.355 1.00 45.31  ? 188  TRP A CZ2 1 
ATOM   1318 C CZ3 . TRP A 1 229  ? 82.399  111.618 115.128 1.00 45.31  ? 188  TRP A CZ3 1 
ATOM   1319 C CH2 . TRP A 1 229  ? 81.535  111.719 116.221 1.00 45.31  ? 188  TRP A CH2 1 
ATOM   1320 N N   . GLN A 1 230  ? 86.603  111.576 116.852 1.00 43.24  ? 189  GLN A N   1 
ATOM   1321 C CA  . GLN A 1 230  ? 86.380  113.036 116.666 1.00 43.24  ? 189  GLN A CA  1 
ATOM   1322 C C   . GLN A 1 230  ? 87.700  113.705 116.270 1.00 43.24  ? 189  GLN A C   1 
ATOM   1323 O O   . GLN A 1 230  ? 87.756  114.307 115.179 1.00 43.24  ? 189  GLN A O   1 
ATOM   1324 C CB  . GLN A 1 230  ? 85.834  113.652 117.955 1.00 43.24  ? 189  GLN A CB  1 
ATOM   1325 C CG  . GLN A 1 230  ? 84.526  113.030 118.416 1.00 43.24  ? 189  GLN A CG  1 
ATOM   1326 C CD  . GLN A 1 230  ? 84.575  112.595 119.860 1.00 43.24  ? 189  GLN A CD  1 
ATOM   1327 O OE1 . GLN A 1 230  ? 85.587  112.750 120.542 1.00 43.24  ? 189  GLN A OE1 1 
ATOM   1328 N NE2 . GLN A 1 230  ? 83.474  112.042 120.341 1.00 43.24  ? 189  GLN A NE2 1 
ATOM   1329 N N   . LEU A 1 231  ? 88.716  113.601 117.129 1.00 41.77  ? 190  LEU A N   1 
ATOM   1330 C CA  . LEU A 1 231  ? 90.023  114.255 116.856 1.00 41.77  ? 190  LEU A CA  1 
ATOM   1331 C C   . LEU A 1 231  ? 90.643  113.645 115.594 1.00 41.77  ? 190  LEU A C   1 
ATOM   1332 O O   . LEU A 1 231  ? 91.294  114.391 114.840 1.00 41.77  ? 190  LEU A O   1 
ATOM   1333 C CB  . LEU A 1 231  ? 90.931  114.066 118.073 1.00 41.77  ? 190  LEU A CB  1 
ATOM   1334 C CG  . LEU A 1 231  ? 92.216  114.890 118.065 1.00 41.77  ? 190  LEU A CG  1 
ATOM   1335 C CD1 . LEU A 1 231  ? 91.922  116.340 117.712 1.00 41.77  ? 190  LEU A CD1 1 
ATOM   1336 C CD2 . LEU A 1 231  ? 92.902  114.812 119.417 1.00 41.77  ? 190  LEU A CD2 1 
ATOM   1337 N N   . ALA A 1 232  ? 90.442  112.342 115.374 1.00 40.60  ? 191  ALA A N   1 
ATOM   1338 C CA  . ALA A 1 232  ? 90.988  111.677 114.169 1.00 40.60  ? 191  ALA A CA  1 
ATOM   1339 C C   . ALA A 1 232  ? 90.454  112.377 112.917 1.00 40.60  ? 191  ALA A C   1 
ATOM   1340 O O   . ALA A 1 232  ? 91.258  112.645 112.008 1.00 40.60  ? 191  ALA A O   1 
ATOM   1341 C CB  . ALA A 1 232  ? 90.631  110.213 114.174 1.00 40.60  ? 191  ALA A CB  1 
ATOM   1342 N N   . LEU A 1 233  ? 89.150  112.669 112.885 1.00 40.62  ? 192  LEU A N   1 
ATOM   1343 C CA  . LEU A 1 233  ? 88.541  113.366 111.720 1.00 40.62  ? 192  LEU A CA  1 
ATOM   1344 C C   . LEU A 1 233  ? 89.207  114.733 111.543 1.00 40.62  ? 192  LEU A C   1 
ATOM   1345 O O   . LEU A 1 233  ? 89.561  115.074 110.398 1.00 40.62  ? 192  LEU A O   1 
ATOM   1346 C CB  . LEU A 1 233  ? 87.038  113.520 111.967 1.00 40.62  ? 192  LEU A CB  1 
ATOM   1347 C CG  . LEU A 1 233  ? 86.203  112.260 111.752 1.00 40.62  ? 192  LEU A CG  1 
ATOM   1348 C CD1 . LEU A 1 233  ? 84.734  112.531 112.036 1.00 40.62  ? 192  LEU A CD1 1 
ATOM   1349 C CD2 . LEU A 1 233  ? 86.378  111.738 110.335 1.00 40.62  ? 192  LEU A CD2 1 
ATOM   1350 N N   . VAL A 1 234  ? 89.369  115.480 112.639 1.00 40.31  ? 193  VAL A N   1 
ATOM   1351 C CA  . VAL A 1 234  ? 89.997  116.833 112.567 1.00 40.31  ? 193  VAL A CA  1 
ATOM   1352 C C   . VAL A 1 234  ? 91.435  116.681 112.064 1.00 40.31  ? 193  VAL A C   1 
ATOM   1353 O O   . VAL A 1 234  ? 91.830  117.443 111.158 1.00 40.31  ? 193  VAL A O   1 
ATOM   1354 C CB  . VAL A 1 234  ? 89.951  117.542 113.934 1.00 40.31  ? 193  VAL A CB  1 
ATOM   1355 C CG1 . VAL A 1 234  ? 90.666  118.884 113.899 1.00 40.31  ? 193  VAL A CG1 1 
ATOM   1356 C CG2 . VAL A 1 234  ? 88.525  117.705 114.433 1.00 40.31  ? 193  VAL A CG2 1 
ATOM   1357 N N   . THR A 1 235  ? 92.181  115.724 112.624 1.00 39.25  ? 194  THR A N   1 
ATOM   1358 C CA  . THR A 1 235  ? 93.590  115.498 112.209 1.00 39.25  ? 194  THR A CA  1 
ATOM   1359 C C   . THR A 1 235  ? 93.612  115.042 110.748 1.00 39.25  ? 194  THR A C   1 
ATOM   1360 O O   . THR A 1 235  ? 94.532  115.454 110.016 1.00 39.25  ? 194  THR A O   1 
ATOM   1361 C CB  . THR A 1 235  ? 94.282  114.492 113.136 1.00 39.25  ? 194  THR A CB  1 
ATOM   1362 O OG1 . THR A 1 235  ? 93.953  114.826 114.485 1.00 39.25  ? 194  THR A OG1 1 
ATOM   1363 C CG2 . THR A 1 235  ? 95.784  114.473 112.964 1.00 39.25  ? 194  THR A CG2 1 
ATOM   1364 N N   . LEU A 1 236  ? 92.631  114.228 110.345 1.00 39.84  ? 195  LEU A N   1 
ATOM   1365 C CA  . LEU A 1 236  ? 92.548  113.745 108.940 1.00 39.84  ? 195  LEU A CA  1 
ATOM   1366 C C   . LEU A 1 236  ? 92.412  114.950 108.005 1.00 39.84  ? 195  LEU A C   1 
ATOM   1367 O O   . LEU A 1 236  ? 93.079  114.952 106.957 1.00 39.84  ? 195  LEU A O   1 
ATOM   1368 C CB  . LEU A 1 236  ? 91.346  112.803 108.814 1.00 39.84  ? 195  LEU A CB  1 
ATOM   1369 C CG  . LEU A 1 236  ? 90.716  112.708 107.426 1.00 39.84  ? 195  LEU A CG  1 
ATOM   1370 C CD1 . LEU A 1 236  ? 91.587  111.890 106.485 1.00 39.84  ? 195  LEU A CD1 1 
ATOM   1371 C CD2 . LEU A 1 236  ? 89.319  112.115 107.509 1.00 39.84  ? 195  LEU A CD2 1 
ATOM   1372 N N   . ALA A 1 237  ? 91.587  115.933 108.378 1.00 40.89  ? 196  ALA A N   1 
ATOM   1373 C CA  . ALA A 1 237  ? 91.408  117.149 107.550 1.00 40.89  ? 196  ALA A CA  1 
ATOM   1374 C C   . ALA A 1 237  ? 92.705  117.965 107.540 1.00 40.89  ? 196  ALA A C   1 
ATOM   1375 O O   . ALA A 1 237  ? 92.961  118.651 106.532 1.00 40.89  ? 196  ALA A O   1 
ATOM   1376 C CB  . ALA A 1 237  ? 90.251  117.958 108.078 1.00 40.89  ? 196  ALA A CB  1 
ATOM   1377 N N   . VAL A 1 238  ? 93.480  117.905 108.627 1.00 42.63  ? 197  VAL A N   1 
ATOM   1378 C CA  . VAL A 1 238  ? 94.752  118.684 108.734 1.00 42.63  ? 197  VAL A CA  1 
ATOM   1379 C C   . VAL A 1 238  ? 95.843  118.026 107.883 1.00 42.63  ? 197  VAL A C   1 
ATOM   1380 O O   . VAL A 1 238  ? 96.750  118.754 107.436 1.00 42.63  ? 197  VAL A O   1 
ATOM   1381 C CB  . VAL A 1 238  ? 95.202  118.806 110.201 1.00 42.63  ? 197  VAL A CB  1 
ATOM   1382 C CG1 . VAL A 1 238  ? 96.714  118.901 110.325 1.00 42.63  ? 197  VAL A CG1 1 
ATOM   1383 C CG2 . VAL A 1 238  ? 94.519  119.963 110.915 1.00 42.63  ? 197  VAL A CG2 1 
ATOM   1384 N N   . VAL A 1 239  ? 95.766  116.710 107.667 1.00 42.23  ? 198  VAL A N   1 
ATOM   1385 C CA  . VAL A 1 239  ? 96.851  115.985 106.932 1.00 42.23  ? 198  VAL A CA  1 
ATOM   1386 C C   . VAL A 1 239  ? 97.078  116.587 105.537 1.00 42.23  ? 198  VAL A C   1 
ATOM   1387 O O   . VAL A 1 239  ? 98.244  116.914 105.237 1.00 42.23  ? 198  VAL A O   1 
ATOM   1388 C CB  . VAL A 1 239  ? 96.564  114.471 106.856 1.00 42.23  ? 198  VAL A CB  1 
ATOM   1389 C CG1 . VAL A 1 239  ? 97.455  113.781 105.836 1.00 42.23  ? 198  VAL A CG1 1 
ATOM   1390 C CG2 . VAL A 1 239  ? 96.685  113.803 108.216 1.00 42.23  ? 198  VAL A CG2 1 
ATOM   1391 N N   . PRO A 1 240  ? 96.055  116.763 104.667 1.00 42.67  ? 199  PRO A N   1 
ATOM   1392 C CA  . PRO A 1 240  ? 96.283  117.245 103.296 1.00 42.67  ? 199  PRO A CA  1 
ATOM   1393 C C   . PRO A 1 240  ? 97.136  118.519 103.222 1.00 42.67  ? 199  PRO A C   1 
ATOM   1394 O O   . PRO A 1 240  ? 97.996  118.583 102.367 1.00 42.67  ? 199  PRO A O   1 
ATOM   1395 C CB  . PRO A 1 240  ? 94.867  117.559 102.793 1.00 42.67  ? 199  PRO A CB  1 
ATOM   1396 C CG  . PRO A 1 240  ? 93.997  116.580 103.539 1.00 42.67  ? 199  PRO A CG  1 
ATOM   1397 C CD  . PRO A 1 240  ? 94.638  116.480 104.906 1.00 42.67  ? 199  PRO A CD  1 
ATOM   1398 N N   . LEU A 1 241  ? 96.886  119.491 104.105 1.00 43.89  ? 200  LEU A N   1 
ATOM   1399 C CA  . LEU A 1 241  ? 97.624  120.783 104.042 1.00 43.89  ? 200  LEU A CA  1 
ATOM   1400 C C   . LEU A 1 241  ? 99.129  120.511 104.126 1.00 43.89  ? 200  LEU A C   1 
ATOM   1401 O O   . LEU A 1 241  ? 99.865  121.002 103.248 1.00 43.89  ? 200  LEU A O   1 
ATOM   1402 C CB  . LEU A 1 241  ? 97.165  121.674 105.199 1.00 43.89  ? 200  LEU A CB  1 
ATOM   1403 C CG  . LEU A 1 241  ? 95.704  122.115 105.152 1.00 43.89  ? 200  LEU A CG  1 
ATOM   1404 C CD1 . LEU A 1 241  ? 95.434  123.200 106.183 1.00 43.89  ? 200  LEU A CD1 1 
ATOM   1405 C CD2 . LEU A 1 241  ? 95.330  122.600 103.759 1.00 43.89  ? 200  LEU A CD2 1 
ATOM   1406 N N   . ILE A 1 242  ? 99.561  119.742 105.130 1.00 45.04  ? 201  ILE A N   1 
ATOM   1407 C CA  . ILE A 1 242  ? 101.013 119.453 105.321 1.00 45.04  ? 201  ILE A CA  1 
ATOM   1408 C C   . ILE A 1 242  ? 101.535 118.706 104.089 1.00 45.04  ? 201  ILE A C   1 
ATOM   1409 O O   . ILE A 1 242  ? 102.591 119.108 103.557 1.00 45.04  ? 201  ILE A O   1 
ATOM   1410 C CB  . ILE A 1 242  ? 101.236 118.648 106.617 1.00 45.04  ? 201  ILE A CB  1 
ATOM   1411 C CG1 . ILE A 1 242  ? 100.639 119.362 107.833 1.00 45.04  ? 201  ILE A CG1 1 
ATOM   1412 C CG2 . ILE A 1 242  ? 102.710 118.332 106.816 1.00 45.04  ? 201  ILE A CG2 1 
ATOM   1413 C CD1 . ILE A 1 242  ? 100.813 118.609 109.131 1.00 45.04  ? 201  ILE A CD1 1 
ATOM   1414 N N   . ALA A 1 243  ? 100.810 117.675 103.643 1.00 46.45  ? 202  ALA A N   1 
ATOM   1415 C CA  . ALA A 1 243  ? 101.252 116.874 102.478 1.00 46.45  ? 202  ALA A CA  1 
ATOM   1416 C C   . ALA A 1 243  ? 101.333 117.770 101.237 1.00 46.45  ? 202  ALA A C   1 
ATOM   1417 O O   . ALA A 1 243  ? 102.317 117.644 100.481 1.00 46.45  ? 202  ALA A O   1 
ATOM   1418 C CB  . ALA A 1 243  ? 100.305 115.719 102.264 1.00 46.45  ? 202  ALA A CB  1 
ATOM   1419 N N   . VAL A 1 244  ? 100.344 118.648 101.048 1.00 47.29  ? 203  VAL A N   1 
ATOM   1420 C CA  . VAL A 1 244  ? 100.313 119.541 99.852  1.00 47.29  ? 203  VAL A CA  1 
ATOM   1421 C C   . VAL A 1 244  ? 101.575 120.410 99.850  1.00 47.29  ? 203  VAL A C   1 
ATOM   1422 O O   . VAL A 1 244  ? 102.260 120.451 98.809  1.00 47.29  ? 203  VAL A O   1 
ATOM   1423 C CB  . VAL A 1 244  ? 99.040  120.409 99.838  1.00 47.29  ? 203  VAL A CB  1 
ATOM   1424 C CG1 . VAL A 1 244  ? 98.993  121.329 98.627  1.00 47.29  ? 203  VAL A CG1 1 
ATOM   1425 C CG2 . VAL A 1 244  ? 97.779  119.562 99.917  1.00 47.29  ? 203  VAL A CG2 1 
ATOM   1426 N N   . ILE A 1 245  ? 101.880 121.054 100.981 1.00 49.93  ? 204  ILE A N   1 
ATOM   1427 C CA  . ILE A 1 245  ? 103.061 121.968 101.046 1.00 49.93  ? 204  ILE A CA  1 
ATOM   1428 C C   . ILE A 1 245  ? 104.320 121.163 100.708 1.00 49.93  ? 204  ILE A C   1 
ATOM   1429 O O   . ILE A 1 245  ? 105.135 121.655 99.901  1.00 49.93  ? 204  ILE A O   1 
ATOM   1430 C CB  . ILE A 1 245  ? 103.167 122.641 102.430 1.00 49.93  ? 204  ILE A CB  1 
ATOM   1431 C CG1 . ILE A 1 245  ? 101.900 123.427 102.777 1.00 49.93  ? 204  ILE A CG1 1 
ATOM   1432 C CG2 . ILE A 1 245  ? 104.408 123.513 102.508 1.00 49.93  ? 204  ILE A CG2 1 
ATOM   1433 C CD1 . ILE A 1 245  ? 101.567 124.518 101.787 1.00 49.93  ? 204  ILE A CD1 1 
ATOM   1434 N N   . GLY A 1 246  ? 104.458 119.966 101.287 1.00 53.59  ? 205  GLY A N   1 
ATOM   1435 C CA  . GLY A 1 246  ? 105.650 119.132 101.039 1.00 53.59  ? 205  GLY A CA  1 
ATOM   1436 C C   . GLY A 1 246  ? 105.819 118.828 99.561  1.00 53.59  ? 205  GLY A C   1 
ATOM   1437 O O   . GLY A 1 246  ? 106.946 118.984 99.052  1.00 53.59  ? 205  GLY A O   1 
ATOM   1438 N N   . GLY A 1 247  ? 104.733 118.429 98.891  1.00 55.59  ? 206  GLY A N   1 
ATOM   1439 C CA  . GLY A 1 247  ? 104.793 118.122 97.448  1.00 55.59  ? 206  GLY A CA  1 
ATOM   1440 C C   . GLY A 1 247  ? 105.202 119.340 96.636  1.00 55.59  ? 206  GLY A C   1 
ATOM   1441 O O   . GLY A 1 247  ? 106.081 119.196 95.763  1.00 55.59  ? 206  GLY A O   1 
ATOM   1442 N N   . ILE A 1 248  ? 104.600 120.498 96.922  1.00 56.83  ? 207  ILE A N   1 
ATOM   1443 C CA  . ILE A 1 248  ? 104.917 121.749 96.170  1.00 56.83  ? 207  ILE A CA  1 
ATOM   1444 C C   . ILE A 1 248  ? 106.403 122.067 96.358  1.00 56.83  ? 207  ILE A C   1 
ATOM   1445 O O   . ILE A 1 248  ? 107.079 122.350 95.348  1.00 56.83  ? 207  ILE A O   1 
ATOM   1446 C CB  . ILE A 1 248  ? 104.026 122.913 96.646  1.00 56.83  ? 207  ILE A CB  1 
ATOM   1447 C CG1 . ILE A 1 248  ? 102.538 122.603 96.458  1.00 56.83  ? 207  ILE A CG1 1 
ATOM   1448 C CG2 . ILE A 1 248  ? 104.419 124.212 95.960  1.00 56.83  ? 207  ILE A CG2 1 
ATOM   1449 C CD1 . ILE A 1 248  ? 101.619 123.665 97.013  1.00 56.83  ? 207  ILE A CD1 1 
ATOM   1450 N N   . HIS A 1 249  ? 106.892 122.001 97.599  1.00 59.23  ? 208  HIS A N   1 
ATOM   1451 C CA  . HIS A 1 249  ? 108.313 122.336 97.889  1.00 59.23  ? 208  HIS A CA  1 
ATOM   1452 C C   . HIS A 1 249  ? 109.226 121.390 97.101  1.00 59.23  ? 208  HIS A C   1 
ATOM   1453 O O   . HIS A 1 249  ? 110.177 121.870 96.444  1.00 59.23  ? 208  HIS A O   1 
ATOM   1454 C CB  . HIS A 1 249  ? 108.569 122.274 99.399  1.00 59.23  ? 208  HIS A CB  1 
ATOM   1455 C CG  . HIS A 1 249  ? 109.998 122.442 99.793  1.00 59.23  ? 208  HIS A CG  1 
ATOM   1456 N ND1 . HIS A 1 249  ? 110.676 121.500 100.536 1.00 59.23  ? 208  HIS A ND1 1 
ATOM   1457 C CD2 . HIS A 1 249  ? 110.870 123.433 99.568  1.00 59.23  ? 208  HIS A CD2 1 
ATOM   1458 C CE1 . HIS A 1 249  ? 111.917 121.915 100.741 1.00 59.23  ? 208  HIS A CE1 1 
ATOM   1459 N NE2 . HIS A 1 249  ? 112.056 123.087 100.162 1.00 59.23  ? 208  HIS A NE2 1 
ATOM   1460 N N   . THR A 1 250  ? 108.933 120.087 97.147  1.00 62.55  ? 209  THR A N   1 
ATOM   1461 C CA  . THR A 1 250  ? 109.779 119.086 96.443  1.00 62.55  ? 209  THR A CA  1 
ATOM   1462 C C   . THR A 1 250  ? 109.787 119.392 94.942  1.00 62.55  ? 209  THR A C   1 
ATOM   1463 O O   . THR A 1 250  ? 110.888 119.435 94.356  1.00 62.55  ? 209  THR A O   1 
ATOM   1464 C CB  . THR A 1 250  ? 109.286 117.660 96.718  1.00 62.55  ? 209  THR A CB  1 
ATOM   1465 O OG1 . THR A 1 250  ? 109.240 117.473 98.132  1.00 62.55  ? 209  THR A OG1 1 
ATOM   1466 C CG2 . THR A 1 250  ? 110.162 116.599 96.088  1.00 62.55  ? 209  THR A CG2 1 
ATOM   1467 N N   . THR A 1 251  ? 108.608 119.619 94.355  1.00 62.76  ? 210  THR A N   1 
ATOM   1468 C CA  . THR A 1 251  ? 108.510 119.884 92.895  1.00 62.76  ? 210  THR A CA  1 
ATOM   1469 C C   . THR A 1 251  ? 109.298 121.150 92.548  1.00 62.76  ? 210  THR A C   1 
ATOM   1470 O O   . THR A 1 251  ? 110.068 121.115 91.567  1.00 62.76  ? 210  THR A O   1 
ATOM   1471 C CB  . THR A 1 251  ? 107.047 120.011 92.457  1.00 62.76  ? 210  THR A CB  1 
ATOM   1472 O OG1 . THR A 1 251  ? 106.366 118.811 92.826  1.00 62.76  ? 210  THR A OG1 1 
ATOM   1473 C CG2 . THR A 1 251  ? 106.895 120.252 90.971  1.00 62.76  ? 210  THR A CG2 1 
ATOM   1474 N N   . THR A 1 252  ? 109.122 122.218 93.331  1.00 63.66  ? 211  THR A N   1 
ATOM   1475 C CA  . THR A 1 252  ? 109.796 123.508 93.023  1.00 63.66  ? 211  THR A CA  1 
ATOM   1476 C C   . THR A 1 252  ? 111.312 123.299 93.028  1.00 63.66  ? 211  THR A C   1 
ATOM   1477 O O   . THR A 1 252  ? 111.970 123.735 92.062  1.00 63.66  ? 211  THR A O   1 
ATOM   1478 C CB  . THR A 1 252  ? 109.377 124.597 94.017  1.00 63.66  ? 211  THR A CB  1 
ATOM   1479 O OG1 . THR A 1 252  ? 107.951 124.635 94.053  1.00 63.66  ? 211  THR A OG1 1 
ATOM   1480 C CG2 . THR A 1 252  ? 109.920 125.963 93.654  1.00 63.66  ? 211  THR A CG2 1 
ATOM   1481 N N   . LEU A 1 253  ? 111.837 122.638 94.065  1.00 65.50  ? 212  LEU A N   1 
ATOM   1482 C CA  . LEU A 1 253  ? 113.308 122.441 94.177  1.00 65.50  ? 212  LEU A CA  1 
ATOM   1483 C C   . LEU A 1 253  ? 113.802 121.613 92.986  1.00 65.50  ? 212  LEU A C   1 
ATOM   1484 O O   . LEU A 1 253  ? 114.840 121.980 92.408  1.00 65.50  ? 212  LEU A O   1 
ATOM   1485 C CB  . LEU A 1 253  ? 113.622 121.745 95.504  1.00 65.50  ? 212  LEU A CB  1 
ATOM   1486 C CG  . LEU A 1 253  ? 113.507 122.633 96.742  1.00 65.50  ? 212  LEU A CG  1 
ATOM   1487 C CD1 . LEU A 1 253  ? 114.359 122.088 97.877  1.00 65.50  ? 212  LEU A CD1 1 
ATOM   1488 C CD2 . LEU A 1 253  ? 113.905 124.063 96.413  1.00 65.50  ? 212  LEU A CD2 1 
ATOM   1489 N N   . SER A 1 254  ? 113.075 120.549 92.633  1.00 70.50  ? 213  SER A N   1 
ATOM   1490 C CA  . SER A 1 254  ? 113.489 119.678 91.503  1.00 70.50  ? 213  SER A CA  1 
ATOM   1491 C C   . SER A 1 254  ? 113.578 120.513 90.222  1.00 70.50  ? 213  SER A C   1 
ATOM   1492 O O   . SER A 1 254  ? 114.591 120.388 89.505  1.00 70.50  ? 213  SER A O   1 
ATOM   1493 C CB  . SER A 1 254  ? 112.538 118.520 91.341  1.00 70.50  ? 213  SER A CB  1 
ATOM   1494 O OG  . SER A 1 254  ? 112.440 117.778 92.548  1.00 70.50  ? 213  SER A OG  1 
ATOM   1495 N N   . LYS A 1 255  ? 112.569 121.349 89.963  1.00 72.98  ? 214  LYS A N   1 
ATOM   1496 C CA  . LYS A 1 255  ? 112.554 122.193 88.739  1.00 72.98  ? 214  LYS A CA  1 
ATOM   1497 C C   . LYS A 1 255  ? 113.766 123.130 88.749  1.00 72.98  ? 214  LYS A C   1 
ATOM   1498 O O   . LYS A 1 255  ? 114.485 123.180 87.728  1.00 72.98  ? 214  LYS A O   1 
ATOM   1499 C CB  . LYS A 1 255  ? 111.238 122.975 88.676  1.00 72.98  ? 214  LYS A CB  1 
ATOM   1500 C CG  . LYS A 1 255  ? 111.270 124.275 87.884  1.00 72.98  ? 214  LYS A CG  1 
ATOM   1501 C CD  . LYS A 1 255  ? 109.904 124.913 87.759  1.00 72.98  ? 214  LYS A CD  1 
ATOM   1502 C CE  . LYS A 1 255  ? 109.952 126.350 87.286  1.00 72.98  ? 214  LYS A CE  1 
ATOM   1503 N NZ  . LYS A 1 255  ? 110.579 127.235 88.297  1.00 72.98  ? 214  LYS A NZ  1 
ATOM   1504 N N   . LEU A 1 256  ? 113.994 123.827 89.865  1.00 70.47  ? 215  LEU A N   1 
ATOM   1505 C CA  . LEU A 1 256  ? 115.125 124.791 89.955  1.00 70.47  ? 215  LEU A CA  1 
ATOM   1506 C C   . LEU A 1 256  ? 116.450 124.025 89.875  1.00 70.47  ? 215  LEU A C   1 
ATOM   1507 O O   . LEU A 1 256  ? 117.403 124.562 89.278  1.00 70.47  ? 215  LEU A O   1 
ATOM   1508 C CB  . LEU A 1 256  ? 115.000 125.576 91.263  1.00 70.47  ? 215  LEU A CB  1 
ATOM   1509 C CG  . LEU A 1 256  ? 113.768 126.477 91.349  1.00 70.47  ? 215  LEU A CG  1 
ATOM   1510 C CD1 . LEU A 1 256  ? 113.849 127.400 92.552  1.00 70.47  ? 215  LEU A CD1 1 
ATOM   1511 C CD2 . LEU A 1 256  ? 113.601 127.283 90.071  1.00 70.47  ? 215  LEU A CD2 1 
ATOM   1512 N N   . SER A 1 257  ? 116.498 122.819 90.449  1.00 73.88  ? 216  SER A N   1 
ATOM   1513 C CA  . SER A 1 257  ? 117.726 121.984 90.383  1.00 73.88  ? 216  SER A CA  1 
ATOM   1514 C C   . SER A 1 257  ? 118.051 121.674 88.918  1.00 73.88  ? 216  SER A C   1 
ATOM   1515 O O   . SER A 1 257  ? 119.238 121.756 88.549  1.00 73.88  ? 216  SER A O   1 
ATOM   1516 C CB  . SER A 1 257  ? 117.565 120.723 91.188  1.00 73.88  ? 216  SER A CB  1 
ATOM   1517 O OG  . SER A 1 257  ? 118.719 119.902 91.078  1.00 73.88  ? 216  SER A OG  1 
ATOM   1518 N N   . ASN A 1 258  ? 117.031 121.345 88.120  1.00 80.94  ? 217  ASN A N   1 
ATOM   1519 C CA  . ASN A 1 258  ? 117.244 121.048 86.679  1.00 80.94  ? 217  ASN A CA  1 
ATOM   1520 C C   . ASN A 1 258  ? 117.857 122.277 86.001  1.00 80.94  ? 217  ASN A C   1 
ATOM   1521 O O   . ASN A 1 258  ? 118.819 122.104 85.225  1.00 80.94  ? 217  ASN A O   1 
ATOM   1522 C CB  . ASN A 1 258  ? 115.948 120.613 85.988  1.00 80.94  ? 217  ASN A CB  1 
ATOM   1523 C CG  . ASN A 1 258  ? 115.403 119.308 86.527  1.00 80.94  ? 217  ASN A CG  1 
ATOM   1524 O OD1 . ASN A 1 258  ? 115.996 118.704 87.418  1.00 80.94  ? 217  ASN A OD1 1 
ATOM   1525 N ND2 . ASN A 1 258  ? 114.277 118.864 85.992  1.00 80.94  ? 217  ASN A ND2 1 
ATOM   1526 N N   . LYS A 1 259  ? 117.328 123.468 86.298  1.00 77.63  ? 218  LYS A N   1 
ATOM   1527 C CA  . LYS A 1 259  ? 117.868 124.718 85.700  1.00 77.63  ? 218  LYS A CA  1 
ATOM   1528 C C   . LYS A 1 259  ? 119.345 124.858 86.083  1.00 77.63  ? 218  LYS A C   1 
ATOM   1529 O O   . LYS A 1 259  ? 120.177 125.072 85.182  1.00 77.63  ? 218  LYS A O   1 
ATOM   1530 C CB  . LYS A 1 259  ? 117.079 125.932 86.194  1.00 77.63  ? 218  LYS A CB  1 
ATOM   1531 C CG  . LYS A 1 259  ? 115.577 125.879 85.951  1.00 77.63  ? 218  LYS A CG  1 
ATOM   1532 C CD  . LYS A 1 259  ? 114.876 127.157 86.349  1.00 77.63  ? 218  LYS A CD  1 
ATOM   1533 C CE  . LYS A 1 259  ? 113.394 127.141 86.047  1.00 77.63  ? 218  LYS A CE  1 
ATOM   1534 N NZ  . LYS A 1 259  ? 112.763 128.448 86.346  1.00 77.63  ? 218  LYS A NZ  1 
ATOM   1535 N N   . SER A 1 260  ? 119.654 124.729 87.375  1.00 81.54  ? 219  SER A N   1 
ATOM   1536 C CA  . SER A 1 260  ? 121.057 124.870 87.839  1.00 81.54  ? 219  SER A CA  1 
ATOM   1537 C C   . SER A 1 260  ? 121.924 123.809 87.154  1.00 81.54  ? 219  SER A C   1 
ATOM   1538 O O   . SER A 1 260  ? 123.050 124.146 86.744  1.00 81.54  ? 219  SER A O   1 
ATOM   1539 C CB  . SER A 1 260  ? 121.143 124.766 89.337  1.00 81.54  ? 219  SER A CB  1 
ATOM   1540 O OG  . SER A 1 260  ? 122.487 124.898 89.774  1.00 81.54  ? 219  SER A OG  1 
ATOM   1541 N N   . GLN A 1 261  ? 121.402 122.587 87.014  1.00 82.47  ? 220  GLN A N   1 
ATOM   1542 C CA  . GLN A 1 261  ? 122.192 121.477 86.417  1.00 82.47  ? 220  GLN A CA  1 
ATOM   1543 C C   . GLN A 1 261  ? 122.625 121.852 84.997  1.00 82.47  ? 220  GLN A C   1 
ATOM   1544 O O   . GLN A 1 261  ? 123.829 121.721 84.698  1.00 82.47  ? 220  GLN A O   1 
ATOM   1545 C CB  . GLN A 1 261  ? 121.365 120.190 86.409  1.00 82.47  ? 220  GLN A CB  1 
ATOM   1546 C CG  . GLN A 1 261  ? 120.717 119.871 87.749  1.00 82.47  ? 220  GLN A CG  1 
ATOM   1547 C CD  . GLN A 1 261  ? 121.728 119.719 88.859  1.00 82.47  ? 220  GLN A CD  1 
ATOM   1548 O OE1 . GLN A 1 261  ? 121.381 119.473 90.012  1.00 82.47  ? 220  GLN A OE1 1 
ATOM   1549 N NE2 . GLN A 1 261  ? 122.997 119.867 88.514  1.00 82.47  ? 220  GLN A NE2 1 
ATOM   1550 N N   . GLU A 1 262  ? 121.689 122.306 84.157  1.00 85.97  ? 221  GLU A N   1 
ATOM   1551 C CA  . GLU A 1 262  ? 122.035 122.603 82.739  1.00 85.97  ? 221  GLU A CA  1 
ATOM   1552 C C   . GLU A 1 262  ? 122.996 123.798 82.690  1.00 85.97  ? 221  GLU A C   1 
ATOM   1553 O O   . GLU A 1 262  ? 123.904 123.785 81.838  1.00 85.97  ? 221  GLU A O   1 
ATOM   1554 C CB  . GLU A 1 262  ? 120.776 122.811 81.890  1.00 85.97  ? 221  GLU A CB  1 
ATOM   1555 C CG  . GLU A 1 262  ? 119.792 123.815 82.459  1.00 85.97  ? 221  GLU A CG  1 
ATOM   1556 C CD  . GLU A 1 262  ? 119.988 125.252 82.007  1.00 85.97  ? 221  GLU A CD  1 
ATOM   1557 O OE1 . GLU A 1 262  ? 120.897 125.498 81.191  1.00 85.97  ? 221  GLU A OE1 1 
ATOM   1558 O OE2 . GLU A 1 262  ? 119.230 126.125 82.475  1.00 85.97  ? 221  GLU A OE2 1 
ATOM   1559 N N   . SER A 1 263  ? 122.808 124.783 83.574  1.00 83.27  ? 222  SER A N   1 
ATOM   1560 C CA  . SER A 1 263  ? 123.727 125.952 83.622  1.00 83.27  ? 222  SER A CA  1 
ATOM   1561 C C   . SER A 1 263  ? 125.142 125.474 83.962  1.00 83.27  ? 222  SER A C   1 
ATOM   1562 O O   . SER A 1 263  ? 126.099 125.957 83.324  1.00 83.27  ? 222  SER A O   1 
ATOM   1563 C CB  . SER A 1 263  ? 123.244 126.983 84.604  1.00 83.27  ? 222  SER A CB  1 
ATOM   1564 O OG  . SER A 1 263  ? 124.094 128.120 84.594  1.00 83.27  ? 222  SER A OG  1 
ATOM   1565 N N   . LEU A 1 264  ? 125.263 124.558 84.927  1.00 86.88  ? 223  LEU A N   1 
ATOM   1566 C CA  . LEU A 1 264  ? 126.592 124.004 85.301  1.00 86.88  ? 223  LEU A CA  1 
ATOM   1567 C C   . LEU A 1 264  ? 127.183 123.268 84.096  1.00 86.88  ? 223  LEU A C   1 
ATOM   1568 O O   . LEU A 1 264  ? 128.406 123.378 83.879  1.00 86.88  ? 223  LEU A O   1 
ATOM   1569 C CB  . LEU A 1 264  ? 126.417 123.057 86.492  1.00 86.88  ? 223  LEU A CB  1 
ATOM   1570 C CG  . LEU A 1 264  ? 126.077 123.732 87.819  1.00 86.88  ? 223  LEU A CG  1 
ATOM   1571 C CD1 . LEU A 1 264  ? 126.125 122.732 88.964  1.00 86.88  ? 223  LEU A CD1 1 
ATOM   1572 C CD2 . LEU A 1 264  ? 127.021 124.894 88.089  1.00 86.88  ? 223  LEU A CD2 1 
ATOM   1573 N N   . SER A 1 265  ? 126.344 122.549 83.344  1.00 87.62  ? 224  SER A N   1 
ATOM   1574 C CA  . SER A 1 265  ? 126.821 121.820 82.141  1.00 87.62  ? 224  SER A CA  1 
ATOM   1575 C C   . SER A 1 265  ? 127.422 122.814 81.141  1.00 87.62  ? 224  SER A C   1 
ATOM   1576 O O   . SER A 1 265  ? 128.472 122.494 80.553  1.00 87.62  ? 224  SER A O   1 
ATOM   1577 C CB  . SER A 1 265  ? 125.706 121.020 81.517  1.00 87.62  ? 224  SER A CB  1 
ATOM   1578 O OG  . SER A 1 265  ? 126.169 120.313 80.376  1.00 87.62  ? 224  SER A OG  1 
ATOM   1579 N N   . GLN A 1 266  ? 126.782 123.975 80.969  1.00 88.55  ? 225  GLN A N   1 
ATOM   1580 C CA  . GLN A 1 266  ? 127.308 125.015 80.047  1.00 88.55  ? 225  GLN A CA  1 
ATOM   1581 C C   . GLN A 1 266  ? 128.712 125.422 80.503  1.00 88.55  ? 225  GLN A C   1 
ATOM   1582 O O   . GLN A 1 266  ? 129.615 125.492 79.646  1.00 88.55  ? 225  GLN A O   1 
ATOM   1583 C CB  . GLN A 1 266  ? 126.383 126.232 80.037  1.00 88.55  ? 225  GLN A CB  1 
ATOM   1584 C CG  . GLN A 1 266  ? 124.945 125.903 79.667  1.00 88.55  ? 225  GLN A CG  1 
ATOM   1585 C CD  . GLN A 1 266  ? 123.990 126.985 80.106  1.00 88.55  ? 225  GLN A CD  1 
ATOM   1586 O OE1 . GLN A 1 266  ? 124.385 127.981 80.709  1.00 88.55  ? 225  GLN A OE1 1 
ATOM   1587 N NE2 . GLN A 1 266  ? 122.716 126.794 79.809  1.00 88.55  ? 225  GLN A NE2 1 
ATOM   1588 N N   . ALA A 1 267  ? 128.884 125.669 81.804  1.00 88.89  ? 226  ALA A N   1 
ATOM   1589 C CA  . ALA A 1 267  ? 130.205 126.069 82.342  1.00 88.89  ? 226  ALA A CA  1 
ATOM   1590 C C   . ALA A 1 267  ? 131.227 124.964 82.056  1.00 88.89  ? 226  ALA A C   1 
ATOM   1591 O O   . ALA A 1 267  ? 132.344 125.290 81.608  1.00 88.89  ? 226  ALA A O   1 
ATOM   1592 C CB  . ALA A 1 267  ? 130.090 126.349 83.820  1.00 88.89  ? 226  ALA A CB  1 
ATOM   1593 N N   . GLY A 1 268  ? 130.849 123.704 82.296  1.00 93.20  ? 227  GLY A N   1 
ATOM   1594 C CA  . GLY A 1 268  ? 131.756 122.572 82.024  1.00 93.20  ? 227  GLY A CA  1 
ATOM   1595 C C   . GLY A 1 268  ? 132.129 122.510 80.554  1.00 93.20  ? 227  GLY A C   1 
ATOM   1596 O O   . GLY A 1 268  ? 133.303 122.217 80.255  1.00 93.20  ? 227  GLY A O   1 
ATOM   1597 N N   . ASN A 1 269  ? 131.167 122.785 79.668  1.00 94.76  ? 228  ASN A N   1 
ATOM   1598 C CA  . ASN A 1 269  ? 131.433 122.773 78.205  1.00 94.76  ? 228  ASN A CA  1 
ATOM   1599 C C   . ASN A 1 269  ? 132.509 123.818 77.890  1.00 94.76  ? 228  ASN A C   1 
ATOM   1600 O O   . ASN A 1 269  ? 133.419 123.508 77.101  1.00 94.76  ? 228  ASN A O   1 
ATOM   1601 C CB  . ASN A 1 269  ? 130.155 123.021 77.400  1.00 94.76  ? 228  ASN A CB  1 
ATOM   1602 C CG  . ASN A 1 269  ? 130.294 122.678 75.932  1.00 94.76  ? 228  ASN A CG  1 
ATOM   1603 O OD1 . ASN A 1 269  ? 131.335 122.194 75.494  1.00 94.76  ? 228  ASN A OD1 1 
ATOM   1604 N ND2 . ASN A 1 269  ? 129.242 122.912 75.164  1.00 94.76  ? 228  ASN A ND2 1 
ATOM   1605 N N   . ILE A 1 270  ? 132.408 125.003 78.500  1.00 90.00  ? 229  ILE A N   1 
ATOM   1606 C CA  . ILE A 1 270  ? 133.416 126.081 78.270  1.00 90.00  ? 229  ILE A CA  1 
ATOM   1607 C C   . ILE A 1 270  ? 134.799 125.537 78.642  1.00 90.00  ? 229  ILE A C   1 
ATOM   1608 O O   . ILE A 1 270  ? 135.734 125.694 77.831  1.00 90.00  ? 229  ILE A O   1 
ATOM   1609 C CB  . ILE A 1 270  ? 133.062 127.341 79.082  1.00 90.00  ? 229  ILE A CB  1 
ATOM   1610 C CG1 . ILE A 1 270  ? 131.664 127.858 78.738  1.00 90.00  ? 229  ILE A CG1 1 
ATOM   1611 C CG2 . ILE A 1 270  ? 134.121 128.417 78.908  1.00 90.00  ? 229  ILE A CG2 1 
ATOM   1612 C CD1 . ILE A 1 270  ? 131.209 129.013 79.595  1.00 90.00  ? 229  ILE A CD1 1 
ATOM   1613 N N   . VAL A 1 271  ? 134.911 124.903 79.812  1.00 93.17  ? 230  VAL A N   1 
ATOM   1614 C CA  . VAL A 1 271  ? 136.220 124.347 80.268  1.00 93.17  ? 230  VAL A CA  1 
ATOM   1615 C C   . VAL A 1 271  ? 136.692 123.300 79.252  1.00 93.17  ? 230  VAL A C   1 
ATOM   1616 O O   . VAL A 1 271  ? 137.869 123.364 78.848  1.00 93.17  ? 230  VAL A O   1 
ATOM   1617 C CB  . VAL A 1 271  ? 136.114 123.749 81.684  1.00 93.17  ? 230  VAL A CB  1 
ATOM   1618 C CG1 . VAL A 1 271  ? 137.378 123.003 82.082  1.00 93.17  ? 230  VAL A CG1 1 
ATOM   1619 C CG2 . VAL A 1 271  ? 135.774 124.810 82.717  1.00 93.17  ? 230  VAL A CG2 1 
ATOM   1620 N N   . GLU A 1 272  ? 135.801 122.391 78.845  1.00 100.84 ? 231  GLU A N   1 
ATOM   1621 C CA  . GLU A 1 272  ? 136.182 121.314 77.892  1.00 100.84 ? 231  GLU A CA  1 
ATOM   1622 C C   . GLU A 1 272  ? 136.703 121.952 76.601  1.00 100.84 ? 231  GLU A C   1 
ATOM   1623 O O   . GLU A 1 272  ? 137.779 121.531 76.130  1.00 100.84 ? 231  GLU A O   1 
ATOM   1624 C CB  . GLU A 1 272  ? 134.981 120.415 77.591  1.00 100.84 ? 231  GLU A CB  1 
ATOM   1625 C CG  . GLU A 1 272  ? 134.349 119.813 78.832  1.00 100.84 ? 231  GLU A CG  1 
ATOM   1626 C CD  . GLU A 1 272  ? 133.095 118.996 78.573  1.00 100.84 ? 231  GLU A CD  1 
ATOM   1627 O OE1 . GLU A 1 272  ? 132.126 119.561 78.030  1.00 100.84 ? 231  GLU A OE1 1 
ATOM   1628 O OE2 . GLU A 1 272  ? 133.090 117.799 78.918  1.00 100.84 ? 231  GLU A OE2 1 
ATOM   1629 N N   . GLN A 1 273  ? 135.954 122.911 76.053  1.00 101.55 ? 232  GLN A N   1 
ATOM   1630 C CA  . GLN A 1 273  ? 136.369 123.600 74.802  1.00 101.55 ? 232  GLN A CA  1 
ATOM   1631 C C   . GLN A 1 273  ? 137.739 124.247 75.018  1.00 101.55 ? 232  GLN A C   1 
ATOM   1632 O O   . GLN A 1 273  ? 138.622 124.070 74.157  1.00 101.55 ? 232  GLN A O   1 
ATOM   1633 C CB  . GLN A 1 273  ? 135.335 124.658 74.421  1.00 101.55 ? 232  GLN A CB  1 
ATOM   1634 C CG  . GLN A 1 273  ? 135.760 125.522 73.244  1.00 101.55 ? 232  GLN A CG  1 
ATOM   1635 C CD  . GLN A 1 273  ? 135.024 126.839 73.218  1.00 101.55 ? 232  GLN A CD  1 
ATOM   1636 O OE1 . GLN A 1 273  ? 135.624 127.909 73.301  1.00 101.55 ? 232  GLN A OE1 1 
ATOM   1637 N NE2 . GLN A 1 273  ? 133.708 126.769 73.104  1.00 101.55 ? 232  GLN A NE2 1 
ATOM   1638 N N   . THR A 1 274  ? 137.908 124.966 76.130  1.00 99.53  ? 233  THR A N   1 
ATOM   1639 C CA  . THR A 1 274  ? 139.187 125.677 76.384  1.00 99.53  ? 233  THR A CA  1 
ATOM   1640 C C   . THR A 1 274  ? 140.331 124.659 76.426  1.00 99.53  ? 233  THR A C   1 
ATOM   1641 O O   . THR A 1 274  ? 141.383 124.939 75.827  1.00 99.53  ? 233  THR A O   1 
ATOM   1642 C CB  . THR A 1 274  ? 139.114 126.497 77.677  1.00 99.53  ? 233  THR A CB  1 
ATOM   1643 O OG1 . THR A 1 274  ? 137.936 127.300 77.624  1.00 99.53  ? 233  THR A OG1 1 
ATOM   1644 C CG2 . THR A 1 274  ? 140.329 127.376 77.883  1.00 99.53  ? 233  THR A CG2 1 
ATOM   1645 N N   . VAL A 1 275  ? 140.124 123.522 77.097  1.00 101.50 ? 234  VAL A N   1 
ATOM   1646 C CA  . VAL A 1 275  ? 141.209 122.506 77.244  1.00 101.50 ? 234  VAL A CA  1 
ATOM   1647 C C   . VAL A 1 275  ? 141.561 121.929 75.867  1.00 101.50 ? 234  VAL A C   1 
ATOM   1648 O O   . VAL A 1 275  ? 142.763 121.781 75.584  1.00 101.50 ? 234  VAL A O   1 
ATOM   1649 C CB  . VAL A 1 275  ? 140.814 121.397 78.239  1.00 101.50 ? 234  VAL A CB  1 
ATOM   1650 C CG1 . VAL A 1 275  ? 141.851 120.287 78.285  1.00 101.50 ? 234  VAL A CG1 1 
ATOM   1651 C CG2 . VAL A 1 275  ? 140.577 121.959 79.632  1.00 101.50 ? 234  VAL A CG2 1 
ATOM   1652 N N   . VAL A 1 276  ? 140.556 121.613 75.045  1.00 103.30 ? 235  VAL A N   1 
ATOM   1653 C CA  . VAL A 1 276  ? 140.839 120.971 73.724  1.00 103.30 ? 235  VAL A CA  1 
ATOM   1654 C C   . VAL A 1 276  ? 141.475 122.007 72.789  1.00 103.30 ? 235  VAL A C   1 
ATOM   1655 O O   . VAL A 1 276  ? 142.199 121.592 71.863  1.00 103.30 ? 235  VAL A O   1 
ATOM   1656 C CB  . VAL A 1 276  ? 139.581 120.327 73.107  1.00 103.30 ? 235  VAL A CB  1 
ATOM   1657 C CG1 . VAL A 1 276  ? 138.961 119.297 74.038  1.00 103.30 ? 235  VAL A CG1 1 
ATOM   1658 C CG2 . VAL A 1 276  ? 138.549 121.359 72.681  1.00 103.30 ? 235  VAL A CG2 1 
ATOM   1659 N N   . GLN A 1 277  ? 141.218 123.297 73.024  1.00 108.14 ? 236  GLN A N   1 
ATOM   1660 C CA  . GLN A 1 277  ? 141.831 124.371 72.198  1.00 108.14 ? 236  GLN A CA  1 
ATOM   1661 C C   . GLN A 1 277  ? 142.949 125.051 72.993  1.00 108.14 ? 236  GLN A C   1 
ATOM   1662 O O   . GLN A 1 277  ? 143.406 126.122 72.555  1.00 108.14 ? 236  GLN A O   1 
ATOM   1663 C CB  . GLN A 1 277  ? 140.788 125.419 71.806  1.00 108.14 ? 236  GLN A CB  1 
ATOM   1664 C CG  . GLN A 1 277  ? 139.632 124.876 70.982  1.00 108.14 ? 236  GLN A CG  1 
ATOM   1665 C CD  . GLN A 1 277  ? 138.692 125.981 70.569  1.00 108.14 ? 236  GLN A CD  1 
ATOM   1666 O OE1 . GLN A 1 277  ? 138.131 126.689 71.402  1.00 108.14 ? 236  GLN A OE1 1 
ATOM   1667 N NE2 . GLN A 1 277  ? 138.524 126.150 69.268  1.00 108.14 ? 236  GLN A NE2 1 
ATOM   1668 N N   . ILE A 1 278  ? 143.395 124.444 74.096  1.00 104.22 ? 237  ILE A N   1 
ATOM   1669 C CA  . ILE A 1 278  ? 144.402 125.117 74.974  1.00 104.22 ? 237  ILE A CA  1 
ATOM   1670 C C   . ILE A 1 278  ? 145.587 125.596 74.124  1.00 104.22 ? 237  ILE A C   1 
ATOM   1671 O O   . ILE A 1 278  ? 146.105 126.690 74.414  1.00 104.22 ? 237  ILE A O   1 
ATOM   1672 C CB  . ILE A 1 278  ? 144.840 124.197 76.133  1.00 104.22 ? 237  ILE A CB  1 
ATOM   1673 C CG1 . ILE A 1 278  ? 145.550 124.984 77.236  1.00 104.22 ? 237  ILE A CG1 1 
ATOM   1674 C CG2 . ILE A 1 278  ? 145.686 123.034 75.634  1.00 104.22 ? 237  ILE A CG2 1 
ATOM   1675 C CD1 . ILE A 1 278  ? 144.783 126.195 77.713  1.00 104.22 ? 237  ILE A CD1 1 
ATOM   1676 N N   . ARG A 1 279  ? 145.985 124.821 73.110  1.00 109.64 ? 238  ARG A N   1 
ATOM   1677 C CA  . ARG A 1 279  ? 147.172 125.194 72.295  1.00 109.64 ? 238  ARG A CA  1 
ATOM   1678 C C   . ARG A 1 279  ? 146.958 126.582 71.686  1.00 109.64 ? 238  ARG A C   1 
ATOM   1679 O O   . ARG A 1 279  ? 147.741 127.491 72.013  1.00 109.64 ? 238  ARG A O   1 
ATOM   1680 C CB  . ARG A 1 279  ? 147.416 124.152 71.199  1.00 109.64 ? 238  ARG A CB  1 
ATOM   1681 C CG  . ARG A 1 279  ? 147.972 122.831 71.710  1.00 109.64 ? 238  ARG A CG  1 
ATOM   1682 C CD  . ARG A 1 279  ? 148.264 121.876 70.569  1.00 109.64 ? 238  ARG A CD  1 
ATOM   1683 N NE  . ARG A 1 279  ? 148.973 120.671 70.976  1.00 109.64 ? 238  ARG A NE  1 
ATOM   1684 C CZ  . ARG A 1 279  ? 150.208 120.643 71.467  1.00 109.64 ? 238  ARG A CZ  1 
ATOM   1685 N NH1 . ARG A 1 279  ? 150.674 119.537 72.017  1.00 109.64 ? 238  ARG A NH1 1 
ATOM   1686 N NH2 . ARG A 1 279  ? 150.976 121.717 71.400  1.00 109.64 ? 238  ARG A NH2 1 
ATOM   1687 N N   . VAL A 1 280  ? 145.922 126.746 70.857  1.00 110.08 ? 239  VAL A N   1 
ATOM   1688 C CA  . VAL A 1 280  ? 145.695 128.051 70.166  1.00 110.08 ? 239  VAL A CA  1 
ATOM   1689 C C   . VAL A 1 280  ? 145.357 129.117 71.218  1.00 110.08 ? 239  VAL A C   1 
ATOM   1690 O O   . VAL A 1 280  ? 145.833 130.261 71.073  1.00 110.08 ? 239  VAL A O   1 
ATOM   1691 C CB  . VAL A 1 280  ? 144.605 127.944 69.080  1.00 110.08 ? 239  VAL A CB  1 
ATOM   1692 C CG1 . VAL A 1 280  ? 143.313 127.345 69.612  1.00 110.08 ? 239  VAL A CG1 1 
ATOM   1693 C CG2 . VAL A 1 280  ? 144.346 129.280 68.400  1.00 110.08 ? 239  VAL A CG2 1 
ATOM   1694 N N   . VAL A 1 281  ? 144.584 128.746 72.243  1.00 104.49 ? 240  VAL A N   1 
ATOM   1695 C CA  . VAL A 1 281  ? 144.185 129.718 73.304  1.00 104.49 ? 240  VAL A CA  1 
ATOM   1696 C C   . VAL A 1 281  ? 145.454 130.272 73.962  1.00 104.49 ? 240  VAL A C   1 
ATOM   1697 O O   . VAL A 1 281  ? 145.552 131.507 74.106  1.00 104.49 ? 240  VAL A O   1 
ATOM   1698 C CB  . VAL A 1 281  ? 143.244 129.065 74.334  1.00 104.49 ? 240  VAL A CB  1 
ATOM   1699 C CG1 . VAL A 1 281  ? 142.984 129.972 75.525  1.00 104.49 ? 240  VAL A CG1 1 
ATOM   1700 C CG2 . VAL A 1 281  ? 141.929 128.633 73.702  1.00 104.49 ? 240  VAL A CG2 1 
ATOM   1701 N N   . MET A 1 282  ? 146.393 129.392 74.326  1.00 107.40 ? 241  MET A N   1 
ATOM   1702 C CA  . MET A 1 282  ? 147.661 129.830 74.971  1.00 107.40 ? 241  MET A CA  1 
ATOM   1703 C C   . MET A 1 282  ? 148.572 130.493 73.931  1.00 107.40 ? 241  MET A C   1 
ATOM   1704 O O   . MET A 1 282  ? 149.261 131.465 74.293  1.00 107.40 ? 241  MET A O   1 
ATOM   1705 C CB  . MET A 1 282  ? 148.395 128.649 75.612  1.00 107.40 ? 241  MET A CB  1 
ATOM   1706 C CG  . MET A 1 282  ? 148.201 128.569 77.113  1.00 107.40 ? 241  MET A CG  1 
ATOM   1707 S SD  . MET A 1 282  ? 148.923 127.066 77.809  1.00 107.40 ? 241  MET A SD  1 
ATOM   1708 C CE  . MET A 1 282  ? 148.812 125.982 76.386  1.00 107.40 ? 241  MET A CE  1 
ATOM   1709 N N   . ALA A 1 283  ? 148.573 129.986 72.695  1.00 109.97 ? 242  ALA A N   1 
ATOM   1710 C CA  . ALA A 1 283  ? 149.412 130.569 71.622  1.00 109.97 ? 242  ALA A CA  1 
ATOM   1711 C C   . ALA A 1 283  ? 149.041 132.045 71.453  1.00 109.97 ? 242  ALA A C   1 
ATOM   1712 O O   . ALA A 1 283  ? 149.954 132.860 71.216  1.00 109.97 ? 242  ALA A O   1 
ATOM   1713 C CB  . ALA A 1 283  ? 149.224 129.801 70.338  1.00 109.97 ? 242  ALA A CB  1 
ATOM   1714 N N   . PHE A 1 284  ? 147.750 132.368 71.566  1.00 110.83 ? 243  PHE A N   1 
ATOM   1715 C CA  . PHE A 1 284  ? 147.310 133.786 71.488  1.00 110.83 ? 243  PHE A CA  1 
ATOM   1716 C C   . PHE A 1 284  ? 147.189 134.336 72.912  1.00 110.83 ? 243  PHE A C   1 
ATOM   1717 O O   . PHE A 1 284  ? 148.115 134.118 73.716  1.00 110.83 ? 243  PHE A O   1 
ATOM   1718 C CB  . PHE A 1 284  ? 145.980 133.893 70.736  1.00 110.83 ? 243  PHE A CB  1 
ATOM   1719 C CG  . PHE A 1 284  ? 146.070 133.649 69.251  1.00 110.83 ? 243  PHE A CG  1 
ATOM   1720 C CD1 . PHE A 1 284  ? 147.292 133.421 68.639  1.00 110.83 ? 243  PHE A CD1 1 
ATOM   1721 C CD2 . PHE A 1 284  ? 144.929 133.641 68.465  1.00 110.83 ? 243  PHE A CD2 1 
ATOM   1722 C CE1 . PHE A 1 284  ? 147.371 133.195 67.273  1.00 110.83 ? 243  PHE A CE1 1 
ATOM   1723 C CE2 . PHE A 1 284  ? 145.010 133.414 67.099  1.00 110.83 ? 243  PHE A CE2 1 
ATOM   1724 C CZ  . PHE A 1 284  ? 146.230 133.192 66.506  1.00 110.83 ? 243  PHE A CZ  1 
ATOM   1725 N N   . VAL A 1 285  ? 146.084 135.023 73.212  1.00 103.10 ? 244  VAL A N   1 
ATOM   1726 C CA  . VAL A 1 285  ? 145.851 135.537 74.596  1.00 103.10 ? 244  VAL A CA  1 
ATOM   1727 C C   . VAL A 1 285  ? 144.385 135.291 74.961  1.00 103.10 ? 244  VAL A C   1 
ATOM   1728 O O   . VAL A 1 285  ? 143.684 136.268 75.294  1.00 103.10 ? 244  VAL A O   1 
ATOM   1729 C CB  . VAL A 1 285  ? 146.229 137.027 74.707  1.00 103.10 ? 244  VAL A CB  1 
ATOM   1730 C CG1 . VAL A 1 285  ? 147.724 137.214 74.916  1.00 103.10 ? 244  VAL A CG1 1 
ATOM   1731 C CG2 . VAL A 1 285  ? 145.752 137.825 73.502  1.00 103.10 ? 244  VAL A CG2 1 
ATOM   1732 N N   . GLY A 1 286  ? 143.943 134.030 74.913  1.00 95.55  ? 245  GLY A N   1 
ATOM   1733 C CA  . GLY A 1 286  ? 142.526 133.718 75.182  1.00 95.55  ? 245  GLY A CA  1 
ATOM   1734 C C   . GLY A 1 286  ? 142.285 133.262 76.609  1.00 95.55  ? 245  GLY A C   1 
ATOM   1735 O O   . GLY A 1 286  ? 141.129 132.931 76.932  1.00 95.55  ? 245  GLY A O   1 
ATOM   1736 N N   . GLU A 1 287  ? 143.333 133.247 77.437  1.00 92.47  ? 246  GLU A N   1 
ATOM   1737 C CA  . GLU A 1 287  ? 143.195 132.776 78.841  1.00 92.47  ? 246  GLU A CA  1 
ATOM   1738 C C   . GLU A 1 287  ? 142.120 133.614 79.538  1.00 92.47  ? 246  GLU A C   1 
ATOM   1739 O O   . GLU A 1 287  ? 141.219 133.018 80.160  1.00 92.47  ? 246  GLU A O   1 
ATOM   1740 C CB  . GLU A 1 287  ? 144.534 132.884 79.575  1.00 92.47  ? 246  GLU A CB  1 
ATOM   1741 C CG  . GLU A 1 287  ? 145.450 131.693 79.353  1.00 92.47  ? 246  GLU A CG  1 
ATOM   1742 C CD  . GLU A 1 287  ? 145.696 131.328 77.900  1.00 92.47  ? 246  GLU A CD  1 
ATOM   1743 O OE1 . GLU A 1 287  ? 145.382 130.183 77.521  1.00 92.47  ? 246  GLU A OE1 1 
ATOM   1744 O OE2 . GLU A 1 287  ? 146.196 132.190 77.149  1.00 92.47  ? 246  GLU A OE2 1 
ATOM   1745 N N   . SER A 1 288  ? 142.208 134.942 79.424  1.00 86.92  ? 247  SER A N   1 
ATOM   1746 C CA  . SER A 1 288  ? 141.187 135.836 80.031  1.00 86.92  ? 247  SER A CA  1 
ATOM   1747 C C   . SER A 1 288  ? 139.848 135.649 79.310  1.00 86.92  ? 247  SER A C   1 
ATOM   1748 O O   . SER A 1 288  ? 138.827 135.475 79.999  1.00 86.92  ? 247  SER A O   1 
ATOM   1749 C CB  . SER A 1 288  ? 141.635 137.271 79.984  1.00 86.92  ? 247  SER A CB  1 
ATOM   1750 O OG  . SER A 1 288  ? 142.876 137.431 80.656  1.00 86.92  ? 247  SER A OG  1 
ATOM   1751 N N   . ARG A 1 289  ? 139.866 135.672 77.975  1.00 87.70  ? 248  ARG A N   1 
ATOM   1752 C CA  . ARG A 1 289  ? 138.617 135.507 77.182  1.00 87.70  ? 248  ARG A CA  1 
ATOM   1753 C C   . ARG A 1 289  ? 137.866 134.273 77.691  1.00 87.70  ? 248  ARG A C   1 
ATOM   1754 O O   . ARG A 1 289  ? 136.646 134.382 77.926  1.00 87.70  ? 248  ARG A O   1 
ATOM   1755 C CB  . ARG A 1 289  ? 138.955 135.379 75.694  1.00 87.70  ? 248  ARG A CB  1 
ATOM   1756 C CG  . ARG A 1 289  ? 139.873 136.475 75.172  1.00 87.70  ? 248  ARG A CG  1 
ATOM   1757 C CD  . ARG A 1 289  ? 140.378 136.197 73.769  1.00 87.70  ? 248  ARG A CD  1 
ATOM   1758 N NE  . ARG A 1 289  ? 139.327 136.253 72.763  1.00 87.70  ? 248  ARG A NE  1 
ATOM   1759 C CZ  . ARG A 1 289  ? 139.345 137.049 71.700  1.00 87.70  ? 248  ARG A CZ  1 
ATOM   1760 N NH1 . ARG A 1 289  ? 138.279 137.142 70.925  1.00 87.70  ? 248  ARG A NH1 1 
ATOM   1761 N NH2 . ARG A 1 289  ? 140.430 137.748 71.414  1.00 87.70  ? 248  ARG A NH2 1 
ATOM   1762 N N   . ALA A 1 290  ? 138.571 133.150 77.856  1.00 80.77  ? 249  ALA A N   1 
ATOM   1763 C CA  . ALA A 1 290  ? 137.929 131.898 78.319  1.00 80.77  ? 249  ALA A CA  1 
ATOM   1764 C C   . ALA A 1 290  ? 137.377 132.097 79.734  1.00 80.77  ? 249  ALA A C   1 
ATOM   1765 O O   . ALA A 1 290  ? 136.240 131.656 79.994  1.00 80.77  ? 249  ALA A O   1 
ATOM   1766 C CB  . ALA A 1 290  ? 138.924 130.766 78.273  1.00 80.77  ? 249  ALA A CB  1 
ATOM   1767 N N   . SER A 1 291  ? 138.155 132.742 80.607  1.00 77.60  ? 250  SER A N   1 
ATOM   1768 C CA  . SER A 1 291  ? 137.711 132.982 82.005  1.00 77.60  ? 250  SER A CA  1 
ATOM   1769 C C   . SER A 1 291  ? 136.435 133.829 82.001  1.00 77.60  ? 250  SER A C   1 
ATOM   1770 O O   . SER A 1 291  ? 135.517 133.510 82.781  1.00 77.60  ? 250  SER A O   1 
ATOM   1771 C CB  . SER A 1 291  ? 138.803 133.637 82.808  1.00 77.60  ? 250  SER A CB  1 
ATOM   1772 O OG  . SER A 1 291  ? 139.989 132.856 82.774  1.00 77.60  ? 250  SER A OG  1 
ATOM   1773 N N   . GLN A 1 292  ? 136.383 134.861 81.154  1.00 77.25  ? 251  GLN A N   1 
ATOM   1774 C CA  . GLN A 1 292  ? 135.185 135.739 81.072  1.00 77.25  ? 251  GLN A CA  1 
ATOM   1775 C C   . GLN A 1 292  ? 133.956 134.885 80.743  1.00 77.25  ? 251  GLN A C   1 
ATOM   1776 O O   . GLN A 1 292  ? 132.940 135.016 81.450  1.00 77.25  ? 251  GLN A O   1 
ATOM   1777 C CB  . GLN A 1 292  ? 135.394 136.817 80.008  1.00 77.25  ? 251  GLN A CB  1 
ATOM   1778 C CG  . GLN A 1 292  ? 136.576 137.730 80.294  1.00 77.25  ? 251  GLN A CG  1 
ATOM   1779 C CD  . GLN A 1 292  ? 137.067 138.429 79.050  1.00 77.25  ? 251  GLN A CD  1 
ATOM   1780 O OE1 . GLN A 1 292  ? 136.525 138.253 77.961  1.00 77.25  ? 251  GLN A OE1 1 
ATOM   1781 N NE2 . GLN A 1 292  ? 138.107 139.231 79.204  1.00 77.25  ? 251  GLN A NE2 1 
ATOM   1782 N N   . ALA A 1 293  ? 134.050 134.053 79.703  1.00 74.31  ? 252  ALA A N   1 
ATOM   1783 C CA  . ALA A 1 293  ? 132.915 133.187 79.305  1.00 74.31  ? 252  ALA A CA  1 
ATOM   1784 C C   . ALA A 1 293  ? 132.520 132.304 80.492  1.00 74.31  ? 252  ALA A C   1 
ATOM   1785 O O   . ALA A 1 293  ? 131.311 132.203 80.783  1.00 74.31  ? 252  ALA A O   1 
ATOM   1786 C CB  . ALA A 1 293  ? 133.298 132.360 78.105  1.00 74.31  ? 252  ALA A CB  1 
ATOM   1787 N N   . TYR A 1 294  ? 133.512 131.707 81.159  1.00 69.91  ? 253  TYR A N   1 
ATOM   1788 C CA  . TYR A 1 294  ? 133.237 130.842 82.335  1.00 69.91  ? 253  TYR A CA  1 
ATOM   1789 C C   . TYR A 1 294  ? 132.537 131.677 83.410  1.00 69.91  ? 253  TYR A C   1 
ATOM   1790 O O   . TYR A 1 294  ? 131.564 131.186 84.008  1.00 69.91  ? 253  TYR A O   1 
ATOM   1791 C CB  . TYR A 1 294  ? 134.543 130.244 82.857  1.00 69.91  ? 253  TYR A CB  1 
ATOM   1792 C CG  . TYR A 1 294  ? 134.384 129.074 83.793  1.00 69.91  ? 253  TYR A CG  1 
ATOM   1793 C CD1 . TYR A 1 294  ? 133.682 127.945 83.409  1.00 69.91  ? 253  TYR A CD1 1 
ATOM   1794 C CD2 . TYR A 1 294  ? 134.959 129.082 85.053  1.00 69.91  ? 253  TYR A CD2 1 
ATOM   1795 C CE1 . TYR A 1 294  ? 133.538 126.862 84.258  1.00 69.91  ? 253  TYR A CE1 1 
ATOM   1796 C CE2 . TYR A 1 294  ? 134.831 128.004 85.913  1.00 69.91  ? 253  TYR A CE2 1 
ATOM   1797 C CZ  . TYR A 1 294  ? 134.115 126.891 85.515  1.00 69.91  ? 253  TYR A CZ  1 
ATOM   1798 O OH  . TYR A 1 294  ? 133.978 125.815 86.356  1.00 69.91  ? 253  TYR A OH  1 
ATOM   1799 N N   . SER A 1 295  ? 133.009 132.909 83.623  1.00 70.46  ? 254  SER A N   1 
ATOM   1800 C CA  . SER A 1 295  ? 132.404 133.802 84.646  1.00 70.46  ? 254  SER A CA  1 
ATOM   1801 C C   . SER A 1 295  ? 130.912 133.979 84.352  1.00 70.46  ? 254  SER A C   1 
ATOM   1802 O O   . SER A 1 295  ? 130.108 133.865 85.296  1.00 70.46  ? 254  SER A O   1 
ATOM   1803 C CB  . SER A 1 295  ? 133.106 135.131 84.674  1.00 70.46  ? 254  SER A CB  1 
ATOM   1804 O OG  . SER A 1 295  ? 134.502 134.959 84.871  1.00 70.46  ? 254  SER A OG  1 
ATOM   1805 N N   . SER A 1 296  ? 130.568 134.236 83.088  1.00 68.33  ? 255  SER A N   1 
ATOM   1806 C CA  . SER A 1 296  ? 129.147 134.450 82.709  1.00 68.33  ? 255  SER A CA  1 
ATOM   1807 C C   . SER A 1 296  ? 128.329 133.206 83.069  1.00 68.33  ? 255  SER A C   1 
ATOM   1808 O O   . SER A 1 296  ? 127.271 133.361 83.709  1.00 68.33  ? 255  SER A O   1 
ATOM   1809 C CB  . SER A 1 296  ? 129.029 134.778 81.246  1.00 68.33  ? 255  SER A CB  1 
ATOM   1810 O OG  . SER A 1 296  ? 129.868 135.873 80.907  1.00 68.33  ? 255  SER A OG  1 
ATOM   1811 N N   . ALA A 1 297  ? 128.815 132.021 82.687  1.00 67.36  ? 256  ALA A N   1 
ATOM   1812 C CA  . ALA A 1 297  ? 128.082 130.765 82.972  1.00 67.36  ? 256  ALA A CA  1 
ATOM   1813 C C   . ALA A 1 297  ? 127.949 130.580 84.487  1.00 67.36  ? 256  ALA A C   1 
ATOM   1814 O O   . ALA A 1 297  ? 126.844 130.226 84.945  1.00 67.36  ? 256  ALA A O   1 
ATOM   1815 C CB  . ALA A 1 297  ? 128.796 129.599 82.335  1.00 67.36  ? 256  ALA A CB  1 
ATOM   1816 N N   . LEU A 1 298  ? 129.033 130.821 85.231  1.00 64.57  ? 257  LEU A N   1 
ATOM   1817 C CA  . LEU A 1 298  ? 129.007 130.661 86.709  1.00 64.57  ? 257  LEU A CA  1 
ATOM   1818 C C   . LEU A 1 298  ? 127.974 131.626 87.298  1.00 64.57  ? 257  LEU A C   1 
ATOM   1819 O O   . LEU A 1 298  ? 127.250 131.222 88.228  1.00 64.57  ? 257  LEU A O   1 
ATOM   1820 C CB  . LEU A 1 298  ? 130.402 130.948 87.271  1.00 64.57  ? 257  LEU A CB  1 
ATOM   1821 C CG  . LEU A 1 298  ? 131.476 129.920 86.922  1.00 64.57  ? 257  LEU A CG  1 
ATOM   1822 C CD1 . LEU A 1 298  ? 132.673 130.062 87.847  1.00 64.57  ? 257  LEU A CD1 1 
ATOM   1823 C CD2 . LEU A 1 298  ? 130.916 128.508 86.986  1.00 64.57  ? 257  LEU A CD2 1 
ATOM   1824 N N   . LYS A 1 299  ? 127.919 132.854 86.774  1.00 64.77  ? 258  LYS A N   1 
ATOM   1825 C CA  . LYS A 1 299  ? 126.956 133.864 87.285  1.00 64.77  ? 258  LYS A CA  1 
ATOM   1826 C C   . LYS A 1 299  ? 125.530 133.344 87.075  1.00 64.77  ? 258  LYS A C   1 
ATOM   1827 O O   . LYS A 1 299  ? 124.732 133.408 88.025  1.00 64.77  ? 258  LYS A O   1 
ATOM   1828 C CB  . LYS A 1 299  ? 127.165 135.208 86.581  1.00 64.77  ? 258  LYS A CB  1 
ATOM   1829 C CG  . LYS A 1 299  ? 126.233 136.324 87.030  1.00 64.77  ? 258  LYS A CG  1 
ATOM   1830 C CD  . LYS A 1 299  ? 126.703 137.696 86.600  1.00 64.77  ? 258  LYS A CD  1 
ATOM   1831 C CE  . LYS A 1 299  ? 128.082 138.031 87.128  1.00 64.77  ? 258  LYS A CE  1 
ATOM   1832 N NZ  . LYS A 1 299  ? 128.139 137.942 88.606  1.00 64.77  ? 258  LYS A NZ  1 
ATOM   1833 N N   . ILE A 1 300  ? 125.237 132.821 85.881  1.00 64.63  ? 259  ILE A N   1 
ATOM   1834 C CA  . ILE A 1 300  ? 123.884 132.258 85.605  1.00 64.63  ? 259  ILE A CA  1 
ATOM   1835 C C   . ILE A 1 300  ? 123.602 131.161 86.634  1.00 64.63  ? 259  ILE A C   1 
ATOM   1836 O O   . ILE A 1 300  ? 122.507 131.178 87.230  1.00 64.63  ? 259  ILE A O   1 
ATOM   1837 C CB  . ILE A 1 300  ? 123.795 131.723 84.163  1.00 64.63  ? 259  ILE A CB  1 
ATOM   1838 C CG1 . ILE A 1 300  ? 124.149 132.801 83.136  1.00 64.63  ? 259  ILE A CG1 1 
ATOM   1839 C CG2 . ILE A 1 300  ? 122.427 131.115 83.894  1.00 64.63  ? 259  ILE A CG2 1 
ATOM   1840 C CD1 . ILE A 1 300  ? 123.294 134.042 83.233  1.00 64.63  ? 259  ILE A CD1 1 
ATOM   1841 N N   . ALA A 1 301  ? 124.568 130.265 86.855  1.00 65.12  ? 260  ALA A N   1 
ATOM   1842 C CA  . ALA A 1 301  ? 124.364 129.136 87.793  1.00 65.12  ? 260  ALA A CA  1 
ATOM   1843 C C   . ALA A 1 301  ? 124.068 129.662 89.202  1.00 65.12  ? 260  ALA A C   1 
ATOM   1844 O O   . ALA A 1 301  ? 123.121 129.150 89.829  1.00 65.12  ? 260  ALA A O   1 
ATOM   1845 C CB  . ALA A 1 301  ? 125.578 128.240 87.783  1.00 65.12  ? 260  ALA A CB  1 
ATOM   1846 N N   . GLN A 1 302  ? 124.842 130.641 89.679  1.00 62.57  ? 261  GLN A N   1 
ATOM   1847 C CA  . GLN A 1 302  ? 124.656 131.124 91.076  1.00 62.57  ? 261  GLN A CA  1 
ATOM   1848 C C   . GLN A 1 302  ? 123.279 131.788 91.200  1.00 62.57  ? 261  GLN A C   1 
ATOM   1849 O O   . GLN A 1 302  ? 122.629 131.590 92.242  1.00 62.57  ? 261  GLN A O   1 
ATOM   1850 C CB  . GLN A 1 302  ? 125.798 132.051 91.508  1.00 62.57  ? 261  GLN A CB  1 
ATOM   1851 C CG  . GLN A 1 302  ? 125.752 133.440 90.892  1.00 62.57  ? 261  GLN A CG  1 
ATOM   1852 C CD  . GLN A 1 302  ? 126.751 134.376 91.526  1.00 62.57  ? 261  GLN A CD  1 
ATOM   1853 O OE1 . GLN A 1 302  ? 127.458 134.015 92.464  1.00 62.57  ? 261  GLN A OE1 1 
ATOM   1854 N NE2 . GLN A 1 302  ? 126.810 135.596 91.018  1.00 62.57  ? 261  GLN A NE2 1 
ATOM   1855 N N   . LYS A 1 303  ? 122.849 132.527 90.172  1.00 63.01  ? 262  LYS A N   1 
ATOM   1856 C CA  . LYS A 1 303  ? 121.504 133.160 90.198  1.00 63.01  ? 262  LYS A CA  1 
ATOM   1857 C C   . LYS A 1 303  ? 120.448 132.062 90.350  1.00 63.01  ? 262  LYS A C   1 
ATOM   1858 O O   . LYS A 1 303  ? 119.548 132.222 91.195  1.00 63.01  ? 262  LYS A O   1 
ATOM   1859 C CB  . LYS A 1 303  ? 121.267 133.990 88.933  1.00 63.01  ? 262  LYS A CB  1 
ATOM   1860 C CG  . LYS A 1 303  ? 122.264 135.118 88.705  1.00 63.01  ? 262  LYS A CG  1 
ATOM   1861 C CD  . LYS A 1 303  ? 122.568 135.905 89.960  1.00 63.01  ? 262  LYS A CD  1 
ATOM   1862 C CE  . LYS A 1 303  ? 123.707 136.886 89.783  1.00 63.01  ? 262  LYS A CE  1 
ATOM   1863 N NZ  . LYS A 1 303  ? 124.040 137.577 91.050  1.00 63.01  ? 262  LYS A NZ  1 
ATOM   1864 N N   . LEU A 1 304  ? 120.563 130.989 89.563  1.00 65.11  ? 263  LEU A N   1 
ATOM   1865 C CA  . LEU A 1 304  ? 119.612 129.851 89.675  1.00 65.11  ? 263  LEU A CA  1 
ATOM   1866 C C   . LEU A 1 304  ? 119.717 129.262 91.085  1.00 65.11  ? 263  LEU A C   1 
ATOM   1867 O O   . LEU A 1 304  ? 118.667 128.916 91.655  1.00 65.11  ? 263  LEU A O   1 
ATOM   1868 C CB  . LEU A 1 304  ? 119.959 128.810 88.607  1.00 65.11  ? 263  LEU A CB  1 
ATOM   1869 C CG  . LEU A 1 304  ? 119.840 129.303 87.166  1.00 65.11  ? 263  LEU A CG  1 
ATOM   1870 C CD1 . LEU A 1 304  ? 120.162 128.191 86.181  1.00 65.11  ? 263  LEU A CD1 1 
ATOM   1871 C CD2 . LEU A 1 304  ? 118.453 129.863 86.900  1.00 65.11  ? 263  LEU A CD2 1 
ATOM   1872 N N   . GLY A 1 305  ? 120.938 129.161 91.619  1.00 62.44  ? 264  GLY A N   1 
ATOM   1873 C CA  . GLY A 1 305  ? 121.127 128.660 92.994  1.00 62.44  ? 264  GLY A CA  1 
ATOM   1874 C C   . GLY A 1 305  ? 120.443 129.567 94.003  1.00 62.44  ? 264  GLY A C   1 
ATOM   1875 O O   . GLY A 1 305  ? 119.813 129.037 94.936  1.00 62.44  ? 264  GLY A O   1 
ATOM   1876 N N   . TYR A 1 306  ? 120.547 130.885 93.813  1.00 59.76  ? 265  TYR A N   1 
ATOM   1877 C CA  . TYR A 1 306  ? 119.865 131.847 94.716  1.00 59.76  ? 265  TYR A CA  1 
ATOM   1878 C C   . TYR A 1 306  ? 118.371 131.521 94.738  1.00 59.76  ? 265  TYR A C   1 
ATOM   1879 O O   . TYR A 1 306  ? 117.794 131.420 95.838  1.00 59.76  ? 265  TYR A O   1 
ATOM   1880 C CB  . TYR A 1 306  ? 120.080 133.282 94.233  1.00 59.76  ? 265  TYR A CB  1 
ATOM   1881 C CG  . TYR A 1 306  ? 121.499 133.786 94.304  1.00 59.76  ? 265  TYR A CG  1 
ATOM   1882 C CD1 . TYR A 1 306  ? 122.479 133.094 94.995  1.00 59.76  ? 265  TYR A CD1 1 
ATOM   1883 C CD2 . TYR A 1 306  ? 121.868 134.950 93.650  1.00 59.76  ? 265  TYR A CD2 1 
ATOM   1884 C CE1 . TYR A 1 306  ? 123.784 133.554 95.052  1.00 59.76  ? 265  TYR A CE1 1 
ATOM   1885 C CE2 . TYR A 1 306  ? 123.168 135.423 93.694  1.00 59.76  ? 265  TYR A CE2 1 
ATOM   1886 C CZ  . TYR A 1 306  ? 124.130 134.723 94.398  1.00 59.76  ? 265  TYR A CZ  1 
ATOM   1887 O OH  . TYR A 1 306  ? 125.418 135.195 94.440  1.00 59.76  ? 265  TYR A OH  1 
ATOM   1888 N N   . LYS A 1 307  ? 117.771 131.351 93.556  1.00 58.94  ? 266  LYS A N   1 
ATOM   1889 C CA  . LYS A 1 307  ? 116.332 130.990 93.476  1.00 58.94  ? 266  LYS A CA  1 
ATOM   1890 C C   . LYS A 1 307  ? 116.124 129.656 94.195  1.00 58.94  ? 266  LYS A C   1 
ATOM   1891 O O   . LYS A 1 307  ? 115.198 129.570 95.023  1.00 58.94  ? 266  LYS A O   1 
ATOM   1892 C CB  . LYS A 1 307  ? 115.899 130.856 92.014  1.00 58.94  ? 266  LYS A CB  1 
ATOM   1893 C CG  . LYS A 1 307  ? 116.208 132.050 91.123  1.00 58.94  ? 266  LYS A CG  1 
ATOM   1894 C CD  . LYS A 1 307  ? 116.178 131.699 89.651  1.00 58.94  ? 266  LYS A CD  1 
ATOM   1895 C CE  . LYS A 1 307  ? 114.943 130.917 89.260  1.00 58.94  ? 266  LYS A CE  1 
ATOM   1896 N NZ  . LYS A 1 307  ? 114.990 130.485 87.843  1.00 58.94  ? 266  LYS A NZ  1 
ATOM   1897 N N   . THR A 1 308  ? 116.964 128.664 93.887  1.00 58.27  ? 267  THR A N   1 
ATOM   1898 C CA  . THR A 1 308  ? 116.851 127.332 94.533  1.00 58.27  ? 267  THR A CA  1 
ATOM   1899 C C   . THR A 1 308  ? 116.843 127.516 96.054  1.00 58.27  ? 267  THR A C   1 
ATOM   1900 O O   . THR A 1 308  ? 115.957 126.933 96.710  1.00 58.27  ? 267  THR A O   1 
ATOM   1901 C CB  . THR A 1 308  ? 117.986 126.402 94.087  1.00 58.27  ? 267  THR A CB  1 
ATOM   1902 O OG1 . THR A 1 308  ? 118.076 126.455 92.663  1.00 58.27  ? 267  THR A OG1 1 
ATOM   1903 C CG2 . THR A 1 308  ? 117.785 124.971 94.537  1.00 58.27  ? 267  THR A CG2 1 
ATOM   1904 N N   . GLY A 1 309  ? 117.786 128.300 96.586  1.00 54.53  ? 268  GLY A N   1 
ATOM   1905 C CA  . GLY A 1 309  ? 117.858 128.468 98.029  1.00 54.53  ? 268  GLY A CA  1 
ATOM   1906 C C   . GLY A 1 309  ? 116.651 129.192 98.589  1.00 54.53  ? 268  GLY A C   1 
ATOM   1907 O O   . GLY A 1 309  ? 116.104 128.803 99.627  1.00 54.53  ? 268  GLY A O   1 
ATOM   1908 N N   . LEU A 1 310  ? 116.213 130.252 97.906  1.00 52.38  ? 269  LEU A N   1 
ATOM   1909 C CA  . LEU A 1 310  ? 115.023 130.970 98.351  1.00 52.38  ? 269  LEU A CA  1 
ATOM   1910 C C   . LEU A 1 310  ? 113.798 130.066 98.340  1.00 52.38  ? 269  LEU A C   1 
ATOM   1911 O O   . LEU A 1 310  ? 112.987 130.094 99.273  1.00 52.38  ? 269  LEU A O   1 
ATOM   1912 C CB  . LEU A 1 310  ? 114.795 132.194 97.469  1.00 52.38  ? 269  LEU A CB  1 
ATOM   1913 C CG  . LEU A 1 310  ? 113.500 132.969 97.692  1.00 52.38  ? 269  LEU A CG  1 
ATOM   1914 C CD1 . LEU A 1 310  ? 113.431 133.489 99.115  1.00 52.38  ? 269  LEU A CD1 1 
ATOM   1915 C CD2 . LEU A 1 310  ? 113.393 134.110 96.698  1.00 52.38  ? 269  LEU A CD2 1 
ATOM   1916 N N   . ALA A 1 311  ? 113.646 129.255 97.291  1.00 52.16  ? 270  ALA A N   1 
ATOM   1917 C CA  . ALA A 1 311  ? 112.502 128.352 97.213  1.00 52.16  ? 270  ALA A CA  1 
ATOM   1918 C C   . ALA A 1 311  ? 112.538 127.307 98.321  1.00 52.16  ? 270  ALA A C   1 
ATOM   1919 O O   . ALA A 1 311  ? 111.502 126.987 98.914  1.00 52.16  ? 270  ALA A O   1 
ATOM   1920 C CB  . ALA A 1 311  ? 112.458 127.680 95.843  1.00 52.16  ? 270  ALA A CB  1 
ATOM   1921 N N   . LYS A 1 312  ? 113.719 126.754 98.607  1.00 54.83  ? 271  LYS A N   1 
ATOM   1922 C CA  . LYS A 1 312  ? 113.829 125.774 99.684  1.00 54.83  ? 271  LYS A CA  1 
ATOM   1923 C C   . LYS A 1 312  ? 113.469 126.393 101.029 1.00 54.83  ? 271  LYS A C   1 
ATOM   1924 O O   . LYS A 1 312  ? 112.737 125.789 101.831 1.00 54.83  ? 271  LYS A O   1 
ATOM   1925 C CB  . LYS A 1 312  ? 115.244 125.201 99.719  1.00 54.83  ? 271  LYS A CB  1 
ATOM   1926 C CG  . LYS A 1 312  ? 115.612 124.505 101.013 1.00 54.83  ? 271  LYS A CG  1 
ATOM   1927 C CD  . LYS A 1 312  ? 117.000 123.898 100.919 1.00 54.83  ? 271  LYS A CD  1 
ATOM   1928 C CE  . LYS A 1 312  ? 117.380 123.178 102.199 1.00 54.83  ? 271  LYS A CE  1 
ATOM   1929 N NZ  . LYS A 1 312  ? 118.840 123.270 102.478 1.00 54.83  ? 271  LYS A NZ  1 
ATOM   1930 N N   . GLY A 1 313  ? 113.968 127.603 101.289 1.00 53.24  ? 272  GLY A N   1 
ATOM   1931 C CA  . GLY A 1 313  ? 113.620 128.282 102.524 1.00 53.24  ? 272  GLY A CA  1 
ATOM   1932 C C   . GLY A 1 313  ? 112.133 128.542 102.641 1.00 53.24  ? 272  GLY A C   1 
ATOM   1933 O O   . GLY A 1 313  ? 111.538 128.327 103.699 1.00 53.24  ? 272  GLY A O   1 
ATOM   1934 N N   . MET A 1 314  ? 111.509 128.997 101.552 1.00 54.81  ? 273  MET A N   1 
ATOM   1935 C CA  . MET A 1 314  ? 110.075 129.256 101.587 1.00 54.81  ? 273  MET A CA  1 
ATOM   1936 C C   . MET A 1 314  ? 109.290 127.976 101.823 1.00 54.81  ? 273  MET A C   1 
ATOM   1937 O O   . MET A 1 314  ? 108.301 127.979 102.559 1.00 54.81  ? 273  MET A O   1 
ATOM   1938 C CB  . MET A 1 314  ? 109.621 129.930 100.293 1.00 54.81  ? 273  MET A CB  1 
ATOM   1939 C CG  . MET A 1 314  ? 109.570 131.442 100.377 1.00 54.81  ? 273  MET A CG  1 
ATOM   1940 S SD  . MET A 1 314  ? 108.586 132.180 99.062  1.00 54.81  ? 273  MET A SD  1 
ATOM   1941 C CE  . MET A 1 314  ? 109.511 131.670 97.618  1.00 54.81  ? 273  MET A CE  1 
ATOM   1942 N N   . GLY A 1 315  ? 109.717 126.869 101.216 1.00 54.52  ? 274  GLY A N   1 
ATOM   1943 C CA  . GLY A 1 315  ? 109.008 125.616 101.422 1.00 54.52  ? 274  GLY A CA  1 
ATOM   1944 C C   . GLY A 1 315  ? 109.071 125.141 102.861 1.00 54.52  ? 274  GLY A C   1 
ATOM   1945 O O   . GLY A 1 315  ? 108.053 124.756 103.450 1.00 54.52  ? 274  GLY A O   1 
ATOM   1946 N N   . LEU A 1 316  ? 110.268 125.168 103.452 1.00 54.11  ? 275  LEU A N   1 
ATOM   1947 C CA  . LEU A 1 316  ? 110.392 124.744 104.845 1.00 54.11  ? 275  LEU A CA  1 
ATOM   1948 C C   . LEU A 1 316  ? 109.627 125.675 105.778 1.00 54.11  ? 275  LEU A C   1 
ATOM   1949 O O   . LEU A 1 316  ? 108.962 125.220 106.719 1.00 54.11  ? 275  LEU A O   1 
ATOM   1950 C CB  . LEU A 1 316  ? 111.862 124.664 105.247 1.00 54.11  ? 275  LEU A CB  1 
ATOM   1951 C CG  . LEU A 1 316  ? 112.609 123.470 104.658 1.00 54.11  ? 275  LEU A CG  1 
ATOM   1952 C CD1 . LEU A 1 316  ? 113.921 123.258 105.377 1.00 54.11  ? 275  LEU A CD1 1 
ATOM   1953 C CD2 . LEU A 1 316  ? 111.752 122.221 104.732 1.00 54.11  ? 275  LEU A CD2 1 
ATOM   1954 N N   . GLY A 1 317  ? 109.697 126.982 105.531 1.00 52.93  ? 276  GLY A N   1 
ATOM   1955 C CA  . GLY A 1 317  ? 108.936 127.908 106.347 1.00 52.93  ? 276  GLY A CA  1 
ATOM   1956 C C   . GLY A 1 317  ? 107.442 127.681 106.243 1.00 52.93  ? 276  GLY A C   1 
ATOM   1957 O O   . GLY A 1 317  ? 106.727 127.743 107.244 1.00 52.93  ? 276  GLY A O   1 
ATOM   1958 N N   . ALA A 1 318  ? 106.949 127.419 105.032 1.00 52.85  ? 277  ALA A N   1 
ATOM   1959 C CA  . ALA A 1 318  ? 105.520 127.204 104.844 1.00 52.85  ? 277  ALA A CA  1 
ATOM   1960 C C   . ALA A 1 318  ? 105.058 125.943 105.557 1.00 52.85  ? 277  ALA A C   1 
ATOM   1961 O O   . ALA A 1 318  ? 103.999 125.933 106.199 1.00 52.85  ? 277  ALA A O   1 
ATOM   1962 C CB  . ALA A 1 318  ? 105.192 127.131 103.355 1.00 52.85  ? 277  ALA A CB  1 
ATOM   1963 N N   . THR A 1 319  ? 105.833 124.861 105.454 1.00 50.74  ? 278  THR A N   1 
ATOM   1964 C CA  . THR A 1 319  ? 105.405 123.638 106.125 1.00 50.74  ? 278  THR A CA  1 
ATOM   1965 C C   . THR A 1 319  ? 105.440 123.805 107.641 1.00 50.74  ? 278  THR A C   1 
ATOM   1966 O O   . THR A 1 319  ? 104.544 123.320 108.339 1.00 50.74  ? 278  THR A O   1 
ATOM   1967 C CB  . THR A 1 319  ? 106.238 122.432 105.674 1.00 50.74  ? 278  THR A CB  1 
ATOM   1968 O OG1 . THR A 1 319  ? 105.749 121.251 106.319 1.00 50.74  ? 278  THR A OG1 1 
ATOM   1969 C CG2 . THR A 1 319  ? 107.693 122.593 106.012 1.00 50.74  ? 278  THR A CG2 1 
ATOM   1970 N N   . TYR A 1 320  ? 106.437 124.524 108.170 1.00 50.73  ? 279  TYR A N   1 
ATOM   1971 C CA  . TYR A 1 320  ? 106.458 124.774 109.610 1.00 50.73  ? 279  TYR A CA  1 
ATOM   1972 C C   . TYR A 1 320  ? 105.285 125.644 110.045 1.00 50.73  ? 279  TYR A C   1 
ATOM   1973 O O   . TYR A 1 320  ? 104.681 125.400 111.095 1.00 50.73  ? 279  TYR A O   1 
ATOM   1974 C CB  . TYR A 1 320  ? 107.781 125.415 110.016 1.00 50.73  ? 279  TYR A CB  1 
ATOM   1975 C CG  . TYR A 1 320  ? 108.862 124.411 110.319 1.00 50.73  ? 279  TYR A CG  1 
ATOM   1976 C CD1 . TYR A 1 320  ? 108.672 123.064 110.060 1.00 50.73  ? 279  TYR A CD1 1 
ATOM   1977 C CD2 . TYR A 1 320  ? 110.074 124.809 110.860 1.00 50.73  ? 279  TYR A CD2 1 
ATOM   1978 C CE1 . TYR A 1 320  ? 109.657 122.140 110.331 1.00 50.73  ? 279  TYR A CE1 1 
ATOM   1979 C CE2 . TYR A 1 320  ? 111.066 123.894 111.134 1.00 50.73  ? 279  TYR A CE2 1 
ATOM   1980 C CZ  . TYR A 1 320  ? 110.853 122.560 110.867 1.00 50.73  ? 279  TYR A CZ  1 
ATOM   1981 O OH  . TYR A 1 320  ? 111.839 121.640 111.141 1.00 50.73  ? 279  TYR A OH  1 
ATOM   1982 N N   . PHE A 1 321  ? 104.952 126.666 109.258 1.00 48.36  ? 280  PHE A N   1 
ATOM   1983 C CA  . PHE A 1 321  ? 103.814 127.522 109.577 1.00 48.36  ? 280  PHE A CA  1 
ATOM   1984 C C   . PHE A 1 321  ? 102.523 126.716 109.630 1.00 48.36  ? 280  PHE A C   1 
ATOM   1985 O O   . PHE A 1 321  ? 101.733 126.835 110.579 1.00 48.36  ? 280  PHE A O   1 
ATOM   1986 C CB  . PHE A 1 321  ? 103.721 128.636 108.534 1.00 48.36  ? 280  PHE A CB  1 
ATOM   1987 C CG  . PHE A 1 321  ? 102.482 129.477 108.634 1.00 48.36  ? 280  PHE A CG  1 
ATOM   1988 C CD1 . PHE A 1 321  ? 102.396 130.502 109.554 1.00 48.36  ? 280  PHE A CD1 1 
ATOM   1989 C CD2 . PHE A 1 321  ? 101.406 129.251 107.792 1.00 48.36  ? 280  PHE A CD2 1 
ATOM   1990 C CE1 . PHE A 1 321  ? 101.261 131.280 109.639 1.00 48.36  ? 280  PHE A CE1 1 
ATOM   1991 C CE2 . PHE A 1 321  ? 100.268 130.024 107.875 1.00 48.36  ? 280  PHE A CE2 1 
ATOM   1992 C CZ  . PHE A 1 321  ? 100.196 131.039 108.797 1.00 48.36  ? 280  PHE A CZ  1 
ATOM   1993 N N   . VAL A 1 322  ? 102.302 125.875 108.619 1.00 47.23  ? 281  VAL A N   1 
ATOM   1994 C CA  . VAL A 1 322  ? 101.087 125.068 108.576 1.00 47.23  ? 281  VAL A CA  1 
ATOM   1995 C C   . VAL A 1 322  ? 101.052 124.100 109.751 1.00 47.23  ? 281  VAL A C   1 
ATOM   1996 O O   . VAL A 1 322  ? 100.015 123.924 110.398 1.00 47.23  ? 281  VAL A O   1 
ATOM   1997 C CB  . VAL A 1 322  ? 100.978 124.330 107.232 1.00 47.23  ? 281  VAL A CB  1 
ATOM   1998 C CG1 . VAL A 1 322  ? 99.865  123.303 107.283 1.00 47.23  ? 281  VAL A CG1 1 
ATOM   1999 C CG2 . VAL A 1 322  ? 100.734 125.320 106.113 1.00 47.23  ? 281  VAL A CG2 1 
ATOM   2000 N N   . VAL A 1 323  ? 102.188 123.466 110.051 1.00 49.21  ? 282  VAL A N   1 
ATOM   2001 C CA  . VAL A 1 323  ? 102.238 122.516 111.159 1.00 49.21  ? 282  VAL A CA  1 
ATOM   2002 C C   . VAL A 1 323  ? 101.894 123.207 112.472 1.00 49.21  ? 282  VAL A C   1 
ATOM   2003 O O   . VAL A 1 323  ? 101.104 122.694 113.273 1.00 49.21  ? 282  VAL A O   1 
ATOM   2004 C CB  . VAL A 1 323  ? 103.619 121.841 111.221 1.00 49.21  ? 282  VAL A CB  1 
ATOM   2005 C CG1 . VAL A 1 323  ? 103.835 121.193 112.568 1.00 49.21  ? 282  VAL A CG1 1 
ATOM   2006 C CG2 . VAL A 1 323  ? 103.739 120.803 110.126 1.00 49.21  ? 282  VAL A CG2 1 
ATOM   2007 N N   . PHE A 1 324  ? 102.473 124.384 112.712 1.00 69.10  ? 283  PHE A N   1 
ATOM   2008 C CA  . PHE A 1 324  ? 102.222 125.077 113.969 1.00 69.10  ? 283  PHE A CA  1 
ATOM   2009 C C   . PHE A 1 324  ? 100.758 125.477 114.099 1.00 69.10  ? 283  PHE A C   1 
ATOM   2010 O O   . PHE A 1 324  ? 100.137 125.260 115.145 1.00 69.10  ? 283  PHE A O   1 
ATOM   2011 C CB  . PHE A 1 324  ? 103.123 126.302 114.101 1.00 69.10  ? 283  PHE A CB  1 
ATOM   2012 C CG  . PHE A 1 324  ? 104.537 125.984 114.482 1.00 69.10  ? 283  PHE A CG  1 
ATOM   2013 C CD1 . PHE A 1 324  ? 105.019 124.691 114.411 1.00 69.10  ? 283  PHE A CD1 1 
ATOM   2014 C CD2 . PHE A 1 324  ? 105.377 126.977 114.945 1.00 69.10  ? 283  PHE A CD2 1 
ATOM   2015 C CE1 . PHE A 1 324  ? 106.319 124.404 114.768 1.00 69.10  ? 283  PHE A CE1 1 
ATOM   2016 C CE2 . PHE A 1 324  ? 106.675 126.692 115.309 1.00 69.10  ? 283  PHE A CE2 1 
ATOM   2017 C CZ  . PHE A 1 324  ? 107.146 125.404 115.219 1.00 69.10  ? 283  PHE A CZ  1 
ATOM   2018 N N   . CYS A 1 325  ? 100.178 126.047 113.041 1.00 56.09  ? 284  CYS A N   1 
ATOM   2019 C CA  . CYS A 1 325  ? 98.776  126.455 113.127 1.00 56.09  ? 284  CYS A CA  1 
ATOM   2020 C C   . CYS A 1 325  ? 97.862  125.248 113.322 1.00 56.09  ? 284  CYS A C   1 
ATOM   2021 O O   . CYS A 1 325  ? 96.914  125.283 114.122 1.00 56.09  ? 284  CYS A O   1 
ATOM   2022 C CB  . CYS A 1 325  ? 98.380  127.240 111.879 1.00 56.09  ? 284  CYS A CB  1 
ATOM   2023 S SG  . CYS A 1 325  ? 99.323  128.757 111.633 1.00 56.09  ? 284  CYS A SG  1 
ATOM   2024 N N   . CYS A 1 326  ? 98.146  124.159 112.609 1.00 68.26  ? 285  CYS A N   1 
ATOM   2025 C CA  . CYS A 1 326  ? 97.282  122.989 112.673 1.00 68.26  ? 285  CYS A CA  1 
ATOM   2026 C C   . CYS A 1 326  ? 97.355  122.313 114.035 1.00 68.26  ? 285  CYS A C   1 
ATOM   2027 O O   . CYS A 1 326  ? 96.331  121.893 114.579 1.00 68.26  ? 285  CYS A O   1 
ATOM   2028 C CB  . CYS A 1 326  ? 97.650  122.022 111.554 1.00 68.26  ? 285  CYS A CB  1 
ATOM   2029 S SG  . CYS A 1 326  ? 97.282  122.670 109.906 1.00 68.26  ? 285  CYS A SG  1 
ATOM   2030 N N   . TYR A 1 327  ? 98.554  122.194 114.609 1.00 50.84  ? 286  TYR A N   1 
ATOM   2031 C CA  . TYR A 1 327  ? 98.638  121.662 115.967 1.00 50.84  ? 286  TYR A CA  1 
ATOM   2032 C C   . TYR A 1 327  ? 98.070  122.621 117.000 1.00 50.84  ? 286  TYR A C   1 
ATOM   2033 O O   . TYR A 1 327  ? 97.583  122.180 118.040 1.00 50.84  ? 286  TYR A O   1 
ATOM   2034 C CB  . TYR A 1 327  ? 100.064 121.256 116.326 1.00 50.84  ? 286  TYR A CB  1 
ATOM   2035 C CG  . TYR A 1 327  ? 100.486 119.948 115.710 1.00 50.84  ? 286  TYR A CG  1 
ATOM   2036 C CD1 . TYR A 1 327  ? 100.115 118.750 116.302 1.00 50.84  ? 286  TYR A CD1 1 
ATOM   2037 C CD2 . TYR A 1 327  ? 101.233 119.897 114.549 1.00 50.84  ? 286  TYR A CD2 1 
ATOM   2038 C CE1 . TYR A 1 327  ? 100.481 117.545 115.768 1.00 50.84  ? 286  TYR A CE1 1 
ATOM   2039 C CE2 . TYR A 1 327  ? 101.605 118.686 114.002 1.00 50.84  ? 286  TYR A CE2 1 
ATOM   2040 C CZ  . TYR A 1 327  ? 101.225 117.515 114.618 1.00 50.84  ? 286  TYR A CZ  1 
ATOM   2041 O OH  . TYR A 1 327  ? 101.589 116.305 114.084 1.00 50.84  ? 286  TYR A OH  1 
ATOM   2042 N N   . ALA A 1 328  ? 98.089  123.927 116.739 1.00 53.28  ? 287  ALA A N   1 
ATOM   2043 C CA  . ALA A 1 328  ? 97.361  124.828 117.627 1.00 53.28  ? 287  ALA A CA  1 
ATOM   2044 C C   . ALA A 1 328  ? 95.886  124.456 117.665 1.00 53.28  ? 287  ALA A C   1 
ATOM   2045 O O   . ALA A 1 328  ? 95.302  124.257 118.742 1.00 53.28  ? 287  ALA A O   1 
ATOM   2046 C CB  . ALA A 1 328  ? 97.543  126.276 117.179 1.00 53.28  ? 287  ALA A CB  1 
ATOM   2047 N N   . LEU A 1 329  ? 95.279  124.313 116.486 1.00 48.91  ? 288  LEU A N   1 
ATOM   2048 C CA  . LEU A 1 329  ? 93.868  123.934 116.424 1.00 48.91  ? 288  LEU A CA  1 
ATOM   2049 C C   . LEU A 1 329  ? 93.629  122.572 117.068 1.00 48.91  ? 288  LEU A C   1 
ATOM   2050 O O   . LEU A 1 329  ? 92.673  122.389 117.834 1.00 48.91  ? 288  LEU A O   1 
ATOM   2051 C CB  . LEU A 1 329  ? 93.391  123.928 114.974 1.00 48.91  ? 288  LEU A CB  1 
ATOM   2052 C CG  . LEU A 1 329  ? 92.024  123.281 114.755 1.00 48.91  ? 288  LEU A CG  1 
ATOM   2053 C CD1 . LEU A 1 329  ? 90.931  124.078 115.446 1.00 48.91  ? 288  LEU A CD1 1 
ATOM   2054 C CD2 . LEU A 1 329  ? 91.728  123.131 113.274 1.00 48.91  ? 288  LEU A CD2 1 
ATOM   2055 N N   . LEU A 1 330  ? 94.494  121.600 116.769 1.00 41.64  ? 289  LEU A N   1 
ATOM   2056 C CA  . LEU A 1 330  ? 94.299  120.243 117.271 1.00 41.64  ? 289  LEU A CA  1 
ATOM   2057 C C   . LEU A 1 330  ? 94.435  120.181 118.785 1.00 41.64  ? 289  LEU A C   1 
ATOM   2058 O O   . LEU A 1 330  ? 93.669  119.481 119.451 1.00 41.64  ? 289  LEU A O   1 
ATOM   2059 C CB  . LEU A 1 330  ? 95.289  119.287 116.611 1.00 41.64  ? 289  LEU A CB  1 
ATOM   2060 C CG  . LEU A 1 330  ? 95.081  118.991 115.131 1.00 41.64  ? 289  LEU A CG  1 
ATOM   2061 C CD1 . LEU A 1 330  ? 96.099  117.980 114.648 1.00 41.64  ? 289  LEU A CD1 1 
ATOM   2062 C CD2 . LEU A 1 330  ? 93.679  118.485 114.895 1.00 41.64  ? 289  LEU A CD2 1 
ATOM   2063 N N   . LEU A 1 331  ? 95.411  120.892 119.348 1.00 39.59  ? 290  LEU A N   1 
ATOM   2064 C CA  . LEU A 1 331  ? 95.589  120.888 120.793 1.00 39.59  ? 290  LEU A CA  1 
ATOM   2065 C C   . LEU A 1 331  ? 94.417  121.568 121.483 1.00 39.59  ? 290  LEU A C   1 
ATOM   2066 O O   . LEU A 1 331  ? 93.959  121.113 122.539 1.00 39.59  ? 290  LEU A O   1 
ATOM   2067 C CB  . LEU A 1 331  ? 96.907  121.565 121.155 1.00 39.59  ? 290  LEU A CB  1 
ATOM   2068 C CG  . LEU A 1 331  ? 98.151  120.771 120.760 1.00 39.59  ? 290  LEU A CG  1 
ATOM   2069 C CD1 . LEU A 1 331  ? 99.408  121.513 121.149 1.00 39.59  ? 290  LEU A CD1 1 
ATOM   2070 C CD2 . LEU A 1 331  ? 98.128  119.393 121.385 1.00 39.59  ? 290  LEU A CD2 1 
ATOM   2071 N N   . TRP A 1 332  ? 93.903  122.653 120.898 1.00 40.63  ? 291  TRP A N   1 
ATOM   2072 C CA  . TRP A 1 332  ? 92.720  123.275 121.484 1.00 40.63  ? 291  TRP A CA  1 
ATOM   2073 C C   . TRP A 1 332  ? 91.533  122.320 121.466 1.00 40.63  ? 291  TRP A C   1 
ATOM   2074 O O   . TRP A 1 332  ? 90.795  122.205 122.453 1.00 40.63  ? 291  TRP A O   1 
ATOM   2075 C CB  . TRP A 1 332  ? 92.372  124.570 120.756 1.00 40.63  ? 291  TRP A CB  1 
ATOM   2076 C CG  . TRP A 1 332  ? 91.180  125.235 121.357 1.00 40.63  ? 291  TRP A CG  1 
ATOM   2077 C CD1 . TRP A 1 332  ? 91.182  126.204 122.311 1.00 40.63  ? 291  TRP A CD1 1 
ATOM   2078 C CD2 . TRP A 1 332  ? 89.805  124.972 121.055 1.00 40.63  ? 291  TRP A CD2 1 
ATOM   2079 N NE1 . TRP A 1 332  ? 89.896  126.565 122.623 1.00 40.63  ? 291  TRP A NE1 1 
ATOM   2080 C CE2 . TRP A 1 332  ? 89.032  125.821 121.864 1.00 40.63  ? 291  TRP A CE2 1 
ATOM   2081 C CE3 . TRP A 1 332  ? 89.155  124.102 120.177 1.00 40.63  ? 291  TRP A CE3 1 
ATOM   2082 C CZ2 . TRP A 1 332  ? 87.643  125.828 121.823 1.00 40.63  ? 291  TRP A CZ2 1 
ATOM   2083 C CZ3 . TRP A 1 332  ? 87.777  124.108 120.138 1.00 40.63  ? 291  TRP A CZ3 1 
ATOM   2084 C CH2 . TRP A 1 332  ? 87.036  124.965 120.955 1.00 40.63  ? 291  TRP A CH2 1 
ATOM   2085 N N   . TYR A 1 333  ? 91.326  121.622 120.347 1.00 41.69  ? 292  TYR A N   1 
ATOM   2086 C CA  . TYR A 1 333  ? 90.194  120.704 120.275 1.00 41.69  ? 292  TYR A CA  1 
ATOM   2087 C C   . TYR A 1 333  ? 90.378  119.524 121.221 1.00 41.69  ? 292  TYR A C   1 
ATOM   2088 O O   . TYR A 1 333  ? 89.406  119.020 121.794 1.00 41.69  ? 292  TYR A O   1 
ATOM   2089 C CB  . TYR A 1 333  ? 89.989  120.222 118.843 1.00 41.69  ? 292  TYR A CB  1 
ATOM   2090 C CG  . TYR A 1 333  ? 88.707  119.455 118.665 1.00 41.69  ? 292  TYR A CG  1 
ATOM   2091 C CD1 . TYR A 1 333  ? 87.496  119.994 119.064 1.00 41.69  ? 292  TYR A CD1 1 
ATOM   2092 C CD2 . TYR A 1 333  ? 88.705  118.193 118.102 1.00 41.69  ? 292  TYR A CD2 1 
ATOM   2093 C CE1 . TYR A 1 333  ? 86.322  119.296 118.908 1.00 41.69  ? 292  TYR A CE1 1 
ATOM   2094 C CE2 . TYR A 1 333  ? 87.535  117.488 117.941 1.00 41.69  ? 292  TYR A CE2 1 
ATOM   2095 C CZ  . TYR A 1 333  ? 86.347  118.045 118.345 1.00 41.69  ? 292  TYR A CZ  1 
ATOM   2096 O OH  . TYR A 1 333  ? 85.178  117.343 118.185 1.00 41.69  ? 292  TYR A OH  1 
ATOM   2097 N N   . GLY A 1 334  ? 91.616  119.064 121.392 1.00 45.57  ? 293  GLY A N   1 
ATOM   2098 C CA  . GLY A 1 334  ? 91.873  118.011 122.359 1.00 45.57  ? 293  GLY A CA  1 
ATOM   2099 C C   . GLY A 1 334  ? 91.561  118.451 123.774 1.00 45.57  ? 293  GLY A C   1 
ATOM   2100 O O   . GLY A 1 334  ? 91.008  117.689 124.569 1.00 45.57  ? 293  GLY A O   1 
ATOM   2101 N N   . GLY A 1 335  ? 91.915  119.692 124.110 1.00 45.67  ? 294  GLY A N   1 
ATOM   2102 C CA  . GLY A 1 335  ? 91.522  120.230 125.401 1.00 45.67  ? 294  GLY A CA  1 
ATOM   2103 C C   . GLY A 1 335  ? 90.016  120.297 125.562 1.00 45.67  ? 294  GLY A C   1 
ATOM   2104 O O   . GLY A 1 335  ? 89.481  119.989 126.630 1.00 45.67  ? 294  GLY A O   1 
ATOM   2105 N N   . TYR A 1 336  ? 89.315  120.697 124.503 1.00 44.12  ? 295  TYR A N   1 
ATOM   2106 C CA  . TYR A 1 336  ? 87.857  120.746 124.558 1.00 44.12  ? 295  TYR A CA  1 
ATOM   2107 C C   . TYR A 1 336  ? 87.272  119.363 124.814 1.00 44.12  ? 295  TYR A C   1 
ATOM   2108 O O   . TYR A 1 336  ? 86.340  119.207 125.609 1.00 44.12  ? 295  TYR A O   1 
ATOM   2109 C CB  . TYR A 1 336  ? 87.300  121.323 123.261 1.00 44.12  ? 295  TYR A CB  1 
ATOM   2110 C CG  . TYR A 1 336  ? 85.805  121.185 123.140 1.00 44.12  ? 295  TYR A CG  1 
ATOM   2111 C CD1 . TYR A 1 336  ? 84.955  121.969 123.901 1.00 44.12  ? 295  TYR A CD1 1 
ATOM   2112 C CD2 . TYR A 1 336  ? 85.243  120.260 122.276 1.00 44.12  ? 295  TYR A CD2 1 
ATOM   2113 C CE1 . TYR A 1 336  ? 83.586  121.846 123.795 1.00 44.12  ? 295  TYR A CE1 1 
ATOM   2114 C CE2 . TYR A 1 336  ? 83.876  120.128 122.165 1.00 44.12  ? 295  TYR A CE2 1 
ATOM   2115 C CZ  . TYR A 1 336  ? 83.053  120.922 122.928 1.00 44.12  ? 295  TYR A CZ  1 
ATOM   2116 O OH  . TYR A 1 336  ? 81.689  120.794 122.822 1.00 44.12  ? 295  TYR A OH  1 
ATOM   2117 N N   . LEU A 1 337  ? 87.801  118.346 124.136 1.00 43.94  ? 296  LEU A N   1 
ATOM   2118 C CA  . LEU A 1 337  ? 87.309  116.986 124.340 1.00 43.94  ? 296  LEU A CA  1 
ATOM   2119 C C   . LEU A 1 337  ? 87.632  116.479 125.739 1.00 43.94  ? 296  LEU A C   1 
ATOM   2120 O O   . LEU A 1 337  ? 86.818  115.781 126.353 1.00 43.94  ? 296  LEU A O   1 
ATOM   2121 C CB  . LEU A 1 337  ? 87.892  116.047 123.288 1.00 43.94  ? 296  LEU A CB  1 
ATOM   2122 C CG  . LEU A 1 337  ? 87.479  116.313 121.845 1.00 43.94  ? 296  LEU A CG  1 
ATOM   2123 C CD1 . LEU A 1 337  ? 87.944  115.178 120.958 1.00 43.94  ? 296  LEU A CD1 1 
ATOM   2124 C CD2 . LEU A 1 337  ? 85.979  116.482 121.752 1.00 43.94  ? 296  LEU A CD2 1 
ATOM   2125 N N   . VAL A 1 338  ? 88.817  116.804 126.256 1.00 43.12  ? 297  VAL A N   1 
ATOM   2126 C CA  . VAL A 1 338  ? 89.183  116.376 127.603 1.00 43.12  ? 297  VAL A CA  1 
ATOM   2127 C C   . VAL A 1 338  ? 88.272  117.031 128.633 1.00 43.12  ? 297  VAL A C   1 
ATOM   2128 O O   . VAL A 1 338  ? 87.922  116.420 129.650 1.00 43.12  ? 297  VAL A O   1 
ATOM   2129 C CB  . VAL A 1 338  ? 90.668  116.680 127.872 1.00 43.12  ? 297  VAL A CB  1 
ATOM   2130 C CG1 . VAL A 1 338  ? 90.977  116.597 129.352 1.00 43.12  ? 297  VAL A CG1 1 
ATOM   2131 C CG2 . VAL A 1 338  ? 91.543  115.717 127.101 1.00 43.12  ? 297  VAL A CG2 1 
ATOM   2132 N N   . ARG A 1 339  ? 87.863  118.277 128.383 1.00 47.71  ? 298  ARG A N   1 
ATOM   2133 C CA  . ARG A 1 339  ? 86.937  118.948 129.291 1.00 47.71  ? 298  ARG A CA  1 
ATOM   2134 C C   . ARG A 1 339  ? 85.637  118.172 129.434 1.00 47.71  ? 298  ARG A C   1 
ATOM   2135 O O   . ARG A 1 339  ? 85.104  118.036 130.540 1.00 47.71  ? 298  ARG A O   1 
ATOM   2136 C CB  . ARG A 1 339  ? 86.637  120.360 128.797 1.00 47.71  ? 298  ARG A CB  1 
ATOM   2137 C CG  . ARG A 1 339  ? 87.619  121.402 129.253 1.00 47.71  ? 298  ARG A CG  1 
ATOM   2138 C CD  . ARG A 1 339  ? 87.275  122.762 128.682 1.00 47.71  ? 298  ARG A CD  1 
ATOM   2139 N NE  . ARG A 1 339  ? 87.869  122.991 127.371 1.00 47.71  ? 298  ARG A NE  1 
ATOM   2140 C CZ  . ARG A 1 339  ? 89.169  123.128 127.140 1.00 47.71  ? 298  ARG A CZ  1 
ATOM   2141 N NH1 . ARG A 1 339  ? 90.059  123.036 128.114 1.00 47.71  ? 298  ARG A NH1 1 
ATOM   2142 N NH2 . ARG A 1 339  ? 89.585  123.364 125.900 1.00 47.71  ? 298  ARG A NH2 1 
ATOM   2143 N N   . HIS A 1 340  ? 85.110  117.659 128.329 1.00 51.01  ? 299  HIS A N   1 
ATOM   2144 C CA  . HIS A 1 340  ? 83.814  117.001 128.320 1.00 51.01  ? 299  HIS A CA  1 
ATOM   2145 C C   . HIS A 1 340  ? 83.907  115.502 128.569 1.00 51.01  ? 299  HIS A C   1 
ATOM   2146 O O   . HIS A 1 340  ? 82.957  114.777 128.258 1.00 51.01  ? 299  HIS A O   1 
ATOM   2147 C CB  . HIS A 1 340  ? 83.103  117.277 126.997 1.00 51.01  ? 299  HIS A CB  1 
ATOM   2148 C CG  . HIS A 1 340  ? 82.619  118.684 126.865 1.00 51.01  ? 299  HIS A CG  1 
ATOM   2149 N ND1 . HIS A 1 340  ? 83.445  119.773 127.040 1.00 51.01  ? 299  HIS A ND1 1 
ATOM   2150 C CD2 . HIS A 1 340  ? 81.392  119.185 126.589 1.00 51.01  ? 299  HIS A CD2 1 
ATOM   2151 C CE1 . HIS A 1 340  ? 82.750  120.882 126.872 1.00 51.01  ? 299  HIS A CE1 1 
ATOM   2152 N NE2 . HIS A 1 340  ? 81.501  120.554 126.596 1.00 51.01  ? 299  HIS A NE2 1 
ATOM   2153 N N   . HIS A 1 341  ? 85.024  115.029 129.118 1.00 52.13  ? 300  HIS A N   1 
ATOM   2154 C CA  . HIS A 1 341  ? 85.188  113.635 129.523 1.00 52.13  ? 300  HIS A CA  1 
ATOM   2155 C C   . HIS A 1 341  ? 84.938  112.683 128.358 1.00 52.13  ? 300  HIS A C   1 
ATOM   2156 O O   . HIS A 1 341  ? 84.343  111.614 128.507 1.00 52.13  ? 300  HIS A O   1 
ATOM   2157 C CB  . HIS A 1 341  ? 84.278  113.309 130.706 1.00 52.13  ? 300  HIS A CB  1 
ATOM   2158 C CG  . HIS A 1 341  ? 84.304  114.342 131.786 1.00 52.13  ? 300  HIS A CG  1 
ATOM   2159 N ND1 . HIS A 1 341  ? 85.435  114.620 132.522 1.00 52.13  ? 300  HIS A ND1 1 
ATOM   2160 C CD2 . HIS A 1 341  ? 83.342  115.176 132.246 1.00 52.13  ? 300  HIS A CD2 1 
ATOM   2161 C CE1 . HIS A 1 341  ? 85.167  115.574 133.395 1.00 52.13  ? 300  HIS A CE1 1 
ATOM   2162 N NE2 . HIS A 1 341  ? 83.904  115.930 133.247 1.00 52.13  ? 300  HIS A NE2 1 
ATOM   2163 N N   . LEU A 1 342  ? 85.400  113.086 127.176 1.00 48.24  ? 301  LEU A N   1 
ATOM   2164 C CA  . LEU A 1 342  ? 85.268  112.270 125.981 1.00 48.24  ? 301  LEU A CA  1 
ATOM   2165 C C   . LEU A 1 342  ? 86.539  111.512 125.632 1.00 48.24  ? 301  LEU A C   1 
ATOM   2166 O O   . LEU A 1 342  ? 86.505  110.673 124.727 1.00 48.24  ? 301  LEU A O   1 
ATOM   2167 C CB  . LEU A 1 342  ? 84.855  113.137 124.788 1.00 48.24  ? 301  LEU A CB  1 
ATOM   2168 C CG  . LEU A 1 342  ? 83.474  113.781 124.878 1.00 48.24  ? 301  LEU A CG  1 
ATOM   2169 C CD1 . LEU A 1 342  ? 83.156  114.545 123.609 1.00 48.24  ? 301  LEU A CD1 1 
ATOM   2170 C CD2 . LEU A 1 342  ? 82.424  112.721 125.136 1.00 48.24  ? 301  LEU A CD2 1 
ATOM   2171 N N   . THR A 1 343  ? 87.644  111.774 126.324 1.00 46.60  ? 302  THR A N   1 
ATOM   2172 C CA  . THR A 1 343  ? 88.907  111.115 126.025 1.00 46.60  ? 302  THR A CA  1 
ATOM   2173 C C   . THR A 1 343  ? 89.898  111.386 127.145 1.00 46.60  ? 302  THR A C   1 
ATOM   2174 O O   . THR A 1 343  ? 89.566  111.983 128.171 1.00 46.60  ? 302  THR A O   1 
ATOM   2175 C CB  . THR A 1 343  ? 89.484  111.580 124.687 1.00 46.60  ? 302  THR A CB  1 
ATOM   2176 O OG1 . THR A 1 343  ? 90.631  110.784 124.367 1.00 46.60  ? 302  THR A OG1 1 
ATOM   2177 C CG2 . THR A 1 343  ? 89.888  113.041 124.755 1.00 46.60  ? 302  THR A CG2 1 
ATOM   2178 N N   . ASN A 1 344  ? 91.124  110.924 126.933 1.00 46.08  ? 303  ASN A N   1 
ATOM   2179 C CA  . ASN A 1 344  ? 92.255  111.216 127.796 1.00 46.08  ? 303  ASN A CA  1 
ATOM   2180 C C   . ASN A 1 344  ? 93.236  112.124 127.068 1.00 46.08  ? 303  ASN A C   1 
ATOM   2181 O O   . ASN A 1 344  ? 93.082  112.422 125.882 1.00 46.08  ? 303  ASN A O   1 
ATOM   2182 C CB  . ASN A 1 344  ? 92.958  109.928 128.226 1.00 46.08  ? 303  ASN A CB  1 
ATOM   2183 C CG  . ASN A 1 344  ? 91.990  108.860 128.668 1.00 46.08  ? 303  ASN A CG  1 
ATOM   2184 O OD1 . ASN A 1 344  ? 91.186  109.071 129.574 1.00 46.08  ? 303  ASN A OD1 1 
ATOM   2185 N ND2 . ASN A 1 344  ? 92.062  107.700 128.031 1.00 46.08  ? 303  ASN A ND2 1 
ATOM   2186 N N   . GLY A 1 345  ? 94.257  112.571 127.799 1.00 45.03  ? 304  GLY A N   1 
ATOM   2187 C CA  . GLY A 1 345  ? 95.280  113.394 127.177 1.00 45.03  ? 304  GLY A CA  1 
ATOM   2188 C C   . GLY A 1 345  ? 96.183  112.596 126.256 1.00 45.03  ? 304  GLY A C   1 
ATOM   2189 O O   . GLY A 1 345  ? 96.362  112.941 125.082 1.00 45.03  ? 304  GLY A O   1 
ATOM   2190 N N   . GLY A 1 346  ? 96.765  111.517 126.780 1.00 43.03  ? 305  GLY A N   1 
ATOM   2191 C CA  . GLY A 1 346  ? 97.634  110.689 125.965 1.00 43.03  ? 305  GLY A CA  1 
ATOM   2192 C C   . GLY A 1 346  ? 96.916  110.102 124.770 1.00 43.03  ? 305  GLY A C   1 
ATOM   2193 O O   . GLY A 1 346  ? 97.488  109.984 123.685 1.00 43.03  ? 305  GLY A O   1 
ATOM   2194 N N   . LEU A 1 347  ? 95.644  109.743 124.948 1.00 42.19  ? 306  LEU A N   1 
ATOM   2195 C CA  . LEU A 1 347  ? 94.860  109.198 123.846 1.00 42.19  ? 306  LEU A CA  1 
ATOM   2196 C C   . LEU A 1 347  ? 94.706  110.221 122.726 1.00 42.19  ? 306  LEU A C   1 
ATOM   2197 O O   . LEU A 1 347  ? 94.859  109.892 121.546 1.00 42.19  ? 306  LEU A O   1 
ATOM   2198 C CB  . LEU A 1 347  ? 93.497  108.747 124.365 1.00 42.19  ? 306  LEU A CB  1 
ATOM   2199 C CG  . LEU A 1 347  ? 92.812  107.593 123.644 1.00 42.19  ? 306  LEU A CG  1 
ATOM   2200 C CD1 . LEU A 1 347  ? 93.507  106.294 123.989 1.00 42.19  ? 306  LEU A CD1 1 
ATOM   2201 C CD2 . LEU A 1 347  ? 91.349  107.532 124.030 1.00 42.19  ? 306  LEU A CD2 1 
ATOM   2202 N N   . ALA A 1 348  ? 94.428  111.476 123.082 1.00 40.03  ? 307  ALA A N   1 
ATOM   2203 C CA  . ALA A 1 348  ? 94.269  112.523 122.074 1.00 40.03  ? 307  ALA A CA  1 
ATOM   2204 C C   . ALA A 1 348  ? 95.585  112.810 121.358 1.00 40.03  ? 307  ALA A C   1 
ATOM   2205 O O   . ALA A 1 348  ? 95.624  112.947 120.126 1.00 40.03  ? 307  ALA A O   1 
ATOM   2206 C CB  . ALA A 1 348  ? 93.723  113.789 122.728 1.00 40.03  ? 307  ALA A CB  1 
ATOM   2207 N N   . ILE A 1 349  ? 96.677  112.911 122.120 1.00 39.96  ? 308  ILE A N   1 
ATOM   2208 C CA  . ILE A 1 349  ? 97.979  113.164 121.507 1.00 39.96  ? 308  ILE A CA  1 
ATOM   2209 C C   . ILE A 1 349  ? 98.337  112.040 120.544 1.00 39.96  ? 308  ILE A C   1 
ATOM   2210 O O   . ILE A 1 349  ? 98.785  112.278 119.413 1.00 39.96  ? 308  ILE A O   1 
ATOM   2211 C CB  . ILE A 1 349  ? 99.054  113.345 122.592 1.00 39.96  ? 308  ILE A CB  1 
ATOM   2212 C CG1 . ILE A 1 349  ? 98.859  114.674 123.316 1.00 39.96  ? 308  ILE A CG1 1 
ATOM   2213 C CG2 . ILE A 1 349  ? 100.440 113.274 121.989 1.00 39.96  ? 308  ILE A CG2 1 
ATOM   2214 C CD1 . ILE A 1 349  ? 99.029  115.879 122.428 1.00 39.96  ? 308  ILE A CD1 1 
ATOM   2215 N N   . ALA A 1 350  ? 98.131  110.793 120.973 1.00 38.90  ? 309  ALA A N   1 
ATOM   2216 C CA  . ALA A 1 350  ? 98.442  109.656 120.120 1.00 38.90  ? 309  ALA A CA  1 
ATOM   2217 C C   . ALA A 1 350  ? 97.550  109.623 118.891 1.00 38.90  ? 309  ALA A C   1 
ATOM   2218 O O   . ALA A 1 350  ? 97.992  109.218 117.816 1.00 38.90  ? 309  ALA A O   1 
ATOM   2219 C CB  . ALA A 1 350  ? 98.310  108.357 120.905 1.00 38.90  ? 309  ALA A CB  1 
ATOM   2220 N N   . THR A 1 351  ? 96.288  110.034 119.027 1.00 37.90  ? 310  THR A N   1 
ATOM   2221 C CA  . THR A 1 351  ? 95.407  110.078 117.865 1.00 37.90  ? 310  THR A CA  1 
ATOM   2222 C C   . THR A 1 351  ? 95.922  111.064 116.826 1.00 37.90  ? 310  THR A C   1 
ATOM   2223 O O   . THR A 1 351  ? 95.997  110.745 115.629 1.00 37.90  ? 310  THR A O   1 
ATOM   2224 C CB  . THR A 1 351  ? 93.991  110.448 118.296 1.00 37.90  ? 310  THR A CB  1 
ATOM   2225 O OG1 . THR A 1 351  ? 93.463  109.415 119.134 1.00 37.90  ? 310  THR A OG1 1 
ATOM   2226 C CG2 . THR A 1 351  ? 93.098  110.615 117.085 1.00 37.90  ? 310  THR A CG2 1 
ATOM   2227 N N   . MET A 1 352  ? 96.292  112.267 117.269 1.00 39.40  ? 311  MET A N   1 
ATOM   2228 C CA  . MET A 1 352  ? 96.842  113.251 116.339 1.00 39.40  ? 311  MET A CA  1 
ATOM   2229 C C   . MET A 1 352  ? 98.088  112.711 115.652 1.00 39.40  ? 311  MET A C   1 
ATOM   2230 O O   . MET A 1 352  ? 98.217  112.770 114.418 1.00 39.40  ? 311  MET A O   1 
ATOM   2231 C CB  . MET A 1 352  ? 97.160  114.553 117.070 1.00 39.40  ? 311  MET A CB  1 
ATOM   2232 C CG  . MET A 1 352  ? 95.985  115.161 117.800 1.00 39.40  ? 311  MET A CG  1 
ATOM   2233 S SD  . MET A 1 352  ? 96.491  116.152 119.212 1.00 39.40  ? 311  MET A SD  1 
ATOM   2234 C CE  . MET A 1 352  ? 97.813  117.104 118.483 1.00 39.40  ? 311  MET A CE  1 
ATOM   2235 N N   . PHE A 1 353  ? 99.010  112.154 116.440 1.00 36.82  ? 312  PHE A N   1 
ATOM   2236 C CA  . PHE A 1 353  ? 100.252 111.644 115.873 1.00 36.82  ? 312  PHE A CA  1 
ATOM   2237 C C   . PHE A 1 353  ? 99.990  110.514 114.886 1.00 36.82  ? 312  PHE A C   1 
ATOM   2238 O O   . PHE A 1 353  ? 100.598 110.467 113.812 1.00 36.82  ? 312  PHE A O   1 
ATOM   2239 C CB  . PHE A 1 353  ? 101.183 111.179 116.989 1.00 36.82  ? 312  PHE A CB  1 
ATOM   2240 C CG  . PHE A 1 353  ? 101.823 112.300 117.751 1.00 36.82  ? 312  PHE A CG  1 
ATOM   2241 C CD1 . PHE A 1 353  ? 101.659 113.611 117.348 1.00 36.82  ? 312  PHE A CD1 1 
ATOM   2242 C CD2 . PHE A 1 353  ? 102.581 112.044 118.875 1.00 36.82  ? 312  PHE A CD2 1 
ATOM   2243 C CE1 . PHE A 1 353  ? 102.245 114.641 118.048 1.00 36.82  ? 312  PHE A CE1 1 
ATOM   2244 C CE2 . PHE A 1 353  ? 103.168 113.071 119.577 1.00 36.82  ? 312  PHE A CE2 1 
ATOM   2245 C CZ  . PHE A 1 353  ? 102.999 114.370 119.162 1.00 36.82  ? 312  PHE A CZ  1 
ATOM   2246 N N   . ALA A 1 354  ? 99.080  109.601 115.224 1.00 36.88  ? 313  ALA A N   1 
ATOM   2247 C CA  . ALA A 1 354  ? 98.824  108.445 114.374 1.00 36.88  ? 313  ALA A CA  1 
ATOM   2248 C C   . ALA A 1 354  ? 98.205  108.858 113.048 1.00 36.88  ? 313  ALA A C   1 
ATOM   2249 O O   . ALA A 1 354  ? 98.565  108.326 111.991 1.00 36.88  ? 313  ALA A O   1 
ATOM   2250 C CB  . ALA A 1 354  ? 97.923  107.450 115.102 1.00 36.88  ? 313  ALA A CB  1 
ATOM   2251 N N   . VAL A 1 355  ? 97.262  109.801 113.075 1.00 38.45  ? 314  VAL A N   1 
ATOM   2252 C CA  . VAL A 1 355  ? 96.646  110.215 111.818 1.00 38.45  ? 314  VAL A CA  1 
ATOM   2253 C C   . VAL A 1 355  ? 97.654  110.956 110.944 1.00 38.45  ? 314  VAL A C   1 
ATOM   2254 O O   . VAL A 1 355  ? 97.699  110.759 109.718 1.00 38.45  ? 314  VAL A O   1 
ATOM   2255 C CB  . VAL A 1 355  ? 95.382  111.049 112.081 1.00 38.45  ? 314  VAL A CB  1 
ATOM   2256 C CG1 . VAL A 1 355  ? 94.772  111.498 110.772 1.00 38.45  ? 314  VAL A CG1 1 
ATOM   2257 C CG2 . VAL A 1 355  ? 94.381  110.233 112.866 1.00 38.45  ? 314  VAL A CG2 1 
ATOM   2258 N N   . MET A 1 356  ? 98.490  111.808 111.554 1.00 39.50  ? 315  MET A N   1 
ATOM   2259 C CA  . MET A 1 356  ? 99.566  112.434 110.788 1.00 39.50  ? 315  MET A CA  1 
ATOM   2260 C C   . MET A 1 356  ? 100.473 111.389 110.151 1.00 39.50  ? 315  MET A C   1 
ATOM   2261 O O   . MET A 1 356  ? 100.833 111.496 108.971 1.00 39.50  ? 315  MET A O   1 
ATOM   2262 C CB  . MET A 1 356  ? 100.385 113.369 111.674 1.00 39.50  ? 315  MET A CB  1 
ATOM   2263 C CG  . MET A 1 356  ? 99.655  114.583 112.195 1.00 39.50  ? 315  MET A CG  1 
ATOM   2264 S SD  . MET A 1 356  ? 99.172  115.656 110.830 1.00 39.50  ? 315  MET A SD  1 
ATOM   2265 C CE  . MET A 1 356  ? 98.157  116.858 111.676 1.00 39.50  ? 315  MET A CE  1 
ATOM   2266 N N   . ILE A 1 357  ? 100.853 110.368 110.921 1.00 40.89  ? 316  ILE A N   1 
ATOM   2267 C CA  . ILE A 1 357  ? 101.755 109.344 110.408 1.00 40.89  ? 316  ILE A CA  1 
ATOM   2268 C C   . ILE A 1 357  ? 101.117 108.606 109.239 1.00 40.89  ? 316  ILE A C   1 
ATOM   2269 O O   . ILE A 1 357  ? 101.772 108.339 108.227 1.00 40.89  ? 316  ILE A O   1 
ATOM   2270 C CB  . ILE A 1 357  ? 102.166 108.383 111.537 1.00 40.89  ? 316  ILE A CB  1 
ATOM   2271 C CG1 . ILE A 1 357  ? 103.062 109.105 112.540 1.00 40.89  ? 316  ILE A CG1 1 
ATOM   2272 C CG2 . ILE A 1 357  ? 102.893 107.185 110.981 1.00 40.89  ? 316  ILE A CG2 1 
ATOM   2273 C CD1 . ILE A 1 357  ? 104.270 109.751 111.917 1.00 40.89  ? 316  ILE A CD1 1 
ATOM   2274 N N   . GLY A 1 358  ? 99.830  108.276 109.350 1.00 41.80  ? 317  GLY A N   1 
ATOM   2275 C CA  . GLY A 1 358  ? 99.161  107.582 108.260 1.00 41.80  ? 317  GLY A CA  1 
ATOM   2276 C C   . GLY A 1 358  ? 99.108  108.401 106.982 1.00 41.80  ? 317  GLY A C   1 
ATOM   2277 O O   . GLY A 1 358  ? 99.396  107.897 105.886 1.00 41.80  ? 317  GLY A O   1 
ATOM   2278 N N   . GLY A 1 359  ? 98.732  109.676 107.100 1.00 42.04  ? 318  GLY A N   1 
ATOM   2279 C CA  . GLY A 1 359  ? 98.695  110.521 105.916 1.00 42.04  ? 318  GLY A CA  1 
ATOM   2280 C C   . GLY A 1 359  ? 100.056 110.662 105.259 1.00 42.04  ? 318  GLY A C   1 
ATOM   2281 O O   . GLY A 1 359  ? 100.192 110.529 104.033 1.00 42.04  ? 318  GLY A O   1 
ATOM   2282 N N   . LEU A 1 360  ? 101.088 110.913 106.066 1.00 42.54  ? 319  LEU A N   1 
ATOM   2283 C CA  . LEU A 1 360  ? 102.429 111.027 105.510 1.00 42.54  ? 319  LEU A CA  1 
ATOM   2284 C C   . LEU A 1 360  ? 102.881 109.710 104.892 1.00 42.54  ? 319  LEU A C   1 
ATOM   2285 O O   . LEU A 1 360  ? 103.629 109.703 103.909 1.00 42.54  ? 319  LEU A O   1 
ATOM   2286 C CB  . LEU A 1 360  ? 103.404 111.491 106.591 1.00 42.54  ? 319  LEU A CB  1 
ATOM   2287 C CG  . LEU A 1 360  ? 103.060 112.841 107.224 1.00 42.54  ? 319  LEU A CG  1 
ATOM   2288 C CD1 . LEU A 1 360  ? 104.197 113.338 108.096 1.00 42.54  ? 319  LEU A CD1 1 
ATOM   2289 C CD2 . LEU A 1 360  ? 102.697 113.869 106.167 1.00 42.54  ? 319  LEU A CD2 1 
ATOM   2290 N N   . ALA A 1 361  ? 102.424 108.583 105.442 1.00 42.32  ? 320  ALA A N   1 
ATOM   2291 C CA  . ALA A 1 361  ? 102.776 107.288 104.875 1.00 42.32  ? 320  ALA A CA  1 
ATOM   2292 C C   . ALA A 1 361  ? 102.194 107.116 103.480 1.00 42.32  ? 320  ALA A C   1 
ATOM   2293 O O   . ALA A 1 361  ? 102.877 106.636 102.571 1.00 42.32  ? 320  ALA A O   1 
ATOM   2294 C CB  . ALA A 1 361  ? 102.300 106.167 105.795 1.00 42.32  ? 320  ALA A CB  1 
ATOM   2295 N N   . LEU A 1 362  ? 100.931 107.497 103.291 1.00 43.37  ? 321  LEU A N   1 
ATOM   2296 C CA  . LEU A 1 362  ? 100.349 107.416 101.950 1.00 43.37  ? 321  LEU A CA  1 
ATOM   2297 C C   . LEU A 1 362  ? 101.104 108.315 100.970 1.00 43.37  ? 321  LEU A C   1 
ATOM   2298 O O   . LEU A 1 362  ? 101.420 107.911 99.827  1.00 43.37  ? 321  LEU A O   1 
ATOM   2299 C CB  . LEU A 1 362  ? 98.872  107.796 102.006 1.00 43.37  ? 321  LEU A CB  1 
ATOM   2300 C CG  . LEU A 1 362  ? 98.044  107.587 100.741 1.00 43.37  ? 321  LEU A CG  1 
ATOM   2301 C CD1 . LEU A 1 362  ? 97.683  106.122 100.598 1.00 43.37  ? 321  LEU A CD1 1 
ATOM   2302 C CD2 . LEU A 1 362  ? 96.794  108.445 100.772 1.00 43.37  ? 321  LEU A CD2 1 
ATOM   2303 N N   . GLY A 1 363  ? 101.415 109.537 101.411 1.00 42.96  ? 322  GLY A N   1 
ATOM   2304 C CA  . GLY A 1 363  ? 102.197 110.432 100.576 1.00 42.96  ? 322  GLY A CA  1 
ATOM   2305 C C   . GLY A 1 363  ? 103.534 109.838 100.173 1.00 42.96  ? 322  GLY A C   1 
ATOM   2306 O O   . GLY A 1 363  ? 103.949 109.946 99.018  1.00 42.96  ? 322  GLY A O   1 
ATOM   2307 N N   . GLN A 1 364  ? 104.221 109.193 101.118 1.00 44.54  ? 323  GLN A N   1 
ATOM   2308 C CA  . GLN A 1 364  ? 105.503 108.570 100.813 1.00 44.54  ? 323  GLN A CA  1 
ATOM   2309 C C   . GLN A 1 364  ? 105.353 107.308 99.977  1.00 44.54  ? 323  GLN A C   1 
ATOM   2310 O O   . GLN A 1 364  ? 106.327 106.870 99.358  1.00 44.54  ? 323  GLN A O   1 
ATOM   2311 C CB  . GLN A 1 364  ? 106.251 108.238 102.102 1.00 44.54  ? 323  GLN A CB  1 
ATOM   2312 C CG  . GLN A 1 364  ? 106.590 109.441 102.953 1.00 44.54  ? 323  GLN A CG  1 
ATOM   2313 C CD  . GLN A 1 364  ? 107.050 109.051 104.339 1.00 44.54  ? 323  GLN A CD  1 
ATOM   2314 O OE1 . GLN A 1 364  ? 108.088 108.414 104.504 1.00 44.54  ? 323  GLN A OE1 1 
ATOM   2315 N NE2 . GLN A 1 364  ? 106.276 109.426 105.347 1.00 44.54  ? 323  GLN A NE2 1 
ATOM   2316 N N   . SER A 1 365  ? 104.169 106.699 99.970  1.00 46.55  ? 324  SER A N   1 
ATOM   2317 C CA  . SER A 1 365  ? 103.946 105.503 99.169  1.00 46.55  ? 324  SER A CA  1 
ATOM   2318 C C   . SER A 1 365  ? 103.762 105.802 97.690  1.00 46.55  ? 324  SER A C   1 
ATOM   2319 O O   . SER A 1 365  ? 104.083 104.945 96.861  1.00 46.55  ? 324  SER A O   1 
ATOM   2320 C CB  . SER A 1 365  ? 102.719 104.755 99.671  1.00 46.55  ? 324  SER A CB  1 
ATOM   2321 O OG  . SER A 1 365  ? 101.542 105.412 99.239  1.00 46.55  ? 324  SER A OG  1 
ATOM   2322 N N   . ALA A 1 366  ? 103.224 106.972 97.344  1.00 48.80  ? 325  ALA A N   1 
ATOM   2323 C CA  . ALA A 1 366  ? 103.023 107.291 95.923  1.00 48.80  ? 325  ALA A CA  1 
ATOM   2324 C C   . ALA A 1 366  ? 104.269 107.112 95.038  1.00 48.80  ? 325  ALA A C   1 
ATOM   2325 O O   . ALA A 1 366  ? 104.131 106.618 93.894  1.00 48.80  ? 325  ALA A O   1 
ATOM   2326 C CB  . ALA A 1 366  ? 102.465 108.712 95.797  1.00 48.80  ? 325  ALA A CB  1 
ATOM   2327 N N   . PRO A 1 367  ? 105.483 107.499 95.460  1.00 49.04  ? 326  PRO A N   1 
ATOM   2328 C CA  . PRO A 1 367  ? 106.655 107.282 94.588  1.00 49.04  ? 326  PRO A CA  1 
ATOM   2329 C C   . PRO A 1 367  ? 106.862 105.835 94.170  1.00 49.04  ? 326  PRO A C   1 
ATOM   2330 O O   . PRO A 1 367  ? 107.404 105.573 93.086  1.00 49.04  ? 326  PRO A O   1 
ATOM   2331 C CB  . PRO A 1 367  ? 107.814 107.792 95.449  1.00 49.04  ? 326  PRO A CB  1 
ATOM   2332 C CG  . PRO A 1 367  ? 107.212 108.831 96.287  1.00 49.04  ? 326  PRO A CG  1 
ATOM   2333 C CD  . PRO A 1 367  ? 105.822 108.367 96.601  1.00 49.04  ? 326  PRO A CD  1 
ATOM   2334 N N   . SER A 1 368  ? 106.457 104.883 95.009  1.00 49.67  ? 327  SER A N   1 
ATOM   2335 C CA  . SER A 1 368  ? 106.533 103.483 94.614  1.00 49.67  ? 327  SER A CA  1 
ATOM   2336 C C   . SER A 1 368  ? 105.657 103.210 93.402  1.00 49.67  ? 327  SER A C   1 
ATOM   2337 O O   . SER A 1 368  ? 106.033 102.434 92.519  1.00 49.67  ? 327  SER A O   1 
ATOM   2338 C CB  . SER A 1 368  ? 106.142 102.583 95.782  1.00 49.67  ? 327  SER A CB  1 
ATOM   2339 O OG  . SER A 1 368  ? 107.029 102.760 96.870  1.00 49.67  ? 327  SER A OG  1 
ATOM   2340 N N   . MET A 1 369  ? 104.480 103.838 93.337  1.00 51.70  ? 328  MET A N   1 
ATOM   2341 C CA  . MET A 1 369  ? 103.639 103.700 92.153  1.00 51.70  ? 328  MET A CA  1 
ATOM   2342 C C   . MET A 1 369  ? 104.322 104.285 90.925  1.00 51.70  ? 328  MET A C   1 
ATOM   2343 O O   . MET A 1 369  ? 104.261 103.705 89.826  1.00 51.70  ? 328  MET A O   1 
ATOM   2344 C CB  . MET A 1 369  ? 102.288 104.369 92.389  1.00 51.70  ? 328  MET A CB  1 
ATOM   2345 C CG  . MET A 1 369  ? 101.304 103.508 93.151  1.00 51.70  ? 328  MET A CG  1 
ATOM   2346 S SD  . MET A 1 369  ? 100.496 102.305 92.085  1.00 51.70  ? 328  MET A SD  1 
ATOM   2347 C CE  . MET A 1 369  ? 99.629  101.309 93.292  1.00 51.70  ? 328  MET A CE  1 
ATOM   2348 N N   . ALA A 1 370  ? 104.983 105.434 91.087  1.00 51.61  ? 329  ALA A N   1 
ATOM   2349 C CA  . ALA A 1 370  ? 105.726 105.995 89.956  1.00 51.61  ? 329  ALA A CA  1 
ATOM   2350 C C   . ALA A 1 370  ? 106.787 105.016 89.453  1.00 51.61  ? 329  ALA A C   1 
ATOM   2351 O O   . ALA A 1 370  ? 106.918 104.771 88.239  1.00 51.61  ? 329  ALA A O   1 
ATOM   2352 C CB  . ALA A 1 370  ? 106.366 107.323 90.359  1.00 51.61  ? 329  ALA A CB  1 
ATOM   2353 N N   . ALA A 1 371  ? 107.548 104.436 90.383  1.00 51.13  ? 330  ALA A N   1 
ATOM   2354 C CA  . ALA A 1 371  ? 108.582 103.476 90.012  1.00 51.13  ? 330  ALA A CA  1 
ATOM   2355 C C   . ALA A 1 371  ? 107.982 102.246 89.348  1.00 51.13  ? 330  ALA A C   1 
ATOM   2356 O O   . ALA A 1 371  ? 108.575 101.681 88.421  1.00 51.13  ? 330  ALA A O   1 
ATOM   2357 C CB  . ALA A 1 371  ? 109.393 103.076 91.241  1.00 51.13  ? 330  ALA A CB  1 
ATOM   2358 N N   . PHE A 1 372  ? 106.812 101.806 89.817  1.00 54.22  ? 331  PHE A N   1 
ATOM   2359 C CA  . PHE A 1 372  ? 106.153 100.660 89.202  1.00 54.22  ? 331  PHE A CA  1 
ATOM   2360 C C   . PHE A 1 372  ? 105.826 100.935 87.744  1.00 54.22  ? 331  PHE A C   1 
ATOM   2361 O O   . PHE A 1 372  ? 106.031 100.074 86.883  1.00 54.22  ? 331  PHE A O   1 
ATOM   2362 C CB  . PHE A 1 372  ? 104.879 100.303 89.964  1.00 54.22  ? 331  PHE A CB  1 
ATOM   2363 C CG  . PHE A 1 372  ? 105.121 99.794  91.350  1.00 54.22  ? 331  PHE A CG  1 
ATOM   2364 C CD1 . PHE A 1 372  ? 106.331 99.223  91.691  1.00 54.22  ? 331  PHE A CD1 1 
ATOM   2365 C CD2 . PHE A 1 372  ? 104.135 99.887  92.313  1.00 54.22  ? 331  PHE A CD2 1 
ATOM   2366 C CE1 . PHE A 1 372  ? 106.551 98.758  92.968  1.00 54.22  ? 331  PHE A CE1 1 
ATOM   2367 C CE2 . PHE A 1 372  ? 104.350 99.423  93.588  1.00 54.22  ? 331  PHE A CE2 1 
ATOM   2368 C CZ  . PHE A 1 372  ? 105.559 98.858  93.916  1.00 54.22  ? 331  PHE A CZ  1 
ATOM   2369 N N   . ALA A 1 373  ? 105.316 102.133 87.445  1.00 55.52  ? 332  ALA A N   1 
ATOM   2370 C CA  . ALA A 1 373  ? 105.005 102.463 86.054  1.00 55.52  ? 332  ALA A CA  1 
ATOM   2371 C C   . ALA A 1 373  ? 106.264 102.457 85.187  1.00 55.52  ? 332  ALA A C   1 
ATOM   2372 O O   . ALA A 1 373  ? 106.287 101.866 84.090  1.00 55.52  ? 332  ALA A O   1 
ATOM   2373 C CB  . ALA A 1 373  ? 104.309 103.820 85.982  1.00 55.52  ? 332  ALA A CB  1 
ATOM   2374 N N   . LYS A 1 374  ? 107.328 103.109 85.668  1.00 58.85  ? 333  LYS A N   1 
ATOM   2375 C CA  . LYS A 1 374  ? 108.555 103.153 84.875  1.00 58.85  ? 333  LYS A CA  1 
ATOM   2376 C C   . LYS A 1 374  ? 109.107 101.752 84.628  1.00 58.85  ? 333  LYS A C   1 
ATOM   2377 O O   . LYS A 1 374  ? 109.524 101.423 83.506  1.00 58.85  ? 333  LYS A O   1 
ATOM   2378 C CB  . LYS A 1 374  ? 109.606 104.028 85.556  1.00 58.85  ? 333  LYS A CB  1 
ATOM   2379 C CG  . LYS A 1 374  ? 109.286 105.507 85.529  1.00 58.85  ? 333  LYS A CG  1 
ATOM   2380 C CD  . LYS A 1 374  ? 110.500 106.337 85.896  1.00 58.85  ? 333  LYS A CD  1 
ATOM   2381 C CE  . LYS A 1 374  ? 110.812 106.240 87.375  1.00 58.85  ? 333  LYS A CE  1 
ATOM   2382 N NZ  . LYS A 1 374  ? 111.932 107.143 87.756  1.00 58.85  ? 333  LYS A NZ  1 
ATOM   2383 N N   . ALA A 1 375  ? 109.103 100.908 85.658  1.00 57.85  ? 334  ALA A N   1 
ATOM   2384 C CA  . ALA A 1 375  ? 109.615 99.556  85.489  1.00 57.85  ? 334  ALA A CA  1 
ATOM   2385 C C   . ALA A 1 375  ? 108.718 98.721  84.593  1.00 57.85  ? 334  ALA A C   1 
ATOM   2386 O O   . ALA A 1 375  ? 109.207 97.812  83.920  1.00 57.85  ? 334  ALA A O   1 
ATOM   2387 C CB  . ALA A 1 375  ? 109.777 98.878  86.838  1.00 57.85  ? 334  ALA A CB  1 
ATOM   2388 N N   . LYS A 1 376  ? 107.413 98.989  84.578  1.00 60.99  ? 335  LYS A N   1 
ATOM   2389 C CA  . LYS A 1 376  ? 106.544 98.288  83.643  1.00 60.99  ? 335  LYS A CA  1 
ATOM   2390 C C   . LYS A 1 376  ? 106.953 98.581  82.207  1.00 60.99  ? 335  LYS A C   1 
ATOM   2391 O O   . LYS A 1 376  ? 107.064 97.668  81.379  1.00 60.99  ? 335  LYS A O   1 
ATOM   2392 C CB  . LYS A 1 376  ? 105.086 98.675  83.884  1.00 60.99  ? 335  LYS A CB  1 
ATOM   2393 C CG  . LYS A 1 376  ? 104.407 97.864  84.973  1.00 60.99  ? 335  LYS A CG  1 
ATOM   2394 C CD  . LYS A 1 376  ? 103.139 98.543  85.456  1.00 60.99  ? 335  LYS A CD  1 
ATOM   2395 C CE  . LYS A 1 376  ? 102.218 98.866  84.296  1.00 60.99  ? 335  LYS A CE  1 
ATOM   2396 N NZ  . LYS A 1 376  ? 100.990 99.573  84.747  1.00 60.99  ? 335  LYS A NZ  1 
ATOM   2397 N N   . VAL A 1 377  ? 107.216 99.853  81.901  1.00 64.30  ? 336  VAL A N   1 
ATOM   2398 C CA  . VAL A 1 377  ? 107.671 100.193 80.547  1.00 64.30  ? 336  VAL A CA  1 
ATOM   2399 C C   . VAL A 1 377  ? 109.000 99.504  80.232  1.00 64.30  ? 336  VAL A C   1 
ATOM   2400 O O   . VAL A 1 377  ? 109.184 98.904  79.156  1.00 64.30  ? 336  VAL A O   1 
ATOM   2401 C CB  . VAL A 1 377  ? 107.777 101.718 80.382  1.00 64.30  ? 336  VAL A CB  1 
ATOM   2402 C CG1 . VAL A 1 377  ? 108.380 102.058 79.036  1.00 64.30  ? 336  VAL A CG1 1 
ATOM   2403 C CG2 . VAL A 1 377  ? 106.408 102.355 80.520  1.00 64.30  ? 336  VAL A CG2 1 
ATOM   2404 N N   . ALA A 1 378  ? 109.948 99.579  81.172  1.00 62.46  ? 337  ALA A N   1 
ATOM   2405 C CA  . ALA A 1 378  ? 111.260 98.982  80.935  1.00 62.46  ? 337  ALA A CA  1 
ATOM   2406 C C   . ALA A 1 378  ? 111.155 97.481  80.697  1.00 62.46  ? 337  ALA A C   1 
ATOM   2407 O O   . ALA A 1 378  ? 111.744 96.952  79.745  1.00 62.46  ? 337  ALA A O   1 
ATOM   2408 C CB  . ALA A 1 378  ? 112.188 99.264  82.112  1.00 62.46  ? 337  ALA A CB  1 
ATOM   2409 N N   . ALA A 1 379  ? 110.401 96.780  81.544  1.00 63.26  ? 338  ALA A N   1 
ATOM   2410 C CA  . ALA A 1 379  ? 110.240 95.343  81.388  1.00 63.26  ? 338  ALA A CA  1 
ATOM   2411 C C   . ALA A 1 379  ? 109.512 95.002  80.101  1.00 63.26  ? 338  ALA A C   1 
ATOM   2412 O O   . ALA A 1 379  ? 109.764 93.944  79.519  1.00 63.26  ? 338  ALA A O   1 
ATOM   2413 C CB  . ALA A 1 379  ? 109.497 94.761  82.588  1.00 63.26  ? 338  ALA A CB  1 
ATOM   2414 N N   . ALA A 1 380  ? 108.612 95.872  79.638  1.00 69.32  ? 339  ALA A N   1 
ATOM   2415 C CA  . ALA A 1 380  ? 108.011 95.655  78.327  1.00 69.32  ? 339  ALA A CA  1 
ATOM   2416 C C   . ALA A 1 380  ? 109.082 95.611  77.248  1.00 69.32  ? 339  ALA A C   1 
ATOM   2417 O O   . ALA A 1 380  ? 109.114 94.688  76.425  1.00 69.32  ? 339  ALA A O   1 
ATOM   2418 C CB  . ALA A 1 380  ? 106.989 96.748  78.026  1.00 69.32  ? 339  ALA A CB  1 
ATOM   2419 N N   . LYS A 1 381  ? 109.988 96.592  77.257  1.00 69.04  ? 340  LYS A N   1 
ATOM   2420 C CA  . LYS A 1 381  ? 111.066 96.596  76.264  1.00 69.04  ? 340  LYS A CA  1 
ATOM   2421 C C   . LYS A 1 381  ? 111.934 95.344  76.382  1.00 69.04  ? 340  LYS A C   1 
ATOM   2422 O O   . LYS A 1 381  ? 112.260 94.684  75.379  1.00 69.04  ? 340  LYS A O   1 
ATOM   2423 C CB  . LYS A 1 381  ? 111.925 97.848  76.428  1.00 69.04  ? 340  LYS A CB  1 
ATOM   2424 C CG  . LYS A 1 381  ? 111.308 99.116  75.878  1.00 69.04  ? 340  LYS A CG  1 
ATOM   2425 C CD  . LYS A 1 381  ? 112.371 100.175 75.676  1.00 69.04  ? 340  LYS A CD  1 
ATOM   2426 C CE  . LYS A 1 381  ? 113.126 100.441 76.966  1.00 69.04  ? 340  LYS A CE  1 
ATOM   2427 N NZ  . LYS A 1 381  ? 114.208 101.445 76.784  1.00 69.04  ? 340  LYS A NZ  1 
ATOM   2428 N N   . ILE A 1 382  ? 112.315 95.003  77.612  1.00 65.90  ? 341  ILE A N   1 
ATOM   2429 C CA  . ILE A 1 382  ? 113.221 93.884  77.839  1.00 65.90  ? 341  ILE A CA  1 
ATOM   2430 C C   . ILE A 1 382  ? 112.598 92.573  77.388  1.00 65.90  ? 341  ILE A C   1 
ATOM   2431 O O   . ILE A 1 382  ? 113.260 91.761  76.734  1.00 65.90  ? 341  ILE A O   1 
ATOM   2432 C CB  . ILE A 1 382  ? 113.610 93.827  79.322  1.00 65.90  ? 341  ILE A CB  1 
ATOM   2433 C CG1 . ILE A 1 382  ? 114.379 95.083  79.707  1.00 65.90  ? 341  ILE A CG1 1 
ATOM   2434 C CG2 . ILE A 1 382  ? 114.449 92.601  79.605  1.00 65.90  ? 341  ILE A CG2 1 
ATOM   2435 C CD1 . ILE A 1 382  ? 114.107 95.513  81.116  1.00 65.90  ? 341  ILE A CD1 1 
ATOM   2436 N N   . PHE A 1 383  ? 111.327 92.344  77.718  1.00 67.95  ? 342  PHE A N   1 
ATOM   2437 C CA  . PHE A 1 383  ? 110.664 91.114  77.309  1.00 67.95  ? 342  PHE A CA  1 
ATOM   2438 C C   . PHE A 1 383  ? 110.417 91.093  75.811  1.00 67.95  ? 342  PHE A C   1 
ATOM   2439 O O   . PHE A 1 383  ? 110.404 90.014  75.206  1.00 67.95  ? 342  PHE A O   1 
ATOM   2440 C CB  . PHE A 1 383  ? 109.354 90.946  78.074  1.00 67.95  ? 342  PHE A CB  1 
ATOM   2441 C CG  . PHE A 1 383  ? 109.536 90.743  79.549  1.00 67.95  ? 342  PHE A CG  1 
ATOM   2442 C CD1 . PHE A 1 383  ? 110.778 90.440  80.074  1.00 67.95  ? 342  PHE A CD1 1 
ATOM   2443 C CD2 . PHE A 1 383  ? 108.467 90.868  80.413  1.00 67.95  ? 342  PHE A CD2 1 
ATOM   2444 C CE1 . PHE A 1 383  ? 110.948 90.260  81.429  1.00 67.95  ? 342  PHE A CE1 1 
ATOM   2445 C CE2 . PHE A 1 383  ? 108.632 90.688  81.767  1.00 67.95  ? 342  PHE A CE2 1 
ATOM   2446 C CZ  . PHE A 1 383  ? 109.873 90.384  82.276  1.00 67.95  ? 342  PHE A CZ  1 
ATOM   2447 N N   . ARG A 1 384  ? 110.223 92.262  75.192  1.00 75.06  ? 343  ARG A N   1 
ATOM   2448 C CA  . ARG A 1 384  ? 110.148 92.306  73.738  1.00 75.06  ? 343  ARG A CA  1 
ATOM   2449 C C   . ARG A 1 384  ? 111.422 91.759  73.121  1.00 75.06  ? 343  ARG A C   1 
ATOM   2450 O O   . ARG A 1 384  ? 111.374 90.940  72.196  1.00 75.06  ? 343  ARG A O   1 
ATOM   2451 C CB  . ARG A 1 384  ? 109.900 93.738  73.261  1.00 75.06  ? 343  ARG A CB  1 
ATOM   2452 C CG  . ARG A 1 384  ? 109.638 93.874  71.760  1.00 75.06  ? 343  ARG A CG  1 
ATOM   2453 C CD  . ARG A 1 384  ? 110.918 94.121  70.967  1.00 75.06  ? 343  ARG A CD  1 
ATOM   2454 N NE  . ARG A 1 384  ? 111.627 95.313  71.415  1.00 75.06  ? 343  ARG A NE  1 
ATOM   2455 C CZ  . ARG A 1 384  ? 111.419 96.530  70.933  1.00 75.06  ? 343  ARG A CZ  1 
ATOM   2456 N NH1 . ARG A 1 384  ? 110.546 96.750  69.965  1.00 75.06  ? 343  ARG A NH1 1 
ATOM   2457 N NH2 . ARG A 1 384  ? 112.111 97.551  71.430  1.00 75.06  ? 343  ARG A NH2 1 
ATOM   2458 N N   . ILE A 1 385  ? 112.576 92.203  73.616  1.00 72.57  ? 344  ILE A N   1 
ATOM   2459 C CA  . ILE A 1 385  ? 113.829 91.723  73.036  1.00 72.57  ? 344  ILE A CA  1 
ATOM   2460 C C   . ILE A 1 385  ? 114.071 90.258  73.396  1.00 72.57  ? 344  ILE A C   1 
ATOM   2461 O O   . ILE A 1 385  ? 114.600 89.488  72.587  1.00 72.57  ? 344  ILE A O   1 
ATOM   2462 C CB  . ILE A 1 385  ? 115.002 92.623  73.459  1.00 72.57  ? 344  ILE A CB  1 
ATOM   2463 C CG1 . ILE A 1 385  ? 114.788 94.036  72.917  1.00 72.57  ? 344  ILE A CG1 1 
ATOM   2464 C CG2 . ILE A 1 385  ? 116.308 92.067  72.923  1.00 72.57  ? 344  ILE A CG2 1 
ATOM   2465 C CD1 . ILE A 1 385  ? 115.736 95.065  73.480  1.00 72.57  ? 344  ILE A CD1 1 
ATOM   2466 N N   . ILE A 1 386  ? 113.687 89.848  74.607  1.00 70.36  ? 345  ILE A N   1 
ATOM   2467 C CA  . ILE A 1 386  ? 113.930 88.472  75.042  1.00 70.36  ? 345  ILE A CA  1 
ATOM   2468 C C   . ILE A 1 386  ? 113.116 87.487  74.212  1.00 70.36  ? 345  ILE A C   1 
ATOM   2469 O O   . ILE A 1 386  ? 113.637 86.473  73.735  1.00 70.36  ? 345  ILE A O   1 
ATOM   2470 C CB  . ILE A 1 386  ? 113.622 88.318  76.542  1.00 70.36  ? 345  ILE A CB  1 
ATOM   2471 C CG1 . ILE A 1 386  ? 114.739 88.914  77.392  1.00 70.36  ? 345  ILE A CG1 1 
ATOM   2472 C CG2 . ILE A 1 386  ? 113.424 86.856  76.898  1.00 70.36  ? 345  ILE A CG2 1 
ATOM   2473 C CD1 . ILE A 1 386  ? 114.538 88.713  78.874  1.00 70.36  ? 345  ILE A CD1 1 
ATOM   2474 N N   . ASP A 1 387  ? 111.825 87.767  74.025  1.00 77.06  ? 346  ASP A N   1 
ATOM   2475 C CA  . ASP A 1 387  ? 110.926 86.788  73.426  1.00 77.06  ? 346  ASP A CA  1 
ATOM   2476 C C   . ASP A 1 387  ? 111.054 86.696  71.913  1.00 77.06  ? 346  ASP A C   1 
ATOM   2477 O O   . ASP A 1 387  ? 110.445 85.801  71.317  1.00 77.06  ? 346  ASP A O   1 
ATOM   2478 C CB  . ASP A 1 387  ? 109.479 87.109  73.794  1.00 77.06  ? 346  ASP A CB  1 
ATOM   2479 C CG  . ASP A 1 387  ? 109.176 86.836  75.251  1.00 77.06  ? 346  ASP A CG  1 
ATOM   2480 O OD1 . ASP A 1 387  ? 109.491 85.726  75.728  1.00 77.06  ? 346  ASP A OD1 1 
ATOM   2481 O OD2 . ASP A 1 387  ? 108.619 87.730  75.922  1.00 77.06  ? 346  ASP A OD2 1 
ATOM   2482 N N   . HIS A 1 388  ? 111.811 87.588  71.279  1.00 85.40  ? 347  HIS A N   1 
ATOM   2483 C CA  . HIS A 1 388  ? 111.964 87.539  69.832  1.00 85.40  ? 347  HIS A CA  1 
ATOM   2484 C C   . HIS A 1 388  ? 112.648 86.245  69.410  1.00 85.40  ? 347  HIS A C   1 
ATOM   2485 O O   . HIS A 1 388  ? 113.577 85.771  70.069  1.00 85.40  ? 347  HIS A O   1 
ATOM   2486 C CB  . HIS A 1 388  ? 112.767 88.743  69.344  1.00 85.40  ? 347  HIS A CB  1 
ATOM   2487 C CG  . HIS A 1 388  ? 112.594 89.035  67.886  1.00 85.40  ? 347  HIS A CG  1 
ATOM   2488 N ND1 . HIS A 1 388  ? 112.991 88.159  66.900  1.00 85.40  ? 347  HIS A ND1 1 
ATOM   2489 C CD2 . HIS A 1 388  ? 112.071 90.108  67.249  1.00 85.40  ? 347  HIS A CD2 1 
ATOM   2490 C CE1 . HIS A 1 388  ? 112.717 88.678  65.717  1.00 85.40  ? 347  HIS A CE1 1 
ATOM   2491 N NE2 . HIS A 1 388  ? 112.158 89.860  65.900  1.00 85.40  ? 347  HIS A NE2 1 
ATOM   2492 N N   . LYS A 1 389  ? 112.180 85.673  68.303  1.00 92.03  ? 348  LYS A N   1 
ATOM   2493 C CA  . LYS A 1 389  ? 112.720 84.425  67.791  1.00 92.03  ? 348  LYS A CA  1 
ATOM   2494 C C   . LYS A 1 389  ? 113.523 84.679  66.527  1.00 92.03  ? 348  LYS A C   1 
ATOM   2495 O O   . LYS A 1 389  ? 113.040 85.375  65.624  1.00 92.03  ? 348  LYS A O   1 
ATOM   2496 C CB  . LYS A 1 389  ? 111.595 83.427  67.503  1.00 92.03  ? 348  LYS A CB  1 
ATOM   2497 C CG  . LYS A 1 389  ? 110.909 82.903  68.750  1.00 92.03  ? 348  LYS A CG  1 
ATOM   2498 C CD  . LYS A 1 389  ? 111.922 82.343  69.735  1.00 92.03  ? 348  LYS A CD  1 
ATOM   2499 C CE  . LYS A 1 389  ? 111.272 81.995  71.065  1.00 92.03  ? 348  LYS A CE  1 
ATOM   2500 N NZ  . LYS A 1 389  ? 110.791 83.203  71.788  1.00 92.03  ? 348  LYS A NZ  1 
ATOM   2501 N N   . PRO A 1 390  ? 114.741 84.148  66.430  1.00 98.09  ? 349  PRO A N   1 
ATOM   2502 C CA  . PRO A 1 390  ? 115.548 84.368  65.224  1.00 98.09  ? 349  PRO A CA  1 
ATOM   2503 C C   . PRO A 1 390  ? 114.901 83.744  63.996  1.00 98.09  ? 349  PRO A C   1 
ATOM   2504 O O   . PRO A 1 390  ? 114.251 82.699  64.076  1.00 98.09  ? 349  PRO A O   1 
ATOM   2505 C CB  . PRO A 1 390  ? 116.883 83.692  65.561  1.00 98.09  ? 349  PRO A CB  1 
ATOM   2506 C CG  . PRO A 1 390  ? 116.894 83.577  67.052  1.00 98.09  ? 349  PRO A CG  1 
ATOM   2507 C CD  . PRO A 1 390  ? 115.470 83.382  67.452  1.00 98.09  ? 349  PRO A CD  1 
ATOM   2508 N N   . THR A 1 391  ? 115.091 84.400  62.850  1.00 107.15 ? 350  THR A N   1 
ATOM   2509 C CA  . THR A 1 391  ? 114.499 83.917  61.608  1.00 107.15 ? 350  THR A CA  1 
ATOM   2510 C C   . THR A 1 391  ? 115.416 82.934  60.892  1.00 107.15 ? 350  THR A C   1 
ATOM   2511 O O   . THR A 1 391  ? 114.951 81.912  60.378  1.00 107.15 ? 350  THR A O   1 
ATOM   2512 C CB  . THR A 1 391  ? 114.170 85.092  60.689  1.00 107.15 ? 350  THR A CB  1 
ATOM   2513 O OG1 . THR A 1 391  ? 115.376 85.789  60.355  1.00 107.15 ? 350  THR A OG1 1 
ATOM   2514 C CG2 . THR A 1 391  ? 113.214 86.051  61.376  1.00 107.15 ? 350  THR A CG2 1 
ATOM   2515 N N   . ILE A 1 392  ? 116.716 83.226  60.848  1.00 112.42 ? 351  ILE A N   1 
ATOM   2516 C CA  . ILE A 1 392  ? 117.661 82.338  60.182  1.00 112.42 ? 351  ILE A CA  1 
ATOM   2517 C C   . ILE A 1 392  ? 117.844 81.083  61.022  1.00 112.42 ? 351  ILE A C   1 
ATOM   2518 O O   . ILE A 1 392  ? 118.184 81.154  62.210  1.00 112.42 ? 351  ILE A O   1 
ATOM   2519 C CB  . ILE A 1 392  ? 118.998 83.054  59.944  1.00 112.42 ? 351  ILE A CB  1 
ATOM   2520 C CG1 . ILE A 1 392  ? 118.816 84.202  58.949  1.00 112.42 ? 351  ILE A CG1 1 
ATOM   2521 C CG2 . ILE A 1 392  ? 120.044 82.071  59.446  1.00 112.42 ? 351  ILE A CG2 1 
ATOM   2522 C CD1 . ILE A 1 392  ? 119.912 85.238  59.007  1.00 112.42 ? 351  ILE A CD1 1 
ATOM   2523 N N   . GLU A 1 393  ? 117.620 79.927  60.405  1.00 123.08 ? 352  GLU A N   1 
ATOM   2524 C CA  . GLU A 1 393  ? 117.652 78.669  61.137  1.00 123.08 ? 352  GLU A CA  1 
ATOM   2525 C C   . GLU A 1 393  ? 119.059 78.360  61.632  1.00 123.08 ? 352  GLU A C   1 
ATOM   2526 O O   . GLU A 1 393  ? 120.048 78.555  60.920  1.00 123.08 ? 352  GLU A O   1 
ATOM   2527 C CB  . GLU A 1 393  ? 117.137 77.531  60.255  1.00 123.08 ? 352  GLU A CB  1 
ATOM   2528 C CG  . GLU A 1 393  ? 117.893 77.347  58.949  1.00 123.08 ? 352  GLU A CG  1 
ATOM   2529 C CD  . GLU A 1 393  ? 117.331 78.191  57.821  1.00 123.08 ? 352  GLU A CD  1 
ATOM   2530 O OE1 . GLU A 1 393  ? 116.639 79.189  58.107  1.00 123.08 ? 352  GLU A OE1 1 
ATOM   2531 O OE2 . GLU A 1 393  ? 117.582 77.854  56.644  1.00 123.08 ? 352  GLU A OE2 1 
ATOM   2532 N N   . ARG A 1 394  ? 119.141 77.882  62.870  1.00 124.53 ? 353  ARG A N   1 
ATOM   2533 C CA  . ARG A 1 394  ? 120.397 77.491  63.486  1.00 124.53 ? 353  ARG A CA  1 
ATOM   2534 C C   . ARG A 1 394  ? 120.214 76.144  64.168  1.00 124.53 ? 353  ARG A C   1 
ATOM   2535 O O   . ARG A 1 394  ? 119.096 75.749  64.512  1.00 124.53 ? 353  ARG A O   1 
ATOM   2536 C CB  . ARG A 1 394  ? 120.886 78.540  64.491  1.00 124.53 ? 353  ARG A CB  1 
ATOM   2537 C CG  . ARG A 1 394  ? 119.895 78.848  65.597  1.00 124.53 ? 353  ARG A CG  1 
ATOM   2538 C CD  . ARG A 1 394  ? 120.323 80.068  66.393  1.00 124.53 ? 353  ARG A CD  1 
ATOM   2539 N NE  . ARG A 1 394  ? 120.398 81.263  65.559  1.00 124.53 ? 353  ARG A NE  1 
ATOM   2540 C CZ  . ARG A 1 394  ? 121.528 81.839  65.177  1.00 124.53 ? 353  ARG A CZ  1 
ATOM   2541 N NH1 . ARG A 1 394  ? 122.705 81.357  65.539  1.00 124.53 ? 353  ARG A NH1 1 
ATOM   2542 N NH2 . ARG A 1 394  ? 121.477 82.926  64.414  1.00 124.53 ? 353  ARG A NH2 1 
ATOM   2543 N N   . ASN A 1 395  ? 121.333 75.443  64.361  1.00 142.19 ? 354  ASN A N   1 
ATOM   2544 C CA  . ASN A 1 395  ? 121.319 74.054  64.821  1.00 142.19 ? 354  ASN A CA  1 
ATOM   2545 C C   . ASN A 1 395  ? 120.457 73.195  63.899  1.00 142.19 ? 354  ASN A C   1 
ATOM   2546 O O   . ASN A 1 395  ? 119.675 72.355  64.348  1.00 142.19 ? 354  ASN A O   1 
ATOM   2547 C CB  . ASN A 1 395  ? 120.847 73.947  66.273  1.00 142.19 ? 354  ASN A CB  1 
ATOM   2548 C CG  . ASN A 1 395  ? 121.427 72.742  66.988  1.00 142.19 ? 354  ASN A CG  1 
ATOM   2549 O OD1 . ASN A 1 395  ? 121.242 71.602  66.561  1.00 142.19 ? 354  ASN A OD1 1 
ATOM   2550 N ND2 . ASN A 1 395  ? 122.135 72.989  68.083  1.00 142.19 ? 354  ASN A ND2 1 
ATOM   2551 N N   . SER A 1 396  ? 120.597 73.421  62.596  1.00 148.71 ? 355  SER A N   1 
ATOM   2552 C CA  . SER A 1 396  ? 119.811 72.703  61.609  1.00 148.71 ? 355  SER A CA  1 
ATOM   2553 C C   . SER A 1 396  ? 120.212 71.230  61.572  1.00 148.71 ? 355  SER A C   1 
ATOM   2554 O O   . SER A 1 396  ? 121.211 70.809  62.161  1.00 148.71 ? 355  SER A O   1 
ATOM   2555 C CB  . SER A 1 396  ? 119.983 73.337  60.229  1.00 148.71 ? 355  SER A CB  1 
ATOM   2556 O OG  . SER A 1 396  ? 119.381 72.541  59.222  1.00 148.71 ? 355  SER A OG  1 
ATOM   2557 N N   . GLU A 1 397  ? 119.403 70.438  60.873  1.00 150.09 ? 356  GLU A N   1 
ATOM   2558 C CA  . GLU A 1 397  ? 119.662 69.017  60.700  1.00 150.09 ? 356  GLU A CA  1 
ATOM   2559 C C   . GLU A 1 397  ? 120.067 68.659  59.279  1.00 150.09 ? 356  GLU A C   1 
ATOM   2560 O O   . GLU A 1 397  ? 120.219 67.472  58.971  1.00 150.09 ? 356  GLU A O   1 
ATOM   2561 C CB  . GLU A 1 397  ? 118.431 68.201  61.108  1.00 150.09 ? 356  GLU A CB  1 
ATOM   2562 C CG  . GLU A 1 397  ? 117.953 68.470  62.524  1.00 150.09 ? 356  GLU A CG  1 
ATOM   2563 C CD  . GLU A 1 397  ? 119.065 68.347  63.546  1.00 150.09 ? 356  GLU A CD  1 
ATOM   2564 O OE1 . GLU A 1 397  ? 119.738 67.295  63.572  1.00 150.09 ? 356  GLU A OE1 1 
ATOM   2565 O OE2 . GLU A 1 397  ? 119.266 69.303  64.326  1.00 150.09 ? 356  GLU A OE2 1 
ATOM   2566 N N   . SER A 1 398  ? 120.247 69.648  58.407  1.00 154.06 ? 357  SER A N   1 
ATOM   2567 C CA  . SER A 1 398  ? 120.600 69.399  57.017  1.00 154.06 ? 357  SER A CA  1 
ATOM   2568 C C   . SER A 1 398  ? 122.102 69.308  56.785  1.00 154.06 ? 357  SER A C   1 
ATOM   2569 O O   . SER A 1 398  ? 122.518 68.952  55.678  1.00 154.06 ? 357  SER A O   1 
ATOM   2570 C CB  . SER A 1 398  ? 120.018 70.497  56.120  1.00 154.06 ? 357  SER A CB  1 
ATOM   2571 O OG  . SER A 1 398  ? 120.568 71.762  56.445  1.00 154.06 ? 357  SER A OG  1 
ATOM   2572 N N   . GLY A 1 399  ? 122.918 69.615  57.791  1.00 153.08 ? 358  GLY A N   1 
ATOM   2573 C CA  . GLY A 1 399  ? 124.357 69.624  57.625  1.00 153.08 ? 358  GLY A CA  1 
ATOM   2574 C C   . GLY A 1 399  ? 124.942 68.286  57.228  1.00 153.08 ? 358  GLY A C   1 
ATOM   2575 O O   . GLY A 1 399  ? 124.797 67.294  57.947  1.00 153.08 ? 358  GLY A O   1 
ATOM   2576 N N   . VAL A 1 400  ? 125.612 68.254  56.075  1.00 155.84 ? 359  VAL A N   1 
ATOM   2577 C CA  . VAL A 1 400  ? 126.229 67.022  55.603  1.00 155.84 ? 359  VAL A CA  1 
ATOM   2578 C C   . VAL A 1 400  ? 127.439 66.646  56.448  1.00 155.84 ? 359  VAL A C   1 
ATOM   2579 O O   . VAL A 1 400  ? 127.819 65.470  56.494  1.00 155.84 ? 359  VAL A O   1 
ATOM   2580 C CB  . VAL A 1 400  ? 126.605 67.163  54.116  1.00 155.84 ? 359  VAL A CB  1 
ATOM   2581 C CG1 . VAL A 1 400  ? 127.057 65.830  53.536  1.00 155.84 ? 359  VAL A CG1 1 
ATOM   2582 C CG2 . VAL A 1 400  ? 125.429 67.714  53.327  1.00 155.84 ? 359  VAL A CG2 1 
ATOM   2583 N N   . GLU A 1 401  ? 128.042 67.617  57.140  1.00 152.69 ? 360  GLU A N   1 
ATOM   2584 C CA  . GLU A 1 401  ? 129.255 67.396  57.929  1.00 152.69 ? 360  GLU A CA  1 
ATOM   2585 C C   . GLU A 1 401  ? 130.371 66.817  57.064  1.00 152.69 ? 360  GLU A C   1 
ATOM   2586 O O   . GLU A 1 401  ? 131.132 65.947  57.493  1.00 152.69 ? 360  GLU A O   1 
ATOM   2587 C CB  . GLU A 1 401  ? 128.979 66.503  59.141  1.00 152.69 ? 360  GLU A CB  1 
ATOM   2588 C CG  . GLU A 1 401  ? 127.710 66.862  59.897  1.00 152.69 ? 360  GLU A CG  1 
ATOM   2589 C CD  . GLU A 1 401  ? 127.905 68.033  60.837  1.00 152.69 ? 360  GLU A CD  1 
ATOM   2590 O OE1 . GLU A 1 401  ? 129.051 68.506  60.973  1.00 152.69 ? 360  GLU A OE1 1 
ATOM   2591 O OE2 . GLU A 1 401  ? 126.909 68.482  61.444  1.00 152.69 ? 360  GLU A OE2 1 
ATOM   2592 N N   . LEU A 1 402  ? 130.461 67.308  55.832  1.00 160.28 ? 361  LEU A N   1 
ATOM   2593 C CA  . LEU A 1 402  ? 131.476 66.844  54.899  1.00 160.28 ? 361  LEU A CA  1 
ATOM   2594 C C   . LEU A 1 402  ? 132.874 67.174  55.409  1.00 160.28 ? 361  LEU A C   1 
ATOM   2595 O O   . LEU A 1 402  ? 133.102 68.229  56.008  1.00 160.28 ? 361  LEU A O   1 
ATOM   2596 C CB  . LEU A 1 402  ? 131.227 67.460  53.520  1.00 160.28 ? 361  LEU A CB  1 
ATOM   2597 C CG  . LEU A 1 402  ? 131.261 68.986  53.341  1.00 160.28 ? 361  LEU A CG  1 
ATOM   2598 C CD1 . LEU A 1 402  ? 132.664 69.547  53.154  1.00 160.28 ? 361  LEU A CD1 1 
ATOM   2599 C CD2 . LEU A 1 402  ? 130.358 69.403  52.188  1.00 160.28 ? 361  LEU A CD2 1 
ATOM   2600 N N   . ASP A 1 403  ? 133.808 66.252  55.184  1.00 166.57 ? 362  ASP A N   1 
ATOM   2601 C CA  . ASP A 1 403  ? 135.181 66.420  55.640  1.00 166.57 ? 362  ASP A CA  1 
ATOM   2602 C C   . ASP A 1 403  ? 136.078 67.102  54.617  1.00 166.57 ? 362  ASP A C   1 
ATOM   2603 O O   . ASP A 1 403  ? 137.222 67.430  54.945  1.00 166.57 ? 362  ASP A O   1 
ATOM   2604 C CB  . ASP A 1 403  ? 135.780 65.062  56.020  1.00 166.57 ? 362  ASP A CB  1 
ATOM   2605 C CG  . ASP A 1 403  ? 135.146 64.474  57.265  1.00 166.57 ? 362  ASP A CG  1 
ATOM   2606 O OD1 . ASP A 1 403  ? 134.691 65.255  58.127  1.00 166.57 ? 362  ASP A OD1 1 
ATOM   2607 O OD2 . ASP A 1 403  ? 135.102 63.231  57.384  1.00 166.57 ? 362  ASP A OD2 1 
ATOM   2608 N N   . SER A 1 404  ? 135.593 67.328  53.397  1.00 167.62 ? 363  SER A N   1 
ATOM   2609 C CA  . SER A 1 404  ? 136.375 68.017  52.370  1.00 167.62 ? 363  SER A CA  1 
ATOM   2610 C C   . SER A 1 404  ? 136.342 69.508  52.677  1.00 167.62 ? 363  SER A C   1 
ATOM   2611 O O   . SER A 1 404  ? 135.566 70.269  52.100  1.00 167.62 ? 363  SER A O   1 
ATOM   2612 C CB  . SER A 1 404  ? 135.829 67.715  50.980  1.00 167.62 ? 363  SER A CB  1 
ATOM   2613 O OG  . SER A 1 404  ? 134.455 68.048  50.887  1.00 167.62 ? 363  SER A OG  1 
ATOM   2614 N N   . VAL A 1 405  ? 137.215 69.928  53.596  1.00 164.09 ? 364  VAL A N   1 
ATOM   2615 C CA  . VAL A 1 405  ? 137.199 71.307  54.076  1.00 164.09 ? 364  VAL A CA  1 
ATOM   2616 C C   . VAL A 1 405  ? 137.503 72.288  52.951  1.00 164.09 ? 364  VAL A C   1 
ATOM   2617 O O   . VAL A 1 405  ? 137.102 73.456  53.014  1.00 164.09 ? 364  VAL A O   1 
ATOM   2618 C CB  . VAL A 1 405  ? 138.188 71.472  55.247  1.00 164.09 ? 364  VAL A CB  1 
ATOM   2619 C CG1 . VAL A 1 405  ? 137.689 70.717  56.470  1.00 164.09 ? 364  VAL A CG1 1 
ATOM   2620 C CG2 . VAL A 1 405  ? 139.572 70.988  54.846  1.00 164.09 ? 364  VAL A CG2 1 
ATOM   2621 N N   . THR A 1 406  ? 138.209 71.842  51.916  1.00 165.79 ? 365  THR A N   1 
ATOM   2622 C CA  . THR A 1 406  ? 138.561 72.729  50.815  1.00 165.79 ? 365  THR A CA  1 
ATOM   2623 C C   . THR A 1 406  ? 137.315 73.135  50.039  1.00 165.79 ? 365  THR A C   1 
ATOM   2624 O O   . THR A 1 406  ? 136.520 72.286  49.629  1.00 165.79 ? 365  THR A O   1 
ATOM   2625 C CB  . THR A 1 406  ? 139.560 72.046  49.883  1.00 165.79 ? 365  THR A CB  1 
ATOM   2626 O OG1 . THR A 1 406  ? 138.912 70.972  49.192  1.00 165.79 ? 365  THR A OG1 1 
ATOM   2627 C CG2 . THR A 1 406  ? 140.735 71.495  50.676  1.00 165.79 ? 365  THR A CG2 1 
ATOM   2628 N N   . GLY A 1 407  ? 137.150 74.439  49.836  1.00 165.95 ? 366  GLY A N   1 
ATOM   2629 C CA  . GLY A 1 407  ? 136.042 74.947  49.053  1.00 165.95 ? 366  GLY A CA  1 
ATOM   2630 C C   . GLY A 1 407  ? 136.408 75.094  47.593  1.00 165.95 ? 366  GLY A C   1 
ATOM   2631 O O   . GLY A 1 407  ? 137.155 76.006  47.227  1.00 165.95 ? 366  GLY A O   1 
ATOM   2632 N N   . LEU A 1 408  ? 135.895 74.194  46.751  1.00 167.41 ? 367  LEU A N   1 
ATOM   2633 C CA  . LEU A 1 408  ? 136.271 74.191  45.340  1.00 167.41 ? 367  LEU A CA  1 
ATOM   2634 C C   . LEU A 1 408  ? 135.925 75.515  44.672  1.00 167.41 ? 367  LEU A C   1 
ATOM   2635 O O   . LEU A 1 408  ? 136.814 76.252  44.231  1.00 167.41 ? 367  LEU A O   1 
ATOM   2636 C CB  . LEU A 1 408  ? 135.589 73.031  44.613  1.00 167.41 ? 367  LEU A CB  1 
ATOM   2637 C CG  . LEU A 1 408  ? 136.224 71.636  44.644  1.00 167.41 ? 367  LEU A CG  1 
ATOM   2638 C CD1 . LEU A 1 408  ? 137.571 71.649  43.940  1.00 167.41 ? 367  LEU A CD1 1 
ATOM   2639 C CD2 . LEU A 1 408  ? 136.358 71.086  46.059  1.00 167.41 ? 367  LEU A CD2 1 
ATOM   2640 N N   . VAL A 1 409  ? 134.635 75.840  44.602  1.00 168.72 ? 368  VAL A N   1 
ATOM   2641 C CA  . VAL A 1 409  ? 134.172 77.057  43.945  1.00 168.72 ? 368  VAL A CA  1 
ATOM   2642 C C   . VAL A 1 409  ? 132.733 77.287  44.377  1.00 168.72 ? 368  VAL A C   1 
ATOM   2643 O O   . VAL A 1 409  ? 131.979 76.336  44.601  1.00 168.72 ? 368  VAL A O   1 
ATOM   2644 C CB  . VAL A 1 409  ? 134.322 76.951  42.404  1.00 168.72 ? 368  VAL A CB  1 
ATOM   2645 C CG1 . VAL A 1 409  ? 133.402 75.877  41.832  1.00 168.72 ? 368  VAL A CG1 1 
ATOM   2646 C CG2 . VAL A 1 409  ? 134.087 78.302  41.740  1.00 168.72 ? 368  VAL A CG2 1 
ATOM   2647 N N   . GLU A 1 410  ? 132.353 78.556  44.513  1.00 165.89 ? 369  GLU A N   1 
ATOM   2648 C CA  . GLU A 1 410  ? 131.057 78.883  45.092  1.00 165.89 ? 369  GLU A CA  1 
ATOM   2649 C C   . GLU A 1 410  ? 130.645 80.289  44.682  1.00 165.89 ? 369  GLU A C   1 
ATOM   2650 O O   . GLU A 1 410  ? 131.306 80.947  43.874  1.00 165.89 ? 369  GLU A O   1 
ATOM   2651 C CB  . GLU A 1 410  ? 131.091 78.755  46.617  1.00 165.89 ? 369  GLU A CB  1 
ATOM   2652 C CG  . GLU A 1 410  ? 132.043 79.719  47.303  1.00 165.89 ? 369  GLU A CG  1 
ATOM   2653 C CD  . GLU A 1 410  ? 133.337 79.057  47.729  1.00 165.89 ? 369  GLU A CD  1 
ATOM   2654 O OE1 . GLU A 1 410  ? 133.626 77.941  47.246  1.00 165.89 ? 369  GLU A OE1 1 
ATOM   2655 O OE2 . GLU A 1 410  ? 134.068 79.651  48.549  1.00 165.89 ? 369  GLU A OE2 1 
ATOM   2656 N N   . LEU A 1 411  ? 129.527 80.737  45.260  1.00 165.67 ? 370  LEU A N   1 
ATOM   2657 C CA  . LEU A 1 411  ? 129.008 82.098  45.117  1.00 165.67 ? 370  LEU A CA  1 
ATOM   2658 C C   . LEU A 1 411  ? 128.707 82.433  43.651  1.00 165.67 ? 370  LEU A C   1 
ATOM   2659 O O   . LEU A 1 411  ? 129.327 83.299  43.031  1.00 165.67 ? 370  LEU A O   1 
ATOM   2660 C CB  . LEU A 1 411  ? 129.980 83.111  45.733  1.00 165.67 ? 370  LEU A CB  1 
ATOM   2661 C CG  . LEU A 1 411  ? 129.373 84.460  46.114  1.00 165.67 ? 370  LEU A CG  1 
ATOM   2662 C CD1 . LEU A 1 411  ? 128.507 84.321  47.352  1.00 165.67 ? 370  LEU A CD1 1 
ATOM   2663 C CD2 . LEU A 1 411  ? 130.466 85.479  46.346  1.00 165.67 ? 370  LEU A CD2 1 
ATOM   2664 N N   . LYS A 1 412  ? 127.726 81.712  43.111  1.00 168.89 ? 371  LYS A N   1 
ATOM   2665 C CA  . LYS A 1 412  ? 127.228 81.941  41.762  1.00 168.89 ? 371  LYS A CA  1 
ATOM   2666 C C   . LYS A 1 412  ? 125.959 82.778  41.810  1.00 168.89 ? 371  LYS A C   1 
ATOM   2667 O O   . LYS A 1 412  ? 125.093 82.558  42.662  1.00 168.89 ? 371  LYS A O   1 
ATOM   2668 C CB  . LYS A 1 412  ? 126.908 80.631  41.030  1.00 168.89 ? 371  LYS A CB  1 
ATOM   2669 C CG  . LYS A 1 412  ? 128.094 79.903  40.435  1.00 168.89 ? 371  LYS A CG  1 
ATOM   2670 C CD  . LYS A 1 412  ? 128.930 79.245  41.503  1.00 168.89 ? 371  LYS A CD  1 
ATOM   2671 C CE  . LYS A 1 412  ? 130.050 78.442  40.888  1.00 168.89 ? 371  LYS A CE  1 
ATOM   2672 N NZ  . LYS A 1 412  ? 130.923 77.902  41.949  1.00 168.89 ? 371  LYS A NZ  1 
ATOM   2673 N N   . ASN A 1 413  ? 125.861 83.742  40.892  1.00 168.80 ? 372  ASN A N   1 
ATOM   2674 C CA  . ASN A 1 413  ? 124.609 84.451  40.614  1.00 168.80 ? 372  ASN A CA  1 
ATOM   2675 C C   . ASN A 1 413  ? 123.983 85.024  41.882  1.00 168.80 ? 372  ASN A C   1 
ATOM   2676 O O   . ASN A 1 413  ? 122.769 84.958  42.084  1.00 168.80 ? 372  ASN A O   1 
ATOM   2677 C CB  . ASN A 1 413  ? 123.621 83.536  39.890  1.00 168.80 ? 372  ASN A CB  1 
ATOM   2678 C CG  . ASN A 1 413  ? 124.263 82.769  38.752  1.00 168.80 ? 372  ASN A CG  1 
ATOM   2679 O OD1 . ASN A 1 413  ? 124.749 83.358  37.787  1.00 168.80 ? 372  ASN A OD1 1 
ATOM   2680 N ND2 . ASN A 1 413  ? 124.271 81.445  38.860  1.00 168.80 ? 372  ASN A ND2 1 
ATOM   2681 N N   . VAL A 1 414  ? 124.816 85.584  42.749  1.00 165.33 ? 373  VAL A N   1 
ATOM   2682 C CA  . VAL A 1 414  ? 124.330 86.153  44.000  1.00 165.33 ? 373  VAL A CA  1 
ATOM   2683 C C   . VAL A 1 414  ? 123.527 87.412  43.700  1.00 165.33 ? 373  VAL A C   1 
ATOM   2684 O O   . VAL A 1 414  ? 123.951 88.272  42.919  1.00 165.33 ? 373  VAL A O   1 
ATOM   2685 C CB  . VAL A 1 414  ? 125.502 86.429  44.958  1.00 165.33 ? 373  VAL A CB  1 
ATOM   2686 C CG1 . VAL A 1 414  ? 126.556 87.285  44.282  1.00 165.33 ? 373  VAL A CG1 1 
ATOM   2687 C CG2 . VAL A 1 414  ? 125.005 87.094  46.229  1.00 165.33 ? 373  VAL A CG2 1 
ATOM   2688 N N   . ASP A 1 415  ? 122.350 87.513  44.309  1.00 160.36 ? 374  ASP A N   1 
ATOM   2689 C CA  . ASP A 1 415  ? 121.408 88.596  44.048  1.00 160.36 ? 374  ASP A CA  1 
ATOM   2690 C C   . ASP A 1 415  ? 120.998 89.277  45.342  1.00 160.36 ? 374  ASP A C   1 
ATOM   2691 O O   . ASP A 1 415  ? 119.864 89.740  45.490  1.00 160.36 ? 374  ASP A O   1 
ATOM   2692 C CB  . ASP A 1 415  ? 120.182 88.080  43.300  1.00 160.36 ? 374  ASP A CB  1 
ATOM   2693 C CG  . ASP A 1 415  ? 119.652 86.784  43.878  1.00 160.36 ? 374  ASP A CG  1 
ATOM   2694 O OD1 . ASP A 1 415  ? 120.184 86.323  44.909  1.00 160.36 ? 374  ASP A OD1 1 
ATOM   2695 O OD2 . ASP A 1 415  ? 118.705 86.221  43.296  1.00 160.36 ? 374  ASP A OD2 1 
ATOM   2696 N N   . PHE A 1 416  ? 121.919 89.355  46.297  1.00 150.82 ? 375  PHE A N   1 
ATOM   2697 C CA  . PHE A 1 416  ? 121.585 89.869  47.618  1.00 150.82 ? 375  PHE A CA  1 
ATOM   2698 C C   . PHE A 1 416  ? 121.272 91.359  47.572  1.00 150.82 ? 375  PHE A C   1 
ATOM   2699 O O   . PHE A 1 416  ? 121.976 92.142  46.930  1.00 150.82 ? 375  PHE A O   1 
ATOM   2700 C CB  . PHE A 1 416  ? 122.733 89.610  48.590  1.00 150.82 ? 375  PHE A CB  1 
ATOM   2701 C CG  . PHE A 1 416  ? 122.576 90.307  49.909  1.00 150.82 ? 375  PHE A CG  1 
ATOM   2702 C CD1 . PHE A 1 416  ? 121.673 89.844  50.848  1.00 150.82 ? 375  PHE A CD1 1 
ATOM   2703 C CD2 . PHE A 1 416  ? 123.333 91.425  50.210  1.00 150.82 ? 375  PHE A CD2 1 
ATOM   2704 C CE1 . PHE A 1 416  ? 121.528 90.482  52.061  1.00 150.82 ? 375  PHE A CE1 1 
ATOM   2705 C CE2 . PHE A 1 416  ? 123.193 92.068  51.422  1.00 150.82 ? 375  PHE A CE2 1 
ATOM   2706 C CZ  . PHE A 1 416  ? 122.289 91.596  52.349  1.00 150.82 ? 375  PHE A CZ  1 
ATOM   2707 N N   . SER A 1 417  ? 120.204 91.742  48.265  1.00 153.68 ? 376  SER A N   1 
ATOM   2708 C CA  . SER A 1 417  ? 119.836 93.133  48.470  1.00 153.68 ? 376  SER A CA  1 
ATOM   2709 C C   . SER A 1 417  ? 119.844 93.428  49.963  1.00 153.68 ? 376  SER A C   1 
ATOM   2710 O O   . SER A 1 417  ? 119.488 92.574  50.778  1.00 153.68 ? 376  SER A O   1 
ATOM   2711 C CB  . SER A 1 417  ? 118.455 93.441  47.883  1.00 153.68 ? 376  SER A CB  1 
ATOM   2712 O OG  . SER A 1 417  ? 117.429 92.871  48.676  1.00 153.68 ? 376  SER A OG  1 
ATOM   2713 N N   . TYR A 1 418  ? 120.258 94.639  50.315  1.00 150.48 ? 377  TYR A N   1 
ATOM   2714 C CA  . TYR A 1 418  ? 120.465 94.958  51.718  1.00 150.48 ? 377  TYR A CA  1 
ATOM   2715 C C   . TYR A 1 418  ? 119.132 94.902  52.463  1.00 150.48 ? 377  TYR A C   1 
ATOM   2716 O O   . TYR A 1 418  ? 118.113 95.378  51.949  1.00 150.48 ? 377  TYR A O   1 
ATOM   2717 C CB  . TYR A 1 418  ? 121.109 96.337  51.866  1.00 150.48 ? 377  TYR A CB  1 
ATOM   2718 C CG  . TYR A 1 418  ? 122.057 96.432  53.037  1.00 150.48 ? 377  TYR A CG  1 
ATOM   2719 C CD1 . TYR A 1 418  ? 123.353 95.942  52.939  1.00 150.48 ? 377  TYR A CD1 1 
ATOM   2720 C CD2 . TYR A 1 418  ? 121.665 97.011  54.235  1.00 150.48 ? 377  TYR A CD2 1 
ATOM   2721 C CE1 . TYR A 1 418  ? 124.230 96.021  54.000  1.00 150.48 ? 377  TYR A CE1 1 
ATOM   2722 C CE2 . TYR A 1 418  ? 122.538 97.095  55.304  1.00 150.48 ? 377  TYR A CE2 1 
ATOM   2723 C CZ  . TYR A 1 418  ? 123.819 96.598  55.179  1.00 150.48 ? 377  TYR A CZ  1 
ATOM   2724 O OH  . TYR A 1 418  ? 124.694 96.678  56.238  1.00 150.48 ? 377  TYR A OH  1 
ATOM   2725 N N   . PRO A 1 419  ? 119.099 94.318  53.664  1.00 152.14 ? 378  PRO A N   1 
ATOM   2726 C CA  . PRO A 1 419  ? 117.812 94.038  54.320  1.00 152.14 ? 378  PRO A CA  1 
ATOM   2727 C C   . PRO A 1 419  ? 117.028 95.281  54.709  1.00 152.14 ? 378  PRO A C   1 
ATOM   2728 O O   . PRO A 1 419  ? 115.811 95.334  54.500  1.00 152.14 ? 378  PRO A O   1 
ATOM   2729 C CB  . PRO A 1 419  ? 118.221 93.234  55.561  1.00 152.14 ? 378  PRO A CB  1 
ATOM   2730 C CG  . PRO A 1 419  ? 119.636 93.616  55.813  1.00 152.14 ? 378  PRO A CG  1 
ATOM   2731 C CD  . PRO A 1 419  ? 120.242 93.847  54.463  1.00 152.14 ? 378  PRO A CD  1 
ATOM   2732 N N   . SER A 1 420  ? 117.702 96.279  55.281  1.00 151.63 ? 379  SER A N   1 
ATOM   2733 C CA  . SER A 1 420  ? 116.995 97.470  55.744  1.00 151.63 ? 379  SER A CA  1 
ATOM   2734 C C   . SER A 1 420  ? 116.384 98.235  54.577  1.00 151.63 ? 379  SER A C   1 
ATOM   2735 O O   . SER A 1 420  ? 115.222 98.654  54.635  1.00 151.63 ? 379  SER A O   1 
ATOM   2736 C CB  . SER A 1 420  ? 117.944 98.369  56.535  1.00 151.63 ? 379  SER A CB  1 
ATOM   2737 O OG  . SER A 1 420  ? 118.935 98.932  55.694  1.00 151.63 ? 379  SER A OG  1 
ATOM   2738 N N   . ARG A 1 421  ? 117.151 98.420  53.506  1.00 155.42 ? 380  ARG A N   1 
ATOM   2739 C CA  . ARG A 1 421  ? 116.720 99.212  52.360  1.00 155.42 ? 380  ARG A CA  1 
ATOM   2740 C C   . ARG A 1 421  ? 116.721 98.377  51.080  1.00 155.42 ? 380  ARG A C   1 
ATOM   2741 O O   . ARG A 1 421  ? 117.790 98.097  50.515  1.00 155.42 ? 380  ARG A O   1 
ATOM   2742 C CB  . ARG A 1 421  ? 117.610 100.457 52.226  1.00 155.42 ? 380  ARG A CB  1 
ATOM   2743 C CG  . ARG A 1 421  ? 119.092 100.210 51.969  1.00 155.42 ? 380  ARG A CG  1 
ATOM   2744 C CD  . ARG A 1 421  ? 119.859 101.511 51.861  1.00 155.42 ? 380  ARG A CD  1 
ATOM   2745 N NE  . ARG A 1 421  ? 119.840 102.251 53.117  1.00 155.42 ? 380  ARG A NE  1 
ATOM   2746 C CZ  . ARG A 1 421  ? 120.726 102.090 54.091  1.00 155.42 ? 380  ARG A CZ  1 
ATOM   2747 N NH1 . ARG A 1 421  ? 121.719 101.223 53.985  1.00 155.42 ? 380  ARG A NH1 1 
ATOM   2748 N NH2 . ARG A 1 421  ? 120.610 102.815 55.199  1.00 155.42 ? 380  ARG A NH2 1 
ATOM   2749 N N   . PRO A 1 422  ? 115.559 97.921  50.604  1.00 159.12 ? 381  PRO A N   1 
ATOM   2750 C CA  . PRO A 1 422  ? 115.532 97.094  49.391  1.00 159.12 ? 381  PRO A CA  1 
ATOM   2751 C C   . PRO A 1 422  ? 115.590 97.886  48.098  1.00 159.12 ? 381  PRO A C   1 
ATOM   2752 O O   . PRO A 1 422  ? 115.663 97.275  47.023  1.00 159.12 ? 381  PRO A O   1 
ATOM   2753 C CB  . PRO A 1 422  ? 114.199 96.347  49.515  1.00 159.12 ? 381  PRO A CB  1 
ATOM   2754 C CG  . PRO A 1 422  ? 113.328 97.278  50.289  1.00 159.12 ? 381  PRO A CG  1 
ATOM   2755 C CD  . PRO A 1 422  ? 114.223 98.083  51.201  1.00 159.12 ? 381  PRO A CD  1 
ATOM   2756 N N   . ASP A 1 423  ? 115.550 99.219  48.163  1.00 162.06 ? 382  ASP A N   1 
ATOM   2757 C CA  . ASP A 1 423  ? 115.579 100.021 46.943  1.00 162.06 ? 382  ASP A CA  1 
ATOM   2758 C C   . ASP A 1 423  ? 116.901 99.862  46.203  1.00 162.06 ? 382  ASP A C   1 
ATOM   2759 O O   . ASP A 1 423  ? 116.918 99.695  44.978  1.00 162.06 ? 382  ASP A O   1 
ATOM   2760 C CB  . ASP A 1 423  ? 115.331 101.490 47.280  1.00 162.06 ? 382  ASP A CB  1 
ATOM   2761 C CG  . ASP A 1 423  ? 116.210 101.982 48.411  1.00 162.06 ? 382  ASP A CG  1 
ATOM   2762 O OD1 . ASP A 1 423  ? 116.118 101.422 49.523  1.00 162.06 ? 382  ASP A OD1 1 
ATOM   2763 O OD2 . ASP A 1 423  ? 117.000 102.924 48.188  1.00 162.06 ? 382  ASP A OD2 1 
ATOM   2764 N N   . VAL A 1 424  ? 118.015 99.905  46.927  1.00 161.09 ? 383  VAL A N   1 
ATOM   2765 C CA  . VAL A 1 424  ? 119.347 99.823  46.342  1.00 161.09 ? 383  VAL A CA  1 
ATOM   2766 C C   . VAL A 1 424  ? 119.953 98.473  46.686  1.00 161.09 ? 383  VAL A C   1 
ATOM   2767 O O   . VAL A 1 424  ? 119.859 98.007  47.828  1.00 161.09 ? 383  VAL A O   1 
ATOM   2768 C CB  . VAL A 1 424  ? 120.252 100.974 46.825  1.00 161.09 ? 383  VAL A CB  1 
ATOM   2769 C CG1 . VAL A 1 424  ? 119.846 102.278 46.163  1.00 161.09 ? 383  VAL A CG1 1 
ATOM   2770 C CG2 . VAL A 1 424  ? 120.184 101.105 48.334  1.00 161.09 ? 383  VAL A CG2 1 
ATOM   2771 N N   . LYS A 1 425  ? 120.566 97.839  45.691  1.00 158.54 ? 384  LYS A N   1 
ATOM   2772 C CA  . LYS A 1 425  ? 121.217 96.551  45.867  1.00 158.54 ? 384  LYS A CA  1 
ATOM   2773 C C   . LYS A 1 425  ? 122.664 96.652  45.409  1.00 158.54 ? 384  LYS A C   1 
ATOM   2774 O O   . LYS A 1 425  ? 123.007 97.471  44.552  1.00 158.54 ? 384  LYS A O   1 
ATOM   2775 C CB  . LYS A 1 425  ? 120.485 95.443  45.096  1.00 158.54 ? 384  LYS A CB  1 
ATOM   2776 C CG  . LYS A 1 425  ? 120.973 95.236  43.673  1.00 158.54 ? 384  LYS A CG  1 
ATOM   2777 C CD  . LYS A 1 425  ? 120.021 94.346  42.895  1.00 158.54 ? 384  LYS A CD  1 
ATOM   2778 C CE  . LYS A 1 425  ? 118.704 95.053  42.630  1.00 158.54 ? 384  LYS A CE  1 
ATOM   2779 N NZ  . LYS A 1 425  ? 118.908 96.361  41.948  1.00 158.54 ? 384  LYS A NZ  1 
ATOM   2780 N N   . ILE A 1 426  ? 123.517 95.820  46.002  1.00 160.45 ? 385  ILE A N   1 
ATOM   2781 C CA  . ILE A 1 426  ? 124.947 95.806  45.706  1.00 160.45 ? 385  ILE A CA  1 
ATOM   2782 C C   . ILE A 1 426  ? 125.334 94.550  44.931  1.00 160.45 ? 385  ILE A C   1 
ATOM   2783 O O   . ILE A 1 426  ? 125.818 94.631  43.801  1.00 160.45 ? 385  ILE A O   1 
ATOM   2784 C CB  . ILE A 1 426  ? 125.788 95.947  46.995  1.00 160.45 ? 385  ILE A CB  1 
ATOM   2785 C CG1 . ILE A 1 426  ? 125.525 97.289  47.684  1.00 160.45 ? 385  ILE A CG1 1 
ATOM   2786 C CG2 . ILE A 1 426  ? 127.265 95.801  46.678  1.00 160.45 ? 385  ILE A CG2 1 
ATOM   2787 C CD1 . ILE A 1 426  ? 124.377 97.271  48.678  1.00 160.45 ? 385  ILE A CD1 1 
ATOM   2788 N N   . LEU A 1 427  ? 125.126 93.377  45.527  1.00 161.52 ? 386  LEU A N   1 
ATOM   2789 C CA  . LEU A 1 427  ? 125.420 92.099  44.882  1.00 161.52 ? 386  LEU A CA  1 
ATOM   2790 C C   . LEU A 1 427  ? 124.241 91.769  43.971  1.00 161.52 ? 386  LEU A C   1 
ATOM   2791 O O   . LEU A 1 427  ? 123.334 91.012  44.318  1.00 161.52 ? 386  LEU A O   1 
ATOM   2792 C CB  . LEU A 1 427  ? 125.652 91.014  45.927  1.00 161.52 ? 386  LEU A CB  1 
ATOM   2793 C CG  . LEU A 1 427  ? 127.036 90.835  46.566  1.00 161.52 ? 386  LEU A CG  1 
ATOM   2794 C CD1 . LEU A 1 427  ? 128.025 90.256  45.583  1.00 161.52 ? 386  LEU A CD1 1 
ATOM   2795 C CD2 . LEU A 1 427  ? 127.566 92.145  47.119  1.00 161.52 ? 386  LEU A CD2 1 
ATOM   2796 N N   . ASN A 1 428  ? 124.253 92.368  42.779  1.00 165.18 ? 387  ASN A N   1 
ATOM   2797 C CA  . ASN A 1 428  ? 123.047 92.378  41.950  1.00 165.18 ? 387  ASN A CA  1 
ATOM   2798 C C   . ASN A 1 428  ? 122.875 91.086  41.154  1.00 165.18 ? 387  ASN A C   1 
ATOM   2799 O O   . ASN A 1 428  ? 121.924 90.331  41.377  1.00 165.18 ? 387  ASN A O   1 
ATOM   2800 C CB  . ASN A 1 428  ? 123.072 93.596  41.019  1.00 165.18 ? 387  ASN A CB  1 
ATOM   2801 C CG  . ASN A 1 428  ? 124.430 93.822  40.390  1.00 165.18 ? 387  ASN A CG  1 
ATOM   2802 O OD1 . ASN A 1 428  ? 124.994 92.921  39.773  1.00 165.18 ? 387  ASN A OD1 1 
ATOM   2803 N ND2 . ASN A 1 428  ? 124.963 95.026  40.548  1.00 165.18 ? 387  ASN A ND2 1 
ATOM   2804 N N   . ASN A 1 429  ? 123.784 90.814  40.217  1.00 169.40 ? 388  ASN A N   1 
ATOM   2805 C CA  . ASN A 1 429  ? 123.604 89.682  39.317  1.00 169.40 ? 388  ASN A CA  1 
ATOM   2806 C C   . ASN A 1 429  ? 124.886 88.936  38.976  1.00 169.40 ? 388  ASN A C   1 
ATOM   2807 O O   . ASN A 1 429  ? 124.835 88.014  38.157  1.00 169.40 ? 388  ASN A O   1 
ATOM   2808 C CB  . ASN A 1 429  ? 122.940 90.146  38.009  1.00 169.40 ? 388  ASN A CB  1 
ATOM   2809 C CG  . ASN A 1 429  ? 121.518 90.631  38.216  1.00 169.40 ? 388  ASN A CG  1 
ATOM   2810 O OD1 . ASN A 1 429  ? 120.694 89.935  38.811  1.00 169.40 ? 388  ASN A OD1 1 
ATOM   2811 N ND2 . ASN A 1 429  ? 121.225 91.829  37.727  1.00 169.40 ? 388  ASN A ND2 1 
ATOM   2812 N N   . PHE A 1 430  ? 126.020 89.292  39.564  1.00 168.72 ? 389  PHE A N   1 
ATOM   2813 C CA  . PHE A 1 430  ? 127.309 88.771  39.139  1.00 168.72 ? 389  PHE A CA  1 
ATOM   2814 C C   . PHE A 1 430  ? 127.778 87.640  40.049  1.00 168.72 ? 389  PHE A C   1 
ATOM   2815 O O   . PHE A 1 430  ? 127.261 87.426  41.148  1.00 168.72 ? 389  PHE A O   1 
ATOM   2816 C CB  . PHE A 1 430  ? 128.352 89.891  39.103  1.00 168.72 ? 389  PHE A CB  1 
ATOM   2817 C CG  . PHE A 1 430  ? 128.462 90.651  40.390  1.00 168.72 ? 389  PHE A CG  1 
ATOM   2818 C CD1 . PHE A 1 430  ? 127.608 91.703  40.659  1.00 168.72 ? 389  PHE A CD1 1 
ATOM   2819 C CD2 . PHE A 1 430  ? 129.415 90.311  41.332  1.00 168.72 ? 389  PHE A CD2 1 
ATOM   2820 C CE1 . PHE A 1 430  ? 127.698 92.401  41.840  1.00 168.72 ? 389  PHE A CE1 1 
ATOM   2821 C CE2 . PHE A 1 430  ? 129.513 91.009  42.514  1.00 168.72 ? 389  PHE A CE2 1 
ATOM   2822 C CZ  . PHE A 1 430  ? 128.654 92.059  42.767  1.00 168.72 ? 389  PHE A CZ  1 
ATOM   2823 N N   . CYS A 1 431  ? 128.783 86.915  39.567  1.00 169.36 ? 390  CYS A N   1 
ATOM   2824 C CA  . CYS A 1 431  ? 129.387 85.806  40.283  1.00 169.36 ? 390  CYS A CA  1 
ATOM   2825 C C   . CYS A 1 431  ? 130.837 86.139  40.600  1.00 169.36 ? 390  CYS A C   1 
ATOM   2826 O O   . CYS A 1 431  ? 131.476 86.927  39.898  1.00 169.36 ? 390  CYS A O   1 
ATOM   2827 C CB  . CYS A 1 431  ? 129.323 84.513  39.462  1.00 169.36 ? 390  CYS A CB  1 
ATOM   2828 S SG  . CYS A 1 431  ? 127.681 84.102  38.841  1.00 169.36 ? 390  CYS A SG  1 
ATOM   2829 N N   . LEU A 1 432  ? 131.355 85.530  41.664  1.00 166.48 ? 391  LEU A N   1 
ATOM   2830 C CA  . LEU A 1 432  ? 132.727 85.763  42.093  1.00 166.48 ? 391  LEU A CA  1 
ATOM   2831 C C   . LEU A 1 432  ? 133.613 84.546  41.860  1.00 166.48 ? 391  LEU A C   1 
ATOM   2832 O O   . LEU A 1 432  ? 134.657 84.665  41.212  1.00 166.48 ? 391  LEU A O   1 
ATOM   2833 C CB  . LEU A 1 432  ? 132.754 86.176  43.570  1.00 166.48 ? 391  LEU A CB  1 
ATOM   2834 C CG  . LEU A 1 432  ? 132.529 87.667  43.844  1.00 166.48 ? 391  LEU A CG  1 
ATOM   2835 C CD1 . LEU A 1 432  ? 131.048 88.025  43.811  1.00 166.48 ? 391  LEU A CD1 1 
ATOM   2836 C CD2 . LEU A 1 432  ? 133.150 88.064  45.172  1.00 166.48 ? 391  LEU A CD2 1 
ATOM   2837 N N   . SER A 1 433  ? 133.223 83.381  42.384  1.00 164.38 ? 392  SER A N   1 
ATOM   2838 C CA  . SER A 1 433  ? 133.929 82.116  42.184  1.00 164.38 ? 392  SER A CA  1 
ATOM   2839 C C   . SER A 1 433  ? 135.299 82.114  42.854  1.00 164.38 ? 392  SER A C   1 
ATOM   2840 O O   . SER A 1 433  ? 135.941 83.159  42.987  1.00 164.38 ? 392  SER A O   1 
ATOM   2841 C CB  . SER A 1 433  ? 134.067 81.798  40.691  1.00 164.38 ? 392  SER A CB  1 
ATOM   2842 O OG  . SER A 1 433  ? 135.152 82.508  40.120  1.00 164.38 ? 392  SER A OG  1 
ATOM   2843 N N   . VAL A 1 434  ? 135.751 80.942  43.289  1.00 163.94 ? 393  VAL A N   1 
ATOM   2844 C CA  . VAL A 1 434  ? 137.042 80.805  43.961  1.00 163.94 ? 393  VAL A CA  1 
ATOM   2845 C C   . VAL A 1 434  ? 137.718 79.530  43.484  1.00 163.94 ? 393  VAL A C   1 
ATOM   2846 O O   . VAL A 1 434  ? 137.068 78.627  42.942  1.00 163.94 ? 393  VAL A O   1 
ATOM   2847 C CB  . VAL A 1 434  ? 136.895 80.769  45.497  1.00 163.94 ? 393  VAL A CB  1 
ATOM   2848 C CG1 . VAL A 1 434  ? 136.189 82.015  46.018  1.00 163.94 ? 393  VAL A CG1 1 
ATOM   2849 C CG2 . VAL A 1 434  ? 136.167 79.511  45.929  1.00 163.94 ? 393  VAL A CG2 1 
ATOM   2850 N N   . PRO A 1 435  ? 139.033 79.443  43.645  1.00 161.55 ? 394  PRO A N   1 
ATOM   2851 C CA  . PRO A 1 435  ? 139.727 78.164  43.477  1.00 161.55 ? 394  PRO A CA  1 
ATOM   2852 C C   . PRO A 1 435  ? 139.640 77.351  44.765  1.00 161.55 ? 394  PRO A C   1 
ATOM   2853 O O   . PRO A 1 435  ? 138.999 77.744  45.736  1.00 161.55 ? 394  PRO A O   1 
ATOM   2854 C CB  . PRO A 1 435  ? 141.168 78.581  43.173  1.00 161.55 ? 394  PRO A CB  1 
ATOM   2855 C CG  . PRO A 1 435  ? 141.311 79.901  43.829  1.00 161.55 ? 394  PRO A CG  1 
ATOM   2856 C CD  . PRO A 1 435  ? 139.976 80.572  43.703  1.00 161.55 ? 394  PRO A CD  1 
ATOM   2857 N N   . ALA A 1 436  ? 140.307 76.203  44.758  1.00 161.01 ? 395  ALA A N   1 
ATOM   2858 C CA  . ALA A 1 436  ? 140.369 75.316  45.916  1.00 161.01 ? 395  ALA A CA  1 
ATOM   2859 C C   . ALA A 1 436  ? 141.788 75.372  46.476  1.00 161.01 ? 395  ALA A C   1 
ATOM   2860 O O   . ALA A 1 436  ? 142.642 74.557  46.126  1.00 161.01 ? 395  ALA A O   1 
ATOM   2861 C CB  . ALA A 1 436  ? 139.971 73.893  45.542  1.00 161.01 ? 395  ALA A CB  1 
ATOM   2862 N N   . GLY A 1 437  ? 142.033 76.340  47.355  1.00 157.66 ? 396  GLY A N   1 
ATOM   2863 C CA  . GLY A 1 437  ? 143.323 76.448  48.003  1.00 157.66 ? 396  GLY A CA  1 
ATOM   2864 C C   . GLY A 1 437  ? 144.239 77.504  47.417  1.00 157.66 ? 396  GLY A C   1 
ATOM   2865 O O   . GLY A 1 437  ? 145.438 77.264  47.247  1.00 157.66 ? 396  GLY A O   1 
ATOM   2866 N N   . LYS A 1 438  ? 143.691 78.676  47.104  1.00 156.33 ? 397  LYS A N   1 
ATOM   2867 C CA  . LYS A 1 438  ? 144.498 79.785  46.612  1.00 156.33 ? 397  LYS A CA  1 
ATOM   2868 C C   . LYS A 1 438  ? 143.803 81.094  46.950  1.00 156.33 ? 397  LYS A C   1 
ATOM   2869 O O   . LYS A 1 438  ? 142.608 81.248  46.687  1.00 156.33 ? 397  LYS A O   1 
ATOM   2870 C CB  . LYS A 1 438  ? 144.733 79.675  45.102  1.00 156.33 ? 397  LYS A CB  1 
ATOM   2871 C CG  . LYS A 1 438  ? 146.037 80.301  44.639  1.00 156.33 ? 397  LYS A CG  1 
ATOM   2872 C CD  . LYS A 1 438  ? 147.221 79.757  45.415  1.00 156.33 ? 397  LYS A CD  1 
ATOM   2873 C CE  . LYS A 1 438  ? 148.463 80.598  45.181  1.00 156.33 ? 397  LYS A CE  1 
ATOM   2874 N NZ  . LYS A 1 438  ? 148.302 81.977  45.718  1.00 156.33 ? 397  LYS A NZ  1 
ATOM   2875 N N   . THR A 1 439  ? 144.558 82.029  47.517  1.00 156.84 ? 398  THR A N   1 
ATOM   2876 C CA  . THR A 1 439  ? 143.987 83.267  48.026  1.00 156.84 ? 398  THR A CA  1 
ATOM   2877 C C   . THR A 1 439  ? 143.465 84.147  46.894  1.00 156.84 ? 398  THR A C   1 
ATOM   2878 O O   . THR A 1 439  ? 143.917 84.064  45.750  1.00 156.84 ? 398  THR A O   1 
ATOM   2879 C CB  . THR A 1 439  ? 145.028 84.038  48.834  1.00 156.84 ? 398  THR A CB  1 
ATOM   2880 O OG1 . THR A 1 439  ? 145.920 84.712  47.940  1.00 156.84 ? 398  THR A OG1 1 
ATOM   2881 C CG2 . THR A 1 439  ? 145.831 83.084  49.700  1.00 156.84 ? 398  THR A CG2 1 
ATOM   2882 N N   . ILE A 1 440  ? 142.495 84.995  47.230  1.00 153.17 ? 399  ILE A N   1 
ATOM   2883 C CA  . ILE A 1 440  ? 141.924 85.969  46.308  1.00 153.17 ? 399  ILE A CA  1 
ATOM   2884 C C   . ILE A 1 440  ? 141.917 87.329  46.990  1.00 153.17 ? 399  ILE A C   1 
ATOM   2885 O O   . ILE A 1 440  ? 141.492 87.446  48.143  1.00 153.17 ? 399  ILE A O   1 
ATOM   2886 C CB  . ILE A 1 440  ? 140.497 85.588  45.872  1.00 153.17 ? 399  ILE A CB  1 
ATOM   2887 C CG1 . ILE A 1 440  ? 140.506 84.305  45.045  1.00 153.17 ? 399  ILE A CG1 1 
ATOM   2888 C CG2 . ILE A 1 440  ? 139.852 86.717  45.086  1.00 153.17 ? 399  ILE A CG2 1 
ATOM   2889 C CD1 . ILE A 1 440  ? 139.124 83.789  44.759  1.00 153.17 ? 399  ILE A CD1 1 
ATOM   2890 N N   . ALA A 1 441  ? 142.380 88.351  46.277  1.00 156.91 ? 400  ALA A N   1 
ATOM   2891 C CA  . ALA A 1 441  ? 142.352 89.722  46.764  1.00 156.91 ? 400  ALA A CA  1 
ATOM   2892 C C   . ALA A 1 441  ? 141.177 90.455  46.134  1.00 156.91 ? 400  ALA A C   1 
ATOM   2893 O O   . ALA A 1 441  ? 140.969 90.376  44.919  1.00 156.91 ? 400  ALA A O   1 
ATOM   2894 C CB  . ALA A 1 441  ? 143.661 90.444  46.443  1.00 156.91 ? 400  ALA A CB  1 
ATOM   2895 N N   . LEU A 1 442  ? 140.410 91.161  46.959  1.00 158.28 ? 401  LEU A N   1 
ATOM   2896 C CA  . LEU A 1 442  ? 139.227 91.882  46.510  1.00 158.28 ? 401  LEU A CA  1 
ATOM   2897 C C   . LEU A 1 442  ? 139.436 93.367  46.762  1.00 158.28 ? 401  LEU A C   1 
ATOM   2898 O O   . LEU A 1 442  ? 139.663 93.779  47.906  1.00 158.28 ? 401  LEU A O   1 
ATOM   2899 C CB  . LEU A 1 442  ? 137.977 91.378  47.236  1.00 158.28 ? 401  LEU A CB  1 
ATOM   2900 C CG  . LEU A 1 442  ? 136.645 91.995  46.819  1.00 158.28 ? 401  LEU A CG  1 
ATOM   2901 C CD1 . LEU A 1 442  ? 136.363 91.673  45.363  1.00 158.28 ? 401  LEU A CD1 1 
ATOM   2902 C CD2 . LEU A 1 442  ? 135.521 91.499  47.711  1.00 158.28 ? 401  LEU A CD2 1 
ATOM   2903 N N   . VAL A 1 443  ? 139.365 94.168  45.700  1.00 164.45 ? 402  VAL A N   1 
ATOM   2904 C CA  . VAL A 1 443  ? 139.552 95.618  45.782  1.00 164.45 ? 402  VAL A CA  1 
ATOM   2905 C C   . VAL A 1 443  ? 138.405 96.256  45.002  1.00 164.45 ? 402  VAL A C   1 
ATOM   2906 O O   . VAL A 1 443  ? 138.474 96.410  43.780  1.00 164.45 ? 402  VAL A O   1 
ATOM   2907 C CB  . VAL A 1 443  ? 140.907 96.075  45.234  1.00 164.45 ? 402  VAL A CB  1 
ATOM   2908 C CG1 . VAL A 1 443  ? 141.099 97.561  45.489  1.00 164.45 ? 402  VAL A CG1 1 
ATOM   2909 C CG2 . VAL A 1 443  ? 142.041 95.274  45.849  1.00 164.45 ? 402  VAL A CG2 1 
ATOM   2910 N N   . GLY A 1 444  ? 137.343 96.634  45.705  1.00 167.08 ? 403  GLY A N   1 
ATOM   2911 C CA  . GLY A 1 444  ? 136.236 97.308  45.056  1.00 167.08 ? 403  GLY A CA  1 
ATOM   2912 C C   . GLY A 1 444  ? 136.060 98.746  45.496  1.00 167.08 ? 403  GLY A C   1 
ATOM   2913 O O   . GLY A 1 444  ? 135.580 99.002  46.605  1.00 167.08 ? 403  GLY A O   1 
ATOM   2914 N N   . SER A 1 445  ? 136.424 99.684  44.618  1.00 169.80 ? 404  SER A N   1 
ATOM   2915 C CA  . SER A 1 445  ? 136.297 101.123 44.843  1.00 169.80 ? 404  SER A CA  1 
ATOM   2916 C C   . SER A 1 445  ? 136.609 101.522 46.280  1.00 169.80 ? 404  SER A C   1 
ATOM   2917 O O   . SER A 1 445  ? 137.632 101.115 46.840  1.00 169.80 ? 404  SER A O   1 
ATOM   2918 C CB  . SER A 1 445  ? 134.891 101.596 44.470  1.00 169.80 ? 404  SER A CB  1 
ATOM   2919 O OG  . SER A 1 445  ? 133.933 101.140 45.408  1.00 169.80 ? 404  SER A OG  1 
ATOM   2920 N N   . SER A 1 446  ? 135.728 102.320 46.880  1.00 169.45 ? 405  SER A N   1 
ATOM   2921 C CA  . SER A 1 446  ? 135.827 102.686 48.286  1.00 169.45 ? 405  SER A CA  1 
ATOM   2922 C C   . SER A 1 446  ? 134.606 102.257 49.080  1.00 169.45 ? 405  SER A C   1 
ATOM   2923 O O   . SER A 1 446  ? 134.746 101.637 50.142  1.00 169.45 ? 405  SER A O   1 
ATOM   2924 C CB  . SER A 1 446  ? 136.036 104.203 48.422  1.00 169.45 ? 405  SER A CB  1 
ATOM   2925 O OG  . SER A 1 446  ? 137.090 104.650 47.585  1.00 169.45 ? 405  SER A OG  1 
ATOM   2926 N N   . GLY A 1 447  ? 133.407 102.562 48.593  1.00 167.81 ? 406  GLY A N   1 
ATOM   2927 C CA  . GLY A 1 447  ? 132.186 102.216 49.293  1.00 167.81 ? 406  GLY A CA  1 
ATOM   2928 C C   . GLY A 1 447  ? 131.468 101.017 48.709  1.00 167.81 ? 406  GLY A C   1 
ATOM   2929 O O   . GLY A 1 447  ? 130.281 100.810 48.973  1.00 167.81 ? 406  GLY A O   1 
ATOM   2930 N N   . SER A 1 448  ? 132.173 100.223 47.908  1.00 164.55 ? 407  SER A N   1 
ATOM   2931 C CA  . SER A 1 448  ? 131.568 99.039  47.321  1.00 164.55 ? 407  SER A CA  1 
ATOM   2932 C C   . SER A 1 448  ? 131.302 97.986  48.393  1.00 164.55 ? 407  SER A C   1 
ATOM   2933 O O   . SER A 1 448  ? 131.854 98.025  49.496  1.00 164.55 ? 407  SER A O   1 
ATOM   2934 C CB  . SER A 1 448  ? 132.466 98.460  46.229  1.00 164.55 ? 407  SER A CB  1 
ATOM   2935 O OG  . SER A 1 448  ? 131.942 97.243  45.732  1.00 164.55 ? 407  SER A OG  1 
ATOM   2936 N N   . GLY A 1 449  ? 130.440 97.032  48.052  1.00 152.94 ? 408  GLY A N   1 
ATOM   2937 C CA  . GLY A 1 449  ? 130.062 95.990  48.984  1.00 152.94 ? 408  GLY A CA  1 
ATOM   2938 C C   . GLY A 1 449  ? 131.116 94.918  49.160  1.00 152.94 ? 408  GLY A C   1 
ATOM   2939 O O   . GLY A 1 449  ? 130.833 93.727  48.999  1.00 152.94 ? 408  GLY A O   1 
ATOM   2940 N N   . LYS A 1 450  ? 132.342 95.330  49.483  1.00 150.11 ? 409  LYS A N   1 
ATOM   2941 C CA  . LYS A 1 450  ? 133.403 94.360  49.732  1.00 150.11 ? 409  LYS A CA  1 
ATOM   2942 C C   . LYS A 1 450  ? 133.099 93.515  50.963  1.00 150.11 ? 409  LYS A C   1 
ATOM   2943 O O   . LYS A 1 450  ? 133.317 92.299  50.958  1.00 150.11 ? 409  LYS A O   1 
ATOM   2944 C CB  . LYS A 1 450  ? 134.743 95.077  49.886  1.00 150.11 ? 409  LYS A CB  1 
ATOM   2945 C CG  . LYS A 1 450  ? 135.117 95.953  48.702  1.00 150.11 ? 409  LYS A CG  1 
ATOM   2946 C CD  . LYS A 1 450  ? 136.438 96.662  48.938  1.00 150.11 ? 409  LYS A CD  1 
ATOM   2947 C CE  . LYS A 1 450  ? 136.367 97.571  50.153  1.00 150.11 ? 409  LYS A CE  1 
ATOM   2948 N NZ  . LYS A 1 450  ? 135.361 98.654  49.982  1.00 150.11 ? 409  LYS A NZ  1 
ATOM   2949 N N   . SER A 1 451  ? 132.588 94.142  52.025  1.00 136.41 ? 410  SER A N   1 
ATOM   2950 C CA  . SER A 1 451  ? 132.237 93.401  53.231  1.00 136.41 ? 410  SER A CA  1 
ATOM   2951 C C   . SER A 1 451  ? 131.009 92.524  53.033  1.00 136.41 ? 410  SER A C   1 
ATOM   2952 O O   . SER A 1 451  ? 130.787 91.603  53.826  1.00 136.41 ? 410  SER A O   1 
ATOM   2953 C CB  . SER A 1 451  ? 132.000 94.369  54.390  1.00 136.41 ? 410  SER A CB  1 
ATOM   2954 O OG  . SER A 1 451  ? 133.039 95.329  54.469  1.00 136.41 ? 410  SER A OG  1 
ATOM   2955 N N   . THR A 1 452  ? 130.206 92.795  52.003  1.00 134.65 ? 411  THR A N   1 
ATOM   2956 C CA  . THR A 1 452  ? 129.002 92.005  51.779  1.00 134.65 ? 411  THR A CA  1 
ATOM   2957 C C   . THR A 1 452  ? 129.342 90.563  51.430  1.00 134.65 ? 411  THR A C   1 
ATOM   2958 O O   . THR A 1 452  ? 128.650 89.635  51.861  1.00 134.65 ? 411  THR A O   1 
ATOM   2959 C CB  . THR A 1 452  ? 128.156 92.638  50.679  1.00 134.65 ? 411  THR A CB  1 
ATOM   2960 O OG1 . THR A 1 452  ? 128.049 94.046  50.913  1.00 134.65 ? 411  THR A OG1 1 
ATOM   2961 C CG2 . THR A 1 452  ? 126.768 92.028  50.671  1.00 134.65 ? 411  THR A CG2 1 
ATOM   2962 N N   . VAL A 1 453  ? 130.400 90.350  50.645  1.00 129.76 ? 412  VAL A N   1 
ATOM   2963 C CA  . VAL A 1 453  ? 130.808 88.988  50.313  1.00 129.76 ? 412  VAL A CA  1 
ATOM   2964 C C   . VAL A 1 453  ? 131.245 88.243  51.566  1.00 129.76 ? 412  VAL A C   1 
ATOM   2965 O O   . VAL A 1 453  ? 130.905 87.069  51.762  1.00 129.76 ? 412  VAL A O   1 
ATOM   2966 C CB  . VAL A 1 453  ? 131.921 89.006  49.252  1.00 129.76 ? 412  VAL A CB  1 
ATOM   2967 C CG1 . VAL A 1 453  ? 132.206 87.596  48.769  1.00 129.76 ? 412  VAL A CG1 1 
ATOM   2968 C CG2 . VAL A 1 453  ? 131.529 89.904  48.093  1.00 129.76 ? 412  VAL A CG2 1 
ATOM   2969 N N   . VAL A 1 454  ? 132.007 88.912  52.432  1.00 125.44 ? 413  VAL A N   1 
ATOM   2970 C CA  . VAL A 1 454  ? 132.429 88.298  53.687  1.00 125.44 ? 413  VAL A CA  1 
ATOM   2971 C C   . VAL A 1 454  ? 131.218 87.936  54.535  1.00 125.44 ? 413  VAL A C   1 
ATOM   2972 O O   . VAL A 1 454  ? 131.146 86.841  55.106  1.00 125.44 ? 413  VAL A O   1 
ATOM   2973 C CB  . VAL A 1 454  ? 133.386 89.238  54.441  1.00 125.44 ? 413  VAL A CB  1 
ATOM   2974 C CG1 . VAL A 1 454  ? 133.712 88.676  55.812  1.00 125.44 ? 413  VAL A CG1 1 
ATOM   2975 C CG2 . VAL A 1 454  ? 134.653 89.461  53.633  1.00 125.44 ? 413  VAL A CG2 1 
ATOM   2976 N N   . SER A 1 455  ? 130.247 88.847  54.627  1.00 120.93 ? 414  SER A N   1 
ATOM   2977 C CA  . SER A 1 455  ? 129.051 88.578  55.417  1.00 120.93 ? 414  SER A CA  1 
ATOM   2978 C C   . SER A 1 455  ? 128.257 87.409  54.846  1.00 120.93 ? 414  SER A C   1 
ATOM   2979 O O   . SER A 1 455  ? 127.750 86.568  55.596  1.00 120.93 ? 414  SER A O   1 
ATOM   2980 C CB  . SER A 1 455  ? 128.182 89.830  55.489  1.00 120.93 ? 414  SER A CB  1 
ATOM   2981 O OG  . SER A 1 455  ? 128.897 90.908  56.066  1.00 120.93 ? 414  SER A OG  1 
ATOM   2982 N N   . LEU A 1 456  ? 128.133 87.345  53.519  1.00 122.59 ? 415  LEU A N   1 
ATOM   2983 C CA  . LEU A 1 456  ? 127.401 86.250  52.891  1.00 122.59 ? 415  LEU A CA  1 
ATOM   2984 C C   . LEU A 1 456  ? 128.100 84.916  53.109  1.00 122.59 ? 415  LEU A C   1 
ATOM   2985 O O   . LEU A 1 456  ? 127.440 83.892  53.321  1.00 122.59 ? 415  LEU A O   1 
ATOM   2986 C CB  . LEU A 1 456  ? 127.219 86.524  51.399  1.00 122.59 ? 415  LEU A CB  1 
ATOM   2987 C CG  . LEU A 1 456  ? 125.909 87.183  50.966  1.00 122.59 ? 415  LEU A CG  1 
ATOM   2988 C CD1 . LEU A 1 456  ? 124.753 86.237  51.209  1.00 122.59 ? 415  LEU A CD1 1 
ATOM   2989 C CD2 . LEU A 1 456  ? 125.676 88.495  51.690  1.00 122.59 ? 415  LEU A CD2 1 
ATOM   2990 N N   . ILE A 1 457  ? 129.431 84.902  53.046  1.00 121.05 ? 416  ILE A N   1 
ATOM   2991 C CA  . ILE A 1 457  ? 130.166 83.661  53.277  1.00 121.05 ? 416  ILE A CA  1 
ATOM   2992 C C   . ILE A 1 457  ? 129.942 83.172  54.702  1.00 121.05 ? 416  ILE A C   1 
ATOM   2993 O O   . ILE A 1 457  ? 129.715 81.979  54.939  1.00 121.05 ? 416  ILE A O   1 
ATOM   2994 C CB  . ILE A 1 457  ? 131.661 83.862  52.971  1.00 121.05 ? 416  ILE A CB  1 
ATOM   2995 C CG1 . ILE A 1 457  ? 131.895 83.858  51.461  1.00 121.05 ? 416  ILE A CG1 1 
ATOM   2996 C CG2 . ILE A 1 457  ? 132.491 82.776  53.627  1.00 121.05 ? 416  ILE A CG2 1 
ATOM   2997 C CD1 . ILE A 1 457  ? 131.628 82.522  50.812  1.00 121.05 ? 416  ILE A CD1 1 
ATOM   2998 N N   . GLU A 1 458  ? 129.985 84.086  55.671  1.00 118.63 ? 417  GLU A N   1 
ATOM   2999 C CA  . GLU A 1 458  ? 129.760 83.746  57.071  1.00 118.63 ? 417  GLU A CA  1 
ATOM   3000 C C   . GLU A 1 458  ? 128.301 83.460  57.387  1.00 118.63 ? 417  GLU A C   1 
ATOM   3001 O O   . GLU A 1 458  ? 127.986 83.204  58.553  1.00 118.63 ? 417  GLU A O   1 
ATOM   3002 C CB  . GLU A 1 458  ? 130.263 84.875  57.973  1.00 118.63 ? 417  GLU A CB  1 
ATOM   3003 C CG  . GLU A 1 458  ? 131.770 84.908  58.189  1.00 118.63 ? 417  GLU A CG  1 
ATOM   3004 C CD  . GLU A 1 458  ? 132.273 83.841  59.150  1.00 118.63 ? 417  GLU A CD  1 
ATOM   3005 O OE1 . GLU A 1 458  ? 133.295 84.092  59.822  1.00 118.63 ? 417  GLU A OE1 1 
ATOM   3006 O OE2 . GLU A 1 458  ? 131.661 82.758  59.242  1.00 118.63 ? 417  GLU A OE2 1 
ATOM   3007 N N   . ARG A 1 459  ? 127.413 83.514  56.392  1.00 120.46 ? 418  ARG A N   1 
ATOM   3008 C CA  . ARG A 1 459  ? 125.985 83.264  56.579  1.00 120.46 ? 418  ARG A CA  1 
ATOM   3009 C C   . ARG A 1 459  ? 125.353 84.263  57.543  1.00 120.46 ? 418  ARG A C   1 
ATOM   3010 O O   . ARG A 1 459  ? 124.353 83.960  58.198  1.00 120.46 ? 418  ARG A O   1 
ATOM   3011 C CB  . ARG A 1 459  ? 125.724 81.832  57.052  1.00 120.46 ? 418  ARG A CB  1 
ATOM   3012 C CG  . ARG A 1 459  ? 125.281 80.888  55.953  1.00 120.46 ? 418  ARG A CG  1 
ATOM   3013 C CD  . ARG A 1 459  ? 123.851 81.173  55.534  1.00 120.46 ? 418  ARG A CD  1 
ATOM   3014 N NE  . ARG A 1 459  ? 122.888 80.689  56.516  1.00 120.46 ? 418  ARG A NE  1 
ATOM   3015 C CZ  . ARG A 1 459  ? 122.455 79.437  56.587  1.00 120.46 ? 418  ARG A CZ  1 
ATOM   3016 N NH1 . ARG A 1 459  ? 122.882 78.511  55.745  1.00 120.46 ? 418  ARG A NH1 1 
ATOM   3017 N NH2 . ARG A 1 459  ? 121.574 79.107  57.525  1.00 120.46 ? 418  ARG A NH2 1 
ATOM   3018 N N   . PHE A 1 460  ? 125.933 85.461  57.644  1.00 111.38 ? 419  PHE A N   1 
ATOM   3019 C CA  . PHE A 1 460  ? 125.302 86.513  58.433  1.00 111.38 ? 419  PHE A CA  1 
ATOM   3020 C C   . PHE A 1 460  ? 123.954 86.897  57.841  1.00 111.38 ? 419  PHE A C   1 
ATOM   3021 O O   . PHE A 1 460  ? 122.976 87.090  58.570  1.00 111.38 ? 419  PHE A O   1 
ATOM   3022 C CB  . PHE A 1 460  ? 126.218 87.734  58.519  1.00 111.38 ? 419  PHE A CB  1 
ATOM   3023 C CG  . PHE A 1 460  ? 127.387 87.555  59.444  1.00 111.38 ? 419  PHE A CG  1 
ATOM   3024 C CD1 . PHE A 1 460  ? 127.557 86.380  60.153  1.00 111.38 ? 419  PHE A CD1 1 
ATOM   3025 C CD2 . PHE A 1 460  ? 128.313 88.567  59.609  1.00 111.38 ? 419  PHE A CD2 1 
ATOM   3026 C CE1 . PHE A 1 460  ? 128.629 86.218  61.003  1.00 111.38 ? 419  PHE A CE1 1 
ATOM   3027 C CE2 . PHE A 1 460  ? 129.386 88.409  60.458  1.00 111.38 ? 419  PHE A CE2 1 
ATOM   3028 C CZ  . PHE A 1 460  ? 129.544 87.234  61.155  1.00 111.38 ? 419  PHE A CZ  1 
ATOM   3029 N N   . TYR A 1 461  ? 123.887 87.014  56.521  1.00 119.91 ? 420  TYR A N   1 
ATOM   3030 C CA  . TYR A 1 461  ? 122.647 87.219  55.790  1.00 119.91 ? 420  TYR A CA  1 
ATOM   3031 C C   . TYR A 1 461  ? 122.445 86.051  54.828  1.00 119.91 ? 420  TYR A C   1 
ATOM   3032 O O   . TYR A 1 461  ? 123.194 85.071  54.842  1.00 119.91 ? 420  TYR A O   1 
ATOM   3033 C CB  . TYR A 1 461  ? 122.666 88.559  55.052  1.00 119.91 ? 420  TYR A CB  1 
ATOM   3034 C CG  . TYR A 1 461  ? 123.226 89.707  55.858  1.00 119.91 ? 420  TYR A CG  1 
ATOM   3035 C CD1 . TYR A 1 461  ? 122.467 90.326  56.839  1.00 119.91 ? 420  TYR A CD1 1 
ATOM   3036 C CD2 . TYR A 1 461  ? 124.511 90.175  55.630  1.00 119.91 ? 420  TYR A CD2 1 
ATOM   3037 C CE1 . TYR A 1 461  ? 122.975 91.379  57.575  1.00 119.91 ? 420  TYR A CE1 1 
ATOM   3038 C CE2 . TYR A 1 461  ? 125.027 91.226  56.361  1.00 119.91 ? 420  TYR A CE2 1 
ATOM   3039 C CZ  . TYR A 1 461  ? 124.255 91.823  57.331  1.00 119.91 ? 420  TYR A CZ  1 
ATOM   3040 O OH  . TYR A 1 461  ? 124.768 92.869  58.060  1.00 119.91 ? 420  TYR A OH  1 
ATOM   3041 N N   . ASP A 1 462  ? 121.422 86.161  53.987  1.00 132.50 ? 421  ASP A N   1 
ATOM   3042 C CA  . ASP A 1 462  ? 121.146 85.152  52.983  1.00 132.50 ? 421  ASP A CA  1 
ATOM   3043 C C   . ASP A 1 462  ? 120.943 85.815  51.629  1.00 132.50 ? 421  ASP A C   1 
ATOM   3044 O O   . ASP A 1 462  ? 120.363 86.905  51.550  1.00 132.50 ? 421  ASP A O   1 
ATOM   3045 C CB  . ASP A 1 462  ? 119.901 84.332  53.348  1.00 132.50 ? 421  ASP A CB  1 
ATOM   3046 C CG  . ASP A 1 462  ? 120.228 83.129  54.206  1.00 132.50 ? 421  ASP A CG  1 
ATOM   3047 O OD1 . ASP A 1 462  ? 121.354 82.605  54.089  1.00 132.50 ? 421  ASP A OD1 1 
ATOM   3048 O OD2 . ASP A 1 462  ? 119.359 82.706  54.998  1.00 132.50 ? 421  ASP A OD2 1 
ATOM   3049 N N   . PRO A 1 463  ? 121.408 85.190  50.552  1.00 142.93 ? 422  PRO A N   1 
ATOM   3050 C CA  . PRO A 1 463  ? 121.168 85.748  49.220  1.00 142.93 ? 422  PRO A CA  1 
ATOM   3051 C C   . PRO A 1 463  ? 119.698 85.657  48.849  1.00 142.93 ? 422  PRO A C   1 
ATOM   3052 O O   . PRO A 1 463  ? 118.956 84.799  49.330  1.00 142.93 ? 422  PRO A O   1 
ATOM   3053 C CB  . PRO A 1 463  ? 122.028 84.870  48.307  1.00 142.93 ? 422  PRO A CB  1 
ATOM   3054 C CG  . PRO A 1 463  ? 122.123 83.575  49.027  1.00 142.93 ? 422  PRO A CG  1 
ATOM   3055 C CD  . PRO A 1 463  ? 122.123 83.905  50.494  1.00 142.93 ? 422  PRO A CD  1 
ATOM   3056 N N   . ASN A 1 464  ? 119.281 86.565  47.971  1.00 154.59 ? 423  ASN A N   1 
ATOM   3057 C CA  . ASN A 1 464  ? 117.898 86.586  47.525  1.00 154.59 ? 423  ASN A CA  1 
ATOM   3058 C C   . ASN A 1 464  ? 117.616 85.366  46.647  1.00 154.59 ? 423  ASN A C   1 
ATOM   3059 O O   . ASN A 1 464  ? 118.467 84.494  46.448  1.00 154.59 ? 423  ASN A O   1 
ATOM   3060 C CB  . ASN A 1 464  ? 117.599 87.889  46.789  1.00 154.59 ? 423  ASN A CB  1 
ATOM   3061 C CG  . ASN A 1 464  ? 117.412 89.057  47.736  1.00 154.59 ? 423  ASN A CG  1 
ATOM   3062 O OD1 . ASN A 1 464  ? 118.059 90.094  47.598  1.00 154.59 ? 423  ASN A OD1 1 
ATOM   3063 N ND2 . ASN A 1 464  ? 116.527 88.891  48.711  1.00 154.59 ? 423  ASN A ND2 1 
ATOM   3064 N N   . SER A 1 465  ? 116.396 85.306  46.110  1.00 165.12 ? 424  SER A N   1 
ATOM   3065 C CA  . SER A 1 465  ? 115.948 84.108  45.411  1.00 165.12 ? 424  SER A CA  1 
ATOM   3066 C C   . SER A 1 465  ? 116.778 83.862  44.159  1.00 165.12 ? 424  SER A C   1 
ATOM   3067 O O   . SER A 1 465  ? 116.599 84.533  43.138  1.00 165.12 ? 424  SER A O   1 
ATOM   3068 C CB  . SER A 1 465  ? 114.465 84.223  45.051  1.00 165.12 ? 424  SER A CB  1 
ATOM   3069 O OG  . SER A 1 465  ? 113.671 84.398  46.212  1.00 165.12 ? 424  SER A OG  1 
ATOM   3070 N N   . GLY A 1 466  ? 117.672 82.878  44.230  1.00 172.09 ? 425  GLY A N   1 
ATOM   3071 C CA  . GLY A 1 466  ? 118.581 82.572  43.144  1.00 172.09 ? 425  GLY A CA  1 
ATOM   3072 C C   . GLY A 1 466  ? 119.217 81.207  43.306  1.00 172.09 ? 425  GLY A C   1 
ATOM   3073 O O   . GLY A 1 466  ? 118.544 80.247  43.693  1.00 172.09 ? 425  GLY A O   1 
ATOM   3074 N N   . GLN A 1 467  ? 120.515 81.105  43.017  1.00 172.05 ? 426  GLN A N   1 
ATOM   3075 C CA  . GLN A 1 467  ? 121.223 79.827  43.133  1.00 172.05 ? 426  GLN A CA  1 
ATOM   3076 C C   . GLN A 1 467  ? 122.654 80.123  43.588  1.00 172.05 ? 426  GLN A C   1 
ATOM   3077 O O   . GLN A 1 467  ? 123.539 80.374  42.769  1.00 172.05 ? 426  GLN A O   1 
ATOM   3078 C CB  . GLN A 1 467  ? 121.194 79.065  41.817  1.00 172.05 ? 426  GLN A CB  1 
ATOM   3079 C CG  . GLN A 1 467  ? 121.738 77.653  41.898  1.00 172.05 ? 426  GLN A CG  1 
ATOM   3080 C CD  . GLN A 1 467  ? 123.178 77.561  41.441  1.00 172.05 ? 426  GLN A CD  1 
ATOM   3081 O OE1 . GLN A 1 467  ? 123.640 78.370  40.635  1.00 172.05 ? 426  GLN A OE1 1 
ATOM   3082 N NE2 . GLN A 1 467  ? 123.897 76.569  41.948  1.00 172.05 ? 426  GLN A NE2 1 
ATOM   3083 N N   . VAL A 1 468  ? 122.866 80.070  44.902  1.00 167.42 ? 427  VAL A N   1 
ATOM   3084 C CA  . VAL A 1 468  ? 124.167 80.312  45.514  1.00 167.42 ? 427  VAL A CA  1 
ATOM   3085 C C   . VAL A 1 468  ? 124.530 79.090  46.342  1.00 167.42 ? 427  VAL A C   1 
ATOM   3086 O O   . VAL A 1 468  ? 123.689 78.570  47.082  1.00 167.42 ? 427  VAL A O   1 
ATOM   3087 C CB  . VAL A 1 468  ? 124.160 81.578  46.392  1.00 167.42 ? 427  VAL A CB  1 
ATOM   3088 C CG1 . VAL A 1 468  ? 125.513 81.774  47.062  1.00 167.42 ? 427  VAL A CG1 1 
ATOM   3089 C CG2 . VAL A 1 468  ? 123.780 82.797  45.568  1.00 167.42 ? 427  VAL A CG2 1 
ATOM   3090 N N   . LEU A 1 469  ? 125.773 78.632  46.219  1.00 164.41 ? 428  LEU A N   1 
ATOM   3091 C CA  . LEU A 1 469  ? 126.211 77.406  46.873  1.00 164.41 ? 428  LEU A CA  1 
ATOM   3092 C C   . LEU A 1 469  ? 127.531 77.638  47.597  1.00 164.41 ? 428  LEU A C   1 
ATOM   3093 O O   . LEU A 1 469  ? 128.087 78.740  47.599  1.00 164.41 ? 428  LEU A O   1 
ATOM   3094 C CB  . LEU A 1 469  ? 126.341 76.259  45.859  1.00 164.41 ? 428  LEU A CB  1 
ATOM   3095 C CG  . LEU A 1 469  ? 127.261 76.465  44.651  1.00 164.41 ? 428  LEU A CG  1 
ATOM   3096 C CD1 . LEU A 1 469  ? 128.689 76.029  44.949  1.00 164.41 ? 428  LEU A CD1 1 
ATOM   3097 C CD2 . LEU A 1 469  ? 126.721 75.724  43.441  1.00 164.41 ? 428  LEU A CD2 1 
ATOM   3098 N N   . LEU A 1 470  ? 128.021 76.575  48.235  1.00 163.08 ? 429  LEU A N   1 
ATOM   3099 C CA  . LEU A 1 470  ? 129.353 76.538  48.827  1.00 163.08 ? 429  LEU A CA  1 
ATOM   3100 C C   . LEU A 1 470  ? 129.886 75.123  48.682  1.00 163.08 ? 429  LEU A C   1 
ATOM   3101 O O   . LEU A 1 470  ? 129.259 74.174  49.161  1.00 163.08 ? 429  LEU A O   1 
ATOM   3102 C CB  . LEU A 1 470  ? 129.335 76.953  50.301  1.00 163.08 ? 429  LEU A CB  1 
ATOM   3103 C CG  . LEU A 1 470  ? 130.692 77.056  51.008  1.00 163.08 ? 429  LEU A CG  1 
ATOM   3104 C CD1 . LEU A 1 470  ? 130.695 78.219  51.985  1.00 163.08 ? 429  LEU A CD1 1 
ATOM   3105 C CD2 . LEU A 1 470  ? 131.053 75.760  51.728  1.00 163.08 ? 429  LEU A CD2 1 
ATOM   3106 N N   . ASP A 1 471  ? 131.032 74.984  48.017  1.00 164.85 ? 430  ASP A N   1 
ATOM   3107 C CA  . ASP A 1 471  ? 131.706 73.708  47.800  1.00 164.85 ? 430  ASP A CA  1 
ATOM   3108 C C   . ASP A 1 471  ? 130.852 72.711  47.023  1.00 164.85 ? 430  ASP A C   1 
ATOM   3109 O O   . ASP A 1 471  ? 131.229 71.539  46.906  1.00 164.85 ? 430  ASP A O   1 
ATOM   3110 C CB  . ASP A 1 471  ? 132.154 73.082  49.128  1.00 164.85 ? 430  ASP A CB  1 
ATOM   3111 C CG  . ASP A 1 471  ? 133.355 72.179  48.969  1.00 164.85 ? 430  ASP A CG  1 
ATOM   3112 O OD1 . ASP A 1 471  ? 134.043 72.288  47.934  1.00 164.85 ? 430  ASP A OD1 1 
ATOM   3113 O OD2 . ASP A 1 471  ? 133.607 71.359  49.874  1.00 164.85 ? 430  ASP A OD2 1 
ATOM   3114 N N   . GLY A 1 472  ? 129.719 73.145  46.479  1.00 164.86 ? 431  GLY A N   1 
ATOM   3115 C CA  . GLY A 1 472  ? 128.807 72.253  45.798  1.00 164.86 ? 431  GLY A CA  1 
ATOM   3116 C C   . GLY A 1 472  ? 127.708 71.672  46.657  1.00 164.86 ? 431  GLY A C   1 
ATOM   3117 O O   . GLY A 1 472  ? 127.002 70.768  46.197  1.00 164.86 ? 431  GLY A O   1 
ATOM   3118 N N   . GLN A 1 473  ? 127.537 72.157  47.889  1.00 161.37 ? 432  GLN A N   1 
ATOM   3119 C CA  . GLN A 1 473  ? 126.507 71.647  48.787  1.00 161.37 ? 432  GLN A CA  1 
ATOM   3120 C C   . GLN A 1 473  ? 125.686 72.778  49.394  1.00 161.37 ? 432  GLN A C   1 
ATOM   3121 O O   . GLN A 1 473  ? 125.132 72.631  50.486  1.00 161.37 ? 432  GLN A O   1 
ATOM   3122 C CB  . GLN A 1 473  ? 127.116 70.784  49.892  1.00 161.37 ? 432  GLN A CB  1 
ATOM   3123 C CG  . GLN A 1 473  ? 127.739 69.488  49.402  1.00 161.37 ? 432  GLN A CG  1 
ATOM   3124 C CD  . GLN A 1 473  ? 129.139 69.682  48.863  1.00 161.37 ? 432  GLN A CD  1 
ATOM   3125 O OE1 . GLN A 1 473  ? 129.781 70.698  49.129  1.00 161.37 ? 432  GLN A OE1 1 
ATOM   3126 N NE2 . GLN A 1 473  ? 129.622 68.709  48.101  1.00 161.37 ? 432  GLN A NE2 1 
ATOM   3127 N N   . ASP A 1 474  ? 125.611 73.916  48.697  1.00 156.47 ? 433  ASP A N   1 
ATOM   3128 C CA  . ASP A 1 474  ? 124.786 75.053  49.098  1.00 156.47 ? 433  ASP A CA  1 
ATOM   3129 C C   . ASP A 1 474  ? 125.237 75.583  50.457  1.00 156.47 ? 433  ASP A C   1 
ATOM   3130 O O   . ASP A 1 474  ? 126.280 75.170  50.971  1.00 156.47 ? 433  ASP A O   1 
ATOM   3131 C CB  . ASP A 1 474  ? 123.305 74.640  49.104  1.00 156.47 ? 433  ASP A CB  1 
ATOM   3132 C CG  . ASP A 1 474  ? 122.362 75.806  49.330  1.00 156.47 ? 433  ASP A CG  1 
ATOM   3133 O OD1 . ASP A 1 474  ? 122.170 76.607  48.393  1.00 156.47 ? 433  ASP A OD1 1 
ATOM   3134 O OD2 . ASP A 1 474  ? 121.817 75.924  50.447  1.00 156.47 ? 433  ASP A OD2 1 
ATOM   3135 N N   . LEU A 1 475  ? 124.484 76.511  51.039  1.00 149.41 ? 434  LEU A N   1 
ATOM   3136 C CA  . LEU A 1 475  ? 124.739 77.007  52.385  1.00 149.41 ? 434  LEU A CA  1 
ATOM   3137 C C   . LEU A 1 475  ? 123.706 76.537  53.393  1.00 149.41 ? 434  LEU A C   1 
ATOM   3138 O O   . LEU A 1 475  ? 124.064 76.185  54.518  1.00 149.41 ? 434  LEU A O   1 
ATOM   3139 C CB  . LEU A 1 475  ? 124.777 78.540  52.399  1.00 149.41 ? 434  LEU A CB  1 
ATOM   3140 C CG  . LEU A 1 475  ? 126.060 79.280  52.007  1.00 149.41 ? 434  LEU A CG  1 
ATOM   3141 C CD1 . LEU A 1 475  ? 127.198 78.952  52.966  1.00 149.41 ? 434  LEU A CD1 1 
ATOM   3142 C CD2 . LEU A 1 475  ? 126.458 79.020  50.563  1.00 149.41 ? 434  LEU A CD2 1 
ATOM   3143 N N   . LYS A 1 476  ? 122.428 76.524  53.011  1.00 147.54 ? 435  LYS A N   1 
ATOM   3144 C CA  . LYS A 1 476  ? 121.372 76.116  53.929  1.00 147.54 ? 435  LYS A CA  1 
ATOM   3145 C C   . LYS A 1 476  ? 121.419 74.627  54.239  1.00 147.54 ? 435  LYS A C   1 
ATOM   3146 O O   . LYS A 1 476  ? 120.841 74.197  55.242  1.00 147.54 ? 435  LYS A O   1 
ATOM   3147 C CB  . LYS A 1 476  ? 119.998 76.475  53.355  1.00 147.54 ? 435  LYS A CB  1 
ATOM   3148 C CG  . LYS A 1 476  ? 119.645 77.958  53.391  1.00 147.54 ? 435  LYS A CG  1 
ATOM   3149 C CD  . LYS A 1 476  ? 120.372 78.753  52.319  1.00 147.54 ? 435  LYS A CD  1 
ATOM   3150 C CE  . LYS A 1 476  ? 119.669 80.066  52.032  1.00 147.54 ? 435  LYS A CE  1 
ATOM   3151 N NZ  . LYS A 1 476  ? 120.613 81.095  51.520  1.00 147.54 ? 435  LYS A NZ  1 
ATOM   3152 N N   . THR A 1 477  ? 122.092 73.834  53.407  1.00 151.76 ? 436  THR A N   1 
ATOM   3153 C CA  . THR A 1 477  ? 122.150 72.390  53.574  1.00 151.76 ? 436  THR A CA  1 
ATOM   3154 C C   . THR A 1 477  ? 123.452 71.930  54.219  1.00 151.76 ? 436  THR A C   1 
ATOM   3155 O O   . THR A 1 477  ? 123.832 70.764  54.070  1.00 151.76 ? 436  THR A O   1 
ATOM   3156 C CB  . THR A 1 477  ? 121.958 71.695  52.226  1.00 151.76 ? 436  THR A CB  1 
ATOM   3157 O OG1 . THR A 1 477  ? 123.185 71.737  51.487  1.00 151.76 ? 436  THR A OG1 1 
ATOM   3158 C CG2 . THR A 1 477  ? 120.866 72.388  51.425  1.00 151.76 ? 436  THR A CG2 1 
ATOM   3159 N N   . LEU A 1 478  ? 124.148 72.823  54.922  1.00 149.44 ? 437  LEU A N   1 
ATOM   3160 C CA  . LEU A 1 478  ? 125.382 72.468  55.609  1.00 149.44 ? 437  LEU A CA  1 
ATOM   3161 C C   . LEU A 1 478  ? 125.417 72.964  57.049  1.00 149.44 ? 437  LEU A C   1 
ATOM   3162 O O   . LEU A 1 478  ? 126.497 72.988  57.651  1.00 149.44 ? 437  LEU A O   1 
ATOM   3163 C CB  . LEU A 1 478  ? 126.600 73.010  54.852  1.00 149.44 ? 437  LEU A CB  1 
ATOM   3164 C CG  . LEU A 1 478  ? 126.868 72.418  53.470  1.00 149.44 ? 437  LEU A CG  1 
ATOM   3165 C CD1 . LEU A 1 478  ? 128.013 73.150  52.795  1.00 149.44 ? 437  LEU A CD1 1 
ATOM   3166 C CD2 . LEU A 1 478  ? 127.173 70.935  53.582  1.00 149.44 ? 437  LEU A CD2 1 
ATOM   3167 N N   . LYS A 1 479  ? 124.274 73.363  57.610  1.00 142.14 ? 438  LYS A N   1 
ATOM   3168 C CA  . LYS A 1 479  ? 124.209 73.957  58.940  1.00 142.14 ? 438  LYS A CA  1 
ATOM   3169 C C   . LYS A 1 479  ? 125.081 75.202  59.025  1.00 142.14 ? 438  LYS A C   1 
ATOM   3170 O O   . LYS A 1 479  ? 125.635 75.655  58.017  1.00 142.14 ? 438  LYS A O   1 
ATOM   3171 C CB  . LYS A 1 479  ? 124.631 72.954  60.019  1.00 142.14 ? 438  LYS A CB  1 
ATOM   3172 C CG  . LYS A 1 479  ? 123.631 71.848  60.278  1.00 142.14 ? 438  LYS A CG  1 
ATOM   3173 C CD  . LYS A 1 479  ? 124.248 70.744  61.118  1.00 142.14 ? 438  LYS A CD  1 
ATOM   3174 C CE  . LYS A 1 479  ? 124.675 71.267  62.479  1.00 142.14 ? 438  LYS A CE  1 
ATOM   3175 N NZ  . LYS A 1 479  ? 124.875 70.164  63.457  1.00 142.14 ? 438  LYS A NZ  1 
ATOM   3176 N N   . LEU A 1 480  ? 125.185 75.783  60.216  1.00 130.40 ? 439  LEU A N   1 
ATOM   3177 C CA  . LEU A 1 480  ? 126.160 76.835  60.449  1.00 130.40 ? 439  LEU A CA  1 
ATOM   3178 C C   . LEU A 1 480  ? 126.855 76.708  61.794  1.00 130.40 ? 439  LEU A C   1 
ATOM   3179 O O   . LEU A 1 480  ? 127.745 77.513  62.083  1.00 130.40 ? 439  LEU A O   1 
ATOM   3180 C CB  . LEU A 1 480  ? 125.507 78.222  60.337  1.00 130.40 ? 439  LEU A CB  1 
ATOM   3181 C CG  . LEU A 1 480  ? 124.668 78.730  61.506  1.00 130.40 ? 439  LEU A CG  1 
ATOM   3182 C CD1 . LEU A 1 480  ? 124.432 80.221  61.358  1.00 130.40 ? 439  LEU A CD1 1 
ATOM   3183 C CD2 . LEU A 1 480  ? 123.351 77.992  61.583  1.00 130.40 ? 439  LEU A CD2 1 
ATOM   3184 N N   . ARG A 1 481  ? 126.483 75.733  62.624  1.00 126.23 ? 440  ARG A N   1 
ATOM   3185 C CA  . ARG A 1 481  ? 127.195 75.532  63.879  1.00 126.23 ? 440  ARG A CA  1 
ATOM   3186 C C   . ARG A 1 481  ? 128.637 75.115  63.629  1.00 126.23 ? 440  ARG A C   1 
ATOM   3187 O O   . ARG A 1 481  ? 129.551 75.578  64.320  1.00 126.23 ? 440  ARG A O   1 
ATOM   3188 C CB  . ARG A 1 481  ? 126.475 74.492  64.737  1.00 126.23 ? 440  ARG A CB  1 
ATOM   3189 C CG  . ARG A 1 481  ? 126.864 74.531  66.205  1.00 126.23 ? 440  ARG A CG  1 
ATOM   3190 C CD  . ARG A 1 481  ? 126.909 73.134  66.803  1.00 126.23 ? 440  ARG A CD  1 
ATOM   3191 N NE  . ARG A 1 481  ? 127.814 72.252  66.075  1.00 126.23 ? 440  ARG A NE  1 
ATOM   3192 C CZ  . ARG A 1 481  ? 129.136 72.339  66.103  1.00 126.23 ? 440  ARG A CZ  1 
ATOM   3193 N NH1 . ARG A 1 481  ? 129.755 73.256  66.829  1.00 126.23 ? 440  ARG A NH1 1 
ATOM   3194 N NH2 . ARG A 1 481  ? 129.858 71.481  65.387  1.00 126.23 ? 440  ARG A NH2 1 
ATOM   3195 N N   . TRP A 1 482  ? 128.861 74.244  62.643  1.00 135.72 ? 441  TRP A N   1 
ATOM   3196 C CA  . TRP A 1 482  ? 130.212 73.819  62.303  1.00 135.72 ? 441  TRP A CA  1 
ATOM   3197 C C   . TRP A 1 482  ? 130.728 74.474  61.032  1.00 135.72 ? 441  TRP A C   1 
ATOM   3198 O O   . TRP A 1 482  ? 131.942 74.483  60.810  1.00 135.72 ? 441  TRP A O   1 
ATOM   3199 C CB  . TRP A 1 482  ? 130.271 72.300  62.125  1.00 135.72 ? 441  TRP A CB  1 
ATOM   3200 C CG  . TRP A 1 482  ? 129.421 71.810  61.009  1.00 135.72 ? 441  TRP A CG  1 
ATOM   3201 C CD1 . TRP A 1 482  ? 128.111 71.441  61.069  1.00 135.72 ? 441  TRP A CD1 1 
ATOM   3202 C CD2 . TRP A 1 482  ? 129.835 71.610  59.654  1.00 135.72 ? 441  TRP A CD2 1 
ATOM   3203 N NE1 . TRP A 1 482  ? 127.677 71.039  59.828  1.00 135.72 ? 441  TRP A NE1 1 
ATOM   3204 C CE2 . TRP A 1 482  ? 128.720 71.130  58.943  1.00 135.72 ? 441  TRP A CE2 1 
ATOM   3205 C CE3 . TRP A 1 482  ? 131.041 71.795  58.971  1.00 135.72 ? 441  TRP A CE3 1 
ATOM   3206 C CZ2 . TRP A 1 482  ? 128.773 70.834  57.584  1.00 135.72 ? 441  TRP A CZ2 1 
ATOM   3207 C CZ3 . TRP A 1 482  ? 131.092 71.502  57.625  1.00 135.72 ? 441  TRP A CZ3 1 
ATOM   3208 C CH2 . TRP A 1 482  ? 129.967 71.025  56.944  1.00 135.72 ? 441  TRP A CH2 1 
ATOM   3209 N N   . LEU A 1 483  ? 129.834 74.997  60.189  1.00 126.43 ? 442  LEU A N   1 
ATOM   3210 C CA  . LEU A 1 483  ? 130.275 75.750  59.020  1.00 126.43 ? 442  LEU A CA  1 
ATOM   3211 C C   . LEU A 1 483  ? 131.095 76.961  59.433  1.00 126.43 ? 442  LEU A C   1 
ATOM   3212 O O   . LEU A 1 483  ? 132.137 77.250  58.834  1.00 126.43 ? 442  LEU A O   1 
ATOM   3213 C CB  . LEU A 1 483  ? 129.072 76.187  58.191  1.00 126.43 ? 442  LEU A CB  1 
ATOM   3214 C CG  . LEU A 1 483  ? 129.411 76.935  56.903  1.00 126.43 ? 442  LEU A CG  1 
ATOM   3215 C CD1 . LEU A 1 483  ? 130.200 76.046  55.959  1.00 126.43 ? 442  LEU A CD1 1 
ATOM   3216 C CD2 . LEU A 1 483  ? 128.149 77.452  56.238  1.00 126.43 ? 442  LEU A CD2 1 
ATOM   3217 N N   . ARG A 1 484  ? 130.639 77.681  60.456  1.00 117.37 ? 443  ARG A N   1 
ATOM   3218 C CA  . ARG A 1 484  ? 131.413 78.796  60.979  1.00 117.37 ? 443  ARG A CA  1 
ATOM   3219 C C   . ARG A 1 484  ? 132.678 78.327  61.681  1.00 117.37 ? 443  ARG A C   1 
ATOM   3220 O O   . ARG A 1 484  ? 133.625 79.109  61.811  1.00 117.37 ? 443  ARG A O   1 
ATOM   3221 C CB  . ARG A 1 484  ? 130.547 79.625  61.923  1.00 117.37 ? 443  ARG A CB  1 
ATOM   3222 C CG  . ARG A 1 484  ? 129.369 80.277  61.225  1.00 117.37 ? 443  ARG A CG  1 
ATOM   3223 C CD  . ARG A 1 484  ? 128.480 81.023  62.195  1.00 117.37 ? 443  ARG A CD  1 
ATOM   3224 N NE  . ARG A 1 484  ? 127.712 82.061  61.523  1.00 117.37 ? 443  ARG A NE  1 
ATOM   3225 C CZ  . ARG A 1 484  ? 126.733 82.752  62.088  1.00 117.37 ? 443  ARG A CZ  1 
ATOM   3226 N NH1 . ARG A 1 484  ? 126.370 82.538  63.341  1.00 117.37 ? 443  ARG A NH1 1 
ATOM   3227 N NH2 . ARG A 1 484  ? 126.099 83.679  61.376  1.00 117.37 ? 443  ARG A NH2 1 
ATOM   3228 N N   . GLN A 1 485  ? 132.714 77.075  62.137  1.00 122.08 ? 444  GLN A N   1 
ATOM   3229 C CA  . GLN A 1 485  ? 133.946 76.529  62.695  1.00 122.08 ? 444  GLN A CA  1 
ATOM   3230 C C   . GLN A 1 485  ? 135.023 76.403  61.624  1.00 122.08 ? 444  GLN A C   1 
ATOM   3231 O O   . GLN A 1 485  ? 136.204 76.647  61.893  1.00 122.08 ? 444  GLN A O   1 
ATOM   3232 C CB  . GLN A 1 485  ? 133.672 75.174  63.343  1.00 122.08 ? 444  GLN A CB  1 
ATOM   3233 C CG  . GLN A 1 485  ? 134.808 74.648  64.198  1.00 122.08 ? 444  GLN A CG  1 
ATOM   3234 C CD  . GLN A 1 485  ? 134.319 73.744  65.310  1.00 122.08 ? 444  GLN A CD  1 
ATOM   3235 O OE1 . GLN A 1 485  ? 133.116 73.551  65.485  1.00 122.08 ? 444  GLN A OE1 1 
ATOM   3236 N NE2 . GLN A 1 485  ? 135.251 73.183  66.072  1.00 122.08 ? 444  GLN A NE2 1 
ATOM   3237 N N   . GLN A 1 486  ? 134.635 76.012  60.409  1.00 123.28 ? 445  GLN A N   1 
ATOM   3238 C CA  . GLN A 1 486  ? 135.601 75.898  59.320  1.00 123.28 ? 445  GLN A CA  1 
ATOM   3239 C C   . GLN A 1 486  ? 136.174 77.257  58.940  1.00 123.28 ? 445  GLN A C   1 
ATOM   3240 O O   . GLN A 1 486  ? 137.374 77.377  58.670  1.00 123.28 ? 445  GLN A O   1 
ATOM   3241 C CB  . GLN A 1 486  ? 134.949 75.240  58.105  1.00 123.28 ? 445  GLN A CB  1 
ATOM   3242 C CG  . GLN A 1 486  ? 134.065 74.050  58.426  1.00 123.28 ? 445  GLN A CG  1 
ATOM   3243 C CD  . GLN A 1 486  ? 134.752 73.032  59.309  1.00 123.28 ? 445  GLN A CD  1 
ATOM   3244 O OE1 . GLN A 1 486  ? 134.195 72.589  60.313  1.00 123.28 ? 445  GLN A OE1 1 
ATOM   3245 N NE2 . GLN A 1 486  ? 135.970 72.651  58.940  1.00 123.28 ? 445  GLN A NE2 1 
ATOM   3246 N N   . ILE A 1 487  ? 135.338 78.285  58.918  1.00 118.28 ? 446  ILE A N   1 
ATOM   3247 C CA  . ILE A 1 487  ? 135.745 79.600  58.440  1.00 118.28 ? 446  ILE A CA  1 
ATOM   3248 C C   . ILE A 1 487  ? 136.424 80.369  59.563  1.00 118.28 ? 446  ILE A C   1 
ATOM   3249 O O   . ILE A 1 487  ? 135.971 80.354  60.713  1.00 118.28 ? 446  ILE A O   1 
ATOM   3250 C CB  . ILE A 1 487  ? 134.530 80.367  57.895  1.00 118.28 ? 446  ILE A CB  1 
ATOM   3251 C CG1 . ILE A 1 487  ? 133.714 79.466  56.968  1.00 118.28 ? 446  ILE A CG1 1 
ATOM   3252 C CG2 . ILE A 1 487  ? 134.971 81.626  57.175  1.00 118.28 ? 446  ILE A CG2 1 
ATOM   3253 C CD1 . ILE A 1 487  ? 132.351 80.014  56.632  1.00 118.28 ? 446  ILE A CD1 1 
ATOM   3254 N N   . GLY A 1 488  ? 137.520 81.044  59.231  1.00 118.12 ? 447  GLY A N   1 
ATOM   3255 C CA  . GLY A 1 488  ? 138.197 81.905  60.180  1.00 118.12 ? 447  GLY A CA  1 
ATOM   3256 C C   . GLY A 1 488  ? 138.118 83.357  59.759  1.00 118.12 ? 447  GLY A C   1 
ATOM   3257 O O   . GLY A 1 488  ? 138.409 83.687  58.608  1.00 118.12 ? 447  GLY A O   1 
ATOM   3258 N N   . LEU A 1 489  ? 137.724 84.234  60.675  1.00 113.04 ? 448  LEU A N   1 
ATOM   3259 C CA  . LEU A 1 489  ? 137.483 85.633  60.360  1.00 113.04 ? 448  LEU A CA  1 
ATOM   3260 C C   . LEU A 1 489  ? 138.416 86.532  61.160  1.00 113.04 ? 448  LEU A C   1 
ATOM   3261 O O   . LEU A 1 489  ? 138.601 86.339  62.365  1.00 113.04 ? 448  LEU A O   1 
ATOM   3262 C CB  . LEU A 1 489  ? 136.029 86.012  60.647  1.00 113.04 ? 448  LEU A CB  1 
ATOM   3263 C CG  . LEU A 1 489  ? 135.692 87.504  60.610  1.00 113.04 ? 448  LEU A CG  1 
ATOM   3264 C CD1 . LEU A 1 489  ? 135.758 88.035  59.190  1.00 113.04 ? 448  LEU A CD1 1 
ATOM   3265 C CD2 . LEU A 1 489  ? 134.327 87.765  61.219  1.00 113.04 ? 448  LEU A CD2 1 
ATOM   3266 N N   . VAL A 1 490  ? 139.006 87.509  60.476  1.00 122.73 ? 449  VAL A N   1 
ATOM   3267 C CA  . VAL A 1 490  ? 139.775 88.578  61.103  1.00 122.73 ? 449  VAL A CA  1 
ATOM   3268 C C   . VAL A 1 490  ? 139.173 89.901  60.652  1.00 122.73 ? 449  VAL A C   1 
ATOM   3269 O O   . VAL A 1 490  ? 139.092 90.171  59.449  1.00 122.73 ? 449  VAL A O   1 
ATOM   3270 C CB  . VAL A 1 490  ? 141.267 88.500  60.738  1.00 122.73 ? 449  VAL A CB  1 
ATOM   3271 C CG1 . VAL A 1 490  ? 142.053 89.539  61.516  1.00 122.73 ? 449  VAL A CG1 1 
ATOM   3272 C CG2 . VAL A 1 490  ? 141.807 87.105  61.004  1.00 122.73 ? 449  VAL A CG2 1 
ATOM   3273 N N   . SER A 1 491  ? 138.757 90.720  61.611  1.00 129.19 ? 450  SER A N   1 
ATOM   3274 C CA  . SER A 1 491  ? 137.991 91.919  61.312  1.00 129.19 ? 450  SER A CA  1 
ATOM   3275 C C   . SER A 1 491  ? 138.903 93.135  61.157  1.00 129.19 ? 450  SER A C   1 
ATOM   3276 O O   . SER A 1 491  ? 140.114 93.076  61.383  1.00 129.19 ? 450  SER A O   1 
ATOM   3277 C CB  . SER A 1 491  ? 136.951 92.173  62.403  1.00 129.19 ? 450  SER A CB  1 
ATOM   3278 O OG  . SER A 1 491  ? 137.569 92.468  63.643  1.00 129.19 ? 450  SER A OG  1 
ATOM   3279 N N   . GLN A 1 492  ? 138.292 94.252  60.747  1.00 138.62 ? 451  GLN A N   1 
ATOM   3280 C CA  . GLN A 1 492  ? 139.030 95.503  60.586  1.00 138.62 ? 451  GLN A CA  1 
ATOM   3281 C C   . GLN A 1 492  ? 139.713 95.902  61.887  1.00 138.62 ? 451  GLN A C   1 
ATOM   3282 O O   . GLN A 1 492  ? 140.925 96.142  61.921  1.00 138.62 ? 451  GLN A O   1 
ATOM   3283 C CB  . GLN A 1 492  ? 138.080 96.611  60.129  1.00 138.62 ? 451  GLN A CB  1 
ATOM   3284 C CG  . GLN A 1 492  ? 137.468 96.422  58.749  1.00 138.62 ? 451  GLN A CG  1 
ATOM   3285 C CD  . GLN A 1 492  ? 138.428 96.761  57.629  1.00 138.62 ? 451  GLN A CD  1 
ATOM   3286 O OE1 . GLN A 1 492  ? 139.220 97.699  57.738  1.00 138.62 ? 451  GLN A OE1 1 
ATOM   3287 N NE2 . GLN A 1 492  ? 138.355 96.011  56.537  1.00 138.62 ? 451  GLN A NE2 1 
ATOM   3288 N N   . GLU A 1 493  ? 138.945 95.974  62.970  1.00 129.97 ? 452  GLU A N   1 
ATOM   3289 C CA  . GLU A 1 493  ? 139.474 96.233  64.298  1.00 129.97 ? 452  GLU A CA  1 
ATOM   3290 C C   . GLU A 1 493  ? 139.252 94.999  65.153  1.00 129.97 ? 452  GLU A C   1 
ATOM   3291 O O   . GLU A 1 493  ? 138.100 94.561  65.298  1.00 129.97 ? 452  GLU A O   1 
ATOM   3292 C CB  . GLU A 1 493  ? 138.800 97.448  64.932  1.00 129.97 ? 452  GLU A CB  1 
ATOM   3293 C CG  . GLU A 1 493  ? 138.950 98.730  64.133  1.00 129.97 ? 452  GLU A CG  1 
ATOM   3294 C CD  . GLU A 1 493  ? 137.653 99.508  64.037  1.00 129.97 ? 452  GLU A CD  1 
ATOM   3295 O OE1 . GLU A 1 493  ? 136.687 99.144  64.738  1.00 129.97 ? 452  GLU A OE1 1 
ATOM   3296 O OE2 . GLU A 1 493  ? 137.602 100.486 63.262  1.00 129.97 ? 452  GLU A OE2 1 
ATOM   3297 N N   . PRO A 1 494  ? 140.300 94.398  65.710  1.00 127.65 ? 453  PRO A N   1 
ATOM   3298 C CA  . PRO A 1 494  ? 140.113 93.171  66.492  1.00 127.65 ? 453  PRO A CA  1 
ATOM   3299 C C   . PRO A 1 494  ? 139.180 93.406  67.669  1.00 127.65 ? 453  PRO A C   1 
ATOM   3300 O O   . PRO A 1 494  ? 139.204 94.461  68.305  1.00 127.65 ? 453  PRO A O   1 
ATOM   3301 C CB  . PRO A 1 494  ? 141.531 92.819  66.958  1.00 127.65 ? 453  PRO A CB  1 
ATOM   3302 C CG  . PRO A 1 494  ? 142.340 94.055  66.753  1.00 127.65 ? 453  PRO A CG  1 
ATOM   3303 C CD  . PRO A 1 494  ? 141.710 94.804  65.630  1.00 127.65 ? 453  PRO A CD  1 
ATOM   3304 N N   . ALA A 1 495  ? 138.346 92.409  67.944  1.00 112.57 ? 454  ALA A N   1 
ATOM   3305 C CA  . ALA A 1 495  ? 137.363 92.476  69.017  1.00 112.57 ? 454  ALA A CA  1 
ATOM   3306 C C   . ALA A 1 495  ? 137.860 91.628  70.179  1.00 112.57 ? 454  ALA A C   1 
ATOM   3307 O O   . ALA A 1 495  ? 137.886 90.397  70.092  1.00 112.57 ? 454  ALA A O   1 
ATOM   3308 C CB  . ALA A 1 495  ? 135.996 91.998  68.533  1.00 112.57 ? 454  ALA A CB  1 
ATOM   3309 N N   . LEU A 1 496  ? 138.254 92.287  71.262  1.00 111.88 ? 455  LEU A N   1 
ATOM   3310 C CA  . LEU A 1 496  ? 138.724 91.617  72.464  1.00 111.88 ? 455  LEU A CA  1 
ATOM   3311 C C   . LEU A 1 496  ? 137.726 91.841  73.591  1.00 111.88 ? 455  LEU A C   1 
ATOM   3312 O O   . LEU A 1 496  ? 137.169 92.933  73.732  1.00 111.88 ? 455  LEU A O   1 
ATOM   3313 C CB  . LEU A 1 496  ? 140.110 92.119  72.879  1.00 111.88 ? 455  LEU A CB  1 
ATOM   3314 C CG  . LEU A 1 496  ? 141.328 91.502  72.187  1.00 111.88 ? 455  LEU A CG  1 
ATOM   3315 C CD1 . LEU A 1 496  ? 141.421 90.023  72.514  1.00 111.88 ? 455  LEU A CD1 1 
ATOM   3316 C CD2 . LEU A 1 496  ? 141.310 91.717  70.683  1.00 111.88 ? 455  LEU A CD2 1 
ATOM   3317 N N   . PHE A 1 497  ? 137.505 90.802  74.386  1.00 101.37 ? 456  PHE A N   1 
ATOM   3318 C CA  . PHE A 1 497  ? 136.503 90.827  75.435  1.00 101.37 ? 456  PHE A CA  1 
ATOM   3319 C C   . PHE A 1 497  ? 137.167 91.033  76.792  1.00 101.37 ? 456  PHE A C   1 
ATOM   3320 O O   . PHE A 1 497  ? 138.390 90.983  76.935  1.00 101.37 ? 456  PHE A O   1 
ATOM   3321 C CB  . PHE A 1 497  ? 135.673 89.545  75.387  1.00 101.37 ? 456  PHE A CB  1 
ATOM   3322 C CG  . PHE A 1 497  ? 135.001 89.320  74.066  1.00 101.37 ? 456  PHE A CG  1 
ATOM   3323 C CD1 . PHE A 1 497  ? 133.977 90.150  73.649  1.00 101.37 ? 456  PHE A CD1 1 
ATOM   3324 C CD2 . PHE A 1 497  ? 135.412 88.300  73.229  1.00 101.37 ? 456  PHE A CD2 1 
ATOM   3325 C CE1 . PHE A 1 497  ? 133.364 89.954  72.431  1.00 101.37 ? 456  PHE A CE1 1 
ATOM   3326 C CE2 . PHE A 1 497  ? 134.802 88.104  72.008  1.00 101.37 ? 456  PHE A CE2 1 
ATOM   3327 C CZ  . PHE A 1 497  ? 133.778 88.930  71.609  1.00 101.37 ? 456  PHE A CZ  1 
ATOM   3328 N N   . ALA A 1 498  ? 136.334 91.264  77.808  1.00 110.84 ? 457  ALA A N   1 
ATOM   3329 C CA  . ALA A 1 498  ? 136.829 91.659  79.120  1.00 110.84 ? 457  ALA A CA  1 
ATOM   3330 C C   . ALA A 1 498  ? 137.581 90.547  79.835  1.00 110.84 ? 457  ALA A C   1 
ATOM   3331 O O   . ALA A 1 498  ? 138.260 90.822  80.830  1.00 110.84 ? 457  ALA A O   1 
ATOM   3332 C CB  . ALA A 1 498  ? 135.670 92.135  79.992  1.00 110.84 ? 457  ALA A CB  1 
ATOM   3333 N N   . THR A 1 499  ? 137.486 89.308  79.363  1.00 111.74 ? 458  THR A N   1 
ATOM   3334 C CA  . THR A 1 499  ? 138.133 88.203  80.049  1.00 111.74 ? 458  THR A CA  1 
ATOM   3335 C C   . THR A 1 499  ? 139.644 88.259  79.836  1.00 111.74 ? 458  THR A C   1 
ATOM   3336 O O   . THR A 1 499  ? 140.184 89.178  79.216  1.00 111.74 ? 458  THR A O   1 
ATOM   3337 C CB  . THR A 1 499  ? 137.568 86.871  79.565  1.00 111.74 ? 458  THR A CB  1 
ATOM   3338 O OG1 . THR A 1 499  ? 138.137 85.803  80.332  1.00 111.74 ? 458  THR A OG1 1 
ATOM   3339 C CG2 . THR A 1 499  ? 137.891 86.661  78.094  1.00 111.74 ? 458  THR A CG2 1 
ATOM   3340 N N   . SER A 1 500  ? 140.336 87.256  80.366  1.00 120.31 ? 459  SER A N   1 
ATOM   3341 C CA  . SER A 1 500  ? 141.776 87.174  80.192  1.00 120.31 ? 459  SER A CA  1 
ATOM   3342 C C   . SER A 1 500  ? 142.118 86.929  78.728  1.00 120.31 ? 459  SER A C   1 
ATOM   3343 O O   . SER A 1 500  ? 141.323 86.382  77.959  1.00 120.31 ? 459  SER A O   1 
ATOM   3344 C CB  . SER A 1 500  ? 142.359 86.058  81.057  1.00 120.31 ? 459  SER A CB  1 
ATOM   3345 O OG  . SER A 1 500  ? 141.896 84.789  80.631  1.00 120.31 ? 459  SER A OG  1 
ATOM   3346 N N   . ILE A 1 501  ? 143.324 87.352  78.340  1.00 123.10 ? 460  ILE A N   1 
ATOM   3347 C CA  . ILE A 1 501  ? 143.776 87.113  76.973  1.00 123.10 ? 460  ILE A CA  1 
ATOM   3348 C C   . ILE A 1 501  ? 143.859 85.619  76.702  1.00 123.10 ? 460  ILE A C   1 
ATOM   3349 O O   . ILE A 1 501  ? 143.648 85.164  75.573  1.00 123.10 ? 460  ILE A O   1 
ATOM   3350 C CB  . ILE A 1 501  ? 145.121 87.815  76.712  1.00 123.10 ? 460  ILE A CB  1 
ATOM   3351 C CG1 . ILE A 1 501  ? 146.162 87.389  77.743  1.00 123.10 ? 460  ILE A CG1 1 
ATOM   3352 C CG2 . ILE A 1 501  ? 144.943 89.324  76.728  1.00 123.10 ? 460  ILE A CG2 1 
ATOM   3353 C CD1 . ILE A 1 501  ? 147.515 88.023  77.526  1.00 123.10 ? 460  ILE A CD1 1 
ATOM   3354 N N   . LYS A 1 502  ? 144.150 84.830  77.737  1.00 122.00 ? 461  LYS A N   1 
ATOM   3355 C CA  . LYS A 1 502  ? 144.137 83.380  77.589  1.00 122.00 ? 461  LYS A CA  1 
ATOM   3356 C C   . LYS A 1 502  ? 142.758 82.893  77.155  1.00 122.00 ? 461  LYS A C   1 
ATOM   3357 O O   . LYS A 1 502  ? 142.624 82.205  76.139  1.00 122.00 ? 461  LYS A O   1 
ATOM   3358 C CB  . LYS A 1 502  ? 144.582 82.737  78.902  1.00 122.00 ? 461  LYS A CB  1 
ATOM   3359 C CG  . LYS A 1 502  ? 144.952 81.268  78.842  1.00 122.00 ? 461  LYS A CG  1 
ATOM   3360 C CD  . LYS A 1 502  ? 143.821 80.396  79.333  1.00 122.00 ? 461  LYS A CD  1 
ATOM   3361 C CE  . LYS A 1 502  ? 144.281 78.962  79.528  1.00 122.00 ? 461  LYS A CE  1 
ATOM   3362 N NZ  . LYS A 1 502  ? 143.336 78.186  80.376  1.00 122.00 ? 461  LYS A NZ  1 
ATOM   3363 N N   . GLU A 1 503  ? 141.709 83.292  77.879  1.00 115.07 ? 462  GLU A N   1 
ATOM   3364 C CA  . GLU A 1 503  ? 140.351 82.941  77.467  1.00 115.07 ? 462  GLU A CA  1 
ATOM   3365 C C   . GLU A 1 503  ? 139.986 83.590  76.137  1.00 115.07 ? 462  GLU A C   1 
ATOM   3366 O O   . GLU A 1 503  ? 139.197 83.030  75.358  1.00 115.07 ? 462  GLU A O   1 
ATOM   3367 C CB  . GLU A 1 503  ? 139.358 83.349  78.554  1.00 115.07 ? 462  GLU A CB  1 
ATOM   3368 C CG  . GLU A 1 503  ? 137.957 82.793  78.373  1.00 115.07 ? 462  GLU A CG  1 
ATOM   3369 C CD  . GLU A 1 503  ? 137.732 81.522  79.168  1.00 115.07 ? 462  GLU A CD  1 
ATOM   3370 O OE1 . GLU A 1 503  ? 138.730 80.864  79.535  1.00 115.07 ? 462  GLU A OE1 1 
ATOM   3371 O OE2 . GLU A 1 503  ? 136.560 81.181  79.430  1.00 115.07 ? 462  GLU A OE2 1 
ATOM   3372 N N   . ASN A 1 504  ? 140.544 84.773  75.863  1.00 112.06 ? 463  ASN A N   1 
ATOM   3373 C CA  . ASN A 1 504  ? 140.382 85.417  74.569  1.00 112.06 ? 463  ASN A CA  1 
ATOM   3374 C C   . ASN A 1 504  ? 141.054 84.642  73.448  1.00 112.06 ? 463  ASN A C   1 
ATOM   3375 O O   . ASN A 1 504  ? 140.813 84.946  72.275  1.00 112.06 ? 463  ASN A O   1 
ATOM   3376 C CB  . ASN A 1 504  ? 140.930 86.841  74.611  1.00 112.06 ? 463  ASN A CB  1 
ATOM   3377 C CG  . ASN A 1 504  ? 139.839 87.876  74.755  1.00 112.06 ? 463  ASN A CG  1 
ATOM   3378 O OD1 . ASN A 1 504  ? 138.755 87.728  74.197  1.00 112.06 ? 463  ASN A OD1 1 
ATOM   3379 N ND2 . ASN A 1 504  ? 140.121 88.935  75.500  1.00 112.06 ? 463  ASN A ND2 1 
ATOM   3380 N N   . ILE A 1 505  ? 141.904 83.674  73.776  1.00 118.73 ? 464  ILE A N   1 
ATOM   3381 C CA  . ILE A 1 505  ? 142.425 82.743  72.784  1.00 118.73 ? 464  ILE A CA  1 
ATOM   3382 C C   . ILE A 1 505  ? 141.538 81.503  72.772  1.00 118.73 ? 464  ILE A C   1 
ATOM   3383 O O   . ILE A 1 505  ? 141.258 80.941  71.710  1.00 118.73 ? 464  ILE A O   1 
ATOM   3384 C CB  . ILE A 1 505  ? 143.897 82.387  73.066  1.00 118.73 ? 464  ILE A CB  1 
ATOM   3385 C CG1 . ILE A 1 505  ? 144.747 83.653  73.155  1.00 118.73 ? 464  ILE A CG1 1 
ATOM   3386 C CG2 . ILE A 1 505  ? 144.451 81.495  71.983  1.00 118.73 ? 464  ILE A CG2 1 
ATOM   3387 C CD1 . ILE A 1 505  ? 145.060 84.275  71.815  1.00 118.73 ? 464  ILE A CD1 1 
ATOM   3388 N N   . LEU A 1 506  ? 141.073 81.085  73.955  1.00 120.75 ? 465  LEU A N   1 
ATOM   3389 C CA  . LEU A 1 506  ? 140.210 79.903  74.036  1.00 120.75 ? 465  LEU A CA  1 
ATOM   3390 C C   . LEU A 1 506  ? 138.974 80.022  73.157  1.00 120.75 ? 465  LEU A C   1 
ATOM   3391 O O   . LEU A 1 506  ? 138.643 79.079  72.430  1.00 120.75 ? 465  LEU A O   1 
ATOM   3392 C CB  . LEU A 1 506  ? 139.764 79.611  75.470  1.00 120.75 ? 465  LEU A CB  1 
ATOM   3393 C CG  . LEU A 1 506  ? 140.608 78.819  76.464  1.00 120.75 ? 465  LEU A CG  1 
ATOM   3394 C CD1 . LEU A 1 506  ? 140.762 77.400  75.944  1.00 120.75 ? 465  LEU A CD1 1 
ATOM   3395 C CD2 . LEU A 1 506  ? 141.942 79.422  76.673  1.00 120.75 ? 465  LEU A CD2 1 
ATOM   3396 N N   . LEU A 1 507  ? 138.270 81.156  73.213  1.00 114.23 ? 466  LEU A N   1 
ATOM   3397 C CA  . LEU A 1 507  ? 136.923 81.130  72.635  1.00 114.23 ? 466  LEU A CA  1 
ATOM   3398 C C   . LEU A 1 507  ? 136.927 80.836  71.139  1.00 114.23 ? 466  LEU A C   1 
ATOM   3399 O O   . LEU A 1 507  ? 135.854 80.618  70.569  1.00 114.23 ? 466  LEU A O   1 
ATOM   3400 C CB  . LEU A 1 507  ? 136.154 82.432  72.868  1.00 114.23 ? 466  LEU A CB  1 
ATOM   3401 C CG  . LEU A 1 507  ? 136.502 83.702  72.102  1.00 114.23 ? 466  LEU A CG  1 
ATOM   3402 C CD1 . LEU A 1 507  ? 135.367 84.692  72.246  1.00 114.23 ? 466  LEU A CD1 1 
ATOM   3403 C CD2 . LEU A 1 507  ? 137.761 84.301  72.619  1.00 114.23 ? 466  LEU A CD2 1 
ATOM   3404 N N   . GLY A 1 508  ? 138.095 80.829  70.494  1.00 118.44 ? 467  GLY A N   1 
ATOM   3405 C CA  . GLY A 1 508  ? 138.172 80.310  69.138  1.00 118.44 ? 467  GLY A CA  1 
ATOM   3406 C C   . GLY A 1 508  ? 137.843 78.831  69.068  1.00 118.44 ? 467  GLY A C   1 
ATOM   3407 O O   . GLY A 1 508  ? 137.126 78.386  68.168  1.00 118.44 ? 467  GLY A O   1 
ATOM   3408 N N   . ARG A 1 509  ? 138.359 78.050  70.016  1.00 128.20 ? 468  ARG A N   1 
ATOM   3409 C CA  . ARG A 1 509  ? 138.039 76.626  70.119  1.00 128.20 ? 468  ARG A CA  1 
ATOM   3410 C C   . ARG A 1 509  ? 138.133 76.231  71.584  1.00 128.20 ? 468  ARG A C   1 
ATOM   3411 O O   . ARG A 1 509  ? 139.236 76.014  72.111  1.00 128.20 ? 468  ARG A O   1 
ATOM   3412 C CB  . ARG A 1 509  ? 138.962 75.761  69.265  1.00 128.20 ? 468  ARG A CB  1 
ATOM   3413 C CG  . ARG A 1 509  ? 138.667 74.274  69.381  1.00 128.20 ? 468  ARG A CG  1 
ATOM   3414 C CD  . ARG A 1 509  ? 139.591 73.434  68.518  1.00 128.20 ? 468  ARG A CD  1 
ATOM   3415 N NE  . ARG A 1 509  ? 140.997 73.656  68.829  1.00 128.20 ? 468  ARG A NE  1 
ATOM   3416 C CZ  . ARG A 1 509  ? 141.987 73.502  67.960  1.00 128.20 ? 468  ARG A CZ  1 
ATOM   3417 N NH1 . ARG A 1 509  ? 141.760 73.132  66.712  1.00 128.20 ? 468  ARG A NH1 1 
ATOM   3418 N NH2 . ARG A 1 509  ? 143.238 73.724  68.355  1.00 128.20 ? 468  ARG A NH2 1 
ATOM   3419 N N   . PRO A 1 510  ? 137.000 76.135  72.283  1.00 131.54 ? 469  PRO A N   1 
ATOM   3420 C CA  . PRO A 1 510  ? 137.050 75.761  73.706  1.00 131.54 ? 469  PRO A CA  1 
ATOM   3421 C C   . PRO A 1 510  ? 137.626 74.377  73.951  1.00 131.54 ? 469  PRO A C   1 
ATOM   3422 O O   . PRO A 1 510  ? 138.184 74.131  75.028  1.00 131.54 ? 469  PRO A O   1 
ATOM   3423 C CB  . PRO A 1 510  ? 135.581 75.848  74.140  1.00 131.54 ? 469  PRO A CB  1 
ATOM   3424 C CG  . PRO A 1 510  ? 134.801 75.680  72.878  1.00 131.54 ? 469  PRO A CG  1 
ATOM   3425 C CD  . PRO A 1 510  ? 135.622 76.321  71.802  1.00 131.54 ? 469  PRO A CD  1 
ATOM   3426 N N   . ASP A 1 511  ? 137.510 73.464  72.985  1.00 136.75 ? 470  ASP A N   1 
ATOM   3427 C CA  . ASP A 1 511  ? 137.988 72.100  73.172  1.00 136.75 ? 470  ASP A CA  1 
ATOM   3428 C C   . ASP A 1 511  ? 139.506 72.001  73.229  1.00 136.75 ? 470  ASP A C   1 
ATOM   3429 O O   . ASP A 1 511  ? 140.025 70.945  73.603  1.00 136.75 ? 470  ASP A O   1 
ATOM   3430 C CB  . ASP A 1 511  ? 137.459 71.203  72.052  1.00 136.75 ? 470  ASP A CB  1 
ATOM   3431 C CG  . ASP A 1 511  ? 135.960 71.319  71.872  1.00 136.75 ? 470  ASP A CG  1 
ATOM   3432 O OD1 . ASP A 1 511  ? 135.276 71.738  72.830  1.00 136.75 ? 470  ASP A OD1 1 
ATOM   3433 O OD2 . ASP A 1 511  ? 135.465 70.990  70.774  1.00 136.75 ? 470  ASP A OD2 1 
ATOM   3434 N N   . ALA A 1 512  ? 140.225 73.061  72.872  1.00 144.13 ? 471  ALA A N   1 
ATOM   3435 C CA  . ALA A 1 512  ? 141.677 73.015  72.887  1.00 144.13 ? 471  ALA A CA  1 
ATOM   3436 C C   . ALA A 1 512  ? 142.201 72.986  74.320  1.00 144.13 ? 471  ALA A C   1 
ATOM   3437 O O   . ALA A 1 512  ? 141.518 73.378  75.270  1.00 144.13 ? 471  ALA A O   1 
ATOM   3438 C CB  . ALA A 1 512  ? 142.259 74.215  72.140  1.00 144.13 ? 471  ALA A CB  1 
ATOM   3439 N N   . ASP A 1 513  ? 143.431 72.509  74.465  1.00 155.60 ? 472  ASP A N   1 
ATOM   3440 C CA  . ASP A 1 513  ? 144.117 72.460  75.747  1.00 155.60 ? 472  ASP A CA  1 
ATOM   3441 C C   . ASP A 1 513  ? 145.189 73.543  75.796  1.00 155.60 ? 472  ASP A C   1 
ATOM   3442 O O   . ASP A 1 513  ? 145.387 74.301  74.844  1.00 155.60 ? 472  ASP A O   1 
ATOM   3443 C CB  . ASP A 1 513  ? 144.723 71.075  75.988  1.00 155.60 ? 472  ASP A CB  1 
ATOM   3444 C CG  . ASP A 1 513  ? 145.952 70.820  75.139  1.00 155.60 ? 472  ASP A CG  1 
ATOM   3445 O OD1 . ASP A 1 513  ? 145.972 71.257  73.970  1.00 155.60 ? 472  ASP A OD1 1 
ATOM   3446 O OD2 . ASP A 1 513  ? 146.903 70.186  75.643  1.00 155.60 ? 472  ASP A OD2 1 
ATOM   3447 N N   . GLN A 1 514  ? 145.891 73.600  76.929  1.00 156.81 ? 473  GLN A N   1 
ATOM   3448 C CA  . GLN A 1 514  ? 146.923 74.614  77.118  1.00 156.81 ? 473  GLN A CA  1 
ATOM   3449 C C   . GLN A 1 514  ? 148.050 74.429  76.107  1.00 156.81 ? 473  GLN A C   1 
ATOM   3450 O O   . GLN A 1 514  ? 148.524 75.400  75.505  1.00 156.81 ? 473  GLN A O   1 
ATOM   3451 C CB  . GLN A 1 514  ? 147.441 74.535  78.558  1.00 156.81 ? 473  GLN A CB  1 
ATOM   3452 C CG  . GLN A 1 514  ? 148.771 75.216  78.909  1.00 156.81 ? 473  GLN A CG  1 
ATOM   3453 C CD  . GLN A 1 514  ? 148.930 76.611  78.329  1.00 156.81 ? 473  GLN A CD  1 
ATOM   3454 O OE1 . GLN A 1 514  ? 149.601 76.813  77.320  1.00 156.81 ? 473  GLN A OE1 1 
ATOM   3455 N NE2 . GLN A 1 514  ? 148.288 77.585  78.964  1.00 156.81 ? 473  GLN A NE2 1 
ATOM   3456 N N   . VAL A 1 515  ? 148.454 73.178  75.871  1.00 160.80 ? 474  VAL A N   1 
ATOM   3457 C CA  . VAL A 1 515  ? 149.590 72.902  74.992  1.00 160.80 ? 474  VAL A CA  1 
ATOM   3458 C C   . VAL A 1 515  ? 149.303 73.387  73.574  1.00 160.80 ? 474  VAL A C   1 
ATOM   3459 O O   . VAL A 1 515  ? 150.158 74.003  72.926  1.00 160.80 ? 474  VAL A O   1 
ATOM   3460 C CB  . VAL A 1 515  ? 149.930 71.402  75.014  1.00 160.80 ? 474  VAL A CB  1 
ATOM   3461 C CG1 . VAL A 1 515  ? 151.103 71.108  74.091  1.00 160.80 ? 474  VAL A CG1 1 
ATOM   3462 C CG2 . VAL A 1 515  ? 150.233 70.950  76.435  1.00 160.80 ? 474  VAL A CG2 1 
ATOM   3463 N N   . GLU A 1 516  ? 148.099 73.108  73.069  1.00 156.35 ? 475  GLU A N   1 
ATOM   3464 C CA  . GLU A 1 516  ? 147.745 73.556  71.725  1.00 156.35 ? 475  GLU A CA  1 
ATOM   3465 C C   . GLU A 1 516  ? 147.753 75.075  71.635  1.00 156.35 ? 475  GLU A C   1 
ATOM   3466 O O   . GLU A 1 516  ? 148.242 75.647  70.654  1.00 156.35 ? 475  GLU A O   1 
ATOM   3467 C CB  . GLU A 1 516  ? 146.378 73.001  71.328  1.00 156.35 ? 475  GLU A CB  1 
ATOM   3468 C CG  . GLU A 1 516  ? 146.422 71.592  70.764  1.00 156.35 ? 475  GLU A CG  1 
ATOM   3469 C CD  . GLU A 1 516  ? 145.071 71.125  70.261  1.00 156.35 ? 475  GLU A CD  1 
ATOM   3470 O OE1 . GLU A 1 516  ? 144.061 71.793  70.565  1.00 156.35 ? 475  GLU A OE1 1 
ATOM   3471 O OE2 . GLU A 1 516  ? 145.021 70.091  69.563  1.00 156.35 ? 475  GLU A OE2 1 
ATOM   3472 N N   . ILE A 1 517  ? 147.230 75.746  72.663  1.00 157.31 ? 476  ILE A N   1 
ATOM   3473 C CA  . ILE A 1 517  ? 147.186 77.205  72.667  1.00 157.31 ? 476  ILE A CA  1 
ATOM   3474 C C   . ILE A 1 517  ? 148.594 77.779  72.625  1.00 157.31 ? 476  ILE A C   1 
ATOM   3475 O O   . ILE A 1 517  ? 148.897 78.674  71.824  1.00 157.31 ? 476  ILE A O   1 
ATOM   3476 C CB  . ILE A 1 517  ? 146.420 77.701  73.903  1.00 157.31 ? 476  ILE A CB  1 
ATOM   3477 C CG1 . ILE A 1 517  ? 144.977 77.219  73.846  1.00 157.31 ? 476  ILE A CG1 1 
ATOM   3478 C CG2 . ILE A 1 517  ? 146.486 79.214  73.997  1.00 157.31 ? 476  ILE A CG2 1 
ATOM   3479 C CD1 . ILE A 1 517  ? 144.260 77.371  75.142  1.00 157.31 ? 476  ILE A CD1 1 
ATOM   3480 N N   . GLU A 1 518  ? 149.476 77.273  73.488  1.00 164.19 ? 477  GLU A N   1 
ATOM   3481 C CA  . GLU A 1 518  ? 150.825 77.821  73.541  1.00 164.19 ? 477  GLU A CA  1 
ATOM   3482 C C   . GLU A 1 518  ? 151.593 77.525  72.259  1.00 164.19 ? 477  GLU A C   1 
ATOM   3483 O O   . GLU A 1 518  ? 152.317 78.391  71.758  1.00 164.19 ? 477  GLU A O   1 
ATOM   3484 C CB  . GLU A 1 518  ? 151.576 77.297  74.768  1.00 164.19 ? 477  GLU A CB  1 
ATOM   3485 C CG  . GLU A 1 518  ? 151.688 75.793  74.873  1.00 164.19 ? 477  GLU A CG  1 
ATOM   3486 C CD  . GLU A 1 518  ? 152.925 75.248  74.189  1.00 164.19 ? 477  GLU A CD  1 
ATOM   3487 O OE1 . GLU A 1 518  ? 153.911 76.003  74.056  1.00 164.19 ? 477  GLU A OE1 1 
ATOM   3488 O OE2 . GLU A 1 518  ? 152.908 74.068  73.780  1.00 164.19 ? 477  GLU A OE2 1 
ATOM   3489 N N   . GLU A 1 519  ? 151.443 76.322  71.696  1.00 165.53 ? 478  GLU A N   1 
ATOM   3490 C CA  . GLU A 1 519  ? 152.167 76.030  70.464  1.00 165.53 ? 478  GLU A CA  1 
ATOM   3491 C C   . GLU A 1 519  ? 151.650 76.887  69.314  1.00 165.53 ? 478  GLU A C   1 
ATOM   3492 O O   . GLU A 1 519  ? 152.436 77.357  68.488  1.00 165.53 ? 478  GLU A O   1 
ATOM   3493 C CB  . GLU A 1 519  ? 152.094 74.537  70.123  1.00 165.53 ? 478  GLU A CB  1 
ATOM   3494 C CG  . GLU A 1 519  ? 150.716 73.982  69.813  1.00 165.53 ? 478  GLU A CG  1 
ATOM   3495 C CD  . GLU A 1 519  ? 150.340 74.117  68.351  1.00 165.53 ? 478  GLU A CD  1 
ATOM   3496 O OE1 . GLU A 1 519  ? 151.253 74.282  67.514  1.00 165.53 ? 478  GLU A OE1 1 
ATOM   3497 O OE2 . GLU A 1 519  ? 149.132 74.065  68.037  1.00 165.53 ? 478  GLU A OE2 1 
ATOM   3498 N N   . ALA A 1 520  ? 150.336 77.124  69.258  1.00 164.84 ? 479  ALA A N   1 
ATOM   3499 C CA  . ALA A 1 520  ? 149.793 78.006  68.231  1.00 164.84 ? 479  ALA A CA  1 
ATOM   3500 C C   . ALA A 1 520  ? 150.320 79.424  68.397  1.00 164.84 ? 479  ALA A C   1 
ATOM   3501 O O   . ALA A 1 520  ? 150.655 80.095  67.414  1.00 164.84 ? 479  ALA A O   1 
ATOM   3502 C CB  . ALA A 1 520  ? 148.266 77.989  68.276  1.00 164.84 ? 479  ALA A CB  1 
ATOM   3503 N N   . ALA A 1 521  ? 150.405 79.897  69.640  1.00 165.66 ? 480  ALA A N   1 
ATOM   3504 C CA  . ALA A 1 521  ? 150.905 81.245  69.881  1.00 165.66 ? 480  ALA A CA  1 
ATOM   3505 C C   . ALA A 1 521  ? 152.408 81.362  69.664  1.00 165.66 ? 480  ALA A C   1 
ATOM   3506 O O   . ALA A 1 521  ? 152.904 82.475  69.465  1.00 165.66 ? 480  ALA A O   1 
ATOM   3507 C CB  . ALA A 1 521  ? 150.550 81.690  71.299  1.00 165.66 ? 480  ALA A CB  1 
ATOM   3508 N N   . ARG A 1 522  ? 153.147 80.254  69.712  1.00 166.07 ? 481  ARG A N   1 
ATOM   3509 C CA  . ARG A 1 522  ? 154.599 80.315  69.597  1.00 166.07 ? 481  ARG A CA  1 
ATOM   3510 C C   . ARG A 1 522  ? 155.126 80.022  68.199  1.00 166.07 ? 481  ARG A C   1 
ATOM   3511 O O   . ARG A 1 522  ? 156.000 80.752  67.722  1.00 166.07 ? 481  ARG A O   1 
ATOM   3512 C CB  . ARG A 1 522  ? 155.257 79.347  70.589  1.00 166.07 ? 481  ARG A CB  1 
ATOM   3513 C CG  . ARG A 1 522  ? 155.086 79.737  72.053  1.00 166.07 ? 481  ARG A CG  1 
ATOM   3514 C CD  . ARG A 1 522  ? 156.055 80.830  72.471  1.00 166.07 ? 481  ARG A CD  1 
ATOM   3515 N NE  . ARG A 1 522  ? 155.577 82.160  72.110  1.00 166.07 ? 481  ARG A NE  1 
ATOM   3516 C CZ  . ARG A 1 522  ? 154.712 82.866  72.824  1.00 166.07 ? 481  ARG A CZ  1 
ATOM   3517 N NH1 . ARG A 1 522  ? 154.205 82.400  73.954  1.00 166.07 ? 481  ARG A NH1 1 
ATOM   3518 N NH2 . ARG A 1 522  ? 154.342 84.069  72.393  1.00 166.07 ? 481  ARG A NH2 1 
ATOM   3519 N N   . VAL A 1 523  ? 154.637 78.981  67.527  1.00 168.67 ? 482  VAL A N   1 
ATOM   3520 C CA  . VAL A 1 523  ? 155.183 78.648  66.215  1.00 168.67 ? 482  VAL A CA  1 
ATOM   3521 C C   . VAL A 1 523  ? 154.686 79.617  65.145  1.00 168.67 ? 482  VAL A C   1 
ATOM   3522 O O   . VAL A 1 523  ? 155.383 79.854  64.154  1.00 168.67 ? 482  VAL A O   1 
ATOM   3523 C CB  . VAL A 1 523  ? 154.857 77.192  65.830  1.00 168.67 ? 482  VAL A CB  1 
ATOM   3524 C CG1 . VAL A 1 523  ? 153.363 77.001  65.611  1.00 168.67 ? 482  VAL A CG1 1 
ATOM   3525 C CG2 . VAL A 1 523  ? 155.648 76.766  64.600  1.00 168.67 ? 482  VAL A CG2 1 
ATOM   3526 N N   . ALA A 1 524  ? 153.502 80.196  65.332  1.00 164.24 ? 483  ALA A N   1 
ATOM   3527 C CA  . ALA A 1 524  ? 152.915 81.096  64.354  1.00 164.24 ? 483  ALA A CA  1 
ATOM   3528 C C   . ALA A 1 524  ? 152.806 82.530  64.852  1.00 164.24 ? 483  ALA A C   1 
ATOM   3529 O O   . ALA A 1 524  ? 152.199 83.362  64.172  1.00 164.24 ? 483  ALA A O   1 
ATOM   3530 C CB  . ALA A 1 524  ? 151.538 80.581  63.932  1.00 164.24 ? 483  ALA A CB  1 
ATOM   3531 N N   . ASN A 1 525  ? 153.369 82.835  66.018  1.00 161.11 ? 484  ASN A N   1 
ATOM   3532 C CA  . ASN A 1 525  ? 153.497 84.207  66.482  1.00 161.11 ? 484  ASN A CA  1 
ATOM   3533 C C   . ASN A 1 525  ? 154.780 84.316  67.291  1.00 161.11 ? 484  ASN A C   1 
ATOM   3534 O O   . ASN A 1 525  ? 155.157 83.386  68.008  1.00 161.11 ? 484  ASN A O   1 
ATOM   3535 C CB  . ASN A 1 525  ? 152.301 84.648  67.334  1.00 161.11 ? 484  ASN A CB  1 
ATOM   3536 C CG  . ASN A 1 525  ? 151.038 84.824  66.522  1.00 161.11 ? 484  ASN A CG  1 
ATOM   3537 O OD1 . ASN A 1 525  ? 150.854 85.835  65.849  1.00 161.11 ? 484  ASN A OD1 1 
ATOM   3538 N ND2 . ASN A 1 525  ? 150.157 83.835  66.583  1.00 161.11 ? 484  ASN A ND2 1 
ATOM   3539 N N   . ALA A 1 526  ? 155.443 85.460  67.173  1.00 166.47 ? 485  ALA A N   1 
ATOM   3540 C CA  . ALA A 1 526  ? 156.683 85.672  67.899  1.00 166.47 ? 485  ALA A CA  1 
ATOM   3541 C C   . ALA A 1 526  ? 156.403 85.911  69.379  1.00 166.47 ? 485  ALA A C   1 
ATOM   3542 O O   . ALA A 1 526  ? 155.286 86.248  69.781  1.00 166.47 ? 485  ALA A O   1 
ATOM   3543 C CB  . ALA A 1 526  ? 157.458 86.852  67.314  1.00 166.47 ? 485  ALA A CB  1 
ATOM   3544 N N   . HIS A 1 527  ? 157.437 85.716  70.194  1.00 167.84 ? 486  HIS A N   1 
ATOM   3545 C CA  . HIS A 1 527  ? 157.334 86.013  71.616  1.00 167.84 ? 486  HIS A CA  1 
ATOM   3546 C C   . HIS A 1 527  ? 157.004 87.486  71.804  1.00 167.84 ? 486  HIS A C   1 
ATOM   3547 O O   . HIS A 1 527  ? 157.604 88.356  71.166  1.00 167.84 ? 486  HIS A O   1 
ATOM   3548 C CB  . HIS A 1 527  ? 158.639 85.659  72.327  1.00 167.84 ? 486  HIS A CB  1 
ATOM   3549 C CG  . HIS A 1 527  ? 158.987 84.205  72.260  1.00 167.84 ? 486  HIS A CG  1 
ATOM   3550 N ND1 . HIS A 1 527  ? 159.893 83.699  71.354  1.00 167.84 ? 486  HIS A ND1 1 
ATOM   3551 C CD2 . HIS A 1 527  ? 158.550 83.149  72.986  1.00 167.84 ? 486  HIS A CD2 1 
ATOM   3552 C CE1 . HIS A 1 527  ? 160.000 82.393  71.523  1.00 167.84 ? 486  HIS A CE1 1 
ATOM   3553 N NE2 . HIS A 1 527  ? 159.196 82.035  72.508  1.00 167.84 ? 486  HIS A NE2 1 
ATOM   3554 N N   . SER A 1 528  ? 156.050 87.766  72.681  1.00 164.66 ? 487  SER A N   1 
ATOM   3555 C CA  . SER A 1 528  ? 155.465 89.096  72.737  1.00 164.66 ? 487  SER A CA  1 
ATOM   3556 C C   . SER A 1 528  ? 155.080 89.400  74.179  1.00 164.66 ? 487  SER A C   1 
ATOM   3557 O O   . SER A 1 528  ? 155.542 88.737  75.114  1.00 164.66 ? 487  SER A O   1 
ATOM   3558 C CB  . SER A 1 528  ? 154.273 89.196  71.771  1.00 164.66 ? 487  SER A CB  1 
ATOM   3559 O OG  . SER A 1 528  ? 153.584 90.419  71.951  1.00 164.66 ? 487  SER A OG  1 
ATOM   3560 N N   . PHE A 1 529  ? 154.223 90.408  74.354  1.00 162.79 ? 488  PHE A N   1 
ATOM   3561 C CA  . PHE A 1 529  ? 153.889 90.913  75.679  1.00 162.79 ? 488  PHE A CA  1 
ATOM   3562 C C   . PHE A 1 529  ? 153.193 89.875  76.548  1.00 162.79 ? 488  PHE A C   1 
ATOM   3563 O O   . PHE A 1 529  ? 153.113 90.064  77.766  1.00 162.79 ? 488  PHE A O   1 
ATOM   3564 C CB  . PHE A 1 529  ? 153.010 92.158  75.542  1.00 162.79 ? 488  PHE A CB  1 
ATOM   3565 C CG  . PHE A 1 529  ? 152.926 92.986  76.792  1.00 162.79 ? 488  PHE A CG  1 
ATOM   3566 C CD1 . PHE A 1 529  ? 154.076 93.387  77.453  1.00 162.79 ? 488  PHE A CD1 1 
ATOM   3567 C CD2 . PHE A 1 529  ? 151.697 93.378  77.298  1.00 162.79 ? 488  PHE A CD2 1 
ATOM   3568 C CE1 . PHE A 1 529  ? 154.001 94.154  78.600  1.00 162.79 ? 488  PHE A CE1 1 
ATOM   3569 C CE2 . PHE A 1 529  ? 151.615 94.147  78.443  1.00 162.79 ? 488  PHE A CE2 1 
ATOM   3570 C CZ  . PHE A 1 529  ? 152.770 94.535  79.096  1.00 162.79 ? 488  PHE A CZ  1 
ATOM   3571 N N   . ILE A 1 530  ? 152.688 88.789  75.959  1.00 163.33 ? 489  ILE A N   1 
ATOM   3572 C CA  . ILE A 1 530  ? 151.954 87.804  76.747  1.00 163.33 ? 489  ILE A CA  1 
ATOM   3573 C C   . ILE A 1 530  ? 152.865 87.111  77.754  1.00 163.33 ? 489  ILE A C   1 
ATOM   3574 O O   . ILE A 1 530  ? 152.432 86.782  78.864  1.00 163.33 ? 489  ILE A O   1 
ATOM   3575 C CB  . ILE A 1 530  ? 151.250 86.789  75.825  1.00 163.33 ? 489  ILE A CB  1 
ATOM   3576 C CG1 . ILE A 1 530  ? 152.268 85.958  75.041  1.00 163.33 ? 489  ILE A CG1 1 
ATOM   3577 C CG2 . ILE A 1 530  ? 150.300 87.506  74.876  1.00 163.33 ? 489  ILE A CG2 1 
ATOM   3578 C CD1 . ILE A 1 530  ? 151.757 84.591  74.646  1.00 163.33 ? 489  ILE A CD1 1 
ATOM   3579 N N   . ILE A 1 531  ? 154.129 86.877  77.399  1.00 165.20 ? 490  ILE A N   1 
ATOM   3580 C CA  . ILE A 1 531  ? 155.049 86.175  78.289  1.00 165.20 ? 490  ILE A CA  1 
ATOM   3581 C C   . ILE A 1 531  ? 155.898 87.182  79.056  1.00 165.20 ? 490  ILE A C   1 
ATOM   3582 O O   . ILE A 1 531  ? 156.263 86.945  80.213  1.00 165.20 ? 490  ILE A O   1 
ATOM   3583 C CB  . ILE A 1 531  ? 155.922 85.171  77.514  1.00 165.20 ? 490  ILE A CB  1 
ATOM   3584 C CG1 . ILE A 1 531  ? 156.778 85.884  76.467  1.00 165.20 ? 490  ILE A CG1 1 
ATOM   3585 C CG2 . ILE A 1 531  ? 155.056 84.109  76.861  1.00 165.20 ? 490  ILE A CG2 1 
ATOM   3586 C CD1 . ILE A 1 531  ? 157.821 84.997  75.834  1.00 165.20 ? 490  ILE A CD1 1 
ATOM   3587 N N   . LYS A 1 532  ? 156.217 88.312  78.423  1.00 163.57 ? 491  LYS A N   1 
ATOM   3588 C CA  . LYS A 1 532  ? 156.920 89.404  79.096  1.00 163.57 ? 491  LYS A CA  1 
ATOM   3589 C C   . LYS A 1 532  ? 155.895 90.222  79.880  1.00 163.57 ? 491  LYS A C   1 
ATOM   3590 O O   . LYS A 1 532  ? 155.604 91.383  79.588  1.00 163.57 ? 491  LYS A O   1 
ATOM   3591 C CB  . LYS A 1 532  ? 157.676 90.262  78.090  1.00 163.57 ? 491  LYS A CB  1 
ATOM   3592 C CG  . LYS A 1 532  ? 159.106 89.816  77.832  1.00 163.57 ? 491  LYS A CG  1 
ATOM   3593 C CD  . LYS A 1 532  ? 159.145 88.563  76.974  1.00 163.57 ? 491  LYS A CD  1 
ATOM   3594 C CE  . LYS A 1 532  ? 160.453 88.448  76.213  1.00 163.57 ? 491  LYS A CE  1 
ATOM   3595 N NZ  . LYS A 1 532  ? 160.375 87.419  75.141  1.00 163.57 ? 491  LYS A NZ  1 
ATOM   3596 N N   . LEU A 1 533  ? 155.340 89.578  80.909  1.00 156.30 ? 492  LEU A N   1 
ATOM   3597 C CA  . LEU A 1 533  ? 154.185 90.107  81.588  1.00 156.30 ? 492  LEU A CA  1 
ATOM   3598 C C   . LEU A 1 533  ? 154.132 89.566  83.009  1.00 156.30 ? 492  LEU A C   1 
ATOM   3599 O O   . LEU A 1 533  ? 154.393 88.370  83.211  1.00 156.30 ? 492  LEU A O   1 
ATOM   3600 C CB  . LEU A 1 533  ? 152.918 89.725  80.827  1.00 156.30 ? 492  LEU A CB  1 
ATOM   3601 C CG  . LEU A 1 533  ? 151.560 90.305  81.201  1.00 156.30 ? 492  LEU A CG  1 
ATOM   3602 C CD1 . LEU A 1 533  ? 151.578 91.806  81.056  1.00 156.30 ? 492  LEU A CD1 1 
ATOM   3603 C CD2 . LEU A 1 533  ? 150.520 89.713  80.276  1.00 156.30 ? 492  LEU A CD2 1 
ATOM   3604 N N   . PRO A 1 534  ? 153.819 90.404  84.002  1.00 154.25 ? 493  PRO A N   1 
ATOM   3605 C CA  . PRO A 1 534  ? 153.746 89.902  85.383  1.00 154.25 ? 493  PRO A CA  1 
ATOM   3606 C C   . PRO A 1 534  ? 152.730 88.793  85.572  1.00 154.25 ? 493  PRO A C   1 
ATOM   3607 O O   . PRO A 1 534  ? 152.963 87.882  86.376  1.00 154.25 ? 493  PRO A O   1 
ATOM   3608 C CB  . PRO A 1 534  ? 153.371 91.152  86.191  1.00 154.25 ? 493  PRO A CB  1 
ATOM   3609 C CG  . PRO A 1 534  ? 153.775 92.303  85.335  1.00 154.25 ? 493  PRO A CG  1 
ATOM   3610 C CD  . PRO A 1 534  ? 153.585 91.854  83.924  1.00 154.25 ? 493  PRO A CD  1 
ATOM   3611 N N   . ASP A 1 535  ? 151.606 88.840  84.857  1.00 146.51 ? 494  ASP A N   1 
ATOM   3612 C CA  . ASP A 1 535  ? 150.545 87.852  85.010  1.00 146.51 ? 494  ASP A CA  1 
ATOM   3613 C C   . ASP A 1 535  ? 150.590 86.794  83.912  1.00 146.51 ? 494  ASP A C   1 
ATOM   3614 O O   . ASP A 1 535  ? 150.718 85.600  84.199  1.00 146.51 ? 494  ASP A O   1 
ATOM   3615 C CB  . ASP A 1 535  ? 149.186 88.560  85.022  1.00 146.51 ? 494  ASP A CB  1 
ATOM   3616 C CG  . ASP A 1 535  ? 149.127 89.684  86.035  1.00 146.51 ? 494  ASP A CG  1 
ATOM   3617 O OD1 . ASP A 1 535  ? 149.784 89.566  87.090  1.00 146.51 ? 494  ASP A OD1 1 
ATOM   3618 O OD2 . ASP A 1 535  ? 148.433 90.686  85.774  1.00 146.51 ? 494  ASP A OD2 1 
ATOM   3619 N N   . GLY A 1 536  ? 150.498 87.214  82.653  1.00 145.60 ? 495  GLY A N   1 
ATOM   3620 C CA  . GLY A 1 536  ? 150.538 86.286  81.541  1.00 145.60 ? 495  GLY A CA  1 
ATOM   3621 C C   . GLY A 1 536  ? 149.183 85.729  81.156  1.00 145.60 ? 495  GLY A C   1 
ATOM   3622 O O   . GLY A 1 536  ? 148.357 86.430  80.565  1.00 145.60 ? 495  GLY A O   1 
ATOM   3623 N N   . PHE A 1 537  ? 148.949 84.458  81.490  1.00 139.68 ? 496  PHE A N   1 
ATOM   3624 C CA  . PHE A 1 537  ? 147.702 83.804  81.109  1.00 139.68 ? 496  PHE A CA  1 
ATOM   3625 C C   . PHE A 1 537  ? 146.508 84.348  81.882  1.00 139.68 ? 496  PHE A C   1 
ATOM   3626 O O   . PHE A 1 537  ? 145.389 84.364  81.358  1.00 139.68 ? 496  PHE A O   1 
ATOM   3627 C CB  . PHE A 1 537  ? 147.826 82.295  81.310  1.00 139.68 ? 496  PHE A CB  1 
ATOM   3628 C CG  . PHE A 1 537  ? 148.639 81.611  80.248  1.00 139.68 ? 496  PHE A CG  1 
ATOM   3629 C CD1 . PHE A 1 537  ? 148.555 82.017  78.926  1.00 139.68 ? 496  PHE A CD1 1 
ATOM   3630 C CD2 . PHE A 1 537  ? 149.495 80.571  80.572  1.00 139.68 ? 496  PHE A CD2 1 
ATOM   3631 C CE1 . PHE A 1 537  ? 149.302 81.392  77.945  1.00 139.68 ? 496  PHE A CE1 1 
ATOM   3632 C CE2 . PHE A 1 537  ? 150.247 79.945  79.595  1.00 139.68 ? 496  PHE A CE2 1 
ATOM   3633 C CZ  . PHE A 1 537  ? 150.147 80.355  78.280  1.00 139.68 ? 496  PHE A CZ  1 
ATOM   3634 N N   . ASP A 1 538  ? 146.714 84.810  83.113  1.00 140.92 ? 497  ASP A N   1 
ATOM   3635 C CA  . ASP A 1 538  ? 145.625 85.327  83.940  1.00 140.92 ? 497  ASP A CA  1 
ATOM   3636 C C   . ASP A 1 538  ? 145.542 86.843  83.867  1.00 140.92 ? 497  ASP A C   1 
ATOM   3637 O O   . ASP A 1 538  ? 145.225 87.510  84.855  1.00 140.92 ? 497  ASP A O   1 
ATOM   3638 C CB  . ASP A 1 538  ? 145.785 84.864  85.385  1.00 140.92 ? 497  ASP A CB  1 
ATOM   3639 C CG  . ASP A 1 538  ? 147.140 85.215  85.964  1.00 140.92 ? 497  ASP A CG  1 
ATOM   3640 O OD1 . ASP A 1 538  ? 148.061 85.521  85.179  1.00 140.92 ? 497  ASP A OD1 1 
ATOM   3641 O OD2 . ASP A 1 538  ? 147.284 85.187  87.205  1.00 140.92 ? 497  ASP A OD2 1 
ATOM   3642 N N   . THR A 1 539  ? 145.828 87.410  82.696  1.00 134.18 ? 498  THR A N   1 
ATOM   3643 C CA  . THR A 1 539  ? 145.857 88.860  82.514  1.00 134.18 ? 498  THR A CA  1 
ATOM   3644 C C   . THR A 1 539  ? 144.497 89.322  82.000  1.00 134.18 ? 498  THR A C   1 
ATOM   3645 O O   . THR A 1 539  ? 144.293 89.575  80.812  1.00 134.18 ? 498  THR A O   1 
ATOM   3646 C CB  . THR A 1 539  ? 146.977 89.250  81.561  1.00 134.18 ? 498  THR A CB  1 
ATOM   3647 O OG1 . THR A 1 539  ? 148.180 88.583  81.954  1.00 134.18 ? 498  THR A OG1 1 
ATOM   3648 C CG2 . THR A 1 539  ? 147.208 90.751  81.598  1.00 134.18 ? 498  THR A CG2 1 
ATOM   3649 N N   . GLN A 1 540  ? 143.549 89.434  82.927  1.00 127.77 ? 499  GLN A N   1 
ATOM   3650 C CA  . GLN A 1 540  ? 142.211 89.908  82.592  1.00 127.77 ? 499  GLN A CA  1 
ATOM   3651 C C   . GLN A 1 540  ? 142.288 91.371  82.174  1.00 127.77 ? 499  GLN A C   1 
ATOM   3652 O O   . GLN A 1 540  ? 142.606 92.241  82.990  1.00 127.77 ? 499  GLN A O   1 
ATOM   3653 C CB  . GLN A 1 540  ? 141.274 89.727  83.781  1.00 127.77 ? 499  GLN A CB  1 
ATOM   3654 C CG  . GLN A 1 540  ? 139.908 90.362  83.589  1.00 127.77 ? 499  GLN A CG  1 
ATOM   3655 C CD  . GLN A 1 540  ? 138.788 89.514  84.155  1.00 127.77 ? 499  GLN A CD  1 
ATOM   3656 O OE1 . GLN A 1 540  ? 138.798 88.290  84.032  1.00 127.77 ? 499  GLN A OE1 1 
ATOM   3657 N NE2 . GLN A 1 540  ? 137.811 90.163  84.778  1.00 127.77 ? 499  GLN A NE2 1 
ATOM   3658 N N   . VAL A 1 541  ? 142.002 91.648  80.903  1.00 134.94 ? 500  VAL A N   1 
ATOM   3659 C CA  . VAL A 1 541  ? 142.147 93.009  80.395  1.00 134.94 ? 500  VAL A CA  1 
ATOM   3660 C C   . VAL A 1 541  ? 140.983 93.885  80.848  1.00 134.94 ? 500  VAL A C   1 
ATOM   3661 O O   . VAL A 1 541  ? 141.172 94.846  81.603  1.00 134.94 ? 500  VAL A O   1 
ATOM   3662 C CB  . VAL A 1 541  ? 142.306 93.000  78.861  1.00 134.94 ? 500  VAL A CB  1 
ATOM   3663 C CG1 . VAL A 1 541  ? 143.691 92.513  78.488  1.00 134.94 ? 500  VAL A CG1 1 
ATOM   3664 C CG2 . VAL A 1 541  ? 141.277 92.093  78.207  1.00 134.94 ? 500  VAL A CG2 1 
ATOM   3665 N N   . GLY A 1 542  ? 139.764 93.547  80.434  1.00 138.33 ? 501  GLY A N   1 
ATOM   3666 C CA  . GLY A 1 542  ? 138.603 94.340  80.790  1.00 138.33 ? 501  GLY A CA  1 
ATOM   3667 C C   . GLY A 1 542  ? 138.755 95.790  80.369  1.00 138.33 ? 501  GLY A C   1 
ATOM   3668 O O   . GLY A 1 542  ? 139.417 96.122  79.380  1.00 138.33 ? 501  GLY A O   1 
ATOM   3669 N N   . GLU A 1 543  ? 138.124 96.676  81.143  1.00 150.03 ? 502  GLU A N   1 
ATOM   3670 C CA  . GLU A 1 543  ? 138.345 98.106  80.961  1.00 150.03 ? 502  GLU A CA  1 
ATOM   3671 C C   . GLU A 1 543  ? 139.726 98.518  81.454  1.00 150.03 ? 502  GLU A C   1 
ATOM   3672 O O   . GLU A 1 543  ? 140.305 99.483  80.944  1.00 150.03 ? 502  GLU A O   1 
ATOM   3673 C CB  . GLU A 1 543  ? 137.260 98.903  81.688  1.00 150.03 ? 502  GLU A CB  1 
ATOM   3674 C CG  . GLU A 1 543  ? 137.339 100.409 81.482  1.00 150.03 ? 502  GLU A CG  1 
ATOM   3675 C CD  . GLU A 1 543  ? 136.222 101.151 82.186  1.00 150.03 ? 502  GLU A CD  1 
ATOM   3676 O OE1 . GLU A 1 543  ? 135.353 100.487 82.789  1.00 150.03 ? 502  GLU A OE1 1 
ATOM   3677 O OE2 . GLU A 1 543  ? 136.212 102.400 82.137  1.00 150.03 ? 502  GLU A OE2 1 
ATOM   3678 N N   . ARG A 1 544  ? 140.269 97.791  82.432  1.00 153.89 ? 503  ARG A N   1 
ATOM   3679 C CA  . ARG A 1 544  ? 141.586 98.065  82.994  1.00 153.89 ? 503  ARG A CA  1 
ATOM   3680 C C   . ARG A 1 544  ? 142.700 97.352  82.235  1.00 153.89 ? 503  ARG A C   1 
ATOM   3681 O O   . ARG A 1 544  ? 143.758 97.062  82.811  1.00 153.89 ? 503  ARG A O   1 
ATOM   3682 C CB  . ARG A 1 544  ? 141.610 97.679  84.474  1.00 153.89 ? 503  ARG A CB  1 
ATOM   3683 C CG  . ARG A 1 544  ? 142.647 98.416  85.316  1.00 153.89 ? 503  ARG A CG  1 
ATOM   3684 C CD  . ARG A 1 544  ? 142.317 99.891  85.462  1.00 153.89 ? 503  ARG A CD  1 
ATOM   3685 N NE  . ARG A 1 544  ? 142.971 100.701 84.441  1.00 153.89 ? 503  ARG A NE  1 
ATOM   3686 C CZ  . ARG A 1 544  ? 142.841 102.016 84.333  1.00 153.89 ? 503  ARG A CZ  1 
ATOM   3687 N NH1 . ARG A 1 544  ? 142.095 102.708 85.178  1.00 153.89 ? 503  ARG A NH1 1 
ATOM   3688 N NH2 . ARG A 1 544  ? 143.479 102.653 83.356  1.00 153.89 ? 503  ARG A NH2 1 
ATOM   3689 N N   . GLY A 1 545  ? 142.481 97.046  80.959  1.00 158.48 ? 504  GLY A N   1 
ATOM   3690 C CA  . GLY A 1 545  ? 143.509 96.392  80.176  1.00 158.48 ? 504  GLY A CA  1 
ATOM   3691 C C   . GLY A 1 545  ? 144.751 97.251  80.039  1.00 158.48 ? 504  GLY A C   1 
ATOM   3692 O O   . GLY A 1 545  ? 144.693 98.480  80.011  1.00 158.48 ? 504  GLY A O   1 
ATOM   3693 N N   . LEU A 1 546  ? 145.896 96.581  79.952  1.00 166.10 ? 505  LEU A N   1 
ATOM   3694 C CA  . LEU A 1 546  ? 147.169 97.273  79.854  1.00 166.10 ? 505  LEU A CA  1 
ATOM   3695 C C   . LEU A 1 546  ? 147.271 98.005  78.518  1.00 166.10 ? 505  LEU A C   1 
ATOM   3696 O O   . LEU A 1 546  ? 146.366 97.966  77.679  1.00 166.10 ? 505  LEU A O   1 
ATOM   3697 C CB  . LEU A 1 546  ? 148.322 96.288  80.030  1.00 166.10 ? 505  LEU A CB  1 
ATOM   3698 C CG  . LEU A 1 546  ? 148.468 95.681  81.426  1.00 166.10 ? 505  LEU A CG  1 
ATOM   3699 C CD1 . LEU A 1 546  ? 149.753 94.882  81.524  1.00 166.10 ? 505  LEU A CD1 1 
ATOM   3700 C CD2 . LEU A 1 546  ? 148.427 96.766  82.492  1.00 166.10 ? 505  LEU A CD2 1 
ATOM   3701 N N   . GLN A 1 547  ? 148.394 98.693  78.324  1.00 170.53 ? 506  GLN A N   1 
ATOM   3702 C CA  . GLN A 1 547  ? 148.611 99.453  77.101  1.00 170.53 ? 506  GLN A CA  1 
ATOM   3703 C C   . GLN A 1 547  ? 148.602 98.528  75.893  1.00 170.53 ? 506  GLN A C   1 
ATOM   3704 O O   . GLN A 1 547  ? 149.510 97.709  75.717  1.00 170.53 ? 506  GLN A O   1 
ATOM   3705 C CB  . GLN A 1 547  ? 149.927 100.230 77.173  1.00 170.53 ? 506  GLN A CB  1 
ATOM   3706 C CG  . GLN A 1 547  ? 150.328 100.887 75.862  1.00 170.53 ? 506  GLN A CG  1 
ATOM   3707 C CD  . GLN A 1 547  ? 149.228 101.756 75.286  1.00 170.53 ? 506  GLN A CD  1 
ATOM   3708 O OE1 . GLN A 1 547  ? 148.731 101.502 74.189  1.00 170.53 ? 506  GLN A OE1 1 
ATOM   3709 N NE2 . GLN A 1 547  ? 148.841 102.790 76.024  1.00 170.53 ? 506  GLN A NE2 1 
ATOM   3710 N N   . LEU A 1 548  ? 147.572 98.647  75.063  1.00 167.27 ? 507  LEU A N   1 
ATOM   3711 C CA  . LEU A 1 548  ? 147.431 97.859  73.846  1.00 167.27 ? 507  LEU A CA  1 
ATOM   3712 C C   . LEU A 1 548  ? 147.367 98.829  72.674  1.00 167.27 ? 507  LEU A C   1 
ATOM   3713 O O   . LEU A 1 548  ? 146.345 99.491  72.465  1.00 167.27 ? 507  LEU A O   1 
ATOM   3714 C CB  . LEU A 1 548  ? 146.187 96.975  73.907  1.00 167.27 ? 507  LEU A CB  1 
ATOM   3715 C CG  . LEU A 1 548  ? 146.167 95.946  75.040  1.00 167.27 ? 507  LEU A CG  1 
ATOM   3716 C CD1 . LEU A 1 548  ? 144.946 95.050  74.927  1.00 167.27 ? 507  LEU A CD1 1 
ATOM   3717 C CD2 . LEU A 1 548  ? 147.442 95.116  75.039  1.00 167.27 ? 507  LEU A CD2 1 
ATOM   3718 N N   . SER A 1 549  ? 148.454 98.908  71.913  1.00 163.68 ? 508  SER A N   1 
ATOM   3719 C CA  . SER A 1 549  ? 148.571 99.863  70.821  1.00 163.68 ? 508  SER A CA  1 
ATOM   3720 C C   . SER A 1 549  ? 147.913 99.377  69.540  1.00 163.68 ? 508  SER A C   1 
ATOM   3721 O O   . SER A 1 549  ? 147.968 100.079 68.526  1.00 163.68 ? 508  SER A O   1 
ATOM   3722 C CB  . SER A 1 549  ? 150.046 100.178 70.554  1.00 163.68 ? 508  SER A CB  1 
ATOM   3723 O OG  . SER A 1 549  ? 150.740 99.027  70.106  1.00 163.68 ? 508  SER A OG  1 
ATOM   3724 N N   . GLY A 1 550  ? 147.300 98.198  69.559  1.00 154.94 ? 509  GLY A N   1 
ATOM   3725 C CA  . GLY A 1 550  ? 146.671 97.655  68.375  1.00 154.94 ? 509  GLY A CA  1 
ATOM   3726 C C   . GLY A 1 550  ? 147.382 96.422  67.864  1.00 154.94 ? 509  GLY A C   1 
ATOM   3727 O O   . GLY A 1 550  ? 146.737 95.465  67.430  1.00 154.94 ? 509  GLY A O   1 
ATOM   3728 N N   . GLY A 1 551  ? 148.715 96.433  67.911  1.00 150.48 ? 510  GLY A N   1 
ATOM   3729 C CA  . GLY A 1 551  ? 149.470 95.277  67.458  1.00 150.48 ? 510  GLY A CA  1 
ATOM   3730 C C   . GLY A 1 551  ? 149.276 94.059  68.342  1.00 150.48 ? 510  GLY A C   1 
ATOM   3731 O O   . GLY A 1 551  ? 149.117 92.940  67.846  1.00 150.48 ? 510  GLY A O   1 
ATOM   3732 N N   . GLN A 1 552  ? 149.288 94.257  69.662  1.00 150.19 ? 511  GLN A N   1 
ATOM   3733 C CA  . GLN A 1 552  ? 149.107 93.140  70.586  1.00 150.19 ? 511  GLN A CA  1 
ATOM   3734 C C   . GLN A 1 552  ? 147.743 92.490  70.398  1.00 150.19 ? 511  GLN A C   1 
ATOM   3735 O O   . GLN A 1 552  ? 147.641 91.270  70.206  1.00 150.19 ? 511  GLN A O   1 
ATOM   3736 C CB  . GLN A 1 552  ? 149.269 93.627  72.028  1.00 150.19 ? 511  GLN A CB  1 
ATOM   3737 C CG  . GLN A 1 552  ? 150.705 93.787  72.496  1.00 150.19 ? 511  GLN A CG  1 
ATOM   3738 C CD  . GLN A 1 552  ? 151.489 92.497  72.418  1.00 150.19 ? 511  GLN A CD  1 
ATOM   3739 O OE1 . GLN A 1 552  ? 151.032 91.448  72.871  1.00 150.19 ? 511  GLN A OE1 1 
ATOM   3740 N NE2 . GLN A 1 552  ? 152.689 92.567  71.853  1.00 150.19 ? 511  GLN A NE2 1 
ATOM   3741 N N   . LYS A 1 553  ? 146.682 93.296  70.438  1.00 140.64 ? 512  LYS A N   1 
ATOM   3742 C CA  . LYS A 1 553  ? 145.339 92.755  70.275  1.00 140.64 ? 512  LYS A CA  1 
ATOM   3743 C C   . LYS A 1 553  ? 145.144 92.169  68.884  1.00 140.64 ? 512  LYS A C   1 
ATOM   3744 O O   . LYS A 1 553  ? 144.431 91.170  68.727  1.00 140.64 ? 512  LYS A O   1 
ATOM   3745 C CB  . LYS A 1 553  ? 144.299 93.837  70.569  1.00 140.64 ? 512  LYS A CB  1 
ATOM   3746 C CG  . LYS A 1 553  ? 144.327 95.024  69.625  1.00 140.64 ? 512  LYS A CG  1 
ATOM   3747 C CD  . LYS A 1 553  ? 143.724 96.256  70.279  1.00 140.64 ? 512  LYS A CD  1 
ATOM   3748 C CE  . LYS A 1 553  ? 142.208 96.166  70.350  1.00 140.64 ? 512  LYS A CE  1 
ATOM   3749 N NZ  . LYS A 1 553  ? 141.570 96.310  69.013  1.00 140.64 ? 512  LYS A NZ  1 
ATOM   3750 N N   . GLN A 1 554  ? 145.783 92.752  67.869  1.00 140.51 ? 513  GLN A N   1 
ATOM   3751 C CA  . GLN A 1 554  ? 145.676 92.195  66.529  1.00 140.51 ? 513  GLN A CA  1 
ATOM   3752 C C   . GLN A 1 554  ? 146.281 90.797  66.496  1.00 140.51 ? 513  GLN A C   1 
ATOM   3753 O O   . GLN A 1 554  ? 145.656 89.849  66.009  1.00 140.51 ? 513  GLN A O   1 
ATOM   3754 C CB  . GLN A 1 554  ? 146.381 93.099  65.521  1.00 140.51 ? 513  GLN A CB  1 
ATOM   3755 C CG  . GLN A 1 554  ? 146.082 92.787  64.064  1.00 140.51 ? 513  GLN A CG  1 
ATOM   3756 C CD  . GLN A 1 554  ? 144.609 92.495  63.824  1.00 140.51 ? 513  GLN A CD  1 
ATOM   3757 O OE1 . GLN A 1 554  ? 144.163 91.352  63.868  1.00 140.51 ? 513  GLN A OE1 1 
ATOM   3758 N NE2 . GLN A 1 554  ? 143.843 93.547  63.562  1.00 140.51 ? 513  GLN A NE2 1 
ATOM   3759 N N   . ARG A 1 555  ? 147.487 90.649  67.055  1.00 146.52 ? 514  ARG A N   1 
ATOM   3760 C CA  . ARG A 1 555  ? 148.141 89.344  67.089  1.00 146.52 ? 514  ARG A CA  1 
ATOM   3761 C C   . ARG A 1 555  ? 147.302 88.336  67.860  1.00 146.52 ? 514  ARG A C   1 
ATOM   3762 O O   . ARG A 1 555  ? 147.208 87.164  67.469  1.00 146.52 ? 514  ARG A O   1 
ATOM   3763 C CB  . ARG A 1 555  ? 149.531 89.470  67.713  1.00 146.52 ? 514  ARG A CB  1 
ATOM   3764 C CG  . ARG A 1 555  ? 150.612 89.968  66.763  1.00 146.52 ? 514  ARG A CG  1 
ATOM   3765 C CD  . ARG A 1 555  ? 151.965 90.073  67.463  1.00 146.52 ? 514  ARG A CD  1 
ATOM   3766 N NE  . ARG A 1 555  ? 152.134 89.066  68.504  1.00 146.52 ? 514  ARG A NE  1 
ATOM   3767 C CZ  . ARG A 1 555  ? 152.986 88.053  68.436  1.00 146.52 ? 514  ARG A CZ  1 
ATOM   3768 N NH1 . ARG A 1 555  ? 153.776 87.885  67.389  1.00 146.52 ? 514  ARG A NH1 1 
ATOM   3769 N NH2 . ARG A 1 555  ? 153.046 87.186  69.442  1.00 146.52 ? 514  ARG A NH2 1 
ATOM   3770 N N   . ILE A 1 556  ? 146.678 88.776  68.953  1.00 134.89 ? 515  ILE A N   1 
ATOM   3771 C CA  . ILE A 1 556  ? 145.770 87.904  69.695  1.00 134.89 ? 515  ILE A CA  1 
ATOM   3772 C C   . ILE A 1 556  ? 144.626 87.442  68.796  1.00 134.89 ? 515  ILE A C   1 
ATOM   3773 O O   . ILE A 1 556  ? 144.224 86.271  68.817  1.00 134.89 ? 515  ILE A O   1 
ATOM   3774 C CB  . ILE A 1 556  ? 145.247 88.622  70.952  1.00 134.89 ? 515  ILE A CB  1 
ATOM   3775 C CG1 . ILE A 1 556  ? 146.403 88.939  71.904  1.00 134.89 ? 515  ILE A CG1 1 
ATOM   3776 C CG2 . ILE A 1 556  ? 144.202 87.782  71.655  1.00 134.89 ? 515  ILE A CG2 1 
ATOM   3777 C CD1 . ILE A 1 556  ? 146.021 89.864  73.032  1.00 134.89 ? 515  ILE A CD1 1 
ATOM   3778 N N   . ALA A 1 557  ? 144.082 88.363  67.997  1.00 130.68 ? 516  ALA A N   1 
ATOM   3779 C CA  . ALA A 1 557  ? 142.984 88.011  67.102  1.00 130.68 ? 516  ALA A CA  1 
ATOM   3780 C C   . ALA A 1 557  ? 143.413 86.974  66.067  1.00 130.68 ? 516  ALA A C   1 
ATOM   3781 O O   . ALA A 1 557  ? 142.702 85.985  65.842  1.00 130.68 ? 516  ALA A O   1 
ATOM   3782 C CB  . ALA A 1 557  ? 142.443 89.264  66.417  1.00 130.68 ? 516  ALA A CB  1 
ATOM   3783 N N   . ILE A 1 558  ? 144.577 87.165  65.439  1.00 129.19 ? 517  ILE A N   1 
ATOM   3784 C CA  . ILE A 1 558  ? 144.997 86.170  64.451  1.00 129.19 ? 517  ILE A CA  1 
ATOM   3785 C C   . ILE A 1 558  ? 145.299 84.835  65.130  1.00 129.19 ? 517  ILE A C   1 
ATOM   3786 O O   . ILE A 1 558  ? 145.084 83.772  64.540  1.00 129.19 ? 517  ILE A O   1 
ATOM   3787 C CB  . ILE A 1 558  ? 146.179 86.634  63.568  1.00 129.19 ? 517  ILE A CB  1 
ATOM   3788 C CG1 . ILE A 1 558  ? 145.849 87.848  62.702  1.00 129.19 ? 517  ILE A CG1 1 
ATOM   3789 C CG2 . ILE A 1 558  ? 146.527 85.584  62.546  1.00 129.19 ? 517  ILE A CG2 1 
ATOM   3790 C CD1 . ILE A 1 558  ? 146.106 89.145  63.298  1.00 129.19 ? 517  ILE A CD1 1 
ATOM   3791 N N   . ALA A 1 559  ? 145.801 84.856  66.368  1.00 127.85 ? 518  ALA A N   1 
ATOM   3792 C CA  . ALA A 1 559  ? 146.058 83.595  67.068  1.00 127.85 ? 518  ALA A CA  1 
ATOM   3793 C C   . ALA A 1 559  ? 144.767 82.828  67.327  1.00 127.85 ? 518  ALA A C   1 
ATOM   3794 O O   . ALA A 1 559  ? 144.673 81.619  67.041  1.00 127.85 ? 518  ALA A O   1 
ATOM   3795 C CB  . ALA A 1 559  ? 146.795 83.862  68.379  1.00 127.85 ? 518  ALA A CB  1 
ATOM   3796 N N   . ARG A 1 560  ? 143.758 83.523  67.858  1.00 116.58 ? 519  ARG A N   1 
ATOM   3797 C CA  . ARG A 1 560  ? 142.438 82.922  67.999  1.00 116.58 ? 519  ARG A CA  1 
ATOM   3798 C C   . ARG A 1 560  ? 141.941 82.401  66.660  1.00 116.58 ? 519  ARG A C   1 
ATOM   3799 O O   . ARG A 1 560  ? 141.255 81.376  66.596  1.00 116.58 ? 519  ARG A O   1 
ATOM   3800 C CB  . ARG A 1 560  ? 141.461 83.942  68.585  1.00 116.58 ? 519  ARG A CB  1 
ATOM   3801 C CG  . ARG A 1 560  ? 140.011 83.505  68.579  1.00 116.58 ? 519  ARG A CG  1 
ATOM   3802 C CD  . ARG A 1 560  ? 139.141 84.494  69.326  1.00 116.58 ? 519  ARG A CD  1 
ATOM   3803 N NE  . ARG A 1 560  ? 139.161 85.817  68.717  1.00 116.58 ? 519  ARG A NE  1 
ATOM   3804 C CZ  . ARG A 1 560  ? 138.882 86.940  69.364  1.00 116.58 ? 519  ARG A CZ  1 
ATOM   3805 N NH1 . ARG A 1 560  ? 138.571 86.938  70.648  1.00 116.58 ? 519  ARG A NH1 1 
ATOM   3806 N NH2 . ARG A 1 560  ? 138.920 88.094  68.706  1.00 116.58 ? 519  ARG A NH2 1 
ATOM   3807 N N   . ALA A 1 561  ? 142.294 83.090  65.574  1.00 124.53 ? 520  ALA A N   1 
ATOM   3808 C CA  . ALA A 1 561  ? 141.934 82.602  64.249  1.00 124.53 ? 520  ALA A CA  1 
ATOM   3809 C C   . ALA A 1 561  ? 142.644 81.292  63.915  1.00 124.53 ? 520  ALA A C   1 
ATOM   3810 O O   . ALA A 1 561  ? 142.014 80.360  63.402  1.00 124.53 ? 520  ALA A O   1 
ATOM   3811 C CB  . ALA A 1 561  ? 142.238 83.665  63.196  1.00 124.53 ? 520  ALA A CB  1 
ATOM   3812 N N   . MET A 1 562  ? 143.954 81.192  64.185  1.00 128.93 ? 521  MET A N   1 
ATOM   3813 C CA  . MET A 1 562  ? 144.644 79.975  63.759  1.00 128.93 ? 521  MET A CA  1 
ATOM   3814 C C   . MET A 1 562  ? 144.268 78.778  64.614  1.00 128.93 ? 521  MET A C   1 
ATOM   3815 O O   . MET A 1 562  ? 144.515 77.638  64.205  1.00 128.93 ? 521  MET A O   1 
ATOM   3816 C CB  . MET A 1 562  ? 146.180 80.048  63.743  1.00 128.93 ? 521  MET A CB  1 
ATOM   3817 C CG  . MET A 1 562  ? 146.861 80.935  62.713  1.00 128.93 ? 521  MET A CG  1 
ATOM   3818 S SD  . MET A 1 562  ? 148.408 81.660  63.305  1.00 128.93 ? 521  MET A SD  1 
ATOM   3819 C CE  . MET A 1 562  ? 147.962 83.074  64.257  1.00 128.93 ? 521  MET A CE  1 
ATOM   3820 N N   . LEU A 1 563  ? 143.703 78.989  65.807  1.00 123.94 ? 522  LEU A N   1 
ATOM   3821 C CA  . LEU A 1 563  ? 143.212 77.804  66.509  1.00 123.94 ? 522  LEU A CA  1 
ATOM   3822 C C   . LEU A 1 563  ? 142.132 77.066  65.726  1.00 123.94 ? 522  LEU A C   1 
ATOM   3823 O O   . LEU A 1 563  ? 141.919 75.873  65.966  1.00 123.94 ? 522  LEU A O   1 
ATOM   3824 C CB  . LEU A 1 563  ? 142.687 78.134  67.899  1.00 123.94 ? 522  LEU A CB  1 
ATOM   3825 C CG  . LEU A 1 563  ? 143.724 78.567  68.924  1.00 123.94 ? 522  LEU A CG  1 
ATOM   3826 C CD1 . LEU A 1 563  ? 143.005 78.939  70.183  1.00 123.94 ? 522  LEU A CD1 1 
ATOM   3827 C CD2 . LEU A 1 563  ? 144.698 77.437  69.184  1.00 123.94 ? 522  LEU A CD2 1 
ATOM   3828 N N   . LYS A 1 564  ? 141.446 77.737  64.800  1.00 123.38 ? 523  LYS A N   1 
ATOM   3829 C CA  . LYS A 1 564  ? 140.538 77.069  63.868  1.00 123.38 ? 523  LYS A CA  1 
ATOM   3830 C C   . LYS A 1 564  ? 141.346 76.715  62.622  1.00 123.38 ? 523  LYS A C   1 
ATOM   3831 O O   . LYS A 1 564  ? 141.325 77.409  61.605  1.00 123.38 ? 523  LYS A O   1 
ATOM   3832 C CB  . LYS A 1 564  ? 139.338 77.951  63.549  1.00 123.38 ? 523  LYS A CB  1 
ATOM   3833 C CG  . LYS A 1 564  ? 138.349 78.078  64.691  1.00 123.38 ? 523  LYS A CG  1 
ATOM   3834 C CD  . LYS A 1 564  ? 137.671 79.433  64.676  1.00 123.38 ? 523  LYS A CD  1 
ATOM   3835 C CE  . LYS A 1 564  ? 136.470 79.427  63.751  1.00 123.38 ? 523  LYS A CE  1 
ATOM   3836 N NZ  . LYS A 1 564  ? 136.033 80.804  63.396  1.00 123.38 ? 523  LYS A NZ  1 
ATOM   3837 N N   . ASN A 1 565  ? 142.071 75.602  62.722  1.00 132.85 ? 524  ASN A N   1 
ATOM   3838 C CA  . ASN A 1 565  ? 143.082 75.259  61.722  1.00 132.85 ? 524  ASN A CA  1 
ATOM   3839 C C   . ASN A 1 565  ? 142.528 75.092  60.310  1.00 132.85 ? 524  ASN A C   1 
ATOM   3840 O O   . ASN A 1 565  ? 143.060 75.736  59.389  1.00 132.85 ? 524  ASN A O   1 
ATOM   3841 C CB  . ASN A 1 565  ? 143.819 73.995  62.188  1.00 132.85 ? 524  ASN A CB  1 
ATOM   3842 C CG  . ASN A 1 565  ? 145.028 73.663  61.332  1.00 132.85 ? 524  ASN A CG  1 
ATOM   3843 O OD1 . ASN A 1 565  ? 145.331 74.348  60.359  1.00 132.85 ? 524  ASN A OD1 1 
ATOM   3844 N ND2 . ASN A 1 565  ? 145.726 72.594  61.695  1.00 132.85 ? 524  ASN A ND2 1 
ATOM   3845 N N   . PRO A 1 566  ? 141.501 74.284  60.055  1.00 134.56 ? 525  PRO A N   1 
ATOM   3846 C CA  . PRO A 1 566  ? 141.186 73.911  58.671  1.00 134.56 ? 525  PRO A CA  1 
ATOM   3847 C C   . PRO A 1 566  ? 140.454 75.010  57.908  1.00 134.56 ? 525  PRO A C   1 
ATOM   3848 O O   . PRO A 1 566  ? 140.045 76.036  58.452  1.00 134.56 ? 525  PRO A O   1 
ATOM   3849 C CB  . PRO A 1 566  ? 140.294 72.678  58.838  1.00 134.56 ? 525  PRO A CB  1 
ATOM   3850 C CG  . PRO A 1 566  ? 139.607 72.910  60.123  1.00 134.56 ? 525  PRO A CG  1 
ATOM   3851 C CD  . PRO A 1 566  ? 140.609 73.596  61.008  1.00 134.56 ? 525  PRO A CD  1 
ATOM   3852 N N   . ALA A 1 567  ? 140.325 74.766  56.601  1.00 135.90 ? 526  ALA A N   1 
ATOM   3853 C CA  . ALA A 1 567  ? 139.406 75.469  55.711  1.00 135.90 ? 526  ALA A CA  1 
ATOM   3854 C C   . ALA A 1 567  ? 139.728 76.944  55.507  1.00 135.90 ? 526  ALA A C   1 
ATOM   3855 O O   . ALA A 1 567  ? 140.827 77.408  55.820  1.00 135.90 ? 526  ALA A O   1 
ATOM   3856 C CB  . ALA A 1 567  ? 137.972 75.325  56.223  1.00 135.90 ? 526  ALA A CB  1 
ATOM   3857 N N   . ILE A 1 568  ? 138.748 77.679  54.977  1.00 133.21 ? 527  ILE A N   1 
ATOM   3858 C CA  . ILE A 1 568  ? 138.960 79.042  54.510  1.00 133.21 ? 527  ILE A CA  1 
ATOM   3859 C C   . ILE A 1 568  ? 139.208 79.985  55.682  1.00 133.21 ? 527  ILE A C   1 
ATOM   3860 O O   . ILE A 1 568  ? 138.736 79.767  56.805  1.00 133.21 ? 527  ILE A O   1 
ATOM   3861 C CB  . ILE A 1 568  ? 137.749 79.495  53.671  1.00 133.21 ? 527  ILE A CB  1 
ATOM   3862 C CG1 . ILE A 1 568  ? 138.033 80.816  52.954  1.00 133.21 ? 527  ILE A CG1 1 
ATOM   3863 C CG2 . ILE A 1 568  ? 136.504 79.597  54.532  1.00 133.21 ? 527  ILE A CG2 1 
ATOM   3864 C CD1 . ILE A 1 568  ? 137.027 81.151  51.878  1.00 133.21 ? 527  ILE A CD1 1 
ATOM   3865 N N   . LEU A 1 569  ? 139.974 81.041  55.418  1.00 128.21 ? 528  LEU A N   1 
ATOM   3866 C CA  . LEU A 1 569  ? 140.215 82.114  56.370  1.00 128.21 ? 528  LEU A CA  1 
ATOM   3867 C C   . LEU A 1 569  ? 139.989 83.434  55.649  1.00 128.21 ? 528  LEU A C   1 
ATOM   3868 O O   . LEU A 1 569  ? 140.559 83.661  54.579  1.00 128.21 ? 528  LEU A O   1 
ATOM   3869 C CB  . LEU A 1 569  ? 141.636 82.031  56.945  1.00 128.21 ? 528  LEU A CB  1 
ATOM   3870 C CG  . LEU A 1 569  ? 142.063 82.948  58.099  1.00 128.21 ? 528  LEU A CG  1 
ATOM   3871 C CD1 . LEU A 1 569  ? 143.173 82.291  58.905  1.00 128.21 ? 528  LEU A CD1 1 
ATOM   3872 C CD2 . LEU A 1 569  ? 142.523 84.305  57.613  1.00 128.21 ? 528  LEU A CD2 1 
ATOM   3873 N N   . LEU A 1 570  ? 139.160 84.295  56.231  1.00 127.19 ? 529  LEU A N   1 
ATOM   3874 C CA  . LEU A 1 570  ? 138.780 85.556  55.611  1.00 127.19 ? 529  LEU A CA  1 
ATOM   3875 C C   . LEU A 1 570  ? 139.573 86.704  56.220  1.00 127.19 ? 529  LEU A C   1 
ATOM   3876 O O   . LEU A 1 570  ? 139.717 86.794  57.441  1.00 127.19 ? 529  LEU A O   1 
ATOM   3877 C CB  . LEU A 1 570  ? 137.281 85.814  55.781  1.00 127.19 ? 529  LEU A CB  1 
ATOM   3878 C CG  . LEU A 1 570  ? 136.346 84.693  55.324  1.00 127.19 ? 529  LEU A CG  1 
ATOM   3879 C CD1 . LEU A 1 570  ? 134.896 85.073  55.562  1.00 127.19 ? 529  LEU A CD1 1 
ATOM   3880 C CD2 . LEU A 1 570  ? 136.580 84.358  53.862  1.00 127.19 ? 529  LEU A CD2 1 
ATOM   3881 N N   . LEU A 1 571  ? 140.082 87.581  55.362  1.00 138.28 ? 530  LEU A N   1 
ATOM   3882 C CA  . LEU A 1 571  ? 140.889 88.718  55.776  1.00 138.28 ? 530  LEU A CA  1 
ATOM   3883 C C   . LEU A 1 571  ? 140.109 90.010  55.569  1.00 138.28 ? 530  LEU A C   1 
ATOM   3884 O O   . LEU A 1 571  ? 138.969 90.010  55.099  1.00 138.28 ? 530  LEU A O   1 
ATOM   3885 C CB  . LEU A 1 571  ? 142.202 88.777  54.992  1.00 138.28 ? 530  LEU A CB  1 
ATOM   3886 C CG  . LEU A 1 571  ? 143.371 87.853  55.320  1.00 138.28 ? 530  LEU A CG  1 
ATOM   3887 C CD1 . LEU A 1 571  ? 143.069 86.431  54.894  1.00 138.28 ? 530  LEU A CD1 1 
ATOM   3888 C CD2 . LEU A 1 571  ? 144.635 88.355  54.649  1.00 138.28 ? 530  LEU A CD2 1 
ATOM   3889 N N   . ASP A 1 572  ? 140.751 91.120  55.925  1.00 143.95 ? 531  ASP A N   1 
ATOM   3890 C CA  . ASP A 1 572  ? 140.305 92.458  55.549  1.00 143.95 ? 531  ASP A CA  1 
ATOM   3891 C C   . ASP A 1 572  ? 141.422 93.437  55.901  1.00 143.95 ? 531  ASP A C   1 
ATOM   3892 O O   . ASP A 1 572  ? 142.447 93.059  56.475  1.00 143.95 ? 531  ASP A O   1 
ATOM   3893 C CB  . ASP A 1 572  ? 138.976 92.834  56.212  1.00 143.95 ? 531  ASP A CB  1 
ATOM   3894 C CG  . ASP A 1 572  ? 139.057 92.887  57.722  1.00 143.95 ? 531  ASP A CG  1 
ATOM   3895 O OD1 . ASP A 1 572  ? 140.128 92.596  58.292  1.00 143.95 ? 531  ASP A OD1 1 
ATOM   3896 O OD2 . ASP A 1 572  ? 138.028 93.228  58.340  1.00 143.95 ? 531  ASP A OD2 1 
ATOM   3897 N N   . GLU A 1 573  ? 141.211 94.701  55.544  1.00 157.86 ? 532  GLU A N   1 
ATOM   3898 C CA  . GLU A 1 573  ? 142.219 95.725  55.780  1.00 157.86 ? 532  GLU A CA  1 
ATOM   3899 C C   . GLU A 1 573  ? 142.377 95.998  57.271  1.00 157.86 ? 532  GLU A C   1 
ATOM   3900 O O   . GLU A 1 573  ? 141.401 95.999  58.027  1.00 157.86 ? 532  GLU A O   1 
ATOM   3901 C CB  . GLU A 1 573  ? 141.839 97.013  55.049  1.00 157.86 ? 532  GLU A CB  1 
ATOM   3902 C CG  . GLU A 1 573  ? 142.825 98.153  55.245  1.00 157.86 ? 532  GLU A CG  1 
ATOM   3903 C CD  . GLU A 1 573  ? 142.201 99.512  55.003  1.00 157.86 ? 532  GLU A CD  1 
ATOM   3904 O OE1 . GLU A 1 573  ? 141.018 99.564  54.609  1.00 157.86 ? 532  GLU A OE1 1 
ATOM   3905 O OE2 . GLU A 1 573  ? 142.892 100.531 55.216  1.00 157.86 ? 532  GLU A OE2 1 
ATOM   3906 N N   . ALA A 1 574  ? 143.617 96.218  57.693  1.00 172.64 ? 533  ALA A N   1 
ATOM   3907 C CA  . ALA A 1 574  ? 143.911 96.615  59.059  1.00 172.64 ? 533  ALA A CA  1 
ATOM   3908 C C   . ALA A 1 574  ? 144.057 98.134  59.125  1.00 172.64 ? 533  ALA A C   1 
ATOM   3909 O O   . ALA A 1 574  ? 143.764 98.850  58.165  1.00 172.64 ? 533  ALA A O   1 
ATOM   3910 C CB  . ALA A 1 574  ? 145.161 95.894  59.561  1.00 172.64 ? 533  ALA A CB  1 
ATOM   3911 N N   . THR A 1 575  ? 144.505 98.646  60.267  1.00 187.76 ? 534  THR A N   1 
ATOM   3912 C CA  . THR A 1 575  ? 144.767 100.072 60.386  1.00 187.76 ? 534  THR A CA  1 
ATOM   3913 C C   . THR A 1 575  ? 145.932 100.475 59.488  1.00 187.76 ? 534  THR A C   1 
ATOM   3914 O O   . THR A 1 575  ? 146.810 99.670  59.169  1.00 187.76 ? 534  THR A O   1 
ATOM   3915 C CB  . THR A 1 575  ? 145.073 100.448 61.837  1.00 187.76 ? 534  THR A CB  1 
ATOM   3916 O OG1 . THR A 1 575  ? 145.363 101.850 61.918  1.00 187.76 ? 534  THR A OG1 1 
ATOM   3917 C CG2 . THR A 1 575  ? 146.265 99.659  62.355  1.00 187.76 ? 534  THR A CG2 1 
ATOM   3918 N N   . SER A 1 576  ? 145.920 101.741 59.065  1.00 194.41 ? 535  SER A N   1 
ATOM   3919 C CA  . SER A 1 576  ? 146.969 102.229 58.176  1.00 194.41 ? 535  SER A CA  1 
ATOM   3920 C C   . SER A 1 576  ? 148.331 102.207 58.859  1.00 194.41 ? 535  SER A C   1 
ATOM   3921 O O   . SER A 1 576  ? 149.339 101.848 58.239  1.00 194.41 ? 535  SER A O   1 
ATOM   3922 C CB  . SER A 1 576  ? 146.630 103.639 57.691  1.00 194.41 ? 535  SER A CB  1 
ATOM   3923 O OG  . SER A 1 576  ? 145.503 103.622 56.832  1.00 194.41 ? 535  SER A OG  1 
ATOM   3924 N N   . ALA A 1 577  ? 148.383 102.586 60.136  1.00 191.77 ? 536  ALA A N   1 
ATOM   3925 C CA  . ALA A 1 577  ? 149.639 102.652 60.882  1.00 191.77 ? 536  ALA A CA  1 
ATOM   3926 C C   . ALA A 1 577  ? 149.781 101.385 61.720  1.00 191.77 ? 536  ALA A C   1 
ATOM   3927 O O   . ALA A 1 577  ? 149.464 101.346 62.907  1.00 191.77 ? 536  ALA A O   1 
ATOM   3928 C CB  . ALA A 1 577  ? 149.685 103.911 61.741  1.00 191.77 ? 536  ALA A CB  1 
ATOM   3929 N N   . LEU A 1 578  ? 150.276 100.331 61.076  1.00 183.19 ? 537  LEU A N   1 
ATOM   3930 C CA  . LEU A 1 578  ? 150.517 99.055  61.731  1.00 183.19 ? 537  LEU A CA  1 
ATOM   3931 C C   . LEU A 1 578  ? 151.894 98.532  61.347  1.00 183.19 ? 537  LEU A C   1 
ATOM   3932 O O   . LEU A 1 578  ? 152.349 98.711  60.215  1.00 183.19 ? 537  LEU A O   1 
ATOM   3933 C CB  . LEU A 1 578  ? 149.443 98.022  61.364  1.00 183.19 ? 537  LEU A CB  1 
ATOM   3934 C CG  . LEU A 1 578  ? 149.158 96.937  62.405  1.00 183.19 ? 537  LEU A CG  1 
ATOM   3935 C CD1 . LEU A 1 578  ? 148.928 97.552  63.778  1.00 183.19 ? 537  LEU A CD1 1 
ATOM   3936 C CD2 . LEU A 1 578  ? 147.964 96.093  61.985  1.00 183.19 ? 537  LEU A CD2 1 
ATOM   3937 N N   . ASP A 1 579  ? 152.548 97.879  62.303  1.00 173.79 ? 538  ASP A N   1 
ATOM   3938 C CA  . ASP A 1 579  ? 153.889 97.363  62.078  1.00 173.79 ? 538  ASP A CA  1 
ATOM   3939 C C   . ASP A 1 579  ? 153.857 96.165  61.132  1.00 173.79 ? 538  ASP A C   1 
ATOM   3940 O O   . ASP A 1 579  ? 152.843 95.479  60.981  1.00 173.79 ? 538  ASP A O   1 
ATOM   3941 C CB  . ASP A 1 579  ? 154.546 96.978  63.404  1.00 173.79 ? 538  ASP A CB  1 
ATOM   3942 C CG  . ASP A 1 579  ? 154.052 95.648  63.935  1.00 173.79 ? 538  ASP A CG  1 
ATOM   3943 O OD1 . ASP A 1 579  ? 152.830 95.398  63.881  1.00 173.79 ? 538  ASP A OD1 1 
ATOM   3944 O OD2 . ASP A 1 579  ? 154.887 94.855  64.412  1.00 173.79 ? 538  ASP A OD2 1 
ATOM   3945 N N   . SER A 1 580  ? 155.001 95.916  60.490  1.00 172.10 ? 539  SER A N   1 
ATOM   3946 C CA  . SER A 1 580  ? 155.077 94.882  59.466  1.00 172.10 ? 539  SER A CA  1 
ATOM   3947 C C   . SER A 1 580  ? 155.084 93.473  60.044  1.00 172.10 ? 539  SER A C   1 
ATOM   3948 O O   . SER A 1 580  ? 154.865 92.514  59.297  1.00 172.10 ? 539  SER A O   1 
ATOM   3949 C CB  . SER A 1 580  ? 156.326 95.090  58.607  1.00 172.10 ? 539  SER A CB  1 
ATOM   3950 O OG  . SER A 1 580  ? 157.478 95.252  59.417  1.00 172.10 ? 539  SER A OG  1 
ATOM   3951 N N   . GLU A 1 581  ? 155.344 93.320  61.344  1.00 167.67 ? 540  GLU A N   1 
ATOM   3952 C CA  . GLU A 1 581  ? 155.349 91.987  61.938  1.00 167.67 ? 540  GLU A CA  1 
ATOM   3953 C C   . GLU A 1 581  ? 153.963 91.354  61.884  1.00 167.67 ? 540  GLU A C   1 
ATOM   3954 O O   . GLU A 1 581  ? 153.826 90.168  61.558  1.00 167.67 ? 540  GLU A O   1 
ATOM   3955 C CB  . GLU A 1 581  ? 155.865 92.056  63.375  1.00 167.67 ? 540  GLU A CB  1 
ATOM   3956 C CG  . GLU A 1 581  ? 156.600 90.809  63.838  1.00 167.67 ? 540  GLU A CG  1 
ATOM   3957 C CD  . GLU A 1 581  ? 155.695 89.828  64.553  1.00 167.67 ? 540  GLU A CD  1 
ATOM   3958 O OE1 . GLU A 1 581  ? 154.683 90.269  65.134  1.00 167.67 ? 540  GLU A OE1 1 
ATOM   3959 O OE2 . GLU A 1 581  ? 155.994 88.615  64.535  1.00 167.67 ? 540  GLU A OE2 1 
ATOM   3960 N N   . SER A 1 582  ? 152.922 92.132  62.186  1.00 168.19 ? 541  SER A N   1 
ATOM   3961 C CA  . SER A 1 582  ? 151.562 91.616  62.073  1.00 168.19 ? 541  SER A CA  1 
ATOM   3962 C C   . SER A 1 582  ? 151.235 91.244  60.634  1.00 168.19 ? 541  SER A C   1 
ATOM   3963 O O   . SER A 1 582  ? 150.595 90.218  60.380  1.00 168.19 ? 541  SER A O   1 
ATOM   3964 C CB  . SER A 1 582  ? 150.561 92.646  62.596  1.00 168.19 ? 541  SER A CB  1 
ATOM   3965 O OG  . SER A 1 582  ? 150.249 93.601  61.599  1.00 168.19 ? 541  SER A OG  1 
ATOM   3966 N N   . GLU A 1 583  ? 151.668 92.069  59.677  1.00 168.34 ? 542  GLU A N   1 
ATOM   3967 C CA  . GLU A 1 583  ? 151.389 91.783  58.274  1.00 168.34 ? 542  GLU A CA  1 
ATOM   3968 C C   . GLU A 1 583  ? 152.090 90.512  57.812  1.00 168.34 ? 542  GLU A C   1 
ATOM   3969 O O   . GLU A 1 583  ? 151.509 89.712  57.073  1.00 168.34 ? 542  GLU A O   1 
ATOM   3970 C CB  . GLU A 1 583  ? 151.790 92.973  57.404  1.00 168.34 ? 542  GLU A CB  1 
ATOM   3971 C CG  . GLU A 1 583  ? 150.772 94.103  57.415  1.00 168.34 ? 542  GLU A CG  1 
ATOM   3972 C CD  . GLU A 1 583  ? 151.411 95.473  57.315  1.00 168.34 ? 542  GLU A CD  1 
ATOM   3973 O OE1 . GLU A 1 583  ? 151.113 96.198  56.344  1.00 168.34 ? 542  GLU A OE1 1 
ATOM   3974 O OE2 . GLU A 1 583  ? 152.207 95.825  58.210  1.00 168.34 ? 542  GLU A OE2 1 
ATOM   3975 N N   . LYS A 1 584  ? 153.336 90.297  58.241  1.00 164.82 ? 543  LYS A N   1 
ATOM   3976 C CA  . LYS A 1 584  ? 154.023 89.072  57.838  1.00 164.82 ? 543  LYS A CA  1 
ATOM   3977 C C   . LYS A 1 584  ? 153.437 87.850  58.534  1.00 164.82 ? 543  LYS A C   1 
ATOM   3978 O O   . LYS A 1 584  ? 153.392 86.765  57.941  1.00 164.82 ? 543  LYS A O   1 
ATOM   3979 C CB  . LYS A 1 584  ? 155.529 89.189  58.095  1.00 164.82 ? 543  LYS A CB  1 
ATOM   3980 C CG  . LYS A 1 584  ? 155.957 89.246  59.552  1.00 164.82 ? 543  LYS A CG  1 
ATOM   3981 C CD  . LYS A 1 584  ? 156.352 87.875  60.082  1.00 164.82 ? 543  LYS A CD  1 
ATOM   3982 C CE  . LYS A 1 584  ? 156.898 87.967  61.494  1.00 164.82 ? 543  LYS A CE  1 
ATOM   3983 N NZ  . LYS A 1 584  ? 157.260 86.631  62.040  1.00 164.82 ? 543  LYS A NZ  1 
ATOM   3984 N N   . LEU A 1 585  ? 152.974 88.001  59.778  1.00 163.66 ? 544  LEU A N   1 
ATOM   3985 C CA  . LEU A 1 585  ? 152.276 86.898  60.432  1.00 163.66 ? 544  LEU A CA  1 
ATOM   3986 C C   . LEU A 1 585  ? 150.984 86.558  59.699  1.00 163.66 ? 544  LEU A C   1 
ATOM   3987 O O   . LEU A 1 585  ? 150.648 85.382  59.528  1.00 163.66 ? 544  LEU A O   1 
ATOM   3988 C CB  . LEU A 1 585  ? 151.996 87.246  61.892  1.00 163.66 ? 544  LEU A CB  1 
ATOM   3989 C CG  . LEU A 1 585  ? 153.225 87.304  62.802  1.00 163.66 ? 544  LEU A CG  1 
ATOM   3990 C CD1 . LEU A 1 585  ? 152.833 87.747  64.197  1.00 163.66 ? 544  LEU A CD1 1 
ATOM   3991 C CD2 . LEU A 1 585  ? 153.935 85.959  62.842  1.00 163.66 ? 544  LEU A CD2 1 
ATOM   3992 N N   . VAL A 1 586  ? 150.252 87.578  59.250  1.00 161.55 ? 545  VAL A N   1 
ATOM   3993 C CA  . VAL A 1 586  ? 149.046 87.340  58.460  1.00 161.55 ? 545  VAL A CA  1 
ATOM   3994 C C   . VAL A 1 586  ? 149.397 86.658  57.144  1.00 161.55 ? 545  VAL A C   1 
ATOM   3995 O O   . VAL A 1 586  ? 148.682 85.760  56.680  1.00 161.55 ? 545  VAL A O   1 
ATOM   3996 C CB  . VAL A 1 586  ? 148.291 88.664  58.234  1.00 161.55 ? 545  VAL A CB  1 
ATOM   3997 C CG1 . VAL A 1 586  ? 147.245 88.507  57.150  1.00 161.55 ? 545  VAL A CG1 1 
ATOM   3998 C CG2 . VAL A 1 586  ? 147.644 89.128  59.528  1.00 161.55 ? 545  VAL A CG2 1 
ATOM   3999 N N   . GLN A 1 587  ? 150.499 87.076  56.517  1.00 162.46 ? 546  GLN A N   1 
ATOM   4000 C CA  . GLN A 1 587  ? 150.917 86.462  55.260  1.00 162.46 ? 546  GLN A CA  1 
ATOM   4001 C C   . GLN A 1 587  ? 151.247 84.988  55.447  1.00 162.46 ? 546  GLN A C   1 
ATOM   4002 O O   . GLN A 1 587  ? 150.833 84.145  54.643  1.00 162.46 ? 546  GLN A O   1 
ATOM   4003 C CB  . GLN A 1 587  ? 152.119 87.207  54.682  1.00 162.46 ? 546  GLN A CB  1 
ATOM   4004 C CG  . GLN A 1 587  ? 151.793 88.581  54.130  1.00 162.46 ? 546  GLN A CG  1 
ATOM   4005 C CD  . GLN A 1 587  ? 152.990 89.247  53.487  1.00 162.46 ? 546  GLN A CD  1 
ATOM   4006 O OE1 . GLN A 1 587  ? 154.092 88.699  53.483  1.00 162.46 ? 546  GLN A OE1 1 
ATOM   4007 N NE2 . GLN A 1 587  ? 152.781 90.438  52.939  1.00 162.46 ? 546  GLN A NE2 1 
ATOM   4008 N N   . GLU A 1 588  ? 151.987 84.651  56.504  1.00 160.08 ? 547  GLU A N   1 
ATOM   4009 C CA  . GLU A 1 588  ? 152.301 83.246  56.733  1.00 160.08 ? 547  GLU A CA  1 
ATOM   4010 C C   . GLU A 1 588  ? 151.062 82.457  57.139  1.00 160.08 ? 547  GLU A C   1 
ATOM   4011 O O   . GLU A 1 588  ? 150.944 81.276  56.793  1.00 160.08 ? 547  GLU A O   1 
ATOM   4012 C CB  . GLU A 1 588  ? 153.414 83.107  57.776  1.00 160.08 ? 547  GLU A CB  1 
ATOM   4013 C CG  . GLU A 1 588  ? 153.040 83.495  59.191  1.00 160.08 ? 547  GLU A CG  1 
ATOM   4014 C CD  . GLU A 1 588  ? 154.244 83.902  60.017  1.00 160.08 ? 547  GLU A CD  1 
ATOM   4015 O OE1 . GLU A 1 588  ? 154.814 84.980  59.747  1.00 160.08 ? 547  GLU A OE1 1 
ATOM   4016 O OE2 . GLU A 1 588  ? 154.622 83.145  60.937  1.00 160.08 ? 547  GLU A OE2 1 
ATOM   4017 N N   . ALA A 1 589  ? 150.122 83.091  57.848  1.00 157.47 ? 548  ALA A N   1 
ATOM   4018 C CA  . ALA A 1 589  ? 148.875 82.419  58.197  1.00 157.47 ? 548  ALA A CA  1 
ATOM   4019 C C   . ALA A 1 589  ? 148.049 82.100  56.959  1.00 157.47 ? 548  ALA A C   1 
ATOM   4020 O O   . ALA A 1 589  ? 147.456 81.020  56.860  1.00 157.47 ? 548  ALA A O   1 
ATOM   4021 C CB  . ALA A 1 589  ? 148.069 83.280  59.169  1.00 157.47 ? 548  ALA A CB  1 
ATOM   4022 N N   . LEU A 1 590  ? 147.987 83.030  56.006  1.00 156.84 ? 549  LEU A N   1 
ATOM   4023 C CA  . LEU A 1 590  ? 147.237 82.762  54.784  1.00 156.84 ? 549  LEU A CA  1 
ATOM   4024 C C   . LEU A 1 590  ? 147.983 81.794  53.875  1.00 156.84 ? 549  LEU A C   1 
ATOM   4025 O O   . LEU A 1 590  ? 147.353 81.063  53.103  1.00 156.84 ? 549  LEU A O   1 
ATOM   4026 C CB  . LEU A 1 590  ? 146.917 84.073  54.057  1.00 156.84 ? 549  LEU A CB  1 
ATOM   4027 C CG  . LEU A 1 590  ? 148.023 84.999  53.539  1.00 156.84 ? 549  LEU A CG  1 
ATOM   4028 C CD1 . LEU A 1 590  ? 148.555 84.569  52.175  1.00 156.84 ? 549  LEU A CD1 1 
ATOM   4029 C CD2 . LEU A 1 590  ? 147.535 86.437  53.492  1.00 156.84 ? 549  LEU A CD2 1 
ATOM   4030 N N   . ASP A 1 591  ? 149.315 81.776  53.948  1.00 156.24 ? 550  ASP A N   1 
ATOM   4031 C CA  . ASP A 1 591  ? 150.081 80.815  53.163  1.00 156.24 ? 550  ASP A CA  1 
ATOM   4032 C C   . ASP A 1 591  ? 149.873 79.396  53.678  1.00 156.24 ? 550  ASP A C   1 
ATOM   4033 O O   . ASP A 1 591  ? 149.666 78.465  52.891  1.00 156.24 ? 550  ASP A O   1 
ATOM   4034 C CB  . ASP A 1 591  ? 151.564 81.185  53.184  1.00 156.24 ? 550  ASP A CB  1 
ATOM   4035 C CG  . ASP A 1 591  ? 151.902 82.290  52.204  1.00 156.24 ? 550  ASP A CG  1 
ATOM   4036 O OD1 . ASP A 1 591  ? 151.365 82.271  51.077  1.00 156.24 ? 550  ASP A OD1 1 
ATOM   4037 O OD2 . ASP A 1 591  ? 152.704 83.179  52.563  1.00 156.24 ? 550  ASP A OD2 1 
ATOM   4038 N N   . ARG A 1 592  ? 149.929 79.209  55.000  1.00 155.95 ? 551  ARG A N   1 
ATOM   4039 C CA  . ARG A 1 592  ? 149.738 77.870  55.548  1.00 155.95 ? 551  ARG A CA  1 
ATOM   4040 C C   . ARG A 1 592  ? 148.305 77.393  55.351  1.00 155.95 ? 551  ARG A C   1 
ATOM   4041 O O   . ARG A 1 592  ? 148.068 76.200  55.133  1.00 155.95 ? 551  ARG A O   1 
ATOM   4042 C CB  . ARG A 1 592  ? 150.128 77.831  57.026  1.00 155.95 ? 551  ARG A CB  1 
ATOM   4043 C CG  . ARG A 1 592  ? 149.384 78.808  57.915  1.00 155.95 ? 551  ARG A CG  1 
ATOM   4044 C CD  . ARG A 1 592  ? 150.185 79.143  59.163  1.00 155.95 ? 551  ARG A CD  1 
ATOM   4045 N NE  . ARG A 1 592  ? 151.448 79.800  58.850  1.00 155.95 ? 551  ARG A NE  1 
ATOM   4046 C CZ  . ARG A 1 592  ? 152.633 79.211  58.918  1.00 155.95 ? 551  ARG A CZ  1 
ATOM   4047 N NH1 . ARG A 1 592  ? 152.756 77.944  59.281  1.00 155.95 ? 551  ARG A NH1 1 
ATOM   4048 N NH2 . ARG A 1 592  ? 153.724 79.909  58.616  1.00 155.95 ? 551  ARG A NH2 1 
ATOM   4049 N N   . PHE A 1 593  ? 147.333 78.302  55.442  1.00 149.90 ? 552  PHE A N   1 
ATOM   4050 C CA  . PHE A 1 593  ? 145.934 77.972  55.172  1.00 149.90 ? 552  PHE A CA  1 
ATOM   4051 C C   . PHE A 1 593  ? 145.610 78.463  53.765  1.00 149.90 ? 552  PHE A C   1 
ATOM   4052 O O   . PHE A 1 593  ? 144.937 79.476  53.569  1.00 149.90 ? 552  PHE A O   1 
ATOM   4053 C CB  . PHE A 1 593  ? 145.012 78.600  56.213  1.00 149.90 ? 552  PHE A CB  1 
ATOM   4054 C CG  . PHE A 1 593  ? 145.460 78.391  57.627  1.00 149.90 ? 552  PHE A CG  1 
ATOM   4055 C CD1 . PHE A 1 593  ? 145.918 77.157  58.052  1.00 149.90 ? 552  PHE A CD1 1 
ATOM   4056 C CD2 . PHE A 1 593  ? 145.414 79.433  58.536  1.00 149.90 ? 552  PHE A CD2 1 
ATOM   4057 C CE1 . PHE A 1 593  ? 146.335 76.971  59.355  1.00 149.90 ? 552  PHE A CE1 1 
ATOM   4058 C CE2 . PHE A 1 593  ? 145.824 79.253  59.841  1.00 149.90 ? 552  PHE A CE2 1 
ATOM   4059 C CZ  . PHE A 1 593  ? 146.284 78.020  60.250  1.00 149.90 ? 552  PHE A CZ  1 
ATOM   4060 N N   . MET A 1 594  ? 146.101 77.725  52.767  1.00 153.62 ? 553  MET A N   1 
ATOM   4061 C CA  . MET A 1 594  ? 145.903 78.157  51.389  1.00 153.62 ? 553  MET A CA  1 
ATOM   4062 C C   . MET A 1 594  ? 144.434 78.172  50.991  1.00 153.62 ? 553  MET A C   1 
ATOM   4063 O O   . MET A 1 594  ? 144.083 78.844  50.014  1.00 153.62 ? 553  MET A O   1 
ATOM   4064 C CB  . MET A 1 594  ? 146.699 77.283  50.413  1.00 153.62 ? 553  MET A CB  1 
ATOM   4065 C CG  . MET A 1 594  ? 146.182 75.865  50.230  1.00 153.62 ? 553  MET A CG  1 
ATOM   4066 S SD  . MET A 1 594  ? 146.029 74.950  51.771  1.00 153.62 ? 553  MET A SD  1 
ATOM   4067 C CE  . MET A 1 594  ? 147.740 74.913  52.301  1.00 153.62 ? 553  MET A CE  1 
ATOM   4068 N N   . ILE A 1 595  ? 143.565 77.474  51.728  1.00 146.62 ? 554  ILE A N   1 
ATOM   4069 C CA  . ILE A 1 595  ? 142.137 77.554  51.434  1.00 146.62 ? 554  ILE A CA  1 
ATOM   4070 C C   . ILE A 1 595  ? 141.640 78.976  51.654  1.00 146.62 ? 554  ILE A C   1 
ATOM   4071 O O   . ILE A 1 595  ? 140.656 79.402  51.039  1.00 146.62 ? 554  ILE A O   1 
ATOM   4072 C CB  . ILE A 1 595  ? 141.335 76.541  52.281  1.00 146.62 ? 554  ILE A CB  1 
ATOM   4073 C CG1 . ILE A 1 595  ? 141.793 75.104  52.027  1.00 146.62 ? 554  ILE A CG1 1 
ATOM   4074 C CG2 . ILE A 1 595  ? 139.855 76.615  51.953  1.00 146.62 ? 554  ILE A CG2 1 
ATOM   4075 C CD1 . ILE A 1 595  ? 142.840 74.610  52.995  1.00 146.62 ? 554  ILE A CD1 1 
ATOM   4076 N N   . GLY A 1 596  ? 142.311 79.733  52.518  1.00 145.97 ? 555  GLY A N   1 
ATOM   4077 C CA  . GLY A 1 596  ? 141.908 81.094  52.818  1.00 145.97 ? 555  GLY A CA  1 
ATOM   4078 C C   . GLY A 1 596  ? 141.952 82.031  51.630  1.00 145.97 ? 555  GLY A C   1 
ATOM   4079 O O   . GLY A 1 596  ? 142.990 82.175  50.978  1.00 145.97 ? 555  GLY A O   1 
ATOM   4080 N N   . ARG A 1 597  ? 140.826 82.678  51.344  1.00 150.40 ? 556  ARG A N   1 
ATOM   4081 C CA  . ARG A 1 597  ? 140.708 83.600  50.222  1.00 150.40 ? 556  ARG A CA  1 
ATOM   4082 C C   . ARG A 1 597  ? 139.960 84.835  50.705  1.00 150.40 ? 556  ARG A C   1 
ATOM   4083 O O   . ARG A 1 597  ? 139.773 85.042  51.907  1.00 150.40 ? 556  ARG A O   1 
ATOM   4084 C CB  . ARG A 1 597  ? 139.990 82.948  49.032  1.00 150.40 ? 556  ARG A CB  1 
ATOM   4085 C CG  . ARG A 1 597  ? 140.297 81.478  48.824  1.00 150.40 ? 556  ARG A CG  1 
ATOM   4086 C CD  . ARG A 1 597  ? 139.120 80.755  48.196  1.00 150.40 ? 556  ARG A CD  1 
ATOM   4087 N NE  . ARG A 1 597  ? 139.374 79.332  48.006  1.00 150.40 ? 556  ARG A NE  1 
ATOM   4088 C CZ  . ARG A 1 597  ? 138.951 78.380  48.826  1.00 150.40 ? 556  ARG A CZ  1 
ATOM   4089 N NH1 . ARG A 1 597  ? 138.238 78.663  49.903  1.00 150.40 ? 556  ARG A NH1 1 
ATOM   4090 N NH2 . ARG A 1 597  ? 139.250 77.112  48.558  1.00 150.40 ? 556  ARG A NH2 1 
ATOM   4091 N N   . THR A 1 598  ? 139.541 85.666  49.749  1.00 144.47 ? 557  THR A N   1 
ATOM   4092 C CA  . THR A 1 598  ? 138.664 86.810  49.999  1.00 144.47 ? 557  THR A CA  1 
ATOM   4093 C C   . THR A 1 598  ? 139.288 87.761  51.025  1.00 144.47 ? 557  THR A C   1 
ATOM   4094 O O   . THR A 1 598  ? 138.805 87.940  52.143  1.00 144.47 ? 557  THR A O   1 
ATOM   4095 C CB  . THR A 1 598  ? 137.274 86.343  50.445  1.00 144.47 ? 557  THR A CB  1 
ATOM   4096 O OG1 . THR A 1 598  ? 136.866 85.227  49.643  1.00 144.47 ? 557  THR A OG1 1 
ATOM   4097 C CG2 . THR A 1 598  ? 136.258 87.464  50.283  1.00 144.47 ? 557  THR A CG2 1 
ATOM   4098 N N   . THR A 1 599  ? 140.403 88.351  50.611  1.00 147.08 ? 558  THR A N   1 
ATOM   4099 C CA  . THR A 1 599  ? 141.087 89.358  51.407  1.00 147.08 ? 558  THR A CA  1 
ATOM   4100 C C   . THR A 1 599  ? 140.593 90.737  50.992  1.00 147.08 ? 558  THR A C   1 
ATOM   4101 O O   . THR A 1 599  ? 140.742 91.132  49.831  1.00 147.08 ? 558  THR A O   1 
ATOM   4102 C CB  . THR A 1 599  ? 142.600 89.255  51.228  1.00 147.08 ? 558  THR A CB  1 
ATOM   4103 O OG1 . THR A 1 599  ? 143.067 88.022  51.785  1.00 147.08 ? 558  THR A OG1 1 
ATOM   4104 C CG2 . THR A 1 599  ? 143.297 90.418  51.914  1.00 147.08 ? 558  THR A CG2 1 
ATOM   4105 N N   . LEU A 1 600  ? 140.000 91.467  51.937  1.00 152.02 ? 559  LEU A N   1 
ATOM   4106 C CA  . LEU A 1 600  ? 139.543 92.833  51.683  1.00 152.02 ? 559  LEU A CA  1 
ATOM   4107 C C   . LEU A 1 600  ? 140.711 93.809  51.847  1.00 152.02 ? 559  LEU A C   1 
ATOM   4108 O O   . LEU A 1 600  ? 140.723 94.695  52.702  1.00 152.02 ? 559  LEU A O   1 
ATOM   4109 C CB  . LEU A 1 600  ? 138.384 93.184  52.605  1.00 152.02 ? 559  LEU A CB  1 
ATOM   4110 C CG  . LEU A 1 600  ? 136.988 93.104  51.987  1.00 152.02 ? 559  LEU A CG  1 
ATOM   4111 C CD1 . LEU A 1 600  ? 136.740 91.729  51.389  1.00 152.02 ? 559  LEU A CD1 1 
ATOM   4112 C CD2 . LEU A 1 600  ? 135.930 93.440  53.024  1.00 152.02 ? 559  LEU A CD2 1 
ATOM   4113 N N   . ILE A 1 601  ? 141.713 93.619  50.987  1.00 164.96 ? 560  ILE A N   1 
ATOM   4114 C CA  . ILE A 1 601  ? 142.955 94.376  51.081  1.00 164.96 ? 560  ILE A CA  1 
ATOM   4115 C C   . ILE A 1 601  ? 142.746 95.839  50.706  1.00 164.96 ? 560  ILE A C   1 
ATOM   4116 O O   . ILE A 1 601  ? 143.425 96.723  51.244  1.00 164.96 ? 560  ILE A O   1 
ATOM   4117 C CB  . ILE A 1 601  ? 144.029 93.707  50.205  1.00 164.96 ? 560  ILE A CB  1 
ATOM   4118 C CG1 . ILE A 1 601  ? 145.374 94.413  50.356  1.00 164.96 ? 560  ILE A CG1 1 
ATOM   4119 C CG2 . ILE A 1 601  ? 143.593 93.666  48.747  1.00 164.96 ? 560  ILE A CG2 1 
ATOM   4120 C CD1 . ILE A 1 601  ? 146.499 93.650  49.734  1.00 164.96 ? 560  ILE A CD1 1 
ATOM   4121 N N   . ILE A 1 602  ? 141.801 96.113  49.800  1.00 168.09 ? 561  ILE A N   1 
ATOM   4122 C CA  . ILE A 1 602  ? 141.536 97.425  49.209  1.00 168.09 ? 561  ILE A CA  1 
ATOM   4123 C C   . ILE A 1 602  ? 142.842 98.184  48.961  1.00 168.09 ? 561  ILE A C   1 
ATOM   4124 O O   . ILE A 1 602  ? 143.053 99.292  49.468  1.00 168.09 ? 561  ILE A O   1 
ATOM   4125 C CB  . ILE A 1 602  ? 140.515 98.231  50.054  1.00 168.09 ? 561  ILE A CB  1 
ATOM   4126 C CG1 . ILE A 1 602  ? 140.049 99.488  49.306  1.00 168.09 ? 561  ILE A CG1 1 
ATOM   4127 C CG2 . ILE A 1 602  ? 141.009 98.549  51.475  1.00 168.09 ? 561  ILE A CG2 1 
ATOM   4128 C CD1 . ILE A 1 602  ? 138.992 100.279 50.041  1.00 168.09 ? 561  ILE A CD1 1 
ATOM   4129 N N   . ALA A 1 603  ? 143.729 97.574  48.170  1.00 172.59 ? 562  ALA A N   1 
ATOM   4130 C CA  . ALA A 1 603  ? 144.954 98.207  47.675  1.00 172.59 ? 562  ALA A CA  1 
ATOM   4131 C C   . ALA A 1 603  ? 145.835 98.692  48.832  1.00 172.59 ? 562  ALA A C   1 
ATOM   4132 O O   . ALA A 1 603  ? 146.065 99.886  49.028  1.00 172.59 ? 562  ALA A O   1 
ATOM   4133 C CB  . ALA A 1 603  ? 144.621 99.353  46.714  1.00 172.59 ? 562  ALA A CB  1 
ATOM   4134 N N   . HIS A 1 604  ? 146.323 97.720  49.603  1.00 168.47 ? 563  HIS A N   1 
ATOM   4135 C CA  . HIS A 1 604  ? 147.178 98.015  50.745  1.00 168.47 ? 563  HIS A CA  1 
ATOM   4136 C C   . HIS A 1 604  ? 148.470 97.214  50.794  1.00 168.47 ? 563  HIS A C   1 
ATOM   4137 O O   . HIS A 1 604  ? 149.379 97.605  51.538  1.00 168.47 ? 563  HIS A O   1 
ATOM   4138 C CB  . HIS A 1 604  ? 146.413 97.793  52.057  1.00 168.47 ? 563  HIS A CB  1 
ATOM   4139 C CG  . HIS A 1 604  ? 145.558 98.954  52.452  1.00 168.47 ? 563  HIS A CG  1 
ATOM   4140 N ND1 . HIS A 1 604  ? 144.390 99.274  51.793  1.00 168.47 ? 563  HIS A ND1 1 
ATOM   4141 C CD2 . HIS A 1 604  ? 145.700 99.873  53.435  1.00 168.47 ? 563  HIS A CD2 1 
ATOM   4142 C CE1 . HIS A 1 604  ? 143.852 100.343 52.351  1.00 168.47 ? 563  HIS A CE1 1 
ATOM   4143 N NE2 . HIS A 1 604  ? 144.626 100.725 53.351  1.00 168.47 ? 563  HIS A NE2 1 
ATOM   4144 N N   . ARG A 1 605  ? 148.594 96.121  50.044  1.00 173.11 ? 564  ARG A N   1 
ATOM   4145 C CA  . ARG A 1 605  ? 149.817 95.321  50.066  1.00 173.11 ? 564  ARG A CA  1 
ATOM   4146 C C   . ARG A 1 605  ? 149.956 94.650  48.703  1.00 173.11 ? 564  ARG A C   1 
ATOM   4147 O O   . ARG A 1 605  ? 149.344 93.608  48.456  1.00 173.11 ? 564  ARG A O   1 
ATOM   4148 C CB  . ARG A 1 605  ? 149.781 94.304  51.199  1.00 173.11 ? 564  ARG A CB  1 
ATOM   4149 C CG  . ARG A 1 605  ? 150.997 93.395  51.281  1.00 173.11 ? 564  ARG A CG  1 
ATOM   4150 C CD  . ARG A 1 605  ? 152.237 94.148  51.738  1.00 173.11 ? 564  ARG A CD  1 
ATOM   4151 N NE  . ARG A 1 605  ? 152.925 94.796  50.627  1.00 173.11 ? 564  ARG A NE  1 
ATOM   4152 C CZ  . ARG A 1 605  ? 153.936 95.642  50.763  1.00 173.11 ? 564  ARG A CZ  1 
ATOM   4153 N NH1 . ARG A 1 605  ? 154.403 95.976  51.954  1.00 173.11 ? 564  ARG A NH1 1 
ATOM   4154 N NH2 . ARG A 1 605  ? 154.492 96.167  49.674  1.00 173.11 ? 564  ARG A NH2 1 
ATOM   4155 N N   . LEU A 1 606  ? 150.772 95.248  47.831  1.00 174.52 ? 565  LEU A N   1 
ATOM   4156 C CA  . LEU A 1 606  ? 150.929 94.719  46.480  1.00 174.52 ? 565  LEU A CA  1 
ATOM   4157 C C   . LEU A 1 606  ? 151.548 93.327  46.486  1.00 174.52 ? 565  LEU A C   1 
ATOM   4158 O O   . LEU A 1 606  ? 151.310 92.541  45.561  1.00 174.52 ? 565  LEU A O   1 
ATOM   4159 C CB  . LEU A 1 606  ? 151.772 95.680  45.640  1.00 174.52 ? 565  LEU A CB  1 
ATOM   4160 C CG  . LEU A 1 606  ? 151.808 95.475  44.122  1.00 174.52 ? 565  LEU A CG  1 
ATOM   4161 C CD1 . LEU A 1 606  ? 151.795 96.817  43.411  1.00 174.52 ? 565  LEU A CD1 1 
ATOM   4162 C CD2 . LEU A 1 606  ? 153.030 94.670  43.706  1.00 174.52 ? 565  LEU A CD2 1 
ATOM   4163 N N   . SER A 1 607  ? 152.338 92.999  47.511  1.00 173.77 ? 566  SER A N   1 
ATOM   4164 C CA  . SER A 1 607  ? 152.961 91.680  47.567  1.00 173.77 ? 566  SER A CA  1 
ATOM   4165 C C   . SER A 1 607  ? 151.909 90.586  47.698  1.00 173.77 ? 566  SER A C   1 
ATOM   4166 O O   . SER A 1 607  ? 151.927 89.600  46.953  1.00 173.77 ? 566  SER A O   1 
ATOM   4167 C CB  . SER A 1 607  ? 153.953 91.608  48.727  1.00 173.77 ? 566  SER A CB  1 
ATOM   4168 O OG  . SER A 1 607  ? 153.285 91.670  49.972  1.00 173.77 ? 566  SER A OG  1 
ATOM   4169 N N   . THR A 1 608  ? 150.975 90.746  48.639  1.00 173.49 ? 567  THR A N   1 
ATOM   4170 C CA  . THR A 1 608  ? 149.897 89.773  48.773  1.00 173.49 ? 567  THR A CA  1 
ATOM   4171 C C   . THR A 1 608  ? 148.990 89.776  47.552  1.00 173.49 ? 567  THR A C   1 
ATOM   4172 O O   . THR A 1 608  ? 148.400 88.742  47.217  1.00 173.49 ? 567  THR A O   1 
ATOM   4173 C CB  . THR A 1 608  ? 149.082 90.050  50.035  1.00 173.49 ? 567  THR A CB  1 
ATOM   4174 O OG1 . THR A 1 608  ? 148.749 91.441  50.092  1.00 173.49 ? 567  THR A OG1 1 
ATOM   4175 C CG2 . THR A 1 608  ? 149.877 89.676  51.271  1.00 173.49 ? 567  THR A CG2 1 
ATOM   4176 N N   . ILE A 1 609  ? 148.859 90.923  46.882  1.00 174.61 ? 568  ILE A N   1 
ATOM   4177 C CA  . ILE A 1 609  ? 148.114 90.967  45.629  1.00 174.61 ? 568  ILE A CA  1 
ATOM   4178 C C   . ILE A 1 609  ? 148.773 90.061  44.597  1.00 174.61 ? 568  ILE A C   1 
ATOM   4179 O O   . ILE A 1 609  ? 148.099 89.291  43.902  1.00 174.61 ? 568  ILE A O   1 
ATOM   4180 C CB  . ILE A 1 609  ? 148.001 92.417  45.125  1.00 174.61 ? 568  ILE A CB  1 
ATOM   4181 C CG1 . ILE A 1 609  ? 147.190 93.261  46.110  1.00 174.61 ? 568  ILE A CG1 1 
ATOM   4182 C CG2 . ILE A 1 609  ? 147.366 92.458  43.748  1.00 174.61 ? 568  ILE A CG2 1 
ATOM   4183 C CD1 . ILE A 1 609  ? 147.247 94.746  45.832  1.00 174.61 ? 568  ILE A CD1 1 
ATOM   4184 N N   . ARG A 1 610  ? 150.101 90.130  44.492  1.00 174.35 ? 569  ARG A N   1 
ATOM   4185 C CA  . ARG A 1 610  ? 150.817 89.231  43.592  1.00 174.35 ? 569  ARG A CA  1 
ATOM   4186 C C   . ARG A 1 610  ? 150.720 87.785  44.066  1.00 174.35 ? 569  ARG A C   1 
ATOM   4187 O O   . ARG A 1 610  ? 150.779 86.853  43.256  1.00 174.35 ? 569  ARG A O   1 
ATOM   4188 C CB  . ARG A 1 610  ? 152.278 89.662  43.470  1.00 174.35 ? 569  ARG A CB  1 
ATOM   4189 C CG  . ARG A 1 610  ? 152.481 91.067  42.913  1.00 174.35 ? 569  ARG A CG  1 
ATOM   4190 C CD  . ARG A 1 610  ? 152.257 91.123  41.404  1.00 174.35 ? 569  ARG A CD  1 
ATOM   4191 N NE  . ARG A 1 610  ? 150.849 91.265  41.050  1.00 174.35 ? 569  ARG A NE  1 
ATOM   4192 C CZ  . ARG A 1 610  ? 150.180 92.410  41.075  1.00 174.35 ? 569  ARG A CZ  1 
ATOM   4193 N NH1 . ARG A 1 610  ? 150.763 93.544  41.429  1.00 174.35 ? 569  ARG A NH1 1 
ATOM   4194 N NH2 . ARG A 1 610  ? 148.896 92.419  40.728  1.00 174.35 ? 569  ARG A NH2 1 
ATOM   4195 N N   . LYS A 1 611  ? 150.582 87.580  45.378  1.00 171.34 ? 570  LYS A N   1 
ATOM   4196 C CA  . LYS A 1 611  ? 150.418 86.227  45.902  1.00 171.34 ? 570  LYS A CA  1 
ATOM   4197 C C   . LYS A 1 611  ? 149.113 85.602  45.423  1.00 171.34 ? 570  LYS A C   1 
ATOM   4198 O O   . LYS A 1 611  ? 149.074 84.416  45.075  1.00 171.34 ? 570  LYS A O   1 
ATOM   4199 C CB  . LYS A 1 611  ? 150.468 86.239  47.430  1.00 171.34 ? 570  LYS A CB  1 
ATOM   4200 C CG  . LYS A 1 611  ? 151.801 86.662  48.013  1.00 171.34 ? 570  LYS A CG  1 
ATOM   4201 C CD  . LYS A 1 611  ? 152.891 85.651  47.707  1.00 171.34 ? 570  LYS A CD  1 
ATOM   4202 C CE  . LYS A 1 611  ? 154.098 85.867  48.603  1.00 171.34 ? 570  LYS A CE  1 
ATOM   4203 N NZ  . LYS A 1 611  ? 154.669 87.232  48.442  1.00 171.34 ? 570  LYS A NZ  1 
ATOM   4204 N N   . ALA A 1 612  ? 148.037 86.382  45.401  1.00 168.06 ? 571  ALA A N   1 
ATOM   4205 C CA  . ALA A 1 612  ? 146.738 85.854  45.012  1.00 168.06 ? 571  ALA A CA  1 
ATOM   4206 C C   . ALA A 1 612  ? 146.718 85.525  43.527  1.00 168.06 ? 571  ALA A C   1 
ATOM   4207 O O   . ALA A 1 612  ? 147.106 86.350  42.693  1.00 168.06 ? 571  ALA A O   1 
ATOM   4208 C CB  . ALA A 1 612  ? 145.636 86.858  45.347  1.00 168.06 ? 571  ALA A CB  1 
ATOM   4209 N N   . ASP A 1 613  ? 146.265 84.314  43.196  1.00 165.31 ? 572  ASP A N   1 
ATOM   4210 C CA  . ASP A 1 613  ? 146.143 83.934  41.792  1.00 165.31 ? 572  ASP A CA  1 
ATOM   4211 C C   . ASP A 1 613  ? 145.107 84.793  41.080  1.00 165.31 ? 572  ASP A C   1 
ATOM   4212 O O   . ASP A 1 613  ? 145.311 85.202  39.930  1.00 165.31 ? 572  ASP A O   1 
ATOM   4213 C CB  . ASP A 1 613  ? 145.792 82.450  41.673  1.00 165.31 ? 572  ASP A CB  1 
ATOM   4214 C CG  . ASP A 1 613  ? 144.437 82.117  42.274  1.00 165.31 ? 572  ASP A CG  1 
ATOM   4215 O OD1 . ASP A 1 613  ? 143.920 82.927  43.071  1.00 165.31 ? 572  ASP A OD1 1 
ATOM   4216 O OD2 . ASP A 1 613  ? 143.890 81.042  41.949  1.00 165.31 ? 572  ASP A OD2 1 
ATOM   4217 N N   . LEU A 1 614  ? 143.990 85.078  41.745  1.00 163.98 ? 573  LEU A N   1 
ATOM   4218 C CA  . LEU A 1 614  ? 142.936 85.921  41.203  1.00 163.98 ? 573  LEU A CA  1 
ATOM   4219 C C   . LEU A 1 614  ? 142.782 87.142  42.094  1.00 163.98 ? 573  LEU A C   1 
ATOM   4220 O O   . LEU A 1 614  ? 142.666 87.012  43.316  1.00 163.98 ? 573  LEU A O   1 
ATOM   4221 C CB  . LEU A 1 614  ? 141.612 85.158  41.108  1.00 163.98 ? 573  LEU A CB  1 
ATOM   4222 C CG  . LEU A 1 614  ? 141.673 83.735  40.548  1.00 163.98 ? 573  LEU A CG  1 
ATOM   4223 C CD1 . LEU A 1 614  ? 140.279 83.134  40.472  1.00 163.98 ? 573  LEU A CD1 1 
ATOM   4224 C CD2 . LEU A 1 614  ? 142.342 83.713  39.184  1.00 163.98 ? 573  LEU A CD2 1 
ATOM   4225 N N   . VAL A 1 615  ? 142.792 88.324  41.484  1.00 163.77 ? 574  VAL A N   1 
ATOM   4226 C CA  . VAL A 1 615  ? 142.690 89.573  42.228  1.00 163.77 ? 574  VAL A CA  1 
ATOM   4227 C C   . VAL A 1 615  ? 141.465 90.294  41.667  1.00 163.77 ? 574  VAL A C   1 
ATOM   4228 O O   . VAL A 1 615  ? 141.450 91.518  41.501  1.00 163.77 ? 574  VAL A O   1 
ATOM   4229 C CB  . VAL A 1 615  ? 144.003 90.381  42.127  1.00 163.77 ? 574  VAL A CB  1 
ATOM   4230 C CG1 . VAL A 1 615  ? 143.918 91.744  42.824  1.00 163.77 ? 574  VAL A CG1 1 
ATOM   4231 C CG2 . VAL A 1 615  ? 145.154 89.572  42.695  1.00 163.77 ? 574  VAL A CG2 1 
ATOM   4232 N N   . ALA A 1 616  ? 140.441 89.515  41.319  1.00 165.30 ? 575  ALA A N   1 
ATOM   4233 C CA  . ALA A 1 616  ? 139.223 90.067  40.740  1.00 165.30 ? 575  ALA A CA  1 
ATOM   4234 C C   . ALA A 1 616  ? 138.663 91.183  41.613  1.00 165.30 ? 575  ALA A C   1 
ATOM   4235 O O   . ALA A 1 616  ? 138.538 91.034  42.832  1.00 165.30 ? 575  ALA A O   1 
ATOM   4236 C CB  . ALA A 1 616  ? 138.180 88.962  40.562  1.00 165.30 ? 575  ALA A CB  1 
ATOM   4237 N N   . VAL A 1 617  ? 138.331 92.299  40.980  1.00 167.59 ? 576  VAL A N   1 
ATOM   4238 C CA  . VAL A 1 617  ? 137.967 93.509  41.685  1.00 167.59 ? 576  VAL A CA  1 
ATOM   4239 C C   . VAL A 1 617  ? 136.449 93.640  41.719  1.00 167.59 ? 576  VAL A C   1 
ATOM   4240 O O   . VAL A 1 617  ? 135.727 92.973  40.983  1.00 167.59 ? 576  VAL A O   1 
ATOM   4241 C CB  . VAL A 1 617  ? 138.622 94.756  41.051  1.00 167.59 ? 576  VAL A CB  1 
ATOM   4242 C CG1 . VAL A 1 617  ? 140.136 94.652  41.129  1.00 167.59 ? 576  VAL A CG1 1 
ATOM   4243 C CG2 . VAL A 1 617  ? 138.171 94.916  39.616  1.00 167.59 ? 576  VAL A CG2 1 
ATOM   4244 N N   . LEU A 1 618  ? 135.958 94.521  42.588  1.00 170.18 ? 577  LEU A N   1 
ATOM   4245 C CA  . LEU A 1 618  ? 134.525 94.693  42.781  1.00 170.18 ? 577  LEU A CA  1 
ATOM   4246 C C   . LEU A 1 618  ? 134.164 96.154  42.528  1.00 170.18 ? 577  LEU A C   1 
ATOM   4247 O O   . LEU A 1 618  ? 133.496 96.798  43.344  1.00 170.18 ? 577  LEU A O   1 
ATOM   4248 C CB  . LEU A 1 618  ? 134.124 94.233  44.188  1.00 170.18 ? 577  LEU A CB  1 
ATOM   4249 C CG  . LEU A 1 618  ? 132.663 94.234  44.645  1.00 170.18 ? 577  LEU A CG  1 
ATOM   4250 C CD1 . LEU A 1 618  ? 131.848 93.283  43.792  1.00 170.18 ? 577  LEU A CD1 1 
ATOM   4251 C CD2 . LEU A 1 618  ? 132.559 93.862  46.114  1.00 170.18 ? 577  LEU A CD2 1 
ATOM   4252 N N   . GLN A 1 619  ? 134.641 96.695  41.410  1.00 175.35 ? 578  GLN A N   1 
ATOM   4253 C CA  . GLN A 1 619  ? 134.373 98.086  41.073  1.00 175.35 ? 578  GLN A CA  1 
ATOM   4254 C C   . GLN A 1 619  ? 132.877 98.320  40.888  1.00 175.35 ? 578  GLN A C   1 
ATOM   4255 O O   . GLN A 1 619  ? 132.156 97.462  40.370  1.00 175.35 ? 578  GLN A O   1 
ATOM   4256 C CB  . GLN A 1 619  ? 135.150 98.475  39.812  1.00 175.35 ? 578  GLN A CB  1 
ATOM   4257 C CG  . GLN A 1 619  ? 134.854 97.614  38.593  1.00 175.35 ? 578  GLN A CG  1 
ATOM   4258 C CD  . GLN A 1 619  ? 133.772 98.196  37.711  1.00 175.35 ? 578  GLN A CD  1 
ATOM   4259 O OE1 . GLN A 1 619  ? 133.659 99.412  37.572  1.00 175.35 ? 578  GLN A OE1 1 
ATOM   4260 N NE2 . GLN A 1 619  ? 132.967 97.327  37.110  1.00 175.35 ? 578  GLN A NE2 1 
ATOM   4261 N N   . GLN A 1 620  ? 132.419 99.499  41.327  1.00 177.53 ? 579  GLN A N   1 
ATOM   4262 C CA  . GLN A 1 620  ? 131.012 99.898  41.395  1.00 177.53 ? 579  GLN A CA  1 
ATOM   4263 C C   . GLN A 1 620  ? 130.107 98.754  41.837  1.00 177.53 ? 579  GLN A C   1 
ATOM   4264 O O   . GLN A 1 620  ? 129.016 98.566  41.289  1.00 177.53 ? 579  GLN A O   1 
ATOM   4265 C CB  . GLN A 1 620  ? 130.518 100.485 40.060  1.00 177.53 ? 579  GLN A CB  1 
ATOM   4266 C CG  . GLN A 1 620  ? 130.815 99.690  38.797  1.00 177.53 ? 579  GLN A CG  1 
ATOM   4267 C CD  . GLN A 1 620  ? 129.674 98.782  38.382  1.00 177.53 ? 579  GLN A CD  1 
ATOM   4268 O OE1 . GLN A 1 620  ? 128.503 99.101  38.587  1.00 177.53 ? 579  GLN A OE1 1 
ATOM   4269 N NE2 . GLN A 1 620  ? 130.013 97.643  37.788  1.00 177.53 ? 579  GLN A NE2 1 
ATOM   4270 N N   . GLY A 1 621  ? 130.544 97.998  42.839  1.00 174.65 ? 580  GLY A N   1 
ATOM   4271 C CA  . GLY A 1 621  ? 129.740 96.902  43.356  1.00 174.65 ? 580  GLY A CA  1 
ATOM   4272 C C   . GLY A 1 621  ? 129.471 95.806  42.349  1.00 174.65 ? 580  GLY A C   1 
ATOM   4273 O O   . GLY A 1 621  ? 128.351 95.286  42.289  1.00 174.65 ? 580  GLY A O   1 
ATOM   4274 N N   . SER A 1 622  ? 130.474 95.448  41.549  1.00 172.78 ? 581  SER A N   1 
ATOM   4275 C CA  . SER A 1 622  ? 130.342 94.369  40.581  1.00 172.78 ? 581  SER A CA  1 
ATOM   4276 C C   . SER A 1 622  ? 131.731 93.941  40.133  1.00 172.78 ? 581  SER A C   1 
ATOM   4277 O O   . SER A 1 622  ? 132.666 94.744  40.117  1.00 172.78 ? 581  SER A O   1 
ATOM   4278 C CB  . SER A 1 622  ? 129.496 94.788  39.375  1.00 172.78 ? 581  SER A CB  1 
ATOM   4279 O OG  . SER A 1 622  ? 128.116 94.804  39.700  1.00 172.78 ? 581  SER A OG  1 
ATOM   4280 N N   . VAL A 1 623  ? 131.853 92.670  39.766  1.00 170.93 ? 582  VAL A N   1 
ATOM   4281 C CA  . VAL A 1 623  ? 133.124 92.142  39.282  1.00 170.93 ? 582  VAL A CA  1 
ATOM   4282 C C   . VAL A 1 623  ? 133.294 92.518  37.816  1.00 170.93 ? 582  VAL A C   1 
ATOM   4283 O O   . VAL A 1 623  ? 132.378 92.340  37.003  1.00 170.93 ? 582  VAL A O   1 
ATOM   4284 C CB  . VAL A 1 623  ? 133.200 90.620  39.484  1.00 170.93 ? 582  VAL A CB  1 
ATOM   4285 C CG1 . VAL A 1 623  ? 133.346 90.291  40.959  1.00 170.93 ? 582  VAL A CG1 1 
ATOM   4286 C CG2 . VAL A 1 623  ? 131.971 89.941  38.909  1.00 170.93 ? 582  VAL A CG2 1 
ATOM   4287 N N   . SER A 1 624  ? 134.461 93.060  37.477  1.00 172.79 ? 583  SER A N   1 
ATOM   4288 C CA  . SER A 1 624  ? 134.765 93.468  36.113  1.00 172.79 ? 583  SER A CA  1 
ATOM   4289 C C   . SER A 1 624  ? 135.709 92.504  35.410  1.00 172.79 ? 583  SER A C   1 
ATOM   4290 O O   . SER A 1 624  ? 135.388 92.005  34.327  1.00 172.79 ? 583  SER A O   1 
ATOM   4291 C CB  . SER A 1 624  ? 135.364 94.880  36.106  1.00 172.79 ? 583  SER A CB  1 
ATOM   4292 O OG  . SER A 1 624  ? 136.553 94.931  36.871  1.00 172.79 ? 583  SER A OG  1 
ATOM   4293 N N   . GLU A 1 625  ? 136.867 92.227  36.000  1.00 174.11 ? 584  GLU A N   1 
ATOM   4294 C CA  . GLU A 1 625  ? 137.826 91.286  35.439  1.00 174.11 ? 584  GLU A CA  1 
ATOM   4295 C C   . GLU A 1 625  ? 138.163 90.222  36.472  1.00 174.11 ? 584  GLU A C   1 
ATOM   4296 O O   . GLU A 1 625  ? 138.340 90.524  37.656  1.00 174.11 ? 584  GLU A O   1 
ATOM   4297 C CB  . GLU A 1 625  ? 139.102 91.999  34.967  1.00 174.11 ? 584  GLU A CB  1 
ATOM   4298 C CG  . GLU A 1 625  ? 139.932 92.639  36.071  1.00 174.11 ? 584  GLU A CG  1 
ATOM   4299 C CD  . GLU A 1 625  ? 139.732 94.137  36.158  1.00 174.11 ? 584  GLU A CD  1 
ATOM   4300 O OE1 . GLU A 1 625  ? 138.619 94.608  35.846  1.00 174.11 ? 584  GLU A OE1 1 
ATOM   4301 O OE2 . GLU A 1 625  ? 140.689 94.845  36.535  1.00 174.11 ? 584  GLU A OE2 1 
ATOM   4302 N N   . ILE A 1 626  ? 138.230 88.974  36.019  1.00 173.90 ? 585  ILE A N   1 
ATOM   4303 C CA  . ILE A 1 626  ? 138.584 87.839  36.862  1.00 173.90 ? 585  ILE A CA  1 
ATOM   4304 C C   . ILE A 1 626  ? 139.721 87.088  36.185  1.00 173.90 ? 585  ILE A C   1 
ATOM   4305 O O   . ILE A 1 626  ? 139.631 86.761  34.996  1.00 173.90 ? 585  ILE A O   1 
ATOM   4306 C CB  . ILE A 1 626  ? 137.386 86.900  37.099  1.00 173.90 ? 585  ILE A CB  1 
ATOM   4307 C CG1 . ILE A 1 626  ? 136.228 87.658  37.755  1.00 173.90 ? 585  ILE A CG1 1 
ATOM   4308 C CG2 . ILE A 1 626  ? 137.800 85.713  37.956  1.00 173.90 ? 585  ILE A CG2 1 
ATOM   4309 C CD1 . ILE A 1 626  ? 135.093 87.980  36.808  1.00 173.90 ? 585  ILE A CD1 1 
ATOM   4310 N N   . GLY A 1 627  ? 140.784 86.816  36.936  1.00 174.37 ? 586  GLY A N   1 
ATOM   4311 C CA  . GLY A 1 627  ? 141.908 86.092  36.376  1.00 174.37 ? 586  GLY A CA  1 
ATOM   4312 C C   . GLY A 1 627  ? 143.261 86.679  36.714  1.00 174.37 ? 586  GLY A C   1 
ATOM   4313 O O   . GLY A 1 627  ? 143.646 86.742  37.886  1.00 174.37 ? 586  GLY A O   1 
ATOM   4314 N N   . THR A 1 628  ? 143.993 87.107  35.690  1.00 177.89 ? 587  THR A N   1 
ATOM   4315 C CA  . THR A 1 628  ? 145.357 87.580  35.872  1.00 177.89 ? 587  THR A CA  1 
ATOM   4316 C C   . THR A 1 628  ? 145.391 88.850  36.720  1.00 177.89 ? 587  THR A C   1 
ATOM   4317 O O   . THR A 1 628  ? 144.379 89.524  36.935  1.00 177.89 ? 587  THR A O   1 
ATOM   4318 C CB  . THR A 1 628  ? 146.021 87.841  34.519  1.00 177.89 ? 587  THR A CB  1 
ATOM   4319 O OG1 . THR A 1 628  ? 145.253 88.799  33.782  1.00 177.89 ? 587  THR A OG1 1 
ATOM   4320 C CG2 . THR A 1 628  ? 146.123 86.551  33.718  1.00 177.89 ? 587  THR A CG2 1 
ATOM   4321 N N   . HIS A 1 629  ? 146.587 89.165  37.210  1.00 176.14 ? 588  HIS A N   1 
ATOM   4322 C CA  . HIS A 1 629  ? 146.812 90.283  38.119  1.00 176.14 ? 588  HIS A CA  1 
ATOM   4323 C C   . HIS A 1 629  ? 148.073 91.037  37.729  1.00 176.14 ? 588  HIS A C   1 
ATOM   4324 O O   . HIS A 1 629  ? 148.868 91.438  38.584  1.00 176.14 ? 588  HIS A O   1 
ATOM   4325 C CB  . HIS A 1 629  ? 146.910 89.797  39.562  1.00 176.14 ? 588  HIS A CB  1 
ATOM   4326 C CG  . HIS A 1 629  ? 147.935 88.725  39.764  1.00 176.14 ? 588  HIS A CG  1 
ATOM   4327 N ND1 . HIS A 1 629  ? 149.053 88.902  40.550  1.00 176.14 ? 588  HIS A ND1 1 
ATOM   4328 C CD2 . HIS A 1 629  ? 148.010 87.461  39.283  1.00 176.14 ? 588  HIS A CD2 1 
ATOM   4329 C CE1 . HIS A 1 629  ? 149.774 87.795  40.542  1.00 176.14 ? 588  HIS A CE1 1 
ATOM   4330 N NE2 . HIS A 1 629  ? 149.163 86.905  39.781  1.00 176.14 ? 588  HIS A NE2 1 
ATOM   4331 N N   . ASP A 1 630  ? 148.277 91.242  36.428  1.00 177.21 ? 589  ASP A N   1 
ATOM   4332 C CA  . ASP A 1 630  ? 149.562 91.748  35.956  1.00 177.21 ? 589  ASP A CA  1 
ATOM   4333 C C   . ASP A 1 630  ? 149.662 93.265  36.078  1.00 177.21 ? 589  ASP A C   1 
ATOM   4334 O O   . ASP A 1 630  ? 150.499 93.783  36.825  1.00 177.21 ? 589  ASP A O   1 
ATOM   4335 C CB  . ASP A 1 630  ? 149.787 91.304  34.511  1.00 177.21 ? 589  ASP A CB  1 
ATOM   4336 C CG  . ASP A 1 630  ? 149.486 89.834  34.305  1.00 177.21 ? 589  ASP A CG  1 
ATOM   4337 O OD1 . ASP A 1 630  ? 150.129 88.996  34.972  1.00 177.21 ? 589  ASP A OD1 1 
ATOM   4338 O OD2 . ASP A 1 630  ? 148.603 89.517  33.481  1.00 177.21 ? 589  ASP A OD2 1 
ATOM   4339 N N   . GLU A 1 631  ? 148.816 93.998  35.352  1.00 177.59 ? 590  GLU A N   1 
ATOM   4340 C CA  . GLU A 1 631  ? 148.956 95.455  35.309  1.00 177.59 ? 590  GLU A CA  1 
ATOM   4341 C C   . GLU A 1 631  ? 148.256 96.127  36.488  1.00 177.59 ? 590  GLU A C   1 
ATOM   4342 O O   . GLU A 1 631  ? 148.909 96.724  37.350  1.00 177.59 ? 590  GLU A O   1 
ATOM   4343 C CB  . GLU A 1 631  ? 148.421 95.989  33.977  1.00 177.59 ? 590  GLU A CB  1 
ATOM   4344 C CG  . GLU A 1 631  ? 149.150 95.449  32.757  1.00 177.59 ? 590  GLU A CG  1 
ATOM   4345 C CD  . GLU A 1 631  ? 148.451 95.794  31.459  1.00 177.59 ? 590  GLU A CD  1 
ATOM   4346 O OE1 . GLU A 1 631  ? 148.340 96.998  31.145  1.00 177.59 ? 590  GLU A OE1 1 
ATOM   4347 O OE2 . GLU A 1 631  ? 148.012 94.862  30.753  1.00 177.59 ? 590  GLU A OE2 1 
ATOM   4348 N N   . LEU A 1 632  ? 146.926 96.021  36.543  1.00 179.72 ? 591  LEU A N   1 
ATOM   4349 C CA  . LEU A 1 632  ? 146.117 96.648  37.594  1.00 179.72 ? 591  LEU A CA  1 
ATOM   4350 C C   . LEU A 1 632  ? 146.469 98.122  37.773  1.00 179.72 ? 591  LEU A C   1 
ATOM   4351 O O   . LEU A 1 632  ? 146.581 98.628  38.892  1.00 179.72 ? 591  LEU A O   1 
ATOM   4352 C CB  . LEU A 1 632  ? 146.252 95.893  38.917  1.00 179.72 ? 591  LEU A CB  1 
ATOM   4353 C CG  . LEU A 1 632  ? 145.275 94.739  39.144  1.00 179.72 ? 591  LEU A CG  1 
ATOM   4354 C CD1 . LEU A 1 632  ? 145.544 93.597  38.184  1.00 179.72 ? 591  LEU A CD1 1 
ATOM   4355 C CD2 . LEU A 1 632  ? 145.358 94.263  40.583  1.00 179.72 ? 591  LEU A CD2 1 
ATOM   4356 N N   . PHE A 1 633  ? 146.641 98.821  36.658  1.00 179.34 ? 592  PHE A N   1 
ATOM   4357 C CA  . PHE A 1 633  ? 147.030 100.222 36.666  1.00 179.34 ? 592  PHE A CA  1 
ATOM   4358 C C   . PHE A 1 633  ? 145.806 101.123 36.528  1.00 179.34 ? 592  PHE A C   1 
ATOM   4359 O O   . PHE A 1 633  ? 144.745 100.705 36.058  1.00 179.34 ? 592  PHE A O   1 
ATOM   4360 C CB  . PHE A 1 633  ? 148.033 100.513 35.544  1.00 179.34 ? 592  PHE A CB  1 
ATOM   4361 C CG  . PHE A 1 633  ? 147.422 100.539 34.169  1.00 179.34 ? 592  PHE A CG  1 
ATOM   4362 C CD1 . PHE A 1 633  ? 146.879 99.392  33.611  1.00 179.34 ? 592  PHE A CD1 1 
ATOM   4363 C CD2 . PHE A 1 633  ? 147.393 101.712 33.435  1.00 179.34 ? 592  PHE A CD2 1 
ATOM   4364 C CE1 . PHE A 1 633  ? 146.319 99.416  32.350  1.00 179.34 ? 592  PHE A CE1 1 
ATOM   4365 C CE2 . PHE A 1 633  ? 146.834 101.742 32.173  1.00 179.34 ? 592  PHE A CE2 1 
ATOM   4366 C CZ  . PHE A 1 633  ? 146.297 100.592 31.631  1.00 179.34 ? 592  PHE A CZ  1 
ATOM   4367 N N   . SER A 1 634  ? 145.972 102.372 36.965  1.00 179.01 ? 593  SER A N   1 
ATOM   4368 C CA  . SER A 1 634  ? 144.939 103.406 36.906  1.00 179.01 ? 593  SER A CA  1 
ATOM   4369 C C   . SER A 1 634  ? 143.689 103.032 37.695  1.00 179.01 ? 593  SER A C   1 
ATOM   4370 O O   . SER A 1 634  ? 142.617 103.603 37.473  1.00 179.01 ? 593  SER A O   1 
ATOM   4371 C CB  . SER A 1 634  ? 144.564 103.738 35.456  1.00 179.01 ? 593  SER A CB  1 
ATOM   4372 O OG  . SER A 1 634  ? 143.562 102.859 34.974  1.00 179.01 ? 593  SER A OG  1 
ATOM   4373 N N   . LYS A 1 635  ? 143.803 102.080 38.618  1.00 174.06 ? 594  LYS A N   1 
ATOM   4374 C CA  . LYS A 1 635  ? 142.678 101.644 39.428  1.00 174.06 ? 594  LYS A CA  1 
ATOM   4375 C C   . LYS A 1 635  ? 143.130 101.478 40.870  1.00 174.06 ? 594  LYS A C   1 
ATOM   4376 O O   . LYS A 1 635  ? 144.207 100.934 41.132  1.00 174.06 ? 594  LYS A O   1 
ATOM   4377 C CB  . LYS A 1 635  ? 142.088 100.325 38.907  1.00 174.06 ? 594  LYS A CB  1 
ATOM   4378 C CG  . LYS A 1 635  ? 141.527 100.409 37.496  1.00 174.06 ? 594  LYS A CG  1 
ATOM   4379 C CD  . LYS A 1 635  ? 141.359 99.031  36.878  1.00 174.06 ? 594  LYS A CD  1 
ATOM   4380 C CE  . LYS A 1 635  ? 142.612 98.189  37.043  1.00 174.06 ? 594  LYS A CE  1 
ATOM   4381 N NZ  . LYS A 1 635  ? 142.444 96.832  36.457  1.00 174.06 ? 594  LYS A NZ  1 
ATOM   4382 N N   . GLY A 1 636  ? 142.301 101.947 41.800  1.00 171.91 ? 595  GLY A N   1 
ATOM   4383 C CA  . GLY A 1 636  ? 142.593 101.819 43.213  1.00 171.91 ? 595  GLY A CA  1 
ATOM   4384 C C   . GLY A 1 636  ? 143.842 102.556 43.650  1.00 171.91 ? 595  GLY A C   1 
ATOM   4385 O O   . GLY A 1 636  ? 144.658 102.018 44.405  1.00 171.91 ? 595  GLY A O   1 
ATOM   4386 N N   . GLU A 1 637  ? 144.002 103.795 43.182  1.00 171.64 ? 596  GLU A N   1 
ATOM   4387 C CA  . GLU A 1 637  ? 145.163 104.599 43.541  1.00 171.64 ? 596  GLU A CA  1 
ATOM   4388 C C   . GLU A 1 637  ? 145.205 104.947 45.023  1.00 171.64 ? 596  GLU A C   1 
ATOM   4389 O O   . GLU A 1 637  ? 146.260 105.363 45.511  1.00 171.64 ? 596  GLU A O   1 
ATOM   4390 C CB  . GLU A 1 637  ? 145.185 105.884 42.711  1.00 171.64 ? 596  GLU A CB  1 
ATOM   4391 C CG  . GLU A 1 637  ? 144.075 106.863 43.060  1.00 171.64 ? 596  GLU A CG  1 
ATOM   4392 C CD  . GLU A 1 637  ? 142.774 106.563 42.337  1.00 171.64 ? 596  GLU A CD  1 
ATOM   4393 O OE1 . GLU A 1 637  ? 142.628 105.444 41.801  1.00 171.64 ? 596  GLU A OE1 1 
ATOM   4394 O OE2 . GLU A 1 637  ? 141.894 107.448 42.309  1.00 171.64 ? 596  GLU A OE2 1 
ATOM   4395 N N   . ASN A 1 638  ? 144.094 104.796 45.739  1.00 172.21 ? 597  ASN A N   1 
ATOM   4396 C CA  . ASN A 1 638  ? 144.080 105.072 47.167  1.00 172.21 ? 597  ASN A CA  1 
ATOM   4397 C C   . ASN A 1 638  ? 144.977 104.090 47.910  1.00 172.21 ? 597  ASN A C   1 
ATOM   4398 O O   . ASN A 1 638  ? 145.001 102.893 47.609  1.00 172.21 ? 597  ASN A O   1 
ATOM   4399 C CB  . ASN A 1 638  ? 142.653 104.994 47.708  1.00 172.21 ? 597  ASN A CB  1 
ATOM   4400 C CG  . ASN A 1 638  ? 142.565 105.354 49.177  1.00 172.21 ? 597  ASN A CG  1 
ATOM   4401 O OD1 . ASN A 1 638  ? 143.459 105.998 49.727  1.00 172.21 ? 597  ASN A OD1 1 
ATOM   4402 N ND2 . ASN A 1 638  ? 141.483 104.936 49.823  1.00 172.21 ? 597  ASN A ND2 1 
ATOM   4403 N N   . GLY A 1 639  ? 145.720 104.605 48.885  1.00 174.14 ? 598  GLY A N   1 
ATOM   4404 C CA  . GLY A 1 639  ? 146.619 103.785 49.676  1.00 174.14 ? 598  GLY A CA  1 
ATOM   4405 C C   . GLY A 1 639  ? 146.028 103.364 51.007  1.00 174.14 ? 598  GLY A C   1 
ATOM   4406 O O   . GLY A 1 639  ? 144.828 103.115 51.111  1.00 174.14 ? 598  GLY A O   1 
ATOM   4407 N N   . LYS A 1 717  ? 143.601 105.694 108.216 1.00 171.31 ? 676  LYS A N   1 
ATOM   4408 C CA  . LYS A 1 717  ? 142.558 106.706 108.328 1.00 171.31 ? 676  LYS A CA  1 
ATOM   4409 C C   . LYS A 1 717  ? 143.040 108.053 107.799 1.00 171.31 ? 676  LYS A C   1 
ATOM   4410 O O   . LYS A 1 717  ? 144.236 108.344 107.804 1.00 171.31 ? 676  LYS A O   1 
ATOM   4411 C CB  . LYS A 1 717  ? 142.097 106.843 109.780 1.00 171.31 ? 676  LYS A CB  1 
ATOM   4412 C CG  . LYS A 1 717  ? 141.246 105.682 110.267 1.00 171.31 ? 676  LYS A CG  1 
ATOM   4413 C CD  . LYS A 1 717  ? 139.837 105.754 109.699 1.00 171.31 ? 676  LYS A CD  1 
ATOM   4414 C CE  . LYS A 1 717  ? 138.912 106.539 110.614 1.00 171.31 ? 676  LYS A CE  1 
ATOM   4415 N NZ  . LYS A 1 717  ? 138.583 105.779 111.849 1.00 171.31 ? 676  LYS A NZ  1 
ATOM   4416 N N   . LEU A 1 718  ? 142.096 108.871 107.342 1.00 165.06 ? 677  LEU A N   1 
ATOM   4417 C CA  . LEU A 1 718  ? 142.438 110.153 106.744 1.00 165.06 ? 677  LEU A CA  1 
ATOM   4418 C C   . LEU A 1 718  ? 142.836 111.161 107.816 1.00 165.06 ? 677  LEU A C   1 
ATOM   4419 O O   . LEU A 1 718  ? 142.288 111.166 108.921 1.00 165.06 ? 677  LEU A O   1 
ATOM   4420 C CB  . LEU A 1 718  ? 141.258 110.682 105.928 1.00 165.06 ? 677  LEU A CB  1 
ATOM   4421 C CG  . LEU A 1 718  ? 141.508 111.945 105.110 1.00 165.06 ? 677  LEU A CG  1 
ATOM   4422 C CD1 . LEU A 1 718  ? 142.364 111.600 103.907 1.00 165.06 ? 677  LEU A CD1 1 
ATOM   4423 C CD2 . LEU A 1 718  ? 140.193 112.570 104.674 1.00 165.06 ? 677  LEU A CD2 1 
ATOM   4424 N N   . ALA A 1 719  ? 143.798 112.019 107.480 1.00 163.48 ? 678  ALA A N   1 
ATOM   4425 C CA  . ALA A 1 719  ? 144.279 113.019 108.419 1.00 163.48 ? 678  ALA A CA  1 
ATOM   4426 C C   . ALA A 1 719  ? 143.214 114.084 108.670 1.00 163.48 ? 678  ALA A C   1 
ATOM   4427 O O   . ALA A 1 719  ? 142.317 114.312 107.855 1.00 163.48 ? 678  ALA A O   1 
ATOM   4428 C CB  . ALA A 1 719  ? 145.560 113.671 107.899 1.00 163.48 ? 678  ALA A CB  1 
ATOM   4429 N N   . PHE A 1 720  ? 143.329 114.742 109.824 1.00 159.94 ? 679  PHE A N   1 
ATOM   4430 C CA  . PHE A 1 720  ? 142.370 115.758 110.240 1.00 159.94 ? 679  PHE A CA  1 
ATOM   4431 C C   . PHE A 1 720  ? 142.957 117.157 110.339 1.00 159.94 ? 679  PHE A C   1 
ATOM   4432 O O   . PHE A 1 720  ? 142.230 118.129 110.124 1.00 159.94 ? 679  PHE A O   1 
ATOM   4433 C CB  . PHE A 1 720  ? 141.754 115.386 111.595 1.00 159.94 ? 679  PHE A CB  1 
ATOM   4434 C CG  . PHE A 1 720  ? 140.582 114.454 111.491 1.00 159.94 ? 679  PHE A CG  1 
ATOM   4435 C CD1 . PHE A 1 720  ? 139.581 114.682 110.564 1.00 159.94 ? 679  PHE A CD1 1 
ATOM   4436 C CD2 . PHE A 1 720  ? 140.483 113.349 112.321 1.00 159.94 ? 679  PHE A CD2 1 
ATOM   4437 C CE1 . PHE A 1 720  ? 138.501 113.826 110.467 1.00 159.94 ? 679  PHE A CE1 1 
ATOM   4438 C CE2 . PHE A 1 720  ? 139.405 112.490 112.228 1.00 159.94 ? 679  PHE A CE2 1 
ATOM   4439 C CZ  . PHE A 1 720  ? 138.413 112.729 111.300 1.00 159.94 ? 679  PHE A CZ  1 
ATOM   4440 N N   . LYS A 1 721  ? 144.245 117.285 110.669 1.00 156.13 ? 680  LYS A N   1 
ATOM   4441 C CA  . LYS A 1 721  ? 144.856 118.608 110.756 1.00 156.13 ? 680  LYS A CA  1 
ATOM   4442 C C   . LYS A 1 721  ? 144.878 119.298 109.397 1.00 156.13 ? 680  LYS A C   1 
ATOM   4443 O O   . LYS A 1 721  ? 144.593 120.498 109.295 1.00 156.13 ? 680  LYS A O   1 
ATOM   4444 C CB  . LYS A 1 721  ? 146.268 118.495 111.329 1.00 156.13 ? 680  LYS A CB  1 
ATOM   4445 C CG  . LYS A 1 721  ? 146.326 118.541 112.847 1.00 156.13 ? 680  LYS A CG  1 
ATOM   4446 C CD  . LYS A 1 721  ? 146.124 117.159 113.451 1.00 156.13 ? 680  LYS A CD  1 
ATOM   4447 C CE  . LYS A 1 721  ? 147.358 116.289 113.275 1.00 156.13 ? 680  LYS A CE  1 
ATOM   4448 N NZ  . LYS A 1 721  ? 147.199 114.958 113.921 1.00 156.13 ? 680  LYS A NZ  1 
ATOM   4449 N N   . ASP A 1 722  ? 145.218 118.554 108.341 1.00 149.99 ? 681  ASP A N   1 
ATOM   4450 C CA  . ASP A 1 722  ? 145.199 119.123 106.997 1.00 149.99 ? 681  ASP A CA  1 
ATOM   4451 C C   . ASP A 1 722  ? 143.790 119.538 106.598 1.00 149.99 ? 681  ASP A C   1 
ATOM   4452 O O   . ASP A 1 722  ? 143.598 120.578 105.956 1.00 149.99 ? 681  ASP A O   1 
ATOM   4453 C CB  . ASP A 1 722  ? 145.776 118.122 105.997 1.00 149.99 ? 681  ASP A CB  1 
ATOM   4454 C CG  . ASP A 1 722  ? 145.095 116.768 106.065 1.00 149.99 ? 681  ASP A CG  1 
ATOM   4455 O OD1 . ASP A 1 722  ? 144.243 116.571 106.956 1.00 149.99 ? 681  ASP A OD1 1 
ATOM   4456 O OD2 . ASP A 1 722  ? 145.414 115.898 105.227 1.00 149.99 ? 681  ASP A OD2 1 
ATOM   4457 N N   . GLN A 1 723  ? 142.792 118.733 106.966 1.00 142.25 ? 682  GLN A N   1 
ATOM   4458 C CA  . GLN A 1 723  ? 141.408 119.104 106.694 1.00 142.25 ? 682  GLN A CA  1 
ATOM   4459 C C   . GLN A 1 723  ? 141.032 120.383 107.426 1.00 142.25 ? 682  GLN A C   1 
ATOM   4460 O O   . GLN A 1 723  ? 140.341 121.244 106.870 1.00 142.25 ? 682  GLN A O   1 
ATOM   4461 C CB  . GLN A 1 723  ? 140.471 117.962 107.082 1.00 142.25 ? 682  GLN A CB  1 
ATOM   4462 C CG  . GLN A 1 723  ? 140.689 116.689 106.284 1.00 142.25 ? 682  GLN A CG  1 
ATOM   4463 C CD  . GLN A 1 723  ? 139.914 116.674 104.982 1.00 142.25 ? 682  GLN A CD  1 
ATOM   4464 O OE1 . GLN A 1 723  ? 138.841 116.077 104.891 1.00 142.25 ? 682  GLN A OE1 1 
ATOM   4465 N NE2 . GLN A 1 723  ? 140.454 117.332 103.962 1.00 142.25 ? 682  GLN A NE2 1 
ATOM   4466 N N   . ALA A 1 724  ? 141.486 120.532 108.674 1.00 139.34 ? 683  ALA A N   1 
ATOM   4467 C CA  . ALA A 1 724  ? 141.216 121.758 109.417 1.00 139.34 ? 683  ALA A CA  1 
ATOM   4468 C C   . ALA A 1 724  ? 141.872 122.964 108.756 1.00 139.34 ? 683  ALA A C   1 
ATOM   4469 O O   . ALA A 1 724  ? 141.264 124.036 108.659 1.00 139.34 ? 683  ALA A O   1 
ATOM   4470 C CB  . ALA A 1 724  ? 141.693 121.612 110.863 1.00 139.34 ? 683  ALA A CB  1 
ATOM   4471 N N   . ASN A 1 725  ? 143.117 122.810 108.299 1.00 129.93 ? 684  ASN A N   1 
ATOM   4472 C CA  . ASN A 1 725  ? 143.802 123.921 107.643 1.00 129.93 ? 684  ASN A CA  1 
ATOM   4473 C C   . ASN A 1 725  ? 143.106 124.312 106.345 1.00 129.93 ? 684  ASN A C   1 
ATOM   4474 O O   . ASN A 1 725  ? 142.940 125.503 106.053 1.00 129.93 ? 684  ASN A O   1 
ATOM   4475 C CB  . ASN A 1 725  ? 145.260 123.555 107.381 1.00 129.93 ? 684  ASN A CB  1 
ATOM   4476 C CG  . ASN A 1 725  ? 146.129 124.772 107.148 1.00 129.93 ? 684  ASN A CG  1 
ATOM   4477 O OD1 . ASN A 1 725  ? 145.676 125.908 107.288 1.00 129.93 ? 684  ASN A OD1 1 
ATOM   4478 N ND2 . ASN A 1 725  ? 147.386 124.542 106.789 1.00 129.93 ? 684  ASN A ND2 1 
ATOM   4479 N N   . SER A 1 726  ? 142.691 123.323 105.552 1.00 123.68 ? 685  SER A N   1 
ATOM   4480 C CA  . SER A 1 726  ? 141.997 123.624 104.303 1.00 123.68 ? 685  SER A CA  1 
ATOM   4481 C C   . SER A 1 726  ? 140.634 124.256 104.565 1.00 123.68 ? 685  SER A C   1 
ATOM   4482 O O   . SER A 1 726  ? 140.211 125.159 103.833 1.00 123.68 ? 685  SER A O   1 
ATOM   4483 C CB  . SER A 1 726  ? 141.863 122.354 103.468 1.00 123.68 ? 685  SER A CB  1 
ATOM   4484 O OG  . SER A 1 726  ? 140.987 121.431 104.087 1.00 123.68 ? 685  SER A OG  1 
ATOM   4485 N N   . PHE A 1 727  ? 139.934 123.795 105.606 1.00 114.57 ? 686  PHE A N   1 
ATOM   4486 C CA  . PHE A 1 727  ? 138.690 124.433 106.021 1.00 114.57 ? 686  PHE A CA  1 
ATOM   4487 C C   . PHE A 1 727  ? 138.926 125.894 106.382 1.00 114.57 ? 686  PHE A C   1 
ATOM   4488 O O   . PHE A 1 727  ? 138.175 126.778 105.953 1.00 114.57 ? 686  PHE A O   1 
ATOM   4489 C CB  . PHE A 1 727  ? 138.107 123.659 107.209 1.00 114.57 ? 686  PHE A CB  1 
ATOM   4490 C CG  . PHE A 1 727  ? 136.773 124.164 107.702 1.00 114.57 ? 686  PHE A CG  1 
ATOM   4491 C CD1 . PHE A 1 727  ? 135.990 125.015 106.945 1.00 114.57 ? 686  PHE A CD1 1 
ATOM   4492 C CD2 . PHE A 1 727  ? 136.290 123.749 108.932 1.00 114.57 ? 686  PHE A CD2 1 
ATOM   4493 C CE1 . PHE A 1 727  ? 134.770 125.464 107.414 1.00 114.57 ? 686  PHE A CE1 1 
ATOM   4494 C CE2 . PHE A 1 727  ? 135.072 124.192 109.404 1.00 114.57 ? 686  PHE A CE2 1 
ATOM   4495 C CZ  . PHE A 1 727  ? 134.310 125.049 108.642 1.00 114.57 ? 686  PHE A CZ  1 
ATOM   4496 N N   . TRP A 1 728  ? 139.976 126.167 107.155 1.00 111.88 ? 687  TRP A N   1 
ATOM   4497 C CA  . TRP A 1 728  ? 140.267 127.542 107.542 1.00 111.88 ? 687  TRP A CA  1 
ATOM   4498 C C   . TRP A 1 728  ? 140.599 128.399 106.327 1.00 111.88 ? 687  TRP A C   1 
ATOM   4499 O O   . TRP A 1 728  ? 140.188 129.563 106.248 1.00 111.88 ? 687  TRP A O   1 
ATOM   4500 C CB  . TRP A 1 728  ? 141.409 127.571 108.556 1.00 111.88 ? 687  TRP A CB  1 
ATOM   4501 C CG  . TRP A 1 728  ? 141.453 128.817 109.389 1.00 111.88 ? 687  TRP A CG  1 
ATOM   4502 C CD1 . TRP A 1 728  ? 142.522 129.645 109.566 1.00 111.88 ? 687  TRP A CD1 1 
ATOM   4503 C CD2 . TRP A 1 728  ? 140.383 129.374 110.166 1.00 111.88 ? 687  TRP A CD2 1 
ATOM   4504 N NE1 . TRP A 1 728  ? 142.186 130.683 110.400 1.00 111.88 ? 687  TRP A NE1 1 
ATOM   4505 C CE2 . TRP A 1 728  ? 140.878 130.540 110.781 1.00 111.88 ? 687  TRP A CE2 1 
ATOM   4506 C CE3 . TRP A 1 728  ? 139.056 129.001 110.400 1.00 111.88 ? 687  TRP A CE3 1 
ATOM   4507 C CZ2 . TRP A 1 728  ? 140.094 131.334 111.613 1.00 111.88 ? 687  TRP A CZ2 1 
ATOM   4508 C CZ3 . TRP A 1 728  ? 138.281 129.791 111.222 1.00 111.88 ? 687  TRP A CZ3 1 
ATOM   4509 C CH2 . TRP A 1 728  ? 138.801 130.944 111.820 1.00 111.88 ? 687  TRP A CH2 1 
ATOM   4510 N N   . ARG A 1 729  ? 141.334 127.839 105.364 1.00 102.23 ? 688  ARG A N   1 
ATOM   4511 C CA  . ARG A 1 729  ? 141.702 128.622 104.190 1.00 102.23 ? 688  ARG A CA  1 
ATOM   4512 C C   . ARG A 1 729  ? 140.501 128.887 103.288 1.00 102.23 ? 688  ARG A C   1 
ATOM   4513 O O   . ARG A 1 729  ? 140.395 129.976 102.714 1.00 102.23 ? 688  ARG A O   1 
ATOM   4514 C CB  . ARG A 1 729  ? 142.822 127.930 103.417 1.00 102.23 ? 688  ARG A CB  1 
ATOM   4515 C CG  . ARG A 1 729  ? 143.957 128.874 103.033 1.00 102.23 ? 688  ARG A CG  1 
ATOM   4516 C CD  . ARG A 1 729  ? 144.941 128.235 102.066 1.00 102.23 ? 688  ARG A CD  1 
ATOM   4517 N NE  . ARG A 1 729  ? 144.480 128.303 100.686 1.00 102.23 ? 688  ARG A NE  1 
ATOM   4518 C CZ  . ARG A 1 729  ? 145.213 127.967 99.634  1.00 102.23 ? 688  ARG A CZ  1 
ATOM   4519 N NH1 . ARG A 1 729  ? 146.454 127.528 99.769  1.00 102.23 ? 688  ARG A NH1 1 
ATOM   4520 N NH2 . ARG A 1 729  ? 144.686 128.066 98.417  1.00 102.23 ? 688  ARG A NH2 1 
ATOM   4521 N N   . LEU A 1 730  ? 139.585 127.922 103.151 1.00 97.54  ? 689  LEU A N   1 
ATOM   4522 C CA  . LEU A 1 730  ? 138.342 128.201 102.433 1.00 97.54  ? 689  LEU A CA  1 
ATOM   4523 C C   . LEU A 1 730  ? 137.511 129.254 103.149 1.00 97.54  ? 689  LEU A C   1 
ATOM   4524 O O   . LEU A 1 730  ? 136.911 130.122 102.505 1.00 97.54  ? 689  LEU A O   1 
ATOM   4525 C CB  . LEU A 1 730  ? 137.515 126.933 102.243 1.00 97.54  ? 689  LEU A CB  1 
ATOM   4526 C CG  . LEU A 1 730  ? 137.925 126.005 101.108 1.00 97.54  ? 689  LEU A CG  1 
ATOM   4527 C CD1 . LEU A 1 730  ? 137.058 124.773 101.109 1.00 97.54  ? 689  LEU A CD1 1 
ATOM   4528 C CD2 . LEU A 1 730  ? 137.819 126.727 99.783  1.00 97.54  ? 689  LEU A CD2 1 
ATOM   4529 N N   . ALA A 1 731  ? 137.442 129.185 104.479 1.00 93.81  ? 690  ALA A N   1 
ATOM   4530 C CA  . ALA A 1 731  ? 136.697 130.193 105.222 1.00 93.81  ? 690  ALA A CA  1 
ATOM   4531 C C   . ALA A 1 731  ? 137.284 131.578 104.997 1.00 93.81  ? 690  ALA A C   1 
ATOM   4532 O O   . ALA A 1 731  ? 136.547 132.548 104.788 1.00 93.81  ? 690  ALA A O   1 
ATOM   4533 C CB  . ALA A 1 731  ? 136.683 129.846 106.709 1.00 93.81  ? 690  ALA A CB  1 
ATOM   4534 N N   . LYS A 1 732  ? 138.613 131.687 105.028 1.00 91.58  ? 691  LYS A N   1 
ATOM   4535 C CA  . LYS A 1 732  ? 139.259 132.952 104.692 1.00 91.58  ? 691  LYS A CA  1 
ATOM   4536 C C   . LYS A 1 732  ? 138.950 133.356 103.254 1.00 91.58  ? 691  LYS A C   1 
ATOM   4537 O O   . LYS A 1 732  ? 138.831 134.546 102.945 1.00 91.58  ? 691  LYS A O   1 
ATOM   4538 C CB  . LYS A 1 732  ? 140.767 132.842 104.913 1.00 91.58  ? 691  LYS A CB  1 
ATOM   4539 C CG  . LYS A 1 732  ? 141.538 134.128 104.673 1.00 91.58  ? 691  LYS A CG  1 
ATOM   4540 C CD  . LYS A 1 732  ? 140.991 135.268 105.514 1.00 91.58  ? 691  LYS A CD  1 
ATOM   4541 C CE  . LYS A 1 732  ? 141.688 136.578 105.188 1.00 91.58  ? 691  LYS A CE  1 
ATOM   4542 N NZ  . LYS A 1 732  ? 141.135 137.709 105.981 1.00 91.58  ? 691  LYS A NZ  1 
ATOM   4543 N N   . MET A 1 733  ? 138.818 132.372 102.362 1.00 86.93  ? 692  MET A N   1 
ATOM   4544 C CA  . MET A 1 733  ? 138.425 132.651 100.986 1.00 86.93  ? 692  MET A CA  1 
ATOM   4545 C C   . MET A 1 733  ? 136.967 133.078 100.896 1.00 86.93  ? 692  MET A C   1 
ATOM   4546 O O   . MET A 1 733  ? 136.582 133.775 99.950  1.00 86.93  ? 692  MET A O   1 
ATOM   4547 C CB  . MET A 1 733  ? 138.671 131.418 100.118 1.00 86.93  ? 692  MET A CB  1 
ATOM   4548 C CG  . MET A 1 733  ? 138.560 131.658 98.625  1.00 86.93  ? 692  MET A CG  1 
ATOM   4549 S SD  . MET A 1 733  ? 139.264 130.303 97.668  1.00 86.93  ? 692  MET A SD  1 
ATOM   4550 C CE  . MET A 1 733  ? 140.584 129.771 98.753  1.00 86.93  ? 692  MET A CE  1 
ATOM   4551 N N   . ASN A 1 734  ? 136.149 132.675 101.862 1.00 77.54  ? 693  ASN A N   1 
ATOM   4552 C CA  . ASN A 1 734  ? 134.740 133.032 101.909 1.00 77.54  ? 693  ASN A CA  1 
ATOM   4553 C C   . ASN A 1 734  ? 134.479 134.274 102.748 1.00 77.54  ? 693  ASN A C   1 
ATOM   4554 O O   . ASN A 1 734  ? 133.318 134.585 103.028 1.00 77.54  ? 693  ASN A O   1 
ATOM   4555 C CB  . ASN A 1 734  ? 133.922 131.859 102.448 1.00 77.54  ? 693  ASN A CB  1 
ATOM   4556 C CG  . ASN A 1 734  ? 132.529 131.808 101.868 1.00 77.54  ? 693  ASN A CG  1 
ATOM   4557 O OD1 . ASN A 1 734  ? 132.128 132.690 101.114 1.00 77.54  ? 693  ASN A OD1 1 
ATOM   4558 N ND2 . ASN A 1 734  ? 131.784 130.766 102.210 1.00 77.54  ? 693  ASN A ND2 1 
ATOM   4559 N N   . SER A 1 735  ? 135.530 134.984 103.150 1.00 73.48  ? 694  SER A N   1 
ATOM   4560 C CA  . SER A 1 735  ? 135.389 136.154 104.016 1.00 73.48  ? 694  SER A CA  1 
ATOM   4561 C C   . SER A 1 735  ? 134.448 137.231 103.481 1.00 73.48  ? 694  SER A C   1 
ATOM   4562 O O   . SER A 1 735  ? 133.658 137.762 104.275 1.00 73.48  ? 694  SER A O   1 
ATOM   4563 C CB  . SER A 1 735  ? 136.779 136.736 104.306 1.00 73.48  ? 694  SER A CB  1 
ATOM   4564 O OG  . SER A 1 735  ? 137.583 136.769 103.142 1.00 73.48  ? 694  SER A OG  1 
ATOM   4565 N N   . PRO A 1 736  ? 134.463 137.604 102.195 1.00 69.54  ? 695  PRO A N   1 
ATOM   4566 C CA  . PRO A 1 736  ? 133.612 138.728 101.764 1.00 69.54  ? 695  PRO A CA  1 
ATOM   4567 C C   . PRO A 1 736  ? 132.126 138.504 101.980 1.00 69.54  ? 695  PRO A C   1 
ATOM   4568 O O   . PRO A 1 736  ? 131.365 139.479 101.973 1.00 69.54  ? 695  PRO A O   1 
ATOM   4569 C CB  . PRO A 1 736  ? 133.940 138.869 100.271 1.00 69.54  ? 695  PRO A CB  1 
ATOM   4570 C CG  . PRO A 1 736  ? 134.554 137.582 99.885  1.00 69.54  ? 695  PRO A CG  1 
ATOM   4571 C CD  . PRO A 1 736  ? 135.308 137.133 101.084 1.00 69.54  ? 695  PRO A CD  1 
ATOM   4572 N N   . GLU A 1 737  ? 131.683 137.264 102.171 1.00 69.02  ? 696  GLU A N   1 
ATOM   4573 C CA  . GLU A 1 737  ? 130.275 136.966 102.392 1.00 69.02  ? 696  GLU A CA  1 
ATOM   4574 C C   . GLU A 1 737  ? 129.892 137.004 103.867 1.00 69.02  ? 696  GLU A C   1 
ATOM   4575 O O   . GLU A 1 737  ? 128.747 136.677 104.202 1.00 69.02  ? 696  GLU A O   1 
ATOM   4576 C CB  . GLU A 1 737  ? 129.926 135.598 101.805 1.00 69.02  ? 696  GLU A CB  1 
ATOM   4577 C CG  . GLU A 1 737  ? 130.500 135.338 100.423 1.00 69.02  ? 696  GLU A CG  1 
ATOM   4578 C CD  . GLU A 1 737  ? 130.278 136.490 99.469  1.00 69.02  ? 696  GLU A CD  1 
ATOM   4579 O OE1 . GLU A 1 737  ? 129.109 136.875 99.267  1.00 69.02  ? 696  GLU A OE1 1 
ATOM   4580 O OE2 . GLU A 1 737  ? 131.270 137.007 98.918  1.00 69.02  ? 696  GLU A OE2 1 
ATOM   4581 N N   . TRP A 1 738  ? 130.816 137.421 104.743 1.00 66.03  ? 697  TRP A N   1 
ATOM   4582 C CA  . TRP A 1 738  ? 130.644 137.213 106.180 1.00 66.03  ? 697  TRP A CA  1 
ATOM   4583 C C   . TRP A 1 738  ? 129.303 137.742 106.666 1.00 66.03  ? 697  TRP A C   1 
ATOM   4584 O O   . TRP A 1 738  ? 128.582 137.042 107.387 1.00 66.03  ? 697  TRP A O   1 
ATOM   4585 C CB  . TRP A 1 738  ? 131.793 137.863 106.954 1.00 66.03  ? 697  TRP A CB  1 
ATOM   4586 C CG  . TRP A 1 738  ? 131.925 139.356 106.778 1.00 66.03  ? 697  TRP A CG  1 
ATOM   4587 C CD1 . TRP A 1 738  ? 132.687 140.009 105.856 1.00 66.03  ? 697  TRP A CD1 1 
ATOM   4588 C CD2 . TRP A 1 738  ? 131.317 140.374 107.585 1.00 66.03  ? 697  TRP A CD2 1 
ATOM   4589 N NE1 . TRP A 1 738  ? 132.569 141.368 106.017 1.00 66.03  ? 697  TRP A NE1 1 
ATOM   4590 C CE2 . TRP A 1 738  ? 131.735 141.617 107.074 1.00 66.03  ? 697  TRP A CE2 1 
ATOM   4591 C CE3 . TRP A 1 738  ? 130.452 140.353 108.681 1.00 66.03  ? 697  TRP A CE3 1 
ATOM   4592 C CZ2 . TRP A 1 738  ? 131.317 142.827 107.620 1.00 66.03  ? 697  TRP A CZ2 1 
ATOM   4593 C CZ3 . TRP A 1 738  ? 130.036 141.555 109.221 1.00 66.03  ? 697  TRP A CZ3 1 
ATOM   4594 C CH2 . TRP A 1 738  ? 130.470 142.774 108.691 1.00 66.03  ? 697  TRP A CH2 1 
ATOM   4595 N N   . LYS A 1 739  ? 128.939 138.961 106.253 1.00 63.90  ? 698  LYS A N   1 
ATOM   4596 C CA  . LYS A 1 739  ? 127.649 139.528 106.634 1.00 63.90  ? 698  LYS A CA  1 
ATOM   4597 C C   . LYS A 1 739  ? 126.537 138.508 106.464 1.00 63.90  ? 698  LYS A C   1 
ATOM   4598 O O   . LYS A 1 739  ? 125.893 138.108 107.442 1.00 63.90  ? 698  LYS A O   1 
ATOM   4599 C CB  . LYS A 1 739  ? 127.353 140.779 105.807 1.00 63.90  ? 698  LYS A CB  1 
ATOM   4600 C CG  . LYS A 1 739  ? 128.347 141.906 105.994 1.00 63.90  ? 698  LYS A CG  1 
ATOM   4601 C CD  . LYS A 1 739  ? 128.081 143.046 105.024 1.00 63.90  ? 698  LYS A CD  1 
ATOM   4602 C CE  . LYS A 1 739  ? 128.184 142.581 103.582 1.00 63.90  ? 698  LYS A CE  1 
ATOM   4603 N NZ  . LYS A 1 739  ? 127.911 143.688 102.624 1.00 63.90  ? 698  LYS A NZ  1 
ATOM   4604 N N   . TYR A 1 740  ? 126.342 138.028 105.232 1.00 60.96  ? 699  TYR A N   1 
ATOM   4605 C CA  . TYR A 1 740  ? 125.283 137.059 104.977 1.00 60.96  ? 699  TYR A CA  1 
ATOM   4606 C C   . TYR A 1 740  ? 125.369 135.895 105.947 1.00 60.96  ? 699  TYR A C   1 
ATOM   4607 O O   . TYR A 1 740  ? 124.382 135.566 106.621 1.00 60.96  ? 699  TYR A O   1 
ATOM   4608 C CB  . TYR A 1 740  ? 125.363 136.560 103.537 1.00 60.96  ? 699  TYR A CB  1 
ATOM   4609 C CG  . TYR A 1 740  ? 125.407 137.660 102.508 1.00 60.96  ? 699  TYR A CG  1 
ATOM   4610 C CD1 . TYR A 1 740  ? 124.323 138.503 102.319 1.00 60.96  ? 699  TYR A CD1 1 
ATOM   4611 C CD2 . TYR A 1 740  ? 126.534 137.858 101.726 1.00 60.96  ? 699  TYR A CD2 1 
ATOM   4612 C CE1 . TYR A 1 740  ? 124.359 139.509 101.377 1.00 60.96  ? 699  TYR A CE1 1 
ATOM   4613 C CE2 . TYR A 1 740  ? 126.580 138.863 100.785 1.00 60.96  ? 699  TYR A CE2 1 
ATOM   4614 C CZ  . TYR A 1 740  ? 125.491 139.685 100.614 1.00 60.96  ? 699  TYR A CZ  1 
ATOM   4615 O OH  . TYR A 1 740  ? 125.533 140.689 99.673  1.00 60.96  ? 699  TYR A OH  1 
ATOM   4616 N N   . ALA A 1 741  ? 126.563 135.315 106.095 1.00 56.28  ? 700  ALA A N   1 
ATOM   4617 C CA  . ALA A 1 741  ? 126.723 134.186 107.001 1.00 56.28  ? 700  ALA A CA  1 
ATOM   4618 C C   . ALA A 1 741  ? 126.185 134.523 108.381 1.00 56.28  ? 700  ALA A C   1 
ATOM   4619 O O   . ALA A 1 741  ? 125.314 133.812 108.901 1.00 56.28  ? 700  ALA A O   1 
ATOM   4620 C CB  . ALA A 1 741  ? 128.192 133.777 107.082 1.00 56.28  ? 700  ALA A CB  1 
ATOM   4621 N N   . LEU A 1 742  ? 126.625 135.649 108.951 1.00 56.17  ? 701  LEU A N   1 
ATOM   4622 C CA  . LEU A 1 742  ? 126.142 136.036 110.271 1.00 56.17  ? 701  LEU A CA  1 
ATOM   4623 C C   . LEU A 1 742  ? 124.625 136.063 110.299 1.00 56.17  ? 701  LEU A C   1 
ATOM   4624 O O   . LEU A 1 742  ? 124.000 135.396 111.132 1.00 56.17  ? 701  LEU A O   1 
ATOM   4625 C CB  . LEU A 1 742  ? 126.716 137.394 110.680 1.00 56.17  ? 701  LEU A CB  1 
ATOM   4626 C CG  . LEU A 1 742  ? 128.091 137.427 111.357 1.00 56.17  ? 701  LEU A CG  1 
ATOM   4627 C CD1 . LEU A 1 742  ? 128.014 136.718 112.694 1.00 56.17  ? 701  LEU A CD1 1 
ATOM   4628 C CD2 . LEU A 1 742  ? 129.186 136.816 110.501 1.00 56.17  ? 701  LEU A CD2 1 
ATOM   4629 N N   . LEU A 1 743  ? 124.008 136.764 109.346 1.00 54.97  ? 702  LEU A N   1 
ATOM   4630 C CA  . LEU A 1 743  ? 122.554 136.811 109.338 1.00 54.97  ? 702  LEU A CA  1 
ATOM   4631 C C   . LEU A 1 743  ? 121.983 135.411 109.206 1.00 54.97  ? 702  LEU A C   1 
ATOM   4632 O O   . LEU A 1 743  ? 121.120 135.009 109.996 1.00 54.97  ? 702  LEU A O   1 
ATOM   4633 C CB  . LEU A 1 743  ? 122.049 137.716 108.218 1.00 54.97  ? 702  LEU A CB  1 
ATOM   4634 C CG  . LEU A 1 743  ? 121.971 139.199 108.580 1.00 54.97  ? 702  LEU A CG  1 
ATOM   4635 C CD1 . LEU A 1 743  ? 123.338 139.847 108.521 1.00 54.97  ? 702  LEU A CD1 1 
ATOM   4636 C CD2 . LEU A 1 743  ? 120.988 139.929 107.686 1.00 54.97  ? 702  LEU A CD2 1 
ATOM   4637 N N   . GLY A 1 744  ? 122.517 134.624 108.271 1.00 52.71  ? 703  GLY A N   1 
ATOM   4638 C CA  . GLY A 1 744  ? 122.078 133.248 108.164 1.00 52.71  ? 703  GLY A CA  1 
ATOM   4639 C C   . GLY A 1 744  ? 122.260 132.511 109.472 1.00 52.71  ? 703  GLY A C   1 
ATOM   4640 O O   . GLY A 1 744  ? 121.330 131.865 109.965 1.00 52.71  ? 703  GLY A O   1 
ATOM   4641 N N   . SER A 1 745  ? 123.432 132.671 110.093 1.00 51.79  ? 704  SER A N   1 
ATOM   4642 C CA  . SER A 1 745  ? 123.668 132.045 111.386 1.00 51.79  ? 704  SER A CA  1 
ATOM   4643 C C   . SER A 1 745  ? 122.568 132.408 112.366 1.00 51.79  ? 704  SER A C   1 
ATOM   4644 O O   . SER A 1 745  ? 121.980 131.525 113.002 1.00 51.79  ? 704  SER A O   1 
ATOM   4645 C CB  . SER A 1 745  ? 125.031 132.458 111.931 1.00 51.79  ? 704  SER A CB  1 
ATOM   4646 O OG  . SER A 1 745  ? 125.236 131.928 113.226 1.00 51.79  ? 704  SER A OG  1 
ATOM   4647 N N   . VAL A 1 746  ? 122.222 133.695 112.443 1.00 49.79  ? 705  VAL A N   1 
ATOM   4648 C CA  . VAL A 1 746  ? 121.167 134.108 113.361 1.00 49.79  ? 705  VAL A CA  1 
ATOM   4649 C C   . VAL A 1 746  ? 119.894 133.339 113.058 1.00 49.79  ? 705  VAL A C   1 
ATOM   4650 O O   . VAL A 1 746  ? 119.342 132.651 113.928 1.00 49.79  ? 705  VAL A O   1 
ATOM   4651 C CB  . VAL A 1 746  ? 120.945 135.626 113.282 1.00 49.79  ? 705  VAL A CB  1 
ATOM   4652 C CG1 . VAL A 1 746  ? 119.607 135.993 113.890 1.00 49.79  ? 705  VAL A CG1 1 
ATOM   4653 C CG2 . VAL A 1 746  ? 122.068 136.354 113.995 1.00 49.79  ? 705  VAL A CG2 1 
ATOM   4654 N N   . GLY A 1 747  ? 119.481 133.342 111.789 1.00 49.51  ? 706  GLY A N   1 
ATOM   4655 C CA  . GLY A 1 747  ? 118.278 132.620 111.432 1.00 49.51  ? 706  GLY A CA  1 
ATOM   4656 C C   . GLY A 1 747  ? 118.355 131.179 111.881 1.00 49.51  ? 706  GLY A C   1 
ATOM   4657 O O   . GLY A 1 747  ? 117.433 130.671 112.530 1.00 49.51  ? 706  GLY A O   1 
ATOM   4658 N N   . SER A 1 748  ? 119.505 130.542 111.650 1.00 48.27  ? 707  SER A N   1 
ATOM   4659 C CA  . SER A 1 748  ? 119.652 129.143 112.018 1.00 48.27  ? 707  SER A CA  1 
ATOM   4660 C C   . SER A 1 748  ? 119.304 128.934 113.482 1.00 48.27  ? 707  SER A C   1 
ATOM   4661 O O   . SER A 1 748  ? 118.412 128.137 113.803 1.00 48.27  ? 707  SER A O   1 
ATOM   4662 C CB  . SER A 1 748  ? 121.071 128.669 111.724 1.00 48.27  ? 707  SER A CB  1 
ATOM   4663 O OG  . SER A 1 748  ? 121.994 129.331 112.562 1.00 48.27  ? 707  SER A OG  1 
ATOM   4664 N N   . VAL A 1 749  ? 119.923 129.709 114.382 1.00 47.95  ? 708  VAL A N   1 
ATOM   4665 C CA  . VAL A 1 749  ? 119.686 129.441 115.798 1.00 47.95  ? 708  VAL A CA  1 
ATOM   4666 C C   . VAL A 1 749  ? 118.213 129.625 116.111 1.00 47.95  ? 708  VAL A C   1 
ATOM   4667 O O   . VAL A 1 749  ? 117.593 128.778 116.767 1.00 47.95  ? 708  VAL A O   1 
ATOM   4668 C CB  . VAL A 1 749  ? 120.587 130.305 116.708 1.00 47.95  ? 708  VAL A CB  1 
ATOM   4669 C CG1 . VAL A 1 749  ? 122.039 130.128 116.344 1.00 47.95  ? 708  VAL A CG1 1 
ATOM   4670 C CG2 . VAL A 1 749  ? 120.200 131.769 116.697 1.00 47.95  ? 708  VAL A CG2 1 
ATOM   4671 N N   . ILE A 1 750  ? 117.603 130.673 115.555 1.00 47.52  ? 709  ILE A N   1 
ATOM   4672 C CA  . ILE A 1 750  ? 116.200 130.911 115.848 1.00 47.52  ? 709  ILE A CA  1 
ATOM   4673 C C   . ILE A 1 750  ? 115.364 129.752 115.344 1.00 47.52  ? 709  ILE A C   1 
ATOM   4674 O O   . ILE A 1 750  ? 114.516 129.226 116.074 1.00 47.52  ? 709  ILE A O   1 
ATOM   4675 C CB  . ILE A 1 750  ? 115.752 132.262 115.272 1.00 47.52  ? 709  ILE A CB  1 
ATOM   4676 C CG1 . ILE A 1 750  ? 116.585 133.368 115.921 1.00 47.52  ? 709  ILE A CG1 1 
ATOM   4677 C CG2 . ILE A 1 750  ? 114.272 132.475 115.493 1.00 47.52  ? 709  ILE A CG2 1 
ATOM   4678 C CD1 . ILE A 1 750  ? 116.106 134.751 115.644 1.00 47.52  ? 709  ILE A CD1 1 
ATOM   4679 N N   . CYS A 1 751  ? 115.653 129.270 114.132 1.00 48.20  ? 710  CYS A N   1 
ATOM   4680 C CA  . CYS A 1 751  ? 114.933 128.107 113.634 1.00 48.20  ? 710  CYS A CA  1 
ATOM   4681 C C   . CYS A 1 751  ? 115.049 126.955 114.618 1.00 48.20  ? 710  CYS A C   1 
ATOM   4682 O O   . CYS A 1 751  ? 114.037 126.369 115.028 1.00 48.20  ? 710  CYS A O   1 
ATOM   4683 C CB  . CYS A 1 751  ? 115.456 127.710 112.257 1.00 48.20  ? 710  CYS A CB  1 
ATOM   4684 S SG  . CYS A 1 751  ? 115.004 128.865 110.956 1.00 48.20  ? 710  CYS A SG  1 
ATOM   4685 N N   . GLY A 1 752  ? 116.269 126.684 115.088 1.00 47.91  ? 711  GLY A N   1 
ATOM   4686 C CA  . GLY A 1 752  ? 116.440 125.618 116.057 1.00 47.91  ? 711  GLY A CA  1 
ATOM   4687 C C   . GLY A 1 752  ? 115.574 125.836 117.279 1.00 47.91  ? 711  GLY A C   1 
ATOM   4688 O O   . GLY A 1 752  ? 114.829 124.941 117.691 1.00 47.91  ? 711  GLY A O   1 
ATOM   4689 N N   . SER A 1 753  ? 115.587 127.060 117.814 1.00 45.35  ? 712  SER A N   1 
ATOM   4690 C CA  . SER A 1 753  ? 114.763 127.356 118.975 1.00 45.35  ? 712  SER A CA  1 
ATOM   4691 C C   . SER A 1 753  ? 113.308 127.024 118.698 1.00 45.35  ? 712  SER A C   1 
ATOM   4692 O O   . SER A 1 753  ? 112.668 126.321 119.490 1.00 45.35  ? 712  SER A O   1 
ATOM   4693 C CB  . SER A 1 753  ? 114.916 128.820 119.375 1.00 45.35  ? 712  SER A CB  1 
ATOM   4694 O OG  . SER A 1 753  ? 116.268 129.126 119.663 1.00 45.35  ? 712  SER A OG  1 
ATOM   4695 N N   . LEU A 1 754  ? 112.792 127.455 117.541 1.00 45.56  ? 713  LEU A N   1 
ATOM   4696 C CA  . LEU A 1 754  ? 111.398 127.170 117.225 1.00 45.56  ? 713  LEU A CA  1 
ATOM   4697 C C   . LEU A 1 754  ? 111.108 125.687 117.344 1.00 45.56  ? 713  LEU A C   1 
ATOM   4698 O O   . LEU A 1 754  ? 110.148 125.293 118.018 1.00 45.56  ? 713  LEU A O   1 
ATOM   4699 C CB  . LEU A 1 754  ? 111.035 127.684 115.832 1.00 45.56  ? 713  LEU A CB  1 
ATOM   4700 C CG  . LEU A 1 754  ? 110.575 129.138 115.700 1.00 45.56  ? 713  LEU A CG  1 
ATOM   4701 C CD1 . LEU A 1 754  ? 109.269 129.310 116.443 1.00 45.56  ? 713  LEU A CD1 1 
ATOM   4702 C CD2 . LEU A 1 754  ? 111.585 130.123 116.221 1.00 45.56  ? 713  LEU A CD2 1 
ATOM   4703 N N   . SER A 1 755  ? 111.971 124.843 116.771 1.00 44.48  ? 714  SER A N   1 
ATOM   4704 C CA  . SER A 1 755  ? 111.737 123.409 116.862 1.00 44.48  ? 714  SER A CA  1 
ATOM   4705 C C   . SER A 1 755  ? 111.590 122.988 118.316 1.00 44.48  ? 714  SER A C   1 
ATOM   4706 O O   . SER A 1 755  ? 110.564 122.415 118.707 1.00 44.48  ? 714  SER A O   1 
ATOM   4707 C CB  . SER A 1 755  ? 112.868 122.640 116.183 1.00 44.48  ? 714  SER A CB  1 
ATOM   4708 O OG  . SER A 1 755  ? 113.044 123.067 114.844 1.00 44.48  ? 714  SER A OG  1 
ATOM   4709 N N   . ALA A 1 756  ? 112.564 123.359 119.153 1.00 42.94  ? 715  ALA A N   1 
ATOM   4710 C CA  . ALA A 1 756  ? 112.481 123.005 120.563 1.00 42.94  ? 715  ALA A CA  1 
ATOM   4711 C C   . ALA A 1 756  ? 111.220 123.577 121.178 1.00 42.94  ? 715  ALA A C   1 
ATOM   4712 O O   . ALA A 1 756  ? 110.479 122.866 121.870 1.00 42.94  ? 715  ALA A O   1 
ATOM   4713 C CB  . ALA A 1 756  ? 113.715 123.503 121.310 1.00 42.94  ? 715  ALA A CB  1 
ATOM   4714 N N   . PHE A 1 757  ? 110.923 124.840 120.875 1.00 43.20  ? 716  PHE A N   1 
ATOM   4715 C CA  . PHE A 1 757  ? 109.715 125.452 121.404 1.00 43.20  ? 716  PHE A CA  1 
ATOM   4716 C C   . PHE A 1 757  ? 108.502 124.606 121.059 1.00 43.20  ? 716  PHE A C   1 
ATOM   4717 O O   . PHE A 1 757  ? 107.698 124.270 121.936 1.00 43.20  ? 716  PHE A O   1 
ATOM   4718 C CB  . PHE A 1 757  ? 109.569 126.870 120.860 1.00 43.20  ? 716  PHE A CB  1 
ATOM   4719 C CG  . PHE A 1 757  ? 108.185 127.418 120.976 1.00 43.20  ? 716  PHE A CG  1 
ATOM   4720 C CD1 . PHE A 1 757  ? 107.725 127.911 122.180 1.00 43.20  ? 716  PHE A CD1 1 
ATOM   4721 C CD2 . PHE A 1 757  ? 107.344 127.446 119.879 1.00 43.20  ? 716  PHE A CD2 1 
ATOM   4722 C CE1 . PHE A 1 757  ? 106.451 128.415 122.291 1.00 43.20  ? 716  PHE A CE1 1 
ATOM   4723 C CE2 . PHE A 1 757  ? 106.070 127.951 119.982 1.00 43.20  ? 716  PHE A CE2 1 
ATOM   4724 C CZ  . PHE A 1 757  ? 105.622 128.438 121.190 1.00 43.20  ? 716  PHE A CZ  1 
ATOM   4725 N N   . PHE A 1 758  ? 108.401 124.185 119.794 1.00 43.58  ? 717  PHE A N   1 
ATOM   4726 C CA  . PHE A 1 758  ? 107.271 123.357 119.396 1.00 43.58  ? 717  PHE A CA  1 
ATOM   4727 C C   . PHE A 1 758  ? 107.163 122.140 120.296 1.00 43.58  ? 717  PHE A C   1 
ATOM   4728 O O   . PHE A 1 758  ? 106.110 121.899 120.901 1.00 43.58  ? 717  PHE A O   1 
ATOM   4729 C CB  . PHE A 1 758  ? 107.415 122.935 117.937 1.00 43.58  ? 717  PHE A CB  1 
ATOM   4730 C CG  . PHE A 1 758  ? 106.354 121.984 117.472 1.00 43.58  ? 717  PHE A CG  1 
ATOM   4731 C CD1 . PHE A 1 758  ? 105.029 122.372 117.431 1.00 43.58  ? 717  PHE A CD1 1 
ATOM   4732 C CD2 . PHE A 1 758  ? 106.681 120.702 117.073 1.00 43.58  ? 717  PHE A CD2 1 
ATOM   4733 C CE1 . PHE A 1 758  ? 104.052 121.502 116.999 1.00 43.58  ? 717  PHE A CE1 1 
ATOM   4734 C CE2 . PHE A 1 758  ? 105.708 119.827 116.642 1.00 43.58  ? 717  PHE A CE2 1 
ATOM   4735 C CZ  . PHE A 1 758  ? 104.393 120.227 116.605 1.00 43.58  ? 717  PHE A CZ  1 
ATOM   4736 N N   . ALA A 1 759  ? 108.274 121.419 120.469 1.00 42.67  ? 718  ALA A N   1 
ATOM   4737 C CA  . ALA A 1 759  ? 108.264 120.250 121.337 1.00 42.67  ? 718  ALA A CA  1 
ATOM   4738 C C   . ALA A 1 759  ? 107.709 120.610 122.703 1.00 42.67  ? 718  ALA A C   1 
ATOM   4739 O O   . ALA A 1 759  ? 106.742 119.996 123.175 1.00 42.67  ? 718  ALA A O   1 
ATOM   4740 C CB  . ALA A 1 759  ? 109.674 119.682 121.463 1.00 42.67  ? 718  ALA A CB  1 
ATOM   4741 N N   . TYR A 1 760  ? 108.249 121.672 123.308 1.00 40.81  ? 719  TYR A N   1 
ATOM   4742 C CA  . TYR A 1 760  ? 107.815 122.041 124.646 1.00 40.81  ? 719  TYR A CA  1 
ATOM   4743 C C   . TYR A 1 760  ? 106.312 122.241 124.691 1.00 40.81  ? 719  TYR A C   1 
ATOM   4744 O O   . TYR A 1 760  ? 105.641 121.715 125.587 1.00 40.81  ? 719  TYR A O   1 
ATOM   4745 C CB  . TYR A 1 760  ? 108.525 123.307 125.112 1.00 40.81  ? 719  TYR A CB  1 
ATOM   4746 C CG  . TYR A 1 760  ? 108.190 123.658 126.537 1.00 40.81  ? 719  TYR A CG  1 
ATOM   4747 C CD1 . TYR A 1 760  ? 108.618 122.863 127.585 1.00 40.81  ? 719  TYR A CD1 1 
ATOM   4748 C CD2 . TYR A 1 760  ? 107.411 124.764 126.831 1.00 40.81  ? 719  TYR A CD2 1 
ATOM   4749 C CE1 . TYR A 1 760  ? 108.306 123.174 128.885 1.00 40.81  ? 719  TYR A CE1 1 
ATOM   4750 C CE2 . TYR A 1 760  ? 107.091 125.082 128.129 1.00 40.81  ? 719  TYR A CE2 1 
ATOM   4751 C CZ  . TYR A 1 760  ? 107.540 124.283 129.152 1.00 40.81  ? 719  TYR A CZ  1 
ATOM   4752 O OH  . TYR A 1 760  ? 107.224 124.596 130.451 1.00 40.81  ? 719  TYR A OH  1 
ATOM   4753 N N   . VAL A 1 761  ? 105.760 122.940 123.698 1.00 41.12  ? 720  VAL A N   1 
ATOM   4754 C CA  . VAL A 1 761  ? 104.333 123.227 123.729 1.00 41.12  ? 720  VAL A CA  1 
ATOM   4755 C C   . VAL A 1 761  ? 103.548 121.929 123.805 1.00 41.12  ? 720  VAL A C   1 
ATOM   4756 O O   . VAL A 1 761  ? 102.688 121.759 124.679 1.00 41.12  ? 720  VAL A O   1 
ATOM   4757 C CB  . VAL A 1 761  ? 103.919 124.074 122.517 1.00 41.12  ? 720  VAL A CB  1 
ATOM   4758 C CG1 . VAL A 1 761  ? 102.419 124.024 122.335 1.00 41.12  ? 720  VAL A CG1 1 
ATOM   4759 C CG2 . VAL A 1 761  ? 104.373 125.498 122.711 1.00 41.12  ? 720  VAL A CG2 1 
ATOM   4760 N N   . LEU A 1 762  ? 103.898 120.960 122.952 1.00 42.52  ? 721  LEU A N   1 
ATOM   4761 C CA  . LEU A 1 762  ? 103.220 119.671 123.012 1.00 42.52  ? 721  LEU A CA  1 
ATOM   4762 C C   . LEU A 1 762  ? 103.279 119.117 124.424 1.00 42.52  ? 721  LEU A C   1 
ATOM   4763 O O   . LEU A 1 762  ? 102.239 118.863 125.047 1.00 42.52  ? 721  LEU A O   1 
ATOM   4764 C CB  . LEU A 1 762  ? 103.845 118.692 122.022 1.00 42.52  ? 721  LEU A CB  1 
ATOM   4765 C CG  . LEU A 1 762  ? 103.625 118.960 120.536 1.00 42.52  ? 721  LEU A CG  1 
ATOM   4766 C CD1 . LEU A 1 762  ? 104.211 117.832 119.716 1.00 42.52  ? 721  LEU A CD1 1 
ATOM   4767 C CD2 . LEU A 1 762  ? 102.150 119.113 120.242 1.00 42.52  ? 721  LEU A CD2 1 
ATOM   4768 N N   . SER A 1 763  ? 104.489 119.044 124.984 1.00 45.77  ? 722  SER A N   1 
ATOM   4769 C CA  . SER A 1 763  ? 104.646 118.554 126.344 1.00 45.77  ? 722  SER A CA  1 
ATOM   4770 C C   . SER A 1 763  ? 103.724 119.311 127.280 1.00 45.77  ? 722  SER A C   1 
ATOM   4771 O O   . SER A 1 763  ? 102.882 118.713 127.960 1.00 45.77  ? 722  SER A O   1 
ATOM   4772 C CB  . SER A 1 763  ? 106.096 118.717 126.791 1.00 45.77  ? 722  SER A CB  1 
ATOM   4773 O OG  . SER A 1 763  ? 106.987 118.212 125.821 1.00 45.77  ? 722  SER A OG  1 
ATOM   4774 N N   . ALA A 1 764  ? 103.798 120.643 127.238 1.00 47.36  ? 723  ALA A N   1 
ATOM   4775 C CA  . ALA A 1 764  ? 103.000 121.446 128.148 1.00 47.36  ? 723  ALA A CA  1 
ATOM   4776 C C   . ALA A 1 764  ? 101.532 121.097 128.009 1.00 47.36  ? 723  ALA A C   1 
ATOM   4777 O O   . ALA A 1 764  ? 100.863 120.781 129.000 1.00 47.36  ? 723  ALA A O   1 
ATOM   4778 C CB  . ALA A 1 764  ? 103.237 122.929 127.882 1.00 47.36  ? 723  ALA A CB  1 
ATOM   4779 N N   . VAL A 1 765  ? 101.038 121.048 126.771 1.00 44.77  ? 724  VAL A N   1 
ATOM   4780 C CA  . VAL A 1 765  ? 99.617  120.793 126.582 1.00 44.77  ? 724  VAL A CA  1 
ATOM   4781 C C   . VAL A 1 765  ? 99.263  119.419 127.124 1.00 44.77  ? 724  VAL A C   1 
ATOM   4782 O O   . VAL A 1 765  ? 98.266  119.258 127.838 1.00 44.77  ? 724  VAL A O   1 
ATOM   4783 C CB  . VAL A 1 765  ? 99.228  120.946 125.104 1.00 44.77  ? 724  VAL A CB  1 
ATOM   4784 C CG1 . VAL A 1 765  ? 97.823  120.447 124.887 1.00 44.77  ? 724  VAL A CG1 1 
ATOM   4785 C CG2 . VAL A 1 765  ? 99.334  122.396 124.692 1.00 44.77  ? 724  VAL A CG2 1 
ATOM   4786 N N   . LEU A 1 766  ? 100.105 118.422 126.852 1.00 42.96  ? 725  LEU A N   1 
ATOM   4787 C CA  . LEU A 1 766  ? 99.843  117.096 127.396 1.00 42.96  ? 725  LEU A CA  1 
ATOM   4788 C C   . LEU A 1 766  ? 99.831  117.145 128.915 1.00 42.96  ? 725  LEU A C   1 
ATOM   4789 O O   . LEU A 1 766  ? 98.919  116.619 129.560 1.00 42.96  ? 725  LEU A O   1 
ATOM   4790 C CB  . LEU A 1 766  ? 100.886 116.103 126.890 1.00 42.96  ? 725  LEU A CB  1 
ATOM   4791 C CG  . LEU A 1 766  ? 100.823 114.696 127.478 1.00 42.96  ? 725  LEU A CG  1 
ATOM   4792 C CD1 . LEU A 1 766  ? 99.556  113.999 127.036 1.00 42.96  ? 725  LEU A CD1 1 
ATOM   4793 C CD2 . LEU A 1 766  ? 102.042 113.899 127.065 1.00 42.96  ? 725  LEU A CD2 1 
ATOM   4794 N N   . SER A 1 767  ? 100.808 117.841 129.499 1.00 42.14  ? 726  SER A N   1 
ATOM   4795 C CA  . SER A 1 767  ? 100.864 117.955 130.949 1.00 42.14  ? 726  SER A CA  1 
ATOM   4796 C C   . SER A 1 767  ? 99.652  118.699 131.482 1.00 42.14  ? 726  SER A C   1 
ATOM   4797 O O   . SER A 1 767  ? 99.232  118.485 132.623 1.00 42.14  ? 726  SER A O   1 
ATOM   4798 C CB  . SER A 1 767  ? 102.151 118.659 131.361 1.00 42.14  ? 726  SER A CB  1 
ATOM   4799 O OG  . SER A 1 767  ? 102.209 118.812 132.761 1.00 42.14  ? 726  SER A OG  1 
ATOM   4800 N N   . VAL A 1 768  ? 99.072  119.576 130.663 1.00 42.14  ? 727  VAL A N   1 
ATOM   4801 C CA  . VAL A 1 768  ? 97.907  120.335 131.099 1.00 42.14  ? 727  VAL A CA  1 
ATOM   4802 C C   . VAL A 1 768  ? 96.651  119.484 130.972 1.00 42.14  ? 727  VAL A C   1 
ATOM   4803 O O   . VAL A 1 768  ? 95.659  119.701 131.678 1.00 42.14  ? 727  VAL A O   1 
ATOM   4804 C CB  . VAL A 1 768  ? 97.818  121.647 130.298 1.00 42.14  ? 727  VAL A CB  1 
ATOM   4805 C CG1 . VAL A 1 768  ? 96.486  122.307 130.468 1.00 42.14  ? 727  VAL A CG1 1 
ATOM   4806 C CG2 . VAL A 1 768  ? 98.911  122.597 130.740 1.00 42.14  ? 727  VAL A CG2 1 
ATOM   4807 N N   . TYR A 1 769  ? 96.687  118.474 130.099 1.00 41.47  ? 728  TYR A N   1 
ATOM   4808 C CA  . TYR A 1 769  ? 95.517  117.625 129.902 1.00 41.47  ? 728  TYR A CA  1 
ATOM   4809 C C   . TYR A 1 769  ? 95.148  116.881 131.177 1.00 41.47  ? 728  TYR A C   1 
ATOM   4810 O O   . TYR A 1 769  ? 93.966  116.693 131.482 1.00 41.47  ? 728  TYR A O   1 
ATOM   4811 C CB  . TYR A 1 769  ? 95.771  116.641 128.762 1.00 41.47  ? 728  TYR A CB  1 
ATOM   4812 C CG  . TYR A 1 769  ? 95.555  117.215 127.384 1.00 41.47  ? 728  TYR A CG  1 
ATOM   4813 C CD1 . TYR A 1 769  ? 94.833  118.379 127.204 1.00 41.47  ? 728  TYR A CD1 1 
ATOM   4814 C CD2 . TYR A 1 769  ? 96.059  116.579 126.261 1.00 41.47  ? 728  TYR A CD2 1 
ATOM   4815 C CE1 . TYR A 1 769  ? 94.629  118.898 125.950 1.00 41.47  ? 728  TYR A CE1 1 
ATOM   4816 C CE2 . TYR A 1 769  ? 95.856  117.091 125.003 1.00 41.47  ? 728  TYR A CE2 1 
ATOM   4817 C CZ  . TYR A 1 769  ? 95.139  118.249 124.853 1.00 41.47  ? 728  TYR A CZ  1 
ATOM   4818 O OH  . TYR A 1 769  ? 94.937  118.766 123.599 1.00 41.47  ? 728  TYR A OH  1 
ATOM   4819 N N   . TYR A 1 770  ? 96.150  116.442 131.931 1.00 44.35  ? 729  TYR A N   1 
ATOM   4820 C CA  . TYR A 1 770  ? 95.918  115.683 133.158 1.00 44.35  ? 729  TYR A CA  1 
ATOM   4821 C C   . TYR A 1 770  ? 95.941  116.610 134.373 1.00 44.35  ? 729  TYR A C   1 
ATOM   4822 O O   . TYR A 1 770  ? 96.731  116.461 135.305 1.00 44.35  ? 729  TYR A O   1 
ATOM   4823 C CB  . TYR A 1 770  ? 96.940  114.563 133.279 1.00 44.35  ? 729  TYR A CB  1 
ATOM   4824 C CG  . TYR A 1 770  ? 96.709  113.480 132.262 1.00 44.35  ? 729  TYR A CG  1 
ATOM   4825 C CD1 . TYR A 1 770  ? 95.758  112.497 132.474 1.00 44.35  ? 729  TYR A CD1 1 
ATOM   4826 C CD2 . TYR A 1 770  ? 97.422  113.456 131.077 1.00 44.35  ? 729  TYR A CD2 1 
ATOM   4827 C CE1 . TYR A 1 770  ? 95.533  111.515 131.544 1.00 44.35  ? 729  TYR A CE1 1 
ATOM   4828 C CE2 . TYR A 1 770  ? 97.205  112.477 130.140 1.00 44.35  ? 729  TYR A CE2 1 
ATOM   4829 C CZ  . TYR A 1 770  ? 96.259  111.509 130.378 1.00 44.35  ? 729  TYR A CZ  1 
ATOM   4830 O OH  . TYR A 1 770  ? 96.036  110.527 129.443 1.00 44.35  ? 729  TYR A OH  1 
ATOM   4831 N N   . ASN A 1 771  ? 95.038  117.587 134.342 1.00 48.81  ? 730  ASN A N   1 
ATOM   4832 C CA  . ASN A 1 771  ? 94.901  118.574 135.399 1.00 48.81  ? 730  ASN A CA  1 
ATOM   4833 C C   . ASN A 1 771  ? 93.429  118.663 135.784 1.00 48.81  ? 730  ASN A C   1 
ATOM   4834 O O   . ASN A 1 771  ? 92.587  118.992 134.932 1.00 48.81  ? 730  ASN A O   1 
ATOM   4835 C CB  . ASN A 1 771  ? 95.426  119.939 134.943 1.00 48.81  ? 730  ASN A CB  1 
ATOM   4836 C CG  . ASN A 1 771  ? 95.542  120.925 136.077 1.00 48.81  ? 730  ASN A CG  1 
ATOM   4837 O OD1 . ASN A 1 771  ? 94.541  121.362 136.639 1.00 48.81  ? 730  ASN A OD1 1 
ATOM   4838 N ND2 . ASN A 1 771  ? 96.771  121.282 136.425 1.00 48.81  ? 730  ASN A ND2 1 
ATOM   4839 N N   . PRO A 1 772  ? 93.076  118.366 137.037 1.00 52.24  ? 731  PRO A N   1 
ATOM   4840 C CA  . PRO A 1 772  ? 91.654  118.391 137.419 1.00 52.24  ? 731  PRO A CA  1 
ATOM   4841 C C   . PRO A 1 772  ? 90.999  119.753 137.265 1.00 52.24  ? 731  PRO A C   1 
ATOM   4842 O O   . PRO A 1 772  ? 89.807  119.825 136.941 1.00 52.24  ? 731  PRO A O   1 
ATOM   4843 C CB  . PRO A 1 772  ? 91.680  117.933 138.885 1.00 52.24  ? 731  PRO A CB  1 
ATOM   4844 C CG  . PRO A 1 772  ? 93.078  118.178 139.343 1.00 52.24  ? 731  PRO A CG  1 
ATOM   4845 C CD  . PRO A 1 772  ? 93.945  117.956 138.152 1.00 52.24  ? 731  PRO A CD  1 
ATOM   4846 N N   . ASP A 1 773  ? 91.739  120.836 137.483 1.00 57.37  ? 732  ASP A N   1 
ATOM   4847 C CA  . ASP A 1 773  ? 91.190  122.188 137.391 1.00 57.37  ? 732  ASP A CA  1 
ATOM   4848 C C   . ASP A 1 773  ? 90.946  122.513 135.923 1.00 57.37  ? 732  ASP A C   1 
ATOM   4849 O O   . ASP A 1 773  ? 91.887  122.693 135.150 1.00 57.37  ? 732  ASP A O   1 
ATOM   4850 C CB  . ASP A 1 773  ? 92.138  123.192 138.032 1.00 57.37  ? 732  ASP A CB  1 
ATOM   4851 C CG  . ASP A 1 773  ? 91.513  124.560 138.198 1.00 57.37  ? 732  ASP A CG  1 
ATOM   4852 O OD1 . ASP A 1 773  ? 90.324  124.720 137.851 1.00 57.37  ? 732  ASP A OD1 1 
ATOM   4853 O OD2 . ASP A 1 773  ? 92.211  125.478 138.673 1.00 57.37  ? 732  ASP A OD2 1 
ATOM   4854 N N   . HIS A 1 774  ? 89.672  122.594 135.533 1.00 56.07  ? 733  HIS A N   1 
ATOM   4855 C CA  . HIS A 1 774  ? 89.351  122.782 134.122 1.00 56.07  ? 733  HIS A CA  1 
ATOM   4856 C C   . HIS A 1 774  ? 89.619  124.210 133.662 1.00 56.07  ? 733  HIS A C   1 
ATOM   4857 O O   . HIS A 1 774  ? 90.120  124.420 132.554 1.00 56.07  ? 733  HIS A O   1 
ATOM   4858 C CB  . HIS A 1 774  ? 87.901  122.394 133.849 1.00 56.07  ? 733  HIS A CB  1 
ATOM   4859 C CG  . HIS A 1 774  ? 87.664  120.917 133.852 1.00 56.07  ? 733  HIS A CG  1 
ATOM   4860 N ND1 . HIS A 1 774  ? 88.396  120.047 133.074 1.00 56.07  ? 733  HIS A ND1 1 
ATOM   4861 C CD2 . HIS A 1 774  ? 86.766  120.158 134.521 1.00 56.07  ? 733  HIS A CD2 1 
ATOM   4862 C CE1 . HIS A 1 774  ? 87.968  118.814 133.273 1.00 56.07  ? 733  HIS A CE1 1 
ATOM   4863 N NE2 . HIS A 1 774  ? 86.979  118.854 134.145 1.00 56.07  ? 733  HIS A NE2 1 
ATOM   4864 N N   . GLU A 1 775  ? 89.277  125.206 134.482 1.00 60.05  ? 734  GLU A N   1 
ATOM   4865 C CA  . GLU A 1 775  ? 89.466  126.595 134.069 1.00 60.05  ? 734  GLU A CA  1 
ATOM   4866 C C   . GLU A 1 775  ? 90.944  126.917 133.889 1.00 60.05  ? 734  GLU A C   1 
ATOM   4867 O O   . GLU A 1 775  ? 91.336  127.606 132.936 1.00 60.05  ? 734  GLU A O   1 
ATOM   4868 C CB  . GLU A 1 775  ? 88.828  127.535 135.089 1.00 60.05  ? 734  GLU A CB  1 
ATOM   4869 C CG  . GLU A 1 775  ? 87.350  127.280 135.318 1.00 60.05  ? 734  GLU A CG  1 
ATOM   4870 C CD  . GLU A 1 775  ? 86.560  127.234 134.025 1.00 60.05  ? 734  GLU A CD  1 
ATOM   4871 O OE1 . GLU A 1 775  ? 86.547  128.250 133.300 1.00 60.05  ? 734  GLU A OE1 1 
ATOM   4872 O OE2 . GLU A 1 775  ? 85.956  126.181 133.734 1.00 60.05  ? 734  GLU A OE2 1 
ATOM   4873 N N   . TYR A 1 776  ? 91.782  126.424 134.801 1.00 53.82  ? 735  TYR A N   1 
ATOM   4874 C CA  . TYR A 1 776  ? 93.220  126.613 134.663 1.00 53.82  ? 735  TYR A CA  1 
ATOM   4875 C C   . TYR A 1 776  ? 93.731  125.975 133.382 1.00 53.82  ? 735  TYR A C   1 
ATOM   4876 O O   . TYR A 1 776  ? 94.573  126.550 132.683 1.00 53.82  ? 735  TYR A O   1 
ATOM   4877 C CB  . TYR A 1 776  ? 93.938  126.029 135.875 1.00 53.82  ? 735  TYR A CB  1 
ATOM   4878 C CG  . TYR A 1 776  ? 95.440  126.127 135.805 1.00 53.82  ? 735  TYR A CG  1 
ATOM   4879 C CD1 . TYR A 1 776  ? 96.076  127.356 135.837 1.00 53.82  ? 735  TYR A CD1 1 
ATOM   4880 C CD2 . TYR A 1 776  ? 96.222  124.988 135.706 1.00 53.82  ? 735  TYR A CD2 1 
ATOM   4881 C CE1 . TYR A 1 776  ? 97.448  127.448 135.779 1.00 53.82  ? 735  TYR A CE1 1 
ATOM   4882 C CE2 . TYR A 1 776  ? 97.594  125.070 135.645 1.00 53.82  ? 735  TYR A CE2 1 
ATOM   4883 C CZ  . TYR A 1 776  ? 98.202  126.301 135.681 1.00 53.82  ? 735  TYR A CZ  1 
ATOM   4884 O OH  . TYR A 1 776  ? 99.572  126.385 135.620 1.00 53.82  ? 735  TYR A OH  1 
ATOM   4885 N N   . MET A 1 777  ? 93.228  124.784 133.057 1.00 50.95  ? 736  MET A N   1 
ATOM   4886 C CA  . MET A 1 777  ? 93.659  124.115 131.837 1.00 50.95  ? 736  MET A CA  1 
ATOM   4887 C C   . MET A 1 777  ? 93.199  124.882 130.603 1.00 50.95  ? 736  MET A C   1 
ATOM   4888 O O   . MET A 1 777  ? 93.933  124.979 129.616 1.00 50.95  ? 736  MET A O   1 
ATOM   4889 C CB  . MET A 1 777  ? 93.159  122.669 131.823 1.00 50.95  ? 736  MET A CB  1 
ATOM   4890 C CG  . MET A 1 777  ? 93.005  122.056 130.444 1.00 50.95  ? 736  MET A CG  1 
ATOM   4891 S SD  . MET A 1 777  ? 92.525  120.324 130.521 1.00 50.95  ? 736  MET A SD  1 
ATOM   4892 C CE  . MET A 1 777  ? 90.765  120.443 130.292 1.00 50.95  ? 736  MET A CE  1 
ATOM   4893 N N   . ILE A 1 778  ? 91.997  125.461 130.651 1.00 53.36  ? 737  ILE A N   1 
ATOM   4894 C CA  . ILE A 1 778  ? 91.528  126.288 129.541 1.00 53.36  ? 737  ILE A CA  1 
ATOM   4895 C C   . ILE A 1 778  ? 92.462  127.469 129.333 1.00 53.36  ? 737  ILE A C   1 
ATOM   4896 O O   . ILE A 1 778  ? 92.873  127.769 128.205 1.00 53.36  ? 737  ILE A O   1 
ATOM   4897 C CB  . ILE A 1 778  ? 90.087  126.766 129.786 1.00 53.36  ? 737  ILE A CB  1 
ATOM   4898 C CG1 . ILE A 1 778  ? 89.118  125.592 129.830 1.00 53.36  ? 737  ILE A CG1 1 
ATOM   4899 C CG2 . ILE A 1 778  ? 89.670  127.755 128.714 1.00 53.36  ? 737  ILE A CG2 1 
ATOM   4900 C CD1 . ILE A 1 778  ? 87.718  125.988 130.228 1.00 53.36  ? 737  ILE A CD1 1 
ATOM   4901 N N   . LYS A 1 779  ? 92.809  128.160 130.418 1.00 52.52  ? 738  LYS A N   1 
ATOM   4902 C CA  . LYS A 1 779  ? 93.678  129.326 130.294 1.00 52.52  ? 738  LYS A CA  1 
ATOM   4903 C C   . LYS A 1 779  ? 95.047  128.936 129.749 1.00 52.52  ? 738  LYS A C   1 
ATOM   4904 O O   . LYS A 1 779  ? 95.576  129.590 128.842 1.00 52.52  ? 738  LYS A O   1 
ATOM   4905 C CB  . LYS A 1 779  ? 93.811  130.029 131.643 1.00 52.52  ? 738  LYS A CB  1 
ATOM   4906 C CG  . LYS A 1 779  ? 92.529  130.690 132.120 1.00 52.52  ? 738  LYS A CG  1 
ATOM   4907 C CD  . LYS A 1 779  ? 92.410  130.656 133.633 1.00 52.52  ? 738  LYS A CD  1 
ATOM   4908 C CE  . LYS A 1 779  ? 93.716  131.040 134.307 1.00 52.52  ? 738  LYS A CE  1 
ATOM   4909 N NZ  . LYS A 1 779  ? 93.624  130.911 135.787 1.00 52.52  ? 738  LYS A NZ  1 
ATOM   4910 N N   . GLN A 1 780  ? 95.626  127.856 130.277 1.00 47.56  ? 739  GLN A N   1 
ATOM   4911 C CA  . GLN A 1 780  ? 96.943  127.427 129.818 1.00 47.56  ? 739  GLN A CA  1 
ATOM   4912 C C   . GLN A 1 780  ? 96.912  127.020 128.350 1.00 47.56  ? 739  GLN A C   1 
ATOM   4913 O O   . GLN A 1 780  ? 97.815  127.365 127.579 1.00 47.56  ? 739  GLN A O   1 
ATOM   4914 C CB  . GLN A 1 780  ? 97.448  126.278 130.686 1.00 47.56  ? 739  GLN A CB  1 
ATOM   4915 C CG  . GLN A 1 780  ? 97.849  126.697 132.082 1.00 47.56  ? 739  GLN A CG  1 
ATOM   4916 C CD  . GLN A 1 780  ? 98.974  127.706 132.084 1.00 47.56  ? 739  GLN A CD  1 
ATOM   4917 O OE1 . GLN A 1 780  ? 98.804  128.841 132.521 1.00 47.56  ? 739  GLN A OE1 1 
ATOM   4918 N NE2 . GLN A 1 780  ? 100.135 127.293 131.601 1.00 47.56  ? 739  GLN A NE2 1 
ATOM   4919 N N   . ILE A 1 781  ? 95.875  126.287 127.943 1.00 46.57  ? 740  ILE A N   1 
ATOM   4920 C CA  . ILE A 1 781  ? 95.794  125.815 126.565 1.00 46.57  ? 740  ILE A CA  1 
ATOM   4921 C C   . ILE A 1 781  ? 95.605  126.986 125.614 1.00 46.57  ? 740  ILE A C   1 
ATOM   4922 O O   . ILE A 1 781  ? 96.202  127.028 124.534 1.00 46.57  ? 740  ILE A O   1 
ATOM   4923 C CB  . ILE A 1 781  ? 94.674  124.771 126.421 1.00 46.57  ? 740  ILE A CB  1 
ATOM   4924 C CG1 . ILE A 1 781  ? 95.124  123.437 127.008 1.00 46.57  ? 740  ILE A CG1 1 
ATOM   4925 C CG2 . ILE A 1 781  ? 94.289  124.590 124.967 1.00 46.57  ? 740  ILE A CG2 1 
ATOM   4926 C CD1 . ILE A 1 781  ? 94.126  122.331 126.825 1.00 46.57  ? 740  ILE A CD1 1 
ATOM   4927 N N   . ASP A 1 782  ? 94.772  127.956 125.995 1.00 49.76  ? 741  ASP A N   1 
ATOM   4928 C CA  . ASP A 1 782  ? 94.606  129.139 125.158 1.00 49.76  ? 741  ASP A CA  1 
ATOM   4929 C C   . ASP A 1 782  ? 95.917  129.899 125.027 1.00 49.76  ? 741  ASP A C   1 
ATOM   4930 O O   . ASP A 1 782  ? 96.279  130.349 123.934 1.00 49.76  ? 741  ASP A O   1 
ATOM   4931 C CB  . ASP A 1 782  ? 93.515  130.047 125.721 1.00 49.76  ? 741  ASP A CB  1 
ATOM   4932 C CG  . ASP A 1 782  ? 92.139  129.436 125.613 1.00 49.76  ? 741  ASP A CG  1 
ATOM   4933 O OD1 . ASP A 1 782  ? 92.036  128.281 125.149 1.00 49.76  ? 741  ASP A OD1 1 
ATOM   4934 O OD2 . ASP A 1 782  ? 91.157  130.113 125.980 1.00 49.76  ? 741  ASP A OD2 1 
ATOM   4935 N N   . LYS A 1 783  ? 96.649  130.043 126.132 1.00 47.16  ? 742  LYS A N   1 
ATOM   4936 C CA  . LYS A 1 783  ? 97.931  130.736 126.078 1.00 47.16  ? 742  LYS A CA  1 
ATOM   4937 C C   . LYS A 1 783  ? 98.897  130.027 125.139 1.00 47.16  ? 742  LYS A C   1 
ATOM   4938 O O   . LYS A 1 783  ? 99.538  130.662 124.293 1.00 47.16  ? 742  LYS A O   1 
ATOM   4939 C CB  . LYS A 1 783  ? 98.521  130.844 127.481 1.00 47.16  ? 742  LYS A CB  1 
ATOM   4940 C CG  . LYS A 1 783  ? 100.033 130.921 127.519 1.00 47.16  ? 742  LYS A CG  1 
ATOM   4941 C CD  . LYS A 1 783  ? 100.549 130.630 128.915 1.00 47.16  ? 742  LYS A CD  1 
ATOM   4942 C CE  . LYS A 1 783  ? 102.064 130.627 128.957 1.00 47.16  ? 742  LYS A CE  1 
ATOM   4943 N NZ  . LYS A 1 783  ? 102.571 130.273 130.309 1.00 47.16  ? 742  LYS A NZ  1 
ATOM   4944 N N   . TYR A 1 784  ? 98.995  128.702 125.257 1.00 44.40  ? 743  TYR A N   1 
ATOM   4945 C CA  . TYR A 1 784  ? 99.926  127.956 124.415 1.00 44.40  ? 743  TYR A CA  1 
ATOM   4946 C C   . TYR A 1 784  ? 99.512  127.989 122.949 1.00 44.40  ? 743  TYR A C   1 
ATOM   4947 O O   . TYR A 1 784  ? 100.364 128.104 122.063 1.00 44.40  ? 743  TYR A O   1 
ATOM   4948 C CB  . TYR A 1 784  ? 100.047 126.517 124.909 1.00 44.40  ? 743  TYR A CB  1 
ATOM   4949 C CG  . TYR A 1 784  ? 100.829 126.398 126.189 1.00 44.40  ? 743  TYR A CG  1 
ATOM   4950 C CD1 . TYR A 1 784  ? 102.079 126.982 126.311 1.00 44.40  ? 743  TYR A CD1 1 
ATOM   4951 C CD2 . TYR A 1 784  ? 100.322 125.705 127.274 1.00 44.40  ? 743  TYR A CD2 1 
ATOM   4952 C CE1 . TYR A 1 784  ? 102.801 126.880 127.478 1.00 44.40  ? 743  TYR A CE1 1 
ATOM   4953 C CE2 . TYR A 1 784  ? 101.034 125.599 128.446 1.00 44.40  ? 743  TYR A CE2 1 
ATOM   4954 C CZ  . TYR A 1 784  ? 102.275 126.187 128.543 1.00 44.40  ? 743  TYR A CZ  1 
ATOM   4955 O OH  . TYR A 1 784  ? 102.994 126.083 129.710 1.00 44.40  ? 743  TYR A OH  1 
ATOM   4956 N N   . CYS A 1 785  ? 98.213  127.890 122.669 1.00 47.08  ? 744  CYS A N   1 
ATOM   4957 C CA  . CYS A 1 785  ? 97.756  127.930 121.285 1.00 47.08  ? 744  CYS A CA  1 
ATOM   4958 C C   . CYS A 1 785  ? 98.017  129.293 120.657 1.00 47.08  ? 744  CYS A C   1 
ATOM   4959 O O   . CYS A 1 785  ? 98.455  129.385 119.504 1.00 47.08  ? 744  CYS A O   1 
ATOM   4960 C CB  . CYS A 1 785  ? 96.273  127.574 121.212 1.00 47.08  ? 744  CYS A CB  1 
ATOM   4961 S SG  . CYS A 1 785  ? 95.919  125.840 121.557 1.00 47.08  ? 744  CYS A SG  1 
ATOM   4962 N N   . TYR A 1 786  ? 97.754  130.369 121.401 1.00 50.13  ? 745  TYR A N   1 
ATOM   4963 C CA  . TYR A 1 786  ? 98.037  131.701 120.880 1.00 50.13  ? 745  TYR A CA  1 
ATOM   4964 C C   . TYR A 1 786  ? 99.529  131.886 120.652 1.00 50.13  ? 745  TYR A C   1 
ATOM   4965 O O   . TYR A 1 786  ? 99.948  132.474 119.649 1.00 50.13  ? 745  TYR A O   1 
ATOM   4966 C CB  . TYR A 1 786  ? 97.491  132.766 121.829 1.00 50.13  ? 745  TYR A CB  1 
ATOM   4967 C CG  . TYR A 1 786  ? 95.987  132.882 121.787 1.00 50.13  ? 745  TYR A CG  1 
ATOM   4968 C CD1 . TYR A 1 786  ? 95.295  132.706 120.597 1.00 50.13  ? 745  TYR A CD1 1 
ATOM   4969 C CD2 . TYR A 1 786  ? 95.257  133.155 122.935 1.00 50.13  ? 745  TYR A CD2 1 
ATOM   4970 C CE1 . TYR A 1 786  ? 93.920  132.805 120.550 1.00 50.13  ? 745  TYR A CE1 1 
ATOM   4971 C CE2 . TYR A 1 786  ? 93.881  133.258 122.896 1.00 50.13  ? 745  TYR A CE2 1 
ATOM   4972 C CZ  . TYR A 1 786  ? 93.219  133.080 121.701 1.00 50.13  ? 745  TYR A CZ  1 
ATOM   4973 O OH  . TYR A 1 786  ? 91.847  133.180 121.653 1.00 50.13  ? 745  TYR A OH  1 
ATOM   4974 N N   . LEU A 1 787  ? 100.352 131.373 121.568 1.00 46.01  ? 746  LEU A N   1 
ATOM   4975 C CA  . LEU A 1 787  ? 101.796 131.480 121.401 1.00 46.01  ? 746  LEU A CA  1 
ATOM   4976 C C   . LEU A 1 787  ? 102.268 130.713 120.170 1.00 46.01  ? 746  LEU A C   1 
ATOM   4977 O O   . LEU A 1 787  ? 103.136 131.184 119.427 1.00 46.01  ? 746  LEU A O   1 
ATOM   4978 C CB  . LEU A 1 787  ? 102.491 130.979 122.662 1.00 46.01  ? 746  LEU A CB  1 
ATOM   4979 C CG  . LEU A 1 787  ? 103.993 131.194 122.780 1.00 46.01  ? 746  LEU A CG  1 
ATOM   4980 C CD1 . LEU A 1 787  ? 104.303 132.675 122.734 1.00 46.01  ? 746  LEU A CD1 1 
ATOM   4981 C CD2 . LEU A 1 787  ? 104.482 130.595 124.082 1.00 46.01  ? 746  LEU A CD2 1 
ATOM   4982 N N   . LEU A 1 788  ? 101.699 129.530 119.937 1.00 45.72  ? 747  LEU A N   1 
ATOM   4983 C CA  . LEU A 1 788  ? 102.074 128.728 118.777 1.00 45.72  ? 747  LEU A CA  1 
ATOM   4984 C C   . LEU A 1 788  ? 101.678 129.423 117.479 1.00 45.72  ? 747  LEU A C   1 
ATOM   4985 O O   . LEU A 1 788  ? 102.461 129.475 116.520 1.00 45.72  ? 747  LEU A O   1 
ATOM   4986 C CB  . LEU A 1 788  ? 101.418 127.351 118.880 1.00 45.72  ? 747  LEU A CB  1 
ATOM   4987 C CG  . LEU A 1 788  ? 102.036 126.172 118.142 1.00 45.72  ? 747  LEU A CG  1 
ATOM   4988 C CD1 . LEU A 1 788  ? 103.438 125.920 118.649 1.00 45.72  ? 747  LEU A CD1 1 
ATOM   4989 C CD2 . LEU A 1 788  ? 101.177 124.941 118.336 1.00 45.72  ? 747  LEU A CD2 1 
ATOM   4990 N N   . ILE A 1 789  ? 100.462 129.969 117.432 1.00 43.92  ? 748  ILE A N   1 
ATOM   4991 C CA  . ILE A 1 789  ? 100.025 130.706 116.250 1.00 43.92  ? 748  ILE A CA  1 
ATOM   4992 C C   . ILE A 1 789  ? 100.920 131.915 116.014 1.00 43.92  ? 748  ILE A C   1 
ATOM   4993 O O   . ILE A 1 789  ? 101.264 132.240 114.872 1.00 43.92  ? 748  ILE A O   1 
ATOM   4994 C CB  . ILE A 1 789  ? 98.546  131.112 116.385 1.00 43.92  ? 748  ILE A CB  1 
ATOM   4995 C CG1 . ILE A 1 789  ? 97.654  129.875 116.369 1.00 43.92  ? 748  ILE A CG1 1 
ATOM   4996 C CG2 . ILE A 1 789  ? 98.147  132.059 115.275 1.00 43.92  ? 748  ILE A CG2 1 
ATOM   4997 C CD1 . ILE A 1 789  ? 96.195  130.182 116.563 1.00 43.92  ? 748  ILE A CD1 1 
ATOM   4998 N N   . GLY A 1 790  ? 101.314 132.599 117.088 1.00 50.48  ? 749  GLY A N   1 
ATOM   4999 C CA  . GLY A 1 790  ? 102.195 133.743 116.934 1.00 50.48  ? 749  GLY A CA  1 
ATOM   5000 C C   . GLY A 1 790  ? 103.565 133.368 116.403 1.00 50.48  ? 749  GLY A C   1 
ATOM   5001 O O   . GLY A 1 790  ? 104.125 134.070 115.558 1.00 50.48  ? 749  GLY A O   1 
ATOM   5002 N N   . LEU A 1 791  ? 104.125 132.263 116.889 1.00 48.51  ? 750  LEU A N   1 
ATOM   5003 C CA  . LEU A 1 791  ? 105.472 131.872 116.494 1.00 48.51  ? 750  LEU A CA  1 
ATOM   5004 C C   . LEU A 1 791  ? 105.529 131.120 115.171 1.00 48.51  ? 750  LEU A C   1 
ATOM   5005 O O   . LEU A 1 791  ? 106.629 130.906 114.648 1.00 48.51  ? 750  LEU A O   1 
ATOM   5006 C CB  . LEU A 1 791  ? 106.119 131.025 117.590 1.00 48.51  ? 750  LEU A CB  1 
ATOM   5007 C CG  . LEU A 1 791  ? 106.502 131.804 118.849 1.00 48.51  ? 750  LEU A CG  1 
ATOM   5008 C CD1 . LEU A 1 791  ? 107.587 131.081 119.622 1.00 48.51  ? 750  LEU A CD1 1 
ATOM   5009 C CD2 . LEU A 1 791  ? 106.947 133.212 118.493 1.00 48.51  ? 750  LEU A CD2 1 
ATOM   5010 N N   . SER A 1 792  ? 104.386 130.715 114.614 1.00 49.57  ? 751  SER A N   1 
ATOM   5011 C CA  . SER A 1 792  ? 104.406 130.103 113.288 1.00 49.57  ? 751  SER A CA  1 
ATOM   5012 C C   . SER A 1 792  ? 104.969 131.064 112.247 1.00 49.57  ? 751  SER A C   1 
ATOM   5013 O O   . SER A 1 792  ? 105.754 130.670 111.371 1.00 49.57  ? 751  SER A O   1 
ATOM   5014 C CB  . SER A 1 792  ? 102.999 129.654 112.900 1.00 49.57  ? 751  SER A CB  1 
ATOM   5015 O OG  . SER A 1 792  ? 102.143 130.768 112.728 1.00 49.57  ? 751  SER A OG  1 
ATOM   5016 N N   . SER A 1 793  ? 104.573 132.337 112.323 1.00 50.27  ? 752  SER A N   1 
ATOM   5017 C CA  . SER A 1 793  ? 105.073 133.331 111.380 1.00 50.27  ? 752  SER A CA  1 
ATOM   5018 C C   . SER A 1 793  ? 106.578 133.514 111.515 1.00 50.27  ? 752  SER A C   1 
ATOM   5019 O O   . SER A 1 793  ? 107.288 133.650 110.511 1.00 50.27  ? 752  SER A O   1 
ATOM   5020 C CB  . SER A 1 793  ? 104.351 134.659 111.587 1.00 50.27  ? 752  SER A CB  1 
ATOM   5021 O OG  . SER A 1 793  ? 104.886 135.663 110.746 1.00 50.27  ? 752  SER A OG  1 
ATOM   5022 N N   . ALA A 1 794  ? 107.082 133.535 112.750 1.00 48.75  ? 753  ALA A N   1 
ATOM   5023 C CA  . ALA A 1 794  ? 108.521 133.636 112.959 1.00 48.75  ? 753  ALA A CA  1 
ATOM   5024 C C   . ALA A 1 794  ? 109.238 132.429 112.374 1.00 48.75  ? 753  ALA A C   1 
ATOM   5025 O O   . ALA A 1 794  ? 110.311 132.560 111.775 1.00 48.75  ? 753  ALA A O   1 
ATOM   5026 C CB  . ALA A 1 794  ? 108.828 133.778 114.448 1.00 48.75  ? 753  ALA A CB  1 
ATOM   5027 N N   . ALA A 1 795  ? 108.655 131.240 112.537 1.00 48.50  ? 754  ALA A N   1 
ATOM   5028 C CA  . ALA A 1 795  ? 109.242 130.045 111.937 1.00 48.50  ? 754  ALA A CA  1 
ATOM   5029 C C   . ALA A 1 795  ? 109.358 130.197 110.427 1.00 48.50  ? 754  ALA A C   1 
ATOM   5030 O O   . ALA A 1 795  ? 110.425 129.962 109.848 1.00 48.50  ? 754  ALA A O   1 
ATOM   5031 C CB  . ALA A 1 795  ? 108.411 128.815 112.292 1.00 48.50  ? 754  ALA A CB  1 
ATOM   5032 N N   . LEU A 1 796  ? 108.271 130.618 109.777 1.00 49.94  ? 755  LEU A N   1 
ATOM   5033 C CA  . LEU A 1 796  ? 108.300 130.835 108.331 1.00 49.94  ? 755  LEU A CA  1 
ATOM   5034 C C   . LEU A 1 796  ? 109.387 131.827 107.934 1.00 49.94  ? 755  LEU A C   1 
ATOM   5035 O O   . LEU A 1 796  ? 110.254 131.527 107.093 1.00 49.94  ? 755  LEU A O   1 
ATOM   5036 C CB  . LEU A 1 796  ? 106.935 131.336 107.858 1.00 49.94  ? 755  LEU A CB  1 
ATOM   5037 C CG  . LEU A 1 796  ? 106.816 131.912 106.445 1.00 49.94  ? 755  LEU A CG  1 
ATOM   5038 C CD1 . LEU A 1 796  ? 107.201 130.911 105.381 1.00 49.94  ? 755  LEU A CD1 1 
ATOM   5039 C CD2 . LEU A 1 796  ? 105.409 132.429 106.203 1.00 49.94  ? 755  LEU A CD2 1 
ATOM   5040 N N   . VAL A 1 797  ? 109.370 133.007 108.553 1.00 50.29  ? 756  VAL A N   1 
ATOM   5041 C CA  . VAL A 1 797  ? 110.266 134.082 108.143 1.00 50.29  ? 756  VAL A CA  1 
ATOM   5042 C C   . VAL A 1 797  ? 111.716 133.662 108.325 1.00 50.29  ? 756  VAL A C   1 
ATOM   5043 O O   . VAL A 1 797  ? 112.554 133.860 107.439 1.00 50.29  ? 756  VAL A O   1 
ATOM   5044 C CB  . VAL A 1 797  ? 109.950 135.370 108.920 1.00 50.29  ? 756  VAL A CB  1 
ATOM   5045 C CG1 . VAL A 1 797  ? 111.042 136.396 108.707 1.00 50.29  ? 756  VAL A CG1 1 
ATOM   5046 C CG2 . VAL A 1 797  ? 108.610 135.926 108.485 1.00 50.29  ? 756  VAL A CG2 1 
ATOM   5047 N N   . PHE A 1 798  ? 112.034 133.054 109.465 1.00 50.94  ? 757  PHE A N   1 
ATOM   5048 C CA  . PHE A 1 798  ? 113.437 132.799 109.749 1.00 50.94  ? 757  PHE A CA  1 
ATOM   5049 C C   . PHE A 1 798  ? 113.940 131.555 109.031 1.00 50.94  ? 757  PHE A C   1 
ATOM   5050 O O   . PHE A 1 798  ? 115.130 131.466 108.715 1.00 50.94  ? 757  PHE A O   1 
ATOM   5051 C CB  . PHE A 1 798  ? 113.661 132.723 111.256 1.00 50.94  ? 757  PHE A CB  1 
ATOM   5052 C CG  . PHE A 1 798  ? 113.631 134.070 111.918 1.00 50.94  ? 757  PHE A CG  1 
ATOM   5053 C CD1 . PHE A 1 798  ? 112.427 134.701 112.173 1.00 50.94  ? 757  PHE A CD1 1 
ATOM   5054 C CD2 . PHE A 1 798  ? 114.800 134.715 112.267 1.00 50.94  ? 757  PHE A CD2 1 
ATOM   5055 C CE1 . PHE A 1 798  ? 112.391 135.940 112.770 1.00 50.94  ? 757  PHE A CE1 1 
ATOM   5056 C CE2 . PHE A 1 798  ? 114.767 135.960 112.855 1.00 50.94  ? 757  PHE A CE2 1 
ATOM   5057 C CZ  . PHE A 1 798  ? 113.561 136.569 113.113 1.00 50.94  ? 757  PHE A CZ  1 
ATOM   5058 N N   . ASN A 1 799  ? 113.055 130.608 108.703 1.00 50.91  ? 758  ASN A N   1 
ATOM   5059 C CA  . ASN A 1 799  ? 113.460 129.533 107.803 1.00 50.91  ? 758  ASN A CA  1 
ATOM   5060 C C   . ASN A 1 799  ? 113.856 130.087 106.443 1.00 50.91  ? 758  ASN A C   1 
ATOM   5061 O O   . ASN A 1 799  ? 114.931 129.764 105.912 1.00 50.91  ? 758  ASN A O   1 
ATOM   5062 C CB  . ASN A 1 799  ? 112.339 128.510 107.656 1.00 50.91  ? 758  ASN A CB  1 
ATOM   5063 C CG  . ASN A 1 799  ? 112.272 127.555 108.819 1.00 50.91  ? 758  ASN A CG  1 
ATOM   5064 O OD1 . ASN A 1 799  ? 113.228 126.834 109.098 1.00 50.91  ? 758  ASN A OD1 1 
ATOM   5065 N ND2 . ASN A 1 799  ? 111.138 127.537 109.506 1.00 50.91  ? 758  ASN A ND2 1 
ATOM   5066 N N   . THR A 1 800  ? 113.003 130.942 105.866 1.00 52.27  ? 759  THR A N   1 
ATOM   5067 C CA  . THR A 1 800  ? 113.342 131.526 104.571 1.00 52.27  ? 759  THR A CA  1 
ATOM   5068 C C   . THR A 1 800  ? 114.640 132.315 104.655 1.00 52.27  ? 759  THR A C   1 
ATOM   5069 O O   . THR A 1 800  ? 115.516 132.185 103.793 1.00 52.27  ? 759  THR A O   1 
ATOM   5070 C CB  . THR A 1 800  ? 112.215 132.424 104.066 1.00 52.27  ? 759  THR A CB  1 
ATOM   5071 O OG1 . THR A 1 800  ? 112.113 133.578 104.907 1.00 52.27  ? 759  THR A OG1 1 
ATOM   5072 C CG2 . THR A 1 800  ? 110.900 131.683 104.060 1.00 52.27  ? 759  THR A CG2 1 
ATOM   5073 N N   . LEU A 1 801  ? 114.787 133.125 105.704 1.00 50.48  ? 760  LEU A N   1 
ATOM   5074 C CA  . LEU A 1 801  ? 115.978 133.955 105.849 1.00 50.48  ? 760  LEU A CA  1 
ATOM   5075 C C   . LEU A 1 801  ? 117.237 133.102 105.939 1.00 50.48  ? 760  LEU A C   1 
ATOM   5076 O O   . LEU A 1 801  ? 118.214 133.335 105.213 1.00 50.48  ? 760  LEU A O   1 
ATOM   5077 C CB  . LEU A 1 801  ? 115.834 134.836 107.088 1.00 50.48  ? 760  LEU A CB  1 
ATOM   5078 C CG  . LEU A 1 801  ? 116.840 135.964 107.293 1.00 50.48  ? 760  LEU A CG  1 
ATOM   5079 C CD1 . LEU A 1 801  ? 116.609 137.056 106.267 1.00 50.48  ? 760  LEU A CD1 1 
ATOM   5080 C CD2 . LEU A 1 801  ? 116.738 136.514 108.702 1.00 50.48  ? 760  LEU A CD2 1 
ATOM   5081 N N   . GLN A 1 802  ? 117.227 132.100 106.820 1.00 52.87  ? 761  GLN A N   1 
ATOM   5082 C CA  . GLN A 1 802  ? 118.398 131.255 107.016 1.00 52.87  ? 761  GLN A CA  1 
ATOM   5083 C C   . GLN A 1 802  ? 118.800 130.568 105.724 1.00 52.87  ? 761  GLN A C   1 
ATOM   5084 O O   . GLN A 1 802  ? 119.969 130.611 105.317 1.00 52.87  ? 761  GLN A O   1 
ATOM   5085 C CB  . GLN A 1 802  ? 118.112 130.213 108.093 1.00 52.87  ? 761  GLN A CB  1 
ATOM   5086 C CG  . GLN A 1 802  ? 119.069 129.044 108.067 1.00 52.87  ? 761  GLN A CG  1 
ATOM   5087 C CD  . GLN A 1 802  ? 118.473 127.799 108.674 1.00 52.87  ? 761  GLN A CD  1 
ATOM   5088 O OE1 . GLN A 1 802  ? 117.314 127.786 109.074 1.00 52.87  ? 761  GLN A OE1 1 
ATOM   5089 N NE2 . GLN A 1 802  ? 119.266 126.740 108.749 1.00 52.87  ? 761  GLN A NE2 1 
ATOM   5090 N N   . HIS A 1 803  ? 117.843 129.912 105.064 1.00 53.06  ? 762  HIS A N   1 
ATOM   5091 C CA  . HIS A 1 803  ? 118.201 129.145 103.876 1.00 53.06  ? 762  HIS A CA  1 
ATOM   5092 C C   . HIS A 1 803  ? 118.656 130.057 102.746 1.00 53.06  ? 762  HIS A C   1 
ATOM   5093 O O   . HIS A 1 803  ? 119.639 129.759 102.060 1.00 53.06  ? 762  HIS A O   1 
ATOM   5094 C CB  . HIS A 1 803  ? 117.038 128.259 103.448 1.00 53.06  ? 762  HIS A CB  1 
ATOM   5095 C CG  . HIS A 1 803  ? 116.861 127.061 104.323 1.00 53.06  ? 762  HIS A CG  1 
ATOM   5096 N ND1 . HIS A 1 803  ? 117.850 126.116 104.491 1.00 53.06  ? 762  HIS A ND1 1 
ATOM   5097 C CD2 . HIS A 1 803  ? 115.829 126.667 105.103 1.00 53.06  ? 762  HIS A CD2 1 
ATOM   5098 C CE1 . HIS A 1 803  ? 117.428 125.183 105.325 1.00 53.06  ? 762  HIS A CE1 1 
ATOM   5099 N NE2 . HIS A 1 803  ? 116.205 125.495 105.712 1.00 53.06  ? 762  HIS A NE2 1 
ATOM   5100 N N   . SER A 1 804  ? 117.978 131.193 102.557 1.00 54.02  ? 763  SER A N   1 
ATOM   5101 C CA  . SER A 1 804  ? 118.382 132.117 101.505 1.00 54.02  ? 763  SER A CA  1 
ATOM   5102 C C   . SER A 1 804  ? 119.806 132.608 101.720 1.00 54.02  ? 763  SER A C   1 
ATOM   5103 O O   . SER A 1 804  ? 120.622 132.607 100.790 1.00 54.02  ? 763  SER A O   1 
ATOM   5104 C CB  . SER A 1 804  ? 117.413 133.295 101.443 1.00 54.02  ? 763  SER A CB  1 
ATOM   5105 O OG  . SER A 1 804  ? 116.089 132.849 101.231 1.00 54.02  ? 763  SER A OG  1 
ATOM   5106 N N   . PHE A 1 805  ? 120.137 133.007 102.948 1.00 55.40  ? 764  PHE A N   1 
ATOM   5107 C CA  . PHE A 1 805  ? 121.449 133.607 103.161 1.00 55.40  ? 764  PHE A CA  1 
ATOM   5108 C C   . PHE A 1 805  ? 122.557 132.562 103.119 1.00 55.40  ? 764  PHE A C   1 
ATOM   5109 O O   . PHE A 1 805  ? 123.642 132.820 102.579 1.00 55.40  ? 764  PHE A O   1 
ATOM   5110 C CB  . PHE A 1 805  ? 121.462 134.384 104.474 1.00 55.40  ? 764  PHE A CB  1 
ATOM   5111 C CG  . PHE A 1 805  ? 120.824 135.739 104.369 1.00 55.40  ? 764  PHE A CG  1 
ATOM   5112 C CD1 . PHE A 1 805  ? 119.595 135.894 103.751 1.00 55.40  ? 764  PHE A CD1 1 
ATOM   5113 C CD2 . PHE A 1 805  ? 121.451 136.856 104.879 1.00 55.40  ? 764  PHE A CD2 1 
ATOM   5114 C CE1 . PHE A 1 805  ? 119.008 137.132 103.648 1.00 55.40  ? 764  PHE A CE1 1 
ATOM   5115 C CE2 . PHE A 1 805  ? 120.865 138.097 104.776 1.00 55.40  ? 764  PHE A CE2 1 
ATOM   5116 C CZ  . PHE A 1 805  ? 119.642 138.235 104.161 1.00 55.40  ? 764  PHE A CZ  1 
ATOM   5117 N N   . TRP A 1 806  ? 122.304 131.366 103.655 1.00 55.66  ? 765  TRP A N   1 
ATOM   5118 C CA  . TRP A 1 806  ? 123.312 130.316 103.559 1.00 55.66  ? 765  TRP A CA  1 
ATOM   5119 C C   . TRP A 1 806  ? 123.522 129.888 102.114 1.00 55.66  ? 765  TRP A C   1 
ATOM   5120 O O   . TRP A 1 806  ? 124.650 129.580 101.707 1.00 55.66  ? 765  TRP A O   1 
ATOM   5121 C CB  . TRP A 1 806  ? 122.920 129.130 104.431 1.00 55.66  ? 765  TRP A CB  1 
ATOM   5122 C CG  . TRP A 1 806  ? 123.247 129.355 105.862 1.00 55.66  ? 765  TRP A CG  1 
ATOM   5123 C CD1 . TRP A 1 806  ? 122.380 129.342 106.907 1.00 55.66  ? 765  TRP A CD1 1 
ATOM   5124 C CD2 . TRP A 1 806  ? 124.536 129.641 106.412 1.00 55.66  ? 765  TRP A CD2 1 
ATOM   5125 N NE1 . TRP A 1 806  ? 123.045 129.601 108.078 1.00 55.66  ? 765  TRP A NE1 1 
ATOM   5126 C CE2 . TRP A 1 806  ? 124.372 129.786 107.800 1.00 55.66  ? 765  TRP A CE2 1 
ATOM   5127 C CE3 . TRP A 1 806  ? 125.813 129.784 105.866 1.00 55.66  ? 765  TRP A CE3 1 
ATOM   5128 C CZ2 . TRP A 1 806  ? 125.435 130.067 108.648 1.00 55.66  ? 765  TRP A CZ2 1 
ATOM   5129 C CZ3 . TRP A 1 806  ? 126.863 130.065 106.709 1.00 55.66  ? 765  TRP A CZ3 1 
ATOM   5130 C CH2 . TRP A 1 806  ? 126.670 130.204 108.084 1.00 55.66  ? 765  TRP A CH2 1 
ATOM   5131 N N   . ASP A 1 807  ? 122.456 129.883 101.312 1.00 60.53  ? 766  ASP A N   1 
ATOM   5132 C CA  . ASP A 1 807  ? 122.610 129.535 99.907  1.00 60.53  ? 766  ASP A CA  1 
ATOM   5133 C C   . ASP A 1 807  ? 123.390 130.610 99.161  1.00 60.53  ? 766  ASP A C   1 
ATOM   5134 O O   . ASP A 1 807  ? 124.185 130.304 98.269  1.00 60.53  ? 766  ASP A O   1 
ATOM   5135 C CB  . ASP A 1 807  ? 121.246 129.314 99.263  1.00 60.53  ? 766  ASP A CB  1 
ATOM   5136 C CG  . ASP A 1 807  ? 121.325 128.417 98.053  1.00 60.53  ? 766  ASP A CG  1 
ATOM   5137 O OD1 . ASP A 1 807  ? 121.710 128.913 96.975  1.00 60.53  ? 766  ASP A OD1 1 
ATOM   5138 O OD2 . ASP A 1 807  ? 121.023 127.214 98.182  1.00 60.53  ? 766  ASP A OD2 1 
ATOM   5139 N N   . ILE A 1 808  ? 123.172 131.879 99.510  1.00 58.07  ? 767  ILE A N   1 
ATOM   5140 C CA  . ILE A 1 808  ? 123.965 132.950 98.911  1.00 58.07  ? 767  ILE A CA  1 
ATOM   5141 C C   . ILE A 1 808  ? 125.442 132.755 99.228  1.00 58.07  ? 767  ILE A C   1 
ATOM   5142 O O   . ILE A 1 808  ? 126.309 132.853 98.346  1.00 58.07  ? 767  ILE A O   1 
ATOM   5143 C CB  . ILE A 1 808  ? 123.462 134.324 99.385  1.00 58.07  ? 767  ILE A CB  1 
ATOM   5144 C CG1 . ILE A 1 808  ? 122.103 134.636 98.763  1.00 58.07  ? 767  ILE A CG1 1 
ATOM   5145 C CG2 . ILE A 1 808  ? 124.472 135.405 99.061  1.00 58.07  ? 767  ILE A CG2 1 
ATOM   5146 C CD1 . ILE A 1 808  ? 121.486 135.915 99.267  1.00 58.07  ? 767  ILE A CD1 1 
ATOM   5147 N N   . VAL A 1 809  ? 125.747 132.456 100.492 1.00 57.77  ? 768  VAL A N   1 
ATOM   5148 C CA  . VAL A 1 809  ? 127.133 132.205 100.888 1.00 57.77  ? 768  VAL A CA  1 
ATOM   5149 C C   . VAL A 1 809  ? 127.725 131.064 100.069 1.00 57.77  ? 768  VAL A C   1 
ATOM   5150 O O   . VAL A 1 809  ? 128.827 131.175 99.511  1.00 57.77  ? 768  VAL A O   1 
ATOM   5151 C CB  . VAL A 1 809  ? 127.209 131.910 102.396 1.00 57.77  ? 768  VAL A CB  1 
ATOM   5152 C CG1 . VAL A 1 809  ? 128.607 131.487 102.780 1.00 57.77  ? 768  VAL A CG1 1 
ATOM   5153 C CG2 . VAL A 1 809  ? 126.793 133.126 103.192 1.00 57.77  ? 768  VAL A CG2 1 
ATOM   5154 N N   . GLY A 1 810  ? 126.991 129.955 99.970  1.00 63.26  ? 769  GLY A N   1 
ATOM   5155 C CA  . GLY A 1 810  ? 127.515 128.793 99.269  1.00 63.26  ? 769  GLY A CA  1 
ATOM   5156 C C   . GLY A 1 810  ? 127.736 129.043 97.789  1.00 63.26  ? 769  GLY A C   1 
ATOM   5157 O O   . GLY A 1 810  ? 128.755 128.636 97.224  1.00 63.26  ? 769  GLY A O   1 
ATOM   5158 N N   . GLU A 1 811  ? 126.778 129.702 97.136  1.00 62.78  ? 770  GLU A N   1 
ATOM   5159 C CA  . GLU A 1 811  ? 126.914 129.976 95.710  1.00 62.78  ? 770  GLU A CA  1 
ATOM   5160 C C   . GLU A 1 811  ? 128.093 130.897 95.437  1.00 62.78  ? 770  GLU A C   1 
ATOM   5161 O O   . GLU A 1 811  ? 128.856 130.680 94.485  1.00 62.78  ? 770  GLU A O   1 
ATOM   5162 C CB  . GLU A 1 811  ? 125.625 130.576 95.156  1.00 62.78  ? 770  GLU A CB  1 
ATOM   5163 C CG  . GLU A 1 811  ? 124.428 129.658 95.242  1.00 62.78  ? 770  GLU A CG  1 
ATOM   5164 C CD  . GLU A 1 811  ? 124.606 128.395 94.429  1.00 62.78  ? 770  GLU A CD  1 
ATOM   5165 O OE1 . GLU A 1 811  ? 124.747 127.311 95.034  1.00 62.78  ? 770  GLU A OE1 1 
ATOM   5166 O OE2 . GLU A 1 811  ? 124.606 128.481 93.185  1.00 62.78  ? 770  GLU A OE2 1 
ATOM   5167 N N   . ASN A 1 812  ? 128.262 131.938 96.257  1.00 60.66  ? 771  ASN A N   1 
ATOM   5168 C CA  . ASN A 1 812  ? 129.404 132.822 96.053  1.00 60.66  ? 771  ASN A CA  1 
ATOM   5169 C C   . ASN A 1 812  ? 130.716 132.074 96.244  1.00 60.66  ? 771  ASN A C   1 
ATOM   5170 O O   . ASN A 1 812  ? 131.669 132.272 95.476  1.00 60.66  ? 771  ASN A O   1 
ATOM   5171 C CB  . ASN A 1 812  ? 129.315 134.026 96.987  1.00 60.66  ? 771  ASN A CB  1 
ATOM   5172 C CG  . ASN A 1 812  ? 128.149 134.929 96.648  1.00 60.66  ? 771  ASN A CG  1 
ATOM   5173 O OD1 . ASN A 1 812  ? 127.368 134.634 95.747  1.00 60.66  ? 771  ASN A OD1 1 
ATOM   5174 N ND2 . ASN A 1 812  ? 128.031 136.040 97.360  1.00 60.66  ? 771  ASN A ND2 1 
ATOM   5175 N N   . LEU A 1 813  ? 130.781 131.191 97.243  1.00 62.43  ? 772  LEU A N   1 
ATOM   5176 C CA  . LEU A 1 813  ? 132.003 130.419 97.449  1.00 62.43  ? 772  LEU A CA  1 
ATOM   5177 C C   . LEU A 1 813  ? 132.298 129.519 96.254  1.00 62.43  ? 772  LEU A C   1 
ATOM   5178 O O   . LEU A 1 813  ? 133.446 129.434 95.798  1.00 62.43  ? 772  LEU A O   1 
ATOM   5179 C CB  . LEU A 1 813  ? 131.903 129.595 98.728  1.00 62.43  ? 772  LEU A CB  1 
ATOM   5180 C CG  . LEU A 1 813  ? 133.070 128.634 98.935  1.00 62.43  ? 772  LEU A CG  1 
ATOM   5181 C CD1 . LEU A 1 813  ? 134.320 129.406 99.306  1.00 62.43  ? 772  LEU A CD1 1 
ATOM   5182 C CD2 . LEU A 1 813  ? 132.741 127.609 99.999  1.00 62.43  ? 772  LEU A CD2 1 
ATOM   5183 N N   . THR A 1 814  ? 131.277 128.830 95.736  1.00 62.45  ? 773  THR A N   1 
ATOM   5184 C CA  . THR A 1 814  ? 131.498 127.955 94.586  1.00 62.45  ? 773  THR A CA  1 
ATOM   5185 C C   . THR A 1 814  ? 131.986 128.743 93.385  1.00 62.45  ? 773  THR A C   1 
ATOM   5186 O O   . THR A 1 814  ? 132.916 128.320 92.690  1.00 62.45  ? 773  THR A O   1 
ATOM   5187 C CB  . THR A 1 814  ? 130.228 127.197 94.210  1.00 62.45  ? 773  THR A CB  1 
ATOM   5188 O OG1 . THR A 1 814  ? 129.182 128.127 93.905  1.00 62.45  ? 773  THR A OG1 1 
ATOM   5189 C CG2 . THR A 1 814  ? 129.807 126.289 95.313  1.00 62.45  ? 773  THR A CG2 1 
ATOM   5190 N N   . LYS A 1 815  ? 131.357 129.885 93.108  1.00 62.88  ? 774  LYS A N   1 
ATOM   5191 C CA  . LYS A 1 815  ? 131.774 130.676 91.957  1.00 62.88  ? 774  LYS A CA  1 
ATOM   5192 C C   . LYS A 1 815  ? 133.221 131.120 92.104  1.00 62.88  ? 774  LYS A C   1 
ATOM   5193 O O   . LYS A 1 815  ? 134.022 130.980 91.171  1.00 62.88  ? 774  LYS A O   1 
ATOM   5194 C CB  . LYS A 1 815  ? 130.851 131.878 91.782  1.00 62.88  ? 774  LYS A CB  1 
ATOM   5195 C CG  . LYS A 1 815  ? 131.200 132.741 90.588  1.00 62.88  ? 774  LYS A CG  1 
ATOM   5196 C CD  . LYS A 1 815  ? 130.092 133.728 90.282  1.00 62.88  ? 774  LYS A CD  1 
ATOM   5197 C CE  . LYS A 1 815  ? 130.394 134.518 89.026  1.00 62.88  ? 774  LYS A CE  1 
ATOM   5198 N NZ  . LYS A 1 815  ? 131.620 135.340 89.182  1.00 62.88  ? 774  LYS A NZ  1 
ATOM   5199 N N   . ARG A 1 816  ? 133.585 131.632 93.281  1.00 64.69  ? 775  ARG A N   1 
ATOM   5200 C CA  . ARG A 1 816  ? 134.950 132.102 93.487  1.00 64.69  ? 775  ARG A CA  1 
ATOM   5201 C C   . ARG A 1 816  ? 135.954 130.971 93.305  1.00 64.69  ? 775  ARG A C   1 
ATOM   5202 O O   . ARG A 1 816  ? 136.971 131.126 92.613  1.00 64.69  ? 775  ARG A O   1 
ATOM   5203 C CB  . ARG A 1 816  ? 135.078 132.718 94.877  1.00 64.69  ? 775  ARG A CB  1 
ATOM   5204 C CG  . ARG A 1 816  ? 136.460 133.238 95.210  1.00 64.69  ? 775  ARG A CG  1 
ATOM   5205 C CD  . ARG A 1 816  ? 136.379 134.326 96.266  1.00 64.69  ? 775  ARG A CD  1 
ATOM   5206 N NE  . ARG A 1 816  ? 135.334 135.296 95.965  1.00 64.69  ? 775  ARG A NE  1 
ATOM   5207 C CZ  . ARG A 1 816  ? 134.270 135.510 96.725  1.00 64.69  ? 775  ARG A CZ  1 
ATOM   5208 N NH1 . ARG A 1 816  ? 134.071 134.831 97.844  1.00 64.69  ? 775  ARG A NH1 1 
ATOM   5209 N NH2 . ARG A 1 816  ? 133.379 136.425 96.353  1.00 64.69  ? 775  ARG A NH2 1 
ATOM   5210 N N   . VAL A 1 817  ? 135.675 129.811 93.903  1.00 64.72  ? 776  VAL A N   1 
ATOM   5211 C CA  . VAL A 1 817  ? 136.608 128.691 93.825  1.00 64.72  ? 776  VAL A CA  1 
ATOM   5212 C C   . VAL A 1 817  ? 136.735 128.203 92.388  1.00 64.72  ? 776  VAL A C   1 
ATOM   5213 O O   . VAL A 1 817  ? 137.830 127.873 91.924  1.00 64.72  ? 776  VAL A O   1 
ATOM   5214 C CB  . VAL A 1 817  ? 136.171 127.561 94.774  1.00 64.72  ? 776  VAL A CB  1 
ATOM   5215 C CG1 . VAL A 1 817  ? 136.899 126.277 94.443  1.00 64.72  ? 776  VAL A CG1 1 
ATOM   5216 C CG2 . VAL A 1 817  ? 136.442 127.956 96.209  1.00 64.72  ? 776  VAL A CG2 1 
ATOM   5217 N N   . ARG A 1 818  ? 135.617 128.141 91.664  1.00 67.08  ? 777  ARG A N   1 
ATOM   5218 C CA  . ARG A 1 818  ? 135.655 127.657 90.287  1.00 67.08  ? 777  ARG A CA  1 
ATOM   5219 C C   . ARG A 1 818  ? 136.468 128.588 89.396  1.00 67.08  ? 777  ARG A C   1 
ATOM   5220 O O   . ARG A 1 818  ? 137.271 128.132 88.570  1.00 67.08  ? 777  ARG A O   1 
ATOM   5221 C CB  . ARG A 1 818  ? 134.231 127.497 89.760  1.00 67.08  ? 777  ARG A CB  1 
ATOM   5222 C CG  . ARG A 1 818  ? 133.619 126.138 90.035  1.00 67.08  ? 777  ARG A CG  1 
ATOM   5223 C CD  . ARG A 1 818  ? 132.457 125.864 89.102  1.00 67.08  ? 777  ARG A CD  1 
ATOM   5224 N NE  . ARG A 1 818  ? 131.169 126.050 89.757  1.00 67.08  ? 777  ARG A NE  1 
ATOM   5225 C CZ  . ARG A 1 818  ? 130.403 125.058 90.190  1.00 67.08  ? 777  ARG A CZ  1 
ATOM   5226 N NH1 . ARG A 1 818  ? 130.747 123.793 90.016  1.00 67.08  ? 777  ARG A NH1 1 
ATOM   5227 N NH2 . ARG A 1 818  ? 129.260 125.344 90.805  1.00 67.08  ? 777  ARG A NH2 1 
ATOM   5228 N N   . GLU A 1 819  ? 136.278 129.900 89.547  1.00 68.38  ? 778  GLU A N   1 
ATOM   5229 C CA  . GLU A 1 819  ? 137.075 130.841 88.766  1.00 68.38  ? 778  GLU A CA  1 
ATOM   5230 C C   . GLU A 1 819  ? 138.555 130.716 89.097  1.00 68.38  ? 778  GLU A C   1 
ATOM   5231 O O   . GLU A 1 819  ? 139.410 130.738 88.199  1.00 68.38  ? 778  GLU A O   1 
ATOM   5232 C CB  . GLU A 1 819  ? 136.594 132.272 88.997  1.00 68.38  ? 778  GLU A CB  1 
ATOM   5233 C CG  . GLU A 1 819  ? 135.108 132.456 88.846  1.00 68.38  ? 778  GLU A CG  1 
ATOM   5234 C CD  . GLU A 1 819  ? 134.735 133.873 88.487  1.00 68.38  ? 778  GLU A CD  1 
ATOM   5235 O OE1 . GLU A 1 819  ? 134.302 134.097 87.343  1.00 68.38  ? 778  GLU A OE1 1 
ATOM   5236 O OE2 . GLU A 1 819  ? 134.871 134.762 89.352  1.00 68.38  ? 778  GLU A OE2 1 
ATOM   5237 N N   . LYS A 1 820  ? 138.884 130.585 90.385  1.00 71.82  ? 779  LYS A N   1 
ATOM   5238 C CA  . LYS A 1 820  ? 140.286 130.428 90.758  1.00 71.82  ? 779  LYS A CA  1 
ATOM   5239 C C   . LYS A 1 820  ? 140.874 129.152 90.168  1.00 71.82  ? 779  LYS A C   1 
ATOM   5240 O O   . LYS A 1 820  ? 142.015 129.148 89.689  1.00 71.82  ? 779  LYS A O   1 
ATOM   5241 C CB  . LYS A 1 820  ? 140.435 130.439 92.277  1.00 71.82  ? 779  LYS A CB  1 
ATOM   5242 C CG  . LYS A 1 820  ? 140.124 131.780 92.909  1.00 71.82  ? 779  LYS A CG  1 
ATOM   5243 C CD  . LYS A 1 820  ? 140.158 131.701 94.420  1.00 71.82  ? 779  LYS A CD  1 
ATOM   5244 C CE  . LYS A 1 820  ? 141.332 132.479 94.980  1.00 71.82  ? 779  LYS A CE  1 
ATOM   5245 N NZ  . LYS A 1 820  ? 141.027 133.931 95.090  1.00 71.82  ? 779  LYS A NZ  1 
ATOM   5246 N N   . MET A 1 821  ? 140.107 128.061 90.189  1.00 75.40  ? 780  MET A N   1 
ATOM   5247 C CA  . MET A 1 821  ? 140.584 126.805 89.623  1.00 75.40  ? 780  MET A CA  1 
ATOM   5248 C C   . MET A 1 821  ? 140.849 126.943 88.131  1.00 75.40  ? 780  MET A C   1 
ATOM   5249 O O   . MET A 1 821  ? 141.870 126.466 87.627  1.00 75.40  ? 780  MET A O   1 
ATOM   5250 C CB  . MET A 1 821  ? 139.574 125.687 89.876  1.00 75.40  ? 780  MET A CB  1 
ATOM   5251 C CG  . MET A 1 821  ? 139.594 125.121 91.275  1.00 75.40  ? 780  MET A CG  1 
ATOM   5252 S SD  . MET A 1 821  ? 138.695 123.567 91.374  1.00 75.40  ? 780  MET A SD  1 
ATOM   5253 C CE  . MET A 1 821  ? 137.042 124.109 90.958  1.00 75.40  ? 780  MET A CE  1 
ATOM   5254 N N   . LEU A 1 822  ? 139.935 127.589 87.405  1.00 71.06  ? 781  LEU A N   1 
ATOM   5255 C CA  . LEU A 1 822  ? 140.132 127.732 85.966  1.00 71.06  ? 781  LEU A CA  1 
ATOM   5256 C C   . LEU A 1 822  ? 141.354 128.590 85.665  1.00 71.06  ? 781  LEU A C   1 
ATOM   5257 O O   . LEU A 1 822  ? 142.141 128.277 84.765  1.00 71.06  ? 781  LEU A O   1 
ATOM   5258 C CB  . LEU A 1 822  ? 138.892 128.323 85.304  1.00 71.06  ? 781  LEU A CB  1 
ATOM   5259 C CG  . LEU A 1 822  ? 139.099 128.553 83.805  1.00 71.06  ? 781  LEU A CG  1 
ATOM   5260 C CD1 . LEU A 1 822  ? 139.452 127.246 83.114  1.00 71.06  ? 781  LEU A CD1 1 
ATOM   5261 C CD2 . LEU A 1 822  ? 137.892 129.194 83.155  1.00 71.06  ? 781  LEU A CD2 1 
ATOM   5262 N N   . SER A 1 823  ? 141.532 129.683 86.410  1.00 73.87  ? 782  SER A N   1 
ATOM   5263 C CA  . SER A 1 823  ? 142.701 130.529 86.189  1.00 73.87  ? 782  SER A CA  1 
ATOM   5264 C C   . SER A 1 823  ? 143.991 129.759 86.453  1.00 73.87  ? 782  SER A C   1 
ATOM   5265 O O   . SER A 1 823  ? 144.938 129.812 85.656  1.00 73.87  ? 782  SER A O   1 
ATOM   5266 C CB  . SER A 1 823  ? 142.622 131.771 87.073  1.00 73.87  ? 782  SER A CB  1 
ATOM   5267 O OG  . SER A 1 823  ? 143.711 132.638 86.824  1.00 73.87  ? 782  SER A OG  1 
ATOM   5268 N N   . ALA A 1 824  ? 144.033 129.014 87.559  1.00 76.38  ? 783  ALA A N   1 
ATOM   5269 C CA  . ALA A 1 824  ? 145.226 128.238 87.879  1.00 76.38  ? 783  ALA A CA  1 
ATOM   5270 C C   . ALA A 1 824  ? 145.496 127.180 86.819  1.00 76.38  ? 783  ALA A C   1 
ATOM   5271 O O   . ALA A 1 824  ? 146.653 126.932 86.462  1.00 76.38  ? 783  ALA A O   1 
ATOM   5272 C CB  . ALA A 1 824  ? 145.081 127.593 89.256  1.00 76.38  ? 783  ALA A CB  1 
ATOM   5273 N N   . VAL A 1 825  ? 144.442 126.545 86.308  1.00 75.07  ? 784  VAL A N   1 
ATOM   5274 C CA  . VAL A 1 825  ? 144.611 125.557 85.245  1.00 75.07  ? 784  VAL A CA  1 
ATOM   5275 C C   . VAL A 1 825  ? 145.203 126.210 84.006  1.00 75.07  ? 784  VAL A C   1 
ATOM   5276 O O   . VAL A 1 825  ? 146.130 125.679 83.384  1.00 75.07  ? 784  VAL A O   1 
ATOM   5277 C CB  . VAL A 1 825  ? 143.268 124.871 84.935  1.00 75.07  ? 784  VAL A CB  1 
ATOM   5278 C CG1 . VAL A 1 825  ? 143.307 124.221 83.566  1.00 75.07  ? 784  VAL A CG1 1 
ATOM   5279 C CG2 . VAL A 1 825  ? 142.943 123.845 86.000  1.00 75.07  ? 784  VAL A CG2 1 
ATOM   5280 N N   . LEU A 1 826  ? 144.685 127.380 83.632  1.00 74.19  ? 785  LEU A N   1 
ATOM   5281 C CA  . LEU A 1 826  ? 145.135 128.011 82.397  1.00 74.19  ? 785  LEU A CA  1 
ATOM   5282 C C   . LEU A 1 826  ? 146.549 128.562 82.526  1.00 74.19  ? 785  LEU A C   1 
ATOM   5283 O O   . LEU A 1 826  ? 147.225 128.783 81.515  1.00 74.19  ? 785  LEU A O   1 
ATOM   5284 C CB  . LEU A 1 826  ? 144.163 129.112 81.978  1.00 74.19  ? 785  LEU A CB  1 
ATOM   5285 C CG  . LEU A 1 826  ? 142.772 128.616 81.587  1.00 74.19  ? 785  LEU A CG  1 
ATOM   5286 C CD1 . LEU A 1 826  ? 141.851 129.785 81.306  1.00 74.19  ? 785  LEU A CD1 1 
ATOM   5287 C CD2 . LEU A 1 826  ? 142.850 127.688 80.391  1.00 74.19  ? 785  LEU A CD2 1 
ATOM   5288 N N   . LYS A 1 827  ? 147.018 128.801 83.754  1.00 86.09  ? 786  LYS A N   1 
ATOM   5289 C CA  . LYS A 1 827  ? 148.399 129.256 83.904  1.00 86.09  ? 786  LYS A CA  1 
ATOM   5290 C C   . LYS A 1 827  ? 149.410 128.146 83.632  1.00 86.09  ? 786  LYS A C   1 
ATOM   5291 O O   . LYS A 1 827  ? 150.581 128.432 83.366  1.00 86.09  ? 786  LYS A O   1 
ATOM   5292 C CB  . LYS A 1 827  ? 148.632 129.843 85.295  1.00 86.09  ? 786  LYS A CB  1 
ATOM   5293 C CG  . LYS A 1 827  ? 147.867 131.119 85.572  1.00 86.09  ? 786  LYS A CG  1 
ATOM   5294 C CD  . LYS A 1 827  ? 148.169 131.640 86.964  1.00 86.09  ? 786  LYS A CD  1 
ATOM   5295 C CE  . LYS A 1 827  ? 147.479 132.967 87.216  1.00 86.09  ? 786  LYS A CE  1 
ATOM   5296 N NZ  . LYS A 1 827  ? 146.000 132.823 87.256  1.00 86.09  ? 786  LYS A NZ  1 
ATOM   5297 N N   . ASN A 1 828  ? 148.988 126.884 83.695  1.00 93.56  ? 787  ASN A N   1 
ATOM   5298 C CA  . ASN A 1 828  ? 149.927 125.778 83.544  1.00 93.56  ? 787  ASN A CA  1 
ATOM   5299 C C   . ASN A 1 828  ? 150.400 125.641 82.099  1.00 93.56  ? 787  ASN A C   1 
ATOM   5300 O O   . ASN A 1 828  ? 149.724 126.061 81.157  1.00 93.56  ? 787  ASN A O   1 
ATOM   5301 C CB  . ASN A 1 828  ? 149.287 124.472 84.008  1.00 93.56  ? 787  ASN A CB  1 
ATOM   5302 C CG  . ASN A 1 828  ? 148.979 124.472 85.486  1.00 93.56  ? 787  ASN A CG  1 
ATOM   5303 O OD1 . ASN A 1 828  ? 149.455 125.328 86.229  1.00 93.56  ? 787  ASN A OD1 1 
ATOM   5304 N ND2 . ASN A 1 828  ? 148.174 123.512 85.923  1.00 93.56  ? 787  ASN A ND2 1 
ATOM   5305 N N   . GLU A 1 829  ? 151.577 125.040 81.934  1.00 107.10 ? 788  GLU A N   1 
ATOM   5306 C CA  . GLU A 1 829  ? 152.167 124.860 80.617  1.00 107.10 ? 788  GLU A CA  1 
ATOM   5307 C C   . GLU A 1 829  ? 151.618 123.601 79.947  1.00 107.10 ? 788  GLU A C   1 
ATOM   5308 O O   . GLU A 1 829  ? 150.894 122.803 80.549  1.00 107.10 ? 788  GLU A O   1 
ATOM   5309 C CB  . GLU A 1 829  ? 153.688 124.777 80.715  1.00 107.10 ? 788  GLU A CB  1 
ATOM   5310 C CG  . GLU A 1 829  ? 154.195 123.409 81.116  1.00 107.10 ? 788  GLU A CG  1 
ATOM   5311 C CD  . GLU A 1 829  ? 154.116 123.182 82.606  1.00 107.10 ? 788  GLU A CD  1 
ATOM   5312 O OE1 . GLU A 1 829  ? 154.078 122.008 83.030  1.00 107.10 ? 788  GLU A OE1 1 
ATOM   5313 O OE2 . GLU A 1 829  ? 154.093 124.180 83.354  1.00 107.10 ? 788  GLU A OE2 1 
ATOM   5314 N N   . MET A 1 830  ? 151.988 123.423 78.675  1.00 105.53 ? 789  MET A N   1 
ATOM   5315 C CA  . MET A 1 830  ? 151.428 122.331 77.883  1.00 105.53 ? 789  MET A CA  1 
ATOM   5316 C C   . MET A 1 830  ? 151.912 120.969 78.360  1.00 105.53 ? 789  MET A C   1 
ATOM   5317 O O   . MET A 1 830  ? 151.216 119.966 78.173  1.00 105.53 ? 789  MET A O   1 
ATOM   5318 C CB  . MET A 1 830  ? 151.769 122.524 76.406  1.00 105.53 ? 789  MET A CB  1 
ATOM   5319 C CG  . MET A 1 830  ? 150.751 123.353 75.647  1.00 105.53 ? 789  MET A CG  1 
ATOM   5320 S SD  . MET A 1 830  ? 149.221 122.475 75.279  1.00 105.53 ? 789  MET A SD  1 
ATOM   5321 C CE  . MET A 1 830  ? 149.817 120.802 75.059  1.00 105.53 ? 789  MET A CE  1 
ATOM   5322 N N   . ALA A 1 831  ? 153.103 120.907 78.961  1.00 108.27 ? 790  ALA A N   1 
ATOM   5323 C CA  . ALA A 1 831  ? 153.583 119.640 79.500  1.00 108.27 ? 790  ALA A CA  1 
ATOM   5324 C C   . ALA A 1 831  ? 152.641 119.117 80.574  1.00 108.27 ? 790  ALA A C   1 
ATOM   5325 O O   . ALA A 1 831  ? 152.391 117.910 80.662  1.00 108.27 ? 790  ALA A O   1 
ATOM   5326 C CB  . ALA A 1 831  ? 154.996 119.804 80.057  1.00 108.27 ? 790  ALA A CB  1 
ATOM   5327 N N   . TRP A 1 832  ? 152.106 120.019 81.399  1.00 102.78 ? 791  TRP A N   1 
ATOM   5328 C CA  . TRP A 1 832  ? 151.119 119.629 82.397  1.00 102.78 ? 791  TRP A CA  1 
ATOM   5329 C C   . TRP A 1 832  ? 149.859 119.081 81.737  1.00 102.78 ? 791  TRP A C   1 
ATOM   5330 O O   . TRP A 1 832  ? 149.219 118.166 82.267  1.00 102.78 ? 791  TRP A O   1 
ATOM   5331 C CB  . TRP A 1 832  ? 150.796 120.829 83.285  1.00 102.78 ? 791  TRP A CB  1 
ATOM   5332 C CG  . TRP A 1 832  ? 149.881 120.543 84.426  1.00 102.78 ? 791  TRP A CG  1 
ATOM   5333 C CD1 . TRP A 1 832  ? 150.227 120.075 85.657  1.00 102.78 ? 791  TRP A CD1 1 
ATOM   5334 C CD2 . TRP A 1 832  ? 148.464 120.733 84.453  1.00 102.78 ? 791  TRP A CD2 1 
ATOM   5335 N NE1 . TRP A 1 832  ? 149.114 119.954 86.448  1.00 102.78 ? 791  TRP A NE1 1 
ATOM   5336 C CE2 . TRP A 1 832  ? 148.018 120.356 85.732  1.00 102.78 ? 791  TRP A CE2 1 
ATOM   5337 C CE3 . TRP A 1 832  ? 147.529 121.185 83.520  1.00 102.78 ? 791  TRP A CE3 1 
ATOM   5338 C CZ2 . TRP A 1 832  ? 146.677 120.408 86.099  1.00 102.78 ? 791  TRP A CZ2 1 
ATOM   5339 C CZ3 . TRP A 1 832  ? 146.202 121.237 83.886  1.00 102.78 ? 791  TRP A CZ3 1 
ATOM   5340 C CH2 . TRP A 1 832  ? 145.788 120.852 85.163  1.00 102.78 ? 791  TRP A CH2 1 
ATOM   5341 N N   . PHE A 1 833  ? 149.488 119.630 80.578  1.00 102.81 ? 792  PHE A N   1 
ATOM   5342 C CA  . PHE A 1 833  ? 148.292 119.158 79.886  1.00 102.81 ? 792  PHE A CA  1 
ATOM   5343 C C   . PHE A 1 833  ? 148.532 117.807 79.225  1.00 102.81 ? 792  PHE A C   1 
ATOM   5344 O O   . PHE A 1 833  ? 147.597 117.015 79.054  1.00 102.81 ? 792  PHE A O   1 
ATOM   5345 C CB  . PHE A 1 833  ? 147.846 120.190 78.850  1.00 102.81 ? 792  PHE A CB  1 
ATOM   5346 C CG  . PHE A 1 833  ? 147.309 121.457 79.451  1.00 102.81 ? 792  PHE A CG  1 
ATOM   5347 C CD1 . PHE A 1 833  ? 146.078 121.471 80.082  1.00 102.81 ? 792  PHE A CD1 1 
ATOM   5348 C CD2 . PHE A 1 833  ? 148.040 122.628 79.395  1.00 102.81 ? 792  PHE A CD2 1 
ATOM   5349 C CE1 . PHE A 1 833  ? 145.585 122.632 80.638  1.00 102.81 ? 792  PHE A CE1 1 
ATOM   5350 C CE2 . PHE A 1 833  ? 147.553 123.791 79.952  1.00 102.81 ? 792  PHE A CE2 1 
ATOM   5351 C CZ  . PHE A 1 833  ? 146.324 123.792 80.573  1.00 102.81 ? 792  PHE A CZ  1 
ATOM   5352 N N   . ASP A 1 834  ? 149.776 117.530 78.835  1.00 109.46 ? 793  ASP A N   1 
ATOM   5353 C CA  . ASP A 1 834  ? 150.083 116.253 78.200  1.00 109.46 ? 793  ASP A CA  1 
ATOM   5354 C C   . ASP A 1 834  ? 149.956 115.096 79.181  1.00 109.46 ? 793  ASP A C   1 
ATOM   5355 O O   . ASP A 1 834  ? 149.632 113.970 78.786  1.00 109.46 ? 793  ASP A O   1 
ATOM   5356 C CB  . ASP A 1 834  ? 151.486 116.289 77.600  1.00 109.46 ? 793  ASP A CB  1 
ATOM   5357 C CG  . ASP A 1 834  ? 151.580 117.211 76.409  1.00 109.46 ? 793  ASP A CG  1 
ATOM   5358 O OD1 . ASP A 1 834  ? 150.533 117.742 75.983  1.00 109.46 ? 793  ASP A OD1 1 
ATOM   5359 O OD2 . ASP A 1 834  ? 152.699 117.403 75.894  1.00 109.46 ? 793  ASP A OD2 1 
ATOM   5360 N N   . GLN A 1 835  ? 150.205 115.351 80.463  1.00 108.32 ? 794  GLN A N   1 
ATOM   5361 C CA  . GLN A 1 835  ? 150.192 114.291 81.462  1.00 108.32 ? 794  GLN A CA  1 
ATOM   5362 C C   . GLN A 1 835  ? 148.805 113.674 81.580  1.00 108.32 ? 794  GLN A C   1 
ATOM   5363 O O   . GLN A 1 835  ? 147.804 114.261 81.161  1.00 108.32 ? 794  GLN A O   1 
ATOM   5364 C CB  . GLN A 1 835  ? 150.632 114.842 82.819  1.00 108.32 ? 794  GLN A CB  1 
ATOM   5365 C CG  . GLN A 1 835  ? 152.118 115.140 82.922  1.00 108.32 ? 794  GLN A CG  1 
ATOM   5366 C CD  . GLN A 1 835  ? 152.504 115.682 84.285  1.00 108.32 ? 794  GLN A CD  1 
ATOM   5367 O OE1 . GLN A 1 835  ? 151.864 115.377 85.290  1.00 108.32 ? 794  GLN A OE1 1 
ATOM   5368 N NE2 . GLN A 1 835  ? 153.530 116.522 84.319  1.00 108.32 ? 794  GLN A NE2 1 
ATOM   5369 N N   . GLU A 1 836  ? 148.754 112.470 82.141  1.00 113.26 ? 795  GLU A N   1 
ATOM   5370 C CA  . GLU A 1 836  ? 147.493 111.776 82.349  1.00 113.26 ? 795  GLU A CA  1 
ATOM   5371 C C   . GLU A 1 836  ? 146.705 112.408 83.494  1.00 113.26 ? 795  GLU A C   1 
ATOM   5372 O O   . GLU A 1 836  ? 147.229 113.186 84.293  1.00 113.26 ? 795  GLU A O   1 
ATOM   5373 C CB  . GLU A 1 836  ? 147.740 110.293 82.622  1.00 113.26 ? 795  GLU A CB  1 
ATOM   5374 C CG  . GLU A 1 836  ? 148.506 109.596 81.514  1.00 113.26 ? 795  GLU A CG  1 
ATOM   5375 C CD  . GLU A 1 836  ? 147.912 109.867 80.149  1.00 113.26 ? 795  GLU A CD  1 
ATOM   5376 O OE1 . GLU A 1 836  ? 146.718 109.558 79.939  1.00 113.26 ? 795  GLU A OE1 1 
ATOM   5377 O OE2 . GLU A 1 836  ? 148.634 110.404 79.280  1.00 113.26 ? 795  GLU A OE2 1 
ATOM   5378 N N   . GLU A 1 837  ? 145.417 112.058 83.557  1.00 113.52 ? 796  GLU A N   1 
ATOM   5379 C CA  . GLU A 1 837  ? 144.450 112.653 84.485  1.00 113.52 ? 796  GLU A CA  1 
ATOM   5380 C C   . GLU A 1 837  ? 144.286 114.156 84.257  1.00 113.52 ? 796  GLU A C   1 
ATOM   5381 O O   . GLU A 1 837  ? 143.814 114.875 85.139  1.00 113.52 ? 796  GLU A O   1 
ATOM   5382 C CB  . GLU A 1 837  ? 144.832 112.367 85.943  1.00 113.52 ? 796  GLU A CB  1 
ATOM   5383 C CG  . GLU A 1 837  ? 144.552 110.940 86.399  1.00 113.52 ? 796  GLU A CG  1 
ATOM   5384 C CD  . GLU A 1 837  ? 145.629 109.964 85.977  1.00 113.52 ? 796  GLU A CD  1 
ATOM   5385 O OE1 . GLU A 1 837  ? 146.794 110.139 86.396  1.00 113.52 ? 796  GLU A OE1 1 
ATOM   5386 O OE2 . GLU A 1 837  ? 145.306 109.011 85.235  1.00 113.52 ? 796  GLU A OE2 1 
ATOM   5387 N N   . ASN A 1 838  ? 144.672 114.653 83.075  1.00 110.12 ? 797  ASN A N   1 
ATOM   5388 C CA  . ASN A 1 838  ? 144.789 116.096 82.891  1.00 110.12 ? 797  ASN A CA  1 
ATOM   5389 C C   . ASN A 1 838  ? 144.319 116.614 81.533  1.00 110.12 ? 797  ASN A C   1 
ATOM   5390 O O   . ASN A 1 838  ? 144.892 117.592 81.038  1.00 110.12 ? 797  ASN A O   1 
ATOM   5391 C CB  . ASN A 1 838  ? 146.244 116.561 83.070  1.00 110.12 ? 797  ASN A CB  1 
ATOM   5392 C CG  . ASN A 1 838  ? 146.696 116.562 84.515  1.00 110.12 ? 797  ASN A CG  1 
ATOM   5393 O OD1 . ASN A 1 838  ? 146.485 115.609 85.258  1.00 110.12 ? 797  ASN A OD1 1 
ATOM   5394 N ND2 . ASN A 1 838  ? 147.341 117.639 84.915  1.00 110.12 ? 797  ASN A ND2 1 
ATOM   5395 N N   . GLU A 1 839  ? 143.307 116.021 80.902  1.00 107.83 ? 798  GLU A N   1 
ATOM   5396 C CA  . GLU A 1 839  ? 142.929 116.533 79.590  1.00 107.83 ? 798  GLU A CA  1 
ATOM   5397 C C   . GLU A 1 839  ? 141.468 116.240 79.276  1.00 107.83 ? 798  GLU A C   1 
ATOM   5398 O O   . GLU A 1 839  ? 140.928 115.195 79.638  1.00 107.83 ? 798  GLU A O   1 
ATOM   5399 C CB  . GLU A 1 839  ? 143.823 115.944 78.489  1.00 107.83 ? 798  GLU A CB  1 
ATOM   5400 C CG  . GLU A 1 839  ? 143.771 116.682 77.153  1.00 107.83 ? 798  GLU A CG  1 
ATOM   5401 C CD  . GLU A 1 839  ? 144.546 117.990 77.153  1.00 107.83 ? 798  GLU A CD  1 
ATOM   5402 O OE1 . GLU A 1 839  ? 145.194 118.309 78.173  1.00 107.83 ? 798  GLU A OE1 1 
ATOM   5403 O OE2 . GLU A 1 839  ? 144.517 118.695 76.122  1.00 107.83 ? 798  GLU A OE2 1 
ATOM   5404 N N   . SER A 1 840  ? 140.857 117.165 78.545  1.00 105.68 ? 799  SER A N   1 
ATOM   5405 C CA  . SER A 1 840  ? 139.522 117.038 77.925  1.00 105.68 ? 799  SER A CA  1 
ATOM   5406 C C   . SER A 1 840  ? 138.462 116.930 79.028  1.00 105.68 ? 799  SER A C   1 
ATOM   5407 O O   . SER A 1 840  ? 138.538 117.653 80.031  1.00 105.68 ? 799  SER A O   1 
ATOM   5408 C CB  . SER A 1 840  ? 139.528 115.891 76.931  1.00 105.68 ? 799  SER A CB  1 
ATOM   5409 O OG  . SER A 1 840  ? 139.645 114.641 77.583  1.00 105.68 ? 799  SER A OG  1 
ATOM   5410 N N   . ALA A 1 841  ? 137.465 116.052 78.874  1.00 104.66 ? 800  ALA A N   1 
ATOM   5411 C CA  . ALA A 1 841  ? 136.269 116.104 79.712  1.00 104.66 ? 800  ALA A CA  1 
ATOM   5412 C C   . ALA A 1 841  ? 136.549 115.703 81.153  1.00 104.66 ? 800  ALA A C   1 
ATOM   5413 O O   . ALA A 1 841  ? 135.752 116.001 82.042  1.00 104.66 ? 800  ALA A O   1 
ATOM   5414 C CB  . ALA A 1 841  ? 135.185 115.206 79.122  1.00 104.66 ? 800  ALA A CB  1 
ATOM   5415 N N   . ARG A 1 842  ? 137.670 115.037 81.397  1.00 107.98 ? 801  ARG A N   1 
ATOM   5416 C CA  . ARG A 1 842  ? 138.016 114.524 82.719  1.00 107.98 ? 801  ARG A CA  1 
ATOM   5417 C C   . ARG A 1 842  ? 138.516 115.619 83.669  1.00 107.98 ? 801  ARG A C   1 
ATOM   5418 O O   . ARG A 1 842  ? 138.164 115.635 84.858  1.00 107.98 ? 801  ARG A O   1 
ATOM   5419 C CB  . ARG A 1 842  ? 138.977 113.364 82.462  1.00 107.98 ? 801  ARG A CB  1 
ATOM   5420 C CG  . ARG A 1 842  ? 140.372 113.753 82.088  1.00 107.98 ? 801  ARG A CG  1 
ATOM   5421 C CD  . ARG A 1 842  ? 141.221 112.521 81.838  1.00 107.98 ? 801  ARG A CD  1 
ATOM   5422 N NE  . ARG A 1 842  ? 142.577 112.882 81.448  1.00 107.98 ? 801  ARG A NE  1 
ATOM   5423 C CZ  . ARG A 1 842  ? 143.577 112.023 81.323  1.00 107.98 ? 801  ARG A CZ  1 
ATOM   5424 N NH1 . ARG A 1 842  ? 143.428 110.741 81.615  1.00 107.98 ? 801  ARG A NH1 1 
ATOM   5425 N NH2 . ARG A 1 842  ? 144.745 112.455 80.855  1.00 107.98 ? 801  ARG A NH2 1 
ATOM   5426 N N   . ILE A 1 843  ? 139.263 116.597 83.153  1.00 100.04 ? 802  ILE A N   1 
ATOM   5427 C CA  . ILE A 1 843  ? 139.580 117.770 83.970  1.00 100.04 ? 802  ILE A CA  1 
ATOM   5428 C C   . ILE A 1 843  ? 138.322 118.599 84.224  1.00 100.04 ? 802  ILE A C   1 
ATOM   5429 O O   . ILE A 1 843  ? 138.124 119.142 85.319  1.00 100.04 ? 802  ILE A O   1 
ATOM   5430 C CB  . ILE A 1 843  ? 140.702 118.603 83.319  1.00 100.04 ? 802  ILE A CB  1 
ATOM   5431 C CG1 . ILE A 1 843  ? 141.313 119.566 84.334  1.00 100.04 ? 802  ILE A CG1 1 
ATOM   5432 C CG2 . ILE A 1 843  ? 140.206 119.376 82.115  1.00 100.04 ? 802  ILE A CG2 1 
ATOM   5433 C CD1 . ILE A 1 843  ? 142.644 120.121 83.900  1.00 100.04 ? 802  ILE A CD1 1 
ATOM   5434 N N   . ALA A 1 844  ? 137.441 118.697 83.227  1.00 99.11  ? 803  ALA A N   1 
ATOM   5435 C CA  . ALA A 1 844  ? 136.178 119.392 83.436  1.00 99.11  ? 803  ALA A CA  1 
ATOM   5436 C C   . ALA A 1 844  ? 135.345 118.681 84.493  1.00 99.11  ? 803  ALA A C   1 
ATOM   5437 O O   . ALA A 1 844  ? 134.673 119.321 85.307  1.00 99.11  ? 803  ALA A O   1 
ATOM   5438 C CB  . ALA A 1 844  ? 135.410 119.495 82.119  1.00 99.11  ? 803  ALA A CB  1 
ATOM   5439 N N   . ALA A 1 845  ? 135.383 117.349 84.489  1.00 98.16  ? 804  ALA A N   1 
ATOM   5440 C CA  . ALA A 1 845  ? 134.653 116.576 85.483  1.00 98.16  ? 804  ALA A CA  1 
ATOM   5441 C C   . ALA A 1 845  ? 135.193 116.821 86.883  1.00 98.16  ? 804  ALA A C   1 
ATOM   5442 O O   . ALA A 1 845  ? 134.416 116.972 87.831  1.00 98.16  ? 804  ALA A O   1 
ATOM   5443 C CB  . ALA A 1 845  ? 134.713 115.089 85.136  1.00 98.16  ? 804  ALA A CB  1 
ATOM   5444 N N   . ARG A 1 846  ? 136.519 116.860 87.045  1.00 97.72  ? 805  ARG A N   1 
ATOM   5445 C CA  . ARG A 1 846  ? 137.045 117.147 88.378  1.00 97.72  ? 805  ARG A CA  1 
ATOM   5446 C C   . ARG A 1 846  ? 136.644 118.550 88.824  1.00 97.72  ? 805  ARG A C   1 
ATOM   5447 O O   . ARG A 1 846  ? 136.237 118.754 89.975  1.00 97.72  ? 805  ARG A O   1 
ATOM   5448 C CB  . ARG A 1 846  ? 138.566 116.963 88.444  1.00 97.72  ? 805  ARG A CB  1 
ATOM   5449 C CG  . ARG A 1 846  ? 139.396 118.008 87.739  1.00 97.72  ? 805  ARG A CG  1 
ATOM   5450 C CD  . ARG A 1 846  ? 140.875 117.852 88.027  1.00 97.72  ? 805  ARG A CD  1 
ATOM   5451 N NE  . ARG A 1 846  ? 141.201 118.230 89.397  1.00 97.72  ? 805  ARG A NE  1 
ATOM   5452 C CZ  . ARG A 1 846  ? 142.378 118.027 89.970  1.00 97.72  ? 805  ARG A CZ  1 
ATOM   5453 N NH1 . ARG A 1 846  ? 143.376 117.455 89.316  1.00 97.72  ? 805  ARG A NH1 1 
ATOM   5454 N NH2 . ARG A 1 846  ? 142.562 118.414 91.229  1.00 97.72  ? 805  ARG A NH2 1 
ATOM   5455 N N   . LEU A 1 847  ? 136.707 119.528 87.912  1.00 92.57  ? 806  LEU A N   1 
ATOM   5456 C CA  . LEU A 1 847  ? 136.316 120.887 88.282  1.00 92.57  ? 806  LEU A CA  1 
ATOM   5457 C C   . LEU A 1 847  ? 134.843 120.961 88.667  1.00 92.57  ? 806  LEU A C   1 
ATOM   5458 O O   . LEU A 1 847  ? 134.477 121.672 89.609  1.00 92.57  ? 806  LEU A O   1 
ATOM   5459 C CB  . LEU A 1 847  ? 136.616 121.868 87.150  1.00 92.57  ? 806  LEU A CB  1 
ATOM   5460 C CG  . LEU A 1 847  ? 137.954 122.604 87.232  1.00 92.57  ? 806  LEU A CG  1 
ATOM   5461 C CD1 . LEU A 1 847  ? 139.122 121.674 86.967  1.00 92.57  ? 806  LEU A CD1 1 
ATOM   5462 C CD2 . LEU A 1 847  ? 137.971 123.793 86.286  1.00 92.57  ? 806  LEU A CD2 1 
ATOM   5463 N N   . ALA A 1 848  ? 133.983 120.244 87.947  1.00 93.64  ? 807  ALA A N   1 
ATOM   5464 C CA  . ALA A 1 848  ? 132.554 120.302 88.235  1.00 93.64  ? 807  ALA A CA  1 
ATOM   5465 C C   . ALA A 1 848  ? 132.222 119.580 89.536  1.00 93.64  ? 807  ALA A C   1 
ATOM   5466 O O   . ALA A 1 848  ? 131.376 120.040 90.312  1.00 93.64  ? 807  ALA A O   1 
ATOM   5467 C CB  . ALA A 1 848  ? 131.760 119.711 87.072  1.00 93.64  ? 807  ALA A CB  1 
ATOM   5468 N N   . LEU A 1 849  ? 132.875 118.447 89.794  1.00 95.98  ? 808  LEU A N   1 
ATOM   5469 C CA  . LEU A 1 849  ? 132.520 117.645 90.960  1.00 95.98  ? 808  LEU A CA  1 
ATOM   5470 C C   . LEU A 1 849  ? 133.189 118.125 92.238  1.00 95.98  ? 808  LEU A C   1 
ATOM   5471 O O   . LEU A 1 849  ? 132.758 117.738 93.329  1.00 95.98  ? 808  LEU A O   1 
ATOM   5472 C CB  . LEU A 1 849  ? 132.853 116.170 90.720  1.00 95.98  ? 808  LEU A CB  1 
ATOM   5473 C CG  . LEU A 1 849  ? 131.841 115.308 89.953  1.00 95.98  ? 808  LEU A CG  1 
ATOM   5474 C CD1 . LEU A 1 849  ? 130.541 115.201 90.737  1.00 95.98  ? 808  LEU A CD1 1 
ATOM   5475 C CD2 . LEU A 1 849  ? 131.569 115.815 88.545  1.00 95.98  ? 808  LEU A CD2 1 
ATOM   5476 N N   . ASP A 1 850  ? 134.232 118.946 92.150  1.00 96.53  ? 809  ASP A N   1 
ATOM   5477 C CA  . ASP A 1 850  ? 134.864 119.435 93.368  1.00 96.53  ? 809  ASP A CA  1 
ATOM   5478 C C   . ASP A 1 850  ? 134.462 120.856 93.746  1.00 96.53  ? 809  ASP A C   1 
ATOM   5479 O O   . ASP A 1 850  ? 135.289 121.589 94.293  1.00 96.53  ? 809  ASP A O   1 
ATOM   5480 C CB  . ASP A 1 850  ? 136.386 119.342 93.248  1.00 96.53  ? 809  ASP A CB  1 
ATOM   5481 C CG  . ASP A 1 850  ? 136.849 117.983 92.775  1.00 96.53  ? 809  ASP A CG  1 
ATOM   5482 O OD1 . ASP A 1 850  ? 136.174 116.983 93.091  1.00 96.53  ? 809  ASP A OD1 1 
ATOM   5483 O OD2 . ASP A 1 850  ? 137.889 117.914 92.086  1.00 96.53  ? 809  ASP A OD2 1 
ATOM   5484 N N   . ALA A 1 851  ? 133.228 121.272 93.464  1.00 91.69  ? 810  ALA A N   1 
ATOM   5485 C CA  . ALA A 1 851  ? 132.720 122.561 93.921  1.00 91.69  ? 810  ALA A CA  1 
ATOM   5486 C C   . ALA A 1 851  ? 131.423 122.443 94.711  1.00 91.69  ? 810  ALA A C   1 
ATOM   5487 O O   . ALA A 1 851  ? 131.242 123.125 95.730  1.00 91.69  ? 810  ALA A O   1 
ATOM   5488 C CB  . ALA A 1 851  ? 132.520 123.496 92.723  1.00 91.69  ? 810  ALA A CB  1 
ATOM   5489 N N   . ASN A 1 852  ? 130.501 121.598 94.251  1.00 93.74  ? 811  ASN A N   1 
ATOM   5490 C CA  . ASN A 1 852  ? 129.241 121.412 94.961  1.00 93.74  ? 811  ASN A CA  1 
ATOM   5491 C C   . ASN A 1 852  ? 129.466 120.778 96.330  1.00 93.74  ? 811  ASN A C   1 
ATOM   5492 O O   . ASN A 1 852  ? 128.857 121.180 97.328  1.00 93.74  ? 811  ASN A O   1 
ATOM   5493 C CB  . ASN A 1 852  ? 128.291 120.574 94.107  1.00 93.74  ? 811  ASN A CB  1 
ATOM   5494 C CG  . ASN A 1 852  ? 128.915 119.272 93.651  1.00 93.74  ? 811  ASN A CG  1 
ATOM   5495 O OD1 . ASN A 1 852  ? 130.018 118.919 94.068  1.00 93.74  ? 811  ASN A OD1 1 
ATOM   5496 N ND2 . ASN A 1 852  ? 128.217 118.555 92.780  1.00 93.74  ? 811  ASN A ND2 1 
ATOM   5497 N N   . ASN A 1 853  ? 130.346 119.782 96.403  1.00 99.65  ? 812  ASN A N   1 
ATOM   5498 C CA  . ASN A 1 853  ? 130.648 119.217 97.710  1.00 99.65  ? 812  ASN A CA  1 
ATOM   5499 C C   . ASN A 1 853  ? 131.402 120.208 98.587  1.00 99.65  ? 812  ASN A C   1 
ATOM   5500 O O   . ASN A 1 853  ? 131.313 120.133 99.815  1.00 99.65  ? 812  ASN A O   1 
ATOM   5501 C CB  . ASN A 1 853  ? 131.411 117.905 97.549  1.00 99.65  ? 812  ASN A CB  1 
ATOM   5502 C CG  . ASN A 1 853  ? 132.486 117.990 96.505  1.00 99.65  ? 812  ASN A CG  1 
ATOM   5503 O OD1 . ASN A 1 853  ? 132.898 119.079 96.111  1.00 99.65  ? 812  ASN A OD1 1 
ATOM   5504 N ND2 . ASN A 1 853  ? 132.928 116.836 96.020  1.00 99.65  ? 812  ASN A ND2 1 
ATOM   5505 N N   . VAL A 1 854  ? 132.102 121.173 97.984  1.00 90.08  ? 813  VAL A N   1 
ATOM   5506 C CA  . VAL A 1 854  ? 132.734 122.228 98.773  1.00 90.08  ? 813  VAL A CA  1 
ATOM   5507 C C   . VAL A 1 854  ? 131.682 123.136 99.400  1.00 90.08  ? 813  VAL A C   1 
ATOM   5508 O O   . VAL A 1 854  ? 131.751 123.463 100.596 1.00 90.08  ? 813  VAL A O   1 
ATOM   5509 C CB  . VAL A 1 854  ? 133.725 123.023 97.905  1.00 90.08  ? 813  VAL A CB  1 
ATOM   5510 C CG1 . VAL A 1 854  ? 134.276 124.202 98.679  1.00 90.08  ? 813  VAL A CG1 1 
ATOM   5511 C CG2 . VAL A 1 854  ? 134.850 122.121 97.448  1.00 90.08  ? 813  VAL A CG2 1 
ATOM   5512 N N   . ARG A 1 855  ? 130.695 123.564 98.607  1.00 80.89  ? 814  ARG A N   1 
ATOM   5513 C CA  . ARG A 1 855  ? 129.629 124.390 99.172  1.00 80.89  ? 814  ARG A CA  1 
ATOM   5514 C C   . ARG A 1 855  ? 128.906 123.630 100.272 1.00 80.89  ? 814  ARG A C   1 
ATOM   5515 O O   . ARG A 1 855  ? 128.575 124.198 101.320 1.00 80.89  ? 814  ARG A O   1 
ATOM   5516 C CB  . ARG A 1 855  ? 128.639 124.859 98.099  1.00 80.89  ? 814  ARG A CB  1 
ATOM   5517 C CG  . ARG A 1 855  ? 127.670 123.813 97.583  1.00 80.89  ? 814  ARG A CG  1 
ATOM   5518 C CD  . ARG A 1 855  ? 126.715 124.319 96.506  1.00 80.89  ? 814  ARG A CD  1 
ATOM   5519 N NE  . ARG A 1 855  ? 126.177 125.656 96.739  1.00 80.89  ? 814  ARG A NE  1 
ATOM   5520 C CZ  . ARG A 1 855  ? 125.440 126.010 97.784  1.00 80.89  ? 814  ARG A CZ  1 
ATOM   5521 N NH1 . ARG A 1 855  ? 125.120 125.149 98.735  1.00 80.89  ? 814  ARG A NH1 1 
ATOM   5522 N NH2 . ARG A 1 855  ? 124.995 127.261 97.866  1.00 80.89  ? 814  ARG A NH2 1 
ATOM   5523 N N   . SER A 1 856  ? 128.676 122.331 100.061 1.00 87.90  ? 815  SER A N   1 
ATOM   5524 C CA  . SER A 1 856  ? 128.070 121.528 101.115 1.00 87.90  ? 815  SER A CA  1 
ATOM   5525 C C   . SER A 1 856  ? 128.919 121.572 102.375 1.00 87.90  ? 815  SER A C   1 
ATOM   5526 O O   . SER A 1 856  ? 128.477 122.090 103.407 1.00 87.90  ? 815  SER A O   1 
ATOM   5527 C CB  . SER A 1 856  ? 127.880 120.086 100.646 1.00 87.90  ? 815  SER A CB  1 
ATOM   5528 O OG  . SER A 1 856  ? 129.124 119.424 100.522 1.00 87.90  ? 815  SER A OG  1 
ATOM   5529 N N   . ALA A 1 857  ? 130.174 121.130 102.277 1.00 90.68  ? 816  ALA A N   1 
ATOM   5530 C CA  . ALA A 1 857  ? 131.049 120.972 103.429 1.00 90.68  ? 816  ALA A CA  1 
ATOM   5531 C C   . ALA A 1 857  ? 131.350 122.280 104.141 1.00 90.68  ? 816  ALA A C   1 
ATOM   5532 O O   . ALA A 1 857  ? 131.840 122.240 105.275 1.00 90.68  ? 816  ALA A O   1 
ATOM   5533 C CB  . ALA A 1 857  ? 132.361 120.315 103.003 1.00 90.68  ? 816  ALA A CB  1 
ATOM   5534 N N   . ILE A 1 858  ? 131.096 123.429 103.523 1.00 84.19  ? 817  ILE A N   1 
ATOM   5535 C CA  . ILE A 1 858  ? 131.239 124.667 104.283 1.00 84.19  ? 817  ILE A CA  1 
ATOM   5536 C C   . ILE A 1 858  ? 129.884 125.100 104.831 1.00 84.19  ? 817  ILE A C   1 
ATOM   5537 O O   . ILE A 1 858  ? 129.650 125.071 106.050 1.00 84.19  ? 817  ILE A O   1 
ATOM   5538 C CB  . ILE A 1 858  ? 131.857 125.786 103.428 1.00 84.19  ? 817  ILE A CB  1 
ATOM   5539 C CG1 . ILE A 1 858  ? 133.230 125.367 102.909 1.00 84.19  ? 817  ILE A CG1 1 
ATOM   5540 C CG2 . ILE A 1 858  ? 131.972 127.065 104.239 1.00 84.19  ? 817  ILE A CG2 1 
ATOM   5541 C CD1 . ILE A 1 858  ? 134.228 125.083 103.990 1.00 84.19  ? 817  ILE A CD1 1 
ATOM   5542 N N   . GLY A 1 859  ? 128.973 125.472 103.931 1.00 79.15  ? 818  GLY A N   1 
ATOM   5543 C CA  . GLY A 1 859  ? 127.723 126.076 104.336 1.00 79.15  ? 818  GLY A CA  1 
ATOM   5544 C C   . GLY A 1 859  ? 126.808 125.153 105.109 1.00 79.15  ? 818  GLY A C   1 
ATOM   5545 O O   . GLY A 1 859  ? 126.340 125.516 106.192 1.00 79.15  ? 818  GLY A O   1 
ATOM   5546 N N   . ASP A 1 860  ? 126.536 123.961 104.570 1.00 83.33  ? 819  ASP A N   1 
ATOM   5547 C CA  . ASP A 1 860  ? 125.624 123.057 105.256 1.00 83.33  ? 819  ASP A CA  1 
ATOM   5548 C C   . ASP A 1 860  ? 126.210 122.624 106.589 1.00 83.33  ? 819  ASP A C   1 
ATOM   5549 O O   . ASP A 1 860  ? 125.493 122.532 107.592 1.00 83.33  ? 819  ASP A O   1 
ATOM   5550 C CB  . ASP A 1 860  ? 125.325 121.845 104.377 1.00 83.33  ? 819  ASP A CB  1 
ATOM   5551 C CG  . ASP A 1 860  ? 124.496 122.201 103.160 1.00 83.33  ? 819  ASP A CG  1 
ATOM   5552 O OD1 . ASP A 1 860  ? 123.709 123.168 103.238 1.00 83.33  ? 819  ASP A OD1 1 
ATOM   5553 O OD2 . ASP A 1 860  ? 124.631 121.513 102.126 1.00 83.33  ? 819  ASP A OD2 1 
ATOM   5554 N N   . ARG A 1 861  ? 127.517 122.363 106.616 1.00 80.60  ? 820  ARG A N   1 
ATOM   5555 C CA  . ARG A 1 861  ? 128.171 121.959 107.853 1.00 80.60  ? 820  ARG A CA  1 
ATOM   5556 C C   . ARG A 1 861  ? 127.979 123.009 108.938 1.00 80.60  ? 820  ARG A C   1 
ATOM   5557 O O   . ARG A 1 861  ? 127.520 122.698 110.043 1.00 80.60  ? 820  ARG A O   1 
ATOM   5558 C CB  . ARG A 1 861  ? 129.659 121.708 107.605 1.00 80.60  ? 820  ARG A CB  1 
ATOM   5559 C CG  . ARG A 1 861  ? 130.423 121.292 108.848 1.00 80.60  ? 820  ARG A CG  1 
ATOM   5560 C CD  . ARG A 1 861  ? 131.921 121.459 108.666 1.00 80.60  ? 820  ARG A CD  1 
ATOM   5561 N NE  . ARG A 1 861  ? 132.456 120.647 107.580 1.00 80.60  ? 820  ARG A NE  1 
ATOM   5562 C CZ  . ARG A 1 861  ? 132.623 119.332 107.634 1.00 80.60  ? 820  ARG A CZ  1 
ATOM   5563 N NH1 . ARG A 1 861  ? 132.308 118.638 108.715 1.00 80.60  ? 820  ARG A NH1 1 
ATOM   5564 N NH2 . ARG A 1 861  ? 133.130 118.700 106.580 1.00 80.60  ? 820  ARG A NH2 1 
ATOM   5565 N N   . ILE A 1 862  ? 128.308 124.269 108.639 1.00 67.54  ? 821  ILE A N   1 
ATOM   5566 C CA  . ILE A 1 862  ? 128.204 125.289 109.681 1.00 67.54  ? 821  ILE A CA  1 
ATOM   5567 C C   . ILE A 1 862  ? 126.745 125.521 110.063 1.00 67.54  ? 821  ILE A C   1 
ATOM   5568 O O   . ILE A 1 862  ? 126.415 125.668 111.250 1.00 67.54  ? 821  ILE A O   1 
ATOM   5569 C CB  . ILE A 1 862  ? 128.910 126.589 109.249 1.00 67.54  ? 821  ILE A CB  1 
ATOM   5570 C CG1 . ILE A 1 862  ? 128.862 127.621 110.376 1.00 67.54  ? 821  ILE A CG1 1 
ATOM   5571 C CG2 . ILE A 1 862  ? 128.311 127.150 107.980 1.00 67.54  ? 821  ILE A CG2 1 
ATOM   5572 C CD1 . ILE A 1 862  ? 129.567 127.174 111.626 1.00 67.54  ? 821  ILE A CD1 1 
ATOM   5573 N N   . SER A 1 863  ? 125.845 125.521 109.077 1.00 61.81  ? 822  SER A N   1 
ATOM   5574 C CA  . SER A 1 863  ? 124.439 125.780 109.355 1.00 61.81  ? 822  SER A CA  1 
ATOM   5575 C C   . SER A 1 863  ? 123.859 124.726 110.289 1.00 61.81  ? 822  SER A C   1 
ATOM   5576 O O   . SER A 1 863  ? 123.177 125.054 111.265 1.00 61.81  ? 822  SER A O   1 
ATOM   5577 C CB  . SER A 1 863  ? 123.651 125.837 108.048 1.00 61.81  ? 822  SER A CB  1 
ATOM   5578 O OG  . SER A 1 863  ? 122.261 125.740 108.294 1.00 61.81  ? 822  SER A OG  1 
ATOM   5579 N N   . VAL A 1 864  ? 124.125 123.448 110.012 1.00 60.41  ? 823  VAL A N   1 
ATOM   5580 C CA  . VAL A 1 864  ? 123.581 122.406 110.877 1.00 60.41  ? 823  VAL A CA  1 
ATOM   5581 C C   . VAL A 1 864  ? 124.276 122.423 112.230 1.00 60.41  ? 823  VAL A C   1 
ATOM   5582 O O   . VAL A 1 864  ? 123.627 122.271 113.270 1.00 60.41  ? 823  VAL A O   1 
ATOM   5583 C CB  . VAL A 1 864  ? 123.661 121.022 110.203 1.00 60.41  ? 823  VAL A CB  1 
ATOM   5584 C CG1 . VAL A 1 864  ? 122.934 121.042 108.869 1.00 60.41  ? 823  VAL A CG1 1 
ATOM   5585 C CG2 . VAL A 1 864  ? 125.095 120.562 110.034 1.00 60.41  ? 823  VAL A CG2 1 
ATOM   5586 N N   . ILE A 1 865  ? 125.593 122.649 112.254 1.00 58.66  ? 824  ILE A N   1 
ATOM   5587 C CA  . ILE A 1 865  ? 126.308 122.584 113.519 1.00 58.66  ? 824  ILE A CA  1 
ATOM   5588 C C   . ILE A 1 865  ? 125.901 123.714 114.448 1.00 58.66  ? 824  ILE A C   1 
ATOM   5589 O O   . ILE A 1 865  ? 126.096 123.609 115.662 1.00 58.66  ? 824  ILE A O   1 
ATOM   5590 C CB  . ILE A 1 865  ? 127.833 122.578 113.289 1.00 58.66  ? 824  ILE A CB  1 
ATOM   5591 C CG1 . ILE A 1 865  ? 128.545 121.923 114.469 1.00 58.66  ? 824  ILE A CG1 1 
ATOM   5592 C CG2 . ILE A 1 865  ? 128.358 123.984 113.124 1.00 58.66  ? 824  ILE A CG2 1 
ATOM   5593 C CD1 . ILE A 1 865  ? 130.007 121.642 114.214 1.00 58.66  ? 824  ILE A CD1 1 
ATOM   5594 N N   . VAL A 1 866  ? 125.342 124.798 113.923 1.00 53.12  ? 825  VAL A N   1 
ATOM   5595 C CA  . VAL A 1 866  ? 124.844 125.878 114.773 1.00 53.12  ? 825  VAL A CA  1 
ATOM   5596 C C   . VAL A 1 866  ? 123.358 125.711 115.091 1.00 53.12  ? 825  VAL A C   1 
ATOM   5597 O O   . VAL A 1 866  ? 122.934 125.918 116.229 1.00 53.12  ? 825  VAL A O   1 
ATOM   5598 C CB  . VAL A 1 866  ? 125.147 127.257 114.143 1.00 53.12  ? 825  VAL A CB  1 
ATOM   5599 C CG1 . VAL A 1 866  ? 124.407 127.452 112.846 1.00 53.12  ? 825  VAL A CG1 1 
ATOM   5600 C CG2 . VAL A 1 866  ? 124.815 128.362 115.116 1.00 53.12  ? 825  VAL A CG2 1 
ATOM   5601 N N   . GLN A 1 867  ? 122.548 125.304 114.109 1.00 52.53  ? 826  GLN A N   1 
ATOM   5602 C CA  . GLN A 1 867  ? 121.117 125.169 114.355 1.00 52.53  ? 826  GLN A CA  1 
ATOM   5603 C C   . GLN A 1 867  ? 120.824 124.022 115.314 1.00 52.53  ? 826  GLN A C   1 
ATOM   5604 O O   . GLN A 1 867  ? 120.017 124.166 116.241 1.00 52.53  ? 826  GLN A O   1 
ATOM   5605 C CB  . GLN A 1 867  ? 120.375 124.973 113.035 1.00 52.53  ? 826  GLN A CB  1 
ATOM   5606 C CG  . GLN A 1 867  ? 119.065 124.232 113.157 1.00 52.53  ? 826  GLN A CG  1 
ATOM   5607 C CD  . GLN A 1 867  ? 118.316 124.170 111.845 1.00 52.53  ? 826  GLN A CD  1 
ATOM   5608 O OE1 . GLN A 1 867  ? 118.921 124.158 110.776 1.00 52.53  ? 826  GLN A OE1 1 
ATOM   5609 N NE2 . GLN A 1 867  ? 116.993 124.129 111.918 1.00 52.53  ? 826  GLN A NE2 1 
ATOM   5610 N N   . ASN A 1 868  ? 121.472 122.873 115.113 1.00 49.96  ? 827  ASN A N   1 
ATOM   5611 C CA  . ASN A 1 868  ? 121.264 121.751 116.017 1.00 49.96  ? 827  ASN A CA  1 
ATOM   5612 C C   . ASN A 1 868  ? 121.855 122.037 117.386 1.00 49.96  ? 827  ASN A C   1 
ATOM   5613 O O   . ASN A 1 868  ? 121.351 121.545 118.399 1.00 49.96  ? 827  ASN A O   1 
ATOM   5614 C CB  . ASN A 1 868  ? 121.869 120.486 115.421 1.00 49.96  ? 827  ASN A CB  1 
ATOM   5615 C CG  . ASN A 1 868  ? 120.905 119.768 114.519 1.00 49.96  ? 827  ASN A CG  1 
ATOM   5616 O OD1 . ASN A 1 868  ? 119.698 119.974 114.595 1.00 49.96  ? 827  ASN A OD1 1 
ATOM   5617 N ND2 . ASN A 1 868  ? 121.432 118.936 113.640 1.00 49.96  ? 827  ASN A ND2 1 
ATOM   5618 N N   . THR A 1 869  ? 122.922 122.831 117.441 1.00 49.73  ? 828  THR A N   1 
ATOM   5619 C CA  . THR A 1 869  ? 123.447 123.257 118.732 1.00 49.73  ? 828  THR A CA  1 
ATOM   5620 C C   . THR A 1 869  ? 122.419 124.086 119.486 1.00 49.73  ? 828  THR A C   1 
ATOM   5621 O O   . THR A 1 869  ? 122.191 123.872 120.680 1.00 49.73  ? 828  THR A O   1 
ATOM   5622 C CB  . THR A 1 869  ? 124.741 124.046 118.544 1.00 49.73  ? 828  THR A CB  1 
ATOM   5623 O OG1 . THR A 1 869  ? 125.772 123.164 118.084 1.00 49.73  ? 828  THR A OG1 1 
ATOM   5624 C CG2 . THR A 1 869  ? 125.171 124.682 119.854 1.00 49.73  ? 828  THR A CG2 1 
ATOM   5625 N N   . ALA A 1 870  ? 121.771 125.027 118.798 1.00 47.58  ? 829  ALA A N   1 
ATOM   5626 C CA  . ALA A 1 870  ? 120.725 125.818 119.441 1.00 47.58  ? 829  ALA A CA  1 
ATOM   5627 C C   . ALA A 1 870  ? 119.571 124.936 119.902 1.00 47.58  ? 829  ALA A C   1 
ATOM   5628 O O   . ALA A 1 870  ? 119.069 125.079 121.025 1.00 47.58  ? 829  ALA A O   1 
ATOM   5629 C CB  . ALA A 1 870  ? 120.226 126.901 118.486 1.00 47.58  ? 829  ALA A CB  1 
ATOM   5630 N N   . LEU A 1 871  ? 119.140 124.010 119.041 1.00 48.50  ? 830  LEU A N   1 
ATOM   5631 C CA  . LEU A 1 871  ? 118.062 123.089 119.392 1.00 48.50  ? 830  LEU A CA  1 
ATOM   5632 C C   . LEU A 1 871  ? 118.394 122.280 120.639 1.00 48.50  ? 830  LEU A C   1 
ATOM   5633 O O   . LEU A 1 871  ? 117.612 122.235 121.598 1.00 48.50  ? 830  LEU A O   1 
ATOM   5634 C CB  . LEU A 1 871  ? 117.791 122.149 118.219 1.00 48.50  ? 830  LEU A CB  1 
ATOM   5635 C CG  . LEU A 1 871  ? 116.678 121.123 118.404 1.00 48.50  ? 830  LEU A CG  1 
ATOM   5636 C CD1 . LEU A 1 871  ? 115.362 121.811 118.604 1.00 48.50  ? 830  LEU A CD1 1 
ATOM   5637 C CD2 . LEU A 1 871  ? 116.617 120.196 117.213 1.00 48.50  ? 830  LEU A CD2 1 
ATOM   5638 N N   . MET A 1 872  ? 119.554 121.626 120.635 1.00 50.34  ? 831  MET A N   1 
ATOM   5639 C CA  . MET A 1 872  ? 119.943 120.783 121.754 1.00 50.34  ? 831  MET A CA  1 
ATOM   5640 C C   . MET A 1 872  ? 120.119 121.608 123.017 1.00 50.34  ? 831  MET A C   1 
ATOM   5641 O O   . MET A 1 872  ? 119.749 121.170 124.108 1.00 50.34  ? 831  MET A O   1 
ATOM   5642 C CB  . MET A 1 872  ? 121.223 120.022 121.416 1.00 50.34  ? 831  MET A CB  1 
ATOM   5643 C CG  . MET A 1 872  ? 121.700 119.085 122.508 1.00 50.34  ? 831  MET A CG  1 
ATOM   5644 S SD  . MET A 1 872  ? 122.466 117.596 121.841 1.00 50.34  ? 831  MET A SD  1 
ATOM   5645 C CE  . MET A 1 872  ? 123.238 116.913 123.306 1.00 50.34  ? 831  MET A CE  1 
ATOM   5646 N N   . LEU A 1 873  ? 120.670 122.816 122.890 1.00 49.06  ? 832  LEU A N   1 
ATOM   5647 C CA  . LEU A 1 873  ? 120.868 123.660 124.061 1.00 49.06  ? 832  LEU A CA  1 
ATOM   5648 C C   . LEU A 1 873  ? 119.538 124.042 124.696 1.00 49.06  ? 832  LEU A C   1 
ATOM   5649 O O   . LEU A 1 873  ? 119.367 123.933 125.915 1.00 49.06  ? 832  LEU A O   1 
ATOM   5650 C CB  . LEU A 1 873  ? 121.661 124.906 123.673 1.00 49.06  ? 832  LEU A CB  1 
ATOM   5651 C CG  . LEU A 1 873  ? 122.061 125.831 124.819 1.00 49.06  ? 832  LEU A CG  1 
ATOM   5652 C CD1 . LEU A 1 873  ? 122.995 125.107 125.772 1.00 49.06  ? 832  LEU A CD1 1 
ATOM   5653 C CD2 . LEU A 1 873  ? 122.710 127.093 124.281 1.00 49.06  ? 832  LEU A CD2 1 
ATOM   5654 N N   . VAL A 1 874  ? 118.574 124.481 123.882 1.00 46.61  ? 833  VAL A N   1 
ATOM   5655 C CA  . VAL A 1 874  ? 117.281 124.880 124.434 1.00 46.61  ? 833  VAL A CA  1 
ATOM   5656 C C   . VAL A 1 874  ? 116.566 123.684 125.053 1.00 46.61  ? 833  VAL A C   1 
ATOM   5657 O O   . VAL A 1 874  ? 116.042 123.765 126.175 1.00 46.61  ? 833  VAL A O   1 
ATOM   5658 C CB  . VAL A 1 874  ? 116.421 125.556 123.353 1.00 46.61  ? 833  VAL A CB  1 
ATOM   5659 C CG1 . VAL A 1 874  ? 115.023 125.811 123.878 1.00 46.61  ? 833  VAL A CG1 1 
ATOM   5660 C CG2 . VAL A 1 874  ? 117.062 126.853 122.914 1.00 46.61  ? 833  VAL A CG2 1 
ATOM   5661 N N   . ALA A 1 875  ? 116.538 122.553 124.344 1.00 45.48  ? 834  ALA A N   1 
ATOM   5662 C CA  . ALA A 1 875  ? 115.860 121.377 124.878 1.00 45.48  ? 834  ALA A CA  1 
ATOM   5663 C C   . ALA A 1 875  ? 116.513 120.905 126.170 1.00 45.48  ? 834  ALA A C   1 
ATOM   5664 O O   . ALA A 1 875  ? 115.824 120.575 127.143 1.00 45.48  ? 834  ALA A O   1 
ATOM   5665 C CB  . ALA A 1 875  ? 115.853 120.260 123.838 1.00 45.48  ? 834  ALA A CB  1 
ATOM   5666 N N   . CYS A 1 876  ? 117.846 120.883 126.205 1.00 48.45  ? 835  CYS A N   1 
ATOM   5667 C CA  . CYS A 1 876  ? 118.557 120.390 127.375 1.00 48.45  ? 835  CYS A CA  1 
ATOM   5668 C C   . CYS A 1 876  ? 118.380 121.322 128.563 1.00 48.45  ? 835  CYS A C   1 
ATOM   5669 O O   . CYS A 1 876  ? 118.229 120.862 129.699 1.00 48.45  ? 835  CYS A O   1 
ATOM   5670 C CB  . CYS A 1 876  ? 120.038 120.208 127.041 1.00 48.45  ? 835  CYS A CB  1 
ATOM   5671 S SG  . CYS A 1 876  ? 121.101 119.964 128.475 1.00 48.45  ? 835  CYS A SG  1 
ATOM   5672 N N   . THR A 1 877  ? 118.387 122.637 128.333 1.00 46.76  ? 836  THR A N   1 
ATOM   5673 C CA  . THR A 1 877  ? 118.202 123.547 129.458 1.00 46.76  ? 836  THR A CA  1 
ATOM   5674 C C   . THR A 1 877  ? 116.781 123.463 130.004 1.00 46.76  ? 836  THR A C   1 
ATOM   5675 O O   . THR A 1 877  ? 116.581 123.484 131.225 1.00 46.76  ? 836  THR A O   1 
ATOM   5676 C CB  . THR A 1 877  ? 118.573 124.986 129.074 1.00 46.76  ? 836  THR A CB  1 
ATOM   5677 O OG1 . THR A 1 877  ? 118.598 125.797 130.253 1.00 46.76  ? 836  THR A OG1 1 
ATOM   5678 C CG2 . THR A 1 877  ? 117.589 125.589 128.096 1.00 46.76  ? 836  THR A CG2 1 
ATOM   5679 N N   . ALA A 1 878  ? 115.781 123.327 129.127 1.00 44.63  ? 837  ALA A N   1 
ATOM   5680 C CA  . ALA A 1 878  ? 114.415 123.155 129.614 1.00 44.63  ? 837  ALA A CA  1 
ATOM   5681 C C   . ALA A 1 878  ? 114.283 121.866 130.415 1.00 44.63  ? 837  ALA A C   1 
ATOM   5682 O O   . ALA A 1 878  ? 113.717 121.856 131.518 1.00 44.63  ? 837  ALA A O   1 
ATOM   5683 C CB  . ALA A 1 878  ? 113.432 123.167 128.446 1.00 44.63  ? 837  ALA A CB  1 
ATOM   5684 N N   . GLY A 1 879  ? 114.830 120.770 129.886 1.00 43.41  ? 838  GLY A N   1 
ATOM   5685 C CA  . GLY A 1 879  ? 114.755 119.503 130.591 1.00 43.41  ? 838  GLY A CA  1 
ATOM   5686 C C   . GLY A 1 879  ? 115.464 119.542 131.929 1.00 43.41  ? 838  GLY A C   1 
ATOM   5687 O O   . GLY A 1 879  ? 114.976 118.993 132.918 1.00 43.41  ? 838  GLY A O   1 
ATOM   5688 N N   . PHE A 1 880  ? 116.631 120.186 131.976 1.00 45.44  ? 839  PHE A N   1 
ATOM   5689 C CA  . PHE A 1 880  ? 117.367 120.268 133.230 1.00 45.44  ? 839  PHE A CA  1 
ATOM   5690 C C   . PHE A 1 880  ? 116.607 121.084 134.260 1.00 45.44  ? 839  PHE A C   1 
ATOM   5691 O O   . PHE A 1 880  ? 116.395 120.611 135.384 1.00 45.44  ? 839  PHE A O   1 
ATOM   5692 C CB  . PHE A 1 880  ? 118.758 120.849 132.999 1.00 45.44  ? 839  PHE A CB  1 
ATOM   5693 C CG  . PHE A 1 880  ? 119.815 119.807 132.796 1.00 45.44  ? 839  PHE A CG  1 
ATOM   5694 C CD1 . PHE A 1 880  ? 119.814 119.011 131.666 1.00 45.44  ? 839  PHE A CD1 1 
ATOM   5695 C CD2 . PHE A 1 880  ? 120.795 119.604 133.750 1.00 45.44  ? 839  PHE A CD2 1 
ATOM   5696 C CE1 . PHE A 1 880  ? 120.779 118.049 131.480 1.00 45.44  ? 839  PHE A CE1 1 
ATOM   5697 C CE2 . PHE A 1 880  ? 121.762 118.640 133.570 1.00 45.44  ? 839  PHE A CE2 1 
ATOM   5698 C CZ  . PHE A 1 880  ? 121.754 117.862 132.433 1.00 45.44  ? 839  PHE A CZ  1 
ATOM   5699 N N   . VAL A 1 881  ? 116.128 122.270 133.871 1.00 42.46  ? 840  VAL A N   1 
ATOM   5700 C CA  . VAL A 1 881  ? 115.391 123.130 134.791 1.00 42.46  ? 840  VAL A CA  1 
ATOM   5701 C C   . VAL A 1 881  ? 114.166 122.411 135.335 1.00 42.46  ? 840  VAL A C   1 
ATOM   5702 O O   . VAL A 1 881  ? 113.829 122.541 136.518 1.00 42.46  ? 840  VAL A O   1 
ATOM   5703 C CB  . VAL A 1 881  ? 115.014 124.450 134.094 1.00 42.46  ? 840  VAL A CB  1 
ATOM   5704 C CG1 . VAL A 1 881  ? 114.004 125.222 134.919 1.00 42.46  ? 840  VAL A CG1 1 
ATOM   5705 C CG2 . VAL A 1 881  ? 116.253 125.288 133.860 1.00 42.46  ? 840  VAL A CG2 1 
ATOM   5706 N N   . LEU A 1 882  ? 113.481 121.636 134.493 1.00 42.77  ? 841  LEU A N   1 
ATOM   5707 C CA  . LEU A 1 882  ? 112.317 120.905 134.985 1.00 42.77  ? 841  LEU A CA  1 
ATOM   5708 C C   . LEU A 1 882  ? 112.729 119.764 135.913 1.00 42.77  ? 841  LEU A C   1 
ATOM   5709 O O   . LEU A 1 882  ? 112.362 119.752 137.093 1.00 42.77  ? 841  LEU A O   1 
ATOM   5710 C CB  . LEU A 1 882  ? 111.484 120.400 133.812 1.00 42.77  ? 841  LEU A CB  1 
ATOM   5711 C CG  . LEU A 1 882  ? 110.811 121.513 133.015 1.00 42.77  ? 841  LEU A CG  1 
ATOM   5712 C CD1 . LEU A 1 882  ? 109.923 120.941 131.940 1.00 42.77  ? 841  LEU A CD1 1 
ATOM   5713 C CD2 . LEU A 1 882  ? 110.011 122.399 133.946 1.00 42.77  ? 841  LEU A CD2 1 
ATOM   5714 N N   . GLN A 1 883  ? 113.490 118.793 135.407 1.00 46.34  ? 842  GLN A N   1 
ATOM   5715 C CA  . GLN A 1 883  ? 113.963 117.697 136.261 1.00 46.34  ? 842  GLN A CA  1 
ATOM   5716 C C   . GLN A 1 883  ? 115.329 117.243 135.730 1.00 46.34  ? 842  GLN A C   1 
ATOM   5717 O O   . GLN A 1 883  ? 115.404 116.395 134.840 1.00 46.34  ? 842  GLN A O   1 
ATOM   5718 C CB  . GLN A 1 883  ? 112.973 116.553 136.295 1.00 46.34  ? 842  GLN A CB  1 
ATOM   5719 C CG  . GLN A 1 883  ? 113.414 115.361 137.121 1.00 46.34  ? 842  GLN A CG  1 
ATOM   5720 C CD  . GLN A 1 883  ? 113.694 115.722 138.562 1.00 46.34  ? 842  GLN A CD  1 
ATOM   5721 O OE1 . GLN A 1 883  ? 112.781 116.024 139.326 1.00 46.34  ? 842  GLN A OE1 1 
ATOM   5722 N NE2 . GLN A 1 883  ? 114.961 115.680 138.946 1.00 46.34  ? 842  GLN A NE2 1 
ATOM   5723 N N   . TRP A 1 884  ? 116.392 117.822 136.298 1.00 50.10  ? 843  TRP A N   1 
ATOM   5724 C CA  . TRP A 1 884  ? 117.743 117.540 135.820 1.00 50.10  ? 843  TRP A CA  1 
ATOM   5725 C C   . TRP A 1 884  ? 118.081 116.053 135.841 1.00 50.10  ? 843  TRP A C   1 
ATOM   5726 O O   . TRP A 1 884  ? 118.837 115.581 134.989 1.00 50.10  ? 843  TRP A O   1 
ATOM   5727 C CB  . TRP A 1 884  ? 118.767 118.314 136.646 1.00 50.10  ? 843  TRP A CB  1 
ATOM   5728 C CG  . TRP A 1 884  ? 118.795 117.930 138.081 1.00 50.10  ? 843  TRP A CG  1 
ATOM   5729 C CD1 . TRP A 1 884  ? 117.990 118.399 139.072 1.00 50.10  ? 843  TRP A CD1 1 
ATOM   5730 C CD2 . TRP A 1 884  ? 119.659 116.966 138.686 1.00 50.10  ? 843  TRP A CD2 1 
ATOM   5731 N NE1 . TRP A 1 884  ? 118.313 117.802 140.264 1.00 50.10  ? 843  TRP A NE1 1 
ATOM   5732 C CE2 . TRP A 1 884  ? 119.334 116.915 140.051 1.00 50.10  ? 843  TRP A CE2 1 
ATOM   5733 C CE3 . TRP A 1 884  ? 120.680 116.147 138.206 1.00 50.10  ? 843  TRP A CE3 1 
ATOM   5734 C CZ2 . TRP A 1 884  ? 119.994 116.078 140.941 1.00 50.10  ? 843  TRP A CZ2 1 
ATOM   5735 C CZ3 . TRP A 1 884  ? 121.333 115.316 139.090 1.00 50.10  ? 843  TRP A CZ3 1 
ATOM   5736 C CH2 . TRP A 1 884  ? 120.988 115.287 140.442 1.00 50.10  ? 843  TRP A CH2 1 
ATOM   5737 N N   . ARG A 1 885  ? 117.560 115.301 136.808 1.00 47.33  ? 844  ARG A N   1 
ATOM   5738 C CA  . ARG A 1 885  ? 117.916 113.886 136.901 1.00 47.33  ? 844  ARG A CA  1 
ATOM   5739 C C   . ARG A 1 885  ? 117.442 113.115 135.672 1.00 47.33  ? 844  ARG A C   1 
ATOM   5740 O O   . ARG A 1 885  ? 118.228 112.430 134.998 1.00 47.33  ? 844  ARG A O   1 
ATOM   5741 C CB  . ARG A 1 885  ? 117.321 113.291 138.175 1.00 47.33  ? 844  ARG A CB  1 
ATOM   5742 C CG  . ARG A 1 885  ? 117.937 111.981 138.611 1.00 47.33  ? 844  ARG A CG  1 
ATOM   5743 C CD  . ARG A 1 885  ? 117.549 111.653 140.045 1.00 47.33  ? 844  ARG A CD  1 
ATOM   5744 N NE  . ARG A 1 885  ? 118.277 112.441 141.032 1.00 47.33  ? 844  ARG A NE  1 
ATOM   5745 C CZ  . ARG A 1 885  ? 117.738 113.398 141.773 1.00 47.33  ? 844  ARG A CZ  1 
ATOM   5746 N NH1 . ARG A 1 885  ? 116.480 113.771 141.611 1.00 47.33  ? 844  ARG A NH1 1 
ATOM   5747 N NH2 . ARG A 1 885  ? 118.479 113.999 142.699 1.00 47.33  ? 844  ARG A NH2 1 
ATOM   5748 N N   . LEU A 1 886  ? 116.153 113.236 135.351 1.00 45.78  ? 845  LEU A N   1 
ATOM   5749 C CA  . LEU A 1 886  ? 115.624 112.580 134.164 1.00 45.78  ? 845  LEU A CA  1 
ATOM   5750 C C   . LEU A 1 886  ? 116.234 113.167 132.901 1.00 45.78  ? 845  LEU A C   1 
ATOM   5751 O O   . LEU A 1 886  ? 116.450 112.450 131.920 1.00 45.78  ? 845  LEU A O   1 
ATOM   5752 C CB  . LEU A 1 886  ? 114.102 112.697 134.132 1.00 45.78  ? 845  LEU A CB  1 
ATOM   5753 C CG  . LEU A 1 886  ? 113.406 111.989 132.974 1.00 45.78  ? 845  LEU A CG  1 
ATOM   5754 C CD1 . LEU A 1 886  ? 113.518 110.491 133.132 1.00 45.78  ? 845  LEU A CD1 1 
ATOM   5755 C CD2 . LEU A 1 886  ? 111.955 112.408 132.896 1.00 45.78  ? 845  LEU A CD2 1 
ATOM   5756 N N   . ALA A 1 887  ? 116.524 114.470 132.906 1.00 43.68  ? 846  ALA A N   1 
ATOM   5757 C CA  . ALA A 1 887  ? 117.143 115.077 131.734 1.00 43.68  ? 846  ALA A CA  1 
ATOM   5758 C C   . ALA A 1 887  ? 118.515 114.476 131.463 1.00 43.68  ? 846  ALA A C   1 
ATOM   5759 O O   . ALA A 1 887  ? 118.867 114.211 130.310 1.00 43.68  ? 846  ALA A O   1 
ATOM   5760 C CB  . ALA A 1 887  ? 117.246 116.587 131.919 1.00 43.68  ? 846  ALA A CB  1 
ATOM   5761 N N   . LEU A 1 888  ? 119.301 114.258 132.514 1.00 44.09  ? 847  LEU A N   1 
ATOM   5762 C CA  . LEU A 1 888  ? 120.618 113.656 132.352 1.00 44.09  ? 847  LEU A CA  1 
ATOM   5763 C C   . LEU A 1 888  ? 120.498 112.218 131.871 1.00 44.09  ? 847  LEU A C   1 
ATOM   5764 O O   . LEU A 1 888  ? 121.225 111.787 130.965 1.00 44.09  ? 847  LEU A O   1 
ATOM   5765 C CB  . LEU A 1 888  ? 121.379 113.739 133.677 1.00 44.09  ? 847  LEU A CB  1 
ATOM   5766 C CG  . LEU A 1 888  ? 122.853 113.348 133.762 1.00 44.09  ? 847  LEU A CG  1 
ATOM   5767 C CD1 . LEU A 1 888  ? 123.505 114.120 134.887 1.00 44.09  ? 847  LEU A CD1 1 
ATOM   5768 C CD2 . LEU A 1 888  ? 123.018 111.856 133.997 1.00 44.09  ? 847  LEU A CD2 1 
ATOM   5769 N N   . VAL A 1 889  ? 119.564 111.461 132.452 1.00 43.04  ? 848  VAL A N   1 
ATOM   5770 C CA  . VAL A 1 889  ? 119.370 110.089 131.992 1.00 43.04  ? 848  VAL A CA  1 
ATOM   5771 C C   . VAL A 1 889  ? 118.976 110.059 130.520 1.00 43.04  ? 848  VAL A C   1 
ATOM   5772 O O   . VAL A 1 889  ? 119.434 109.196 129.766 1.00 43.04  ? 848  VAL A O   1 
ATOM   5773 C CB  . VAL A 1 889  ? 118.331 109.368 132.866 1.00 43.04  ? 848  VAL A CB  1 
ATOM   5774 C CG1 . VAL A 1 889  ? 117.966 108.029 132.254 1.00 43.04  ? 848  VAL A CG1 1 
ATOM   5775 C CG2 . VAL A 1 889  ? 118.878 109.176 134.264 1.00 43.04  ? 848  VAL A CG2 1 
ATOM   5776 N N   . LEU A 1 890  ? 118.137 110.998 130.082 1.00 41.12  ? 849  LEU A N   1 
ATOM   5777 C CA  . LEU A 1 890  ? 117.700 111.003 128.691 1.00 41.12  ? 849  LEU A CA  1 
ATOM   5778 C C   . LEU A 1 890  ? 118.817 111.435 127.749 1.00 41.12  ? 849  LEU A C   1 
ATOM   5779 O O   . LEU A 1 890  ? 118.990 110.842 126.679 1.00 41.12  ? 849  LEU A O   1 
ATOM   5780 C CB  . LEU A 1 890  ? 116.479 111.903 128.527 1.00 41.12  ? 849  LEU A CB  1 
ATOM   5781 C CG  . LEU A 1 890  ? 115.149 111.156 128.455 1.00 41.12  ? 849  LEU A CG  1 
ATOM   5782 C CD1 . LEU A 1 890  ? 114.905 110.376 129.725 1.00 41.12  ? 849  LEU A CD1 1 
ATOM   5783 C CD2 . LEU A 1 890  ? 114.021 112.124 128.212 1.00 41.12  ? 849  LEU A CD2 1 
ATOM   5784 N N   . VAL A 1 891  ? 119.587 112.462 128.118 1.00 42.80  ? 850  VAL A N   1 
ATOM   5785 C CA  . VAL A 1 891  ? 120.677 112.882 127.246 1.00 42.80  ? 850  VAL A CA  1 
ATOM   5786 C C   . VAL A 1 891  ? 121.804 111.862 127.242 1.00 42.80  ? 850  VAL A C   1 
ATOM   5787 O O   . VAL A 1 891  ? 122.699 111.943 126.396 1.00 42.80  ? 850  VAL A O   1 
ATOM   5788 C CB  . VAL A 1 891  ? 121.221 114.271 127.626 1.00 42.80  ? 850  VAL A CB  1 
ATOM   5789 C CG1 . VAL A 1 891  ? 120.106 115.298 127.623 1.00 42.80  ? 850  VAL A CG1 1 
ATOM   5790 C CG2 . VAL A 1 891  ? 121.925 114.225 128.963 1.00 42.80  ? 850  VAL A CG2 1 
ATOM   5791 N N   . ALA A 1 892  ? 121.794 110.906 128.172 1.00 43.01  ? 851  ALA A N   1 
ATOM   5792 C CA  . ALA A 1 892  ? 122.701 109.771 128.035 1.00 43.01  ? 851  ALA A CA  1 
ATOM   5793 C C   . ALA A 1 892  ? 122.398 108.974 126.772 1.00 43.01  ? 851  ALA A C   1 
ATOM   5794 O O   . ALA A 1 892  ? 123.317 108.533 126.074 1.00 43.01  ? 851  ALA A O   1 
ATOM   5795 C CB  . ALA A 1 892  ? 122.620 108.873 129.267 1.00 43.01  ? 851  ALA A CB  1 
ATOM   5796 N N   . VAL A 1 893  ? 121.114 108.782 126.457 1.00 44.22  ? 852  VAL A N   1 
ATOM   5797 C CA  . VAL A 1 893  ? 120.706 108.005 125.293 1.00 44.22  ? 852  VAL A CA  1 
ATOM   5798 C C   . VAL A 1 893  ? 120.240 108.878 124.139 1.00 44.22  ? 852  VAL A C   1 
ATOM   5799 O O   . VAL A 1 893  ? 119.652 108.361 123.181 1.00 44.22  ? 852  VAL A O   1 
ATOM   5800 C CB  . VAL A 1 893  ? 119.605 106.993 125.662 1.00 44.22  ? 852  VAL A CB  1 
ATOM   5801 C CG1 . VAL A 1 893  ? 120.078 106.080 126.777 1.00 44.22  ? 852  VAL A CG1 1 
ATOM   5802 C CG2 . VAL A 1 893  ? 118.330 107.714 126.061 1.00 44.22  ? 852  VAL A CG2 1 
ATOM   5803 N N   . PHE A 1 894  ? 120.475 110.186 124.204 1.00 44.04  ? 853  PHE A N   1 
ATOM   5804 C CA  . PHE A 1 894  ? 120.071 111.082 123.121 1.00 44.04  ? 853  PHE A CA  1 
ATOM   5805 C C   . PHE A 1 894  ? 120.713 110.726 121.784 1.00 44.04  ? 853  PHE A C   1 
ATOM   5806 O O   . PHE A 1 894  ? 119.994 110.698 120.766 1.00 44.04  ? 853  PHE A O   1 
ATOM   5807 C CB  . PHE A 1 894  ? 120.384 112.523 123.539 1.00 44.04  ? 853  PHE A CB  1 
ATOM   5808 C CG  . PHE A 1 894  ? 119.772 113.568 122.658 1.00 44.04  ? 853  PHE A CG  1 
ATOM   5809 C CD1 . PHE A 1 894  ? 118.475 113.995 122.872 1.00 44.04  ? 853  PHE A CD1 1 
ATOM   5810 C CD2 . PHE A 1 894  ? 120.500 114.145 121.635 1.00 44.04  ? 853  PHE A CD2 1 
ATOM   5811 C CE1 . PHE A 1 894  ? 117.914 114.969 122.075 1.00 44.04  ? 853  PHE A CE1 1 
ATOM   5812 C CE2 . PHE A 1 894  ? 119.941 115.118 120.833 1.00 44.04  ? 853  PHE A CE2 1 
ATOM   5813 C CZ  . PHE A 1 894  ? 118.646 115.528 121.053 1.00 44.04  ? 853  PHE A CZ  1 
ATOM   5814 N N   . PRO A 1 895  ? 122.024 110.457 121.695 1.00 45.50  ? 854  PRO A N   1 
ATOM   5815 C CA  . PRO A 1 895  ? 122.592 110.071 120.393 1.00 45.50  ? 854  PRO A CA  1 
ATOM   5816 C C   . PRO A 1 895  ? 121.964 108.824 119.798 1.00 45.50  ? 854  PRO A C   1 
ATOM   5817 O O   . PRO A 1 895  ? 121.841 108.726 118.575 1.00 45.50  ? 854  PRO A O   1 
ATOM   5818 C CB  . PRO A 1 895  ? 124.077 109.867 120.716 1.00 45.50  ? 854  PRO A CB  1 
ATOM   5819 C CG  . PRO A 1 895  ? 124.321 110.706 121.899 1.00 45.50  ? 854  PRO A CG  1 
ATOM   5820 C CD  . PRO A 1 895  ? 123.080 110.601 122.713 1.00 45.50  ? 854  PRO A CD  1 
ATOM   5821 N N   . VAL A 1 896  ? 121.569 107.862 120.632 1.00 45.15  ? 855  VAL A N   1 
ATOM   5822 C CA  . VAL A 1 896  ? 120.939 106.649 120.117 1.00 45.15  ? 855  VAL A CA  1 
ATOM   5823 C C   . VAL A 1 896  ? 119.623 106.987 119.429 1.00 45.15  ? 855  VAL A C   1 
ATOM   5824 O O   . VAL A 1 896  ? 119.326 106.491 118.336 1.00 45.15  ? 855  VAL A O   1 
ATOM   5825 C CB  . VAL A 1 896  ? 120.739 105.628 121.250 1.00 45.15  ? 855  VAL A CB  1 
ATOM   5826 C CG1 . VAL A 1 896  ? 120.010 104.408 120.736 1.00 45.15  ? 855  VAL A CG1 1 
ATOM   5827 C CG2 . VAL A 1 896  ? 122.076 105.237 121.845 1.00 45.15  ? 855  VAL A CG2 1 
ATOM   5828 N N   . VAL A 1 897  ? 118.819 107.847 120.057 1.00 44.87  ? 856  VAL A N   1 
ATOM   5829 C CA  . VAL A 1 897  ? 117.546 108.254 119.467 1.00 44.87  ? 856  VAL A CA  1 
ATOM   5830 C C   . VAL A 1 897  ? 117.778 108.995 118.158 1.00 44.87  ? 856  VAL A C   1 
ATOM   5831 O O   . VAL A 1 897  ? 117.093 108.756 117.153 1.00 44.87  ? 856  VAL A O   1 
ATOM   5832 C CB  . VAL A 1 897  ? 116.747 109.111 120.466 1.00 44.87  ? 856  VAL A CB  1 
ATOM   5833 C CG1 . VAL A 1 897  ? 115.458 109.596 119.839 1.00 44.87  ? 856  VAL A CG1 1 
ATOM   5834 C CG2 . VAL A 1 897  ? 116.466 108.321 121.726 1.00 44.87  ? 856  VAL A CG2 1 
ATOM   5835 N N   . VAL A 1 898  ? 118.750 109.911 118.151 1.00 46.73  ? 857  VAL A N   1 
ATOM   5836 C CA  . VAL A 1 898  ? 119.026 110.678 116.938 1.00 46.73  ? 857  VAL A CA  1 
ATOM   5837 C C   . VAL A 1 898  ? 119.470 109.753 115.813 1.00 46.73  ? 857  VAL A C   1 
ATOM   5838 O O   . VAL A 1 898  ? 119.014 109.872 114.668 1.00 46.73  ? 857  VAL A O   1 
ATOM   5839 C CB  . VAL A 1 898  ? 120.071 111.771 117.218 1.00 46.73  ? 857  VAL A CB  1 
ATOM   5840 C CG1 . VAL A 1 898  ? 120.395 112.524 115.945 1.00 46.73  ? 857  VAL A CG1 1 
ATOM   5841 C CG2 . VAL A 1 898  ? 119.555 112.722 118.269 1.00 46.73  ? 857  VAL A CG2 1 
ATOM   5842 N N   . ALA A 1 899  ? 120.364 108.812 116.122 1.00 46.28  ? 858  ALA A N   1 
ATOM   5843 C CA  . ALA A 1 899  ? 120.851 107.880 115.113 1.00 46.28  ? 858  ALA A CA  1 
ATOM   5844 C C   . ALA A 1 899  ? 119.723 107.011 114.578 1.00 46.28  ? 858  ALA A C   1 
ATOM   5845 O O   . ALA A 1 899  ? 119.642 106.753 113.373 1.00 46.28  ? 858  ALA A O   1 
ATOM   5846 C CB  . ALA A 1 899  ? 121.966 107.014 115.698 1.00 46.28  ? 858  ALA A CB  1 
ATOM   5847 N N   . ALA A 1 900  ? 118.843 106.542 115.463 1.00 45.33  ? 859  ALA A N   1 
ATOM   5848 C CA  . ALA A 1 900  ? 117.734 105.707 115.021 1.00 45.33  ? 859  ALA A CA  1 
ATOM   5849 C C   . ALA A 1 900  ? 116.803 106.472 114.091 1.00 45.33  ? 859  ALA A C   1 
ATOM   5850 O O   . ALA A 1 900  ? 116.343 105.930 113.081 1.00 45.33  ? 859  ALA A O   1 
ATOM   5851 C CB  . ALA A 1 900  ? 116.971 105.169 116.225 1.00 45.33  ? 859  ALA A CB  1 
ATOM   5852 N N   . THR A 1 901  ? 116.517 107.737 114.405 1.00 46.67  ? 860  THR A N   1 
ATOM   5853 C CA  . THR A 1 901  ? 115.639 108.511 113.527 1.00 46.67  ? 860  THR A CA  1 
ATOM   5854 C C   . THR A 1 901  ? 116.316 108.815 112.191 1.00 46.67  ? 860  THR A C   1 
ATOM   5855 O O   . THR A 1 901  ? 115.665 108.812 111.133 1.00 46.67  ? 860  THR A O   1 
ATOM   5856 C CB  . THR A 1 901  ? 115.204 109.795 114.225 1.00 46.67  ? 860  THR A CB  1 
ATOM   5857 O OG1 . THR A 1 901  ? 114.858 109.506 115.584 1.00 46.67  ? 860  THR A OG1 1 
ATOM   5858 C CG2 . THR A 1 901  ? 114.003 110.394 113.523 1.00 46.67  ? 860  THR A CG2 1 
ATOM   5859 N N   . VAL A 1 902  ? 117.625 109.070 112.215 1.00 47.56  ? 861  VAL A N   1 
ATOM   5860 C CA  . VAL A 1 902  ? 118.366 109.268 110.972 1.00 47.56  ? 861  VAL A CA  1 
ATOM   5861 C C   . VAL A 1 902  ? 118.291 108.013 110.110 1.00 47.56  ? 861  VAL A C   1 
ATOM   5862 O O   . VAL A 1 902  ? 118.093 108.081 108.892 1.00 47.56  ? 861  VAL A O   1 
ATOM   5863 C CB  . VAL A 1 902  ? 119.821 109.664 111.274 1.00 47.56  ? 861  VAL A CB  1 
ATOM   5864 C CG1 . VAL A 1 902  ? 120.694 109.453 110.055 1.00 47.56  ? 861  VAL A CG1 1 
ATOM   5865 C CG2 . VAL A 1 902  ? 119.888 111.107 111.730 1.00 47.56  ? 861  VAL A CG2 1 
ATOM   5866 N N   . LEU A 1 903  ? 118.448 106.844 110.736 1.00 48.08  ? 862  LEU A N   1 
ATOM   5867 C CA  . LEU A 1 903  ? 118.339 105.590 109.999 1.00 48.08  ? 862  LEU A CA  1 
ATOM   5868 C C   . LEU A 1 903  ? 116.925 105.373 109.479 1.00 48.08  ? 862  LEU A C   1 
ATOM   5869 O O   . LEU A 1 903  ? 116.737 104.761 108.427 1.00 48.08  ? 862  LEU A O   1 
ATOM   5870 C CB  . LEU A 1 903  ? 118.772 104.422 110.880 1.00 48.08  ? 862  LEU A CB  1 
ATOM   5871 C CG  . LEU A 1 903  ? 120.217 103.961 110.714 1.00 48.08  ? 862  LEU A CG  1 
ATOM   5872 C CD1 . LEU A 1 903  ? 121.187 105.052 111.121 1.00 48.08  ? 862  LEU A CD1 1 
ATOM   5873 C CD2 . LEU A 1 903  ? 120.460 102.710 111.531 1.00 48.08  ? 862  LEU A CD2 1 
ATOM   5874 N N   . GLN A 1 904  ? 115.918 105.857 110.205 1.00 46.61  ? 863  GLN A N   1 
ATOM   5875 C CA  . GLN A 1 904  ? 114.554 105.796 109.688 1.00 46.61  ? 863  GLN A CA  1 
ATOM   5876 C C   . GLN A 1 904  ? 114.423 106.591 108.396 1.00 46.61  ? 863  GLN A C   1 
ATOM   5877 O O   . GLN A 1 904  ? 113.830 106.118 107.417 1.00 46.61  ? 863  GLN A O   1 
ATOM   5878 C CB  . GLN A 1 904  ? 113.569 106.319 110.732 1.00 46.61  ? 863  GLN A CB  1 
ATOM   5879 C CG  . GLN A 1 904  ? 113.424 105.437 111.951 1.00 46.61  ? 863  GLN A CG  1 
ATOM   5880 C CD  . GLN A 1 904  ? 112.405 105.971 112.928 1.00 46.61  ? 863  GLN A CD  1 
ATOM   5881 O OE1 . GLN A 1 904  ? 112.715 106.223 114.089 1.00 46.61  ? 863  GLN A OE1 1 
ATOM   5882 N NE2 . GLN A 1 904  ? 111.177 106.151 112.462 1.00 46.61  ? 863  GLN A NE2 1 
ATOM   5883 N N   . LYS A 1 905  ? 114.983 107.800 108.371 1.00 52.51  ? 864  LYS A N   1 
ATOM   5884 C CA  . LYS A 1 905  ? 114.943 108.592 107.141 1.00 52.51  ? 864  LYS A CA  1 
ATOM   5885 C C   . LYS A 1 905  ? 115.729 107.918 106.016 1.00 52.51  ? 864  LYS A C   1 
ATOM   5886 O O   . LYS A 1 905  ? 115.289 107.901 104.857 1.00 52.51  ? 864  LYS A O   1 
ATOM   5887 C CB  . LYS A 1 905  ? 115.469 109.999 107.406 1.00 52.51  ? 864  LYS A CB  1 
ATOM   5888 C CG  . LYS A 1 905  ? 114.372 111.018 107.652 1.00 52.51  ? 864  LYS A CG  1 
ATOM   5889 C CD  . LYS A 1 905  ? 114.034 111.130 109.128 1.00 52.51  ? 864  LYS A CD  1 
ATOM   5890 C CE  . LYS A 1 905  ? 113.081 112.282 109.383 1.00 52.51  ? 864  LYS A CE  1 
ATOM   5891 N NZ  . LYS A 1 905  ? 112.798 112.456 110.832 1.00 52.51  ? 864  LYS A NZ  1 
ATOM   5892 N N   . MET A 1 906  ? 116.891 107.348 106.341 1.00 52.38  ? 865  MET A N   1 
ATOM   5893 C CA  . MET A 1 906  ? 117.673 106.642 105.330 1.00 52.38  ? 865  MET A CA  1 
ATOM   5894 C C   . MET A 1 906  ? 116.899 105.456 104.767 1.00 52.38  ? 865  MET A C   1 
ATOM   5895 O O   . MET A 1 906  ? 116.944 105.192 103.561 1.00 52.38  ? 865  MET A O   1 
ATOM   5896 C CB  . MET A 1 906  ? 119.006 106.186 105.919 1.00 52.38  ? 865  MET A CB  1 
ATOM   5897 C CG  . MET A 1 906  ? 120.007 107.313 106.114 1.00 52.38  ? 865  MET A CG  1 
ATOM   5898 S SD  . MET A 1 906  ? 121.487 106.784 106.991 1.00 52.38  ? 865  MET A SD  1 
ATOM   5899 C CE  . MET A 1 906  ? 121.878 105.279 106.108 1.00 52.38  ? 865  MET A CE  1 
ATOM   5900 N N   . PHE A 1 907  ? 116.183 104.729 105.629 1.00 52.28  ? 866  PHE A N   1 
ATOM   5901 C CA  . PHE A 1 907  ? 115.291 103.673 105.166 1.00 52.28  ? 866  PHE A CA  1 
ATOM   5902 C C   . PHE A 1 907  ? 114.249 104.227 104.215 1.00 52.28  ? 866  PHE A C   1 
ATOM   5903 O O   . PHE A 1 907  ? 113.938 103.611 103.190 1.00 52.28  ? 866  PHE A O   1 
ATOM   5904 C CB  . PHE A 1 907  ? 114.608 103.006 106.358 1.00 52.28  ? 866  PHE A CB  1 
ATOM   5905 C CG  . PHE A 1 907  ? 113.547 102.015 105.974 1.00 52.28  ? 866  PHE A CG  1 
ATOM   5906 C CD1 . PHE A 1 907  ? 113.887 100.755 105.524 1.00 52.28  ? 866  PHE A CD1 1 
ATOM   5907 C CD2 . PHE A 1 907  ? 112.209 102.355 106.043 1.00 52.28  ? 866  PHE A CD2 1 
ATOM   5908 C CE1 . PHE A 1 907  ? 112.914 99.847  105.171 1.00 52.28  ? 866  PHE A CE1 1 
ATOM   5909 C CE2 . PHE A 1 907  ? 111.234 101.452 105.684 1.00 52.28  ? 866  PHE A CE2 1 
ATOM   5910 C CZ  . PHE A 1 907  ? 111.587 100.197 105.248 1.00 52.28  ? 866  PHE A CZ  1 
ATOM   5911 N N   . MET A 1 908  ? 113.686 105.387 104.551 1.00 57.51  ? 867  MET A N   1 
ATOM   5912 C CA  . MET A 1 908  ? 112.757 106.045 103.640 1.00 57.51  ? 867  MET A CA  1 
ATOM   5913 C C   . MET A 1 908  ? 113.386 106.234 102.265 1.00 57.51  ? 867  MET A C   1 
ATOM   5914 O O   . MET A 1 908  ? 112.728 106.025 101.240 1.00 57.51  ? 867  MET A O   1 
ATOM   5915 C CB  . MET A 1 908  ? 112.308 107.385 104.223 1.00 57.51  ? 867  MET A CB  1 
ATOM   5916 C CG  . MET A 1 908  ? 111.509 108.250 103.270 1.00 57.51  ? 867  MET A CG  1 
ATOM   5917 S SD  . MET A 1 908  ? 111.155 109.882 103.951 1.00 57.51  ? 867  MET A SD  1 
ATOM   5918 C CE  . MET A 1 908  ? 111.026 109.505 105.695 1.00 57.51  ? 867  MET A CE  1 
ATOM   5919 N N   . THR A 1 909  ? 114.667 106.617 102.220 1.00 60.73  ? 868  THR A N   1 
ATOM   5920 C CA  . THR A 1 909  ? 115.336 106.739 100.925 1.00 60.73  ? 868  THR A CA  1 
ATOM   5921 C C   . THR A 1 909  ? 115.661 105.373 100.327 1.00 60.73  ? 868  THR A C   1 
ATOM   5922 O O   . THR A 1 909  ? 115.474 105.158 99.125  1.00 60.73  ? 868  THR A O   1 
ATOM   5923 C CB  . THR A 1 909  ? 116.613 107.572 101.046 1.00 60.73  ? 868  THR A CB  1 
ATOM   5924 O OG1 . THR A 1 909  ? 117.657 106.772 101.615 1.00 60.73  ? 868  THR A OG1 1 
ATOM   5925 C CG2 . THR A 1 909  ? 116.375 108.795 101.918 1.00 60.73  ? 868  THR A CG2 1 
ATOM   5926 N N   . GLY A 1 910  ? 116.154 104.441 101.141 1.00 55.58  ? 869  GLY A N   1 
ATOM   5927 C CA  . GLY A 1 910  ? 116.530 103.126 100.653 1.00 55.58  ? 869  GLY A CA  1 
ATOM   5928 C C   . GLY A 1 910  ? 117.965 102.759 100.975 1.00 55.58  ? 869  GLY A C   1 
ATOM   5929 O O   . GLY A 1 910  ? 118.824 103.640 101.062 1.00 55.58  ? 869  GLY A O   1 
ATOM   5930 N N   . PHE A 1 911  ? 118.243 101.466 101.154 1.00 55.33  ? 870  PHE A N   1 
ATOM   5931 C CA  . PHE A 1 911  ? 119.576 101.004 101.526 1.00 55.33  ? 870  PHE A CA  1 
ATOM   5932 C C   . PHE A 1 911  ? 120.329 100.347 100.378 1.00 55.33  ? 870  PHE A C   1 
ATOM   5933 O O   . PHE A 1 911  ? 121.512 100.026 100.535 1.00 55.33  ? 870  PHE A O   1 
ATOM   5934 C CB  . PHE A 1 911  ? 119.505 100.031 102.703 1.00 55.33  ? 870  PHE A CB  1 
ATOM   5935 C CG  . PHE A 1 911  ? 118.988 100.646 103.965 1.00 55.33  ? 870  PHE A CG  1 
ATOM   5936 C CD1 . PHE A 1 911  ? 119.746 101.579 104.650 1.00 55.33  ? 870  PHE A CD1 1 
ATOM   5937 C CD2 . PHE A 1 911  ? 117.746 100.307 104.457 1.00 55.33  ? 870  PHE A CD2 1 
ATOM   5938 C CE1 . PHE A 1 911  ? 119.276 102.154 105.806 1.00 55.33  ? 870  PHE A CE1 1 
ATOM   5939 C CE2 . PHE A 1 911  ? 117.275 100.872 105.615 1.00 55.33  ? 870  PHE A CE2 1 
ATOM   5940 C CZ  . PHE A 1 911  ? 118.039 101.801 106.291 1.00 55.33  ? 870  PHE A CZ  1 
ATOM   5941 N N   . SER A 1 912  ? 119.687 100.131 99.237  1.00 66.10  ? 871  SER A N   1 
ATOM   5942 C CA  . SER A 1 912  ? 120.406 99.606  98.087  1.00 66.10  ? 871  SER A CA  1 
ATOM   5943 C C   . SER A 1 912  ? 121.284 100.695 97.490  1.00 66.10  ? 871  SER A C   1 
ATOM   5944 O O   . SER A 1 912  ? 120.810 101.788 97.165  1.00 66.10  ? 871  SER A O   1 
ATOM   5945 C CB  . SER A 1 912  ? 119.430 99.078  97.038  1.00 66.10  ? 871  SER A CB  1 
ATOM   5946 O OG  . SER A 1 912  ? 118.616 100.124 96.535  1.00 66.10  ? 871  SER A OG  1 
ATOM   5947 N N   . GLY A 1 913  ? 122.570 100.395 97.342  1.00 72.89  ? 872  GLY A N   1 
ATOM   5948 C CA  . GLY A 1 913  ? 123.522 101.358 96.837  1.00 72.89  ? 872  GLY A CA  1 
ATOM   5949 C C   . GLY A 1 913  ? 123.352 101.606 95.351  1.00 72.89  ? 872  GLY A C   1 
ATOM   5950 O O   . GLY A 1 913  ? 122.288 101.404 94.763  1.00 72.89  ? 872  GLY A O   1 
ATOM   5951 N N   . ASP A 1 914  ? 124.437 102.064 94.736  1.00 81.20  ? 873  ASP A N   1 
ATOM   5952 C CA  . ASP A 1 914  ? 124.457 102.282 93.292  1.00 81.20  ? 873  ASP A CA  1 
ATOM   5953 C C   . ASP A 1 914  ? 124.404 100.927 92.605  1.00 81.20  ? 873  ASP A C   1 
ATOM   5954 O O   . ASP A 1 914  ? 125.385 100.180 92.596  1.00 81.20  ? 873  ASP A O   1 
ATOM   5955 C CB  . ASP A 1 914  ? 125.699 103.063 92.883  1.00 81.20  ? 873  ASP A CB  1 
ATOM   5956 C CG  . ASP A 1 914  ? 125.574 103.670 91.501  1.00 81.20  ? 873  ASP A CG  1 
ATOM   5957 O OD1 . ASP A 1 914  ? 124.687 104.527 91.307  1.00 81.20  ? 873  ASP A OD1 1 
ATOM   5958 O OD2 . ASP A 1 914  ? 126.361 103.291 90.610  1.00 81.20  ? 873  ASP A OD2 1 
ATOM   5959 N N   . LEU A 1 915  ? 123.245 100.598 92.033  1.00 78.03  ? 874  LEU A N   1 
ATOM   5960 C CA  . LEU A 1 915  ? 123.092 99.314  91.355  1.00 78.03  ? 874  LEU A CA  1 
ATOM   5961 C C   . LEU A 1 915  ? 123.991 99.229  90.129  1.00 78.03  ? 874  LEU A C   1 
ATOM   5962 O O   . LEU A 1 915  ? 124.518 98.156  89.810  1.00 78.03  ? 874  LEU A O   1 
ATOM   5963 C CB  . LEU A 1 915  ? 121.630 99.100  90.970  1.00 78.03  ? 874  LEU A CB  1 
ATOM   5964 C CG  . LEU A 1 915  ? 120.632 99.139  92.129  1.00 78.03  ? 874  LEU A CG  1 
ATOM   5965 C CD1 . LEU A 1 915  ? 119.218 98.919  91.628  1.00 78.03  ? 874  LEU A CD1 1 
ATOM   5966 C CD2 . LEU A 1 915  ? 120.997 98.099  93.172  1.00 78.03  ? 874  LEU A CD2 1 
ATOM   5967 N N   . GLU A 1 916  ? 124.176 100.349 89.428  1.00 80.71  ? 875  GLU A N   1 
ATOM   5968 C CA  . GLU A 1 916  ? 125.032 100.356 88.247  1.00 80.71  ? 875  GLU A CA  1 
ATOM   5969 C C   . GLU A 1 916  ? 126.472 100.010 88.605  1.00 80.71  ? 875  GLU A C   1 
ATOM   5970 O O   . GLU A 1 916  ? 127.131 99.239  87.901  1.00 80.71  ? 875  GLU A O   1 
ATOM   5971 C CB  . GLU A 1 916  ? 124.964 101.719 87.563  1.00 80.71  ? 875  GLU A CB  1 
ATOM   5972 C CG  . GLU A 1 916  ? 123.641 102.011 86.891  1.00 80.71  ? 875  GLU A CG  1 
ATOM   5973 C CD  . GLU A 1 916  ? 123.810 102.823 85.626  1.00 80.71  ? 875  GLU A CD  1 
ATOM   5974 O OE1 . GLU A 1 916  ? 123.572 104.047 85.666  1.00 80.71  ? 875  GLU A OE1 1 
ATOM   5975 O OE2 . GLU A 1 916  ? 124.197 102.237 84.593  1.00 80.71  ? 875  GLU A OE2 1 
ATOM   5976 N N   . ALA A 1 917  ? 126.979 100.576 89.703  1.00 81.24  ? 876  ALA A N   1 
ATOM   5977 C CA  . ALA A 1 917  ? 128.363 100.326 90.089  1.00 81.24  ? 876  ALA A CA  1 
ATOM   5978 C C   . ALA A 1 917  ? 128.581 98.867  90.467  1.00 81.24  ? 876  ALA A C   1 
ATOM   5979 O O   . ALA A 1 917  ? 129.677 98.328  90.274  1.00 81.24  ? 876  ALA A O   1 
ATOM   5980 C CB  . ALA A 1 917  ? 128.759 101.242 91.245  1.00 81.24  ? 876  ALA A CB  1 
ATOM   5981 N N   . ALA A 1 918  ? 127.554 98.215  91.014  1.00 77.55  ? 877  ALA A N   1 
ATOM   5982 C CA  . ALA A 1 918  ? 127.688 96.812  91.393  1.00 77.55  ? 877  ALA A CA  1 
ATOM   5983 C C   . ALA A 1 918  ? 127.904 95.928  90.173  1.00 77.55  ? 877  ALA A C   1 
ATOM   5984 O O   . ALA A 1 918  ? 128.721 94.999  90.207  1.00 77.55  ? 877  ALA A O   1 
ATOM   5985 C CB  . ALA A 1 918  ? 126.456 96.360  92.174  1.00 77.55  ? 877  ALA A CB  1 
ATOM   5986 N N   . HIS A 1 919  ? 127.186 96.200  89.083  1.00 74.89  ? 878  HIS A N   1 
ATOM   5987 C CA  . HIS A 1 919  ? 127.251 95.385  87.877  1.00 74.89  ? 878  HIS A CA  1 
ATOM   5988 C C   . HIS A 1 919  ? 128.067 96.042  86.770  1.00 74.89  ? 878  HIS A C   1 
ATOM   5989 O O   . HIS A 1 919  ? 127.779 95.827  85.590  1.00 74.89  ? 878  HIS A O   1 
ATOM   5990 C CB  . HIS A 1 919  ? 125.843 95.076  87.370  1.00 74.89  ? 878  HIS A CB  1 
ATOM   5991 C CG  . HIS A 1 919  ? 124.865 94.754  88.454  1.00 74.89  ? 878  HIS A CG  1 
ATOM   5992 N ND1 . HIS A 1 919  ? 123.732 95.505  88.679  1.00 74.89  ? 878  HIS A ND1 1 
ATOM   5993 C CD2 . HIS A 1 919  ? 124.843 93.756  89.367  1.00 74.89  ? 878  HIS A CD2 1 
ATOM   5994 C CE1 . HIS A 1 919  ? 123.058 94.987  89.690  1.00 74.89  ? 878  HIS A CE1 1 
ATOM   5995 N NE2 . HIS A 1 919  ? 123.709 93.925  90.125  1.00 74.89  ? 878  HIS A NE2 1 
ATOM   5996 N N   . ALA A 1 920  ? 129.078 96.838  87.121  1.00 77.41  ? 879  ALA A N   1 
ATOM   5997 C CA  . ALA A 1 920  ? 129.854 97.540  86.104  1.00 77.41  ? 879  ALA A CA  1 
ATOM   5998 C C   . ALA A 1 920  ? 130.615 96.563  85.216  1.00 77.41  ? 879  ALA A C   1 
ATOM   5999 O O   . ALA A 1 920  ? 130.625 96.701  83.986  1.00 77.41  ? 879  ALA A O   1 
ATOM   6000 C CB  . ALA A 1 920  ? 130.813 98.527  86.767  1.00 77.41  ? 879  ALA A CB  1 
ATOM   6001 N N   . LYS A 1 921  ? 131.254 95.561  85.822  1.00 79.73  ? 880  LYS A N   1 
ATOM   6002 C CA  . LYS A 1 921  ? 132.040 94.599  85.055  1.00 79.73  ? 880  LYS A CA  1 
ATOM   6003 C C   . LYS A 1 921  ? 131.157 93.797  84.108  1.00 79.73  ? 880  LYS A C   1 
ATOM   6004 O O   . LYS A 1 921  ? 131.453 93.669  82.912  1.00 79.73  ? 880  LYS A O   1 
ATOM   6005 C CB  . LYS A 1 921  ? 132.790 93.670  86.009  1.00 79.73  ? 880  LYS A CB  1 
ATOM   6006 C CG  . LYS A 1 921  ? 133.775 92.738  85.333  1.00 79.73  ? 880  LYS A CG  1 
ATOM   6007 C CD  . LYS A 1 921  ? 134.471 91.847  86.348  1.00 79.73  ? 880  LYS A CD  1 
ATOM   6008 C CE  . LYS A 1 921  ? 135.430 92.641  87.217  1.00 79.73  ? 880  LYS A CE  1 
ATOM   6009 N NZ  . LYS A 1 921  ? 136.592 93.155  86.441  1.00 79.73  ? 880  LYS A NZ  1 
ATOM   6010 N N   . GLY A 1 922  ? 130.061 93.246  84.628  1.00 75.21  ? 881  GLY A N   1 
ATOM   6011 C CA  . GLY A 1 922  ? 129.144 92.512  83.777  1.00 75.21  ? 881  GLY A CA  1 
ATOM   6012 C C   . GLY A 1 922  ? 128.541 93.379  82.692  1.00 75.21  ? 881  GLY A C   1 
ATOM   6013 O O   . GLY A 1 922  ? 128.405 92.948  81.547  1.00 75.21  ? 881  GLY A O   1 
ATOM   6014 N N   . THR A 1 923  ? 128.176 94.616  83.034  1.00 78.79  ? 882  THR A N   1 
ATOM   6015 C CA  . THR A 1 923  ? 127.566 95.500  82.048  1.00 78.79  ? 882  THR A CA  1 
ATOM   6016 C C   . THR A 1 923  ? 128.538 95.820  80.921  1.00 78.79  ? 882  THR A C   1 
ATOM   6017 O O   . THR A 1 923  ? 128.156 95.835  79.746  1.00 78.79  ? 882  THR A O   1 
ATOM   6018 C CB  . THR A 1 923  ? 127.074 96.783  82.714  1.00 78.79  ? 882  THR A CB  1 
ATOM   6019 O OG1 . THR A 1 923  ? 126.105 96.458  83.717  1.00 78.79  ? 882  THR A OG1 1 
ATOM   6020 C CG2 . THR A 1 923  ? 126.435 97.705  81.686  1.00 78.79  ? 882  THR A CG2 1 
ATOM   6021 N N   . GLN A 1 924  ? 129.804 96.076  81.254  1.00 83.96  ? 883  GLN A N   1 
ATOM   6022 C CA  . GLN A 1 924  ? 130.766 96.392  80.202  1.00 83.96  ? 883  GLN A CA  1 
ATOM   6023 C C   . GLN A 1 924  ? 131.087 95.162  79.360  1.00 83.96  ? 883  GLN A C   1 
ATOM   6024 O O   . GLN A 1 924  ? 131.263 95.270  78.140  1.00 83.96  ? 883  GLN A O   1 
ATOM   6025 C CB  . GLN A 1 924  ? 132.022 97.031  80.805  1.00 83.96  ? 883  GLN A CB  1 
ATOM   6026 C CG  . GLN A 1 924  ? 132.840 96.182  81.767  1.00 83.96  ? 883  GLN A CG  1 
ATOM   6027 C CD  . GLN A 1 924  ? 133.829 95.258  81.087  1.00 83.96  ? 883  GLN A CD  1 
ATOM   6028 O OE1 . GLN A 1 924  ? 133.932 95.221  79.863  1.00 83.96  ? 883  GLN A OE1 1 
ATOM   6029 N NE2 . GLN A 1 924  ? 134.577 94.512  81.890  1.00 83.96  ? 883  GLN A NE2 1 
ATOM   6030 N N   . LEU A 1 925  ? 131.131 93.978  79.978  1.00 77.50  ? 884  LEU A N   1 
ATOM   6031 C CA  . LEU A 1 925  ? 131.300 92.760  79.188  1.00 77.50  ? 884  LEU A CA  1 
ATOM   6032 C C   . LEU A 1 925  ? 130.129 92.558  78.232  1.00 77.50  ? 884  LEU A C   1 
ATOM   6033 O O   . LEU A 1 925  ? 130.318 92.207  77.062  1.00 77.50  ? 884  LEU A O   1 
ATOM   6034 C CB  . LEU A 1 925  ? 131.453 91.546  80.099  1.00 77.50  ? 884  LEU A CB  1 
ATOM   6035 C CG  . LEU A 1 925  ? 131.523 90.221  79.338  1.00 77.50  ? 884  LEU A CG  1 
ATOM   6036 C CD1 . LEU A 1 925  ? 132.712 90.205  78.400  1.00 77.50  ? 884  LEU A CD1 1 
ATOM   6037 C CD2 . LEU A 1 925  ? 131.576 89.041  80.292  1.00 77.50  ? 884  LEU A CD2 1 
ATOM   6038 N N   . ALA A 1 926  ? 128.906 92.778  78.717  1.00 75.48  ? 885  ALA A N   1 
ATOM   6039 C CA  . ALA A 1 926  ? 127.732 92.613  77.869  1.00 75.48  ? 885  ALA A CA  1 
ATOM   6040 C C   . ALA A 1 926  ? 127.716 93.635  76.745  1.00 75.48  ? 885  ALA A C   1 
ATOM   6041 O O   . ALA A 1 926  ? 127.328 93.319  75.616  1.00 75.48  ? 885  ALA A O   1 
ATOM   6042 C CB  . ALA A 1 926  ? 126.460 92.720  78.707  1.00 75.48  ? 885  ALA A CB  1 
ATOM   6043 N N   . GLY A 1 927  ? 128.119 94.871  77.035  1.00 79.00  ? 886  GLY A N   1 
ATOM   6044 C CA  . GLY A 1 927  ? 128.205 95.872  75.986  1.00 79.00  ? 886  GLY A CA  1 
ATOM   6045 C C   . GLY A 1 927  ? 129.226 95.510  74.927  1.00 79.00  ? 886  GLY A C   1 
ATOM   6046 O O   . GLY A 1 927  ? 128.979 95.680  73.730  1.00 79.00  ? 886  GLY A O   1 
ATOM   6047 N N   . GLU A 1 928  ? 130.382 94.996  75.351  1.00 86.84  ? 887  GLU A N   1 
ATOM   6048 C CA  . GLU A 1 928  ? 131.386 94.549  74.392  1.00 86.84  ? 887  GLU A CA  1 
ATOM   6049 C C   . GLU A 1 928  ? 130.855 93.402  73.543  1.00 86.84  ? 887  GLU A C   1 
ATOM   6050 O O   . GLU A 1 928  ? 131.100 93.344  72.334  1.00 86.84  ? 887  GLU A O   1 
ATOM   6051 C CB  . GLU A 1 928  ? 132.660 94.133  75.123  1.00 86.84  ? 887  GLU A CB  1 
ATOM   6052 C CG  . GLU A 1 928  ? 133.497 95.297  75.614  1.00 86.84  ? 887  GLU A CG  1 
ATOM   6053 C CD  . GLU A 1 928  ? 134.668 94.853  76.465  1.00 86.84  ? 887  GLU A CD  1 
ATOM   6054 O OE1 . GLU A 1 928  ? 135.137 93.709  76.283  1.00 86.84  ? 887  GLU A OE1 1 
ATOM   6055 O OE2 . GLU A 1 928  ? 135.123 95.648  77.314  1.00 86.84  ? 887  GLU A OE2 1 
ATOM   6056 N N   . ALA A 1 929  ? 130.127 92.474  74.164  1.00 79.34  ? 888  ALA A N   1 
ATOM   6057 C CA  . ALA A 1 929  ? 129.590 91.338  73.421  1.00 79.34  ? 888  ALA A CA  1 
ATOM   6058 C C   . ALA A 1 929  ? 128.541 91.782  72.408  1.00 79.34  ? 888  ALA A C   1 
ATOM   6059 O O   . ALA A 1 929  ? 128.539 91.325  71.260  1.00 79.34  ? 888  ALA A O   1 
ATOM   6060 C CB  . ALA A 1 929  ? 129.008 90.308  74.385  1.00 79.34  ? 888  ALA A CB  1 
ATOM   6061 N N   . ILE A 1 930  ? 127.633 92.671  72.817  1.00 80.37  ? 889  ILE A N   1 
ATOM   6062 C CA  . ILE A 1 930  ? 126.566 93.104  71.918  1.00 80.37  ? 889  ILE A CA  1 
ATOM   6063 C C   . ILE A 1 930  ? 127.129 93.942  70.779  1.00 80.37  ? 889  ILE A C   1 
ATOM   6064 O O   . ILE A 1 930  ? 126.730 93.788  69.619  1.00 80.37  ? 889  ILE A O   1 
ATOM   6065 C CB  . ILE A 1 930  ? 125.478 93.867  72.694  1.00 80.37  ? 889  ILE A CB  1 
ATOM   6066 C CG1 . ILE A 1 930  ? 124.829 92.962  73.740  1.00 80.37  ? 889  ILE A CG1 1 
ATOM   6067 C CG2 . ILE A 1 930  ? 124.425 94.397  71.744  1.00 80.37  ? 889  ILE A CG2 1 
ATOM   6068 C CD1 . ILE A 1 930  ? 124.270 91.689  73.170  1.00 80.37  ? 889  ILE A CD1 1 
ATOM   6069 N N   . ALA A 1 931  ? 128.063 94.844  71.088  1.00 82.42  ? 890  ALA A N   1 
ATOM   6070 C CA  . ALA A 1 931  ? 128.673 95.655  70.039  1.00 82.42  ? 890  ALA A CA  1 
ATOM   6071 C C   . ALA A 1 931  ? 129.442 94.790  69.049  1.00 82.42  ? 890  ALA A C   1 
ATOM   6072 O O   . ALA A 1 931  ? 129.529 95.121  67.861  1.00 82.42  ? 890  ALA A O   1 
ATOM   6073 C CB  . ALA A 1 931  ? 129.588 96.710  70.658  1.00 82.42  ? 890  ALA A CB  1 
ATOM   6074 N N   . ASN A 1 932  ? 130.003 93.677  69.519  1.00 87.01  ? 891  ASN A N   1 
ATOM   6075 C CA  . ASN A 1 932  ? 130.798 92.778  68.695  1.00 87.01  ? 891  ASN A CA  1 
ATOM   6076 C C   . ASN A 1 932  ? 130.033 91.507  68.344  1.00 87.01  ? 891  ASN A C   1 
ATOM   6077 O O   . ASN A 1 932  ? 130.609 90.418  68.319  1.00 87.01  ? 891  ASN A O   1 
ATOM   6078 C CB  . ASN A 1 932  ? 132.102 92.430  69.408  1.00 87.01  ? 891  ASN A CB  1 
ATOM   6079 C CG  . ASN A 1 932  ? 133.046 93.605  69.491  1.00 87.01  ? 891  ASN A CG  1 
ATOM   6080 O OD1 . ASN A 1 932  ? 133.202 94.358  68.532  1.00 87.01  ? 891  ASN A OD1 1 
ATOM   6081 N ND2 . ASN A 1 932  ? 133.680 93.775  70.645  1.00 87.01  ? 891  ASN A ND2 1 
ATOM   6082 N N   . VAL A 1 933  ? 128.732 91.634  68.071  1.00 85.52  ? 892  VAL A N   1 
ATOM   6083 C CA  . VAL A 1 933  ? 127.890 90.457  67.872  1.00 85.52  ? 892  VAL A CA  1 
ATOM   6084 C C   . VAL A 1 933  ? 128.340 89.669  66.648  1.00 85.52  ? 892  VAL A C   1 
ATOM   6085 O O   . VAL A 1 933  ? 128.240 88.438  66.617  1.00 85.52  ? 892  VAL A O   1 
ATOM   6086 C CB  . VAL A 1 933  ? 126.409 90.868  67.779  1.00 85.52  ? 892  VAL A CB  1 
ATOM   6087 C CG1 . VAL A 1 933  ? 126.161 91.731  66.557  1.00 85.52  ? 892  VAL A CG1 1 
ATOM   6088 C CG2 . VAL A 1 933  ? 125.518 89.641  67.757  1.00 85.52  ? 892  VAL A CG2 1 
ATOM   6089 N N   . ARG A 1 934  ? 128.841 90.359  65.623  1.00 95.84  ? 893  ARG A N   1 
ATOM   6090 C CA  . ARG A 1 934  ? 129.301 89.666  64.425  1.00 95.84  ? 893  ARG A CA  1 
ATOM   6091 C C   . ARG A 1 934  ? 130.479 88.753  64.740  1.00 95.84  ? 893  ARG A C   1 
ATOM   6092 O O   . ARG A 1 934  ? 130.529 87.605  64.287  1.00 95.84  ? 893  ARG A O   1 
ATOM   6093 C CB  . ARG A 1 934  ? 129.675 90.677  63.343  1.00 95.84  ? 893  ARG A CB  1 
ATOM   6094 C CG  . ARG A 1 934  ? 128.498 91.476  62.813  1.00 95.84  ? 893  ARG A CG  1 
ATOM   6095 C CD  . ARG A 1 934  ? 128.936 92.429  61.719  1.00 95.84  ? 893  ARG A CD  1 
ATOM   6096 N NE  . ARG A 1 934  ? 130.071 91.901  60.973  1.00 95.84  ? 893  ARG A NE  1 
ATOM   6097 C CZ  . ARG A 1 934  ? 130.063 91.663  59.669  1.00 95.84  ? 893  ARG A CZ  1 
ATOM   6098 N NH1 . ARG A 1 934  ? 128.993 91.902  58.929  1.00 95.84  ? 893  ARG A NH1 1 
ATOM   6099 N NH2 . ARG A 1 934  ? 131.157 91.173  59.093  1.00 95.84  ? 893  ARG A NH2 1 
ATOM   6100 N N   . THR A 1 935  ? 131.437 89.248  65.525  1.00 91.62  ? 894  THR A N   1 
ATOM   6101 C CA  . THR A 1 935  ? 132.582 88.424  65.901  1.00 91.62  ? 894  THR A CA  1 
ATOM   6102 C C   . THR A 1 935  ? 132.155 87.253  66.775  1.00 91.62  ? 894  THR A C   1 
ATOM   6103 O O   . THR A 1 935  ? 132.670 86.139  66.628  1.00 91.62  ? 894  THR A O   1 
ATOM   6104 C CB  . THR A 1 935  ? 133.625 89.272  66.625  1.00 91.62  ? 894  THR A CB  1 
ATOM   6105 O OG1 . THR A 1 935  ? 133.052 89.805  67.823  1.00 91.62  ? 894  THR A OG1 1 
ATOM   6106 C CG2 . THR A 1 935  ? 134.075 90.420  65.742  1.00 91.62  ? 894  THR A CG2 1 
ATOM   6107 N N   . VAL A 1 936  ? 131.221 87.489  67.700  1.00 87.51  ? 895  VAL A N   1 
ATOM   6108 C CA  . VAL A 1 936  ? 130.745 86.419  68.573  1.00 87.51  ? 895  VAL A CA  1 
ATOM   6109 C C   . VAL A 1 936  ? 130.080 85.323  67.754  1.00 87.51  ? 895  VAL A C   1 
ATOM   6110 O O   . VAL A 1 936  ? 130.319 84.129  67.970  1.00 87.51  ? 895  VAL A O   1 
ATOM   6111 C CB  . VAL A 1 936  ? 129.788 86.981  69.639  1.00 87.51  ? 895  VAL A CB  1 
ATOM   6112 C CG1 . VAL A 1 936  ? 129.211 85.857  70.474  1.00 87.51  ? 895  VAL A CG1 1 
ATOM   6113 C CG2 . VAL A 1 936  ? 130.508 87.977  70.520  1.00 87.51  ? 895  VAL A CG2 1 
ATOM   6114 N N   . ALA A 1 937  ? 129.233 85.710  66.800  1.00 92.09  ? 896  ALA A N   1 
ATOM   6115 C CA  . ALA A 1 937  ? 128.558 84.719  65.972  1.00 92.09  ? 896  ALA A CA  1 
ATOM   6116 C C   . ALA A 1 937  ? 129.539 84.006  65.051  1.00 92.09  ? 896  ALA A C   1 
ATOM   6117 O O   . ALA A 1 937  ? 129.380 82.814  64.766  1.00 92.09  ? 896  ALA A O   1 
ATOM   6118 C CB  . ALA A 1 937  ? 127.445 85.381  65.162  1.00 92.09  ? 896  ALA A CB  1 
ATOM   6119 N N   . ALA A 1 938  ? 130.558 84.722  64.570  1.00 95.60  ? 897  ALA A N   1 
ATOM   6120 C CA  . ALA A 1 938  ? 131.534 84.111  63.675  1.00 95.60  ? 897  ALA A CA  1 
ATOM   6121 C C   . ALA A 1 938  ? 132.300 82.996  64.372  1.00 95.60  ? 897  ALA A C   1 
ATOM   6122 O O   . ALA A 1 938  ? 132.595 81.960  63.766  1.00 95.60  ? 897  ALA A O   1 
ATOM   6123 C CB  . ALA A 1 938  ? 132.496 85.174  63.147  1.00 95.60  ? 897  ALA A CB  1 
ATOM   6124 N N   . PHE A 1 939  ? 132.637 83.192  65.642  1.00 94.89  ? 898  PHE A N   1 
ATOM   6125 C CA  . PHE A 1 939  ? 133.332 82.190  66.434  1.00 94.89  ? 898  PHE A CA  1 
ATOM   6126 C C   . PHE A 1 939  ? 132.377 81.314  67.231  1.00 94.89  ? 898  PHE A C   1 
ATOM   6127 O O   . PHE A 1 939  ? 132.830 80.602  68.130  1.00 94.89  ? 898  PHE A O   1 
ATOM   6128 C CB  . PHE A 1 939  ? 134.325 82.867  67.378  1.00 94.89  ? 898  PHE A CB  1 
ATOM   6129 C CG  . PHE A 1 939  ? 135.484 83.504  66.674  1.00 94.89  ? 898  PHE A CG  1 
ATOM   6130 C CD1 . PHE A 1 939  ? 136.398 82.733  65.982  1.00 94.89  ? 898  PHE A CD1 1 
ATOM   6131 C CD2 . PHE A 1 939  ? 135.650 84.877  66.690  1.00 94.89  ? 898  PHE A CD2 1 
ATOM   6132 C CE1 . PHE A 1 939  ? 137.461 83.317  65.329  1.00 94.89  ? 898  PHE A CE1 1 
ATOM   6133 C CE2 . PHE A 1 939  ? 136.711 85.465  66.037  1.00 94.89  ? 898  PHE A CE2 1 
ATOM   6134 C CZ  . PHE A 1 939  ? 137.618 84.685  65.356  1.00 94.89  ? 898  PHE A CZ  1 
ATOM   6135 N N   . ASN A 1 940  ? 131.077 81.407  66.949  1.00 93.46  ? 899  ASN A N   1 
ATOM   6136 C CA  . ASN A 1 940  ? 129.996 80.624  67.563  1.00 93.46  ? 899  ASN A CA  1 
ATOM   6137 C C   . ASN A 1 940  ? 130.273 80.328  69.038  1.00 93.46  ? 899  ASN A C   1 
ATOM   6138 O O   . ASN A 1 940  ? 130.237 79.189  69.502  1.00 93.46  ? 899  ASN A O   1 
ATOM   6139 C CB  . ASN A 1 940  ? 129.684 79.355  66.754  1.00 93.46  ? 899  ASN A CB  1 
ATOM   6140 C CG  . ASN A 1 940  ? 130.847 78.373  66.656  1.00 93.46  ? 899  ASN A CG  1 
ATOM   6141 O OD1 . ASN A 1 940  ? 131.800 78.414  67.425  1.00 93.46  ? 899  ASN A OD1 1 
ATOM   6142 N ND2 . ASN A 1 940  ? 130.761 77.477  65.681  1.00 93.46  ? 899  ASN A ND2 1 
ATOM   6143 N N   . SER A 1 941  ? 130.532 81.404  69.779  1.00 83.82  ? 900  SER A N   1 
ATOM   6144 C CA  . SER A 1 941  ? 130.878 81.329  71.192  1.00 83.82  ? 900  SER A CA  1 
ATOM   6145 C C   . SER A 1 941  ? 129.879 82.085  72.059  1.00 83.82  ? 900  SER A C   1 
ATOM   6146 O O   . SER A 1 941  ? 130.268 82.788  72.992  1.00 83.82  ? 900  SER A O   1 
ATOM   6147 C CB  . SER A 1 941  ? 132.289 81.865  71.422  1.00 83.82  ? 900  SER A CB  1 
ATOM   6148 O OG  . SER A 1 941  ? 132.390 83.210  70.991  1.00 83.82  ? 900  SER A OG  1 
ATOM   6149 N N   . GLU A 1 942  ? 128.586 81.964  71.755  1.00 80.79  ? 901  GLU A N   1 
ATOM   6150 C CA  . GLU A 1 942  ? 127.573 82.639  72.560  1.00 80.79  ? 901  GLU A CA  1 
ATOM   6151 C C   . GLU A 1 942  ? 127.525 82.070  73.973  1.00 80.79  ? 901  GLU A C   1 
ATOM   6152 O O   . GLU A 1 942  ? 127.418 82.816  74.954  1.00 80.79  ? 901  GLU A O   1 
ATOM   6153 C CB  . GLU A 1 942  ? 126.209 82.523  71.885  1.00 80.79  ? 901  GLU A CB  1 
ATOM   6154 C CG  . GLU A 1 942  ? 126.156 83.130  70.498  1.00 80.79  ? 901  GLU A CG  1 
ATOM   6155 C CD  . GLU A 1 942  ? 126.177 82.082  69.406  1.00 80.79  ? 901  GLU A CD  1 
ATOM   6156 O OE1 . GLU A 1 942  ? 125.318 82.144  68.502  1.00 80.79  ? 901  GLU A OE1 1 
ATOM   6157 O OE2 . GLU A 1 942  ? 127.055 81.196  69.451  1.00 80.79  ? 901  GLU A OE2 1 
ATOM   6158 N N   . ALA A 1 943  ? 127.605 80.744  74.095  1.00 75.02  ? 902  ALA A N   1 
ATOM   6159 C CA  . ALA A 1 943  ? 127.524 80.113  75.408  1.00 75.02  ? 902  ALA A CA  1 
ATOM   6160 C C   . ALA A 1 943  ? 128.695 80.520  76.293  1.00 75.02  ? 902  ALA A C   1 
ATOM   6161 O O   . ALA A 1 943  ? 128.528 80.726  77.501  1.00 75.02  ? 902  ALA A O   1 
ATOM   6162 C CB  . ALA A 1 943  ? 127.465 78.595  75.258  1.00 75.02  ? 902  ALA A CB  1 
ATOM   6163 N N   . LYS A 1 944  ? 129.893 80.621  75.715  1.00 76.12  ? 903  LYS A N   1 
ATOM   6164 C CA  . LYS A 1 944  ? 131.055 81.037  76.492  1.00 76.12  ? 903  LYS A CA  1 
ATOM   6165 C C   . LYS A 1 944  ? 130.870 82.447  77.034  1.00 76.12  ? 903  LYS A C   1 
ATOM   6166 O O   . LYS A 1 944  ? 131.178 82.724  78.198  1.00 76.12  ? 903  LYS A O   1 
ATOM   6167 C CB  . LYS A 1 944  ? 132.315 80.949  75.635  1.00 76.12  ? 903  LYS A CB  1 
ATOM   6168 C CG  . LYS A 1 944  ? 133.586 81.319  76.369  1.00 76.12  ? 903  LYS A CG  1 
ATOM   6169 C CD  . LYS A 1 944  ? 133.853 80.347  77.501  1.00 76.12  ? 903  LYS A CD  1 
ATOM   6170 C CE  . LYS A 1 944  ? 134.237 78.978  76.966  1.00 76.12  ? 903  LYS A CE  1 
ATOM   6171 N NZ  . LYS A 1 944  ? 134.564 78.020  78.057  1.00 76.12  ? 903  LYS A NZ  1 
ATOM   6172 N N   . ILE A 1 945  ? 130.362 83.354  76.199  1.00 72.69  ? 904  ILE A N   1 
ATOM   6173 C CA  . ILE A 1 945  ? 130.116 84.719  76.655  1.00 72.69  ? 904  ILE A CA  1 
ATOM   6174 C C   . ILE A 1 945  ? 129.060 84.732  77.749  1.00 72.69  ? 904  ILE A C   1 
ATOM   6175 O O   . ILE A 1 945  ? 129.174 85.472  78.732  1.00 72.69  ? 904  ILE A O   1 
ATOM   6176 C CB  . ILE A 1 945  ? 129.718 85.620  75.473  1.00 72.69  ? 904  ILE A CB  1 
ATOM   6177 C CG1 . ILE A 1 945  ? 130.802 85.597  74.398  1.00 72.69  ? 904  ILE A CG1 1 
ATOM   6178 C CG2 . ILE A 1 945  ? 129.484 87.037  75.946  1.00 72.69  ? 904  ILE A CG2 1 
ATOM   6179 C CD1 . ILE A 1 945  ? 132.193 85.820  74.936  1.00 72.69  ? 904  ILE A CD1 1 
ATOM   6180 N N   . VAL A 1 946  ? 128.019 83.912  77.601  1.00 71.02  ? 905  VAL A N   1 
ATOM   6181 C CA  . VAL A 1 946  ? 126.969 83.863  78.616  1.00 71.02  ? 905  VAL A CA  1 
ATOM   6182 C C   . VAL A 1 946  ? 127.528 83.373  79.946  1.00 71.02  ? 905  VAL A C   1 
ATOM   6183 O O   . VAL A 1 946  ? 127.205 83.917  81.011  1.00 71.02  ? 905  VAL A O   1 
ATOM   6184 C CB  . VAL A 1 946  ? 125.799 82.990  78.132  1.00 71.02  ? 905  VAL A CB  1 
ATOM   6185 C CG1 . VAL A 1 946  ? 124.843 82.705  79.273  1.00 71.02  ? 905  VAL A CG1 1 
ATOM   6186 C CG2 . VAL A 1 946  ? 125.069 83.681  76.997  1.00 71.02  ? 905  VAL A CG2 1 
ATOM   6187 N N   . ARG A 1 947  ? 128.374 82.342  79.916  1.00 73.41  ? 906  ARG A N   1 
ATOM   6188 C CA  . ARG A 1 947  ? 128.896 81.804  81.168  1.00 73.41  ? 906  ARG A CA  1 
ATOM   6189 C C   . ARG A 1 947  ? 129.902 82.762  81.800  1.00 73.41  ? 906  ARG A C   1 
ATOM   6190 O O   . ARG A 1 947  ? 129.984 82.867  83.030  1.00 73.41  ? 906  ARG A O   1 
ATOM   6191 C CB  . ARG A 1 947  ? 129.507 80.419  80.947  1.00 73.41  ? 906  ARG A CB  1 
ATOM   6192 C CG  . ARG A 1 947  ? 130.850 80.400  80.253  1.00 73.41  ? 906  ARG A CG  1 
ATOM   6193 C CD  . ARG A 1 947  ? 131.356 78.977  80.086  1.00 73.41  ? 906  ARG A CD  1 
ATOM   6194 N NE  . ARG A 1 947  ? 130.547 78.221  79.138  1.00 73.41  ? 906  ARG A NE  1 
ATOM   6195 C CZ  . ARG A 1 947  ? 129.667 77.292  79.480  1.00 73.41  ? 906  ARG A CZ  1 
ATOM   6196 N NH1 . ARG A 1 947  ? 129.435 76.991  80.746  1.00 73.41  ? 906  ARG A NH1 1 
ATOM   6197 N NH2 . ARG A 1 947  ? 128.997 76.651  78.526  1.00 73.41  ? 906  ARG A NH2 1 
ATOM   6198 N N   . LEU A 1 948  ? 130.658 83.495  80.979  1.00 73.51  ? 907  LEU A N   1 
ATOM   6199 C CA  . LEU A 1 948  ? 131.517 84.542  81.527  1.00 73.51  ? 907  LEU A CA  1 
ATOM   6200 C C   . LEU A 1 948  ? 130.688 85.646  82.168  1.00 73.51  ? 907  LEU A C   1 
ATOM   6201 O O   . LEU A 1 948  ? 131.058 86.181  83.220  1.00 73.51  ? 907  LEU A O   1 
ATOM   6202 C CB  . LEU A 1 948  ? 132.420 85.117  80.440  1.00 73.51  ? 907  LEU A CB  1 
ATOM   6203 C CG  . LEU A 1 948  ? 133.505 84.190  79.895  1.00 73.51  ? 907  LEU A CG  1 
ATOM   6204 C CD1 . LEU A 1 948  ? 134.413 84.946  78.941  1.00 73.51  ? 907  LEU A CD1 1 
ATOM   6205 C CD2 . LEU A 1 948  ? 134.303 83.584  81.036  1.00 73.51  ? 907  LEU A CD2 1 
ATOM   6206 N N   . TYR A 1 949  ? 129.565 86.001  81.545  1.00 67.31  ? 908  TYR A N   1 
ATOM   6207 C CA  . TYR A 1 949  ? 128.668 86.991  82.126  1.00 67.31  ? 908  TYR A CA  1 
ATOM   6208 C C   . TYR A 1 949  ? 128.130 86.515  83.469  1.00 67.31  ? 908  TYR A C   1 
ATOM   6209 O O   . TYR A 1 949  ? 128.056 87.290  84.429  1.00 67.31  ? 908  TYR A O   1 
ATOM   6210 C CB  . TYR A 1 949  ? 127.528 87.270  81.149  1.00 67.31  ? 908  TYR A CB  1 
ATOM   6211 C CG  . TYR A 1 949  ? 126.669 88.459  81.487  1.00 67.31  ? 908  TYR A CG  1 
ATOM   6212 C CD1 . TYR A 1 949  ? 127.234 89.683  81.789  1.00 67.31  ? 908  TYR A CD1 1 
ATOM   6213 C CD2 . TYR A 1 949  ? 125.288 88.362  81.472  1.00 67.31  ? 908  TYR A CD2 1 
ATOM   6214 C CE1 . TYR A 1 949  ? 126.447 90.770  82.086  1.00 67.31  ? 908  TYR A CE1 1 
ATOM   6215 C CE2 . TYR A 1 949  ? 124.496 89.445  81.766  1.00 67.31  ? 908  TYR A CE2 1 
ATOM   6216 C CZ  . TYR A 1 949  ? 125.080 90.648  82.072  1.00 67.31  ? 908  TYR A CZ  1 
ATOM   6217 O OH  . TYR A 1 949  ? 124.295 91.735  82.368  1.00 67.31  ? 908  TYR A OH  1 
ATOM   6218 N N   . THR A 1 950  ? 127.762 85.238  83.555  1.00 67.05  ? 909  THR A N   1 
ATOM   6219 C CA  . THR A 1 950  ? 127.294 84.679  84.820  1.00 67.05  ? 909  THR A CA  1 
ATOM   6220 C C   . THR A 1 950  ? 128.386 84.733  85.885  1.00 67.05  ? 909  THR A C   1 
ATOM   6221 O O   . THR A 1 950  ? 128.130 85.091  87.044  1.00 67.05  ? 909  THR A O   1 
ATOM   6222 C CB  . THR A 1 950  ? 126.827 83.241  84.607  1.00 67.05  ? 909  THR A CB  1 
ATOM   6223 O OG1 . THR A 1 950  ? 125.945 83.188  83.480  1.00 67.05  ? 909  THR A OG1 1 
ATOM   6224 C CG2 . THR A 1 950  ? 126.101 82.730  85.833  1.00 67.05  ? 909  THR A CG2 1 
ATOM   6225 N N   . ALA A 1 951  ? 129.611 84.364  85.509  1.00 65.89  ? 910  ALA A N   1 
ATOM   6226 C CA  . ALA A 1 951  ? 130.712 84.374  86.466  1.00 65.89  ? 910  ALA A CA  1 
ATOM   6227 C C   . ALA A 1 951  ? 131.027 85.789  86.927  1.00 65.89  ? 910  ALA A C   1 
ATOM   6228 O O   . ALA A 1 951  ? 131.476 85.995  88.060  1.00 65.89  ? 910  ALA A O   1 
ATOM   6229 C CB  . ALA A 1 951  ? 131.948 83.720  85.852  1.00 65.89  ? 910  ALA A CB  1 
ATOM   6230 N N   . ASN A 1 952  ? 130.814 86.779  86.060  1.00 68.03  ? 911  ASN A N   1 
ATOM   6231 C CA  . ASN A 1 952  ? 131.016 88.161  86.474  1.00 68.03  ? 911  ASN A CA  1 
ATOM   6232 C C   . ASN A 1 952  ? 129.878 88.658  87.356  1.00 68.03  ? 911  ASN A C   1 
ATOM   6233 O O   . ASN A 1 952  ? 130.101 89.500  88.232  1.00 68.03  ? 911  ASN A O   1 
ATOM   6234 C CB  . ASN A 1 952  ? 131.168 89.066  85.253  1.00 68.03  ? 911  ASN A CB  1 
ATOM   6235 C CG  . ASN A 1 952  ? 132.460 88.823  84.508  1.00 68.03  ? 911  ASN A CG  1 
ATOM   6236 O OD1 . ASN A 1 952  ? 133.212 87.904  84.830  1.00 68.03  ? 911  ASN A OD1 1 
ATOM   6237 N ND2 . ASN A 1 952  ? 132.730 89.651  83.509  1.00 68.03  ? 911  ASN A ND2 1 
ATOM   6238 N N   . LEU A 1 953  ? 128.662 88.164  87.137  1.00 63.91  ? 912  LEU A N   1 
ATOM   6239 C CA  . LEU A 1 953  ? 127.504 88.606  87.903  1.00 63.91  ? 912  LEU A CA  1 
ATOM   6240 C C   . LEU A 1 953  ? 127.384 87.944  89.270  1.00 63.91  ? 912  LEU A C   1 
ATOM   6241 O O   . LEU A 1 953  ? 126.665 88.468  90.125  1.00 63.91  ? 912  LEU A O   1 
ATOM   6242 C CB  . LEU A 1 953  ? 126.219 88.352  87.110  1.00 63.91  ? 912  LEU A CB  1 
ATOM   6243 C CG  . LEU A 1 953  ? 125.900 89.340  85.989  1.00 63.91  ? 912  LEU A CG  1 
ATOM   6244 C CD1 . LEU A 1 953  ? 124.448 89.221  85.580  1.00 63.91  ? 912  LEU A CD1 1 
ATOM   6245 C CD2 . LEU A 1 953  ? 126.220 90.759  86.421  1.00 63.91  ? 912  LEU A CD2 1 
ATOM   6246 N N   . GLU A 1 954  ? 128.039 86.801  89.490  1.00 63.05  ? 913  GLU A N   1 
ATOM   6247 C CA  . GLU A 1 954  ? 127.927 86.146  90.796  1.00 63.05  ? 913  GLU A CA  1 
ATOM   6248 C C   . GLU A 1 954  ? 128.448 87.000  91.954  1.00 63.05  ? 913  GLU A C   1 
ATOM   6249 O O   . GLU A 1 954  ? 127.767 87.064  92.997  1.00 63.05  ? 913  GLU A O   1 
ATOM   6250 C CB  . GLU A 1 954  ? 128.614 84.778  90.756  1.00 63.05  ? 913  GLU A CB  1 
ATOM   6251 C CG  . GLU A 1 954  ? 127.907 83.766  89.885  1.00 63.05  ? 913  GLU A CG  1 
ATOM   6252 C CD  . GLU A 1 954  ? 126.415 83.740  90.132  1.00 63.05  ? 913  GLU A CD  1 
ATOM   6253 O OE1 . GLU A 1 954  ? 126.005 83.385  91.257  1.00 63.05  ? 913  GLU A OE1 1 
ATOM   6254 O OE2 . GLU A 1 954  ? 125.651 84.080  89.204  1.00 63.05  ? 913  GLU A OE2 1 
ATOM   6255 N N   . PRO A 1 955  ? 129.624 87.625  91.881  1.00 61.71  ? 914  PRO A N   1 
ATOM   6256 C CA  . PRO A 1 955  ? 130.113 88.413  93.024  1.00 61.71  ? 914  PRO A CA  1 
ATOM   6257 C C   . PRO A 1 955  ? 129.167 89.541  93.407  1.00 61.71  ? 914  PRO A C   1 
ATOM   6258 O O   . PRO A 1 955  ? 128.991 89.805  94.605  1.00 61.71  ? 914  PRO A O   1 
ATOM   6259 C CB  . PRO A 1 955  ? 131.468 88.947  92.536  1.00 61.71  ? 914  PRO A CB  1 
ATOM   6260 C CG  . PRO A 1 955  ? 131.916 87.944  91.561  1.00 61.71  ? 914  PRO A CG  1 
ATOM   6261 C CD  . PRO A 1 955  ? 130.678 87.469  90.860  1.00 61.71  ? 914  PRO A CD  1 
ATOM   6262 N N   . PRO A 1 956  ? 128.548 90.249  92.447  1.00 61.47  ? 915  PRO A N   1 
ATOM   6263 C CA  . PRO A 1 956  ? 127.496 91.194  92.854  1.00 61.47  ? 915  PRO A CA  1 
ATOM   6264 C C   . PRO A 1 956  ? 126.346 90.534  93.588  1.00 61.47  ? 915  PRO A C   1 
ATOM   6265 O O   . PRO A 1 956  ? 125.800 91.130  94.518  1.00 61.47  ? 915  PRO A O   1 
ATOM   6266 C CB  . PRO A 1 956  ? 127.046 91.812  91.527  1.00 61.47  ? 915  PRO A CB  1 
ATOM   6267 C CG  . PRO A 1 956  ? 128.233 91.752  90.682  1.00 61.47  ? 915  PRO A CG  1 
ATOM   6268 C CD  . PRO A 1 956  ? 128.938 90.479  91.042  1.00 61.47  ? 915  PRO A CD  1 
ATOM   6269 N N   . LEU A 1 957  ? 125.971 89.312  93.206  1.00 60.72  ? 916  LEU A N   1 
ATOM   6270 C CA  . LEU A 1 957  ? 124.908 88.604  93.913  1.00 60.72  ? 916  LEU A CA  1 
ATOM   6271 C C   . LEU A 1 957  ? 125.287 88.365  95.369  1.00 60.72  ? 916  LEU A C   1 
ATOM   6272 O O   . LEU A 1 957  ? 124.508 88.658  96.289  1.00 60.72  ? 916  LEU A O   1 
ATOM   6273 C CB  . LEU A 1 957  ? 124.616 87.277  93.212  1.00 60.72  ? 916  LEU A CB  1 
ATOM   6274 C CG  . LEU A 1 957  ? 123.265 86.600  93.437  1.00 60.72  ? 916  LEU A CG  1 
ATOM   6275 C CD1 . LEU A 1 957  ? 122.163 87.337  92.708  1.00 60.72  ? 916  LEU A CD1 1 
ATOM   6276 C CD2 . LEU A 1 957  ? 123.321 85.147  93.000  1.00 60.72  ? 916  LEU A CD2 1 
ATOM   6277 N N   . LYS A 1 958  ? 126.492 87.839  95.598  1.00 61.57  ? 917  LYS A N   1 
ATOM   6278 C CA  . LYS A 1 958  ? 126.926 87.559  96.964  1.00 61.57  ? 917  LYS A CA  1 
ATOM   6279 C C   . LYS A 1 958  ? 127.048 88.844  97.778  1.00 61.57  ? 917  LYS A C   1 
ATOM   6280 O O   . LYS A 1 958  ? 126.640 88.902  98.949  1.00 61.57  ? 917  LYS A O   1 
ATOM   6281 C CB  . LYS A 1 958  ? 128.253 86.805  96.940  1.00 61.57  ? 917  LYS A CB  1 
ATOM   6282 C CG  . LYS A 1 958  ? 128.726 86.327  98.297  1.00 61.57  ? 917  LYS A CG  1 
ATOM   6283 C CD  . LYS A 1 958  ? 130.040 85.576  98.178  1.00 61.57  ? 917  LYS A CD  1 
ATOM   6284 C CE  . LYS A 1 958  ? 129.958 84.473  97.132  1.00 61.57  ? 917  LYS A CE  1 
ATOM   6285 N NZ  . LYS A 1 958  ? 128.872 83.497  97.422  1.00 61.57  ? 917  LYS A NZ  1 
ATOM   6286 N N   . ARG A 1 959  ? 127.610 89.889  97.167  1.00 61.80  ? 918  ARG A N   1 
ATOM   6287 C CA  . ARG A 1 959  ? 127.760 91.162  97.859  1.00 61.80  ? 918  ARG A CA  1 
ATOM   6288 C C   . ARG A 1 959  ? 126.403 91.752  98.213  1.00 61.80  ? 918  ARG A C   1 
ATOM   6289 O O   . ARG A 1 959  ? 126.225 92.311  99.298  1.00 61.80  ? 918  ARG A O   1 
ATOM   6290 C CB  . ARG A 1 959  ? 128.568 92.133  97.000  1.00 61.80  ? 918  ARG A CB  1 
ATOM   6291 C CG  . ARG A 1 959  ? 128.615 93.552  97.541  1.00 61.80  ? 918  ARG A CG  1 
ATOM   6292 C CD  . ARG A 1 959  ? 129.275 93.601  98.911  1.00 61.80  ? 918  ARG A CD  1 
ATOM   6293 N NE  . ARG A 1 959  ? 128.940 94.811  99.653  1.00 61.80  ? 918  ARG A NE  1 
ATOM   6294 C CZ  . ARG A 1 959  ? 129.349 96.033  99.334  1.00 61.80  ? 918  ARG A CZ  1 
ATOM   6295 N NH1 . ARG A 1 959  ? 130.138 96.250  98.295  1.00 61.80  ? 918  ARG A NH1 1 
ATOM   6296 N NH2 . ARG A 1 959  ? 128.960 97.062  100.081 1.00 61.80  ? 918  ARG A NH2 1 
ATOM   6297 N N   . CYS A 1 960  ? 125.428 91.636  97.309  1.00 61.04  ? 919  CYS A N   1 
ATOM   6298 C CA  . CYS A 1 960  ? 124.092 92.142  97.596  1.00 61.04  ? 919  CYS A CA  1 
ATOM   6299 C C   . CYS A 1 960  ? 123.446 91.375  98.740  1.00 61.04  ? 919  CYS A C   1 
ATOM   6300 O O   . CYS A 1 960  ? 122.791 91.972  99.601  1.00 61.04  ? 919  CYS A O   1 
ATOM   6301 C CB  . CYS A 1 960  ? 123.219 92.068  96.345  1.00 61.04  ? 919  CYS A CB  1 
ATOM   6302 S SG  . CYS A 1 960  ? 121.583 92.797  96.546  1.00 61.04  ? 919  CYS A SG  1 
ATOM   6303 N N   . PHE A 1 961  ? 123.618 90.052  98.768  1.00 56.00  ? 920  PHE A N   1 
ATOM   6304 C CA  . PHE A 1 961  ? 123.070 89.272  99.875  1.00 56.00  ? 920  PHE A CA  1 
ATOM   6305 C C   . PHE A 1 961  ? 123.648 89.731  101.209 1.00 56.00  ? 920  PHE A C   1 
ATOM   6306 O O   . PHE A 1 961  ? 122.905 90.007  102.165 1.00 56.00  ? 920  PHE A O   1 
ATOM   6307 C CB  . PHE A 1 961  ? 123.350 87.787  99.661  1.00 56.00  ? 920  PHE A CB  1 
ATOM   6308 C CG  . PHE A 1 961  ? 123.019 86.934  100.850 1.00 56.00  ? 920  PHE A CG  1 
ATOM   6309 C CD1 . PHE A 1 961  ? 121.704 86.723  101.220 1.00 56.00  ? 920  PHE A CD1 1 
ATOM   6310 C CD2 . PHE A 1 961  ? 124.021 86.357  101.606 1.00 56.00  ? 920  PHE A CD2 1 
ATOM   6311 C CE1 . PHE A 1 961  ? 121.395 85.940  102.312 1.00 56.00  ? 920  PHE A CE1 1 
ATOM   6312 C CE2 . PHE A 1 961  ? 123.716 85.576  102.702 1.00 56.00  ? 920  PHE A CE2 1 
ATOM   6313 C CZ  . PHE A 1 961  ? 122.402 85.368  103.055 1.00 56.00  ? 920  PHE A CZ  1 
ATOM   6314 N N   . TRP A 1 962  ? 124.976 89.826  101.292 1.00 56.06  ? 921  TRP A N   1 
ATOM   6315 C CA  . TRP A 1 962  ? 125.592 90.208  102.561 1.00 56.06  ? 921  TRP A CA  1 
ATOM   6316 C C   . TRP A 1 962  ? 125.257 91.648  102.934 1.00 56.06  ? 921  TRP A C   1 
ATOM   6317 O O   . TRP A 1 962  ? 125.054 91.957  104.114 1.00 56.06  ? 921  TRP A O   1 
ATOM   6318 C CB  . TRP A 1 962  ? 127.102 89.995  102.504 1.00 56.06  ? 921  TRP A CB  1 
ATOM   6319 C CG  . TRP A 1 962  ? 127.518 88.671  103.059 1.00 56.06  ? 921  TRP A CG  1 
ATOM   6320 C CD1 . TRP A 1 962  ? 126.707 87.610  103.329 1.00 56.06  ? 921  TRP A CD1 1 
ATOM   6321 C CD2 . TRP A 1 962  ? 128.845 88.263  103.411 1.00 56.06  ? 921  TRP A CD2 1 
ATOM   6322 N NE1 . TRP A 1 962  ? 127.444 86.566  103.828 1.00 56.06  ? 921  TRP A NE1 1 
ATOM   6323 C CE2 . TRP A 1 962  ? 128.761 86.941  103.890 1.00 56.06  ? 921  TRP A CE2 1 
ATOM   6324 C CE3 . TRP A 1 962  ? 130.096 88.888  103.369 1.00 56.06  ? 921  TRP A CE3 1 
ATOM   6325 C CZ2 . TRP A 1 962  ? 129.880 86.231  104.322 1.00 56.06  ? 921  TRP A CZ2 1 
ATOM   6326 C CZ3 . TRP A 1 962  ? 131.206 88.181  103.800 1.00 56.06  ? 921  TRP A CZ3 1 
ATOM   6327 C CH2 . TRP A 1 962  ? 131.090 86.866  104.270 1.00 56.06  ? 921  TRP A CH2 1 
ATOM   6328 N N   . LYS A 1 963  ? 125.191 92.540  101.945 1.00 54.30  ? 922  LYS A N   1 
ATOM   6329 C CA  . LYS A 1 963  ? 124.826 93.925  102.210 1.00 54.30  ? 922  LYS A CA  1 
ATOM   6330 C C   . LYS A 1 963  ? 123.413 94.017  102.763 1.00 54.30  ? 922  LYS A C   1 
ATOM   6331 O O   . LYS A 1 963  ? 123.151 94.771  103.707 1.00 54.30  ? 922  LYS A O   1 
ATOM   6332 C CB  . LYS A 1 963  ? 124.959 94.745  100.927 1.00 54.30  ? 922  LYS A CB  1 
ATOM   6333 C CG  . LYS A 1 963  ? 124.660 96.222  101.080 1.00 54.30  ? 922  LYS A CG  1 
ATOM   6334 C CD  . LYS A 1 963  ? 125.639 96.884  102.031 1.00 54.30  ? 922  LYS A CD  1 
ATOM   6335 C CE  . LYS A 1 963  ? 125.469 98.392  102.032 1.00 54.30  ? 922  LYS A CE  1 
ATOM   6336 N NZ  . LYS A 1 963  ? 125.717 98.972  100.683 1.00 54.30  ? 922  LYS A NZ  1 
ATOM   6337 N N   . GLY A 1 964  ? 122.486 93.251  102.188 1.00 50.06  ? 923  GLY A N   1 
ATOM   6338 C CA  . GLY A 1 964  ? 121.130 93.242  102.708 1.00 50.06  ? 923  GLY A CA  1 
ATOM   6339 C C   . GLY A 1 964  ? 121.064 92.724  104.130 1.00 50.06  ? 923  GLY A C   1 
ATOM   6340 O O   . GLY A 1 964  ? 120.367 93.287  104.977 1.00 50.06  ? 923  GLY A O   1 
ATOM   6341 N N   . GLN A 1 965  ? 121.801 91.647  104.415 1.00 48.43  ? 924  GLN A N   1 
ATOM   6342 C CA  . GLN A 1 965  ? 121.810 91.109  105.773 1.00 48.43  ? 924  GLN A CA  1 
ATOM   6343 C C   . GLN A 1 965  ? 122.335 92.137  106.769 1.00 48.43  ? 924  GLN A C   1 
ATOM   6344 O O   . GLN A 1 965  ? 121.724 92.371  107.821 1.00 48.43  ? 924  GLN A O   1 
ATOM   6345 C CB  . GLN A 1 965  ? 122.651 89.836  105.830 1.00 48.43  ? 924  GLN A CB  1 
ATOM   6346 C CG  . GLN A 1 965  ? 121.986 88.624  105.220 1.00 48.43  ? 924  GLN A CG  1 
ATOM   6347 C CD  . GLN A 1 965  ? 120.643 88.327  105.839 1.00 48.43  ? 924  GLN A CD  1 
ATOM   6348 O OE1 . GLN A 1 965  ? 120.504 88.290  107.058 1.00 48.43  ? 924  GLN A OE1 1 
ATOM   6349 N NE2 . GLN A 1 965  ? 119.643 88.102  104.999 1.00 48.43  ? 924  GLN A NE2 1 
ATOM   6350 N N   . ILE A 1 966  ? 123.464 92.771  106.446 1.00 47.17  ? 925  ILE A N   1 
ATOM   6351 C CA  . ILE A 1 966  ? 124.063 93.741  107.360 1.00 47.17  ? 925  ILE A CA  1 
ATOM   6352 C C   . ILE A 1 966  ? 123.136 94.933  107.560 1.00 47.17  ? 925  ILE A C   1 
ATOM   6353 O O   . ILE A 1 966  ? 122.937 95.402  108.687 1.00 47.17  ? 925  ILE A O   1 
ATOM   6354 C CB  . ILE A 1 966  ? 125.445 94.183  106.849 1.00 47.17  ? 925  ILE A CB  1 
ATOM   6355 C CG1 . ILE A 1 966  ? 126.408 92.998  106.834 1.00 47.17  ? 925  ILE A CG1 1 
ATOM   6356 C CG2 . ILE A 1 966  ? 125.996 95.300  107.709 1.00 47.17  ? 925  ILE A CG2 1 
ATOM   6357 C CD1 . ILE A 1 966  ? 126.562 92.330  108.176 1.00 47.17  ? 925  ILE A CD1 1 
ATOM   6358 N N   . ALA A 1 967  ? 122.558 95.445  106.471 1.00 46.08  ? 926  ALA A N   1 
ATOM   6359 C CA  . ALA A 1 967  ? 121.680 96.604  106.578 1.00 46.08  ? 926  ALA A CA  1 
ATOM   6360 C C   . ALA A 1 967  ? 120.451 96.289  107.420 1.00 46.08  ? 926  ALA A C   1 
ATOM   6361 O O   . ALA A 1 967  ? 120.061 97.077  108.289 1.00 46.08  ? 926  ALA A O   1 
ATOM   6362 C CB  . ALA A 1 967  ? 121.271 97.082  105.186 1.00 46.08  ? 926  ALA A CB  1 
ATOM   6363 N N   . GLY A 1 968  ? 119.830 95.132  107.182 1.00 46.12  ? 927  GLY A N   1 
ATOM   6364 C CA  . GLY A 1 968  ? 118.658 94.766  107.961 1.00 46.12  ? 927  GLY A CA  1 
ATOM   6365 C C   . GLY A 1 968  ? 118.975 94.603  109.433 1.00 46.12  ? 927  GLY A C   1 
ATOM   6366 O O   . GLY A 1 968  ? 118.250 95.108  110.297 1.00 46.12  ? 927  GLY A O   1 
ATOM   6367 N N   . SER A 1 969  ? 120.074 93.911  109.741 1.00 46.02  ? 928  SER A N   1 
ATOM   6368 C CA  . SER A 1 969  ? 120.449 93.711  111.137 1.00 46.02  ? 928  SER A CA  1 
ATOM   6369 C C   . SER A 1 969  ? 120.730 95.040  111.825 1.00 46.02  ? 928  SER A C   1 
ATOM   6370 O O   . SER A 1 969  ? 120.270 95.279  112.948 1.00 46.02  ? 928  SER A O   1 
ATOM   6371 C CB  . SER A 1 969  ? 121.663 92.789  111.223 1.00 46.02  ? 928  SER A CB  1 
ATOM   6372 O OG  . SER A 1 969  ? 122.002 92.525  112.570 1.00 46.02  ? 928  SER A OG  1 
ATOM   6373 N N   . GLY A 1 970  ? 121.472 95.927  111.160 1.00 45.49  ? 929  GLY A N   1 
ATOM   6374 C CA  . GLY A 1 970  ? 121.792 97.207  111.768 1.00 45.49  ? 929  GLY A CA  1 
ATOM   6375 C C   . GLY A 1 970  ? 120.564 98.064  112.002 1.00 45.49  ? 929  GLY A C   1 
ATOM   6376 O O   . GLY A 1 970  ? 120.399 98.657  113.073 1.00 45.49  ? 929  GLY A O   1 
ATOM   6377 N N   . TYR A 1 971  ? 119.680 98.140  111.004 1.00 42.68  ? 930  TYR A N   1 
ATOM   6378 C CA  . TYR A 1 971  ? 118.467 98.934  111.159 1.00 42.68  ? 930  TYR A CA  1 
ATOM   6379 C C   . TYR A 1 971  ? 117.601 98.392  112.290 1.00 42.68  ? 930  TYR A C   1 
ATOM   6380 O O   . TYR A 1 971  ? 117.079 99.158  113.112 1.00 42.68  ? 930  TYR A O   1 
ATOM   6381 C CB  . TYR A 1 971  ? 117.688 98.951  109.848 1.00 42.68  ? 930  TYR A CB  1 
ATOM   6382 C CG  . TYR A 1 971  ? 116.483 99.853  109.866 1.00 42.68  ? 930  TYR A CG  1 
ATOM   6383 C CD1 . TYR A 1 971  ? 116.623 101.228 109.817 1.00 42.68  ? 930  TYR A CD1 1 
ATOM   6384 C CD2 . TYR A 1 971  ? 115.207 99.330  109.948 1.00 42.68  ? 930  TYR A CD2 1 
ATOM   6385 C CE1 . TYR A 1 971  ? 115.521 102.054 109.835 1.00 42.68  ? 930  TYR A CE1 1 
ATOM   6386 C CE2 . TYR A 1 971  ? 114.100 100.147 109.968 1.00 42.68  ? 930  TYR A CE2 1 
ATOM   6387 C CZ  . TYR A 1 971  ? 114.262 101.507 109.912 1.00 42.68  ? 930  TYR A CZ  1 
ATOM   6388 O OH  . TYR A 1 971  ? 113.158 102.322 109.932 1.00 42.68  ? 930  TYR A OH  1 
ATOM   6389 N N   . GLY A 1 972  ? 117.446 97.069  112.352 1.00 42.57  ? 931  GLY A N   1 
ATOM   6390 C CA  . GLY A 1 972  ? 116.644 96.488  113.414 1.00 42.57  ? 931  GLY A CA  1 
ATOM   6391 C C   . GLY A 1 972  ? 117.225 96.749  114.789 1.00 42.57  ? 931  GLY A C   1 
ATOM   6392 O O   . GLY A 1 972  ? 116.499 97.073  115.732 1.00 42.57  ? 931  GLY A O   1 
ATOM   6393 N N   . VAL A 1 973  ? 118.546 96.614  114.922 1.00 42.89  ? 932  VAL A N   1 
ATOM   6394 C CA  . VAL A 1 973  ? 119.190 96.870  116.208 1.00 42.89  ? 932  VAL A CA  1 
ATOM   6395 C C   . VAL A 1 973  ? 118.993 98.322  116.617 1.00 42.89  ? 932  VAL A C   1 
ATOM   6396 O O   . VAL A 1 973  ? 118.713 98.625  117.782 1.00 42.89  ? 932  VAL A O   1 
ATOM   6397 C CB  . VAL A 1 973  ? 120.681 96.498  116.149 1.00 42.89  ? 932  VAL A CB  1 
ATOM   6398 C CG1 . VAL A 1 973  ? 121.419 97.079  117.335 1.00 42.89  ? 932  VAL A CG1 1 
ATOM   6399 C CG2 . VAL A 1 973  ? 120.843 94.998  116.128 1.00 42.89  ? 932  VAL A CG2 1 
ATOM   6400 N N   . ALA A 1 974  ? 119.137 99.244  115.663 1.00 41.90  ? 933  ALA A N   1 
ATOM   6401 C CA  . ALA A 1 974  ? 118.967 100.658 115.977 1.00 41.90  ? 933  ALA A CA  1 
ATOM   6402 C C   . ALA A 1 974  ? 117.550 100.952 116.455 1.00 41.90  ? 933  ALA A C   1 
ATOM   6403 O O   . ALA A 1 974  ? 117.351 101.669 117.442 1.00 41.90  ? 933  ALA A O   1 
ATOM   6404 C CB  . ALA A 1 974  ? 119.314 101.510 114.759 1.00 41.90  ? 933  ALA A CB  1 
ATOM   6405 N N   . GLN A 1 975  ? 116.546 100.401 115.770 1.00 43.22  ? 934  GLN A N   1 
ATOM   6406 C CA  . GLN A 1 975  ? 115.167 100.640 116.188 1.00 43.22  ? 934  GLN A CA  1 
ATOM   6407 C C   . GLN A 1 975  ? 114.884 100.028 117.555 1.00 43.22  ? 934  GLN A C   1 
ATOM   6408 O O   . GLN A 1 975  ? 114.189 100.630 118.388 1.00 43.22  ? 934  GLN A O   1 
ATOM   6409 C CB  . GLN A 1 975  ? 114.199 100.092 115.144 1.00 43.22  ? 934  GLN A CB  1 
ATOM   6410 C CG  . GLN A 1 975  ? 114.395 100.675 113.766 1.00 43.22  ? 934  GLN A CG  1 
ATOM   6411 C CD  . GLN A 1 975  ? 114.513 102.179 113.789 1.00 43.22  ? 934  GLN A CD  1 
ATOM   6412 O OE1 . GLN A 1 975  ? 115.556 102.736 113.452 1.00 43.22  ? 934  GLN A OE1 1 
ATOM   6413 N NE2 . GLN A 1 975  ? 113.439 102.847 114.183 1.00 43.22  ? 934  GLN A NE2 1 
ATOM   6414 N N   . PHE A 1 976  ? 115.410 98.827  117.805 1.00 42.89  ? 935  PHE A N   1 
ATOM   6415 C CA  . PHE A 1 976  ? 115.217 98.200  119.107 1.00 42.89  ? 935  PHE A CA  1 
ATOM   6416 C C   . PHE A 1 976  ? 115.839 99.040  120.212 1.00 42.89  ? 935  PHE A C   1 
ATOM   6417 O O   . PHE A 1 976  ? 115.247 99.208  121.282 1.00 42.89  ? 935  PHE A O   1 
ATOM   6418 C CB  . PHE A 1 976  ? 115.813 96.796  119.114 1.00 42.89  ? 935  PHE A CB  1 
ATOM   6419 C CG  . PHE A 1 976  ? 115.743 96.125  120.449 1.00 42.89  ? 935  PHE A CG  1 
ATOM   6420 C CD1 . PHE A 1 976  ? 114.528 95.720  120.969 1.00 42.89  ? 935  PHE A CD1 1 
ATOM   6421 C CD2 . PHE A 1 976  ? 116.887 95.920  121.197 1.00 42.89  ? 935  PHE A CD2 1 
ATOM   6422 C CE1 . PHE A 1 976  ? 114.458 95.106  122.197 1.00 42.89  ? 935  PHE A CE1 1 
ATOM   6423 C CE2 . PHE A 1 976  ? 116.821 95.309  122.429 1.00 42.89  ? 935  PHE A CE2 1 
ATOM   6424 C CZ  . PHE A 1 976  ? 115.606 94.903  122.930 1.00 42.89  ? 935  PHE A CZ  1 
ATOM   6425 N N   . CYS A 1 977  ? 117.040 99.571  119.974 1.00 43.28  ? 936  CYS A N   1 
ATOM   6426 C CA  . CYS A 1 977  ? 117.675 100.426 120.970 1.00 43.28  ? 936  CYS A CA  1 
ATOM   6427 C C   . CYS A 1 977  ? 116.879 101.705 121.185 1.00 43.28  ? 936  CYS A C   1 
ATOM   6428 O O   . CYS A 1 977  ? 116.781 102.199 122.311 1.00 43.28  ? 936  CYS A O   1 
ATOM   6429 C CB  . CYS A 1 977  ? 119.110 100.745 120.560 1.00 43.28  ? 936  CYS A CB  1 
ATOM   6430 S SG  . CYS A 1 977  ? 120.216 99.321  120.587 1.00 43.28  ? 936  CYS A SG  1 
ATOM   6431 N N   . LEU A 1 978  ? 116.300 102.254 120.115 1.00 43.13  ? 937  LEU A N   1 
ATOM   6432 C CA  . LEU A 1 978  ? 115.447 103.432 120.254 1.00 43.13  ? 937  LEU A CA  1 
ATOM   6433 C C   . LEU A 1 978  ? 114.279 103.160 121.194 1.00 43.13  ? 937  LEU A C   1 
ATOM   6434 O O   . LEU A 1 978  ? 114.017 103.931 122.127 1.00 43.13  ? 937  LEU A O   1 
ATOM   6435 C CB  . LEU A 1 978  ? 114.930 103.860 118.883 1.00 43.13  ? 937  LEU A CB  1 
ATOM   6436 C CG  . LEU A 1 978  ? 113.855 104.942 118.872 1.00 43.13  ? 937  LEU A CG  1 
ATOM   6437 C CD1 . LEU A 1 978  ? 114.401 106.208 119.473 1.00 43.13  ? 937  LEU A CD1 1 
ATOM   6438 C CD2 . LEU A 1 978  ? 113.358 105.189 117.465 1.00 43.13  ? 937  LEU A CD2 1 
ATOM   6439 N N   . TYR A 1 979  ? 113.562 102.061 120.962 1.00 42.25  ? 938  TYR A N   1 
ATOM   6440 C CA  . TYR A 1 979  ? 112.390 101.789 121.789 1.00 42.25  ? 938  TYR A CA  1 
ATOM   6441 C C   . TYR A 1 979  ? 112.785 101.375 123.201 1.00 42.25  ? 938  TYR A C   1 
ATOM   6442 O O   . TYR A 1 979  ? 112.068 101.672 124.164 1.00 42.25  ? 938  TYR A O   1 
ATOM   6443 C CB  . TYR A 1 979  ? 111.512 100.741 121.117 1.00 42.25  ? 938  TYR A CB  1 
ATOM   6444 C CG  . TYR A 1 979  ? 110.811 101.315 119.917 1.00 42.25  ? 938  TYR A CG  1 
ATOM   6445 C CD1 . TYR A 1 979  ? 109.899 102.343 120.061 1.00 42.25  ? 938  TYR A CD1 1 
ATOM   6446 C CD2 . TYR A 1 979  ? 111.097 100.869 118.639 1.00 42.25  ? 938  TYR A CD2 1 
ATOM   6447 C CE1 . TYR A 1 979  ? 109.268 102.889 118.973 1.00 42.25  ? 938  TYR A CE1 1 
ATOM   6448 C CE2 . TYR A 1 979  ? 110.470 101.412 117.542 1.00 42.25  ? 938  TYR A CE2 1 
ATOM   6449 C CZ  . TYR A 1 979  ? 109.557 102.422 117.717 1.00 42.25  ? 938  TYR A CZ  1 
ATOM   6450 O OH  . TYR A 1 979  ? 108.926 102.971 116.630 1.00 42.25  ? 938  TYR A OH  1 
ATOM   6451 N N   . ALA A 1 980  ? 113.935 100.718 123.354 1.00 43.60  ? 939  ALA A N   1 
ATOM   6452 C CA  . ALA A 1 980  ? 114.436 100.416 124.689 1.00 43.60  ? 939  ALA A CA  1 
ATOM   6453 C C   . ALA A 1 980  ? 114.765 101.694 125.447 1.00 43.60  ? 939  ALA A C   1 
ATOM   6454 O O   . ALA A 1 980  ? 114.522 101.792 126.652 1.00 43.60  ? 939  ALA A O   1 
ATOM   6455 C CB  . ALA A 1 980  ? 115.661 99.509  124.599 1.00 43.60  ? 939  ALA A CB  1 
ATOM   6456 N N   . SER A 1 981  ? 115.330 102.686 124.755 1.00 44.60  ? 940  SER A N   1 
ATOM   6457 C CA  . SER A 1 981  ? 115.610 103.965 125.395 1.00 44.60  ? 940  SER A CA  1 
ATOM   6458 C C   . SER A 1 981  ? 114.325 104.674 125.797 1.00 44.60  ? 940  SER A C   1 
ATOM   6459 O O   . SER A 1 981  ? 114.246 105.257 126.885 1.00 44.60  ? 940  SER A O   1 
ATOM   6460 C CB  . SER A 1 981  ? 116.436 104.850 124.464 1.00 44.60  ? 940  SER A CB  1 
ATOM   6461 O OG  . SER A 1 981  ? 115.671 105.251 123.343 1.00 44.60  ? 940  SER A OG  1 
ATOM   6462 N N   . TYR A 1 982  ? 113.309 104.645 124.931 1.00 44.41  ? 941  TYR A N   1 
ATOM   6463 C CA  . TYR A 1 982  ? 112.013 105.210 125.304 1.00 44.41  ? 941  TYR A CA  1 
ATOM   6464 C C   . TYR A 1 982  ? 111.478 104.549 126.567 1.00 44.41  ? 941  TYR A C   1 
ATOM   6465 O O   . TYR A 1 982  ? 111.062 105.230 127.515 1.00 44.41  ? 941  TYR A O   1 
ATOM   6466 C CB  . TYR A 1 982  ? 111.006 105.045 124.166 1.00 44.41  ? 941  TYR A CB  1 
ATOM   6467 C CG  . TYR A 1 982  ? 111.173 106.009 123.022 1.00 44.41  ? 941  TYR A CG  1 
ATOM   6468 C CD1 . TYR A 1 982  ? 112.065 107.062 123.099 1.00 44.41  ? 941  TYR A CD1 1 
ATOM   6469 C CD2 . TYR A 1 982  ? 110.440 105.860 121.860 1.00 44.41  ? 941  TYR A CD2 1 
ATOM   6470 C CE1 . TYR A 1 982  ? 112.218 107.943 122.052 1.00 44.41  ? 941  TYR A CE1 1 
ATOM   6471 C CE2 . TYR A 1 982  ? 110.586 106.732 120.809 1.00 44.41  ? 941  TYR A CE2 1 
ATOM   6472 C CZ  . TYR A 1 982  ? 111.477 107.772 120.909 1.00 44.41  ? 941  TYR A CZ  1 
ATOM   6473 O OH  . TYR A 1 982  ? 111.623 108.646 119.858 1.00 44.41  ? 941  TYR A OH  1 
ATOM   6474 N N   . ALA A 1 983  ? 111.490 103.215 126.597 1.00 42.85  ? 942  ALA A N   1 
ATOM   6475 C CA  . ALA A 1 983  ? 110.961 102.492 127.746 1.00 42.85  ? 942  ALA A CA  1 
ATOM   6476 C C   . ALA A 1 983  ? 111.747 102.814 129.008 1.00 42.85  ? 942  ALA A C   1 
ATOM   6477 O O   . ALA A 1 983  ? 111.164 103.051 130.070 1.00 42.85  ? 942  ALA A O   1 
ATOM   6478 C CB  . ALA A 1 983  ? 110.976 100.990 127.472 1.00 42.85  ? 942  ALA A CB  1 
ATOM   6479 N N   . LEU A 1 984  ? 113.078 102.836 128.909 1.00 45.59  ? 943  LEU A N   1 
ATOM   6480 C CA  . LEU A 1 984  ? 113.906 103.111 130.077 1.00 45.59  ? 943  LEU A CA  1 
ATOM   6481 C C   . LEU A 1 984  ? 113.663 104.513 130.611 1.00 45.59  ? 943  LEU A C   1 
ATOM   6482 O O   . LEU A 1 984  ? 113.509 104.709 131.821 1.00 45.59  ? 943  LEU A O   1 
ATOM   6483 C CB  . LEU A 1 984  ? 115.380 102.924 129.731 1.00 45.59  ? 943  LEU A CB  1 
ATOM   6484 C CG  . LEU A 1 984  ? 116.350 103.539 130.738 1.00 45.59  ? 943  LEU A CG  1 
ATOM   6485 C CD1 . LEU A 1 984  ? 116.402 102.699 132.000 1.00 45.59  ? 943  LEU A CD1 1 
ATOM   6486 C CD2 . LEU A 1 984  ? 117.734 103.691 130.131 1.00 45.59  ? 943  LEU A CD2 1 
ATOM   6487 N N   . GLY A 1 985  ? 113.619 105.506 129.723 1.00 50.54  ? 944  GLY A N   1 
ATOM   6488 C CA  . GLY A 1 985  ? 113.394 106.867 130.175 1.00 50.54  ? 944  GLY A CA  1 
ATOM   6489 C C   . GLY A 1 985  ? 112.040 107.047 130.828 1.00 50.54  ? 944  GLY A C   1 
ATOM   6490 O O   . GLY A 1 985  ? 111.923 107.685 131.879 1.00 50.54  ? 944  GLY A O   1 
ATOM   6491 N N   . LEU A 1 986  ? 111.000 106.464 130.233 1.00 44.72  ? 945  LEU A N   1 
ATOM   6492 C CA  . LEU A 1 986  ? 109.662 106.656 130.778 1.00 44.72  ? 945  LEU A CA  1 
ATOM   6493 C C   . LEU A 1 986  ? 109.490 105.890 132.087 1.00 44.72  ? 945  LEU A C   1 
ATOM   6494 O O   . LEU A 1 986  ? 108.847 106.378 133.027 1.00 44.72  ? 945  LEU A O   1 
ATOM   6495 C CB  . LEU A 1 986  ? 108.632 106.239 129.732 1.00 44.72  ? 945  LEU A CB  1 
ATOM   6496 C CG  . LEU A 1 986  ? 107.285 106.948 129.746 1.00 44.72  ? 945  LEU A CG  1 
ATOM   6497 C CD1 . LEU A 1 986  ? 107.499 108.436 129.862 1.00 44.72  ? 945  LEU A CD1 1 
ATOM   6498 C CD2 . LEU A 1 986  ? 106.568 106.645 128.450 1.00 44.72  ? 945  LEU A CD2 1 
ATOM   6499 N N   . TRP A 1 987  ? 110.100 104.707 132.189 1.00 45.91  ? 946  TRP A N   1 
ATOM   6500 C CA  . TRP A 1 987  ? 110.085 103.980 133.450 1.00 45.91  ? 946  TRP A CA  1 
ATOM   6501 C C   . TRP A 1 987  ? 110.841 104.735 134.533 1.00 45.91  ? 946  TRP A C   1 
ATOM   6502 O O   . TRP A 1 987  ? 110.433 104.730 135.697 1.00 45.91  ? 946  TRP A O   1 
ATOM   6503 C CB  . TRP A 1 987  ? 110.681 102.586 133.273 1.00 45.91  ? 946  TRP A CB  1 
ATOM   6504 C CG  . TRP A 1 987  ? 110.921 101.896 134.577 1.00 45.91  ? 946  TRP A CG  1 
ATOM   6505 C CD1 . TRP A 1 987  ? 110.044 101.109 135.260 1.00 45.91  ? 946  TRP A CD1 1 
ATOM   6506 C CD2 . TRP A 1 987  ? 112.110 101.954 135.372 1.00 45.91  ? 946  TRP A CD2 1 
ATOM   6507 N NE1 . TRP A 1 987  ? 110.616 100.661 136.425 1.00 45.91  ? 946  TRP A NE1 1 
ATOM   6508 C CE2 . TRP A 1 987  ? 111.885 101.169 136.518 1.00 45.91  ? 946  TRP A CE2 1 
ATOM   6509 C CE3 . TRP A 1 987  ? 113.343 102.592 135.225 1.00 45.91  ? 946  TRP A CE3 1 
ATOM   6510 C CZ2 . TRP A 1 987  ? 112.846 101.003 137.506 1.00 45.91  ? 946  TRP A CZ2 1 
ATOM   6511 C CZ3 . TRP A 1 987  ? 114.295 102.427 136.208 1.00 45.91  ? 946  TRP A CZ3 1 
ATOM   6512 C CH2 . TRP A 1 987  ? 114.043 101.639 137.333 1.00 45.91  ? 946  TRP A CH2 1 
ATOM   6513 N N   . TYR A 1 988  ? 111.963 105.364 134.182 1.00 45.28  ? 947  TYR A N   1 
ATOM   6514 C CA  . TYR A 1 988  ? 112.697 106.136 135.178 1.00 45.28  ? 947  TYR A CA  1 
ATOM   6515 C C   . TYR A 1 988  ? 111.898 107.347 135.630 1.00 45.28  ? 947  TYR A C   1 
ATOM   6516 O O   . TYR A 1 988  ? 111.961 107.740 136.799 1.00 45.28  ? 947  TYR A O   1 
ATOM   6517 C CB  . TYR A 1 988  ? 114.052 106.569 134.634 1.00 45.28  ? 947  TYR A CB  1 
ATOM   6518 C CG  . TYR A 1 988  ? 114.946 107.150 135.696 1.00 45.28  ? 947  TYR A CG  1 
ATOM   6519 C CD1 . TYR A 1 988  ? 115.323 106.396 136.794 1.00 45.28  ? 947  TYR A CD1 1 
ATOM   6520 C CD2 . TYR A 1 988  ? 115.403 108.452 135.609 1.00 45.28  ? 947  TYR A CD2 1 
ATOM   6521 C CE1 . TYR A 1 988  ? 116.136 106.920 137.770 1.00 45.28  ? 947  TYR A CE1 1 
ATOM   6522 C CE2 . TYR A 1 988  ? 116.216 108.985 136.582 1.00 45.28  ? 947  TYR A CE2 1 
ATOM   6523 C CZ  . TYR A 1 988  ? 116.579 108.215 137.660 1.00 45.28  ? 947  TYR A CZ  1 
ATOM   6524 O OH  . TYR A 1 988  ? 117.391 108.740 138.634 1.00 45.28  ? 947  TYR A OH  1 
ATOM   6525 N N   . ALA A 1 989  ? 111.150 107.962 134.715 1.00 43.92  ? 948  ALA A N   1 
ATOM   6526 C CA  . ALA A 1 989  ? 110.242 109.032 135.114 1.00 43.92  ? 948  ALA A CA  1 
ATOM   6527 C C   . ALA A 1 989  ? 109.219 108.522 136.119 1.00 43.92  ? 948  ALA A C   1 
ATOM   6528 O O   . ALA A 1 989  ? 108.944 109.172 137.137 1.00 43.92  ? 948  ALA A O   1 
ATOM   6529 C CB  . ALA A 1 989  ? 109.545 109.616 133.887 1.00 43.92  ? 948  ALA A CB  1 
ATOM   6530 N N   . SER A 1 990  ? 108.655 107.344 135.853 1.00 48.22  ? 949  SER A N   1 
ATOM   6531 C CA  . SER A 1 990  ? 107.707 106.756 136.795 1.00 48.22  ? 949  SER A CA  1 
ATOM   6532 C C   . SER A 1 990  ? 108.362 106.474 138.141 1.00 48.22  ? 949  SER A C   1 
ATOM   6533 O O   . SER A 1 990  ? 107.746 106.671 139.193 1.00 48.22  ? 949  SER A O   1 
ATOM   6534 C CB  . SER A 1 990  ? 107.118 105.476 136.215 1.00 48.22  ? 949  SER A CB  1 
ATOM   6535 O OG  . SER A 1 990  ? 106.334 104.804 137.180 1.00 48.22  ? 949  SER A OG  1 
ATOM   6536 N N   . TRP A 1 991  ? 109.603 105.993 138.125 1.00 49.35  ? 950  TRP A N   1 
ATOM   6537 C CA  . TRP A 1 991  ? 110.314 105.698 139.366 1.00 49.35  ? 950  TRP A CA  1 
ATOM   6538 C C   . TRP A 1 991  ? 110.571 106.967 140.167 1.00 49.35  ? 950  TRP A C   1 
ATOM   6539 O O   . TRP A 1 991  ? 110.473 106.969 141.399 1.00 49.35  ? 950  TRP A O   1 
ATOM   6540 C CB  . TRP A 1 991  ? 111.628 104.989 139.050 1.00 49.35  ? 950  TRP A CB  1 
ATOM   6541 C CG  . TRP A 1 991  ? 112.332 104.447 140.245 1.00 49.35  ? 950  TRP A CG  1 
ATOM   6542 C CD1 . TRP A 1 991  ? 112.109 103.248 140.850 1.00 49.35  ? 950  TRP A CD1 1 
ATOM   6543 C CD2 . TRP A 1 991  ? 113.381 105.082 140.980 1.00 49.35  ? 950  TRP A CD2 1 
ATOM   6544 N NE1 . TRP A 1 991  ? 112.956 103.095 141.919 1.00 49.35  ? 950  TRP A NE1 1 
ATOM   6545 C CE2 . TRP A 1 991  ? 113.747 104.208 142.020 1.00 49.35  ? 950  TRP A CE2 1 
ATOM   6546 C CE3 . TRP A 1 991  ? 114.047 106.304 140.861 1.00 49.35  ? 950  TRP A CE3 1 
ATOM   6547 C CZ2 . TRP A 1 991  ? 114.747 104.519 142.937 1.00 49.35  ? 950  TRP A CZ2 1 
ATOM   6548 C CZ3 . TRP A 1 991  ? 115.040 106.611 141.771 1.00 49.35  ? 950  TRP A CZ3 1 
ATOM   6549 C CH2 . TRP A 1 991  ? 115.381 105.722 142.796 1.00 49.35  ? 950  TRP A CH2 1 
ATOM   6550 N N   . LEU A 1 992  ? 110.920 108.057 139.482 1.00 48.80  ? 951  LEU A N   1 
ATOM   6551 C CA  . LEU A 1 992  ? 111.102 109.335 140.162 1.00 48.80  ? 951  LEU A CA  1 
ATOM   6552 C C   . LEU A 1 992  ? 109.800 109.810 140.788 1.00 48.80  ? 951  LEU A C   1 
ATOM   6553 O O   . LEU A 1 992  ? 109.787 110.311 141.918 1.00 48.80  ? 951  LEU A O   1 
ATOM   6554 C CB  . LEU A 1 992  ? 111.634 110.384 139.187 1.00 48.80  ? 951  LEU A CB  1 
ATOM   6555 C CG  . LEU A 1 992  ? 113.078 110.237 138.724 1.00 48.80  ? 951  LEU A CG  1 
ATOM   6556 C CD1 . LEU A 1 992  ? 113.455 111.405 137.839 1.00 48.80  ? 951  LEU A CD1 1 
ATOM   6557 C CD2 . LEU A 1 992  ? 114.001 110.151 139.921 1.00 48.80  ? 951  LEU A CD2 1 
ATOM   6558 N N   . VAL A 1 993  ? 108.690 109.667 140.064 1.00 48.03  ? 952  VAL A N   1 
ATOM   6559 C CA  . VAL A 1 993  ? 107.403 110.083 140.616 1.00 48.03  ? 952  VAL A CA  1 
ATOM   6560 C C   . VAL A 1 993  ? 107.033 109.223 141.818 1.00 48.03  ? 952  VAL A C   1 
ATOM   6561 O O   . VAL A 1 993  ? 106.456 109.713 142.796 1.00 48.03  ? 952  VAL A O   1 
ATOM   6562 C CB  . VAL A 1 993  ? 106.315 110.046 139.531 1.00 48.03  ? 952  VAL A CB  1 
ATOM   6563 C CG1 . VAL A 1 993  ? 104.966 110.371 140.127 1.00 48.03  ? 952  VAL A CG1 1 
ATOM   6564 C CG2 . VAL A 1 993  ? 106.648 111.038 138.444 1.00 48.03  ? 952  VAL A CG2 1 
ATOM   6565 N N   . LYS A 1 994  ? 107.364 107.932 141.771 1.00 55.21  ? 953  LYS A N   1 
ATOM   6566 C CA  . LYS A 1 994  ? 106.997 107.032 142.861 1.00 55.21  ? 953  LYS A CA  1 
ATOM   6567 C C   . LYS A 1 994  ? 107.666 107.433 144.170 1.00 55.21  ? 953  LYS A C   1 
ATOM   6568 O O   . LYS A 1 994  ? 107.021 107.458 145.222 1.00 55.21  ? 953  LYS A O   1 
ATOM   6569 C CB  . LYS A 1 994  ? 107.357 105.592 142.501 1.00 55.21  ? 953  LYS A CB  1 
ATOM   6570 C CG  . LYS A 1 994  ? 107.320 104.633 143.678 1.00 55.21  ? 953  LYS A CG  1 
ATOM   6571 C CD  . LYS A 1 994  ? 107.992 103.315 143.348 1.00 55.21  ? 953  LYS A CD  1 
ATOM   6572 C CE  . LYS A 1 994  ? 107.860 102.325 144.491 1.00 55.21  ? 953  LYS A CE  1 
ATOM   6573 N NZ  . LYS A 1 994  ? 108.401 102.868 145.765 1.00 55.21  ? 953  LYS A NZ  1 
ATOM   6574 N N   . HIS A 1 995  ? 108.955 107.758 144.125 1.00 56.45  ? 954  HIS A N   1 
ATOM   6575 C CA  . HIS A 1 995  ? 109.697 108.106 145.328 1.00 56.45  ? 954  HIS A CA  1 
ATOM   6576 C C   . HIS A 1 995  ? 109.534 109.564 145.728 1.00 56.45  ? 954  HIS A C   1 
ATOM   6577 O O   . HIS A 1 995  ? 110.334 110.067 146.524 1.00 56.45  ? 954  HIS A O   1 
ATOM   6578 C CB  . HIS A 1 995  ? 111.179 107.777 145.143 1.00 56.45  ? 954  HIS A CB  1 
ATOM   6579 C CG  . HIS A 1 995  ? 111.478 106.313 145.184 1.00 56.45  ? 954  HIS A CG  1 
ATOM   6580 N ND1 . HIS A 1 995  ? 112.346 105.756 146.097 1.00 56.45  ? 954  HIS A ND1 1 
ATOM   6581 C CD2 . HIS A 1 995  ? 111.018 105.288 144.427 1.00 56.45  ? 954  HIS A CD2 1 
ATOM   6582 C CE1 . HIS A 1 995  ? 112.411 104.451 145.899 1.00 56.45  ? 954  HIS A CE1 1 
ATOM   6583 N NE2 . HIS A 1 995  ? 111.615 104.142 144.892 1.00 56.45  ? 954  HIS A NE2 1 
ATOM   6584 N N   . GLY A 1 996  ? 108.531 110.255 145.197 1.00 51.92  ? 955  GLY A N   1 
ATOM   6585 C CA  . GLY A 1 996  ? 108.260 111.623 145.587 1.00 51.92  ? 955  GLY A CA  1 
ATOM   6586 C C   . GLY A 1 996  ? 109.315 112.608 145.133 1.00 51.92  ? 955  GLY A C   1 
ATOM   6587 O O   . GLY A 1 996  ? 109.319 113.764 145.562 1.00 51.92  ? 955  GLY A O   1 
ATOM   6588 N N   . ILE A 1 997  ? 110.220 112.159 144.263 1.00 50.47  ? 956  ILE A N   1 
ATOM   6589 C CA  . ILE A 1 997  ? 111.281 113.035 143.781 1.00 50.47  ? 956  ILE A CA  1 
ATOM   6590 C C   . ILE A 1 997  ? 110.707 114.151 142.920 1.00 50.47  ? 956  ILE A C   1 
ATOM   6591 O O   . ILE A 1 997  ? 111.112 115.313 143.037 1.00 50.47  ? 956  ILE A O   1 
ATOM   6592 C CB  . ILE A 1 997  ? 112.338 112.223 143.015 1.00 50.47  ? 956  ILE A CB  1 
ATOM   6593 C CG1 . ILE A 1 997  ? 112.940 111.139 143.911 1.00 50.47  ? 956  ILE A CG1 1 
ATOM   6594 C CG2 . ILE A 1 997  ? 113.413 113.142 142.476 1.00 50.47  ? 956  ILE A CG2 1 
ATOM   6595 C CD1 . ILE A 1 997  ? 114.059 111.628 144.796 1.00 50.47  ? 956  ILE A CD1 1 
ATOM   6596 N N   . SER A 1 998  ? 109.758 113.825 142.047 1.00 53.19  ? 957  SER A N   1 
ATOM   6597 C CA  . SER A 1 998  ? 109.224 114.792 141.102 1.00 53.19  ? 957  SER A CA  1 
ATOM   6598 C C   . SER A 1 998  ? 107.726 114.563 140.952 1.00 53.19  ? 957  SER A C   1 
ATOM   6599 O O   . SER A 1 998  ? 107.100 113.851 141.742 1.00 53.19  ? 957  SER A O   1 
ATOM   6600 C CB  . SER A 1 998  ? 109.947 114.693 139.755 1.00 53.19  ? 957  SER A CB  1 
ATOM   6601 O OG  . SER A 1 998  ? 109.227 115.382 138.750 1.00 53.19  ? 957  SER A OG  1 
ATOM   6602 N N   . ASP A 1 999  ? 107.154 115.185 139.930 1.00 52.47  ? 958  ASP A N   1 
ATOM   6603 C CA  . ASP A 1 999  ? 105.738 115.109 139.615 1.00 52.47  ? 958  ASP A CA  1 
ATOM   6604 C C   . ASP A 1 999  ? 105.563 114.480 138.239 1.00 52.47  ? 958  ASP A C   1 
ATOM   6605 O O   . ASP A 1 999  ? 106.523 114.302 137.487 1.00 52.47  ? 958  ASP A O   1 
ATOM   6606 C CB  . ASP A 1 999  ? 105.102 116.503 139.653 1.00 52.47  ? 958  ASP A CB  1 
ATOM   6607 C CG  . ASP A 1 999  ? 103.591 116.456 139.691 1.00 52.47  ? 958  ASP A CG  1 
ATOM   6608 O OD1 . ASP A 1 999  ? 103.031 115.342 139.728 1.00 52.47  ? 958  ASP A OD1 1 
ATOM   6609 O OD2 . ASP A 1 999  ? 102.963 117.536 139.677 1.00 52.47  ? 958  ASP A OD2 1 
ATOM   6610 N N   . PHE A 1 1000 ? 104.319 114.132 137.914 1.00 46.64  ? 959  PHE A N   1 
ATOM   6611 C CA  . PHE A 1 1000 ? 104.017 113.668 136.565 1.00 46.64  ? 959  PHE A CA  1 
ATOM   6612 C C   . PHE A 1 1000 ? 104.278 114.765 135.545 1.00 46.64  ? 959  PHE A C   1 
ATOM   6613 O O   . PHE A 1 1000 ? 104.824 114.511 134.466 1.00 46.64  ? 959  PHE A O   1 
ATOM   6614 C CB  . PHE A 1 1000 ? 102.566 113.203 136.477 1.00 46.64  ? 959  PHE A CB  1 
ATOM   6615 C CG  . PHE A 1 1000 ? 102.015 113.205 135.078 1.00 46.64  ? 959  PHE A CG  1 
ATOM   6616 C CD1 . PHE A 1 1000 ? 102.459 112.292 134.143 1.00 46.64  ? 959  PHE A CD1 1 
ATOM   6617 C CD2 . PHE A 1 1000 ? 101.059 114.125 134.698 1.00 46.64  ? 959  PHE A CD2 1 
ATOM   6618 C CE1 . PHE A 1 1000 ? 101.953 112.289 132.861 1.00 46.64  ? 959  PHE A CE1 1 
ATOM   6619 C CE2 . PHE A 1 1000 ? 100.552 114.126 133.416 1.00 46.64  ? 959  PHE A CE2 1 
ATOM   6620 C CZ  . PHE A 1 1000 ? 101.001 113.208 132.497 1.00 46.64  ? 959  PHE A CZ  1 
ATOM   6621 N N   . SER A 1 1001 ? 103.891 115.997 135.877 1.00 43.63  ? 960  SER A N   1 
ATOM   6622 C CA  . SER A 1 1001 ? 103.963 117.098 134.926 1.00 43.63  ? 960  SER A CA  1 
ATOM   6623 C C   . SER A 1 1001 ? 105.394 117.353 134.468 1.00 43.63  ? 960  SER A C   1 
ATOM   6624 O O   . SER A 1 1001 ? 105.687 117.372 133.266 1.00 43.63  ? 960  SER A O   1 
ATOM   6625 C CB  . SER A 1 1001 ? 103.370 118.353 135.568 1.00 43.63  ? 960  SER A CB  1 
ATOM   6626 O OG  . SER A 1 1001 ? 103.533 119.478 134.726 1.00 43.63  ? 960  SER A OG  1 
ATOM   6627 N N   . LYS A 1 1002 ? 106.304 117.530 135.425 1.00 42.56  ? 961  LYS A N   1 
ATOM   6628 C CA  . LYS A 1 1002 ? 107.681 117.871 135.089 1.00 42.56  ? 961  LYS A CA  1 
ATOM   6629 C C   . LYS A 1 1002 ? 108.363 116.739 134.332 1.00 42.56  ? 961  LYS A C   1 
ATOM   6630 O O   . LYS A 1 1002 ? 109.052 116.969 133.331 1.00 42.56  ? 961  LYS A O   1 
ATOM   6631 C CB  . LYS A 1 1002 ? 108.445 118.215 136.363 1.00 42.56  ? 961  LYS A CB  1 
ATOM   6632 C CG  . LYS A 1 1002 ? 107.986 119.509 136.997 1.00 42.56  ? 961  LYS A CG  1 
ATOM   6633 C CD  . LYS A 1 1002 ? 108.720 119.797 138.288 1.00 42.56  ? 961  LYS A CD  1 
ATOM   6634 C CE  . LYS A 1 1002 ? 108.370 121.180 138.803 1.00 42.56  ? 961  LYS A CE  1 
ATOM   6635 N NZ  . LYS A 1 1002 ? 106.900 121.356 138.950 1.00 42.56  ? 961  LYS A NZ  1 
ATOM   6636 N N   . THR A 1 1003 ? 108.174 115.503 134.795 1.00 39.38  ? 962  THR A N   1 
ATOM   6637 C CA  . THR A 1 1003 ? 108.821 114.363 134.154 1.00 39.38  ? 962  THR A CA  1 
ATOM   6638 C C   . THR A 1 1003 ? 108.310 114.163 132.734 1.00 39.38  ? 962  THR A C   1 
ATOM   6639 O O   . THR A 1 1003 ? 109.092 113.903 131.811 1.00 39.38  ? 962  THR A O   1 
ATOM   6640 C CB  . THR A 1 1003 ? 108.598 113.104 134.985 1.00 39.38  ? 962  THR A CB  1 
ATOM   6641 O OG1 . THR A 1 1003 ? 107.204 112.972 135.283 1.00 39.38  ? 962  THR A OG1 1 
ATOM   6642 C CG2 . THR A 1 1003 ? 109.379 113.183 136.278 1.00 39.38  ? 962  THR A CG2 1 
ATOM   6643 N N   . ILE A 1 1004 ? 106.995 114.274 132.535 1.00 40.83  ? 963  ILE A N   1 
ATOM   6644 C CA  . ILE A 1 1004 ? 106.453 114.069 131.197 1.00 40.83  ? 963  ILE A CA  1 
ATOM   6645 C C   . ILE A 1 1004 ? 106.892 115.194 130.271 1.00 40.83  ? 963  ILE A C   1 
ATOM   6646 O O   . ILE A 1 1004 ? 107.180 114.962 129.091 1.00 40.83  ? 963  ILE A O   1 
ATOM   6647 C CB  . ILE A 1 1004 ? 104.921 113.911 131.238 1.00 40.83  ? 963  ILE A CB  1 
ATOM   6648 C CG1 . ILE A 1 1004 ? 104.446 113.160 129.996 1.00 40.83  ? 963  ILE A CG1 1 
ATOM   6649 C CG2 . ILE A 1 1004 ? 104.218 115.249 131.314 1.00 40.83  ? 963  ILE A CG2 1 
ATOM   6650 C CD1 . ILE A 1 1004 ? 105.058 111.790 129.846 1.00 40.83  ? 963  ILE A CD1 1 
ATOM   6651 N N   . ARG A 1 1005 ? 106.977 116.423 130.788 1.00 36.86  ? 964  ARG A N   1 
ATOM   6652 C CA  . ARG A 1 1005 ? 107.461 117.520 129.960 1.00 36.86  ? 964  ARG A CA  1 
ATOM   6653 C C   . ARG A 1 1005 ? 108.905 117.288 129.543 1.00 36.86  ? 964  ARG A C   1 
ATOM   6654 O O   . ARG A 1 1005 ? 109.258 117.475 128.374 1.00 36.86  ? 964  ARG A O   1 
ATOM   6655 C CB  . ARG A 1 1005 ? 107.308 118.848 130.695 1.00 36.86  ? 964  ARG A CB  1 
ATOM   6656 C CG  . ARG A 1 1005 ? 105.960 119.506 130.482 1.00 36.86  ? 964  ARG A CG  1 
ATOM   6657 C CD  . ARG A 1 1005 ? 105.890 120.870 131.136 1.00 36.86  ? 964  ARG A CD  1 
ATOM   6658 N NE  . ARG A 1 1005 ? 105.921 120.778 132.589 1.00 36.86  ? 964  ARG A NE  1 
ATOM   6659 C CZ  . ARG A 1 1005 ? 105.859 121.820 133.405 1.00 36.86  ? 964  ARG A CZ  1 
ATOM   6660 N NH1 . ARG A 1 1005 ? 105.779 123.054 132.941 1.00 36.86  ? 964  ARG A NH1 1 
ATOM   6661 N NH2 . ARG A 1 1005 ? 105.878 121.619 134.718 1.00 36.86  ? 964  ARG A NH2 1 
ATOM   6662 N N   . VAL A 1 1006 ? 109.749 116.844 130.479 1.00 39.82  ? 965  VAL A N   1 
ATOM   6663 C CA  . VAL A 1 1006 ? 111.147 116.573 130.148 1.00 39.82  ? 965  VAL A CA  1 
ATOM   6664 C C   . VAL A 1 1006 ? 111.241 115.496 129.076 1.00 39.82  ? 965  VAL A C   1 
ATOM   6665 O O   . VAL A 1 1006 ? 111.923 115.665 128.054 1.00 39.82  ? 965  VAL A O   1 
ATOM   6666 C CB  . VAL A 1 1006 ? 111.929 116.165 131.408 1.00 39.82  ? 965  VAL A CB  1 
ATOM   6667 C CG1 . VAL A 1 1006 ? 113.270 115.588 131.022 1.00 39.82  ? 965  VAL A CG1 1 
ATOM   6668 C CG2 . VAL A 1 1006 ? 112.116 117.344 132.312 1.00 39.82  ? 965  VAL A CG2 1 
ATOM   6669 N N   . PHE A 1 1007 ? 110.551 114.374 129.291 1.00 38.62  ? 966  PHE A N   1 
ATOM   6670 C CA  . PHE A 1 1007 ? 110.621 113.271 128.340 1.00 38.62  ? 966  PHE A CA  1 
ATOM   6671 C C   . PHE A 1 1007 ? 110.171 113.712 126.956 1.00 38.62  ? 966  PHE A C   1 
ATOM   6672 O O   . PHE A 1 1007 ? 110.882 113.509 125.963 1.00 38.62  ? 966  PHE A O   1 
ATOM   6673 C CB  . PHE A 1 1007 ? 109.769 112.101 128.825 1.00 38.62  ? 966  PHE A CB  1 
ATOM   6674 C CG  . PHE A 1 1007 ? 109.734 110.946 127.869 1.00 38.62  ? 966  PHE A CG  1 
ATOM   6675 C CD1 . PHE A 1 1007 ? 110.819 110.101 127.741 1.00 38.62  ? 966  PHE A CD1 1 
ATOM   6676 C CD2 . PHE A 1 1007 ? 108.619 110.716 127.083 1.00 38.62  ? 966  PHE A CD2 1 
ATOM   6677 C CE1 . PHE A 1 1007 ? 110.787 109.044 126.858 1.00 38.62  ? 966  PHE A CE1 1 
ATOM   6678 C CE2 . PHE A 1 1007 ? 108.586 109.661 126.198 1.00 38.62  ? 966  PHE A CE2 1 
ATOM   6679 C CZ  . PHE A 1 1007 ? 109.670 108.825 126.087 1.00 38.62  ? 966  PHE A CZ  1 
ATOM   6680 N N   . MET A 1 1008 ? 108.990 114.323 126.871 1.00 37.66  ? 967  MET A N   1 
ATOM   6681 C CA  . MET A 1 1008 ? 108.438 114.679 125.574 1.00 37.66  ? 967  MET A CA  1 
ATOM   6682 C C   . MET A 1 1008 ? 109.306 115.715 124.871 1.00 37.66  ? 967  MET A C   1 
ATOM   6683 O O   . MET A 1 1008 ? 109.564 115.607 123.667 1.00 37.66  ? 967  MET A O   1 
ATOM   6684 C CB  . MET A 1 1008 ? 107.006 115.181 125.741 1.00 37.66  ? 967  MET A CB  1 
ATOM   6685 C CG  . MET A 1 1008 ? 105.959 114.093 125.672 1.00 37.66  ? 967  MET A CG  1 
ATOM   6686 S SD  . MET A 1 1008 ? 105.453 113.763 123.981 1.00 37.66  ? 967  MET A SD  1 
ATOM   6687 C CE  . MET A 1 1008 ? 104.054 114.865 123.829 1.00 37.66  ? 967  MET A CE  1 
ATOM   6688 N N   . VAL A 1 1009 ? 109.782 116.727 125.605 1.00 39.95  ? 968  VAL A N   1 
ATOM   6689 C CA  . VAL A 1 1009 ? 110.565 117.772 124.958 1.00 39.95  ? 968  VAL A CA  1 
ATOM   6690 C C   . VAL A 1 1009 ? 111.868 117.197 124.419 1.00 39.95  ? 968  VAL A C   1 
ATOM   6691 O O   . VAL A 1 1009 ? 112.248 117.466 123.274 1.00 39.95  ? 968  VAL A O   1 
ATOM   6692 C CB  . VAL A 1 1009 ? 110.800 118.965 125.908 1.00 39.95  ? 968  VAL A CB  1 
ATOM   6693 C CG1 . VAL A 1 1009 ? 111.775 118.640 127.020 1.00 39.95  ? 968  VAL A CG1 1 
ATOM   6694 C CG2 . VAL A 1 1009 ? 111.293 120.166 125.128 1.00 39.95  ? 968  VAL A CG2 1 
ATOM   6695 N N   . LEU A 1 1010 ? 112.543 116.351 125.203 1.00 39.80  ? 969  LEU A N   1 
ATOM   6696 C CA  . LEU A 1 1010 ? 113.808 115.801 124.728 1.00 39.80  ? 969  LEU A CA  1 
ATOM   6697 C C   . LEU A 1 1010 ? 113.601 114.861 123.548 1.00 39.80  ? 969  LEU A C   1 
ATOM   6698 O O   . LEU A 1 1010 ? 114.388 114.870 122.596 1.00 39.80  ? 969  LEU A O   1 
ATOM   6699 C CB  . LEU A 1 1010 ? 114.558 115.109 125.864 1.00 39.80  ? 969  LEU A CB  1 
ATOM   6700 C CG  . LEU A 1 1010 ? 115.010 116.092 126.943 1.00 39.80  ? 969  LEU A CG  1 
ATOM   6701 C CD1 . LEU A 1 1010 ? 115.628 115.380 128.123 1.00 39.80  ? 969  LEU A CD1 1 
ATOM   6702 C CD2 . LEU A 1 1010 ? 115.994 117.073 126.348 1.00 39.80  ? 969  LEU A CD2 1 
ATOM   6703 N N   . MET A 1 1011 ? 112.534 114.061 123.565 1.00 39.73  ? 970  MET A N   1 
ATOM   6704 C CA  . MET A 1 1011 ? 112.361 113.097 122.483 1.00 39.73  ? 970  MET A CA  1 
ATOM   6705 C C   . MET A 1 1011 ? 111.945 113.781 121.184 1.00 39.73  ? 970  MET A C   1 
ATOM   6706 O O   . MET A 1 1011 ? 112.466 113.465 120.104 1.00 39.73  ? 970  MET A O   1 
ATOM   6707 C CB  . MET A 1 1011 ? 111.357 112.024 122.892 1.00 39.73  ? 970  MET A CB  1 
ATOM   6708 C CG  . MET A 1 1011 ? 111.900 111.134 123.986 1.00 39.73  ? 970  MET A CG  1 
ATOM   6709 S SD  . MET A 1 1011 ? 113.674 110.897 123.789 1.00 39.73  ? 970  MET A SD  1 
ATOM   6710 C CE  . MET A 1 1011 ? 113.951 109.459 124.809 1.00 39.73  ? 970  MET A CE  1 
ATOM   6711 N N   . VAL A 1 1012 ? 111.017 114.738 121.262 1.00 44.04  ? 971  VAL A N   1 
ATOM   6712 C CA  . VAL A 1 1012 ? 110.628 115.455 120.054 1.00 44.04  ? 971  VAL A CA  1 
ATOM   6713 C C   . VAL A 1 1012 ? 111.784 116.306 119.539 1.00 44.04  ? 971  VAL A C   1 
ATOM   6714 O O   . VAL A 1 1012 ? 111.963 116.464 118.326 1.00 44.04  ? 971  VAL A O   1 
ATOM   6715 C CB  . VAL A 1 1012 ? 109.360 116.290 120.306 1.00 44.04  ? 971  VAL A CB  1 
ATOM   6716 C CG1 . VAL A 1 1012 ? 108.948 117.023 119.045 1.00 44.04  ? 971  VAL A CG1 1 
ATOM   6717 C CG2 . VAL A 1 1012 ? 108.235 115.396 120.776 1.00 44.04  ? 971  VAL A CG2 1 
ATOM   6718 N N   . SER A 1 1013 ? 112.603 116.855 120.441 1.00 43.05  ? 972  SER A N   1 
ATOM   6719 C CA  . SER A 1 1013 ? 113.776 117.599 119.999 1.00 43.05  ? 972  SER A CA  1 
ATOM   6720 C C   . SER A 1 1013 ? 114.801 116.683 119.343 1.00 43.05  ? 972  SER A C   1 
ATOM   6721 O O   . SER A 1 1013 ? 115.495 117.092 118.408 1.00 43.05  ? 972  SER A O   1 
ATOM   6722 C CB  . SER A 1 1013 ? 114.394 118.345 121.177 1.00 43.05  ? 972  SER A CB  1 
ATOM   6723 O OG  . SER A 1 1013 ? 113.466 119.258 121.732 1.00 43.05  ? 972  SER A OG  1 
ATOM   6724 N N   . ALA A 1 1014 ? 114.923 115.446 119.823 1.00 45.81  ? 973  ALA A N   1 
ATOM   6725 C CA  . ALA A 1 1014 ? 115.790 114.484 119.151 1.00 45.81  ? 973  ALA A CA  1 
ATOM   6726 C C   . ALA A 1 1014 ? 115.293 114.197 117.743 1.00 45.81  ? 973  ALA A C   1 
ATOM   6727 O O   . ALA A 1 1014 ? 116.085 114.117 116.795 1.00 45.81  ? 973  ALA A O   1 
ATOM   6728 C CB  . ALA A 1 1014 ? 115.871 113.192 119.960 1.00 45.81  ? 973  ALA A CB  1 
ATOM   6729 N N   . ASN A 1 1015 ? 113.978 114.042 117.591 1.00 49.34  ? 974  ASN A N   1 
ATOM   6730 C CA  . ASN A 1 1015 ? 113.412 113.854 116.260 1.00 49.34  ? 974  ASN A CA  1 
ATOM   6731 C C   . ASN A 1 1015 ? 113.708 115.052 115.366 1.00 49.34  ? 974  ASN A C   1 
ATOM   6732 O O   . ASN A 1 1015 ? 114.066 114.896 114.193 1.00 49.34  ? 974  ASN A O   1 
ATOM   6733 C CB  . ASN A 1 1015 ? 111.908 113.609 116.364 1.00 49.34  ? 974  ASN A CB  1 
ATOM   6734 C CG  . ASN A 1 1015 ? 111.260 113.373 115.020 1.00 49.34  ? 974  ASN A CG  1 
ATOM   6735 O OD1 . ASN A 1 1015 ? 111.084 114.299 114.229 1.00 49.34  ? 974  ASN A OD1 1 
ATOM   6736 N ND2 . ASN A 1 1015 ? 110.911 112.125 114.747 1.00 49.34  ? 974  ASN A ND2 1 
ATOM   6737 N N   . GLY A 1 1016 ? 113.564 116.261 115.908 1.00 49.43  ? 975  GLY A N   1 
ATOM   6738 C CA  . GLY A 1 1016 ? 113.857 117.453 115.126 1.00 49.43  ? 975  GLY A CA  1 
ATOM   6739 C C   . GLY A 1 1016 ? 115.316 117.551 114.721 1.00 49.43  ? 975  GLY A C   1 
ATOM   6740 O O   . GLY A 1 1016 ? 115.634 117.941 113.596 1.00 49.43  ? 975  GLY A O   1 
ATOM   6741 N N   . ALA A 1 1017 ? 116.222 117.202 115.633 1.00 50.74  ? 976  ALA A N   1 
ATOM   6742 C CA  . ALA A 1 1017 ? 117.643 117.212 115.305 1.00 50.74  ? 976  ALA A CA  1 
ATOM   6743 C C   . ALA A 1 1017 ? 117.955 116.214 114.202 1.00 50.74  ? 976  ALA A C   1 
ATOM   6744 O O   . ALA A 1 1017 ? 118.697 116.525 113.261 1.00 50.74  ? 976  ALA A O   1 
ATOM   6745 C CB  . ALA A 1 1017 ? 118.472 116.908 116.552 1.00 50.74  ? 976  ALA A CB  1 
ATOM   6746 N N   . ALA A 1 1018 ? 117.387 115.011 114.290 1.00 55.62  ? 977  ALA A N   1 
ATOM   6747 C CA  . ALA A 1 1018 ? 117.605 114.025 113.239 1.00 55.62  ? 977  ALA A CA  1 
ATOM   6748 C C   . ALA A 1 1018 ? 117.052 114.511 111.908 1.00 55.62  ? 977  ALA A C   1 
ATOM   6749 O O   . ALA A 1 1018 ? 117.661 114.292 110.856 1.00 55.62  ? 977  ALA A O   1 
ATOM   6750 C CB  . ALA A 1 1018 ? 116.975 112.695 113.630 1.00 55.62  ? 977  ALA A CB  1 
ATOM   6751 N N   . GLU A 1 1019 ? 115.891 115.169 111.932 1.00 61.12  ? 978  GLU A N   1 
ATOM   6752 C CA  . GLU A 1 1019 ? 115.342 115.741 110.708 1.00 61.12  ? 978  GLU A CA  1 
ATOM   6753 C C   . GLU A 1 1019 ? 116.259 116.821 110.148 1.00 61.12  ? 978  GLU A C   1 
ATOM   6754 O O   . GLU A 1 1019 ? 116.342 117.008 108.930 1.00 61.12  ? 978  GLU A O   1 
ATOM   6755 C CB  . GLU A 1 1019 ? 113.946 116.298 110.977 1.00 61.12  ? 978  GLU A CB  1 
ATOM   6756 C CG  . GLU A 1 1019 ? 113.233 116.838 109.755 1.00 61.12  ? 978  GLU A CG  1 
ATOM   6757 C CD  . GLU A 1 1019 ? 111.827 117.308 110.073 1.00 61.12  ? 978  GLU A CD  1 
ATOM   6758 O OE1 . GLU A 1 1019 ? 111.425 117.229 111.253 1.00 61.12  ? 978  GLU A OE1 1 
ATOM   6759 O OE2 . GLU A 1 1019 ? 111.120 117.751 109.145 1.00 61.12  ? 978  GLU A OE2 1 
ATOM   6760 N N   . THR A 1 1020 ? 116.944 117.552 111.028 1.00 58.50  ? 979  THR A N   1 
ATOM   6761 C CA  . THR A 1 1020 ? 117.929 118.528 110.570 1.00 58.50  ? 979  THR A CA  1 
ATOM   6762 C C   . THR A 1 1020 ? 119.117 117.844 109.903 1.00 58.50  ? 979  THR A C   1 
ATOM   6763 O O   . THR A 1 1020 ? 119.632 118.336 108.893 1.00 58.50  ? 979  THR A O   1 
ATOM   6764 C CB  . THR A 1 1020 ? 118.395 119.400 111.734 1.00 58.50  ? 979  THR A CB  1 
ATOM   6765 O OG1 . THR A 1 1020 ? 117.283 120.133 112.259 1.00 58.50  ? 979  THR A OG1 1 
ATOM   6766 C CG2 . THR A 1 1020 ? 119.456 120.379 111.276 1.00 58.50  ? 979  THR A CG2 1 
ATOM   6767 N N   . LEU A 1 1021 ? 119.559 116.704 110.443 1.00 60.18  ? 980  LEU A N   1 
ATOM   6768 C CA  . LEU A 1 1021 ? 120.677 115.986 109.830 1.00 60.18  ? 980  LEU A CA  1 
ATOM   6769 C C   . LEU A 1 1021 ? 120.362 115.494 108.423 1.00 60.18  ? 980  LEU A C   1 
ATOM   6770 O O   . LEU A 1 1021 ? 121.286 115.126 107.690 1.00 60.18  ? 980  LEU A O   1 
ATOM   6771 C CB  . LEU A 1 1021 ? 121.105 114.790 110.683 1.00 60.18  ? 980  LEU A CB  1 
ATOM   6772 C CG  . LEU A 1 1021 ? 122.159 114.946 111.783 1.00 60.18  ? 980  LEU A CG  1 
ATOM   6773 C CD1 . LEU A 1 1021 ? 123.489 115.373 111.188 1.00 60.18  ? 980  LEU A CD1 1 
ATOM   6774 C CD2 . LEU A 1 1021 ? 121.730 115.900 112.861 1.00 60.18  ? 980  LEU A CD2 1 
ATOM   6775 N N   . THR A 1 1022 ? 119.086 115.463 108.032 1.00 70.25  ? 981  THR A N   1 
ATOM   6776 C CA  . THR A 1 1022 ? 118.726 115.051 106.679 1.00 70.25  ? 981  THR A CA  1 
ATOM   6777 C C   . THR A 1 1022 ? 119.306 115.978 105.616 1.00 70.25  ? 981  THR A C   1 
ATOM   6778 O O   . THR A 1 1022 ? 119.452 115.557 104.462 1.00 70.25  ? 981  THR A O   1 
ATOM   6779 C CB  . THR A 1 1022 ? 117.200 114.971 106.559 1.00 70.25  ? 981  THR A CB  1 
ATOM   6780 O OG1 . THR A 1 1022 ? 116.690 114.120 107.592 1.00 70.25  ? 981  THR A OG1 1 
ATOM   6781 C CG2 . THR A 1 1022 ? 116.777 114.400 105.215 1.00 70.25  ? 981  THR A CG2 1 
ATOM   6782 N N   . LEU A 1 1023 ? 119.663 117.210 105.975 1.00 83.67  ? 982  LEU A N   1 
ATOM   6783 C CA  . LEU A 1 1023 ? 120.357 118.092 105.046 1.00 83.67  ? 982  LEU A CA  1 
ATOM   6784 C C   . LEU A 1 1023 ? 121.686 117.468 104.637 1.00 83.67  ? 982  LEU A C   1 
ATOM   6785 O O   . LEU A 1 1023 ? 122.307 116.741 105.414 1.00 83.67  ? 982  LEU A O   1 
ATOM   6786 C CB  . LEU A 1 1023 ? 120.584 119.460 105.687 1.00 83.67  ? 982  LEU A CB  1 
ATOM   6787 C CG  . LEU A 1 1023 ? 119.307 120.193 106.110 1.00 83.67  ? 982  LEU A CG  1 
ATOM   6788 C CD1 . LEU A 1 1023 ? 119.636 121.518 106.787 1.00 83.67  ? 982  LEU A CD1 1 
ATOM   6789 C CD2 . LEU A 1 1023 ? 118.372 120.398 104.925 1.00 83.67  ? 982  LEU A CD2 1 
ATOM   6790 N N   . ALA A 1 1024 ? 122.122 117.773 103.408 1.00 108.52 ? 983  ALA A N   1 
ATOM   6791 C CA  . ALA A 1 1024 ? 123.153 117.021 102.693 1.00 108.52 ? 983  ALA A CA  1 
ATOM   6792 C C   . ALA A 1 1024 ? 124.382 116.732 103.547 1.00 108.52 ? 983  ALA A C   1 
ATOM   6793 O O   . ALA A 1 1024 ? 125.166 117.642 103.847 1.00 108.52 ? 983  ALA A O   1 
ATOM   6794 C CB  . ALA A 1 1024 ? 123.571 117.778 101.431 1.00 108.52 ? 983  ALA A CB  1 
ATOM   6795 N N   . PRO A 1 1025 ? 124.582 115.472 103.951 1.00 118.98 ? 984  PRO A N   1 
ATOM   6796 C CA  . PRO A 1 1025 ? 125.771 115.115 104.734 1.00 118.98 ? 984  PRO A CA  1 
ATOM   6797 C C   . PRO A 1 1025 ? 126.941 114.666 103.872 1.00 118.98 ? 984  PRO A C   1 
ATOM   6798 O O   . PRO A 1 1025 ? 127.471 113.568 104.067 1.00 118.98 ? 984  PRO A O   1 
ATOM   6799 C CB  . PRO A 1 1025 ? 125.260 113.975 105.620 1.00 118.98 ? 984  PRO A CB  1 
ATOM   6800 C CG  . PRO A 1 1025 ? 124.250 113.287 104.748 1.00 118.98 ? 984  PRO A CG  1 
ATOM   6801 C CD  . PRO A 1 1025 ? 123.636 114.346 103.851 1.00 118.98 ? 984  PRO A CD  1 
ATOM   6802 N N   . ASP A 1 1026 ? 127.356 115.496 102.921 1.00 127.36 ? 985  ASP A N   1 
ATOM   6803 C CA  . ASP A 1 1026 ? 128.459 115.166 102.030 1.00 127.36 ? 985  ASP A CA  1 
ATOM   6804 C C   . ASP A 1 1026 ? 129.810 115.605 102.582 1.00 127.36 ? 985  ASP A C   1 
ATOM   6805 O O   . ASP A 1 1026 ? 130.731 115.868 101.801 1.00 127.36 ? 985  ASP A O   1 
ATOM   6806 C CB  . ASP A 1 1026 ? 128.223 115.792 100.654 1.00 127.36 ? 985  ASP A CB  1 
ATOM   6807 C CG  . ASP A 1 1026 ? 127.098 115.115 99.892  1.00 127.36 ? 985  ASP A CG  1 
ATOM   6808 O OD1 . ASP A 1 1026 ? 126.881 113.904 100.104 1.00 127.36 ? 985  ASP A OD1 1 
ATOM   6809 O OD2 . ASP A 1 1026 ? 126.431 115.794 99.083  1.00 127.36 ? 985  ASP A OD2 1 
ATOM   6810 N N   . PHE A 1 1027 ? 129.945 115.681 103.907 1.00 121.08 ? 986  PHE A N   1 
ATOM   6811 C CA  . PHE A 1 1027 ? 131.092 116.312 104.547 1.00 121.08 ? 986  PHE A CA  1 
ATOM   6812 C C   . PHE A 1 1027 ? 132.419 115.626 104.223 1.00 121.08 ? 986  PHE A C   1 
ATOM   6813 O O   . PHE A 1 1027 ? 133.437 116.292 104.007 1.00 121.08 ? 986  PHE A O   1 
ATOM   6814 C CB  . PHE A 1 1027 ? 130.857 116.351 106.060 1.00 121.08 ? 986  PHE A CB  1 
ATOM   6815 C CG  . PHE A 1 1027 ? 129.486 116.833 106.449 1.00 121.08 ? 986  PHE A CG  1 
ATOM   6816 C CD1 . PHE A 1 1027 ? 128.891 117.892 105.779 1.00 121.08 ? 986  PHE A CD1 1 
ATOM   6817 C CD2 . PHE A 1 1027 ? 128.798 116.237 107.493 1.00 121.08 ? 986  PHE A CD2 1 
ATOM   6818 C CE1 . PHE A 1 1027 ? 127.631 118.338 106.136 1.00 121.08 ? 986  PHE A CE1 1 
ATOM   6819 C CE2 . PHE A 1 1027 ? 127.538 116.679 107.855 1.00 121.08 ? 986  PHE A CE2 1 
ATOM   6820 C CZ  . PHE A 1 1027 ? 126.954 117.731 107.177 1.00 121.08 ? 986  PHE A CZ  1 
ATOM   6821 N N   . ILE A 1 1028 ? 132.437 114.292 104.204 1.00 134.54 ? 987  ILE A N   1 
ATOM   6822 C CA  . ILE A 1 1028 ? 133.676 113.577 103.897 1.00 134.54 ? 987  ILE A CA  1 
ATOM   6823 C C   . ILE A 1 1028 ? 134.066 113.790 102.438 1.00 134.54 ? 987  ILE A C   1 
ATOM   6824 O O   . ILE A 1 1028 ? 135.231 114.069 102.115 1.00 134.54 ? 987  ILE A O   1 
ATOM   6825 C CB  . ILE A 1 1028 ? 133.529 112.082 104.231 1.00 134.54 ? 987  ILE A CB  1 
ATOM   6826 C CG1 . ILE A 1 1028 ? 132.974 111.906 105.646 1.00 134.54 ? 987  ILE A CG1 1 
ATOM   6827 C CG2 . ILE A 1 1028 ? 134.865 111.370 104.083 1.00 134.54 ? 987  ILE A CG2 1 
ATOM   6828 C CD1 . ILE A 1 1028 ? 132.770 110.464 106.048 1.00 134.54 ? 987  ILE A CD1 1 
ATOM   6829 N N   . LYS A 1 1029 ? 133.094 113.653 101.534 1.00 132.02 ? 988  LYS A N   1 
ATOM   6830 C CA  . LYS A 1 1029 ? 133.339 113.968 100.131 1.00 132.02 ? 988  LYS A CA  1 
ATOM   6831 C C   . LYS A 1 1029 ? 133.741 115.428 99.979  1.00 132.02 ? 988  LYS A C   1 
ATOM   6832 O O   . LYS A 1 1029 ? 134.589 115.772 99.146  1.00 132.02 ? 988  LYS A O   1 
ATOM   6833 C CB  . LYS A 1 1029 ? 132.094 113.664 99.297  1.00 132.02 ? 988  LYS A CB  1 
ATOM   6834 C CG  . LYS A 1 1029 ? 131.320 112.427 99.732  1.00 132.02 ? 988  LYS A CG  1 
ATOM   6835 C CD  . LYS A 1 1029 ? 132.172 111.168 99.682  1.00 132.02 ? 988  LYS A CD  1 
ATOM   6836 C CE  . LYS A 1 1029 ? 131.417 109.980 100.256 1.00 132.02 ? 988  LYS A CE  1 
ATOM   6837 N NZ  . LYS A 1 1029 ? 132.239 108.738 100.259 1.00 132.02 ? 988  LYS A NZ  1 
ATOM   6838 N N   . GLY A 1 1030 ? 133.133 116.301 100.785 1.00 127.33 ? 989  GLY A N   1 
ATOM   6839 C CA  . GLY A 1 1030 ? 133.513 117.700 100.767 1.00 127.33 ? 989  GLY A CA  1 
ATOM   6840 C C   . GLY A 1 1030 ? 134.966 117.911 101.139 1.00 127.33 ? 989  GLY A C   1 
ATOM   6841 O O   . GLY A 1 1030 ? 135.661 118.711 100.517 1.00 127.33 ? 989  GLY A O   1 
ATOM   6842 N N   . GLY A 1 1031 ? 135.450 117.185 102.148 1.00 130.24 ? 990  GLY A N   1 
ATOM   6843 C CA  . GLY A 1 1031 ? 136.851 117.298 102.522 1.00 130.24 ? 990  GLY A CA  1 
ATOM   6844 C C   . GLY A 1 1031 ? 137.787 116.761 101.455 1.00 130.24 ? 990  GLY A C   1 
ATOM   6845 O O   . GLY A 1 1031 ? 138.850 117.339 101.192 1.00 130.24 ? 990  GLY A O   1 
ATOM   6846 N N   . GLN A 1 1032 ? 137.411 115.645 100.829 1.00 126.78 ? 991  GLN A N   1 
ATOM   6847 C CA  . GLN A 1 1032 ? 138.241 115.098 99.759  1.00 126.78 ? 991  GLN A CA  1 
ATOM   6848 C C   . GLN A 1 1032 ? 138.341 116.075 98.590  1.00 126.78 ? 991  GLN A C   1 
ATOM   6849 O O   . GLN A 1 1032 ? 139.434 116.333 98.066  1.00 126.78 ? 991  GLN A O   1 
ATOM   6850 C CB  . GLN A 1 1032 ? 137.687 113.750 99.299  1.00 126.78 ? 991  GLN A CB  1 
ATOM   6851 C CG  . GLN A 1 1032 ? 138.712 112.840 98.626  1.00 126.78 ? 991  GLN A CG  1 
ATOM   6852 C CD  . GLN A 1 1032 ? 139.782 112.318 99.575  1.00 126.78 ? 991  GLN A CD  1 
ATOM   6853 O OE1 . GLN A 1 1032 ? 139.845 112.704 100.743 1.00 126.78 ? 991  GLN A OE1 1 
ATOM   6854 N NE2 . GLN A 1 1032 ? 140.632 111.433 99.069  1.00 126.78 ? 991  GLN A NE2 1 
ATOM   6855 N N   . ALA A 1 1033 ? 137.208 116.649 98.182  1.00 119.35 ? 992  ALA A N   1 
ATOM   6856 C CA  . ALA A 1 1033 ? 137.237 117.644 97.118  1.00 119.35 ? 992  ALA A CA  1 
ATOM   6857 C C   . ALA A 1 1033 ? 137.946 118.914 97.559  1.00 119.35 ? 992  ALA A C   1 
ATOM   6858 O O   . ALA A 1 1033 ? 138.537 119.613 96.730  1.00 119.35 ? 992  ALA A O   1 
ATOM   6859 C CB  . ALA A 1 1033 ? 135.823 117.966 96.658  1.00 119.35 ? 992  ALA A CB  1 
ATOM   6860 N N   . MET A 1 1034 ? 137.885 119.234 98.849  1.00 119.24 ? 993  MET A N   1 
ATOM   6861 C CA  . MET A 1 1034 ? 138.640 120.357 99.384  1.00 119.24 ? 993  MET A CA  1 
ATOM   6862 C C   . MET A 1 1034 ? 140.129 120.158 99.141  1.00 119.24 ? 993  MET A C   1 
ATOM   6863 O O   . MET A 1 1034 ? 140.813 121.050 98.622  1.00 119.24 ? 993  MET A O   1 
ATOM   6864 C CB  . MET A 1 1034 ? 138.344 120.476 100.877 1.00 119.24 ? 993  MET A CB  1 
ATOM   6865 C CG  . MET A 1 1034 ? 138.936 121.662 101.592 1.00 119.24 ? 993  MET A CG  1 
ATOM   6866 S SD  . MET A 1 1034 ? 138.463 121.605 103.335 1.00 119.24 ? 993  MET A SD  1 
ATOM   6867 C CE  . MET A 1 1034 ? 136.722 122.013 103.259 1.00 119.24 ? 993  MET A CE  1 
ATOM   6868 N N   . ARG A 1 1035 ? 140.636 118.970 99.474  1.00 123.11 ? 994  ARG A N   1 
ATOM   6869 C CA  . ARG A 1 1035 ? 142.039 118.668 99.205  1.00 123.11 ? 994  ARG A CA  1 
ATOM   6870 C C   . ARG A 1 1035 ? 142.336 118.702 97.711  1.00 123.11 ? 994  ARG A C   1 
ATOM   6871 O O   . ARG A 1 1035 ? 143.393 119.189 97.293  1.00 123.11 ? 994  ARG A O   1 
ATOM   6872 C CB  . ARG A 1 1035 ? 142.417 117.309 99.789  1.00 123.11 ? 994  ARG A CB  1 
ATOM   6873 C CG  . ARG A 1 1035 ? 143.893 116.974 99.618  1.00 123.11 ? 994  ARG A CG  1 
ATOM   6874 C CD  . ARG A 1 1035 ? 144.343 115.880 100.570 1.00 123.11 ? 994  ARG A CD  1 
ATOM   6875 N NE  . ARG A 1 1035 ? 143.580 115.881 101.811 1.00 123.11 ? 994  ARG A NE  1 
ATOM   6876 C CZ  . ARG A 1 1035 ? 142.852 114.860 102.240 1.00 123.11 ? 994  ARG A CZ  1 
ATOM   6877 N NH1 . ARG A 1 1035 ? 142.744 113.746 101.534 1.00 123.11 ? 994  ARG A NH1 1 
ATOM   6878 N NH2 . ARG A 1 1035 ? 142.215 114.959 103.402 1.00 123.11 ? 994  ARG A NH2 1 
ATOM   6879 N N   . SER A 1 1036 ? 141.423 118.177 96.890  1.00 111.52 ? 995  SER A N   1 
ATOM   6880 C CA  . SER A 1 1036 ? 141.646 118.167 95.446  1.00 111.52 ? 995  SER A CA  1 
ATOM   6881 C C   . SER A 1 1036 ? 141.790 119.584 94.893  1.00 111.52 ? 995  SER A C   1 
ATOM   6882 O O   . SER A 1 1036 ? 142.747 119.892 94.171  1.00 111.52 ? 995  SER A O   1 
ATOM   6883 C CB  . SER A 1 1036 ? 140.507 117.430 94.742  1.00 111.52 ? 995  SER A CB  1 
ATOM   6884 O OG  . SER A 1 1036 ? 140.324 116.136 95.285  1.00 111.52 ? 995  SER A OG  1 
ATOM   6885 N N   . VAL A 1 1037 ? 140.846 120.466 95.229  1.00 102.87 ? 996  VAL A N   1 
ATOM   6886 C CA  . VAL A 1 1037 ? 140.912 121.832 94.719  1.00 102.87 ? 996  VAL A CA  1 
ATOM   6887 C C   . VAL A 1 1037 ? 142.133 122.548 95.274  1.00 102.87 ? 996  VAL A C   1 
ATOM   6888 O O   . VAL A 1 1037 ? 142.746 123.374 94.590  1.00 102.87 ? 996  VAL A O   1 
ATOM   6889 C CB  . VAL A 1 1037 ? 139.611 122.603 95.024  1.00 102.87 ? 996  VAL A CB  1 
ATOM   6890 C CG1 . VAL A 1 1037 ? 138.427 121.853 94.489  1.00 102.87 ? 996  VAL A CG1 1 
ATOM   6891 C CG2 . VAL A 1 1037 ? 139.448 122.863 96.505  1.00 102.87 ? 996  VAL A CG2 1 
ATOM   6892 N N   . PHE A 1 1038 ? 142.523 122.238 96.510  1.00 106.94 ? 997  PHE A N   1 
ATOM   6893 C CA  . PHE A 1 1038 ? 143.653 122.943 97.099  1.00 106.94 ? 997  PHE A CA  1 
ATOM   6894 C C   . PHE A 1 1038 ? 144.962 122.530 96.443  1.00 106.94 ? 997  PHE A C   1 
ATOM   6895 O O   . PHE A 1 1038 ? 145.831 123.370 96.179  1.00 106.94 ? 997  PHE A O   1 
ATOM   6896 C CB  . PHE A 1 1038 ? 143.679 122.700 98.602  1.00 106.94 ? 997  PHE A CB  1 
ATOM   6897 C CG  . PHE A 1 1038 ? 142.991 123.770 99.380  1.00 106.94 ? 997  PHE A CG  1 
ATOM   6898 C CD1 . PHE A 1 1038 ? 141.624 123.942 99.267  1.00 106.94 ? 997  PHE A CD1 1 
ATOM   6899 C CD2 . PHE A 1 1038 ? 143.705 124.635 100.180 1.00 106.94 ? 997  PHE A CD2 1 
ATOM   6900 C CE1 . PHE A 1 1038 ? 140.981 124.931 99.962  1.00 106.94 ? 997  PHE A CE1 1 
ATOM   6901 C CE2 . PHE A 1 1038 ? 143.061 125.621 100.882 1.00 106.94 ? 997  PHE A CE2 1 
ATOM   6902 C CZ  . PHE A 1 1038 ? 141.698 125.775 100.770 1.00 106.94 ? 997  PHE A CZ  1 
ATOM   6903 N N   . GLU A 1 1039 ? 145.118 121.237 96.150  1.00 107.17 ? 998  GLU A N   1 
ATOM   6904 C CA  . GLU A 1 1039 ? 146.326 120.801 95.458  1.00 107.17 ? 998  GLU A CA  1 
ATOM   6905 C C   . GLU A 1 1039 ? 146.341 121.300 94.018  1.00 107.17 ? 998  GLU A C   1 
ATOM   6906 O O   . GLU A 1 1039 ? 147.411 121.573 93.463  1.00 107.17 ? 998  GLU A O   1 
ATOM   6907 C CB  . GLU A 1 1039 ? 146.464 119.278 95.519  1.00 107.17 ? 998  GLU A CB  1 
ATOM   6908 C CG  . GLU A 1 1039 ? 145.357 118.491 94.850  1.00 107.17 ? 998  GLU A CG  1 
ATOM   6909 C CD  . GLU A 1 1039 ? 145.648 118.189 93.397  1.00 107.17 ? 998  GLU A CD  1 
ATOM   6910 O OE1 . GLU A 1 1039 ? 146.753 118.531 92.927  1.00 107.17 ? 998  GLU A OE1 1 
ATOM   6911 O OE2 . GLU A 1 1039 ? 144.772 117.604 92.725  1.00 107.17 ? 998  GLU A OE2 1 
ATOM   6912 N N   . LEU A 1 1040 ? 145.166 121.426 93.394  1.00 98.06  ? 999  LEU A N   1 
ATOM   6913 C CA  . LEU A 1 1040 ? 145.113 122.027 92.064  1.00 98.06  ? 999  LEU A CA  1 
ATOM   6914 C C   . LEU A 1 1040 ? 145.531 123.494 92.100  1.00 98.06  ? 999  LEU A C   1 
ATOM   6915 O O   . LEU A 1 1040 ? 146.272 123.955 91.224  1.00 98.06  ? 999  LEU A O   1 
ATOM   6916 C CB  . LEU A 1 1040 ? 143.712 121.885 91.476  1.00 98.06  ? 999  LEU A CB  1 
ATOM   6917 C CG  . LEU A 1 1040 ? 143.456 122.650 90.179  1.00 98.06  ? 999  LEU A CG  1 
ATOM   6918 C CD1 . LEU A 1 1040 ? 144.392 122.171 89.089  1.00 98.06  ? 999  LEU A CD1 1 
ATOM   6919 C CD2 . LEU A 1 1040 ? 142.010 122.494 89.750  1.00 98.06  ? 999  LEU A CD2 1 
ATOM   6920 N N   . LEU A 1 1041 ? 145.061 124.243 93.099  1.00 97.24  ? 1000 LEU A N   1 
ATOM   6921 C CA  . LEU A 1 1041 ? 145.414 125.657 93.200  1.00 97.24  ? 1000 LEU A CA  1 
ATOM   6922 C C   . LEU A 1 1041 ? 146.894 125.845 93.507  1.00 97.24  ? 1000 LEU A C   1 
ATOM   6923 O O   . LEU A 1 1041 ? 147.538 126.746 92.959  1.00 97.24  ? 1000 LEU A O   1 
ATOM   6924 C CB  . LEU A 1 1041 ? 144.565 126.337 94.272  1.00 97.24  ? 1000 LEU A CB  1 
ATOM   6925 C CG  . LEU A 1 1041 ? 143.342 127.124 93.810  1.00 97.24  ? 1000 LEU A CG  1 
ATOM   6926 C CD1 . LEU A 1 1041 ? 142.299 126.197 93.241  1.00 97.24  ? 1000 LEU A CD1 1 
ATOM   6927 C CD2 . LEU A 1 1041 ? 142.767 127.929 94.961  1.00 97.24  ? 1000 LEU A CD2 1 
ATOM   6928 N N   . ASP A 1 1042 ? 147.450 125.015 94.384  1.00 106.73 ? 1001 ASP A N   1 
ATOM   6929 C CA  . ASP A 1 1042 ? 148.816 125.208 94.850  1.00 106.73 ? 1001 ASP A CA  1 
ATOM   6930 C C   . ASP A 1 1042 ? 149.863 124.607 93.922  1.00 106.73 ? 1001 ASP A C   1 
ATOM   6931 O O   . ASP A 1 1042 ? 151.057 124.692 94.226  1.00 106.73 ? 1001 ASP A O   1 
ATOM   6932 C CB  . ASP A 1 1042 ? 148.977 124.629 96.258  1.00 106.73 ? 1001 ASP A CB  1 
ATOM   6933 C CG  . ASP A 1 1042 ? 148.215 125.420 97.301  1.00 106.73 ? 1001 ASP A CG  1 
ATOM   6934 O OD1 . ASP A 1 1042 ? 148.466 126.637 97.423  1.00 106.73 ? 1001 ASP A OD1 1 
ATOM   6935 O OD2 . ASP A 1 1042 ? 147.366 124.828 98.000  1.00 106.73 ? 1001 ASP A OD2 1 
ATOM   6936 N N   . ARG A 1 1043 ? 149.453 124.002 92.810  1.00 103.22 ? 1002 ARG A N   1 
ATOM   6937 C CA  . ARG A 1 1043 ? 150.413 123.498 91.838  1.00 103.22 ? 1002 ARG A CA  1 
ATOM   6938 C C   . ARG A 1 1043 ? 151.219 124.653 91.257  1.00 103.22 ? 1002 ARG A C   1 
ATOM   6939 O O   . ARG A 1 1043 ? 150.681 125.732 90.994  1.00 103.22 ? 1002 ARG A O   1 
ATOM   6940 C CB  . ARG A 1 1043 ? 149.688 122.736 90.730  1.00 103.22 ? 1002 ARG A CB  1 
ATOM   6941 C CG  . ARG A 1 1043 ? 150.556 121.762 89.950  1.00 103.22 ? 1002 ARG A CG  1 
ATOM   6942 C CD  . ARG A 1 1043 ? 151.182 122.422 88.735  1.00 103.22 ? 1002 ARG A CD  1 
ATOM   6943 N NE  . ARG A 1 1043 ? 152.008 121.494 87.971  1.00 103.22 ? 1002 ARG A NE  1 
ATOM   6944 C CZ  . ARG A 1 1043 ? 152.638 121.805 86.847  1.00 103.22 ? 1002 ARG A CZ  1 
ATOM   6945 N NH1 . ARG A 1 1043 ? 152.567 123.019 86.327  1.00 103.22 ? 1002 ARG A NH1 1 
ATOM   6946 N NH2 . ARG A 1 1043 ? 153.355 120.872 86.226  1.00 103.22 ? 1002 ARG A NH2 1 
ATOM   6947 N N   . LYS A 1 1044 ? 152.514 124.426 91.061  1.00 107.20 ? 1003 LYS A N   1 
ATOM   6948 C CA  . LYS A 1 1044 ? 153.419 125.449 90.555  1.00 107.20 ? 1003 LYS A CA  1 
ATOM   6949 C C   . LYS A 1 1044 ? 153.741 125.176 89.093  1.00 107.20 ? 1003 LYS A C   1 
ATOM   6950 O O   . LYS A 1 1044 ? 154.089 124.048 88.729  1.00 107.20 ? 1003 LYS A O   1 
ATOM   6951 C CB  . LYS A 1 1044 ? 154.705 125.497 91.379  1.00 107.20 ? 1003 LYS A CB  1 
ATOM   6952 C CG  . LYS A 1 1044 ? 155.560 126.720 91.107  1.00 107.20 ? 1003 LYS A CG  1 
ATOM   6953 C CD  . LYS A 1 1044 ? 154.896 127.981 91.636  1.00 107.20 ? 1003 LYS A CD  1 
ATOM   6954 C CE  . LYS A 1 1044 ? 154.694 127.912 93.140  1.00 107.20 ? 1003 LYS A CE  1 
ATOM   6955 N NZ  . LYS A 1 1044 ? 154.418 129.254 93.720  1.00 107.20 ? 1003 LYS A NZ  1 
ATOM   6956 N N   . THR A 1 1045 ? 153.621 126.207 88.262  1.00 109.89 ? 1004 THR A N   1 
ATOM   6957 C CA  . THR A 1 1045 ? 153.920 126.074 86.844  1.00 109.89 ? 1004 THR A CA  1 
ATOM   6958 C C   . THR A 1 1045 ? 155.404 126.306 86.584  1.00 109.89 ? 1004 THR A C   1 
ATOM   6959 O O   . THR A 1 1045 ? 156.021 127.209 87.155  1.00 109.89 ? 1004 THR A O   1 
ATOM   6960 C CB  . THR A 1 1045 ? 153.073 127.049 86.022  1.00 109.89 ? 1004 THR A CB  1 
ATOM   6961 O OG1 . THR A 1 1045 ? 153.343 126.866 84.627  1.00 109.89 ? 1004 THR A OG1 1 
ATOM   6962 C CG2 . THR A 1 1045 ? 153.353 128.494 86.412  1.00 109.89 ? 1004 THR A CG2 1 
ATOM   6963 N N   . GLU A 1 1046 ? 155.983 125.458 85.732  1.00 114.67 ? 1005 GLU A N   1 
ATOM   6964 C CA  . GLU A 1 1046 ? 157.376 125.646 85.343  1.00 114.67 ? 1005 GLU A CA  1 
ATOM   6965 C C   . GLU A 1 1046 ? 157.531 126.835 84.404  1.00 114.67 ? 1005 GLU A C   1 
ATOM   6966 O O   . GLU A 1 1046 ? 158.451 127.644 84.564  1.00 114.67 ? 1005 GLU A O   1 
ATOM   6967 C CB  . GLU A 1 1046 ? 157.919 124.372 84.697  1.00 114.67 ? 1005 GLU A CB  1 
ATOM   6968 C CG  . GLU A 1 1046 ? 158.038 123.194 85.651  1.00 114.67 ? 1005 GLU A CG  1 
ATOM   6969 C CD  . GLU A 1 1046 ? 156.730 122.454 85.838  1.00 114.67 ? 1005 GLU A CD  1 
ATOM   6970 O OE1 . GLU A 1 1046 ? 155.739 122.821 85.178  1.00 114.67 ? 1005 GLU A OE1 1 
ATOM   6971 O OE2 . GLU A 1 1046 ? 156.695 121.506 86.649  1.00 114.67 ? 1005 GLU A OE2 1 
ATOM   6972 N N   . ILE A 1 1047 ? 156.641 126.960 83.425  1.00 121.65 ? 1006 ILE A N   1 
ATOM   6973 C CA  . ILE A 1 1047 ? 156.648 128.071 82.483  1.00 121.65 ? 1006 ILE A CA  1 
ATOM   6974 C C   . ILE A 1 1047 ? 155.557 129.046 82.893  1.00 121.65 ? 1006 ILE A C   1 
ATOM   6975 O O   . ILE A 1 1047 ? 154.369 128.698 82.888  1.00 121.65 ? 1006 ILE A O   1 
ATOM   6976 C CB  . ILE A 1 1047 ? 156.439 127.587 81.038  1.00 121.65 ? 1006 ILE A CB  1 
ATOM   6977 C CG1 . ILE A 1 1047 ? 157.585 126.668 80.617  1.00 121.65 ? 1006 ILE A CG1 1 
ATOM   6978 C CG2 . ILE A 1 1047 ? 156.329 128.772 80.094  1.00 121.65 ? 1006 ILE A CG2 1 
ATOM   6979 C CD1 . ILE A 1 1047 ? 157.160 125.541 79.713  1.00 121.65 ? 1006 ILE A CD1 1 
ATOM   6980 N N   . GLU A 1 1048 ? 155.956 130.259 83.249  1.00 128.19 ? 1007 GLU A N   1 
ATOM   6981 C CA  . GLU A 1 1048 ? 155.001 131.261 83.695  1.00 128.19 ? 1007 GLU A CA  1 
ATOM   6982 C C   . GLU A 1 1048 ? 154.499 132.063 82.501  1.00 128.19 ? 1007 GLU A C   1 
ATOM   6983 O O   . GLU A 1 1048 ? 155.288 132.775 81.870  1.00 128.19 ? 1007 GLU A O   1 
ATOM   6984 C CB  . GLU A 1 1048 ? 155.633 132.186 84.730  1.00 128.19 ? 1007 GLU A CB  1 
ATOM   6985 C CG  . GLU A 1 1048 ? 157.073 132.598 84.438  1.00 128.19 ? 1007 GLU A CG  1 
ATOM   6986 C CD  . GLU A 1 1048 ? 158.097 131.600 84.955  1.00 128.19 ? 1007 GLU A CD  1 
ATOM   6987 O OE1 . GLU A 1 1048 ? 159.221 132.026 85.295  1.00 128.19 ? 1007 GLU A OE1 1 
ATOM   6988 O OE2 . GLU A 1 1048 ? 157.781 130.394 85.019  1.00 128.19 ? 1007 GLU A OE2 1 
ATOM   6989 N N   . PRO A 1 1049 ? 153.214 131.968 82.148  1.00 132.89 ? 1008 PRO A N   1 
ATOM   6990 C CA  . PRO A 1 1049 ? 152.710 132.790 81.036  1.00 132.89 ? 1008 PRO A CA  1 
ATOM   6991 C C   . PRO A 1 1049 ? 152.844 134.275 81.301  1.00 132.89 ? 1008 PRO A C   1 
ATOM   6992 O O   . PRO A 1 1049 ? 153.066 135.052 80.364  1.00 132.89 ? 1008 PRO A O   1 
ATOM   6993 C CB  . PRO A 1 1049 ? 151.244 132.355 80.915  1.00 132.89 ? 1008 PRO A CB  1 
ATOM   6994 C CG  . PRO A 1 1049 ? 150.898 131.808 82.258  1.00 132.89 ? 1008 PRO A CG  1 
ATOM   6995 C CD  . PRO A 1 1049 ? 152.149 131.180 82.789  1.00 132.89 ? 1008 PRO A CD  1 
ATOM   6996 N N   . ASP A 1 1050 ? 152.716 134.691 82.556  1.00 148.26 ? 1009 ASP A N   1 
ATOM   6997 C CA  . ASP A 1 1050 ? 152.922 136.078 82.928  1.00 148.26 ? 1009 ASP A CA  1 
ATOM   6998 C C   . ASP A 1 1050 ? 154.415 136.397 82.918  1.00 148.26 ? 1009 ASP A C   1 
ATOM   6999 O O   . ASP A 1 1050 ? 155.269 135.508 82.873  1.00 148.26 ? 1009 ASP A O   1 
ATOM   7000 C CB  . ASP A 1 1050 ? 152.307 136.352 84.300  1.00 148.26 ? 1009 ASP A CB  1 
ATOM   7001 C CG  . ASP A 1 1050 ? 152.362 137.814 84.685  1.00 148.26 ? 1009 ASP A CG  1 
ATOM   7002 O OD1 . ASP A 1 1050 ? 151.577 138.606 84.124  1.00 148.26 ? 1009 ASP A OD1 1 
ATOM   7003 O OD2 . ASP A 1 1050 ? 153.192 138.173 85.546  1.00 148.26 ? 1009 ASP A OD2 1 
ATOM   7004 N N   . ASP A 1 1051 ? 154.730 137.688 82.962  1.00 158.83 ? 1010 ASP A N   1 
ATOM   7005 C CA  . ASP A 1 1051 ? 156.105 138.178 82.887  1.00 158.83 ? 1010 ASP A CA  1 
ATOM   7006 C C   . ASP A 1 1051 ? 156.396 139.070 84.088  1.00 158.83 ? 1010 ASP A C   1 
ATOM   7007 O O   . ASP A 1 1051 ? 156.424 140.302 83.976  1.00 158.83 ? 1010 ASP A O   1 
ATOM   7008 C CB  . ASP A 1 1051 ? 156.337 138.920 81.570  1.00 158.83 ? 1010 ASP A CB  1 
ATOM   7009 C CG  . ASP A 1 1051 ? 155.195 139.858 81.221  1.00 158.83 ? 1010 ASP A CG  1 
ATOM   7010 O OD1 . ASP A 1 1051 ? 154.183 139.862 81.954  1.00 158.83 ? 1010 ASP A OD1 1 
ATOM   7011 O OD2 . ASP A 1 1051 ? 155.304 140.588 80.214  1.00 158.83 ? 1010 ASP A OD2 1 
ATOM   7012 N N   . PRO A 1 1052 ? 156.605 138.472 85.264  1.00 164.17 ? 1011 PRO A N   1 
ATOM   7013 C CA  . PRO A 1 1052 ? 156.933 139.293 86.446  1.00 164.17 ? 1011 PRO A CA  1 
ATOM   7014 C C   . PRO A 1 1052 ? 158.206 140.105 86.278  1.00 164.17 ? 1011 PRO A C   1 
ATOM   7015 O O   . PRO A 1 1052 ? 158.275 141.251 86.739  1.00 164.17 ? 1011 PRO A O   1 
ATOM   7016 C CB  . PRO A 1 1052 ? 157.053 138.250 87.568  1.00 164.17 ? 1011 PRO A CB  1 
ATOM   7017 C CG  . PRO A 1 1052 ? 156.317 137.045 87.063  1.00 164.17 ? 1011 PRO A CG  1 
ATOM   7018 C CD  . PRO A 1 1052 ? 156.546 137.038 85.588  1.00 164.17 ? 1011 PRO A CD  1 
ATOM   7019 N N   . ASP A 1 1053 ? 159.223 139.538 85.627  1.00 169.20 ? 1012 ASP A N   1 
ATOM   7020 C CA  . ASP A 1 1053 ? 160.466 140.257 85.346  1.00 169.20 ? 1012 ASP A CA  1 
ATOM   7021 C C   . ASP A 1 1053 ? 160.366 140.850 83.943  1.00 169.20 ? 1012 ASP A C   1 
ATOM   7022 O O   . ASP A 1 1053 ? 160.739 140.239 82.938  1.00 169.20 ? 1012 ASP A O   1 
ATOM   7023 C CB  . ASP A 1 1053 ? 161.672 139.337 85.490  1.00 169.20 ? 1012 ASP A CB  1 
ATOM   7024 C CG  . ASP A 1 1053 ? 161.853 138.832 86.908  1.00 169.20 ? 1012 ASP A CG  1 
ATOM   7025 O OD1 . ASP A 1 1053 ? 161.034 139.195 87.779  1.00 169.20 ? 1012 ASP A OD1 1 
ATOM   7026 O OD2 . ASP A 1 1053 ? 162.815 138.075 87.153  1.00 169.20 ? 1012 ASP A OD2 1 
ATOM   7027 N N   . THR A 1 1054 ? 159.842 142.070 83.887  1.00 169.86 ? 1013 THR A N   1 
ATOM   7028 C CA  . THR A 1 1054 ? 159.635 142.738 82.610  1.00 169.86 ? 1013 THR A CA  1 
ATOM   7029 C C   . THR A 1 1054 ? 160.968 143.045 81.938  1.00 169.86 ? 1013 THR A C   1 
ATOM   7030 O O   . THR A 1 1054 ? 161.922 143.490 82.582  1.00 169.86 ? 1013 THR A O   1 
ATOM   7031 C CB  . THR A 1 1054 ? 158.838 144.028 82.813  1.00 169.86 ? 1013 THR A CB  1 
ATOM   7032 O OG1 . THR A 1 1054 ? 157.638 143.740 83.543  1.00 169.86 ? 1013 THR A OG1 1 
ATOM   7033 C CG2 . THR A 1 1054 ? 158.471 144.653 81.474  1.00 169.86 ? 1013 THR A CG2 1 
ATOM   7034 N N   . THR A 1 1055 ? 161.027 142.801 80.636  1.00 166.70 ? 1014 THR A N   1 
ATOM   7035 C CA  . THR A 1 1055 ? 162.168 143.127 79.800  1.00 166.70 ? 1014 THR A CA  1 
ATOM   7036 C C   . THR A 1 1055 ? 161.715 144.018 78.653  1.00 166.70 ? 1014 THR A C   1 
ATOM   7037 O O   . THR A 1 1055 ? 160.548 143.972 78.246  1.00 166.70 ? 1014 THR A O   1 
ATOM   7038 C CB  . THR A 1 1055 ? 162.828 141.857 79.243  1.00 166.70 ? 1014 THR A CB  1 
ATOM   7039 O OG1 . THR A 1 1055 ? 161.818 140.945 78.796  1.00 166.70 ? 1014 THR A OG1 1 
ATOM   7040 C CG2 . THR A 1 1055 ? 163.675 141.191 80.311  1.00 166.70 ? 1014 THR A CG2 1 
ATOM   7041 N N   . PRO A 1 1056 ? 162.603 144.858 78.124  1.00 168.19 ? 1015 PRO A N   1 
ATOM   7042 C CA  . PRO A 1 1056 ? 162.207 145.759 77.036  1.00 168.19 ? 1015 PRO A CA  1 
ATOM   7043 C C   . PRO A 1 1056 ? 161.643 144.995 75.848  1.00 168.19 ? 1015 PRO A C   1 
ATOM   7044 O O   . PRO A 1 1056 ? 162.181 143.965 75.433  1.00 168.19 ? 1015 PRO A O   1 
ATOM   7045 C CB  . PRO A 1 1056 ? 163.515 146.472 76.680  1.00 168.19 ? 1015 PRO A CB  1 
ATOM   7046 C CG  . PRO A 1 1056 ? 164.306 146.443 77.939  1.00 168.19 ? 1015 PRO A CG  1 
ATOM   7047 C CD  . PRO A 1 1056 ? 163.966 145.140 78.607  1.00 168.19 ? 1015 PRO A CD  1 
ATOM   7048 N N   . VAL A 1 1057 ? 160.544 145.506 75.303  1.00 167.24 ? 1016 VAL A N   1 
ATOM   7049 C CA  . VAL A 1 1057 ? 159.871 144.879 74.170  1.00 167.24 ? 1016 VAL A CA  1 
ATOM   7050 C C   . VAL A 1 1057 ? 159.679 145.923 73.078  1.00 167.24 ? 1016 VAL A C   1 
ATOM   7051 O O   . VAL A 1 1057 ? 158.954 146.907 73.284  1.00 167.24 ? 1016 VAL A O   1 
ATOM   7052 C CB  . VAL A 1 1057 ? 158.528 144.264 74.591  1.00 167.24 ? 1016 VAL A CB  1 
ATOM   7053 C CG1 . VAL A 1 1057 ? 157.715 143.875 73.365  1.00 167.24 ? 1016 VAL A CG1 1 
ATOM   7054 C CG2 . VAL A 1 1057 ? 158.751 143.066 75.496  1.00 167.24 ? 1016 VAL A CG2 1 
ATOM   7055 N N   . PRO A 1 1058 ? 160.311 145.765 71.917  1.00 169.60 ? 1017 PRO A N   1 
ATOM   7056 C CA  . PRO A 1 1058 ? 160.086 146.718 70.827  1.00 169.60 ? 1017 PRO A CA  1 
ATOM   7057 C C   . PRO A 1 1058 ? 158.651 146.661 70.331  1.00 169.60 ? 1017 PRO A C   1 
ATOM   7058 O O   . PRO A 1 1058 ? 157.990 145.620 70.380  1.00 169.60 ? 1017 PRO A O   1 
ATOM   7059 C CB  . PRO A 1 1058 ? 161.071 146.263 69.743  1.00 169.60 ? 1017 PRO A CB  1 
ATOM   7060 C CG  . PRO A 1 1058 ? 161.331 144.831 70.047  1.00 169.60 ? 1017 PRO A CG  1 
ATOM   7061 C CD  . PRO A 1 1058 ? 161.250 144.698 71.538  1.00 169.60 ? 1017 PRO A CD  1 
ATOM   7062 N N   . ASP A 1 1059 ? 158.169 147.812 69.855  1.00 170.88 ? 1018 ASP A N   1 
ATOM   7063 C CA  . ASP A 1 1059 ? 156.800 147.890 69.357  1.00 170.88 ? 1018 ASP A CA  1 
ATOM   7064 C C   . ASP A 1 1059 ? 156.596 146.981 68.152  1.00 170.88 ? 1018 ASP A C   1 
ATOM   7065 O O   . ASP A 1 1059 ? 155.563 146.313 68.038  1.00 170.88 ? 1018 ASP A O   1 
ATOM   7066 C CB  . ASP A 1 1059 ? 156.455 149.337 69.007  1.00 170.88 ? 1018 ASP A CB  1 
ATOM   7067 C CG  . ASP A 1 1059 ? 157.575 150.038 68.264  1.00 170.88 ? 1018 ASP A CG  1 
ATOM   7068 O OD1 . ASP A 1 1059 ? 158.620 149.398 68.020  1.00 170.88 ? 1018 ASP A OD1 1 
ATOM   7069 O OD2 . ASP A 1 1059 ? 157.413 151.229 67.926  1.00 170.88 ? 1018 ASP A OD2 1 
ATOM   7070 N N   . ARG A 1 1060 ? 157.570 146.940 67.246  1.00 164.83 ? 1019 ARG A N   1 
ATOM   7071 C CA  . ARG A 1 1060 ? 157.522 146.088 66.061  1.00 164.83 ? 1019 ARG A CA  1 
ATOM   7072 C C   . ARG A 1 1060 ? 158.754 145.188 66.083  1.00 164.83 ? 1019 ARG A C   1 
ATOM   7073 O O   . ARG A 1 1060 ? 159.799 145.529 65.524  1.00 164.83 ? 1019 ARG A O   1 
ATOM   7074 C CB  . ARG A 1 1060 ? 157.451 146.920 64.781  1.00 164.83 ? 1019 ARG A CB  1 
ATOM   7075 C CG  . ARG A 1 1060 ? 156.096 147.571 64.535  1.00 164.83 ? 1019 ARG A CG  1 
ATOM   7076 C CD  . ARG A 1 1060 ? 155.028 146.537 64.202  1.00 164.83 ? 1019 ARG A CD  1 
ATOM   7077 N NE  . ARG A 1 1060 ? 154.329 146.062 65.390  1.00 164.83 ? 1019 ARG A NE  1 
ATOM   7078 C CZ  . ARG A 1 1060 ? 153.402 145.113 65.387  1.00 164.83 ? 1019 ARG A CZ  1 
ATOM   7079 N NH1 . ARG A 1 1060 ? 153.036 144.509 64.268  1.00 164.83 ? 1019 ARG A NH1 1 
ATOM   7080 N NH2 . ARG A 1 1060 ? 152.831 144.761 66.534  1.00 164.83 ? 1019 ARG A NH2 1 
ATOM   7081 N N   . LEU A 1 1061 ? 158.624 144.035 66.734  1.00 164.58 ? 1020 LEU A N   1 
ATOM   7082 C CA  . LEU A 1 1061 ? 159.707 143.062 66.804  1.00 164.58 ? 1020 LEU A CA  1 
ATOM   7083 C C   . LEU A 1 1061 ? 159.914 142.439 65.431  1.00 164.58 ? 1020 LEU A C   1 
ATOM   7084 O O   . LEU A 1 1061 ? 159.035 141.736 64.922  1.00 164.58 ? 1020 LEU A O   1 
ATOM   7085 C CB  . LEU A 1 1061 ? 159.384 141.996 67.845  1.00 164.58 ? 1020 LEU A CB  1 
ATOM   7086 C CG  . LEU A 1 1061 ? 160.432 140.905 68.059  1.00 164.58 ? 1020 LEU A CG  1 
ATOM   7087 C CD1 . LEU A 1 1061 ? 161.677 141.484 68.703  1.00 164.58 ? 1020 LEU A CD1 1 
ATOM   7088 C CD2 . LEU A 1 1061 ? 159.859 139.783 68.907  1.00 164.58 ? 1020 LEU A CD2 1 
ATOM   7089 N N   . ARG A 1 1062 ? 161.078 142.692 64.825  1.00 164.16 ? 1021 ARG A N   1 
ATOM   7090 C CA  . ARG A 1 1062 ? 161.341 142.162 63.491  1.00 164.16 ? 1021 ARG A CA  1 
ATOM   7091 C C   . ARG A 1 1062 ? 161.442 140.642 63.510  1.00 164.16 ? 1021 ARG A C   1 
ATOM   7092 O O   . ARG A 1 1062 ? 161.015 139.971 62.563  1.00 164.16 ? 1021 ARG A O   1 
ATOM   7093 C CB  . ARG A 1 1062 ? 162.611 142.787 62.917  1.00 164.16 ? 1021 ARG A CB  1 
ATOM   7094 C CG  . ARG A 1 1062 ? 162.917 142.370 61.488  1.00 164.16 ? 1021 ARG A CG  1 
ATOM   7095 C CD  . ARG A 1 1062 ? 161.717 142.575 60.570  1.00 164.16 ? 1021 ARG A CD  1 
ATOM   7096 N NE  . ARG A 1 1062 ? 160.945 141.351 60.390  1.00 164.16 ? 1021 ARG A NE  1 
ATOM   7097 C CZ  . ARG A 1 1062 ? 159.788 141.281 59.746  1.00 164.16 ? 1021 ARG A CZ  1 
ATOM   7098 N NH1 . ARG A 1 1062 ? 159.231 142.353 59.207  1.00 164.16 ? 1021 ARG A NH1 1 
ATOM   7099 N NH2 . ARG A 1 1062 ? 159.174 140.107 59.640  1.00 164.16 ? 1021 ARG A NH2 1 
ATOM   7100 N N   . GLY A 1 1063 ? 162.004 140.079 64.577  1.00 168.34 ? 1022 GLY A N   1 
ATOM   7101 C CA  . GLY A 1 1063 ? 161.982 138.641 64.764  1.00 168.34 ? 1022 GLY A CA  1 
ATOM   7102 C C   . GLY A 1 1063 ? 163.034 137.856 64.010  1.00 168.34 ? 1022 GLY A C   1 
ATOM   7103 O O   . GLY A 1 1063 ? 162.704 137.025 63.159  1.00 168.34 ? 1022 GLY A O   1 
ATOM   7104 N N   . GLU A 1 1064 ? 164.308 138.110 64.309  1.00 169.89 ? 1023 GLU A N   1 
ATOM   7105 C CA  . GLU A 1 1064 ? 165.405 137.320 63.752  1.00 169.89 ? 1023 GLU A CA  1 
ATOM   7106 C C   . GLU A 1 1064 ? 165.598 136.084 64.628  1.00 169.89 ? 1023 GLU A C   1 
ATOM   7107 O O   . GLU A 1 1064 ? 166.497 136.004 65.469  1.00 169.89 ? 1023 GLU A O   1 
ATOM   7108 C CB  . GLU A 1 1064 ? 166.677 138.153 63.659  1.00 169.89 ? 1023 GLU A CB  1 
ATOM   7109 C CG  . GLU A 1 1064 ? 167.760 137.536 62.789  1.00 169.89 ? 1023 GLU A CG  1 
ATOM   7110 C CD  . GLU A 1 1064 ? 169.096 138.233 62.943  1.00 169.89 ? 1023 GLU A CD  1 
ATOM   7111 O OE1 . GLU A 1 1064 ? 169.629 138.257 64.071  1.00 169.89 ? 1023 GLU A OE1 1 
ATOM   7112 O OE2 . GLU A 1 1064 ? 169.612 138.758 61.934  1.00 169.89 ? 1023 GLU A OE2 1 
ATOM   7113 N N   . VAL A 1 1065 ? 164.721 135.100 64.421  1.00 169.69 ? 1024 VAL A N   1 
ATOM   7114 C CA  . VAL A 1 1065 ? 164.745 133.886 65.228  1.00 169.69 ? 1024 VAL A CA  1 
ATOM   7115 C C   . VAL A 1 1065 ? 165.976 133.056 64.891  1.00 169.69 ? 1024 VAL A C   1 
ATOM   7116 O O   . VAL A 1 1065 ? 166.387 132.954 63.727  1.00 169.69 ? 1024 VAL A O   1 
ATOM   7117 C CB  . VAL A 1 1065 ? 163.444 133.087 65.025  1.00 169.69 ? 1024 VAL A CB  1 
ATOM   7118 C CG1 . VAL A 1 1065 ? 163.357 132.537 63.612  1.00 169.69 ? 1024 VAL A CG1 1 
ATOM   7119 C CG2 . VAL A 1 1065 ? 163.354 131.955 66.032  1.00 169.69 ? 1024 VAL A CG2 1 
ATOM   7120 N N   . GLU A 1 1066 ? 166.582 132.459 65.924  1.00 170.74 ? 1025 GLU A N   1 
ATOM   7121 C CA  . GLU A 1 1066 ? 167.772 131.590 65.714  1.00 170.74 ? 1025 GLU A CA  1 
ATOM   7122 C C   . GLU A 1 1066 ? 167.771 130.464 66.754  1.00 170.74 ? 1025 GLU A C   1 
ATOM   7123 O O   . GLU A 1 1066 ? 168.218 130.714 67.890  1.00 170.74 ? 1025 GLU A O   1 
ATOM   7124 C CB  . GLU A 1 1066 ? 169.069 132.397 65.817  1.00 170.74 ? 1025 GLU A CB  1 
ATOM   7125 C CG  . GLU A 1 1066 ? 169.404 133.178 64.561  1.00 170.74 ? 1025 GLU A CG  1 
ATOM   7126 C CD  . GLU A 1 1066 ? 170.827 133.706 64.505  1.00 170.74 ? 1025 GLU A CD  1 
ATOM   7127 O OE1 . GLU A 1 1066 ? 171.197 134.495 65.395  1.00 170.74 ? 1025 GLU A OE1 1 
ATOM   7128 O OE2 . GLU A 1 1066 ? 171.560 133.322 63.573  1.00 170.74 ? 1025 GLU A OE2 1 
ATOM   7129 N N   . LEU A 1 1067 ? 167.287 129.275 66.379  1.00 168.53 ? 1026 LEU A N   1 
ATOM   7130 C CA  . LEU A 1 1067 ? 167.312 128.109 67.302  1.00 168.53 ? 1026 LEU A CA  1 
ATOM   7131 C C   . LEU A 1 1067 ? 168.691 127.452 67.214  1.00 168.53 ? 1026 LEU A C   1 
ATOM   7132 O O   . LEU A 1 1067 ? 168.777 126.358 66.629  1.00 168.53 ? 1026 LEU A O   1 
ATOM   7133 C CB  . LEU A 1 1067 ? 166.218 127.117 66.892  1.00 168.53 ? 1026 LEU A CB  1 
ATOM   7134 C CG  . LEU A 1 1067 ? 164.785 127.644 66.941  1.00 168.53 ? 1026 LEU A CG  1 
ATOM   7135 C CD1 . LEU A 1 1067 ? 164.353 128.180 65.584  1.00 168.53 ? 1026 LEU A CD1 1 
ATOM   7136 C CD2 . LEU A 1 1067 ? 163.828 126.563 67.419  1.00 168.53 ? 1026 LEU A CD2 1 
ATOM   7137 N N   . LYS A 1 1068 ? 169.725 128.093 67.767  1.00 169.92 ? 1027 LYS A N   1 
ATOM   7138 C CA  . LYS A 1 1068 ? 171.108 127.561 67.633  1.00 169.92 ? 1027 LYS A CA  1 
ATOM   7139 C C   . LYS A 1 1068 ? 171.352 126.443 68.651  1.00 169.92 ? 1027 LYS A C   1 
ATOM   7140 O O   . LYS A 1 1068 ? 171.005 126.640 69.832  1.00 169.92 ? 1027 LYS A O   1 
ATOM   7141 C CB  . LYS A 1 1068 ? 172.128 128.688 67.815  1.00 169.92 ? 1027 LYS A CB  1 
ATOM   7142 C CG  . LYS A 1 1068 ? 173.579 128.289 67.581  1.00 169.92 ? 1027 LYS A CG  1 
ATOM   7143 C CD  . LYS A 1 1068 ? 174.554 129.429 67.774  1.00 169.92 ? 1027 LYS A CD  1 
ATOM   7144 C CE  . LYS A 1 1068 ? 175.989 129.030 67.506  1.00 169.92 ? 1027 LYS A CE  1 
ATOM   7145 N NZ  . LYS A 1 1068 ? 176.922 130.163 67.714  1.00 169.92 ? 1027 LYS A NZ  1 
ATOM   7146 N N   . HIS A 1 1069 ? 171.920 125.317 68.205  1.00 171.43 ? 1028 HIS A N   1 
ATOM   7147 C CA  . HIS A 1 1069 ? 172.263 124.198 69.126  1.00 171.43 ? 1028 HIS A CA  1 
ATOM   7148 C C   . HIS A 1 1069 ? 171.097 123.926 70.081  1.00 171.43 ? 1028 HIS A C   1 
ATOM   7149 O O   . HIS A 1 1069 ? 171.320 123.862 71.310  1.00 171.43 ? 1028 HIS A O   1 
ATOM   7150 C CB  . HIS A 1 1069 ? 173.559 124.503 69.886  1.00 171.43 ? 1028 HIS A CB  1 
ATOM   7151 C CG  . HIS A 1 1069 ? 174.754 124.599 68.999  1.00 171.43 ? 1028 HIS A CG  1 
ATOM   7152 N ND1 . HIS A 1 1069 ? 175.173 123.556 68.204  1.00 171.43 ? 1028 HIS A ND1 1 
ATOM   7153 C CD2 . HIS A 1 1069 ? 175.611 125.602 68.777  1.00 171.43 ? 1028 HIS A CD2 1 
ATOM   7154 C CE1 . HIS A 1 1069 ? 176.252 123.927 67.530  1.00 171.43 ? 1028 HIS A CE1 1 
ATOM   7155 N NE2 . HIS A 1 1069 ? 176.535 125.168 67.862  1.00 171.43 ? 1028 HIS A NE2 1 
ATOM   7156 N N   . ILE A 1 1070 ? 169.892 123.756 69.533  1.00 167.42 ? 1029 ILE A N   1 
ATOM   7157 C CA  . ILE A 1 1070 ? 168.714 123.429 70.390  1.00 167.42 ? 1029 ILE A CA  1 
ATOM   7158 C C   . ILE A 1 1070 ? 168.605 121.906 70.512  1.00 167.42 ? 1029 ILE A C   1 
ATOM   7159 O O   . ILE A 1 1070 ? 168.416 121.242 69.474  1.00 167.42 ? 1029 ILE A O   1 
ATOM   7160 C CB  . ILE A 1 1070 ? 167.426 124.062 69.827  1.00 167.42 ? 1029 ILE A CB  1 
ATOM   7161 C CG1 . ILE A 1 1070 ? 167.440 125.584 69.984  1.00 167.42 ? 1029 ILE A CG1 1 
ATOM   7162 C CG2 . ILE A 1 1070 ? 166.195 123.449 70.476  1.00 167.42 ? 1029 ILE A CG2 1 
ATOM   7163 C CD1 . ILE A 1 1070 ? 167.481 126.042 71.420  1.00 167.42 ? 1029 ILE A CD1 1 
ATOM   7164 N N   . ASP A 1 1071 ? 168.749 121.379 71.730  1.00 161.22 ? 1030 ASP A N   1 
ATOM   7165 C CA  . ASP A 1 1071 ? 168.591 119.919 71.955  1.00 161.22 ? 1030 ASP A CA  1 
ATOM   7166 C C   . ASP A 1 1071 ? 167.245 119.698 72.648  1.00 161.22 ? 1030 ASP A C   1 
ATOM   7167 O O   . ASP A 1 1071 ? 167.176 119.907 73.872  1.00 161.22 ? 1030 ASP A O   1 
ATOM   7168 C CB  . ASP A 1 1071 ? 169.759 119.356 72.769  1.00 161.22 ? 1030 ASP A CB  1 
ATOM   7169 C CG  . ASP A 1 1071 ? 169.811 117.838 72.805  1.00 161.22 ? 1030 ASP A CG  1 
ATOM   7170 O OD1 . ASP A 1 1071 ? 168.940 117.204 72.182  1.00 161.22 ? 1030 ASP A OD1 1 
ATOM   7171 O OD2 . ASP A 1 1071 ? 170.727 117.302 73.459  1.00 161.22 ? 1030 ASP A OD2 1 
ATOM   7172 N N   . PHE A 1 1072 ? 166.217 119.307 71.890  1.00 154.43 ? 1031 PHE A N   1 
ATOM   7173 C CA  . PHE A 1 1072 ? 164.862 119.140 72.478  1.00 154.43 ? 1031 PHE A CA  1 
ATOM   7174 C C   . PHE A 1 1072 ? 164.417 117.680 72.362  1.00 154.43 ? 1031 PHE A C   1 
ATOM   7175 O O   . PHE A 1 1072 ? 164.530 117.102 71.263  1.00 154.43 ? 1031 PHE A O   1 
ATOM   7176 C CB  . PHE A 1 1072 ? 163.853 120.067 71.797  1.00 154.43 ? 1031 PHE A CB  1 
ATOM   7177 C CG  . PHE A 1 1072 ? 162.426 119.851 72.232  1.00 154.43 ? 1031 PHE A CG  1 
ATOM   7178 C CD1 . PHE A 1 1072 ? 162.062 119.979 73.562  1.00 154.43 ? 1031 PHE A CD1 1 
ATOM   7179 C CD2 . PHE A 1 1072 ? 161.446 119.515 71.313  1.00 154.43 ? 1031 PHE A CD2 1 
ATOM   7180 C CE1 . PHE A 1 1072 ? 160.752 119.780 73.962  1.00 154.43 ? 1031 PHE A CE1 1 
ATOM   7181 C CE2 . PHE A 1 1072 ? 160.136 119.314 71.713  1.00 154.43 ? 1031 PHE A CE2 1 
ATOM   7182 C CZ  . PHE A 1 1072 ? 159.790 119.447 73.037  1.00 154.43 ? 1031 PHE A CZ  1 
ATOM   7183 N N   . SER A 1 1073 ? 163.916 117.114 73.462  1.00 156.60 ? 1032 SER A N   1 
ATOM   7184 C CA  . SER A 1 1073 ? 163.425 115.712 73.446  1.00 156.60 ? 1032 SER A CA  1 
ATOM   7185 C C   . SER A 1 1073 ? 161.898 115.703 73.560  1.00 156.60 ? 1032 SER A C   1 
ATOM   7186 O O   . SER A 1 1073 ? 161.358 116.551 74.296  1.00 156.60 ? 1032 SER A O   1 
ATOM   7187 C CB  . SER A 1 1073 ? 164.053 114.911 74.553  1.00 156.60 ? 1032 SER A CB  1 
ATOM   7188 O OG  . SER A 1 1073 ? 163.650 115.406 75.822  1.00 156.60 ? 1032 SER A OG  1 
ATOM   7189 N N   . TYR A 1 1074 ? 161.235 114.776 72.863  1.00 152.65 ? 1033 TYR A N   1 
ATOM   7190 C CA  . TYR A 1 1074 ? 159.757 114.655 72.949  1.00 152.65 ? 1033 TYR A CA  1 
ATOM   7191 C C   . TYR A 1 1074 ? 159.352 114.720 74.425  1.00 152.65 ? 1033 TYR A C   1 
ATOM   7192 O O   . TYR A 1 1074 ? 159.831 113.886 75.214  1.00 152.65 ? 1033 TYR A O   1 
ATOM   7193 C CB  . TYR A 1 1074 ? 159.322 113.340 72.298  1.00 152.65 ? 1033 TYR A CB  1 
ATOM   7194 C CG  . TYR A 1 1074 ? 157.847 113.174 72.033  1.00 152.65 ? 1033 TYR A CG  1 
ATOM   7195 C CD1 . TYR A 1 1074 ? 156.944 114.191 72.289  1.00 152.65 ? 1033 TYR A CD1 1 
ATOM   7196 C CD2 . TYR A 1 1074 ? 157.351 111.986 71.523  1.00 152.65 ? 1033 TYR A CD2 1 
ATOM   7197 C CE1 . TYR A 1 1074 ? 155.590 114.037 72.046  1.00 152.65 ? 1033 TYR A CE1 1 
ATOM   7198 C CE2 . TYR A 1 1074 ? 156.001 111.813 71.274  1.00 152.65 ? 1033 TYR A CE2 1 
ATOM   7199 C CZ  . TYR A 1 1074 ? 155.115 112.842 71.536  1.00 152.65 ? 1033 TYR A CZ  1 
ATOM   7200 O OH  . TYR A 1 1074 ? 153.773 112.678 71.291  1.00 152.65 ? 1033 TYR A OH  1 
ATOM   7201 N N   . PRO A 1 1075 ? 158.493 115.676 74.845  1.00 151.60 ? 1034 PRO A N   1 
ATOM   7202 C CA  . PRO A 1 1075 ? 158.029 115.736 76.233  1.00 151.60 ? 1034 PRO A CA  1 
ATOM   7203 C C   . PRO A 1 1075 ? 157.334 114.426 76.631  1.00 151.60 ? 1034 PRO A C   1 
ATOM   7204 O O   . PRO A 1 1075 ? 157.614 113.924 77.704  1.00 151.60 ? 1034 PRO A O   1 
ATOM   7205 C CB  . PRO A 1 1075 ? 157.025 116.900 76.246  1.00 151.60 ? 1034 PRO A CB  1 
ATOM   7206 C CG  . PRO A 1 1075 ? 156.683 117.129 74.788  1.00 151.60 ? 1034 PRO A CG  1 
ATOM   7207 C CD  . PRO A 1 1075 ? 157.937 116.754 74.028  1.00 151.60 ? 1034 PRO A CD  1 
ATOM   7208 N N   . SER A 1 1076 ? 156.462 113.905 75.762  1.00 154.40 ? 1035 SER A N   1 
ATOM   7209 C CA  . SER A 1 1076 ? 155.754 112.630 76.049  1.00 154.40 ? 1035 SER A CA  1 
ATOM   7210 C C   . SER A 1 1076 ? 156.758 111.473 76.087  1.00 154.40 ? 1035 SER A C   1 
ATOM   7211 O O   . SER A 1 1076 ? 156.641 110.624 76.993  1.00 154.40 ? 1035 SER A O   1 
ATOM   7212 C CB  . SER A 1 1076 ? 154.667 112.377 75.040  1.00 154.40 ? 1035 SER A CB  1 
ATOM   7213 O OG  . SER A 1 1076 ? 154.069 111.107 75.252  1.00 154.40 ? 1035 SER A OG  1 
ATOM   7214 N N   . ARG A 1 1077 ? 157.702 111.445 75.142  1.00 156.09 ? 1036 ARG A N   1 
ATOM   7215 C CA  . ARG A 1 1077 ? 158.698 110.341 75.075  1.00 156.09 ? 1036 ARG A CA  1 
ATOM   7216 C C   . ARG A 1 1077 ? 160.108 110.925 75.203  1.00 156.09 ? 1036 ARG A C   1 
ATOM   7217 O O   . ARG A 1 1077 ? 160.721 111.219 74.159  1.00 156.09 ? 1036 ARG A O   1 
ATOM   7218 C CB  . ARG A 1 1077 ? 158.538 109.567 73.764  1.00 156.09 ? 1036 ARG A CB  1 
ATOM   7219 C CG  . ARG A 1 1077 ? 158.045 108.139 73.938  1.00 156.09 ? 1036 ARG A CG  1 
ATOM   7220 C CD  . ARG A 1 1077 ? 156.786 108.043 74.782  1.00 156.09 ? 1036 ARG A CD  1 
ATOM   7221 N NE  . ARG A 1 1077 ? 155.678 108.860 74.301  1.00 156.09 ? 1036 ARG A NE  1 
ATOM   7222 C CZ  . ARG A 1 1077 ? 155.056 108.696 73.139  1.00 156.09 ? 1036 ARG A CZ  1 
ATOM   7223 N NH1 . ARG A 1 1077 ? 155.329 107.652 72.378  1.00 156.09 ? 1036 ARG A NH1 1 
ATOM   7224 N NH2 . ARG A 1 1077 ? 154.149 109.575 72.749  1.00 156.09 ? 1036 ARG A NH2 1 
ATOM   7225 N N   . PRO A 1 1078 ? 160.660 111.081 76.425  1.00 158.42 ? 1037 PRO A N   1 
ATOM   7226 C CA  . PRO A 1 1078 ? 161.974 111.709 76.609  1.00 158.42 ? 1037 PRO A CA  1 
ATOM   7227 C C   . PRO A 1 1078 ? 163.056 111.050 75.742  1.00 158.42 ? 1037 PRO A C   1 
ATOM   7228 O O   . PRO A 1 1078 ? 163.916 111.755 75.249  1.00 158.42 ? 1037 PRO A O   1 
ATOM   7229 C CB  . PRO A 1 1078 ? 162.275 111.461 78.093  1.00 158.42 ? 1037 PRO A CB  1 
ATOM   7230 C CG  . PRO A 1 1078 ? 160.908 111.364 78.731  1.00 158.42 ? 1037 PRO A CG  1 
ATOM   7231 C CD  . PRO A 1 1078 ? 160.049 110.673 77.693  1.00 158.42 ? 1037 PRO A CD  1 
ATOM   7232 N N   . ASP A 1 1079 ? 162.985 109.726 75.577  1.00 161.36 ? 1038 ASP A N   1 
ATOM   7233 C CA  . ASP A 1 1079 ? 163.988 108.998 74.755  1.00 161.36 ? 1038 ASP A CA  1 
ATOM   7234 C C   . ASP A 1 1079 ? 164.021 109.606 73.349  1.00 161.36 ? 1038 ASP A C   1 
ATOM   7235 O O   . ASP A 1 1079 ? 165.131 109.820 72.824  1.00 161.36 ? 1038 ASP A O   1 
ATOM   7236 C CB  . ASP A 1 1079 ? 163.703 107.494 74.729  1.00 161.36 ? 1038 ASP A CB  1 
ATOM   7237 C CG  . ASP A 1 1079 ? 162.261 107.149 74.395  1.00 161.36 ? 1038 ASP A CG  1 
ATOM   7238 O OD1 . ASP A 1 1079 ? 161.463 108.085 74.198  1.00 161.36 ? 1038 ASP A OD1 1 
ATOM   7239 O OD2 . ASP A 1 1079 ? 161.948 105.945 74.332  1.00 161.36 ? 1038 ASP A OD2 1 
ATOM   7240 N N   . ILE A 1 1080 ? 162.847 109.880 72.772  1.00 161.51 ? 1039 ILE A N   1 
ATOM   7241 C CA  . ILE A 1 1080 ? 162.775 110.504 71.417  1.00 161.51 ? 1039 ILE A CA  1 
ATOM   7242 C C   . ILE A 1 1080 ? 163.262 111.951 71.522  1.00 161.51 ? 1039 ILE A C   1 
ATOM   7243 O O   . ILE A 1 1080 ? 162.712 112.692 72.354  1.00 161.51 ? 1039 ILE A O   1 
ATOM   7244 C CB  . ILE A 1 1080 ? 161.339 110.429 70.860  1.00 161.51 ? 1039 ILE A CB  1 
ATOM   7245 C CG1 . ILE A 1 1080 ? 160.826 108.988 70.806  1.00 161.51 ? 1039 ILE A CG1 1 
ATOM   7246 C CG2 . ILE A 1 1080 ? 161.249 111.111 69.503  1.00 161.51 ? 1039 ILE A CG2 1 
ATOM   7247 C CD1 . ILE A 1 1080 ? 159.433 108.856 70.236  1.00 161.51 ? 1039 ILE A CD1 1 
ATOM   7248 N N   . GLN A 1 1081 ? 164.256 112.329 70.712  1.00 163.17 ? 1040 GLN A N   1 
ATOM   7249 C CA  . GLN A 1 1081 ? 164.748 113.733 70.703  1.00 163.17 ? 1040 GLN A CA  1 
ATOM   7250 C C   . GLN A 1 1081 ? 164.578 114.304 69.292  1.00 163.17 ? 1040 GLN A C   1 
ATOM   7251 O O   . GLN A 1 1081 ? 165.443 114.029 68.438  1.00 163.17 ? 1040 GLN A O   1 
ATOM   7252 C CB  . GLN A 1 1081 ? 166.209 113.797 71.151  1.00 163.17 ? 1040 GLN A CB  1 
ATOM   7253 C CG  . GLN A 1 1081 ? 166.449 113.199 72.530  1.00 163.17 ? 1040 GLN A CG  1 
ATOM   7254 C CD  . GLN A 1 1081 ? 167.807 113.561 73.077  1.00 163.17 ? 1040 GLN A CD  1 
ATOM   7255 O OE1 . GLN A 1 1081 ? 168.582 114.272 72.443  1.00 163.17 ? 1040 GLN A OE1 1 
ATOM   7256 N NE2 . GLN A 1 1081 ? 168.103 113.075 74.272  1.00 163.17 ? 1040 GLN A NE2 1 
ATOM   7257 N N   . ILE A 1 1082 ? 163.507 115.070 69.066  1.00 164.76 ? 1041 ILE A N   1 
ATOM   7258 C CA  . ILE A 1 1082 ? 163.230 115.628 67.708  1.00 164.76 ? 1041 ILE A CA  1 
ATOM   7259 C C   . ILE A 1 1082 ? 164.353 116.601 67.330  1.00 164.76 ? 1041 ILE A C   1 
ATOM   7260 O O   . ILE A 1 1082 ? 164.651 116.713 66.126  1.00 164.76 ? 1041 ILE A O   1 
ATOM   7261 C CB  . ILE A 1 1082 ? 161.835 116.288 67.665  1.00 164.76 ? 1041 ILE A CB  1 
ATOM   7262 C CG1 . ILE A 1 1082 ? 161.748 117.519 68.570  1.00 164.76 ? 1041 ILE A CG1 1 
ATOM   7263 C CG2 . ILE A 1 1082 ? 160.753 115.272 67.995  1.00 164.76 ? 1041 ILE A CG2 1 
ATOM   7264 C CD1 . ILE A 1 1082 ? 161.977 118.831 67.855  1.00 164.76 ? 1041 ILE A CD1 1 
ATOM   7265 N N   . PHE A 1 1083 ? 164.944 117.276 68.321  1.00 162.19 ? 1042 PHE A N   1 
ATOM   7266 C CA  . PHE A 1 1083 ? 166.047 118.238 68.060  1.00 162.19 ? 1042 PHE A CA  1 
ATOM   7267 C C   . PHE A 1 1083 ? 167.309 117.762 68.785  1.00 162.19 ? 1042 PHE A C   1 
ATOM   7268 O O   . PHE A 1 1083 ? 167.211 117.402 69.972  1.00 162.19 ? 1042 PHE A O   1 
ATOM   7269 C CB  . PHE A 1 1083 ? 165.642 119.646 68.501  1.00 162.19 ? 1042 PHE A CB  1 
ATOM   7270 C CG  . PHE A 1 1083 ? 165.509 120.647 67.382  1.00 162.19 ? 1042 PHE A CG  1 
ATOM   7271 C CD1 . PHE A 1 1083 ? 164.677 120.399 66.303  1.00 162.19 ? 1042 PHE A CD1 1 
ATOM   7272 C CD2 . PHE A 1 1083 ? 166.203 121.846 67.413  1.00 162.19 ? 1042 PHE A CD2 1 
ATOM   7273 C CE1 . PHE A 1 1083 ? 164.553 121.323 65.278  1.00 162.19 ? 1042 PHE A CE1 1 
ATOM   7274 C CE2 . PHE A 1 1083 ? 166.075 122.771 66.389  1.00 162.19 ? 1042 PHE A CE2 1 
ATOM   7275 C CZ  . PHE A 1 1083 ? 165.251 122.507 65.322  1.00 162.19 ? 1042 PHE A CZ  1 
ATOM   7276 N N   . ARG A 1 1084 ? 168.448 117.752 68.086  1.00 169.53 ? 1043 ARG A N   1 
ATOM   7277 C CA  . ARG A 1 1084 ? 169.728 117.298 68.693  1.00 169.53 ? 1043 ARG A CA  1 
ATOM   7278 C C   . ARG A 1 1084 ? 170.783 118.389 68.498  1.00 169.53 ? 1043 ARG A C   1 
ATOM   7279 O O   . ARG A 1 1084 ? 171.591 118.261 67.557  1.00 169.53 ? 1043 ARG A O   1 
ATOM   7280 C CB  . ARG A 1 1084 ? 170.179 115.984 68.050  1.00 169.53 ? 1043 ARG A CB  1 
ATOM   7281 C CG  . ARG A 1 1084 ? 169.402 114.762 68.518  1.00 169.53 ? 1043 ARG A CG  1 
ATOM   7282 C CD  . ARG A 1 1084 ? 170.222 113.913 69.471  1.00 169.53 ? 1043 ARG A CD  1 
ATOM   7283 N NE  . ARG A 1 1084 ? 170.803 114.694 70.552  1.00 169.53 ? 1043 ARG A NE  1 
ATOM   7284 C CZ  . ARG A 1 1084 ? 171.569 114.194 71.515  1.00 169.53 ? 1043 ARG A CZ  1 
ATOM   7285 N NH1 . ARG A 1 1084 ? 172.073 114.991 72.440  1.00 169.53 ? 1043 ARG A NH1 1 
ATOM   7286 N NH2 . ARG A 1 1084 ? 171.826 112.898 71.552  1.00 169.53 ? 1043 ARG A NH2 1 
ATOM   7287 N N   . ASP A 1 1085 ? 170.760 119.426 69.342  1.00 171.85 ? 1044 ASP A N   1 
ATOM   7288 C CA  . ASP A 1 1085 ? 171.712 120.561 69.195  1.00 171.85 ? 1044 ASP A CA  1 
ATOM   7289 C C   . ASP A 1 1085 ? 171.656 121.068 67.751  1.00 171.85 ? 1044 ASP A C   1 
ATOM   7290 O O   . ASP A 1 1085 ? 172.723 121.417 67.206  1.00 171.85 ? 1044 ASP A O   1 
ATOM   7291 C CB  . ASP A 1 1085 ? 173.127 120.176 69.633  1.00 171.85 ? 1044 ASP A CB  1 
ATOM   7292 C CG  . ASP A 1 1085 ? 173.381 120.426 71.109  1.00 171.85 ? 1044 ASP A CG  1 
ATOM   7293 O OD1 . ASP A 1 1085 ? 172.463 120.935 71.782  1.00 171.85 ? 1044 ASP A OD1 1 
ATOM   7294 O OD2 . ASP A 1 1085 ? 174.494 120.109 71.574  1.00 171.85 ? 1044 ASP A OD2 1 
ATOM   7295 N N   . LEU A 1 1086 ? 170.457 121.107 67.164  1.00 171.30 ? 1045 LEU A N   1 
ATOM   7296 C CA  . LEU A 1 1086 ? 170.299 121.617 65.777  1.00 171.30 ? 1045 LEU A CA  1 
ATOM   7297 C C   . LEU A 1 1086 ? 170.432 123.141 65.815  1.00 171.30 ? 1045 LEU A C   1 
ATOM   7298 O O   . LEU A 1 1086 ? 169.681 123.772 66.578  1.00 171.30 ? 1045 LEU A O   1 
ATOM   7299 C CB  . LEU A 1 1086 ? 168.924 121.191 65.252  1.00 171.30 ? 1045 LEU A CB  1 
ATOM   7300 C CG  . LEU A 1 1086 ? 168.785 121.077 63.734  1.00 171.30 ? 1045 LEU A CG  1 
ATOM   7301 C CD1 . LEU A 1 1086 ? 167.477 120.398 63.364  1.00 171.30 ? 1045 LEU A CD1 1 
ATOM   7302 C CD2 . LEU A 1 1086 ? 168.869 122.438 63.065  1.00 171.30 ? 1045 LEU A CD2 1 
ATOM   7303 N N   . SER A 1 1087 ? 171.360 123.697 65.030  1.00 172.94 ? 1046 SER A N   1 
ATOM   7304 C CA  . SER A 1 1087 ? 171.525 125.173 64.961  1.00 172.94 ? 1046 SER A CA  1 
ATOM   7305 C C   . SER A 1 1087 ? 170.611 125.740 63.872  1.00 172.94 ? 1046 SER A C   1 
ATOM   7306 O O   . SER A 1 1087 ? 171.139 126.297 62.890  1.00 172.94 ? 1046 SER A O   1 
ATOM   7307 C CB  . SER A 1 1087 ? 172.964 125.547 64.726  1.00 172.94 ? 1046 SER A CB  1 
ATOM   7308 O OG  . SER A 1 1087 ? 173.770 125.159 65.828  1.00 172.94 ? 1046 SER A OG  1 
ATOM   7309 N N   . LEU A 1 1088 ? 169.293 125.597 64.043  1.00 173.29 ? 1047 LEU A N   1 
ATOM   7310 C CA  . LEU A 1 1088 ? 168.324 126.138 63.054  1.00 173.29 ? 1047 LEU A CA  1 
ATOM   7311 C C   . LEU A 1 1088 ? 168.322 127.666 63.157  1.00 173.29 ? 1047 LEU A C   1 
ATOM   7312 O O   . LEU A 1 1088 ? 168.535 128.180 64.269  1.00 173.29 ? 1047 LEU A O   1 
ATOM   7313 C CB  . LEU A 1 1088 ? 166.938 125.562 63.356  1.00 173.29 ? 1047 LEU A CB  1 
ATOM   7314 C CG  . LEU A 1 1088 ? 165.860 125.869 62.319  1.00 173.29 ? 1047 LEU A CG  1 
ATOM   7315 C CD1 . LEU A 1 1088 ? 166.145 125.143 61.013  1.00 173.29 ? 1047 LEU A CD1 1 
ATOM   7316 C CD2 . LEU A 1 1088 ? 164.482 125.494 62.843  1.00 173.29 ? 1047 LEU A CD2 1 
ATOM   7317 N N   . ARG A 1 1089 ? 168.099 128.360 62.039  1.00 171.57 ? 1048 ARG A N   1 
ATOM   7318 C CA  . ARG A 1 1089 ? 168.016 129.844 62.085  1.00 171.57 ? 1048 ARG A CA  1 
ATOM   7319 C C   . ARG A 1 1089 ? 167.174 130.366 60.919  1.00 171.57 ? 1048 ARG A C   1 
ATOM   7320 O O   . ARG A 1 1089 ? 166.989 129.618 59.938  1.00 171.57 ? 1048 ARG A O   1 
ATOM   7321 C CB  . ARG A 1 1089 ? 169.413 130.473 62.065  1.00 171.57 ? 1048 ARG A CB  1 
ATOM   7322 C CG  . ARG A 1 1089 ? 170.347 129.907 61.007  1.00 171.57 ? 1048 ARG A CG  1 
ATOM   7323 C CD  . ARG A 1 1089 ? 171.560 129.279 61.667  1.00 171.57 ? 1048 ARG A CD  1 
ATOM   7324 N NE  . ARG A 1 1089 ? 172.150 130.171 62.655  1.00 171.57 ? 1048 ARG A NE  1 
ATOM   7325 C CZ  . ARG A 1 1089 ? 172.214 129.911 63.956  1.00 171.57 ? 1048 ARG A CZ  1 
ATOM   7326 N NH1 . ARG A 1 1089 ? 172.867 130.728 64.763  1.00 171.57 ? 1048 ARG A NH1 1 
ATOM   7327 N NH2 . ARG A 1 1089 ? 171.618 128.838 64.445  1.00 171.57 ? 1048 ARG A NH2 1 
ATOM   7328 N N   . ALA A 1 1090 ? 166.690 131.605 61.034  1.00 171.52 ? 1049 ALA A N   1 
ATOM   7329 C CA  . ALA A 1 1090 ? 165.874 132.233 59.969  1.00 171.52 ? 1049 ALA A CA  1 
ATOM   7330 C C   . ALA A 1 1090 ? 166.033 133.755 60.040  1.00 171.52 ? 1049 ALA A C   1 
ATOM   7331 O O   . ALA A 1 1090 ? 165.677 134.339 61.083  1.00 171.52 ? 1049 ALA A O   1 
ATOM   7332 C CB  . ALA A 1 1090 ? 164.431 131.825 60.116  1.00 171.52 ? 1049 ALA A CB  1 
ATOM   7333 N N   . ARG A 1 1091 ? 166.543 134.366 58.967  1.00 168.56 ? 1050 ARG A N   1 
ATOM   7334 C CA  . ARG A 1 1091 ? 166.742 135.840 58.946  1.00 168.56 ? 1050 ARG A CA  1 
ATOM   7335 C C   . ARG A 1 1091 ? 165.376 136.527 59.029  1.00 168.56 ? 1050 ARG A C   1 
ATOM   7336 O O   . ARG A 1 1091 ? 164.443 136.072 58.337  1.00 168.56 ? 1050 ARG A O   1 
ATOM   7337 C CB  . ARG A 1 1091 ? 167.515 136.266 57.695  1.00 168.56 ? 1050 ARG A CB  1 
ATOM   7338 C CG  . ARG A 1 1091 ? 167.781 137.762 57.615  1.00 168.56 ? 1050 ARG A CG  1 
ATOM   7339 C CD  . ARG A 1 1091 ? 168.805 138.116 56.553  1.00 168.56 ? 1050 ARG A CD  1 
ATOM   7340 N NE  . ARG A 1 1091 ? 170.100 137.511 56.829  1.00 168.56 ? 1050 ARG A NE  1 
ATOM   7341 C CZ  . ARG A 1 1091 ? 170.725 136.667 56.017  1.00 168.56 ? 1050 ARG A CZ  1 
ATOM   7342 N NH1 . ARG A 1 1091 ? 170.244 136.431 54.810  1.00 168.56 ? 1050 ARG A NH1 1 
ATOM   7343 N NH2 . ARG A 1 1091 ? 171.831 136.062 56.416  1.00 168.56 ? 1050 ARG A NH2 1 
ATOM   7344 N N   . ALA A 1 1092 ? 165.268 137.576 59.845  1.00 167.48 ? 1051 ALA A N   1 
ATOM   7345 C CA  . ALA A 1 1092 ? 163.983 138.291 60.025  1.00 167.48 ? 1051 ALA A CA  1 
ATOM   7346 C C   . ALA A 1 1092 ? 163.507 138.858 58.684  1.00 167.48 ? 1051 ALA A C   1 
ATOM   7347 O O   . ALA A 1 1092 ? 164.356 139.351 57.915  1.00 167.48 ? 1051 ALA A O   1 
ATOM   7348 C CB  . ALA A 1 1092 ? 164.159 139.379 61.050  1.00 167.48 ? 1051 ALA A CB  1 
ATOM   7349 N N   . GLY A 1 1093 ? 162.198 138.792 58.422  1.00 163.40 ? 1052 GLY A N   1 
ATOM   7350 C CA  . GLY A 1 1093 ? 161.638 139.321 57.162  1.00 163.40 ? 1052 GLY A CA  1 
ATOM   7351 C C   . GLY A 1 1093 ? 161.789 138.337 56.015  1.00 163.40 ? 1052 GLY A C   1 
ATOM   7352 O O   . GLY A 1 1093 ? 161.518 138.734 54.865  1.00 163.40 ? 1052 GLY A O   1 
ATOM   7353 N N   . LYS A 1 1094 ? 162.204 137.102 56.310  1.00 162.43 ? 1053 LYS A N   1 
ATOM   7354 C CA  . LYS A 1 1094 ? 162.423 136.085 55.245  1.00 162.43 ? 1053 LYS A CA  1 
ATOM   7355 C C   . LYS A 1 1094 ? 161.610 134.825 55.563  1.00 162.43 ? 1053 LYS A C   1 
ATOM   7356 O O   . LYS A 1 1094 ? 161.368 134.564 56.757  1.00 162.43 ? 1053 LYS A O   1 
ATOM   7357 C CB  . LYS A 1 1094 ? 163.914 135.764 55.111  1.00 162.43 ? 1053 LYS A CB  1 
ATOM   7358 C CG  . LYS A 1 1094 ? 164.779 136.916 54.620  1.00 162.43 ? 1053 LYS A CG  1 
ATOM   7359 C CD  . LYS A 1 1094 ? 166.231 136.537 54.440  1.00 162.43 ? 1053 LYS A CD  1 
ATOM   7360 C CE  . LYS A 1 1094 ? 166.422 135.327 53.551  1.00 162.43 ? 1053 LYS A CE  1 
ATOM   7361 N NZ  . LYS A 1 1094 ? 167.850 134.945 53.442  1.00 162.43 ? 1053 LYS A NZ  1 
ATOM   7362 N N   . THR A 1 1095 ? 161.214 134.078 54.529  1.00 158.19 ? 1054 THR A N   1 
ATOM   7363 C CA  . THR A 1 1095 ? 160.381 132.862 54.733  1.00 158.19 ? 1054 THR A CA  1 
ATOM   7364 C C   . THR A 1 1095 ? 161.282 131.626 54.808  1.00 158.19 ? 1054 THR A C   1 
ATOM   7365 O O   . THR A 1 1095 ? 162.083 131.425 53.873  1.00 158.19 ? 1054 THR A O   1 
ATOM   7366 C CB  . THR A 1 1095 ? 159.337 132.718 53.621  1.00 158.19 ? 1054 THR A CB  1 
ATOM   7367 O OG1 . THR A 1 1095 ? 160.022 132.396 52.410  1.00 158.19 ? 1054 THR A OG1 1 
ATOM   7368 C CG2 . THR A 1 1095 ? 158.508 133.969 53.427  1.00 158.19 ? 1054 THR A CG2 1 
ATOM   7369 N N   . LEU A 1 1096 ? 161.153 130.836 55.878  1.00 158.08 ? 1055 LEU A N   1 
ATOM   7370 C CA  . LEU A 1 1096 ? 161.943 129.581 56.007  1.00 158.08 ? 1055 LEU A CA  1 
ATOM   7371 C C   . LEU A 1 1096 ? 160.985 128.387 55.957  1.00 158.08 ? 1055 LEU A C   1 
ATOM   7372 O O   . LEU A 1 1096 ? 160.019 128.373 56.743  1.00 158.08 ? 1055 LEU A O   1 
ATOM   7373 C CB  . LEU A 1 1096 ? 162.720 129.604 57.326  1.00 158.08 ? 1055 LEU A CB  1 
ATOM   7374 C CG  . LEU A 1 1096 ? 163.314 128.264 57.756  1.00 158.08 ? 1055 LEU A CG  1 
ATOM   7375 C CD1 . LEU A 1 1096 ? 164.476 127.870 56.857  1.00 158.08 ? 1055 LEU A CD1 1 
ATOM   7376 C CD2 . LEU A 1 1096 ? 163.756 128.304 59.211  1.00 158.08 ? 1055 LEU A CD2 1 
ATOM   7377 N N   . ALA A 1 1097 ? 161.248 127.429 55.065  1.00 160.25 ? 1056 ALA A N   1 
ATOM   7378 C CA  . ALA A 1 1097 ? 160.394 126.224 54.966  1.00 160.25 ? 1056 ALA A CA  1 
ATOM   7379 C C   . ALA A 1 1097 ? 161.152 125.017 55.525  1.00 160.25 ? 1056 ALA A C   1 
ATOM   7380 O O   . ALA A 1 1097 ? 162.308 124.797 55.108  1.00 160.25 ? 1056 ALA A O   1 
ATOM   7381 C CB  . ALA A 1 1097 ? 159.978 126.004 53.534  1.00 160.25 ? 1056 ALA A CB  1 
ATOM   7382 N N   . LEU A 1 1098 ? 160.524 124.272 56.438  1.00 160.22 ? 1057 LEU A N   1 
ATOM   7383 C CA  . LEU A 1 1098 ? 161.172 123.076 57.037  1.00 160.22 ? 1057 LEU A CA  1 
ATOM   7384 C C   . LEU A 1 1098 ? 160.717 121.829 56.272  1.00 160.22 ? 1057 LEU A C   1 
ATOM   7385 O O   . LEU A 1 1098 ? 159.498 121.579 56.226  1.00 160.22 ? 1057 LEU A O   1 
ATOM   7386 C CB  . LEU A 1 1098 ? 160.784 122.986 58.515  1.00 160.22 ? 1057 LEU A CB  1 
ATOM   7387 C CG  . LEU A 1 1098 ? 161.263 124.144 59.389  1.00 160.22 ? 1057 LEU A CG  1 
ATOM   7388 C CD1 . LEU A 1 1098 ? 161.146 123.792 60.864  1.00 160.22 ? 1057 LEU A CD1 1 
ATOM   7389 C CD2 . LEU A 1 1098 ? 162.695 124.523 59.045  1.00 160.22 ? 1057 LEU A CD2 1 
ATOM   7390 N N   . VAL A 1 1099 ? 161.667 121.088 55.695  1.00 167.51 ? 1058 VAL A N   1 
ATOM   7391 C CA  . VAL A 1 1099 ? 161.327 119.839 54.952  1.00 167.51 ? 1058 VAL A CA  1 
ATOM   7392 C C   . VAL A 1 1099 ? 162.133 118.686 55.560  1.00 167.51 ? 1058 VAL A C   1 
ATOM   7393 O O   . VAL A 1 1099 ? 163.238 118.945 56.080  1.00 167.51 ? 1058 VAL A O   1 
ATOM   7394 C CB  . VAL A 1 1099 ? 161.589 119.992 53.441  1.00 167.51 ? 1058 VAL A CB  1 
ATOM   7395 C CG1 . VAL A 1 1099 ? 163.074 120.032 53.117  1.00 167.51 ? 1058 VAL A CG1 1 
ATOM   7396 C CG2 . VAL A 1 1099 ? 160.892 118.910 52.630  1.00 167.51 ? 1058 VAL A CG2 1 
ATOM   7397 N N   . GLY A 1 1100 ? 161.585 117.468 55.523  1.00 169.08 ? 1059 GLY A N   1 
ATOM   7398 C CA  . GLY A 1 1100 ? 162.285 116.299 56.089  1.00 169.08 ? 1059 GLY A CA  1 
ATOM   7399 C C   . GLY A 1 1100 ? 161.319 115.185 56.451  1.00 169.08 ? 1059 GLY A C   1 
ATOM   7400 O O   . GLY A 1 1100 ? 160.121 115.312 56.127  1.00 169.08 ? 1059 GLY A O   1 
ATOM   7401 N N   . PRO A 1 1101 ? 161.753 114.094 57.131  1.00 173.82 ? 1060 PRO A N   1 
ATOM   7402 C CA  . PRO A 1 1101 ? 160.863 112.972 57.436  1.00 173.82 ? 1060 PRO A CA  1 
ATOM   7403 C C   . PRO A 1 1101 ? 159.757 113.404 58.409  1.00 173.82 ? 1060 PRO A C   1 
ATOM   7404 O O   . PRO A 1 1101 ? 160.032 114.205 59.285  1.00 173.82 ? 1060 PRO A O   1 
ATOM   7405 C CB  . PRO A 1 1101 ? 161.759 111.933 58.128  1.00 173.82 ? 1060 PRO A CB  1 
ATOM   7406 C CG  . PRO A 1 1101 ? 163.165 112.338 57.754  1.00 173.82 ? 1060 PRO A CG  1 
ATOM   7407 C CD  . PRO A 1 1101 ? 163.107 113.846 57.654  1.00 173.82 ? 1060 PRO A CD  1 
ATOM   7408 N N   . SER A 1 1102 ? 158.551 112.855 58.242  1.00 177.68 ? 1061 SER A N   1 
ATOM   7409 C CA  . SER A 1 1102 ? 157.419 113.195 59.145  1.00 177.68 ? 1061 SER A CA  1 
ATOM   7410 C C   . SER A 1 1102 ? 157.775 112.812 60.585  1.00 177.68 ? 1061 SER A C   1 
ATOM   7411 O O   . SER A 1 1102 ? 157.312 113.509 61.510  1.00 177.68 ? 1061 SER A O   1 
ATOM   7412 C CB  . SER A 1 1102 ? 156.150 112.518 58.696  1.00 177.68 ? 1061 SER A CB  1 
ATOM   7413 O OG  . SER A 1 1102 ? 155.083 112.813 59.584  1.00 177.68 ? 1061 SER A OG  1 
ATOM   7414 N N   . GLY A 1 1103 ? 158.565 111.749 60.762  1.00 178.35 ? 1062 GLY A N   1 
ATOM   7415 C CA  . GLY A 1 1103 ? 158.954 111.298 62.112  1.00 178.35 ? 1062 GLY A CA  1 
ATOM   7416 C C   . GLY A 1 1103 ? 159.660 112.397 62.886  1.00 178.35 ? 1062 GLY A C   1 
ATOM   7417 O O   . GLY A 1 1103 ? 159.346 112.570 64.079  1.00 178.35 ? 1062 GLY A O   1 
ATOM   7418 N N   . CYS A 1 1104 ? 160.576 113.120 62.232  1.00 172.69 ? 1063 CYS A N   1 
ATOM   7419 C CA  . CYS A 1 1104 ? 161.286 114.247 62.896  1.00 172.69 ? 1063 CYS A CA  1 
ATOM   7420 C C   . CYS A 1 1104 ? 160.271 115.335 63.262  1.00 172.69 ? 1063 CYS A C   1 
ATOM   7421 O O   . CYS A 1 1104 ? 159.345 115.568 62.459  1.00 172.69 ? 1063 CYS A O   1 
ATOM   7422 C CB  . CYS A 1 1104 ? 162.363 114.822 61.985  1.00 172.69 ? 1063 CYS A CB  1 
ATOM   7423 S SG  . CYS A 1 1104 ? 163.665 113.635 61.567  1.00 172.69 ? 1063 CYS A SG  1 
ATOM   7424 N N   . GLY A 1 1105 ? 160.446 115.982 64.418  1.00 166.04 ? 1064 GLY A N   1 
ATOM   7425 C CA  . GLY A 1 1105 ? 159.466 116.985 64.881  1.00 166.04 ? 1064 GLY A CA  1 
ATOM   7426 C C   . GLY A 1 1105 ? 159.675 118.350 64.248  1.00 166.04 ? 1064 GLY A C   1 
ATOM   7427 O O   . GLY A 1 1105 ? 160.130 119.262 64.963  1.00 166.04 ? 1064 GLY A O   1 
ATOM   7428 N N   . LYS A 1 1106 ? 159.351 118.494 62.959  1.00 158.85 ? 1065 LYS A N   1 
ATOM   7429 C CA  . LYS A 1 1106 ? 159.434 119.830 62.309  1.00 158.85 ? 1065 LYS A CA  1 
ATOM   7430 C C   . LYS A 1 1106 ? 158.394 120.747 62.961  1.00 158.85 ? 1065 LYS A C   1 
ATOM   7431 O O   . LYS A 1 1106 ? 158.706 121.934 63.173  1.00 158.85 ? 1065 LYS A O   1 
ATOM   7432 C CB  . LYS A 1 1106 ? 159.196 119.713 60.800  1.00 158.85 ? 1065 LYS A CB  1 
ATOM   7433 C CG  . LYS A 1 1106 ? 160.313 119.037 60.019  1.00 158.85 ? 1065 LYS A CG  1 
ATOM   7434 C CD  . LYS A 1 1106 ? 160.056 118.977 58.530  1.00 158.85 ? 1065 LYS A CD  1 
ATOM   7435 C CE  . LYS A 1 1106 ? 158.871 118.108 58.168  1.00 158.85 ? 1065 LYS A CE  1 
ATOM   7436 N NZ  . LYS A 1 1106 ? 159.065 116.707 58.611  1.00 158.85 ? 1065 LYS A NZ  1 
ATOM   7437 N N   . SER A 1 1107 ? 157.208 120.211 63.260  1.00 148.87 ? 1066 SER A N   1 
ATOM   7438 C CA  . SER A 1 1107 ? 156.150 121.006 63.938  1.00 148.87 ? 1066 SER A CA  1 
ATOM   7439 C C   . SER A 1 1107 ? 156.594 121.346 65.364  1.00 148.87 ? 1066 SER A C   1 
ATOM   7440 O O   . SER A 1 1107 ? 156.235 122.431 65.851  1.00 148.87 ? 1066 SER A O   1 
ATOM   7441 C CB  . SER A 1 1107 ? 154.839 120.270 63.934  1.00 148.87 ? 1066 SER A CB  1 
ATOM   7442 O OG  . SER A 1 1107 ? 154.955 119.036 64.630  1.00 148.87 ? 1066 SER A OG  1 
ATOM   7443 N N   . SER A 1 1108 ? 157.354 120.450 66.002  1.00 145.85 ? 1067 SER A N   1 
ATOM   7444 C CA  . SER A 1 1108 ? 157.800 120.675 67.403  1.00 145.85 ? 1067 SER A CA  1 
ATOM   7445 C C   . SER A 1 1108 ? 158.627 121.962 67.485  1.00 145.85 ? 1067 SER A C   1 
ATOM   7446 O O   . SER A 1 1108 ? 158.687 122.553 68.580  1.00 145.85 ? 1067 SER A O   1 
ATOM   7447 C CB  . SER A 1 1108 ? 158.575 119.493 67.921  1.00 145.85 ? 1067 SER A CB  1 
ATOM   7448 O OG  . SER A 1 1108 ? 157.798 118.307 67.846  1.00 145.85 ? 1067 SER A OG  1 
ATOM   7449 N N   . VAL A 1 1109 ? 159.226 122.379 66.367  1.00 144.26 ? 1068 VAL A N   1 
ATOM   7450 C CA  . VAL A 1 1109 ? 160.008 123.651 66.342  1.00 144.26 ? 1068 VAL A CA  1 
ATOM   7451 C C   . VAL A 1 1109 ? 159.078 124.799 66.744  1.00 144.26 ? 1068 VAL A C   1 
ATOM   7452 O O   . VAL A 1 1109 ? 159.474 125.602 67.609  1.00 144.26 ? 1068 VAL A O   1 
ATOM   7453 C CB  . VAL A 1 1109 ? 160.636 123.896 64.957  1.00 144.26 ? 1068 VAL A CB  1 
ATOM   7454 C CG1 . VAL A 1 1109 ? 161.359 125.232 64.891  1.00 144.26 ? 1068 VAL A CG1 1 
ATOM   7455 C CG2 . VAL A 1 1109 ? 161.563 122.762 64.551  1.00 144.26 ? 1068 VAL A CG2 1 
ATOM   7456 N N   . ILE A 1 1110 ? 157.884 124.860 66.146  1.00 138.98 ? 1069 ILE A N   1 
ATOM   7457 C CA  . ILE A 1 1110 ? 156.930 125.972 66.438  1.00 138.98 ? 1069 ILE A CA  1 
ATOM   7458 C C   . ILE A 1 1110 ? 156.510 125.889 67.911  1.00 138.98 ? 1069 ILE A C   1 
ATOM   7459 O O   . ILE A 1 1110 ? 156.279 126.955 68.511  1.00 138.98 ? 1069 ILE A O   1 
ATOM   7460 C CB  . ILE A 1 1110 ? 155.723 125.942 65.475  1.00 138.98 ? 1069 ILE A CB  1 
ATOM   7461 C CG1 . ILE A 1 1110 ? 154.578 125.070 65.996  1.00 138.98 ? 1069 ILE A CG1 1 
ATOM   7462 C CG2 . ILE A 1 1110 ? 156.161 125.526 64.079  1.00 138.98 ? 1069 ILE A CG2 1 
ATOM   7463 C CD1 . ILE A 1 1110 ? 153.452 124.885 65.008  1.00 138.98 ? 1069 ILE A CD1 1 
ATOM   7464 N N   . SER A 1 1111 ? 156.428 124.676 68.469  1.00 133.55 ? 1070 SER A N   1 
ATOM   7465 C CA  . SER A 1 1111 ? 156.086 124.513 69.907  1.00 133.55 ? 1070 SER A CA  1 
ATOM   7466 C C   . SER A 1 1111 ? 157.170 125.178 70.759  1.00 133.55 ? 1070 SER A C   1 
ATOM   7467 O O   . SER A 1 1111 ? 156.816 125.866 71.736  1.00 133.55 ? 1070 SER A O   1 
ATOM   7468 C CB  . SER A 1 1111 ? 155.918 123.060 70.263  1.00 133.55 ? 1070 SER A CB  1 
ATOM   7469 O OG  . SER A 1 1111 ? 154.928 122.453 69.445  1.00 133.55 ? 1070 SER A OG  1 
ATOM   7470 N N   . LEU A 1 1112 ? 158.440 124.984 70.392  1.00 138.16 ? 1071 LEU A N   1 
ATOM   7471 C CA  . LEU A 1 1112 ? 159.558 125.635 71.126  1.00 138.16 ? 1071 LEU A CA  1 
ATOM   7472 C C   . LEU A 1 1112 ? 159.430 127.154 70.972  1.00 138.16 ? 1071 LEU A C   1 
ATOM   7473 O O   . LEU A 1 1112 ? 159.716 127.870 71.951  1.00 138.16 ? 1071 LEU A O   1 
ATOM   7474 C CB  . LEU A 1 1112 ? 160.885 125.134 70.549  1.00 138.16 ? 1071 LEU A CB  1 
ATOM   7475 C CG  . LEU A 1 1112 ? 161.072 123.617 70.546  1.00 138.16 ? 1071 LEU A CG  1 
ATOM   7476 C CD1 . LEU A 1 1112 ? 162.465 123.244 70.063  1.00 138.16 ? 1071 LEU A CD1 1 
ATOM   7477 C CD2 . LEU A 1 1112 ? 160.814 123.035 71.925  1.00 138.16 ? 1071 LEU A CD2 1 
ATOM   7478 N N   . ILE A 1 1113 ? 159.015 127.619 69.789  1.00 136.53 ? 1072 ILE A N   1 
ATOM   7479 C CA  . ILE A 1 1113 ? 158.873 129.084 69.533  1.00 136.53 ? 1072 ILE A CA  1 
ATOM   7480 C C   . ILE A 1 1113 ? 157.837 129.662 70.505  1.00 136.53 ? 1072 ILE A C   1 
ATOM   7481 O O   . ILE A 1 1113 ? 158.126 130.710 71.116  1.00 136.53 ? 1072 ILE A O   1 
ATOM   7482 C CB  . ILE A 1 1113 ? 158.486 129.352 68.065  1.00 136.53 ? 1072 ILE A CB  1 
ATOM   7483 C CG1 . ILE A 1 1113 ? 159.488 128.731 67.089  1.00 136.53 ? 1072 ILE A CG1 1 
ATOM   7484 C CG2 . ILE A 1 1113 ? 158.309 130.842 67.815  1.00 136.53 ? 1072 ILE A CG2 1 
ATOM   7485 C CD1 . ILE A 1 1113 ? 160.903 129.226 67.268  1.00 136.53 ? 1072 ILE A CD1 1 
ATOM   7486 N N   . GLN A 1 1114 ? 156.689 128.994 70.653  1.00 129.93 ? 1073 GLN A N   1 
ATOM   7487 C CA  . GLN A 1 1114 ? 155.620 129.484 71.568  1.00 129.93 ? 1073 GLN A CA  1 
ATOM   7488 C C   . GLN A 1 1114 ? 155.938 129.028 72.996  1.00 129.93 ? 1073 GLN A C   1 
ATOM   7489 O O   . GLN A 1 1114 ? 155.095 129.264 73.885  1.00 129.93 ? 1073 GLN A O   1 
ATOM   7490 C CB  . GLN A 1 1114 ? 154.248 128.993 71.102  1.00 129.93 ? 1073 GLN A CB  1 
ATOM   7491 C CG  . GLN A 1 1114 ? 154.213 127.513 70.762  1.00 129.93 ? 1073 GLN A CG  1 
ATOM   7492 C CD  . GLN A 1 1114 ? 152.971 127.143 69.992  1.00 129.93 ? 1073 GLN A CD  1 
ATOM   7493 O OE1 . GLN A 1 1114 ? 152.073 127.959 69.797  1.00 129.93 ? 1073 GLN A OE1 1 
ATOM   7494 N NE2 . GLN A 1 1114 ? 152.906 125.896 69.555  1.00 129.93 ? 1073 GLN A NE2 1 
ATOM   7495 N N   . ARG A 1 1115 ? 157.091 128.385 73.196  1.00 131.69 ? 1074 ARG A N   1 
ATOM   7496 C CA  . ARG A 1 1115 ? 157.526 127.950 74.552  1.00 131.69 ? 1074 ARG A CA  1 
ATOM   7497 C C   . ARG A 1 1115 ? 156.499 126.992 75.164  1.00 131.69 ? 1074 ARG A C   1 
ATOM   7498 O O   . ARG A 1 1115 ? 156.374 126.989 76.404  1.00 131.69 ? 1074 ARG A O   1 
ATOM   7499 C CB  . ARG A 1 1115 ? 157.765 129.160 75.462  1.00 131.69 ? 1074 ARG A CB  1 
ATOM   7500 C CG  . ARG A 1 1115 ? 159.008 129.965 75.109  1.00 131.69 ? 1074 ARG A CG  1 
ATOM   7501 C CD  . ARG A 1 1115 ? 159.484 130.782 76.292  1.00 131.69 ? 1074 ARG A CD  1 
ATOM   7502 N NE  . ARG A 1 1115 ? 159.706 129.939 77.457  1.00 131.69 ? 1074 ARG A NE  1 
ATOM   7503 C CZ  . ARG A 1 1115 ? 160.128 130.379 78.637  1.00 131.69 ? 1074 ARG A CZ  1 
ATOM   7504 N NH1 . ARG A 1 1115 ? 160.159 129.562 79.674  1.00 131.69 ? 1074 ARG A NH1 1 
ATOM   7505 N NH2 . ARG A 1 1115 ? 160.516 131.636 78.775  1.00 131.69 ? 1074 ARG A NH2 1 
ATOM   7506 N N   . PHE A 1 1116 ? 155.792 126.213 74.339  1.00 120.54 ? 1075 PHE A N   1 
ATOM   7507 C CA  . PHE A 1 1116 ? 154.878 125.188 74.906  1.00 120.54 ? 1075 PHE A CA  1 
ATOM   7508 C C   . PHE A 1 1116 ? 155.742 124.171 75.651  1.00 120.54 ? 1075 PHE A C   1 
ATOM   7509 O O   . PHE A 1 1116 ? 155.355 123.748 76.758  1.00 120.54 ? 1075 PHE A O   1 
ATOM   7510 C CB  . PHE A 1 1116 ? 154.045 124.526 73.806  1.00 120.54 ? 1075 PHE A CB  1 
ATOM   7511 C CG  . PHE A 1 1116 ? 152.813 125.301 73.417  1.00 120.54 ? 1075 PHE A CG  1 
ATOM   7512 C CD1 . PHE A 1 1116 ? 152.536 126.526 74.002  1.00 120.54 ? 1075 PHE A CD1 1 
ATOM   7513 C CD2 . PHE A 1 1116 ? 151.923 124.799 72.483  1.00 120.54 ? 1075 PHE A CD2 1 
ATOM   7514 C CE1 . PHE A 1 1116 ? 151.401 127.238 73.651  1.00 120.54 ? 1075 PHE A CE1 1 
ATOM   7515 C CE2 . PHE A 1 1116 ? 150.788 125.512 72.133  1.00 120.54 ? 1075 PHE A CE2 1 
ATOM   7516 C CZ  . PHE A 1 1116 ? 150.531 126.731 72.717  1.00 120.54 ? 1075 PHE A CZ  1 
ATOM   7517 N N   . TYR A 1 1117 ? 156.882 123.804 75.058  1.00 132.40 ? 1076 TYR A N   1 
ATOM   7518 C CA  . TYR A 1 1117 ? 157.831 122.873 75.719  1.00 132.40 ? 1076 TYR A CA  1 
ATOM   7519 C C   . TYR A 1 1117 ? 159.221 123.511 75.666  1.00 132.40 ? 1076 TYR A C   1 
ATOM   7520 O O   . TYR A 1 1117 ? 159.522 124.204 74.675  1.00 132.40 ? 1076 TYR A O   1 
ATOM   7521 C CB  . TYR A 1 1117 ? 157.817 121.513 75.020  1.00 132.40 ? 1076 TYR A CB  1 
ATOM   7522 C CG  . TYR A 1 1117 ? 156.440 120.961 74.750  1.00 132.40 ? 1076 TYR A CG  1 
ATOM   7523 C CD1 . TYR A 1 1117 ? 155.570 120.668 75.786  1.00 132.40 ? 1076 TYR A CD1 1 
ATOM   7524 C CD2 . TYR A 1 1117 ? 156.001 120.744 73.454  1.00 132.40 ? 1076 TYR A CD2 1 
ATOM   7525 C CE1 . TYR A 1 1117 ? 154.302 120.166 75.545  1.00 132.40 ? 1076 TYR A CE1 1 
ATOM   7526 C CE2 . TYR A 1 1117 ? 154.736 120.244 73.195  1.00 132.40 ? 1076 TYR A CE2 1 
ATOM   7527 C CZ  . TYR A 1 1117 ? 153.884 119.954 74.244  1.00 132.40 ? 1076 TYR A CZ  1 
ATOM   7528 O OH  . TYR A 1 1117 ? 152.628 119.455 73.994  1.00 132.40 ? 1076 TYR A OH  1 
ATOM   7529 N N   . GLU A 1 1118 ? 160.031 123.302 76.706  1.00 139.92 ? 1077 GLU A N   1 
ATOM   7530 C CA  . GLU A 1 1118 ? 161.390 123.902 76.746  1.00 139.92 ? 1077 GLU A CA  1 
ATOM   7531 C C   . GLU A 1 1118 ? 162.408 122.861 76.268  1.00 139.92 ? 1077 GLU A C   1 
ATOM   7532 O O   . GLU A 1 1118 ? 162.355 121.715 76.753  1.00 139.92 ? 1077 GLU A O   1 
ATOM   7533 C CB  . GLU A 1 1118 ? 161.711 124.415 78.152  1.00 139.92 ? 1077 GLU A CB  1 
ATOM   7534 C CG  . GLU A 1 1118 ? 160.708 125.436 78.658  1.00 139.92 ? 1077 GLU A CG  1 
ATOM   7535 C CD  . GLU A 1 1118 ? 160.358 126.533 77.667  1.00 139.92 ? 1077 GLU A CD  1 
ATOM   7536 O OE1 . GLU A 1 1118 ? 159.174 126.634 77.298  1.00 139.92 ? 1077 GLU A OE1 1 
ATOM   7537 O OE2 . GLU A 1 1118 ? 161.268 127.285 77.270  1.00 139.92 ? 1077 GLU A OE2 1 
ATOM   7538 N N   . PRO A 1 1119 ? 163.322 123.208 75.335  1.00 146.84 ? 1078 PRO A N   1 
ATOM   7539 C CA  . PRO A 1 1119 ? 164.282 122.243 74.798  1.00 146.84 ? 1078 PRO A CA  1 
ATOM   7540 C C   . PRO A 1 1119 ? 165.139 121.643 75.920  1.00 146.84 ? 1078 PRO A C   1 
ATOM   7541 O O   . PRO A 1 1119 ? 165.620 122.394 76.750  1.00 146.84 ? 1078 PRO A O   1 
ATOM   7542 C CB  . PRO A 1 1119 ? 165.161 123.073 73.850  1.00 146.84 ? 1078 PRO A CB  1 
ATOM   7543 C CG  . PRO A 1 1119 ? 164.918 124.512 74.260  1.00 146.84 ? 1078 PRO A CG  1 
ATOM   7544 C CD  . PRO A 1 1119 ? 163.489 124.542 74.759  1.00 146.84 ? 1078 PRO A CD  1 
ATOM   7545 N N   . SER A 1 1120 ? 165.301 120.318 75.917  1.00 153.43 ? 1079 SER A N   1 
ATOM   7546 C CA  . SER A 1 1120 ? 166.127 119.641 76.953  1.00 153.43 ? 1079 SER A CA  1 
ATOM   7547 C C   . SER A 1 1120 ? 167.383 120.473 77.226  1.00 153.43 ? 1079 SER A C   1 
ATOM   7548 O O   . SER A 1 1120 ? 167.817 120.513 78.393  1.00 153.43 ? 1079 SER A O   1 
ATOM   7549 C CB  . SER A 1 1120 ? 166.476 118.241 76.528  1.00 153.43 ? 1079 SER A CB  1 
ATOM   7550 O OG  . SER A 1 1120 ? 165.307 117.517 76.178  1.00 153.43 ? 1079 SER A OG  1 
ATOM   7551 N N   . SER A 1 1121 ? 167.934 121.115 76.189  1.00 159.76 ? 1080 SER A N   1 
ATOM   7552 C CA  . SER A 1 1121 ? 169.139 121.915 76.354  1.00 159.76 ? 1080 SER A CA  1 
ATOM   7553 C C   . SER A 1 1121 ? 169.294 122.822 75.144  1.00 159.76 ? 1080 SER A C   1 
ATOM   7554 O O   . SER A 1 1121 ? 168.726 122.571 74.079  1.00 159.76 ? 1080 SER A O   1 
ATOM   7555 C CB  . SER A 1 1121 ? 170.381 121.036 76.531  1.00 159.76 ? 1080 SER A CB  1 
ATOM   7556 O OG  . SER A 1 1121 ? 171.553 121.828 76.624  1.00 159.76 ? 1080 SER A OG  1 
ATOM   7557 N N   . GLY A 1 1122 ? 170.078 123.877 75.322  1.00 162.37 ? 1081 GLY A N   1 
ATOM   7558 C CA  . GLY A 1 1122 ? 170.310 124.838 74.267  1.00 162.37 ? 1081 GLY A CA  1 
ATOM   7559 C C   . GLY A 1 1122 ? 169.564 126.142 74.499  1.00 162.37 ? 1081 GLY A C   1 
ATOM   7560 O O   . GLY A 1 1122 ? 168.630 126.233 75.299  1.00 162.37 ? 1081 GLY A O   1 
ATOM   7561 N N   . ARG A 1 1123 ? 169.989 127.172 73.771  1.00 164.90 ? 1082 ARG A N   1 
ATOM   7562 C CA  . ARG A 1 1123 ? 169.445 128.514 73.914  1.00 164.90 ? 1082 ARG A CA  1 
ATOM   7563 C C   . ARG A 1 1123 ? 168.913 128.999 72.574  1.00 164.90 ? 1082 ARG A C   1 
ATOM   7564 O O   . ARG A 1 1123 ? 169.548 128.800 71.535  1.00 164.90 ? 1082 ARG A O   1 
ATOM   7565 C CB  . ARG A 1 1123 ? 170.514 129.474 74.471  1.00 164.90 ? 1082 ARG A CB  1 
ATOM   7566 C CG  . ARG A 1 1123 ? 170.113 130.939 74.525  1.00 164.90 ? 1082 ARG A CG  1 
ATOM   7567 C CD  . ARG A 1 1123 ? 171.188 131.850 73.932  1.00 164.90 ? 1082 ARG A CD  1 
ATOM   7568 N NE  . ARG A 1 1123 ? 171.807 131.324 72.722  1.00 164.90 ? 1082 ARG A NE  1 
ATOM   7569 C CZ  . ARG A 1 1123 ? 171.211 131.253 71.540  1.00 164.90 ? 1082 ARG A CZ  1 
ATOM   7570 N NH1 . ARG A 1 1123 ? 169.978 131.695 71.359  1.00 164.90 ? 1082 ARG A NH1 1 
ATOM   7571 N NH2 . ARG A 1 1123 ? 171.874 130.735 70.510  1.00 164.90 ? 1082 ARG A NH2 1 
ATOM   7572 N N   . VAL A 1 1124 ? 167.735 129.618 72.605  1.00 165.60 ? 1083 VAL A N   1 
ATOM   7573 C CA  . VAL A 1 1124 ? 167.070 130.137 71.415  1.00 165.60 ? 1083 VAL A CA  1 
ATOM   7574 C C   . VAL A 1 1124 ? 166.835 131.631 71.597  1.00 165.60 ? 1083 VAL A C   1 
ATOM   7575 O O   . VAL A 1 1124 ? 166.437 132.084 72.676  1.00 165.60 ? 1083 VAL A O   1 
ATOM   7576 C CB  . VAL A 1 1124 ? 165.752 129.384 71.120  1.00 165.60 ? 1083 VAL A CB  1 
ATOM   7577 C CG1 . VAL A 1 1124 ? 164.743 129.581 72.234  1.00 165.60 ? 1083 VAL A CG1 1 
ATOM   7578 C CG2 . VAL A 1 1124 ? 165.171 129.836 69.790  1.00 165.60 ? 1083 VAL A CG2 1 
ATOM   7579 N N   . MET A 1 1125 ? 167.114 132.395 70.545  1.00 164.93 ? 1084 MET A N   1 
ATOM   7580 C CA  . MET A 1 1125 ? 167.100 133.848 70.590  1.00 164.93 ? 1084 MET A CA  1 
ATOM   7581 C C   . MET A 1 1125 ? 166.042 134.390 69.637  1.00 164.93 ? 1084 MET A C   1 
ATOM   7582 O O   . MET A 1 1125 ? 165.757 133.792 68.596  1.00 164.93 ? 1084 MET A O   1 
ATOM   7583 C CB  . MET A 1 1125 ? 168.494 134.408 70.242  1.00 164.93 ? 1084 MET A CB  1 
ATOM   7584 C CG  . MET A 1 1125 ? 168.649 135.921 70.311  1.00 164.93 ? 1084 MET A CG  1 
ATOM   7585 S SD  . MET A 1 1125 ? 168.061 136.770 68.834  1.00 164.93 ? 1084 MET A SD  1 
ATOM   7586 C CE  . MET A 1 1125 ? 169.343 136.331 67.664  1.00 164.93 ? 1084 MET A CE  1 
ATOM   7587 N N   . ILE A 1 1126 ? 165.461 135.531 70.004  1.00 164.75 ? 1085 ILE A N   1 
ATOM   7588 C CA  . ILE A 1 1126 ? 164.408 136.177 69.226  1.00 164.75 ? 1085 ILE A CA  1 
ATOM   7589 C C   . ILE A 1 1126 ? 164.839 137.620 68.988  1.00 164.75 ? 1085 ILE A C   1 
ATOM   7590 O O   . ILE A 1 1126 ? 164.619 138.487 69.842  1.00 164.75 ? 1085 ILE A O   1 
ATOM   7591 C CB  . ILE A 1 1126 ? 163.047 136.120 69.924  1.00 164.75 ? 1085 ILE A CB  1 
ATOM   7592 C CG1 . ILE A 1 1126 ? 162.633 134.671 70.178  1.00 164.75 ? 1085 ILE A CG1 1 
ATOM   7593 C CG2 . ILE A 1 1126 ? 161.991 136.810 69.079  1.00 164.75 ? 1085 ILE A CG2 1 
ATOM   7594 C CD1 . ILE A 1 1126 ? 162.484 133.857 68.926  1.00 164.75 ? 1085 ILE A CD1 1 
ATOM   7595 N N   . ASP A 1 1127 ? 165.457 137.880 67.835  1.00 168.30 ? 1086 ASP A N   1 
ATOM   7596 C CA  . ASP A 1 1127 ? 165.783 139.233 67.380  1.00 168.30 ? 1086 ASP A CA  1 
ATOM   7597 C C   . ASP A 1 1127 ? 166.641 139.982 68.403  1.00 168.30 ? 1086 ASP A C   1 
ATOM   7598 O O   . ASP A 1 1127 ? 166.240 141.004 68.965  1.00 168.30 ? 1086 ASP A O   1 
ATOM   7599 C CB  . ASP A 1 1127 ? 164.507 140.015 67.053  1.00 168.30 ? 1086 ASP A CB  1 
ATOM   7600 C CG  . ASP A 1 1127 ? 164.758 141.170 66.103  1.00 168.30 ? 1086 ASP A CG  1 
ATOM   7601 O OD1 . ASP A 1 1127 ? 165.918 141.352 65.677  1.00 168.30 ? 1086 ASP A OD1 1 
ATOM   7602 O OD2 . ASP A 1 1127 ? 163.796 141.899 65.787  1.00 168.30 ? 1086 ASP A OD2 1 
ATOM   7603 N N   . GLY A 1 1128 ? 167.838 139.453 68.637  1.00 167.58 ? 1087 GLY A N   1 
ATOM   7604 C CA  . GLY A 1 1128 ? 168.781 140.111 69.520  1.00 167.58 ? 1087 GLY A CA  1 
ATOM   7605 C C   . GLY A 1 1128 ? 168.516 139.933 70.995  1.00 167.58 ? 1087 GLY A C   1 
ATOM   7606 O O   . GLY A 1 1128 ? 169.244 140.504 71.812  1.00 167.58 ? 1087 GLY A O   1 
ATOM   7607 N N   . LYS A 1 1129 ? 167.498 139.162 71.366  1.00 164.63 ? 1088 LYS A N   1 
ATOM   7608 C CA  . LYS A 1 1129 ? 167.171 138.922 72.765  1.00 164.63 ? 1088 LYS A CA  1 
ATOM   7609 C C   . LYS A 1 1129 ? 166.726 137.480 72.930  1.00 164.63 ? 1088 LYS A C   1 
ATOM   7610 O O   . LYS A 1 1129 ? 165.912 136.987 72.143  1.00 164.63 ? 1088 LYS A O   1 
ATOM   7611 C CB  . LYS A 1 1129 ? 166.070 139.871 73.252  1.00 164.63 ? 1088 LYS A CB  1 
ATOM   7612 C CG  . LYS A 1 1129 ? 166.545 141.278 73.565  1.00 164.63 ? 1088 LYS A CG  1 
ATOM   7613 C CD  . LYS A 1 1129 ? 165.386 142.161 74.001  1.00 164.63 ? 1088 LYS A CD  1 
ATOM   7614 C CE  . LYS A 1 1129 ? 165.875 143.494 74.540  1.00 164.63 ? 1088 LYS A CE  1 
ATOM   7615 N NZ  . LYS A 1 1129 ? 166.686 143.325 75.776  1.00 164.63 ? 1088 LYS A NZ  1 
ATOM   7616 N N   . ASP A 1 1130 ? 167.263 136.810 73.944  1.00 159.10 ? 1089 ASP A N   1 
ATOM   7617 C CA  . ASP A 1 1130 ? 166.848 135.447 74.236  1.00 159.10 ? 1089 ASP A CA  1 
ATOM   7618 C C   . ASP A 1 1130 ? 165.406 135.473 74.726  1.00 159.10 ? 1089 ASP A C   1 
ATOM   7619 O O   . ASP A 1 1130 ? 164.991 136.393 75.435  1.00 159.10 ? 1089 ASP A O   1 
ATOM   7620 C CB  . ASP A 1 1130 ? 167.786 134.829 75.283  1.00 159.10 ? 1089 ASP A CB  1 
ATOM   7621 C CG  . ASP A 1 1130 ? 167.310 133.474 75.821  1.00 159.10 ? 1089 ASP A CG  1 
ATOM   7622 O OD1 . ASP A 1 1130 ? 166.115 133.127 75.755  1.00 159.10 ? 1089 ASP A OD1 1 
ATOM   7623 O OD2 . ASP A 1 1130 ? 168.179 132.718 76.301  1.00 159.10 ? 1089 ASP A OD2 1 
ATOM   7624 N N   . ILE A 1 1131 ? 164.637 134.452 74.341  1.00 153.11 ? 1090 ILE A N   1 
ATOM   7625 C CA  . ILE A 1 1131 ? 163.233 134.405 74.729  1.00 153.11 ? 1090 ILE A CA  1 
ATOM   7626 C C   . ILE A 1 1131 ? 163.056 133.979 76.182  1.00 153.11 ? 1090 ILE A C   1 
ATOM   7627 O O   . ILE A 1 1131 ? 162.025 134.292 76.790  1.00 153.11 ? 1090 ILE A O   1 
ATOM   7628 C CB  . ILE A 1 1131 ? 162.449 133.469 73.792  1.00 153.11 ? 1090 ILE A CB  1 
ATOM   7629 C CG1 . ILE A 1 1131 ? 160.943 133.608 74.016  1.00 153.11 ? 1090 ILE A CG1 1 
ATOM   7630 C CG2 . ILE A 1 1131 ? 162.862 132.031 74.013  1.00 153.11 ? 1090 ILE A CG2 1 
ATOM   7631 C CD1 . ILE A 1 1131 ? 160.107 132.972 72.931  1.00 153.11 ? 1090 ILE A CD1 1 
ATOM   7632 N N   . ARG A 1 1132 ? 164.039 133.286 76.762  1.00 149.21 ? 1091 ARG A N   1 
ATOM   7633 C CA  . ARG A 1 1132 ? 163.902 132.812 78.136  1.00 149.21 ? 1091 ARG A CA  1 
ATOM   7634 C C   . ARG A 1 1132 ? 163.735 133.977 79.101  1.00 149.21 ? 1091 ARG A C   1 
ATOM   7635 O O   . ARG A 1 1132 ? 162.788 134.012 79.896  1.00 149.21 ? 1091 ARG A O   1 
ATOM   7636 C CB  . ARG A 1 1132 ? 165.115 131.966 78.524  1.00 149.21 ? 1091 ARG A CB  1 
ATOM   7637 C CG  . ARG A 1 1132 ? 165.050 131.393 79.930  1.00 149.21 ? 1091 ARG A CG  1 
ATOM   7638 C CD  . ARG A 1 1132 ? 163.717 130.707 80.182  1.00 149.21 ? 1091 ARG A CD  1 
ATOM   7639 N NE  . ARG A 1 1132 ? 163.416 129.729 79.142  1.00 149.21 ? 1091 ARG A NE  1 
ATOM   7640 C CZ  . ARG A 1 1132 ? 164.007 128.547 79.030  1.00 149.21 ? 1091 ARG A CZ  1 
ATOM   7641 N NH1 . ARG A 1 1132 ? 164.917 128.143 79.901  1.00 149.21 ? 1091 ARG A NH1 1 
ATOM   7642 N NH2 . ARG A 1 1132 ? 163.678 127.751 78.017  1.00 149.21 ? 1091 ARG A NH2 1 
ATOM   7643 N N   . LYS A 1 1133 ? 164.642 134.949 79.039  1.00 156.26 ? 1092 LYS A N   1 
ATOM   7644 C CA  . LYS A 1 1133 ? 164.527 136.157 79.843  1.00 156.26 ? 1092 LYS A CA  1 
ATOM   7645 C C   . LYS A 1 1133 ? 163.495 137.127 79.294  1.00 156.26 ? 1092 LYS A C   1 
ATOM   7646 O O   . LYS A 1 1133 ? 163.112 138.066 79.998  1.00 156.26 ? 1092 LYS A O   1 
ATOM   7647 C CB  . LYS A 1 1133 ? 165.883 136.863 79.941  1.00 156.26 ? 1092 LYS A CB  1 
ATOM   7648 C CG  . LYS A 1 1133 ? 166.276 137.618 78.683  1.00 156.26 ? 1092 LYS A CG  1 
ATOM   7649 C CD  . LYS A 1 1133 ? 167.785 137.663 78.514  1.00 156.26 ? 1092 LYS A CD  1 
ATOM   7650 C CE  . LYS A 1 1133 ? 168.377 138.881 79.203  1.00 156.26 ? 1092 LYS A CE  1 
ATOM   7651 N NZ  . LYS A 1 1133 ? 169.841 139.000 78.967  1.00 156.26 ? 1092 LYS A NZ  1 
ATOM   7652 N N   . TYR A 1 1134 ? 163.037 136.919 78.065  1.00 155.47 ? 1093 TYR A N   1 
ATOM   7653 C CA  . TYR A 1 1134 ? 162.073 137.806 77.442  1.00 155.47 ? 1093 TYR A CA  1 
ATOM   7654 C C   . TYR A 1 1134 ? 160.684 137.568 78.030  1.00 155.47 ? 1093 TYR A C   1 
ATOM   7655 O O   . TYR A 1 1134 ? 160.419 136.548 78.673  1.00 155.47 ? 1093 TYR A O   1 
ATOM   7656 C CB  . TYR A 1 1134 ? 162.052 137.577 75.932  1.00 155.47 ? 1093 TYR A CB  1 
ATOM   7657 C CG  . TYR A 1 1134 ? 161.582 138.753 75.115  1.00 155.47 ? 1093 TYR A CG  1 
ATOM   7658 C CD1 . TYR A 1 1134 ? 162.462 139.764 74.755  1.00 155.47 ? 1093 TYR A CD1 1 
ATOM   7659 C CD2 . TYR A 1 1134 ? 160.265 138.857 74.706  1.00 155.47 ? 1093 TYR A CD2 1 
ATOM   7660 C CE1 . TYR A 1 1134 ? 162.042 140.837 74.004  1.00 155.47 ? 1093 TYR A CE1 1 
ATOM   7661 C CE2 . TYR A 1 1134 ? 159.835 139.928 73.957  1.00 155.47 ? 1093 TYR A CE2 1 
ATOM   7662 C CZ  . TYR A 1 1134 ? 160.728 140.916 73.609  1.00 155.47 ? 1093 TYR A CZ  1 
ATOM   7663 O OH  . TYR A 1 1134 ? 160.303 141.985 72.861  1.00 155.47 ? 1093 TYR A OH  1 
ATOM   7664 N N   . ASN A 1 1135 ? 159.793 138.525 77.803  1.00 154.24 ? 1094 ASN A N   1 
ATOM   7665 C CA  . ASN A 1 1135 ? 158.421 138.407 78.279  1.00 154.24 ? 1094 ASN A CA  1 
ATOM   7666 C C   . ASN A 1 1135 ? 157.606 137.550 77.319  1.00 154.24 ? 1094 ASN A C   1 
ATOM   7667 O O   . ASN A 1 1135 ? 157.519 137.850 76.125  1.00 154.24 ? 1094 ASN A O   1 
ATOM   7668 C CB  . ASN A 1 1135 ? 157.792 139.790 78.424  1.00 154.24 ? 1094 ASN A CB  1 
ATOM   7669 C CG  . ASN A 1 1135 ? 158.666 140.745 79.212  1.00 154.24 ? 1094 ASN A CG  1 
ATOM   7670 O OD1 . ASN A 1 1135 ? 159.118 140.427 80.312  1.00 154.24 ? 1094 ASN A OD1 1 
ATOM   7671 N ND2 . ASN A 1 1135 ? 158.910 141.925 78.652  1.00 154.24 ? 1094 ASN A ND2 1 
ATOM   7672 N N   . LEU A 1 1136 ? 157.006 136.480 77.845  1.00 137.31 ? 1095 LEU A N   1 
ATOM   7673 C CA  . LEU A 1 1136 ? 156.230 135.579 76.999  1.00 137.31 ? 1095 LEU A CA  1 
ATOM   7674 C C   . LEU A 1 1136 ? 154.935 136.229 76.532  1.00 137.31 ? 1095 LEU A C   1 
ATOM   7675 O O   . LEU A 1 1136 ? 154.509 136.026 75.388  1.00 137.31 ? 1095 LEU A O   1 
ATOM   7676 C CB  . LEU A 1 1136 ? 155.934 134.278 77.743  1.00 137.31 ? 1095 LEU A CB  1 
ATOM   7677 C CG  . LEU A 1 1136 ? 155.178 133.222 76.939  1.00 137.31 ? 1095 LEU A CG  1 
ATOM   7678 C CD1 . LEU A 1 1136 ? 155.974 132.825 75.710  1.00 137.31 ? 1095 LEU A CD1 1 
ATOM   7679 C CD2 . LEU A 1 1136 ? 154.878 132.006 77.795  1.00 137.31 ? 1095 LEU A CD2 1 
ATOM   7680 N N   . LYS A 1 1137 ? 154.294 137.008 77.405  1.00 132.55 ? 1096 LYS A N   1 
ATOM   7681 C CA  . LYS A 1 1137 ? 153.014 137.614 77.058  1.00 132.55 ? 1096 LYS A CA  1 
ATOM   7682 C C   . LYS A 1 1137 ? 153.155 138.563 75.876  1.00 132.55 ? 1096 LYS A C   1 
ATOM   7683 O O   . LYS A 1 1137 ? 152.301 138.586 74.983  1.00 132.55 ? 1096 LYS A O   1 
ATOM   7684 C CB  . LYS A 1 1137 ? 152.442 138.349 78.271  1.00 132.55 ? 1096 LYS A CB  1 
ATOM   7685 C CG  . LYS A 1 1137 ? 150.973 138.726 78.150  1.00 132.55 ? 1096 LYS A CG  1 
ATOM   7686 C CD  . LYS A 1 1137 ? 150.086 137.539 77.787  1.00 132.55 ? 1096 LYS A CD  1 
ATOM   7687 C CE  . LYS A 1 1137 ? 150.307 136.340 78.705  1.00 132.55 ? 1096 LYS A CE  1 
ATOM   7688 N NZ  . LYS A 1 1137 ? 149.092 135.489 78.801  1.00 132.55 ? 1096 LYS A NZ  1 
ATOM   7689 N N   . ALA A 1 1138 ? 154.226 139.358 75.856  1.00 135.91 ? 1097 ALA A N   1 
ATOM   7690 C CA  . ALA A 1 1138 ? 154.479 140.227 74.714  1.00 135.91 ? 1097 ALA A CA  1 
ATOM   7691 C C   . ALA A 1 1138 ? 154.799 139.426 73.459  1.00 135.91 ? 1097 ALA A C   1 
ATOM   7692 O O   . ALA A 1 1138 ? 154.446 139.847 72.351  1.00 135.91 ? 1097 ALA A O   1 
ATOM   7693 C CB  . ALA A 1 1138 ? 155.617 141.196 75.031  1.00 135.91 ? 1097 ALA A CB  1 
ATOM   7694 N N   . ILE A 1 1139 ? 155.474 138.287 73.608  1.00 136.24 ? 1098 ILE A N   1 
ATOM   7695 C CA  . ILE A 1 1139 ? 155.792 137.454 72.455  1.00 136.24 ? 1098 ILE A CA  1 
ATOM   7696 C C   . ILE A 1 1139 ? 154.523 136.898 71.825  1.00 136.24 ? 1098 ILE A C   1 
ATOM   7697 O O   . ILE A 1 1139 ? 154.392 136.863 70.596  1.00 136.24 ? 1098 ILE A O   1 
ATOM   7698 C CB  . ILE A 1 1139 ? 156.762 136.331 72.864  1.00 136.24 ? 1098 ILE A CB  1 
ATOM   7699 C CG1 . ILE A 1 1139 ? 158.183 136.875 72.951  1.00 136.24 ? 1098 ILE A CG1 1 
ATOM   7700 C CG2 . ILE A 1 1139 ? 156.694 135.169 71.886  1.00 136.24 ? 1098 ILE A CG2 1 
ATOM   7701 C CD1 . ILE A 1 1139 ? 158.689 137.459 71.652  1.00 136.24 ? 1098 ILE A CD1 1 
ATOM   7702 N N   . ARG A 1 1140 ? 153.568 136.465 72.653  1.00 128.50 ? 1099 ARG A N   1 
ATOM   7703 C CA  . ARG A 1 1140 ? 152.369 135.811 72.134  1.00 128.50 ? 1099 ARG A CA  1 
ATOM   7704 C C   . ARG A 1 1140 ? 151.657 136.678 71.101  1.00 128.50 ? 1099 ARG A C   1 
ATOM   7705 O O   . ARG A 1 1140 ? 151.171 136.169 70.085  1.00 128.50 ? 1099 ARG A O   1 
ATOM   7706 C CB  . ARG A 1 1140 ? 151.416 135.473 73.279  1.00 128.50 ? 1099 ARG A CB  1 
ATOM   7707 C CG  . ARG A 1 1140 ? 151.976 134.529 74.327  1.00 128.50 ? 1099 ARG A CG  1 
ATOM   7708 C CD  . ARG A 1 1140 ? 152.065 133.100 73.828  1.00 128.50 ? 1099 ARG A CD  1 
ATOM   7709 N NE  . ARG A 1 1140 ? 152.351 132.181 74.923  1.00 128.50 ? 1099 ARG A NE  1 
ATOM   7710 C CZ  . ARG A 1 1140 ? 152.481 130.868 74.789  1.00 128.50 ? 1099 ARG A CZ  1 
ATOM   7711 N NH1 . ARG A 1 1140 ? 152.354 130.278 73.614  1.00 128.50 ? 1099 ARG A NH1 1 
ATOM   7712 N NH2 . ARG A 1 1140 ? 152.742 130.131 75.864  1.00 128.50 ? 1099 ARG A NH2 1 
ATOM   7713 N N   . LYS A 1 1141 ? 151.586 137.988 71.338  1.00 132.47 ? 1100 LYS A N   1 
ATOM   7714 C CA  . LYS A 1 1141 ? 150.897 138.868 70.405  1.00 132.47 ? 1100 LYS A CA  1 
ATOM   7715 C C   . LYS A 1 1141 ? 151.729 139.205 69.175  1.00 132.47 ? 1100 LYS A C   1 
ATOM   7716 O O   . LYS A 1 1141 ? 151.196 139.799 68.233  1.00 132.47 ? 1100 LYS A O   1 
ATOM   7717 C CB  . LYS A 1 1141 ? 150.466 140.160 71.104  1.00 132.47 ? 1100 LYS A CB  1 
ATOM   7718 C CG  . LYS A 1 1141 ? 151.609 141.035 71.578  1.00 132.47 ? 1100 LYS A CG  1 
ATOM   7719 C CD  . LYS A 1 1141 ? 151.087 142.314 72.220  1.00 132.47 ? 1100 LYS A CD  1 
ATOM   7720 C CE  . LYS A 1 1141 ? 150.455 142.049 73.578  1.00 132.47 ? 1100 LYS A CE  1 
ATOM   7721 N NZ  . LYS A 1 1141 ? 151.447 141.583 74.584  1.00 132.47 ? 1100 LYS A NZ  1 
ATOM   7722 N N   . HIS A 1 1142 ? 153.010 138.844 69.157  1.00 136.59 ? 1101 HIS A N   1 
ATOM   7723 C CA  . HIS A 1 1142 ? 153.857 139.027 67.985  1.00 136.59 ? 1101 HIS A CA  1 
ATOM   7724 C C   . HIS A 1 1142 ? 154.074 137.728 67.222  1.00 136.59 ? 1101 HIS A C   1 
ATOM   7725 O O   . HIS A 1 1142 ? 154.925 137.679 66.329  1.00 136.59 ? 1101 HIS A O   1 
ATOM   7726 C CB  . HIS A 1 1142 ? 155.202 139.629 68.391  1.00 136.59 ? 1101 HIS A CB  1 
ATOM   7727 C CG  . HIS A 1 1142 ? 155.086 140.942 69.098  1.00 136.59 ? 1101 HIS A CG  1 
ATOM   7728 N ND1 . HIS A 1 1142 ? 153.956 141.728 69.024  1.00 136.59 ? 1101 HIS A ND1 1 
ATOM   7729 C CD2 . HIS A 1 1142 ? 155.957 141.609 69.891  1.00 136.59 ? 1101 HIS A CD2 1 
ATOM   7730 C CE1 . HIS A 1 1142 ? 154.136 142.822 69.742  1.00 136.59 ? 1101 HIS A CE1 1 
ATOM   7731 N NE2 . HIS A 1 1142 ? 155.342 142.774 70.278  1.00 136.59 ? 1101 HIS A NE2 1 
ATOM   7732 N N   . ILE A 1 1143 ? 153.329 136.677 67.552  1.00 131.71 ? 1102 ILE A N   1 
ATOM   7733 C CA  . ILE A 1 1143 ? 153.452 135.376 66.909  1.00 131.71 ? 1102 ILE A CA  1 
ATOM   7734 C C   . ILE A 1 1143 ? 152.076 134.962 66.414  1.00 131.71 ? 1102 ILE A C   1 
ATOM   7735 O O   . ILE A 1 1143 ? 151.102 135.012 67.172  1.00 131.71 ? 1102 ILE A O   1 
ATOM   7736 C CB  . ILE A 1 1143 ? 154.010 134.314 67.876  1.00 131.71 ? 1102 ILE A CB  1 
ATOM   7737 C CG1 . ILE A 1 1143 ? 155.383 134.729 68.403  1.00 131.71 ? 1102 ILE A CG1 1 
ATOM   7738 C CG2 . ILE A 1 1143 ? 154.088 132.960 67.194  1.00 131.71 ? 1102 ILE A CG2 1 
ATOM   7739 C CD1 . ILE A 1 1143 ? 156.421 134.884 67.335  1.00 131.71 ? 1102 ILE A CD1 1 
ATOM   7740 N N   . ALA A 1 1144 ? 151.992 134.548 65.154  1.00 130.17 ? 1103 ALA A N   1 
ATOM   7741 C CA  . ALA A 1 1144 ? 150.763 134.014 64.588  1.00 130.17 ? 1103 ALA A CA  1 
ATOM   7742 C C   . ALA A 1 1144 ? 150.972 132.541 64.286  1.00 130.17 ? 1103 ALA A C   1 
ATOM   7743 O O   . ALA A 1 1144 ? 152.062 132.137 63.880  1.00 130.17 ? 1103 ALA A O   1 
ATOM   7744 C CB  . ALA A 1 1144 ? 150.359 134.765 63.319  1.00 130.17 ? 1103 ALA A CB  1 
ATOM   7745 N N   . ILE A 1 1145 ? 149.938 131.735 64.503  1.00 128.46 ? 1104 ILE A N   1 
ATOM   7746 C CA  . ILE A 1 1145 ? 150.031 130.290 64.340  1.00 128.46 ? 1104 ILE A CA  1 
ATOM   7747 C C   . ILE A 1 1145 ? 148.761 129.770 63.681  1.00 128.46 ? 1104 ILE A C   1 
ATOM   7748 O O   . ILE A 1 1145 ? 147.660 130.260 63.954  1.00 128.46 ? 1104 ILE A O   1 
ATOM   7749 C CB  . ILE A 1 1145 ? 150.283 129.585 65.692  1.00 128.46 ? 1104 ILE A CB  1 
ATOM   7750 C CG1 . ILE A 1 1145 ? 150.630 128.112 65.478  1.00 128.46 ? 1104 ILE A CG1 1 
ATOM   7751 C CG2 . ILE A 1 1145 ? 149.092 129.736 66.623  1.00 128.46 ? 1104 ILE A CG2 1 
ATOM   7752 C CD1 . ILE A 1 1145 ? 151.197 127.442 66.707  1.00 128.46 ? 1104 ILE A CD1 1 
ATOM   7753 N N   . VAL A 1 1146 ? 148.922 128.804 62.788  1.00 134.38 ? 1105 VAL A N   1 
ATOM   7754 C CA  . VAL A 1 1146 ? 147.813 128.051 62.221  1.00 134.38 ? 1105 VAL A CA  1 
ATOM   7755 C C   . VAL A 1 1146 ? 147.998 126.582 62.585  1.00 134.38 ? 1105 VAL A C   1 
ATOM   7756 O O   . VAL A 1 1146 ? 149.048 125.992 62.328  1.00 134.38 ? 1105 VAL A O   1 
ATOM   7757 C CB  . VAL A 1 1146 ? 147.707 128.249 60.697  1.00 134.38 ? 1105 VAL A CB  1 
ATOM   7758 C CG1 . VAL A 1 1146 ? 147.462 129.711 60.377  1.00 134.38 ? 1105 VAL A CG1 1 
ATOM   7759 C CG2 . VAL A 1 1146 ? 148.964 127.780 59.989  1.00 134.38 ? 1105 VAL A CG2 1 
ATOM   7760 N N   . PRO A 1 1147 ? 147.021 125.971 63.246  1.00 141.23 ? 1106 PRO A N   1 
ATOM   7761 C CA  . PRO A 1 1147 ? 147.124 124.544 63.553  1.00 141.23 ? 1106 PRO A CA  1 
ATOM   7762 C C   . PRO A 1 1147 ? 146.924 123.695 62.308  1.00 141.23 ? 1106 PRO A C   1 
ATOM   7763 O O   . PRO A 1 1147 ? 146.355 124.131 61.305  1.00 141.23 ? 1106 PRO A O   1 
ATOM   7764 C CB  . PRO A 1 1147 ? 145.999 124.313 64.566  1.00 141.23 ? 1106 PRO A CB  1 
ATOM   7765 C CG  . PRO A 1 1147 ? 145.028 125.408 64.299  1.00 141.23 ? 1106 PRO A CG  1 
ATOM   7766 C CD  . PRO A 1 1147 ? 145.846 126.591 63.879  1.00 141.23 ? 1106 PRO A CD  1 
ATOM   7767 N N   . GLN A 1 1148 ? 147.416 122.457 62.386  1.00 149.04 ? 1107 GLN A N   1 
ATOM   7768 C CA  . GLN A 1 1148 ? 147.179 121.504 61.306  1.00 149.04 ? 1107 GLN A CA  1 
ATOM   7769 C C   . GLN A 1 1148 ? 145.692 121.197 61.170  1.00 149.04 ? 1107 GLN A C   1 
ATOM   7770 O O   . GLN A 1 1148 ? 145.183 121.033 60.056  1.00 149.04 ? 1107 GLN A O   1 
ATOM   7771 C CB  . GLN A 1 1148 ? 147.991 120.229 61.540  1.00 149.04 ? 1107 GLN A CB  1 
ATOM   7772 C CG  . GLN A 1 1148 ? 147.524 119.374 62.707  1.00 149.04 ? 1107 GLN A CG  1 
ATOM   7773 C CD  . GLN A 1 1148 ? 148.094 119.833 64.034  1.00 149.04 ? 1107 GLN A CD  1 
ATOM   7774 O OE1 . GLN A 1 1148 ? 148.592 120.953 64.155  1.00 149.04 ? 1107 GLN A OE1 1 
ATOM   7775 N NE2 . GLN A 1 1148 ? 148.018 118.971 65.039  1.00 149.04 ? 1107 GLN A NE2 1 
ATOM   7776 N N   . GLU A 1 1149 ? 144.983 121.113 62.292  1.00 146.06 ? 1108 GLU A N   1 
ATOM   7777 C CA  . GLU A 1 1149 ? 143.534 120.965 62.294  1.00 146.06 ? 1108 GLU A CA  1 
ATOM   7778 C C   . GLU A 1 1149 ? 142.913 122.226 62.871  1.00 146.06 ? 1108 GLU A C   1 
ATOM   7779 O O   . GLU A 1 1149 ? 143.010 122.454 64.087  1.00 146.06 ? 1108 GLU A O   1 
ATOM   7780 C CB  . GLU A 1 1149 ? 143.109 119.740 63.104  1.00 146.06 ? 1108 GLU A CB  1 
ATOM   7781 C CG  . GLU A 1 1149 ? 141.635 119.394 62.969  1.00 146.06 ? 1108 GLU A CG  1 
ATOM   7782 C CD  . GLU A 1 1149 ? 140.805 119.903 64.131  1.00 146.06 ? 1108 GLU A CD  1 
ATOM   7783 O OE1 . GLU A 1 1149 ? 141.397 120.357 65.134  1.00 146.06 ? 1108 GLU A OE1 1 
ATOM   7784 O OE2 . GLU A 1 1149 ? 139.561 119.851 64.045  1.00 146.06 ? 1108 GLU A OE2 1 
ATOM   7785 N N   . PRO A 1 1150 ? 142.290 123.077 62.058  1.00 146.54 ? 1109 PRO A N   1 
ATOM   7786 C CA  . PRO A 1 1150 ? 141.665 124.286 62.600  1.00 146.54 ? 1109 PRO A CA  1 
ATOM   7787 C C   . PRO A 1 1150 ? 140.534 123.941 63.555  1.00 146.54 ? 1109 PRO A C   1 
ATOM   7788 O O   . PRO A 1 1150 ? 139.829 122.943 63.389  1.00 146.54 ? 1109 PRO A O   1 
ATOM   7789 C CB  . PRO A 1 1150 ? 141.149 125.011 61.352  1.00 146.54 ? 1109 PRO A CB  1 
ATOM   7790 C CG  . PRO A 1 1150 ? 141.007 123.940 60.324  1.00 146.54 ? 1109 PRO A CG  1 
ATOM   7791 C CD  . PRO A 1 1150 ? 142.098 122.953 60.603  1.00 146.54 ? 1109 PRO A CD  1 
ATOM   7792 N N   . CYS A 1 1151 ? 140.367 124.784 64.570  1.00 138.15 ? 1110 CYS A N   1 
ATOM   7793 C CA  . CYS A 1 1151 ? 139.394 124.555 65.626  1.00 138.15 ? 1110 CYS A CA  1 
ATOM   7794 C C   . CYS A 1 1151 ? 138.384 125.693 65.660  1.00 138.15 ? 1110 CYS A C   1 
ATOM   7795 O O   . CYS A 1 1151 ? 138.683 126.824 65.262  1.00 138.15 ? 1110 CYS A O   1 
ATOM   7796 C CB  . CYS A 1 1151 ? 140.085 124.418 66.985  1.00 138.15 ? 1110 CYS A CB  1 
ATOM   7797 S SG  . CYS A 1 1151 ? 141.439 123.219 67.019  1.00 138.15 ? 1110 CYS A SG  1 
ATOM   7798 N N   . LEU A 1 1152 ? 137.183 125.383 66.141  1.00 136.49 ? 1111 LEU A N   1 
ATOM   7799 C CA  . LEU A 1 1152 ? 136.058 126.313 66.126  1.00 136.49 ? 1111 LEU A CA  1 
ATOM   7800 C C   . LEU A 1 1152 ? 135.858 126.867 67.533  1.00 136.49 ? 1111 LEU A C   1 
ATOM   7801 O O   . LEU A 1 1152 ? 135.421 126.146 68.434  1.00 136.49 ? 1111 LEU A O   1 
ATOM   7802 C CB  . LEU A 1 1152 ? 134.792 125.618 65.627  1.00 136.49 ? 1111 LEU A CB  1 
ATOM   7803 C CG  . LEU A 1 1152 ? 134.593 125.445 64.115  1.00 136.49 ? 1111 LEU A CG  1 
ATOM   7804 C CD1 . LEU A 1 1152 ? 134.559 126.793 63.410  1.00 136.49 ? 1111 LEU A CD1 1 
ATOM   7805 C CD2 . LEU A 1 1152 ? 135.645 124.533 63.492  1.00 136.49 ? 1111 LEU A CD2 1 
ATOM   7806 N N   . PHE A 1 1153 ? 136.175 128.151 67.718  1.00 129.99 ? 1112 PHE A N   1 
ATOM   7807 C CA  . PHE A 1 1153 ? 136.065 128.759 69.042  1.00 129.99 ? 1112 PHE A CA  1 
ATOM   7808 C C   . PHE A 1 1153 ? 134.616 128.850 69.505  1.00 129.99 ? 1112 PHE A C   1 
ATOM   7809 O O   . PHE A 1 1153 ? 134.286 128.424 70.615  1.00 129.99 ? 1112 PHE A O   1 
ATOM   7810 C CB  . PHE A 1 1153 ? 136.705 130.146 69.046  1.00 129.99 ? 1112 PHE A CB  1 
ATOM   7811 C CG  . PHE A 1 1153 ? 138.190 130.127 68.885  1.00 129.99 ? 1112 PHE A CG  1 
ATOM   7812 C CD1 . PHE A 1 1153 ? 138.996 129.630 69.894  1.00 129.99 ? 1112 PHE A CD1 1 
ATOM   7813 C CD2 . PHE A 1 1153 ? 138.784 130.605 67.730  1.00 129.99 ? 1112 PHE A CD2 1 
ATOM   7814 C CE1 . PHE A 1 1153 ? 140.366 129.610 69.755  1.00 129.99 ? 1112 PHE A CE1 1 
ATOM   7815 C CE2 . PHE A 1 1153 ? 140.155 130.587 67.583  1.00 129.99 ? 1112 PHE A CE2 1 
ATOM   7816 C CZ  . PHE A 1 1153 ? 140.947 130.087 68.596  1.00 129.99 ? 1112 PHE A CZ  1 
ATOM   7817 N N   . GLY A 1 1154 ? 133.744 129.396 68.682  1.00 139.82 ? 1113 GLY A N   1 
ATOM   7818 C CA  . GLY A 1 1154 ? 132.392 129.684 69.117  1.00 139.82 ? 1113 GLY A CA  1 
ATOM   7819 C C   . GLY A 1 1154 ? 131.383 129.712 68.002  1.00 139.82 ? 1113 GLY A C   1 
ATOM   7820 O O   . GLY A 1 1154 ? 131.600 129.141 66.930  1.00 139.82 ? 1113 GLY A O   1 
ATOM   7821 N N   . THR A 1 1155 ? 130.263 130.385 68.266  1.00 151.11 ? 1114 THR A N   1 
ATOM   7822 C CA  . THR A 1 1155 ? 129.142 130.388 67.334  1.00 151.11 ? 1114 THR A CA  1 
ATOM   7823 C C   . THR A 1 1155 ? 129.519 131.046 66.011  1.00 151.11 ? 1114 THR A C   1 
ATOM   7824 O O   . THR A 1 1155 ? 129.536 130.396 64.960  1.00 151.11 ? 1114 THR A O   1 
ATOM   7825 C CB  . THR A 1 1155 ? 127.943 131.100 67.970  1.00 151.11 ? 1114 THR A CB  1 
ATOM   7826 O OG1 . THR A 1 1155 ? 127.405 130.289 69.023  1.00 151.11 ? 1114 THR A OG1 1 
ATOM   7827 C CG2 . THR A 1 1155 ? 126.857 131.372 66.935  1.00 151.11 ? 1114 THR A CG2 1 
ATOM   7828 N N   . THR A 1 1156 ? 129.839 132.332 66.048  1.00 146.00 ? 1115 THR A N   1 
ATOM   7829 C CA  . THR A 1 1156 ? 129.995 133.115 64.834  1.00 146.00 ? 1115 THR A CA  1 
ATOM   7830 C C   . THR A 1 1156 ? 131.393 132.965 64.252  1.00 146.00 ? 1115 THR A C   1 
ATOM   7831 O O   . THR A 1 1156 ? 132.379 132.807 64.975  1.00 146.00 ? 1115 THR A O   1 
ATOM   7832 C CB  . THR A 1 1156 ? 129.716 134.593 65.107  1.00 146.00 ? 1115 THR A CB  1 
ATOM   7833 O OG1 . THR A 1 1156 ? 130.859 135.184 65.735  1.00 146.00 ? 1115 THR A OG1 1 
ATOM   7834 C CG2 . THR A 1 1156 ? 128.508 134.750 66.016  1.00 146.00 ? 1115 THR A CG2 1 
ATOM   7835 N N   . ILE A 1 1157 ? 131.466 133.010 62.921  1.00 146.41 ? 1116 ILE A N   1 
ATOM   7836 C CA  . ILE A 1 1157 ? 132.753 133.188 62.263  1.00 146.41 ? 1116 ILE A CA  1 
ATOM   7837 C C   . ILE A 1 1157 ? 133.321 134.559 62.609  1.00 146.41 ? 1116 ILE A C   1 
ATOM   7838 O O   . ILE A 1 1157 ? 134.543 134.740 62.667  1.00 146.41 ? 1116 ILE A O   1 
ATOM   7839 C CB  . ILE A 1 1157 ? 132.599 132.981 60.744  1.00 146.41 ? 1116 ILE A CB  1 
ATOM   7840 C CG1 . ILE A 1 1157 ? 132.486 131.489 60.427  1.00 146.41 ? 1116 ILE A CG1 1 
ATOM   7841 C CG2 . ILE A 1 1157 ? 133.758 133.596 59.975  1.00 146.41 ? 1116 ILE A CG2 1 
ATOM   7842 C CD1 . ILE A 1 1157 ? 132.503 131.172 58.949  1.00 146.41 ? 1116 ILE A CD1 1 
ATOM   7843 N N   . TYR A 1 1158 ? 132.444 135.532 62.863  1.00 144.83 ? 1117 TYR A N   1 
ATOM   7844 C CA  . TYR A 1 1158 ? 132.862 136.839 63.361  1.00 144.83 ? 1117 TYR A CA  1 
ATOM   7845 C C   . TYR A 1 1158 ? 133.848 136.714 64.516  1.00 144.83 ? 1117 TYR A C   1 
ATOM   7846 O O   . TYR A 1 1158 ? 134.974 137.223 64.448  1.00 144.83 ? 1117 TYR A O   1 
ATOM   7847 C CB  . TYR A 1 1158 ? 131.627 137.624 63.804  1.00 144.83 ? 1117 TYR A CB  1 
ATOM   7848 C CG  . TYR A 1 1158 ? 131.855 139.095 64.038  1.00 144.83 ? 1117 TYR A CG  1 
ATOM   7849 C CD1 . TYR A 1 1158 ? 132.659 139.840 63.194  1.00 144.83 ? 1117 TYR A CD1 1 
ATOM   7850 C CD2 . TYR A 1 1158 ? 131.270 139.736 65.123  1.00 144.83 ? 1117 TYR A CD2 1 
ATOM   7851 C CE1 . TYR A 1 1158 ? 132.864 141.187 63.416  1.00 144.83 ? 1117 TYR A CE1 1 
ATOM   7852 C CE2 . TYR A 1 1158 ? 131.473 141.081 65.353  1.00 144.83 ? 1117 TYR A CE2 1 
ATOM   7853 C CZ  . TYR A 1 1158 ? 132.272 141.802 64.497  1.00 144.83 ? 1117 TYR A CZ  1 
ATOM   7854 O OH  . TYR A 1 1158 ? 132.479 143.144 64.719  1.00 144.83 ? 1117 TYR A OH  1 
ATOM   7855 N N   . GLU A 1 1159 ? 133.444 136.023 65.583  1.00 142.06 ? 1118 GLU A N   1 
ATOM   7856 C CA  . GLU A 1 1159 ? 134.296 135.930 66.764  1.00 142.06 ? 1118 GLU A CA  1 
ATOM   7857 C C   . GLU A 1 1159 ? 135.519 135.057 66.514  1.00 142.06 ? 1118 GLU A C   1 
ATOM   7858 O O   . GLU A 1 1159 ? 136.588 135.329 67.070  1.00 142.06 ? 1118 GLU A O   1 
ATOM   7859 C CB  . GLU A 1 1159 ? 133.490 135.411 67.955  1.00 142.06 ? 1118 GLU A CB  1 
ATOM   7860 C CG  . GLU A 1 1159 ? 133.074 133.956 67.850  1.00 142.06 ? 1118 GLU A CG  1 
ATOM   7861 C CD  . GLU A 1 1159 ? 131.795 133.665 68.601  1.00 142.06 ? 1118 GLU A CD  1 
ATOM   7862 O OE1 . GLU A 1 1159 ? 131.628 134.191 69.722  1.00 142.06 ? 1118 GLU A OE1 1 
ATOM   7863 O OE2 . GLU A 1 1159 ? 130.952 132.917 68.067  1.00 142.06 ? 1118 GLU A OE2 1 
ATOM   7864 N N   . ASN A 1 1160 ? 135.396 134.019 65.683  1.00 134.33 ? 1119 ASN A N   1 
ATOM   7865 C CA  . ASN A 1 1160 ? 136.556 133.188 65.383  1.00 134.33 ? 1119 ASN A CA  1 
ATOM   7866 C C   . ASN A 1 1160 ? 137.637 133.989 64.670  1.00 134.33 ? 1119 ASN A C   1 
ATOM   7867 O O   . ASN A 1 1160 ? 138.829 133.841 64.967  1.00 134.33 ? 1119 ASN A O   1 
ATOM   7868 C CB  . ASN A 1 1160 ? 136.140 131.983 64.544  1.00 134.33 ? 1119 ASN A CB  1 
ATOM   7869 C CG  . ASN A 1 1160 ? 135.386 130.951 65.349  1.00 134.33 ? 1119 ASN A CG  1 
ATOM   7870 O OD1 . ASN A 1 1160 ? 134.847 131.251 66.412  1.00 134.33 ? 1119 ASN A OD1 1 
ATOM   7871 N ND2 . ASN A 1 1160 ? 135.349 129.723 64.849  1.00 134.33 ? 1119 ASN A ND2 1 
ATOM   7872 N N   . ILE A 1 1161 ? 137.244 134.842 63.724  1.00 135.52 ? 1120 ILE A N   1 
ATOM   7873 C CA  . ILE A 1 1161 ? 138.215 135.698 63.053  1.00 135.52 ? 1120 ILE A CA  1 
ATOM   7874 C C   . ILE A 1 1161 ? 138.739 136.766 64.005  1.00 135.52 ? 1120 ILE A C   1 
ATOM   7875 O O   . ILE A 1 1161 ? 139.933 137.090 63.995  1.00 135.52 ? 1120 ILE A O   1 
ATOM   7876 C CB  . ILE A 1 1161 ? 137.599 136.315 61.784  1.00 135.52 ? 1120 ILE A CB  1 
ATOM   7877 C CG1 . ILE A 1 1161 ? 137.006 135.224 60.892  1.00 135.52 ? 1120 ILE A CG1 1 
ATOM   7878 C CG2 . ILE A 1 1161 ? 138.636 137.107 61.015  1.00 135.52 ? 1120 ILE A CG2 1 
ATOM   7879 C CD1 . ILE A 1 1161 ? 138.033 134.268 60.330  1.00 135.52 ? 1120 ILE A CD1 1 
ATOM   7880 N N   . ALA A 1 1162 ? 137.866 137.329 64.844  1.00 130.01 ? 1121 ALA A N   1 
ATOM   7881 C CA  . ALA A 1 1162 ? 138.298 138.370 65.768  1.00 130.01 ? 1121 ALA A CA  1 
ATOM   7882 C C   . ALA A 1 1162 ? 139.215 137.837 66.859  1.00 130.01 ? 1121 ALA A C   1 
ATOM   7883 O O   . ALA A 1 1162 ? 139.935 138.622 67.484  1.00 130.01 ? 1121 ALA A O   1 
ATOM   7884 C CB  . ALA A 1 1162 ? 137.085 139.054 66.399  1.00 130.01 ? 1121 ALA A CB  1 
ATOM   7885 N N   . TYR A 1 1163 ? 139.197 136.526 67.103  1.00 121.78 ? 1122 TYR A N   1 
ATOM   7886 C CA  . TYR A 1 1163 ? 140.038 135.923 68.129  1.00 121.78 ? 1122 TYR A CA  1 
ATOM   7887 C C   . TYR A 1 1163 ? 141.523 136.144 67.876  1.00 121.78 ? 1122 TYR A C   1 
ATOM   7888 O O   . TYR A 1 1163 ? 142.315 136.073 68.819  1.00 121.78 ? 1122 TYR A O   1 
ATOM   7889 C CB  . TYR A 1 1163 ? 139.748 134.426 68.209  1.00 121.78 ? 1122 TYR A CB  1 
ATOM   7890 C CG  . TYR A 1 1163 ? 140.163 133.770 69.501  1.00 121.78 ? 1122 TYR A CG  1 
ATOM   7891 C CD1 . TYR A 1 1163 ? 141.432 133.234 69.656  1.00 121.78 ? 1122 TYR A CD1 1 
ATOM   7892 C CD2 . TYR A 1 1163 ? 139.279 133.674 70.566  1.00 121.78 ? 1122 TYR A CD2 1 
ATOM   7893 C CE1 . TYR A 1 1163 ? 141.811 132.626 70.836  1.00 121.78 ? 1122 TYR A CE1 1 
ATOM   7894 C CE2 . TYR A 1 1163 ? 139.648 133.068 71.747  1.00 121.78 ? 1122 TYR A CE2 1 
ATOM   7895 C CZ  . TYR A 1 1163 ? 140.914 132.547 71.877  1.00 121.78 ? 1122 TYR A CZ  1 
ATOM   7896 O OH  . TYR A 1 1163 ? 141.283 131.943 73.052  1.00 121.78 ? 1122 TYR A OH  1 
ATOM   7897 N N   . GLY A 1 1164 ? 141.913 136.408 66.628  1.00 127.68 ? 1123 GLY A N   1 
ATOM   7898 C CA  . GLY A 1 1164 ? 143.323 136.578 66.324  1.00 127.68 ? 1123 GLY A CA  1 
ATOM   7899 C C   . GLY A 1 1164 ? 143.946 137.759 67.042  1.00 127.68 ? 1123 GLY A C   1 
ATOM   7900 O O   . GLY A 1 1164 ? 145.078 137.677 67.520  1.00 127.68 ? 1123 GLY A O   1 
ATOM   7901 N N   . HIS A 1 1165 ? 143.222 138.870 67.128  1.00 131.92 ? 1124 HIS A N   1 
ATOM   7902 C CA  . HIS A 1 1165 ? 143.742 140.084 67.736  1.00 131.92 ? 1124 HIS A CA  1 
ATOM   7903 C C   . HIS A 1 1165 ? 142.866 140.496 68.910  1.00 131.92 ? 1124 HIS A C   1 
ATOM   7904 O O   . HIS A 1 1165 ? 141.660 140.233 68.929  1.00 131.92 ? 1124 HIS A O   1 
ATOM   7905 C CB  . HIS A 1 1165 ? 143.823 141.224 66.715  1.00 131.92 ? 1124 HIS A CB  1 
ATOM   7906 C CG  . HIS A 1 1165 ? 144.535 142.438 67.223  1.00 131.92 ? 1124 HIS A CG  1 
ATOM   7907 N ND1 . HIS A 1 1165 ? 143.972 143.695 67.201  1.00 131.92 ? 1124 HIS A ND1 1 
ATOM   7908 C CD2 . HIS A 1 1165 ? 145.768 142.586 67.763  1.00 131.92 ? 1124 HIS A CD2 1 
ATOM   7909 C CE1 . HIS A 1 1165 ? 144.827 144.567 67.706  1.00 131.92 ? 1124 HIS A CE1 1 
ATOM   7910 N NE2 . HIS A 1 1165 ? 145.924 143.919 68.055  1.00 131.92 ? 1124 HIS A NE2 1 
ATOM   7911 N N   . GLU A 1 1166 ? 143.490 141.145 69.897  1.00 132.51 ? 1125 GLU A N   1 
ATOM   7912 C CA  . GLU A 1 1166 ? 142.759 141.551 71.094  1.00 132.51 ? 1125 GLU A CA  1 
ATOM   7913 C C   . GLU A 1 1166 ? 141.661 142.557 70.765  1.00 132.51 ? 1125 GLU A C   1 
ATOM   7914 O O   . GLU A 1 1166 ? 140.539 142.449 71.275  1.00 132.51 ? 1125 GLU A O   1 
ATOM   7915 C CB  . GLU A 1 1166 ? 143.730 142.122 72.129  1.00 132.51 ? 1125 GLU A CB  1 
ATOM   7916 C CG  . GLU A 1 1166 ? 144.664 143.194 71.593  1.00 132.51 ? 1125 GLU A CG  1 
ATOM   7917 C CD  . GLU A 1 1166 ? 145.531 143.806 72.675  1.00 132.51 ? 1125 GLU A CD  1 
ATOM   7918 O OE1 . GLU A 1 1166 ? 145.315 144.988 73.015  1.00 132.51 ? 1125 GLU A OE1 1 
ATOM   7919 O OE2 . GLU A 1 1166 ? 146.431 143.106 73.185  1.00 132.51 ? 1125 GLU A OE2 1 
ATOM   7920 N N   . CYS A 1 1167 ? 141.959 143.536 69.911  1.00 139.52 ? 1126 CYS A N   1 
ATOM   7921 C CA  . CYS A 1 1167 ? 140.990 144.544 69.478  1.00 139.52 ? 1126 CYS A CA  1 
ATOM   7922 C C   . CYS A 1 1167 ? 140.980 144.549 67.950  1.00 139.52 ? 1126 CYS A C   1 
ATOM   7923 O O   . CYS A 1 1167 ? 141.717 145.296 67.301  1.00 139.52 ? 1126 CYS A O   1 
ATOM   7924 C CB  . CYS A 1 1167 ? 141.316 145.917 70.080  1.00 139.52 ? 1126 CYS A CB  1 
ATOM   7925 S SG  . CYS A 1 1167 ? 142.929 146.628 69.657  1.00 139.52 ? 1126 CYS A SG  1 
ATOM   7926 N N   . ALA A 1 1168 ? 140.134 143.696 67.372  1.00 147.86 ? 1127 ALA A N   1 
ATOM   7927 C CA  . ALA A 1 1168 ? 140.104 143.522 65.926  1.00 147.86 ? 1127 ALA A CA  1 
ATOM   7928 C C   . ALA A 1 1168 ? 139.257 144.565 65.214  1.00 147.86 ? 1127 ALA A C   1 
ATOM   7929 O O   . ALA A 1 1168 ? 139.359 144.685 63.988  1.00 147.86 ? 1127 ALA A O   1 
ATOM   7930 C CB  . ALA A 1 1168 ? 139.586 142.125 65.579  1.00 147.86 ? 1127 ALA A CB  1 
ATOM   7931 N N   . THR A 1 1169 ? 138.437 145.321 65.947  1.00 152.42 ? 1128 THR A N   1 
ATOM   7932 C CA  . THR A 1 1169 ? 137.486 146.259 65.354  1.00 152.42 ? 1128 THR A CA  1 
ATOM   7933 C C   . THR A 1 1169 ? 136.644 145.556 64.296  1.00 152.42 ? 1128 THR A C   1 
ATOM   7934 O O   . THR A 1 1169 ? 136.205 144.420 64.500  1.00 152.42 ? 1128 THR A O   1 
ATOM   7935 C CB  . THR A 1 1169 ? 138.201 147.471 64.747  1.00 152.42 ? 1128 THR A CB  1 
ATOM   7936 O OG1 . THR A 1 1169 ? 138.846 147.090 63.527  1.00 152.42 ? 1128 THR A OG1 1 
ATOM   7937 C CG2 . THR A 1 1169 ? 139.235 148.025 65.716  1.00 152.42 ? 1128 THR A CG2 1 
ATOM   7938 N N   . GLU A 1 1170 ? 136.417 146.213 63.174  1.00 153.84 ? 1129 GLU A N   1 
ATOM   7939 C CA  . GLU A 1 1170 ? 135.668 145.583 62.093  1.00 153.84 ? 1129 GLU A CA  1 
ATOM   7940 C C   . GLU A 1 1170 ? 136.406 145.611 60.765  1.00 153.84 ? 1129 GLU A C   1 
ATOM   7941 O O   . GLU A 1 1170 ? 136.347 144.632 60.020  1.00 153.84 ? 1129 GLU A O   1 
ATOM   7942 C CB  . GLU A 1 1170 ? 134.299 146.259 61.935  1.00 153.84 ? 1129 GLU A CB  1 
ATOM   7943 C CG  . GLU A 1 1170 ? 133.439 145.650 60.843  1.00 153.84 ? 1129 GLU A CG  1 
ATOM   7944 C CD  . GLU A 1 1170 ? 133.077 144.208 61.130  1.00 153.84 ? 1129 GLU A CD  1 
ATOM   7945 O OE1 . GLU A 1 1170 ? 132.340 143.964 62.108  1.00 153.84 ? 1129 GLU A OE1 1 
ATOM   7946 O OE2 . GLU A 1 1170 ? 133.532 143.317 60.381  1.00 153.84 ? 1129 GLU A OE2 1 
ATOM   7947 N N   . ALA A 1 1171 ? 137.109 146.701 60.455  1.00 156.24 ? 1130 ALA A N   1 
ATOM   7948 C CA  . ALA A 1 1171 ? 137.799 146.791 59.174  1.00 156.24 ? 1130 ALA A CA  1 
ATOM   7949 C C   . ALA A 1 1171 ? 138.961 145.809 59.094  1.00 156.24 ? 1130 ALA A C   1 
ATOM   7950 O O   . ALA A 1 1171 ? 139.237 145.251 58.023  1.00 156.24 ? 1130 ALA A O   1 
ATOM   7951 C CB  . ALA A 1 1171 ? 138.288 148.219 58.941  1.00 156.24 ? 1130 ALA A CB  1 
ATOM   7952 N N   . GLU A 1 1172 ? 139.663 145.597 60.211  1.00 154.00 ? 1131 GLU A N   1 
ATOM   7953 C CA  . GLU A 1 1172 ? 140.851 144.748 60.184  1.00 154.00 ? 1131 GLU A CA  1 
ATOM   7954 C C   . GLU A 1 1172 ? 140.507 143.333 59.744  1.00 154.00 ? 1131 GLU A C   1 
ATOM   7955 O O   . GLU A 1 1172 ? 141.190 142.757 58.889  1.00 154.00 ? 1131 GLU A O   1 
ATOM   7956 C CB  . GLU A 1 1172 ? 141.519 144.738 61.558  1.00 154.00 ? 1131 GLU A CB  1 
ATOM   7957 C CG  . GLU A 1 1172 ? 141.688 146.117 62.179  1.00 154.00 ? 1131 GLU A CG  1 
ATOM   7958 C CD  . GLU A 1 1172 ? 142.289 146.063 63.571  1.00 154.00 ? 1131 GLU A CD  1 
ATOM   7959 O OE1 . GLU A 1 1172 ? 142.655 144.957 64.021  1.00 154.00 ? 1131 GLU A OE1 1 
ATOM   7960 O OE2 . GLU A 1 1172 ? 142.388 147.125 64.219  1.00 154.00 ? 1131 GLU A OE2 1 
ATOM   7961 N N   . ILE A 1 1173 ? 139.433 142.762 60.292  1.00 153.17 ? 1132 ILE A N   1 
ATOM   7962 C CA  . ILE A 1 1173 ? 139.049 141.420 59.872  1.00 153.17 ? 1132 ILE A CA  1 
ATOM   7963 C C   . ILE A 1 1173 ? 138.476 141.441 58.463  1.00 153.17 ? 1132 ILE A C   1 
ATOM   7964 O O   . ILE A 1 1173 ? 138.513 140.425 57.762  1.00 153.17 ? 1132 ILE A O   1 
ATOM   7965 C CB  . ILE A 1 1173 ? 138.065 140.790 60.869  1.00 153.17 ? 1132 ILE A CB  1 
ATOM   7966 C CG1 . ILE A 1 1173 ? 136.771 141.591 60.923  1.00 153.17 ? 1132 ILE A CG1 1 
ATOM   7967 C CG2 . ILE A 1 1173 ? 138.690 140.698 62.252  1.00 153.17 ? 1132 ILE A CG2 1 
ATOM   7968 C CD1 . ILE A 1 1173 ? 135.699 140.897 61.684  1.00 153.17 ? 1132 ILE A CD1 1 
ATOM   7969 N N   . ILE A 1 1174 ? 137.947 142.582 58.015  1.00 157.22 ? 1133 ILE A N   1 
ATOM   7970 C CA  . ILE A 1 1174 ? 137.497 142.687 56.628  1.00 157.22 ? 1133 ILE A CA  1 
ATOM   7971 C C   . ILE A 1 1174 ? 138.675 142.518 55.678  1.00 157.22 ? 1133 ILE A C   1 
ATOM   7972 O O   . ILE A 1 1174 ? 138.625 141.721 54.730  1.00 157.22 ? 1133 ILE A O   1 
ATOM   7973 C CB  . ILE A 1 1174 ? 136.767 144.022 56.394  1.00 157.22 ? 1133 ILE A CB  1 
ATOM   7974 C CG1 . ILE A 1 1174 ? 135.432 144.043 57.140  1.00 157.22 ? 1133 ILE A CG1 1 
ATOM   7975 C CG2 . ILE A 1 1174 ? 136.549 144.258 54.908  1.00 157.22 ? 1133 ILE A CG2 1 
ATOM   7976 C CD1 . ILE A 1 1174 ? 134.443 143.019 56.647  1.00 157.22 ? 1133 ILE A CD1 1 
ATOM   7977 N N   . GLN A 1 1175 ? 139.762 143.257 55.922  1.00 157.67 ? 1134 GLN A N   1 
ATOM   7978 C CA  . GLN A 1 1175 ? 140.957 143.066 55.103  1.00 157.67 ? 1134 GLN A CA  1 
ATOM   7979 C C   . GLN A 1 1175 ? 141.545 141.674 55.289  1.00 157.67 ? 1134 GLN A C   1 
ATOM   7980 O O   . GLN A 1 1175 ? 142.075 141.088 54.340  1.00 157.67 ? 1134 GLN A O   1 
ATOM   7981 C CB  . GLN A 1 1175 ? 142.010 144.140 55.385  1.00 157.67 ? 1134 GLN A CB  1 
ATOM   7982 C CG  . GLN A 1 1175 ? 141.680 145.519 54.826  1.00 157.67 ? 1134 GLN A CG  1 
ATOM   7983 C CD  . GLN A 1 1175 ? 140.532 146.197 55.526  1.00 157.67 ? 1134 GLN A CD  1 
ATOM   7984 O OE1 . GLN A 1 1175 ? 139.510 146.510 54.915  1.00 157.67 ? 1134 GLN A OE1 1 
ATOM   7985 N NE2 . GLN A 1 1175 ? 140.706 146.465 56.811  1.00 157.67 ? 1134 GLN A NE2 1 
ATOM   7986 N N   . ALA A 1 1176 ? 141.463 141.122 56.501  1.00 154.29 ? 1135 ALA A N   1 
ATOM   7987 C CA  . ALA A 1 1176 ? 141.961 139.767 56.707  1.00 154.29 ? 1135 ALA A CA  1 
ATOM   7988 C C   . ALA A 1 1176 ? 141.202 138.767 55.842  1.00 154.29 ? 1135 ALA A C   1 
ATOM   7989 O O   . ALA A 1 1176 ? 141.808 137.887 55.221  1.00 154.29 ? 1135 ALA A O   1 
ATOM   7990 C CB  . ALA A 1 1176 ? 141.860 139.386 58.181  1.00 154.29 ? 1135 ALA A CB  1 
ATOM   7991 N N   . ALA A 1 1177 ? 139.879 138.901 55.776  1.00 156.50 ? 1136 ALA A N   1 
ATOM   7992 C CA  . ALA A 1 1177 ? 139.077 138.005 54.952  1.00 156.50 ? 1136 ALA A CA  1 
ATOM   7993 C C   . ALA A 1 1177 ? 139.338 138.231 53.469  1.00 156.50 ? 1136 ALA A C   1 
ATOM   7994 O O   . ALA A 1 1177 ? 139.340 137.276 52.683  1.00 156.50 ? 1136 ALA A O   1 
ATOM   7995 C CB  . ALA A 1 1177 ? 137.594 138.184 55.270  1.00 156.50 ? 1136 ALA A CB  1 
ATOM   7996 N N   . THR A 1 1178 ? 139.545 139.487 53.059  1.00 156.05 ? 1137 THR A N   1 
ATOM   7997 C CA  . THR A 1 1178 ? 139.794 139.754 51.645  1.00 156.05 ? 1137 THR A CA  1 
ATOM   7998 C C   . THR A 1 1178 ? 141.132 139.176 51.198  1.00 156.05 ? 1137 THR A C   1 
ATOM   7999 O O   . THR A 1 1178 ? 141.203 138.456 50.195  1.00 156.05 ? 1137 THR A O   1 
ATOM   8000 C CB  . THR A 1 1178 ? 139.744 141.257 51.364  1.00 156.05 ? 1137 THR A CB  1 
ATOM   8001 O OG1 . THR A 1 1178 ? 140.632 141.943 52.252  1.00 156.05 ? 1137 THR A OG1 1 
ATOM   8002 C CG2 . THR A 1 1178 ? 138.330 141.791 51.544  1.00 156.05 ? 1137 THR A CG2 1 
ATOM   8003 N N   . LEU A 1 1179 ? 142.209 139.475 51.933  1.00 155.37 ? 1138 LEU A N   1 
ATOM   8004 C CA  . LEU A 1 1179 ? 143.519 138.935 51.576  1.00 155.37 ? 1138 LEU A CA  1 
ATOM   8005 C C   . LEU A 1 1179 ? 143.556 137.419 51.717  1.00 155.37 ? 1138 LEU A C   1 
ATOM   8006 O O   . LEU A 1 1179 ? 144.143 136.727 50.877  1.00 155.37 ? 1138 LEU A O   1 
ATOM   8007 C CB  . LEU A 1 1179 ? 144.622 139.586 52.413  1.00 155.37 ? 1138 LEU A CB  1 
ATOM   8008 C CG  . LEU A 1 1179 ? 145.099 140.996 52.029  1.00 155.37 ? 1138 LEU A CG  1 
ATOM   8009 C CD1 . LEU A 1 1179 ? 144.095 142.095 52.328  1.00 155.37 ? 1138 LEU A CD1 1 
ATOM   8010 C CD2 . LEU A 1 1179 ? 146.428 141.296 52.708  1.00 155.37 ? 1138 LEU A CD2 1 
ATOM   8011 N N   . ALA A 1 1180 ? 142.936 136.882 52.762  1.00 155.72 ? 1139 ALA A N   1 
ATOM   8012 C CA  . ALA A 1 1180 ? 142.861 135.438 52.927  1.00 155.72 ? 1139 ALA A CA  1 
ATOM   8013 C C   . ALA A 1 1180 ? 141.863 134.790 51.979  1.00 155.72 ? 1139 ALA A C   1 
ATOM   8014 O O   . ALA A 1 1180 ? 141.814 133.559 51.911  1.00 155.72 ? 1139 ALA A O   1 
ATOM   8015 C CB  . ALA A 1 1180 ? 142.497 135.091 54.372  1.00 155.72 ? 1139 ALA A CB  1 
ATOM   8016 N N   . SER A 1 1181 ? 141.074 135.588 51.256  1.00 157.10 ? 1140 SER A N   1 
ATOM   8017 C CA  . SER A 1 1181 ? 140.041 135.110 50.340  1.00 157.10 ? 1140 SER A CA  1 
ATOM   8018 C C   . SER A 1 1181 ? 138.960 134.310 51.057  1.00 157.10 ? 1140 SER A C   1 
ATOM   8019 O O   . SER A 1 1181 ? 138.266 133.501 50.434  1.00 157.10 ? 1140 SER A O   1 
ATOM   8020 C CB  . SER A 1 1181 ? 140.641 134.284 49.195  1.00 157.10 ? 1140 SER A CB  1 
ATOM   8021 O OG  . SER A 1 1181 ? 140.974 132.979 49.629  1.00 157.10 ? 1140 SER A OG  1 
ATOM   8022 N N   . ALA A 1 1182 ? 138.804 134.523 52.365  1.00 159.72 ? 1141 ALA A N   1 
ATOM   8023 C CA  . ALA A 1 1182 ? 137.756 133.832 53.105  1.00 159.72 ? 1141 ALA A CA  1 
ATOM   8024 C C   . ALA A 1 1182 ? 136.381 134.407 52.799  1.00 159.72 ? 1141 ALA A C   1 
ATOM   8025 O O   . ALA A 1 1182 ? 135.374 133.703 52.924  1.00 159.72 ? 1141 ALA A O   1 
ATOM   8026 C CB  . ALA A 1 1182 ? 138.038 133.898 54.605  1.00 159.72 ? 1141 ALA A CB  1 
ATOM   8027 N N   . HIS A 1 1183 ? 136.316 135.678 52.397  1.00 160.68 ? 1142 HIS A N   1 
ATOM   8028 C CA  . HIS A 1 1183 ? 135.034 136.303 52.099  1.00 160.68 ? 1142 HIS A CA  1 
ATOM   8029 C C   . HIS A 1 1183 ? 134.322 135.622 50.938  1.00 160.68 ? 1142 HIS A C   1 
ATOM   8030 O O   . HIS A 1 1183 ? 133.092 135.711 50.844  1.00 160.68 ? 1142 HIS A O   1 
ATOM   8031 C CB  . HIS A 1 1183 ? 135.243 137.788 51.794  1.00 160.68 ? 1142 HIS A CB  1 
ATOM   8032 C CG  . HIS A 1 1183 ? 133.977 138.586 51.749  1.00 160.68 ? 1142 HIS A CG  1 
ATOM   8033 N ND1 . HIS A 1 1183 ? 133.921 139.858 51.220  1.00 160.68 ? 1142 HIS A ND1 1 
ATOM   8034 C CD2 . HIS A 1 1183 ? 132.727 138.303 52.181  1.00 160.68 ? 1142 HIS A CD2 1 
ATOM   8035 C CE1 . HIS A 1 1183 ? 132.687 140.319 51.320  1.00 160.68 ? 1142 HIS A CE1 1 
ATOM   8036 N NE2 . HIS A 1 1183 ? 131.943 139.395 51.899  1.00 160.68 ? 1142 HIS A NE2 1 
ATOM   8037 N N   . LYS A 1 1184 ? 135.064 134.917 50.078  1.00 160.71 ? 1143 LYS A N   1 
ATOM   8038 C CA  . LYS A 1 1184 ? 134.482 134.341 48.869  1.00 160.71 ? 1143 LYS A CA  1 
ATOM   8039 C C   . LYS A 1 1184 ? 133.299 133.438 49.194  1.00 160.71 ? 1143 LYS A C   1 
ATOM   8040 O O   . LYS A 1 1184 ? 132.242 133.532 48.559  1.00 160.71 ? 1143 LYS A O   1 
ATOM   8041 C CB  . LYS A 1 1184 ? 135.549 133.574 48.088  1.00 160.71 ? 1143 LYS A CB  1 
ATOM   8042 C CG  . LYS A 1 1184 ? 136.251 134.395 47.013  1.00 160.71 ? 1143 LYS A CG  1 
ATOM   8043 C CD  . LYS A 1 1184 ? 137.148 135.469 47.611  1.00 160.71 ? 1143 LYS A CD  1 
ATOM   8044 C CE  . LYS A 1 1184 ? 137.926 136.199 46.528  1.00 160.71 ? 1143 LYS A CE  1 
ATOM   8045 N NZ  . LYS A 1 1184 ? 138.869 137.203 47.097  1.00 160.71 ? 1143 LYS A NZ  1 
ATOM   8046 N N   . PHE A 1 1185 ? 133.451 132.556 50.180  1.00 161.20 ? 1144 PHE A N   1 
ATOM   8047 C CA  . PHE A 1 1185 ? 132.310 131.757 50.604  1.00 161.20 ? 1144 PHE A CA  1 
ATOM   8048 C C   . PHE A 1 1185 ? 131.474 132.458 51.662  1.00 161.20 ? 1144 PHE A C   1 
ATOM   8049 O O   . PHE A 1 1185 ? 130.300 132.111 51.832  1.00 161.20 ? 1144 PHE A O   1 
ATOM   8050 C CB  . PHE A 1 1185 ? 132.760 130.389 51.138  1.00 161.20 ? 1144 PHE A CB  1 
ATOM   8051 C CG  . PHE A 1 1185 ? 133.948 130.441 52.058  1.00 161.20 ? 1144 PHE A CG  1 
ATOM   8052 C CD1 . PHE A 1 1185 ? 133.835 130.980 53.329  1.00 161.20 ? 1144 PHE A CD1 1 
ATOM   8053 C CD2 . PHE A 1 1185 ? 135.176 129.948 51.655  1.00 161.20 ? 1144 PHE A CD2 1 
ATOM   8054 C CE1 . PHE A 1 1185 ? 134.920 131.018 54.181  1.00 161.20 ? 1144 PHE A CE1 1 
ATOM   8055 C CE2 . PHE A 1 1185 ? 136.266 129.986 52.506  1.00 161.20 ? 1144 PHE A CE2 1 
ATOM   8056 C CZ  . PHE A 1 1185 ? 136.138 130.526 53.767  1.00 161.20 ? 1144 PHE A CZ  1 
ATOM   8057 N N   . ILE A 1 1186 ? 132.047 133.438 52.365  1.00 163.50 ? 1145 ILE A N   1 
ATOM   8058 C CA  . ILE A 1 1186 ? 131.316 134.115 53.433  1.00 163.50 ? 1145 ILE A CA  1 
ATOM   8059 C C   . ILE A 1 1186 ? 130.112 134.852 52.864  1.00 163.50 ? 1145 ILE A C   1 
ATOM   8060 O O   . ILE A 1 1186 ? 129.007 134.787 53.416  1.00 163.50 ? 1145 ILE A O   1 
ATOM   8061 C CB  . ILE A 1 1186 ? 132.254 135.059 54.207  1.00 163.50 ? 1145 ILE A CB  1 
ATOM   8062 C CG1 . ILE A 1 1186 ? 133.071 134.267 55.228  1.00 163.50 ? 1145 ILE A CG1 1 
ATOM   8063 C CG2 . ILE A 1 1186 ? 131.462 136.156 54.897  1.00 163.50 ? 1145 ILE A CG2 1 
ATOM   8064 C CD1 . ILE A 1 1186 ? 134.261 135.016 55.775  1.00 163.50 ? 1145 ILE A CD1 1 
ATOM   8065 N N   . SER A 1 1187 ? 130.305 135.558 51.750  1.00 166.52 ? 1146 SER A N   1 
ATOM   8066 C CA  . SER A 1 1187 ? 129.166 136.138 51.048  1.00 166.52 ? 1146 SER A CA  1 
ATOM   8067 C C   . SER A 1 1187 ? 128.213 135.048 50.575  1.00 166.52 ? 1146 SER A C   1 
ATOM   8068 O O   . SER A 1 1187 ? 126.989 135.230 50.593  1.00 166.52 ? 1146 SER A O   1 
ATOM   8069 C CB  . SER A 1 1187 ? 129.650 136.983 49.871  1.00 166.52 ? 1146 SER A CB  1 
ATOM   8070 O OG  . SER A 1 1187 ? 130.383 136.197 48.948  1.00 166.52 ? 1146 SER A OG  1 
ATOM   8071 N N   . ALA A 1 1188 ? 128.757 133.904 50.151  1.00 166.76 ? 1147 ALA A N   1 
ATOM   8072 C CA  . ALA A 1 1188 ? 127.912 132.779 49.767  1.00 166.76 ? 1147 ALA A CA  1 
ATOM   8073 C C   . ALA A 1 1188 ? 127.169 132.199 50.963  1.00 166.76 ? 1147 ALA A C   1 
ATOM   8074 O O   . ALA A 1 1188 ? 126.092 131.616 50.797  1.00 166.76 ? 1147 ALA A O   1 
ATOM   8075 C CB  . ALA A 1 1188 ? 128.754 131.696 49.091  1.00 166.76 ? 1147 ALA A CB  1 
ATOM   8076 N N   . LEU A 1 1189 ? 127.725 132.336 52.163  1.00 165.81 ? 1148 LEU A N   1 
ATOM   8077 C CA  . LEU A 1 1189 ? 127.041 131.863 53.353  1.00 165.81 ? 1148 LEU A CA  1 
ATOM   8078 C C   . LEU A 1 1189 ? 125.785 132.695 53.603  1.00 165.81 ? 1148 LEU A C   1 
ATOM   8079 O O   . LEU A 1 1189 ? 125.774 133.906 53.361  1.00 165.81 ? 1148 LEU A O   1 
ATOM   8080 C CB  . LEU A 1 1189 ? 127.963 131.932 54.568  1.00 165.81 ? 1148 LEU A CB  1 
ATOM   8081 C CG  . LEU A 1 1189 ? 129.151 130.967 54.567  1.00 165.81 ? 1148 LEU A CG  1 
ATOM   8082 C CD1 . LEU A 1 1189 ? 129.898 131.024 55.888  1.00 165.81 ? 1148 LEU A CD1 1 
ATOM   8083 C CD2 . LEU A 1 1189 ? 128.690 129.549 54.265  1.00 165.81 ? 1148 LEU A CD2 1 
ATOM   8084 N N   . PRO A 1 1190 ? 124.706 132.066 54.078  1.00 166.11 ? 1149 PRO A N   1 
ATOM   8085 C CA  . PRO A 1 1190 ? 123.461 132.810 54.321  1.00 166.11 ? 1149 PRO A CA  1 
ATOM   8086 C C   . PRO A 1 1190 ? 123.625 133.905 55.362  1.00 166.11 ? 1149 PRO A C   1 
ATOM   8087 O O   . PRO A 1 1190 ? 123.334 135.074 55.093  1.00 166.11 ? 1149 PRO A O   1 
ATOM   8088 C CB  . PRO A 1 1190 ? 122.489 131.722 54.801  1.00 166.11 ? 1149 PRO A CB  1 
ATOM   8089 C CG  . PRO A 1 1190 ? 123.064 130.439 54.289  1.00 166.11 ? 1149 PRO A CG  1 
ATOM   8090 C CD  . PRO A 1 1190 ? 124.549 130.623 54.326  1.00 166.11 ? 1149 PRO A CD  1 
ATOM   8091 N N   . GLU A 1 1191 ? 124.095 133.538 56.553  1.00 164.02 ? 1150 GLU A N   1 
ATOM   8092 C CA  . GLU A 1 1191 ? 124.322 134.518 57.607  1.00 164.02 ? 1150 GLU A CA  1 
ATOM   8093 C C   . GLU A 1 1191 ? 125.642 135.259 57.452  1.00 164.02 ? 1150 GLU A C   1 
ATOM   8094 O O   . GLU A 1 1191 ? 125.829 136.297 58.097  1.00 164.02 ? 1150 GLU A O   1 
ATOM   8095 C CB  . GLU A 1 1191 ? 124.277 133.841 58.978  1.00 164.02 ? 1150 GLU A CB  1 
ATOM   8096 C CG  . GLU A 1 1191 ? 122.985 133.098 59.274  1.00 164.02 ? 1150 GLU A CG  1 
ATOM   8097 C CD  . GLU A 1 1191 ? 123.022 131.658 58.805  1.00 164.02 ? 1150 GLU A CD  1 
ATOM   8098 O OE1 . GLU A 1 1191 ? 124.042 131.250 58.211  1.00 164.02 ? 1150 GLU A OE1 1 
ATOM   8099 O OE2 . GLU A 1 1191 ? 122.031 130.932 59.034  1.00 164.02 ? 1150 GLU A OE2 1 
ATOM   8100 N N   . GLY A 1 1192 ? 126.551 134.760 56.619  1.00 163.21 ? 1151 GLY A N   1 
ATOM   8101 C CA  . GLY A 1 1192 ? 127.843 135.390 56.440  1.00 163.21 ? 1151 GLY A CA  1 
ATOM   8102 C C   . GLY A 1 1192 ? 128.746 135.261 57.648  1.00 163.21 ? 1151 GLY A C   1 
ATOM   8103 O O   . GLY A 1 1192 ? 129.146 134.154 58.019  1.00 163.21 ? 1151 GLY A O   1 
ATOM   8104 N N   . TYR A 1 1193 ? 129.077 136.394 58.271  1.00 157.19 ? 1152 TYR A N   1 
ATOM   8105 C CA  . TYR A 1 1193 ? 129.950 136.367 59.440  1.00 157.19 ? 1152 TYR A CA  1 
ATOM   8106 C C   . TYR A 1 1193 ? 129.279 135.703 60.635  1.00 157.19 ? 1152 TYR A C   1 
ATOM   8107 O O   . TYR A 1 1193 ? 129.943 134.997 61.402  1.00 157.19 ? 1152 TYR A O   1 
ATOM   8108 C CB  . TYR A 1 1193 ? 130.382 137.787 59.803  1.00 157.19 ? 1152 TYR A CB  1 
ATOM   8109 C CG  . TYR A 1 1193 ? 131.482 138.340 58.927  1.00 157.19 ? 1152 TYR A CG  1 
ATOM   8110 C CD1 . TYR A 1 1193 ? 132.239 137.504 58.120  1.00 157.19 ? 1152 TYR A CD1 1 
ATOM   8111 C CD2 . TYR A 1 1193 ? 131.760 139.701 58.904  1.00 157.19 ? 1152 TYR A CD2 1 
ATOM   8112 C CE1 . TYR A 1 1193 ? 133.245 138.003 57.319  1.00 157.19 ? 1152 TYR A CE1 1 
ATOM   8113 C CE2 . TYR A 1 1193 ? 132.766 140.210 58.104  1.00 157.19 ? 1152 TYR A CE2 1 
ATOM   8114 C CZ  . TYR A 1 1193 ? 133.504 139.355 57.313  1.00 157.19 ? 1152 TYR A CZ  1 
ATOM   8115 O OH  . TYR A 1 1193 ? 134.507 139.847 56.511  1.00 157.19 ? 1152 TYR A OH  1 
ATOM   8116 N N   . LYS A 1 1194 ? 127.976 135.907 60.807  1.00 155.45 ? 1153 LYS A N   1 
ATOM   8117 C CA  . LYS A 1 1194 ? 127.275 135.504 62.018  1.00 155.45 ? 1153 LYS A CA  1 
ATOM   8118 C C   . LYS A 1 1194 ? 126.657 134.116 61.918  1.00 155.45 ? 1153 LYS A C   1 
ATOM   8119 O O   . LYS A 1 1194 ? 125.737 133.805 62.681  1.00 155.45 ? 1153 LYS A O   1 
ATOM   8120 C CB  . LYS A 1 1194 ? 126.199 136.533 62.361  1.00 155.45 ? 1153 LYS A CB  1 
ATOM   8121 C CG  . LYS A 1 1194 ? 126.610 137.966 62.071  1.00 155.45 ? 1153 LYS A CG  1 
ATOM   8122 C CD  . LYS A 1 1194 ? 127.421 138.548 63.215  1.00 155.45 ? 1153 LYS A CD  1 
ATOM   8123 C CE  . LYS A 1 1194 ? 127.440 140.067 63.166  1.00 155.45 ? 1153 LYS A CE  1 
ATOM   8124 N NZ  . LYS A 1 1194 ? 128.410 140.579 62.161  1.00 155.45 ? 1153 LYS A NZ  1 
ATOM   8125 N N   . THR A 1 1195 ? 127.130 133.279 61.002  1.00 158.33 ? 1154 THR A N   1 
ATOM   8126 C CA  . THR A 1 1195 ? 126.643 131.908 60.934  1.00 158.33 ? 1154 THR A CA  1 
ATOM   8127 C C   . THR A 1 1195 ? 127.179 131.102 62.111  1.00 158.33 ? 1154 THR A C   1 
ATOM   8128 O O   . THR A 1 1195 ? 128.329 131.276 62.527  1.00 158.33 ? 1154 THR A O   1 
ATOM   8129 C CB  . THR A 1 1195 ? 127.049 131.258 59.611  1.00 158.33 ? 1154 THR A CB  1 
ATOM   8130 O OG1 . THR A 1 1195 ? 126.628 129.889 59.597  1.00 158.33 ? 1154 THR A OG1 1 
ATOM   8131 C CG2 . THR A 1 1195 ? 128.552 131.327 59.410  1.00 158.33 ? 1154 THR A CG2 1 
ATOM   8132 N N   . TYR A 1 1196 ? 126.340 130.231 62.661  1.00 160.14 ? 1155 TYR A N   1 
ATOM   8133 C CA  . TYR A 1 1196 ? 126.759 129.389 63.773  1.00 160.14 ? 1155 TYR A CA  1 
ATOM   8134 C C   . TYR A 1 1196 ? 127.599 128.233 63.243  1.00 160.14 ? 1155 TYR A C   1 
ATOM   8135 O O   . TYR A 1 1196 ? 127.088 127.354 62.541  1.00 160.14 ? 1155 TYR A O   1 
ATOM   8136 C CB  . TYR A 1 1196 ? 125.539 128.879 64.540  1.00 160.14 ? 1155 TYR A CB  1 
ATOM   8137 C CG  . TYR A 1 1196 ? 125.844 127.825 65.584  1.00 160.14 ? 1155 TYR A CG  1 
ATOM   8138 C CD1 . TYR A 1 1196 ? 126.949 127.941 66.414  1.00 160.14 ? 1155 TYR A CD1 1 
ATOM   8139 C CD2 . TYR A 1 1196 ? 125.005 126.734 65.764  1.00 160.14 ? 1155 TYR A CD2 1 
ATOM   8140 C CE1 . TYR A 1 1196 ? 127.230 126.992 67.374  1.00 160.14 ? 1155 TYR A CE1 1 
ATOM   8141 C CE2 . TYR A 1 1196 ? 125.277 125.776 66.724  1.00 160.14 ? 1155 TYR A CE2 1 
ATOM   8142 C CZ  . TYR A 1 1196 ? 126.392 125.912 67.526  1.00 160.14 ? 1155 TYR A CZ  1 
ATOM   8143 O OH  . TYR A 1 1196 ? 126.673 124.968 68.487  1.00 160.14 ? 1155 TYR A OH  1 
ATOM   8144 N N   . VAL A 1 1197 ? 128.885 128.237 63.579  1.00 157.90 ? 1156 VAL A N   1 
ATOM   8145 C CA  . VAL A 1 1197 ? 129.840 127.263 63.067  1.00 157.90 ? 1156 VAL A CA  1 
ATOM   8146 C C   . VAL A 1 1197 ? 130.444 126.498 64.235  1.00 157.90 ? 1156 VAL A C   1 
ATOM   8147 O O   . VAL A 1 1197 ? 130.784 127.083 65.269  1.00 157.90 ? 1156 VAL A O   1 
ATOM   8148 C CB  . VAL A 1 1197 ? 130.938 127.937 62.216  1.00 157.90 ? 1156 VAL A CB  1 
ATOM   8149 C CG1 . VAL A 1 1197 ? 130.325 128.570 60.985  1.00 157.90 ? 1156 VAL A CG1 1 
ATOM   8150 C CG2 . VAL A 1 1197 ? 131.679 128.990 63.023  1.00 157.90 ? 1156 VAL A CG2 1 
ATOM   8151 N N   . GLY A 1 1198 ? 130.552 125.188 64.078  1.00 167.67 ? 1157 GLY A N   1 
ATOM   8152 C CA  . GLY A 1 1198 ? 131.093 124.345 65.132  1.00 167.67 ? 1157 GLY A CA  1 
ATOM   8153 C C   . GLY A 1 1198 ? 130.549 122.930 65.013  1.00 167.67 ? 1157 GLY A C   1 
ATOM   8154 O O   . GLY A 1 1198 ? 130.193 122.480 63.924  1.00 167.67 ? 1157 GLY A O   1 
ATOM   8155 N N   . GLU A 1 1199 ? 130.501 122.249 66.159  1.00 174.50 ? 1158 GLU A N   1 
ATOM   8156 C CA  . GLU A 1 1199 ? 129.990 120.882 66.186  1.00 174.50 ? 1158 GLU A CA  1 
ATOM   8157 C C   . GLU A 1 1199 ? 128.510 120.842 65.826  1.00 174.50 ? 1158 GLU A C   1 
ATOM   8158 O O   . GLU A 1 1199 ? 128.091 120.072 64.954  1.00 174.50 ? 1158 GLU A O   1 
ATOM   8159 C CB  . GLU A 1 1199 ? 130.225 120.264 67.565  1.00 174.50 ? 1158 GLU A CB  1 
ATOM   8160 C CG  . GLU A 1 1199 ? 131.664 120.343 68.050  1.00 174.50 ? 1158 GLU A CG  1 
ATOM   8161 C CD  . GLU A 1 1199 ? 131.807 119.955 69.509  1.00 174.50 ? 1158 GLU A CD  1 
ATOM   8162 O OE1 . GLU A 1 1199 ? 130.781 119.638 70.145  1.00 174.50 ? 1158 GLU A OE1 1 
ATOM   8163 O OE2 . GLU A 1 1199 ? 132.946 119.967 70.021  1.00 174.50 ? 1158 GLU A OE2 1 
ATOM   8164 N N   . ARG A 1 1200 ? 127.702 121.675 66.481  1.00 170.85 ? 1159 ARG A N   1 
ATOM   8165 C CA  . ARG A 1 1200 ? 126.261 121.665 66.270  1.00 170.85 ? 1159 ARG A CA  1 
ATOM   8166 C C   . ARG A 1 1200 ? 125.825 122.509 65.081  1.00 170.85 ? 1159 ARG A C   1 
ATOM   8167 O O   . ARG A 1 1200 ? 124.757 122.249 64.514  1.00 170.85 ? 1159 ARG A O   1 
ATOM   8168 C CB  . ARG A 1 1200 ? 125.541 122.162 67.528  1.00 170.85 ? 1159 ARG A CB  1 
ATOM   8169 C CG  . ARG A 1 1200 ? 124.068 121.792 67.587  1.00 170.85 ? 1159 ARG A CG  1 
ATOM   8170 C CD  . ARG A 1 1200 ? 123.409 122.307 68.856  1.00 170.85 ? 1159 ARG A CD  1 
ATOM   8171 N NE  . ARG A 1 1200 ? 123.361 123.764 68.894  1.00 170.85 ? 1159 ARG A NE  1 
ATOM   8172 C CZ  . ARG A 1 1200 ? 123.840 124.506 69.883  1.00 170.85 ? 1159 ARG A CZ  1 
ATOM   8173 N NH1 . ARG A 1 1200 ? 124.411 123.960 70.944  1.00 170.85 ? 1159 ARG A NH1 1 
ATOM   8174 N NH2 . ARG A 1 1200 ? 123.739 125.831 69.807  1.00 170.85 ? 1159 ARG A NH2 1 
ATOM   8175 N N   . GLY A 1 1201 ? 126.618 123.498 64.687  1.00 170.47 ? 1160 GLY A N   1 
ATOM   8176 C CA  . GLY A 1 1201 ? 126.243 124.401 63.622  1.00 170.47 ? 1160 GLY A CA  1 
ATOM   8177 C C   . GLY A 1 1201 ? 126.630 123.884 62.252  1.00 170.47 ? 1160 GLY A C   1 
ATOM   8178 O O   . GLY A 1 1201 ? 126.928 122.707 62.046  1.00 170.47 ? 1160 GLY A O   1 
ATOM   8179 N N   . VAL A 1 1202 ? 126.611 124.804 61.288  1.00 167.70 ? 1161 VAL A N   1 
ATOM   8180 C CA  . VAL A 1 1202 ? 126.976 124.493 59.912  1.00 167.70 ? 1161 VAL A CA  1 
ATOM   8181 C C   . VAL A 1 1202 ? 128.447 124.106 59.872  1.00 167.70 ? 1161 VAL A C   1 
ATOM   8182 O O   . VAL A 1 1202 ? 129.328 124.941 60.105  1.00 167.70 ? 1161 VAL A O   1 
ATOM   8183 C CB  . VAL A 1 1202 ? 126.691 125.681 58.976  1.00 167.70 ? 1161 VAL A CB  1 
ATOM   8184 C CG1 . VAL A 1 1202 ? 127.071 125.334 57.545  1.00 167.70 ? 1161 VAL A CG1 1 
ATOM   8185 C CG2 . VAL A 1 1202 ? 125.229 126.089 59.065  1.00 167.70 ? 1161 VAL A CG2 1 
ATOM   8186 N N   . GLN A 1 1203 ? 128.722 122.839 59.576  1.00 166.32 ? 1162 GLN A N   1 
ATOM   8187 C CA  . GLN A 1 1203 ? 130.092 122.343 59.538  1.00 166.32 ? 1162 GLN A CA  1 
ATOM   8188 C C   . GLN A 1 1203 ? 130.697 122.671 58.181  1.00 166.32 ? 1162 GLN A C   1 
ATOM   8189 O O   . GLN A 1 1203 ? 130.333 122.067 57.166  1.00 166.32 ? 1162 GLN A O   1 
ATOM   8190 C CB  . GLN A 1 1203 ? 130.127 120.843 59.815  1.00 166.32 ? 1162 GLN A CB  1 
ATOM   8191 C CG  . GLN A 1 1203 ? 129.701 120.469 61.222  1.00 166.32 ? 1162 GLN A CG  1 
ATOM   8192 C CD  . GLN A 1 1203 ? 129.913 119.001 61.519  1.00 166.32 ? 1162 GLN A CD  1 
ATOM   8193 O OE1 . GLN A 1 1203 ? 130.339 118.236 60.653  1.00 166.32 ? 1162 GLN A OE1 1 
ATOM   8194 N NE2 . GLN A 1 1203 ? 129.620 118.597 62.750  1.00 166.32 ? 1162 GLN A NE2 1 
ATOM   8195 N N   . LEU A 1 1204 ? 131.620 123.626 58.161  1.00 160.09 ? 1163 LEU A N   1 
ATOM   8196 C CA  . LEU A 1 1204 ? 132.244 124.039 56.917  1.00 160.09 ? 1163 LEU A CA  1 
ATOM   8197 C C   . LEU A 1 1204 ? 133.217 122.972 56.428  1.00 160.09 ? 1163 LEU A C   1 
ATOM   8198 O O   . LEU A 1 1204 ? 133.623 122.072 57.168  1.00 160.09 ? 1163 LEU A O   1 
ATOM   8199 C CB  . LEU A 1 1204 ? 132.971 125.372 57.101  1.00 160.09 ? 1163 LEU A CB  1 
ATOM   8200 C CG  . LEU A 1 1204 ? 132.159 126.649 56.873  1.00 160.09 ? 1163 LEU A CG  1 
ATOM   8201 C CD1 . LEU A 1 1204 ? 131.024 126.773 57.874  1.00 160.09 ? 1163 LEU A CD1 1 
ATOM   8202 C CD2 . LEU A 1 1204 ? 133.062 127.872 56.935  1.00 160.09 ? 1163 LEU A CD2 1 
ATOM   8203 N N   . SER A 1 1205 ? 133.585 123.079 55.154  1.00 158.46 ? 1164 SER A N   1 
ATOM   8204 C CA  . SER A 1 1205 ? 134.557 122.166 54.582  1.00 158.46 ? 1164 SER A CA  1 
ATOM   8205 C C   . SER A 1 1205 ? 135.935 122.411 55.190  1.00 158.46 ? 1164 SER A C   1 
ATOM   8206 O O   . SER A 1 1205 ? 136.222 123.481 55.733  1.00 158.46 ? 1164 SER A O   1 
ATOM   8207 C CB  . SER A 1 1205 ? 134.616 122.324 53.064  1.00 158.46 ? 1164 SER A CB  1 
ATOM   8208 O OG  . SER A 1 1205 ? 135.171 123.578 52.707  1.00 158.46 ? 1164 SER A OG  1 
ATOM   8209 N N   . GLY A 1 1206 ? 136.791 121.391 55.099  1.00 156.56 ? 1165 GLY A N   1 
ATOM   8210 C CA  . GLY A 1 1206 ? 138.128 121.513 55.657  1.00 156.56 ? 1165 GLY A CA  1 
ATOM   8211 C C   . GLY A 1 1206 ? 138.901 122.676 55.069  1.00 156.56 ? 1165 GLY A C   1 
ATOM   8212 O O   . GLY A 1 1206 ? 139.610 123.390 55.784  1.00 156.56 ? 1165 GLY A O   1 
ATOM   8213 N N   . GLY A 1 1207 ? 138.766 122.892 53.759  1.00 157.71 ? 1166 GLY A N   1 
ATOM   8214 C CA  . GLY A 1 1207 ? 139.419 124.032 53.140  1.00 157.71 ? 1166 GLY A CA  1 
ATOM   8215 C C   . GLY A 1 1207 ? 138.914 125.355 53.679  1.00 157.71 ? 1166 GLY A C   1 
ATOM   8216 O O   . GLY A 1 1207 ? 139.699 126.269 53.944  1.00 157.71 ? 1166 GLY A O   1 
ATOM   8217 N N   . GLN A 1 1208 ? 137.598 125.475 53.858  1.00 156.53 ? 1167 GLN A N   1 
ATOM   8218 C CA  . GLN A 1 1208 ? 137.032 126.707 54.398  1.00 156.53 ? 1167 GLN A CA  1 
ATOM   8219 C C   . GLN A 1 1208 ? 137.478 126.937 55.837  1.00 156.53 ? 1167 GLN A C   1 
ATOM   8220 O O   . GLN A 1 1208 ? 137.789 128.070 56.225  1.00 156.53 ? 1167 GLN A O   1 
ATOM   8221 C CB  . GLN A 1 1208 ? 135.508 126.660 54.296  1.00 156.53 ? 1167 GLN A CB  1 
ATOM   8222 C CG  . GLN A 1 1208 ? 135.003 126.743 52.863  1.00 156.53 ? 1167 GLN A CG  1 
ATOM   8223 C CD  . GLN A 1 1208 ? 133.494 126.756 52.762  1.00 156.53 ? 1167 GLN A CD  1 
ATOM   8224 O OE1 . GLN A 1 1208 ? 132.791 126.665 53.767  1.00 156.53 ? 1167 GLN A OE1 1 
ATOM   8225 N NE2 . GLN A 1 1208 ? 132.984 126.876 51.543  1.00 156.53 ? 1167 GLN A NE2 1 
ATOM   8226 N N   . LYS A 1 1209 ? 137.520 125.873 56.643  1.00 152.30 ? 1168 LYS A N   1 
ATOM   8227 C CA  . LYS A 1 1209 ? 137.984 126.001 58.021  1.00 152.30 ? 1168 LYS A CA  1 
ATOM   8228 C C   . LYS A 1 1209 ? 139.443 126.435 58.070  1.00 152.30 ? 1168 LYS A C   1 
ATOM   8229 O O   . LYS A 1 1209 ? 139.818 127.319 58.849  1.00 152.30 ? 1168 LYS A O   1 
ATOM   8230 C CB  . LYS A 1 1209 ? 137.790 124.677 58.759  1.00 152.30 ? 1168 LYS A CB  1 
ATOM   8231 C CG  . LYS A 1 1209 ? 136.340 124.323 59.026  1.00 152.30 ? 1168 LYS A CG  1 
ATOM   8232 C CD  . LYS A 1 1209 ? 136.201 122.890 59.513  1.00 152.30 ? 1168 LYS A CD  1 
ATOM   8233 C CE  . LYS A 1 1209 ? 137.175 122.587 60.638  1.00 152.30 ? 1168 LYS A CE  1 
ATOM   8234 N NZ  . LYS A 1 1209 ? 137.057 121.180 61.107  1.00 152.30 ? 1168 LYS A NZ  1 
ATOM   8235 N N   . GLN A 1 1210 ? 140.286 125.823 57.235  1.00 155.37 ? 1169 GLN A N   1 
ATOM   8236 C CA  . GLN A 1 1210 ? 141.688 126.221 57.206  1.00 155.37 ? 1169 GLN A CA  1 
ATOM   8237 C C   . GLN A 1 1210 ? 141.848 127.652 56.710  1.00 155.37 ? 1169 GLN A C   1 
ATOM   8238 O O   . GLN A 1 1210 ? 142.710 128.388 57.204  1.00 155.37 ? 1169 GLN A O   1 
ATOM   8239 C CB  . GLN A 1 1210 ? 142.490 125.250 56.342  1.00 155.37 ? 1169 GLN A CB  1 
ATOM   8240 C CG  . GLN A 1 1210 ? 142.571 123.849 56.932  1.00 155.37 ? 1169 GLN A CG  1 
ATOM   8241 C CD  . GLN A 1 1210 ? 143.352 122.887 56.061  1.00 155.37 ? 1169 GLN A CD  1 
ATOM   8242 O OE1 . GLN A 1 1210 ? 143.792 123.236 54.967  1.00 155.37 ? 1169 GLN A OE1 1 
ATOM   8243 N NE2 . GLN A 1 1210 ? 143.525 121.662 56.543  1.00 155.37 ? 1169 GLN A NE2 1 
ATOM   8244 N N   . ARG A 1 1211 ? 141.014 128.073 55.757  1.00 153.93 ? 1170 ARG A N   1 
ATOM   8245 C CA  . ARG A 1 1211 ? 141.115 129.437 55.250  1.00 153.93 ? 1170 ARG A CA  1 
ATOM   8246 C C   . ARG A 1 1211 ? 140.697 130.453 56.305  1.00 153.93 ? 1170 ARG A C   1 
ATOM   8247 O O   . ARG A 1 1211 ? 141.322 131.512 56.432  1.00 153.93 ? 1170 ARG A O   1 
ATOM   8248 C CB  . ARG A 1 1211 ? 140.279 129.590 53.980  1.00 153.93 ? 1170 ARG A CB  1 
ATOM   8249 C CG  . ARG A 1 1211 ? 140.921 130.512 52.959  1.00 153.93 ? 1170 ARG A CG  1 
ATOM   8250 C CD  . ARG A 1 1211 ? 139.935 131.078 51.949  1.00 153.93 ? 1170 ARG A CD  1 
ATOM   8251 N NE  . ARG A 1 1211 ? 139.666 130.151 50.856  1.00 153.93 ? 1170 ARG A NE  1 
ATOM   8252 C CZ  . ARG A 1 1211 ? 138.612 130.222 50.055  1.00 153.93 ? 1170 ARG A CZ  1 
ATOM   8253 N NH1 . ARG A 1 1211 ? 137.746 131.219 50.137  1.00 153.93 ? 1170 ARG A NH1 1 
ATOM   8254 N NH2 . ARG A 1 1211 ? 138.434 129.283 49.131  1.00 153.93 ? 1170 ARG A NH2 1 
ATOM   8255 N N   . ILE A 1 1212 ? 139.653 130.155 57.084  1.00 147.84 ? 1171 ILE A N   1 
ATOM   8256 C CA  . ILE A 1 1212 ? 139.276 131.092 58.140  1.00 147.84 ? 1171 ILE A CA  1 
ATOM   8257 C C   . ILE A 1 1212 ? 140.310 131.087 59.262  1.00 147.84 ? 1171 ILE A C   1 
ATOM   8258 O O   . ILE A 1 1212 ? 140.550 132.123 59.897  1.00 147.84 ? 1171 ILE A O   1 
ATOM   8259 C CB  . ILE A 1 1212 ? 137.854 130.809 58.668  1.00 147.84 ? 1171 ILE A CB  1 
ATOM   8260 C CG1 . ILE A 1 1212 ? 137.796 129.497 59.448  1.00 147.84 ? 1171 ILE A CG1 1 
ATOM   8261 C CG2 . ILE A 1 1212 ? 136.849 130.819 57.526  1.00 147.84 ? 1171 ILE A CG2 1 
ATOM   8262 C CD1 . ILE A 1 1212 ? 136.516 129.310 60.229  1.00 147.84 ? 1171 ILE A CD1 1 
ATOM   8263 N N   . ALA A 1 1213 ? 140.945 129.941 59.525  1.00 144.25 ? 1172 ALA A N   1 
ATOM   8264 C CA  . ALA A 1 1213 ? 142.047 129.924 60.482  1.00 144.25 ? 1172 ALA A CA  1 
ATOM   8265 C C   . ALA A 1 1213 ? 143.193 130.810 60.008  1.00 144.25 ? 1172 ALA A C   1 
ATOM   8266 O O   . ALA A 1 1213 ? 143.769 131.574 60.793  1.00 144.25 ? 1172 ALA A O   1 
ATOM   8267 C CB  . ALA A 1 1213 ? 142.530 128.492 60.703  1.00 144.25 ? 1172 ALA A CB  1 
ATOM   8268 N N   . ILE A 1 1214 ? 143.526 130.732 58.719  1.00 143.48 ? 1173 ILE A N   1 
ATOM   8269 C CA  . ILE A 1 1214 ? 144.551 131.604 58.155  1.00 143.48 ? 1173 ILE A CA  1 
ATOM   8270 C C   . ILE A 1 1214 ? 144.133 133.064 58.277  1.00 143.48 ? 1173 ILE A C   1 
ATOM   8271 O O   . ILE A 1 1214 ? 144.953 133.939 58.582  1.00 143.48 ? 1173 ILE A O   1 
ATOM   8272 C CB  . ILE A 1 1214 ? 144.837 131.212 56.694  1.00 143.48 ? 1173 ILE A CB  1 
ATOM   8273 C CG1 . ILE A 1 1214 ? 145.569 129.871 56.636  1.00 143.48 ? 1173 ILE A CG1 1 
ATOM   8274 C CG2 . ILE A 1 1214 ? 145.642 132.290 55.996  1.00 143.48 ? 1173 ILE A CG2 1 
ATOM   8275 C CD1 . ILE A 1 1214 ? 145.257 129.063 55.401  1.00 143.48 ? 1173 ILE A CD1 1 
ATOM   8276 N N   . ALA A 1 1215 ? 142.854 133.351 58.035  1.00 140.25 ? 1174 ALA A N   1 
ATOM   8277 C CA  . ALA A 1 1215 ? 142.372 134.722 58.157  1.00 140.25 ? 1174 ALA A CA  1 
ATOM   8278 C C   . ALA A 1 1215 ? 142.553 135.245 59.575  1.00 140.25 ? 1174 ALA A C   1 
ATOM   8279 O O   . ALA A 1 1215 ? 143.035 136.367 59.774  1.00 140.25 ? 1174 ALA A O   1 
ATOM   8280 C CB  . ALA A 1 1215 ? 140.904 134.800 57.737  1.00 140.25 ? 1174 ALA A CB  1 
ATOM   8281 N N   . ARG A 1 1216 ? 142.189 134.440 60.576  1.00 133.49 ? 1175 ARG A N   1 
ATOM   8282 C CA  . ARG A 1 1216 ? 142.371 134.874 61.958  1.00 133.49 ? 1175 ARG A CA  1 
ATOM   8283 C C   . ARG A 1 1216 ? 143.848 134.999 62.310  1.00 133.49 ? 1175 ARG A C   1 
ATOM   8284 O O   . ARG A 1 1216 ? 144.211 135.814 63.165  1.00 133.49 ? 1175 ARG A O   1 
ATOM   8285 C CB  . ARG A 1 1216 ? 141.662 133.921 62.925  1.00 133.49 ? 1175 ARG A CB  1 
ATOM   8286 C CG  . ARG A 1 1216 ? 142.531 132.821 63.511  1.00 133.49 ? 1175 ARG A CG  1 
ATOM   8287 C CD  . ARG A 1 1216 ? 141.678 131.684 64.049  1.00 133.49 ? 1175 ARG A CD  1 
ATOM   8288 N NE  . ARG A 1 1216 ? 142.482 130.596 64.592  1.00 133.49 ? 1175 ARG A NE  1 
ATOM   8289 C CZ  . ARG A 1 1216 ? 142.008 129.396 64.896  1.00 133.49 ? 1175 ARG A CZ  1 
ATOM   8290 N NH1 . ARG A 1 1216 ? 140.726 129.103 64.753  1.00 133.49 ? 1175 ARG A NH1 1 
ATOM   8291 N NH2 . ARG A 1 1216 ? 142.840 128.464 65.351  1.00 133.49 ? 1175 ARG A NH2 1 
ATOM   8292 N N   . ALA A 1 1217 ? 144.709 134.205 61.669  1.00 134.18 ? 1176 ALA A N   1 
ATOM   8293 C CA  . ALA A 1 1217 ? 146.145 134.399 61.842  1.00 134.18 ? 1176 ALA A CA  1 
ATOM   8294 C C   . ALA A 1 1217 ? 146.583 135.753 61.299  1.00 134.18 ? 1176 ALA A C   1 
ATOM   8295 O O   . ALA A 1 1217 ? 147.379 136.458 61.932  1.00 134.18 ? 1176 ALA A O   1 
ATOM   8296 C CB  . ALA A 1 1217 ? 146.913 133.270 61.158  1.00 134.18 ? 1176 ALA A CB  1 
ATOM   8297 N N   . LEU A 1 1218 ? 146.074 136.131 60.125  1.00 136.05 ? 1177 LEU A N   1 
ATOM   8298 C CA  . LEU A 1 1218 ? 146.400 137.440 59.560  1.00 136.05 ? 1177 LEU A CA  1 
ATOM   8299 C C   . LEU A 1 1218 ? 145.808 138.583 60.376  1.00 136.05 ? 1177 LEU A C   1 
ATOM   8300 O O   . LEU A 1 1218 ? 146.325 139.705 60.323  1.00 136.05 ? 1177 LEU A O   1 
ATOM   8301 C CB  . LEU A 1 1218 ? 145.938 137.542 58.105  1.00 136.05 ? 1177 LEU A CB  1 
ATOM   8302 C CG  . LEU A 1 1218 ? 146.825 136.987 56.985  1.00 136.05 ? 1177 LEU A CG  1 
ATOM   8303 C CD1 . LEU A 1 1218 ? 148.127 137.772 56.939  1.00 136.05 ? 1177 LEU A CD1 1 
ATOM   8304 C CD2 . LEU A 1 1218 ? 147.114 135.508 57.121  1.00 136.05 ? 1177 LEU A CD2 1 
ATOM   8305 N N   . VAL A 1 1219 ? 144.727 138.332 61.118  1.00 134.23 ? 1178 VAL A N   1 
ATOM   8306 C CA  . VAL A 1 1219 ? 144.158 139.381 61.962  1.00 134.23 ? 1178 VAL A CA  1 
ATOM   8307 C C   . VAL A 1 1219 ? 145.185 139.860 62.979  1.00 134.23 ? 1178 VAL A C   1 
ATOM   8308 O O   . VAL A 1 1219 ? 145.300 141.061 63.251  1.00 134.23 ? 1178 VAL A O   1 
ATOM   8309 C CB  . VAL A 1 1219 ? 142.876 138.886 62.654  1.00 134.23 ? 1178 VAL A CB  1 
ATOM   8310 C CG1 . VAL A 1 1219 ? 142.359 139.932 63.627  1.00 134.23 ? 1178 VAL A CG1 1 
ATOM   8311 C CG2 . VAL A 1 1219 ? 141.816 138.566 61.633  1.00 134.23 ? 1178 VAL A CG2 1 
ATOM   8312 N N   . ARG A 1 1220 ? 145.958 138.931 63.544  1.00 129.11 ? 1179 ARG A N   1 
ATOM   8313 C CA  . ARG A 1 1220 ? 146.932 139.280 64.570  1.00 129.11 ? 1179 ARG A CA  1 
ATOM   8314 C C   . ARG A 1 1220 ? 148.044 140.175 64.039  1.00 129.11 ? 1179 ARG A C   1 
ATOM   8315 O O   . ARG A 1 1220 ? 148.771 140.773 64.840  1.00 129.11 ? 1179 ARG A O   1 
ATOM   8316 C CB  . ARG A 1 1220 ? 147.529 138.006 65.170  1.00 129.11 ? 1179 ARG A CB  1 
ATOM   8317 C CG  . ARG A 1 1220 ? 148.137 138.186 66.549  1.00 129.11 ? 1179 ARG A CG  1 
ATOM   8318 C CD  . ARG A 1 1220 ? 148.503 136.845 67.158  1.00 129.11 ? 1179 ARG A CD  1 
ATOM   8319 N NE  . ARG A 1 1220 ? 148.753 136.935 68.592  1.00 129.11 ? 1179 ARG A NE  1 
ATOM   8320 C CZ  . ARG A 1 1220 ? 147.806 137.063 69.511  1.00 129.11 ? 1179 ARG A CZ  1 
ATOM   8321 N NH1 . ARG A 1 1220 ? 146.527 137.115 69.184  1.00 129.11 ? 1179 ARG A NH1 1 
ATOM   8322 N NH2 . ARG A 1 1220 ? 148.153 137.134 70.793  1.00 129.11 ? 1179 ARG A NH2 1 
ATOM   8323 N N   . LYS A 1 1221 ? 148.170 140.290 62.714  1.00 136.29 ? 1180 LYS A N   1 
ATOM   8324 C CA  . LYS A 1 1221 ? 149.246 141.025 62.037  1.00 136.29 ? 1180 LYS A CA  1 
ATOM   8325 C C   . LYS A 1 1221 ? 150.582 140.846 62.754  1.00 136.29 ? 1180 LYS A C   1 
ATOM   8326 O O   . LYS A 1 1221 ? 151.298 141.803 63.055  1.00 136.29 ? 1180 LYS A O   1 
ATOM   8327 C CB  . LYS A 1 1221 ? 148.904 142.512 61.864  1.00 136.29 ? 1180 LYS A CB  1 
ATOM   8328 C CG  . LYS A 1 1221 ? 148.301 143.225 63.065  1.00 136.29 ? 1180 LYS A CG  1 
ATOM   8329 C CD  . LYS A 1 1221 ? 148.412 144.734 62.927  1.00 136.29 ? 1180 LYS A CD  1 
ATOM   8330 C CE  . LYS A 1 1221 ? 147.623 145.447 64.014  1.00 136.29 ? 1180 LYS A CE  1 
ATOM   8331 N NZ  . LYS A 1 1221 ? 148.185 146.790 64.323  1.00 136.29 ? 1180 LYS A NZ  1 
ATOM   8332 N N   . ALA A 1 1222 ? 150.909 139.588 63.037  1.00 142.69 ? 1181 ALA A N   1 
ATOM   8333 C CA  . ALA A 1 1222 ? 152.168 139.255 63.686  1.00 142.69 ? 1181 ALA A CA  1 
ATOM   8334 C C   . ALA A 1 1222 ? 153.290 139.180 62.661  1.00 142.69 ? 1181 ALA A C   1 
ATOM   8335 O O   . ALA A 1 1222 ? 153.089 138.732 61.529  1.00 142.69 ? 1181 ALA A O   1 
ATOM   8336 C CB  . ALA A 1 1222 ? 152.049 137.927 64.432  1.00 142.69 ? 1181 ALA A CB  1 
ATOM   8337 N N   . GLU A 1 1223 ? 154.479 139.630 63.065  1.00 150.32 ? 1182 GLU A N   1 
ATOM   8338 C CA  . GLU A 1 1223 ? 155.628 139.580 62.166  1.00 150.32 ? 1182 GLU A CA  1 
ATOM   8339 C C   . GLU A 1 1223 ? 156.020 138.144 61.845  1.00 150.32 ? 1182 GLU A C   1 
ATOM   8340 O O   . GLU A 1 1223 ? 156.331 137.822 60.693  1.00 150.32 ? 1182 GLU A O   1 
ATOM   8341 C CB  . GLU A 1 1223 ? 156.805 140.338 62.775  1.00 150.32 ? 1182 GLU A CB  1 
ATOM   8342 C CG  . GLU A 1 1223 ? 156.533 141.816 62.994  1.00 150.32 ? 1182 GLU A CG  1 
ATOM   8343 C CD  . GLU A 1 1223 ? 155.927 142.102 64.353  1.00 150.32 ? 1182 GLU A CD  1 
ATOM   8344 O OE1 . GLU A 1 1223 ? 155.626 141.137 65.087  1.00 150.32 ? 1182 GLU A OE1 1 
ATOM   8345 O OE2 . GLU A 1 1223 ? 155.755 143.292 64.688  1.00 150.32 ? 1182 GLU A OE2 1 
ATOM   8346 N N   . ILE A 1 1224 ? 156.003 137.266 62.843  1.00 141.75 ? 1183 ILE A N   1 
ATOM   8347 C CA  . ILE A 1 1224 ? 156.396 135.872 62.677  1.00 141.75 ? 1183 ILE A CA  1 
ATOM   8348 C C   . ILE A 1 1224 ? 155.137 135.031 62.526  1.00 141.75 ? 1183 ILE A C   1 
ATOM   8349 O O   . ILE A 1 1224 ? 154.237 135.091 63.374  1.00 141.75 ? 1183 ILE A O   1 
ATOM   8350 C CB  . ILE A 1 1224 ? 157.247 135.384 63.860  1.00 141.75 ? 1183 ILE A CB  1 
ATOM   8351 C CG1 . ILE A 1 1224 ? 158.544 136.187 63.950  1.00 141.75 ? 1183 ILE A CG1 1 
ATOM   8352 C CG2 . ILE A 1 1224 ? 157.532 133.900 63.732  1.00 141.75 ? 1183 ILE A CG2 1 
ATOM   8353 C CD1 . ILE A 1 1224 ? 159.140 136.245 65.337  1.00 141.75 ? 1183 ILE A CD1 1 
ATOM   8354 N N   . MET A 1 1225 ? 155.072 134.255 61.444  1.00 142.64 ? 1184 MET A N   1 
ATOM   8355 C CA  . MET A 1 1225 ? 153.943 133.369 61.171  1.00 142.64 ? 1184 MET A CA  1 
ATOM   8356 C C   . MET A 1 1225 ? 154.451 131.933 61.128  1.00 142.64 ? 1184 MET A C   1 
ATOM   8357 O O   . MET A 1 1225 ? 155.361 131.617 60.357  1.00 142.64 ? 1184 MET A O   1 
ATOM   8358 C CB  . MET A 1 1225 ? 153.264 133.736 59.854  1.00 142.64 ? 1184 MET A CB  1 
ATOM   8359 C CG  . MET A 1 1225 ? 152.975 135.213 59.687  1.00 142.64 ? 1184 MET A CG  1 
ATOM   8360 S SD  . MET A 1 1225 ? 152.871 135.655 57.942  1.00 142.64 ? 1184 MET A SD  1 
ATOM   8361 C CE  . MET A 1 1225 ? 153.083 137.428 58.018  1.00 142.64 ? 1184 MET A CE  1 
ATOM   8362 N N   . LEU A 1 1226 ? 153.848 131.056 61.931  1.00 136.93 ? 1185 LEU A N   1 
ATOM   8363 C CA  . LEU A 1 1226 ? 154.279 129.663 62.037  1.00 136.93 ? 1185 LEU A CA  1 
ATOM   8364 C C   . LEU A 1 1226 ? 153.287 128.784 61.282  1.00 136.93 ? 1185 LEU A C   1 
ATOM   8365 O O   . LEU A 1 1226 ? 152.297 128.289 61.824  1.00 136.93 ? 1185 LEU A O   1 
ATOM   8366 C CB  . LEU A 1 1226 ? 154.397 129.255 63.499  1.00 136.93 ? 1185 LEU A CB  1 
ATOM   8367 C CG  . LEU A 1 1226 ? 155.381 130.076 64.330  1.00 136.93 ? 1185 LEU A CG  1 
ATOM   8368 C CD1 . LEU A 1 1226 ? 155.325 129.658 65.786  1.00 136.93 ? 1185 LEU A CD1 1 
ATOM   8369 C CD2 . LEU A 1 1226 ? 156.791 129.945 63.779  1.00 136.93 ? 1185 LEU A CD2 1 
ATOM   8370 N N   . LEU A 1 1227 ? 153.572 128.584 60.001  1.00 143.38 ? 1186 LEU A N   1 
ATOM   8371 C CA  . LEU A 1 1227 ? 152.666 127.830 59.146  1.00 143.38 ? 1186 LEU A CA  1 
ATOM   8372 C C   . LEU A 1 1227 ? 152.878 126.331 59.315  1.00 143.38 ? 1186 LEU A C   1 
ATOM   8373 O O   . LEU A 1 1227 ? 154.007 125.831 59.258  1.00 143.38 ? 1186 LEU A O   1 
ATOM   8374 C CB  . LEU A 1 1227 ? 152.861 128.226 57.681  1.00 143.38 ? 1186 LEU A CB  1 
ATOM   8375 C CG  . LEU A 1 1227 ? 152.149 129.469 57.138  1.00 143.38 ? 1186 LEU A CG  1 
ATOM   8376 C CD1 . LEU A 1 1227 ? 150.644 129.308 57.229  1.00 143.38 ? 1186 LEU A CD1 1 
ATOM   8377 C CD2 . LEU A 1 1227 ? 152.595 130.737 57.847  1.00 143.38 ? 1186 LEU A CD2 1 
ATOM   8378 N N   . ASP A 1 1228 ? 151.775 125.611 59.496  1.00 151.73 ? 1187 ASP A N   1 
ATOM   8379 C CA  . ASP A 1 1228 ? 151.790 124.173 59.706  1.00 151.73 ? 1187 ASP A CA  1 
ATOM   8380 C C   . ASP A 1 1228 ? 151.210 123.484 58.477  1.00 151.73 ? 1187 ASP A C   1 
ATOM   8381 O O   . ASP A 1 1228 ? 150.556 124.106 57.637  1.00 151.73 ? 1187 ASP A O   1 
ATOM   8382 C CB  . ASP A 1 1228 ? 151.002 123.794 60.969  1.00 151.73 ? 1187 ASP A CB  1 
ATOM   8383 C CG  . ASP A 1 1228 ? 151.158 122.333 61.351  1.00 151.73 ? 1187 ASP A CG  1 
ATOM   8384 O OD1 . ASP A 1 1228 ? 151.852 121.589 60.627  1.00 151.73 ? 1187 ASP A OD1 1 
ATOM   8385 O OD2 . ASP A 1 1228 ? 150.589 121.927 62.385  1.00 151.73 ? 1187 ASP A OD2 1 
ATOM   8386 N N   . GLU A 1 1229 ? 151.467 122.179 58.374  1.00 162.70 ? 1188 GLU A N   1 
ATOM   8387 C CA  . GLU A 1 1229 ? 150.971 121.365 57.264  1.00 162.70 ? 1188 GLU A CA  1 
ATOM   8388 C C   . GLU A 1 1229 ? 149.490 121.054 57.488  1.00 162.70 ? 1188 GLU A C   1 
ATOM   8389 O O   . GLU A 1 1229 ? 149.085 119.939 57.824  1.00 162.70 ? 1188 GLU A O   1 
ATOM   8390 C CB  . GLU A 1 1229 ? 151.806 120.099 57.120  1.00 162.70 ? 1188 GLU A CB  1 
ATOM   8391 C CG  . GLU A 1 1229 ? 151.447 119.218 55.927  1.00 162.70 ? 1188 GLU A CG  1 
ATOM   8392 C CD  . GLU A 1 1229 ? 151.696 119.887 54.587  1.00 162.70 ? 1188 GLU A CD  1 
ATOM   8393 O OE1 . GLU A 1 1229 ? 152.490 120.847 54.531  1.00 162.70 ? 1188 GLU A OE1 1 
ATOM   8394 O OE2 . GLU A 1 1229 ? 151.102 119.443 53.582  1.00 162.70 ? 1188 GLU A OE2 1 
ATOM   8395 N N   . ALA A 1 1230 ? 148.670 122.091 57.309  1.00 167.98 ? 1189 ALA A N   1 
ATOM   8396 C CA  . ALA A 1 1230 ? 147.226 121.915 57.412  1.00 167.98 ? 1189 ALA A CA  1 
ATOM   8397 C C   . ALA A 1 1230 ? 146.665 121.248 56.164  1.00 167.98 ? 1189 ALA A C   1 
ATOM   8398 O O   . ALA A 1 1230 ? 145.695 120.487 56.240  1.00 167.98 ? 1189 ALA A O   1 
ATOM   8399 C CB  . ALA A 1 1230 ? 146.548 123.262 57.657  1.00 167.98 ? 1189 ALA A CB  1 
ATOM   8400 N N   . THR A 1 1231 ? 147.265 121.524 55.005  1.00 174.65 ? 1190 THR A N   1 
ATOM   8401 C CA  . THR A 1 1231 ? 146.820 120.963 53.730  1.00 174.65 ? 1190 THR A CA  1 
ATOM   8402 C C   . THR A 1 1231 ? 147.254 119.502 53.663  1.00 174.65 ? 1190 THR A C   1 
ATOM   8403 O O   . THR A 1 1231 ? 148.302 119.149 53.118  1.00 174.65 ? 1190 THR A O   1 
ATOM   8404 C CB  . THR A 1 1231 ? 147.384 121.770 52.568  1.00 174.65 ? 1190 THR A CB  1 
ATOM   8405 O OG1 . THR A 1 1231 ? 147.200 123.170 52.819  1.00 174.65 ? 1190 THR A OG1 1 
ATOM   8406 C CG2 . THR A 1 1231 ? 146.695 121.395 51.271  1.00 174.65 ? 1190 THR A CG2 1 
ATOM   8407 N N   . SER A 1 1232 ? 146.421 118.633 54.236  1.00 178.22 ? 1191 SER A N   1 
ATOM   8408 C CA  . SER A 1 1232 ? 146.717 117.207 54.306  1.00 178.22 ? 1191 SER A CA  1 
ATOM   8409 C C   . SER A 1 1232 ? 145.749 116.372 53.477  1.00 178.22 ? 1191 SER A C   1 
ATOM   8410 O O   . SER A 1 1232 ? 146.181 115.617 52.601  1.00 178.22 ? 1191 SER A O   1 
ATOM   8411 C CB  . SER A 1 1232 ? 146.702 116.744 55.770  1.00 178.22 ? 1191 SER A CB  1 
ATOM   8412 O OG  . SER A 1 1232 ? 147.696 117.413 56.528  1.00 178.22 ? 1191 SER A OG  1 
ATOM   8413 N N   . ALA A 1 1233 ? 144.444 116.488 53.723  1.00 181.44 ? 1192 ALA A N   1 
ATOM   8414 C CA  . ALA A 1 1233 ? 143.431 115.687 53.035  1.00 181.44 ? 1192 ALA A CA  1 
ATOM   8415 C C   . ALA A 1 1233 ? 142.332 116.620 52.535  1.00 181.44 ? 1192 ALA A C   1 
ATOM   8416 O O   . ALA A 1 1233 ? 141.334 116.847 53.226  1.00 181.44 ? 1192 ALA A O   1 
ATOM   8417 C CB  . ALA A 1 1233 ? 142.875 114.604 53.955  1.00 181.44 ? 1192 ALA A CB  1 
ATOM   8418 N N   . LEU A 1 1234 ? 142.516 117.157 51.333  1.00 181.16 ? 1193 LEU A N   1 
ATOM   8419 C CA  . LEU A 1 1234 ? 141.542 118.047 50.719  1.00 181.16 ? 1193 LEU A CA  1 
ATOM   8420 C C   . LEU A 1 1234 ? 141.349 117.644 49.265  1.00 181.16 ? 1193 LEU A C   1 
ATOM   8421 O O   . LEU A 1 1234 ? 142.232 117.045 48.645  1.00 181.16 ? 1193 LEU A O   1 
ATOM   8422 C CB  . LEU A 1 1234 ? 141.981 119.518 50.803  1.00 181.16 ? 1193 LEU A CB  1 
ATOM   8423 C CG  . LEU A 1 1234 ? 141.703 120.331 52.072  1.00 181.16 ? 1193 LEU A CG  1 
ATOM   8424 C CD1 . LEU A 1 1234 ? 142.589 119.899 53.229  1.00 181.16 ? 1193 LEU A CD1 1 
ATOM   8425 C CD2 . LEU A 1 1234 ? 141.892 121.809 51.789  1.00 181.16 ? 1193 LEU A CD2 1 
ATOM   8426 N N   . ASP A 1 1235 ? 140.177 117.971 48.725  1.00 184.38 ? 1194 ASP A N   1 
ATOM   8427 C CA  . ASP A 1 1235 ? 139.930 117.751 47.309  1.00 184.38 ? 1194 ASP A CA  1 
ATOM   8428 C C   . ASP A 1 1235 ? 140.540 118.883 46.483  1.00 184.38 ? 1194 ASP A C   1 
ATOM   8429 O O   . ASP A 1 1235 ? 141.001 119.896 47.013  1.00 184.38 ? 1194 ASP A O   1 
ATOM   8430 C CB  . ASP A 1 1235 ? 138.432 117.613 47.033  1.00 184.38 ? 1194 ASP A CB  1 
ATOM   8431 C CG  . ASP A 1 1235 ? 137.623 118.748 47.615  1.00 184.38 ? 1194 ASP A CG  1 
ATOM   8432 O OD1 . ASP A 1 1235 ? 138.175 119.507 48.434  1.00 184.38 ? 1194 ASP A OD1 1 
ATOM   8433 O OD2 . ASP A 1 1235 ? 136.435 118.884 47.253  1.00 184.38 ? 1194 ASP A OD2 1 
ATOM   8434 N N   . ALA A 1 1236 ? 140.513 118.702 45.159  1.00 184.35 ? 1195 ALA A N   1 
ATOM   8435 C CA  . ALA A 1 1236 ? 141.333 119.520 44.267  1.00 184.35 ? 1195 ALA A CA  1 
ATOM   8436 C C   . ALA A 1 1236 ? 141.016 121.004 44.404  1.00 184.35 ? 1195 ALA A C   1 
ATOM   8437 O O   . ALA A 1 1236 ? 141.926 121.834 44.512  1.00 184.35 ? 1195 ALA A O   1 
ATOM   8438 C CB  . ALA A 1 1236 ? 141.141 119.062 42.821  1.00 184.35 ? 1195 ALA A CB  1 
ATOM   8439 N N   . GLU A 1 1237 ? 139.730 121.360 44.398  1.00 182.47 ? 1196 GLU A N   1 
ATOM   8440 C CA  . GLU A 1 1237 ? 139.360 122.770 44.492  1.00 182.47 ? 1196 GLU A CA  1 
ATOM   8441 C C   . GLU A 1 1237 ? 139.765 123.352 45.840  1.00 182.47 ? 1196 GLU A C   1 
ATOM   8442 O O   . GLU A 1 1237 ? 140.360 124.436 45.911  1.00 182.47 ? 1196 GLU A O   1 
ATOM   8443 C CB  . GLU A 1 1237 ? 137.859 122.937 44.261  1.00 182.47 ? 1196 GLU A CB  1 
ATOM   8444 C CG  . GLU A 1 1237 ? 137.370 124.362 44.445  1.00 182.47 ? 1196 GLU A CG  1 
ATOM   8445 C CD  . GLU A 1 1237 ? 138.225 125.368 43.701  1.00 182.47 ? 1196 GLU A CD  1 
ATOM   8446 O OE1 . GLU A 1 1237 ? 138.352 125.244 42.464  1.00 182.47 ? 1196 GLU A OE1 1 
ATOM   8447 O OE2 . GLU A 1 1237 ? 138.773 126.284 44.351  1.00 182.47 ? 1196 GLU A OE2 1 
ATOM   8448 N N   . SER A 1 1238 ? 139.454 122.640 46.926  1.00 182.04 ? 1197 SER A N   1 
ATOM   8449 C CA  . SER A 1 1238 ? 139.864 123.100 48.246  1.00 182.04 ? 1197 SER A CA  1 
ATOM   8450 C C   . SER A 1 1238 ? 141.380 123.109 48.375  1.00 182.04 ? 1197 SER A C   1 
ATOM   8451 O O   . SER A 1 1238 ? 141.944 123.995 49.022  1.00 182.04 ? 1197 SER A O   1 
ATOM   8452 C CB  . SER A 1 1238 ? 139.237 122.229 49.334  1.00 182.04 ? 1197 SER A CB  1 
ATOM   8453 O OG  . SER A 1 1238 ? 137.823 122.263 49.262  1.00 182.04 ? 1197 SER A OG  1 
ATOM   8454 N N   . GLU A 1 1239 ? 142.057 122.129 47.766  1.00 178.94 ? 1198 GLU A N   1 
ATOM   8455 C CA  . GLU A 1 1239 ? 143.516 122.129 47.768  1.00 178.94 ? 1198 GLU A CA  1 
ATOM   8456 C C   . GLU A 1 1239 ? 144.058 123.407 47.142  1.00 178.94 ? 1198 GLU A C   1 
ATOM   8457 O O   . GLU A 1 1239 ? 144.893 124.098 47.735  1.00 178.94 ? 1198 GLU A O   1 
ATOM   8458 C CB  . GLU A 1 1239 ? 144.046 120.908 47.015  1.00 178.94 ? 1198 GLU A CB  1 
ATOM   8459 C CG  . GLU A 1 1239 ? 143.998 119.599 47.784  1.00 178.94 ? 1198 GLU A CG  1 
ATOM   8460 C CD  . GLU A 1 1239 ? 145.207 119.389 48.669  1.00 178.94 ? 1198 GLU A CD  1 
ATOM   8461 O OE1 . GLU A 1 1239 ? 146.343 119.441 48.152  1.00 178.94 ? 1198 GLU A OE1 1 
ATOM   8462 O OE2 . GLU A 1 1239 ? 145.021 119.148 49.880  1.00 178.94 ? 1198 GLU A OE2 1 
ATOM   8463 N N   . ARG A 1 1240 ? 143.580 123.744 45.942  1.00 176.76 ? 1199 ARG A N   1 
ATOM   8464 C CA  . ARG A 1 1240 ? 144.079 124.933 45.260  1.00 176.76 ? 1199 ARG A CA  1 
ATOM   8465 C C   . ARG A 1 1240 ? 143.752 126.191 46.052  1.00 176.76 ? 1199 ARG A C   1 
ATOM   8466 O O   . ARG A 1 1240 ? 144.593 127.089 46.180  1.00 176.76 ? 1199 ARG A O   1 
ATOM   8467 C CB  . ARG A 1 1240 ? 143.501 125.007 43.847  1.00 176.76 ? 1199 ARG A CB  1 
ATOM   8468 C CG  . ARG A 1 1240 ? 144.096 126.103 42.965  1.00 176.76 ? 1199 ARG A CG  1 
ATOM   8469 C CD  . ARG A 1 1240 ? 143.335 127.418 43.073  1.00 176.76 ? 1199 ARG A CD  1 
ATOM   8470 N NE  . ARG A 1 1240 ? 141.948 127.284 42.645  1.00 176.76 ? 1199 ARG A NE  1 
ATOM   8471 C CZ  . ARG A 1 1240 ? 140.994 128.164 42.917  1.00 176.76 ? 1199 ARG A CZ  1 
ATOM   8472 N NH1 . ARG A 1 1240 ? 141.241 129.254 43.624  1.00 176.76 ? 1199 ARG A NH1 1 
ATOM   8473 N NH2 . ARG A 1 1240 ? 139.761 127.942 42.470  1.00 176.76 ? 1199 ARG A NH2 1 
ATOM   8474 N N   . SER A 1 1241 ? 142.536 126.270 46.599  1.00 176.01 ? 1200 SER A N   1 
ATOM   8475 C CA  . SER A 1 1241 ? 142.144 127.450 47.359  1.00 176.01 ? 1200 SER A CA  1 
ATOM   8476 C C   . SER A 1 1241 ? 143.010 127.623 48.602  1.00 176.01 ? 1200 SER A C   1 
ATOM   8477 O O   . SER A 1 1241 ? 143.459 128.734 48.912  1.00 176.01 ? 1200 SER A O   1 
ATOM   8478 C CB  . SER A 1 1241 ? 140.666 127.356 47.737  1.00 176.01 ? 1200 SER A CB  1 
ATOM   8479 O OG  . SER A 1 1241 ? 140.456 126.367 48.730  1.00 176.01 ? 1200 SER A OG  1 
ATOM   8480 N N   . VAL A 1 1242 ? 143.262 126.531 49.328  1.00 173.39 ? 1201 VAL A N   1 
ATOM   8481 C CA  . VAL A 1 1242 ? 144.030 126.643 50.562  1.00 173.39 ? 1201 VAL A CA  1 
ATOM   8482 C C   . VAL A 1 1242 ? 145.498 126.932 50.268  1.00 173.39 ? 1201 VAL A C   1 
ATOM   8483 O O   . VAL A 1 1242 ? 146.140 127.685 51.009  1.00 173.39 ? 1201 VAL A O   1 
ATOM   8484 C CB  . VAL A 1 1242 ? 143.845 125.387 51.437  1.00 173.39 ? 1201 VAL A CB  1 
ATOM   8485 C CG1 . VAL A 1 1242 ? 144.550 124.187 50.843  1.00 173.39 ? 1201 VAL A CG1 1 
ATOM   8486 C CG2 . VAL A 1 1242 ? 144.335 125.653 52.852  1.00 173.39 ? 1201 VAL A CG2 1 
ATOM   8487 N N   . GLN A 1 1243 ? 146.060 126.371 49.190  1.00 170.99 ? 1202 GLN A N   1 
ATOM   8488 C CA  . GLN A 1 1243 ? 147.431 126.741 48.847  1.00 170.99 ? 1202 GLN A CA  1 
ATOM   8489 C C   . GLN A 1 1243 ? 147.521 128.188 48.383  1.00 170.99 ? 1202 GLN A C   1 
ATOM   8490 O O   . GLN A 1 1243 ? 148.507 128.867 48.683  1.00 170.99 ? 1202 GLN A O   1 
ATOM   8491 C CB  . GLN A 1 1243 ? 148.017 125.799 47.795  1.00 170.99 ? 1202 GLN A CB  1 
ATOM   8492 C CG  . GLN A 1 1243 ? 147.809 124.326 48.082  1.00 170.99 ? 1202 GLN A CG  1 
ATOM   8493 C CD  . GLN A 1 1243 ? 148.836 123.446 47.398  1.00 170.99 ? 1202 GLN A CD  1 
ATOM   8494 O OE1 . GLN A 1 1243 ? 149.074 123.570 46.197  1.00 170.99 ? 1202 GLN A OE1 1 
ATOM   8495 N NE2 . GLN A 1 1243 ? 149.454 122.554 48.163  1.00 170.99 ? 1202 GLN A NE2 1 
ATOM   8496 N N   . GLU A 1 1244 ? 146.502 128.691 47.682  1.00 167.70 ? 1203 GLU A N   1 
ATOM   8497 C CA  . GLU A 1 1244 ? 146.477 130.113 47.360  1.00 167.70 ? 1203 GLU A CA  1 
ATOM   8498 C C   . GLU A 1 1244 ? 146.466 130.958 48.629  1.00 167.70 ? 1203 GLU A C   1 
ATOM   8499 O O   . GLU A 1 1244 ? 147.263 131.898 48.769  1.00 167.70 ? 1203 GLU A O   1 
ATOM   8500 C CB  . GLU A 1 1244 ? 145.259 130.431 46.494  1.00 167.70 ? 1203 GLU A CB  1 
ATOM   8501 C CG  . GLU A 1 1244 ? 145.099 131.903 46.154  1.00 167.70 ? 1203 GLU A CG  1 
ATOM   8502 C CD  . GLU A 1 1244 ? 146.014 132.349 45.032  1.00 167.70 ? 1203 GLU A CD  1 
ATOM   8503 O OE1 . GLU A 1 1244 ? 146.698 131.488 44.439  1.00 167.70 ? 1203 GLU A OE1 1 
ATOM   8504 O OE2 . GLU A 1 1244 ? 146.050 133.563 44.740  1.00 167.70 ? 1203 GLU A OE2 1 
ATOM   8505 N N   . ALA A 1 1245 ? 145.588 130.614 49.575  1.00 165.32 ? 1204 ALA A N   1 
ATOM   8506 C CA  . ALA A 1 1245 ? 145.508 131.360 50.826  1.00 165.32 ? 1204 ALA A CA  1 
ATOM   8507 C C   . ALA A 1 1245 ? 146.834 131.320 51.572  1.00 165.32 ? 1204 ALA A C   1 
ATOM   8508 O O   . ALA A 1 1245 ? 147.264 132.329 52.141  1.00 165.32 ? 1204 ALA A O   1 
ATOM   8509 C CB  . ALA A 1 1245 ? 144.381 130.807 51.696  1.00 165.32 ? 1204 ALA A CB  1 
ATOM   8510 N N   . LEU A 1 1246 ? 147.498 130.163 51.573  1.00 163.79 ? 1205 LEU A N   1 
ATOM   8511 C CA  . LEU A 1 1246 ? 148.843 130.077 52.132  1.00 163.79 ? 1205 LEU A CA  1 
ATOM   8512 C C   . LEU A 1 1246 ? 149.800 131.005 51.398  1.00 163.79 ? 1205 LEU A C   1 
ATOM   8513 O O   . LEU A 1 1246 ? 150.694 131.599 52.010  1.00 163.79 ? 1205 LEU A O   1 
ATOM   8514 C CB  . LEU A 1 1246 ? 149.348 128.635 52.065  1.00 163.79 ? 1205 LEU A CB  1 
ATOM   8515 C CG  . LEU A 1 1246 ? 148.695 127.612 52.994  1.00 163.79 ? 1205 LEU A CG  1 
ATOM   8516 C CD1 . LEU A 1 1246 ? 149.465 126.302 52.973  1.00 163.79 ? 1205 LEU A CD1 1 
ATOM   8517 C CD2 . LEU A 1 1246 ? 148.616 128.161 54.404  1.00 163.79 ? 1205 LEU A CD2 1 
ATOM   8518 N N   . ASP A 1 1247 ? 149.635 131.128 50.078  1.00 164.39 ? 1206 ASP A N   1 
ATOM   8519 C CA  . ASP A 1 1247 ? 150.504 132.006 49.302  1.00 164.39 ? 1206 ASP A CA  1 
ATOM   8520 C C   . ASP A 1 1247 ? 150.380 133.451 49.765  1.00 164.39 ? 1206 ASP A C   1 
ATOM   8521 O O   . ASP A 1 1247 ? 151.391 134.138 49.962  1.00 164.39 ? 1206 ASP A O   1 
ATOM   8522 C CB  . ASP A 1 1247 ? 150.182 131.887 47.812  1.00 164.39 ? 1206 ASP A CB  1 
ATOM   8523 C CG  . ASP A 1 1247 ? 150.504 130.518 47.254  1.00 164.39 ? 1206 ASP A CG  1 
ATOM   8524 O OD1 . ASP A 1 1247 ? 151.094 129.698 47.988  1.00 164.39 ? 1206 ASP A OD1 1 
ATOM   8525 O OD2 . ASP A 1 1247 ? 150.161 130.258 46.080  1.00 164.39 ? 1206 ASP A OD2 1 
ATOM   8526 N N   . GLN A 1 1248 ? 149.149 133.940 49.948  1.00 162.59 ? 1207 GLN A N   1 
ATOM   8527 C CA  . GLN A 1 1248 ? 149.036 135.307 50.467  1.00 162.59 ? 1207 GLN A CA  1 
ATOM   8528 C C   . GLN A 1 1248 ? 149.468 135.390 51.929  1.00 162.59 ? 1207 GLN A C   1 
ATOM   8529 O O   . GLN A 1 1248 ? 150.005 136.417 52.359  1.00 162.59 ? 1207 GLN A O   1 
ATOM   8530 C CB  . GLN A 1 1248 ? 147.636 135.923 50.315  1.00 162.59 ? 1207 GLN A CB  1 
ATOM   8531 C CG  . GLN A 1 1248 ? 147.152 136.208 48.891  1.00 162.59 ? 1207 GLN A CG  1 
ATOM   8532 C CD  . GLN A 1 1248 ? 146.560 135.015 48.202  1.00 162.59 ? 1207 GLN A CD  1 
ATOM   8533 O OE1 . GLN A 1 1248 ? 146.192 134.050 48.851  1.00 162.59 ? 1207 GLN A OE1 1 
ATOM   8534 N NE2 . GLN A 1 1248 ? 146.464 135.071 46.879  1.00 162.59 ? 1207 GLN A NE2 1 
ATOM   8535 N N   . ALA A 1 1249 ? 149.239 134.332 52.710  1.00 160.17 ? 1208 ALA A N   1 
ATOM   8536 C CA  . ALA A 1 1249 ? 149.553 134.385 54.135  1.00 160.17 ? 1208 ALA A CA  1 
ATOM   8537 C C   . ALA A 1 1249 ? 151.053 134.492 54.374  1.00 160.17 ? 1208 ALA A C   1 
ATOM   8538 O O   . ALA A 1 1249 ? 151.514 135.371 55.112  1.00 160.17 ? 1208 ALA A O   1 
ATOM   8539 C CB  . ALA A 1 1249 ? 148.986 133.155 54.842  1.00 160.17 ? 1208 ALA A CB  1 
ATOM   8540 N N   . CYS A 1 1250 ? 151.835 133.608 53.752  1.00 160.15 ? 1209 CYS A N   1 
ATOM   8541 C CA  . CYS A 1 1250 ? 153.277 133.619 53.968  1.00 160.15 ? 1209 CYS A CA  1 
ATOM   8542 C C   . CYS A 1 1250 ? 153.931 134.842 53.341  1.00 160.15 ? 1209 CYS A C   1 
ATOM   8543 O O   . CYS A 1 1250 ? 155.048 135.209 53.725  1.00 160.15 ? 1209 CYS A O   1 
ATOM   8544 C CB  . CYS A 1 1250 ? 153.901 132.338 53.416  1.00 160.15 ? 1209 CYS A CB  1 
ATOM   8545 S SG  . CYS A 1 1250 ? 153.853 132.198 51.616  1.00 160.15 ? 1209 CYS A SG  1 
ATOM   8546 N N   . SER A 1 1251 ? 153.262 135.476 52.382  1.00 159.06 ? 1210 SER A N   1 
ATOM   8547 C CA  . SER A 1 1251 ? 153.816 136.661 51.745  1.00 159.06 ? 1210 SER A CA  1 
ATOM   8548 C C   . SER A 1 1251 ? 153.928 137.804 52.745  1.00 159.06 ? 1210 SER A C   1 
ATOM   8549 O O   . SER A 1 1251 ? 152.992 138.086 53.499  1.00 159.06 ? 1210 SER A O   1 
ATOM   8550 C CB  . SER A 1 1251 ? 152.944 137.080 50.562  1.00 159.06 ? 1210 SER A CB  1 
ATOM   8551 O OG  . SER A 1 1251 ? 151.640 137.425 50.994  1.00 159.06 ? 1210 SER A OG  1 
ATOM   8552 N N   . GLY A 1 1252 ? 155.084 138.462 52.750  1.00 155.63 ? 1211 GLY A N   1 
ATOM   8553 C CA  . GLY A 1 1252 ? 155.313 139.575 53.649  1.00 155.63 ? 1211 GLY A CA  1 
ATOM   8554 C C   . GLY A 1 1252 ? 155.737 139.141 55.035  1.00 155.63 ? 1211 GLY A C   1 
ATOM   8555 O O   . GLY A 1 1252 ? 155.330 138.077 55.511  1.00 155.63 ? 1211 GLY A O   1 
ATOM   8556 N N   . ARG A 1 1253 ? 156.553 139.961 55.688  1.00 150.98 ? 1212 ARG A N   1 
ATOM   8557 C CA  . ARG A 1 1253 ? 157.070 139.689 57.037  1.00 150.98 ? 1212 ARG A CA  1 
ATOM   8558 C C   . ARG A 1 1253 ? 157.829 138.358 56.998  1.00 150.98 ? 1212 ARG A C   1 
ATOM   8559 O O   . ARG A 1 1253 ? 158.336 137.951 55.945  1.00 150.98 ? 1212 ARG A O   1 
ATOM   8560 C CB  . ARG A 1 1253 ? 155.936 139.765 58.044  1.00 150.98 ? 1212 ARG A CB  1 
ATOM   8561 C CG  . ARG A 1 1253 ? 155.201 141.100 58.007  1.00 150.98 ? 1212 ARG A CG  1 
ATOM   8562 C CD  . ARG A 1 1253 ? 154.349 141.339 59.247  1.00 150.98 ? 1212 ARG A CD  1 
ATOM   8563 N NE  . ARG A 1 1253 ? 153.161 140.494 59.295  1.00 150.98 ? 1212 ARG A NE  1 
ATOM   8564 C CZ  . ARG A 1 1253 ? 152.059 140.712 58.590  1.00 150.98 ? 1212 ARG A CZ  1 
ATOM   8565 N NH1 . ARG A 1 1253 ? 151.962 141.736 57.757  1.00 150.98 ? 1212 ARG A NH1 1 
ATOM   8566 N NH2 . ARG A 1 1253 ? 151.026 139.886 58.729  1.00 150.98 ? 1212 ARG A NH2 1 
ATOM   8567 N N   . THR A 1 1254 ? 157.930 137.664 58.129  1.00 150.87 ? 1213 THR A N   1 
ATOM   8568 C CA  . THR A 1 1254 ? 158.693 136.427 58.202  1.00 150.87 ? 1213 THR A CA  1 
ATOM   8569 C C   . THR A 1 1254 ? 157.801 135.267 58.622  1.00 150.87 ? 1213 THR A C   1 
ATOM   8570 O O   . THR A 1 1254 ? 156.905 135.410 59.461  1.00 150.87 ? 1213 THR A O   1 
ATOM   8571 C CB  . THR A 1 1254 ? 159.883 136.552 59.166  1.00 150.87 ? 1213 THR A CB  1 
ATOM   8572 O OG1 . THR A 1 1254 ? 160.592 135.308 59.215  1.00 150.87 ? 1213 THR A OG1 1 
ATOM   8573 C CG2 . THR A 1 1254 ? 159.422 136.928 60.559  1.00 150.87 ? 1213 THR A CG2 1 
ATOM   8574 N N   . SER A 1 1255 ? 158.053 134.109 58.020  1.00 149.17 ? 1214 SER A N   1 
ATOM   8575 C CA  . SER A 1 1255 ? 157.230 132.937 58.275  1.00 149.17 ? 1214 SER A CA  1 
ATOM   8576 C C   . SER A 1 1255 ? 158.102 131.694 58.292  1.00 149.17 ? 1214 SER A C   1 
ATOM   8577 O O   . SER A 1 1255 ? 158.902 131.479 57.378  1.00 149.17 ? 1214 SER A O   1 
ATOM   8578 C CB  . SER A 1 1255 ? 156.129 132.799 57.219  1.00 149.17 ? 1214 SER A CB  1 
ATOM   8579 O OG  . SER A 1 1255 ? 156.680 132.526 55.944  1.00 149.17 ? 1214 SER A OG  1 
ATOM   8580 N N   . ILE A 1 1256 ? 157.936 130.887 59.331  1.00 143.77 ? 1215 ILE A N   1 
ATOM   8581 C CA  . ILE A 1 1256 ? 158.527 129.558 59.411  1.00 143.77 ? 1215 ILE A CA  1 
ATOM   8582 C C   . ILE A 1 1256 ? 157.436 128.560 59.064  1.00 143.77 ? 1215 ILE A C   1 
ATOM   8583 O O   . ILE A 1 1256 ? 156.453 128.420 59.801  1.00 143.77 ? 1215 ILE A O   1 
ATOM   8584 C CB  . ILE A 1 1256 ? 159.109 129.280 60.805  1.00 143.77 ? 1215 ILE A CB  1 
ATOM   8585 C CG1 . ILE A 1 1256 ? 159.864 130.502 61.330  1.00 143.77 ? 1215 ILE A CG1 1 
ATOM   8586 C CG2 . ILE A 1 1256 ? 160.018 128.064 60.765  1.00 143.77 ? 1215 ILE A CG2 1 
ATOM   8587 C CD1 . ILE A 1 1256 ? 160.965 130.987 60.414  1.00 143.77 ? 1215 ILE A CD1 1 
ATOM   8588 N N   . VAL A 1 1257 ? 157.590 127.882 57.934  1.00 147.25 ? 1216 VAL A N   1 
ATOM   8589 C CA  . VAL A 1 1257 ? 156.595 126.947 57.434  1.00 147.25 ? 1216 VAL A CA  1 
ATOM   8590 C C   . VAL A 1 1257 ? 157.151 125.541 57.575  1.00 147.25 ? 1216 VAL A C   1 
ATOM   8591 O O   . VAL A 1 1257 ? 158.359 125.330 57.439  1.00 147.25 ? 1216 VAL A O   1 
ATOM   8592 C CB  . VAL A 1 1257 ? 156.229 127.246 55.965  1.00 147.25 ? 1216 VAL A CB  1 
ATOM   8593 C CG1 . VAL A 1 1257 ? 155.039 126.408 55.521  1.00 147.25 ? 1216 VAL A CG1 1 
ATOM   8594 C CG2 . VAL A 1 1257 ? 155.949 128.728 55.783  1.00 147.25 ? 1216 VAL A CG2 1 
ATOM   8595 N N   . VAL A 1 1258 ? 156.279 124.585 57.874  1.00 151.93 ? 1217 VAL A N   1 
ATOM   8596 C CA  . VAL A 1 1258 ? 156.620 123.169 57.819  1.00 151.93 ? 1217 VAL A CA  1 
ATOM   8597 C C   . VAL A 1 1258 ? 155.734 122.517 56.768  1.00 151.93 ? 1217 VAL A C   1 
ATOM   8598 O O   . VAL A 1 1258 ? 154.518 122.740 56.748  1.00 151.93 ? 1217 VAL A O   1 
ATOM   8599 C CB  . VAL A 1 1258 ? 156.479 122.489 59.193  1.00 151.93 ? 1217 VAL A CB  1 
ATOM   8600 C CG1 . VAL A 1 1258 ? 157.439 123.121 60.187  1.00 151.93 ? 1217 VAL A CG1 1 
ATOM   8601 C CG2 . VAL A 1 1258 ? 155.058 122.594 59.713  1.00 151.93 ? 1217 VAL A CG2 1 
ATOM   8602 N N   . ALA A 1 1259 ? 156.342 121.742 55.869  1.00 164.43 ? 1218 ALA A N   1 
ATOM   8603 C CA  . ALA A 1 1259 ? 155.586 121.195 54.754  1.00 164.43 ? 1218 ALA A CA  1 
ATOM   8604 C C   . ALA A 1 1259 ? 156.171 119.856 54.331  1.00 164.43 ? 1218 ALA A C   1 
ATOM   8605 O O   . ALA A 1 1259 ? 157.323 119.531 54.629  1.00 164.43 ? 1218 ALA A O   1 
ATOM   8606 C CB  . ALA A 1 1259 ? 155.565 122.161 53.564  1.00 164.43 ? 1218 ALA A CB  1 
ATOM   8607 N N   . HIS A 1 1260 ? 155.342 119.077 53.630  1.00 174.13 ? 1219 HIS A N   1 
ATOM   8608 C CA  . HIS A 1 1260 ? 155.781 117.815 53.051  1.00 174.13 ? 1219 HIS A CA  1 
ATOM   8609 C C   . HIS A 1 1260 ? 155.272 117.632 51.625  1.00 174.13 ? 1219 HIS A C   1 
ATOM   8610 O O   . HIS A 1 1260 ? 155.444 116.545 51.058  1.00 174.13 ? 1219 HIS A O   1 
ATOM   8611 C CB  . HIS A 1 1260 ? 155.335 116.633 53.929  1.00 174.13 ? 1219 HIS A CB  1 
ATOM   8612 C CG  . HIS A 1 1260 ? 153.919 116.200 53.697  1.00 174.13 ? 1219 HIS A CG  1 
ATOM   8613 N ND1 . HIS A 1 1260 ? 152.863 116.682 54.440  1.00 174.13 ? 1219 HIS A ND1 1 
ATOM   8614 C CD2 . HIS A 1 1260 ? 153.387 115.313 52.822  1.00 174.13 ? 1219 HIS A CD2 1 
ATOM   8615 C CE1 . HIS A 1 1260 ? 151.742 116.123 54.024  1.00 174.13 ? 1219 HIS A CE1 1 
ATOM   8616 N NE2 . HIS A 1 1260 ? 152.032 115.288 53.042  1.00 174.13 ? 1219 HIS A NE2 1 
ATOM   8617 N N   . ARG A 1 1261 ? 154.676 118.659 51.024  1.00 181.40 ? 1220 ARG A N   1 
ATOM   8618 C CA  . ARG A 1 1261 ? 154.093 118.568 49.694  1.00 181.40 ? 1220 ARG A CA  1 
ATOM   8619 C C   . ARG A 1 1261 ? 154.790 119.549 48.763  1.00 181.40 ? 1220 ARG A C   1 
ATOM   8620 O O   . ARG A 1 1261 ? 155.154 120.654 49.172  1.00 181.40 ? 1220 ARG A O   1 
ATOM   8621 C CB  . ARG A 1 1261 ? 152.585 118.854 49.738  1.00 181.40 ? 1220 ARG A CB  1 
ATOM   8622 C CG  . ARG A 1 1261 ? 151.906 118.903 48.380  1.00 181.40 ? 1220 ARG A CG  1 
ATOM   8623 C CD  . ARG A 1 1261 ? 150.423 118.599 48.498  1.00 181.40 ? 1220 ARG A CD  1 
ATOM   8624 N NE  . ARG A 1 1261 ? 150.162 117.540 49.466  1.00 181.40 ? 1220 ARG A NE  1 
ATOM   8625 C CZ  . ARG A 1 1261 ? 149.390 117.676 50.536  1.00 181.40 ? 1220 ARG A CZ  1 
ATOM   8626 N NH1 . ARG A 1 1261 ? 148.787 118.820 50.812  1.00 181.40 ? 1220 ARG A NH1 1 
ATOM   8627 N NH2 . ARG A 1 1261 ? 149.219 116.637 51.349  1.00 181.40 ? 1220 ARG A NH2 1 
ATOM   8628 N N   . LEU A 1 1262 ? 154.977 119.133 47.511  1.00 187.95 ? 1221 LEU A N   1 
ATOM   8629 C CA  . LEU A 1 1262 ? 155.617 119.981 46.520  1.00 187.95 ? 1221 LEU A CA  1 
ATOM   8630 C C   . LEU A 1 1262 ? 154.754 121.209 46.230  1.00 187.95 ? 1221 LEU A C   1 
ATOM   8631 O O   . LEU A 1 1262 ? 153.593 121.303 46.640  1.00 187.95 ? 1221 LEU A O   1 
ATOM   8632 C CB  . LEU A 1 1262 ? 155.882 119.193 45.237  1.00 187.95 ? 1221 LEU A CB  1 
ATOM   8633 C CG  . LEU A 1 1262 ? 157.028 119.671 44.342  1.00 187.95 ? 1221 LEU A CG  1 
ATOM   8634 C CD1 . LEU A 1 1262 ? 158.342 119.692 45.108  1.00 187.95 ? 1221 LEU A CD1 1 
ATOM   8635 C CD2 . LEU A 1 1262 ? 157.141 118.803 43.098  1.00 187.95 ? 1221 LEU A CD2 1 
ATOM   8636 N N   . SER A 1 1263 ? 155.350 122.165 45.517  1.00 185.89 ? 1222 SER A N   1 
ATOM   8637 C CA  . SER A 1 1263 ? 154.726 123.441 45.173  1.00 185.89 ? 1222 SER A CA  1 
ATOM   8638 C C   . SER A 1 1263 ? 154.391 124.268 46.409  1.00 185.89 ? 1222 SER A C   1 
ATOM   8639 O O   . SER A 1 1263 ? 153.601 125.215 46.333  1.00 185.89 ? 1222 SER A O   1 
ATOM   8640 C CB  . SER A 1 1263 ? 153.473 123.241 44.311  1.00 185.89 ? 1222 SER A CB  1 
ATOM   8641 O OG  . SER A 1 1263 ? 153.760 122.450 43.172  1.00 185.89 ? 1222 SER A OG  1 
ATOM   8642 N N   . THR A 1 1264 ? 154.982 123.925 47.551  1.00 182.98 ? 1223 THR A N   1 
ATOM   8643 C CA  . THR A 1 1264 ? 154.798 124.666 48.791  1.00 182.98 ? 1223 THR A CA  1 
ATOM   8644 C C   . THR A 1 1264 ? 156.092 125.293 49.280  1.00 182.98 ? 1223 THR A C   1 
ATOM   8645 O O   . THR A 1 1264 ? 156.128 126.500 49.548  1.00 182.98 ? 1223 THR A O   1 
ATOM   8646 C CB  . THR A 1 1264 ? 154.215 123.748 49.877  1.00 182.98 ? 1223 THR A CB  1 
ATOM   8647 O OG1 . THR A 1 1264 ? 155.154 122.708 50.180  1.00 182.98 ? 1223 THR A OG1 1 
ATOM   8648 C CG2 . THR A 1 1264 ? 152.911 123.124 49.402  1.00 182.98 ? 1223 THR A CG2 1 
ATOM   8649 N N   . ILE A 1 1265 ? 157.164 124.505 49.402  1.00 182.78 ? 1224 ILE A N   1 
ATOM   8650 C CA  . ILE A 1 1265 ? 158.465 125.061 49.767  1.00 182.78 ? 1224 ILE A CA  1 
ATOM   8651 C C   . ILE A 1 1265 ? 159.160 125.726 48.594  1.00 182.78 ? 1224 ILE A C   1 
ATOM   8652 O O   . ILE A 1 1265 ? 160.133 126.462 48.800  1.00 182.78 ? 1224 ILE A O   1 
ATOM   8653 C CB  . ILE A 1 1265 ? 159.396 123.981 50.348  1.00 182.78 ? 1224 ILE A CB  1 
ATOM   8654 C CG1 . ILE A 1 1265 ? 159.784 122.972 49.265  1.00 182.78 ? 1224 ILE A CG1 1 
ATOM   8655 C CG2 . ILE A 1 1265 ? 158.731 123.281 51.523  1.00 182.78 ? 1224 ILE A CG2 1 
ATOM   8656 C CD1 . ILE A 1 1265 ? 160.907 122.045 49.672  1.00 182.78 ? 1224 ILE A CD1 1 
ATOM   8657 N N   . ARG A 1 1266 ? 158.691 125.485 47.367  1.00 183.56 ? 1225 ARG A N   1 
ATOM   8658 C CA  . ARG A 1 1266 ? 159.299 126.119 46.203  1.00 183.56 ? 1225 ARG A CA  1 
ATOM   8659 C C   . ARG A 1 1266 ? 159.178 127.634 46.278  1.00 183.56 ? 1225 ARG A C   1 
ATOM   8660 O O   . ARG A 1 1266 ? 160.106 128.358 45.898  1.00 183.56 ? 1225 ARG A O   1 
ATOM   8661 C CB  . ARG A 1 1266 ? 158.652 125.590 44.922  1.00 183.56 ? 1225 ARG A CB  1 
ATOM   8662 C CG  . ARG A 1 1266 ? 159.071 124.175 44.557  1.00 183.56 ? 1225 ARG A CG  1 
ATOM   8663 C CD  . ARG A 1 1266 ? 160.554 124.110 44.227  1.00 183.56 ? 1225 ARG A CD  1 
ATOM   8664 N NE  . ARG A 1 1266 ? 160.996 125.284 43.484  1.00 183.56 ? 1225 ARG A NE  1 
ATOM   8665 C CZ  . ARG A 1 1266 ? 162.032 125.301 42.658  1.00 183.56 ? 1225 ARG A CZ  1 
ATOM   8666 N NH1 . ARG A 1 1266 ? 162.764 124.220 42.442  1.00 183.56 ? 1225 ARG A NH1 1 
ATOM   8667 N NH2 . ARG A 1 1266 ? 162.343 126.433 42.032  1.00 183.56 ? 1225 ARG A NH2 1 
ATOM   8668 N N   . ASN A 1 1267 ? 158.038 128.130 46.763  1.00 182.83 ? 1226 ASN A N   1 
ATOM   8669 C CA  . ASN A 1 1267 ? 157.865 129.569 46.923  1.00 182.83 ? 1226 ASN A CA  1 
ATOM   8670 C C   . ASN A 1 1267 ? 158.857 130.133 47.931  1.00 182.83 ? 1226 ASN A C   1 
ATOM   8671 O O   . ASN A 1 1267 ? 159.398 131.228 47.736  1.00 182.83 ? 1226 ASN A O   1 
ATOM   8672 C CB  . ASN A 1 1267 ? 156.429 129.877 47.348  1.00 182.83 ? 1226 ASN A CB  1 
ATOM   8673 C CG  . ASN A 1 1267 ? 155.407 129.062 46.579  1.00 182.83 ? 1226 ASN A CG  1 
ATOM   8674 O OD1 . ASN A 1 1267 ? 154.470 128.512 47.160  1.00 182.83 ? 1226 ASN A OD1 1 
ATOM   8675 N ND2 . ASN A 1 1267 ? 155.582 128.981 45.265  1.00 182.83 ? 1226 ASN A ND2 1 
ATOM   8676 N N   . ALA A 1 1268 ? 159.105 129.404 49.016  1.00 176.81 ? 1227 ALA A N   1 
ATOM   8677 C CA  . ALA A 1 1268 ? 160.067 129.849 50.014  1.00 176.81 ? 1227 ALA A CA  1 
ATOM   8678 C C   . ALA A 1 1268 ? 161.476 129.838 49.437  1.00 176.81 ? 1227 ALA A C   1 
ATOM   8679 O O   . ALA A 1 1268 ? 161.847 128.941 48.675  1.00 176.81 ? 1227 ALA A O   1 
ATOM   8680 C CB  . ALA A 1 1268 ? 159.998 128.960 51.253  1.00 176.81 ? 1227 ALA A CB  1 
ATOM   8681 N N   . HIS A 1 1269 ? 162.263 130.848 49.804  1.00 170.53 ? 1228 HIS A N   1 
ATOM   8682 C CA  . HIS A 1 1269 ? 163.618 130.999 49.292  1.00 170.53 ? 1228 HIS A CA  1 
ATOM   8683 C C   . HIS A 1 1269 ? 164.686 130.423 50.212  1.00 170.53 ? 1228 HIS A C   1 
ATOM   8684 O O   . HIS A 1 1269 ? 165.856 130.379 49.817  1.00 170.53 ? 1228 HIS A O   1 
ATOM   8685 C CB  . HIS A 1 1269 ? 163.920 132.479 49.026  1.00 170.53 ? 1228 HIS A CB  1 
ATOM   8686 C CG  . HIS A 1 1269 ? 163.465 133.394 50.118  1.00 170.53 ? 1228 HIS A CG  1 
ATOM   8687 N ND1 . HIS A 1 1269 ? 162.157 133.811 50.241  1.00 170.53 ? 1228 HIS A ND1 1 
ATOM   8688 C CD2 . HIS A 1 1269 ? 164.140 133.963 51.143  1.00 170.53 ? 1228 HIS A CD2 1 
ATOM   8689 C CE1 . HIS A 1 1269 ? 162.048 134.607 51.289  1.00 170.53 ? 1228 HIS A CE1 1 
ATOM   8690 N NE2 . HIS A 1 1269 ? 163.236 134.713 51.855  1.00 170.53 ? 1228 HIS A NE2 1 
ATOM   8691 N N   . VAL A 1 1270 ? 164.327 129.993 51.419  1.00 169.97 ? 1229 VAL A N   1 
ATOM   8692 C CA  . VAL A 1 1270 ? 165.262 129.350 52.334  1.00 169.97 ? 1229 VAL A CA  1 
ATOM   8693 C C   . VAL A 1 1270 ? 164.641 128.044 52.806  1.00 169.97 ? 1229 VAL A C   1 
ATOM   8694 O O   . VAL A 1 1270 ? 163.520 128.038 53.326  1.00 169.97 ? 1229 VAL A O   1 
ATOM   8695 C CB  . VAL A 1 1270 ? 165.608 130.250 53.536  1.00 169.97 ? 1229 VAL A CB  1 
ATOM   8696 C CG1 . VAL A 1 1270 ? 166.625 129.562 54.432  1.00 169.97 ? 1229 VAL A CG1 1 
ATOM   8697 C CG2 . VAL A 1 1270 ? 166.135 131.595 53.061  1.00 169.97 ? 1229 VAL A CG2 1 
ATOM   8698 N N   . ILE A 1 1271 ? 165.366 126.942 52.626  1.00 175.80 ? 1230 ILE A N   1 
ATOM   8699 C CA  . ILE A 1 1271 ? 164.877 125.612 52.965  1.00 175.80 ? 1230 ILE A CA  1 
ATOM   8700 C C   . ILE A 1 1271 ? 165.885 124.944 53.890  1.00 175.80 ? 1230 ILE A C   1 
ATOM   8701 O O   . ILE A 1 1271 ? 167.098 125.114 53.728  1.00 175.80 ? 1230 ILE A O   1 
ATOM   8702 C CB  . ILE A 1 1271 ? 164.648 124.747 51.707  1.00 175.80 ? 1230 ILE A CB  1 
ATOM   8703 C CG1 . ILE A 1 1271 ? 163.949 125.555 50.612  1.00 175.80 ? 1230 ILE A CG1 1 
ATOM   8704 C CG2 . ILE A 1 1271 ? 163.815 123.523 52.051  1.00 175.80 ? 1230 ILE A CG2 1 
ATOM   8705 C CD1 . ILE A 1 1271 ? 162.555 126.001 50.974  1.00 175.80 ? 1230 ILE A CD1 1 
ATOM   8706 N N   . ALA A 1 1272 ? 165.381 124.186 54.861  1.00 175.09 ? 1231 ALA A N   1 
ATOM   8707 C CA  . ALA A 1 1272 ? 166.217 123.487 55.823  1.00 175.09 ? 1231 ALA A CA  1 
ATOM   8708 C C   . ALA A 1 1272 ? 165.806 122.023 55.893  1.00 175.09 ? 1231 ALA A C   1 
ATOM   8709 O O   . ALA A 1 1272 ? 164.685 121.650 55.538  1.00 175.09 ? 1231 ALA A O   1 
ATOM   8710 C CB  . ALA A 1 1272 ? 166.132 124.126 57.217  1.00 175.09 ? 1231 ALA A CB  1 
ATOM   8711 N N   . VAL A 1 1273 ? 166.736 121.192 56.357  1.00 178.99 ? 1232 VAL A N   1 
ATOM   8712 C CA  . VAL A 1 1273 ? 166.543 119.749 56.451  1.00 178.99 ? 1232 VAL A CA  1 
ATOM   8713 C C   . VAL A 1 1273 ? 166.627 119.341 57.915  1.00 178.99 ? 1232 VAL A C   1 
ATOM   8714 O O   . VAL A 1 1273 ? 167.531 119.771 58.640  1.00 178.99 ? 1232 VAL A O   1 
ATOM   8715 C CB  . VAL A 1 1273 ? 167.579 118.990 55.603  1.00 178.99 ? 1232 VAL A CB  1 
ATOM   8716 C CG1 . VAL A 1 1273 ? 167.396 117.487 55.750  1.00 178.99 ? 1232 VAL A CG1 1 
ATOM   8717 C CG2 . VAL A 1 1273 ? 167.477 119.414 54.149  1.00 178.99 ? 1232 VAL A CG2 1 
ATOM   8718 N N   . ILE A 1 1274 ? 165.687 118.505 58.344  1.00 177.42 ? 1233 ILE A N   1 
ATOM   8719 C CA  . ILE A 1 1274 ? 165.520 118.152 59.747  1.00 177.42 ? 1233 ILE A CA  1 
ATOM   8720 C C   . ILE A 1 1274 ? 166.088 116.760 60.046  1.00 177.42 ? 1233 ILE A C   1 
ATOM   8721 O O   . ILE A 1 1274 ? 165.738 116.149 61.056  1.00 177.42 ? 1233 ILE A O   1 
ATOM   8722 C CB  . ILE A 1 1274 ? 164.041 118.269 60.159  1.00 177.42 ? 1233 ILE A CB  1 
ATOM   8723 C CG1 . ILE A 1 1274 ? 163.899 118.480 61.671  1.00 177.42 ? 1233 ILE A CG1 1 
ATOM   8724 C CG2 . ILE A 1 1274 ? 163.225 117.078 59.646  1.00 177.42 ? 1233 ILE A CG2 1 
ATOM   8725 C CD1 . ILE A 1 1274 ? 164.176 119.897 62.113  1.00 177.42 ? 1233 ILE A CD1 1 
ATOM   8726 N N   . ASP A 1 1275 ? 166.991 116.266 59.198  1.00 178.12 ? 1234 ASP A N   1 
ATOM   8727 C CA  . ASP A 1 1275 ? 167.469 114.889 59.288  1.00 178.12 ? 1234 ASP A CA  1 
ATOM   8728 C C   . ASP A 1 1275 ? 168.034 114.541 60.661  1.00 178.12 ? 1234 ASP A C   1 
ATOM   8729 O O   . ASP A 1 1275 ? 169.078 115.064 61.064  1.00 178.12 ? 1234 ASP A O   1 
ATOM   8730 C CB  . ASP A 1 1275 ? 168.534 114.630 58.220  1.00 178.12 ? 1234 ASP A CB  1 
ATOM   8731 C CG  . ASP A 1 1275 ? 168.829 113.155 58.040  1.00 178.12 ? 1234 ASP A CG  1 
ATOM   8732 O OD1 . ASP A 1 1275 ? 168.072 112.325 58.584  1.00 178.12 ? 1234 ASP A OD1 1 
ATOM   8733 O OD2 . ASP A 1 1275 ? 169.818 112.825 57.353  1.00 178.12 ? 1234 ASP A OD2 1 
ATOM   8734 N N   . ASP A 1 1276 ? 167.346 113.644 61.371  1.00 176.22 ? 1235 ASP A N   1 
ATOM   8735 C CA  . ASP A 1 1276 ? 167.815 113.090 62.643  1.00 176.22 ? 1235 ASP A CA  1 
ATOM   8736 C C   . ASP A 1 1276 ? 168.171 114.185 63.647  1.00 176.22 ? 1235 ASP A C   1 
ATOM   8737 O O   . ASP A 1 1276 ? 169.162 114.092 64.375  1.00 176.22 ? 1235 ASP A O   1 
ATOM   8738 C CB  . ASP A 1 1276 ? 169.000 112.149 62.420  1.00 176.22 ? 1235 ASP A CB  1 
ATOM   8739 C CG  . ASP A 1 1276 ? 168.601 110.874 61.705  1.00 176.22 ? 1235 ASP A CG  1 
ATOM   8740 O OD1 . ASP A 1 1276 ? 167.438 110.444 61.859  1.00 176.22 ? 1235 ASP A OD1 1 
ATOM   8741 O OD2 . ASP A 1 1276 ? 169.449 110.302 60.989  1.00 176.22 ? 1235 ASP A OD2 1 
ATOM   8742 N N   . GLY A 1 1277 ? 167.350 115.231 63.693  1.00 174.63 ? 1236 GLY A N   1 
ATOM   8743 C CA  . GLY A 1 1277 ? 167.585 116.301 64.640  1.00 174.63 ? 1236 GLY A CA  1 
ATOM   8744 C C   . GLY A 1 1277 ? 168.729 117.224 64.294  1.00 174.63 ? 1236 GLY A C   1 
ATOM   8745 O O   . GLY A 1 1277 ? 169.165 117.992 65.156  1.00 174.63 ? 1236 GLY A O   1 
ATOM   8746 N N   . LYS A 1 1278 ? 169.231 117.172 63.063  1.00 176.86 ? 1237 LYS A N   1 
ATOM   8747 C CA  . LYS A 1 1278 ? 170.326 118.023 62.625  1.00 176.86 ? 1237 LYS A CA  1 
ATOM   8748 C C   . LYS A 1 1278 ? 169.974 118.649 61.283  1.00 176.86 ? 1237 LYS A C   1 
ATOM   8749 O O   . LYS A 1 1278 ? 169.153 118.128 60.525  1.00 176.86 ? 1237 LYS A O   1 
ATOM   8750 C CB  . LYS A 1 1278 ? 171.642 117.243 62.505  1.00 176.86 ? 1237 LYS A CB  1 
ATOM   8751 C CG  . LYS A 1 1278 ? 172.396 117.068 63.815  1.00 176.86 ? 1237 LYS A CG  1 
ATOM   8752 C CD  . LYS A 1 1278 ? 171.903 115.855 64.586  1.00 176.86 ? 1237 LYS A CD  1 
ATOM   8753 C CE  . LYS A 1 1278 ? 172.334 114.561 63.917  1.00 176.86 ? 1237 LYS A CE  1 
ATOM   8754 N NZ  . LYS A 1 1278 ? 171.913 113.368 64.702  1.00 176.86 ? 1237 LYS A NZ  1 
ATOM   8755 N N   . VAL A 1 1279 ? 170.606 119.783 60.999  1.00 178.97 ? 1238 VAL A N   1 
ATOM   8756 C CA  . VAL A 1 1279 ? 170.428 120.473 59.728  1.00 178.97 ? 1238 VAL A CA  1 
ATOM   8757 C C   . VAL A 1 1279 ? 171.421 119.910 58.719  1.00 178.97 ? 1238 VAL A C   1 
ATOM   8758 O O   . VAL A 1 1279 ? 172.605 119.724 59.029  1.00 178.97 ? 1238 VAL A O   1 
ATOM   8759 C CB  . VAL A 1 1279 ? 170.589 121.996 59.897  1.00 178.97 ? 1238 VAL A CB  1 
ATOM   8760 C CG1 . VAL A 1 1279 ? 171.990 122.359 60.374  1.00 178.97 ? 1238 VAL A CG1 1 
ATOM   8761 C CG2 . VAL A 1 1279 ? 170.262 122.710 58.593  1.00 178.97 ? 1238 VAL A CG2 1 
ATOM   8762 N N   . ALA A 1 1280 ? 170.932 119.597 57.520  1.00 183.22 ? 1239 ALA A N   1 
ATOM   8763 C CA  . ALA A 1 1280 ? 171.761 119.007 56.475  1.00 183.22 ? 1239 ALA A CA  1 
ATOM   8764 C C   . ALA A 1 1280 ? 172.079 120.002 55.363  1.00 183.22 ? 1239 ALA A C   1 
ATOM   8765 O O   . ALA A 1 1280 ? 173.251 120.247 55.063  1.00 183.22 ? 1239 ALA A O   1 
ATOM   8766 C CB  . ALA A 1 1280 ? 171.074 117.762 55.900  1.00 183.22 ? 1239 ALA A CB  1 
ATOM   8767 N N   . GLU A 1 1281 ? 171.053 120.581 54.747  1.00 189.81 ? 1240 GLU A N   1 
ATOM   8768 C CA  . GLU A 1 1281 ? 171.232 121.515 53.643  1.00 189.81 ? 1240 GLU A CA  1 
ATOM   8769 C C   . GLU A 1 1281 ? 170.442 122.783 53.925  1.00 189.81 ? 1240 GLU A C   1 
ATOM   8770 O O   . GLU A 1 1281 ? 169.253 122.719 54.250  1.00 189.81 ? 1240 GLU A O   1 
ATOM   8771 C CB  . GLU A 1 1281 ? 170.785 120.892 52.314  1.00 189.81 ? 1240 GLU A CB  1 
ATOM   8772 C CG  . GLU A 1 1281 ? 171.500 119.592 51.967  1.00 189.81 ? 1240 GLU A CG  1 
ATOM   8773 C CD  . GLU A 1 1281 ? 171.220 119.124 50.552  1.00 189.81 ? 1240 GLU A CD  1 
ATOM   8774 O OE1 . GLU A 1 1281 ? 170.507 119.839 49.816  1.00 189.81 ? 1240 GLU A OE1 1 
ATOM   8775 O OE2 . GLU A 1 1281 ? 171.713 118.040 50.172  1.00 189.81 ? 1240 GLU A OE2 1 
ATOM   8776 N N   . GLN A 1 1282 ? 171.105 123.930 53.800  1.00 186.71 ? 1241 GLN A N   1 
ATOM   8777 C CA  . GLN A 1 1282 ? 170.490 125.232 54.020  1.00 186.71 ? 1241 GLN A CA  1 
ATOM   8778 C C   . GLN A 1 1282 ? 170.660 126.084 52.772  1.00 186.71 ? 1241 GLN A C   1 
ATOM   8779 O O   . GLN A 1 1282 ? 171.784 126.279 52.297  1.00 186.71 ? 1241 GLN A O   1 
ATOM   8780 C CB  . GLN A 1 1282 ? 171.108 125.934 55.233  1.00 186.71 ? 1241 GLN A CB  1 
ATOM   8781 C CG  . GLN A 1 1282 ? 170.576 127.338 55.471  1.00 186.71 ? 1241 GLN A CG  1 
ATOM   8782 C CD  . GLN A 1 1282 ? 171.053 127.927 56.783  1.00 186.71 ? 1241 GLN A CD  1 
ATOM   8783 O OE1 . GLN A 1 1282 ? 171.729 127.260 57.566  1.00 186.71 ? 1241 GLN A OE1 1 
ATOM   8784 N NE2 . GLN A 1 1282 ? 170.703 129.184 57.030  1.00 186.71 ? 1241 GLN A NE2 1 
ATOM   8785 N N   . GLY A 1 1283 ? 169.556 126.584 52.250  1.00 186.33 ? 1242 GLY A N   1 
ATOM   8786 C CA  . GLY A 1 1283 ? 169.586 127.407 51.056  1.00 186.33 ? 1242 GLY A CA  1 
ATOM   8787 C C   . GLY A 1 1283 ? 168.333 127.189 50.232  1.00 186.33 ? 1242 GLY A C   1 
ATOM   8788 O O   . GLY A 1 1283 ? 167.461 126.396 50.577  1.00 186.33 ? 1242 GLY A O   1 
ATOM   8789 N N   . SER A 1 1284 ? 168.268 127.919 49.122  1.00 189.67 ? 1243 SER A N   1 
ATOM   8790 C CA  . SER A 1 1284 ? 167.122 127.828 48.230  1.00 189.67 ? 1243 SER A CA  1 
ATOM   8791 C C   . SER A 1 1284 ? 167.048 126.450 47.584  1.00 189.67 ? 1243 SER A C   1 
ATOM   8792 O O   . SER A 1 1284 ? 168.068 125.802 47.331  1.00 189.67 ? 1243 SER A O   1 
ATOM   8793 C CB  . SER A 1 1284 ? 167.194 128.906 47.152  1.00 189.67 ? 1243 SER A CB  1 
ATOM   8794 O OG  . SER A 1 1284 ? 166.231 128.675 46.139  1.00 189.67 ? 1243 SER A OG  1 
ATOM   8795 N N   . HIS A 1 1285 ? 165.817 126.001 47.324  1.00 191.81 ? 1244 HIS A N   1 
ATOM   8796 C CA  . HIS A 1 1285 ? 165.623 124.686 46.725  1.00 191.81 ? 1244 HIS A CA  1 
ATOM   8797 C C   . HIS A 1 1285 ? 166.247 124.612 45.337  1.00 191.81 ? 1244 HIS A C   1 
ATOM   8798 O O   . HIS A 1 1285 ? 166.936 123.640 45.009  1.00 191.81 ? 1244 HIS A O   1 
ATOM   8799 C CB  . HIS A 1 1285 ? 164.133 124.354 46.661  1.00 191.81 ? 1244 HIS A CB  1 
ATOM   8800 C CG  . HIS A 1 1285 ? 163.841 122.968 46.174  1.00 191.81 ? 1244 HIS A CG  1 
ATOM   8801 N ND1 . HIS A 1 1285 ? 163.472 121.945 47.020  1.00 191.81 ? 1244 HIS A ND1 1 
ATOM   8802 C CD2 . HIS A 1 1285 ? 163.861 122.438 44.929  1.00 191.81 ? 1244 HIS A CD2 1 
ATOM   8803 C CE1 . HIS A 1 1285 ? 163.279 120.843 46.318  1.00 191.81 ? 1244 HIS A CE1 1 
ATOM   8804 N NE2 . HIS A 1 1285 ? 163.508 121.116 45.045  1.00 191.81 ? 1244 HIS A NE2 1 
ATOM   8805 N N   . SER A 1 1286 ? 166.024 125.634 44.509  1.00 194.82 ? 1245 SER A N   1 
ATOM   8806 C CA  . SER A 1 1286 ? 166.668 125.676 43.200  1.00 194.82 ? 1245 SER A CA  1 
ATOM   8807 C C   . SER A 1 1286 ? 168.179 125.812 43.334  1.00 194.82 ? 1245 SER A C   1 
ATOM   8808 O O   . SER A 1 1286 ? 168.933 125.172 42.593  1.00 194.82 ? 1245 SER A O   1 
ATOM   8809 C CB  . SER A 1 1286 ? 166.100 126.825 42.370  1.00 194.82 ? 1245 SER A CB  1 
ATOM   8810 O OG  . SER A 1 1286 ? 164.684 126.844 42.429  1.00 194.82 ? 1245 SER A OG  1 
ATOM   8811 N N   . HIS A 1 1287 ? 168.636 126.645 44.272  1.00 194.24 ? 1246 HIS A N   1 
ATOM   8812 C CA  . HIS A 1 1287 ? 170.068 126.864 44.437  1.00 194.24 ? 1246 HIS A CA  1 
ATOM   8813 C C   . HIS A 1 1287 ? 170.784 125.585 44.855  1.00 194.24 ? 1246 HIS A C   1 
ATOM   8814 O O   . HIS A 1 1287 ? 171.860 125.271 44.335  1.00 194.24 ? 1246 HIS A O   1 
ATOM   8815 C CB  . HIS A 1 1287 ? 170.314 127.973 45.459  1.00 194.24 ? 1246 HIS A CB  1 
ATOM   8816 C CG  . HIS A 1 1287 ? 171.715 128.008 45.987  1.00 194.24 ? 1246 HIS A CG  1 
ATOM   8817 N ND1 . HIS A 1 1287 ? 172.017 127.765 47.309  1.00 194.24 ? 1246 HIS A ND1 1 
ATOM   8818 C CD2 . HIS A 1 1287 ? 172.894 128.258 45.370  1.00 194.24 ? 1246 HIS A CD2 1 
ATOM   8819 C CE1 . HIS A 1 1287 ? 173.323 127.863 47.484  1.00 194.24 ? 1246 HIS A CE1 1 
ATOM   8820 N NE2 . HIS A 1 1287 ? 173.879 128.162 46.323  1.00 194.24 ? 1246 HIS A NE2 1 
ATOM   8821 N N   . LEU A 1 1288 ? 170.202 124.834 45.789  1.00 196.78 ? 1247 LEU A N   1 
ATOM   8822 C CA  . LEU A 1 1288 ? 170.836 123.611 46.264  1.00 196.78 ? 1247 LEU A CA  1 
ATOM   8823 C C   . LEU A 1 1288 ? 170.498 122.394 45.415  1.00 196.78 ? 1247 LEU A C   1 
ATOM   8824 O O   . LEU A 1 1288 ? 171.110 121.338 45.608  1.00 196.78 ? 1247 LEU A O   1 
ATOM   8825 C CB  . LEU A 1 1288 ? 170.443 123.341 47.716  1.00 196.78 ? 1247 LEU A CB  1 
ATOM   8826 C CG  . LEU A 1 1288 ? 170.876 124.387 48.744  1.00 196.78 ? 1247 LEU A CG  1 
ATOM   8827 C CD1 . LEU A 1 1288 ? 170.450 123.954 50.136  1.00 196.78 ? 1247 LEU A CD1 1 
ATOM   8828 C CD2 . LEU A 1 1288 ? 172.377 124.633 48.683  1.00 196.78 ? 1247 LEU A CD2 1 
ATOM   8829 N N   . LEU A 1 1289 ? 169.542 122.505 44.493  1.00 197.93 ? 1248 LEU A N   1 
ATOM   8830 C CA  . LEU A 1 1289 ? 169.251 121.398 43.593  1.00 197.93 ? 1248 LEU A CA  1 
ATOM   8831 C C   . LEU A 1 1289 ? 170.289 121.280 42.485  1.00 197.93 ? 1248 LEU A C   1 
ATOM   8832 O O   . LEU A 1 1289 ? 170.615 120.165 42.061  1.00 197.93 ? 1248 LEU A O   1 
ATOM   8833 C CB  . LEU A 1 1289 ? 167.851 121.562 42.997  1.00 197.93 ? 1248 LEU A CB  1 
ATOM   8834 C CG  . LEU A 1 1289 ? 167.382 120.495 42.006  1.00 197.93 ? 1248 LEU A CG  1 
ATOM   8835 C CD1 . LEU A 1 1289 ? 167.120 119.178 42.719  1.00 197.93 ? 1248 LEU A CD1 1 
ATOM   8836 C CD2 . LEU A 1 1289 ? 166.137 120.962 41.269  1.00 197.93 ? 1248 LEU A CD2 1 
ATOM   8837 N N   . LYS A 1 1290 ? 170.817 122.410 42.009  1.00 200.83 ? 1249 LYS A N   1 
ATOM   8838 C CA  . LYS A 1 1290 ? 171.803 122.379 40.934  1.00 200.83 ? 1249 LYS A CA  1 
ATOM   8839 C C   . LYS A 1 1290 ? 173.103 121.729 41.396  1.00 200.83 ? 1249 LYS A C   1 
ATOM   8840 O O   . LYS A 1 1290 ? 173.622 120.820 40.736  1.00 200.83 ? 1249 LYS A O   1 
ATOM   8841 C CB  . LYS A 1 1290 ? 172.050 123.799 40.419  1.00 200.83 ? 1249 LYS A CB  1 
ATOM   8842 C CG  . LYS A 1 1290 ? 173.052 123.911 39.274  1.00 200.83 ? 1249 LYS A CG  1 
ATOM   8843 C CD  . LYS A 1 1290 ? 174.448 124.258 39.775  1.00 200.83 ? 1249 LYS A CD  1 
ATOM   8844 C CE  . LYS A 1 1290 ? 174.508 125.684 40.293  1.00 200.83 ? 1249 LYS A CE  1 
ATOM   8845 N NZ  . LYS A 1 1290 ? 175.869 126.041 40.777  1.00 200.83 ? 1249 LYS A NZ  1 
ATOM   8846 N N   . ASN A 1 1291 ? 173.641 122.177 42.525  1.00 201.45 ? 1250 ASN A N   1 
ATOM   8847 C CA  . ASN A 1 1291 ? 174.889 121.635 43.037  1.00 201.45 ? 1250 ASN A CA  1 
ATOM   8848 C C   . ASN A 1 1291 ? 174.612 120.486 44.004  1.00 201.45 ? 1250 ASN A C   1 
ATOM   8849 O O   . ASN A 1 1291 ? 173.476 120.254 44.424  1.00 201.45 ? 1250 ASN A O   1 
ATOM   8850 C CB  . ASN A 1 1291 ? 175.717 122.728 43.713  1.00 201.45 ? 1250 ASN A CB  1 
ATOM   8851 C CG  . ASN A 1 1291 ? 174.919 123.528 44.716  1.00 201.45 ? 1250 ASN A CG  1 
ATOM   8852 O OD1 . ASN A 1 1291 ? 173.730 123.283 44.914  1.00 201.45 ? 1250 ASN A OD1 1 
ATOM   8853 N ND2 . ASN A 1 1291 ? 175.567 124.495 45.355  1.00 201.45 ? 1250 ASN A ND2 1 
ATOM   8854 N N   . HIS A 1 1292 ? 175.687 119.773 44.365  1.00 204.28 ? 1251 HIS A N   1 
ATOM   8855 C CA  . HIS A 1 1292 ? 175.669 118.522 45.122  1.00 204.28 ? 1251 HIS A CA  1 
ATOM   8856 C C   . HIS A 1 1292 ? 174.497 117.653 44.677  1.00 204.28 ? 1251 HIS A C   1 
ATOM   8857 O O   . HIS A 1 1292 ? 173.520 117.491 45.420  1.00 204.28 ? 1251 HIS A O   1 
ATOM   8858 C CB  . HIS A 1 1292 ? 175.633 118.772 46.637  1.00 204.28 ? 1251 HIS A CB  1 
ATOM   8859 C CG  . HIS A 1 1292 ? 174.570 119.727 47.084  1.00 204.28 ? 1251 HIS A CG  1 
ATOM   8860 N ND1 . HIS A 1 1292 ? 174.727 121.095 47.028  1.00 204.28 ? 1251 HIS A ND1 1 
ATOM   8861 C CD2 . HIS A 1 1292 ? 173.341 119.511 47.610  1.00 204.28 ? 1251 HIS A CD2 1 
ATOM   8862 C CE1 . HIS A 1 1292 ? 173.637 121.680 47.492  1.00 204.28 ? 1251 HIS A CE1 1 
ATOM   8863 N NE2 . HIS A 1 1292 ? 172.780 120.741 47.851  1.00 204.28 ? 1251 HIS A NE2 1 
ATOM   8864 N N   . PRO A 1 1293 ? 174.553 117.091 43.469  1.00 207.51 ? 1252 PRO A N   1 
ATOM   8865 C CA  . PRO A 1 1293 ? 173.420 116.313 42.953  1.00 207.51 ? 1252 PRO A CA  1 
ATOM   8866 C C   . PRO A 1 1293 ? 173.127 115.102 43.823  1.00 207.51 ? 1252 PRO A C   1 
ATOM   8867 O O   . PRO A 1 1293 ? 173.889 114.733 44.719  1.00 207.51 ? 1252 PRO A O   1 
ATOM   8868 C CB  . PRO A 1 1293 ? 173.876 115.898 41.549  1.00 207.51 ? 1252 PRO A CB  1 
ATOM   8869 C CG  . PRO A 1 1293 ? 175.001 116.830 41.210  1.00 207.51 ? 1252 PRO A CG  1 
ATOM   8870 C CD  . PRO A 1 1293 ? 175.670 117.138 42.512  1.00 207.51 ? 1252 PRO A CD  1 
ATOM   8871 N N   . ASP A 1 1294 ? 171.983 114.476 43.538  1.00 205.96 ? 1253 ASP A N   1 
ATOM   8872 C CA  . ASP A 1 1294 ? 171.470 113.359 44.333  1.00 205.96 ? 1253 ASP A CA  1 
ATOM   8873 C C   . ASP A 1 1294 ? 171.249 113.784 45.783  1.00 205.96 ? 1253 ASP A C   1 
ATOM   8874 O O   . ASP A 1 1294 ? 171.409 112.993 46.715  1.00 205.96 ? 1253 ASP A O   1 
ATOM   8875 C CB  . ASP A 1 1294 ? 172.397 112.144 44.252  1.00 205.96 ? 1253 ASP A CB  1 
ATOM   8876 C CG  . ASP A 1 1294 ? 172.669 111.713 42.825  1.00 205.96 ? 1253 ASP A CG  1 
ATOM   8877 O OD1 . ASP A 1 1294 ? 171.726 111.245 42.153  1.00 205.96 ? 1253 ASP A OD1 1 
ATOM   8878 O OD2 . ASP A 1 1294 ? 173.827 111.845 42.374  1.00 205.96 ? 1253 ASP A OD2 1 
ATOM   8879 N N   . GLY A 1 1295 ? 170.873 115.048 45.970  1.00 201.37 ? 1254 GLY A N   1 
ATOM   8880 C CA  . GLY A 1 1295 ? 170.647 115.586 47.292  1.00 201.37 ? 1254 GLY A CA  1 
ATOM   8881 C C   . GLY A 1 1295 ? 169.322 115.146 47.878  1.00 201.37 ? 1254 GLY A C   1 
ATOM   8882 O O   . GLY A 1 1295 ? 168.526 114.439 47.259  1.00 201.37 ? 1254 GLY A O   1 
ATOM   8883 N N   . ILE A 1 1296 ? 169.088 115.582 49.117  1.00 198.34 ? 1255 ILE A N   1 
ATOM   8884 C CA  . ILE A 1 1296 ? 167.860 115.212 49.812  1.00 198.34 ? 1255 ILE A CA  1 
ATOM   8885 C C   . ILE A 1 1296 ? 166.641 115.832 49.135  1.00 198.34 ? 1255 ILE A C   1 
ATOM   8886 O O   . ILE A 1 1296 ? 165.549 115.252 49.160  1.00 198.34 ? 1255 ILE A O   1 
ATOM   8887 C CB  . ILE A 1 1296 ? 167.957 115.597 51.299  1.00 198.34 ? 1255 ILE A CB  1 
ATOM   8888 C CG1 . ILE A 1 1296 ? 166.805 114.976 52.091  1.00 198.34 ? 1255 ILE A CG1 1 
ATOM   8889 C CG2 . ILE A 1 1296 ? 168.003 117.107 51.466  1.00 198.34 ? 1255 ILE A CG2 1 
ATOM   8890 C CD1 . ILE A 1 1296 ? 166.846 113.464 52.140  1.00 198.34 ? 1255 ILE A CD1 1 
ATOM   8891 N N   . TYR A 1 1297 ? 166.799 117.010 48.524  1.00 196.21 ? 1256 TYR A N   1 
ATOM   8892 C CA  . TYR A 1 1297 ? 165.713 117.575 47.729  1.00 196.21 ? 1256 TYR A CA  1 
ATOM   8893 C C   . TYR A 1 1297 ? 165.382 116.676 46.546  1.00 196.21 ? 1256 TYR A C   1 
ATOM   8894 O O   . TYR A 1 1297 ? 164.207 116.415 46.259  1.00 196.21 ? 1256 TYR A O   1 
ATOM   8895 C CB  . TYR A 1 1297 ? 166.085 118.975 47.241  1.00 196.21 ? 1256 TYR A CB  1 
ATOM   8896 C CG  . TYR A 1 1297 ? 166.402 119.958 48.343  1.00 196.21 ? 1256 TYR A CG  1 
ATOM   8897 C CD1 . TYR A 1 1297 ? 165.502 120.195 49.372  1.00 196.21 ? 1256 TYR A CD1 1 
ATOM   8898 C CD2 . TYR A 1 1297 ? 167.599 120.661 48.346  1.00 196.21 ? 1256 TYR A CD2 1 
ATOM   8899 C CE1 . TYR A 1 1297 ? 165.788 121.097 50.378  1.00 196.21 ? 1256 TYR A CE1 1 
ATOM   8900 C CE2 . TYR A 1 1297 ? 167.894 121.565 49.347  1.00 196.21 ? 1256 TYR A CE2 1 
ATOM   8901 C CZ  . TYR A 1 1297 ? 166.986 121.780 50.360  1.00 196.21 ? 1256 TYR A CZ  1 
ATOM   8902 O OH  . TYR A 1 1297 ? 167.278 122.681 51.358  1.00 196.21 ? 1256 TYR A OH  1 
ATOM   8903 N N   . ALA A 1 1298 ? 166.410 116.191 45.846  1.00 202.83 ? 1257 ALA A N   1 
ATOM   8904 C CA  . ALA A 1 1298 ? 166.194 115.264 44.745  1.00 202.83 ? 1257 ALA A CA  1 
ATOM   8905 C C   . ALA A 1 1298 ? 165.525 113.979 45.205  1.00 202.83 ? 1257 ALA A C   1 
ATOM   8906 O O   . ALA A 1 1298 ? 164.781 113.374 44.429  1.00 202.83 ? 1257 ALA A O   1 
ATOM   8907 C CB  . ALA A 1 1298 ? 167.520 114.947 44.054  1.00 202.83 ? 1257 ALA A CB  1 
ATOM   8908 N N   . ARG A 1 1299 ? 165.758 113.559 46.452  1.00 202.14 ? 1258 ARG A N   1 
ATOM   8909 C CA  . ARG A 1 1299 ? 165.104 112.360 46.963  1.00 202.14 ? 1258 ARG A CA  1 
ATOM   8910 C C   . ARG A 1 1299 ? 163.588 112.518 46.972  1.00 202.14 ? 1258 ARG A C   1 
ATOM   8911 O O   . ARG A 1 1299 ? 162.863 111.667 46.443  1.00 202.14 ? 1258 ARG A O   1 
ATOM   8912 C CB  . ARG A 1 1299 ? 165.617 112.040 48.367  1.00 202.14 ? 1258 ARG A CB  1 
ATOM   8913 C CG  . ARG A 1 1299 ? 166.748 111.018 48.420  1.00 202.14 ? 1258 ARG A CG  1 
ATOM   8914 C CD  . ARG A 1 1299 ? 167.769 111.236 47.315  1.00 202.14 ? 1258 ARG A CD  1 
ATOM   8915 N NE  . ARG A 1 1299 ? 168.755 110.164 47.261  1.00 202.14 ? 1258 ARG A NE  1 
ATOM   8916 C CZ  . ARG A 1 1299 ? 169.582 109.960 46.245  1.00 202.14 ? 1258 ARG A CZ  1 
ATOM   8917 N NH1 . ARG A 1 1299 ? 169.560 110.731 45.171  1.00 202.14 ? 1258 ARG A NH1 1 
ATOM   8918 N NH2 . ARG A 1 1299 ? 170.450 108.954 46.306  1.00 202.14 ? 1258 ARG A NH2 1 
ATOM   8919 N N   . MET A 1 1300 ? 163.088 113.612 47.552  1.00 204.50 ? 1259 MET A N   1 
ATOM   8920 C CA  . MET A 1 1300 ? 161.644 113.807 47.596  1.00 204.50 ? 1259 MET A CA  1 
ATOM   8921 C C   . MET A 1 1300 ? 161.086 114.195 46.233  1.00 204.50 ? 1259 MET A C   1 
ATOM   8922 O O   . MET A 1 1300 ? 159.916 113.915 45.950  1.00 204.50 ? 1259 MET A O   1 
ATOM   8923 C CB  . MET A 1 1300 ? 161.273 114.848 48.660  1.00 204.50 ? 1259 MET A CB  1 
ATOM   8924 C CG  . MET A 1 1300 ? 162.015 116.178 48.594  1.00 204.50 ? 1259 MET A CG  1 
ATOM   8925 S SD  . MET A 1 1300 ? 161.454 117.273 47.275  1.00 204.50 ? 1259 MET A SD  1 
ATOM   8926 C CE  . MET A 1 1300 ? 160.122 118.140 48.101  1.00 204.50 ? 1259 MET A CE  1 
ATOM   8927 N N   . ILE A 1 1301 ? 161.895 114.825 45.376  1.00 205.50 ? 1260 ILE A N   1 
ATOM   8928 C CA  . ILE A 1 1301 ? 161.452 115.070 44.006  1.00 205.50 ? 1260 ILE A CA  1 
ATOM   8929 C C   . ILE A 1 1301 ? 161.220 113.751 43.278  1.00 205.50 ? 1260 ILE A C   1 
ATOM   8930 O O   . ILE A 1 1301 ? 160.193 113.564 42.614  1.00 205.50 ? 1260 ILE A O   1 
ATOM   8931 C CB  . ILE A 1 1301 ? 162.464 115.959 43.261  1.00 205.50 ? 1260 ILE A CB  1 
ATOM   8932 C CG1 . ILE A 1 1301 ? 162.458 117.377 43.836  1.00 205.50 ? 1260 ILE A CG1 1 
ATOM   8933 C CG2 . ILE A 1 1301 ? 162.157 115.989 41.771  1.00 205.50 ? 1260 ILE A CG2 1 
ATOM   8934 C CD1 . ILE A 1 1301 ? 163.437 118.313 43.162  1.00 205.50 ? 1260 ILE A CD1 1 
ATOM   8935 N N   . GLN A 1 1302 ? 162.163 112.813 43.399  1.00 205.63 ? 1261 GLN A N   1 
ATOM   8936 C CA  . GLN A 1 1302 ? 162.004 111.504 42.775  1.00 205.63 ? 1261 GLN A CA  1 
ATOM   8937 C C   . GLN A 1 1302 ? 160.834 110.743 43.384  1.00 205.63 ? 1261 GLN A C   1 
ATOM   8938 O O   . GLN A 1 1302 ? 160.076 110.077 42.668  1.00 205.63 ? 1261 GLN A O   1 
ATOM   8939 C CB  . GLN A 1 1302 ? 163.300 110.703 42.910  1.00 205.63 ? 1261 GLN A CB  1 
ATOM   8940 C CG  . GLN A 1 1302 ? 163.161 109.224 42.595  1.00 205.63 ? 1261 GLN A CG  1 
ATOM   8941 C CD  . GLN A 1 1302 ? 164.250 108.390 43.241  1.00 205.63 ? 1261 GLN A CD  1 
ATOM   8942 O OE1 . GLN A 1 1302 ? 164.403 108.389 44.462  1.00 205.63 ? 1261 GLN A OE1 1 
ATOM   8943 N NE2 . GLN A 1 1302 ? 165.013 107.676 42.422  1.00 205.63 ? 1261 GLN A NE2 1 
ATOM   8944 N N   . LEU A 1 1303 ? 160.672 110.827 44.706  1.00 205.49 ? 1262 LEU A N   1 
ATOM   8945 C CA  . LEU A 1 1303 ? 159.554 110.152 45.357  1.00 205.49 ? 1262 LEU A CA  1 
ATOM   8946 C C   . LEU A 1 1303 ? 158.218 110.705 44.874  1.00 205.49 ? 1262 LEU A C   1 
ATOM   8947 O O   . LEU A 1 1303 ? 157.262 109.949 44.668  1.00 205.49 ? 1262 LEU A O   1 
ATOM   8948 C CB  . LEU A 1 1303 ? 159.674 110.285 46.875  1.00 205.49 ? 1262 LEU A CB  1 
ATOM   8949 C CG  . LEU A 1 1303 ? 158.648 109.519 47.711  1.00 205.49 ? 1262 LEU A CG  1 
ATOM   8950 C CD1 . LEU A 1 1303 ? 158.841 108.021 47.551  1.00 205.49 ? 1262 LEU A CD1 1 
ATOM   8951 C CD2 . LEU A 1 1303 ? 158.739 109.922 49.175  1.00 205.49 ? 1262 LEU A CD2 1 
ATOM   8952 N N   . GLN A 1 1304 ? 158.133 112.024 44.684  1.00 203.84 ? 1263 GLN A N   1 
ATOM   8953 C CA  . GLN A 1 1304 ? 156.897 112.649 44.232  1.00 203.84 ? 1263 GLN A CA  1 
ATOM   8954 C C   . GLN A 1 1304 ? 156.596 112.384 42.763  1.00 203.84 ? 1263 GLN A C   1 
ATOM   8955 O O   . GLN A 1 1304 ? 155.475 112.659 42.322  1.00 203.84 ? 1263 GLN A O   1 
ATOM   8956 C CB  . GLN A 1 1304 ? 156.954 114.157 44.480  1.00 203.84 ? 1263 GLN A CB  1 
ATOM   8957 C CG  . GLN A 1 1304 ? 156.507 114.572 45.871  1.00 203.84 ? 1263 GLN A CG  1 
ATOM   8958 C CD  . GLN A 1 1304 ? 157.040 115.932 46.269  1.00 203.84 ? 1263 GLN A CD  1 
ATOM   8959 O OE1 . GLN A 1 1304 ? 157.943 116.469 45.626  1.00 203.84 ? 1263 GLN A OE1 1 
ATOM   8960 N NE2 . GLN A 1 1304 ? 156.483 116.499 47.332  1.00 203.84 ? 1263 GLN A NE2 1 
ATOM   8961 N N   . ARG A 1 1305 ? 157.556 111.870 42.000  1.00 206.27 ? 1264 ARG A N   1 
ATOM   8962 C CA  . ARG A 1 1305 ? 157.338 111.584 40.586  1.00 206.27 ? 1264 ARG A CA  1 
ATOM   8963 C C   . ARG A 1 1305 ? 156.302 110.480 40.405  1.00 206.27 ? 1264 ARG A C   1 
ATOM   8964 O O   . ARG A 1 1305 ? 155.126 110.753 40.167  1.00 206.27 ? 1264 ARG A O   1 
ATOM   8965 C CB  . ARG A 1 1305 ? 158.651 111.187 39.907  1.00 206.27 ? 1264 ARG A CB  1 
ATOM   8966 C CG  . ARG A 1 1305 ? 159.599 112.344 39.648  1.00 206.27 ? 1264 ARG A CG  1 
ATOM   8967 C CD  . ARG A 1 1305 ? 160.979 111.842 39.258  1.00 206.27 ? 1264 ARG A CD  1 
ATOM   8968 N NE  . ARG A 1 1305 ? 162.031 112.790 39.607  1.00 206.27 ? 1264 ARG A NE  1 
ATOM   8969 C CZ  . ARG A 1 1305 ? 163.320 112.486 39.671  1.00 206.27 ? 1264 ARG A CZ  1 
ATOM   8970 N NH1 . ARG A 1 1305 ? 163.756 111.264 39.415  1.00 206.27 ? 1264 ARG A NH1 1 
ATOM   8971 N NH2 . ARG A 1 1305 ? 164.194 113.433 40.001  1.00 206.27 ? 1264 ARG A NH2 1 
HETATM 8972 C C01 . BLD B 2 .    ? 107.013 116.860 111.578 1.00 45.72  ? 1301 BLD A C01 1 
HETATM 8973 C C02 . BLD B 2 .    ? 106.864 117.887 110.468 1.00 45.72  ? 1301 BLD A C02 1 
HETATM 8974 O O02 . BLD B 2 .    ? 108.150 118.214 109.932 1.00 45.72  ? 1301 BLD A O02 1 
HETATM 8975 C C03 . BLD B 2 .    ? 105.967 117.339 109.379 1.00 45.72  ? 1301 BLD A C03 1 
HETATM 8976 O O03 . BLD B 2 .    ? 106.530 116.143 108.832 1.00 45.72  ? 1301 BLD A O03 1 
HETATM 8977 C C04 . BLD B 2 .    ? 104.589 117.049 109.943 1.00 45.72  ? 1301 BLD A C04 1 
HETATM 8978 C C05 . BLD B 2 .    ? 104.609 116.046 111.107 1.00 45.72  ? 1301 BLD A C05 1 
HETATM 8979 C C06 . BLD B 2 .    ? 103.206 116.000 111.666 1.00 45.72  ? 1301 BLD A C06 1 
HETATM 8980 O O06 . BLD B 2 .    ? 102.392 116.866 111.481 1.00 45.72  ? 1301 BLD A O06 1 
HETATM 8981 C C07 . BLD B 2 .    ? 103.968 113.872 112.424 1.00 45.72  ? 1301 BLD A C07 1 
HETATM 8982 O O07 . BLD B 2 .    ? 102.935 114.873 112.326 1.00 45.72  ? 1301 BLD A O07 1 
HETATM 8983 C C08 . BLD B 2 .    ? 104.920 114.270 113.531 1.00 45.72  ? 1301 BLD A C08 1 
HETATM 8984 C C09 . BLD B 2 .    ? 106.094 115.143 113.051 1.00 45.72  ? 1301 BLD A C09 1 
HETATM 8985 C C10 . BLD B 2 .    ? 105.696 116.357 112.186 1.00 45.72  ? 1301 BLD A C10 1 
HETATM 8986 C C11 . BLD B 2 .    ? 106.988 115.547 114.229 1.00 45.72  ? 1301 BLD A C11 1 
HETATM 8987 C C12 . BLD B 2 .    ? 107.460 114.326 114.994 1.00 45.72  ? 1301 BLD A C12 1 
HETATM 8988 C C13 . BLD B 2 .    ? 106.294 113.498 115.536 1.00 45.72  ? 1301 BLD A C13 1 
HETATM 8989 C C14 . BLD B 2 .    ? 105.437 113.061 114.314 1.00 45.72  ? 1301 BLD A C14 1 
HETATM 8990 C C15 . BLD B 2 .    ? 104.415 112.119 114.949 1.00 45.72  ? 1301 BLD A C15 1 
HETATM 8991 C C16 . BLD B 2 .    ? 105.240 111.352 115.989 1.00 45.72  ? 1301 BLD A C16 1 
HETATM 8992 C C17 . BLD B 2 .    ? 106.609 112.080 116.101 1.00 45.72  ? 1301 BLD A C17 1 
HETATM 8993 C C18 . BLD B 2 .    ? 105.476 114.309 116.554 1.00 45.72  ? 1301 BLD A C18 1 
HETATM 8994 C C19 . BLD B 2 .    ? 105.163 117.462 113.104 1.00 45.72  ? 1301 BLD A C19 1 
HETATM 8995 C C20 . BLD B 2 .    ? 107.248 111.904 117.494 1.00 45.72  ? 1301 BLD A C20 1 
HETATM 8996 C C21 . BLD B 2 .    ? 108.545 112.685 117.671 1.00 45.72  ? 1301 BLD A C21 1 
HETATM 8997 C C22 . BLD B 2 .    ? 107.456 110.411 117.793 1.00 45.72  ? 1301 BLD A C22 1 
HETATM 8998 O O22 . BLD B 2 .    ? 108.242 109.839 116.750 1.00 45.72  ? 1301 BLD A O22 1 
HETATM 8999 C C23 . BLD B 2 .    ? 108.156 110.172 119.142 1.00 45.72  ? 1301 BLD A C23 1 
HETATM 9000 O O23 . BLD B 2 .    ? 109.028 109.051 119.031 1.00 45.72  ? 1301 BLD A O23 1 
HETATM 9001 C C24 . BLD B 2 .    ? 107.139 109.921 120.270 1.00 45.72  ? 1301 BLD A C24 1 
HETATM 9002 C C25 . BLD B 2 .    ? 106.576 111.221 120.884 1.00 45.72  ? 1301 BLD A C25 1 
HETATM 9003 C C26 . BLD B 2 .    ? 105.310 110.979 121.687 1.00 45.72  ? 1301 BLD A C26 1 
HETATM 9004 C C27 . BLD B 2 .    ? 107.607 111.948 121.733 1.00 45.72  ? 1301 BLD A C27 1 
HETATM 9005 C C28 . BLD B 2 .    ? 107.706 108.972 121.339 1.00 45.72  ? 1301 BLD A C28 1 
# 
