data_9JTC
# 
_entry.id   9JTC 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JTC         pdb_00009jtc 10.2210/pdb9jtc/pdb 
WWPDB D_1300052179 ?            ?                   
EMDB  EMD-61794    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-05 ? 
2 'EM metadata'     1 0 2025-03-05 ? 
3 FSC               1 0 2025-03-05 ? 
4 'Half map'        1 0 2025-03-05 1 
5 'Half map'        1 0 2025-03-05 2 
6 Image             1 0 2025-03-05 ? 
7 'Primary map'     1 0 2025-03-05 ? 
8 'Structure model' 1 1 2025-03-19 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8 'Structure model' 'Data collection'     
2 8 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8 'Structure model' citation        
2 8 'Structure model' citation_author 
3 8 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 8 'Structure model' '_citation.country'              
2 8 'Structure model' '_citation.journal_abbrev'       
3 8 'Structure model' '_citation.journal_id_CSD'       
4 8 'Structure model' '_citation.journal_id_ISSN'      
5 8 'Structure model' '_citation.pdbx_database_id_DOI' 
6 8 'Structure model' '_citation.title'                
7 8 'Structure model' '_citation.year'                 
8 8 'Structure model' '_em_admin.last_update'          
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JTC 
_pdbx_database_status.recvd_initial_deposition_date   2024-10-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of bovine UBA7-UBE2L6-ISG15' 
_pdbx_database_related.db_id          EMD-61794 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              kpwu@gate.sinica.edu.tw 
_pdbx_contact_author.name_first         Kuen-Phon 
_pdbx_contact_author.name_last          Wu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1525-6004 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chen, P.-T.' 1 ?                   
'Wu, K.-P.'   2 0000-0002-1525-6004 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Elife 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2050-084X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Elucidating the Mechanism Underlying UBA7-UBE2L6 Disulfide Complex Formation.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.7554/eLife.105638.1 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chen, P.-T.' 1 ?                   
primary 'Yeh, J.-Y.'  2 ?                   
primary 'Weng, J.-H.' 3 ?                   
primary 'Wu, K.-P.'   4 0000-0002-1525-6004 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'UBA7 protein'                             110119.859 1 ?        ? ? ? 
2 polymer     man 'Ubiquitin/ISG15-conjugating enzyme E2 L6' 18597.215  1 2.3.2.23 ? ? ? 
3 polymer     man 'Ubiquitin-like protein ISG15'             17330.094  1 ?        ? ? ? 
4 non-polymer syn 'ADENOSINE MONOPHOSPHATE'                  347.221    1 ?        ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Ubiquitin E1-like enzyme'                                                                    
2 'E2 ubiquitin-conjugating enzyme L6,Ubiquitin carrier protein L6,Ubiquitin-protein ligase L6' 
3 'Interferon-stimulated gene product 17,Ubiquitin cross-reactive protein,BoUCRP'               
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MDTLETSKLLDKELYSRQLYVLGLPAMQRIQGAKVLLSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSE
QDLGRSRAEASQKLLAELNGAVQVSVYTGDITKDLLLDFQVVVLTASRLEEQLRVGTLCHEHGVCFLVADTRGLVGQLFC
DFGENFTVQDPTEAEPLTANIQHISQGSPGILTLREEAGTHHFHTGDWVTFSGIEGMVELNGCDPRPLHVREDGTLEIGD
TTAFSCYLRGGAVTEVKRAKTVSHEPLDTALLQPRVVAQSAQKVRARCLHQSFRALHKFQQLHGRPPKPWDPVDAEMVVD
LAQAMGPLKGTEGEPLEEQLDEALVRTVALSSAGGLSPMAAVLGAVAAQEVLKAISGKFMPLDQWLYFDALDCLPEDGDP
FPNPEDCAPRRCRYDGQTAVFGTNFQEKLSHQHYLLVGAGAVGCELLKSFALMGLGAGDGGGVTVADMDHVELSNLSRQF
LFRSQDIHRKKAEVAAEATRRLNADLQVTPLNLQLDPTTEDIFGDDFFSGVNGVAAALDTFEARDYVAARCTHFLKPLLE
AGTMGTRGSASVFIPHVTENYKAPSDAASEDAPDPVCTVRYIPATTEHTVQWAKGEFDDLFCESAKTINSHPQALSSPED
LVKSQKQPLLQTMRGVLTERPQTWQDCVLWAFGHWQLRFHYGITQLLRTYPPDKVQEDGTPFWSGPKQCPQPLKFDASQD
MHLLYVLAAANLYAQMHGLPGSQDQTALRGLLNLLPLPDPQNLDRIFASELELDSPSGCKQLHEDLKTWSKGPPLKPLTF
EKDNDSNFHVDFVVAAASLRAQNYGIPVASHAETKRIVGRIIPAVVTTTAAVAGLVGLELYKVVGGPRPRHAFRHSYLHL
AENYFSRWVPKAPDIQKFHHLKWTCWDRLEVPAGQPERTLESLLAHIQELQGLRVTMLLHGSALLYSAGWSEEKQTQHLS
RRVTDLVKKVPGQRVLVLELGYEGEEDDTNFPRLHYKL
;
;MDTLETSKLLDKELYSRQLYVLGLPAMQRIQGAKVLLSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSE
QDLGRSRAEASQKLLAELNGAVQVSVYTGDITKDLLLDFQVVVLTASRLEEQLRVGTLCHEHGVCFLVADTRGLVGQLFC
DFGENFTVQDPTEAEPLTANIQHISQGSPGILTLREEAGTHHFHTGDWVTFSGIEGMVELNGCDPRPLHVREDGTLEIGD
TTAFSCYLRGGAVTEVKRAKTVSHEPLDTALLQPRVVAQSAQKVRARCLHQSFRALHKFQQLHGRPPKPWDPVDAEMVVD
LAQAMGPLKGTEGEPLEEQLDEALVRTVALSSAGGLSPMAAVLGAVAAQEVLKAISGKFMPLDQWLYFDALDCLPEDGDP
FPNPEDCAPRRCRYDGQTAVFGTNFQEKLSHQHYLLVGAGAVGCELLKSFALMGLGAGDGGGVTVADMDHVELSNLSRQF
LFRSQDIHRKKAEVAAEATRRLNADLQVTPLNLQLDPTTEDIFGDDFFSGVNGVAAALDTFEARDYVAARCTHFLKPLLE
AGTMGTRGSASVFIPHVTENYKAPSDAASEDAPDPVCTVRYIPATTEHTVQWAKGEFDDLFCESAKTINSHPQALSSPED
LVKSQKQPLLQTMRGVLTERPQTWQDCVLWAFGHWQLRFHYGITQLLRTYPPDKVQEDGTPFWSGPKQCPQPLKFDASQD
MHLLYVLAAANLYAQMHGLPGSQDQTALRGLLNLLPLPDPQNLDRIFASELELDSPSGCKQLHEDLKTWSKGPPLKPLTF
EKDNDSNFHVDFVVAAASLRAQNYGIPVASHAETKRIVGRIIPAVVTTTAAVAGLVGLELYKVVGGPRPRHAFRHSYLHL
AENYFSRWVPKAPDIQKFHHLKWTCWDRLEVPAGQPERTLESLLAHIQELQGLRVTMLLHGSALLYSAGWSEEKQTQHLS
RRVTDLVKKVPGQRVLVLELGYEGEEDDTNFPRLHYKL
;
A ? 
2 'polypeptide(L)' no no 
;MAASKRVAKELEDLQKELPKYLRNLSSEEDNVLVWHALLLPERPPYNLKAFRLSISFPREYPFQPPTVKFTTRIYHPNVD
RDGRVCLPIISKKNWKASTRTSQVLEALNMLVNQPEPGQPVRLELAEQLTQDPELFDQMAQEFTLQFGVDRPSHHHHHH
;
;MAASKRVAKELEDLQKELPKYLRNLSSEEDNVLVWHALLLPERPPYNLKAFRLSISFPREYPFQPPTVKFTTRIYHPNVD
RDGRVCLPIISKKNWKASTRTSQVLEALNMLVNQPEPGQPVRLELAEQLTQDPELFDQMAQEFTLQFGVDRPSHHHHHH
;
B ? 
3 'polypeptide(L)' no no 
;MGGDLTVKMLGGQEILVPLRDSMTVSELKQFIAQKINVPAFQQRLAHLDSREVLQEGVPLVLQGLRAGSTVLLVVQNCIS
ILVRNDKGRSSPYEVQLKQTVAELKQQVCQKERVQADQFWLSFEGRPMDDEHPLEEYGLMKGCTVFMNLRLRGG
;
;MGGDLTVKMLGGQEILVPLRDSMTVSELKQFIAQKINVPAFQQRLAHLDSREVLQEGVPLVLQGLRAGSTVLLVVQNCIS
ILVRNDKGRSSPYEVQLKQTVAELKQQVCQKERVQADQFWLSFEGRPMDDEHPLEEYGLMKGCTVFMNLRLRGG
;
C ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        'ADENOSINE MONOPHOSPHATE' 
_pdbx_entity_nonpoly.comp_id     AMP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   THR n 
1 4   LEU n 
1 5   GLU n 
1 6   THR n 
1 7   SER n 
1 8   LYS n 
1 9   LEU n 
1 10  LEU n 
1 11  ASP n 
1 12  LYS n 
1 13  GLU n 
1 14  LEU n 
1 15  TYR n 
1 16  SER n 
1 17  ARG n 
1 18  GLN n 
1 19  LEU n 
1 20  TYR n 
1 21  VAL n 
1 22  LEU n 
1 23  GLY n 
1 24  LEU n 
1 25  PRO n 
1 26  ALA n 
1 27  MET n 
1 28  GLN n 
1 29  ARG n 
1 30  ILE n 
1 31  GLN n 
1 32  GLY n 
1 33  ALA n 
1 34  LYS n 
1 35  VAL n 
1 36  LEU n 
1 37  LEU n 
1 38  SER n 
1 39  GLY n 
1 40  LEU n 
1 41  GLN n 
1 42  GLY n 
1 43  LEU n 
1 44  GLY n 
1 45  ALA n 
1 46  GLU n 
1 47  VAL n 
1 48  ALA n 
1 49  LYS n 
1 50  ASN n 
1 51  LEU n 
1 52  VAL n 
1 53  LEU n 
1 54  MET n 
1 55  GLY n 
1 56  VAL n 
1 57  GLY n 
1 58  SER n 
1 59  LEU n 
1 60  THR n 
1 61  LEU n 
1 62  HIS n 
1 63  ASP n 
1 64  PRO n 
1 65  HIS n 
1 66  PRO n 
1 67  THR n 
1 68  CYS n 
1 69  TRP n 
1 70  SER n 
1 71  ASP n 
1 72  LEU n 
1 73  ALA n 
1 74  ALA n 
1 75  GLN n 
1 76  PHE n 
1 77  LEU n 
1 78  LEU n 
1 79  SER n 
1 80  GLU n 
1 81  GLN n 
1 82  ASP n 
1 83  LEU n 
1 84  GLY n 
1 85  ARG n 
1 86  SER n 
1 87  ARG n 
1 88  ALA n 
1 89  GLU n 
1 90  ALA n 
1 91  SER n 
1 92  GLN n 
1 93  LYS n 
1 94  LEU n 
1 95  LEU n 
1 96  ALA n 
1 97  GLU n 
1 98  LEU n 
1 99  ASN n 
1 100 GLY n 
1 101 ALA n 
1 102 VAL n 
1 103 GLN n 
1 104 VAL n 
1 105 SER n 
1 106 VAL n 
1 107 TYR n 
1 108 THR n 
1 109 GLY n 
1 110 ASP n 
1 111 ILE n 
1 112 THR n 
1 113 LYS n 
1 114 ASP n 
1 115 LEU n 
1 116 LEU n 
1 117 LEU n 
1 118 ASP n 
1 119 PHE n 
1 120 GLN n 
1 121 VAL n 
1 122 VAL n 
1 123 VAL n 
1 124 LEU n 
1 125 THR n 
1 126 ALA n 
1 127 SER n 
1 128 ARG n 
1 129 LEU n 
1 130 GLU n 
1 131 GLU n 
1 132 GLN n 
1 133 LEU n 
1 134 ARG n 
1 135 VAL n 
1 136 GLY n 
1 137 THR n 
1 138 LEU n 
1 139 CYS n 
1 140 HIS n 
1 141 GLU n 
1 142 HIS n 
1 143 GLY n 
1 144 VAL n 
1 145 CYS n 
1 146 PHE n 
1 147 LEU n 
1 148 VAL n 
1 149 ALA n 
1 150 ASP n 
1 151 THR n 
1 152 ARG n 
1 153 GLY n 
1 154 LEU n 
1 155 VAL n 
1 156 GLY n 
1 157 GLN n 
1 158 LEU n 
1 159 PHE n 
1 160 CYS n 
1 161 ASP n 
1 162 PHE n 
1 163 GLY n 
1 164 GLU n 
1 165 ASN n 
1 166 PHE n 
1 167 THR n 
1 168 VAL n 
1 169 GLN n 
1 170 ASP n 
1 171 PRO n 
1 172 THR n 
1 173 GLU n 
1 174 ALA n 
1 175 GLU n 
1 176 PRO n 
1 177 LEU n 
1 178 THR n 
1 179 ALA n 
1 180 ASN n 
1 181 ILE n 
1 182 GLN n 
1 183 HIS n 
1 184 ILE n 
1 185 SER n 
1 186 GLN n 
1 187 GLY n 
1 188 SER n 
1 189 PRO n 
1 190 GLY n 
1 191 ILE n 
1 192 LEU n 
1 193 THR n 
1 194 LEU n 
1 195 ARG n 
1 196 GLU n 
1 197 GLU n 
1 198 ALA n 
1 199 GLY n 
1 200 THR n 
1 201 HIS n 
1 202 HIS n 
1 203 PHE n 
1 204 HIS n 
1 205 THR n 
1 206 GLY n 
1 207 ASP n 
1 208 TRP n 
1 209 VAL n 
1 210 THR n 
1 211 PHE n 
1 212 SER n 
1 213 GLY n 
1 214 ILE n 
1 215 GLU n 
1 216 GLY n 
1 217 MET n 
1 218 VAL n 
1 219 GLU n 
1 220 LEU n 
1 221 ASN n 
1 222 GLY n 
1 223 CYS n 
1 224 ASP n 
1 225 PRO n 
1 226 ARG n 
1 227 PRO n 
1 228 LEU n 
1 229 HIS n 
1 230 VAL n 
1 231 ARG n 
1 232 GLU n 
1 233 ASP n 
1 234 GLY n 
1 235 THR n 
1 236 LEU n 
1 237 GLU n 
1 238 ILE n 
1 239 GLY n 
1 240 ASP n 
1 241 THR n 
1 242 THR n 
1 243 ALA n 
1 244 PHE n 
1 245 SER n 
1 246 CYS n 
1 247 TYR n 
1 248 LEU n 
1 249 ARG n 
1 250 GLY n 
1 251 GLY n 
1 252 ALA n 
1 253 VAL n 
1 254 THR n 
1 255 GLU n 
1 256 VAL n 
1 257 LYS n 
1 258 ARG n 
1 259 ALA n 
1 260 LYS n 
1 261 THR n 
1 262 VAL n 
1 263 SER n 
1 264 HIS n 
1 265 GLU n 
1 266 PRO n 
1 267 LEU n 
1 268 ASP n 
1 269 THR n 
1 270 ALA n 
1 271 LEU n 
1 272 LEU n 
1 273 GLN n 
1 274 PRO n 
1 275 ARG n 
1 276 VAL n 
1 277 VAL n 
1 278 ALA n 
1 279 GLN n 
1 280 SER n 
1 281 ALA n 
1 282 GLN n 
1 283 LYS n 
1 284 VAL n 
1 285 ARG n 
1 286 ALA n 
1 287 ARG n 
1 288 CYS n 
1 289 LEU n 
1 290 HIS n 
1 291 GLN n 
1 292 SER n 
1 293 PHE n 
1 294 ARG n 
1 295 ALA n 
1 296 LEU n 
1 297 HIS n 
1 298 LYS n 
1 299 PHE n 
1 300 GLN n 
1 301 GLN n 
1 302 LEU n 
1 303 HIS n 
1 304 GLY n 
1 305 ARG n 
1 306 PRO n 
1 307 PRO n 
1 308 LYS n 
1 309 PRO n 
1 310 TRP n 
1 311 ASP n 
1 312 PRO n 
1 313 VAL n 
1 314 ASP n 
1 315 ALA n 
1 316 GLU n 
1 317 MET n 
1 318 VAL n 
1 319 VAL n 
1 320 ASP n 
1 321 LEU n 
1 322 ALA n 
1 323 GLN n 
1 324 ALA n 
1 325 MET n 
1 326 GLY n 
1 327 PRO n 
1 328 LEU n 
1 329 LYS n 
1 330 GLY n 
1 331 THR n 
1 332 GLU n 
1 333 GLY n 
1 334 GLU n 
1 335 PRO n 
1 336 LEU n 
1 337 GLU n 
1 338 GLU n 
1 339 GLN n 
1 340 LEU n 
1 341 ASP n 
1 342 GLU n 
1 343 ALA n 
1 344 LEU n 
1 345 VAL n 
1 346 ARG n 
1 347 THR n 
1 348 VAL n 
1 349 ALA n 
1 350 LEU n 
1 351 SER n 
1 352 SER n 
1 353 ALA n 
1 354 GLY n 
1 355 GLY n 
1 356 LEU n 
1 357 SER n 
1 358 PRO n 
1 359 MET n 
1 360 ALA n 
1 361 ALA n 
1 362 VAL n 
1 363 LEU n 
1 364 GLY n 
1 365 ALA n 
1 366 VAL n 
1 367 ALA n 
1 368 ALA n 
1 369 GLN n 
1 370 GLU n 
1 371 VAL n 
1 372 LEU n 
1 373 LYS n 
1 374 ALA n 
1 375 ILE n 
1 376 SER n 
1 377 GLY n 
1 378 LYS n 
1 379 PHE n 
1 380 MET n 
1 381 PRO n 
1 382 LEU n 
1 383 ASP n 
1 384 GLN n 
1 385 TRP n 
1 386 LEU n 
1 387 TYR n 
1 388 PHE n 
1 389 ASP n 
1 390 ALA n 
1 391 LEU n 
1 392 ASP n 
1 393 CYS n 
1 394 LEU n 
1 395 PRO n 
1 396 GLU n 
1 397 ASP n 
1 398 GLY n 
1 399 ASP n 
1 400 PRO n 
1 401 PHE n 
1 402 PRO n 
1 403 ASN n 
1 404 PRO n 
1 405 GLU n 
1 406 ASP n 
1 407 CYS n 
1 408 ALA n 
1 409 PRO n 
1 410 ARG n 
1 411 ARG n 
1 412 CYS n 
1 413 ARG n 
1 414 TYR n 
1 415 ASP n 
1 416 GLY n 
1 417 GLN n 
1 418 THR n 
1 419 ALA n 
1 420 VAL n 
1 421 PHE n 
1 422 GLY n 
1 423 THR n 
1 424 ASN n 
1 425 PHE n 
1 426 GLN n 
1 427 GLU n 
1 428 LYS n 
1 429 LEU n 
1 430 SER n 
1 431 HIS n 
1 432 GLN n 
1 433 HIS n 
1 434 TYR n 
1 435 LEU n 
1 436 LEU n 
1 437 VAL n 
1 438 GLY n 
1 439 ALA n 
1 440 GLY n 
1 441 ALA n 
1 442 VAL n 
1 443 GLY n 
1 444 CYS n 
1 445 GLU n 
1 446 LEU n 
1 447 LEU n 
1 448 LYS n 
1 449 SER n 
1 450 PHE n 
1 451 ALA n 
1 452 LEU n 
1 453 MET n 
1 454 GLY n 
1 455 LEU n 
1 456 GLY n 
1 457 ALA n 
1 458 GLY n 
1 459 ASP n 
1 460 GLY n 
1 461 GLY n 
1 462 GLY n 
1 463 VAL n 
1 464 THR n 
1 465 VAL n 
1 466 ALA n 
1 467 ASP n 
1 468 MET n 
1 469 ASP n 
1 470 HIS n 
1 471 VAL n 
1 472 GLU n 
1 473 LEU n 
1 474 SER n 
1 475 ASN n 
1 476 LEU n 
1 477 SER n 
1 478 ARG n 
1 479 GLN n 
1 480 PHE n 
1 481 LEU n 
1 482 PHE n 
1 483 ARG n 
1 484 SER n 
1 485 GLN n 
1 486 ASP n 
1 487 ILE n 
1 488 HIS n 
1 489 ARG n 
1 490 LYS n 
1 491 LYS n 
1 492 ALA n 
1 493 GLU n 
1 494 VAL n 
1 495 ALA n 
1 496 ALA n 
1 497 GLU n 
1 498 ALA n 
1 499 THR n 
1 500 ARG n 
1 501 ARG n 
1 502 LEU n 
1 503 ASN n 
1 504 ALA n 
1 505 ASP n 
1 506 LEU n 
1 507 GLN n 
1 508 VAL n 
1 509 THR n 
1 510 PRO n 
1 511 LEU n 
1 512 ASN n 
1 513 LEU n 
1 514 GLN n 
1 515 LEU n 
1 516 ASP n 
1 517 PRO n 
1 518 THR n 
1 519 THR n 
1 520 GLU n 
1 521 ASP n 
1 522 ILE n 
1 523 PHE n 
1 524 GLY n 
1 525 ASP n 
1 526 ASP n 
1 527 PHE n 
1 528 PHE n 
1 529 SER n 
1 530 GLY n 
1 531 VAL n 
1 532 ASN n 
1 533 GLY n 
1 534 VAL n 
1 535 ALA n 
1 536 ALA n 
1 537 ALA n 
1 538 LEU n 
1 539 ASP n 
1 540 THR n 
1 541 PHE n 
1 542 GLU n 
1 543 ALA n 
1 544 ARG n 
1 545 ASP n 
1 546 TYR n 
1 547 VAL n 
1 548 ALA n 
1 549 ALA n 
1 550 ARG n 
1 551 CYS n 
1 552 THR n 
1 553 HIS n 
1 554 PHE n 
1 555 LEU n 
1 556 LYS n 
1 557 PRO n 
1 558 LEU n 
1 559 LEU n 
1 560 GLU n 
1 561 ALA n 
1 562 GLY n 
1 563 THR n 
1 564 MET n 
1 565 GLY n 
1 566 THR n 
1 567 ARG n 
1 568 GLY n 
1 569 SER n 
1 570 ALA n 
1 571 SER n 
1 572 VAL n 
1 573 PHE n 
1 574 ILE n 
1 575 PRO n 
1 576 HIS n 
1 577 VAL n 
1 578 THR n 
1 579 GLU n 
1 580 ASN n 
1 581 TYR n 
1 582 LYS n 
1 583 ALA n 
1 584 PRO n 
1 585 SER n 
1 586 ASP n 
1 587 ALA n 
1 588 ALA n 
1 589 SER n 
1 590 GLU n 
1 591 ASP n 
1 592 ALA n 
1 593 PRO n 
1 594 ASP n 
1 595 PRO n 
1 596 VAL n 
1 597 CYS n 
1 598 THR n 
1 599 VAL n 
1 600 ARG n 
1 601 TYR n 
1 602 ILE n 
1 603 PRO n 
1 604 ALA n 
1 605 THR n 
1 606 THR n 
1 607 GLU n 
1 608 HIS n 
1 609 THR n 
1 610 VAL n 
1 611 GLN n 
1 612 TRP n 
1 613 ALA n 
1 614 LYS n 
1 615 GLY n 
1 616 GLU n 
1 617 PHE n 
1 618 ASP n 
1 619 ASP n 
1 620 LEU n 
1 621 PHE n 
1 622 CYS n 
1 623 GLU n 
1 624 SER n 
1 625 ALA n 
1 626 LYS n 
1 627 THR n 
1 628 ILE n 
1 629 ASN n 
1 630 SER n 
1 631 HIS n 
1 632 PRO n 
1 633 GLN n 
1 634 ALA n 
1 635 LEU n 
1 636 SER n 
1 637 SER n 
1 638 PRO n 
1 639 GLU n 
1 640 ASP n 
1 641 LEU n 
1 642 VAL n 
1 643 LYS n 
1 644 SER n 
1 645 GLN n 
1 646 LYS n 
1 647 GLN n 
1 648 PRO n 
1 649 LEU n 
1 650 LEU n 
1 651 GLN n 
1 652 THR n 
1 653 MET n 
1 654 ARG n 
1 655 GLY n 
1 656 VAL n 
1 657 LEU n 
1 658 THR n 
1 659 GLU n 
1 660 ARG n 
1 661 PRO n 
1 662 GLN n 
1 663 THR n 
1 664 TRP n 
1 665 GLN n 
1 666 ASP n 
1 667 CYS n 
1 668 VAL n 
1 669 LEU n 
1 670 TRP n 
1 671 ALA n 
1 672 PHE n 
1 673 GLY n 
1 674 HIS n 
1 675 TRP n 
1 676 GLN n 
1 677 LEU n 
1 678 ARG n 
1 679 PHE n 
1 680 HIS n 
1 681 TYR n 
1 682 GLY n 
1 683 ILE n 
1 684 THR n 
1 685 GLN n 
1 686 LEU n 
1 687 LEU n 
1 688 ARG n 
1 689 THR n 
1 690 TYR n 
1 691 PRO n 
1 692 PRO n 
1 693 ASP n 
1 694 LYS n 
1 695 VAL n 
1 696 GLN n 
1 697 GLU n 
1 698 ASP n 
1 699 GLY n 
1 700 THR n 
1 701 PRO n 
1 702 PHE n 
1 703 TRP n 
1 704 SER n 
1 705 GLY n 
1 706 PRO n 
1 707 LYS n 
1 708 GLN n 
1 709 CYS n 
1 710 PRO n 
1 711 GLN n 
1 712 PRO n 
1 713 LEU n 
1 714 LYS n 
1 715 PHE n 
1 716 ASP n 
1 717 ALA n 
1 718 SER n 
1 719 GLN n 
1 720 ASP n 
1 721 MET n 
1 722 HIS n 
1 723 LEU n 
1 724 LEU n 
1 725 TYR n 
1 726 VAL n 
1 727 LEU n 
1 728 ALA n 
1 729 ALA n 
1 730 ALA n 
1 731 ASN n 
1 732 LEU n 
1 733 TYR n 
1 734 ALA n 
1 735 GLN n 
1 736 MET n 
1 737 HIS n 
1 738 GLY n 
1 739 LEU n 
1 740 PRO n 
1 741 GLY n 
1 742 SER n 
1 743 GLN n 
1 744 ASP n 
1 745 GLN n 
1 746 THR n 
1 747 ALA n 
1 748 LEU n 
1 749 ARG n 
1 750 GLY n 
1 751 LEU n 
1 752 LEU n 
1 753 ASN n 
1 754 LEU n 
1 755 LEU n 
1 756 PRO n 
1 757 LEU n 
1 758 PRO n 
1 759 ASP n 
1 760 PRO n 
1 761 GLN n 
1 762 ASN n 
1 763 LEU n 
1 764 ASP n 
1 765 ARG n 
1 766 ILE n 
1 767 PHE n 
1 768 ALA n 
1 769 SER n 
1 770 GLU n 
1 771 LEU n 
1 772 GLU n 
1 773 LEU n 
1 774 ASP n 
1 775 SER n 
1 776 PRO n 
1 777 SER n 
1 778 GLY n 
1 779 CYS n 
1 780 LYS n 
1 781 GLN n 
1 782 LEU n 
1 783 HIS n 
1 784 GLU n 
1 785 ASP n 
1 786 LEU n 
1 787 LYS n 
1 788 THR n 
1 789 TRP n 
1 790 SER n 
1 791 LYS n 
1 792 GLY n 
1 793 PRO n 
1 794 PRO n 
1 795 LEU n 
1 796 LYS n 
1 797 PRO n 
1 798 LEU n 
1 799 THR n 
1 800 PHE n 
1 801 GLU n 
1 802 LYS n 
1 803 ASP n 
1 804 ASN n 
1 805 ASP n 
1 806 SER n 
1 807 ASN n 
1 808 PHE n 
1 809 HIS n 
1 810 VAL n 
1 811 ASP n 
1 812 PHE n 
1 813 VAL n 
1 814 VAL n 
1 815 ALA n 
1 816 ALA n 
1 817 ALA n 
1 818 SER n 
1 819 LEU n 
1 820 ARG n 
1 821 ALA n 
1 822 GLN n 
1 823 ASN n 
1 824 TYR n 
1 825 GLY n 
1 826 ILE n 
1 827 PRO n 
1 828 VAL n 
1 829 ALA n 
1 830 SER n 
1 831 HIS n 
1 832 ALA n 
1 833 GLU n 
1 834 THR n 
1 835 LYS n 
1 836 ARG n 
1 837 ILE n 
1 838 VAL n 
1 839 GLY n 
1 840 ARG n 
1 841 ILE n 
1 842 ILE n 
1 843 PRO n 
1 844 ALA n 
1 845 VAL n 
1 846 VAL n 
1 847 THR n 
1 848 THR n 
1 849 THR n 
1 850 ALA n 
1 851 ALA n 
1 852 VAL n 
1 853 ALA n 
1 854 GLY n 
1 855 LEU n 
1 856 VAL n 
1 857 GLY n 
1 858 LEU n 
1 859 GLU n 
1 860 LEU n 
1 861 TYR n 
1 862 LYS n 
1 863 VAL n 
1 864 VAL n 
1 865 GLY n 
1 866 GLY n 
1 867 PRO n 
1 868 ARG n 
1 869 PRO n 
1 870 ARG n 
1 871 HIS n 
1 872 ALA n 
1 873 PHE n 
1 874 ARG n 
1 875 HIS n 
1 876 SER n 
1 877 TYR n 
1 878 LEU n 
1 879 HIS n 
1 880 LEU n 
1 881 ALA n 
1 882 GLU n 
1 883 ASN n 
1 884 TYR n 
1 885 PHE n 
1 886 SER n 
1 887 ARG n 
1 888 TRP n 
1 889 VAL n 
1 890 PRO n 
1 891 LYS n 
1 892 ALA n 
1 893 PRO n 
1 894 ASP n 
1 895 ILE n 
1 896 GLN n 
1 897 LYS n 
1 898 PHE n 
1 899 HIS n 
1 900 HIS n 
1 901 LEU n 
1 902 LYS n 
1 903 TRP n 
1 904 THR n 
1 905 CYS n 
1 906 TRP n 
1 907 ASP n 
1 908 ARG n 
1 909 LEU n 
1 910 GLU n 
1 911 VAL n 
1 912 PRO n 
1 913 ALA n 
1 914 GLY n 
1 915 GLN n 
1 916 PRO n 
1 917 GLU n 
1 918 ARG n 
1 919 THR n 
1 920 LEU n 
1 921 GLU n 
1 922 SER n 
1 923 LEU n 
1 924 LEU n 
1 925 ALA n 
1 926 HIS n 
1 927 ILE n 
1 928 GLN n 
1 929 GLU n 
1 930 LEU n 
1 931 GLN n 
1 932 GLY n 
1 933 LEU n 
1 934 ARG n 
1 935 VAL n 
1 936 THR n 
1 937 MET n 
1 938 LEU n 
1 939 LEU n 
1 940 HIS n 
1 941 GLY n 
1 942 SER n 
1 943 ALA n 
1 944 LEU n 
1 945 LEU n 
1 946 TYR n 
1 947 SER n 
1 948 ALA n 
1 949 GLY n 
1 950 TRP n 
1 951 SER n 
1 952 GLU n 
1 953 GLU n 
1 954 LYS n 
1 955 GLN n 
1 956 THR n 
1 957 GLN n 
1 958 HIS n 
1 959 LEU n 
1 960 SER n 
1 961 ARG n 
1 962 ARG n 
1 963 VAL n 
1 964 THR n 
1 965 ASP n 
1 966 LEU n 
1 967 VAL n 
1 968 LYS n 
1 969 LYS n 
1 970 VAL n 
1 971 PRO n 
1 972 GLY n 
1 973 GLN n 
1 974 ARG n 
1 975 VAL n 
1 976 LEU n 
1 977 VAL n 
1 978 LEU n 
1 979 GLU n 
1 980 LEU n 
1 981 GLY n 
1 982 TYR n 
1 983 GLU n 
1 984 GLY n 
1 985 GLU n 
1 986 GLU n 
1 987 ASP n 
1 988 ASP n 
1 989 THR n 
1 990 ASN n 
1 991 PHE n 
1 992 PRO n 
1 993 ARG n 
1 994 LEU n 
1 995 HIS n 
1 996 TYR n 
1 997 LYS n 
1 998 LEU n 
2 1   MET n 
2 2   ALA n 
2 3   ALA n 
2 4   SER n 
2 5   LYS n 
2 6   ARG n 
2 7   VAL n 
2 8   ALA n 
2 9   LYS n 
2 10  GLU n 
2 11  LEU n 
2 12  GLU n 
2 13  ASP n 
2 14  LEU n 
2 15  GLN n 
2 16  LYS n 
2 17  GLU n 
2 18  LEU n 
2 19  PRO n 
2 20  LYS n 
2 21  TYR n 
2 22  LEU n 
2 23  ARG n 
2 24  ASN n 
2 25  LEU n 
2 26  SER n 
2 27  SER n 
2 28  GLU n 
2 29  GLU n 
2 30  ASP n 
2 31  ASN n 
2 32  VAL n 
2 33  LEU n 
2 34  VAL n 
2 35  TRP n 
2 36  HIS n 
2 37  ALA n 
2 38  LEU n 
2 39  LEU n 
2 40  LEU n 
2 41  PRO n 
2 42  GLU n 
2 43  ARG n 
2 44  PRO n 
2 45  PRO n 
2 46  TYR n 
2 47  ASN n 
2 48  LEU n 
2 49  LYS n 
2 50  ALA n 
2 51  PHE n 
2 52  ARG n 
2 53  LEU n 
2 54  SER n 
2 55  ILE n 
2 56  SER n 
2 57  PHE n 
2 58  PRO n 
2 59  ARG n 
2 60  GLU n 
2 61  TYR n 
2 62  PRO n 
2 63  PHE n 
2 64  GLN n 
2 65  PRO n 
2 66  PRO n 
2 67  THR n 
2 68  VAL n 
2 69  LYS n 
2 70  PHE n 
2 71  THR n 
2 72  THR n 
2 73  ARG n 
2 74  ILE n 
2 75  TYR n 
2 76  HIS n 
2 77  PRO n 
2 78  ASN n 
2 79  VAL n 
2 80  ASP n 
2 81  ARG n 
2 82  ASP n 
2 83  GLY n 
2 84  ARG n 
2 85  VAL n 
2 86  CYS n 
2 87  LEU n 
2 88  PRO n 
2 89  ILE n 
2 90  ILE n 
2 91  SER n 
2 92  LYS n 
2 93  LYS n 
2 94  ASN n 
2 95  TRP n 
2 96  LYS n 
2 97  ALA n 
2 98  SER n 
2 99  THR n 
2 100 ARG n 
2 101 THR n 
2 102 SER n 
2 103 GLN n 
2 104 VAL n 
2 105 LEU n 
2 106 GLU n 
2 107 ALA n 
2 108 LEU n 
2 109 ASN n 
2 110 MET n 
2 111 LEU n 
2 112 VAL n 
2 113 ASN n 
2 114 GLN n 
2 115 PRO n 
2 116 GLU n 
2 117 PRO n 
2 118 GLY n 
2 119 GLN n 
2 120 PRO n 
2 121 VAL n 
2 122 ARG n 
2 123 LEU n 
2 124 GLU n 
2 125 LEU n 
2 126 ALA n 
2 127 GLU n 
2 128 GLN n 
2 129 LEU n 
2 130 THR n 
2 131 GLN n 
2 132 ASP n 
2 133 PRO n 
2 134 GLU n 
2 135 LEU n 
2 136 PHE n 
2 137 ASP n 
2 138 GLN n 
2 139 MET n 
2 140 ALA n 
2 141 GLN n 
2 142 GLU n 
2 143 PHE n 
2 144 THR n 
2 145 LEU n 
2 146 GLN n 
2 147 PHE n 
2 148 GLY n 
2 149 VAL n 
2 150 ASP n 
2 151 ARG n 
2 152 PRO n 
2 153 SER n 
2 154 HIS n 
2 155 HIS n 
2 156 HIS n 
2 157 HIS n 
2 158 HIS n 
2 159 HIS n 
3 1   MET n 
3 2   GLY n 
3 3   GLY n 
3 4   ASP n 
3 5   LEU n 
3 6   THR n 
3 7   VAL n 
3 8   LYS n 
3 9   MET n 
3 10  LEU n 
3 11  GLY n 
3 12  GLY n 
3 13  GLN n 
3 14  GLU n 
3 15  ILE n 
3 16  LEU n 
3 17  VAL n 
3 18  PRO n 
3 19  LEU n 
3 20  ARG n 
3 21  ASP n 
3 22  SER n 
3 23  MET n 
3 24  THR n 
3 25  VAL n 
3 26  SER n 
3 27  GLU n 
3 28  LEU n 
3 29  LYS n 
3 30  GLN n 
3 31  PHE n 
3 32  ILE n 
3 33  ALA n 
3 34  GLN n 
3 35  LYS n 
3 36  ILE n 
3 37  ASN n 
3 38  VAL n 
3 39  PRO n 
3 40  ALA n 
3 41  PHE n 
3 42  GLN n 
3 43  GLN n 
3 44  ARG n 
3 45  LEU n 
3 46  ALA n 
3 47  HIS n 
3 48  LEU n 
3 49  ASP n 
3 50  SER n 
3 51  ARG n 
3 52  GLU n 
3 53  VAL n 
3 54  LEU n 
3 55  GLN n 
3 56  GLU n 
3 57  GLY n 
3 58  VAL n 
3 59  PRO n 
3 60  LEU n 
3 61  VAL n 
3 62  LEU n 
3 63  GLN n 
3 64  GLY n 
3 65  LEU n 
3 66  ARG n 
3 67  ALA n 
3 68  GLY n 
3 69  SER n 
3 70  THR n 
3 71  VAL n 
3 72  LEU n 
3 73  LEU n 
3 74  VAL n 
3 75  VAL n 
3 76  GLN n 
3 77  ASN n 
3 78  CYS n 
3 79  ILE n 
3 80  SER n 
3 81  ILE n 
3 82  LEU n 
3 83  VAL n 
3 84  ARG n 
3 85  ASN n 
3 86  ASP n 
3 87  LYS n 
3 88  GLY n 
3 89  ARG n 
3 90  SER n 
3 91  SER n 
3 92  PRO n 
3 93  TYR n 
3 94  GLU n 
3 95  VAL n 
3 96  GLN n 
3 97  LEU n 
3 98  LYS n 
3 99  GLN n 
3 100 THR n 
3 101 VAL n 
3 102 ALA n 
3 103 GLU n 
3 104 LEU n 
3 105 LYS n 
3 106 GLN n 
3 107 GLN n 
3 108 VAL n 
3 109 CYS n 
3 110 GLN n 
3 111 LYS n 
3 112 GLU n 
3 113 ARG n 
3 114 VAL n 
3 115 GLN n 
3 116 ALA n 
3 117 ASP n 
3 118 GLN n 
3 119 PHE n 
3 120 TRP n 
3 121 LEU n 
3 122 SER n 
3 123 PHE n 
3 124 GLU n 
3 125 GLY n 
3 126 ARG n 
3 127 PRO n 
3 128 MET n 
3 129 ASP n 
3 130 ASP n 
3 131 GLU n 
3 132 HIS n 
3 133 PRO n 
3 134 LEU n 
3 135 GLU n 
3 136 GLU n 
3 137 TYR n 
3 138 GLY n 
3 139 LEU n 
3 140 MET n 
3 141 LYS n 
3 142 GLY n 
3 143 CYS n 
3 144 THR n 
3 145 VAL n 
3 146 PHE n 
3 147 MET n 
3 148 ASN n 
3 149 LEU n 
3 150 ARG n 
3 151 LEU n 
3 152 ARG n 
3 153 GLY n 
3 154 GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 998 'domestic cattle' ? UBA7                       ? ? ? ? ? ? 'Bos taurus' 9913 ? ? ? ? ? ? ? 
? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 159 'domestic cattle' ? UBE2L6                     ? ? ? ? ? ? 'Bos taurus' 9913 ? ? ? ? ? ? ? 
? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 154 'domestic cattle' ? 'ISG15, G1P2, ISG17, UCRP' ? ? ? ? ? ? 'Bos taurus' 9913 ? ? ? ? ? ? ? 
? 'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                   ? 'C3 H7 N O2'      89.093  
AMP non-polymer         . 'ADENOSINE MONOPHOSPHATE' ? 'C10 H14 N5 O7 P' 347.221 
ARG 'L-peptide linking' y ARGININE                  ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'           ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                  ? 'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE                 ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'           ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                   ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                 ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                   ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                    ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE             ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                   ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                    ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                 ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                  ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                    ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ASP 2   2   ?   ?   ?   A . n 
A 1 3   THR 3   3   ?   ?   ?   A . n 
A 1 4   LEU 4   4   ?   ?   ?   A . n 
A 1 5   GLU 5   5   ?   ?   ?   A . n 
A 1 6   THR 6   6   ?   ?   ?   A . n 
A 1 7   SER 7   7   ?   ?   ?   A . n 
A 1 8   LYS 8   8   ?   ?   ?   A . n 
A 1 9   LEU 9   9   ?   ?   ?   A . n 
A 1 10  LEU 10  10  ?   ?   ?   A . n 
A 1 11  ASP 11  11  ?   ?   ?   A . n 
A 1 12  LYS 12  12  ?   ?   ?   A . n 
A 1 13  GLU 13  13  ?   ?   ?   A . n 
A 1 14  LEU 14  14  ?   ?   ?   A . n 
A 1 15  TYR 15  15  ?   ?   ?   A . n 
A 1 16  SER 16  16  ?   ?   ?   A . n 
A 1 17  ARG 17  17  ?   ?   ?   A . n 
A 1 18  GLN 18  18  ?   ?   ?   A . n 
A 1 19  LEU 19  19  ?   ?   ?   A . n 
A 1 20  TYR 20  20  ?   ?   ?   A . n 
A 1 21  VAL 21  21  ?   ?   ?   A . n 
A 1 22  LEU 22  22  ?   ?   ?   A . n 
A 1 23  GLY 23  23  ?   ?   ?   A . n 
A 1 24  LEU 24  24  ?   ?   ?   A . n 
A 1 25  PRO 25  25  ?   ?   ?   A . n 
A 1 26  ALA 26  26  ?   ?   ?   A . n 
A 1 27  MET 27  27  ?   ?   ?   A . n 
A 1 28  GLN 28  28  ?   ?   ?   A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  ILE 30  30  30  ILE ILE A . n 
A 1 31  GLN 31  31  31  GLN GLN A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  LYS 34  34  34  LYS LYS A . n 
A 1 35  VAL 35  35  35  VAL VAL A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  SER 38  38  38  SER SER A . n 
A 1 39  GLY 39  39  39  GLY GLY A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  GLN 41  41  41  GLN GLN A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  ALA 45  45  45  ALA ALA A . n 
A 1 46  GLU 46  46  46  GLU GLU A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  LYS 49  49  49  LYS LYS A . n 
A 1 50  ASN 50  50  50  ASN ASN A . n 
A 1 51  LEU 51  51  51  LEU LEU A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  MET 54  54  54  MET MET A . n 
A 1 55  GLY 55  55  55  GLY GLY A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  GLY 57  57  57  GLY GLY A . n 
A 1 58  SER 58  58  58  SER SER A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  THR 60  60  60  THR THR A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  HIS 62  62  62  HIS HIS A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  PRO 64  64  64  PRO PRO A . n 
A 1 65  HIS 65  65  65  HIS HIS A . n 
A 1 66  PRO 66  66  66  PRO PRO A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  CYS 68  68  68  CYS CYS A . n 
A 1 69  TRP 69  69  69  TRP TRP A . n 
A 1 70  SER 70  70  70  SER SER A . n 
A 1 71  ASP 71  71  71  ASP ASP A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  ALA 73  73  73  ALA ALA A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  GLN 75  75  75  GLN GLN A . n 
A 1 76  PHE 76  76  76  PHE PHE A . n 
A 1 77  LEU 77  77  77  LEU LEU A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  GLU 80  80  80  GLU GLU A . n 
A 1 81  GLN 81  81  81  GLN GLN A . n 
A 1 82  ASP 82  82  82  ASP ASP A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  ARG 85  85  85  ARG ARG A . n 
A 1 86  SER 86  86  86  SER SER A . n 
A 1 87  ARG 87  87  87  ARG ARG A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  GLU 89  89  89  GLU GLU A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  SER 91  91  91  SER SER A . n 
A 1 92  GLN 92  92  92  GLN GLN A . n 
A 1 93  LYS 93  93  93  LYS LYS A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  ASN 99  99  99  ASN ASN A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 ALA 101 101 101 ALA ALA A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 GLN 103 103 103 GLN GLN A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 SER 105 105 105 SER SER A . n 
A 1 106 VAL 106 106 106 VAL VAL A . n 
A 1 107 TYR 107 107 107 TYR TYR A . n 
A 1 108 THR 108 108 108 THR THR A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ASP 110 110 110 ASP ASP A . n 
A 1 111 ILE 111 111 111 ILE ILE A . n 
A 1 112 THR 112 112 112 THR THR A . n 
A 1 113 LYS 113 113 113 LYS LYS A . n 
A 1 114 ASP 114 114 114 ASP ASP A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 LEU 117 117 117 LEU LEU A . n 
A 1 118 ASP 118 118 118 ASP ASP A . n 
A 1 119 PHE 119 119 119 PHE PHE A . n 
A 1 120 GLN 120 120 120 GLN GLN A . n 
A 1 121 VAL 121 121 121 VAL VAL A . n 
A 1 122 VAL 122 122 122 VAL VAL A . n 
A 1 123 VAL 123 123 123 VAL VAL A . n 
A 1 124 LEU 124 124 124 LEU LEU A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 SER 127 127 127 SER SER A . n 
A 1 128 ARG 128 128 128 ARG ARG A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 GLU 130 130 130 GLU GLU A . n 
A 1 131 GLU 131 131 131 GLU GLU A . n 
A 1 132 GLN 132 132 132 GLN GLN A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 ARG 134 134 134 ARG ARG A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 THR 137 137 137 THR THR A . n 
A 1 138 LEU 138 138 138 LEU LEU A . n 
A 1 139 CYS 139 139 139 CYS CYS A . n 
A 1 140 HIS 140 140 140 HIS HIS A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 HIS 142 142 142 HIS HIS A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 VAL 144 144 144 VAL VAL A . n 
A 1 145 CYS 145 145 145 CYS CYS A . n 
A 1 146 PHE 146 146 146 PHE PHE A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 THR 151 151 151 THR THR A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 GLY 153 153 153 GLY GLY A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 VAL 155 155 155 VAL VAL A . n 
A 1 156 GLY 156 156 156 GLY GLY A . n 
A 1 157 GLN 157 157 157 GLN GLN A . n 
A 1 158 LEU 158 158 158 LEU LEU A . n 
A 1 159 PHE 159 159 159 PHE PHE A . n 
A 1 160 CYS 160 160 160 CYS CYS A . n 
A 1 161 ASP 161 161 161 ASP ASP A . n 
A 1 162 PHE 162 162 162 PHE PHE A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 GLU 164 164 164 GLU GLU A . n 
A 1 165 ASN 165 165 165 ASN ASN A . n 
A 1 166 PHE 166 166 166 PHE PHE A . n 
A 1 167 THR 167 167 167 THR THR A . n 
A 1 168 VAL 168 168 168 VAL VAL A . n 
A 1 169 GLN 169 169 169 GLN GLN A . n 
A 1 170 ASP 170 170 170 ASP ASP A . n 
A 1 171 PRO 171 171 171 PRO PRO A . n 
A 1 172 THR 172 172 172 THR THR A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 GLU 175 175 175 GLU GLU A . n 
A 1 176 PRO 176 176 176 PRO PRO A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 THR 178 178 178 THR THR A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 ASN 180 180 180 ASN ASN A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 GLN 182 182 182 GLN GLN A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 ILE 184 184 184 ILE ILE A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 GLN 186 186 186 GLN GLN A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 PRO 189 189 189 PRO PRO A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ILE 191 191 191 ILE ILE A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 THR 193 193 193 THR THR A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 ARG 195 195 195 ARG ARG A . n 
A 1 196 GLU 196 196 ?   ?   ?   A . n 
A 1 197 GLU 197 197 ?   ?   ?   A . n 
A 1 198 ALA 198 198 ?   ?   ?   A . n 
A 1 199 GLY 199 199 ?   ?   ?   A . n 
A 1 200 THR 200 200 ?   ?   ?   A . n 
A 1 201 HIS 201 201 201 HIS HIS A . n 
A 1 202 HIS 202 202 202 HIS HIS A . n 
A 1 203 PHE 203 203 203 PHE PHE A . n 
A 1 204 HIS 204 204 204 HIS HIS A . n 
A 1 205 THR 205 205 205 THR THR A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 ASP 207 207 207 ASP ASP A . n 
A 1 208 TRP 208 208 208 TRP TRP A . n 
A 1 209 VAL 209 209 209 VAL VAL A . n 
A 1 210 THR 210 210 210 THR THR A . n 
A 1 211 PHE 211 211 211 PHE PHE A . n 
A 1 212 SER 212 212 212 SER SER A . n 
A 1 213 GLY 213 213 213 GLY GLY A . n 
A 1 214 ILE 214 214 214 ILE ILE A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 GLY 216 216 216 GLY GLY A . n 
A 1 217 MET 217 217 217 MET MET A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 GLU 219 219 219 GLU GLU A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ASN 221 221 221 ASN ASN A . n 
A 1 222 GLY 222 222 222 GLY GLY A . n 
A 1 223 CYS 223 223 223 CYS CYS A . n 
A 1 224 ASP 224 224 224 ASP ASP A . n 
A 1 225 PRO 225 225 225 PRO PRO A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 PRO 227 227 227 PRO PRO A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 HIS 229 229 229 HIS HIS A . n 
A 1 230 VAL 230 230 230 VAL VAL A . n 
A 1 231 ARG 231 231 231 ARG ARG A . n 
A 1 232 GLU 232 232 232 GLU GLU A . n 
A 1 233 ASP 233 233 233 ASP ASP A . n 
A 1 234 GLY 234 234 234 GLY GLY A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 GLU 237 237 237 GLU GLU A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 GLY 239 239 239 GLY GLY A . n 
A 1 240 ASP 240 240 240 ASP ASP A . n 
A 1 241 THR 241 241 241 THR THR A . n 
A 1 242 THR 242 242 242 THR THR A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 SER 245 245 245 SER SER A . n 
A 1 246 CYS 246 246 246 CYS CYS A . n 
A 1 247 TYR 247 247 247 TYR TYR A . n 
A 1 248 LEU 248 248 248 LEU LEU A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 VAL 253 253 253 VAL VAL A . n 
A 1 254 THR 254 254 254 THR THR A . n 
A 1 255 GLU 255 255 255 GLU GLU A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 LYS 257 257 257 LYS LYS A . n 
A 1 258 ARG 258 258 258 ARG ARG A . n 
A 1 259 ALA 259 259 259 ALA ALA A . n 
A 1 260 LYS 260 260 260 LYS LYS A . n 
A 1 261 THR 261 261 261 THR THR A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 HIS 264 264 264 HIS HIS A . n 
A 1 265 GLU 265 265 265 GLU GLU A . n 
A 1 266 PRO 266 266 266 PRO PRO A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 ASP 268 268 268 ASP ASP A . n 
A 1 269 THR 269 269 269 THR THR A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 GLN 273 273 273 GLN GLN A . n 
A 1 274 PRO 274 274 274 PRO PRO A . n 
A 1 275 ARG 275 275 275 ARG ARG A . n 
A 1 276 VAL 276 276 276 VAL VAL A . n 
A 1 277 VAL 277 277 277 VAL VAL A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 GLN 279 279 279 GLN GLN A . n 
A 1 280 SER 280 280 280 SER SER A . n 
A 1 281 ALA 281 281 281 ALA ALA A . n 
A 1 282 GLN 282 282 282 GLN GLN A . n 
A 1 283 LYS 283 283 283 LYS LYS A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 ARG 285 285 285 ARG ARG A . n 
A 1 286 ALA 286 286 286 ALA ALA A . n 
A 1 287 ARG 287 287 287 ARG ARG A . n 
A 1 288 CYS 288 288 288 CYS CYS A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 HIS 290 290 290 HIS HIS A . n 
A 1 291 GLN 291 291 291 GLN GLN A . n 
A 1 292 SER 292 292 292 SER SER A . n 
A 1 293 PHE 293 293 293 PHE PHE A . n 
A 1 294 ARG 294 294 294 ARG ARG A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 HIS 297 297 297 HIS HIS A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 PHE 299 299 299 PHE PHE A . n 
A 1 300 GLN 300 300 300 GLN GLN A . n 
A 1 301 GLN 301 301 301 GLN GLN A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 HIS 303 303 303 HIS HIS A . n 
A 1 304 GLY 304 304 304 GLY GLY A . n 
A 1 305 ARG 305 305 305 ARG ARG A . n 
A 1 306 PRO 306 306 306 PRO PRO A . n 
A 1 307 PRO 307 307 307 PRO PRO A . n 
A 1 308 LYS 308 308 308 LYS LYS A . n 
A 1 309 PRO 309 309 309 PRO PRO A . n 
A 1 310 TRP 310 310 310 TRP TRP A . n 
A 1 311 ASP 311 311 311 ASP ASP A . n 
A 1 312 PRO 312 312 312 PRO PRO A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 ASP 314 314 314 ASP ASP A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 GLU 316 316 316 GLU GLU A . n 
A 1 317 MET 317 317 317 MET MET A . n 
A 1 318 VAL 318 318 318 VAL VAL A . n 
A 1 319 VAL 319 319 319 VAL VAL A . n 
A 1 320 ASP 320 320 320 ASP ASP A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 ALA 322 322 322 ALA ALA A . n 
A 1 323 GLN 323 323 323 GLN GLN A . n 
A 1 324 ALA 324 324 324 ALA ALA A . n 
A 1 325 MET 325 325 325 MET MET A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 PRO 327 327 327 PRO PRO A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 LYS 329 329 329 LYS LYS A . n 
A 1 330 GLY 330 330 ?   ?   ?   A . n 
A 1 331 THR 331 331 ?   ?   ?   A . n 
A 1 332 GLU 332 332 ?   ?   ?   A . n 
A 1 333 GLY 333 333 ?   ?   ?   A . n 
A 1 334 GLU 334 334 ?   ?   ?   A . n 
A 1 335 PRO 335 335 ?   ?   ?   A . n 
A 1 336 LEU 336 336 ?   ?   ?   A . n 
A 1 337 GLU 337 337 ?   ?   ?   A . n 
A 1 338 GLU 338 338 338 GLU GLU A . n 
A 1 339 GLN 339 339 339 GLN GLN A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 ASP 341 341 341 ASP ASP A . n 
A 1 342 GLU 342 342 342 GLU GLU A . n 
A 1 343 ALA 343 343 343 ALA ALA A . n 
A 1 344 LEU 344 344 344 LEU LEU A . n 
A 1 345 VAL 345 345 345 VAL VAL A . n 
A 1 346 ARG 346 346 346 ARG ARG A . n 
A 1 347 THR 347 347 347 THR THR A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 ALA 349 349 349 ALA ALA A . n 
A 1 350 LEU 350 350 350 LEU LEU A . n 
A 1 351 SER 351 351 351 SER SER A . n 
A 1 352 SER 352 352 352 SER SER A . n 
A 1 353 ALA 353 353 353 ALA ALA A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 GLY 355 355 355 GLY GLY A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 SER 357 357 357 SER SER A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 MET 359 359 359 MET MET A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 ALA 361 361 361 ALA ALA A . n 
A 1 362 VAL 362 362 362 VAL VAL A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 ALA 365 365 365 ALA ALA A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 GLN 369 369 369 GLN GLN A . n 
A 1 370 GLU 370 370 370 GLU GLU A . n 
A 1 371 VAL 371 371 371 VAL VAL A . n 
A 1 372 LEU 372 372 372 LEU LEU A . n 
A 1 373 LYS 373 373 373 LYS LYS A . n 
A 1 374 ALA 374 374 374 ALA ALA A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 SER 376 376 376 SER SER A . n 
A 1 377 GLY 377 377 377 GLY GLY A . n 
A 1 378 LYS 378 378 378 LYS LYS A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 MET 380 380 380 MET MET A . n 
A 1 381 PRO 381 381 381 PRO PRO A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 ASP 383 383 383 ASP ASP A . n 
A 1 384 GLN 384 384 384 GLN GLN A . n 
A 1 385 TRP 385 385 385 TRP TRP A . n 
A 1 386 LEU 386 386 386 LEU LEU A . n 
A 1 387 TYR 387 387 387 TYR TYR A . n 
A 1 388 PHE 388 388 388 PHE PHE A . n 
A 1 389 ASP 389 389 389 ASP ASP A . n 
A 1 390 ALA 390 390 390 ALA ALA A . n 
A 1 391 LEU 391 391 391 LEU LEU A . n 
A 1 392 ASP 392 392 392 ASP ASP A . n 
A 1 393 CYS 393 393 393 CYS CYS A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 PRO 395 395 395 PRO PRO A . n 
A 1 396 GLU 396 396 396 GLU GLU A . n 
A 1 397 ASP 397 397 397 ASP ASP A . n 
A 1 398 GLY 398 398 398 GLY GLY A . n 
A 1 399 ASP 399 399 399 ASP ASP A . n 
A 1 400 PRO 400 400 400 PRO PRO A . n 
A 1 401 PHE 401 401 401 PHE PHE A . n 
A 1 402 PRO 402 402 402 PRO PRO A . n 
A 1 403 ASN 403 403 403 ASN ASN A . n 
A 1 404 PRO 404 404 404 PRO PRO A . n 
A 1 405 GLU 405 405 405 GLU GLU A . n 
A 1 406 ASP 406 406 406 ASP ASP A . n 
A 1 407 CYS 407 407 407 CYS CYS A . n 
A 1 408 ALA 408 408 408 ALA ALA A . n 
A 1 409 PRO 409 409 409 PRO PRO A . n 
A 1 410 ARG 410 410 410 ARG ARG A . n 
A 1 411 ARG 411 411 411 ARG ARG A . n 
A 1 412 CYS 412 412 412 CYS CYS A . n 
A 1 413 ARG 413 413 413 ARG ARG A . n 
A 1 414 TYR 414 414 414 TYR TYR A . n 
A 1 415 ASP 415 415 415 ASP ASP A . n 
A 1 416 GLY 416 416 416 GLY GLY A . n 
A 1 417 GLN 417 417 417 GLN GLN A . n 
A 1 418 THR 418 418 418 THR THR A . n 
A 1 419 ALA 419 419 419 ALA ALA A . n 
A 1 420 VAL 420 420 420 VAL VAL A . n 
A 1 421 PHE 421 421 421 PHE PHE A . n 
A 1 422 GLY 422 422 422 GLY GLY A . n 
A 1 423 THR 423 423 423 THR THR A . n 
A 1 424 ASN 424 424 424 ASN ASN A . n 
A 1 425 PHE 425 425 425 PHE PHE A . n 
A 1 426 GLN 426 426 426 GLN GLN A . n 
A 1 427 GLU 427 427 427 GLU GLU A . n 
A 1 428 LYS 428 428 428 LYS LYS A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 SER 430 430 430 SER SER A . n 
A 1 431 HIS 431 431 431 HIS HIS A . n 
A 1 432 GLN 432 432 432 GLN GLN A . n 
A 1 433 HIS 433 433 433 HIS HIS A . n 
A 1 434 TYR 434 434 434 TYR TYR A . n 
A 1 435 LEU 435 435 435 LEU LEU A . n 
A 1 436 LEU 436 436 436 LEU LEU A . n 
A 1 437 VAL 437 437 437 VAL VAL A . n 
A 1 438 GLY 438 438 438 GLY GLY A . n 
A 1 439 ALA 439 439 439 ALA ALA A . n 
A 1 440 GLY 440 440 440 GLY GLY A . n 
A 1 441 ALA 441 441 441 ALA ALA A . n 
A 1 442 VAL 442 442 442 VAL VAL A . n 
A 1 443 GLY 443 443 443 GLY GLY A . n 
A 1 444 CYS 444 444 444 CYS CYS A . n 
A 1 445 GLU 445 445 445 GLU GLU A . n 
A 1 446 LEU 446 446 446 LEU LEU A . n 
A 1 447 LEU 447 447 447 LEU LEU A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 SER 449 449 449 SER SER A . n 
A 1 450 PHE 450 450 450 PHE PHE A . n 
A 1 451 ALA 451 451 451 ALA ALA A . n 
A 1 452 LEU 452 452 452 LEU LEU A . n 
A 1 453 MET 453 453 453 MET MET A . n 
A 1 454 GLY 454 454 454 GLY GLY A . n 
A 1 455 LEU 455 455 455 LEU LEU A . n 
A 1 456 GLY 456 456 456 GLY GLY A . n 
A 1 457 ALA 457 457 457 ALA ALA A . n 
A 1 458 GLY 458 458 458 GLY GLY A . n 
A 1 459 ASP 459 459 459 ASP ASP A . n 
A 1 460 GLY 460 460 460 GLY GLY A . n 
A 1 461 GLY 461 461 461 GLY GLY A . n 
A 1 462 GLY 462 462 462 GLY GLY A . n 
A 1 463 VAL 463 463 463 VAL VAL A . n 
A 1 464 THR 464 464 464 THR THR A . n 
A 1 465 VAL 465 465 465 VAL VAL A . n 
A 1 466 ALA 466 466 466 ALA ALA A . n 
A 1 467 ASP 467 467 467 ASP ASP A . n 
A 1 468 MET 468 468 468 MET MET A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 HIS 470 470 470 HIS HIS A . n 
A 1 471 VAL 471 471 471 VAL VAL A . n 
A 1 472 GLU 472 472 472 GLU GLU A . n 
A 1 473 LEU 473 473 473 LEU LEU A . n 
A 1 474 SER 474 474 474 SER SER A . n 
A 1 475 ASN 475 475 475 ASN ASN A . n 
A 1 476 LEU 476 476 476 LEU LEU A . n 
A 1 477 SER 477 477 477 SER SER A . n 
A 1 478 ARG 478 478 478 ARG ARG A . n 
A 1 479 GLN 479 479 479 GLN GLN A . n 
A 1 480 PHE 480 480 480 PHE PHE A . n 
A 1 481 LEU 481 481 481 LEU LEU A . n 
A 1 482 PHE 482 482 482 PHE PHE A . n 
A 1 483 ARG 483 483 483 ARG ARG A . n 
A 1 484 SER 484 484 484 SER SER A . n 
A 1 485 GLN 485 485 485 GLN GLN A . n 
A 1 486 ASP 486 486 486 ASP ASP A . n 
A 1 487 ILE 487 487 487 ILE ILE A . n 
A 1 488 HIS 488 488 488 HIS HIS A . n 
A 1 489 ARG 489 489 489 ARG ARG A . n 
A 1 490 LYS 490 490 490 LYS LYS A . n 
A 1 491 LYS 491 491 491 LYS LYS A . n 
A 1 492 ALA 492 492 492 ALA ALA A . n 
A 1 493 GLU 493 493 493 GLU GLU A . n 
A 1 494 VAL 494 494 494 VAL VAL A . n 
A 1 495 ALA 495 495 495 ALA ALA A . n 
A 1 496 ALA 496 496 496 ALA ALA A . n 
A 1 497 GLU 497 497 497 GLU GLU A . n 
A 1 498 ALA 498 498 498 ALA ALA A . n 
A 1 499 THR 499 499 499 THR THR A . n 
A 1 500 ARG 500 500 500 ARG ARG A . n 
A 1 501 ARG 501 501 501 ARG ARG A . n 
A 1 502 LEU 502 502 502 LEU LEU A . n 
A 1 503 ASN 503 503 503 ASN ASN A . n 
A 1 504 ALA 504 504 504 ALA ALA A . n 
A 1 505 ASP 505 505 505 ASP ASP A . n 
A 1 506 LEU 506 506 506 LEU LEU A . n 
A 1 507 GLN 507 507 507 GLN GLN A . n 
A 1 508 VAL 508 508 508 VAL VAL A . n 
A 1 509 THR 509 509 509 THR THR A . n 
A 1 510 PRO 510 510 510 PRO PRO A . n 
A 1 511 LEU 511 511 511 LEU LEU A . n 
A 1 512 ASN 512 512 512 ASN ASN A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 GLN 514 514 514 GLN GLN A . n 
A 1 515 LEU 515 515 515 LEU LEU A . n 
A 1 516 ASP 516 516 516 ASP ASP A . n 
A 1 517 PRO 517 517 517 PRO PRO A . n 
A 1 518 THR 518 518 518 THR THR A . n 
A 1 519 THR 519 519 519 THR THR A . n 
A 1 520 GLU 520 520 520 GLU GLU A . n 
A 1 521 ASP 521 521 521 ASP ASP A . n 
A 1 522 ILE 522 522 522 ILE ILE A . n 
A 1 523 PHE 523 523 523 PHE PHE A . n 
A 1 524 GLY 524 524 524 GLY GLY A . n 
A 1 525 ASP 525 525 525 ASP ASP A . n 
A 1 526 ASP 526 526 526 ASP ASP A . n 
A 1 527 PHE 527 527 527 PHE PHE A . n 
A 1 528 PHE 528 528 528 PHE PHE A . n 
A 1 529 SER 529 529 529 SER SER A . n 
A 1 530 GLY 530 530 530 GLY GLY A . n 
A 1 531 VAL 531 531 531 VAL VAL A . n 
A 1 532 ASN 532 532 532 ASN ASN A . n 
A 1 533 GLY 533 533 533 GLY GLY A . n 
A 1 534 VAL 534 534 534 VAL VAL A . n 
A 1 535 ALA 535 535 535 ALA ALA A . n 
A 1 536 ALA 536 536 536 ALA ALA A . n 
A 1 537 ALA 537 537 537 ALA ALA A . n 
A 1 538 LEU 538 538 538 LEU LEU A . n 
A 1 539 ASP 539 539 539 ASP ASP A . n 
A 1 540 THR 540 540 540 THR THR A . n 
A 1 541 PHE 541 541 541 PHE PHE A . n 
A 1 542 GLU 542 542 542 GLU GLU A . n 
A 1 543 ALA 543 543 543 ALA ALA A . n 
A 1 544 ARG 544 544 544 ARG ARG A . n 
A 1 545 ASP 545 545 545 ASP ASP A . n 
A 1 546 TYR 546 546 546 TYR TYR A . n 
A 1 547 VAL 547 547 547 VAL VAL A . n 
A 1 548 ALA 548 548 548 ALA ALA A . n 
A 1 549 ALA 549 549 549 ALA ALA A . n 
A 1 550 ARG 550 550 550 ARG ARG A . n 
A 1 551 CYS 551 551 551 CYS CYS A . n 
A 1 552 THR 552 552 552 THR THR A . n 
A 1 553 HIS 553 553 553 HIS HIS A . n 
A 1 554 PHE 554 554 554 PHE PHE A . n 
A 1 555 LEU 555 555 555 LEU LEU A . n 
A 1 556 LYS 556 556 556 LYS LYS A . n 
A 1 557 PRO 557 557 557 PRO PRO A . n 
A 1 558 LEU 558 558 558 LEU LEU A . n 
A 1 559 LEU 559 559 559 LEU LEU A . n 
A 1 560 GLU 560 560 560 GLU GLU A . n 
A 1 561 ALA 561 561 561 ALA ALA A . n 
A 1 562 GLY 562 562 562 GLY GLY A . n 
A 1 563 THR 563 563 563 THR THR A . n 
A 1 564 MET 564 564 564 MET MET A . n 
A 1 565 GLY 565 565 565 GLY GLY A . n 
A 1 566 THR 566 566 566 THR THR A . n 
A 1 567 ARG 567 567 567 ARG ARG A . n 
A 1 568 GLY 568 568 568 GLY GLY A . n 
A 1 569 SER 569 569 569 SER SER A . n 
A 1 570 ALA 570 570 570 ALA ALA A . n 
A 1 571 SER 571 571 571 SER SER A . n 
A 1 572 VAL 572 572 572 VAL VAL A . n 
A 1 573 PHE 573 573 573 PHE PHE A . n 
A 1 574 ILE 574 574 574 ILE ILE A . n 
A 1 575 PRO 575 575 575 PRO PRO A . n 
A 1 576 HIS 576 576 576 HIS HIS A . n 
A 1 577 VAL 577 577 577 VAL VAL A . n 
A 1 578 THR 578 578 578 THR THR A . n 
A 1 579 GLU 579 579 579 GLU GLU A . n 
A 1 580 ASN 580 580 580 ASN ASN A . n 
A 1 581 TYR 581 581 581 TYR TYR A . n 
A 1 582 LYS 582 582 582 LYS LYS A . n 
A 1 583 ALA 583 583 583 ALA ALA A . n 
A 1 584 PRO 584 584 584 PRO PRO A . n 
A 1 585 SER 585 585 585 SER SER A . n 
A 1 586 ASP 586 586 ?   ?   ?   A . n 
A 1 587 ALA 587 587 ?   ?   ?   A . n 
A 1 588 ALA 588 588 ?   ?   ?   A . n 
A 1 589 SER 589 589 ?   ?   ?   A . n 
A 1 590 GLU 590 590 ?   ?   ?   A . n 
A 1 591 ASP 591 591 ?   ?   ?   A . n 
A 1 592 ALA 592 592 ?   ?   ?   A . n 
A 1 593 PRO 593 593 ?   ?   ?   A . n 
A 1 594 ASP 594 594 594 ASP ASP A . n 
A 1 595 PRO 595 595 595 PRO PRO A . n 
A 1 596 VAL 596 596 596 VAL VAL A . n 
A 1 597 CYS 597 597 597 CYS CYS A . n 
A 1 598 THR 598 598 598 THR THR A . n 
A 1 599 VAL 599 599 599 VAL VAL A . n 
A 1 600 ARG 600 600 600 ARG ARG A . n 
A 1 601 TYR 601 601 601 TYR TYR A . n 
A 1 602 ILE 602 602 602 ILE ILE A . n 
A 1 603 PRO 603 603 603 PRO PRO A . n 
A 1 604 ALA 604 604 604 ALA ALA A . n 
A 1 605 THR 605 605 605 THR THR A . n 
A 1 606 THR 606 606 606 THR THR A . n 
A 1 607 GLU 607 607 607 GLU GLU A . n 
A 1 608 HIS 608 608 608 HIS HIS A . n 
A 1 609 THR 609 609 609 THR THR A . n 
A 1 610 VAL 610 610 610 VAL VAL A . n 
A 1 611 GLN 611 611 611 GLN GLN A . n 
A 1 612 TRP 612 612 612 TRP TRP A . n 
A 1 613 ALA 613 613 613 ALA ALA A . n 
A 1 614 LYS 614 614 614 LYS LYS A . n 
A 1 615 GLY 615 615 615 GLY GLY A . n 
A 1 616 GLU 616 616 616 GLU GLU A . n 
A 1 617 PHE 617 617 617 PHE PHE A . n 
A 1 618 ASP 618 618 618 ASP ASP A . n 
A 1 619 ASP 619 619 619 ASP ASP A . n 
A 1 620 LEU 620 620 620 LEU LEU A . n 
A 1 621 PHE 621 621 621 PHE PHE A . n 
A 1 622 CYS 622 622 622 CYS CYS A . n 
A 1 623 GLU 623 623 623 GLU GLU A . n 
A 1 624 SER 624 624 624 SER SER A . n 
A 1 625 ALA 625 625 625 ALA ALA A . n 
A 1 626 LYS 626 626 626 LYS LYS A . n 
A 1 627 THR 627 627 627 THR THR A . n 
A 1 628 ILE 628 628 628 ILE ILE A . n 
A 1 629 ASN 629 629 629 ASN ASN A . n 
A 1 630 SER 630 630 630 SER SER A . n 
A 1 631 HIS 631 631 631 HIS HIS A . n 
A 1 632 PRO 632 632 632 PRO PRO A . n 
A 1 633 GLN 633 633 633 GLN GLN A . n 
A 1 634 ALA 634 634 634 ALA ALA A . n 
A 1 635 LEU 635 635 635 LEU LEU A . n 
A 1 636 SER 636 636 636 SER SER A . n 
A 1 637 SER 637 637 637 SER SER A . n 
A 1 638 PRO 638 638 638 PRO PRO A . n 
A 1 639 GLU 639 639 639 GLU GLU A . n 
A 1 640 ASP 640 640 640 ASP ASP A . n 
A 1 641 LEU 641 641 641 LEU LEU A . n 
A 1 642 VAL 642 642 642 VAL VAL A . n 
A 1 643 LYS 643 643 643 LYS LYS A . n 
A 1 644 SER 644 644 644 SER SER A . n 
A 1 645 GLN 645 645 645 GLN GLN A . n 
A 1 646 LYS 646 646 646 LYS LYS A . n 
A 1 647 GLN 647 647 647 GLN GLN A . n 
A 1 648 PRO 648 648 648 PRO PRO A . n 
A 1 649 LEU 649 649 649 LEU LEU A . n 
A 1 650 LEU 650 650 650 LEU LEU A . n 
A 1 651 GLN 651 651 651 GLN GLN A . n 
A 1 652 THR 652 652 652 THR THR A . n 
A 1 653 MET 653 653 653 MET MET A . n 
A 1 654 ARG 654 654 654 ARG ARG A . n 
A 1 655 GLY 655 655 655 GLY GLY A . n 
A 1 656 VAL 656 656 656 VAL VAL A . n 
A 1 657 LEU 657 657 657 LEU LEU A . n 
A 1 658 THR 658 658 658 THR THR A . n 
A 1 659 GLU 659 659 659 GLU GLU A . n 
A 1 660 ARG 660 660 660 ARG ARG A . n 
A 1 661 PRO 661 661 661 PRO PRO A . n 
A 1 662 GLN 662 662 662 GLN GLN A . n 
A 1 663 THR 663 663 663 THR THR A . n 
A 1 664 TRP 664 664 664 TRP TRP A . n 
A 1 665 GLN 665 665 665 GLN GLN A . n 
A 1 666 ASP 666 666 666 ASP ASP A . n 
A 1 667 CYS 667 667 667 CYS CYS A . n 
A 1 668 VAL 668 668 668 VAL VAL A . n 
A 1 669 LEU 669 669 669 LEU LEU A . n 
A 1 670 TRP 670 670 670 TRP TRP A . n 
A 1 671 ALA 671 671 671 ALA ALA A . n 
A 1 672 PHE 672 672 672 PHE PHE A . n 
A 1 673 GLY 673 673 673 GLY GLY A . n 
A 1 674 HIS 674 674 674 HIS HIS A . n 
A 1 675 TRP 675 675 675 TRP TRP A . n 
A 1 676 GLN 676 676 676 GLN GLN A . n 
A 1 677 LEU 677 677 677 LEU LEU A . n 
A 1 678 ARG 678 678 678 ARG ARG A . n 
A 1 679 PHE 679 679 679 PHE PHE A . n 
A 1 680 HIS 680 680 680 HIS HIS A . n 
A 1 681 TYR 681 681 681 TYR TYR A . n 
A 1 682 GLY 682 682 682 GLY GLY A . n 
A 1 683 ILE 683 683 683 ILE ILE A . n 
A 1 684 THR 684 684 684 THR THR A . n 
A 1 685 GLN 685 685 685 GLN GLN A . n 
A 1 686 LEU 686 686 686 LEU LEU A . n 
A 1 687 LEU 687 687 687 LEU LEU A . n 
A 1 688 ARG 688 688 688 ARG ARG A . n 
A 1 689 THR 689 689 689 THR THR A . n 
A 1 690 TYR 690 690 690 TYR TYR A . n 
A 1 691 PRO 691 691 691 PRO PRO A . n 
A 1 692 PRO 692 692 692 PRO PRO A . n 
A 1 693 ASP 693 693 693 ASP ASP A . n 
A 1 694 LYS 694 694 694 LYS LYS A . n 
A 1 695 VAL 695 695 695 VAL VAL A . n 
A 1 696 GLN 696 696 ?   ?   ?   A . n 
A 1 697 GLU 697 697 ?   ?   ?   A . n 
A 1 698 ASP 698 698 ?   ?   ?   A . n 
A 1 699 GLY 699 699 ?   ?   ?   A . n 
A 1 700 THR 700 700 ?   ?   ?   A . n 
A 1 701 PRO 701 701 701 PRO PRO A . n 
A 1 702 PHE 702 702 702 PHE PHE A . n 
A 1 703 TRP 703 703 703 TRP TRP A . n 
A 1 704 SER 704 704 704 SER SER A . n 
A 1 705 GLY 705 705 705 GLY GLY A . n 
A 1 706 PRO 706 706 706 PRO PRO A . n 
A 1 707 LYS 707 707 707 LYS LYS A . n 
A 1 708 GLN 708 708 708 GLN GLN A . n 
A 1 709 CYS 709 709 709 CYS CYS A . n 
A 1 710 PRO 710 710 710 PRO PRO A . n 
A 1 711 GLN 711 711 711 GLN GLN A . n 
A 1 712 PRO 712 712 712 PRO PRO A . n 
A 1 713 LEU 713 713 713 LEU LEU A . n 
A 1 714 LYS 714 714 714 LYS LYS A . n 
A 1 715 PHE 715 715 715 PHE PHE A . n 
A 1 716 ASP 716 716 716 ASP ASP A . n 
A 1 717 ALA 717 717 717 ALA ALA A . n 
A 1 718 SER 718 718 718 SER SER A . n 
A 1 719 GLN 719 719 719 GLN GLN A . n 
A 1 720 ASP 720 720 720 ASP ASP A . n 
A 1 721 MET 721 721 721 MET MET A . n 
A 1 722 HIS 722 722 722 HIS HIS A . n 
A 1 723 LEU 723 723 723 LEU LEU A . n 
A 1 724 LEU 724 724 724 LEU LEU A . n 
A 1 725 TYR 725 725 725 TYR TYR A . n 
A 1 726 VAL 726 726 726 VAL VAL A . n 
A 1 727 LEU 727 727 727 LEU LEU A . n 
A 1 728 ALA 728 728 728 ALA ALA A . n 
A 1 729 ALA 729 729 729 ALA ALA A . n 
A 1 730 ALA 730 730 730 ALA ALA A . n 
A 1 731 ASN 731 731 731 ASN ASN A . n 
A 1 732 LEU 732 732 732 LEU LEU A . n 
A 1 733 TYR 733 733 733 TYR TYR A . n 
A 1 734 ALA 734 734 734 ALA ALA A . n 
A 1 735 GLN 735 735 735 GLN GLN A . n 
A 1 736 MET 736 736 736 MET MET A . n 
A 1 737 HIS 737 737 737 HIS HIS A . n 
A 1 738 GLY 738 738 738 GLY GLY A . n 
A 1 739 LEU 739 739 739 LEU LEU A . n 
A 1 740 PRO 740 740 740 PRO PRO A . n 
A 1 741 GLY 741 741 741 GLY GLY A . n 
A 1 742 SER 742 742 742 SER SER A . n 
A 1 743 GLN 743 743 743 GLN GLN A . n 
A 1 744 ASP 744 744 744 ASP ASP A . n 
A 1 745 GLN 745 745 745 GLN GLN A . n 
A 1 746 THR 746 746 746 THR THR A . n 
A 1 747 ALA 747 747 747 ALA ALA A . n 
A 1 748 LEU 748 748 748 LEU LEU A . n 
A 1 749 ARG 749 749 749 ARG ARG A . n 
A 1 750 GLY 750 750 750 GLY GLY A . n 
A 1 751 LEU 751 751 751 LEU LEU A . n 
A 1 752 LEU 752 752 752 LEU LEU A . n 
A 1 753 ASN 753 753 753 ASN ASN A . n 
A 1 754 LEU 754 754 754 LEU LEU A . n 
A 1 755 LEU 755 755 755 LEU LEU A . n 
A 1 756 PRO 756 756 756 PRO PRO A . n 
A 1 757 LEU 757 757 757 LEU LEU A . n 
A 1 758 PRO 758 758 758 PRO PRO A . n 
A 1 759 ASP 759 759 759 ASP ASP A . n 
A 1 760 PRO 760 760 760 PRO PRO A . n 
A 1 761 GLN 761 761 761 GLN GLN A . n 
A 1 762 ASN 762 762 762 ASN ASN A . n 
A 1 763 LEU 763 763 763 LEU LEU A . n 
A 1 764 ASP 764 764 764 ASP ASP A . n 
A 1 765 ARG 765 765 765 ARG ARG A . n 
A 1 766 ILE 766 766 766 ILE ILE A . n 
A 1 767 PHE 767 767 767 PHE PHE A . n 
A 1 768 ALA 768 768 768 ALA ALA A . n 
A 1 769 SER 769 769 769 SER SER A . n 
A 1 770 GLU 770 770 770 GLU GLU A . n 
A 1 771 LEU 771 771 771 LEU LEU A . n 
A 1 772 GLU 772 772 772 GLU GLU A . n 
A 1 773 LEU 773 773 773 LEU LEU A . n 
A 1 774 ASP 774 774 774 ASP ASP A . n 
A 1 775 SER 775 775 775 SER SER A . n 
A 1 776 PRO 776 776 776 PRO PRO A . n 
A 1 777 SER 777 777 777 SER SER A . n 
A 1 778 GLY 778 778 778 GLY GLY A . n 
A 1 779 CYS 779 779 779 CYS CYS A . n 
A 1 780 LYS 780 780 780 LYS LYS A . n 
A 1 781 GLN 781 781 781 GLN GLN A . n 
A 1 782 LEU 782 782 782 LEU LEU A . n 
A 1 783 HIS 783 783 783 HIS HIS A . n 
A 1 784 GLU 784 784 784 GLU GLU A . n 
A 1 785 ASP 785 785 785 ASP ASP A . n 
A 1 786 LEU 786 786 786 LEU LEU A . n 
A 1 787 LYS 787 787 787 LYS LYS A . n 
A 1 788 THR 788 788 788 THR THR A . n 
A 1 789 TRP 789 789 789 TRP TRP A . n 
A 1 790 SER 790 790 790 SER SER A . n 
A 1 791 LYS 791 791 791 LYS LYS A . n 
A 1 792 GLY 792 792 792 GLY GLY A . n 
A 1 793 PRO 793 793 793 PRO PRO A . n 
A 1 794 PRO 794 794 794 PRO PRO A . n 
A 1 795 LEU 795 795 795 LEU LEU A . n 
A 1 796 LYS 796 796 796 LYS LYS A . n 
A 1 797 PRO 797 797 797 PRO PRO A . n 
A 1 798 LEU 798 798 798 LEU LEU A . n 
A 1 799 THR 799 799 799 THR THR A . n 
A 1 800 PHE 800 800 800 PHE PHE A . n 
A 1 801 GLU 801 801 ?   ?   ?   A . n 
A 1 802 LYS 802 802 ?   ?   ?   A . n 
A 1 803 ASP 803 803 ?   ?   ?   A . n 
A 1 804 ASN 804 804 ?   ?   ?   A . n 
A 1 805 ASP 805 805 ?   ?   ?   A . n 
A 1 806 SER 806 806 ?   ?   ?   A . n 
A 1 807 ASN 807 807 807 ASN ASN A . n 
A 1 808 PHE 808 808 808 PHE PHE A . n 
A 1 809 HIS 809 809 809 HIS HIS A . n 
A 1 810 VAL 810 810 810 VAL VAL A . n 
A 1 811 ASP 811 811 811 ASP ASP A . n 
A 1 812 PHE 812 812 812 PHE PHE A . n 
A 1 813 VAL 813 813 813 VAL VAL A . n 
A 1 814 VAL 814 814 814 VAL VAL A . n 
A 1 815 ALA 815 815 815 ALA ALA A . n 
A 1 816 ALA 816 816 816 ALA ALA A . n 
A 1 817 ALA 817 817 817 ALA ALA A . n 
A 1 818 SER 818 818 818 SER SER A . n 
A 1 819 LEU 819 819 819 LEU LEU A . n 
A 1 820 ARG 820 820 820 ARG ARG A . n 
A 1 821 ALA 821 821 821 ALA ALA A . n 
A 1 822 GLN 822 822 822 GLN GLN A . n 
A 1 823 ASN 823 823 823 ASN ASN A . n 
A 1 824 TYR 824 824 824 TYR TYR A . n 
A 1 825 GLY 825 825 825 GLY GLY A . n 
A 1 826 ILE 826 826 826 ILE ILE A . n 
A 1 827 PRO 827 827 827 PRO PRO A . n 
A 1 828 VAL 828 828 828 VAL VAL A . n 
A 1 829 ALA 829 829 829 ALA ALA A . n 
A 1 830 SER 830 830 830 SER SER A . n 
A 1 831 HIS 831 831 831 HIS HIS A . n 
A 1 832 ALA 832 832 832 ALA ALA A . n 
A 1 833 GLU 833 833 833 GLU GLU A . n 
A 1 834 THR 834 834 834 THR THR A . n 
A 1 835 LYS 835 835 835 LYS LYS A . n 
A 1 836 ARG 836 836 836 ARG ARG A . n 
A 1 837 ILE 837 837 837 ILE ILE A . n 
A 1 838 VAL 838 838 838 VAL VAL A . n 
A 1 839 GLY 839 839 839 GLY GLY A . n 
A 1 840 ARG 840 840 840 ARG ARG A . n 
A 1 841 ILE 841 841 841 ILE ILE A . n 
A 1 842 ILE 842 842 842 ILE ILE A . n 
A 1 843 PRO 843 843 843 PRO PRO A . n 
A 1 844 ALA 844 844 844 ALA ALA A . n 
A 1 845 VAL 845 845 845 VAL VAL A . n 
A 1 846 VAL 846 846 846 VAL VAL A . n 
A 1 847 THR 847 847 847 THR THR A . n 
A 1 848 THR 848 848 848 THR THR A . n 
A 1 849 THR 849 849 849 THR THR A . n 
A 1 850 ALA 850 850 850 ALA ALA A . n 
A 1 851 ALA 851 851 851 ALA ALA A . n 
A 1 852 VAL 852 852 852 VAL VAL A . n 
A 1 853 ALA 853 853 853 ALA ALA A . n 
A 1 854 GLY 854 854 854 GLY GLY A . n 
A 1 855 LEU 855 855 855 LEU LEU A . n 
A 1 856 VAL 856 856 856 VAL VAL A . n 
A 1 857 GLY 857 857 857 GLY GLY A . n 
A 1 858 LEU 858 858 858 LEU LEU A . n 
A 1 859 GLU 859 859 859 GLU GLU A . n 
A 1 860 LEU 860 860 860 LEU LEU A . n 
A 1 861 TYR 861 861 861 TYR TYR A . n 
A 1 862 LYS 862 862 862 LYS LYS A . n 
A 1 863 VAL 863 863 863 VAL VAL A . n 
A 1 864 VAL 864 864 864 VAL VAL A . n 
A 1 865 GLY 865 865 865 GLY GLY A . n 
A 1 866 GLY 866 866 866 GLY GLY A . n 
A 1 867 PRO 867 867 867 PRO PRO A . n 
A 1 868 ARG 868 868 868 ARG ARG A . n 
A 1 869 PRO 869 869 869 PRO PRO A . n 
A 1 870 ARG 870 870 870 ARG ARG A . n 
A 1 871 HIS 871 871 871 HIS HIS A . n 
A 1 872 ALA 872 872 872 ALA ALA A . n 
A 1 873 PHE 873 873 873 PHE PHE A . n 
A 1 874 ARG 874 874 874 ARG ARG A . n 
A 1 875 HIS 875 875 875 HIS HIS A . n 
A 1 876 SER 876 876 876 SER SER A . n 
A 1 877 TYR 877 877 877 TYR TYR A . n 
A 1 878 LEU 878 878 878 LEU LEU A . n 
A 1 879 HIS 879 879 879 HIS HIS A . n 
A 1 880 LEU 880 880 880 LEU LEU A . n 
A 1 881 ALA 881 881 881 ALA ALA A . n 
A 1 882 GLU 882 882 882 GLU GLU A . n 
A 1 883 ASN 883 883 883 ASN ASN A . n 
A 1 884 TYR 884 884 884 TYR TYR A . n 
A 1 885 PHE 885 885 885 PHE PHE A . n 
A 1 886 SER 886 886 886 SER SER A . n 
A 1 887 ARG 887 887 887 ARG ARG A . n 
A 1 888 TRP 888 888 888 TRP TRP A . n 
A 1 889 VAL 889 889 889 VAL VAL A . n 
A 1 890 PRO 890 890 890 PRO PRO A . n 
A 1 891 LYS 891 891 891 LYS LYS A . n 
A 1 892 ALA 892 892 892 ALA ALA A . n 
A 1 893 PRO 893 893 893 PRO PRO A . n 
A 1 894 ASP 894 894 894 ASP ASP A . n 
A 1 895 ILE 895 895 895 ILE ILE A . n 
A 1 896 GLN 896 896 896 GLN GLN A . n 
A 1 897 LYS 897 897 897 LYS LYS A . n 
A 1 898 PHE 898 898 898 PHE PHE A . n 
A 1 899 HIS 899 899 899 HIS HIS A . n 
A 1 900 HIS 900 900 900 HIS HIS A . n 
A 1 901 LEU 901 901 901 LEU LEU A . n 
A 1 902 LYS 902 902 902 LYS LYS A . n 
A 1 903 TRP 903 903 903 TRP TRP A . n 
A 1 904 THR 904 904 904 THR THR A . n 
A 1 905 CYS 905 905 905 CYS CYS A . n 
A 1 906 TRP 906 906 906 TRP TRP A . n 
A 1 907 ASP 907 907 907 ASP ASP A . n 
A 1 908 ARG 908 908 908 ARG ARG A . n 
A 1 909 LEU 909 909 909 LEU LEU A . n 
A 1 910 GLU 910 910 910 GLU GLU A . n 
A 1 911 VAL 911 911 911 VAL VAL A . n 
A 1 912 PRO 912 912 912 PRO PRO A . n 
A 1 913 ALA 913 913 913 ALA ALA A . n 
A 1 914 GLY 914 914 914 GLY GLY A . n 
A 1 915 GLN 915 915 915 GLN GLN A . n 
A 1 916 PRO 916 916 916 PRO PRO A . n 
A 1 917 GLU 917 917 917 GLU GLU A . n 
A 1 918 ARG 918 918 918 ARG ARG A . n 
A 1 919 THR 919 919 919 THR THR A . n 
A 1 920 LEU 920 920 920 LEU LEU A . n 
A 1 921 GLU 921 921 921 GLU GLU A . n 
A 1 922 SER 922 922 922 SER SER A . n 
A 1 923 LEU 923 923 923 LEU LEU A . n 
A 1 924 LEU 924 924 924 LEU LEU A . n 
A 1 925 ALA 925 925 925 ALA ALA A . n 
A 1 926 HIS 926 926 926 HIS HIS A . n 
A 1 927 ILE 927 927 927 ILE ILE A . n 
A 1 928 GLN 928 928 928 GLN GLN A . n 
A 1 929 GLU 929 929 929 GLU GLU A . n 
A 1 930 LEU 930 930 930 LEU LEU A . n 
A 1 931 GLN 931 931 931 GLN GLN A . n 
A 1 932 GLY 932 932 932 GLY GLY A . n 
A 1 933 LEU 933 933 933 LEU LEU A . n 
A 1 934 ARG 934 934 934 ARG ARG A . n 
A 1 935 VAL 935 935 935 VAL VAL A . n 
A 1 936 THR 936 936 936 THR THR A . n 
A 1 937 MET 937 937 937 MET MET A . n 
A 1 938 LEU 938 938 938 LEU LEU A . n 
A 1 939 LEU 939 939 939 LEU LEU A . n 
A 1 940 HIS 940 940 940 HIS HIS A . n 
A 1 941 GLY 941 941 941 GLY GLY A . n 
A 1 942 SER 942 942 942 SER SER A . n 
A 1 943 ALA 943 943 943 ALA ALA A . n 
A 1 944 LEU 944 944 944 LEU LEU A . n 
A 1 945 LEU 945 945 945 LEU LEU A . n 
A 1 946 TYR 946 946 946 TYR TYR A . n 
A 1 947 SER 947 947 947 SER SER A . n 
A 1 948 ALA 948 948 948 ALA ALA A . n 
A 1 949 GLY 949 949 949 GLY GLY A . n 
A 1 950 TRP 950 950 950 TRP TRP A . n 
A 1 951 SER 951 951 951 SER SER A . n 
A 1 952 GLU 952 952 952 GLU GLU A . n 
A 1 953 GLU 953 953 953 GLU GLU A . n 
A 1 954 LYS 954 954 954 LYS LYS A . n 
A 1 955 GLN 955 955 955 GLN GLN A . n 
A 1 956 THR 956 956 956 THR THR A . n 
A 1 957 GLN 957 957 957 GLN GLN A . n 
A 1 958 HIS 958 958 958 HIS HIS A . n 
A 1 959 LEU 959 959 959 LEU LEU A . n 
A 1 960 SER 960 960 960 SER SER A . n 
A 1 961 ARG 961 961 961 ARG ARG A . n 
A 1 962 ARG 962 962 962 ARG ARG A . n 
A 1 963 VAL 963 963 963 VAL VAL A . n 
A 1 964 THR 964 964 964 THR THR A . n 
A 1 965 ASP 965 965 965 ASP ASP A . n 
A 1 966 LEU 966 966 966 LEU LEU A . n 
A 1 967 VAL 967 967 967 VAL VAL A . n 
A 1 968 LYS 968 968 968 LYS LYS A . n 
A 1 969 LYS 969 969 969 LYS LYS A . n 
A 1 970 VAL 970 970 970 VAL VAL A . n 
A 1 971 PRO 971 971 971 PRO PRO A . n 
A 1 972 GLY 972 972 972 GLY GLY A . n 
A 1 973 GLN 973 973 973 GLN GLN A . n 
A 1 974 ARG 974 974 974 ARG ARG A . n 
A 1 975 VAL 975 975 975 VAL VAL A . n 
A 1 976 LEU 976 976 976 LEU LEU A . n 
A 1 977 VAL 977 977 977 VAL VAL A . n 
A 1 978 LEU 978 978 978 LEU LEU A . n 
A 1 979 GLU 979 979 979 GLU GLU A . n 
A 1 980 LEU 980 980 980 LEU LEU A . n 
A 1 981 GLY 981 981 981 GLY GLY A . n 
A 1 982 TYR 982 982 982 TYR TYR A . n 
A 1 983 GLU 983 983 983 GLU GLU A . n 
A 1 984 GLY 984 984 984 GLY GLY A . n 
A 1 985 GLU 985 985 985 GLU GLU A . n 
A 1 986 GLU 986 986 986 GLU GLU A . n 
A 1 987 ASP 987 987 987 ASP ASP A . n 
A 1 988 ASP 988 988 988 ASP ASP A . n 
A 1 989 THR 989 989 989 THR THR A . n 
A 1 990 ASN 990 990 990 ASN ASN A . n 
A 1 991 PHE 991 991 991 PHE PHE A . n 
A 1 992 PRO 992 992 992 PRO PRO A . n 
A 1 993 ARG 993 993 993 ARG ARG A . n 
A 1 994 LEU 994 994 994 LEU LEU A . n 
A 1 995 HIS 995 995 995 HIS HIS A . n 
A 1 996 TYR 996 996 996 TYR TYR A . n 
A 1 997 LYS 997 997 997 LYS LYS A . n 
A 1 998 LEU 998 998 998 LEU LEU A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   ALA 2   2   ?   ?   ?   B . n 
B 2 3   ALA 3   3   3   ALA ALA B . n 
B 2 4   SER 4   4   4   SER SER B . n 
B 2 5   LYS 5   5   5   LYS LYS B . n 
B 2 6   ARG 6   6   6   ARG ARG B . n 
B 2 7   VAL 7   7   7   VAL VAL B . n 
B 2 8   ALA 8   8   8   ALA ALA B . n 
B 2 9   LYS 9   9   9   LYS LYS B . n 
B 2 10  GLU 10  10  10  GLU GLU B . n 
B 2 11  LEU 11  11  11  LEU LEU B . n 
B 2 12  GLU 12  12  12  GLU GLU B . n 
B 2 13  ASP 13  13  13  ASP ASP B . n 
B 2 14  LEU 14  14  14  LEU LEU B . n 
B 2 15  GLN 15  15  15  GLN GLN B . n 
B 2 16  LYS 16  16  16  LYS LYS B . n 
B 2 17  GLU 17  17  17  GLU GLU B . n 
B 2 18  LEU 18  18  18  LEU LEU B . n 
B 2 19  PRO 19  19  19  PRO PRO B . n 
B 2 20  LYS 20  20  20  LYS LYS B . n 
B 2 21  TYR 21  21  21  TYR TYR B . n 
B 2 22  LEU 22  22  22  LEU LEU B . n 
B 2 23  ARG 23  23  23  ARG ARG B . n 
B 2 24  ASN 24  24  24  ASN ASN B . n 
B 2 25  LEU 25  25  25  LEU LEU B . n 
B 2 26  SER 26  26  26  SER SER B . n 
B 2 27  SER 27  27  27  SER SER B . n 
B 2 28  GLU 28  28  28  GLU GLU B . n 
B 2 29  GLU 29  29  29  GLU GLU B . n 
B 2 30  ASP 30  30  30  ASP ASP B . n 
B 2 31  ASN 31  31  31  ASN ASN B . n 
B 2 32  VAL 32  32  32  VAL VAL B . n 
B 2 33  LEU 33  33  33  LEU LEU B . n 
B 2 34  VAL 34  34  34  VAL VAL B . n 
B 2 35  TRP 35  35  35  TRP TRP B . n 
B 2 36  HIS 36  36  36  HIS HIS B . n 
B 2 37  ALA 37  37  37  ALA ALA B . n 
B 2 38  LEU 38  38  38  LEU LEU B . n 
B 2 39  LEU 39  39  39  LEU LEU B . n 
B 2 40  LEU 40  40  40  LEU LEU B . n 
B 2 41  PRO 41  41  41  PRO PRO B . n 
B 2 42  GLU 42  42  42  GLU GLU B . n 
B 2 43  ARG 43  43  43  ARG ARG B . n 
B 2 44  PRO 44  44  44  PRO PRO B . n 
B 2 45  PRO 45  45  45  PRO PRO B . n 
B 2 46  TYR 46  46  46  TYR TYR B . n 
B 2 47  ASN 47  47  47  ASN ASN B . n 
B 2 48  LEU 48  48  48  LEU LEU B . n 
B 2 49  LYS 49  49  49  LYS LYS B . n 
B 2 50  ALA 50  50  50  ALA ALA B . n 
B 2 51  PHE 51  51  51  PHE PHE B . n 
B 2 52  ARG 52  52  52  ARG ARG B . n 
B 2 53  LEU 53  53  53  LEU LEU B . n 
B 2 54  SER 54  54  54  SER SER B . n 
B 2 55  ILE 55  55  55  ILE ILE B . n 
B 2 56  SER 56  56  56  SER SER B . n 
B 2 57  PHE 57  57  57  PHE PHE B . n 
B 2 58  PRO 58  58  58  PRO PRO B . n 
B 2 59  ARG 59  59  59  ARG ARG B . n 
B 2 60  GLU 60  60  60  GLU GLU B . n 
B 2 61  TYR 61  61  61  TYR TYR B . n 
B 2 62  PRO 62  62  62  PRO PRO B . n 
B 2 63  PHE 63  63  63  PHE PHE B . n 
B 2 64  GLN 64  64  64  GLN GLN B . n 
B 2 65  PRO 65  65  65  PRO PRO B . n 
B 2 66  PRO 66  66  66  PRO PRO B . n 
B 2 67  THR 67  67  67  THR THR B . n 
B 2 68  VAL 68  68  68  VAL VAL B . n 
B 2 69  LYS 69  69  69  LYS LYS B . n 
B 2 70  PHE 70  70  70  PHE PHE B . n 
B 2 71  THR 71  71  71  THR THR B . n 
B 2 72  THR 72  72  72  THR THR B . n 
B 2 73  ARG 73  73  73  ARG ARG B . n 
B 2 74  ILE 74  74  74  ILE ILE B . n 
B 2 75  TYR 75  75  75  TYR TYR B . n 
B 2 76  HIS 76  76  76  HIS HIS B . n 
B 2 77  PRO 77  77  77  PRO PRO B . n 
B 2 78  ASN 78  78  78  ASN ASN B . n 
B 2 79  VAL 79  79  79  VAL VAL B . n 
B 2 80  ASP 80  80  80  ASP ASP B . n 
B 2 81  ARG 81  81  81  ARG ARG B . n 
B 2 82  ASP 82  82  82  ASP ASP B . n 
B 2 83  GLY 83  83  83  GLY GLY B . n 
B 2 84  ARG 84  84  84  ARG ARG B . n 
B 2 85  VAL 85  85  85  VAL VAL B . n 
B 2 86  CYS 86  86  86  CYS CYS B . n 
B 2 87  LEU 87  87  87  LEU LEU B . n 
B 2 88  PRO 88  88  88  PRO PRO B . n 
B 2 89  ILE 89  89  89  ILE ILE B . n 
B 2 90  ILE 90  90  90  ILE ILE B . n 
B 2 91  SER 91  91  91  SER SER B . n 
B 2 92  LYS 92  92  92  LYS LYS B . n 
B 2 93  LYS 93  93  93  LYS LYS B . n 
B 2 94  ASN 94  94  94  ASN ASN B . n 
B 2 95  TRP 95  95  95  TRP TRP B . n 
B 2 96  LYS 96  96  96  LYS LYS B . n 
B 2 97  ALA 97  97  97  ALA ALA B . n 
B 2 98  SER 98  98  98  SER SER B . n 
B 2 99  THR 99  99  99  THR THR B . n 
B 2 100 ARG 100 100 100 ARG ARG B . n 
B 2 101 THR 101 101 101 THR THR B . n 
B 2 102 SER 102 102 102 SER SER B . n 
B 2 103 GLN 103 103 103 GLN GLN B . n 
B 2 104 VAL 104 104 104 VAL VAL B . n 
B 2 105 LEU 105 105 105 LEU LEU B . n 
B 2 106 GLU 106 106 106 GLU GLU B . n 
B 2 107 ALA 107 107 107 ALA ALA B . n 
B 2 108 LEU 108 108 108 LEU LEU B . n 
B 2 109 ASN 109 109 109 ASN ASN B . n 
B 2 110 MET 110 110 110 MET MET B . n 
B 2 111 LEU 111 111 111 LEU LEU B . n 
B 2 112 VAL 112 112 112 VAL VAL B . n 
B 2 113 ASN 113 113 113 ASN ASN B . n 
B 2 114 GLN 114 114 114 GLN GLN B . n 
B 2 115 PRO 115 115 115 PRO PRO B . n 
B 2 116 GLU 116 116 116 GLU GLU B . n 
B 2 117 PRO 117 117 117 PRO PRO B . n 
B 2 118 GLY 118 118 118 GLY GLY B . n 
B 2 119 GLN 119 119 119 GLN GLN B . n 
B 2 120 PRO 120 120 120 PRO PRO B . n 
B 2 121 VAL 121 121 121 VAL VAL B . n 
B 2 122 ARG 122 122 122 ARG ARG B . n 
B 2 123 LEU 123 123 123 LEU LEU B . n 
B 2 124 GLU 124 124 124 GLU GLU B . n 
B 2 125 LEU 125 125 125 LEU LEU B . n 
B 2 126 ALA 126 126 126 ALA ALA B . n 
B 2 127 GLU 127 127 127 GLU GLU B . n 
B 2 128 GLN 128 128 128 GLN GLN B . n 
B 2 129 LEU 129 129 129 LEU LEU B . n 
B 2 130 THR 130 130 130 THR THR B . n 
B 2 131 GLN 131 131 131 GLN GLN B . n 
B 2 132 ASP 132 132 132 ASP ASP B . n 
B 2 133 PRO 133 133 133 PRO PRO B . n 
B 2 134 GLU 134 134 134 GLU GLU B . n 
B 2 135 LEU 135 135 135 LEU LEU B . n 
B 2 136 PHE 136 136 136 PHE PHE B . n 
B 2 137 ASP 137 137 137 ASP ASP B . n 
B 2 138 GLN 138 138 138 GLN GLN B . n 
B 2 139 MET 139 139 139 MET MET B . n 
B 2 140 ALA 140 140 140 ALA ALA B . n 
B 2 141 GLN 141 141 141 GLN GLN B . n 
B 2 142 GLU 142 142 142 GLU GLU B . n 
B 2 143 PHE 143 143 143 PHE PHE B . n 
B 2 144 THR 144 144 144 THR THR B . n 
B 2 145 LEU 145 145 145 LEU LEU B . n 
B 2 146 GLN 146 146 146 GLN GLN B . n 
B 2 147 PHE 147 147 147 PHE PHE B . n 
B 2 148 GLY 148 148 148 GLY GLY B . n 
B 2 149 VAL 149 149 149 VAL VAL B . n 
B 2 150 ASP 150 150 150 ASP ASP B . n 
B 2 151 ARG 151 151 151 ARG ARG B . n 
B 2 152 PRO 152 152 152 PRO PRO B . n 
B 2 153 SER 153 153 ?   ?   ?   B . n 
B 2 154 HIS 154 154 ?   ?   ?   B . n 
B 2 155 HIS 155 155 ?   ?   ?   B . n 
B 2 156 HIS 156 156 ?   ?   ?   B . n 
B 2 157 HIS 157 157 ?   ?   ?   B . n 
B 2 158 HIS 158 158 ?   ?   ?   B . n 
B 2 159 HIS 159 159 ?   ?   ?   B . n 
C 3 1   MET 1   1   ?   ?   ?   C . n 
C 3 2   GLY 2   2   ?   ?   ?   C . n 
C 3 3   GLY 3   3   ?   ?   ?   C . n 
C 3 4   ASP 4   4   ?   ?   ?   C . n 
C 3 5   LEU 5   5   ?   ?   ?   C . n 
C 3 6   THR 6   6   ?   ?   ?   C . n 
C 3 7   VAL 7   7   ?   ?   ?   C . n 
C 3 8   LYS 8   8   ?   ?   ?   C . n 
C 3 9   MET 9   9   ?   ?   ?   C . n 
C 3 10  LEU 10  10  ?   ?   ?   C . n 
C 3 11  GLY 11  11  ?   ?   ?   C . n 
C 3 12  GLY 12  12  ?   ?   ?   C . n 
C 3 13  GLN 13  13  ?   ?   ?   C . n 
C 3 14  GLU 14  14  ?   ?   ?   C . n 
C 3 15  ILE 15  15  ?   ?   ?   C . n 
C 3 16  LEU 16  16  ?   ?   ?   C . n 
C 3 17  VAL 17  17  ?   ?   ?   C . n 
C 3 18  PRO 18  18  ?   ?   ?   C . n 
C 3 19  LEU 19  19  ?   ?   ?   C . n 
C 3 20  ARG 20  20  ?   ?   ?   C . n 
C 3 21  ASP 21  21  ?   ?   ?   C . n 
C 3 22  SER 22  22  ?   ?   ?   C . n 
C 3 23  MET 23  23  ?   ?   ?   C . n 
C 3 24  THR 24  24  ?   ?   ?   C . n 
C 3 25  VAL 25  25  ?   ?   ?   C . n 
C 3 26  SER 26  26  ?   ?   ?   C . n 
C 3 27  GLU 27  27  ?   ?   ?   C . n 
C 3 28  LEU 28  28  ?   ?   ?   C . n 
C 3 29  LYS 29  29  ?   ?   ?   C . n 
C 3 30  GLN 30  30  ?   ?   ?   C . n 
C 3 31  PHE 31  31  ?   ?   ?   C . n 
C 3 32  ILE 32  32  ?   ?   ?   C . n 
C 3 33  ALA 33  33  ?   ?   ?   C . n 
C 3 34  GLN 34  34  ?   ?   ?   C . n 
C 3 35  LYS 35  35  ?   ?   ?   C . n 
C 3 36  ILE 36  36  ?   ?   ?   C . n 
C 3 37  ASN 37  37  ?   ?   ?   C . n 
C 3 38  VAL 38  38  ?   ?   ?   C . n 
C 3 39  PRO 39  39  ?   ?   ?   C . n 
C 3 40  ALA 40  40  ?   ?   ?   C . n 
C 3 41  PHE 41  41  ?   ?   ?   C . n 
C 3 42  GLN 42  42  ?   ?   ?   C . n 
C 3 43  GLN 43  43  ?   ?   ?   C . n 
C 3 44  ARG 44  44  ?   ?   ?   C . n 
C 3 45  LEU 45  45  ?   ?   ?   C . n 
C 3 46  ALA 46  46  ?   ?   ?   C . n 
C 3 47  HIS 47  47  ?   ?   ?   C . n 
C 3 48  LEU 48  48  ?   ?   ?   C . n 
C 3 49  ASP 49  49  ?   ?   ?   C . n 
C 3 50  SER 50  50  ?   ?   ?   C . n 
C 3 51  ARG 51  51  ?   ?   ?   C . n 
C 3 52  GLU 52  52  ?   ?   ?   C . n 
C 3 53  VAL 53  53  ?   ?   ?   C . n 
C 3 54  LEU 54  54  ?   ?   ?   C . n 
C 3 55  GLN 55  55  ?   ?   ?   C . n 
C 3 56  GLU 56  56  ?   ?   ?   C . n 
C 3 57  GLY 57  57  ?   ?   ?   C . n 
C 3 58  VAL 58  58  ?   ?   ?   C . n 
C 3 59  PRO 59  59  ?   ?   ?   C . n 
C 3 60  LEU 60  60  ?   ?   ?   C . n 
C 3 61  VAL 61  61  ?   ?   ?   C . n 
C 3 62  LEU 62  62  ?   ?   ?   C . n 
C 3 63  GLN 63  63  ?   ?   ?   C . n 
C 3 64  GLY 64  64  ?   ?   ?   C . n 
C 3 65  LEU 65  65  ?   ?   ?   C . n 
C 3 66  ARG 66  66  ?   ?   ?   C . n 
C 3 67  ALA 67  67  ?   ?   ?   C . n 
C 3 68  GLY 68  68  ?   ?   ?   C . n 
C 3 69  SER 69  69  ?   ?   ?   C . n 
C 3 70  THR 70  70  ?   ?   ?   C . n 
C 3 71  VAL 71  71  ?   ?   ?   C . n 
C 3 72  LEU 72  72  ?   ?   ?   C . n 
C 3 73  LEU 73  73  ?   ?   ?   C . n 
C 3 74  VAL 74  74  ?   ?   ?   C . n 
C 3 75  VAL 75  75  ?   ?   ?   C . n 
C 3 76  GLN 76  76  ?   ?   ?   C . n 
C 3 77  ASN 77  77  ?   ?   ?   C . n 
C 3 78  CYS 78  78  ?   ?   ?   C . n 
C 3 79  ILE 79  79  ?   ?   ?   C . n 
C 3 80  SER 80  80  80  SER SER C . n 
C 3 81  ILE 81  81  81  ILE ILE C . n 
C 3 82  LEU 82  82  82  LEU LEU C . n 
C 3 83  VAL 83  83  83  VAL VAL C . n 
C 3 84  ARG 84  84  84  ARG ARG C . n 
C 3 85  ASN 85  85  85  ASN ASN C . n 
C 3 86  ASP 86  86  86  ASP ASP C . n 
C 3 87  LYS 87  87  87  LYS LYS C . n 
C 3 88  GLY 88  88  88  GLY GLY C . n 
C 3 89  ARG 89  89  89  ARG ARG C . n 
C 3 90  SER 90  90  90  SER SER C . n 
C 3 91  SER 91  91  91  SER SER C . n 
C 3 92  PRO 92  92  92  PRO PRO C . n 
C 3 93  TYR 93  93  93  TYR TYR C . n 
C 3 94  GLU 94  94  94  GLU GLU C . n 
C 3 95  VAL 95  95  95  VAL VAL C . n 
C 3 96  GLN 96  96  96  GLN GLN C . n 
C 3 97  LEU 97  97  97  LEU LEU C . n 
C 3 98  LYS 98  98  98  LYS LYS C . n 
C 3 99  GLN 99  99  99  GLN GLN C . n 
C 3 100 THR 100 100 100 THR THR C . n 
C 3 101 VAL 101 101 101 VAL VAL C . n 
C 3 102 ALA 102 102 102 ALA ALA C . n 
C 3 103 GLU 103 103 103 GLU GLU C . n 
C 3 104 LEU 104 104 104 LEU LEU C . n 
C 3 105 LYS 105 105 105 LYS LYS C . n 
C 3 106 GLN 106 106 106 GLN GLN C . n 
C 3 107 GLN 107 107 107 GLN GLN C . n 
C 3 108 VAL 108 108 108 VAL VAL C . n 
C 3 109 CYS 109 109 109 CYS CYS C . n 
C 3 110 GLN 110 110 110 GLN GLN C . n 
C 3 111 LYS 111 111 111 LYS LYS C . n 
C 3 112 GLU 112 112 112 GLU GLU C . n 
C 3 113 ARG 113 113 113 ARG ARG C . n 
C 3 114 VAL 114 114 114 VAL VAL C . n 
C 3 115 GLN 115 115 115 GLN GLN C . n 
C 3 116 ALA 116 116 116 ALA ALA C . n 
C 3 117 ASP 117 117 117 ASP ASP C . n 
C 3 118 GLN 118 118 118 GLN GLN C . n 
C 3 119 PHE 119 119 119 PHE PHE C . n 
C 3 120 TRP 120 120 120 TRP TRP C . n 
C 3 121 LEU 121 121 121 LEU LEU C . n 
C 3 122 SER 122 122 122 SER SER C . n 
C 3 123 PHE 123 123 123 PHE PHE C . n 
C 3 124 GLU 124 124 124 GLU GLU C . n 
C 3 125 GLY 125 125 125 GLY GLY C . n 
C 3 126 ARG 126 126 126 ARG ARG C . n 
C 3 127 PRO 127 127 127 PRO PRO C . n 
C 3 128 MET 128 128 128 MET MET C . n 
C 3 129 ASP 129 129 129 ASP ASP C . n 
C 3 130 ASP 130 130 130 ASP ASP C . n 
C 3 131 GLU 131 131 131 GLU GLU C . n 
C 3 132 HIS 132 132 132 HIS HIS C . n 
C 3 133 PRO 133 133 133 PRO PRO C . n 
C 3 134 LEU 134 134 134 LEU LEU C . n 
C 3 135 GLU 135 135 135 GLU GLU C . n 
C 3 136 GLU 136 136 136 GLU GLU C . n 
C 3 137 TYR 137 137 137 TYR TYR C . n 
C 3 138 GLY 138 138 138 GLY GLY C . n 
C 3 139 LEU 139 139 139 LEU LEU C . n 
C 3 140 MET 140 140 140 MET MET C . n 
C 3 141 LYS 141 141 141 LYS LYS C . n 
C 3 142 GLY 142 142 142 GLY GLY C . n 
C 3 143 CYS 143 143 143 CYS CYS C . n 
C 3 144 THR 144 144 144 THR THR C . n 
C 3 145 VAL 145 145 145 VAL VAL C . n 
C 3 146 PHE 146 146 146 PHE PHE C . n 
C 3 147 MET 147 147 147 MET MET C . n 
C 3 148 ASN 148 148 148 ASN ASN C . n 
C 3 149 LEU 149 149 149 LEU LEU C . n 
C 3 150 ARG 150 150 150 ARG ARG C . n 
C 3 151 LEU 151 151 151 LEU LEU C . n 
C 3 152 ARG 152 152 152 ARG ARG C . n 
C 3 153 GLY 153 153 153 GLY GLY C . n 
C 3 154 GLY 154 154 154 GLY GLY C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        AMP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   AMP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         D 
_pdbx_nonpoly_scheme.entity_id       4 
_pdbx_nonpoly_scheme.mon_id          AMP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     201 
_pdbx_nonpoly_scheme.auth_seq_num    1 
_pdbx_nonpoly_scheme.pdb_mon_id      AMP 
_pdbx_nonpoly_scheme.auth_mon_id     AMP 
_pdbx_nonpoly_scheme.pdb_strand_id   C 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JTC 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9JTC 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 9374  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.528  ? 12735 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 13.040 ? 3471  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039  ? 1415  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1665  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9JTC 
_struct.title                        'Cryo-EM structure of bovine UBA7-UBE2L6-ISG15' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JTC 
_struct_keywords.text            'cryo-EM, UBA7, UBE2L6, ISG15, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP Q5GF34_BOVIN Q5GF34 ? 1 
;MDTLETSKLLDKELYSRQLYVLGLPAMQRIQGAKVLLSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSE
QDLGRSRAEASQKLLAELNGAVQVSVYTGDITKDLLLDFQVVVLTASRLEEQLRVGTLCHEHGVCFLVADTRGLVGQLFC
DFGENFTVQDPTEAEPLTANIQHISQGSPGILTLREEAGTHHFHTGDWVTFSGIEGMVELNGCDPRPLHVREDGTLEIGD
TTAFSCYLRGGAVTEVKRAKTVSHEPLDTALLQPRVVAQSAQKVRARCLHQSFRALHKFQQLHGRPPKPWDPVDAEMVVD
LAQAMGPLKGTEGEPLEEQLDEALVRTVALSSAGGLSPMAAVLGAVAAQEVLKAISGKFMPLDQWLYFDALDCLPEDGDP
FPNPEDCAPRRCRYDGQTAVFGTNFQEKLSHQHYLLVGAGAVGCELLKSFALMGLGAGDGGGVTVADMDHVELSNLSRQF
LFRSQDIHRKKAEVAAEATRRLNADLQVTPLNLQLDPTTEDIFGDDFFSGVNGVAAALDTFEARDYVAARCTHFLKPLLE
AGTMGTRGSASVFIPHVTENYKAPSDAASEDAPDPVCTVRYIPATTEHTVQWAKGEFDDLFCESAKTINSHPQALSSPED
LVKSQKQPLLQTMRGVLTERPQTWQDCVLWAFGHWQLRFHYGITQLLRTYPPDKVQEDGTPFWSGPKQCPQPLKFDASQD
MHLLYVLAAANLYAQMHGLPGSQDQTALRGLLNLLPLPDPQNLDRIFASELELDSPSGCKQLHEDLKTWSKGPPLKPLTF
EKDNDSNFHVDFVVAAASLRAQNYGIPVASHAETKRIVGRIIPAVVTTTAAVAGLVGLELYKVVGGPRPRHAFRHSYLHL
AENYFSRWVPKAPDIQKFHHLKWTCWDRLEVPAGQPERTLESLLAHIQELQGLRVTMLLHGSALLYSAGWSEEKQTQHLS
RRVTDLVKKVPGQRVLVLELGYEGEEDDTNFPRLHYKL
;
1 
2 UNP UB2L6_BOVIN  A5PJC4 ? 2 
;MTASKRVAKELEDLQKELPKYLRNLCSEEDNVLVWHALLLPERPPYNLKAFRLCISFPREYPFQPPTVKFTTRIYHPNVD
RDGRVCLPIISKKNWKASTRTCQVLEALNMLVNQPEPGQPVRLELAEQLTQDPELFDQMAQEFTLQFGVDRPS
;
1 
3 UNP ISG15_BOVIN  O02741 ? 3 
;MGGDLTVKMLGGQEILVPLRDSMTVSELKQFIAQKINVPAFQQRLAHLDSREVLQEGVPLVLQGLRAGSTVLLVVQNCIS
ILVRNDKGRSSPYEVQLKQTVAELKQQVCQKERVQADQFWLSFEGRPMDDEHPLEEYGLMKGCTVFMNLRLRGG
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JTC A 1 ? 998 ? Q5GF34 1 ? 998 ? 1 998 
2 2 9JTC B 1 ? 153 ? A5PJC4 1 ? 153 ? 1 153 
3 3 9JTC C 1 ? 154 ? O02741 1 ? 154 ? 1 154 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 9JTC ALA B 2   ? UNP A5PJC4 THR 2   conflict         2   1  
2 9JTC SER B 26  ? UNP A5PJC4 CYS 26  conflict         26  2  
2 9JTC SER B 54  ? UNP A5PJC4 CYS 54  conflict         54  3  
2 9JTC SER B 102 ? UNP A5PJC4 CYS 102 conflict         102 4  
2 9JTC HIS B 154 ? UNP A5PJC4 ?   ?   'expression tag' 154 5  
2 9JTC HIS B 155 ? UNP A5PJC4 ?   ?   'expression tag' 155 6  
2 9JTC HIS B 156 ? UNP A5PJC4 ?   ?   'expression tag' 156 7  
2 9JTC HIS B 157 ? UNP A5PJC4 ?   ?   'expression tag' 157 8  
2 9JTC HIS B 158 ? UNP A5PJC4 ?   ?   'expression tag' 158 9  
2 9JTC HIS B 159 ? UNP A5PJC4 ?   ?   'expression tag' 159 10 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ARG A 29  ? GLY A 32  ? ARG A 29  GLY A 32  5 ? 4  
HELX_P HELX_P2  AA2 GLN A 41  ? GLY A 55  ? GLN A 41  GLY A 55  1 ? 15 
HELX_P HELX_P3  AA3 CYS A 68  ? LEU A 72  ? CYS A 68  LEU A 72  5 ? 5  
HELX_P HELX_P4  AA4 SER A 79  ? LEU A 83  ? SER A 79  LEU A 83  5 ? 5  
HELX_P HELX_P5  AA5 SER A 86  ? ASN A 99  ? SER A 86  ASN A 99  1 ? 14 
HELX_P HELX_P6  AA6 THR A 112 ? LEU A 117 ? THR A 112 LEU A 117 1 ? 6  
HELX_P HELX_P7  AA7 ARG A 128 ? HIS A 142 ? ARG A 128 HIS A 142 1 ? 15 
HELX_P HELX_P8  AA8 MET A 217 ? ASN A 221 ? MET A 217 ASN A 221 5 ? 5  
HELX_P HELX_P9  AA9 PRO A 266 ? LEU A 271 ? PRO A 266 LEU A 271 1 ? 6  
HELX_P HELX_P10 AB1 GLN A 282 ? GLY A 304 ? GLN A 282 GLY A 304 1 ? 23 
HELX_P HELX_P11 AB2 ASP A 311 ? MET A 325 ? ASP A 311 MET A 325 1 ? 15 
HELX_P HELX_P12 AB3 ASP A 341 ? SER A 352 ? ASP A 341 SER A 352 1 ? 12 
HELX_P HELX_P13 AB4 LEU A 356 ? GLY A 377 ? LEU A 356 GLY A 377 1 ? 22 
HELX_P HELX_P14 AB5 LEU A 391 ? LEU A 394 ? LEU A 391 LEU A 394 5 ? 4  
HELX_P HELX_P15 AB6 TYR A 414 ? GLY A 422 ? TYR A 414 GLY A 422 1 ? 9  
HELX_P HELX_P16 AB7 GLY A 422 ? HIS A 431 ? GLY A 422 HIS A 431 1 ? 10 
HELX_P HELX_P17 AB8 GLY A 440 ? GLY A 454 ? GLY A 440 GLY A 454 1 ? 15 
HELX_P HELX_P18 AB9 GLU A 472 ? LEU A 476 ? GLU A 472 LEU A 476 5 ? 5  
HELX_P HELX_P19 AC1 ARG A 483 ? ILE A 487 ? ARG A 483 ILE A 487 5 ? 5  
HELX_P HELX_P20 AC2 LYS A 490 ? ASN A 503 ? LYS A 490 ASN A 503 1 ? 14 
HELX_P HELX_P21 AC3 ASP A 516 ? GLU A 520 ? ASP A 516 GLU A 520 5 ? 5  
HELX_P HELX_P22 AC4 GLY A 524 ? VAL A 531 ? GLY A 524 VAL A 531 1 ? 8  
HELX_P HELX_P23 AC5 THR A 540 ? LEU A 555 ? THR A 540 LEU A 555 1 ? 16 
HELX_P HELX_P24 AC6 PRO A 595 ? ARG A 600 ? PRO A 595 ARG A 600 1 ? 6  
HELX_P HELX_P25 AC7 THR A 605 ? CYS A 622 ? THR A 605 CYS A 622 1 ? 18 
HELX_P HELX_P26 AC8 CYS A 622 ? HIS A 631 ? CYS A 622 HIS A 631 1 ? 10 
HELX_P HELX_P27 AC9 PRO A 632 ? SER A 636 ? PRO A 632 SER A 636 5 ? 5  
HELX_P HELX_P28 AD1 SER A 637 ? GLN A 645 ? SER A 637 GLN A 645 1 ? 9  
HELX_P HELX_P29 AD2 LYS A 646 ? GLY A 655 ? LYS A 646 GLY A 655 1 ? 10 
HELX_P HELX_P30 AD3 THR A 663 ? HIS A 680 ? THR A 663 HIS A 680 1 ? 18 
HELX_P HELX_P31 AD4 HIS A 680 ? TYR A 690 ? HIS A 680 TYR A 690 1 ? 11 
HELX_P HELX_P32 AD5 GLN A 719 ? GLY A 738 ? GLN A 719 GLY A 738 1 ? 20 
HELX_P HELX_P33 AD6 ASP A 744 ? LEU A 755 ? ASP A 744 LEU A 755 1 ? 12 
HELX_P HELX_P34 AD7 PRO A 760 ? ILE A 766 ? PRO A 760 ILE A 766 5 ? 7  
HELX_P HELX_P35 AD8 SER A 769 ? ASP A 774 ? SER A 769 ASP A 774 1 ? 6  
HELX_P HELX_P36 AD9 SER A 775 ? LYS A 787 ? SER A 775 LYS A 787 1 ? 13 
HELX_P HELX_P37 AE1 PHE A 808 ? GLY A 825 ? PHE A 808 GLY A 825 1 ? 18 
HELX_P HELX_P38 AE2 SER A 830 ? ARG A 840 ? SER A 830 ARG A 840 1 ? 11 
HELX_P HELX_P39 AE3 VAL A 845 ? GLY A 865 ? VAL A 845 GLY A 865 1 ? 21 
HELX_P HELX_P40 AE4 ALA A 881 ? ASN A 883 ? ALA A 881 ASN A 883 5 ? 3  
HELX_P HELX_P41 AE5 THR A 919 ? GLY A 932 ? THR A 919 GLY A 932 1 ? 14 
HELX_P HELX_P42 AE6 SER A 951 ? ARG A 961 ? SER A 951 ARG A 961 1 ? 11 
HELX_P HELX_P43 AE7 SER B 4   ? LYS B 16  ? SER B 4   LYS B 16  1 ? 13 
HELX_P HELX_P44 AE8 PRO B 45  ? LYS B 49  ? PRO B 45  LYS B 49  5 ? 5  
HELX_P HELX_P45 AE9 ARG B 100 ? GLN B 114 ? ARG B 100 GLN B 114 1 ? 15 
HELX_P HELX_P46 AF1 ARG B 122 ? ASP B 132 ? ARG B 122 ASP B 132 1 ? 11 
HELX_P HELX_P47 AF2 ASP B 132 ? PHE B 147 ? ASP B 132 PHE B 147 1 ? 16 
HELX_P HELX_P48 AF3 THR C 100 ? ARG C 113 ? THR C 100 ARG C 113 1 ? 14 
HELX_P HELX_P49 AF4 GLN C 115 ? ASP C 117 ? GLN C 115 ASP C 117 5 ? 3  
HELX_P HELX_P50 AF5 LEU C 134 ? GLY C 138 ? LEU C 134 GLY C 138 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            597 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            86 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             597 
_struct_conn.ptnr2_auth_asym_id            B 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             86 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.024 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       597 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     B 
_pdbx_modification_feature.modified_residue_label_seq_id      86 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        597 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      B 
_pdbx_modification_feature.modified_residue_auth_seq_id       86 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 2 ? 
AA3 ? 7 ? 
AA4 ? 8 ? 
AA5 ? 2 ? 
AA6 ? 5 ? 
AA7 ? 4 ? 
AA8 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA4 7 8 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? parallel      
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 103 ? VAL A 106 ? GLN A 103 VAL A 106 
AA1 2 SER A 58  ? HIS A 62  ? SER A 58  HIS A 62  
AA1 3 LYS A 34  ? SER A 38  ? LYS A 34  SER A 38  
AA1 4 VAL A 121 ? LEU A 124 ? VAL A 121 LEU A 124 
AA1 5 CYS A 145 ? ARG A 152 ? CYS A 145 ARG A 152 
AA1 6 VAL A 155 ? ASP A 161 ? VAL A 155 ASP A 161 
AA1 7 TRP A 385 ? ASP A 389 ? TRP A 385 ASP A 389 
AA2 1 PHE A 166 ? VAL A 168 ? PHE A 166 VAL A 168 
AA2 2 LYS A 260 ? VAL A 262 ? LYS A 260 VAL A 262 
AA3 1 ARG A 226 ? PRO A 227 ? ARG A 226 PRO A 227 
AA3 2 TRP A 208 ? ILE A 214 ? TRP A 208 ILE A 214 
AA3 3 GLY A 250 ? GLU A 255 ? GLY A 250 GLU A 255 
AA3 4 ALA A 179 ? ILE A 184 ? ALA A 179 ILE A 184 
AA3 5 ILE A 191 ? LEU A 194 ? ILE A 191 LEU A 194 
AA3 6 LEU A 236 ? GLU A 237 ? LEU A 236 GLU A 237 
AA3 7 HIS A 229 ? VAL A 230 ? HIS A 229 VAL A 230 
AA4 1 VAL A 508 ? LEU A 511 ? VAL A 508 LEU A 511 
AA4 2 GLY A 462 ? ALA A 466 ? GLY A 462 ALA A 466 
AA4 3 HIS A 433 ? VAL A 437 ? HIS A 433 VAL A 437 
AA4 4 GLY A 533 ? ALA A 536 ? GLY A 533 ALA A 536 
AA4 5 LEU A 558 ? MET A 564 ? LEU A 558 MET A 564 
AA4 6 ARG A 567 ? PHE A 573 ? ARG A 567 PHE A 573 
AA4 7 HIS A 875 ? HIS A 879 ? HIS A 875 HIS A 879 
AA4 8 TYR A 884 ? TRP A 888 ? TYR A 884 TRP A 888 
AA5 1 GLN A 896 ? PHE A 898 ? GLN A 896 PHE A 898 
AA5 2 LEU A 901 ? TRP A 903 ? LEU A 901 TRP A 903 
AA6 1 ARG A 908 ? PRO A 912 ? ARG A 908 PRO A 912 
AA6 2 ARG A 993 ? LYS A 997 ? ARG A 993 LYS A 997 
AA6 3 VAL A 975 ? TYR A 982 ? VAL A 975 TYR A 982 
AA6 4 VAL A 935 ? HIS A 940 ? VAL A 935 HIS A 940 
AA6 5 ALA A 943 ? SER A 947 ? ALA A 943 SER A 947 
AA7 1 LEU B 22  ? SER B 27  ? LEU B 22  SER B 27  
AA7 2 VAL B 34  ? LEU B 39  ? VAL B 34  LEU B 39  
AA7 3 PHE B 51  ? SER B 56  ? PHE B 51  SER B 56  
AA7 4 THR B 67  ? PHE B 70  ? THR B 67  PHE B 70  
AA8 1 SER C 90  ? TYR C 93  ? SER C 90  TYR C 93  
AA8 2 ILE C 81  ? ARG C 84  ? ILE C 81  ARG C 84  
AA8 3 THR C 144 ? LEU C 149 ? THR C 144 LEU C 149 
AA8 4 PHE C 119 ? PHE C 123 ? PHE C 119 PHE C 123 
AA8 5 ARG C 126 ? MET C 128 ? ARG C 126 MET C 128 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O SER A 105 ? O SER A 105 N LEU A 61  ? N LEU A 61  
AA1 2 3 O THR A 60  ? O THR A 60  N LEU A 37  ? N LEU A 37  
AA1 3 4 N SER A 38  ? N SER A 38  O VAL A 123 ? O VAL A 123 
AA1 4 5 N LEU A 124 ? N LEU A 124 O LEU A 147 ? O LEU A 147 
AA1 5 6 N ASP A 150 ? N ASP A 150 O GLN A 157 ? O GLN A 157 
AA1 6 7 N GLY A 156 ? N GLY A 156 O PHE A 388 ? O PHE A 388 
AA2 1 2 N VAL A 168 ? N VAL A 168 O LYS A 260 ? O LYS A 260 
AA3 1 2 O ARG A 226 ? O ARG A 226 N VAL A 209 ? N VAL A 209 
AA3 2 3 N THR A 210 ? N THR A 210 O THR A 254 ? O THR A 254 
AA3 3 4 O VAL A 253 ? O VAL A 253 N ALA A 179 ? N ALA A 179 
AA3 4 5 N GLN A 182 ? N GLN A 182 O THR A 193 ? O THR A 193 
AA3 5 6 N LEU A 192 ? N LEU A 192 O LEU A 236 ? O LEU A 236 
AA3 6 7 O GLU A 237 ? O GLU A 237 N HIS A 229 ? N HIS A 229 
AA4 1 2 O THR A 509 ? O THR A 509 N VAL A 463 ? N VAL A 463 
AA4 2 3 O THR A 464 ? O THR A 464 N LEU A 436 ? N LEU A 436 
AA4 3 4 N VAL A 437 ? N VAL A 437 O ALA A 535 ? O ALA A 535 
AA4 4 5 N ALA A 536 ? N ALA A 536 O LEU A 559 ? O LEU A 559 
AA4 5 6 N LEU A 558 ? N LEU A 558 O PHE A 573 ? O PHE A 573 
AA4 6 7 N GLY A 568 ? N GLY A 568 O LEU A 878 ? O LEU A 878 
AA4 7 8 N HIS A 875 ? N HIS A 875 O TRP A 888 ? O TRP A 888 
AA5 1 2 N GLN A 896 ? N GLN A 896 O TRP A 903 ? O TRP A 903 
AA6 1 2 N LEU A 909 ? N LEU A 909 O HIS A 995 ? O HIS A 995 
AA6 2 3 O TYR A 996 ? O TYR A 996 N LEU A 976 ? N LEU A 976 
AA6 3 4 O GLU A 979 ? O GLU A 979 N LEU A 939 ? N LEU A 939 
AA6 4 5 N LEU A 938 ? N LEU A 938 O TYR A 946 ? O TYR A 946 
AA7 1 2 N SER B 26  ? N SER B 26  O HIS B 36  ? O HIS B 36  
AA7 2 3 N LEU B 39  ? N LEU B 39  O PHE B 51  ? O PHE B 51  
AA7 3 4 N SER B 56  ? N SER B 56  O THR B 67  ? O THR B 67  
AA8 1 2 O SER C 91  ? O SER C 91  N VAL C 83  ? N VAL C 83  
AA8 2 3 N ARG C 84  ? N ARG C 84  O VAL C 145 ? O VAL C 145 
AA8 3 4 O ASN C 148 ? O ASN C 148 N TRP C 120 ? N TRP C 120 
AA8 4 5 N PHE C 123 ? N PHE C 123 O ARG C 126 ? O ARG C 126 
# 
_pdbx_entry_details.entry_id                   9JTC 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 C C GLY 154 ? ? O3P C AMP 201 ? ? 1.37 
2 1 O C GLY 154 ? ? O3P C AMP 201 ? ? 1.38 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 63  ? ? -155.31 83.05   
2  1 LEU A 248 ? ? -100.38 -60.37  
3  1 PHE A 379 ? ? 59.97   174.25  
4  1 GLN A 384 ? ? -134.60 -38.26  
5  1 SER A 477 ? ? 69.50   -4.75   
6  1 HIS A 488 ? ? 59.07   9.12    
7  1 VAL A 577 ? ? -126.79 -50.46  
8  1 ILE A 602 ? ? -156.04 83.44   
9  1 HIS A 899 ? ? 56.46   -113.17 
10 1 GLU B 29  ? ? 70.38   -10.33  
11 1 GLU B 60  ? ? -95.29  30.76   
12 1 VAL B 121 ? ? -125.23 -50.93  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JTC 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9JTC 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.99 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               176617 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.6 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex structure of bovine UBA7-UBE2L6-ISG15' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        9JTC 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9JTC 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9JTC 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ASP 2   ? A ASP 2   
3   1 Y 1 A THR 3   ? A THR 3   
4   1 Y 1 A LEU 4   ? A LEU 4   
5   1 Y 1 A GLU 5   ? A GLU 5   
6   1 Y 1 A THR 6   ? A THR 6   
7   1 Y 1 A SER 7   ? A SER 7   
8   1 Y 1 A LYS 8   ? A LYS 8   
9   1 Y 1 A LEU 9   ? A LEU 9   
10  1 Y 1 A LEU 10  ? A LEU 10  
11  1 Y 1 A ASP 11  ? A ASP 11  
12  1 Y 1 A LYS 12  ? A LYS 12  
13  1 Y 1 A GLU 13  ? A GLU 13  
14  1 Y 1 A LEU 14  ? A LEU 14  
15  1 Y 1 A TYR 15  ? A TYR 15  
16  1 Y 1 A SER 16  ? A SER 16  
17  1 Y 1 A ARG 17  ? A ARG 17  
18  1 Y 1 A GLN 18  ? A GLN 18  
19  1 Y 1 A LEU 19  ? A LEU 19  
20  1 Y 1 A TYR 20  ? A TYR 20  
21  1 Y 1 A VAL 21  ? A VAL 21  
22  1 Y 1 A LEU 22  ? A LEU 22  
23  1 Y 1 A GLY 23  ? A GLY 23  
24  1 Y 1 A LEU 24  ? A LEU 24  
25  1 Y 1 A PRO 25  ? A PRO 25  
26  1 Y 1 A ALA 26  ? A ALA 26  
27  1 Y 1 A MET 27  ? A MET 27  
28  1 Y 1 A GLN 28  ? A GLN 28  
29  1 Y 1 A GLU 196 ? A GLU 196 
30  1 Y 1 A GLU 197 ? A GLU 197 
31  1 Y 1 A ALA 198 ? A ALA 198 
32  1 Y 1 A GLY 199 ? A GLY 199 
33  1 Y 1 A THR 200 ? A THR 200 
34  1 Y 1 A GLY 330 ? A GLY 330 
35  1 Y 1 A THR 331 ? A THR 331 
36  1 Y 1 A GLU 332 ? A GLU 332 
37  1 Y 1 A GLY 333 ? A GLY 333 
38  1 Y 1 A GLU 334 ? A GLU 334 
39  1 Y 1 A PRO 335 ? A PRO 335 
40  1 Y 1 A LEU 336 ? A LEU 336 
41  1 Y 1 A GLU 337 ? A GLU 337 
42  1 Y 1 A ASP 586 ? A ASP 586 
43  1 Y 1 A ALA 587 ? A ALA 587 
44  1 Y 1 A ALA 588 ? A ALA 588 
45  1 Y 1 A SER 589 ? A SER 589 
46  1 Y 1 A GLU 590 ? A GLU 590 
47  1 Y 1 A ASP 591 ? A ASP 591 
48  1 Y 1 A ALA 592 ? A ALA 592 
49  1 Y 1 A PRO 593 ? A PRO 593 
50  1 Y 1 A GLN 696 ? A GLN 696 
51  1 Y 1 A GLU 697 ? A GLU 697 
52  1 Y 1 A ASP 698 ? A ASP 698 
53  1 Y 1 A GLY 699 ? A GLY 699 
54  1 Y 1 A THR 700 ? A THR 700 
55  1 Y 1 A GLU 801 ? A GLU 801 
56  1 Y 1 A LYS 802 ? A LYS 802 
57  1 Y 1 A ASP 803 ? A ASP 803 
58  1 Y 1 A ASN 804 ? A ASN 804 
59  1 Y 1 A ASP 805 ? A ASP 805 
60  1 Y 1 A SER 806 ? A SER 806 
61  1 Y 1 B MET 1   ? B MET 1   
62  1 Y 1 B ALA 2   ? B ALA 2   
63  1 Y 1 B SER 153 ? B SER 153 
64  1 Y 1 B HIS 154 ? B HIS 154 
65  1 Y 1 B HIS 155 ? B HIS 155 
66  1 Y 1 B HIS 156 ? B HIS 156 
67  1 Y 1 B HIS 157 ? B HIS 157 
68  1 Y 1 B HIS 158 ? B HIS 158 
69  1 Y 1 B HIS 159 ? B HIS 159 
70  1 Y 1 C MET 1   ? C MET 1   
71  1 Y 1 C GLY 2   ? C GLY 2   
72  1 Y 1 C GLY 3   ? C GLY 3   
73  1 Y 1 C ASP 4   ? C ASP 4   
74  1 Y 1 C LEU 5   ? C LEU 5   
75  1 Y 1 C THR 6   ? C THR 6   
76  1 Y 1 C VAL 7   ? C VAL 7   
77  1 Y 1 C LYS 8   ? C LYS 8   
78  1 Y 1 C MET 9   ? C MET 9   
79  1 Y 1 C LEU 10  ? C LEU 10  
80  1 Y 1 C GLY 11  ? C GLY 11  
81  1 Y 1 C GLY 12  ? C GLY 12  
82  1 Y 1 C GLN 13  ? C GLN 13  
83  1 Y 1 C GLU 14  ? C GLU 14  
84  1 Y 1 C ILE 15  ? C ILE 15  
85  1 Y 1 C LEU 16  ? C LEU 16  
86  1 Y 1 C VAL 17  ? C VAL 17  
87  1 Y 1 C PRO 18  ? C PRO 18  
88  1 Y 1 C LEU 19  ? C LEU 19  
89  1 Y 1 C ARG 20  ? C ARG 20  
90  1 Y 1 C ASP 21  ? C ASP 21  
91  1 Y 1 C SER 22  ? C SER 22  
92  1 Y 1 C MET 23  ? C MET 23  
93  1 Y 1 C THR 24  ? C THR 24  
94  1 Y 1 C VAL 25  ? C VAL 25  
95  1 Y 1 C SER 26  ? C SER 26  
96  1 Y 1 C GLU 27  ? C GLU 27  
97  1 Y 1 C LEU 28  ? C LEU 28  
98  1 Y 1 C LYS 29  ? C LYS 29  
99  1 Y 1 C GLN 30  ? C GLN 30  
100 1 Y 1 C PHE 31  ? C PHE 31  
101 1 Y 1 C ILE 32  ? C ILE 32  
102 1 Y 1 C ALA 33  ? C ALA 33  
103 1 Y 1 C GLN 34  ? C GLN 34  
104 1 Y 1 C LYS 35  ? C LYS 35  
105 1 Y 1 C ILE 36  ? C ILE 36  
106 1 Y 1 C ASN 37  ? C ASN 37  
107 1 Y 1 C VAL 38  ? C VAL 38  
108 1 Y 1 C PRO 39  ? C PRO 39  
109 1 Y 1 C ALA 40  ? C ALA 40  
110 1 Y 1 C PHE 41  ? C PHE 41  
111 1 Y 1 C GLN 42  ? C GLN 42  
112 1 Y 1 C GLN 43  ? C GLN 43  
113 1 Y 1 C ARG 44  ? C ARG 44  
114 1 Y 1 C LEU 45  ? C LEU 45  
115 1 Y 1 C ALA 46  ? C ALA 46  
116 1 Y 1 C HIS 47  ? C HIS 47  
117 1 Y 1 C LEU 48  ? C LEU 48  
118 1 Y 1 C ASP 49  ? C ASP 49  
119 1 Y 1 C SER 50  ? C SER 50  
120 1 Y 1 C ARG 51  ? C ARG 51  
121 1 Y 1 C GLU 52  ? C GLU 52  
122 1 Y 1 C VAL 53  ? C VAL 53  
123 1 Y 1 C LEU 54  ? C LEU 54  
124 1 Y 1 C GLN 55  ? C GLN 55  
125 1 Y 1 C GLU 56  ? C GLU 56  
126 1 Y 1 C GLY 57  ? C GLY 57  
127 1 Y 1 C VAL 58  ? C VAL 58  
128 1 Y 1 C PRO 59  ? C PRO 59  
129 1 Y 1 C LEU 60  ? C LEU 60  
130 1 Y 1 C VAL 61  ? C VAL 61  
131 1 Y 1 C LEU 62  ? C LEU 62  
132 1 Y 1 C GLN 63  ? C GLN 63  
133 1 Y 1 C GLY 64  ? C GLY 64  
134 1 Y 1 C LEU 65  ? C LEU 65  
135 1 Y 1 C ARG 66  ? C ARG 66  
136 1 Y 1 C ALA 67  ? C ALA 67  
137 1 Y 1 C GLY 68  ? C GLY 68  
138 1 Y 1 C SER 69  ? C SER 69  
139 1 Y 1 C THR 70  ? C THR 70  
140 1 Y 1 C VAL 71  ? C VAL 71  
141 1 Y 1 C LEU 72  ? C LEU 72  
142 1 Y 1 C LEU 73  ? C LEU 73  
143 1 Y 1 C VAL 74  ? C VAL 74  
144 1 Y 1 C VAL 75  ? C VAL 75  
145 1 Y 1 C GLN 76  ? C GLN 76  
146 1 Y 1 C ASN 77  ? C ASN 77  
147 1 Y 1 C CYS 78  ? C CYS 78  
148 1 Y 1 C ILE 79  ? C ILE 79  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
AMP P      P N N 14  
AMP O1P    O N N 15  
AMP O2P    O N N 16  
AMP O3P    O N N 17  
AMP "O5'"  O N N 18  
AMP "C5'"  C N N 19  
AMP "C4'"  C N R 20  
AMP "O4'"  O N N 21  
AMP "C3'"  C N S 22  
AMP "O3'"  O N N 23  
AMP "C2'"  C N R 24  
AMP "O2'"  O N N 25  
AMP "C1'"  C N R 26  
AMP N9     N Y N 27  
AMP C8     C Y N 28  
AMP N7     N Y N 29  
AMP C5     C Y N 30  
AMP C6     C Y N 31  
AMP N6     N N N 32  
AMP N1     N Y N 33  
AMP C2     C Y N 34  
AMP N3     N Y N 35  
AMP C4     C Y N 36  
AMP HOP2   H N N 37  
AMP HOP3   H N N 38  
AMP "H5'1" H N N 39  
AMP "H5'2" H N N 40  
AMP "H4'"  H N N 41  
AMP "H3'"  H N N 42  
AMP "HO3'" H N N 43  
AMP "H2'"  H N N 44  
AMP "HO2'" H N N 45  
AMP "H1'"  H N N 46  
AMP H8     H N N 47  
AMP HN61   H N N 48  
AMP HN62   H N N 49  
AMP H2     H N N 50  
ARG N      N N N 51  
ARG CA     C N S 52  
ARG C      C N N 53  
ARG O      O N N 54  
ARG CB     C N N 55  
ARG CG     C N N 56  
ARG CD     C N N 57  
ARG NE     N N N 58  
ARG CZ     C N N 59  
ARG NH1    N N N 60  
ARG NH2    N N N 61  
ARG OXT    O N N 62  
ARG H      H N N 63  
ARG H2     H N N 64  
ARG HA     H N N 65  
ARG HB2    H N N 66  
ARG HB3    H N N 67  
ARG HG2    H N N 68  
ARG HG3    H N N 69  
ARG HD2    H N N 70  
ARG HD3    H N N 71  
ARG HE     H N N 72  
ARG HH11   H N N 73  
ARG HH12   H N N 74  
ARG HH21   H N N 75  
ARG HH22   H N N 76  
ARG HXT    H N N 77  
ASN N      N N N 78  
ASN CA     C N S 79  
ASN C      C N N 80  
ASN O      O N N 81  
ASN CB     C N N 82  
ASN CG     C N N 83  
ASN OD1    O N N 84  
ASN ND2    N N N 85  
ASN OXT    O N N 86  
ASN H      H N N 87  
ASN H2     H N N 88  
ASN HA     H N N 89  
ASN HB2    H N N 90  
ASN HB3    H N N 91  
ASN HD21   H N N 92  
ASN HD22   H N N 93  
ASN HXT    H N N 94  
ASP N      N N N 95  
ASP CA     C N S 96  
ASP C      C N N 97  
ASP O      O N N 98  
ASP CB     C N N 99  
ASP CG     C N N 100 
ASP OD1    O N N 101 
ASP OD2    O N N 102 
ASP OXT    O N N 103 
ASP H      H N N 104 
ASP H2     H N N 105 
ASP HA     H N N 106 
ASP HB2    H N N 107 
ASP HB3    H N N 108 
ASP HD2    H N N 109 
ASP HXT    H N N 110 
CYS N      N N N 111 
CYS CA     C N R 112 
CYS C      C N N 113 
CYS O      O N N 114 
CYS CB     C N N 115 
CYS SG     S N N 116 
CYS OXT    O N N 117 
CYS H      H N N 118 
CYS H2     H N N 119 
CYS HA     H N N 120 
CYS HB2    H N N 121 
CYS HB3    H N N 122 
CYS HG     H N N 123 
CYS HXT    H N N 124 
GLN N      N N N 125 
GLN CA     C N S 126 
GLN C      C N N 127 
GLN O      O N N 128 
GLN CB     C N N 129 
GLN CG     C N N 130 
GLN CD     C N N 131 
GLN OE1    O N N 132 
GLN NE2    N N N 133 
GLN OXT    O N N 134 
GLN H      H N N 135 
GLN H2     H N N 136 
GLN HA     H N N 137 
GLN HB2    H N N 138 
GLN HB3    H N N 139 
GLN HG2    H N N 140 
GLN HG3    H N N 141 
GLN HE21   H N N 142 
GLN HE22   H N N 143 
GLN HXT    H N N 144 
GLU N      N N N 145 
GLU CA     C N S 146 
GLU C      C N N 147 
GLU O      O N N 148 
GLU CB     C N N 149 
GLU CG     C N N 150 
GLU CD     C N N 151 
GLU OE1    O N N 152 
GLU OE2    O N N 153 
GLU OXT    O N N 154 
GLU H      H N N 155 
GLU H2     H N N 156 
GLU HA     H N N 157 
GLU HB2    H N N 158 
GLU HB3    H N N 159 
GLU HG2    H N N 160 
GLU HG3    H N N 161 
GLU HE2    H N N 162 
GLU HXT    H N N 163 
GLY N      N N N 164 
GLY CA     C N N 165 
GLY C      C N N 166 
GLY O      O N N 167 
GLY OXT    O N N 168 
GLY H      H N N 169 
GLY H2     H N N 170 
GLY HA2    H N N 171 
GLY HA3    H N N 172 
GLY HXT    H N N 173 
HIS N      N N N 174 
HIS CA     C N S 175 
HIS C      C N N 176 
HIS O      O N N 177 
HIS CB     C N N 178 
HIS CG     C Y N 179 
HIS ND1    N Y N 180 
HIS CD2    C Y N 181 
HIS CE1    C Y N 182 
HIS NE2    N Y N 183 
HIS OXT    O N N 184 
HIS H      H N N 185 
HIS H2     H N N 186 
HIS HA     H N N 187 
HIS HB2    H N N 188 
HIS HB3    H N N 189 
HIS HD1    H N N 190 
HIS HD2    H N N 191 
HIS HE1    H N N 192 
HIS HE2    H N N 193 
HIS HXT    H N N 194 
ILE N      N N N 195 
ILE CA     C N S 196 
ILE C      C N N 197 
ILE O      O N N 198 
ILE CB     C N S 199 
ILE CG1    C N N 200 
ILE CG2    C N N 201 
ILE CD1    C N N 202 
ILE OXT    O N N 203 
ILE H      H N N 204 
ILE H2     H N N 205 
ILE HA     H N N 206 
ILE HB     H N N 207 
ILE HG12   H N N 208 
ILE HG13   H N N 209 
ILE HG21   H N N 210 
ILE HG22   H N N 211 
ILE HG23   H N N 212 
ILE HD11   H N N 213 
ILE HD12   H N N 214 
ILE HD13   H N N 215 
ILE HXT    H N N 216 
LEU N      N N N 217 
LEU CA     C N S 218 
LEU C      C N N 219 
LEU O      O N N 220 
LEU CB     C N N 221 
LEU CG     C N N 222 
LEU CD1    C N N 223 
LEU CD2    C N N 224 
LEU OXT    O N N 225 
LEU H      H N N 226 
LEU H2     H N N 227 
LEU HA     H N N 228 
LEU HB2    H N N 229 
LEU HB3    H N N 230 
LEU HG     H N N 231 
LEU HD11   H N N 232 
LEU HD12   H N N 233 
LEU HD13   H N N 234 
LEU HD21   H N N 235 
LEU HD22   H N N 236 
LEU HD23   H N N 237 
LEU HXT    H N N 238 
LYS N      N N N 239 
LYS CA     C N S 240 
LYS C      C N N 241 
LYS O      O N N 242 
LYS CB     C N N 243 
LYS CG     C N N 244 
LYS CD     C N N 245 
LYS CE     C N N 246 
LYS NZ     N N N 247 
LYS OXT    O N N 248 
LYS H      H N N 249 
LYS H2     H N N 250 
LYS HA     H N N 251 
LYS HB2    H N N 252 
LYS HB3    H N N 253 
LYS HG2    H N N 254 
LYS HG3    H N N 255 
LYS HD2    H N N 256 
LYS HD3    H N N 257 
LYS HE2    H N N 258 
LYS HE3    H N N 259 
LYS HZ1    H N N 260 
LYS HZ2    H N N 261 
LYS HZ3    H N N 262 
LYS HXT    H N N 263 
MET N      N N N 264 
MET CA     C N S 265 
MET C      C N N 266 
MET O      O N N 267 
MET CB     C N N 268 
MET CG     C N N 269 
MET SD     S N N 270 
MET CE     C N N 271 
MET OXT    O N N 272 
MET H      H N N 273 
MET H2     H N N 274 
MET HA     H N N 275 
MET HB2    H N N 276 
MET HB3    H N N 277 
MET HG2    H N N 278 
MET HG3    H N N 279 
MET HE1    H N N 280 
MET HE2    H N N 281 
MET HE3    H N N 282 
MET HXT    H N N 283 
PHE N      N N N 284 
PHE CA     C N S 285 
PHE C      C N N 286 
PHE O      O N N 287 
PHE CB     C N N 288 
PHE CG     C Y N 289 
PHE CD1    C Y N 290 
PHE CD2    C Y N 291 
PHE CE1    C Y N 292 
PHE CE2    C Y N 293 
PHE CZ     C Y N 294 
PHE OXT    O N N 295 
PHE H      H N N 296 
PHE H2     H N N 297 
PHE HA     H N N 298 
PHE HB2    H N N 299 
PHE HB3    H N N 300 
PHE HD1    H N N 301 
PHE HD2    H N N 302 
PHE HE1    H N N 303 
PHE HE2    H N N 304 
PHE HZ     H N N 305 
PHE HXT    H N N 306 
PRO N      N N N 307 
PRO CA     C N S 308 
PRO C      C N N 309 
PRO O      O N N 310 
PRO CB     C N N 311 
PRO CG     C N N 312 
PRO CD     C N N 313 
PRO OXT    O N N 314 
PRO H      H N N 315 
PRO HA     H N N 316 
PRO HB2    H N N 317 
PRO HB3    H N N 318 
PRO HG2    H N N 319 
PRO HG3    H N N 320 
PRO HD2    H N N 321 
PRO HD3    H N N 322 
PRO HXT    H N N 323 
SER N      N N N 324 
SER CA     C N S 325 
SER C      C N N 326 
SER O      O N N 327 
SER CB     C N N 328 
SER OG     O N N 329 
SER OXT    O N N 330 
SER H      H N N 331 
SER H2     H N N 332 
SER HA     H N N 333 
SER HB2    H N N 334 
SER HB3    H N N 335 
SER HG     H N N 336 
SER HXT    H N N 337 
THR N      N N N 338 
THR CA     C N S 339 
THR C      C N N 340 
THR O      O N N 341 
THR CB     C N R 342 
THR OG1    O N N 343 
THR CG2    C N N 344 
THR OXT    O N N 345 
THR H      H N N 346 
THR H2     H N N 347 
THR HA     H N N 348 
THR HB     H N N 349 
THR HG1    H N N 350 
THR HG21   H N N 351 
THR HG22   H N N 352 
THR HG23   H N N 353 
THR HXT    H N N 354 
TRP N      N N N 355 
TRP CA     C N S 356 
TRP C      C N N 357 
TRP O      O N N 358 
TRP CB     C N N 359 
TRP CG     C Y N 360 
TRP CD1    C Y N 361 
TRP CD2    C Y N 362 
TRP NE1    N Y N 363 
TRP CE2    C Y N 364 
TRP CE3    C Y N 365 
TRP CZ2    C Y N 366 
TRP CZ3    C Y N 367 
TRP CH2    C Y N 368 
TRP OXT    O N N 369 
TRP H      H N N 370 
TRP H2     H N N 371 
TRP HA     H N N 372 
TRP HB2    H N N 373 
TRP HB3    H N N 374 
TRP HD1    H N N 375 
TRP HE1    H N N 376 
TRP HE3    H N N 377 
TRP HZ2    H N N 378 
TRP HZ3    H N N 379 
TRP HH2    H N N 380 
TRP HXT    H N N 381 
TYR N      N N N 382 
TYR CA     C N S 383 
TYR C      C N N 384 
TYR O      O N N 385 
TYR CB     C N N 386 
TYR CG     C Y N 387 
TYR CD1    C Y N 388 
TYR CD2    C Y N 389 
TYR CE1    C Y N 390 
TYR CE2    C Y N 391 
TYR CZ     C Y N 392 
TYR OH     O N N 393 
TYR OXT    O N N 394 
TYR H      H N N 395 
TYR H2     H N N 396 
TYR HA     H N N 397 
TYR HB2    H N N 398 
TYR HB3    H N N 399 
TYR HD1    H N N 400 
TYR HD2    H N N 401 
TYR HE1    H N N 402 
TYR HE2    H N N 403 
TYR HH     H N N 404 
TYR HXT    H N N 405 
VAL N      N N N 406 
VAL CA     C N S 407 
VAL C      C N N 408 
VAL O      O N N 409 
VAL CB     C N N 410 
VAL CG1    C N N 411 
VAL CG2    C N N 412 
VAL OXT    O N N 413 
VAL H      H N N 414 
VAL H2     H N N 415 
VAL HA     H N N 416 
VAL HB     H N N 417 
VAL HG11   H N N 418 
VAL HG12   H N N 419 
VAL HG13   H N N 420 
VAL HG21   H N N 421 
VAL HG22   H N N 422 
VAL HG23   H N N 423 
VAL HXT    H N N 424 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
AMP P     O1P    doub N N 13  
AMP P     O2P    sing N N 14  
AMP P     O3P    sing N N 15  
AMP P     "O5'"  sing N N 16  
AMP O2P   HOP2   sing N N 17  
AMP O3P   HOP3   sing N N 18  
AMP "O5'" "C5'"  sing N N 19  
AMP "C5'" "C4'"  sing N N 20  
AMP "C5'" "H5'1" sing N N 21  
AMP "C5'" "H5'2" sing N N 22  
AMP "C4'" "O4'"  sing N N 23  
AMP "C4'" "C3'"  sing N N 24  
AMP "C4'" "H4'"  sing N N 25  
AMP "O4'" "C1'"  sing N N 26  
AMP "C3'" "O3'"  sing N N 27  
AMP "C3'" "C2'"  sing N N 28  
AMP "C3'" "H3'"  sing N N 29  
AMP "O3'" "HO3'" sing N N 30  
AMP "C2'" "O2'"  sing N N 31  
AMP "C2'" "C1'"  sing N N 32  
AMP "C2'" "H2'"  sing N N 33  
AMP "O2'" "HO2'" sing N N 34  
AMP "C1'" N9     sing N N 35  
AMP "C1'" "H1'"  sing N N 36  
AMP N9    C8     sing Y N 37  
AMP N9    C4     sing Y N 38  
AMP C8    N7     doub Y N 39  
AMP C8    H8     sing N N 40  
AMP N7    C5     sing Y N 41  
AMP C5    C6     sing Y N 42  
AMP C5    C4     doub Y N 43  
AMP C6    N6     sing N N 44  
AMP C6    N1     doub Y N 45  
AMP N6    HN61   sing N N 46  
AMP N6    HN62   sing N N 47  
AMP N1    C2     sing Y N 48  
AMP C2    N3     doub Y N 49  
AMP C2    H2     sing N N 50  
AMP N3    C4     sing Y N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
CYS N     CA     sing N N 109 
CYS N     H      sing N N 110 
CYS N     H2     sing N N 111 
CYS CA    C      sing N N 112 
CYS CA    CB     sing N N 113 
CYS CA    HA     sing N N 114 
CYS C     O      doub N N 115 
CYS C     OXT    sing N N 116 
CYS CB    SG     sing N N 117 
CYS CB    HB2    sing N N 118 
CYS CB    HB3    sing N N 119 
CYS SG    HG     sing N N 120 
CYS OXT   HXT    sing N N 121 
GLN N     CA     sing N N 122 
GLN N     H      sing N N 123 
GLN N     H2     sing N N 124 
GLN CA    C      sing N N 125 
GLN CA    CB     sing N N 126 
GLN CA    HA     sing N N 127 
GLN C     O      doub N N 128 
GLN C     OXT    sing N N 129 
GLN CB    CG     sing N N 130 
GLN CB    HB2    sing N N 131 
GLN CB    HB3    sing N N 132 
GLN CG    CD     sing N N 133 
GLN CG    HG2    sing N N 134 
GLN CG    HG3    sing N N 135 
GLN CD    OE1    doub N N 136 
GLN CD    NE2    sing N N 137 
GLN NE2   HE21   sing N N 138 
GLN NE2   HE22   sing N N 139 
GLN OXT   HXT    sing N N 140 
GLU N     CA     sing N N 141 
GLU N     H      sing N N 142 
GLU N     H2     sing N N 143 
GLU CA    C      sing N N 144 
GLU CA    CB     sing N N 145 
GLU CA    HA     sing N N 146 
GLU C     O      doub N N 147 
GLU C     OXT    sing N N 148 
GLU CB    CG     sing N N 149 
GLU CB    HB2    sing N N 150 
GLU CB    HB3    sing N N 151 
GLU CG    CD     sing N N 152 
GLU CG    HG2    sing N N 153 
GLU CG    HG3    sing N N 154 
GLU CD    OE1    doub N N 155 
GLU CD    OE2    sing N N 156 
GLU OE2   HE2    sing N N 157 
GLU OXT   HXT    sing N N 158 
GLY N     CA     sing N N 159 
GLY N     H      sing N N 160 
GLY N     H2     sing N N 161 
GLY CA    C      sing N N 162 
GLY CA    HA2    sing N N 163 
GLY CA    HA3    sing N N 164 
GLY C     O      doub N N 165 
GLY C     OXT    sing N N 166 
GLY OXT   HXT    sing N N 167 
HIS N     CA     sing N N 168 
HIS N     H      sing N N 169 
HIS N     H2     sing N N 170 
HIS CA    C      sing N N 171 
HIS CA    CB     sing N N 172 
HIS CA    HA     sing N N 173 
HIS C     O      doub N N 174 
HIS C     OXT    sing N N 175 
HIS CB    CG     sing N N 176 
HIS CB    HB2    sing N N 177 
HIS CB    HB3    sing N N 178 
HIS CG    ND1    sing Y N 179 
HIS CG    CD2    doub Y N 180 
HIS ND1   CE1    doub Y N 181 
HIS ND1   HD1    sing N N 182 
HIS CD2   NE2    sing Y N 183 
HIS CD2   HD2    sing N N 184 
HIS CE1   NE2    sing Y N 185 
HIS CE1   HE1    sing N N 186 
HIS NE2   HE2    sing N N 187 
HIS OXT   HXT    sing N N 188 
ILE N     CA     sing N N 189 
ILE N     H      sing N N 190 
ILE N     H2     sing N N 191 
ILE CA    C      sing N N 192 
ILE CA    CB     sing N N 193 
ILE CA    HA     sing N N 194 
ILE C     O      doub N N 195 
ILE C     OXT    sing N N 196 
ILE CB    CG1    sing N N 197 
ILE CB    CG2    sing N N 198 
ILE CB    HB     sing N N 199 
ILE CG1   CD1    sing N N 200 
ILE CG1   HG12   sing N N 201 
ILE CG1   HG13   sing N N 202 
ILE CG2   HG21   sing N N 203 
ILE CG2   HG22   sing N N 204 
ILE CG2   HG23   sing N N 205 
ILE CD1   HD11   sing N N 206 
ILE CD1   HD12   sing N N 207 
ILE CD1   HD13   sing N N 208 
ILE OXT   HXT    sing N N 209 
LEU N     CA     sing N N 210 
LEU N     H      sing N N 211 
LEU N     H2     sing N N 212 
LEU CA    C      sing N N 213 
LEU CA    CB     sing N N 214 
LEU CA    HA     sing N N 215 
LEU C     O      doub N N 216 
LEU C     OXT    sing N N 217 
LEU CB    CG     sing N N 218 
LEU CB    HB2    sing N N 219 
LEU CB    HB3    sing N N 220 
LEU CG    CD1    sing N N 221 
LEU CG    CD2    sing N N 222 
LEU CG    HG     sing N N 223 
LEU CD1   HD11   sing N N 224 
LEU CD1   HD12   sing N N 225 
LEU CD1   HD13   sing N N 226 
LEU CD2   HD21   sing N N 227 
LEU CD2   HD22   sing N N 228 
LEU CD2   HD23   sing N N 229 
LEU OXT   HXT    sing N N 230 
LYS N     CA     sing N N 231 
LYS N     H      sing N N 232 
LYS N     H2     sing N N 233 
LYS CA    C      sing N N 234 
LYS CA    CB     sing N N 235 
LYS CA    HA     sing N N 236 
LYS C     O      doub N N 237 
LYS C     OXT    sing N N 238 
LYS CB    CG     sing N N 239 
LYS CB    HB2    sing N N 240 
LYS CB    HB3    sing N N 241 
LYS CG    CD     sing N N 242 
LYS CG    HG2    sing N N 243 
LYS CG    HG3    sing N N 244 
LYS CD    CE     sing N N 245 
LYS CD    HD2    sing N N 246 
LYS CD    HD3    sing N N 247 
LYS CE    NZ     sing N N 248 
LYS CE    HE2    sing N N 249 
LYS CE    HE3    sing N N 250 
LYS NZ    HZ1    sing N N 251 
LYS NZ    HZ2    sing N N 252 
LYS NZ    HZ3    sing N N 253 
LYS OXT   HXT    sing N N 254 
MET N     CA     sing N N 255 
MET N     H      sing N N 256 
MET N     H2     sing N N 257 
MET CA    C      sing N N 258 
MET CA    CB     sing N N 259 
MET CA    HA     sing N N 260 
MET C     O      doub N N 261 
MET C     OXT    sing N N 262 
MET CB    CG     sing N N 263 
MET CB    HB2    sing N N 264 
MET CB    HB3    sing N N 265 
MET CG    SD     sing N N 266 
MET CG    HG2    sing N N 267 
MET CG    HG3    sing N N 268 
MET SD    CE     sing N N 269 
MET CE    HE1    sing N N 270 
MET CE    HE2    sing N N 271 
MET CE    HE3    sing N N 272 
MET OXT   HXT    sing N N 273 
PHE N     CA     sing N N 274 
PHE N     H      sing N N 275 
PHE N     H2     sing N N 276 
PHE CA    C      sing N N 277 
PHE CA    CB     sing N N 278 
PHE CA    HA     sing N N 279 
PHE C     O      doub N N 280 
PHE C     OXT    sing N N 281 
PHE CB    CG     sing N N 282 
PHE CB    HB2    sing N N 283 
PHE CB    HB3    sing N N 284 
PHE CG    CD1    doub Y N 285 
PHE CG    CD2    sing Y N 286 
PHE CD1   CE1    sing Y N 287 
PHE CD1   HD1    sing N N 288 
PHE CD2   CE2    doub Y N 289 
PHE CD2   HD2    sing N N 290 
PHE CE1   CZ     doub Y N 291 
PHE CE1   HE1    sing N N 292 
PHE CE2   CZ     sing Y N 293 
PHE CE2   HE2    sing N N 294 
PHE CZ    HZ     sing N N 295 
PHE OXT   HXT    sing N N 296 
PRO N     CA     sing N N 297 
PRO N     CD     sing N N 298 
PRO N     H      sing N N 299 
PRO CA    C      sing N N 300 
PRO CA    CB     sing N N 301 
PRO CA    HA     sing N N 302 
PRO C     O      doub N N 303 
PRO C     OXT    sing N N 304 
PRO CB    CG     sing N N 305 
PRO CB    HB2    sing N N 306 
PRO CB    HB3    sing N N 307 
PRO CG    CD     sing N N 308 
PRO CG    HG2    sing N N 309 
PRO CG    HG3    sing N N 310 
PRO CD    HD2    sing N N 311 
PRO CD    HD3    sing N N 312 
PRO OXT   HXT    sing N N 313 
SER N     CA     sing N N 314 
SER N     H      sing N N 315 
SER N     H2     sing N N 316 
SER CA    C      sing N N 317 
SER CA    CB     sing N N 318 
SER CA    HA     sing N N 319 
SER C     O      doub N N 320 
SER C     OXT    sing N N 321 
SER CB    OG     sing N N 322 
SER CB    HB2    sing N N 323 
SER CB    HB3    sing N N 324 
SER OG    HG     sing N N 325 
SER OXT   HXT    sing N N 326 
THR N     CA     sing N N 327 
THR N     H      sing N N 328 
THR N     H2     sing N N 329 
THR CA    C      sing N N 330 
THR CA    CB     sing N N 331 
THR CA    HA     sing N N 332 
THR C     O      doub N N 333 
THR C     OXT    sing N N 334 
THR CB    OG1    sing N N 335 
THR CB    CG2    sing N N 336 
THR CB    HB     sing N N 337 
THR OG1   HG1    sing N N 338 
THR CG2   HG21   sing N N 339 
THR CG2   HG22   sing N N 340 
THR CG2   HG23   sing N N 341 
THR OXT   HXT    sing N N 342 
TRP N     CA     sing N N 343 
TRP N     H      sing N N 344 
TRP N     H2     sing N N 345 
TRP CA    C      sing N N 346 
TRP CA    CB     sing N N 347 
TRP CA    HA     sing N N 348 
TRP C     O      doub N N 349 
TRP C     OXT    sing N N 350 
TRP CB    CG     sing N N 351 
TRP CB    HB2    sing N N 352 
TRP CB    HB3    sing N N 353 
TRP CG    CD1    doub Y N 354 
TRP CG    CD2    sing Y N 355 
TRP CD1   NE1    sing Y N 356 
TRP CD1   HD1    sing N N 357 
TRP CD2   CE2    doub Y N 358 
TRP CD2   CE3    sing Y N 359 
TRP NE1   CE2    sing Y N 360 
TRP NE1   HE1    sing N N 361 
TRP CE2   CZ2    sing Y N 362 
TRP CE3   CZ3    doub Y N 363 
TRP CE3   HE3    sing N N 364 
TRP CZ2   CH2    doub Y N 365 
TRP CZ2   HZ2    sing N N 366 
TRP CZ3   CH2    sing Y N 367 
TRP CZ3   HZ3    sing N N 368 
TRP CH2   HH2    sing N N 369 
TRP OXT   HXT    sing N N 370 
TYR N     CA     sing N N 371 
TYR N     H      sing N N 372 
TYR N     H2     sing N N 373 
TYR CA    C      sing N N 374 
TYR CA    CB     sing N N 375 
TYR CA    HA     sing N N 376 
TYR C     O      doub N N 377 
TYR C     OXT    sing N N 378 
TYR CB    CG     sing N N 379 
TYR CB    HB2    sing N N 380 
TYR CB    HB3    sing N N 381 
TYR CG    CD1    doub Y N 382 
TYR CG    CD2    sing Y N 383 
TYR CD1   CE1    sing Y N 384 
TYR CD1   HD1    sing N N 385 
TYR CD2   CE2    doub Y N 386 
TYR CD2   HD2    sing N N 387 
TYR CE1   CZ     doub Y N 388 
TYR CE1   HE1    sing N N 389 
TYR CE2   CZ     sing Y N 390 
TYR CE2   HE2    sing N N 391 
TYR CZ    OH     sing N N 392 
TYR OH    HH     sing N N 393 
TYR OXT   HXT    sing N N 394 
VAL N     CA     sing N N 395 
VAL N     H      sing N N 396 
VAL N     H2     sing N N 397 
VAL CA    C      sing N N 398 
VAL CA    CB     sing N N 399 
VAL CA    HA     sing N N 400 
VAL C     O      doub N N 401 
VAL C     OXT    sing N N 402 
VAL CB    CG1    sing N N 403 
VAL CB    CG2    sing N N 404 
VAL CB    HB     sing N N 405 
VAL CG1   HG11   sing N N 406 
VAL CG1   HG12   sing N N 407 
VAL CG1   HG13   sing N N 408 
VAL CG2   HG21   sing N N 409 
VAL CG2   HG22   sing N N 410 
VAL CG2   HG23   sing N N 411 
VAL OXT   HXT    sing N N 412 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-10-03 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JTC 
_em_admin.last_update        2025-03-19 
_em_admin.map_release_date   2025-03-05 
_em_admin.title              'Cryo-EM structure of bovine UBA7-UBE2L6-ISG15' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9913 
_em_entity_assembly_naturalsource.organism             'Bos taurus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Academia Sinica (Taiwan)' 
_pdbx_audit_support.country                Taiwan 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9JTC 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N     . ARG A 1 29  ? 139.578 170.246 142.607 1.00 86.11  ? 29  ARG A N     1 
ATOM   2    C CA    . ARG A 1 29  ? 138.561 170.798 143.495 1.00 91.67  ? 29  ARG A CA    1 
ATOM   3    C C     . ARG A 1 29  ? 139.000 170.711 144.954 1.00 90.11  ? 29  ARG A C     1 
ATOM   4    O O     . ARG A 1 29  ? 138.735 171.615 145.746 1.00 85.73  ? 29  ARG A O     1 
ATOM   5    C CB    . ARG A 1 29  ? 137.227 170.071 143.300 1.00 93.00  ? 29  ARG A CB    1 
ATOM   6    C CG    . ARG A 1 29  ? 136.115 170.551 144.223 1.00 89.31  ? 29  ARG A CG    1 
ATOM   7    C CD    . ARG A 1 29  ? 134.823 169.784 143.987 1.00 89.74  ? 29  ARG A CD    1 
ATOM   8    N NE    . ARG A 1 29  ? 134.278 170.019 142.654 1.00 100.56 ? 29  ARG A NE    1 
ATOM   9    C CZ    . ARG A 1 29  ? 133.136 169.512 142.212 1.00 100.89 ? 29  ARG A CZ    1 
ATOM   10   N NH1   . ARG A 1 29  ? 132.386 168.731 142.972 1.00 102.36 ? 29  ARG A NH1   1 
ATOM   11   N NH2   . ARG A 1 29  ? 132.735 169.797 140.976 1.00 92.07  ? 29  ARG A NH2   1 
ATOM   12   N N     . ILE A 1 30  ? 139.676 169.613 145.303 1.00 86.97  ? 30  ILE A N     1 
ATOM   13   C CA    . ILE A 1 30  ? 140.121 169.418 146.677 1.00 82.81  ? 30  ILE A CA    1 
ATOM   14   C C     . ILE A 1 30  ? 141.217 170.399 147.071 1.00 83.92  ? 30  ILE A C     1 
ATOM   15   O O     . ILE A 1 30  ? 141.414 170.650 148.266 1.00 79.48  ? 30  ILE A O     1 
ATOM   16   C CB    . ILE A 1 30  ? 140.595 167.968 146.893 1.00 80.41  ? 30  ILE A CB    1 
ATOM   17   C CG1   . ILE A 1 30  ? 141.783 167.649 145.983 1.00 81.21  ? 30  ILE A CG1   1 
ATOM   18   C CG2   . ILE A 1 30  ? 139.455 166.993 146.648 1.00 71.67  ? 30  ILE A CG2   1 
ATOM   19   C CD1   . ILE A 1 30  ? 142.352 166.261 146.191 1.00 77.31  ? 30  ILE A CD1   1 
ATOM   20   N N     . GLN A 1 31  ? 141.941 170.961 146.099 1.00 86.14  ? 31  GLN A N     1 
ATOM   21   C CA    . GLN A 1 31  ? 143.012 171.899 146.422 1.00 80.52  ? 31  GLN A CA    1 
ATOM   22   C C     . GLN A 1 31  ? 142.475 173.180 147.048 1.00 75.89  ? 31  GLN A C     1 
ATOM   23   O O     . GLN A 1 31  ? 143.192 173.846 147.803 1.00 67.89  ? 31  GLN A O     1 
ATOM   24   C CB    . GLN A 1 31  ? 143.826 172.226 145.169 1.00 80.27  ? 31  GLN A CB    1 
ATOM   25   C CG    . GLN A 1 31  ? 144.538 171.033 144.546 1.00 87.23  ? 31  GLN A CG    1 
ATOM   26   C CD    . GLN A 1 31  ? 143.675 170.289 143.543 1.00 94.18  ? 31  GLN A CD    1 
ATOM   27   O OE1   . GLN A 1 31  ? 142.526 170.657 143.299 1.00 94.40  ? 31  GLN A OE1   1 
ATOM   28   N NE2   . GLN A 1 31  ? 144.231 169.237 142.952 1.00 94.55  ? 31  GLN A NE2   1 
ATOM   29   N N     . GLY A 1 32  ? 141.228 173.536 146.756 1.00 77.02  ? 32  GLY A N     1 
ATOM   30   C CA    . GLY A 1 32  ? 140.638 174.747 147.283 1.00 74.81  ? 32  GLY A CA    1 
ATOM   31   C C     . GLY A 1 32  ? 140.145 174.669 148.708 1.00 73.05  ? 32  GLY A C     1 
ATOM   32   O O     . GLY A 1 32  ? 139.682 175.678 149.246 1.00 70.70  ? 32  GLY A O     1 
ATOM   33   N N     . ALA A 1 33  ? 140.228 173.503 149.340 1.00 68.62  ? 33  ALA A N     1 
ATOM   34   C CA    . ALA A 1 33  ? 139.750 173.307 150.701 1.00 53.81  ? 33  ALA A CA    1 
ATOM   35   C C     . ALA A 1 33  ? 140.930 173.129 151.645 1.00 50.32  ? 33  ALA A C     1 
ATOM   36   O O     . ALA A 1 33  ? 141.847 172.350 151.363 1.00 47.43  ? 33  ALA A O     1 
ATOM   37   C CB    . ALA A 1 33  ? 138.819 172.099 150.787 1.00 49.63  ? 33  ALA A CB    1 
ATOM   38   N N     . LYS A 1 34  ? 140.895 173.847 152.763 1.00 48.77  ? 34  LYS A N     1 
ATOM   39   C CA    . LYS A 1 34  ? 141.928 173.799 153.788 1.00 41.39  ? 34  LYS A CA    1 
ATOM   40   C C     . LYS A 1 34  ? 141.394 173.028 154.986 1.00 39.23  ? 34  LYS A C     1 
ATOM   41   O O     . LYS A 1 34  ? 140.261 173.258 155.419 1.00 41.07  ? 34  LYS A O     1 
ATOM   42   C CB    . LYS A 1 34  ? 142.341 175.213 154.202 1.00 40.40  ? 34  LYS A CB    1 
ATOM   43   C CG    . LYS A 1 34  ? 143.652 175.300 154.951 1.00 40.86  ? 34  LYS A CG    1 
ATOM   44   C CD    . LYS A 1 34  ? 143.815 176.671 155.584 1.00 42.58  ? 34  LYS A CD    1 
ATOM   45   C CE    . LYS A 1 34  ? 143.530 177.779 154.588 1.00 47.20  ? 34  LYS A CE    1 
ATOM   46   N NZ    . LYS A 1 34  ? 143.598 179.123 155.224 1.00 62.41  ? 34  LYS A NZ    1 
ATOM   47   N N     . VAL A 1 35  ? 142.205 172.118 155.518 1.00 38.42  ? 35  VAL A N     1 
ATOM   48   C CA    . VAL A 1 35  ? 141.781 171.200 156.569 1.00 38.01  ? 35  VAL A CA    1 
ATOM   49   C C     . VAL A 1 35  ? 142.581 171.482 157.831 1.00 37.20  ? 35  VAL A C     1 
ATOM   50   O O     . VAL A 1 35  ? 143.811 171.604 157.782 1.00 39.39  ? 35  VAL A O     1 
ATOM   51   C CB    . VAL A 1 35  ? 141.946 169.734 156.137 1.00 40.28  ? 35  VAL A CB    1 
ATOM   52   C CG1   . VAL A 1 35  ? 141.285 168.805 157.144 1.00 42.42  ? 35  VAL A CG1   1 
ATOM   53   C CG2   . VAL A 1 35  ? 141.370 169.524 154.755 1.00 40.89  ? 35  VAL A CG2   1 
ATOM   54   N N     . LEU A 1 36  ? 141.882 171.587 158.957 1.00 36.75  ? 36  LEU A N     1 
ATOM   55   C CA    . LEU A 1 36  ? 142.498 171.668 160.273 1.00 33.48  ? 36  LEU A CA    1 
ATOM   56   C C     . LEU A 1 36  ? 142.453 170.293 160.920 1.00 33.78  ? 36  LEU A C     1 
ATOM   57   O O     . LEU A 1 36  ? 141.427 169.610 160.859 1.00 37.80  ? 36  LEU A O     1 
ATOM   58   C CB    . LEU A 1 36  ? 141.779 172.688 161.155 1.00 30.04  ? 36  LEU A CB    1 
ATOM   59   C CG    . LEU A 1 36  ? 142.168 172.709 162.632 1.00 26.26  ? 36  LEU A CG    1 
ATOM   60   C CD1   . LEU A 1 36  ? 143.640 173.044 162.805 1.00 29.45  ? 36  LEU A CD1   1 
ATOM   61   C CD2   . LEU A 1 36  ? 141.295 173.692 163.385 1.00 31.32  ? 36  LEU A CD2   1 
ATOM   62   N N     . LEU A 1 37  ? 143.563 169.884 161.524 1.00 32.36  ? 37  LEU A N     1 
ATOM   63   C CA    . LEU A 1 37  ? 143.671 168.574 162.154 1.00 28.94  ? 37  LEU A CA    1 
ATOM   64   C C     . LEU A 1 37  ? 144.283 168.745 163.536 1.00 32.86  ? 37  LEU A C     1 
ATOM   65   O O     . LEU A 1 37  ? 145.484 169.007 163.658 1.00 39.47  ? 37  LEU A O     1 
ATOM   66   C CB    . LEU A 1 37  ? 144.508 167.623 161.298 1.00 30.83  ? 37  LEU A CB    1 
ATOM   67   C CG    . LEU A 1 37  ? 144.800 166.239 161.873 1.00 34.39  ? 37  LEU A CG    1 
ATOM   68   C CD1   . LEU A 1 37  ? 143.517 165.510 162.215 1.00 32.78  ? 37  LEU A CD1   1 
ATOM   69   C CD2   . LEU A 1 37  ? 145.620 165.435 160.887 1.00 36.48  ? 37  LEU A CD2   1 
ATOM   70   N N     . SER A 1 38  ? 143.465 168.597 164.571 1.00 32.33  ? 38  SER A N     1 
ATOM   71   C CA    . SER A 1 38  ? 143.927 168.645 165.947 1.00 34.40  ? 38  SER A CA    1 
ATOM   72   C C     . SER A 1 38  ? 144.044 167.230 166.493 1.00 31.05  ? 38  SER A C     1 
ATOM   73   O O     . SER A 1 38  ? 143.178 166.385 166.252 1.00 31.08  ? 38  SER A O     1 
ATOM   74   C CB    . SER A 1 38  ? 142.978 169.468 166.817 1.00 36.06  ? 38  SER A CB    1 
ATOM   75   O OG    . SER A 1 38  ? 143.411 169.489 168.166 1.00 43.77  ? 38  SER A OG    1 
ATOM   76   N N     . GLY A 1 39  ? 145.123 166.979 167.221 1.00 31.18  ? 39  GLY A N     1 
ATOM   77   C CA    . GLY A 1 39  ? 145.421 165.647 167.699 1.00 32.18  ? 39  GLY A CA    1 
ATOM   78   C C     . GLY A 1 39  ? 146.305 164.911 166.720 1.00 36.09  ? 39  GLY A C     1 
ATOM   79   O O     . GLY A 1 39  ? 145.907 164.665 165.578 1.00 38.87  ? 39  GLY A O     1 
ATOM   80   N N     . LEU A 1 40  ? 147.509 164.557 167.150 1.00 39.62  ? 40  LEU A N     1 
ATOM   81   C CA    . LEU A 1 40  ? 148.486 163.895 166.300 1.00 39.07  ? 40  LEU A CA    1 
ATOM   82   C C     . LEU A 1 40  ? 148.926 162.570 166.907 1.00 38.56  ? 40  LEU A C     1 
ATOM   83   O O     . LEU A 1 40  ? 150.089 162.175 166.816 1.00 34.86  ? 40  LEU A O     1 
ATOM   84   C CB    . LEU A 1 40  ? 149.685 164.803 166.038 1.00 40.49  ? 40  LEU A CB    1 
ATOM   85   C CG    . LEU A 1 40  ? 149.743 165.450 164.650 1.00 43.62  ? 40  LEU A CG    1 
ATOM   86   C CD1   . LEU A 1 40  ? 149.961 164.392 163.581 1.00 43.56  ? 40  LEU A CD1   1 
ATOM   87   C CD2   . LEU A 1 40  ? 148.486 166.257 164.355 1.00 39.20  ? 40  LEU A CD2   1 
ATOM   88   N N     . GLN A 1 41  ? 147.990 161.870 167.543 1.00 40.41  ? 41  GLN A N     1 
ATOM   89   C CA    . GLN A 1 41  ? 148.193 160.470 167.868 1.00 40.82  ? 41  GLN A CA    1 
ATOM   90   C C     . GLN A 1 41  ? 148.175 159.651 166.579 1.00 38.82  ? 41  GLN A C     1 
ATOM   91   O O     . GLN A 1 41  ? 148.014 160.183 165.477 1.00 43.79  ? 41  GLN A O     1 
ATOM   92   C CB    . GLN A 1 41  ? 147.132 159.993 168.855 1.00 45.95  ? 41  GLN A CB    1 
ATOM   93   C CG    . GLN A 1 41  ? 145.705 160.089 168.342 1.00 48.77  ? 41  GLN A CG    1 
ATOM   94   C CD    . GLN A 1 41  ? 144.699 159.554 169.340 1.00 59.78  ? 41  GLN A CD    1 
ATOM   95   O OE1   . GLN A 1 41  ? 145.056 159.180 170.457 1.00 66.46  ? 41  GLN A OE1   1 
ATOM   96   N NE2   . GLN A 1 41  ? 143.432 159.512 168.944 1.00 48.72  ? 41  GLN A NE2   1 
ATOM   97   N N     . GLY A 1 42  ? 148.357 158.336 166.712 1.00 31.96  ? 42  GLY A N     1 
ATOM   98   C CA    . GLY A 1 42  ? 148.416 157.483 165.534 1.00 30.41  ? 42  GLY A CA    1 
ATOM   99   C C     . GLY A 1 42  ? 147.211 157.623 164.627 1.00 31.63  ? 42  GLY A C     1 
ATOM   100  O O     . GLY A 1 42  ? 147.332 157.524 163.401 1.00 36.31  ? 42  GLY A O     1 
ATOM   101  N N     . LEU A 1 43  ? 146.036 157.864 165.209 1.00 29.75  ? 43  LEU A N     1 
ATOM   102  C CA    . LEU A 1 43  ? 144.837 158.078 164.408 1.00 31.03  ? 43  LEU A CA    1 
ATOM   103  C C     . LEU A 1 43  ? 144.947 159.359 163.591 1.00 33.84  ? 43  LEU A C     1 
ATOM   104  O O     . LEU A 1 43  ? 144.631 159.381 162.393 1.00 38.43  ? 43  LEU A O     1 
ATOM   105  C CB    . LEU A 1 43  ? 143.617 158.119 165.321 1.00 32.27  ? 43  LEU A CB    1 
ATOM   106  C CG    . LEU A 1 43  ? 142.266 158.119 164.626 1.00 28.68  ? 43  LEU A CG    1 
ATOM   107  C CD1   . LEU A 1 43  ? 142.107 156.864 163.815 1.00 31.03  ? 43  LEU A CD1   1 
ATOM   108  C CD2   . LEU A 1 43  ? 141.181 158.211 165.658 1.00 26.98  ? 43  LEU A CD2   1 
ATOM   109  N N     . GLY A 1 44  ? 145.394 160.440 164.229 1.00 30.26  ? 44  GLY A N     1 
ATOM   110  C CA    . GLY A 1 44  ? 145.631 161.670 163.499 1.00 29.97  ? 44  GLY A CA    1 
ATOM   111  C C     . GLY A 1 44  ? 146.705 161.512 162.444 1.00 31.15  ? 44  GLY A C     1 
ATOM   112  O O     . GLY A 1 44  ? 146.626 162.112 161.372 1.00 36.72  ? 44  GLY A O     1 
ATOM   113  N N     . ALA A 1 45  ? 147.722 160.698 162.731 1.00 29.19  ? 45  ALA A N     1 
ATOM   114  C CA    . ALA A 1 45  ? 148.750 160.423 161.735 1.00 29.81  ? 45  ALA A CA    1 
ATOM   115  C C     . ALA A 1 45  ? 148.166 159.712 160.526 1.00 33.31  ? 45  ALA A C     1 
ATOM   116  O O     . ALA A 1 45  ? 148.529 160.017 159.387 1.00 38.86  ? 45  ALA A O     1 
ATOM   117  C CB    . ALA A 1 45  ? 149.875 159.593 162.346 1.00 29.66  ? 45  ALA A CB    1 
ATOM   118  N N     . GLU A 1 46  ? 147.262 158.756 160.751 1.00 34.08  ? 46  GLU A N     1 
ATOM   119  C CA    . GLU A 1 46  ? 146.624 158.064 159.634 1.00 33.52  ? 46  GLU A CA    1 
ATOM   120  C C     . GLU A 1 46  ? 145.769 159.019 158.809 1.00 34.20  ? 46  GLU A C     1 
ATOM   121  O O     . GLU A 1 46  ? 145.822 159.009 157.570 1.00 41.80  ? 46  GLU A O     1 
ATOM   122  C CB    . GLU A 1 46  ? 145.786 156.897 160.155 1.00 34.82  ? 46  GLU A CB    1 
ATOM   123  C CG    . GLU A 1 46  ? 146.611 155.756 160.720 1.00 38.64  ? 46  GLU A CG    1 
ATOM   124  C CD    . GLU A 1 46  ? 147.420 155.038 159.658 1.00 43.72  ? 46  GLU A CD    1 
ATOM   125  O OE1   . GLU A 1 46  ? 146.951 154.952 158.503 1.00 46.52  ? 46  GLU A OE1   1 
ATOM   126  O OE2   . GLU A 1 46  ? 148.529 154.561 159.977 1.00 43.20  ? 46  GLU A OE2   1 
ATOM   127  N N     . VAL A 1 47  ? 144.973 159.854 159.482 1.00 30.55  ? 47  VAL A N     1 
ATOM   128  C CA    . VAL A 1 47  ? 144.152 160.832 158.769 1.00 31.76  ? 47  VAL A CA    1 
ATOM   129  C C     . VAL A 1 47  ? 145.035 161.757 157.941 1.00 36.31  ? 47  VAL A C     1 
ATOM   130  O O     . VAL A 1 47  ? 144.770 162.010 156.758 1.00 42.43  ? 47  VAL A O     1 
ATOM   131  C CB    . VAL A 1 47  ? 143.277 161.626 159.754 1.00 29.54  ? 47  VAL A CB    1 
ATOM   132  C CG1   . VAL A 1 47  ? 142.462 162.671 159.014 1.00 31.00  ? 47  VAL A CG1   1 
ATOM   133  C CG2   . VAL A 1 47  ? 142.371 160.699 160.530 1.00 34.68  ? 47  VAL A CG2   1 
ATOM   134  N N     . ALA A 1 48  ? 146.104 162.270 158.553 1.00 30.33  ? 48  ALA A N     1 
ATOM   135  C CA    . ALA A 1 48  ? 147.001 163.183 157.860 1.00 28.04  ? 48  ALA A CA    1 
ATOM   136  C C     . ALA A 1 48  ? 147.680 162.504 156.681 1.00 33.97  ? 48  ALA A C     1 
ATOM   137  O O     . ALA A 1 48  ? 147.815 163.102 155.608 1.00 43.88  ? 48  ALA A O     1 
ATOM   138  C CB    . ALA A 1 48  ? 148.037 163.731 158.836 1.00 26.03  ? 48  ALA A CB    1 
ATOM   139  N N     . LYS A 1 49  ? 148.118 161.257 156.859 1.00 29.83  ? 49  LYS A N     1 
ATOM   140  C CA    . LYS A 1 49  ? 148.761 160.534 155.771 1.00 32.50  ? 49  LYS A CA    1 
ATOM   141  C C     . LYS A 1 49  ? 147.814 160.370 154.596 1.00 34.32  ? 49  LYS A C     1 
ATOM   142  O O     . LYS A 1 49  ? 148.187 160.623 153.446 1.00 41.82  ? 49  LYS A O     1 
ATOM   143  C CB    . LYS A 1 49  ? 149.254 159.171 156.255 1.00 34.56  ? 49  LYS A CB    1 
ATOM   144  C CG    . LYS A 1 49  ? 149.850 158.313 155.150 1.00 36.90  ? 49  LYS A CG    1 
ATOM   145  C CD    . LYS A 1 49  ? 150.329 156.974 155.674 1.00 39.83  ? 49  LYS A CD    1 
ATOM   146  C CE    . LYS A 1 49  ? 149.211 156.209 156.363 1.00 36.52  ? 49  LYS A CE    1 
ATOM   147  N NZ    . LYS A 1 49  ? 148.095 155.888 155.441 1.00 37.72  ? 49  LYS A NZ    1 
ATOM   148  N N     . ASN A 1 50  ? 146.576 159.950 154.865 1.00 31.54  ? 50  ASN A N     1 
ATOM   149  C CA    . ASN A 1 50  ? 145.623 159.759 153.777 1.00 37.03  ? 50  ASN A CA    1 
ATOM   150  C C     . ASN A 1 50  ? 145.316 161.073 153.068 1.00 42.92  ? 50  ASN A C     1 
ATOM   151  O O     . ASN A 1 50  ? 145.285 161.129 151.831 1.00 53.08  ? 50  ASN A O     1 
ATOM   152  C CB    . ASN A 1 50  ? 144.336 159.127 154.304 1.00 36.35  ? 50  ASN A CB    1 
ATOM   153  C CG    . ASN A 1 50  ? 144.577 157.820 155.029 1.00 34.34  ? 50  ASN A CG    1 
ATOM   154  O OD1   . ASN A 1 50  ? 145.559 157.127 154.779 1.00 37.62  ? 50  ASN A OD1   1 
ATOM   155  N ND2   . ASN A 1 50  ? 143.671 157.476 155.934 1.00 34.79  ? 50  ASN A ND2   1 
ATOM   156  N N     . LEU A 1 51  ? 145.093 162.145 153.834 1.00 36.51  ? 51  LEU A N     1 
ATOM   157  C CA    . LEU A 1 51  ? 144.764 163.430 153.225 1.00 35.70  ? 51  LEU A CA    1 
ATOM   158  C C     . LEU A 1 51  ? 145.925 163.967 152.398 1.00 39.13  ? 51  LEU A C     1 
ATOM   159  O O     . LEU A 1 51  ? 145.718 164.517 151.310 1.00 48.50  ? 51  LEU A O     1 
ATOM   160  C CB    . LEU A 1 51  ? 144.358 164.432 154.302 1.00 32.11  ? 51  LEU A CB    1 
ATOM   161  C CG    . LEU A 1 51  ? 143.087 164.077 155.070 1.00 34.90  ? 51  LEU A CG    1 
ATOM   162  C CD1   . LEU A 1 51  ? 142.700 165.203 156.013 1.00 34.15  ? 51  LEU A CD1   1 
ATOM   163  C CD2   . LEU A 1 51  ? 141.953 163.755 154.113 1.00 44.05  ? 51  LEU A CD2   1 
ATOM   164  N N     . VAL A 1 52  ? 147.152 163.821 152.896 1.00 35.01  ? 52  VAL A N     1 
ATOM   165  C CA    . VAL A 1 52  ? 148.319 164.277 152.153 1.00 40.42  ? 52  VAL A CA    1 
ATOM   166  C C     . VAL A 1 52  ? 148.517 163.444 150.893 1.00 46.98  ? 52  VAL A C     1 
ATOM   167  O O     . VAL A 1 52  ? 148.829 163.981 149.823 1.00 53.61  ? 52  VAL A O     1 
ATOM   168  C CB    . VAL A 1 52  ? 149.557 164.252 153.067 1.00 36.31  ? 52  VAL A CB    1 
ATOM   169  C CG1   . VAL A 1 52  ? 150.829 164.384 152.261 1.00 42.55  ? 52  VAL A CG1   1 
ATOM   170  C CG2   . VAL A 1 52  ? 149.464 165.366 154.087 1.00 39.07  ? 52  VAL A CG2   1 
ATOM   171  N N     . LEU A 1 53  ? 148.337 162.123 150.990 1.00 44.73  ? 53  LEU A N     1 
ATOM   172  C CA    . LEU A 1 53  ? 148.528 161.262 149.828 1.00 45.51  ? 53  LEU A CA    1 
ATOM   173  C C     . LEU A 1 53  ? 147.499 161.549 148.743 1.00 51.06  ? 53  LEU A C     1 
ATOM   174  O O     . LEU A 1 53  ? 147.834 161.560 147.553 1.00 57.04  ? 53  LEU A O     1 
ATOM   175  C CB    . LEU A 1 53  ? 148.473 159.794 150.242 1.00 45.24  ? 53  LEU A CB    1 
ATOM   176  C CG    . LEU A 1 53  ? 149.700 159.257 150.975 1.00 47.59  ? 53  LEU A CG    1 
ATOM   177  C CD1   . LEU A 1 53  ? 149.501 157.793 151.322 1.00 47.83  ? 53  LEU A CD1   1 
ATOM   178  C CD2   . LEU A 1 53  ? 150.944 159.450 150.133 1.00 50.49  ? 53  LEU A CD2   1 
ATOM   179  N N     . MET A 1 54  ? 146.239 161.777 149.123 1.00 50.65  ? 54  MET A N     1 
ATOM   180  C CA    . MET A 1 54  ? 145.252 162.088 148.098 1.00 60.91  ? 54  MET A CA    1 
ATOM   181  C C     . MET A 1 54  ? 145.480 163.462 147.479 1.00 63.39  ? 54  MET A C     1 
ATOM   182  O O     . MET A 1 54  ? 145.051 163.700 146.344 1.00 68.14  ? 54  MET A O     1 
ATOM   183  C CB    . MET A 1 54  ? 143.832 161.994 148.658 1.00 58.41  ? 54  MET A CB    1 
ATOM   184  C CG    . MET A 1 54  ? 142.777 162.028 147.552 1.00 72.52  ? 54  MET A CG    1 
ATOM   185  S SD    . MET A 1 54  ? 141.273 161.094 147.874 1.00 93.70  ? 54  MET A SD    1 
ATOM   186  C CE    . MET A 1 54  ? 141.951 159.531 148.420 1.00 66.48  ? 54  MET A CE    1 
ATOM   187  N N     . GLY A 1 55  ? 146.170 164.356 148.179 1.00 55.41  ? 55  GLY A N     1 
ATOM   188  C CA    . GLY A 1 55  ? 146.515 165.640 147.611 1.00 55.90  ? 55  GLY A CA    1 
ATOM   189  C C     . GLY A 1 55  ? 145.633 166.796 148.010 1.00 56.00  ? 55  GLY A C     1 
ATOM   190  O O     . GLY A 1 55  ? 145.446 167.719 147.210 1.00 65.15  ? 55  GLY A O     1 
ATOM   191  N N     . VAL A 1 56  ? 145.073 166.779 149.218 1.00 50.39  ? 56  VAL A N     1 
ATOM   192  C CA    . VAL A 1 56  ? 144.421 167.972 149.744 1.00 53.72  ? 56  VAL A CA    1 
ATOM   193  C C     . VAL A 1 56  ? 145.486 169.047 149.912 1.00 55.20  ? 56  VAL A C     1 
ATOM   194  O O     . VAL A 1 56  ? 146.443 168.877 150.675 1.00 56.92  ? 56  VAL A O     1 
ATOM   195  C CB    . VAL A 1 56  ? 143.706 167.676 151.067 1.00 48.40  ? 56  VAL A CB    1 
ATOM   196  C CG1   . VAL A 1 56  ? 142.981 168.908 151.558 1.00 46.22  ? 56  VAL A CG1   1 
ATOM   197  C CG2   . VAL A 1 56  ? 142.735 166.519 150.895 1.00 50.33  ? 56  VAL A CG2   1 
ATOM   198  N N     . GLY A 1 57  ? 145.322 170.159 149.196 1.00 56.11  ? 57  GLY A N     1 
ATOM   199  C CA    . GLY A 1 57  ? 146.413 171.099 149.008 1.00 49.43  ? 57  GLY A CA    1 
ATOM   200  C C     . GLY A 1 57  ? 146.922 171.756 150.273 1.00 46.75  ? 57  GLY A C     1 
ATOM   201  O O     . GLY A 1 57  ? 148.051 172.253 150.286 1.00 49.64  ? 57  GLY A O     1 
ATOM   202  N N     . SER A 1 58  ? 146.125 171.771 151.338 1.00 45.71  ? 58  SER A N     1 
ATOM   203  C CA    . SER A 1 58  ? 146.509 172.495 152.542 1.00 41.09  ? 58  SER A CA    1 
ATOM   204  C C     . SER A 1 58  ? 146.023 171.756 153.777 1.00 39.97  ? 58  SER A C     1 
ATOM   205  O O     . SER A 1 58  ? 144.842 171.414 153.876 1.00 40.55  ? 58  SER A O     1 
ATOM   206  C CB    . SER A 1 58  ? 145.951 173.920 152.517 1.00 41.21  ? 58  SER A CB    1 
ATOM   207  O OG    . SER A 1 58  ? 144.602 173.924 152.092 1.00 43.78  ? 58  SER A OG    1 
ATOM   208  N N     . LEU A 1 59  ? 146.940 171.520 154.713 1.00 41.31  ? 59  LEU A N     1 
ATOM   209  C CA    . LEU A 1 59  ? 146.639 170.852 155.969 1.00 37.04  ? 59  LEU A CA    1 
ATOM   210  C C     . LEU A 1 59  ? 147.416 171.527 157.089 1.00 33.40  ? 59  LEU A C     1 
ATOM   211  O O     . LEU A 1 59  ? 148.597 171.845 156.927 1.00 34.85  ? 59  LEU A O     1 
ATOM   212  C CB    . LEU A 1 59  ? 146.993 169.361 155.902 1.00 38.92  ? 59  LEU A CB    1 
ATOM   213  C CG    . LEU A 1 59  ? 146.660 168.485 157.109 1.00 37.13  ? 59  LEU A CG    1 
ATOM   214  C CD1   . LEU A 1 59  ? 145.175 168.522 157.409 1.00 33.37  ? 59  LEU A CD1   1 
ATOM   215  C CD2   . LEU A 1 59  ? 147.120 167.061 156.860 1.00 34.15  ? 59  LEU A CD2   1 
ATOM   216  N N     . THR A 1 60  ? 146.749 171.749 158.218 1.00 32.50  ? 60  THR A N     1 
ATOM   217  C CA    . THR A 1 60  ? 147.371 172.335 159.398 1.00 28.10  ? 60  THR A CA    1 
ATOM   218  C C     . THR A 1 60  ? 147.239 171.370 160.566 1.00 35.55  ? 60  THR A C     1 
ATOM   219  O O     . THR A 1 60  ? 146.141 170.887 160.857 1.00 37.47  ? 60  THR A O     1 
ATOM   220  C CB    . THR A 1 60  ? 146.740 173.679 159.757 1.00 28.42  ? 60  THR A CB    1 
ATOM   221  O OG1   . THR A 1 60  ? 146.820 174.561 158.630 1.00 40.79  ? 60  THR A OG1   1 
ATOM   222  C CG2   . THR A 1 60  ? 147.470 174.305 160.929 1.00 30.34  ? 60  THR A CG2   1 
ATOM   223  N N     . LEU A 1 61  ? 148.356 171.096 161.228 1.00 34.56  ? 61  LEU A N     1 
ATOM   224  C CA    . LEU A 1 61  ? 148.409 170.178 162.352 1.00 27.24  ? 61  LEU A CA    1 
ATOM   225  C C     . LEU A 1 61  ? 148.415 170.955 163.660 1.00 26.28  ? 61  LEU A C     1 
ATOM   226  O O     . LEU A 1 61  ? 148.932 172.071 163.737 1.00 36.14  ? 61  LEU A O     1 
ATOM   227  C CB    . LEU A 1 61  ? 149.655 169.298 162.275 1.00 30.54  ? 61  LEU A CB    1 
ATOM   228  C CG    . LEU A 1 61  ? 150.109 168.861 160.886 1.00 30.86  ? 61  LEU A CG    1 
ATOM   229  C CD1   . LEU A 1 61  ? 151.446 168.163 160.988 1.00 31.44  ? 61  LEU A CD1   1 
ATOM   230  C CD2   . LEU A 1 61  ? 149.074 167.957 160.242 1.00 33.81  ? 61  LEU A CD2   1 
ATOM   231  N N     . HIS A 1 62  ? 147.839 170.350 164.696 1.00 24.14  ? 62  HIS A N     1 
ATOM   232  C CA    . HIS A 1 62  ? 147.789 170.989 166.008 1.00 26.88  ? 62  HIS A CA    1 
ATOM   233  C C     . HIS A 1 62  ? 147.803 169.899 167.073 1.00 37.41  ? 62  HIS A C     1 
ATOM   234  O O     . HIS A 1 62  ? 146.783 169.246 167.308 1.00 43.35  ? 62  HIS A O     1 
ATOM   235  C CB    . HIS A 1 62  ? 146.563 171.876 166.147 1.00 29.96  ? 62  HIS A CB    1 
ATOM   236  C CG    . HIS A 1 62  ? 146.331 172.356 167.544 1.00 34.80  ? 62  HIS A CG    1 
ATOM   237  N ND1   . HIS A 1 62  ? 145.338 171.845 168.351 1.00 39.05  ? 62  HIS A ND1   1 
ATOM   238  C CD2   . HIS A 1 62  ? 146.973 173.290 168.283 1.00 40.76  ? 62  HIS A CD2   1 
ATOM   239  C CE1   . HIS A 1 62  ? 145.374 172.449 169.525 1.00 43.78  ? 62  HIS A CE1   1 
ATOM   240  N NE2   . HIS A 1 62  ? 146.356 173.331 169.510 1.00 44.86  ? 62  HIS A NE2   1 
ATOM   241  N N     . ASP A 1 63  ? 148.948 169.722 167.718 1.00 42.83  ? 63  ASP A N     1 
ATOM   242  C CA    . ASP A 1 63  ? 149.033 168.857 168.884 1.00 42.04  ? 63  ASP A CA    1 
ATOM   243  C C     . ASP A 1 63  ? 150.207 169.294 169.747 1.00 46.10  ? 63  ASP A C     1 
ATOM   244  O O     . ASP A 1 63  ? 151.299 168.719 169.652 1.00 49.42  ? 63  ASP A O     1 
ATOM   245  C CB    . ASP A 1 63  ? 149.180 167.393 168.474 1.00 41.48  ? 63  ASP A CB    1 
ATOM   246  C CG    . ASP A 1 63  ? 148.920 166.442 169.622 1.00 48.62  ? 63  ASP A CG    1 
ATOM   247  O OD1   . ASP A 1 63  ? 148.567 166.916 170.722 1.00 55.80  ? 63  ASP A OD1   1 
ATOM   248  O OD2   . ASP A 1 63  ? 149.067 165.220 169.426 1.00 46.99  ? 63  ASP A OD2   1 
ATOM   249  N N     . PRO A 1 64  ? 150.023 170.304 170.602 1.00 44.78  ? 64  PRO A N     1 
ATOM   250  C CA    . PRO A 1 64  ? 151.146 170.802 171.409 1.00 49.80  ? 64  PRO A CA    1 
ATOM   251  C C     . PRO A 1 64  ? 151.659 169.800 172.425 1.00 52.51  ? 64  PRO A C     1 
ATOM   252  O O     . PRO A 1 64  ? 152.768 169.989 172.942 1.00 55.21  ? 64  PRO A O     1 
ATOM   253  C CB    . PRO A 1 64  ? 150.556 172.036 172.101 1.00 51.17  ? 64  PRO A CB    1 
ATOM   254  C CG    . PRO A 1 64  ? 149.097 171.734 172.197 1.00 46.71  ? 64  PRO A CG    1 
ATOM   255  C CD    . PRO A 1 64  ? 148.754 170.965 170.951 1.00 46.83  ? 64  PRO A CD    1 
ATOM   256  N N     . HIS A 1 65  ? 150.895 168.755 172.723 1.00 51.40  ? 65  HIS A N     1 
ATOM   257  C CA    . HIS A 1 65  ? 151.291 167.810 173.753 1.00 48.11  ? 65  HIS A CA    1 
ATOM   258  C C     . HIS A 1 65  ? 152.611 167.144 173.379 1.00 44.73  ? 65  HIS A C     1 
ATOM   259  O O     . HIS A 1 65  ? 152.807 166.759 172.220 1.00 44.93  ? 65  HIS A O     1 
ATOM   260  C CB    . HIS A 1 65  ? 150.206 166.751 173.954 1.00 48.78  ? 65  HIS A CB    1 
ATOM   261  C CG    . HIS A 1 65  ? 148.932 167.293 174.519 1.00 66.03  ? 65  HIS A CG    1 
ATOM   262  N ND1   . HIS A 1 65  ? 148.152 168.212 173.851 1.00 71.56  ? 65  HIS A ND1   1 
ATOM   263  C CD2   . HIS A 1 65  ? 148.302 167.049 175.692 1.00 79.35  ? 65  HIS A CD2   1 
ATOM   264  C CE1   . HIS A 1 65  ? 147.096 168.508 174.587 1.00 81.89  ? 65  HIS A CE1   1 
ATOM   265  N NE2   . HIS A 1 65  ? 147.163 167.816 175.709 1.00 88.40  ? 65  HIS A NE2   1 
ATOM   266  N N     . PRO A 1 66  ? 153.535 167.000 174.324 1.00 40.63  ? 66  PRO A N     1 
ATOM   267  C CA    . PRO A 1 66  ? 154.812 166.354 174.014 1.00 34.54  ? 66  PRO A CA    1 
ATOM   268  C C     . PRO A 1 66  ? 154.624 164.887 173.671 1.00 32.64  ? 66  PRO A C     1 
ATOM   269  O O     . PRO A 1 66  ? 153.696 164.225 174.143 1.00 39.03  ? 66  PRO A O     1 
ATOM   270  C CB    . PRO A 1 66  ? 155.615 166.524 175.307 1.00 30.11  ? 66  PRO A CB    1 
ATOM   271  C CG    . PRO A 1 66  ? 154.581 166.638 176.368 1.00 32.29  ? 66  PRO A CG    1 
ATOM   272  C CD    . PRO A 1 66  ? 153.440 167.381 175.743 1.00 38.02  ? 66  PRO A CD    1 
ATOM   273  N N     . THR A 1 67  ? 155.519 164.385 172.829 1.00 30.66  ? 67  THR A N     1 
ATOM   274  C CA    . THR A 1 67  ? 155.481 162.981 172.453 1.00 34.39  ? 67  THR A CA    1 
ATOM   275  C C     . THR A 1 67  ? 155.744 162.104 173.670 1.00 38.17  ? 67  THR A C     1 
ATOM   276  O O     . THR A 1 67  ? 156.648 162.371 174.466 1.00 40.96  ? 67  THR A O     1 
ATOM   277  C CB    . THR A 1 67  ? 156.514 162.696 171.362 1.00 33.56  ? 67  THR A CB    1 
ATOM   278  O OG1   . THR A 1 67  ? 156.283 163.565 170.247 1.00 36.12  ? 67  THR A OG1   1 
ATOM   279  C CG2   . THR A 1 67  ? 156.418 161.255 170.892 1.00 34.93  ? 67  THR A CG2   1 
ATOM   280  N N     . CYS A 1 68  ? 154.938 161.059 173.816 1.00 36.38  ? 68  CYS A N     1 
ATOM   281  C CA    . CYS A 1 68  ? 155.100 160.076 174.873 1.00 34.81  ? 68  CYS A CA    1 
ATOM   282  C C     . CYS A 1 68  ? 155.296 158.699 174.258 1.00 36.04  ? 68  CYS A C     1 
ATOM   283  O O     . CYS A 1 68  ? 155.057 158.487 173.066 1.00 36.97  ? 68  CYS A O     1 
ATOM   284  C CB    . CYS A 1 68  ? 153.896 160.062 175.822 1.00 35.86  ? 68  CYS A CB    1 
ATOM   285  S SG    . CYS A 1 68  ? 154.010 161.232 177.195 1.00 75.58  ? 68  CYS A SG    1 
ATOM   286  N N     . TRP A 1 69  ? 155.746 157.761 175.089 1.00 29.30  ? 69  TRP A N     1 
ATOM   287  C CA    . TRP A 1 69  ? 155.974 156.403 174.617 1.00 23.01  ? 69  TRP A CA    1 
ATOM   288  C C     . TRP A 1 69  ? 154.687 155.710 174.196 1.00 25.76  ? 69  TRP A C     1 
ATOM   289  O O     . TRP A 1 69  ? 154.739 154.772 173.394 1.00 32.44  ? 69  TRP A O     1 
ATOM   290  C CB    . TRP A 1 69  ? 156.666 155.586 175.700 1.00 23.91  ? 69  TRP A CB    1 
ATOM   291  C CG    . TRP A 1 69  ? 158.014 156.092 176.065 1.00 23.51  ? 69  TRP A CG    1 
ATOM   292  C CD1   . TRP A 1 69  ? 158.317 156.955 177.072 1.00 26.77  ? 69  TRP A CD1   1 
ATOM   293  C CD2   . TRP A 1 69  ? 159.254 155.757 175.435 1.00 22.18  ? 69  TRP A CD2   1 
ATOM   294  N NE1   . TRP A 1 69  ? 159.670 157.182 177.108 1.00 27.69  ? 69  TRP A NE1   1 
ATOM   295  C CE2   . TRP A 1 69  ? 160.268 156.455 176.113 1.00 23.07  ? 69  TRP A CE2   1 
ATOM   296  C CE3   . TRP A 1 69  ? 159.605 154.932 174.363 1.00 23.14  ? 69  TRP A CE3   1 
ATOM   297  C CZ2   . TRP A 1 69  ? 161.605 156.357 175.754 1.00 21.97  ? 69  TRP A CZ2   1 
ATOM   298  C CZ3   . TRP A 1 69  ? 160.933 154.838 174.010 1.00 24.21  ? 69  TRP A CZ3   1 
ATOM   299  C CH2   . TRP A 1 69  ? 161.917 155.545 174.703 1.00 20.76  ? 69  TRP A CH2   1 
ATOM   300  N N     . SER A 1 70  ? 153.540 156.146 174.713 1.00 22.40  ? 70  SER A N     1 
ATOM   301  C CA    . SER A 1 70  ? 152.273 155.524 174.358 1.00 24.94  ? 70  SER A CA    1 
ATOM   302  C C     . SER A 1 70  ? 151.871 155.799 172.918 1.00 34.29  ? 70  SER A C     1 
ATOM   303  O O     . SER A 1 70  ? 150.922 155.178 172.427 1.00 38.45  ? 70  SER A O     1 
ATOM   304  C CB    . SER A 1 70  ? 151.171 156.001 175.303 1.00 31.90  ? 70  SER A CB    1 
ATOM   305  O OG    . SER A 1 70  ? 151.006 157.406 175.227 1.00 38.52  ? 70  SER A OG    1 
ATOM   306  N N     . ASP A 1 71  ? 152.563 156.710 172.236 1.00 34.66  ? 71  ASP A N     1 
ATOM   307  C CA    . ASP A 1 71  ? 152.243 157.061 170.863 1.00 28.77  ? 71  ASP A CA    1 
ATOM   308  C C     . ASP A 1 71  ? 153.101 156.337 169.836 1.00 27.79  ? 71  ASP A C     1 
ATOM   309  O O     . ASP A 1 71  ? 152.676 156.209 168.685 1.00 33.17  ? 71  ASP A O     1 
ATOM   310  C CB    . ASP A 1 71  ? 152.388 158.573 170.661 1.00 32.36  ? 71  ASP A CB    1 
ATOM   311  C CG    . ASP A 1 71  ? 151.542 159.371 171.629 1.00 43.79  ? 71  ASP A CG    1 
ATOM   312  O OD1   . ASP A 1 71  ? 150.426 158.918 171.957 1.00 48.89  ? 71  ASP A OD1   1 
ATOM   313  O OD2   . ASP A 1 71  ? 151.994 160.450 172.067 1.00 47.65  ? 71  ASP A OD2   1 
ATOM   314  N N     . LEU A 1 72  ? 154.283 155.854 170.220 1.00 28.80  ? 72  LEU A N     1 
ATOM   315  C CA    . LEU A 1 72  ? 155.193 155.234 169.262 1.00 29.74  ? 72  LEU A CA    1 
ATOM   316  C C     . LEU A 1 72  ? 154.692 153.896 168.734 1.00 30.19  ? 72  LEU A C     1 
ATOM   317  O O     . LEU A 1 72  ? 155.226 153.411 167.732 1.00 28.93  ? 72  LEU A O     1 
ATOM   318  C CB    . LEU A 1 72  ? 156.573 155.055 169.892 1.00 23.77  ? 72  LEU A CB    1 
ATOM   319  C CG    . LEU A 1 72  ? 157.304 156.347 170.251 1.00 26.39  ? 72  LEU A CG    1 
ATOM   320  C CD1   . LEU A 1 72  ? 158.652 156.045 170.869 1.00 28.04  ? 72  LEU A CD1   1 
ATOM   321  C CD2   . LEU A 1 72  ? 157.461 157.223 169.024 1.00 35.90  ? 72  LEU A CD2   1 
ATOM   322  N N     . ALA A 1 73  ? 153.692 153.290 169.373 1.00 29.81  ? 73  ALA A N     1 
ATOM   323  C CA    . ALA A 1 73  ? 153.132 152.037 168.887 1.00 30.30  ? 73  ALA A CA    1 
ATOM   324  C C     . ALA A 1 73  ? 152.153 152.229 167.737 1.00 33.47  ? 73  ALA A C     1 
ATOM   325  O O     . ALA A 1 73  ? 151.794 151.246 167.082 1.00 36.44  ? 73  ALA A O     1 
ATOM   326  C CB    . ALA A 1 73  ? 152.437 151.293 170.030 1.00 29.44  ? 73  ALA A CB    1 
ATOM   327  N N     . ALA A 1 74  ? 151.714 153.459 167.479 1.00 30.30  ? 74  ALA A N     1 
ATOM   328  C CA    . ALA A 1 74  ? 150.782 153.740 166.396 1.00 28.19  ? 74  ALA A CA    1 
ATOM   329  C C     . ALA A 1 74  ? 151.188 154.902 165.507 1.00 32.68  ? 74  ALA A C     1 
ATOM   330  O O     . ALA A 1 74  ? 150.650 155.017 164.400 1.00 38.87  ? 74  ALA A O     1 
ATOM   331  C CB    . ALA A 1 74  ? 149.381 154.023 166.955 1.00 30.40  ? 74  ALA A CB    1 
ATOM   332  N N     . GLN A 1 75  ? 152.103 155.763 165.942 1.00 30.62  ? 75  GLN A N     1 
ATOM   333  C CA    . GLN A 1 75  ? 152.485 156.951 165.184 1.00 28.90  ? 75  GLN A CA    1 
ATOM   334  C C     . GLN A 1 75  ? 153.719 156.629 164.354 1.00 33.15  ? 75  GLN A C     1 
ATOM   335  O O     . GLN A 1 75  ? 154.833 156.552 164.877 1.00 38.14  ? 75  GLN A O     1 
ATOM   336  C CB    . GLN A 1 75  ? 152.744 158.126 166.118 1.00 32.14  ? 75  GLN A CB    1 
ATOM   337  C CG    . GLN A 1 75  ? 153.200 159.376 165.398 1.00 36.26  ? 75  GLN A CG    1 
ATOM   338  C CD    . GLN A 1 75  ? 152.052 160.268 164.992 1.00 35.06  ? 75  GLN A CD    1 
ATOM   339  O OE1   . GLN A 1 75  ? 152.241 161.293 164.339 1.00 36.53  ? 75  GLN A OE1   1 
ATOM   340  N NE2   . GLN A 1 75  ? 150.853 159.884 165.381 1.00 37.51  ? 75  GLN A NE2   1 
ATOM   341  N N     . PHE A 1 76  ? 153.519 156.441 163.049 1.00 33.07  ? 76  PHE A N     1 
ATOM   342  C CA    . PHE A 1 76  ? 154.629 156.161 162.148 1.00 34.07  ? 76  PHE A CA    1 
ATOM   343  C C     . PHE A 1 76  ? 155.449 157.404 161.838 1.00 34.22  ? 76  PHE A C     1 
ATOM   344  O O     . PHE A 1 76  ? 156.586 157.283 161.368 1.00 36.34  ? 76  PHE A O     1 
ATOM   345  C CB    . PHE A 1 76  ? 154.106 155.539 160.851 1.00 37.28  ? 76  PHE A CB    1 
ATOM   346  C CG    . PHE A 1 76  ? 152.983 156.311 160.219 1.00 40.23  ? 76  PHE A CG    1 
ATOM   347  C CD1   . PHE A 1 76  ? 151.680 156.146 160.654 1.00 40.94  ? 76  PHE A CD1   1 
ATOM   348  C CD2   . PHE A 1 76  ? 153.228 157.200 159.187 1.00 37.09  ? 76  PHE A CD2   1 
ATOM   349  C CE1   . PHE A 1 76  ? 150.645 156.857 160.082 1.00 40.55  ? 76  PHE A CE1   1 
ATOM   350  C CE2   . PHE A 1 76  ? 152.194 157.910 158.606 1.00 38.43  ? 76  PHE A CE2   1 
ATOM   351  C CZ    . PHE A 1 76  ? 150.902 157.740 159.058 1.00 40.01  ? 76  PHE A CZ    1 
ATOM   352  N N     . LEU A 1 77  ? 154.899 158.593 162.077 1.00 34.55  ? 77  LEU A N     1 
ATOM   353  C CA    . LEU A 1 77  ? 155.638 159.821 161.828 1.00 35.81  ? 77  LEU A CA    1 
ATOM   354  C C     . LEU A 1 77  ? 156.666 160.119 162.911 1.00 36.25  ? 77  LEU A C     1 
ATOM   355  O O     . LEU A 1 77  ? 157.644 160.821 162.637 1.00 37.36  ? 77  LEU A O     1 
ATOM   356  C CB    . LEU A 1 77  ? 154.666 160.996 161.696 1.00 32.57  ? 77  LEU A CB    1 
ATOM   357  C CG    . LEU A 1 77  ? 153.617 160.848 160.594 1.00 31.07  ? 77  LEU A CG    1 
ATOM   358  C CD1   . LEU A 1 77  ? 152.712 162.057 160.549 1.00 33.34  ? 77  LEU A CD1   1 
ATOM   359  C CD2   . LEU A 1 77  ? 154.287 160.624 159.247 1.00 36.00  ? 77  LEU A CD2   1 
ATOM   360  N N     . LEU A 1 78  ? 156.481 159.592 164.116 1.00 32.81  ? 78  LEU A N     1 
ATOM   361  C CA    . LEU A 1 78  ? 157.322 159.919 165.255 1.00 32.73  ? 78  LEU A CA    1 
ATOM   362  C C     . LEU A 1 78  ? 158.192 158.732 165.644 1.00 38.09  ? 78  LEU A C     1 
ATOM   363  O O     . LEU A 1 78  ? 157.813 157.572 165.459 1.00 44.63  ? 78  LEU A O     1 
ATOM   364  C CB    . LEU A 1 78  ? 156.477 160.348 166.456 1.00 29.60  ? 78  LEU A CB    1 
ATOM   365  C CG    . LEU A 1 78  ? 155.654 161.618 166.258 1.00 29.46  ? 78  LEU A CG    1 
ATOM   366  C CD1   . LEU A 1 78  ? 154.868 161.945 167.507 1.00 31.50  ? 78  LEU A CD1   1 
ATOM   367  C CD2   . LEU A 1 78  ? 156.548 162.763 165.869 1.00 38.60  ? 78  LEU A CD2   1 
ATOM   368  N N     . SER A 1 79  ? 159.365 159.041 166.189 1.00 37.71  ? 79  SER A N     1 
ATOM   369  C CA    . SER A 1 79  ? 160.315 158.053 166.674 1.00 41.93  ? 79  SER A CA    1 
ATOM   370  C C     . SER A 1 79  ? 160.671 158.385 168.117 1.00 44.66  ? 79  SER A C     1 
ATOM   371  O O     . SER A 1 79  ? 160.217 159.386 168.677 1.00 45.10  ? 79  SER A O     1 
ATOM   372  C CB    . SER A 1 79  ? 161.574 158.013 165.797 1.00 48.73  ? 79  SER A CB    1 
ATOM   373  O OG    . SER A 1 79  ? 162.409 156.918 166.134 1.00 57.18  ? 79  SER A OG    1 
ATOM   374  N N     . GLU A 1 80  ? 161.485 157.523 168.729 1.00 49.03  ? 80  GLU A N     1 
ATOM   375  C CA    . GLU A 1 80  ? 161.923 157.760 170.100 1.00 51.26  ? 80  GLU A CA    1 
ATOM   376  C C     . GLU A 1 80  ? 162.834 158.974 170.211 1.00 51.61  ? 80  GLU A C     1 
ATOM   377  O O     . GLU A 1 80  ? 163.057 159.468 171.322 1.00 50.20  ? 80  GLU A O     1 
ATOM   378  C CB    . GLU A 1 80  ? 162.630 156.519 170.648 1.00 56.95  ? 80  GLU A CB    1 
ATOM   379  C CG    . GLU A 1 80  ? 163.737 155.977 169.753 1.00 68.85  ? 80  GLU A CG    1 
ATOM   380  C CD    . GLU A 1 80  ? 165.070 156.662 169.981 1.00 77.81  ? 80  GLU A CD    1 
ATOM   381  O OE1   . GLU A 1 80  ? 165.259 157.255 171.064 1.00 78.50  ? 80  GLU A OE1   1 
ATOM   382  O OE2   . GLU A 1 80  ? 165.930 156.607 169.077 1.00 79.20  ? 80  GLU A OE2   1 
ATOM   383  N N     . GLN A 1 81  ? 163.362 159.459 169.087 1.00 46.29  ? 81  GLN A N     1 
ATOM   384  C CA    . GLN A 1 81  ? 164.271 160.598 169.115 1.00 50.73  ? 81  GLN A CA    1 
ATOM   385  C C     . GLN A 1 81  ? 163.553 161.895 169.471 1.00 53.44  ? 81  GLN A C     1 
ATOM   386  O O     . GLN A 1 81  ? 164.158 162.788 170.076 1.00 58.94  ? 81  GLN A O     1 
ATOM   387  C CB    . GLN A 1 81  ? 164.978 160.724 167.765 1.00 53.25  ? 81  GLN A CB    1 
ATOM   388  C CG    . GLN A 1 81  ? 166.003 161.849 167.684 1.00 60.54  ? 81  GLN A CG    1 
ATOM   389  C CD    . GLN A 1 81  ? 167.167 161.662 168.641 1.00 60.53  ? 81  GLN A CD    1 
ATOM   390  O OE1   . GLN A 1 81  ? 167.420 160.560 169.126 1.00 61.64  ? 81  GLN A OE1   1 
ATOM   391  N NE2   . GLN A 1 81  ? 167.883 162.745 168.916 1.00 58.56  ? 81  GLN A NE2   1 
ATOM   392  N N     . ASP A 1 82  ? 162.272 162.021 169.121 1.00 44.35  ? 82  ASP A N     1 
ATOM   393  C CA    . ASP A 1 82  ? 161.531 163.257 169.331 1.00 40.72  ? 82  ASP A CA    1 
ATOM   394  C C     . ASP A 1 82  ? 160.701 163.239 170.609 1.00 36.89  ? 82  ASP A C     1 
ATOM   395  O O     . ASP A 1 82  ? 159.679 163.930 170.687 1.00 36.50  ? 82  ASP A O     1 
ATOM   396  C CB    . ASP A 1 82  ? 160.641 163.556 168.124 1.00 41.13  ? 82  ASP A CB    1 
ATOM   397  C CG    . ASP A 1 82  ? 159.586 162.497 167.896 1.00 47.54  ? 82  ASP A CG    1 
ATOM   398  O OD1   . ASP A 1 82  ? 158.551 162.515 168.595 1.00 48.91  ? 82  ASP A OD1   1 
ATOM   399  O OD2   . ASP A 1 82  ? 159.790 161.647 167.008 1.00 47.92  ? 82  ASP A OD2   1 
ATOM   400  N N     . LEU A 1 83  ? 161.112 162.463 171.608 1.00 37.17  ? 83  LEU A N     1 
ATOM   401  C CA    . LEU A 1 83  ? 160.424 162.479 172.891 1.00 35.49  ? 83  LEU A CA    1 
ATOM   402  C C     . LEU A 1 83  ? 160.536 163.857 173.530 1.00 30.34  ? 83  LEU A C     1 
ATOM   403  O O     . LEU A 1 83  ? 161.609 164.465 173.554 1.00 33.09  ? 83  LEU A O     1 
ATOM   404  C CB    . LEU A 1 83  ? 161.004 161.409 173.817 1.00 38.11  ? 83  LEU A CB    1 
ATOM   405  C CG    . LEU A 1 83  ? 160.261 160.072 173.894 1.00 31.73  ? 83  LEU A CG    1 
ATOM   406  C CD1   . LEU A 1 83  ? 158.999 160.208 174.720 1.00 28.10  ? 83  LEU A CD1   1 
ATOM   407  C CD2   . LEU A 1 83  ? 159.925 159.553 172.510 1.00 34.72  ? 83  LEU A CD2   1 
ATOM   408  N N     . GLY A 1 84  ? 159.416 164.347 174.055 1.00 27.87  ? 84  GLY A N     1 
ATOM   409  C CA    . GLY A 1 84  ? 159.320 165.690 174.576 1.00 32.63  ? 84  GLY A CA    1 
ATOM   410  C C     . GLY A 1 84  ? 158.950 166.733 173.540 1.00 35.85  ? 84  GLY A C     1 
ATOM   411  O O     . GLY A 1 84  ? 158.232 167.685 173.860 1.00 34.65  ? 84  GLY A O     1 
ATOM   412  N N     . ARG A 1 85  ? 159.425 166.576 172.309 1.00 36.49  ? 85  ARG A N     1 
ATOM   413  C CA    . ARG A 1 85  ? 159.055 167.482 171.233 1.00 30.95  ? 85  ARG A CA    1 
ATOM   414  C C     . ARG A 1 85  ? 157.582 167.313 170.885 1.00 30.37  ? 85  ARG A C     1 
ATOM   415  O O     . ARG A 1 85  ? 157.005 166.233 171.031 1.00 35.61  ? 85  ARG A O     1 
ATOM   416  C CB    . ARG A 1 85  ? 159.929 167.226 170.003 1.00 41.34  ? 85  ARG A CB    1 
ATOM   417  C CG    . ARG A 1 85  ? 159.596 168.079 168.788 1.00 47.27  ? 85  ARG A CG    1 
ATOM   418  C CD    . ARG A 1 85  ? 160.633 167.915 167.689 1.00 51.97  ? 85  ARG A CD    1 
ATOM   419  N NE    . ARG A 1 85  ? 160.200 168.517 166.434 1.00 57.39  ? 85  ARG A NE    1 
ATOM   420  C CZ    . ARG A 1 85  ? 160.267 169.812 166.159 1.00 58.01  ? 85  ARG A CZ    1 
ATOM   421  N NH1   . ARG A 1 85  ? 160.731 170.683 167.041 1.00 51.70  ? 85  ARG A NH1   1 
ATOM   422  N NH2   . ARG A 1 85  ? 159.857 170.246 164.971 1.00 58.55  ? 85  ARG A NH2   1 
ATOM   423  N N     . SER A 1 86  ? 156.970 168.404 170.435 1.00 30.86  ? 86  SER A N     1 
ATOM   424  C CA    . SER A 1 86  ? 155.574 168.365 170.028 1.00 38.14  ? 86  SER A CA    1 
ATOM   425  C C     . SER A 1 86  ? 155.375 167.362 168.901 1.00 36.00  ? 86  SER A C     1 
ATOM   426  O O     . SER A 1 86  ? 156.222 167.220 168.015 1.00 42.33  ? 86  SER A O     1 
ATOM   427  C CB    . SER A 1 86  ? 155.117 169.755 169.584 1.00 52.81  ? 86  SER A CB    1 
ATOM   428  O OG    . SER A 1 86  ? 153.816 169.713 169.028 1.00 52.73  ? 86  SER A OG    1 
ATOM   429  N N     . ARG A 1 87  ? 154.248 166.651 168.946 1.00 31.76  ? 87  ARG A N     1 
ATOM   430  C CA    . ARG A 1 87  ? 153.957 165.658 167.919 1.00 35.78  ? 87  ARG A CA    1 
ATOM   431  C C     . ARG A 1 87  ? 153.786 166.312 166.553 1.00 42.16  ? 87  ARG A C     1 
ATOM   432  O O     . ARG A 1 87  ? 154.344 165.843 165.554 1.00 45.71  ? 87  ARG A O     1 
ATOM   433  C CB    . ARG A 1 87  ? 152.704 164.867 168.294 1.00 37.70  ? 87  ARG A CB    1 
ATOM   434  C CG    . ARG A 1 87  ? 152.810 164.097 169.597 1.00 35.26  ? 87  ARG A CG    1 
ATOM   435  C CD    . ARG A 1 87  ? 151.547 163.295 169.862 1.00 37.21  ? 87  ARG A CD    1 
ATOM   436  N NE    . ARG A 1 87  ? 150.983 163.589 171.173 1.00 40.08  ? 87  ARG A NE    1 
ATOM   437  C CZ    . ARG A 1 87  ? 149.774 163.219 171.570 1.00 40.37  ? 87  ARG A CZ    1 
ATOM   438  N NH1   . ARG A 1 87  ? 148.964 162.539 170.778 1.00 43.81  ? 87  ARG A NH1   1 
ATOM   439  N NH2   . ARG A 1 87  ? 149.366 163.545 172.792 1.00 40.65  ? 87  ARG A NH2   1 
ATOM   440  N N     . ALA A 1 88  ? 153.017 167.401 166.491 1.00 40.02  ? 88  ALA A N     1 
ATOM   441  C CA    . ALA A 1 88  ? 152.746 168.048 165.211 1.00 36.10  ? 88  ALA A CA    1 
ATOM   442  C C     . ALA A 1 88  ? 154.014 168.628 164.596 1.00 35.44  ? 88  ALA A C     1 
ATOM   443  O O     . ALA A 1 88  ? 154.250 168.484 163.390 1.00 40.92  ? 88  ALA A O     1 
ATOM   444  C CB    . ALA A 1 88  ? 151.692 169.138 165.388 1.00 36.93  ? 88  ALA A CB    1 
ATOM   445  N N     . GLU A 1 89  ? 154.841 169.287 165.409 1.00 32.03  ? 89  GLU A N     1 
ATOM   446  C CA    . GLU A 1 89  ? 156.051 169.908 164.883 1.00 37.63  ? 89  GLU A CA    1 
ATOM   447  C C     . GLU A 1 89  ? 157.014 168.866 164.333 1.00 44.72  ? 89  GLU A C     1 
ATOM   448  O O     . GLU A 1 89  ? 157.637 169.075 163.286 1.00 47.80  ? 89  GLU A O     1 
ATOM   449  C CB    . GLU A 1 89  ? 156.723 170.747 165.968 1.00 41.41  ? 89  GLU A CB    1 
ATOM   450  C CG    . GLU A 1 89  ? 155.928 171.977 166.375 1.00 52.44  ? 89  GLU A CG    1 
ATOM   451  C CD    . GLU A 1 89  ? 156.599 172.766 167.481 1.00 64.00  ? 89  GLU A CD    1 
ATOM   452  O OE1   . GLU A 1 89  ? 157.357 172.162 168.269 1.00 57.79  ? 89  GLU A OE1   1 
ATOM   453  O OE2   . GLU A 1 89  ? 156.373 173.992 167.560 1.00 67.13  ? 89  GLU A OE2   1 
ATOM   454  N N     . ALA A 1 90  ? 157.150 167.734 165.026 1.00 46.25  ? 90  ALA A N     1 
ATOM   455  C CA    . ALA A 1 90  ? 158.055 166.692 164.558 1.00 42.63  ? 90  ALA A CA    1 
ATOM   456  C C     . ALA A 1 90  ? 157.480 165.932 163.370 1.00 40.53  ? 90  ALA A C     1 
ATOM   457  O O     . ALA A 1 90  ? 158.239 165.453 162.520 1.00 47.74  ? 90  ALA A O     1 
ATOM   458  C CB    . ALA A 1 90  ? 158.383 165.736 165.702 1.00 36.15  ? 90  ALA A CB    1 
ATOM   459  N N     . SER A 1 91  ? 156.155 165.811 163.290 1.00 34.64  ? 91  SER A N     1 
ATOM   460  C CA    . SER A 1 91  ? 155.514 165.072 162.210 1.00 35.96  ? 91  SER A CA    1 
ATOM   461  C C     . SER A 1 91  ? 155.288 165.906 160.955 1.00 37.81  ? 91  SER A C     1 
ATOM   462  O O     . SER A 1 91  ? 154.956 165.337 159.906 1.00 42.18  ? 91  SER A O     1 
ATOM   463  C CB    . SER A 1 91  ? 154.177 164.510 162.693 1.00 38.68  ? 91  SER A CB    1 
ATOM   464  O OG    . SER A 1 91  ? 153.265 165.551 162.992 1.00 40.82  ? 91  SER A OG    1 
ATOM   465  N N     . GLN A 1 92  ? 155.443 167.230 161.040 1.00 38.20  ? 92  GLN A N     1 
ATOM   466  C CA    . GLN A 1 92  ? 155.209 168.079 159.875 1.00 34.06  ? 92  GLN A CA    1 
ATOM   467  C C     . GLN A 1 92  ? 156.157 167.738 158.732 1.00 37.95  ? 92  GLN A C     1 
ATOM   468  O O     . GLN A 1 92  ? 155.739 167.678 157.570 1.00 41.71  ? 92  GLN A O     1 
ATOM   469  C CB    . GLN A 1 92  ? 155.345 169.549 160.269 1.00 27.88  ? 92  GLN A CB    1 
ATOM   470  C CG    . GLN A 1 92  ? 155.052 170.530 159.152 1.00 31.21  ? 92  GLN A CG    1 
ATOM   471  C CD    . GLN A 1 92  ? 156.303 170.992 158.439 1.00 36.98  ? 92  GLN A CD    1 
ATOM   472  O OE1   . GLN A 1 92  ? 157.417 170.664 158.844 1.00 43.85  ? 92  GLN A OE1   1 
ATOM   473  N NE2   . GLN A 1 92  ? 156.126 171.758 157.370 1.00 35.73  ? 92  GLN A NE2   1 
ATOM   474  N N     . LYS A 1 93  ? 157.438 167.523 159.037 1.00 37.34  ? 93  LYS A N     1 
ATOM   475  C CA    . LYS A 1 93  ? 158.402 167.196 157.990 1.00 36.00  ? 93  LYS A CA    1 
ATOM   476  C C     . LYS A 1 93  ? 158.069 165.868 157.326 1.00 35.35  ? 93  LYS A C     1 
ATOM   477  O O     . LYS A 1 93  ? 158.122 165.745 156.094 1.00 38.79  ? 93  LYS A O     1 
ATOM   478  C CB    . LYS A 1 93  ? 159.813 167.164 158.575 1.00 39.24  ? 93  LYS A CB    1 
ATOM   479  C CG    . LYS A 1 93  ? 160.822 166.407 157.730 1.00 43.20  ? 93  LYS A CG    1 
ATOM   480  C CD    . LYS A 1 93  ? 162.179 166.361 158.404 1.00 44.47  ? 93  LYS A CD    1 
ATOM   481  C CE    . LYS A 1 93  ? 162.804 167.741 158.472 1.00 58.39  ? 93  LYS A CE    1 
ATOM   482  N NZ    . LYS A 1 93  ? 162.994 168.323 157.116 1.00 58.93  ? 93  LYS A NZ    1 
ATOM   483  N N     . LEU A 1 94  ? 157.727 164.859 158.129 1.00 36.21  ? 94  LEU A N     1 
ATOM   484  C CA    . LEU A 1 94  ? 157.414 163.550 157.573 1.00 37.41  ? 94  LEU A CA    1 
ATOM   485  C C     . LEU A 1 94  ? 156.139 163.589 156.748 1.00 33.79  ? 94  LEU A C     1 
ATOM   486  O O     . LEU A 1 94  ? 156.009 162.833 155.779 1.00 40.81  ? 94  LEU A O     1 
ATOM   487  C CB    . LEU A 1 94  ? 157.302 162.512 158.689 1.00 38.20  ? 94  LEU A CB    1 
ATOM   488  C CG    . LEU A 1 94  ? 158.598 161.898 159.228 1.00 35.28  ? 94  LEU A CG    1 
ATOM   489  C CD1   . LEU A 1 94  ? 159.409 161.296 158.094 1.00 37.67  ? 94  LEU A CD1   1 
ATOM   490  C CD2   . LEU A 1 94  ? 159.425 162.901 160.023 1.00 33.67  ? 94  LEU A CD2   1 
ATOM   491  N N     . LEU A 1 95  ? 155.193 164.455 157.109 1.00 32.39  ? 95  LEU A N     1 
ATOM   492  C CA    . LEU A 1 95  ? 154.004 164.623 156.279 1.00 35.19  ? 95  LEU A CA    1 
ATOM   493  C C     . LEU A 1 95  ? 154.329 165.354 154.984 1.00 39.74  ? 95  LEU A C     1 
ATOM   494  O O     . LEU A 1 95  ? 153.791 165.018 153.923 1.00 43.15  ? 95  LEU A O     1 
ATOM   495  C CB    . LEU A 1 95  ? 152.925 165.371 157.051 1.00 31.58  ? 95  LEU A CB    1 
ATOM   496  C CG    . LEU A 1 95  ? 152.081 164.510 157.976 1.00 27.40  ? 95  LEU A CG    1 
ATOM   497  C CD1   . LEU A 1 95  ? 151.166 165.381 158.789 1.00 27.64  ? 95  LEU A CD1   1 
ATOM   498  C CD2   . LEU A 1 95  ? 151.290 163.505 157.164 1.00 32.86  ? 95  LEU A CD2   1 
ATOM   499  N N     . ALA A 1 96  ? 155.197 166.365 155.055 1.00 39.01  ? 96  ALA A N     1 
ATOM   500  C CA    . ALA A 1 96  ? 155.565 167.109 153.856 1.00 36.71  ? 96  ALA A CA    1 
ATOM   501  C C     . ALA A 1 96  ? 156.279 166.215 152.855 1.00 40.36  ? 96  ALA A C     1 
ATOM   502  O O     . ALA A 1 96  ? 156.060 166.328 151.643 1.00 48.65  ? 96  ALA A O     1 
ATOM   503  C CB    . ALA A 1 96  ? 156.443 168.303 154.226 1.00 37.36  ? 96  ALA A CB    1 
ATOM   504  N N     . GLU A 1 97  ? 157.139 165.319 153.341 1.00 39.35  ? 97  GLU A N     1 
ATOM   505  C CA    . GLU A 1 97  ? 157.876 164.446 152.434 1.00 39.16  ? 97  GLU A CA    1 
ATOM   506  C C     . GLU A 1 97  ? 156.967 163.485 151.678 1.00 39.62  ? 97  GLU A C     1 
ATOM   507  O O     . GLU A 1 97  ? 157.361 162.994 150.616 1.00 47.63  ? 97  GLU A O     1 
ATOM   508  C CB    . GLU A 1 97  ? 158.934 163.655 153.200 1.00 46.20  ? 97  GLU A CB    1 
ATOM   509  C CG    . GLU A 1 97  ? 160.075 164.495 153.733 1.00 52.88  ? 97  GLU A CG    1 
ATOM   510  C CD    . GLU A 1 97  ? 161.095 163.667 154.484 1.00 59.35  ? 97  GLU A CD    1 
ATOM   511  O OE1   . GLU A 1 97  ? 160.891 162.441 154.606 1.00 57.96  ? 97  GLU A OE1   1 
ATOM   512  O OE2   . GLU A 1 97  ? 162.101 164.240 154.949 1.00 62.27  ? 97  GLU A OE2   1 
ATOM   513  N N     . LEU A 1 98  ? 155.769 163.204 152.197 1.00 37.85  ? 98  LEU A N     1 
ATOM   514  C CA    . LEU A 1 98  ? 154.869 162.280 151.514 1.00 44.85  ? 98  LEU A CA    1 
ATOM   515  C C     . LEU A 1 98  ? 154.317 162.871 150.223 1.00 51.40  ? 98  LEU A C     1 
ATOM   516  O O     . LEU A 1 98  ? 154.123 162.140 149.244 1.00 53.94  ? 98  LEU A O     1 
ATOM   517  C CB    . LEU A 1 98  ? 153.720 161.884 152.438 1.00 46.01  ? 98  LEU A CB    1 
ATOM   518  C CG    . LEU A 1 98  ? 154.109 161.213 153.752 1.00 47.20  ? 98  LEU A CG    1 
ATOM   519  C CD1   . LEU A 1 98  ? 152.870 160.720 154.482 1.00 47.23  ? 98  LEU A CD1   1 
ATOM   520  C CD2   . LEU A 1 98  ? 155.082 160.075 153.504 1.00 48.92  ? 98  LEU A CD2   1 
ATOM   521  N N     . ASN A 1 99  ? 154.062 164.178 150.199 1.00 50.36  ? 99  ASN A N     1 
ATOM   522  C CA    . ASN A 1 99  ? 153.534 164.844 149.010 1.00 48.92  ? 99  ASN A CA    1 
ATOM   523  C C     . ASN A 1 99  ? 154.041 166.278 149.024 1.00 51.71  ? 99  ASN A C     1 
ATOM   524  O O     . ASN A 1 99  ? 153.586 167.090 149.836 1.00 54.37  ? 99  ASN A O     1 
ATOM   525  C CB    . ASN A 1 99  ? 152.008 164.801 148.982 1.00 42.07  ? 99  ASN A CB    1 
ATOM   526  C CG    . ASN A 1 99  ? 151.430 165.252 147.654 1.00 49.94  ? 99  ASN A CG    1 
ATOM   527  O OD1   . ASN A 1 99  ? 152.149 165.725 146.775 1.00 59.81  ? 99  ASN A OD1   1 
ATOM   528  N ND2   . ASN A 1 99  ? 150.119 165.117 147.507 1.00 47.10  ? 99  ASN A ND2   1 
ATOM   529  N N     . GLY A 1 100 ? 154.980 166.587 148.131 1.00 49.70  ? 100 GLY A N     1 
ATOM   530  C CA    . GLY A 1 100 ? 155.539 167.923 148.059 1.00 50.05  ? 100 GLY A CA    1 
ATOM   531  C C     . GLY A 1 100 ? 154.575 168.984 147.574 1.00 56.99  ? 100 GLY A C     1 
ATOM   532  O O     . GLY A 1 100 ? 154.882 170.175 147.695 1.00 56.91  ? 100 GLY A O     1 
ATOM   533  N N     . ALA A 1 101 ? 153.427 168.585 147.033 1.00 53.06  ? 101 ALA A N     1 
ATOM   534  C CA    . ALA A 1 101 ? 152.427 169.512 146.525 1.00 54.48  ? 101 ALA A CA    1 
ATOM   535  C C     . ALA A 1 101 ? 151.366 169.858 147.559 1.00 55.24  ? 101 ALA A C     1 
ATOM   536  O O     . ALA A 1 101 ? 150.328 170.420 147.197 1.00 56.05  ? 101 ALA A O     1 
ATOM   537  C CB    . ALA A 1 101 ? 151.761 168.936 145.273 1.00 58.39  ? 101 ALA A CB    1 
ATOM   538  N N     . VAL A 1 102 ? 151.596 169.524 148.826 1.00 57.21  ? 102 VAL A N     1 
ATOM   539  C CA    . VAL A 1 102 ? 150.661 169.800 149.910 1.00 51.71  ? 102 VAL A CA    1 
ATOM   540  C C     . VAL A 1 102 ? 151.349 170.710 150.916 1.00 48.42  ? 102 VAL A C     1 
ATOM   541  O O     . VAL A 1 102 ? 152.472 170.428 151.348 1.00 47.12  ? 102 VAL A O     1 
ATOM   542  C CB    . VAL A 1 102 ? 150.177 168.504 150.586 1.00 48.42  ? 102 VAL A CB    1 
ATOM   543  C CG1   . VAL A 1 102 ? 149.405 168.823 151.854 1.00 48.57  ? 102 VAL A CG1   1 
ATOM   544  C CG2   . VAL A 1 102 ? 149.319 167.699 149.628 1.00 49.89  ? 102 VAL A CG2   1 
ATOM   545  N N     . GLN A 1 103 ? 150.678 171.801 151.279 1.00 50.01  ? 103 GLN A N     1 
ATOM   546  C CA    . GLN A 1 103 ? 151.194 172.755 152.259 1.00 49.83  ? 103 GLN A CA    1 
ATOM   547  C C     . GLN A 1 103 ? 150.868 172.240 153.654 1.00 51.00  ? 103 GLN A C     1 
ATOM   548  O O     . GLN A 1 103 ? 149.810 172.524 154.217 1.00 48.20  ? 103 GLN A O     1 
ATOM   549  C CB    . GLN A 1 103 ? 150.608 174.144 152.028 1.00 42.89  ? 103 GLN A CB    1 
ATOM   550  C CG    . GLN A 1 103 ? 151.248 174.920 150.884 1.00 50.74  ? 103 GLN A CG    1 
ATOM   551  C CD    . GLN A 1 103 ? 150.871 174.378 149.519 1.00 60.99  ? 103 GLN A CD    1 
ATOM   552  O OE1   . GLN A 1 103 ? 149.716 174.464 149.101 1.00 63.62  ? 103 GLN A OE1   1 
ATOM   553  N NE2   . GLN A 1 103 ? 151.846 173.815 148.815 1.00 57.82  ? 103 GLN A NE2   1 
ATOM   554  N N     . VAL A 1 104 ? 151.792 171.468 154.219 1.00 49.67  ? 104 VAL A N     1 
ATOM   555  C CA    . VAL A 1 104 ? 151.659 170.961 155.579 1.00 37.88  ? 104 VAL A CA    1 
ATOM   556  C C     . VAL A 1 104 ? 152.246 171.986 156.538 1.00 35.08  ? 104 VAL A C     1 
ATOM   557  O O     . VAL A 1 104 ? 153.410 172.381 156.404 1.00 36.87  ? 104 VAL A O     1 
ATOM   558  C CB    . VAL A 1 104 ? 152.355 169.599 155.732 1.00 34.91  ? 104 VAL A CB    1 
ATOM   559  C CG1   . VAL A 1 104 ? 152.188 169.080 157.145 1.00 35.00  ? 104 VAL A CG1   1 
ATOM   560  C CG2   . VAL A 1 104 ? 151.798 168.606 154.728 1.00 40.42  ? 104 VAL A CG2   1 
ATOM   561  N N     . SER A 1 105 ? 151.442 172.414 157.509 1.00 34.29  ? 105 SER A N     1 
ATOM   562  C CA    . SER A 1 105 ? 151.830 173.456 158.447 1.00 28.85  ? 105 SER A CA    1 
ATOM   563  C C     . SER A 1 105 ? 151.461 173.027 159.859 1.00 28.58  ? 105 SER A C     1 
ATOM   564  O O     . SER A 1 105 ? 150.744 172.046 160.067 1.00 35.39  ? 105 SER A O     1 
ATOM   565  C CB    . SER A 1 105 ? 151.165 174.792 158.102 1.00 30.24  ? 105 SER A CB    1 
ATOM   566  O OG    . SER A 1 105 ? 149.759 174.650 158.023 1.00 34.31  ? 105 SER A OG    1 
ATOM   567  N N     . VAL A 1 106 ? 151.969 173.774 160.836 1.00 26.75  ? 106 VAL A N     1 
ATOM   568  C CA    . VAL A 1 106 ? 151.690 173.538 162.246 1.00 27.57  ? 106 VAL A CA    1 
ATOM   569  C C     . VAL A 1 106 ? 151.193 174.832 162.872 1.00 35.62  ? 106 VAL A C     1 
ATOM   570  O O     . VAL A 1 106 ? 151.757 175.905 162.631 1.00 45.05  ? 106 VAL A O     1 
ATOM   571  C CB    . VAL A 1 106 ? 152.937 173.027 162.997 1.00 29.30  ? 106 VAL A CB    1 
ATOM   572  C CG1   . VAL A 1 106 ? 152.601 172.744 164.452 1.00 35.21  ? 106 VAL A CG1   1 
ATOM   573  C CG2   . VAL A 1 106 ? 153.494 171.793 162.324 1.00 31.23  ? 106 VAL A CG2   1 
ATOM   574  N N     . TYR A 1 107 ? 150.136 174.733 163.674 1.00 32.86  ? 107 TYR A N     1 
ATOM   575  C CA    . TYR A 1 107 ? 149.644 175.849 164.471 1.00 37.06  ? 107 TYR A CA    1 
ATOM   576  C C     . TYR A 1 107 ? 149.940 175.556 165.934 1.00 47.05  ? 107 TYR A C     1 
ATOM   577  O O     . TYR A 1 107 ? 149.496 174.534 166.468 1.00 50.37  ? 107 TYR A O     1 
ATOM   578  C CB    . TYR A 1 107 ? 148.148 176.069 164.258 1.00 38.46  ? 107 TYR A CB    1 
ATOM   579  C CG    . TYR A 1 107 ? 147.662 177.407 164.768 1.00 56.79  ? 107 TYR A CG    1 
ATOM   580  C CD1   . TYR A 1 107 ? 147.848 178.564 164.022 1.00 60.15  ? 107 TYR A CD1   1 
ATOM   581  C CD2   . TYR A 1 107 ? 147.026 177.517 165.997 1.00 56.32  ? 107 TYR A CD2   1 
ATOM   582  C CE1   . TYR A 1 107 ? 147.409 179.792 164.483 1.00 60.94  ? 107 TYR A CE1   1 
ATOM   583  C CE2   . TYR A 1 107 ? 146.581 178.741 166.464 1.00 55.28  ? 107 TYR A CE2   1 
ATOM   584  C CZ    . TYR A 1 107 ? 146.777 179.874 165.704 1.00 60.55  ? 107 TYR A CZ    1 
ATOM   585  O OH    . TYR A 1 107 ? 146.338 181.093 166.167 1.00 68.39  ? 107 TYR A OH    1 
ATOM   586  N N     . THR A 1 108 ? 150.689 176.448 166.577 1.00 47.92  ? 108 THR A N     1 
ATOM   587  C CA    . THR A 1 108 ? 151.132 176.235 167.948 1.00 49.55  ? 108 THR A CA    1 
ATOM   588  C C     . THR A 1 108 ? 150.198 176.842 168.985 1.00 53.79  ? 108 THR A C     1 
ATOM   589  O O     . THR A 1 108 ? 150.418 176.644 170.184 1.00 51.74  ? 108 THR A O     1 
ATOM   590  C CB    . THR A 1 108 ? 152.541 176.803 168.137 1.00 51.76  ? 108 THR A CB    1 
ATOM   591  O OG1   . THR A 1 108 ? 152.515 178.223 167.946 1.00 57.30  ? 108 THR A OG1   1 
ATOM   592  C CG2   . THR A 1 108 ? 153.500 176.182 167.136 1.00 50.13  ? 108 THR A CG2   1 
ATOM   593  N N     . GLY A 1 109 ? 149.165 177.567 168.563 1.00 57.17  ? 109 GLY A N     1 
ATOM   594  C CA    . GLY A 1 109 ? 148.267 178.235 169.480 1.00 61.01  ? 109 GLY A CA    1 
ATOM   595  C C     . GLY A 1 109 ? 147.040 177.404 169.805 1.00 59.78  ? 109 GLY A C     1 
ATOM   596  O O     . GLY A 1 109 ? 146.961 176.208 169.521 1.00 58.12  ? 109 GLY A O     1 
ATOM   597  N N     . ASP A 1 110 ? 146.066 178.067 170.418 1.00 57.06  ? 110 ASP A N     1 
ATOM   598  C CA    . ASP A 1 110 ? 144.817 177.432 170.804 1.00 57.26  ? 110 ASP A CA    1 
ATOM   599  C C     . ASP A 1 110 ? 143.840 177.422 169.633 1.00 54.08  ? 110 ASP A C     1 
ATOM   600  O O     . ASP A 1 110 ? 143.966 178.193 168.679 1.00 58.52  ? 110 ASP A O     1 
ATOM   601  C CB    . ASP A 1 110 ? 144.198 178.154 172.003 1.00 67.45  ? 110 ASP A CB    1 
ATOM   602  C CG    . ASP A 1 110 ? 143.152 177.317 172.715 1.00 76.00  ? 110 ASP A CG    1 
ATOM   603  O OD1   . ASP A 1 110 ? 143.141 176.083 172.525 1.00 71.53  ? 110 ASP A OD1   1 
ATOM   604  O OD2   . ASP A 1 110 ? 142.338 177.896 173.464 1.00 80.28  ? 110 ASP A OD2   1 
ATOM   605  N N     . ILE A 1 111 ? 142.855 176.531 169.718 1.00 51.04  ? 111 ILE A N     1 
ATOM   606  C CA    . ILE A 1 111 ? 141.828 176.403 168.683 1.00 56.81  ? 111 ILE A CA    1 
ATOM   607  C C     . ILE A 1 111 ? 140.736 177.412 169.027 1.00 53.16  ? 111 ILE A C     1 
ATOM   608  O O     . ILE A 1 111 ? 139.758 177.103 169.706 1.00 51.01  ? 111 ILE A O     1 
ATOM   609  C CB    . ILE A 1 111 ? 141.291 174.978 168.581 1.00 60.17  ? 111 ILE A CB    1 
ATOM   610  C CG1   . ILE A 1 111 ? 142.443 173.980 168.492 1.00 52.79  ? 111 ILE A CG1   1 
ATOM   611  C CG2   . ILE A 1 111 ? 140.380 174.840 167.370 1.00 53.62  ? 111 ILE A CG2   1 
ATOM   612  C CD1   . ILE A 1 111 ? 141.994 172.543 168.427 1.00 44.59  ? 111 ILE A CD1   1 
ATOM   613  N N     . THR A 1 112 ? 140.909 178.637 168.546 1.00 52.08  ? 112 THR A N     1 
ATOM   614  C CA    . THR A 1 112 ? 139.934 179.695 168.737 1.00 50.09  ? 112 THR A CA    1 
ATOM   615  C C     . THR A 1 112 ? 139.034 179.793 167.507 1.00 51.93  ? 112 THR A C     1 
ATOM   616  O O     . THR A 1 112 ? 139.202 179.072 166.521 1.00 58.03  ? 112 THR A O     1 
ATOM   617  C CB    . THR A 1 112 ? 140.634 181.025 169.021 1.00 56.09  ? 112 THR A CB    1 
ATOM   618  O OG1   . THR A 1 112 ? 141.591 181.295 167.989 1.00 56.48  ? 112 THR A OG1   1 
ATOM   619  C CG2   . THR A 1 112 ? 141.346 180.974 170.362 1.00 56.55  ? 112 THR A CG2   1 
ATOM   620  N N     . LYS A 1 113 ? 138.055 180.696 167.576 1.00 44.28  ? 113 LYS A N     1 
ATOM   621  C CA    . LYS A 1 113 ? 137.147 180.888 166.450 1.00 47.71  ? 113 LYS A CA    1 
ATOM   622  C C     . LYS A 1 113 ? 137.870 181.470 165.239 1.00 60.91  ? 113 LYS A C     1 
ATOM   623  O O     . LYS A 1 113 ? 137.591 181.082 164.098 1.00 59.26  ? 113 LYS A O     1 
ATOM   624  C CB    . LYS A 1 113 ? 135.984 181.782 166.872 1.00 47.80  ? 113 LYS A CB    1 
ATOM   625  C CG    . LYS A 1 113 ? 135.230 182.410 165.722 1.00 58.30  ? 113 LYS A CG    1 
ATOM   626  C CD    . LYS A 1 113 ? 133.734 182.351 165.954 1.00 64.65  ? 113 LYS A CD    1 
ATOM   627  C CE    . LYS A 1 113 ? 133.353 182.845 167.339 1.00 63.04  ? 113 LYS A CE    1 
ATOM   628  N NZ    . LYS A 1 113 ? 131.894 182.683 167.587 1.00 60.99  ? 113 LYS A NZ    1 
ATOM   629  N N     . ASP A 1 114 ? 138.797 182.405 165.466 1.00 65.36  ? 114 ASP A N     1 
ATOM   630  C CA    . ASP A 1 114 ? 139.519 183.021 164.356 1.00 64.41  ? 114 ASP A CA    1 
ATOM   631  C C     . ASP A 1 114 ? 140.331 181.989 163.583 1.00 66.07  ? 114 ASP A C     1 
ATOM   632  O O     . ASP A 1 114 ? 140.345 181.997 162.347 1.00 67.99  ? 114 ASP A O     1 
ATOM   633  C CB    . ASP A 1 114 ? 140.429 184.135 164.874 1.00 72.10  ? 114 ASP A CB    1 
ATOM   634  C CG    . ASP A 1 114 ? 139.658 185.263 165.530 1.00 76.58  ? 114 ASP A CG    1 
ATOM   635  O OD1   . ASP A 1 114 ? 138.412 185.270 165.440 1.00 71.76  ? 114 ASP A OD1   1 
ATOM   636  O OD2   . ASP A 1 114 ? 140.299 186.145 166.140 1.00 78.11  ? 114 ASP A OD2   1 
ATOM   637  N N     . LEU A 1 115 ? 141.022 181.096 164.296 1.00 60.46  ? 115 LEU A N     1 
ATOM   638  C CA    . LEU A 1 115 ? 141.721 180.001 163.631 1.00 54.71  ? 115 LEU A CA    1 
ATOM   639  C C     . LEU A 1 115 ? 140.739 179.070 162.936 1.00 56.08  ? 115 LEU A C     1 
ATOM   640  O O     . LEU A 1 115 ? 141.001 178.593 161.826 1.00 59.59  ? 115 LEU A O     1 
ATOM   641  C CB    . LEU A 1 115 ? 142.564 179.225 164.641 1.00 53.80  ? 115 LEU A CB    1 
ATOM   642  C CG    . LEU A 1 115 ? 143.205 177.937 164.123 1.00 54.55  ? 115 LEU A CG    1 
ATOM   643  C CD1   . LEU A 1 115 ? 144.338 178.251 163.157 1.00 55.72  ? 115 LEU A CD1   1 
ATOM   644  C CD2   . LEU A 1 115 ? 143.689 177.071 165.271 1.00 50.92  ? 115 LEU A CD2   1 
ATOM   645  N N     . LEU A 1 116 ? 139.600 178.803 163.578 1.00 52.70  ? 116 LEU A N     1 
ATOM   646  C CA    . LEU A 1 116 ? 138.639 177.851 163.033 1.00 51.24  ? 116 LEU A CA    1 
ATOM   647  C C     . LEU A 1 116 ? 138.073 178.325 161.701 1.00 51.18  ? 116 LEU A C     1 
ATOM   648  O O     . LEU A 1 116 ? 137.888 177.524 160.778 1.00 52.11  ? 116 LEU A O     1 
ATOM   649  C CB    . LEU A 1 116 ? 137.513 177.619 164.040 1.00 53.63  ? 116 LEU A CB    1 
ATOM   650  C CG    . LEU A 1 116 ? 136.399 176.665 163.613 1.00 50.80  ? 116 LEU A CG    1 
ATOM   651  C CD1   . LEU A 1 116 ? 136.959 175.278 163.340 1.00 45.15  ? 116 LEU A CD1   1 
ATOM   652  C CD2   . LEU A 1 116 ? 135.315 176.614 164.674 1.00 43.22  ? 116 LEU A CD2   1 
ATOM   653  N N     . LEU A 1 117 ? 137.797 179.624 161.580 1.00 53.52  ? 117 LEU A N     1 
ATOM   654  C CA    . LEU A 1 117 ? 137.136 180.143 160.388 1.00 55.94  ? 117 LEU A CA    1 
ATOM   655  C C     . LEU A 1 117 ? 137.999 180.057 159.136 1.00 53.35  ? 117 LEU A C     1 
ATOM   656  O O     . LEU A 1 117 ? 137.477 180.256 158.034 1.00 59.56  ? 117 LEU A O     1 
ATOM   657  C CB    . LEU A 1 117 ? 136.703 181.593 160.615 1.00 62.38  ? 117 LEU A CB    1 
ATOM   658  C CG    . LEU A 1 117 ? 135.609 181.829 161.661 1.00 64.75  ? 117 LEU A CG    1 
ATOM   659  C CD1   . LEU A 1 117 ? 135.267 183.308 161.756 1.00 61.69  ? 117 LEU A CD1   1 
ATOM   660  C CD2   . LEU A 1 117 ? 134.365 181.004 161.353 1.00 57.93  ? 117 LEU A CD2   1 
ATOM   661  N N     . ASP A 1 118 ? 139.290 179.770 159.270 1.00 48.83  ? 118 ASP A N     1 
ATOM   662  C CA    . ASP A 1 118 ? 140.181 179.678 158.121 1.00 49.21  ? 118 ASP A CA    1 
ATOM   663  C C     . ASP A 1 118 ? 140.163 178.310 157.452 1.00 51.99  ? 118 ASP A C     1 
ATOM   664  O O     . ASP A 1 118 ? 140.870 178.122 156.456 1.00 50.73  ? 118 ASP A O     1 
ATOM   665  C CB    . ASP A 1 118 ? 141.614 180.024 158.537 1.00 55.72  ? 118 ASP A CB    1 
ATOM   666  C CG    . ASP A 1 118 ? 141.782 181.490 158.889 1.00 69.70  ? 118 ASP A CG    1 
ATOM   667  O OD1   . ASP A 1 118 ? 140.807 182.256 158.738 1.00 70.79  ? 118 ASP A OD1   1 
ATOM   668  O OD2   . ASP A 1 118 ? 142.890 181.876 159.315 1.00 77.28  ? 118 ASP A OD2   1 
ATOM   669  N N     . PHE A 1 119 ? 139.392 177.355 157.967 1.00 51.11  ? 119 PHE A N     1 
ATOM   670  C CA    . PHE A 1 119 ? 139.361 176.001 157.436 1.00 42.87  ? 119 PHE A CA    1 
ATOM   671  C C     . PHE A 1 119 ? 137.939 175.611 157.057 1.00 44.21  ? 119 PHE A C     1 
ATOM   672  O O     . PHE A 1 119 ? 136.966 176.116 157.623 1.00 48.92  ? 119 PHE A O     1 
ATOM   673  C CB    . PHE A 1 119 ? 139.917 174.998 158.449 1.00 35.54  ? 119 PHE A CB    1 
ATOM   674  C CG    . PHE A 1 119 ? 141.302 175.317 158.918 1.00 35.51  ? 119 PHE A CG    1 
ATOM   675  C CD1   . PHE A 1 119 ? 141.506 176.150 159.999 1.00 36.61  ? 119 PHE A CD1   1 
ATOM   676  C CD2   . PHE A 1 119 ? 142.403 174.780 158.278 1.00 39.74  ? 119 PHE A CD2   1 
ATOM   677  C CE1   . PHE A 1 119 ? 142.781 176.445 160.431 1.00 39.10  ? 119 PHE A CE1   1 
ATOM   678  C CE2   . PHE A 1 119 ? 143.680 175.070 158.708 1.00 38.05  ? 119 PHE A CE2   1 
ATOM   679  C CZ    . PHE A 1 119 ? 143.868 175.906 159.787 1.00 36.24  ? 119 PHE A CZ    1 
ATOM   680  N N     . GLN A 1 120 ? 137.829 174.712 156.079 1.00 38.50  ? 120 GLN A N     1 
ATOM   681  C CA    . GLN A 1 120 ? 136.533 174.190 155.666 1.00 38.36  ? 120 GLN A CA    1 
ATOM   682  C C     . GLN A 1 120 ? 136.148 172.924 156.415 1.00 38.99  ? 120 GLN A C     1 
ATOM   683  O O     . GLN A 1 120 ? 134.957 172.692 156.652 1.00 37.95  ? 120 GLN A O     1 
ATOM   684  C CB    . GLN A 1 120 ? 136.522 173.913 154.158 1.00 40.23  ? 120 GLN A CB    1 
ATOM   685  C CG    . GLN A 1 120 ? 136.238 175.131 153.282 1.00 50.18  ? 120 GLN A CG    1 
ATOM   686  C CD    . GLN A 1 120 ? 137.482 175.934 152.940 1.00 58.32  ? 120 GLN A CD    1 
ATOM   687  O OE1   . GLN A 1 120 ? 138.259 176.310 153.817 1.00 56.97  ? 120 GLN A OE1   1 
ATOM   688  N NE2   . GLN A 1 120 ? 137.674 176.202 151.654 1.00 51.79  ? 120 GLN A NE2   1 
ATOM   689  N N     . VAL A 1 121 ? 137.124 172.097 156.784 1.00 39.07  ? 121 VAL A N     1 
ATOM   690  C CA    . VAL A 1 121 ? 136.897 170.876 157.549 1.00 34.31  ? 121 VAL A CA    1 
ATOM   691  C C     . VAL A 1 121 ? 137.869 170.861 158.718 1.00 35.28  ? 121 VAL A C     1 
ATOM   692  O O     . VAL A 1 121 ? 139.060 171.137 158.539 1.00 36.87  ? 121 VAL A O     1 
ATOM   693  C CB    . VAL A 1 121 ? 137.078 169.614 156.683 1.00 36.85  ? 121 VAL A CB    1 
ATOM   694  C CG1   . VAL A 1 121 ? 136.735 168.369 157.483 1.00 37.83  ? 121 VAL A CG1   1 
ATOM   695  C CG2   . VAL A 1 121 ? 136.225 169.697 155.427 1.00 41.65  ? 121 VAL A CG2   1 
ATOM   696  N N     . VAL A 1 122 ? 137.366 170.541 159.909 1.00 34.03  ? 122 VAL A N     1 
ATOM   697  C CA    . VAL A 1 122 ? 138.175 170.450 161.119 1.00 27.67  ? 122 VAL A CA    1 
ATOM   698  C C     . VAL A 1 122 ? 137.982 169.069 161.730 1.00 29.22  ? 122 VAL A C     1 
ATOM   699  O O     . VAL A 1 122 ? 136.846 168.628 161.944 1.00 33.56  ? 122 VAL A O     1 
ATOM   700  C CB    . VAL A 1 122 ? 137.816 171.555 162.128 1.00 24.69  ? 122 VAL A CB    1 
ATOM   701  C CG1   . VAL A 1 122 ? 136.328 171.699 162.223 1.00 27.37  ? 122 VAL A CG1   1 
ATOM   702  C CG2   . VAL A 1 122 ? 138.407 171.248 163.491 1.00 28.29  ? 122 VAL A CG2   1 
ATOM   703  N N     . VAL A 1 123 ? 139.094 168.393 162.003 1.00 27.54  ? 123 VAL A N     1 
ATOM   704  C CA    . VAL A 1 123 ? 139.114 167.036 162.530 1.00 23.42  ? 123 VAL A CA    1 
ATOM   705  C C     . VAL A 1 123 ? 139.712 167.097 163.924 1.00 25.13  ? 123 VAL A C     1 
ATOM   706  O O     . VAL A 1 123 ? 140.777 167.692 164.120 1.00 28.55  ? 123 VAL A O     1 
ATOM   707  C CB    . VAL A 1 123 ? 139.924 166.095 161.626 1.00 24.59  ? 123 VAL A CB    1 
ATOM   708  C CG1   . VAL A 1 123 ? 139.837 164.660 162.126 1.00 28.73  ? 123 VAL A CG1   1 
ATOM   709  C CG2   . VAL A 1 123 ? 139.448 166.203 160.193 1.00 26.77  ? 123 VAL A CG2   1 
ATOM   710  N N     . LEU A 1 124 ? 139.014 166.522 164.895 1.00 25.03  ? 124 LEU A N     1 
ATOM   711  C CA    . LEU A 1 124 ? 139.516 166.395 166.253 1.00 25.30  ? 124 LEU A CA    1 
ATOM   712  C C     . LEU A 1 124 ? 139.811 164.935 166.558 1.00 29.67  ? 124 LEU A C     1 
ATOM   713  O O     . LEU A 1 124 ? 138.920 164.080 166.478 1.00 35.56  ? 124 LEU A O     1 
ATOM   714  C CB    . LEU A 1 124 ? 138.514 166.941 167.270 1.00 24.39  ? 124 LEU A CB    1 
ATOM   715  C CG    . LEU A 1 124 ? 138.197 168.431 167.199 1.00 27.69  ? 124 LEU A CG    1 
ATOM   716  C CD1   . LEU A 1 124 ? 137.506 168.878 168.466 1.00 29.05  ? 124 LEU A CD1   1 
ATOM   717  C CD2   . LEU A 1 124 ? 139.459 169.233 166.974 1.00 33.88  ? 124 LEU A CD2   1 
ATOM   718  N N     . THR A 1 125 ? 141.057 164.663 166.924 1.00 31.43  ? 125 THR A N     1 
ATOM   719  C CA    . THR A 1 125 ? 141.463 163.396 167.497 1.00 33.97  ? 125 THR A CA    1 
ATOM   720  C C     . THR A 1 125 ? 142.209 163.693 168.790 1.00 43.57  ? 125 THR A C     1 
ATOM   721  O O     . THR A 1 125 ? 142.752 164.785 168.972 1.00 44.67  ? 125 THR A O     1 
ATOM   722  C CB    . THR A 1 125 ? 142.356 162.596 166.537 1.00 30.16  ? 125 THR A CB    1 
ATOM   723  O OG1   . THR A 1 125 ? 143.659 163.186 166.490 1.00 37.67  ? 125 THR A OG1   1 
ATOM   724  C CG2   . THR A 1 125 ? 141.772 162.596 165.140 1.00 25.70  ? 125 THR A CG2   1 
ATOM   725  N N     . ALA A 1 126 ? 142.217 162.720 169.699 1.00 41.24  ? 126 ALA A N     1 
ATOM   726  C CA    . ALA A 1 126 ? 142.891 162.854 170.988 1.00 37.05  ? 126 ALA A CA    1 
ATOM   727  C C     . ALA A 1 126 ? 142.437 164.097 171.750 1.00 31.18  ? 126 ALA A C     1 
ATOM   728  O O     . ALA A 1 126 ? 143.205 164.671 172.527 1.00 34.85  ? 126 ALA A O     1 
ATOM   729  C CB    . ALA A 1 126 ? 144.416 162.856 170.817 1.00 40.14  ? 126 ALA A CB    1 
ATOM   730  N N     . SER A 1 127 ? 141.196 164.525 171.537 1.00 33.84  ? 127 SER A N     1 
ATOM   731  C CA    . SER A 1 127 ? 140.647 165.719 172.160 1.00 36.63  ? 127 SER A CA    1 
ATOM   732  C C     . SER A 1 127 ? 139.617 165.335 173.217 1.00 36.99  ? 127 SER A C     1 
ATOM   733  O O     . SER A 1 127 ? 138.848 164.387 173.035 1.00 35.97  ? 127 SER A O     1 
ATOM   734  C CB    . SER A 1 127 ? 140.012 166.636 171.111 1.00 32.38  ? 127 SER A CB    1 
ATOM   735  O OG    . SER A 1 127 ? 139.550 167.837 171.697 1.00 32.81  ? 127 SER A OG    1 
ATOM   736  N N     . ARG A 1 128 ? 139.624 166.064 174.329 1.00 40.54  ? 128 ARG A N     1 
ATOM   737  C CA    . ARG A 1 128 ? 138.690 165.806 175.415 1.00 39.50  ? 128 ARG A CA    1 
ATOM   738  C C     . ARG A 1 128 ? 137.281 166.240 175.015 1.00 38.83  ? 128 ARG A C     1 
ATOM   739  O O     . ARG A 1 128 ? 137.085 167.007 174.068 1.00 45.88  ? 128 ARG A O     1 
ATOM   740  C CB    . ARG A 1 128 ? 139.141 166.520 176.694 1.00 55.27  ? 128 ARG A CB    1 
ATOM   741  C CG    . ARG A 1 128 ? 140.205 165.773 177.518 1.00 70.16  ? 128 ARG A CG    1 
ATOM   742  C CD    . ARG A 1 128 ? 141.501 165.568 176.736 1.00 73.82  ? 128 ARG A CD    1 
ATOM   743  N NE    . ARG A 1 128 ? 142.570 164.970 177.527 1.00 83.02  ? 128 ARG A NE    1 
ATOM   744  C CZ    . ARG A 1 128 ? 143.738 164.581 177.031 1.00 95.35  ? 128 ARG A CZ    1 
ATOM   745  N NH1   . ARG A 1 128 ? 144.009 164.681 175.739 1.00 95.62  ? 128 ARG A NH1   1 
ATOM   746  N NH2   . ARG A 1 128 ? 144.657 164.078 177.851 1.00 93.17  ? 128 ARG A NH2   1 
ATOM   747  N N     . LEU A 1 129 ? 136.288 165.723 175.745 1.00 37.83  ? 129 LEU A N     1 
ATOM   748  C CA    . LEU A 1 129 ? 134.895 165.906 175.339 1.00 35.70  ? 129 LEU A CA    1 
ATOM   749  C C     . LEU A 1 129 ? 134.477 167.370 175.383 1.00 40.50  ? 129 LEU A C     1 
ATOM   750  O O     . LEU A 1 129 ? 133.745 167.836 174.503 1.00 44.29  ? 129 LEU A O     1 
ATOM   751  C CB    . LEU A 1 129 ? 133.968 165.064 176.214 1.00 33.91  ? 129 LEU A CB    1 
ATOM   752  C CG    . LEU A 1 129 ? 132.486 165.122 175.830 1.00 34.11  ? 129 LEU A CG    1 
ATOM   753  C CD1   . LEU A 1 129 ? 132.292 164.851 174.347 1.00 33.38  ? 129 LEU A CD1   1 
ATOM   754  C CD2   . LEU A 1 129 ? 131.669 164.139 176.657 1.00 37.45  ? 129 LEU A CD2   1 
ATOM   755  N N     . GLU A 1 130 ? 134.914 168.109 176.405 1.00 41.26  ? 130 GLU A N     1 
ATOM   756  C CA    . GLU A 1 130 ? 134.553 169.521 176.490 1.00 42.06  ? 130 GLU A CA    1 
ATOM   757  C C     . GLU A 1 130 ? 135.114 170.305 175.309 1.00 43.16  ? 130 GLU A C     1 
ATOM   758  O O     . GLU A 1 130 ? 134.424 171.156 174.733 1.00 44.40  ? 130 GLU A O     1 
ATOM   759  C CB    . GLU A 1 130 ? 135.035 170.108 177.816 1.00 44.06  ? 130 GLU A CB    1 
ATOM   760  C CG    . GLU A 1 130 ? 134.295 169.561 179.028 1.00 58.23  ? 130 GLU A CG    1 
ATOM   761  C CD    . GLU A 1 130 ? 132.800 169.825 178.968 1.00 64.02  ? 130 GLU A CD    1 
ATOM   762  O OE1   . GLU A 1 130 ? 132.401 170.886 178.442 1.00 56.80  ? 130 GLU A OE1   1 
ATOM   763  O OE2   . GLU A 1 130 ? 132.023 168.971 179.444 1.00 68.54  ? 130 GLU A OE2   1 
ATOM   764  N N     . GLU A 1 131 ? 136.361 170.022 174.928 1.00 39.07  ? 131 GLU A N     1 
ATOM   765  C CA    . GLU A 1 131 ? 136.931 170.638 173.735 1.00 35.03  ? 131 GLU A CA    1 
ATOM   766  C C     . GLU A 1 131 ? 136.163 170.231 172.485 1.00 32.49  ? 131 GLU A C     1 
ATOM   767  O O     . GLU A 1 131 ? 135.935 171.055 171.591 1.00 38.04  ? 131 GLU A O     1 
ATOM   768  C CB    . GLU A 1 131 ? 138.406 170.261 173.606 1.00 37.85  ? 131 GLU A CB    1 
ATOM   769  C CG    . GLU A 1 131 ? 139.147 170.954 172.469 1.00 42.95  ? 131 GLU A CG    1 
ATOM   770  C CD    . GLU A 1 131 ? 139.633 172.342 172.837 1.00 47.75  ? 131 GLU A CD    1 
ATOM   771  O OE1   . GLU A 1 131 ? 139.191 172.880 173.874 1.00 47.53  ? 131 GLU A OE1   1 
ATOM   772  O OE2   . GLU A 1 131 ? 140.464 172.895 172.089 1.00 53.01  ? 131 GLU A OE2   1 
ATOM   773  N N     . GLN A 1 132 ? 135.762 168.960 172.400 1.00 29.47  ? 132 GLN A N     1 
ATOM   774  C CA    . GLN A 1 132 ? 134.991 168.505 171.248 1.00 31.19  ? 132 GLN A CA    1 
ATOM   775  C C     . GLN A 1 132 ? 133.683 169.269 171.128 1.00 31.75  ? 132 GLN A C     1 
ATOM   776  O O     . GLN A 1 132 ? 133.323 169.725 170.039 1.00 40.06  ? 132 GLN A O     1 
ATOM   777  C CB    . GLN A 1 132 ? 134.719 167.007 171.351 1.00 32.24  ? 132 GLN A CB    1 
ATOM   778  C CG    . GLN A 1 132 ? 135.939 166.130 171.196 1.00 30.77  ? 132 GLN A CG    1 
ATOM   779  C CD    . GLN A 1 132 ? 135.586 164.665 171.200 1.00 36.51  ? 132 GLN A CD    1 
ATOM   780  O OE1   . GLN A 1 132 ? 134.417 164.297 171.097 1.00 43.94  ? 132 GLN A OE1   1 
ATOM   781  N NE2   . GLN A 1 132 ? 136.593 163.812 171.324 1.00 40.78  ? 132 GLN A NE2   1 
ATOM   782  N N     . LEU A 1 133 ? 132.969 169.438 172.241 1.00 28.50  ? 133 LEU A N     1 
ATOM   783  C CA    . LEU A 1 133 ? 131.710 170.175 172.212 1.00 31.45  ? 133 LEU A CA    1 
ATOM   784  C C     . LEU A 1 133 ? 131.934 171.643 171.874 1.00 35.26  ? 133 LEU A C     1 
ATOM   785  O O     . LEU A 1 133 ? 131.175 172.228 171.088 1.00 43.32  ? 133 LEU A O     1 
ATOM   786  C CB    . LEU A 1 133 ? 130.988 170.034 173.551 1.00 33.92  ? 133 LEU A CB    1 
ATOM   787  C CG    . LEU A 1 133 ? 130.403 168.663 173.888 1.00 33.01  ? 133 LEU A CG    1 
ATOM   788  C CD1   . LEU A 1 133 ? 129.804 168.673 175.281 1.00 32.84  ? 133 LEU A CD1   1 
ATOM   789  C CD2   . LEU A 1 133 ? 129.360 168.259 172.867 1.00 31.55  ? 133 LEU A CD2   1 
ATOM   790  N N     . ARG A 1 134 ? 132.969 172.256 172.454 1.00 30.88  ? 134 ARG A N     1 
ATOM   791  C CA    . ARG A 1 134 ? 133.234 173.665 172.192 1.00 32.58  ? 134 ARG A CA    1 
ATOM   792  C C     . ARG A 1 134 ? 133.557 173.904 170.723 1.00 33.58  ? 134 ARG A C     1 
ATOM   793  O O     . ARG A 1 134 ? 133.080 174.875 170.125 1.00 40.89  ? 134 ARG A O     1 
ATOM   794  C CB    . ARG A 1 134 ? 134.376 174.159 173.079 1.00 33.67  ? 134 ARG A CB    1 
ATOM   795  C CG    . ARG A 1 134 ? 134.591 175.659 173.028 1.00 36.08  ? 134 ARG A CG    1 
ATOM   796  C CD    . ARG A 1 134 ? 135.803 176.068 173.842 1.00 37.26  ? 134 ARG A CD    1 
ATOM   797  N NE    . ARG A 1 134 ? 137.032 175.496 173.308 1.00 38.79  ? 134 ARG A NE    1 
ATOM   798  C CZ    . ARG A 1 134 ? 137.782 176.068 172.377 1.00 42.22  ? 134 ARG A CZ    1 
ATOM   799  N NH1   . ARG A 1 134 ? 137.457 177.236 171.848 1.00 49.03  ? 134 ARG A NH1   1 
ATOM   800  N NH2   . ARG A 1 134 ? 138.885 175.452 171.964 1.00 37.63  ? 134 ARG A NH2   1 
ATOM   801  N N     . VAL A 1 135 ? 134.368 173.031 170.123 1.00 28.97  ? 135 VAL A N     1 
ATOM   802  C CA    . VAL A 1 135 ? 134.687 173.180 168.708 1.00 27.51  ? 135 VAL A CA    1 
ATOM   803  C C     . VAL A 1 135 ? 133.463 172.882 167.848 1.00 29.38  ? 135 VAL A C     1 
ATOM   804  O O     . VAL A 1 135 ? 133.185 173.594 166.875 1.00 36.55  ? 135 VAL A O     1 
ATOM   805  C CB    . VAL A 1 135 ? 135.882 172.286 168.333 1.00 25.85  ? 135 VAL A CB    1 
ATOM   806  C CG1   . VAL A 1 135 ? 136.168 172.374 166.845 1.00 29.97  ? 135 VAL A CG1   1 
ATOM   807  C CG2   . VAL A 1 135 ? 137.107 172.687 169.127 1.00 26.99  ? 135 VAL A CG2   1 
ATOM   808  N N     . GLY A 1 136 ? 132.707 171.841 168.199 1.00 23.75  ? 136 GLY A N     1 
ATOM   809  C CA    . GLY A 1 136 ? 131.592 171.429 167.367 1.00 24.89  ? 136 GLY A CA    1 
ATOM   810  C C     . GLY A 1 136 ? 130.463 172.438 167.331 1.00 30.96  ? 136 GLY A C     1 
ATOM   811  O O     . GLY A 1 136 ? 129.829 172.627 166.290 1.00 41.05  ? 136 GLY A O     1 
ATOM   812  N N     . THR A 1 137 ? 130.180 173.088 168.461 1.00 27.10  ? 137 THR A N     1 
ATOM   813  C CA    . THR A 1 137 ? 129.134 174.106 168.468 1.00 33.89  ? 137 THR A CA    1 
ATOM   814  C C     . THR A 1 137 ? 129.491 175.257 167.534 1.00 40.19  ? 137 THR A C     1 
ATOM   815  O O     . THR A 1 137 ? 128.658 175.712 166.738 1.00 45.00  ? 137 THR A O     1 
ATOM   816  C CB    . THR A 1 137 ? 128.903 174.619 169.888 1.00 40.68  ? 137 THR A CB    1 
ATOM   817  O OG1   . THR A 1 137 ? 128.546 173.525 170.740 1.00 43.60  ? 137 THR A OG1   1 
ATOM   818  C CG2   . THR A 1 137 ? 127.784 175.650 169.905 1.00 44.97  ? 137 THR A CG2   1 
ATOM   819  N N     . LEU A 1 138 ? 130.741 175.722 167.600 1.00 36.27  ? 138 LEU A N     1 
ATOM   820  C CA    . LEU A 1 138 ? 131.189 176.784 166.707 1.00 36.36  ? 138 LEU A CA    1 
ATOM   821  C C     . LEU A 1 138 ? 131.125 176.343 165.252 1.00 40.17  ? 138 LEU A C     1 
ATOM   822  O O     . LEU A 1 138 ? 130.702 177.111 164.380 1.00 46.49  ? 138 LEU A O     1 
ATOM   823  C CB    . LEU A 1 138 ? 132.611 177.208 167.067 1.00 32.45  ? 138 LEU A CB    1 
ATOM   824  C CG    . LEU A 1 138 ? 132.852 177.785 168.459 1.00 37.67  ? 138 LEU A CG    1 
ATOM   825  C CD1   . LEU A 1 138 ? 134.331 178.047 168.663 1.00 34.85  ? 138 LEU A CD1   1 
ATOM   826  C CD2   . LEU A 1 138 ? 132.044 179.056 168.660 1.00 47.23  ? 138 LEU A CD2   1 
ATOM   827  N N     . CYS A 1 139 ? 131.546 175.108 164.969 1.00 34.76  ? 139 CYS A N     1 
ATOM   828  C CA    . CYS A 1 139 ? 131.528 174.622 163.594 1.00 31.46  ? 139 CYS A CA    1 
ATOM   829  C C     . CYS A 1 139 ? 130.108 174.530 163.054 1.00 33.81  ? 139 CYS A C     1 
ATOM   830  O O     . CYS A 1 139 ? 129.851 174.889 161.899 1.00 38.83  ? 139 CYS A O     1 
ATOM   831  C CB    . CYS A 1 139 ? 132.225 173.269 163.510 1.00 28.86  ? 139 CYS A CB    1 
ATOM   832  S SG    . CYS A 1 139 ? 133.958 173.339 163.950 1.00 27.19  ? 139 CYS A SG    1 
ATOM   833  N N     . HIS A 1 140 ? 129.173 174.042 163.868 1.00 34.56  ? 140 HIS A N     1 
ATOM   834  C CA    . HIS A 1 140 ? 127.785 173.964 163.431 1.00 39.92  ? 140 HIS A CA    1 
ATOM   835  C C     . HIS A 1 140 ? 127.200 175.352 163.214 1.00 43.52  ? 140 HIS A C     1 
ATOM   836  O O     . HIS A 1 140 ? 126.433 175.570 162.268 1.00 44.81  ? 140 HIS A O     1 
ATOM   837  C CB    . HIS A 1 140 ? 126.953 173.186 164.448 1.00 34.89  ? 140 HIS A CB    1 
ATOM   838  C CG    . HIS A 1 140 ? 125.565 172.879 163.982 1.00 35.08  ? 140 HIS A CG    1 
ATOM   839  N ND1   . HIS A 1 140 ? 124.502 173.728 164.200 1.00 40.84  ? 140 HIS A ND1   1 
ATOM   840  C CD2   . HIS A 1 140 ? 125.066 171.817 163.307 1.00 35.38  ? 140 HIS A CD2   1 
ATOM   841  C CE1   . HIS A 1 140 ? 123.408 173.201 163.681 1.00 43.84  ? 140 HIS A CE1   1 
ATOM   842  N NE2   . HIS A 1 140 ? 123.722 172.042 163.133 1.00 38.17  ? 140 HIS A NE2   1 
ATOM   843  N N     . GLU A 1 141 ? 127.548 176.307 164.081 1.00 41.93  ? 141 GLU A N     1 
ATOM   844  C CA    . GLU A 1 141 ? 127.033 177.661 163.917 1.00 45.38  ? 141 GLU A CA    1 
ATOM   845  C C     . GLU A 1 141 ? 127.613 178.349 162.687 1.00 44.50  ? 141 GLU A C     1 
ATOM   846  O O     . GLU A 1 141 ? 126.922 179.150 162.048 1.00 46.79  ? 141 GLU A O     1 
ATOM   847  C CB    . GLU A 1 141 ? 127.320 178.489 165.169 1.00 47.07  ? 141 GLU A CB    1 
ATOM   848  C CG    . GLU A 1 141 ? 126.483 178.101 166.374 1.00 54.30  ? 141 GLU A CG    1 
ATOM   849  C CD    . GLU A 1 141 ? 126.768 178.968 167.584 1.00 69.87  ? 141 GLU A CD    1 
ATOM   850  O OE1   . GLU A 1 141 ? 127.775 179.708 167.563 1.00 65.96  ? 141 GLU A OE1   1 
ATOM   851  O OE2   . GLU A 1 141 ? 125.984 178.914 168.554 1.00 77.44  ? 141 GLU A OE2   1 
ATOM   852  N N     . HIS A 1 142 ? 128.866 178.057 162.339 1.00 40.24  ? 142 HIS A N     1 
ATOM   853  C CA    . HIS A 1 142 ? 129.574 178.802 161.305 1.00 40.01  ? 142 HIS A CA    1 
ATOM   854  C C     . HIS A 1 142 ? 129.840 177.979 160.048 1.00 34.67  ? 142 HIS A C     1 
ATOM   855  O O     . HIS A 1 142 ? 130.699 178.350 159.242 1.00 37.30  ? 142 HIS A O     1 
ATOM   856  C CB    . HIS A 1 142 ? 130.882 179.355 161.868 1.00 43.44  ? 142 HIS A CB    1 
ATOM   857  C CG    . HIS A 1 142 ? 130.700 180.174 163.106 1.00 50.24  ? 142 HIS A CG    1 
ATOM   858  N ND1   . HIS A 1 142 ? 129.489 180.732 163.455 1.00 56.30  ? 142 HIS A ND1   1 
ATOM   859  C CD2   . HIS A 1 142 ? 131.569 180.521 164.083 1.00 54.47  ? 142 HIS A CD2   1 
ATOM   860  C CE1   . HIS A 1 142 ? 129.622 181.392 164.591 1.00 62.22  ? 142 HIS A CE1   1 
ATOM   861  N NE2   . HIS A 1 142 ? 130.875 181.279 164.993 1.00 59.82  ? 142 HIS A NE2   1 
ATOM   862  N N     . GLY A 1 143 ? 129.132 176.869 159.865 1.00 34.60  ? 143 GLY A N     1 
ATOM   863  C CA    . GLY A 1 143 ? 129.191 176.158 158.604 1.00 35.89  ? 143 GLY A CA    1 
ATOM   864  C C     . GLY A 1 143 ? 130.464 175.393 158.329 1.00 33.20  ? 143 GLY A C     1 
ATOM   865  O O     . GLY A 1 143 ? 130.689 174.992 157.184 1.00 35.45  ? 143 GLY A O     1 
ATOM   866  N N     . VAL A 1 144 ? 131.305 175.176 159.329 1.00 29.18  ? 144 VAL A N     1 
ATOM   867  C CA    . VAL A 1 144 ? 132.523 174.397 159.156 1.00 29.84  ? 144 VAL A CA    1 
ATOM   868  C C     . VAL A 1 144 ? 132.199 172.926 159.378 1.00 34.77  ? 144 VAL A C     1 
ATOM   869  O O     . VAL A 1 144 ? 131.567 172.564 160.377 1.00 36.98  ? 144 VAL A O     1 
ATOM   870  C CB    . VAL A 1 144 ? 133.622 174.872 160.120 1.00 35.13  ? 144 VAL A CB    1 
ATOM   871  C CG1   . VAL A 1 144 ? 134.937 174.179 159.805 1.00 35.19  ? 144 VAL A CG1   1 
ATOM   872  C CG2   . VAL A 1 144 ? 133.780 176.381 160.046 1.00 36.44  ? 144 VAL A CG2   1 
ATOM   873  N N     . CYS A 1 145 ? 132.621 172.080 158.442 1.00 35.24  ? 145 CYS A N     1 
ATOM   874  C CA    . CYS A 1 145 ? 132.470 170.641 158.610 1.00 31.10  ? 145 CYS A CA    1 
ATOM   875  C C     . CYS A 1 145 ? 133.316 170.161 159.782 1.00 29.84  ? 145 CYS A C     1 
ATOM   876  O O     . CYS A 1 145 ? 134.471 170.562 159.937 1.00 34.18  ? 145 CYS A O     1 
ATOM   877  C CB    . CYS A 1 145 ? 132.874 169.909 157.331 1.00 35.31  ? 145 CYS A CB    1 
ATOM   878  S SG    . CYS A 1 145 ? 131.907 170.359 155.870 1.00 60.93  ? 145 CYS A SG    1 
ATOM   879  N N     . PHE A 1 146 ? 132.734 169.294 160.609 1.00 27.60  ? 146 PHE A N     1 
ATOM   880  C CA    . PHE A 1 146 ? 133.317 168.899 161.884 1.00 24.33  ? 146 PHE A CA    1 
ATOM   881  C C     . PHE A 1 146 ? 133.384 167.382 161.964 1.00 27.92  ? 146 PHE A C     1 
ATOM   882  O O     . PHE A 1 146 ? 132.382 166.700 161.732 1.00 31.92  ? 146 PHE A O     1 
ATOM   883  C CB    . PHE A 1 146 ? 132.481 169.473 163.031 1.00 22.46  ? 146 PHE A CB    1 
ATOM   884  C CG    . PHE A 1 146 ? 132.973 169.113 164.396 1.00 20.90  ? 146 PHE A CG    1 
ATOM   885  C CD1   . PHE A 1 146 ? 134.163 169.617 164.876 1.00 25.46  ? 146 PHE A CD1   1 
ATOM   886  C CD2   . PHE A 1 146 ? 132.219 168.298 165.218 1.00 21.95  ? 146 PHE A CD2   1 
ATOM   887  C CE1   . PHE A 1 146 ? 134.603 169.296 166.138 1.00 27.30  ? 146 PHE A CE1   1 
ATOM   888  C CE2   . PHE A 1 146 ? 132.653 167.979 166.480 1.00 24.18  ? 146 PHE A CE2   1 
ATOM   889  C CZ    . PHE A 1 146 ? 133.846 168.480 166.941 1.00 24.50  ? 146 PHE A CZ    1 
ATOM   890  N N     . LEU A 1 147 ? 134.562 166.851 162.277 1.00 24.70  ? 147 LEU A N     1 
ATOM   891  C CA    . LEU A 1 147 ? 134.750 165.413 162.414 1.00 21.64  ? 147 LEU A CA    1 
ATOM   892  C C     . LEU A 1 147 ? 135.440 165.121 163.735 1.00 25.56  ? 147 LEU A C     1 
ATOM   893  O O     . LEU A 1 147 ? 136.376 165.828 164.111 1.00 27.31  ? 147 LEU A O     1 
ATOM   894  C CB    . LEU A 1 147 ? 135.567 164.851 161.249 1.00 20.58  ? 147 LEU A CB    1 
ATOM   895  C CG    . LEU A 1 147 ? 134.755 164.183 160.142 1.00 26.60  ? 147 LEU A CG    1 
ATOM   896  C CD1   . LEU A 1 147 ? 135.251 164.595 158.769 1.00 30.91  ? 147 LEU A CD1   1 
ATOM   897  C CD2   . LEU A 1 147 ? 134.825 162.679 160.300 1.00 30.99  ? 147 LEU A CD2   1 
ATOM   898  N N     . VAL A 1 148 ? 134.958 164.109 164.450 1.00 27.22  ? 148 VAL A N     1 
ATOM   899  C CA    . VAL A 1 148 ? 135.616 163.593 165.646 1.00 23.25  ? 148 VAL A CA    1 
ATOM   900  C C     . VAL A 1 148 ? 136.006 162.147 165.384 1.00 25.12  ? 148 VAL A C     1 
ATOM   901  O O     . VAL A 1 148 ? 135.160 161.333 164.999 1.00 30.79  ? 148 VAL A O     1 
ATOM   902  C CB    . VAL A 1 148 ? 134.712 163.694 166.885 1.00 22.51  ? 148 VAL A CB    1 
ATOM   903  C CG1   . VAL A 1 148 ? 135.306 162.907 168.037 1.00 25.20  ? 148 VAL A CG1   1 
ATOM   904  C CG2   . VAL A 1 148 ? 134.522 165.134 167.281 1.00 26.38  ? 148 VAL A CG2   1 
ATOM   905  N N     . ALA A 1 149 ? 137.275 161.823 165.587 1.00 21.23  ? 149 ALA A N     1 
ATOM   906  C CA    . ALA A 1 149 ? 137.729 160.446 165.479 1.00 21.24  ? 149 ALA A CA    1 
ATOM   907  C C     . ALA A 1 149 ? 138.567 160.114 166.699 1.00 30.71  ? 149 ALA A C     1 
ATOM   908  O O     . ALA A 1 149 ? 139.502 160.850 167.029 1.00 36.56  ? 149 ALA A O     1 
ATOM   909  C CB    . ALA A 1 149 ? 138.532 160.225 164.196 1.00 25.37  ? 149 ALA A CB    1 
ATOM   910  N N     . ASP A 1 150 ? 138.237 159.014 167.371 1.00 34.39  ? 150 ASP A N     1 
ATOM   911  C CA    . ASP A 1 150 ? 139.044 158.567 168.498 1.00 37.56  ? 150 ASP A CA    1 
ATOM   912  C C     . ASP A 1 150 ? 139.030 157.050 168.571 1.00 33.57  ? 150 ASP A C     1 
ATOM   913  O O     . ASP A 1 150 ? 138.012 156.409 168.308 1.00 39.39  ? 150 ASP A O     1 
ATOM   914  C CB    . ASP A 1 150 ? 138.549 159.159 169.821 1.00 42.27  ? 150 ASP A CB    1 
ATOM   915  C CG    . ASP A 1 150 ? 139.567 159.021 170.932 1.00 48.80  ? 150 ASP A CG    1 
ATOM   916  O OD1   . ASP A 1 150 ? 140.752 158.773 170.625 1.00 50.40  ? 150 ASP A OD1   1 
ATOM   917  O OD2   . ASP A 1 150 ? 139.182 159.153 172.112 1.00 56.33  ? 150 ASP A OD2   1 
ATOM   918  N N     . THR A 1 151 ? 140.166 156.474 168.951 1.00 31.13  ? 151 THR A N     1 
ATOM   919  C CA    . THR A 1 151 ? 140.250 155.039 169.170 1.00 32.60  ? 151 THR A CA    1 
ATOM   920  C C     . THR A 1 151 ? 140.753 154.788 170.582 1.00 34.53  ? 151 THR A C     1 
ATOM   921  O O     . THR A 1 151 ? 141.735 155.396 171.019 1.00 42.03  ? 151 THR A O     1 
ATOM   922  C CB    . THR A 1 151 ? 141.152 154.346 168.134 1.00 33.75  ? 151 THR A CB    1 
ATOM   923  O OG1   . THR A 1 151 ? 141.296 152.961 168.476 1.00 40.25  ? 151 THR A OG1   1 
ATOM   924  C CG2   . THR A 1 151 ? 142.521 154.990 168.068 1.00 33.40  ? 151 THR A CG2   1 
ATOM   925  N N     . ARG A 1 152 ? 140.052 153.915 171.296 1.00 31.65  ? 152 ARG A N     1 
ATOM   926  C CA    . ARG A 1 152 ? 140.368 153.515 172.661 1.00 32.01  ? 152 ARG A CA    1 
ATOM   927  C C     . ARG A 1 152 ? 140.582 152.005 172.613 1.00 33.82  ? 152 ARG A C     1 
ATOM   928  O O     . ARG A 1 152 ? 139.624 151.223 172.606 1.00 39.75  ? 152 ARG A O     1 
ATOM   929  C CB    . ARG A 1 152 ? 139.260 153.914 173.629 1.00 32.53  ? 152 ARG A CB    1 
ATOM   930  C CG    . ARG A 1 152 ? 138.950 155.405 173.650 1.00 37.53  ? 152 ARG A CG    1 
ATOM   931  C CD    . ARG A 1 152 ? 140.053 156.203 174.318 1.00 41.03  ? 152 ARG A CD    1 
ATOM   932  N NE    . ARG A 1 152 ? 139.687 156.665 175.652 1.00 42.64  ? 152 ARG A NE    1 
ATOM   933  C CZ    . ARG A 1 152 ? 139.010 157.777 175.900 1.00 45.48  ? 152 ARG A CZ    1 
ATOM   934  N NH1   . ARG A 1 152 ? 138.548 158.539 174.922 1.00 45.06  ? 152 ARG A NH1   1 
ATOM   935  N NH2   . ARG A 1 152 ? 138.794 158.139 177.162 1.00 45.45  ? 152 ARG A NH2   1 
ATOM   936  N N     . GLY A 1 153 ? 141.848 151.605 172.526 1.00 31.71  ? 153 GLY A N     1 
ATOM   937  C CA    . GLY A 1 153 ? 142.196 150.206 172.453 1.00 29.99  ? 153 GLY A CA    1 
ATOM   938  C C     . GLY A 1 153 ? 141.655 149.538 171.210 1.00 32.37  ? 153 GLY A C     1 
ATOM   939  O O     . GLY A 1 153 ? 142.160 149.757 170.105 1.00 32.61  ? 153 GLY A O     1 
ATOM   940  N N     . LEU A 1 154 ? 140.629 148.708 171.382 1.00 32.30  ? 154 LEU A N     1 
ATOM   941  C CA    . LEU A 1 154 ? 139.992 148.015 170.274 1.00 30.49  ? 154 LEU A CA    1 
ATOM   942  C C     . LEU A 1 154 ? 138.601 148.556 169.958 1.00 34.71  ? 154 LEU A C     1 
ATOM   943  O O     . LEU A 1 154 ? 137.799 147.847 169.344 1.00 38.80  ? 154 LEU A O     1 
ATOM   944  C CB    . LEU A 1 154 ? 139.924 146.516 170.565 1.00 33.19  ? 154 LEU A CB    1 
ATOM   945  C CG    . LEU A 1 154 ? 141.259 145.775 170.492 1.00 35.79  ? 154 LEU A CG    1 
ATOM   946  C CD1   . LEU A 1 154 ? 141.182 144.464 171.257 1.00 32.39  ? 154 LEU A CD1   1 
ATOM   947  C CD2   . LEU A 1 154 ? 141.640 145.529 169.044 1.00 37.43  ? 154 LEU A CD2   1 
ATOM   948  N N     . VAL A 1 155 ? 138.293 149.790 170.356 1.00 31.33  ? 155 VAL A N     1 
ATOM   949  C CA    . VAL A 1 155 ? 137.014 150.405 170.021 1.00 26.99  ? 155 VAL A CA    1 
ATOM   950  C C     . VAL A 1 155 ? 137.272 151.732 169.317 1.00 30.90  ? 155 VAL A C     1 
ATOM   951  O O     . VAL A 1 155 ? 138.163 152.488 169.712 1.00 31.72  ? 155 VAL A O     1 
ATOM   952  C CB    . VAL A 1 155 ? 136.134 150.606 171.271 1.00 23.62  ? 155 VAL A CB    1 
ATOM   953  C CG1   . VAL A 1 155 ? 134.762 151.103 170.871 1.00 26.48  ? 155 VAL A CG1   1 
ATOM   954  C CG2   . VAL A 1 155 ? 136.023 149.309 172.059 1.00 31.85  ? 155 VAL A CG2   1 
ATOM   955  N N     . GLY A 1 156 ? 136.511 152.008 168.266 1.00 32.61  ? 156 GLY A N     1 
ATOM   956  C CA    . GLY A 1 156 ? 136.662 153.239 167.498 1.00 27.10  ? 156 GLY A CA    1 
ATOM   957  C C     . GLY A 1 156 ? 135.364 154.018 167.411 1.00 26.56  ? 156 GLY A C     1 
ATOM   958  O O     . GLY A 1 156 ? 134.311 153.446 167.133 1.00 33.30  ? 156 GLY A O     1 
ATOM   959  N N     . GLN A 1 157 ? 135.451 155.326 167.644 1.00 21.97  ? 157 GLN A N     1 
ATOM   960  C CA    . GLN A 1 157 ? 134.322 156.244 167.565 1.00 21.16  ? 157 GLN A CA    1 
ATOM   961  C C     . GLN A 1 157 ? 134.582 157.284 166.483 1.00 28.43  ? 157 GLN A C     1 
ATOM   962  O O     . GLN A 1 157 ? 135.643 157.922 166.475 1.00 30.69  ? 157 GLN A O     1 
ATOM   963  C CB    . GLN A 1 157 ? 134.099 156.944 168.906 1.00 19.69  ? 157 GLN A CB    1 
ATOM   964  C CG    . GLN A 1 157 ? 133.061 158.047 168.875 1.00 17.15  ? 157 GLN A CG    1 
ATOM   965  C CD    . GLN A 1 157 ? 133.184 158.990 170.050 1.00 23.98  ? 157 GLN A CD    1 
ATOM   966  O OE1   . GLN A 1 157 ? 134.222 159.617 170.250 1.00 35.76  ? 157 GLN A OE1   1 
ATOM   967  N NE2   . GLN A 1 157 ? 132.128 159.090 170.843 1.00 24.85  ? 157 GLN A NE2   1 
ATOM   968  N N     . LEU A 1 158 ? 133.613 157.462 165.583 1.00 25.84  ? 158 LEU A N     1 
ATOM   969  C CA    . LEU A 1 158 ? 133.677 158.494 164.556 1.00 23.16  ? 158 LEU A CA    1 
ATOM   970  C C     . LEU A 1 158 ? 132.360 159.255 164.534 1.00 24.84  ? 158 LEU A C     1 
ATOM   971  O O     . LEU A 1 158 ? 131.289 158.644 164.526 1.00 31.80  ? 158 LEU A O     1 
ATOM   972  C CB    . LEU A 1 158 ? 133.971 157.885 163.181 1.00 18.70  ? 158 LEU A CB    1 
ATOM   973  C CG    . LEU A 1 158 ? 134.530 158.812 162.105 1.00 26.21  ? 158 LEU A CG    1 
ATOM   974  C CD1   . LEU A 1 158 ? 135.344 158.010 161.112 1.00 28.13  ? 158 LEU A CD1   1 
ATOM   975  C CD2   . LEU A 1 158 ? 133.424 159.563 161.391 1.00 28.03  ? 158 LEU A CD2   1 
ATOM   976  N N     . PHE A 1 159 ? 132.444 160.583 164.530 1.00 17.08  ? 159 PHE A N     1 
ATOM   977  C CA    . PHE A 1 159 ? 131.285 161.462 164.473 1.00 18.43  ? 159 PHE A CA    1 
ATOM   978  C C     . PHE A 1 159 ? 131.465 162.468 163.347 1.00 25.75  ? 159 PHE A C     1 
ATOM   979  O O     . PHE A 1 159 ? 132.529 163.084 163.227 1.00 29.62  ? 159 PHE A O     1 
ATOM   980  C CB    . PHE A 1 159 ? 131.079 162.195 165.798 1.00 19.34  ? 159 PHE A CB    1 
ATOM   981  C CG    . PHE A 1 159 ? 130.045 163.281 165.738 1.00 15.74  ? 159 PHE A CG    1 
ATOM   982  C CD1   . PHE A 1 159 ? 128.708 162.976 165.583 1.00 17.28  ? 159 PHE A CD1   1 
ATOM   983  C CD2   . PHE A 1 159 ? 130.412 164.608 165.847 1.00 19.29  ? 159 PHE A CD2   1 
ATOM   984  C CE1   . PHE A 1 159 ? 127.761 163.967 165.532 1.00 18.11  ? 159 PHE A CE1   1 
ATOM   985  C CE2   . PHE A 1 159 ? 129.466 165.605 165.799 1.00 21.00  ? 159 PHE A CE2   1 
ATOM   986  C CZ    . PHE A 1 159 ? 128.139 165.283 165.642 1.00 20.16  ? 159 PHE A CZ    1 
ATOM   987  N N     . CYS A 1 160 ? 130.424 162.638 162.537 1.00 27.55  ? 160 CYS A N     1 
ATOM   988  C CA    . CYS A 1 160 ? 130.403 163.620 161.463 1.00 21.49  ? 160 CYS A CA    1 
ATOM   989  C C     . CYS A 1 160 ? 129.355 164.685 161.753 1.00 23.58  ? 160 CYS A C     1 
ATOM   990  O O     . CYS A 1 160 ? 128.303 164.397 162.333 1.00 29.90  ? 160 CYS A O     1 
ATOM   991  C CB    . CYS A 1 160 ? 130.110 162.960 160.115 1.00 27.28  ? 160 CYS A CB    1 
ATOM   992  S SG    . CYS A 1 160 ? 131.446 161.943 159.455 1.00 42.04  ? 160 CYS A SG    1 
ATOM   993  N N     . ASP A 1 161 ? 129.653 165.919 161.351 1.00 21.46  ? 161 ASP A N     1 
ATOM   994  C CA    . ASP A 1 161 ? 128.709 167.030 161.448 1.00 21.27  ? 161 ASP A CA    1 
ATOM   995  C C     . ASP A 1 161 ? 128.996 167.941 160.258 1.00 32.36  ? 161 ASP A C     1 
ATOM   996  O O     . ASP A 1 161 ? 129.900 168.779 160.318 1.00 37.29  ? 161 ASP A O     1 
ATOM   997  C CB    . ASP A 1 161 ? 128.853 167.767 162.771 1.00 23.19  ? 161 ASP A CB    1 
ATOM   998  C CG    . ASP A 1 161 ? 128.032 169.043 162.826 1.00 32.53  ? 161 ASP A CG    1 
ATOM   999  O OD1   . ASP A 1 161 ? 127.103 169.207 162.010 1.00 29.96  ? 161 ASP A OD1   1 
ATOM   1000 O OD2   . ASP A 1 161 ? 128.320 169.891 163.695 1.00 41.66  ? 161 ASP A OD2   1 
ATOM   1001 N N     . PHE A 1 162 ? 128.229 167.768 159.184 1.00 30.00  ? 162 PHE A N     1 
ATOM   1002 C CA    . PHE A 1 162 ? 128.458 168.494 157.944 1.00 20.10  ? 162 PHE A CA    1 
ATOM   1003 C C     . PHE A 1 162 ? 127.477 169.643 157.751 1.00 19.93  ? 162 PHE A C     1 
ATOM   1004 O O     . PHE A 1 162 ? 127.351 170.162 156.637 1.00 30.69  ? 162 PHE A O     1 
ATOM   1005 C CB    . PHE A 1 162 ? 128.405 167.537 156.753 1.00 21.64  ? 162 PHE A CB    1 
ATOM   1006 C CG    . PHE A 1 162 ? 129.613 166.650 156.629 1.00 24.49  ? 162 PHE A CG    1 
ATOM   1007 C CD1   . PHE A 1 162 ? 130.562 166.597 157.631 1.00 25.12  ? 162 PHE A CD1   1 
ATOM   1008 C CD2   . PHE A 1 162 ? 129.806 165.885 155.496 1.00 30.46  ? 162 PHE A CD2   1 
ATOM   1009 C CE1   . PHE A 1 162 ? 131.672 165.787 157.512 1.00 32.93  ? 162 PHE A CE1   1 
ATOM   1010 C CE2   . PHE A 1 162 ? 130.916 165.075 155.371 1.00 30.24  ? 162 PHE A CE2   1 
ATOM   1011 C CZ    . PHE A 1 162 ? 131.848 165.025 156.380 1.00 32.40  ? 162 PHE A CZ    1 
ATOM   1012 N N     . GLY A 1 163 ? 126.780 170.046 158.805 1.00 16.96  ? 163 GLY A N     1 
ATOM   1013 C CA    . GLY A 1 163 ? 125.929 171.215 158.773 1.00 24.98  ? 163 GLY A CA    1 
ATOM   1014 C C     . GLY A 1 163 ? 124.458 170.869 158.629 1.00 31.82  ? 163 GLY A C     1 
ATOM   1015 O O     . GLY A 1 163 ? 124.066 169.728 158.374 1.00 31.52  ? 163 GLY A O     1 
ATOM   1016 N N     . GLU A 1 164 ? 123.630 171.901 158.808 1.00 36.44  ? 164 GLU A N     1 
ATOM   1017 C CA    . GLU A 1 164 ? 122.189 171.743 158.650 1.00 44.94  ? 164 GLU A CA    1 
ATOM   1018 C C     . GLU A 1 164 ? 121.809 171.443 157.207 1.00 51.01  ? 164 GLU A C     1 
ATOM   1019 O O     . GLU A 1 164 ? 120.855 170.696 156.962 1.00 53.23  ? 164 GLU A O     1 
ATOM   1020 C CB    . GLU A 1 164 ? 121.465 173.001 159.130 1.00 53.22  ? 164 GLU A CB    1 
ATOM   1021 C CG    . GLU A 1 164 ? 121.507 173.226 160.635 1.00 61.13  ? 164 GLU A CG    1 
ATOM   1022 C CD    . GLU A 1 164 ? 120.450 172.430 161.378 1.00 69.85  ? 164 GLU A CD    1 
ATOM   1023 O OE1   . GLU A 1 164 ? 119.745 171.622 160.737 1.00 66.01  ? 164 GLU A OE1   1 
ATOM   1024 O OE2   . GLU A 1 164 ? 120.320 172.616 162.606 1.00 65.68  ? 164 GLU A OE2   1 
ATOM   1025 N N     . ASN A 1 165 ? 122.525 172.018 156.243 1.00 49.54  ? 165 ASN A N     1 
ATOM   1026 C CA    . ASN A 1 165 ? 122.254 171.799 154.823 1.00 43.69  ? 165 ASN A CA    1 
ATOM   1027 C C     . ASN A 1 165 ? 123.578 171.534 154.116 1.00 36.95  ? 165 ASN A C     1 
ATOM   1028 O O     . ASN A 1 165 ? 124.366 172.458 153.893 1.00 45.10  ? 165 ASN A O     1 
ATOM   1029 C CB    . ASN A 1 165 ? 121.529 172.990 154.207 1.00 47.91  ? 165 ASN A CB    1 
ATOM   1030 C CG    . ASN A 1 165 ? 120.201 173.274 154.877 1.00 61.93  ? 165 ASN A CG    1 
ATOM   1031 O OD1   . ASN A 1 165 ? 119.229 172.540 154.692 1.00 68.02  ? 165 ASN A OD1   1 
ATOM   1032 N ND2   . ASN A 1 165 ? 120.149 174.348 155.656 1.00 59.81  ? 165 ASN A ND2   1 
ATOM   1033 N N     . PHE A 1 166 ? 123.822 170.274 153.767 1.00 29.80  ? 166 PHE A N     1 
ATOM   1034 C CA    . PHE A 1 166 ? 124.991 169.882 152.991 1.00 32.31  ? 166 PHE A CA    1 
ATOM   1035 C C     . PHE A 1 166 ? 124.511 169.251 151.694 1.00 47.73  ? 166 PHE A C     1 
ATOM   1036 O O     . PHE A 1 166 ? 123.727 168.298 151.718 1.00 54.16  ? 166 PHE A O     1 
ATOM   1037 C CB    . PHE A 1 166 ? 125.868 168.908 153.776 1.00 30.34  ? 166 PHE A CB    1 
ATOM   1038 C CG    . PHE A 1 166 ? 127.201 168.638 153.140 1.00 29.95  ? 166 PHE A CG    1 
ATOM   1039 C CD1   . PHE A 1 166 ? 128.272 169.483 153.367 1.00 34.61  ? 166 PHE A CD1   1 
ATOM   1040 C CD2   . PHE A 1 166 ? 127.390 167.533 152.334 1.00 32.57  ? 166 PHE A CD2   1 
ATOM   1041 C CE1   . PHE A 1 166 ? 129.501 169.234 152.792 1.00 36.85  ? 166 PHE A CE1   1 
ATOM   1042 C CE2   . PHE A 1 166 ? 128.619 167.279 151.758 1.00 32.61  ? 166 PHE A CE2   1 
ATOM   1043 C CZ    . PHE A 1 166 ? 129.672 168.129 151.987 1.00 34.47  ? 166 PHE A CZ    1 
ATOM   1044 N N     . THR A 1 167 ? 124.975 169.778 150.567 1.00 46.91  ? 167 THR A N     1 
ATOM   1045 C CA    . THR A 1 167 ? 124.581 169.265 149.263 1.00 44.34  ? 167 THR A CA    1 
ATOM   1046 C C     . THR A 1 167 ? 125.598 168.229 148.805 1.00 55.47  ? 167 THR A C     1 
ATOM   1047 O O     . THR A 1 167 ? 126.787 168.536 148.667 1.00 56.65  ? 167 THR A O     1 
ATOM   1048 C CB    . THR A 1 167 ? 124.468 170.395 148.241 1.00 50.05  ? 167 THR A CB    1 
ATOM   1049 O OG1   . THR A 1 167 ? 125.725 171.075 148.134 1.00 54.88  ? 167 THR A OG1   1 
ATOM   1050 C CG2   . THR A 1 167 ? 123.397 171.387 148.662 1.00 56.17  ? 167 THR A CG2   1 
ATOM   1051 N N     . VAL A 1 168 ? 125.133 167.005 148.582 1.00 60.78  ? 168 VAL A N     1 
ATOM   1052 C CA    . VAL A 1 168 ? 125.957 165.936 148.032 1.00 62.15  ? 168 VAL A CA    1 
ATOM   1053 C C     . VAL A 1 168 ? 125.609 165.794 146.556 1.00 69.40  ? 168 VAL A C     1 
ATOM   1054 O O     . VAL A 1 168 ? 124.449 165.558 146.199 1.00 72.25  ? 168 VAL A O     1 
ATOM   1055 C CB    . VAL A 1 168 ? 125.754 164.619 148.796 1.00 57.79  ? 168 VAL A CB    1 
ATOM   1056 C CG1   . VAL A 1 168 ? 126.481 164.673 150.128 1.00 55.06  ? 168 VAL A CG1   1 
ATOM   1057 C CG2   . VAL A 1 168 ? 124.278 164.349 149.023 1.00 58.49  ? 168 VAL A CG2   1 
ATOM   1058 N N     . GLN A 1 169 ? 126.611 165.949 145.694 1.00 65.92  ? 169 GLN A N     1 
ATOM   1059 C CA    . GLN A 1 169 ? 126.370 166.022 144.260 1.00 71.63  ? 169 GLN A CA    1 
ATOM   1060 C C     . GLN A 1 169 ? 126.386 164.663 143.574 1.00 74.77  ? 169 GLN A C     1 
ATOM   1061 O O     . GLN A 1 169 ? 125.615 164.447 142.632 1.00 77.24  ? 169 GLN A O     1 
ATOM   1062 C CB    . GLN A 1 169 ? 127.409 166.936 143.606 1.00 77.67  ? 169 GLN A CB    1 
ATOM   1063 C CG    . GLN A 1 169 ? 127.443 168.339 144.191 1.00 83.38  ? 169 GLN A CG    1 
ATOM   1064 C CD    . GLN A 1 169 ? 128.554 169.187 143.608 1.00 90.48  ? 169 GLN A CD    1 
ATOM   1065 O OE1   . GLN A 1 169 ? 129.343 168.718 142.789 1.00 85.48  ? 169 GLN A OE1   1 
ATOM   1066 N NE2   . GLN A 1 169 ? 128.624 170.444 144.030 1.00 91.03  ? 169 GLN A NE2   1 
ATOM   1067 N N     . ASP A 1 170 ? 127.237 163.741 144.020 1.00 73.77  ? 170 ASP A N     1 
ATOM   1068 C CA    . ASP A 1 170 ? 127.430 162.448 143.361 1.00 72.36  ? 170 ASP A CA    1 
ATOM   1069 C C     . ASP A 1 170 ? 127.251 161.339 144.387 1.00 71.55  ? 170 ASP A C     1 
ATOM   1070 O O     . ASP A 1 170 ? 128.231 160.777 144.892 1.00 72.88  ? 170 ASP A O     1 
ATOM   1071 C CB    . ASP A 1 170 ? 128.806 162.369 142.700 1.00 69.08  ? 170 ASP A CB    1 
ATOM   1072 C CG    . ASP A 1 170 ? 129.027 163.471 141.682 1.00 80.28  ? 170 ASP A CG    1 
ATOM   1073 O OD1   . ASP A 1 170 ? 128.095 163.758 140.902 1.00 82.69  ? 170 ASP A OD1   1 
ATOM   1074 O OD2   . ASP A 1 170 ? 130.131 164.056 141.668 1.00 81.36  ? 170 ASP A OD2   1 
ATOM   1075 N N     . PRO A 1 171 ? 126.007 160.986 144.709 1.00 71.09  ? 171 PRO A N     1 
ATOM   1076 C CA    . PRO A 1 171 ? 125.766 159.985 145.758 1.00 66.33  ? 171 PRO A CA    1 
ATOM   1077 C C     . PRO A 1 171 ? 126.040 158.555 145.314 1.00 70.11  ? 171 PRO A C     1 
ATOM   1078 O O     . PRO A 1 171 ? 125.692 157.610 146.030 1.00 71.70  ? 171 PRO A O     1 
ATOM   1079 C CB    . PRO A 1 171 ? 124.280 160.181 146.095 1.00 66.67  ? 171 PRO A CB    1 
ATOM   1080 C CG    . PRO A 1 171 ? 123.893 161.496 145.474 1.00 65.82  ? 171 PRO A CG    1 
ATOM   1081 C CD    . PRO A 1 171 ? 124.760 161.628 144.269 1.00 68.59  ? 171 PRO A CD    1 
ATOM   1082 N N     . THR A 1 172 ? 126.654 158.377 144.148 1.00 75.34  ? 172 THR A N     1 
ATOM   1083 C CA    . THR A 1 172 ? 126.930 157.055 143.606 1.00 81.16  ? 172 THR A CA    1 
ATOM   1084 C C     . THR A 1 172 ? 128.415 156.916 143.312 1.00 79.36  ? 172 THR A C     1 
ATOM   1085 O O     . THR A 1 172 ? 129.051 157.847 142.808 1.00 77.17  ? 172 THR A O     1 
ATOM   1086 C CB    . THR A 1 172 ? 126.119 156.795 142.325 1.00 83.43  ? 172 THR A CB    1 
ATOM   1087 O OG1   . THR A 1 172 ? 124.719 156.810 142.637 1.00 82.90  ? 172 THR A OG1   1 
ATOM   1088 C CG2   . THR A 1 172 ? 126.481 155.447 141.714 1.00 82.62  ? 172 THR A CG2   1 
ATOM   1089 N N     . GLU A 1 173 ? 128.965 155.749 143.648 1.00 79.43  ? 173 GLU A N     1 
ATOM   1090 C CA    . GLU A 1 173 ? 130.369 155.475 143.366 1.00 81.82  ? 173 GLU A CA    1 
ATOM   1091 C C     . GLU A 1 173 ? 130.639 155.447 141.865 1.00 90.01  ? 173 GLU A C     1 
ATOM   1092 O O     . GLU A 1 173 ? 131.574 156.092 141.378 1.00 90.44  ? 173 GLU A O     1 
ATOM   1093 C CB    . GLU A 1 173 ? 130.770 154.151 144.017 1.00 82.62  ? 173 GLU A CB    1 
ATOM   1094 C CG    . GLU A 1 173 ? 132.074 153.560 143.506 1.00 87.18  ? 173 GLU A CG    1 
ATOM   1095 C CD    . GLU A 1 173 ? 133.284 154.050 144.272 1.00 84.20  ? 173 GLU A CD    1 
ATOM   1096 O OE1   . GLU A 1 173 ? 133.152 155.024 145.041 1.00 79.52  ? 173 GLU A OE1   1 
ATOM   1097 O OE2   . GLU A 1 173 ? 134.367 153.449 144.114 1.00 82.13  ? 173 GLU A OE2   1 
ATOM   1098 N N     . ALA A 1 174 ? 129.818 154.717 141.114 1.00 95.25  ? 174 ALA A N     1 
ATOM   1099 C CA    . ALA A 1 174 ? 130.078 154.484 139.701 1.00 101.59 ? 174 ALA A CA    1 
ATOM   1100 C C     . ALA A 1 174 ? 129.655 155.682 138.850 1.00 108.32 ? 174 ALA A C     1 
ATOM   1101 O O     . ALA A 1 174 ? 128.871 156.537 139.271 1.00 105.95 ? 174 ALA A O     1 
ATOM   1102 C CB    . ALA A 1 174 ? 129.359 153.218 139.231 1.00 101.80 ? 174 ALA A CB    1 
ATOM   1103 N N     . GLU A 1 175 ? 130.205 155.736 137.636 1.00 117.10 ? 175 GLU A N     1 
ATOM   1104 C CA    . GLU A 1 175 ? 129.807 156.740 136.662 1.00 119.58 ? 175 GLU A CA    1 
ATOM   1105 C C     . GLU A 1 175 ? 128.372 156.486 136.198 1.00 119.16 ? 175 GLU A C     1 
ATOM   1106 O O     . GLU A 1 175 ? 127.878 155.358 136.276 1.00 121.04 ? 175 GLU A O     1 
ATOM   1107 C CB    . GLU A 1 175 ? 130.749 156.724 135.458 1.00 119.63 ? 175 GLU A CB    1 
ATOM   1108 C CG    . GLU A 1 175 ? 132.214 156.994 135.781 1.00 122.22 ? 175 GLU A CG    1 
ATOM   1109 C CD    . GLU A 1 175 ? 132.496 158.450 136.115 1.00 124.81 ? 175 GLU A CD    1 
ATOM   1110 O OE1   . GLU A 1 175 ? 131.618 159.307 135.882 1.00 120.69 ? 175 GLU A OE1   1 
ATOM   1111 O OE2   . GLU A 1 175 ? 133.606 158.740 136.611 1.00 129.90 ? 175 GLU A OE2   1 
ATOM   1112 N N     . PRO A 1 176 ? 127.675 157.523 135.726 1.00 116.15 ? 176 PRO A N     1 
ATOM   1113 C CA    . PRO A 1 176 ? 126.324 157.316 135.188 1.00 120.92 ? 176 PRO A CA    1 
ATOM   1114 C C     . PRO A 1 176 ? 126.332 156.349 134.012 1.00 126.60 ? 176 PRO A C     1 
ATOM   1115 O O     . PRO A 1 176 ? 127.259 156.333 133.199 1.00 124.60 ? 176 PRO A O     1 
ATOM   1116 C CB    . PRO A 1 176 ? 125.890 158.725 134.762 1.00 117.65 ? 176 PRO A CB    1 
ATOM   1117 C CG    . PRO A 1 176 ? 127.158 159.526 134.690 1.00 114.29 ? 176 PRO A CG    1 
ATOM   1118 C CD    . PRO A 1 176 ? 128.054 158.945 135.731 1.00 110.80 ? 176 PRO A CD    1 
ATOM   1119 N N     . LEU A 1 177 ? 125.280 155.537 133.933 1.00 130.97 ? 177 LEU A N     1 
ATOM   1120 C CA    . LEU A 1 177 ? 125.181 154.451 132.958 1.00 133.03 ? 177 LEU A CA    1 
ATOM   1121 C C     . LEU A 1 177 ? 124.653 155.016 131.646 1.00 136.66 ? 177 LEU A C     1 
ATOM   1122 O O     . LEU A 1 177 ? 123.451 155.212 131.464 1.00 136.01 ? 177 LEU A O     1 
ATOM   1123 C CB    . LEU A 1 177 ? 124.284 153.339 133.491 1.00 132.28 ? 177 LEU A CB    1 
ATOM   1124 C CG    . LEU A 1 177 ? 124.581 151.899 133.064 1.00 133.83 ? 177 LEU A CG    1 
ATOM   1125 C CD1   . LEU A 1 177 ? 123.765 150.933 133.909 1.00 134.70 ? 177 LEU A CD1   1 
ATOM   1126 C CD2   . LEU A 1 177 ? 124.303 151.670 131.584 1.00 133.82 ? 177 LEU A CD2   1 
ATOM   1127 N N     . THR A 1 178 ? 125.571 155.291 130.722 1.00 138.59 ? 178 THR A N     1 
ATOM   1128 C CA    . THR A 1 178 ? 125.192 155.758 129.397 1.00 140.94 ? 178 THR A CA    1 
ATOM   1129 C C     . THR A 1 178 ? 124.573 154.628 128.580 1.00 149.10 ? 178 THR A C     1 
ATOM   1130 O O     . THR A 1 178 ? 124.892 153.449 128.760 1.00 148.33 ? 178 THR A O     1 
ATOM   1131 C CB    . THR A 1 178 ? 126.407 156.331 128.663 1.00 135.82 ? 178 THR A CB    1 
ATOM   1132 O OG1   . THR A 1 178 ? 126.027 156.729 127.339 1.00 143.95 ? 178 THR A OG1   1 
ATOM   1133 C CG2   . THR A 1 178 ? 127.520 155.296 128.578 1.00 130.50 ? 178 THR A CG2   1 
ATOM   1134 N N     . ALA A 1 179 ? 123.668 155.002 127.677 1.00 153.62 ? 179 ALA A N     1 
ATOM   1135 C CA    . ALA A 1 179 ? 122.999 154.061 126.792 1.00 153.65 ? 179 ALA A CA    1 
ATOM   1136 C C     . ALA A 1 179 ? 122.809 154.722 125.434 1.00 154.48 ? 179 ALA A C     1 
ATOM   1137 O O     . ALA A 1 179 ? 123.063 155.916 125.261 1.00 154.01 ? 179 ALA A O     1 
ATOM   1138 C CB    . ALA A 1 179 ? 121.655 153.598 127.369 1.00 149.08 ? 179 ALA A CB    1 
ATOM   1139 N N     . ASN A 1 180 ? 122.365 153.932 124.460 1.00 155.15 ? 180 ASN A N     1 
ATOM   1140 C CA    . ASN A 1 180 ? 122.167 154.412 123.100 1.00 155.68 ? 180 ASN A CA    1 
ATOM   1141 C C     . ASN A 1 180 ? 120.750 154.114 122.628 1.00 155.70 ? 180 ASN A C     1 
ATOM   1142 O O     . ASN A 1 180 ? 120.137 153.119 123.026 1.00 155.73 ? 180 ASN A O     1 
ATOM   1143 C CB    . ASN A 1 180 ? 123.186 153.793 122.141 1.00 152.75 ? 180 ASN A CB    1 
ATOM   1144 C CG    . ASN A 1 180 ? 124.572 154.375 122.318 1.00 152.90 ? 180 ASN A CG    1 
ATOM   1145 O OD1   . ASN A 1 180 ? 125.320 153.964 123.202 1.00 154.66 ? 180 ASN A OD1   1 
ATOM   1146 N ND2   . ASN A 1 180 ? 124.918 155.346 121.482 1.00 150.85 ? 180 ASN A ND2   1 
ATOM   1147 N N     . ILE A 1 181 ? 120.242 154.994 121.774 1.00 154.93 ? 181 ILE A N     1 
ATOM   1148 C CA    . ILE A 1 181 ? 118.855 154.967 121.328 1.00 154.05 ? 181 ILE A CA    1 
ATOM   1149 C C     . ILE A 1 181 ? 118.755 154.222 120.004 1.00 151.99 ? 181 ILE A C     1 
ATOM   1150 O O     . ILE A 1 181 ? 119.615 154.363 119.126 1.00 153.81 ? 181 ILE A O     1 
ATOM   1151 C CB    . ILE A 1 181 ? 118.301 156.401 121.204 1.00 157.44 ? 181 ILE A CB    1 
ATOM   1152 C CG1   . ILE A 1 181 ? 118.155 157.051 122.583 1.00 156.64 ? 181 ILE A CG1   1 
ATOM   1153 C CG2   . ILE A 1 181 ? 116.972 156.409 120.470 1.00 157.75 ? 181 ILE A CG2   1 
ATOM   1154 C CD1   . ILE A 1 181 ? 119.385 157.804 123.049 1.00 155.14 ? 181 ILE A CD1   1 
ATOM   1155 N N     . GLN A 1 182 ? 117.701 153.420 119.863 1.00 150.33 ? 182 GLN A N     1 
ATOM   1156 C CA    . GLN A 1 182 ? 117.342 152.756 118.617 1.00 154.12 ? 182 GLN A CA    1 
ATOM   1157 C C     . GLN A 1 182 ? 116.262 153.506 117.847 1.00 155.68 ? 182 GLN A C     1 
ATOM   1158 O O     . GLN A 1 182 ? 116.299 153.540 116.614 1.00 157.46 ? 182 GLN A O     1 
ATOM   1159 C CB    . GLN A 1 182 ? 116.873 151.325 118.908 1.00 154.56 ? 182 GLN A CB    1 
ATOM   1160 C CG    . GLN A 1 182 ? 116.410 150.539 117.692 1.00 158.00 ? 182 GLN A CG    1 
ATOM   1161 C CD    . GLN A 1 182 ? 116.000 149.120 118.041 1.00 158.61 ? 182 GLN A CD    1 
ATOM   1162 O OE1   . GLN A 1 182 ? 116.396 148.585 119.076 1.00 155.62 ? 182 GLN A OE1   1 
ATOM   1163 N NE2   . GLN A 1 182 ? 115.200 148.506 117.178 1.00 161.22 ? 182 GLN A NE2   1 
ATOM   1164 N N     . HIS A 1 183 ? 115.304 154.114 118.547 1.00 154.20 ? 183 HIS A N     1 
ATOM   1165 C CA    . HIS A 1 183 ? 114.259 154.898 117.902 1.00 158.81 ? 183 HIS A CA    1 
ATOM   1166 C C     . HIS A 1 183 ? 113.687 155.889 118.907 1.00 158.09 ? 183 HIS A C     1 
ATOM   1167 O O     . HIS A 1 183 ? 113.744 155.664 120.119 1.00 154.73 ? 183 HIS A O     1 
ATOM   1168 C CB    . HIS A 1 183 ? 113.149 154.001 117.342 1.00 160.62 ? 183 HIS A CB    1 
ATOM   1169 C CG    . HIS A 1 183 ? 112.069 154.750 116.625 1.00 161.16 ? 183 HIS A CG    1 
ATOM   1170 N ND1   . HIS A 1 183 ? 112.331 155.629 115.596 1.00 163.71 ? 183 HIS A ND1   1 
ATOM   1171 C CD2   . HIS A 1 183 ? 110.726 154.756 116.791 1.00 159.04 ? 183 HIS A CD2   1 
ATOM   1172 C CE1   . HIS A 1 183 ? 111.196 156.143 115.158 1.00 162.26 ? 183 HIS A CE1   1 
ATOM   1173 N NE2   . HIS A 1 183 ? 110.206 155.629 115.867 1.00 160.80 ? 183 HIS A NE2   1 
ATOM   1174 N N     . ILE A 1 184 ? 113.134 156.985 118.388 1.00 160.90 ? 184 ILE A N     1 
ATOM   1175 C CA    . ILE A 1 184 ? 112.514 158.030 119.198 1.00 161.10 ? 184 ILE A CA    1 
ATOM   1176 C C     . ILE A 1 184 ? 111.120 158.308 118.651 1.00 163.41 ? 184 ILE A C     1 
ATOM   1177 O O     . ILE A 1 184 ? 110.942 158.444 117.435 1.00 163.66 ? 184 ILE A O     1 
ATOM   1178 C CB    . ILE A 1 184 ? 113.353 159.323 119.211 1.00 159.57 ? 184 ILE A CB    1 
ATOM   1179 C CG1   . ILE A 1 184 ? 114.731 159.062 119.816 1.00 159.11 ? 184 ILE A CG1   1 
ATOM   1180 C CG2   . ILE A 1 184 ? 112.639 160.416 119.990 1.00 157.74 ? 184 ILE A CG2   1 
ATOM   1181 C CD1   . ILE A 1 184 ? 115.594 160.298 119.931 1.00 160.99 ? 184 ILE A CD1   1 
ATOM   1182 N N     . SER A 1 185 ? 110.137 158.392 119.545 1.00 161.78 ? 185 SER A N     1 
ATOM   1183 C CA    . SER A 1 185 ? 108.757 158.687 119.188 1.00 161.71 ? 185 SER A CA    1 
ATOM   1184 C C     . SER A 1 185 ? 108.381 160.080 119.676 1.00 161.21 ? 185 SER A C     1 
ATOM   1185 O O     . SER A 1 185 ? 108.747 160.478 120.786 1.00 158.31 ? 185 SER A O     1 
ATOM   1186 C CB    . SER A 1 185 ? 107.801 157.649 119.783 1.00 160.76 ? 185 SER A CB    1 
ATOM   1187 O OG    . SER A 1 185 ? 106.467 157.887 119.368 1.00 163.12 ? 185 SER A OG    1 
ATOM   1188 N N     . GLN A 1 186 ? 107.652 160.818 118.839 1.00 164.21 ? 186 GLN A N     1 
ATOM   1189 C CA    . GLN A 1 186 ? 107.279 162.198 119.112 1.00 163.40 ? 186 GLN A CA    1 
ATOM   1190 C C     . GLN A 1 186 ? 105.801 162.294 119.493 1.00 163.12 ? 186 GLN A C     1 
ATOM   1191 O O     . GLN A 1 186 ? 105.060 161.308 119.487 1.00 161.72 ? 186 GLN A O     1 
ATOM   1192 C CB    . GLN A 1 186 ? 107.587 163.085 117.902 1.00 159.46 ? 186 GLN A CB    1 
ATOM   1193 C CG    . GLN A 1 186 ? 109.041 163.064 117.450 1.00 157.36 ? 186 GLN A CG    1 
ATOM   1194 C CD    . GLN A 1 186 ? 109.363 161.885 116.549 1.00 160.53 ? 186 GLN A CD    1 
ATOM   1195 O OE1   . GLN A 1 186 ? 108.464 161.221 116.032 1.00 161.33 ? 186 GLN A OE1   1 
ATOM   1196 N NE2   . GLN A 1 186 ? 110.649 161.620 116.359 1.00 160.89 ? 186 GLN A NE2   1 
ATOM   1197 N N     . GLY A 1 187 ? 105.372 163.504 119.831 1.00 161.17 ? 187 GLY A N     1 
ATOM   1198 C CA    . GLY A 1 187 ? 103.974 163.770 120.129 1.00 159.34 ? 187 GLY A CA    1 
ATOM   1199 C C     . GLY A 1 187 ? 103.702 163.737 121.629 1.00 159.86 ? 187 GLY A C     1 
ATOM   1200 O O     . GLY A 1 187 ? 104.424 164.355 122.411 1.00 158.31 ? 187 GLY A O     1 
ATOM   1201 N N     . SER A 1 188 ? 102.645 163.019 122.022 1.00 161.75 ? 188 SER A N     1 
ATOM   1202 C CA    . SER A 1 188 ? 102.384 162.727 123.423 1.00 159.70 ? 188 SER A CA    1 
ATOM   1203 C C     . SER A 1 188 ? 103.616 162.061 124.043 1.00 159.21 ? 188 SER A C     1 
ATOM   1204 O O     . SER A 1 188 ? 104.509 161.623 123.314 1.00 160.76 ? 188 SER A O     1 
ATOM   1205 C CB    . SER A 1 188 ? 101.150 161.829 123.536 1.00 161.18 ? 188 SER A CB    1 
ATOM   1206 O OG    . SER A 1 188 ? 99.987  162.509 123.093 1.00 159.90 ? 188 SER A OG    1 
ATOM   1207 N N     . PRO A 1 189 ? 103.687 161.965 125.410 1.00 155.50 ? 189 PRO A N     1 
ATOM   1208 C CA    . PRO A 1 189 ? 104.943 161.550 126.060 1.00 155.43 ? 189 PRO A CA    1 
ATOM   1209 C C     . PRO A 1 189 ? 105.673 160.431 125.335 1.00 157.80 ? 189 PRO A C     1 
ATOM   1210 O O     . PRO A 1 189 ? 105.164 159.315 125.187 1.00 158.96 ? 189 PRO A O     1 
ATOM   1211 C CB    . PRO A 1 189 ? 104.473 161.110 127.449 1.00 152.94 ? 189 PRO A CB    1 
ATOM   1212 C CG    . PRO A 1 189 ? 103.348 162.041 127.739 1.00 152.85 ? 189 PRO A CG    1 
ATOM   1213 C CD    . PRO A 1 189 ? 102.672 162.342 126.414 1.00 152.44 ? 189 PRO A CD    1 
ATOM   1214 N N     . GLY A 1 190 ? 106.882 160.748 124.880 1.00 158.53 ? 190 GLY A N     1 
ATOM   1215 C CA    . GLY A 1 190 ? 107.498 159.977 123.816 1.00 157.04 ? 190 GLY A CA    1 
ATOM   1216 C C     . GLY A 1 190 ? 107.980 158.617 124.284 1.00 156.86 ? 190 GLY A C     1 
ATOM   1217 O O     . GLY A 1 190 ? 108.491 158.458 125.393 1.00 157.06 ? 190 GLY A O     1 
ATOM   1218 N N     . ILE A 1 191 ? 107.818 157.629 123.414 1.00 155.15 ? 191 ILE A N     1 
ATOM   1219 C CA    . ILE A 1 191 ? 108.325 156.286 123.652 1.00 155.59 ? 191 ILE A CA    1 
ATOM   1220 C C     . ILE A 1 191 ? 109.765 156.222 123.167 1.00 152.54 ? 191 ILE A C     1 
ATOM   1221 O O     . ILE A 1 191 ? 110.061 156.568 122.017 1.00 148.83 ? 191 ILE A O     1 
ATOM   1222 C CB    . ILE A 1 191 ? 107.454 155.235 122.945 1.00 155.41 ? 191 ILE A CB    1 
ATOM   1223 C CG1   . ILE A 1 191 ? 106.046 155.223 123.543 1.00 153.99 ? 191 ILE A CG1   1 
ATOM   1224 C CG2   . ILE A 1 191 ? 108.095 153.857 123.035 1.00 155.76 ? 191 ILE A CG2   1 
ATOM   1225 C CD1   . ILE A 1 191 ? 106.017 154.929 125.028 1.00 158.35 ? 191 ILE A CD1   1 
ATOM   1226 N N     . LEU A 1 192 ? 110.663 155.791 124.046 1.00 154.89 ? 192 LEU A N     1 
ATOM   1227 C CA    . LEU A 1 192 ? 112.065 155.609 123.707 1.00 152.50 ? 192 LEU A CA    1 
ATOM   1228 C C     . LEU A 1 192 ? 112.353 154.128 123.521 1.00 152.38 ? 192 LEU A C     1 
ATOM   1229 O O     . LEU A 1 192 ? 112.043 153.314 124.397 1.00 156.18 ? 192 LEU A O     1 
ATOM   1230 C CB    . LEU A 1 192 ? 112.982 156.183 124.789 1.00 153.38 ? 192 LEU A CB    1 
ATOM   1231 C CG    . LEU A 1 192 ? 113.309 157.675 124.737 1.00 150.82 ? 192 LEU A CG    1 
ATOM   1232 C CD1   . LEU A 1 192 ? 114.459 157.987 125.681 1.00 145.16 ? 192 LEU A CD1   1 
ATOM   1233 C CD2   . LEU A 1 192 ? 113.644 158.107 123.318 1.00 152.03 ? 192 LEU A CD2   1 
ATOM   1234 N N     . THR A 1 193 ? 112.941 153.788 122.384 1.00 149.32 ? 193 THR A N     1 
ATOM   1235 C CA    . THR A 1 193 ? 113.449 152.450 122.136 1.00 149.66 ? 193 THR A CA    1 
ATOM   1236 C C     . THR A 1 193 ? 114.962 152.479 122.283 1.00 145.83 ? 193 THR A C     1 
ATOM   1237 O O     . THR A 1 193 ? 115.620 153.409 121.814 1.00 146.50 ? 193 THR A O     1 
ATOM   1238 C CB    . THR A 1 193 ? 113.058 151.959 120.740 1.00 154.91 ? 193 THR A CB    1 
ATOM   1239 O OG1   . THR A 1 193 ? 111.640 152.079 120.570 1.00 157.61 ? 193 THR A OG1   1 
ATOM   1240 C CG2   . THR A 1 193 ? 113.461 150.505 120.551 1.00 154.59 ? 193 THR A CG2   1 
ATOM   1241 N N     . LEU A 1 194 ? 115.511 151.468 122.945 1.00 143.80 ? 194 LEU A N     1 
ATOM   1242 C CA    . LEU A 1 194 ? 116.938 151.422 123.217 1.00 145.76 ? 194 LEU A CA    1 
ATOM   1243 C C     . LEU A 1 194 ? 117.542 150.139 122.665 1.00 146.89 ? 194 LEU A C     1 
ATOM   1244 O O     . LEU A 1 194 ? 116.849 149.139 122.456 1.00 148.92 ? 194 LEU A O     1 
ATOM   1245 C CB    . LEU A 1 194 ? 117.217 151.536 124.719 1.00 148.01 ? 194 LEU A CB    1 
ATOM   1246 C CG    . LEU A 1 194 ? 116.685 152.813 125.371 1.00 152.42 ? 194 LEU A CG    1 
ATOM   1247 C CD1   . LEU A 1 194 ? 117.045 152.850 126.841 1.00 153.12 ? 194 LEU A CD1   1 
ATOM   1248 C CD2   . LEU A 1 194 ? 117.217 154.047 124.656 1.00 154.49 ? 194 LEU A CD2   1 
ATOM   1249 N N     . ARG A 1 195 ? 118.848 150.189 122.420 1.00 148.70 ? 195 ARG A N     1 
ATOM   1250 C CA    . ARG A 1 195 ? 119.593 149.042 121.914 1.00 149.34 ? 195 ARG A CA    1 
ATOM   1251 C C     . ARG A 1 195 ? 119.467 147.841 122.846 1.00 147.51 ? 195 ARG A C     1 
ATOM   1252 O O     . ARG A 1 195 ? 119.658 147.961 124.056 1.00 147.80 ? 195 ARG A O     1 
ATOM   1253 C CB    . ARG A 1 195 ? 121.069 149.403 121.728 1.00 149.86 ? 195 ARG A CB    1 
ATOM   1254 C CG    . ARG A 1 195 ? 121.345 150.371 120.587 1.00 147.81 ? 195 ARG A CG    1 
ATOM   1255 C CD    . ARG A 1 195 ? 121.099 149.716 119.237 1.00 148.84 ? 195 ARG A CD    1 
ATOM   1256 N NE    . ARG A 1 195 ? 121.533 150.562 118.131 1.00 151.55 ? 195 ARG A NE    1 
ATOM   1257 C CZ    . ARG A 1 195 ? 122.758 150.561 117.623 1.00 149.55 ? 195 ARG A CZ    1 
ATOM   1258 N NH1   . ARG A 1 195 ? 123.704 149.769 118.101 1.00 149.59 ? 195 ARG A NH1   1 
ATOM   1259 N NH2   . ARG A 1 195 ? 123.042 151.374 116.610 1.00 147.78 ? 195 ARG A NH2   1 
ATOM   1260 N N     . HIS A 1 201 ? 121.608 148.353 130.783 1.00 141.18 ? 201 HIS A N     1 
ATOM   1261 C CA    . HIS A 1 201 ? 121.095 149.632 131.256 1.00 142.02 ? 201 HIS A CA    1 
ATOM   1262 C C     . HIS A 1 201 ? 119.801 149.457 132.048 1.00 139.43 ? 201 HIS A C     1 
ATOM   1263 O O     . HIS A 1 201 ? 119.029 148.526 131.809 1.00 138.04 ? 201 HIS A O     1 
ATOM   1264 C CB    . HIS A 1 201 ? 120.875 150.589 130.079 1.00 146.87 ? 201 HIS A CB    1 
ATOM   1265 C CG    . HIS A 1 201 ? 120.188 149.964 128.904 1.00 148.87 ? 201 HIS A CG    1 
ATOM   1266 N ND1   . HIS A 1 201 ? 118.855 149.619 128.914 1.00 148.07 ? 201 HIS A ND1   1 
ATOM   1267 C CD2   . HIS A 1 201 ? 120.652 149.629 127.677 1.00 147.48 ? 201 HIS A CD2   1 
ATOM   1268 C CE1   . HIS A 1 201 ? 118.528 149.096 127.745 1.00 146.27 ? 201 HIS A CE1   1 
ATOM   1269 N NE2   . HIS A 1 201 ? 119.600 149.091 126.976 1.00 146.21 ? 201 HIS A NE2   1 
ATOM   1270 N N     . HIS A 1 202 ? 119.575 150.365 132.994 1.00 139.30 ? 202 HIS A N     1 
ATOM   1271 C CA    . HIS A 1 202 ? 118.387 150.350 133.833 1.00 139.31 ? 202 HIS A CA    1 
ATOM   1272 C C     . HIS A 1 202 ? 117.963 151.786 134.096 1.00 140.40 ? 202 HIS A C     1 
ATOM   1273 O O     . HIS A 1 202 ? 118.789 152.702 134.080 1.00 142.55 ? 202 HIS A O     1 
ATOM   1274 C CB    . HIS A 1 202 ? 118.635 149.616 135.158 1.00 141.26 ? 202 HIS A CB    1 
ATOM   1275 C CG    . HIS A 1 202 ? 119.922 149.991 135.823 1.00 145.83 ? 202 HIS A CG    1 
ATOM   1276 N ND1   . HIS A 1 202 ? 120.220 151.284 136.197 1.00 149.91 ? 202 HIS A ND1   1 
ATOM   1277 C CD2   . HIS A 1 202 ? 120.994 149.242 136.171 1.00 145.06 ? 202 HIS A CD2   1 
ATOM   1278 C CE1   . HIS A 1 202 ? 121.420 151.315 136.751 1.00 149.03 ? 202 HIS A CE1   1 
ATOM   1279 N NE2   . HIS A 1 202 ? 121.911 150.088 136.749 1.00 148.80 ? 202 HIS A NE2   1 
ATOM   1280 N N     . PHE A 1 203 ? 116.666 151.977 134.332 1.00 138.75 ? 203 PHE A N     1 
ATOM   1281 C CA    . PHE A 1 203 ? 116.109 153.306 134.547 1.00 140.99 ? 203 PHE A CA    1 
ATOM   1282 C C     . PHE A 1 203 ? 115.026 153.240 135.615 1.00 140.02 ? 203 PHE A C     1 
ATOM   1283 O O     . PHE A 1 203 ? 114.459 152.179 135.889 1.00 139.91 ? 203 PHE A O     1 
ATOM   1284 C CB    . PHE A 1 203 ? 115.539 153.893 133.247 1.00 145.83 ? 203 PHE A CB    1 
ATOM   1285 C CG    . PHE A 1 203 ? 116.535 153.960 132.123 1.00 145.54 ? 203 PHE A CG    1 
ATOM   1286 C CD1   . PHE A 1 203 ? 116.689 152.893 131.253 1.00 143.23 ? 203 PHE A CD1   1 
ATOM   1287 C CD2   . PHE A 1 203 ? 117.313 155.091 131.933 1.00 147.12 ? 203 PHE A CD2   1 
ATOM   1288 C CE1   . PHE A 1 203 ? 117.606 152.948 130.221 1.00 140.08 ? 203 PHE A CE1   1 
ATOM   1289 C CE2   . PHE A 1 203 ? 118.231 155.154 130.898 1.00 147.19 ? 203 PHE A CE2   1 
ATOM   1290 C CZ    . PHE A 1 203 ? 118.377 154.081 130.041 1.00 143.60 ? 203 PHE A CZ    1 
ATOM   1291 N N     . HIS A 1 204 ? 114.737 154.395 136.214 1.00 141.79 ? 204 HIS A N     1 
ATOM   1292 C CA    . HIS A 1 204 ? 113.750 154.504 137.278 1.00 146.52 ? 204 HIS A CA    1 
ATOM   1293 C C     . HIS A 1 204 ? 112.831 155.691 137.030 1.00 153.29 ? 204 HIS A C     1 
ATOM   1294 O O     . HIS A 1 204 ? 113.220 156.681 136.405 1.00 154.98 ? 204 HIS A O     1 
ATOM   1295 C CB    . HIS A 1 204 ? 114.419 154.658 138.647 1.00 145.40 ? 204 HIS A CB    1 
ATOM   1296 C CG    . HIS A 1 204 ? 114.790 153.360 139.289 1.00 144.61 ? 204 HIS A CG    1 
ATOM   1297 N ND1   . HIS A 1 204 ? 115.615 153.285 140.391 1.00 143.92 ? 204 HIS A ND1   1 
ATOM   1298 C CD2   . HIS A 1 204 ? 114.436 152.086 138.997 1.00 142.90 ? 204 HIS A CD2   1 
ATOM   1299 C CE1   . HIS A 1 204 ? 115.757 152.020 140.746 1.00 142.51 ? 204 HIS A CE1   1 
ATOM   1300 N NE2   . HIS A 1 204 ? 115.053 151.272 139.916 1.00 140.15 ? 204 HIS A NE2   1 
ATOM   1301 N N     . THR A 1 205 ? 111.607 155.583 137.543 1.00 154.37 ? 205 THR A N     1 
ATOM   1302 C CA    . THR A 1 205 ? 110.653 156.678 137.440 1.00 156.78 ? 205 THR A CA    1 
ATOM   1303 C C     . THR A 1 205 ? 111.139 157.885 138.232 1.00 158.64 ? 205 THR A C     1 
ATOM   1304 O O     . THR A 1 205 ? 111.650 157.755 139.348 1.00 159.74 ? 205 THR A O     1 
ATOM   1305 C CB    . THR A 1 205 ? 109.278 156.238 137.946 1.00 155.19 ? 205 THR A CB    1 
ATOM   1306 O OG1   . THR A 1 205 ? 108.851 155.078 137.221 1.00 154.14 ? 205 THR A OG1   1 
ATOM   1307 C CG2   . THR A 1 205 ? 108.253 157.349 137.750 1.00 157.61 ? 205 THR A CG2   1 
ATOM   1308 N N     . GLY A 1 206 ? 110.973 159.070 137.648 1.00 158.95 ? 206 GLY A N     1 
ATOM   1309 C CA    . GLY A 1 206 ? 111.416 160.300 138.264 1.00 158.14 ? 206 GLY A CA    1 
ATOM   1310 C C     . GLY A 1 206 ? 112.865 160.653 138.018 1.00 153.88 ? 206 GLY A C     1 
ATOM   1311 O O     . GLY A 1 206 ? 113.317 161.705 138.488 1.00 147.85 ? 206 GLY A O     1 
ATOM   1312 N N     . ASP A 1 207 ? 113.608 159.814 137.302 1.00 153.18 ? 207 ASP A N     1 
ATOM   1313 C CA    . ASP A 1 207 ? 115.004 160.094 137.012 1.00 148.71 ? 207 ASP A CA    1 
ATOM   1314 C C     . ASP A 1 207 ? 115.122 161.141 135.910 1.00 147.20 ? 207 ASP A C     1 
ATOM   1315 O O     . ASP A 1 207 ? 114.277 161.231 135.015 1.00 148.11 ? 207 ASP A O     1 
ATOM   1316 C CB    . ASP A 1 207 ? 115.730 158.813 136.599 1.00 146.17 ? 207 ASP A CB    1 
ATOM   1317 C CG    . ASP A 1 207 ? 117.237 158.935 136.707 1.00 146.41 ? 207 ASP A CG    1 
ATOM   1318 O OD1   . ASP A 1 207 ? 117.718 159.923 137.300 1.00 146.11 ? 207 ASP A OD1   1 
ATOM   1319 O OD2   . ASP A 1 207 ? 117.942 158.039 136.198 1.00 147.31 ? 207 ASP A OD2   1 
ATOM   1320 N N     . TRP A 1 208 ? 116.184 161.936 135.984 1.00 140.67 ? 208 TRP A N     1 
ATOM   1321 C CA    . TRP A 1 208 ? 116.462 162.972 134.999 1.00 131.74 ? 208 TRP A CA    1 
ATOM   1322 C C     . TRP A 1 208 ? 117.591 162.510 134.088 1.00 132.37 ? 208 TRP A C     1 
ATOM   1323 O O     . TRP A 1 208 ? 118.638 162.064 134.567 1.00 129.98 ? 208 TRP A O     1 
ATOM   1324 C CB    . TRP A 1 208 ? 116.833 164.289 135.681 1.00 128.92 ? 208 TRP A CB    1 
ATOM   1325 C CG    . TRP A 1 208 ? 115.687 164.945 136.390 1.00 130.41 ? 208 TRP A CG    1 
ATOM   1326 C CD1   . TRP A 1 208 ? 114.403 164.495 136.462 1.00 132.26 ? 208 TRP A CD1   1 
ATOM   1327 C CD2   . TRP A 1 208 ? 115.724 166.173 137.127 1.00 131.15 ? 208 TRP A CD2   1 
ATOM   1328 N NE1   . TRP A 1 208 ? 113.637 165.366 137.199 1.00 132.10 ? 208 TRP A NE1   1 
ATOM   1329 C CE2   . TRP A 1 208 ? 114.425 166.404 137.619 1.00 130.04 ? 208 TRP A CE2   1 
ATOM   1330 C CE3   . TRP A 1 208 ? 116.730 167.099 137.420 1.00 131.69 ? 208 TRP A CE3   1 
ATOM   1331 C CZ2   . TRP A 1 208 ? 114.105 167.523 138.385 1.00 129.78 ? 208 TRP A CZ2   1 
ATOM   1332 C CZ3   . TRP A 1 208 ? 116.411 168.208 138.181 1.00 131.24 ? 208 TRP A CZ3   1 
ATOM   1333 C CH2   . TRP A 1 208 ? 115.109 168.411 138.655 1.00 131.37 ? 208 TRP A CH2   1 
ATOM   1334 N N     . VAL A 1 209 ? 117.370 162.609 132.779 1.00 135.60 ? 209 VAL A N     1 
ATOM   1335 C CA    . VAL A 1 209 ? 118.334 162.159 131.784 1.00 134.48 ? 209 VAL A CA    1 
ATOM   1336 C C     . VAL A 1 209 ? 118.575 163.279 130.784 1.00 136.11 ? 209 VAL A C     1 
ATOM   1337 O O     . VAL A 1 209 ? 117.725 164.151 130.579 1.00 136.35 ? 209 VAL A O     1 
ATOM   1338 C CB    . VAL A 1 209 ? 117.863 160.880 131.057 1.00 137.28 ? 209 VAL A CB    1 
ATOM   1339 C CG1   . VAL A 1 209 ? 117.711 159.731 132.041 1.00 139.99 ? 209 VAL A CG1   1 
ATOM   1340 C CG2   . VAL A 1 209 ? 116.554 161.136 130.324 1.00 140.10 ? 209 VAL A CG2   1 
ATOM   1341 N N     . THR A 1 210 ? 119.751 163.249 130.161 1.00 138.43 ? 210 THR A N     1 
ATOM   1342 C CA    . THR A 1 210 ? 120.128 164.194 129.124 1.00 145.93 ? 210 THR A CA    1 
ATOM   1343 C C     . THR A 1 210 ? 120.586 163.416 127.898 1.00 152.76 ? 210 THR A C     1 
ATOM   1344 O O     . THR A 1 210 ? 120.896 162.223 127.972 1.00 151.65 ? 210 THR A O     1 
ATOM   1345 C CB    . THR A 1 210 ? 121.234 165.149 129.600 1.00 142.19 ? 210 THR A CB    1 
ATOM   1346 O OG1   . THR A 1 210 ? 121.459 166.161 128.610 1.00 147.83 ? 210 THR A OG1   1 
ATOM   1347 C CG2   . THR A 1 210 ? 122.528 164.390 129.845 1.00 139.83 ? 210 THR A CG2   1 
ATOM   1348 N N     . PHE A 1 211 ? 120.618 164.104 126.760 1.00 157.52 ? 211 PHE A N     1 
ATOM   1349 C CA    . PHE A 1 211 ? 120.894 163.481 125.475 1.00 154.67 ? 211 PHE A CA    1 
ATOM   1350 C C     . PHE A 1 211 ? 122.128 164.105 124.840 1.00 153.49 ? 211 PHE A C     1 
ATOM   1351 O O     . PHE A 1 211 ? 122.323 165.323 124.899 1.00 154.71 ? 211 PHE A O     1 
ATOM   1352 C CB    . PHE A 1 211 ? 119.695 163.619 124.534 1.00 154.07 ? 211 PHE A CB    1 
ATOM   1353 C CG    . PHE A 1 211 ? 118.395 163.184 125.145 1.00 153.69 ? 211 PHE A CG    1 
ATOM   1354 C CD1   . PHE A 1 211 ? 118.024 161.851 125.139 1.00 151.92 ? 211 PHE A CD1   1 
ATOM   1355 C CD2   . PHE A 1 211 ? 117.543 164.109 125.724 1.00 152.15 ? 211 PHE A CD2   1 
ATOM   1356 C CE1   . PHE A 1 211 ? 116.828 161.447 125.701 1.00 149.09 ? 211 PHE A CE1   1 
ATOM   1357 C CE2   . PHE A 1 211 ? 116.346 163.712 126.288 1.00 150.97 ? 211 PHE A CE2   1 
ATOM   1358 C CZ    . PHE A 1 211 ? 115.988 162.379 126.276 1.00 149.58 ? 211 PHE A CZ    1 
ATOM   1359 N N     . SER A 1 212 ? 122.957 163.259 124.231 1.00 151.73 ? 212 SER A N     1 
ATOM   1360 C CA    . SER A 1 212 ? 124.163 163.694 123.544 1.00 151.87 ? 212 SER A CA    1 
ATOM   1361 C C     . SER A 1 212 ? 124.298 162.927 122.237 1.00 157.65 ? 212 SER A C     1 
ATOM   1362 O O     . SER A 1 212 ? 123.864 161.777 122.127 1.00 160.11 ? 212 SER A O     1 
ATOM   1363 C CB    . SER A 1 212 ? 125.414 163.486 124.408 1.00 144.39 ? 212 SER A CB    1 
ATOM   1364 O OG    . SER A 1 212 ? 126.586 163.871 123.712 1.00 139.44 ? 212 SER A OG    1 
ATOM   1365 N N     . GLY A 1 213 ? 124.911 163.574 121.250 1.00 158.55 ? 213 GLY A N     1 
ATOM   1366 C CA    . GLY A 1 213 ? 125.093 162.953 119.947 1.00 160.73 ? 213 GLY A CA    1 
ATOM   1367 C C     . GLY A 1 213 ? 123.798 162.634 119.233 1.00 163.95 ? 213 GLY A C     1 
ATOM   1368 O O     . GLY A 1 213 ? 123.701 161.602 118.558 1.00 161.51 ? 213 GLY A O     1 
ATOM   1369 N N     . ILE A 1 214 ? 122.798 163.500 119.364 1.00 164.11 ? 214 ILE A N     1 
ATOM   1370 C CA    . ILE A 1 214 ? 121.485 163.274 118.770 1.00 161.93 ? 214 ILE A CA    1 
ATOM   1371 C C     . ILE A 1 214 ? 121.460 163.894 117.379 1.00 163.65 ? 214 ILE A C     1 
ATOM   1372 O O     . ILE A 1 214 ? 121.749 165.084 117.214 1.00 165.96 ? 214 ILE A O     1 
ATOM   1373 C CB    . ILE A 1 214 ? 120.371 163.859 119.650 1.00 159.54 ? 214 ILE A CB    1 
ATOM   1374 C CG1   . ILE A 1 214 ? 120.375 163.201 121.030 1.00 159.62 ? 214 ILE A CG1   1 
ATOM   1375 C CG2   . ILE A 1 214 ? 119.019 163.677 118.982 1.00 160.90 ? 214 ILE A CG2   1 
ATOM   1376 C CD1   . ILE A 1 214 ? 119.897 161.768 121.026 1.00 158.75 ? 214 ILE A CD1   1 
ATOM   1377 N N     . GLU A 1 215 ? 121.113 163.091 116.378 1.00 161.42 ? 215 GLU A N     1 
ATOM   1378 C CA    . GLU A 1 215 ? 120.915 163.575 115.021 1.00 158.29 ? 215 GLU A CA    1 
ATOM   1379 C C     . GLU A 1 215 ? 119.431 163.814 114.771 1.00 158.44 ? 215 GLU A C     1 
ATOM   1380 O O     . GLU A 1 215 ? 118.571 163.103 115.297 1.00 159.48 ? 215 GLU A O     1 
ATOM   1381 C CB    . GLU A 1 215 ? 121.469 162.586 113.993 1.00 157.60 ? 215 GLU A CB    1 
ATOM   1382 C CG    . GLU A 1 215 ? 122.959 162.317 114.133 1.00 159.08 ? 215 GLU A CG    1 
ATOM   1383 C CD    . GLU A 1 215 ? 123.540 161.600 112.930 1.00 161.24 ? 215 GLU A CD    1 
ATOM   1384 O OE1   . GLU A 1 215 ? 122.993 161.760 111.818 1.00 164.39 ? 215 GLU A OE1   1 
ATOM   1385 O OE2   . GLU A 1 215 ? 124.544 160.875 113.095 1.00 157.93 ? 215 GLU A OE2   1 
ATOM   1386 N N     . GLY A 1 216 ? 119.139 164.826 113.960 1.00 158.48 ? 216 GLY A N     1 
ATOM   1387 C CA    . GLY A 1 216 ? 117.766 165.237 113.747 1.00 156.88 ? 216 GLY A CA    1 
ATOM   1388 C C     . GLY A 1 216 ? 117.323 166.239 114.792 1.00 159.83 ? 216 GLY A C     1 
ATOM   1389 O O     . GLY A 1 216 ? 117.048 167.400 114.474 1.00 161.69 ? 216 GLY A O     1 
ATOM   1390 N N     . MET A 1 217 ? 117.251 165.799 116.047 1.00 160.80 ? 217 MET A N     1 
ATOM   1391 C CA    . MET A 1 217 ? 116.947 166.692 117.165 1.00 162.69 ? 217 MET A CA    1 
ATOM   1392 C C     . MET A 1 217 ? 118.248 167.308 117.681 1.00 165.28 ? 217 MET A C     1 
ATOM   1393 O O     . MET A 1 217 ? 118.755 166.982 118.756 1.00 166.95 ? 217 MET A O     1 
ATOM   1394 C CB    . MET A 1 217 ? 116.207 165.944 118.267 1.00 163.73 ? 217 MET A CB    1 
ATOM   1395 C CG    . MET A 1 217 ? 115.038 165.097 117.797 1.00 164.77 ? 217 MET A CG    1 
ATOM   1396 S SD    . MET A 1 217 ? 115.528 163.422 117.346 1.00 169.44 ? 217 MET A SD    1 
ATOM   1397 C CE    . MET A 1 217 ? 113.942 162.595 117.373 1.00 165.13 ? 217 MET A CE    1 
ATOM   1398 N N     . VAL A 1 218 ? 118.794 168.221 116.873 1.00 167.27 ? 218 VAL A N     1 
ATOM   1399 C CA    . VAL A 1 218 ? 120.058 168.862 117.217 1.00 168.97 ? 218 VAL A CA    1 
ATOM   1400 C C     . VAL A 1 218 ? 119.932 169.734 118.459 1.00 168.31 ? 218 VAL A C     1 
ATOM   1401 O O     . VAL A 1 218 ? 120.940 170.038 119.105 1.00 167.90 ? 218 VAL A O     1 
ATOM   1402 C CB    . VAL A 1 218 ? 120.589 169.682 116.021 1.00 167.16 ? 218 VAL A CB    1 
ATOM   1403 C CG1   . VAL A 1 218 ? 120.878 168.770 114.838 1.00 163.46 ? 218 VAL A CG1   1 
ATOM   1404 C CG2   . VAL A 1 218 ? 119.599 170.771 115.634 1.00 164.85 ? 218 VAL A CG2   1 
ATOM   1405 N N     . GLU A 1 219 ? 118.714 170.147 118.812 1.00 166.67 ? 219 GLU A N     1 
ATOM   1406 C CA    . GLU A 1 219 ? 118.509 170.974 119.994 1.00 165.38 ? 219 GLU A CA    1 
ATOM   1407 C C     . GLU A 1 219 ? 118.607 170.184 121.293 1.00 166.19 ? 219 GLU A C     1 
ATOM   1408 O O     . GLU A 1 219 ? 118.763 170.790 122.359 1.00 167.30 ? 219 GLU A O     1 
ATOM   1409 C CB    . GLU A 1 219 ? 117.149 171.676 119.921 1.00 163.26 ? 219 GLU A CB    1 
ATOM   1410 C CG    . GLU A 1 219 ? 115.945 170.743 119.986 1.00 163.04 ? 219 GLU A CG    1 
ATOM   1411 C CD    . GLU A 1 219 ? 115.387 170.391 118.617 1.00 161.48 ? 219 GLU A CD    1 
ATOM   1412 O OE1   . GLU A 1 219 ? 116.177 170.101 117.696 1.00 159.69 ? 219 GLU A OE1   1 
ATOM   1413 O OE2   . GLU A 1 219 ? 114.148 170.412 118.460 1.00 161.69 ? 219 GLU A OE2   1 
ATOM   1414 N N     . LEU A 1 220 ? 118.519 168.854 121.232 1.00 165.58 ? 220 LEU A N     1 
ATOM   1415 C CA    . LEU A 1 220 ? 118.584 168.029 122.432 1.00 164.64 ? 220 LEU A CA    1 
ATOM   1416 C C     . LEU A 1 220 ? 120.006 167.795 122.925 1.00 164.48 ? 220 LEU A C     1 
ATOM   1417 O O     . LEU A 1 220 ? 120.178 167.242 124.017 1.00 164.34 ? 220 LEU A O     1 
ATOM   1418 C CB    . LEU A 1 220 ? 117.904 166.680 122.184 1.00 162.97 ? 220 LEU A CB    1 
ATOM   1419 C CG    . LEU A 1 220 ? 116.395 166.718 121.933 1.00 161.96 ? 220 LEU A CG    1 
ATOM   1420 C CD1   . LEU A 1 220 ? 115.824 165.309 121.873 1.00 160.58 ? 220 LEU A CD1   1 
ATOM   1421 C CD2   . LEU A 1 220 ? 115.696 167.539 123.003 1.00 157.94 ? 220 LEU A CD2   1 
ATOM   1422 N N     . ASN A 1 221 ? 121.019 168.188 122.158 1.00 164.18 ? 221 ASN A N     1 
ATOM   1423 C CA    . ASN A 1 221 ? 122.406 168.013 122.578 1.00 164.11 ? 221 ASN A CA    1 
ATOM   1424 C C     . ASN A 1 221 ? 122.709 168.961 123.732 1.00 162.72 ? 221 ASN A C     1 
ATOM   1425 O O     . ASN A 1 221 ? 122.714 170.184 123.558 1.00 162.42 ? 221 ASN A O     1 
ATOM   1426 C CB    . ASN A 1 221 ? 123.350 168.260 121.405 1.00 162.55 ? 221 ASN A CB    1 
ATOM   1427 C CG    . ASN A 1 221 ? 123.219 167.208 120.321 1.00 159.68 ? 221 ASN A CG    1 
ATOM   1428 O OD1   . ASN A 1 221 ? 123.851 166.155 120.384 1.00 156.46 ? 221 ASN A OD1   1 
ATOM   1429 N ND2   . ASN A 1 221 ? 122.397 167.491 119.318 1.00 161.77 ? 221 ASN A ND2   1 
ATOM   1430 N N     . GLY A 1 222 ? 122.962 168.400 124.913 1.00 158.89 ? 222 GLY A N     1 
ATOM   1431 C CA    . GLY A 1 222 ? 123.241 169.214 126.078 1.00 157.54 ? 222 GLY A CA    1 
ATOM   1432 C C     . GLY A 1 222 ? 122.047 169.951 126.636 1.00 160.73 ? 222 GLY A C     1 
ATOM   1433 O O     . GLY A 1 222 ? 122.220 170.959 127.325 1.00 159.44 ? 222 GLY A O     1 
ATOM   1434 N N     . CYS A 1 223 ? 120.835 169.477 126.359 1.00 162.81 ? 223 CYS A N     1 
ATOM   1435 C CA    . CYS A 1 223 ? 119.637 170.138 126.848 1.00 162.46 ? 223 CYS A CA    1 
ATOM   1436 C C     . CYS A 1 223 ? 119.457 169.885 128.344 1.00 161.60 ? 223 CYS A C     1 
ATOM   1437 O O     . CYS A 1 223 ? 120.143 169.060 128.954 1.00 160.69 ? 223 CYS A O     1 
ATOM   1438 C CB    . CYS A 1 223 ? 118.407 169.658 126.078 1.00 162.85 ? 223 CYS A CB    1 
ATOM   1439 S SG    . CYS A 1 223 ? 118.007 167.913 126.326 1.00 170.04 ? 223 CYS A SG    1 
ATOM   1440 N N     . ASP A 1 224 ? 118.517 170.619 128.935 1.00 160.92 ? 224 ASP A N     1 
ATOM   1441 C CA    . ASP A 1 224 ? 118.216 170.443 130.344 1.00 157.69 ? 224 ASP A CA    1 
ATOM   1442 C C     . ASP A 1 224 ? 117.635 169.051 130.591 1.00 151.84 ? 224 ASP A C     1 
ATOM   1443 O O     . ASP A 1 224 ? 116.916 168.511 129.745 1.00 152.86 ? 224 ASP A O     1 
ATOM   1444 C CB    . ASP A 1 224 ? 117.239 171.514 130.828 1.00 159.61 ? 224 ASP A CB    1 
ATOM   1445 C CG    . ASP A 1 224 ? 115.864 171.388 130.195 1.00 160.13 ? 224 ASP A CG    1 
ATOM   1446 O OD1   . ASP A 1 224 ? 115.779 171.125 128.978 1.00 161.38 ? 224 ASP A OD1   1 
ATOM   1447 O OD2   . ASP A 1 224 ? 114.862 171.554 130.922 1.00 159.23 ? 224 ASP A OD2   1 
ATOM   1448 N N     . PRO A 1 225 ? 117.948 168.444 131.736 1.00 145.35 ? 225 PRO A N     1 
ATOM   1449 C CA    . PRO A 1 225 ? 117.477 167.080 132.002 1.00 140.51 ? 225 PRO A CA    1 
ATOM   1450 C C     . PRO A 1 225 ? 115.958 166.996 132.016 1.00 137.77 ? 225 PRO A C     1 
ATOM   1451 O O     . PRO A 1 225 ? 115.264 167.920 132.443 1.00 141.21 ? 225 PRO A O     1 
ATOM   1452 C CB    . PRO A 1 225 ? 118.066 166.764 133.381 1.00 138.46 ? 225 PRO A CB    1 
ATOM   1453 C CG    . PRO A 1 225 ? 119.240 167.680 133.510 1.00 138.86 ? 225 PRO A CG    1 
ATOM   1454 C CD    . PRO A 1 225 ? 118.844 168.936 132.795 1.00 144.25 ? 225 PRO A CD    1 
ATOM   1455 N N     . ARG A 1 226 ? 115.447 165.864 131.538 1.00 133.17 ? 226 ARG A N     1 
ATOM   1456 C CA    . ARG A 1 226 ? 114.016 165.642 131.434 1.00 137.17 ? 226 ARG A CA    1 
ATOM   1457 C C     . ARG A 1 226 ? 113.591 164.477 132.321 1.00 137.16 ? 226 ARG A C     1 
ATOM   1458 O O     . ARG A 1 226 ? 114.348 163.516 132.497 1.00 138.79 ? 226 ARG A O     1 
ATOM   1459 C CB    . ARG A 1 226 ? 113.611 165.350 129.983 1.00 141.55 ? 226 ARG A CB    1 
ATOM   1460 C CG    . ARG A 1 226 ? 114.127 166.368 128.979 1.00 146.13 ? 226 ARG A CG    1 
ATOM   1461 C CD    . ARG A 1 226 ? 113.567 167.753 129.253 1.00 148.87 ? 226 ARG A CD    1 
ATOM   1462 N NE    . ARG A 1 226 ? 114.161 168.761 128.384 1.00 153.23 ? 226 ARG A NE    1 
ATOM   1463 C CZ    . ARG A 1 226 ? 113.696 169.088 127.186 1.00 152.63 ? 226 ARG A CZ    1 
ATOM   1464 N NH1   . ARG A 1 226 ? 112.624 168.503 126.677 1.00 152.66 ? 226 ARG A NH1   1 
ATOM   1465 N NH2   . ARG A 1 226 ? 114.322 170.026 126.481 1.00 151.15 ? 226 ARG A NH2   1 
ATOM   1466 N N     . PRO A 1 227 ? 112.391 164.534 132.894 1.00 136.77 ? 227 PRO A N     1 
ATOM   1467 C CA    . PRO A 1 227 ? 111.916 163.420 133.720 1.00 139.04 ? 227 PRO A CA    1 
ATOM   1468 C C     . PRO A 1 227 ? 111.677 162.169 132.889 1.00 147.99 ? 227 PRO A C     1 
ATOM   1469 O O     . PRO A 1 227 ? 111.396 162.232 131.690 1.00 151.06 ? 227 PRO A O     1 
ATOM   1470 C CB    . PRO A 1 227 ? 110.608 163.952 134.316 1.00 137.18 ? 227 PRO A CB    1 
ATOM   1471 C CG    . PRO A 1 227 ? 110.161 165.005 133.358 1.00 135.50 ? 227 PRO A CG    1 
ATOM   1472 C CD    . PRO A 1 227 ? 111.417 165.637 132.836 1.00 134.03 ? 227 PRO A CD    1 
ATOM   1473 N N     . LEU A 1 228 ? 111.794 161.018 133.549 1.00 151.05 ? 228 LEU A N     1 
ATOM   1474 C CA    . LEU A 1 228 ? 111.712 159.725 132.886 1.00 155.08 ? 228 LEU A CA    1 
ATOM   1475 C C     . LEU A 1 228 ? 110.676 158.850 133.577 1.00 157.09 ? 228 LEU A C     1 
ATOM   1476 O O     . LEU A 1 228 ? 110.465 158.944 134.789 1.00 156.66 ? 228 LEU A O     1 
ATOM   1477 C CB    . LEU A 1 228 ? 113.083 159.023 132.878 1.00 153.68 ? 228 LEU A CB    1 
ATOM   1478 C CG    . LEU A 1 228 ? 113.278 157.761 132.032 1.00 154.53 ? 228 LEU A CG    1 
ATOM   1479 C CD1   . LEU A 1 228 ? 114.696 157.714 131.490 1.00 151.27 ? 228 LEU A CD1   1 
ATOM   1480 C CD2   . LEU A 1 228 ? 112.984 156.503 132.836 1.00 154.33 ? 228 LEU A CD2   1 
ATOM   1481 N N     . HIS A 1 229 ? 110.029 157.996 132.786 1.00 157.66 ? 229 HIS A N     1 
ATOM   1482 C CA    . HIS A 1 229 ? 109.067 157.024 133.282 1.00 157.75 ? 229 HIS A CA    1 
ATOM   1483 C C     . HIS A 1 229 ? 109.369 155.668 132.659 1.00 160.46 ? 229 HIS A C     1 
ATOM   1484 O O     . HIS A 1 229 ? 109.949 155.584 131.573 1.00 160.29 ? 229 HIS A O     1 
ATOM   1485 C CB    . HIS A 1 229 ? 107.623 157.446 132.969 1.00 157.39 ? 229 HIS A CB    1 
ATOM   1486 C CG    . HIS A 1 229 ? 106.586 156.581 133.614 1.00 160.47 ? 229 HIS A CG    1 
ATOM   1487 N ND1   . HIS A 1 229 ? 106.617 156.255 134.952 1.00 160.33 ? 229 HIS A ND1   1 
ATOM   1488 C CD2   . HIS A 1 229 ? 105.488 155.974 133.104 1.00 161.57 ? 229 HIS A CD2   1 
ATOM   1489 C CE1   . HIS A 1 229 ? 105.583 155.484 135.240 1.00 159.56 ? 229 HIS A CE1   1 
ATOM   1490 N NE2   . HIS A 1 229 ? 104.882 155.298 134.136 1.00 159.79 ? 229 HIS A NE2   1 
ATOM   1491 N N     . VAL A 1 230 ? 108.972 154.606 133.355 1.00 162.30 ? 230 VAL A N     1 
ATOM   1492 C CA    . VAL A 1 230 ? 109.297 153.238 132.967 1.00 161.63 ? 230 VAL A CA    1 
ATOM   1493 C C     . VAL A 1 230 ? 108.005 152.484 132.690 1.00 162.53 ? 230 VAL A C     1 
ATOM   1494 O O     . VAL A 1 230 ? 107.071 152.522 133.501 1.00 161.26 ? 230 VAL A O     1 
ATOM   1495 C CB    . VAL A 1 230 ? 110.123 152.523 134.053 1.00 157.40 ? 230 VAL A CB    1 
ATOM   1496 C CG1   . VAL A 1 230 ? 110.519 151.129 133.588 1.00 154.38 ? 230 VAL A CG1   1 
ATOM   1497 C CG2   . VAL A 1 230 ? 111.352 153.344 134.412 1.00 153.42 ? 230 VAL A CG2   1 
ATOM   1498 N N     . ARG A 1 231 ? 107.954 151.803 131.550 1.00 164.34 ? 231 ARG A N     1 
ATOM   1499 C CA    . ARG A 1 231 ? 106.829 150.959 131.177 1.00 165.67 ? 231 ARG A CA    1 
ATOM   1500 C C     . ARG A 1 231 ? 107.191 149.488 131.352 1.00 166.38 ? 231 ARG A C     1 
ATOM   1501 O O     . ARG A 1 231 ? 108.364 149.115 131.432 1.00 165.34 ? 231 ARG A O     1 
ATOM   1502 C CB    . ARG A 1 231 ? 106.400 151.227 129.732 1.00 166.68 ? 231 ARG A CB    1 
ATOM   1503 C CG    . ARG A 1 231 ? 105.847 152.623 129.494 1.00 165.74 ? 231 ARG A CG    1 
ATOM   1504 C CD    . ARG A 1 231 ? 105.510 152.842 128.027 1.00 166.21 ? 231 ARG A CD    1 
ATOM   1505 N NE    . ARG A 1 231 ? 104.478 151.926 127.555 1.00 166.07 ? 231 ARG A NE    1 
ATOM   1506 C CZ    . ARG A 1 231 ? 103.185 152.215 127.506 1.00 167.92 ? 231 ARG A CZ    1 
ATOM   1507 N NH1   . ARG A 1 231 ? 102.725 153.394 127.892 1.00 168.49 ? 231 ARG A NH1   1 
ATOM   1508 N NH2   . ARG A 1 231 ? 102.331 151.299 127.057 1.00 167.32 ? 231 ARG A NH2   1 
ATOM   1509 N N     . GLU A 1 232 ? 106.155 148.647 131.411 1.00 167.14 ? 232 GLU A N     1 
ATOM   1510 C CA    . GLU A 1 232 ? 106.357 147.223 131.653 1.00 167.25 ? 232 GLU A CA    1 
ATOM   1511 C C     . GLU A 1 232 ? 106.978 146.503 130.463 1.00 169.13 ? 232 GLU A C     1 
ATOM   1512 O O     . GLU A 1 232 ? 107.538 145.416 130.639 1.00 168.33 ? 232 GLU A O     1 
ATOM   1513 C CB    . GLU A 1 232 ? 105.030 146.559 132.022 1.00 164.48 ? 232 GLU A CB    1 
ATOM   1514 C CG    . GLU A 1 232 ? 103.955 146.685 130.954 1.00 160.39 ? 232 GLU A CG    1 
ATOM   1515 C CD    . GLU A 1 232 ? 102.689 145.931 131.311 1.00 157.09 ? 232 GLU A CD    1 
ATOM   1516 O OE1   . GLU A 1 232 ? 102.718 145.145 132.281 1.00 160.01 ? 232 GLU A OE1   1 
ATOM   1517 O OE2   . GLU A 1 232 ? 101.666 146.125 130.622 1.00 150.02 ? 232 GLU A OE2   1 
ATOM   1518 N N     . ASP A 1 233 ? 106.894 147.074 129.264 1.00 170.35 ? 233 ASP A N     1 
ATOM   1519 C CA    . ASP A 1 233 ? 107.408 146.433 128.061 1.00 169.04 ? 233 ASP A CA    1 
ATOM   1520 C C     . ASP A 1 233 ? 108.867 146.770 127.777 1.00 168.10 ? 233 ASP A C     1 
ATOM   1521 O O     . ASP A 1 233 ? 109.391 146.361 126.736 1.00 166.01 ? 233 ASP A O     1 
ATOM   1522 C CB    . ASP A 1 233 ? 106.544 146.804 126.847 1.00 167.25 ? 233 ASP A CB    1 
ATOM   1523 C CG    . ASP A 1 233 ? 106.516 148.300 126.572 1.00 166.29 ? 233 ASP A CG    1 
ATOM   1524 O OD1   . ASP A 1 233 ? 107.091 149.079 127.361 1.00 167.32 ? 233 ASP A OD1   1 
ATOM   1525 O OD2   . ASP A 1 233 ? 105.911 148.699 125.555 1.00 165.22 ? 233 ASP A OD2   1 
ATOM   1526 N N     . GLY A 1 234 ? 109.532 147.501 128.670 1.00 167.03 ? 234 GLY A N     1 
ATOM   1527 C CA    . GLY A 1 234 ? 110.925 147.849 128.494 1.00 164.20 ? 234 GLY A CA    1 
ATOM   1528 C C     . GLY A 1 234 ? 111.185 149.189 127.842 1.00 164.25 ? 234 GLY A C     1 
ATOM   1529 O O     . GLY A 1 234 ? 112.350 149.600 127.758 1.00 162.10 ? 234 GLY A O     1 
ATOM   1530 N N     . THR A 1 235 ? 110.152 149.883 127.378 1.00 166.48 ? 235 THR A N     1 
ATOM   1531 C CA    . THR A 1 235 ? 110.318 151.207 126.799 1.00 165.54 ? 235 THR A CA    1 
ATOM   1532 C C     . THR A 1 235 ? 110.184 152.278 127.878 1.00 164.83 ? 235 THR A C     1 
ATOM   1533 O O     . THR A 1 235 ? 109.622 152.049 128.952 1.00 164.19 ? 235 THR A O     1 
ATOM   1534 C CB    . THR A 1 235 ? 109.297 151.450 125.687 1.00 163.96 ? 235 THR A CB    1 
ATOM   1535 O OG1   . THR A 1 235 ? 107.978 151.495 126.246 1.00 165.06 ? 235 THR A OG1   1 
ATOM   1536 C CG2   . THR A 1 235 ? 109.365 150.339 124.649 1.00 161.22 ? 235 THR A CG2   1 
ATOM   1537 N N     . LEU A 1 236 ? 110.713 153.460 127.577 1.00 162.98 ? 236 LEU A N     1 
ATOM   1538 C CA    . LEU A 1 236 ? 110.743 154.571 128.515 1.00 160.57 ? 236 LEU A CA    1 
ATOM   1539 C C     . LEU A 1 236 ? 109.982 155.761 127.945 1.00 157.59 ? 236 LEU A C     1 
ATOM   1540 O O     . LEU A 1 236 ? 109.850 155.909 126.728 1.00 156.98 ? 236 LEU A O     1 
ATOM   1541 C CB    . LEU A 1 236 ? 112.184 154.990 128.847 1.00 157.35 ? 236 LEU A CB    1 
ATOM   1542 C CG    . LEU A 1 236 ? 113.080 153.994 129.592 1.00 154.70 ? 236 LEU A CG    1 
ATOM   1543 C CD1   . LEU A 1 236 ? 112.315 153.310 130.718 1.00 156.21 ? 236 LEU A CD1   1 
ATOM   1544 C CD2   . LEU A 1 236 ? 113.705 152.969 128.649 1.00 154.06 ? 236 LEU A CD2   1 
ATOM   1545 N N     . GLU A 1 237 ? 109.475 156.605 128.840 1.00 157.54 ? 237 GLU A N     1 
ATOM   1546 C CA    . GLU A 1 237 ? 108.745 157.810 128.469 1.00 156.59 ? 237 GLU A CA    1 
ATOM   1547 C C     . GLU A 1 237 ? 109.517 159.030 128.948 1.00 154.93 ? 237 GLU A C     1 
ATOM   1548 O O     . GLU A 1 237 ? 109.978 159.066 130.094 1.00 154.73 ? 237 GLU A O     1 
ATOM   1549 C CB    . GLU A 1 237 ? 107.332 157.804 129.060 1.00 160.95 ? 237 GLU A CB    1 
ATOM   1550 C CG    . GLU A 1 237 ? 106.456 156.667 128.553 1.00 163.51 ? 237 GLU A CG    1 
ATOM   1551 C CD    . GLU A 1 237 ? 105.040 156.737 129.089 1.00 168.31 ? 237 GLU A CD    1 
ATOM   1552 O OE1   . GLU A 1 237 ? 104.748 157.654 129.886 1.00 168.60 ? 237 GLU A OE1   1 
ATOM   1553 O OE2   . GLU A 1 237 ? 104.217 155.876 128.712 1.00 168.39 ? 237 GLU A OE2   1 
ATOM   1554 N N     . ILE A 1 238 ? 109.660 160.024 128.072 1.00 153.52 ? 238 ILE A N     1 
ATOM   1555 C CA    . ILE A 1 238 ? 110.434 161.219 128.391 1.00 150.44 ? 238 ILE A CA    1 
ATOM   1556 C C     . ILE A 1 238 ? 109.565 162.464 128.277 1.00 149.37 ? 238 ILE A C     1 
ATOM   1557 O O     . ILE A 1 238 ? 110.074 163.570 128.060 1.00 151.07 ? 238 ILE A O     1 
ATOM   1558 C CB    . ILE A 1 238 ? 111.673 161.334 127.485 1.00 148.55 ? 238 ILE A CB    1 
ATOM   1559 C CG1   . ILE A 1 238 ? 111.272 161.219 126.014 1.00 144.84 ? 238 ILE A CG1   1 
ATOM   1560 C CG2   . ILE A 1 238 ? 112.702 160.279 127.858 1.00 151.67 ? 238 ILE A CG2   1 
ATOM   1561 C CD1   . ILE A 1 238 ? 112.439 161.297 125.058 1.00 142.37 ? 238 ILE A CD1   1 
ATOM   1562 N N     . GLY A 1 239 ? 108.254 162.298 128.422 1.00 148.37 ? 239 GLY A N     1 
ATOM   1563 C CA    . GLY A 1 239 ? 107.386 163.457 128.439 1.00 151.76 ? 239 GLY A CA    1 
ATOM   1564 C C     . GLY A 1 239 ? 107.184 164.098 127.073 1.00 157.33 ? 239 GLY A C     1 
ATOM   1565 O O     . GLY A 1 239 ? 107.423 163.502 126.019 1.00 159.54 ? 239 GLY A O     1 
ATOM   1566 N N     . ASP A 1 240 ? 106.741 165.355 127.117 1.00 158.13 ? 240 ASP A N     1 
ATOM   1567 C CA    . ASP A 1 240 ? 106.307 166.066 125.919 1.00 158.33 ? 240 ASP A CA    1 
ATOM   1568 C C     . ASP A 1 240 ? 107.449 166.220 124.922 1.00 157.75 ? 240 ASP A C     1 
ATOM   1569 O O     . ASP A 1 240 ? 108.481 166.824 125.231 1.00 158.28 ? 240 ASP A O     1 
ATOM   1570 C CB    . ASP A 1 240 ? 105.751 167.435 126.308 1.00 157.40 ? 240 ASP A CB    1 
ATOM   1571 C CG    . ASP A 1 240 ? 105.044 168.126 125.159 1.00 155.94 ? 240 ASP A CG    1 
ATOM   1572 O OD1   . ASP A 1 240 ? 104.809 167.470 124.123 1.00 154.09 ? 240 ASP A OD1   1 
ATOM   1573 O OD2   . ASP A 1 240 ? 104.722 169.325 125.293 1.00 156.02 ? 240 ASP A OD2   1 
ATOM   1574 N N     . THR A 1 241 ? 107.256 165.671 123.724 1.00 155.10 ? 241 THR A N     1 
ATOM   1575 C CA    . THR A 1 241 ? 108.218 165.772 122.631 1.00 153.25 ? 241 THR A CA    1 
ATOM   1576 C C     . THR A 1 241 ? 107.488 166.011 121.312 1.00 153.80 ? 241 THR A C     1 
ATOM   1577 O O     . THR A 1 241 ? 107.854 165.469 120.264 1.00 153.80 ? 241 THR A O     1 
ATOM   1578 C CB    . THR A 1 241 ? 109.102 164.523 122.573 1.00 154.17 ? 241 THR A CB    1 
ATOM   1579 O OG1   . THR A 1 241 ? 110.016 164.609 121.471 1.00 156.86 ? 241 THR A OG1   1 
ATOM   1580 C CG2   . THR A 1 241 ? 108.252 163.266 122.448 1.00 156.66 ? 241 THR A CG2   1 
ATOM   1581 N N     . THR A 1 242 ? 106.438 166.837 121.348 1.00 153.38 ? 242 THR A N     1 
ATOM   1582 C CA    . THR A 1 242 ? 105.592 167.005 120.170 1.00 150.55 ? 242 THR A CA    1 
ATOM   1583 C C     . THR A 1 242 ? 106.276 167.815 119.074 1.00 141.16 ? 242 THR A C     1 
ATOM   1584 O O     . THR A 1 242 ? 106.087 167.527 117.888 1.00 139.54 ? 242 THR A O     1 
ATOM   1585 C CB    . THR A 1 242 ? 104.263 167.659 120.561 1.00 150.56 ? 242 THR A CB    1 
ATOM   1586 O OG1   . THR A 1 242 ? 103.487 167.913 119.383 1.00 151.02 ? 242 THR A OG1   1 
ATOM   1587 C CG2   . THR A 1 242 ? 104.495 168.969 121.306 1.00 147.62 ? 242 THR A CG2   1 
ATOM   1588 N N     . ALA A 1 243 ? 107.072 168.817 119.441 1.00 137.91 ? 243 ALA A N     1 
ATOM   1589 C CA    . ALA A 1 243 ? 107.651 169.735 118.471 1.00 139.23 ? 243 ALA A CA    1 
ATOM   1590 C C     . ALA A 1 243 ? 108.959 169.241 117.869 1.00 145.65 ? 243 ALA A C     1 
ATOM   1591 O O     . ALA A 1 243 ? 109.431 169.831 116.891 1.00 149.93 ? 243 ALA A O     1 
ATOM   1592 C CB    . ALA A 1 243 ? 107.878 171.107 119.115 1.00 137.14 ? 243 ALA A CB    1 
ATOM   1593 N N     . PHE A 1 244 ? 109.554 168.187 118.417 1.00 147.66 ? 244 PHE A N     1 
ATOM   1594 C CA    . PHE A 1 244 ? 110.863 167.744 117.963 1.00 150.70 ? 244 PHE A CA    1 
ATOM   1595 C C     . PHE A 1 244 ? 110.751 166.931 116.677 1.00 153.86 ? 244 PHE A C     1 
ATOM   1596 O O     . PHE A 1 244 ? 109.732 166.291 116.404 1.00 153.49 ? 244 PHE A O     1 
ATOM   1597 C CB    . PHE A 1 244 ? 111.557 166.935 119.057 1.00 152.85 ? 244 PHE A CB    1 
ATOM   1598 C CG    . PHE A 1 244 ? 111.796 167.715 120.320 1.00 153.98 ? 244 PHE A CG    1 
ATOM   1599 C CD1   . PHE A 1 244 ? 111.927 169.095 120.281 1.00 150.64 ? 244 PHE A CD1   1 
ATOM   1600 C CD2   . PHE A 1 244 ? 111.881 167.075 121.544 1.00 157.46 ? 244 PHE A CD2   1 
ATOM   1601 C CE1   . PHE A 1 244 ? 112.143 169.819 121.437 1.00 151.56 ? 244 PHE A CE1   1 
ATOM   1602 C CE2   . PHE A 1 244 ? 112.096 167.795 122.706 1.00 157.23 ? 244 PHE A CE2   1 
ATOM   1603 C CZ    . PHE A 1 244 ? 112.228 169.169 122.651 1.00 155.70 ? 244 PHE A CZ    1 
ATOM   1604 N N     . SER A 1 245 ? 111.824 166.962 115.890 1.00 157.75 ? 245 SER A N     1 
ATOM   1605 C CA    . SER A 1 245 ? 111.823 166.421 114.536 1.00 159.47 ? 245 SER A CA    1 
ATOM   1606 C C     . SER A 1 245 ? 111.954 164.898 114.564 1.00 163.67 ? 245 SER A C     1 
ATOM   1607 O O     . SER A 1 245 ? 111.894 164.257 115.616 1.00 164.92 ? 245 SER A O     1 
ATOM   1608 C CB    . SER A 1 245 ? 112.935 167.067 113.715 1.00 157.31 ? 245 SER A CB    1 
ATOM   1609 O OG    . SER A 1 245 ? 114.206 166.797 114.279 1.00 158.42 ? 245 SER A OG    1 
ATOM   1610 N N     . CYS A 1 246 ? 112.125 164.304 113.385 1.00 165.06 ? 246 CYS A N     1 
ATOM   1611 C CA    . CYS A 1 246 ? 112.212 162.858 113.247 1.00 165.87 ? 246 CYS A CA    1 
ATOM   1612 C C     . CYS A 1 246 ? 113.591 162.346 113.650 1.00 166.97 ? 246 CYS A C     1 
ATOM   1613 O O     . CYS A 1 246 ? 114.608 163.024 113.479 1.00 162.91 ? 246 CYS A O     1 
ATOM   1614 C CB    . CYS A 1 246 ? 111.903 162.444 111.807 1.00 164.01 ? 246 CYS A CB    1 
ATOM   1615 S SG    . CYS A 1 246 ? 111.863 160.659 111.519 1.00 158.51 ? 246 CYS A SG    1 
ATOM   1616 N N     . TYR A 1 247 ? 113.612 161.130 114.193 1.00 169.95 ? 247 TYR A N     1 
ATOM   1617 C CA    . TYR A 1 247 ? 114.862 160.482 114.567 1.00 170.09 ? 247 TYR A CA    1 
ATOM   1618 C C     . TYR A 1 247 ? 115.617 160.027 113.323 1.00 170.21 ? 247 TYR A C     1 
ATOM   1619 O O     . TYR A 1 247 ? 115.028 159.448 112.404 1.00 172.11 ? 247 TYR A O     1 
ATOM   1620 C CB    . TYR A 1 247 ? 114.574 159.295 115.487 1.00 166.80 ? 247 TYR A CB    1 
ATOM   1621 C CG    . TYR A 1 247 ? 115.755 158.385 115.735 1.00 164.58 ? 247 TYR A CG    1 
ATOM   1622 C CD1   . TYR A 1 247 ? 116.714 158.703 116.687 1.00 159.95 ? 247 TYR A CD1   1 
ATOM   1623 C CD2   . TYR A 1 247 ? 115.901 157.198 115.028 1.00 165.50 ? 247 TYR A CD2   1 
ATOM   1624 C CE1   . TYR A 1 247 ? 117.791 157.870 116.919 1.00 158.41 ? 247 TYR A CE1   1 
ATOM   1625 C CE2   . TYR A 1 247 ? 116.974 156.360 115.254 1.00 164.72 ? 247 TYR A CE2   1 
ATOM   1626 C CZ    . TYR A 1 247 ? 117.915 156.700 116.201 1.00 161.02 ? 247 TYR A CZ    1 
ATOM   1627 O OH    . TYR A 1 247 ? 118.985 155.865 116.426 1.00 160.68 ? 247 TYR A OH    1 
ATOM   1628 N N     . LEU A 1 248 ? 116.925 160.292 113.290 1.00 167.63 ? 248 LEU A N     1 
ATOM   1629 C CA    . LEU A 1 248 ? 117.757 159.925 112.148 1.00 165.18 ? 248 LEU A CA    1 
ATOM   1630 C C     . LEU A 1 248 ? 118.555 158.649 112.397 1.00 165.00 ? 248 LEU A C     1 
ATOM   1631 O O     . LEU A 1 248 ? 118.379 157.657 111.683 1.00 165.28 ? 248 LEU A O     1 
ATOM   1632 C CB    . LEU A 1 248 ? 118.703 161.081 111.795 1.00 162.37 ? 248 LEU A CB    1 
ATOM   1633 C CG    . LEU A 1 248 ? 118.243 162.055 110.707 1.00 162.13 ? 248 LEU A CG    1 
ATOM   1634 C CD1   . LEU A 1 248 ? 118.094 161.335 109.375 1.00 160.25 ? 248 LEU A CD1   1 
ATOM   1635 C CD2   . LEU A 1 248 ? 116.944 162.744 111.096 1.00 159.04 ? 248 LEU A CD2   1 
ATOM   1636 N N     . ARG A 1 249 ? 119.415 158.651 113.415 1.00 164.84 ? 249 ARG A N     1 
ATOM   1637 C CA    . ARG A 1 249 ? 120.275 157.517 113.740 1.00 164.91 ? 249 ARG A CA    1 
ATOM   1638 C C     . ARG A 1 249 ? 121.065 157.871 114.994 1.00 162.39 ? 249 ARG A C     1 
ATOM   1639 O O     . ARG A 1 249 ? 121.077 159.022 115.441 1.00 162.40 ? 249 ARG A O     1 
ATOM   1640 C CB    . ARG A 1 249 ? 121.234 157.158 112.601 1.00 163.50 ? 249 ARG A CB    1 
ATOM   1641 C CG    . ARG A 1 249 ? 122.226 158.257 112.255 1.00 163.69 ? 249 ARG A CG    1 
ATOM   1642 C CD    . ARG A 1 249 ? 123.284 157.760 111.281 1.00 160.91 ? 249 ARG A CD    1 
ATOM   1643 N NE    . ARG A 1 249 ? 124.089 156.687 111.852 1.00 159.66 ? 249 ARG A NE    1 
ATOM   1644 C CZ    . ARG A 1 249 ? 125.208 156.873 112.538 1.00 156.83 ? 249 ARG A CZ    1 
ATOM   1645 N NH1   . ARG A 1 249 ? 125.690 158.085 112.759 1.00 151.17 ? 249 ARG A NH1   1 
ATOM   1646 N NH2   . ARG A 1 249 ? 125.860 155.817 113.016 1.00 156.57 ? 249 ARG A NH2   1 
ATOM   1647 N N     . GLY A 1 250 ? 121.732 156.862 115.551 1.00 160.20 ? 250 GLY A N     1 
ATOM   1648 C CA    . GLY A 1 250 ? 122.623 157.085 116.677 1.00 162.10 ? 250 GLY A CA    1 
ATOM   1649 C C     . GLY A 1 250 ? 121.890 157.601 117.897 1.00 162.26 ? 250 GLY A C     1 
ATOM   1650 O O     . GLY A 1 250 ? 120.754 157.210 118.189 1.00 160.85 ? 250 GLY A O     1 
ATOM   1651 N N     . GLY A 1 251 ? 122.551 158.495 118.627 1.00 161.43 ? 251 GLY A N     1 
ATOM   1652 C CA    . GLY A 1 251 ? 121.971 159.081 119.818 1.00 158.23 ? 251 GLY A CA    1 
ATOM   1653 C C     . GLY A 1 251 ? 122.354 158.357 121.092 1.00 155.71 ? 251 GLY A C     1 
ATOM   1654 O O     . GLY A 1 251 ? 122.338 157.124 121.143 1.00 153.38 ? 251 GLY A O     1 
ATOM   1655 N N     . ALA A 1 252 ? 122.698 159.117 122.128 1.00 157.34 ? 252 ALA A N     1 
ATOM   1656 C CA    . ALA A 1 252 ? 123.076 158.563 123.419 1.00 155.79 ? 252 ALA A CA    1 
ATOM   1657 C C     . ALA A 1 252 ? 122.327 159.294 124.522 1.00 153.71 ? 252 ALA A C     1 
ATOM   1658 O O     . ALA A 1 252 ? 122.112 160.506 124.440 1.00 152.95 ? 252 ALA A O     1 
ATOM   1659 C CB    . ALA A 1 252 ? 124.588 158.667 123.653 1.00 155.06 ? 252 ALA A CB    1 
ATOM   1660 N N     . VAL A 1 253 ? 121.930 158.552 125.553 1.00 152.07 ? 253 VAL A N     1 
ATOM   1661 C CA    . VAL A 1 253 ? 121.199 159.097 126.690 1.00 151.83 ? 253 VAL A CA    1 
ATOM   1662 C C     . VAL A 1 253 ? 121.957 158.740 127.961 1.00 149.80 ? 253 VAL A C     1 
ATOM   1663 O O     . VAL A 1 253 ? 122.386 157.593 128.136 1.00 151.32 ? 253 VAL A O     1 
ATOM   1664 C CB    . VAL A 1 253 ? 119.750 158.575 126.739 1.00 151.91 ? 253 VAL A CB    1 
ATOM   1665 C CG1   . VAL A 1 253 ? 119.715 157.054 126.640 1.00 151.87 ? 253 VAL A CG1   1 
ATOM   1666 C CG2   . VAL A 1 253 ? 119.049 159.051 128.003 1.00 148.45 ? 253 VAL A CG2   1 
ATOM   1667 N N     . THR A 1 254 ? 122.139 159.727 128.837 1.00 144.40 ? 254 THR A N     1 
ATOM   1668 C CA    . THR A 1 254 ? 122.843 159.520 130.096 1.00 140.43 ? 254 THR A CA    1 
ATOM   1669 C C     . THR A 1 254 ? 122.076 160.212 131.210 1.00 139.10 ? 254 THR A C     1 
ATOM   1670 O O     . THR A 1 254 ? 121.735 161.391 131.088 1.00 137.33 ? 254 THR A O     1 
ATOM   1671 C CB    . THR A 1 254 ? 124.276 160.062 130.026 1.00 139.98 ? 254 THR A CB    1 
ATOM   1672 O OG1   . THR A 1 254 ? 124.976 159.432 128.946 1.00 141.64 ? 254 THR A OG1   1 
ATOM   1673 C CG2   . THR A 1 254 ? 125.014 159.789 131.328 1.00 137.12 ? 254 THR A CG2   1 
ATOM   1674 N N     . GLU A 1 255 ? 121.794 159.483 132.285 1.00 137.03 ? 255 GLU A N     1 
ATOM   1675 C CA    . GLU A 1 255 ? 121.122 160.087 133.424 1.00 132.80 ? 255 GLU A CA    1 
ATOM   1676 C C     . GLU A 1 255 ? 122.098 160.951 134.211 1.00 128.45 ? 255 GLU A C     1 
ATOM   1677 O O     . GLU A 1 255 ? 123.296 160.662 134.289 1.00 130.33 ? 255 GLU A O     1 
ATOM   1678 C CB    . GLU A 1 255 ? 120.507 159.019 134.332 1.00 134.58 ? 255 GLU A CB    1 
ATOM   1679 C CG    . GLU A 1 255 ? 121.487 158.304 135.252 1.00 133.83 ? 255 GLU A CG    1 
ATOM   1680 C CD    . GLU A 1 255 ? 122.137 157.098 134.606 1.00 135.11 ? 255 GLU A CD    1 
ATOM   1681 O OE1   . GLU A 1 255 ? 121.857 156.829 133.419 1.00 134.82 ? 255 GLU A OE1   1 
ATOM   1682 O OE2   . GLU A 1 255 ? 122.924 156.414 135.291 1.00 134.61 ? 255 GLU A OE2   1 
ATOM   1683 N N     . VAL A 1 256 ? 121.577 162.031 134.784 1.00 120.57 ? 256 VAL A N     1 
ATOM   1684 C CA    . VAL A 1 256 ? 122.370 162.953 135.588 1.00 111.46 ? 256 VAL A CA    1 
ATOM   1685 C C     . VAL A 1 256 ? 122.147 162.628 137.058 1.00 107.97 ? 256 VAL A C     1 
ATOM   1686 O O     . VAL A 1 256 ? 121.003 162.477 137.505 1.00 111.00 ? 256 VAL A O     1 
ATOM   1687 C CB    . VAL A 1 256 ? 122.015 164.417 135.277 1.00 112.58 ? 256 VAL A CB    1 
ATOM   1688 C CG1   . VAL A 1 256 ? 122.582 164.819 133.926 1.00 117.40 ? 256 VAL A CG1   1 
ATOM   1689 C CG2   . VAL A 1 256 ? 120.510 164.624 135.300 1.00 120.32 ? 256 VAL A CG2   1 
ATOM   1690 N N     . LYS A 1 257 ? 123.240 162.501 137.806 1.00 96.38  ? 257 LYS A N     1 
ATOM   1691 C CA    . LYS A 1 257 ? 123.171 162.198 139.233 1.00 77.31  ? 257 LYS A CA    1 
ATOM   1692 C C     . LYS A 1 257 ? 122.789 163.472 139.973 1.00 75.08  ? 257 LYS A C     1 
ATOM   1693 O O     . LYS A 1 257 ? 123.599 164.390 140.118 1.00 81.20  ? 257 LYS A O     1 
ATOM   1694 C CB    . LYS A 1 257 ? 124.499 161.636 139.726 1.00 74.70  ? 257 LYS A CB    1 
ATOM   1695 C CG    . LYS A 1 257 ? 124.808 160.249 139.191 1.00 78.78  ? 257 LYS A CG    1 
ATOM   1696 C CD    . LYS A 1 257 ? 126.295 159.948 139.233 1.00 84.25  ? 257 LYS A CD    1 
ATOM   1697 C CE    . LYS A 1 257 ? 126.837 159.986 140.648 1.00 82.17  ? 257 LYS A CE    1 
ATOM   1698 N NZ    . LYS A 1 257 ? 128.310 159.768 140.670 1.00 86.16  ? 257 LYS A NZ    1 
ATOM   1699 N N     . ARG A 1 258 ? 121.546 163.531 140.440 1.00 76.19  ? 258 ARG A N     1 
ATOM   1700 C CA    . ARG A 1 258 ? 121.060 164.709 141.139 1.00 85.97  ? 258 ARG A CA    1 
ATOM   1701 C C     . ARG A 1 258 ? 121.709 164.831 142.516 1.00 87.89  ? 258 ARG A C     1 
ATOM   1702 O O     . ARG A 1 258 ? 122.183 163.855 143.104 1.00 89.37  ? 258 ARG A O     1 
ATOM   1703 C CB    . ARG A 1 258 ? 119.541 164.656 141.286 1.00 93.23  ? 258 ARG A CB    1 
ATOM   1704 C CG    . ARG A 1 258 ? 119.048 163.522 142.172 1.00 95.77  ? 258 ARG A CG    1 
ATOM   1705 C CD    . ARG A 1 258 ? 117.542 163.574 142.373 1.00 102.74 ? 258 ARG A CD    1 
ATOM   1706 N NE    . ARG A 1 258 ? 116.806 163.230 141.162 1.00 118.06 ? 258 ARG A NE    1 
ATOM   1707 C CZ    . ARG A 1 258 ? 116.303 164.113 140.312 1.00 123.63 ? 258 ARG A CZ    1 
ATOM   1708 N NH1   . ARG A 1 258 ? 116.440 165.415 140.505 1.00 130.79 ? 258 ARG A NH1   1 
ATOM   1709 N NH2   . ARG A 1 258 ? 115.643 163.680 139.242 1.00 119.73 ? 258 ARG A NH2   1 
ATOM   1710 N N     . ALA A 1 259 ? 121.727 166.059 143.027 1.00 84.37  ? 259 ALA A N     1 
ATOM   1711 C CA    . ALA A 1 259 ? 122.251 166.329 144.355 1.00 78.01  ? 259 ALA A CA    1 
ATOM   1712 C C     . ALA A 1 259 ? 121.167 166.124 145.410 1.00 71.49  ? 259 ALA A C     1 
ATOM   1713 O O     . ALA A 1 259 ? 119.968 166.193 145.129 1.00 72.03  ? 259 ALA A O     1 
ATOM   1714 C CB    . ALA A 1 259 ? 122.805 167.751 144.435 1.00 74.59  ? 259 ALA A CB    1 
ATOM   1715 N N     . LYS A 1 260 ? 121.608 165.878 146.642 1.00 64.32  ? 260 LYS A N     1 
ATOM   1716 C CA    . LYS A 1 260 ? 120.710 165.615 147.757 1.00 64.09  ? 260 LYS A CA    1 
ATOM   1717 C C     . LYS A 1 260 ? 121.132 166.445 148.961 1.00 62.61  ? 260 LYS A C     1 
ATOM   1718 O O     . LYS A 1 260 ? 122.301 166.812 149.105 1.00 61.51  ? 260 LYS A O     1 
ATOM   1719 C CB    . LYS A 1 260 ? 120.693 164.119 148.116 1.00 66.03  ? 260 LYS A CB    1 
ATOM   1720 C CG    . LYS A 1 260 ? 119.639 163.722 149.142 1.00 66.04  ? 260 LYS A CG    1 
ATOM   1721 C CD    . LYS A 1 260 ? 118.243 164.131 148.699 1.00 64.89  ? 260 LYS A CD    1 
ATOM   1722 C CE    . LYS A 1 260 ? 117.816 163.383 147.445 1.00 72.22  ? 260 LYS A CE    1 
ATOM   1723 N NZ    . LYS A 1 260 ? 116.448 163.772 147.005 1.00 78.10  ? 260 LYS A NZ    1 
ATOM   1724 N N     . THR A 1 261 ? 120.164 166.752 149.820 1.00 59.96  ? 261 THR A N     1 
ATOM   1725 C CA    . THR A 1 261 ? 120.393 167.557 151.012 1.00 51.91  ? 261 THR A CA    1 
ATOM   1726 C C     . THR A 1 261 ? 120.542 166.648 152.226 1.00 53.35  ? 261 THR A C     1 
ATOM   1727 O O     . THR A 1 261 ? 119.711 165.762 152.452 1.00 57.47  ? 261 THR A O     1 
ATOM   1728 C CB    . THR A 1 261 ? 119.246 168.545 151.231 1.00 52.12  ? 261 THR A CB    1 
ATOM   1729 O OG1   . THR A 1 261 ? 119.134 169.408 150.093 1.00 60.71  ? 261 THR A OG1   1 
ATOM   1730 C CG2   . THR A 1 261 ? 119.494 169.385 152.472 1.00 49.58  ? 261 THR A CG2   1 
ATOM   1731 N N     . VAL A 1 262 ? 121.600 166.873 153.000 1.00 45.44  ? 262 VAL A N     1 
ATOM   1732 C CA    . VAL A 1 262 ? 121.902 166.104 154.200 1.00 34.48  ? 262 VAL A CA    1 
ATOM   1733 C C     . VAL A 1 262 ? 121.939 167.066 155.378 1.00 35.94  ? 262 VAL A C     1 
ATOM   1734 O O     . VAL A 1 262 ? 122.613 168.102 155.318 1.00 43.70  ? 262 VAL A O     1 
ATOM   1735 C CB    . VAL A 1 262 ? 123.239 165.352 154.070 1.00 32.34  ? 262 VAL A CB    1 
ATOM   1736 C CG1   . VAL A 1 262 ? 123.439 164.426 155.252 1.00 37.32  ? 262 VAL A CG1   1 
ATOM   1737 C CG2   . VAL A 1 262 ? 123.290 164.576 152.768 1.00 41.99  ? 262 VAL A CG2   1 
ATOM   1738 N N     . SER A 1 263 ? 121.211 166.728 156.438 1.00 33.66  ? 263 SER A N     1 
ATOM   1739 C CA    . SER A 1 263 ? 121.156 167.531 157.652 1.00 34.13  ? 263 SER A CA    1 
ATOM   1740 C C     . SER A 1 263 ? 121.780 166.749 158.798 1.00 34.46  ? 263 SER A C     1 
ATOM   1741 O O     . SER A 1 263 ? 121.457 165.574 159.003 1.00 36.67  ? 263 SER A O     1 
ATOM   1742 C CB    . SER A 1 263 ? 119.714 167.915 157.997 1.00 41.31  ? 263 SER A CB    1 
ATOM   1743 O OG    . SER A 1 263 ? 119.032 166.848 158.634 1.00 46.91  ? 263 SER A OG    1 
ATOM   1744 N N     . HIS A 1 264 ? 122.675 167.399 159.536 1.00 31.70  ? 264 HIS A N     1 
ATOM   1745 C CA    . HIS A 1 264 ? 123.373 166.777 160.649 1.00 26.37  ? 264 HIS A CA    1 
ATOM   1746 C C     . HIS A 1 264 ? 123.171 167.605 161.908 1.00 30.74  ? 264 HIS A C     1 
ATOM   1747 O O     . HIS A 1 264 ? 123.242 168.836 161.871 1.00 35.34  ? 264 HIS A O     1 
ATOM   1748 C CB    . HIS A 1 264 ? 124.866 166.628 160.354 1.00 21.13  ? 264 HIS A CB    1 
ATOM   1749 C CG    . HIS A 1 264 ? 125.182 165.544 159.374 1.00 17.08  ? 264 HIS A CG    1 
ATOM   1750 N ND1   . HIS A 1 264 ? 126.469 165.241 158.991 1.00 16.95  ? 264 HIS A ND1   1 
ATOM   1751 C CD2   . HIS A 1 264 ? 124.379 164.689 158.702 1.00 19.89  ? 264 HIS A CD2   1 
ATOM   1752 C CE1   . HIS A 1 264 ? 126.446 164.247 158.123 1.00 18.44  ? 264 HIS A CE1   1 
ATOM   1753 N NE2   . HIS A 1 264 ? 125.189 163.892 157.932 1.00 19.55  ? 264 HIS A NE2   1 
ATOM   1754 N N     . GLU A 1 265 ? 122.920 166.924 163.014 1.00 28.33  ? 265 GLU A N     1 
ATOM   1755 C CA    . GLU A 1 265 ? 122.723 167.576 164.297 1.00 32.22  ? 265 GLU A CA    1 
ATOM   1756 C C     . GLU A 1 265 ? 124.062 167.815 164.987 1.00 34.82  ? 265 GLU A C     1 
ATOM   1757 O O     . GLU A 1 265 ? 125.030 167.088 164.745 1.00 36.49  ? 265 GLU A O     1 
ATOM   1758 C CB    . GLU A 1 265 ? 121.823 166.727 165.191 1.00 34.20  ? 265 GLU A CB    1 
ATOM   1759 C CG    . GLU A 1 265 ? 120.380 166.668 164.726 1.00 45.39  ? 265 GLU A CG    1 
ATOM   1760 C CD    . GLU A 1 265 ? 119.509 165.816 165.625 1.00 59.48  ? 265 GLU A CD    1 
ATOM   1761 O OE1   . GLU A 1 265 ? 120.022 165.305 166.642 1.00 57.77  ? 265 GLU A OE1   1 
ATOM   1762 O OE2   . GLU A 1 265 ? 118.311 165.656 165.313 1.00 62.69  ? 265 GLU A OE2   1 
ATOM   1763 N N     . PRO A 1 266 ? 124.149 168.829 165.844 1.00 31.33  ? 266 PRO A N     1 
ATOM   1764 C CA    . PRO A 1 266 ? 125.419 169.115 166.516 1.00 29.31  ? 266 PRO A CA    1 
ATOM   1765 C C     . PRO A 1 266 ? 125.778 168.029 167.517 1.00 32.99  ? 266 PRO A C     1 
ATOM   1766 O O     . PRO A 1 266 ? 124.938 167.239 167.952 1.00 35.34  ? 266 PRO A O     1 
ATOM   1767 C CB    . PRO A 1 266 ? 125.157 170.452 167.216 1.00 35.02  ? 266 PRO A CB    1 
ATOM   1768 C CG    . PRO A 1 266 ? 123.682 170.487 167.409 1.00 33.93  ? 266 PRO A CG    1 
ATOM   1769 C CD    . PRO A 1 266 ? 123.099 169.793 166.217 1.00 31.44  ? 266 PRO A CD    1 
ATOM   1770 N N     . LEU A 1 267 ? 127.065 167.996 167.875 1.00 32.55  ? 267 LEU A N     1 
ATOM   1771 C CA    . LEU A 1 267 ? 127.539 167.016 168.847 1.00 24.65  ? 267 LEU A CA    1 
ATOM   1772 C C     . LEU A 1 267 ? 126.885 167.215 170.207 1.00 27.71  ? 267 LEU A C     1 
ATOM   1773 O O     . LEU A 1 267 ? 126.775 166.264 170.988 1.00 30.96  ? 267 LEU A O     1 
ATOM   1774 C CB    . LEU A 1 267 ? 129.061 167.095 168.972 1.00 21.72  ? 267 LEU A CB    1 
ATOM   1775 C CG    . LEU A 1 267 ? 129.761 166.067 169.862 1.00 20.76  ? 267 LEU A CG    1 
ATOM   1776 C CD1   . LEU A 1 267 ? 129.682 164.681 169.259 1.00 18.42  ? 267 LEU A CD1   1 
ATOM   1777 C CD2   . LEU A 1 267 ? 131.206 166.462 170.107 1.00 27.98  ? 267 LEU A CD2   1 
ATOM   1778 N N     . ASP A 1 268 ? 126.442 168.439 170.503 1.00 30.09  ? 268 ASP A N     1 
ATOM   1779 C CA    . ASP A 1 268 ? 125.806 168.718 171.787 1.00 33.96  ? 268 ASP A CA    1 
ATOM   1780 C C     . ASP A 1 268 ? 124.517 167.928 171.963 1.00 35.72  ? 268 ASP A C     1 
ATOM   1781 O O     . ASP A 1 268 ? 124.129 167.617 173.095 1.00 32.82  ? 268 ASP A O     1 
ATOM   1782 C CB    . ASP A 1 268 ? 125.527 170.215 171.916 1.00 38.01  ? 268 ASP A CB    1 
ATOM   1783 C CG    . ASP A 1 268 ? 126.792 171.047 171.913 1.00 45.00  ? 268 ASP A CG    1 
ATOM   1784 O OD1   . ASP A 1 268 ? 127.552 170.976 170.925 1.00 48.89  ? 268 ASP A OD1   1 
ATOM   1785 O OD2   . ASP A 1 268 ? 127.023 171.781 172.897 1.00 43.54  ? 268 ASP A OD2   1 
ATOM   1786 N N     . THR A 1 269 ? 123.837 167.602 170.867 1.00 33.37  ? 269 THR A N     1 
ATOM   1787 C CA    . THR A 1 269 ? 122.619 166.809 170.917 1.00 26.64  ? 269 THR A CA    1 
ATOM   1788 C C     . THR A 1 269 ? 122.803 165.393 170.402 1.00 31.94  ? 269 THR A C     1 
ATOM   1789 O O     . THR A 1 269 ? 122.084 164.492 170.840 1.00 43.61  ? 269 THR A O     1 
ATOM   1790 C CB    . THR A 1 269 ? 121.506 167.494 170.115 1.00 33.86  ? 269 THR A CB    1 
ATOM   1791 O OG1   . THR A 1 269 ? 121.434 168.874 170.490 1.00 37.94  ? 269 THR A OG1   1 
ATOM   1792 C CG2   . THR A 1 269 ? 120.157 166.840 170.388 1.00 36.02  ? 269 THR A CG2   1 
ATOM   1793 N N     . ALA A 1 270 ? 123.760 165.168 169.499 1.00 26.22  ? 270 ALA A N     1 
ATOM   1794 C CA    . ALA A 1 270 ? 123.991 163.825 168.985 1.00 28.99  ? 270 ALA A CA    1 
ATOM   1795 C C     . ALA A 1 270 ? 124.431 162.858 170.074 1.00 33.73  ? 270 ALA A C     1 
ATOM   1796 O O     . ALA A 1 270 ? 124.229 161.648 169.929 1.00 34.32  ? 270 ALA A O     1 
ATOM   1797 C CB    . ALA A 1 270 ? 125.032 163.858 167.867 1.00 26.45  ? 270 ALA A CB    1 
ATOM   1798 N N     . LEU A 1 271 ? 125.028 163.362 171.158 1.00 33.37  ? 271 LEU A N     1 
ATOM   1799 C CA    . LEU A 1 271 ? 125.386 162.496 172.276 1.00 25.85  ? 271 LEU A CA    1 
ATOM   1800 C C     . LEU A 1 271 ? 124.156 161.891 172.937 1.00 24.27  ? 271 LEU A C     1 
ATOM   1801 O O     . LEU A 1 271 ? 124.241 160.811 173.533 1.00 29.55  ? 271 LEU A O     1 
ATOM   1802 C CB    . LEU A 1 271 ? 126.204 163.276 173.304 1.00 24.90  ? 271 LEU A CB    1 
ATOM   1803 C CG    . LEU A 1 271 ? 127.598 163.733 172.879 1.00 25.91  ? 271 LEU A CG    1 
ATOM   1804 C CD1   . LEU A 1 271 ? 128.185 164.665 173.922 1.00 24.63  ? 271 LEU A CD1   1 
ATOM   1805 C CD2   . LEU A 1 271 ? 128.508 162.537 172.659 1.00 26.81  ? 271 LEU A CD2   1 
ATOM   1806 N N     . LEU A 1 272 ? 123.012 162.567 172.852 1.00 20.91  ? 272 LEU A N     1 
ATOM   1807 C CA    . LEU A 1 272 ? 121.789 162.076 173.472 1.00 25.41  ? 272 LEU A CA    1 
ATOM   1808 C C     . LEU A 1 272 ? 120.932 161.259 172.517 1.00 32.24  ? 272 LEU A C     1 
ATOM   1809 O O     . LEU A 1 272 ? 120.168 160.397 172.968 1.00 41.55  ? 272 LEU A O     1 
ATOM   1810 C CB    . LEU A 1 272 ? 120.967 163.244 174.026 1.00 29.95  ? 272 LEU A CB    1 
ATOM   1811 C CG    . LEU A 1 272 ? 121.411 163.889 175.344 1.00 29.20  ? 272 LEU A CG    1 
ATOM   1812 C CD1   . LEU A 1 272 ? 122.722 164.647 175.200 1.00 27.03  ? 272 LEU A CD1   1 
ATOM   1813 C CD2   . LEU A 1 272 ? 120.318 164.807 175.872 1.00 33.64  ? 272 LEU A CD2   1 
ATOM   1814 N N     . GLN A 1 273 ? 121.030 161.513 171.214 1.00 29.50  ? 273 GLN A N     1 
ATOM   1815 C CA    . GLN A 1 273 ? 120.351 160.720 170.189 1.00 33.58  ? 273 GLN A CA    1 
ATOM   1816 C C     . GLN A 1 273 ? 121.380 160.378 169.120 1.00 29.63  ? 273 GLN A C     1 
ATOM   1817 O O     . GLN A 1 273 ? 121.525 161.097 168.121 1.00 36.21  ? 273 GLN A O     1 
ATOM   1818 C CB    . GLN A 1 273 ? 119.143 161.465 169.617 1.00 42.27  ? 273 GLN A CB    1 
ATOM   1819 C CG    . GLN A 1 273 ? 118.542 160.891 168.323 1.00 46.35  ? 273 GLN A CG    1 
ATOM   1820 C CD    . GLN A 1 273 ? 117.954 159.494 168.468 1.00 54.26  ? 273 GLN A CD    1 
ATOM   1821 O OE1   . GLN A 1 273 ? 118.027 158.872 169.526 1.00 57.09  ? 273 GLN A OE1   1 
ATOM   1822 N NE2   . GLN A 1 273 ? 117.362 158.996 167.388 1.00 56.04  ? 273 GLN A NE2   1 
ATOM   1823 N N     . PRO A 1 274 ? 122.149 159.307 169.318 1.00 21.88  ? 274 PRO A N     1 
ATOM   1824 C CA    . PRO A 1 274 ? 123.163 158.920 168.328 1.00 22.24  ? 274 PRO A CA    1 
ATOM   1825 C C     . PRO A 1 274 ? 122.526 158.198 167.150 1.00 29.26  ? 274 PRO A C     1 
ATOM   1826 O O     . PRO A 1 274 ? 121.886 157.158 167.316 1.00 38.87  ? 274 PRO A O     1 
ATOM   1827 C CB    . PRO A 1 274 ? 124.094 157.995 169.120 1.00 25.30  ? 274 PRO A CB    1 
ATOM   1828 C CG    . PRO A 1 274 ? 123.227 157.423 170.173 1.00 27.79  ? 274 PRO A CG    1 
ATOM   1829 C CD    . PRO A 1 274 ? 122.238 158.495 170.542 1.00 29.59  ? 274 PRO A CD    1 
ATOM   1830 N N     . ARG A 1 275 ? 122.699 158.758 165.955 1.00 26.42  ? 275 ARG A N     1 
ATOM   1831 C CA    . ARG A 1 275 ? 122.235 158.113 164.728 1.00 27.98  ? 275 ARG A CA    1 
ATOM   1832 C C     . ARG A 1 275 ? 123.395 157.330 164.112 1.00 26.98  ? 275 ARG A C     1 
ATOM   1833 O O     . ARG A 1 275 ? 123.945 157.669 163.063 1.00 32.07  ? 275 ARG A O     1 
ATOM   1834 C CB    . ARG A 1 275 ? 121.665 159.144 163.763 1.00 36.28  ? 275 ARG A CB    1 
ATOM   1835 C CG    . ARG A 1 275 ? 120.370 158.711 163.095 1.00 48.30  ? 275 ARG A CG    1 
ATOM   1836 C CD    . ARG A 1 275 ? 119.973 159.656 161.972 1.00 60.95  ? 275 ARG A CD    1 
ATOM   1837 N NE    . ARG A 1 275 ? 118.744 159.231 161.311 1.00 78.54  ? 275 ARG A NE    1 
ATOM   1838 C CZ    . ARG A 1 275 ? 117.552 159.770 161.525 1.00 84.69  ? 275 ARG A CZ    1 
ATOM   1839 N NH1   . ARG A 1 275 ? 117.389 160.777 162.368 1.00 88.64  ? 275 ARG A NH1   1 
ATOM   1840 N NH2   . ARG A 1 275 ? 116.496 159.289 160.874 1.00 80.73  ? 275 ARG A NH2   1 
ATOM   1841 N N     . VAL A 1 276 ? 123.764 156.261 164.806 1.00 23.10  ? 276 VAL A N     1 
ATOM   1842 C CA    . VAL A 1 276 ? 124.887 155.421 164.410 1.00 24.55  ? 276 VAL A CA    1 
ATOM   1843 C C     . VAL A 1 276 ? 124.470 154.524 163.255 1.00 26.54  ? 276 VAL A C     1 
ATOM   1844 O O     . VAL A 1 276 ? 123.375 153.949 163.257 1.00 33.43  ? 276 VAL A O     1 
ATOM   1845 C CB    . VAL A 1 276 ? 125.384 154.595 165.610 1.00 33.79  ? 276 VAL A CB    1 
ATOM   1846 C CG1   . VAL A 1 276 ? 124.209 153.951 166.332 1.00 31.95  ? 276 VAL A CG1   1 
ATOM   1847 C CG2   . VAL A 1 276 ? 126.381 153.537 165.159 1.00 33.53  ? 276 VAL A CG2   1 
ATOM   1848 N N     . VAL A 1 277 ? 125.340 154.406 162.256 1.00 28.13  ? 277 VAL A N     1 
ATOM   1849 C CA    . VAL A 1 277 ? 125.076 153.521 161.129 1.00 38.31  ? 277 VAL A CA    1 
ATOM   1850 C C     . VAL A 1 277 ? 125.501 152.107 161.514 1.00 41.70  ? 277 VAL A C     1 
ATOM   1851 O O     . VAL A 1 277 ? 126.635 151.877 161.949 1.00 39.93  ? 277 VAL A O     1 
ATOM   1852 C CB    . VAL A 1 277 ? 125.782 154.008 159.852 1.00 44.42  ? 277 VAL A CB    1 
ATOM   1853 C CG1   . VAL A 1 277 ? 125.433 155.465 159.586 1.00 43.66  ? 277 VAL A CG1   1 
ATOM   1854 C CG2   . VAL A 1 277 ? 127.287 153.836 159.927 1.00 41.19  ? 277 VAL A CG2   1 
ATOM   1855 N N     . ALA A 1 278 ? 124.567 151.167 161.412 1.00 45.94  ? 278 ALA A N     1 
ATOM   1856 C CA    . ALA A 1 278 ? 124.814 149.775 161.757 1.00 43.73  ? 278 ALA A CA    1 
ATOM   1857 C C     . ALA A 1 278 ? 123.630 148.951 161.282 1.00 48.58  ? 278 ALA A C     1 
ATOM   1858 O O     . ALA A 1 278 ? 122.565 149.489 160.968 1.00 46.41  ? 278 ALA A O     1 
ATOM   1859 C CB    . ALA A 1 278 ? 125.027 149.586 163.262 1.00 43.62  ? 278 ALA A CB    1 
ATOM   1860 N N     . GLN A 1 279 ? 123.831 147.639 161.232 1.00 57.04  ? 279 GLN A N     1 
ATOM   1861 C CA    . GLN A 1 279 ? 122.739 146.736 160.919 1.00 58.16  ? 279 GLN A CA    1 
ATOM   1862 C C     . GLN A 1 279 ? 121.766 146.670 162.094 1.00 54.30  ? 279 GLN A C     1 
ATOM   1863 O O     . GLN A 1 279 ? 122.054 147.129 163.203 1.00 53.38  ? 279 GLN A O     1 
ATOM   1864 C CB    . GLN A 1 279 ? 123.269 145.342 160.581 1.00 56.29  ? 279 GLN A CB    1 
ATOM   1865 C CG    . GLN A 1 279 ? 124.135 145.281 159.332 1.00 60.13  ? 279 GLN A CG    1 
ATOM   1866 C CD    . GLN A 1 279 ? 125.574 145.682 159.590 1.00 65.62  ? 279 GLN A CD    1 
ATOM   1867 O OE1   . GLN A 1 279 ? 126.003 145.795 160.738 1.00 62.16  ? 279 GLN A OE1   1 
ATOM   1868 N NE2   . GLN A 1 279 ? 126.329 145.897 158.519 1.00 63.87  ? 279 GLN A NE2   1 
ATOM   1869 N N     . SER A 1 280 ? 120.591 146.091 161.836 1.00 48.76  ? 280 SER A N     1 
ATOM   1870 C CA    . SER A 1 280 ? 119.582 145.972 162.883 1.00 51.17  ? 280 SER A CA    1 
ATOM   1871 C C     . SER A 1 280 ? 120.096 145.168 164.070 1.00 53.98  ? 280 SER A C     1 
ATOM   1872 O O     . SER A 1 280 ? 119.650 145.380 165.204 1.00 55.03  ? 280 SER A O     1 
ATOM   1873 C CB    . SER A 1 280 ? 118.314 145.336 162.317 1.00 59.61  ? 280 SER A CB    1 
ATOM   1874 O OG    . SER A 1 280 ? 117.331 145.170 163.323 1.00 69.66  ? 280 SER A OG    1 
ATOM   1875 N N     . ALA A 1 281 ? 121.028 144.244 163.834 1.00 52.36  ? 281 ALA A N     1 
ATOM   1876 C CA    . ALA A 1 281 ? 121.595 143.457 164.922 1.00 47.39  ? 281 ALA A CA    1 
ATOM   1877 C C     . ALA A 1 281 ? 122.620 144.238 165.733 1.00 46.90  ? 281 ALA A C     1 
ATOM   1878 O O     . ALA A 1 281 ? 122.731 144.027 166.946 1.00 55.15  ? 281 ALA A O     1 
ATOM   1879 C CB    . ALA A 1 281 ? 122.232 142.181 164.370 1.00 51.25  ? 281 ALA A CB    1 
ATOM   1880 N N     . GLN A 1 282 ? 123.371 145.134 165.097 1.00 46.94  ? 282 GLN A N     1 
ATOM   1881 C CA    . GLN A 1 282 ? 124.483 145.819 165.742 1.00 39.95  ? 282 GLN A CA    1 
ATOM   1882 C C     . GLN A 1 282 ? 124.123 147.199 166.276 1.00 35.02  ? 282 GLN A C     1 
ATOM   1883 O O     . GLN A 1 282 ? 125.008 147.901 166.772 1.00 34.34  ? 282 GLN A O     1 
ATOM   1884 C CB    . GLN A 1 282 ? 125.664 145.937 164.774 1.00 42.10  ? 282 GLN A CB    1 
ATOM   1885 C CG    . GLN A 1 282 ? 126.466 144.657 164.608 1.00 41.16  ? 282 GLN A CG    1 
ATOM   1886 C CD    . GLN A 1 282 ? 125.716 143.580 163.852 1.00 50.69  ? 282 GLN A CD    1 
ATOM   1887 O OE1   . GLN A 1 282 ? 124.923 143.871 162.958 1.00 54.74  ? 282 GLN A OE1   1 
ATOM   1888 N NE2   . GLN A 1 282 ? 125.962 142.326 164.211 1.00 50.83  ? 282 GLN A NE2   1 
ATOM   1889 N N     . LYS A 1 283 ? 122.857 147.609 166.187 1.00 36.07  ? 283 LYS A N     1 
ATOM   1890 C CA    . LYS A 1 283 ? 122.473 148.913 166.719 1.00 33.93  ? 283 LYS A CA    1 
ATOM   1891 C C     . LYS A 1 283 ? 122.652 148.972 168.231 1.00 35.96  ? 283 LYS A C     1 
ATOM   1892 O O     . LYS A 1 283 ? 123.158 149.966 168.764 1.00 38.18  ? 283 LYS A O     1 
ATOM   1893 C CB    . LYS A 1 283 ? 121.030 149.236 166.334 1.00 39.34  ? 283 LYS A CB    1 
ATOM   1894 C CG    . LYS A 1 283 ? 120.841 149.541 164.859 1.00 49.00  ? 283 LYS A CG    1 
ATOM   1895 C CD    . LYS A 1 283 ? 119.401 149.909 164.541 1.00 54.46  ? 283 LYS A CD    1 
ATOM   1896 C CE    . LYS A 1 283 ? 119.217 150.159 163.052 1.00 56.31  ? 283 LYS A CE    1 
ATOM   1897 N NZ    . LYS A 1 283 ? 120.144 151.209 162.547 1.00 52.53  ? 283 LYS A NZ    1 
ATOM   1898 N N     . VAL A 1 284 ? 122.258 147.911 168.938 1.00 35.28  ? 284 VAL A N     1 
ATOM   1899 C CA    . VAL A 1 284 ? 122.346 147.917 170.396 1.00 27.61  ? 284 VAL A CA    1 
ATOM   1900 C C     . VAL A 1 284 ? 123.799 147.860 170.853 1.00 31.13  ? 284 VAL A C     1 
ATOM   1901 O O     . VAL A 1 284 ? 124.186 148.536 171.813 1.00 39.49  ? 284 VAL A O     1 
ATOM   1902 C CB    . VAL A 1 284 ? 121.514 146.766 170.987 1.00 21.80  ? 284 VAL A CB    1 
ATOM   1903 C CG1   . VAL A 1 284 ? 121.591 146.783 172.503 1.00 30.56  ? 284 VAL A CG1   1 
ATOM   1904 C CG2   . VAL A 1 284 ? 120.074 146.874 170.531 1.00 23.90  ? 284 VAL A CG2   1 
ATOM   1905 N N     . ARG A 1 285 ? 124.627 147.053 170.185 1.00 25.97  ? 285 ARG A N     1 
ATOM   1906 C CA    . ARG A 1 285 ? 126.038 146.981 170.558 1.00 27.29  ? 285 ARG A CA    1 
ATOM   1907 C C     . ARG A 1 285 ? 126.747 148.311 170.324 1.00 30.16  ? 285 ARG A C     1 
ATOM   1908 O O     . ARG A 1 285 ? 127.532 148.764 171.170 1.00 30.39  ? 285 ARG A O     1 
ATOM   1909 C CB    . ARG A 1 285 ? 126.730 145.860 169.784 1.00 24.30  ? 285 ARG A CB    1 
ATOM   1910 C CG    . ARG A 1 285 ? 128.139 145.580 170.254 1.00 26.76  ? 285 ARG A CG    1 
ATOM   1911 C CD    . ARG A 1 285 ? 128.676 144.302 169.656 1.00 25.39  ? 285 ARG A CD    1 
ATOM   1912 N NE    . ARG A 1 285 ? 129.918 143.888 170.295 1.00 30.00  ? 285 ARG A NE    1 
ATOM   1913 C CZ    . ARG A 1 285 ? 129.984 143.144 171.390 1.00 40.38  ? 285 ARG A CZ    1 
ATOM   1914 N NH1   . ARG A 1 285 ? 128.891 142.722 172.005 1.00 49.98  ? 285 ARG A NH1   1 
ATOM   1915 N NH2   . ARG A 1 285 ? 131.175 142.814 171.879 1.00 40.90  ? 285 ARG A NH2   1 
ATOM   1916 N N     . ALA A 1 286 ? 126.481 148.956 169.186 1.00 27.03  ? 286 ALA A N     1 
ATOM   1917 C CA    . ALA A 1 286 ? 127.061 150.268 168.928 1.00 21.65  ? 286 ALA A CA    1 
ATOM   1918 C C     . ALA A 1 286 ? 126.552 151.298 169.927 1.00 21.40  ? 286 ALA A C     1 
ATOM   1919 O O     . ALA A 1 286 ? 127.298 152.186 170.352 1.00 24.61  ? 286 ALA A O     1 
ATOM   1920 C CB    . ALA A 1 286 ? 126.755 150.707 167.498 1.00 26.70  ? 286 ALA A CB    1 
ATOM   1921 N N     . ARG A 1 287 ? 125.281 151.193 170.313 1.00 20.54  ? 287 ARG A N     1 
ATOM   1922 C CA    . ARG A 1 287 ? 124.725 152.099 171.311 1.00 26.10  ? 287 ARG A CA    1 
ATOM   1923 C C     . ARG A 1 287 ? 125.418 151.925 172.658 1.00 26.42  ? 287 ARG A C     1 
ATOM   1924 O O     . ARG A 1 287 ? 125.709 152.907 173.357 1.00 28.33  ? 287 ARG A O     1 
ATOM   1925 C CB    . ARG A 1 287 ? 123.225 151.846 171.429 1.00 30.91  ? 287 ARG A CB    1 
ATOM   1926 C CG    . ARG A 1 287 ? 122.445 152.903 172.163 1.00 37.80  ? 287 ARG A CG    1 
ATOM   1927 C CD    . ARG A 1 287 ? 120.966 152.661 171.961 1.00 37.09  ? 287 ARG A CD    1 
ATOM   1928 N NE    . ARG A 1 287 ? 120.654 152.437 170.555 1.00 34.85  ? 287 ARG A NE    1 
ATOM   1929 C CZ    . ARG A 1 287 ? 119.427 152.304 170.072 1.00 41.53  ? 287 ARG A CZ    1 
ATOM   1930 N NH1   . ARG A 1 287 ? 118.364 152.367 170.857 1.00 45.31  ? 287 ARG A NH1   1 
ATOM   1931 N NH2   . ARG A 1 287 ? 119.261 152.107 168.767 1.00 47.10  ? 287 ARG A NH2   1 
ATOM   1932 N N     . CYS A 1 288 ? 125.702 150.677 173.030 1.00 21.17  ? 288 CYS A N     1 
ATOM   1933 C CA    . CYS A 1 288 ? 126.412 150.414 174.274 1.00 21.23  ? 288 CYS A CA    1 
ATOM   1934 C C     . CYS A 1 288 ? 127.851 150.909 174.215 1.00 23.95  ? 288 CYS A C     1 
ATOM   1935 O O     . CYS A 1 288 ? 128.373 151.401 175.221 1.00 26.93  ? 288 CYS A O     1 
ATOM   1936 C CB    . CYS A 1 288 ? 126.361 148.924 174.598 1.00 25.16  ? 288 CYS A CB    1 
ATOM   1937 S SG    . CYS A 1 288 ? 124.694 148.314 174.945 1.00 36.94  ? 288 CYS A SG    1 
ATOM   1938 N N     . LEU A 1 289 ? 128.500 150.821 173.051 1.00 22.52  ? 289 LEU A N     1 
ATOM   1939 C CA    . LEU A 1 289 ? 129.835 151.406 172.915 1.00 18.59  ? 289 LEU A CA    1 
ATOM   1940 C C     . LEU A 1 289 ? 129.787 152.931 173.008 1.00 18.50  ? 289 LEU A C     1 
ATOM   1941 O O     . LEU A 1 289 ? 130.697 153.557 173.563 1.00 22.85  ? 289 LEU A O     1 
ATOM   1942 C CB    . LEU A 1 289 ? 130.477 150.966 171.602 1.00 16.53  ? 289 LEU A CB    1 
ATOM   1943 C CG    . LEU A 1 289 ? 130.785 149.478 171.438 1.00 18.69  ? 289 LEU A CG    1 
ATOM   1944 C CD1   . LEU A 1 289 ? 131.421 149.202 170.087 1.00 20.57  ? 289 LEU A CD1   1 
ATOM   1945 C CD2   . LEU A 1 289 ? 131.683 148.996 172.551 1.00 24.07  ? 289 LEU A CD2   1 
ATOM   1946 N N     . HIS A 1 290 ? 128.736 153.541 172.458 1.00 17.66  ? 290 HIS A N     1 
ATOM   1947 C CA    . HIS A 1 290 ? 128.531 154.982 172.594 1.00 19.98  ? 290 HIS A CA    1 
ATOM   1948 C C     . HIS A 1 290 ? 128.435 155.385 174.061 1.00 24.32  ? 290 HIS A C     1 
ATOM   1949 O O     . HIS A 1 290 ? 129.127 156.307 174.519 1.00 27.21  ? 290 HIS A O     1 
ATOM   1950 C CB    . HIS A 1 290 ? 127.265 155.378 171.829 1.00 21.75  ? 290 HIS A CB    1 
ATOM   1951 C CG    . HIS A 1 290 ? 126.895 156.823 171.947 1.00 22.56  ? 290 HIS A CG    1 
ATOM   1952 N ND1   . HIS A 1 290 ? 127.511 157.815 171.219 1.00 19.29  ? 290 HIS A ND1   1 
ATOM   1953 C CD2   . HIS A 1 290 ? 125.947 157.439 172.691 1.00 25.67  ? 290 HIS A CD2   1 
ATOM   1954 C CE1   . HIS A 1 290 ? 126.969 158.982 171.519 1.00 21.04  ? 290 HIS A CE1   1 
ATOM   1955 N NE2   . HIS A 1 290 ? 126.016 158.781 172.409 1.00 24.25  ? 290 HIS A NE2   1 
ATOM   1956 N N     . GLN A 1 291 ? 127.577 154.693 174.814 1.00 22.77  ? 291 GLN A N     1 
ATOM   1957 C CA    . GLN A 1 291 ? 127.458 154.970 176.241 1.00 19.16  ? 291 GLN A CA    1 
ATOM   1958 C C     . GLN A 1 291 ? 128.763 154.696 176.980 1.00 23.96  ? 291 GLN A C     1 
ATOM   1959 O O     . GLN A 1 291 ? 129.091 155.405 177.939 1.00 29.80  ? 291 GLN A O     1 
ATOM   1960 C CB    . GLN A 1 291 ? 126.316 154.154 176.838 1.00 15.38  ? 291 GLN A CB    1 
ATOM   1961 C CG    . GLN A 1 291 ? 124.958 154.532 176.290 1.00 20.39  ? 291 GLN A CG    1 
ATOM   1962 C CD    . GLN A 1 291 ? 123.827 154.045 177.165 1.00 32.29  ? 291 GLN A CD    1 
ATOM   1963 O OE1   . GLN A 1 291 ? 123.734 154.410 178.333 1.00 37.58  ? 291 GLN A OE1   1 
ATOM   1964 N NE2   . GLN A 1 291 ? 122.962 153.208 176.607 1.00 43.60  ? 291 GLN A NE2   1 
ATOM   1965 N N     . SER A 1 292 ? 129.526 153.691 176.544 1.00 19.25  ? 292 SER A N     1 
ATOM   1966 C CA    . SER A 1 292 ? 130.825 153.426 177.153 1.00 20.37  ? 292 SER A CA    1 
ATOM   1967 C C     . SER A 1 292 ? 131.795 154.582 176.936 1.00 24.86  ? 292 SER A C     1 
ATOM   1968 O O     . SER A 1 292 ? 132.548 154.947 177.844 1.00 28.75  ? 292 SER A O     1 
ATOM   1969 C CB    . SER A 1 292 ? 131.410 152.132 176.596 1.00 19.37  ? 292 SER A CB    1 
ATOM   1970 O OG    . SER A 1 292 ? 132.644 151.842 177.226 1.00 33.83  ? 292 SER A OG    1 
ATOM   1971 N N     . PHE A 1 293 ? 131.805 155.159 175.733 1.00 23.87  ? 293 PHE A N     1 
ATOM   1972 C CA    . PHE A 1 293 ? 132.651 156.324 175.475 1.00 21.20  ? 293 PHE A CA    1 
ATOM   1973 C C     . PHE A 1 293 ? 132.222 157.516 176.324 1.00 22.19  ? 293 PHE A C     1 
ATOM   1974 O O     . PHE A 1 293 ? 133.064 158.251 176.856 1.00 28.62  ? 293 PHE A O     1 
ATOM   1975 C CB    . PHE A 1 293 ? 132.615 156.685 173.992 1.00 20.16  ? 293 PHE A CB    1 
ATOM   1976 C CG    . PHE A 1 293 ? 133.772 156.151 173.202 1.00 19.15  ? 293 PHE A CG    1 
ATOM   1977 C CD1   . PHE A 1 293 ? 133.866 154.807 172.910 1.00 17.92  ? 293 PHE A CD1   1 
ATOM   1978 C CD2   . PHE A 1 293 ? 134.752 157.003 172.727 1.00 21.87  ? 293 PHE A CD2   1 
ATOM   1979 C CE1   . PHE A 1 293 ? 134.918 154.323 172.178 1.00 17.75  ? 293 PHE A CE1   1 
ATOM   1980 C CE2   . PHE A 1 293 ? 135.804 156.519 171.992 1.00 19.75  ? 293 PHE A CE2   1 
ATOM   1981 C CZ    . PHE A 1 293 ? 135.883 155.177 171.715 1.00 17.30  ? 293 PHE A CZ    1 
ATOM   1982 N N     . ARG A 1 294 ? 130.910 157.735 176.448 1.00 20.83  ? 294 ARG A N     1 
ATOM   1983 C CA    . ARG A 1 294 ? 130.429 158.809 177.317 1.00 25.37  ? 294 ARG A CA    1 
ATOM   1984 C C     . ARG A 1 294 ? 130.870 158.590 178.765 1.00 32.08  ? 294 ARG A C     1 
ATOM   1985 O O     . ARG A 1 294 ? 131.277 159.537 179.453 1.00 36.17  ? 294 ARG A O     1 
ATOM   1986 C CB    . ARG A 1 294 ? 128.907 158.929 177.219 1.00 24.38  ? 294 ARG A CB    1 
ATOM   1987 C CG    . ARG A 1 294 ? 128.409 159.053 175.790 1.00 24.34  ? 294 ARG A CG    1 
ATOM   1988 C CD    . ARG A 1 294 ? 127.301 160.084 175.619 1.00 25.13  ? 294 ARG A CD    1 
ATOM   1989 N NE    . ARG A 1 294 ? 126.039 159.673 176.220 1.00 18.64  ? 294 ARG A NE    1 
ATOM   1990 C CZ    . ARG A 1 294 ? 125.425 160.338 177.188 1.00 21.32  ? 294 ARG A CZ    1 
ATOM   1991 N NH1   . ARG A 1 294 ? 125.929 161.454 177.686 1.00 29.43  ? 294 ARG A NH1   1 
ATOM   1992 N NH2   . ARG A 1 294 ? 124.273 159.876 177.663 1.00 21.71  ? 294 ARG A NH2   1 
ATOM   1993 N N     . ALA A 1 295 ? 130.810 157.343 179.240 1.00 25.01  ? 295 ALA A N     1 
ATOM   1994 C CA    . ALA A 1 295 ? 131.270 157.033 180.591 1.00 26.59  ? 295 ALA A CA    1 
ATOM   1995 C C     . ALA A 1 295 ? 132.773 157.243 180.738 1.00 29.68  ? 295 ALA A C     1 
ATOM   1996 O O     . ALA A 1 295 ? 133.239 157.702 181.785 1.00 32.90  ? 295 ALA A O     1 
ATOM   1997 C CB    . ALA A 1 295 ? 130.898 155.601 180.957 1.00 27.57  ? 295 ALA A CB    1 
ATOM   1998 N N     . LEU A 1 296 ? 133.551 156.892 179.712 1.00 27.28  ? 296 LEU A N     1 
ATOM   1999 C CA    . LEU A 1 296 ? 134.989 157.143 179.763 1.00 26.77  ? 296 LEU A CA    1 
ATOM   2000 C C     . LEU A 1 296 ? 135.290 158.634 179.832 1.00 29.76  ? 296 LEU A C     1 
ATOM   2001 O O     . LEU A 1 296 ? 136.207 159.056 180.546 1.00 33.09  ? 296 LEU A O     1 
ATOM   2002 C CB    . LEU A 1 296 ? 135.683 156.511 178.554 1.00 23.51  ? 296 LEU A CB    1 
ATOM   2003 C CG    . LEU A 1 296 ? 136.041 155.027 178.672 1.00 26.79  ? 296 LEU A CG    1 
ATOM   2004 C CD1   . LEU A 1 296 ? 136.442 154.436 177.330 1.00 28.16  ? 296 LEU A CD1   1 
ATOM   2005 C CD2   . LEU A 1 296 ? 137.155 154.846 179.684 1.00 30.88  ? 296 LEU A CD2   1 
ATOM   2006 N N     . HIS A 1 297 ? 134.524 159.447 179.104 1.00 28.14  ? 297 HIS A N     1 
ATOM   2007 C CA    . HIS A 1 297 ? 134.709 160.892 179.182 1.00 28.39  ? 297 HIS A CA    1 
ATOM   2008 C C     . HIS A 1 297 ? 134.334 161.428 180.560 1.00 33.44  ? 297 HIS A C     1 
ATOM   2009 O O     . HIS A 1 297 ? 135.006 162.323 181.090 1.00 36.30  ? 297 HIS A O     1 
ATOM   2010 C CB    . HIS A 1 297 ? 133.902 161.573 178.084 1.00 28.58  ? 297 HIS A CB    1 
ATOM   2011 C CG    . HIS A 1 297 ? 134.556 161.516 176.741 1.00 34.29  ? 297 HIS A CG    1 
ATOM   2012 N ND1   . HIS A 1 297 ? 133.914 161.043 175.618 1.00 36.59  ? 297 HIS A ND1   1 
ATOM   2013 C CD2   . HIS A 1 297 ? 135.796 161.881 176.338 1.00 33.33  ? 297 HIS A CD2   1 
ATOM   2014 C CE1   . HIS A 1 297 ? 134.732 161.114 174.583 1.00 32.94  ? 297 HIS A CE1   1 
ATOM   2015 N NE2   . HIS A 1 297 ? 135.881 161.618 174.993 1.00 32.95  ? 297 HIS A NE2   1 
ATOM   2016 N N     . LYS A 1 298 ? 133.264 160.895 181.155 1.00 33.70  ? 298 LYS A N     1 
ATOM   2017 C CA    . LYS A 1 298 ? 132.947 161.254 182.535 1.00 31.09  ? 298 LYS A CA    1 
ATOM   2018 C C     . LYS A 1 298 ? 134.077 160.864 183.478 1.00 28.70  ? 298 LYS A C     1 
ATOM   2019 O O     . LYS A 1 298 ? 134.403 161.610 184.409 1.00 35.73  ? 298 LYS A O     1 
ATOM   2020 C CB    . LYS A 1 298 ? 131.640 160.598 182.973 1.00 30.90  ? 298 LYS A CB    1 
ATOM   2021 C CG    . LYS A 1 298 ? 130.394 161.340 182.545 1.00 32.13  ? 298 LYS A CG    1 
ATOM   2022 C CD    . LYS A 1 298 ? 129.190 160.823 183.309 1.00 40.46  ? 298 LYS A CD    1 
ATOM   2023 C CE    . LYS A 1 298 ? 127.943 161.637 183.015 1.00 48.61  ? 298 LYS A CE    1 
ATOM   2024 N NZ    . LYS A 1 298 ? 126.798 161.205 183.862 1.00 50.90  ? 298 LYS A NZ    1 
ATOM   2025 N N     . PHE A 1 299 ? 134.675 159.691 183.264 1.00 25.56  ? 299 PHE A N     1 
ATOM   2026 C CA    . PHE A 1 299 ? 135.801 159.265 184.088 1.00 30.09  ? 299 PHE A CA    1 
ATOM   2027 C C     . PHE A 1 299 ? 136.960 160.241 183.964 1.00 35.39  ? 299 PHE A C     1 
ATOM   2028 O O     . PHE A 1 299 ? 137.604 160.592 184.959 1.00 41.34  ? 299 PHE A O     1 
ATOM   2029 C CB    . PHE A 1 299 ? 136.245 157.856 183.689 1.00 34.29  ? 299 PHE A CB    1 
ATOM   2030 C CG    . PHE A 1 299 ? 137.336 157.294 184.556 1.00 33.47  ? 299 PHE A CG    1 
ATOM   2031 C CD1   . PHE A 1 299 ? 138.669 157.566 184.295 1.00 34.01  ? 299 PHE A CD1   1 
ATOM   2032 C CD2   . PHE A 1 299 ? 137.026 156.484 185.632 1.00 35.66  ? 299 PHE A CD2   1 
ATOM   2033 C CE1   . PHE A 1 299 ? 139.665 157.051 185.099 1.00 37.45  ? 299 PHE A CE1   1 
ATOM   2034 C CE2   . PHE A 1 299 ? 138.015 155.964 186.432 1.00 41.85  ? 299 PHE A CE2   1 
ATOM   2035 C CZ    . PHE A 1 299 ? 139.336 156.249 186.167 1.00 41.38  ? 299 PHE A CZ    1 
ATOM   2036 N N     . GLN A 1 300 ? 137.254 160.669 182.736 1.00 37.03  ? 300 GLN A N     1 
ATOM   2037 C CA    . GLN A 1 300 ? 138.320 161.642 182.518 1.00 33.44  ? 300 GLN A CA    1 
ATOM   2038 C C     . GLN A 1 300 ? 138.024 162.955 183.231 1.00 32.41  ? 300 GLN A C     1 
ATOM   2039 O O     . GLN A 1 300 ? 138.919 163.557 183.834 1.00 34.10  ? 300 GLN A O     1 
ATOM   2040 C CB    . GLN A 1 300 ? 138.513 161.877 181.021 1.00 35.83  ? 300 GLN A CB    1 
ATOM   2041 C CG    . GLN A 1 300 ? 139.590 162.896 180.691 1.00 45.11  ? 300 GLN A CG    1 
ATOM   2042 C CD    . GLN A 1 300 ? 140.988 162.400 181.000 1.00 49.41  ? 300 GLN A CD    1 
ATOM   2043 O OE1   . GLN A 1 300 ? 141.271 161.208 180.908 1.00 50.70  ? 300 GLN A OE1   1 
ATOM   2044 N NE2   . GLN A 1 300 ? 141.873 163.318 181.366 1.00 50.32  ? 300 GLN A NE2   1 
ATOM   2045 N N     . GLN A 1 301 ? 136.773 163.416 183.174 1.00 34.84  ? 301 GLN A N     1 
ATOM   2046 C CA    . GLN A 1 301 ? 136.415 164.648 183.872 1.00 35.52  ? 301 GLN A CA    1 
ATOM   2047 C C     . GLN A 1 301 ? 136.558 164.500 185.384 1.00 38.37  ? 301 GLN A C     1 
ATOM   2048 O O     . GLN A 1 301 ? 137.046 165.414 186.059 1.00 46.46  ? 301 GLN A O     1 
ATOM   2049 C CB    . GLN A 1 301 ? 134.989 165.062 183.517 1.00 36.91  ? 301 GLN A CB    1 
ATOM   2050 C CG    . GLN A 1 301 ? 134.804 165.513 182.079 1.00 49.09  ? 301 GLN A CG    1 
ATOM   2051 C CD    . GLN A 1 301 ? 133.417 166.070 181.830 1.00 56.45  ? 301 GLN A CD    1 
ATOM   2052 O OE1   . GLN A 1 301 ? 132.603 166.159 182.747 1.00 57.33  ? 301 GLN A OE1   1 
ATOM   2053 N NE2   . GLN A 1 301 ? 133.141 166.449 180.588 1.00 52.13  ? 301 GLN A NE2   1 
ATOM   2054 N N     . LEU A 1 302 ? 136.133 163.361 185.933 1.00 32.27  ? 302 LEU A N     1 
ATOM   2055 C CA    . LEU A 1 302 ? 136.060 163.213 187.383 1.00 30.63  ? 302 LEU A CA    1 
ATOM   2056 C C     . LEU A 1 302 ? 137.393 162.818 188.012 1.00 33.94  ? 302 LEU A C     1 
ATOM   2057 O O     . LEU A 1 302 ? 137.611 163.089 189.198 1.00 39.63  ? 302 LEU A O     1 
ATOM   2058 C CB    . LEU A 1 302 ? 134.981 162.194 187.752 1.00 30.59  ? 302 LEU A CB    1 
ATOM   2059 C CG    . LEU A 1 302 ? 133.591 162.760 188.059 1.00 35.84  ? 302 LEU A CG    1 
ATOM   2060 C CD1   . LEU A 1 302 ? 133.040 163.555 186.884 1.00 37.13  ? 302 LEU A CD1   1 
ATOM   2061 C CD2   . LEU A 1 302 ? 132.629 161.647 188.450 1.00 39.27  ? 302 LEU A CD2   1 
ATOM   2062 N N     . HIS A 1 303 ? 138.293 162.188 187.257 1.00 33.98  ? 303 HIS A N     1 
ATOM   2063 C CA    . HIS A 1 303 ? 139.564 161.737 187.807 1.00 31.15  ? 303 HIS A CA    1 
ATOM   2064 C C     . HIS A 1 303 ? 140.780 162.429 187.211 1.00 32.01  ? 303 HIS A C     1 
ATOM   2065 O O     . HIS A 1 303 ? 141.858 162.367 187.811 1.00 35.39  ? 303 HIS A O     1 
ATOM   2066 C CB    . HIS A 1 303 ? 139.715 160.222 187.626 1.00 31.74  ? 303 HIS A CB    1 
ATOM   2067 C CG    . HIS A 1 303 ? 138.830 159.415 188.520 1.00 34.98  ? 303 HIS A CG    1 
ATOM   2068 N ND1   . HIS A 1 303 ? 137.456 159.445 188.436 1.00 33.71  ? 303 HIS A ND1   1 
ATOM   2069 C CD2   . HIS A 1 303 ? 139.126 158.545 189.514 1.00 38.77  ? 303 HIS A CD2   1 
ATOM   2070 C CE1   . HIS A 1 303 ? 136.944 158.632 189.342 1.00 38.66  ? 303 HIS A CE1   1 
ATOM   2071 N NE2   . HIS A 1 303 ? 137.936 158.073 190.010 1.00 39.80  ? 303 HIS A NE2   1 
ATOM   2072 N N     . GLY A 1 304 ? 140.649 163.071 186.054 1.00 35.91  ? 304 GLY A N     1 
ATOM   2073 C CA    . GLY A 1 304 ? 141.768 163.785 185.471 1.00 38.88  ? 304 GLY A CA    1 
ATOM   2074 C C     . GLY A 1 304 ? 142.817 162.925 184.805 1.00 40.08  ? 304 GLY A C     1 
ATOM   2075 O O     . GLY A 1 304 ? 143.841 163.456 184.367 1.00 40.94  ? 304 GLY A O     1 
ATOM   2076 N N     . ARG A 1 305 ? 142.599 161.621 184.714 1.00 37.23  ? 305 ARG A N     1 
ATOM   2077 C CA    . ARG A 1 305 ? 143.512 160.698 184.061 1.00 36.83  ? 305 ARG A CA    1 
ATOM   2078 C C     . ARG A 1 305 ? 142.704 159.586 183.413 1.00 40.08  ? 305 ARG A C     1 
ATOM   2079 O O     . ARG A 1 305 ? 141.575 159.307 183.832 1.00 42.79  ? 305 ARG A O     1 
ATOM   2080 C CB    . ARG A 1 305 ? 144.509 160.097 185.060 1.00 32.88  ? 305 ARG A CB    1 
ATOM   2081 C CG    . ARG A 1 305 ? 143.842 159.299 186.155 1.00 34.82  ? 305 ARG A CG    1 
ATOM   2082 C CD    . ARG A 1 305 ? 144.845 158.492 186.944 1.00 36.09  ? 305 ARG A CD    1 
ATOM   2083 N NE    . ARG A 1 305 ? 144.202 157.707 187.989 1.00 42.00  ? 305 ARG A NE    1 
ATOM   2084 C CZ    . ARG A 1 305 ? 143.663 156.510 187.799 1.00 44.79  ? 305 ARG A CZ    1 
ATOM   2085 N NH1   . ARG A 1 305 ? 143.658 155.935 186.609 1.00 43.50  ? 305 ARG A NH1   1 
ATOM   2086 N NH2   . ARG A 1 305 ? 143.114 155.875 188.831 1.00 42.39  ? 305 ARG A NH2   1 
ATOM   2087 N N     . PRO A 1 306 ? 143.254 158.929 182.396 1.00 35.13  ? 306 PRO A N     1 
ATOM   2088 C CA    . PRO A 1 306 ? 142.576 157.769 181.815 1.00 33.13  ? 306 PRO A CA    1 
ATOM   2089 C C     . PRO A 1 306 ? 142.625 156.586 182.764 1.00 36.61  ? 306 PRO A C     1 
ATOM   2090 O O     . PRO A 1 306 ? 143.467 156.544 183.675 1.00 42.02  ? 306 PRO A O     1 
ATOM   2091 C CB    . PRO A 1 306 ? 143.382 157.494 180.536 1.00 40.02  ? 306 PRO A CB    1 
ATOM   2092 C CG    . PRO A 1 306 ? 144.735 158.048 180.824 1.00 40.07  ? 306 PRO A CG    1 
ATOM   2093 C CD    . PRO A 1 306 ? 144.500 159.258 181.679 1.00 36.95  ? 306 PRO A CD    1 
ATOM   2094 N N     . PRO A 1 307 ? 141.727 155.618 182.600 1.00 33.90  ? 307 PRO A N     1 
ATOM   2095 C CA    . PRO A 1 307 ? 141.774 154.414 183.436 1.00 31.64  ? 307 PRO A CA    1 
ATOM   2096 C C     . PRO A 1 307 ? 143.109 153.693 183.315 1.00 33.80  ? 307 PRO A C     1 
ATOM   2097 O O     . PRO A 1 307 ? 143.687 153.588 182.231 1.00 38.34  ? 307 PRO A O     1 
ATOM   2098 C CB    . PRO A 1 307 ? 140.621 153.566 182.893 1.00 29.91  ? 307 PRO A CB    1 
ATOM   2099 C CG    . PRO A 1 307 ? 139.693 154.550 182.283 1.00 28.55  ? 307 PRO A CG    1 
ATOM   2100 C CD    . PRO A 1 307 ? 140.556 155.624 181.708 1.00 33.60  ? 307 PRO A CD    1 
ATOM   2101 N N     . LYS A 1 308 ? 143.601 153.208 184.447 1.00 33.44  ? 308 LYS A N     1 
ATOM   2102 C CA    . LYS A 1 308 ? 144.814 152.410 184.453 1.00 38.41  ? 308 LYS A CA    1 
ATOM   2103 C C     . LYS A 1 308 ? 144.598 151.152 183.616 1.00 41.78  ? 308 LYS A C     1 
ATOM   2104 O O     . LYS A 1 308 ? 143.516 150.555 183.668 1.00 41.78  ? 308 LYS A O     1 
ATOM   2105 C CB    . LYS A 1 308 ? 145.191 152.045 185.891 1.00 44.84  ? 308 LYS A CB    1 
ATOM   2106 C CG    . LYS A 1 308 ? 146.322 151.038 186.035 1.00 51.13  ? 308 LYS A CG    1 
ATOM   2107 C CD    . LYS A 1 308 ? 146.564 150.689 187.500 1.00 59.35  ? 308 LYS A CD    1 
ATOM   2108 C CE    . LYS A 1 308 ? 147.657 149.638 187.664 1.00 68.04  ? 308 LYS A CE    1 
ATOM   2109 N NZ    . LYS A 1 308 ? 147.880 149.263 189.092 1.00 61.56  ? 308 LYS A NZ    1 
ATOM   2110 N N     . PRO A 1 309 ? 145.589 150.736 182.813 1.00 36.91  ? 309 PRO A N     1 
ATOM   2111 C CA    . PRO A 1 309 ? 145.399 149.564 181.947 1.00 33.29  ? 309 PRO A CA    1 
ATOM   2112 C C     . PRO A 1 309 ? 144.933 148.324 182.694 1.00 41.73  ? 309 PRO A C     1 
ATOM   2113 O O     . PRO A 1 309 ? 145.635 147.811 183.572 1.00 49.12  ? 309 PRO A O     1 
ATOM   2114 C CB    . PRO A 1 309 ? 146.790 149.357 181.337 1.00 30.04  ? 309 PRO A CB    1 
ATOM   2115 C CG    . PRO A 1 309 ? 147.405 150.690 181.366 1.00 25.97  ? 309 PRO A CG    1 
ATOM   2116 C CD    . PRO A 1 309 ? 146.909 151.356 182.608 1.00 31.32  ? 309 PRO A CD    1 
ATOM   2117 N N     . TRP A 1 310 ? 143.737 147.848 182.345 1.00 34.03  ? 310 TRP A N     1 
ATOM   2118 C CA    . TRP A 1 310 ? 143.172 146.616 182.899 1.00 33.64  ? 310 TRP A CA    1 
ATOM   2119 C C     . TRP A 1 310 ? 143.008 146.694 184.415 1.00 39.54  ? 310 TRP A C     1 
ATOM   2120 O O     . TRP A 1 310 ? 143.158 145.698 185.123 1.00 45.67  ? 310 TRP A O     1 
ATOM   2121 C CB    . TRP A 1 310 ? 144.009 145.400 182.501 1.00 35.58  ? 310 TRP A CB    1 
ATOM   2122 C CG    . TRP A 1 310 ? 143.828 145.019 181.071 1.00 28.80  ? 310 TRP A CG    1 
ATOM   2123 C CD1   . TRP A 1 310 ? 144.601 145.395 180.022 1.00 29.34  ? 310 TRP A CD1   1 
ATOM   2124 C CD2   . TRP A 1 310 ? 142.787 144.199 180.530 1.00 25.41  ? 310 TRP A CD2   1 
ATOM   2125 N NE1   . TRP A 1 310 ? 144.115 144.856 178.857 1.00 27.18  ? 310 TRP A NE1   1 
ATOM   2126 C CE2   . TRP A 1 310 ? 142.999 144.117 179.144 1.00 25.41  ? 310 TRP A CE2   1 
ATOM   2127 C CE3   . TRP A 1 310 ? 141.699 143.522 181.086 1.00 28.95  ? 310 TRP A CE3   1 
ATOM   2128 C CZ2   . TRP A 1 310 ? 142.166 143.389 178.306 1.00 30.26  ? 310 TRP A CZ2   1 
ATOM   2129 C CZ3   . TRP A 1 310 ? 140.873 142.805 180.253 1.00 28.44  ? 310 TRP A CZ3   1 
ATOM   2130 C CH2   . TRP A 1 310 ? 141.110 142.741 178.879 1.00 29.43  ? 310 TRP A CH2   1 
ATOM   2131 N N     . ASP A 1 311 ? 142.679 147.881 184.916 1.00 40.56  ? 311 ASP A N     1 
ATOM   2132 C CA    . ASP A 1 311 ? 142.448 148.067 186.342 1.00 40.36  ? 311 ASP A CA    1 
ATOM   2133 C C     . ASP A 1 311 ? 140.988 147.780 186.661 1.00 42.58  ? 311 ASP A C     1 
ATOM   2134 O O     . ASP A 1 311 ? 140.107 148.486 186.152 1.00 49.19  ? 311 ASP A O     1 
ATOM   2135 C CB    . ASP A 1 311 ? 142.805 149.480 186.762 1.00 41.77  ? 311 ASP A CB    1 
ATOM   2136 C CG    . ASP A 1 311 ? 142.761 149.673 188.265 1.00 54.18  ? 311 ASP A CG    1 
ATOM   2137 O OD1   . ASP A 1 311 ? 142.692 148.665 189.000 1.00 51.88  ? 311 ASP A OD1   1 
ATOM   2138 O OD2   . ASP A 1 311 ? 142.795 150.838 188.711 1.00 60.77  ? 311 ASP A OD2   1 
ATOM   2139 N N     . PRO A 1 312 ? 140.684 146.765 187.472 1.00 38.81  ? 312 PRO A N     1 
ATOM   2140 C CA    . PRO A 1 312 ? 139.276 146.479 187.792 1.00 41.10  ? 312 PRO A CA    1 
ATOM   2141 C C     . PRO A 1 312 ? 138.558 147.619 188.492 1.00 46.68  ? 312 PRO A C     1 
ATOM   2142 O O     . PRO A 1 312 ? 137.354 147.798 188.277 1.00 51.10  ? 312 PRO A O     1 
ATOM   2143 C CB    . PRO A 1 312 ? 139.366 145.232 188.684 1.00 46.12  ? 312 PRO A CB    1 
ATOM   2144 C CG    . PRO A 1 312 ? 140.781 145.203 189.177 1.00 47.19  ? 312 PRO A CG    1 
ATOM   2145 C CD    . PRO A 1 312 ? 141.601 145.786 188.075 1.00 37.01  ? 312 PRO A CD    1 
ATOM   2146 N N     . VAL A 1 313 ? 139.256 148.398 189.322 1.00 46.35  ? 313 VAL A N     1 
ATOM   2147 C CA    . VAL A 1 313 ? 138.606 149.490 190.043 1.00 46.00  ? 313 VAL A CA    1 
ATOM   2148 C C     . VAL A 1 313 ? 138.152 150.574 189.073 1.00 52.54  ? 313 VAL A C     1 
ATOM   2149 O O     . VAL A 1 313 ? 137.015 151.062 189.141 1.00 57.56  ? 313 VAL A O     1 
ATOM   2150 C CB    . VAL A 1 313 ? 139.551 150.055 191.117 1.00 46.35  ? 313 VAL A CB    1 
ATOM   2151 C CG1   . VAL A 1 313 ? 138.831 151.093 191.969 1.00 53.08  ? 313 VAL A CG1   1 
ATOM   2152 C CG2   . VAL A 1 313 ? 140.104 148.932 191.976 1.00 51.10  ? 313 VAL A CG2   1 
ATOM   2153 N N     . ASP A 1 314 ? 139.037 150.965 188.155 1.00 46.67  ? 314 ASP A N     1 
ATOM   2154 C CA    . ASP A 1 314 ? 138.687 151.982 187.171 1.00 41.59  ? 314 ASP A CA    1 
ATOM   2155 C C     . ASP A 1 314 ? 137.608 151.482 186.221 1.00 41.15  ? 314 ASP A C     1 
ATOM   2156 O O     . ASP A 1 314 ? 136.710 152.242 185.840 1.00 45.45  ? 314 ASP A O     1 
ATOM   2157 C CB    . ASP A 1 314 ? 139.934 152.414 186.410 1.00 39.84  ? 314 ASP A CB    1 
ATOM   2158 C CG    . ASP A 1 314 ? 140.934 153.110 187.300 1.00 46.07  ? 314 ASP A CG    1 
ATOM   2159 O OD1   . ASP A 1 314 ? 140.592 153.380 188.469 1.00 51.28  ? 314 ASP A OD1   1 
ATOM   2160 O OD2   . ASP A 1 314 ? 142.055 153.398 186.838 1.00 47.41  ? 314 ASP A OD2   1 
ATOM   2161 N N     . ALA A 1 315 ? 137.673 150.207 185.834 1.00 35.00  ? 315 ALA A N     1 
ATOM   2162 C CA    . ALA A 1 315 ? 136.620 149.632 185.004 1.00 34.82  ? 315 ALA A CA    1 
ATOM   2163 C C     . ALA A 1 315 ? 135.276 149.663 185.718 1.00 40.00  ? 315 ALA A C     1 
ATOM   2164 O O     . ALA A 1 315 ? 134.248 149.978 185.108 1.00 45.70  ? 315 ALA A O     1 
ATOM   2165 C CB    . ALA A 1 315 ? 136.981 148.202 184.612 1.00 33.81  ? 315 ALA A CB    1 
ATOM   2166 N N     . GLU A 1 316 ? 135.261 149.337 187.011 1.00 41.23  ? 316 GLU A N     1 
ATOM   2167 C CA    . GLU A 1 316 ? 134.009 149.353 187.758 1.00 47.98  ? 316 GLU A CA    1 
ATOM   2168 C C     . GLU A 1 316 ? 133.464 150.770 187.896 1.00 53.82  ? 316 GLU A C     1 
ATOM   2169 O O     . GLU A 1 316 ? 132.248 150.984 187.815 1.00 61.82  ? 316 GLU A O     1 
ATOM   2170 C CB    . GLU A 1 316 ? 134.207 148.711 189.130 1.00 52.31  ? 316 GLU A CB    1 
ATOM   2171 C CG    . GLU A 1 316 ? 132.930 148.154 189.736 1.00 64.68  ? 316 GLU A CG    1 
ATOM   2172 C CD    . GLU A 1 316 ? 132.343 147.017 188.919 1.00 76.17  ? 316 GLU A CD    1 
ATOM   2173 O OE1   . GLU A 1 316 ? 133.118 146.272 188.284 1.00 74.11  ? 316 GLU A OE1   1 
ATOM   2174 O OE2   . GLU A 1 316 ? 131.103 146.870 188.910 1.00 78.29  ? 316 GLU A OE2   1 
ATOM   2175 N N     . MET A 1 317 ? 134.347 151.751 188.101 1.00 47.71  ? 317 MET A N     1 
ATOM   2176 C CA    . MET A 1 317 ? 133.897 153.141 188.148 1.00 44.00  ? 317 MET A CA    1 
ATOM   2177 C C     . MET A 1 317 ? 133.333 153.591 186.803 1.00 46.23  ? 317 MET A C     1 
ATOM   2178 O O     . MET A 1 317 ? 132.317 154.296 186.753 1.00 54.60  ? 317 MET A O     1 
ATOM   2179 C CB    . MET A 1 317 ? 135.040 154.051 188.594 1.00 46.53  ? 317 MET A CB    1 
ATOM   2180 C CG    . MET A 1 317 ? 135.324 153.970 190.087 1.00 58.24  ? 317 MET A CG    1 
ATOM   2181 S SD    . MET A 1 317 ? 136.455 155.245 190.672 1.00 71.23  ? 317 MET A SD    1 
ATOM   2182 C CE    . MET A 1 317 ? 137.990 154.720 189.919 1.00 52.87  ? 317 MET A CE    1 
ATOM   2183 N N     . VAL A 1 318 ? 133.974 153.189 185.703 1.00 38.99  ? 318 VAL A N     1 
ATOM   2184 C CA    . VAL A 1 318 ? 133.449 153.501 184.375 1.00 32.17  ? 318 VAL A CA    1 
ATOM   2185 C C     . VAL A 1 318 ? 132.075 152.871 184.181 1.00 33.85  ? 318 VAL A C     1 
ATOM   2186 O O     . VAL A 1 318 ? 131.162 153.494 183.626 1.00 36.33  ? 318 VAL A O     1 
ATOM   2187 C CB    . VAL A 1 318 ? 134.442 153.049 183.291 1.00 30.97  ? 318 VAL A CB    1 
ATOM   2188 C CG1   . VAL A 1 318 ? 133.779 153.057 181.926 1.00 33.97  ? 318 VAL A CG1   1 
ATOM   2189 C CG2   . VAL A 1 318 ? 135.670 153.944 183.298 1.00 36.05  ? 318 VAL A CG2   1 
ATOM   2190 N N     . VAL A 1 319 ? 131.907 151.627 184.631 1.00 36.12  ? 319 VAL A N     1 
ATOM   2191 C CA    . VAL A 1 319 ? 130.607 150.965 184.528 1.00 37.68  ? 319 VAL A CA    1 
ATOM   2192 C C     . VAL A 1 319 ? 129.556 151.719 185.334 1.00 40.46  ? 319 VAL A C     1 
ATOM   2193 O O     . VAL A 1 319 ? 128.424 151.919 184.873 1.00 49.12  ? 319 VAL A O     1 
ATOM   2194 C CB    . VAL A 1 319 ? 130.718 149.495 184.973 1.00 40.98  ? 319 VAL A CB    1 
ATOM   2195 C CG1   . VAL A 1 319 ? 129.336 148.870 185.089 1.00 45.59  ? 319 VAL A CG1   1 
ATOM   2196 C CG2   . VAL A 1 319 ? 131.576 148.714 183.994 1.00 36.60  ? 319 VAL A CG2   1 
ATOM   2197 N N     . ASP A 1 320 ? 129.911 152.149 186.549 1.00 38.10  ? 320 ASP A N     1 
ATOM   2198 C CA    . ASP A 1 320 ? 128.961 152.886 187.378 1.00 40.75  ? 320 ASP A CA    1 
ATOM   2199 C C     . ASP A 1 320 ? 128.558 154.198 186.720 1.00 48.21  ? 320 ASP A C     1 
ATOM   2200 O O     . ASP A 1 320 ? 127.385 154.587 186.766 1.00 53.13  ? 320 ASP A O     1 
ATOM   2201 C CB    . ASP A 1 320 ? 129.553 153.141 188.763 1.00 46.38  ? 320 ASP A CB    1 
ATOM   2202 C CG    . ASP A 1 320 ? 129.743 151.866 189.556 1.00 65.82  ? 320 ASP A CG    1 
ATOM   2203 O OD1   . ASP A 1 320 ? 128.971 150.910 189.334 1.00 70.76  ? 320 ASP A OD1   1 
ATOM   2204 O OD2   . ASP A 1 320 ? 130.663 151.819 190.399 1.00 68.45  ? 320 ASP A OD2   1 
ATOM   2205 N N     . LEU A 1 321 ? 129.518 154.895 186.107 1.00 44.37  ? 321 LEU A N     1 
ATOM   2206 C CA    . LEU A 1 321 ? 129.187 156.108 185.365 1.00 34.54  ? 321 LEU A CA    1 
ATOM   2207 C C     . LEU A 1 321 ? 128.281 155.802 184.178 1.00 36.77  ? 321 LEU A C     1 
ATOM   2208 O O     . LEU A 1 321 ? 127.347 156.560 183.892 1.00 43.97  ? 321 LEU A O     1 
ATOM   2209 C CB    . LEU A 1 321 ? 130.464 156.803 184.901 1.00 28.71  ? 321 LEU A CB    1 
ATOM   2210 C CG    . LEU A 1 321 ? 131.364 157.325 186.017 1.00 27.94  ? 321 LEU A CG    1 
ATOM   2211 C CD1   . LEU A 1 321 ? 132.750 157.630 185.489 1.00 29.15  ? 321 LEU A CD1   1 
ATOM   2212 C CD2   . LEU A 1 321 ? 130.753 158.559 186.653 1.00 38.35  ? 321 LEU A CD2   1 
ATOM   2213 N N     . ALA A 1 322 ? 128.541 154.697 183.474 1.00 36.98  ? 322 ALA A N     1 
ATOM   2214 C CA    . ALA A 1 322 ? 127.733 154.346 182.310 1.00 38.15  ? 322 ALA A CA    1 
ATOM   2215 C C     . ALA A 1 322 ? 126.292 154.043 182.699 1.00 42.57  ? 322 ALA A C     1 
ATOM   2216 O O     . ALA A 1 322 ? 125.357 154.457 182.005 1.00 45.20  ? 322 ALA A O     1 
ATOM   2217 C CB    . ALA A 1 322 ? 128.346 153.154 181.579 1.00 34.17  ? 322 ALA A CB    1 
ATOM   2218 N N     . GLN A 1 323 ? 126.091 153.313 183.797 1.00 43.87  ? 323 GLN A N     1 
ATOM   2219 C CA    . GLN A 1 323 ? 124.734 152.993 184.225 1.00 45.41  ? 323 GLN A CA    1 
ATOM   2220 C C     . GLN A 1 323 ? 124.017 154.193 184.827 1.00 50.26  ? 323 GLN A C     1 
ATOM   2221 O O     . GLN A 1 323 ? 122.790 154.159 184.965 1.00 56.09  ? 323 GLN A O     1 
ATOM   2222 C CB    . GLN A 1 323 ? 124.747 151.842 185.232 1.00 47.61  ? 323 GLN A CB    1 
ATOM   2223 C CG    . GLN A 1 323 ? 125.113 150.494 184.633 1.00 50.81  ? 323 GLN A CG    1 
ATOM   2224 C CD    . GLN A 1 323 ? 124.968 149.358 185.625 1.00 61.19  ? 323 GLN A CD    1 
ATOM   2225 O OE1   . GLN A 1 323 ? 124.739 149.581 186.813 1.00 67.97  ? 323 GLN A OE1   1 
ATOM   2226 N NE2   . GLN A 1 323 ? 125.099 148.129 185.139 1.00 61.74  ? 323 GLN A NE2   1 
ATOM   2227 N N     . ALA A 1 324 ? 124.750 155.245 185.194 1.00 44.51  ? 324 ALA A N     1 
ATOM   2228 C CA    . ALA A 1 324 ? 124.129 156.431 185.771 1.00 47.08  ? 324 ALA A CA    1 
ATOM   2229 C C     . ALA A 1 324 ? 123.499 157.344 184.726 1.00 53.65  ? 324 ALA A C     1 
ATOM   2230 O O     . ALA A 1 324 ? 122.683 158.201 185.084 1.00 59.29  ? 324 ALA A O     1 
ATOM   2231 C CB    . ALA A 1 324 ? 125.159 157.217 186.584 1.00 42.80  ? 324 ALA A CB    1 
ATOM   2232 N N     . MET A 1 325 ? 123.849 157.183 183.449 1.00 49.61  ? 325 MET A N     1 
ATOM   2233 C CA    . MET A 1 325 ? 123.370 158.105 182.425 1.00 49.36  ? 325 MET A CA    1 
ATOM   2234 C C     . MET A 1 325 ? 121.925 157.843 182.020 1.00 56.57  ? 325 MET A C     1 
ATOM   2235 O O     . MET A 1 325 ? 121.220 158.780 181.629 1.00 63.36  ? 325 MET A O     1 
ATOM   2236 C CB    . MET A 1 325 ? 124.273 158.035 181.197 1.00 37.83  ? 325 MET A CB    1 
ATOM   2237 C CG    . MET A 1 325 ? 125.711 158.404 181.487 1.00 38.79  ? 325 MET A CG    1 
ATOM   2238 S SD    . MET A 1 325 ? 126.762 158.184 180.051 1.00 37.57  ? 325 MET A SD    1 
ATOM   2239 C CE    . MET A 1 325 ? 126.313 156.522 179.569 1.00 35.31  ? 325 MET A CE    1 
ATOM   2240 N N     . GLY A 1 326 ? 121.466 156.598 182.097 1.00 53.93  ? 326 GLY A N     1 
ATOM   2241 C CA    . GLY A 1 326 ? 120.122 156.257 181.693 1.00 58.57  ? 326 GLY A CA    1 
ATOM   2242 C C     . GLY A 1 326 ? 119.996 155.958 180.212 1.00 64.48  ? 326 GLY A C     1 
ATOM   2243 O O     . GLY A 1 326 ? 120.923 156.177 179.426 1.00 61.26  ? 326 GLY A O     1 
ATOM   2244 N N     . PRO A 1 327 ? 118.833 155.445 179.807 1.00 72.86  ? 327 PRO A N     1 
ATOM   2245 C CA    . PRO A 1 327 ? 118.651 155.030 178.410 1.00 69.52  ? 327 PRO A CA    1 
ATOM   2246 C C     . PRO A 1 327 ? 118.769 156.199 177.444 1.00 64.04  ? 327 PRO A C     1 
ATOM   2247 O O     . PRO A 1 327 ? 118.465 157.346 177.778 1.00 67.26  ? 327 PRO A O     1 
ATOM   2248 C CB    . PRO A 1 327 ? 117.235 154.438 178.395 1.00 71.84  ? 327 PRO A CB    1 
ATOM   2249 C CG    . PRO A 1 327 ? 116.940 154.106 179.823 1.00 70.87  ? 327 PRO A CG    1 
ATOM   2250 C CD    . PRO A 1 327 ? 117.643 155.158 180.624 1.00 69.41  ? 327 PRO A CD    1 
ATOM   2251 N N     . LEU A 1 328 ? 119.223 155.892 176.232 1.00 57.79  ? 328 LEU A N     1 
ATOM   2252 C CA    . LEU A 1 328 ? 119.332 156.895 175.184 1.00 61.91  ? 328 LEU A CA    1 
ATOM   2253 C C     . LEU A 1 328 ? 117.987 157.113 174.502 1.00 64.94  ? 328 LEU A C     1 
ATOM   2254 O O     . LEU A 1 328 ? 117.213 156.173 174.305 1.00 57.00  ? 328 LEU A O     1 
ATOM   2255 C CB    . LEU A 1 328 ? 120.377 156.481 174.150 1.00 45.82  ? 328 LEU A CB    1 
ATOM   2256 C CG    . LEU A 1 328 ? 121.807 156.352 174.670 1.00 38.56  ? 328 LEU A CG    1 
ATOM   2257 C CD1   . LEU A 1 328 ? 122.780 156.216 173.521 1.00 32.85  ? 328 LEU A CD1   1 
ATOM   2258 C CD2   . LEU A 1 328 ? 122.175 157.544 175.542 1.00 40.46  ? 328 LEU A CD2   1 
ATOM   2259 N N     . LYS A 1 329 ? 117.719 158.364 174.138 1.00 68.76  ? 329 LYS A N     1 
ATOM   2260 C CA    . LYS A 1 329 ? 116.474 158.724 173.466 1.00 67.67  ? 329 LYS A CA    1 
ATOM   2261 C C     . LYS A 1 329 ? 116.464 158.246 172.018 1.00 59.45  ? 329 LYS A C     1 
ATOM   2262 O O     . LYS A 1 329 ? 115.789 158.828 171.169 1.00 57.02  ? 329 LYS A O     1 
ATOM   2263 C CB    . LYS A 1 329 ? 116.253 160.238 173.517 1.00 64.56  ? 329 LYS A CB    1 
ATOM   2264 C CG    . LYS A 1 329 ? 115.370 160.711 174.665 1.00 66.58  ? 329 LYS A CG    1 
ATOM   2265 C CD    . LYS A 1 329 ? 115.962 160.359 176.019 1.00 71.20  ? 329 LYS A CD    1 
ATOM   2266 C CE    . LYS A 1 329 ? 117.300 161.045 176.230 1.00 72.81  ? 329 LYS A CE    1 
ATOM   2267 N NZ    . LYS A 1 329 ? 117.894 160.695 177.548 1.00 75.63  ? 329 LYS A NZ    1 
ATOM   2268 N N     . GLU A 1 338 ? 115.041 147.750 176.364 1.00 70.70  ? 338 GLU A N     1 
ATOM   2269 C CA    . GLU A 1 338 ? 116.482 147.815 176.153 1.00 68.63  ? 338 GLU A CA    1 
ATOM   2270 C C     . GLU A 1 338 ? 117.233 147.961 177.471 1.00 68.61  ? 338 GLU A C     1 
ATOM   2271 O O     . GLU A 1 338 ? 116.888 148.798 178.305 1.00 71.01  ? 338 GLU A O     1 
ATOM   2272 C CB    . GLU A 1 338 ? 116.837 148.974 175.220 1.00 60.62  ? 338 GLU A CB    1 
ATOM   2273 C CG    . GLU A 1 338 ? 118.327 149.256 175.128 1.00 57.13  ? 338 GLU A CG    1 
ATOM   2274 C CD    . GLU A 1 338 ? 118.651 150.396 174.184 1.00 61.39  ? 338 GLU A CD    1 
ATOM   2275 O OE1   . GLU A 1 338 ? 117.882 150.613 173.225 1.00 61.10  ? 338 GLU A OE1   1 
ATOM   2276 O OE2   . GLU A 1 338 ? 119.673 151.078 174.406 1.00 60.39  ? 338 GLU A OE2   1 
ATOM   2277 N N     . GLN A 1 339 ? 118.264 147.139 177.651 1.00 67.32  ? 339 GLN A N     1 
ATOM   2278 C CA    . GLN A 1 339 ? 119.115 147.194 178.828 1.00 63.77  ? 339 GLN A CA    1 
ATOM   2279 C C     . GLN A 1 339 ? 120.566 147.332 178.395 1.00 56.65  ? 339 GLN A C     1 
ATOM   2280 O O     . GLN A 1 339 ? 120.964 146.844 177.334 1.00 52.15  ? 339 GLN A O     1 
ATOM   2281 C CB    . GLN A 1 339 ? 118.945 145.949 179.709 1.00 68.68  ? 339 GLN A CB    1 
ATOM   2282 C CG    . GLN A 1 339 ? 117.560 145.804 180.322 1.00 76.74  ? 339 GLN A CG    1 
ATOM   2283 C CD    . GLN A 1 339 ? 117.253 146.884 181.343 1.00 80.40  ? 339 GLN A CD    1 
ATOM   2284 O OE1   . GLN A 1 339 ? 118.157 147.523 181.883 1.00 78.57  ? 339 GLN A OE1   1 
ATOM   2285 N NE2   . GLN A 1 339 ? 115.969 147.094 181.612 1.00 79.37  ? 339 GLN A NE2   1 
ATOM   2286 N N     . LEU A 1 340 ? 121.350 148.014 179.223 1.00 52.34  ? 340 LEU A N     1 
ATOM   2287 C CA    . LEU A 1 340 ? 122.755 148.245 178.925 1.00 44.42  ? 340 LEU A CA    1 
ATOM   2288 C C     . LEU A 1 340 ? 123.581 147.003 179.238 1.00 41.79  ? 340 LEU A C     1 
ATOM   2289 O O     . LEU A 1 340 ? 123.306 146.280 180.199 1.00 49.30  ? 340 LEU A O     1 
ATOM   2290 C CB    . LEU A 1 340 ? 123.272 149.445 179.719 1.00 44.46  ? 340 LEU A CB    1 
ATOM   2291 C CG    . LEU A 1 340 ? 124.701 149.919 179.446 1.00 42.35  ? 340 LEU A CG    1 
ATOM   2292 C CD1   . LEU A 1 340 ? 124.754 151.434 179.456 1.00 37.77  ? 340 LEU A CD1   1 
ATOM   2293 C CD2   . LEU A 1 340 ? 125.662 149.351 180.473 1.00 43.05  ? 340 LEU A CD2   1 
ATOM   2294 N N     . ASP A 1 341 ? 124.597 146.759 178.414 1.00 34.22  ? 341 ASP A N     1 
ATOM   2295 C CA    . ASP A 1 341 ? 125.507 145.628 178.589 1.00 29.15  ? 341 ASP A CA    1 
ATOM   2296 C C     . ASP A 1 341 ? 126.652 146.079 179.487 1.00 34.16  ? 341 ASP A C     1 
ATOM   2297 O O     . ASP A 1 341 ? 127.586 146.741 179.032 1.00 39.36  ? 341 ASP A O     1 
ATOM   2298 C CB    . ASP A 1 341 ? 126.019 145.146 177.236 1.00 27.49  ? 341 ASP A CB    1 
ATOM   2299 C CG    . ASP A 1 341 ? 126.769 143.831 177.322 1.00 35.10  ? 341 ASP A CG    1 
ATOM   2300 O OD1   . ASP A 1 341 ? 127.219 143.454 178.424 1.00 38.10  ? 341 ASP A OD1   1 
ATOM   2301 O OD2   . ASP A 1 341 ? 126.913 143.168 176.274 1.00 44.78  ? 341 ASP A OD2   1 
ATOM   2302 N N     . GLU A 1 342 ? 126.592 145.710 180.769 1.00 34.34  ? 342 GLU A N     1 
ATOM   2303 C CA    . GLU A 1 342 ? 127.641 146.134 181.690 1.00 35.70  ? 342 GLU A CA    1 
ATOM   2304 C C     . GLU A 1 342 ? 128.951 145.395 181.436 1.00 34.19  ? 342 GLU A C     1 
ATOM   2305 O O     . GLU A 1 342 ? 130.028 145.952 181.675 1.00 38.95  ? 342 GLU A O     1 
ATOM   2306 C CB    . GLU A 1 342 ? 127.188 145.945 183.139 1.00 36.70  ? 342 GLU A CB    1 
ATOM   2307 C CG    . GLU A 1 342 ? 127.140 144.503 183.613 1.00 50.57  ? 342 GLU A CG    1 
ATOM   2308 C CD    . GLU A 1 342 ? 126.921 144.395 185.109 1.00 64.14  ? 342 GLU A CD    1 
ATOM   2309 O OE1   . GLU A 1 342 ? 126.006 145.067 185.629 1.00 73.59  ? 342 GLU A OE1   1 
ATOM   2310 O OE2   . GLU A 1 342 ? 127.674 143.647 185.768 1.00 59.60  ? 342 GLU A OE2   1 
ATOM   2311 N N     . ALA A 1 343 ? 128.885 144.153 180.951 1.00 29.40  ? 343 ALA A N     1 
ATOM   2312 C CA    . ALA A 1 343 ? 130.105 143.408 180.658 1.00 26.87  ? 343 ALA A CA    1 
ATOM   2313 C C     . ALA A 1 343 ? 130.854 144.017 179.481 1.00 30.02  ? 343 ALA A C     1 
ATOM   2314 O O     . ALA A 1 343 ? 132.089 144.090 179.492 1.00 34.13  ? 343 ALA A O     1 
ATOM   2315 C CB    . ALA A 1 343 ? 129.775 141.943 180.385 1.00 32.19  ? 343 ALA A CB    1 
ATOM   2316 N N     . LEU A 1 344 ? 130.123 144.452 178.455 1.00 31.75  ? 344 LEU A N     1 
ATOM   2317 C CA    . LEU A 1 344 ? 130.748 145.131 177.326 1.00 29.66  ? 344 LEU A CA    1 
ATOM   2318 C C     . LEU A 1 344 ? 131.411 146.429 177.769 1.00 27.79  ? 344 LEU A C     1 
ATOM   2319 O O     . LEU A 1 344 ? 132.542 146.733 177.371 1.00 30.28  ? 344 LEU A O     1 
ATOM   2320 C CB    . LEU A 1 344 ? 129.700 145.395 176.245 1.00 33.64  ? 344 LEU A CB    1 
ATOM   2321 C CG    . LEU A 1 344 ? 130.168 146.078 174.965 1.00 38.31  ? 344 LEU A CG    1 
ATOM   2322 C CD1   . LEU A 1 344 ? 131.186 145.208 174.254 1.00 39.96  ? 344 LEU A CD1   1 
ATOM   2323 C CD2   . LEU A 1 344 ? 128.985 146.380 174.056 1.00 33.65  ? 344 LEU A CD2   1 
ATOM   2324 N N     . VAL A 1 345 ? 130.713 147.210 178.595 1.00 25.54  ? 345 VAL A N     1 
ATOM   2325 C CA    . VAL A 1 345 ? 131.274 148.454 179.111 1.00 22.97  ? 345 VAL A CA    1 
ATOM   2326 C C     . VAL A 1 345 ? 132.534 148.175 179.919 1.00 27.29  ? 345 VAL A C     1 
ATOM   2327 O O     . VAL A 1 345 ? 133.530 148.900 179.813 1.00 31.45  ? 345 VAL A O     1 
ATOM   2328 C CB    . VAL A 1 345 ? 130.217 149.208 179.940 1.00 23.20  ? 345 VAL A CB    1 
ATOM   2329 C CG1   . VAL A 1 345 ? 130.807 150.464 180.549 1.00 27.32  ? 345 VAL A CG1   1 
ATOM   2330 C CG2   . VAL A 1 345 ? 129.017 149.550 179.076 1.00 27.61  ? 345 VAL A CG2   1 
ATOM   2331 N N     . ARG A 1 346 ? 132.518 147.115 180.730 1.00 27.53  ? 346 ARG A N     1 
ATOM   2332 C CA    . ARG A 1 346 ? 133.685 146.776 181.539 1.00 28.22  ? 346 ARG A CA    1 
ATOM   2333 C C     . ARG A 1 346 ? 134.865 146.345 180.673 1.00 26.38  ? 346 ARG A C     1 
ATOM   2334 O O     . ARG A 1 346 ? 136.006 146.743 180.929 1.00 29.44  ? 346 ARG A O     1 
ATOM   2335 C CB    . ARG A 1 346 ? 133.312 145.683 182.537 1.00 31.07  ? 346 ARG A CB    1 
ATOM   2336 C CG    . ARG A 1 346 ? 134.360 145.386 183.583 1.00 33.56  ? 346 ARG A CG    1 
ATOM   2337 C CD    . ARG A 1 346 ? 133.679 144.992 184.873 1.00 33.90  ? 346 ARG A CD    1 
ATOM   2338 N NE    . ARG A 1 346 ? 132.528 144.133 184.623 1.00 37.85  ? 346 ARG A NE    1 
ATOM   2339 C CZ    . ARG A 1 346 ? 131.584 143.867 185.513 1.00 49.72  ? 346 ARG A CZ    1 
ATOM   2340 N NH1   . ARG A 1 346 ? 131.605 144.401 186.723 1.00 49.81  ? 346 ARG A NH1   1 
ATOM   2341 N NH2   . ARG A 1 346 ? 130.592 143.045 185.182 1.00 56.28  ? 346 ARG A NH2   1 
ATOM   2342 N N     . THR A 1 347 ? 134.612 145.535 179.644 1.00 24.90  ? 347 THR A N     1 
ATOM   2343 C CA    . THR A 1 347 ? 135.684 145.132 178.737 1.00 22.81  ? 347 THR A CA    1 
ATOM   2344 C C     . THR A 1 347 ? 136.271 146.333 178.007 1.00 30.57  ? 347 THR A C     1 
ATOM   2345 O O     . THR A 1 347 ? 137.496 146.444 177.855 1.00 33.74  ? 347 THR A O     1 
ATOM   2346 C CB    . THR A 1 347 ? 135.159 144.101 177.739 1.00 28.91  ? 347 THR A CB    1 
ATOM   2347 O OG1   . THR A 1 347 ? 134.828 142.890 178.429 1.00 35.09  ? 347 THR A OG1   1 
ATOM   2348 C CG2   . THR A 1 347 ? 136.196 143.808 176.674 1.00 33.55  ? 347 THR A CG2   1 
ATOM   2349 N N     . VAL A 1 348 ? 135.411 147.246 177.547 1.00 35.35  ? 348 VAL A N     1 
ATOM   2350 C CA    . VAL A 1 348 ? 135.896 148.451 176.878 1.00 29.17  ? 348 VAL A CA    1 
ATOM   2351 C C     . VAL A 1 348 ? 136.734 149.287 177.834 1.00 31.50  ? 348 VAL A C     1 
ATOM   2352 O O     . VAL A 1 348 ? 137.800 149.793 177.469 1.00 36.00  ? 348 VAL A O     1 
ATOM   2353 C CB    . VAL A 1 348 ? 134.724 149.263 176.302 1.00 21.19  ? 348 VAL A CB    1 
ATOM   2354 C CG1   . VAL A 1 348 ? 135.230 150.583 175.760 1.00 25.20  ? 348 VAL A CG1   1 
ATOM   2355 C CG2   . VAL A 1 348 ? 134.037 148.480 175.214 1.00 24.65  ? 348 VAL A CG2   1 
ATOM   2356 N N     . ALA A 1 349 ? 136.257 149.462 179.068 1.00 29.13  ? 349 ALA A N     1 
ATOM   2357 C CA    . ALA A 1 349 ? 137.012 150.229 180.052 1.00 26.01  ? 349 ALA A CA    1 
ATOM   2358 C C     . ALA A 1 349 ? 138.379 149.606 180.298 1.00 23.57  ? 349 ALA A C     1 
ATOM   2359 O O     . ALA A 1 349 ? 139.388 150.310 180.401 1.00 27.63  ? 349 ALA A O     1 
ATOM   2360 C CB    . ALA A 1 349 ? 136.224 150.328 181.357 1.00 26.85  ? 349 ALA A CB    1 
ATOM   2361 N N     . LEU A 1 350 ? 138.425 148.278 180.404 1.00 22.46  ? 350 LEU A N     1 
ATOM   2362 C CA    . LEU A 1 350 ? 139.688 147.600 180.667 1.00 23.60  ? 350 LEU A CA    1 
ATOM   2363 C C     . LEU A 1 350 ? 140.660 147.751 179.502 1.00 26.10  ? 350 LEU A C     1 
ATOM   2364 O O     . LEU A 1 350 ? 141.853 147.994 179.713 1.00 31.49  ? 350 LEU A O     1 
ATOM   2365 C CB    . LEU A 1 350 ? 139.432 146.125 180.973 1.00 24.99  ? 350 LEU A CB    1 
ATOM   2366 C CG    . LEU A 1 350 ? 138.766 145.796 182.311 1.00 23.38  ? 350 LEU A CG    1 
ATOM   2367 C CD1   . LEU A 1 350 ? 138.418 144.320 182.402 1.00 23.67  ? 350 LEU A CD1   1 
ATOM   2368 C CD2   . LEU A 1 350 ? 139.663 146.193 183.455 1.00 21.82  ? 350 LEU A CD2   1 
ATOM   2369 N N     . SER A 1 351 ? 140.175 147.605 178.269 1.00 24.67  ? 351 SER A N     1 
ATOM   2370 C CA    . SER A 1 351 ? 141.057 147.631 177.107 1.00 28.92  ? 351 SER A CA    1 
ATOM   2371 C C     . SER A 1 351 ? 141.344 149.035 176.579 1.00 35.46  ? 351 SER A C     1 
ATOM   2372 O O     . SER A 1 351 ? 142.225 149.184 175.725 1.00 37.35  ? 351 SER A O     1 
ATOM   2373 C CB    . SER A 1 351 ? 140.461 146.779 175.984 1.00 33.83  ? 351 SER A CB    1 
ATOM   2374 O OG    . SER A 1 351 ? 139.189 147.265 175.592 1.00 33.55  ? 351 SER A OG    1 
ATOM   2375 N N     . SER A 1 352 ? 140.630 150.057 177.060 1.00 36.44  ? 352 SER A N     1 
ATOM   2376 C CA    . SER A 1 352 ? 140.694 151.385 176.457 1.00 33.75  ? 352 SER A CA    1 
ATOM   2377 C C     . SER A 1 352 ? 142.057 152.055 176.578 1.00 35.09  ? 352 SER A C     1 
ATOM   2378 O O     . SER A 1 352 ? 142.316 153.029 175.863 1.00 40.39  ? 352 SER A O     1 
ATOM   2379 C CB    . SER A 1 352 ? 139.629 152.281 177.088 1.00 28.18  ? 352 SER A CB    1 
ATOM   2380 O OG    . SER A 1 352 ? 139.873 152.452 178.472 1.00 25.21  ? 352 SER A OG    1 
ATOM   2381 N N     . ALA A 1 353 ? 142.930 151.574 177.453 1.00 33.74  ? 353 ALA A N     1 
ATOM   2382 C CA    . ALA A 1 353 ? 144.162 152.288 177.761 1.00 36.55  ? 353 ALA A CA    1 
ATOM   2383 C C     . ALA A 1 353 ? 145.223 152.180 176.668 1.00 32.20  ? 353 ALA A C     1 
ATOM   2384 O O     . ALA A 1 353 ? 146.374 152.556 176.910 1.00 37.15  ? 353 ALA A O     1 
ATOM   2385 C CB    . ALA A 1 353 ? 144.733 151.785 179.090 1.00 40.53  ? 353 ALA A CB    1 
ATOM   2386 N N     . GLY A 1 354 ? 144.879 151.689 175.482 1.00 30.24  ? 354 GLY A N     1 
ATOM   2387 C CA    . GLY A 1 354 ? 145.870 151.533 174.437 1.00 35.71  ? 354 GLY A CA    1 
ATOM   2388 C C     . GLY A 1 354 ? 145.592 152.287 173.152 1.00 43.54  ? 354 GLY A C     1 
ATOM   2389 O O     . GLY A 1 354 ? 144.477 152.767 172.923 1.00 42.96  ? 354 GLY A O     1 
ATOM   2390 N N     . GLY A 1 355 ? 146.615 152.402 172.310 1.00 41.45  ? 355 GLY A N     1 
ATOM   2391 C CA    . GLY A 1 355 ? 146.469 152.924 170.968 1.00 38.18  ? 355 GLY A CA    1 
ATOM   2392 C C     . GLY A 1 355 ? 147.096 151.970 169.975 1.00 41.63  ? 355 GLY A C     1 
ATOM   2393 O O     . GLY A 1 355 ? 148.304 151.719 170.029 1.00 39.55  ? 355 GLY A O     1 
ATOM   2394 N N     . LEU A 1 356 ? 146.294 151.424 169.067 1.00 44.86  ? 356 LEU A N     1 
ATOM   2395 C CA    . LEU A 1 356 ? 146.720 150.338 168.195 1.00 41.88  ? 356 LEU A CA    1 
ATOM   2396 C C     . LEU A 1 356 ? 146.855 150.817 166.757 1.00 36.88  ? 356 LEU A C     1 
ATOM   2397 O O     . LEU A 1 356 ? 146.027 151.593 166.271 1.00 38.99  ? 356 LEU A O     1 
ATOM   2398 C CB    . LEU A 1 356 ? 145.736 149.170 168.263 1.00 35.59  ? 356 LEU A CB    1 
ATOM   2399 C CG    . LEU A 1 356 ? 145.593 148.575 169.663 1.00 32.61  ? 356 LEU A CG    1 
ATOM   2400 C CD1   . LEU A 1 356 ? 144.551 147.488 169.684 1.00 31.98  ? 356 LEU A CD1   1 
ATOM   2401 C CD2   . LEU A 1 356 ? 146.930 148.041 170.138 1.00 31.89  ? 356 LEU A CD2   1 
ATOM   2402 N N     . SER A 1 357 ? 147.904 150.343 166.084 1.00 30.98  ? 357 SER A N     1 
ATOM   2403 C CA    . SER A 1 357 ? 148.121 150.709 164.685 1.00 25.90  ? 357 SER A CA    1 
ATOM   2404 C C     . SER A 1 357 ? 146.984 150.280 163.765 1.00 33.63  ? 357 SER A C     1 
ATOM   2405 O O     . SER A 1 357 ? 146.543 151.107 162.949 1.00 36.40  ? 357 SER A O     1 
ATOM   2406 C CB    . SER A 1 357 ? 149.461 150.145 164.207 1.00 24.85  ? 357 SER A CB    1 
ATOM   2407 O OG    . SER A 1 357 ? 149.649 150.406 162.827 1.00 30.66  ? 357 SER A OG    1 
ATOM   2408 N N     . PRO A 1 358 ? 146.485 149.034 163.804 1.00 32.51  ? 358 PRO A N     1 
ATOM   2409 C CA    . PRO A 1 358 ? 145.359 148.689 162.917 1.00 27.70  ? 358 PRO A CA    1 
ATOM   2410 C C     . PRO A 1 358 ? 144.109 149.506 163.176 1.00 29.89  ? 358 PRO A C     1 
ATOM   2411 O O     . PRO A 1 358 ? 143.415 149.895 162.226 1.00 35.22  ? 358 PRO A O     1 
ATOM   2412 C CB    . PRO A 1 358 ? 145.126 147.202 163.215 1.00 28.45  ? 358 PRO A CB    1 
ATOM   2413 C CG    . PRO A 1 358 ? 146.389 146.725 163.776 1.00 29.98  ? 358 PRO A CG    1 
ATOM   2414 C CD    . PRO A 1 358 ? 146.935 147.858 164.568 1.00 31.66  ? 358 PRO A CD    1 
ATOM   2415 N N     . MET A 1 359 ? 143.796 149.772 164.444 1.00 25.41  ? 359 MET A N     1 
ATOM   2416 C CA    . MET A 1 359 ? 142.626 150.583 164.753 1.00 27.49  ? 359 MET A CA    1 
ATOM   2417 C C     . MET A 1 359 ? 142.796 151.997 164.224 1.00 31.07  ? 359 MET A C     1 
ATOM   2418 O O     . MET A 1 359 ? 141.868 152.567 163.632 1.00 36.16  ? 359 MET A O     1 
ATOM   2419 C CB    . MET A 1 359 ? 142.382 150.592 166.259 1.00 30.42  ? 359 MET A CB    1 
ATOM   2420 C CG    . MET A 1 359 ? 141.983 149.245 166.820 1.00 31.83  ? 359 MET A CG    1 
ATOM   2421 S SD    . MET A 1 359 ? 140.322 148.775 166.320 1.00 32.04  ? 359 MET A SD    1 
ATOM   2422 C CE    . MET A 1 359 ? 139.393 150.147 166.989 1.00 27.45  ? 359 MET A CE    1 
ATOM   2423 N N     . ALA A 1 360 ? 143.986 152.569 164.421 1.00 28.69  ? 360 ALA A N     1 
ATOM   2424 C CA    . ALA A 1 360 ? 144.290 153.877 163.860 1.00 27.50  ? 360 ALA A CA    1 
ATOM   2425 C C     . ALA A 1 360 ? 144.107 153.870 162.350 1.00 31.06  ? 360 ALA A C     1 
ATOM   2426 O O     . ALA A 1 360 ? 143.475 154.767 161.790 1.00 33.92  ? 360 ALA A O     1 
ATOM   2427 C CB    . ALA A 1 360 ? 145.713 154.287 164.234 1.00 25.58  ? 360 ALA A CB    1 
ATOM   2428 N N     . ALA A 1 361 ? 144.627 152.844 161.678 1.00 30.82  ? 361 ALA A N     1 
ATOM   2429 C CA    . ALA A 1 361 ? 144.535 152.785 160.223 1.00 28.16  ? 361 ALA A CA    1 
ATOM   2430 C C     . ALA A 1 361 ? 143.084 152.736 159.761 1.00 26.00  ? 361 ALA A C     1 
ATOM   2431 O O     . ALA A 1 361 ? 142.670 153.525 158.906 1.00 30.44  ? 361 ALA A O     1 
ATOM   2432 C CB    . ALA A 1 361 ? 145.315 151.581 159.698 1.00 31.09  ? 361 ALA A CB    1 
ATOM   2433 N N     . VAL A 1 362 ? 142.285 151.840 160.343 1.00 24.25  ? 362 VAL A N     1 
ATOM   2434 C CA    . VAL A 1 362 ? 140.899 151.687 159.901 1.00 29.06  ? 362 VAL A CA    1 
ATOM   2435 C C     . VAL A 1 362 ? 140.111 152.969 160.148 1.00 30.85  ? 362 VAL A C     1 
ATOM   2436 O O     . VAL A 1 362 ? 139.469 153.519 159.237 1.00 39.34  ? 362 VAL A O     1 
ATOM   2437 C CB    . VAL A 1 362 ? 140.243 150.482 160.600 1.00 31.92  ? 362 VAL A CB    1 
ATOM   2438 C CG1   . VAL A 1 362 ? 138.766 150.425 160.272 1.00 32.63  ? 362 VAL A CG1   1 
ATOM   2439 C CG2   . VAL A 1 362 ? 140.926 149.193 160.189 1.00 30.81  ? 362 VAL A CG2   1 
ATOM   2440 N N     . LEU A 1 363 ? 140.166 153.483 161.381 1.00 26.74  ? 363 LEU A N     1 
ATOM   2441 C CA    . LEU A 1 363 ? 139.324 154.622 161.717 1.00 26.83  ? 363 LEU A CA    1 
ATOM   2442 C C     . LEU A 1 363 ? 139.804 155.898 161.037 1.00 31.37  ? 363 LEU A C     1 
ATOM   2443 O O     . LEU A 1 363 ? 138.981 156.735 160.648 1.00 33.55  ? 363 LEU A O     1 
ATOM   2444 C CB    . LEU A 1 363 ? 139.264 154.803 163.231 1.00 25.55  ? 363 LEU A CB    1 
ATOM   2445 C CG    . LEU A 1 363 ? 137.995 155.486 163.732 1.00 26.17  ? 363 LEU A CG    1 
ATOM   2446 C CD1   . LEU A 1 363 ? 136.807 154.544 163.632 1.00 22.34  ? 363 LEU A CD1   1 
ATOM   2447 C CD2   . LEU A 1 363 ? 138.173 155.981 165.156 1.00 30.45  ? 363 LEU A CD2   1 
ATOM   2448 N N     . GLY A 1 364 ? 141.116 156.056 160.849 1.00 31.06  ? 364 GLY A N     1 
ATOM   2449 C CA    . GLY A 1 364 ? 141.619 157.207 160.131 1.00 29.78  ? 364 GLY A CA    1 
ATOM   2450 C C     . GLY A 1 364 ? 141.333 157.142 158.651 1.00 32.76  ? 364 GLY A C     1 
ATOM   2451 O O     . GLY A 1 364 ? 141.124 158.175 158.017 1.00 38.96  ? 364 GLY A O     1 
ATOM   2452 N N     . ALA A 1 365 ? 141.299 155.937 158.081 1.00 27.62  ? 365 ALA A N     1 
ATOM   2453 C CA    . ALA A 1 365 ? 140.868 155.788 156.699 1.00 28.35  ? 365 ALA A CA    1 
ATOM   2454 C C     . ALA A 1 365 ? 139.420 156.226 156.534 1.00 28.06  ? 365 ALA A C     1 
ATOM   2455 O O     . ALA A 1 365 ? 139.081 156.972 155.605 1.00 38.31  ? 365 ALA A O     1 
ATOM   2456 C CB    . ALA A 1 365 ? 141.054 154.340 156.258 1.00 28.23  ? 365 ALA A CB    1 
ATOM   2457 N N     . VAL A 1 366 ? 138.552 155.797 157.451 1.00 23.22  ? 366 VAL A N     1 
ATOM   2458 C CA    . VAL A 1 366 ? 137.156 156.220 157.367 1.00 29.78  ? 366 VAL A CA    1 
ATOM   2459 C C     . VAL A 1 366 ? 137.038 157.731 157.544 1.00 36.13  ? 366 VAL A C     1 
ATOM   2460 O O     . VAL A 1 366 ? 136.321 158.407 156.791 1.00 38.94  ? 366 VAL A O     1 
ATOM   2461 C CB    . VAL A 1 366 ? 136.298 155.463 158.393 1.00 35.15  ? 366 VAL A CB    1 
ATOM   2462 C CG1   . VAL A 1 366 ? 134.848 155.868 158.242 1.00 37.69  ? 366 VAL A CG1   1 
ATOM   2463 C CG2   . VAL A 1 366 ? 136.453 153.966 158.207 1.00 34.46  ? 366 VAL A CG2   1 
ATOM   2464 N N     . ALA A 1 367 ? 137.745 158.287 158.532 1.00 32.62  ? 367 ALA A N     1 
ATOM   2465 C CA    . ALA A 1 367 ? 137.669 159.722 158.786 1.00 32.14  ? 367 ALA A CA    1 
ATOM   2466 C C     . ALA A 1 367 ? 138.218 160.528 157.615 1.00 33.97  ? 367 ALA A C     1 
ATOM   2467 O O     . ALA A 1 367 ? 137.685 161.591 157.281 1.00 41.40  ? 367 ALA A O     1 
ATOM   2468 C CB    . ALA A 1 367 ? 138.417 160.064 160.073 1.00 33.05  ? 367 ALA A CB    1 
ATOM   2469 N N     . ALA A 1 368 ? 139.283 160.041 156.979 1.00 29.04  ? 368 ALA A N     1 
ATOM   2470 C CA    . ALA A 1 368 ? 139.848 160.733 155.828 1.00 32.62  ? 368 ALA A CA    1 
ATOM   2471 C C     . ALA A 1 368 ? 138.901 160.688 154.642 1.00 36.23  ? 368 ALA A C     1 
ATOM   2472 O O     . ALA A 1 368 ? 138.760 161.680 153.917 1.00 43.95  ? 368 ALA A O     1 
ATOM   2473 C CB    . ALA A 1 368 ? 141.195 160.120 155.461 1.00 33.43  ? 368 ALA A CB    1 
ATOM   2474 N N     . GLN A 1 369 ? 138.240 159.549 154.427 1.00 33.98  ? 369 GLN A N     1 
ATOM   2475 C CA    . GLN A 1 369 ? 137.245 159.487 153.364 1.00 37.58  ? 369 GLN A CA    1 
ATOM   2476 C C     . GLN A 1 369 ? 136.094 160.449 153.635 1.00 40.62  ? 369 GLN A C     1 
ATOM   2477 O O     . GLN A 1 369 ? 135.582 161.089 152.709 1.00 45.56  ? 369 GLN A O     1 
ATOM   2478 C CB    . GLN A 1 369 ? 136.732 158.059 153.195 1.00 38.05  ? 369 GLN A CB    1 
ATOM   2479 C CG    . GLN A 1 369 ? 135.830 157.893 151.984 1.00 42.15  ? 369 GLN A CG    1 
ATOM   2480 C CD    . GLN A 1 369 ? 136.528 158.255 150.689 1.00 48.17  ? 369 GLN A CD    1 
ATOM   2481 O OE1   . GLN A 1 369 ? 137.628 157.782 150.411 1.00 54.00  ? 369 GLN A OE1   1 
ATOM   2482 N NE2   . GLN A 1 369 ? 135.895 159.104 149.891 1.00 45.32  ? 369 GLN A NE2   1 
ATOM   2483 N N     . GLU A 1 370 ? 135.675 160.574 154.898 1.00 34.56  ? 370 GLU A N     1 
ATOM   2484 C CA    . GLU A 1 370 ? 134.636 161.548 155.229 1.00 33.38  ? 370 GLU A CA    1 
ATOM   2485 C C     . GLU A 1 370 ? 135.117 162.980 155.000 1.00 37.83  ? 370 GLU A C     1 
ATOM   2486 O O     . GLU A 1 370 ? 134.351 163.835 154.536 1.00 43.61  ? 370 GLU A O     1 
ATOM   2487 C CB    . GLU A 1 370 ? 134.171 161.361 156.671 1.00 34.03  ? 370 GLU A CB    1 
ATOM   2488 C CG    . GLU A 1 370 ? 133.623 159.978 156.969 1.00 42.54  ? 370 GLU A CG    1 
ATOM   2489 C CD    . GLU A 1 370 ? 132.561 159.532 155.979 1.00 50.38  ? 370 GLU A CD    1 
ATOM   2490 O OE1   . GLU A 1 370 ? 131.639 160.323 155.688 1.00 54.83  ? 370 GLU A OE1   1 
ATOM   2491 O OE2   . GLU A 1 370 ? 132.651 158.387 155.490 1.00 48.15  ? 370 GLU A OE2   1 
ATOM   2492 N N     . VAL A 1 371 ? 136.379 163.261 155.329 1.00 38.10  ? 371 VAL A N     1 
ATOM   2493 C CA    . VAL A 1 371 ? 136.952 164.578 155.058 1.00 41.94  ? 371 VAL A CA    1 
ATOM   2494 C C     . VAL A 1 371 ? 136.900 164.878 153.567 1.00 43.32  ? 371 VAL A C     1 
ATOM   2495 O O     . VAL A 1 371 ? 136.531 165.982 153.149 1.00 44.60  ? 371 VAL A O     1 
ATOM   2496 C CB    . VAL A 1 371 ? 138.395 164.656 155.590 1.00 38.85  ? 371 VAL A CB    1 
ATOM   2497 C CG1   . VAL A 1 371 ? 139.097 165.890 155.050 1.00 37.13  ? 371 VAL A CG1   1 
ATOM   2498 C CG2   . VAL A 1 371 ? 138.409 164.663 157.103 1.00 39.95  ? 371 VAL A CG2   1 
ATOM   2499 N N     . LEU A 1 372 ? 137.271 163.899 152.745 1.00 40.98  ? 372 LEU A N     1 
ATOM   2500 C CA    . LEU A 1 372 ? 137.245 164.089 151.300 1.00 38.05  ? 372 LEU A CA    1 
ATOM   2501 C C     . LEU A 1 372 ? 135.820 164.259 150.789 1.00 39.57  ? 372 LEU A C     1 
ATOM   2502 O O     . LEU A 1 372 ? 135.581 165.026 149.850 1.00 48.90  ? 372 LEU A O     1 
ATOM   2503 C CB    . LEU A 1 372 ? 137.946 162.920 150.614 1.00 38.87  ? 372 LEU A CB    1 
ATOM   2504 C CG    . LEU A 1 372 ? 139.402 162.774 151.062 1.00 45.77  ? 372 LEU A CG    1 
ATOM   2505 C CD1   . LEU A 1 372 ? 139.871 161.330 150.957 1.00 48.13  ? 372 LEU A CD1   1 
ATOM   2506 C CD2   . LEU A 1 372 ? 140.310 163.703 150.273 1.00 53.96  ? 372 LEU A CD2   1 
ATOM   2507 N N     . LYS A 1 373 ? 134.862 163.548 151.389 1.00 36.37  ? 373 LYS A N     1 
ATOM   2508 C CA    . LYS A 1 373 ? 133.460 163.752 151.034 1.00 38.63  ? 373 LYS A CA    1 
ATOM   2509 C C     . LYS A 1 373 ? 133.028 165.181 151.323 1.00 40.76  ? 373 LYS A C     1 
ATOM   2510 O O     . LYS A 1 373 ? 132.321 165.800 150.521 1.00 46.69  ? 373 LYS A O     1 
ATOM   2511 C CB    . LYS A 1 373 ? 132.565 162.779 151.799 1.00 37.59  ? 373 LYS A CB    1 
ATOM   2512 C CG    . LYS A 1 373 ? 132.702 161.325 151.408 1.00 42.49  ? 373 LYS A CG    1 
ATOM   2513 C CD    . LYS A 1 373 ? 131.805 160.469 152.283 1.00 45.32  ? 373 LYS A CD    1 
ATOM   2514 C CE    . LYS A 1 373 ? 132.040 158.991 152.056 1.00 45.80  ? 373 LYS A CE    1 
ATOM   2515 N NZ    . LYS A 1 373 ? 131.204 158.181 152.976 1.00 44.29  ? 373 LYS A NZ    1 
ATOM   2516 N N     . ALA A 1 374 ? 133.428 165.714 152.477 1.00 37.70  ? 374 ALA A N     1 
ATOM   2517 C CA    . ALA A 1 374 ? 133.089 167.096 152.805 1.00 39.86  ? 374 ALA A CA    1 
ATOM   2518 C C     . ALA A 1 374 ? 133.758 168.071 151.844 1.00 46.84  ? 374 ALA A C     1 
ATOM   2519 O O     . ALA A 1 374 ? 133.148 169.060 151.423 1.00 51.81  ? 374 ALA A O     1 
ATOM   2520 C CB    . ALA A 1 374 ? 133.487 167.408 154.247 1.00 36.84  ? 374 ALA A CB    1 
ATOM   2521 N N     . ILE A 1 375 ? 135.015 167.806 151.490 1.00 44.44  ? 375 ILE A N     1 
ATOM   2522 C CA    . ILE A 1 375 ? 135.773 168.729 150.651 1.00 38.17  ? 375 ILE A CA    1 
ATOM   2523 C C     . ILE A 1 375 ? 135.209 168.766 149.235 1.00 46.65  ? 375 ILE A C     1 
ATOM   2524 O O     . ILE A 1 375 ? 134.966 169.841 148.675 1.00 53.44  ? 375 ILE A O     1 
ATOM   2525 C CB    . ILE A 1 375 ? 137.261 168.340 150.652 1.00 36.41  ? 375 ILE A CB    1 
ATOM   2526 C CG1   . ILE A 1 375 ? 137.929 168.782 151.950 1.00 39.65  ? 375 ILE A CG1   1 
ATOM   2527 C CG2   . ILE A 1 375 ? 137.968 168.926 149.449 1.00 54.11  ? 375 ILE A CG2   1 
ATOM   2528 C CD1   . ILE A 1 375 ? 139.368 168.352 152.053 1.00 51.15  ? 375 ILE A CD1   1 
ATOM   2529 N N     . SER A 1 376 ? 134.985 167.596 148.638 1.00 44.69  ? 376 SER A N     1 
ATOM   2530 C CA    . SER A 1 376 ? 134.620 167.514 147.231 1.00 48.54  ? 376 SER A CA    1 
ATOM   2531 C C     . SER A 1 376 ? 133.123 167.375 146.996 1.00 50.02  ? 376 SER A C     1 
ATOM   2532 O O     . SER A 1 376 ? 132.681 167.491 145.848 1.00 63.28  ? 376 SER A O     1 
ATOM   2533 C CB    . SER A 1 376 ? 135.348 166.339 146.566 1.00 48.34  ? 376 SER A CB    1 
ATOM   2534 O OG    . SER A 1 376 ? 134.940 165.104 147.123 1.00 46.41  ? 376 SER A OG    1 
ATOM   2535 N N     . GLY A 1 377 ? 132.336 167.130 148.038 1.00 42.22  ? 377 GLY A N     1 
ATOM   2536 C CA    . GLY A 1 377 ? 130.906 166.988 147.886 1.00 44.98  ? 377 GLY A CA    1 
ATOM   2537 C C     . GLY A 1 377 ? 130.453 165.661 147.323 1.00 47.26  ? 377 GLY A C     1 
ATOM   2538 O O     . GLY A 1 377 ? 129.250 165.481 147.098 1.00 53.37  ? 377 GLY A O     1 
ATOM   2539 N N     . LYS A 1 378 ? 131.369 164.729 147.090 1.00 41.73  ? 378 LYS A N     1 
ATOM   2540 C CA    . LYS A 1 378 ? 131.022 163.450 146.499 1.00 48.39  ? 378 LYS A CA    1 
ATOM   2541 C C     . LYS A 1 378 ? 130.557 162.473 147.571 1.00 51.76  ? 378 LYS A C     1 
ATOM   2542 O O     . LYS A 1 378 ? 130.876 162.615 148.754 1.00 53.41  ? 378 LYS A O     1 
ATOM   2543 C CB    . LYS A 1 378 ? 132.220 162.871 145.746 1.00 54.97  ? 378 LYS A CB    1 
ATOM   2544 C CG    . LYS A 1 378 ? 131.856 161.947 144.599 1.00 62.25  ? 378 LYS A CG    1 
ATOM   2545 C CD    . LYS A 1 378 ? 133.098 161.352 143.949 1.00 61.38  ? 378 LYS A CD    1 
ATOM   2546 C CE    . LYS A 1 378 ? 134.108 162.425 143.569 1.00 65.02  ? 378 LYS A CE    1 
ATOM   2547 N NZ    . LYS A 1 378 ? 135.307 161.842 142.906 1.00 64.31  ? 378 LYS A NZ    1 
ATOM   2548 N N     . PHE A 1 379 ? 129.788 161.475 147.136 1.00 55.15  ? 379 PHE A N     1 
ATOM   2549 C CA    . PHE A 1 379 ? 129.298 160.391 147.983 1.00 49.49  ? 379 PHE A CA    1 
ATOM   2550 C C     . PHE A 1 379 ? 128.435 160.883 149.141 1.00 49.39  ? 379 PHE A C     1 
ATOM   2551 O O     . PHE A 1 379 ? 128.281 162.090 149.353 1.00 49.80  ? 379 PHE A O     1 
ATOM   2552 C CB    . PHE A 1 379 ? 130.469 159.573 148.526 1.00 43.48  ? 379 PHE A CB    1 
ATOM   2553 C CG    . PHE A 1 379 ? 131.405 159.073 147.469 1.00 45.72  ? 379 PHE A CG    1 
ATOM   2554 C CD1   . PHE A 1 379 ? 130.935 158.690 146.226 1.00 52.05  ? 379 PHE A CD1   1 
ATOM   2555 C CD2   . PHE A 1 379 ? 132.762 158.983 147.723 1.00 50.78  ? 379 PHE A CD2   1 
ATOM   2556 C CE1   . PHE A 1 379 ? 131.799 158.225 145.257 1.00 59.32  ? 379 PHE A CE1   1 
ATOM   2557 C CE2   . PHE A 1 379 ? 133.632 158.519 146.759 1.00 54.25  ? 379 PHE A CE2   1 
ATOM   2558 C CZ    . PHE A 1 379 ? 133.150 158.139 145.525 1.00 61.16  ? 379 PHE A CZ    1 
ATOM   2559 N N     . MET A 1 380 ? 127.859 159.948 149.882 1.00 48.22  ? 380 MET A N     1 
ATOM   2560 C CA    . MET A 1 380 ? 127.018 160.244 151.035 1.00 51.50  ? 380 MET A CA    1 
ATOM   2561 C C     . MET A 1 380 ? 127.845 160.172 152.314 1.00 54.18  ? 380 MET A C     1 
ATOM   2562 O O     . MET A 1 380 ? 128.542 159.175 152.536 1.00 50.76  ? 380 MET A O     1 
ATOM   2563 C CB    . MET A 1 380 ? 125.855 159.265 151.119 1.00 48.76  ? 380 MET A CB    1 
ATOM   2564 C CG    . MET A 1 380 ? 124.529 159.892 151.520 1.00 49.82  ? 380 MET A CG    1 
ATOM   2565 S SD    . MET A 1 380 ? 123.854 160.966 150.242 1.00 66.58  ? 380 MET A SD    1 
ATOM   2566 C CE    . MET A 1 380 ? 122.256 161.373 150.941 1.00 60.04  ? 380 MET A CE    1 
ATOM   2567 N N     . PRO A 1 381 ? 127.809 161.193 153.163 1.00 51.13  ? 381 PRO A N     1 
ATOM   2568 C CA    . PRO A 1 381 ? 128.540 161.136 154.430 1.00 44.69  ? 381 PRO A CA    1 
ATOM   2569 C C     . PRO A 1 381 ? 127.843 160.223 155.431 1.00 50.01  ? 381 PRO A C     1 
ATOM   2570 O O     . PRO A 1 381 ? 126.675 159.863 155.280 1.00 51.39  ? 381 PRO A O     1 
ATOM   2571 C CB    . PRO A 1 381 ? 128.521 162.589 154.906 1.00 37.42  ? 381 PRO A CB    1 
ATOM   2572 C CG    . PRO A 1 381 ? 127.263 163.136 154.335 1.00 33.98  ? 381 PRO A CG    1 
ATOM   2573 C CD    . PRO A 1 381 ? 127.089 162.468 152.999 1.00 45.00  ? 381 PRO A CD    1 
ATOM   2574 N N     . LEU A 1 382 ? 128.591 159.856 156.470 1.00 47.54  ? 382 LEU A N     1 
ATOM   2575 C CA    . LEU A 1 382 ? 128.019 159.096 157.573 1.00 42.79  ? 382 LEU A CA    1 
ATOM   2576 C C     . LEU A 1 382 ? 126.872 159.877 158.195 1.00 41.38  ? 382 LEU A C     1 
ATOM   2577 O O     . LEU A 1 382 ? 126.908 161.108 158.266 1.00 43.30  ? 382 LEU A O     1 
ATOM   2578 C CB    . LEU A 1 382 ? 129.086 158.802 158.627 1.00 41.57  ? 382 LEU A CB    1 
ATOM   2579 C CG    . LEU A 1 382 ? 130.035 157.642 158.337 1.00 50.01  ? 382 LEU A CG    1 
ATOM   2580 C CD1   . LEU A 1 382 ? 131.380 157.882 158.978 1.00 41.53  ? 382 LEU A CD1   1 
ATOM   2581 C CD2   . LEU A 1 382 ? 129.437 156.359 158.853 1.00 47.71  ? 382 LEU A CD2   1 
ATOM   2582 N N     . ASP A 1 383 ? 125.837 159.157 158.630 1.00 38.29  ? 383 ASP A N     1 
ATOM   2583 C CA    . ASP A 1 383 ? 124.647 159.827 159.136 1.00 36.02  ? 383 ASP A CA    1 
ATOM   2584 C C     . ASP A 1 383 ? 124.995 160.678 160.349 1.00 43.04  ? 383 ASP A C     1 
ATOM   2585 O O     . ASP A 1 383 ? 124.962 161.910 160.274 1.00 41.37  ? 383 ASP A O     1 
ATOM   2586 C CB    . ASP A 1 383 ? 123.566 158.808 159.492 1.00 41.74  ? 383 ASP A CB    1 
ATOM   2587 C CG    . ASP A 1 383 ? 123.030 158.075 158.277 1.00 61.62  ? 383 ASP A CG    1 
ATOM   2588 O OD1   . ASP A 1 383 ? 123.502 158.353 157.154 1.00 63.50  ? 383 ASP A OD1   1 
ATOM   2589 O OD2   . ASP A 1 383 ? 122.133 157.222 158.443 1.00 69.61  ? 383 ASP A OD2   1 
ATOM   2590 N N     . GLN A 1 384 ? 125.332 160.043 161.461 1.00 41.38  ? 384 GLN A N     1 
ATOM   2591 C CA    . GLN A 1 384 ? 125.922 160.789 162.567 1.00 29.46  ? 384 GLN A CA    1 
ATOM   2592 C C     . GLN A 1 384 ? 127.136 160.111 163.185 1.00 26.89  ? 384 GLN A C     1 
ATOM   2593 O O     . GLN A 1 384 ? 128.095 160.797 163.540 1.00 29.12  ? 384 GLN A O     1 
ATOM   2594 C CB    . GLN A 1 384 ? 124.859 161.050 163.644 1.00 30.52  ? 384 GLN A CB    1 
ATOM   2595 C CG    . GLN A 1 384 ? 123.873 162.154 163.291 1.00 30.53  ? 384 GLN A CG    1 
ATOM   2596 C CD    . GLN A 1 384 ? 124.505 163.531 163.297 1.00 29.07  ? 384 GLN A CD    1 
ATOM   2597 O OE1   . GLN A 1 384 ? 125.386 163.830 162.494 1.00 25.25  ? 384 GLN A OE1   1 
ATOM   2598 N NE2   . GLN A 1 384 ? 124.056 164.379 164.212 1.00 34.30  ? 384 GLN A NE2   1 
ATOM   2599 N N     . TRP A 1 385 ? 127.128 158.785 163.312 1.00 24.74  ? 385 TRP A N     1 
ATOM   2600 C CA    . TRP A 1 385 ? 128.136 158.090 164.099 1.00 21.07  ? 385 TRP A CA    1 
ATOM   2601 C C     . TRP A 1 385 ? 128.562 156.807 163.404 1.00 24.63  ? 385 TRP A C     1 
ATOM   2602 O O     . TRP A 1 385 ? 127.859 156.268 162.546 1.00 37.87  ? 385 TRP A O     1 
ATOM   2603 C CB    . TRP A 1 385 ? 127.631 157.741 165.506 1.00 20.17  ? 385 TRP A CB    1 
ATOM   2604 C CG    . TRP A 1 385 ? 127.230 158.903 166.359 1.00 22.28  ? 385 TRP A CG    1 
ATOM   2605 C CD1   . TRP A 1 385 ? 126.033 159.548 166.351 1.00 22.86  ? 385 TRP A CD1   1 
ATOM   2606 C CD2   . TRP A 1 385 ? 128.015 159.531 167.378 1.00 19.43  ? 385 TRP A CD2   1 
ATOM   2607 N NE1   . TRP A 1 385 ? 126.027 160.553 167.284 1.00 18.78  ? 385 TRP A NE1   1 
ATOM   2608 C CE2   . TRP A 1 385 ? 127.232 160.561 167.932 1.00 16.46  ? 385 TRP A CE2   1 
ATOM   2609 C CE3   . TRP A 1 385 ? 129.306 159.328 167.869 1.00 20.31  ? 385 TRP A CE3   1 
ATOM   2610 C CZ2   . TRP A 1 385 ? 127.696 161.383 168.951 1.00 17.06  ? 385 TRP A CZ2   1 
ATOM   2611 C CZ3   . TRP A 1 385 ? 129.764 160.146 168.878 1.00 20.01  ? 385 TRP A CZ3   1 
ATOM   2612 C CH2   . TRP A 1 385 ? 128.962 161.161 169.408 1.00 19.87  ? 385 TRP A CH2   1 
ATOM   2613 N N     . LEU A 1 386 ? 129.740 156.331 163.790 1.00 17.48  ? 386 LEU A N     1 
ATOM   2614 C CA    . LEU A 1 386 ? 130.236 155.018 163.401 1.00 14.55  ? 386 LEU A CA    1 
ATOM   2615 C C     . LEU A 1 386 ? 131.060 154.470 164.552 1.00 24.21  ? 386 LEU A C     1 
ATOM   2616 O O     . LEU A 1 386 ? 132.057 155.081 164.948 1.00 28.49  ? 386 LEU A O     1 
ATOM   2617 C CB    . LEU A 1 386 ? 131.081 155.081 162.128 1.00 15.93  ? 386 LEU A CB    1 
ATOM   2618 C CG    . LEU A 1 386 ? 131.935 153.839 161.877 1.00 13.26  ? 386 LEU A CG    1 
ATOM   2619 C CD1   . LEU A 1 386 ? 131.060 152.616 161.669 1.00 15.38  ? 386 LEU A CD1   1 
ATOM   2620 C CD2   . LEU A 1 386 ? 132.851 154.046 160.688 1.00 20.50  ? 386 LEU A CD2   1 
ATOM   2621 N N     . TYR A 1 387 ? 130.640 153.335 165.096 1.00 26.22  ? 387 TYR A N     1 
ATOM   2622 C CA    . TYR A 1 387 ? 131.376 152.656 166.151 1.00 16.18  ? 387 TYR A CA    1 
ATOM   2623 C C     . TYR A 1 387 ? 131.916 151.339 165.622 1.00 17.05  ? 387 TYR A C     1 
ATOM   2624 O O     . TYR A 1 387 ? 131.160 150.515 165.098 1.00 27.91  ? 387 TYR A O     1 
ATOM   2625 C CB    . TYR A 1 387 ? 130.498 152.432 167.377 1.00 15.79  ? 387 TYR A CB    1 
ATOM   2626 C CG    . TYR A 1 387 ? 130.370 153.670 168.218 1.00 14.38  ? 387 TYR A CG    1 
ATOM   2627 C CD1   . TYR A 1 387 ? 131.361 154.018 169.116 1.00 18.72  ? 387 TYR A CD1   1 
ATOM   2628 C CD2   . TYR A 1 387 ? 129.270 154.500 168.103 1.00 16.23  ? 387 TYR A CD2   1 
ATOM   2629 C CE1   . TYR A 1 387 ? 131.256 155.151 169.886 1.00 22.98  ? 387 TYR A CE1   1 
ATOM   2630 C CE2   . TYR A 1 387 ? 129.157 155.635 168.865 1.00 16.01  ? 387 TYR A CE2   1 
ATOM   2631 C CZ    . TYR A 1 387 ? 130.154 155.959 169.752 1.00 20.60  ? 387 TYR A CZ    1 
ATOM   2632 O OH    . TYR A 1 387 ? 130.054 157.090 170.520 1.00 22.86  ? 387 TYR A OH    1 
ATOM   2633 N N     . PHE A 1 388 ? 133.219 151.152 165.760 1.00 16.17  ? 388 PHE A N     1 
ATOM   2634 C CA    . PHE A 1 388 ? 133.911 149.969 165.275 1.00 21.59  ? 388 PHE A CA    1 
ATOM   2635 C C     . PHE A 1 388 ? 134.364 149.145 166.472 1.00 32.23  ? 388 PHE A C     1 
ATOM   2636 O O     . PHE A 1 388 ? 135.172 149.612 167.282 1.00 34.56  ? 388 PHE A O     1 
ATOM   2637 C CB    . PHE A 1 388 ? 135.100 150.360 164.401 1.00 20.66  ? 388 PHE A CB    1 
ATOM   2638 C CG    . PHE A 1 388 ? 135.898 149.198 163.904 1.00 22.81  ? 388 PHE A CG    1 
ATOM   2639 C CD1   . PHE A 1 388 ? 135.494 148.490 162.788 1.00 31.37  ? 388 PHE A CD1   1 
ATOM   2640 C CD2   . PHE A 1 388 ? 137.061 148.820 164.543 1.00 30.31  ? 388 PHE A CD2   1 
ATOM   2641 C CE1   . PHE A 1 388 ? 136.229 147.423 162.327 1.00 37.20  ? 388 PHE A CE1   1 
ATOM   2642 C CE2   . PHE A 1 388 ? 137.799 147.755 164.086 1.00 35.09  ? 388 PHE A CE2   1 
ATOM   2643 C CZ    . PHE A 1 388 ? 137.383 147.056 162.978 1.00 36.43  ? 388 PHE A CZ    1 
ATOM   2644 N N     . ASP A 1 389 ? 133.836 147.931 166.580 1.00 34.80  ? 389 ASP A N     1 
ATOM   2645 C CA    . ASP A 1 389 ? 134.175 147.002 167.648 1.00 29.25  ? 389 ASP A CA    1 
ATOM   2646 C C     . ASP A 1 389 ? 135.206 146.003 167.137 1.00 32.85  ? 389 ASP A C     1 
ATOM   2647 O O     . ASP A 1 389 ? 134.968 145.315 166.139 1.00 39.15  ? 389 ASP A O     1 
ATOM   2648 C CB    . ASP A 1 389 ? 132.919 146.277 168.133 1.00 37.08  ? 389 ASP A CB    1 
ATOM   2649 C CG    . ASP A 1 389 ? 133.225 145.173 169.117 1.00 47.12  ? 389 ASP A CG    1 
ATOM   2650 O OD1   . ASP A 1 389 ? 134.214 145.308 169.859 1.00 47.30  ? 389 ASP A OD1   1 
ATOM   2651 O OD2   . ASP A 1 389 ? 132.488 144.164 169.140 1.00 47.58  ? 389 ASP A OD2   1 
ATOM   2652 N N     . ALA A 1 390 ? 136.349 145.930 167.820 1.00 30.78  ? 390 ALA A N     1 
ATOM   2653 C CA    . ALA A 1 390 ? 137.399 144.970 167.497 1.00 34.33  ? 390 ALA A CA    1 
ATOM   2654 C C     . ALA A 1 390 ? 137.806 144.160 168.721 1.00 38.42  ? 390 ALA A C     1 
ATOM   2655 O O     . ALA A 1 390 ? 138.925 143.642 168.774 1.00 39.63  ? 390 ALA A O     1 
ATOM   2656 C CB    . ALA A 1 390 ? 138.622 145.667 166.898 1.00 30.65  ? 390 ALA A CB    1 
ATOM   2657 N N     . LEU A 1 391 ? 136.919 144.052 169.710 1.00 36.61  ? 391 LEU A N     1 
ATOM   2658 C CA    . LEU A 1 391 ? 137.228 143.339 170.940 1.00 31.61  ? 391 LEU A CA    1 
ATOM   2659 C C     . LEU A 1 391 ? 137.404 141.845 170.723 1.00 32.90  ? 391 LEU A C     1 
ATOM   2660 O O     . LEU A 1 391 ? 137.855 141.153 171.643 1.00 40.18  ? 391 LEU A O     1 
ATOM   2661 C CB    . LEU A 1 391 ? 136.134 143.597 171.974 1.00 30.17  ? 391 LEU A CB    1 
ATOM   2662 C CG    . LEU A 1 391 ? 135.972 145.052 172.415 1.00 31.89  ? 391 LEU A CG    1 
ATOM   2663 C CD1   . LEU A 1 391 ? 134.686 145.226 173.194 1.00 32.20  ? 391 LEU A CD1   1 
ATOM   2664 C CD2   . LEU A 1 391 ? 137.168 145.502 173.242 1.00 35.01  ? 391 LEU A CD2   1 
ATOM   2665 N N     . ASP A 1 392 ? 137.045 141.331 169.543 1.00 32.10  ? 392 ASP A N     1 
ATOM   2666 C CA    . ASP A 1 392 ? 137.303 139.932 169.221 1.00 33.16  ? 392 ASP A CA    1 
ATOM   2667 C C     . ASP A 1 392 ? 138.784 139.593 169.323 1.00 30.74  ? 392 ASP A C     1 
ATOM   2668 O O     . ASP A 1 392 ? 139.142 138.433 169.554 1.00 36.68  ? 392 ASP A O     1 
ATOM   2669 C CB    . ASP A 1 392 ? 136.775 139.599 167.821 1.00 33.50  ? 392 ASP A CB    1 
ATOM   2670 C CG    . ASP A 1 392 ? 137.073 140.685 166.802 1.00 37.11  ? 392 ASP A CG    1 
ATOM   2671 O OD1   . ASP A 1 392 ? 136.438 141.759 166.863 1.00 41.00  ? 392 ASP A OD1   1 
ATOM   2672 O OD2   . ASP A 1 392 ? 137.945 140.464 165.936 1.00 35.21  ? 392 ASP A OD2   1 
ATOM   2673 N N     . CYS A 1 393 ? 139.657 140.587 169.153 1.00 27.29  ? 393 CYS A N     1 
ATOM   2674 C CA    . CYS A 1 393 ? 141.090 140.357 169.268 1.00 29.54  ? 393 CYS A CA    1 
ATOM   2675 C C     . CYS A 1 393 ? 141.512 139.997 170.686 1.00 32.04  ? 393 CYS A C     1 
ATOM   2676 O O     . CYS A 1 393 ? 142.625 139.499 170.879 1.00 38.83  ? 393 CYS A O     1 
ATOM   2677 C CB    . CYS A 1 393 ? 141.852 141.594 168.792 1.00 35.38  ? 393 CYS A CB    1 
ATOM   2678 S SG    . CYS A 1 393 ? 141.467 142.079 167.098 1.00 50.02  ? 393 CYS A SG    1 
ATOM   2679 N N     . LEU A 1 394 ? 140.656 140.239 171.675 1.00 31.79  ? 394 LEU A N     1 
ATOM   2680 C CA    . LEU A 1 394 ? 140.975 139.924 173.055 1.00 34.47  ? 394 LEU A CA    1 
ATOM   2681 C C     . LEU A 1 394 ? 140.945 138.416 173.297 1.00 38.92  ? 394 LEU A C     1 
ATOM   2682 O O     . LEU A 1 394 ? 140.319 137.666 172.544 1.00 42.21  ? 394 LEU A O     1 
ATOM   2683 C CB    . LEU A 1 394 ? 139.993 140.616 173.994 1.00 34.23  ? 394 LEU A CB    1 
ATOM   2684 C CG    . LEU A 1 394 ? 140.140 142.128 174.096 1.00 29.33  ? 394 LEU A CG    1 
ATOM   2685 C CD1   . LEU A 1 394 ? 139.207 142.655 175.160 1.00 21.94  ? 394 LEU A CD1   1 
ATOM   2686 C CD2   . LEU A 1 394 ? 141.583 142.482 174.412 1.00 34.80  ? 394 LEU A CD2   1 
ATOM   2687 N N     . PRO A 1 395 ? 141.623 137.950 174.346 1.00 38.10  ? 395 PRO A N     1 
ATOM   2688 C CA    . PRO A 1 395 ? 141.551 136.530 174.702 1.00 45.83  ? 395 PRO A CA    1 
ATOM   2689 C C     . PRO A 1 395 ? 140.133 136.112 175.064 1.00 52.47  ? 395 PRO A C     1 
ATOM   2690 O O     . PRO A 1 395 ? 139.289 136.925 175.447 1.00 47.67  ? 395 PRO A O     1 
ATOM   2691 C CB    . PRO A 1 395 ? 142.492 136.417 175.906 1.00 47.58  ? 395 PRO A CB    1 
ATOM   2692 C CG    . PRO A 1 395 ? 143.441 137.543 175.739 1.00 40.91  ? 395 PRO A CG    1 
ATOM   2693 C CD    . PRO A 1 395 ? 142.640 138.660 175.140 1.00 37.58  ? 395 PRO A CD    1 
ATOM   2694 N N     . GLU A 1 396 ? 139.882 134.813 174.929 1.00 56.94  ? 396 GLU A N     1 
ATOM   2695 C CA    . GLU A 1 396 ? 138.554 134.255 175.121 1.00 56.44  ? 396 GLU A CA    1 
ATOM   2696 C C     . GLU A 1 396 ? 138.102 134.405 176.573 1.00 63.02  ? 396 GLU A C     1 
ATOM   2697 O O     . GLU A 1 396 ? 138.869 134.784 177.463 1.00 68.97  ? 396 GLU A O     1 
ATOM   2698 C CB    . GLU A 1 396 ? 138.528 132.783 174.711 1.00 55.85  ? 396 GLU A CB    1 
ATOM   2699 C CG    . GLU A 1 396 ? 138.723 132.534 173.222 1.00 56.95  ? 396 GLU A CG    1 
ATOM   2700 C CD    . GLU A 1 396 ? 140.161 132.228 172.858 1.00 52.92  ? 396 GLU A CD    1 
ATOM   2701 O OE1   . GLU A 1 396 ? 141.038 133.079 173.108 1.00 50.02  ? 396 GLU A OE1   1 
ATOM   2702 O OE2   . GLU A 1 396 ? 140.417 131.129 172.323 1.00 48.58  ? 396 GLU A OE2   1 
ATOM   2703 N N     . ASP A 1 397 ? 136.822 134.100 176.801 1.00 65.46  ? 397 ASP A N     1 
ATOM   2704 C CA    . ASP A 1 397 ? 136.244 134.248 178.134 1.00 71.65  ? 397 ASP A CA    1 
ATOM   2705 C C     . ASP A 1 397 ? 136.908 133.314 179.138 1.00 68.25  ? 397 ASP A C     1 
ATOM   2706 O O     . ASP A 1 397 ? 137.205 133.717 180.269 1.00 66.24  ? 397 ASP A O     1 
ATOM   2707 C CB    . ASP A 1 397 ? 134.738 133.996 178.081 1.00 79.80  ? 397 ASP A CB    1 
ATOM   2708 C CG    . ASP A 1 397 ? 134.023 134.933 177.128 1.00 86.15  ? 397 ASP A CG    1 
ATOM   2709 O OD1   . ASP A 1 397 ? 134.520 136.059 176.914 1.00 80.66  ? 397 ASP A OD1   1 
ATOM   2710 O OD2   . ASP A 1 397 ? 132.964 134.544 176.591 1.00 93.69  ? 397 ASP A OD2   1 
ATOM   2711 N N     . GLY A 1 398 ? 137.148 132.064 178.747 1.00 68.07  ? 398 GLY A N     1 
ATOM   2712 C CA    . GLY A 1 398 ? 137.791 131.116 179.637 1.00 73.75  ? 398 GLY A CA    1 
ATOM   2713 C C     . GLY A 1 398 ? 139.292 131.257 179.754 1.00 72.56  ? 398 GLY A C     1 
ATOM   2714 O O     . GLY A 1 398 ? 139.896 130.624 180.625 1.00 76.79  ? 398 GLY A O     1 
ATOM   2715 N N     . ASP A 1 399 ? 139.904 132.070 178.904 1.00 65.87  ? 399 ASP A N     1 
ATOM   2716 C CA    . ASP A 1 399 ? 141.334 132.333 178.897 1.00 63.22  ? 399 ASP A CA    1 
ATOM   2717 C C     . ASP A 1 399 ? 141.674 133.472 179.854 1.00 69.15  ? 399 ASP A C     1 
ATOM   2718 O O     . ASP A 1 399 ? 140.834 134.336 180.124 1.00 70.57  ? 399 ASP A O     1 
ATOM   2719 C CB    . ASP A 1 399 ? 141.800 132.686 177.487 1.00 65.44  ? 399 ASP A CB    1 
ATOM   2720 C CG    . ASP A 1 399 ? 141.702 131.514 176.529 1.00 68.84  ? 399 ASP A CG    1 
ATOM   2721 O OD1   . ASP A 1 399 ? 141.269 130.424 176.959 1.00 73.00  ? 399 ASP A OD1   1 
ATOM   2722 O OD2   . ASP A 1 399 ? 142.064 131.681 175.346 1.00 64.67  ? 399 ASP A OD2   1 
ATOM   2723 N N     . PRO A 1 400 ? 142.896 133.501 180.387 1.00 73.71  ? 400 PRO A N     1 
ATOM   2724 C CA    . PRO A 1 400 ? 143.258 134.559 181.341 1.00 67.61  ? 400 PRO A CA    1 
ATOM   2725 C C     . PRO A 1 400 ? 143.425 135.905 180.649 1.00 67.16  ? 400 PRO A C     1 
ATOM   2726 O O     . PRO A 1 400 ? 144.164 136.030 179.670 1.00 68.28  ? 400 PRO A O     1 
ATOM   2727 C CB    . PRO A 1 400 ? 144.582 134.063 181.933 1.00 67.93  ? 400 PRO A CB    1 
ATOM   2728 C CG    . PRO A 1 400 ? 145.159 133.196 180.866 1.00 70.55  ? 400 PRO A CG    1 
ATOM   2729 C CD    . PRO A 1 400 ? 143.986 132.524 180.208 1.00 72.95  ? 400 PRO A CD    1 
ATOM   2730 N N     . PHE A 1 401 ? 142.727 136.917 181.170 1.00 62.91  ? 401 PHE A N     1 
ATOM   2731 C CA    . PHE A 1 401 ? 142.873 138.277 180.681 1.00 51.65  ? 401 PHE A CA    1 
ATOM   2732 C C     . PHE A 1 401 ? 144.142 138.911 181.252 1.00 53.42  ? 401 PHE A C     1 
ATOM   2733 O O     . PHE A 1 401 ? 144.606 138.523 182.328 1.00 58.10  ? 401 PHE A O     1 
ATOM   2734 C CB    . PHE A 1 401 ? 141.654 139.113 181.060 1.00 49.57  ? 401 PHE A CB    1 
ATOM   2735 C CG    . PHE A 1 401 ? 141.513 139.357 182.537 1.00 57.68  ? 401 PHE A CG    1 
ATOM   2736 C CD1   . PHE A 1 401 ? 140.972 138.388 183.366 1.00 63.73  ? 401 PHE A CD1   1 
ATOM   2737 C CD2   . PHE A 1 401 ? 141.905 140.563 183.093 1.00 56.23  ? 401 PHE A CD2   1 
ATOM   2738 C CE1   . PHE A 1 401 ? 140.838 138.613 184.723 1.00 64.15  ? 401 PHE A CE1   1 
ATOM   2739 C CE2   . PHE A 1 401 ? 141.774 140.795 184.448 1.00 63.19  ? 401 PHE A CE2   1 
ATOM   2740 C CZ    . PHE A 1 401 ? 141.239 139.818 185.265 1.00 69.59  ? 401 PHE A CZ    1 
ATOM   2741 N N     . PRO A 1 402 ? 144.731 139.875 180.543 1.00 44.75  ? 402 PRO A N     1 
ATOM   2742 C CA    . PRO A 1 402 ? 145.977 140.487 181.024 1.00 42.22  ? 402 PRO A CA    1 
ATOM   2743 C C     . PRO A 1 402 ? 145.794 141.174 182.370 1.00 46.92  ? 402 PRO A C     1 
ATOM   2744 O O     . PRO A 1 402 ? 144.758 141.780 182.646 1.00 48.54  ? 402 PRO A O     1 
ATOM   2745 C CB    . PRO A 1 402 ? 146.326 141.491 179.922 1.00 36.50  ? 402 PRO A CB    1 
ATOM   2746 C CG    . PRO A 1 402 ? 145.632 140.981 178.711 1.00 35.33  ? 402 PRO A CG    1 
ATOM   2747 C CD    . PRO A 1 402 ? 144.364 140.358 179.201 1.00 41.62  ? 402 PRO A CD    1 
ATOM   2748 N N     . ASN A 1 403 ? 146.823 141.076 183.205 1.00 50.92  ? 403 ASN A N     1 
ATOM   2749 C CA    . ASN A 1 403 ? 146.800 141.620 184.552 1.00 55.13  ? 403 ASN A CA    1 
ATOM   2750 C C     . ASN A 1 403 ? 146.985 143.135 184.539 1.00 54.12  ? 403 ASN A C     1 
ATOM   2751 O O     . ASN A 1 403 ? 147.534 143.695 183.587 1.00 56.90  ? 403 ASN A O     1 
ATOM   2752 C CB    . ASN A 1 403 ? 147.890 140.965 185.394 1.00 56.71  ? 403 ASN A CB    1 
ATOM   2753 C CG    . ASN A 1 403 ? 147.569 139.526 185.745 1.00 68.98  ? 403 ASN A CG    1 
ATOM   2754 O OD1   . ASN A 1 403 ? 146.476 139.221 186.223 1.00 73.92  ? 403 ASN A OD1   1 
ATOM   2755 N ND2   . ASN A 1 403 ? 148.519 138.630 185.503 1.00 68.83  ? 403 ASN A ND2   1 
ATOM   2756 N N     . PRO A 1 404 ? 146.516 143.826 185.585 1.00 50.67  ? 404 PRO A N     1 
ATOM   2757 C CA    . PRO A 1 404 ? 146.738 145.281 185.652 1.00 46.42  ? 404 PRO A CA    1 
ATOM   2758 C C     . PRO A 1 404 ? 148.203 145.673 185.618 1.00 49.50  ? 404 PRO A C     1 
ATOM   2759 O O     . PRO A 1 404 ? 148.558 146.674 184.984 1.00 52.70  ? 404 PRO A O     1 
ATOM   2760 C CB    . PRO A 1 404 ? 146.080 145.674 186.982 1.00 51.16  ? 404 PRO A CB    1 
ATOM   2761 C CG    . PRO A 1 404 ? 145.105 144.587 187.269 1.00 56.43  ? 404 PRO A CG    1 
ATOM   2762 C CD    . PRO A 1 404 ? 145.692 143.335 186.702 1.00 55.91  ? 404 PRO A CD    1 
ATOM   2763 N N     . GLU A 1 405 ? 149.069 144.911 186.283 1.00 49.74  ? 405 GLU A N     1 
ATOM   2764 C CA    . GLU A 1 405 ? 150.499 145.183 186.251 1.00 54.89  ? 405 GLU A CA    1 
ATOM   2765 C C     . GLU A 1 405 ? 151.189 144.561 185.046 1.00 48.92  ? 405 GLU A C     1 
ATOM   2766 O O     . GLU A 1 405 ? 152.359 144.868 184.794 1.00 48.72  ? 405 GLU A O     1 
ATOM   2767 C CB    . GLU A 1 405 ? 151.165 144.686 187.538 1.00 60.60  ? 405 GLU A CB    1 
ATOM   2768 C CG    . GLU A 1 405 ? 150.962 145.596 188.743 1.00 62.77  ? 405 GLU A CG    1 
ATOM   2769 C CD    . GLU A 1 405 ? 149.538 145.579 189.267 1.00 65.83  ? 405 GLU A CD    1 
ATOM   2770 O OE1   . GLU A 1 405 ? 148.868 144.532 189.141 1.00 65.93  ? 405 GLU A OE1   1 
ATOM   2771 O OE2   . GLU A 1 405 ? 149.089 146.613 189.803 1.00 67.95  ? 405 GLU A OE2   1 
ATOM   2772 N N     . ASP A 1 406 ? 150.501 143.690 184.309 1.00 46.39  ? 406 ASP A N     1 
ATOM   2773 C CA    . ASP A 1 406 ? 151.064 143.150 183.080 1.00 48.10  ? 406 ASP A CA    1 
ATOM   2774 C C     . ASP A 1 406 ? 151.118 144.207 181.986 1.00 51.68  ? 406 ASP A C     1 
ATOM   2775 O O     . ASP A 1 406 ? 152.002 144.165 181.124 1.00 55.15  ? 406 ASP A O     1 
ATOM   2776 C CB    . ASP A 1 406 ? 150.243 141.945 182.620 1.00 50.99  ? 406 ASP A CB    1 
ATOM   2777 C CG    . ASP A 1 406 ? 150.902 141.184 181.484 1.00 52.13  ? 406 ASP A CG    1 
ATOM   2778 O OD1   . ASP A 1 406 ? 152.115 141.377 181.257 1.00 49.14  ? 406 ASP A OD1   1 
ATOM   2779 O OD2   . ASP A 1 406 ? 150.204 140.392 180.817 1.00 50.15  ? 406 ASP A OD2   1 
ATOM   2780 N N     . CYS A 1 407 ? 150.189 145.160 182.011 1.00 49.86  ? 407 CYS A N     1 
ATOM   2781 C CA    . CYS A 1 407 ? 150.052 146.166 180.969 1.00 41.26  ? 407 CYS A CA    1 
ATOM   2782 C C     . CYS A 1 407 ? 150.593 147.529 181.381 1.00 47.81  ? 407 CYS A C     1 
ATOM   2783 O O     . CYS A 1 407 ? 150.337 148.519 180.689 1.00 44.43  ? 407 CYS A O     1 
ATOM   2784 C CB    . CYS A 1 407 ? 148.585 146.286 180.562 1.00 36.07  ? 407 CYS A CB    1 
ATOM   2785 S SG    . CYS A 1 407 ? 147.857 144.722 180.049 1.00 41.28  ? 407 CYS A SG    1 
ATOM   2786 N N     . ALA A 1 408 ? 151.323 147.605 182.490 1.00 54.76  ? 408 ALA A N     1 
ATOM   2787 C CA    . ALA A 1 408 ? 151.870 148.879 182.930 1.00 52.58  ? 408 ALA A CA    1 
ATOM   2788 C C     . ALA A 1 408 ? 152.909 149.382 181.929 1.00 48.30  ? 408 ALA A C     1 
ATOM   2789 O O     . ALA A 1 408 ? 153.624 148.580 181.322 1.00 48.64  ? 408 ALA A O     1 
ATOM   2790 C CB    . ALA A 1 408 ? 152.501 148.743 184.315 1.00 52.11  ? 408 ALA A CB    1 
ATOM   2791 N N     . PRO A 1 409 ? 152.998 150.696 181.720 1.00 45.42  ? 409 PRO A N     1 
ATOM   2792 C CA    . PRO A 1 409 ? 153.991 151.229 180.779 1.00 40.15  ? 409 PRO A CA    1 
ATOM   2793 C C     . PRO A 1 409 ? 155.411 150.896 181.212 1.00 37.64  ? 409 PRO A C     1 
ATOM   2794 O O     . PRO A 1 409 ? 155.736 150.899 182.400 1.00 41.34  ? 409 PRO A O     1 
ATOM   2795 C CB    . PRO A 1 409 ? 153.733 152.739 180.810 1.00 41.33  ? 409 PRO A CB    1 
ATOM   2796 C CG    . PRO A 1 409 ? 152.322 152.872 181.281 1.00 45.93  ? 409 PRO A CG    1 
ATOM   2797 C CD    . PRO A 1 409 ? 152.118 151.750 182.249 1.00 47.79  ? 409 PRO A CD    1 
ATOM   2798 N N     . ARG A 1 410 ? 156.263 150.611 180.225 1.00 37.03  ? 410 ARG A N     1 
ATOM   2799 C CA    . ARG A 1 410 ? 157.628 150.167 180.483 1.00 43.49  ? 410 ARG A CA    1 
ATOM   2800 C C     . ARG A 1 410 ? 158.663 151.016 179.753 1.00 48.21  ? 410 ARG A C     1 
ATOM   2801 O O     . ARG A 1 410 ? 159.813 150.587 179.614 1.00 55.18  ? 410 ARG A O     1 
ATOM   2802 C CB    . ARG A 1 410 ? 157.796 148.696 180.094 1.00 46.30  ? 410 ARG A CB    1 
ATOM   2803 C CG    . ARG A 1 410 ? 156.942 147.732 180.900 1.00 59.64  ? 410 ARG A CG    1 
ATOM   2804 C CD    . ARG A 1 410 ? 156.928 146.338 180.285 1.00 68.45  ? 410 ARG A CD    1 
ATOM   2805 N NE    . ARG A 1 410 ? 158.265 145.779 180.123 1.00 78.86  ? 410 ARG A NE    1 
ATOM   2806 C CZ    . ARG A 1 410 ? 158.906 145.691 178.965 1.00 80.50  ? 410 ARG A CZ    1 
ATOM   2807 N NH1   . ARG A 1 410 ? 158.357 146.115 177.838 1.00 81.67  ? 410 ARG A NH1   1 
ATOM   2808 N NH2   . ARG A 1 410 ? 160.126 145.163 178.936 1.00 75.15  ? 410 ARG A NH2   1 
ATOM   2809 N N     . ARG A 1 411 ? 158.283 152.209 179.288 1.00 42.23  ? 411 ARG A N     1 
ATOM   2810 C CA    . ARG A 1 411 ? 159.168 153.082 178.517 1.00 31.88  ? 411 ARG A CA    1 
ATOM   2811 C C     . ARG A 1 411 ? 159.715 152.352 177.288 1.00 30.99  ? 411 ARG A C     1 
ATOM   2812 O O     . ARG A 1 411 ? 160.919 152.144 177.133 1.00 33.54  ? 411 ARG A O     1 
ATOM   2813 C CB    . ARG A 1 411 ? 160.306 153.626 179.388 1.00 34.70  ? 411 ARG A CB    1 
ATOM   2814 C CG    . ARG A 1 411 ? 160.138 155.077 179.804 1.00 39.49  ? 411 ARG A CG    1 
ATOM   2815 C CD    . ARG A 1 411 ? 158.893 155.276 180.648 1.00 41.85  ? 411 ARG A CD    1 
ATOM   2816 N NE    . ARG A 1 411 ? 158.927 154.481 181.869 1.00 50.65  ? 411 ARG A NE    1 
ATOM   2817 C CZ    . ARG A 1 411 ? 158.021 154.556 182.834 1.00 54.06  ? 411 ARG A CZ    1 
ATOM   2818 N NH1   . ARG A 1 411 ? 156.997 155.390 182.757 1.00 56.77  ? 411 ARG A NH1   1 
ATOM   2819 N NH2   . ARG A 1 411 ? 158.147 153.776 183.904 1.00 55.64  ? 411 ARG A NH2   1 
ATOM   2820 N N     . CYS A 1 412 ? 158.795 151.962 176.411 1.00 31.99  ? 412 CYS A N     1 
ATOM   2821 C CA    . CYS A 1 412 ? 159.132 151.230 175.201 1.00 34.90  ? 412 CYS A CA    1 
ATOM   2822 C C     . CYS A 1 412 ? 158.196 151.673 174.085 1.00 30.94  ? 412 CYS A C     1 
ATOM   2823 O O     . CYS A 1 412 ? 157.177 152.327 174.321 1.00 30.14  ? 412 CYS A O     1 
ATOM   2824 C CB    . CYS A 1 412 ? 159.045 149.714 175.423 1.00 35.55  ? 412 CYS A CB    1 
ATOM   2825 S SG    . CYS A 1 412 ? 159.895 148.708 174.187 1.00 48.28  ? 412 CYS A SG    1 
ATOM   2826 N N     . ARG A 1 413 ? 158.562 151.311 172.854 1.00 23.51  ? 413 ARG A N     1 
ATOM   2827 C CA    . ARG A 1 413 ? 157.755 151.678 171.696 1.00 19.99  ? 413 ARG A CA    1 
ATOM   2828 C C     . ARG A 1 413 ? 156.334 151.149 171.817 1.00 25.68  ? 413 ARG A C     1 
ATOM   2829 O O     . ARG A 1 413 ? 155.379 151.809 171.393 1.00 30.02  ? 413 ARG A O     1 
ATOM   2830 C CB    . ARG A 1 413 ? 158.395 151.142 170.419 1.00 19.49  ? 413 ARG A CB    1 
ATOM   2831 C CG    . ARG A 1 413 ? 159.718 151.763 170.054 1.00 21.31  ? 413 ARG A CG    1 
ATOM   2832 C CD    . ARG A 1 413 ? 160.278 151.073 168.831 1.00 19.90  ? 413 ARG A CD    1 
ATOM   2833 N NE    . ARG A 1 413 ? 159.238 150.843 167.836 1.00 15.99  ? 413 ARG A NE    1 
ATOM   2834 C CZ    . ARG A 1 413 ? 159.121 151.513 166.700 1.00 16.18  ? 413 ARG A CZ    1 
ATOM   2835 N NH1   . ARG A 1 413 ? 159.984 152.455 166.361 1.00 16.99  ? 413 ARG A NH1   1 
ATOM   2836 N NH2   . ARG A 1 413 ? 158.116 151.226 165.879 1.00 18.35  ? 413 ARG A NH2   1 
ATOM   2837 N N     . TYR A 1 414 ? 156.175 149.960 172.393 1.00 24.95  ? 414 TYR A N     1 
ATOM   2838 C CA    . TYR A 1 414 ? 154.917 149.232 172.360 1.00 21.26  ? 414 TYR A CA    1 
ATOM   2839 C C     . TYR A 1 414 ? 154.070 149.460 173.604 1.00 22.41  ? 414 TYR A C     1 
ATOM   2840 O O     . TYR A 1 414 ? 153.185 148.652 173.897 1.00 28.64  ? 414 TYR A O     1 
ATOM   2841 C CB    . TYR A 1 414 ? 155.194 147.745 172.163 1.00 20.80  ? 414 TYR A CB    1 
ATOM   2842 C CG    . TYR A 1 414 ? 156.269 147.489 171.140 1.00 20.10  ? 414 TYR A CG    1 
ATOM   2843 C CD1   . TYR A 1 414 ? 156.017 147.652 169.790 1.00 20.45  ? 414 TYR A CD1   1 
ATOM   2844 C CD2   . TYR A 1 414 ? 157.540 147.095 171.524 1.00 18.26  ? 414 TYR A CD2   1 
ATOM   2845 C CE1   . TYR A 1 414 ? 156.995 147.427 168.855 1.00 22.05  ? 414 TYR A CE1   1 
ATOM   2846 C CE2   . TYR A 1 414 ? 158.524 146.870 170.595 1.00 18.23  ? 414 TYR A CE2   1 
ATOM   2847 C CZ    . TYR A 1 414 ? 158.245 147.035 169.260 1.00 22.37  ? 414 TYR A CZ    1 
ATOM   2848 O OH    . TYR A 1 414 ? 159.225 146.807 168.323 1.00 31.06  ? 414 TYR A OH    1 
ATOM   2849 N N     . ASP A 1 415 ? 154.316 150.549 174.335 1.00 23.75  ? 415 ASP A N     1 
ATOM   2850 C CA    . ASP A 1 415 ? 153.509 150.842 175.514 1.00 24.65  ? 415 ASP A CA    1 
ATOM   2851 C C     . ASP A 1 415 ? 152.051 151.077 175.150 1.00 23.11  ? 415 ASP A C     1 
ATOM   2852 O O     . ASP A 1 415 ? 151.162 150.844 175.976 1.00 26.80  ? 415 ASP A O     1 
ATOM   2853 C CB    . ASP A 1 415 ? 154.076 152.051 176.253 1.00 31.74  ? 415 ASP A CB    1 
ATOM   2854 C CG    . ASP A 1 415 ? 155.413 151.762 176.899 1.00 38.11  ? 415 ASP A CG    1 
ATOM   2855 O OD1   . ASP A 1 415 ? 155.698 150.578 177.173 1.00 43.04  ? 415 ASP A OD1   1 
ATOM   2856 O OD2   . ASP A 1 415 ? 156.175 152.718 177.140 1.00 31.64  ? 415 ASP A OD2   1 
ATOM   2857 N N     . GLY A 1 416 ? 151.785 151.546 173.934 1.00 25.23  ? 416 GLY A N     1 
ATOM   2858 C CA    . GLY A 1 416 ? 150.417 151.687 173.482 1.00 27.91  ? 416 GLY A CA    1 
ATOM   2859 C C     . GLY A 1 416 ? 149.762 150.401 173.048 1.00 28.19  ? 416 GLY A C     1 
ATOM   2860 O O     . GLY A 1 416 ? 148.541 150.362 172.883 1.00 31.72  ? 416 GLY A O     1 
ATOM   2861 N N     . GLN A 1 417 ? 150.549 149.343 172.871 1.00 28.55  ? 417 GLN A N     1 
ATOM   2862 C CA    . GLN A 1 417 ? 150.046 148.029 172.496 1.00 28.45  ? 417 GLN A CA    1 
ATOM   2863 C C     . GLN A 1 417 ? 149.975 147.088 173.693 1.00 30.98  ? 417 GLN A C     1 
ATOM   2864 O O     . GLN A 1 417 ? 148.935 146.470 173.941 1.00 34.36  ? 417 GLN A O     1 
ATOM   2865 C CB    . GLN A 1 417 ? 150.935 147.435 171.400 1.00 25.64  ? 417 GLN A CB    1 
ATOM   2866 C CG    . GLN A 1 417 ? 150.329 146.275 170.647 1.00 27.93  ? 417 GLN A CG    1 
ATOM   2867 C CD    . GLN A 1 417 ? 151.220 145.809 169.519 1.00 29.94  ? 417 GLN A CD    1 
ATOM   2868 O OE1   . GLN A 1 417 ? 152.268 146.397 169.259 1.00 31.54  ? 417 GLN A OE1   1 
ATOM   2869 N NE2   . GLN A 1 417 ? 150.810 144.746 168.841 1.00 31.93  ? 417 GLN A NE2   1 
ATOM   2870 N N     . THR A 1 418 ? 151.057 147.005 174.470 1.00 23.94  ? 418 THR A N     1 
ATOM   2871 C CA    . THR A 1 418 ? 151.050 146.193 175.678 1.00 20.57  ? 418 THR A CA    1 
ATOM   2872 C C     . THR A 1 418 ? 150.009 146.673 176.677 1.00 25.22  ? 418 THR A C     1 
ATOM   2873 O O     . THR A 1 418 ? 149.652 145.925 177.592 1.00 38.75  ? 418 THR A O     1 
ATOM   2874 C CB    . THR A 1 418 ? 152.430 146.199 176.336 1.00 22.54  ? 418 THR A CB    1 
ATOM   2875 O OG1   . THR A 1 418 ? 152.801 147.540 176.669 1.00 24.85  ? 418 THR A OG1   1 
ATOM   2876 C CG2   . THR A 1 418 ? 153.462 145.619 175.403 1.00 24.10  ? 418 THR A CG2   1 
ATOM   2877 N N     . ALA A 1 419 ? 149.519 147.902 176.525 1.00 20.71  ? 419 ALA A N     1 
ATOM   2878 C CA    . ALA A 1 419 ? 148.471 148.402 177.399 1.00 22.95  ? 419 ALA A CA    1 
ATOM   2879 C C     . ALA A 1 419 ? 147.153 147.665 177.206 1.00 25.83  ? 419 ALA A C     1 
ATOM   2880 O O     . ALA A 1 419 ? 146.281 147.751 178.077 1.00 27.75  ? 419 ALA A O     1 
ATOM   2881 C CB    . ALA A 1 419 ? 148.273 149.901 177.176 1.00 28.50  ? 419 ALA A CB    1 
ATOM   2882 N N     . VAL A 1 420 ? 146.978 146.946 176.094 1.00 29.06  ? 420 VAL A N     1 
ATOM   2883 C CA    . VAL A 1 420 ? 145.780 146.152 175.865 1.00 28.18  ? 420 VAL A CA    1 
ATOM   2884 C C     . VAL A 1 420 ? 146.093 144.664 175.761 1.00 30.51  ? 420 VAL A C     1 
ATOM   2885 O O     . VAL A 1 420 ? 145.340 143.830 176.276 1.00 32.96  ? 420 VAL A O     1 
ATOM   2886 C CB    . VAL A 1 420 ? 145.004 146.639 174.617 1.00 28.31  ? 420 VAL A CB    1 
ATOM   2887 C CG1   . VAL A 1 420 ? 145.926 146.829 173.436 1.00 26.65  ? 420 VAL A CG1   1 
ATOM   2888 C CG2   . VAL A 1 420 ? 143.882 145.677 174.266 1.00 32.04  ? 420 VAL A CG2   1 
ATOM   2889 N N     . PHE A 1 421 ? 147.206 144.303 175.121 1.00 31.04  ? 421 PHE A N     1 
ATOM   2890 C CA    . PHE A 1 421 ? 147.513 142.901 174.871 1.00 27.31  ? 421 PHE A CA    1 
ATOM   2891 C C     . PHE A 1 421 ? 148.499 142.293 175.860 1.00 28.39  ? 421 PHE A C     1 
ATOM   2892 O O     . PHE A 1 421 ? 148.566 141.064 175.958 1.00 35.77  ? 421 PHE A O     1 
ATOM   2893 C CB    . PHE A 1 421 ? 148.055 142.724 173.448 1.00 28.31  ? 421 PHE A CB    1 
ATOM   2894 C CG    . PHE A 1 421 ? 147.042 143.001 172.374 1.00 29.37  ? 421 PHE A CG    1 
ATOM   2895 C CD1   . PHE A 1 421 ? 145.936 142.181 172.218 1.00 27.52  ? 421 PHE A CD1   1 
ATOM   2896 C CD2   . PHE A 1 421 ? 147.198 144.072 171.514 1.00 31.67  ? 421 PHE A CD2   1 
ATOM   2897 C CE1   . PHE A 1 421 ? 145.005 142.431 171.235 1.00 30.32  ? 421 PHE A CE1   1 
ATOM   2898 C CE2   . PHE A 1 421 ? 146.270 144.327 170.528 1.00 35.77  ? 421 PHE A CE2   1 
ATOM   2899 C CZ    . PHE A 1 421 ? 145.172 143.504 170.388 1.00 36.41  ? 421 PHE A CZ    1 
ATOM   2900 N N     . GLY A 1 422 ? 149.264 143.103 176.586 1.00 25.14  ? 422 GLY A N     1 
ATOM   2901 C CA    . GLY A 1 422 ? 150.244 142.573 177.511 1.00 23.53  ? 422 GLY A CA    1 
ATOM   2902 C C     . GLY A 1 422 ? 151.627 142.446 176.905 1.00 24.56  ? 422 GLY A C     1 
ATOM   2903 O O     . GLY A 1 422 ? 151.863 142.695 175.721 1.00 27.92  ? 422 GLY A O     1 
ATOM   2904 N N     . THR A 1 423 ? 152.570 142.042 177.758 1.00 28.86  ? 423 THR A N     1 
ATOM   2905 C CA    . THR A 1 423 ? 153.974 141.987 177.361 1.00 30.54  ? 423 THR A CA    1 
ATOM   2906 C C     . THR A 1 423 ? 154.330 140.661 176.699 1.00 33.05  ? 423 THR A C     1 
ATOM   2907 O O     . THR A 1 423 ? 155.110 140.633 175.738 1.00 31.91  ? 423 THR A O     1 
ATOM   2908 C CB    . THR A 1 423 ? 154.870 142.225 178.576 1.00 35.39  ? 423 THR A CB    1 
ATOM   2909 O OG1   . THR A 1 423 ? 154.443 143.408 179.260 1.00 45.12  ? 423 THR A OG1   1 
ATOM   2910 C CG2   . THR A 1 423 ? 156.317 142.395 178.144 1.00 40.24  ? 423 THR A CG2   1 
ATOM   2911 N N     . ASN A 1 424 ? 153.784 139.553 177.203 1.00 33.20  ? 424 ASN A N     1 
ATOM   2912 C CA    . ASN A 1 424 ? 154.056 138.258 176.591 1.00 32.82  ? 424 ASN A CA    1 
ATOM   2913 C C     . ASN A 1 424 ? 153.491 138.181 175.179 1.00 33.60  ? 424 ASN A C     1 
ATOM   2914 O O     . ASN A 1 424 ? 154.061 137.502 174.315 1.00 36.58  ? 424 ASN A O     1 
ATOM   2915 C CB    . ASN A 1 424 ? 153.495 137.140 177.470 1.00 35.17  ? 424 ASN A CB    1 
ATOM   2916 C CG    . ASN A 1 424 ? 152.140 137.480 178.053 1.00 39.82  ? 424 ASN A CG    1 
ATOM   2917 O OD1   . ASN A 1 424 ? 151.306 138.103 177.398 1.00 38.81  ? 424 ASN A OD1   1 
ATOM   2918 N ND2   . ASN A 1 424 ? 151.915 137.074 179.297 1.00 44.83  ? 424 ASN A ND2   1 
ATOM   2919 N N     . PHE A 1 425 ? 152.385 138.881 174.921 1.00 29.08  ? 425 PHE A N     1 
ATOM   2920 C CA    . PHE A 1 425 ? 151.876 138.981 173.560 1.00 24.12  ? 425 PHE A CA    1 
ATOM   2921 C C     . PHE A 1 425 ? 152.879 139.685 172.657 1.00 22.64  ? 425 PHE A C     1 
ATOM   2922 O O     . PHE A 1 425 ? 153.074 139.287 171.504 1.00 29.10  ? 425 PHE A O     1 
ATOM   2923 C CB    . PHE A 1 425 ? 150.534 139.709 173.558 1.00 23.40  ? 425 PHE A CB    1 
ATOM   2924 C CG    . PHE A 1 425 ? 149.791 139.611 172.260 1.00 25.89  ? 425 PHE A CG    1 
ATOM   2925 C CD1   . PHE A 1 425 ? 148.977 138.526 171.995 1.00 28.30  ? 425 PHE A CD1   1 
ATOM   2926 C CD2   . PHE A 1 425 ? 149.897 140.608 171.309 1.00 26.42  ? 425 PHE A CD2   1 
ATOM   2927 C CE1   . PHE A 1 425 ? 148.287 138.435 170.804 1.00 24.97  ? 425 PHE A CE1   1 
ATOM   2928 C CE2   . PHE A 1 425 ? 149.208 140.522 170.118 1.00 24.60  ? 425 PHE A CE2   1 
ATOM   2929 C CZ    . PHE A 1 425 ? 148.405 139.435 169.865 1.00 24.30  ? 425 PHE A CZ    1 
ATOM   2930 N N     . GLN A 1 426 ? 153.541 140.724 173.167 1.00 20.68  ? 426 GLN A N     1 
ATOM   2931 C CA    . GLN A 1 426 ? 154.586 141.378 172.388 1.00 23.08  ? 426 GLN A CA    1 
ATOM   2932 C C     . GLN A 1 426 ? 155.771 140.451 172.156 1.00 26.18  ? 426 GLN A C     1 
ATOM   2933 O O     . GLN A 1 426 ? 156.354 140.442 171.065 1.00 28.41  ? 426 GLN A O     1 
ATOM   2934 C CB    . GLN A 1 426 ? 155.038 142.663 173.079 1.00 23.69  ? 426 GLN A CB    1 
ATOM   2935 C CG    . GLN A 1 426 ? 154.404 143.911 172.503 1.00 24.49  ? 426 GLN A CG    1 
ATOM   2936 C CD    . GLN A 1 426 ? 154.631 144.038 171.016 1.00 24.37  ? 426 GLN A CD    1 
ATOM   2937 O OE1   . GLN A 1 426 ? 153.685 144.179 170.246 1.00 24.17  ? 426 GLN A OE1   1 
ATOM   2938 N NE2   . GLN A 1 426 ? 155.889 143.985 170.601 1.00 25.87  ? 426 GLN A NE2   1 
ATOM   2939 N N     . GLU A 1 427 ? 156.150 139.672 173.172 1.00 26.43  ? 427 GLU A N     1 
ATOM   2940 C CA    . GLU A 1 427 ? 157.265 138.744 173.005 1.00 24.82  ? 427 GLU A CA    1 
ATOM   2941 C C     . GLU A 1 427 ? 156.954 137.686 171.955 1.00 22.23  ? 427 GLU A C     1 
ATOM   2942 O O     . GLU A 1 427 ? 157.826 137.312 171.164 1.00 25.56  ? 427 GLU A O     1 
ATOM   2943 C CB    . GLU A 1 427 ? 157.619 138.094 174.342 1.00 31.64  ? 427 GLU A CB    1 
ATOM   2944 C CG    . GLU A 1 427 ? 158.502 138.964 175.221 1.00 45.11  ? 427 GLU A CG    1 
ATOM   2945 C CD    . GLU A 1 427 ? 159.798 139.357 174.534 1.00 56.06  ? 427 GLU A CD    1 
ATOM   2946 O OE1   . GLU A 1 427 ? 160.419 138.488 173.886 1.00 53.66  ? 427 GLU A OE1   1 
ATOM   2947 O OE2   . GLU A 1 427 ? 160.192 140.539 174.634 1.00 55.96  ? 427 GLU A OE2   1 
ATOM   2948 N N     . LYS A 1 428 ? 155.720 137.183 171.935 1.00 21.35  ? 428 LYS A N     1 
ATOM   2949 C CA    . LYS A 1 428 ? 155.356 136.209 170.912 1.00 21.85  ? 428 LYS A CA    1 
ATOM   2950 C C     . LYS A 1 428 ? 155.201 136.863 169.542 1.00 24.26  ? 428 LYS A C     1 
ATOM   2951 O O     . LYS A 1 428 ? 155.448 136.214 168.520 1.00 29.09  ? 428 LYS A O     1 
ATOM   2952 C CB    . LYS A 1 428 ? 154.081 135.465 171.313 1.00 26.82  ? 428 LYS A CB    1 
ATOM   2953 C CG    . LYS A 1 428 ? 152.791 136.225 171.108 1.00 26.20  ? 428 LYS A CG    1 
ATOM   2954 C CD    . LYS A 1 428 ? 151.674 135.626 171.946 1.00 29.44  ? 428 LYS A CD    1 
ATOM   2955 C CE    . LYS A 1 428 ? 151.555 134.129 171.722 1.00 26.93  ? 428 LYS A CE    1 
ATOM   2956 N NZ    . LYS A 1 428 ? 150.536 133.517 172.616 1.00 34.01  ? 428 LYS A NZ    1 
ATOM   2957 N N     . LEU A 1 429 ? 154.802 138.136 169.499 1.00 23.25  ? 429 LEU A N     1 
ATOM   2958 C CA    . LEU A 1 429 ? 154.756 138.860 168.232 1.00 20.53  ? 429 LEU A CA    1 
ATOM   2959 C C     . LEU A 1 429 ? 156.148 139.037 167.645 1.00 19.73  ? 429 LEU A C     1 
ATOM   2960 O O     . LEU A 1 429 ? 156.336 138.918 166.429 1.00 26.58  ? 429 LEU A O     1 
ATOM   2961 C CB    . LEU A 1 429 ? 154.093 140.221 168.428 1.00 19.59  ? 429 LEU A CB    1 
ATOM   2962 C CG    . LEU A 1 429 ? 152.602 140.348 168.142 1.00 18.18  ? 429 LEU A CG    1 
ATOM   2963 C CD1   . LEU A 1 429 ? 152.131 141.733 168.510 1.00 17.40  ? 429 LEU A CD1   1 
ATOM   2964 C CD2   . LEU A 1 429 ? 152.323 140.064 166.681 1.00 25.55  ? 429 LEU A CD2   1 
ATOM   2965 N N     . SER A 1 430 ? 157.134 139.337 168.490 1.00 17.05  ? 430 SER A N     1 
ATOM   2966 C CA    . SER A 1 430 ? 158.492 139.546 168.006 1.00 19.25  ? 430 SER A CA    1 
ATOM   2967 C C     . SER A 1 430 ? 159.085 138.287 167.391 1.00 28.91  ? 430 SER A C     1 
ATOM   2968 O O     . SER A 1 430 ? 160.043 138.380 166.616 1.00 32.67  ? 430 SER A O     1 
ATOM   2969 C CB    . SER A 1 430 ? 159.387 140.040 169.141 1.00 23.02  ? 430 SER A CB    1 
ATOM   2970 O OG    . SER A 1 430 ? 159.747 138.980 170.006 1.00 34.34  ? 430 SER A OG    1 
ATOM   2971 N N     . HIS A 1 431 ? 158.541 137.118 167.717 1.00 28.62  ? 431 HIS A N     1 
ATOM   2972 C CA    . HIS A 1 431 ? 159.030 135.850 167.200 1.00 26.54  ? 431 HIS A CA    1 
ATOM   2973 C C     . HIS A 1 431 ? 158.358 135.429 165.899 1.00 25.82  ? 431 HIS A C     1 
ATOM   2974 O O     . HIS A 1 431 ? 158.738 134.398 165.334 1.00 29.93  ? 431 HIS A O     1 
ATOM   2975 C CB    . HIS A 1 431 ? 158.839 134.753 168.252 1.00 27.57  ? 431 HIS A CB    1 
ATOM   2976 C CG    . HIS A 1 431 ? 159.627 134.969 169.505 1.00 30.33  ? 431 HIS A CG    1 
ATOM   2977 N ND1   . HIS A 1 431 ? 160.851 135.601 169.517 1.00 33.97  ? 431 HIS A ND1   1 
ATOM   2978 C CD2   . HIS A 1 431 ? 159.365 134.636 170.790 1.00 34.36  ? 431 HIS A CD2   1 
ATOM   2979 C CE1   . HIS A 1 431 ? 161.310 135.647 170.754 1.00 38.89  ? 431 HIS A CE1   1 
ATOM   2980 N NE2   . HIS A 1 431 ? 160.426 135.068 171.547 1.00 43.13  ? 431 HIS A NE2   1 
ATOM   2981 N N     . GLN A 1 432 ? 157.376 136.184 165.410 1.00 21.02  ? 432 GLN A N     1 
ATOM   2982 C CA    . GLN A 1 432 ? 156.638 135.772 164.223 1.00 21.08  ? 432 GLN A CA    1 
ATOM   2983 C C     . GLN A 1 432 ? 157.413 136.087 162.949 1.00 26.32  ? 432 GLN A C     1 
ATOM   2984 O O     . GLN A 1 432 ? 157.924 137.195 162.771 1.00 30.31  ? 432 GLN A O     1 
ATOM   2985 C CB    . GLN A 1 432 ? 155.275 136.458 164.184 1.00 24.00  ? 432 GLN A CB    1 
ATOM   2986 C CG    . GLN A 1 432 ? 154.436 136.232 165.429 1.00 26.46  ? 432 GLN A CG    1 
ATOM   2987 C CD    . GLN A 1 432 ? 153.988 134.792 165.588 1.00 27.00  ? 432 GLN A CD    1 
ATOM   2988 O OE1   . GLN A 1 432 ? 153.381 134.215 164.689 1.00 24.91  ? 432 GLN A OE1   1 
ATOM   2989 N NE2   . GLN A 1 432 ? 154.288 134.203 166.737 1.00 27.98  ? 432 GLN A NE2   1 
ATOM   2990 N N     . HIS A 1 433 ? 157.477 135.107 162.048 1.00 25.74  ? 433 HIS A N     1 
ATOM   2991 C CA    . HIS A 1 433 ? 158.126 135.252 160.747 1.00 20.93  ? 433 HIS A CA    1 
ATOM   2992 C C     . HIS A 1 433 ? 157.045 135.128 159.685 1.00 22.90  ? 433 HIS A C     1 
ATOM   2993 O O     . HIS A 1 433 ? 156.486 134.045 159.489 1.00 32.80  ? 433 HIS A O     1 
ATOM   2994 C CB    . HIS A 1 433 ? 159.215 134.201 160.551 1.00 27.69  ? 433 HIS A CB    1 
ATOM   2995 C CG    . HIS A 1 433 ? 160.153 134.503 159.425 1.00 31.21  ? 433 HIS A CG    1 
ATOM   2996 N ND1   . HIS A 1 433 ? 159.797 134.379 158.101 1.00 28.21  ? 433 HIS A ND1   1 
ATOM   2997 C CD2   . HIS A 1 433 ? 161.443 134.915 159.428 1.00 33.60  ? 433 HIS A CD2   1 
ATOM   2998 C CE1   . HIS A 1 433 ? 160.823 134.708 157.337 1.00 28.69  ? 433 HIS A CE1   1 
ATOM   2999 N NE2   . HIS A 1 433 ? 161.835 135.037 158.117 1.00 32.26  ? 433 HIS A NE2   1 
ATOM   3000 N N     . TYR A 1 434 ? 156.751 136.229 159.002 1.00 21.27  ? 434 TYR A N     1 
ATOM   3001 C CA    . TYR A 1 434 ? 155.571 136.335 158.158 1.00 22.65  ? 434 TYR A CA    1 
ATOM   3002 C C     . TYR A 1 434 ? 155.971 136.570 156.712 1.00 24.90  ? 434 TYR A C     1 
ATOM   3003 O O     . TYR A 1 434 ? 156.831 137.410 156.431 1.00 27.14  ? 434 TYR A O     1 
ATOM   3004 C CB    . TYR A 1 434 ? 154.667 137.469 158.641 1.00 23.44  ? 434 TYR A CB    1 
ATOM   3005 C CG    . TYR A 1 434 ? 153.458 136.979 159.382 1.00 23.34  ? 434 TYR A CG    1 
ATOM   3006 C CD1   . TYR A 1 434 ? 153.582 136.373 160.623 1.00 25.20  ? 434 TYR A CD1   1 
ATOM   3007 C CD2   . TYR A 1 434 ? 152.190 137.112 158.840 1.00 27.29  ? 434 TYR A CD2   1 
ATOM   3008 C CE1   . TYR A 1 434 ? 152.478 135.918 161.303 1.00 29.36  ? 434 TYR A CE1   1 
ATOM   3009 C CE2   . TYR A 1 434 ? 151.081 136.659 159.510 1.00 29.93  ? 434 TYR A CE2   1 
ATOM   3010 C CZ    . TYR A 1 434 ? 151.232 136.059 160.740 1.00 32.90  ? 434 TYR A CZ    1 
ATOM   3011 O OH    . TYR A 1 434 ? 150.126 135.608 161.412 1.00 34.27  ? 434 TYR A OH    1 
ATOM   3012 N N     . LEU A 1 435 ? 155.353 135.824 155.799 1.00 25.72  ? 435 LEU A N     1 
ATOM   3013 C CA    . LEU A 1 435 ? 155.528 136.086 154.378 1.00 25.35  ? 435 LEU A CA    1 
ATOM   3014 C C     . LEU A 1 435 ? 154.481 137.090 153.920 1.00 27.71  ? 435 LEU A C     1 
ATOM   3015 O O     . LEU A 1 435 ? 153.287 136.783 153.901 1.00 32.26  ? 435 LEU A O     1 
ATOM   3016 C CB    . LEU A 1 435 ? 155.417 134.797 153.569 1.00 25.79  ? 435 LEU A CB    1 
ATOM   3017 C CG    . LEU A 1 435 ? 155.370 134.966 152.049 1.00 26.37  ? 435 LEU A CG    1 
ATOM   3018 C CD1   . LEU A 1 435 ? 156.693 135.487 151.516 1.00 31.34  ? 435 LEU A CD1   1 
ATOM   3019 C CD2   . LEU A 1 435 ? 155.009 133.657 151.385 1.00 25.56  ? 435 LEU A CD2   1 
ATOM   3020 N N     . LEU A 1 436 ? 154.924 138.279 153.535 1.00 29.06  ? 436 LEU A N     1 
ATOM   3021 C CA    . LEU A 1 436 ? 154.060 139.261 152.899 1.00 31.59  ? 436 LEU A CA    1 
ATOM   3022 C C     . LEU A 1 436 ? 154.285 139.180 151.398 1.00 35.63  ? 436 LEU A C     1 
ATOM   3023 O O     . LEU A 1 436 ? 155.404 139.405 150.922 1.00 38.64  ? 436 LEU A O     1 
ATOM   3024 C CB    . LEU A 1 436 ? 154.343 140.671 153.412 1.00 38.20  ? 436 LEU A CB    1 
ATOM   3025 C CG    . LEU A 1 436 ? 153.604 141.784 152.669 1.00 43.28  ? 436 LEU A CG    1 
ATOM   3026 C CD1   . LEU A 1 436 ? 152.120 141.758 152.989 1.00 40.32  ? 436 LEU A CD1   1 
ATOM   3027 C CD2   . LEU A 1 436 ? 154.197 143.142 152.990 1.00 43.30  ? 436 LEU A CD2   1 
ATOM   3028 N N     . VAL A 1 437 ? 153.229 138.864 150.658 1.00 41.98  ? 437 VAL A N     1 
ATOM   3029 C CA    . VAL A 1 437 ? 153.310 138.693 149.214 1.00 47.11  ? 437 VAL A CA    1 
ATOM   3030 C C     . VAL A 1 437 ? 152.627 139.893 148.574 1.00 46.68  ? 437 VAL A C     1 
ATOM   3031 O O     . VAL A 1 437 ? 151.452 140.176 148.844 1.00 43.31  ? 437 VAL A O     1 
ATOM   3032 C CB    . VAL A 1 437 ? 152.691 137.360 148.758 1.00 48.26  ? 437 VAL A CB    1 
ATOM   3033 C CG1   . VAL A 1 437 ? 151.316 137.153 149.367 1.00 47.19  ? 437 VAL A CG1   1 
ATOM   3034 C CG2   . VAL A 1 437 ? 152.639 137.281 147.241 1.00 51.09  ? 437 VAL A CG2   1 
ATOM   3035 N N     . GLY A 1 438 ? 153.381 140.616 147.754 1.00 48.88  ? 438 GLY A N     1 
ATOM   3036 C CA    . GLY A 1 438 ? 152.942 141.883 147.219 1.00 48.68  ? 438 GLY A CA    1 
ATOM   3037 C C     . GLY A 1 438 ? 153.393 143.046 148.078 1.00 44.56  ? 438 GLY A C     1 
ATOM   3038 O O     . GLY A 1 438 ? 152.962 143.184 149.227 1.00 45.54  ? 438 GLY A O     1 
ATOM   3039 N N     . ALA A 1 439 ? 154.260 143.892 147.524 1.00 43.69  ? 439 ALA A N     1 
ATOM   3040 C CA    . ALA A 1 439 ? 154.725 145.108 148.176 1.00 39.71  ? 439 ALA A CA    1 
ATOM   3041 C C     . ALA A 1 439 ? 153.962 146.340 147.708 1.00 42.19  ? 439 ALA A C     1 
ATOM   3042 O O     . ALA A 1 439 ? 154.500 147.451 147.751 1.00 47.22  ? 439 ALA A O     1 
ATOM   3043 C CB    . ALA A 1 439 ? 156.223 145.295 147.942 1.00 39.50  ? 439 ALA A CB    1 
ATOM   3044 N N     . GLY A 1 440 ? 152.723 146.166 147.265 1.00 42.75  ? 440 GLY A N     1 
ATOM   3045 C CA    . GLY A 1 440 ? 151.924 147.261 146.762 1.00 40.94  ? 440 GLY A CA    1 
ATOM   3046 C C     . GLY A 1 440 ? 151.420 148.164 147.867 1.00 36.70  ? 440 GLY A C     1 
ATOM   3047 O O     . GLY A 1 440 ? 151.981 148.228 148.962 1.00 42.77  ? 440 GLY A O     1 
ATOM   3048 N N     . ALA A 1 441 ? 150.342 148.886 147.561 1.00 34.66  ? 441 ALA A N     1 
ATOM   3049 C CA    . ALA A 1 441 ? 149.806 149.857 148.509 1.00 37.64  ? 441 ALA A CA    1 
ATOM   3050 C C     . ALA A 1 441 ? 149.354 149.182 149.799 1.00 42.36  ? 441 ALA A C     1 
ATOM   3051 O O     . ALA A 1 441 ? 149.745 149.588 150.903 1.00 50.06  ? 441 ALA A O     1 
ATOM   3052 C CB    . ALA A 1 441 ? 148.656 150.630 147.864 1.00 45.09  ? 441 ALA A CB    1 
ATOM   3053 N N     . VAL A 1 442 ? 148.536 148.135 149.677 1.00 39.56  ? 442 VAL A N     1 
ATOM   3054 C CA    . VAL A 1 442 ? 148.111 147.389 150.856 1.00 33.88  ? 442 VAL A CA    1 
ATOM   3055 C C     . VAL A 1 442 ? 149.309 146.751 151.537 1.00 33.59  ? 442 VAL A C     1 
ATOM   3056 O O     . VAL A 1 442 ? 149.386 146.703 152.768 1.00 36.22  ? 442 VAL A O     1 
ATOM   3057 C CB    . VAL A 1 442 ? 147.056 146.337 150.477 1.00 35.56  ? 442 VAL A CB    1 
ATOM   3058 C CG1   . VAL A 1 442 ? 146.607 145.606 151.715 1.00 35.07  ? 442 VAL A CG1   1 
ATOM   3059 C CG2   . VAL A 1 442 ? 145.882 146.992 149.780 1.00 42.23  ? 442 VAL A CG2   1 
ATOM   3060 N N     . GLY A 1 443 ? 150.253 146.233 150.750 1.00 34.60  ? 443 GLY A N     1 
ATOM   3061 C CA    . GLY A 1 443 ? 151.454 145.658 151.328 1.00 34.98  ? 443 GLY A CA    1 
ATOM   3062 C C     . GLY A 1 443 ? 152.287 146.658 152.104 1.00 36.82  ? 443 GLY A C     1 
ATOM   3063 O O     . GLY A 1 443 ? 152.840 146.328 153.153 1.00 43.28  ? 443 GLY A O     1 
ATOM   3064 N N     . CYS A 1 444 ? 152.374 147.895 151.615 1.00 33.56  ? 444 CYS A N     1 
ATOM   3065 C CA    . CYS A 1 444 ? 153.125 148.926 152.323 1.00 36.40  ? 444 CYS A CA    1 
ATOM   3066 C C     . CYS A 1 444 ? 152.411 149.361 153.596 1.00 39.12  ? 444 CYS A C     1 
ATOM   3067 O O     . CYS A 1 444 ? 153.056 149.618 154.621 1.00 45.85  ? 444 CYS A O     1 
ATOM   3068 C CB    . CYS A 1 444 ? 153.361 150.120 151.406 1.00 43.60  ? 444 CYS A CB    1 
ATOM   3069 S SG    . CYS A 1 444 ? 154.435 149.770 150.006 1.00 59.96  ? 444 CYS A SG    1 
ATOM   3070 N N     . GLU A 1 445 ? 151.080 149.462 153.554 1.00 33.90  ? 445 GLU A N     1 
ATOM   3071 C CA    . GLU A 1 445 ? 150.347 149.762 154.780 1.00 34.64  ? 445 GLU A CA    1 
ATOM   3072 C C     . GLU A 1 445 ? 150.459 148.619 155.788 1.00 35.75  ? 445 GLU A C     1 
ATOM   3073 O O     . GLU A 1 445 ? 150.574 148.860 156.998 1.00 36.09  ? 445 GLU A O     1 
ATOM   3074 C CB    . GLU A 1 445 ? 148.890 150.071 154.444 1.00 31.85  ? 445 GLU A CB    1 
ATOM   3075 C CG    . GLU A 1 445 ? 148.703 151.274 153.527 1.00 39.94  ? 445 GLU A CG    1 
ATOM   3076 C CD    . GLU A 1 445 ? 148.698 152.594 154.270 1.00 51.86  ? 445 GLU A CD    1 
ATOM   3077 O OE1   . GLU A 1 445 ? 148.899 152.587 155.502 1.00 54.88  ? 445 GLU A OE1   1 
ATOM   3078 O OE2   . GLU A 1 445 ? 148.477 153.640 153.624 1.00 50.37  ? 445 GLU A OE2   1 
ATOM   3079 N N     . LEU A 1 446 ? 150.490 147.377 155.302 1.00 35.43  ? 446 LEU A N     1 
ATOM   3080 C CA    . LEU A 1 446 ? 150.741 146.227 156.164 1.00 30.46  ? 446 LEU A CA    1 
ATOM   3081 C C     . LEU A 1 446 ? 152.141 146.275 156.757 1.00 29.93  ? 446 LEU A C     1 
ATOM   3082 O O     . LEU A 1 446 ? 152.347 145.884 157.906 1.00 34.45  ? 446 LEU A O     1 
ATOM   3083 C CB    . LEU A 1 446 ? 150.540 144.933 155.379 1.00 32.09  ? 446 LEU A CB    1 
ATOM   3084 C CG    . LEU A 1 446 ? 149.086 144.532 155.166 1.00 30.96  ? 446 LEU A CG    1 
ATOM   3085 C CD1   . LEU A 1 446 ? 149.004 143.244 154.371 1.00 38.21  ? 446 LEU A CD1   1 
ATOM   3086 C CD2   . LEU A 1 446 ? 148.412 144.385 156.510 1.00 28.08  ? 446 LEU A CD2   1 
ATOM   3087 N N     . LEU A 1 447 ? 153.126 146.705 155.969 1.00 25.31  ? 447 LEU A N     1 
ATOM   3088 C CA    . LEU A 1 447 ? 154.484 146.837 156.486 1.00 25.70  ? 447 LEU A CA    1 
ATOM   3089 C C     . LEU A 1 447 ? 154.567 147.908 157.564 1.00 28.66  ? 447 LEU A C     1 
ATOM   3090 O O     . LEU A 1 447 ? 155.260 147.732 158.573 1.00 33.03  ? 447 LEU A O     1 
ATOM   3091 C CB    . LEU A 1 447 ? 155.449 147.141 155.346 1.00 29.61  ? 447 LEU A CB    1 
ATOM   3092 C CG    . LEU A 1 447 ? 155.896 145.909 154.565 1.00 34.10  ? 447 LEU A CG    1 
ATOM   3093 C CD1   . LEU A 1 447 ? 156.618 146.319 153.301 1.00 37.07  ? 447 LEU A CD1   1 
ATOM   3094 C CD2   . LEU A 1 447 ? 156.787 145.029 155.426 1.00 28.19  ? 447 LEU A CD2   1 
ATOM   3095 N N     . LYS A 1 448 ? 153.879 149.033 157.360 1.00 27.93  ? 448 LYS A N     1 
ATOM   3096 C CA    . LYS A 1 448 ? 153.770 150.039 158.412 1.00 29.98  ? 448 LYS A CA    1 
ATOM   3097 C C     . LYS A 1 448 ? 153.180 149.436 159.680 1.00 28.85  ? 448 LYS A C     1 
ATOM   3098 O O     . LYS A 1 448 ? 153.704 149.632 160.786 1.00 30.44  ? 448 LYS A O     1 
ATOM   3099 C CB    . LYS A 1 448 ? 152.916 151.211 157.932 1.00 29.51  ? 448 LYS A CB    1 
ATOM   3100 C CG    . LYS A 1 448 ? 152.559 152.193 159.031 1.00 30.54  ? 448 LYS A CG    1 
ATOM   3101 C CD    . LYS A 1 448 ? 151.190 152.784 158.800 1.00 32.78  ? 448 LYS A CD    1 
ATOM   3102 C CE    . LYS A 1 448 ? 150.143 151.691 158.710 1.00 32.56  ? 448 LYS A CE    1 
ATOM   3103 N NZ    . LYS A 1 448 ? 148.794 152.228 158.405 1.00 37.17  ? 448 LYS A NZ    1 
ATOM   3104 N N     . SER A 1 449 ? 152.080 148.693 159.531 1.00 25.68  ? 449 SER A N     1 
ATOM   3105 C CA    . SER A 1 449 ? 151.443 148.062 160.682 1.00 21.75  ? 449 SER A CA    1 
ATOM   3106 C C     . SER A 1 449 ? 152.375 147.066 161.361 1.00 24.22  ? 449 SER A C     1 
ATOM   3107 O O     . SER A 1 449 ? 152.417 146.990 162.590 1.00 27.51  ? 449 SER A O     1 
ATOM   3108 C CB    . SER A 1 449 ? 150.148 147.378 160.251 1.00 26.20  ? 449 SER A CB    1 
ATOM   3109 O OG    . SER A 1 449 ? 149.181 148.335 159.860 1.00 29.32  ? 449 SER A OG    1 
ATOM   3110 N N     . PHE A 1 450 ? 153.120 146.284 160.576 1.00 25.33  ? 450 PHE A N     1 
ATOM   3111 C CA    . PHE A 1 450 ? 154.045 145.305 161.141 1.00 28.92  ? 450 PHE A CA    1 
ATOM   3112 C C     . PHE A 1 450 ? 155.160 145.985 161.923 1.00 27.42  ? 450 PHE A C     1 
ATOM   3113 O O     . PHE A 1 450 ? 155.531 145.535 163.012 1.00 27.59  ? 450 PHE A O     1 
ATOM   3114 C CB    . PHE A 1 450 ? 154.650 144.439 160.035 1.00 26.15  ? 450 PHE A CB    1 
ATOM   3115 C CG    . PHE A 1 450 ? 153.657 143.592 159.292 1.00 26.81  ? 450 PHE A CG    1 
ATOM   3116 C CD1   . PHE A 1 450 ? 152.393 143.352 159.801 1.00 27.63  ? 450 PHE A CD1   1 
ATOM   3117 C CD2   . PHE A 1 450 ? 154.000 143.024 158.078 1.00 32.25  ? 450 PHE A CD2   1 
ATOM   3118 C CE1   . PHE A 1 450 ? 151.493 142.571 159.107 1.00 32.57  ? 450 PHE A CE1   1 
ATOM   3119 C CE2   . PHE A 1 450 ? 153.105 142.239 157.385 1.00 37.46  ? 450 PHE A CE2   1 
ATOM   3120 C CZ    . PHE A 1 450 ? 151.850 142.012 157.901 1.00 36.57  ? 450 PHE A CZ    1 
ATOM   3121 N N     . ALA A 1 451 ? 155.718 147.063 161.371 1.00 21.41  ? 451 ALA A N     1 
ATOM   3122 C CA    . ALA A 1 451 ? 156.773 147.785 162.071 1.00 19.54  ? 451 ALA A CA    1 
ATOM   3123 C C     . ALA A 1 451 ? 156.254 148.403 163.363 1.00 23.78  ? 451 ALA A C     1 
ATOM   3124 O O     . ALA A 1 451 ? 156.941 148.372 164.390 1.00 25.68  ? 451 ALA A O     1 
ATOM   3125 C CB    . ALA A 1 451 ? 157.373 148.854 161.161 1.00 25.33  ? 451 ALA A CB    1 
ATOM   3126 N N     . LEU A 1 452 ? 155.047 148.970 163.334 1.00 24.76  ? 452 LEU A N     1 
ATOM   3127 C CA    . LEU A 1 452 ? 154.486 149.537 164.555 1.00 24.56  ? 452 LEU A CA    1 
ATOM   3128 C C     . LEU A 1 452 ? 154.145 148.461 165.579 1.00 29.29  ? 452 LEU A C     1 
ATOM   3129 O O     . LEU A 1 452 ? 154.299 148.685 166.785 1.00 31.93  ? 452 LEU A O     1 
ATOM   3130 C CB    . LEU A 1 452 ? 153.254 150.377 164.225 1.00 27.01  ? 452 LEU A CB    1 
ATOM   3131 C CG    . LEU A 1 452 ? 153.537 151.609 163.367 1.00 31.53  ? 452 LEU A CG    1 
ATOM   3132 C CD1   . LEU A 1 452 ? 152.276 152.430 163.174 1.00 33.37  ? 452 LEU A CD1   1 
ATOM   3133 C CD2   . LEU A 1 452 ? 154.642 152.446 163.984 1.00 30.71  ? 452 LEU A CD2   1 
ATOM   3134 N N     . MET A 1 453 ? 153.682 147.294 165.125 1.00 28.94  ? 453 MET A N     1 
ATOM   3135 C CA    . MET A 1 453 ? 153.354 146.207 166.041 1.00 22.22  ? 453 MET A CA    1 
ATOM   3136 C C     . MET A 1 453 ? 154.596 145.620 166.689 1.00 23.97  ? 453 MET A C     1 
ATOM   3137 O O     . MET A 1 453 ? 154.523 145.105 167.809 1.00 23.48  ? 453 MET A O     1 
ATOM   3138 C CB    . MET A 1 453 ? 152.607 145.092 165.311 1.00 21.34  ? 453 MET A CB    1 
ATOM   3139 C CG    . MET A 1 453 ? 151.180 145.381 164.932 1.00 24.45  ? 453 MET A CG    1 
ATOM   3140 S SD    . MET A 1 453 ? 150.477 143.929 164.130 1.00 49.12  ? 453 MET A SD    1 
ATOM   3141 C CE    . MET A 1 453 ? 149.150 144.654 163.184 1.00 31.53  ? 453 MET A CE    1 
ATOM   3142 N N     . GLY A 1 454 ? 155.736 145.680 166.010 1.00 28.37  ? 454 GLY A N     1 
ATOM   3143 C CA    . GLY A 1 454 ? 156.906 144.963 166.470 1.00 28.14  ? 454 GLY A CA    1 
ATOM   3144 C C     . GLY A 1 454 ? 156.964 143.528 166.017 1.00 27.72  ? 454 GLY A C     1 
ATOM   3145 O O     . GLY A 1 454 ? 157.705 142.733 166.604 1.00 31.59  ? 454 GLY A O     1 
ATOM   3146 N N     . LEU A 1 455 ? 156.195 143.168 164.995 1.00 23.24  ? 455 LEU A N     1 
ATOM   3147 C CA    . LEU A 1 455 ? 156.227 141.815 164.462 1.00 20.00  ? 455 LEU A CA    1 
ATOM   3148 C C     . LEU A 1 455 ? 157.589 141.528 163.850 1.00 18.65  ? 455 LEU A C     1 
ATOM   3149 O O     . LEU A 1 455 ? 158.021 142.217 162.921 1.00 23.66  ? 455 LEU A O     1 
ATOM   3150 C CB    . LEU A 1 455 ? 155.119 141.643 163.424 1.00 26.56  ? 455 LEU A CB    1 
ATOM   3151 C CG    . LEU A 1 455 ? 154.831 140.234 162.905 1.00 26.47  ? 455 LEU A CG    1 
ATOM   3152 C CD1   . LEU A 1 455 ? 153.346 140.079 162.662 1.00 27.75  ? 455 LEU A CD1   1 
ATOM   3153 C CD2   . LEU A 1 455 ? 155.597 139.938 161.630 1.00 26.85  ? 455 LEU A CD2   1 
ATOM   3154 N N     . GLY A 1 456 ? 158.262 140.505 164.367 1.00 19.18  ? 456 GLY A N     1 
ATOM   3155 C CA    . GLY A 1 456 ? 159.589 140.171 163.898 1.00 23.39  ? 456 GLY A CA    1 
ATOM   3156 C C     . GLY A 1 456 ? 160.709 140.963 164.525 1.00 23.72  ? 456 GLY A C     1 
ATOM   3157 O O     . GLY A 1 456 ? 161.837 140.919 164.027 1.00 26.74  ? 456 GLY A O     1 
ATOM   3158 N N     . ALA A 1 457 ? 160.437 141.684 165.611 1.00 23.70  ? 457 ALA A N     1 
ATOM   3159 C CA    . ALA A 1 457 ? 161.482 142.464 166.261 1.00 26.78  ? 457 ALA A CA    1 
ATOM   3160 C C     . ALA A 1 457 ? 162.531 141.579 166.922 1.00 30.07  ? 457 ALA A C     1 
ATOM   3161 O O     . ALA A 1 457 ? 163.719 141.920 166.915 1.00 30.77  ? 457 ALA A O     1 
ATOM   3162 C CB    . ALA A 1 457 ? 160.861 143.408 167.288 1.00 29.34  ? 457 ALA A CB    1 
ATOM   3163 N N     . GLY A 1 458 ? 162.122 140.445 167.493 1.00 32.28  ? 458 GLY A N     1 
ATOM   3164 C CA    . GLY A 1 458 ? 163.012 139.599 168.255 1.00 36.51  ? 458 GLY A CA    1 
ATOM   3165 C C     . GLY A 1 458 ? 163.669 138.518 167.410 1.00 40.85  ? 458 GLY A C     1 
ATOM   3166 O O     . GLY A 1 458 ? 163.506 138.441 166.195 1.00 42.84  ? 458 GLY A O     1 
ATOM   3167 N N     . ASP A 1 459 ? 164.433 137.670 168.093 1.00 44.01  ? 459 ASP A N     1 
ATOM   3168 C CA    . ASP A 1 459 ? 165.129 136.582 167.423 1.00 48.23  ? 459 ASP A CA    1 
ATOM   3169 C C     . ASP A 1 459 ? 164.135 135.563 166.881 1.00 48.68  ? 459 ASP A C     1 
ATOM   3170 O O     . ASP A 1 459 ? 163.071 135.328 167.459 1.00 46.33  ? 459 ASP A O     1 
ATOM   3171 C CB    . ASP A 1 459 ? 166.111 135.898 168.374 1.00 55.72  ? 459 ASP A CB    1 
ATOM   3172 C CG    . ASP A 1 459 ? 165.416 135.151 169.498 1.00 60.62  ? 459 ASP A CG    1 
ATOM   3173 O OD1   . ASP A 1 459 ? 164.591 135.766 170.207 1.00 61.54  ? 459 ASP A OD1   1 
ATOM   3174 O OD2   . ASP A 1 459 ? 165.690 133.944 169.667 1.00 56.76  ? 459 ASP A OD2   1 
ATOM   3175 N N     . GLY A 1 460 ? 164.490 134.960 165.748 1.00 48.94  ? 460 GLY A N     1 
ATOM   3176 C CA    . GLY A 1 460 ? 163.626 134.013 165.083 1.00 49.43  ? 460 GLY A CA    1 
ATOM   3177 C C     . GLY A 1 460 ? 162.491 134.625 164.296 1.00 45.52  ? 460 GLY A C     1 
ATOM   3178 O O     . GLY A 1 460 ? 161.993 133.990 163.359 1.00 46.02  ? 460 GLY A O     1 
ATOM   3179 N N     . GLY A 1 461 ? 162.061 135.840 164.641 1.00 35.36  ? 461 GLY A N     1 
ATOM   3180 C CA    . GLY A 1 461 ? 161.008 136.498 163.901 1.00 29.54  ? 461 GLY A CA    1 
ATOM   3181 C C     . GLY A 1 461 ? 161.533 137.336 162.751 1.00 26.84  ? 461 GLY A C     1 
ATOM   3182 O O     . GLY A 1 461 ? 162.731 137.551 162.599 1.00 32.33  ? 461 GLY A O     1 
ATOM   3183 N N     . GLY A 1 462 ? 160.599 137.810 161.936 1.00 25.53  ? 462 GLY A N     1 
ATOM   3184 C CA    . GLY A 1 462 ? 160.940 138.663 160.819 1.00 24.00  ? 462 GLY A CA    1 
ATOM   3185 C C     . GLY A 1 462 ? 159.764 138.791 159.872 1.00 25.74  ? 462 GLY A C     1 
ATOM   3186 O O     . GLY A 1 462 ? 158.662 138.317 160.152 1.00 31.84  ? 462 GLY A O     1 
ATOM   3187 N N     . VAL A 1 463 ? 160.019 139.457 158.751 1.00 21.68  ? 463 VAL A N     1 
ATOM   3188 C CA    . VAL A 1 463 ? 159.065 139.546 157.652 1.00 21.04  ? 463 VAL A CA    1 
ATOM   3189 C C     . VAL A 1 463 ? 159.833 139.323 156.359 1.00 28.30  ? 463 VAL A C     1 
ATOM   3190 O O     . VAL A 1 463 ? 160.949 139.824 156.203 1.00 33.36  ? 463 VAL A O     1 
ATOM   3191 C CB    . VAL A 1 463 ? 158.329 140.906 157.619 1.00 17.95  ? 463 VAL A CB    1 
ATOM   3192 C CG1   . VAL A 1 463 ? 157.282 140.928 156.522 1.00 20.13  ? 463 VAL A CG1   1 
ATOM   3193 C CG2   . VAL A 1 463 ? 157.689 141.220 158.958 1.00 23.12  ? 463 VAL A CG2   1 
ATOM   3194 N N     . THR A 1 464 ? 159.258 138.546 155.450 1.00 26.04  ? 464 THR A N     1 
ATOM   3195 C CA    . THR A 1 464 ? 159.759 138.444 154.087 1.00 26.45  ? 464 THR A CA    1 
ATOM   3196 C C     . THR A 1 464 ? 158.770 139.114 153.142 1.00 31.47  ? 464 THR A C     1 
ATOM   3197 O O     . THR A 1 464 ? 157.599 138.728 153.091 1.00 33.85  ? 464 THR A O     1 
ATOM   3198 C CB    . THR A 1 464 ? 159.970 136.984 153.688 1.00 31.11  ? 464 THR A CB    1 
ATOM   3199 O OG1   . THR A 1 464 ? 161.104 136.457 154.389 1.00 41.08  ? 464 THR A OG1   1 
ATOM   3200 C CG2   . THR A 1 464 ? 160.201 136.863 152.191 1.00 32.66  ? 464 THR A CG2   1 
ATOM   3201 N N     . VAL A 1 465 ? 159.239 140.106 152.388 1.00 31.58  ? 465 VAL A N     1 
ATOM   3202 C CA    . VAL A 1 465 ? 158.399 140.816 151.428 1.00 27.39  ? 465 VAL A CA    1 
ATOM   3203 C C     . VAL A 1 465 ? 158.829 140.418 150.023 1.00 34.58  ? 465 VAL A C     1 
ATOM   3204 O O     . VAL A 1 465 ? 159.998 140.577 149.652 1.00 36.69  ? 465 VAL A O     1 
ATOM   3205 C CB    . VAL A 1 465 ? 158.464 142.340 151.629 1.00 34.23  ? 465 VAL A CB    1 
ATOM   3206 C CG1   . VAL A 1 465 ? 159.903 142.825 151.694 1.00 38.49  ? 465 VAL A CG1   1 
ATOM   3207 C CG2   . VAL A 1 465 ? 157.698 143.057 150.527 1.00 37.98  ? 465 VAL A CG2   1 
ATOM   3208 N N     . ALA A 1 466 ? 157.882 139.906 149.239 1.00 41.20  ? 466 ALA A N     1 
ATOM   3209 C CA    . ALA A 1 466 ? 158.151 139.382 147.906 1.00 39.19  ? 466 ALA A CA    1 
ATOM   3210 C C     . ALA A 1 466 ? 157.346 140.161 146.876 1.00 37.85  ? 466 ALA A C     1 
ATOM   3211 O O     . ALA A 1 466 ? 156.112 140.178 146.936 1.00 41.97  ? 466 ALA A O     1 
ATOM   3212 C CB    . ALA A 1 466 ? 157.812 137.892 147.829 1.00 39.42  ? 466 ALA A CB    1 
ATOM   3213 N N     . ASP A 1 467 ? 158.042 140.790 145.931 1.00 36.35  ? 467 ASP A N     1 
ATOM   3214 C CA    . ASP A 1 467 ? 157.390 141.463 144.816 1.00 40.45  ? 467 ASP A CA    1 
ATOM   3215 C C     . ASP A 1 467 ? 158.397 141.630 143.687 1.00 51.95  ? 467 ASP A C     1 
ATOM   3216 O O     . ASP A 1 467 ? 159.559 141.964 143.930 1.00 51.26  ? 467 ASP A O     1 
ATOM   3217 C CB    . ASP A 1 467 ? 156.820 142.822 145.234 1.00 42.65  ? 467 ASP A CB    1 
ATOM   3218 C CG    . ASP A 1 467 ? 155.717 143.305 144.311 1.00 46.82  ? 467 ASP A CG    1 
ATOM   3219 O OD1   . ASP A 1 467 ? 155.772 143.025 143.098 1.00 48.22  ? 467 ASP A OD1   1 
ATOM   3220 O OD2   . ASP A 1 467 ? 154.786 143.970 144.802 1.00 49.08  ? 467 ASP A OD2   1 
ATOM   3221 N N     . MET A 1 468 ? 157.944 141.382 142.456 1.00 55.11  ? 468 MET A N     1 
ATOM   3222 C CA    . MET A 1 468 ? 158.794 141.510 141.278 1.00 53.60  ? 468 MET A CA    1 
ATOM   3223 C C     . MET A 1 468 ? 158.709 142.886 140.635 1.00 58.77  ? 468 MET A C     1 
ATOM   3224 O O     . MET A 1 468 ? 159.692 143.347 140.043 1.00 62.11  ? 468 MET A O     1 
ATOM   3225 C CB    . MET A 1 468 ? 158.419 140.442 140.244 1.00 52.82  ? 468 MET A CB    1 
ATOM   3226 C CG    . MET A 1 468 ? 159.370 140.316 139.056 1.00 66.06  ? 468 MET A CG    1 
ATOM   3227 S SD    . MET A 1 468 ? 159.069 141.468 137.694 1.00 96.80  ? 468 MET A SD    1 
ATOM   3228 C CE    . MET A 1 468 ? 157.286 141.386 137.544 1.00 76.23  ? 468 MET A CE    1 
ATOM   3229 N N     . ASP A 1 469 ? 157.567 143.554 140.751 1.00 56.91  ? 469 ASP A N     1 
ATOM   3230 C CA    . ASP A 1 469 ? 157.333 144.786 140.016 1.00 56.52  ? 469 ASP A CA    1 
ATOM   3231 C C     . ASP A 1 469 ? 158.232 145.910 140.520 1.00 58.12  ? 469 ASP A C     1 
ATOM   3232 O O     . ASP A 1 469 ? 158.647 145.935 141.682 1.00 58.96  ? 469 ASP A O     1 
ATOM   3233 C CB    . ASP A 1 469 ? 155.868 145.198 140.133 1.00 58.36  ? 469 ASP A CB    1 
ATOM   3234 C CG    . ASP A 1 469 ? 155.445 146.161 139.045 1.00 71.37  ? 469 ASP A CG    1 
ATOM   3235 O OD1   . ASP A 1 469 ? 156.186 146.297 138.048 1.00 72.95  ? 469 ASP A OD1   1 
ATOM   3236 O OD2   . ASP A 1 469 ? 154.372 146.782 139.188 1.00 71.63  ? 469 ASP A OD2   1 
ATOM   3237 N N     . HIS A 1 470 ? 158.536 146.841 139.621 1.00 55.28  ? 470 HIS A N     1 
ATOM   3238 C CA    . HIS A 1 470 ? 159.325 148.023 139.930 1.00 49.43  ? 470 HIS A CA    1 
ATOM   3239 C C     . HIS A 1 470 ? 158.420 149.172 140.358 1.00 56.81  ? 470 HIS A C     1 
ATOM   3240 O O     . HIS A 1 470 ? 157.202 149.146 140.166 1.00 62.81  ? 470 HIS A O     1 
ATOM   3241 C CB    . HIS A 1 470 ? 160.160 148.454 138.724 1.00 46.38  ? 470 HIS A CB    1 
ATOM   3242 C CG    . HIS A 1 470 ? 161.446 147.706 138.571 1.00 52.98  ? 470 HIS A CG    1 
ATOM   3243 N ND1   . HIS A 1 470 ? 162.465 147.778 139.496 1.00 60.01  ? 470 HIS A ND1   1 
ATOM   3244 C CD2   . HIS A 1 470 ? 161.890 146.890 137.586 1.00 61.33  ? 470 HIS A CD2   1 
ATOM   3245 C CE1   . HIS A 1 470 ? 163.476 147.029 139.093 1.00 61.88  ? 470 HIS A CE1   1 
ATOM   3246 N NE2   . HIS A 1 470 ? 163.152 146.478 137.938 1.00 65.27  ? 470 HIS A NE2   1 
ATOM   3247 N N     . VAL A 1 471 ? 159.038 150.195 140.943 1.00 56.28  ? 471 VAL A N     1 
ATOM   3248 C CA    . VAL A 1 471 ? 158.313 151.385 141.371 1.00 58.11  ? 471 VAL A CA    1 
ATOM   3249 C C     . VAL A 1 471 ? 158.080 152.302 140.177 1.00 62.60  ? 471 VAL A C     1 
ATOM   3250 O O     . VAL A 1 471 ? 158.973 153.052 139.770 1.00 60.34  ? 471 VAL A O     1 
ATOM   3251 C CB    . VAL A 1 471 ? 159.066 152.120 142.494 1.00 59.36  ? 471 VAL A CB    1 
ATOM   3252 C CG1   . VAL A 1 471 ? 158.328 153.393 142.882 1.00 65.03  ? 471 VAL A CG1   1 
ATOM   3253 C CG2   . VAL A 1 471 ? 159.231 151.212 143.701 1.00 55.93  ? 471 VAL A CG2   1 
ATOM   3254 N N     . GLU A 1 472 ? 156.883 152.241 139.605 1.00 68.06  ? 472 GLU A N     1 
ATOM   3255 C CA    . GLU A 1 472 ? 156.481 153.199 138.592 1.00 72.77  ? 472 GLU A CA    1 
ATOM   3256 C C     . GLU A 1 472 ? 156.103 154.525 139.245 1.00 75.49  ? 472 GLU A C     1 
ATOM   3257 O O     . GLU A 1 472 ? 155.798 154.595 140.438 1.00 75.23  ? 472 GLU A O     1 
ATOM   3258 C CB    . GLU A 1 472 ? 155.307 152.660 137.774 1.00 81.23  ? 472 GLU A CB    1 
ATOM   3259 C CG    . GLU A 1 472 ? 155.686 151.574 136.778 1.00 89.29  ? 472 GLU A CG    1 
ATOM   3260 C CD    . GLU A 1 472 ? 156.482 152.108 135.599 1.00 98.15  ? 472 GLU A CD    1 
ATOM   3261 O OE1   . GLU A 1 472 ? 156.513 153.341 135.401 1.00 94.87  ? 472 GLU A OE1   1 
ATOM   3262 O OE2   . GLU A 1 472 ? 157.077 151.290 134.866 1.00 100.69 ? 472 GLU A OE2   1 
ATOM   3263 N N     . LEU A 1 473 ? 156.138 155.592 138.443 1.00 76.99  ? 473 LEU A N     1 
ATOM   3264 C CA    . LEU A 1 473 ? 155.732 156.898 138.950 1.00 73.81  ? 473 LEU A CA    1 
ATOM   3265 C C     . LEU A 1 473 ? 154.269 156.901 139.378 1.00 72.54  ? 473 LEU A C     1 
ATOM   3266 O O     . LEU A 1 473 ? 153.892 157.645 140.291 1.00 72.60  ? 473 LEU A O     1 
ATOM   3267 C CB    . LEU A 1 473 ? 155.991 157.974 137.894 1.00 78.48  ? 473 LEU A CB    1 
ATOM   3268 C CG    . LEU A 1 473 ? 155.716 159.422 138.307 1.00 84.64  ? 473 LEU A CG    1 
ATOM   3269 C CD1   . LEU A 1 473 ? 156.514 159.785 139.552 1.00 81.33  ? 473 LEU A CD1   1 
ATOM   3270 C CD2   . LEU A 1 473 ? 156.027 160.390 137.169 1.00 84.97  ? 473 LEU A CD2   1 
ATOM   3271 N N     . SER A 1 474 ? 153.435 156.068 138.750 1.00 74.27  ? 474 SER A N     1 
ATOM   3272 C CA    . SER A 1 474 ? 152.033 155.966 139.140 1.00 80.41  ? 474 SER A CA    1 
ATOM   3273 C C     . SER A 1 474 ? 151.846 155.321 140.508 1.00 80.59  ? 474 SER A C     1 
ATOM   3274 O O     . SER A 1 474 ? 150.760 155.439 141.087 1.00 78.32  ? 474 SER A O     1 
ATOM   3275 C CB    . SER A 1 474 ? 151.256 155.180 138.081 1.00 82.09  ? 474 SER A CB    1 
ATOM   3276 O OG    . SER A 1 474 ? 151.763 153.863 137.949 1.00 80.94  ? 474 SER A OG    1 
ATOM   3277 N N     . ASN A 1 475 ? 152.872 154.661 141.043 1.00 79.10  ? 475 ASN A N     1 
ATOM   3278 C CA    . ASN A 1 475 ? 152.789 154.079 142.375 1.00 79.47  ? 475 ASN A CA    1 
ATOM   3279 C C     . ASN A 1 475 ? 152.971 155.109 143.480 1.00 78.76  ? 475 ASN A C     1 
ATOM   3280 O O     . ASN A 1 475 ? 152.620 154.832 144.632 1.00 72.48  ? 475 ASN A O     1 
ATOM   3281 C CB    . ASN A 1 475 ? 153.837 152.973 142.544 1.00 76.27  ? 475 ASN A CB    1 
ATOM   3282 C CG    . ASN A 1 475 ? 153.711 151.875 141.502 1.00 78.05  ? 475 ASN A CG    1 
ATOM   3283 O OD1   . ASN A 1 475 ? 154.706 151.283 141.094 1.00 74.91  ? 475 ASN A OD1   1 
ATOM   3284 N ND2   . ASN A 1 475 ? 152.489 151.599 141.065 1.00 81.86  ? 475 ASN A ND2   1 
ATOM   3285 N N     . LEU A 1 476 ? 153.534 156.270 143.165 1.00 79.85  ? 476 LEU A N     1 
ATOM   3286 C CA    . LEU A 1 476 ? 153.610 157.342 144.140 1.00 77.85  ? 476 LEU A CA    1 
ATOM   3287 C C     . LEU A 1 476 ? 152.254 158.027 144.280 1.00 75.58  ? 476 LEU A C     1 
ATOM   3288 O O     . LEU A 1 476 ? 151.405 157.974 143.385 1.00 75.35  ? 476 LEU A O     1 
ATOM   3289 C CB    . LEU A 1 476 ? 154.678 158.360 143.743 1.00 78.11  ? 476 LEU A CB    1 
ATOM   3290 C CG    . LEU A 1 476 ? 156.122 158.047 144.138 1.00 75.88  ? 476 LEU A CG    1 
ATOM   3291 C CD1   . LEU A 1 476 ? 156.680 156.832 143.403 1.00 73.34  ? 476 LEU A CD1   1 
ATOM   3292 C CD2   . LEU A 1 476 ? 156.975 159.271 143.880 1.00 76.59  ? 476 LEU A CD2   1 
ATOM   3293 N N     . SER A 1 477 ? 152.053 158.644 145.444 1.00 74.93  ? 477 SER A N     1 
ATOM   3294 C CA    . SER A 1 477 ? 150.860 159.413 145.787 1.00 76.64  ? 477 SER A CA    1 
ATOM   3295 C C     . SER A 1 477 ? 149.639 158.514 145.956 1.00 72.57  ? 477 SER A C     1 
ATOM   3296 O O     . SER A 1 477 ? 148.563 158.989 146.338 1.00 73.05  ? 477 SER A O     1 
ATOM   3297 C CB    . SER A 1 477 ? 150.588 160.500 144.741 1.00 80.50  ? 477 SER A CB    1 
ATOM   3298 O OG    . SER A 1 477 ? 149.600 160.092 143.814 1.00 78.22  ? 477 SER A OG    1 
ATOM   3299 N N     . ARG A 1 478 ? 149.789 157.221 145.683 1.00 70.51  ? 478 ARG A N     1 
ATOM   3300 C CA    . ARG A 1 478 ? 148.834 156.221 146.136 1.00 68.21  ? 478 ARG A CA    1 
ATOM   3301 C C     . ARG A 1 478 ? 149.345 155.449 147.345 1.00 66.74  ? 478 ARG A C     1 
ATOM   3302 O O     . ARG A 1 478 ? 148.612 154.623 147.897 1.00 66.24  ? 478 ARG A O     1 
ATOM   3303 C CB    . ARG A 1 478 ? 148.484 155.250 144.994 1.00 73.31  ? 478 ARG A CB    1 
ATOM   3304 C CG    . ARG A 1 478 ? 149.600 154.309 144.573 1.00 79.07  ? 478 ARG A CG    1 
ATOM   3305 C CD    . ARG A 1 478 ? 149.249 153.572 143.284 1.00 81.14  ? 478 ARG A CD    1 
ATOM   3306 N NE    . ARG A 1 478 ? 148.104 152.684 143.451 1.00 81.10  ? 478 ARG A NE    1 
ATOM   3307 C CZ    . ARG A 1 478 ? 148.193 151.371 143.608 1.00 80.92  ? 478 ARG A CZ    1 
ATOM   3308 N NH1   . ARG A 1 478 ? 149.363 150.752 143.609 1.00 79.39  ? 478 ARG A NH1   1 
ATOM   3309 N NH2   . ARG A 1 478 ? 147.081 150.659 143.762 1.00 78.57  ? 478 ARG A NH2   1 
ATOM   3310 N N     . GLN A 1 479 ? 150.580 155.708 147.768 1.00 68.20  ? 479 GLN A N     1 
ATOM   3311 C CA    . GLN A 1 479 ? 151.164 155.066 148.935 1.00 67.65  ? 479 GLN A CA    1 
ATOM   3312 C C     . GLN A 1 479 ? 152.311 155.931 149.437 1.00 61.12  ? 479 GLN A C     1 
ATOM   3313 O O     . GLN A 1 479 ? 152.978 156.610 148.653 1.00 62.21  ? 479 GLN A O     1 
ATOM   3314 C CB    . GLN A 1 479 ? 151.653 153.652 148.612 1.00 67.48  ? 479 GLN A CB    1 
ATOM   3315 C CG    . GLN A 1 479 ? 152.046 152.851 149.834 1.00 71.13  ? 479 GLN A CG    1 
ATOM   3316 C CD    . GLN A 1 479 ? 150.913 152.706 150.837 1.00 72.55  ? 479 GLN A CD    1 
ATOM   3317 O OE1   . GLN A 1 479 ? 151.135 152.744 152.046 1.00 70.31  ? 479 GLN A OE1   1 
ATOM   3318 N NE2   . GLN A 1 479 ? 149.695 152.535 150.343 1.00 68.91  ? 479 GLN A NE2   1 
ATOM   3319 N N     . PHE A 1 480 ? 152.537 155.892 150.752 1.00 56.79  ? 480 PHE A N     1 
ATOM   3320 C CA    . PHE A 1 480 ? 153.512 156.768 151.390 1.00 56.58  ? 480 PHE A CA    1 
ATOM   3321 C C     . PHE A 1 480 ? 154.929 156.207 151.398 1.00 58.80  ? 480 PHE A C     1 
ATOM   3322 O O     . PHE A 1 480 ? 155.855 156.923 151.795 1.00 62.40  ? 480 PHE A O     1 
ATOM   3323 C CB    . PHE A 1 480 ? 153.083 157.069 152.828 1.00 55.42  ? 480 PHE A CB    1 
ATOM   3324 C CG    . PHE A 1 480 ? 153.443 155.988 153.807 1.00 47.86  ? 480 PHE A CG    1 
ATOM   3325 C CD1   . PHE A 1 480 ? 152.774 154.779 153.801 1.00 44.83  ? 480 PHE A CD1   1 
ATOM   3326 C CD2   . PHE A 1 480 ? 154.446 156.188 154.742 1.00 51.48  ? 480 PHE A CD2   1 
ATOM   3327 C CE1   . PHE A 1 480 ? 153.099 153.785 154.702 1.00 48.26  ? 480 PHE A CE1   1 
ATOM   3328 C CE2   . PHE A 1 480 ? 154.777 155.197 155.648 1.00 54.04  ? 480 PHE A CE2   1 
ATOM   3329 C CZ    . PHE A 1 480 ? 154.101 153.994 155.627 1.00 53.89  ? 480 PHE A CZ    1 
ATOM   3330 N N     . LEU A 1 481 ? 155.129 154.962 150.977 1.00 59.32  ? 481 LEU A N     1 
ATOM   3331 C CA    . LEU A 1 481 ? 156.419 154.306 151.147 1.00 58.90  ? 481 LEU A CA    1 
ATOM   3332 C C     . LEU A 1 481 ? 157.422 154.626 150.045 1.00 66.22  ? 481 LEU A C     1 
ATOM   3333 O O     . LEU A 1 481 ? 158.529 154.077 150.068 1.00 73.59  ? 481 LEU A O     1 
ATOM   3334 C CB    . LEU A 1 481 ? 156.223 152.790 151.232 1.00 53.03  ? 481 LEU A CB    1 
ATOM   3335 C CG    . LEU A 1 481 ? 157.054 152.114 152.322 1.00 50.72  ? 481 LEU A CG    1 
ATOM   3336 C CD1   . LEU A 1 481 ? 156.734 152.712 153.682 1.00 48.68  ? 481 LEU A CD1   1 
ATOM   3337 C CD2   . LEU A 1 481 ? 156.820 150.620 152.342 1.00 51.95  ? 481 LEU A CD2   1 
ATOM   3338 N N     . PHE A 1 482 ? 157.087 155.492 149.090 1.00 61.63  ? 482 PHE A N     1 
ATOM   3339 C CA    . PHE A 1 482 ? 157.949 155.726 147.939 1.00 65.94  ? 482 PHE A CA    1 
ATOM   3340 C C     . PHE A 1 482 ? 158.152 157.217 147.702 1.00 70.51  ? 482 PHE A C     1 
ATOM   3341 O O     . PHE A 1 482 ? 157.249 158.025 147.942 1.00 74.48  ? 482 PHE A O     1 
ATOM   3342 C CB    . PHE A 1 482 ? 157.372 155.062 146.679 1.00 70.53  ? 482 PHE A CB    1 
ATOM   3343 C CG    . PHE A 1 482 ? 157.039 153.603 146.857 1.00 66.78  ? 482 PHE A CG    1 
ATOM   3344 C CD1   . PHE A 1 482 ? 158.041 152.643 146.890 1.00 59.05  ? 482 PHE A CD1   1 
ATOM   3345 C CD2   . PHE A 1 482 ? 155.723 153.191 146.981 1.00 67.93  ? 482 PHE A CD2   1 
ATOM   3346 C CE1   . PHE A 1 482 ? 157.734 151.305 147.050 1.00 55.85  ? 482 PHE A CE1   1 
ATOM   3347 C CE2   . PHE A 1 482 ? 155.411 151.854 147.141 1.00 63.68  ? 482 PHE A CE2   1 
ATOM   3348 C CZ    . PHE A 1 482 ? 156.419 150.910 147.174 1.00 58.58  ? 482 PHE A CZ    1 
ATOM   3349 N N     . ARG A 1 483 ? 159.346 157.572 147.227 1.00 73.39  ? 483 ARG A N     1 
ATOM   3350 C CA    . ARG A 1 483 ? 159.726 158.944 146.910 1.00 77.08  ? 483 ARG A CA    1 
ATOM   3351 C C     . ARG A 1 483 ? 160.367 158.981 145.525 1.00 76.00  ? 483 ARG A C     1 
ATOM   3352 O O     . ARG A 1 483 ? 160.419 157.974 144.812 1.00 75.48  ? 483 ARG A O     1 
ATOM   3353 C CB    . ARG A 1 483 ? 160.677 159.525 147.965 1.00 77.46  ? 483 ARG A CB    1 
ATOM   3354 C CG    . ARG A 1 483 ? 160.011 159.914 149.281 1.00 78.65  ? 483 ARG A CG    1 
ATOM   3355 C CD    . ARG A 1 483 ? 159.974 158.758 150.280 1.00 79.84  ? 483 ARG A CD    1 
ATOM   3356 N NE    . ARG A 1 483 ? 159.326 159.137 151.532 1.00 72.68  ? 483 ARG A NE    1 
ATOM   3357 C CZ    . ARG A 1 483 ? 159.902 159.853 152.488 1.00 75.56  ? 483 ARG A CZ    1 
ATOM   3358 N NH1   . ARG A 1 483 ? 161.145 160.290 152.371 1.00 69.14  ? 483 ARG A NH1   1 
ATOM   3359 N NH2   . ARG A 1 483 ? 159.211 160.145 153.586 1.00 78.23  ? 483 ARG A NH2   1 
ATOM   3360 N N     . SER A 1 484 ? 160.850 160.166 145.138 1.00 73.34  ? 484 SER A N     1 
ATOM   3361 C CA    . SER A 1 484 ? 161.425 160.337 143.807 1.00 77.25  ? 484 SER A CA    1 
ATOM   3362 C C     . SER A 1 484 ? 162.669 159.484 143.604 1.00 75.83  ? 484 SER A C     1 
ATOM   3363 O O     . SER A 1 484 ? 162.889 158.964 142.504 1.00 79.51  ? 484 SER A O     1 
ATOM   3364 C CB    . SER A 1 484 ? 161.762 161.807 143.556 1.00 85.00  ? 484 SER A CB    1 
ATOM   3365 O OG    . SER A 1 484 ? 160.622 162.633 143.706 1.00 84.03  ? 484 SER A OG    1 
ATOM   3366 N N     . GLN A 1 485 ? 163.500 159.333 144.636 1.00 71.36  ? 485 GLN A N     1 
ATOM   3367 C CA    . GLN A 1 485 ? 164.731 158.569 144.473 1.00 74.06  ? 485 GLN A CA    1 
ATOM   3368 C C     . GLN A 1 485 ? 164.481 157.071 144.355 1.00 75.72  ? 485 GLN A C     1 
ATOM   3369 O O     . GLN A 1 485 ? 165.421 156.324 144.064 1.00 73.68  ? 485 GLN A O     1 
ATOM   3370 C CB    . GLN A 1 485 ? 165.689 158.854 145.634 1.00 72.35  ? 485 GLN A CB    1 
ATOM   3371 C CG    . GLN A 1 485 ? 165.125 158.577 147.015 1.00 72.54  ? 485 GLN A CG    1 
ATOM   3372 C CD    . GLN A 1 485 ? 164.619 159.829 147.701 1.00 77.33  ? 485 GLN A CD    1 
ATOM   3373 O OE1   . GLN A 1 485 ? 163.764 160.540 147.176 1.00 77.19  ? 485 GLN A OE1   1 
ATOM   3374 N NE2   . GLN A 1 485 ? 165.151 160.110 148.884 1.00 78.19  ? 485 GLN A NE2   1 
ATOM   3375 N N     . ASP A 1 486 ? 163.243 156.623 144.551 1.00 77.14  ? 486 ASP A N     1 
ATOM   3376 C CA    . ASP A 1 486 ? 162.891 155.211 144.515 1.00 70.83  ? 486 ASP A CA    1 
ATOM   3377 C C     . ASP A 1 486 ? 162.320 154.762 143.175 1.00 65.26  ? 486 ASP A C     1 
ATOM   3378 O O     . ASP A 1 486 ? 161.973 153.585 143.035 1.00 64.99  ? 486 ASP A O     1 
ATOM   3379 C CB    . ASP A 1 486 ? 161.889 154.907 145.633 1.00 68.80  ? 486 ASP A CB    1 
ATOM   3380 C CG    . ASP A 1 486 ? 162.389 155.355 146.993 1.00 66.80  ? 486 ASP A CG    1 
ATOM   3381 O OD1   . ASP A 1 486 ? 163.541 155.024 147.339 1.00 68.31  ? 486 ASP A OD1   1 
ATOM   3382 O OD2   . ASP A 1 486 ? 161.642 156.051 147.709 1.00 64.75  ? 486 ASP A OD2   1 
ATOM   3383 N N     . ILE A 1 487 ? 162.212 155.667 142.199 1.00 63.03  ? 487 ILE A N     1 
ATOM   3384 C CA    . ILE A 1 487 ? 161.632 155.324 140.906 1.00 65.32  ? 487 ILE A CA    1 
ATOM   3385 C C     . ILE A 1 487 ? 162.445 154.226 140.230 1.00 67.47  ? 487 ILE A C     1 
ATOM   3386 O O     . ILE A 1 487 ? 163.679 154.197 140.309 1.00 70.26  ? 487 ILE A O     1 
ATOM   3387 C CB    . ILE A 1 487 ? 161.538 156.580 140.024 1.00 72.77  ? 487 ILE A CB    1 
ATOM   3388 C CG1   . ILE A 1 487 ? 160.611 157.612 140.667 1.00 77.07  ? 487 ILE A CG1   1 
ATOM   3389 C CG2   . ILE A 1 487 ? 161.039 156.233 138.632 1.00 70.26  ? 487 ILE A CG2   1 
ATOM   3390 C CD1   . ILE A 1 487 ? 159.174 157.154 140.785 1.00 76.58  ? 487 ILE A CD1   1 
ATOM   3391 N N     . HIS A 1 488 ? 161.733 153.293 139.596 1.00 67.46  ? 488 HIS A N     1 
ATOM   3392 C CA    . HIS A 1 488 ? 162.233 152.162 138.814 1.00 66.22  ? 488 HIS A CA    1 
ATOM   3393 C C     . HIS A 1 488 ? 163.127 151.216 139.611 1.00 62.26  ? 488 HIS A C     1 
ATOM   3394 O O     . HIS A 1 488 ? 163.732 150.309 139.028 1.00 63.41  ? 488 HIS A O     1 
ATOM   3395 C CB    . HIS A 1 488 ? 162.942 152.617 137.520 1.00 66.02  ? 488 HIS A CB    1 
ATOM   3396 C CG    . HIS A 1 488 ? 164.309 153.196 137.723 1.00 72.00  ? 488 HIS A CG    1 
ATOM   3397 N ND1   . HIS A 1 488 ? 165.403 152.432 138.070 1.00 71.27  ? 488 HIS A ND1   1 
ATOM   3398 C CD2   . HIS A 1 488 ? 164.765 154.465 137.591 1.00 75.98  ? 488 HIS A CD2   1 
ATOM   3399 C CE1   . HIS A 1 488 ? 166.469 153.208 138.162 1.00 75.95  ? 488 HIS A CE1   1 
ATOM   3400 N NE2   . HIS A 1 488 ? 166.109 154.446 137.877 1.00 79.11  ? 488 HIS A NE2   1 
ATOM   3401 N N     . ARG A 1 489 ? 163.215 151.384 140.926 1.00 56.94  ? 489 ARG A N     1 
ATOM   3402 C CA    . ARG A 1 489 ? 163.825 150.374 141.774 1.00 52.78  ? 489 ARG A CA    1 
ATOM   3403 C C     . ARG A 1 489 ? 162.764 149.389 142.258 1.00 57.12  ? 489 ARG A C     1 
ATOM   3404 O O     . ARG A 1 489 ? 161.561 149.636 142.156 1.00 61.10  ? 489 ARG A O     1 
ATOM   3405 C CB    . ARG A 1 489 ? 164.541 151.023 142.957 1.00 54.31  ? 489 ARG A CB    1 
ATOM   3406 C CG    . ARG A 1 489 ? 165.888 151.622 142.593 1.00 57.42  ? 489 ARG A CG    1 
ATOM   3407 C CD    . ARG A 1 489 ? 166.381 152.579 143.668 1.00 61.63  ? 489 ARG A CD    1 
ATOM   3408 N NE    . ARG A 1 489 ? 166.433 151.947 144.981 1.00 65.37  ? 489 ARG A NE    1 
ATOM   3409 C CZ    . ARG A 1 489 ? 166.217 152.578 146.128 1.00 59.57  ? 489 ARG A CZ    1 
ATOM   3410 N NH1   . ARG A 1 489 ? 165.894 153.861 146.163 1.00 51.24  ? 489 ARG A NH1   1 
ATOM   3411 N NH2   . ARG A 1 489 ? 166.334 151.906 147.270 1.00 62.14  ? 489 ARG A NH2   1 
ATOM   3412 N N     . LYS A 1 490 ? 163.224 148.258 142.786 1.00 49.84  ? 490 LYS A N     1 
ATOM   3413 C CA    . LYS A 1 490 ? 162.310 147.201 143.198 1.00 39.33  ? 490 LYS A CA    1 
ATOM   3414 C C     . LYS A 1 490 ? 161.417 147.658 144.346 1.00 36.63  ? 490 LYS A C     1 
ATOM   3415 O O     . LYS A 1 490 ? 161.863 148.347 145.267 1.00 40.68  ? 490 LYS A O     1 
ATOM   3416 C CB    . LYS A 1 490 ? 163.093 145.955 143.608 1.00 49.45  ? 490 LYS A CB    1 
ATOM   3417 C CG    . LYS A 1 490 ? 163.638 145.143 142.443 1.00 53.11  ? 490 LYS A CG    1 
ATOM   3418 C CD    . LYS A 1 490 ? 162.517 144.692 141.523 1.00 52.20  ? 490 LYS A CD    1 
ATOM   3419 C CE    . LYS A 1 490 ? 162.988 143.635 140.543 1.00 51.80  ? 490 LYS A CE    1 
ATOM   3420 N NZ    . LYS A 1 490 ? 164.144 144.087 139.722 1.00 56.28  ? 490 LYS A NZ    1 
ATOM   3421 N N     . LYS A 1 491 ? 160.139 147.274 144.277 1.00 35.35  ? 491 LYS A N     1 
ATOM   3422 C CA    . LYS A 1 491 ? 159.201 147.607 145.346 1.00 43.46  ? 491 LYS A CA    1 
ATOM   3423 C C     . LYS A 1 491 ? 159.584 146.929 146.655 1.00 48.22  ? 491 LYS A C     1 
ATOM   3424 O O     . LYS A 1 491 ? 159.502 147.544 147.725 1.00 45.82  ? 491 LYS A O     1 
ATOM   3425 C CB    . LYS A 1 491 ? 157.781 147.209 144.949 1.00 44.85  ? 491 LYS A CB    1 
ATOM   3426 C CG    . LYS A 1 491 ? 157.105 148.137 143.960 1.00 48.53  ? 491 LYS A CG    1 
ATOM   3427 C CD    . LYS A 1 491 ? 155.736 147.597 143.565 1.00 51.67  ? 491 LYS A CD    1 
ATOM   3428 C CE    . LYS A 1 491 ? 155.007 148.527 142.612 1.00 58.51  ? 491 LYS A CE    1 
ATOM   3429 N NZ    . LYS A 1 491 ? 153.734 147.936 142.108 1.00 58.56  ? 491 LYS A NZ    1 
ATOM   3430 N N     . ALA A 1 492 ? 159.991 145.658 146.590 1.00 45.11  ? 492 ALA A N     1 
ATOM   3431 C CA    . ALA A 1 492 ? 160.323 144.917 147.803 1.00 36.12  ? 492 ALA A CA    1 
ATOM   3432 C C     . ALA A 1 492 ? 161.503 145.540 148.536 1.00 39.29  ? 492 ALA A C     1 
ATOM   3433 O O     . ALA A 1 492 ? 161.470 145.688 149.762 1.00 44.39  ? 492 ALA A O     1 
ATOM   3434 C CB    . ALA A 1 492 ? 160.613 143.456 147.461 1.00 38.74  ? 492 ALA A CB    1 
ATOM   3435 N N     . GLU A 1 493 ? 162.550 145.924 147.805 1.00 34.73  ? 493 GLU A N     1 
ATOM   3436 C CA    . GLU A 1 493 ? 163.738 146.479 148.448 1.00 36.55  ? 493 GLU A CA    1 
ATOM   3437 C C     . GLU A 1 493 ? 163.454 147.842 149.072 1.00 39.40  ? 493 GLU A C     1 
ATOM   3438 O O     . GLU A 1 493 ? 163.863 148.116 150.210 1.00 43.62  ? 493 GLU A O     1 
ATOM   3439 C CB    . GLU A 1 493 ? 164.878 146.569 147.438 1.00 38.03  ? 493 GLU A CB    1 
ATOM   3440 C CG    . GLU A 1 493 ? 166.165 147.130 148.000 1.00 54.07  ? 493 GLU A CG    1 
ATOM   3441 C CD    . GLU A 1 493 ? 167.289 147.099 146.988 1.00 78.63  ? 493 GLU A CD    1 
ATOM   3442 O OE1   . GLU A 1 493 ? 167.272 146.208 146.113 1.00 86.93  ? 493 GLU A OE1   1 
ATOM   3443 O OE2   . GLU A 1 493 ? 168.185 147.966 147.060 1.00 84.18  ? 493 GLU A OE2   1 
ATOM   3444 N N     . VAL A 1 494 ? 162.755 148.714 148.341 1.00 38.14  ? 494 VAL A N     1 
ATOM   3445 C CA    . VAL A 1 494 ? 162.416 150.029 148.879 1.00 39.99  ? 494 VAL A CA    1 
ATOM   3446 C C     . VAL A 1 494 ? 161.524 149.882 150.101 1.00 36.04  ? 494 VAL A C     1 
ATOM   3447 O O     . VAL A 1 494 ? 161.699 150.575 151.112 1.00 38.24  ? 494 VAL A O     1 
ATOM   3448 C CB    . VAL A 1 494 ? 161.750 150.900 147.799 1.00 45.77  ? 494 VAL A CB    1 
ATOM   3449 C CG1   . VAL A 1 494 ? 161.206 152.173 148.417 1.00 47.65  ? 494 VAL A CG1   1 
ATOM   3450 C CG2   . VAL A 1 494 ? 162.742 151.219 146.695 1.00 53.66  ? 494 VAL A CG2   1 
ATOM   3451 N N     . ALA A 1 495 ? 160.542 148.983 150.018 1.00 35.63  ? 495 ALA A N     1 
ATOM   3452 C CA    . ALA A 1 495 ? 159.649 148.745 151.143 1.00 38.15  ? 495 ALA A CA    1 
ATOM   3453 C C     . ALA A 1 495 ? 160.412 148.222 152.350 1.00 33.81  ? 495 ALA A C     1 
ATOM   3454 O O     . ALA A 1 495 ? 160.134 148.618 153.487 1.00 33.86  ? 495 ALA A O     1 
ATOM   3455 C CB    . ALA A 1 495 ? 158.550 147.768 150.733 1.00 40.11  ? 495 ALA A CB    1 
ATOM   3456 N N     . ALA A 1 496 ? 161.379 147.332 152.124 1.00 33.26  ? 496 ALA A N     1 
ATOM   3457 C CA    . ALA A 1 496 ? 162.193 146.822 153.220 1.00 33.15  ? 496 ALA A CA    1 
ATOM   3458 C C     . ALA A 1 496 ? 162.988 147.940 153.881 1.00 33.45  ? 496 ALA A C     1 
ATOM   3459 O O     . ALA A 1 496 ? 163.030 148.039 155.112 1.00 35.13  ? 496 ALA A O     1 
ATOM   3460 C CB    . ALA A 1 496 ? 163.126 145.723 152.713 1.00 34.88  ? 496 ALA A CB    1 
ATOM   3461 N N     . GLU A 1 497 ? 163.626 148.795 153.077 1.00 35.00  ? 497 GLU A N     1 
ATOM   3462 C CA    . GLU A 1 497 ? 164.399 149.899 153.644 1.00 39.07  ? 497 GLU A CA    1 
ATOM   3463 C C     . GLU A 1 497 ? 163.507 150.849 154.439 1.00 37.50  ? 497 GLU A C     1 
ATOM   3464 O O     . GLU A 1 497 ? 163.866 151.290 155.540 1.00 40.18  ? 497 GLU A O     1 
ATOM   3465 C CB    . GLU A 1 497 ? 165.134 150.656 152.537 1.00 42.07  ? 497 GLU A CB    1 
ATOM   3466 C CG    . GLU A 1 497 ? 166.242 149.869 151.865 1.00 50.40  ? 497 GLU A CG    1 
ATOM   3467 C CD    . GLU A 1 497 ? 167.481 150.708 151.620 1.00 63.92  ? 497 GLU A CD    1 
ATOM   3468 O OE1   . GLU A 1 497 ? 168.076 151.190 152.607 1.00 69.11  ? 497 GLU A OE1   1 
ATOM   3469 O OE2   . GLU A 1 497 ? 167.854 150.893 150.442 1.00 63.87  ? 497 GLU A OE2   1 
ATOM   3470 N N     . ALA A 1 498 ? 162.330 151.168 153.900 1.00 34.34  ? 498 ALA A N     1 
ATOM   3471 C CA    . ALA A 1 498 ? 161.428 152.082 154.593 1.00 34.45  ? 498 ALA A CA    1 
ATOM   3472 C C     . ALA A 1 498 ? 160.895 151.474 155.886 1.00 33.72  ? 498 ALA A C     1 
ATOM   3473 O O     . ALA A 1 498 ? 160.785 152.168 156.905 1.00 37.52  ? 498 ALA A O     1 
ATOM   3474 C CB    . ALA A 1 498 ? 160.285 152.480 153.668 1.00 36.98  ? 498 ALA A CB    1 
ATOM   3475 N N     . THR A 1 499 ? 160.567 150.180 155.872 1.00 30.44  ? 499 THR A N     1 
ATOM   3476 C CA    . THR A 1 499 ? 160.096 149.529 157.089 1.00 25.97  ? 499 THR A CA    1 
ATOM   3477 C C     . THR A 1 499 ? 161.208 149.433 158.127 1.00 25.48  ? 499 THR A C     1 
ATOM   3478 O O     . THR A 1 499 ? 160.948 149.532 159.332 1.00 29.64  ? 499 THR A O     1 
ATOM   3479 C CB    . THR A 1 499 ? 159.533 148.147 156.761 1.00 27.52  ? 499 THR A CB    1 
ATOM   3480 O OG1   . THR A 1 499 ? 158.499 148.277 155.778 1.00 32.18  ? 499 THR A OG1   1 
ATOM   3481 C CG2   . THR A 1 499 ? 158.951 147.502 158.002 1.00 26.42  ? 499 THR A CG2   1 
ATOM   3482 N N     . ARG A 1 500 ? 162.454 149.243 157.684 1.00 21.52  ? 500 ARG A N     1 
ATOM   3483 C CA    . ARG A 1 500 ? 163.577 149.306 158.611 1.00 23.50  ? 500 ARG A CA    1 
ATOM   3484 C C     . ARG A 1 500 ? 163.712 150.692 159.224 1.00 29.85  ? 500 ARG A C     1 
ATOM   3485 O O     . ARG A 1 500 ? 164.047 150.819 160.407 1.00 34.94  ? 500 ARG A O     1 
ATOM   3486 C CB    . ARG A 1 500 ? 164.875 148.917 157.904 1.00 29.22  ? 500 ARG A CB    1 
ATOM   3487 C CG    . ARG A 1 500 ? 164.965 147.457 157.486 1.00 33.89  ? 500 ARG A CG    1 
ATOM   3488 C CD    . ARG A 1 500 ? 166.063 147.271 156.453 1.00 30.35  ? 500 ARG A CD    1 
ATOM   3489 N NE    . ARG A 1 500 ? 166.073 145.936 155.868 1.00 29.65  ? 500 ARG A NE    1 
ATOM   3490 C CZ    . ARG A 1 500 ? 166.868 145.567 154.874 1.00 35.94  ? 500 ARG A CZ    1 
ATOM   3491 N NH1   . ARG A 1 500 ? 167.725 146.411 154.324 1.00 37.44  ? 500 ARG A NH1   1 
ATOM   3492 N NH2   . ARG A 1 500 ? 166.802 144.319 154.419 1.00 39.86  ? 500 ARG A NH2   1 
ATOM   3493 N N     . ARG A 1 501 ? 163.465 151.741 158.437 1.00 33.45  ? 501 ARG A N     1 
ATOM   3494 C CA    . ARG A 1 501 ? 163.515 153.088 158.998 1.00 33.57  ? 501 ARG A CA    1 
ATOM   3495 C C     . ARG A 1 501 ? 162.384 153.330 159.990 1.00 29.14  ? 501 ARG A C     1 
ATOM   3496 O O     . ARG A 1 501 ? 162.579 154.037 160.985 1.00 30.58  ? 501 ARG A O     1 
ATOM   3497 C CB    . ARG A 1 501 ? 163.477 154.133 157.886 1.00 43.20  ? 501 ARG A CB    1 
ATOM   3498 C CG    . ARG A 1 501 ? 164.793 154.301 157.148 1.00 50.83  ? 501 ARG A CG    1 
ATOM   3499 C CD    . ARG A 1 501 ? 164.800 155.566 156.300 1.00 56.12  ? 501 ARG A CD    1 
ATOM   3500 N NE    . ARG A 1 501 ? 163.777 155.556 155.259 1.00 62.47  ? 501 ARG A NE    1 
ATOM   3501 C CZ    . ARG A 1 501 ? 162.622 156.205 155.334 1.00 71.92  ? 501 ARG A CZ    1 
ATOM   3502 N NH1   . ARG A 1 501 ? 162.304 156.931 156.392 1.00 68.26  ? 501 ARG A NH1   1 
ATOM   3503 N NH2   . ARG A 1 501 ? 161.765 156.123 154.320 1.00 79.43  ? 501 ARG A NH2   1 
ATOM   3504 N N     . LEU A 1 502 ? 161.200 152.767 159.738 1.00 30.43  ? 502 LEU A N     1 
ATOM   3505 C CA    . LEU A 1 502 ? 160.115 152.879 160.709 1.00 25.64  ? 502 LEU A CA    1 
ATOM   3506 C C     . LEU A 1 502 ? 160.457 152.163 162.010 1.00 27.47  ? 502 LEU A C     1 
ATOM   3507 O O     . LEU A 1 502 ? 160.128 152.651 163.097 1.00 27.02  ? 502 LEU A O     1 
ATOM   3508 C CB    . LEU A 1 502 ? 158.818 152.322 160.127 1.00 19.79  ? 502 LEU A CB    1 
ATOM   3509 C CG    . LEU A 1 502 ? 158.032 153.202 159.163 1.00 22.56  ? 502 LEU A CG    1 
ATOM   3510 C CD1   . LEU A 1 502 ? 156.761 152.488 158.755 1.00 24.28  ? 502 LEU A CD1   1 
ATOM   3511 C CD2   . LEU A 1 502 ? 157.711 154.543 159.798 1.00 30.88  ? 502 LEU A CD2   1 
ATOM   3512 N N     . ASN A 1 503 ? 161.108 151.005 161.922 1.00 28.10  ? 503 ASN A N     1 
ATOM   3513 C CA    . ASN A 1 503 ? 161.512 150.251 163.105 1.00 21.98  ? 503 ASN A CA    1 
ATOM   3514 C C     . ASN A 1 503 ? 162.737 149.429 162.743 1.00 25.91  ? 503 ASN A C     1 
ATOM   3515 O O     . ASN A 1 503 ? 162.650 148.516 161.916 1.00 33.03  ? 503 ASN A O     1 
ATOM   3516 C CB    . ASN A 1 503 ? 160.380 149.352 163.600 1.00 18.21  ? 503 ASN A CB    1 
ATOM   3517 C CG    . ASN A 1 503 ? 160.706 148.659 164.914 1.00 24.18  ? 503 ASN A CG    1 
ATOM   3518 O OD1   . ASN A 1 503 ? 161.850 148.648 165.362 1.00 22.73  ? 503 ASN A OD1   1 
ATOM   3519 N ND2   . ASN A 1 503 ? 159.691 148.073 165.537 1.00 28.86  ? 503 ASN A ND2   1 
ATOM   3520 N N     . ALA A 1 504 ? 163.874 149.757 163.356 1.00 25.35  ? 504 ALA A N     1 
ATOM   3521 C CA    . ALA A 1 504 ? 165.121 149.065 163.062 1.00 27.00  ? 504 ALA A CA    1 
ATOM   3522 C C     . ALA A 1 504 ? 165.186 147.673 163.674 1.00 34.71  ? 504 ALA A C     1 
ATOM   3523 O O     . ALA A 1 504 ? 166.119 146.925 163.367 1.00 39.56  ? 504 ALA A O     1 
ATOM   3524 C CB    . ALA A 1 504 ? 166.306 149.897 163.549 1.00 26.67  ? 504 ALA A CB    1 
ATOM   3525 N N     . ASP A 1 505 ? 164.227 147.311 164.528 1.00 37.11  ? 505 ASP A N     1 
ATOM   3526 C CA    . ASP A 1 505 ? 164.305 146.036 165.234 1.00 33.79  ? 505 ASP A CA    1 
ATOM   3527 C C     . ASP A 1 505 ? 164.077 144.859 164.293 1.00 33.77  ? 505 ASP A C     1 
ATOM   3528 O O     . ASP A 1 505 ? 164.849 143.894 164.298 1.00 40.81  ? 505 ASP A O     1 
ATOM   3529 C CB    . ASP A 1 505 ? 163.291 146.008 166.379 1.00 36.40  ? 505 ASP A CB    1 
ATOM   3530 C CG    . ASP A 1 505 ? 163.550 147.083 167.418 1.00 48.39  ? 505 ASP A CG    1 
ATOM   3531 O OD1   . ASP A 1 505 ? 164.635 147.701 167.385 1.00 48.40  ? 505 ASP A OD1   1 
ATOM   3532 O OD2   . ASP A 1 505 ? 162.663 147.313 168.267 1.00 48.63  ? 505 ASP A OD2   1 
ATOM   3533 N N     . LEU A 1 506 ? 163.031 144.920 163.473 1.00 26.10  ? 506 LEU A N     1 
ATOM   3534 C CA    . LEU A 1 506 ? 162.603 143.741 162.733 1.00 29.61  ? 506 LEU A CA    1 
ATOM   3535 C C     . LEU A 1 506 ? 163.420 143.542 161.462 1.00 31.50  ? 506 LEU A C     1 
ATOM   3536 O O     . LEU A 1 506 ? 163.880 144.498 160.833 1.00 32.52  ? 506 LEU A O     1 
ATOM   3537 C CB    . LEU A 1 506 ? 161.114 143.820 162.385 1.00 26.63  ? 506 LEU A CB    1 
ATOM   3538 C CG    . LEU A 1 506 ? 160.586 144.900 161.444 1.00 19.68  ? 506 LEU A CG    1 
ATOM   3539 C CD1   . LEU A 1 506 ? 159.282 144.450 160.830 1.00 17.81  ? 506 LEU A CD1   1 
ATOM   3540 C CD2   . LEU A 1 506 ? 160.370 146.182 162.196 1.00 27.17  ? 506 LEU A CD2   1 
ATOM   3541 N N     . GLN A 1 507 ? 163.586 142.273 161.087 1.00 31.55  ? 507 GLN A N     1 
ATOM   3542 C CA    . GLN A 1 507 ? 164.345 141.873 159.902 1.00 29.79  ? 507 GLN A CA    1 
ATOM   3543 C C     . GLN A 1 507 ? 163.369 141.723 158.742 1.00 30.11  ? 507 GLN A C     1 
ATOM   3544 O O     . GLN A 1 507 ? 162.690 140.706 158.604 1.00 34.26  ? 507 GLN A O     1 
ATOM   3545 C CB    . GLN A 1 507 ? 165.111 140.577 160.143 1.00 32.60  ? 507 GLN A CB    1 
ATOM   3546 C CG    . GLN A 1 507 ? 166.440 140.740 160.855 1.00 48.92  ? 507 GLN A CG    1 
ATOM   3547 C CD    . GLN A 1 507 ? 167.312 139.501 160.740 1.00 65.84  ? 507 GLN A CD    1 
ATOM   3548 O OE1   . GLN A 1 507 ? 168.137 139.391 159.832 1.00 70.85  ? 507 GLN A OE1   1 
ATOM   3549 N NE2   . GLN A 1 507 ? 167.132 138.561 161.661 1.00 67.60  ? 507 GLN A NE2   1 
ATOM   3550 N N     . VAL A 1 508 ? 163.301 142.749 157.901 1.00 25.78  ? 508 VAL A N     1 
ATOM   3551 C CA    . VAL A 1 508 ? 162.503 142.701 156.683 1.00 21.56  ? 508 VAL A CA    1 
ATOM   3552 C C     . VAL A 1 508 ? 163.425 142.278 155.546 1.00 28.08  ? 508 VAL A C     1 
ATOM   3553 O O     . VAL A 1 508 ? 164.328 143.021 155.155 1.00 37.13  ? 508 VAL A O     1 
ATOM   3554 C CB    . VAL A 1 508 ? 161.838 144.050 156.393 1.00 20.90  ? 508 VAL A CB    1 
ATOM   3555 C CG1   . VAL A 1 508 ? 160.850 143.916 155.252 1.00 24.13  ? 508 VAL A CG1   1 
ATOM   3556 C CG2   . VAL A 1 508 ? 161.153 144.572 157.637 1.00 24.13  ? 508 VAL A CG2   1 
ATOM   3557 N N     . THR A 1 509 ? 163.198 141.077 155.016 1.00 25.68  ? 509 THR A N     1 
ATOM   3558 C CA    . THR A 1 509 ? 164.017 140.528 153.949 1.00 26.80  ? 509 THR A CA    1 
ATOM   3559 C C     . THR A 1 509 ? 163.303 140.709 152.623 1.00 30.74  ? 509 THR A C     1 
ATOM   3560 O O     . THR A 1 509 ? 162.188 140.187 152.450 1.00 34.39  ? 509 THR A O     1 
ATOM   3561 C CB    . THR A 1 509 ? 164.308 139.052 154.191 1.00 28.68  ? 509 THR A CB    1 
ATOM   3562 O OG1   . THR A 1 509 ? 165.120 138.909 155.363 1.00 32.87  ? 509 THR A OG1   1 
ATOM   3563 C CG2   . THR A 1 509 ? 165.042 138.457 153.001 1.00 33.85  ? 509 THR A CG2   1 
ATOM   3564 N N     . PRO A 1 510 ? 163.879 141.452 151.682 1.00 31.44  ? 510 PRO A N     1 
ATOM   3565 C CA    . PRO A 1 510 ? 163.234 141.617 150.376 1.00 35.27  ? 510 PRO A CA    1 
ATOM   3566 C C     . PRO A 1 510 ? 163.635 140.534 149.388 1.00 45.25  ? 510 PRO A C     1 
ATOM   3567 O O     . PRO A 1 510 ? 164.825 140.304 149.151 1.00 50.73  ? 510 PRO A O     1 
ATOM   3568 C CB    . PRO A 1 510 ? 163.726 142.997 149.929 1.00 38.80  ? 510 PRO A CB    1 
ATOM   3569 C CG    . PRO A 1 510 ? 165.092 143.105 150.541 1.00 34.27  ? 510 PRO A CG    1 
ATOM   3570 C CD    . PRO A 1 510 ? 165.070 142.307 151.826 1.00 31.03  ? 510 PRO A CD    1 
ATOM   3571 N N     . LEU A 1 511 ? 162.650 139.860 148.809 1.00 44.48  ? 511 LEU A N     1 
ATOM   3572 C CA    . LEU A 1 511 ? 162.863 138.924 147.716 1.00 41.28  ? 511 LEU A CA    1 
ATOM   3573 C C     . LEU A 1 511 ? 162.232 139.521 146.470 1.00 46.11  ? 511 LEU A C     1 
ATOM   3574 O O     . LEU A 1 511 ? 161.049 139.876 146.480 1.00 45.10  ? 511 LEU A O     1 
ATOM   3575 C CB    . LEU A 1 511 ? 162.260 137.555 148.030 1.00 41.29  ? 511 LEU A CB    1 
ATOM   3576 C CG    . LEU A 1 511 ? 162.922 136.778 149.165 1.00 45.98  ? 511 LEU A CG    1 
ATOM   3577 C CD1   . LEU A 1 511 ? 162.215 135.451 149.374 1.00 45.66  ? 511 LEU A CD1   1 
ATOM   3578 C CD2   . LEU A 1 511 ? 164.396 136.562 148.872 1.00 50.15  ? 511 LEU A CD2   1 
ATOM   3579 N N     . ASN A 1 512 ? 163.022 139.637 145.401 1.00 50.37  ? 512 ASN A N     1 
ATOM   3580 C CA    . ASN A 1 512 ? 162.577 140.275 144.169 1.00 48.76  ? 512 ASN A CA    1 
ATOM   3581 C C     . ASN A 1 512 ? 161.945 139.290 143.195 1.00 48.51  ? 512 ASN A C     1 
ATOM   3582 O O     . ASN A 1 512 ? 161.976 139.518 141.979 1.00 48.52  ? 512 ASN A O     1 
ATOM   3583 C CB    . ASN A 1 512 ? 163.743 141.009 143.510 1.00 49.58  ? 512 ASN A CB    1 
ATOM   3584 C CG    . ASN A 1 512 ? 164.263 142.152 144.357 1.00 53.96  ? 512 ASN A CG    1 
ATOM   3585 O OD1   . ASN A 1 512 ? 163.512 142.775 145.107 1.00 52.46  ? 512 ASN A OD1   1 
ATOM   3586 N ND2   . ASN A 1 512 ? 165.555 142.434 144.242 1.00 59.06  ? 512 ASN A ND2   1 
ATOM   3587 N N     . LEU A 1 513 ? 161.369 138.204 143.698 1.00 45.42  ? 513 LEU A N     1 
ATOM   3588 C CA    . LEU A 1 513 ? 160.734 137.189 142.875 1.00 42.22  ? 513 LEU A CA    1 
ATOM   3589 C C     . LEU A 1 513 ? 159.262 137.079 143.238 1.00 39.82  ? 513 LEU A C     1 
ATOM   3590 O O     . LEU A 1 513 ? 158.892 137.182 144.410 1.00 42.19  ? 513 LEU A O     1 
ATOM   3591 C CB    . LEU A 1 513 ? 161.416 135.827 143.048 1.00 50.63  ? 513 LEU A CB    1 
ATOM   3592 C CG    . LEU A 1 513 ? 162.798 135.625 142.417 1.00 52.22  ? 513 LEU A CG    1 
ATOM   3593 C CD1   . LEU A 1 513 ? 163.910 136.222 143.271 1.00 46.32  ? 513 LEU A CD1   1 
ATOM   3594 C CD2   . LEU A 1 513 ? 163.051 134.147 142.152 1.00 52.03  ? 513 LEU A CD2   1 
ATOM   3595 N N     . GLN A 1 514 ? 158.424 136.872 142.226 1.00 44.93  ? 514 GLN A N     1 
ATOM   3596 C CA    . GLN A 1 514 ? 157.007 136.657 142.457 1.00 50.59  ? 514 GLN A CA    1 
ATOM   3597 C C     . GLN A 1 514 ? 156.775 135.268 143.058 1.00 57.27  ? 514 GLN A C     1 
ATOM   3598 O O     . GLN A 1 514 ? 157.696 134.459 143.204 1.00 60.63  ? 514 GLN A O     1 
ATOM   3599 C CB    . GLN A 1 514 ? 156.220 136.832 141.155 1.00 55.65  ? 514 GLN A CB    1 
ATOM   3600 C CG    . GLN A 1 514 ? 156.325 135.671 140.175 1.00 62.11  ? 514 GLN A CG    1 
ATOM   3601 C CD    . GLN A 1 514 ? 157.649 135.620 139.434 1.00 67.25  ? 514 GLN A CD    1 
ATOM   3602 O OE1   . GLN A 1 514 ? 158.405 136.590 139.408 1.00 69.99  ? 514 GLN A OE1   1 
ATOM   3603 N NE2   . GLN A 1 514 ? 157.933 134.479 138.820 1.00 63.22  ? 514 GLN A NE2   1 
ATOM   3604 N N     . LEU A 1 515 ? 155.525 134.999 143.429 1.00 57.48  ? 515 LEU A N     1 
ATOM   3605 C CA    . LEU A 1 515 ? 155.126 133.711 143.996 1.00 54.76  ? 515 LEU A CA    1 
ATOM   3606 C C     . LEU A 1 515 ? 154.157 133.045 143.023 1.00 55.55  ? 515 LEU A C     1 
ATOM   3607 O O     . LEU A 1 515 ? 152.968 133.374 142.989 1.00 56.36  ? 515 LEU A O     1 
ATOM   3608 C CB    . LEU A 1 515 ? 154.506 133.882 145.380 1.00 54.16  ? 515 LEU A CB    1 
ATOM   3609 C CG    . LEU A 1 515 ? 154.085 132.593 146.093 1.00 58.46  ? 515 LEU A CG    1 
ATOM   3610 C CD1   . LEU A 1 515 ? 155.192 131.548 146.039 1.00 60.38  ? 515 LEU A CD1   1 
ATOM   3611 C CD2   . LEU A 1 515 ? 153.699 132.877 147.534 1.00 50.82  ? 515 LEU A CD2   1 
ATOM   3612 N N     . ASP A 1 516 ? 154.677 132.114 142.229 1.00 58.46  ? 516 ASP A N     1 
ATOM   3613 C CA    . ASP A 1 516 ? 153.924 131.382 141.218 1.00 60.22  ? 516 ASP A CA    1 
ATOM   3614 C C     . ASP A 1 516 ? 154.602 130.029 141.019 1.00 57.10  ? 516 ASP A C     1 
ATOM   3615 O O     . ASP A 1 516 ? 155.635 129.772 141.650 1.00 58.55  ? 516 ASP A O     1 
ATOM   3616 C CB    . ASP A 1 516 ? 153.841 132.198 139.920 1.00 60.16  ? 516 ASP A CB    1 
ATOM   3617 C CG    . ASP A 1 516 ? 155.202 132.511 139.322 1.00 60.29  ? 516 ASP A CG    1 
ATOM   3618 O OD1   . ASP A 1 516 ? 156.237 132.177 139.935 1.00 60.79  ? 516 ASP A OD1   1 
ATOM   3619 O OD2   . ASP A 1 516 ? 155.232 133.106 138.225 1.00 60.18  ? 516 ASP A OD2   1 
ATOM   3620 N N     . PRO A 1 517 ? 154.061 129.127 140.175 1.00 53.59  ? 517 PRO A N     1 
ATOM   3621 C CA    . PRO A 1 517 ? 154.708 127.818 139.996 1.00 57.21  ? 517 PRO A CA    1 
ATOM   3622 C C     . PRO A 1 517 ? 156.165 127.879 139.563 1.00 50.14  ? 517 PRO A C     1 
ATOM   3623 O O     . PRO A 1 517 ? 156.920 126.934 139.810 1.00 53.81  ? 517 PRO A O     1 
ATOM   3624 C CB    . PRO A 1 517 ? 153.842 127.156 138.918 1.00 61.83  ? 517 PRO A CB    1 
ATOM   3625 C CG    . PRO A 1 517 ? 152.493 127.710 139.157 1.00 54.89  ? 517 PRO A CG    1 
ATOM   3626 C CD    . PRO A 1 517 ? 152.694 129.130 139.617 1.00 48.72  ? 517 PRO A CD    1 
ATOM   3627 N N     . THR A 1 518 ? 156.580 128.969 138.921 1.00 44.65  ? 518 THR A N     1 
ATOM   3628 C CA    . THR A 1 518 ? 157.944 129.059 138.416 1.00 48.03  ? 518 THR A CA    1 
ATOM   3629 C C     . THR A 1 518 ? 158.967 129.394 139.494 1.00 52.79  ? 518 THR A C     1 
ATOM   3630 O O     . THR A 1 518 ? 160.169 129.342 139.216 1.00 54.73  ? 518 THR A O     1 
ATOM   3631 C CB    . THR A 1 518 ? 158.026 130.104 137.301 1.00 58.25  ? 518 THR A CB    1 
ATOM   3632 O OG1   . THR A 1 518 ? 157.926 131.418 137.864 1.00 60.97  ? 518 THR A OG1   1 
ATOM   3633 C CG2   . THR A 1 518 ? 156.897 129.903 136.301 1.00 58.57  ? 518 THR A CG2   1 
ATOM   3634 N N     . THR A 1 519 ? 158.531 129.730 140.709 1.00 58.68  ? 519 THR A N     1 
ATOM   3635 C CA    . THR A 1 519 ? 159.429 130.132 141.787 1.00 59.20  ? 519 THR A CA    1 
ATOM   3636 C C     . THR A 1 519 ? 159.331 129.193 142.985 1.00 59.85  ? 519 THR A C     1 
ATOM   3637 O O     . THR A 1 519 ? 159.506 129.615 144.129 1.00 58.18  ? 519 THR A O     1 
ATOM   3638 C CB    . THR A 1 519 ? 159.145 131.570 142.220 1.00 59.38  ? 519 THR A CB    1 
ATOM   3639 O OG1   . THR A 1 519 ? 157.777 131.685 142.626 1.00 55.78  ? 519 THR A OG1   1 
ATOM   3640 C CG2   . THR A 1 519 ? 159.415 132.534 141.076 1.00 59.19  ? 519 THR A CG2   1 
ATOM   3641 N N     . GLU A 1 520 ? 159.043 127.915 142.734 1.00 59.09  ? 520 GLU A N     1 
ATOM   3642 C CA    . GLU A 1 520 ? 158.931 126.948 143.819 1.00 54.58  ? 520 GLU A CA    1 
ATOM   3643 C C     . GLU A 1 520 ? 160.258 126.703 144.523 1.00 55.01  ? 520 GLU A C     1 
ATOM   3644 O O     . GLU A 1 520 ? 160.259 126.285 145.685 1.00 57.86  ? 520 GLU A O     1 
ATOM   3645 C CB    . GLU A 1 520 ? 158.378 125.627 143.284 1.00 64.73  ? 520 GLU A CB    1 
ATOM   3646 C CG    . GLU A 1 520 ? 156.897 125.664 142.960 1.00 66.47  ? 520 GLU A CG    1 
ATOM   3647 C CD    . GLU A 1 520 ? 156.035 125.566 144.201 1.00 64.86  ? 520 GLU A CD    1 
ATOM   3648 O OE1   . GLU A 1 520 ? 155.896 124.448 144.740 1.00 62.04  ? 520 GLU A OE1   1 
ATOM   3649 O OE2   . GLU A 1 520 ? 155.509 126.607 144.646 1.00 65.77  ? 520 GLU A OE2   1 
ATOM   3650 N N     . ASP A 1 521 ? 161.383 126.947 143.848 1.00 53.96  ? 521 ASP A N     1 
ATOM   3651 C CA    . ASP A 1 521 ? 162.680 126.614 144.428 1.00 52.49  ? 521 ASP A CA    1 
ATOM   3652 C C     . ASP A 1 521 ? 163.012 127.487 145.630 1.00 57.59  ? 521 ASP A C     1 
ATOM   3653 O O     . ASP A 1 521 ? 163.742 127.049 146.526 1.00 62.20  ? 521 ASP A O     1 
ATOM   3654 C CB    . ASP A 1 521 ? 163.779 126.727 143.369 1.00 57.94  ? 521 ASP A CB    1 
ATOM   3655 C CG    . ASP A 1 521 ? 164.029 128.159 142.928 1.00 69.41  ? 521 ASP A CG    1 
ATOM   3656 O OD1   . ASP A 1 521 ? 163.058 128.932 142.795 1.00 67.40  ? 521 ASP A OD1   1 
ATOM   3657 O OD2   . ASP A 1 521 ? 165.207 128.511 142.712 1.00 77.99  ? 521 ASP A OD2   1 
ATOM   3658 N N     . ILE A 1 522 ? 162.494 128.711 145.673 1.00 56.61  ? 522 ILE A N     1 
ATOM   3659 C CA    . ILE A 1 522 ? 162.767 129.614 146.788 1.00 54.63  ? 522 ILE A CA    1 
ATOM   3660 C C     . ILE A 1 522 ? 161.680 129.528 147.850 1.00 51.68  ? 522 ILE A C     1 
ATOM   3661 O O     . ILE A 1 522 ? 161.969 129.359 149.037 1.00 50.45  ? 522 ILE A O     1 
ATOM   3662 C CB    . ILE A 1 522 ? 162.939 131.057 146.271 1.00 55.35  ? 522 ILE A CB    1 
ATOM   3663 C CG1   . ILE A 1 522 ? 164.088 131.125 145.264 1.00 55.62  ? 522 ILE A CG1   1 
ATOM   3664 C CG2   . ILE A 1 522 ? 163.192 132.012 147.425 1.00 52.99  ? 522 ILE A CG2   1 
ATOM   3665 C CD1   . ILE A 1 522 ? 165.405 130.618 145.810 1.00 51.53  ? 522 ILE A CD1   1 
ATOM   3666 N N     . PHE A 1 523 ? 160.419 129.639 147.445 1.00 49.02  ? 523 PHE A N     1 
ATOM   3667 C CA    . PHE A 1 523 ? 159.290 129.512 148.365 1.00 43.35  ? 523 PHE A CA    1 
ATOM   3668 C C     . PHE A 1 523 ? 158.847 128.058 148.497 1.00 43.48  ? 523 PHE A C     1 
ATOM   3669 O O     . PHE A 1 523 ? 157.691 127.710 148.267 1.00 46.73  ? 523 PHE A O     1 
ATOM   3670 C CB    . PHE A 1 523 ? 158.141 130.400 147.903 1.00 43.60  ? 523 PHE A CB    1 
ATOM   3671 C CG    . PHE A 1 523 ? 158.530 131.839 147.712 1.00 47.31  ? 523 PHE A CG    1 
ATOM   3672 C CD1   . PHE A 1 523 ? 158.481 132.732 148.769 1.00 47.53  ? 523 PHE A CD1   1 
ATOM   3673 C CD2   . PHE A 1 523 ? 158.951 132.295 146.477 1.00 49.23  ? 523 PHE A CD2   1 
ATOM   3674 C CE1   . PHE A 1 523 ? 158.844 134.054 148.592 1.00 49.33  ? 523 PHE A CE1   1 
ATOM   3675 C CE2   . PHE A 1 523 ? 159.317 133.613 146.297 1.00 51.52  ? 523 PHE A CE2   1 
ATOM   3676 C CZ    . PHE A 1 523 ? 159.262 134.493 147.354 1.00 50.90  ? 523 PHE A CZ    1 
ATOM   3677 N N     . GLY A 1 524 ? 159.786 127.194 148.868 1.00 46.32  ? 524 GLY A N     1 
ATOM   3678 C CA    . GLY A 1 524 ? 159.529 125.778 149.016 1.00 43.04  ? 524 GLY A CA    1 
ATOM   3679 C C     . GLY A 1 524 ? 159.094 125.406 150.417 1.00 35.59  ? 524 GLY A C     1 
ATOM   3680 O O     . GLY A 1 524 ? 158.545 126.216 151.167 1.00 35.15  ? 524 GLY A O     1 
ATOM   3681 N N     . ASP A 1 525 ? 159.333 124.140 150.764 1.00 35.25  ? 525 ASP A N     1 
ATOM   3682 C CA    . ASP A 1 525 ? 158.994 123.661 152.100 1.00 36.18  ? 525 ASP A CA    1 
ATOM   3683 C C     . ASP A 1 525 ? 159.933 124.242 153.150 1.00 39.16  ? 525 ASP A C     1 
ATOM   3684 O O     . ASP A 1 525 ? 159.496 124.606 154.250 1.00 42.34  ? 525 ASP A O     1 
ATOM   3685 C CB    . ASP A 1 525 ? 159.034 122.133 152.137 1.00 47.82  ? 525 ASP A CB    1 
ATOM   3686 C CG    . ASP A 1 525 ? 158.278 121.496 150.982 1.00 55.04  ? 525 ASP A CG    1 
ATOM   3687 O OD1   . ASP A 1 525 ? 157.291 122.090 150.507 1.00 52.35  ? 525 ASP A OD1   1 
ATOM   3688 O OD2   . ASP A 1 525 ? 158.676 120.393 150.549 1.00 57.38  ? 525 ASP A OD2   1 
ATOM   3689 N N     . ASP A 1 526 ? 161.227 124.326 152.834 1.00 40.03  ? 526 ASP A N     1 
ATOM   3690 C CA    . ASP A 1 526 ? 162.196 124.851 153.791 1.00 42.31  ? 526 ASP A CA    1 
ATOM   3691 C C     . ASP A 1 526 ? 161.943 126.320 154.100 1.00 42.43  ? 526 ASP A C     1 
ATOM   3692 O O     . ASP A 1 526 ? 162.215 126.772 155.218 1.00 43.03  ? 526 ASP A O     1 
ATOM   3693 C CB    . ASP A 1 526 ? 163.618 124.650 153.264 1.00 48.91  ? 526 ASP A CB    1 
ATOM   3694 C CG    . ASP A 1 526 ? 163.876 125.397 151.966 1.00 58.46  ? 526 ASP A CG    1 
ATOM   3695 O OD1   . ASP A 1 526 ? 163.142 125.170 150.981 1.00 61.20  ? 526 ASP A OD1   1 
ATOM   3696 O OD2   . ASP A 1 526 ? 164.816 126.219 151.933 1.00 54.59  ? 526 ASP A OD2   1 
ATOM   3697 N N     . PHE A 1 527 ? 161.436 127.079 153.127 1.00 40.54  ? 527 PHE A N     1 
ATOM   3698 C CA    . PHE A 1 527 ? 161.069 128.468 153.378 1.00 32.78  ? 527 PHE A CA    1 
ATOM   3699 C C     . PHE A 1 527 ? 159.871 128.554 154.312 1.00 32.12  ? 527 PHE A C     1 
ATOM   3700 O O     . PHE A 1 527 ? 159.897 129.290 155.306 1.00 38.31  ? 527 PHE A O     1 
ATOM   3701 C CB    . PHE A 1 527 ? 160.775 129.172 152.052 1.00 34.70  ? 527 PHE A CB    1 
ATOM   3702 C CG    . PHE A 1 527 ? 160.316 130.595 152.200 1.00 38.93  ? 527 PHE A CG    1 
ATOM   3703 C CD1   . PHE A 1 527 ? 161.236 131.622 152.321 1.00 41.99  ? 527 PHE A CD1   1 
ATOM   3704 C CD2   . PHE A 1 527 ? 158.968 130.909 152.191 1.00 36.23  ? 527 PHE A CD2   1 
ATOM   3705 C CE1   . PHE A 1 527 ? 160.822 132.927 152.447 1.00 39.93  ? 527 PHE A CE1   1 
ATOM   3706 C CE2   . PHE A 1 527 ? 158.548 132.213 152.317 1.00 36.16  ? 527 PHE A CE2   1 
ATOM   3707 C CZ    . PHE A 1 527 ? 159.476 133.224 152.447 1.00 40.45  ? 527 PHE A CZ    1 
ATOM   3708 N N     . PHE A 1 528 ? 158.811 127.804 154.014 1.00 29.94  ? 528 PHE A N     1 
ATOM   3709 C CA    . PHE A 1 528 ? 157.610 127.851 154.836 1.00 30.31  ? 528 PHE A CA    1 
ATOM   3710 C C     . PHE A 1 528 ? 157.779 127.173 156.187 1.00 35.03  ? 528 PHE A C     1 
ATOM   3711 O O     . PHE A 1 528 ? 156.887 127.297 157.031 1.00 40.72  ? 528 PHE A O     1 
ATOM   3712 C CB    . PHE A 1 528 ? 156.432 127.227 154.091 1.00 26.24  ? 528 PHE A CB    1 
ATOM   3713 C CG    . PHE A 1 528 ? 155.709 128.188 153.197 1.00 26.48  ? 528 PHE A CG    1 
ATOM   3714 C CD1   . PHE A 1 528 ? 154.645 128.936 153.675 1.00 29.71  ? 528 PHE A CD1   1 
ATOM   3715 C CD2   . PHE A 1 528 ? 156.095 128.351 151.880 1.00 29.44  ? 528 PHE A CD2   1 
ATOM   3716 C CE1   . PHE A 1 528 ? 153.979 129.821 152.854 1.00 29.73  ? 528 PHE A CE1   1 
ATOM   3717 C CE2   . PHE A 1 528 ? 155.432 129.237 151.056 1.00 27.65  ? 528 PHE A CE2   1 
ATOM   3718 C CZ    . PHE A 1 528 ? 154.374 129.972 151.544 1.00 26.68  ? 528 PHE A CZ    1 
ATOM   3719 N N     . SER A 1 529 ? 158.885 126.463 156.415 1.00 33.20  ? 529 SER A N     1 
ATOM   3720 C CA    . SER A 1 529 ? 159.086 125.840 157.718 1.00 31.41  ? 529 SER A CA    1 
ATOM   3721 C C     . SER A 1 529 ? 159.175 126.888 158.822 1.00 37.09  ? 529 SER A C     1 
ATOM   3722 O O     . SER A 1 529 ? 158.676 126.672 159.932 1.00 39.28  ? 529 SER A O     1 
ATOM   3723 C CB    . SER A 1 529 ? 160.343 124.975 157.701 1.00 30.80  ? 529 SER A CB    1 
ATOM   3724 O OG    . SER A 1 529 ? 161.506 125.780 157.732 1.00 34.65  ? 529 SER A OG    1 
ATOM   3725 N N     . GLY A 1 530 ? 159.808 128.024 158.537 1.00 37.52  ? 530 GLY A N     1 
ATOM   3726 C CA    . GLY A 1 530 ? 159.903 129.108 159.495 1.00 38.82  ? 530 GLY A CA    1 
ATOM   3727 C C     . GLY A 1 530 ? 158.762 130.103 159.413 1.00 33.56  ? 530 GLY A C     1 
ATOM   3728 O O     . GLY A 1 530 ? 158.534 130.876 160.349 1.00 33.96  ? 530 GLY A O     1 
ATOM   3729 N N     . VAL A 1 531 ? 158.036 130.093 158.296 1.00 29.11  ? 531 VAL A N     1 
ATOM   3730 C CA    . VAL A 1 531 ? 156.962 131.056 158.089 1.00 26.07  ? 531 VAL A CA    1 
ATOM   3731 C C     . VAL A 1 531 ? 155.759 130.671 158.938 1.00 29.41  ? 531 VAL A C     1 
ATOM   3732 O O     . VAL A 1 531 ? 155.274 129.534 158.882 1.00 34.70  ? 531 VAL A O     1 
ATOM   3733 C CB    . VAL A 1 531 ? 156.597 131.139 156.601 1.00 29.35  ? 531 VAL A CB    1 
ATOM   3734 C CG1   . VAL A 1 531 ? 155.388 132.033 156.400 1.00 27.59  ? 531 VAL A CG1   1 
ATOM   3735 C CG2   . VAL A 1 531 ? 157.776 131.656 155.803 1.00 35.05  ? 531 VAL A CG2   1 
ATOM   3736 N N     . ASN A 1 532 ? 155.276 131.621 159.735 1.00 25.93  ? 532 ASN A N     1 
ATOM   3737 C CA    . ASN A 1 532 ? 154.124 131.410 160.596 1.00 22.38  ? 532 ASN A CA    1 
ATOM   3738 C C     . ASN A 1 532 ? 152.804 131.771 159.929 1.00 21.21  ? 532 ASN A C     1 
ATOM   3739 O O     . ASN A 1 532 ? 151.754 131.294 160.371 1.00 25.61  ? 532 ASN A O     1 
ATOM   3740 C CB    . ASN A 1 532 ? 154.285 132.219 161.888 1.00 19.75  ? 532 ASN A CB    1 
ATOM   3741 C CG    . ASN A 1 532 ? 155.473 131.769 162.714 1.00 24.15  ? 532 ASN A CG    1 
ATOM   3742 O OD1   . ASN A 1 532 ? 156.452 132.495 162.864 1.00 23.05  ? 532 ASN A OD1   1 
ATOM   3743 N ND2   . ASN A 1 532 ? 155.392 130.563 163.260 1.00 32.51  ? 532 ASN A ND2   1 
ATOM   3744 N N     . GLY A 1 533 ? 152.829 132.586 158.882 1.00 19.40  ? 533 GLY A N     1 
ATOM   3745 C CA    . GLY A 1 533 ? 151.602 132.979 158.211 1.00 24.26  ? 533 GLY A CA    1 
ATOM   3746 C C     . GLY A 1 533 ? 151.917 133.856 157.020 1.00 26.36  ? 533 GLY A C     1 
ATOM   3747 O O     . GLY A 1 533 ? 153.049 134.324 156.844 1.00 30.51  ? 533 GLY A O     1 
ATOM   3748 N N     . VAL A 1 534 ? 150.891 134.075 156.198 1.00 24.95  ? 534 VAL A N     1 
ATOM   3749 C CA    . VAL A 1 534 ? 151.036 134.795 154.936 1.00 27.84  ? 534 VAL A CA    1 
ATOM   3750 C C     . VAL A 1 534 ? 150.024 135.931 154.885 1.00 32.29  ? 534 VAL A C     1 
ATOM   3751 O O     . VAL A 1 534 ? 148.846 135.733 155.199 1.00 31.85  ? 534 VAL A O     1 
ATOM   3752 C CB    . VAL A 1 534 ? 150.862 133.860 153.727 1.00 29.31  ? 534 VAL A CB    1 
ATOM   3753 C CG1   . VAL A 1 534 ? 150.972 134.644 152.434 1.00 30.13  ? 534 VAL A CG1   1 
ATOM   3754 C CG2   . VAL A 1 534 ? 151.894 132.750 153.766 1.00 28.07  ? 534 VAL A CG2   1 
ATOM   3755 N N     . ALA A 1 535 ? 150.494 137.118 154.506 1.00 36.66  ? 535 ALA A N     1 
ATOM   3756 C CA    . ALA A 1 535 ? 149.649 138.276 154.241 1.00 30.83  ? 535 ALA A CA    1 
ATOM   3757 C C     . ALA A 1 535 ? 149.697 138.602 152.754 1.00 35.43  ? 535 ALA A C     1 
ATOM   3758 O O     . ALA A 1 535 ? 150.774 138.853 152.202 1.00 40.10  ? 535 ALA A O     1 
ATOM   3759 C CB    . ALA A 1 535 ? 150.095 139.483 155.067 1.00 30.52  ? 535 ALA A CB    1 
ATOM   3760 N N     . ALA A 1 536 ? 148.525 138.647 152.126 1.00 42.54  ? 536 ALA A N     1 
ATOM   3761 C CA    . ALA A 1 536 ? 148.382 138.706 150.680 1.00 46.17  ? 536 ALA A CA    1 
ATOM   3762 C C     . ALA A 1 536 ? 147.791 140.051 150.285 1.00 49.54  ? 536 ALA A C     1 
ATOM   3763 O O     . ALA A 1 536 ? 146.701 140.414 150.742 1.00 55.51  ? 536 ALA A O     1 
ATOM   3764 C CB    . ALA A 1 536 ? 147.495 137.564 150.182 1.00 41.56  ? 536 ALA A CB    1 
ATOM   3765 N N     . ALA A 1 537 ? 148.522 140.785 149.447 1.00 45.60  ? 537 ALA A N     1 
ATOM   3766 C CA    . ALA A 1 537 ? 148.078 142.054 148.878 1.00 51.61  ? 537 ALA A CA    1 
ATOM   3767 C C     . ALA A 1 537 ? 148.238 142.000 147.355 1.00 53.26  ? 537 ALA A C     1 
ATOM   3768 O O     . ALA A 1 537 ? 148.783 142.906 146.726 1.00 59.02  ? 537 ALA A O     1 
ATOM   3769 C CB    . ALA A 1 537 ? 148.846 143.227 149.482 1.00 56.65  ? 537 ALA A CB    1 
ATOM   3770 N N     . LEU A 1 538 ? 147.761 140.911 146.759 1.00 51.04  ? 538 LEU A N     1 
ATOM   3771 C CA    . LEU A 1 538 ? 147.979 140.656 145.343 1.00 61.32  ? 538 LEU A CA    1 
ATOM   3772 C C     . LEU A 1 538 ? 147.129 141.578 144.473 1.00 65.87  ? 538 LEU A C     1 
ATOM   3773 O O     . LEU A 1 538 ? 146.167 142.200 144.929 1.00 69.32  ? 538 LEU A O     1 
ATOM   3774 C CB    . LEU A 1 538 ? 147.662 139.202 144.997 1.00 60.29  ? 538 LEU A CB    1 
ATOM   3775 C CG    . LEU A 1 538 ? 148.682 138.138 145.399 1.00 59.55  ? 538 LEU A CG    1 
ATOM   3776 C CD1   . LEU A 1 538 ? 150.088 138.673 145.224 1.00 57.41  ? 538 LEU A CD1   1 
ATOM   3777 C CD2   . LEU A 1 538 ? 148.451 137.658 146.810 1.00 50.67  ? 538 LEU A CD2   1 
ATOM   3778 N N     . ASP A 1 539 ? 147.509 141.663 143.198 1.00 57.31  ? 539 ASP A N     1 
ATOM   3779 C CA    . ASP A 1 539 ? 146.800 142.478 142.220 1.00 57.07  ? 539 ASP A CA    1 
ATOM   3780 C C     . ASP A 1 539 ? 145.844 141.681 141.339 1.00 64.29  ? 539 ASP A C     1 
ATOM   3781 O O     . ASP A 1 539 ? 145.199 142.275 140.469 1.00 66.97  ? 539 ASP A O     1 
ATOM   3782 C CB    . ASP A 1 539 ? 147.798 143.231 141.329 1.00 66.78  ? 539 ASP A CB    1 
ATOM   3783 C CG    . ASP A 1 539 ? 148.594 142.308 140.418 1.00 68.06  ? 539 ASP A CG    1 
ATOM   3784 O OD1   . ASP A 1 539 ? 148.569 141.077 140.623 1.00 68.58  ? 539 ASP A OD1   1 
ATOM   3785 O OD2   . ASP A 1 539 ? 149.249 142.823 139.487 1.00 68.64  ? 539 ASP A OD2   1 
ATOM   3786 N N     . THR A 1 540 ? 145.735 140.367 141.529 1.00 61.23  ? 540 THR A N     1 
ATOM   3787 C CA    . THR A 1 540 ? 144.948 139.531 140.632 1.00 53.84  ? 540 THR A CA    1 
ATOM   3788 C C     . THR A 1 540 ? 144.315 138.386 141.408 1.00 51.14  ? 540 THR A C     1 
ATOM   3789 O O     . THR A 1 540 ? 144.808 137.982 142.464 1.00 55.09  ? 540 THR A O     1 
ATOM   3790 C CB    . THR A 1 540 ? 145.794 138.955 139.487 1.00 50.35  ? 540 THR A CB    1 
ATOM   3791 O OG1   . THR A 1 540 ? 147.052 138.501 140.000 1.00 57.87  ? 540 THR A OG1   1 
ATOM   3792 C CG2   . THR A 1 540 ? 146.033 139.994 138.400 1.00 47.98  ? 540 THR A CG2   1 
ATOM   3793 N N     . PHE A 1 541 ? 143.205 137.875 140.870 1.00 47.29  ? 541 PHE A N     1 
ATOM   3794 C CA    . PHE A 1 541 ? 142.559 136.712 141.466 1.00 42.11  ? 541 PHE A CA    1 
ATOM   3795 C C     . PHE A 1 541 ? 143.407 135.451 141.317 1.00 44.41  ? 541 PHE A C     1 
ATOM   3796 O O     . PHE A 1 541 ? 143.332 134.556 142.166 1.00 51.26  ? 541 PHE A O     1 
ATOM   3797 C CB    . PHE A 1 541 ? 141.184 136.486 140.838 1.00 45.36  ? 541 PHE A CB    1 
ATOM   3798 C CG    . PHE A 1 541 ? 140.223 137.631 141.012 1.00 49.77  ? 541 PHE A CG    1 
ATOM   3799 C CD1   . PHE A 1 541 ? 139.593 137.848 142.224 1.00 55.18  ? 541 PHE A CD1   1 
ATOM   3800 C CD2   . PHE A 1 541 ? 139.917 138.463 139.946 1.00 50.15  ? 541 PHE A CD2   1 
ATOM   3801 C CE1   . PHE A 1 541 ? 138.692 138.879 142.377 1.00 57.64  ? 541 PHE A CE1   1 
ATOM   3802 C CE2   . PHE A 1 541 ? 139.018 139.500 140.092 1.00 53.32  ? 541 PHE A CE2   1 
ATOM   3803 C CZ    . PHE A 1 541 ? 138.403 139.707 141.310 1.00 54.29  ? 541 PHE A CZ    1 
ATOM   3804 N N     . GLU A 1 542 ? 144.209 135.354 140.251 1.00 45.50  ? 542 GLU A N     1 
ATOM   3805 C CA    . GLU A 1 542 ? 144.983 134.136 140.011 1.00 51.55  ? 542 GLU A CA    1 
ATOM   3806 C C     . GLU A 1 542 ? 146.128 133.990 141.007 1.00 49.47  ? 542 GLU A C     1 
ATOM   3807 O O     . GLU A 1 542 ? 146.381 132.890 141.518 1.00 50.26  ? 542 GLU A O     1 
ATOM   3808 C CB    . GLU A 1 542 ? 145.515 134.124 138.577 1.00 54.49  ? 542 GLU A CB    1 
ATOM   3809 C CG    . GLU A 1 542 ? 146.187 132.817 138.173 1.00 63.27  ? 542 GLU A CG    1 
ATOM   3810 C CD    . GLU A 1 542 ? 147.692 132.943 138.059 1.00 66.32  ? 542 GLU A CD    1 
ATOM   3811 O OE1   . GLU A 1 542 ? 148.232 133.985 138.483 1.00 64.48  ? 542 GLU A OE1   1 
ATOM   3812 O OE2   . GLU A 1 542 ? 148.333 132.006 137.539 1.00 71.34  ? 542 GLU A OE2   1 
ATOM   3813 N N     . ALA A 1 543 ? 146.832 135.086 141.296 1.00 48.30  ? 543 ALA A N     1 
ATOM   3814 C CA    . ALA A 1 543 ? 147.873 135.043 142.317 1.00 49.34  ? 543 ALA A CA    1 
ATOM   3815 C C     . ALA A 1 543 ? 147.279 134.755 143.690 1.00 46.12  ? 543 ALA A C     1 
ATOM   3816 O O     . ALA A 1 543 ? 147.873 134.017 144.487 1.00 46.03  ? 543 ALA A O     1 
ATOM   3817 C CB    . ALA A 1 543 ? 148.656 136.354 142.322 1.00 49.34  ? 543 ALA A CB    1 
ATOM   3818 N N     . ARG A 1 544 ? 146.108 135.324 143.981 1.00 46.17  ? 544 ARG A N     1 
ATOM   3819 C CA    . ARG A 1 544 ? 145.415 134.990 145.220 1.00 42.97  ? 544 ARG A CA    1 
ATOM   3820 C C     . ARG A 1 544 ? 145.086 133.507 145.287 1.00 43.25  ? 544 ARG A C     1 
ATOM   3821 O O     . ARG A 1 544 ? 145.261 132.873 146.331 1.00 41.41  ? 544 ARG A O     1 
ATOM   3822 C CB    . ARG A 1 544 ? 144.141 135.814 145.351 1.00 41.13  ? 544 ARG A CB    1 
ATOM   3823 C CG    . ARG A 1 544 ? 144.405 137.271 145.567 1.00 45.03  ? 544 ARG A CG    1 
ATOM   3824 C CD    . ARG A 1 544 ? 143.121 138.055 145.620 1.00 48.45  ? 544 ARG A CD    1 
ATOM   3825 N NE    . ARG A 1 544 ? 143.389 139.484 145.558 1.00 55.70  ? 544 ARG A NE    1 
ATOM   3826 C CZ    . ARG A 1 544 ? 143.681 140.232 146.612 1.00 59.92  ? 544 ARG A CZ    1 
ATOM   3827 N NH1   . ARG A 1 544 ? 143.712 139.725 147.832 1.00 56.59  ? 544 ARG A NH1   1 
ATOM   3828 N NH2   . ARG A 1 544 ? 143.956 141.518 146.437 1.00 57.88  ? 544 ARG A NH2   1 
ATOM   3829 N N     . ASP A 1 545 ? 144.603 132.940 144.183 1.00 47.26  ? 545 ASP A N     1 
ATOM   3830 C CA    . ASP A 1 545 ? 144.283 131.519 144.168 1.00 44.27  ? 545 ASP A CA    1 
ATOM   3831 C C     . ASP A 1 545 ? 145.526 130.676 144.418 1.00 40.29  ? 545 ASP A C     1 
ATOM   3832 O O     . ASP A 1 545 ? 145.482 129.702 145.178 1.00 46.56  ? 545 ASP A O     1 
ATOM   3833 C CB    . ASP A 1 545 ? 143.632 131.144 142.839 1.00 46.66  ? 545 ASP A CB    1 
ATOM   3834 C CG    . ASP A 1 545 ? 143.341 129.666 142.732 1.00 53.51  ? 545 ASP A CG    1 
ATOM   3835 O OD1   . ASP A 1 545 ? 142.541 129.161 143.547 1.00 52.46  ? 545 ASP A OD1   1 
ATOM   3836 O OD2   . ASP A 1 545 ? 143.912 129.012 141.835 1.00 59.16  ? 545 ASP A OD2   1 
ATOM   3837 N N     . TYR A 1 546 ? 146.648 131.040 143.796 1.00 36.98  ? 546 TYR A N     1 
ATOM   3838 C CA    . TYR A 1 546 ? 147.870 130.265 143.990 1.00 35.63  ? 546 TYR A CA    1 
ATOM   3839 C C     . TYR A 1 546 ? 148.366 130.357 145.426 1.00 41.40  ? 546 TYR A C     1 
ATOM   3840 O O     . TYR A 1 546 ? 148.752 129.345 146.026 1.00 48.54  ? 546 TYR A O     1 
ATOM   3841 C CB    . TYR A 1 546 ? 148.961 130.718 143.028 1.00 37.32  ? 546 TYR A CB    1 
ATOM   3842 C CG    . TYR A 1 546 ? 150.140 129.780 143.019 1.00 46.14  ? 546 TYR A CG    1 
ATOM   3843 C CD1   . TYR A 1 546 ? 150.058 128.547 142.388 1.00 60.61  ? 546 TYR A CD1   1 
ATOM   3844 C CD2   . TYR A 1 546 ? 151.333 130.119 143.642 1.00 43.25  ? 546 TYR A CD2   1 
ATOM   3845 C CE1   . TYR A 1 546 ? 151.126 127.679 142.376 1.00 62.10  ? 546 TYR A CE1   1 
ATOM   3846 C CE2   . TYR A 1 546 ? 152.410 129.256 143.632 1.00 48.67  ? 546 TYR A CE2   1 
ATOM   3847 C CZ    . TYR A 1 546 ? 152.299 128.038 142.996 1.00 60.91  ? 546 TYR A CZ    1 
ATOM   3848 O OH    . TYR A 1 546 ? 153.360 127.166 142.974 1.00 63.52  ? 546 TYR A OH    1 
ATOM   3849 N N     . VAL A 1 547 ? 148.398 131.568 145.989 1.00 42.45  ? 547 VAL A N     1 
ATOM   3850 C CA    . VAL A 1 547 ? 148.882 131.708 147.360 1.00 35.91  ? 547 VAL A CA    1 
ATOM   3851 C C     . VAL A 1 547 ? 147.938 131.021 148.337 1.00 30.43  ? 547 VAL A C     1 
ATOM   3852 O O     . VAL A 1 547 ? 148.383 130.462 149.341 1.00 32.53  ? 547 VAL A O     1 
ATOM   3853 C CB    . VAL A 1 547 ? 149.114 133.189 147.727 1.00 42.87  ? 547 VAL A CB    1 
ATOM   3854 C CG1   . VAL A 1 547 ? 150.131 133.819 146.782 1.00 42.73  ? 547 VAL A CG1   1 
ATOM   3855 C CG2   . VAL A 1 547 ? 147.813 133.971 147.735 1.00 45.98  ? 547 VAL A CG2   1 
ATOM   3856 N N     . ALA A 1 548 ? 146.631 131.031 148.062 1.00 30.62  ? 548 ALA A N     1 
ATOM   3857 C CA    . ALA A 1 548 ? 145.694 130.311 148.918 1.00 30.34  ? 548 ALA A CA    1 
ATOM   3858 C C     . ALA A 1 548 ? 145.908 128.808 148.826 1.00 28.69  ? 548 ALA A C     1 
ATOM   3859 O O     . ALA A 1 548 ? 145.811 128.100 149.834 1.00 33.06  ? 548 ALA A O     1 
ATOM   3860 C CB    . ALA A 1 548 ? 144.258 130.670 148.550 1.00 33.25  ? 548 ALA A CB    1 
ATOM   3861 N N     . ALA A 1 549 ? 146.195 128.300 147.626 1.00 28.42  ? 549 ALA A N     1 
ATOM   3862 C CA    . ALA A 1 549 ? 146.503 126.882 147.483 1.00 28.97  ? 549 ALA A CA    1 
ATOM   3863 C C     . ALA A 1 549 ? 147.768 126.515 148.249 1.00 29.50  ? 549 ALA A C     1 
ATOM   3864 O O     . ALA A 1 549 ? 147.820 125.475 148.915 1.00 32.34  ? 549 ALA A O     1 
ATOM   3865 C CB    . ALA A 1 549 ? 146.644 126.523 146.005 1.00 29.69  ? 549 ALA A CB    1 
ATOM   3866 N N     . ARG A 1 550 ? 148.798 127.360 148.171 1.00 26.74  ? 550 ARG A N     1 
ATOM   3867 C CA    . ARG A 1 550 ? 150.024 127.105 148.924 1.00 26.28  ? 550 ARG A CA    1 
ATOM   3868 C C     . ARG A 1 550 ? 149.781 127.179 150.428 1.00 30.76  ? 550 ARG A C     1 
ATOM   3869 O O     . ARG A 1 550 ? 150.350 126.395 151.196 1.00 32.08  ? 550 ARG A O     1 
ATOM   3870 C CB    . ARG A 1 550 ? 151.111 128.092 148.506 1.00 24.91  ? 550 ARG A CB    1 
ATOM   3871 C CG    . ARG A 1 550 ? 151.479 128.009 147.043 1.00 33.75  ? 550 ARG A CG    1 
ATOM   3872 C CD    . ARG A 1 550 ? 151.959 126.618 146.676 1.00 37.02  ? 550 ARG A CD    1 
ATOM   3873 N NE    . ARG A 1 550 ? 153.295 126.344 147.189 1.00 40.09  ? 550 ARG A NE    1 
ATOM   3874 C CZ    . ARG A 1 550 ? 153.940 125.198 147.023 1.00 41.62  ? 550 ARG A CZ    1 
ATOM   3875 N NH1   . ARG A 1 550 ? 153.393 124.185 146.372 1.00 38.90  ? 550 ARG A NH1   1 
ATOM   3876 N NH2   . ARG A 1 550 ? 155.166 125.065 147.520 1.00 45.29  ? 550 ARG A NH2   1 
ATOM   3877 N N     . CYS A 1 551 ? 148.950 128.126 150.866 1.00 29.02  ? 551 CYS A N     1 
ATOM   3878 C CA    . CYS A 1 551 ? 148.619 128.236 152.282 1.00 26.04  ? 551 CYS A CA    1 
ATOM   3879 C C     . CYS A 1 551 ? 147.855 127.012 152.767 1.00 27.33  ? 551 CYS A C     1 
ATOM   3880 O O     . CYS A 1 551 ? 148.084 126.530 153.882 1.00 29.00  ? 551 CYS A O     1 
ATOM   3881 C CB    . CYS A 1 551 ? 147.812 129.511 152.527 1.00 23.22  ? 551 CYS A CB    1 
ATOM   3882 S SG    . CYS A 1 551 ? 148.759 131.031 152.332 1.00 37.08  ? 551 CYS A SG    1 
ATOM   3883 N N     . THR A 1 552 ? 146.934 126.504 151.948 1.00 26.02  ? 552 THR A N     1 
ATOM   3884 C CA    . THR A 1 552 ? 146.248 125.262 152.284 1.00 23.55  ? 552 THR A CA    1 
ATOM   3885 C C     . THR A 1 552 ? 147.231 124.102 152.343 1.00 24.29  ? 552 THR A C     1 
ATOM   3886 O O     . THR A 1 552 ? 147.143 123.247 153.231 1.00 27.06  ? 552 THR A O     1 
ATOM   3887 C CB    . THR A 1 552 ? 145.142 124.979 151.267 1.00 22.45  ? 552 THR A CB    1 
ATOM   3888 O OG1   . THR A 1 552 ? 144.215 126.070 151.248 1.00 26.94  ? 552 THR A OG1   1 
ATOM   3889 C CG2   . THR A 1 552 ? 144.398 123.709 151.628 1.00 25.32  ? 552 THR A CG2   1 
ATOM   3890 N N     . HIS A 1 553 ? 148.182 124.066 151.408 1.00 22.61  ? 553 HIS A N     1 
ATOM   3891 C CA    . HIS A 1 553 ? 149.165 122.991 151.377 1.00 21.79  ? 553 HIS A CA    1 
ATOM   3892 C C     . HIS A 1 553 ? 150.038 122.990 152.624 1.00 25.16  ? 553 HIS A C     1 
ATOM   3893 O O     . HIS A 1 553 ? 150.319 121.929 153.191 1.00 26.69  ? 553 HIS A O     1 
ATOM   3894 C CB    . HIS A 1 553 ? 150.028 123.118 150.122 1.00 23.32  ? 553 HIS A CB    1 
ATOM   3895 C CG    . HIS A 1 553 ? 151.226 122.222 150.118 1.00 28.10  ? 553 HIS A CG    1 
ATOM   3896 N ND1   . HIS A 1 553 ? 151.141 120.865 150.336 1.00 31.56  ? 553 HIS A ND1   1 
ATOM   3897 C CD2   . HIS A 1 553 ? 152.537 122.489 149.915 1.00 32.31  ? 553 HIS A CD2   1 
ATOM   3898 C CE1   . HIS A 1 553 ? 152.349 120.335 150.273 1.00 35.36  ? 553 HIS A CE1   1 
ATOM   3899 N NE2   . HIS A 1 553 ? 153.215 121.298 150.017 1.00 35.01  ? 553 HIS A NE2   1 
ATOM   3900 N N     . PHE A 1 554 ? 150.485 124.161 153.060 1.00 25.63  ? 554 PHE A N     1 
ATOM   3901 C CA    . PHE A 1 554 ? 151.418 124.255 154.174 1.00 22.17  ? 554 PHE A CA    1 
ATOM   3902 C C     . PHE A 1 554 ? 150.738 124.486 155.513 1.00 21.43  ? 554 PHE A C     1 
ATOM   3903 O O     . PHE A 1 554 ? 151.432 124.585 156.530 1.00 23.83  ? 554 PHE A O     1 
ATOM   3904 C CB    . PHE A 1 554 ? 152.428 125.370 153.917 1.00 21.56  ? 554 PHE A CB    1 
ATOM   3905 C CG    . PHE A 1 554 ? 153.405 125.054 152.835 1.00 23.25  ? 554 PHE A CG    1 
ATOM   3906 C CD1   . PHE A 1 554 ? 154.388 124.106 153.037 1.00 23.06  ? 554 PHE A CD1   1 
ATOM   3907 C CD2   . PHE A 1 554 ? 153.347 125.704 151.618 1.00 24.26  ? 554 PHE A CD2   1 
ATOM   3908 C CE1   . PHE A 1 554 ? 155.291 123.810 152.046 1.00 28.17  ? 554 PHE A CE1   1 
ATOM   3909 C CE2   . PHE A 1 554 ? 154.249 125.413 150.624 1.00 27.69  ? 554 PHE A CE2   1 
ATOM   3910 C CZ    . PHE A 1 554 ? 155.223 124.463 150.837 1.00 31.38  ? 554 PHE A CZ    1 
ATOM   3911 N N     . LEU A 1 555 ? 149.409 124.563 155.538 1.00 20.95  ? 555 LEU A N     1 
ATOM   3912 C CA    . LEU A 1 555 ? 148.651 124.845 156.754 1.00 20.36  ? 555 LEU A CA    1 
ATOM   3913 C C     . LEU A 1 555 ? 149.116 126.148 157.400 1.00 21.22  ? 555 LEU A C     1 
ATOM   3914 O O     . LEU A 1 555 ? 149.406 126.211 158.595 1.00 24.10  ? 555 LEU A O     1 
ATOM   3915 C CB    . LEU A 1 555 ? 148.735 123.678 157.740 1.00 25.69  ? 555 LEU A CB    1 
ATOM   3916 C CG    . LEU A 1 555 ? 148.195 122.340 157.231 1.00 25.92  ? 555 LEU A CG    1 
ATOM   3917 C CD1   . LEU A 1 555 ? 148.363 121.256 158.285 1.00 26.71  ? 555 LEU A CD1   1 
ATOM   3918 C CD2   . LEU A 1 555 ? 146.743 122.472 156.818 1.00 20.69  ? 555 LEU A CD2   1 
ATOM   3919 N N     . LYS A 1 556 ? 149.185 127.201 156.589 1.00 19.78  ? 556 LYS A N     1 
ATOM   3920 C CA    . LYS A 1 556 ? 149.574 128.519 157.058 1.00 19.13  ? 556 LYS A CA    1 
ATOM   3921 C C     . LYS A 1 556 ? 148.369 129.442 157.058 1.00 21.59  ? 556 LYS A C     1 
ATOM   3922 O O     . LYS A 1 556 ? 147.630 129.479 156.066 1.00 25.48  ? 556 LYS A O     1 
ATOM   3923 C CB    . LYS A 1 556 ? 150.673 129.108 156.172 1.00 19.36  ? 556 LYS A CB    1 
ATOM   3924 C CG    . LYS A 1 556 ? 151.929 128.268 156.101 1.00 22.33  ? 556 LYS A CG    1 
ATOM   3925 C CD    . LYS A 1 556 ? 152.553 128.093 157.469 1.00 19.01  ? 556 LYS A CD    1 
ATOM   3926 C CE    . LYS A 1 556 ? 153.690 127.096 157.418 1.00 22.75  ? 556 LYS A CE    1 
ATOM   3927 N NZ    . LYS A 1 556 ? 154.286 126.858 158.753 1.00 25.12  ? 556 LYS A NZ    1 
ATOM   3928 N N     . PRO A 1 557 ? 148.124 130.179 158.140 1.00 17.01  ? 557 PRO A N     1 
ATOM   3929 C CA    . PRO A 1 557 ? 147.032 131.161 158.130 1.00 20.31  ? 557 PRO A CA    1 
ATOM   3930 C C     . PRO A 1 557 ? 147.274 132.224 157.071 1.00 29.42  ? 557 PRO A C     1 
ATOM   3931 O O     . PRO A 1 557 ? 148.320 132.884 157.049 1.00 35.82  ? 557 PRO A O     1 
ATOM   3932 C CB    . PRO A 1 557 ? 147.070 131.745 159.548 1.00 21.71  ? 557 PRO A CB    1 
ATOM   3933 C CG    . PRO A 1 557 ? 147.788 130.728 160.364 1.00 22.89  ? 557 PRO A CG    1 
ATOM   3934 C CD    . PRO A 1 557 ? 148.791 130.106 159.448 1.00 20.87  ? 557 PRO A CD    1 
ATOM   3935 N N     . LEU A 1 558 ? 146.298 132.381 156.185 1.00 27.14  ? 558 LEU A N     1 
ATOM   3936 C CA    . LEU A 1 558 ? 146.379 133.348 155.101 1.00 26.69  ? 558 LEU A CA    1 
ATOM   3937 C C     . LEU A 1 558 ? 145.428 134.504 155.369 1.00 30.67  ? 558 LEU A C     1 
ATOM   3938 O O     . LEU A 1 558 ? 144.215 134.306 155.466 1.00 33.01  ? 558 LEU A O     1 
ATOM   3939 C CB    . LEU A 1 558 ? 146.040 132.692 153.763 1.00 29.43  ? 558 LEU A CB    1 
ATOM   3940 C CG    . LEU A 1 558 ? 145.842 133.644 152.585 1.00 36.00  ? 558 LEU A CG    1 
ATOM   3941 C CD1   . LEU A 1 558 ? 147.161 134.277 152.164 1.00 37.02  ? 558 LEU A CD1   1 
ATOM   3942 C CD2   . LEU A 1 558 ? 145.191 132.924 151.420 1.00 35.13  ? 558 LEU A CD2   1 
ATOM   3943 N N     . LEU A 1 559 ? 145.974 135.708 155.467 1.00 32.99  ? 559 LEU A N     1 
ATOM   3944 C CA    . LEU A 1 559 ? 145.181 136.924 155.525 1.00 31.55  ? 559 LEU A CA    1 
ATOM   3945 C C     . LEU A 1 559 ? 145.242 137.551 154.146 1.00 34.44  ? 559 LEU A C     1 
ATOM   3946 O O     . LEU A 1 559 ? 146.321 137.654 153.563 1.00 38.68  ? 559 LEU A O     1 
ATOM   3947 C CB    . LEU A 1 559 ? 145.700 137.892 156.591 1.00 31.70  ? 559 LEU A CB    1 
ATOM   3948 C CG    . LEU A 1 559 ? 145.929 137.334 157.999 1.00 28.54  ? 559 LEU A CG    1 
ATOM   3949 C CD1   . LEU A 1 559 ? 147.336 136.776 158.158 1.00 34.56  ? 559 LEU A CD1   1 
ATOM   3950 C CD2   . LEU A 1 559 ? 145.669 138.393 159.037 1.00 21.68  ? 559 LEU A CD2   1 
ATOM   3951 N N     . GLU A 1 560 ? 144.084 137.920 153.612 1.00 38.11  ? 560 GLU A N     1 
ATOM   3952 C CA    . GLU A 1 560 ? 143.938 138.318 152.219 1.00 43.52  ? 560 GLU A CA    1 
ATOM   3953 C C     . GLU A 1 560 ? 143.275 139.682 152.180 1.00 43.07  ? 560 GLU A C     1 
ATOM   3954 O O     . GLU A 1 560 ? 142.242 139.889 152.825 1.00 45.06  ? 560 GLU A O     1 
ATOM   3955 C CB    . GLU A 1 560 ? 143.112 137.285 151.445 1.00 49.25  ? 560 GLU A CB    1 
ATOM   3956 C CG    . GLU A 1 560 ? 142.832 137.648 149.999 1.00 56.07  ? 560 GLU A CG    1 
ATOM   3957 C CD    . GLU A 1 560 ? 141.371 137.963 149.743 1.00 58.94  ? 560 GLU A CD    1 
ATOM   3958 O OE1   . GLU A 1 560 ? 140.583 137.958 150.710 1.00 56.75  ? 560 GLU A OE1   1 
ATOM   3959 O OE2   . GLU A 1 560 ? 141.011 138.215 148.574 1.00 59.72  ? 560 GLU A OE2   1 
ATOM   3960 N N     . ALA A 1 561 ? 143.861 140.610 151.431 1.00 44.22  ? 561 ALA A N     1 
ATOM   3961 C CA    . ALA A 1 561 ? 143.370 141.976 151.379 1.00 48.07  ? 561 ALA A CA    1 
ATOM   3962 C C     . ALA A 1 561 ? 143.138 142.370 149.931 1.00 51.86  ? 561 ALA A C     1 
ATOM   3963 O O     . ALA A 1 561 ? 144.038 142.218 149.101 1.00 55.07  ? 561 ALA A O     1 
ATOM   3964 C CB    . ALA A 1 561 ? 144.376 142.921 152.035 1.00 49.02  ? 561 ALA A CB    1 
ATOM   3965 N N     . GLY A 1 562 ? 141.959 142.902 149.633 1.00 51.86  ? 562 GLY A N     1 
ATOM   3966 C CA    . GLY A 1 562 ? 141.646 143.297 148.269 1.00 49.94  ? 562 GLY A CA    1 
ATOM   3967 C C     . GLY A 1 562 ? 140.836 144.572 148.230 1.00 44.87  ? 562 GLY A C     1 
ATOM   3968 O O     . GLY A 1 562 ? 140.079 144.875 149.156 1.00 43.83  ? 562 GLY A O     1 
ATOM   3969 N N     . THR A 1 563 ? 140.999 145.326 147.141 1.00 48.54  ? 563 THR A N     1 
ATOM   3970 C CA    . THR A 1 563 ? 140.345 146.618 146.985 1.00 50.51  ? 563 THR A CA    1 
ATOM   3971 C C     . THR A 1 563 ? 139.864 146.802 145.551 1.00 50.95  ? 563 THR A C     1 
ATOM   3972 O O     . THR A 1 563 ? 140.403 146.206 144.616 1.00 55.94  ? 563 THR A O     1 
ATOM   3973 C CB    . THR A 1 563 ? 141.287 147.781 147.353 1.00 50.76  ? 563 THR A CB    1 
ATOM   3974 O OG1   . THR A 1 563 ? 142.513 147.663 146.621 1.00 54.68  ? 563 THR A OG1   1 
ATOM   3975 C CG2   . THR A 1 563 ? 141.596 147.787 148.842 1.00 48.76  ? 563 THR A CG2   1 
ATOM   3976 N N     . MET A 1 564 ? 138.817 147.612 145.398 1.00 56.87  ? 564 MET A N     1 
ATOM   3977 C CA    . MET A 1 564 ? 138.482 148.248 144.126 1.00 68.11  ? 564 MET A CA    1 
ATOM   3978 C C     . MET A 1 564 ? 137.657 149.489 144.437 1.00 69.30  ? 564 MET A C     1 
ATOM   3979 O O     . MET A 1 564 ? 136.613 149.397 145.090 1.00 70.15  ? 564 MET A O     1 
ATOM   3980 C CB    . MET A 1 564 ? 137.738 147.300 143.168 1.00 73.50  ? 564 MET A CB    1 
ATOM   3981 C CG    . MET A 1 564 ? 136.299 146.951 143.523 1.00 79.81  ? 564 MET A CG    1 
ATOM   3982 S SD    . MET A 1 564 ? 135.109 147.417 142.250 1.00 113.64 ? 564 MET A SD    1 
ATOM   3983 C CE    . MET A 1 564 ? 135.646 146.398 140.879 1.00 92.31  ? 564 MET A CE    1 
ATOM   3984 N N     . GLY A 1 565 ? 138.139 150.647 143.997 1.00 69.44  ? 565 GLY A N     1 
ATOM   3985 C CA    . GLY A 1 565 ? 137.472 151.891 144.349 1.00 63.27  ? 565 GLY A CA    1 
ATOM   3986 C C     . GLY A 1 565 ? 137.393 152.051 145.854 1.00 55.40  ? 565 GLY A C     1 
ATOM   3987 O O     . GLY A 1 565 ? 138.376 151.848 146.574 1.00 59.39  ? 565 GLY A O     1 
ATOM   3988 N N     . THR A 1 566 ? 136.210 152.410 146.345 1.00 52.21  ? 566 THR A N     1 
ATOM   3989 C CA    . THR A 1 566 ? 135.975 152.546 147.776 1.00 54.58  ? 566 THR A CA    1 
ATOM   3990 C C     . THR A 1 566 ? 135.508 151.244 148.418 1.00 56.68  ? 566 THR A C     1 
ATOM   3991 O O     . THR A 1 566 ? 135.107 151.253 149.586 1.00 54.54  ? 566 THR A O     1 
ATOM   3992 C CB    . THR A 1 566 ? 134.959 153.660 148.053 1.00 53.15  ? 566 THR A CB    1 
ATOM   3993 O OG1   . THR A 1 566 ? 133.716 153.358 147.407 1.00 60.37  ? 566 THR A OG1   1 
ATOM   3994 C CG2   . THR A 1 566 ? 135.478 154.999 147.546 1.00 56.22  ? 566 THR A CG2   1 
ATOM   3995 N N     . ARG A 1 567 ? 135.556 150.134 147.683 1.00 54.94  ? 567 ARG A N     1 
ATOM   3996 C CA    . ARG A 1 567 ? 135.214 148.817 148.203 1.00 51.17  ? 567 ARG A CA    1 
ATOM   3997 C C     . ARG A 1 567 ? 136.489 148.096 148.616 1.00 52.15  ? 567 ARG A C     1 
ATOM   3998 O O     . ARG A 1 567 ? 137.487 148.130 147.891 1.00 56.18  ? 567 ARG A O     1 
ATOM   3999 C CB    . ARG A 1 567 ? 134.468 147.980 147.160 1.00 56.01  ? 567 ARG A CB    1 
ATOM   4000 C CG    . ARG A 1 567 ? 133.479 148.741 146.291 1.00 62.29  ? 567 ARG A CG    1 
ATOM   4001 C CD    . ARG A 1 567 ? 132.838 147.809 145.268 1.00 66.03  ? 567 ARG A CD    1 
ATOM   4002 N NE    . ARG A 1 567 ? 132.417 148.511 144.060 1.00 71.15  ? 567 ARG A NE    1 
ATOM   4003 C CZ    . ARG A 1 567 ? 131.168 148.866 143.794 1.00 71.91  ? 567 ARG A CZ    1 
ATOM   4004 N NH1   . ARG A 1 567 ? 130.177 148.586 144.624 1.00 75.47  ? 567 ARG A NH1   1 
ATOM   4005 N NH2   . ARG A 1 567 ? 130.906 149.522 142.666 1.00 67.33  ? 567 ARG A NH2   1 
ATOM   4006 N N     . GLY A 1 568 ? 136.455 147.457 149.774 1.00 47.43  ? 568 GLY A N     1 
ATOM   4007 C CA    . GLY A 1 568 ? 137.577 146.660 150.230 1.00 40.80  ? 568 GLY A CA    1 
ATOM   4008 C C     . GLY A 1 568 ? 137.101 145.463 151.020 1.00 41.43  ? 568 GLY A C     1 
ATOM   4009 O O     . GLY A 1 568 ? 136.039 145.484 151.642 1.00 44.88  ? 568 GLY A O     1 
ATOM   4010 N N     . SER A 1 569 ? 137.897 144.401 150.978 1.00 38.95  ? 569 SER A N     1 
ATOM   4011 C CA    . SER A 1 569 ? 137.646 143.227 151.797 1.00 38.62  ? 569 SER A CA    1 
ATOM   4012 C C     . SER A 1 569 ? 138.933 142.758 152.450 1.00 41.76  ? 569 SER A C     1 
ATOM   4013 O O     . SER A 1 569 ? 140.025 142.859 151.877 1.00 46.17  ? 569 SER A O     1 
ATOM   4014 C CB    . SER A 1 569 ? 137.051 142.072 150.996 1.00 43.79  ? 569 SER A CB    1 
ATOM   4015 O OG    . SER A 1 569 ? 138.025 141.508 150.136 1.00 51.94  ? 569 SER A OG    1 
ATOM   4016 N N     . ALA A 1 570 ? 138.776 142.235 153.662 1.00 42.23  ? 570 ALA A N     1 
ATOM   4017 C CA    . ALA A 1 570 ? 139.842 141.557 154.385 1.00 41.46  ? 570 ALA A CA    1 
ATOM   4018 C C     . ALA A 1 570 ? 139.307 140.215 154.857 1.00 36.93  ? 570 ALA A C     1 
ATOM   4019 O O     . ALA A 1 570 ? 138.292 140.159 155.560 1.00 35.11  ? 570 ALA A O     1 
ATOM   4020 C CB    . ALA A 1 570 ? 140.335 142.393 155.567 1.00 36.71  ? 570 ALA A CB    1 
ATOM   4021 N N     . SER A 1 571 ? 139.985 139.142 154.474 1.00 35.87  ? 571 SER A N     1 
ATOM   4022 C CA    . SER A 1 571 ? 139.593 137.794 154.846 1.00 36.46  ? 571 SER A CA    1 
ATOM   4023 C C     . SER A 1 571 ? 140.730 137.115 155.595 1.00 39.41  ? 571 SER A C     1 
ATOM   4024 O O     . SER A 1 571 ? 141.902 137.430 155.387 1.00 43.90  ? 571 SER A O     1 
ATOM   4025 C CB    . SER A 1 571 ? 139.209 136.977 153.611 1.00 41.24  ? 571 SER A CB    1 
ATOM   4026 O OG    . SER A 1 571 ? 138.170 137.615 152.886 1.00 51.32  ? 571 SER A OG    1 
ATOM   4027 N N     . VAL A 1 572 ? 140.377 136.190 156.481 1.00 34.07  ? 572 VAL A N     1 
ATOM   4028 C CA    . VAL A 1 572 ? 141.355 135.371 157.187 1.00 31.83  ? 572 VAL A CA    1 
ATOM   4029 C C     . VAL A 1 572 ? 140.952 133.911 157.041 1.00 32.95  ? 572 VAL A C     1 
ATOM   4030 O O     . VAL A 1 572 ? 139.827 133.532 157.384 1.00 33.30  ? 572 VAL A O     1 
ATOM   4031 C CB    . VAL A 1 572 ? 141.481 135.767 158.673 1.00 34.68  ? 572 VAL A CB    1 
ATOM   4032 C CG1   . VAL A 1 572 ? 140.113 135.895 159.325 1.00 34.59  ? 572 VAL A CG1   1 
ATOM   4033 C CG2   . VAL A 1 572 ? 142.353 134.772 159.422 1.00 34.65  ? 572 VAL A CG2   1 
ATOM   4034 N N     . PHE A 1 573 ? 141.866 133.097 156.524 1.00 32.54  ? 573 PHE A N     1 
ATOM   4035 C CA    . PHE A 1 573 ? 141.648 131.671 156.316 1.00 28.39  ? 573 PHE A CA    1 
ATOM   4036 C C     . PHE A 1 573 ? 142.629 130.922 157.205 1.00 24.50  ? 573 PHE A C     1 
ATOM   4037 O O     . PHE A 1 573 ? 143.844 130.976 156.983 1.00 27.43  ? 573 PHE A O     1 
ATOM   4038 C CB    . PHE A 1 573 ? 141.827 131.299 154.846 1.00 30.56  ? 573 PHE A CB    1 
ATOM   4039 C CG    . PHE A 1 573 ? 141.077 132.195 153.903 1.00 31.81  ? 573 PHE A CG    1 
ATOM   4040 C CD1   . PHE A 1 573 ? 139.704 132.096 153.779 1.00 35.37  ? 573 PHE A CD1   1 
ATOM   4041 C CD2   . PHE A 1 573 ? 141.745 133.135 153.142 1.00 32.06  ? 573 PHE A CD2   1 
ATOM   4042 C CE1   . PHE A 1 573 ? 139.013 132.914 152.915 1.00 38.40  ? 573 PHE A CE1   1 
ATOM   4043 C CE2   . PHE A 1 573 ? 141.059 133.957 152.275 1.00 38.89  ? 573 PHE A CE2   1 
ATOM   4044 C CZ    . PHE A 1 573 ? 139.692 133.846 152.161 1.00 42.75  ? 573 PHE A CZ    1 
ATOM   4045 N N     . ILE A 1 574 ? 142.100 130.244 158.211 1.00 23.20  ? 574 ILE A N     1 
ATOM   4046 C CA    . ILE A 1 574 ? 142.887 129.519 159.205 1.00 21.10  ? 574 ILE A CA    1 
ATOM   4047 C C     . ILE A 1 574 ? 142.693 128.031 158.955 1.00 21.85  ? 574 ILE A C     1 
ATOM   4048 O O     . ILE A 1 574 ? 141.549 127.583 158.826 1.00 25.46  ? 574 ILE A O     1 
ATOM   4049 C CB    . ILE A 1 574 ? 142.471 129.883 160.644 1.00 22.87  ? 574 ILE A CB    1 
ATOM   4050 C CG1   . ILE A 1 574 ? 142.256 131.388 160.780 1.00 24.23  ? 574 ILE A CG1   1 
ATOM   4051 C CG2   . ILE A 1 574 ? 143.514 129.402 161.639 1.00 25.25  ? 574 ILE A CG2   1 
ATOM   4052 C CD1   . ILE A 1 574 ? 140.812 131.814 160.627 1.00 27.00  ? 574 ILE A CD1   1 
ATOM   4053 N N     . PRO A 1 575 ? 143.762 127.245 158.864 1.00 17.91  ? 575 PRO A N     1 
ATOM   4054 C CA    . PRO A 1 575 ? 143.603 125.819 158.565 1.00 21.99  ? 575 PRO A CA    1 
ATOM   4055 C C     . PRO A 1 575 ? 142.740 125.112 159.599 1.00 24.76  ? 575 PRO A C     1 
ATOM   4056 O O     . PRO A 1 575 ? 142.844 125.364 160.802 1.00 28.22  ? 575 PRO A O     1 
ATOM   4057 C CB    . PRO A 1 575 ? 145.041 125.297 158.579 1.00 21.67  ? 575 PRO A CB    1 
ATOM   4058 C CG    . PRO A 1 575 ? 145.858 126.492 158.228 1.00 20.09  ? 575 PRO A CG    1 
ATOM   4059 C CD    . PRO A 1 575 ? 145.175 127.652 158.873 1.00 18.04  ? 575 PRO A CD    1 
ATOM   4060 N N     . HIS A 1 576 ? 141.870 124.232 159.107 1.00 26.95  ? 576 HIS A N     1 
ATOM   4061 C CA    . HIS A 1 576 ? 141.016 123.374 159.926 1.00 24.05  ? 576 HIS A CA    1 
ATOM   4062 C C     . HIS A 1 576 ? 140.035 124.163 160.787 1.00 26.34  ? 576 HIS A C     1 
ATOM   4063 O O     . HIS A 1 576 ? 139.477 123.619 161.744 1.00 29.49  ? 576 HIS A O     1 
ATOM   4064 C CB    . HIS A 1 576 ? 141.858 122.440 160.800 1.00 24.03  ? 576 HIS A CB    1 
ATOM   4065 C CG    . HIS A 1 576 ? 142.648 121.436 160.022 1.00 34.81  ? 576 HIS A CG    1 
ATOM   4066 N ND1   . HIS A 1 576 ? 143.979 121.177 160.272 1.00 39.23  ? 576 HIS A ND1   1 
ATOM   4067 C CD2   . HIS A 1 576 ? 142.292 120.620 159.001 1.00 37.43  ? 576 HIS A CD2   1 
ATOM   4068 C CE1   . HIS A 1 576 ? 144.409 120.249 159.436 1.00 42.27  ? 576 HIS A CE1   1 
ATOM   4069 N NE2   . HIS A 1 576 ? 143.406 119.894 158.655 1.00 39.15  ? 576 HIS A NE2   1 
ATOM   4070 N N     . VAL A 1 577 ? 139.812 125.439 160.475 1.00 29.54  ? 577 VAL A N     1 
ATOM   4071 C CA    . VAL A 1 577 ? 138.889 126.272 161.242 1.00 27.14  ? 577 VAL A CA    1 
ATOM   4072 C C     . VAL A 1 577 ? 137.864 126.918 160.317 1.00 27.51  ? 577 VAL A C     1 
ATOM   4073 O O     . VAL A 1 577 ? 136.657 126.856 160.573 1.00 30.88  ? 577 VAL A O     1 
ATOM   4074 C CB    . VAL A 1 577 ? 139.642 127.338 162.055 1.00 26.93  ? 577 VAL A CB    1 
ATOM   4075 C CG1   . VAL A 1 577 ? 138.661 128.206 162.814 1.00 29.79  ? 577 VAL A CG1   1 
ATOM   4076 C CG2   . VAL A 1 577 ? 140.618 126.682 163.015 1.00 27.18  ? 577 VAL A CG2   1 
ATOM   4077 N N     . THR A 1 578 ? 138.334 127.550 159.248 1.00 25.09  ? 578 THR A N     1 
ATOM   4078 C CA    . THR A 1 578 ? 137.484 128.272 158.310 1.00 29.48  ? 578 THR A CA    1 
ATOM   4079 C C     . THR A 1 578 ? 137.605 127.652 156.917 1.00 34.89  ? 578 THR A C     1 
ATOM   4080 O O     . THR A 1 578 ? 138.235 126.611 156.732 1.00 37.82  ? 578 THR A O     1 
ATOM   4081 C CB    . THR A 1 578 ? 137.847 129.757 158.287 1.00 29.43  ? 578 THR A CB    1 
ATOM   4082 O OG1   . THR A 1 578 ? 139.224 129.905 157.924 1.00 27.15  ? 578 THR A OG1   1 
ATOM   4083 C CG2   . THR A 1 578 ? 137.611 130.384 159.652 1.00 30.49  ? 578 THR A CG2   1 
ATOM   4084 N N     . GLU A 1 579 ? 136.988 128.300 155.936 1.00 33.09  ? 579 GLU A N     1 
ATOM   4085 C CA    . GLU A 1 579 ? 136.994 127.816 154.566 1.00 34.58  ? 579 GLU A CA    1 
ATOM   4086 C C     . GLU A 1 579 ? 138.236 128.302 153.822 1.00 34.96  ? 579 GLU A C     1 
ATOM   4087 O O     . GLU A 1 579 ? 138.983 129.161 154.293 1.00 37.01  ? 579 GLU A O     1 
ATOM   4088 C CB    . GLU A 1 579 ? 135.726 128.257 153.834 1.00 40.50  ? 579 GLU A CB    1 
ATOM   4089 C CG    . GLU A 1 579 ? 135.711 129.718 153.398 1.00 45.48  ? 579 GLU A CG    1 
ATOM   4090 C CD    . GLU A 1 579 ? 135.069 130.643 154.418 1.00 51.80  ? 579 GLU A CD    1 
ATOM   4091 O OE1   . GLU A 1 579 ? 135.500 130.646 155.589 1.00 50.02  ? 579 GLU A OE1   1 
ATOM   4092 O OE2   . GLU A 1 579 ? 134.124 131.369 154.043 1.00 53.29  ? 579 GLU A OE2   1 
ATOM   4093 N N     . ASN A 1 580 ? 138.460 127.719 152.648 1.00 33.10  ? 580 ASN A N     1 
ATOM   4094 C CA    . ASN A 1 580 ? 139.529 128.145 151.760 1.00 36.17  ? 580 ASN A CA    1 
ATOM   4095 C C     . ASN A 1 580 ? 139.090 129.351 150.935 1.00 42.06  ? 580 ASN A C     1 
ATOM   4096 O O     . ASN A 1 580 ? 137.900 129.657 150.816 1.00 48.90  ? 580 ASN A O     1 
ATOM   4097 C CB    . ASN A 1 580 ? 139.944 127.007 150.826 1.00 41.13  ? 580 ASN A CB    1 
ATOM   4098 C CG    . ASN A 1 580 ? 140.714 125.919 151.538 1.00 37.29  ? 580 ASN A CG    1 
ATOM   4099 O OD1   . ASN A 1 580 ? 140.752 125.872 152.763 1.00 35.20  ? 580 ASN A OD1   1 
ATOM   4100 N ND2   . ASN A 1 580 ? 141.337 125.034 150.767 1.00 37.89  ? 580 ASN A ND2   1 
ATOM   4101 N N     . TYR A 1 581 ? 140.071 130.043 150.362 1.00 39.92  ? 581 TYR A N     1 
ATOM   4102 C CA    . TYR A 1 581 ? 139.772 131.145 149.459 1.00 43.68  ? 581 TYR A CA    1 
ATOM   4103 C C     . TYR A 1 581 ? 139.198 130.613 148.152 1.00 51.83  ? 581 TYR A C     1 
ATOM   4104 O O     . TYR A 1 581 ? 139.752 129.689 147.549 1.00 57.78  ? 581 TYR A O     1 
ATOM   4105 C CB    . TYR A 1 581 ? 141.029 131.972 149.194 1.00 41.89  ? 581 TYR A CB    1 
ATOM   4106 C CG    . TYR A 1 581 ? 140.915 132.913 148.017 1.00 45.10  ? 581 TYR A CG    1 
ATOM   4107 C CD1   . TYR A 1 581 ? 140.123 134.052 148.084 1.00 46.47  ? 581 TYR A CD1   1 
ATOM   4108 C CD2   . TYR A 1 581 ? 141.608 132.667 146.842 1.00 47.44  ? 581 TYR A CD2   1 
ATOM   4109 C CE1   . TYR A 1 581 ? 140.017 134.911 147.010 1.00 53.29  ? 581 TYR A CE1   1 
ATOM   4110 C CE2   . TYR A 1 581 ? 141.513 133.520 145.767 1.00 51.01  ? 581 TYR A CE2   1 
ATOM   4111 C CZ    . TYR A 1 581 ? 140.715 134.641 145.853 1.00 56.42  ? 581 TYR A CZ    1 
ATOM   4112 O OH    . TYR A 1 581 ? 140.619 135.493 144.777 1.00 56.67  ? 581 TYR A OH    1 
ATOM   4113 N N     . LYS A 1 582 ? 138.088 131.202 147.713 1.00 50.24  ? 582 LYS A N     1 
ATOM   4114 C CA    . LYS A 1 582 ? 137.417 130.817 146.477 1.00 49.93  ? 582 LYS A CA    1 
ATOM   4115 C C     . LYS A 1 582 ? 137.513 131.969 145.485 1.00 53.45  ? 582 LYS A C     1 
ATOM   4116 O O     . LYS A 1 582 ? 136.928 133.034 145.706 1.00 56.70  ? 582 LYS A O     1 
ATOM   4117 C CB    . LYS A 1 582 ? 135.958 130.448 146.742 1.00 49.69  ? 582 LYS A CB    1 
ATOM   4118 C CG    . LYS A 1 582 ? 135.775 129.114 147.445 1.00 55.87  ? 582 LYS A CG    1 
ATOM   4119 C CD    . LYS A 1 582 ? 136.295 127.969 146.591 1.00 64.60  ? 582 LYS A CD    1 
ATOM   4120 C CE    . LYS A 1 582 ? 135.823 126.625 147.124 1.00 68.09  ? 582 LYS A CE    1 
ATOM   4121 N NZ    . LYS A 1 582 ? 136.213 126.418 148.547 1.00 68.49  ? 582 LYS A NZ    1 
ATOM   4122 N N     . ALA A 1 583 ? 138.273 131.746 144.368 1.00 52.38  ? 583 ALA A N     1 
ATOM   4123 C CA    . ALA A 1 583 ? 138.525 132.759 143.356 1.00 53.93  ? 583 ALA A CA    1 
ATOM   4124 C C     . ALA A 1 583 ? 137.519 132.661 142.213 1.00 63.05  ? 583 ALA A C     1 
ATOM   4125 O O     . ALA A 1 583 ? 137.041 131.570 141.886 1.00 67.06  ? 583 ALA A O     1 
ATOM   4126 C CB    . ALA A 1 583 ? 139.939 132.616 142.802 1.00 51.69  ? 583 ALA A CB    1 
ATOM   4127 N N     . PRO A 1 584 ? 137.178 133.793 141.602 1.00 67.60  ? 584 PRO A N     1 
ATOM   4128 C CA    . PRO A 1 584 ? 136.391 133.762 140.365 1.00 72.03  ? 584 PRO A CA    1 
ATOM   4129 C C     . PRO A 1 584 ? 137.250 133.364 139.176 1.00 73.99  ? 584 PRO A C     1 
ATOM   4130 O O     . PRO A 1 584 ? 138.482 133.384 139.224 1.00 72.65  ? 584 PRO A O     1 
ATOM   4131 C CB    . PRO A 1 584 ? 135.887 135.202 140.230 1.00 73.34  ? 584 PRO A CB    1 
ATOM   4132 C CG    . PRO A 1 584 ? 136.921 136.014 140.929 1.00 69.13  ? 584 PRO A CG    1 
ATOM   4133 C CD    . PRO A 1 584 ? 137.398 135.169 142.081 1.00 68.20  ? 584 PRO A CD    1 
ATOM   4134 N N     . SER A 1 585 ? 136.570 132.983 138.099 1.00 80.88  ? 585 SER A N     1 
ATOM   4135 C CA    . SER A 1 585 ? 137.236 132.583 136.864 1.00 90.19  ? 585 SER A CA    1 
ATOM   4136 C C     . SER A 1 585 ? 138.055 133.726 136.279 1.00 87.05  ? 585 SER A C     1 
ATOM   4137 O O     . SER A 1 585 ? 138.429 133.693 135.108 1.00 84.18  ? 585 SER A O     1 
ATOM   4138 C CB    . SER A 1 585 ? 136.209 132.099 135.839 1.00 89.55  ? 585 SER A CB    1 
ATOM   4139 O OG    . SER A 1 585 ? 135.441 131.030 136.359 1.00 83.15  ? 585 SER A OG    1 
ATOM   4140 N N     . ASP A 1 594 ? 137.200 138.717 124.726 1.00 136.33 ? 594 ASP A N     1 
ATOM   4141 C CA    . ASP A 1 594 ? 136.254 137.961 123.911 1.00 138.57 ? 594 ASP A CA    1 
ATOM   4142 C C     . ASP A 1 594 ? 136.870 137.530 122.578 1.00 141.46 ? 594 ASP A C     1 
ATOM   4143 O O     . ASP A 1 594 ? 137.760 138.200 122.053 1.00 142.62 ? 594 ASP A O     1 
ATOM   4144 C CB    . ASP A 1 594 ? 134.982 138.782 123.686 1.00 140.08 ? 594 ASP A CB    1 
ATOM   4145 C CG    . ASP A 1 594 ? 134.071 138.767 124.897 1.00 137.82 ? 594 ASP A CG    1 
ATOM   4146 O OD1   . ASP A 1 594 ? 134.490 138.222 125.939 1.00 137.01 ? 594 ASP A OD1   1 
ATOM   4147 O OD2   . ASP A 1 594 ? 132.937 139.282 124.809 1.00 138.72 ? 594 ASP A OD2   1 
ATOM   4148 N N     . PRO A 1 595 ? 136.408 136.396 122.048 1.00 141.60 ? 595 PRO A N     1 
ATOM   4149 C CA    . PRO A 1 595 ? 137.028 135.833 120.842 1.00 140.29 ? 595 PRO A CA    1 
ATOM   4150 C C     . PRO A 1 595 ? 136.934 136.766 119.644 1.00 140.49 ? 595 PRO A C     1 
ATOM   4151 O O     . PRO A 1 595 ? 135.989 137.546 119.503 1.00 142.66 ? 595 PRO A O     1 
ATOM   4152 C CB    . PRO A 1 595 ? 136.232 134.544 120.607 1.00 135.67 ? 595 PRO A CB    1 
ATOM   4153 C CG    . PRO A 1 595 ? 135.712 134.178 121.951 1.00 132.29 ? 595 PRO A CG    1 
ATOM   4154 C CD    . PRO A 1 595 ? 135.404 135.485 122.624 1.00 136.54 ? 595 PRO A CD    1 
ATOM   4155 N N     . VAL A 1 596 ? 137.941 136.668 118.770 1.00 135.06 ? 596 VAL A N     1 
ATOM   4156 C CA    . VAL A 1 596 ? 137.972 137.451 117.539 1.00 130.57 ? 596 VAL A CA    1 
ATOM   4157 C C     . VAL A 1 596 ? 136.803 137.116 116.624 1.00 133.78 ? 596 VAL A C     1 
ATOM   4158 O O     . VAL A 1 596 ? 136.570 137.825 115.639 1.00 136.93 ? 596 VAL A O     1 
ATOM   4159 C CB    . VAL A 1 596 ? 139.312 137.250 116.797 1.00 124.05 ? 596 VAL A CB    1 
ATOM   4160 C CG1   . VAL A 1 596 ? 140.486 137.641 117.688 1.00 128.09 ? 596 VAL A CG1   1 
ATOM   4161 C CG2   . VAL A 1 596 ? 139.448 135.816 116.306 1.00 124.85 ? 596 VAL A CG2   1 
ATOM   4162 N N     . CYS A 1 597 ? 136.073 136.034 116.913 1.00 132.26 ? 597 CYS A N     1 
ATOM   4163 C CA    . CYS A 1 597 ? 134.943 135.633 116.078 1.00 131.88 ? 597 CYS A CA    1 
ATOM   4164 C C     . CYS A 1 597 ? 133.955 136.773 115.872 1.00 134.44 ? 597 CYS A C     1 
ATOM   4165 O O     . CYS A 1 597 ? 133.494 137.011 114.750 1.00 128.63 ? 597 CYS A O     1 
ATOM   4166 C CB    . CYS A 1 597 ? 134.233 134.439 116.712 1.00 132.50 ? 597 CYS A CB    1 
ATOM   4167 S SG    . CYS A 1 597 ? 135.351 133.205 117.379 1.00 123.20 ? 597 CYS A SG    1 
ATOM   4168 N N     . THR A 1 598 ? 133.612 137.485 116.944 1.00 138.63 ? 598 THR A N     1 
ATOM   4169 C CA    . THR A 1 598 ? 132.664 138.589 116.852 1.00 136.00 ? 598 THR A CA    1 
ATOM   4170 C C     . THR A 1 598 ? 133.366 139.940 116.764 1.00 135.08 ? 598 THR A C     1 
ATOM   4171 O O     . THR A 1 598 ? 132.889 140.843 116.071 1.00 136.11 ? 598 THR A O     1 
ATOM   4172 C CB    . THR A 1 598 ? 131.701 138.564 118.044 1.00 137.68 ? 598 THR A CB    1 
ATOM   4173 O OG1   . THR A 1 598 ? 132.444 138.612 119.269 1.00 138.99 ? 598 THR A OG1   1 
ATOM   4174 C CG2   . THR A 1 598 ? 130.850 137.300 118.015 1.00 129.85 ? 598 THR A CG2   1 
ATOM   4175 N N     . VAL A 1 599 ? 134.491 140.095 117.467 1.00 135.26 ? 599 VAL A N     1 
ATOM   4176 C CA    . VAL A 1 599 ? 135.178 141.383 117.525 1.00 138.34 ? 599 VAL A CA    1 
ATOM   4177 C C     . VAL A 1 599 ? 135.658 141.825 116.146 1.00 135.80 ? 599 VAL A C     1 
ATOM   4178 O O     . VAL A 1 599 ? 135.628 143.020 115.824 1.00 135.99 ? 599 VAL A O     1 
ATOM   4179 C CB    . VAL A 1 599 ? 136.342 141.303 118.533 1.00 138.68 ? 599 VAL A CB    1 
ATOM   4180 C CG1   . VAL A 1 599 ? 137.057 142.640 118.642 1.00 138.36 ? 599 VAL A CG1   1 
ATOM   4181 C CG2   . VAL A 1 599 ? 135.831 140.848 119.897 1.00 139.59 ? 599 VAL A CG2   1 
ATOM   4182 N N     . ARG A 1 600 ? 136.090 140.882 115.307 1.00 129.77 ? 600 ARG A N     1 
ATOM   4183 C CA    . ARG A 1 600 ? 136.677 141.244 114.020 1.00 121.90 ? 600 ARG A CA    1 
ATOM   4184 C C     . ARG A 1 600 ? 135.652 141.843 113.055 1.00 123.08 ? 600 ARG A C     1 
ATOM   4185 O O     . ARG A 1 600 ? 136.027 142.623 112.172 1.00 122.62 ? 600 ARG A O     1 
ATOM   4186 C CB    . ARG A 1 600 ? 137.351 140.018 113.399 1.00 119.49 ? 600 ARG A CB    1 
ATOM   4187 C CG    . ARG A 1 600 ? 138.126 140.295 112.120 1.00 120.75 ? 600 ARG A CG    1 
ATOM   4188 C CD    . ARG A 1 600 ? 138.800 139.037 111.588 1.00 120.28 ? 600 ARG A CD    1 
ATOM   4189 N NE    . ARG A 1 600 ? 139.863 138.566 112.469 1.00 120.20 ? 600 ARG A NE    1 
ATOM   4190 C CZ    . ARG A 1 600 ? 140.542 137.441 112.293 1.00 119.94 ? 600 ARG A CZ    1 
ATOM   4191 N NH1   . ARG A 1 600 ? 140.292 136.632 111.276 1.00 123.85 ? 600 ARG A NH1   1 
ATOM   4192 N NH2   . ARG A 1 600 ? 141.494 137.116 113.163 1.00 116.93 ? 600 ARG A NH2   1 
ATOM   4193 N N     . TYR A 1 601 ? 134.366 141.514 113.202 1.00 123.32 ? 601 TYR A N     1 
ATOM   4194 C CA    . TYR A 1 601 ? 133.378 141.962 112.218 1.00 118.45 ? 601 TYR A CA    1 
ATOM   4195 C C     . TYR A 1 601 ? 132.113 142.573 112.799 1.00 121.26 ? 601 TYR A C     1 
ATOM   4196 O O     . TYR A 1 601 ? 131.354 143.185 112.039 1.00 124.20 ? 601 TYR A O     1 
ATOM   4197 C CB    . TYR A 1 601 ? 132.976 140.804 111.299 1.00 113.39 ? 601 TYR A CB    1 
ATOM   4198 C CG    . TYR A 1 601 ? 134.142 140.170 110.584 1.00 110.96 ? 601 TYR A CG    1 
ATOM   4199 C CD1   . TYR A 1 601 ? 134.855 140.873 109.626 1.00 107.48 ? 601 TYR A CD1   1 
ATOM   4200 C CD2   . TYR A 1 601 ? 134.529 138.869 110.865 1.00 111.65 ? 601 TYR A CD2   1 
ATOM   4201 C CE1   . TYR A 1 601 ? 135.923 140.301 108.970 1.00 103.86 ? 601 TYR A CE1   1 
ATOM   4202 C CE2   . TYR A 1 601 ? 135.595 138.287 110.213 1.00 107.31 ? 601 TYR A CE2   1 
ATOM   4203 C CZ    . TYR A 1 601 ? 136.288 139.009 109.265 1.00 102.54 ? 601 TYR A CZ    1 
ATOM   4204 O OH    . TYR A 1 601 ? 137.352 138.434 108.612 1.00 97.77  ? 601 TYR A OH    1 
ATOM   4205 N N     . ILE A 1 602 ? 131.843 142.439 114.092 1.00 125.33 ? 602 ILE A N     1 
ATOM   4206 C CA    . ILE A 1 602 ? 130.633 142.993 114.693 1.00 132.20 ? 602 ILE A CA    1 
ATOM   4207 C C     . ILE A 1 602 ? 130.875 143.211 116.186 1.00 137.33 ? 602 ILE A C     1 
ATOM   4208 O O     . ILE A 1 602 ? 130.542 142.349 117.013 1.00 139.98 ? 602 ILE A O     1 
ATOM   4209 C CB    . ILE A 1 602 ? 129.415 142.092 114.410 1.00 134.82 ? 602 ILE A CB    1 
ATOM   4210 C CG1   . ILE A 1 602 ? 128.170 142.577 115.163 1.00 139.06 ? 602 ILE A CG1   1 
ATOM   4211 C CG2   . ILE A 1 602 ? 129.738 140.615 114.671 1.00 132.27 ? 602 ILE A CG2   1 
ATOM   4212 C CD1   . ILE A 1 602 ? 127.693 143.947 114.736 1.00 137.95 ? 602 ILE A CD1   1 
ATOM   4213 N N     . PRO A 1 603 ? 131.483 144.329 116.574 1.00 140.40 ? 603 PRO A N     1 
ATOM   4214 C CA    . PRO A 1 603 ? 131.651 144.623 118.004 1.00 146.36 ? 603 PRO A CA    1 
ATOM   4215 C C     . PRO A 1 603 ? 130.357 145.094 118.652 1.00 148.57 ? 603 PRO A C     1 
ATOM   4216 O O     . PRO A 1 603 ? 129.821 146.148 118.295 1.00 146.19 ? 603 PRO A O     1 
ATOM   4217 C CB    . PRO A 1 603 ? 132.721 145.720 118.008 1.00 144.88 ? 603 PRO A CB    1 
ATOM   4218 C CG    . PRO A 1 603 ? 132.566 146.393 116.688 1.00 140.46 ? 603 PRO A CG    1 
ATOM   4219 C CD    . PRO A 1 603 ? 132.144 145.327 115.716 1.00 136.82 ? 603 PRO A CD    1 
ATOM   4220 N N     . ALA A 1 604 ? 129.839 144.318 119.604 1.00 148.64 ? 604 ALA A N     1 
ATOM   4221 C CA    . ALA A 1 604 ? 128.571 144.642 120.244 1.00 147.11 ? 604 ALA A CA    1 
ATOM   4222 C C     . ALA A 1 604 ? 128.716 145.521 121.480 1.00 149.50 ? 604 ALA A C     1 
ATOM   4223 O O     . ALA A 1 604 ? 127.718 146.096 121.930 1.00 148.57 ? 604 ALA A O     1 
ATOM   4224 C CB    . ALA A 1 604 ? 127.831 143.357 120.628 1.00 140.02 ? 604 ALA A CB    1 
ATOM   4225 N N     . THR A 1 605 ? 129.918 145.643 122.040 1.00 151.31 ? 605 THR A N     1 
ATOM   4226 C CA    . THR A 1 605 ? 130.114 146.357 123.294 1.00 151.62 ? 605 THR A CA    1 
ATOM   4227 C C     . THR A 1 605 ? 131.333 147.264 123.187 1.00 150.68 ? 605 THR A C     1 
ATOM   4228 O O     . THR A 1 605 ? 132.104 147.202 122.225 1.00 147.44 ? 605 THR A O     1 
ATOM   4229 C CB    . THR A 1 605 ? 130.286 145.393 124.479 1.00 152.84 ? 605 THR A CB    1 
ATOM   4230 O OG1   . THR A 1 605 ? 131.362 144.486 124.209 1.00 155.03 ? 605 THR A OG1   1 
ATOM   4231 C CG2   . THR A 1 605 ? 129.008 144.603 124.733 1.00 147.55 ? 605 THR A CG2   1 
ATOM   4232 N N     . THR A 1 606 ? 131.491 148.123 124.197 1.00 154.85 ? 606 THR A N     1 
ATOM   4233 C CA    . THR A 1 606 ? 132.665 148.989 124.263 1.00 157.91 ? 606 THR A CA    1 
ATOM   4234 C C     . THR A 1 606 ? 133.943 148.174 124.417 1.00 156.36 ? 606 THR A C     1 
ATOM   4235 O O     . THR A 1 606 ? 134.974 148.498 123.813 1.00 153.14 ? 606 THR A O     1 
ATOM   4236 C CB    . THR A 1 606 ? 132.518 149.982 125.416 1.00 160.18 ? 606 THR A CB    1 
ATOM   4237 O OG1   . THR A 1 606 ? 131.298 150.717 125.260 1.00 161.03 ? 606 THR A OG1   1 
ATOM   4238 C CG2   . THR A 1 606 ? 133.689 150.956 125.437 1.00 156.67 ? 606 THR A CG2   1 
ATOM   4239 N N     . GLU A 1 607 ? 133.897 147.114 125.229 1.00 159.03 ? 607 GLU A N     1 
ATOM   4240 C CA    . GLU A 1 607 ? 135.073 146.270 125.409 1.00 157.65 ? 607 GLU A CA    1 
ATOM   4241 C C     . GLU A 1 607 ? 135.514 145.656 124.087 1.00 155.96 ? 607 GLU A C     1 
ATOM   4242 O O     . GLU A 1 607 ? 136.715 145.524 123.828 1.00 154.76 ? 607 GLU A O     1 
ATOM   4243 C CB    . GLU A 1 607 ? 134.792 145.175 126.440 1.00 156.37 ? 607 GLU A CB    1 
ATOM   4244 C CG    . GLU A 1 607 ? 134.661 145.671 127.873 1.00 155.43 ? 607 GLU A CG    1 
ATOM   4245 C CD    . GLU A 1 607 ? 133.244 146.071 128.234 1.00 157.10 ? 607 GLU A CD    1 
ATOM   4246 O OE1   . GLU A 1 607 ? 132.347 145.940 127.375 1.00 157.74 ? 607 GLU A OE1   1 
ATOM   4247 O OE2   . GLU A 1 607 ? 133.028 146.511 129.383 1.00 157.05 ? 607 GLU A OE2   1 
ATOM   4248 N N     . HIS A 1 608 ? 134.556 145.285 123.233 1.00 154.93 ? 608 HIS A N     1 
ATOM   4249 C CA    . HIS A 1 608 ? 134.896 144.721 121.930 1.00 150.40 ? 608 HIS A CA    1 
ATOM   4250 C C     . HIS A 1 608 ? 135.685 145.717 121.089 1.00 145.15 ? 608 HIS A C     1 
ATOM   4251 O O     . HIS A 1 608 ? 136.716 145.370 120.499 1.00 143.58 ? 608 HIS A O     1 
ATOM   4252 C CB    . HIS A 1 608 ? 133.627 144.289 121.193 1.00 150.67 ? 608 HIS A CB    1 
ATOM   4253 C CG    . HIS A 1 608 ? 132.938 143.113 121.811 1.00 153.69 ? 608 HIS A CG    1 
ATOM   4254 N ND1   . HIS A 1 608 ? 131.736 142.626 121.347 1.00 151.53 ? 608 HIS A ND1   1 
ATOM   4255 C CD2   . HIS A 1 608 ? 133.288 142.321 122.851 1.00 154.30 ? 608 HIS A CD2   1 
ATOM   4256 C CE1   . HIS A 1 608 ? 131.372 141.586 122.078 1.00 151.03 ? 608 HIS A CE1   1 
ATOM   4257 N NE2   . HIS A 1 608 ? 132.297 141.381 122.998 1.00 151.99 ? 608 HIS A NE2   1 
ATOM   4258 N N     . THR A 1 609 ? 135.221 146.966 121.028 1.00 144.54 ? 609 THR A N     1 
ATOM   4259 C CA    . THR A 1 609 ? 135.912 147.963 120.215 1.00 145.95 ? 609 THR A CA    1 
ATOM   4260 C C     . THR A 1 609 ? 137.277 148.300 120.799 1.00 143.12 ? 609 THR A C     1 
ATOM   4261 O O     . THR A 1 609 ? 138.248 148.486 120.055 1.00 140.31 ? 609 THR A O     1 
ATOM   4262 C CB    . THR A 1 609 ? 135.059 149.224 120.077 1.00 148.33 ? 609 THR A CB    1 
ATOM   4263 O OG1   . THR A 1 609 ? 134.822 149.792 121.370 1.00 149.02 ? 609 THR A OG1   1 
ATOM   4264 C CG2   . THR A 1 609 ? 133.728 148.893 119.421 1.00 146.73 ? 609 THR A CG2   1 
ATOM   4265 N N     . VAL A 1 610 ? 137.375 148.380 122.128 1.00 145.67 ? 610 VAL A N     1 
ATOM   4266 C CA    . VAL A 1 610 ? 138.668 148.657 122.746 1.00 146.16 ? 610 VAL A CA    1 
ATOM   4267 C C     . VAL A 1 610 ? 139.651 147.530 122.455 1.00 143.51 ? 610 VAL A C     1 
ATOM   4268 O O     . VAL A 1 610 ? 140.820 147.776 122.141 1.00 140.34 ? 610 VAL A O     1 
ATOM   4269 C CB    . VAL A 1 610 ? 138.509 148.898 124.258 1.00 148.98 ? 610 VAL A CB    1 
ATOM   4270 C CG1   . VAL A 1 610 ? 139.871 149.105 124.899 1.00 147.87 ? 610 VAL A CG1   1 
ATOM   4271 C CG2   . VAL A 1 610 ? 137.620 150.105 124.510 1.00 151.52 ? 610 VAL A CG2   1 
ATOM   4272 N N     . GLN A 1 611 ? 139.197 146.278 122.555 1.00 147.32 ? 611 GLN A N     1 
ATOM   4273 C CA    . GLN A 1 611 ? 140.071 145.147 122.256 1.00 146.72 ? 611 GLN A CA    1 
ATOM   4274 C C     . GLN A 1 611 ? 140.478 145.132 120.788 1.00 143.51 ? 611 GLN A C     1 
ATOM   4275 O O     . GLN A 1 611 ? 141.624 144.805 120.461 1.00 141.94 ? 611 GLN A O     1 
ATOM   4276 C CB    . GLN A 1 611 ? 139.385 143.836 122.639 1.00 149.44 ? 611 GLN A CB    1 
ATOM   4277 C CG    . GLN A 1 611 ? 139.232 143.632 124.138 1.00 151.98 ? 611 GLN A CG    1 
ATOM   4278 C CD    . GLN A 1 611 ? 138.449 142.379 124.479 1.00 153.16 ? 611 GLN A CD    1 
ATOM   4279 O OE1   . GLN A 1 611 ? 138.072 141.610 123.595 1.00 151.37 ? 611 GLN A OE1   1 
ATOM   4280 N NE2   . GLN A 1 611 ? 138.200 142.170 125.766 1.00 154.93 ? 611 GLN A NE2   1 
ATOM   4281 N N     . TRP A 1 612 ? 139.552 145.474 119.888 1.00 144.51 ? 612 TRP A N     1 
ATOM   4282 C CA    . TRP A 1 612 ? 139.892 145.548 118.471 1.00 138.94 ? 612 TRP A CA    1 
ATOM   4283 C C     . TRP A 1 612 ? 140.955 146.608 118.216 1.00 131.59 ? 612 TRP A C     1 
ATOM   4284 O O     . TRP A 1 612 ? 141.922 146.366 117.485 1.00 127.73 ? 612 TRP A O     1 
ATOM   4285 C CB    . TRP A 1 612 ? 138.636 145.832 117.647 1.00 137.30 ? 612 TRP A CB    1 
ATOM   4286 C CG    . TRP A 1 612 ? 138.893 146.011 116.183 1.00 133.22 ? 612 TRP A CG    1 
ATOM   4287 C CD1   . TRP A 1 612 ? 139.065 145.026 115.255 1.00 133.98 ? 612 TRP A CD1   1 
ATOM   4288 C CD2   . TRP A 1 612 ? 138.995 147.251 115.475 1.00 128.27 ? 612 TRP A CD2   1 
ATOM   4289 N NE1   . TRP A 1 612 ? 139.274 145.576 114.014 1.00 133.47 ? 612 TRP A NE1   1 
ATOM   4290 C CE2   . TRP A 1 612 ? 139.235 146.942 114.122 1.00 127.93 ? 612 TRP A CE2   1 
ATOM   4291 C CE3   . TRP A 1 612 ? 138.909 148.594 115.854 1.00 126.46 ? 612 TRP A CE3   1 
ATOM   4292 C CZ2   . TRP A 1 612 ? 139.390 147.924 113.149 1.00 121.66 ? 612 TRP A CZ2   1 
ATOM   4293 C CZ3   . TRP A 1 612 ? 139.064 149.567 114.886 1.00 123.97 ? 612 TRP A CZ3   1 
ATOM   4294 C CH2   . TRP A 1 612 ? 139.302 149.228 113.549 1.00 117.90 ? 612 TRP A CH2   1 
ATOM   4295 N N     . ALA A 1 613 ? 140.800 147.786 118.824 1.00 132.88 ? 613 ALA A N     1 
ATOM   4296 C CA    . ALA A 1 613 ? 141.797 148.838 118.660 1.00 130.42 ? 613 ALA A CA    1 
ATOM   4297 C C     . ALA A 1 613 ? 143.138 148.429 119.256 1.00 126.51 ? 613 ALA A C     1 
ATOM   4298 O O     . ALA A 1 613 ? 144.196 148.725 118.688 1.00 122.92 ? 613 ALA A O     1 
ATOM   4299 C CB    . ALA A 1 613 ? 141.300 150.136 119.297 1.00 136.55 ? 613 ALA A CB    1 
ATOM   4300 N N     . LYS A 1 614 ? 143.115 147.757 120.410 1.00 130.13 ? 614 LYS A N     1 
ATOM   4301 C CA    . LYS A 1 614 ? 144.355 147.317 121.037 1.00 131.38 ? 614 LYS A CA    1 
ATOM   4302 C C     . LYS A 1 614 ? 145.074 146.289 120.176 1.00 133.25 ? 614 LYS A C     1 
ATOM   4303 O O     . LYS A 1 614 ? 146.298 146.348 120.025 1.00 134.97 ? 614 LYS A O     1 
ATOM   4304 C CB    . LYS A 1 614 ? 144.069 146.751 122.428 1.00 134.48 ? 614 LYS A CB    1 
ATOM   4305 C CG    . LYS A 1 614 ? 145.306 146.268 123.172 1.00 135.97 ? 614 LYS A CG    1 
ATOM   4306 C CD    . LYS A 1 614 ? 146.367 147.355 123.248 1.00 140.47 ? 614 LYS A CD    1 
ATOM   4307 C CE    . LYS A 1 614 ? 147.512 146.949 124.161 1.00 142.96 ? 614 LYS A CE    1 
ATOM   4308 N NZ    . LYS A 1 614 ? 148.166 145.691 123.710 1.00 137.39 ? 614 LYS A NZ    1 
ATOM   4309 N N     . GLY A 1 615 ? 144.332 145.344 119.597 1.00 136.23 ? 615 GLY A N     1 
ATOM   4310 C CA    . GLY A 1 615 ? 144.947 144.383 118.696 1.00 136.37 ? 615 GLY A CA    1 
ATOM   4311 C C     . GLY A 1 615 ? 145.471 145.031 117.428 1.00 133.56 ? 615 GLY A C     1 
ATOM   4312 O O     . GLY A 1 615 ? 146.517 144.635 116.904 1.00 134.10 ? 615 GLY A O     1 
ATOM   4313 N N     . GLU A 1 616 ? 144.749 146.029 116.914 1.00 130.28 ? 616 GLU A N     1 
ATOM   4314 C CA    . GLU A 1 616 ? 145.231 146.769 115.754 1.00 125.02 ? 616 GLU A CA    1 
ATOM   4315 C C     . GLU A 1 616 ? 146.543 147.475 116.067 1.00 126.05 ? 616 GLU A C     1 
ATOM   4316 O O     . GLU A 1 616 ? 147.487 147.430 115.272 1.00 128.88 ? 616 GLU A O     1 
ATOM   4317 C CB    . GLU A 1 616 ? 144.171 147.773 115.301 1.00 123.50 ? 616 GLU A CB    1 
ATOM   4318 C CG    . GLU A 1 616 ? 144.319 148.239 113.862 1.00 123.49 ? 616 GLU A CG    1 
ATOM   4319 C CD    . GLU A 1 616 ? 143.918 147.174 112.858 1.00 122.19 ? 616 GLU A CD    1 
ATOM   4320 O OE1   . GLU A 1 616 ? 143.235 146.206 113.252 1.00 124.11 ? 616 GLU A OE1   1 
ATOM   4321 O OE2   . GLU A 1 616 ? 144.286 147.306 111.671 1.00 116.32 ? 616 GLU A OE2   1 
ATOM   4322 N N     . PHE A 1 617 ? 146.626 148.118 117.233 1.00 128.75 ? 617 PHE A N     1 
ATOM   4323 C CA    . PHE A 1 617 ? 147.883 148.725 117.658 1.00 132.12 ? 617 PHE A CA    1 
ATOM   4324 C C     . PHE A 1 617 ? 148.973 147.673 117.806 1.00 132.90 ? 617 PHE A C     1 
ATOM   4325 O O     . PHE A 1 617 ? 150.120 147.890 117.397 1.00 135.22 ? 617 PHE A O     1 
ATOM   4326 C CB    . PHE A 1 617 ? 147.676 149.480 118.974 1.00 136.92 ? 617 PHE A CB    1 
ATOM   4327 C CG    . PHE A 1 617 ? 148.936 150.071 119.547 1.00 141.36 ? 617 PHE A CG    1 
ATOM   4328 C CD1   . PHE A 1 617 ? 149.342 151.346 119.192 1.00 144.00 ? 617 PHE A CD1   1 
ATOM   4329 C CD2   . PHE A 1 617 ? 149.702 149.361 120.457 1.00 143.29 ? 617 PHE A CD2   1 
ATOM   4330 C CE1   . PHE A 1 617 ? 150.496 151.894 119.720 1.00 144.28 ? 617 PHE A CE1   1 
ATOM   4331 C CE2   . PHE A 1 617 ? 150.857 149.903 120.988 1.00 144.96 ? 617 PHE A CE2   1 
ATOM   4332 C CZ    . PHE A 1 617 ? 151.253 151.172 120.619 1.00 144.40 ? 617 PHE A CZ    1 
ATOM   4333 N N     . ASP A 1 618 ? 148.624 146.519 118.379 1.00 134.89 ? 618 ASP A N     1 
ATOM   4334 C CA    . ASP A 1 618 ? 149.610 145.478 118.645 1.00 140.43 ? 618 ASP A CA    1 
ATOM   4335 C C     . ASP A 1 618 ? 150.213 144.936 117.356 1.00 140.07 ? 618 ASP A C     1 
ATOM   4336 O O     . ASP A 1 618 ? 151.430 144.745 117.267 1.00 139.85 ? 618 ASP A O     1 
ATOM   4337 C CB    . ASP A 1 618 ? 148.966 144.351 119.454 1.00 143.52 ? 618 ASP A CB    1 
ATOM   4338 C CG    . ASP A 1 618 ? 149.986 143.406 120.059 1.00 147.13 ? 618 ASP A CG    1 
ATOM   4339 O OD1   . ASP A 1 618 ? 151.188 143.743 120.055 1.00 148.71 ? 618 ASP A OD1   1 
ATOM   4340 O OD2   . ASP A 1 618 ? 149.585 142.325 120.540 1.00 146.64 ? 618 ASP A OD2   1 
ATOM   4341 N N     . ASP A 1 619 ? 149.383 144.684 116.343 1.00 140.37 ? 619 ASP A N     1 
ATOM   4342 C CA    . ASP A 1 619 ? 149.903 144.114 115.105 1.00 139.25 ? 619 ASP A CA    1 
ATOM   4343 C C     . ASP A 1 619 ? 150.379 145.163 114.107 1.00 133.43 ? 619 ASP A C     1 
ATOM   4344 O O     . ASP A 1 619 ? 151.078 144.810 113.151 1.00 129.56 ? 619 ASP A O     1 
ATOM   4345 C CB    . ASP A 1 619 ? 148.866 143.187 114.449 1.00 136.23 ? 619 ASP A CB    1 
ATOM   4346 C CG    . ASP A 1 619 ? 147.540 143.871 114.164 1.00 132.62 ? 619 ASP A CG    1 
ATOM   4347 O OD1   . ASP A 1 619 ? 147.508 145.100 113.972 1.00 132.14 ? 619 ASP A OD1   1 
ATOM   4348 O OD2   . ASP A 1 619 ? 146.513 143.161 114.132 1.00 128.74 ? 619 ASP A OD2   1 
ATOM   4349 N N     . LEU A 1 620 ? 150.027 146.437 114.297 1.00 133.93 ? 620 LEU A N     1 
ATOM   4350 C CA    . LEU A 1 620 ? 150.565 147.488 113.447 1.00 131.76 ? 620 LEU A CA    1 
ATOM   4351 C C     . LEU A 1 620 ? 151.860 148.077 113.984 1.00 135.29 ? 620 LEU A C     1 
ATOM   4352 O O     . LEU A 1 620 ? 152.612 148.682 113.214 1.00 135.28 ? 620 LEU A O     1 
ATOM   4353 C CB    . LEU A 1 620 ? 149.538 148.609 113.276 1.00 131.16 ? 620 LEU A CB    1 
ATOM   4354 C CG    . LEU A 1 620 ? 148.368 148.364 112.325 1.00 123.37 ? 620 LEU A CG    1 
ATOM   4355 C CD1   . LEU A 1 620 ? 147.406 149.536 112.371 1.00 115.82 ? 620 LEU A CD1   1 
ATOM   4356 C CD2   . LEU A 1 620 ? 148.870 148.134 110.910 1.00 117.77 ? 620 LEU A CD2   1 
ATOM   4357 N N     . PHE A 1 621 ? 152.136 147.934 115.283 1.00 137.01 ? 621 PHE A N     1 
ATOM   4358 C CA    . PHE A 1 621 ? 153.282 148.605 115.872 1.00 133.67 ? 621 PHE A CA    1 
ATOM   4359 C C     . PHE A 1 621 ? 154.162 147.734 116.756 1.00 139.84 ? 621 PHE A C     1 
ATOM   4360 O O     . PHE A 1 621 ? 155.260 148.177 117.111 1.00 144.14 ? 621 PHE A O     1 
ATOM   4361 C CB    . PHE A 1 621 ? 152.818 149.827 116.679 1.00 135.26 ? 621 PHE A CB    1 
ATOM   4362 C CG    . PHE A 1 621 ? 152.010 150.801 115.876 1.00 136.30 ? 621 PHE A CG    1 
ATOM   4363 C CD1   . PHE A 1 621 ? 152.599 151.532 114.860 1.00 133.67 ? 621 PHE A CD1   1 
ATOM   4364 C CD2   . PHE A 1 621 ? 150.660 150.978 116.125 1.00 136.48 ? 621 PHE A CD2   1 
ATOM   4365 C CE1   . PHE A 1 621 ? 151.862 152.423 114.111 1.00 130.06 ? 621 PHE A CE1   1 
ATOM   4366 C CE2   . PHE A 1 621 ? 149.916 151.873 115.380 1.00 135.28 ? 621 PHE A CE2   1 
ATOM   4367 C CZ    . PHE A 1 621 ? 150.520 152.597 114.372 1.00 132.24 ? 621 PHE A CZ    1 
ATOM   4368 N N     . CYS A 1 622 ? 153.736 146.528 117.125 1.00 142.44 ? 622 CYS A N     1 
ATOM   4369 C CA    . CYS A 1 622 ? 154.545 145.676 117.989 1.00 148.65 ? 622 CYS A CA    1 
ATOM   4370 C C     . CYS A 1 622 ? 154.892 144.336 117.359 1.00 151.23 ? 622 CYS A C     1 
ATOM   4371 O O     . CYS A 1 622 ? 156.057 143.923 117.397 1.00 151.81 ? 622 CYS A O     1 
ATOM   4372 C CB    . CYS A 1 622 ? 153.827 145.451 119.330 1.00 150.07 ? 622 CYS A CB    1 
ATOM   4373 S SG    . CYS A 1 622 ? 154.723 144.389 120.486 1.00 147.60 ? 622 CYS A SG    1 
ATOM   4374 N N     . GLU A 1 623 ? 153.914 143.643 116.778 1.00 149.30 ? 623 GLU A N     1 
ATOM   4375 C CA    . GLU A 1 623 ? 154.077 142.255 116.360 1.00 149.35 ? 623 GLU A CA    1 
ATOM   4376 C C     . GLU A 1 623 ? 154.671 142.124 114.961 1.00 150.73 ? 623 GLU A C     1 
ATOM   4377 O O     . GLU A 1 623 ? 155.653 141.399 114.767 1.00 155.72 ? 623 GLU A O     1 
ATOM   4378 C CB    . GLU A 1 623 ? 152.727 141.534 116.425 1.00 147.26 ? 623 GLU A CB    1 
ATOM   4379 C CG    . GLU A 1 623 ? 152.796 140.046 116.128 1.00 151.93 ? 623 GLU A CG    1 
ATOM   4380 C CD    . GLU A 1 623 ? 153.493 139.261 117.223 1.00 152.63 ? 623 GLU A CD    1 
ATOM   4381 O OE1   . GLU A 1 623 ? 153.596 139.774 118.358 1.00 149.91 ? 623 GLU A OE1   1 
ATOM   4382 O OE2   . GLU A 1 623 ? 153.939 138.127 116.949 1.00 152.36 ? 623 GLU A OE2   1 
ATOM   4383 N N     . SER A 1 624 ? 154.081 142.805 113.976 1.00 145.17 ? 624 SER A N     1 
ATOM   4384 C CA    . SER A 1 624 ? 154.531 142.641 112.598 1.00 142.80 ? 624 SER A CA    1 
ATOM   4385 C C     . SER A 1 624 ? 155.953 143.149 112.405 1.00 145.70 ? 624 SER A C     1 
ATOM   4386 O O     . SER A 1 624 ? 156.686 142.627 111.558 1.00 148.02 ? 624 SER A O     1 
ATOM   4387 C CB    . SER A 1 624 ? 153.577 143.353 111.640 1.00 137.10 ? 624 SER A CB    1 
ATOM   4388 O OG    . SER A 1 624 ? 153.949 143.126 110.292 1.00 135.81 ? 624 SER A OG    1 
ATOM   4389 N N     . ALA A 1 625 ? 156.362 144.163 113.170 1.00 145.30 ? 625 ALA A N     1 
ATOM   4390 C CA    . ALA A 1 625 ? 157.750 144.606 113.113 1.00 148.96 ? 625 ALA A CA    1 
ATOM   4391 C C     . ALA A 1 625 ? 158.696 143.499 113.561 1.00 154.80 ? 625 ALA A C     1 
ATOM   4392 O O     . ALA A 1 625 ? 159.738 143.264 112.933 1.00 158.96 ? 625 ALA A O     1 
ATOM   4393 C CB    . ALA A 1 625 ? 157.937 145.857 113.971 1.00 149.26 ? 625 ALA A CB    1 
ATOM   4394 N N     . LYS A 1 626 ? 158.344 142.800 114.643 1.00 154.92 ? 626 LYS A N     1 
ATOM   4395 C CA    . LYS A 1 626 ? 159.138 141.657 115.079 1.00 158.13 ? 626 LYS A CA    1 
ATOM   4396 C C     . LYS A 1 626 ? 159.122 140.549 114.036 1.00 159.55 ? 626 LYS A C     1 
ATOM   4397 O O     . LYS A 1 626 ? 160.123 139.850 113.848 1.00 163.03 ? 626 LYS A O     1 
ATOM   4398 C CB    . LYS A 1 626 ? 158.624 141.137 116.421 1.00 156.62 ? 626 LYS A CB    1 
ATOM   4399 C CG    . LYS A 1 626 ? 158.771 142.119 117.570 1.00 155.22 ? 626 LYS A CG    1 
ATOM   4400 C CD    . LYS A 1 626 ? 158.262 141.519 118.870 1.00 153.34 ? 626 LYS A CD    1 
ATOM   4401 C CE    . LYS A 1 626 ? 158.421 142.490 120.028 1.00 149.26 ? 626 LYS A CE    1 
ATOM   4402 N NZ    . LYS A 1 626 ? 157.948 141.901 121.311 1.00 145.90 ? 626 LYS A NZ    1 
ATOM   4403 N N     . THR A 1 627 ? 157.988 140.364 113.357 1.00 158.38 ? 627 THR A N     1 
ATOM   4404 C CA    . THR A 1 627 ? 157.916 139.356 112.303 1.00 157.81 ? 627 THR A CA    1 
ATOM   4405 C C     . THR A 1 627 ? 158.855 139.697 111.151 1.00 154.75 ? 627 THR A C     1 
ATOM   4406 O O     . THR A 1 627 ? 159.506 138.811 110.585 1.00 155.66 ? 627 THR A O     1 
ATOM   4407 C CB    . THR A 1 627 ? 156.477 139.223 111.803 1.00 153.90 ? 627 THR A CB    1 
ATOM   4408 O OG1   . THR A 1 627 ? 155.589 139.118 112.922 1.00 156.09 ? 627 THR A OG1   1 
ATOM   4409 C CG2   . THR A 1 627 ? 156.329 137.982 110.939 1.00 150.74 ? 627 THR A CG2   1 
ATOM   4410 N N     . ILE A 1 628 ? 158.930 140.978 110.787 1.00 150.64 ? 628 ILE A N     1 
ATOM   4411 C CA    . ILE A 1 628 ? 159.862 141.411 109.748 1.00 147.42 ? 628 ILE A CA    1 
ATOM   4412 C C     . ILE A 1 628 ? 161.299 141.181 110.196 1.00 152.83 ? 628 ILE A C     1 
ATOM   4413 O O     . ILE A 1 628 ? 162.125 140.643 109.449 1.00 153.73 ? 628 ILE A O     1 
ATOM   4414 C CB    . ILE A 1 628 ? 159.629 142.891 109.395 1.00 148.44 ? 628 ILE A CB    1 
ATOM   4415 C CG1   . ILE A 1 628 ? 158.211 143.115 108.877 1.00 145.54 ? 628 ILE A CG1   1 
ATOM   4416 C CG2   . ILE A 1 628 ? 160.651 143.363 108.370 1.00 149.00 ? 628 ILE A CG2   1 
ATOM   4417 C CD1   . ILE A 1 628 ? 157.886 144.573 108.629 1.00 141.27 ? 628 ILE A CD1   1 
ATOM   4418 N N     . ASN A 1 629 ? 161.619 141.588 111.426 1.00 157.59 ? 629 ASN A N     1 
ATOM   4419 C CA    . ASN A 1 629 ? 163.006 141.572 111.877 1.00 159.64 ? 629 ASN A CA    1 
ATOM   4420 C C     . ASN A 1 629 ? 163.507 140.170 112.202 1.00 162.09 ? 629 ASN A C     1 
ATOM   4421 O O     . ASN A 1 629 ? 164.718 139.926 112.154 1.00 163.20 ? 629 ASN A O     1 
ATOM   4422 C CB    . ASN A 1 629 ? 163.169 142.477 113.099 1.00 159.75 ? 629 ASN A CB    1 
ATOM   4423 C CG    . ASN A 1 629 ? 162.731 143.902 112.829 1.00 158.89 ? 629 ASN A CG    1 
ATOM   4424 O OD1   . ASN A 1 629 ? 162.767 144.370 111.691 1.00 156.85 ? 629 ASN A OD1   1 
ATOM   4425 N ND2   . ASN A 1 629 ? 162.313 144.600 113.877 1.00 160.02 ? 629 ASN A ND2   1 
ATOM   4426 N N     . SER A 1 630 ? 162.605 139.245 112.536 1.00 163.77 ? 630 SER A N     1 
ATOM   4427 C CA    . SER A 1 630 ? 163.027 137.931 113.012 1.00 165.55 ? 630 SER A CA    1 
ATOM   4428 C C     . SER A 1 630 ? 163.687 137.117 111.904 1.00 170.19 ? 630 SER A C     1 
ATOM   4429 O O     . SER A 1 630 ? 164.746 136.513 112.113 1.00 170.04 ? 630 SER A O     1 
ATOM   4430 C CB    . SER A 1 630 ? 161.830 137.178 113.593 1.00 165.68 ? 630 SER A CB    1 
ATOM   4431 O OG    . SER A 1 630 ? 160.801 137.031 112.630 1.00 165.31 ? 630 SER A OG    1 
ATOM   4432 N N     . HIS A 1 631 ? 163.082 137.089 110.719 1.00 172.48 ? 631 HIS A N     1 
ATOM   4433 C CA    . HIS A 1 631 ? 163.597 136.242 109.651 1.00 172.34 ? 631 HIS A CA    1 
ATOM   4434 C C     . HIS A 1 631 ? 163.560 136.961 108.308 1.00 170.78 ? 631 HIS A C     1 
ATOM   4435 O O     . HIS A 1 631 ? 162.482 137.344 107.834 1.00 167.83 ? 631 HIS A O     1 
ATOM   4436 C CB    . HIS A 1 631 ? 162.799 134.939 109.572 1.00 174.04 ? 631 HIS A CB    1 
ATOM   4437 C CG    . HIS A 1 631 ? 162.880 134.104 110.812 1.00 174.57 ? 631 HIS A CG    1 
ATOM   4438 N ND1   . HIS A 1 631 ? 163.881 133.180 111.023 1.00 171.89 ? 631 HIS A ND1   1 
ATOM   4439 C CD2   . HIS A 1 631 ? 162.085 134.054 111.907 1.00 173.13 ? 631 HIS A CD2   1 
ATOM   4440 C CE1   . HIS A 1 631 ? 163.699 132.597 112.194 1.00 167.70 ? 631 HIS A CE1   1 
ATOM   4441 N NE2   . HIS A 1 631 ? 162.616 133.109 112.751 1.00 168.75 ? 631 HIS A NE2   1 
ATOM   4442 N N     . PRO A 1 632 ? 164.713 137.162 107.666 1.00 171.08 ? 632 PRO A N     1 
ATOM   4443 C CA    . PRO A 1 632 ? 164.727 137.740 106.317 1.00 171.46 ? 632 PRO A CA    1 
ATOM   4444 C C     . PRO A 1 632 ? 164.429 136.741 105.211 1.00 173.68 ? 632 PRO A C     1 
ATOM   4445 O O     . PRO A 1 632 ? 164.424 137.130 104.038 1.00 173.32 ? 632 PRO A O     1 
ATOM   4446 C CB    . PRO A 1 632 ? 166.160 138.276 106.198 1.00 169.61 ? 632 PRO A CB    1 
ATOM   4447 C CG    . PRO A 1 632 ? 166.961 137.339 107.036 1.00 168.44 ? 632 PRO A CG    1 
ATOM   4448 C CD    . PRO A 1 632 ? 166.073 136.946 108.192 1.00 169.18 ? 632 PRO A CD    1 
ATOM   4449 N N     . GLN A 1 633 ? 164.191 135.470 105.551 1.00 173.94 ? 633 GLN A N     1 
ATOM   4450 C CA    . GLN A 1 633 ? 163.902 134.468 104.529 1.00 173.01 ? 633 GLN A CA    1 
ATOM   4451 C C     . GLN A 1 633 ? 162.613 134.792 103.785 1.00 176.76 ? 633 GLN A C     1 
ATOM   4452 O O     . GLN A 1 633 ? 162.536 134.627 102.561 1.00 177.96 ? 633 GLN A O     1 
ATOM   4453 C CB    . GLN A 1 633 ? 163.821 133.079 105.163 1.00 171.03 ? 633 GLN A CB    1 
ATOM   4454 C CG    . GLN A 1 633 ? 165.117 132.611 105.805 1.00 172.43 ? 633 GLN A CG    1 
ATOM   4455 C CD    . GLN A 1 633 ? 165.007 131.214 106.385 1.00 167.14 ? 633 GLN A CD    1 
ATOM   4456 O OE1   . GLN A 1 633 ? 163.939 130.602 106.362 1.00 161.86 ? 633 GLN A OE1   1 
ATOM   4457 N NE2   . GLN A 1 633 ? 166.114 130.702 106.909 1.00 166.79 ? 633 GLN A NE2   1 
ATOM   4458 N N     . ALA A 1 634 ? 161.587 135.249 104.506 1.00 177.92 ? 634 ALA A N     1 
ATOM   4459 C CA    . ALA A 1 634 ? 160.335 135.629 103.864 1.00 179.36 ? 634 ALA A CA    1 
ATOM   4460 C C     . ALA A 1 634 ? 160.499 136.828 102.940 1.00 181.32 ? 634 ALA A C     1 
ATOM   4461 O O     . ALA A 1 634 ? 159.667 137.026 102.049 1.00 180.73 ? 634 ALA A O     1 
ATOM   4462 C CB    . ALA A 1 634 ? 159.271 135.927 104.921 1.00 175.02 ? 634 ALA A CB    1 
ATOM   4463 N N     . LEU A 1 635 ? 161.547 137.625 103.130 1.00 180.70 ? 635 LEU A N     1 
ATOM   4464 C CA    . LEU A 1 635 ? 161.821 138.778 102.284 1.00 179.39 ? 635 LEU A CA    1 
ATOM   4465 C C     . LEU A 1 635 ? 162.754 138.454 101.125 1.00 180.30 ? 635 LEU A C     1 
ATOM   4466 O O     . LEU A 1 635 ? 163.122 139.363 100.374 1.00 180.29 ? 635 LEU A O     1 
ATOM   4467 C CB    . LEU A 1 635 ? 162.415 139.915 103.122 1.00 175.00 ? 635 LEU A CB    1 
ATOM   4468 C CG    . LEU A 1 635 ? 161.586 140.373 104.324 1.00 169.81 ? 635 LEU A CG    1 
ATOM   4469 C CD1   . LEU A 1 635 ? 162.278 141.515 105.052 1.00 162.56 ? 635 LEU A CD1   1 
ATOM   4470 C CD2   . LEU A 1 635 ? 160.185 140.777 103.890 1.00 165.09 ? 635 LEU A CD2   1 
ATOM   4471 N N     . SER A 1 636 ? 163.151 137.190 100.966 1.00 179.97 ? 636 SER A N     1 
ATOM   4472 C CA    . SER A 1 636 ? 164.037 136.789 99.883  1.00 176.68 ? 636 SER A CA    1 
ATOM   4473 C C     . SER A 1 636 ? 163.578 135.548 99.132  1.00 176.73 ? 636 SER A C     1 
ATOM   4474 O O     . SER A 1 636 ? 164.143 135.252 98.074  1.00 173.34 ? 636 SER A O     1 
ATOM   4475 C CB    . SER A 1 636 ? 165.459 136.546 100.413 1.00 171.81 ? 636 SER A CB    1 
ATOM   4476 O OG    . SER A 1 636 ? 165.469 135.524 101.396 1.00 171.50 ? 636 SER A OG    1 
ATOM   4477 N N     . SER A 1 637 ? 162.583 134.819 99.633  1.00 179.18 ? 637 SER A N     1 
ATOM   4478 C CA    . SER A 1 637 ? 162.095 133.621 98.961  1.00 178.50 ? 637 SER A CA    1 
ATOM   4479 C C     . SER A 1 637 ? 160.598 133.457 99.194  1.00 180.40 ? 637 SER A C     1 
ATOM   4480 O O     . SER A 1 637 ? 160.174 133.115 100.306 1.00 181.09 ? 637 SER A O     1 
ATOM   4481 C CB    . SER A 1 637 ? 162.855 132.384 99.445  1.00 176.08 ? 637 SER A CB    1 
ATOM   4482 O OG    . SER A 1 637 ? 162.792 132.261 100.856 1.00 174.43 ? 637 SER A OG    1 
ATOM   4483 N N     . PRO A 1 638 ? 159.767 133.702 98.178  1.00 181.49 ? 638 PRO A N     1 
ATOM   4484 C CA    . PRO A 1 638 ? 158.315 133.532 98.357  1.00 182.48 ? 638 PRO A CA    1 
ATOM   4485 C C     . PRO A 1 638 ? 157.900 132.105 98.675  1.00 181.07 ? 638 PRO A C     1 
ATOM   4486 O O     . PRO A 1 638 ? 156.817 131.904 99.242  1.00 180.43 ? 638 PRO A O     1 
ATOM   4487 C CB    . PRO A 1 638 ? 157.738 133.996 97.012  1.00 179.25 ? 638 PRO A CB    1 
ATOM   4488 C CG    . PRO A 1 638 ? 158.803 134.867 96.419  1.00 180.01 ? 638 PRO A CG    1 
ATOM   4489 C CD    . PRO A 1 638 ? 160.100 134.262 96.858  1.00 180.29 ? 638 PRO A CD    1 
ATOM   4490 N N     . GLU A 1 639 ? 158.721 131.110 98.327  1.00 180.66 ? 639 GLU A N     1 
ATOM   4491 C CA    . GLU A 1 639 ? 158.376 129.725 98.634  1.00 180.91 ? 639 GLU A CA    1 
ATOM   4492 C C     . GLU A 1 639 ? 158.269 129.508 100.138 1.00 180.43 ? 639 GLU A C     1 
ATOM   4493 O O     . GLU A 1 639 ? 157.344 128.837 100.612 1.00 177.90 ? 639 GLU A O     1 
ATOM   4494 C CB    . GLU A 1 639 ? 159.408 128.775 98.024  1.00 180.60 ? 639 GLU A CB    1 
ATOM   4495 C CG    . GLU A 1 639 ? 159.417 128.741 96.500  1.00 179.13 ? 639 GLU A CG    1 
ATOM   4496 C CD    . GLU A 1 639 ? 160.141 129.924 95.884  1.00 176.90 ? 639 GLU A CD    1 
ATOM   4497 O OE1   . GLU A 1 639 ? 160.979 130.539 96.578  1.00 177.83 ? 639 GLU A OE1   1 
ATOM   4498 O OE2   . GLU A 1 639 ? 159.872 130.240 94.706  1.00 173.04 ? 639 GLU A OE2   1 
ATOM   4499 N N     . ASP A 1 640 ? 159.206 130.066 100.905 1.00 182.14 ? 640 ASP A N     1 
ATOM   4500 C CA    . ASP A 1 640 ? 159.103 130.041 102.357 1.00 181.08 ? 640 ASP A CA    1 
ATOM   4501 C C     . ASP A 1 640 ? 158.079 131.038 102.882 1.00 179.48 ? 640 ASP A C     1 
ATOM   4502 O O     . ASP A 1 640 ? 157.539 130.834 103.975 1.00 178.89 ? 640 ASP A O     1 
ATOM   4503 C CB    . ASP A 1 640 ? 160.469 130.320 102.988 1.00 178.50 ? 640 ASP A CB    1 
ATOM   4504 C CG    . ASP A 1 640 ? 161.509 129.285 102.606 1.00 174.01 ? 640 ASP A CG    1 
ATOM   4505 O OD1   . ASP A 1 640 ? 161.139 128.105 102.430 1.00 172.70 ? 640 ASP A OD1   1 
ATOM   4506 O OD2   . ASP A 1 640 ? 162.697 129.651 102.481 1.00 170.37 ? 640 ASP A OD2   1 
ATOM   4507 N N     . LEU A 1 641 ? 157.806 132.108 102.131 1.00 179.74 ? 641 LEU A N     1 
ATOM   4508 C CA    . LEU A 1 641 ? 156.784 133.066 102.543 1.00 178.39 ? 641 LEU A CA    1 
ATOM   4509 C C     . LEU A 1 641 ? 155.401 132.428 102.547 1.00 176.96 ? 641 LEU A C     1 
ATOM   4510 O O     . LEU A 1 641 ? 154.563 132.754 103.397 1.00 174.52 ? 641 LEU A O     1 
ATOM   4511 C CB    . LEU A 1 641 ? 156.813 134.289 101.625 1.00 180.07 ? 641 LEU A CB    1 
ATOM   4512 C CG    . LEU A 1 641 ? 155.770 135.379 101.883 1.00 175.59 ? 641 LEU A CG    1 
ATOM   4513 C CD1   . LEU A 1 641 ? 155.896 135.920 103.298 1.00 170.34 ? 641 LEU A CD1   1 
ATOM   4514 C CD2   . LEU A 1 641 ? 155.904 136.499 100.864 1.00 170.39 ? 641 LEU A CD2   1 
ATOM   4515 N N     . VAL A 1 642 ? 155.140 131.525 101.600 1.00 179.15 ? 642 VAL A N     1 
ATOM   4516 C CA    . VAL A 1 642 ? 153.871 130.803 101.594 1.00 177.31 ? 642 VAL A CA    1 
ATOM   4517 C C     . VAL A 1 642 ? 153.736 129.955 102.853 1.00 178.38 ? 642 VAL A C     1 
ATOM   4518 O O     . VAL A 1 642 ? 152.669 129.907 103.478 1.00 176.01 ? 642 VAL A O     1 
ATOM   4519 C CB    . VAL A 1 642 ? 153.746 129.948 100.318 1.00 173.48 ? 642 VAL A CB    1 
ATOM   4520 C CG1   . VAL A 1 642 ? 152.480 129.105 100.361 1.00 171.31 ? 642 VAL A CG1   1 
ATOM   4521 C CG2   . VAL A 1 642 ? 153.755 130.835 99.083  1.00 169.29 ? 642 VAL A CG2   1 
ATOM   4522 N N     . LYS A 1 643 ? 154.816 129.276 103.246 1.00 180.05 ? 643 LYS A N     1 
ATOM   4523 C CA    . LYS A 1 643 ? 154.775 128.429 104.434 1.00 179.29 ? 643 LYS A CA    1 
ATOM   4524 C C     . LYS A 1 643 ? 154.670 129.247 105.716 1.00 179.77 ? 643 LYS A C     1 
ATOM   4525 O O     . LYS A 1 643 ? 154.044 128.799 106.683 1.00 178.97 ? 643 LYS A O     1 
ATOM   4526 C CB    . LYS A 1 643 ? 156.017 127.539 104.482 1.00 177.54 ? 643 LYS A CB    1 
ATOM   4527 C CG    . LYS A 1 643 ? 156.325 126.822 103.177 1.00 174.50 ? 643 LYS A CG    1 
ATOM   4528 C CD    . LYS A 1 643 ? 157.674 126.122 103.242 1.00 170.72 ? 643 LYS A CD    1 
ATOM   4529 C CE    . LYS A 1 643 ? 158.039 125.496 101.905 1.00 167.76 ? 643 LYS A CE    1 
ATOM   4530 N NZ    . LYS A 1 643 ? 159.385 124.858 101.942 1.00 162.67 ? 643 LYS A NZ    1 
ATOM   4531 N N     . SER A 1 644 ? 155.273 130.438 105.746 1.00 180.49 ? 644 SER A N     1 
ATOM   4532 C CA    . SER A 1 644 ? 155.354 131.199 106.991 1.00 175.33 ? 644 SER A CA    1 
ATOM   4533 C C     . SER A 1 644 ? 153.999 131.750 107.423 1.00 170.87 ? 644 SER A C     1 
ATOM   4534 O O     . SER A 1 644 ? 153.763 131.920 108.625 1.00 168.89 ? 644 SER A O     1 
ATOM   4535 C CB    . SER A 1 644 ? 156.368 132.333 106.846 1.00 172.65 ? 644 SER A CB    1 
ATOM   4536 O OG    . SER A 1 644 ? 156.052 133.163 105.743 1.00 172.36 ? 644 SER A OG    1 
ATOM   4537 N N     . GLN A 1 645 ? 153.107 132.036 106.472 1.00 168.69 ? 645 GLN A N     1 
ATOM   4538 C CA    . GLN A 1 645 ? 151.767 132.557 106.752 1.00 164.72 ? 645 GLN A CA    1 
ATOM   4539 C C     . GLN A 1 645 ? 151.846 133.884 107.519 1.00 159.98 ? 645 GLN A C     1 
ATOM   4540 O O     . GLN A 1 645 ? 151.483 133.997 108.692 1.00 157.52 ? 645 GLN A O     1 
ATOM   4541 C CB    . GLN A 1 645 ? 150.921 131.517 107.500 1.00 163.27 ? 645 GLN A CB    1 
ATOM   4542 C CG    . GLN A 1 645 ? 149.466 131.917 107.702 1.00 159.35 ? 645 GLN A CG    1 
ATOM   4543 C CD    . GLN A 1 645 ? 148.882 132.610 106.488 1.00 159.32 ? 645 GLN A CD    1 
ATOM   4544 O OE1   . GLN A 1 645 ? 148.782 133.837 106.449 1.00 158.64 ? 645 GLN A OE1   1 
ATOM   4545 N NE2   . GLN A 1 645 ? 148.492 131.827 105.489 1.00 158.50 ? 645 GLN A NE2   1 
ATOM   4546 N N     . LYS A 1 646 ? 152.367 134.893 106.812 1.00 154.82 ? 646 LYS A N     1 
ATOM   4547 C CA    . LYS A 1 646 ? 152.527 136.226 107.382 1.00 149.30 ? 646 LYS A CA    1 
ATOM   4548 C C     . LYS A 1 646 ? 152.175 137.331 106.389 1.00 143.43 ? 646 LYS A C     1 
ATOM   4549 O O     . LYS A 1 646 ? 152.597 138.478 106.578 1.00 142.88 ? 646 LYS A O     1 
ATOM   4550 C CB    . LYS A 1 646 ? 153.964 136.421 107.880 1.00 156.31 ? 646 LYS A CB    1 
ATOM   4551 C CG    . LYS A 1 646 ? 155.013 135.955 106.882 1.00 158.97 ? 646 LYS A CG    1 
ATOM   4552 C CD    . LYS A 1 646 ? 156.420 136.025 107.453 1.00 159.37 ? 646 LYS A CD    1 
ATOM   4553 C CE    . LYS A 1 646 ? 156.953 137.446 107.447 1.00 154.68 ? 646 LYS A CE    1 
ATOM   4554 N NZ    . LYS A 1 646 ? 158.337 137.512 107.993 1.00 155.80 ? 646 LYS A NZ    1 
ATOM   4555 N N     . GLN A 1 647 ? 151.419 137.014 105.338 1.00 143.54 ? 647 GLN A N     1 
ATOM   4556 C CA    . GLN A 1 647 ? 151.171 137.982 104.270 1.00 141.14 ? 647 GLN A CA    1 
ATOM   4557 C C     . GLN A 1 647 ? 150.369 139.209 104.698 1.00 129.97 ? 647 GLN A C     1 
ATOM   4558 O O     . GLN A 1 647 ? 150.781 140.330 104.352 1.00 127.36 ? 647 GLN A O     1 
ATOM   4559 C CB    . GLN A 1 647 ? 150.497 137.275 103.089 1.00 143.56 ? 647 GLN A CB    1 
ATOM   4560 C CG    . GLN A 1 647 ? 151.415 136.348 102.304 1.00 148.10 ? 647 GLN A CG    1 
ATOM   4561 C CD    . GLN A 1 647 ? 151.524 134.967 102.917 1.00 154.67 ? 647 GLN A CD    1 
ATOM   4562 O OE1   . GLN A 1 647 ? 152.328 134.735 103.819 1.00 160.58 ? 647 GLN A OE1   1 
ATOM   4563 N NE2   . GLN A 1 647 ? 150.715 134.038 102.423 1.00 153.54 ? 647 GLN A NE2   1 
ATOM   4564 N N     . PRO A 1 648 ? 149.233 139.094 105.403 1.00 121.21 ? 648 PRO A N     1 
ATOM   4565 C CA    . PRO A 1 648 ? 148.378 140.285 105.571 1.00 111.88 ? 648 PRO A CA    1 
ATOM   4566 C C     . PRO A 1 648 ? 148.997 141.382 106.419 1.00 116.48 ? 648 PRO A C     1 
ATOM   4567 O O     . PRO A 1 648 ? 148.866 142.566 106.077 1.00 121.03 ? 648 PRO A O     1 
ATOM   4568 C CB    . PRO A 1 648 ? 147.113 139.712 106.221 1.00 115.57 ? 648 PRO A CB    1 
ATOM   4569 C CG    . PRO A 1 648 ? 147.578 138.502 106.930 1.00 124.57 ? 648 PRO A CG    1 
ATOM   4570 C CD    . PRO A 1 648 ? 148.636 137.911 106.049 1.00 128.74 ? 648 PRO A CD    1 
ATOM   4571 N N     . LEU A 1 649 ? 149.654 141.030 107.527 1.00 120.01 ? 649 LEU A N     1 
ATOM   4572 C CA    . LEU A 1 649 ? 150.296 142.047 108.354 1.00 117.49 ? 649 LEU A CA    1 
ATOM   4573 C C     . LEU A 1 649 ? 151.388 142.767 107.577 1.00 119.20 ? 649 LEU A C     1 
ATOM   4574 O O     . LEU A 1 649 ? 151.515 143.995 107.656 1.00 121.05 ? 649 LEU A O     1 
ATOM   4575 C CB    . LEU A 1 649 ? 150.876 141.416 109.623 1.00 116.54 ? 649 LEU A CB    1 
ATOM   4576 C CG    . LEU A 1 649 ? 149.938 140.960 110.744 1.00 116.76 ? 649 LEU A CG    1 
ATOM   4577 C CD1   . LEU A 1 649 ? 149.188 139.687 110.382 1.00 110.14 ? 649 LEU A CD1   1 
ATOM   4578 C CD2   . LEU A 1 649 ? 150.720 140.770 112.035 1.00 125.96 ? 649 LEU A CD2   1 
ATOM   4579 N N     . LEU A 1 650 ? 152.182 142.017 106.814 1.00 118.01 ? 650 LEU A N     1 
ATOM   4580 C CA    . LEU A 1 650 ? 153.229 142.627 106.004 1.00 116.24 ? 650 LEU A CA    1 
ATOM   4581 C C     . LEU A 1 650 ? 152.640 143.546 104.940 1.00 118.89 ? 650 LEU A C     1 
ATOM   4582 O O     . LEU A 1 650 ? 153.158 144.643 104.698 1.00 120.33 ? 650 LEU A O     1 
ATOM   4583 C CB    . LEU A 1 650 ? 154.085 141.532 105.370 1.00 120.26 ? 650 LEU A CB    1 
ATOM   4584 C CG    . LEU A 1 650 ? 155.524 141.886 105.013 1.00 126.60 ? 650 LEU A CG    1 
ATOM   4585 C CD1   . LEU A 1 650 ? 156.105 142.815 106.049 1.00 125.32 ? 650 LEU A CD1   1 
ATOM   4586 C CD2   . LEU A 1 650 ? 156.359 140.620 104.907 1.00 135.57 ? 650 LEU A CD2   1 
ATOM   4587 N N     . GLN A 1 651 ? 151.551 143.117 104.297 1.00 122.74 ? 651 GLN A N     1 
ATOM   4588 C CA    . GLN A 1 651 ? 150.924 143.945 103.271 1.00 118.59 ? 651 GLN A CA    1 
ATOM   4589 C C     . GLN A 1 651 ? 150.378 145.239 103.860 1.00 115.54 ? 651 GLN A C     1 
ATOM   4590 O O     . GLN A 1 651 ? 150.539 146.313 103.268 1.00 117.30 ? 651 GLN A O     1 
ATOM   4591 C CB    . GLN A 1 651 ? 149.809 143.168 102.571 1.00 119.48 ? 651 GLN A CB    1 
ATOM   4592 C CG    . GLN A 1 651 ? 149.073 143.975 101.513 1.00 114.78 ? 651 GLN A CG    1 
ATOM   4593 C CD    . GLN A 1 651 ? 147.978 143.181 100.832 1.00 121.35 ? 651 GLN A CD    1 
ATOM   4594 O OE1   . GLN A 1 651 ? 148.061 142.887 99.640  1.00 126.89 ? 651 GLN A OE1   1 
ATOM   4595 N NE2   . GLN A 1 651 ? 146.943 142.832 101.585 1.00 120.06 ? 651 GLN A NE2   1 
ATOM   4596 N N     . THR A 1 652 ? 149.729 145.162 105.024 1.00 113.95 ? 652 THR A N     1 
ATOM   4597 C CA    . THR A 1 652 ? 149.169 146.371 105.616 1.00 107.78 ? 652 THR A CA    1 
ATOM   4598 C C     . THR A 1 652 ? 150.240 147.256 106.245 1.00 114.00 ? 652 THR A C     1 
ATOM   4599 O O     . THR A 1 652 ? 150.010 148.459 106.407 1.00 117.49 ? 652 THR A O     1 
ATOM   4600 C CB    . THR A 1 652 ? 148.095 146.020 106.649 1.00 103.56 ? 652 THR A CB    1 
ATOM   4601 O OG1   . THR A 1 652 ? 147.341 147.195 106.968 1.00 95.21  ? 652 THR A OG1   1 
ATOM   4602 C CG2   . THR A 1 652 ? 148.719 145.468 107.922 1.00 111.51 ? 652 THR A CG2   1 
ATOM   4603 N N     . MET A 1 653 ? 151.402 146.697 106.597 1.00 115.25 ? 653 MET A N     1 
ATOM   4604 C CA    . MET A 1 653 ? 152.510 147.537 107.039 1.00 114.18 ? 653 MET A CA    1 
ATOM   4605 C C     . MET A 1 653 ? 153.166 148.238 105.859 1.00 111.55 ? 653 MET A C     1 
ATOM   4606 O O     . MET A 1 653 ? 153.622 149.380 105.983 1.00 109.95 ? 653 MET A O     1 
ATOM   4607 C CB    . MET A 1 653 ? 153.538 146.706 107.802 1.00 115.20 ? 653 MET A CB    1 
ATOM   4608 C CG    . MET A 1 653 ? 154.504 147.537 108.625 1.00 114.42 ? 653 MET A CG    1 
ATOM   4609 S SD    . MET A 1 653 ? 153.693 148.254 110.062 1.00 121.97 ? 653 MET A SD    1 
ATOM   4610 C CE    . MET A 1 653 ? 152.897 146.797 110.726 1.00 129.77 ? 653 MET A CE    1 
ATOM   4611 N N     . ARG A 1 654 ? 153.242 147.559 104.711 1.00 114.72 ? 654 ARG A N     1 
ATOM   4612 C CA    . ARG A 1 654 ? 153.735 148.203 103.499 1.00 113.64 ? 654 ARG A CA    1 
ATOM   4613 C C     . ARG A 1 654 ? 152.873 149.400 103.122 1.00 111.77 ? 654 ARG A C     1 
ATOM   4614 O O     . ARG A 1 654 ? 153.384 150.395 102.595 1.00 114.96 ? 654 ARG A O     1 
ATOM   4615 C CB    . ARG A 1 654 ? 153.781 147.192 102.354 1.00 116.51 ? 654 ARG A CB    1 
ATOM   4616 C CG    . ARG A 1 654 ? 154.512 147.672 101.116 1.00 121.13 ? 654 ARG A CG    1 
ATOM   4617 C CD    . ARG A 1 654 ? 153.861 147.119 99.865  1.00 126.78 ? 654 ARG A CD    1 
ATOM   4618 N NE    . ARG A 1 654 ? 152.524 147.668 99.676  1.00 126.08 ? 654 ARG A NE    1 
ATOM   4619 C CZ    . ARG A 1 654 ? 151.606 147.152 98.871  1.00 121.96 ? 654 ARG A CZ    1 
ATOM   4620 N NH1   . ARG A 1 654 ? 151.838 146.055 98.170  1.00 114.02 ? 654 ARG A NH1   1 
ATOM   4621 N NH2   . ARG A 1 654 ? 150.421 147.747 98.774  1.00 126.77 ? 654 ARG A NH2   1 
ATOM   4622 N N     . GLY A 1 655 ? 151.573 149.325 103.387 1.00 108.19 ? 655 GLY A N     1 
ATOM   4623 C CA    . GLY A 1 655 ? 150.685 150.448 103.193 1.00 99.97  ? 655 GLY A CA    1 
ATOM   4624 C C     . GLY A 1 655 ? 150.321 150.685 101.741 1.00 97.80  ? 655 GLY A C     1 
ATOM   4625 O O     . GLY A 1 655 ? 150.637 149.906 100.839 1.00 103.72 ? 655 GLY A O     1 
ATOM   4626 N N     . VAL A 1 656 ? 149.620 151.801 101.527 1.00 98.37  ? 656 VAL A N     1 
ATOM   4627 C CA    . VAL A 1 656 ? 149.311 152.242 100.172 1.00 100.18 ? 656 VAL A CA    1 
ATOM   4628 C C     . VAL A 1 656 ? 150.595 152.505 99.404  1.00 105.84 ? 656 VAL A C     1 
ATOM   4629 O O     . VAL A 1 656 ? 150.663 152.288 98.188  1.00 107.77 ? 656 VAL A O     1 
ATOM   4630 C CB    . VAL A 1 656 ? 148.409 153.493 100.212 1.00 100.38 ? 656 VAL A CB    1 
ATOM   4631 C CG1   . VAL A 1 656 ? 147.901 153.836 98.818  1.00 100.33 ? 656 VAL A CG1   1 
ATOM   4632 C CG2   . VAL A 1 656 ? 147.251 153.290 101.177 1.00 93.20  ? 656 VAL A CG2   1 
ATOM   4633 N N     . LEU A 1 657 ? 151.630 152.970 100.095 1.00 107.70 ? 657 LEU A N     1 
ATOM   4634 C CA    . LEU A 1 657 ? 152.924 153.183 99.472  1.00 118.65 ? 657 LEU A CA    1 
ATOM   4635 C C     . LEU A 1 657 ? 153.589 151.853 99.139  1.00 130.84 ? 657 LEU A C     1 
ATOM   4636 O O     . LEU A 1 657 ? 153.346 150.829 99.783  1.00 131.73 ? 657 LEU A O     1 
ATOM   4637 C CB    . LEU A 1 657 ? 153.840 153.990 100.394 1.00 118.00 ? 657 LEU A CB    1 
ATOM   4638 C CG    . LEU A 1 657 ? 153.440 155.410 100.805 1.00 115.38 ? 657 LEU A CG    1 
ATOM   4639 C CD1   . LEU A 1 657 ? 152.431 155.403 101.944 1.00 101.72 ? 657 LEU A CD1   1 
ATOM   4640 C CD2   . LEU A 1 657 ? 154.675 156.210 101.188 1.00 127.86 ? 657 LEU A CD2   1 
ATOM   4641 N N     . THR A 1 658 ? 154.435 151.877 98.112  1.00 138.46 ? 658 THR A N     1 
ATOM   4642 C CA    . THR A 1 658 ? 155.329 150.768 97.814  1.00 145.17 ? 658 THR A CA    1 
ATOM   4643 C C     . THR A 1 658 ? 156.779 151.076 98.145  1.00 147.81 ? 658 THR A C     1 
ATOM   4644 O O     . THR A 1 658 ? 157.543 150.155 98.441  1.00 154.57 ? 658 THR A O     1 
ATOM   4645 C CB    . THR A 1 658 ? 155.224 150.371 96.334  1.00 148.31 ? 658 THR A CB    1 
ATOM   4646 O OG1   . THR A 1 658 ? 156.202 149.367 96.033  1.00 149.89 ? 658 THR A OG1   1 
ATOM   4647 C CG2   . THR A 1 658 ? 155.443 151.579 95.433  1.00 146.70 ? 658 THR A CG2   1 
ATOM   4648 N N     . GLU A 1 659 ? 157.166 152.346 98.102  1.00 145.11 ? 659 GLU A N     1 
ATOM   4649 C CA    . GLU A 1 659 ? 158.495 152.778 98.493  1.00 153.07 ? 659 GLU A CA    1 
ATOM   4650 C C     . GLU A 1 659 ? 158.532 153.113 99.982  1.00 153.83 ? 659 GLU A C     1 
ATOM   4651 O O     . GLU A 1 659 ? 157.506 153.380 100.613 1.00 148.95 ? 659 GLU A O     1 
ATOM   4652 C CB    . GLU A 1 659 ? 158.930 153.993 97.670  1.00 153.16 ? 659 GLU A CB    1 
ATOM   4653 C CG    . GLU A 1 659 ? 158.080 155.246 97.879  1.00 153.06 ? 659 GLU A CG    1 
ATOM   4654 C CD    . GLU A 1 659 ? 156.850 155.294 96.987  1.00 152.21 ? 659 GLU A CD    1 
ATOM   4655 O OE1   . GLU A 1 659 ? 155.834 154.648 97.321  1.00 147.96 ? 659 GLU A OE1   1 
ATOM   4656 O OE2   . GLU A 1 659 ? 156.900 155.983 95.946  1.00 152.61 ? 659 GLU A OE2   1 
ATOM   4657 N N     . ARG A 1 660 ? 159.736 153.092 100.539 1.00 156.86 ? 660 ARG A N     1 
ATOM   4658 C CA    . ARG A 1 660 ? 159.919 153.486 101.930 1.00 152.77 ? 660 ARG A CA    1 
ATOM   4659 C C     . ARG A 1 660 ? 159.619 154.973 102.086 1.00 147.86 ? 660 ARG A C     1 
ATOM   4660 O O     . ARG A 1 660 ? 160.051 155.776 101.250 1.00 147.28 ? 660 ARG A O     1 
ATOM   4661 C CB    . ARG A 1 660 ? 161.343 153.184 102.387 1.00 153.67 ? 660 ARG A CB    1 
ATOM   4662 C CG    . ARG A 1 660 ? 161.693 151.709 102.385 1.00 154.62 ? 660 ARG A CG    1 
ATOM   4663 C CD    . ARG A 1 660 ? 161.128 151.008 103.607 1.00 150.70 ? 660 ARG A CD    1 
ATOM   4664 N NE    . ARG A 1 660 ? 161.861 151.353 104.820 1.00 154.85 ? 660 ARG A NE    1 
ATOM   4665 C CZ    . ARG A 1 660 ? 162.966 150.741 105.223 1.00 157.67 ? 660 ARG A CZ    1 
ATOM   4666 N NH1   . ARG A 1 660 ? 163.496 149.746 104.531 1.00 157.17 ? 660 ARG A NH1   1 
ATOM   4667 N NH2   . ARG A 1 660 ? 163.554 151.137 106.348 1.00 159.50 ? 660 ARG A NH2   1 
ATOM   4668 N N     . PRO A 1 661 ? 158.877 155.377 103.117 1.00 143.17 ? 661 PRO A N     1 
ATOM   4669 C CA    . PRO A 1 661 ? 158.607 156.807 103.310 1.00 143.29 ? 661 PRO A CA    1 
ATOM   4670 C C     . PRO A 1 661 ? 159.896 157.590 103.515 1.00 144.18 ? 661 PRO A C     1 
ATOM   4671 O O     . PRO A 1 661 ? 160.828 157.129 104.180 1.00 143.21 ? 661 PRO A O     1 
ATOM   4672 C CB    . PRO A 1 661 ? 157.717 156.836 104.558 1.00 135.23 ? 661 PRO A CB    1 
ATOM   4673 C CG    . PRO A 1 661 ? 157.974 155.533 105.248 1.00 136.15 ? 661 PRO A CG    1 
ATOM   4674 C CD    . PRO A 1 661 ? 158.252 154.546 104.159 1.00 138.29 ? 661 PRO A CD    1 
ATOM   4675 N N     . GLN A 1 662 ? 159.941 158.787 102.934 1.00 142.10 ? 662 GLN A N     1 
ATOM   4676 C CA    . GLN A 1 662 ? 161.139 159.618 102.941 1.00 140.54 ? 662 GLN A CA    1 
ATOM   4677 C C     . GLN A 1 662 ? 161.100 160.723 103.987 1.00 134.07 ? 662 GLN A C     1 
ATOM   4678 O O     . GLN A 1 662 ? 162.100 160.953 104.673 1.00 131.99 ? 662 GLN A O     1 
ATOM   4679 C CB    . GLN A 1 662 ? 161.356 160.239 101.557 1.00 140.43 ? 662 GLN A CB    1 
ATOM   4680 C CG    . GLN A 1 662 ? 161.497 159.223 100.434 1.00 142.47 ? 662 GLN A CG    1 
ATOM   4681 C CD    . GLN A 1 662 ? 162.780 158.421 100.530 1.00 145.14 ? 662 GLN A CD    1 
ATOM   4682 O OE1   . GLN A 1 662 ? 163.875 158.981 100.574 1.00 140.92 ? 662 GLN A OE1   1 
ATOM   4683 N NE2   . GLN A 1 662 ? 162.650 157.100 100.567 1.00 149.26 ? 662 GLN A NE2   1 
ATOM   4684 N N     . THR A 1 663 ? 159.969 161.414 104.128 1.00 128.20 ? 663 THR A N     1 
ATOM   4685 C CA    . THR A 1 663 ? 159.845 162.529 105.056 1.00 124.05 ? 663 THR A CA    1 
ATOM   4686 C C     . THR A 1 663 ? 158.534 162.396 105.818 1.00 114.63 ? 663 THR A C     1 
ATOM   4687 O O     . THR A 1 663 ? 157.734 161.491 105.570 1.00 111.61 ? 663 THR A O     1 
ATOM   4688 C CB    . THR A 1 663 ? 159.909 163.878 104.327 1.00 129.91 ? 663 THR A CB    1 
ATOM   4689 O OG1   . THR A 1 663 ? 158.921 163.908 103.289 1.00 128.47 ? 663 THR A OG1   1 
ATOM   4690 C CG2   . THR A 1 663 ? 161.288 164.102 103.720 1.00 131.20 ? 663 THR A CG2   1 
ATOM   4691 N N     . TRP A 1 664 ? 158.321 163.314 106.764 1.00 118.48 ? 664 TRP A N     1 
ATOM   4692 C CA    . TRP A 1 664 ? 157.080 163.319 107.533 1.00 117.75 ? 664 TRP A CA    1 
ATOM   4693 C C     . TRP A 1 664 ? 155.875 163.618 106.648 1.00 114.90 ? 664 TRP A C     1 
ATOM   4694 O O     . TRP A 1 664 ? 154.821 162.984 106.787 1.00 114.88 ? 664 TRP A O     1 
ATOM   4695 C CB    . TRP A 1 664 ? 157.176 164.336 108.669 1.00 115.35 ? 664 TRP A CB    1 
ATOM   4696 C CG    . TRP A 1 664 ? 155.887 164.540 109.386 1.00 111.22 ? 664 TRP A CG    1 
ATOM   4697 C CD1   . TRP A 1 664 ? 154.995 165.553 109.195 1.00 113.31 ? 664 TRP A CD1   1 
ATOM   4698 C CD2   . TRP A 1 664 ? 155.335 163.707 110.409 1.00 112.80 ? 664 TRP A CD2   1 
ATOM   4699 N NE1   . TRP A 1 664 ? 153.923 165.404 110.039 1.00 116.78 ? 664 TRP A NE1   1 
ATOM   4700 C CE2   . TRP A 1 664 ? 154.108 164.277 110.795 1.00 116.62 ? 664 TRP A CE2   1 
ATOM   4701 C CE3   . TRP A 1 664 ? 155.761 162.534 111.038 1.00 118.33 ? 664 TRP A CE3   1 
ATOM   4702 C CZ2   . TRP A 1 664 ? 153.302 163.717 111.782 1.00 122.38 ? 664 TRP A CZ2   1 
ATOM   4703 C CZ3   . TRP A 1 664 ? 154.960 161.978 112.017 1.00 124.71 ? 664 TRP A CZ3   1 
ATOM   4704 C CH2   . TRP A 1 664 ? 153.744 162.570 112.379 1.00 126.88 ? 664 TRP A CH2   1 
ATOM   4705 N N     . GLN A 1 665 ? 156.008 164.583 105.735 1.00 116.30 ? 665 GLN A N     1 
ATOM   4706 C CA    . GLN A 1 665 ? 154.910 164.921 104.838 1.00 117.43 ? 665 GLN A CA    1 
ATOM   4707 C C     . GLN A 1 665 ? 154.593 163.798 103.860 1.00 114.63 ? 665 GLN A C     1 
ATOM   4708 O O     . GLN A 1 665 ? 153.496 163.778 103.294 1.00 111.54 ? 665 GLN A O     1 
ATOM   4709 C CB    . GLN A 1 665 ? 155.228 166.207 104.070 1.00 124.35 ? 665 GLN A CB    1 
ATOM   4710 C CG    . GLN A 1 665 ? 156.530 166.175 103.285 1.00 127.28 ? 665 GLN A CG    1 
ATOM   4711 C CD    . GLN A 1 665 ? 157.693 166.786 104.046 1.00 130.54 ? 665 GLN A CD    1 
ATOM   4712 O OE1   . GLN A 1 665 ? 157.661 166.895 105.272 1.00 129.54 ? 665 GLN A OE1   1 
ATOM   4713 N NE2   . GLN A 1 665 ? 158.724 167.198 103.318 1.00 133.63 ? 665 GLN A NE2   1 
ATOM   4714 N N     . ASP A 1 666 ? 155.528 162.876 103.641 1.00 114.88 ? 666 ASP A N     1 
ATOM   4715 C CA    . ASP A 1 666 ? 155.277 161.696 102.824 1.00 113.38 ? 666 ASP A CA    1 
ATOM   4716 C C     . ASP A 1 666 ? 154.739 160.539 103.656 1.00 104.57 ? 666 ASP A C     1 
ATOM   4717 O O     . ASP A 1 666 ? 153.885 159.780 103.188 1.00 103.81 ? 666 ASP A O     1 
ATOM   4718 C CB    . ASP A 1 666 ? 156.564 161.273 102.109 1.00 126.41 ? 666 ASP A CB    1 
ATOM   4719 C CG    . ASP A 1 666 ? 156.343 160.144 101.121 1.00 129.80 ? 666 ASP A CG    1 
ATOM   4720 O OD1   . ASP A 1 666 ? 155.189 159.941 100.689 1.00 127.58 ? 666 ASP A OD1   1 
ATOM   4721 O OD2   . ASP A 1 666 ? 157.328 159.456 100.778 1.00 132.49 ? 666 ASP A OD2   1 
ATOM   4722 N N     . CYS A 1 667 ? 155.230 160.398 104.888 1.00 106.06 ? 667 CYS A N     1 
ATOM   4723 C CA    . CYS A 1 667 ? 154.768 159.336 105.774 1.00 96.00  ? 667 CYS A CA    1 
ATOM   4724 C C     . CYS A 1 667 ? 153.340 159.574 106.249 1.00 94.07  ? 667 CYS A C     1 
ATOM   4725 O O     . CYS A 1 667 ? 152.624 158.614 106.557 1.00 95.52  ? 667 CYS A O     1 
ATOM   4726 C CB    . CYS A 1 667 ? 155.715 159.212 106.967 1.00 99.84  ? 667 CYS A CB    1 
ATOM   4727 S SG    . CYS A 1 667 ? 155.125 158.172 108.314 1.00 113.89 ? 667 CYS A SG    1 
ATOM   4728 N N     . VAL A 1 668 ? 152.908 160.837 106.315 1.00 99.54  ? 668 VAL A N     1 
ATOM   4729 C CA    . VAL A 1 668 ? 151.560 161.143 106.782 1.00 100.02 ? 668 VAL A CA    1 
ATOM   4730 C C     . VAL A 1 668 ? 150.498 160.560 105.859 1.00 100.10 ? 668 VAL A C     1 
ATOM   4731 O O     . VAL A 1 668 ? 149.362 160.333 106.289 1.00 103.70 ? 668 VAL A O     1 
ATOM   4732 C CB    . VAL A 1 668 ? 151.382 162.670 106.941 1.00 108.41 ? 668 VAL A CB    1 
ATOM   4733 C CG1   . VAL A 1 668 ? 151.314 163.352 105.584 1.00 111.61 ? 668 VAL A CG1   1 
ATOM   4734 C CG2   . VAL A 1 668 ? 150.146 162.984 107.770 1.00 111.93 ? 668 VAL A CG2   1 
ATOM   4735 N N     . LEU A 1 669 ? 150.840 160.305 104.593 1.00 99.82  ? 669 LEU A N     1 
ATOM   4736 C CA    . LEU A 1 669 ? 149.887 159.688 103.677 1.00 94.70  ? 669 LEU A CA    1 
ATOM   4737 C C     . LEU A 1 669 ? 149.507 158.286 104.131 1.00 86.42  ? 669 LEU A C     1 
ATOM   4738 O O     . LEU A 1 669 ? 148.360 157.865 103.947 1.00 85.22  ? 669 LEU A O     1 
ATOM   4739 C CB    . LEU A 1 669 ? 150.471 159.659 102.262 1.00 98.88  ? 669 LEU A CB    1 
ATOM   4740 C CG    . LEU A 1 669 ? 149.596 159.220 101.084 1.00 100.13 ? 669 LEU A CG    1 
ATOM   4741 C CD1   . LEU A 1 669 ? 150.026 159.948 99.822  1.00 88.94  ? 669 LEU A CD1   1 
ATOM   4742 C CD2   . LEU A 1 669 ? 149.662 157.715 100.864 1.00 102.56 ? 669 LEU A CD2   1 
ATOM   4743 N N     . TRP A 1 670 ? 150.454 157.556 104.725 1.00 89.54  ? 670 TRP A N     1 
ATOM   4744 C CA    . TRP A 1 670 ? 150.200 156.179 105.135 1.00 93.96  ? 670 TRP A CA    1 
ATOM   4745 C C     . TRP A 1 670 ? 149.110 156.106 106.195 1.00 90.11  ? 670 TRP A C     1 
ATOM   4746 O O     . TRP A 1 670 ? 148.291 155.180 106.189 1.00 94.56  ? 670 TRP A O     1 
ATOM   4747 C CB    . TRP A 1 670 ? 151.495 155.546 105.650 1.00 102.44 ? 670 TRP A CB    1 
ATOM   4748 C CG    . TRP A 1 670 ? 151.339 154.137 106.139 1.00 109.34 ? 670 TRP A CG    1 
ATOM   4749 C CD1   . TRP A 1 670 ? 151.522 152.996 105.416 1.00 111.72 ? 670 TRP A CD1   1 
ATOM   4750 C CD2   . TRP A 1 670 ? 150.974 153.719 107.462 1.00 113.56 ? 670 TRP A CD2   1 
ATOM   4751 N NE1   . TRP A 1 670 ? 151.291 151.894 106.203 1.00 115.46 ? 670 TRP A NE1   1 
ATOM   4752 C CE2   . TRP A 1 670 ? 150.953 152.311 107.464 1.00 112.29 ? 670 TRP A CE2   1 
ATOM   4753 C CE3   . TRP A 1 670 ? 150.661 154.400 108.642 1.00 116.27 ? 670 TRP A CE3   1 
ATOM   4754 C CZ2   . TRP A 1 670 ? 150.632 151.571 108.599 1.00 111.41 ? 670 TRP A CZ2   1 
ATOM   4755 C CZ3   . TRP A 1 670 ? 150.343 153.663 109.769 1.00 118.77 ? 670 TRP A CZ3   1 
ATOM   4756 C CH2   . TRP A 1 670 ? 150.331 152.264 109.738 1.00 117.36 ? 670 TRP A CH2   1 
ATOM   4757 N N     . ALA A 1 671 ? 149.089 157.066 107.121 1.00 86.31  ? 671 ALA A N     1 
ATOM   4758 C CA    . ALA A 1 671 ? 148.121 157.023 108.211 1.00 90.74  ? 671 ALA A CA    1 
ATOM   4759 C C     . ALA A 1 671 ? 146.693 157.105 107.686 1.00 95.45  ? 671 ALA A C     1 
ATOM   4760 O O     . ALA A 1 671 ? 145.850 156.260 108.011 1.00 98.80  ? 671 ALA A O     1 
ATOM   4761 C CB    . ALA A 1 671 ? 148.398 158.155 109.201 1.00 107.86 ? 671 ALA A CB    1 
ATOM   4762 N N     . PHE A 1 672 ? 146.400 158.104 106.853 1.00 100.20 ? 672 PHE A N     1 
ATOM   4763 C CA    . PHE A 1 672 ? 145.044 158.214 106.330 1.00 98.61  ? 672 PHE A CA    1 
ATOM   4764 C C     . PHE A 1 672 ? 144.763 157.200 105.228 1.00 96.58  ? 672 PHE A C     1 
ATOM   4765 O O     . PHE A 1 672 ? 143.595 156.879 104.992 1.00 90.94  ? 672 PHE A O     1 
ATOM   4766 C CB    . PHE A 1 672 ? 144.766 159.642 105.845 1.00 102.96 ? 672 PHE A CB    1 
ATOM   4767 C CG    . PHE A 1 672 ? 145.015 159.857 104.382 1.00 103.60 ? 672 PHE A CG    1 
ATOM   4768 C CD1   . PHE A 1 672 ? 146.286 160.150 103.920 1.00 108.13 ? 672 PHE A CD1   1 
ATOM   4769 C CD2   . PHE A 1 672 ? 143.972 159.798 103.473 1.00 98.18  ? 672 PHE A CD2   1 
ATOM   4770 C CE1   . PHE A 1 672 ? 146.518 160.359 102.576 1.00 110.28 ? 672 PHE A CE1   1 
ATOM   4771 C CE2   . PHE A 1 672 ? 144.197 160.005 102.130 1.00 107.97 ? 672 PHE A CE2   1 
ATOM   4772 C CZ    . PHE A 1 672 ? 145.473 160.287 101.680 1.00 113.57 ? 672 PHE A CZ    1 
ATOM   4773 N N     . GLY A 1 673 ? 145.795 156.652 104.580 1.00 99.36  ? 673 GLY A N     1 
ATOM   4774 C CA    . GLY A 1 673 ? 145.570 155.515 103.703 1.00 90.51  ? 673 GLY A CA    1 
ATOM   4775 C C     . GLY A 1 673 ? 145.082 154.297 104.463 1.00 84.64  ? 673 GLY A C     1 
ATOM   4776 O O     . GLY A 1 673 ? 144.126 153.634 104.051 1.00 92.80  ? 673 GLY A O     1 
ATOM   4777 N N     . HIS A 1 674 ? 145.719 153.999 105.597 1.00 78.09  ? 674 HIS A N     1 
ATOM   4778 C CA    . HIS A 1 674 ? 145.227 152.933 106.459 1.00 81.41  ? 674 HIS A CA    1 
ATOM   4779 C C     . HIS A 1 674 ? 143.869 153.276 107.054 1.00 81.92  ? 674 HIS A C     1 
ATOM   4780 O O     . HIS A 1 674 ? 143.054 152.379 107.286 1.00 89.96  ? 674 HIS A O     1 
ATOM   4781 C CB    . HIS A 1 674 ? 146.230 152.640 107.572 1.00 89.26  ? 674 HIS A CB    1 
ATOM   4782 C CG    . HIS A 1 674 ? 145.749 151.627 108.562 1.00 85.07  ? 674 HIS A CG    1 
ATOM   4783 N ND1   . HIS A 1 674 ? 145.065 151.973 109.707 1.00 89.10  ? 674 HIS A ND1   1 
ATOM   4784 C CD2   . HIS A 1 674 ? 145.849 150.278 108.577 1.00 84.85  ? 674 HIS A CD2   1 
ATOM   4785 C CE1   . HIS A 1 674 ? 144.768 150.881 110.387 1.00 92.53  ? 674 HIS A CE1   1 
ATOM   4786 N NE2   . HIS A 1 674 ? 145.231 149.838 109.722 1.00 89.40  ? 674 HIS A NE2   1 
ATOM   4787 N N     . TRP A 1 675 ? 143.612 154.558 107.316 1.00 79.50  ? 675 TRP A N     1 
ATOM   4788 C CA    . TRP A 1 675 ? 142.289 154.967 107.778 1.00 90.11  ? 675 TRP A CA    1 
ATOM   4789 C C     . TRP A 1 675 ? 141.226 154.634 106.739 1.00 91.68  ? 675 TRP A C     1 
ATOM   4790 O O     . TRP A 1 675 ? 140.174 154.071 107.065 1.00 97.19  ? 675 TRP A O     1 
ATOM   4791 C CB    . TRP A 1 675 ? 142.285 156.465 108.093 1.00 95.56  ? 675 TRP A CB    1 
ATOM   4792 C CG    . TRP A 1 675 ? 140.989 156.973 108.656 1.00 89.92  ? 675 TRP A CG    1 
ATOM   4793 C CD1   . TRP A 1 675 ? 140.676 157.130 109.972 1.00 91.29  ? 675 TRP A CD1   1 
ATOM   4794 C CD2   . TRP A 1 675 ? 139.838 157.400 107.918 1.00 89.87  ? 675 TRP A CD2   1 
ATOM   4795 N NE1   . TRP A 1 675 ? 139.405 157.623 110.102 1.00 91.54  ? 675 TRP A NE1   1 
ATOM   4796 C CE2   . TRP A 1 675 ? 138.868 157.798 108.855 1.00 89.73  ? 675 TRP A CE2   1 
ATOM   4797 C CE3   . TRP A 1 675 ? 139.534 157.481 106.556 1.00 100.26 ? 675 TRP A CE3   1 
ATOM   4798 C CZ2   . TRP A 1 675 ? 137.614 158.267 108.477 1.00 101.41 ? 675 TRP A CZ2   1 
ATOM   4799 C CZ3   . TRP A 1 675 ? 138.287 157.949 106.183 1.00 104.11 ? 675 TRP A CZ3   1 
ATOM   4800 C CH2   . TRP A 1 675 ? 137.343 158.335 107.140 1.00 104.62 ? 675 TRP A CH2   1 
ATOM   4801 N N     . GLN A 1 676 ? 141.491 154.971 105.475 1.00 82.75  ? 676 GLN A N     1 
ATOM   4802 C CA    . GLN A 1 676 ? 140.559 154.640 104.402 1.00 75.88  ? 676 GLN A CA    1 
ATOM   4803 C C     . GLN A 1 676 ? 140.406 153.133 104.252 1.00 81.89  ? 676 GLN A C     1 
ATOM   4804 O O     . GLN A 1 676 ? 139.299 152.634 104.020 1.00 89.26  ? 676 GLN A O     1 
ATOM   4805 C CB    . GLN A 1 676 ? 141.026 155.262 103.087 1.00 82.35  ? 676 GLN A CB    1 
ATOM   4806 C CG    . GLN A 1 676 ? 140.764 156.756 102.959 1.00 89.02  ? 676 GLN A CG    1 
ATOM   4807 C CD    . GLN A 1 676 ? 139.336 157.074 102.553 1.00 84.58  ? 676 GLN A CD    1 
ATOM   4808 O OE1   . GLN A 1 676 ? 138.428 156.265 102.737 1.00 82.89  ? 676 GLN A OE1   1 
ATOM   4809 N NE2   . GLN A 1 676 ? 139.134 158.258 101.989 1.00 86.63  ? 676 GLN A NE2   1 
ATOM   4810 N N     . LEU A 1 677 ? 141.510 152.392 104.372 1.00 77.42  ? 677 LEU A N     1 
ATOM   4811 C CA    . LEU A 1 677 ? 141.447 150.941 104.237 1.00 73.18  ? 677 LEU A CA    1 
ATOM   4812 C C     . LEU A 1 677 ? 140.592 150.314 105.333 1.00 79.59  ? 677 LEU A C     1 
ATOM   4813 O O     . LEU A 1 677 ? 139.682 149.525 105.052 1.00 89.01  ? 677 LEU A O     1 
ATOM   4814 C CB    . LEU A 1 677 ? 142.855 150.353 104.260 1.00 73.00  ? 677 LEU A CB    1 
ATOM   4815 C CG    . LEU A 1 677 ? 142.934 148.830 104.341 1.00 76.10  ? 677 LEU A CG    1 
ATOM   4816 C CD1   . LEU A 1 677 ? 142.309 148.194 103.111 1.00 80.87  ? 677 LEU A CD1   1 
ATOM   4817 C CD2   . LEU A 1 677 ? 144.372 148.374 104.512 1.00 83.53  ? 677 LEU A CD2   1 
ATOM   4818 N N     . ARG A 1 678 ? 140.870 150.652 106.592 1.00 78.77  ? 678 ARG A N     1 
ATOM   4819 C CA    . ARG A 1 678 ? 140.194 150.005 107.712 1.00 89.44  ? 678 ARG A CA    1 
ATOM   4820 C C     . ARG A 1 678 ? 138.758 150.488 107.881 1.00 92.32  ? 678 ARG A C     1 
ATOM   4821 O O     . ARG A 1 678 ? 137.843 149.678 108.067 1.00 96.34  ? 678 ARG A O     1 
ATOM   4822 C CB    . ARG A 1 678 ? 140.980 150.236 109.003 1.00 94.78  ? 678 ARG A CB    1 
ATOM   4823 C CG    . ARG A 1 678 ? 142.045 149.194 109.287 1.00 99.34  ? 678 ARG A CG    1 
ATOM   4824 C CD    . ARG A 1 678 ? 141.438 147.824 109.532 1.00 106.02 ? 678 ARG A CD    1 
ATOM   4825 N NE    . ARG A 1 678 ? 141.450 146.998 108.331 1.00 108.32 ? 678 ARG A NE    1 
ATOM   4826 C CZ    . ARG A 1 678 ? 142.449 146.198 107.985 1.00 110.14 ? 678 ARG A CZ    1 
ATOM   4827 N NH1   . ARG A 1 678 ? 143.537 146.089 108.730 1.00 110.70 ? 678 ARG A NH1   1 
ATOM   4828 N NH2   . ARG A 1 678 ? 142.355 145.489 106.863 1.00 106.74 ? 678 ARG A NH2   1 
ATOM   4829 N N     . PHE A 1 679 ? 138.535 151.800 107.821 1.00 81.68  ? 679 PHE A N     1 
ATOM   4830 C CA    . PHE A 1 679 ? 137.249 152.363 108.200 1.00 79.57  ? 679 PHE A CA    1 
ATOM   4831 C C     . PHE A 1 679 ? 136.313 152.623 107.027 1.00 90.18  ? 679 PHE A C     1 
ATOM   4832 O O     . PHE A 1 679 ? 135.139 152.929 107.259 1.00 100.19 ? 679 PHE A O     1 
ATOM   4833 C CB    . PHE A 1 679 ? 137.456 153.663 108.980 1.00 90.70  ? 679 PHE A CB    1 
ATOM   4834 C CG    . PHE A 1 679 ? 137.994 153.455 110.364 1.00 99.64  ? 679 PHE A CG    1 
ATOM   4835 C CD1   . PHE A 1 679 ? 137.144 153.135 111.409 1.00 108.04 ? 679 PHE A CD1   1 
ATOM   4836 C CD2   . PHE A 1 679 ? 139.347 153.578 110.623 1.00 101.64 ? 679 PHE A CD2   1 
ATOM   4837 C CE1   . PHE A 1 679 ? 137.634 152.941 112.684 1.00 118.53 ? 679 PHE A CE1   1 
ATOM   4838 C CE2   . PHE A 1 679 ? 139.843 153.386 111.896 1.00 108.33 ? 679 PHE A CE2   1 
ATOM   4839 C CZ    . PHE A 1 679 ? 138.985 153.067 112.928 1.00 117.10 ? 679 PHE A CZ    1 
ATOM   4840 N N     . HIS A 1 680 ? 136.787 152.530 105.786 1.00 86.69  ? 680 HIS A N     1 
ATOM   4841 C CA    . HIS A 1 680 ? 135.903 152.701 104.640 1.00 86.18  ? 680 HIS A CA    1 
ATOM   4842 C C     . HIS A 1 680 ? 135.845 151.475 103.746 1.00 81.17  ? 680 HIS A C     1 
ATOM   4843 O O     . HIS A 1 680 ? 134.750 150.989 103.439 1.00 89.79  ? 680 HIS A O     1 
ATOM   4844 C CB    . HIS A 1 680 ? 136.321 153.922 103.809 1.00 91.53  ? 680 HIS A CB    1 
ATOM   4845 C CG    . HIS A 1 680 ? 135.407 154.199 102.657 1.00 91.96  ? 680 HIS A CG    1 
ATOM   4846 N ND1   . HIS A 1 680 ? 134.263 154.958 102.780 1.00 94.85  ? 680 HIS A ND1   1 
ATOM   4847 C CD2   . HIS A 1 680 ? 135.458 153.803 101.364 1.00 90.23  ? 680 HIS A CD2   1 
ATOM   4848 C CE1   . HIS A 1 680 ? 133.655 155.027 101.610 1.00 96.10  ? 680 HIS A CE1   1 
ATOM   4849 N NE2   . HIS A 1 680 ? 134.359 154.334 100.733 1.00 94.26  ? 680 HIS A NE2   1 
ATOM   4850 N N     . TYR A 1 681 ? 136.994 150.964 103.307 1.00 75.43  ? 681 TYR A N     1 
ATOM   4851 C CA    . TYR A 1 681 ? 136.998 149.841 102.377 1.00 75.48  ? 681 TYR A CA    1 
ATOM   4852 C C     . TYR A 1 681 ? 136.499 148.567 103.046 1.00 87.02  ? 681 TYR A C     1 
ATOM   4853 O O     . TYR A 1 681 ? 135.677 147.837 102.478 1.00 96.58  ? 681 TYR A O     1 
ATOM   4854 C CB    . TYR A 1 681 ? 138.404 149.644 101.815 1.00 78.73  ? 681 TYR A CB    1 
ATOM   4855 C CG    . TYR A 1 681 ? 138.528 148.499 100.843 1.00 82.86  ? 681 TYR A CG    1 
ATOM   4856 C CD1   . TYR A 1 681 ? 138.141 148.642 99.520  1.00 86.30  ? 681 TYR A CD1   1 
ATOM   4857 C CD2   . TYR A 1 681 ? 139.049 147.277 101.246 1.00 88.72  ? 681 TYR A CD2   1 
ATOM   4858 C CE1   . TYR A 1 681 ? 138.257 147.597 98.626  1.00 93.75  ? 681 TYR A CE1   1 
ATOM   4859 C CE2   . TYR A 1 681 ? 139.171 146.226 100.359 1.00 92.42  ? 681 TYR A CE2   1 
ATOM   4860 C CZ    . TYR A 1 681 ? 138.774 146.391 99.051  1.00 97.80  ? 681 TYR A CZ    1 
ATOM   4861 O OH    . TYR A 1 681 ? 138.893 145.346 98.165  1.00 99.99  ? 681 TYR A OH    1 
ATOM   4862 N N     . GLY A 1 682 ? 136.985 148.282 104.256 1.00 84.22  ? 682 GLY A N     1 
ATOM   4863 C CA    . GLY A 1 682 ? 136.588 147.056 104.930 1.00 88.47  ? 682 GLY A CA    1 
ATOM   4864 C C     . GLY A 1 682 ? 135.107 147.015 105.246 1.00 91.65  ? 682 GLY A C     1 
ATOM   4865 O O     . GLY A 1 682 ? 134.447 145.989 105.058 1.00 91.02  ? 682 GLY A O     1 
ATOM   4866 N N     . ILE A 1 683 ? 134.560 148.132 105.727 1.00 93.78  ? 683 ILE A N     1 
ATOM   4867 C CA    . ILE A 1 683 ? 133.137 148.172 106.037 1.00 94.41  ? 683 ILE A CA    1 
ATOM   4868 C C     . ILE A 1 683 ? 132.305 148.152 104.760 1.00 94.38  ? 683 ILE A C     1 
ATOM   4869 O O     . ILE A 1 683 ? 131.191 147.620 104.750 1.00 101.67 ? 683 ILE A O     1 
ATOM   4870 C CB    . ILE A 1 683 ? 132.818 149.390 106.920 1.00 93.25  ? 683 ILE A CB    1 
ATOM   4871 C CG1   . ILE A 1 683 ? 131.351 149.377 107.344 1.00 101.94 ? 683 ILE A CG1   1 
ATOM   4872 C CG2   . ILE A 1 683 ? 133.167 150.674 106.203 1.00 96.32  ? 683 ILE A CG2   1 
ATOM   4873 C CD1   . ILE A 1 683 ? 131.039 150.360 108.434 1.00 108.72 ? 683 ILE A CD1   1 
ATOM   4874 N N     . THR A 1 684 ? 132.822 148.713 103.664 1.00 92.73  ? 684 THR A N     1 
ATOM   4875 C CA    . THR A 1 684 ? 132.140 148.570 102.381 1.00 94.74  ? 684 THR A CA    1 
ATOM   4876 C C     . THR A 1 684 ? 132.080 147.108 101.956 1.00 98.09  ? 684 THR A C     1 
ATOM   4877 O O     . THR A 1 684 ? 131.043 146.635 101.473 1.00 105.52 ? 684 THR A O     1 
ATOM   4878 C CB    . THR A 1 684 ? 132.838 149.413 101.312 1.00 98.08  ? 684 THR A CB    1 
ATOM   4879 O OG1   . THR A 1 684 ? 132.649 150.804 101.600 1.00 99.08  ? 684 THR A OG1   1 
ATOM   4880 C CG2   . THR A 1 684 ? 132.274 149.109 99.931  1.00 94.40  ? 684 THR A CG2   1 
ATOM   4881 N N     . GLN A 1 685 ? 133.180 146.373 102.136 1.00 93.74  ? 685 GLN A N     1 
ATOM   4882 C CA    . GLN A 1 685 ? 133.174 144.946 101.829 1.00 96.70  ? 685 GLN A CA    1 
ATOM   4883 C C     . GLN A 1 685 ? 132.189 144.197 102.718 1.00 98.55  ? 685 GLN A C     1 
ATOM   4884 O O     . GLN A 1 685 ? 131.469 143.307 102.250 1.00 102.98 ? 685 GLN A O     1 
ATOM   4885 C CB    . GLN A 1 685 ? 134.580 144.368 101.983 1.00 97.22  ? 685 GLN A CB    1 
ATOM   4886 C CG    . GLN A 1 685 ? 135.622 145.013 101.088 1.00 101.93 ? 685 GLN A CG    1 
ATOM   4887 C CD    . GLN A 1 685 ? 135.352 144.783 99.616  1.00 108.98 ? 685 GLN A CD    1 
ATOM   4888 O OE1   . GLN A 1 685 ? 135.002 143.679 99.204  1.00 111.74 ? 685 GLN A OE1   1 
ATOM   4889 N NE2   . GLN A 1 685 ? 135.511 145.830 98.815  1.00 108.82 ? 685 GLN A NE2   1 
ATOM   4890 N N     . LEU A 1 686 ? 132.145 144.546 104.004 1.00 97.73  ? 686 LEU A N     1 
ATOM   4891 C CA    . LEU A 1 686 ? 131.201 143.908 104.917 1.00 98.51  ? 686 LEU A CA    1 
ATOM   4892 C C     . LEU A 1 686 ? 129.759 144.192 104.513 1.00 104.52 ? 686 LEU A C     1 
ATOM   4893 O O     . LEU A 1 686 ? 128.903 143.301 104.572 1.00 106.13 ? 686 LEU A O     1 
ATOM   4894 C CB    . LEU A 1 686 ? 131.458 144.379 106.348 1.00 98.94  ? 686 LEU A CB    1 
ATOM   4895 C CG    . LEU A 1 686 ? 130.466 143.905 107.411 1.00 99.53  ? 686 LEU A CG    1 
ATOM   4896 C CD1   . LEU A 1 686 ? 130.523 142.396 107.564 1.00 102.33 ? 686 LEU A CD1   1 
ATOM   4897 C CD2   . LEU A 1 686 ? 130.733 144.595 108.739 1.00 102.87 ? 686 LEU A CD2   1 
ATOM   4898 N N     . LEU A 1 687 ? 129.470 145.430 104.106 1.00 105.82 ? 687 LEU A N     1 
ATOM   4899 C CA    . LEU A 1 687 ? 128.113 145.788 103.707 1.00 98.77  ? 687 LEU A CA    1 
ATOM   4900 C C     . LEU A 1 687 ? 127.715 145.106 102.405 1.00 96.28  ? 687 LEU A C     1 
ATOM   4901 O O     . LEU A 1 687 ? 126.561 144.696 102.243 1.00 99.86  ? 687 LEU A O     1 
ATOM   4902 C CB    . LEU A 1 687 ? 127.987 147.305 103.576 1.00 97.28  ? 687 LEU A CB    1 
ATOM   4903 C CG    . LEU A 1 687 ? 127.937 148.111 104.876 1.00 102.33 ? 687 LEU A CG    1 
ATOM   4904 C CD1   . LEU A 1 687 ? 128.012 149.600 104.580 1.00 110.78 ? 687 LEU A CD1   1 
ATOM   4905 C CD2   . LEU A 1 687 ? 126.677 147.787 105.662 1.00 96.77  ? 687 LEU A CD2   1 
ATOM   4906 N N     . ARG A 1 688 ? 128.648 144.980 101.459 1.00 99.39  ? 688 ARG A N     1 
ATOM   4907 C CA    . ARG A 1 688 ? 128.305 144.328 100.200 1.00 107.22 ? 688 ARG A CA    1 
ATOM   4908 C C     . ARG A 1 688 ? 128.189 142.817 100.366 1.00 109.00 ? 688 ARG A C     1 
ATOM   4909 O O     . ARG A 1 688 ? 127.415 142.176 99.646  1.00 111.62 ? 688 ARG A O     1 
ATOM   4910 C CB    . ARG A 1 688 ? 129.327 144.679 99.117  1.00 110.72 ? 688 ARG A CB    1 
ATOM   4911 C CG    . ARG A 1 688 ? 130.612 143.871 99.155  1.00 112.13 ? 688 ARG A CG    1 
ATOM   4912 C CD    . ARG A 1 688 ? 131.439 144.112 97.904  1.00 115.16 ? 688 ARG A CD    1 
ATOM   4913 N NE    . ARG A 1 688 ? 132.556 143.181 97.800  1.00 121.48 ? 688 ARG A NE    1 
ATOM   4914 C CZ    . ARG A 1 688 ? 132.488 141.992 97.216  1.00 120.39 ? 688 ARG A CZ    1 
ATOM   4915 N NH1   . ARG A 1 688 ? 131.365 141.553 96.671  1.00 113.91 ? 688 ARG A NH1   1 
ATOM   4916 N NH2   . ARG A 1 688 ? 133.574 141.225 97.179  1.00 118.93 ? 688 ARG A NH2   1 
ATOM   4917 N N     . THR A 1 689 ? 128.941 142.231 101.302 1.00 110.76 ? 689 THR A N     1 
ATOM   4918 C CA    . THR A 1 689 ? 128.789 140.806 101.578 1.00 111.24 ? 689 THR A CA    1 
ATOM   4919 C C     . THR A 1 689 ? 127.511 140.534 102.361 1.00 112.05 ? 689 THR A C     1 
ATOM   4920 O O     . THR A 1 689 ? 126.796 139.564 102.079 1.00 112.05 ? 689 THR A O     1 
ATOM   4921 C CB    . THR A 1 689 ? 130.008 140.282 102.336 1.00 105.83 ? 689 THR A CB    1 
ATOM   4922 O OG1   . THR A 1 689 ? 131.189 140.504 101.556 1.00 110.69 ? 689 THR A OG1   1 
ATOM   4923 C CG2   . THR A 1 689 ? 129.865 138.796 102.610 1.00 98.19  ? 689 THR A CG2   1 
ATOM   4924 N N     . TYR A 1 690 ? 127.202 141.384 103.342 1.00 110.46 ? 690 TYR A N     1 
ATOM   4925 C CA    . TYR A 1 690 ? 125.976 141.294 104.133 1.00 105.32 ? 690 TYR A CA    1 
ATOM   4926 C C     . TYR A 1 690 ? 125.167 142.555 103.863 1.00 105.44 ? 690 TYR A C     1 
ATOM   4927 O O     . TYR A 1 690 ? 125.350 143.577 104.543 1.00 103.10 ? 690 TYR A O     1 
ATOM   4928 C CB    . TYR A 1 690 ? 126.273 141.155 105.626 1.00 103.97 ? 690 TYR A CB    1 
ATOM   4929 C CG    . TYR A 1 690 ? 127.002 139.892 106.023 1.00 99.83  ? 690 TYR A CG    1 
ATOM   4930 C CD1   . TYR A 1 690 ? 127.112 138.821 105.150 1.00 98.82  ? 690 TYR A CD1   1 
ATOM   4931 C CD2   . TYR A 1 690 ? 127.572 139.771 107.284 1.00 95.16  ? 690 TYR A CD2   1 
ATOM   4932 C CE1   . TYR A 1 690 ? 127.777 137.671 105.517 1.00 99.95  ? 690 TYR A CE1   1 
ATOM   4933 C CE2   . TYR A 1 690 ? 128.235 138.628 107.658 1.00 91.89  ? 690 TYR A CE2   1 
ATOM   4934 C CZ    . TYR A 1 690 ? 128.336 137.580 106.772 1.00 97.72  ? 690 TYR A CZ    1 
ATOM   4935 O OH    . TYR A 1 690 ? 128.999 136.434 107.144 1.00 104.54 ? 690 TYR A OH    1 
ATOM   4936 N N     . PRO A 1 691 ? 124.268 142.531 102.885 1.00 106.80 ? 691 PRO A N     1 
ATOM   4937 C CA    . PRO A 1 691 ? 123.454 143.714 102.589 1.00 106.43 ? 691 PRO A CA    1 
ATOM   4938 C C     . PRO A 1 691 ? 122.531 144.040 103.748 1.00 108.57 ? 691 PRO A C     1 
ATOM   4939 O O     . PRO A 1 691 ? 122.303 143.195 104.626 1.00 114.02 ? 691 PRO A O     1 
ATOM   4940 C CB    . PRO A 1 691 ? 122.659 143.293 101.342 1.00 104.80 ? 691 PRO A CB    1 
ATOM   4941 C CG    . PRO A 1 691 ? 123.439 142.161 100.753 1.00 100.48 ? 691 PRO A CG    1 
ATOM   4942 C CD    . PRO A 1 691 ? 124.038 141.445 101.919 1.00 103.92 ? 691 PRO A CD    1 
ATOM   4943 N N     . PRO A 1 692 ? 121.995 145.262 103.800 1.00 103.00 ? 692 PRO A N     1 
ATOM   4944 C CA    . PRO A 1 692 ? 121.051 145.594 104.879 1.00 108.36 ? 692 PRO A CA    1 
ATOM   4945 C C     . PRO A 1 692 ? 119.827 144.696 104.905 1.00 118.43 ? 692 PRO A C     1 
ATOM   4946 O O     . PRO A 1 692 ? 119.231 144.506 105.972 1.00 121.42 ? 692 PRO A O     1 
ATOM   4947 C CB    . PRO A 1 692 ? 120.679 147.052 104.579 1.00 107.98 ? 692 PRO A CB    1 
ATOM   4948 C CG    . PRO A 1 692 ? 121.837 147.581 103.801 1.00 102.22 ? 692 PRO A CG    1 
ATOM   4949 C CD    . PRO A 1 692 ? 122.318 146.433 102.968 1.00 102.00 ? 692 PRO A CD    1 
ATOM   4950 N N     . ASP A 1 693 ? 119.432 144.137 103.760 1.00 122.44 ? 693 ASP A N     1 
ATOM   4951 C CA    . ASP A 1 693 ? 118.325 143.192 103.680 1.00 126.41 ? 693 ASP A CA    1 
ATOM   4952 C C     . ASP A 1 693 ? 118.805 141.752 103.521 1.00 128.00 ? 693 ASP A C     1 
ATOM   4953 O O     . ASP A 1 693 ? 118.145 140.946 102.855 1.00 128.37 ? 693 ASP A O     1 
ATOM   4954 C CB    . ASP A 1 693 ? 117.378 143.572 102.538 1.00 129.15 ? 693 ASP A CB    1 
ATOM   4955 C CG    . ASP A 1 693 ? 118.059 143.577 101.175 1.00 127.63 ? 693 ASP A CG    1 
ATOM   4956 O OD1   . ASP A 1 693 ? 119.288 143.367 101.100 1.00 122.59 ? 693 ASP A OD1   1 
ATOM   4957 O OD2   . ASP A 1 693 ? 117.353 143.793 100.168 1.00 129.66 ? 693 ASP A OD2   1 
ATOM   4958 N N     . LYS A 1 694 ? 119.946 141.417 104.118 1.00 128.01 ? 694 LYS A N     1 
ATOM   4959 C CA    . LYS A 1 694 ? 120.483 140.066 104.024 1.00 128.46 ? 694 LYS A CA    1 
ATOM   4960 C C     . LYS A 1 694 ? 119.569 139.073 104.731 1.00 135.13 ? 694 LYS A C     1 
ATOM   4961 O O     . LYS A 1 694 ? 119.040 139.349 105.811 1.00 135.02 ? 694 LYS A O     1 
ATOM   4962 C CB    . LYS A 1 694 ? 121.885 140.013 104.633 1.00 124.30 ? 694 LYS A CB    1 
ATOM   4963 C CG    . LYS A 1 694 ? 122.540 138.642 104.600 1.00 121.54 ? 694 LYS A CG    1 
ATOM   4964 C CD    . LYS A 1 694 ? 122.787 138.179 103.174 1.00 121.55 ? 694 LYS A CD    1 
ATOM   4965 C CE    . LYS A 1 694 ? 123.532 136.854 103.147 1.00 120.07 ? 694 LYS A CE    1 
ATOM   4966 N NZ    . LYS A 1 694 ? 123.832 136.413 101.757 1.00 115.97 ? 694 LYS A NZ    1 
ATOM   4967 N N     . VAL A 1 695 ? 119.381 137.912 104.111 1.00 138.45 ? 695 VAL A N     1 
ATOM   4968 C CA    . VAL A 1 695 ? 118.563 136.857 104.697 1.00 139.04 ? 695 VAL A CA    1 
ATOM   4969 C C     . VAL A 1 695 ? 119.373 135.572 104.818 1.00 135.36 ? 695 VAL A C     1 
ATOM   4970 O O     . VAL A 1 695 ? 120.385 135.399 104.139 1.00 134.32 ? 695 VAL A O     1 
ATOM   4971 C CB    . VAL A 1 695 ? 117.284 136.618 103.875 1.00 135.44 ? 695 VAL A CB    1 
ATOM   4972 C CG1   . VAL A 1 695 ? 116.483 135.469 104.469 1.00 129.77 ? 695 VAL A CG1   1 
ATOM   4973 C CG2   . VAL A 1 695 ? 116.444 137.884 103.816 1.00 133.18 ? 695 VAL A CG2   1 
ATOM   4974 N N     . PRO A 1 701 ? 115.767 141.101 108.780 1.00 134.43 ? 701 PRO A N     1 
ATOM   4975 C CA    . PRO A 1 701 ? 117.021 140.848 108.062 1.00 133.54 ? 701 PRO A CA    1 
ATOM   4976 C C     . PRO A 1 701 ? 118.174 140.504 109.000 1.00 134.47 ? 701 PRO A C     1 
ATOM   4977 O O     . PRO A 1 701 ? 117.957 140.319 110.198 1.00 137.51 ? 701 PRO A O     1 
ATOM   4978 C CB    . PRO A 1 701 ? 117.281 142.171 107.340 1.00 132.96 ? 701 PRO A CB    1 
ATOM   4979 C CG    . PRO A 1 701 ? 115.925 142.752 107.140 1.00 133.52 ? 701 PRO A CG    1 
ATOM   4980 C CD    . PRO A 1 701 ? 115.135 142.363 108.359 1.00 133.47 ? 701 PRO A CD    1 
ATOM   4981 N N     . PHE A 1 702 ? 119.387 140.413 108.451 1.00 131.23 ? 702 PHE A N     1 
ATOM   4982 C CA    . PHE A 1 702 ? 120.548 140.090 109.274 1.00 132.56 ? 702 PHE A CA    1 
ATOM   4983 C C     . PHE A 1 702 ? 120.834 141.192 110.286 1.00 135.55 ? 702 PHE A C     1 
ATOM   4984 O O     . PHE A 1 702 ? 121.149 140.908 111.448 1.00 136.22 ? 702 PHE A O     1 
ATOM   4985 C CB    . PHE A 1 702 ? 121.768 139.841 108.387 1.00 126.22 ? 702 PHE A CB    1 
ATOM   4986 C CG    . PHE A 1 702 ? 122.972 139.349 109.140 1.00 127.56 ? 702 PHE A CG    1 
ATOM   4987 C CD1   . PHE A 1 702 ? 123.139 138.000 109.398 1.00 127.79 ? 702 PHE A CD1   1 
ATOM   4988 C CD2   . PHE A 1 702 ? 123.936 140.236 109.592 1.00 126.54 ? 702 PHE A CD2   1 
ATOM   4989 C CE1   . PHE A 1 702 ? 124.245 137.543 110.091 1.00 128.61 ? 702 PHE A CE1   1 
ATOM   4990 C CE2   . PHE A 1 702 ? 125.042 139.787 110.285 1.00 126.98 ? 702 PHE A CE2   1 
ATOM   4991 C CZ    . PHE A 1 702 ? 125.197 138.439 110.535 1.00 129.08 ? 702 PHE A CZ    1 
ATOM   4992 N N     . TRP A 1 703 ? 120.731 142.453 109.867 1.00 134.79 ? 703 TRP A N     1 
ATOM   4993 C CA    . TRP A 1 703 ? 120.970 143.588 110.759 1.00 136.26 ? 703 TRP A CA    1 
ATOM   4994 C C     . TRP A 1 703 ? 119.670 143.947 111.482 1.00 140.31 ? 703 TRP A C     1 
ATOM   4995 O O     . TRP A 1 703 ? 119.009 144.948 111.202 1.00 141.52 ? 703 TRP A O     1 
ATOM   4996 C CB    . TRP A 1 703 ? 121.527 144.772 109.979 1.00 130.43 ? 703 TRP A CB    1 
ATOM   4997 C CG    . TRP A 1 703 ? 122.790 144.467 109.232 1.00 121.09 ? 703 TRP A CG    1 
ATOM   4998 C CD1   . TRP A 1 703 ? 122.925 144.292 107.885 1.00 116.56 ? 703 TRP A CD1   1 
ATOM   4999 C CD2   . TRP A 1 703 ? 124.097 144.300 109.790 1.00 117.03 ? 703 TRP A CD2   1 
ATOM   5000 N NE1   . TRP A 1 703 ? 124.235 144.029 107.571 1.00 107.97 ? 703 TRP A NE1   1 
ATOM   5001 C CE2   . TRP A 1 703 ? 124.975 144.027 108.724 1.00 112.96 ? 703 TRP A CE2   1 
ATOM   5002 C CE3   . TRP A 1 703 ? 124.611 144.354 111.089 1.00 123.54 ? 703 TRP A CE3   1 
ATOM   5003 C CZ2   . TRP A 1 703 ? 126.336 143.810 108.916 1.00 116.42 ? 703 TRP A CZ2   1 
ATOM   5004 C CZ3   . TRP A 1 703 ? 125.963 144.139 111.277 1.00 124.68 ? 703 TRP A CZ3   1 
ATOM   5005 C CH2   . TRP A 1 703 ? 126.810 143.870 110.197 1.00 121.22 ? 703 TRP A CH2   1 
ATOM   5006 N N     . SER A 1 704 ? 119.311 143.091 112.435 1.00 142.57 ? 704 SER A N     1 
ATOM   5007 C CA    . SER A 1 704 ? 118.099 143.254 113.223 1.00 143.97 ? 704 SER A CA    1 
ATOM   5008 C C     . SER A 1 704 ? 118.415 143.018 114.693 1.00 146.41 ? 704 SER A C     1 
ATOM   5009 O O     . SER A 1 704 ? 119.477 142.499 115.050 1.00 147.02 ? 704 SER A O     1 
ATOM   5010 C CB    . SER A 1 704 ? 116.993 142.298 112.754 1.00 143.03 ? 704 SER A CB    1 
ATOM   5011 O OG    . SER A 1 704 ? 117.375 140.946 112.939 1.00 142.94 ? 704 SER A OG    1 
ATOM   5012 N N     . GLY A 1 705 ? 117.472 143.403 115.549 1.00 148.16 ? 705 GLY A N     1 
ATOM   5013 C CA    . GLY A 1 705 ? 117.634 143.273 116.977 1.00 150.04 ? 705 GLY A CA    1 
ATOM   5014 C C     . GLY A 1 705 ? 118.810 144.075 117.493 1.00 153.07 ? 705 GLY A C     1 
ATOM   5015 O O     . GLY A 1 705 ? 118.972 145.258 117.176 1.00 152.36 ? 705 GLY A O     1 
ATOM   5016 N N     . PRO A 1 706 ? 119.652 143.444 118.316 1.00 155.06 ? 706 PRO A N     1 
ATOM   5017 C CA    . PRO A 1 706 ? 120.859 144.139 118.795 1.00 153.34 ? 706 PRO A CA    1 
ATOM   5018 C C     . PRO A 1 706 ? 121.775 144.593 117.673 1.00 151.29 ? 706 PRO A C     1 
ATOM   5019 O O     . PRO A 1 706 ? 122.398 145.656 117.785 1.00 148.30 ? 706 PRO A O     1 
ATOM   5020 C CB    . PRO A 1 706 ? 121.535 143.089 119.688 1.00 148.49 ? 706 PRO A CB    1 
ATOM   5021 C CG    . PRO A 1 706 ? 120.434 142.158 120.085 1.00 146.52 ? 706 PRO A CG    1 
ATOM   5022 C CD    . PRO A 1 706 ? 119.511 142.103 118.906 1.00 152.42 ? 706 PRO A CD    1 
ATOM   5023 N N     . LYS A 1 707 ? 121.875 143.821 116.594 1.00 151.74 ? 707 LYS A N     1 
ATOM   5024 C CA    . LYS A 1 707 ? 122.714 144.197 115.466 1.00 149.47 ? 707 LYS A CA    1 
ATOM   5025 C C     . LYS A 1 707 ? 122.003 145.219 114.588 1.00 147.43 ? 707 LYS A C     1 
ATOM   5026 O O     . LYS A 1 707 ? 120.803 145.105 114.322 1.00 146.69 ? 707 LYS A O     1 
ATOM   5027 C CB    . LYS A 1 707 ? 123.085 142.964 114.642 1.00 144.46 ? 707 LYS A CB    1 
ATOM   5028 C CG    . LYS A 1 707 ? 123.895 141.928 115.407 1.00 141.85 ? 707 LYS A CG    1 
ATOM   5029 C CD    . LYS A 1 707 ? 124.230 140.730 114.533 1.00 142.32 ? 707 LYS A CD    1 
ATOM   5030 C CE    . LYS A 1 707 ? 122.970 140.019 114.064 1.00 140.80 ? 707 LYS A CE    1 
ATOM   5031 N NZ    . LYS A 1 707 ? 123.283 138.839 113.211 1.00 136.93 ? 707 LYS A NZ    1 
ATOM   5032 N N     . GLN A 1 708 ? 122.754 146.223 114.142 1.00 144.81 ? 708 GLN A N     1 
ATOM   5033 C CA    . GLN A 1 708 ? 122.234 147.270 113.277 1.00 143.49 ? 708 GLN A CA    1 
ATOM   5034 C C     . GLN A 1 708 ? 123.195 147.499 112.119 1.00 137.87 ? 708 GLN A C     1 
ATOM   5035 O O     . GLN A 1 708 ? 124.398 147.249 112.231 1.00 135.94 ? 708 GLN A O     1 
ATOM   5036 C CB    . GLN A 1 708 ? 122.015 148.581 114.046 1.00 143.98 ? 708 GLN A CB    1 
ATOM   5037 C CG    . GLN A 1 708 ? 120.920 148.505 115.098 1.00 145.94 ? 708 GLN A CG    1 
ATOM   5038 C CD    . GLN A 1 708 ? 119.551 148.252 114.497 1.00 148.07 ? 708 GLN A CD    1 
ATOM   5039 O OE1   . GLN A 1 708 ? 119.258 148.690 113.385 1.00 148.47 ? 708 GLN A OE1   1 
ATOM   5040 N NE2   . GLN A 1 708 ? 118.704 147.539 115.231 1.00 148.05 ? 708 GLN A NE2   1 
ATOM   5041 N N     . CYS A 1 709 ? 122.649 147.978 111.008 1.00 133.95 ? 709 CYS A N     1 
ATOM   5042 C CA    . CYS A 1 709 ? 123.451 148.185 109.808 1.00 130.32 ? 709 CYS A CA    1 
ATOM   5043 C C     . CYS A 1 709 ? 124.486 149.280 110.046 1.00 133.25 ? 709 CYS A C     1 
ATOM   5044 O O     . CYS A 1 709 ? 124.128 150.382 110.476 1.00 134.72 ? 709 CYS A O     1 
ATOM   5045 C CB    . CYS A 1 709 ? 122.556 148.552 108.628 1.00 130.09 ? 709 CYS A CB    1 
ATOM   5046 S SG    . CYS A 1 709 ? 123.441 148.845 107.080 1.00 130.82 ? 709 CYS A SG    1 
ATOM   5047 N N     . PRO A 1 710 ? 125.761 149.022 109.783 1.00 127.57 ? 710 PRO A N     1 
ATOM   5048 C CA    . PRO A 1 710 ? 126.798 150.039 109.979 1.00 126.14 ? 710 PRO A CA    1 
ATOM   5049 C C     . PRO A 1 710 ? 126.880 150.969 108.772 1.00 125.44 ? 710 PRO A C     1 
ATOM   5050 O O     . PRO A 1 710 ? 126.202 150.784 107.763 1.00 127.39 ? 710 PRO A O     1 
ATOM   5051 C CB    . PRO A 1 710 ? 128.066 149.201 110.132 1.00 125.55 ? 710 PRO A CB    1 
ATOM   5052 C CG    . PRO A 1 710 ? 127.811 148.017 109.261 1.00 121.75 ? 710 PRO A CG    1 
ATOM   5053 C CD    . PRO A 1 710 ? 126.329 147.733 109.352 1.00 121.96 ? 710 PRO A CD    1 
ATOM   5054 N N     . GLN A 1 711 ? 127.732 151.988 108.895 1.00 122.84 ? 711 GLN A N     1 
ATOM   5055 C CA    . GLN A 1 711 ? 127.942 152.960 107.833 1.00 119.34 ? 711 GLN A CA    1 
ATOM   5056 C C     . GLN A 1 711 ? 129.425 153.277 107.696 1.00 112.19 ? 711 GLN A C     1 
ATOM   5057 O O     . GLN A 1 711 ? 130.121 153.446 108.709 1.00 115.71 ? 711 GLN A O     1 
ATOM   5058 C CB    . GLN A 1 711 ? 127.162 154.257 108.094 1.00 120.85 ? 711 GLN A CB    1 
ATOM   5059 C CG    . GLN A 1 711 ? 125.649 154.104 108.031 1.00 124.86 ? 711 GLN A CG    1 
ATOM   5060 C CD    . GLN A 1 711 ? 125.151 153.775 106.636 1.00 124.62 ? 711 GLN A CD    1 
ATOM   5061 O OE1   . GLN A 1 711 ? 125.814 154.068 105.641 1.00 121.05 ? 711 GLN A OE1   1 
ATOM   5062 N NE2   . GLN A 1 711 ? 123.975 153.162 106.557 1.00 126.47 ? 711 GLN A NE2   1 
ATOM   5063 N N     . PRO A 1 712 ? 129.933 153.362 106.469 1.00 105.54 ? 712 PRO A N     1 
ATOM   5064 C CA    . PRO A 1 712 ? 131.336 153.740 106.276 1.00 105.00 ? 712 PRO A CA    1 
ATOM   5065 C C     . PRO A 1 712 ? 131.596 155.179 106.692 1.00 108.44 ? 712 PRO A C     1 
ATOM   5066 O O     . PRO A 1 712 ? 130.699 156.025 106.691 1.00 114.30 ? 712 PRO A O     1 
ATOM   5067 C CB    . PRO A 1 712 ? 131.551 153.551 104.770 1.00 106.27 ? 712 PRO A CB    1 
ATOM   5068 C CG    . PRO A 1 712 ? 130.185 153.638 104.177 1.00 106.99 ? 712 PRO A CG    1 
ATOM   5069 C CD    . PRO A 1 712 ? 129.259 153.055 105.197 1.00 105.31 ? 712 PRO A CD    1 
ATOM   5070 N N     . LEU A 1 713 ? 132.847 155.448 107.051 1.00 105.05 ? 713 LEU A N     1 
ATOM   5071 C CA    . LEU A 1 713 ? 133.261 156.759 107.534 1.00 114.32 ? 713 LEU A CA    1 
ATOM   5072 C C     . LEU A 1 713 ? 133.883 157.562 106.400 1.00 117.58 ? 713 LEU A C     1 
ATOM   5073 O O     . LEU A 1 713 ? 134.721 157.046 105.653 1.00 110.92 ? 713 LEU A O     1 
ATOM   5074 C CB    . LEU A 1 713 ? 134.253 156.626 108.690 1.00 111.57 ? 713 LEU A CB    1 
ATOM   5075 C CG    . LEU A 1 713 ? 133.752 155.885 109.930 1.00 112.31 ? 713 LEU A CG    1 
ATOM   5076 C CD1   . LEU A 1 713 ? 134.796 155.921 111.034 1.00 114.28 ? 713 LEU A CD1   1 
ATOM   5077 C CD2   . LEU A 1 713 ? 132.433 156.469 110.413 1.00 111.97 ? 713 LEU A CD2   1 
ATOM   5078 N N     . LYS A 1 714 ? 133.478 158.824 106.284 1.00 122.62 ? 714 LYS A N     1 
ATOM   5079 C CA    . LYS A 1 714 ? 133.990 159.731 105.264 1.00 123.98 ? 714 LYS A CA    1 
ATOM   5080 C C     . LYS A 1 714 ? 135.012 160.669 105.894 1.00 128.73 ? 714 LYS A C     1 
ATOM   5081 O O     . LYS A 1 714 ? 134.755 161.256 106.950 1.00 131.29 ? 714 LYS A O     1 
ATOM   5082 C CB    . LYS A 1 714 ? 132.859 160.537 104.621 1.00 121.02 ? 714 LYS A CB    1 
ATOM   5083 C CG    . LYS A 1 714 ? 131.884 159.717 103.782 1.00 119.36 ? 714 LYS A CG    1 
ATOM   5084 C CD    . LYS A 1 714 ? 130.773 159.111 104.627 1.00 116.07 ? 714 LYS A CD    1 
ATOM   5085 C CE    . LYS A 1 714 ? 129.810 158.299 103.777 1.00 112.87 ? 714 LYS A CE    1 
ATOM   5086 N NZ    . LYS A 1 714 ? 128.719 157.698 104.594 1.00 109.88 ? 714 LYS A NZ    1 
ATOM   5087 N N     . PHE A 1 715 ? 136.165 160.805 105.244 1.00 130.37 ? 715 PHE A N     1 
ATOM   5088 C CA    . PHE A 1 715 ? 137.257 161.582 105.814 1.00 126.06 ? 715 PHE A CA    1 
ATOM   5089 C C     . PHE A 1 715 ? 136.964 163.076 105.748 1.00 133.22 ? 715 PHE A C     1 
ATOM   5090 O O     . PHE A 1 715 ? 136.382 163.573 104.779 1.00 136.56 ? 715 PHE A O     1 
ATOM   5091 C CB    . PHE A 1 715 ? 138.565 161.275 105.086 1.00 113.23 ? 715 PHE A CB    1 
ATOM   5092 C CG    . PHE A 1 715 ? 139.776 161.857 105.751 1.00 115.83 ? 715 PHE A CG    1 
ATOM   5093 C CD1   . PHE A 1 715 ? 140.284 161.292 106.909 1.00 116.58 ? 715 PHE A CD1   1 
ATOM   5094 C CD2   . PHE A 1 715 ? 140.414 162.963 105.216 1.00 121.18 ? 715 PHE A CD2   1 
ATOM   5095 C CE1   . PHE A 1 715 ? 141.401 161.823 107.525 1.00 120.27 ? 715 PHE A CE1   1 
ATOM   5096 C CE2   . PHE A 1 715 ? 141.533 163.497 105.827 1.00 124.53 ? 715 PHE A CE2   1 
ATOM   5097 C CZ    . PHE A 1 715 ? 142.027 162.925 106.984 1.00 123.88 ? 715 PHE A CZ    1 
ATOM   5098 N N     . ASP A 1 716 ? 137.377 163.791 106.793 1.00 134.58 ? 716 ASP A N     1 
ATOM   5099 C CA    . ASP A 1 716 ? 137.241 165.245 106.838 1.00 139.91 ? 716 ASP A CA    1 
ATOM   5100 C C     . ASP A 1 716 ? 138.305 165.767 107.793 1.00 140.62 ? 716 ASP A C     1 
ATOM   5101 O O     . ASP A 1 716 ? 138.225 165.518 109.000 1.00 141.74 ? 716 ASP A O     1 
ATOM   5102 C CB    . ASP A 1 716 ? 135.842 165.651 107.286 1.00 141.34 ? 716 ASP A CB    1 
ATOM   5103 C CG    . ASP A 1 716 ? 135.581 167.136 107.112 1.00 143.80 ? 716 ASP A CG    1 
ATOM   5104 O OD1   . ASP A 1 716 ? 136.454 167.837 106.557 1.00 143.64 ? 716 ASP A OD1   1 
ATOM   5105 O OD2   . ASP A 1 716 ? 134.500 167.602 107.528 1.00 143.63 ? 716 ASP A OD2   1 
ATOM   5106 N N     . ALA A 1 717 ? 139.294 166.483 107.253 1.00 140.30 ? 717 ALA A N     1 
ATOM   5107 C CA    . ALA A 1 717 ? 140.414 166.938 108.071 1.00 139.87 ? 717 ALA A CA    1 
ATOM   5108 C C     . ALA A 1 717 ? 139.974 167.926 109.143 1.00 143.89 ? 717 ALA A C     1 
ATOM   5109 O O     . ALA A 1 717 ? 140.614 168.023 110.196 1.00 141.87 ? 717 ALA A O     1 
ATOM   5110 C CB    . ALA A 1 717 ? 141.491 167.564 107.184 1.00 133.61 ? 717 ALA A CB    1 
ATOM   5111 N N     . SER A 1 718 ? 138.888 168.664 108.899 1.00 146.32 ? 718 SER A N     1 
ATOM   5112 C CA    . SER A 1 718 ? 138.421 169.644 109.872 1.00 145.93 ? 718 SER A CA    1 
ATOM   5113 C C     . SER A 1 718 ? 137.892 168.997 111.145 1.00 144.40 ? 718 SER A C     1 
ATOM   5114 O O     . SER A 1 718 ? 137.835 169.663 112.184 1.00 143.46 ? 718 SER A O     1 
ATOM   5115 C CB    . SER A 1 718 ? 137.337 170.526 109.250 1.00 144.76 ? 718 SER A CB    1 
ATOM   5116 O OG    . SER A 1 718 ? 136.227 169.750 108.834 1.00 143.17 ? 718 SER A OG    1 
ATOM   5117 N N     . GLN A 1 719 ? 137.507 167.725 111.092 1.00 144.95 ? 719 GLN A N     1 
ATOM   5118 C CA    . GLN A 1 719 ? 136.976 167.047 112.263 1.00 143.34 ? 719 GLN A CA    1 
ATOM   5119 C C     . GLN A 1 719 ? 138.097 166.665 113.222 1.00 142.87 ? 719 GLN A C     1 
ATOM   5120 O O     . GLN A 1 719 ? 139.236 166.413 112.817 1.00 140.46 ? 719 GLN A O     1 
ATOM   5121 C CB    . GLN A 1 719 ? 136.189 165.802 111.852 1.00 139.72 ? 719 GLN A CB    1 
ATOM   5122 C CG    . GLN A 1 719 ? 135.088 166.077 110.840 1.00 138.53 ? 719 GLN A CG    1 
ATOM   5123 C CD    . GLN A 1 719 ? 134.074 167.093 111.332 1.00 136.06 ? 719 GLN A CD    1 
ATOM   5124 O OE1   . GLN A 1 719 ? 133.761 167.153 112.521 1.00 131.07 ? 719 GLN A OE1   1 
ATOM   5125 N NE2   . GLN A 1 719 ? 133.557 167.902 110.414 1.00 138.51 ? 719 GLN A NE2   1 
ATOM   5126 N N     . ASP A 1 720 ? 137.762 166.636 114.514 1.00 145.39 ? 720 ASP A N     1 
ATOM   5127 C CA    . ASP A 1 720 ? 138.764 166.350 115.536 1.00 145.40 ? 720 ASP A CA    1 
ATOM   5128 C C     . ASP A 1 720 ? 139.208 164.891 115.502 1.00 142.44 ? 720 ASP A C     1 
ATOM   5129 O O     . ASP A 1 720 ? 140.404 164.600 115.613 1.00 140.67 ? 720 ASP A O     1 
ATOM   5130 C CB    . ASP A 1 720 ? 138.221 166.710 116.919 1.00 142.55 ? 720 ASP A CB    1 
ATOM   5131 C CG    . ASP A 1 720 ? 137.811 168.165 117.023 1.00 139.03 ? 720 ASP A CG    1 
ATOM   5132 O OD1   . ASP A 1 720 ? 138.421 169.008 116.331 1.00 139.38 ? 720 ASP A OD1   1 
ATOM   5133 O OD2   . ASP A 1 720 ? 136.879 168.467 117.798 1.00 134.72 ? 720 ASP A OD2   1 
ATOM   5134 N N     . MET A 1 721 ? 138.262 163.960 115.352 1.00 141.51 ? 721 MET A N     1 
ATOM   5135 C CA    . MET A 1 721 ? 138.583 162.542 115.500 1.00 140.18 ? 721 MET A CA    1 
ATOM   5136 C C     . MET A 1 721 ? 139.493 162.050 114.379 1.00 136.06 ? 721 MET A C     1 
ATOM   5137 O O     . MET A 1 721 ? 140.480 161.348 114.633 1.00 135.86 ? 721 MET A O     1 
ATOM   5138 C CB    . MET A 1 721 ? 137.296 161.717 115.556 1.00 142.54 ? 721 MET A CB    1 
ATOM   5139 C CG    . MET A 1 721 ? 136.398 162.055 116.739 1.00 149.07 ? 721 MET A CG    1 
ATOM   5140 S SD    . MET A 1 721 ? 135.139 163.292 116.367 1.00 158.23 ? 721 MET A SD    1 
ATOM   5141 C CE    . MET A 1 721 ? 133.914 162.285 115.529 1.00 145.14 ? 721 MET A CE    1 
ATOM   5142 N N     . HIS A 1 722 ? 139.172 162.399 113.131 1.00 130.92 ? 722 HIS A N     1 
ATOM   5143 C CA    . HIS A 1 722 ? 139.996 161.961 112.007 1.00 124.17 ? 722 HIS A CA    1 
ATOM   5144 C C     . HIS A 1 722 ? 141.394 162.559 112.089 1.00 124.60 ? 722 HIS A C     1 
ATOM   5145 O O     . HIS A 1 722 ? 142.390 161.872 111.827 1.00 122.54 ? 722 HIS A O     1 
ATOM   5146 C CB    . HIS A 1 722 ? 139.326 162.343 110.687 1.00 121.49 ? 722 HIS A CB    1 
ATOM   5147 C CG    . HIS A 1 722 ? 137.842 162.135 110.679 1.00 126.35 ? 722 HIS A CG    1 
ATOM   5148 N ND1   . HIS A 1 722 ? 137.218 161.176 111.447 1.00 123.15 ? 722 HIS A ND1   1 
ATOM   5149 C CD2   . HIS A 1 722 ? 136.857 162.771 110.000 1.00 129.67 ? 722 HIS A CD2   1 
ATOM   5150 C CE1   . HIS A 1 722 ? 135.914 161.227 111.240 1.00 123.16 ? 722 HIS A CE1   1 
ATOM   5151 N NE2   . HIS A 1 722 ? 135.669 162.187 110.366 1.00 126.50 ? 722 HIS A NE2   1 
ATOM   5152 N N     . LEU A 1 723 ? 141.485 163.838 112.458 1.00 129.36 ? 723 LEU A N     1 
ATOM   5153 C CA    . LEU A 1 723 ? 142.786 164.481 112.601 1.00 130.27 ? 723 LEU A CA    1 
ATOM   5154 C C     . LEU A 1 723 ? 143.607 163.820 113.699 1.00 129.36 ? 723 LEU A C     1 
ATOM   5155 O O     . LEU A 1 723 ? 144.806 163.578 113.524 1.00 131.83 ? 723 LEU A O     1 
ATOM   5156 C CB    . LEU A 1 723 ? 142.602 165.971 112.888 1.00 135.63 ? 723 LEU A CB    1 
ATOM   5157 C CG    . LEU A 1 723 ? 143.848 166.854 112.804 1.00 140.77 ? 723 LEU A CG    1 
ATOM   5158 C CD1   . LEU A 1 723 ? 144.374 166.898 111.378 1.00 137.41 ? 723 LEU A CD1   1 
ATOM   5159 C CD2   . LEU A 1 723 ? 143.547 168.255 113.313 1.00 140.13 ? 723 LEU A CD2   1 
ATOM   5160 N N     . LEU A 1 724 ? 142.978 163.518 114.838 1.00 128.74 ? 724 LEU A N     1 
ATOM   5161 C CA    . LEU A 1 724 ? 143.693 162.854 115.925 1.00 131.82 ? 724 LEU A CA    1 
ATOM   5162 C C     . LEU A 1 724 ? 144.168 161.468 115.510 1.00 134.14 ? 724 LEU A C     1 
ATOM   5163 O O     . LEU A 1 724 ? 145.294 161.068 115.830 1.00 135.11 ? 724 LEU A O     1 
ATOM   5164 C CB    . LEU A 1 724 ? 142.803 162.765 117.163 1.00 131.34 ? 724 LEU A CB    1 
ATOM   5165 C CG    . LEU A 1 724 ? 142.559 164.065 117.931 1.00 134.45 ? 724 LEU A CG    1 
ATOM   5166 C CD1   . LEU A 1 724 ? 141.602 163.829 119.089 1.00 134.11 ? 724 LEU A CD1   1 
ATOM   5167 C CD2   . LEU A 1 724 ? 143.872 164.651 118.427 1.00 133.12 ? 724 LEU A CD2   1 
ATOM   5168 N N     . TYR A 1 725 ? 143.319 160.719 114.803 1.00 135.10 ? 725 TYR A N     1 
ATOM   5169 C CA    . TYR A 1 725 ? 143.708 159.391 114.339 1.00 133.20 ? 725 TYR A CA    1 
ATOM   5170 C C     . TYR A 1 725 ? 144.908 159.473 113.404 1.00 129.77 ? 725 TYR A C     1 
ATOM   5171 O O     . TYR A 1 725 ? 145.880 158.722 113.555 1.00 127.29 ? 725 TYR A O     1 
ATOM   5172 C CB    . TYR A 1 725 ? 142.521 158.720 113.645 1.00 127.44 ? 725 TYR A CB    1 
ATOM   5173 C CG    . TYR A 1 725 ? 142.756 157.289 113.212 1.00 121.22 ? 725 TYR A CG    1 
ATOM   5174 C CD1   . TYR A 1 725 ? 143.317 156.999 111.975 1.00 116.89 ? 725 TYR A CD1   1 
ATOM   5175 C CD2   . TYR A 1 725 ? 142.399 156.228 114.032 1.00 124.71 ? 725 TYR A CD2   1 
ATOM   5176 C CE1   . TYR A 1 725 ? 143.526 155.696 111.572 1.00 111.41 ? 725 TYR A CE1   1 
ATOM   5177 C CE2   . TYR A 1 725 ? 142.605 154.919 113.636 1.00 120.25 ? 725 TYR A CE2   1 
ATOM   5178 C CZ    . TYR A 1 725 ? 143.169 154.661 112.405 1.00 110.55 ? 725 TYR A CZ    1 
ATOM   5179 O OH    . TYR A 1 725 ? 143.376 153.362 112.004 1.00 105.63 ? 725 TYR A OH    1 
ATOM   5180 N N     . VAL A 1 726 ? 144.860 160.394 112.437 1.00 131.22 ? 726 VAL A N     1 
ATOM   5181 C CA    . VAL A 1 726 ? 145.968 160.549 111.497 1.00 128.71 ? 726 VAL A CA    1 
ATOM   5182 C C     . VAL A 1 726 ? 147.240 160.940 112.238 1.00 128.39 ? 726 VAL A C     1 
ATOM   5183 O O     . VAL A 1 726 ? 148.317 160.382 111.995 1.00 130.81 ? 726 VAL A O     1 
ATOM   5184 C CB    . VAL A 1 726 ? 145.611 161.577 110.409 1.00 127.69 ? 726 VAL A CB    1 
ATOM   5185 C CG1   . VAL A 1 726 ? 146.841 161.935 109.588 1.00 126.42 ? 726 VAL A CG1   1 
ATOM   5186 C CG2   . VAL A 1 726 ? 144.512 161.036 109.510 1.00 119.69 ? 726 VAL A CG2   1 
ATOM   5187 N N     . LEU A 1 727 ? 147.131 161.900 113.161 1.00 128.59 ? 727 LEU A N     1 
ATOM   5188 C CA    . LEU A 1 727 ? 148.294 162.349 113.918 1.00 132.05 ? 727 LEU A CA    1 
ATOM   5189 C C     . LEU A 1 727 ? 148.928 161.199 114.687 1.00 135.90 ? 727 LEU A C     1 
ATOM   5190 O O     . LEU A 1 727 ? 150.139 160.963 114.592 1.00 138.40 ? 727 LEU A O     1 
ATOM   5191 C CB    . LEU A 1 727 ? 147.888 163.469 114.878 1.00 133.72 ? 727 LEU A CB    1 
ATOM   5192 C CG    . LEU A 1 727 ? 147.639 164.865 114.306 1.00 132.61 ? 727 LEU A CG    1 
ATOM   5193 C CD1   . LEU A 1 727 ? 146.749 165.667 115.239 1.00 131.05 ? 727 LEU A CD1   1 
ATOM   5194 C CD2   . LEU A 1 727 ? 148.958 165.583 114.089 1.00 134.87 ? 727 LEU A CD2   1 
ATOM   5195 N N     . ALA A 1 728 ? 148.117 160.463 115.451 1.00 136.33 ? 728 ALA A N     1 
ATOM   5196 C CA    . ALA A 1 728 ? 148.653 159.393 116.283 1.00 142.11 ? 728 ALA A CA    1 
ATOM   5197 C C     . ALA A 1 728 ? 149.264 158.285 115.435 1.00 141.11 ? 728 ALA A C     1 
ATOM   5198 O O     . ALA A 1 728 ? 150.368 157.805 115.724 1.00 138.26 ? 728 ALA A O     1 
ATOM   5199 C CB    . ALA A 1 728 ? 147.555 158.841 117.190 1.00 142.92 ? 728 ALA A CB    1 
ATOM   5200 N N     . ALA A 1 729 ? 148.564 157.868 114.374 1.00 141.29 ? 729 ALA A N     1 
ATOM   5201 C CA    . ALA A 1 729 ? 149.080 156.792 113.535 1.00 140.40 ? 729 ALA A CA    1 
ATOM   5202 C C     . ALA A 1 729 ? 150.381 157.195 112.853 1.00 137.97 ? 729 ALA A C     1 
ATOM   5203 O O     . ALA A 1 729 ? 151.341 156.414 112.822 1.00 138.09 ? 729 ALA A O     1 
ATOM   5204 C CB    . ALA A 1 729 ? 148.031 156.386 112.499 1.00 135.17 ? 729 ALA A CB    1 
ATOM   5205 N N     . ALA A 1 730 ? 150.437 158.415 112.309 1.00 134.74 ? 730 ALA A N     1 
ATOM   5206 C CA    . ALA A 1 730 ? 151.651 158.868 111.643 1.00 128.31 ? 730 ALA A CA    1 
ATOM   5207 C C     . ALA A 1 730 ? 152.809 158.981 112.622 1.00 130.21 ? 730 ALA A C     1 
ATOM   5208 O O     . ALA A 1 730 ? 153.938 158.595 112.300 1.00 132.35 ? 730 ALA A O     1 
ATOM   5209 C CB    . ALA A 1 730 ? 151.400 160.205 110.948 1.00 126.76 ? 730 ALA A CB    1 
ATOM   5210 N N     . ASN A 1 731 ? 152.556 159.512 113.822 1.00 134.00 ? 731 ASN A N     1 
ATOM   5211 C CA    . ASN A 1 731 ? 153.628 159.639 114.803 1.00 138.10 ? 731 ASN A CA    1 
ATOM   5212 C C     . ASN A 1 731 ? 154.143 158.275 115.239 1.00 139.80 ? 731 ASN A C     1 
ATOM   5213 O O     . ASN A 1 731 ? 155.355 158.080 115.384 1.00 141.83 ? 731 ASN A O     1 
ATOM   5214 C CB    . ASN A 1 731 ? 153.152 160.447 116.010 1.00 139.81 ? 731 ASN A CB    1 
ATOM   5215 C CG    . ASN A 1 731 ? 153.351 161.940 115.826 1.00 138.36 ? 731 ASN A CG    1 
ATOM   5216 O OD1   . ASN A 1 731 ? 154.458 162.453 115.986 1.00 137.01 ? 731 ASN A OD1   1 
ATOM   5217 N ND2   . ASN A 1 731 ? 152.277 162.645 115.493 1.00 139.58 ? 731 ASN A ND2   1 
ATOM   5218 N N     . LEU A 1 732 ? 153.239 157.315 115.454 1.00 136.00 ? 732 LEU A N     1 
ATOM   5219 C CA    . LEU A 1 732 ? 153.676 155.973 115.827 1.00 139.79 ? 732 LEU A CA    1 
ATOM   5220 C C     . LEU A 1 732 ? 154.492 155.327 114.713 1.00 140.35 ? 732 LEU A C     1 
ATOM   5221 O O     . LEU A 1 732 ? 155.540 154.719 114.972 1.00 137.07 ? 732 LEU A O     1 
ATOM   5222 C CB    . LEU A 1 732 ? 152.466 155.111 116.186 1.00 140.46 ? 732 LEU A CB    1 
ATOM   5223 C CG    . LEU A 1 732 ? 151.724 155.489 117.468 1.00 140.16 ? 732 LEU A CG    1 
ATOM   5224 C CD1   . LEU A 1 732 ? 150.416 154.726 117.572 1.00 141.35 ? 732 LEU A CD1   1 
ATOM   5225 C CD2   . LEU A 1 732 ? 152.594 155.230 118.686 1.00 140.95 ? 732 LEU A CD2   1 
ATOM   5226 N N     . TYR A 1 733 ? 154.038 155.461 113.463 1.00 139.59 ? 733 TYR A N     1 
ATOM   5227 C CA    . TYR A 1 733 ? 154.791 154.899 112.346 1.00 134.75 ? 733 TYR A CA    1 
ATOM   5228 C C     . TYR A 1 733 ? 156.168 155.543 112.235 1.00 133.60 ? 733 TYR A C     1 
ATOM   5229 O O     . TYR A 1 733 ? 157.165 154.854 111.995 1.00 131.89 ? 733 TYR A O     1 
ATOM   5230 C CB    . TYR A 1 733 ? 154.007 155.072 111.043 1.00 127.70 ? 733 TYR A CB    1 
ATOM   5231 C CG    . TYR A 1 733 ? 154.619 154.376 109.843 1.00 123.96 ? 733 TYR A CG    1 
ATOM   5232 C CD1   . TYR A 1 733 ? 155.704 154.926 109.172 1.00 129.86 ? 733 TYR A CD1   1 
ATOM   5233 C CD2   . TYR A 1 733 ? 154.103 153.178 109.374 1.00 117.21 ? 733 TYR A CD2   1 
ATOM   5234 C CE1   . TYR A 1 733 ? 156.265 154.299 108.081 1.00 127.45 ? 733 TYR A CE1   1 
ATOM   5235 C CE2   . TYR A 1 733 ? 154.657 152.544 108.279 1.00 116.50 ? 733 TYR A CE2   1 
ATOM   5236 C CZ    . TYR A 1 733 ? 155.737 153.110 107.637 1.00 120.86 ? 733 TYR A CZ    1 
ATOM   5237 O OH    . TYR A 1 733 ? 156.295 152.487 106.545 1.00 123.23 ? 733 TYR A OH    1 
ATOM   5238 N N     . ALA A 1 734 ? 156.241 156.866 112.399 1.00 134.99 ? 734 ALA A N     1 
ATOM   5239 C CA    . ALA A 1 734 ? 157.523 157.555 112.305 1.00 135.14 ? 734 ALA A CA    1 
ATOM   5240 C C     . ALA A 1 734 ? 158.465 157.128 113.422 1.00 138.29 ? 734 ALA A C     1 
ATOM   5241 O O     . ALA A 1 734 ? 159.659 156.908 113.185 1.00 141.47 ? 734 ALA A O     1 
ATOM   5242 C CB    . ALA A 1 734 ? 157.308 159.068 112.332 1.00 136.41 ? 734 ALA A CB    1 
ATOM   5243 N N     . GLN A 1 735 ? 157.951 157.007 114.648 1.00 137.42 ? 735 GLN A N     1 
ATOM   5244 C CA    . GLN A 1 735 ? 158.800 156.582 115.755 1.00 140.61 ? 735 GLN A CA    1 
ATOM   5245 C C     . GLN A 1 735 ? 159.249 155.135 115.593 1.00 143.58 ? 735 GLN A C     1 
ATOM   5246 O O     . GLN A 1 735 ? 160.330 154.768 116.068 1.00 144.97 ? 735 GLN A O     1 
ATOM   5247 C CB    . GLN A 1 735 ? 158.072 156.776 117.085 1.00 137.04 ? 735 GLN A CB    1 
ATOM   5248 C CG    . GLN A 1 735 ? 157.811 158.235 117.435 1.00 134.94 ? 735 GLN A CG    1 
ATOM   5249 C CD    . GLN A 1 735 ? 157.282 158.416 118.845 1.00 133.49 ? 735 GLN A CD    1 
ATOM   5250 O OE1   . GLN A 1 735 ? 157.119 157.450 119.589 1.00 130.88 ? 735 GLN A OE1   1 
ATOM   5251 N NE2   . GLN A 1 735 ? 157.012 159.662 119.219 1.00 137.19 ? 735 GLN A NE2   1 
ATOM   5252 N N     . MET A 1 736 ? 158.441 154.301 114.934 1.00 140.34 ? 736 MET A N     1 
ATOM   5253 C CA    . MET A 1 736 ? 158.881 152.943 114.625 1.00 141.38 ? 736 MET A CA    1 
ATOM   5254 C C     . MET A 1 736 ? 159.969 152.945 113.557 1.00 141.21 ? 736 MET A C     1 
ATOM   5255 O O     . MET A 1 736 ? 160.997 152.271 113.699 1.00 142.10 ? 736 MET A O     1 
ATOM   5256 C CB    . MET A 1 736 ? 157.695 152.093 114.170 1.00 143.29 ? 736 MET A CB    1 
ATOM   5257 C CG    . MET A 1 736 ? 158.083 150.989 113.196 1.00 144.98 ? 736 MET A CG    1 
ATOM   5258 S SD    . MET A 1 736 ? 156.678 150.075 112.541 1.00 138.18 ? 736 MET A SD    1 
ATOM   5259 C CE    . MET A 1 736 ? 156.180 149.168 113.996 1.00 130.48 ? 736 MET A CE    1 
ATOM   5260 N N     . HIS A 1 737 ? 159.759 153.701 112.481 1.00 140.05 ? 737 HIS A N     1 
ATOM   5261 C CA    . HIS A 1 737 ? 160.638 153.691 111.320 1.00 142.35 ? 737 HIS A CA    1 
ATOM   5262 C C     . HIS A 1 737 ? 161.923 154.479 111.536 1.00 143.20 ? 737 HIS A C     1 
ATOM   5263 O O     . HIS A 1 737 ? 162.851 154.353 110.730 1.00 143.02 ? 737 HIS A O     1 
ATOM   5264 C CB    . HIS A 1 737 ? 159.883 154.252 110.109 1.00 144.12 ? 737 HIS A CB    1 
ATOM   5265 C CG    . HIS A 1 737 ? 160.595 154.068 108.805 1.00 148.11 ? 737 HIS A CG    1 
ATOM   5266 N ND1   . HIS A 1 737 ? 160.480 154.964 107.765 1.00 147.89 ? 737 HIS A ND1   1 
ATOM   5267 C CD2   . HIS A 1 737 ? 161.421 153.088 108.369 1.00 149.48 ? 737 HIS A CD2   1 
ATOM   5268 C CE1   . HIS A 1 737 ? 161.210 154.548 106.745 1.00 148.95 ? 737 HIS A CE1   1 
ATOM   5269 N NE2   . HIS A 1 737 ? 161.791 153.412 107.086 1.00 150.84 ? 737 HIS A NE2   1 
ATOM   5270 N N     . GLY A 1 738 ? 162.009 155.268 112.603 1.00 143.27 ? 738 GLY A N     1 
ATOM   5271 C CA    . GLY A 1 738 ? 163.128 156.160 112.806 1.00 142.27 ? 738 GLY A CA    1 
ATOM   5272 C C     . GLY A 1 738 ? 162.947 157.543 112.223 1.00 140.10 ? 738 GLY A C     1 
ATOM   5273 O O     . GLY A 1 738 ? 163.827 158.395 112.405 1.00 140.11 ? 738 GLY A O     1 
ATOM   5274 N N     . LEU A 1 739 ? 161.840 157.794 111.529 1.00 140.23 ? 739 LEU A N     1 
ATOM   5275 C CA    . LEU A 1 739 ? 161.564 159.124 111.017 1.00 139.43 ? 739 LEU A CA    1 
ATOM   5276 C C     . LEU A 1 739 ? 161.223 160.069 112.169 1.00 139.87 ? 739 LEU A C     1 
ATOM   5277 O O     . LEU A 1 739 ? 160.704 159.640 113.203 1.00 138.37 ? 739 LEU A O     1 
ATOM   5278 C CB    . LEU A 1 739 ? 160.412 159.084 110.018 1.00 139.61 ? 739 LEU A CB    1 
ATOM   5279 C CG    . LEU A 1 739 ? 160.700 158.430 108.666 1.00 138.63 ? 739 LEU A CG    1 
ATOM   5280 C CD1   . LEU A 1 739 ? 159.427 158.332 107.841 1.00 134.06 ? 739 LEU A CD1   1 
ATOM   5281 C CD2   . LEU A 1 739 ? 161.767 159.210 107.915 1.00 137.02 ? 739 LEU A CD2   1 
ATOM   5282 N N     . PRO A 1 740 ? 161.513 161.362 112.018 1.00 140.36 ? 740 PRO A N     1 
ATOM   5283 C CA    . PRO A 1 740 ? 161.225 162.310 113.103 1.00 137.48 ? 740 PRO A CA    1 
ATOM   5284 C C     . PRO A 1 740 ? 159.734 162.594 113.207 1.00 132.76 ? 740 PRO A C     1 
ATOM   5285 O O     . PRO A 1 740 ? 159.084 162.954 112.223 1.00 127.30 ? 740 PRO A O     1 
ATOM   5286 C CB    . PRO A 1 740 ? 162.012 163.561 112.696 1.00 134.69 ? 740 PRO A CB    1 
ATOM   5287 C CG    . PRO A 1 740 ? 162.094 163.474 111.209 1.00 132.77 ? 740 PRO A CG    1 
ATOM   5288 C CD    . PRO A 1 740 ? 162.200 162.008 110.886 1.00 136.44 ? 740 PRO A CD    1 
ATOM   5289 N N     . GLY A 1 741 ? 159.196 162.427 114.412 1.00 131.81 ? 741 GLY A N     1 
ATOM   5290 C CA    . GLY A 1 741 ? 157.809 162.761 114.649 1.00 131.51 ? 741 GLY A CA    1 
ATOM   5291 C C     . GLY A 1 741 ? 157.587 164.258 114.728 1.00 129.70 ? 741 GLY A C     1 
ATOM   5292 O O     . GLY A 1 741 ? 158.515 165.052 114.888 1.00 130.32 ? 741 GLY A O     1 
ATOM   5293 N N     . SER A 1 742 ? 156.321 164.649 114.610 1.00 130.64 ? 742 SER A N     1 
ATOM   5294 C CA    . SER A 1 742 ? 155.959 166.058 114.636 1.00 129.02 ? 742 SER A CA    1 
ATOM   5295 C C     . SER A 1 742 ? 154.573 166.207 115.242 1.00 135.90 ? 742 SER A C     1 
ATOM   5296 O O     . SER A 1 742 ? 153.759 165.281 115.203 1.00 138.57 ? 742 SER A O     1 
ATOM   5297 C CB    . SER A 1 742 ? 155.997 166.672 113.232 1.00 123.03 ? 742 SER A CB    1 
ATOM   5298 O OG    . SER A 1 742 ? 155.768 168.068 113.283 1.00 126.40 ? 742 SER A OG    1 
ATOM   5299 N N     . GLN A 1 743 ? 154.314 167.388 115.806 1.00 136.61 ? 743 GLN A N     1 
ATOM   5300 C CA    . GLN A 1 743 ? 153.036 167.686 116.440 1.00 136.59 ? 743 GLN A CA    1 
ATOM   5301 C C     . GLN A 1 743 ? 152.351 168.907 115.840 1.00 134.52 ? 743 GLN A C     1 
ATOM   5302 O O     . GLN A 1 743 ? 151.399 169.423 116.436 1.00 135.26 ? 743 GLN A O     1 
ATOM   5303 C CB    . GLN A 1 743 ? 153.219 167.886 117.949 1.00 135.71 ? 743 GLN A CB    1 
ATOM   5304 C CG    . GLN A 1 743 ? 153.899 166.729 118.667 1.00 136.74 ? 743 GLN A CG    1 
ATOM   5305 C CD    . GLN A 1 743 ? 155.412 166.849 118.672 1.00 135.59 ? 743 GLN A CD    1 
ATOM   5306 O OE1   . GLN A 1 743 ? 155.972 167.816 118.155 1.00 130.79 ? 743 GLN A OE1   1 
ATOM   5307 N NE2   . GLN A 1 743 ? 156.082 165.866 119.263 1.00 138.32 ? 743 GLN A NE2   1 
ATOM   5308 N N     . ASP A 1 744 ? 152.806 169.386 114.684 1.00 135.94 ? 744 ASP A N     1 
ATOM   5309 C CA    . ASP A 1 744 ? 152.237 170.580 114.056 1.00 140.11 ? 744 ASP A CA    1 
ATOM   5310 C C     . ASP A 1 744 ? 150.914 170.211 113.392 1.00 137.86 ? 744 ASP A C     1 
ATOM   5311 O O     . ASP A 1 744 ? 150.860 169.812 112.228 1.00 136.54 ? 744 ASP A O     1 
ATOM   5312 C CB    . ASP A 1 744 ? 153.222 171.201 113.067 1.00 140.75 ? 744 ASP A CB    1 
ATOM   5313 C CG    . ASP A 1 744 ? 153.819 170.190 112.088 1.00 141.05 ? 744 ASP A CG    1 
ATOM   5314 O OD1   . ASP A 1 744 ? 153.405 169.012 112.071 1.00 138.61 ? 744 ASP A OD1   1 
ATOM   5315 O OD2   . ASP A 1 744 ? 154.721 170.588 111.321 1.00 141.31 ? 744 ASP A OD2   1 
ATOM   5316 N N     . GLN A 1 745 ? 149.823 170.359 114.147 1.00 136.42 ? 745 GLN A N     1 
ATOM   5317 C CA    . GLN A 1 745 ? 148.511 169.991 113.626 1.00 135.85 ? 745 GLN A CA    1 
ATOM   5318 C C     . GLN A 1 745 ? 148.098 170.870 112.451 1.00 134.75 ? 745 GLN A C     1 
ATOM   5319 O O     . GLN A 1 745 ? 147.436 170.388 111.526 1.00 134.51 ? 745 GLN A O     1 
ATOM   5320 C CB    . GLN A 1 745 ? 147.459 170.065 114.734 1.00 135.24 ? 745 GLN A CB    1 
ATOM   5321 C CG    . GLN A 1 745 ? 147.794 169.259 115.981 1.00 134.83 ? 745 GLN A CG    1 
ATOM   5322 C CD    . GLN A 1 745 ? 148.510 170.085 117.030 1.00 137.77 ? 745 GLN A CD    1 
ATOM   5323 O OE1   . GLN A 1 745 ? 148.734 171.282 116.847 1.00 138.32 ? 745 GLN A OE1   1 
ATOM   5324 N NE2   . GLN A 1 745 ? 148.873 169.450 118.139 1.00 137.93 ? 745 GLN A NE2   1 
ATOM   5325 N N     . THR A 1 746 ? 148.472 172.152 112.467 1.00 135.24 ? 746 THR A N     1 
ATOM   5326 C CA    . THR A 1 746 ? 148.112 173.042 111.366 1.00 135.34 ? 746 THR A CA    1 
ATOM   5327 C C     . THR A 1 746 ? 148.813 172.635 110.075 1.00 134.88 ? 746 THR A C     1 
ATOM   5328 O O     . THR A 1 746 ? 148.184 172.549 109.012 1.00 134.66 ? 746 THR A O     1 
ATOM   5329 C CB    . THR A 1 746 ? 148.447 174.489 111.731 1.00 136.17 ? 746 THR A CB    1 
ATOM   5330 O OG1   . THR A 1 746 ? 149.845 174.601 112.023 1.00 136.11 ? 746 THR A OG1   1 
ATOM   5331 C CG2   . THR A 1 746 ? 147.644 174.930 112.946 1.00 135.12 ? 746 THR A CG2   1 
ATOM   5332 N N     . ALA A 1 747 ? 150.119 172.369 110.148 1.00 134.83 ? 747 ALA A N     1 
ATOM   5333 C CA    . ALA A 1 747 ? 150.838 171.909 108.967 1.00 132.03 ? 747 ALA A CA    1 
ATOM   5334 C C     . ALA A 1 747 ? 150.335 170.548 108.506 1.00 129.82 ? 747 ALA A C     1 
ATOM   5335 O O     . ALA A 1 747 ? 150.235 170.299 107.299 1.00 129.66 ? 747 ALA A O     1 
ATOM   5336 C CB    . ALA A 1 747 ? 152.339 171.855 109.250 1.00 128.10 ? 747 ALA A CB    1 
ATOM   5337 N N     . LEU A 1 748 ? 149.997 169.666 109.449 1.00 127.71 ? 748 LEU A N     1 
ATOM   5338 C CA    . LEU A 1 748 ? 149.489 168.349 109.086 1.00 125.59 ? 748 LEU A CA    1 
ATOM   5339 C C     . LEU A 1 748 ? 148.146 168.448 108.370 1.00 128.46 ? 748 LEU A C     1 
ATOM   5340 O O     . LEU A 1 748 ? 147.919 167.756 107.372 1.00 127.95 ? 748 LEU A O     1 
ATOM   5341 C CB    . LEU A 1 748 ? 149.375 167.473 110.333 1.00 123.89 ? 748 LEU A CB    1 
ATOM   5342 C CG    . LEU A 1 748 ? 149.070 165.995 110.093 1.00 125.65 ? 748 LEU A CG    1 
ATOM   5343 C CD1   . LEU A 1 748 ? 150.159 165.125 110.699 1.00 126.90 ? 748 LEU A CD1   1 
ATOM   5344 C CD2   . LEU A 1 748 ? 147.710 165.631 110.659 1.00 124.91 ? 748 LEU A CD2   1 
ATOM   5345 N N     . ARG A 1 749 ? 147.242 169.305 108.855 1.00 129.99 ? 749 ARG A N     1 
ATOM   5346 C CA    . ARG A 1 749 ? 145.956 169.460 108.182 1.00 126.95 ? 749 ARG A CA    1 
ATOM   5347 C C     . ARG A 1 749 ? 146.110 170.161 106.837 1.00 126.03 ? 749 ARG A C     1 
ATOM   5348 O O     . ARG A 1 749 ? 145.371 169.855 105.893 1.00 124.00 ? 749 ARG A O     1 
ATOM   5349 C CB    . ARG A 1 749 ? 144.964 170.204 109.079 1.00 121.09 ? 749 ARG A CB    1 
ATOM   5350 C CG    . ARG A 1 749 ? 145.270 171.668 109.304 1.00 122.64 ? 749 ARG A CG    1 
ATOM   5351 C CD    . ARG A 1 749 ? 144.305 172.298 110.291 1.00 123.66 ? 749 ARG A CD    1 
ATOM   5352 N NE    . ARG A 1 749 ? 144.570 173.720 110.476 1.00 129.24 ? 749 ARG A NE    1 
ATOM   5353 C CZ    . ARG A 1 749 ? 143.895 174.506 111.303 1.00 127.73 ? 749 ARG A CZ    1 
ATOM   5354 N NH1   . ARG A 1 749 ? 142.903 174.041 112.044 1.00 129.60 ? 749 ARG A NH1   1 
ATOM   5355 N NH2   . ARG A 1 749 ? 144.223 175.792 111.389 1.00 122.36 ? 749 ARG A NH2   1 
ATOM   5356 N N     . GLY A 1 750 ? 147.064 171.090 106.723 1.00 130.39 ? 750 GLY A N     1 
ATOM   5357 C CA    . GLY A 1 750 ? 147.362 171.663 105.420 1.00 130.70 ? 750 GLY A CA    1 
ATOM   5358 C C     . GLY A 1 750 ? 147.848 170.623 104.430 1.00 130.61 ? 750 GLY A C     1 
ATOM   5359 O O     . GLY A 1 750 ? 147.448 170.624 103.263 1.00 133.29 ? 750 GLY A O     1 
ATOM   5360 N N     . LEU A 1 751 ? 148.717 169.717 104.882 1.00 129.08 ? 751 LEU A N     1 
ATOM   5361 C CA    . LEU A 1 751 ? 149.155 168.622 104.021 1.00 126.59 ? 751 LEU A CA    1 
ATOM   5362 C C     . LEU A 1 751 ? 147.996 167.695 103.673 1.00 128.26 ? 751 LEU A C     1 
ATOM   5363 O O     . LEU A 1 751 ? 147.916 167.183 102.550 1.00 128.81 ? 751 LEU A O     1 
ATOM   5364 C CB    . LEU A 1 751 ? 150.285 167.846 104.695 1.00 119.86 ? 751 LEU A CB    1 
ATOM   5365 C CG    . LEU A 1 751 ? 151.571 168.635 104.940 1.00 115.83 ? 751 LEU A CG    1 
ATOM   5366 C CD1   . LEU A 1 751 ? 152.515 167.859 105.843 1.00 117.03 ? 751 LEU A CD1   1 
ATOM   5367 C CD2   . LEU A 1 751 ? 152.248 168.984 103.624 1.00 113.85 ? 751 LEU A CD2   1 
ATOM   5368 N N     . LEU A 1 752 ? 147.092 167.459 104.630 1.00 127.79 ? 752 LEU A N     1 
ATOM   5369 C CA    . LEU A 1 752 ? 145.948 166.588 104.373 1.00 124.18 ? 752 LEU A CA    1 
ATOM   5370 C C     . LEU A 1 752 ? 145.027 167.171 103.310 1.00 126.11 ? 752 LEU A C     1 
ATOM   5371 O O     . LEU A 1 752 ? 144.581 166.455 102.407 1.00 131.47 ? 752 LEU A O     1 
ATOM   5372 C CB    . LEU A 1 752 ? 145.167 166.339 105.663 1.00 120.89 ? 752 LEU A CB    1 
ATOM   5373 C CG    . LEU A 1 752 ? 145.758 165.367 106.683 1.00 122.84 ? 752 LEU A CG    1 
ATOM   5374 C CD1   . LEU A 1 752 ? 144.782 165.150 107.830 1.00 122.99 ? 752 LEU A CD1   1 
ATOM   5375 C CD2   . LEU A 1 752 ? 146.118 164.046 106.024 1.00 118.00 ? 752 LEU A CD2   1 
ATOM   5376 N N     . ASN A 1 753 ? 144.731 168.466 103.396 1.00 124.09 ? 753 ASN A N     1 
ATOM   5377 C CA    . ASN A 1 753 ? 143.827 169.075 102.428 1.00 125.40 ? 753 ASN A CA    1 
ATOM   5378 C C     . ASN A 1 753 ? 144.535 169.553 101.168 1.00 126.16 ? 753 ASN A C     1 
ATOM   5379 O O     . ASN A 1 753 ? 143.864 170.006 100.235 1.00 125.50 ? 753 ASN A O     1 
ATOM   5380 C CB    . ASN A 1 753 ? 143.047 170.237 103.065 1.00 128.62 ? 753 ASN A CB    1 
ATOM   5381 C CG    . ASN A 1 753 ? 143.946 171.307 103.661 1.00 131.50 ? 753 ASN A CG    1 
ATOM   5382 O OD1   . ASN A 1 753 ? 144.968 171.676 103.087 1.00 133.16 ? 753 ASN A OD1   1 
ATOM   5383 N ND2   . ASN A 1 753 ? 143.556 171.818 104.823 1.00 127.70 ? 753 ASN A ND2   1 
ATOM   5384 N N     . LEU A 1 754 ? 145.865 169.465 101.116 1.00 128.88 ? 754 LEU A N     1 
ATOM   5385 C CA    . LEU A 1 754 ? 146.580 169.797 99.889  1.00 130.63 ? 754 LEU A CA    1 
ATOM   5386 C C     . LEU A 1 754 ? 146.709 168.590 98.965  1.00 132.96 ? 754 LEU A C     1 
ATOM   5387 O O     . LEU A 1 754 ? 146.591 168.728 97.743  1.00 133.02 ? 754 LEU A O     1 
ATOM   5388 C CB    . LEU A 1 754 ? 147.959 170.368 100.223 1.00 129.42 ? 754 LEU A CB    1 
ATOM   5389 C CG    . LEU A 1 754 ? 148.137 171.872 99.997  1.00 126.91 ? 754 LEU A CG    1 
ATOM   5390 C CD1   . LEU A 1 754 ? 148.091 172.200 98.511  1.00 123.56 ? 754 LEU A CD1   1 
ATOM   5391 C CD2   . LEU A 1 754 ? 147.082 172.665 100.752 1.00 126.63 ? 754 LEU A CD2   1 
ATOM   5392 N N     . LEU A 1 755 ? 146.949 167.403 99.525  1.00 135.71 ? 755 LEU A N     1 
ATOM   5393 C CA    . LEU A 1 755 ? 147.159 166.182 98.745  1.00 139.47 ? 755 LEU A CA    1 
ATOM   5394 C C     . LEU A 1 755 ? 146.275 165.064 99.288  1.00 141.12 ? 755 LEU A C     1 
ATOM   5395 O O     . LEU A 1 755 ? 146.747 164.182 100.018 1.00 138.22 ? 755 LEU A O     1 
ATOM   5396 C CB    . LEU A 1 755 ? 148.634 165.774 98.759  1.00 138.40 ? 755 LEU A CB    1 
ATOM   5397 C CG    . LEU A 1 755 ? 149.056 164.595 97.878  1.00 133.81 ? 755 LEU A CG    1 
ATOM   5398 C CD1   . LEU A 1 755 ? 148.766 164.880 96.411  1.00 132.57 ? 755 LEU A CD1   1 
ATOM   5399 C CD2   . LEU A 1 755 ? 150.528 164.263 98.085  1.00 117.77 ? 755 LEU A CD2   1 
ATOM   5400 N N     . PRO A 1 756 ? 144.984 165.077 98.966  1.00 140.01 ? 756 PRO A N     1 
ATOM   5401 C CA    . PRO A 1 756 ? 144.109 163.968 99.349  1.00 135.73 ? 756 PRO A CA    1 
ATOM   5402 C C     . PRO A 1 756 ? 144.003 162.913 98.254  1.00 135.48 ? 756 PRO A C     1 
ATOM   5403 O O     . PRO A 1 756 ? 144.309 163.152 97.084  1.00 136.01 ? 756 PRO A O     1 
ATOM   5404 C CB    . PRO A 1 756 ? 142.759 164.664 99.563  1.00 131.54 ? 756 PRO A CB    1 
ATOM   5405 C CG    . PRO A 1 756 ? 142.773 165.757 98.547  1.00 130.15 ? 756 PRO A CG    1 
ATOM   5406 C CD    . PRO A 1 756 ? 144.217 166.199 98.394  1.00 132.93 ? 756 PRO A CD    1 
ATOM   5407 N N     . LEU A 1 757 ? 143.561 161.726 98.663  1.00 133.11 ? 757 LEU A N     1 
ATOM   5408 C CA    . LEU A 1 757 ? 143.308 160.662 97.705  1.00 132.24 ? 757 LEU A CA    1 
ATOM   5409 C C     . LEU A 1 757 ? 142.095 161.005 96.841  1.00 134.03 ? 757 LEU A C     1 
ATOM   5410 O O     . LEU A 1 757 ? 141.139 161.626 97.315  1.00 130.69 ? 757 LEU A O     1 
ATOM   5411 C CB    . LEU A 1 757 ? 143.073 159.333 98.419  1.00 125.78 ? 757 LEU A CB    1 
ATOM   5412 C CG    . LEU A 1 757 ? 144.307 158.559 98.889  1.00 119.69 ? 757 LEU A CG    1 
ATOM   5413 C CD1   . LEU A 1 757 ? 143.897 157.266 99.573  1.00 108.36 ? 757 LEU A CD1   1 
ATOM   5414 C CD2   . LEU A 1 757 ? 145.246 158.278 97.726  1.00 122.55 ? 757 LEU A CD2   1 
ATOM   5415 N N     . PRO A 1 758 ? 142.109 160.612 95.564  1.00 136.33 ? 758 PRO A N     1 
ATOM   5416 C CA    . PRO A 1 758 ? 140.952 160.923 94.707  1.00 134.35 ? 758 PRO A CA    1 
ATOM   5417 C C     . PRO A 1 758 ? 139.719 160.106 95.048  1.00 134.66 ? 758 PRO A C     1 
ATOM   5418 O O     . PRO A 1 758 ? 138.609 160.654 95.073  1.00 136.13 ? 758 PRO A O     1 
ATOM   5419 C CB    . PRO A 1 758 ? 141.474 160.616 93.297  1.00 129.75 ? 758 PRO A CB    1 
ATOM   5420 C CG    . PRO A 1 758 ? 142.537 159.590 93.509  1.00 129.16 ? 758 PRO A CG    1 
ATOM   5421 C CD    . PRO A 1 758 ? 143.186 159.932 94.823  1.00 132.85 ? 758 PRO A CD    1 
ATOM   5422 N N     . ASP A 1 759 ? 139.876 158.812 95.312  1.00 131.72 ? 759 ASP A N     1 
ATOM   5423 C CA    . ASP A 1 759 ? 138.759 157.944 95.652  1.00 124.80 ? 759 ASP A CA    1 
ATOM   5424 C C     . ASP A 1 759 ? 139.284 156.782 96.479  1.00 119.60 ? 759 ASP A C     1 
ATOM   5425 O O     . ASP A 1 759 ? 140.463 156.427 96.363  1.00 119.24 ? 759 ASP A O     1 
ATOM   5426 C CB    . ASP A 1 759 ? 138.043 157.425 94.395  1.00 122.79 ? 759 ASP A CB    1 
ATOM   5427 C CG    . ASP A 1 759 ? 138.933 156.549 93.534  1.00 120.81 ? 759 ASP A CG    1 
ATOM   5428 O OD1   . ASP A 1 759 ? 139.025 155.335 93.813  1.00 117.56 ? 759 ASP A OD1   1 
ATOM   5429 O OD2   . ASP A 1 759 ? 139.542 157.074 92.578  1.00 122.04 ? 759 ASP A OD2   1 
ATOM   5430 N N     . PRO A 1 760 ? 138.447 156.180 97.328  1.00 118.16 ? 760 PRO A N     1 
ATOM   5431 C CA    . PRO A 1 760 ? 138.896 155.043 98.140  1.00 112.56 ? 760 PRO A CA    1 
ATOM   5432 C C     . PRO A 1 760 ? 138.711 153.675 97.502  1.00 111.82 ? 760 PRO A C     1 
ATOM   5433 O O     . PRO A 1 760 ? 139.211 152.688 98.060  1.00 109.27 ? 760 PRO A O     1 
ATOM   5434 C CB    . PRO A 1 760 ? 138.020 155.171 99.393  1.00 106.41 ? 760 PRO A CB    1 
ATOM   5435 C CG    . PRO A 1 760 ? 136.744 155.736 98.872  1.00 111.82 ? 760 PRO A CG    1 
ATOM   5436 C CD    . PRO A 1 760 ? 137.115 156.661 97.740  1.00 116.14 ? 760 PRO A CD    1 
ATOM   5437 N N     . GLN A 1 761 ? 138.018 153.578 96.366  1.00 112.25 ? 761 GLN A N     1 
ATOM   5438 C CA    . GLN A 1 761 ? 137.787 152.285 95.734  1.00 108.17 ? 761 GLN A CA    1 
ATOM   5439 C C     . GLN A 1 761 ? 138.998 151.772 94.966  1.00 107.11 ? 761 GLN A C     1 
ATOM   5440 O O     . GLN A 1 761 ? 139.121 150.558 94.772  1.00 107.00 ? 761 GLN A O     1 
ATOM   5441 C CB    . GLN A 1 761 ? 136.585 152.366 94.790  1.00 102.69 ? 761 GLN A CB    1 
ATOM   5442 C CG    . GLN A 1 761 ? 135.244 152.482 95.492  1.00 101.56 ? 761 GLN A CG    1 
ATOM   5443 C CD    . GLN A 1 761 ? 134.823 151.189 96.163  1.00 107.62 ? 761 GLN A CD    1 
ATOM   5444 O OE1   . GLN A 1 761 ? 135.355 150.119 95.867  1.00 107.15 ? 761 GLN A OE1   1 
ATOM   5445 N NE2   . GLN A 1 761 ? 133.860 151.282 97.074  1.00 112.71 ? 761 GLN A NE2   1 
ATOM   5446 N N     . ASN A 1 762 ? 139.895 152.661 94.536  1.00 104.47 ? 762 ASN A N     1 
ATOM   5447 C CA    . ASN A 1 762 ? 141.034 152.260 93.719  1.00 101.38 ? 762 ASN A CA    1 
ATOM   5448 C C     . ASN A 1 762 ? 142.042 151.412 94.481  1.00 106.89 ? 762 ASN A C     1 
ATOM   5449 O O     . ASN A 1 762 ? 142.934 150.829 93.852  1.00 113.72 ? 762 ASN A O     1 
ATOM   5450 C CB    . ASN A 1 762 ? 141.728 153.494 93.144  1.00 104.18 ? 762 ASN A CB    1 
ATOM   5451 C CG    . ASN A 1 762 ? 142.450 154.303 94.202  1.00 110.55 ? 762 ASN A CG    1 
ATOM   5452 O OD1   . ASN A 1 762 ? 142.046 154.332 95.363  1.00 109.50 ? 762 ASN A OD1   1 
ATOM   5453 N ND2   . ASN A 1 762 ? 143.529 154.967 93.804  1.00 115.05 ? 762 ASN A ND2   1 
ATOM   5454 N N     . LEU A 1 763 ? 141.917 151.319 95.808  1.00 105.61 ? 763 LEU A N     1 
ATOM   5455 C CA    . LEU A 1 763 ? 142.833 150.518 96.613  1.00 101.92 ? 763 LEU A CA    1 
ATOM   5456 C C     . LEU A 1 763 ? 142.887 149.059 96.184  1.00 103.26 ? 763 LEU A C     1 
ATOM   5457 O O     . LEU A 1 763 ? 143.772 148.334 96.647  1.00 102.69 ? 763 LEU A O     1 
ATOM   5458 C CB    . LEU A 1 763 ? 142.444 150.596 98.090  1.00 93.69  ? 763 LEU A CB    1 
ATOM   5459 C CG    . LEU A 1 763 ? 142.713 151.922 98.797  1.00 91.71  ? 763 LEU A CG    1 
ATOM   5460 C CD1   . LEU A 1 763 ? 142.379 151.814 100.275 1.00 83.62  ? 763 LEU A CD1   1 
ATOM   5461 C CD2   . LEU A 1 763 ? 144.160 152.338 98.597  1.00 96.52  ? 763 LEU A CD2   1 
ATOM   5462 N N     . ASP A 1 764 ? 141.967 148.610 95.325  1.00 104.73 ? 764 ASP A N     1 
ATOM   5463 C CA    . ASP A 1 764 ? 142.051 147.255 94.793  1.00 103.64 ? 764 ASP A CA    1 
ATOM   5464 C C     . ASP A 1 764 ? 143.342 147.038 94.020  1.00 99.81  ? 764 ASP A C     1 
ATOM   5465 O O     . ASP A 1 764 ? 143.876 145.923 94.006  1.00 103.71 ? 764 ASP A O     1 
ATOM   5466 C CB    . ASP A 1 764 ? 140.846 146.964 93.898  1.00 106.97 ? 764 ASP A CB    1 
ATOM   5467 C CG    . ASP A 1 764 ? 139.541 146.932 94.666  1.00 110.30 ? 764 ASP A CG    1 
ATOM   5468 O OD1   . ASP A 1 764 ? 139.579 147.050 95.908  1.00 109.10 ? 764 ASP A OD1   1 
ATOM   5469 O OD2   . ASP A 1 764 ? 138.477 146.789 94.028  1.00 110.64 ? 764 ASP A OD2   1 
ATOM   5470 N N     . ARG A 1 765 ? 143.861 148.081 93.373  1.00 94.31  ? 765 ARG A N     1 
ATOM   5471 C CA    . ARG A 1 765 ? 145.098 147.942 92.616  1.00 95.72  ? 765 ARG A CA    1 
ATOM   5472 C C     . ARG A 1 765 ? 146.332 147.860 93.504  1.00 101.01 ? 765 ARG A C     1 
ATOM   5473 O O     . ARG A 1 765 ? 147.415 147.547 93.000  1.00 103.67 ? 765 ARG A O     1 
ATOM   5474 C CB    . ARG A 1 765 ? 145.258 149.110 91.640  1.00 97.61  ? 765 ARG A CB    1 
ATOM   5475 C CG    . ARG A 1 765 ? 145.710 150.403 92.300  1.00 107.48 ? 765 ARG A CG    1 
ATOM   5476 C CD    . ARG A 1 765 ? 145.914 151.512 91.282  1.00 106.49 ? 765 ARG A CD    1 
ATOM   5477 N NE    . ARG A 1 765 ? 146.450 152.720 91.897  1.00 107.03 ? 765 ARG A NE    1 
ATOM   5478 C CZ    . ARG A 1 765 ? 147.743 152.982 92.030  1.00 106.97 ? 765 ARG A CZ    1 
ATOM   5479 N NH1   . ARG A 1 765 ? 148.667 152.141 91.596  1.00 107.91 ? 765 ARG A NH1   1 
ATOM   5480 N NH2   . ARG A 1 765 ? 148.119 154.117 92.613  1.00 106.74 ? 765 ARG A NH2   1 
ATOM   5481 N N     . ILE A 1 766 ? 146.199 148.133 94.801  1.00 99.54  ? 766 ILE A N     1 
ATOM   5482 C CA    . ILE A 1 766 ? 147.351 148.209 95.692  1.00 101.79 ? 766 ILE A CA    1 
ATOM   5483 C C     . ILE A 1 766 ? 147.223 147.183 96.813  1.00 108.76 ? 766 ILE A C     1 
ATOM   5484 O O     . ILE A 1 766 ? 148.225 146.638 97.290  1.00 112.82 ? 766 ILE A O     1 
ATOM   5485 C CB    . ILE A 1 766 ? 147.500 149.642 96.239  1.00 102.81 ? 766 ILE A CB    1 
ATOM   5486 C CG1   . ILE A 1 766 ? 148.354 150.483 95.289  1.00 102.17 ? 766 ILE A CG1   1 
ATOM   5487 C CG2   . ILE A 1 766 ? 148.068 149.656 97.652  1.00 106.40 ? 766 ILE A CG2   1 
ATOM   5488 C CD1   . ILE A 1 766 ? 149.767 149.978 95.139  1.00 98.92  ? 766 ILE A CD1   1 
ATOM   5489 N N     . PHE A 1 767 ? 145.991 146.871 97.203  1.00 109.66 ? 767 PHE A N     1 
ATOM   5490 C CA    . PHE A 1 767 ? 145.717 145.960 98.307  1.00 112.90 ? 767 PHE A CA    1 
ATOM   5491 C C     . PHE A 1 767 ? 145.075 144.688 97.776  1.00 116.14 ? 767 PHE A C     1 
ATOM   5492 O O     . PHE A 1 767 ? 144.032 144.741 97.115  1.00 118.18 ? 767 PHE A O     1 
ATOM   5493 C CB    . PHE A 1 767 ? 144.807 146.619 99.346  1.00 104.87 ? 767 PHE A CB    1 
ATOM   5494 C CG    . PHE A 1 767 ? 145.476 147.706 100.133 1.00 99.46  ? 767 PHE A CG    1 
ATOM   5495 C CD1   . PHE A 1 767 ? 146.824 147.629 100.435 1.00 105.18 ? 767 PHE A CD1   1 
ATOM   5496 C CD2   . PHE A 1 767 ? 144.759 148.806 100.566 1.00 99.45  ? 767 PHE A CD2   1 
ATOM   5497 C CE1   . PHE A 1 767 ? 147.445 148.628 101.158 1.00 106.72 ? 767 PHE A CE1   1 
ATOM   5498 C CE2   . PHE A 1 767 ? 145.374 149.811 101.290 1.00 101.82 ? 767 PHE A CE2   1 
ATOM   5499 C CZ    . PHE A 1 767 ? 146.720 149.721 101.586 1.00 102.79 ? 767 PHE A CZ    1 
ATOM   5500 N N     . ALA A 1 768 ? 145.693 143.551 98.075  1.00 116.00 ? 768 ALA A N     1 
ATOM   5501 C CA    . ALA A 1 768 ? 145.210 142.260 97.615  1.00 117.55 ? 768 ALA A CA    1 
ATOM   5502 C C     . ALA A 1 768 ? 144.221 141.669 98.612  1.00 121.53 ? 768 ALA A C     1 
ATOM   5503 O O     . ALA A 1 768 ? 144.307 141.904 99.821  1.00 123.11 ? 768 ALA A O     1 
ATOM   5504 C CB    . ALA A 1 768 ? 146.373 141.294 97.397  1.00 122.08 ? 768 ALA A CB    1 
ATOM   5505 N N     . SER A 1 769 ? 143.276 140.897 98.086  1.00 123.99 ? 769 SER A N     1 
ATOM   5506 C CA    . SER A 1 769 ? 142.232 140.299 98.901  1.00 125.55 ? 769 SER A CA    1 
ATOM   5507 C C     . SER A 1 769 ? 142.777 139.119 99.701  1.00 129.26 ? 769 SER A C     1 
ATOM   5508 O O     . SER A 1 769 ? 143.836 138.562 99.398  1.00 133.82 ? 769 SER A O     1 
ATOM   5509 C CB    . SER A 1 769 ? 141.069 139.846 98.018  1.00 126.56 ? 769 SER A CB    1 
ATOM   5510 O OG    . SER A 1 769 ? 140.084 139.158 98.767  1.00 130.84 ? 769 SER A OG    1 
ATOM   5511 N N     . GLU A 1 770 ? 142.034 138.742 100.745 1.00 125.44 ? 770 GLU A N     1 
ATOM   5512 C CA    . GLU A 1 770 ? 142.382 137.542 101.496 1.00 126.49 ? 770 GLU A CA    1 
ATOM   5513 C C     . GLU A 1 770 ? 142.306 136.297 100.622 1.00 133.15 ? 770 GLU A C     1 
ATOM   5514 O O     . GLU A 1 770 ? 143.018 135.318 100.873 1.00 137.60 ? 770 GLU A O     1 
ATOM   5515 C CB    . GLU A 1 770 ? 141.469 137.394 102.714 1.00 126.68 ? 770 GLU A CB    1 
ATOM   5516 C CG    . GLU A 1 770 ? 141.852 138.265 103.907 1.00 133.81 ? 770 GLU A CG    1 
ATOM   5517 C CD    . GLU A 1 770 ? 141.355 139.693 103.785 1.00 134.10 ? 770 GLU A CD    1 
ATOM   5518 O OE1   . GLU A 1 770 ? 140.560 139.975 102.865 1.00 131.97 ? 770 GLU A OE1   1 
ATOM   5519 O OE2   . GLU A 1 770 ? 141.759 140.535 104.614 1.00 135.78 ? 770 GLU A OE2   1 
ATOM   5520 N N     . LEU A 1 771 ? 141.450 136.314 99.597  1.00 135.04 ? 771 LEU A N     1 
ATOM   5521 C CA    . LEU A 1 771 ? 141.374 135.201 98.656  1.00 134.94 ? 771 LEU A CA    1 
ATOM   5522 C C     . LEU A 1 771 ? 142.650 135.036 97.842  1.00 136.77 ? 771 LEU A C     1 
ATOM   5523 O O     . LEU A 1 771 ? 142.872 133.962 97.271  1.00 137.50 ? 771 LEU A O     1 
ATOM   5524 C CB    . LEU A 1 771 ? 140.190 135.395 97.709  1.00 134.10 ? 771 LEU A CB    1 
ATOM   5525 C CG    . LEU A 1 771 ? 138.816 135.602 98.346  1.00 136.23 ? 771 LEU A CG    1 
ATOM   5526 C CD1   . LEU A 1 771 ? 137.788 135.950 97.280  1.00 131.34 ? 771 LEU A CD1   1 
ATOM   5527 C CD2   . LEU A 1 771 ? 138.391 134.361 99.112  1.00 132.76 ? 771 LEU A CD2   1 
ATOM   5528 N N     . GLU A 1 772 ? 143.488 136.068 97.771  1.00 136.56 ? 772 GLU A N     1 
ATOM   5529 C CA    . GLU A 1 772 ? 144.627 136.083 96.864  1.00 132.57 ? 772 GLU A CA    1 
ATOM   5530 C C     . GLU A 1 772 ? 145.978 136.148 97.560  1.00 133.84 ? 772 GLU A C     1 
ATOM   5531 O O     . GLU A 1 772 ? 146.969 135.696 96.984  1.00 136.80 ? 772 GLU A O     1 
ATOM   5532 C CB    . GLU A 1 772 ? 144.505 137.270 95.892  1.00 132.85 ? 772 GLU A CB    1 
ATOM   5533 C CG    . GLU A 1 772 ? 145.390 137.180 94.658  1.00 138.85 ? 772 GLU A CG    1 
ATOM   5534 C CD    . GLU A 1 772 ? 146.665 137.989 94.791  1.00 142.14 ? 772 GLU A CD    1 
ATOM   5535 O OE1   . GLU A 1 772 ? 146.919 138.527 95.887  1.00 141.33 ? 772 GLU A OE1   1 
ATOM   5536 O OE2   . GLU A 1 772 ? 147.411 138.092 93.795  1.00 142.61 ? 772 GLU A OE2   1 
ATOM   5537 N N     . LEU A 1 773 ? 146.053 136.695 98.774  1.00 132.90 ? 773 LEU A N     1 
ATOM   5538 C CA    . LEU A 1 773 ? 147.339 136.780 99.456  1.00 136.84 ? 773 LEU A CA    1 
ATOM   5539 C C     . LEU A 1 773 ? 147.855 135.416 99.899  1.00 148.08 ? 773 LEU A C     1 
ATOM   5540 O O     . LEU A 1 773 ? 149.052 135.282 100.176 1.00 153.97 ? 773 LEU A O     1 
ATOM   5541 C CB    . LEU A 1 773 ? 147.243 137.732 100.653 1.00 136.55 ? 773 LEU A CB    1 
ATOM   5542 C CG    . LEU A 1 773 ? 146.052 137.635 101.612 1.00 134.73 ? 773 LEU A CG    1 
ATOM   5543 C CD1   . LEU A 1 773 ? 146.227 136.513 102.625 1.00 134.04 ? 773 LEU A CD1   1 
ATOM   5544 C CD2   . LEU A 1 773 ? 145.828 138.967 102.317 1.00 131.74 ? 773 LEU A CD2   1 
ATOM   5545 N N     . ASP A 1 774 ? 146.989 134.407 99.971  1.00 148.70 ? 774 ASP A N     1 
ATOM   5546 C CA    . ASP A 1 774 ? 147.404 133.063 100.353 1.00 147.38 ? 774 ASP A CA    1 
ATOM   5547 C C     . ASP A 1 774 ? 147.892 132.233 99.173  1.00 142.38 ? 774 ASP A C     1 
ATOM   5548 O O     . ASP A 1 774 ? 148.223 131.057 99.360  1.00 144.66 ? 774 ASP A O     1 
ATOM   5549 C CB    . ASP A 1 774 ? 146.254 132.335 101.053 1.00 149.27 ? 774 ASP A CB    1 
ATOM   5550 C CG    . ASP A 1 774 ? 146.036 132.820 102.471 1.00 150.14 ? 774 ASP A CG    1 
ATOM   5551 O OD1   . ASP A 1 774 ? 147.037 133.074 103.173 1.00 148.90 ? 774 ASP A OD1   1 
ATOM   5552 O OD2   . ASP A 1 774 ? 144.865 132.950 102.883 1.00 151.27 ? 774 ASP A OD2   1 
ATOM   5553 N N     . SER A 1 775 ? 147.943 132.807 97.979  1.00 141.22 ? 775 SER A N     1 
ATOM   5554 C CA    . SER A 1 775 ? 148.358 132.122 96.769  1.00 143.18 ? 775 SER A CA    1 
ATOM   5555 C C     . SER A 1 775 ? 149.673 132.710 96.275  1.00 142.48 ? 775 SER A C     1 
ATOM   5556 O O     . SER A 1 775 ? 150.029 133.839 96.634  1.00 144.05 ? 775 SER A O     1 
ATOM   5557 C CB    . SER A 1 775 ? 147.287 132.243 95.674  1.00 145.24 ? 775 SER A CB    1 
ATOM   5558 O OG    . SER A 1 775 ? 147.176 133.577 95.211  1.00 144.16 ? 775 SER A OG    1 
ATOM   5559 N N     . PRO A 1 776 ? 150.432 131.964 95.468  1.00 143.00 ? 776 PRO A N     1 
ATOM   5560 C CA    . PRO A 1 776 ? 151.717 132.493 94.983  1.00 145.36 ? 776 PRO A CA    1 
ATOM   5561 C C     . PRO A 1 776 ? 151.595 133.806 94.232  1.00 145.51 ? 776 PRO A C     1 
ATOM   5562 O O     . PRO A 1 776 ? 152.505 134.641 94.319  1.00 149.74 ? 776 PRO A O     1 
ATOM   5563 C CB    . PRO A 1 776 ? 152.233 131.369 94.075  1.00 146.85 ? 776 PRO A CB    1 
ATOM   5564 C CG    . PRO A 1 776 ? 151.606 130.133 94.625  1.00 147.88 ? 776 PRO A CG    1 
ATOM   5565 C CD    . PRO A 1 776 ? 150.244 130.548 95.100  1.00 145.79 ? 776 PRO A CD    1 
ATOM   5566 N N     . SER A 1 777 ? 150.496 134.017 93.503  1.00 142.73 ? 777 SER A N     1 
ATOM   5567 C CA    . SER A 1 777 ? 150.340 135.245 92.728  1.00 148.86 ? 777 SER A CA    1 
ATOM   5568 C C     . SER A 1 777 ? 150.400 136.484 93.611  1.00 149.88 ? 777 SER A C     1 
ATOM   5569 O O     . SER A 1 777 ? 150.900 137.529 93.179  1.00 148.22 ? 777 SER A O     1 
ATOM   5570 C CB    . SER A 1 777 ? 149.023 135.210 91.952  1.00 149.53 ? 777 SER A CB    1 
ATOM   5571 O OG    . SER A 1 777 ? 147.916 135.108 92.830  1.00 150.13 ? 777 SER A OG    1 
ATOM   5572 N N     . GLY A 1 778 ? 149.901 136.392 94.840  1.00 149.85 ? 778 GLY A N     1 
ATOM   5573 C CA    . GLY A 1 778 ? 149.946 137.515 95.754  1.00 150.65 ? 778 GLY A CA    1 
ATOM   5574 C C     . GLY A 1 778 ? 151.288 137.690 96.434  1.00 157.13 ? 778 GLY A C     1 
ATOM   5575 O O     . GLY A 1 778 ? 151.811 138.806 96.512  1.00 160.78 ? 778 GLY A O     1 
ATOM   5576 N N     . CYS A 1 779 ? 151.857 136.588 96.931  1.00 159.51 ? 779 CYS A N     1 
ATOM   5577 C CA    . CYS A 1 779 ? 153.125 136.677 97.646  1.00 162.77 ? 779 CYS A CA    1 
ATOM   5578 C C     . CYS A 1 779 ? 154.263 137.094 96.724  1.00 162.12 ? 779 CYS A C     1 
ATOM   5579 O O     . CYS A 1 779 ? 155.203 137.759 97.172  1.00 164.67 ? 779 CYS A O     1 
ATOM   5580 C CB    . CYS A 1 779 ? 153.448 135.345 98.326  1.00 166.38 ? 779 CYS A CB    1 
ATOM   5581 S SG    . CYS A 1 779 ? 154.012 134.038 97.215  1.00 175.29 ? 779 CYS A SG    1 
ATOM   5582 N N     . LYS A 1 780 ? 154.196 136.734 95.439  1.00 157.25 ? 780 LYS A N     1 
ATOM   5583 C CA    . LYS A 1 780 ? 155.242 137.145 94.507  1.00 158.52 ? 780 LYS A CA    1 
ATOM   5584 C C     . LYS A 1 780 ? 155.293 138.662 94.373  1.00 159.71 ? 780 LYS A C     1 
ATOM   5585 O O     . LYS A 1 780 ? 156.354 139.278 94.536  1.00 158.35 ? 780 LYS A O     1 
ATOM   5586 C CB    . LYS A 1 780 ? 155.020 136.488 93.143  1.00 156.07 ? 780 LYS A CB    1 
ATOM   5587 C CG    . LYS A 1 780 ? 155.386 135.013 93.092  1.00 159.08 ? 780 LYS A CG    1 
ATOM   5588 C CD    . LYS A 1 780 ? 156.875 134.802 93.306  1.00 165.27 ? 780 LYS A CD    1 
ATOM   5589 C CE    . LYS A 1 780 ? 157.243 133.330 93.218  1.00 170.39 ? 780 LYS A CE    1 
ATOM   5590 N NZ    . LYS A 1 780 ? 158.704 133.111 93.399  1.00 172.47 ? 780 LYS A NZ    1 
ATOM   5591 N N     . GLN A 1 781 ? 154.148 139.289 94.089  1.00 159.22 ? 781 GLN A N     1 
ATOM   5592 C CA    . GLN A 1 781 ? 154.126 140.742 93.967  1.00 157.95 ? 781 GLN A CA    1 
ATOM   5593 C C     . GLN A 1 781 ? 154.368 141.416 95.311  1.00 159.52 ? 781 GLN A C     1 
ATOM   5594 O O     . GLN A 1 781 ? 154.928 142.518 95.358  1.00 159.70 ? 781 GLN A O     1 
ATOM   5595 C CB    . GLN A 1 781 ? 152.803 141.204 93.351  1.00 154.61 ? 781 GLN A CB    1 
ATOM   5596 C CG    . GLN A 1 781 ? 151.561 140.888 94.170  1.00 157.55 ? 781 GLN A CG    1 
ATOM   5597 C CD    . GLN A 1 781 ? 151.205 141.994 95.146  1.00 157.60 ? 781 GLN A CD    1 
ATOM   5598 O OE1   . GLN A 1 781 ? 151.385 143.176 94.854  1.00 158.18 ? 781 GLN A OE1   1 
ATOM   5599 N NE2   . GLN A 1 781 ? 150.700 141.614 96.314  1.00 153.50 ? 781 GLN A NE2   1 
ATOM   5600 N N     . LEU A 1 782 ? 153.973 140.771 96.412  1.00 160.81 ? 782 LEU A N     1 
ATOM   5601 C CA    . LEU A 1 782 ? 154.291 141.308 97.730  1.00 158.21 ? 782 LEU A CA    1 
ATOM   5602 C C     . LEU A 1 782 ? 155.798 141.365 97.947  1.00 160.83 ? 782 LEU A C     1 
ATOM   5603 O O     . LEU A 1 782 ? 156.327 142.375 98.426  1.00 160.51 ? 782 LEU A O     1 
ATOM   5604 C CB    . LEU A 1 782 ? 153.615 140.461 98.809  1.00 155.08 ? 782 LEU A CB    1 
ATOM   5605 C CG    . LEU A 1 782 ? 153.699 140.943 100.256 1.00 148.76 ? 782 LEU A CG    1 
ATOM   5606 C CD1   . LEU A 1 782 ? 153.104 142.335 100.396 1.00 142.27 ? 782 LEU A CD1   1 
ATOM   5607 C CD2   . LEU A 1 782 ? 153.001 139.960 101.183 1.00 139.19 ? 782 LEU A CD2   1 
ATOM   5608 N N     . HIS A 1 783 ? 156.508 140.295 97.583  1.00 164.88 ? 783 HIS A N     1 
ATOM   5609 C CA    . HIS A 1 783 ? 157.965 140.295 97.676  1.00 168.81 ? 783 HIS A CA    1 
ATOM   5610 C C     . HIS A 1 783 ? 158.579 141.317 96.728  1.00 168.64 ? 783 HIS A C     1 
ATOM   5611 O O     . HIS A 1 783 ? 159.580 141.963 97.063  1.00 168.25 ? 783 HIS A O     1 
ATOM   5612 C CB    . HIS A 1 783 ? 158.506 138.896 97.386  1.00 170.04 ? 783 HIS A CB    1 
ATOM   5613 C CG    . HIS A 1 783 ? 159.998 138.833 97.289  1.00 173.72 ? 783 HIS A CG    1 
ATOM   5614 N ND1   . HIS A 1 783 ? 160.659 138.668 96.091  1.00 174.78 ? 783 HIS A ND1   1 
ATOM   5615 C CD2   . HIS A 1 783 ? 160.958 138.915 98.240  1.00 174.87 ? 783 HIS A CD2   1 
ATOM   5616 C CE1   . HIS A 1 783 ? 161.962 138.650 96.308  1.00 175.91 ? 783 HIS A CE1   1 
ATOM   5617 N NE2   . HIS A 1 783 ? 162.170 138.798 97.604  1.00 176.00 ? 783 HIS A NE2   1 
ATOM   5618 N N     . GLU A 1 784 ? 157.999 141.470 95.535  1.00 166.57 ? 784 GLU A N     1 
ATOM   5619 C CA    . GLU A 1 784 ? 158.492 142.481 94.604  1.00 165.60 ? 784 GLU A CA    1 
ATOM   5620 C C     . GLU A 1 784 ? 158.385 143.877 95.206  1.00 164.26 ? 784 GLU A C     1 
ATOM   5621 O O     . GLU A 1 784 ? 159.308 144.690 95.079  1.00 163.71 ? 784 GLU A O     1 
ATOM   5622 C CB    . GLU A 1 784 ? 157.720 142.406 93.286  1.00 166.18 ? 784 GLU A CB    1 
ATOM   5623 C CG    . GLU A 1 784 ? 157.946 141.126 92.494  1.00 166.45 ? 784 GLU A CG    1 
ATOM   5624 C CD    . GLU A 1 784 ? 159.327 141.054 91.870  1.00 170.36 ? 784 GLU A CD    1 
ATOM   5625 O OE1   . GLU A 1 784 ? 159.993 142.105 91.767  1.00 169.90 ? 784 GLU A OE1   1 
ATOM   5626 O OE2   . GLU A 1 784 ? 159.746 139.944 91.480  1.00 172.65 ? 784 GLU A OE2   1 
ATOM   5627 N N     . ASP A 1 785 ? 157.264 144.173 95.866  1.00 163.68 ? 785 ASP A N     1 
ATOM   5628 C CA    . ASP A 1 785 ? 157.112 145.468 96.524  1.00 161.93 ? 785 ASP A CA    1 
ATOM   5629 C C     . ASP A 1 785 ? 158.058 145.609 97.712  1.00 161.63 ? 785 ASP A C     1 
ATOM   5630 O O     . ASP A 1 785 ? 158.609 146.691 97.946  1.00 161.57 ? 785 ASP A O     1 
ATOM   5631 C CB    . ASP A 1 785 ? 155.662 145.666 96.964  1.00 155.86 ? 785 ASP A CB    1 
ATOM   5632 C CG    . ASP A 1 785 ? 154.742 145.997 95.806  1.00 153.97 ? 785 ASP A CG    1 
ATOM   5633 O OD1   . ASP A 1 785 ? 155.203 146.654 94.849  1.00 155.99 ? 785 ASP A OD1   1 
ATOM   5634 O OD2   . ASP A 1 785 ? 153.558 145.602 95.852  1.00 150.56 ? 785 ASP A OD2   1 
ATOM   5635 N N     . LEU A 1 786 ? 158.259 144.534 98.471  1.00 162.14 ? 786 LEU A N     1 
ATOM   5636 C CA    . LEU A 1 786 ? 159.043 144.582 99.700  1.00 159.93 ? 786 LEU A CA    1 
ATOM   5637 C C     . LEU A 1 786 ? 160.539 144.410 99.479  1.00 162.58 ? 786 LEU A C     1 
ATOM   5638 O O     . LEU A 1 786 ? 161.292 144.413 100.459 1.00 162.42 ? 786 LEU A O     1 
ATOM   5639 C CB    . LEU A 1 786 ? 158.558 143.507 100.672 1.00 156.58 ? 786 LEU A CB    1 
ATOM   5640 C CG    . LEU A 1 786 ? 157.151 143.673 101.235 1.00 154.39 ? 786 LEU A CG    1 
ATOM   5641 C CD1   . LEU A 1 786 ? 156.657 142.330 101.713 1.00 152.01 ? 786 LEU A CD1   1 
ATOM   5642 C CD2   . LEU A 1 786 ? 157.143 144.686 102.367 1.00 148.73 ? 786 LEU A CD2   1 
ATOM   5643 N N     . LYS A 1 787 ? 160.984 144.228 98.233  1.00 165.97 ? 787 LYS A N     1 
ATOM   5644 C CA    . LYS A 1 787 ? 162.415 144.070 97.980  1.00 164.09 ? 787 LYS A CA    1 
ATOM   5645 C C     . LYS A 1 787 ? 163.228 145.234 98.537  1.00 161.72 ? 787 LYS A C     1 
ATOM   5646 O O     . LYS A 1 787 ? 164.394 145.052 98.906  1.00 162.06 ? 787 LYS A O     1 
ATOM   5647 C CB    . LYS A 1 787 ? 162.675 143.916 96.480  1.00 160.08 ? 787 LYS A CB    1 
ATOM   5648 C CG    . LYS A 1 787 ? 162.442 145.178 95.665  1.00 156.73 ? 787 LYS A CG    1 
ATOM   5649 C CD    . LYS A 1 787 ? 163.152 145.111 94.321  1.00 153.38 ? 787 LYS A CD    1 
ATOM   5650 C CE    . LYS A 1 787 ? 162.517 144.084 93.399  1.00 152.18 ? 787 LYS A CE    1 
ATOM   5651 N NZ    . LYS A 1 787 ? 161.183 144.528 92.914  1.00 152.27 ? 787 LYS A NZ    1 
ATOM   5652 N N     . THR A 1 788 ? 162.643 146.429 98.606  1.00 159.53 ? 788 THR A N     1 
ATOM   5653 C CA    . THR A 1 788 ? 163.336 147.592 99.144  1.00 161.75 ? 788 THR A CA    1 
ATOM   5654 C C     . THR A 1 788 ? 163.192 147.733 100.654 1.00 161.58 ? 788 THR A C     1 
ATOM   5655 O O     . THR A 1 788 ? 163.888 148.562 101.251 1.00 162.41 ? 788 THR A O     1 
ATOM   5656 C CB    . THR A 1 788 ? 162.826 148.872 98.471  1.00 161.56 ? 788 THR A CB    1 
ATOM   5657 O OG1   . THR A 1 788 ? 161.428 149.032 98.740  1.00 158.31 ? 788 THR A OG1   1 
ATOM   5658 C CG2   . THR A 1 788 ? 163.043 148.803 96.967  1.00 158.37 ? 788 THR A CG2   1 
ATOM   5659 N N     . TRP A 1 789 ? 162.317 146.952 101.284 1.00 159.80 ? 789 TRP A N     1 
ATOM   5660 C CA    . TRP A 1 789 ? 162.061 147.069 102.714 1.00 159.97 ? 789 TRP A CA    1 
ATOM   5661 C C     . TRP A 1 789 ? 163.003 146.232 103.569 1.00 161.39 ? 789 TRP A C     1 
ATOM   5662 O O     . TRP A 1 789 ? 162.982 146.369 104.797 1.00 161.07 ? 789 TRP A O     1 
ATOM   5663 C CB    . TRP A 1 789 ? 160.611 146.679 103.020 1.00 158.63 ? 789 TRP A CB    1 
ATOM   5664 C CG    . TRP A 1 789 ? 159.612 147.679 102.524 1.00 158.67 ? 789 TRP A CG    1 
ATOM   5665 C CD1   . TRP A 1 789 ? 159.285 147.936 101.225 1.00 158.60 ? 789 TRP A CD1   1 
ATOM   5666 C CD2   . TRP A 1 789 ? 158.807 148.557 103.321 1.00 150.50 ? 789 TRP A CD2   1 
ATOM   5667 N NE1   . TRP A 1 789 ? 158.329 148.922 101.163 1.00 154.37 ? 789 TRP A NE1   1 
ATOM   5668 C CE2   . TRP A 1 789 ? 158.019 149.320 102.436 1.00 148.68 ? 789 TRP A CE2   1 
ATOM   5669 C CE3   . TRP A 1 789 ? 158.678 148.774 104.697 1.00 139.02 ? 789 TRP A CE3   1 
ATOM   5670 C CZ2   . TRP A 1 789 ? 157.115 150.281 102.882 1.00 139.96 ? 789 TRP A CZ2   1 
ATOM   5671 C CZ3   . TRP A 1 789 ? 157.782 149.728 105.137 1.00 132.25 ? 789 TRP A CZ3   1 
ATOM   5672 C CH2   . TRP A 1 789 ? 157.011 150.469 104.232 1.00 134.26 ? 789 TRP A CH2   1 
ATOM   5673 N N     . SER A 1 790 ? 163.824 145.375 102.962 1.00 162.76 ? 790 SER A N     1 
ATOM   5674 C CA    . SER A 1 790 ? 164.765 144.566 103.726 1.00 165.02 ? 790 SER A CA    1 
ATOM   5675 C C     . SER A 1 790 ? 166.063 145.299 104.040 1.00 167.00 ? 790 SER A C     1 
ATOM   5676 O O     . SER A 1 790 ? 166.864 144.792 104.834 1.00 165.58 ? 790 SER A O     1 
ATOM   5677 C CB    . SER A 1 790 ? 165.078 143.269 102.974 1.00 166.54 ? 790 SER A CB    1 
ATOM   5678 O OG    . SER A 1 790 ? 165.647 143.539 101.705 1.00 167.23 ? 790 SER A OG    1 
ATOM   5679 N N     . LYS A 1 791 ? 166.289 146.465 103.446 1.00 168.05 ? 791 LYS A N     1 
ATOM   5680 C CA    . LYS A 1 791 ? 167.486 147.250 103.704 1.00 166.81 ? 791 LYS A CA    1 
ATOM   5681 C C     . LYS A 1 791 ? 167.242 148.255 104.825 1.00 168.03 ? 791 LYS A C     1 
ATOM   5682 O O     . LYS A 1 791 ? 166.103 148.585 105.164 1.00 167.75 ? 791 LYS A O     1 
ATOM   5683 C CB    . LYS A 1 791 ? 167.940 147.978 102.437 1.00 163.67 ? 791 LYS A CB    1 
ATOM   5684 C CG    . LYS A 1 791 ? 169.079 147.296 101.693 1.00 163.82 ? 791 LYS A CG    1 
ATOM   5685 C CD    . LYS A 1 791 ? 168.677 145.924 101.175 1.00 168.11 ? 791 LYS A CD    1 
ATOM   5686 C CE    . LYS A 1 791 ? 167.579 146.025 100.130 1.00 169.05 ? 791 LYS A CE    1 
ATOM   5687 N NZ    . LYS A 1 791 ? 167.262 144.697 99.536  1.00 164.18 ? 791 LYS A NZ    1 
ATOM   5688 N N     . GLY A 1 792 ? 168.338 148.740 105.402 1.00 169.70 ? 792 GLY A N     1 
ATOM   5689 C CA    . GLY A 1 792 ? 168.277 149.742 106.439 1.00 170.61 ? 792 GLY A CA    1 
ATOM   5690 C C     . GLY A 1 792 ? 168.086 149.157 107.823 1.00 170.41 ? 792 GLY A C     1 
ATOM   5691 O O     . GLY A 1 792 ? 168.034 147.936 108.008 1.00 168.52 ? 792 GLY A O     1 
ATOM   5692 N N     . PRO A 1 793 ? 167.983 150.028 108.829 1.00 171.59 ? 793 PRO A N     1 
ATOM   5693 C CA    . PRO A 1 793 ? 167.821 149.543 110.197 1.00 168.05 ? 793 PRO A CA    1 
ATOM   5694 C C     . PRO A 1 793 ? 166.467 148.891 110.386 1.00 164.48 ? 793 PRO A C     1 
ATOM   5695 O O     . PRO A 1 793 ? 165.491 149.236 109.695 1.00 164.15 ? 793 PRO A O     1 
ATOM   5696 C CB    . PRO A 1 793 ? 167.952 150.824 111.043 1.00 165.70 ? 793 PRO A CB    1 
ATOM   5697 C CG    . PRO A 1 793 ? 167.540 151.918 110.120 1.00 162.74 ? 793 PRO A CG    1 
ATOM   5698 C CD    . PRO A 1 793 ? 168.015 151.499 108.757 1.00 167.76 ? 793 PRO A CD    1 
ATOM   5699 N N     . PRO A 1 794 ? 166.352 147.938 111.308 1.00 163.07 ? 794 PRO A N     1 
ATOM   5700 C CA    . PRO A 1 794 ? 165.061 147.288 111.546 1.00 163.23 ? 794 PRO A CA    1 
ATOM   5701 C C     . PRO A 1 794 ? 164.068 148.231 112.209 1.00 162.53 ? 794 PRO A C     1 
ATOM   5702 O O     . PRO A 1 794 ? 164.431 149.194 112.888 1.00 161.31 ? 794 PRO A O     1 
ATOM   5703 C CB    . PRO A 1 794 ? 165.418 146.120 112.471 1.00 161.43 ? 794 PRO A CB    1 
ATOM   5704 C CG    . PRO A 1 794 ? 166.650 146.576 113.179 1.00 163.08 ? 794 PRO A CG    1 
ATOM   5705 C CD    . PRO A 1 794 ? 167.414 147.398 112.176 1.00 162.82 ? 794 PRO A CD    1 
ATOM   5706 N N     . LEU A 1 795 ? 162.788 147.936 111.994 1.00 161.72 ? 795 LEU A N     1 
ATOM   5707 C CA    . LEU A 1 795 ? 161.724 148.718 112.607 1.00 157.54 ? 795 LEU A CA    1 
ATOM   5708 C C     . LEU A 1 795 ? 161.699 148.496 114.115 1.00 154.79 ? 795 LEU A C     1 
ATOM   5709 O O     . LEU A 1 795 ? 161.886 147.376 114.598 1.00 155.11 ? 795 LEU A O     1 
ATOM   5710 C CB    . LEU A 1 795 ? 160.372 148.346 111.998 1.00 155.94 ? 795 LEU A CB    1 
ATOM   5711 C CG    . LEU A 1 795 ? 160.233 148.532 110.485 1.00 154.37 ? 795 LEU A CG    1 
ATOM   5712 C CD1   . LEU A 1 795 ? 158.839 148.138 110.020 1.00 149.32 ? 795 LEU A CD1   1 
ATOM   5713 C CD2   . LEU A 1 795 ? 160.550 149.966 110.088 1.00 148.85 ? 795 LEU A CD2   1 
ATOM   5714 N N     . LYS A 1 796 ? 161.468 149.574 114.860 1.00 151.08 ? 796 LYS A N     1 
ATOM   5715 C CA    . LYS A 1 796 ? 161.448 149.504 116.315 1.00 147.10 ? 796 LYS A CA    1 
ATOM   5716 C C     . LYS A 1 796 ? 160.027 149.259 116.805 1.00 141.58 ? 796 LYS A C     1 
ATOM   5717 O O     . LYS A 1 796 ? 159.148 150.094 116.557 1.00 141.37 ? 796 LYS A O     1 
ATOM   5718 C CB    . LYS A 1 796 ? 161.987 150.789 116.922 1.00 148.13 ? 796 LYS A CB    1 
ATOM   5719 C CG    . LYS A 1 796 ? 161.926 150.826 118.441 1.00 147.71 ? 796 LYS A CG    1 
ATOM   5720 C CD    . LYS A 1 796 ? 162.289 152.201 118.977 1.00 146.51 ? 796 LYS A CD    1 
ATOM   5721 C CE    . LYS A 1 796 ? 163.701 152.598 118.578 1.00 146.82 ? 796 LYS A CE    1 
ATOM   5722 N NZ    . LYS A 1 796 ? 164.058 153.953 119.083 1.00 147.29 ? 796 LYS A NZ    1 
ATOM   5723 N N     . PRO A 1 797 ? 159.756 148.146 117.485 1.00 139.84 ? 797 PRO A N     1 
ATOM   5724 C CA    . PRO A 1 797 ? 158.429 147.952 118.080 1.00 140.81 ? 797 PRO A CA    1 
ATOM   5725 C C     . PRO A 1 797 ? 158.149 148.995 119.154 1.00 137.71 ? 797 PRO A C     1 
ATOM   5726 O O     . PRO A 1 797 ? 159.044 149.408 119.894 1.00 140.12 ? 797 PRO A O     1 
ATOM   5727 C CB    . PRO A 1 797 ? 158.507 146.540 118.672 1.00 144.93 ? 797 PRO A CB    1 
ATOM   5728 C CG    . PRO A 1 797 ? 159.629 145.874 117.938 1.00 146.21 ? 797 PRO A CG    1 
ATOM   5729 C CD    . PRO A 1 797 ? 160.616 146.962 117.650 1.00 143.90 ? 797 PRO A CD    1 
ATOM   5730 N N     . LEU A 1 798 ? 156.892 149.418 119.233 1.00 137.27 ? 798 LEU A N     1 
ATOM   5731 C CA    . LEU A 1 798 ? 156.448 150.420 120.200 1.00 137.10 ? 798 LEU A CA    1 
ATOM   5732 C C     . LEU A 1 798 ? 155.514 149.740 121.199 1.00 138.36 ? 798 LEU A C     1 
ATOM   5733 O O     . LEU A 1 798 ? 154.306 149.640 120.975 1.00 138.84 ? 798 LEU A O     1 
ATOM   5734 C CB    . LEU A 1 798 ? 155.763 151.592 119.500 1.00 134.36 ? 798 LEU A CB    1 
ATOM   5735 C CG    . LEU A 1 798 ? 156.624 152.373 118.507 1.00 129.64 ? 798 LEU A CG    1 
ATOM   5736 C CD1   . LEU A 1 798 ? 155.859 153.562 117.962 1.00 124.31 ? 798 LEU A CD1   1 
ATOM   5737 C CD2   . LEU A 1 798 ? 157.924 152.820 119.158 1.00 131.95 ? 798 LEU A CD2   1 
ATOM   5738 N N     . THR A 1 799 ? 156.084 149.274 122.307 1.00 139.54 ? 799 THR A N     1 
ATOM   5739 C CA    . THR A 1 799 ? 155.286 148.660 123.358 1.00 139.26 ? 799 THR A CA    1 
ATOM   5740 C C     . THR A 1 799 ? 154.350 149.690 123.979 1.00 142.15 ? 799 THR A C     1 
ATOM   5741 O O     . THR A 1 799 ? 154.750 150.818 124.277 1.00 144.32 ? 799 THR A O     1 
ATOM   5742 C CB    . THR A 1 799 ? 156.193 148.056 124.431 1.00 137.28 ? 799 THR A CB    1 
ATOM   5743 O OG1   . THR A 1 799 ? 157.086 147.112 123.827 1.00 134.21 ? 799 THR A OG1   1 
ATOM   5744 C CG2   . THR A 1 799 ? 155.368 147.350 125.498 1.00 133.34 ? 799 THR A CG2   1 
ATOM   5745 N N     . PHE A 1 800 ? 153.095 149.296 124.169 1.00 144.12 ? 800 PHE A N     1 
ATOM   5746 C CA    . PHE A 1 800 ? 152.086 150.192 124.723 1.00 147.73 ? 800 PHE A CA    1 
ATOM   5747 C C     . PHE A 1 800 ? 152.391 150.523 126.181 1.00 149.98 ? 800 PHE A C     1 
ATOM   5748 O O     . PHE A 1 800 ? 152.550 149.627 127.010 1.00 147.70 ? 800 PHE A O     1 
ATOM   5749 C CB    . PHE A 1 800 ? 150.693 149.571 124.601 1.00 148.40 ? 800 PHE A CB    1 
ATOM   5750 C CG    . PHE A 1 800 ? 149.572 150.539 124.858 1.00 149.41 ? 800 PHE A CG    1 
ATOM   5751 C CD1   . PHE A 1 800 ? 149.065 150.712 126.136 1.00 151.61 ? 800 PHE A CD1   1 
ATOM   5752 C CD2   . PHE A 1 800 ? 149.025 151.275 123.820 1.00 148.24 ? 800 PHE A CD2   1 
ATOM   5753 C CE1   . PHE A 1 800 ? 148.034 151.602 126.373 1.00 152.08 ? 800 PHE A CE1   1 
ATOM   5754 C CE2   . PHE A 1 800 ? 147.994 152.166 124.051 1.00 149.91 ? 800 PHE A CE2   1 
ATOM   5755 C CZ    . PHE A 1 800 ? 147.498 152.329 125.329 1.00 151.53 ? 800 PHE A CZ    1 
ATOM   5756 N N     . ASN A 1 807 ? 154.149 160.340 122.970 1.00 143.23 ? 807 ASN A N     1 
ATOM   5757 C CA    . ASN A 1 807 ? 154.299 158.949 122.561 1.00 143.57 ? 807 ASN A CA    1 
ATOM   5758 C C     . ASN A 1 807 ? 153.108 158.492 121.726 1.00 142.47 ? 807 ASN A C     1 
ATOM   5759 O O     . ASN A 1 807 ? 153.216 157.550 120.942 1.00 141.81 ? 807 ASN A O     1 
ATOM   5760 C CB    . ASN A 1 807 ? 154.468 158.047 123.785 1.00 148.25 ? 807 ASN A CB    1 
ATOM   5761 C CG    . ASN A 1 807 ? 153.374 158.251 124.815 1.00 147.93 ? 807 ASN A CG    1 
ATOM   5762 O OD1   . ASN A 1 807 ? 152.276 157.710 124.689 1.00 148.64 ? 807 ASN A OD1   1 
ATOM   5763 N ND2   . ASN A 1 807 ? 153.673 159.033 125.847 1.00 144.74 ? 807 ASN A ND2   1 
ATOM   5764 N N     . PHE A 1 808 ? 151.970 159.162 121.917 1.00 143.15 ? 808 PHE A N     1 
ATOM   5765 C CA    . PHE A 1 808 ? 150.752 158.946 121.137 1.00 143.39 ? 808 PHE A CA    1 
ATOM   5766 C C     . PHE A 1 808 ? 150.201 157.531 121.277 1.00 143.74 ? 808 PHE A C     1 
ATOM   5767 O O     . PHE A 1 808 ? 149.437 157.075 120.420 1.00 144.65 ? 808 PHE A O     1 
ATOM   5768 C CB    . PHE A 1 808 ? 150.972 159.276 119.656 1.00 142.49 ? 808 PHE A CB    1 
ATOM   5769 C CG    . PHE A 1 808 ? 151.185 160.737 119.385 1.00 141.36 ? 808 PHE A CG    1 
ATOM   5770 C CD1   . PHE A 1 808 ? 152.453 161.288 119.439 1.00 140.33 ? 808 PHE A CD1   1 
ATOM   5771 C CD2   . PHE A 1 808 ? 150.114 161.559 119.075 1.00 140.39 ? 808 PHE A CD2   1 
ATOM   5772 C CE1   . PHE A 1 808 ? 152.651 162.633 119.189 1.00 139.59 ? 808 PHE A CE1   1 
ATOM   5773 C CE2   . PHE A 1 808 ? 150.305 162.904 118.824 1.00 137.86 ? 808 PHE A CE2   1 
ATOM   5774 C CZ    . PHE A 1 808 ? 151.575 163.442 118.881 1.00 138.18 ? 808 PHE A CZ    1 
ATOM   5775 N N     . HIS A 1 809 ? 150.576 156.814 122.338 1.00 143.00 ? 809 HIS A N     1 
ATOM   5776 C CA    . HIS A 1 809 ? 150.022 155.482 122.556 1.00 147.32 ? 809 HIS A CA    1 
ATOM   5777 C C     . HIS A 1 809 ? 148.523 155.548 122.828 1.00 149.98 ? 809 HIS A C     1 
ATOM   5778 O O     . HIS A 1 809 ? 147.734 154.823 122.212 1.00 149.94 ? 809 HIS A O     1 
ATOM   5779 C CB    . HIS A 1 809 ? 150.745 154.790 123.713 1.00 148.26 ? 809 HIS A CB    1 
ATOM   5780 C CG    . HIS A 1 809 ? 152.184 154.487 123.435 1.00 146.52 ? 809 HIS A CG    1 
ATOM   5781 N ND1   . HIS A 1 809 ? 152.590 153.711 122.371 1.00 144.72 ? 809 HIS A ND1   1 
ATOM   5782 C CD2   . HIS A 1 809 ? 153.313 154.844 124.092 1.00 147.42 ? 809 HIS A CD2   1 
ATOM   5783 C CE1   . HIS A 1 809 ? 153.907 153.610 122.379 1.00 145.14 ? 809 HIS A CE1   1 
ATOM   5784 N NE2   . HIS A 1 809 ? 154.371 154.289 123.413 1.00 147.64 ? 809 HIS A NE2   1 
ATOM   5785 N N     . VAL A 1 810 ? 148.114 156.416 123.755 1.00 149.32 ? 810 VAL A N     1 
ATOM   5786 C CA    . VAL A 1 810 ? 146.711 156.477 124.154 1.00 149.89 ? 810 VAL A CA    1 
ATOM   5787 C C     . VAL A 1 810 ? 145.862 157.138 123.073 1.00 151.34 ? 810 VAL A C     1 
ATOM   5788 O O     . VAL A 1 810 ? 144.698 156.773 122.873 1.00 151.77 ? 810 VAL A O     1 
ATOM   5789 C CB    . VAL A 1 810 ? 146.575 157.204 125.504 1.00 149.77 ? 810 VAL A CB    1 
ATOM   5790 C CG1   . VAL A 1 810 ? 145.146 157.113 126.014 1.00 151.12 ? 810 VAL A CG1   1 
ATOM   5791 C CG2   . VAL A 1 810 ? 147.549 156.624 126.518 1.00 147.66 ? 810 VAL A CG2   1 
ATOM   5792 N N     . ASP A 1 811 ? 146.417 158.136 122.380 1.00 151.95 ? 811 ASP A N     1 
ATOM   5793 C CA    . ASP A 1 811 ? 145.629 158.896 121.412 1.00 151.73 ? 811 ASP A CA    1 
ATOM   5794 C C     . ASP A 1 811 ? 145.139 158.010 120.272 1.00 149.54 ? 811 ASP A C     1 
ATOM   5795 O O     . ASP A 1 811 ? 143.991 158.135 119.828 1.00 148.30 ? 811 ASP A O     1 
ATOM   5796 C CB    . ASP A 1 811 ? 146.454 160.062 120.866 1.00 149.27 ? 811 ASP A CB    1 
ATOM   5797 C CG    . ASP A 1 811 ? 146.925 161.004 121.957 1.00 147.93 ? 811 ASP A CG    1 
ATOM   5798 O OD1   . ASP A 1 811 ? 147.874 160.648 122.687 1.00 143.31 ? 811 ASP A OD1   1 
ATOM   5799 O OD2   . ASP A 1 811 ? 146.346 162.104 122.084 1.00 151.92 ? 811 ASP A OD2   1 
ATOM   5800 N N     . PHE A 1 812 ? 145.999 157.113 119.786 1.00 148.74 ? 812 PHE A N     1 
ATOM   5801 C CA    . PHE A 1 812 ? 145.628 156.233 118.683 1.00 146.33 ? 812 PHE A CA    1 
ATOM   5802 C C     . PHE A 1 812 ? 144.436 155.360 119.053 1.00 145.26 ? 812 PHE A C     1 
ATOM   5803 O O     . PHE A 1 812 ? 143.440 155.298 118.318 1.00 142.49 ? 812 PHE A O     1 
ATOM   5804 C CB    . PHE A 1 812 ? 146.835 155.377 118.292 1.00 145.15 ? 812 PHE A CB    1 
ATOM   5805 C CG    . PHE A 1 812 ? 146.547 154.349 117.235 1.00 140.92 ? 812 PHE A CG    1 
ATOM   5806 C CD1   . PHE A 1 812 ? 146.617 154.679 115.892 1.00 135.20 ? 812 PHE A CD1   1 
ATOM   5807 C CD2   . PHE A 1 812 ? 146.233 153.046 117.584 1.00 138.36 ? 812 PHE A CD2   1 
ATOM   5808 C CE1   . PHE A 1 812 ? 146.362 153.733 114.919 1.00 127.74 ? 812 PHE A CE1   1 
ATOM   5809 C CE2   . PHE A 1 812 ? 145.976 152.097 116.615 1.00 133.81 ? 812 PHE A CE2   1 
ATOM   5810 C CZ    . PHE A 1 812 ? 146.041 152.442 115.281 1.00 126.45 ? 812 PHE A CZ    1 
ATOM   5811 N N     . VAL A 1 813 ? 144.518 154.681 120.200 1.00 147.13 ? 813 VAL A N     1 
ATOM   5812 C CA    . VAL A 1 813 ? 143.442 153.784 120.602 1.00 148.89 ? 813 VAL A CA    1 
ATOM   5813 C C     . VAL A 1 813 ? 142.180 154.572 120.930 1.00 150.95 ? 813 VAL A C     1 
ATOM   5814 O O     . VAL A 1 813 ? 141.067 154.112 120.660 1.00 152.66 ? 813 VAL A O     1 
ATOM   5815 C CB    . VAL A 1 813 ? 143.884 152.884 121.773 1.00 149.97 ? 813 VAL A CB    1 
ATOM   5816 C CG1   . VAL A 1 813 ? 144.995 151.945 121.326 1.00 146.57 ? 813 VAL A CG1   1 
ATOM   5817 C CG2   . VAL A 1 813 ? 144.331 153.709 122.965 1.00 152.37 ? 813 VAL A CG2   1 
ATOM   5818 N N     . VAL A 1 814 ? 142.324 155.772 121.502 1.00 153.05 ? 814 VAL A N     1 
ATOM   5819 C CA    . VAL A 1 814 ? 141.148 156.586 121.808 1.00 156.35 ? 814 VAL A CA    1 
ATOM   5820 C C     . VAL A 1 814 ? 140.425 156.980 120.526 1.00 154.27 ? 814 VAL A C     1 
ATOM   5821 O O     . VAL A 1 814 ? 139.196 156.870 120.426 1.00 153.50 ? 814 VAL A O     1 
ATOM   5822 C CB    . VAL A 1 814 ? 141.547 157.821 122.637 1.00 155.73 ? 814 VAL A CB    1 
ATOM   5823 C CG1   . VAL A 1 814 ? 140.445 158.869 122.595 1.00 152.46 ? 814 VAL A CG1   1 
ATOM   5824 C CG2   . VAL A 1 814 ? 141.833 157.420 124.076 1.00 155.80 ? 814 VAL A CG2   1 
ATOM   5825 N N     . ALA A 1 815 ? 141.177 157.442 119.523 1.00 151.83 ? 815 ALA A N     1 
ATOM   5826 C CA    . ALA A 1 815 ? 140.562 157.830 118.258 1.00 147.47 ? 815 ALA A CA    1 
ATOM   5827 C C     . ALA A 1 815 ? 139.915 156.636 117.568 1.00 145.44 ? 815 ALA A C     1 
ATOM   5828 O O     . ALA A 1 815 ? 138.796 156.740 117.049 1.00 144.98 ? 815 ALA A O     1 
ATOM   5829 C CB    . ALA A 1 815 ? 141.602 158.481 117.346 1.00 144.00 ? 815 ALA A CB    1 
ATOM   5830 N N     . ALA A 1 816 ? 140.602 155.489 117.559 1.00 144.24 ? 816 ALA A N     1 
ATOM   5831 C CA    . ALA A 1 816 ? 140.032 154.299 116.937 1.00 143.02 ? 816 ALA A CA    1 
ATOM   5832 C C     . ALA A 1 816 ? 138.757 153.858 117.647 1.00 146.49 ? 816 ALA A C     1 
ATOM   5833 O O     . ALA A 1 816 ? 137.766 153.504 116.996 1.00 143.64 ? 816 ALA A O     1 
ATOM   5834 C CB    . ALA A 1 816 ? 141.061 153.169 116.926 1.00 140.29 ? 816 ALA A CB    1 
ATOM   5835 N N     . ALA A 1 817 ? 138.763 153.876 118.982 1.00 150.54 ? 817 ALA A N     1 
ATOM   5836 C CA    . ALA A 1 817 ? 137.582 153.478 119.738 1.00 153.31 ? 817 ALA A CA    1 
ATOM   5837 C C     . ALA A 1 817 ? 136.423 154.430 119.490 1.00 153.87 ? 817 ALA A C     1 
ATOM   5838 O O     . ALA A 1 817 ? 135.278 153.993 119.337 1.00 152.31 ? 817 ALA A O     1 
ATOM   5839 C CB    . ALA A 1 817 ? 137.911 153.408 121.229 1.00 153.37 ? 817 ALA A CB    1 
ATOM   5840 N N     . SER A 1 818 ? 136.697 155.737 119.445 1.00 154.36 ? 818 SER A N     1 
ATOM   5841 C CA    . SER A 1 818 ? 135.635 156.700 119.171 1.00 153.36 ? 818 SER A CA    1 
ATOM   5842 C C     . SER A 1 818 ? 135.044 156.487 117.783 1.00 151.60 ? 818 SER A C     1 
ATOM   5843 O O     . SER A 1 818 ? 133.816 156.492 117.613 1.00 151.87 ? 818 SER A O     1 
ATOM   5844 C CB    . SER A 1 818 ? 136.168 158.125 119.316 1.00 154.59 ? 818 SER A CB    1 
ATOM   5845 O OG    . SER A 1 818 ? 136.631 158.366 120.633 1.00 155.82 ? 818 SER A OG    1 
ATOM   5846 N N     . LEU A 1 819 ? 135.902 156.285 116.778 1.00 148.20 ? 819 LEU A N     1 
ATOM   5847 C CA    . LEU A 1 819 ? 135.411 156.066 115.421 1.00 141.38 ? 819 LEU A CA    1 
ATOM   5848 C C     . LEU A 1 819 ? 134.574 154.796 115.337 1.00 144.00 ? 819 LEU A C     1 
ATOM   5849 O O     . LEU A 1 819 ? 133.487 154.794 114.750 1.00 145.28 ? 819 LEU A O     1 
ATOM   5850 C CB    . LEU A 1 819 ? 136.583 156.006 114.440 1.00 134.46 ? 819 LEU A CB    1 
ATOM   5851 C CG    . LEU A 1 819 ? 137.336 157.315 114.195 1.00 135.88 ? 819 LEU A CG    1 
ATOM   5852 C CD1   . LEU A 1 819 ? 138.556 157.073 113.322 1.00 126.15 ? 819 LEU A CD1   1 
ATOM   5853 C CD2   . LEU A 1 819 ? 136.419 158.351 113.564 1.00 130.78 ? 819 LEU A CD2   1 
ATOM   5854 N N     . ARG A 1 820 ? 135.056 153.706 115.939 1.00 144.51 ? 820 ARG A N     1 
ATOM   5855 C CA    . ARG A 1 820 ? 134.315 152.448 115.894 1.00 146.92 ? 820 ARG A CA    1 
ATOM   5856 C C     . ARG A 1 820 ? 132.991 152.557 116.642 1.00 146.54 ? 820 ARG A C     1 
ATOM   5857 O O     . ARG A 1 820 ? 131.968 152.023 116.194 1.00 143.42 ? 820 ARG A O     1 
ATOM   5858 C CB    . ARG A 1 820 ? 135.170 151.319 116.471 1.00 145.67 ? 820 ARG A CB    1 
ATOM   5859 C CG    . ARG A 1 820 ? 134.720 149.919 116.080 1.00 142.38 ? 820 ARG A CG    1 
ATOM   5860 C CD    . ARG A 1 820 ? 134.983 149.638 114.608 1.00 139.02 ? 820 ARG A CD    1 
ATOM   5861 N NE    . ARG A 1 820 ? 134.828 148.224 114.287 1.00 136.11 ? 820 ARG A NE    1 
ATOM   5862 C CZ    . ARG A 1 820 ? 135.056 147.697 113.092 1.00 130.01 ? 820 ARG A CZ    1 
ATOM   5863 N NH1   . ARG A 1 820 ? 135.446 148.441 112.070 1.00 126.46 ? 820 ARG A NH1   1 
ATOM   5864 N NH2   . ARG A 1 820 ? 134.890 146.389 112.917 1.00 127.24 ? 820 ARG A NH2   1 
ATOM   5865 N N     . ALA A 1 821 ? 132.991 153.240 117.791 1.00 148.19 ? 821 ALA A N     1 
ATOM   5866 C CA    . ALA A 1 821 ? 131.774 153.382 118.581 1.00 149.01 ? 821 ALA A CA    1 
ATOM   5867 C C     . ALA A 1 821 ? 130.731 154.215 117.850 1.00 150.78 ? 821 ALA A C     1 
ATOM   5868 O O     . ALA A 1 821 ? 129.538 153.893 117.887 1.00 150.61 ? 821 ALA A O     1 
ATOM   5869 C CB    . ALA A 1 821 ? 132.100 154.000 119.940 1.00 150.03 ? 821 ALA A CB    1 
ATOM   5870 N N     . GLN A 1 822 ? 131.153 155.297 117.192 1.00 151.94 ? 822 GLN A N     1 
ATOM   5871 C CA    . GLN A 1 822 ? 130.200 156.058 116.392 1.00 152.86 ? 822 GLN A CA    1 
ATOM   5872 C C     . GLN A 1 822 ? 129.780 155.290 115.145 1.00 149.51 ? 822 GLN A C     1 
ATOM   5873 O O     . GLN A 1 822 ? 128.685 155.518 114.619 1.00 152.88 ? 822 GLN A O     1 
ATOM   5874 C CB    . GLN A 1 822 ? 130.785 157.418 116.014 1.00 152.88 ? 822 GLN A CB    1 
ATOM   5875 C CG    . GLN A 1 822 ? 130.923 158.374 117.188 1.00 155.00 ? 822 GLN A CG    1 
ATOM   5876 C CD    . GLN A 1 822 ? 131.185 159.800 116.749 1.00 155.82 ? 822 GLN A CD    1 
ATOM   5877 O OE1   . GLN A 1 822 ? 131.264 160.089 115.555 1.00 155.75 ? 822 GLN A OE1   1 
ATOM   5878 N NE2   . GLN A 1 822 ? 131.319 160.701 117.714 1.00 154.49 ? 822 GLN A NE2   1 
ATOM   5879 N N     . ASN A 1 823 ? 130.632 154.384 114.659 1.00 143.60 ? 823 ASN A N     1 
ATOM   5880 C CA    . ASN A 1 823 ? 130.274 153.577 113.498 1.00 138.96 ? 823 ASN A CA    1 
ATOM   5881 C C     . ASN A 1 823 ? 129.175 152.576 113.838 1.00 142.67 ? 823 ASN A C     1 
ATOM   5882 O O     . ASN A 1 823 ? 128.175 152.470 113.119 1.00 142.01 ? 823 ASN A O     1 
ATOM   5883 C CB    . ASN A 1 823 ? 131.515 152.861 112.964 1.00 133.53 ? 823 ASN A CB    1 
ATOM   5884 C CG    . ASN A 1 823 ? 131.328 152.332 111.555 1.00 128.11 ? 823 ASN A CG    1 
ATOM   5885 O OD1   . ASN A 1 823 ? 130.233 151.924 111.168 1.00 128.72 ? 823 ASN A OD1   1 
ATOM   5886 N ND2   . ASN A 1 823 ? 132.403 152.337 110.776 1.00 119.34 ? 823 ASN A ND2   1 
ATOM   5887 N N     . TYR A 1 824 ? 129.339 151.835 114.932 1.00 143.74 ? 824 TYR A N     1 
ATOM   5888 C CA    . TYR A 1 824 ? 128.401 150.779 115.292 1.00 141.74 ? 824 TYR A CA    1 
ATOM   5889 C C     . TYR A 1 824 ? 127.386 151.203 116.345 1.00 139.83 ? 824 TYR A C     1 
ATOM   5890 O O     . TYR A 1 824 ? 126.621 150.360 116.822 1.00 137.16 ? 824 TYR A O     1 
ATOM   5891 C CB    . TYR A 1 824 ? 129.162 149.535 115.763 1.00 141.27 ? 824 TYR A CB    1 
ATOM   5892 C CG    . TYR A 1 824 ? 129.738 148.726 114.620 1.00 137.44 ? 824 TYR A CG    1 
ATOM   5893 C CD1   . TYR A 1 824 ? 131.008 148.989 114.126 1.00 136.66 ? 824 TYR A CD1   1 
ATOM   5894 C CD2   . TYR A 1 824 ? 129.003 147.708 114.026 1.00 131.49 ? 824 TYR A CD2   1 
ATOM   5895 C CE1   . TYR A 1 824 ? 131.533 148.256 113.077 1.00 130.59 ? 824 TYR A CE1   1 
ATOM   5896 C CE2   . TYR A 1 824 ? 129.520 146.969 112.977 1.00 125.97 ? 824 TYR A CE2   1 
ATOM   5897 C CZ    . TYR A 1 824 ? 130.784 147.247 112.507 1.00 123.37 ? 824 TYR A CZ    1 
ATOM   5898 O OH    . TYR A 1 824 ? 131.302 146.516 111.464 1.00 115.26 ? 824 TYR A OH    1 
ATOM   5899 N N     . GLY A 1 825 ? 127.363 152.477 116.725 1.00 141.14 ? 825 GLY A N     1 
ATOM   5900 C CA    . GLY A 1 825 ? 126.326 152.995 117.591 1.00 144.21 ? 825 GLY A CA    1 
ATOM   5901 C C     . GLY A 1 825 ? 126.460 152.650 119.057 1.00 150.04 ? 825 GLY A C     1 
ATOM   5902 O O     . GLY A 1 825 ? 125.574 153.011 119.840 1.00 152.68 ? 825 GLY A O     1 
ATOM   5903 N N     . ILE A 1 826 ? 127.524 151.961 119.456 1.00 150.22 ? 826 ILE A N     1 
ATOM   5904 C CA    . ILE A 1 826 ? 127.762 151.645 120.862 1.00 151.41 ? 826 ILE A CA    1 
ATOM   5905 C C     . ILE A 1 826 ? 128.254 152.913 121.552 1.00 154.02 ? 826 ILE A C     1 
ATOM   5906 O O     . ILE A 1 826 ? 128.701 153.845 120.867 1.00 152.06 ? 826 ILE A O     1 
ATOM   5907 C CB    . ILE A 1 826 ? 128.760 150.484 121.008 1.00 149.55 ? 826 ILE A CB    1 
ATOM   5908 C CG1   . ILE A 1 826 ? 130.116 150.867 120.423 1.00 154.57 ? 826 ILE A CG1   1 
ATOM   5909 C CG2   . ILE A 1 826 ? 128.221 149.233 120.333 1.00 142.83 ? 826 ILE A CG2   1 
ATOM   5910 C CD1   . ILE A 1 826 ? 131.263 150.686 121.385 1.00 156.25 ? 826 ILE A CD1   1 
ATOM   5911 N N     . PRO A 1 827 ? 128.177 153.014 122.882 1.00 157.27 ? 827 PRO A N     1 
ATOM   5912 C CA    . PRO A 1 827 ? 128.628 154.244 123.546 1.00 157.98 ? 827 PRO A CA    1 
ATOM   5913 C C     . PRO A 1 827 ? 130.120 154.473 123.355 1.00 157.07 ? 827 PRO A C     1 
ATOM   5914 O O     . PRO A 1 827 ? 130.912 153.532 123.267 1.00 157.87 ? 827 PRO A O     1 
ATOM   5915 C CB    . PRO A 1 827 ? 128.282 154.000 125.019 1.00 159.05 ? 827 PRO A CB    1 
ATOM   5916 C CG    . PRO A 1 827 ? 128.235 152.519 125.154 1.00 158.78 ? 827 PRO A CG    1 
ATOM   5917 C CD    . PRO A 1 827 ? 127.682 152.022 123.853 1.00 157.58 ? 827 PRO A CD    1 
ATOM   5918 N N     . VAL A 1 828 ? 130.495 155.746 123.290 1.00 157.81 ? 828 VAL A N     1 
ATOM   5919 C CA    . VAL A 1 828 ? 131.885 156.143 123.092 1.00 160.02 ? 828 VAL A CA    1 
ATOM   5920 C C     . VAL A 1 828 ? 132.576 156.184 124.449 1.00 162.12 ? 828 VAL A C     1 
ATOM   5921 O O     . VAL A 1 828 ? 132.117 156.868 125.370 1.00 159.43 ? 828 VAL A O     1 
ATOM   5922 C CB    . VAL A 1 828 ? 131.979 157.503 122.384 1.00 156.17 ? 828 VAL A CB    1 
ATOM   5923 C CG1   . VAL A 1 828 ? 133.435 157.885 122.160 1.00 152.68 ? 828 VAL A CG1   1 
ATOM   5924 C CG2   . VAL A 1 828 ? 131.220 157.469 121.066 1.00 151.44 ? 828 VAL A CG2   1 
ATOM   5925 N N     . ALA A 1 829 ? 133.680 155.452 124.572 1.00 165.38 ? 829 ALA A N     1 
ATOM   5926 C CA    . ALA A 1 829 ? 134.431 155.436 125.818 1.00 165.26 ? 829 ALA A CA    1 
ATOM   5927 C C     . ALA A 1 829 ? 135.226 156.726 125.982 1.00 164.99 ? 829 ALA A C     1 
ATOM   5928 O O     . ALA A 1 829 ? 135.795 157.252 125.022 1.00 166.96 ? 829 ALA A O     1 
ATOM   5929 C CB    . ALA A 1 829 ? 135.370 154.232 125.859 1.00 165.15 ? 829 ALA A CB    1 
ATOM   5930 N N     . SER A 1 830 ? 135.261 157.234 127.211 1.00 163.27 ? 830 SER A N     1 
ATOM   5931 C CA    . SER A 1 830 ? 136.018 158.437 127.518 1.00 163.39 ? 830 SER A CA    1 
ATOM   5932 C C     . SER A 1 830 ? 137.510 158.116 127.583 1.00 164.43 ? 830 SER A C     1 
ATOM   5933 O O     . SER A 1 830 ? 137.936 156.969 127.425 1.00 163.57 ? 830 SER A O     1 
ATOM   5934 C CB    . SER A 1 830 ? 135.528 159.052 128.827 1.00 162.85 ? 830 SER A CB    1 
ATOM   5935 O OG    . SER A 1 830 ? 135.695 158.150 129.908 1.00 160.16 ? 830 SER A OG    1 
ATOM   5936 N N     . HIS A 1 831 ? 138.321 159.152 127.809 1.00 165.65 ? 831 HIS A N     1 
ATOM   5937 C CA    . HIS A 1 831 ? 139.764 158.957 127.912 1.00 165.40 ? 831 HIS A CA    1 
ATOM   5938 C C     . HIS A 1 831 ? 140.113 158.075 129.106 1.00 167.07 ? 831 HIS A C     1 
ATOM   5939 O O     . HIS A 1 831 ? 140.894 157.123 128.985 1.00 166.55 ? 831 HIS A O     1 
ATOM   5940 C CB    . HIS A 1 831 ? 140.464 160.313 128.015 1.00 164.86 ? 831 HIS A CB    1 
ATOM   5941 C CG    . HIS A 1 831 ? 141.959 160.229 128.016 1.00 163.83 ? 831 HIS A CG    1 
ATOM   5942 N ND1   . HIS A 1 831 ? 142.760 161.255 128.470 1.00 161.11 ? 831 HIS A ND1   1 
ATOM   5943 C CD2   . HIS A 1 831 ? 142.798 159.247 127.612 1.00 166.31 ? 831 HIS A CD2   1 
ATOM   5944 C CE1   . HIS A 1 831 ? 144.028 160.906 128.350 1.00 162.65 ? 831 HIS A CE1   1 
ATOM   5945 N NE2   . HIS A 1 831 ? 144.079 159.693 127.831 1.00 166.30 ? 831 HIS A NE2   1 
ATOM   5946 N N     . ALA A 1 832 ? 139.531 158.373 130.271 1.00 168.00 ? 832 ALA A N     1 
ATOM   5947 C CA    . ALA A 1 832 ? 139.816 157.587 131.467 1.00 165.68 ? 832 ALA A CA    1 
ATOM   5948 C C     . ALA A 1 832 ? 139.323 156.153 131.322 1.00 167.79 ? 832 ALA A C     1 
ATOM   5949 O O     . ALA A 1 832 ? 140.023 155.209 131.708 1.00 167.87 ? 832 ALA A O     1 
ATOM   5950 C CB    . ALA A 1 832 ? 139.188 158.250 132.693 1.00 159.19 ? 832 ALA A CB    1 
ATOM   5951 N N     . GLU A 1 833 ? 138.121 155.969 130.771 1.00 167.44 ? 833 GLU A N     1 
ATOM   5952 C CA    . GLU A 1 833 ? 137.592 154.622 130.581 1.00 165.55 ? 833 GLU A CA    1 
ATOM   5953 C C     . GLU A 1 833 ? 138.445 153.826 129.601 1.00 165.09 ? 833 GLU A C     1 
ATOM   5954 O O     . GLU A 1 833 ? 138.739 152.647 129.835 1.00 163.71 ? 833 GLU A O     1 
ATOM   5955 C CB    . GLU A 1 833 ? 136.142 154.693 130.098 1.00 163.90 ? 833 GLU A CB    1 
ATOM   5956 C CG    . GLU A 1 833 ? 135.491 153.340 129.849 1.00 163.92 ? 833 GLU A CG    1 
ATOM   5957 C CD    . GLU A 1 833 ? 135.123 152.615 131.131 1.00 162.67 ? 833 GLU A CD    1 
ATOM   5958 O OE1   . GLU A 1 833 ? 135.245 153.216 132.219 1.00 162.94 ? 833 GLU A OE1   1 
ATOM   5959 O OE2   . GLU A 1 833 ? 134.705 151.441 131.048 1.00 160.59 ? 833 GLU A OE2   1 
ATOM   5960 N N     . THR A 1 834 ? 138.853 154.457 128.496 1.00 165.62 ? 834 THR A N     1 
ATOM   5961 C CA    . THR A 1 834 ? 139.705 153.774 127.529 1.00 164.48 ? 834 THR A CA    1 
ATOM   5962 C C     . THR A 1 834 ? 141.042 153.393 128.151 1.00 164.17 ? 834 THR A C     1 
ATOM   5963 O O     . THR A 1 834 ? 141.536 152.280 127.940 1.00 162.62 ? 834 THR A O     1 
ATOM   5964 C CB    . THR A 1 834 ? 139.918 154.655 126.296 1.00 163.95 ? 834 THR A CB    1 
ATOM   5965 O OG1   . THR A 1 834 ? 138.660 154.890 125.651 1.00 163.36 ? 834 THR A OG1   1 
ATOM   5966 C CG2   . THR A 1 834 ? 140.865 153.982 125.312 1.00 159.71 ? 834 THR A CG2   1 
ATOM   5967 N N     . LYS A 1 835 ? 141.638 154.303 128.928 1.00 165.69 ? 835 LYS A N     1 
ATOM   5968 C CA    . LYS A 1 835 ? 142.896 153.987 129.596 1.00 163.68 ? 835 LYS A CA    1 
ATOM   5969 C C     . LYS A 1 835 ? 142.725 152.834 130.576 1.00 162.18 ? 835 LYS A C     1 
ATOM   5970 O O     . LYS A 1 835 ? 143.579 151.944 130.652 1.00 160.14 ? 835 LYS A O     1 
ATOM   5971 C CB    . LYS A 1 835 ? 143.440 155.221 130.315 1.00 162.06 ? 835 LYS A CB    1 
ATOM   5972 C CG    . LYS A 1 835 ? 143.993 156.291 129.392 1.00 158.04 ? 835 LYS A CG    1 
ATOM   5973 C CD    . LYS A 1 835 ? 144.629 157.422 130.183 1.00 157.87 ? 835 LYS A CD    1 
ATOM   5974 C CE    . LYS A 1 835 ? 143.619 158.092 131.099 1.00 162.72 ? 835 LYS A CE    1 
ATOM   5975 N NZ    . LYS A 1 835 ? 144.229 159.204 131.878 1.00 161.70 ? 835 LYS A NZ    1 
ATOM   5976 N N     . ARG A 1 836 ? 141.625 152.830 131.333 1.00 162.15 ? 836 ARG A N     1 
ATOM   5977 C CA    . ARG A 1 836 ? 141.390 151.752 132.287 1.00 158.48 ? 836 ARG A CA    1 
ATOM   5978 C C     . ARG A 1 836 ? 141.235 150.411 131.581 1.00 159.36 ? 836 ARG A C     1 
ATOM   5979 O O     . ARG A 1 836 ? 141.783 149.398 132.029 1.00 157.99 ? 836 ARG A O     1 
ATOM   5980 C CB    . ARG A 1 836 ? 140.151 152.055 133.129 1.00 155.66 ? 836 ARG A CB    1 
ATOM   5981 C CG    . ARG A 1 836 ? 139.886 151.035 134.225 1.00 151.64 ? 836 ARG A CG    1 
ATOM   5982 C CD    . ARG A 1 836 ? 138.527 151.251 134.871 1.00 151.48 ? 836 ARG A CD    1 
ATOM   5983 N NE    . ARG A 1 836 ? 137.434 150.937 133.960 1.00 156.49 ? 836 ARG A NE    1 
ATOM   5984 C CZ    . ARG A 1 836 ? 136.871 149.741 133.850 1.00 155.10 ? 836 ARG A CZ    1 
ATOM   5985 N NH1   . ARG A 1 836 ? 137.275 148.717 134.585 1.00 151.99 ? 836 ARG A NH1   1 
ATOM   5986 N NH2   . ARG A 1 836 ? 135.878 149.568 132.983 1.00 153.75 ? 836 ARG A NH2   1 
ATOM   5987 N N     . ILE A 1 837 ? 140.487 150.384 130.476 1.00 160.29 ? 837 ILE A N     1 
ATOM   5988 C CA    . ILE A 1 837 ? 140.244 149.119 129.788 1.00 158.61 ? 837 ILE A CA    1 
ATOM   5989 C C     . ILE A 1 837 ? 141.509 148.624 129.093 1.00 158.00 ? 837 ILE A C     1 
ATOM   5990 O O     . ILE A 1 837 ? 141.805 147.423 129.103 1.00 156.88 ? 837 ILE A O     1 
ATOM   5991 C CB    . ILE A 1 837 ? 139.069 149.255 128.804 1.00 157.79 ? 837 ILE A CB    1 
ATOM   5992 C CG1   . ILE A 1 837 ? 137.803 149.689 129.543 1.00 158.99 ? 837 ILE A CG1   1 
ATOM   5993 C CG2   . ILE A 1 837 ? 138.810 147.933 128.102 1.00 153.65 ? 837 ILE A CG2   1 
ATOM   5994 C CD1   . ILE A 1 837 ? 136.599 149.867 128.643 1.00 159.17 ? 837 ILE A CD1   1 
ATOM   5995 N N     . VAL A 1 838 ? 142.281 149.528 128.491 1.00 159.03 ? 838 VAL A N     1 
ATOM   5996 C CA    . VAL A 1 838 ? 143.397 149.098 127.655 1.00 158.22 ? 838 VAL A CA    1 
ATOM   5997 C C     . VAL A 1 838 ? 144.689 148.905 128.450 1.00 156.09 ? 838 VAL A C     1 
ATOM   5998 O O     . VAL A 1 838 ? 145.559 148.134 128.030 1.00 150.00 ? 838 VAL A O     1 
ATOM   5999 C CB    . VAL A 1 838 ? 143.602 150.092 126.496 1.00 158.79 ? 838 VAL A CB    1 
ATOM   6000 C CG1   . VAL A 1 838 ? 144.399 151.309 126.950 1.00 157.85 ? 838 VAL A CG1   1 
ATOM   6001 C CG2   . VAL A 1 838 ? 144.278 149.407 125.319 1.00 151.26 ? 838 VAL A CG2   1 
ATOM   6002 N N     . GLY A 1 839 ? 144.841 149.579 129.588 1.00 158.27 ? 839 GLY A N     1 
ATOM   6003 C CA    . GLY A 1 839 ? 146.045 149.440 130.383 1.00 156.24 ? 839 GLY A CA    1 
ATOM   6004 C C     . GLY A 1 839 ? 145.843 148.578 131.610 1.00 155.79 ? 839 GLY A C     1 
ATOM   6005 O O     . GLY A 1 839 ? 146.798 148.280 132.333 1.00 153.79 ? 839 GLY A O     1 
ATOM   6006 N N     . ARG A 1 840 ? 144.592 148.181 131.854 1.00 158.19 ? 840 ARG A N     1 
ATOM   6007 C CA    . ARG A 1 840 ? 144.229 147.322 132.982 1.00 155.65 ? 840 ARG A CA    1 
ATOM   6008 C C     . ARG A 1 840 ? 144.618 147.944 134.321 1.00 151.95 ? 840 ARG A C     1 
ATOM   6009 O O     . ARG A 1 840 ? 144.910 147.234 135.286 1.00 147.56 ? 840 ARG A O     1 
ATOM   6010 C CB    . ARG A 1 840 ? 144.843 145.926 132.837 1.00 153.64 ? 840 ARG A CB    1 
ATOM   6011 C CG    . ARG A 1 840 ? 144.532 145.255 131.508 1.00 153.48 ? 840 ARG A CG    1 
ATOM   6012 C CD    . ARG A 1 840 ? 143.033 145.104 131.306 1.00 153.03 ? 840 ARG A CD    1 
ATOM   6013 N NE    . ARG A 1 840 ? 142.703 144.688 129.948 1.00 154.44 ? 840 ARG A NE    1 
ATOM   6014 C CZ    . ARG A 1 840 ? 142.620 143.427 129.548 1.00 154.38 ? 840 ARG A CZ    1 
ATOM   6015 N NH1   . ARG A 1 840 ? 142.844 142.422 130.379 1.00 152.53 ? 840 ARG A NH1   1 
ATOM   6016 N NH2   . ARG A 1 840 ? 142.305 143.167 128.282 1.00 155.24 ? 840 ARG A NH2   1 
ATOM   6017 N N     . ILE A 1 841 ? 144.631 149.277 134.391 1.00 153.57 ? 841 ILE A N     1 
ATOM   6018 C CA    . ILE A 1 841 ? 144.935 149.956 135.643 1.00 148.23 ? 841 ILE A CA    1 
ATOM   6019 C C     . ILE A 1 841 ? 143.761 149.813 136.602 1.00 141.19 ? 841 ILE A C     1 
ATOM   6020 O O     . ILE A 1 841 ? 142.590 149.911 136.206 1.00 140.50 ? 841 ILE A O     1 
ATOM   6021 C CB    . ILE A 1 841 ? 145.281 151.433 135.390 1.00 147.11 ? 841 ILE A CB    1 
ATOM   6022 C CG1   . ILE A 1 841 ? 144.176 152.116 134.584 1.00 147.85 ? 841 ILE A CG1   1 
ATOM   6023 C CG2   . ILE A 1 841 ? 146.619 151.551 134.676 1.00 148.24 ? 841 ILE A CG2   1 
ATOM   6024 C CD1   . ILE A 1 841 ? 144.441 153.577 134.297 1.00 146.53 ? 841 ILE A CD1   1 
ATOM   6025 N N     . ILE A 1 842 ? 144.072 149.569 137.872 1.00 134.71 ? 842 ILE A N     1 
ATOM   6026 C CA    . ILE A 1 842 ? 143.064 149.324 138.902 1.00 129.25 ? 842 ILE A CA    1 
ATOM   6027 C C     . ILE A 1 842 ? 142.611 150.642 139.517 1.00 125.55 ? 842 ILE A C     1 
ATOM   6028 O O     . ILE A 1 842 ? 143.448 151.413 140.008 1.00 123.93 ? 842 ILE A O     1 
ATOM   6029 C CB    . ILE A 1 842 ? 143.602 148.386 139.995 1.00 124.99 ? 842 ILE A CB    1 
ATOM   6030 C CG1   . ILE A 1 842 ? 144.062 147.057 139.394 1.00 122.72 ? 842 ILE A CG1   1 
ATOM   6031 C CG2   . ILE A 1 842 ? 142.544 148.154 141.066 1.00 116.05 ? 842 ILE A CG2   1 
ATOM   6032 C CD1   . ILE A 1 842 ? 144.662 146.104 140.409 1.00 102.42 ? 842 ILE A CD1   1 
ATOM   6033 N N     . PRO A 1 843 ? 141.312 150.947 139.512 1.00 125.23 ? 843 PRO A N     1 
ATOM   6034 C CA    . PRO A 1 843 ? 140.820 152.057 140.339 1.00 117.13 ? 843 PRO A CA    1 
ATOM   6035 C C     . PRO A 1 843 ? 141.078 151.776 141.810 1.00 109.24 ? 843 PRO A C     1 
ATOM   6036 O O     . PRO A 1 843 ? 140.533 150.819 142.369 1.00 101.41 ? 843 PRO A O     1 
ATOM   6037 C CB    . PRO A 1 843 ? 139.320 152.103 140.019 1.00 115.62 ? 843 PRO A CB    1 
ATOM   6038 C CG    . PRO A 1 843 ? 139.185 151.400 138.702 1.00 122.15 ? 843 PRO A CG    1 
ATOM   6039 C CD    . PRO A 1 843 ? 140.237 150.330 138.718 1.00 124.90 ? 843 PRO A CD    1 
ATOM   6040 N N     . ALA A 1 844 ? 141.912 152.595 142.444 1.00 99.23  ? 844 ALA A N     1 
ATOM   6041 C CA    . ALA A 1 844 ? 142.322 152.354 143.818 1.00 85.31  ? 844 ALA A CA    1 
ATOM   6042 C C     . ALA A 1 844 ? 142.290 153.656 144.602 1.00 76.52  ? 844 ALA A C     1 
ATOM   6043 O O     . ALA A 1 844 ? 142.538 154.736 144.060 1.00 80.29  ? 844 ALA A O     1 
ATOM   6044 C CB    . ALA A 1 844 ? 143.724 151.734 143.885 1.00 82.28  ? 844 ALA A CB    1 
ATOM   6045 N N     . VAL A 1 845 ? 141.983 153.535 145.892 1.00 67.41  ? 845 VAL A N     1 
ATOM   6046 C CA    . VAL A 1 845 ? 141.910 154.669 146.805 1.00 56.19  ? 845 VAL A CA    1 
ATOM   6047 C C     . VAL A 1 845 ? 142.746 154.340 148.035 1.00 53.09  ? 845 VAL A C     1 
ATOM   6048 O O     . VAL A 1 845 ? 142.712 153.212 148.539 1.00 51.92  ? 845 VAL A O     1 
ATOM   6049 C CB    . VAL A 1 845 ? 140.454 154.997 147.201 1.00 52.33  ? 845 VAL A CB    1 
ATOM   6050 C CG1   . VAL A 1 845 ? 140.405 156.231 148.085 1.00 52.01  ? 845 VAL A CG1   1 
ATOM   6051 C CG2   . VAL A 1 845 ? 139.591 155.191 145.962 1.00 58.73  ? 845 VAL A CG2   1 
ATOM   6052 N N     . VAL A 1 846 ? 143.512 155.328 148.507 1.00 51.26  ? 846 VAL A N     1 
ATOM   6053 C CA    . VAL A 1 846 ? 144.412 155.110 149.636 1.00 41.71  ? 846 VAL A CA    1 
ATOM   6054 C C     . VAL A 1 846 ? 143.638 154.797 150.910 1.00 37.16  ? 846 VAL A C     1 
ATOM   6055 O O     . VAL A 1 846 ? 144.109 154.027 151.757 1.00 41.69  ? 846 VAL A O     1 
ATOM   6056 C CB    . VAL A 1 846 ? 145.337 156.330 149.822 1.00 46.93  ? 846 VAL A CB    1 
ATOM   6057 C CG1   . VAL A 1 846 ? 146.178 156.554 148.581 1.00 56.37  ? 846 VAL A CG1   1 
ATOM   6058 C CG2   . VAL A 1 846 ? 144.528 157.575 150.140 1.00 47.92  ? 846 VAL A CG2   1 
ATOM   6059 N N     . THR A 1 847 ? 142.452 155.390 151.077 1.00 36.75  ? 847 THR A N     1 
ATOM   6060 C CA    . THR A 1 847 ? 141.680 155.183 152.299 1.00 35.50  ? 847 THR A CA    1 
ATOM   6061 C C     . THR A 1 847 ? 141.224 153.734 152.426 1.00 40.61  ? 847 THR A C     1 
ATOM   6062 O O     . THR A 1 847 ? 141.346 153.126 153.496 1.00 40.50  ? 847 THR A O     1 
ATOM   6063 C CB    . THR A 1 847 ? 140.482 156.132 152.333 1.00 36.73  ? 847 THR A CB    1 
ATOM   6064 O OG1   . THR A 1 847 ? 139.619 155.859 151.223 1.00 47.90  ? 847 THR A OG1   1 
ATOM   6065 C CG2   . THR A 1 847 ? 140.941 157.576 152.262 1.00 39.31  ? 847 THR A CG2   1 
ATOM   6066 N N     . THR A 1 848 ? 140.685 153.168 151.346 1.00 43.55  ? 848 THR A N     1 
ATOM   6067 C CA    . THR A 1 848 ? 140.317 151.758 151.365 1.00 37.78  ? 848 THR A CA    1 
ATOM   6068 C C     . THR A 1 848 ? 141.535 150.890 151.637 1.00 34.99  ? 848 THR A C     1 
ATOM   6069 O O     . THR A 1 848 ? 141.456 149.911 152.387 1.00 39.97  ? 848 THR A O     1 
ATOM   6070 C CB    . THR A 1 848 ? 139.661 151.364 150.041 1.00 40.94  ? 848 THR A CB    1 
ATOM   6071 O OG1   . THR A 1 848 ? 138.702 152.360 149.670 1.00 47.79  ? 848 THR A OG1   1 
ATOM   6072 C CG2   . THR A 1 848 ? 138.953 150.031 150.173 1.00 45.63  ? 848 THR A CG2   1 
ATOM   6073 N N     . THR A 1 849 ? 142.675 151.239 151.038 1.00 31.52  ? 849 THR A N     1 
ATOM   6074 C CA    . THR A 1 849 ? 143.909 150.501 151.280 1.00 31.47  ? 849 THR A CA    1 
ATOM   6075 C C     . THR A 1 849 ? 144.249 150.468 152.766 1.00 31.93  ? 849 THR A C     1 
ATOM   6076 O O     . THR A 1 849 ? 144.497 149.398 153.336 1.00 35.58  ? 849 THR A O     1 
ATOM   6077 C CB    . THR A 1 849 ? 145.046 151.135 150.478 1.00 34.20  ? 849 THR A CB    1 
ATOM   6078 O OG1   . THR A 1 849 ? 144.847 150.883 149.082 1.00 42.78  ? 849 THR A OG1   1 
ATOM   6079 C CG2   . THR A 1 849 ? 146.376 150.573 150.901 1.00 32.61  ? 849 THR A CG2   1 
ATOM   6080 N N     . ALA A 1 850 ? 144.235 151.633 153.416 1.00 30.17  ? 850 ALA A N     1 
ATOM   6081 C CA    . ALA A 1 850 ? 144.589 151.693 154.831 1.00 28.33  ? 850 ALA A CA    1 
ATOM   6082 C C     . ALA A 1 850 ? 143.573 150.954 155.693 1.00 29.46  ? 850 ALA A C     1 
ATOM   6083 O O     . ALA A 1 850 ? 143.950 150.249 156.635 1.00 34.05  ? 850 ALA A O     1 
ATOM   6084 C CB    . ALA A 1 850 ? 144.720 153.146 155.280 1.00 30.07  ? 850 ALA A CB    1 
ATOM   6085 N N     . ALA A 1 851 ? 142.282 151.099 155.389 1.00 26.60  ? 851 ALA A N     1 
ATOM   6086 C CA    . ALA A 1 851 ? 141.261 150.415 156.177 1.00 26.14  ? 851 ALA A CA    1 
ATOM   6087 C C     . ALA A 1 851 ? 141.409 148.903 156.069 1.00 29.37  ? 851 ALA A C     1 
ATOM   6088 O O     . ALA A 1 851 ? 141.324 148.179 157.070 1.00 31.10  ? 851 ALA A O     1 
ATOM   6089 C CB    . ALA A 1 851 ? 139.870 150.858 155.725 1.00 28.01  ? 851 ALA A CB    1 
ATOM   6090 N N     . VAL A 1 852 ? 141.641 148.408 154.853 1.00 29.44  ? 852 VAL A N     1 
ATOM   6091 C CA    . VAL A 1 852 ? 141.774 146.972 154.643 1.00 29.90  ? 852 VAL A CA    1 
ATOM   6092 C C     . VAL A 1 852 ? 143.035 146.445 155.317 1.00 31.62  ? 852 VAL A C     1 
ATOM   6093 O O     . VAL A 1 852 ? 143.030 145.356 155.907 1.00 39.41  ? 852 VAL A O     1 
ATOM   6094 C CB    . VAL A 1 852 ? 141.741 146.657 153.137 1.00 32.31  ? 852 VAL A CB    1 
ATOM   6095 C CG1   . VAL A 1 852 ? 142.007 145.201 152.906 1.00 38.73  ? 852 VAL A CG1   1 
ATOM   6096 C CG2   . VAL A 1 852 ? 140.386 147.024 152.558 1.00 35.07  ? 852 VAL A CG2   1 
ATOM   6097 N N     . ALA A 1 853 ? 144.132 147.207 155.253 1.00 25.32  ? 853 ALA A N     1 
ATOM   6098 C CA    . ALA A 1 853 ? 145.352 146.793 155.940 1.00 22.90  ? 853 ALA A CA    1 
ATOM   6099 C C     . ALA A 1 853 ? 145.153 146.758 157.449 1.00 26.90  ? 853 ALA A C     1 
ATOM   6100 O O     . ALA A 1 853 ? 145.675 145.869 158.131 1.00 32.40  ? 853 ALA A O     1 
ATOM   6101 C CB    . ALA A 1 853 ? 146.506 147.721 155.575 1.00 23.93  ? 853 ALA A CB    1 
ATOM   6102 N N     . GLY A 1 854 ? 144.408 147.722 157.990 1.00 25.71  ? 854 GLY A N     1 
ATOM   6103 C CA    . GLY A 1 854 ? 144.102 147.694 159.409 1.00 24.61  ? 854 GLY A CA    1 
ATOM   6104 C C     . GLY A 1 854 ? 143.265 146.494 159.805 1.00 26.22  ? 854 GLY A C     1 
ATOM   6105 O O     . GLY A 1 854 ? 143.495 145.882 160.850 1.00 32.23  ? 854 GLY A O     1 
ATOM   6106 N N     . LEU A 1 855 ? 142.281 146.139 158.977 1.00 22.70  ? 855 LEU A N     1 
ATOM   6107 C CA    . LEU A 1 855 ? 141.473 144.956 159.265 1.00 21.22  ? 855 LEU A CA    1 
ATOM   6108 C C     . LEU A 1 855 ? 142.316 143.686 159.207 1.00 25.23  ? 855 LEU A C     1 
ATOM   6109 O O     . LEU A 1 855 ? 142.155 142.777 160.037 1.00 29.63  ? 855 LEU A O     1 
ATOM   6110 C CB    . LEU A 1 855 ? 140.299 144.879 158.294 1.00 23.15  ? 855 LEU A CB    1 
ATOM   6111 C CG    . LEU A 1 855 ? 139.244 145.976 158.448 1.00 29.86  ? 855 LEU A CG    1 
ATOM   6112 C CD1   . LEU A 1 855 ? 138.213 145.884 157.343 1.00 35.96  ? 855 LEU A CD1   1 
ATOM   6113 C CD2   . LEU A 1 855 ? 138.575 145.885 159.802 1.00 31.28  ? 855 LEU A CD2   1 
ATOM   6114 N N     . VAL A 1 856 ? 143.231 143.612 158.241 1.00 25.32  ? 856 VAL A N     1 
ATOM   6115 C CA    . VAL A 1 856 ? 144.143 142.477 158.167 1.00 25.57  ? 856 VAL A CA    1 
ATOM   6116 C C     . VAL A 1 856 ? 145.025 142.412 159.409 1.00 25.99  ? 856 VAL A C     1 
ATOM   6117 O O     . VAL A 1 856 ? 145.258 141.334 159.960 1.00 29.75  ? 856 VAL A O     1 
ATOM   6118 C CB    . VAL A 1 856 ? 144.974 142.549 156.874 1.00 26.53  ? 856 VAL A CB    1 
ATOM   6119 C CG1   . VAL A 1 856 ? 146.093 141.527 156.905 1.00 30.06  ? 856 VAL A CG1   1 
ATOM   6120 C CG2   . VAL A 1 856 ? 144.075 142.324 155.672 1.00 31.08  ? 856 VAL A CG2   1 
ATOM   6121 N N     . GLY A 1 857 ? 145.527 143.557 159.873 1.00 24.76  ? 857 GLY A N     1 
ATOM   6122 C CA    . GLY A 1 857 ? 146.306 143.562 161.104 1.00 25.17  ? 857 GLY A CA    1 
ATOM   6123 C C     . GLY A 1 857 ? 145.496 143.129 162.313 1.00 24.12  ? 857 GLY A C     1 
ATOM   6124 O O     . GLY A 1 857 ? 146.005 142.447 163.209 1.00 26.06  ? 857 GLY A O     1 
ATOM   6125 N N     . LEU A 1 858 ? 144.221 143.517 162.354 1.00 24.50  ? 858 LEU A N     1 
ATOM   6126 C CA    . LEU A 1 858 ? 143.348 143.081 163.438 1.00 23.81  ? 858 LEU A CA    1 
ATOM   6127 C C     . LEU A 1 858 ? 143.177 141.569 163.436 1.00 26.32  ? 858 LEU A C     1 
ATOM   6128 O O     . LEU A 1 858 ? 143.146 140.940 164.500 1.00 30.20  ? 858 LEU A O     1 
ATOM   6129 C CB    . LEU A 1 858 ? 141.990 143.766 163.328 1.00 23.16  ? 858 LEU A CB    1 
ATOM   6130 C CG    . LEU A 1 858 ? 141.969 145.245 163.688 1.00 28.25  ? 858 LEU A CG    1 
ATOM   6131 C CD1   . LEU A 1 858 ? 140.602 145.819 163.412 1.00 29.09  ? 858 LEU A CD1   1 
ATOM   6132 C CD2   . LEU A 1 858 ? 142.345 145.429 165.142 1.00 25.08  ? 858 LEU A CD2   1 
ATOM   6133 N N     . GLU A 1 859 ? 143.050 140.970 162.251 1.00 26.28  ? 859 GLU A N     1 
ATOM   6134 C CA    . GLU A 1 859 ? 142.983 139.512 162.185 1.00 25.33  ? 859 GLU A CA    1 
ATOM   6135 C C     . GLU A 1 859 ? 144.326 138.881 162.533 1.00 22.35  ? 859 GLU A C     1 
ATOM   6136 O O     . GLU A 1 859 ? 144.378 137.788 163.111 1.00 27.82  ? 859 GLU A O     1 
ATOM   6137 C CB    . GLU A 1 859 ? 142.511 139.070 160.803 1.00 26.95  ? 859 GLU A CB    1 
ATOM   6138 C CG    . GLU A 1 859 ? 141.120 139.563 160.468 1.00 30.45  ? 859 GLU A CG    1 
ATOM   6139 C CD    . GLU A 1 859 ? 140.110 139.214 161.544 1.00 32.97  ? 859 GLU A CD    1 
ATOM   6140 O OE1   . GLU A 1 859 ? 139.923 138.012 161.824 1.00 32.69  ? 859 GLU A OE1   1 
ATOM   6141 O OE2   . GLU A 1 859 ? 139.508 140.144 162.116 1.00 29.50  ? 859 GLU A OE2   1 
ATOM   6142 N N     . LEU A 1 860 ? 145.421 139.552 162.178 1.00 20.67  ? 860 LEU A N     1 
ATOM   6143 C CA    . LEU A 1 860 ? 146.753 139.087 162.547 1.00 21.62  ? 860 LEU A CA    1 
ATOM   6144 C C     . LEU A 1 860 ? 146.932 139.043 164.057 1.00 23.97  ? 860 LEU A C     1 
ATOM   6145 O O     . LEU A 1 860 ? 147.645 138.174 164.575 1.00 26.72  ? 860 LEU A O     1 
ATOM   6146 C CB    . LEU A 1 860 ? 147.804 139.992 161.906 1.00 21.29  ? 860 LEU A CB    1 
ATOM   6147 C CG    . LEU A 1 860 ? 149.214 140.012 162.484 1.00 23.26  ? 860 LEU A CG    1 
ATOM   6148 C CD1   . LEU A 1 860 ? 149.914 138.700 162.246 1.00 24.63  ? 860 LEU A CD1   1 
ATOM   6149 C CD2   . LEU A 1 860 ? 150.000 141.144 161.871 1.00 27.20  ? 860 LEU A CD2   1 
ATOM   6150 N N     . TYR A 1 861 ? 146.302 139.973 164.774 1.00 24.68  ? 861 TYR A N     1 
ATOM   6151 C CA    . TYR A 1 861 ? 146.340 139.927 166.233 1.00 25.09  ? 861 TYR A CA    1 
ATOM   6152 C C     . TYR A 1 861 ? 145.801 138.597 166.749 1.00 27.34  ? 861 TYR A C     1 
ATOM   6153 O O     . TYR A 1 861 ? 146.395 137.974 167.636 1.00 28.35  ? 861 TYR A O     1 
ATOM   6154 C CB    . TYR A 1 861 ? 145.542 141.089 166.824 1.00 27.13  ? 861 TYR A CB    1 
ATOM   6155 C CG    . TYR A 1 861 ? 146.312 142.384 166.950 1.00 30.87  ? 861 TYR A CG    1 
ATOM   6156 C CD1   . TYR A 1 861 ? 147.695 142.388 167.069 1.00 30.86  ? 861 TYR A CD1   1 
ATOM   6157 C CD2   . TYR A 1 861 ? 145.655 143.606 166.958 1.00 30.79  ? 861 TYR A CD2   1 
ATOM   6158 C CE1   . TYR A 1 861 ? 148.399 143.572 167.188 1.00 29.88  ? 861 TYR A CE1   1 
ATOM   6159 C CE2   . TYR A 1 861 ? 146.354 144.796 167.078 1.00 32.86  ? 861 TYR A CE2   1 
ATOM   6160 C CZ    . TYR A 1 861 ? 147.725 144.772 167.192 1.00 32.61  ? 861 TYR A CZ    1 
ATOM   6161 O OH    . TYR A 1 861 ? 148.427 145.949 167.312 1.00 36.22  ? 861 TYR A OH    1 
ATOM   6162 N N     . LYS A 1 862 ? 144.673 138.144 166.199 1.00 25.56  ? 862 LYS A N     1 
ATOM   6163 C CA    . LYS A 1 862 ? 144.089 136.882 166.640 1.00 20.78  ? 862 LYS A CA    1 
ATOM   6164 C C     . LYS A 1 862 ? 144.881 135.684 166.137 1.00 23.18  ? 862 LYS A C     1 
ATOM   6165 O O     . LYS A 1 862 ? 144.956 134.660 166.826 1.00 32.72  ? 862 LYS A O     1 
ATOM   6166 C CB    . LYS A 1 862 ? 142.635 136.797 166.188 1.00 22.28  ? 862 LYS A CB    1 
ATOM   6167 C CG    . LYS A 1 862 ? 141.737 137.792 166.886 1.00 23.71  ? 862 LYS A CG    1 
ATOM   6168 C CD    . LYS A 1 862 ? 140.294 137.648 166.458 1.00 23.93  ? 862 LYS A CD    1 
ATOM   6169 C CE    . LYS A 1 862 ? 140.106 138.060 165.017 1.00 23.98  ? 862 LYS A CE    1 
ATOM   6170 N NZ    . LYS A 1 862 ? 140.519 139.466 164.787 1.00 27.00  ? 862 LYS A NZ    1 
ATOM   6171 N N     . VAL A 1 863 ? 145.466 135.784 164.943 1.00 23.04  ? 863 VAL A N     1 
ATOM   6172 C CA    . VAL A 1 863 ? 146.297 134.696 164.437 1.00 24.40  ? 863 VAL A CA    1 
ATOM   6173 C C     . VAL A 1 863 ? 147.502 134.475 165.344 1.00 26.83  ? 863 VAL A C     1 
ATOM   6174 O O     . VAL A 1 863 ? 147.848 133.335 165.673 1.00 28.21  ? 863 VAL A O     1 
ATOM   6175 C CB    . VAL A 1 863 ? 146.724 134.972 162.985 1.00 26.13  ? 863 VAL A CB    1 
ATOM   6176 C CG1   . VAL A 1 863 ? 147.689 133.902 162.515 1.00 30.24  ? 863 VAL A CG1   1 
ATOM   6177 C CG2   . VAL A 1 863 ? 145.511 135.019 162.078 1.00 24.96  ? 863 VAL A CG2   1 
ATOM   6178 N N     . VAL A 1 864 ? 148.157 135.560 165.768 1.00 26.00  ? 864 VAL A N     1 
ATOM   6179 C CA    . VAL A 1 864 ? 149.301 135.429 166.664 1.00 25.28  ? 864 VAL A CA    1 
ATOM   6180 C C     . VAL A 1 864 ? 148.870 135.013 168.066 1.00 25.74  ? 864 VAL A C     1 
ATOM   6181 O O     . VAL A 1 864 ? 149.649 134.383 168.791 1.00 25.82  ? 864 VAL A O     1 
ATOM   6182 C CB    . VAL A 1 864 ? 150.108 136.745 166.677 1.00 24.89  ? 864 VAL A CB    1 
ATOM   6183 C CG1   . VAL A 1 864 ? 151.195 136.721 167.739 1.00 22.80  ? 864 VAL A CG1   1 
ATOM   6184 C CG2   . VAL A 1 864 ? 150.729 136.990 165.312 1.00 24.94  ? 864 VAL A CG2   1 
ATOM   6185 N N     . GLY A 1 865 ? 147.627 135.294 168.448 1.00 28.09  ? 865 GLY A N     1 
ATOM   6186 C CA    . GLY A 1 865 ? 147.134 134.974 169.775 1.00 29.31  ? 865 GLY A CA    1 
ATOM   6187 C C     . GLY A 1 865 ? 146.909 133.499 170.048 1.00 34.36  ? 865 GLY A C     1 
ATOM   6188 O O     . GLY A 1 865 ? 146.213 133.142 171.002 1.00 40.82  ? 865 GLY A O     1 
ATOM   6189 N N     . GLY A 1 866 ? 147.485 132.633 169.218 1.00 33.09  ? 866 GLY A N     1 
ATOM   6190 C CA    . GLY A 1 866 ? 147.409 131.209 169.426 1.00 32.36  ? 866 GLY A CA    1 
ATOM   6191 C C     . GLY A 1 866 ? 146.100 130.620 168.947 1.00 35.00  ? 866 GLY A C     1 
ATOM   6192 O O     . GLY A 1 866 ? 145.405 131.195 168.104 1.00 36.02  ? 866 GLY A O     1 
ATOM   6193 N N     . PRO A 1 867 ? 145.749 129.446 169.469 1.00 37.62  ? 867 PRO A N     1 
ATOM   6194 C CA    . PRO A 1 867 ? 144.491 128.809 169.066 1.00 31.94  ? 867 PRO A CA    1 
ATOM   6195 C C     . PRO A 1 867 ? 143.293 129.690 169.382 1.00 31.06  ? 867 PRO A C     1 
ATOM   6196 O O     . PRO A 1 867 ? 143.216 130.313 170.443 1.00 35.80  ? 867 PRO A O     1 
ATOM   6197 C CB    . PRO A 1 867 ? 144.471 127.516 169.889 1.00 32.18  ? 867 PRO A CB    1 
ATOM   6198 C CG    . PRO A 1 867 ? 145.904 127.254 170.220 1.00 37.69  ? 867 PRO A CG    1 
ATOM   6199 C CD    . PRO A 1 867 ? 146.529 128.605 170.391 1.00 38.27  ? 867 PRO A CD    1 
ATOM   6200 N N     . ARG A 1 868 ? 142.355 129.736 168.445 1.00 28.99  ? 868 ARG A N     1 
ATOM   6201 C CA    . ARG A 1 868 ? 141.133 130.509 168.583 1.00 32.76  ? 868 ARG A CA    1 
ATOM   6202 C C     . ARG A 1 868 ? 139.976 129.722 167.993 1.00 31.73  ? 868 ARG A C     1 
ATOM   6203 O O     . ARG A 1 868 ? 140.165 128.948 167.048 1.00 34.34  ? 868 ARG A O     1 
ATOM   6204 C CB    . ARG A 1 868 ? 141.231 131.868 167.872 1.00 27.66  ? 868 ARG A CB    1 
ATOM   6205 C CG    . ARG A 1 868 ? 142.157 132.867 168.525 1.00 30.44  ? 868 ARG A CG    1 
ATOM   6206 C CD    . ARG A 1 868 ? 141.647 133.259 169.892 1.00 35.22  ? 868 ARG A CD    1 
ATOM   6207 N NE    . ARG A 1 868 ? 142.370 134.402 170.430 1.00 33.35  ? 868 ARG A NE    1 
ATOM   6208 C CZ    . ARG A 1 868 ? 141.955 135.657 170.341 1.00 32.58  ? 868 ARG A CZ    1 
ATOM   6209 N NH1   . ARG A 1 868 ? 140.815 135.967 169.749 1.00 36.96  ? 868 ARG A NH1   1 
ATOM   6210 N NH2   . ARG A 1 868 ? 142.703 136.624 170.863 1.00 32.35  ? 868 ARG A NH2   1 
ATOM   6211 N N     . PRO A 1 869 ? 138.772 129.896 168.527 1.00 25.66  ? 869 PRO A N     1 
ATOM   6212 C CA    . PRO A 1 869 ? 137.596 129.321 167.877 1.00 21.06  ? 869 PRO A CA    1 
ATOM   6213 C C     . PRO A 1 869 ? 137.259 130.080 166.604 1.00 28.69  ? 869 PRO A C     1 
ATOM   6214 O O     . PRO A 1 869 ? 137.715 131.201 166.371 1.00 30.56  ? 869 PRO A O     1 
ATOM   6215 C CB    . PRO A 1 869 ? 136.495 129.478 168.929 1.00 23.11  ? 869 PRO A CB    1 
ATOM   6216 C CG    . PRO A 1 869 ? 136.929 130.638 169.743 1.00 30.26  ? 869 PRO A CG    1 
ATOM   6217 C CD    . PRO A 1 869 ? 138.430 130.572 169.788 1.00 33.26  ? 869 PRO A CD    1 
ATOM   6218 N N     . ARG A 1 870 ? 136.448 129.434 165.765 1.00 28.45  ? 870 ARG A N     1 
ATOM   6219 C CA    . ARG A 1 870 ? 136.017 130.061 164.522 1.00 23.85  ? 870 ARG A CA    1 
ATOM   6220 C C     . ARG A 1 870 ? 135.249 131.351 164.780 1.00 28.48  ? 870 ARG A C     1 
ATOM   6221 O O     . ARG A 1 870 ? 135.330 132.292 163.982 1.00 33.00  ? 870 ARG A O     1 
ATOM   6222 C CB    . ARG A 1 870 ? 135.165 129.077 163.718 1.00 27.80  ? 870 ARG A CB    1 
ATOM   6223 C CG    . ARG A 1 870 ? 134.593 129.638 162.431 1.00 27.34  ? 870 ARG A CG    1 
ATOM   6224 C CD    . ARG A 1 870 ? 133.751 128.607 161.710 1.00 24.69  ? 870 ARG A CD    1 
ATOM   6225 N NE    . ARG A 1 870 ? 132.642 128.126 162.524 1.00 23.97  ? 870 ARG A NE    1 
ATOM   6226 C CZ    . ARG A 1 870 ? 131.422 128.643 162.511 1.00 26.89  ? 870 ARG A CZ    1 
ATOM   6227 N NH1   . ARG A 1 870 ? 131.115 129.670 161.739 1.00 31.79  ? 870 ARG A NH1   1 
ATOM   6228 N NH2   . ARG A 1 870 ? 130.486 128.115 163.294 1.00 31.23  ? 870 ARG A NH2   1 
ATOM   6229 N N     . HIS A 1 871 ? 134.510 131.421 165.889 1.00 25.79  ? 871 HIS A N     1 
ATOM   6230 C CA    . HIS A 1 871 ? 133.725 132.610 166.195 1.00 23.41  ? 871 HIS A CA    1 
ATOM   6231 C C     . HIS A 1 871 ? 134.592 133.825 166.491 1.00 26.98  ? 871 HIS A C     1 
ATOM   6232 O O     . HIS A 1 871 ? 134.092 134.953 166.442 1.00 30.59  ? 871 HIS A O     1 
ATOM   6233 C CB    . HIS A 1 871 ? 132.800 132.337 167.380 1.00 26.45  ? 871 HIS A CB    1 
ATOM   6234 C CG    . HIS A 1 871 ? 131.891 131.165 167.180 1.00 40.83  ? 871 HIS A CG    1 
ATOM   6235 N ND1   . HIS A 1 871 ? 130.745 131.234 166.419 1.00 46.86  ? 871 HIS A ND1   1 
ATOM   6236 C CD2   . HIS A 1 871 ? 131.958 129.896 167.646 1.00 41.04  ? 871 HIS A CD2   1 
ATOM   6237 C CE1   . HIS A 1 871 ? 130.145 130.057 166.423 1.00 42.48  ? 871 HIS A CE1   1 
ATOM   6238 N NE2   . HIS A 1 871 ? 130.861 129.227 167.160 1.00 39.16  ? 871 HIS A NE2   1 
ATOM   6239 N N     . ALA A 1 872 ? 135.874 133.622 166.804 1.00 27.87  ? 872 ALA A N     1 
ATOM   6240 C CA    . ALA A 1 872 ? 136.757 134.749 167.077 1.00 26.02  ? 872 ALA A CA    1 
ATOM   6241 C C     . ALA A 1 872 ? 137.101 135.512 165.803 1.00 25.50  ? 872 ALA A C     1 
ATOM   6242 O O     . ALA A 1 872 ? 137.072 136.747 165.785 1.00 26.47  ? 872 ALA A O     1 
ATOM   6243 C CB    . ALA A 1 872 ? 138.030 134.259 167.764 1.00 27.42  ? 872 ALA A CB    1 
ATOM   6244 N N     . PHE A 1 873 ? 137.427 134.796 164.732 1.00 26.29  ? 873 PHE A N     1 
ATOM   6245 C CA    . PHE A 1 873 ? 137.868 135.435 163.503 1.00 24.35  ? 873 PHE A CA    1 
ATOM   6246 C C     . PHE A 1 873 ? 136.698 136.084 162.773 1.00 24.98  ? 873 PHE A C     1 
ATOM   6247 O O     . PHE A 1 873 ? 135.549 135.653 162.885 1.00 26.09  ? 873 PHE A O     1 
ATOM   6248 C CB    . PHE A 1 873 ? 138.558 134.419 162.599 1.00 22.51  ? 873 PHE A CB    1 
ATOM   6249 C CG    . PHE A 1 873 ? 139.788 133.815 163.203 1.00 22.69  ? 873 PHE A CG    1 
ATOM   6250 C CD1   . PHE A 1 873 ? 141.020 134.423 163.046 1.00 24.29  ? 873 PHE A CD1   1 
ATOM   6251 C CD2   . PHE A 1 873 ? 139.715 132.643 163.928 1.00 26.68  ? 873 PHE A CD2   1 
ATOM   6252 C CE1   . PHE A 1 873 ? 142.152 133.872 163.598 1.00 26.48  ? 873 PHE A CE1   1 
ATOM   6253 C CE2   . PHE A 1 873 ? 140.844 132.087 164.481 1.00 32.90  ? 873 PHE A CE2   1 
ATOM   6254 C CZ    . PHE A 1 873 ? 142.064 132.703 164.319 1.00 32.44  ? 873 PHE A CZ    1 
ATOM   6255 N N     . ARG A 1 874 ? 137.004 137.143 162.028 1.00 22.44  ? 874 ARG A N     1 
ATOM   6256 C CA    . ARG A 1 874 ? 136.010 137.886 161.271 1.00 19.71  ? 874 ARG A CA    1 
ATOM   6257 C C     . ARG A 1 874 ? 136.509 138.128 159.856 1.00 23.07  ? 874 ARG A C     1 
ATOM   6258 O O     . ARG A 1 874 ? 137.685 138.435 159.647 1.00 22.57  ? 874 ARG A O     1 
ATOM   6259 C CB    . ARG A 1 874 ? 135.688 139.234 161.932 1.00 24.49  ? 874 ARG A CB    1 
ATOM   6260 C CG    . ARG A 1 874 ? 135.279 139.142 163.386 1.00 25.55  ? 874 ARG A CG    1 
ATOM   6261 C CD    . ARG A 1 874 ? 133.927 138.493 163.545 1.00 22.61  ? 874 ARG A CD    1 
ATOM   6262 N NE    . ARG A 1 874 ? 133.760 137.903 164.867 1.00 22.22  ? 874 ARG A NE    1 
ATOM   6263 C CZ    . ARG A 1 874 ? 133.108 138.475 165.868 1.00 24.58  ? 874 ARG A CZ    1 
ATOM   6264 N NH1   . ARG A 1 874 ? 132.546 139.665 165.738 1.00 29.79  ? 874 ARG A NH1   1 
ATOM   6265 N NH2   . ARG A 1 874 ? 133.012 137.835 167.029 1.00 26.16  ? 874 ARG A NH2   1 
ATOM   6266 N N     . HIS A 1 875 ? 135.610 137.974 158.891 1.00 27.15  ? 875 HIS A N     1 
ATOM   6267 C CA    . HIS A 1 875 ? 135.798 138.506 157.551 1.00 28.22  ? 875 HIS A CA    1 
ATOM   6268 C C     . HIS A 1 875 ? 135.087 139.848 157.452 1.00 27.61  ? 875 HIS A C     1 
ATOM   6269 O O     . HIS A 1 875 ? 134.027 140.053 158.047 1.00 29.56  ? 875 HIS A O     1 
ATOM   6270 C CB    . HIS A 1 875 ? 135.250 137.547 156.493 1.00 28.26  ? 875 HIS A CB    1 
ATOM   6271 C CG    . HIS A 1 875 ? 136.129 136.368 156.227 1.00 24.01  ? 875 HIS A CG    1 
ATOM   6272 N ND1   . HIS A 1 875 ? 135.878 135.470 155.215 1.00 25.40  ? 875 HIS A ND1   1 
ATOM   6273 C CD2   . HIS A 1 875 ? 137.256 135.940 156.839 1.00 25.48  ? 875 HIS A CD2   1 
ATOM   6274 C CE1   . HIS A 1 875 ? 136.814 134.539 155.213 1.00 31.55  ? 875 HIS A CE1   1 
ATOM   6275 N NE2   . HIS A 1 875 ? 137.662 134.800 156.190 1.00 27.77  ? 875 HIS A NE2   1 
ATOM   6276 N N     . SER A 1 876 ? 135.673 140.768 156.693 1.00 29.61  ? 876 SER A N     1 
ATOM   6277 C CA    . SER A 1 876 ? 135.157 142.127 156.648 1.00 33.39  ? 876 SER A CA    1 
ATOM   6278 C C     . SER A 1 876 ? 135.037 142.610 155.213 1.00 36.40  ? 876 SER A C     1 
ATOM   6279 O O     . SER A 1 876 ? 135.941 142.405 154.396 1.00 40.05  ? 876 SER A O     1 
ATOM   6280 C CB    . SER A 1 876 ? 136.052 143.083 157.441 1.00 39.09  ? 876 SER A CB    1 
ATOM   6281 O OG    . SER A 1 876 ? 136.289 142.595 158.750 1.00 48.59  ? 876 SER A OG    1 
ATOM   6282 N N     . TYR A 1 877 ? 133.915 143.265 154.926 1.00 35.01  ? 877 TYR A N     1 
ATOM   6283 C CA    . TYR A 1 877 ? 133.686 143.937 153.656 1.00 37.84  ? 877 TYR A CA    1 
ATOM   6284 C C     . TYR A 1 877 ? 133.212 145.354 153.936 1.00 41.07  ? 877 TYR A C     1 
ATOM   6285 O O     . TYR A 1 877 ? 132.282 145.558 154.723 1.00 44.71  ? 877 TYR A O     1 
ATOM   6286 C CB    . TYR A 1 877 ? 132.659 143.187 152.804 1.00 43.39  ? 877 TYR A CB    1 
ATOM   6287 C CG    . TYR A 1 877 ? 132.621 143.637 151.363 1.00 42.00  ? 877 TYR A CG    1 
ATOM   6288 C CD1   . TYR A 1 877 ? 133.449 143.060 150.416 1.00 41.76  ? 877 TYR A CD1   1 
ATOM   6289 C CD2   . TYR A 1 877 ? 131.759 144.643 150.951 1.00 41.48  ? 877 TYR A CD2   1 
ATOM   6290 C CE1   . TYR A 1 877 ? 133.421 143.466 149.101 1.00 46.13  ? 877 TYR A CE1   1 
ATOM   6291 C CE2   . TYR A 1 877 ? 131.726 145.060 149.634 1.00 43.45  ? 877 TYR A CE2   1 
ATOM   6292 C CZ    . TYR A 1 877 ? 132.560 144.466 148.714 1.00 49.80  ? 877 TYR A CZ    1 
ATOM   6293 O OH    . TYR A 1 877 ? 132.534 144.866 147.397 1.00 59.04  ? 877 TYR A OH    1 
ATOM   6294 N N     . LEU A 1 878 ? 133.842 146.327 153.283 1.00 39.34  ? 878 LEU A N     1 
ATOM   6295 C CA    . LEU A 1 878 ? 133.564 147.735 153.512 1.00 41.84  ? 878 LEU A CA    1 
ATOM   6296 C C     . LEU A 1 878 ? 133.369 148.445 152.182 1.00 47.40  ? 878 LEU A C     1 
ATOM   6297 O O     . LEU A 1 878 ? 134.079 148.177 151.211 1.00 49.58  ? 878 LEU A O     1 
ATOM   6298 C CB    . LEU A 1 878 ? 134.700 148.400 154.307 1.00 44.31  ? 878 LEU A CB    1 
ATOM   6299 C CG    . LEU A 1 878 ? 136.076 148.484 153.641 1.00 45.09  ? 878 LEU A CG    1 
ATOM   6300 C CD1   . LEU A 1 878 ? 136.388 149.910 153.221 1.00 43.69  ? 878 LEU A CD1   1 
ATOM   6301 C CD2   . LEU A 1 878 ? 137.159 147.945 154.555 1.00 43.48  ? 878 LEU A CD2   1 
ATOM   6302 N N     . HIS A 1 879 ? 132.389 149.343 152.146 1.00 47.88  ? 879 HIS A N     1 
ATOM   6303 C CA    . HIS A 1 879 ? 132.108 150.183 150.983 1.00 49.42  ? 879 HIS A CA    1 
ATOM   6304 C C     . HIS A 1 879 ? 131.859 151.582 151.535 1.00 51.81  ? 879 HIS A C     1 
ATOM   6305 O O     . HIS A 1 879 ? 130.768 151.877 152.035 1.00 50.28  ? 879 HIS A O     1 
ATOM   6306 C CB    . HIS A 1 879 ? 130.913 149.665 150.187 1.00 53.76  ? 879 HIS A CB    1 
ATOM   6307 C CG    . HIS A 1 879 ? 130.720 150.353 148.872 1.00 53.44  ? 879 HIS A CG    1 
ATOM   6308 N ND1   . HIS A 1 879 ? 129.524 150.346 148.189 1.00 54.88  ? 879 HIS A ND1   1 
ATOM   6309 C CD2   . HIS A 1 879 ? 131.582 151.064 148.109 1.00 53.68  ? 879 HIS A CD2   1 
ATOM   6310 C CE1   . HIS A 1 879 ? 129.657 151.027 147.065 1.00 58.50  ? 879 HIS A CE1   1 
ATOM   6311 N NE2   . HIS A 1 879 ? 130.898 151.471 146.991 1.00 58.43  ? 879 HIS A NE2   1 
ATOM   6312 N N     . LEU A 1 880 ? 132.881 152.433 151.460 1.00 52.73  ? 880 LEU A N     1 
ATOM   6313 C CA    . LEU A 1 880 ? 132.818 153.729 152.122 1.00 49.73  ? 880 LEU A CA    1 
ATOM   6314 C C     . LEU A 1 880 ? 131.882 154.697 151.412 1.00 52.06  ? 880 LEU A C     1 
ATOM   6315 O O     . LEU A 1 880 ? 131.299 155.571 152.061 1.00 53.48  ? 880 LEU A O     1 
ATOM   6316 C CB    . LEU A 1 880 ? 134.223 154.320 152.227 1.00 48.48  ? 880 LEU A CB    1 
ATOM   6317 C CG    . LEU A 1 880 ? 135.260 153.404 152.880 1.00 49.10  ? 880 LEU A CG    1 
ATOM   6318 C CD1   . LEU A 1 880 ? 136.641 154.042 152.844 1.00 44.32  ? 880 LEU A CD1   1 
ATOM   6319 C CD2   . LEU A 1 880 ? 134.849 153.071 154.308 1.00 47.66  ? 880 LEU A CD2   1 
ATOM   6320 N N     . ALA A 1 881 ? 131.707 154.549 150.096 1.00 51.70  ? 881 ALA A N     1 
ATOM   6321 C CA    . ALA A 1 881 ? 130.887 155.488 149.340 1.00 50.29  ? 881 ALA A CA    1 
ATOM   6322 C C     . ALA A 1 881 ? 129.427 155.477 149.775 1.00 52.32  ? 881 ALA A C     1 
ATOM   6323 O O     . ALA A 1 881 ? 128.708 156.448 149.512 1.00 57.82  ? 881 ALA A O     1 
ATOM   6324 C CB    . ALA A 1 881 ? 130.989 155.182 147.844 1.00 54.25  ? 881 ALA A CB    1 
ATOM   6325 N N     . GLU A 1 882 ? 128.970 154.415 150.446 1.00 50.63  ? 882 GLU A N     1 
ATOM   6326 C CA    . GLU A 1 882 ? 127.595 154.356 150.926 1.00 51.36  ? 882 GLU A CA    1 
ATOM   6327 C C     . GLU A 1 882 ? 127.512 153.915 152.384 1.00 56.00  ? 882 GLU A C     1 
ATOM   6328 O O     . GLU A 1 882 ? 126.484 153.368 152.800 1.00 58.85  ? 882 GLU A O     1 
ATOM   6329 C CB    . GLU A 1 882 ? 126.746 153.440 150.037 1.00 55.56  ? 882 GLU A CB    1 
ATOM   6330 C CG    . GLU A 1 882 ? 127.231 152.008 149.931 1.00 65.44  ? 882 GLU A CG    1 
ATOM   6331 C CD    . GLU A 1 882 ? 126.442 151.211 148.907 1.00 76.71  ? 882 GLU A CD    1 
ATOM   6332 O OE1   . GLU A 1 882 ? 126.393 151.630 147.731 1.00 71.36  ? 882 GLU A OE1   1 
ATOM   6333 O OE2   . GLU A 1 882 ? 125.857 150.173 149.281 1.00 75.73  ? 882 GLU A OE2   1 
ATOM   6334 N N     . ASN A 1 883 ? 128.568 154.149 153.166 1.00 54.53  ? 883 ASN A N     1 
ATOM   6335 C CA    . ASN A 1 883 ? 128.566 153.900 154.609 1.00 49.31  ? 883 ASN A CA    1 
ATOM   6336 C C     . ASN A 1 883 ? 128.252 152.442 154.938 1.00 49.80  ? 883 ASN A C     1 
ATOM   6337 O O     . ASN A 1 883 ? 127.449 152.149 155.826 1.00 51.98  ? 883 ASN A O     1 
ATOM   6338 C CB    . ASN A 1 883 ? 127.587 154.828 155.331 1.00 50.83  ? 883 ASN A CB    1 
ATOM   6339 C CG    . ASN A 1 883 ? 127.726 156.271 154.906 1.00 58.91  ? 883 ASN A CG    1 
ATOM   6340 O OD1   . ASN A 1 883 ? 128.768 156.685 154.398 1.00 62.55  ? 883 ASN A OD1   1 
ATOM   6341 N ND2   . ASN A 1 883 ? 126.676 157.051 155.119 1.00 58.54  ? 883 ASN A ND2   1 
ATOM   6342 N N     . TYR A 1 884 ? 128.879 151.517 154.220 1.00 48.09  ? 884 TYR A N     1 
ATOM   6343 C CA    . TYR A 1 884 ? 128.691 150.094 154.465 1.00 53.39  ? 884 TYR A CA    1 
ATOM   6344 C C     . TYR A 1 884 ? 129.938 149.513 155.120 1.00 49.13  ? 884 TYR A C     1 
ATOM   6345 O O     . TYR A 1 884 ? 131.049 149.702 154.624 1.00 48.23  ? 884 TYR A O     1 
ATOM   6346 C CB    . TYR A 1 884 ? 128.377 149.352 153.165 1.00 55.18  ? 884 TYR A CB    1 
ATOM   6347 C CG    . TYR A 1 884 ? 128.098 147.880 153.354 1.00 51.04  ? 884 TYR A CG    1 
ATOM   6348 C CD1   . TYR A 1 884 ? 126.920 147.449 153.946 1.00 47.21  ? 884 TYR A CD1   1 
ATOM   6349 C CD2   . TYR A 1 884 ? 129.009 146.921 152.935 1.00 49.68  ? 884 TYR A CD2   1 
ATOM   6350 C CE1   . TYR A 1 884 ? 126.659 146.108 154.120 1.00 51.59  ? 884 TYR A CE1   1 
ATOM   6351 C CE2   . TYR A 1 884 ? 128.759 145.576 153.106 1.00 50.35  ? 884 TYR A CE2   1 
ATOM   6352 C CZ    . TYR A 1 884 ? 127.579 145.175 153.698 1.00 54.46  ? 884 TYR A CZ    1 
ATOM   6353 O OH    . TYR A 1 884 ? 127.317 143.836 153.872 1.00 61.28  ? 884 TYR A OH    1 
ATOM   6354 N N     . PHE A 1 885 ? 129.750 148.807 156.232 1.00 45.78  ? 885 PHE A N     1 
ATOM   6355 C CA    . PHE A 1 885 ? 130.862 148.154 156.917 1.00 43.66  ? 885 PHE A CA    1 
ATOM   6356 C C     . PHE A 1 885 ? 130.309 146.921 157.616 1.00 48.45  ? 885 PHE A C     1 
ATOM   6357 O O     . PHE A 1 885 ? 129.522 147.048 158.557 1.00 53.03  ? 885 PHE A O     1 
ATOM   6358 C CB    . PHE A 1 885 ? 131.528 149.098 157.913 1.00 46.92  ? 885 PHE A CB    1 
ATOM   6359 C CG    . PHE A 1 885 ? 132.991 148.832 158.114 1.00 52.99  ? 885 PHE A CG    1 
ATOM   6360 C CD1   . PHE A 1 885 ? 133.417 147.694 158.775 1.00 52.13  ? 885 PHE A CD1   1 
ATOM   6361 C CD2   . PHE A 1 885 ? 133.941 149.724 157.645 1.00 57.42  ? 885 PHE A CD2   1 
ATOM   6362 C CE1   . PHE A 1 885 ? 134.762 147.447 158.960 1.00 51.18  ? 885 PHE A CE1   1 
ATOM   6363 C CE2   . PHE A 1 885 ? 135.288 149.484 157.829 1.00 57.68  ? 885 PHE A CE2   1 
ATOM   6364 C CZ    . PHE A 1 885 ? 135.699 148.344 158.488 1.00 54.44  ? 885 PHE A CZ    1 
ATOM   6365 N N     . SER A 1 886 ? 130.715 145.737 157.164 1.00 45.85  ? 886 SER A N     1 
ATOM   6366 C CA    . SER A 1 886 ? 130.210 144.491 157.718 1.00 43.78  ? 886 SER A CA    1 
ATOM   6367 C C     . SER A 1 886 ? 131.374 143.608 158.131 1.00 40.91  ? 886 SER A C     1 
ATOM   6368 O O     . SER A 1 886 ? 132.278 143.348 157.330 1.00 40.18  ? 886 SER A O     1 
ATOM   6369 C CB    . SER A 1 886 ? 129.326 143.754 156.709 1.00 45.27  ? 886 SER A CB    1 
ATOM   6370 O OG    . SER A 1 886 ? 128.820 142.552 157.262 1.00 44.22  ? 886 SER A OG    1 
ATOM   6371 N N     . ARG A 1 887 ? 131.350 143.154 159.381 1.00 37.03  ? 887 ARG A N     1 
ATOM   6372 C CA    . ARG A 1 887 ? 132.248 142.116 159.869 1.00 33.79  ? 887 ARG A CA    1 
ATOM   6373 C C     . ARG A 1 887 ? 131.398 140.929 160.290 1.00 32.93  ? 887 ARG A C     1 
ATOM   6374 O O     . ARG A 1 887 ? 130.557 141.052 161.186 1.00 34.27  ? 887 ARG A O     1 
ATOM   6375 C CB    . ARG A 1 887 ? 133.099 142.612 161.037 1.00 36.38  ? 887 ARG A CB    1 
ATOM   6376 C CG    . ARG A 1 887 ? 133.969 143.810 160.718 1.00 43.77  ? 887 ARG A CG    1 
ATOM   6377 C CD    . ARG A 1 887 ? 134.879 144.131 161.888 1.00 40.52  ? 887 ARG A CD    1 
ATOM   6378 N NE    . ARG A 1 887 ? 135.922 143.126 162.053 1.00 35.52  ? 887 ARG A NE    1 
ATOM   6379 C CZ    . ARG A 1 887 ? 136.646 142.970 163.152 1.00 34.37  ? 887 ARG A CZ    1 
ATOM   6380 N NH1   . ARG A 1 887 ? 136.443 143.714 164.226 1.00 35.12  ? 887 ARG A NH1   1 
ATOM   6381 N NH2   . ARG A 1 887 ? 137.595 142.040 163.177 1.00 33.62  ? 887 ARG A NH2   1 
ATOM   6382 N N     . TRP A 1 888 ? 131.620 139.786 159.648 1.00 33.33  ? 888 TRP A N     1 
ATOM   6383 C CA    . TRP A 1 888 ? 130.840 138.583 159.891 1.00 31.79  ? 888 TRP A CA    1 
ATOM   6384 C C     . TRP A 1 888 ? 131.771 137.428 160.224 1.00 28.55  ? 888 TRP A C     1 
ATOM   6385 O O     . TRP A 1 888 ? 132.930 137.405 159.804 1.00 28.22  ? 888 TRP A O     1 
ATOM   6386 C CB    . TRP A 1 888 ? 129.973 138.227 158.673 1.00 29.27  ? 888 TRP A CB    1 
ATOM   6387 C CG    . TRP A 1 888 ? 130.767 137.811 157.473 1.00 25.89  ? 888 TRP A CG    1 
ATOM   6388 C CD1   . TRP A 1 888 ? 131.117 136.543 157.124 1.00 25.62  ? 888 TRP A CD1   1 
ATOM   6389 C CD2   . TRP A 1 888 ? 131.304 138.668 156.459 1.00 25.26  ? 888 TRP A CD2   1 
ATOM   6390 N NE1   . TRP A 1 888 ? 131.841 136.554 155.959 1.00 26.83  ? 888 TRP A NE1   1 
ATOM   6391 C CE2   . TRP A 1 888 ? 131.970 137.848 155.531 1.00 25.12  ? 888 TRP A CE2   1 
ATOM   6392 C CE3   . TRP A 1 888 ? 131.287 140.049 156.247 1.00 29.62  ? 888 TRP A CE3   1 
ATOM   6393 C CZ2   . TRP A 1 888 ? 132.616 138.361 154.412 1.00 24.69  ? 888 TRP A CZ2   1 
ATOM   6394 C CZ3   . TRP A 1 888 ? 131.928 140.555 155.137 1.00 32.51  ? 888 TRP A CZ3   1 
ATOM   6395 C CH2   . TRP A 1 888 ? 132.588 139.714 154.236 1.00 31.14  ? 888 TRP A CH2   1 
ATOM   6396 N N     . VAL A 1 889 ? 131.256 136.472 160.990 1.00 23.02  ? 889 VAL A N     1 
ATOM   6397 C CA    . VAL A 1 889 ? 132.013 135.276 161.354 1.00 22.59  ? 889 VAL A CA    1 
ATOM   6398 C C     . VAL A 1 889 ? 132.043 134.333 160.157 1.00 24.94  ? 889 VAL A C     1 
ATOM   6399 O O     . VAL A 1 889 ? 130.980 133.942 159.653 1.00 31.67  ? 889 VAL A O     1 
ATOM   6400 C CB    . VAL A 1 889 ? 131.409 134.587 162.588 1.00 23.38  ? 889 VAL A CB    1 
ATOM   6401 C CG1   . VAL A 1 889 ? 132.209 133.345 162.946 1.00 26.60  ? 889 VAL A CG1   1 
ATOM   6402 C CG2   . VAL A 1 889 ? 131.354 135.547 163.760 1.00 24.15  ? 889 VAL A CG2   1 
ATOM   6403 N N     . PRO A 1 890 ? 133.218 133.950 159.663 1.00 21.14  ? 890 PRO A N     1 
ATOM   6404 C CA    . PRO A 1 890 ? 133.273 133.027 158.525 1.00 24.43  ? 890 PRO A CA    1 
ATOM   6405 C C     . PRO A 1 890 ? 132.767 131.644 158.897 1.00 34.35  ? 890 PRO A C     1 
ATOM   6406 O O     . PRO A 1 890 ? 132.880 131.201 160.042 1.00 39.35  ? 890 PRO A O     1 
ATOM   6407 C CB    . PRO A 1 890 ? 134.761 132.997 158.164 1.00 25.29  ? 890 PRO A CB    1 
ATOM   6408 C CG    . PRO A 1 890 ? 135.454 133.362 159.420 1.00 25.64  ? 890 PRO A CG    1 
ATOM   6409 C CD    . PRO A 1 890 ? 134.560 134.340 160.121 1.00 26.32  ? 890 PRO A CD    1 
ATOM   6410 N N     . LYS A 1 891 ? 132.203 130.961 157.906 1.00 41.99  ? 891 LYS A N     1 
ATOM   6411 C CA    . LYS A 1 891 ? 131.624 129.645 158.120 1.00 43.47  ? 891 LYS A CA    1 
ATOM   6412 C C     . LYS A 1 891 ? 132.711 128.582 158.244 1.00 43.91  ? 891 LYS A C     1 
ATOM   6413 O O     . LYS A 1 891 ? 133.844 128.750 157.786 1.00 41.36  ? 891 LYS A O     1 
ATOM   6414 C CB    . LYS A 1 891 ? 130.676 129.271 156.980 1.00 50.96  ? 891 LYS A CB    1 
ATOM   6415 C CG    . LYS A 1 891 ? 129.327 129.973 157.010 1.00 59.42  ? 891 LYS A CG    1 
ATOM   6416 C CD    . LYS A 1 891 ? 129.360 131.292 156.258 1.00 63.05  ? 891 LYS A CD    1 
ATOM   6417 C CE    . LYS A 1 891 ? 127.967 131.890 156.146 1.00 67.29  ? 891 LYS A CE    1 
ATOM   6418 N NZ    . LYS A 1 891 ? 127.958 133.130 155.323 1.00 61.59  ? 891 LYS A NZ    1 
ATOM   6419 N N     . ALA A 1 892 ? 132.343 127.473 158.879 1.00 41.51  ? 892 ALA A N     1 
ATOM   6420 C CA    . ALA A 1 892 ? 133.222 126.321 158.944 1.00 31.73  ? 892 ALA A CA    1 
ATOM   6421 C C     . ALA A 1 892 ? 133.357 125.694 157.558 1.00 34.19  ? 892 ALA A C     1 
ATOM   6422 O O     . ALA A 1 892 ? 132.476 125.857 156.710 1.00 46.38  ? 892 ALA A O     1 
ATOM   6423 C CB    . ALA A 1 892 ? 132.679 125.294 159.934 1.00 32.78  ? 892 ALA A CB    1 
ATOM   6424 N N     . PRO A 1 893 ? 134.457 124.990 157.295 1.00 31.42  ? 893 PRO A N     1 
ATOM   6425 C CA    . PRO A 1 893 ? 134.606 124.336 155.990 1.00 35.85  ? 893 PRO A CA    1 
ATOM   6426 C C     . PRO A 1 893 ? 133.498 123.322 155.751 1.00 48.29  ? 893 PRO A C     1 
ATOM   6427 O O     . PRO A 1 893 ? 133.076 122.607 156.662 1.00 49.02  ? 893 PRO A O     1 
ATOM   6428 C CB    . PRO A 1 893 ? 135.981 123.664 156.084 1.00 34.77  ? 893 PRO A CB    1 
ATOM   6429 C CG    . PRO A 1 893 ? 136.253 123.548 157.541 1.00 35.27  ? 893 PRO A CG    1 
ATOM   6430 C CD    . PRO A 1 893 ? 135.619 124.747 158.164 1.00 34.04  ? 893 PRO A CD    1 
ATOM   6431 N N     . ASP A 1 894 ? 133.025 123.271 154.509 1.00 54.18  ? 894 ASP A N     1 
ATOM   6432 C CA    . ASP A 1 894 ? 131.924 122.384 154.162 1.00 51.40  ? 894 ASP A CA    1 
ATOM   6433 C C     . ASP A 1 894 ? 132.373 120.931 154.228 1.00 47.80  ? 894 ASP A C     1 
ATOM   6434 O O     . ASP A 1 894 ? 133.430 120.571 153.700 1.00 45.59  ? 894 ASP A O     1 
ATOM   6435 C CB    . ASP A 1 894 ? 131.399 122.713 152.766 1.00 59.05  ? 894 ASP A CB    1 
ATOM   6436 C CG    . ASP A 1 894 ? 130.811 124.108 152.678 1.00 76.25  ? 894 ASP A CG    1 
ATOM   6437 O OD1   . ASP A 1 894 ? 130.157 124.541 153.649 1.00 75.68  ? 894 ASP A OD1   1 
ATOM   6438 O OD2   . ASP A 1 894 ? 131.006 124.771 151.637 1.00 88.57  ? 894 ASP A OD2   1 
ATOM   6439 N N     . ILE A 1 895 ? 131.567 120.096 154.877 1.00 41.01  ? 895 ILE A N     1 
ATOM   6440 C CA    . ILE A 1 895 ? 131.878 118.678 155.016 1.00 37.29  ? 895 ILE A CA    1 
ATOM   6441 C C     . ILE A 1 895 ? 131.456 117.973 153.733 1.00 40.78  ? 895 ILE A C     1 
ATOM   6442 O O     . ILE A 1 895 ? 130.266 117.888 153.420 1.00 43.65  ? 895 ILE A O     1 
ATOM   6443 C CB    . ILE A 1 895 ? 131.185 118.066 156.238 1.00 41.10  ? 895 ILE A CB    1 
ATOM   6444 C CG1   . ILE A 1 895 ? 131.855 118.539 157.529 1.00 47.85  ? 895 ILE A CG1   1 
ATOM   6445 C CG2   . ILE A 1 895 ? 131.204 116.545 156.160 1.00 40.73  ? 895 ILE A CG2   1 
ATOM   6446 C CD1   . ILE A 1 895 ? 133.191 117.884 157.796 1.00 50.09  ? 895 ILE A CD1   1 
ATOM   6447 N N     . GLN A 1 896 ? 132.432 117.479 152.981 1.00 38.31  ? 896 GLN A N     1 
ATOM   6448 C CA    . GLN A 1 896 ? 132.164 116.642 151.823 1.00 33.29  ? 896 GLN A CA    1 
ATOM   6449 C C     . GLN A 1 896 ? 132.061 115.195 152.279 1.00 39.08  ? 896 GLN A C     1 
ATOM   6450 O O     . GLN A 1 896 ? 132.961 114.684 152.956 1.00 42.54  ? 896 GLN A O     1 
ATOM   6451 C CB    . GLN A 1 896 ? 133.260 116.794 150.770 1.00 29.52  ? 896 GLN A CB    1 
ATOM   6452 C CG    . GLN A 1 896 ? 133.441 118.211 150.268 1.00 31.65  ? 896 GLN A CG    1 
ATOM   6453 C CD    . GLN A 1 896 ? 134.320 118.284 149.041 1.00 34.19  ? 896 GLN A CD    1 
ATOM   6454 O OE1   . GLN A 1 896 ? 134.138 117.527 148.089 1.00 38.08  ? 896 GLN A OE1   1 
ATOM   6455 N NE2   . GLN A 1 896 ? 135.285 119.196 149.057 1.00 35.96  ? 896 GLN A NE2   1 
ATOM   6456 N N     . LYS A 1 897 ? 130.961 114.544 151.910 1.00 39.92  ? 897 LYS A N     1 
ATOM   6457 C CA    . LYS A 1 897 ? 130.672 113.174 152.307 1.00 34.41  ? 897 LYS A CA    1 
ATOM   6458 C C     . LYS A 1 897 ? 130.603 112.295 151.069 1.00 33.19  ? 897 LYS A C     1 
ATOM   6459 O O     . LYS A 1 897 ? 129.951 112.652 150.083 1.00 39.29  ? 897 LYS A O     1 
ATOM   6460 C CB    . LYS A 1 897 ? 129.358 113.092 153.086 1.00 37.55  ? 897 LYS A CB    1 
ATOM   6461 C CG    . LYS A 1 897 ? 128.979 111.684 153.508 1.00 41.45  ? 897 LYS A CG    1 
ATOM   6462 C CD    . LYS A 1 897 ? 127.625 111.656 154.195 1.00 46.55  ? 897 LYS A CD    1 
ATOM   6463 C CE    . LYS A 1 897 ? 127.271 110.249 154.647 1.00 48.21  ? 897 LYS A CE    1 
ATOM   6464 N NZ    . LYS A 1 897 ? 127.199 109.302 153.502 1.00 45.71  ? 897 LYS A NZ    1 
ATOM   6465 N N     . PHE A 1 898 ? 131.274 111.148 151.127 1.00 29.76  ? 898 PHE A N     1 
ATOM   6466 C CA    . PHE A 1 898 ? 131.246 110.160 150.050 1.00 31.72  ? 898 PHE A CA    1 
ATOM   6467 C C     . PHE A 1 898 ? 131.266 108.785 150.708 1.00 33.96  ? 898 PHE A C     1 
ATOM   6468 O O     . PHE A 1 898 ? 132.327 108.305 151.118 1.00 37.66  ? 898 PHE A O     1 
ATOM   6469 C CB    . PHE A 1 898 ? 132.417 110.346 149.095 1.00 28.07  ? 898 PHE A CB    1 
ATOM   6470 C CG    . PHE A 1 898 ? 132.452 109.349 147.978 1.00 28.54  ? 898 PHE A CG    1 
ATOM   6471 C CD1   . PHE A 1 898 ? 131.490 109.369 146.985 1.00 34.73  ? 898 PHE A CD1   1 
ATOM   6472 C CD2   . PHE A 1 898 ? 133.453 108.400 147.911 1.00 23.36  ? 898 PHE A CD2   1 
ATOM   6473 C CE1   . PHE A 1 898 ? 131.523 108.453 145.954 1.00 33.85  ? 898 PHE A CE1   1 
ATOM   6474 C CE2   . PHE A 1 898 ? 133.489 107.486 146.883 1.00 25.16  ? 898 PHE A CE2   1 
ATOM   6475 C CZ    . PHE A 1 898 ? 132.526 107.511 145.905 1.00 28.87  ? 898 PHE A CZ    1 
ATOM   6476 N N     . HIS A 1 899 ? 130.091 108.162 150.802 1.00 29.96  ? 899 HIS A N     1 
ATOM   6477 C CA    . HIS A 1 899 ? 129.911 106.907 151.520 1.00 32.29  ? 899 HIS A CA    1 
ATOM   6478 C C     . HIS A 1 899 ? 130.370 107.046 152.967 1.00 43.33  ? 899 HIS A C     1 
ATOM   6479 O O     . HIS A 1 899 ? 129.754 107.780 153.746 1.00 48.06  ? 899 HIS A O     1 
ATOM   6480 C CB    . HIS A 1 899 ? 130.649 105.768 150.814 1.00 34.84  ? 899 HIS A CB    1 
ATOM   6481 C CG    . HIS A 1 899 ? 130.139 105.487 149.435 1.00 39.23  ? 899 HIS A CG    1 
ATOM   6482 N ND1   . HIS A 1 899 ? 130.886 105.725 148.302 1.00 46.46  ? 899 HIS A ND1   1 
ATOM   6483 C CD2   . HIS A 1 899 ? 128.953 104.994 149.007 1.00 40.45  ? 899 HIS A CD2   1 
ATOM   6484 C CE1   . HIS A 1 899 ? 130.184 105.385 147.235 1.00 46.05  ? 899 HIS A CE1   1 
ATOM   6485 N NE2   . HIS A 1 899 ? 129.007 104.939 147.636 1.00 42.00  ? 899 HIS A NE2   1 
ATOM   6486 N N     . HIS A 1 900 ? 131.441 106.351 153.342 1.00 40.89  ? 900 HIS A N     1 
ATOM   6487 C CA    . HIS A 1 900 ? 131.969 106.425 154.698 1.00 36.37  ? 900 HIS A CA    1 
ATOM   6488 C C     . HIS A 1 900 ? 133.056 107.478 154.860 1.00 38.08  ? 900 HIS A C     1 
ATOM   6489 O O     . HIS A 1 900 ? 133.553 107.667 155.974 1.00 44.12  ? 900 HIS A O     1 
ATOM   6490 C CB    . HIS A 1 900 ? 132.508 105.059 155.133 1.00 41.32  ? 900 HIS A CB    1 
ATOM   6491 C CG    . HIS A 1 900 ? 133.472 104.451 154.164 1.00 46.76  ? 900 HIS A CG    1 
ATOM   6492 N ND1   . HIS A 1 900 ? 133.066 103.830 153.003 1.00 50.81  ? 900 HIS A ND1   1 
ATOM   6493 C CD2   . HIS A 1 900 ? 134.822 104.359 154.188 1.00 45.71  ? 900 HIS A CD2   1 
ATOM   6494 C CE1   . HIS A 1 900 ? 134.125 103.386 152.350 1.00 46.44  ? 900 HIS A CE1   1 
ATOM   6495 N NE2   . HIS A 1 900 ? 135.203 103.696 153.047 1.00 43.34  ? 900 HIS A NE2   1 
ATOM   6496 N N     . LEU A 1 901 ? 133.432 108.165 153.786 1.00 37.54  ? 901 LEU A N     1 
ATOM   6497 C CA    . LEU A 1 901 ? 134.465 109.190 153.835 1.00 35.79  ? 901 LEU A CA    1 
ATOM   6498 C C     . LEU A 1 901 ? 133.853 110.551 154.130 1.00 39.51  ? 901 LEU A C     1 
ATOM   6499 O O     . LEU A 1 901 ? 132.826 110.917 153.550 1.00 45.43  ? 901 LEU A O     1 
ATOM   6500 C CB    . LEU A 1 901 ? 135.227 109.253 152.514 1.00 26.85  ? 901 LEU A CB    1 
ATOM   6501 C CG    . LEU A 1 901 ? 136.514 108.455 152.375 1.00 28.92  ? 901 LEU A CG    1 
ATOM   6502 C CD1   . LEU A 1 901 ? 136.228 106.968 152.387 1.00 38.70  ? 901 LEU A CD1   1 
ATOM   6503 C CD2   . LEU A 1 901 ? 137.223 108.867 151.100 1.00 29.36  ? 901 LEU A CD2   1 
ATOM   6504 N N     . LYS A 1 902 ? 134.489 111.298 155.025 1.00 33.11  ? 902 LYS A N     1 
ATOM   6505 C CA    . LYS A 1 902 ? 134.164 112.695 155.267 1.00 29.87  ? 902 LYS A CA    1 
ATOM   6506 C C     . LYS A 1 902 ? 135.460 113.489 155.234 1.00 30.79  ? 902 LYS A C     1 
ATOM   6507 O O     . LYS A 1 902 ? 136.451 113.084 155.850 1.00 32.94  ? 902 LYS A O     1 
ATOM   6508 C CB    . LYS A 1 902 ? 133.448 112.879 156.609 1.00 38.46  ? 902 LYS A CB    1 
ATOM   6509 C CG    . LYS A 1 902 ? 132.137 112.116 156.735 1.00 40.70  ? 902 LYS A CG    1 
ATOM   6510 C CD    . LYS A 1 902 ? 131.459 112.394 158.070 1.00 50.94  ? 902 LYS A CD    1 
ATOM   6511 C CE    . LYS A 1 902 ? 130.068 111.780 158.130 1.00 54.64  ? 902 LYS A CE    1 
ATOM   6512 N NZ    . LYS A 1 902 ? 129.172 112.337 157.079 1.00 51.33  ? 902 LYS A NZ    1 
ATOM   6513 N N     . TRP A 1 903 ? 135.467 114.599 154.501 1.00 30.04  ? 903 TRP A N     1 
ATOM   6514 C CA    . TRP A 1 903 ? 136.665 115.425 154.446 1.00 28.14  ? 903 TRP A CA    1 
ATOM   6515 C C     . TRP A 1 903 ? 136.291 116.864 154.126 1.00 30.51  ? 903 TRP A C     1 
ATOM   6516 O O     . TRP A 1 903 ? 135.244 117.134 153.534 1.00 33.10  ? 903 TRP A O     1 
ATOM   6517 C CB    . TRP A 1 903 ? 137.677 114.894 153.420 1.00 29.64  ? 903 TRP A CB    1 
ATOM   6518 C CG    . TRP A 1 903 ? 137.351 115.214 151.993 1.00 29.79  ? 903 TRP A CG    1 
ATOM   6519 C CD1   . TRP A 1 903 ? 137.959 116.144 151.203 1.00 24.33  ? 903 TRP A CD1   1 
ATOM   6520 C CD2   . TRP A 1 903 ? 136.346 114.596 151.183 1.00 31.82  ? 903 TRP A CD2   1 
ATOM   6521 N NE1   . TRP A 1 903 ? 137.395 116.145 149.953 1.00 23.82  ? 903 TRP A NE1   1 
ATOM   6522 C CE2   . TRP A 1 903 ? 136.401 115.204 149.914 1.00 29.09  ? 903 TRP A CE2   1 
ATOM   6523 C CE3   . TRP A 1 903 ? 135.404 113.589 151.406 1.00 29.08  ? 903 TRP A CE3   1 
ATOM   6524 C CZ2   . TRP A 1 903 ? 135.549 114.840 148.877 1.00 30.95  ? 903 TRP A CZ2   1 
ATOM   6525 C CZ3   . TRP A 1 903 ? 134.561 113.232 150.377 1.00 28.02  ? 903 TRP A CZ3   1 
ATOM   6526 C CH2   . TRP A 1 903 ? 134.638 113.854 149.129 1.00 32.14  ? 903 TRP A CH2   1 
ATOM   6527 N N     . THR A 1 904 ? 137.161 117.783 154.532 1.00 28.80  ? 904 THR A N     1 
ATOM   6528 C CA    . THR A 1 904 ? 137.023 119.209 154.293 1.00 25.45  ? 904 THR A CA    1 
ATOM   6529 C C     . THR A 1 904 ? 138.057 119.665 153.266 1.00 24.05  ? 904 THR A C     1 
ATOM   6530 O O     . THR A 1 904 ? 138.781 118.858 152.677 1.00 27.28  ? 904 THR A O     1 
ATOM   6531 C CB    . THR A 1 904 ? 137.159 119.983 155.604 1.00 32.32  ? 904 THR A CB    1 
ATOM   6532 O OG1   . THR A 1 904 ? 138.305 119.512 156.323 1.00 38.85  ? 904 THR A OG1   1 
ATOM   6533 C CG2   . THR A 1 904 ? 135.923 119.804 156.459 1.00 37.49  ? 904 THR A CG2   1 
ATOM   6534 N N     . CYS A 1 905 ? 138.123 120.979 153.054 1.00 22.96  ? 905 CYS A N     1 
ATOM   6535 C CA    . CYS A 1 905 ? 139.058 121.558 152.099 1.00 27.18  ? 905 CYS A CA    1 
ATOM   6536 C C     . CYS A 1 905 ? 140.506 121.496 152.565 1.00 32.76  ? 905 CYS A C     1 
ATOM   6537 O O     . CYS A 1 905 ? 141.403 121.805 151.774 1.00 34.13  ? 905 CYS A O     1 
ATOM   6538 C CB    . CYS A 1 905 ? 138.671 123.008 151.815 1.00 33.48  ? 905 CYS A CB    1 
ATOM   6539 S SG    . CYS A 1 905 ? 138.327 123.973 153.300 1.00 45.39  ? 905 CYS A SG    1 
ATOM   6540 N N     . TRP A 1 906 ? 140.757 121.117 153.818 1.00 31.99  ? 906 TRP A N     1 
ATOM   6541 C CA    . TRP A 1 906 ? 142.111 121.076 154.352 1.00 25.29  ? 906 TRP A CA    1 
ATOM   6542 C C     . TRP A 1 906 ? 142.695 119.676 154.436 1.00 24.77  ? 906 TRP A C     1 
ATOM   6543 O O     . TRP A 1 906 ? 143.922 119.541 154.495 1.00 33.64  ? 906 TRP A O     1 
ATOM   6544 C CB    . TRP A 1 906 ? 142.152 121.689 155.756 1.00 28.79  ? 906 TRP A CB    1 
ATOM   6545 C CG    . TRP A 1 906 ? 141.485 123.011 155.870 1.00 28.86  ? 906 TRP A CG    1 
ATOM   6546 C CD1   . TRP A 1 906 ? 140.212 123.247 156.280 1.00 23.92  ? 906 TRP A CD1   1 
ATOM   6547 C CD2   . TRP A 1 906 ? 142.057 124.291 155.576 1.00 27.92  ? 906 TRP A CD2   1 
ATOM   6548 N NE1   . TRP A 1 906 ? 139.950 124.589 156.261 1.00 22.28  ? 906 TRP A NE1   1 
ATOM   6549 C CE2   . TRP A 1 906 ? 141.067 125.255 155.832 1.00 26.30  ? 906 TRP A CE2   1 
ATOM   6550 C CE3   . TRP A 1 906 ? 143.308 124.713 155.122 1.00 24.29  ? 906 TRP A CE3   1 
ATOM   6551 C CZ2   . TRP A 1 906 ? 141.289 126.616 155.650 1.00 29.92  ? 906 TRP A CZ2   1 
ATOM   6552 C CZ3   . TRP A 1 906 ? 143.524 126.062 154.939 1.00 22.25  ? 906 TRP A CZ3   1 
ATOM   6553 C CH2   . TRP A 1 906 ? 142.521 126.998 155.202 1.00 26.41  ? 906 TRP A CH2   1 
ATOM   6554 N N     . ASP A 1 907 ? 141.861 118.642 154.448 1.00 21.49  ? 907 ASP A N     1 
ATOM   6555 C CA    . ASP A 1 907 ? 142.321 117.310 154.797 1.00 20.43  ? 907 ASP A CA    1 
ATOM   6556 C C     . ASP A 1 907 ? 143.276 116.765 153.740 1.00 20.28  ? 907 ASP A C     1 
ATOM   6557 O O     . ASP A 1 907 ? 143.370 117.268 152.617 1.00 21.76  ? 907 ASP A O     1 
ATOM   6558 C CB    . ASP A 1 907 ? 141.136 116.368 154.984 1.00 27.12  ? 907 ASP A CB    1 
ATOM   6559 C CG    . ASP A 1 907 ? 140.368 116.649 156.257 1.00 41.03  ? 907 ASP A CG    1 
ATOM   6560 O OD1   . ASP A 1 907 ? 140.824 117.499 157.050 1.00 45.94  ? 907 ASP A OD1   1 
ATOM   6561 O OD2   . ASP A 1 907 ? 139.310 116.020 156.467 1.00 42.72  ? 907 ASP A OD2   1 
ATOM   6562 N N     . ARG A 1 908 ? 144.001 115.719 154.125 1.00 22.52  ? 908 ARG A N     1 
ATOM   6563 C CA    . ARG A 1 908 ? 144.973 115.084 153.249 1.00 21.01  ? 908 ARG A CA    1 
ATOM   6564 C C     . ARG A 1 908 ? 145.313 113.715 153.815 1.00 26.12  ? 908 ARG A C     1 
ATOM   6565 O O     . ARG A 1 908 ? 144.961 113.382 154.949 1.00 36.76  ? 908 ARG A O     1 
ATOM   6566 C CB    . ARG A 1 908 ? 146.233 115.932 153.112 1.00 23.24  ? 908 ARG A CB    1 
ATOM   6567 C CG    . ARG A 1 908 ? 147.101 115.929 154.357 1.00 27.42  ? 908 ARG A CG    1 
ATOM   6568 C CD    . ARG A 1 908 ? 147.887 117.211 154.445 1.00 23.59  ? 908 ARG A CD    1 
ATOM   6569 N NE    . ARG A 1 908 ? 147.013 118.356 154.234 1.00 17.95  ? 908 ARG A NE    1 
ATOM   6570 C CZ    . ARG A 1 908 ? 147.433 119.606 154.128 1.00 18.39  ? 908 ARG A CZ    1 
ATOM   6571 N NH1   . ARG A 1 908 ? 148.713 119.913 154.227 1.00 21.75  ? 908 ARG A NH1   1 
ATOM   6572 N NH2   . ARG A 1 908 ? 146.545 120.571 153.913 1.00 21.99  ? 908 ARG A NH2   1 
ATOM   6573 N N     . LEU A 1 909 ? 146.006 112.924 153.004 1.00 23.75  ? 909 LEU A N     1 
ATOM   6574 C CA    . LEU A 1 909 ? 146.541 111.636 153.415 1.00 26.76  ? 909 LEU A CA    1 
ATOM   6575 C C     . LEU A 1 909 ? 148.053 111.678 153.272 1.00 27.27  ? 909 LEU A C     1 
ATOM   6576 O O     . LEU A 1 909 ? 148.564 112.044 152.211 1.00 29.82  ? 909 LEU A O     1 
ATOM   6577 C CB    . LEU A 1 909 ? 145.961 110.497 152.571 1.00 24.22  ? 909 LEU A CB    1 
ATOM   6578 C CG    . LEU A 1 909 ? 144.449 110.291 152.580 1.00 24.33  ? 909 LEU A CG    1 
ATOM   6579 C CD1   . LEU A 1 909 ? 144.071 109.156 151.652 1.00 29.69  ? 909 LEU A CD1   1 
ATOM   6580 C CD2   . LEU A 1 909 ? 143.957 110.018 153.990 1.00 31.27  ? 909 LEU A CD2   1 
ATOM   6581 N N     . GLU A 1 910 ? 148.766 111.295 154.324 1.00 25.61  ? 910 GLU A N     1 
ATOM   6582 C CA    . GLU A 1 910 ? 150.222 111.329 154.327 1.00 28.29  ? 910 GLU A CA    1 
ATOM   6583 C C     . GLU A 1 910 ? 150.749 109.902 154.355 1.00 29.96  ? 910 GLU A C     1 
ATOM   6584 O O     . GLU A 1 910 ? 150.418 109.132 155.263 1.00 38.16  ? 910 GLU A O     1 
ATOM   6585 C CB    . GLU A 1 910 ? 150.747 112.129 155.519 1.00 38.58  ? 910 GLU A CB    1 
ATOM   6586 C CG    . GLU A 1 910 ? 152.220 112.495 155.422 1.00 48.56  ? 910 GLU A CG    1 
ATOM   6587 C CD    . GLU A 1 910 ? 152.616 113.578 156.407 1.00 60.18  ? 910 GLU A CD    1 
ATOM   6588 O OE1   . GLU A 1 910 ? 151.810 113.885 157.310 1.00 68.93  ? 910 GLU A OE1   1 
ATOM   6589 O OE2   . GLU A 1 910 ? 153.730 114.126 156.275 1.00 58.95  ? 910 GLU A OE2   1 
ATOM   6590 N N     . VAL A 1 911 ? 151.563 109.554 153.363 1.00 27.79  ? 911 VAL A N     1 
ATOM   6591 C CA    . VAL A 1 911 ? 152.102 108.203 153.231 1.00 29.90  ? 911 VAL A CA    1 
ATOM   6592 C C     . VAL A 1 911 ? 153.605 108.281 152.996 1.00 29.08  ? 911 VAL A C     1 
ATOM   6593 O O     . VAL A 1 911 ? 154.051 108.985 152.080 1.00 34.71  ? 911 VAL A O     1 
ATOM   6594 C CB    . VAL A 1 911 ? 151.407 107.433 152.097 1.00 30.94  ? 911 VAL A CB    1 
ATOM   6595 C CG1   . VAL A 1 911 ? 152.109 106.109 151.846 1.00 32.84  ? 911 VAL A CG1   1 
ATOM   6596 C CG2   . VAL A 1 911 ? 149.947 107.203 152.431 1.00 32.63  ? 911 VAL A CG2   1 
ATOM   6597 N N     . PRO A 1 912 ? 154.416 107.584 153.784 1.00 29.96  ? 912 PRO A N     1 
ATOM   6598 C CA    . PRO A 1 912 ? 155.864 107.621 153.571 1.00 29.94  ? 912 PRO A CA    1 
ATOM   6599 C C     . PRO A 1 912 ? 156.300 106.732 152.419 1.00 35.37  ? 912 PRO A C     1 
ATOM   6600 O O     . PRO A 1 912 ? 155.739 105.662 152.173 1.00 42.13  ? 912 PRO A O     1 
ATOM   6601 C CB    . PRO A 1 912 ? 156.422 107.106 154.902 1.00 30.47  ? 912 PRO A CB    1 
ATOM   6602 C CG    . PRO A 1 912 ? 155.363 106.191 155.402 1.00 30.39  ? 912 PRO A CG    1 
ATOM   6603 C CD    . PRO A 1 912 ? 154.052 106.792 154.971 1.00 32.55  ? 912 PRO A CD    1 
ATOM   6604 N N     . ALA A 1 913 ? 157.325 107.200 151.705 1.00 36.76  ? 913 ALA A N     1 
ATOM   6605 C CA    . ALA A 1 913 ? 157.923 106.390 150.650 1.00 40.03  ? 913 ALA A CA    1 
ATOM   6606 C C     . ALA A 1 913 ? 158.661 105.188 151.226 1.00 46.17  ? 913 ALA A C     1 
ATOM   6607 O O     . ALA A 1 913 ? 158.648 104.102 150.636 1.00 49.19  ? 913 ALA A O     1 
ATOM   6608 C CB    . ALA A 1 913 ? 158.863 107.244 149.802 1.00 44.51  ? 913 ALA A CB    1 
ATOM   6609 N N     . GLY A 1 914 ? 159.307 105.361 152.374 1.00 47.76  ? 914 GLY A N     1 
ATOM   6610 C CA    . GLY A 1 914 ? 160.065 104.299 153.000 1.00 44.74  ? 914 GLY A CA    1 
ATOM   6611 C C     . GLY A 1 914 ? 161.535 104.339 152.620 1.00 48.31  ? 914 GLY A C     1 
ATOM   6612 O O     . GLY A 1 914 ? 161.934 104.921 151.612 1.00 53.01  ? 914 GLY A O     1 
ATOM   6613 N N     . GLN A 1 915 ? 162.357 103.712 153.463 1.00 51.57  ? 915 GLN A N     1 
ATOM   6614 C CA    . GLN A 1 915 ? 163.787 103.654 153.171 1.00 57.58  ? 915 GLN A CA    1 
ATOM   6615 C C     . GLN A 1 915 ? 164.055 102.946 151.850 1.00 56.40  ? 915 GLN A C     1 
ATOM   6616 O O     . GLN A 1 915 ? 164.831 103.478 151.038 1.00 57.43  ? 915 GLN A O     1 
ATOM   6617 C CB    . GLN A 1 915 ? 164.537 103.014 154.346 1.00 63.75  ? 915 GLN A CB    1 
ATOM   6618 C CG    . GLN A 1 915 ? 164.316 103.713 155.678 1.00 68.97  ? 915 GLN A CG    1 
ATOM   6619 C CD    . GLN A 1 915 ? 164.808 105.148 155.675 1.00 77.04  ? 915 GLN A CD    1 
ATOM   6620 O OE1   . GLN A 1 915 ? 165.849 105.458 155.096 1.00 83.17  ? 915 GLN A OE1   1 
ATOM   6621 N NE2   . GLN A 1 915 ? 164.055 106.034 156.319 1.00 75.97  ? 915 GLN A NE2   1 
ATOM   6622 N N     . PRO A 1 916 ? 163.469 101.774 151.561 1.00 51.64  ? 916 PRO A N     1 
ATOM   6623 C CA    . PRO A 1 916 ? 163.276 101.405 150.156 1.00 57.81  ? 916 PRO A CA    1 
ATOM   6624 C C     . PRO A 1 916 ? 161.931 101.927 149.677 1.00 56.91  ? 916 PRO A C     1 
ATOM   6625 O O     . PRO A 1 916 ? 160.902 101.651 150.302 1.00 58.91  ? 916 PRO A O     1 
ATOM   6626 C CB    . PRO A 1 916 ? 163.333 99.875  150.182 1.00 59.59  ? 916 PRO A CB    1 
ATOM   6627 C CG    . PRO A 1 916 ? 162.791 99.521  151.520 1.00 50.54  ? 916 PRO A CG    1 
ATOM   6628 C CD    . PRO A 1 916 ? 163.144 100.651 152.462 1.00 48.41  ? 916 PRO A CD    1 
ATOM   6629 N N     . GLU A 1 917 ? 161.916 102.687 148.586 1.00 52.78  ? 917 GLU A N     1 
ATOM   6630 C CA    . GLU A 1 917 ? 160.676 103.311 148.146 1.00 48.12  ? 917 GLU A CA    1 
ATOM   6631 C C     . GLU A 1 917 ? 159.688 102.253 147.674 1.00 47.38  ? 917 GLU A C     1 
ATOM   6632 O O     . GLU A 1 917 ? 160.044 101.349 146.911 1.00 55.45  ? 917 GLU A O     1 
ATOM   6633 C CB    . GLU A 1 917 ? 160.950 104.321 147.035 1.00 52.01  ? 917 GLU A CB    1 
ATOM   6634 C CG    . GLU A 1 917 ? 159.695 104.974 146.484 1.00 56.46  ? 917 GLU A CG    1 
ATOM   6635 C CD    . GLU A 1 917 ? 159.985 106.256 145.738 1.00 61.92  ? 917 GLU A CD    1 
ATOM   6636 O OE1   . GLU A 1 917 ? 160.548 107.188 146.351 1.00 62.11  ? 917 GLU A OE1   1 
ATOM   6637 O OE2   . GLU A 1 917 ? 159.652 106.329 144.538 1.00 61.01  ? 917 GLU A OE2   1 
ATOM   6638 N N     . ARG A 1 918 ? 158.446 102.366 148.133 1.00 40.00  ? 918 ARG A N     1 
ATOM   6639 C CA    . ARG A 1 918 ? 157.430 101.387 147.786 1.00 39.03  ? 918 ARG A CA    1 
ATOM   6640 C C     . ARG A 1 918 ? 157.013 101.530 146.328 1.00 45.99  ? 918 ARG A C     1 
ATOM   6641 O O     . ARG A 1 918 ? 157.110 102.605 145.729 1.00 50.47  ? 918 ARG A O     1 
ATOM   6642 C CB    . ARG A 1 918 ? 156.210 101.540 148.692 1.00 39.76  ? 918 ARG A CB    1 
ATOM   6643 C CG    . ARG A 1 918 ? 155.455 102.844 148.508 1.00 43.45  ? 918 ARG A CG    1 
ATOM   6644 C CD    . ARG A 1 918 ? 154.269 102.943 149.455 1.00 40.26  ? 918 ARG A CD    1 
ATOM   6645 N NE    . ARG A 1 918 ? 154.682 103.183 150.831 1.00 30.81  ? 918 ARG A NE    1 
ATOM   6646 C CZ    . ARG A 1 918 ? 154.809 102.239 151.752 1.00 32.63  ? 918 ARG A CZ    1 
ATOM   6647 N NH1   . ARG A 1 918 ? 154.551 100.971 151.481 1.00 39.44  ? 918 ARG A NH1   1 
ATOM   6648 N NH2   . ARG A 1 918 ? 155.202 102.576 152.977 1.00 35.54  ? 918 ARG A NH2   1 
ATOM   6649 N N     . THR A 1 919 ? 156.551 100.424 145.755 1.00 47.13  ? 919 THR A N     1 
ATOM   6650 C CA    . THR A 1 919 ? 156.018 100.445 144.405 1.00 43.17  ? 919 THR A CA    1 
ATOM   6651 C C     . THR A 1 919 ? 154.642 101.105 144.393 1.00 40.30  ? 919 THR A C     1 
ATOM   6652 O O     . THR A 1 919 ? 154.022 101.332 145.436 1.00 44.61  ? 919 THR A O     1 
ATOM   6653 C CB    . THR A 1 919 ? 155.927 99.029  143.837 1.00 47.77  ? 919 THR A CB    1 
ATOM   6654 O OG1   . THR A 1 919 ? 154.939 98.285  144.562 1.00 50.47  ? 919 THR A OG1   1 
ATOM   6655 C CG2   . THR A 1 919 ? 157.268 98.323  143.957 1.00 53.11  ? 919 THR A CG2   1 
ATOM   6656 N N     . LEU A 1 920 ? 154.171 101.428 143.185 1.00 35.39  ? 920 LEU A N     1 
ATOM   6657 C CA    . LEU A 1 920 ? 152.869 102.073 143.044 1.00 35.49  ? 920 LEU A CA    1 
ATOM   6658 C C     . LEU A 1 920 ? 151.733 101.156 143.483 1.00 37.36  ? 920 LEU A C     1 
ATOM   6659 O O     . LEU A 1 920 ? 150.727 101.630 144.027 1.00 41.79  ? 920 LEU A O     1 
ATOM   6660 C CB    . LEU A 1 920 ? 152.668 102.531 141.599 1.00 32.77  ? 920 LEU A CB    1 
ATOM   6661 C CG    . LEU A 1 920 ? 151.651 103.646 141.351 1.00 36.64  ? 920 LEU A CG    1 
ATOM   6662 C CD1   . LEU A 1 920 ? 150.271 103.093 141.065 1.00 36.97  ? 920 LEU A CD1   1 
ATOM   6663 C CD2   . LEU A 1 920 ? 151.609 104.592 142.536 1.00 38.30  ? 920 LEU A CD2   1 
ATOM   6664 N N     . GLU A 1 921 ? 151.872 99.846  143.265 1.00 35.11  ? 921 GLU A N     1 
ATOM   6665 C CA    . GLU A 1 921 ? 150.864 98.911  143.756 1.00 35.67  ? 921 GLU A CA    1 
ATOM   6666 C C     . GLU A 1 921 ? 150.814 98.901  145.278 1.00 40.94  ? 921 GLU A C     1 
ATOM   6667 O O     . GLU A 1 921 ? 149.731 98.818  145.868 1.00 46.73  ? 921 GLU A O     1 
ATOM   6668 C CB    . GLU A 1 921 ? 151.132 97.506  143.218 1.00 38.87  ? 921 GLU A CB    1 
ATOM   6669 C CG    . GLU A 1 921 ? 150.118 96.475  143.694 1.00 45.07  ? 921 GLU A CG    1 
ATOM   6670 C CD    . GLU A 1 921 ? 149.839 95.399  142.662 1.00 57.98  ? 921 GLU A CD    1 
ATOM   6671 O OE1   . GLU A 1 921 ? 150.794 94.933  142.006 1.00 65.23  ? 921 GLU A OE1   1 
ATOM   6672 O OE2   . GLU A 1 921 ? 148.657 95.026  142.502 1.00 63.42  ? 921 GLU A OE2   1 
ATOM   6673 N N     . SER A 1 922 ? 151.977 98.973  145.931 1.00 39.13  ? 922 SER A N     1 
ATOM   6674 C CA    . SER A 1 922 ? 152.000 99.044  147.388 1.00 39.21  ? 922 SER A CA    1 
ATOM   6675 C C     . SER A 1 922 ? 151.277 100.288 147.883 1.00 42.92  ? 922 SER A C     1 
ATOM   6676 O O     . SER A 1 922 ? 150.491 100.225 148.838 1.00 45.14  ? 922 SER A O     1 
ATOM   6677 C CB    . SER A 1 922 ? 153.443 99.029  147.890 1.00 42.37  ? 922 SER A CB    1 
ATOM   6678 O OG    . SER A 1 922 ? 154.102 97.832  147.519 1.00 44.00  ? 922 SER A OG    1 
ATOM   6679 N N     . LEU A 1 923 ? 151.522 101.428 147.235 1.00 40.62  ? 923 LEU A N     1 
ATOM   6680 C CA    . LEU A 1 923 ? 150.844 102.662 147.612 1.00 42.57  ? 923 LEU A CA    1 
ATOM   6681 C C     . LEU A 1 923 ? 149.339 102.535 147.428 1.00 40.74  ? 923 LEU A C     1 
ATOM   6682 O O     . LEU A 1 923 ? 148.561 102.961 148.291 1.00 44.58  ? 923 LEU A O     1 
ATOM   6683 C CB    . LEU A 1 923 ? 151.397 103.822 146.783 1.00 40.10  ? 923 LEU A CB    1 
ATOM   6684 C CG    . LEU A 1 923 ? 151.228 105.279 147.226 1.00 41.71  ? 923 LEU A CG    1 
ATOM   6685 C CD1   . LEU A 1 923 ? 152.043 106.167 146.315 1.00 44.00  ? 923 LEU A CD1   1 
ATOM   6686 C CD2   . LEU A 1 923 ? 149.779 105.731 147.215 1.00 37.31  ? 923 LEU A CD2   1 
ATOM   6687 N N     . LEU A 1 924 ? 148.910 101.965 146.301 1.00 35.82  ? 924 LEU A N     1 
ATOM   6688 C CA    . LEU A 1 924 ? 147.482 101.844 146.039 1.00 34.20  ? 924 LEU A CA    1 
ATOM   6689 C C     . LEU A 1 924 ? 146.811 100.916 147.040 1.00 37.94  ? 924 LEU A C     1 
ATOM   6690 O O     . LEU A 1 924 ? 145.703 101.200 147.506 1.00 46.01  ? 924 LEU A O     1 
ATOM   6691 C CB    . LEU A 1 924 ? 147.250 101.361 144.612 1.00 37.53  ? 924 LEU A CB    1 
ATOM   6692 C CG    . LEU A 1 924 ? 146.897 102.450 143.601 1.00 37.12  ? 924 LEU A CG    1 
ATOM   6693 C CD1   . LEU A 1 924 ? 147.839 103.635 143.704 1.00 36.60  ? 924 LEU A CD1   1 
ATOM   6694 C CD2   . LEU A 1 924 ? 146.926 101.862 142.207 1.00 37.80  ? 924 LEU A CD2   1 
ATOM   6695 N N     . ALA A 1 925 ? 147.466 99.808  147.393 1.00 38.24  ? 925 ALA A N     1 
ATOM   6696 C CA    . ALA A 1 925 ? 146.908 98.917  148.406 1.00 41.52  ? 925 ALA A CA    1 
ATOM   6697 C C     . ALA A 1 925 ? 146.826 99.606  149.764 1.00 44.35  ? 925 ALA A C     1 
ATOM   6698 O O     . ALA A 1 925 ? 145.824 99.469  150.481 1.00 39.57  ? 925 ALA A O     1 
ATOM   6699 C CB    . ALA A 1 925 ? 147.742 97.640  148.497 1.00 35.54  ? 925 ALA A CB    1 
ATOM   6700 N N     . HIS A 1 926 ? 147.867 100.358 150.130 1.00 43.77  ? 926 HIS A N     1 
ATOM   6701 C CA    . HIS A 1 926 ? 147.854 101.073 151.401 1.00 42.44  ? 926 HIS A CA    1 
ATOM   6702 C C     . HIS A 1 926 ? 146.713 102.083 151.449 1.00 40.15  ? 926 HIS A C     1 
ATOM   6703 O O     . HIS A 1 926 ? 145.990 102.174 152.446 1.00 44.11  ? 926 HIS A O     1 
ATOM   6704 C CB    . HIS A 1 926 ? 149.205 101.757 151.619 1.00 41.14  ? 926 HIS A CB    1 
ATOM   6705 C CG    . HIS A 1 926 ? 149.321 102.475 152.928 1.00 45.79  ? 926 HIS A CG    1 
ATOM   6706 N ND1   . HIS A 1 926 ? 150.385 103.296 153.231 1.00 48.59  ? 926 HIS A ND1   1 
ATOM   6707 C CD2   . HIS A 1 926 ? 148.512 102.493 154.014 1.00 47.78  ? 926 HIS A CD2   1 
ATOM   6708 C CE1   . HIS A 1 926 ? 150.224 103.793 154.444 1.00 46.03  ? 926 HIS A CE1   1 
ATOM   6709 N NE2   . HIS A 1 926 ? 149.094 103.322 154.941 1.00 47.21  ? 926 HIS A NE2   1 
ATOM   6710 N N     . ILE A 1 927 ? 146.524 102.840 150.368 1.00 36.20  ? 927 ILE A N     1 
ATOM   6711 C CA    . ILE A 1 927 ? 145.457 103.835 150.351 1.00 35.45  ? 927 ILE A CA    1 
ATOM   6712 C C     . ILE A 1 927 ? 144.090 103.161 150.339 1.00 39.87  ? 927 ILE A C     1 
ATOM   6713 O O     . ILE A 1 927 ? 143.143 103.640 150.975 1.00 42.45  ? 927 ILE A O     1 
ATOM   6714 C CB    . ILE A 1 927 ? 145.638 104.795 149.163 1.00 32.39  ? 927 ILE A CB    1 
ATOM   6715 C CG1   . ILE A 1 927 ? 146.877 105.654 149.383 1.00 34.08  ? 927 ILE A CG1   1 
ATOM   6716 C CG2   . ILE A 1 927 ? 144.428 105.693 149.008 1.00 32.79  ? 927 ILE A CG2   1 
ATOM   6717 C CD1   . ILE A 1 927 ? 146.878 106.361 150.717 1.00 36.71  ? 927 ILE A CD1   1 
ATOM   6718 N N     . GLN A 1 928 ? 143.964 102.036 149.632 1.00 40.29  ? 928 GLN A N     1 
ATOM   6719 C CA    . GLN A 1 928 ? 142.689 101.329 149.595 1.00 43.34  ? 928 GLN A CA    1 
ATOM   6720 C C     . GLN A 1 928 ? 142.306 100.807 150.972 1.00 45.46  ? 928 GLN A C     1 
ATOM   6721 O O     . GLN A 1 928 ? 141.137 100.881 151.366 1.00 44.52  ? 928 GLN A O     1 
ATOM   6722 C CB    . GLN A 1 928 ? 142.754 100.184 148.586 1.00 45.19  ? 928 GLN A CB    1 
ATOM   6723 C CG    . GLN A 1 928 ? 141.481 99.364  148.501 1.00 46.46  ? 928 GLN A CG    1 
ATOM   6724 C CD    . GLN A 1 928 ? 141.571 98.260  147.470 1.00 59.06  ? 928 GLN A CD    1 
ATOM   6725 O OE1   . GLN A 1 928 ? 142.486 98.238  146.648 1.00 61.65  ? 928 GLN A OE1   1 
ATOM   6726 N NE2   . GLN A 1 928 ? 140.620 97.335  147.508 1.00 63.70  ? 928 GLN A NE2   1 
ATOM   6727 N N     . GLU A 1 929 ? 143.272 100.268 151.719 1.00 49.45  ? 929 GLU A N     1 
ATOM   6728 C CA    . GLU A 1 929 ? 142.955 99.784  153.058 1.00 51.66  ? 929 GLU A CA    1 
ATOM   6729 C C     . GLU A 1 929 ? 142.784 100.926 154.055 1.00 48.78  ? 929 GLU A C     1 
ATOM   6730 O O     . GLU A 1 929 ? 142.044 100.779 155.034 1.00 47.85  ? 929 GLU A O     1 
ATOM   6731 C CB    . GLU A 1 929 ? 144.027 98.806  153.545 1.00 55.67  ? 929 GLU A CB    1 
ATOM   6732 C CG    . GLU A 1 929 ? 145.396 99.415  153.772 1.00 56.56  ? 929 GLU A CG    1 
ATOM   6733 C CD    . GLU A 1 929 ? 146.394 98.413  154.315 1.00 62.93  ? 929 GLU A CD    1 
ATOM   6734 O OE1   . GLU A 1 929 ? 145.999 97.256  154.569 1.00 65.48  ? 929 GLU A OE1   1 
ATOM   6735 O OE2   . GLU A 1 929 ? 147.574 98.782  154.489 1.00 63.22  ? 929 GLU A OE2   1 
ATOM   6736 N N     . LEU A 1 930 ? 143.447 102.063 153.830 1.00 46.06  ? 930 LEU A N     1 
ATOM   6737 C CA    . LEU A 1 930 ? 143.288 103.205 154.726 1.00 40.56  ? 930 LEU A CA    1 
ATOM   6738 C C     . LEU A 1 930 ? 141.913 103.841 154.565 1.00 38.99  ? 930 LEU A C     1 
ATOM   6739 O O     . LEU A 1 930 ? 141.230 104.128 155.554 1.00 40.68  ? 930 LEU A O     1 
ATOM   6740 C CB    . LEU A 1 930 ? 144.396 104.227 154.458 1.00 40.41  ? 930 LEU A CB    1 
ATOM   6741 C CG    . LEU A 1 930 ? 144.753 105.286 155.505 1.00 46.72  ? 930 LEU A CG    1 
ATOM   6742 C CD1   . LEU A 1 930 ? 146.134 105.846 155.208 1.00 43.76  ? 930 LEU A CD1   1 
ATOM   6743 C CD2   . LEU A 1 930 ? 143.734 106.414 155.555 1.00 47.71  ? 930 LEU A CD2   1 
ATOM   6744 N N     . GLN A 1 931 ? 141.490 104.068 153.322 1.00 38.85  ? 931 GLN A N     1 
ATOM   6745 C CA    . GLN A 1 931 ? 140.246 104.777 153.053 1.00 39.20  ? 931 GLN A CA    1 
ATOM   6746 C C     . GLN A 1 931 ? 139.034 103.860 152.974 1.00 36.75  ? 931 GLN A C     1 
ATOM   6747 O O     . GLN A 1 931 ? 137.951 104.242 153.431 1.00 35.29  ? 931 GLN A O     1 
ATOM   6748 C CB    . GLN A 1 931 ? 140.362 105.560 151.742 1.00 40.69  ? 931 GLN A CB    1 
ATOM   6749 C CG    . GLN A 1 931 ? 141.272 106.772 151.807 1.00 32.39  ? 931 GLN A CG    1 
ATOM   6750 C CD    . GLN A 1 931 ? 140.557 108.006 152.311 1.00 34.57  ? 931 GLN A CD    1 
ATOM   6751 O OE1   . GLN A 1 931 ? 139.942 107.991 153.376 1.00 37.96  ? 931 GLN A OE1   1 
ATOM   6752 N NE2   . GLN A 1 931 ? 140.627 109.084 151.542 1.00 34.43  ? 931 GLN A NE2   1 
ATOM   6753 N N     . GLY A 1 932 ? 139.190 102.665 152.419 1.00 39.24  ? 932 GLY A N     1 
ATOM   6754 C CA    . GLY A 1 932 ? 138.066 101.802 152.126 1.00 40.37  ? 932 GLY A CA    1 
ATOM   6755 C C     . GLY A 1 932 ? 137.553 101.878 150.705 1.00 45.90  ? 932 GLY A C     1 
ATOM   6756 O O     . GLY A 1 932 ? 136.488 101.319 150.419 1.00 49.05  ? 932 GLY A O     1 
ATOM   6757 N N     . LEU A 1 933 ? 138.274 102.550 149.806 1.00 41.97  ? 933 LEU A N     1 
ATOM   6758 C CA    . LEU A 1 933 ? 137.878 102.707 148.414 1.00 34.46  ? 933 LEU A CA    1 
ATOM   6759 C C     . LEU A 1 933 ? 139.070 102.401 147.521 1.00 43.09  ? 933 LEU A C     1 
ATOM   6760 O O     . LEU A 1 933 ? 140.203 102.764 147.849 1.00 50.71  ? 933 LEU A O     1 
ATOM   6761 C CB    . LEU A 1 933 ? 137.372 104.126 148.139 1.00 32.59  ? 933 LEU A CB    1 
ATOM   6762 C CG    . LEU A 1 933 ? 136.360 104.718 149.121 1.00 33.03  ? 933 LEU A CG    1 
ATOM   6763 C CD1   . LEU A 1 933 ? 136.160 106.186 148.842 1.00 31.86  ? 933 LEU A CD1   1 
ATOM   6764 C CD2   . LEU A 1 933 ? 135.034 103.981 149.050 1.00 38.63  ? 933 LEU A CD2   1 
ATOM   6765 N N     . ARG A 1 934 ? 138.820 101.735 146.395 1.00 41.70  ? 934 ARG A N     1 
ATOM   6766 C CA    . ARG A 1 934 ? 139.907 101.369 145.495 1.00 39.04  ? 934 ARG A CA    1 
ATOM   6767 C C     . ARG A 1 934 ? 140.283 102.554 144.613 1.00 33.29  ? 934 ARG A C     1 
ATOM   6768 O O     . ARG A 1 934 ? 139.413 103.246 144.077 1.00 35.72  ? 934 ARG A O     1 
ATOM   6769 C CB    . ARG A 1 934 ? 139.530 100.152 144.647 1.00 41.26  ? 934 ARG A CB    1 
ATOM   6770 C CG    . ARG A 1 934 ? 138.382 100.346 143.678 1.00 47.43  ? 934 ARG A CG    1 
ATOM   6771 C CD    . ARG A 1 934 ? 138.076 99.043  142.961 1.00 58.49  ? 934 ARG A CD    1 
ATOM   6772 N NE    . ARG A 1 934 ? 137.057 99.208  141.932 1.00 67.09  ? 934 ARG A NE    1 
ATOM   6773 C CZ    . ARG A 1 934 ? 137.313 99.292  140.633 1.00 69.92  ? 934 ARG A CZ    1 
ATOM   6774 N NH1   . ARG A 1 934 ? 138.548 99.215  140.165 1.00 70.33  ? 934 ARG A NH1   1 
ATOM   6775 N NH2   . ARG A 1 934 ? 136.303 99.453  139.783 1.00 74.75  ? 934 ARG A NH2   1 
ATOM   6776 N N     . VAL A 1 935 ? 141.584 102.802 144.485 1.00 33.36  ? 935 VAL A N     1 
ATOM   6777 C CA    . VAL A 1 935 ? 142.065 103.955 143.729 1.00 32.17  ? 935 VAL A CA    1 
ATOM   6778 C C     . VAL A 1 935 ? 141.918 103.654 142.241 1.00 34.85  ? 935 VAL A C     1 
ATOM   6779 O O     . VAL A 1 935 ? 142.641 102.818 141.691 1.00 36.12  ? 935 VAL A O     1 
ATOM   6780 C CB    . VAL A 1 935 ? 143.515 104.299 144.083 1.00 31.49  ? 935 VAL A CB    1 
ATOM   6781 C CG1   . VAL A 1 935 ? 144.071 105.304 143.088 1.00 27.35  ? 935 VAL A CG1   1 
ATOM   6782 C CG2   . VAL A 1 935 ? 143.596 104.852 145.494 1.00 31.20  ? 935 VAL A CG2   1 
ATOM   6783 N N     . THR A 1 936 ? 140.985 104.339 141.585 1.00 30.80  ? 936 THR A N     1 
ATOM   6784 C CA    . THR A 1 936 ? 140.799 104.187 140.151 1.00 21.27  ? 936 THR A CA    1 
ATOM   6785 C C     . THR A 1 936 ? 141.603 105.186 139.336 1.00 22.70  ? 936 THR A C     1 
ATOM   6786 O O     . THR A 1 936 ? 141.720 105.012 138.118 1.00 31.75  ? 936 THR A O     1 
ATOM   6787 C CB    . THR A 1 936 ? 139.320 104.319 139.793 1.00 21.35  ? 936 THR A CB    1 
ATOM   6788 O OG1   . THR A 1 936 ? 138.836 105.593 140.234 1.00 30.10  ? 936 THR A OG1   1 
ATOM   6789 C CG2   . THR A 1 936 ? 138.517 103.217 140.461 1.00 28.35  ? 936 THR A CG2   1 
ATOM   6790 N N     . MET A 1 937 ? 142.158 106.220 139.966 1.00 20.19  ? 937 MET A N     1 
ATOM   6791 C CA    . MET A 1 937 ? 142.938 107.201 139.224 1.00 22.77  ? 937 MET A CA    1 
ATOM   6792 C C     . MET A 1 937 ? 143.925 107.883 140.161 1.00 24.80  ? 937 MET A C     1 
ATOM   6793 O O     . MET A 1 937 ? 143.596 108.192 141.307 1.00 30.65  ? 937 MET A O     1 
ATOM   6794 C CB    . MET A 1 937 ? 142.019 108.230 138.559 1.00 25.74  ? 937 MET A CB    1 
ATOM   6795 C CG    . MET A 1 937 ? 142.682 109.053 137.482 1.00 29.31  ? 937 MET A CG    1 
ATOM   6796 S SD    . MET A 1 937 ? 141.500 109.772 136.330 1.00 56.72  ? 937 MET A SD    1 
ATOM   6797 C CE    . MET A 1 937 ? 140.758 108.299 135.637 1.00 41.90  ? 937 MET A CE    1 
ATOM   6798 N N     . LEU A 1 938 ? 145.126 108.141 139.648 1.00 23.74  ? 938 LEU A N     1 
ATOM   6799 C CA    . LEU A 1 938 ? 146.183 108.792 140.416 1.00 21.00  ? 938 LEU A CA    1 
ATOM   6800 C C     . LEU A 1 938 ? 147.020 109.629 139.464 1.00 23.55  ? 938 LEU A C     1 
ATOM   6801 O O     . LEU A 1 938 ? 147.549 109.098 138.483 1.00 30.36  ? 938 LEU A O     1 
ATOM   6802 C CB    . LEU A 1 938 ? 147.052 107.759 141.132 1.00 23.96  ? 938 LEU A CB    1 
ATOM   6803 C CG    . LEU A 1 938 ? 148.227 108.274 141.958 1.00 27.60  ? 938 LEU A CG    1 
ATOM   6804 C CD1   . LEU A 1 938 ? 147.731 109.152 143.085 1.00 27.70  ? 938 LEU A CD1   1 
ATOM   6805 C CD2   . LEU A 1 938 ? 149.021 107.111 142.509 1.00 30.72  ? 938 LEU A CD2   1 
ATOM   6806 N N     . LEU A 1 939 ? 147.133 110.923 139.761 1.00 21.20  ? 939 LEU A N     1 
ATOM   6807 C CA    . LEU A 1 939 ? 147.863 111.880 138.943 1.00 21.52  ? 939 LEU A CA    1 
ATOM   6808 C C     . LEU A 1 939 ? 148.839 112.659 139.811 1.00 25.32  ? 939 LEU A C     1 
ATOM   6809 O O     . LEU A 1 939 ? 148.699 112.706 141.035 1.00 30.71  ? 939 LEU A O     1 
ATOM   6810 C CB    . LEU A 1 939 ? 146.923 112.874 138.241 1.00 22.28  ? 939 LEU A CB    1 
ATOM   6811 C CG    . LEU A 1 939 ? 145.758 112.405 137.367 1.00 28.69  ? 939 LEU A CG    1 
ATOM   6812 C CD1   . LEU A 1 939 ? 144.500 112.155 138.188 1.00 29.07  ? 939 LEU A CD1   1 
ATOM   6813 C CD2   . LEU A 1 939 ? 145.489 113.429 136.278 1.00 27.79  ? 939 LEU A CD2   1 
ATOM   6814 N N     . HIS A 1 940 ? 149.851 113.247 139.175 1.00 25.52  ? 940 HIS A N     1 
ATOM   6815 C CA    . HIS A 1 940 ? 150.704 114.251 139.814 1.00 26.37  ? 940 HIS A CA    1 
ATOM   6816 C C     . HIS A 1 940 ? 150.481 115.580 139.099 1.00 34.30  ? 940 HIS A C     1 
ATOM   6817 O O     . HIS A 1 940 ? 151.220 115.945 138.184 1.00 34.69  ? 940 HIS A O     1 
ATOM   6818 C CB    . HIS A 1 940 ? 152.170 113.841 139.777 1.00 29.46  ? 940 HIS A CB    1 
ATOM   6819 C CG    . HIS A 1 940 ? 153.077 114.765 140.527 1.00 33.47  ? 940 HIS A CG    1 
ATOM   6820 N ND1   . HIS A 1 940 ? 154.446 114.628 140.523 1.00 37.15  ? 940 HIS A ND1   1 
ATOM   6821 C CD2   . HIS A 1 940 ? 152.810 115.837 141.310 1.00 33.50  ? 940 HIS A CD2   1 
ATOM   6822 C CE1   . HIS A 1 940 ? 154.985 115.575 141.269 1.00 41.33  ? 940 HIS A CE1   1 
ATOM   6823 N NE2   . HIS A 1 940 ? 154.014 116.323 141.758 1.00 36.41  ? 940 HIS A NE2   1 
ATOM   6824 N N     . GLY A 1 941 ? 149.461 116.314 139.531 1.00 39.35  ? 941 GLY A N     1 
ATOM   6825 C CA    . GLY A 1 941 ? 149.176 117.611 138.953 1.00 36.33  ? 941 GLY A CA    1 
ATOM   6826 C C     . GLY A 1 941 ? 148.478 117.514 137.614 1.00 35.38  ? 941 GLY A C     1 
ATOM   6827 O O     . GLY A 1 941 ? 147.301 117.865 137.495 1.00 36.33  ? 941 GLY A O     1 
ATOM   6828 N N     . SER A 1 942 ? 149.201 117.050 136.592 1.00 34.73  ? 942 SER A N     1 
ATOM   6829 C CA    . SER A 1 942 ? 148.616 116.826 135.278 1.00 31.80  ? 942 SER A CA    1 
ATOM   6830 C C     . SER A 1 942 ? 149.147 115.582 134.577 1.00 30.96  ? 942 SER A C     1 
ATOM   6831 O O     . SER A 1 942 ? 148.719 115.307 133.453 1.00 35.99  ? 942 SER A O     1 
ATOM   6832 C CB    . SER A 1 942 ? 148.843 118.050 134.374 1.00 36.09  ? 942 SER A CB    1 
ATOM   6833 O OG    . SER A 1 942 ? 148.167 119.195 134.866 1.00 45.31  ? 942 SER A OG    1 
ATOM   6834 N N     . ALA A 1 943 ? 150.056 114.829 135.190 1.00 28.28  ? 943 ALA A N     1 
ATOM   6835 C CA    . ALA A 1 943 ? 150.576 113.596 134.614 1.00 27.75  ? 943 ALA A CA    1 
ATOM   6836 C C     . ALA A 1 943 ? 149.880 112.407 135.261 1.00 32.17  ? 943 ALA A C     1 
ATOM   6837 O O     . ALA A 1 943 ? 149.918 112.251 136.485 1.00 38.53  ? 943 ALA A O     1 
ATOM   6838 C CB    . ALA A 1 943 ? 152.089 113.493 134.810 1.00 27.82  ? 943 ALA A CB    1 
ATOM   6839 N N     . LEU A 1 944 ? 149.262 111.566 134.438 1.00 27.85  ? 944 LEU A N     1 
ATOM   6840 C CA    . LEU A 1 944 ? 148.467 110.451 134.937 1.00 25.33  ? 944 LEU A CA    1 
ATOM   6841 C C     . LEU A 1 944 ? 149.397 109.296 135.291 1.00 33.72  ? 944 LEU A C     1 
ATOM   6842 O O     . LEU A 1 944 ? 149.933 108.625 134.402 1.00 41.54  ? 944 LEU A O     1 
ATOM   6843 C CB    . LEU A 1 944 ? 147.435 110.039 133.894 1.00 30.17  ? 944 LEU A CB    1 
ATOM   6844 C CG    . LEU A 1 944 ? 146.439 108.952 134.288 1.00 30.70  ? 944 LEU A CG    1 
ATOM   6845 C CD1   . LEU A 1 944 ? 145.736 109.304 135.584 1.00 29.15  ? 944 LEU A CD1   1 
ATOM   6846 C CD2   . LEU A 1 944 ? 145.425 108.752 133.184 1.00 33.95  ? 944 LEU A CD2   1 
ATOM   6847 N N     . LEU A 1 945 ? 149.599 109.070 136.592 1.00 30.87  ? 945 LEU A N     1 
ATOM   6848 C CA    . LEU A 1 945 ? 150.421 107.952 137.043 1.00 28.13  ? 945 LEU A CA    1 
ATOM   6849 C C     . LEU A 1 945 ? 149.705 106.622 136.872 1.00 30.49  ? 945 LEU A C     1 
ATOM   6850 O O     . LEU A 1 945 ? 150.329 105.628 136.485 1.00 38.92  ? 945 LEU A O     1 
ATOM   6851 C CB    . LEU A 1 945 ? 150.813 108.128 138.508 1.00 28.05  ? 945 LEU A CB    1 
ATOM   6852 C CG    . LEU A 1 945 ? 151.970 109.053 138.868 1.00 31.63  ? 945 LEU A CG    1 
ATOM   6853 C CD1   . LEU A 1 945 ? 151.531 110.497 138.853 1.00 28.34  ? 945 LEU A CD1   1 
ATOM   6854 C CD2   . LEU A 1 945 ? 152.512 108.673 140.232 1.00 48.09  ? 945 LEU A CD2   1 
ATOM   6855 N N     . TYR A 1 946 ? 148.410 106.578 137.177 1.00 26.67  ? 946 TYR A N     1 
ATOM   6856 C CA    . TYR A 1 946 ? 147.679 105.321 137.127 1.00 27.49  ? 946 TYR A CA    1 
ATOM   6857 C C     . TYR A 1 946 ? 146.204 105.575 136.856 1.00 31.39  ? 946 TYR A C     1 
ATOM   6858 O O     . TYR A 1 946 ? 145.643 106.571 137.314 1.00 30.74  ? 946 TYR A O     1 
ATOM   6859 C CB    . TYR A 1 946 ? 147.851 104.537 138.433 1.00 24.62  ? 946 TYR A CB    1 
ATOM   6860 C CG    . TYR A 1 946 ? 146.957 103.330 138.547 1.00 23.73  ? 946 TYR A CG    1 
ATOM   6861 C CD1   . TYR A 1 946 ? 147.289 102.135 137.930 1.00 30.09  ? 946 TYR A CD1   1 
ATOM   6862 C CD2   . TYR A 1 946 ? 145.779 103.384 139.273 1.00 25.23  ? 946 TYR A CD2   1 
ATOM   6863 C CE1   . TYR A 1 946 ? 146.471 101.030 138.030 1.00 32.27  ? 946 TYR A CE1   1 
ATOM   6864 C CE2   . TYR A 1 946 ? 144.954 102.282 139.379 1.00 27.12  ? 946 TYR A CE2   1 
ATOM   6865 C CZ    . TYR A 1 946 ? 145.307 101.108 138.758 1.00 30.57  ? 946 TYR A CZ    1 
ATOM   6866 O OH    . TYR A 1 946 ? 144.490 100.005 138.859 1.00 38.25  ? 946 TYR A OH    1 
ATOM   6867 N N     . SER A 1 947 ? 145.585 104.669 136.104 1.00 31.92  ? 947 SER A N     1 
ATOM   6868 C CA    . SER A 1 947 ? 144.141 104.666 135.933 1.00 26.24  ? 947 SER A CA    1 
ATOM   6869 C C     . SER A 1 947 ? 143.667 103.239 135.713 1.00 28.58  ? 947 SER A C     1 
ATOM   6870 O O     . SER A 1 947 ? 144.317 102.465 135.004 1.00 36.10  ? 947 SER A O     1 
ATOM   6871 C CB    . SER A 1 947 ? 143.711 105.553 134.765 1.00 33.25  ? 947 SER A CB    1 
ATOM   6872 O OG    . SER A 1 947 ? 142.302 105.548 134.634 1.00 44.36  ? 947 SER A OG    1 
ATOM   6873 N N     . ALA A 1 948 ? 142.536 102.895 136.328 1.00 25.34  ? 948 ALA A N     1 
ATOM   6874 C CA    . ALA A 1 948 ? 141.975 101.558 136.186 1.00 26.41  ? 948 ALA A CA    1 
ATOM   6875 C C     . ALA A 1 948 ? 141.337 101.331 134.825 1.00 38.17  ? 948 ALA A C     1 
ATOM   6876 O O     . ALA A 1 948 ? 141.085 100.176 134.465 1.00 47.55  ? 948 ALA A O     1 
ATOM   6877 C CB    . ALA A 1 948 ? 140.949 101.301 137.289 1.00 23.48  ? 948 ALA A CB    1 
ATOM   6878 N N     . GLY A 1 949 ? 141.090 102.397 134.058 1.00 37.21  ? 949 GLY A N     1 
ATOM   6879 C CA    . GLY A 1 949 ? 140.595 102.249 132.702 1.00 36.89  ? 949 GLY A CA    1 
ATOM   6880 C C     . GLY A 1 949 ? 141.633 101.761 131.721 1.00 32.02  ? 949 GLY A C     1 
ATOM   6881 O O     . GLY A 1 949 ? 141.292 101.438 130.579 1.00 40.98  ? 949 GLY A O     1 
ATOM   6882 N N     . TRP A 1 950 ? 142.889 101.701 132.141 1.00 27.15  ? 950 TRP A N     1 
ATOM   6883 C CA    . TRP A 1 950 ? 143.968 101.291 131.263 1.00 35.60  ? 950 TRP A CA    1 
ATOM   6884 C C     . TRP A 1 950 ? 143.904 99.796  130.963 1.00 40.84  ? 950 TRP A C     1 
ATOM   6885 O O     . TRP A 1 950 ? 143.261 99.016  131.669 1.00 39.55  ? 950 TRP A O     1 
ATOM   6886 C CB    . TRP A 1 950 ? 145.314 101.631 131.895 1.00 38.61  ? 950 TRP A CB    1 
ATOM   6887 C CG    . TRP A 1 950 ? 145.687 103.064 131.783 1.00 37.02  ? 950 TRP A CG    1 
ATOM   6888 C CD1   . TRP A 1 950 ? 145.112 104.000 130.976 1.00 38.06  ? 950 TRP A CD1   1 
ATOM   6889 C CD2   . TRP A 1 950 ? 146.726 103.733 132.501 1.00 34.85  ? 950 TRP A CD2   1 
ATOM   6890 N NE1   . TRP A 1 950 ? 145.731 105.213 131.146 1.00 36.09  ? 950 TRP A NE1   1 
ATOM   6891 C CE2   . TRP A 1 950 ? 146.727 105.074 132.076 1.00 37.29  ? 950 TRP A CE2   1 
ATOM   6892 C CE3   . TRP A 1 950 ? 147.652 103.330 133.466 1.00 39.11  ? 950 TRP A CE3   1 
ATOM   6893 C CZ2   . TRP A 1 950 ? 147.624 106.011 132.575 1.00 38.50  ? 950 TRP A CZ2   1 
ATOM   6894 C CZ3   . TRP A 1 950 ? 148.540 104.260 133.957 1.00 39.99  ? 950 TRP A CZ3   1 
ATOM   6895 C CH2   . TRP A 1 950 ? 148.521 105.585 133.514 1.00 38.50  ? 950 TRP A CH2   1 
ATOM   6896 N N     . SER A 1 951 ? 144.593 99.403  129.892 1.00 43.58  ? 951 SER A N     1 
ATOM   6897 C CA    . SER A 1 951 ? 144.795 97.991  129.600 1.00 41.60  ? 951 SER A CA    1 
ATOM   6898 C C     . SER A 1 951 ? 145.687 97.352  130.660 1.00 43.02  ? 951 SER A C     1 
ATOM   6899 O O     . SER A 1 951 ? 146.400 98.035  131.398 1.00 43.61  ? 951 SER A O     1 
ATOM   6900 C CB    . SER A 1 951 ? 145.410 97.817  128.209 1.00 44.89  ? 951 SER A CB    1 
ATOM   6901 O OG    . SER A 1 951 ? 146.612 98.556  128.074 1.00 51.27  ? 951 SER A OG    1 
ATOM   6902 N N     . GLU A 1 952 ? 145.630 96.020  130.740 1.00 44.00  ? 952 GLU A N     1 
ATOM   6903 C CA    . GLU A 1 952 ? 146.343 95.314  131.800 1.00 43.62  ? 952 GLU A CA    1 
ATOM   6904 C C     . GLU A 1 952 ? 147.847 95.553  131.732 1.00 48.77  ? 952 GLU A C     1 
ATOM   6905 O O     . GLU A 1 952 ? 148.490 95.777  132.764 1.00 54.11  ? 952 GLU A O     1 
ATOM   6906 C CB    . GLU A 1 952 ? 146.037 93.818  131.735 1.00 54.46  ? 952 GLU A CB    1 
ATOM   6907 C CG    . GLU A 1 952 ? 144.587 93.455  132.034 1.00 60.02  ? 952 GLU A CG    1 
ATOM   6908 C CD    . GLU A 1 952 ? 144.259 93.500  133.516 1.00 69.06  ? 952 GLU A CD    1 
ATOM   6909 O OE1   . GLU A 1 952 ? 145.152 93.844  134.318 1.00 71.90  ? 952 GLU A OE1   1 
ATOM   6910 O OE2   . GLU A 1 952 ? 143.108 93.186  133.884 1.00 67.08  ? 952 GLU A OE2   1 
ATOM   6911 N N     . GLU A 1 953 ? 148.432 95.502  130.531 1.00 50.00  ? 953 GLU A N     1 
ATOM   6912 C CA    . GLU A 1 953 ? 149.884 95.614  130.424 1.00 50.72  ? 953 GLU A CA    1 
ATOM   6913 C C     . GLU A 1 953 ? 150.375 96.983  130.890 1.00 51.18  ? 953 GLU A C     1 
ATOM   6914 O O     . GLU A 1 953 ? 151.359 97.075  131.635 1.00 52.04  ? 953 GLU A O     1 
ATOM   6915 C CB    . GLU A 1 953 ? 150.340 95.323  128.990 1.00 53.14  ? 953 GLU A CB    1 
ATOM   6916 C CG    . GLU A 1 953 ? 149.831 96.280  127.919 1.00 54.99  ? 953 GLU A CG    1 
ATOM   6917 C CD    . GLU A 1 953 ? 148.494 95.865  127.338 1.00 61.56  ? 953 GLU A CD    1 
ATOM   6918 O OE1   . GLU A 1 953 ? 147.955 94.820  127.759 1.00 58.32  ? 953 GLU A OE1   1 
ATOM   6919 O OE2   . GLU A 1 953 ? 147.985 96.583  126.452 1.00 63.13  ? 953 GLU A OE2   1 
ATOM   6920 N N     . LYS A 1 954 ? 149.685 98.053  130.488 1.00 50.90  ? 954 LYS A N     1 
ATOM   6921 C CA    . LYS A 1 954 ? 150.072 99.398  130.905 1.00 53.16  ? 954 LYS A CA    1 
ATOM   6922 C C     . LYS A 1 954 ? 149.872 99.589  132.405 1.00 50.73  ? 954 LYS A C     1 
ATOM   6923 O O     . LYS A 1 954 ? 150.721 100.189 133.081 1.00 47.58  ? 954 LYS A O     1 
ATOM   6924 C CB    . LYS A 1 954 ? 149.277 100.432 130.105 1.00 46.57  ? 954 LYS A CB    1 
ATOM   6925 C CG    . LYS A 1 954 ? 149.137 101.797 130.760 1.00 47.48  ? 954 LYS A CG    1 
ATOM   6926 C CD    . LYS A 1 954 ? 150.412 102.630 130.684 1.00 55.55  ? 954 LYS A CD    1 
ATOM   6927 C CE    . LYS A 1 954 ? 150.731 103.066 129.261 1.00 63.18  ? 954 LYS A CE    1 
ATOM   6928 N NZ    . LYS A 1 954 ? 151.933 103.946 129.208 1.00 66.87  ? 954 LYS A NZ    1 
ATOM   6929 N N     . GLN A 1 955 ? 148.764 99.070  132.942 1.00 50.08  ? 955 GLN A N     1 
ATOM   6930 C CA    . GLN A 1 955 ? 148.542 99.116  134.383 1.00 42.33  ? 955 GLN A CA    1 
ATOM   6931 C C     . GLN A 1 955 ? 149.680 98.445  135.135 1.00 46.10  ? 955 GLN A C     1 
ATOM   6932 O O     . GLN A 1 955 ? 150.221 99.013  136.084 1.00 50.44  ? 955 GLN A O     1 
ATOM   6933 C CB    . GLN A 1 955 ? 147.216 98.449  134.746 1.00 36.33  ? 955 GLN A CB    1 
ATOM   6934 C CG    . GLN A 1 955 ? 146.010 99.357  134.719 1.00 33.68  ? 955 GLN A CG    1 
ATOM   6935 C CD    . GLN A 1 955 ? 144.787 98.693  135.317 1.00 37.83  ? 955 GLN A CD    1 
ATOM   6936 O OE1   . GLN A 1 955 ? 144.805 98.261  136.467 1.00 40.40  ? 955 GLN A OE1   1 
ATOM   6937 N NE2   . GLN A 1 955 ? 143.718 98.599  134.536 1.00 40.85  ? 955 GLN A NE2   1 
ATOM   6938 N N     . THR A 1 956 ? 150.044 97.224  134.737 1.00 47.95  ? 956 THR A N     1 
ATOM   6939 C CA    . THR A 1 956 ? 151.088 96.496  135.454 1.00 49.75  ? 956 THR A CA    1 
ATOM   6940 C C     . THR A 1 956 ? 152.440 97.184  135.318 1.00 47.54  ? 956 THR A C     1 
ATOM   6941 O O     . THR A 1 956 ? 153.211 97.248  136.286 1.00 50.35  ? 956 THR A O     1 
ATOM   6942 C CB    . THR A 1 956 ? 151.165 95.053  134.956 1.00 54.41  ? 956 THR A CB    1 
ATOM   6943 O OG1   . THR A 1 956 ? 151.318 95.043  133.532 1.00 60.04  ? 956 THR A OG1   1 
ATOM   6944 C CG2   . THR A 1 956 ? 149.898 94.300  135.328 1.00 48.28  ? 956 THR A CG2   1 
ATOM   6945 N N     . GLN A 1 957 ? 152.741 97.714  134.131 1.00 44.36  ? 957 GLN A N     1 
ATOM   6946 C CA    . GLN A 1 957 ? 153.988 98.445  133.945 1.00 47.12  ? 957 GLN A CA    1 
ATOM   6947 C C     . GLN A 1 957 ? 154.065 99.637  134.888 1.00 49.29  ? 957 GLN A C     1 
ATOM   6948 O O     . GLN A 1 957 ? 155.099 99.878  135.519 1.00 50.88  ? 957 GLN A O     1 
ATOM   6949 C CB    . GLN A 1 957 ? 154.120 98.898  132.493 1.00 48.69  ? 957 GLN A CB    1 
ATOM   6950 C CG    . GLN A 1 957 ? 154.407 97.778  131.513 1.00 50.16  ? 957 GLN A CG    1 
ATOM   6951 C CD    . GLN A 1 957 ? 154.313 98.240  130.078 1.00 51.88  ? 957 GLN A CD    1 
ATOM   6952 O OE1   . GLN A 1 957 ? 153.990 99.395  129.810 1.00 52.85  ? 957 GLN A OE1   1 
ATOM   6953 N NE2   . GLN A 1 957 ? 154.594 97.338  129.145 1.00 53.79  ? 957 GLN A NE2   1 
ATOM   6954 N N     . HIS A 1 958 ? 152.969 100.390 135.010 1.00 50.78  ? 958 HIS A N     1 
ATOM   6955 C CA    . HIS A 1 958 ? 152.991 101.555 135.887 1.00 47.43  ? 958 HIS A CA    1 
ATOM   6956 C C     . HIS A 1 958 ? 152.948 101.168 137.362 1.00 44.36  ? 958 HIS A C     1 
ATOM   6957 O O     . HIS A 1 958 ? 153.514 101.877 138.202 1.00 48.62  ? 958 HIS A O     1 
ATOM   6958 C CB    . HIS A 1 958 ? 151.843 102.494 135.530 1.00 42.08  ? 958 HIS A CB    1 
ATOM   6959 C CG    . HIS A 1 958 ? 152.109 103.319 134.311 1.00 40.16  ? 958 HIS A CG    1 
ATOM   6960 N ND1   . HIS A 1 958 ? 151.566 104.571 134.124 1.00 42.42  ? 958 HIS A ND1   1 
ATOM   6961 C CD2   . HIS A 1 958 ? 152.878 103.077 133.223 1.00 47.71  ? 958 HIS A CD2   1 
ATOM   6962 C CE1   . HIS A 1 958 ? 151.980 105.062 132.969 1.00 51.69  ? 958 HIS A CE1   1 
ATOM   6963 N NE2   . HIS A 1 958 ? 152.779 104.176 132.403 1.00 55.44  ? 958 HIS A NE2   1 
ATOM   6964 N N     . LEU A 1 959 ? 152.286 100.060 137.699 1.00 39.05  ? 959 LEU A N     1 
ATOM   6965 C CA    . LEU A 1 959 ? 152.216 99.617  139.086 1.00 35.78  ? 959 LEU A CA    1 
ATOM   6966 C C     . LEU A 1 959 ? 153.561 99.109  139.582 1.00 37.79  ? 959 LEU A C     1 
ATOM   6967 O O     . LEU A 1 959 ? 153.888 99.280  140.762 1.00 42.72  ? 959 LEU A O     1 
ATOM   6968 C CB    . LEU A 1 959 ? 151.151 98.532  139.238 1.00 36.15  ? 959 LEU A CB    1 
ATOM   6969 C CG    . LEU A 1 959 ? 149.690 98.961  139.088 1.00 37.81  ? 959 LEU A CG    1 
ATOM   6970 C CD1   . LEU A 1 959 ? 148.805 97.738  138.903 1.00 44.56  ? 959 LEU A CD1   1 
ATOM   6971 C CD2   . LEU A 1 959 ? 149.232 99.771  140.282 1.00 32.24  ? 959 LEU A CD2   1 
ATOM   6972 N N     . SER A 1 960 ? 154.352 98.489  138.707 1.00 41.86  ? 960 SER A N     1 
ATOM   6973 C CA    . SER A 1 960 ? 155.660 98.001  139.124 1.00 47.88  ? 960 SER A CA    1 
ATOM   6974 C C     . SER A 1 960 ? 156.646 99.136  139.372 1.00 49.05  ? 960 SER A C     1 
ATOM   6975 O O     . SER A 1 960 ? 157.564 98.985  140.187 1.00 52.10  ? 960 SER A O     1 
ATOM   6976 C CB    . SER A 1 960 ? 156.220 97.040  138.074 1.00 54.72  ? 960 SER A CB    1 
ATOM   6977 O OG    . SER A 1 960 ? 157.490 96.546  138.460 1.00 62.75  ? 960 SER A OG    1 
ATOM   6978 N N     . ARG A 1 961 ? 156.481 100.265 138.690 1.00 47.46  ? 961 ARG A N     1 
ATOM   6979 C CA    . ARG A 1 961 ? 157.400 101.383 138.842 1.00 50.70  ? 961 ARG A CA    1 
ATOM   6980 C C     . ARG A 1 961 ? 157.184 102.097 140.172 1.00 52.15  ? 961 ARG A C     1 
ATOM   6981 O O     . ARG A 1 961 ? 156.082 102.108 140.727 1.00 54.46  ? 961 ARG A O     1 
ATOM   6982 C CB    . ARG A 1 961 ? 157.225 102.371 137.689 1.00 56.84  ? 961 ARG A CB    1 
ATOM   6983 C CG    . ARG A 1 961 ? 157.430 101.759 136.313 1.00 59.93  ? 961 ARG A CG    1 
ATOM   6984 C CD    . ARG A 1 961 ? 158.880 101.813 135.880 1.00 64.50  ? 961 ARG A CD    1 
ATOM   6985 N NE    . ARG A 1 961 ? 159.290 103.178 135.574 1.00 73.43  ? 961 ARG A NE    1 
ATOM   6986 C CZ    . ARG A 1 961 ? 160.432 103.501 134.985 1.00 79.67  ? 961 ARG A CZ    1 
ATOM   6987 N NH1   . ARG A 1 961 ? 161.308 102.579 134.622 1.00 79.34  ? 961 ARG A NH1   1 
ATOM   6988 N NH2   . ARG A 1 961 ? 160.701 104.783 134.752 1.00 81.31  ? 961 ARG A NH2   1 
ATOM   6989 N N     . ARG A 1 962 ? 158.258 102.690 140.686 1.00 51.42  ? 962 ARG A N     1 
ATOM   6990 C CA    . ARG A 1 962 ? 158.170 103.573 141.836 1.00 48.78  ? 962 ARG A CA    1 
ATOM   6991 C C     . ARG A 1 962 ? 157.543 104.904 141.428 1.00 56.92  ? 962 ARG A C     1 
ATOM   6992 O O     . ARG A 1 962 ? 157.537 105.282 140.253 1.00 64.01  ? 962 ARG A O     1 
ATOM   6993 C CB    . ARG A 1 962 ? 159.555 103.809 142.443 1.00 49.42  ? 962 ARG A CB    1 
ATOM   6994 C CG    . ARG A 1 962 ? 160.258 102.552 142.931 1.00 51.78  ? 962 ARG A CG    1 
ATOM   6995 C CD    . ARG A 1 962 ? 161.720 102.826 143.255 1.00 55.21  ? 962 ARG A CD    1 
ATOM   6996 N NE    . ARG A 1 962 ? 162.417 101.630 143.716 1.00 65.22  ? 962 ARG A NE    1 
ATOM   6997 C CZ    . ARG A 1 962 ? 163.698 101.593 144.057 1.00 70.41  ? 962 ARG A CZ    1 
ATOM   6998 N NH1   . ARG A 1 962 ? 164.462 102.672 143.993 1.00 78.17  ? 962 ARG A NH1   1 
ATOM   6999 N NH2   . ARG A 1 962 ? 164.227 100.446 144.471 1.00 62.66  ? 962 ARG A NH2   1 
ATOM   7000 N N     . VAL A 1 963 ? 157.001 105.615 142.418 1.00 50.97  ? 963 VAL A N     1 
ATOM   7001 C CA    . VAL A 1 963 ? 156.379 106.911 142.151 1.00 48.98  ? 963 VAL A CA    1 
ATOM   7002 C C     . VAL A 1 963 ? 157.402 107.895 141.592 1.00 58.91  ? 963 VAL A C     1 
ATOM   7003 O O     . VAL A 1 963 ? 157.138 108.597 140.609 1.00 61.68  ? 963 VAL A O     1 
ATOM   7004 C CB    . VAL A 1 963 ? 155.709 107.456 143.422 1.00 47.80  ? 963 VAL A CB    1 
ATOM   7005 C CG1   . VAL A 1 963 ? 155.298 108.907 143.224 1.00 51.06  ? 963 VAL A CG1   1 
ATOM   7006 C CG2   . VAL A 1 963 ? 154.512 106.606 143.774 1.00 43.37  ? 963 VAL A CG2   1 
ATOM   7007 N N     . THR A 1 964 ? 158.585 107.964 142.209 1.00 53.65  ? 964 THR A N     1 
ATOM   7008 C CA    . THR A 1 964 ? 159.602 108.902 141.744 1.00 53.70  ? 964 THR A CA    1 
ATOM   7009 C C     . THR A 1 964 ? 160.148 108.536 140.369 1.00 65.24  ? 964 THR A C     1 
ATOM   7010 O O     . THR A 1 964 ? 160.768 109.384 139.719 1.00 72.10  ? 964 THR A O     1 
ATOM   7011 C CB    . THR A 1 964 ? 160.751 108.991 142.748 1.00 52.68  ? 964 THR A CB    1 
ATOM   7012 O OG1   . THR A 1 964 ? 161.366 107.706 142.894 1.00 46.95  ? 964 THR A OG1   1 
ATOM   7013 C CG2   . THR A 1 964 ? 160.242 109.467 144.098 1.00 63.61  ? 964 THR A CG2   1 
ATOM   7014 N N     . ASP A 1 965 ? 159.936 107.303 139.911 1.00 61.12  ? 965 ASP A N     1 
ATOM   7015 C CA    . ASP A 1 965 ? 160.295 106.933 138.550 1.00 61.97  ? 965 ASP A CA    1 
ATOM   7016 C C     . ASP A 1 965 ? 159.201 107.264 137.545 1.00 66.08  ? 965 ASP A C     1 
ATOM   7017 O O     . ASP A 1 965 ? 159.429 107.138 136.337 1.00 69.50  ? 965 ASP A O     1 
ATOM   7018 C CB    . ASP A 1 965 ? 160.630 105.440 138.472 1.00 62.33  ? 965 ASP A CB    1 
ATOM   7019 C CG    . ASP A 1 965 ? 161.915 105.095 139.194 1.00 65.61  ? 965 ASP A CG    1 
ATOM   7020 O OD1   . ASP A 1 965 ? 162.821 105.953 139.235 1.00 63.88  ? 965 ASP A OD1   1 
ATOM   7021 O OD2   . ASP A 1 965 ? 162.019 103.969 139.725 1.00 71.17  ? 965 ASP A OD2   1 
ATOM   7022 N N     . LEU A 1 966 ? 158.024 107.676 138.015 1.00 61.23  ? 966 LEU A N     1 
ATOM   7023 C CA    . LEU A 1 966 ? 156.944 108.105 137.140 1.00 62.33  ? 966 LEU A CA    1 
ATOM   7024 C C     . LEU A 1 966 ? 156.810 109.619 137.058 1.00 65.03  ? 966 LEU A C     1 
ATOM   7025 O O     . LEU A 1 966 ? 156.200 110.120 136.107 1.00 68.95  ? 966 LEU A O     1 
ATOM   7026 C CB    . LEU A 1 966 ? 155.614 107.501 137.607 1.00 59.14  ? 966 LEU A CB    1 
ATOM   7027 C CG    . LEU A 1 966 ? 155.522 105.974 137.597 1.00 57.84  ? 966 LEU A CG    1 
ATOM   7028 C CD1   . LEU A 1 966 ? 154.231 105.514 138.256 1.00 47.63  ? 966 LEU A CD1   1 
ATOM   7029 C CD2   . LEU A 1 966 ? 155.619 105.441 136.176 1.00 58.18  ? 966 LEU A CD2   1 
ATOM   7030 N N     . VAL A 1 967 ? 157.374 110.356 138.016 1.00 64.99  ? 967 VAL A N     1 
ATOM   7031 C CA    . VAL A 1 967 ? 157.283 111.810 138.047 1.00 68.64  ? 967 VAL A CA    1 
ATOM   7032 C C     . VAL A 1 967 ? 158.687 112.399 138.130 1.00 72.37  ? 967 VAL A C     1 
ATOM   7033 O O     . VAL A 1 967 ? 159.615 111.777 138.659 1.00 71.75  ? 967 VAL A O     1 
ATOM   7034 C CB    . VAL A 1 967 ? 156.408 112.307 139.222 1.00 59.88  ? 967 VAL A CB    1 
ATOM   7035 C CG1   . VAL A 1 967 ? 155.028 111.671 139.170 1.00 51.92  ? 967 VAL A CG1   1 
ATOM   7036 C CG2   . VAL A 1 967 ? 157.077 112.024 140.556 1.00 59.83  ? 967 VAL A CG2   1 
ATOM   7037 N N     . LYS A 1 968 ? 158.842 113.605 137.585 1.00 78.09  ? 968 LYS A N     1 
ATOM   7038 C CA    . LYS A 1 968 ? 160.122 114.300 137.648 1.00 82.06  ? 968 LYS A CA    1 
ATOM   7039 C C     . LYS A 1 968 ? 160.430 114.697 139.088 1.00 82.23  ? 968 LYS A C     1 
ATOM   7040 O O     . LYS A 1 968 ? 159.571 115.242 139.788 1.00 84.07  ? 968 LYS A O     1 
ATOM   7041 C CB    . LYS A 1 968 ? 160.099 115.535 136.746 1.00 90.05  ? 968 LYS A CB    1 
ATOM   7042 C CG    . LYS A 1 968 ? 161.454 116.214 136.559 1.00 90.78  ? 968 LYS A CG    1 
ATOM   7043 C CD    . LYS A 1 968 ? 162.418 115.342 135.759 1.00 93.28  ? 968 LYS A CD    1 
ATOM   7044 C CE    . LYS A 1 968 ? 163.698 116.095 135.414 1.00 97.80  ? 968 LYS A CE    1 
ATOM   7045 N NZ    . LYS A 1 968 ? 164.379 116.597 136.637 1.00 98.28  ? 968 LYS A NZ    1 
ATOM   7046 N N     . LYS A 1 969 ? 161.652 114.416 139.535 1.00 82.89  ? 969 LYS A N     1 
ATOM   7047 C CA    . LYS A 1 969 ? 162.057 114.710 140.910 1.00 88.27  ? 969 LYS A CA    1 
ATOM   7048 C C     . LYS A 1 969 ? 162.481 116.171 140.997 1.00 83.86  ? 969 LYS A C     1 
ATOM   7049 O O     . LYS A 1 969 ? 163.590 116.534 140.600 1.00 81.02  ? 969 LYS A O     1 
ATOM   7050 C CB    . LYS A 1 969 ? 163.178 113.778 141.356 1.00 92.44  ? 969 LYS A CB    1 
ATOM   7051 C CG    . LYS A 1 969 ? 163.505 113.858 142.844 1.00 94.68  ? 969 LYS A CG    1 
ATOM   7052 C CD    . LYS A 1 969 ? 162.306 113.468 143.697 1.00 94.88  ? 969 LYS A CD    1 
ATOM   7053 C CE    . LYS A 1 969 ? 162.664 113.431 145.175 1.00 91.15  ? 969 LYS A CE    1 
ATOM   7054 N NZ    . LYS A 1 969 ? 163.150 114.750 145.668 1.00 89.75  ? 969 LYS A NZ    1 
ATOM   7055 N N     . VAL A 1 970 ? 161.591 117.013 141.513 1.00 82.39  ? 970 VAL A N     1 
ATOM   7056 C CA    . VAL A 1 970 ? 161.917 118.431 141.699 1.00 82.93  ? 970 VAL A CA    1 
ATOM   7057 C C     . VAL A 1 970 ? 163.014 118.556 142.749 1.00 86.51  ? 970 VAL A C     1 
ATOM   7058 O O     . VAL A 1 970 ? 162.910 117.939 143.828 1.00 86.09  ? 970 VAL A O     1 
ATOM   7059 C CB    . VAL A 1 970 ? 160.665 119.222 142.114 1.00 75.43  ? 970 VAL A CB    1 
ATOM   7060 C CG1   . VAL A 1 970 ? 161.009 120.688 142.360 1.00 80.11  ? 970 VAL A CG1   1 
ATOM   7061 C CG2   . VAL A 1 970 ? 159.587 119.092 141.053 1.00 74.71  ? 970 VAL A CG2   1 
ATOM   7062 N N     . PRO A 1 971 ? 164.086 119.303 142.488 1.00 87.18  ? 971 PRO A N     1 
ATOM   7063 C CA    . PRO A 1 971 ? 165.155 119.434 143.486 1.00 85.74  ? 971 PRO A CA    1 
ATOM   7064 C C     . PRO A 1 971 ? 164.640 120.031 144.788 1.00 81.92  ? 971 PRO A C     1 
ATOM   7065 O O     . PRO A 1 971 ? 163.850 120.977 144.792 1.00 82.41  ? 971 PRO A O     1 
ATOM   7066 C CB    . PRO A 1 971 ? 166.165 120.361 142.801 1.00 88.72  ? 971 PRO A CB    1 
ATOM   7067 C CG    . PRO A 1 971 ? 165.893 120.199 141.337 1.00 88.38  ? 971 PRO A CG    1 
ATOM   7068 C CD    . PRO A 1 971 ? 164.415 119.986 141.226 1.00 88.23  ? 971 PRO A CD    1 
ATOM   7069 N N     . GLY A 1 972 ? 165.096 119.461 145.901 1.00 80.00  ? 972 GLY A N     1 
ATOM   7070 C CA    . GLY A 1 972 ? 164.727 119.949 147.213 1.00 81.05  ? 972 GLY A CA    1 
ATOM   7071 C C     . GLY A 1 972 ? 163.316 119.636 147.656 1.00 79.98  ? 972 GLY A C     1 
ATOM   7072 O O     . GLY A 1 972 ? 162.903 120.112 148.720 1.00 77.39  ? 972 GLY A O     1 
ATOM   7073 N N     . GLN A 1 973 ? 162.563 118.852 146.889 1.00 79.54  ? 973 GLN A N     1 
ATOM   7074 C CA    . GLN A 1 973 ? 161.183 118.546 147.242 1.00 73.44  ? 973 GLN A CA    1 
ATOM   7075 C C     . GLN A 1 973 ? 161.127 117.363 148.200 1.00 67.36  ? 973 GLN A C     1 
ATOM   7076 O O     . GLN A 1 973 ? 161.801 116.350 147.992 1.00 66.72  ? 973 GLN A O     1 
ATOM   7077 C CB    . GLN A 1 973 ? 160.364 118.246 145.988 1.00 69.16  ? 973 GLN A CB    1 
ATOM   7078 C CG    . GLN A 1 973 ? 158.870 118.162 146.240 1.00 62.44  ? 973 GLN A CG    1 
ATOM   7079 C CD    . GLN A 1 973 ? 158.072 117.984 144.967 1.00 67.03  ? 973 GLN A CD    1 
ATOM   7080 O OE1   . GLN A 1 973 ? 158.503 117.300 144.040 1.00 73.70  ? 973 GLN A OE1   1 
ATOM   7081 N NE2   . GLN A 1 973 ? 156.901 118.607 144.909 1.00 57.45  ? 973 GLN A NE2   1 
ATOM   7082 N N     . ARG A 1 974 ? 160.320 117.497 149.254 1.00 60.71  ? 974 ARG A N     1 
ATOM   7083 C CA    . ARG A 1 974 ? 160.100 116.425 150.212 1.00 57.69  ? 974 ARG A CA    1 
ATOM   7084 C C     . ARG A 1 974 ? 158.664 115.926 150.263 1.00 53.03  ? 974 ARG A C     1 
ATOM   7085 O O     . ARG A 1 974 ? 158.433 114.827 150.778 1.00 54.20  ? 974 ARG A O     1 
ATOM   7086 C CB    . ARG A 1 974 ? 160.514 116.873 151.623 1.00 62.63  ? 974 ARG A CB    1 
ATOM   7087 C CG    . ARG A 1 974 ? 161.993 117.193 151.763 1.00 68.36  ? 974 ARG A CG    1 
ATOM   7088 C CD    . ARG A 1 974 ? 162.340 117.578 153.191 1.00 75.06  ? 974 ARG A CD    1 
ATOM   7089 N NE    . ARG A 1 974 ? 161.735 118.846 153.580 1.00 68.87  ? 974 ARG A NE    1 
ATOM   7090 C CZ    . ARG A 1 974 ? 162.348 120.019 153.505 1.00 67.84  ? 974 ARG A CZ    1 
ATOM   7091 N NH1   . ARG A 1 974 ? 163.585 120.124 153.049 1.00 61.55  ? 974 ARG A NH1   1 
ATOM   7092 N NH2   . ARG A 1 974 ? 161.705 121.114 153.902 1.00 69.68  ? 974 ARG A NH2   1 
ATOM   7093 N N     . VAL A 1 975 ? 157.701 116.688 149.752 1.00 51.31  ? 975 VAL A N     1 
ATOM   7094 C CA    . VAL A 1 975 ? 156.291 116.313 149.767 1.00 41.43  ? 975 VAL A CA    1 
ATOM   7095 C C     . VAL A 1 975 ? 155.761 116.401 148.343 1.00 46.24  ? 975 VAL A C     1 
ATOM   7096 O O     . VAL A 1 975 ? 155.873 117.452 147.700 1.00 54.83  ? 975 VAL A O     1 
ATOM   7097 C CB    . VAL A 1 975 ? 155.465 117.211 150.701 1.00 43.41  ? 975 VAL A CB    1 
ATOM   7098 C CG1   . VAL A 1 975 ? 153.987 116.903 150.561 1.00 37.28  ? 975 VAL A CG1   1 
ATOM   7099 C CG2   . VAL A 1 975 ? 155.918 117.038 152.140 1.00 48.74  ? 975 VAL A CG2   1 
ATOM   7100 N N     . LEU A 1 976 ? 155.189 115.306 147.854 1.00 38.32  ? 976 LEU A N     1 
ATOM   7101 C CA    . LEU A 1 976 ? 154.572 115.254 146.537 1.00 28.73  ? 976 LEU A CA    1 
ATOM   7102 C C     . LEU A 1 976 ? 153.062 115.252 146.703 1.00 25.73  ? 976 LEU A C     1 
ATOM   7103 O O     . LEU A 1 976 ? 152.513 114.417 147.428 1.00 31.99  ? 976 LEU A O     1 
ATOM   7104 C CB    . LEU A 1 976 ? 155.020 114.010 145.771 1.00 27.62  ? 976 LEU A CB    1 
ATOM   7105 C CG    . LEU A 1 976 ? 156.332 114.037 144.986 1.00 39.00  ? 976 LEU A CG    1 
ATOM   7106 C CD1   . LEU A 1 976 ? 157.519 114.430 145.855 1.00 49.17  ? 976 LEU A CD1   1 
ATOM   7107 C CD2   . LEU A 1 976 ? 156.571 112.680 144.342 1.00 40.20  ? 976 LEU A CD2   1 
ATOM   7108 N N     . VAL A 1 977 ? 152.393 116.183 146.039 1.00 23.84  ? 977 VAL A N     1 
ATOM   7109 C CA    . VAL A 1 977 ? 150.946 116.314 146.122 1.00 27.04  ? 977 VAL A CA    1 
ATOM   7110 C C     . VAL A 1 977 ? 150.359 115.561 144.933 1.00 30.16  ? 977 VAL A C     1 
ATOM   7111 O O     . VAL A 1 977 ? 150.470 116.000 143.785 1.00 31.52  ? 977 VAL A O     1 
ATOM   7112 C CB    . VAL A 1 977 ? 150.511 117.779 146.149 1.00 34.11  ? 977 VAL A CB    1 
ATOM   7113 C CG1   . VAL A 1 977 ? 149.000 117.877 146.205 1.00 32.83  ? 977 VAL A CG1   1 
ATOM   7114 C CG2   . VAL A 1 977 ? 151.137 118.479 147.339 1.00 33.50  ? 977 VAL A CG2   1 
ATOM   7115 N N     . LEU A 1 978 ? 149.739 114.417 145.209 1.00 22.21  ? 978 LEU A N     1 
ATOM   7116 C CA    . LEU A 1 978 ? 149.138 113.576 144.186 1.00 16.31  ? 978 LEU A CA    1 
ATOM   7117 C C     . LEU A 1 978 ? 147.620 113.661 144.276 1.00 20.09  ? 978 LEU A C     1 
ATOM   7118 O O     . LEU A 1 978 ? 147.059 113.773 145.368 1.00 23.36  ? 978 LEU A O     1 
ATOM   7119 C CB    . LEU A 1 978 ? 149.607 112.125 144.334 1.00 19.76  ? 978 LEU A CB    1 
ATOM   7120 C CG    . LEU A 1 978 ? 151.125 111.915 144.327 1.00 21.49  ? 978 LEU A CG    1 
ATOM   7121 C CD1   . LEU A 1 978 ? 151.486 110.440 144.418 1.00 21.63  ? 978 LEU A CD1   1 
ATOM   7122 C CD2   . LEU A 1 978 ? 151.747 112.539 143.094 1.00 26.83  ? 978 LEU A CD2   1 
ATOM   7123 N N     . GLU A 1 979 ? 146.963 113.629 143.121 1.00 24.94  ? 979 GLU A N     1 
ATOM   7124 C CA    . GLU A 1 979 ? 145.515 113.757 143.018 1.00 22.40  ? 979 GLU A CA    1 
ATOM   7125 C C     . GLU A 1 979 ? 144.905 112.380 142.799 1.00 22.77  ? 979 GLU A C     1 
ATOM   7126 O O     . GLU A 1 979 ? 145.375 111.618 141.949 1.00 26.72  ? 979 GLU A O     1 
ATOM   7127 C CB    . GLU A 1 979 ? 145.144 114.701 141.873 1.00 25.62  ? 979 GLU A CB    1 
ATOM   7128 C CG    . GLU A 1 979 ? 143.665 115.030 141.756 1.00 32.40  ? 979 GLU A CG    1 
ATOM   7129 C CD    . GLU A 1 979 ? 143.419 116.295 140.951 1.00 43.27  ? 979 GLU A CD    1 
ATOM   7130 O OE1   . GLU A 1 979 ? 143.934 117.363 141.343 1.00 50.28  ? 979 GLU A OE1   1 
ATOM   7131 O OE2   . GLU A 1 979 ? 142.722 116.225 139.919 1.00 43.11  ? 979 GLU A OE2   1 
ATOM   7132 N N     . LEU A 1 980 ? 143.861 112.067 143.562 1.00 23.29  ? 980 LEU A N     1 
ATOM   7133 C CA    . LEU A 1 980 ? 143.284 110.732 143.591 1.00 21.59  ? 980 LEU A CA    1 
ATOM   7134 C C     . LEU A 1 980 ? 141.827 110.749 143.153 1.00 23.14  ? 980 LEU A C     1 
ATOM   7135 O O     . LEU A 1 980 ? 141.088 111.700 143.424 1.00 31.99  ? 980 LEU A O     1 
ATOM   7136 C CB    . LEU A 1 980 ? 143.362 110.114 144.991 1.00 21.10  ? 980 LEU A CB    1 
ATOM   7137 C CG    . LEU A 1 980 ? 144.700 109.582 145.499 1.00 23.18  ? 980 LEU A CG    1 
ATOM   7138 C CD1   . LEU A 1 980 ? 145.691 110.707 145.725 1.00 21.66  ? 980 LEU A CD1   1 
ATOM   7139 C CD2   . LEU A 1 980 ? 144.490 108.791 146.778 1.00 25.58  ? 980 LEU A CD2   1 
ATOM   7140 N N     . GLY A 1 981 ? 141.433 109.683 142.474 1.00 18.45  ? 981 GLY A N     1 
ATOM   7141 C CA    . GLY A 1 981 ? 140.032 109.405 142.197 1.00 17.69  ? 981 GLY A CA    1 
ATOM   7142 C C     . GLY A 1 981 ? 139.705 107.970 142.561 1.00 20.69  ? 981 GLY A C     1 
ATOM   7143 O O     . GLY A 1 981 ? 140.454 107.054 142.215 1.00 24.28  ? 981 GLY A O     1 
ATOM   7144 N N     . TYR A 1 982 ? 138.572 107.782 143.233 1.00 21.57  ? 982 TYR A N     1 
ATOM   7145 C CA    . TYR A 1 982 ? 138.124 106.491 143.741 1.00 22.09  ? 982 TYR A CA    1 
ATOM   7146 C C     . TYR A 1 982 ? 136.966 105.956 142.905 1.00 26.90  ? 982 TYR A C     1 
ATOM   7147 O O     . TYR A 1 982 ? 136.442 106.626 142.013 1.00 29.33  ? 982 TYR A O     1 
ATOM   7148 C CB    . TYR A 1 982 ? 137.691 106.599 145.210 1.00 22.57  ? 982 TYR A CB    1 
ATOM   7149 C CG    . TYR A 1 982 ? 138.729 107.179 146.139 1.00 22.61  ? 982 TYR A CG    1 
ATOM   7150 C CD1   . TYR A 1 982 ? 140.038 106.723 146.127 1.00 28.80  ? 982 TYR A CD1   1 
ATOM   7151 C CD2   . TYR A 1 982 ? 138.396 108.181 147.034 1.00 21.39  ? 982 TYR A CD2   1 
ATOM   7152 C CE1   . TYR A 1 982 ? 140.983 107.255 146.980 1.00 29.22  ? 982 TYR A CE1   1 
ATOM   7153 C CE2   . TYR A 1 982 ? 139.331 108.718 147.885 1.00 25.41  ? 982 TYR A CE2   1 
ATOM   7154 C CZ    . TYR A 1 982 ? 140.623 108.254 147.853 1.00 29.53  ? 982 TYR A CZ    1 
ATOM   7155 O OH    . TYR A 1 982 ? 141.561 108.792 148.704 1.00 42.06  ? 982 TYR A OH    1 
ATOM   7156 N N     . GLU A 1 983 ? 136.574 104.721 143.210 1.00 29.75  ? 983 GLU A N     1 
ATOM   7157 C CA    . GLU A 1 983 ? 135.486 104.070 142.493 1.00 28.96  ? 983 GLU A CA    1 
ATOM   7158 C C     . GLU A 1 983 ? 134.154 104.752 142.781 1.00 29.30  ? 983 GLU A C     1 
ATOM   7159 O O     . GLU A 1 983 ? 133.893 105.218 143.892 1.00 33.34  ? 983 GLU A O     1 
ATOM   7160 C CB    . GLU A 1 983 ? 135.414 102.589 142.872 1.00 37.96  ? 983 GLU A CB    1 
ATOM   7161 C CG    . GLU A 1 983 ? 135.318 102.319 144.372 1.00 48.42  ? 983 GLU A CG    1 
ATOM   7162 C CD    . GLU A 1 983 ? 133.891 102.298 144.884 1.00 50.03  ? 983 GLU A CD    1 
ATOM   7163 O OE1   . GLU A 1 983 ? 132.961 102.210 144.056 1.00 51.85  ? 983 GLU A OE1   1 
ATOM   7164 O OE2   . GLU A 1 983 ? 133.698 102.360 146.116 1.00 45.93  ? 983 GLU A OE2   1 
ATOM   7165 N N     . GLY A 1 984 ? 133.306 104.809 141.757 1.00 30.34  ? 984 GLY A N     1 
ATOM   7166 C CA    . GLY A 1 984 ? 131.975 105.362 141.910 1.00 34.50  ? 984 GLY A CA    1 
ATOM   7167 C C     . GLY A 1 984 ? 131.936 106.837 142.216 1.00 39.97  ? 984 GLY A C     1 
ATOM   7168 O O     . GLY A 1 984 ? 130.924 107.330 142.723 1.00 47.80  ? 984 GLY A O     1 
ATOM   7169 N N     . GLU A 1 985 ? 133.013 107.561 141.922 1.00 36.37  ? 985 GLU A N     1 
ATOM   7170 C CA    . GLU A 1 985 ? 133.068 108.986 142.217 1.00 37.80  ? 985 GLU A CA    1 
ATOM   7171 C C     . GLU A 1 985 ? 132.059 109.760 141.377 1.00 47.74  ? 985 GLU A C     1 
ATOM   7172 O O     . GLU A 1 985 ? 131.958 109.560 140.164 1.00 48.29  ? 985 GLU A O     1 
ATOM   7173 C CB    . GLU A 1 985 ? 134.480 109.515 141.965 1.00 35.25  ? 985 GLU A CB    1 
ATOM   7174 C CG    . GLU A 1 985 ? 135.045 109.139 140.611 1.00 38.90  ? 985 GLU A CG    1 
ATOM   7175 C CD    . GLU A 1 985 ? 136.476 109.593 140.428 1.00 41.96  ? 985 GLU A CD    1 
ATOM   7176 O OE1   . GLU A 1 985 ? 136.991 110.312 141.308 1.00 41.92  ? 985 GLU A OE1   1 
ATOM   7177 O OE2   . GLU A 1 985 ? 137.084 109.228 139.400 1.00 43.05  ? 985 GLU A OE2   1 
ATOM   7178 N N     . GLU A 1 986 ? 131.298 110.633 142.035 1.00 57.20  ? 986 GLU A N     1 
ATOM   7179 C CA    . GLU A 1 986 ? 130.463 111.588 141.321 1.00 60.71  ? 986 GLU A CA    1 
ATOM   7180 C C     . GLU A 1 986 ? 131.349 112.600 140.602 1.00 60.90  ? 986 GLU A C     1 
ATOM   7181 O O     . GLU A 1 986 ? 132.491 112.847 140.999 1.00 59.44  ? 986 GLU A O     1 
ATOM   7182 C CB    . GLU A 1 986 ? 129.509 112.293 142.291 1.00 61.34  ? 986 GLU A CB    1 
ATOM   7183 C CG    . GLU A 1 986 ? 128.320 112.994 141.635 1.00 75.04  ? 986 GLU A CG    1 
ATOM   7184 C CD    . GLU A 1 986 ? 127.294 113.491 142.647 1.00 88.44  ? 986 GLU A CD    1 
ATOM   7185 O OE1   . GLU A 1 986 ? 127.569 113.423 143.864 1.00 87.50  ? 986 GLU A OE1   1 
ATOM   7186 O OE2   . GLU A 1 986 ? 126.208 113.947 142.224 1.00 93.84  ? 986 GLU A OE2   1 
ATOM   7187 N N     . ASP A 1 987 ? 130.821 113.178 139.526 1.00 63.43  ? 987 ASP A N     1 
ATOM   7188 C CA    . ASP A 1 987 ? 131.628 114.054 138.686 1.00 67.75  ? 987 ASP A CA    1 
ATOM   7189 C C     . ASP A 1 987 ? 132.157 115.243 139.481 1.00 65.29  ? 987 ASP A C     1 
ATOM   7190 O O     . ASP A 1 987 ? 131.470 115.790 140.348 1.00 66.25  ? 987 ASP A O     1 
ATOM   7191 C CB    . ASP A 1 987 ? 130.808 114.544 137.492 1.00 72.89  ? 987 ASP A CB    1 
ATOM   7192 C CG    . ASP A 1 987 ? 130.486 113.435 136.514 1.00 80.81  ? 987 ASP A CG    1 
ATOM   7193 O OD1   . ASP A 1 987 ? 131.293 112.488 136.403 1.00 79.89  ? 987 ASP A OD1   1 
ATOM   7194 O OD2   . ASP A 1 987 ? 129.428 113.509 135.855 1.00 87.68  ? 987 ASP A OD2   1 
ATOM   7195 N N     . ASP A 1 988 ? 133.401 115.621 139.192 1.00 60.02  ? 988 ASP A N     1 
ATOM   7196 C CA    . ASP A 1 988 ? 134.064 116.802 139.737 1.00 60.15  ? 988 ASP A CA    1 
ATOM   7197 C C     . ASP A 1 988 ? 134.309 116.719 141.240 1.00 58.68  ? 988 ASP A C     1 
ATOM   7198 O O     . ASP A 1 988 ? 134.648 117.735 141.861 1.00 61.92  ? 988 ASP A O     1 
ATOM   7199 C CB    . ASP A 1 988 ? 133.280 118.085 139.418 1.00 67.07  ? 988 ASP A CB    1 
ATOM   7200 C CG    . ASP A 1 988 ? 133.180 118.360 137.930 1.00 74.33  ? 988 ASP A CG    1 
ATOM   7201 O OD1   . ASP A 1 988 ? 133.505 117.464 137.121 1.00 77.87  ? 988 ASP A OD1   1 
ATOM   7202 O OD2   . ASP A 1 988 ? 132.782 119.486 137.570 1.00 70.14  ? 988 ASP A OD2   1 
ATOM   7203 N N     . THR A 1 989 ? 134.146 115.544 141.848 1.00 54.85  ? 989 THR A N     1 
ATOM   7204 C CA    . THR A 1 989 ? 134.446 115.393 143.269 1.00 43.82  ? 989 THR A CA    1 
ATOM   7205 C C     . THR A 1 989 ? 135.939 115.564 143.511 1.00 39.79  ? 989 THR A C     1 
ATOM   7206 O O     . THR A 1 989 ? 136.758 114.854 142.921 1.00 41.25  ? 989 THR A O     1 
ATOM   7207 C CB    . THR A 1 989 ? 133.981 114.029 143.778 1.00 34.63  ? 989 THR A CB    1 
ATOM   7208 O OG1   . THR A 1 989 ? 132.562 113.917 143.624 1.00 44.82  ? 989 THR A OG1   1 
ATOM   7209 C CG2   . THR A 1 989 ? 134.322 113.872 145.245 1.00 28.00  ? 989 THR A CG2   1 
ATOM   7210 N N     . ASN A 1 990 ? 136.291 116.504 144.383 1.00 37.40  ? 990 ASN A N     1 
ATOM   7211 C CA    . ASN A 1 990 ? 137.686 116.794 144.716 1.00 32.66  ? 990 ASN A CA    1 
ATOM   7212 C C     . ASN A 1 990 ? 138.060 116.025 145.980 1.00 30.05  ? 990 ASN A C     1 
ATOM   7213 O O     . ASN A 1 990 ? 137.862 116.494 147.101 1.00 29.53  ? 990 ASN A O     1 
ATOM   7214 C CB    . ASN A 1 990 ? 137.903 118.293 144.874 1.00 37.34  ? 990 ASN A CB    1 
ATOM   7215 C CG    . ASN A 1 990 ? 138.302 118.963 143.572 1.00 46.25  ? 990 ASN A CG    1 
ATOM   7216 O OD1   . ASN A 1 990 ? 139.461 119.330 143.381 1.00 49.32  ? 990 ASN A OD1   1 
ATOM   7217 N ND2   . ASN A 1 990 ? 137.346 119.114 142.664 1.00 52.14  ? 990 ASN A ND2   1 
ATOM   7218 N N     . PHE A 1 991 ? 138.605 114.829 145.788 1.00 27.50  ? 991 PHE A N     1 
ATOM   7219 C CA    . PHE A 1 991 ? 139.063 114.011 146.894 1.00 25.20  ? 991 PHE A CA    1 
ATOM   7220 C C     . PHE A 1 991 ? 140.326 114.601 147.520 1.00 23.62  ? 991 PHE A C     1 
ATOM   7221 O O     . PHE A 1 991 ? 141.067 115.337 146.867 1.00 24.80  ? 991 PHE A O     1 
ATOM   7222 C CB    . PHE A 1 991 ? 139.315 112.590 146.407 1.00 23.44  ? 991 PHE A CB    1 
ATOM   7223 C CG    . PHE A 1 991 ? 138.064 111.790 146.211 1.00 20.25  ? 991 PHE A CG    1 
ATOM   7224 C CD1   . PHE A 1 991 ? 137.109 111.724 147.207 1.00 18.24  ? 991 PHE A CD1   1 
ATOM   7225 C CD2   . PHE A 1 991 ? 137.842 111.107 145.033 1.00 21.12  ? 991 PHE A CD2   1 
ATOM   7226 C CE1   . PHE A 1 991 ? 135.964 110.988 147.032 1.00 19.34  ? 991 PHE A CE1   1 
ATOM   7227 C CE2   . PHE A 1 991 ? 136.697 110.370 144.855 1.00 23.83  ? 991 PHE A CE2   1 
ATOM   7228 C CZ    . PHE A 1 991 ? 135.758 110.311 145.853 1.00 22.08  ? 991 PHE A CZ    1 
ATOM   7229 N N     . PRO A 1 992 ? 140.587 114.296 148.795 1.00 23.53  ? 992 PRO A N     1 
ATOM   7230 C CA    . PRO A 1 992 ? 141.777 114.848 149.455 1.00 17.98  ? 992 PRO A CA    1 
ATOM   7231 C C     . PRO A 1 992 ? 143.053 114.450 148.733 1.00 19.60  ? 992 PRO A C     1 
ATOM   7232 O O     . PRO A 1 992 ? 143.199 113.320 148.263 1.00 24.39  ? 992 PRO A O     1 
ATOM   7233 C CB    . PRO A 1 992 ? 141.721 114.237 150.859 1.00 22.00  ? 992 PRO A CB    1 
ATOM   7234 C CG    . PRO A 1 992 ? 140.312 113.875 151.065 1.00 23.74  ? 992 PRO A CG    1 
ATOM   7235 C CD    . PRO A 1 992 ? 139.761 113.506 149.724 1.00 25.77  ? 992 PRO A CD    1 
ATOM   7236 N N     . ARG A 1 993 ? 143.981 115.395 148.649 1.00 16.55  ? 993 ARG A N     1 
ATOM   7237 C CA    . ARG A 1 993 ? 145.247 115.147 147.982 1.00 14.96  ? 993 ARG A CA    1 
ATOM   7238 C C     . ARG A 1 993 ? 146.140 114.280 148.856 1.00 14.46  ? 993 ARG A C     1 
ATOM   7239 O O     . ARG A 1 993 ? 146.140 114.397 150.082 1.00 17.85  ? 993 ARG A O     1 
ATOM   7240 C CB    . ARG A 1 993 ? 145.950 116.462 147.652 1.00 20.71  ? 993 ARG A CB    1 
ATOM   7241 C CG    . ARG A 1 993 ? 145.164 117.385 146.729 1.00 26.51  ? 993 ARG A CG    1 
ATOM   7242 C CD    . ARG A 1 993 ? 144.681 116.658 145.483 1.00 29.23  ? 993 ARG A CD    1 
ATOM   7243 N NE    . ARG A 1 993 ? 144.113 117.566 144.492 1.00 37.49  ? 993 ARG A NE    1 
ATOM   7244 C CZ    . ARG A 1 993 ? 142.853 117.982 144.489 1.00 37.70  ? 993 ARG A CZ    1 
ATOM   7245 N NH1   . ARG A 1 993 ? 142.003 117.620 145.434 1.00 43.68  ? 993 ARG A NH1   1 
ATOM   7246 N NH2   . ARG A 1 993 ? 142.435 118.779 143.510 1.00 30.02  ? 993 ARG A NH2   1 
ATOM   7247 N N     . LEU A 1 994 ? 146.894 113.397 148.214 1.00 15.76  ? 994 LEU A N     1 
ATOM   7248 C CA    . LEU A 1 994 ? 147.864 112.570 148.913 1.00 17.64  ? 994 LEU A CA    1 
ATOM   7249 C C     . LEU A 1 994 ? 149.178 113.329 149.029 1.00 27.27  ? 994 LEU A C     1 
ATOM   7250 O O     . LEU A 1 994 ? 149.807 113.651 148.016 1.00 29.05  ? 994 LEU A O     1 
ATOM   7251 C CB    . LEU A 1 994 ? 148.069 111.254 148.174 1.00 17.94  ? 994 LEU A CB    1 
ATOM   7252 C CG    . LEU A 1 994 ? 148.985 110.224 148.825 1.00 24.13  ? 994 LEU A CG    1 
ATOM   7253 C CD1   . LEU A 1 994 ? 148.309 109.598 150.026 1.00 31.09  ? 994 LEU A CD1   1 
ATOM   7254 C CD2   . LEU A 1 994 ? 149.381 109.173 147.817 1.00 24.18  ? 994 LEU A CD2   1 
ATOM   7255 N N     . HIS A 1 995 ? 149.580 113.626 150.262 1.00 28.41  ? 995 HIS A N     1 
ATOM   7256 C CA    . HIS A 1 995 ? 150.878 114.236 150.533 1.00 22.26  ? 995 HIS A CA    1 
ATOM   7257 C C     . HIS A 1 995 ? 151.915 113.133 150.731 1.00 20.99  ? 995 HIS A C     1 
ATOM   7258 O O     . HIS A 1 995 ? 152.366 112.832 151.837 1.00 29.45  ? 995 HIS A O     1 
ATOM   7259 C CB    . HIS A 1 995 ? 150.790 115.166 151.734 1.00 23.97  ? 995 HIS A CB    1 
ATOM   7260 C CG    . HIS A 1 995 ? 150.109 116.463 151.435 1.00 27.73  ? 995 HIS A CG    1 
ATOM   7261 N ND1   . HIS A 1 995 ? 148.742 116.574 151.312 1.00 27.90  ? 995 HIS A ND1   1 
ATOM   7262 C CD2   . HIS A 1 995 ? 150.608 117.700 151.205 1.00 34.27  ? 995 HIS A CD2   1 
ATOM   7263 C CE1   . HIS A 1 995 ? 148.426 117.826 151.036 1.00 35.29  ? 995 HIS A CE1   1 
ATOM   7264 N NE2   . HIS A 1 995 ? 149.540 118.530 150.963 1.00 35.27  ? 995 HIS A NE2   1 
ATOM   7265 N N     . TYR A 1 996 ? 152.279 112.521 149.609 1.00 18.25  ? 996 TYR A N     1 
ATOM   7266 C CA    . TYR A 1 996 ? 153.279 111.466 149.578 1.00 21.03  ? 996 TYR A CA    1 
ATOM   7267 C C     . TYR A 1 996 ? 154.612 112.017 150.066 1.00 34.30  ? 996 TYR A C     1 
ATOM   7268 O O     . TYR A 1 996 ? 155.209 112.881 149.417 1.00 46.77  ? 996 TYR A O     1 
ATOM   7269 C CB    . TYR A 1 996 ? 153.381 110.909 148.158 1.00 26.09  ? 996 TYR A CB    1 
ATOM   7270 C CG    . TYR A 1 996 ? 154.287 109.718 147.977 1.00 34.86  ? 996 TYR A CG    1 
ATOM   7271 C CD1   . TYR A 1 996 ? 153.884 108.452 148.362 1.00 33.18  ? 996 TYR A CD1   1 
ATOM   7272 C CD2   . TYR A 1 996 ? 155.534 109.855 147.381 1.00 41.13  ? 996 TYR A CD2   1 
ATOM   7273 C CE1   . TYR A 1 996 ? 154.703 107.358 148.183 1.00 39.20  ? 996 TYR A CE1   1 
ATOM   7274 C CE2   . TYR A 1 996 ? 156.361 108.766 147.196 1.00 39.38  ? 996 TYR A CE2   1 
ATOM   7275 C CZ    . TYR A 1 996 ? 155.937 107.519 147.599 1.00 41.18  ? 996 TYR A CZ    1 
ATOM   7276 O OH    . TYR A 1 996 ? 156.751 106.425 147.423 1.00 47.38  ? 996 TYR A OH    1 
ATOM   7277 N N     . LYS A 1 997 ? 155.083 111.535 151.210 1.00 32.06  ? 997 LYS A N     1 
ATOM   7278 C CA    . LYS A 1 997 ? 156.236 112.112 151.884 1.00 34.63  ? 997 LYS A CA    1 
ATOM   7279 C C     . LYS A 1 997 ? 157.470 111.257 151.635 1.00 45.26  ? 997 LYS A C     1 
ATOM   7280 O O     . LYS A 1 997 ? 157.420 110.032 151.777 1.00 48.86  ? 997 LYS A O     1 
ATOM   7281 C CB    . LYS A 1 997 ? 155.973 112.238 153.384 1.00 40.49  ? 997 LYS A CB    1 
ATOM   7282 C CG    . LYS A 1 997 ? 156.975 113.100 154.130 1.00 51.87  ? 997 LYS A CG    1 
ATOM   7283 C CD    . LYS A 1 997 ? 156.724 113.049 155.629 1.00 62.78  ? 997 LYS A CD    1 
ATOM   7284 C CE    . LYS A 1 997 ? 157.528 114.107 156.366 1.00 72.22  ? 997 LYS A CE    1 
ATOM   7285 N NZ    . LYS A 1 997 ? 157.097 115.484 155.996 1.00 78.58  ? 997 LYS A NZ    1 
ATOM   7286 N N     . LEU A 1 998 ? 158.571 111.905 151.270 1.00 50.60  ? 998 LEU A N     1 
ATOM   7287 C CA    . LEU A 1 998 ? 159.841 111.211 151.082 1.00 55.24  ? 998 LEU A CA    1 
ATOM   7288 C C     . LEU A 1 998 ? 160.564 111.026 152.412 1.00 62.20  ? 998 LEU A C     1 
ATOM   7289 O O     . LEU A 1 998 ? 160.446 111.851 153.318 1.00 64.52  ? 998 LEU A O     1 
ATOM   7290 C CB    . LEU A 1 998 ? 160.736 111.973 150.103 1.00 52.05  ? 998 LEU A CB    1 
ATOM   7291 C CG    . LEU A 1 998 ? 160.568 111.678 148.611 1.00 57.18  ? 998 LEU A CG    1 
ATOM   7292 C CD1   . LEU A 1 998 ? 160.805 110.201 148.329 1.00 58.47  ? 998 LEU A CD1   1 
ATOM   7293 C CD2   . LEU A 1 998 ? 159.202 112.108 148.113 1.00 53.15  ? 998 LEU A CD2   1 
ATOM   7294 O OXT   . LEU A 1 998 ? 161.288 110.050 152.611 1.00 63.81  ? 998 LEU A OXT   1 
ATOM   7295 N N     . ALA B 2 3   ? 141.805 119.916 138.425 1.00 45.64  ? 3   ALA B N     1 
ATOM   7296 C CA    . ALA B 2 3   ? 141.007 119.929 137.207 1.00 46.71  ? 3   ALA B CA    1 
ATOM   7297 C C     . ALA B 2 3   ? 141.461 118.833 136.253 1.00 47.85  ? 3   ALA B C     1 
ATOM   7298 O O     . ALA B 2 3   ? 140.703 118.400 135.385 1.00 53.32  ? 3   ALA B O     1 
ATOM   7299 C CB    . ALA B 2 3   ? 141.092 121.287 136.532 1.00 45.18  ? 3   ALA B CB    1 
ATOM   7300 N N     . SER B 2 4   ? 142.710 118.394 136.411 1.00 46.58  ? 4   SER B N     1 
ATOM   7301 C CA    . SER B 2 4   ? 143.266 117.396 135.503 1.00 42.57  ? 4   SER B CA    1 
ATOM   7302 C C     . SER B 2 4   ? 142.518 116.071 135.580 1.00 42.41  ? 4   SER B C     1 
ATOM   7303 O O     . SER B 2 4   ? 142.436 115.345 134.585 1.00 46.24  ? 4   SER B O     1 
ATOM   7304 C CB    . SER B 2 4   ? 144.752 117.195 135.790 1.00 44.90  ? 4   SER B CB    1 
ATOM   7305 O OG    . SER B 2 4   ? 145.487 118.347 135.421 1.00 47.87  ? 4   SER B OG    1 
ATOM   7306 N N     . LYS B 2 5   ? 141.992 115.723 136.759 1.00 35.87  ? 5   LYS B N     1 
ATOM   7307 C CA    . LYS B 2 5   ? 141.303 114.444 136.915 1.00 35.57  ? 5   LYS B CA    1 
ATOM   7308 C C     . LYS B 2 5   ? 140.035 114.366 136.073 1.00 40.57  ? 5   LYS B C     1 
ATOM   7309 O O     . LYS B 2 5   ? 139.744 113.315 135.489 1.00 45.50  ? 5   LYS B O     1 
ATOM   7310 C CB    . LYS B 2 5   ? 140.971 114.206 138.386 1.00 33.85  ? 5   LYS B CB    1 
ATOM   7311 C CG    . LYS B 2 5   ? 140.768 112.751 138.737 1.00 25.09  ? 5   LYS B CG    1 
ATOM   7312 C CD    . LYS B 2 5   ? 139.373 112.511 139.246 1.00 16.75  ? 5   LYS B CD    1 
ATOM   7313 C CE    . LYS B 2 5   ? 139.099 113.349 140.473 1.00 19.75  ? 5   LYS B CE    1 
ATOM   7314 N NZ    . LYS B 2 5   ? 137.782 113.019 141.060 1.00 29.14  ? 5   LYS B NZ    1 
ATOM   7315 N N     . ARG B 2 6   ? 139.265 115.455 136.002 1.00 38.94  ? 6   ARG B N     1 
ATOM   7316 C CA    . ARG B 2 6   ? 138.083 115.473 135.144 1.00 36.14  ? 6   ARG B CA    1 
ATOM   7317 C C     . ARG B 2 6   ? 138.472 115.332 133.678 1.00 37.46  ? 6   ARG B C     1 
ATOM   7318 O O     . ARG B 2 6   ? 137.839 114.584 132.924 1.00 43.60  ? 6   ARG B O     1 
ATOM   7319 C CB    . ARG B 2 6   ? 137.280 116.754 135.366 1.00 30.12  ? 6   ARG B CB    1 
ATOM   7320 C CG    . ARG B 2 6   ? 136.201 116.967 134.319 1.00 42.55  ? 6   ARG B CG    1 
ATOM   7321 C CD    . ARG B 2 6   ? 135.311 118.159 134.622 1.00 53.25  ? 6   ARG B CD    1 
ATOM   7322 N NE    . ARG B 2 6   ? 134.412 118.433 133.508 1.00 61.23  ? 6   ARG B NE    1 
ATOM   7323 C CZ    . ARG B 2 6   ? 133.374 119.256 133.556 1.00 68.62  ? 6   ARG B CZ    1 
ATOM   7324 N NH1   . ARG B 2 6   ? 133.033 119.877 134.674 1.00 71.89  ? 6   ARG B NH1   1 
ATOM   7325 N NH2   . ARG B 2 6   ? 132.660 119.460 132.454 1.00 66.17  ? 6   ARG B NH2   1 
ATOM   7326 N N     . VAL B 2 7   ? 139.514 116.051 133.257 1.00 36.05  ? 7   VAL B N     1 
ATOM   7327 C CA    . VAL B 2 7   ? 140.001 115.934 131.887 1.00 34.89  ? 7   VAL B CA    1 
ATOM   7328 C C     . VAL B 2 7   ? 140.445 114.508 131.588 1.00 39.38  ? 7   VAL B C     1 
ATOM   7329 O O     . VAL B 2 7   ? 140.206 113.993 130.489 1.00 47.15  ? 7   VAL B O     1 
ATOM   7330 C CB    . VAL B 2 7   ? 141.137 116.947 131.645 1.00 37.54  ? 7   VAL B CB    1 
ATOM   7331 C CG1   . VAL B 2 7   ? 141.634 116.865 130.213 1.00 42.57  ? 7   VAL B CG1   1 
ATOM   7332 C CG2   . VAL B 2 7   ? 140.663 118.351 131.975 1.00 41.91  ? 7   VAL B CG2   1 
ATOM   7333 N N     . ALA B 2 8   ? 141.082 113.844 132.557 1.00 35.77  ? 8   ALA B N     1 
ATOM   7334 C CA    . ALA B 2 8   ? 141.479 112.450 132.381 1.00 36.16  ? 8   ALA B CA    1 
ATOM   7335 C C     . ALA B 2 8   ? 140.267 111.532 132.272 1.00 39.70  ? 8   ALA B C     1 
ATOM   7336 O O     . ALA B 2 8   ? 140.263 110.602 131.461 1.00 43.99  ? 8   ALA B O     1 
ATOM   7337 C CB    . ALA B 2 8   ? 142.382 112.012 133.533 1.00 39.81  ? 8   ALA B CB    1 
ATOM   7338 N N     . LYS B 2 9   ? 139.236 111.767 133.086 1.00 40.01  ? 9   LYS B N     1 
ATOM   7339 C CA    . LYS B 2 9   ? 138.014 110.974 132.967 1.00 40.13  ? 9   LYS B CA    1 
ATOM   7340 C C     . LYS B 2 9   ? 137.371 111.148 131.595 1.00 46.51  ? 9   LYS B C     1 
ATOM   7341 O O     . LYS B 2 9   ? 136.895 110.176 130.996 1.00 49.05  ? 9   LYS B O     1 
ATOM   7342 C CB    . LYS B 2 9   ? 137.018 111.348 134.065 1.00 38.38  ? 9   LYS B CB    1 
ATOM   7343 C CG    . LYS B 2 9   ? 137.405 110.910 135.464 1.00 41.69  ? 9   LYS B CG    1 
ATOM   7344 C CD    . LYS B 2 9   ? 136.207 110.340 136.214 1.00 50.70  ? 9   LYS B CD    1 
ATOM   7345 C CE    . LYS B 2 9   ? 134.986 111.251 136.127 1.00 56.83  ? 9   LYS B CE    1 
ATOM   7346 N NZ    . LYS B 2 9   ? 133.776 110.635 136.750 1.00 65.07  ? 9   LYS B NZ    1 
ATOM   7347 N N     . GLU B 2 10  ? 137.337 112.385 131.087 1.00 44.16  ? 10  GLU B N     1 
ATOM   7348 C CA    . GLU B 2 10  ? 136.768 112.633 129.764 1.00 37.14  ? 10  GLU B CA    1 
ATOM   7349 C C     . GLU B 2 10  ? 137.595 111.970 128.670 1.00 39.11  ? 10  GLU B C     1 
ATOM   7350 O O     . GLU B 2 10  ? 137.043 111.355 127.745 1.00 44.58  ? 10  GLU B O     1 
ATOM   7351 C CB    . GLU B 2 10  ? 136.649 114.133 129.516 1.00 36.74  ? 10  GLU B CB    1 
ATOM   7352 C CG    . GLU B 2 10  ? 135.809 114.842 130.547 1.00 46.08  ? 10  GLU B CG    1 
ATOM   7353 C CD    . GLU B 2 10  ? 135.551 116.284 130.194 1.00 58.53  ? 10  GLU B CD    1 
ATOM   7354 O OE1   . GLU B 2 10  ? 135.602 116.618 128.994 1.00 63.96  ? 10  GLU B OE1   1 
ATOM   7355 O OE2   . GLU B 2 10  ? 135.298 117.085 131.117 1.00 58.72  ? 10  GLU B OE2   1 
ATOM   7356 N N     . LEU B 2 11  ? 138.920 112.064 128.774 1.00 40.01  ? 11  LEU B N     1 
ATOM   7357 C CA    . LEU B 2 11  ? 139.798 111.401 127.819 1.00 39.81  ? 11  LEU B CA    1 
ATOM   7358 C C     . LEU B 2 11  ? 139.617 109.888 127.861 1.00 40.54  ? 11  LEU B C     1 
ATOM   7359 O O     . LEU B 2 11  ? 139.710 109.219 126.828 1.00 48.36  ? 11  LEU B O     1 
ATOM   7360 C CB    . LEU B 2 11  ? 141.247 111.782 128.104 1.00 36.53  ? 11  LEU B CB    1 
ATOM   7361 C CG    . LEU B 2 11  ? 142.304 111.269 127.136 1.00 37.64  ? 11  LEU B CG    1 
ATOM   7362 C CD1   . LEU B 2 11  ? 142.157 111.932 125.780 1.00 39.31  ? 11  LEU B CD1   1 
ATOM   7363 C CD2   . LEU B 2 11  ? 143.689 111.516 127.714 1.00 41.83  ? 11  LEU B CD2   1 
ATOM   7364 N N     . GLU B 2 12  ? 139.366 109.333 129.049 1.00 42.61  ? 12  GLU B N     1 
ATOM   7365 C CA    . GLU B 2 12  ? 139.111 107.902 129.169 1.00 44.18  ? 12  GLU B CA    1 
ATOM   7366 C C     . GLU B 2 12  ? 137.789 107.516 128.518 1.00 44.86  ? 12  GLU B C     1 
ATOM   7367 O O     . GLU B 2 12  ? 137.728 106.555 127.742 1.00 47.14  ? 12  GLU B O     1 
ATOM   7368 C CB    . GLU B 2 12  ? 139.124 107.486 130.641 1.00 48.48  ? 12  GLU B CB    1 
ATOM   7369 C CG    . GLU B 2 12  ? 140.506 107.407 131.274 1.00 52.03  ? 12  GLU B CG    1 
ATOM   7370 C CD    . GLU B 2 12  ? 141.269 106.152 130.883 1.00 60.45  ? 12  GLU B CD    1 
ATOM   7371 O OE1   . GLU B 2 12  ? 141.277 105.792 129.686 1.00 53.66  ? 12  GLU B OE1   1 
ATOM   7372 O OE2   . GLU B 2 12  ? 141.863 105.518 131.781 1.00 63.60  ? 12  GLU B OE2   1 
ATOM   7373 N N     . ASP B 2 13  ? 136.716 108.253 128.818 1.00 44.23  ? 13  ASP B N     1 
ATOM   7374 C CA    . ASP B 2 13  ? 135.430 107.889 128.233 1.00 47.55  ? 13  ASP B CA    1 
ATOM   7375 C C     . ASP B 2 13  ? 135.400 108.123 126.728 1.00 49.08  ? 13  ASP B C     1 
ATOM   7376 O O     . ASP B 2 13  ? 134.551 107.539 126.043 1.00 54.92  ? 13  ASP B O     1 
ATOM   7377 C CB    . ASP B 2 13  ? 134.266 108.624 128.927 1.00 46.79  ? 13  ASP B CB    1 
ATOM   7378 C CG    . ASP B 2 13  ? 134.350 110.136 128.821 1.00 46.55  ? 13  ASP B CG    1 
ATOM   7379 O OD1   . ASP B 2 13  ? 134.307 110.684 127.698 1.00 46.23  ? 13  ASP B OD1   1 
ATOM   7380 O OD2   . ASP B 2 13  ? 134.398 110.783 129.889 1.00 45.33  ? 13  ASP B OD2   1 
ATOM   7381 N N     . LEU B 2 14  ? 136.322 108.928 126.198 1.00 43.35  ? 14  LEU B N     1 
ATOM   7382 C CA    . LEU B 2 14  ? 136.422 109.097 124.753 1.00 44.24  ? 14  LEU B CA    1 
ATOM   7383 C C     . LEU B 2 14  ? 137.322 108.050 124.099 1.00 44.55  ? 14  LEU B C     1 
ATOM   7384 O O     . LEU B 2 14  ? 136.991 107.533 123.027 1.00 51.11  ? 14  LEU B O     1 
ATOM   7385 C CB    . LEU B 2 14  ? 136.918 110.506 124.424 1.00 42.76  ? 14  LEU B CB    1 
ATOM   7386 C CG    . LEU B 2 14  ? 135.832 111.570 124.293 1.00 46.24  ? 14  LEU B CG    1 
ATOM   7387 C CD1   . LEU B 2 14  ? 136.449 112.940 124.048 1.00 51.54  ? 14  LEU B CD1   1 
ATOM   7388 C CD2   . LEU B 2 14  ? 134.881 111.199 123.169 1.00 47.83  ? 14  LEU B CD2   1 
ATOM   7389 N N     . GLN B 2 15  ? 138.470 107.743 124.708 1.00 39.76  ? 15  GLN B N     1 
ATOM   7390 C CA    . GLN B 2 15  ? 139.347 106.712 124.159 1.00 37.89  ? 15  GLN B CA    1 
ATOM   7391 C C     . GLN B 2 15  ? 138.701 105.332 124.200 1.00 41.83  ? 15  GLN B C     1 
ATOM   7392 O O     . GLN B 2 15  ? 138.903 104.526 123.285 1.00 45.18  ? 15  GLN B O     1 
ATOM   7393 C CB    . GLN B 2 15  ? 140.678 106.692 124.910 1.00 38.14  ? 15  GLN B CB    1 
ATOM   7394 C CG    . GLN B 2 15  ? 141.716 107.670 124.385 1.00 38.44  ? 15  GLN B CG    1 
ATOM   7395 C CD    . GLN B 2 15  ? 143.041 107.539 125.105 1.00 33.50  ? 15  GLN B CD    1 
ATOM   7396 O OE1   . GLN B 2 15  ? 143.119 106.934 126.172 1.00 31.66  ? 15  GLN B OE1   1 
ATOM   7397 N NE2   . GLN B 2 15  ? 144.094 108.097 124.523 1.00 36.77  ? 15  GLN B NE2   1 
ATOM   7398 N N     . LYS B 2 16  ? 137.925 105.038 125.245 1.00 46.20  ? 16  LYS B N     1 
ATOM   7399 C CA    . LYS B 2 16  ? 137.277 103.736 125.333 1.00 53.82  ? 16  LYS B CA    1 
ATOM   7400 C C     . LYS B 2 16  ? 136.189 103.558 124.283 1.00 61.20  ? 16  LYS B C     1 
ATOM   7401 O O     . LYS B 2 16  ? 135.899 102.421 123.897 1.00 64.00  ? 16  LYS B O     1 
ATOM   7402 C CB    . LYS B 2 16  ? 136.695 103.530 126.733 1.00 54.76  ? 16  LYS B CB    1 
ATOM   7403 C CG    . LYS B 2 16  ? 137.747 103.339 127.818 1.00 60.26  ? 16  LYS B CG    1 
ATOM   7404 C CD    . LYS B 2 16  ? 137.113 103.073 129.179 1.00 62.81  ? 16  LYS B CD    1 
ATOM   7405 C CE    . LYS B 2 16  ? 136.352 104.286 129.699 1.00 63.06  ? 16  LYS B CE    1 
ATOM   7406 N NZ    . LYS B 2 16  ? 135.819 104.063 131.075 1.00 61.72  ? 16  LYS B NZ    1 
ATOM   7407 N N     . GLU B 2 17  ? 135.577 104.647 123.819 1.00 56.47  ? 17  GLU B N     1 
ATOM   7408 C CA    . GLU B 2 17  ? 134.659 104.579 122.690 1.00 51.01  ? 17  GLU B CA    1 
ATOM   7409 C C     . GLU B 2 17  ? 134.737 105.872 121.890 1.00 54.38  ? 17  GLU B C     1 
ATOM   7410 O O     . GLU B 2 17  ? 134.043 106.845 122.198 1.00 55.75  ? 17  GLU B O     1 
ATOM   7411 C CB    . GLU B 2 17  ? 133.229 104.321 123.169 1.00 54.32  ? 17  GLU B CB    1 
ATOM   7412 C CG    . GLU B 2 17  ? 132.200 104.147 122.055 1.00 62.64  ? 17  GLU B CG    1 
ATOM   7413 C CD    . GLU B 2 17  ? 132.348 102.836 121.301 1.00 70.82  ? 17  GLU B CD    1 
ATOM   7414 O OE1   . GLU B 2 17  ? 133.379 102.638 120.622 1.00 71.66  ? 17  GLU B OE1   1 
ATOM   7415 O OE2   . GLU B 2 17  ? 131.426 101.999 121.386 1.00 77.04  ? 17  GLU B OE2   1 
ATOM   7416 N N     . LEU B 2 18  ? 135.584 105.890 120.865 1.00 55.56  ? 18  LEU B N     1 
ATOM   7417 C CA    . LEU B 2 18  ? 135.734 107.080 120.045 1.00 52.41  ? 18  LEU B CA    1 
ATOM   7418 C C     . LEU B 2 18  ? 134.538 107.237 119.110 1.00 54.07  ? 18  LEU B C     1 
ATOM   7419 O O     . LEU B 2 18  ? 134.050 106.250 118.552 1.00 59.38  ? 18  LEU B O     1 
ATOM   7420 C CB    . LEU B 2 18  ? 137.026 107.017 119.229 1.00 50.93  ? 18  LEU B CB    1 
ATOM   7421 C CG    . LEU B 2 18  ? 138.298 107.491 119.936 1.00 53.88  ? 18  LEU B CG    1 
ATOM   7422 C CD1   . LEU B 2 18  ? 139.523 107.292 119.056 1.00 53.72  ? 18  LEU B CD1   1 
ATOM   7423 C CD2   . LEU B 2 18  ? 138.169 108.949 120.345 1.00 44.47  ? 18  LEU B CD2   1 
ATOM   7424 N N     . PRO B 2 19  ? 134.035 108.456 118.933 1.00 49.34  ? 19  PRO B N     1 
ATOM   7425 C CA    . PRO B 2 19  ? 133.101 108.712 117.834 1.00 51.89  ? 19  PRO B CA    1 
ATOM   7426 C C     . PRO B 2 19  ? 133.766 108.409 116.498 1.00 54.08  ? 19  PRO B C     1 
ATOM   7427 O O     . PRO B 2 19  ? 134.985 108.522 116.351 1.00 55.48  ? 19  PRO B O     1 
ATOM   7428 C CB    . PRO B 2 19  ? 132.774 110.201 117.988 1.00 52.60  ? 19  PRO B CB    1 
ATOM   7429 C CG    . PRO B 2 19  ? 133.011 110.482 119.436 1.00 53.44  ? 19  PRO B CG    1 
ATOM   7430 C CD    . PRO B 2 19  ? 134.193 109.629 119.808 1.00 49.44  ? 19  PRO B CD    1 
ATOM   7431 N N     . LYS B 2 20  ? 132.950 107.998 115.526 1.00 58.42  ? 20  LYS B N     1 
ATOM   7432 C CA    . LYS B 2 20  ? 133.486 107.529 114.251 1.00 62.15  ? 20  LYS B CA    1 
ATOM   7433 C C     . LYS B 2 20  ? 134.300 108.601 113.537 1.00 55.72  ? 20  LYS B C     1 
ATOM   7434 O O     . LYS B 2 20  ? 135.218 108.276 112.776 1.00 53.39  ? 20  LYS B O     1 
ATOM   7435 C CB    . LYS B 2 20  ? 132.351 107.043 113.348 1.00 63.48  ? 20  LYS B CB    1 
ATOM   7436 C CG    . LYS B 2 20  ? 131.795 105.670 113.709 1.00 71.41  ? 20  LYS B CG    1 
ATOM   7437 C CD    . LYS B 2 20  ? 130.843 105.728 114.892 1.00 71.05  ? 20  LYS B CD    1 
ATOM   7438 C CE    . LYS B 2 20  ? 130.321 104.346 115.240 1.00 80.30  ? 20  LYS B CE    1 
ATOM   7439 N NZ    . LYS B 2 20  ? 129.403 104.381 116.411 1.00 89.40  ? 20  LYS B NZ    1 
ATOM   7440 N N     . TYR B 2 21  ? 133.996 109.872 113.773 1.00 49.21  ? 21  TYR B N     1 
ATOM   7441 C CA    . TYR B 2 21  ? 134.654 110.961 113.067 1.00 42.84  ? 21  TYR B CA    1 
ATOM   7442 C C     . TYR B 2 21  ? 135.951 111.413 113.725 1.00 48.07  ? 21  TYR B C     1 
ATOM   7443 O O     . TYR B 2 21  ? 136.581 112.351 113.230 1.00 50.62  ? 21  TYR B O     1 
ATOM   7444 C CB    . TYR B 2 21  ? 133.703 112.152 112.930 1.00 43.19  ? 21  TYR B CB    1 
ATOM   7445 C CG    . TYR B 2 21  ? 133.120 112.639 114.232 1.00 43.23  ? 21  TYR B CG    1 
ATOM   7446 C CD1   . TYR B 2 21  ? 133.798 113.555 115.018 1.00 45.50  ? 21  TYR B CD1   1 
ATOM   7447 C CD2   . TYR B 2 21  ? 131.882 112.196 114.664 1.00 50.91  ? 21  TYR B CD2   1 
ATOM   7448 C CE1   . TYR B 2 21  ? 133.264 114.008 116.203 1.00 50.78  ? 21  TYR B CE1   1 
ATOM   7449 C CE2   . TYR B 2 21  ? 131.339 112.643 115.845 1.00 51.97  ? 21  TYR B CE2   1 
ATOM   7450 C CZ    . TYR B 2 21  ? 132.034 113.548 116.611 1.00 52.42  ? 21  TYR B CZ    1 
ATOM   7451 O OH    . TYR B 2 21  ? 131.495 113.993 117.792 1.00 59.31  ? 21  TYR B OH    1 
ATOM   7452 N N     . LEU B 2 22  ? 136.363 110.783 114.820 1.00 52.21  ? 22  LEU B N     1 
ATOM   7453 C CA    . LEU B 2 22  ? 137.632 111.080 115.466 1.00 42.96  ? 22  LEU B CA    1 
ATOM   7454 C C     . LEU B 2 22  ? 138.537 109.861 115.397 1.00 42.15  ? 22  LEU B C     1 
ATOM   7455 O O     . LEU B 2 22  ? 138.065 108.721 115.390 1.00 51.96  ? 22  LEU B O     1 
ATOM   7456 C CB    . LEU B 2 22  ? 137.432 111.490 116.924 1.00 36.16  ? 22  LEU B CB    1 
ATOM   7457 C CG    . LEU B 2 22  ? 136.592 112.737 117.177 1.00 36.63  ? 22  LEU B CG    1 
ATOM   7458 C CD1   . LEU B 2 22  ? 136.125 112.749 118.613 1.00 34.90  ? 22  LEU B CD1   1 
ATOM   7459 C CD2   . LEU B 2 22  ? 137.393 113.986 116.869 1.00 43.04  ? 22  LEU B CD2   1 
ATOM   7460 N N     . ARG B 2 23  ? 139.844 110.109 115.347 1.00 38.84  ? 23  ARG B N     1 
ATOM   7461 C CA    . ARG B 2 23  ? 140.828 109.039 115.340 1.00 44.23  ? 23  ARG B CA    1 
ATOM   7462 C C     . ARG B 2 23  ? 142.100 109.532 116.015 1.00 41.15  ? 23  ARG B C     1 
ATOM   7463 O O     . ARG B 2 23  ? 142.397 110.729 116.007 1.00 43.50  ? 23  ARG B O     1 
ATOM   7464 C CB    . ARG B 2 23  ? 141.131 108.564 113.912 1.00 47.81  ? 23  ARG B CB    1 
ATOM   7465 C CG    . ARG B 2 23  ? 141.049 107.054 113.706 1.00 61.07  ? 23  ARG B CG    1 
ATOM   7466 C CD    . ARG B 2 23  ? 139.614 106.555 113.812 1.00 67.39  ? 23  ARG B CD    1 
ATOM   7467 N NE    . ARG B 2 23  ? 139.469 105.161 113.409 1.00 75.01  ? 23  ARG B NE    1 
ATOM   7468 C CZ    . ARG B 2 23  ? 138.325 104.490 113.434 1.00 73.39  ? 23  ARG B CZ    1 
ATOM   7469 N NH1   . ARG B 2 23  ? 137.200 105.053 113.847 1.00 76.26  ? 23  ARG B NH1   1 
ATOM   7470 N NH2   . ARG B 2 23  ? 138.308 103.221 113.035 1.00 63.14  ? 23  ARG B NH2   1 
ATOM   7471 N N     . ASN B 2 24  ? 142.841 108.596 116.609 1.00 35.71  ? 24  ASN B N     1 
ATOM   7472 C CA    . ASN B 2 24  ? 144.171 108.856 117.167 1.00 37.15  ? 24  ASN B CA    1 
ATOM   7473 C C     . ASN B 2 24  ? 144.146 109.939 118.249 1.00 36.67  ? 24  ASN B C     1 
ATOM   7474 O O     . ASN B 2 24  ? 144.932 110.888 118.229 1.00 39.73  ? 24  ASN B O     1 
ATOM   7475 C CB    . ASN B 2 24  ? 145.163 109.215 116.059 1.00 38.44  ? 24  ASN B CB    1 
ATOM   7476 C CG    . ASN B 2 24  ? 146.603 109.054 116.495 1.00 47.39  ? 24  ASN B CG    1 
ATOM   7477 O OD1   . ASN B 2 24  ? 146.903 108.288 117.411 1.00 48.11  ? 24  ASN B OD1   1 
ATOM   7478 N ND2   . ASN B 2 24  ? 147.506 109.775 115.840 1.00 51.92  ? 24  ASN B ND2   1 
ATOM   7479 N N     . LEU B 2 25  ? 143.232 109.792 119.203 1.00 36.02  ? 25  LEU B N     1 
ATOM   7480 C CA    . LEU B 2 25  ? 143.183 110.701 120.343 1.00 31.56  ? 25  LEU B CA    1 
ATOM   7481 C C     . LEU B 2 25  ? 144.247 110.315 121.364 1.00 34.10  ? 25  LEU B C     1 
ATOM   7482 O O     . LEU B 2 25  ? 144.260 109.183 121.857 1.00 42.49  ? 25  LEU B O     1 
ATOM   7483 C CB    . LEU B 2 25  ? 141.797 110.677 120.978 1.00 30.38  ? 25  LEU B CB    1 
ATOM   7484 C CG    . LEU B 2 25  ? 141.563 111.603 122.168 1.00 28.59  ? 25  LEU B CG    1 
ATOM   7485 C CD1   . LEU B 2 25  ? 141.801 113.047 121.782 1.00 31.82  ? 25  LEU B CD1   1 
ATOM   7486 C CD2   . LEU B 2 25  ? 140.153 111.421 122.694 1.00 32.14  ? 25  LEU B CD2   1 
ATOM   7487 N N     . SER B 2 26  ? 145.143 111.249 121.679 1.00 30.75  ? 26  SER B N     1 
ATOM   7488 C CA    . SER B 2 26  ? 146.192 110.988 122.654 1.00 31.08  ? 26  SER B CA    1 
ATOM   7489 C C     . SER B 2 26  ? 146.667 112.299 123.262 1.00 36.47  ? 26  SER B C     1 
ATOM   7490 O O     . SER B 2 26  ? 146.658 113.342 122.606 1.00 44.46  ? 26  SER B O     1 
ATOM   7491 C CB    . SER B 2 26  ? 147.375 110.250 122.020 1.00 33.29  ? 26  SER B CB    1 
ATOM   7492 O OG    . SER B 2 26  ? 148.412 110.056 122.964 1.00 40.29  ? 26  SER B OG    1 
ATOM   7493 N N     . SER B 2 27  ? 147.085 112.232 124.525 1.00 36.79  ? 27  SER B N     1 
ATOM   7494 C CA    . SER B 2 27  ? 147.713 113.358 125.195 1.00 40.37  ? 27  SER B CA    1 
ATOM   7495 C C     . SER B 2 27  ? 149.232 113.229 125.105 1.00 52.85  ? 27  SER B C     1 
ATOM   7496 O O     . SER B 2 27  ? 149.767 112.332 124.450 1.00 59.82  ? 27  SER B O     1 
ATOM   7497 C CB    . SER B 2 27  ? 147.246 113.447 126.645 1.00 42.92  ? 27  SER B CB    1 
ATOM   7498 O OG    . SER B 2 27  ? 145.884 113.828 126.719 1.00 43.43  ? 27  SER B OG    1 
ATOM   7499 N N     . GLU B 2 28  ? 149.944 114.136 125.767 1.00 53.01  ? 28  GLU B N     1 
ATOM   7500 C CA    . GLU B 2 28  ? 151.402 114.080 125.777 1.00 61.56  ? 28  GLU B CA    1 
ATOM   7501 C C     . GLU B 2 28  ? 151.958 113.188 126.884 1.00 67.36  ? 28  GLU B C     1 
ATOM   7502 O O     . GLU B 2 28  ? 153.172 113.198 127.115 1.00 67.29  ? 28  GLU B O     1 
ATOM   7503 C CB    . GLU B 2 28  ? 151.977 115.492 125.892 1.00 65.50  ? 28  GLU B CB    1 
ATOM   7504 C CG    . GLU B 2 28  ? 153.067 115.775 124.882 1.00 76.99  ? 28  GLU B CG    1 
ATOM   7505 C CD    . GLU B 2 28  ? 153.444 117.238 124.823 1.00 85.43  ? 28  GLU B CD    1 
ATOM   7506 O OE1   . GLU B 2 28  ? 152.916 118.027 125.635 1.00 78.05  ? 28  GLU B OE1   1 
ATOM   7507 O OE2   . GLU B 2 28  ? 154.272 117.597 123.959 1.00 98.22  ? 28  GLU B OE2   1 
ATOM   7508 N N     . GLU B 2 29  ? 151.085 112.470 127.595 1.00 71.60  ? 29  GLU B N     1 
ATOM   7509 C CA    . GLU B 2 29  ? 151.419 111.407 128.543 1.00 76.83  ? 29  GLU B CA    1 
ATOM   7510 C C     . GLU B 2 29  ? 152.075 111.951 129.809 1.00 77.31  ? 29  GLU B C     1 
ATOM   7511 O O     . GLU B 2 29  ? 152.235 111.223 130.794 1.00 83.61  ? 29  GLU B O     1 
ATOM   7512 C CB    . GLU B 2 29  ? 152.315 110.348 127.883 1.00 78.41  ? 29  GLU B CB    1 
ATOM   7513 C CG    . GLU B 2 29  ? 152.565 109.091 128.727 1.00 83.89  ? 29  GLU B CG    1 
ATOM   7514 C CD    . GLU B 2 29  ? 151.367 108.155 128.799 1.00 88.87  ? 29  GLU B CD    1 
ATOM   7515 O OE1   . GLU B 2 29  ? 150.276 108.524 128.316 1.00 80.37  ? 29  GLU B OE1   1 
ATOM   7516 O OE2   . GLU B 2 29  ? 151.524 107.037 129.336 1.00 92.83  ? 29  GLU B OE2   1 
ATOM   7517 N N     . ASP B 2 30  ? 152.446 113.228 129.808 1.00 64.55  ? 30  ASP B N     1 
ATOM   7518 C CA    . ASP B 2 30  ? 152.702 113.955 131.042 1.00 62.24  ? 30  ASP B CA    1 
ATOM   7519 C C     . ASP B 2 30  ? 151.865 115.225 131.151 1.00 58.52  ? 30  ASP B C     1 
ATOM   7520 O O     . ASP B 2 30  ? 152.053 115.998 132.095 1.00 65.54  ? 30  ASP B O     1 
ATOM   7521 C CB    . ASP B 2 30  ? 154.202 114.263 131.201 1.00 65.24  ? 30  ASP B CB    1 
ATOM   7522 C CG    . ASP B 2 30  ? 154.805 114.996 130.010 1.00 77.83  ? 30  ASP B CG    1 
ATOM   7523 O OD1   . ASP B 2 30  ? 154.075 115.363 129.068 1.00 78.59  ? 30  ASP B OD1   1 
ATOM   7524 O OD2   . ASP B 2 30  ? 156.038 115.203 130.032 1.00 84.16  ? 30  ASP B OD2   1 
ATOM   7525 N N     . ASN B 2 31  ? 150.922 115.439 130.230 1.00 47.99  ? 31  ASN B N     1 
ATOM   7526 C CA    . ASN B 2 31  ? 150.059 116.619 130.276 1.00 40.70  ? 31  ASN B CA    1 
ATOM   7527 C C     . ASN B 2 31  ? 148.714 116.235 129.668 1.00 40.55  ? 31  ASN B C     1 
ATOM   7528 O O     . ASN B 2 31  ? 148.539 116.309 128.449 1.00 45.20  ? 31  ASN B O     1 
ATOM   7529 C CB    . ASN B 2 31  ? 150.689 117.794 129.540 1.00 47.70  ? 31  ASN B CB    1 
ATOM   7530 C CG    . ASN B 2 31  ? 149.853 119.060 129.631 1.00 48.68  ? 31  ASN B CG    1 
ATOM   7531 O OD1   . ASN B 2 31  ? 148.937 119.156 130.444 1.00 48.97  ? 31  ASN B OD1   1 
ATOM   7532 N ND2   . ASN B 2 31  ? 150.173 120.042 128.799 1.00 51.62  ? 31  ASN B ND2   1 
ATOM   7533 N N     . VAL B 2 32  ? 147.768 115.846 130.524 1.00 42.70  ? 32  VAL B N     1 
ATOM   7534 C CA    . VAL B 2 32  ? 146.449 115.458 130.040 1.00 42.73  ? 32  VAL B CA    1 
ATOM   7535 C C     . VAL B 2 32  ? 145.617 116.662 129.626 1.00 42.22  ? 32  VAL B C     1 
ATOM   7536 O O     . VAL B 2 32  ? 144.579 116.492 128.975 1.00 47.40  ? 32  VAL B O     1 
ATOM   7537 C CB    . VAL B 2 32  ? 145.695 114.623 131.090 1.00 42.09  ? 32  VAL B CB    1 
ATOM   7538 C CG1   . VAL B 2 32  ? 146.502 113.389 131.464 1.00 39.27  ? 32  VAL B CG1   1 
ATOM   7539 C CG2   . VAL B 2 32  ? 145.366 115.456 132.322 1.00 45.54  ? 32  VAL B CG2   1 
ATOM   7540 N N     . LEU B 2 33  ? 146.047 117.873 129.966 1.00 38.54  ? 33  LEU B N     1 
ATOM   7541 C CA    . LEU B 2 33  ? 145.310 119.076 129.605 1.00 39.87  ? 33  LEU B CA    1 
ATOM   7542 C C     . LEU B 2 33  ? 145.437 119.440 128.131 1.00 38.37  ? 33  LEU B C     1 
ATOM   7543 O O     . LEU B 2 33  ? 144.792 120.396 127.695 1.00 38.80  ? 33  LEU B O     1 
ATOM   7544 C CB    . LEU B 2 33  ? 145.774 120.251 130.467 1.00 43.46  ? 33  LEU B CB    1 
ATOM   7545 C CG    . LEU B 2 33  ? 145.537 120.118 131.970 1.00 43.65  ? 33  LEU B CG    1 
ATOM   7546 C CD1   . LEU B 2 33  ? 146.114 121.321 132.697 1.00 44.70  ? 33  LEU B CD1   1 
ATOM   7547 C CD2   . LEU B 2 33  ? 144.054 119.968 132.261 1.00 45.95  ? 33  LEU B CD2   1 
ATOM   7548 N N     . VAL B 2 34  ? 146.253 118.726 127.358 1.00 38.29  ? 34  VAL B N     1 
ATOM   7549 C CA    . VAL B 2 34  ? 146.349 118.936 125.918 1.00 32.76  ? 34  VAL B CA    1 
ATOM   7550 C C     . VAL B 2 34  ? 146.066 117.613 125.219 1.00 39.60  ? 34  VAL B C     1 
ATOM   7551 O O     . VAL B 2 34  ? 146.641 116.578 125.574 1.00 44.60  ? 34  VAL B O     1 
ATOM   7552 C CB    . VAL B 2 34  ? 147.720 119.502 125.496 1.00 29.80  ? 34  VAL B CB    1 
ATOM   7553 C CG1   . VAL B 2 34  ? 148.854 118.635 126.006 1.00 35.04  ? 34  VAL B CG1   1 
ATOM   7554 C CG2   . VAL B 2 34  ? 147.792 119.657 123.984 1.00 34.96  ? 34  VAL B CG2   1 
ATOM   7555 N N     . TRP B 2 35  ? 145.160 117.644 124.247 1.00 37.41  ? 35  TRP B N     1 
ATOM   7556 C CA    . TRP B 2 35  ? 144.777 116.477 123.468 1.00 31.54  ? 35  TRP B CA    1 
ATOM   7557 C C     . TRP B 2 35  ? 145.149 116.695 122.010 1.00 33.28  ? 35  TRP B C     1 
ATOM   7558 O O     . TRP B 2 35  ? 145.012 117.804 121.488 1.00 37.75  ? 35  TRP B O     1 
ATOM   7559 C CB    . TRP B 2 35  ? 143.276 116.206 123.551 1.00 31.38  ? 35  TRP B CB    1 
ATOM   7560 C CG    . TRP B 2 35  ? 142.749 115.882 124.901 1.00 30.32  ? 35  TRP B CG    1 
ATOM   7561 C CD1   . TRP B 2 35  ? 143.442 115.833 126.068 1.00 33.03  ? 35  TRP B CD1   1 
ATOM   7562 C CD2   . TRP B 2 35  ? 141.393 115.566 125.223 1.00 37.61  ? 35  TRP B CD2   1 
ATOM   7563 N NE1   . TRP B 2 35  ? 142.601 115.506 127.104 1.00 37.64  ? 35  TRP B NE1   1 
ATOM   7564 C CE2   . TRP B 2 35  ? 141.336 115.334 126.607 1.00 41.57  ? 35  TRP B CE2   1 
ATOM   7565 C CE3   . TRP B 2 35  ? 140.219 115.459 124.471 1.00 37.96  ? 35  TRP B CE3   1 
ATOM   7566 C CZ2   . TRP B 2 35  ? 140.152 115.002 127.258 1.00 44.67  ? 35  TRP B CZ2   1 
ATOM   7567 C CZ3   . TRP B 2 35  ? 139.048 115.128 125.116 1.00 38.19  ? 35  TRP B CZ3   1 
ATOM   7568 C CH2   . TRP B 2 35  ? 139.020 114.902 126.495 1.00 46.43  ? 35  TRP B CH2   1 
ATOM   7569 N N     . HIS B 2 36  ? 145.594 115.629 121.356 1.00 29.21  ? 36  HIS B N     1 
ATOM   7570 C CA    . HIS B 2 36  ? 145.837 115.617 119.922 1.00 28.60  ? 36  HIS B CA    1 
ATOM   7571 C C     . HIS B 2 36  ? 144.932 114.579 119.277 1.00 34.56  ? 36  HIS B C     1 
ATOM   7572 O O     . HIS B 2 36  ? 144.758 113.478 119.807 1.00 44.05  ? 36  HIS B O     1 
ATOM   7573 C CB    . HIS B 2 36  ? 147.301 115.310 119.604 1.00 28.04  ? 36  HIS B CB    1 
ATOM   7574 C CG    . HIS B 2 36  ? 148.268 116.268 120.224 1.00 36.12  ? 36  HIS B CG    1 
ATOM   7575 N ND1   . HIS B 2 36  ? 148.439 117.555 119.764 1.00 43.26  ? 36  HIS B ND1   1 
ATOM   7576 C CD2   . HIS B 2 36  ? 149.123 116.124 121.264 1.00 38.34  ? 36  HIS B CD2   1 
ATOM   7577 C CE1   . HIS B 2 36  ? 149.354 118.165 120.496 1.00 41.38  ? 36  HIS B CE1   1 
ATOM   7578 N NE2   . HIS B 2 36  ? 149.785 117.318 121.413 1.00 41.03  ? 36  HIS B NE2   1 
ATOM   7579 N N     . ALA B 2 37  ? 144.354 114.934 118.134 1.00 30.59  ? 37  ALA B N     1 
ATOM   7580 C CA    . ALA B 2 37  ? 143.398 114.067 117.465 1.00 31.04  ? 37  ALA B CA    1 
ATOM   7581 C C     . ALA B 2 37  ? 143.517 114.259 115.961 1.00 36.96  ? 37  ALA B C     1 
ATOM   7582 O O     . ALA B 2 37  ? 144.165 115.191 115.481 1.00 44.68  ? 37  ALA B O     1 
ATOM   7583 C CB    . ALA B 2 37  ? 141.971 114.345 117.940 1.00 36.06  ? 37  ALA B CB    1 
ATOM   7584 N N     . LEU B 2 38  ? 142.896 113.350 115.218 1.00 36.42  ? 38  LEU B N     1 
ATOM   7585 C CA    . LEU B 2 38  ? 142.820 113.417 113.760 1.00 33.11  ? 38  LEU B CA    1 
ATOM   7586 C C     . LEU B 2 38  ? 141.346 113.420 113.372 1.00 37.21  ? 38  LEU B C     1 
ATOM   7587 O O     . LEU B 2 38  ? 140.725 112.358 113.265 1.00 45.98  ? 38  LEU B O     1 
ATOM   7588 C CB    . LEU B 2 38  ? 143.558 112.250 113.110 1.00 38.89  ? 38  LEU B CB    1 
ATOM   7589 C CG    . LEU B 2 38  ? 145.044 112.398 112.774 1.00 42.62  ? 38  LEU B CG    1 
ATOM   7590 C CD1   . LEU B 2 38  ? 145.878 112.660 114.015 1.00 40.73  ? 38  LEU B CD1   1 
ATOM   7591 C CD2   . LEU B 2 38  ? 145.540 111.158 112.052 1.00 50.12  ? 38  LEU B CD2   1 
ATOM   7592 N N     . LEU B 2 39  ? 140.787 114.606 113.162 1.00 38.18  ? 39  LEU B N     1 
ATOM   7593 C CA    . LEU B 2 39  ? 139.394 114.707 112.753 1.00 40.39  ? 39  LEU B CA    1 
ATOM   7594 C C     . LEU B 2 39  ? 139.220 114.193 111.330 1.00 43.27  ? 39  LEU B C     1 
ATOM   7595 O O     . LEU B 2 39  ? 140.037 114.472 110.443 1.00 50.11  ? 39  LEU B O     1 
ATOM   7596 C CB    . LEU B 2 39  ? 138.907 116.152 112.856 1.00 43.80  ? 39  LEU B CB    1 
ATOM   7597 C CG    . LEU B 2 39  ? 137.414 116.387 112.622 1.00 34.58  ? 39  LEU B CG    1 
ATOM   7598 C CD1   . LEU B 2 39  ? 136.584 115.592 113.606 1.00 41.59  ? 39  LEU B CD1   1 
ATOM   7599 C CD2   . LEU B 2 39  ? 137.082 117.858 112.726 1.00 41.97  ? 39  LEU B CD2   1 
ATOM   7600 N N     . LEU B 2 40  ? 138.139 113.438 111.120 1.00 40.86  ? 40  LEU B N     1 
ATOM   7601 C CA    . LEU B 2 40  ? 137.819 112.808 109.843 1.00 42.59  ? 40  LEU B CA    1 
ATOM   7602 C C     . LEU B 2 40  ? 136.569 113.457 109.261 1.00 48.01  ? 40  LEU B C     1 
ATOM   7603 O O     . LEU B 2 40  ? 135.443 113.069 109.603 1.00 46.72  ? 40  LEU B O     1 
ATOM   7604 C CB    . LEU B 2 40  ? 137.615 111.302 110.022 1.00 39.79  ? 40  LEU B CB    1 
ATOM   7605 C CG    . LEU B 2 40  ? 138.820 110.492 110.508 1.00 50.54  ? 40  LEU B CG    1 
ATOM   7606 C CD1   . LEU B 2 40  ? 138.398 109.070 110.844 1.00 52.82  ? 40  LEU B CD1   1 
ATOM   7607 C CD2   . LEU B 2 40  ? 139.935 110.485 109.474 1.00 52.51  ? 40  LEU B CD2   1 
ATOM   7608 N N     . PRO B 2 41  ? 136.713 114.446 108.379 1.00 47.30  ? 41  PRO B N     1 
ATOM   7609 C CA    . PRO B 2 41  ? 135.542 115.143 107.835 1.00 36.93  ? 41  PRO B CA    1 
ATOM   7610 C C     . PRO B 2 41  ? 134.707 114.238 106.940 1.00 45.29  ? 41  PRO B C     1 
ATOM   7611 O O     . PRO B 2 41  ? 135.183 113.233 106.408 1.00 49.33  ? 41  PRO B O     1 
ATOM   7612 C CB    . PRO B 2 41  ? 136.156 116.298 107.033 1.00 42.98  ? 41  PRO B CB    1 
ATOM   7613 C CG    . PRO B 2 41  ? 137.596 116.368 107.458 1.00 44.18  ? 41  PRO B CG    1 
ATOM   7614 C CD    . PRO B 2 41  ? 137.975 114.987 107.849 1.00 50.02  ? 41  PRO B CD    1 
ATOM   7615 N N     . GLU B 2 42  ? 133.434 114.614 106.778 1.00 49.10  ? 42  GLU B N     1 
ATOM   7616 C CA    . GLU B 2 42  ? 132.504 113.876 105.934 1.00 53.81  ? 42  GLU B CA    1 
ATOM   7617 C C     . GLU B 2 42  ? 131.893 114.698 104.807 1.00 54.84  ? 42  GLU B C     1 
ATOM   7618 O O     . GLU B 2 42  ? 131.246 114.117 103.927 1.00 62.09  ? 42  GLU B O     1 
ATOM   7619 C CB    . GLU B 2 42  ? 131.369 113.275 106.779 1.00 60.39  ? 42  GLU B CB    1 
ATOM   7620 C CG    . GLU B 2 42  ? 131.798 112.105 107.652 1.00 64.67  ? 42  GLU B CG    1 
ATOM   7621 C CD    . GLU B 2 42  ? 130.637 111.477 108.397 1.00 75.56  ? 42  GLU B CD    1 
ATOM   7622 O OE1   . GLU B 2 42  ? 129.540 112.074 108.396 1.00 76.93  ? 42  GLU B OE1   1 
ATOM   7623 O OE2   . GLU B 2 42  ? 130.819 110.387 108.982 1.00 79.98  ? 42  GLU B OE2   1 
ATOM   7624 N N     . ARG B 2 43  ? 132.064 116.014 104.807 1.00 51.94  ? 43  ARG B N     1 
ATOM   7625 C CA    . ARG B 2 43  ? 131.582 116.828 103.702 1.00 53.23  ? 43  ARG B CA    1 
ATOM   7626 C C     . ARG B 2 43  ? 132.346 116.462 102.430 1.00 55.39  ? 43  ARG B C     1 
ATOM   7627 O O     . ARG B 2 43  ? 133.531 116.120 102.500 1.00 57.23  ? 43  ARG B O     1 
ATOM   7628 C CB    . ARG B 2 43  ? 131.758 118.312 104.025 1.00 55.16  ? 43  ARG B CB    1 
ATOM   7629 C CG    . ARG B 2 43  ? 130.697 119.219 103.429 1.00 60.73  ? 43  ARG B CG    1 
ATOM   7630 C CD    . ARG B 2 43  ? 130.714 120.592 104.071 1.00 61.65  ? 43  ARG B CD    1 
ATOM   7631 N NE    . ARG B 2 43  ? 129.603 121.413 103.608 1.00 60.79  ? 43  ARG B NE    1 
ATOM   7632 C CZ    . ARG B 2 43  ? 129.691 122.315 102.641 1.00 57.46  ? 43  ARG B CZ    1 
ATOM   7633 N NH1   . ARG B 2 43  ? 130.837 122.563 102.029 1.00 58.53  ? 43  ARG B NH1   1 
ATOM   7634 N NH2   . ARG B 2 43  ? 128.602 122.984 102.277 1.00 51.96  ? 43  ARG B NH2   1 
ATOM   7635 N N     . PRO B 2 44  ? 131.705 116.505 101.262 1.00 56.90  ? 44  PRO B N     1 
ATOM   7636 C CA    . PRO B 2 44  ? 132.370 116.069 100.019 1.00 57.52  ? 44  PRO B CA    1 
ATOM   7637 C C     . PRO B 2 44  ? 133.702 116.761 99.773  1.00 55.64  ? 44  PRO B C     1 
ATOM   7638 O O     . PRO B 2 44  ? 134.652 116.102 99.325  1.00 55.24  ? 44  PRO B O     1 
ATOM   7639 C CB    . PRO B 2 44  ? 131.341 116.418 98.933  1.00 60.20  ? 44  PRO B CB    1 
ATOM   7640 C CG    . PRO B 2 44  ? 130.037 116.291 99.628  1.00 62.11  ? 44  PRO B CG    1 
ATOM   7641 C CD    . PRO B 2 44  ? 130.265 116.742 101.052 1.00 60.19  ? 44  PRO B CD    1 
ATOM   7642 N N     . PRO B 2 45  ? 133.844 118.070 100.033 1.00 51.57  ? 45  PRO B N     1 
ATOM   7643 C CA    . PRO B 2 45  ? 135.164 118.675 99.781  1.00 47.49  ? 45  PRO B CA    1 
ATOM   7644 C C     . PRO B 2 45  ? 136.219 118.284 100.800 1.00 52.64  ? 45  PRO B C     1 
ATOM   7645 O O     . PRO B 2 45  ? 137.373 118.045 100.425 1.00 54.31  ? 45  PRO B O     1 
ATOM   7646 C CB    . PRO B 2 45  ? 134.869 120.179 99.816  1.00 51.61  ? 45  PRO B CB    1 
ATOM   7647 C CG    . PRO B 2 45  ? 133.708 120.299 100.713 1.00 52.55  ? 45  PRO B CG    1 
ATOM   7648 C CD    . PRO B 2 45  ? 132.854 119.113 100.374 1.00 54.70  ? 45  PRO B CD    1 
ATOM   7649 N N     . TYR B 2 46  ? 135.857 118.207 102.081 1.00 55.02  ? 46  TYR B N     1 
ATOM   7650 C CA    . TYR B 2 46  ? 136.837 118.021 103.142 1.00 46.44  ? 46  TYR B CA    1 
ATOM   7651 C C     . TYR B 2 46  ? 137.171 116.563 103.429 1.00 47.17  ? 46  TYR B C     1 
ATOM   7652 O O     . TYR B 2 46  ? 138.191 116.300 104.076 1.00 53.64  ? 46  TYR B O     1 
ATOM   7653 C CB    . TYR B 2 46  ? 136.349 118.677 104.436 1.00 42.57  ? 46  TYR B CB    1 
ATOM   7654 C CG    . TYR B 2 46  ? 136.125 120.162 104.322 1.00 44.42  ? 46  TYR B CG    1 
ATOM   7655 C CD1   . TYR B 2 46  ? 137.195 121.042 104.250 1.00 47.03  ? 46  TYR B CD1   1 
ATOM   7656 C CD2   . TYR B 2 46  ? 134.846 120.687 104.303 1.00 46.73  ? 46  TYR B CD2   1 
ATOM   7657 C CE1   . TYR B 2 46  ? 136.992 122.402 104.144 1.00 41.68  ? 46  TYR B CE1   1 
ATOM   7658 C CE2   . TYR B 2 46  ? 134.635 122.043 104.200 1.00 50.65  ? 46  TYR B CE2   1 
ATOM   7659 C CZ    . TYR B 2 46  ? 135.712 122.895 104.120 1.00 45.71  ? 46  TYR B CZ    1 
ATOM   7660 O OH    . TYR B 2 46  ? 135.507 124.249 104.009 1.00 48.84  ? 46  TYR B OH    1 
ATOM   7661 N N     . ASN B 2 47  ? 136.352 115.613 102.973 1.00 46.08  ? 47  ASN B N     1 
ATOM   7662 C CA    . ASN B 2 47  ? 136.543 114.220 103.363 1.00 48.91  ? 47  ASN B CA    1 
ATOM   7663 C C     . ASN B 2 47  ? 137.764 113.573 102.721 1.00 49.83  ? 47  ASN B C     1 
ATOM   7664 O O     . ASN B 2 47  ? 138.124 112.457 103.110 1.00 58.11  ? 47  ASN B O     1 
ATOM   7665 C CB    . ASN B 2 47  ? 135.289 113.399 103.039 1.00 48.20  ? 47  ASN B CB    1 
ATOM   7666 C CG    . ASN B 2 47  ? 134.914 113.445 101.570 1.00 53.33  ? 47  ASN B CG    1 
ATOM   7667 O OD1   . ASN B 2 47  ? 135.742 113.730 100.707 1.00 54.88  ? 47  ASN B OD1   1 
ATOM   7668 N ND2   . ASN B 2 47  ? 133.650 113.157 101.279 1.00 61.73  ? 47  ASN B ND2   1 
ATOM   7669 N N     . LEU B 2 48  ? 138.403 114.234 101.755 1.00 48.05  ? 48  LEU B N     1 
ATOM   7670 C CA    . LEU B 2 48  ? 139.543 113.634 101.074 1.00 53.19  ? 48  LEU B CA    1 
ATOM   7671 C C     . LEU B 2 48  ? 140.766 113.518 101.972 1.00 49.05  ? 48  LEU B C     1 
ATOM   7672 O O     . LEU B 2 48  ? 141.674 112.742 101.659 1.00 52.45  ? 48  LEU B O     1 
ATOM   7673 C CB    . LEU B 2 48  ? 139.896 114.445 99.825  1.00 61.48  ? 48  LEU B CB    1 
ATOM   7674 C CG    . LEU B 2 48  ? 138.789 114.629 98.784  1.00 54.23  ? 48  LEU B CG    1 
ATOM   7675 C CD1   . LEU B 2 48  ? 139.286 115.476 97.626  1.00 49.55  ? 48  LEU B CD1   1 
ATOM   7676 C CD2   . LEU B 2 48  ? 138.286 113.286 98.289  1.00 48.84  ? 48  LEU B CD2   1 
ATOM   7677 N N     . LYS B 2 49  ? 140.817 114.267 103.070 1.00 50.54  ? 49  LYS B N     1 
ATOM   7678 C CA    . LYS B 2 49  ? 141.972 114.267 103.954 1.00 57.94  ? 49  LYS B CA    1 
ATOM   7679 C C     . LYS B 2 49  ? 141.512 114.349 105.402 1.00 61.34  ? 49  LYS B C     1 
ATOM   7680 O O     . LYS B 2 49  ? 140.373 114.721 105.694 1.00 57.20  ? 49  LYS B O     1 
ATOM   7681 C CB    . LYS B 2 49  ? 142.922 115.429 103.636 1.00 55.93  ? 49  LYS B CB    1 
ATOM   7682 C CG    . LYS B 2 49  ? 143.683 115.284 102.330 1.00 58.86  ? 49  LYS B CG    1 
ATOM   7683 C CD    . LYS B 2 49  ? 144.759 114.220 102.433 1.00 66.05  ? 49  LYS B CD    1 
ATOM   7684 C CE    . LYS B 2 49  ? 145.617 114.181 101.179 1.00 67.66  ? 49  LYS B CE    1 
ATOM   7685 N NZ    . LYS B 2 49  ? 146.770 113.251 101.323 1.00 68.08  ? 49  LYS B NZ    1 
ATOM   7686 N N     . ALA B 2 50  ? 142.417 113.995 106.310 1.00 68.39  ? 50  ALA B N     1 
ATOM   7687 C CA    . ALA B 2 50  ? 142.193 114.085 107.745 1.00 64.40  ? 50  ALA B CA    1 
ATOM   7688 C C     . ALA B 2 50  ? 142.966 115.269 108.311 1.00 61.40  ? 50  ALA B C     1 
ATOM   7689 O O     . ALA B 2 50  ? 144.026 115.638 107.797 1.00 59.77  ? 50  ALA B O     1 
ATOM   7690 C CB    . ALA B 2 50  ? 142.618 112.797 108.455 1.00 60.91  ? 50  ALA B CB    1 
ATOM   7691 N N     . PHE B 2 51  ? 142.435 115.866 109.376 1.00 54.19  ? 51  PHE B N     1 
ATOM   7692 C CA    . PHE B 2 51  ? 142.965 117.120 109.900 1.00 48.73  ? 51  PHE B CA    1 
ATOM   7693 C C     . PHE B 2 51  ? 143.463 116.936 111.325 1.00 48.13  ? 51  PHE B C     1 
ATOM   7694 O O     . PHE B 2 51  ? 142.700 116.525 112.203 1.00 48.48  ? 51  PHE B O     1 
ATOM   7695 C CB    . PHE B 2 51  ? 141.899 118.215 109.844 1.00 58.64  ? 51  PHE B CB    1 
ATOM   7696 C CG    . PHE B 2 51  ? 141.474 118.569 108.450 1.00 66.35  ? 51  PHE B CG    1 
ATOM   7697 C CD1   . PHE B 2 51  ? 142.417 118.753 107.452 1.00 71.77  ? 51  PHE B CD1   1 
ATOM   7698 C CD2   . PHE B 2 51  ? 140.134 118.707 108.132 1.00 59.76  ? 51  PHE B CD2   1 
ATOM   7699 C CE1   . PHE B 2 51  ? 142.033 119.075 106.168 1.00 68.13  ? 51  PHE B CE1   1 
ATOM   7700 C CE2   . PHE B 2 51  ? 139.745 119.031 106.850 1.00 58.18  ? 51  PHE B CE2   1 
ATOM   7701 C CZ    . PHE B 2 51  ? 140.696 119.213 105.866 1.00 62.84  ? 51  PHE B CZ    1 
ATOM   7702 N N     . ARG B 2 52  ? 144.735 117.257 111.556 1.00 58.35  ? 52  ARG B N     1 
ATOM   7703 C CA    . ARG B 2 52  ? 145.267 117.252 112.911 1.00 45.66  ? 52  ARG B CA    1 
ATOM   7704 C C     . ARG B 2 52  ? 144.583 118.324 113.748 1.00 41.26  ? 52  ARG B C     1 
ATOM   7705 O O     . ARG B 2 52  ? 144.251 119.405 113.255 1.00 46.66  ? 52  ARG B O     1 
ATOM   7706 C CB    . ARG B 2 52  ? 146.778 117.478 112.898 1.00 45.20  ? 52  ARG B CB    1 
ATOM   7707 C CG    . ARG B 2 52  ? 147.585 116.276 112.454 1.00 53.26  ? 52  ARG B CG    1 
ATOM   7708 C CD    . ARG B 2 52  ? 149.062 116.619 112.323 1.00 75.87  ? 52  ARG B CD    1 
ATOM   7709 N NE    . ARG B 2 52  ? 149.868 115.440 112.030 1.00 89.27  ? 52  ARG B NE    1 
ATOM   7710 C CZ    . ARG B 2 52  ? 151.158 115.466 111.726 1.00 96.63  ? 52  ARG B CZ    1 
ATOM   7711 N NH1   . ARG B 2 52  ? 151.830 116.604 111.656 1.00 95.38  ? 52  ARG B NH1   1 
ATOM   7712 N NH2   . ARG B 2 52  ? 151.791 114.322 111.481 1.00 101.13 ? 52  ARG B NH2   1 
ATOM   7713 N N     . LEU B 2 53  ? 144.374 118.016 115.023 1.00 35.96  ? 53  LEU B N     1 
ATOM   7714 C CA    . LEU B 2 53  ? 143.601 118.867 115.911 1.00 34.90  ? 53  LEU B CA    1 
ATOM   7715 C C     . LEU B 2 53  ? 144.215 118.835 117.300 1.00 42.50  ? 53  LEU B C     1 
ATOM   7716 O O     . LEU B 2 53  ? 144.684 117.787 117.752 1.00 46.75  ? 53  LEU B O     1 
ATOM   7717 C CB    . LEU B 2 53  ? 142.146 118.405 115.970 1.00 34.91  ? 53  LEU B CB    1 
ATOM   7718 C CG    . LEU B 2 53  ? 141.180 119.346 116.673 1.00 37.33  ? 53  LEU B CG    1 
ATOM   7719 C CD1   . LEU B 2 53  ? 140.833 120.493 115.746 1.00 39.55  ? 53  LEU B CD1   1 
ATOM   7720 C CD2   . LEU B 2 53  ? 139.936 118.596 117.124 1.00 46.38  ? 53  LEU B CD2   1 
ATOM   7721 N N     . SER B 2 54  ? 144.203 119.982 117.975 1.00 40.05  ? 54  SER B N     1 
ATOM   7722 C CA    . SER B 2 54  ? 144.707 120.109 119.333 1.00 36.66  ? 54  SER B CA    1 
ATOM   7723 C C     . SER B 2 54  ? 143.645 120.771 120.194 1.00 36.05  ? 54  SER B C     1 
ATOM   7724 O O     . SER B 2 54  ? 143.125 121.835 119.842 1.00 34.22  ? 54  SER B O     1 
ATOM   7725 C CB    . SER B 2 54  ? 146.001 120.923 119.374 1.00 33.80  ? 54  SER B CB    1 
ATOM   7726 O OG    . SER B 2 54  ? 146.430 121.122 120.708 1.00 38.51  ? 54  SER B OG    1 
ATOM   7727 N N     . ILE B 2 55  ? 143.328 120.139 121.317 1.00 35.97  ? 55  ILE B N     1 
ATOM   7728 C CA    . ILE B 2 55  ? 142.361 120.654 122.277 1.00 33.31  ? 55  ILE B CA    1 
ATOM   7729 C C     . ILE B 2 55  ? 143.112 120.982 123.557 1.00 32.46  ? 55  ILE B C     1 
ATOM   7730 O O     . ILE B 2 55  ? 143.656 120.086 124.212 1.00 36.76  ? 55  ILE B O     1 
ATOM   7731 C CB    . ILE B 2 55  ? 141.230 119.651 122.538 1.00 34.85  ? 55  ILE B CB    1 
ATOM   7732 C CG1   . ILE B 2 55  ? 140.588 119.211 121.221 1.00 35.34  ? 55  ILE B CG1   1 
ATOM   7733 C CG2   . ILE B 2 55  ? 140.189 120.254 123.465 1.00 39.81  ? 55  ILE B CG2   1 
ATOM   7734 C CD1   . ILE B 2 55  ? 141.105 117.891 120.696 1.00 36.90  ? 55  ILE B CD1   1 
ATOM   7735 N N     . SER B 2 56  ? 143.141 122.259 123.916 1.00 34.85  ? 56  SER B N     1 
ATOM   7736 C CA    . SER B 2 56  ? 143.873 122.734 125.080 1.00 37.52  ? 56  SER B CA    1 
ATOM   7737 C C     . SER B 2 56  ? 142.891 123.089 126.186 1.00 42.85  ? 56  SER B C     1 
ATOM   7738 O O     . SER B 2 56  ? 141.940 123.845 125.963 1.00 42.56  ? 56  SER B O     1 
ATOM   7739 C CB    . SER B 2 56  ? 144.741 123.942 124.727 1.00 39.19  ? 56  SER B CB    1 
ATOM   7740 O OG    . SER B 2 56  ? 145.760 123.580 123.812 1.00 44.55  ? 56  SER B OG    1 
ATOM   7741 N N     . PHE B 2 57  ? 143.124 122.540 127.360 1.00 43.70  ? 57  PHE B N     1 
ATOM   7742 C CA    . PHE B 2 57  ? 142.310 122.739 128.547 1.00 45.79  ? 57  PHE B CA    1 
ATOM   7743 C C     . PHE B 2 57  ? 143.023 123.684 129.496 1.00 51.48  ? 57  PHE B C     1 
ATOM   7744 O O     . PHE B 2 57  ? 144.169 123.413 129.879 1.00 53.45  ? 57  PHE B O     1 
ATOM   7745 C CB    . PHE B 2 57  ? 142.048 121.407 129.240 1.00 42.86  ? 57  PHE B CB    1 
ATOM   7746 C CG    . PHE B 2 57  ? 141.260 120.428 128.412 1.00 39.17  ? 57  PHE B CG    1 
ATOM   7747 C CD1   . PHE B 2 57  ? 141.891 119.554 127.547 1.00 38.77  ? 57  PHE B CD1   1 
ATOM   7748 C CD2   . PHE B 2 57  ? 139.889 120.375 128.516 1.00 39.55  ? 57  PHE B CD2   1 
ATOM   7749 C CE1   . PHE B 2 57  ? 141.161 118.657 126.802 1.00 36.56  ? 57  PHE B CE1   1 
ATOM   7750 C CE2   . PHE B 2 57  ? 139.159 119.482 127.778 1.00 42.75  ? 57  PHE B CE2   1 
ATOM   7751 C CZ    . PHE B 2 57  ? 139.793 118.621 126.922 1.00 39.94  ? 57  PHE B CZ    1 
ATOM   7752 N N     . PRO B 2 58  ? 142.412 124.799 129.883 1.00 51.24  ? 58  PRO B N     1 
ATOM   7753 C CA    . PRO B 2 58  ? 143.090 125.724 130.795 1.00 54.24  ? 58  PRO B CA    1 
ATOM   7754 C C     . PRO B 2 58  ? 143.160 125.157 132.204 1.00 63.24  ? 58  PRO B C     1 
ATOM   7755 O O     . PRO B 2 58  ? 142.517 124.161 132.539 1.00 69.56  ? 58  PRO B O     1 
ATOM   7756 C CB    . PRO B 2 58  ? 142.215 126.980 130.740 1.00 56.62  ? 58  PRO B CB    1 
ATOM   7757 C CG    . PRO B 2 58  ? 140.860 126.467 130.373 1.00 50.77  ? 58  PRO B CG    1 
ATOM   7758 C CD    . PRO B 2 58  ? 141.087 125.293 129.470 1.00 45.82  ? 58  PRO B CD    1 
ATOM   7759 N N     . ARG B 2 59  ? 143.985 125.804 133.032 1.00 64.22  ? 59  ARG B N     1 
ATOM   7760 C CA    . ARG B 2 59  ? 144.061 125.423 134.440 1.00 66.91  ? 59  ARG B CA    1 
ATOM   7761 C C     . ARG B 2 59  ? 142.719 125.606 135.138 1.00 65.30  ? 59  ARG B C     1 
ATOM   7762 O O     . ARG B 2 59  ? 142.430 124.918 136.124 1.00 69.68  ? 59  ARG B O     1 
ATOM   7763 C CB    . ARG B 2 59  ? 145.151 126.231 135.149 1.00 79.78  ? 59  ARG B CB    1 
ATOM   7764 C CG    . ARG B 2 59  ? 146.578 125.765 134.865 1.00 85.18  ? 59  ARG B CG    1 
ATOM   7765 C CD    . ARG B 2 59  ? 147.092 126.253 133.515 1.00 88.95  ? 59  ARG B CD    1 
ATOM   7766 N NE    . ARG B 2 59  ? 147.139 127.709 133.449 1.00 96.16  ? 59  ARG B NE    1 
ATOM   7767 C CZ    . ARG B 2 59  ? 147.554 128.403 132.397 1.00 102.04 ? 59  ARG B CZ    1 
ATOM   7768 N NH1   . ARG B 2 59  ? 147.964 127.805 131.290 1.00 104.72 ? 59  ARG B NH1   1 
ATOM   7769 N NH2   . ARG B 2 59  ? 147.556 129.731 132.457 1.00 101.97 ? 59  ARG B NH2   1 
ATOM   7770 N N     . GLU B 2 60  ? 141.894 126.526 134.642 1.00 60.54  ? 60  GLU B N     1 
ATOM   7771 C CA    . GLU B 2 60  ? 140.543 126.764 135.130 1.00 63.10  ? 60  GLU B CA    1 
ATOM   7772 C C     . GLU B 2 60  ? 139.490 126.011 134.317 1.00 63.93  ? 60  GLU B C     1 
ATOM   7773 O O     . GLU B 2 60  ? 138.363 126.501 134.183 1.00 68.78  ? 60  GLU B O     1 
ATOM   7774 C CB    . GLU B 2 60  ? 140.248 128.267 135.115 1.00 65.04  ? 60  GLU B CB    1 
ATOM   7775 C CG    . GLU B 2 60  ? 139.255 128.755 136.165 1.00 72.56  ? 60  GLU B CG    1 
ATOM   7776 C CD    . GLU B 2 60  ? 139.806 128.695 137.578 1.00 83.11  ? 60  GLU B CD    1 
ATOM   7777 O OE1   . GLU B 2 60  ? 139.767 127.609 138.192 1.00 84.49  ? 60  GLU B OE1   1 
ATOM   7778 O OE2   . GLU B 2 60  ? 140.282 129.737 138.076 1.00 91.96  ? 60  GLU B OE2   1 
ATOM   7779 N N     . TYR B 2 61  ? 139.838 124.844 133.765 1.00 62.39  ? 61  TYR B N     1 
ATOM   7780 C CA    . TYR B 2 61  ? 139.022 124.198 132.734 1.00 60.11  ? 61  TYR B CA    1 
ATOM   7781 C C     . TYR B 2 61  ? 137.546 124.030 133.077 1.00 58.20  ? 61  TYR B C     1 
ATOM   7782 O O     . TYR B 2 61  ? 136.707 124.314 132.206 1.00 65.38  ? 61  TYR B O     1 
ATOM   7783 C CB    . TYR B 2 61  ? 139.584 122.820 132.360 1.00 54.34  ? 61  TYR B CB    1 
ATOM   7784 C CG    . TYR B 2 61  ? 138.519 121.950 131.727 1.00 51.02  ? 61  TYR B CG    1 
ATOM   7785 C CD1   . TYR B 2 61  ? 138.025 122.238 130.462 1.00 47.96  ? 61  TYR B CD1   1 
ATOM   7786 C CD2   . TYR B 2 61  ? 137.983 120.863 132.405 1.00 55.47  ? 61  TYR B CD2   1 
ATOM   7787 C CE1   . TYR B 2 61  ? 137.040 121.468 129.889 1.00 53.32  ? 61  TYR B CE1   1 
ATOM   7788 C CE2   . TYR B 2 61  ? 136.998 120.082 131.833 1.00 52.15  ? 61  TYR B CE2   1 
ATOM   7789 C CZ    . TYR B 2 61  ? 136.532 120.391 130.575 1.00 53.60  ? 61  TYR B CZ    1 
ATOM   7790 O OH    . TYR B 2 61  ? 135.549 119.625 129.994 1.00 51.33  ? 61  TYR B OH    1 
ATOM   7791 N N     . PRO B 2 62  ? 137.153 123.536 134.256 1.00 54.87  ? 62  PRO B N     1 
ATOM   7792 C CA    . PRO B 2 62  ? 135.714 123.311 134.484 1.00 59.91  ? 62  PRO B CA    1 
ATOM   7793 C C     . PRO B 2 62  ? 134.872 124.556 134.274 1.00 62.37  ? 62  PRO B C     1 
ATOM   7794 O O     . PRO B 2 62  ? 133.704 124.452 133.883 1.00 60.88  ? 62  PRO B O     1 
ATOM   7795 C CB    . PRO B 2 62  ? 135.665 122.823 135.939 1.00 72.09  ? 62  PRO B CB    1 
ATOM   7796 C CG    . PRO B 2 62  ? 136.994 122.224 136.171 1.00 67.34  ? 62  PRO B CG    1 
ATOM   7797 C CD    . PRO B 2 62  ? 137.957 123.074 135.403 1.00 64.00  ? 62  PRO B CD    1 
ATOM   7798 N N     . PHE B 2 63  ? 135.442 125.734 134.520 1.00 64.39  ? 63  PHE B N     1 
ATOM   7799 C CA    . PHE B 2 63  ? 134.743 126.999 134.349 1.00 62.91  ? 63  PHE B CA    1 
ATOM   7800 C C     . PHE B 2 63  ? 135.109 127.728 133.062 1.00 63.27  ? 63  PHE B C     1 
ATOM   7801 O O     . PHE B 2 63  ? 134.296 128.509 132.557 1.00 66.91  ? 63  PHE B O     1 
ATOM   7802 C CB    . PHE B 2 63  ? 135.028 127.915 135.543 1.00 65.59  ? 63  PHE B CB    1 
ATOM   7803 C CG    . PHE B 2 63  ? 135.100 127.192 136.859 1.00 72.19  ? 63  PHE B CG    1 
ATOM   7804 C CD1   . PHE B 2 63  ? 133.947 126.774 137.500 1.00 74.74  ? 63  PHE B CD1   1 
ATOM   7805 C CD2   . PHE B 2 63  ? 136.323 126.944 137.461 1.00 74.13  ? 63  PHE B CD2   1 
ATOM   7806 C CE1   . PHE B 2 63  ? 134.011 126.113 138.712 1.00 77.90  ? 63  PHE B CE1   1 
ATOM   7807 C CE2   . PHE B 2 63  ? 136.394 126.284 138.674 1.00 75.55  ? 63  PHE B CE2   1 
ATOM   7808 C CZ    . PHE B 2 63  ? 135.237 125.869 139.300 1.00 78.29  ? 63  PHE B CZ    1 
ATOM   7809 N N     . GLN B 2 64  ? 136.309 127.504 132.523 1.00 61.30  ? 64  GLN B N     1 
ATOM   7810 C CA    . GLN B 2 64  ? 136.772 128.161 131.308 1.00 57.21  ? 64  GLN B CA    1 
ATOM   7811 C C     . GLN B 2 64  ? 136.790 127.180 130.147 1.00 58.67  ? 64  GLN B C     1 
ATOM   7812 O O     . GLN B 2 64  ? 137.408 126.114 130.258 1.00 62.36  ? 64  GLN B O     1 
ATOM   7813 C CB    . GLN B 2 64  ? 138.167 128.751 131.510 1.00 61.01  ? 64  GLN B CB    1 
ATOM   7814 C CG    . GLN B 2 64  ? 138.215 129.902 132.493 1.00 71.67  ? 64  GLN B CG    1 
ATOM   7815 C CD    . GLN B 2 64  ? 139.553 130.612 132.488 1.00 81.80  ? 64  GLN B CD    1 
ATOM   7816 O OE1   . GLN B 2 64  ? 140.506 130.159 131.853 1.00 80.99  ? 64  GLN B OE1   1 
ATOM   7817 N NE2   . GLN B 2 64  ? 139.632 131.734 133.191 1.00 82.15  ? 64  GLN B NE2   1 
ATOM   7818 N N     . PRO B 2 65  ? 136.143 127.508 129.029 1.00 52.65  ? 65  PRO B N     1 
ATOM   7819 C CA    . PRO B 2 65  ? 136.021 126.537 127.946 1.00 50.31  ? 65  PRO B CA    1 
ATOM   7820 C C     . PRO B 2 65  ? 137.370 126.216 127.342 1.00 45.03  ? 65  PRO B C     1 
ATOM   7821 O O     . PRO B 2 65  ? 138.272 127.075 127.289 1.00 48.16  ? 65  PRO B O     1 
ATOM   7822 C CB    . PRO B 2 65  ? 135.111 127.254 126.938 1.00 56.93  ? 65  PRO B CB    1 
ATOM   7823 C CG    . PRO B 2 65  ? 135.331 128.700 127.209 1.00 58.34  ? 65  PRO B CG    1 
ATOM   7824 C CD    . PRO B 2 65  ? 135.535 128.803 128.689 1.00 56.24  ? 65  PRO B CD    1 
ATOM   7825 N N     . PRO B 2 66  ? 137.555 124.989 126.863 1.00 41.80  ? 66  PRO B N     1 
ATOM   7826 C CA    . PRO B 2 66  ? 138.796 124.635 126.169 1.00 37.49  ? 66  PRO B CA    1 
ATOM   7827 C C     . PRO B 2 66  ? 138.891 125.307 124.809 1.00 39.87  ? 66  PRO B C     1 
ATOM   7828 O O     . PRO B 2 66  ? 137.904 125.788 124.248 1.00 46.46  ? 66  PRO B O     1 
ATOM   7829 C CB    . PRO B 2 66  ? 138.697 123.115 126.027 1.00 39.26  ? 66  PRO B CB    1 
ATOM   7830 C CG    . PRO B 2 66  ? 137.237 122.853 125.998 1.00 45.63  ? 66  PRO B CG    1 
ATOM   7831 C CD    . PRO B 2 66  ? 136.622 123.853 126.932 1.00 46.99  ? 66  PRO B CD    1 
ATOM   7832 N N     . THR B 2 67  ? 140.111 125.350 124.285 1.00 38.08  ? 67  THR B N     1 
ATOM   7833 C CA    . THR B 2 67  ? 140.376 125.909 122.966 1.00 38.27  ? 67  THR B CA    1 
ATOM   7834 C C     . THR B 2 67  ? 140.660 124.788 121.973 1.00 35.60  ? 67  THR B C     1 
ATOM   7835 O O     . THR B 2 67  ? 141.486 123.911 122.238 1.00 38.51  ? 67  THR B O     1 
ATOM   7836 C CB    . THR B 2 67  ? 141.555 126.884 123.007 1.00 43.31  ? 67  THR B CB    1 
ATOM   7837 O OG1   . THR B 2 67  ? 142.731 126.204 123.461 1.00 42.23  ? 67  THR B OG1   1 
ATOM   7838 C CG2   . THR B 2 67  ? 141.257 128.050 123.938 1.00 45.16  ? 67  THR B CG2   1 
ATOM   7839 N N     . VAL B 2 68  ? 139.978 124.825 120.832 1.00 35.32  ? 68  VAL B N     1 
ATOM   7840 C CA    . VAL B 2 68  ? 140.165 123.856 119.758 1.00 30.13  ? 68  VAL B CA    1 
ATOM   7841 C C     . VAL B 2 68  ? 140.916 124.542 118.624 1.00 28.67  ? 68  VAL B C     1 
ATOM   7842 O O     . VAL B 2 68  ? 140.548 125.647 118.209 1.00 30.75  ? 68  VAL B O     1 
ATOM   7843 C CB    . VAL B 2 68  ? 138.814 123.299 119.278 1.00 32.15  ? 68  VAL B CB    1 
ATOM   7844 C CG1   . VAL B 2 68  ? 139.012 122.264 118.193 1.00 38.28  ? 68  VAL B CG1   1 
ATOM   7845 C CG2   . VAL B 2 68  ? 138.045 122.707 120.444 1.00 36.54  ? 68  VAL B CG2   1 
ATOM   7846 N N     . LYS B 2 69  ? 141.969 123.897 118.126 1.00 29.20  ? 69  LYS B N     1 
ATOM   7847 C CA    . LYS B 2 69  ? 142.846 124.513 117.139 1.00 28.29  ? 69  LYS B CA    1 
ATOM   7848 C C     . LYS B 2 69  ? 143.278 123.479 116.111 1.00 32.45  ? 69  LYS B C     1 
ATOM   7849 O O     . LYS B 2 69  ? 143.743 122.398 116.478 1.00 38.15  ? 69  LYS B O     1 
ATOM   7850 C CB    . LYS B 2 69  ? 144.071 125.126 117.829 1.00 31.63  ? 69  LYS B CB    1 
ATOM   7851 C CG    . LYS B 2 69  ? 145.111 125.710 116.897 1.00 35.57  ? 69  LYS B CG    1 
ATOM   7852 C CD    . LYS B 2 69  ? 146.261 126.307 117.688 1.00 36.13  ? 69  LYS B CD    1 
ATOM   7853 C CE    . LYS B 2 69  ? 147.283 126.965 116.775 1.00 44.41  ? 69  LYS B CE    1 
ATOM   7854 N NZ    . LYS B 2 69  ? 148.377 127.633 117.536 1.00 43.96  ? 69  LYS B NZ    1 
ATOM   7855 N N     . PHE B 2 70  ? 143.135 123.809 114.830 1.00 31.27  ? 70  PHE B N     1 
ATOM   7856 C CA    . PHE B 2 70  ? 143.588 122.922 113.765 1.00 34.31  ? 70  PHE B CA    1 
ATOM   7857 C C     . PHE B 2 70  ? 145.079 123.119 113.526 1.00 38.84  ? 70  PHE B C     1 
ATOM   7858 O O     . PHE B 2 70  ? 145.512 124.207 113.132 1.00 42.96  ? 70  PHE B O     1 
ATOM   7859 C CB    . PHE B 2 70  ? 142.809 123.176 112.475 1.00 36.51  ? 70  PHE B CB    1 
ATOM   7860 C CG    . PHE B 2 70  ? 141.468 122.504 112.429 1.00 44.41  ? 70  PHE B CG    1 
ATOM   7861 C CD1   . PHE B 2 70  ? 141.357 121.178 112.052 1.00 48.31  ? 70  PHE B CD1   1 
ATOM   7862 C CD2   . PHE B 2 70  ? 140.317 123.198 112.751 1.00 48.94  ? 70  PHE B CD2   1 
ATOM   7863 C CE1   . PHE B 2 70  ? 140.128 120.556 112.005 1.00 48.72  ? 70  PHE B CE1   1 
ATOM   7864 C CE2   . PHE B 2 70  ? 139.082 122.581 112.705 1.00 49.05  ? 70  PHE B CE2   1 
ATOM   7865 C CZ    . PHE B 2 70  ? 138.990 121.259 112.329 1.00 47.17  ? 70  PHE B CZ    1 
ATOM   7866 N N     . THR B 2 71  ? 145.865 122.068 113.759 1.00 40.00  ? 71  THR B N     1 
ATOM   7867 C CA    . THR B 2 71  ? 147.280 122.113 113.409 1.00 41.39  ? 71  THR B CA    1 
ATOM   7868 C C     . THR B 2 71  ? 147.467 122.087 111.897 1.00 47.33  ? 71  THR B C     1 
ATOM   7869 O O     . THR B 2 71  ? 148.229 122.886 111.339 1.00 58.97  ? 71  THR B O     1 
ATOM   7870 C CB    . THR B 2 71  ? 148.019 120.949 114.068 1.00 47.19  ? 71  THR B CB    1 
ATOM   7871 O OG1   . THR B 2 71  ? 147.877 121.039 115.491 1.00 48.55  ? 71  THR B OG1   1 
ATOM   7872 C CG2   . THR B 2 71  ? 149.497 120.978 113.708 1.00 52.50  ? 71  THR B CG2   1 
ATOM   7873 N N     . THR B 2 72  ? 146.775 121.177 111.216 1.00 42.28  ? 72  THR B N     1 
ATOM   7874 C CA    . THR B 2 72  ? 146.773 121.160 109.760 1.00 53.96  ? 72  THR B CA    1 
ATOM   7875 C C     . THR B 2 72  ? 145.888 122.287 109.241 1.00 63.67  ? 72  THR B C     1 
ATOM   7876 O O     . THR B 2 72  ? 144.697 122.349 109.567 1.00 66.00  ? 72  THR B O     1 
ATOM   7877 C CB    . THR B 2 72  ? 146.280 119.808 109.248 1.00 55.49  ? 72  THR B CB    1 
ATOM   7878 O OG1   . THR B 2 72  ? 147.117 118.768 109.764 1.00 59.96  ? 72  THR B OG1   1 
ATOM   7879 C CG2   . THR B 2 72  ? 146.311 119.761 107.729 1.00 65.22  ? 72  THR B CG2   1 
ATOM   7880 N N     . ARG B 2 73  ? 146.469 123.180 108.440 1.00 59.32  ? 73  ARG B N     1 
ATOM   7881 C CA    . ARG B 2 73  ? 145.729 124.324 107.921 1.00 52.63  ? 73  ARG B CA    1 
ATOM   7882 C C     . ARG B 2 73  ? 144.537 123.865 107.089 1.00 50.90  ? 73  ARG B C     1 
ATOM   7883 O O     . ARG B 2 73  ? 144.657 122.964 106.254 1.00 53.76  ? 73  ARG B O     1 
ATOM   7884 C CB    . ARG B 2 73  ? 146.659 125.208 107.088 1.00 62.64  ? 73  ARG B CB    1 
ATOM   7885 C CG    . ARG B 2 73  ? 147.479 124.447 106.061 1.00 67.65  ? 73  ARG B CG    1 
ATOM   7886 C CD    . ARG B 2 73  ? 148.484 125.356 105.368 1.00 70.81  ? 73  ARG B CD    1 
ATOM   7887 N NE    . ARG B 2 73  ? 149.488 125.872 106.292 1.00 73.86  ? 73  ARG B NE    1 
ATOM   7888 C CZ    . ARG B 2 73  ? 150.417 126.764 105.974 1.00 77.50  ? 73  ARG B CZ    1 
ATOM   7889 N NH1   . ARG B 2 73  ? 150.502 127.271 104.754 1.00 70.29  ? 73  ARG B NH1   1 
ATOM   7890 N NH2   . ARG B 2 73  ? 151.280 127.162 106.905 1.00 81.15  ? 73  ARG B NH2   1 
ATOM   7891 N N     . ILE B 2 74  ? 143.381 124.486 107.323 1.00 51.82  ? 74  ILE B N     1 
ATOM   7892 C CA    . ILE B 2 74  ? 142.138 124.125 106.654 1.00 50.48  ? 74  ILE B CA    1 
ATOM   7893 C C     . ILE B 2 74  ? 141.541 125.366 106.002 1.00 49.18  ? 74  ILE B C     1 
ATOM   7894 O O     . ILE B 2 74  ? 141.583 126.463 106.571 1.00 55.67  ? 74  ILE B O     1 
ATOM   7895 C CB    . ILE B 2 74  ? 141.132 123.481 107.632 1.00 52.34  ? 74  ILE B CB    1 
ATOM   7896 C CG1   . ILE B 2 74  ? 139.847 123.083 106.905 1.00 53.27  ? 74  ILE B CG1   1 
ATOM   7897 C CG2   . ILE B 2 74  ? 140.840 124.413 108.801 1.00 49.34  ? 74  ILE B CG2   1 
ATOM   7898 C CD1   . ILE B 2 74  ? 138.845 122.365 107.777 1.00 52.04  ? 74  ILE B CD1   1 
ATOM   7899 N N     . TYR B 2 75  ? 141.005 125.196 104.794 1.00 46.06  ? 75  TYR B N     1 
ATOM   7900 C CA    . TYR B 2 75  ? 140.337 126.278 104.073 1.00 42.97  ? 75  TYR B CA    1 
ATOM   7901 C C     . TYR B 2 75  ? 138.871 126.252 104.480 1.00 40.86  ? 75  TYR B C     1 
ATOM   7902 O O     . TYR B 2 75  ? 138.066 125.525 103.895 1.00 44.63  ? 75  TYR B O     1 
ATOM   7903 C CB    . TYR B 2 75  ? 140.504 126.110 102.567 1.00 46.80  ? 75  TYR B CB    1 
ATOM   7904 C CG    . TYR B 2 75  ? 140.160 127.337 101.745 1.00 55.70  ? 75  TYR B CG    1 
ATOM   7905 C CD1   . TYR B 2 75  ? 138.852 127.596 101.347 1.00 55.83  ? 75  TYR B CD1   1 
ATOM   7906 C CD2   . TYR B 2 75  ? 141.148 128.228 101.354 1.00 57.93  ? 75  TYR B CD2   1 
ATOM   7907 C CE1   . TYR B 2 75  ? 138.541 128.718 100.589 1.00 51.23  ? 75  TYR B CE1   1 
ATOM   7908 C CE2   . TYR B 2 75  ? 140.848 129.348 100.600 1.00 58.64  ? 75  TYR B CE2   1 
ATOM   7909 C CZ    . TYR B 2 75  ? 139.545 129.589 100.221 1.00 57.78  ? 75  TYR B CZ    1 
ATOM   7910 O OH    . TYR B 2 75  ? 139.252 130.704 99.469  1.00 62.63  ? 75  TYR B OH    1 
ATOM   7911 N N     . HIS B 2 76  ? 138.517 127.049 105.482 1.00 36.46  ? 76  HIS B N     1 
ATOM   7912 C CA    . HIS B 2 76  ? 137.174 127.009 106.032 1.00 40.64  ? 76  HIS B CA    1 
ATOM   7913 C C     . HIS B 2 76  ? 136.744 128.421 106.382 1.00 42.00  ? 76  HIS B C     1 
ATOM   7914 O O     . HIS B 2 76  ? 137.586 129.245 106.758 1.00 49.52  ? 76  HIS B O     1 
ATOM   7915 C CB    . HIS B 2 76  ? 137.119 126.120 107.282 1.00 47.98  ? 76  HIS B CB    1 
ATOM   7916 C CG    . HIS B 2 76  ? 135.757 125.586 107.585 1.00 45.38  ? 76  HIS B CG    1 
ATOM   7917 N ND1   . HIS B 2 76  ? 135.160 124.604 106.828 1.00 44.20  ? 76  HIS B ND1   1 
ATOM   7918 C CD2   . HIS B 2 76  ? 134.871 125.901 108.557 1.00 45.31  ? 76  HIS B CD2   1 
ATOM   7919 C CE1   . HIS B 2 76  ? 133.967 124.332 107.324 1.00 45.63  ? 76  HIS B CE1   1 
ATOM   7920 N NE2   . HIS B 2 76  ? 133.766 125.106 108.374 1.00 48.03  ? 76  HIS B NE2   1 
ATOM   7921 N N     . PRO B 2 77  ? 135.448 128.732 106.279 1.00 40.93  ? 77  PRO B N     1 
ATOM   7922 C CA    . PRO B 2 77  ? 134.984 130.052 106.731 1.00 46.33  ? 77  PRO B CA    1 
ATOM   7923 C C     . PRO B 2 77  ? 135.017 130.225 108.236 1.00 49.94  ? 77  PRO B C     1 
ATOM   7924 O O     . PRO B 2 77  ? 135.266 131.339 108.711 1.00 57.52  ? 77  PRO B O     1 
ATOM   7925 C CB    . PRO B 2 77  ? 133.549 130.122 106.191 1.00 48.71  ? 77  PRO B CB    1 
ATOM   7926 C CG    . PRO B 2 77  ? 133.138 128.705 106.029 1.00 51.14  ? 77  PRO B CG    1 
ATOM   7927 C CD    . PRO B 2 77  ? 134.379 127.975 105.609 1.00 45.40  ? 77  PRO B CD    1 
ATOM   7928 N N     . ASN B 2 78  ? 134.783 129.167 109.004 1.00 47.11  ? 78  ASN B N     1 
ATOM   7929 C CA    . ASN B 2 78  ? 134.655 129.283 110.448 1.00 49.79  ? 78  ASN B CA    1 
ATOM   7930 C C     . ASN B 2 78  ? 135.956 129.017 111.195 1.00 54.35  ? 78  ASN B C     1 
ATOM   7931 O O     . ASN B 2 78  ? 135.964 129.075 112.428 1.00 60.49  ? 78  ASN B O     1 
ATOM   7932 C CB    . ASN B 2 78  ? 133.568 128.333 110.956 1.00 55.49  ? 78  ASN B CB    1 
ATOM   7933 C CG    . ASN B 2 78  ? 132.261 128.492 110.210 1.00 58.90  ? 78  ASN B CG    1 
ATOM   7934 O OD1   . ASN B 2 78  ? 131.813 127.577 109.522 1.00 58.66  ? 78  ASN B OD1   1 
ATOM   7935 N ND2   . ASN B 2 78  ? 131.639 129.655 110.341 1.00 65.51  ? 78  ASN B ND2   1 
ATOM   7936 N N     . VAL B 2 79  ? 137.052 128.739 110.494 1.00 52.53  ? 79  VAL B N     1 
ATOM   7937 C CA    . VAL B 2 79  ? 138.343 128.474 111.121 1.00 46.64  ? 79  VAL B CA    1 
ATOM   7938 C C     . VAL B 2 79  ? 139.310 129.572 110.708 1.00 48.46  ? 79  VAL B C     1 
ATOM   7939 O O     . VAL B 2 79  ? 139.514 129.808 109.511 1.00 51.98  ? 79  VAL B O     1 
ATOM   7940 C CB    . VAL B 2 79  ? 138.897 127.096 110.735 1.00 41.85  ? 79  VAL B CB    1 
ATOM   7941 C CG1   . VAL B 2 79  ? 140.204 126.835 111.465 1.00 45.72  ? 79  VAL B CG1   1 
ATOM   7942 C CG2   . VAL B 2 79  ? 137.879 126.014 111.038 1.00 48.39  ? 79  VAL B CG2   1 
ATOM   7943 N N     . ASP B 2 80  ? 139.921 130.225 111.692 1.00 52.81  ? 80  ASP B N     1 
ATOM   7944 C CA    . ASP B 2 80  ? 140.883 131.277 111.413 1.00 59.20  ? 80  ASP B CA    1 
ATOM   7945 C C     . ASP B 2 80  ? 142.132 130.693 110.755 1.00 57.33  ? 80  ASP B C     1 
ATOM   7946 O O     . ASP B 2 80  ? 142.346 129.478 110.728 1.00 59.79  ? 80  ASP B O     1 
ATOM   7947 C CB    . ASP B 2 80  ? 141.250 132.016 112.697 1.00 66.04  ? 80  ASP B CB    1 
ATOM   7948 C CG    . ASP B 2 80  ? 141.670 133.446 112.442 1.00 76.81  ? 80  ASP B CG    1 
ATOM   7949 O OD1   . ASP B 2 80  ? 141.585 133.886 111.277 1.00 75.48  ? 80  ASP B OD1   1 
ATOM   7950 O OD2   . ASP B 2 80  ? 142.078 134.132 113.402 1.00 77.76  ? 80  ASP B OD2   1 
ATOM   7951 N N     . ARG B 2 81  ? 142.970 131.580 110.217 1.00 53.35  ? 81  ARG B N     1 
ATOM   7952 C CA    . ARG B 2 81  ? 144.149 131.136 109.486 1.00 56.41  ? 81  ARG B CA    1 
ATOM   7953 C C     . ARG B 2 81  ? 145.218 130.526 110.384 1.00 65.77  ? 81  ARG B C     1 
ATOM   7954 O O     . ARG B 2 81  ? 146.115 129.847 109.870 1.00 76.03  ? 81  ARG B O     1 
ATOM   7955 C CB    . ARG B 2 81  ? 144.736 132.299 108.683 1.00 58.32  ? 81  ARG B CB    1 
ATOM   7956 C CG    . ARG B 2 81  ? 145.041 133.547 109.485 1.00 68.68  ? 81  ARG B CG    1 
ATOM   7957 C CD    . ARG B 2 81  ? 145.596 134.643 108.577 1.00 71.04  ? 81  ARG B CD    1 
ATOM   7958 N NE    . ARG B 2 81  ? 144.699 134.962 107.470 1.00 71.39  ? 81  ARG B NE    1 
ATOM   7959 C CZ    . ARG B 2 81  ? 144.887 134.590 106.210 1.00 69.05  ? 81  ARG B CZ    1 
ATOM   7960 N NH1   . ARG B 2 81  ? 145.944 133.882 105.847 1.00 69.70  ? 81  ARG B NH1   1 
ATOM   7961 N NH2   . ARG B 2 81  ? 143.989 134.936 105.291 1.00 65.88  ? 81  ARG B NH2   1 
ATOM   7962 N N     . ASP B 2 82  ? 145.147 130.734 111.696 1.00 57.56  ? 82  ASP B N     1 
ATOM   7963 C CA    . ASP B 2 82  ? 146.028 130.049 112.634 1.00 55.69  ? 82  ASP B CA    1 
ATOM   7964 C C     . ASP B 2 82  ? 145.430 128.751 113.165 1.00 58.91  ? 82  ASP B C     1 
ATOM   7965 O O     . ASP B 2 82  ? 146.050 128.101 114.012 1.00 61.60  ? 82  ASP B O     1 
ATOM   7966 C CB    . ASP B 2 82  ? 146.384 130.973 113.805 1.00 61.40  ? 82  ASP B CB    1 
ATOM   7967 C CG    . ASP B 2 82  ? 145.184 131.334 114.662 1.00 68.94  ? 82  ASP B CG    1 
ATOM   7968 O OD1   . ASP B 2 82  ? 144.032 131.079 114.250 1.00 70.95  ? 82  ASP B OD1   1 
ATOM   7969 O OD2   . ASP B 2 82  ? 145.400 131.879 115.764 1.00 71.87  ? 82  ASP B OD2   1 
ATOM   7970 N N     . GLY B 2 83  ? 144.248 128.363 112.691 1.00 56.56  ? 83  GLY B N     1 
ATOM   7971 C CA    . GLY B 2 83  ? 143.599 127.143 113.118 1.00 45.25  ? 83  GLY B CA    1 
ATOM   7972 C C     . GLY B 2 83  ? 142.547 127.303 114.194 1.00 40.50  ? 83  GLY B C     1 
ATOM   7973 O O     . GLY B 2 83  ? 141.880 126.317 114.529 1.00 44.73  ? 83  GLY B O     1 
ATOM   7974 N N     . ARG B 2 84  ? 142.373 128.502 114.742 1.00 39.79  ? 84  ARG B N     1 
ATOM   7975 C CA    . ARG B 2 84  ? 141.385 128.714 115.793 1.00 41.61  ? 84  ARG B CA    1 
ATOM   7976 C C     . ARG B 2 84  ? 139.981 128.424 115.276 1.00 43.79  ? 84  ARG B C     1 
ATOM   7977 O O     . ARG B 2 84  ? 139.613 128.847 114.178 1.00 52.57  ? 84  ARG B O     1 
ATOM   7978 C CB    . ARG B 2 84  ? 141.480 130.149 116.312 1.00 55.45  ? 84  ARG B CB    1 
ATOM   7979 C CG    . ARG B 2 84  ? 140.547 130.473 117.467 1.00 63.08  ? 84  ARG B CG    1 
ATOM   7980 C CD    . ARG B 2 84  ? 140.872 131.830 118.091 1.00 72.74  ? 84  ARG B CD    1 
ATOM   7981 N NE    . ARG B 2 84  ? 139.973 132.141 119.196 1.00 79.52  ? 84  ARG B NE    1 
ATOM   7982 C CZ    . ARG B 2 84  ? 140.118 133.165 120.027 1.00 76.67  ? 84  ARG B CZ    1 
ATOM   7983 N NH1   . ARG B 2 84  ? 141.122 134.018 119.909 1.00 66.60  ? 84  ARG B NH1   1 
ATOM   7984 N NH2   . ARG B 2 84  ? 139.235 133.334 121.006 1.00 81.15  ? 84  ARG B NH2   1 
ATOM   7985 N N     . VAL B 2 85  ? 139.194 127.699 116.068 1.00 45.07  ? 85  VAL B N     1 
ATOM   7986 C CA    . VAL B 2 85  ? 137.836 127.320 115.689 1.00 46.23  ? 85  VAL B CA    1 
ATOM   7987 C C     . VAL B 2 85  ? 136.851 128.138 116.512 1.00 52.25  ? 85  VAL B C     1 
ATOM   7988 O O     . VAL B 2 85  ? 136.884 128.112 117.748 1.00 55.70  ? 85  VAL B O     1 
ATOM   7989 C CB    . VAL B 2 85  ? 137.592 125.816 115.878 1.00 42.64  ? 85  VAL B CB    1 
ATOM   7990 C CG1   . VAL B 2 85  ? 136.228 125.438 115.331 1.00 51.48  ? 85  VAL B CG1   1 
ATOM   7991 C CG2   . VAL B 2 85  ? 138.679 125.017 115.194 1.00 40.38  ? 85  VAL B CG2   1 
ATOM   7992 N N     . CYS B 2 86  ? 135.970 128.856 115.825 1.00 49.18  ? 86  CYS B N     1 
ATOM   7993 C CA    . CYS B 2 86  ? 134.966 129.701 116.466 1.00 52.16  ? 86  CYS B CA    1 
ATOM   7994 C C     . CYS B 2 86  ? 133.685 128.930 116.769 1.00 60.52  ? 86  CYS B C     1 
ATOM   7995 O O     . CYS B 2 86  ? 132.593 129.291 116.333 1.00 67.87  ? 86  CYS B O     1 
ATOM   7996 C CB    . CYS B 2 86  ? 134.688 130.913 115.590 1.00 61.79  ? 86  CYS B CB    1 
ATOM   7997 S SG    . CYS B 2 86  ? 135.952 132.182 115.739 1.00 86.04  ? 86  CYS B SG    1 
ATOM   7998 N N     . LEU B 2 87  ? 133.823 127.853 117.522 1.00 63.03  ? 87  LEU B N     1 
ATOM   7999 C CA    . LEU B 2 87  ? 132.688 127.029 117.899 1.00 63.14  ? 87  LEU B CA    1 
ATOM   8000 C C     . LEU B 2 87  ? 131.843 127.753 118.947 1.00 66.40  ? 87  LEU B C     1 
ATOM   8001 O O     . LEU B 2 87  ? 132.388 128.387 119.853 1.00 69.98  ? 87  LEU B O     1 
ATOM   8002 C CB    . LEU B 2 87  ? 133.172 125.684 118.441 1.00 60.05  ? 87  LEU B CB    1 
ATOM   8003 C CG    . LEU B 2 87  ? 132.210 124.504 118.344 1.00 61.95  ? 87  LEU B CG    1 
ATOM   8004 C CD1   . LEU B 2 87  ? 131.780 124.282 116.903 1.00 63.25  ? 87  LEU B CD1   1 
ATOM   8005 C CD2   . LEU B 2 87  ? 132.861 123.253 118.900 1.00 54.69  ? 87  LEU B CD2   1 
ATOM   8006 N N     . PRO B 2 88  ? 130.513 127.706 118.828 1.00 67.10  ? 88  PRO B N     1 
ATOM   8007 C CA    . PRO B 2 88  ? 129.678 128.433 119.799 1.00 64.65  ? 88  PRO B CA    1 
ATOM   8008 C C     . PRO B 2 88  ? 129.670 127.807 121.181 1.00 70.25  ? 88  PRO B C     1 
ATOM   8009 O O     . PRO B 2 88  ? 129.569 128.531 122.178 1.00 72.31  ? 88  PRO B O     1 
ATOM   8010 C CB    . PRO B 2 88  ? 128.288 128.402 119.148 1.00 69.13  ? 88  PRO B CB    1 
ATOM   8011 C CG    . PRO B 2 88  ? 128.305 127.176 118.297 1.00 72.65  ? 88  PRO B CG    1 
ATOM   8012 C CD    . PRO B 2 88  ? 129.708 127.067 117.771 1.00 71.14  ? 88  PRO B CD    1 
ATOM   8013 N N     . ILE B 2 89  ? 129.767 126.477 121.274 1.00 67.93  ? 89  ILE B N     1 
ATOM   8014 C CA    . ILE B 2 89  ? 129.657 125.812 122.570 1.00 61.52  ? 89  ILE B CA    1 
ATOM   8015 C C     . ILE B 2 89  ? 130.826 126.176 123.479 1.00 68.23  ? 89  ILE B C     1 
ATOM   8016 O O     . ILE B 2 89  ? 130.670 126.243 124.705 1.00 72.01  ? 89  ILE B O     1 
ATOM   8017 C CB    . ILE B 2 89  ? 129.528 124.286 122.377 1.00 56.49  ? 89  ILE B CB    1 
ATOM   8018 C CG1   . ILE B 2 89  ? 129.122 123.605 123.686 1.00 65.54  ? 89  ILE B CG1   1 
ATOM   8019 C CG2   . ILE B 2 89  ? 130.822 123.694 121.856 1.00 58.89  ? 89  ILE B CG2   1 
ATOM   8020 C CD1   . ILE B 2 89  ? 128.872 122.115 123.547 1.00 58.02  ? 89  ILE B CD1   1 
ATOM   8021 N N     . ILE B 2 90  ? 132.000 126.446 122.907 1.00 66.27  ? 90  ILE B N     1 
ATOM   8022 C CA    . ILE B 2 90  ? 133.175 126.769 123.709 1.00 62.62  ? 90  ILE B CA    1 
ATOM   8023 C C     . ILE B 2 90  ? 133.333 128.280 123.827 1.00 67.47  ? 90  ILE B C     1 
ATOM   8024 O O     . ILE B 2 90  ? 134.399 128.774 124.211 1.00 67.09  ? 90  ILE B O     1 
ATOM   8025 C CB    . ILE B 2 90  ? 134.450 126.124 123.130 1.00 60.23  ? 90  ILE B CB    1 
ATOM   8026 C CG1   . ILE B 2 90  ? 134.703 126.599 121.699 1.00 59.39  ? 90  ILE B CG1   1 
ATOM   8027 C CG2   . ILE B 2 90  ? 134.359 124.603 123.201 1.00 63.47  ? 90  ILE B CG2   1 
ATOM   8028 C CD1   . ILE B 2 90  ? 135.972 126.041 121.099 1.00 52.37  ? 90  ILE B CD1   1 
ATOM   8029 N N     . SER B 2 91  ? 132.282 129.027 123.504 1.00 71.52  ? 91  SER B N     1 
ATOM   8030 C CA    . SER B 2 91  ? 132.322 130.470 123.701 1.00 73.62  ? 91  SER B CA    1 
ATOM   8031 C C     . SER B 2 91  ? 132.276 130.803 125.185 1.00 78.30  ? 91  SER B C     1 
ATOM   8032 O O     . SER B 2 91  ? 131.628 130.111 125.975 1.00 81.91  ? 91  SER B O     1 
ATOM   8033 C CB    . SER B 2 91  ? 131.157 131.149 122.983 1.00 73.63  ? 91  SER B CB    1 
ATOM   8034 O OG    . SER B 2 91  ? 129.941 130.939 123.678 1.00 75.24  ? 91  SER B OG    1 
ATOM   8035 N N     . LYS B 2 92  ? 132.972 131.875 125.566 1.00 77.88  ? 92  LYS B N     1 
ATOM   8036 C CA    . LYS B 2 92  ? 132.905 132.344 126.943 1.00 81.27  ? 92  LYS B CA    1 
ATOM   8037 C C     . LYS B 2 92  ? 131.500 132.790 127.329 1.00 88.11  ? 92  LYS B C     1 
ATOM   8038 O O     . LYS B 2 92  ? 131.191 132.864 128.524 1.00 91.53  ? 92  LYS B O     1 
ATOM   8039 C CB    . LYS B 2 92  ? 133.900 133.488 127.152 1.00 81.72  ? 92  LYS B CB    1 
ATOM   8040 C CG    . LYS B 2 92  ? 135.356 133.076 126.994 1.00 88.86  ? 92  LYS B CG    1 
ATOM   8041 C CD    . LYS B 2 92  ? 136.268 134.284 126.826 1.00 96.50  ? 92  LYS B CD    1 
ATOM   8042 C CE    . LYS B 2 92  ? 136.123 135.269 127.977 1.00 98.06  ? 92  LYS B CE    1 
ATOM   8043 N NZ    . LYS B 2 92  ? 136.678 134.734 129.250 1.00 90.83  ? 92  LYS B NZ    1 
ATOM   8044 N N     . LYS B 2 93  ? 130.642 133.077 126.347 1.00 84.70  ? 93  LYS B N     1 
ATOM   8045 C CA    . LYS B 2 93  ? 129.309 133.586 126.650 1.00 85.91  ? 93  LYS B CA    1 
ATOM   8046 C C     . LYS B 2 93  ? 128.398 132.506 127.218 1.00 85.48  ? 93  LYS B C     1 
ATOM   8047 O O     . LYS B 2 93  ? 127.626 132.777 128.145 1.00 92.22  ? 93  LYS B O     1 
ATOM   8048 C CB    . LYS B 2 93  ? 128.683 134.187 125.391 1.00 88.06  ? 93  LYS B CB    1 
ATOM   8049 C CG    . LYS B 2 93  ? 127.335 134.847 125.613 1.00 94.43  ? 93  LYS B CG    1 
ATOM   8050 C CD    . LYS B 2 93  ? 127.448 136.018 126.570 1.00 97.89  ? 93  LYS B CD    1 
ATOM   8051 C CE    . LYS B 2 93  ? 126.150 136.800 126.622 1.00 98.51  ? 93  LYS B CE    1 
ATOM   8052 N NZ    . LYS B 2 93  ? 125.012 135.933 127.031 1.00 101.58 ? 93  LYS B NZ    1 
ATOM   8053 N N     . ASN B 2 94  ? 128.480 131.279 126.697 1.00 81.05  ? 94  ASN B N     1 
ATOM   8054 C CA    . ASN B 2 94  ? 127.529 130.250 127.096 1.00 83.48  ? 94  ASN B CA    1 
ATOM   8055 C C     . ASN B 2 94  ? 128.173 128.913 127.450 1.00 81.93  ? 94  ASN B C     1 
ATOM   8056 O O     . ASN B 2 94  ? 127.445 127.928 127.625 1.00 82.01  ? 94  ASN B O     1 
ATOM   8057 C CB    . ASN B 2 94  ? 126.479 130.039 125.996 1.00 83.07  ? 94  ASN B CB    1 
ATOM   8058 C CG    . ASN B 2 94  ? 127.096 129.822 124.629 1.00 85.49  ? 94  ASN B CG    1 
ATOM   8059 O OD1   . ASN B 2 94  ? 128.042 129.050 124.475 1.00 81.56  ? 94  ASN B OD1   1 
ATOM   8060 N ND2   . ASN B 2 94  ? 126.569 130.512 123.627 1.00 84.81  ? 94  ASN B ND2   1 
ATOM   8061 N N     . TRP B 2 95  ? 129.498 128.832 127.557 1.00 76.49  ? 95  TRP B N     1 
ATOM   8062 C CA    . TRP B 2 95  ? 130.108 127.616 128.078 1.00 68.93  ? 95  TRP B CA    1 
ATOM   8063 C C     . TRP B 2 95  ? 129.696 127.416 129.528 1.00 76.12  ? 95  TRP B C     1 
ATOM   8064 O O     . TRP B 2 95  ? 129.899 128.296 130.370 1.00 77.73  ? 95  TRP B O     1 
ATOM   8065 C CB    . TRP B 2 95  ? 131.630 127.672 127.963 1.00 67.28  ? 95  TRP B CB    1 
ATOM   8066 C CG    . TRP B 2 95  ? 132.314 126.619 128.788 1.00 67.88  ? 95  TRP B CG    1 
ATOM   8067 C CD1   . TRP B 2 95  ? 132.786 126.758 130.059 1.00 67.65  ? 95  TRP B CD1   1 
ATOM   8068 C CD2   . TRP B 2 95  ? 132.590 125.264 128.404 1.00 60.64  ? 95  TRP B CD2   1 
ATOM   8069 N NE1   . TRP B 2 95  ? 133.342 125.580 130.489 1.00 66.55  ? 95  TRP B NE1   1 
ATOM   8070 C CE2   . TRP B 2 95  ? 133.235 124.648 129.492 1.00 60.59  ? 95  TRP B CE2   1 
ATOM   8071 C CE3   . TRP B 2 95  ? 132.359 124.516 127.246 1.00 62.16  ? 95  TRP B CE3   1 
ATOM   8072 C CZ2   . TRP B 2 95  ? 133.649 123.321 129.459 1.00 62.82  ? 95  TRP B CZ2   1 
ATOM   8073 C CZ3   . TRP B 2 95  ? 132.775 123.199 127.215 1.00 65.28  ? 95  TRP B CZ3   1 
ATOM   8074 C CH2   . TRP B 2 95  ? 133.410 122.615 128.314 1.00 66.12  ? 95  TRP B CH2   1 
ATOM   8075 N N     . LYS B 2 96  ? 129.129 126.252 129.818 1.00 78.28  ? 96  LYS B N     1 
ATOM   8076 C CA    . LYS B 2 96  ? 128.666 125.911 131.152 1.00 79.30  ? 96  LYS B CA    1 
ATOM   8077 C C     . LYS B 2 96  ? 129.419 124.686 131.645 1.00 77.30  ? 96  LYS B C     1 
ATOM   8078 O O     . LYS B 2 96  ? 129.754 123.796 130.859 1.00 74.53  ? 96  LYS B O     1 
ATOM   8079 C CB    . LYS B 2 96  ? 127.155 125.660 131.162 1.00 80.83  ? 96  LYS B CB    1 
ATOM   8080 C CG    . LYS B 2 96  ? 126.335 126.932 131.012 1.00 87.39  ? 96  LYS B CG    1 
ATOM   8081 C CD    . LYS B 2 96  ? 124.865 126.642 130.760 1.00 97.00  ? 96  LYS B CD    1 
ATOM   8082 C CE    . LYS B 2 96  ? 124.637 126.086 129.360 1.00 97.94  ? 96  LYS B CE    1 
ATOM   8083 N NZ    . LYS B 2 96  ? 123.188 125.949 129.032 1.00 104.61 ? 96  LYS B NZ    1 
ATOM   8084 N N     . ALA B 2 97  ? 129.683 124.649 132.953 1.00 77.19  ? 97  ALA B N     1 
ATOM   8085 C CA    . ALA B 2 97  ? 130.514 123.596 133.529 1.00 74.32  ? 97  ALA B CA    1 
ATOM   8086 C C     . ALA B 2 97  ? 129.956 122.201 133.282 1.00 72.91  ? 97  ALA B C     1 
ATOM   8087 O O     . ALA B 2 97  ? 130.722 121.233 133.290 1.00 72.81  ? 97  ALA B O     1 
ATOM   8088 C CB    . ALA B 2 97  ? 130.682 123.829 135.030 1.00 75.77  ? 97  ALA B CB    1 
ATOM   8089 N N     . SER B 2 98  ? 128.647 122.071 133.068 1.00 72.60  ? 98  SER B N     1 
ATOM   8090 C CA    . SER B 2 98  ? 128.049 120.758 132.863 1.00 71.79  ? 98  SER B CA    1 
ATOM   8091 C C     . SER B 2 98  ? 128.336 120.183 131.482 1.00 72.21  ? 98  SER B C     1 
ATOM   8092 O O     . SER B 2 98  ? 128.166 118.974 131.287 1.00 74.07  ? 98  SER B O     1 
ATOM   8093 C CB    . SER B 2 98  ? 126.539 120.837 133.096 1.00 78.48  ? 98  SER B CB    1 
ATOM   8094 O OG    . SER B 2 98  ? 125.950 121.846 132.294 1.00 81.98  ? 98  SER B OG    1 
ATOM   8095 N N     . THR B 2 99  ? 128.773 121.002 130.531 1.00 69.96  ? 99  THR B N     1 
ATOM   8096 C CA    . THR B 2 99  ? 129.078 120.503 129.201 1.00 65.19  ? 99  THR B CA    1 
ATOM   8097 C C     . THR B 2 99  ? 130.442 119.815 129.192 1.00 64.34  ? 99  THR B C     1 
ATOM   8098 O O     . THR B 2 99  ? 131.300 120.066 130.042 1.00 69.17  ? 99  THR B O     1 
ATOM   8099 C CB    . THR B 2 99  ? 129.035 121.640 128.178 1.00 71.40  ? 99  THR B CB    1 
ATOM   8100 O OG1   . THR B 2 99  ? 130.086 122.573 128.449 1.00 70.29  ? 99  THR B OG1   1 
ATOM   8101 C CG2   . THR B 2 99  ? 127.699 122.368 128.253 1.00 77.01  ? 99  THR B CG2   1 
ATOM   8102 N N     . ARG B 2 100 ? 130.631 118.927 128.216 1.00 59.71  ? 100 ARG B N     1 
ATOM   8103 C CA    . ARG B 2 100 ? 131.790 118.046 128.162 1.00 53.26  ? 100 ARG B CA    1 
ATOM   8104 C C     . ARG B 2 100 ? 132.403 118.097 126.771 1.00 45.65  ? 100 ARG B C     1 
ATOM   8105 O O     . ARG B 2 100 ? 131.767 118.529 125.808 1.00 53.22  ? 100 ARG B O     1 
ATOM   8106 C CB    . ARG B 2 100 ? 131.418 116.599 128.511 1.00 56.40  ? 100 ARG B CB    1 
ATOM   8107 C CG    . ARG B 2 100 ? 130.688 116.449 129.831 1.00 56.69  ? 100 ARG B CG    1 
ATOM   8108 C CD    . ARG B 2 100 ? 130.318 115.000 130.107 1.00 57.08  ? 100 ARG B CD    1 
ATOM   8109 N NE    . ARG B 2 100 ? 131.489 114.154 130.302 1.00 57.80  ? 100 ARG B NE    1 
ATOM   8110 C CZ    . ARG B 2 100 ? 132.151 114.048 131.446 1.00 60.43  ? 100 ARG B CZ    1 
ATOM   8111 N NH1   . ARG B 2 100 ? 131.804 114.748 132.514 1.00 56.21  ? 100 ARG B NH1   1 
ATOM   8112 N NH2   . ARG B 2 100 ? 133.187 113.216 131.522 1.00 63.05  ? 100 ARG B NH2   1 
ATOM   8113 N N     . THR B 2 101 ? 133.653 117.635 126.673 1.00 41.87  ? 101 THR B N     1 
ATOM   8114 C CA    . THR B 2 101 ? 134.384 117.708 125.412 1.00 47.95  ? 101 THR B CA    1 
ATOM   8115 C C     . THR B 2 101 ? 133.775 116.831 124.321 1.00 51.99  ? 101 THR B C     1 
ATOM   8116 O O     . THR B 2 101 ? 133.998 117.099 123.136 1.00 56.91  ? 101 THR B O     1 
ATOM   8117 C CB    . THR B 2 101 ? 135.852 117.333 125.632 1.00 46.42  ? 101 THR B CB    1 
ATOM   8118 O OG1   . THR B 2 101 ? 136.363 118.057 126.756 1.00 48.97  ? 101 THR B OG1   1 
ATOM   8119 C CG2   . THR B 2 101 ? 136.691 117.685 124.411 1.00 51.25  ? 101 THR B CG2   1 
ATOM   8120 N N     . SER B 2 102 ? 133.014 115.795 124.682 1.00 47.21  ? 102 SER B N     1 
ATOM   8121 C CA    . SER B 2 102 ? 132.308 115.017 123.667 1.00 46.24  ? 102 SER B CA    1 
ATOM   8122 C C     . SER B 2 102 ? 131.306 115.887 122.911 1.00 49.71  ? 102 SER B C     1 
ATOM   8123 O O     . SER B 2 102 ? 131.229 115.839 121.677 1.00 53.98  ? 102 SER B O     1 
ATOM   8124 C CB    . SER B 2 102 ? 131.612 113.818 124.311 1.00 41.83  ? 102 SER B CB    1 
ATOM   8125 O OG    . SER B 2 102 ? 130.697 114.228 125.311 1.00 46.44  ? 102 SER B OG    1 
ATOM   8126 N N     . GLN B 2 103 ? 130.539 116.704 123.638 1.00 44.67  ? 103 GLN B N     1 
ATOM   8127 C CA    . GLN B 2 103 ? 129.633 117.643 122.984 1.00 43.23  ? 103 GLN B CA    1 
ATOM   8128 C C     . GLN B 2 103 ? 130.405 118.652 122.147 1.00 49.08  ? 103 GLN B C     1 
ATOM   8129 O O     . GLN B 2 103 ? 129.955 119.055 121.066 1.00 51.96  ? 103 GLN B O     1 
ATOM   8130 C CB    . GLN B 2 103 ? 128.780 118.364 124.027 1.00 48.11  ? 103 GLN B CB    1 
ATOM   8131 C CG    . GLN B 2 103 ? 127.940 117.449 124.895 1.00 51.56  ? 103 GLN B CG    1 
ATOM   8132 C CD    . GLN B 2 103 ? 127.130 118.215 125.922 1.00 61.52  ? 103 GLN B CD    1 
ATOM   8133 O OE1   . GLN B 2 103 ? 127.456 119.349 126.268 1.00 58.76  ? 103 GLN B OE1   1 
ATOM   8134 N NE2   . GLN B 2 103 ? 126.061 117.600 126.411 1.00 63.38  ? 103 GLN B NE2   1 
ATOM   8135 N N     . VAL B 2 104 ? 131.574 119.070 122.632 1.00 43.86  ? 104 VAL B N     1 
ATOM   8136 C CA    . VAL B 2 104 ? 132.401 120.013 121.889 1.00 40.55  ? 104 VAL B CA    1 
ATOM   8137 C C     . VAL B 2 104 ? 132.819 119.415 120.554 1.00 43.45  ? 104 VAL B C     1 
ATOM   8138 O O     . VAL B 2 104 ? 132.758 120.073 119.510 1.00 53.71  ? 104 VAL B O     1 
ATOM   8139 C CB    . VAL B 2 104 ? 133.620 120.426 122.729 1.00 42.47  ? 104 VAL B CB    1 
ATOM   8140 C CG1   . VAL B 2 104 ? 134.563 121.264 121.898 1.00 50.64  ? 104 VAL B CG1   1 
ATOM   8141 C CG2   . VAL B 2 104 ? 133.167 121.178 123.968 1.00 51.70  ? 104 VAL B CG2   1 
ATOM   8142 N N     . LEU B 2 105 ? 133.245 118.154 120.565 1.00 39.58  ? 105 LEU B N     1 
ATOM   8143 C CA    . LEU B 2 105 ? 133.666 117.520 119.322 1.00 43.86  ? 105 LEU B CA    1 
ATOM   8144 C C     . LEU B 2 105 ? 132.480 117.203 118.416 1.00 50.25  ? 105 LEU B C     1 
ATOM   8145 O O     . LEU B 2 105 ? 132.626 117.222 117.190 1.00 53.61  ? 105 LEU B O     1 
ATOM   8146 C CB    . LEU B 2 105 ? 134.491 116.274 119.633 1.00 40.23  ? 105 LEU B CB    1 
ATOM   8147 C CG    . LEU B 2 105 ? 135.798 116.649 120.341 1.00 45.06  ? 105 LEU B CG    1 
ATOM   8148 C CD1   . LEU B 2 105 ? 136.511 115.426 120.894 1.00 51.55  ? 105 LEU B CD1   1 
ATOM   8149 C CD2   . LEU B 2 105 ? 136.715 117.436 119.407 1.00 42.75  ? 105 LEU B CD2   1 
ATOM   8150 N N     . GLU B 2 106 ? 131.297 116.953 118.984 1.00 50.46  ? 106 GLU B N     1 
ATOM   8151 C CA    . GLU B 2 106 ? 130.098 116.828 118.153 1.00 50.01  ? 106 GLU B CA    1 
ATOM   8152 C C     . GLU B 2 106 ? 129.803 118.132 117.419 1.00 57.30  ? 106 GLU B C     1 
ATOM   8153 O O     . GLU B 2 106 ? 129.550 118.139 116.205 1.00 59.61  ? 106 GLU B O     1 
ATOM   8154 C CB    . GLU B 2 106 ? 128.900 116.415 119.009 1.00 47.52  ? 106 GLU B CB    1 
ATOM   8155 C CG    . GLU B 2 106 ? 128.791 114.925 119.270 1.00 58.63  ? 106 GLU B CG    1 
ATOM   8156 C CD    . GLU B 2 106 ? 128.367 114.138 118.042 1.00 67.68  ? 106 GLU B CD    1 
ATOM   8157 O OE1   . GLU B 2 106 ? 127.741 114.724 117.134 1.00 64.95  ? 106 GLU B OE1   1 
ATOM   8158 O OE2   . GLU B 2 106 ? 128.661 112.925 117.989 1.00 73.14  ? 106 GLU B OE2   1 
ATOM   8159 N N     . ALA B 2 107 ? 129.840 119.252 118.146 1.00 50.68  ? 107 ALA B N     1 
ATOM   8160 C CA    . ALA B 2 107 ? 129.614 120.553 117.523 1.00 48.18  ? 107 ALA B CA    1 
ATOM   8161 C C     . ALA B 2 107 ? 130.692 120.868 116.492 1.00 51.11  ? 107 ALA B C     1 
ATOM   8162 O O     . ALA B 2 107 ? 130.402 121.451 115.443 1.00 51.70  ? 107 ALA B O     1 
ATOM   8163 C CB    . ALA B 2 107 ? 129.552 121.643 118.591 1.00 47.55  ? 107 ALA B CB    1 
ATOM   8164 N N     . LEU B 2 108 ? 131.943 120.493 116.771 1.00 49.27  ? 108 LEU B N     1 
ATOM   8165 C CA    . LEU B 2 108 ? 133.020 120.715 115.810 1.00 47.67  ? 108 LEU B CA    1 
ATOM   8166 C C     . LEU B 2 108 ? 132.808 119.902 114.538 1.00 49.26  ? 108 LEU B C     1 
ATOM   8167 O O     . LEU B 2 108 ? 133.020 120.402 113.426 1.00 54.19  ? 108 LEU B O     1 
ATOM   8168 C CB    . LEU B 2 108 ? 134.368 120.376 116.440 1.00 45.48  ? 108 LEU B CB    1 
ATOM   8169 C CG    . LEU B 2 108 ? 135.546 120.454 115.474 1.00 40.91  ? 108 LEU B CG    1 
ATOM   8170 C CD1   . LEU B 2 108 ? 135.747 121.878 114.996 1.00 42.03  ? 108 LEU B CD1   1 
ATOM   8171 C CD2   . LEU B 2 108 ? 136.800 119.932 116.134 1.00 41.59  ? 108 LEU B CD2   1 
ATOM   8172 N N     . ASN B 2 109 ? 132.407 118.637 114.682 1.00 48.90  ? 109 ASN B N     1 
ATOM   8173 C CA    . ASN B 2 109 ? 132.135 117.817 113.506 1.00 51.62  ? 109 ASN B CA    1 
ATOM   8174 C C     . ASN B 2 109 ? 130.998 118.407 112.684 1.00 53.73  ? 109 ASN B C     1 
ATOM   8175 O O     . ASN B 2 109 ? 131.072 118.453 111.449 1.00 57.45  ? 109 ASN B O     1 
ATOM   8176 C CB    . ASN B 2 109 ? 131.806 116.386 113.926 1.00 54.02  ? 109 ASN B CB    1 
ATOM   8177 C CG    . ASN B 2 109 ? 131.601 115.467 112.743 1.00 59.64  ? 109 ASN B CG    1 
ATOM   8178 O OD1   . ASN B 2 109 ? 132.326 115.541 111.753 1.00 58.53  ? 109 ASN B OD1   1 
ATOM   8179 N ND2   . ASN B 2 109 ? 130.602 114.598 112.835 1.00 60.16  ? 109 ASN B ND2   1 
ATOM   8180 N N     . MET B 2 110 ? 129.944 118.880 113.352 1.00 50.27  ? 110 MET B N     1 
ATOM   8181 C CA    . MET B 2 110 ? 128.839 119.492 112.621 1.00 50.23  ? 110 MET B CA    1 
ATOM   8182 C C     . MET B 2 110 ? 129.241 120.814 111.979 1.00 55.13  ? 110 MET B C     1 
ATOM   8183 O O     . MET B 2 110 ? 128.689 121.187 110.938 1.00 60.25  ? 110 MET B O     1 
ATOM   8184 C CB    . MET B 2 110 ? 127.637 119.690 113.542 1.00 51.62  ? 110 MET B CB    1 
ATOM   8185 C CG    . MET B 2 110 ? 127.029 118.388 114.031 1.00 61.38  ? 110 MET B CG    1 
ATOM   8186 S SD    . MET B 2 110 ? 126.832 117.158 112.724 1.00 82.30  ? 110 MET B SD    1 
ATOM   8187 C CE    . MET B 2 110 ? 125.709 117.997 111.608 1.00 65.24  ? 110 MET B CE    1 
ATOM   8188 N N     . LEU B 2 111 ? 130.176 121.545 112.589 1.00 50.64  ? 111 LEU B N     1 
ATOM   8189 C CA    . LEU B 2 111 ? 130.644 122.792 111.994 1.00 44.19  ? 111 LEU B CA    1 
ATOM   8190 C C     . LEU B 2 111 ? 131.488 122.530 110.755 1.00 42.29  ? 111 LEU B C     1 
ATOM   8191 O O     . LEU B 2 111 ? 131.348 123.224 109.742 1.00 52.92  ? 111 LEU B O     1 
ATOM   8192 C CB    . LEU B 2 111 ? 131.437 123.595 113.021 1.00 48.75  ? 111 LEU B CB    1 
ATOM   8193 C CG    . LEU B 2 111 ? 131.928 124.962 112.551 1.00 59.77  ? 111 LEU B CG    1 
ATOM   8194 C CD1   . LEU B 2 111 ? 130.761 125.929 112.411 1.00 62.17  ? 111 LEU B CD1   1 
ATOM   8195 C CD2   . LEU B 2 111 ? 132.983 125.513 113.498 1.00 59.60  ? 111 LEU B CD2   1 
ATOM   8196 N N     . VAL B 2 112 ? 132.370 121.532 110.817 1.00 37.57  ? 112 VAL B N     1 
ATOM   8197 C CA    . VAL B 2 112 ? 133.186 121.192 109.657 1.00 39.22  ? 112 VAL B CA    1 
ATOM   8198 C C     . VAL B 2 112 ? 132.327 120.612 108.538 1.00 49.70  ? 112 VAL B C     1 
ATOM   8199 O O     . VAL B 2 112 ? 132.564 120.893 107.356 1.00 54.71  ? 112 VAL B O     1 
ATOM   8200 C CB    . VAL B 2 112 ? 134.314 120.229 110.064 1.00 40.05  ? 112 VAL B CB    1 
ATOM   8201 C CG1   . VAL B 2 112 ? 135.102 119.780 108.848 1.00 39.61  ? 112 VAL B CG1   1 
ATOM   8202 C CG2   . VAL B 2 112 ? 135.231 120.888 111.083 1.00 45.52  ? 112 VAL B CG2   1 
ATOM   8203 N N     . ASN B 2 113 ? 131.313 119.811 108.878 1.00 52.76  ? 113 ASN B N     1 
ATOM   8204 C CA    . ASN B 2 113 ? 130.464 119.193 107.867 1.00 51.89  ? 113 ASN B CA    1 
ATOM   8205 C C     . ASN B 2 113 ? 129.313 120.077 107.410 1.00 51.08  ? 113 ASN B C     1 
ATOM   8206 O O     . ASN B 2 113 ? 128.678 119.763 106.396 1.00 51.63  ? 113 ASN B O     1 
ATOM   8207 C CB    . ASN B 2 113 ? 129.897 117.869 108.385 1.00 48.65  ? 113 ASN B CB    1 
ATOM   8208 C CG    . ASN B 2 113 ? 130.953 116.803 108.518 1.00 60.52  ? 113 ASN B CG    1 
ATOM   8209 O OD1   . ASN B 2 113 ? 131.996 116.865 107.871 1.00 65.55  ? 113 ASN B OD1   1 
ATOM   8210 N ND2   . ASN B 2 113 ? 130.692 115.813 109.360 1.00 65.88  ? 113 ASN B ND2   1 
ATOM   8211 N N     . GLN B 2 114 ? 129.025 121.164 108.118 1.00 48.53  ? 114 GLN B N     1 
ATOM   8212 C CA    . GLN B 2 114 ? 127.912 122.052 107.778 1.00 50.62  ? 114 GLN B CA    1 
ATOM   8213 C C     . GLN B 2 114 ? 128.294 123.484 108.117 1.00 53.45  ? 114 GLN B C     1 
ATOM   8214 O O     . GLN B 2 114 ? 127.874 124.032 109.143 1.00 58.52  ? 114 GLN B O     1 
ATOM   8215 C CB    . GLN B 2 114 ? 126.636 121.639 108.514 1.00 60.51  ? 114 GLN B CB    1 
ATOM   8216 C CG    . GLN B 2 114 ? 125.373 122.329 108.026 1.00 63.55  ? 114 GLN B CG    1 
ATOM   8217 C CD    . GLN B 2 114 ? 124.539 121.447 107.117 1.00 73.13  ? 114 GLN B CD    1 
ATOM   8218 O OE1   . GLN B 2 114 ? 124.142 120.345 107.495 1.00 71.03  ? 114 GLN B OE1   1 
ATOM   8219 N NE2   . GLN B 2 114 ? 124.268 121.928 105.911 1.00 74.24  ? 114 GLN B NE2   1 
ATOM   8220 N N     . PRO B 2 115 ? 129.108 124.122 107.278 1.00 56.73  ? 115 PRO B N     1 
ATOM   8221 C CA    . PRO B 2 115 ? 129.482 125.522 107.529 1.00 56.14  ? 115 PRO B CA    1 
ATOM   8222 C C     . PRO B 2 115 ? 128.256 126.423 107.587 1.00 62.98  ? 115 PRO B C     1 
ATOM   8223 O O     . PRO B 2 115 ? 127.355 126.328 106.750 1.00 68.60  ? 115 PRO B O     1 
ATOM   8224 C CB    . PRO B 2 115 ? 130.382 125.865 106.335 1.00 50.33  ? 115 PRO B CB    1 
ATOM   8225 C CG    . PRO B 2 115 ? 130.862 124.554 105.822 1.00 48.09  ? 115 PRO B CG    1 
ATOM   8226 C CD    . PRO B 2 115 ? 129.747 123.589 106.064 1.00 57.27  ? 115 PRO B CD    1 
ATOM   8227 N N     . GLU B 2 116 ? 128.224 127.296 108.594 1.00 64.13  ? 116 GLU B N     1 
ATOM   8228 C CA    . GLU B 2 116 ? 127.197 128.322 108.686 1.00 68.38  ? 116 GLU B CA    1 
ATOM   8229 C C     . GLU B 2 116 ? 127.847 129.670 108.407 1.00 71.42  ? 116 GLU B C     1 
ATOM   8230 O O     . GLU B 2 116 ? 128.511 130.228 109.293 1.00 71.57  ? 116 GLU B O     1 
ATOM   8231 C CB    . GLU B 2 116 ? 126.531 128.318 110.065 1.00 79.26  ? 116 GLU B CB    1 
ATOM   8232 C CG    . GLU B 2 116 ? 125.467 129.397 110.241 1.00 83.47  ? 116 GLU B CG    1 
ATOM   8233 C CD    . GLU B 2 116 ? 124.739 129.298 111.568 1.00 94.93  ? 116 GLU B CD    1 
ATOM   8234 O OE1   . GLU B 2 116 ? 124.823 128.235 112.218 1.00 92.68  ? 116 GLU B OE1   1 
ATOM   8235 O OE2   . GLU B 2 116 ? 124.084 130.285 111.964 1.00 96.98  ? 116 GLU B OE2   1 
ATOM   8236 N N     . PRO B 2 117 ? 127.698 130.233 107.204 1.00 78.29  ? 117 PRO B N     1 
ATOM   8237 C CA    . PRO B 2 117 ? 128.428 131.469 106.875 1.00 80.53  ? 117 PRO B CA    1 
ATOM   8238 C C     . PRO B 2 117 ? 128.007 132.672 107.699 1.00 81.44  ? 117 PRO B C     1 
ATOM   8239 O O     . PRO B 2 117 ? 128.730 133.674 107.705 1.00 82.21  ? 117 PRO B O     1 
ATOM   8240 C CB    . PRO B 2 117 ? 128.126 131.671 105.382 1.00 73.50  ? 117 PRO B CB    1 
ATOM   8241 C CG    . PRO B 2 117 ? 126.882 130.898 105.130 1.00 73.75  ? 117 PRO B CG    1 
ATOM   8242 C CD    . PRO B 2 117 ? 126.911 129.729 106.065 1.00 77.11  ? 117 PRO B CD    1 
ATOM   8243 N N     . GLY B 2 118 ? 126.874 132.607 108.397 1.00 77.50  ? 118 GLY B N     1 
ATOM   8244 C CA    . GLY B 2 118 ? 126.439 133.693 109.254 1.00 75.47  ? 118 GLY B CA    1 
ATOM   8245 C C     . GLY B 2 118 ? 127.297 133.936 110.478 1.00 83.07  ? 118 GLY B C     1 
ATOM   8246 O O     . GLY B 2 118 ? 127.039 134.896 111.210 1.00 85.22  ? 118 GLY B O     1 
ATOM   8247 N N     . GLN B 2 119 ? 128.316 133.105 110.714 1.00 85.15  ? 119 GLN B N     1 
ATOM   8248 C CA    . GLN B 2 119 ? 129.254 133.263 111.823 1.00 87.05  ? 119 GLN B CA    1 
ATOM   8249 C C     . GLN B 2 119 ? 130.662 133.355 111.238 1.00 79.19  ? 119 GLN B C     1 
ATOM   8250 O O     . GLN B 2 119 ? 131.465 132.420 111.362 1.00 74.77  ? 119 GLN B O     1 
ATOM   8251 C CB    . GLN B 2 119 ? 129.141 132.104 112.812 1.00 88.79  ? 119 GLN B CB    1 
ATOM   8252 C CG    . GLN B 2 119 ? 127.751 131.935 113.426 1.00 91.33  ? 119 GLN B CG    1 
ATOM   8253 C CD    . GLN B 2 119 ? 127.458 132.957 114.508 1.00 95.73  ? 119 GLN B CD    1 
ATOM   8254 O OE1   . GLN B 2 119 ? 127.667 132.697 115.694 1.00 93.71  ? 119 GLN B OE1   1 
ATOM   8255 N NE2   . GLN B 2 119 ? 126.975 134.127 114.108 1.00 94.18  ? 119 GLN B NE2   1 
ATOM   8256 N N     . PRO B 2 120 ? 130.991 134.471 110.591 1.00 73.38  ? 120 PRO B N     1 
ATOM   8257 C CA    . PRO B 2 120 ? 132.240 134.540 109.829 1.00 69.93  ? 120 PRO B CA    1 
ATOM   8258 C C     . PRO B 2 120 ? 133.462 134.648 110.724 1.00 69.84  ? 120 PRO B C     1 
ATOM   8259 O O     . PRO B 2 120 ? 133.416 135.196 111.828 1.00 73.79  ? 120 PRO B O     1 
ATOM   8260 C CB    . PRO B 2 120 ? 132.064 135.811 108.994 1.00 69.29  ? 120 PRO B CB    1 
ATOM   8261 C CG    . PRO B 2 120 ? 131.235 136.688 109.871 1.00 72.13  ? 120 PRO B CG    1 
ATOM   8262 C CD    . PRO B 2 120 ? 130.281 135.763 110.597 1.00 73.46  ? 120 PRO B CD    1 
ATOM   8263 N N     . VAL B 2 121 ? 134.566 134.102 110.222 1.00 64.24  ? 121 VAL B N     1 
ATOM   8264 C CA    . VAL B 2 121 ? 135.892 134.299 110.793 1.00 60.27  ? 121 VAL B CA    1 
ATOM   8265 C C     . VAL B 2 121 ? 136.773 134.823 109.671 1.00 57.08  ? 121 VAL B C     1 
ATOM   8266 O O     . VAL B 2 121 ? 137.480 135.826 109.827 1.00 68.35  ? 121 VAL B O     1 
ATOM   8267 C CB    . VAL B 2 121 ? 136.450 133.002 111.400 1.00 62.23  ? 121 VAL B CB    1 
ATOM   8268 C CG1   . VAL B 2 121 ? 137.749 133.276 112.142 1.00 66.42  ? 121 VAL B CG1   1 
ATOM   8269 C CG2   . VAL B 2 121 ? 135.426 132.372 112.320 1.00 61.41  ? 121 VAL B CG2   1 
ATOM   8270 N N     . ARG B 2 122 ? 136.750 134.122 108.542 1.00 50.14  ? 122 ARG B N     1 
ATOM   8271 C CA    . ARG B 2 122 ? 137.338 134.587 107.291 1.00 54.76  ? 122 ARG B CA    1 
ATOM   8272 C C     . ARG B 2 122 ? 136.172 135.015 106.406 1.00 64.22  ? 122 ARG B C     1 
ATOM   8273 O O     . ARG B 2 122 ? 135.532 134.194 105.748 1.00 61.76  ? 122 ARG B O     1 
ATOM   8274 C CB    . ARG B 2 122 ? 138.186 133.495 106.655 1.00 50.69  ? 122 ARG B CB    1 
ATOM   8275 C CG    . ARG B 2 122 ? 139.255 132.955 107.579 1.00 46.22  ? 122 ARG B CG    1 
ATOM   8276 C CD    . ARG B 2 122 ? 139.912 131.711 107.015 1.00 46.79  ? 122 ARG B CD    1 
ATOM   8277 N NE    . ARG B 2 122 ? 140.788 132.004 105.890 1.00 52.20  ? 122 ARG B NE    1 
ATOM   8278 C CZ    . ARG B 2 122 ? 141.636 131.133 105.360 1.00 64.07  ? 122 ARG B CZ    1 
ATOM   8279 N NH1   . ARG B 2 122 ? 141.758 129.906 105.841 1.00 67.16  ? 122 ARG B NH1   1 
ATOM   8280 N NH2   . ARG B 2 122 ? 142.382 131.502 104.324 1.00 66.72  ? 122 ARG B NH2   1 
ATOM   8281 N N     . LEU B 2 123 ? 135.884 136.321 106.411 1.00 71.21  ? 123 LEU B N     1 
ATOM   8282 C CA    . LEU B 2 123 ? 134.701 136.832 105.724 1.00 67.42  ? 123 LEU B CA    1 
ATOM   8283 C C     . LEU B 2 123 ? 134.787 136.639 104.217 1.00 64.55  ? 123 LEU B C     1 
ATOM   8284 O O     . LEU B 2 123 ? 133.758 136.429 103.563 1.00 68.23  ? 123 LEU B O     1 
ATOM   8285 C CB    . LEU B 2 123 ? 134.500 138.310 106.059 1.00 62.40  ? 123 LEU B CB    1 
ATOM   8286 C CG    . LEU B 2 123 ? 133.207 138.961 105.569 1.00 61.49  ? 123 LEU B CG    1 
ATOM   8287 C CD1   . LEU B 2 123 ? 131.999 138.216 106.108 1.00 67.67  ? 123 LEU B CD1   1 
ATOM   8288 C CD2   . LEU B 2 123 ? 133.168 140.417 105.985 1.00 60.52  ? 123 LEU B CD2   1 
ATOM   8289 N N     . GLU B 2 124 ? 135.991 136.717 103.645 1.00 57.56  ? 124 GLU B N     1 
ATOM   8290 C CA    . GLU B 2 124 ? 136.132 136.524 102.206 1.00 63.99  ? 124 GLU B CA    1 
ATOM   8291 C C     . GLU B 2 124 ? 135.749 135.108 101.799 1.00 68.60  ? 124 GLU B C     1 
ATOM   8292 O O     . GLU B 2 124 ? 135.104 134.903 100.763 1.00 74.86  ? 124 GLU B O     1 
ATOM   8293 C CB    . GLU B 2 124 ? 137.559 136.846 101.767 1.00 66.36  ? 124 GLU B CB    1 
ATOM   8294 C CG    . GLU B 2 124 ? 137.951 138.312 101.923 1.00 79.24  ? 124 GLU B CG    1 
ATOM   8295 C CD    . GLU B 2 124 ? 137.141 139.249 101.039 1.00 87.36  ? 124 GLU B CD    1 
ATOM   8296 O OE1   . GLU B 2 124 ? 135.953 139.494 101.340 1.00 82.79  ? 124 GLU B OE1   1 
ATOM   8297 O OE2   . GLU B 2 124 ? 137.696 139.747 100.039 1.00 89.70  ? 124 GLU B OE2   1 
ATOM   8298 N N     . LEU B 2 125 ? 136.127 134.117 102.609 1.00 63.36  ? 125 LEU B N     1 
ATOM   8299 C CA    . LEU B 2 125 ? 135.719 132.744 102.330 1.00 59.39  ? 125 LEU B CA    1 
ATOM   8300 C C     . LEU B 2 125 ? 134.207 132.585 102.431 1.00 64.23  ? 125 LEU B C     1 
ATOM   8301 O O     . LEU B 2 125 ? 133.606 131.847 101.645 1.00 70.62  ? 125 LEU B O     1 
ATOM   8302 C CB    . LEU B 2 125 ? 136.430 131.778 103.276 1.00 51.99  ? 125 LEU B CB    1 
ATOM   8303 C CG    . LEU B 2 125 ? 137.780 131.225 102.814 1.00 51.26  ? 125 LEU B CG    1 
ATOM   8304 C CD1   . LEU B 2 125 ? 138.806 132.332 102.599 1.00 60.12  ? 125 LEU B CD1   1 
ATOM   8305 C CD2   . LEU B 2 125 ? 138.305 130.200 103.800 1.00 51.76  ? 125 LEU B CD2   1 
ATOM   8306 N N     . ALA B 2 126 ? 133.571 133.272 103.385 1.00 62.07  ? 126 ALA B N     1 
ATOM   8307 C CA    . ALA B 2 126 ? 132.114 133.214 103.489 1.00 68.46  ? 126 ALA B CA    1 
ATOM   8308 C C     . ALA B 2 126 ? 131.442 133.837 102.271 1.00 67.73  ? 126 ALA B C     1 
ATOM   8309 O O     . ALA B 2 126 ? 130.453 133.301 101.754 1.00 69.82  ? 126 ALA B O     1 
ATOM   8310 C CB    . ALA B 2 126 ? 131.646 133.908 104.768 1.00 69.98  ? 126 ALA B CB    1 
ATOM   8311 N N     . GLU B 2 127 ? 131.953 134.980 101.810 1.00 65.27  ? 127 GLU B N     1 
ATOM   8312 C CA    . GLU B 2 127 ? 131.406 135.606 100.610 1.00 64.73  ? 127 GLU B CA    1 
ATOM   8313 C C     . GLU B 2 127 ? 131.583 134.706 99.395  1.00 68.59  ? 127 GLU B C     1 
ATOM   8314 O O     . GLU B 2 127 ? 130.678 134.586 98.561  1.00 76.38  ? 127 GLU B O     1 
ATOM   8315 C CB    . GLU B 2 127 ? 132.073 136.964 100.383 1.00 67.43  ? 127 GLU B CB    1 
ATOM   8316 C CG    . GLU B 2 127 ? 132.070 137.451 98.938  1.00 74.79  ? 127 GLU B CG    1 
ATOM   8317 C CD    . GLU B 2 127 ? 130.763 138.105 98.527  1.00 79.44  ? 127 GLU B CD    1 
ATOM   8318 O OE1   . GLU B 2 127 ? 129.840 138.189 99.363  1.00 83.52  ? 127 GLU B OE1   1 
ATOM   8319 O OE2   . GLU B 2 127 ? 130.663 138.539 97.360  1.00 77.76  ? 127 GLU B OE2   1 
ATOM   8320 N N     . GLN B 2 128 ? 132.744 134.061 99.282  1.00 65.57  ? 128 GLN B N     1 
ATOM   8321 C CA    . GLN B 2 128 ? 132.970 133.113 98.197  1.00 63.47  ? 128 GLN B CA    1 
ATOM   8322 C C     . GLN B 2 128 ? 132.002 131.939 98.284  1.00 65.72  ? 128 GLN B C     1 
ATOM   8323 O O     . GLN B 2 128 ? 131.473 131.478 97.266  1.00 70.07  ? 128 GLN B O     1 
ATOM   8324 C CB    . GLN B 2 128 ? 134.420 132.635 98.235  1.00 55.36  ? 128 GLN B CB    1 
ATOM   8325 C CG    . GLN B 2 128 ? 134.834 131.765 97.076  1.00 57.75  ? 128 GLN B CG    1 
ATOM   8326 C CD    . GLN B 2 128 ? 136.328 131.510 97.055  1.00 61.69  ? 128 GLN B CD    1 
ATOM   8327 O OE1   . GLN B 2 128 ? 136.833 130.643 97.766  1.00 61.56  ? 128 GLN B OE1   1 
ATOM   8328 N NE2   . GLN B 2 128 ? 137.045 132.273 96.241  1.00 64.92  ? 128 GLN B NE2   1 
ATOM   8329 N N     . LEU B 2 129 ? 131.763 131.436 99.495  1.00 66.16  ? 129 LEU B N     1 
ATOM   8330 C CA    . LEU B 2 129 ? 130.830 130.329 99.671  1.00 70.12  ? 129 LEU B CA    1 
ATOM   8331 C C     . LEU B 2 129 ? 129.413 130.724 99.274  1.00 71.25  ? 129 LEU B C     1 
ATOM   8332 O O     . LEU B 2 129 ? 128.698 129.942 98.638  1.00 75.24  ? 129 LEU B O     1 
ATOM   8333 C CB    . LEU B 2 129 ? 130.866 129.849 101.120 1.00 72.25  ? 129 LEU B CB    1 
ATOM   8334 C CG    . LEU B 2 129 ? 129.799 128.844 101.554 1.00 78.92  ? 129 LEU B CG    1 
ATOM   8335 C CD1   . LEU B 2 129 ? 129.972 127.519 100.823 1.00 75.95  ? 129 LEU B CD1   1 
ATOM   8336 C CD2   . LEU B 2 129 ? 129.847 128.647 103.063 1.00 71.07  ? 129 LEU B CD2   1 
ATOM   8337 N N     . THR B 2 130 ? 128.986 131.933 99.640  1.00 67.91  ? 130 THR B N     1 
ATOM   8338 C CA    . THR B 2 130 ? 127.598 132.304 99.392  1.00 72.99  ? 130 THR B CA    1 
ATOM   8339 C C     . THR B 2 130 ? 127.369 132.737 97.943  1.00 73.63  ? 130 THR B C     1 
ATOM   8340 O O     . THR B 2 130 ? 126.291 132.492 97.392  1.00 77.17  ? 130 THR B O     1 
ATOM   8341 C CB    . THR B 2 130 ? 127.149 133.395 100.376 1.00 76.98  ? 130 THR B CB    1 
ATOM   8342 O OG1   . THR B 2 130 ? 125.748 133.651 100.210 1.00 82.27  ? 130 THR B OG1   1 
ATOM   8343 C CG2   . THR B 2 130 ? 127.921 134.690 100.170 1.00 76.47  ? 130 THR B CG2   1 
ATOM   8344 N N     . GLN B 2 131 ? 128.364 133.356 97.298  1.00 69.67  ? 131 GLN B N     1 
ATOM   8345 C CA    . GLN B 2 131 ? 128.149 133.909 95.964  1.00 70.56  ? 131 GLN B CA    1 
ATOM   8346 C C     . GLN B 2 131 ? 128.529 132.960 94.836  1.00 72.52  ? 131 GLN B C     1 
ATOM   8347 O O     . GLN B 2 131 ? 127.821 132.905 93.824  1.00 77.35  ? 131 GLN B O     1 
ATOM   8348 C CB    . GLN B 2 131 ? 128.929 135.215 95.796  1.00 73.98  ? 131 GLN B CB    1 
ATOM   8349 C CG    . GLN B 2 131 ? 128.449 136.334 96.699  1.00 78.43  ? 131 GLN B CG    1 
ATOM   8350 C CD    . GLN B 2 131 ? 126.962 136.605 96.570  1.00 79.06  ? 131 GLN B CD    1 
ATOM   8351 O OE1   . GLN B 2 131 ? 126.257 136.720 97.570  1.00 74.40  ? 131 GLN B OE1   1 
ATOM   8352 N NE2   . GLN B 2 131 ? 126.478 136.720 95.338  1.00 77.55  ? 131 GLN B NE2   1 
ATOM   8353 N N     . ASP B 2 132 ? 129.629 132.224 94.970  1.00 70.77  ? 132 ASP B N     1 
ATOM   8354 C CA    . ASP B 2 132 ? 130.032 131.219 93.984  1.00 68.04  ? 132 ASP B CA    1 
ATOM   8355 C C     . ASP B 2 132 ? 130.491 129.971 94.721  1.00 67.28  ? 132 ASP B C     1 
ATOM   8356 O O     . ASP B 2 132 ? 131.685 129.654 94.768  1.00 66.82  ? 132 ASP B O     1 
ATOM   8357 C CB    . ASP B 2 132 ? 131.114 131.756 93.040  1.00 68.13  ? 132 ASP B CB    1 
ATOM   8358 C CG    . ASP B 2 132 ? 132.218 132.510 93.759  1.00 73.06  ? 132 ASP B CG    1 
ATOM   8359 O OD1   . ASP B 2 132 ? 132.405 132.318 94.973  1.00 73.97  ? 132 ASP B OD1   1 
ATOM   8360 O OD2   . ASP B 2 132 ? 132.906 133.314 93.098  1.00 73.17  ? 132 ASP B OD2   1 
ATOM   8361 N N     . PRO B 2 133 ? 129.549 129.225 95.304  1.00 63.49  ? 133 PRO B N     1 
ATOM   8362 C CA    . PRO B 2 133 ? 129.932 128.056 96.111  1.00 63.17  ? 133 PRO B CA    1 
ATOM   8363 C C     . PRO B 2 133 ? 130.719 127.022 95.337  1.00 63.30  ? 133 PRO B C     1 
ATOM   8364 O O     . PRO B 2 133 ? 131.463 126.246 95.948  1.00 66.21  ? 133 PRO B O     1 
ATOM   8365 C CB    . PRO B 2 133 ? 128.581 127.499 96.582  1.00 59.15  ? 133 PRO B CB    1 
ATOM   8366 C CG    . PRO B 2 133 ? 127.595 128.017 95.601  1.00 57.68  ? 133 PRO B CG    1 
ATOM   8367 C CD    . PRO B 2 133 ? 128.088 129.366 95.194  1.00 64.58  ? 133 PRO B CD    1 
ATOM   8368 N N     . GLU B 2 134 ? 130.576 126.983 94.011  1.00 57.87  ? 134 GLU B N     1 
ATOM   8369 C CA    . GLU B 2 134 ? 131.362 126.046 93.217  1.00 60.01  ? 134 GLU B CA    1 
ATOM   8370 C C     . GLU B 2 134 ? 132.849 126.381 93.263  1.00 55.98  ? 134 GLU B C     1 
ATOM   8371 O O     . GLU B 2 134 ? 133.686 125.478 93.397  1.00 57.41  ? 134 GLU B O     1 
ATOM   8372 C CB    . GLU B 2 134 ? 130.846 126.015 91.775  1.00 66.43  ? 134 GLU B CB    1 
ATOM   8373 C CG    . GLU B 2 134 ? 130.858 127.352 91.026  1.00 72.64  ? 134 GLU B CG    1 
ATOM   8374 C CD    . GLU B 2 134 ? 129.507 128.050 91.018  1.00 75.82  ? 134 GLU B CD    1 
ATOM   8375 O OE1   . GLU B 2 134 ? 129.007 128.397 92.108  1.00 76.29  ? 134 GLU B OE1   1 
ATOM   8376 O OE2   . GLU B 2 134 ? 128.943 128.249 89.920  1.00 76.07  ? 134 GLU B OE2   1 
ATOM   8377 N N     . LEU B 2 135 ? 133.198 127.667 93.214  1.00 55.95  ? 135 LEU B N     1 
ATOM   8378 C CA    . LEU B 2 135 ? 134.599 128.048 93.329  1.00 60.02  ? 135 LEU B CA    1 
ATOM   8379 C C     . LEU B 2 135 ? 135.105 127.869 94.753  1.00 65.34  ? 135 LEU B C     1 
ATOM   8380 O O     . LEU B 2 135 ? 136.276 127.522 94.950  1.00 69.87  ? 135 LEU B O     1 
ATOM   8381 C CB    . LEU B 2 135 ? 134.794 129.493 92.864  1.00 62.02  ? 135 LEU B CB    1 
ATOM   8382 C CG    . LEU B 2 135 ? 136.233 130.018 92.834  1.00 66.50  ? 135 LEU B CG    1 
ATOM   8383 C CD1   . LEU B 2 135 ? 137.115 129.107 92.004  1.00 60.37  ? 135 LEU B CD1   1 
ATOM   8384 C CD2   . LEU B 2 135 ? 136.284 131.442 92.297  1.00 68.96  ? 135 LEU B CD2   1 
ATOM   8385 N N     . PHE B 2 136 ? 134.240 128.082 95.748  1.00 64.43  ? 136 PHE B N     1 
ATOM   8386 C CA    . PHE B 2 136 ? 134.603 127.758 97.123  1.00 57.55  ? 136 PHE B CA    1 
ATOM   8387 C C     . PHE B 2 136 ? 134.955 126.285 97.252  1.00 56.52  ? 136 PHE B C     1 
ATOM   8388 O O     . PHE B 2 136 ? 135.968 125.929 97.861  1.00 60.27  ? 136 PHE B O     1 
ATOM   8389 C CB    . PHE B 2 136 ? 133.465 128.121 98.075  1.00 57.19  ? 136 PHE B CB    1 
ATOM   8390 C CG    . PHE B 2 136 ? 133.769 127.831 99.515  1.00 59.66  ? 136 PHE B CG    1 
ATOM   8391 C CD1   . PHE B 2 136 ? 134.500 128.728 100.276 1.00 65.09  ? 136 PHE B CD1   1 
ATOM   8392 C CD2   . PHE B 2 136 ? 133.321 126.666 100.112 1.00 60.42  ? 136 PHE B CD2   1 
ATOM   8393 C CE1   . PHE B 2 136 ? 134.780 128.465 101.602 1.00 61.93  ? 136 PHE B CE1   1 
ATOM   8394 C CE2   . PHE B 2 136 ? 133.597 126.398 101.435 1.00 64.94  ? 136 PHE B CE2   1 
ATOM   8395 C CZ    . PHE B 2 136 ? 134.328 127.297 102.181 1.00 61.16  ? 136 PHE B CZ    1 
ATOM   8396 N N     . ASP B 2 137 ? 134.120 125.411 96.689  1.00 57.56  ? 137 ASP B N     1 
ATOM   8397 C CA    . ASP B 2 137 ? 134.399 123.982 96.755  1.00 57.66  ? 137 ASP B CA    1 
ATOM   8398 C C     . ASP B 2 137 ? 135.691 123.640 96.030  1.00 52.44  ? 137 ASP B C     1 
ATOM   8399 O O     . ASP B 2 137 ? 136.501 122.854 96.532  1.00 58.03  ? 137 ASP B O     1 
ATOM   8400 C CB    . ASP B 2 137 ? 133.231 123.190 96.175  1.00 60.44  ? 137 ASP B CB    1 
ATOM   8401 C CG    . ASP B 2 137 ? 132.064 123.099 97.129  1.00 66.48  ? 137 ASP B CG    1 
ATOM   8402 O OD1   . ASP B 2 137 ? 132.218 123.508 98.299  1.00 68.60  ? 137 ASP B OD1   1 
ATOM   8403 O OD2   . ASP B 2 137 ? 130.994 122.614 96.709  1.00 72.11  ? 137 ASP B OD2   1 
ATOM   8404 N N     . GLN B 2 138 ? 135.916 124.243 94.862  1.00 48.51  ? 138 GLN B N     1 
ATOM   8405 C CA    . GLN B 2 138 ? 137.130 123.960 94.100  1.00 54.05  ? 138 GLN B CA    1 
ATOM   8406 C C     . GLN B 2 138 ? 138.380 124.359 94.878  1.00 52.92  ? 138 GLN B C     1 
ATOM   8407 O O     . GLN B 2 138 ? 139.320 123.564 95.020  1.00 54.98  ? 138 GLN B O     1 
ATOM   8408 C CB    . GLN B 2 138 ? 137.072 124.685 92.756  1.00 50.53  ? 138 GLN B CB    1 
ATOM   8409 C CG    . GLN B 2 138 ? 138.394 124.780 92.030  1.00 44.84  ? 138 GLN B CG    1 
ATOM   8410 C CD    . GLN B 2 138 ? 138.278 125.559 90.738  1.00 57.18  ? 138 GLN B CD    1 
ATOM   8411 O OE1   . GLN B 2 138 ? 137.233 126.136 90.442  1.00 60.81  ? 138 GLN B OE1   1 
ATOM   8412 N NE2   . GLN B 2 138 ? 139.349 125.578 89.955  1.00 60.24  ? 138 GLN B NE2   1 
ATOM   8413 N N     . MET B 2 139 ? 138.399 125.583 95.409  1.00 52.30  ? 139 MET B N     1 
ATOM   8414 C CA    . MET B 2 139 ? 139.568 126.051 96.146  1.00 54.66  ? 139 MET B CA    1 
ATOM   8415 C C     . MET B 2 139 ? 139.753 125.283 97.448  1.00 55.81  ? 139 MET B C     1 
ATOM   8416 O O     . MET B 2 139 ? 140.887 124.986 97.837  1.00 58.72  ? 139 MET B O     1 
ATOM   8417 C CB    . MET B 2 139 ? 139.454 127.551 96.414  1.00 61.07  ? 139 MET B CB    1 
ATOM   8418 C CG    . MET B 2 139 ? 139.648 128.410 95.173  1.00 63.84  ? 139 MET B CG    1 
ATOM   8419 S SD    . MET B 2 139 ? 139.358 130.161 95.479  1.00 70.22  ? 139 MET B SD    1 
ATOM   8420 C CE    . MET B 2 139 ? 139.851 130.872 93.911  1.00 56.23  ? 139 MET B CE    1 
ATOM   8421 N N     . ALA B 2 140 ? 138.658 124.952 98.140  1.00 53.40  ? 140 ALA B N     1 
ATOM   8422 C CA    . ALA B 2 140 ? 138.768 124.192 99.379  1.00 44.14  ? 140 ALA B CA    1 
ATOM   8423 C C     . ALA B 2 140 ? 139.322 122.797 99.129  1.00 48.19  ? 140 ALA B C     1 
ATOM   8424 O O     . ALA B 2 140 ? 140.182 122.322 99.879  1.00 57.41  ? 140 ALA B O     1 
ATOM   8425 C CB    . ALA B 2 140 ? 137.408 124.115 100.070 1.00 46.73  ? 140 ALA B CB    1 
ATOM   8426 N N     . GLN B 2 141 ? 138.842 122.120 98.082  1.00 48.94  ? 141 GLN B N     1 
ATOM   8427 C CA    . GLN B 2 141 ? 139.381 120.806 97.749  1.00 50.10  ? 141 GLN B CA    1 
ATOM   8428 C C     . GLN B 2 141 ? 140.852 120.896 97.372  1.00 53.34  ? 141 GLN B C     1 
ATOM   8429 O O     . GLN B 2 141 ? 141.665 120.080 97.825  1.00 56.85  ? 141 GLN B O     1 
ATOM   8430 C CB    . GLN B 2 141 ? 138.577 120.177 96.615  1.00 55.54  ? 141 GLN B CB    1 
ATOM   8431 C CG    . GLN B 2 141 ? 137.150 119.831 96.988  1.00 56.99  ? 141 GLN B CG    1 
ATOM   8432 C CD    . GLN B 2 141 ? 136.333 119.368 95.800  1.00 59.39  ? 141 GLN B CD    1 
ATOM   8433 O OE1   . GLN B 2 141 ? 136.233 118.174 95.530  1.00 65.18  ? 141 GLN B OE1   1 
ATOM   8434 N NE2   . GLN B 2 141 ? 135.743 120.314 95.083  1.00 53.27  ? 141 GLN B NE2   1 
ATOM   8435 N N     . GLU B 2 142 ? 141.217 121.896 96.564  1.00 54.63  ? 142 GLU B N     1 
ATOM   8436 C CA    . GLU B 2 142 ? 142.618 122.076 96.197  1.00 55.72  ? 142 GLU B CA    1 
ATOM   8437 C C     . GLU B 2 142 ? 143.485 122.301 97.429  1.00 56.23  ? 142 GLU B C     1 
ATOM   8438 O O     . GLU B 2 142 ? 144.564 121.713 97.559  1.00 60.34  ? 142 GLU B O     1 
ATOM   8439 C CB    . GLU B 2 142 ? 142.755 123.241 95.216  1.00 63.65  ? 142 GLU B CB    1 
ATOM   8440 C CG    . GLU B 2 142 ? 144.186 123.704 94.995  1.00 72.94  ? 142 GLU B CG    1 
ATOM   8441 C CD    . GLU B 2 142 ? 145.034 122.678 94.271  1.00 74.93  ? 142 GLU B CD    1 
ATOM   8442 O OE1   . GLU B 2 142 ? 144.465 121.783 93.611  1.00 78.39  ? 142 GLU B OE1   1 
ATOM   8443 O OE2   . GLU B 2 142 ? 146.275 122.771 94.360  1.00 74.67  ? 142 GLU B OE2   1 
ATOM   8444 N N     . PHE B 2 143 ? 143.022 123.146 98.354  1.00 52.34  ? 143 PHE B N     1 
ATOM   8445 C CA    . PHE B 2 143 ? 143.811 123.469 99.539  1.00 51.63  ? 143 PHE B CA    1 
ATOM   8446 C C     . PHE B 2 143 ? 143.929 122.274 100.478 1.00 59.54  ? 143 PHE B C     1 
ATOM   8447 O O     . PHE B 2 143 ? 145.005 122.026 101.036 1.00 67.51  ? 143 PHE B O     1 
ATOM   8448 C CB    . PHE B 2 143 ? 143.194 124.666 100.264 1.00 53.57  ? 143 PHE B CB    1 
ATOM   8449 C CG    . PHE B 2 143 ? 144.144 125.382 101.187 1.00 57.12  ? 143 PHE B CG    1 
ATOM   8450 C CD1   . PHE B 2 143 ? 144.302 124.972 102.500 1.00 59.08  ? 143 PHE B CD1   1 
ATOM   8451 C CD2   . PHE B 2 143 ? 144.868 126.478 100.743 1.00 58.61  ? 143 PHE B CD2   1 
ATOM   8452 C CE1   . PHE B 2 143 ? 145.168 125.634 103.350 1.00 59.29  ? 143 PHE B CE1   1 
ATOM   8453 C CE2   . PHE B 2 143 ? 145.736 127.144 101.587 1.00 60.14  ? 143 PHE B CE2   1 
ATOM   8454 C CZ    . PHE B 2 143 ? 145.885 126.721 102.892 1.00 62.19  ? 143 PHE B CZ    1 
ATOM   8455 N N     . THR B 2 144 ? 142.842 121.521 100.674 1.00 56.77  ? 144 THR B N     1 
ATOM   8456 C CA    . THR B 2 144 ? 142.911 120.370 101.571 1.00 55.00  ? 144 THR B CA    1 
ATOM   8457 C C     . THR B 2 144 ? 143.770 119.261 100.977 1.00 55.15  ? 144 THR B C     1 
ATOM   8458 O O     . THR B 2 144 ? 144.494 118.574 101.707 1.00 57.40  ? 144 THR B O     1 
ATOM   8459 C CB    . THR B 2 144 ? 141.510 119.845 101.899 1.00 47.89  ? 144 THR B CB    1 
ATOM   8460 O OG1   . THR B 2 144 ? 140.823 119.496 100.692 1.00 49.49  ? 144 THR B OG1   1 
ATOM   8461 C CG2   . THR B 2 144 ? 140.706 120.887 102.658 1.00 46.71  ? 144 THR B CG2   1 
ATOM   8462 N N     . LEU B 2 145 ? 143.709 119.069 99.656  1.00 53.08  ? 145 LEU B N     1 
ATOM   8463 C CA    . LEU B 2 145 ? 144.573 118.079 99.024  1.00 54.99  ? 145 LEU B CA    1 
ATOM   8464 C C     . LEU B 2 145 ? 146.031 118.516 99.035  1.00 61.42  ? 145 LEU B C     1 
ATOM   8465 O O     . LEU B 2 145 ? 146.928 117.673 99.149  1.00 62.44  ? 145 LEU B O     1 
ATOM   8466 C CB    . LEU B 2 145 ? 144.109 117.814 97.593  1.00 57.83  ? 145 LEU B CB    1 
ATOM   8467 C CG    . LEU B 2 145 ? 144.893 116.772 96.795  1.00 65.32  ? 145 LEU B CG    1 
ATOM   8468 C CD1   . LEU B 2 145 ? 144.811 115.411 97.466  1.00 70.43  ? 145 LEU B CD1   1 
ATOM   8469 C CD2   . LEU B 2 145 ? 144.382 116.700 95.364  1.00 63.68  ? 145 LEU B CD2   1 
ATOM   8470 N N     . GLN B 2 146 ? 146.290 119.822 98.915  1.00 66.11  ? 146 GLN B N     1 
ATOM   8471 C CA    . GLN B 2 146 ? 147.666 120.309 98.917  1.00 68.98  ? 146 GLN B CA    1 
ATOM   8472 C C     . GLN B 2 146 ? 148.359 120.007 100.239 1.00 69.80  ? 146 GLN B C     1 
ATOM   8473 O O     . GLN B 2 146 ? 149.515 119.569 100.256 1.00 76.99  ? 146 GLN B O     1 
ATOM   8474 C CB    . GLN B 2 146 ? 147.693 121.812 98.633  1.00 68.87  ? 146 GLN B CB    1 
ATOM   8475 C CG    . GLN B 2 146 ? 149.085 122.429 98.662  1.00 71.44  ? 146 GLN B CG    1 
ATOM   8476 C CD    . GLN B 2 146 ? 149.064 123.932 98.450  1.00 75.68  ? 146 GLN B CD    1 
ATOM   8477 O OE1   . GLN B 2 146 ? 148.006 124.561 98.484  1.00 74.58  ? 146 GLN B OE1   1 
ATOM   8478 N NE2   . GLN B 2 146 ? 150.237 124.515 98.227  1.00 74.59  ? 146 GLN B NE2   1 
ATOM   8479 N N     . PHE B 2 147 ? 147.669 120.228 101.356 1.00 66.22  ? 147 PHE B N     1 
ATOM   8480 C CA    . PHE B 2 147 ? 148.246 120.016 102.684 1.00 73.03  ? 147 PHE B CA    1 
ATOM   8481 C C     . PHE B 2 147 ? 147.194 119.325 103.544 1.00 74.13  ? 147 PHE B C     1 
ATOM   8482 O O     . PHE B 2 147 ? 146.269 119.972 104.044 1.00 79.58  ? 147 PHE B O     1 
ATOM   8483 C CB    . PHE B 2 147 ? 148.699 121.332 103.305 1.00 77.92  ? 147 PHE B CB    1 
ATOM   8484 C CG    . PHE B 2 147 ? 149.610 121.162 104.486 1.00 84.32  ? 147 PHE B CG    1 
ATOM   8485 C CD1   . PHE B 2 147 ? 149.095 121.070 105.769 1.00 80.14  ? 147 PHE B CD1   1 
ATOM   8486 C CD2   . PHE B 2 147 ? 150.982 121.093 104.314 1.00 83.47  ? 147 PHE B CD2   1 
ATOM   8487 C CE1   . PHE B 2 147 ? 149.932 120.913 106.857 1.00 78.33  ? 147 PHE B CE1   1 
ATOM   8488 C CE2   . PHE B 2 147 ? 151.824 120.937 105.397 1.00 81.41  ? 147 PHE B CE2   1 
ATOM   8489 C CZ    . PHE B 2 147 ? 151.299 120.846 106.671 1.00 81.78  ? 147 PHE B CZ    1 
ATOM   8490 N N     . GLY B 2 148 ? 147.338 118.014 103.711 1.00 71.05  ? 148 GLY B N     1 
ATOM   8491 C CA    . GLY B 2 148 ? 146.401 117.244 104.502 1.00 70.20  ? 148 GLY B CA    1 
ATOM   8492 C C     . GLY B 2 148 ? 146.952 115.895 104.910 1.00 74.92  ? 148 GLY B C     1 
ATOM   8493 O O     . GLY B 2 148 ? 147.675 115.255 104.141 1.00 77.62  ? 148 GLY B O     1 
ATOM   8494 N N     . VAL B 2 149 ? 146.616 115.452 106.121 1.00 74.53  ? 149 VAL B N     1 
ATOM   8495 C CA    . VAL B 2 149 ? 147.112 114.174 106.614 1.00 72.56  ? 149 VAL B CA    1 
ATOM   8496 C C     . VAL B 2 149 ? 146.371 113.041 105.921 1.00 75.34  ? 149 VAL B C     1 
ATOM   8497 O O     . VAL B 2 149 ? 145.166 113.135 105.649 1.00 75.55  ? 149 VAL B O     1 
ATOM   8498 C CB    . VAL B 2 149 ? 146.959 114.092 108.142 1.00 73.65  ? 149 VAL B CB    1 
ATOM   8499 C CG1   . VAL B 2 149 ? 147.627 112.840 108.681 1.00 77.85  ? 149 VAL B CG1   1 
ATOM   8500 C CG2   . VAL B 2 149 ? 147.537 115.335 108.800 1.00 74.37  ? 149 VAL B CG2   1 
ATOM   8501 N N     . ASP B 2 150 ? 147.094 111.963 105.621 1.00 79.08  ? 150 ASP B N     1 
ATOM   8502 C CA    . ASP B 2 150 ? 146.484 110.809 104.977 1.00 78.04  ? 150 ASP B CA    1 
ATOM   8503 C C     . ASP B 2 150 ? 145.421 110.195 105.877 1.00 80.20  ? 150 ASP B C     1 
ATOM   8504 O O     . ASP B 2 150 ? 145.559 110.171 107.104 1.00 84.61  ? 150 ASP B O     1 
ATOM   8505 C CB    . ASP B 2 150 ? 147.549 109.767 104.636 1.00 74.58  ? 150 ASP B CB    1 
ATOM   8506 C CG    . ASP B 2 150 ? 148.556 110.272 103.625 1.00 80.71  ? 150 ASP B CG    1 
ATOM   8507 O OD1   . ASP B 2 150 ? 148.190 111.132 102.796 1.00 86.20  ? 150 ASP B OD1   1 
ATOM   8508 O OD2   . ASP B 2 150 ? 149.715 109.808 103.656 1.00 84.57  ? 150 ASP B OD2   1 
ATOM   8509 N N     . ARG B 2 151 ? 144.357 109.703 105.262 1.00 75.28  ? 151 ARG B N     1 
ATOM   8510 C CA    . ARG B 2 151 ? 143.269 109.086 106.009 1.00 79.27  ? 151 ARG B CA    1 
ATOM   8511 C C     . ARG B 2 151 ? 143.760 107.807 106.676 1.00 87.78  ? 151 ARG B C     1 
ATOM   8512 O O     . ARG B 2 151 ? 144.256 106.910 105.982 1.00 90.22  ? 151 ARG B O     1 
ATOM   8513 C CB    . ARG B 2 151 ? 142.102 108.787 105.076 1.00 73.25  ? 151 ARG B CB    1 
ATOM   8514 C CG    . ARG B 2 151 ? 141.644 109.982 104.262 1.00 65.49  ? 151 ARG B CG    1 
ATOM   8515 C CD    . ARG B 2 151 ? 140.744 110.901 105.071 1.00 57.37  ? 151 ARG B CD    1 
ATOM   8516 N NE    . ARG B 2 151 ? 139.436 110.304 105.313 1.00 46.70  ? 151 ARG B NE    1 
ATOM   8517 C CZ    . ARG B 2 151 ? 138.410 110.947 105.849 1.00 44.08  ? 151 ARG B CZ    1 
ATOM   8518 N NH1   . ARG B 2 151 ? 138.504 112.213 106.217 1.00 44.02  ? 151 ARG B NH1   1 
ATOM   8519 N NH2   . ARG B 2 151 ? 137.258 110.306 106.017 1.00 47.69  ? 151 ARG B NH2   1 
ATOM   8520 N N     . PRO B 2 152 ? 143.645 107.674 108.005 1.00 90.76  ? 152 PRO B N     1 
ATOM   8521 C CA    . PRO B 2 152 ? 144.104 106.480 108.721 1.00 95.14  ? 152 PRO B CA    1 
ATOM   8522 C C     . PRO B 2 152 ? 143.159 105.293 108.554 1.00 100.18 ? 152 PRO B C     1 
ATOM   8523 O O     . PRO B 2 152 ? 141.949 105.499 108.464 1.00 102.03 ? 152 PRO B O     1 
ATOM   8524 C CB    . PRO B 2 152 ? 144.143 106.944 110.177 1.00 94.02  ? 152 PRO B CB    1 
ATOM   8525 C CG    . PRO B 2 152 ? 143.091 107.994 110.253 1.00 93.01  ? 152 PRO B CG    1 
ATOM   8526 C CD    . PRO B 2 152 ? 143.118 108.700 108.923 1.00 90.42  ? 152 PRO B CD    1 
ATOM   8527 N N     . SER C 3 80  ? 108.871 139.382 146.833 1.00 55.74  ? 80  SER C N     1 
ATOM   8528 C CA    . SER C 3 80  ? 109.501 140.496 146.134 1.00 59.11  ? 80  SER C CA    1 
ATOM   8529 C C     . SER C 3 80  ? 110.473 141.234 147.049 1.00 59.99  ? 80  SER C C     1 
ATOM   8530 O O     . SER C 3 80  ? 110.095 141.683 148.130 1.00 64.66  ? 80  SER C O     1 
ATOM   8531 C CB    . SER C 3 80  ? 108.441 141.459 145.604 1.00 57.51  ? 80  SER C CB    1 
ATOM   8532 O OG    . SER C 3 80  ? 107.671 141.992 146.665 1.00 57.43  ? 80  SER C OG    1 
ATOM   8533 N N     . ILE C 3 81  ? 111.729 141.357 146.615 1.00 57.04  ? 81  ILE C N     1 
ATOM   8534 C CA    . ILE C 3 81  ? 112.766 142.023 147.392 1.00 57.18  ? 81  ILE C CA    1 
ATOM   8535 C C     . ILE C 3 81  ? 113.522 142.989 146.491 1.00 60.50  ? 81  ILE C C     1 
ATOM   8536 O O     . ILE C 3 81  ? 113.350 143.005 145.272 1.00 59.80  ? 81  ILE C O     1 
ATOM   8537 C CB    . ILE C 3 81  ? 113.762 141.034 148.039 1.00 54.22  ? 81  ILE C CB    1 
ATOM   8538 C CG1   . ILE C 3 81  ? 114.637 140.386 146.967 1.00 53.72  ? 81  ILE C CG1   1 
ATOM   8539 C CG2   . ILE C 3 81  ? 113.027 139.987 148.863 1.00 60.73  ? 81  ILE C CG2   1 
ATOM   8540 C CD1   . ILE C 3 81  ? 115.660 139.425 147.517 1.00 61.08  ? 81  ILE C CD1   1 
ATOM   8541 N N     . LEU C 3 82  ? 114.344 143.826 147.116 1.00 60.38  ? 82  LEU C N     1 
ATOM   8542 C CA    . LEU C 3 82  ? 115.256 144.715 146.407 1.00 56.97  ? 82  LEU C CA    1 
ATOM   8543 C C     . LEU C 3 82  ? 116.668 144.154 146.490 1.00 52.23  ? 82  LEU C C     1 
ATOM   8544 O O     . LEU C 3 82  ? 117.080 143.668 147.545 1.00 56.80  ? 82  LEU C O     1 
ATOM   8545 C CB    . LEU C 3 82  ? 115.221 146.128 146.994 1.00 55.77  ? 82  LEU C CB    1 
ATOM   8546 C CG    . LEU C 3 82  ? 114.018 147.020 146.673 1.00 57.62  ? 82  LEU C CG    1 
ATOM   8547 C CD1   . LEU C 3 82  ? 113.716 146.994 145.183 1.00 61.07  ? 82  LEU C CD1   1 
ATOM   8548 C CD2   . LEU C 3 82  ? 112.782 146.647 147.484 1.00 58.05  ? 82  LEU C CD2   1 
ATOM   8549 N N     . VAL C 3 83  ? 117.391 144.185 145.376 1.00 49.05  ? 83  VAL C N     1 
ATOM   8550 C CA    . VAL C 3 83  ? 118.809 143.851 145.345 1.00 49.23  ? 83  VAL C CA    1 
ATOM   8551 C C     . VAL C 3 83  ? 119.571 145.100 144.923 1.00 57.54  ? 83  VAL C C     1 
ATOM   8552 O O     . VAL C 3 83  ? 119.326 145.648 143.842 1.00 62.30  ? 83  VAL C O     1 
ATOM   8553 C CB    . VAL C 3 83  ? 119.096 142.675 144.402 1.00 52.01  ? 83  VAL C CB    1 
ATOM   8554 C CG1   . VAL C 3 83  ? 120.587 142.390 144.343 1.00 53.03  ? 83  VAL C CG1   1 
ATOM   8555 C CG2   . VAL C 3 83  ? 118.332 141.438 144.854 1.00 55.10  ? 83  VAL C CG2   1 
ATOM   8556 N N     . ARG C 3 84  ? 120.472 145.567 145.782 1.00 56.46  ? 84  ARG C N     1 
ATOM   8557 C CA    . ARG C 3 84  ? 121.320 146.706 145.452 1.00 57.50  ? 84  ARG C CA    1 
ATOM   8558 C C     . ARG C 3 84  ? 122.559 146.209 144.717 1.00 58.18  ? 84  ARG C C     1 
ATOM   8559 O O     . ARG C 3 84  ? 123.375 145.477 145.293 1.00 60.47  ? 84  ARG C O     1 
ATOM   8560 C CB    . ARG C 3 84  ? 121.707 147.476 146.711 1.00 58.79  ? 84  ARG C CB    1 
ATOM   8561 C CG    . ARG C 3 84  ? 122.492 148.748 146.434 1.00 63.84  ? 84  ARG C CG    1 
ATOM   8562 C CD    . ARG C 3 84  ? 122.833 149.490 147.718 1.00 64.24  ? 84  ARG C CD    1 
ATOM   8563 N NE    . ARG C 3 84  ? 121.644 149.977 148.408 1.00 68.54  ? 84  ARG C NE    1 
ATOM   8564 C CZ    . ARG C 3 84  ? 121.663 150.714 149.510 1.00 67.06  ? 84  ARG C CZ    1 
ATOM   8565 N NH1   . ARG C 3 84  ? 122.800 151.072 150.085 1.00 65.83  ? 84  ARG C NH1   1 
ATOM   8566 N NH2   . ARG C 3 84  ? 120.511 151.105 150.049 1.00 65.68  ? 84  ARG C NH2   1 
ATOM   8567 N N     . ASN C 3 85  ? 122.698 146.607 143.453 1.00 58.98  ? 85  ASN C N     1 
ATOM   8568 C CA    . ASN C 3 85  ? 123.784 146.132 142.611 1.00 64.21  ? 85  ASN C CA    1 
ATOM   8569 C C     . ASN C 3 85  ? 125.071 146.908 142.883 1.00 69.56  ? 85  ASN C C     1 
ATOM   8570 O O     . ASN C 3 85  ? 125.142 147.773 143.761 1.00 71.26  ? 85  ASN C O     1 
ATOM   8571 C CB    . ASN C 3 85  ? 123.408 146.218 141.129 1.00 66.34  ? 85  ASN C CB    1 
ATOM   8572 C CG    . ASN C 3 85  ? 123.032 147.621 140.689 1.00 71.26  ? 85  ASN C CG    1 
ATOM   8573 O OD1   . ASN C 3 85  ? 123.327 148.602 141.365 1.00 72.72  ? 85  ASN C OD1   1 
ATOM   8574 N ND2   . ASN C 3 85  ? 122.379 147.721 139.539 1.00 72.71  ? 85  ASN C ND2   1 
ATOM   8575 N N     . ASP C 3 86  ? 126.111 146.565 142.118 1.00 72.85  ? 86  ASP C N     1 
ATOM   8576 C CA    . ASP C 3 86  ? 127.394 147.248 142.255 1.00 76.72  ? 86  ASP C CA    1 
ATOM   8577 C C     . ASP C 3 86  ? 127.277 148.733 141.930 1.00 75.53  ? 86  ASP C C     1 
ATOM   8578 O O     . ASP C 3 86  ? 127.919 149.569 142.576 1.00 68.85  ? 86  ASP C O     1 
ATOM   8579 C CB    . ASP C 3 86  ? 128.458 146.573 141.380 1.00 76.66  ? 86  ASP C CB    1 
ATOM   8580 C CG    . ASP C 3 86  ? 128.067 146.482 139.905 1.00 80.39  ? 86  ASP C CG    1 
ATOM   8581 O OD1   . ASP C 3 86  ? 126.901 146.738 139.543 1.00 77.66  ? 86  ASP C OD1   1 
ATOM   8582 O OD2   . ASP C 3 86  ? 128.953 146.138 139.093 1.00 81.34  ? 86  ASP C OD2   1 
ATOM   8583 N N     . LYS C 3 87  ? 126.452 149.084 140.946 1.00 76.69  ? 87  LYS C N     1 
ATOM   8584 C CA    . LYS C 3 87  ? 126.314 150.466 140.507 1.00 75.28  ? 87  LYS C CA    1 
ATOM   8585 C C     . LYS C 3 87  ? 125.382 151.295 141.395 1.00 71.70  ? 87  LYS C C     1 
ATOM   8586 O O     . LYS C 3 87  ? 125.000 152.402 141.000 1.00 74.17  ? 87  LYS C O     1 
ATOM   8587 C CB    . LYS C 3 87  ? 125.830 150.501 139.053 1.00 76.98  ? 87  LYS C CB    1 
ATOM   8588 C CG    . LYS C 3 87  ? 126.904 150.147 138.031 1.00 78.65  ? 87  LYS C CG    1 
ATOM   8589 C CD    . LYS C 3 87  ? 126.321 150.019 136.629 1.00 82.90  ? 87  LYS C CD    1 
ATOM   8590 C CE    . LYS C 3 87  ? 125.511 148.737 136.472 1.00 83.78  ? 87  LYS C CE    1 
ATOM   8591 N NZ    . LYS C 3 87  ? 126.344 147.518 136.668 1.00 81.02  ? 87  LYS C NZ    1 
ATOM   8592 N N     . GLY C 3 88  ? 125.014 150.796 142.575 1.00 66.74  ? 88  GLY C N     1 
ATOM   8593 C CA    . GLY C 3 88  ? 124.256 151.575 143.535 1.00 66.64  ? 88  GLY C CA    1 
ATOM   8594 C C     . GLY C 3 88  ? 122.765 151.658 143.301 1.00 66.62  ? 88  GLY C C     1 
ATOM   8595 O O     . GLY C 3 88  ? 122.084 152.396 144.023 1.00 65.62  ? 88  GLY C O     1 
ATOM   8596 N N     . ARG C 3 89  ? 122.233 150.929 142.324 1.00 67.02  ? 89  ARG C N     1 
ATOM   8597 C CA    . ARG C 3 89  ? 120.813 150.961 141.994 1.00 69.21  ? 89  ARG C CA    1 
ATOM   8598 C C     . ARG C 3 89  ? 120.113 149.743 142.587 1.00 69.31  ? 89  ARG C C     1 
ATOM   8599 O O     . ARG C 3 89  ? 120.555 148.607 142.383 1.00 69.51  ? 89  ARG C O     1 
ATOM   8600 C CB    . ARG C 3 89  ? 120.611 151.010 140.480 1.00 71.81  ? 89  ARG C CB    1 
ATOM   8601 C CG    . ARG C 3 89  ? 119.153 150.996 140.050 1.00 71.93  ? 89  ARG C CG    1 
ATOM   8602 C CD    . ARG C 3 89  ? 118.798 149.723 139.283 1.00 68.80  ? 89  ARG C CD    1 
ATOM   8603 N NE    . ARG C 3 89  ? 117.385 149.694 138.923 1.00 69.59  ? 89  ARG C NE    1 
ATOM   8604 C CZ    . ARG C 3 89  ? 116.801 148.744 138.203 1.00 69.24  ? 89  ARG C CZ    1 
ATOM   8605 N NH1   . ARG C 3 89  ? 117.483 147.716 137.724 1.00 65.51  ? 89  ARG C NH1   1 
ATOM   8606 N NH2   . ARG C 3 89  ? 115.496 148.828 137.956 1.00 70.78  ? 89  ARG C NH2   1 
ATOM   8607 N N     . SER C 3 90  ? 119.028 149.983 143.321 1.00 67.81  ? 90  SER C N     1 
ATOM   8608 C CA    . SER C 3 90  ? 118.212 148.912 143.888 1.00 65.79  ? 90  SER C CA    1 
ATOM   8609 C C     . SER C 3 90  ? 117.210 148.434 142.841 1.00 66.07  ? 90  SER C C     1 
ATOM   8610 O O     . SER C 3 90  ? 116.356 149.205 142.389 1.00 68.00  ? 90  SER C O     1 
ATOM   8611 C CB    . SER C 3 90  ? 117.503 149.394 145.150 1.00 68.00  ? 90  SER C CB    1 
ATOM   8612 O OG    . SER C 3 90  ? 118.425 149.896 146.104 1.00 67.39  ? 90  SER C OG    1 
ATOM   8613 N N     . SER C 3 91  ? 117.313 147.164 142.452 1.00 62.32  ? 91  SER C N     1 
ATOM   8614 C CA    . SER C 3 91  ? 116.440 146.554 141.463 1.00 59.08  ? 91  SER C CA    1 
ATOM   8615 C C     . SER C 3 91  ? 115.485 145.574 142.124 1.00 57.33  ? 91  SER C C     1 
ATOM   8616 O O     . SER C 3 91  ? 115.915 144.774 142.964 1.00 59.10  ? 91  SER C O     1 
ATOM   8617 C CB    . SER C 3 91  ? 117.266 145.827 140.400 1.00 60.87  ? 91  SER C CB    1 
ATOM   8618 O OG    . SER C 3 91  ? 116.422 145.156 139.483 1.00 64.28  ? 91  SER C OG    1 
ATOM   8619 N N     . PRO C 3 92  ? 114.197 145.605 141.788 1.00 55.88  ? 92  PRO C N     1 
ATOM   8620 C CA    . PRO C 3 92  ? 113.263 144.631 142.364 1.00 58.72  ? 92  PRO C CA    1 
ATOM   8621 C C     . PRO C 3 92  ? 113.378 143.265 141.702 1.00 61.69  ? 92  PRO C C     1 
ATOM   8622 O O     . PRO C 3 92  ? 113.624 143.151 140.499 1.00 63.11  ? 92  PRO C O     1 
ATOM   8623 C CB    . PRO C 3 92  ? 111.893 145.264 142.101 1.00 56.39  ? 92  PRO C CB    1 
ATOM   8624 C CG    . PRO C 3 92  ? 112.104 146.066 140.862 1.00 56.26  ? 92  PRO C CG    1 
ATOM   8625 C CD    . PRO C 3 92  ? 113.508 146.605 140.954 1.00 56.17  ? 92  PRO C CD    1 
ATOM   8626 N N     . TYR C 3 93  ? 113.198 142.225 142.513 1.00 57.71  ? 93  TYR C N     1 
ATOM   8627 C CA    . TYR C 3 93  ? 113.161 140.845 142.057 1.00 55.58  ? 93  TYR C CA    1 
ATOM   8628 C C     . TYR C 3 93  ? 111.994 140.144 142.730 1.00 59.84  ? 93  TYR C C     1 
ATOM   8629 O O     . TYR C 3 93  ? 111.586 140.511 143.835 1.00 62.93  ? 93  TYR C O     1 
ATOM   8630 C CB    . TYR C 3 93  ? 114.452 140.085 142.382 1.00 54.40  ? 93  TYR C CB    1 
ATOM   8631 C CG    . TYR C 3 93  ? 115.680 140.562 141.651 1.00 53.98  ? 93  TYR C CG    1 
ATOM   8632 C CD1   . TYR C 3 93  ? 116.294 141.757 141.990 1.00 57.46  ? 93  TYR C CD1   1 
ATOM   8633 C CD2   . TYR C 3 93  ? 116.247 139.800 140.642 1.00 54.60  ? 93  TYR C CD2   1 
ATOM   8634 C CE1   . TYR C 3 93  ? 117.423 142.193 141.329 1.00 58.16  ? 93  TYR C CE1   1 
ATOM   8635 C CE2   . TYR C 3 93  ? 117.379 140.224 139.977 1.00 58.60  ? 93  TYR C CE2   1 
ATOM   8636 C CZ    . TYR C 3 93  ? 117.963 141.422 140.325 1.00 60.47  ? 93  TYR C CZ    1 
ATOM   8637 O OH    . TYR C 3 93  ? 119.091 141.852 139.665 1.00 62.57  ? 93  TYR C OH    1 
ATOM   8638 N N     . GLU C 3 94  ? 111.462 139.130 142.057 1.00 59.24  ? 94  GLU C N     1 
ATOM   8639 C CA    . GLU C 3 94  ? 110.390 138.301 142.590 1.00 62.45  ? 94  GLU C CA    1 
ATOM   8640 C C     . GLU C 3 94  ? 110.965 136.932 142.927 1.00 67.24  ? 94  GLU C C     1 
ATOM   8641 O O     . GLU C 3 94  ? 111.562 136.278 142.066 1.00 67.11  ? 94  GLU C O     1 
ATOM   8642 C CB    . GLU C 3 94  ? 109.243 138.183 141.586 1.00 63.82  ? 94  GLU C CB    1 
ATOM   8643 C CG    . GLU C 3 94  ? 108.093 137.290 142.027 1.00 67.57  ? 94  GLU C CG    1 
ATOM   8644 C CD    . GLU C 3 94  ? 107.116 137.989 142.956 1.00 66.72  ? 94  GLU C CD    1 
ATOM   8645 O OE1   . GLU C 3 94  ? 107.558 138.759 143.835 1.00 65.41  ? 94  GLU C OE1   1 
ATOM   8646 O OE2   . GLU C 3 94  ? 105.897 137.768 142.804 1.00 67.85  ? 94  GLU C OE2   1 
ATOM   8647 N N     . VAL C 3 95  ? 110.787 136.504 144.177 1.00 70.17  ? 95  VAL C N     1 
ATOM   8648 C CA    . VAL C 3 95  ? 111.363 135.255 144.659 1.00 73.69  ? 95  VAL C CA    1 
ATOM   8649 C C     . VAL C 3 95  ? 110.518 134.752 145.822 1.00 75.68  ? 95  VAL C C     1 
ATOM   8650 O O     . VAL C 3 95  ? 109.849 135.529 146.509 1.00 76.21  ? 95  VAL C O     1 
ATOM   8651 C CB    . VAL C 3 95  ? 112.846 135.447 145.063 1.00 71.51  ? 95  VAL C CB    1 
ATOM   8652 C CG1   . VAL C 3 95  ? 112.956 136.280 146.329 1.00 70.28  ? 95  VAL C CG1   1 
ATOM   8653 C CG2   . VAL C 3 95  ? 113.551 134.107 145.215 1.00 74.16  ? 95  VAL C CG2   1 
ATOM   8654 N N     . GLN C 3 96  ? 110.545 133.439 146.034 1.00 80.03  ? 96  GLN C N     1 
ATOM   8655 C CA    . GLN C 3 96  ? 109.765 132.781 147.071 1.00 85.61  ? 96  GLN C CA    1 
ATOM   8656 C C     . GLN C 3 96  ? 110.629 132.469 148.289 1.00 85.55  ? 96  GLN C C     1 
ATOM   8657 O O     . GLN C 3 96  ? 111.861 132.457 148.222 1.00 83.90  ? 96  GLN C O     1 
ATOM   8658 C CB    . GLN C 3 96  ? 109.136 131.491 146.535 1.00 87.87  ? 96  GLN C CB    1 
ATOM   8659 C CG    . GLN C 3 96  ? 108.228 131.695 145.336 1.00 87.59  ? 96  GLN C CG    1 
ATOM   8660 C CD    . GLN C 3 96  ? 106.975 132.475 145.680 1.00 89.73  ? 96  GLN C CD    1 
ATOM   8661 O OE1   . GLN C 3 96  ? 106.549 132.512 146.834 1.00 91.78  ? 96  GLN C OE1   1 
ATOM   8662 N NE2   . GLN C 3 96  ? 106.377 133.107 144.676 1.00 87.22  ? 96  GLN C NE2   1 
ATOM   8663 N N     . LEU C 3 97  ? 109.957 132.219 149.416 1.00 86.99  ? 97  LEU C N     1 
ATOM   8664 C CA    . LEU C 3 97  ? 110.670 131.884 150.645 1.00 86.72  ? 97  LEU C CA    1 
ATOM   8665 C C     . LEU C 3 97  ? 111.409 130.558 150.516 1.00 87.62  ? 97  LEU C C     1 
ATOM   8666 O O     . LEU C 3 97  ? 112.568 130.442 150.933 1.00 86.86  ? 97  LEU C O     1 
ATOM   8667 C CB    . LEU C 3 97  ? 109.699 131.840 151.826 1.00 89.77  ? 97  LEU C CB    1 
ATOM   8668 C CG    . LEU C 3 97  ? 109.402 133.158 152.550 1.00 90.62  ? 97  LEU C CG    1 
ATOM   8669 C CD1   . LEU C 3 97  ? 110.695 133.817 153.012 1.00 85.35  ? 97  LEU C CD1   1 
ATOM   8670 C CD2   . LEU C 3 97  ? 108.588 134.108 151.682 1.00 88.46  ? 97  LEU C CD2   1 
ATOM   8671 N N     . LYS C 3 98  ? 110.758 129.545 149.943 1.00 88.27  ? 98  LYS C N     1 
ATOM   8672 C CA    . LYS C 3 98  ? 111.399 128.251 149.754 1.00 87.52  ? 98  LYS C CA    1 
ATOM   8673 C C     . LYS C 3 98  ? 112.404 128.252 148.612 1.00 82.92  ? 98  LYS C C     1 
ATOM   8674 O O     . LYS C 3 98  ? 113.181 127.299 148.493 1.00 80.57  ? 98  LYS C O     1 
ATOM   8675 C CB    . LYS C 3 98  ? 110.347 127.167 149.510 1.00 90.83  ? 98  LYS C CB    1 
ATOM   8676 C CG    . LYS C 3 98  ? 109.491 127.391 148.275 1.00 93.17  ? 98  LYS C CG    1 
ATOM   8677 C CD    . LYS C 3 98  ? 108.531 126.232 148.059 1.00 96.28  ? 98  LYS C CD    1 
ATOM   8678 C CE    . LYS C 3 98  ? 107.639 126.467 146.852 1.00 95.08  ? 98  LYS C CE    1 
ATOM   8679 N NZ    . LYS C 3 98  ? 106.778 127.670 147.024 1.00 93.45  ? 98  LYS C NZ    1 
ATOM   8680 N N     . GLN C 3 99  ? 112.403 129.286 147.776 1.00 79.81  ? 99  GLN C N     1 
ATOM   8681 C CA    . GLN C 3 99  ? 113.366 129.371 146.690 1.00 76.40  ? 99  GLN C CA    1 
ATOM   8682 C C     . GLN C 3 99  ? 114.770 129.559 147.248 1.00 75.62  ? 99  GLN C C     1 
ATOM   8683 O O     . GLN C 3 99  ? 114.979 130.299 148.213 1.00 79.12  ? 99  GLN C O     1 
ATOM   8684 C CB    . GLN C 3 99  ? 113.002 130.522 145.754 1.00 76.29  ? 99  GLN C CB    1 
ATOM   8685 C CG    . GLN C 3 99  ? 113.656 130.446 144.390 1.00 78.50  ? 99  GLN C CG    1 
ATOM   8686 C CD    . GLN C 3 99  ? 112.861 131.177 143.328 1.00 81.63  ? 99  GLN C CD    1 
ATOM   8687 O OE1   . GLN C 3 99  ? 111.845 131.807 143.622 1.00 81.33  ? 99  GLN C OE1   1 
ATOM   8688 N NE2   . GLN C 3 99  ? 113.316 131.091 142.083 1.00 83.87  ? 99  GLN C NE2   1 
ATOM   8689 N N     . THR C 3 100 ? 115.736 128.879 146.640 1.00 73.12  ? 100 THR C N     1 
ATOM   8690 C CA    . THR C 3 100 ? 117.094 128.908 147.152 1.00 73.69  ? 100 THR C CA    1 
ATOM   8691 C C     . THR C 3 100 ? 117.808 130.183 146.717 1.00 76.00  ? 100 THR C C     1 
ATOM   8692 O O     . THR C 3 100 ? 117.379 130.890 145.801 1.00 76.80  ? 100 THR C O     1 
ATOM   8693 C CB    . THR C 3 100 ? 117.883 127.688 146.677 1.00 72.40  ? 100 THR C CB    1 
ATOM   8694 O OG1   . THR C 3 100 ? 118.220 127.846 145.294 1.00 72.41  ? 100 THR C OG1   1 
ATOM   8695 C CG2   . THR C 3 100 ? 117.060 126.424 146.851 1.00 73.94  ? 100 THR C CG2   1 
ATOM   8696 N N     . VAL C 3 101 ? 118.916 130.474 147.402 1.00 74.30  ? 101 VAL C N     1 
ATOM   8697 C CA    . VAL C 3 101 ? 119.722 131.639 147.063 1.00 70.45  ? 101 VAL C CA    1 
ATOM   8698 C C     . VAL C 3 101 ? 120.357 131.498 145.684 1.00 70.73  ? 101 VAL C C     1 
ATOM   8699 O O     . VAL C 3 101 ? 120.693 132.507 145.056 1.00 71.68  ? 101 VAL C O     1 
ATOM   8700 C CB    . VAL C 3 101 ? 120.783 131.874 148.157 1.00 69.84  ? 101 VAL C CB    1 
ATOM   8701 C CG1   . VAL C 3 101 ? 121.576 133.147 147.891 1.00 72.69  ? 101 VAL C CG1   1 
ATOM   8702 C CG2   . VAL C 3 101 ? 120.120 131.949 149.521 1.00 70.36  ? 101 VAL C CG2   1 
ATOM   8703 N N     . ALA C 3 102 ? 120.521 130.269 145.187 1.00 69.30  ? 102 ALA C N     1 
ATOM   8704 C CA    . ALA C 3 102 ? 121.110 130.079 143.864 1.00 68.02  ? 102 ALA C CA    1 
ATOM   8705 C C     . ALA C 3 102 ? 120.240 130.691 142.769 1.00 70.55  ? 102 ALA C C     1 
ATOM   8706 O O     . ALA C 3 102 ? 120.753 131.342 141.850 1.00 69.11  ? 102 ALA C O     1 
ATOM   8707 C CB    . ALA C 3 102 ? 121.336 128.592 143.601 1.00 68.38  ? 102 ALA C CB    1 
ATOM   8708 N N     . GLU C 3 103 ? 118.921 130.488 142.844 1.00 71.04  ? 103 GLU C N     1 
ATOM   8709 C CA    . GLU C 3 103 ? 118.030 131.063 141.838 1.00 69.61  ? 103 GLU C CA    1 
ATOM   8710 C C     . GLU C 3 103 ? 118.040 132.586 141.892 1.00 66.04  ? 103 GLU C C     1 
ATOM   8711 O O     . GLU C 3 103 ? 118.066 133.250 140.848 1.00 65.11  ? 103 GLU C O     1 
ATOM   8712 C CB    . GLU C 3 103 ? 116.609 130.529 142.017 1.00 72.81  ? 103 GLU C CB    1 
ATOM   8713 C CG    . GLU C 3 103 ? 116.377 129.160 141.395 1.00 75.00  ? 103 GLU C CG    1 
ATOM   8714 C CD    . GLU C 3 103 ? 116.505 128.031 142.396 1.00 75.96  ? 103 GLU C CD    1 
ATOM   8715 O OE1   . GLU C 3 103 ? 116.088 128.219 143.557 1.00 77.18  ? 103 GLU C OE1   1 
ATOM   8716 O OE2   . GLU C 3 103 ? 117.020 126.957 142.022 1.00 74.92  ? 103 GLU C OE2   1 
ATOM   8717 N N     . LEU C 3 104 ? 118.011 133.157 143.098 1.00 63.21  ? 104 LEU C N     1 
ATOM   8718 C CA    . LEU C 3 104 ? 118.090 134.608 143.231 1.00 61.04  ? 104 LEU C CA    1 
ATOM   8719 C C     . LEU C 3 104 ? 119.403 135.137 142.670 1.00 60.01  ? 104 LEU C C     1 
ATOM   8720 O O     . LEU C 3 104 ? 119.427 136.168 141.985 1.00 64.46  ? 104 LEU C O     1 
ATOM   8721 C CB    . LEU C 3 104 ? 117.929 135.006 144.698 1.00 63.91  ? 104 LEU C CB    1 
ATOM   8722 C CG    . LEU C 3 104 ? 118.020 136.496 145.029 1.00 60.74  ? 104 LEU C CG    1 
ATOM   8723 C CD1   . LEU C 3 104 ? 116.901 137.267 144.348 1.00 57.95  ? 104 LEU C CD1   1 
ATOM   8724 C CD2   . LEU C 3 104 ? 117.984 136.714 146.536 1.00 59.53  ? 104 LEU C CD2   1 
ATOM   8725 N N     . LYS C 3 105 ? 120.505 134.436 142.939 1.00 57.79  ? 105 LYS C N     1 
ATOM   8726 C CA    . LYS C 3 105 ? 121.797 134.859 142.414 1.00 59.33  ? 105 LYS C CA    1 
ATOM   8727 C C     . LYS C 3 105 ? 121.818 134.816 140.893 1.00 63.05  ? 105 LYS C C     1 
ATOM   8728 O O     . LYS C 3 105 ? 122.330 135.737 140.254 1.00 65.70  ? 105 LYS C O     1 
ATOM   8729 C CB    . LYS C 3 105 ? 122.914 133.992 142.990 1.00 65.73  ? 105 LYS C CB    1 
ATOM   8730 C CG    . LYS C 3 105 ? 124.232 134.127 142.246 1.00 67.18  ? 105 LYS C CG    1 
ATOM   8731 C CD    . LYS C 3 105 ? 125.374 133.455 142.989 1.00 65.98  ? 105 LYS C CD    1 
ATOM   8732 C CE    . LYS C 3 105 ? 125.749 134.230 144.240 1.00 63.03  ? 105 LYS C CE    1 
ATOM   8733 N NZ    . LYS C 3 105 ? 126.983 133.688 144.875 1.00 66.36  ? 105 LYS C NZ    1 
ATOM   8734 N N     . GLN C 3 106 ? 121.263 133.761 140.291 1.00 63.10  ? 106 GLN C N     1 
ATOM   8735 C CA    . GLN C 3 106 ? 121.258 133.679 138.832 1.00 60.90  ? 106 GLN C CA    1 
ATOM   8736 C C     . GLN C 3 106 ? 120.351 134.740 138.218 1.00 59.46  ? 106 GLN C C     1 
ATOM   8737 O O     . GLN C 3 106 ? 120.651 135.279 137.144 1.00 61.21  ? 106 GLN C O     1 
ATOM   8738 C CB    . GLN C 3 106 ? 120.841 132.281 138.381 1.00 64.49  ? 106 GLN C CB    1 
ATOM   8739 C CG    . GLN C 3 106 ? 121.069 132.013 136.897 1.00 64.95  ? 106 GLN C CG    1 
ATOM   8740 C CD    . GLN C 3 106 ? 122.540 132.012 136.510 1.00 66.52  ? 106 GLN C CD    1 
ATOM   8741 O OE1   . GLN C 3 106 ? 123.419 131.842 137.356 1.00 71.21  ? 106 GLN C OE1   1 
ATOM   8742 N NE2   . GLN C 3 106 ? 122.813 132.203 135.224 1.00 58.05  ? 106 GLN C NE2   1 
ATOM   8743 N N     . GLN C 3 107 ? 119.231 135.046 138.879 1.00 57.71  ? 107 GLN C N     1 
ATOM   8744 C CA    . GLN C 3 107 ? 118.390 136.150 138.426 1.00 58.09  ? 107 GLN C CA    1 
ATOM   8745 C C     . GLN C 3 107 ? 119.157 137.465 138.461 1.00 59.18  ? 107 GLN C C     1 
ATOM   8746 O O     . GLN C 3 107 ? 119.083 138.264 137.518 1.00 61.61  ? 107 GLN C O     1 
ATOM   8747 C CB    . GLN C 3 107 ? 117.131 136.242 139.289 1.00 54.98  ? 107 GLN C CB    1 
ATOM   8748 C CG    . GLN C 3 107 ? 116.153 135.094 139.103 1.00 56.42  ? 107 GLN C CG    1 
ATOM   8749 C CD    . GLN C 3 107 ? 114.899 135.254 139.942 1.00 58.02  ? 107 GLN C CD    1 
ATOM   8750 O OE1   . GLN C 3 107 ? 114.690 136.287 140.576 1.00 58.87  ? 107 GLN C OE1   1 
ATOM   8751 N NE2   . GLN C 3 107 ? 114.055 134.229 139.947 1.00 61.70  ? 107 GLN C NE2   1 
ATOM   8752 N N     . VAL C 3 108 ? 119.907 137.702 139.539 1.00 58.13  ? 108 VAL C N     1 
ATOM   8753 C CA    . VAL C 3 108 ? 120.743 138.897 139.615 1.00 57.30  ? 108 VAL C CA    1 
ATOM   8754 C C     . VAL C 3 108 ? 121.796 138.882 138.513 1.00 57.94  ? 108 VAL C C     1 
ATOM   8755 O O     . VAL C 3 108 ? 122.121 139.922 137.931 1.00 61.55  ? 108 VAL C O     1 
ATOM   8756 C CB    . VAL C 3 108 ? 121.380 139.012 141.012 1.00 58.62  ? 108 VAL C CB    1 
ATOM   8757 C CG1   . VAL C 3 108 ? 122.415 140.125 141.040 1.00 59.87  ? 108 VAL C CG1   1 
ATOM   8758 C CG2   . VAL C 3 108 ? 120.307 139.256 142.060 1.00 57.16  ? 108 VAL C CG2   1 
ATOM   8759 N N     . CYS C 3 109 ? 122.336 137.703 138.204 1.00 54.89  ? 109 CYS C N     1 
ATOM   8760 C CA    . CYS C 3 109 ? 123.349 137.598 137.159 1.00 58.57  ? 109 CYS C CA    1 
ATOM   8761 C C     . CYS C 3 109 ? 122.784 138.000 135.805 1.00 63.59  ? 109 CYS C C     1 
ATOM   8762 O O     . CYS C 3 109 ? 123.411 138.760 135.059 1.00 65.06  ? 109 CYS C O     1 
ATOM   8763 C CB    . CYS C 3 109 ? 123.898 136.174 137.093 1.00 60.43  ? 109 CYS C CB    1 
ATOM   8764 S SG    . CYS C 3 109 ? 124.815 135.638 138.538 1.00 71.30  ? 109 CYS C SG    1 
ATOM   8765 N N     . GLN C 3 110 ? 121.601 137.488 135.468 1.00 63.33  ? 110 GLN C N     1 
ATOM   8766 C CA    . GLN C 3 110 ? 121.029 137.786 134.160 1.00 58.32  ? 110 GLN C CA    1 
ATOM   8767 C C     . GLN C 3 110 ? 120.511 139.217 134.080 1.00 58.75  ? 110 GLN C C     1 
ATOM   8768 O O     . GLN C 3 110 ? 120.545 139.823 133.003 1.00 60.74  ? 110 GLN C O     1 
ATOM   8769 C CB    . GLN C 3 110 ? 119.915 136.795 133.821 1.00 59.49  ? 110 GLN C CB    1 
ATOM   8770 C CG    . GLN C 3 110 ? 118.705 136.862 134.731 1.00 60.65  ? 110 GLN C CG    1 
ATOM   8771 C CD    . GLN C 3 110 ? 117.473 136.247 134.101 1.00 64.48  ? 110 GLN C CD    1 
ATOM   8772 O OE1   . GLN C 3 110 ? 117.073 136.622 132.999 1.00 65.45  ? 110 GLN C OE1   1 
ATOM   8773 N NE2   . GLN C 3 110 ? 116.865 135.295 134.798 1.00 63.71  ? 110 GLN C NE2   1 
ATOM   8774 N N     . LYS C 3 111 ? 120.037 139.779 135.194 1.00 58.13  ? 111 LYS C N     1 
ATOM   8775 C CA    . LYS C 3 111 ? 119.479 141.125 135.151 1.00 57.33  ? 111 LYS C CA    1 
ATOM   8776 C C     . LYS C 3 111 ? 120.556 142.202 135.213 1.00 59.69  ? 111 LYS C C     1 
ATOM   8777 O O     . LYS C 3 111 ? 120.474 143.201 134.489 1.00 61.47  ? 111 LYS C O     1 
ATOM   8778 C CB    . LYS C 3 111 ? 118.477 141.313 136.292 1.00 56.60  ? 111 LYS C CB    1 
ATOM   8779 C CG    . LYS C 3 111 ? 117.699 142.618 136.235 1.00 61.24  ? 111 LYS C CG    1 
ATOM   8780 C CD    . LYS C 3 111 ? 116.603 142.664 137.294 1.00 61.79  ? 111 LYS C CD    1 
ATOM   8781 C CE    . LYS C 3 111 ? 115.576 141.558 137.097 1.00 62.32  ? 111 LYS C CE    1 
ATOM   8782 N NZ    . LYS C 3 111 ? 114.810 141.724 135.832 1.00 67.64  ? 111 LYS C NZ    1 
ATOM   8783 N N     . GLU C 3 112 ? 121.564 142.025 136.061 1.00 60.45  ? 112 GLU C N     1 
ATOM   8784 C CA    . GLU C 3 112 ? 122.650 142.985 136.194 1.00 63.44  ? 112 GLU C CA    1 
ATOM   8785 C C     . GLU C 3 112 ? 123.834 142.671 135.286 1.00 64.71  ? 112 GLU C C     1 
ATOM   8786 O O     . GLU C 3 112 ? 124.851 143.368 135.366 1.00 65.13  ? 112 GLU C O     1 
ATOM   8787 C CB    . GLU C 3 112 ? 123.120 143.051 137.654 1.00 66.59  ? 112 GLU C CB    1 
ATOM   8788 C CG    . GLU C 3 112 ? 121.996 143.146 138.685 1.00 67.34  ? 112 GLU C CG    1 
ATOM   8789 C CD    . GLU C 3 112 ? 121.245 144.468 138.639 1.00 65.47  ? 112 GLU C CD    1 
ATOM   8790 O OE1   . GLU C 3 112 ? 121.716 145.405 137.962 1.00 66.59  ? 112 GLU C OE1   1 
ATOM   8791 O OE2   . GLU C 3 112 ? 120.183 144.571 139.288 1.00 64.41  ? 112 GLU C OE2   1 
ATOM   8792 N N     . ARG C 3 113 ? 123.719 141.643 134.443 1.00 64.06  ? 113 ARG C N     1 
ATOM   8793 C CA    . ARG C 3 113 ? 124.762 141.188 133.512 1.00 67.43  ? 113 ARG C CA    1 
ATOM   8794 C C     . ARG C 3 113 ? 126.138 141.126 134.185 1.00 66.11  ? 113 ARG C C     1 
ATOM   8795 O O     . ARG C 3 113 ? 127.105 141.766 133.768 1.00 64.21  ? 113 ARG C O     1 
ATOM   8796 C CB    . ARG C 3 113 ? 124.787 142.032 132.223 1.00 73.54  ? 113 ARG C CB    1 
ATOM   8797 C CG    . ARG C 3 113 ? 125.027 143.538 132.348 1.00 73.56  ? 113 ARG C CG    1 
ATOM   8798 C CD    . ARG C 3 113 ? 125.099 144.208 130.974 1.00 75.84  ? 113 ARG C CD    1 
ATOM   8799 N NE    . ARG C 3 113 ? 125.500 145.608 131.067 1.00 84.15  ? 113 ARG C NE    1 
ATOM   8800 C CZ    . ARG C 3 113 ? 125.674 146.414 130.027 1.00 87.01  ? 113 ARG C CZ    1 
ATOM   8801 N NH1   . ARG C 3 113 ? 125.480 145.995 128.786 1.00 85.46  ? 113 ARG C NH1   1 
ATOM   8802 N NH2   . ARG C 3 113 ? 126.053 147.671 130.236 1.00 86.48  ? 113 ARG C NH2   1 
ATOM   8803 N N     . VAL C 3 114 ? 126.208 140.316 135.240 1.00 67.07  ? 114 VAL C N     1 
ATOM   8804 C CA    . VAL C 3 114 ? 127.447 140.059 135.968 1.00 70.21  ? 114 VAL C CA    1 
ATOM   8805 C C     . VAL C 3 114 ? 127.560 138.561 136.221 1.00 66.54  ? 114 VAL C C     1 
ATOM   8806 O O     . VAL C 3 114 ? 126.573 137.903 136.567 1.00 63.25  ? 114 VAL C O     1 
ATOM   8807 C CB    . VAL C 3 114 ? 127.508 140.857 137.290 1.00 69.64  ? 114 VAL C CB    1 
ATOM   8808 C CG1   . VAL C 3 114 ? 126.286 140.569 138.155 1.00 65.76  ? 114 VAL C CG1   1 
ATOM   8809 C CG2   . VAL C 3 114 ? 128.793 140.551 138.048 1.00 64.11  ? 114 VAL C CG2   1 
ATOM   8810 N N     . GLN C 3 115 ? 128.762 138.017 136.032 1.00 67.37  ? 115 GLN C N     1 
ATOM   8811 C CA    . GLN C 3 115 ? 128.981 136.595 136.252 1.00 68.30  ? 115 GLN C CA    1 
ATOM   8812 C C     . GLN C 3 115 ? 128.827 136.248 137.730 1.00 66.55  ? 115 GLN C C     1 
ATOM   8813 O O     . GLN C 3 115 ? 129.067 137.073 138.615 1.00 65.23  ? 115 GLN C O     1 
ATOM   8814 C CB    . GLN C 3 115 ? 130.363 136.176 135.750 1.00 69.37  ? 115 GLN C CB    1 
ATOM   8815 C CG    . GLN C 3 115 ? 131.512 137.038 136.245 1.00 68.74  ? 115 GLN C CG    1 
ATOM   8816 C CD    . GLN C 3 115 ? 131.939 138.082 135.230 1.00 70.06  ? 115 GLN C CD    1 
ATOM   8817 O OE1   . GLN C 3 115 ? 131.175 138.984 134.888 1.00 68.70  ? 115 GLN C OE1   1 
ATOM   8818 N NE2   . GLN C 3 115 ? 133.166 137.959 134.737 1.00 71.84  ? 115 GLN C NE2   1 
ATOM   8819 N N     . ALA C 3 116 ? 128.410 135.005 137.987 1.00 67.85  ? 116 ALA C N     1 
ATOM   8820 C CA    . ALA C 3 116 ? 128.055 134.598 139.345 1.00 66.66  ? 116 ALA C CA    1 
ATOM   8821 C C     . ALA C 3 116 ? 129.266 134.573 140.270 1.00 65.63  ? 116 ALA C C     1 
ATOM   8822 O O     . ALA C 3 116 ? 129.187 135.035 141.415 1.00 63.98  ? 116 ALA C O     1 
ATOM   8823 C CB    . ALA C 3 116 ? 127.379 133.228 139.322 1.00 68.40  ? 116 ALA C CB    1 
ATOM   8824 N N     . ASP C 3 117 ? 130.394 134.040 139.796 1.00 66.21  ? 117 ASP C N     1 
ATOM   8825 C CA    . ASP C 3 117 ? 131.545 133.835 140.668 1.00 62.66  ? 117 ASP C CA    1 
ATOM   8826 C C     . ASP C 3 117 ? 132.174 135.139 141.140 1.00 61.26  ? 117 ASP C C     1 
ATOM   8827 O O     . ASP C 3 117 ? 132.980 135.116 142.077 1.00 61.56  ? 117 ASP C O     1 
ATOM   8828 C CB    . ASP C 3 117 ? 132.595 132.970 139.961 1.00 65.34  ? 117 ASP C CB    1 
ATOM   8829 C CG    . ASP C 3 117 ? 132.989 133.511 138.592 1.00 68.80  ? 117 ASP C CG    1 
ATOM   8830 O OD1   . ASP C 3 117 ? 132.660 134.672 138.270 1.00 67.43  ? 117 ASP C OD1   1 
ATOM   8831 O OD2   . ASP C 3 117 ? 133.632 132.761 137.828 1.00 70.33  ? 117 ASP C OD2   1 
ATOM   8832 N N     . GLN C 3 118 ? 131.834 136.267 140.524 1.00 59.44  ? 118 GLN C N     1 
ATOM   8833 C CA    . GLN C 3 118 ? 132.454 137.542 140.857 1.00 58.58  ? 118 GLN C CA    1 
ATOM   8834 C C     . GLN C 3 118 ? 131.691 138.342 141.907 1.00 53.87  ? 118 GLN C C     1 
ATOM   8835 O O     . GLN C 3 118 ? 132.119 139.452 142.239 1.00 53.03  ? 118 GLN C O     1 
ATOM   8836 C CB    . GLN C 3 118 ? 132.635 138.388 139.593 1.00 61.15  ? 118 GLN C CB    1 
ATOM   8837 C CG    . GLN C 3 118 ? 133.854 137.993 138.767 1.00 64.33  ? 118 GLN C CG    1 
ATOM   8838 C CD    . GLN C 3 118 ? 134.208 139.027 137.719 1.00 67.88  ? 118 GLN C CD    1 
ATOM   8839 O OE1   . GLN C 3 118 ? 133.460 139.976 137.488 1.00 65.30  ? 118 GLN C OE1   1 
ATOM   8840 N NE2   . GLN C 3 118 ? 135.359 138.854 137.080 1.00 69.72  ? 118 GLN C NE2   1 
ATOM   8841 N N     . PHE C 3 119 ? 130.586 137.824 142.441 1.00 51.72  ? 119 PHE C N     1 
ATOM   8842 C CA    . PHE C 3 119 ? 129.861 138.552 143.473 1.00 48.37  ? 119 PHE C CA    1 
ATOM   8843 C C     . PHE C 3 119 ? 129.148 137.580 144.401 1.00 49.79  ? 119 PHE C C     1 
ATOM   8844 O O     . PHE C 3 119 ? 128.969 136.401 144.087 1.00 54.24  ? 119 PHE C O     1 
ATOM   8845 C CB    . PHE C 3 119 ? 128.854 139.539 142.871 1.00 49.04  ? 119 PHE C CB    1 
ATOM   8846 C CG    . PHE C 3 119 ? 127.608 138.892 142.345 1.00 55.34  ? 119 PHE C CG    1 
ATOM   8847 C CD1   . PHE C 3 119 ? 127.594 138.313 141.092 1.00 61.06  ? 119 PHE C CD1   1 
ATOM   8848 C CD2   . PHE C 3 119 ? 126.446 138.874 143.100 1.00 55.70  ? 119 PHE C CD2   1 
ATOM   8849 C CE1   . PHE C 3 119 ? 126.450 137.721 140.602 1.00 63.58  ? 119 PHE C CE1   1 
ATOM   8850 C CE2   . PHE C 3 119 ? 125.298 138.281 142.615 1.00 58.58  ? 119 PHE C CE2   1 
ATOM   8851 C CZ    . PHE C 3 119 ? 125.300 137.705 141.365 1.00 62.17  ? 119 PHE C CZ    1 
ATOM   8852 N N     . TRP C 3 120 ? 128.743 138.103 145.558 1.00 47.66  ? 120 TRP C N     1 
ATOM   8853 C CA    . TRP C 3 120 ? 127.991 137.351 146.554 1.00 46.23  ? 120 TRP C CA    1 
ATOM   8854 C C     . TRP C 3 120 ? 126.921 138.257 147.147 1.00 45.09  ? 120 TRP C C     1 
ATOM   8855 O O     . TRP C 3 120 ? 126.910 139.466 146.912 1.00 47.60  ? 120 TRP C O     1 
ATOM   8856 C CB    . TRP C 3 120 ? 128.900 136.784 147.654 1.00 46.61  ? 120 TRP C CB    1 
ATOM   8857 C CG    . TRP C 3 120 ? 129.923 137.746 148.170 1.00 49.10  ? 120 TRP C CG    1 
ATOM   8858 C CD1   . TRP C 3 120 ? 131.058 138.153 147.535 1.00 49.64  ? 120 TRP C CD1   1 
ATOM   8859 C CD2   . TRP C 3 120 ? 129.915 138.405 149.439 1.00 44.24  ? 120 TRP C CD2   1 
ATOM   8860 N NE1   . TRP C 3 120 ? 131.754 139.032 148.327 1.00 46.08  ? 120 TRP C NE1   1 
ATOM   8861 C CE2   . TRP C 3 120 ? 131.071 139.203 149.502 1.00 42.02  ? 120 TRP C CE2   1 
ATOM   8862 C CE3   . TRP C 3 120 ? 129.037 138.402 150.525 1.00 44.28  ? 120 TRP C CE3   1 
ATOM   8863 C CZ2   . TRP C 3 120 ? 131.372 139.989 150.606 1.00 44.24  ? 120 TRP C CZ2   1 
ATOM   8864 C CZ3   . TRP C 3 120 ? 129.339 139.179 151.616 1.00 46.51  ? 120 TRP C CZ3   1 
ATOM   8865 C CH2   . TRP C 3 120 ? 130.491 139.967 151.649 1.00 46.70  ? 120 TRP C CH2   1 
ATOM   8866 N N     . LEU C 3 121 ? 126.000 137.662 147.897 1.00 43.71  ? 121 LEU C N     1 
ATOM   8867 C CA    . LEU C 3 121 ? 124.863 138.394 148.436 1.00 46.16  ? 121 LEU C CA    1 
ATOM   8868 C C     . LEU C 3 121 ? 124.931 138.474 149.955 1.00 49.61  ? 121 LEU C C     1 
ATOM   8869 O O     . LEU C 3 121 ? 125.470 137.586 150.620 1.00 54.33  ? 121 LEU C O     1 
ATOM   8870 C CB    . LEU C 3 121 ? 123.541 137.747 148.012 1.00 46.91  ? 121 LEU C CB    1 
ATOM   8871 C CG    . LEU C 3 121 ? 123.215 137.819 146.520 1.00 49.30  ? 121 LEU C CG    1 
ATOM   8872 C CD1   . LEU C 3 121 ? 121.885 137.141 146.222 1.00 53.99  ? 121 LEU C CD1   1 
ATOM   8873 C CD2   . LEU C 3 121 ? 123.200 139.260 146.050 1.00 50.32  ? 121 LEU C CD2   1 
ATOM   8874 N N     . SER C 3 122 ? 124.370 139.552 150.499 1.00 46.17  ? 122 SER C N     1 
ATOM   8875 C CA    . SER C 3 122 ? 124.304 139.755 151.939 1.00 43.55  ? 122 SER C CA    1 
ATOM   8876 C C     . SER C 3 122 ? 122.923 140.256 152.328 1.00 44.66  ? 122 SER C C     1 
ATOM   8877 O O     . SER C 3 122 ? 122.334 141.083 151.627 1.00 50.27  ? 122 SER C O     1 
ATOM   8878 C CB    . SER C 3 122 ? 125.357 140.758 152.413 1.00 47.76  ? 122 SER C CB    1 
ATOM   8879 O OG    . SER C 3 122 ? 126.659 140.320 152.090 1.00 48.63  ? 122 SER C OG    1 
ATOM   8880 N N     . PHE C 3 123 ? 122.417 139.759 153.454 1.00 45.78  ? 123 PHE C N     1 
ATOM   8881 C CA    . PHE C 3 123 ? 121.188 140.253 154.062 1.00 48.84  ? 123 PHE C CA    1 
ATOM   8882 C C     . PHE C 3 123 ? 121.495 140.683 155.488 1.00 57.75  ? 123 PHE C C     1 
ATOM   8883 O O     . PHE C 3 123 ? 122.016 139.888 156.279 1.00 57.47  ? 123 PHE C O     1 
ATOM   8884 C CB    . PHE C 3 123 ? 120.088 139.191 154.048 1.00 49.58  ? 123 PHE C CB    1 
ATOM   8885 C CG    . PHE C 3 123 ? 118.866 139.577 154.832 1.00 51.68  ? 123 PHE C CG    1 
ATOM   8886 C CD1   . PHE C 3 123 ? 117.946 140.464 154.309 1.00 52.66  ? 123 PHE C CD1   1 
ATOM   8887 C CD2   . PHE C 3 123 ? 118.640 139.051 156.091 1.00 56.96  ? 123 PHE C CD2   1 
ATOM   8888 C CE1   . PHE C 3 123 ? 116.824 140.821 155.026 1.00 56.22  ? 123 PHE C CE1   1 
ATOM   8889 C CE2   . PHE C 3 123 ? 117.521 139.403 156.812 1.00 58.64  ? 123 PHE C CE2   1 
ATOM   8890 C CZ    . PHE C 3 123 ? 116.611 140.291 156.278 1.00 58.69  ? 123 PHE C CZ    1 
ATOM   8891 N N     . GLU C 3 124 ? 121.176 141.939 155.808 1.00 57.90  ? 124 GLU C N     1 
ATOM   8892 C CA    . GLU C 3 124 ? 121.403 142.502 157.139 1.00 52.69  ? 124 GLU C CA    1 
ATOM   8893 C C     . GLU C 3 124 ? 122.840 142.276 157.601 1.00 52.47  ? 124 GLU C C     1 
ATOM   8894 O O     . GLU C 3 124 ? 123.102 141.954 158.761 1.00 55.14  ? 124 GLU C O     1 
ATOM   8895 C CB    . GLU C 3 124 ? 120.410 141.939 158.155 1.00 54.13  ? 124 GLU C CB    1 
ATOM   8896 C CG    . GLU C 3 124 ? 119.008 142.504 158.026 1.00 56.60  ? 124 GLU C CG    1 
ATOM   8897 C CD    . GLU C 3 124 ? 118.125 142.137 159.201 1.00 61.18  ? 124 GLU C CD    1 
ATOM   8898 O OE1   . GLU C 3 124 ? 118.564 141.329 160.046 1.00 64.87  ? 124 GLU C OE1   1 
ATOM   8899 O OE2   . GLU C 3 124 ? 116.993 142.659 159.281 1.00 60.94  ? 124 GLU C OE2   1 
ATOM   8900 N N     . GLY C 3 125 ? 123.785 142.445 156.677 1.00 51.77  ? 125 GLY C N     1 
ATOM   8901 C CA    . GLY C 3 125 ? 125.187 142.260 156.954 1.00 54.24  ? 125 GLY C CA    1 
ATOM   8902 C C     . GLY C 3 125 ? 125.659 140.824 156.868 1.00 56.48  ? 125 GLY C C     1 
ATOM   8903 O O     . GLY C 3 125 ? 126.817 140.583 156.514 1.00 58.27  ? 125 GLY C O     1 
ATOM   8904 N N     . ARG C 3 126 ? 124.792 139.867 157.174 1.00 58.42  ? 126 ARG C N     1 
ATOM   8905 C CA    . ARG C 3 126 ? 125.180 138.463 157.146 1.00 57.61  ? 126 ARG C CA    1 
ATOM   8906 C C     . ARG C 3 126 ? 125.249 137.975 155.704 1.00 53.69  ? 126 ARG C C     1 
ATOM   8907 O O     . ARG C 3 126 ? 124.268 138.119 154.966 1.00 56.49  ? 126 ARG C O     1 
ATOM   8908 C CB    . ARG C 3 126 ? 124.190 137.617 157.936 1.00 59.41  ? 126 ARG C CB    1 
ATOM   8909 C CG    . ARG C 3 126 ? 123.888 138.121 159.342 1.00 60.98  ? 126 ARG C CG    1 
ATOM   8910 C CD    . ARG C 3 126 ? 125.110 138.073 160.248 1.00 62.13  ? 126 ARG C CD    1 
ATOM   8911 N NE    . ARG C 3 126 ? 125.893 139.302 160.187 1.00 64.36  ? 126 ARG C NE    1 
ATOM   8912 C CZ    . ARG C 3 126 ? 126.981 139.535 160.907 1.00 69.67  ? 126 ARG C CZ    1 
ATOM   8913 N NH1   . ARG C 3 126 ? 127.450 138.638 161.760 1.00 66.87  ? 126 ARG C NH1   1 
ATOM   8914 N NH2   . ARG C 3 126 ? 127.614 140.696 160.770 1.00 71.79  ? 126 ARG C NH2   1 
ATOM   8915 N N     . PRO C 3 127 ? 126.370 137.414 155.262 1.00 50.05  ? 127 PRO C N     1 
ATOM   8916 C CA    . PRO C 3 127 ? 126.430 136.860 153.907 1.00 53.72  ? 127 PRO C CA    1 
ATOM   8917 C C     . PRO C 3 127 ? 125.499 135.669 153.753 1.00 59.81  ? 127 PRO C C     1 
ATOM   8918 O O     . PRO C 3 127 ? 125.198 134.954 154.711 1.00 63.92  ? 127 PRO C O     1 
ATOM   8919 C CB    . PRO C 3 127 ? 127.897 136.441 153.758 1.00 49.28  ? 127 PRO C CB    1 
ATOM   8920 C CG    . PRO C 3 127 ? 128.622 137.248 154.772 1.00 49.04  ? 127 PRO C CG    1 
ATOM   8921 C CD    . PRO C 3 127 ? 127.680 137.376 155.926 1.00 49.32  ? 127 PRO C CD    1 
ATOM   8922 N N     . MET C 3 128 ? 125.039 135.465 152.523 1.00 58.89  ? 128 MET C N     1 
ATOM   8923 C CA    . MET C 3 128 ? 124.105 134.400 152.190 1.00 62.85  ? 128 MET C CA    1 
ATOM   8924 C C     . MET C 3 128 ? 124.802 133.376 151.307 1.00 71.77  ? 128 MET C C     1 
ATOM   8925 O O     . MET C 3 128 ? 125.407 133.737 150.291 1.00 73.03  ? 128 MET C O     1 
ATOM   8926 C CB    . MET C 3 128 ? 122.878 134.961 151.473 1.00 62.08  ? 128 MET C CB    1 
ATOM   8927 C CG    . MET C 3 128 ? 122.425 136.315 151.985 1.00 60.48  ? 128 MET C CG    1 
ATOM   8928 S SD    . MET C 3 128 ? 121.278 137.120 150.853 1.00 61.84  ? 128 MET C SD    1 
ATOM   8929 C CE    . MET C 3 128 ? 119.906 135.976 150.897 1.00 63.25  ? 128 MET C CE    1 
ATOM   8930 N N     . ASP C 3 129 ? 124.715 132.107 151.691 1.00 76.26  ? 129 ASP C N     1 
ATOM   8931 C CA    . ASP C 3 129 ? 125.290 131.026 150.905 1.00 77.81  ? 129 ASP C CA    1 
ATOM   8932 C C     . ASP C 3 129 ? 124.300 130.556 149.847 1.00 76.96  ? 129 ASP C C     1 
ATOM   8933 O O     . ASP C 3 129 ? 123.084 130.557 150.059 1.00 77.14  ? 129 ASP C O     1 
ATOM   8934 C CB    . ASP C 3 129 ? 125.696 129.856 151.802 1.00 78.65  ? 129 ASP C CB    1 
ATOM   8935 C CG    . ASP C 3 129 ? 126.900 130.175 152.667 1.00 82.23  ? 129 ASP C CG    1 
ATOM   8936 O OD1   . ASP C 3 129 ? 127.428 131.303 152.562 1.00 80.44  ? 129 ASP C OD1   1 
ATOM   8937 O OD2   . ASP C 3 129 ? 127.321 129.298 153.450 1.00 82.40  ? 129 ASP C OD2   1 
ATOM   8938 N N     . ASP C 3 130 ? 124.840 130.152 148.695 1.00 77.33  ? 130 ASP C N     1 
ATOM   8939 C CA    . ASP C 3 130 ? 123.996 129.772 147.566 1.00 77.88  ? 130 ASP C CA    1 
ATOM   8940 C C     . ASP C 3 130 ? 123.177 128.523 147.870 1.00 78.46  ? 130 ASP C C     1 
ATOM   8941 O O     . ASP C 3 130 ? 122.006 128.433 147.483 1.00 77.62  ? 130 ASP C O     1 
ATOM   8942 C CB    . ASP C 3 130 ? 124.856 129.556 146.321 1.00 77.42  ? 130 ASP C CB    1 
ATOM   8943 C CG    . ASP C 3 130 ? 125.562 130.821 145.873 1.00 78.34  ? 130 ASP C CG    1 
ATOM   8944 O OD1   . ASP C 3 130 ? 125.304 131.890 146.464 1.00 76.33  ? 130 ASP C OD1   1 
ATOM   8945 O OD2   . ASP C 3 130 ? 126.376 130.746 144.928 1.00 77.96  ? 130 ASP C OD2   1 
ATOM   8946 N N     . GLU C 3 131 ? 123.776 127.546 148.556 1.00 78.28  ? 131 GLU C N     1 
ATOM   8947 C CA    . GLU C 3 131 ? 123.095 126.276 148.786 1.00 77.29  ? 131 GLU C CA    1 
ATOM   8948 C C     . GLU C 3 131 ? 121.912 126.424 149.734 1.00 73.78  ? 131 GLU C C     1 
ATOM   8949 O O     . GLU C 3 131 ? 120.906 125.723 149.579 1.00 73.85  ? 131 GLU C O     1 
ATOM   8950 C CB    . GLU C 3 131 ? 124.084 125.246 149.330 1.00 79.54  ? 131 GLU C CB    1 
ATOM   8951 C CG    . GLU C 3 131 ? 125.374 125.131 148.528 1.00 83.02  ? 131 GLU C CG    1 
ATOM   8952 C CD    . GLU C 3 131 ? 125.162 124.551 147.141 1.00 92.76  ? 131 GLU C CD    1 
ATOM   8953 O OE1   . GLU C 3 131 ? 124.117 123.907 146.911 1.00 93.05  ? 131 GLU C OE1   1 
ATOM   8954 O OE2   . GLU C 3 131 ? 126.046 124.739 146.279 1.00 96.55  ? 131 GLU C OE2   1 
ATOM   8955 N N     . HIS C 3 132 ? 122.011 127.317 150.713 1.00 72.47  ? 132 HIS C N     1 
ATOM   8956 C CA    . HIS C 3 132 ? 120.951 127.488 151.690 1.00 73.22  ? 132 HIS C CA    1 
ATOM   8957 C C     . HIS C 3 132 ? 119.725 128.133 151.048 1.00 70.55  ? 132 HIS C C     1 
ATOM   8958 O O     . HIS C 3 132 ? 119.831 128.810 150.023 1.00 72.29  ? 132 HIS C O     1 
ATOM   8959 C CB    . HIS C 3 132 ? 121.444 128.342 152.856 1.00 77.22  ? 132 HIS C CB    1 
ATOM   8960 C CG    . HIS C 3 132 ? 122.530 127.699 153.659 1.00 79.13  ? 132 HIS C CG    1 
ATOM   8961 N ND1   . HIS C 3 132 ? 122.326 127.215 154.933 1.00 82.88  ? 132 HIS C ND1   1 
ATOM   8962 C CD2   . HIS C 3 132 ? 123.830 127.456 153.369 1.00 79.46  ? 132 HIS C CD2   1 
ATOM   8963 C CE1   . HIS C 3 132 ? 123.454 126.704 155.394 1.00 84.37  ? 132 HIS C CE1   1 
ATOM   8964 N NE2   . HIS C 3 132 ? 124.382 126.838 154.464 1.00 84.24  ? 132 HIS C NE2   1 
ATOM   8965 N N     . PRO C 3 133 ? 118.546 127.921 151.623 1.00 68.77  ? 133 PRO C N     1 
ATOM   8966 C CA    . PRO C 3 133 ? 117.340 128.588 151.133 1.00 72.14  ? 133 PRO C CA    1 
ATOM   8967 C C     . PRO C 3 133 ? 117.158 129.962 151.770 1.00 75.51  ? 133 PRO C C     1 
ATOM   8968 O O     . PRO C 3 133 ? 117.896 130.367 152.670 1.00 78.46  ? 133 PRO C O     1 
ATOM   8969 C CB    . PRO C 3 133 ? 116.223 127.632 151.566 1.00 74.30  ? 133 PRO C CB    1 
ATOM   8970 C CG    . PRO C 3 133 ? 116.737 127.040 152.825 1.00 72.63  ? 133 PRO C CG    1 
ATOM   8971 C CD    . PRO C 3 133 ? 118.235 126.921 152.660 1.00 69.75  ? 133 PRO C CD    1 
ATOM   8972 N N     . LEU C 3 134 ? 116.144 130.678 151.277 1.00 75.07  ? 134 LEU C N     1 
ATOM   8973 C CA    . LEU C 3 134 ? 115.856 132.011 151.795 1.00 76.06  ? 134 LEU C CA    1 
ATOM   8974 C C     . LEU C 3 134 ? 115.231 131.961 153.184 1.00 73.45  ? 134 LEU C C     1 
ATOM   8975 O O     . LEU C 3 134 ? 115.345 132.927 153.946 1.00 73.84  ? 134 LEU C O     1 
ATOM   8976 C CB    . LEU C 3 134 ? 114.939 132.765 150.832 1.00 78.23  ? 134 LEU C CB    1 
ATOM   8977 C CG    . LEU C 3 134 ? 115.606 133.720 149.840 1.00 77.97  ? 134 LEU C CG    1 
ATOM   8978 C CD1   . LEU C 3 134 ? 116.608 132.999 148.950 1.00 75.68  ? 134 LEU C CD1   1 
ATOM   8979 C CD2   . LEU C 3 134 ? 114.554 134.425 149.003 1.00 75.38  ? 134 LEU C CD2   1 
ATOM   8980 N N     . GLU C 3 135 ? 114.563 130.857 153.525 1.00 71.81  ? 135 GLU C N     1 
ATOM   8981 C CA    . GLU C 3 135 ? 113.920 130.753 154.831 1.00 76.63  ? 135 GLU C CA    1 
ATOM   8982 C C     . GLU C 3 135 ? 114.933 130.819 155.966 1.00 79.62  ? 135 GLU C C     1 
ATOM   8983 O O     . GLU C 3 135 ? 114.635 131.369 157.033 1.00 81.08  ? 135 GLU C O     1 
ATOM   8984 C CB    . GLU C 3 135 ? 113.109 129.457 154.909 1.00 83.34  ? 135 GLU C CB    1 
ATOM   8985 C CG    . GLU C 3 135 ? 112.543 129.137 156.288 1.00 87.80  ? 135 GLU C CG    1 
ATOM   8986 C CD    . GLU C 3 135 ? 111.494 130.134 156.745 1.00 88.53  ? 135 GLU C CD    1 
ATOM   8987 O OE1   . GLU C 3 135 ? 110.880 130.798 155.883 1.00 85.08  ? 135 GLU C OE1   1 
ATOM   8988 O OE2   . GLU C 3 135 ? 111.283 130.253 157.970 1.00 88.75  ? 135 GLU C OE2   1 
ATOM   8989 N N     . GLU C 3 136 ? 116.134 130.280 155.758 1.00 79.26  ? 136 GLU C N     1 
ATOM   8990 C CA    . GLU C 3 136 ? 117.145 130.258 156.806 1.00 77.49  ? 136 GLU C CA    1 
ATOM   8991 C C     . GLU C 3 136 ? 117.875 131.586 156.964 1.00 77.53  ? 136 GLU C C     1 
ATOM   8992 O O     . GLU C 3 136 ? 118.685 131.719 157.887 1.00 78.06  ? 136 GLU C O     1 
ATOM   8993 C CB    . GLU C 3 136 ? 118.157 129.141 156.536 1.00 77.23  ? 136 GLU C CB    1 
ATOM   8994 C CG    . GLU C 3 136 ? 117.545 127.747 156.551 1.00 83.26  ? 136 GLU C CG    1 
ATOM   8995 C CD    . GLU C 3 136 ? 118.582 126.652 156.405 1.00 85.46  ? 136 GLU C CD    1 
ATOM   8996 O OE1   . GLU C 3 136 ? 119.784 126.977 156.326 1.00 86.09  ? 136 GLU C OE1   1 
ATOM   8997 O OE2   . GLU C 3 136 ? 118.193 125.465 156.370 1.00 85.19  ? 136 GLU C OE2   1 
ATOM   8998 N N     . TYR C 3 137 ? 117.615 132.564 156.096 1.00 76.92  ? 137 TYR C N     1 
ATOM   8999 C CA    . TYR C 3 137 ? 118.219 133.885 156.207 1.00 70.33  ? 137 TYR C CA    1 
ATOM   9000 C C     . TYR C 3 137 ? 117.207 134.978 156.520 1.00 65.38  ? 137 TYR C C     1 
ATOM   9001 O O     . TYR C 3 137 ? 117.592 136.146 156.628 1.00 62.09  ? 137 TYR C O     1 
ATOM   9002 C CB    . TYR C 3 137 ? 118.985 134.226 154.924 1.00 66.47  ? 137 TYR C CB    1 
ATOM   9003 C CG    . TYR C 3 137 ? 120.209 133.365 154.716 1.00 67.19  ? 137 TYR C CG    1 
ATOM   9004 C CD1   . TYR C 3 137 ? 120.970 132.939 155.795 1.00 68.53  ? 137 TYR C CD1   1 
ATOM   9005 C CD2   . TYR C 3 137 ? 120.594 132.967 153.445 1.00 69.38  ? 137 TYR C CD2   1 
ATOM   9006 C CE1   . TYR C 3 137 ? 122.085 132.147 155.613 1.00 72.11  ? 137 TYR C CE1   1 
ATOM   9007 C CE2   . TYR C 3 137 ? 121.704 132.174 153.254 1.00 71.24  ? 137 TYR C CE2   1 
ATOM   9008 C CZ    . TYR C 3 137 ? 122.449 131.769 154.339 1.00 74.50  ? 137 TYR C CZ    1 
ATOM   9009 O OH    . TYR C 3 137 ? 123.559 130.979 154.151 1.00 77.68  ? 137 TYR C OH    1 
ATOM   9010 N N     . GLY C 3 138 ? 115.933 134.632 156.673 1.00 67.25  ? 138 GLY C N     1 
ATOM   9011 C CA    . GLY C 3 138 ? 114.944 135.579 157.163 1.00 67.13  ? 138 GLY C CA    1 
ATOM   9012 C C     . GLY C 3 138 ? 114.695 136.772 156.268 1.00 71.62  ? 138 GLY C C     1 
ATOM   9013 O O     . GLY C 3 138 ? 114.586 137.902 156.761 1.00 72.49  ? 138 GLY C O     1 
ATOM   9014 N N     . LEU C 3 139 ? 114.599 136.551 154.960 1.00 74.42  ? 139 LEU C N     1 
ATOM   9015 C CA    . LEU C 3 139 ? 114.286 137.631 154.026 1.00 71.14  ? 139 LEU C CA    1 
ATOM   9016 C C     . LEU C 3 139 ? 112.807 137.968 154.156 1.00 73.89  ? 139 LEU C C     1 
ATOM   9017 O O     . LEU C 3 139 ? 111.944 137.243 153.657 1.00 73.36  ? 139 LEU C O     1 
ATOM   9018 C CB    . LEU C 3 139 ? 114.637 137.233 152.596 1.00 68.45  ? 139 LEU C CB    1 
ATOM   9019 C CG    . LEU C 3 139 ? 116.116 137.152 152.203 1.00 69.19  ? 139 LEU C CG    1 
ATOM   9020 C CD1   . LEU C 3 139 ? 116.736 135.838 152.647 1.00 70.78  ? 139 LEU C CD1   1 
ATOM   9021 C CD2   . LEU C 3 139 ? 116.291 137.348 150.705 1.00 67.99  ? 139 LEU C CD2   1 
ATOM   9022 N N     . MET C 3 140 ? 112.507 139.072 154.838 1.00 78.36  ? 140 MET C N     1 
ATOM   9023 C CA    . MET C 3 140 ? 111.128 139.497 155.017 1.00 81.01  ? 140 MET C CA    1 
ATOM   9024 C C     . MET C 3 140 ? 110.567 140.056 153.711 1.00 80.52  ? 140 MET C C     1 
ATOM   9025 O O     . MET C 3 140 ? 111.281 140.252 152.723 1.00 79.56  ? 140 MET C O     1 
ATOM   9026 C CB    . MET C 3 140 ? 111.024 140.542 156.128 1.00 80.16  ? 140 MET C CB    1 
ATOM   9027 C CG    . MET C 3 140 ? 111.059 139.980 157.544 1.00 85.42  ? 140 MET C CG    1 
ATOM   9028 S SD    . MET C 3 140 ? 109.614 138.983 157.972 1.00 99.96  ? 140 MET C SD    1 
ATOM   9029 C CE    . MET C 3 140 ? 110.262 137.323 157.777 1.00 81.40  ? 140 MET C CE    1 
ATOM   9030 N N     . LYS C 3 141 ? 109.261 140.311 153.718 1.00 79.83  ? 141 LYS C N     1 
ATOM   9031 C CA    . LYS C 3 141 ? 108.598 140.859 152.543 1.00 75.80  ? 141 LYS C CA    1 
ATOM   9032 C C     . LYS C 3 141 ? 109.130 142.254 152.241 1.00 71.04  ? 141 LYS C C     1 
ATOM   9033 O O     . LYS C 3 141 ? 109.168 143.120 153.120 1.00 70.20  ? 141 LYS C O     1 
ATOM   9034 C CB    . LYS C 3 141 ? 107.087 140.905 152.763 1.00 76.52  ? 141 LYS C CB    1 
ATOM   9035 C CG    . LYS C 3 141 ? 106.460 139.560 153.095 1.00 80.22  ? 141 LYS C CG    1 
ATOM   9036 C CD    . LYS C 3 141 ? 106.603 138.582 151.941 1.00 82.42  ? 141 LYS C CD    1 
ATOM   9037 C CE    . LYS C 3 141 ? 105.939 137.252 152.261 1.00 81.67  ? 141 LYS C CE    1 
ATOM   9038 N NZ    . LYS C 3 141 ? 106.030 136.289 151.128 1.00 79.54  ? 141 LYS C NZ    1 
ATOM   9039 N N     . GLY C 3 142 ? 109.537 142.471 150.993 1.00 68.17  ? 142 GLY C N     1 
ATOM   9040 C CA    . GLY C 3 142 ? 110.054 143.765 150.598 1.00 65.40  ? 142 GLY C CA    1 
ATOM   9041 C C     . GLY C 3 142 ? 111.373 144.143 151.228 1.00 66.48  ? 142 GLY C C     1 
ATOM   9042 O O     . GLY C 3 142 ? 111.690 145.332 151.309 1.00 70.00  ? 142 GLY C O     1 
ATOM   9043 N N     . CYS C 3 143 ? 112.156 143.166 151.679 1.00 63.95  ? 143 CYS C N     1 
ATOM   9044 C CA    . CYS C 3 143 ? 113.426 143.453 152.325 1.00 59.64  ? 143 CYS C CA    1 
ATOM   9045 C C     . CYS C 3 143 ? 114.476 143.832 151.283 1.00 55.25  ? 143 CYS C C     1 
ATOM   9046 O O     . CYS C 3 143 ? 114.199 143.938 150.085 1.00 57.96  ? 143 CYS C O     1 
ATOM   9047 C CB    . CYS C 3 143 ? 113.886 142.257 153.154 1.00 66.22  ? 143 CYS C CB    1 
ATOM   9048 S SG    . CYS C 3 143 ? 114.390 140.825 152.178 1.00 79.49  ? 143 CYS C SG    1 
ATOM   9049 N N     . THR C 3 144 ? 115.705 144.038 151.749 1.00 52.38  ? 144 THR C N     1 
ATOM   9050 C CA    . THR C 3 144 ? 116.809 144.445 150.894 1.00 51.28  ? 144 THR C CA    1 
ATOM   9051 C C     . THR C 3 144 ? 117.973 143.473 151.027 1.00 47.48  ? 144 THR C C     1 
ATOM   9052 O O     . THR C 3 144 ? 118.271 142.984 152.121 1.00 51.99  ? 144 THR C O     1 
ATOM   9053 C CB    . THR C 3 144 ? 117.276 145.870 151.224 1.00 55.94  ? 144 THR C CB    1 
ATOM   9054 O OG1   . THR C 3 144 ? 118.440 146.183 150.451 1.00 53.59  ? 144 THR C OG1   1 
ATOM   9055 C CG2   . THR C 3 144 ? 117.609 146.004 152.698 1.00 55.83  ? 144 THR C CG2   1 
ATOM   9056 N N     . VAL C 3 145 ? 118.611 143.187 149.898 1.00 44.35  ? 145 VAL C N     1 
ATOM   9057 C CA    . VAL C 3 145 ? 119.804 142.358 149.821 1.00 41.03  ? 145 VAL C CA    1 
ATOM   9058 C C     . VAL C 3 145 ? 120.859 143.132 149.044 1.00 40.79  ? 145 VAL C C     1 
ATOM   9059 O O     . VAL C 3 145 ? 120.553 143.757 148.023 1.00 49.35  ? 145 VAL C O     1 
ATOM   9060 C CB    . VAL C 3 145 ? 119.505 141.002 149.150 1.00 47.86  ? 145 VAL C CB    1 
ATOM   9061 C CG1   . VAL C 3 145 ? 120.783 140.210 148.930 1.00 49.51  ? 145 VAL C CG1   1 
ATOM   9062 C CG2   . VAL C 3 145 ? 118.516 140.201 149.987 1.00 54.62  ? 145 VAL C CG2   1 
ATOM   9063 N N     . PHE C 3 146 ? 122.096 143.088 149.527 1.00 40.94  ? 146 PHE C N     1 
ATOM   9064 C CA    . PHE C 3 146 ? 123.216 143.814 148.941 1.00 45.04  ? 146 PHE C CA    1 
ATOM   9065 C C     . PHE C 3 146 ? 124.070 142.853 148.127 1.00 41.59  ? 146 PHE C C     1 
ATOM   9066 O O     . PHE C 3 146 ? 124.365 141.746 148.591 1.00 47.21  ? 146 PHE C O     1 
ATOM   9067 C CB    . PHE C 3 146 ? 124.081 144.454 150.033 1.00 53.19  ? 146 PHE C CB    1 
ATOM   9068 C CG    . PHE C 3 146 ? 123.494 145.697 150.649 1.00 55.56  ? 146 PHE C CG    1 
ATOM   9069 C CD1   . PHE C 3 146 ? 122.286 145.661 151.327 1.00 54.64  ? 146 PHE C CD1   1 
ATOM   9070 C CD2   . PHE C 3 146 ? 124.180 146.896 150.581 1.00 56.84  ? 146 PHE C CD2   1 
ATOM   9071 C CE1   . PHE C 3 146 ? 121.763 146.805 151.900 1.00 57.73  ? 146 PHE C CE1   1 
ATOM   9072 C CE2   . PHE C 3 146 ? 123.665 148.041 151.153 1.00 60.08  ? 146 PHE C CE2   1 
ATOM   9073 C CZ    . PHE C 3 146 ? 122.454 147.995 151.813 1.00 61.26  ? 146 PHE C CZ    1 
ATOM   9074 N N     . MET C 3 147 ? 124.472 143.259 146.922 1.00 42.06  ? 147 MET C N     1 
ATOM   9075 C CA    . MET C 3 147 ? 125.511 142.517 146.224 1.00 46.12  ? 147 MET C CA    1 
ATOM   9076 C C     . MET C 3 147 ? 126.877 143.071 146.611 1.00 45.47  ? 147 MET C C     1 
ATOM   9077 O O     . MET C 3 147 ? 127.042 144.279 146.810 1.00 48.73  ? 147 MET C O     1 
ATOM   9078 C CB    . MET C 3 147 ? 125.311 142.568 144.706 1.00 51.04  ? 147 MET C CB    1 
ATOM   9079 C CG    . MET C 3 147 ? 125.991 143.727 143.994 1.00 57.13  ? 147 MET C CG    1 
ATOM   9080 S SD    . MET C 3 147 ? 126.391 143.374 142.267 1.00 73.72  ? 147 MET C SD    1 
ATOM   9081 C CE    . MET C 3 147 ? 124.810 142.819 141.634 1.00 66.09  ? 147 MET C CE    1 
ATOM   9082 N N     . ASN C 3 148 ? 127.847 142.174 146.765 1.00 39.52  ? 148 ASN C N     1 
ATOM   9083 C CA    . ASN C 3 148 ? 129.213 142.538 147.112 1.00 38.43  ? 148 ASN C CA    1 
ATOM   9084 C C     . ASN C 3 148 ? 130.159 141.863 146.132 1.00 38.27  ? 148 ASN C C     1 
ATOM   9085 O O     . ASN C 3 148 ? 130.152 140.633 146.005 1.00 42.63  ? 148 ASN C O     1 
ATOM   9086 C CB    . ASN C 3 148 ? 129.539 142.136 148.550 1.00 44.30  ? 148 ASN C CB    1 
ATOM   9087 C CG    . ASN C 3 148 ? 128.611 142.780 149.553 1.00 45.51  ? 148 ASN C CG    1 
ATOM   9088 O OD1   . ASN C 3 148 ? 127.841 142.102 150.228 1.00 46.57  ? 148 ASN C OD1   1 
ATOM   9089 N ND2   . ASN C 3 148 ? 128.672 144.101 149.652 1.00 44.63  ? 148 ASN C ND2   1 
ATOM   9090 N N     . LEU C 3 149 ? 130.959 142.665 145.439 1.00 38.76  ? 149 LEU C N     1 
ATOM   9091 C CA    . LEU C 3 149 ? 131.875 142.135 144.441 1.00 42.97  ? 149 LEU C CA    1 
ATOM   9092 C C     . LEU C 3 149 ? 133.129 141.570 145.093 1.00 42.98  ? 149 LEU C C     1 
ATOM   9093 O O     . LEU C 3 149 ? 133.606 142.081 146.110 1.00 45.82  ? 149 LEU C O     1 
ATOM   9094 C CB    . LEU C 3 149 ? 132.254 143.226 143.440 1.00 46.32  ? 149 LEU C CB    1 
ATOM   9095 C CG    . LEU C 3 149 ? 131.121 143.832 142.613 1.00 48.74  ? 149 LEU C CG    1 
ATOM   9096 C CD1   . LEU C 3 149 ? 131.661 144.892 141.661 1.00 52.68  ? 149 LEU C CD1   1 
ATOM   9097 C CD2   . LEU C 3 149 ? 130.385 142.743 141.848 1.00 49.22  ? 149 LEU C CD2   1 
ATOM   9098 N N     . ARG C 3 150 ? 133.659 140.503 144.503 1.00 43.20  ? 150 ARG C N     1 
ATOM   9099 C CA    . ARG C 3 150 ? 134.992 140.038 144.857 1.00 45.43  ? 150 ARG C CA    1 
ATOM   9100 C C     . ARG C 3 150 ? 136.023 140.992 144.267 1.00 47.26  ? 150 ARG C C     1 
ATOM   9101 O O     . ARG C 3 150 ? 135.930 141.374 143.097 1.00 47.33  ? 150 ARG C O     1 
ATOM   9102 C CB    . ARG C 3 150 ? 135.208 138.614 144.350 1.00 46.92  ? 150 ARG C CB    1 
ATOM   9103 C CG    . ARG C 3 150 ? 134.254 137.601 144.967 1.00 48.76  ? 150 ARG C CG    1 
ATOM   9104 C CD    . ARG C 3 150 ? 134.655 137.225 146.389 1.00 50.89  ? 150 ARG C CD    1 
ATOM   9105 N NE    . ARG C 3 150 ? 133.577 136.538 147.091 1.00 53.78  ? 150 ARG C NE    1 
ATOM   9106 C CZ    . ARG C 3 150 ? 133.302 135.247 146.967 1.00 59.69  ? 150 ARG C CZ    1 
ATOM   9107 N NH1   . ARG C 3 150 ? 134.020 134.459 146.183 1.00 57.86  ? 150 ARG C NH1   1 
ATOM   9108 N NH2   . ARG C 3 150 ? 132.279 134.733 147.643 1.00 65.65  ? 150 ARG C NH2   1 
ATOM   9109 N N     . LEU C 3 151 ? 136.999 141.387 145.077 1.00 48.94  ? 151 LEU C N     1 
ATOM   9110 C CA    . LEU C 3 151 ? 137.886 142.491 144.736 1.00 47.63  ? 151 LEU C CA    1 
ATOM   9111 C C     . LEU C 3 151 ? 139.147 141.968 144.065 1.00 50.08  ? 151 LEU C C     1 
ATOM   9112 O O     . LEU C 3 151 ? 139.785 141.036 144.566 1.00 51.47  ? 151 LEU C O     1 
ATOM   9113 C CB    . LEU C 3 151 ? 138.248 143.314 145.973 1.00 47.38  ? 151 LEU C CB    1 
ATOM   9114 C CG    . LEU C 3 151 ? 137.107 143.957 146.771 1.00 46.41  ? 151 LEU C CG    1 
ATOM   9115 C CD1   . LEU C 3 151 ? 136.005 144.472 145.878 1.00 45.43  ? 151 LEU C CD1   1 
ATOM   9116 C CD2   . LEU C 3 151 ? 136.536 142.992 147.772 1.00 45.57  ? 151 LEU C CD2   1 
ATOM   9117 N N     . ARG C 3 152 ? 139.494 142.575 142.928 1.00 53.36  ? 152 ARG C N     1 
ATOM   9118 C CA    . ARG C 3 152 ? 140.690 142.173 142.198 1.00 57.77  ? 152 ARG C CA    1 
ATOM   9119 C C     . ARG C 3 152 ? 141.937 142.350 143.053 1.00 57.55  ? 152 ARG C C     1 
ATOM   9120 O O     . ARG C 3 152 ? 142.731 141.415 143.214 1.00 57.61  ? 152 ARG C O     1 
ATOM   9121 C CB    . ARG C 3 152 ? 140.805 142.976 140.902 1.00 64.76  ? 152 ARG C CB    1 
ATOM   9122 C CG    . ARG C 3 152 ? 142.084 142.711 140.132 1.00 68.61  ? 152 ARG C CG    1 
ATOM   9123 C CD    . ARG C 3 152 ? 142.258 143.673 138.965 1.00 74.57  ? 152 ARG C CD    1 
ATOM   9124 N NE    . ARG C 3 152 ? 143.593 143.565 138.388 1.00 84.49  ? 152 ARG C NE    1 
ATOM   9125 C CZ    . ARG C 3 152 ? 144.035 144.271 137.355 1.00 87.36  ? 152 ARG C CZ    1 
ATOM   9126 N NH1   . ARG C 3 152 ? 143.266 145.154 136.738 1.00 88.44  ? 152 ARG C NH1   1 
ATOM   9127 N NH2   . ARG C 3 152 ? 145.282 144.088 136.932 1.00 88.28  ? 152 ARG C NH2   1 
ATOM   9128 N N     . GLY C 3 153 ? 142.124 143.536 143.614 1.00 58.41  ? 153 GLY C N     1 
ATOM   9129 C CA    . GLY C 3 153 ? 143.246 143.782 144.492 1.00 59.18  ? 153 GLY C CA    1 
ATOM   9130 C C     . GLY C 3 153 ? 143.683 145.231 144.450 1.00 62.11  ? 153 GLY C C     1 
ATOM   9131 O O     . GLY C 3 153 ? 143.021 146.086 143.866 1.00 61.46  ? 153 GLY C O     1 
ATOM   9132 N N     . GLY C 3 154 ? 144.826 145.478 145.087 1.00 61.81  ? 154 GLY C N     1 
ATOM   9133 C CA    . GLY C 3 154 ? 145.423 146.799 145.123 1.00 60.15  ? 154 GLY C CA    1 
ATOM   9134 C C     . GLY C 3 154 ? 146.916 146.763 145.426 1.00 58.15  ? 154 GLY C C     1 
ATOM   9135 O O     . GLY C 3 154 ? 147.347 146.192 146.424 1.00 59.36  ? 154 GLY C O     1 
HETATM 9136 P P     . AMP D 4 .   ? 148.812 146.894 144.116 1.00 84.27  ? 201 AMP C P     1 
HETATM 9137 O O1P   . AMP D 4 .   ? 147.847 147.496 143.131 1.00 87.54  ? 201 AMP C O1P   1 
HETATM 9138 O O2P   . AMP D 4 .   ? 150.005 147.768 144.398 1.00 65.42  ? 201 AMP C O2P   1 
HETATM 9139 O O3P   . AMP D 4 .   ? 148.195 146.267 145.336 1.00 79.47  ? 201 AMP C O3P   1 
HETATM 9140 O "O5'" . AMP D 4 .   ? 149.387 145.637 143.327 1.00 73.08  ? 201 AMP C "O5'" 1 
HETATM 9141 C "C5'" . AMP D 4 .   ? 149.718 144.429 144.006 1.00 62.83  ? 201 AMP C "C5'" 1 
HETATM 9142 C "C4'" . AMP D 4 .   ? 151.206 144.170 144.005 1.00 60.03  ? 201 AMP C "C4'" 1 
HETATM 9143 O "O4'" . AMP D 4 .   ? 151.449 142.744 144.151 1.00 60.12  ? 201 AMP C "O4'" 1 
HETATM 9144 C "C3'" . AMP D 4 .   ? 151.945 144.612 142.738 1.00 65.21  ? 201 AMP C "C3'" 1 
HETATM 9145 O "O3'" . AMP D 4 .   ? 153.164 145.258 143.097 1.00 64.99  ? 201 AMP C "O3'" 1 
HETATM 9146 C "C2'" . AMP D 4 .   ? 152.257 143.297 142.025 1.00 63.40  ? 201 AMP C "C2'" 1 
HETATM 9147 O "O2'" . AMP D 4 .   ? 153.428 143.322 141.241 1.00 68.27  ? 201 AMP C "O2'" 1 
HETATM 9148 C "C1'" . AMP D 4 .   ? 152.389 142.323 143.188 1.00 61.32  ? 201 AMP C "C1'" 1 
HETATM 9149 N N9    . AMP D 4 .   ? 152.104 140.934 142.808 1.00 62.47  ? 201 AMP C N9    1 
HETATM 9150 C C8    . AMP D 4 .   ? 151.147 140.548 141.945 1.00 65.30  ? 201 AMP C C8    1 
HETATM 9151 N N7    . AMP D 4 .   ? 151.134 139.205 141.758 1.00 66.59  ? 201 AMP C N7    1 
HETATM 9152 C C5    . AMP D 4 .   ? 152.126 138.703 142.508 1.00 61.49  ? 201 AMP C C5    1 
HETATM 9153 C C6    . AMP D 4 .   ? 152.669 137.352 142.779 1.00 57.76  ? 201 AMP C C6    1 
HETATM 9154 N N6    . AMP D 4 .   ? 152.158 136.238 142.209 1.00 61.16  ? 201 AMP C N6    1 
HETATM 9155 N N1    . AMP D 4 .   ? 153.711 137.258 143.623 1.00 55.92  ? 201 AMP C N1    1 
HETATM 9156 C C2    . AMP D 4 .   ? 154.248 138.340 144.206 1.00 53.91  ? 201 AMP C C2    1 
HETATM 9157 N N3    . AMP D 4 .   ? 153.805 139.593 144.014 1.00 53.26  ? 201 AMP C N3    1 
HETATM 9158 C C4    . AMP D 4 .   ? 152.767 139.843 143.189 1.00 57.86  ? 201 AMP C C4    1 
# 
