data_9JQW
# 
_entry.id   9JQW 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JQW         pdb_00009jqw 10.2210/pdb9jqw/pdb 
WWPDB D_1300052001 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-06 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JQW 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              tao.wan@biortus.bio 
_pdbx_contact_author.name_first         Tao 
_pdbx_contact_author.name_last          Wan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1833-2540 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wan, T.'  1 ? 
'Wang, F.' 2 ? 
'Lv, Z.'   3 ? 
'Lin, D.'  4 ? 
'Pan, W.'  5 ? 
'Sang, C.' 6 ? 
'Sun, J.'  7 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'The Crystal Structure of LCC6-Active from Biortus' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wan, T.'  1 ? 
primary 'Wang, F.' 2 ? 
primary 'Lv, Z.'   3 ? 
primary 'Lin, D.'  4 ? 
primary 'Pan, W.'  5 ? 
primary 'Sang, C.' 6 ? 
primary 'Sun, J.'  7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Leaf-branch compost cutinase' 27763.619 2   ? ? ? ? 
2 non-polymer syn GLYCEROL                       92.094    1   ? ? ? ? 
3 non-polymer syn 1,2-ETHANEDIOL                 62.068    3   ? ? ? ? 
4 non-polymer syn 'SULFATE ION'                  96.063    1   ? ? ? ? 
5 water       nat water                          18.015    481 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SNPYLVGPEPTLESLQKLGPFEVGTYTVPASSVTGFGGGVIYYPVNTDKKFPGIVMAPGYTADASSLDWLGKHLASHGFV
VFVLNHLSKTDDADAVADELAAGLEYLKTKSPAEVQARLDASRMGVAGHSMGGGGTLILAERDPSLKAAVPLTPWHTDKK
FNTKVPVLIIGAEADTVAPVSQHALPFFENLPKDTPKIYAVLCNASHIAPNSNNAAIKIYTVSWFKLFLCDDTRYRKFLC
NVNDPALCDFKSNNLFCS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SNPYLVGPEPTLESLQKLGPFEVGTYTVPASSVTGFGGGVIYYPVNTDKKFPGIVMAPGYTADASSLDWLGKHLASHGFV
VFVLNHLSKTDDADAVADELAAGLEYLKTKSPAEVQARLDASRMGVAGHSMGGGGTLILAERDPSLKAAVPLTPWHTDKK
FNTKVPVLIIGAEADTVAPVSQHALPFFENLPKDTPKIYAVLCNASHIAPNSNNAAIKIYTVSWFKLFLCDDTRYRKFLC
NVNDPALCDFKSNNLFCS
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 GLYCEROL       GOL 
3 1,2-ETHANEDIOL EDO 
4 'SULFATE ION'  SO4 
5 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   ASN n 
1 3   PRO n 
1 4   TYR n 
1 5   LEU n 
1 6   VAL n 
1 7   GLY n 
1 8   PRO n 
1 9   GLU n 
1 10  PRO n 
1 11  THR n 
1 12  LEU n 
1 13  GLU n 
1 14  SER n 
1 15  LEU n 
1 16  GLN n 
1 17  LYS n 
1 18  LEU n 
1 19  GLY n 
1 20  PRO n 
1 21  PHE n 
1 22  GLU n 
1 23  VAL n 
1 24  GLY n 
1 25  THR n 
1 26  TYR n 
1 27  THR n 
1 28  VAL n 
1 29  PRO n 
1 30  ALA n 
1 31  SER n 
1 32  SER n 
1 33  VAL n 
1 34  THR n 
1 35  GLY n 
1 36  PHE n 
1 37  GLY n 
1 38  GLY n 
1 39  GLY n 
1 40  VAL n 
1 41  ILE n 
1 42  TYR n 
1 43  TYR n 
1 44  PRO n 
1 45  VAL n 
1 46  ASN n 
1 47  THR n 
1 48  ASP n 
1 49  LYS n 
1 50  LYS n 
1 51  PHE n 
1 52  PRO n 
1 53  GLY n 
1 54  ILE n 
1 55  VAL n 
1 56  MET n 
1 57  ALA n 
1 58  PRO n 
1 59  GLY n 
1 60  TYR n 
1 61  THR n 
1 62  ALA n 
1 63  ASP n 
1 64  ALA n 
1 65  SER n 
1 66  SER n 
1 67  LEU n 
1 68  ASP n 
1 69  TRP n 
1 70  LEU n 
1 71  GLY n 
1 72  LYS n 
1 73  HIS n 
1 74  LEU n 
1 75  ALA n 
1 76  SER n 
1 77  HIS n 
1 78  GLY n 
1 79  PHE n 
1 80  VAL n 
1 81  VAL n 
1 82  PHE n 
1 83  VAL n 
1 84  LEU n 
1 85  ASN n 
1 86  HIS n 
1 87  LEU n 
1 88  SER n 
1 89  LYS n 
1 90  THR n 
1 91  ASP n 
1 92  ASP n 
1 93  ALA n 
1 94  ASP n 
1 95  ALA n 
1 96  VAL n 
1 97  ALA n 
1 98  ASP n 
1 99  GLU n 
1 100 LEU n 
1 101 ALA n 
1 102 ALA n 
1 103 GLY n 
1 104 LEU n 
1 105 GLU n 
1 106 TYR n 
1 107 LEU n 
1 108 LYS n 
1 109 THR n 
1 110 LYS n 
1 111 SER n 
1 112 PRO n 
1 113 ALA n 
1 114 GLU n 
1 115 VAL n 
1 116 GLN n 
1 117 ALA n 
1 118 ARG n 
1 119 LEU n 
1 120 ASP n 
1 121 ALA n 
1 122 SER n 
1 123 ARG n 
1 124 MET n 
1 125 GLY n 
1 126 VAL n 
1 127 ALA n 
1 128 GLY n 
1 129 HIS n 
1 130 SER n 
1 131 MET n 
1 132 GLY n 
1 133 GLY n 
1 134 GLY n 
1 135 GLY n 
1 136 THR n 
1 137 LEU n 
1 138 ILE n 
1 139 LEU n 
1 140 ALA n 
1 141 GLU n 
1 142 ARG n 
1 143 ASP n 
1 144 PRO n 
1 145 SER n 
1 146 LEU n 
1 147 LYS n 
1 148 ALA n 
1 149 ALA n 
1 150 VAL n 
1 151 PRO n 
1 152 LEU n 
1 153 THR n 
1 154 PRO n 
1 155 TRP n 
1 156 HIS n 
1 157 THR n 
1 158 ASP n 
1 159 LYS n 
1 160 LYS n 
1 161 PHE n 
1 162 ASN n 
1 163 THR n 
1 164 LYS n 
1 165 VAL n 
1 166 PRO n 
1 167 VAL n 
1 168 LEU n 
1 169 ILE n 
1 170 ILE n 
1 171 GLY n 
1 172 ALA n 
1 173 GLU n 
1 174 ALA n 
1 175 ASP n 
1 176 THR n 
1 177 VAL n 
1 178 ALA n 
1 179 PRO n 
1 180 VAL n 
1 181 SER n 
1 182 GLN n 
1 183 HIS n 
1 184 ALA n 
1 185 LEU n 
1 186 PRO n 
1 187 PHE n 
1 188 PHE n 
1 189 GLU n 
1 190 ASN n 
1 191 LEU n 
1 192 PRO n 
1 193 LYS n 
1 194 ASP n 
1 195 THR n 
1 196 PRO n 
1 197 LYS n 
1 198 ILE n 
1 199 TYR n 
1 200 ALA n 
1 201 VAL n 
1 202 LEU n 
1 203 CYS n 
1 204 ASN n 
1 205 ALA n 
1 206 SER n 
1 207 HIS n 
1 208 ILE n 
1 209 ALA n 
1 210 PRO n 
1 211 ASN n 
1 212 SER n 
1 213 ASN n 
1 214 ASN n 
1 215 ALA n 
1 216 ALA n 
1 217 ILE n 
1 218 LYS n 
1 219 ILE n 
1 220 TYR n 
1 221 THR n 
1 222 VAL n 
1 223 SER n 
1 224 TRP n 
1 225 PHE n 
1 226 LYS n 
1 227 LEU n 
1 228 PHE n 
1 229 LEU n 
1 230 CYS n 
1 231 ASP n 
1 232 ASP n 
1 233 THR n 
1 234 ARG n 
1 235 TYR n 
1 236 ARG n 
1 237 LYS n 
1 238 PHE n 
1 239 LEU n 
1 240 CYS n 
1 241 ASN n 
1 242 VAL n 
1 243 ASN n 
1 244 ASP n 
1 245 PRO n 
1 246 ALA n 
1 247 LEU n 
1 248 CYS n 
1 249 ASP n 
1 250 PHE n 
1 251 LYS n 
1 252 SER n 
1 253 ASN n 
1 254 ASN n 
1 255 LEU n 
1 256 PHE n 
1 257 CYS n 
1 258 SER n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   258 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'unidentified prokaryotic organism' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2725 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                               'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                               'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL  'ETHYLENE GLYCOL'               'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE       ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL        'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE       ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                               'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                               'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ?                               'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   36  ?   ?   ?   A . n 
A 1 2   ASN 2   37  ?   ?   ?   A . n 
A 1 3   PRO 3   38  ?   ?   ?   A . n 
A 1 4   TYR 4   39  ?   ?   ?   A . n 
A 1 5   LEU 5   40  40  LEU LEU A . n 
A 1 6   VAL 6   41  41  VAL VAL A . n 
A 1 7   GLY 7   42  42  GLY GLY A . n 
A 1 8   PRO 8   43  43  PRO PRO A . n 
A 1 9   GLU 9   44  44  GLU GLU A . n 
A 1 10  PRO 10  45  45  PRO PRO A . n 
A 1 11  THR 11  46  46  THR THR A . n 
A 1 12  LEU 12  47  47  LEU LEU A . n 
A 1 13  GLU 13  48  48  GLU GLU A . n 
A 1 14  SER 14  49  49  SER SER A . n 
A 1 15  LEU 15  50  50  LEU LEU A . n 
A 1 16  GLN 16  51  51  GLN GLN A . n 
A 1 17  LYS 17  52  52  LYS LYS A . n 
A 1 18  LEU 18  53  53  LEU LEU A . n 
A 1 19  GLY 19  54  54  GLY GLY A . n 
A 1 20  PRO 20  55  55  PRO PRO A . n 
A 1 21  PHE 21  56  56  PHE PHE A . n 
A 1 22  GLU 22  57  57  GLU GLU A . n 
A 1 23  VAL 23  58  58  VAL VAL A . n 
A 1 24  GLY 24  59  59  GLY GLY A . n 
A 1 25  THR 25  60  60  THR THR A . n 
A 1 26  TYR 26  61  61  TYR TYR A . n 
A 1 27  THR 27  62  62  THR THR A . n 
A 1 28  VAL 28  63  63  VAL VAL A . n 
A 1 29  PRO 29  64  64  PRO PRO A . n 
A 1 30  ALA 30  65  65  ALA ALA A . n 
A 1 31  SER 31  66  66  SER SER A . n 
A 1 32  SER 32  67  67  SER SER A . n 
A 1 33  VAL 33  68  68  VAL VAL A . n 
A 1 34  THR 34  69  69  THR THR A . n 
A 1 35  GLY 35  70  70  GLY GLY A . n 
A 1 36  PHE 36  71  71  PHE PHE A . n 
A 1 37  GLY 37  72  72  GLY GLY A . n 
A 1 38  GLY 38  73  73  GLY GLY A . n 
A 1 39  GLY 39  74  74  GLY GLY A . n 
A 1 40  VAL 40  75  75  VAL VAL A . n 
A 1 41  ILE 41  76  76  ILE ILE A . n 
A 1 42  TYR 42  77  77  TYR TYR A . n 
A 1 43  TYR 43  78  78  TYR TYR A . n 
A 1 44  PRO 44  79  79  PRO PRO A . n 
A 1 45  VAL 45  80  80  VAL VAL A . n 
A 1 46  ASN 46  81  81  ASN ASN A . n 
A 1 47  THR 47  82  82  THR THR A . n 
A 1 48  ASP 48  83  83  ASP ASP A . n 
A 1 49  LYS 49  84  84  LYS LYS A . n 
A 1 50  LYS 50  85  85  LYS LYS A . n 
A 1 51  PHE 51  86  86  PHE PHE A . n 
A 1 52  PRO 52  87  87  PRO PRO A . n 
A 1 53  GLY 53  88  88  GLY GLY A . n 
A 1 54  ILE 54  89  89  ILE ILE A . n 
A 1 55  VAL 55  90  90  VAL VAL A . n 
A 1 56  MET 56  91  91  MET MET A . n 
A 1 57  ALA 57  92  92  ALA ALA A . n 
A 1 58  PRO 58  93  93  PRO PRO A . n 
A 1 59  GLY 59  94  94  GLY GLY A . n 
A 1 60  TYR 60  95  95  TYR TYR A . n 
A 1 61  THR 61  96  96  THR THR A . n 
A 1 62  ALA 62  97  97  ALA ALA A . n 
A 1 63  ASP 63  98  98  ASP ASP A . n 
A 1 64  ALA 64  99  99  ALA ALA A . n 
A 1 65  SER 65  100 100 SER SER A . n 
A 1 66  SER 66  101 101 SER SER A . n 
A 1 67  LEU 67  102 102 LEU LEU A . n 
A 1 68  ASP 68  103 103 ASP ASP A . n 
A 1 69  TRP 69  104 104 TRP TRP A . n 
A 1 70  LEU 70  105 105 LEU LEU A . n 
A 1 71  GLY 71  106 106 GLY GLY A . n 
A 1 72  LYS 72  107 107 LYS LYS A . n 
A 1 73  HIS 73  108 108 HIS HIS A . n 
A 1 74  LEU 74  109 109 LEU LEU A . n 
A 1 75  ALA 75  110 110 ALA ALA A . n 
A 1 76  SER 76  111 111 SER SER A . n 
A 1 77  HIS 77  112 112 HIS HIS A . n 
A 1 78  GLY 78  113 113 GLY GLY A . n 
A 1 79  PHE 79  114 114 PHE PHE A . n 
A 1 80  VAL 80  115 115 VAL VAL A . n 
A 1 81  VAL 81  116 116 VAL VAL A . n 
A 1 82  PHE 82  117 117 PHE PHE A . n 
A 1 83  VAL 83  118 118 VAL VAL A . n 
A 1 84  LEU 84  119 119 LEU LEU A . n 
A 1 85  ASN 85  120 120 ASN ASN A . n 
A 1 86  HIS 86  121 121 HIS HIS A . n 
A 1 87  LEU 87  122 122 LEU LEU A . n 
A 1 88  SER 88  123 123 SER SER A . n 
A 1 89  LYS 89  124 124 LYS LYS A . n 
A 1 90  THR 90  125 125 THR THR A . n 
A 1 91  ASP 91  126 126 ASP ASP A . n 
A 1 92  ASP 92  127 127 ASP ASP A . n 
A 1 93  ALA 93  128 128 ALA ALA A . n 
A 1 94  ASP 94  129 129 ASP ASP A . n 
A 1 95  ALA 95  130 130 ALA ALA A . n 
A 1 96  VAL 96  131 131 VAL VAL A . n 
A 1 97  ALA 97  132 132 ALA ALA A . n 
A 1 98  ASP 98  133 133 ASP ASP A . n 
A 1 99  GLU 99  134 134 GLU GLU A . n 
A 1 100 LEU 100 135 135 LEU LEU A . n 
A 1 101 ALA 101 136 136 ALA ALA A . n 
A 1 102 ALA 102 137 137 ALA ALA A . n 
A 1 103 GLY 103 138 138 GLY GLY A . n 
A 1 104 LEU 104 139 139 LEU LEU A . n 
A 1 105 GLU 105 140 140 GLU GLU A . n 
A 1 106 TYR 106 141 141 TYR TYR A . n 
A 1 107 LEU 107 142 142 LEU LEU A . n 
A 1 108 LYS 108 143 143 LYS LYS A . n 
A 1 109 THR 109 144 144 THR THR A . n 
A 1 110 LYS 110 145 145 LYS LYS A . n 
A 1 111 SER 111 146 146 SER SER A . n 
A 1 112 PRO 112 147 147 PRO PRO A . n 
A 1 113 ALA 113 148 148 ALA ALA A . n 
A 1 114 GLU 114 149 149 GLU GLU A . n 
A 1 115 VAL 115 150 150 VAL VAL A . n 
A 1 116 GLN 116 151 151 GLN GLN A . n 
A 1 117 ALA 117 152 152 ALA ALA A . n 
A 1 118 ARG 118 153 153 ARG ARG A . n 
A 1 119 LEU 119 154 154 LEU LEU A . n 
A 1 120 ASP 120 155 155 ASP ASP A . n 
A 1 121 ALA 121 156 156 ALA ALA A . n 
A 1 122 SER 122 157 157 SER SER A . n 
A 1 123 ARG 123 158 158 ARG ARG A . n 
A 1 124 MET 124 159 159 MET MET A . n 
A 1 125 GLY 125 160 160 GLY GLY A . n 
A 1 126 VAL 126 161 161 VAL VAL A . n 
A 1 127 ALA 127 162 162 ALA ALA A . n 
A 1 128 GLY 128 163 163 GLY GLY A . n 
A 1 129 HIS 129 164 164 HIS HIS A . n 
A 1 130 SER 130 165 165 SER SER A . n 
A 1 131 MET 131 166 166 MET MET A . n 
A 1 132 GLY 132 167 167 GLY GLY A . n 
A 1 133 GLY 133 168 168 GLY GLY A . n 
A 1 134 GLY 134 169 169 GLY GLY A . n 
A 1 135 GLY 135 170 170 GLY GLY A . n 
A 1 136 THR 136 171 171 THR THR A . n 
A 1 137 LEU 137 172 172 LEU LEU A . n 
A 1 138 ILE 138 173 173 ILE ILE A . n 
A 1 139 LEU 139 174 174 LEU LEU A . n 
A 1 140 ALA 140 175 175 ALA ALA A . n 
A 1 141 GLU 141 176 176 GLU GLU A . n 
A 1 142 ARG 142 177 177 ARG ARG A . n 
A 1 143 ASP 143 178 178 ASP ASP A . n 
A 1 144 PRO 144 179 179 PRO PRO A . n 
A 1 145 SER 145 180 180 SER SER A . n 
A 1 146 LEU 146 181 181 LEU LEU A . n 
A 1 147 LYS 147 182 182 LYS LYS A . n 
A 1 148 ALA 148 183 183 ALA ALA A . n 
A 1 149 ALA 149 184 184 ALA ALA A . n 
A 1 150 VAL 150 185 185 VAL VAL A . n 
A 1 151 PRO 151 186 186 PRO PRO A . n 
A 1 152 LEU 152 187 187 LEU LEU A . n 
A 1 153 THR 153 188 188 THR THR A . n 
A 1 154 PRO 154 189 189 PRO PRO A . n 
A 1 155 TRP 155 190 190 TRP TRP A . n 
A 1 156 HIS 156 191 191 HIS HIS A . n 
A 1 157 THR 157 192 192 THR THR A . n 
A 1 158 ASP 158 193 193 ASP ASP A . n 
A 1 159 LYS 159 194 194 LYS LYS A . n 
A 1 160 LYS 160 195 195 LYS LYS A . n 
A 1 161 PHE 161 196 196 PHE PHE A . n 
A 1 162 ASN 162 197 197 ASN ASN A . n 
A 1 163 THR 163 198 198 THR THR A . n 
A 1 164 LYS 164 199 199 LYS LYS A . n 
A 1 165 VAL 165 200 200 VAL VAL A . n 
A 1 166 PRO 166 201 201 PRO PRO A . n 
A 1 167 VAL 167 202 202 VAL VAL A . n 
A 1 168 LEU 168 203 203 LEU LEU A . n 
A 1 169 ILE 169 204 204 ILE ILE A . n 
A 1 170 ILE 170 205 205 ILE ILE A . n 
A 1 171 GLY 171 206 206 GLY GLY A . n 
A 1 172 ALA 172 207 207 ALA ALA A . n 
A 1 173 GLU 173 208 208 GLU GLU A . n 
A 1 174 ALA 174 209 209 ALA ALA A . n 
A 1 175 ASP 175 210 210 ASP ASP A . n 
A 1 176 THR 176 211 211 THR THR A . n 
A 1 177 VAL 177 212 212 VAL VAL A . n 
A 1 178 ALA 178 213 213 ALA ALA A . n 
A 1 179 PRO 179 214 214 PRO PRO A . n 
A 1 180 VAL 180 215 215 VAL VAL A . n 
A 1 181 SER 181 216 216 SER SER A . n 
A 1 182 GLN 182 217 217 GLN GLN A . n 
A 1 183 HIS 183 218 218 HIS HIS A . n 
A 1 184 ALA 184 219 219 ALA ALA A . n 
A 1 185 LEU 185 220 220 LEU LEU A . n 
A 1 186 PRO 186 221 221 PRO PRO A . n 
A 1 187 PHE 187 222 222 PHE PHE A . n 
A 1 188 PHE 188 223 223 PHE PHE A . n 
A 1 189 GLU 189 224 224 GLU GLU A . n 
A 1 190 ASN 190 225 225 ASN ASN A . n 
A 1 191 LEU 191 226 226 LEU LEU A . n 
A 1 192 PRO 192 227 227 PRO PRO A . n 
A 1 193 LYS 193 228 228 LYS LYS A . n 
A 1 194 ASP 194 229 229 ASP ASP A . n 
A 1 195 THR 195 230 230 THR THR A . n 
A 1 196 PRO 196 231 231 PRO PRO A . n 
A 1 197 LYS 197 232 232 LYS LYS A . n 
A 1 198 ILE 198 233 233 ILE ILE A . n 
A 1 199 TYR 199 234 234 TYR TYR A . n 
A 1 200 ALA 200 235 235 ALA ALA A . n 
A 1 201 VAL 201 236 236 VAL VAL A . n 
A 1 202 LEU 202 237 237 LEU LEU A . n 
A 1 203 CYS 203 238 238 CYS CYS A . n 
A 1 204 ASN 204 239 239 ASN ASN A . n 
A 1 205 ALA 205 240 240 ALA ALA A . n 
A 1 206 SER 206 241 241 SER SER A . n 
A 1 207 HIS 207 242 242 HIS HIS A . n 
A 1 208 ILE 208 243 243 ILE ILE A . n 
A 1 209 ALA 209 244 244 ALA ALA A . n 
A 1 210 PRO 210 245 245 PRO PRO A . n 
A 1 211 ASN 211 246 246 ASN ASN A . n 
A 1 212 SER 212 247 247 SER SER A . n 
A 1 213 ASN 213 248 248 ASN ASN A . n 
A 1 214 ASN 214 249 249 ASN ASN A . n 
A 1 215 ALA 215 250 250 ALA ALA A . n 
A 1 216 ALA 216 251 251 ALA ALA A . n 
A 1 217 ILE 217 252 252 ILE ILE A . n 
A 1 218 LYS 218 253 253 LYS LYS A . n 
A 1 219 ILE 219 254 254 ILE ILE A . n 
A 1 220 TYR 220 255 255 TYR TYR A . n 
A 1 221 THR 221 256 256 THR THR A . n 
A 1 222 VAL 222 257 257 VAL VAL A . n 
A 1 223 SER 223 258 258 SER SER A . n 
A 1 224 TRP 224 259 259 TRP TRP A . n 
A 1 225 PHE 225 260 260 PHE PHE A . n 
A 1 226 LYS 226 261 261 LYS LYS A . n 
A 1 227 LEU 227 262 262 LEU LEU A . n 
A 1 228 PHE 228 263 263 PHE PHE A . n 
A 1 229 LEU 229 264 264 LEU LEU A . n 
A 1 230 CYS 230 265 265 CYS CYS A . n 
A 1 231 ASP 231 266 266 ASP ASP A . n 
A 1 232 ASP 232 267 267 ASP ASP A . n 
A 1 233 THR 233 268 268 THR THR A . n 
A 1 234 ARG 234 269 269 ARG ARG A . n 
A 1 235 TYR 235 270 270 TYR TYR A . n 
A 1 236 ARG 236 271 271 ARG ARG A . n 
A 1 237 LYS 237 272 272 LYS LYS A . n 
A 1 238 PHE 238 273 273 PHE PHE A . n 
A 1 239 LEU 239 274 274 LEU LEU A . n 
A 1 240 CYS 240 275 275 CYS CYS A . n 
A 1 241 ASN 241 276 276 ASN ASN A . n 
A 1 242 VAL 242 277 277 VAL VAL A . n 
A 1 243 ASN 243 278 278 ASN ASN A . n 
A 1 244 ASP 244 279 279 ASP ASP A . n 
A 1 245 PRO 245 280 280 PRO PRO A . n 
A 1 246 ALA 246 281 281 ALA ALA A . n 
A 1 247 LEU 247 282 282 LEU LEU A . n 
A 1 248 CYS 248 283 283 CYS CYS A . n 
A 1 249 ASP 249 284 284 ASP ASP A . n 
A 1 250 PHE 250 285 285 PHE PHE A . n 
A 1 251 LYS 251 286 286 LYS LYS A . n 
A 1 252 SER 252 287 287 SER SER A . n 
A 1 253 ASN 253 288 288 ASN ASN A . n 
A 1 254 ASN 254 289 289 ASN ASN A . n 
A 1 255 LEU 255 290 290 LEU LEU A . n 
A 1 256 PHE 256 291 291 PHE PHE A . n 
A 1 257 CYS 257 292 292 CYS CYS A . n 
A 1 258 SER 258 293 293 SER SER A . n 
B 1 1   SER 1   36  ?   ?   ?   B . n 
B 1 2   ASN 2   37  ?   ?   ?   B . n 
B 1 3   PRO 3   38  ?   ?   ?   B . n 
B 1 4   TYR 4   39  ?   ?   ?   B . n 
B 1 5   LEU 5   40  40  LEU LEU B . n 
B 1 6   VAL 6   41  41  VAL VAL B . n 
B 1 7   GLY 7   42  42  GLY GLY B . n 
B 1 8   PRO 8   43  43  PRO PRO B . n 
B 1 9   GLU 9   44  44  GLU GLU B . n 
B 1 10  PRO 10  45  45  PRO PRO B . n 
B 1 11  THR 11  46  46  THR THR B . n 
B 1 12  LEU 12  47  47  LEU LEU B . n 
B 1 13  GLU 13  48  48  GLU GLU B . n 
B 1 14  SER 14  49  49  SER SER B . n 
B 1 15  LEU 15  50  50  LEU LEU B . n 
B 1 16  GLN 16  51  51  GLN GLN B . n 
B 1 17  LYS 17  52  52  LYS LYS B . n 
B 1 18  LEU 18  53  53  LEU LEU B . n 
B 1 19  GLY 19  54  54  GLY GLY B . n 
B 1 20  PRO 20  55  55  PRO PRO B . n 
B 1 21  PHE 21  56  56  PHE PHE B . n 
B 1 22  GLU 22  57  57  GLU GLU B . n 
B 1 23  VAL 23  58  58  VAL VAL B . n 
B 1 24  GLY 24  59  59  GLY GLY B . n 
B 1 25  THR 25  60  60  THR THR B . n 
B 1 26  TYR 26  61  61  TYR TYR B . n 
B 1 27  THR 27  62  62  THR THR B . n 
B 1 28  VAL 28  63  63  VAL VAL B . n 
B 1 29  PRO 29  64  64  PRO PRO B . n 
B 1 30  ALA 30  65  65  ALA ALA B . n 
B 1 31  SER 31  66  66  SER SER B . n 
B 1 32  SER 32  67  67  SER SER B . n 
B 1 33  VAL 33  68  68  VAL VAL B . n 
B 1 34  THR 34  69  69  THR THR B . n 
B 1 35  GLY 35  70  70  GLY GLY B . n 
B 1 36  PHE 36  71  71  PHE PHE B . n 
B 1 37  GLY 37  72  72  GLY GLY B . n 
B 1 38  GLY 38  73  73  GLY GLY B . n 
B 1 39  GLY 39  74  74  GLY GLY B . n 
B 1 40  VAL 40  75  75  VAL VAL B . n 
B 1 41  ILE 41  76  76  ILE ILE B . n 
B 1 42  TYR 42  77  77  TYR TYR B . n 
B 1 43  TYR 43  78  78  TYR TYR B . n 
B 1 44  PRO 44  79  79  PRO PRO B . n 
B 1 45  VAL 45  80  80  VAL VAL B . n 
B 1 46  ASN 46  81  81  ASN ASN B . n 
B 1 47  THR 47  82  82  THR THR B . n 
B 1 48  ASP 48  83  83  ASP ASP B . n 
B 1 49  LYS 49  84  84  LYS LYS B . n 
B 1 50  LYS 50  85  85  LYS LYS B . n 
B 1 51  PHE 51  86  86  PHE PHE B . n 
B 1 52  PRO 52  87  87  PRO PRO B . n 
B 1 53  GLY 53  88  88  GLY GLY B . n 
B 1 54  ILE 54  89  89  ILE ILE B . n 
B 1 55  VAL 55  90  90  VAL VAL B . n 
B 1 56  MET 56  91  91  MET MET B . n 
B 1 57  ALA 57  92  92  ALA ALA B . n 
B 1 58  PRO 58  93  93  PRO PRO B . n 
B 1 59  GLY 59  94  94  GLY GLY B . n 
B 1 60  TYR 60  95  95  TYR TYR B . n 
B 1 61  THR 61  96  96  THR THR B . n 
B 1 62  ALA 62  97  97  ALA ALA B . n 
B 1 63  ASP 63  98  98  ASP ASP B . n 
B 1 64  ALA 64  99  99  ALA ALA B . n 
B 1 65  SER 65  100 100 SER SER B . n 
B 1 66  SER 66  101 101 SER SER B . n 
B 1 67  LEU 67  102 102 LEU LEU B . n 
B 1 68  ASP 68  103 103 ASP ASP B . n 
B 1 69  TRP 69  104 104 TRP TRP B . n 
B 1 70  LEU 70  105 105 LEU LEU B . n 
B 1 71  GLY 71  106 106 GLY GLY B . n 
B 1 72  LYS 72  107 107 LYS LYS B . n 
B 1 73  HIS 73  108 108 HIS HIS B . n 
B 1 74  LEU 74  109 109 LEU LEU B . n 
B 1 75  ALA 75  110 110 ALA ALA B . n 
B 1 76  SER 76  111 111 SER SER B . n 
B 1 77  HIS 77  112 112 HIS HIS B . n 
B 1 78  GLY 78  113 113 GLY GLY B . n 
B 1 79  PHE 79  114 114 PHE PHE B . n 
B 1 80  VAL 80  115 115 VAL VAL B . n 
B 1 81  VAL 81  116 116 VAL VAL B . n 
B 1 82  PHE 82  117 117 PHE PHE B . n 
B 1 83  VAL 83  118 118 VAL VAL B . n 
B 1 84  LEU 84  119 119 LEU LEU B . n 
B 1 85  ASN 85  120 120 ASN ASN B . n 
B 1 86  HIS 86  121 121 HIS HIS B . n 
B 1 87  LEU 87  122 122 LEU LEU B . n 
B 1 88  SER 88  123 123 SER SER B . n 
B 1 89  LYS 89  124 124 LYS LYS B . n 
B 1 90  THR 90  125 125 THR THR B . n 
B 1 91  ASP 91  126 126 ASP ASP B . n 
B 1 92  ASP 92  127 127 ASP ASP B . n 
B 1 93  ALA 93  128 128 ALA ALA B . n 
B 1 94  ASP 94  129 129 ASP ASP B . n 
B 1 95  ALA 95  130 130 ALA ALA B . n 
B 1 96  VAL 96  131 131 VAL VAL B . n 
B 1 97  ALA 97  132 132 ALA ALA B . n 
B 1 98  ASP 98  133 133 ASP ASP B . n 
B 1 99  GLU 99  134 134 GLU GLU B . n 
B 1 100 LEU 100 135 135 LEU LEU B . n 
B 1 101 ALA 101 136 136 ALA ALA B . n 
B 1 102 ALA 102 137 137 ALA ALA B . n 
B 1 103 GLY 103 138 138 GLY GLY B . n 
B 1 104 LEU 104 139 139 LEU LEU B . n 
B 1 105 GLU 105 140 140 GLU GLU B . n 
B 1 106 TYR 106 141 141 TYR TYR B . n 
B 1 107 LEU 107 142 142 LEU LEU B . n 
B 1 108 LYS 108 143 143 LYS LYS B . n 
B 1 109 THR 109 144 144 THR THR B . n 
B 1 110 LYS 110 145 145 LYS LYS B . n 
B 1 111 SER 111 146 146 SER SER B . n 
B 1 112 PRO 112 147 147 PRO PRO B . n 
B 1 113 ALA 113 148 148 ALA ALA B . n 
B 1 114 GLU 114 149 149 GLU GLU B . n 
B 1 115 VAL 115 150 150 VAL VAL B . n 
B 1 116 GLN 116 151 151 GLN GLN B . n 
B 1 117 ALA 117 152 152 ALA ALA B . n 
B 1 118 ARG 118 153 153 ARG ARG B . n 
B 1 119 LEU 119 154 154 LEU LEU B . n 
B 1 120 ASP 120 155 155 ASP ASP B . n 
B 1 121 ALA 121 156 156 ALA ALA B . n 
B 1 122 SER 122 157 157 SER SER B . n 
B 1 123 ARG 123 158 158 ARG ARG B . n 
B 1 124 MET 124 159 159 MET MET B . n 
B 1 125 GLY 125 160 160 GLY GLY B . n 
B 1 126 VAL 126 161 161 VAL VAL B . n 
B 1 127 ALA 127 162 162 ALA ALA B . n 
B 1 128 GLY 128 163 163 GLY GLY B . n 
B 1 129 HIS 129 164 164 HIS HIS B . n 
B 1 130 SER 130 165 165 SER SER B . n 
B 1 131 MET 131 166 166 MET MET B . n 
B 1 132 GLY 132 167 167 GLY GLY B . n 
B 1 133 GLY 133 168 168 GLY GLY B . n 
B 1 134 GLY 134 169 169 GLY GLY B . n 
B 1 135 GLY 135 170 170 GLY GLY B . n 
B 1 136 THR 136 171 171 THR THR B . n 
B 1 137 LEU 137 172 172 LEU LEU B . n 
B 1 138 ILE 138 173 173 ILE ILE B . n 
B 1 139 LEU 139 174 174 LEU LEU B . n 
B 1 140 ALA 140 175 175 ALA ALA B . n 
B 1 141 GLU 141 176 176 GLU GLU B . n 
B 1 142 ARG 142 177 177 ARG ARG B . n 
B 1 143 ASP 143 178 178 ASP ASP B . n 
B 1 144 PRO 144 179 179 PRO PRO B . n 
B 1 145 SER 145 180 180 SER SER B . n 
B 1 146 LEU 146 181 181 LEU LEU B . n 
B 1 147 LYS 147 182 182 LYS LYS B . n 
B 1 148 ALA 148 183 183 ALA ALA B . n 
B 1 149 ALA 149 184 184 ALA ALA B . n 
B 1 150 VAL 150 185 185 VAL VAL B . n 
B 1 151 PRO 151 186 186 PRO PRO B . n 
B 1 152 LEU 152 187 187 LEU LEU B . n 
B 1 153 THR 153 188 188 THR THR B . n 
B 1 154 PRO 154 189 189 PRO PRO B . n 
B 1 155 TRP 155 190 190 TRP TRP B . n 
B 1 156 HIS 156 191 191 HIS HIS B . n 
B 1 157 THR 157 192 192 THR THR B . n 
B 1 158 ASP 158 193 193 ASP ASP B . n 
B 1 159 LYS 159 194 194 LYS LYS B . n 
B 1 160 LYS 160 195 195 LYS LYS B . n 
B 1 161 PHE 161 196 196 PHE PHE B . n 
B 1 162 ASN 162 197 197 ASN ASN B . n 
B 1 163 THR 163 198 198 THR THR B . n 
B 1 164 LYS 164 199 199 LYS LYS B . n 
B 1 165 VAL 165 200 200 VAL VAL B . n 
B 1 166 PRO 166 201 201 PRO PRO B . n 
B 1 167 VAL 167 202 202 VAL VAL B . n 
B 1 168 LEU 168 203 203 LEU LEU B . n 
B 1 169 ILE 169 204 204 ILE ILE B . n 
B 1 170 ILE 170 205 205 ILE ILE B . n 
B 1 171 GLY 171 206 206 GLY GLY B . n 
B 1 172 ALA 172 207 207 ALA ALA B . n 
B 1 173 GLU 173 208 208 GLU GLU B . n 
B 1 174 ALA 174 209 209 ALA ALA B . n 
B 1 175 ASP 175 210 210 ASP ASP B . n 
B 1 176 THR 176 211 211 THR THR B . n 
B 1 177 VAL 177 212 212 VAL VAL B . n 
B 1 178 ALA 178 213 213 ALA ALA B . n 
B 1 179 PRO 179 214 214 PRO PRO B . n 
B 1 180 VAL 180 215 215 VAL VAL B . n 
B 1 181 SER 181 216 216 SER SER B . n 
B 1 182 GLN 182 217 217 GLN GLN B . n 
B 1 183 HIS 183 218 218 HIS HIS B . n 
B 1 184 ALA 184 219 219 ALA ALA B . n 
B 1 185 LEU 185 220 220 LEU LEU B . n 
B 1 186 PRO 186 221 221 PRO PRO B . n 
B 1 187 PHE 187 222 222 PHE PHE B . n 
B 1 188 PHE 188 223 223 PHE PHE B . n 
B 1 189 GLU 189 224 224 GLU GLU B . n 
B 1 190 ASN 190 225 225 ASN ASN B . n 
B 1 191 LEU 191 226 226 LEU LEU B . n 
B 1 192 PRO 192 227 227 PRO PRO B . n 
B 1 193 LYS 193 228 228 LYS LYS B . n 
B 1 194 ASP 194 229 229 ASP ASP B . n 
B 1 195 THR 195 230 230 THR THR B . n 
B 1 196 PRO 196 231 231 PRO PRO B . n 
B 1 197 LYS 197 232 232 LYS LYS B . n 
B 1 198 ILE 198 233 233 ILE ILE B . n 
B 1 199 TYR 199 234 234 TYR TYR B . n 
B 1 200 ALA 200 235 235 ALA ALA B . n 
B 1 201 VAL 201 236 236 VAL VAL B . n 
B 1 202 LEU 202 237 237 LEU LEU B . n 
B 1 203 CYS 203 238 238 CYS CYS B . n 
B 1 204 ASN 204 239 239 ASN ASN B . n 
B 1 205 ALA 205 240 240 ALA ALA B . n 
B 1 206 SER 206 241 241 SER SER B . n 
B 1 207 HIS 207 242 242 HIS HIS B . n 
B 1 208 ILE 208 243 243 ILE ILE B . n 
B 1 209 ALA 209 244 244 ALA ALA B . n 
B 1 210 PRO 210 245 245 PRO PRO B . n 
B 1 211 ASN 211 246 246 ASN ASN B . n 
B 1 212 SER 212 247 247 SER SER B . n 
B 1 213 ASN 213 248 248 ASN ASN B . n 
B 1 214 ASN 214 249 249 ASN ASN B . n 
B 1 215 ALA 215 250 250 ALA ALA B . n 
B 1 216 ALA 216 251 251 ALA ALA B . n 
B 1 217 ILE 217 252 252 ILE ILE B . n 
B 1 218 LYS 218 253 253 LYS LYS B . n 
B 1 219 ILE 219 254 254 ILE ILE B . n 
B 1 220 TYR 220 255 255 TYR TYR B . n 
B 1 221 THR 221 256 256 THR THR B . n 
B 1 222 VAL 222 257 257 VAL VAL B . n 
B 1 223 SER 223 258 258 SER SER B . n 
B 1 224 TRP 224 259 259 TRP TRP B . n 
B 1 225 PHE 225 260 260 PHE PHE B . n 
B 1 226 LYS 226 261 261 LYS LYS B . n 
B 1 227 LEU 227 262 262 LEU LEU B . n 
B 1 228 PHE 228 263 263 PHE PHE B . n 
B 1 229 LEU 229 264 264 LEU LEU B . n 
B 1 230 CYS 230 265 265 CYS CYS B . n 
B 1 231 ASP 231 266 266 ASP ASP B . n 
B 1 232 ASP 232 267 267 ASP ASP B . n 
B 1 233 THR 233 268 268 THR THR B . n 
B 1 234 ARG 234 269 269 ARG ARG B . n 
B 1 235 TYR 235 270 270 TYR TYR B . n 
B 1 236 ARG 236 271 271 ARG ARG B . n 
B 1 237 LYS 237 272 272 LYS LYS B . n 
B 1 238 PHE 238 273 273 PHE PHE B . n 
B 1 239 LEU 239 274 274 LEU LEU B . n 
B 1 240 CYS 240 275 275 CYS CYS B . n 
B 1 241 ASN 241 276 276 ASN ASN B . n 
B 1 242 VAL 242 277 277 VAL VAL B . n 
B 1 243 ASN 243 278 278 ASN ASN B . n 
B 1 244 ASP 244 279 279 ASP ASP B . n 
B 1 245 PRO 245 280 280 PRO PRO B . n 
B 1 246 ALA 246 281 281 ALA ALA B . n 
B 1 247 LEU 247 282 282 LEU LEU B . n 
B 1 248 CYS 248 283 283 CYS CYS B . n 
B 1 249 ASP 249 284 284 ASP ASP B . n 
B 1 250 PHE 250 285 285 PHE PHE B . n 
B 1 251 LYS 251 286 286 LYS LYS B . n 
B 1 252 SER 252 287 287 SER SER B . n 
B 1 253 ASN 253 288 288 ASN ASN B . n 
B 1 254 ASN 254 289 289 ASN ASN B . n 
B 1 255 LEU 255 290 290 LEU LEU B . n 
B 1 256 PHE 256 291 291 PHE PHE B . n 
B 1 257 CYS 257 292 292 CYS CYS B . n 
B 1 258 SER 258 293 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 GOL 1   301 301 GOL GOL A . 
D 3 EDO 1   302 302 EDO EDO A . 
E 4 SO4 1   301 301 SO4 SO4 B . 
F 3 EDO 1   302 302 EDO EDO B . 
G 3 EDO 1   303 303 EDO EDO B . 
H 5 HOH 1   401 208 HOH HOH A . 
H 5 HOH 2   402 325 HOH HOH A . 
H 5 HOH 3   403 229 HOH HOH A . 
H 5 HOH 4   404 250 HOH HOH A . 
H 5 HOH 5   405 273 HOH HOH A . 
H 5 HOH 6   406 183 HOH HOH A . 
H 5 HOH 7   407 365 HOH HOH A . 
H 5 HOH 8   408 207 HOH HOH A . 
H 5 HOH 9   409 3   HOH HOH A . 
H 5 HOH 10  410 302 HOH HOH A . 
H 5 HOH 11  411 357 HOH HOH A . 
H 5 HOH 12  412 142 HOH HOH A . 
H 5 HOH 13  413 327 HOH HOH A . 
H 5 HOH 14  414 336 HOH HOH A . 
H 5 HOH 15  415 253 HOH HOH A . 
H 5 HOH 16  416 94  HOH HOH A . 
H 5 HOH 17  417 117 HOH HOH A . 
H 5 HOH 18  418 440 HOH HOH A . 
H 5 HOH 19  419 313 HOH HOH A . 
H 5 HOH 20  420 466 HOH HOH A . 
H 5 HOH 21  421 76  HOH HOH A . 
H 5 HOH 22  422 75  HOH HOH A . 
H 5 HOH 23  423 257 HOH HOH A . 
H 5 HOH 24  424 136 HOH HOH A . 
H 5 HOH 25  425 12  HOH HOH A . 
H 5 HOH 26  426 72  HOH HOH A . 
H 5 HOH 27  427 214 HOH HOH A . 
H 5 HOH 28  428 148 HOH HOH A . 
H 5 HOH 29  429 79  HOH HOH A . 
H 5 HOH 30  430 205 HOH HOH A . 
H 5 HOH 31  431 346 HOH HOH A . 
H 5 HOH 32  432 47  HOH HOH A . 
H 5 HOH 33  433 249 HOH HOH A . 
H 5 HOH 34  434 182 HOH HOH A . 
H 5 HOH 35  435 45  HOH HOH A . 
H 5 HOH 36  436 5   HOH HOH A . 
H 5 HOH 37  437 441 HOH HOH A . 
H 5 HOH 38  438 391 HOH HOH A . 
H 5 HOH 39  439 362 HOH HOH A . 
H 5 HOH 40  440 228 HOH HOH A . 
H 5 HOH 41  441 41  HOH HOH A . 
H 5 HOH 42  442 83  HOH HOH A . 
H 5 HOH 43  443 245 HOH HOH A . 
H 5 HOH 44  444 91  HOH HOH A . 
H 5 HOH 45  445 34  HOH HOH A . 
H 5 HOH 46  446 16  HOH HOH A . 
H 5 HOH 47  447 469 HOH HOH A . 
H 5 HOH 48  448 118 HOH HOH A . 
H 5 HOH 49  449 33  HOH HOH A . 
H 5 HOH 50  450 48  HOH HOH A . 
H 5 HOH 51  451 8   HOH HOH A . 
H 5 HOH 52  452 452 HOH HOH A . 
H 5 HOH 53  453 191 HOH HOH A . 
H 5 HOH 54  454 82  HOH HOH A . 
H 5 HOH 55  455 211 HOH HOH A . 
H 5 HOH 56  456 326 HOH HOH A . 
H 5 HOH 57  457 310 HOH HOH A . 
H 5 HOH 58  458 38  HOH HOH A . 
H 5 HOH 59  459 22  HOH HOH A . 
H 5 HOH 60  460 435 HOH HOH A . 
H 5 HOH 61  461 135 HOH HOH A . 
H 5 HOH 62  462 36  HOH HOH A . 
H 5 HOH 63  463 11  HOH HOH A . 
H 5 HOH 64  464 392 HOH HOH A . 
H 5 HOH 65  465 219 HOH HOH A . 
H 5 HOH 66  466 147 HOH HOH A . 
H 5 HOH 67  467 132 HOH HOH A . 
H 5 HOH 68  468 126 HOH HOH A . 
H 5 HOH 69  469 14  HOH HOH A . 
H 5 HOH 70  470 111 HOH HOH A . 
H 5 HOH 71  471 212 HOH HOH A . 
H 5 HOH 72  472 359 HOH HOH A . 
H 5 HOH 73  473 54  HOH HOH A . 
H 5 HOH 74  474 237 HOH HOH A . 
H 5 HOH 75  475 60  HOH HOH A . 
H 5 HOH 76  476 305 HOH HOH A . 
H 5 HOH 77  477 433 HOH HOH A . 
H 5 HOH 78  478 40  HOH HOH A . 
H 5 HOH 79  479 69  HOH HOH A . 
H 5 HOH 80  480 456 HOH HOH A . 
H 5 HOH 81  481 4   HOH HOH A . 
H 5 HOH 82  482 227 HOH HOH A . 
H 5 HOH 83  483 421 HOH HOH A . 
H 5 HOH 84  484 157 HOH HOH A . 
H 5 HOH 85  485 324 HOH HOH A . 
H 5 HOH 86  486 251 HOH HOH A . 
H 5 HOH 87  487 153 HOH HOH A . 
H 5 HOH 88  488 66  HOH HOH A . 
H 5 HOH 89  489 84  HOH HOH A . 
H 5 HOH 90  490 338 HOH HOH A . 
H 5 HOH 91  491 173 HOH HOH A . 
H 5 HOH 92  492 64  HOH HOH A . 
H 5 HOH 93  493 154 HOH HOH A . 
H 5 HOH 94  494 2   HOH HOH A . 
H 5 HOH 95  495 65  HOH HOH A . 
H 5 HOH 96  496 454 HOH HOH A . 
H 5 HOH 97  497 241 HOH HOH A . 
H 5 HOH 98  498 109 HOH HOH A . 
H 5 HOH 99  499 221 HOH HOH A . 
H 5 HOH 100 500 80  HOH HOH A . 
H 5 HOH 101 501 202 HOH HOH A . 
H 5 HOH 102 502 134 HOH HOH A . 
H 5 HOH 103 503 216 HOH HOH A . 
H 5 HOH 104 504 31  HOH HOH A . 
H 5 HOH 105 505 246 HOH HOH A . 
H 5 HOH 106 506 270 HOH HOH A . 
H 5 HOH 107 507 271 HOH HOH A . 
H 5 HOH 108 508 478 HOH HOH A . 
H 5 HOH 109 509 123 HOH HOH A . 
H 5 HOH 110 510 339 HOH HOH A . 
H 5 HOH 111 511 32  HOH HOH A . 
H 5 HOH 112 512 197 HOH HOH A . 
H 5 HOH 113 513 63  HOH HOH A . 
H 5 HOH 114 514 113 HOH HOH A . 
H 5 HOH 115 515 238 HOH HOH A . 
H 5 HOH 116 516 96  HOH HOH A . 
H 5 HOH 117 517 389 HOH HOH A . 
H 5 HOH 118 518 81  HOH HOH A . 
H 5 HOH 119 519 312 HOH HOH A . 
H 5 HOH 120 520 232 HOH HOH A . 
H 5 HOH 121 521 201 HOH HOH A . 
H 5 HOH 122 522 116 HOH HOH A . 
H 5 HOH 123 523 189 HOH HOH A . 
H 5 HOH 124 524 152 HOH HOH A . 
H 5 HOH 125 525 98  HOH HOH A . 
H 5 HOH 126 526 67  HOH HOH A . 
H 5 HOH 127 527 49  HOH HOH A . 
H 5 HOH 128 528 431 HOH HOH A . 
H 5 HOH 129 529 17  HOH HOH A . 
H 5 HOH 130 530 196 HOH HOH A . 
H 5 HOH 131 531 167 HOH HOH A . 
H 5 HOH 132 532 242 HOH HOH A . 
H 5 HOH 133 533 106 HOH HOH A . 
H 5 HOH 134 534 56  HOH HOH A . 
H 5 HOH 135 535 398 HOH HOH A . 
H 5 HOH 136 536 156 HOH HOH A . 
H 5 HOH 137 537 112 HOH HOH A . 
H 5 HOH 138 538 97  HOH HOH A . 
H 5 HOH 139 539 6   HOH HOH A . 
H 5 HOH 140 540 192 HOH HOH A . 
H 5 HOH 141 541 293 HOH HOH A . 
H 5 HOH 142 542 160 HOH HOH A . 
H 5 HOH 143 543 114 HOH HOH A . 
H 5 HOH 144 544 471 HOH HOH A . 
H 5 HOH 145 545 18  HOH HOH A . 
H 5 HOH 146 546 146 HOH HOH A . 
H 5 HOH 147 547 402 HOH HOH A . 
H 5 HOH 148 548 120 HOH HOH A . 
H 5 HOH 149 549 133 HOH HOH A . 
H 5 HOH 150 550 190 HOH HOH A . 
H 5 HOH 151 551 26  HOH HOH A . 
H 5 HOH 152 552 145 HOH HOH A . 
H 5 HOH 153 553 360 HOH HOH A . 
H 5 HOH 154 554 236 HOH HOH A . 
H 5 HOH 155 555 215 HOH HOH A . 
H 5 HOH 156 556 1   HOH HOH A . 
H 5 HOH 157 557 161 HOH HOH A . 
H 5 HOH 158 558 396 HOH HOH A . 
H 5 HOH 159 559 244 HOH HOH A . 
H 5 HOH 160 560 351 HOH HOH A . 
H 5 HOH 161 561 443 HOH HOH A . 
H 5 HOH 162 562 269 HOH HOH A . 
H 5 HOH 163 563 143 HOH HOH A . 
H 5 HOH 164 564 131 HOH HOH A . 
H 5 HOH 165 565 400 HOH HOH A . 
H 5 HOH 166 566 272 HOH HOH A . 
H 5 HOH 167 567 292 HOH HOH A . 
H 5 HOH 168 568 311 HOH HOH A . 
H 5 HOH 169 569 177 HOH HOH A . 
H 5 HOH 170 570 473 HOH HOH A . 
H 5 HOH 171 571 128 HOH HOH A . 
H 5 HOH 172 572 328 HOH HOH A . 
H 5 HOH 173 573 403 HOH HOH A . 
H 5 HOH 174 574 404 HOH HOH A . 
H 5 HOH 175 575 352 HOH HOH A . 
H 5 HOH 176 576 475 HOH HOH A . 
H 5 HOH 177 577 385 HOH HOH A . 
H 5 HOH 178 578 353 HOH HOH A . 
H 5 HOH 179 579 139 HOH HOH A . 
H 5 HOH 180 580 176 HOH HOH A . 
H 5 HOH 181 581 408 HOH HOH A . 
H 5 HOH 182 582 77  HOH HOH A . 
H 5 HOH 183 583 399 HOH HOH A . 
H 5 HOH 184 584 379 HOH HOH A . 
H 5 HOH 185 585 224 HOH HOH A . 
H 5 HOH 186 586 239 HOH HOH A . 
H 5 HOH 187 587 361 HOH HOH A . 
H 5 HOH 188 588 468 HOH HOH A . 
H 5 HOH 189 589 318 HOH HOH A . 
H 5 HOH 190 590 149 HOH HOH A . 
H 5 HOH 191 591 119 HOH HOH A . 
H 5 HOH 192 592 474 HOH HOH A . 
H 5 HOH 193 593 233 HOH HOH A . 
H 5 HOH 194 594 259 HOH HOH A . 
H 5 HOH 195 595 463 HOH HOH A . 
H 5 HOH 196 596 43  HOH HOH A . 
H 5 HOH 197 597 340 HOH HOH A . 
H 5 HOH 198 598 390 HOH HOH A . 
H 5 HOH 199 599 453 HOH HOH A . 
H 5 HOH 200 600 55  HOH HOH A . 
H 5 HOH 201 601 220 HOH HOH A . 
H 5 HOH 202 602 73  HOH HOH A . 
H 5 HOH 203 603 436 HOH HOH A . 
H 5 HOH 204 604 37  HOH HOH A . 
H 5 HOH 205 605 276 HOH HOH A . 
H 5 HOH 206 606 401 HOH HOH A . 
H 5 HOH 207 607 472 HOH HOH A . 
H 5 HOH 208 608 303 HOH HOH A . 
H 5 HOH 209 609 172 HOH HOH A . 
H 5 HOH 210 610 384 HOH HOH A . 
H 5 HOH 211 611 332 HOH HOH A . 
H 5 HOH 212 612 393 HOH HOH A . 
H 5 HOH 213 613 198 HOH HOH A . 
H 5 HOH 214 614 299 HOH HOH A . 
H 5 HOH 215 615 316 HOH HOH A . 
H 5 HOH 216 616 395 HOH HOH A . 
H 5 HOH 217 617 121 HOH HOH A . 
H 5 HOH 218 618 287 HOH HOH A . 
H 5 HOH 219 619 174 HOH HOH A . 
H 5 HOH 220 620 394 HOH HOH A . 
H 5 HOH 221 621 218 HOH HOH A . 
H 5 HOH 222 622 337 HOH HOH A . 
H 5 HOH 223 623 320 HOH HOH A . 
H 5 HOH 224 624 382 HOH HOH A . 
H 5 HOH 225 625 195 HOH HOH A . 
H 5 HOH 226 626 300 HOH HOH A . 
H 5 HOH 227 627 284 HOH HOH A . 
H 5 HOH 228 628 306 HOH HOH A . 
H 5 HOH 229 629 322 HOH HOH A . 
H 5 HOH 230 630 285 HOH HOH A . 
H 5 HOH 231 631 319 HOH HOH A . 
H 5 HOH 232 632 317 HOH HOH A . 
H 5 HOH 233 633 349 HOH HOH A . 
H 5 HOH 234 634 432 HOH HOH A . 
H 5 HOH 235 635 323 HOH HOH A . 
H 5 HOH 236 636 321 HOH HOH A . 
H 5 HOH 237 637 308 HOH HOH A . 
H 5 HOH 238 638 95  HOH HOH A . 
H 5 HOH 239 639 307 HOH HOH A . 
H 5 HOH 240 640 286 HOH HOH A . 
H 5 HOH 241 641 367 HOH HOH A . 
H 5 HOH 242 642 455 HOH HOH A . 
H 5 HOH 243 643 333 HOH HOH A . 
H 5 HOH 244 644 439 HOH HOH A . 
H 5 HOH 245 645 315 HOH HOH A . 
H 5 HOH 246 646 380 HOH HOH A . 
H 5 HOH 247 647 260 HOH HOH A . 
H 5 HOH 248 648 301 HOH HOH A . 
H 5 HOH 249 649 314 HOH HOH A . 
I 5 HOH 1   401 477 HOH HOH B . 
I 5 HOH 2   402 85  HOH HOH B . 
I 5 HOH 3   403 144 HOH HOH B . 
I 5 HOH 4   404 426 HOH HOH B . 
I 5 HOH 5   405 420 HOH HOH B . 
I 5 HOH 6   406 15  HOH HOH B . 
I 5 HOH 7   407 52  HOH HOH B . 
I 5 HOH 8   408 464 HOH HOH B . 
I 5 HOH 9   409 169 HOH HOH B . 
I 5 HOH 10  410 480 HOH HOH B . 
I 5 HOH 11  411 347 HOH HOH B . 
I 5 HOH 12  412 170 HOH HOH B . 
I 5 HOH 13  413 467 HOH HOH B . 
I 5 HOH 14  414 370 HOH HOH B . 
I 5 HOH 15  415 415 HOH HOH B . 
I 5 HOH 16  416 381 HOH HOH B . 
I 5 HOH 17  417 266 HOH HOH B . 
I 5 HOH 18  418 200 HOH HOH B . 
I 5 HOH 19  419 127 HOH HOH B . 
I 5 HOH 20  420 28  HOH HOH B . 
I 5 HOH 21  421 53  HOH HOH B . 
I 5 HOH 22  422 416 HOH HOH B . 
I 5 HOH 23  423 186 HOH HOH B . 
I 5 HOH 24  424 461 HOH HOH B . 
I 5 HOH 25  425 342 HOH HOH B . 
I 5 HOH 26  426 204 HOH HOH B . 
I 5 HOH 27  427 226 HOH HOH B . 
I 5 HOH 28  428 101 HOH HOH B . 
I 5 HOH 29  429 39  HOH HOH B . 
I 5 HOH 30  430 429 HOH HOH B . 
I 5 HOH 31  431 168 HOH HOH B . 
I 5 HOH 32  432 125 HOH HOH B . 
I 5 HOH 33  433 93  HOH HOH B . 
I 5 HOH 34  434 175 HOH HOH B . 
I 5 HOH 35  435 377 HOH HOH B . 
I 5 HOH 36  436 164 HOH HOH B . 
I 5 HOH 37  437 10  HOH HOH B . 
I 5 HOH 38  438 413 HOH HOH B . 
I 5 HOH 39  439 275 HOH HOH B . 
I 5 HOH 40  440 209 HOH HOH B . 
I 5 HOH 41  441 437 HOH HOH B . 
I 5 HOH 42  442 422 HOH HOH B . 
I 5 HOH 43  443 234 HOH HOH B . 
I 5 HOH 44  444 248 HOH HOH B . 
I 5 HOH 45  445 58  HOH HOH B . 
I 5 HOH 46  446 138 HOH HOH B . 
I 5 HOH 47  447 281 HOH HOH B . 
I 5 HOH 48  448 181 HOH HOH B . 
I 5 HOH 49  449 122 HOH HOH B . 
I 5 HOH 50  450 350 HOH HOH B . 
I 5 HOH 51  451 188 HOH HOH B . 
I 5 HOH 52  452 217 HOH HOH B . 
I 5 HOH 53  453 368 HOH HOH B . 
I 5 HOH 54  454 21  HOH HOH B . 
I 5 HOH 55  455 203 HOH HOH B . 
I 5 HOH 56  456 225 HOH HOH B . 
I 5 HOH 57  457 71  HOH HOH B . 
I 5 HOH 58  458 68  HOH HOH B . 
I 5 HOH 59  459 289 HOH HOH B . 
I 5 HOH 60  460 162 HOH HOH B . 
I 5 HOH 61  461 369 HOH HOH B . 
I 5 HOH 62  462 373 HOH HOH B . 
I 5 HOH 63  463 356 HOH HOH B . 
I 5 HOH 64  464 358 HOH HOH B . 
I 5 HOH 65  465 25  HOH HOH B . 
I 5 HOH 66  466 44  HOH HOH B . 
I 5 HOH 67  467 255 HOH HOH B . 
I 5 HOH 68  468 206 HOH HOH B . 
I 5 HOH 69  469 409 HOH HOH B . 
I 5 HOH 70  470 187 HOH HOH B . 
I 5 HOH 71  471 345 HOH HOH B . 
I 5 HOH 72  472 78  HOH HOH B . 
I 5 HOH 73  473 23  HOH HOH B . 
I 5 HOH 74  474 179 HOH HOH B . 
I 5 HOH 75  475 13  HOH HOH B . 
I 5 HOH 76  476 89  HOH HOH B . 
I 5 HOH 77  477 171 HOH HOH B . 
I 5 HOH 78  478 294 HOH HOH B . 
I 5 HOH 79  479 230 HOH HOH B . 
I 5 HOH 80  480 103 HOH HOH B . 
I 5 HOH 81  481 290 HOH HOH B . 
I 5 HOH 82  482 19  HOH HOH B . 
I 5 HOH 83  483 35  HOH HOH B . 
I 5 HOH 84  484 297 HOH HOH B . 
I 5 HOH 85  485 210 HOH HOH B . 
I 5 HOH 86  486 130 HOH HOH B . 
I 5 HOH 87  487 476 HOH HOH B . 
I 5 HOH 88  488 7   HOH HOH B . 
I 5 HOH 89  489 155 HOH HOH B . 
I 5 HOH 90  490 470 HOH HOH B . 
I 5 HOH 91  491 99  HOH HOH B . 
I 5 HOH 92  492 61  HOH HOH B . 
I 5 HOH 93  493 150 HOH HOH B . 
I 5 HOH 94  494 180 HOH HOH B . 
I 5 HOH 95  495 86  HOH HOH B . 
I 5 HOH 96  496 29  HOH HOH B . 
I 5 HOH 97  497 115 HOH HOH B . 
I 5 HOH 98  498 24  HOH HOH B . 
I 5 HOH 99  499 277 HOH HOH B . 
I 5 HOH 100 500 20  HOH HOH B . 
I 5 HOH 101 501 419 HOH HOH B . 
I 5 HOH 102 502 334 HOH HOH B . 
I 5 HOH 103 503 344 HOH HOH B . 
I 5 HOH 104 504 376 HOH HOH B . 
I 5 HOH 105 505 50  HOH HOH B . 
I 5 HOH 106 506 417 HOH HOH B . 
I 5 HOH 107 507 309 HOH HOH B . 
I 5 HOH 108 508 110 HOH HOH B . 
I 5 HOH 109 509 30  HOH HOH B . 
I 5 HOH 110 510 165 HOH HOH B . 
I 5 HOH 111 511 104 HOH HOH B . 
I 5 HOH 112 512 27  HOH HOH B . 
I 5 HOH 113 513 163 HOH HOH B . 
I 5 HOH 114 514 295 HOH HOH B . 
I 5 HOH 115 515 107 HOH HOH B . 
I 5 HOH 116 516 423 HOH HOH B . 
I 5 HOH 117 517 193 HOH HOH B . 
I 5 HOH 118 518 458 HOH HOH B . 
I 5 HOH 119 519 105 HOH HOH B . 
I 5 HOH 120 520 102 HOH HOH B . 
I 5 HOH 121 521 252 HOH HOH B . 
I 5 HOH 122 522 335 HOH HOH B . 
I 5 HOH 123 523 178 HOH HOH B . 
I 5 HOH 124 524 87  HOH HOH B . 
I 5 HOH 125 525 256 HOH HOH B . 
I 5 HOH 126 526 129 HOH HOH B . 
I 5 HOH 127 527 88  HOH HOH B . 
I 5 HOH 128 528 282 HOH HOH B . 
I 5 HOH 129 529 449 HOH HOH B . 
I 5 HOH 130 530 42  HOH HOH B . 
I 5 HOH 131 531 479 HOH HOH B . 
I 5 HOH 132 532 364 HOH HOH B . 
I 5 HOH 133 533 448 HOH HOH B . 
I 5 HOH 134 534 158 HOH HOH B . 
I 5 HOH 135 535 459 HOH HOH B . 
I 5 HOH 136 536 288 HOH HOH B . 
I 5 HOH 137 537 427 HOH HOH B . 
I 5 HOH 138 538 235 HOH HOH B . 
I 5 HOH 139 539 330 HOH HOH B . 
I 5 HOH 140 540 261 HOH HOH B . 
I 5 HOH 141 541 70  HOH HOH B . 
I 5 HOH 142 542 57  HOH HOH B . 
I 5 HOH 143 543 62  HOH HOH B . 
I 5 HOH 144 544 199 HOH HOH B . 
I 5 HOH 145 545 343 HOH HOH B . 
I 5 HOH 146 546 378 HOH HOH B . 
I 5 HOH 147 547 445 HOH HOH B . 
I 5 HOH 148 548 9   HOH HOH B . 
I 5 HOH 149 549 100 HOH HOH B . 
I 5 HOH 150 550 405 HOH HOH B . 
I 5 HOH 151 551 140 HOH HOH B . 
I 5 HOH 152 552 267 HOH HOH B . 
I 5 HOH 153 553 108 HOH HOH B . 
I 5 HOH 154 554 231 HOH HOH B . 
I 5 HOH 155 555 51  HOH HOH B . 
I 5 HOH 156 556 457 HOH HOH B . 
I 5 HOH 157 557 90  HOH HOH B . 
I 5 HOH 158 558 428 HOH HOH B . 
I 5 HOH 159 559 341 HOH HOH B . 
I 5 HOH 160 560 59  HOH HOH B . 
I 5 HOH 161 561 430 HOH HOH B . 
I 5 HOH 162 562 442 HOH HOH B . 
I 5 HOH 163 563 46  HOH HOH B . 
I 5 HOH 164 564 159 HOH HOH B . 
I 5 HOH 165 565 375 HOH HOH B . 
I 5 HOH 166 566 263 HOH HOH B . 
I 5 HOH 167 567 407 HOH HOH B . 
I 5 HOH 168 568 213 HOH HOH B . 
I 5 HOH 169 569 363 HOH HOH B . 
I 5 HOH 170 570 141 HOH HOH B . 
I 5 HOH 171 571 298 HOH HOH B . 
I 5 HOH 172 572 137 HOH HOH B . 
I 5 HOH 173 573 465 HOH HOH B . 
I 5 HOH 174 574 278 HOH HOH B . 
I 5 HOH 175 575 151 HOH HOH B . 
I 5 HOH 176 576 434 HOH HOH B . 
I 5 HOH 177 577 296 HOH HOH B . 
I 5 HOH 178 578 412 HOH HOH B . 
I 5 HOH 179 579 274 HOH HOH B . 
I 5 HOH 180 580 265 HOH HOH B . 
I 5 HOH 181 581 460 HOH HOH B . 
I 5 HOH 182 582 124 HOH HOH B . 
I 5 HOH 183 583 354 HOH HOH B . 
I 5 HOH 184 584 383 HOH HOH B . 
I 5 HOH 185 585 262 HOH HOH B . 
I 5 HOH 186 586 450 HOH HOH B . 
I 5 HOH 187 587 291 HOH HOH B . 
I 5 HOH 188 588 268 HOH HOH B . 
I 5 HOH 189 589 264 HOH HOH B . 
I 5 HOH 190 590 280 HOH HOH B . 
I 5 HOH 191 591 247 HOH HOH B . 
I 5 HOH 192 592 371 HOH HOH B . 
I 5 HOH 193 593 444 HOH HOH B . 
I 5 HOH 194 594 348 HOH HOH B . 
I 5 HOH 195 595 92  HOH HOH B . 
I 5 HOH 196 596 194 HOH HOH B . 
I 5 HOH 197 597 254 HOH HOH B . 
I 5 HOH 198 598 374 HOH HOH B . 
I 5 HOH 199 599 397 HOH HOH B . 
I 5 HOH 200 600 372 HOH HOH B . 
I 5 HOH 201 601 425 HOH HOH B . 
I 5 HOH 202 602 451 HOH HOH B . 
I 5 HOH 203 603 184 HOH HOH B . 
I 5 HOH 204 604 240 HOH HOH B . 
I 5 HOH 205 605 258 HOH HOH B . 
I 5 HOH 206 606 355 HOH HOH B . 
I 5 HOH 207 607 185 HOH HOH B . 
I 5 HOH 208 608 406 HOH HOH B . 
I 5 HOH 209 609 222 HOH HOH B . 
I 5 HOH 210 610 447 HOH HOH B . 
I 5 HOH 211 611 329 HOH HOH B . 
I 5 HOH 212 612 462 HOH HOH B . 
I 5 HOH 213 613 366 HOH HOH B . 
I 5 HOH 214 614 243 HOH HOH B . 
I 5 HOH 215 615 331 HOH HOH B . 
I 5 HOH 216 616 411 HOH HOH B . 
I 5 HOH 217 617 418 HOH HOH B . 
I 5 HOH 218 618 446 HOH HOH B . 
I 5 HOH 219 619 223 HOH HOH B . 
I 5 HOH 220 620 438 HOH HOH B . 
I 5 HOH 221 621 166 HOH HOH B . 
I 5 HOH 222 622 279 HOH HOH B . 
I 5 HOH 223 623 386 HOH HOH B . 
I 5 HOH 224 624 304 HOH HOH B . 
I 5 HOH 225 625 388 HOH HOH B . 
I 5 HOH 226 626 74  HOH HOH B . 
I 5 HOH 227 627 481 HOH HOH B . 
I 5 HOH 228 628 424 HOH HOH B . 
I 5 HOH 229 629 283 HOH HOH B . 
I 5 HOH 230 630 387 HOH HOH B . 
I 5 HOH 231 631 414 HOH HOH B . 
I 5 HOH 232 632 410 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0352 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JQW 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     39.611 
_cell.length_a_esd                 ? 
_cell.length_b                     74.690 
_cell.length_b_esd                 ? 
_cell.length_c                     157.453 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JQW 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JQW 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.10 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          41.35 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2M (NH4)2SO4, 0.1M Mes pH6.5, 30% w/v Polyethylene glycol Monomethyl ether 5,000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-05-11 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979191 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL10U2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979191 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL10U2 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9JQW 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.05 
_reflns.d_resolution_low                               42.98 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     30250 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                10.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.194 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.05 
_reflns_shell.d_res_low                                     2.11 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2289 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.979 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.986 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            -0.000 
_refine.aniso_B[2][2]                            -0.016 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            1.003 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               20.111 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.967 
_refine.correlation_coeff_Fo_to_Fc_free          0.942 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9JQW 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.050 
_refine.ls_d_res_low                             42.979 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     30188 
_refine.ls_number_reflns_R_free                  1489 
_refine.ls_number_reflns_R_work                  28699 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.868 
_refine.ls_percent_reflns_R_free                 4.932 
_refine.ls_R_factor_all                          0.152 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2018 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1496 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      7vve 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.195 
_refine.pdbx_overall_ESU_R_Free                  0.164 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             4.519 
_refine.overall_SU_ML                            0.118 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.050 
_refine_hist.d_res_low                        42.979 
_refine_hist.number_atoms_solvent             481 
_refine_hist.number_atoms_total               4344 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3840 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         23 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012  4009 ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  3699 ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.336  1.645  5483 ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.451  1.565  8639 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 6.745  5.000  525  ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 5.425  5.000  10   ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.010 10.000 617  ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 16.530 10.000 152  ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.064  0.200  630  ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  4505 ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  767  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.215  0.200  877  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.190  0.200  3408 ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.178  0.200  1974 ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.080  0.200  2057 ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.232  0.200  372  ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.154  0.200  19   ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.172  0.200  71   ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.231  0.200  36   ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 1.524  2.034  2046 ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 1.523  2.034  2046 ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 2.299  3.038  2559 ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 2.298  3.040  2560 ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 2.469  2.331  1963 ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 2.468  2.332  1964 ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 3.746  3.371  2914 ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 3.745  3.373  2915 ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 5.608  33.653 4704 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.295  30.932 4540 ? r_lrange_other                 ? ? 
'X-RAY DIFFRACTION' ? 0.085  0.050  8194 ? r_ncsr_local_group_1           ? ? 
# 
loop_
_refine_ls_restr_ncs.pdbx_refine_id 
_refine_ls_restr_ncs.dom_id 
_refine_ls_restr_ncs.ncs_model_details 
_refine_ls_restr_ncs.rms_dev_B_iso 
_refine_ls_restr_ncs.rms_dev_position 
_refine_ls_restr_ncs.weight_B_iso 
_refine_ls_restr_ncs.weight_position 
_refine_ls_restr_ncs.pdbx_ordinal 
_refine_ls_restr_ncs.pdbx_type 
_refine_ls_restr_ncs.pdbx_asym_id 
_refine_ls_restr_ncs.pdbx_auth_asym_id 
_refine_ls_restr_ncs.pdbx_number 
_refine_ls_restr_ncs.pdbx_rms 
_refine_ls_restr_ncs.pdbx_weight 
_refine_ls_restr_ncs.pdbx_ens_id 
'X-RAY DIFFRACTION' 1 ? ? 0.08475 ? 0.05009 1 'Local ncs' ? A ? ? ? 1 
'X-RAY DIFFRACTION' 2 ? ? 0.08475 ? 0.05009 2 'Local ncs' ? A ? ? ? 1 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.050 2.103  2182 . 108 2067 99.6792  . 0.225 . . 0.222 . . . . . 0.192 . 20 . 0.962 0.945 0.286 
'X-RAY DIFFRACTION' 2.103 2.161  2130 . 128 1997 99.7653  . 0.210 . . 0.206 . . . . . 0.175 . 20 . 0.967 0.949 0.259 
'X-RAY DIFFRACTION' 2.161 2.223  2099 . 114 1980 99.7618  . 0.195 . . 0.192 . . . . . 0.161 . 20 . 0.973 0.959 0.255 
'X-RAY DIFFRACTION' 2.223 2.291  1992 . 94  1894 99.7992  . 0.176 . . 0.173 . . . . . 0.145 . 20 . 0.978 0.967 0.230 
'X-RAY DIFFRACTION' 2.291 2.366  1962 . 93  1866 99.8471  . 0.166 . . 0.162 . . . . . 0.133 . 20 . 0.981 0.962 0.244 
'X-RAY DIFFRACTION' 2.366 2.449  1919 . 70  1847 99.8958  . 0.155 . . 0.154 . . . . . 0.129 . 20 . 0.983 0.976 0.201 
'X-RAY DIFFRACTION' 2.449 2.541  1829 . 95  1732 99.8906  . 0.146 . . 0.143 . . . . . 0.122 . 20 . 0.986 0.978 0.192 
'X-RAY DIFFRACTION' 2.541 2.645  1791 . 84  1707 100.0000 . 0.142 . . 0.140 . . . . . 0.121 . 20 . 0.986 0.975 0.184 
'X-RAY DIFFRACTION' 2.645 2.762  1680 . 93  1586 99.9405  . 0.160 . . 0.155 . . . . . 0.132 . 20 . 0.984 0.966 0.246 
'X-RAY DIFFRACTION' 2.762 2.896  1639 . 78  1561 100.0000 . 0.143 . . 0.141 . . . . . 0.123 . 20 . 0.988 0.975 0.190 
'X-RAY DIFFRACTION' 2.896 3.052  1572 . 75  1497 100.0000 . 0.147 . . 0.145 . . . . . 0.127 . 20 . 0.986 0.976 0.184 
'X-RAY DIFFRACTION' 3.052 3.236  1474 . 77  1397 100.0000 . 0.147 . . 0.144 . . . . . 0.130 . 20 . 0.987 0.978 0.200 
'X-RAY DIFFRACTION' 3.236 3.458  1380 . 64  1315 99.9275  . 0.140 . . 0.138 . . . . . 0.127 . 20 . 0.989 0.981 0.176 
'X-RAY DIFFRACTION' 3.458 3.733  1315 . 63  1252 100.0000 . 0.137 . . 0.135 . . . . . 0.128 . 20 . 0.990 0.983 0.169 
'X-RAY DIFFRACTION' 3.733 4.086  1206 . 59  1147 100.0000 . 0.136 . . 0.134 . . . . . 0.126 . 20 . 0.990 0.984 0.169 
'X-RAY DIFFRACTION' 4.086 4.563  1100 . 48  1052 100.0000 . 0.115 . . 0.113 . . . . . 0.109 . 20 . 0.992 0.981 0.167 
'X-RAY DIFFRACTION' 4.563 5.259  995  . 49  946  100.0000 . 0.110 . . 0.110 . . . . . 0.107 . 20 . 0.994 0.994 0.118 
'X-RAY DIFFRACTION' 5.259 6.417  854  . 55  799  100.0000 . 0.160 . . 0.158 . . . . . 0.143 . 20 . 0.988 0.986 0.185 
'X-RAY DIFFRACTION' 6.417 8.976  670  . 26  644  100.0000 . 0.151 . . 0.146 . . . . . 0.142 . 20 . 0.988 0.962 0.302 
'X-RAY DIFFRACTION' 8.976 42.979 436  . 16  413  98.3945  . 0.210 . . 0.204 . . . . . 0.194 . 20 . 0.961 0.837 0.448 
# 
loop_
_struct_ncs_dom.id 
_struct_ncs_dom.pdbx_ens_id 
_struct_ncs_dom.details 
1 1 A 
2 1 A 
# 
loop_
_struct_ncs_dom_lim.pdbx_ens_id 
_struct_ncs_dom_lim.dom_id 
_struct_ncs_dom_lim.pdbx_component_id 
_struct_ncs_dom_lim.beg_label_asym_id 
_struct_ncs_dom_lim.beg_label_comp_id 
_struct_ncs_dom_lim.beg_label_seq_id 
_struct_ncs_dom_lim.beg_label_alt_id 
_struct_ncs_dom_lim.end_label_asym_id 
_struct_ncs_dom_lim.end_label_comp_id 
_struct_ncs_dom_lim.end_label_seq_id 
_struct_ncs_dom_lim.end_label_alt_id 
_struct_ncs_dom_lim.beg_auth_asym_id 
_struct_ncs_dom_lim.beg_auth_comp_id 
_struct_ncs_dom_lim.beg_auth_seq_id 
_struct_ncs_dom_lim.end_auth_asym_id 
_struct_ncs_dom_lim.end_auth_comp_id 
_struct_ncs_dom_lim.end_auth_seq_id 
_struct_ncs_dom_lim.pdbx_refine_code 
_struct_ncs_dom_lim.selection_details 
1 1 1 A LEU 5 . A PHE 256 . A LEU 40 A PHE 291 ? ? 
1 2 1 A LEU 5 . A PHE 256 . A LEU 40 A PHE 291 ? ? 
# 
_struct_ncs_ens.id        1 
_struct_ncs_ens.details   'Local NCS retraints between domains:       1       2' 
# 
_struct.entry_id                     9JQW 
_struct.title                        'The Crystal Structure of LCC6-Active from Biortus' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JQW 
_struct_keywords.text            'Hydrolase Serine esterase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 3 ? 
G N N 3 ? 
H N N 5 ? 
I N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9JQW 
_struct_ref.pdbx_db_accession          9JQW 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JQW A 1 ? 258 ? 9JQW 36 ? 293 ? 36 293 
2 1 9JQW B 1 ? 258 ? 9JQW 36 ? 293 ? 36 293 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly   ?    monomeric 1 
2 author_defined_assembly   ?    monomeric 1 
3 software_defined_assembly PISA dimeric   2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
3 'ABSA (A^2)' 2640  ? 
3 MORE         -26   ? 
3 'SSA (A^2)'  19140 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,H           
2 1 B,E,F,G,I         
3 1 A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 11  ? LYS A 17  ? THR A 46  LYS A 52  1 ? 7  
HELX_P HELX_P2  AA2 PRO A 29  ? VAL A 33  ? PRO A 64  VAL A 68  5 ? 5  
HELX_P HELX_P3  AA3 ASP A 63  ? SER A 66  ? ASP A 98  SER A 101 5 ? 4  
HELX_P HELX_P4  AA4 LEU A 67  ? HIS A 77  ? LEU A 102 HIS A 112 1 ? 11 
HELX_P HELX_P5  AA5 ASP A 92  ? LYS A 110 ? ASP A 127 LYS A 145 1 ? 19 
HELX_P HELX_P6  AA6 PRO A 112 ? ARG A 118 ? PRO A 147 ARG A 153 1 ? 7  
HELX_P HELX_P7  AA7 SER A 130 ? ASP A 143 ? SER A 165 ASP A 178 1 ? 14 
HELX_P HELX_P8  AA8 HIS A 183 ? ASN A 190 ? HIS A 218 ASN A 225 1 ? 8  
HELX_P HELX_P9  AA9 ILE A 208 ? SER A 212 ? ILE A 243 SER A 247 5 ? 5  
HELX_P HELX_P10 AB1 ASN A 214 ? ASP A 231 ? ASN A 249 ASP A 266 1 ? 18 
HELX_P HELX_P11 AB2 ASP A 232 ? CYS A 240 ? ASP A 267 CYS A 275 5 ? 9  
HELX_P HELX_P12 AB3 THR B 11  ? GLN B 16  ? THR B 46  GLN B 51  1 ? 6  
HELX_P HELX_P13 AB4 PRO B 29  ? VAL B 33  ? PRO B 64  VAL B 68  5 ? 5  
HELX_P HELX_P14 AB5 ASP B 63  ? SER B 66  ? ASP B 98  SER B 101 5 ? 4  
HELX_P HELX_P15 AB6 LEU B 67  ? HIS B 77  ? LEU B 102 HIS B 112 1 ? 11 
HELX_P HELX_P16 AB7 ASP B 92  ? LYS B 110 ? ASP B 127 LYS B 145 1 ? 19 
HELX_P HELX_P17 AB8 PRO B 112 ? ARG B 118 ? PRO B 147 ARG B 153 1 ? 7  
HELX_P HELX_P18 AB9 SER B 130 ? ASP B 143 ? SER B 165 ASP B 178 1 ? 14 
HELX_P HELX_P19 AC1 HIS B 183 ? ASN B 190 ? HIS B 218 ASN B 225 1 ? 8  
HELX_P HELX_P20 AC2 ILE B 208 ? SER B 212 ? ILE B 243 SER B 247 5 ? 5  
HELX_P HELX_P21 AC3 ASN B 214 ? CYS B 230 ? ASN B 249 CYS B 265 1 ? 17 
HELX_P HELX_P22 AC4 ASP B 232 ? LEU B 239 ? ASP B 267 LEU B 274 5 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 203 SG ? ? ? 1_555 A CYS 248 SG A ? A CYS 238 A CYS 283 1_555 ? ? ? ? ? ? ? 2.057 ? ? 
disulf2 disulf ? ? A CYS 240 SG ? ? ? 1_555 A CYS 257 SG ? ? A CYS 275 A CYS 292 1_555 ? ? ? ? ? ? ? 2.002 ? ? 
disulf3 disulf ? ? B CYS 203 SG ? ? ? 1_555 B CYS 248 SG A ? B CYS 238 B CYS 283 1_555 ? ? ? ? ? ? ? 2.062 ? ? 
disulf4 disulf ? ? B CYS 240 SG ? ? ? 1_555 B CYS 257 SG ? ? B CYS 275 B CYS 292 1_555 ? ? ? ? ? ? ? 2.073 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 203 ? CYS A 248 A CYS A 238 ? 1_555 CYS A 283 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 240 ? CYS A 257 ? CYS A 275 ? 1_555 CYS A 292 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 203 ? CYS B 248 A CYS B 238 ? 1_555 CYS B 283 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 240 ? CYS B 257 ? CYS B 275 ? 1_555 CYS B 292 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 3 ? 
AA3 ? 6 ? 
AA4 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 23  ? VAL A 28  ? VAL A 58  VAL A 63  
AA1 2 GLY A 39  ? PRO A 44  ? GLY A 74  PRO A 79  
AA1 3 VAL A 80  ? LEU A 84  ? VAL A 115 LEU A 119 
AA1 4 PHE A 51  ? ALA A 57  ? PHE A 86  ALA A 92  
AA1 5 LEU A 119 ? HIS A 129 ? LEU A 154 HIS A 164 
AA1 6 ALA A 148 ? LEU A 152 ? ALA A 183 LEU A 187 
AA2 1 VAL A 167 ? ALA A 172 ? VAL A 202 ALA A 207 
AA2 2 LYS A 197 ? LEU A 202 ? LYS A 232 LEU A 237 
AA2 3 LEU A 247 ? ASN A 253 ? LEU A 282 ASN A 288 
AA3 1 GLU B 22  ? VAL B 28  ? GLU B 57  VAL B 63  
AA3 2 GLY B 39  ? VAL B 45  ? GLY B 74  VAL B 80  
AA3 3 VAL B 80  ? LEU B 84  ? VAL B 115 LEU B 119 
AA3 4 PHE B 51  ? ALA B 57  ? PHE B 86  ALA B 92  
AA3 5 LEU B 119 ? HIS B 129 ? LEU B 154 HIS B 164 
AA3 6 ALA B 148 ? LEU B 152 ? ALA B 183 LEU B 187 
AA4 1 VAL B 167 ? ALA B 172 ? VAL B 202 ALA B 207 
AA4 2 LYS B 197 ? LEU B 202 ? LYS B 232 LEU B 237 
AA4 3 LEU B 247 ? ASN B 253 ? LEU B 282 ASN B 288 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 24  ? N GLY A 59  O TYR A 43  ? O TYR A 78  
AA1 2 3 N TYR A 42  ? N TYR A 77  O VAL A 81  ? O VAL A 116 
AA1 3 4 O PHE A 82  ? O PHE A 117 N ILE A 54  ? N ILE A 89  
AA1 4 5 N PHE A 51  ? N PHE A 86  O ASP A 120 ? O ASP A 155 
AA1 5 6 N GLY A 128 ? N GLY A 163 O LEU A 152 ? O LEU A 187 
AA2 1 2 N GLY A 171 ? N GLY A 206 O LEU A 202 ? O LEU A 237 
AA2 2 3 N TYR A 199 ? N TYR A 234 O LYS A 251 ? O LYS A 286 
AA3 1 2 N GLY B 24  ? N GLY B 59  O TYR B 43  ? O TYR B 78  
AA3 2 3 N TYR B 42  ? N TYR B 77  O VAL B 81  ? O VAL B 116 
AA3 3 4 O PHE B 82  ? O PHE B 117 N ILE B 54  ? N ILE B 89  
AA3 4 5 N PHE B 51  ? N PHE B 86  O ASP B 120 ? O ASP B 155 
AA3 5 6 N GLY B 128 ? N GLY B 163 O LEU B 152 ? O LEU B 187 
AA4 1 2 N GLY B 171 ? N GLY B 206 O LEU B 202 ? O LEU B 237 
AA4 2 3 N TYR B 199 ? N TYR B 234 O LYS B 251 ? O LYS B 286 
# 
_pdbx_entry_details.entry_id                   9JQW 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 O  A HOH 508 ? ? O B HOH 531 ? ? 1.85 
2  1 O  B HOH 535 ? ? O B HOH 556 ? ? 1.90 
3  1 O  A HOH 608 ? ? O A HOH 642 ? ? 2.05 
4  1 O  B HOH 407 ? ? O B HOH 415 ? ? 2.05 
5  1 O  B HOH 428 ? ? O B HOH 583 ? ? 2.08 
6  1 O  B HOH 539 ? ? O B HOH 611 ? ? 2.09 
7  1 O  B HOH 458 ? ? O B HOH 599 ? ? 2.11 
8  1 O2 B SO4 301 ? ? O B HOH 401 ? ? 2.11 
9  1 O  A HOH 569 ? ? O A HOH 572 ? ? 2.12 
10 1 O  A HOH 450 ? ? O A HOH 623 ? ? 2.18 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     483 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    B 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     410 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   4_445 
_pdbx_validate_symm_contact.dist              2.09 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 165 ? ? 66.38   -120.16 
2 1 THR A 188 ? ? 33.99   57.72   
3 1 HIS A 218 ? ? -120.42 -89.05  
4 1 PRO B 43  ? ? -77.91  -167.03 
5 1 ASP B 126 ? ? -146.42 10.37   
6 1 SER B 165 ? ? 65.35   -121.94 
7 1 THR B 188 ? ? 33.40   58.19   
8 1 HIS B 218 ? ? -122.41 -90.65  
9 1 ASN B 289 ? ? 71.37   33.43   
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A SER 36  ? A SER 1   
2 1 Y 1 A ASN 37  ? A ASN 2   
3 1 Y 1 A PRO 38  ? A PRO 3   
4 1 Y 1 A TYR 39  ? A TYR 4   
5 1 Y 1 B SER 36  ? B SER 1   
6 1 Y 1 B ASN 37  ? B ASN 2   
7 1 Y 1 B PRO 38  ? B PRO 3   
8 1 Y 1 B TYR 39  ? B TYR 4   
9 1 Y 1 B SER 293 ? B SER 258 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EDO C1   C N N 88  
EDO O1   O N N 89  
EDO C2   C N N 90  
EDO O2   O N N 91  
EDO H11  H N N 92  
EDO H12  H N N 93  
EDO HO1  H N N 94  
EDO H21  H N N 95  
EDO H22  H N N 96  
EDO HO2  H N N 97  
GLN N    N N N 98  
GLN CA   C N S 99  
GLN C    C N N 100 
GLN O    O N N 101 
GLN CB   C N N 102 
GLN CG   C N N 103 
GLN CD   C N N 104 
GLN OE1  O N N 105 
GLN NE2  N N N 106 
GLN OXT  O N N 107 
GLN H    H N N 108 
GLN H2   H N N 109 
GLN HA   H N N 110 
GLN HB2  H N N 111 
GLN HB3  H N N 112 
GLN HG2  H N N 113 
GLN HG3  H N N 114 
GLN HE21 H N N 115 
GLN HE22 H N N 116 
GLN HXT  H N N 117 
GLU N    N N N 118 
GLU CA   C N S 119 
GLU C    C N N 120 
GLU O    O N N 121 
GLU CB   C N N 122 
GLU CG   C N N 123 
GLU CD   C N N 124 
GLU OE1  O N N 125 
GLU OE2  O N N 126 
GLU OXT  O N N 127 
GLU H    H N N 128 
GLU H2   H N N 129 
GLU HA   H N N 130 
GLU HB2  H N N 131 
GLU HB3  H N N 132 
GLU HG2  H N N 133 
GLU HG3  H N N 134 
GLU HE2  H N N 135 
GLU HXT  H N N 136 
GLY N    N N N 137 
GLY CA   C N N 138 
GLY C    C N N 139 
GLY O    O N N 140 
GLY OXT  O N N 141 
GLY H    H N N 142 
GLY H2   H N N 143 
GLY HA2  H N N 144 
GLY HA3  H N N 145 
GLY HXT  H N N 146 
GOL C1   C N N 147 
GOL O1   O N N 148 
GOL C2   C N N 149 
GOL O2   O N N 150 
GOL C3   C N N 151 
GOL O3   O N N 152 
GOL H11  H N N 153 
GOL H12  H N N 154 
GOL HO1  H N N 155 
GOL H2   H N N 156 
GOL HO2  H N N 157 
GOL H31  H N N 158 
GOL H32  H N N 159 
GOL HO3  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
HOH O    O N N 182 
HOH H1   H N N 183 
HOH H2   H N N 184 
ILE N    N N N 185 
ILE CA   C N S 186 
ILE C    C N N 187 
ILE O    O N N 188 
ILE CB   C N S 189 
ILE CG1  C N N 190 
ILE CG2  C N N 191 
ILE CD1  C N N 192 
ILE OXT  O N N 193 
ILE H    H N N 194 
ILE H2   H N N 195 
ILE HA   H N N 196 
ILE HB   H N N 197 
ILE HG12 H N N 198 
ILE HG13 H N N 199 
ILE HG21 H N N 200 
ILE HG22 H N N 201 
ILE HG23 H N N 202 
ILE HD11 H N N 203 
ILE HD12 H N N 204 
ILE HD13 H N N 205 
ILE HXT  H N N 206 
LEU N    N N N 207 
LEU CA   C N S 208 
LEU C    C N N 209 
LEU O    O N N 210 
LEU CB   C N N 211 
LEU CG   C N N 212 
LEU CD1  C N N 213 
LEU CD2  C N N 214 
LEU OXT  O N N 215 
LEU H    H N N 216 
LEU H2   H N N 217 
LEU HA   H N N 218 
LEU HB2  H N N 219 
LEU HB3  H N N 220 
LEU HG   H N N 221 
LEU HD11 H N N 222 
LEU HD12 H N N 223 
LEU HD13 H N N 224 
LEU HD21 H N N 225 
LEU HD22 H N N 226 
LEU HD23 H N N 227 
LEU HXT  H N N 228 
LYS N    N N N 229 
LYS CA   C N S 230 
LYS C    C N N 231 
LYS O    O N N 232 
LYS CB   C N N 233 
LYS CG   C N N 234 
LYS CD   C N N 235 
LYS CE   C N N 236 
LYS NZ   N N N 237 
LYS OXT  O N N 238 
LYS H    H N N 239 
LYS H2   H N N 240 
LYS HA   H N N 241 
LYS HB2  H N N 242 
LYS HB3  H N N 243 
LYS HG2  H N N 244 
LYS HG3  H N N 245 
LYS HD2  H N N 246 
LYS HD3  H N N 247 
LYS HE2  H N N 248 
LYS HE3  H N N 249 
LYS HZ1  H N N 250 
LYS HZ2  H N N 251 
LYS HZ3  H N N 252 
LYS HXT  H N N 253 
MET N    N N N 254 
MET CA   C N S 255 
MET C    C N N 256 
MET O    O N N 257 
MET CB   C N N 258 
MET CG   C N N 259 
MET SD   S N N 260 
MET CE   C N N 261 
MET OXT  O N N 262 
MET H    H N N 263 
MET H2   H N N 264 
MET HA   H N N 265 
MET HB2  H N N 266 
MET HB3  H N N 267 
MET HG2  H N N 268 
MET HG3  H N N 269 
MET HE1  H N N 270 
MET HE2  H N N 271 
MET HE3  H N N 272 
MET HXT  H N N 273 
PHE N    N N N 274 
PHE CA   C N S 275 
PHE C    C N N 276 
PHE O    O N N 277 
PHE CB   C N N 278 
PHE CG   C Y N 279 
PHE CD1  C Y N 280 
PHE CD2  C Y N 281 
PHE CE1  C Y N 282 
PHE CE2  C Y N 283 
PHE CZ   C Y N 284 
PHE OXT  O N N 285 
PHE H    H N N 286 
PHE H2   H N N 287 
PHE HA   H N N 288 
PHE HB2  H N N 289 
PHE HB3  H N N 290 
PHE HD1  H N N 291 
PHE HD2  H N N 292 
PHE HE1  H N N 293 
PHE HE2  H N N 294 
PHE HZ   H N N 295 
PHE HXT  H N N 296 
PRO N    N N N 297 
PRO CA   C N S 298 
PRO C    C N N 299 
PRO O    O N N 300 
PRO CB   C N N 301 
PRO CG   C N N 302 
PRO CD   C N N 303 
PRO OXT  O N N 304 
PRO H    H N N 305 
PRO HA   H N N 306 
PRO HB2  H N N 307 
PRO HB3  H N N 308 
PRO HG2  H N N 309 
PRO HG3  H N N 310 
PRO HD2  H N N 311 
PRO HD3  H N N 312 
PRO HXT  H N N 313 
SER N    N N N 314 
SER CA   C N S 315 
SER C    C N N 316 
SER O    O N N 317 
SER CB   C N N 318 
SER OG   O N N 319 
SER OXT  O N N 320 
SER H    H N N 321 
SER H2   H N N 322 
SER HA   H N N 323 
SER HB2  H N N 324 
SER HB3  H N N 325 
SER HG   H N N 326 
SER HXT  H N N 327 
SO4 S    S N N 328 
SO4 O1   O N N 329 
SO4 O2   O N N 330 
SO4 O3   O N N 331 
SO4 O4   O N N 332 
THR N    N N N 333 
THR CA   C N S 334 
THR C    C N N 335 
THR O    O N N 336 
THR CB   C N R 337 
THR OG1  O N N 338 
THR CG2  C N N 339 
THR OXT  O N N 340 
THR H    H N N 341 
THR H2   H N N 342 
THR HA   H N N 343 
THR HB   H N N 344 
THR HG1  H N N 345 
THR HG21 H N N 346 
THR HG22 H N N 347 
THR HG23 H N N 348 
THR HXT  H N N 349 
TRP N    N N N 350 
TRP CA   C N S 351 
TRP C    C N N 352 
TRP O    O N N 353 
TRP CB   C N N 354 
TRP CG   C Y N 355 
TRP CD1  C Y N 356 
TRP CD2  C Y N 357 
TRP NE1  N Y N 358 
TRP CE2  C Y N 359 
TRP CE3  C Y N 360 
TRP CZ2  C Y N 361 
TRP CZ3  C Y N 362 
TRP CH2  C Y N 363 
TRP OXT  O N N 364 
TRP H    H N N 365 
TRP H2   H N N 366 
TRP HA   H N N 367 
TRP HB2  H N N 368 
TRP HB3  H N N 369 
TRP HD1  H N N 370 
TRP HE1  H N N 371 
TRP HE3  H N N 372 
TRP HZ2  H N N 373 
TRP HZ3  H N N 374 
TRP HH2  H N N 375 
TRP HXT  H N N 376 
TYR N    N N N 377 
TYR CA   C N S 378 
TYR C    C N N 379 
TYR O    O N N 380 
TYR CB   C N N 381 
TYR CG   C Y N 382 
TYR CD1  C Y N 383 
TYR CD2  C Y N 384 
TYR CE1  C Y N 385 
TYR CE2  C Y N 386 
TYR CZ   C Y N 387 
TYR OH   O N N 388 
TYR OXT  O N N 389 
TYR H    H N N 390 
TYR H2   H N N 391 
TYR HA   H N N 392 
TYR HB2  H N N 393 
TYR HB3  H N N 394 
TYR HD1  H N N 395 
TYR HD2  H N N 396 
TYR HE1  H N N 397 
TYR HE2  H N N 398 
TYR HH   H N N 399 
TYR HXT  H N N 400 
VAL N    N N N 401 
VAL CA   C N S 402 
VAL C    C N N 403 
VAL O    O N N 404 
VAL CB   C N N 405 
VAL CG1  C N N 406 
VAL CG2  C N N 407 
VAL OXT  O N N 408 
VAL H    H N N 409 
VAL H2   H N N 410 
VAL HA   H N N 411 
VAL HB   H N N 412 
VAL HG11 H N N 413 
VAL HG12 H N N 414 
VAL HG13 H N N 415 
VAL HG21 H N N 416 
VAL HG22 H N N 417 
VAL HG23 H N N 418 
VAL HXT  H N N 419 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
GOL C1  O1   sing N N 138 
GOL C1  C2   sing N N 139 
GOL C1  H11  sing N N 140 
GOL C1  H12  sing N N 141 
GOL O1  HO1  sing N N 142 
GOL C2  O2   sing N N 143 
GOL C2  C3   sing N N 144 
GOL C2  H2   sing N N 145 
GOL O2  HO2  sing N N 146 
GOL C3  O3   sing N N 147 
GOL C3  H31  sing N N 148 
GOL C3  H32  sing N N 149 
GOL O3  HO3  sing N N 150 
HIS N   CA   sing N N 151 
HIS N   H    sing N N 152 
HIS N   H2   sing N N 153 
HIS CA  C    sing N N 154 
HIS CA  CB   sing N N 155 
HIS CA  HA   sing N N 156 
HIS C   O    doub N N 157 
HIS C   OXT  sing N N 158 
HIS CB  CG   sing N N 159 
HIS CB  HB2  sing N N 160 
HIS CB  HB3  sing N N 161 
HIS CG  ND1  sing Y N 162 
HIS CG  CD2  doub Y N 163 
HIS ND1 CE1  doub Y N 164 
HIS ND1 HD1  sing N N 165 
HIS CD2 NE2  sing Y N 166 
HIS CD2 HD2  sing N N 167 
HIS CE1 NE2  sing Y N 168 
HIS CE1 HE1  sing N N 169 
HIS NE2 HE2  sing N N 170 
HIS OXT HXT  sing N N 171 
HOH O   H1   sing N N 172 
HOH O   H2   sing N N 173 
ILE N   CA   sing N N 174 
ILE N   H    sing N N 175 
ILE N   H2   sing N N 176 
ILE CA  C    sing N N 177 
ILE CA  CB   sing N N 178 
ILE CA  HA   sing N N 179 
ILE C   O    doub N N 180 
ILE C   OXT  sing N N 181 
ILE CB  CG1  sing N N 182 
ILE CB  CG2  sing N N 183 
ILE CB  HB   sing N N 184 
ILE CG1 CD1  sing N N 185 
ILE CG1 HG12 sing N N 186 
ILE CG1 HG13 sing N N 187 
ILE CG2 HG21 sing N N 188 
ILE CG2 HG22 sing N N 189 
ILE CG2 HG23 sing N N 190 
ILE CD1 HD11 sing N N 191 
ILE CD1 HD12 sing N N 192 
ILE CD1 HD13 sing N N 193 
ILE OXT HXT  sing N N 194 
LEU N   CA   sing N N 195 
LEU N   H    sing N N 196 
LEU N   H2   sing N N 197 
LEU CA  C    sing N N 198 
LEU CA  CB   sing N N 199 
LEU CA  HA   sing N N 200 
LEU C   O    doub N N 201 
LEU C   OXT  sing N N 202 
LEU CB  CG   sing N N 203 
LEU CB  HB2  sing N N 204 
LEU CB  HB3  sing N N 205 
LEU CG  CD1  sing N N 206 
LEU CG  CD2  sing N N 207 
LEU CG  HG   sing N N 208 
LEU CD1 HD11 sing N N 209 
LEU CD1 HD12 sing N N 210 
LEU CD1 HD13 sing N N 211 
LEU CD2 HD21 sing N N 212 
LEU CD2 HD22 sing N N 213 
LEU CD2 HD23 sing N N 214 
LEU OXT HXT  sing N N 215 
LYS N   CA   sing N N 216 
LYS N   H    sing N N 217 
LYS N   H2   sing N N 218 
LYS CA  C    sing N N 219 
LYS CA  CB   sing N N 220 
LYS CA  HA   sing N N 221 
LYS C   O    doub N N 222 
LYS C   OXT  sing N N 223 
LYS CB  CG   sing N N 224 
LYS CB  HB2  sing N N 225 
LYS CB  HB3  sing N N 226 
LYS CG  CD   sing N N 227 
LYS CG  HG2  sing N N 228 
LYS CG  HG3  sing N N 229 
LYS CD  CE   sing N N 230 
LYS CD  HD2  sing N N 231 
LYS CD  HD3  sing N N 232 
LYS CE  NZ   sing N N 233 
LYS CE  HE2  sing N N 234 
LYS CE  HE3  sing N N 235 
LYS NZ  HZ1  sing N N 236 
LYS NZ  HZ2  sing N N 237 
LYS NZ  HZ3  sing N N 238 
LYS OXT HXT  sing N N 239 
MET N   CA   sing N N 240 
MET N   H    sing N N 241 
MET N   H2   sing N N 242 
MET CA  C    sing N N 243 
MET CA  CB   sing N N 244 
MET CA  HA   sing N N 245 
MET C   O    doub N N 246 
MET C   OXT  sing N N 247 
MET CB  CG   sing N N 248 
MET CB  HB2  sing N N 249 
MET CB  HB3  sing N N 250 
MET CG  SD   sing N N 251 
MET CG  HG2  sing N N 252 
MET CG  HG3  sing N N 253 
MET SD  CE   sing N N 254 
MET CE  HE1  sing N N 255 
MET CE  HE2  sing N N 256 
MET CE  HE3  sing N N 257 
MET OXT HXT  sing N N 258 
PHE N   CA   sing N N 259 
PHE N   H    sing N N 260 
PHE N   H2   sing N N 261 
PHE CA  C    sing N N 262 
PHE CA  CB   sing N N 263 
PHE CA  HA   sing N N 264 
PHE C   O    doub N N 265 
PHE C   OXT  sing N N 266 
PHE CB  CG   sing N N 267 
PHE CB  HB2  sing N N 268 
PHE CB  HB3  sing N N 269 
PHE CG  CD1  doub Y N 270 
PHE CG  CD2  sing Y N 271 
PHE CD1 CE1  sing Y N 272 
PHE CD1 HD1  sing N N 273 
PHE CD2 CE2  doub Y N 274 
PHE CD2 HD2  sing N N 275 
PHE CE1 CZ   doub Y N 276 
PHE CE1 HE1  sing N N 277 
PHE CE2 CZ   sing Y N 278 
PHE CE2 HE2  sing N N 279 
PHE CZ  HZ   sing N N 280 
PHE OXT HXT  sing N N 281 
PRO N   CA   sing N N 282 
PRO N   CD   sing N N 283 
PRO N   H    sing N N 284 
PRO CA  C    sing N N 285 
PRO CA  CB   sing N N 286 
PRO CA  HA   sing N N 287 
PRO C   O    doub N N 288 
PRO C   OXT  sing N N 289 
PRO CB  CG   sing N N 290 
PRO CB  HB2  sing N N 291 
PRO CB  HB3  sing N N 292 
PRO CG  CD   sing N N 293 
PRO CG  HG2  sing N N 294 
PRO CG  HG3  sing N N 295 
PRO CD  HD2  sing N N 296 
PRO CD  HD3  sing N N 297 
PRO OXT HXT  sing N N 298 
SER N   CA   sing N N 299 
SER N   H    sing N N 300 
SER N   H2   sing N N 301 
SER CA  C    sing N N 302 
SER CA  CB   sing N N 303 
SER CA  HA   sing N N 304 
SER C   O    doub N N 305 
SER C   OXT  sing N N 306 
SER CB  OG   sing N N 307 
SER CB  HB2  sing N N 308 
SER CB  HB3  sing N N 309 
SER OG  HG   sing N N 310 
SER OXT HXT  sing N N 311 
SO4 S   O1   doub N N 312 
SO4 S   O2   doub N N 313 
SO4 S   O3   sing N N 314 
SO4 S   O4   sing N N 315 
THR N   CA   sing N N 316 
THR N   H    sing N N 317 
THR N   H2   sing N N 318 
THR CA  C    sing N N 319 
THR CA  CB   sing N N 320 
THR CA  HA   sing N N 321 
THR C   O    doub N N 322 
THR C   OXT  sing N N 323 
THR CB  OG1  sing N N 324 
THR CB  CG2  sing N N 325 
THR CB  HB   sing N N 326 
THR OG1 HG1  sing N N 327 
THR CG2 HG21 sing N N 328 
THR CG2 HG22 sing N N 329 
THR CG2 HG23 sing N N 330 
THR OXT HXT  sing N N 331 
TRP N   CA   sing N N 332 
TRP N   H    sing N N 333 
TRP N   H2   sing N N 334 
TRP CA  C    sing N N 335 
TRP CA  CB   sing N N 336 
TRP CA  HA   sing N N 337 
TRP C   O    doub N N 338 
TRP C   OXT  sing N N 339 
TRP CB  CG   sing N N 340 
TRP CB  HB2  sing N N 341 
TRP CB  HB3  sing N N 342 
TRP CG  CD1  doub Y N 343 
TRP CG  CD2  sing Y N 344 
TRP CD1 NE1  sing Y N 345 
TRP CD1 HD1  sing N N 346 
TRP CD2 CE2  doub Y N 347 
TRP CD2 CE3  sing Y N 348 
TRP NE1 CE2  sing Y N 349 
TRP NE1 HE1  sing N N 350 
TRP CE2 CZ2  sing Y N 351 
TRP CE3 CZ3  doub Y N 352 
TRP CE3 HE3  sing N N 353 
TRP CZ2 CH2  doub Y N 354 
TRP CZ2 HZ2  sing N N 355 
TRP CZ3 CH2  sing Y N 356 
TRP CZ3 HZ3  sing N N 357 
TRP CH2 HH2  sing N N 358 
TRP OXT HXT  sing N N 359 
TYR N   CA   sing N N 360 
TYR N   H    sing N N 361 
TYR N   H2   sing N N 362 
TYR CA  C    sing N N 363 
TYR CA  CB   sing N N 364 
TYR CA  HA   sing N N 365 
TYR C   O    doub N N 366 
TYR C   OXT  sing N N 367 
TYR CB  CG   sing N N 368 
TYR CB  HB2  sing N N 369 
TYR CB  HB3  sing N N 370 
TYR CG  CD1  doub Y N 371 
TYR CG  CD2  sing Y N 372 
TYR CD1 CE1  sing Y N 373 
TYR CD1 HD1  sing N N 374 
TYR CD2 CE2  doub Y N 375 
TYR CD2 HD2  sing N N 376 
TYR CE1 CZ   doub Y N 377 
TYR CE1 HE1  sing N N 378 
TYR CE2 CZ   sing Y N 379 
TYR CE2 HE2  sing N N 380 
TYR CZ  OH   sing N N 381 
TYR OH  HH   sing N N 382 
TYR OXT HXT  sing N N 383 
VAL N   CA   sing N N 384 
VAL N   H    sing N N 385 
VAL N   H2   sing N N 386 
VAL CA  C    sing N N 387 
VAL CA  CB   sing N N 388 
VAL CA  HA   sing N N 389 
VAL C   O    doub N N 390 
VAL C   OXT  sing N N 391 
VAL CB  CG1  sing N N 392 
VAL CB  CG2  sing N N 393 
VAL CB  HB   sing N N 394 
VAL CG1 HG11 sing N N 395 
VAL CG1 HG12 sing N N 396 
VAL CG1 HG13 sing N N 397 
VAL CG2 HG21 sing N N 398 
VAL CG2 HG22 sing N N 399 
VAL CG2 HG23 sing N N 400 
VAL OXT HXT  sing N N 401 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7vve 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9JQW 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.025246 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.013389 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006351 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.310  20.844 1.020 10.208 1.589 0.569  0.865 51.651 0.216   
H 1  1  0.493  10.511 0.323 26.126 0.140 3.142  0.041 57.800 0.003   
N 7  7  12.222 0.006  3.135 9.893  2.014 28.997 1.167 0.583  -11.538 
O 8  8  3.049  13.277 2.287 5.701  1.546 0.324  0.867 32.909 0.251   
S 16 16 6.905  1.468  5.203 22.215 1.438 0.254  1.586 56.172 1.050   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . LEU A 1 5   ? -15.594 -2.282  50.524  1.000 58.198 0 40  LEU A N   1 ? 
ATOM   2    C CA  . LEU A 1 5   ? -14.120 -2.490  50.512  1.000 52.043 0 40  LEU A CA  1 ? 
ATOM   3    C C   . LEU A 1 5   ? -13.742 -3.401  51.673  1.000 51.773 0 40  LEU A C   1 ? 
ATOM   4    O O   . LEU A 1 5   ? -13.393 -2.944  52.760  1.000 60.488 0 40  LEU A O   1 ? 
ATOM   5    C CB  . LEU A 1 5   ? -13.406 -1.139  50.562  1.000 49.774 0 40  LEU A CB  1 ? 
ATOM   6    C CG  . LEU A 1 5   ? -13.142 -0.525  49.190  1.000 49.612 0 40  LEU A CG  1 ? 
ATOM   7    C CD1 . LEU A 1 5   ? -14.376 -0.578  48.305  1.000 46.562 0 40  LEU A CD1 1 ? 
ATOM   8    C CD2 . LEU A 1 5   ? -12.658 0.902   49.341  1.000 53.070 0 40  LEU A CD2 1 ? 
ATOM   9    N N   . VAL A 1 6   ? -13.840 -4.707  51.413  1.000 47.965 0 41  VAL A N   1 ? 
ATOM   10   C CA  . VAL A 1 6   ? -13.594 -5.727  52.414  1.000 48.129 0 41  VAL A CA  1 ? 
ATOM   11   C C   . VAL A 1 6   ? -12.359 -6.525  51.992  1.000 43.346 0 41  VAL A C   1 ? 
ATOM   12   O O   . VAL A 1 6   ? -12.103 -6.714  50.804  1.000 40.141 0 41  VAL A O   1 ? 
ATOM   13   C CB  . VAL A 1 6   ? -14.854 -6.607  52.591  1.000 50.057 0 41  VAL A CB  1 ? 
ATOM   14   C CG1 . VAL A 1 6   ? -14.548 -8.041  53.012  1.000 54.643 0 41  VAL A CG1 1 ? 
ATOM   15   C CG2 . VAL A 1 6   ? -15.853 -5.955  53.546  1.000 49.572 0 41  VAL A CG2 1 ? 
ATOM   16   N N   . GLY A 1 7   ? -11.601 -6.994  52.988  1.000 38.439 0 42  GLY A N   1 ? 
ATOM   17   C CA  . GLY A 1 7   ? -10.486 -7.892  52.740  1.000 35.954 0 42  GLY A CA  1 ? 
ATOM   18   C C   . GLY A 1 7   ? -9.188  -7.137  52.441  1.000 30.831 0 42  GLY A C   1 ? 
ATOM   19   O O   . GLY A 1 7   ? -9.155  -5.903  52.438  1.000 26.243 0 42  GLY A O   1 ? 
ATOM   20   N N   . PRO A 1 8   ? -8.076  -7.870  52.200  1.000 27.235 0 43  PRO A N   1 ? 
ATOM   21   C CA  . PRO A 1 8   ? -6.752  -7.261  52.075  1.000 24.713 0 43  PRO A CA  1 ? 
ATOM   22   C C   . PRO A 1 8   ? -6.603  -6.383  50.833  1.000 23.196 0 43  PRO A C   1 ? 
ATOM   23   O O   . PRO A 1 8   ? -7.310  -6.552  49.837  1.000 19.601 0 43  PRO A O   1 ? 
ATOM   24   C CB  . PRO A 1 8   ? -5.812  -8.464  51.983  1.000 25.848 0 43  PRO A CB  1 ? 
ATOM   25   C CG  . PRO A 1 8   ? -6.614  -9.624  52.556  1.000 29.341 0 43  PRO A CG  1 ? 
ATOM   26   C CD  . PRO A 1 8   ? -8.029  -9.335  52.110  1.000 28.834 0 43  PRO A CD  1 ? 
ATOM   27   N N   . GLU A 1 9   ? -5.648  -5.454  50.909  1.000 21.634 0 44  GLU A N   1 ? 
ATOM   28   C CA  . GLU A 1 9   ? -5.285  -4.627  49.777  1.000 21.490 0 44  GLU A CA  1 ? 
ATOM   29   C C   . GLU A 1 9   ? -4.847  -5.526  48.622  1.000 20.013 0 44  GLU A C   1 ? 
ATOM   30   O O   . GLU A 1 9   ? -3.969  -6.370  48.780  1.000 19.052 0 44  GLU A O   1 ? 
ATOM   31   C CB  . GLU A 1 9   ? -4.154  -3.660  50.167  1.000 22.359 0 44  GLU A CB  1 ? 
ATOM   32   C CG  . GLU A 1 9   ? -3.863  -2.587  49.128  1.000 25.294 0 44  GLU A CG  1 ? 
ATOM   33   C CD  . GLU A 1 9   ? -4.950  -1.540  48.911  1.000 29.031 0 44  GLU A CD  1 ? 
ATOM   34   O OE1 . GLU A 1 9   ? -5.617  -1.139  49.916  1.000 30.203 0 44  GLU A OE1 1 ? 
ATOM   35   O OE2 . GLU A 1 9   ? -5.079  -1.055  47.747  1.000 31.609 0 44  GLU A OE2 1 ? 
ATOM   36   N N   . PRO A 1 10  ? -5.403  -5.361  47.402  1.000 19.303 0 45  PRO A N   1 ? 
ATOM   37   C CA  . PRO A 1 10  ? -4.878  -6.055  46.232  1.000 19.748 0 45  PRO A CA  1 ? 
ATOM   38   C C   . PRO A 1 10  ? -3.484  -5.575  45.848  1.000 21.490 0 45  PRO A C   1 ? 
ATOM   39   O O   . PRO A 1 10  ? -3.189  -4.380  45.952  1.000 18.760 0 45  PRO A O   1 ? 
ATOM   40   C CB  . PRO A 1 10  ? -5.877  -5.680  45.128  1.000 19.854 0 45  PRO A CB  1 ? 
ATOM   41   C CG  . PRO A 1 10  ? -6.390  -4.332  45.563  1.000 19.608 0 45  PRO A CG  1 ? 
ATOM   42   C CD  . PRO A 1 10  ? -6.523  -4.473  47.065  1.000 19.734 0 45  PRO A CD  1 ? 
ATOM   43   N N   . THR A 1 11  ? -2.663  -6.511  45.337  1.000 22.761 0 46  THR A N   1 ? 
ATOM   44   C CA  . THR A 1 11  ? -1.370  -6.168  44.756  1.000 22.879 0 46  THR A CA  1 ? 
ATOM   45   C C   . THR A 1 11  ? -1.256  -6.752  43.348  1.000 23.636 0 46  THR A C   1 ? 
ATOM   46   O O   . THR A 1 11  ? -2.010  -7.647  42.961  1.000 19.585 0 46  THR A O   1 ? 
ATOM   47   C CB  . THR A 1 11  ? -0.233  -6.689  45.642  1.000 21.692 0 46  THR A CB  1 ? 
ATOM   48   O OG1 . THR A 1 11  ? -0.230  -8.111  45.511  1.000 19.973 0 46  THR A OG1 1 ? 
ATOM   49   C CG2 . THR A 1 11  ? -0.384  -6.264  47.088  1.000 21.836 0 46  THR A CG2 1 ? 
ATOM   50   N N   . LEU A 1 12  ? -0.269  -6.261  42.605  1.000 23.059 0 47  LEU A N   1 ? 
ATOM   51   C CA  . LEU A 1 12  ? 0.044   -6.798  41.289  1.000 26.900 0 47  LEU A CA  1 ? 
ATOM   52   C C   . LEU A 1 12  ? 0.253   -8.318  41.362  1.000 26.479 0 47  LEU A C   1 ? 
ATOM   53   O O   . LEU A 1 12  ? -0.219  -9.073  40.511  1.000 25.896 0 47  LEU A O   1 ? 
ATOM   54   C CB  . LEU A 1 12  ? 1.291   -6.061  40.795  1.000 27.595 0 47  LEU A CB  1 ? 
ATOM   55   C CG  . LEU A 1 12  ? 1.408   -5.836  39.290  1.000 29.439 0 47  LEU A CG  1 ? 
ATOM   56   C CD1 . LEU A 1 12  ? 0.134   -5.264  38.690  1.000 27.136 0 47  LEU A CD1 1 ? 
ATOM   57   C CD2 . LEU A 1 12  ? 2.569   -4.899  39.019  1.000 29.440 0 47  LEU A CD2 1 ? 
ATOM   58   N N   . GLU A 1 13  ? 0.932   -8.764  42.421  1.000 27.324 0 48  GLU A N   1 ? 
ATOM   59   C CA  . GLU A 1 13  ? 1.247   -10.169 42.636  1.000 29.442 0 48  GLU A CA  1 ? 
ATOM   60   C C   . GLU A 1 13  ? -0.035  -10.969 42.913  1.000 26.792 0 48  GLU A C   1 ? 
ATOM   61   O O   . GLU A 1 13  ? -0.200  -12.070 42.388  1.000 26.714 0 48  GLU A O   1 ? 
ATOM   62   C CB  . GLU A 1 13  ? 2.231   -10.314 43.803  1.000 33.897 0 48  GLU A CB  1 ? 
ATOM   63   C CG  . GLU A 1 13  ? 3.581   -9.599  43.589  1.000 42.187 0 48  GLU A CG  1 ? 
ATOM   64   C CD  . GLU A 1 13  ? 3.601   -8.095  43.265  1.000 45.476 0 48  GLU A CD  1 ? 
ATOM   65   O OE1 . GLU A 1 13  ? 2.986   -7.268  44.036  1.000 39.455 0 48  GLU A OE1 1 ? 
ATOM   66   O OE2 . GLU A 1 13  ? 4.241   -7.731  42.230  1.000 44.354 0 48  GLU A OE2 1 ? 
ATOM   67   N N   . SER A 1 14  ? -0.947  -10.411 43.722  1.000 21.844 0 49  SER A N   1 ? 
ATOM   68   C CA  . SER A 1 14  ? -2.154  -11.121 44.124  1.000 21.527 0 49  SER A CA  1 ? 
ATOM   69   C C   . SER A 1 14  ? -3.128  -11.323 42.958  1.000 18.901 0 49  SER A C   1 ? 
ATOM   70   O O   . SER A 1 14  ? -3.858  -12.330 42.944  1.000 16.545 0 49  SER A O   1 ? 
ATOM   71   C CB  . SER A 1 14  ? -2.836  -10.451 45.309  1.000 22.229 0 49  SER A CB  1 ? 
ATOM   72   O OG  . SER A 1 14  ? -3.554  -9.280  44.934  1.000 23.200 0 49  SER A OG  1 ? 
ATOM   73   N N   . LEU A 1 15  ? -3.147  -10.368 42.012  1.000 18.585 0 50  LEU A N   1 ? 
ATOM   74   C CA  . LEU A 1 15  ? -4.029  -10.415 40.850  1.000 20.619 0 50  LEU A CA  1 ? 
ATOM   75   C C   . LEU A 1 15  ? -3.629  -11.559 39.921  1.000 20.607 0 50  LEU A C   1 ? 
ATOM   76   O O   . LEU A 1 15  ? -4.458  -12.069 39.179  1.000 20.048 0 50  LEU A O   1 ? 
ATOM   77   C CB  . LEU A 1 15  ? -3.954  -9.105  40.061  1.000 21.717 0 50  LEU A CB  1 ? 
ATOM   78   C CG  . LEU A 1 15  ? -4.447  -7.833  40.758  1.000 23.943 0 50  LEU A CG  1 ? 
ATOM   79   C CD1 . LEU A 1 15  ? -4.289  -6.636  39.848  1.000 25.497 0 50  LEU A CD1 1 ? 
ATOM   80   C CD2 . LEU A 1 15  ? -5.884  -7.946  41.195  1.000 24.865 0 50  LEU A CD2 1 ? 
ATOM   81   N N   . GLN A 1 16  ? -2.347  -11.938 39.930  1.000 20.593 0 51  GLN A N   1 ? 
ATOM   82   C CA  . GLN A 1 16  ? -1.856  -12.967 39.017  1.000 20.859 0 51  GLN A CA  1 ? 
ATOM   83   C C   . GLN A 1 16  ? -1.991  -14.372 39.604  1.000 21.152 0 51  GLN A C   1 ? 
ATOM   84   O O   . GLN A 1 16  ? -1.811  -15.370 38.904  1.000 22.102 0 51  GLN A O   1 ? 
ATOM   85   C CB  . GLN A 1 16  ? -0.385  -12.710 38.677  1.000 22.051 0 51  GLN A CB  1 ? 
ATOM   86   C CG  . GLN A 1 16  ? -0.161  -11.369 38.022  1.000 23.085 0 51  GLN A CG  1 ? 
ATOM   87   C CD  . GLN A 1 16  ? 1.300   -11.068 37.815  1.000 26.861 0 51  GLN A CD  1 ? 
ATOM   88   O OE1 . GLN A 1 16  ? 1.926   -11.621 36.907  1.000 27.903 0 51  GLN A OE1 1 ? 
ATOM   89   N NE2 . GLN A 1 16  ? 1.807   -10.123 38.599  1.000 24.494 0 51  GLN A NE2 1 ? 
ATOM   90   N N   . LYS A 1 17  ? -2.298  -14.490 40.887  1.000 21.152 0 52  LYS A N   1 ? 
ATOM   91   C CA  . LYS A 1 17  ? -2.530  -15.818 41.443  1.000 23.467 0 52  LYS A CA  1 ? 
ATOM   92   C C   . LYS A 1 17  ? -4.029  -16.031 41.640  1.000 21.021 0 52  LYS A C   1 ? 
ATOM   93   O O   . LYS A 1 17  ? -4.803  -15.077 41.573  1.000 19.701 0 52  LYS A O   1 ? 
ATOM   94   C CB  . LYS A 1 17  ? -1.828  -15.978 42.789  1.000 28.228 0 52  LYS A CB  1 ? 
ATOM   95   C CG  . LYS A 1 17  ? -0.328  -15.720 42.745  1.000 35.915 0 52  LYS A CG  1 ? 
ATOM   96   C CD  . LYS A 1 17  ? 0.348   -16.021 44.065  1.000 39.644 0 52  LYS A CD  1 ? 
ATOM   97   C CE  . LYS A 1 17  ? -0.173  -15.186 45.216  1.000 44.965 0 52  LYS A CE  1 ? 
ATOM   98   N NZ  . LYS A 1 17  ? -0.421  -16.024 46.416  1.000 49.922 0 52  LYS A NZ  1 ? 
ATOM   99   N N   . LEU A 1 18  ? -4.410  -17.279 41.937  1.000 19.908 0 53  LEU A N   1 ? 
ATOM   100  C CA  . LEU A 1 18  ? -5.778  -17.553 42.346  1.000 20.317 0 53  LEU A CA  1 ? 
ATOM   101  C C   . LEU A 1 18  ? -6.086  -16.649 43.543  1.000 18.796 0 53  LEU A C   1 ? 
ATOM   102  O O   . LEU A 1 18  ? -5.213  -16.356 44.352  1.000 19.294 0 53  LEU A O   1 ? 
ATOM   103  C CB  . LEU A 1 18  ? -5.943  -19.048 42.653  1.000 19.123 0 53  LEU A CB  1 ? 
ATOM   104  C CG  . LEU A 1 18  ? -5.777  -19.975 41.445  1.000 21.121 0 53  LEU A CG  1 ? 
ATOM   105  C CD1 . LEU A 1 18  ? -5.904  -21.432 41.857  1.000 20.482 0 53  LEU A CD1 1 ? 
ATOM   106  C CD2 . LEU A 1 18  ? -6.808  -19.646 40.368  1.000 21.520 0 53  LEU A CD2 1 ? 
ATOM   107  N N   . GLY A 1 19  ? -7.312  -16.126 43.578  1.000 18.303 0 54  GLY A N   1 ? 
ATOM   108  C CA  . GLY A 1 19  ? -7.777  -15.309 44.674  1.000 17.805 0 54  GLY A CA  1 ? 
ATOM   109  C C   . GLY A 1 19  ? -8.113  -16.189 45.875  1.000 19.660 0 54  GLY A C   1 ? 
ATOM   110  O O   . GLY A 1 19  ? -7.891  -17.393 45.855  1.000 17.803 0 54  GLY A O   1 ? 
ATOM   111  N N   . PRO A 1 20  ? -8.692  -15.608 46.940  1.000 18.941 0 55  PRO A N   1 ? 
ATOM   112  C CA  . PRO A 1 20  ? -8.898  -16.339 48.184  1.000 20.856 0 55  PRO A CA  1 ? 
ATOM   113  C C   . PRO A 1 20  ? -10.045 -17.352 48.199  1.000 22.694 0 55  PRO A C   1 ? 
ATOM   114  O O   . PRO A 1 20  ? -10.168 -18.087 49.165  1.000 21.202 0 55  PRO A O   1 ? 
ATOM   115  C CB  . PRO A 1 20  ? -9.222  -15.206 49.173  1.000 20.519 0 55  PRO A CB  1 ? 
ATOM   116  C CG  . PRO A 1 20  ? -9.882  -14.156 48.308  1.000 21.399 0 55  PRO A CG  1 ? 
ATOM   117  C CD  . PRO A 1 20  ? -9.123  -14.205 46.996  1.000 20.562 0 55  PRO A CD  1 ? 
ATOM   118  N N   . PHE A 1 21  ? -10.875 -17.403 47.145  1.000 22.084 0 56  PHE A N   1 ? 
ATOM   119  C CA  . PHE A 1 21  ? -11.994 -18.334 47.117  1.000 20.985 0 56  PHE A CA  1 ? 
ATOM   120  C C   . PHE A 1 21  ? -11.643 -19.601 46.343  1.000 21.956 0 56  PHE A C   1 ? 
ATOM   121  O O   . PHE A 1 21  ? -11.144 -19.560 45.215  1.000 19.607 0 56  PHE A O   1 ? 
ATOM   122  C CB  . PHE A 1 21  ? -13.241 -17.671 46.540  1.000 20.307 0 56  PHE A CB  1 ? 
ATOM   123  C CG  . PHE A 1 21  ? -13.690 -16.477 47.341  1.000 20.003 0 56  PHE A CG  1 ? 
ATOM   124  C CD1 . PHE A 1 21  ? -14.372 -16.640 48.537  1.000 20.288 0 56  PHE A CD1 1 ? 
ATOM   125  C CD2 . PHE A 1 21  ? -13.408 -15.192 46.906  1.000 21.113 0 56  PHE A CD2 1 ? 
ATOM   126  C CE1 . PHE A 1 21  ? -14.807 -15.533 49.259  1.000 21.064 0 56  PHE A CE1 1 ? 
ATOM   127  C CE2 . PHE A 1 21  ? -13.820 -14.085 47.642  1.000 20.592 0 56  PHE A CE2 1 ? 
ATOM   128  C CZ  . PHE A 1 21  ? -14.521 -14.257 48.816  1.000 20.757 0 56  PHE A CZ  1 ? 
ATOM   129  N N   . GLU A 1 22  ? -11.920 -20.722 47.012  1.000 22.107 0 57  GLU A N   1 ? 
ATOM   130  C CA  . GLU A 1 22  ? -12.036 -22.019 46.377  1.000 24.054 0 57  GLU A CA  1 ? 
ATOM   131  C C   . GLU A 1 22  ? -13.197 -21.948 45.392  1.000 21.957 0 57  GLU A C   1 ? 
ATOM   132  O O   . GLU A 1 22  ? -14.183 -21.250 45.644  1.000 18.245 0 57  GLU A O   1 ? 
ATOM   133  C CB  . GLU A 1 22  ? -12.220 -23.065 47.475  1.000 28.903 0 57  GLU A CB  1 ? 
ATOM   134  C CG  . GLU A 1 22  ? -12.376 -24.492 47.004  1.000 36.751 0 57  GLU A CG  1 ? 
ATOM   135  C CD  . GLU A 1 22  ? -12.405 -25.475 48.167  1.000 43.389 0 57  GLU A CD  1 ? 
ATOM   136  O OE1 . GLU A 1 22  ? -12.194 -25.039 49.343  1.000 40.784 0 57  GLU A OE1 1 ? 
ATOM   137  O OE2 . GLU A 1 22  ? -12.644 -26.672 47.892  1.000 51.132 0 57  GLU A OE2 1 ? 
ATOM   138  N N   . VAL A 1 23  ? -13.071 -22.704 44.296  1.000 19.919 0 58  VAL A N   1 ? 
ATOM   139  C CA  . VAL A 1 23  ? -14.001 -22.634 43.188  1.000 21.347 0 58  VAL A CA  1 ? 
ATOM   140  C C   . VAL A 1 23  ? -14.682 -23.986 43.010  1.000 20.842 0 58  VAL A C   1 ? 
ATOM   141  O O   . VAL A 1 23  ? -14.014 -25.012 43.003  1.000 21.532 0 58  VAL A O   1 ? 
ATOM   142  C CB  . VAL A 1 23  ? -13.269 -22.182 41.905  1.000 22.300 0 58  VAL A CB  1 ? 
ATOM   143  C CG1 . VAL A 1 23  ? -14.156 -22.266 40.665  1.000 20.991 0 58  VAL A CG1 1 ? 
ATOM   144  C CG2 . VAL A 1 23  ? -12.706 -20.777 42.103  1.000 21.730 0 58  VAL A CG2 1 ? 
ATOM   145  N N   . GLY A 1 24  ? -16.016 -23.959 42.924  1.000 18.999 0 59  GLY A N   1 ? 
ATOM   146  C CA  . GLY A 1 24  ? -16.806 -25.084 42.463  1.000 18.006 0 59  GLY A CA  1 ? 
ATOM   147  C C   . GLY A 1 24  ? -17.327 -24.824 41.055  1.000 17.575 0 59  GLY A C   1 ? 
ATOM   148  O O   . GLY A 1 24  ? -17.278 -23.689 40.579  1.000 15.668 0 59  GLY A O   1 ? 
ATOM   149  N N   . THR A 1 25  ? -17.788 -25.889 40.386  1.000 17.451 0 60  THR A N   1 ? 
ATOM   150  C CA  . THR A 1 25  ? -18.391 -25.756 39.066  1.000 19.283 0 60  THR A CA  1 ? 
ATOM   151  C C   . THR A 1 25  ? -19.734 -26.481 39.006  1.000 19.150 0 60  THR A C   1 ? 
ATOM   152  O O   . THR A 1 25  ? -19.929 -27.510 39.649  1.000 17.310 0 60  THR A O   1 ? 
ATOM   153  C CB  . THR A 1 25  ? -17.488 -26.288 37.941  1.000 19.172 0 60  THR A CB  1 ? 
ATOM   154  O OG1 . THR A 1 25  ? -17.340 -27.680 38.203  1.000 21.222 0 60  THR A OG1 1 ? 
ATOM   155  C CG2 . THR A 1 25  ? -16.146 -25.585 37.845  1.000 19.102 0 60  THR A CG2 1 ? 
ATOM   156  N N   . TYR A 1 26  ? -20.650 -25.934 38.191  1.000 19.844 0 61  TYR A N   1 ? 
ATOM   157  C CA  . TYR A 1 26  ? -21.863 -26.632 37.791  1.000 19.342 0 61  TYR A CA  1 ? 
ATOM   158  C C   . TYR A 1 26  ? -21.880 -26.645 36.261  1.000 19.162 0 61  TYR A C   1 ? 
ATOM   159  O O   . TYR A 1 26  ? -21.751 -25.593 35.636  1.000 17.555 0 61  TYR A O   1 ? 
ATOM   160  C CB  . TYR A 1 26  ? -23.115 -25.981 38.385  1.000 19.555 0 61  TYR A CB  1 ? 
ATOM   161  C CG  . TYR A 1 26  ? -24.399 -26.565 37.849  1.000 19.380 0 61  TYR A CG  1 ? 
ATOM   162  C CD1 . TYR A 1 26  ? -24.837 -27.822 38.229  1.000 20.648 0 61  TYR A CD1 1 ? 
ATOM   163  C CD2 . TYR A 1 26  ? -25.120 -25.909 36.870  1.000 21.163 0 61  TYR A CD2 1 ? 
ATOM   164  C CE1 . TYR A 1 26  ? -25.974 -28.397 37.683  1.000 20.914 0 61  TYR A CE1 1 ? 
ATOM   165  C CE2 . TYR A 1 26  ? -26.286 -26.452 36.332  1.000 21.854 0 61  TYR A CE2 1 ? 
ATOM   166  C CZ  . TYR A 1 26  ? -26.692 -27.715 36.717  1.000 22.429 0 61  TYR A CZ  1 ? 
ATOM   167  O OH  . TYR A 1 26  ? -27.789 -28.295 36.158  1.000 22.446 0 61  TYR A OH  1 ? 
ATOM   168  N N   . THR A 1 27  ? -21.984 -27.851 35.681  1.000 18.198 0 62  THR A N   1 ? 
ATOM   169  C CA  . THR A 1 27  ? -22.068 -28.015 34.243  1.000 18.756 0 62  THR A CA  1 ? 
ATOM   170  C C   . THR A 1 27  ? -23.532 -27.964 33.818  1.000 19.787 0 62  THR A C   1 ? 
ATOM   171  O O   . THR A 1 27  ? -24.361 -28.717 34.320  1.000 20.478 0 62  THR A O   1 ? 
ATOM   172  C CB  . THR A 1 27  ? -21.318 -29.260 33.769  1.000 19.345 0 62  THR A CB  1 ? 
ATOM   173  O OG1 . THR A 1 27  ? -19.943 -29.022 34.069  1.000 19.807 0 62  THR A OG1 1 ? 
ATOM   174  C CG2 . THR A 1 27  ? -21.442 -29.506 32.283  1.000 20.896 0 62  THR A CG2 1 ? 
ATOM   175  N N   . VAL A 1 28  ? -23.826 -27.036 32.899  1.000 19.695 0 63  VAL A N   1 ? 
ATOM   176  C CA  . VAL A 1 28  ? -25.160 -26.790 32.393  1.000 20.942 0 63  VAL A CA  1 ? 
ATOM   177  C C   . VAL A 1 28  ? -25.310 -27.574 31.092  1.000 20.905 0 63  VAL A C   1 ? 
ATOM   178  O O   . VAL A 1 28  ? -24.761 -27.180 30.067  1.000 20.909 0 63  VAL A O   1 ? 
ATOM   179  C CB  . VAL A 1 28  ? -25.407 -25.285 32.159  1.000 21.162 0 63  VAL A CB  1 ? 
ATOM   180  C CG1 . VAL A 1 28  ? -26.773 -25.020 31.548  1.000 22.336 0 63  VAL A CG1 1 ? 
ATOM   181  C CG2 . VAL A 1 28  ? -25.243 -24.468 33.434  1.000 22.338 0 63  VAL A CG2 1 ? 
ATOM   182  N N   . PRO A 1 29  ? -26.103 -28.672 31.060  1.000 21.590 0 64  PRO A N   1 ? 
ATOM   183  C CA  . PRO A 1 29  ? -26.342 -29.386 29.809  1.000 21.334 0 64  PRO A CA  1 ? 
ATOM   184  C C   . PRO A 1 29  ? -27.056 -28.509 28.779  1.000 19.622 0 64  PRO A C   1 ? 
ATOM   185  O O   . PRO A 1 29  ? -27.914 -27.693 29.122  1.000 17.698 0 64  PRO A O   1 ? 
ATOM   186  C CB  . PRO A 1 29  ? -27.244 -30.559 30.214  1.000 23.186 0 64  PRO A CB  1 ? 
ATOM   187  C CG  . PRO A 1 29  ? -27.139 -30.655 31.729  1.000 23.607 0 64  PRO A CG  1 ? 
ATOM   188  C CD  . PRO A 1 29  ? -26.874 -29.230 32.184  1.000 23.177 0 64  PRO A CD  1 ? 
ATOM   189  N N   . ALA A 1 30  ? -26.708 -28.721 27.508  1.000 20.027 0 65  ALA A N   1 ? 
ATOM   190  C CA  . ALA A 1 30  ? -27.374 -28.075 26.389  1.000 20.521 0 65  ALA A CA  1 ? 
ATOM   191  C C   . ALA A 1 30  ? -28.888 -28.293 26.457  1.000 21.280 0 65  ALA A C   1 ? 
ATOM   192  O O   . ALA A 1 30  ? -29.647 -27.403 26.092  1.000 20.475 0 65  ALA A O   1 ? 
ATOM   193  C CB  . ALA A 1 30  ? -26.790 -28.617 25.097  1.000 19.912 0 65  ALA A CB  1 ? 
ATOM   194  N N   . SER A 1 31  ? -29.326 -29.483 26.905  1.000 23.501 0 66  SER A N   1 ? 
ATOM   195  C CA  . SER A 1 31  ? -30.745 -29.846 26.913  1.000 24.598 0 66  SER A CA  1 ? 
ATOM   196  C C   . SER A 1 31  ? -31.543 -29.063 27.944  1.000 23.678 0 66  SER A C   1 ? 
ATOM   197  O O   . SER A 1 31  ? -32.768 -29.060 27.871  1.000 25.541 0 66  SER A O   1 ? 
ATOM   198  C CB  . SER A 1 31  ? -30.945 -31.317 27.152  1.000 25.578 0 66  SER A CB  1 ? 
ATOM   199  O OG  . SER A 1 31  ? -30.230 -31.733 28.303  1.000 28.257 0 66  SER A OG  1 ? 
ATOM   200  N N   . SER A 1 32  ? -30.871 -28.403 28.898  1.000 23.409 0 67  SER A N   1 ? 
ATOM   201  C CA  . SER A 1 32  ? -31.582 -27.773 30.003  1.000 25.421 0 67  SER A CA  1 ? 
ATOM   202  C C   . SER A 1 32  ? -31.840 -26.291 29.734  1.000 24.463 0 67  SER A C   1 ? 
ATOM   203  O O   . SER A 1 32  ? -32.484 -25.651 30.546  1.000 26.305 0 67  SER A O   1 ? 
ATOM   204  C CB  . SER A 1 32  ? -30.853 -27.982 31.302  1.000 25.433 0 67  SER A CB  1 ? 
ATOM   205  O OG  . SER A 1 32  ? -29.623 -27.276 31.287  1.000 33.743 0 67  SER A OG  1 ? 
ATOM   206  N N   . VAL A 1 33  ? -31.365 -25.760 28.593  1.000 23.666 0 68  VAL A N   1 ? 
ATOM   207  C CA  . VAL A 1 33  ? -31.413 -24.334 28.317  1.000 23.932 0 68  VAL A CA  1 ? 
ATOM   208  C C   . VAL A 1 33  ? -31.806 -24.088 26.864  1.000 23.429 0 68  VAL A C   1 ? 
ATOM   209  O O   . VAL A 1 33  ? -31.632 -24.944 26.002  1.000 25.389 0 68  VAL A O   1 ? 
ATOM   210  C CB  . VAL A 1 33  ? -30.058 -23.647 28.627  1.000 24.626 0 68  VAL A CB  1 ? 
ATOM   211  C CG1 . VAL A 1 33  ? -29.694 -23.712 30.098  1.000 25.777 0 68  VAL A CG1 1 ? 
ATOM   212  C CG2 . VAL A 1 33  ? -28.909 -24.202 27.802  1.000 24.201 0 68  VAL A CG2 1 ? 
ATOM   213  N N   . THR A 1 34  ? -32.234 -22.855 26.574  1.000 25.259 0 69  THR A N   1 ? 
ATOM   214  C CA  . THR A 1 34  ? -32.379 -22.414 25.191  1.000 26.331 0 69  THR A CA  1 ? 
ATOM   215  C C   . THR A 1 34  ? -31.554 -21.145 24.965  1.000 22.636 0 69  THR A C   1 ? 
ATOM   216  O O   . THR A 1 34  ? -31.374 -20.319 25.865  1.000 19.831 0 69  THR A O   1 ? 
ATOM   217  C CB  . THR A 1 34  ? -33.855 -22.203 24.783  1.000 28.632 0 69  THR A CB  1 ? 
ATOM   218  O OG1 . THR A 1 34  ? -34.328 -20.952 25.274  1.000 30.036 0 69  THR A OG1 1 ? 
ATOM   219  C CG2 . THR A 1 34  ? -34.787 -23.296 25.273  1.000 31.791 0 69  THR A CG2 1 ? 
ATOM   220  N N   . GLY A 1 35  ? -31.131 -20.961 23.714  1.000 20.374 0 70  GLY A N   1 ? 
ATOM   221  C CA  . GLY A 1 35  ? -30.454 -19.742 23.309  1.000 21.168 0 70  GLY A CA  1 ? 
ATOM   222  C C   . GLY A 1 35  ? -28.931 -19.883 23.314  1.000 19.640 0 70  GLY A C   1 ? 
ATOM   223  O O   . GLY A 1 35  ? -28.241 -19.030 22.786  1.000 19.510 0 70  GLY A O   1 ? 
ATOM   224  N N   . PHE A 1 36  ? -28.421 -20.955 23.921  1.000 19.102 0 71  PHE A N   1 ? 
ATOM   225  C CA  . PHE A 1 36  ? -26.995 -21.256 23.930  1.000 19.171 0 71  PHE A CA  1 ? 
ATOM   226  C C   . PHE A 1 36  ? -26.831 -22.757 24.200  1.000 19.957 0 71  PHE A C   1 ? 
ATOM   227  O O   . PHE A 1 36  ? -27.793 -23.428 24.583  1.000 19.360 0 71  PHE A O   1 ? 
ATOM   228  C CB  . PHE A 1 36  ? -26.276 -20.350 24.948  1.000 19.627 0 71  PHE A CB  1 ? 
ATOM   229  C CG  . PHE A 1 36  ? -26.679 -20.567 26.385  1.000 18.746 0 71  PHE A CG  1 ? 
ATOM   230  C CD1 . PHE A 1 36  ? -27.850 -20.010 26.892  1.000 19.834 0 71  PHE A CD1 1 ? 
ATOM   231  C CD2 . PHE A 1 36  ? -25.897 -21.353 27.211  1.000 18.817 0 71  PHE A CD2 1 ? 
ATOM   232  C CE1 . PHE A 1 36  ? -28.225 -20.242 28.203  1.000 18.417 0 71  PHE A CE1 1 ? 
ATOM   233  C CE2 . PHE A 1 36  ? -26.269 -21.582 28.519  1.000 18.896 0 71  PHE A CE2 1 ? 
ATOM   234  C CZ  . PHE A 1 36  ? -27.434 -21.032 29.006  1.000 18.736 0 71  PHE A CZ  1 ? 
ATOM   235  N N   . GLY A 1 37  ? -25.608 -23.287 24.004  1.000 17.655 0 72  GLY A N   1 ? 
ATOM   236  C CA  . GLY A 1 37  ? -25.390 -24.724 24.039  1.000 16.917 0 72  GLY A CA  1 ? 
ATOM   237  C C   . GLY A 1 37  ? -24.964 -25.239 25.406  1.000 18.347 0 72  GLY A C   1 ? 
ATOM   238  O O   . GLY A 1 37  ? -24.110 -26.113 25.505  1.000 19.404 0 72  GLY A O   1 ? 
ATOM   239  N N   . GLY A 1 38  ? -25.536 -24.677 26.474  1.000 18.591 0 73  GLY A N   1 ? 
ATOM   240  C CA  . GLY A 1 38  ? -25.090 -25.017 27.811  1.000 17.336 0 73  GLY A CA  1 ? 
ATOM   241  C C   . GLY A 1 38  ? -23.762 -24.322 28.110  1.000 16.848 0 73  GLY A C   1 ? 
ATOM   242  O O   . GLY A 1 38  ? -23.394 -23.351 27.443  1.000 14.160 0 73  GLY A O   1 ? 
ATOM   243  N N   . GLY A 1 39  ? -23.031 -24.838 29.100  1.000 16.645 0 74  GLY A N   1 ? 
ATOM   244  C CA  . GLY A 1 39  ? -21.744 -24.265 29.476  1.000 17.072 0 74  GLY A CA  1 ? 
ATOM   245  C C   . GLY A 1 39  ? -21.364 -24.657 30.893  1.000 17.304 0 74  GLY A C   1 ? 
ATOM   246  O O   . GLY A 1 39  ? -21.895 -25.633 31.415  1.000 19.711 0 74  GLY A O   1 ? 
ATOM   247  N N   . VAL A 1 40  ? -20.480 -23.874 31.527  1.000 17.679 0 75  VAL A N   1 ? 
ATOM   248  C CA  . VAL A 1 40  ? -19.952 -24.225 32.833  1.000 16.061 0 75  VAL A CA  1 ? 
ATOM   249  C C   . VAL A 1 40  ? -19.992 -22.990 33.726  1.000 16.165 0 75  VAL A C   1 ? 
ATOM   250  O O   . VAL A 1 40  ? -19.519 -21.927 33.320  1.000 16.457 0 75  VAL A O   1 ? 
ATOM   251  C CB  . VAL A 1 40  ? -18.516 -24.782 32.754  1.000 16.215 0 75  VAL A CB  1 ? 
ATOM   252  C CG1 . VAL A 1 40  ? -17.965 -25.105 34.145  1.000 16.355 0 75  VAL A CG1 1 ? 
ATOM   253  C CG2 . VAL A 1 40  ? -18.430 -26.007 31.855  1.000 17.466 0 75  VAL A CG2 1 ? 
ATOM   254  N N   . ILE A 1 41  ? -20.549 -23.153 34.932  1.000 14.726 0 76  ILE A N   1 ? 
ATOM   255  C CA  . ILE A 1 41  ? -20.614 -22.080 35.906  1.000 15.733 0 76  ILE A CA  1 ? 
ATOM   256  C C   . ILE A 1 41  ? -19.529 -22.337 36.937  1.000 15.646 0 76  ILE A C   1 ? 
ATOM   257  O O   . ILE A 1 41  ? -19.539 -23.396 37.562  1.000 15.370 0 76  ILE A O   1 ? 
ATOM   258  C CB  . ILE A 1 41  ? -22.003 -21.972 36.575  1.000 16.912 0 76  ILE A CB  1 ? 
ATOM   259  C CG1 . ILE A 1 41  ? -23.139 -21.965 35.552  1.000 18.225 0 76  ILE A CG1 1 ? 
ATOM   260  C CG2 . ILE A 1 41  ? -22.081 -20.763 37.495  1.000 16.989 0 76  ILE A CG2 1 ? 
ATOM   261  C CD1 . ILE A 1 41  ? -24.513 -21.912 36.178  1.000 18.339 0 76  ILE A CD1 1 ? 
ATOM   262  N N   . TYR A 1 42  ? -18.660 -21.339 37.131  1.000 14.804 0 77  TYR A N   1 ? 
ATOM   263  C CA  . TYR A 1 42  ? -17.647 -21.344 38.169  1.000 14.725 0 77  TYR A CA  1 ? 
ATOM   264  C C   . TYR A 1 42  ? -18.081 -20.397 39.279  1.000 15.275 0 77  TYR A C   1 ? 
ATOM   265  O O   . TYR A 1 42  ? -18.516 -19.292 38.992  1.000 14.449 0 77  TYR A O   1 ? 
ATOM   266  C CB  . TYR A 1 42  ? -16.297 -20.850 37.638  1.000 14.330 0 77  TYR A CB  1 ? 
ATOM   267  C CG  . TYR A 1 42  ? -15.762 -21.613 36.463  1.000 14.767 0 77  TYR A CG  1 ? 
ATOM   268  C CD1 . TYR A 1 42  ? -16.245 -21.375 35.196  1.000 14.544 0 77  TYR A CD1 1 ? 
ATOM   269  C CD2 . TYR A 1 42  ? -14.793 -22.588 36.629  1.000 15.443 0 77  TYR A CD2 1 ? 
ATOM   270  C CE1 . TYR A 1 42  ? -15.767 -22.074 34.102  1.000 16.205 0 77  TYR A CE1 1 ? 
ATOM   271  C CE2 . TYR A 1 42  ? -14.302 -23.302 35.550  1.000 16.949 0 77  TYR A CE2 1 ? 
ATOM   272  C CZ  . TYR A 1 42  ? -14.795 -23.043 34.276  1.000 16.803 0 77  TYR A CZ  1 ? 
ATOM   273  O OH  . TYR A 1 42  ? -14.337 -23.736 33.184  1.000 17.973 0 77  TYR A OH  1 ? 
ATOM   274  N N   . TYR A 1 43  ? -17.973 -20.828 40.536  1.000 15.951 0 78  TYR A N   1 ? 
ATOM   275  C CA  . TYR A 1 43  ? -18.448 -20.007 41.639  1.000 17.509 0 78  TYR A CA  1 ? 
ATOM   276  C C   . TYR A 1 43  ? -17.632 -20.296 42.889  1.000 16.608 0 78  TYR A C   1 ? 
ATOM   277  O O   . TYR A 1 43  ? -17.137 -21.411 43.100  1.000 16.096 0 78  TYR A O   1 ? 
ATOM   278  C CB  . TYR A 1 43  ? -19.949 -20.223 41.918  1.000 19.450 0 78  TYR A CB  1 ? 
ATOM   279  C CG  . TYR A 1 43  ? -20.318 -21.677 42.002  1.000 20.555 0 78  TYR A CG  1 ? 
ATOM   280  C CD1 . TYR A 1 43  ? -20.150 -22.395 43.176  1.000 22.284 0 78  TYR A CD1 1 ? 
ATOM   281  C CD2 . TYR A 1 43  ? -20.704 -22.370 40.864  1.000 21.802 0 78  TYR A CD2 1 ? 
ATOM   282  C CE1 . TYR A 1 43  ? -20.427 -23.754 43.230  1.000 22.865 0 78  TYR A CE1 1 ? 
ATOM   283  C CE2 . TYR A 1 43  ? -20.992 -23.724 40.908  1.000 21.851 0 78  TYR A CE2 1 ? 
ATOM   284  C CZ  . TYR A 1 43  ? -20.842 -24.415 42.090  1.000 22.669 0 78  TYR A CZ  1 ? 
ATOM   285  O OH  . TYR A 1 43  ? -21.097 -25.758 42.150  1.000 27.908 0 78  TYR A OH  1 ? 
ATOM   286  N N   . PRO A 1 44  ? -17.486 -19.285 43.775  1.000 16.615 0 79  PRO A N   1 ? 
ATOM   287  C CA  . PRO A 1 44  ? -16.909 -19.508 45.094  1.000 16.268 0 79  PRO A CA  1 ? 
ATOM   288  C C   . PRO A 1 44  ? -17.704 -20.534 45.902  1.000 16.137 0 79  PRO A C   1 ? 
ATOM   289  O O   . PRO A 1 44  ? -18.935 -20.535 45.878  1.000 16.303 0 79  PRO A O   1 ? 
ATOM   290  C CB  . PRO A 1 44  ? -16.963 -18.122 45.763  1.000 16.223 0 79  PRO A CB  1 ? 
ATOM   291  C CG  . PRO A 1 44  ? -17.020 -17.140 44.605  1.000 15.537 0 79  PRO A CG  1 ? 
ATOM   292  C CD  . PRO A 1 44  ? -17.791 -17.865 43.523  1.000 16.191 0 79  PRO A CD  1 ? 
ATOM   293  N N   . VAL A 1 45  ? -16.971 -21.391 46.615  1.000 16.464 0 80  VAL A N   1 ? 
ATOM   294  C CA  . VAL A 1 45  ? -17.575 -22.299 47.572  1.000 20.038 0 80  VAL A CA  1 ? 
ATOM   295  C C   . VAL A 1 45  ? -17.048 -21.988 48.973  1.000 19.779 0 80  VAL A C   1 ? 
ATOM   296  O O   . VAL A 1 45  ? -16.101 -21.213 49.138  1.000 19.089 0 80  VAL A O   1 ? 
ATOM   297  C CB  . VAL A 1 45  ? -17.336 -23.772 47.193  1.000 21.246 0 80  VAL A CB  1 ? 
ATOM   298  C CG1 . VAL A 1 45  ? -18.062 -24.144 45.917  1.000 21.927 0 80  VAL A CG1 1 ? 
ATOM   299  C CG2 . VAL A 1 45  ? -15.862 -24.092 47.078  1.000 22.452 0 80  VAL A CG2 1 ? 
ATOM   300  N N   . ASN A 1 46  ? -17.694 -22.616 49.965  1.000 21.765 0 81  ASN A N   1 ? 
ATOM   301  C CA  . ASN A 1 46  ? -17.359 -22.511 51.379  1.000 22.925 0 81  ASN A CA  1 ? 
ATOM   302  C C   . ASN A 1 46  ? -17.593 -21.070 51.838  1.000 23.408 0 81  ASN A C   1 ? 
ATOM   303  O O   . ASN A 1 46  ? -16.726 -20.494 52.485  1.000 23.767 0 81  ASN A O   1 ? 
ATOM   304  C CB  . ASN A 1 46  ? -15.942 -23.025 51.649  1.000 26.115 0 81  ASN A CB  1 ? 
ATOM   305  C CG  . ASN A 1 46  ? -15.659 -23.169 53.132  1.000 27.896 0 81  ASN A CG  1 ? 
ATOM   306  O OD1 . ASN A 1 46  ? -16.571 -23.444 53.902  1.000 30.412 0 81  ASN A OD1 1 ? 
ATOM   307  N ND2 . ASN A 1 46  ? -14.433 -22.917 53.564  1.000 29.343 0 81  ASN A ND2 1 ? 
ATOM   308  N N   . THR A 1 47  ? -18.746 -20.497 51.455  1.000 21.985 0 82  THR A N   1 ? 
ATOM   309  C CA  . THR A 1 47  ? -19.049 -19.094 51.684  1.000 22.478 0 82  THR A CA  1 ? 
ATOM   310  C C   . THR A 1 47  ? -20.550 -18.906 51.533  1.000 23.488 0 82  THR A C   1 ? 
ATOM   311  O O   . THR A 1 47  ? -21.157 -19.572 50.702  1.000 21.518 0 82  THR A O   1 ? 
ATOM   312  C CB  . THR A 1 47  ? -18.261 -18.157 50.746  1.000 22.340 0 82  THR A CB  1 ? 
ATOM   313  O OG1 . THR A 1 47  ? -18.524 -16.834 51.198  1.000 21.437 0 82  THR A OG1 1 ? 
ATOM   314  C CG2 . THR A 1 47  ? -18.625 -18.323 49.282  1.000 21.722 0 82  THR A CG2 1 ? 
ATOM   315  N N   . ASP A 1 48  ? -21.139 -17.996 52.334  1.000 24.645 0 83  ASP A N   1 ? 
ATOM   316  C CA  . ASP A 1 48  ? -22.535 -17.617 52.141  1.000 23.737 0 83  ASP A CA  1 ? 
ATOM   317  C C   . ASP A 1 48  ? -22.629 -16.241 51.488  1.000 21.637 0 83  ASP A C   1 ? 
ATOM   318  O O   . ASP A 1 48  ? -23.726 -15.718 51.341  1.000 19.280 0 83  ASP A O   1 ? 
ATOM   319  C CB  . ASP A 1 48  ? -23.338 -17.643 53.448  1.000 26.570 0 83  ASP A CB  1 ? 
ATOM   320  C CG  . ASP A 1 48  ? -23.723 -19.059 53.847  1.000 32.810 0 83  ASP A CG  1 ? 
ATOM   321  O OD1 . ASP A 1 48  ? -24.267 -19.796 52.964  1.000 34.317 0 83  ASP A OD1 1 ? 
ATOM   322  O OD2 . ASP A 1 48  ? -23.436 -19.442 55.006  1.000 36.359 0 83  ASP A OD2 1 ? 
ATOM   323  N N   . LYS A 1 49  ? -21.494 -15.678 51.058  1.000 21.153 0 84  LYS A N   1 ? 
ATOM   324  C CA  . LYS A 1 49  ? -21.495 -14.399 50.368  1.000 21.714 0 84  LYS A CA  1 ? 
ATOM   325  C C   . LYS A 1 49  ? -22.132 -14.481 48.982  1.000 20.349 0 84  LYS A C   1 ? 
ATOM   326  O O   . LYS A 1 49  ? -22.271 -15.551 48.375  1.000 18.044 0 84  LYS A O   1 ? 
ATOM   327  C CB  . LYS A 1 49  ? -20.065 -13.878 50.240  1.000 25.080 0 84  LYS A CB  1 ? 
ATOM   328  C CG  . LYS A 1 49  ? -19.455 -13.371 51.534  1.000 30.366 0 84  LYS A CG  1 ? 
ATOM   329  C CD  . LYS A 1 49  ? -18.020 -12.931 51.360  1.000 35.631 0 84  LYS A CD  1 ? 
ATOM   330  C CE  . LYS A 1 49  ? -17.520 -12.138 52.550  1.000 42.238 0 84  LYS A CE  1 ? 
ATOM   331  N NZ  . LYS A 1 49  ? -16.104 -11.747 52.374  1.000 50.081 0 84  LYS A NZ  1 ? 
ATOM   332  N N   . LYS A 1 50  ? -22.526 -13.296 48.501  1.000 19.270 0 85  LYS A N   1 ? 
ATOM   333  C CA  . LYS A 1 50  ? -22.991 -13.101 47.140  1.000 20.044 0 85  LYS A CA  1 ? 
ATOM   334  C C   . LYS A 1 50  ? -21.911 -12.344 46.373  1.000 19.867 0 85  LYS A C   1 ? 
ATOM   335  O O   . LYS A 1 50  ? -21.147 -11.613 46.992  1.000 18.873 0 85  LYS A O   1 ? 
ATOM   336  C CB  . LYS A 1 50  ? -24.303 -12.326 47.148  1.000 20.643 0 85  LYS A CB  1 ? 
ATOM   337  C CG  . LYS A 1 50  ? -25.518 -13.153 47.527  1.000 21.818 0 85  LYS A CG  1 ? 
ATOM   338  C CD  . LYS A 1 50  ? -26.820 -12.435 47.275  1.000 25.255 0 85  LYS A CD  1 ? 
ATOM   339  C CE  . LYS A 1 50  ? -28.015 -13.356 47.392  1.000 26.593 0 85  LYS A CE  1 ? 
ATOM   340  N NZ  . LYS A 1 50  ? -28.047 -14.277 46.245  1.000 28.031 0 85  LYS A NZ  1 ? 
ATOM   341  N N   . PHE A 1 51  ? -21.838 -12.598 45.052  1.000 18.306 0 86  PHE A N   1 ? 
ATOM   342  C CA  . PHE A 1 51  ? -20.793 -12.089 44.180  1.000 17.210 0 86  PHE A CA  1 ? 
ATOM   343  C C   . PHE A 1 51  ? -21.384 -11.659 42.839  1.000 16.051 0 86  PHE A C   1 ? 
ATOM   344  O O   . PHE A 1 51  ? -22.370 -12.220 42.375  1.000 14.431 0 86  PHE A O   1 ? 
ATOM   345  C CB  . PHE A 1 51  ? -19.720 -13.147 43.927  1.000 17.340 0 86  PHE A CB  1 ? 
ATOM   346  C CG  . PHE A 1 51  ? -19.097 -13.700 45.186  1.000 17.328 0 86  PHE A CG  1 ? 
ATOM   347  C CD1 . PHE A 1 51  ? -19.680 -14.786 45.827  1.000 17.202 0 86  PHE A CD1 1 ? 
ATOM   348  C CD2 . PHE A 1 51  ? -17.968 -13.113 45.751  1.000 17.749 0 86  PHE A CD2 1 ? 
ATOM   349  C CE1 . PHE A 1 51  ? -19.126 -15.310 46.990  1.000 18.602 0 86  PHE A CE1 1 ? 
ATOM   350  C CE2 . PHE A 1 51  ? -17.423 -13.619 46.926  1.000 18.735 0 86  PHE A CE2 1 ? 
ATOM   351  C CZ  . PHE A 1 51  ? -17.998 -14.737 47.535  1.000 18.032 0 86  PHE A CZ  1 ? 
ATOM   352  N N   . PRO A 1 52  ? -20.829 -10.628 42.172  1.000 15.927 0 87  PRO A N   1 ? 
ATOM   353  C CA  . PRO A 1 52  ? -21.295 -10.269 40.828  1.000 15.879 0 87  PRO A CA  1 ? 
ATOM   354  C C   . PRO A 1 52  ? -21.105 -11.426 39.849  1.000 16.029 0 87  PRO A C   1 ? 
ATOM   355  O O   . PRO A 1 52  ? -20.278 -12.327 40.082  1.000 16.341 0 87  PRO A O   1 ? 
ATOM   356  C CB  . PRO A 1 52  ? -20.427 -9.065  40.435  1.000 16.930 0 87  PRO A CB  1 ? 
ATOM   357  C CG  . PRO A 1 52  ? -19.932 -8.517  41.762  1.000 16.087 0 87  PRO A CG  1 ? 
ATOM   358  C CD  . PRO A 1 52  ? -19.746 -9.736  42.646  1.000 16.255 0 87  PRO A CD  1 ? 
ATOM   359  N N   . GLY A 1 53  ? -21.928 -11.412 38.798  1.000 15.345 0 88  GLY A N   1 ? 
ATOM   360  C CA  . GLY A 1 53  ? -21.895 -12.439 37.777  1.000 16.038 0 88  GLY A CA  1 ? 
ATOM   361  C C   . GLY A 1 53  ? -21.238 -11.946 36.501  1.000 15.019 0 88  GLY A C   1 ? 
ATOM   362  O O   . GLY A 1 53  ? -21.322 -10.772 36.181  1.000 14.783 0 88  GLY A O   1 ? 
ATOM   363  N N   . ILE A 1 54  ? -20.597 -12.874 35.789  1.000 15.429 0 89  ILE A N   1 ? 
ATOM   364  C CA  . ILE A 1 54  ? -19.926 -12.601 34.529  1.000 14.760 0 89  ILE A CA  1 ? 
ATOM   365  C C   . ILE A 1 54  ? -20.250 -13.736 33.576  1.000 15.416 0 89  ILE A C   1 ? 
ATOM   366  O O   . ILE A 1 54  ? -20.072 -14.893 33.932  1.000 15.809 0 89  ILE A O   1 ? 
ATOM   367  C CB  . ILE A 1 54  ? -18.395 -12.469 34.680  1.000 14.762 0 89  ILE A CB  1 ? 
ATOM   368  C CG1 . ILE A 1 54  ? -18.005 -11.387 35.693  1.000 15.541 0 89  ILE A CG1 1 ? 
ATOM   369  C CG2 . ILE A 1 54  ? -17.770 -12.235 33.312  1.000 14.168 0 89  ILE A CG2 1 ? 
ATOM   370  C CD1 . ILE A 1 54  ? -16.572 -11.489 36.198  1.000 16.589 0 89  ILE A CD1 1 ? 
ATOM   371  N N   . VAL A 1 55  ? -20.717 -13.391 32.374  1.000 15.061 0 90  VAL A N   1 ? 
ATOM   372  C CA  . VAL A 1 55  ? -21.002 -14.368 31.342  1.000 15.604 0 90  VAL A CA  1 ? 
ATOM   373  C C   . VAL A 1 55  ? -19.997 -14.177 30.220  1.000 15.159 0 90  VAL A C   1 ? 
ATOM   374  O O   . VAL A 1 55  ? -19.798 -13.047 29.760  1.000 15.357 0 90  VAL A O   1 ? 
ATOM   375  C CB  . VAL A 1 55  ? -22.445 -14.242 30.828  1.000 16.500 0 90  VAL A CB  1 ? 
ATOM   376  C CG1 . VAL A 1 55  ? -22.748 -15.263 29.732  1.000 16.859 0 90  VAL A CG1 1 ? 
ATOM   377  C CG2 . VAL A 1 55  ? -23.429 -14.386 31.974  1.000 16.919 0 90  VAL A CG2 1 ? 
ATOM   378  N N   . MET A 1 56  ? -19.395 -15.282 29.784  1.000 15.254 0 91  MET A N   1 ? 
ATOM   379  C CA  . MET A 1 56  ? -18.295 -15.250 28.836  1.000 16.784 0 91  MET A CA  1 ? 
ATOM   380  C C   . MET A 1 56  ? -18.586 -16.167 27.665  1.000 15.408 0 91  MET A C   1 ? 
ATOM   381  O O   . MET A 1 56  ? -19.035 -17.296 27.867  1.000 15.902 0 91  MET A O   1 ? 
ATOM   382  C CB  . MET A 1 56  ? -16.990 -15.720 29.494  1.000 18.992 0 91  MET A CB  1 ? 
ATOM   383  C CG  . MET A 1 56  ? -16.592 -14.874 30.699  1.000 22.510 0 91  MET A CG  1 ? 
ATOM   384  S SD  . MET A 1 56  ? -14.783 -14.818 30.943  1.000 25.077 0 91  MET A SD  1 ? 
ATOM   385  C CE  . MET A 1 56  ? -14.408 -16.562 31.069  1.000 23.290 0 91  MET A CE  1 ? 
ATOM   386  N N   . ALA A 1 57  ? -18.271 -15.689 26.459  1.000 14.843 0 92  ALA A N   1 ? 
ATOM   387  C CA  . ALA A 1 57  ? -18.368 -16.493 25.250  1.000 15.973 0 92  ALA A CA  1 ? 
ATOM   388  C C   . ALA A 1 57  ? -16.967 -16.784 24.720  1.000 15.610 0 92  ALA A C   1 ? 
ATOM   389  O O   . ALA A 1 57  ? -16.162 -15.874 24.522  1.000 15.766 0 92  ALA A O   1 ? 
ATOM   390  C CB  . ALA A 1 57  ? -19.187 -15.772 24.202  1.000 15.785 0 92  ALA A CB  1 ? 
ATOM   391  N N   . PRO A 1 58  ? -16.651 -18.049 24.394  1.000 15.505 0 93  PRO A N   1 ? 
ATOM   392  C CA  . PRO A 1 58  ? -15.401 -18.365 23.699  1.000 16.464 0 93  PRO A CA  1 ? 
ATOM   393  C C   . PRO A 1 58  ? -15.507 -18.085 22.198  1.000 15.929 0 93  PRO A C   1 ? 
ATOM   394  O O   . PRO A 1 58  ? -16.552 -17.670 21.701  1.000 15.943 0 93  PRO A O   1 ? 
ATOM   395  C CB  . PRO A 1 58  ? -15.250 -19.867 23.992  1.000 16.012 0 93  PRO A CB  1 ? 
ATOM   396  C CG  . PRO A 1 58  ? -16.699 -20.365 23.979  1.000 16.502 0 93  PRO A CG  1 ? 
ATOM   397  C CD  . PRO A 1 58  ? -17.513 -19.227 24.572  1.000 16.087 0 93  PRO A CD  1 ? 
ATOM   398  N N   . GLY A 1 59  ? -14.392 -18.267 21.485  1.000 15.213 0 94  GLY A N   1 ? 
ATOM   399  C CA  . GLY A 1 59  ? -14.376 -18.057 20.043  1.000 15.303 0 94  GLY A CA  1 ? 
ATOM   400  C C   . GLY A 1 59  ? -15.365 -18.993 19.348  1.000 15.805 0 94  GLY A C   1 ? 
ATOM   401  O O   . GLY A 1 59  ? -15.873 -19.959 19.930  1.000 16.440 0 94  GLY A O   1 ? 
ATOM   402  N N   . TYR A 1 60  ? -15.567 -18.709 18.069  1.000 15.816 0 95  TYR A N   1 ? 
ATOM   403  C CA  . TYR A 1 60  ? -16.582 -19.337 17.256  1.000 16.271 0 95  TYR A CA  1 ? 
ATOM   404  C C   . TYR A 1 60  ? -16.388 -20.846 17.189  1.000 16.405 0 95  TYR A C   1 ? 
ATOM   405  O O   . TYR A 1 60  ? -17.359 -21.571 17.434  1.000 16.665 0 95  TYR A O   1 ? 
ATOM   406  C CB  . TYR A 1 60  ? -16.614 -18.676 15.873  1.000 16.414 0 95  TYR A CB  1 ? 
ATOM   407  C CG  . TYR A 1 60  ? -17.685 -19.170 14.937  1.000 15.197 0 95  TYR A CG  1 ? 
ATOM   408  C CD1 . TYR A 1 60  ? -18.965 -19.431 15.382  1.000 15.945 0 95  TYR A CD1 1 ? 
ATOM   409  C CD2 . TYR A 1 60  ? -17.418 -19.354 13.595  1.000 15.965 0 95  TYR A CD2 1 ? 
ATOM   410  C CE1 . TYR A 1 60  ? -19.937 -19.928 14.533  1.000 15.919 0 95  TYR A CE1 1 ? 
ATOM   411  C CE2 . TYR A 1 60  ? -18.402 -19.761 12.713  1.000 16.379 0 95  TYR A CE2 1 ? 
ATOM   412  C CZ  . TYR A 1 60  ? -19.662 -20.082 13.186  1.000 16.607 0 95  TYR A CZ  1 ? 
ATOM   413  O OH  . TYR A 1 60  ? -20.628 -20.530 12.304  1.000 17.390 0 95  TYR A OH  1 ? 
ATOM   414  N N   . THR A 1 61  ? -15.162 -21.323 16.879  1.000 16.065 0 96  THR A N   1 ? 
ATOM   415  C CA  . THR A 1 61  ? -14.950 -22.761 16.745  1.000 15.101 0 96  THR A CA  1 ? 
ATOM   416  C C   . THR A 1 61  ? -14.706 -23.449 18.094  1.000 14.826 0 96  THR A C   1 ? 
ATOM   417  O O   . THR A 1 61  ? -14.490 -24.652 18.133  1.000 14.476 0 96  THR A O   1 ? 
ATOM   418  C CB  . THR A 1 61  ? -13.838 -23.096 15.750  1.000 14.780 0 96  THR A CB  1 ? 
ATOM   419  O OG1 . THR A 1 61  ? -12.612 -22.652 16.320  1.000 15.822 0 96  THR A OG1 1 ? 
ATOM   420  C CG2 . THR A 1 61  ? -14.093 -22.485 14.383  1.000 15.869 0 96  THR A CG2 1 ? 
ATOM   421  N N   . ALA A 1 62  ? -14.792 -22.698 19.197  1.000 14.971 0 97  ALA A N   1 ? 
ATOM   422  C CA  . ALA A 1 62  ? -14.421 -23.182 20.510  1.000 15.195 0 97  ALA A CA  1 ? 
ATOM   423  C C   . ALA A 1 62  ? -15.639 -23.539 21.358  1.000 15.925 0 97  ALA A C   1 ? 
ATOM   424  O O   . ALA A 1 62  ? -16.772 -23.158 21.052  1.000 16.741 0 97  ALA A O   1 ? 
ATOM   425  C CB  . ALA A 1 62  ? -13.607 -22.109 21.173  1.000 15.292 0 97  ALA A CB  1 ? 
ATOM   426  N N   . ASP A 1 63  ? -15.374 -24.251 22.456  1.000 16.220 0 98  ASP A N   1 ? 
ATOM   427  C CA  . ASP A 1 63  ? -16.362 -24.427 23.502  1.000 17.657 0 98  ASP A CA  1 ? 
ATOM   428  C C   . ASP A 1 63  ? -15.826 -23.812 24.792  1.000 17.743 0 98  ASP A C   1 ? 
ATOM   429  O O   . ASP A 1 63  ? -14.721 -23.250 24.810  1.000 16.980 0 98  ASP A O   1 ? 
ATOM   430  C CB  . ASP A 1 63  ? -16.766 -25.902 23.631  1.000 19.739 0 98  ASP A CB  1 ? 
ATOM   431  C CG  . ASP A 1 63  ? -15.700 -26.836 24.190  1.000 21.940 0 98  ASP A CG  1 ? 
ATOM   432  O OD1 . ASP A 1 63  ? -14.659 -26.332 24.658  1.000 22.613 0 98  ASP A OD1 1 ? 
ATOM   433  O OD2 . ASP A 1 63  ? -15.932 -28.069 24.181  1.000 21.722 0 98  ASP A OD2 1 ? 
ATOM   434  N N   . ALA A 1 64  ? -16.596 -23.978 25.872  1.000 17.158 0 99  ALA A N   1 ? 
ATOM   435  C CA  . ALA A 1 64  ? -16.329 -23.294 27.129  1.000 18.023 0 99  ALA A CA  1 ? 
ATOM   436  C C   . ALA A 1 64  ? -14.946 -23.641 27.687  1.000 17.588 0 99  ALA A C   1 ? 
ATOM   437  O O   . ALA A 1 64  ? -14.364 -22.836 28.417  1.000 16.507 0 99  ALA A O   1 ? 
ATOM   438  C CB  . ALA A 1 64  ? -17.408 -23.645 28.124  1.000 20.003 0 99  ALA A CB  1 ? 
ATOM   439  N N   . SER A 1 65  ? -14.467 -24.859 27.394  1.000 16.404 0 100 SER A N   1 ? 
ATOM   440  C CA  . SER A 1 65  ? -13.145 -25.335 27.770  1.000 17.754 0 100 SER A CA  1 ? 
ATOM   441  C C   . SER A 1 65  ? -12.043 -24.343 27.392  1.000 17.378 0 100 SER A C   1 ? 
ATOM   442  O O   . SER A 1 65  ? -11.043 -24.258 28.098  1.000 17.424 0 100 SER A O   1 ? 
ATOM   443  C CB  . SER A 1 65  ? -12.885 -26.709 27.139  1.000 19.167 0 100 SER A CB  1 ? 
ATOM   444  O OG  . SER A 1 65  ? -11.553 -27.138 27.334  1.000 21.322 0 100 SER A OG  1 ? 
ATOM   445  N N   . SER A 1 66  ? -12.213 -23.577 26.295  1.000 16.974 0 101 SER A N   1 ? 
ATOM   446  C CA  A SER A 1 66  ? -11.148 -22.717 25.806  0.500 17.437 0 101 SER A CA  1 ? 
ATOM   447  C CA  B SER A 1 66  ? -11.154 -22.712 25.801  0.500 16.447 0 101 SER A CA  1 ? 
ATOM   448  C C   . SER A 1 66  ? -10.941 -21.515 26.726  1.000 17.300 0 101 SER A C   1 ? 
ATOM   449  O O   . SER A 1 66  ? -9.895  -20.871 26.653  1.000 18.130 0 101 SER A O   1 ? 
ATOM   450  C CB  A SER A 1 66  ? -11.397 -22.284 24.387  0.500 18.149 0 101 SER A CB  1 ? 
ATOM   451  C CB  B SER A 1 66  ? -11.413 -22.283 24.375  0.500 16.029 0 101 SER A CB  1 ? 
ATOM   452  O OG  A SER A 1 66  ? -12.351 -21.247 24.340  0.500 19.040 0 101 SER A OG  1 ? 
ATOM   453  O OG  B SER A 1 66  ? -11.127 -23.344 23.462  0.500 14.268 0 101 SER A OG  1 ? 
ATOM   454  N N   . LEU A 1 67  ? -11.922 -21.211 27.609  1.000 17.568 0 102 LEU A N   1 ? 
ATOM   455  C CA  . LEU A 1 67  ? -11.752 -20.144 28.589  1.000 17.060 0 102 LEU A CA  1 ? 
ATOM   456  C C   . LEU A 1 67  ? -11.815 -20.682 30.019  1.000 17.423 0 102 LEU A C   1 ? 
ATOM   457  O O   . LEU A 1 67  ? -12.057 -19.923 30.971  1.000 17.621 0 102 LEU A O   1 ? 
ATOM   458  C CB  . LEU A 1 67  ? -12.814 -19.068 28.326  1.000 16.962 0 102 LEU A CB  1 ? 
ATOM   459  C CG  . LEU A 1 67  ? -12.624 -18.249 27.046  1.000 17.969 0 102 LEU A CG  1 ? 
ATOM   460  C CD1 . LEU A 1 67  ? -13.701 -17.185 26.919  1.000 18.073 0 102 LEU A CD1 1 ? 
ATOM   461  C CD2 . LEU A 1 67  ? -11.248 -17.583 27.010  1.000 18.583 0 102 LEU A CD2 1 ? 
ATOM   462  N N   . ASP A 1 68  ? -11.543 -21.978 30.193  1.000 17.638 0 103 ASP A N   1 ? 
ATOM   463  C CA  . ASP A 1 68  ? -11.645 -22.596 31.511  1.000 17.719 0 103 ASP A CA  1 ? 
ATOM   464  C C   . ASP A 1 68  ? -10.709 -21.902 32.506  1.000 16.173 0 103 ASP A C   1 ? 
ATOM   465  O O   . ASP A 1 68  ? -11.114 -21.615 33.620  1.000 17.224 0 103 ASP A O   1 ? 
ATOM   466  C CB  . ASP A 1 68  ? -11.393 -24.099 31.453  1.000 18.576 0 103 ASP A CB  1 ? 
ATOM   467  C CG  . ASP A 1 68  ? -11.245 -24.717 32.835  1.000 20.949 0 103 ASP A CG  1 ? 
ATOM   468  O OD1 . ASP A 1 68  ? -12.262 -24.931 33.528  1.000 20.723 0 103 ASP A OD1 1 ? 
ATOM   469  O OD2 . ASP A 1 68  ? -10.107 -24.914 33.231  1.000 23.710 0 103 ASP A OD2 1 ? 
ATOM   470  N N   . TRP A 1 69  ? -9.467  -21.609 32.105  1.000 15.501 0 104 TRP A N   1 ? 
ATOM   471  C CA  . TRP A 1 69  ? -8.476  -21.046 33.016  1.000 15.489 0 104 TRP A CA  1 ? 
ATOM   472  C C   . TRP A 1 69  ? -8.953  -19.692 33.564  1.000 15.448 0 104 TRP A C   1 ? 
ATOM   473  O O   . TRP A 1 69  ? -8.728  -19.373 34.733  1.000 14.138 0 104 TRP A O   1 ? 
ATOM   474  C CB  . TRP A 1 69  ? -7.104  -20.930 32.323  1.000 15.018 0 104 TRP A CB  1 ? 
ATOM   475  C CG  . TRP A 1 69  ? -7.023  -19.785 31.344  1.000 14.536 0 104 TRP A CG  1 ? 
ATOM   476  C CD1 . TRP A 1 69  ? -7.288  -19.817 30.003  1.000 14.159 0 104 TRP A CD1 1 ? 
ATOM   477  C CD2 . TRP A 1 69  ? -6.656  -18.425 31.642  1.000 13.173 0 104 TRP A CD2 1 ? 
ATOM   478  N NE1 . TRP A 1 69  ? -7.115  -18.572 29.447  1.000 13.101 0 104 TRP A NE1 1 ? 
ATOM   479  C CE2 . TRP A 1 69  ? -6.738  -17.692 30.431  1.000 13.198 0 104 TRP A CE2 1 ? 
ATOM   480  C CE3 . TRP A 1 69  ? -6.280  -17.744 32.812  1.000 13.239 0 104 TRP A CE3 1 ? 
ATOM   481  C CZ2 . TRP A 1 69  ? -6.453  -16.322 30.369  1.000 12.128 0 104 TRP A CZ2 1 ? 
ATOM   482  C CZ3 . TRP A 1 69  ? -5.987  -16.387 32.748  1.000 12.988 0 104 TRP A CZ3 1 ? 
ATOM   483  C CH2 . TRP A 1 69  ? -6.081  -15.687 31.541  1.000 12.244 0 104 TRP A CH2 1 ? 
ATOM   484  N N   . LEU A 1 70  ? -9.598  -18.886 32.708  1.000 15.555 0 105 LEU A N   1 ? 
ATOM   485  C CA  . LEU A 1 70  ? -10.032 -17.544 33.084  1.000 16.822 0 105 LEU A CA  1 ? 
ATOM   486  C C   . LEU A 1 70  ? -11.303 -17.577 33.927  1.000 17.412 0 105 LEU A C   1 ? 
ATOM   487  O O   . LEU A 1 70  ? -11.482 -16.748 34.832  1.000 18.257 0 105 LEU A O   1 ? 
ATOM   488  C CB  . LEU A 1 70  ? -10.224 -16.726 31.796  1.000 16.227 0 105 LEU A CB  1 ? 
ATOM   489  C CG  . LEU A 1 70  ? -10.553 -15.242 31.965  1.000 16.464 0 105 LEU A CG  1 ? 
ATOM   490  C CD1 . LEU A 1 70  ? -9.538  -14.510 32.817  1.000 16.995 0 105 LEU A CD1 1 ? 
ATOM   491  C CD2 . LEU A 1 70  ? -10.621 -14.576 30.610  1.000 16.716 0 105 LEU A CD2 1 ? 
ATOM   492  N N   . GLY A 1 71  ? -12.214 -18.512 33.612  1.000 17.619 0 106 GLY A N   1 ? 
ATOM   493  C CA  . GLY A 1 71  ? -13.383 -18.732 34.444  1.000 17.421 0 106 GLY A CA  1 ? 
ATOM   494  C C   . GLY A 1 71  ? -12.980 -19.058 35.882  1.000 17.349 0 106 GLY A C   1 ? 
ATOM   495  O O   . GLY A 1 71  ? -13.527 -18.483 36.815  1.000 18.120 0 106 GLY A O   1 ? 
ATOM   496  N N   . LYS A 1 72  ? -12.000 -19.955 36.047  1.000 18.507 0 107 LYS A N   1 ? 
ATOM   497  C CA  . LYS A 1 72  ? -11.558 -20.359 37.372  1.000 20.394 0 107 LYS A CA  1 ? 
ATOM   498  C C   . LYS A 1 72  ? -10.860 -19.183 38.031  1.000 19.025 0 107 LYS A C   1 ? 
ATOM   499  O O   . LYS A 1 72  ? -11.019 -18.964 39.219  1.000 17.047 0 107 LYS A O   1 ? 
ATOM   500  C CB  . LYS A 1 72  ? -10.473 -21.433 37.465  1.000 25.117 0 107 LYS A CB  1 ? 
ATOM   501  C CG  . LYS A 1 72  ? -10.713 -22.784 36.831  1.000 35.820 0 107 LYS A CG  1 ? 
ATOM   502  C CD  . LYS A 1 72  ? -9.592  -23.758 37.208  1.000 39.777 0 107 LYS A CD  1 ? 
ATOM   503  C CE  . LYS A 1 72  ? -9.312  -24.852 36.199  1.000 43.330 0 107 LYS A CE  1 ? 
ATOM   504  N NZ  . LYS A 1 72  ? -10.433 -25.816 36.112  1.000 46.391 0 107 LYS A NZ  1 ? 
ATOM   505  N N   . HIS A 1 73  ? -10.027 -18.463 37.267  1.000 19.142 0 108 HIS A N   1 ? 
ATOM   506  C CA  . HIS A 1 73  ? -9.246  -17.386 37.837  1.000 17.332 0 108 HIS A CA  1 ? 
ATOM   507  C C   . HIS A 1 73  ? -10.169 -16.301 38.388  1.000 17.151 0 108 HIS A C   1 ? 
ATOM   508  O O   . HIS A 1 73  ? -10.042 -15.885 39.545  1.000 17.063 0 108 HIS A O   1 ? 
ATOM   509  C CB  . HIS A 1 73  ? -8.258  -16.826 36.812  1.000 17.434 0 108 HIS A CB  1 ? 
ATOM   510  C CG  . HIS A 1 73  ? -7.394  -15.800 37.449  1.000 18.389 0 108 HIS A CG  1 ? 
ATOM   511  N ND1 . HIS A 1 73  ? -7.627  -14.447 37.317  1.000 19.815 0 108 HIS A ND1 1 ? 
ATOM   512  C CD2 . HIS A 1 73  ? -6.330  -15.924 38.249  1.000 17.445 0 108 HIS A CD2 1 ? 
ATOM   513  C CE1 . HIS A 1 73  ? -6.700  -13.789 38.010  1.000 18.371 0 108 HIS A CE1 1 ? 
ATOM   514  N NE2 . HIS A 1 73  ? -5.913  -14.667 38.581  1.000 18.781 0 108 HIS A NE2 1 ? 
ATOM   515  N N   . LEU A 1 74  ? -11.114 -15.858 37.560  1.000 16.081 0 109 LEU A N   1 ? 
ATOM   516  C CA  . LEU A 1 74  ? -12.025 -14.801 37.962  1.000 16.343 0 109 LEU A CA  1 ? 
ATOM   517  C C   . LEU A 1 74  ? -12.862 -15.257 39.157  1.000 17.671 0 109 LEU A C   1 ? 
ATOM   518  O O   . LEU A 1 74  ? -13.028 -14.498 40.111  1.000 18.831 0 109 LEU A O   1 ? 
ATOM   519  C CB  . LEU A 1 74  ? -12.900 -14.381 36.773  1.000 16.587 0 109 LEU A CB  1 ? 
ATOM   520  C CG  . LEU A 1 74  ? -12.193 -13.572 35.679  1.000 17.428 0 109 LEU A CG  1 ? 
ATOM   521  C CD1 . LEU A 1 74  ? -13.053 -13.437 34.438  1.000 17.330 0 109 LEU A CD1 1 ? 
ATOM   522  C CD2 . LEU A 1 74  ? -11.764 -12.189 36.171  1.000 18.418 0 109 LEU A CD2 1 ? 
ATOM   523  N N   . ALA A 1 75  ? -13.395 -16.481 39.110  1.000 17.031 0 110 ALA A N   1 ? 
ATOM   524  C CA  . ALA A 1 75  ? -14.246 -16.958 40.190  1.000 17.458 0 110 ALA A CA  1 ? 
ATOM   525  C C   . ALA A 1 75  ? -13.491 -16.952 41.516  1.000 16.860 0 110 ALA A C   1 ? 
ATOM   526  O O   . ALA A 1 75  ? -14.072 -16.619 42.544  1.000 15.938 0 110 ALA A O   1 ? 
ATOM   527  C CB  . ALA A 1 75  ? -14.794 -18.343 39.905  1.000 17.497 0 110 ALA A CB  1 ? 
ATOM   528  N N   . SER A 1 76  ? -12.211 -17.341 41.488  1.000 16.086 0 111 SER A N   1 ? 
ATOM   529  C CA  . SER A 1 76  ? -11.378 -17.403 42.684  1.000 17.055 0 111 SER A CA  1 ? 
ATOM   530  C C   . SER A 1 76  ? -11.214 -16.038 43.357  1.000 16.494 0 111 SER A C   1 ? 
ATOM   531  O O   . SER A 1 76  ? -10.948 -15.977 44.559  1.000 15.640 0 111 SER A O   1 ? 
ATOM   532  C CB  . SER A 1 76  ? -10.022 -18.052 42.387  1.000 16.390 0 111 SER A CB  1 ? 
ATOM   533  O OG  . SER A 1 76  ? -9.176  -17.180 41.681  1.000 15.034 0 111 SER A OG  1 ? 
ATOM   534  N N   . HIS A 1 77  ? -11.386 -14.956 42.582  1.000 16.223 0 112 HIS A N   1 ? 
ATOM   535  C CA  . HIS A 1 77  ? -11.303 -13.596 43.087  1.000 17.855 0 112 HIS A CA  1 ? 
ATOM   536  C C   . HIS A 1 77  ? -12.670 -13.050 43.513  1.000 17.935 0 112 HIS A C   1 ? 
ATOM   537  O O   . HIS A 1 77  ? -12.744 -11.891 43.875  1.000 19.252 0 112 HIS A O   1 ? 
ATOM   538  C CB  . HIS A 1 77  ? -10.650 -12.675 42.046  1.000 18.042 0 112 HIS A CB  1 ? 
ATOM   539  C CG  . HIS A 1 77  ? -9.175  -12.841 42.020  1.000 19.045 0 112 HIS A CG  1 ? 
ATOM   540  N ND1 . HIS A 1 77  ? -8.353  -12.076 42.824  1.000 17.569 0 112 HIS A ND1 1 ? 
ATOM   541  C CD2 . HIS A 1 77  ? -8.370  -13.704 41.359  1.000 18.781 0 112 HIS A CD2 1 ? 
ATOM   542  C CE1 . HIS A 1 77  ? -7.099  -12.457 42.645  1.000 18.211 0 112 HIS A CE1 1 ? 
ATOM   543  N NE2 . HIS A 1 77  ? -7.073  -13.442 41.749  1.000 18.470 0 112 HIS A NE2 1 ? 
ATOM   544  N N   . GLY A 1 78  ? -13.731 -13.874 43.495  1.000 15.914 0 113 GLY A N   1 ? 
ATOM   545  C CA  . GLY A 1 78  ? -15.025 -13.493 44.047  1.000 15.520 0 113 GLY A CA  1 ? 
ATOM   546  C C   . GLY A 1 78  ? -16.029 -13.084 42.966  1.000 15.582 0 113 GLY A C   1 ? 
ATOM   547  O O   . GLY A 1 78  ? -16.581 -11.980 43.000  1.000 14.390 0 113 GLY A O   1 ? 
ATOM   548  N N   . PHE A 1 79  ? -16.238 -13.992 41.997  1.000 15.459 0 114 PHE A N   1 ? 
ATOM   549  C CA  . PHE A 1 79  ? -17.240 -13.832 40.953  1.000 15.594 0 114 PHE A CA  1 ? 
ATOM   550  C C   . PHE A 1 79  ? -17.883 -15.186 40.633  1.000 16.325 0 114 PHE A C   1 ? 
ATOM   551  O O   . PHE A 1 79  ? -17.251 -16.243 40.780  1.000 15.937 0 114 PHE A O   1 ? 
ATOM   552  C CB  . PHE A 1 79  ? -16.629 -13.267 39.666  1.000 15.435 0 114 PHE A CB  1 ? 
ATOM   553  C CG  . PHE A 1 79  ? -16.069 -11.891 39.825  1.000 15.221 0 114 PHE A CG  1 ? 
ATOM   554  C CD1 . PHE A 1 79  ? -16.908 -10.787 39.856  1.000 16.129 0 114 PHE A CD1 1 ? 
ATOM   555  C CD2 . PHE A 1 79  ? -14.716 -11.701 40.028  1.000 15.388 0 114 PHE A CD2 1 ? 
ATOM   556  C CE1 . PHE A 1 79  ? -16.389 -9.510  40.031  1.000 15.824 0 114 PHE A CE1 1 ? 
ATOM   557  C CE2 . PHE A 1 79  ? -14.192 -10.426 40.171  1.000 15.604 0 114 PHE A CE2 1 ? 
ATOM   558  C CZ  . PHE A 1 79  ? -15.022 -9.332  40.176  1.000 15.967 0 114 PHE A CZ  1 ? 
ATOM   559  N N   . VAL A 1 80  ? -19.165 -15.118 40.236  1.000 15.389 0 115 VAL A N   1 ? 
ATOM   560  C CA  . VAL A 1 80  ? -19.856 -16.220 39.581  1.000 16.249 0 115 VAL A CA  1 ? 
ATOM   561  C C   . VAL A 1 80  ? -19.681 -16.062 38.068  1.000 16.398 0 115 VAL A C   1 ? 
ATOM   562  O O   . VAL A 1 80  ? -20.114 -15.066 37.483  1.000 16.223 0 115 VAL A O   1 ? 
ATOM   563  C CB  . VAL A 1 80  ? -21.348 -16.262 39.970  1.000 15.674 0 115 VAL A CB  1 ? 
ATOM   564  C CG1 . VAL A 1 80  ? -22.087 -17.416 39.300  1.000 15.089 0 115 VAL A CG1 1 ? 
ATOM   565  C CG2 . VAL A 1 80  ? -21.519 -16.316 41.470  1.000 15.888 0 115 VAL A CG2 1 ? 
ATOM   566  N N   . VAL A 1 81  ? -19.033 -17.045 37.440  1.000 15.206 0 116 VAL A N   1 ? 
ATOM   567  C CA  . VAL A 1 81  ? -18.619 -16.876 36.055  1.000 16.636 0 116 VAL A CA  1 ? 
ATOM   568  C C   . VAL A 1 81  ? -19.228 -18.011 35.253  1.000 16.233 0 116 VAL A C   1 ? 
ATOM   569  O O   . VAL A 1 81  ? -19.060 -19.173 35.614  1.000 15.796 0 116 VAL A O   1 ? 
ATOM   570  C CB  . VAL A 1 81  ? -17.081 -16.818 35.890  1.000 16.073 0 116 VAL A CB  1 ? 
ATOM   571  C CG1 . VAL A 1 81  ? -16.668 -16.476 34.465  1.000 16.424 0 116 VAL A CG1 1 ? 
ATOM   572  C CG2 . VAL A 1 81  ? -16.457 -15.816 36.851  1.000 16.560 0 116 VAL A CG2 1 ? 
ATOM   573  N N   . PHE A 1 82  ? -19.905 -17.643 34.161  1.000 14.980 0 117 PHE A N   1 ? 
ATOM   574  C CA  . PHE A 1 82  ? -20.637 -18.586 33.345  1.000 15.976 0 117 PHE A CA  1 ? 
ATOM   575  C C   . PHE A 1 82  ? -20.058 -18.572 31.942  1.000 15.118 0 117 PHE A C   1 ? 
ATOM   576  O O   . PHE A 1 82  ? -20.184 -17.568 31.256  1.000 14.477 0 117 PHE A O   1 ? 
ATOM   577  C CB  . PHE A 1 82  ? -22.123 -18.235 33.330  1.000 16.503 0 117 PHE A CB  1 ? 
ATOM   578  C CG  . PHE A 1 82  ? -23.026 -19.233 32.654  1.000 17.375 0 117 PHE A CG  1 ? 
ATOM   579  C CD1 . PHE A 1 82  ? -22.630 -20.554 32.454  1.000 18.948 0 117 PHE A CD1 1 ? 
ATOM   580  C CD2 . PHE A 1 82  ? -24.291 -18.844 32.224  1.000 19.687 0 117 PHE A CD2 1 ? 
ATOM   581  C CE1 . PHE A 1 82  ? -23.465 -21.471 31.841  1.000 19.645 0 117 PHE A CE1 1 ? 
ATOM   582  C CE2 . PHE A 1 82  ? -25.132 -19.765 31.611  1.000 19.941 0 117 PHE A CE2 1 ? 
ATOM   583  C CZ  . PHE A 1 82  ? -24.723 -21.072 31.431  1.000 20.687 0 117 PHE A CZ  1 ? 
ATOM   584  N N   . VAL A 1 83  ? -19.399 -19.673 31.556  1.000 14.955 0 118 VAL A N   1 ? 
ATOM   585  C CA  . VAL A 1 83  ? -18.770 -19.773 30.248  1.000 15.789 0 118 VAL A CA  1 ? 
ATOM   586  C C   . VAL A 1 83  ? -19.669 -20.638 29.372  1.000 16.267 0 118 VAL A C   1 ? 
ATOM   587  O O   . VAL A 1 83  ? -19.976 -21.776 29.726  1.000 14.918 0 118 VAL A O   1 ? 
ATOM   588  C CB  . VAL A 1 83  ? -17.332 -20.325 30.314  1.000 15.868 0 118 VAL A CB  1 ? 
ATOM   589  C CG1 . VAL A 1 83  ? -16.639 -20.245 28.958  1.000 16.589 0 118 VAL A CG1 1 ? 
ATOM   590  C CG2 . VAL A 1 83  ? -16.503 -19.617 31.356  1.000 16.535 0 118 VAL A CG2 1 ? 
ATOM   591  N N   . LEU A 1 84  ? -20.053 -20.080 28.221  1.000 17.114 0 119 LEU A N   1 ? 
ATOM   592  C CA  . LEU A 1 84  ? -21.069 -20.678 27.360  1.000 17.912 0 119 LEU A CA  1 ? 
ATOM   593  C C   . LEU A 1 84  ? -20.425 -21.525 26.263  1.000 16.727 0 119 LEU A C   1 ? 
ATOM   594  O O   . LEU A 1 84  ? -19.282 -21.290 25.887  1.000 17.087 0 119 LEU A O   1 ? 
ATOM   595  C CB  . LEU A 1 84  ? -21.875 -19.560 26.698  1.000 18.609 0 119 LEU A CB  1 ? 
ATOM   596  C CG  . LEU A 1 84  ? -22.444 -18.512 27.643  1.000 21.525 0 119 LEU A CG  1 ? 
ATOM   597  C CD1 . LEU A 1 84  ? -23.335 -17.577 26.856  1.000 21.429 0 119 LEU A CD1 1 ? 
ATOM   598  C CD2 . LEU A 1 84  ? -23.184 -19.169 28.823  1.000 23.049 0 119 LEU A CD2 1 ? 
ATOM   599  N N   . ASN A 1 85  ? -21.192 -22.511 25.789  1.000 15.913 0 120 ASN A N   1 ? 
ATOM   600  C CA  . ASN A 1 85  ? -20.991 -23.175 24.521  1.000 15.565 0 120 ASN A CA  1 ? 
ATOM   601  C C   . ASN A 1 85  ? -21.950 -22.547 23.515  1.000 17.587 0 120 ASN A C   1 ? 
ATOM   602  O O   . ASN A 1 85  ? -23.006 -22.023 23.895  1.000 18.381 0 120 ASN A O   1 ? 
ATOM   603  C CB  . ASN A 1 85  ? -21.246 -24.682 24.596  1.000 15.703 0 120 ASN A CB  1 ? 
ATOM   604  C CG  . ASN A 1 85  ? -20.477 -25.387 25.695  1.000 15.910 0 120 ASN A CG  1 ? 
ATOM   605  O OD1 . ASN A 1 85  ? -19.262 -25.225 25.818  1.000 15.586 0 120 ASN A OD1 1 ? 
ATOM   606  N ND2 . ASN A 1 85  ? -21.177 -26.181 26.488  1.000 14.675 0 120 ASN A ND2 1 ? 
ATOM   607  N N   . HIS A 1 86  ? -21.584 -22.645 22.231  1.000 18.011 0 121 HIS A N   1 ? 
ATOM   608  C CA  . HIS A 1 86  ? -22.342 -22.048 21.135  1.000 18.464 0 121 HIS A CA  1 ? 
ATOM   609  C C   . HIS A 1 86  ? -23.454 -22.988 20.673  1.000 20.043 0 121 HIS A C   1 ? 
ATOM   610  O O   . HIS A 1 86  ? -23.331 -24.189 20.854  1.000 21.728 0 121 HIS A O   1 ? 
ATOM   611  C CB  . HIS A 1 86  ? -21.399 -21.784 19.961  1.000 18.268 0 121 HIS A CB  1 ? 
ATOM   612  C CG  . HIS A 1 86  ? -20.328 -20.781 20.264  1.000 17.590 0 121 HIS A CG  1 ? 
ATOM   613  N ND1 . HIS A 1 86  ? -20.651 -19.498 20.661  1.000 17.593 0 121 HIS A ND1 1 ? 
ATOM   614  C CD2 . HIS A 1 86  ? -18.983 -20.829 20.243  1.000 17.545 0 121 HIS A CD2 1 ? 
ATOM   615  C CE1 . HIS A 1 86  ? -19.532 -18.791 20.851  1.000 18.301 0 121 HIS A CE1 1 ? 
ATOM   616  N NE2 . HIS A 1 86  ? -18.502 -19.589 20.622  1.000 17.223 0 121 HIS A NE2 1 ? 
ATOM   617  N N   . LEU A 1 87  ? -24.535 -22.456 20.094  1.000 18.482 0 122 LEU A N   1 ? 
ATOM   618  C CA  . LEU A 1 87  ? -25.454 -23.278 19.315  1.000 18.764 0 122 LEU A CA  1 ? 
ATOM   619  C C   . LEU A 1 87  ? -24.850 -23.519 17.938  1.000 19.073 0 122 LEU A C   1 ? 
ATOM   620  O O   . LEU A 1 87  ? -24.187 -22.644 17.382  1.000 16.575 0 122 LEU A O   1 ? 
ATOM   621  C CB  . LEU A 1 87  ? -26.790 -22.557 19.146  1.000 19.505 0 122 LEU A CB  1 ? 
ATOM   622  C CG  . LEU A 1 87  ? -27.540 -22.292 20.445  1.000 20.022 0 122 LEU A CG  1 ? 
ATOM   623  C CD1 . LEU A 1 87  ? -28.709 -21.349 20.207  1.000 20.732 0 122 LEU A CD1 1 ? 
ATOM   624  C CD2 . LEU A 1 87  ? -28.009 -23.584 21.104  1.000 20.802 0 122 LEU A CD2 1 ? 
ATOM   625  N N   . SER A 1 88  ? -25.124 -24.689 17.360  1.000 20.499 0 123 SER A N   1 ? 
ATOM   626  C CA  . SER A 1 88  ? -24.511 -25.038 16.090  1.000 23.239 0 123 SER A CA  1 ? 
ATOM   627  C C   . SER A 1 88  ? -25.008 -24.131 14.958  1.000 22.805 0 123 SER A C   1 ? 
ATOM   628  O O   . SER A 1 88  ? -24.302 -23.971 13.963  1.000 25.169 0 123 SER A O   1 ? 
ATOM   629  C CB  . SER A 1 88  ? -24.675 -26.501 15.789  1.000 24.133 0 123 SER A CB  1 ? 
ATOM   630  O OG  . SER A 1 88  ? -26.041 -26.856 15.842  1.000 31.858 0 123 SER A OG  1 ? 
ATOM   631  N N   . LYS A 1 89  ? -26.177 -23.479 15.116  1.000 24.524 0 124 LYS A N   1 ? 
ATOM   632  C CA  . LYS A 1 89  ? -26.694 -22.572 14.095  1.000 25.732 0 124 LYS A CA  1 ? 
ATOM   633  C C   . LYS A 1 89  ? -25.974 -21.219 14.104  1.000 23.118 0 124 LYS A C   1 ? 
ATOM   634  O O   . LYS A 1 89  ? -26.032 -20.484 13.127  1.000 23.966 0 124 LYS A O   1 ? 
ATOM   635  C CB  . LYS A 1 89  ? -28.201 -22.377 14.291  1.000 31.268 0 124 LYS A CB  1 ? 
ATOM   636  C CG  . LYS A 1 89  ? -29.041 -23.636 14.071  1.000 43.949 0 124 LYS A CG  1 ? 
ATOM   637  C CD  . LYS A 1 89  ? -30.378 -23.715 14.871  1.000 52.958 0 124 LYS A CD  1 ? 
ATOM   638  C CE  . LYS A 1 89  ? -31.427 -24.666 14.306  1.000 52.749 0 124 LYS A CE  1 ? 
ATOM   639  N NZ  . LYS A 1 89  ? -30.955 -26.069 14.142  1.000 50.439 0 124 LYS A NZ  1 ? 
ATOM   640  N N   . THR A 1 90  ? -25.341 -20.842 15.221  1.000 21.122 0 125 THR A N   1 ? 
ATOM   641  C CA  . THR A 1 90  ? -24.657 -19.559 15.331  1.000 20.115 0 125 THR A CA  1 ? 
ATOM   642  C C   . THR A 1 90  ? -23.678 -19.404 14.167  1.000 19.672 0 125 THR A C   1 ? 
ATOM   643  O O   . THR A 1 90  ? -23.037 -20.380 13.781  1.000 17.303 0 125 THR A O   1 ? 
ATOM   644  C CB  . THR A 1 90  ? -23.949 -19.461 16.690  1.000 19.631 0 125 THR A CB  1 ? 
ATOM   645  O OG1 . THR A 1 90  ? -25.023 -19.357 17.612  1.000 20.900 0 125 THR A OG1 1 ? 
ATOM   646  C CG2 . THR A 1 90  ? -22.995 -18.300 16.834  1.000 19.447 0 125 THR A CG2 1 ? 
ATOM   647  N N   . ASP A 1 91  ? -23.600 -18.195 13.588  1.000 20.836 0 126 ASP A N   1 ? 
ATOM   648  C CA  . ASP A 1 91  ? -22.665 -17.951 12.505  1.000 21.389 0 126 ASP A CA  1 ? 
ATOM   649  C C   . ASP A 1 91  ? -22.109 -16.531 12.465  1.000 21.449 0 126 ASP A C   1 ? 
ATOM   650  O O   . ASP A 1 91  ? -21.386 -16.241 11.507  1.000 20.944 0 126 ASP A O   1 ? 
ATOM   651  C CB  . ASP A 1 91  ? -23.266 -18.293 11.135  1.000 24.774 0 126 ASP A CB  1 ? 
ATOM   652  C CG  . ASP A 1 91  ? -24.459 -17.461 10.682  1.000 25.953 0 126 ASP A CG  1 ? 
ATOM   653  O OD1 . ASP A 1 91  ? -24.797 -16.502 11.365  1.000 27.653 0 126 ASP A OD1 1 ? 
ATOM   654  O OD2 . ASP A 1 91  ? -25.063 -17.815 9.649   1.000 31.467 0 126 ASP A OD2 1 ? 
ATOM   655  N N   . ASP A 1 92  ? -22.409 -15.675 13.466  1.000 20.269 0 127 ASP A N   1 ? 
ATOM   656  C CA  . ASP A 1 92  ? -21.831 -14.333 13.495  1.000 20.921 0 127 ASP A CA  1 ? 
ATOM   657  C C   . ASP A 1 92  ? -21.878 -13.756 14.909  1.000 19.007 0 127 ASP A C   1 ? 
ATOM   658  O O   . ASP A 1 92  ? -22.431 -14.377 15.815  1.000 17.908 0 127 ASP A O   1 ? 
ATOM   659  C CB  . ASP A 1 92  ? -22.472 -13.408 12.456  1.000 22.471 0 127 ASP A CB  1 ? 
ATOM   660  C CG  . ASP A 1 92  ? -23.958 -13.160 12.642  1.000 24.407 0 127 ASP A CG  1 ? 
ATOM   661  O OD1 . ASP A 1 92  ? -24.476 -13.391 13.759  1.000 23.708 0 127 ASP A OD1 1 ? 
ATOM   662  O OD2 . ASP A 1 92  ? -24.599 -12.804 11.634  1.000 24.136 0 127 ASP A OD2 1 ? 
ATOM   663  N N   . ALA A 1 93  ? -21.238 -12.593 15.106  1.000 18.263 0 128 ALA A N   1 ? 
ATOM   664  C CA  . ALA A 1 93  ? -21.129 -11.977 16.426  1.000 19.200 0 128 ALA A CA  1 ? 
ATOM   665  C C   . ALA A 1 93  ? -22.503 -11.620 16.990  1.000 19.634 0 128 ALA A C   1 ? 
ATOM   666  O O   . ALA A 1 93  ? -22.691 -11.668 18.207  1.000 17.843 0 128 ALA A O   1 ? 
ATOM   667  C CB  . ALA A 1 93  ? -20.251 -10.756 16.374  1.000 18.828 0 128 ALA A CB  1 ? 
ATOM   668  N N   . ASP A 1 94  ? -23.430 -11.224 16.107  1.000 20.180 0 129 ASP A N   1 ? 
ATOM   669  C CA  . ASP A 1 94  ? -24.808 -10.940 16.504  1.000 22.962 0 129 ASP A CA  1 ? 
ATOM   670  C C   . ASP A 1 94  ? -25.466 -12.154 17.176  1.000 20.206 0 129 ASP A C   1 ? 
ATOM   671  O O   . ASP A 1 94  ? -26.145 -12.006 18.184  1.000 18.293 0 129 ASP A O   1 ? 
ATOM   672  C CB  . ASP A 1 94  ? -25.671 -10.479 15.328  1.000 26.323 0 129 ASP A CB  1 ? 
ATOM   673  C CG  . ASP A 1 94  ? -25.700 -8.966  15.172  1.000 36.228 0 129 ASP A CG  1 ? 
ATOM   674  O OD1 . ASP A 1 94  ? -26.343 -8.274  16.051  1.000 43.356 0 129 ASP A OD1 1 ? 
ATOM   675  O OD2 . ASP A 1 94  ? -25.084 -8.483  14.182  1.000 44.040 0 129 ASP A OD2 1 ? 
ATOM   676  N N   . ALA A 1 95  ? -25.260 -13.351 16.619  1.000 18.554 0 130 ALA A N   1 ? 
ATOM   677  C CA  . ALA A 1 95  ? -25.825 -14.558 17.202  1.000 18.462 0 130 ALA A CA  1 ? 
ATOM   678  C C   . ALA A 1 95  ? -25.131 -14.860 18.533  1.000 18.092 0 130 ALA A C   1 ? 
ATOM   679  O O   . ALA A 1 95  ? -25.755 -15.411 19.440  1.000 14.963 0 130 ALA A O   1 ? 
ATOM   680  C CB  . ALA A 1 95  ? -25.716 -15.728 16.243  1.000 17.384 0 130 ALA A CB  1 ? 
ATOM   681  N N   . VAL A 1 96  ? -23.828 -14.532 18.640  1.000 17.105 0 131 VAL A N   1 ? 
ATOM   682  C CA  . VAL A 1 96  ? -23.130 -14.768 19.892  1.000 17.320 0 131 VAL A CA  1 ? 
ATOM   683  C C   . VAL A 1 96  ? -23.656 -13.808 20.958  1.000 16.938 0 131 VAL A C   1 ? 
ATOM   684  O O   . VAL A 1 96  ? -23.765 -14.188 22.118  1.000 16.655 0 131 VAL A O   1 ? 
ATOM   685  C CB  . VAL A 1 96  ? -21.599 -14.701 19.752  1.000 16.843 0 131 VAL A CB  1 ? 
ATOM   686  C CG1 . VAL A 1 96  ? -20.947 -14.933 21.110  1.000 15.993 0 131 VAL A CG1 1 ? 
ATOM   687  C CG2 . VAL A 1 96  ? -21.100 -15.718 18.745  1.000 15.852 0 131 VAL A CG2 1 ? 
ATOM   688  N N   . ALA A 1 97  ? -24.005 -12.580 20.574  1.000 16.705 0 132 ALA A N   1 ? 
ATOM   689  C CA  . ALA A 1 97  ? -24.613 -11.634 21.500  1.000 17.139 0 132 ALA A CA  1 ? 
ATOM   690  C C   . ALA A 1 97  ? -25.944 -12.188 22.014  1.000 17.501 0 132 ALA A C   1 ? 
ATOM   691  O O   . ALA A 1 97  ? -26.257 -12.010 23.183  1.000 17.032 0 132 ALA A O   1 ? 
ATOM   692  C CB  . ALA A 1 97  ? -24.803 -10.277 20.837  1.000 17.452 0 132 ALA A CB  1 ? 
ATOM   693  N N   . ASP A 1 98  ? -26.710 -12.873 21.152  1.000 18.519 0 133 ASP A N   1 ? 
ATOM   694  C CA  . ASP A 1 98  ? -27.938 -13.553 21.547  1.000 19.106 0 133 ASP A CA  1 ? 
ATOM   695  C C   . ASP A 1 98  ? -27.643 -14.663 22.552  1.000 17.789 0 133 ASP A C   1 ? 
ATOM   696  O O   . ASP A 1 98  ? -28.413 -14.837 23.482  1.000 15.273 0 133 ASP A O   1 ? 
ATOM   697  C CB  . ASP A 1 98  ? -28.666 -14.148 20.339  1.000 21.499 0 133 ASP A CB  1 ? 
ATOM   698  C CG  . ASP A 1 98  ? -29.233 -13.116 19.375  1.000 24.586 0 133 ASP A CG  1 ? 
ATOM   699  O OD1 . ASP A 1 98  ? -29.366 -11.950 19.779  1.000 27.380 0 133 ASP A OD1 1 ? 
ATOM   700  O OD2 . ASP A 1 98  ? -29.509 -13.472 18.216  1.000 28.199 0 133 ASP A OD2 1 ? 
ATOM   701  N N   . GLU A 1 99  ? -26.528 -15.398 22.357  1.000 15.934 0 134 GLU A N   1 ? 
ATOM   702  C CA  . GLU A 1 99  ? -26.148 -16.457 23.273  1.000 16.950 0 134 GLU A CA  1 ? 
ATOM   703  C C   . GLU A 1 99  ? -25.828 -15.865 24.645  1.000 16.089 0 134 GLU A C   1 ? 
ATOM   704  O O   . GLU A 1 99  ? -26.271 -16.396 25.647  1.000 14.405 0 134 GLU A O   1 ? 
ATOM   705  C CB  . GLU A 1 99  ? -24.947 -17.264 22.762  1.000 17.947 0 134 GLU A CB  1 ? 
ATOM   706  C CG  . GLU A 1 99  ? -25.232 -18.062 21.491  1.000 18.810 0 134 GLU A CG  1 ? 
ATOM   707  C CD  . GLU A 1 99  ? -24.013 -18.720 20.855  1.000 19.399 0 134 GLU A CD  1 ? 
ATOM   708  O OE1 . GLU A 1 99  ? -22.880 -18.322 21.196  1.000 20.635 0 134 GLU A OE1 1 ? 
ATOM   709  O OE2 . GLU A 1 99  ? -24.193 -19.638 20.032  1.000 20.288 0 134 GLU A OE2 1 ? 
ATOM   710  N N   . LEU A 1 100 ? -25.011 -14.807 24.674  1.000 15.812 0 135 LEU A N   1 ? 
ATOM   711  C CA  . LEU A 1 100 ? -24.648 -14.105 25.890  1.000 16.374 0 135 LEU A CA  1 ? 
ATOM   712  C C   . LEU A 1 100 ? -25.884 -13.579 26.606  1.000 15.886 0 135 LEU A C   1 ? 
ATOM   713  O O   . LEU A 1 100 ? -25.958 -13.705 27.824  1.000 17.775 0 135 LEU A O   1 ? 
ATOM   714  C CB  . LEU A 1 100 ? -23.714 -12.942 25.553  1.000 16.624 0 135 LEU A CB  1 ? 
ATOM   715  C CG  . LEU A 1 100 ? -22.284 -13.337 25.188  1.000 17.023 0 135 LEU A CG  1 ? 
ATOM   716  C CD1 . LEU A 1 100 ? -21.571 -12.129 24.589  1.000 17.717 0 135 LEU A CD1 1 ? 
ATOM   717  C CD2 . LEU A 1 100 ? -21.552 -13.873 26.399  1.000 16.603 0 135 LEU A CD2 1 ? 
ATOM   718  N N   . ALA A 1 101 ? -26.814 -12.958 25.868  1.000 16.035 0 136 ALA A N   1 ? 
ATOM   719  C CA  . ALA A 1 101 ? -28.051 -12.486 26.477  1.000 16.950 0 136 ALA A CA  1 ? 
ATOM   720  C C   . ALA A 1 101 ? -28.817 -13.640 27.127  1.000 16.558 0 136 ALA A C   1 ? 
ATOM   721  O O   . ALA A 1 101 ? -29.327 -13.494 28.231  1.000 14.879 0 136 ALA A O   1 ? 
ATOM   722  C CB  . ALA A 1 101 ? -28.900 -11.762 25.466  1.000 17.944 0 136 ALA A CB  1 ? 
ATOM   723  N N   . ALA A 1 102 ? -28.902 -14.789 26.439  1.000 16.438 0 137 ALA A N   1 ? 
ATOM   724  C CA  . ALA A 1 102 ? -29.615 -15.948 26.957  1.000 16.496 0 137 ALA A CA  1 ? 
ATOM   725  C C   . ALA A 1 102 ? -28.891 -16.515 28.183  1.000 16.899 0 137 ALA A C   1 ? 
ATOM   726  O O   . ALA A 1 102 ? -29.529 -16.878 29.163  1.000 18.378 0 137 ALA A O   1 ? 
ATOM   727  C CB  . ALA A 1 102 ? -29.789 -16.973 25.865  1.000 16.847 0 137 ALA A CB  1 ? 
ATOM   728  N N   . GLY A 1 103 ? -27.553 -16.546 28.148  1.000 17.000 0 138 GLY A N   1 ? 
ATOM   729  C CA  . GLY A 1 103 ? -26.728 -16.959 29.270  1.000 16.153 0 138 GLY A CA  1 ? 
ATOM   730  C C   . GLY A 1 103 ? -26.903 -16.074 30.509  1.000 16.320 0 138 GLY A C   1 ? 
ATOM   731  O O   . GLY A 1 103 ? -26.977 -16.589 31.625  1.000 15.413 0 138 GLY A O   1 ? 
ATOM   732  N N   . LEU A 1 104 ? -26.952 -14.753 30.312  1.000 17.332 0 139 LEU A N   1 ? 
ATOM   733  C CA  . LEU A 1 104 ? -27.190 -13.821 31.417  1.000 19.527 0 139 LEU A CA  1 ? 
ATOM   734  C C   . LEU A 1 104 ? -28.540 -14.081 32.074  1.000 19.334 0 139 LEU A C   1 ? 
ATOM   735  O O   . LEU A 1 104 ? -28.638 -14.153 33.294  1.000 16.951 0 139 LEU A O   1 ? 
ATOM   736  C CB  . LEU A 1 104 ? -27.145 -12.370 30.929  1.000 20.561 0 139 LEU A CB  1 ? 
ATOM   737  C CG  . LEU A 1 104 ? -25.737 -11.816 30.721  1.000 24.498 0 139 LEU A CG  1 ? 
ATOM   738  C CD1 . LEU A 1 104 ? -25.792 -10.640 29.761  1.000 24.736 0 139 LEU A CD1 1 ? 
ATOM   739  C CD2 . LEU A 1 104 ? -25.090 -11.418 32.044  1.000 25.052 0 139 LEU A CD2 1 ? 
ATOM   740  N N   . GLU A 1 105 ? -29.566 -14.203 31.237  1.000 19.967 0 140 GLU A N   1 ? 
ATOM   741  C CA  . GLU A 1 105 ? -30.919 -14.381 31.731  1.000 22.445 0 140 GLU A CA  1 ? 
ATOM   742  C C   . GLU A 1 105 ? -31.013 -15.710 32.466  1.000 20.446 0 140 GLU A C   1 ? 
ATOM   743  O O   . GLU A 1 105 ? -31.595 -15.761 33.546  1.000 19.533 0 140 GLU A O   1 ? 
ATOM   744  C CB  . GLU A 1 105 ? -31.925 -14.299 30.584  1.000 27.682 0 140 GLU A CB  1 ? 
ATOM   745  C CG  . GLU A 1 105 ? -33.235 -14.984 30.909  1.000 35.429 0 140 GLU A CG  1 ? 
ATOM   746  C CD  . GLU A 1 105 ? -34.408 -14.308 30.236  1.000 45.249 0 140 GLU A CD  1 ? 
ATOM   747  O OE1 . GLU A 1 105 ? -34.394 -14.207 28.977  1.000 48.855 0 140 GLU A OE1 1 ? 
ATOM   748  O OE2 . GLU A 1 105 ? -35.298 -13.842 30.984  1.000 53.812 0 140 GLU A OE2 1 ? 
ATOM   749  N N   . TYR A 1 106 ? -30.387 -16.762 31.911  1.000 18.658 0 141 TYR A N   1 ? 
ATOM   750  C CA  . TYR A 1 106 ? -30.350 -18.055 32.557  1.000 17.118 0 141 TYR A CA  1 ? 
ATOM   751  C C   . TYR A 1 106 ? -29.704 -17.910 33.921  1.000 17.049 0 141 TYR A C   1 ? 
ATOM   752  O O   . TYR A 1 106 ? -30.236 -18.411 34.895  1.000 17.323 0 141 TYR A O   1 ? 
ATOM   753  C CB  . TYR A 1 106 ? -29.624 -19.111 31.713  1.000 17.039 0 141 TYR A CB  1 ? 
ATOM   754  C CG  . TYR A 1 106 ? -29.428 -20.406 32.465  1.000 18.421 0 141 TYR A CG  1 ? 
ATOM   755  C CD1 . TYR A 1 106 ? -30.424 -21.372 32.522  1.000 18.183 0 141 TYR A CD1 1 ? 
ATOM   756  C CD2 . TYR A 1 106 ? -28.276 -20.623 33.199  1.000 17.918 0 141 TYR A CD2 1 ? 
ATOM   757  C CE1 . TYR A 1 106 ? -30.259 -22.531 33.259  1.000 19.889 0 141 TYR A CE1 1 ? 
ATOM   758  C CE2 . TYR A 1 106 ? -28.090 -21.791 33.915  1.000 17.882 0 141 TYR A CE2 1 ? 
ATOM   759  C CZ  . TYR A 1 106 ? -29.083 -22.748 33.950  1.000 18.724 0 141 TYR A CZ  1 ? 
ATOM   760  O OH  . TYR A 1 106 ? -28.899 -23.900 34.696  1.000 19.727 0 141 TYR A OH  1 ? 
ATOM   761  N N   . LEU A 1 107 ? -28.544 -17.253 33.987  1.000 16.942 0 142 LEU A N   1 ? 
ATOM   762  C CA  . LEU A 1 107 ? -27.756 -17.258 35.203  1.000 17.706 0 142 LEU A CA  1 ? 
ATOM   763  C C   . LEU A 1 107 ? -28.537 -16.581 36.326  1.000 17.926 0 142 LEU A C   1 ? 
ATOM   764  O O   . LEU A 1 107 ? -28.527 -17.053 37.469  1.000 18.208 0 142 LEU A O   1 ? 
ATOM   765  C CB  . LEU A 1 107 ? -26.409 -16.568 34.944  1.000 17.816 0 142 LEU A CB  1 ? 
ATOM   766  C CG  . LEU A 1 107 ? -25.454 -16.508 36.136  1.000 18.109 0 142 LEU A CG  1 ? 
ATOM   767  C CD1 . LEU A 1 107 ? -25.058 -17.897 36.611  1.000 19.526 0 142 LEU A CD1 1 ? 
ATOM   768  C CD2 . LEU A 1 107 ? -24.222 -15.699 35.795  1.000 18.728 0 142 LEU A CD2 1 ? 
ATOM   769  N N   . LYS A 1 108 ? -29.194 -15.476 35.977  1.000 18.999 0 143 LYS A N   1 ? 
ATOM   770  C CA  . LYS A 1 108 ? -29.908 -14.645 36.927  1.000 21.234 0 143 LYS A CA  1 ? 
ATOM   771  C C   . LYS A 1 108 ? -31.201 -15.300 37.390  1.000 21.598 0 143 LYS A C   1 ? 
ATOM   772  O O   . LYS A 1 108 ? -31.525 -15.187 38.561  1.000 22.127 0 143 LYS A O   1 ? 
ATOM   773  C CB  . LYS A 1 108 ? -30.198 -13.277 36.307  1.000 22.671 0 143 LYS A CB  1 ? 
ATOM   774  C CG  . LYS A 1 108 ? -28.971 -12.392 36.138  1.000 23.708 0 143 LYS A CG  1 ? 
ATOM   775  C CD  . LYS A 1 108 ? -29.345 -10.985 35.788  1.000 26.619 0 143 LYS A CD  1 ? 
ATOM   776  C CE  . LYS A 1 108 ? -29.688 -10.842 34.329  1.000 29.314 0 143 LYS A CE  1 ? 
ATOM   777  N NZ  . LYS A 1 108 ? -30.093 -9.446  34.020  1.000 32.385 0 143 LYS A NZ  1 ? 
ATOM   778  N N   . THR A 1 109 ? -31.932 -15.987 36.499  1.000 22.642 0 144 THR A N   1 ? 
ATOM   779  C CA  . THR A 1 109 ? -33.316 -16.328 36.807  1.000 22.416 0 144 THR A CA  1 ? 
ATOM   780  C C   . THR A 1 109 ? -33.603 -17.827 36.763  1.000 23.820 0 144 THR A C   1 ? 
ATOM   781  O O   . THR A 1 109 ? -34.593 -18.242 37.361  1.000 26.284 0 144 THR A O   1 ? 
ATOM   782  C CB  . THR A 1 109 ? -34.279 -15.593 35.865  1.000 22.953 0 144 THR A CB  1 ? 
ATOM   783  O OG1 . THR A 1 109 ? -34.101 -16.108 34.544  1.000 23.439 0 144 THR A OG1 1 ? 
ATOM   784  C CG2 . THR A 1 109 ? -34.063 -14.094 35.840  1.000 23.792 0 144 THR A CG2 1 ? 
ATOM   785  N N   . LYS A 1 110 ? -32.813 -18.646 36.048  1.000 23.365 0 145 LYS A N   1 ? 
ATOM   786  C CA  . LYS A 1 110 ? -33.184 -20.042 35.846  1.000 24.244 0 145 LYS A CA  1 ? 
ATOM   787  C C   . LYS A 1 110 ? -32.082 -21.003 36.299  1.000 21.901 0 145 LYS A C   1 ? 
ATOM   788  O O   . LYS A 1 110 ? -32.245 -22.204 36.177  1.000 22.187 0 145 LYS A O   1 ? 
ATOM   789  C CB  . LYS A 1 110 ? -33.467 -20.354 34.372  1.000 29.997 0 145 LYS A CB  1 ? 
ATOM   790  C CG  . LYS A 1 110 ? -34.359 -19.384 33.600  1.000 35.469 0 145 LYS A CG  1 ? 
ATOM   791  C CD  . LYS A 1 110 ? -34.740 -19.924 32.221  1.000 43.277 0 145 LYS A CD  1 ? 
ATOM   792  C CE  . LYS A 1 110 ? -34.563 -18.939 31.078  1.000 46.907 0 145 LYS A CE  1 ? 
ATOM   793  N NZ  . LYS A 1 110 ? -35.727 -18.030 30.955  1.000 45.602 0 145 LYS A NZ  1 ? 
ATOM   794  N N   . SER A 1 111 ? -30.940 -20.498 36.772  1.000 20.014 0 146 SER A N   1 ? 
ATOM   795  C CA  . SER A 1 111 ? -29.875 -21.345 37.289  1.000 19.283 0 146 SER A CA  1 ? 
ATOM   796  C C   . SER A 1 111 ? -30.334 -22.022 38.582  1.000 19.133 0 146 SER A C   1 ? 
ATOM   797  O O   . SER A 1 111 ? -31.293 -21.560 39.199  1.000 19.591 0 146 SER A O   1 ? 
ATOM   798  C CB  . SER A 1 111 ? -28.621 -20.532 37.472  1.000 18.270 0 146 SER A CB  1 ? 
ATOM   799  O OG  . SER A 1 111 ? -28.822 -19.439 38.376  1.000 17.080 0 146 SER A OG  1 ? 
ATOM   800  N N   . PRO A 1 112 ? -29.713 -23.127 39.033  1.000 18.602 0 147 PRO A N   1 ? 
ATOM   801  C CA  . PRO A 1 112 ? -30.068 -23.723 40.323  1.000 20.107 0 147 PRO A CA  1 ? 
ATOM   802  C C   . PRO A 1 112 ? -30.002 -22.733 41.485  1.000 20.244 0 147 PRO A C   1 ? 
ATOM   803  O O   . PRO A 1 112 ? -29.212 -21.776 41.475  1.000 22.278 0 147 PRO A O   1 ? 
ATOM   804  C CB  . PRO A 1 112 ? -29.039 -24.859 40.533  1.000 20.145 0 147 PRO A CB  1 ? 
ATOM   805  C CG  . PRO A 1 112 ? -28.490 -25.167 39.141  1.000 19.383 0 147 PRO A CG  1 ? 
ATOM   806  C CD  . PRO A 1 112 ? -28.689 -23.913 38.317  1.000 19.616 0 147 PRO A CD  1 ? 
ATOM   807  N N   . ALA A 1 113 ? -30.859 -22.982 42.473  1.000 18.431 0 148 ALA A N   1 ? 
ATOM   808  C CA  . ALA A 1 113 ? -30.895 -22.227 43.713  1.000 20.774 0 148 ALA A CA  1 ? 
ATOM   809  C C   . ALA A 1 113 ? -29.499 -22.014 44.306  1.000 21.189 0 148 ALA A C   1 ? 
ATOM   810  O O   . ALA A 1 113 ? -29.190 -20.929 44.793  1.000 20.763 0 148 ALA A O   1 ? 
ATOM   811  C CB  . ALA A 1 113 ? -31.809 -22.932 44.678  1.000 21.578 0 148 ALA A CB  1 ? 
ATOM   812  N N   . GLU A 1 114 ? -28.640 -23.034 44.245  1.000 20.045 0 149 GLU A N   1 ? 
ATOM   813  C CA  . GLU A 1 114 ? -27.298 -22.944 44.798  1.000 20.263 0 149 GLU A CA  1 ? 
ATOM   814  C C   . GLU A 1 114 ? -26.475 -21.874 44.078  1.000 20.379 0 149 GLU A C   1 ? 
ATOM   815  O O   . GLU A 1 114 ? -25.634 -21.218 44.698  1.000 18.879 0 149 GLU A O   1 ? 
ATOM   816  C CB  . GLU A 1 114 ? -26.580 -24.293 44.695  1.000 20.549 0 149 GLU A CB  1 ? 
ATOM   817  C CG  . GLU A 1 114 ? -27.247 -25.391 45.506  1.000 21.536 0 149 GLU A CG  1 ? 
ATOM   818  C CD  . GLU A 1 114 ? -28.398 -26.128 44.845  1.000 22.451 0 149 GLU A CD  1 ? 
ATOM   819  O OE1 . GLU A 1 114 ? -28.940 -25.623 43.825  1.000 20.999 0 149 GLU A OE1 1 ? 
ATOM   820  O OE2 . GLU A 1 114 ? -28.759 -27.206 45.372  1.000 24.426 0 149 GLU A OE2 1 ? 
ATOM   821  N N   . VAL A 1 115 ? -26.688 -21.732 42.763  1.000 20.625 0 150 VAL A N   1 ? 
ATOM   822  C CA  . VAL A 1 115 ? -25.961 -20.739 41.981  1.000 20.881 0 150 VAL A CA  1 ? 
ATOM   823  C C   . VAL A 1 115 ? -26.540 -19.357 42.281  1.000 19.647 0 150 VAL A C   1 ? 
ATOM   824  O O   . VAL A 1 115 ? -25.793 -18.409 42.488  1.000 20.276 0 150 VAL A O   1 ? 
ATOM   825  C CB  . VAL A 1 115 ? -25.989 -21.034 40.466  1.000 21.613 0 150 VAL A CB  1 ? 
ATOM   826  C CG1 . VAL A 1 115 ? -25.340 -19.897 39.681  1.000 23.069 0 150 VAL A CG1 1 ? 
ATOM   827  C CG2 . VAL A 1 115 ? -25.346 -22.369 40.119  1.000 21.825 0 150 VAL A CG2 1 ? 
ATOM   828  N N   . GLN A 1 116 ? -27.866 -19.238 42.261  1.000 19.034 0 151 GLN A N   1 ? 
ATOM   829  C CA  . GLN A 1 116 ? -28.520 -17.974 42.559  1.000 21.154 0 151 GLN A CA  1 ? 
ATOM   830  C C   . GLN A 1 116 ? -28.136 -17.477 43.951  1.000 22.402 0 151 GLN A C   1 ? 
ATOM   831  O O   . GLN A 1 116 ? -27.963 -16.268 44.124  1.000 24.386 0 151 GLN A O   1 ? 
ATOM   832  C CB  . GLN A 1 116 ? -30.035 -18.075 42.365  1.000 21.205 0 151 GLN A CB  1 ? 
ATOM   833  C CG  . GLN A 1 116 ? -30.414 -18.271 40.904  1.000 21.385 0 151 GLN A CG  1 ? 
ATOM   834  C CD  . GLN A 1 116 ? -31.904 -18.181 40.681  1.000 22.735 0 151 GLN A CD  1 ? 
ATOM   835  O OE1 . GLN A 1 116 ? -32.574 -17.323 41.238  1.000 26.953 0 151 GLN A OE1 1 ? 
ATOM   836  N NE2 . GLN A 1 116 ? -32.445 -19.067 39.866  1.000 24.043 0 151 GLN A NE2 1 ? 
ATOM   837  N N   . ALA A 1 117 ? -27.954 -18.394 44.922  1.000 23.226 0 152 ALA A N   1 ? 
ATOM   838  C CA  . ALA A 1 117 ? -27.540 -18.034 46.279  1.000 23.775 0 152 ALA A CA  1 ? 
ATOM   839  C C   . ALA A 1 117 ? -26.195 -17.304 46.279  1.000 23.346 0 152 ALA A C   1 ? 
ATOM   840  O O   . ALA A 1 117 ? -25.977 -16.388 47.073  1.000 21.284 0 152 ALA A O   1 ? 
ATOM   841  C CB  . ALA A 1 117 ? -27.477 -19.264 47.163  1.000 23.264 0 152 ALA A CB  1 ? 
ATOM   842  N N   . ARG A 1 118 ? -25.300 -17.717 45.372  1.000 20.917 0 153 ARG A N   1 ? 
ATOM   843  C CA  . ARG A 1 118 ? -23.961 -17.166 45.302  1.000 20.648 0 153 ARG A CA  1 ? 
ATOM   844  C C   . ARG A 1 118 ? -23.941 -15.860 44.497  1.000 19.414 0 153 ARG A C   1 ? 
ATOM   845  O O   . ARG A 1 118 ? -22.942 -15.137 44.509  1.000 19.622 0 153 ARG A O   1 ? 
ATOM   846  C CB  . ARG A 1 118 ? -23.071 -18.257 44.678  1.000 22.822 0 153 ARG A CB  1 ? 
ATOM   847  C CG  . ARG A 1 118 ? -21.630 -18.302 45.144  1.000 23.441 0 153 ARG A CG  1 ? 
ATOM   848  C CD  . ARG A 1 118 ? -21.418 -18.251 46.649  1.000 25.263 0 153 ARG A CD  1 ? 
ATOM   849  N NE  . ARG A 1 118 ? -22.111 -19.292 47.353  1.000 27.790 0 153 ARG A NE  1 ? 
ATOM   850  C CZ  . ARG A 1 118 ? -23.026 -19.109 48.289  1.000 27.987 0 153 ARG A CZ  1 ? 
ATOM   851  N NH1 . ARG A 1 118 ? -23.382 -17.898 48.669  1.000 28.971 0 153 ARG A NH1 1 ? 
ATOM   852  N NH2 . ARG A 1 118 ? -23.574 -20.168 48.844  1.000 27.450 0 153 ARG A NH2 1 ? 
ATOM   853  N N   . LEU A 1 119 ? -25.036 -15.564 43.783  1.000 17.147 0 154 LEU A N   1 ? 
ATOM   854  C CA  . LEU A 1 119 ? -25.028 -14.498 42.796  1.000 16.828 0 154 LEU A CA  1 ? 
ATOM   855  C C   . LEU A 1 119 ? -25.699 -13.235 43.330  1.000 19.414 0 154 LEU A C   1 ? 
ATOM   856  O O   . LEU A 1 119 ? -26.801 -13.275 43.881  1.000 18.853 0 154 LEU A O   1 ? 
ATOM   857  C CB  . LEU A 1 119 ? -25.758 -15.017 41.552  1.000 16.285 0 154 LEU A CB  1 ? 
ATOM   858  C CG  . LEU A 1 119 ? -25.865 -14.009 40.407  1.000 15.769 0 154 LEU A CG  1 ? 
ATOM   859  C CD1 . LEU A 1 119 ? -24.521 -13.833 39.713  1.000 15.463 0 154 LEU A CD1 1 ? 
ATOM   860  C CD2 . LEU A 1 119 ? -26.917 -14.417 39.423  1.000 15.872 0 154 LEU A CD2 1 ? 
ATOM   861  N N   . ASP A 1 120 ? -25.057 -12.089 43.085  1.000 19.986 0 155 ASP A N   1 ? 
ATOM   862  C CA  . ASP A 1 120 ? -25.700 -10.789 43.191  1.000 19.444 0 155 ASP A CA  1 ? 
ATOM   863  C C   . ASP A 1 120 ? -26.071 -10.319 41.785  1.000 19.779 0 155 ASP A C   1 ? 
ATOM   864  O O   . ASP A 1 120 ? -25.252 -9.744  41.071  1.000 16.955 0 155 ASP A O   1 ? 
ATOM   865  C CB  . ASP A 1 120 ? -24.773 -9.778  43.873  1.000 19.532 0 155 ASP A CB  1 ? 
ATOM   866  C CG  . ASP A 1 120 ? -25.329 -8.367  43.954  1.000 20.873 0 155 ASP A CG  1 ? 
ATOM   867  O OD1 . ASP A 1 120 ? -26.446 -8.125  43.455  1.000 22.163 0 155 ASP A OD1 1 ? 
ATOM   868  O OD2 . ASP A 1 120 ? -24.647 -7.521  44.544  1.000 22.651 0 155 ASP A OD2 1 ? 
ATOM   869  N N   . ALA A 1 121 ? -27.331 -10.534 41.412  1.000 20.377 0 156 ALA A N   1 ? 
ATOM   870  C CA  . ALA A 1 121 ? -27.802 -10.341 40.047  1.000 19.771 0 156 ALA A CA  1 ? 
ATOM   871  C C   . ALA A 1 121 ? -27.896 -8.858  39.691  1.000 18.752 0 156 ALA A C   1 ? 
ATOM   872  O O   . ALA A 1 121 ? -28.140 -8.530  38.544  1.000 19.935 0 156 ALA A O   1 ? 
ATOM   873  C CB  . ALA A 1 121 ? -29.146 -11.021 39.883  1.000 21.305 0 156 ALA A CB  1 ? 
ATOM   874  N N   . SER A 1 122 ? -27.679 -7.962  40.661  1.000 18.906 0 157 SER A N   1 ? 
ATOM   875  C CA  . SER A 1 122 ? -27.725 -6.537  40.405  1.000 20.177 0 157 SER A CA  1 ? 
ATOM   876  C C   . SER A 1 122 ? -26.390 -6.059  39.835  1.000 20.466 0 157 SER A C   1 ? 
ATOM   877  O O   . SER A 1 122 ? -26.286 -4.929  39.380  1.000 22.496 0 157 SER A O   1 ? 
ATOM   878  C CB  . SER A 1 122 ? -28.098 -5.770  41.663  1.000 20.497 0 157 SER A CB  1 ? 
ATOM   879  O OG  . SER A 1 122 ? -26.981 -5.657  42.535  1.000 22.538 0 157 SER A OG  1 ? 
ATOM   880  N N   . ARG A 1 123 ? -25.360 -6.916  39.840  1.000 19.480 0 158 ARG A N   1 ? 
ATOM   881  C CA  . ARG A 1 123 ? -24.038 -6.540  39.369  1.000 18.628 0 158 ARG A CA  1 ? 
ATOM   882  C C   . ARG A 1 123 ? -23.553 -7.591  38.367  1.000 17.148 0 158 ARG A C   1 ? 
ATOM   883  O O   . ARG A 1 123 ? -23.139 -8.681  38.774  1.000 15.514 0 158 ARG A O   1 ? 
ATOM   884  C CB  . ARG A 1 123 ? -23.103 -6.420  40.574  1.000 20.414 0 158 ARG A CB  1 ? 
ATOM   885  C CG  . ARG A 1 123 ? -23.438 -5.276  41.517  1.000 23.039 0 158 ARG A CG  1 ? 
ATOM   886  C CD  . ARG A 1 123 ? -22.730 -5.442  42.852  1.000 27.424 0 158 ARG A CD  1 ? 
ATOM   887  N NE  . ARG A 1 123 ? -22.972 -4.317  43.752  1.000 31.337 0 158 ARG A NE  1 ? 
ATOM   888  C CZ  . ARG A 1 123 ? -22.395 -3.123  43.661  1.000 35.347 0 158 ARG A CZ  1 ? 
ATOM   889  N NH1 . ARG A 1 123 ? -21.402 -2.902  42.817  1.000 36.028 0 158 ARG A NH1 1 ? 
ATOM   890  N NH2 . ARG A 1 123 ? -22.809 -2.148  44.446  1.000 38.201 0 158 ARG A NH2 1 ? 
ATOM   891  N N   . MET A 1 124 ? -23.636 -7.267  37.068  1.000 16.300 0 159 MET A N   1 ? 
ATOM   892  C CA  . MET A 1 124 ? -23.387 -8.250  36.018  1.000 16.556 0 159 MET A CA  1 ? 
ATOM   893  C C   . MET A 1 124 ? -22.456 -7.666  34.955  1.000 17.172 0 159 MET A C   1 ? 
ATOM   894  O O   . MET A 1 124 ? -22.622 -6.514  34.554  1.000 15.327 0 159 MET A O   1 ? 
ATOM   895  C CB  . MET A 1 124 ? -24.684 -8.696  35.322  1.000 17.641 0 159 MET A CB  1 ? 
ATOM   896  C CG  . MET A 1 124 ? -25.712 -9.306  36.239  1.000 17.892 0 159 MET A CG  1 ? 
ATOM   897  S SD  . MET A 1 124 ? -25.220 -10.824 37.115  1.000 20.226 0 159 MET A SD  1 ? 
ATOM   898  C CE  . MET A 1 124 ? -25.268 -11.944 35.722  1.000 18.728 0 159 MET A CE  1 ? 
ATOM   899  N N   . GLY A 1 125 ? -21.471 -8.483  34.527  1.000 15.170 0 160 GLY A N   1 ? 
ATOM   900  C CA  . GLY A 1 125 ? -20.619 -8.150  33.399  1.000 16.153 0 160 GLY A CA  1 ? 
ATOM   901  C C   . GLY A 1 125 ? -20.575 -9.263  32.346  1.000 15.840 0 160 GLY A C   1 ? 
ATOM   902  O O   . GLY A 1 125 ? -21.121 -10.349 32.533  1.000 15.988 0 160 GLY A O   1 ? 
ATOM   903  N N   . VAL A 1 126 ? -19.930 -8.947  31.223  1.000 16.568 0 161 VAL A N   1 ? 
ATOM   904  C CA  A VAL A 1 126 ? -19.773 -9.862  30.101  0.500 16.515 0 161 VAL A CA  1 ? 
ATOM   905  C CA  B VAL A 1 126 ? -19.785 -9.841  30.084  0.500 16.957 0 161 VAL A CA  1 ? 
ATOM   906  C C   . VAL A 1 126 ? -18.332 -9.811  29.612  1.000 16.137 0 161 VAL A C   1 ? 
ATOM   907  O O   . VAL A 1 126 ? -17.669 -8.782  29.756  1.000 15.578 0 161 VAL A O   1 ? 
ATOM   908  C CB  A VAL A 1 126 ? -20.718 -9.561  28.916  0.500 16.645 0 161 VAL A CB  1 ? 
ATOM   909  C CB  B VAL A 1 126 ? -20.752 -9.413  28.959  0.500 17.700 0 161 VAL A CB  1 ? 
ATOM   910  C CG1 A VAL A 1 126 ? -22.104 -10.142 29.156  0.500 18.060 0 161 VAL A CG1 1 ? 
ATOM   911  C CG1 B VAL A 1 126 ? -20.608 -10.216 27.678  0.500 17.912 0 161 VAL A CG1 1 ? 
ATOM   912  C CG2 A VAL A 1 126 ? -20.780 -8.081  28.569  0.500 15.897 0 161 VAL A CG2 1 ? 
ATOM   913  C CG2 B VAL A 1 126 ? -22.191 -9.468  29.455  0.500 19.055 0 161 VAL A CG2 1 ? 
ATOM   914  N N   . ALA A 1 127 ? -17.894 -10.930 29.004  1.000 15.108 0 162 ALA A N   1 ? 
ATOM   915  C CA  . ALA A 1 127 ? -16.608 -11.051 28.346  1.000 14.580 0 162 ALA A CA  1 ? 
ATOM   916  C C   . ALA A 1 127 ? -16.736 -12.040 27.189  1.000 15.665 0 162 ALA A C   1 ? 
ATOM   917  O O   . ALA A 1 127 ? -17.668 -12.845 27.135  1.000 15.626 0 162 ALA A O   1 ? 
ATOM   918  C CB  . ALA A 1 127 ? -15.546 -11.487 29.325  1.000 15.046 0 162 ALA A CB  1 ? 
ATOM   919  N N   . GLY A 1 128 ? -15.802 -11.955 26.243  1.000 15.924 0 163 GLY A N   1 ? 
ATOM   920  C CA  . GLY A 1 128 ? -15.796 -12.903 25.148  1.000 16.508 0 163 GLY A CA  1 ? 
ATOM   921  C C   . GLY A 1 128 ? -14.518 -12.815 24.326  1.000 16.771 0 163 GLY A C   1 ? 
ATOM   922  O O   . GLY A 1 128 ? -13.870 -11.764 24.274  1.000 16.687 0 163 GLY A O   1 ? 
ATOM   923  N N   . HIS A 1 129 ? -14.208 -13.935 23.657  1.000 16.046 0 164 HIS A N   1 ? 
ATOM   924  C CA  . HIS A 1 129 ? -13.019 -14.053 22.842  1.000 15.780 0 164 HIS A CA  1 ? 
ATOM   925  C C   . HIS A 1 129 ? -13.408 -14.048 21.366  1.000 16.804 0 164 HIS A C   1 ? 
ATOM   926  O O   . HIS A 1 129 ? -14.349 -14.750 20.976  1.000 15.804 0 164 HIS A O   1 ? 
ATOM   927  C CB  . HIS A 1 129 ? -12.253 -15.320 23.249  1.000 16.008 0 164 HIS A CB  1 ? 
ATOM   928  C CG  . HIS A 1 129 ? -11.023 -15.499 22.458  1.000 16.754 0 164 HIS A CG  1 ? 
ATOM   929  N ND1 . HIS A 1 129 ? -10.577 -16.720 21.980  1.000 17.116 0 164 HIS A ND1 1 ? 
ATOM   930  C CD2 . HIS A 1 129 ? -10.144 -14.570 22.045  1.000 16.442 0 164 HIS A CD2 1 ? 
ATOM   931  C CE1 . HIS A 1 129 ? -9.457  -16.532 21.320  1.000 16.521 0 164 HIS A CE1 1 ? 
ATOM   932  N NE2 . HIS A 1 129 ? -9.176  -15.235 21.337  1.000 16.521 0 164 HIS A NE2 1 ? 
ATOM   933  N N   . SER A 1 130 ? -12.686 -13.238 20.565  1.000 16.215 0 165 SER A N   1 ? 
ATOM   934  C CA  . SER A 1 130 ? -12.732 -13.350 19.112  1.000 16.174 0 165 SER A CA  1 ? 
ATOM   935  C C   . SER A 1 130 ? -14.133 -12.962 18.640  1.000 16.870 0 165 SER A C   1 ? 
ATOM   936  O O   . SER A 1 130 ? -14.573 -11.845 18.907  1.000 17.945 0 165 SER A O   1 ? 
ATOM   937  C CB  . SER A 1 130 ? -12.262 -14.746 18.691  1.000 15.596 0 165 SER A CB  1 ? 
ATOM   938  O OG  . SER A 1 130 ? -12.201 -14.903 17.272  1.000 16.060 0 165 SER A OG  1 ? 
ATOM   939  N N   . MET A 1 131 ? -14.858 -13.859 17.968  1.000 16.591 0 166 MET A N   1 ? 
ATOM   940  C CA  . MET A 1 131 ? -16.241 -13.559 17.621  1.000 17.179 0 166 MET A CA  1 ? 
ATOM   941  C C   . MET A 1 131 ? -17.070 -13.313 18.897  1.000 17.295 0 166 MET A C   1 ? 
ATOM   942  O O   . MET A 1 131 ? -18.000 -12.499 18.906  1.000 17.365 0 166 MET A O   1 ? 
ATOM   943  C CB  . MET A 1 131 ? -16.848 -14.704 16.809  1.000 17.300 0 166 MET A CB  1 ? 
ATOM   944  C CG  . MET A 1 131 ? -18.243 -14.391 16.274  1.000 18.426 0 166 MET A CG  1 ? 
ATOM   945  S SD  . MET A 1 131 ? -18.997 -15.762 15.389  1.000 18.873 0 166 MET A SD  1 ? 
ATOM   946  C CE  . MET A 1 131 ? -18.025 -15.815 13.881  1.000 18.502 0 166 MET A CE  1 ? 
ATOM   947  N N   . GLY A 1 132 ? -16.709 -14.000 19.988  1.000 15.715 0 167 GLY A N   1 ? 
ATOM   948  C CA  . GLY A 1 132 ? -17.288 -13.746 21.292  1.000 15.509 0 167 GLY A CA  1 ? 
ATOM   949  C C   . GLY A 1 132 ? -17.051 -12.336 21.813  1.000 15.872 0 167 GLY A C   1 ? 
ATOM   950  O O   . GLY A 1 132 ? -17.891 -11.800 22.541  1.000 18.756 0 167 GLY A O   1 ? 
ATOM   951  N N   . GLY A 1 133 ? -15.901 -11.733 21.464  1.000 15.672 0 168 GLY A N   1 ? 
ATOM   952  C CA  . GLY A 1 133 ? -15.604 -10.351 21.809  1.000 15.430 0 168 GLY A CA  1 ? 
ATOM   953  C C   . GLY A 1 133 ? -16.439 -9.374  20.991  1.000 16.201 0 168 GLY A C   1 ? 
ATOM   954  O O   . GLY A 1 133 ? -16.899 -8.344  21.496  1.000 15.546 0 168 GLY A O   1 ? 
ATOM   955  N N   . GLY A 1 134 ? -16.635 -9.692  19.709  1.000 16.022 0 169 GLY A N   1 ? 
ATOM   956  C CA  . GLY A 1 134 ? -17.581 -8.932  18.908  1.000 16.829 0 169 GLY A CA  1 ? 
ATOM   957  C C   . GLY A 1 134 ? -18.981 -8.978  19.529  1.000 17.167 0 169 GLY A C   1 ? 
ATOM   958  O O   . GLY A 1 134 ? -19.640 -7.948  19.649  1.000 17.579 0 169 GLY A O   1 ? 
ATOM   959  N N   . GLY A 1 135 ? -19.388 -10.176 19.965  1.000 18.029 0 170 GLY A N   1 ? 
ATOM   960  C CA  . GLY A 1 135 ? -20.662 -10.396 20.632  1.000 18.881 0 170 GLY A CA  1 ? 
ATOM   961  C C   . GLY A 1 135 ? -20.821 -9.561  21.903  1.000 19.315 0 170 GLY A C   1 ? 
ATOM   962  O O   . GLY A 1 135 ? -21.907 -9.082  22.196  1.000 17.476 0 170 GLY A O   1 ? 
ATOM   963  N N   . THR A 1 136 ? -19.726 -9.438  22.656  1.000 18.119 0 171 THR A N   1 ? 
ATOM   964  C CA  . THR A 1 136 ? -19.659 -8.646  23.871  1.000 20.007 0 171 THR A CA  1 ? 
ATOM   965  C C   . THR A 1 136 ? -19.963 -7.173  23.585  1.000 18.944 0 171 THR A C   1 ? 
ATOM   966  O O   . THR A 1 136 ? -20.693 -6.532  24.341  1.000 17.708 0 171 THR A O   1 ? 
ATOM   967  C CB  . THR A 1 136 ? -18.294 -8.859  24.547  1.000 20.772 0 171 THR A CB  1 ? 
ATOM   968  O OG1 . THR A 1 136 ? -18.206 -10.216 24.977  1.000 19.597 0 171 THR A OG1 1 ? 
ATOM   969  C CG2 . THR A 1 136 ? -18.102 -7.991  25.760  1.000 22.992 0 171 THR A CG2 1 ? 
ATOM   970  N N   . LEU A 1 137 ? -19.374 -6.631  22.511  1.000 17.714 0 172 LEU A N   1 ? 
ATOM   971  C CA  . LEU A 1 137 ? -19.595 -5.242  22.150  1.000 18.246 0 172 LEU A CA  1 ? 
ATOM   972  C C   . LEU A 1 137 ? -21.038 -5.028  21.706  1.000 17.610 0 172 LEU A C   1 ? 
ATOM   973  O O   . LEU A 1 137 ? -21.649 -4.030  22.075  1.000 18.008 0 172 LEU A O   1 ? 
ATOM   974  C CB  . LEU A 1 137 ? -18.599 -4.825  21.061  1.000 19.492 0 172 LEU A CB  1 ? 
ATOM   975  C CG  . LEU A 1 137 ? -17.160 -4.679  21.575  1.000 19.559 0 172 LEU A CG  1 ? 
ATOM   976  C CD1 . LEU A 1 137 ? -16.159 -4.802  20.438  1.000 20.436 0 172 LEU A CD1 1 ? 
ATOM   977  C CD2 . LEU A 1 137 ? -16.995 -3.358  22.307  1.000 18.855 0 172 LEU A CD2 1 ? 
ATOM   978  N N   . ILE A 1 138 ? -21.572 -5.963  20.918  1.000 17.388 0 173 ILE A N   1 ? 
ATOM   979  C CA  . ILE A 1 138 ? -22.954 -5.868  20.470  1.000 17.929 0 173 ILE A CA  1 ? 
ATOM   980  C C   . ILE A 1 138 ? -23.884 -5.902  21.686  1.000 17.796 0 173 ILE A C   1 ? 
ATOM   981  O O   . ILE A 1 138 ? -24.793 -5.106  21.768  1.000 19.047 0 173 ILE A O   1 ? 
ATOM   982  C CB  . ILE A 1 138 ? -23.289 -6.969  19.447  1.000 18.321 0 173 ILE A CB  1 ? 
ATOM   983  C CG1 . ILE A 1 138 ? -22.480 -6.814  18.163  1.000 18.984 0 173 ILE A CG1 1 ? 
ATOM   984  C CG2 . ILE A 1 138 ? -24.794 -7.007  19.174  1.000 19.357 0 173 ILE A CG2 1 ? 
ATOM   985  C CD1 . ILE A 1 138 ? -22.557 -8.023  17.242  1.000 19.912 0 173 ILE A CD1 1 ? 
ATOM   986  N N   . LEU A 1 139 ? -23.631 -6.793  22.650  1.000 18.287 0 174 LEU A N   1 ? 
ATOM   987  C CA  . LEU A 1 139 ? -24.491 -6.908  23.808  1.000 19.722 0 174 LEU A CA  1 ? 
ATOM   988  C C   . LEU A 1 139 ? -24.383 -5.673  24.702  1.000 19.954 0 174 LEU A C   1 ? 
ATOM   989  O O   . LEU A 1 139 ? -25.400 -5.194  25.209  1.000 20.007 0 174 LEU A O   1 ? 
ATOM   990  C CB  . LEU A 1 139 ? -24.179 -8.192  24.592  1.000 20.945 0 174 LEU A CB  1 ? 
ATOM   991  C CG  . LEU A 1 139 ? -25.177 -8.488  25.703  1.000 21.336 0 174 LEU A CG  1 ? 
ATOM   992  C CD1 . LEU A 1 139 ? -26.588 -8.684  25.156  1.000 21.042 0 174 LEU A CD1 1 ? 
ATOM   993  C CD2 . LEU A 1 139 ? -24.728 -9.681  26.525  1.000 23.592 0 174 LEU A CD2 1 ? 
ATOM   994  N N   . ALA A 1 140 ? -23.176 -5.129  24.890  1.000 19.588 0 175 ALA A N   1 ? 
ATOM   995  C CA  . ALA A 1 140 ? -23.032 -3.907  25.667  1.000 18.838 0 175 ALA A CA  1 ? 
ATOM   996  C C   . ALA A 1 140 ? -23.908 -2.785  25.097  1.000 19.951 0 175 ALA A C   1 ? 
ATOM   997  O O   . ALA A 1 140 ? -24.463 -1.978  25.848  1.000 20.674 0 175 ALA A O   1 ? 
ATOM   998  C CB  . ALA A 1 140 ? -21.572 -3.518  25.723  1.000 19.536 0 175 ALA A CB  1 ? 
ATOM   999  N N   . GLU A 1 141 ? -24.035 -2.744  23.764  1.000 19.942 0 176 GLU A N   1 ? 
ATOM   1000 C CA  . GLU A 1 141 ? -24.846 -1.746  23.089  1.000 21.639 0 176 GLU A CA  1 ? 
ATOM   1001 C C   . GLU A 1 141 ? -26.338 -2.039  23.317  1.000 23.859 0 176 GLU A C   1 ? 
ATOM   1002 O O   . GLU A 1 141 ? -27.127 -1.110  23.488  1.000 21.875 0 176 GLU A O   1 ? 
ATOM   1003 C CB  . GLU A 1 141 ? -24.497 -1.719  21.594  1.000 23.426 0 176 GLU A CB  1 ? 
ATOM   1004 C CG  . GLU A 1 141 ? -25.293 -0.720  20.786  1.000 25.755 0 176 GLU A CG  1 ? 
ATOM   1005 C CD  . GLU A 1 141 ? -24.835 -0.640  19.338  1.000 28.630 0 176 GLU A CD  1 ? 
ATOM   1006 O OE1 . GLU A 1 141 ? -24.991 -1.650  18.616  1.000 32.022 0 176 GLU A OE1 1 ? 
ATOM   1007 O OE2 . GLU A 1 141 ? -24.284 0.417   18.934  1.000 26.219 0 176 GLU A OE2 1 ? 
ATOM   1008 N N   . ARG A 1 142 ? -26.736 -3.321  23.324  1.000 21.995 0 177 ARG A N   1 ? 
ATOM   1009 C CA  . ARG A 1 142 ? -28.126 -3.689  23.554  1.000 21.689 0 177 ARG A CA  1 ? 
ATOM   1010 C C   . ARG A 1 142 ? -28.546 -3.560  25.016  1.000 21.469 0 177 ARG A C   1 ? 
ATOM   1011 O O   . ARG A 1 142 ? -29.707 -3.272  25.263  1.000 23.060 0 177 ARG A O   1 ? 
ATOM   1012 C CB  . ARG A 1 142 ? -28.411 -5.145  23.212  1.000 22.323 0 177 ARG A CB  1 ? 
ATOM   1013 C CG  . ARG A 1 142 ? -28.209 -5.539  21.763  1.000 24.410 0 177 ARG A CG  1 ? 
ATOM   1014 C CD  . ARG A 1 142 ? -28.690 -6.979  21.626  1.000 26.934 0 177 ARG A CD  1 ? 
ATOM   1015 N NE  . ARG A 1 142 ? -28.246 -7.547  20.366  1.000 28.610 0 177 ARG A NE  1 ? 
ATOM   1016 C CZ  . ARG A 1 142 ? -28.291 -8.830  20.071  1.000 30.303 0 177 ARG A CZ  1 ? 
ATOM   1017 N NH1 . ARG A 1 142 ? -28.702 -9.700  20.984  1.000 29.623 0 177 ARG A NH1 1 ? 
ATOM   1018 N NH2 . ARG A 1 142 ? -27.936 -9.220  18.860  1.000 32.511 0 177 ARG A NH2 1 ? 
ATOM   1019 N N   . ASP A 1 143 ? -27.666 -3.846  25.982  1.000 21.132 0 178 ASP A N   1 ? 
ATOM   1020 C CA  . ASP A 1 143 ? -28.106 -4.069  27.358  1.000 22.280 0 178 ASP A CA  1 ? 
ATOM   1021 C C   . ASP A 1 143 ? -27.405 -3.102  28.311  1.000 23.834 0 178 ASP A C   1 ? 
ATOM   1022 O O   . ASP A 1 143 ? -26.346 -3.416  28.867  1.000 24.427 0 178 ASP A O   1 ? 
ATOM   1023 C CB  . ASP A 1 143 ? -27.931 -5.534  27.787  1.000 23.141 0 178 ASP A CB  1 ? 
ATOM   1024 C CG  . ASP A 1 143 ? -28.370 -5.847  29.214  1.000 24.679 0 178 ASP A CG  1 ? 
ATOM   1025 O OD1 . ASP A 1 143 ? -28.785 -4.907  29.942  1.000 24.277 0 178 ASP A OD1 1 ? 
ATOM   1026 O OD2 . ASP A 1 143 ? -28.268 -7.029  29.611  1.000 25.594 0 178 ASP A OD2 1 ? 
ATOM   1027 N N   . PRO A 1 144 ? -28.031 -1.933  28.587  1.000 23.658 0 179 PRO A N   1 ? 
ATOM   1028 C CA  . PRO A 1 144 ? -27.437 -0.925  29.457  1.000 22.110 0 179 PRO A CA  1 ? 
ATOM   1029 C C   . PRO A 1 144 ? -27.397 -1.255  30.950  1.000 20.331 0 179 PRO A C   1 ? 
ATOM   1030 O O   . PRO A 1 144 ? -26.831 -0.484  31.707  1.000 19.440 0 179 PRO A O   1 ? 
ATOM   1031 C CB  . PRO A 1 144 ? -28.360 0.290   29.226  1.000 24.979 0 179 PRO A CB  1 ? 
ATOM   1032 C CG  . PRO A 1 144 ? -29.725 -0.349  28.987  1.000 26.182 0 179 PRO A CG  1 ? 
ATOM   1033 C CD  . PRO A 1 144 ? -29.388 -1.561  28.129  1.000 25.159 0 179 PRO A CD  1 ? 
ATOM   1034 N N   . SER A 1 145 ? -27.970 -2.384  31.370  1.000 18.358 0 180 SER A N   1 ? 
ATOM   1035 C CA  . SER A 1 145 ? -27.905 -2.788  32.767  1.000 20.063 0 180 SER A CA  1 ? 
ATOM   1036 C C   . SER A 1 145 ? -26.535 -3.370  33.103  1.000 18.839 0 180 SER A C   1 ? 
ATOM   1037 O O   . SER A 1 145 ? -26.190 -3.482  34.269  1.000 18.395 0 180 SER A O   1 ? 
ATOM   1038 C CB  . SER A 1 145 ? -29.002 -3.788  33.122  1.000 20.539 0 180 SER A CB  1 ? 
ATOM   1039 O OG  . SER A 1 145 ? -28.773 -5.065  32.525  1.000 21.831 0 180 SER A OG  1 ? 
ATOM   1040 N N   . LEU A 1 146 ? -25.792 -3.805  32.086  1.000 18.595 0 181 LEU A N   1 ? 
ATOM   1041 C CA  . LEU A 1 146 ? -24.478 -4.396  32.304  1.000 17.738 0 181 LEU A CA  1 ? 
ATOM   1042 C C   . LEU A 1 146 ? -23.565 -3.361  32.943  1.000 18.124 0 181 LEU A C   1 ? 
ATOM   1043 O O   . LEU A 1 146 ? -23.620 -2.177  32.592  1.000 17.941 0 181 LEU A O   1 ? 
ATOM   1044 C CB  . LEU A 1 146 ? -23.923 -4.841  30.949  1.000 16.756 0 181 LEU A CB  1 ? 
ATOM   1045 C CG  . LEU A 1 146 ? -24.567 -6.097  30.379  1.000 16.988 0 181 LEU A CG  1 ? 
ATOM   1046 C CD1 . LEU A 1 146 ? -24.050 -6.379  28.971  1.000 17.415 0 181 LEU A CD1 1 ? 
ATOM   1047 C CD2 . LEU A 1 146 ? -24.315 -7.276  31.310  1.000 16.876 0 181 LEU A CD2 1 ? 
ATOM   1048 N N   . LYS A 1 147 ? -22.659 -3.812  33.810  1.000 18.333 0 182 LYS A N   1 ? 
ATOM   1049 C CA  . LYS A 1 147 ? -21.787 -2.874  34.505  1.000 18.727 0 182 LYS A CA  1 ? 
ATOM   1050 C C   . LYS A 1 147 ? -20.354 -2.922  33.989  1.000 17.384 0 182 LYS A C   1 ? 
ATOM   1051 O O   . LYS A 1 147 ? -19.539 -2.086  34.387  1.000 16.094 0 182 LYS A O   1 ? 
ATOM   1052 C CB  . LYS A 1 147 ? -21.888 -3.121  36.013  1.000 21.170 0 182 LYS A CB  1 ? 
ATOM   1053 C CG  . LYS A 1 147 ? -23.082 -2.463  36.691  1.000 23.844 0 182 LYS A CG  1 ? 
ATOM   1054 C CD  . LYS A 1 147 ? -22.966 -2.617  38.206  1.000 28.813 0 182 LYS A CD  1 ? 
ATOM   1055 C CE  . LYS A 1 147 ? -23.988 -1.828  38.996  1.000 34.181 0 182 LYS A CE  1 ? 
ATOM   1056 N NZ  . LYS A 1 147 ? -25.347 -2.107  38.476  1.000 39.325 0 182 LYS A NZ  1 ? 
ATOM   1057 N N   . ALA A 1 148 ? -20.028 -3.896  33.127  1.000 15.788 0 183 ALA A N   1 ? 
ATOM   1058 C CA  . ALA A 1 148 ? -18.690 -3.997  32.554  1.000 15.663 0 183 ALA A CA  1 ? 
ATOM   1059 C C   . ALA A 1 148 ? -18.694 -4.992  31.405  1.000 15.568 0 183 ALA A C   1 ? 
ATOM   1060 O O   . ALA A 1 148 ? -19.459 -5.953  31.440  1.000 16.388 0 183 ALA A O   1 ? 
ATOM   1061 C CB  . ALA A 1 148 ? -17.679 -4.405  33.598  1.000 15.421 0 183 ALA A CB  1 ? 
ATOM   1062 N N   . ALA A 1 149 ? -17.819 -4.738  30.422  1.000 15.157 0 184 ALA A N   1 ? 
ATOM   1063 C CA  . ALA A 1 149 ? -17.647 -5.580  29.244  1.000 15.208 0 184 ALA A CA  1 ? 
ATOM   1064 C C   . ALA A 1 149 ? -16.159 -5.695  28.896  1.000 16.406 0 184 ALA A C   1 ? 
ATOM   1065 O O   . ALA A 1 149 ? -15.453 -4.687  28.820  1.000 15.168 0 184 ALA A O   1 ? 
ATOM   1066 C CB  . ALA A 1 149 ? -18.429 -5.007  28.084  1.000 15.137 0 184 ALA A CB  1 ? 
ATOM   1067 N N   . VAL A 1 150 ? -15.689 -6.936  28.687  1.000 15.848 0 185 VAL A N   1 ? 
ATOM   1068 C CA  . VAL A 1 150 ? -14.292 -7.184  28.347  1.000 16.210 0 185 VAL A CA  1 ? 
ATOM   1069 C C   . VAL A 1 150 ? -14.225 -8.007  27.062  1.000 15.388 0 185 VAL A C   1 ? 
ATOM   1070 O O   . VAL A 1 150 ? -14.278 -9.238  27.102  1.000 14.620 0 185 VAL A O   1 ? 
ATOM   1071 C CB  . VAL A 1 150 ? -13.519 -7.868  29.489  1.000 16.568 0 185 VAL A CB  1 ? 
ATOM   1072 C CG1 . VAL A 1 150 ? -12.061 -8.085  29.099  1.000 16.616 0 185 VAL A CG1 1 ? 
ATOM   1073 C CG2 . VAL A 1 150 ? -13.575 -7.066  30.785  1.000 15.132 0 185 VAL A CG2 1 ? 
ATOM   1074 N N   . PRO A 1 151 ? -14.156 -7.350  25.878  1.000 13.925 0 186 PRO A N   1 ? 
ATOM   1075 C CA  . PRO A 1 151 ? -13.830 -8.034  24.639  1.000 14.402 0 186 PRO A CA  1 ? 
ATOM   1076 C C   . PRO A 1 151 ? -12.346 -8.368  24.527  1.000 14.764 0 186 PRO A C   1 ? 
ATOM   1077 O O   . PRO A 1 151 ? -11.509 -7.472  24.556  1.000 15.767 0 186 PRO A O   1 ? 
ATOM   1078 C CB  . PRO A 1 151 ? -14.225 -7.050  23.532  1.000 14.357 0 186 PRO A CB  1 ? 
ATOM   1079 C CG  . PRO A 1 151 ? -15.028 -5.965  24.226  1.000 15.253 0 186 PRO A CG  1 ? 
ATOM   1080 C CD  . PRO A 1 151 ? -14.514 -5.957  25.647  1.000 14.753 0 186 PRO A CD  1 ? 
ATOM   1081 N N   . LEU A 1 152 ? -12.064 -9.666  24.391  1.000 15.337 0 187 LEU A N   1 ? 
ATOM   1082 C CA  . LEU A 1 152 ? -10.723 -10.208 24.217  1.000 15.911 0 187 LEU A CA  1 ? 
ATOM   1083 C C   . LEU A 1 152 ? -10.516 -10.516 22.730  1.000 15.330 0 187 LEU A C   1 ? 
ATOM   1084 O O   . LEU A 1 152 ? -11.306 -11.250 22.123  1.000 13.500 0 187 LEU A O   1 ? 
ATOM   1085 C CB  . LEU A 1 152 ? -10.617 -11.476 25.069  1.000 17.509 0 187 LEU A CB  1 ? 
ATOM   1086 C CG  . LEU A 1 152 ? -10.818 -11.325 26.582  1.000 18.171 0 187 LEU A CG  1 ? 
ATOM   1087 C CD1 . LEU A 1 152 ? -10.818 -12.682 27.272  1.000 20.037 0 187 LEU A CD1 1 ? 
ATOM   1088 C CD2 . LEU A 1 152 ? -9.741  -10.435 27.194  1.000 19.160 0 187 LEU A CD2 1 ? 
ATOM   1089 N N   . THR A 1 153 ? -9.430  -9.961  22.174  1.000 14.711 0 188 THR A N   1 ? 
ATOM   1090 C CA  . THR A 1 153 ? -9.088  -10.031 20.757  1.000 16.491 0 188 THR A CA  1 ? 
ATOM   1091 C C   . THR A 1 153 ? -10.361 -10.022 19.917  1.000 16.487 0 188 THR A C   1 ? 
ATOM   1092 O O   . THR A 1 153 ? -10.595 -10.925 19.123  1.000 16.487 0 188 THR A O   1 ? 
ATOM   1093 C CB  . THR A 1 153 ? -8.140  -11.195 20.439  1.000 17.177 0 188 THR A CB  1 ? 
ATOM   1094 O OG1 . THR A 1 153 ? -8.797  -12.437 20.663  1.000 16.264 0 188 THR A OG1 1 ? 
ATOM   1095 C CG2 . THR A 1 153 ? -6.876  -11.141 21.265  1.000 16.461 0 188 THR A CG2 1 ? 
ATOM   1096 N N   . PRO A 1 154 ? -11.194 -8.969  20.071  1.000 17.254 0 189 PRO A N   1 ? 
ATOM   1097 C CA  . PRO A 1 154 ? -12.513 -8.932  19.447  1.000 17.277 0 189 PRO A CA  1 ? 
ATOM   1098 C C   . PRO A 1 154 ? -12.414 -8.833  17.923  1.000 16.799 0 189 PRO A C   1 ? 
ATOM   1099 O O   . PRO A 1 154 ? -11.512 -8.182  17.383  1.000 15.389 0 189 PRO A O   1 ? 
ATOM   1100 C CB  . PRO A 1 154 ? -13.143 -7.654  20.016  1.000 17.043 0 189 PRO A CB  1 ? 
ATOM   1101 C CG  . PRO A 1 154 ? -11.964 -6.762  20.331  1.000 17.421 0 189 PRO A CG  1 ? 
ATOM   1102 C CD  . PRO A 1 154 ? -10.883 -7.723  20.804  1.000 17.125 0 189 PRO A CD  1 ? 
ATOM   1103 N N   . TRP A 1 155 ? -13.347 -9.524  17.266  1.000 18.168 0 190 TRP A N   1 ? 
ATOM   1104 C CA  . TRP A 1 155 ? -13.415 -9.650  15.819  1.000 20.223 0 190 TRP A CA  1 ? 
ATOM   1105 C C   . TRP A 1 155 ? -14.845 -9.334  15.393  1.000 20.056 0 190 TRP A C   1 ? 
ATOM   1106 O O   . TRP A 1 155 ? -15.767 -10.016 15.837  1.000 20.428 0 190 TRP A O   1 ? 
ATOM   1107 C CB  . TRP A 1 155 ? -12.977 -11.068 15.454  1.000 21.984 0 190 TRP A CB  1 ? 
ATOM   1108 C CG  . TRP A 1 155 ? -13.002 -11.435 14.007  1.000 26.623 0 190 TRP A CG  1 ? 
ATOM   1109 C CD1 . TRP A 1 155 ? -12.614 -10.667 12.944  1.000 28.109 0 190 TRP A CD1 1 ? 
ATOM   1110 C CD2 . TRP A 1 155 ? -13.352 -12.732 13.473  1.000 29.815 0 190 TRP A CD2 1 ? 
ATOM   1111 N NE1 . TRP A 1 155 ? -12.755 -11.370 11.779  1.000 31.670 0 190 TRP A NE1 1 ? 
ATOM   1112 C CE2 . TRP A 1 155 ? -13.164 -12.654 12.069  1.000 31.477 0 190 TRP A CE2 1 ? 
ATOM   1113 C CE3 . TRP A 1 155 ? -13.793 -13.948 14.034  1.000 29.666 0 190 TRP A CE3 1 ? 
ATOM   1114 C CZ2 . TRP A 1 155 ? -13.421 -13.741 11.227  1.000 29.812 0 190 TRP A CZ2 1 ? 
ATOM   1115 C CZ3 . TRP A 1 155 ? -14.031 -15.029 13.202  1.000 29.263 0 190 TRP A CZ3 1 ? 
ATOM   1116 C CH2 . TRP A 1 155 ? -13.864 -14.915 11.817  1.000 30.127 0 190 TRP A CH2 1 ? 
ATOM   1117 N N   . HIS A 1 156 ? -15.026 -8.268  14.602  1.000 20.637 0 191 HIS A N   1 ? 
ATOM   1118 C CA  . HIS A 1 156 ? -16.326 -7.955  14.027  1.000 20.825 0 191 HIS A CA  1 ? 
ATOM   1119 C C   . HIS A 1 156 ? -16.184 -6.967  12.870  1.000 21.054 0 191 HIS A C   1 ? 
ATOM   1120 O O   . HIS A 1 156 ? -15.213 -6.218  12.800  1.000 20.138 0 191 HIS A O   1 ? 
ATOM   1121 C CB  . HIS A 1 156 ? -17.271 -7.411  15.108  1.000 22.082 0 191 HIS A CB  1 ? 
ATOM   1122 C CG  . HIS A 1 156 ? -18.702 -7.314  14.670  1.000 23.705 0 191 HIS A CG  1 ? 
ATOM   1123 N ND1 . HIS A 1 156 ? -19.324 -8.274  13.901  1.000 25.611 0 191 HIS A ND1 1 ? 
ATOM   1124 C CD2 . HIS A 1 156 ? -19.627 -6.376  14.886  1.000 25.230 0 191 HIS A CD2 1 ? 
ATOM   1125 C CE1 . HIS A 1 156 ? -20.562 -7.900  13.637  1.000 24.194 0 191 HIS A CE1 1 ? 
ATOM   1126 N NE2 . HIS A 1 156 ? -20.771 -6.776  14.256  1.000 23.939 0 191 HIS A NE2 1 ? 
ATOM   1127 N N   . THR A 1 157 ? -17.177 -6.946  11.969  1.000 21.933 0 192 THR A N   1 ? 
ATOM   1128 C CA  . THR A 1 157 ? -17.095 -6.082  10.798  1.000 22.549 0 192 THR A CA  1 ? 
ATOM   1129 C C   . THR A 1 157 ? -17.681 -4.691  11.082  1.000 21.888 0 192 THR A C   1 ? 
ATOM   1130 O O   . THR A 1 157 ? -17.287 -3.742  10.412  1.000 22.645 0 192 THR A O   1 ? 
ATOM   1131 C CB  . THR A 1 157 ? -17.715 -6.753  9.567   1.000 23.199 0 192 THR A CB  1 ? 
ATOM   1132 O OG1 . THR A 1 157 ? -19.014 -7.179  9.928   1.000 22.293 0 192 THR A OG1 1 ? 
ATOM   1133 C CG2 . THR A 1 157 ? -16.933 -7.951  9.084   1.000 25.665 0 192 THR A CG2 1 ? 
ATOM   1134 N N   . ASP A 1 158 ? -18.593 -4.545  12.058  1.000 21.961 0 193 ASP A N   1 ? 
ATOM   1135 C CA  . ASP A 1 158 ? -19.076 -3.212  12.416  1.000 25.198 0 193 ASP A CA  1 ? 
ATOM   1136 C C   . ASP A 1 158 ? -18.164 -2.663  13.515  1.000 21.658 0 193 ASP A C   1 ? 
ATOM   1137 O O   . ASP A 1 158 ? -17.796 -3.414  14.405  1.000 22.151 0 193 ASP A O   1 ? 
ATOM   1138 C CB  . ASP A 1 158 ? -20.549 -3.170  12.850  1.000 26.079 0 193 ASP A CB  1 ? 
ATOM   1139 C CG  . ASP A 1 158 ? -21.581 -3.677  11.845  1.000 30.669 0 193 ASP A CG  1 ? 
ATOM   1140 O OD1 . ASP A 1 158 ? -21.513 -3.296  10.669  1.000 28.563 0 193 ASP A OD1 1 ? 
ATOM   1141 O OD2 . ASP A 1 158 ? -22.490 -4.446  12.269  1.000 37.979 0 193 ASP A OD2 1 ? 
ATOM   1142 N N   . LYS A 1 159 ? -17.866 -1.357  13.487  1.000 22.740 0 194 LYS A N   1 ? 
ATOM   1143 C CA  . LYS A 1 159 ? -16.836 -0.783  14.352  1.000 24.148 0 194 LYS A CA  1 ? 
ATOM   1144 C C   . LYS A 1 159 ? -17.410 0.130   15.438  1.000 22.675 0 194 LYS A C   1 ? 
ATOM   1145 O O   . LYS A 1 159 ? -16.723 0.400   16.411  1.000 22.530 0 194 LYS A O   1 ? 
ATOM   1146 C CB  . LYS A 1 159 ? -15.798 -0.022  13.514  1.000 26.507 0 194 LYS A CB  1 ? 
ATOM   1147 C CG  . LYS A 1 159 ? -15.247 -0.743  12.279  1.000 27.890 0 194 LYS A CG  1 ? 
ATOM   1148 C CD  . LYS A 1 159 ? -14.589 -2.083  12.552  1.000 30.051 0 194 LYS A CD  1 ? 
ATOM   1149 C CE  . LYS A 1 159 ? -14.119 -2.807  11.292  1.000 31.559 0 194 LYS A CE  1 ? 
ATOM   1150 N NZ  . LYS A 1 159 ? -13.717 -4.226  11.541  1.000 26.654 0 194 LYS A NZ  1 ? 
ATOM   1151 N N   . LYS A 1 160 ? -18.673 0.566   15.314  1.000 24.281 0 195 LYS A N   1 ? 
ATOM   1152 C CA  . LYS A 1 160 ? -19.254 1.570   16.198  1.000 24.467 0 195 LYS A CA  1 ? 
ATOM   1153 C C   . LYS A 1 160 ? -20.256 0.943   17.162  1.000 21.963 0 195 LYS A C   1 ? 
ATOM   1154 O O   . LYS A 1 160 ? -21.255 0.372   16.746  1.000 21.616 0 195 LYS A O   1 ? 
ATOM   1155 C CB  . LYS A 1 160 ? -19.932 2.672   15.376  1.000 27.776 0 195 LYS A CB  1 ? 
ATOM   1156 C CG  . LYS A 1 160 ? -18.952 3.504   14.578  1.000 33.453 0 195 LYS A CG  1 ? 
ATOM   1157 C CD  . LYS A 1 160 ? -19.530 4.370   13.483  1.000 41.099 0 195 LYS A CD  1 ? 
ATOM   1158 C CE  . LYS A 1 160 ? -18.455 4.770   12.490  1.000 43.049 0 195 LYS A CE  1 ? 
ATOM   1159 N NZ  . LYS A 1 160 ? -18.788 6.062   11.855  1.000 51.442 0 195 LYS A NZ  1 ? 
ATOM   1160 N N   . PHE A 1 161 ? -20.008 1.108   18.461  1.000 20.792 0 196 PHE A N   1 ? 
ATOM   1161 C CA  . PHE A 1 161 ? -20.901 0.593   19.481  1.000 20.809 0 196 PHE A CA  1 ? 
ATOM   1162 C C   . PHE A 1 161 ? -21.265 1.740   20.414  1.000 22.084 0 196 PHE A C   1 ? 
ATOM   1163 O O   . PHE A 1 161 ? -20.398 2.359   21.022  1.000 22.428 0 196 PHE A O   1 ? 
ATOM   1164 C CB  . PHE A 1 161 ? -20.292 -0.613  20.195  1.000 20.022 0 196 PHE A CB  1 ? 
ATOM   1165 C CG  . PHE A 1 161 ? -19.881 -1.697  19.241  1.000 20.484 0 196 PHE A CG  1 ? 
ATOM   1166 C CD1 . PHE A 1 161 ? -20.813 -2.610  18.764  1.000 20.446 0 196 PHE A CD1 1 ? 
ATOM   1167 C CD2 . PHE A 1 161 ? -18.586 -1.742  18.746  1.000 19.678 0 196 PHE A CD2 1 ? 
ATOM   1168 C CE1 . PHE A 1 161 ? -20.442 -3.582  17.847  1.000 19.369 0 196 PHE A CE1 1 ? 
ATOM   1169 C CE2 . PHE A 1 161 ? -18.223 -2.709  17.826  1.000 19.256 0 196 PHE A CE2 1 ? 
ATOM   1170 C CZ  . PHE A 1 161 ? -19.145 -3.631  17.392  1.000 19.149 0 196 PHE A CZ  1 ? 
ATOM   1171 N N   . ASN A 1 162 ? -22.573 2.019   20.452  1.000 21.225 0 197 ASN A N   1 ? 
ATOM   1172 C CA  . ASN A 1 162 ? -23.150 3.070   21.256  1.000 21.898 0 197 ASN A CA  1 ? 
ATOM   1173 C C   . ASN A 1 162 ? -23.501 2.454   22.606  1.000 22.430 0 197 ASN A C   1 ? 
ATOM   1174 O O   . ASN A 1 162 ? -24.622 1.953   22.776  1.000 20.830 0 197 ASN A O   1 ? 
ATOM   1175 C CB  . ASN A 1 162 ? -24.385 3.662   20.563  1.000 22.150 0 197 ASN A CB  1 ? 
ATOM   1176 C CG  . ASN A 1 162 ? -24.994 4.794   21.365  1.000 26.035 0 197 ASN A CG  1 ? 
ATOM   1177 O OD1 . ASN A 1 162 ? -24.300 5.396   22.181  1.000 25.047 0 197 ASN A OD1 1 ? 
ATOM   1178 N ND2 . ASN A 1 162 ? -26.272 5.087   21.156  1.000 28.914 0 197 ASN A ND2 1 ? 
ATOM   1179 N N   . THR A 1 163 ? -22.543 2.478   23.540  1.000 20.610 0 198 THR A N   1 ? 
ATOM   1180 C CA  . THR A 1 163 ? -22.760 1.924   24.871  1.000 20.432 0 198 THR A CA  1 ? 
ATOM   1181 C C   . THR A 1 163 ? -22.150 2.837   25.938  1.000 20.314 0 198 THR A C   1 ? 
ATOM   1182 O O   . THR A 1 163 ? -21.078 3.409   25.733  1.000 19.674 0 198 THR A O   1 ? 
ATOM   1183 C CB  . THR A 1 163 ? -22.195 0.498   24.992  1.000 19.841 0 198 THR A CB  1 ? 
ATOM   1184 O OG1 . THR A 1 163 ? -22.604 -0.003  26.263  1.000 21.204 0 198 THR A OG1 1 ? 
ATOM   1185 C CG2 . THR A 1 163 ? -20.684 0.422   24.887  1.000 20.382 0 198 THR A CG2 1 ? 
ATOM   1186 N N   . LYS A 1 164 ? -22.799 2.861   27.116  1.000 19.953 0 199 LYS A N   1 ? 
ATOM   1187 C CA  . LYS A 1 164 ? -22.251 3.480   28.311  1.000 21.789 0 199 LYS A CA  1 ? 
ATOM   1188 C C   . LYS A 1 164 ? -21.520 2.488   29.204  1.000 18.693 0 199 LYS A C   1 ? 
ATOM   1189 O O   . LYS A 1 164 ? -20.941 2.892   30.208  1.000 17.124 0 199 LYS A O   1 ? 
ATOM   1190 C CB  . LYS A 1 164 ? -23.365 4.047   29.185  1.000 26.103 0 199 LYS A CB  1 ? 
ATOM   1191 C CG  . LYS A 1 164 ? -24.142 5.222   28.613  1.000 31.716 0 199 LYS A CG  1 ? 
ATOM   1192 C CD  . LYS A 1 164 ? -24.902 5.939   29.752  1.000 36.013 0 199 LYS A CD  1 ? 
ATOM   1193 C CE  . LYS A 1 164 ? -26.149 6.663   29.300  1.000 42.429 0 199 LYS A CE  1 ? 
ATOM   1194 N NZ  . LYS A 1 164 ? -25.889 7.484   28.093  1.000 46.027 0 199 LYS A NZ  1 ? 
ATOM   1195 N N   . VAL A 1 165 ? -21.603 1.190   28.874  1.000 18.108 0 200 VAL A N   1 ? 
ATOM   1196 C CA  . VAL A 1 165 ? -21.023 0.129   29.686  1.000 16.025 0 200 VAL A CA  1 ? 
ATOM   1197 C C   . VAL A 1 165 ? -19.501 0.257   29.605  1.000 15.453 0 200 VAL A C   1 ? 
ATOM   1198 O O   . VAL A 1 165 ? -18.948 0.424   28.515  1.000 14.818 0 200 VAL A O   1 ? 
ATOM   1199 C CB  . VAL A 1 165 ? -21.499 -1.263  29.225  1.000 15.872 0 200 VAL A CB  1 ? 
ATOM   1200 C CG1 . VAL A 1 165 ? -20.861 -2.394  30.047  1.000 16.304 0 200 VAL A CG1 1 ? 
ATOM   1201 C CG2 . VAL A 1 165 ? -23.017 -1.354  29.257  1.000 15.596 0 200 VAL A CG2 1 ? 
ATOM   1202 N N   . PRO A 1 166 ? -18.776 0.271   30.742  1.000 14.734 0 201 PRO A N   1 ? 
ATOM   1203 C CA  . PRO A 1 166 ? -17.317 0.323   30.687  1.000 14.403 0 201 PRO A CA  1 ? 
ATOM   1204 C C   . PRO A 1 166 ? -16.727 -0.828  29.874  1.000 14.479 0 201 PRO A C   1 ? 
ATOM   1205 O O   . PRO A 1 166 ? -16.995 -1.996  30.167  1.000 15.383 0 201 PRO A O   1 ? 
ATOM   1206 C CB  . PRO A 1 166 ? -16.921 0.247   32.170  1.000 14.294 0 201 PRO A CB  1 ? 
ATOM   1207 C CG  . PRO A 1 166 ? -18.086 0.863   32.903  1.000 14.686 0 201 PRO A CG  1 ? 
ATOM   1208 C CD  . PRO A 1 166 ? -19.292 0.384   32.122  1.000 15.399 0 201 PRO A CD  1 ? 
ATOM   1209 N N   . VAL A 1 167 ? -15.901 -0.487  28.879  1.000 14.378 0 202 VAL A N   1 ? 
ATOM   1210 C CA  . VAL A 1 167 ? -15.317 -1.457  27.968  1.000 14.821 0 202 VAL A CA  1 ? 
ATOM   1211 C C   . VAL A 1 167 ? -13.798 -1.516  28.138  1.000 14.175 0 202 VAL A C   1 ? 
ATOM   1212 O O   . VAL A 1 167 ? -13.102 -0.520  27.896  1.000 14.395 0 202 VAL A O   1 ? 
ATOM   1213 C CB  . VAL A 1 167 ? -15.675 -1.104  26.513  1.000 15.344 0 202 VAL A CB  1 ? 
ATOM   1214 C CG1 . VAL A 1 167 ? -14.924 -1.989  25.524  1.000 15.658 0 202 VAL A CG1 1 ? 
ATOM   1215 C CG2 . VAL A 1 167 ? -17.179 -1.164  26.257  1.000 16.491 0 202 VAL A CG2 1 ? 
ATOM   1216 N N   . LEU A 1 168 ? -13.293 -2.707  28.473  1.000 13.263 0 203 LEU A N   1 ? 
ATOM   1217 C CA  . LEU A 1 168 ? -11.874 -3.034  28.429  1.000 14.540 0 203 LEU A CA  1 ? 
ATOM   1218 C C   . LEU A 1 168 ? -11.589 -3.956  27.238  1.000 14.992 0 203 LEU A C   1 ? 
ATOM   1219 O O   . LEU A 1 168 ? -11.938 -5.126  27.283  1.000 15.457 0 203 LEU A O   1 ? 
ATOM   1220 C CB  . LEU A 1 168 ? -11.463 -3.718  29.732  1.000 14.952 0 203 LEU A CB  1 ? 
ATOM   1221 C CG  . LEU A 1 168 ? -10.130 -4.472  29.709  1.000 16.127 0 203 LEU A CG  1 ? 
ATOM   1222 C CD1 . LEU A 1 168 ? -8.955  -3.548  29.374  1.000 15.396 0 203 LEU A CD1 1 ? 
ATOM   1223 C CD2 . LEU A 1 168 ? -9.856  -5.195  31.024  1.000 15.903 0 203 LEU A CD2 1 ? 
ATOM   1224 N N   . ILE A 1 169 ? -10.954 -3.403  26.189  1.000 14.217 0 204 ILE A N   1 ? 
ATOM   1225 C CA  . ILE A 1 169 ? -10.600 -4.163  25.008  1.000 15.503 0 204 ILE A CA  1 ? 
ATOM   1226 C C   . ILE A 1 169 ? -9.154  -4.601  25.151  1.000 16.563 0 204 ILE A C   1 ? 
ATOM   1227 O O   . ILE A 1 169 ? -8.264  -3.748  25.370  1.000 17.649 0 204 ILE A O   1 ? 
ATOM   1228 C CB  . ILE A 1 169 ? -10.808 -3.312  23.746  1.000 15.422 0 204 ILE A CB  1 ? 
ATOM   1229 C CG1 . ILE A 1 169 ? -12.294 -3.091  23.456  1.000 16.269 0 204 ILE A CG1 1 ? 
ATOM   1230 C CG2 . ILE A 1 169 ? -10.072 -3.920  22.574  1.000 15.365 0 204 ILE A CG2 1 ? 
ATOM   1231 C CD1 . ILE A 1 169 ? -12.557 -1.856  22.623  1.000 18.872 0 204 ILE A CD1 1 ? 
ATOM   1232 N N   . ILE A 1 170 ? -8.932  -5.918  25.062  1.000 16.390 0 205 ILE A N   1 ? 
ATOM   1233 C CA  . ILE A 1 170 ? -7.577  -6.444  25.066  1.000 16.959 0 205 ILE A CA  1 ? 
ATOM   1234 C C   . ILE A 1 170 ? -7.301  -7.073  23.704  1.000 17.796 0 205 ILE A C   1 ? 
ATOM   1235 O O   . ILE A 1 170 ? -7.936  -8.059  23.312  1.000 17.188 0 205 ILE A O   1 ? 
ATOM   1236 C CB  . ILE A 1 170 ? -7.349  -7.437  26.217  1.000 18.512 0 205 ILE A CB  1 ? 
ATOM   1237 C CG1 . ILE A 1 170 ? -7.553  -6.754  27.570  1.000 17.859 0 205 ILE A CG1 1 ? 
ATOM   1238 C CG2 . ILE A 1 170 ? -5.948  -8.046  26.105  1.000 20.450 0 205 ILE A CG2 1 ? 
ATOM   1239 C CD1 . ILE A 1 170 ? -7.446  -7.674  28.737  1.000 18.423 0 205 ILE A CD1 1 ? 
ATOM   1240 N N   . GLY A 1 171 ? -6.358  -6.458  22.985  1.000 15.995 0 206 GLY A N   1 ? 
ATOM   1241 C CA  . GLY A 1 171 ? -5.966  -6.906  21.664  1.000 15.979 0 206 GLY A CA  1 ? 
ATOM   1242 C C   . GLY A 1 171 ? -4.600  -7.576  21.726  1.000 14.696 0 206 GLY A C   1 ? 
ATOM   1243 O O   . GLY A 1 171 ? -3.923  -7.554  22.755  1.000 13.700 0 206 GLY A O   1 ? 
ATOM   1244 N N   . ALA A 1 172 ? -4.209  -8.134  20.586  1.000 14.593 0 207 ALA A N   1 ? 
ATOM   1245 C CA  . ALA A 1 172 ? -2.938  -8.828  20.409  1.000 14.076 0 207 ALA A CA  1 ? 
ATOM   1246 C C   . ALA A 1 172 ? -2.165  -8.111  19.308  1.000 15.001 0 207 ALA A C   1 ? 
ATOM   1247 O O   . ALA A 1 172 ? -2.713  -7.836  18.239  1.000 15.421 0 207 ALA A O   1 ? 
ATOM   1248 C CB  . ALA A 1 172 ? -3.210  -10.271 20.041  1.000 13.688 0 207 ALA A CB  1 ? 
ATOM   1249 N N   . GLU A 1 173 ? -0.885  -7.841  19.557  1.000 16.663 0 208 GLU A N   1 ? 
ATOM   1250 C CA  . GLU A 1 173 ? -0.084  -7.054  18.639  1.000 18.978 0 208 GLU A CA  1 ? 
ATOM   1251 C C   . GLU A 1 173 ? 0.001   -7.722  17.263  1.000 20.433 0 208 GLU A C   1 ? 
ATOM   1252 O O   . GLU A 1 173 ? -0.046  -7.025  16.242  1.000 20.525 0 208 GLU A O   1 ? 
ATOM   1253 C CB  . GLU A 1 173 ? 1.322   -6.891  19.217  1.000 22.138 0 208 GLU A CB  1 ? 
ATOM   1254 C CG  . GLU A 1 173 ? 2.168   -5.903  18.442  1.000 25.835 0 208 GLU A CG  1 ? 
ATOM   1255 C CD  . GLU A 1 173 ? 3.593   -5.770  18.951  1.000 27.296 0 208 GLU A CD  1 ? 
ATOM   1256 O OE1 . GLU A 1 173 ? 4.053   -6.655  19.690  1.000 25.202 0 208 GLU A OE1 1 ? 
ATOM   1257 O OE2 . GLU A 1 173 ? 4.223   -4.747  18.637  1.000 33.179 0 208 GLU A OE2 1 ? 
ATOM   1258 N N   . ALA A 1 174 ? 0.148   -9.057  17.246  1.000 20.431 0 209 ALA A N   1 ? 
ATOM   1259 C CA  . ALA A 1 174 ? 0.389   -9.798  16.011  1.000 21.975 0 209 ALA A CA  1 ? 
ATOM   1260 C C   . ALA A 1 174 ? -0.853  -10.573 15.582  1.000 21.365 0 209 ALA A C   1 ? 
ATOM   1261 O O   . ALA A 1 174 ? -0.746  -11.670 15.067  1.000 25.702 0 209 ALA A O   1 ? 
ATOM   1262 C CB  . ALA A 1 174 ? 1.570   -10.736 16.196  1.000 20.988 0 209 ALA A CB  1 ? 
ATOM   1263 N N   . ASP A 1 175 ? -2.039  -10.001 15.785  1.000 22.001 0 210 ASP A N   1 ? 
ATOM   1264 C CA  . ASP A 1 175 ? -3.273  -10.709 15.516  1.000 20.427 0 210 ASP A CA  1 ? 
ATOM   1265 C C   . ASP A 1 175 ? -3.478  -10.839 14.002  1.000 20.982 0 210 ASP A C   1 ? 
ATOM   1266 O O   . ASP A 1 175 ? -3.695  -9.866  13.309  1.000 23.716 0 210 ASP A O   1 ? 
ATOM   1267 C CB  . ASP A 1 175 ? -4.436  -10.008 16.221  1.000 20.358 0 210 ASP A CB  1 ? 
ATOM   1268 C CG  . ASP A 1 175 ? -5.688  -10.866 16.317  1.000 20.265 0 210 ASP A CG  1 ? 
ATOM   1269 O OD1 . ASP A 1 175 ? -5.915  -11.658 15.375  1.000 19.677 0 210 ASP A OD1 1 ? 
ATOM   1270 O OD2 . ASP A 1 175 ? -6.448  -10.706 17.295  1.000 20.695 0 210 ASP A OD2 1 ? 
ATOM   1271 N N   . THR A 1 176 ? -3.454  -12.065 13.483  1.000 21.271 0 211 THR A N   1 ? 
ATOM   1272 C CA  . THR A 1 176 ? -3.641  -12.330 12.060  1.000 21.100 0 211 THR A CA  1 ? 
ATOM   1273 C C   . THR A 1 176 ? -5.125  -12.430 11.669  1.000 20.780 0 211 THR A C   1 ? 
ATOM   1274 O O   . THR A 1 176 ? -5.440  -12.459 10.486  1.000 22.215 0 211 THR A O   1 ? 
ATOM   1275 C CB  . THR A 1 176 ? -2.928  -13.641 11.680  1.000 20.463 0 211 THR A CB  1 ? 
ATOM   1276 O OG1 . THR A 1 176 ? -3.433  -14.745 12.446  1.000 21.543 0 211 THR A OG1 1 ? 
ATOM   1277 C CG2 . THR A 1 176 ? -1.436  -13.567 11.911  1.000 20.857 0 211 THR A CG2 1 ? 
ATOM   1278 N N   . VAL A 1 177 ? -6.036  -12.492 12.640  1.000 18.287 0 212 VAL A N   1 ? 
ATOM   1279 C CA  . VAL A 1 177 ? -7.460  -12.692 12.363  1.000 19.440 0 212 VAL A CA  1 ? 
ATOM   1280 C C   . VAL A 1 177 ? -8.203  -11.369 12.533  1.000 17.968 0 212 VAL A C   1 ? 
ATOM   1281 O O   . VAL A 1 177 ? -9.048  -11.011 11.738  1.000 16.283 0 212 VAL A O   1 ? 
ATOM   1282 C CB  . VAL A 1 177 ? -8.060  -13.767 13.298  1.000 19.617 0 212 VAL A CB  1 ? 
ATOM   1283 C CG1 . VAL A 1 177 ? -9.577  -13.852 13.165  1.000 21.498 0 212 VAL A CG1 1 ? 
ATOM   1284 C CG2 . VAL A 1 177 ? -7.402  -15.119 13.091  1.000 21.109 0 212 VAL A CG2 1 ? 
ATOM   1285 N N   . ALA A 1 178 ? -7.918  -10.678 13.638  1.000 19.050 0 213 ALA A N   1 ? 
ATOM   1286 C CA  . ALA A 1 178 ? -8.574  -9.426  13.955  1.000 20.339 0 213 ALA A CA  1 ? 
ATOM   1287 C C   . ALA A 1 178 ? -7.504  -8.381  14.263  1.000 18.007 0 213 ALA A C   1 ? 
ATOM   1288 O O   . ALA A 1 178 ? -7.360  -7.970  15.402  1.000 17.281 0 213 ALA A O   1 ? 
ATOM   1289 C CB  . ALA A 1 178 ? -9.520  -9.642  15.118  1.000 21.984 0 213 ALA A CB  1 ? 
ATOM   1290 N N   . PRO A 1 179 ? -6.720  -7.943  13.257  1.000 18.363 0 214 PRO A N   1 ? 
ATOM   1291 C CA  . PRO A 1 179 ? -5.668  -6.955  13.466  1.000 18.365 0 214 PRO A CA  1 ? 
ATOM   1292 C C   . PRO A 1 179 ? -6.224  -5.740  14.190  1.000 18.266 0 214 PRO A C   1 ? 
ATOM   1293 O O   . PRO A 1 179 ? -7.303  -5.256  13.867  1.000 17.699 0 214 PRO A O   1 ? 
ATOM   1294 C CB  . PRO A 1 179 ? -5.163  -6.605  12.061  1.000 18.802 0 214 PRO A CB  1 ? 
ATOM   1295 C CG  . PRO A 1 179 ? -6.143  -7.234  11.108  1.000 19.198 0 214 PRO A CG  1 ? 
ATOM   1296 C CD  . PRO A 1 179 ? -6.814  -8.364  11.854  1.000 18.371 0 214 PRO A CD  1 ? 
ATOM   1297 N N   . VAL A 1 180 ? -5.499  -5.274  15.201  1.000 18.001 0 215 VAL A N   1 ? 
ATOM   1298 C CA  . VAL A 1 180 ? -6.030  -4.262  16.101  1.000 18.756 0 215 VAL A CA  1 ? 
ATOM   1299 C C   . VAL A 1 180 ? -6.296  -2.964  15.341  1.000 19.684 0 215 VAL A C   1 ? 
ATOM   1300 O O   . VAL A 1 180 ? -7.219  -2.216  15.680  1.000 19.635 0 215 VAL A O   1 ? 
ATOM   1301 C CB  . VAL A 1 180 ? -5.109  -4.027  17.318  1.000 18.872 0 215 VAL A CB  1 ? 
ATOM   1302 C CG1 . VAL A 1 180 ? -5.009  -5.274  18.175  1.000 17.719 0 215 VAL A CG1 1 ? 
ATOM   1303 C CG2 . VAL A 1 180 ? -3.729  -3.513  16.909  1.000 19.075 0 215 VAL A CG2 1 ? 
ATOM   1304 N N   . SER A 1 181 ? -5.507  -2.694  14.294  1.000 19.512 0 216 SER A N   1 ? 
ATOM   1305 C CA  . SER A 1 181 ? -5.730  -1.476  13.528  1.000 20.682 0 216 SER A CA  1 ? 
ATOM   1306 C C   . SER A 1 181 ? -7.096  -1.501  12.834  1.000 21.875 0 216 SER A C   1 ? 
ATOM   1307 O O   . SER A 1 181 ? -7.629  -0.447  12.517  1.000 22.422 0 216 SER A O   1 ? 
ATOM   1308 C CB  . SER A 1 181 ? -4.633  -1.220  12.542  1.000 20.510 0 216 SER A CB  1 ? 
ATOM   1309 O OG  . SER A 1 181 ? -4.715  -2.196  11.523  1.000 20.805 0 216 SER A OG  1 ? 
ATOM   1310 N N   . GLN A 1 182 ? -7.683  -2.682  12.603  1.000 23.617 0 217 GLN A N   1 ? 
ATOM   1311 C CA  . GLN A 1 182 ? -8.975  -2.760  11.930  1.000 23.804 0 217 GLN A CA  1 ? 
ATOM   1312 C C   . GLN A 1 182 ? -10.125 -3.207  12.837  1.000 21.696 0 217 GLN A C   1 ? 
ATOM   1313 O O   . GLN A 1 182 ? -11.291 -3.091  12.443  1.000 21.570 0 217 GLN A O   1 ? 
ATOM   1314 C CB  . GLN A 1 182 ? -8.855  -3.711  10.743  1.000 28.024 0 217 GLN A CB  1 ? 
ATOM   1315 C CG  . GLN A 1 182 ? -7.880  -3.190  9.703   1.000 34.071 0 217 GLN A CG  1 ? 
ATOM   1316 C CD  . GLN A 1 182 ? -7.716  -4.194  8.601   1.000 40.858 0 217 GLN A CD  1 ? 
ATOM   1317 O OE1 . GLN A 1 182 ? -7.215  -5.294  8.811   1.000 49.596 0 217 GLN A OE1 1 ? 
ATOM   1318 N NE2 . GLN A 1 182 ? -8.163  -3.813  7.418   1.000 48.858 0 217 GLN A NE2 1 ? 
ATOM   1319 N N   . HIS A 1 183 ? -9.813  -3.757  14.014  1.000 19.293 0 218 HIS A N   1 ? 
ATOM   1320 C CA  . HIS A 1 183 ? -10.827 -4.248  14.935  1.000 18.827 0 218 HIS A CA  1 ? 
ATOM   1321 C C   . HIS A 1 183 ? -10.717 -3.503  16.265  1.000 18.761 0 218 HIS A C   1 ? 
ATOM   1322 O O   . HIS A 1 183 ? -11.357 -2.456  16.425  1.000 18.814 0 218 HIS A O   1 ? 
ATOM   1323 C CB  . HIS A 1 183 ? -10.754 -5.772  15.046  1.000 19.344 0 218 HIS A CB  1 ? 
ATOM   1324 C CG  . HIS A 1 183 ? -11.054 -6.434  13.749  1.000 18.835 0 218 HIS A CG  1 ? 
ATOM   1325 N ND1 . HIS A 1 183 ? -12.315 -6.866  13.430  1.000 19.822 0 218 HIS A ND1 1 ? 
ATOM   1326 C CD2 . HIS A 1 183 ? -10.292 -6.684  12.673  1.000 18.856 0 218 HIS A CD2 1 ? 
ATOM   1327 C CE1 . HIS A 1 183 ? -12.285 -7.384  12.197  1.000 19.086 0 218 HIS A CE1 1 ? 
ATOM   1328 N NE2 . HIS A 1 183 ? -11.076 -7.268  11.720  1.000 18.624 0 218 HIS A NE2 1 ? 
ATOM   1329 N N   . ALA A 1 184 ? -9.896  -4.022  17.185  1.000 16.705 0 219 ALA A N   1 ? 
ATOM   1330 C CA  . ALA A 1 184 ? -9.820  -3.531  18.555  1.000 17.108 0 219 ALA A CA  1 ? 
ATOM   1331 C C   . ALA A 1 184 ? -9.739  -2.006  18.630  1.000 17.212 0 219 ALA A C   1 ? 
ATOM   1332 O O   . ALA A 1 184 ? -10.414 -1.402  19.453  1.000 15.620 0 219 ALA A O   1 ? 
ATOM   1333 C CB  . ALA A 1 184 ? -8.636  -4.156  19.257  1.000 17.256 0 219 ALA A CB  1 ? 
ATOM   1334 N N   . LEU A 1 185 ? -8.853  -1.382  17.838  1.000 18.680 0 220 LEU A N   1 ? 
ATOM   1335 C CA  . LEU A 1 185 ? -8.649  0.054   17.963  1.000 19.081 0 220 LEU A CA  1 ? 
ATOM   1336 C C   . LEU A 1 185 ? -9.869  0.828   17.458  1.000 19.494 0 220 LEU A C   1 ? 
ATOM   1337 O O   . LEU A 1 185 ? -10.363 1.682   18.195  1.000 20.081 0 220 LEU A O   1 ? 
ATOM   1338 C CB  . LEU A 1 185 ? -7.341  0.508   17.294  1.000 20.040 0 220 LEU A CB  1 ? 
ATOM   1339 C CG  . LEU A 1 185 ? -7.027  2.000   17.422  1.000 19.952 0 220 LEU A CG  1 ? 
ATOM   1340 C CD1 . LEU A 1 185 ? -7.093  2.455   18.868  1.000 20.235 0 220 LEU A CD1 1 ? 
ATOM   1341 C CD2 . LEU A 1 185 ? -5.658  2.310   16.834  1.000 21.684 0 220 LEU A CD2 1 ? 
ATOM   1342 N N   . PRO A 1 186 ? -10.388 0.629   16.216  1.000 19.580 0 221 PRO A N   1 ? 
ATOM   1343 C CA  . PRO A 1 186 ? -11.667 1.234   15.825  1.000 20.037 0 221 PRO A CA  1 ? 
ATOM   1344 C C   . PRO A 1 186 ? -12.784 1.047   16.856  1.000 19.393 0 221 PRO A C   1 ? 
ATOM   1345 O O   . PRO A 1 186 ? -13.555 1.983   17.101  1.000 20.086 0 221 PRO A O   1 ? 
ATOM   1346 C CB  . PRO A 1 186 ? -12.012 0.547   14.485  1.000 20.103 0 221 PRO A CB  1 ? 
ATOM   1347 C CG  . PRO A 1 186 ? -10.675 0.180   13.912  1.000 19.741 0 221 PRO A CG  1 ? 
ATOM   1348 C CD  . PRO A 1 186 ? -9.766  -0.092  15.097  1.000 19.406 0 221 PRO A CD  1 ? 
ATOM   1349 N N   . PHE A 1 187 ? -12.865 -0.141  17.474  1.000 18.395 0 222 PHE A N   1 ? 
ATOM   1350 C CA  . PHE A 1 187 ? -13.898 -0.399  18.467  1.000 17.951 0 222 PHE A CA  1 ? 
ATOM   1351 C C   . PHE A 1 187 ? -13.740 0.577   19.630  1.000 19.116 0 222 PHE A C   1 ? 
ATOM   1352 O O   . PHE A 1 187 ? -14.706 1.215   20.064  1.000 19.129 0 222 PHE A O   1 ? 
ATOM   1353 C CB  . PHE A 1 187 ? -13.854 -1.826  19.007  1.000 17.992 0 222 PHE A CB  1 ? 
ATOM   1354 C CG  . PHE A 1 187 ? -13.997 -2.924  17.991  1.000 19.956 0 222 PHE A CG  1 ? 
ATOM   1355 C CD1 . PHE A 1 187 ? -14.621 -2.692  16.779  1.000 19.279 0 222 PHE A CD1 1 ? 
ATOM   1356 C CD2 . PHE A 1 187 ? -13.487 -4.197  18.242  1.000 18.846 0 222 PHE A CD2 1 ? 
ATOM   1357 C CE1 . PHE A 1 187 ? -14.733 -3.704  15.840  1.000 19.690 0 222 PHE A CE1 1 ? 
ATOM   1358 C CE2 . PHE A 1 187 ? -13.620 -5.205  17.302  1.000 19.038 0 222 PHE A CE2 1 ? 
ATOM   1359 C CZ  . PHE A 1 187 ? -14.254 -4.963  16.109  1.000 19.300 0 222 PHE A CZ  1 ? 
ATOM   1360 N N   . PHE A 1 188 ? -12.504 0.710   20.110  1.000 18.152 0 223 PHE A N   1 ? 
ATOM   1361 C CA  . PHE A 1 188 ? -12.200 1.661   21.163  1.000 18.633 0 223 PHE A CA  1 ? 
ATOM   1362 C C   . PHE A 1 188 ? -12.513 3.095   20.719  1.000 19.249 0 223 PHE A C   1 ? 
ATOM   1363 O O   . PHE A 1 188 ? -13.154 3.836   21.459  1.000 19.299 0 223 PHE A O   1 ? 
ATOM   1364 C CB  . PHE A 1 188 ? -10.724 1.537   21.543  1.000 17.436 0 223 PHE A CB  1 ? 
ATOM   1365 C CG  . PHE A 1 188 ? -10.262 2.525   22.572  1.000 17.164 0 223 PHE A CG  1 ? 
ATOM   1366 C CD1 . PHE A 1 188 ? -10.441 2.262   23.918  1.000 16.987 0 223 PHE A CD1 1 ? 
ATOM   1367 C CD2 . PHE A 1 188 ? -9.637  3.707   22.193  1.000 17.476 0 223 PHE A CD2 1 ? 
ATOM   1368 C CE1 . PHE A 1 188 ? -9.991  3.158   24.877  1.000 16.342 0 223 PHE A CE1 1 ? 
ATOM   1369 C CE2 . PHE A 1 188 ? -9.209  4.610   23.153  1.000 17.732 0 223 PHE A CE2 1 ? 
ATOM   1370 C CZ  . PHE A 1 188 ? -9.412  4.344   24.491  1.000 16.855 0 223 PHE A CZ  1 ? 
ATOM   1371 N N   . GLU A 1 189 ? -12.062 3.478   19.513  1.000 18.955 0 224 GLU A N   1 ? 
ATOM   1372 C CA  . GLU A 1 189 ? -12.098 4.868   19.090  1.000 20.845 0 224 GLU A CA  1 ? 
ATOM   1373 C C   . GLU A 1 189 ? -13.537 5.329   18.893  1.000 20.974 0 224 GLU A C   1 ? 
ATOM   1374 O O   . GLU A 1 189 ? -13.815 6.509   19.022  1.000 19.094 0 224 GLU A O   1 ? 
ATOM   1375 C CB  . GLU A 1 189 ? -11.269 5.087   17.820  1.000 23.222 0 224 GLU A CB  1 ? 
ATOM   1376 C CG  . GLU A 1 189 ? -9.785  5.086   18.112  1.000 25.402 0 224 GLU A CG  1 ? 
ATOM   1377 C CD  . GLU A 1 189 ? -8.863  5.253   16.911  1.000 32.744 0 224 GLU A CD  1 ? 
ATOM   1378 O OE1 . GLU A 1 189 ? -9.307  4.996   15.755  1.000 37.726 0 224 GLU A OE1 1 ? 
ATOM   1379 O OE2 . GLU A 1 189 ? -7.675  5.623   17.134  1.000 37.680 0 224 GLU A OE2 1 ? 
ATOM   1380 N N   . ASN A 1 190 ? -14.460 4.405   18.619  1.000 20.662 0 225 ASN A N   1 ? 
ATOM   1381 C CA  . ASN A 1 190 ? -15.812 4.808   18.264  1.000 20.472 0 225 ASN A CA  1 ? 
ATOM   1382 C C   . ASN A 1 190 ? -16.781 4.712   19.432  1.000 20.009 0 225 ASN A C   1 ? 
ATOM   1383 O O   . ASN A 1 190 ? -17.979 4.937   19.245  1.000 20.023 0 225 ASN A O   1 ? 
ATOM   1384 C CB  . ASN A 1 190 ? -16.275 4.003   17.050  1.000 21.845 0 225 ASN A CB  1 ? 
ATOM   1385 C CG  . ASN A 1 190 ? -15.569 4.477   15.792  1.000 23.458 0 225 ASN A CG  1 ? 
ATOM   1386 O OD1 . ASN A 1 190 ? -15.838 5.571   15.312  1.000 22.592 0 225 ASN A OD1 1 ? 
ATOM   1387 N ND2 . ASN A 1 190 ? -14.629 3.693   15.297  1.000 26.945 0 225 ASN A ND2 1 ? 
ATOM   1388 N N   . LEU A 1 191 ? -16.290 4.369   20.628  1.000 21.263 0 226 LEU A N   1 ? 
ATOM   1389 C CA  . LEU A 1 191 ? -17.151 4.344   21.805  1.000 21.185 0 226 LEU A CA  1 ? 
ATOM   1390 C C   . LEU A 1 191 ? -17.561 5.772   22.159  1.000 20.713 0 226 LEU A C   1 ? 
ATOM   1391 O O   . LEU A 1 191 ? -16.831 6.707   21.851  1.000 20.151 0 226 LEU A O   1 ? 
ATOM   1392 C CB  . LEU A 1 191 ? -16.410 3.713   22.985  1.000 22.403 0 226 LEU A CB  1 ? 
ATOM   1393 C CG  . LEU A 1 191 ? -16.197 2.204   22.907  1.000 21.387 0 226 LEU A CG  1 ? 
ATOM   1394 C CD1 . LEU A 1 191 ? -15.302 1.734   24.055  1.000 21.187 0 226 LEU A CD1 1 ? 
ATOM   1395 C CD2 . LEU A 1 191 ? -17.538 1.479   22.901  1.000 21.113 0 226 LEU A CD2 1 ? 
ATOM   1396 N N   . PRO A 1 192 ? -18.733 5.986   22.800  1.000 20.802 0 227 PRO A N   1 ? 
ATOM   1397 C CA  . PRO A 1 192 ? -19.137 7.332   23.217  1.000 21.430 0 227 PRO A CA  1 ? 
ATOM   1398 C C   . PRO A 1 192 ? -18.093 7.975   24.120  1.000 22.311 0 227 PRO A C   1 ? 
ATOM   1399 O O   . PRO A 1 192 ? -17.299 7.293   24.782  1.000 20.723 0 227 PRO A O   1 ? 
ATOM   1400 C CB  . PRO A 1 192 ? -20.482 7.128   23.929  1.000 21.867 0 227 PRO A CB  1 ? 
ATOM   1401 C CG  . PRO A 1 192 ? -21.004 5.807   23.344  1.000 21.456 0 227 PRO A CG  1 ? 
ATOM   1402 C CD  . PRO A 1 192 ? -19.755 4.974   23.117  1.000 20.256 0 227 PRO A CD  1 ? 
ATOM   1403 N N   . LYS A 1 193 ? -18.126 9.314   24.114  1.000 23.536 0 228 LYS A N   1 ? 
ATOM   1404 C CA  . LYS A 1 193 ? -17.095 10.172  24.674  1.000 25.023 0 228 LYS A CA  1 ? 
ATOM   1405 C C   . LYS A 1 193 ? -16.978 9.972   26.187  1.000 21.578 0 228 LYS A C   1 ? 
ATOM   1406 O O   . LYS A 1 193 ? -15.891 10.052  26.733  1.000 20.859 0 228 LYS A O   1 ? 
ATOM   1407 C CB  . LYS A 1 193 ? -17.433 11.602  24.227  1.000 31.631 0 228 LYS A CB  1 ? 
ATOM   1408 C CG  . LYS A 1 193 ? -17.038 12.765  25.125  1.000 39.587 0 228 LYS A CG  1 ? 
ATOM   1409 C CD  . LYS A 1 193 ? -18.087 13.899  25.085  1.000 45.440 0 228 LYS A CD  1 ? 
ATOM   1410 C CE  . LYS A 1 193 ? -17.559 15.249  25.525  1.000 46.833 0 228 LYS A CE  1 ? 
ATOM   1411 N NZ  . LYS A 1 193 ? -16.933 15.194  26.868  1.000 46.163 0 228 LYS A NZ  1 ? 
ATOM   1412 N N   . ASP A 1 194 ? -18.086 9.683   26.871  1.000 20.632 0 229 ASP A N   1 ? 
ATOM   1413 C CA  . ASP A 1 194 ? -18.083 9.615   28.327  1.000 20.320 0 229 ASP A CA  1 ? 
ATOM   1414 C C   . ASP A 1 194 ? -17.895 8.179   28.818  1.000 20.114 0 229 ASP A C   1 ? 
ATOM   1415 O O   . ASP A 1 194 ? -17.796 7.980   30.029  1.000 21.503 0 229 ASP A O   1 ? 
ATOM   1416 C CB  . ASP A 1 194 ? -19.377 10.217  28.882  1.000 22.109 0 229 ASP A CB  1 ? 
ATOM   1417 C CG  . ASP A 1 194 ? -19.498 11.727  28.698  1.000 24.621 0 229 ASP A CG  1 ? 
ATOM   1418 O OD1 . ASP A 1 194 ? -18.437 12.410  28.654  1.000 26.413 0 229 ASP A OD1 1 ? 
ATOM   1419 O OD2 . ASP A 1 194 ? -20.640 12.204  28.563  1.000 22.030 0 229 ASP A OD2 1 ? 
ATOM   1420 N N   . THR A 1 195 ? -17.823 7.192   27.908  1.000 17.468 0 230 THR A N   1 ? 
ATOM   1421 C CA  . THR A 1 195 ? -17.758 5.800   28.345  1.000 17.861 0 230 THR A CA  1 ? 
ATOM   1422 C C   . THR A 1 195 ? -16.375 5.486   28.941  1.000 16.615 0 230 THR A C   1 ? 
ATOM   1423 O O   . THR A 1 195 ? -15.350 5.814   28.334  1.000 15.502 0 230 THR A O   1 ? 
ATOM   1424 C CB  . THR A 1 195 ? -18.152 4.853   27.201  1.000 16.916 0 230 THR A CB  1 ? 
ATOM   1425 O OG1 . THR A 1 195 ? -19.485 5.174   26.802  1.000 17.195 0 230 THR A OG1 1 ? 
ATOM   1426 C CG2 . THR A 1 195 ? -18.084 3.397   27.595  1.000 16.509 0 230 THR A CG2 1 ? 
ATOM   1427 N N   . PRO A 1 196 ? -16.281 4.868   30.149  1.000 15.816 0 231 PRO A N   1 ? 
ATOM   1428 C CA  . PRO A 1 196 ? -14.995 4.393   30.673  1.000 17.221 0 231 PRO A CA  1 ? 
ATOM   1429 C C   . PRO A 1 196 ? -14.447 3.301   29.755  1.000 17.271 0 231 PRO A C   1 ? 
ATOM   1430 O O   . PRO A 1 196 ? -15.185 2.386   29.390  1.000 15.644 0 231 PRO A O   1 ? 
ATOM   1431 C CB  . PRO A 1 196 ? -15.317 3.837   32.066  1.000 16.636 0 231 PRO A CB  1 ? 
ATOM   1432 C CG  . PRO A 1 196 ? -16.612 4.537   32.436  1.000 16.516 0 231 PRO A CG  1 ? 
ATOM   1433 C CD  . PRO A 1 196 ? -17.362 4.642   31.122  1.000 17.293 0 231 PRO A CD  1 ? 
ATOM   1434 N N   . LYS A 1 197 ? -13.193 3.450   29.314  1.000 17.106 0 232 LYS A N   1 ? 
ATOM   1435 C CA  . LYS A 1 197 ? -12.675 2.547   28.298  1.000 17.544 0 232 LYS A CA  1 ? 
ATOM   1436 C C   . LYS A 1 197 ? -11.160 2.415   28.383  1.000 16.217 0 232 LYS A C   1 ? 
ATOM   1437 O O   . LYS A 1 197 ? -10.478 3.363   28.741  1.000 16.084 0 232 LYS A O   1 ? 
ATOM   1438 C CB  . LYS A 1 197 ? -13.129 3.000   26.909  1.000 18.614 0 232 LYS A CB  1 ? 
ATOM   1439 C CG  . LYS A 1 197 ? -12.817 4.434   26.521  1.000 21.694 0 232 LYS A CG  1 ? 
ATOM   1440 C CD  . LYS A 1 197 ? -13.232 4.753   25.089  1.000 25.263 0 232 LYS A CD  1 ? 
ATOM   1441 C CE  . LYS A 1 197 ? -12.606 6.003   24.507  1.000 30.557 0 232 LYS A CE  1 ? 
ATOM   1442 N NZ  . LYS A 1 197 ? -12.803 6.141   23.030  1.000 35.239 0 232 LYS A NZ  1 ? 
ATOM   1443 N N   . ILE A 1 198 ? -10.677 1.203   28.067  1.000 16.441 0 233 ILE A N   1 ? 
ATOM   1444 C CA  . ILE A 1 198 ? -9.263  0.906   27.889  1.000 16.891 0 233 ILE A CA  1 ? 
ATOM   1445 C C   . ILE A 1 198 ? -9.069  0.155   26.568  1.000 17.071 0 233 ILE A C   1 ? 
ATOM   1446 O O   . ILE A 1 198 ? -9.852  -0.725  26.189  1.000 17.217 0 233 ILE A O   1 ? 
ATOM   1447 C CB  . ILE A 1 198 ? -8.685  0.095   29.066  1.000 16.891 0 233 ILE A CB  1 ? 
ATOM   1448 C CG1 . ILE A 1 198 ? -8.470  0.967   30.299  1.000 17.953 0 233 ILE A CG1 1 ? 
ATOM   1449 C CG2 . ILE A 1 198 ? -7.398  -0.590  28.646  1.000 17.345 0 233 ILE A CG2 1 ? 
ATOM   1450 C CD1 . ILE A 1 198 ? -7.972  0.203   31.517  1.000 19.365 0 233 ILE A CD1 1 ? 
ATOM   1451 N N   . TYR A 1 199 ? -7.984  0.520   25.894  1.000 16.485 0 234 TYR A N   1 ? 
ATOM   1452 C CA  . TYR A 1 199 ? -7.425  -0.241  24.795  1.000 16.811 0 234 TYR A CA  1 ? 
ATOM   1453 C C   . TYR A 1 199 ? -6.044  -0.684  25.245  1.000 16.187 0 234 TYR A C   1 ? 
ATOM   1454 O O   . TYR A 1 199 ? -5.235  0.177   25.579  1.000 17.074 0 234 TYR A O   1 ? 
ATOM   1455 C CB  . TYR A 1 199 ? -7.372  0.661   23.560  1.000 17.237 0 234 TYR A CB  1 ? 
ATOM   1456 C CG  . TYR A 1 199 ? -6.590  0.154   22.384  1.000 16.960 0 234 TYR A CG  1 ? 
ATOM   1457 C CD1 . TYR A 1 199 ? -7.136  -0.812  21.556  1.000 16.637 0 234 TYR A CD1 1 ? 
ATOM   1458 C CD2 . TYR A 1 199 ? -5.332  0.660   22.066  1.000 17.033 0 234 TYR A CD2 1 ? 
ATOM   1459 C CE1 . TYR A 1 199 ? -6.459  -1.279  20.448  1.000 16.710 0 234 TYR A CE1 1 ? 
ATOM   1460 C CE2 . TYR A 1 199 ? -4.636  0.207   20.952  1.000 16.637 0 234 TYR A CE2 1 ? 
ATOM   1461 C CZ  . TYR A 1 199 ? -5.206  -0.761  20.135  1.000 18.021 0 234 TYR A CZ  1 ? 
ATOM   1462 O OH  . TYR A 1 199 ? -4.577  -1.220  18.994  1.000 16.395 0 234 TYR A OH  1 ? 
ATOM   1463 N N   . ALA A 1 200 ? -5.827  -2.002  25.355  1.000 15.674 0 235 ALA A N   1 ? 
ATOM   1464 C CA  . ALA A 1 200 ? -4.554  -2.563  25.775  1.000 16.904 0 235 ALA A CA  1 ? 
ATOM   1465 C C   . ALA A 1 200 ? -4.133  -3.606  24.757  1.000 18.028 0 235 ALA A C   1 ? 
ATOM   1466 O O   . ALA A 1 200 ? -4.938  -4.460  24.417  1.000 17.536 0 235 ALA A O   1 ? 
ATOM   1467 C CB  . ALA A 1 200 ? -4.682  -3.183  27.148  1.000 18.314 0 235 ALA A CB  1 ? 
ATOM   1468 N N   . VAL A 1 201 ? -2.881  -3.541  24.276  1.000 18.482 0 236 VAL A N   1 ? 
ATOM   1469 C CA  . VAL A 1 201 ? -2.418  -4.489  23.274  1.000 18.519 0 236 VAL A CA  1 ? 
ATOM   1470 C C   . VAL A 1 201 ? -1.276  -5.318  23.851  1.000 18.211 0 236 VAL A C   1 ? 
ATOM   1471 O O   . VAL A 1 201 ? -0.266  -4.765  24.272  1.000 16.828 0 236 VAL A O   1 ? 
ATOM   1472 C CB  . VAL A 1 201 ? -2.014  -3.790  21.959  1.000 20.250 0 236 VAL A CB  1 ? 
ATOM   1473 C CG1 . VAL A 1 201 ? -1.511  -4.798  20.934  1.000 19.498 0 236 VAL A CG1 1 ? 
ATOM   1474 C CG2 . VAL A 1 201 ? -3.172  -2.996  21.367  1.000 20.986 0 236 VAL A CG2 1 ? 
ATOM   1475 N N   . LEU A 1 202 ? -1.464  -6.645  23.866  1.000 19.214 0 237 LEU A N   1 ? 
ATOM   1476 C CA  . LEU A 1 202 ? -0.468  -7.578  24.376  1.000 21.010 0 237 LEU A CA  1 ? 
ATOM   1477 C C   . LEU A 1 202 ? 0.707   -7.639  23.394  1.000 20.466 0 237 LEU A C   1 ? 
ATOM   1478 O O   . LEU A 1 202 ? 0.492   -7.946  22.222  1.000 18.563 0 237 LEU A O   1 ? 
ATOM   1479 C CB  . LEU A 1 202 ? -1.127  -8.956  24.541  1.000 21.253 0 237 LEU A CB  1 ? 
ATOM   1480 C CG  . LEU A 1 202 ? -2.280  -9.057  25.547  1.000 23.350 0 237 LEU A CG  1 ? 
ATOM   1481 C CD1 . LEU A 1 202 ? -2.997  -10.395 25.417  1.000 23.656 0 237 LEU A CD1 1 ? 
ATOM   1482 C CD2 . LEU A 1 202 ? -1.807  -8.839  26.987  1.000 23.997 0 237 LEU A CD2 1 ? 
ATOM   1483 N N   . CYS A 1 203 ? 1.939   -7.362  23.876  1.000 21.380 0 238 CYS A N   1 ? 
ATOM   1484 C CA  . CYS A 1 203 ? 3.127   -7.407  23.023  1.000 22.374 0 238 CYS A CA  1 ? 
ATOM   1485 C C   . CYS A 1 203 ? 3.316   -8.813  22.462  1.000 20.435 0 238 CYS A C   1 ? 
ATOM   1486 O O   . CYS A 1 203 ? 3.238   -9.770  23.204  1.000 17.874 0 238 CYS A O   1 ? 
ATOM   1487 C CB  . CYS A 1 203 ? 4.430   -7.088  23.752  1.000 23.769 0 238 CYS A CB  1 ? 
ATOM   1488 S SG  . CYS A 1 203 ? 4.621   -5.353  24.208  1.000 28.977 0 238 CYS A SG  1 ? 
ATOM   1489 N N   . ASN A 1 204 ? 3.535   -8.895  21.151  1.000 23.046 0 239 ASN A N   1 ? 
ATOM   1490 C CA  . ASN A 1 204 ? 3.973   -10.102 20.473  1.000 26.822 0 239 ASN A CA  1 ? 
ATOM   1491 C C   . ASN A 1 204 ? 2.966   -11.250 20.614  1.000 24.928 0 239 ASN A C   1 ? 
ATOM   1492 O O   . ASN A 1 204 ? 3.346   -12.401 20.513  1.000 27.873 0 239 ASN A O   1 ? 
ATOM   1493 C CB  . ASN A 1 204 ? 5.362   -10.512 20.979  1.000 29.554 0 239 ASN A CB  1 ? 
ATOM   1494 C CG  . ASN A 1 204 ? 6.166   -11.256 19.925  1.000 36.875 0 239 ASN A CG  1 ? 
ATOM   1495 O OD1 . ASN A 1 204 ? 5.921   -11.099 18.724  1.000 42.706 0 239 ASN A OD1 1 ? 
ATOM   1496 N ND2 . ASN A 1 204 ? 7.129   -12.065 20.351  1.000 33.964 0 239 ASN A ND2 1 ? 
ATOM   1497 N N   . ALA A 1 205 ? 1.682   -10.967 20.818  1.000 24.176 0 240 ALA A N   1 ? 
ATOM   1498 C CA  . ALA A 1 205 ? 0.701   -12.018 21.071  1.000 19.567 0 240 ALA A CA  1 ? 
ATOM   1499 C C   . ALA A 1 205 ? -0.089  -12.295 19.793  1.000 19.470 0 240 ALA A C   1 ? 
ATOM   1500 O O   . ALA A 1 205 ? -0.270  -11.400 18.952  1.000 17.446 0 240 ALA A O   1 ? 
ATOM   1501 C CB  . ALA A 1 205 ? -0.214  -11.606 22.196  1.000 19.395 0 240 ALA A CB  1 ? 
ATOM   1502 N N   . SER A 1 206 ? -0.564  -13.553 19.696  1.000 18.740 0 241 SER A N   1 ? 
ATOM   1503 C CA  . SER A 1 206 ? -1.496  -14.004 18.673  1.000 17.548 0 241 SER A CA  1 ? 
ATOM   1504 C C   . SER A 1 206 ? -2.943  -13.788 19.122  1.000 17.333 0 241 SER A C   1 ? 
ATOM   1505 O O   . SER A 1 206 ? -3.225  -13.509 20.293  1.000 19.006 0 241 SER A O   1 ? 
ATOM   1506 C CB  . SER A 1 206 ? -1.303  -15.462 18.369  1.000 17.618 0 241 SER A CB  1 ? 
ATOM   1507 O OG  . SER A 1 206 ? -1.899  -16.278 19.384  1.000 17.111 0 241 SER A OG  1 ? 
ATOM   1508 N N   . HIS A 1 207 ? -3.848  -14.018 18.169  1.000 16.085 0 242 HIS A N   1 ? 
ATOM   1509 C CA  . HIS A 1 207 ? -5.287  -14.004 18.381  1.000 15.649 0 242 HIS A CA  1 ? 
ATOM   1510 C C   . HIS A 1 207 ? -5.706  -14.936 19.532  1.000 16.019 0 242 HIS A C   1 ? 
ATOM   1511 O O   . HIS A 1 207 ? -6.728  -14.696 20.164  1.000 15.739 0 242 HIS A O   1 ? 
ATOM   1512 C CB  . HIS A 1 207 ? -5.967  -14.355 17.054  1.000 15.226 0 242 HIS A CB  1 ? 
ATOM   1513 C CG  . HIS A 1 207 ? -7.448  -14.184 17.042  1.000 14.676 0 242 HIS A CG  1 ? 
ATOM   1514 N ND1 . HIS A 1 207 ? -8.060  -12.946 17.118  1.000 14.555 0 242 HIS A ND1 1 ? 
ATOM   1515 C CD2 . HIS A 1 207 ? -8.438  -15.095 16.940  1.000 15.274 0 242 HIS A CD2 1 ? 
ATOM   1516 C CE1 . HIS A 1 207 ? -9.390  -13.105 17.084  1.000 15.359 0 242 HIS A CE1 1 ? 
ATOM   1517 N NE2 . HIS A 1 207 ? -9.654  -14.397 16.964  1.000 15.283 0 242 HIS A NE2 1 ? 
ATOM   1518 N N   . ILE A 1 208 ? -4.927  -15.993 19.825  1.000 16.521 0 243 ILE A N   1 ? 
ATOM   1519 C CA  . ILE A 1 208 ? -5.350  -17.009 20.784  1.000 16.816 0 243 ILE A CA  1 ? 
ATOM   1520 C C   . ILE A 1 208 ? -4.565  -16.917 22.095  1.000 16.872 0 243 ILE A C   1 ? 
ATOM   1521 O O   . ILE A 1 208 ? -4.700  -17.804 22.941  1.000 16.082 0 243 ILE A O   1 ? 
ATOM   1522 C CB  . ILE A 1 208 ? -5.306  -18.423 20.171  1.000 17.578 0 243 ILE A CB  1 ? 
ATOM   1523 C CG1 . ILE A 1 208 ? -3.908  -18.828 19.703  1.000 18.954 0 243 ILE A CG1 1 ? 
ATOM   1524 C CG2 . ILE A 1 208 ? -6.325  -18.546 19.049  1.000 17.244 0 243 ILE A CG2 1 ? 
ATOM   1525 C CD1 . ILE A 1 208 ? -3.773  -20.310 19.470  1.000 19.050 0 243 ILE A CD1 1 ? 
ATOM   1526 N N   . ALA A 1 209 ? -3.815  -15.816 22.294  1.000 17.308 0 244 ALA A N   1 ? 
ATOM   1527 C CA  . ALA A 1 209 ? -3.253  -15.472 23.598  1.000 17.809 0 244 ALA A CA  1 ? 
ATOM   1528 C C   . ALA A 1 209 ? -4.285  -15.639 24.715  1.000 17.124 0 244 ALA A C   1 ? 
ATOM   1529 O O   . ALA A 1 209 ? -3.940  -16.119 25.795  1.000 15.985 0 244 ALA A O   1 ? 
ATOM   1530 C CB  . ALA A 1 209 ? -2.694  -14.066 23.609  1.000 18.104 0 244 ALA A CB  1 ? 
ATOM   1531 N N   . PRO A 1 210 ? -5.561  -15.211 24.532  1.000 16.836 0 245 PRO A N   1 ? 
ATOM   1532 C CA  . PRO A 1 210 ? -6.567  -15.366 25.593  1.000 17.079 0 245 PRO A CA  1 ? 
ATOM   1533 C C   . PRO A 1 210 ? -6.929  -16.783 26.051  1.000 17.567 0 245 PRO A C   1 ? 
ATOM   1534 O O   . PRO A 1 210 ? -7.481  -16.937 27.143  1.000 16.635 0 245 PRO A O   1 ? 
ATOM   1535 C CB  . PRO A 1 210 ? -7.794  -14.646 25.008  1.000 16.903 0 245 PRO A CB  1 ? 
ATOM   1536 C CG  . PRO A 1 210 ? -7.192  -13.614 24.069  1.000 16.381 0 245 PRO A CG  1 ? 
ATOM   1537 C CD  . PRO A 1 210 ? -6.043  -14.367 23.419  1.000 16.733 0 245 PRO A CD  1 ? 
ATOM   1538 N N   . ASN A 1 211 ? -6.569  -17.795 25.243  1.000 17.422 0 246 ASN A N   1 ? 
ATOM   1539 C CA  . ASN A 1 211 ? -6.861  -19.185 25.541  1.000 18.325 0 246 ASN A CA  1 ? 
ATOM   1540 C C   . ASN A 1 211 ? -5.801  -19.825 26.435  1.000 18.451 0 246 ASN A C   1 ? 
ATOM   1541 O O   . ASN A 1 211 ? -5.957  -20.983 26.806  1.000 15.256 0 246 ASN A O   1 ? 
ATOM   1542 C CB  . ASN A 1 211 ? -7.009  -20.013 24.254  1.000 19.391 0 246 ASN A CB  1 ? 
ATOM   1543 C CG  . ASN A 1 211 ? -8.162  -19.530 23.401  1.000 19.595 0 246 ASN A CG  1 ? 
ATOM   1544 O OD1 . ASN A 1 211 ? -8.022  -19.359 22.189  1.000 19.962 0 246 ASN A OD1 1 ? 
ATOM   1545 N ND2 . ASN A 1 211 ? -9.305  -19.304 24.028  1.000 17.707 0 246 ASN A ND2 1 ? 
ATOM   1546 N N   . SER A 1 212 ? -4.716  -19.091 26.743  1.000 18.662 0 247 SER A N   1 ? 
ATOM   1547 C CA  A SER A 1 212 ? -3.692  -19.548 27.668  0.500 18.392 0 247 SER A CA  1 ? 
ATOM   1548 C CA  B SER A 1 212 ? -3.699  -19.550 27.674  0.500 19.523 0 247 SER A CA  1 ? 
ATOM   1549 C C   . SER A 1 212 ? -3.544  -18.552 28.817  1.000 18.978 0 247 SER A C   1 ? 
ATOM   1550 O O   . SER A 1 212 ? -3.658  -17.337 28.619  1.000 16.995 0 247 SER A O   1 ? 
ATOM   1551 C CB  A SER A 1 212 ? -2.366  -19.752 26.970  0.500 18.391 0 247 SER A CB  1 ? 
ATOM   1552 C CB  B SER A 1 212 ? -2.372  -19.788 26.994  0.500 20.882 0 247 SER A CB  1 ? 
ATOM   1553 O OG  A SER A 1 212 ? -2.486  -20.624 25.845  0.500 16.927 0 247 SER A OG  1 ? 
ATOM   1554 O OG  B SER A 1 212 ? -1.936  -18.647 26.269  0.500 22.591 0 247 SER A OG  1 ? 
ATOM   1555 N N   . ASN A 1 213 ? -3.245  -19.103 30.000  1.000 19.584 0 248 ASN A N   1 ? 
ATOM   1556 C CA  . ASN A 1 213 ? -3.044  -18.361 31.232  1.000 21.052 0 248 ASN A CA  1 ? 
ATOM   1557 C C   . ASN A 1 213 ? -2.117  -17.187 30.936  1.000 21.349 0 248 ASN A C   1 ? 
ATOM   1558 O O   . ASN A 1 213 ? -1.033  -17.391 30.406  1.000 19.677 0 248 ASN A O   1 ? 
ATOM   1559 C CB  . ASN A 1 213 ? -2.451  -19.275 32.302  1.000 24.332 0 248 ASN A CB  1 ? 
ATOM   1560 C CG  . ASN A 1 213 ? -2.632  -18.717 33.693  1.000 27.218 0 248 ASN A CG  1 ? 
ATOM   1561 O OD1 . ASN A 1 213 ? -2.309  -17.559 33.944  1.000 32.717 0 248 ASN A OD1 1 ? 
ATOM   1562 N ND2 . ASN A 1 213 ? -3.235  -19.500 34.572  1.000 28.029 0 248 ASN A ND2 1 ? 
ATOM   1563 N N   . ASN A 1 214 ? -2.565  -15.962 31.213  1.000 20.174 0 249 ASN A N   1 ? 
ATOM   1564 C CA  . ASN A 1 214 ? -1.853  -14.781 30.758  1.000 21.036 0 249 ASN A CA  1 ? 
ATOM   1565 C C   . ASN A 1 214 ? -1.853  -13.735 31.875  1.000 21.703 0 249 ASN A C   1 ? 
ATOM   1566 O O   . ASN A 1 214 ? -2.923  -13.337 32.353  1.000 22.156 0 249 ASN A O   1 ? 
ATOM   1567 C CB  . ASN A 1 214 ? -2.492  -14.268 29.463  1.000 20.183 0 249 ASN A CB  1 ? 
ATOM   1568 C CG  . ASN A 1 214 ? -1.797  -13.055 28.891  1.000 20.813 0 249 ASN A CG  1 ? 
ATOM   1569 O OD1 . ASN A 1 214 ? -1.878  -11.956 29.429  1.000 21.291 0 249 ASN A OD1 1 ? 
ATOM   1570 N ND2 . ASN A 1 214 ? -1.134  -13.238 27.769  1.000 19.449 0 249 ASN A ND2 1 ? 
ATOM   1571 N N   . ALA A 1 215 ? -0.654  -13.284 32.276  1.000 19.865 0 250 ALA A N   1 ? 
ATOM   1572 C CA  . ALA A 1 215 ? -0.510  -12.392 33.420  1.000 19.537 0 250 ALA A CA  1 ? 
ATOM   1573 C C   . ALA A 1 215 ? -1.268  -11.077 33.212  1.000 17.894 0 250 ALA A C   1 ? 
ATOM   1574 O O   . ALA A 1 215 ? -1.995  -10.613 34.090  1.000 18.393 0 250 ALA A O   1 ? 
ATOM   1575 C CB  . ALA A 1 215 ? 0.956   -12.146 33.696  1.000 20.303 0 250 ALA A CB  1 ? 
ATOM   1576 N N   . ALA A 1 216 ? -1.094  -10.459 32.040  1.000 17.014 0 251 ALA A N   1 ? 
ATOM   1577 C CA  . ALA A 1 216 ? -1.728  -9.176  31.768  1.000 16.811 0 251 ALA A CA  1 ? 
ATOM   1578 C C   . ALA A 1 216 ? -3.254  -9.284  31.778  1.000 16.779 0 251 ALA A C   1 ? 
ATOM   1579 O O   . ALA A 1 216 ? -3.947  -8.416  32.314  1.000 16.962 0 251 ALA A O   1 ? 
ATOM   1580 C CB  . ALA A 1 216 ? -1.227  -8.654  30.455  1.000 17.550 0 251 ALA A CB  1 ? 
ATOM   1581 N N   . ILE A 1 217 ? -3.780  -10.351 31.184  1.000 16.367 0 252 ILE A N   1 ? 
ATOM   1582 C CA  . ILE A 1 217 ? -5.218  -10.553 31.133  1.000 18.369 0 252 ILE A CA  1 ? 
ATOM   1583 C C   . ILE A 1 217 ? -5.767  -10.709 32.545  1.000 18.711 0 252 ILE A C   1 ? 
ATOM   1584 O O   . ILE A 1 217 ? -6.807  -10.125 32.846  1.000 19.559 0 252 ILE A O   1 ? 
ATOM   1585 C CB  . ILE A 1 217 ? -5.590  -11.733 30.217  1.000 18.678 0 252 ILE A CB  1 ? 
ATOM   1586 C CG1 . ILE A 1 217 ? -5.253  -11.386 28.766  1.000 20.019 0 252 ILE A CG1 1 ? 
ATOM   1587 C CG2 . ILE A 1 217 ? -7.063  -12.114 30.379  1.000 19.643 0 252 ILE A CG2 1 ? 
ATOM   1588 C CD1 . ILE A 1 217 ? -5.565  -12.471 27.759  1.000 21.385 0 252 ILE A CD1 1 ? 
ATOM   1589 N N   . LYS A 1 218 ? -5.060  -11.480 33.394  1.000 17.905 0 253 LYS A N   1 ? 
ATOM   1590 C CA  . LYS A 1 218 ? -5.419  -11.622 34.793  1.000 18.901 0 253 LYS A CA  1 ? 
ATOM   1591 C C   . LYS A 1 218 ? -5.487  -10.253 35.464  1.000 19.149 0 253 LYS A C   1 ? 
ATOM   1592 O O   . LYS A 1 218 ? -6.467  -9.961  36.127  1.000 19.727 0 253 LYS A O   1 ? 
ATOM   1593 C CB  . LYS A 1 218 ? -4.446  -12.557 35.527  1.000 20.243 0 253 LYS A CB  1 ? 
ATOM   1594 C CG  . LYS A 1 218 ? -4.589  -14.025 35.130  1.000 20.541 0 253 LYS A CG  1 ? 
ATOM   1595 C CD  . LYS A 1 218 ? -3.651  -14.977 35.819  1.000 23.138 0 253 LYS A CD  1 ? 
ATOM   1596 C CE  . LYS A 1 218 ? -2.204  -14.809 35.410  1.000 26.322 0 253 LYS A CE  1 ? 
ATOM   1597 N NZ  . LYS A 1 218 ? -1.320  -15.815 36.069  1.000 28.722 0 253 LYS A NZ  1 ? 
ATOM   1598 N N   . ILE A 1 219 ? -4.449  -9.424  35.291  1.000 18.774 0 254 ILE A N   1 ? 
ATOM   1599 C CA  . ILE A 1 219 ? -4.364  -8.153  35.998  1.000 18.298 0 254 ILE A CA  1 ? 
ATOM   1600 C C   . ILE A 1 219 ? -5.494  -7.223  35.561  1.000 16.809 0 254 ILE A C   1 ? 
ATOM   1601 O O   . ILE A 1 219 ? -6.199  -6.665  36.401  1.000 17.460 0 254 ILE A O   1 ? 
ATOM   1602 C CB  . ILE A 1 219 ? -2.973  -7.523  35.769  1.000 18.560 0 254 ILE A CB  1 ? 
ATOM   1603 C CG1 . ILE A 1 219 ? -1.903  -8.345  36.490  1.000 18.019 0 254 ILE A CG1 1 ? 
ATOM   1604 C CG2 . ILE A 1 219 ? -2.957  -6.052  36.179  1.000 19.304 0 254 ILE A CG2 1 ? 
ATOM   1605 C CD1 . ILE A 1 219 ? -0.525  -8.150  35.937  1.000 19.305 0 254 ILE A CD1 1 ? 
ATOM   1606 N N   . TYR A 1 220 ? -5.673  -7.061  34.249  1.000 17.310 0 255 TYR A N   1 ? 
ATOM   1607 C CA  . TYR A 1 220 ? -6.598  -6.058  33.729  1.000 18.040 0 255 TYR A CA  1 ? 
ATOM   1608 C C   . TYR A 1 220 ? -8.062  -6.515  33.881  1.000 18.598 0 255 TYR A C   1 ? 
ATOM   1609 O O   . TYR A 1 220 ? -8.930  -5.702  34.219  1.000 16.714 0 255 TYR A O   1 ? 
ATOM   1610 C CB  . TYR A 1 220 ? -6.150  -5.614  32.332  1.000 19.410 0 255 TYR A CB  1 ? 
ATOM   1611 C CG  . TYR A 1 220 ? -4.801  -4.925  32.365  1.000 20.784 0 255 TYR A CG  1 ? 
ATOM   1612 C CD1 . TYR A 1 220 ? -4.635  -3.686  32.970  1.000 21.759 0 255 TYR A CD1 1 ? 
ATOM   1613 C CD2 . TYR A 1 220 ? -3.675  -5.535  31.839  1.000 21.547 0 255 TYR A CD2 1 ? 
ATOM   1614 C CE1 . TYR A 1 220 ? -3.386  -3.082  33.050  1.000 23.379 0 255 TYR A CE1 1 ? 
ATOM   1615 C CE2 . TYR A 1 220 ? -2.415  -4.963  31.934  1.000 23.390 0 255 TYR A CE2 1 ? 
ATOM   1616 C CZ  . TYR A 1 220 ? -2.268  -3.738  32.562  1.000 24.028 0 255 TYR A CZ  1 ? 
ATOM   1617 O OH  . TYR A 1 220 ? -1.010  -3.189  32.654  1.000 24.375 0 255 TYR A OH  1 ? 
ATOM   1618 N N   . THR A 1 221 ? -8.351  -7.813  33.701  1.000 19.422 0 256 THR A N   1 ? 
ATOM   1619 C CA  A THR A 1 221 ? -9.733  -8.279  33.767  0.500 17.909 0 256 THR A CA  1 ? 
ATOM   1620 C CA  B THR A 1 221 ? -9.726  -8.296  33.765  0.500 19.181 0 256 THR A CA  1 ? 
ATOM   1621 C C   . THR A 1 221 ? -10.213 -8.291  35.220  1.000 17.729 0 256 THR A C   1 ? 
ATOM   1622 O O   . THR A 1 221 ? -11.332 -7.813  35.513  1.000 16.490 0 256 THR A O   1 ? 
ATOM   1623 C CB  A THR A 1 221 ? -9.947  -9.634  33.074  0.500 17.467 0 256 THR A CB  1 ? 
ATOM   1624 C CB  B THR A 1 221 ? -9.832  -9.645  33.039  0.500 20.221 0 256 THR A CB  1 ? 
ATOM   1625 O OG1 A THR A 1 221 ? -9.237  -10.648 33.788  0.500 15.725 0 256 THR A OG1 1 ? 
ATOM   1626 O OG1 B THR A 1 221 ? -9.254  -9.472  31.745  0.500 21.958 0 256 THR A OG1 1 ? 
ATOM   1627 C CG2 A THR A 1 221 ? -9.578  -9.610  31.604  0.500 17.722 0 256 THR A CG2 1 ? 
ATOM   1628 C CG2 B THR A 1 221 ? -11.249 -10.138 32.859  0.500 20.888 0 256 THR A CG2 1 ? 
ATOM   1629 N N   . VAL A 1 222 ? -9.379  -8.806  36.150  1.000 16.634 0 257 VAL A N   1 ? 
ATOM   1630 C CA  . VAL A 1 222 ? -9.767  -8.789  37.556  1.000 16.760 0 257 VAL A CA  1 ? 
ATOM   1631 C C   . VAL A 1 222 ? -10.003 -7.344  38.019  1.000 16.155 0 257 VAL A C   1 ? 
ATOM   1632 O O   . VAL A 1 222 ? -11.034 -7.049  38.615  1.000 15.537 0 257 VAL A O   1 ? 
ATOM   1633 C CB  . VAL A 1 222 ? -8.762  -9.509  38.469  1.000 17.287 0 257 VAL A CB  1 ? 
ATOM   1634 C CG1 . VAL A 1 222 ? -9.044  -9.247  39.944  1.000 18.430 0 257 VAL A CG1 1 ? 
ATOM   1635 C CG2 . VAL A 1 222 ? -8.739  -11.003 38.200  1.000 18.204 0 257 VAL A CG2 1 ? 
ATOM   1636 N N   . SER A 1 223 ? -9.077  -6.435  37.703  1.000 15.469 0 258 SER A N   1 ? 
ATOM   1637 C CA  . SER A 1 223 ? -9.188  -5.035  38.097  1.000 15.777 0 258 SER A CA  1 ? 
ATOM   1638 C C   . SER A 1 223 ? -10.433 -4.363  37.512  1.000 16.841 0 258 SER A C   1 ? 
ATOM   1639 O O   . SER A 1 223 ? -11.164 -3.656  38.230  1.000 17.573 0 258 SER A O   1 ? 
ATOM   1640 C CB  . SER A 1 223 ? -7.939  -4.275  37.731  1.000 15.269 0 258 SER A CB  1 ? 
ATOM   1641 O OG  . SER A 1 223 ? -6.819  -4.842  38.387  1.000 14.865 0 258 SER A OG  1 ? 
ATOM   1642 N N   . TRP A 1 224 ? -10.692 -4.597  36.218  1.000 15.384 0 259 TRP A N   1 ? 
ATOM   1643 C CA  . TRP A 1 224 ? -11.861 -4.018  35.565  1.000 15.291 0 259 TRP A CA  1 ? 
ATOM   1644 C C   . TRP A 1 224 ? -13.158 -4.453  36.252  1.000 15.722 0 259 TRP A C   1 ? 
ATOM   1645 O O   . TRP A 1 224 ? -14.024 -3.628  36.528  1.000 14.686 0 259 TRP A O   1 ? 
ATOM   1646 C CB  . TRP A 1 224 ? -11.872 -4.399  34.085  1.000 15.316 0 259 TRP A CB  1 ? 
ATOM   1647 C CG  . TRP A 1 224 ? -12.726 -3.526  33.233  1.000 15.512 0 259 TRP A CG  1 ? 
ATOM   1648 C CD1 . TRP A 1 224 ? -13.926 -3.832  32.657  1.000 15.597 0 259 TRP A CD1 1 ? 
ATOM   1649 C CD2 . TRP A 1 224 ? -12.414 -2.184  32.824  1.000 16.178 0 259 TRP A CD2 1 ? 
ATOM   1650 N NE1 . TRP A 1 224 ? -14.367 -2.778  31.892  1.000 16.158 0 259 TRP A NE1 1 ? 
ATOM   1651 C CE2 . TRP A 1 224 ? -13.469 -1.751  31.981  1.000 16.045 0 259 TRP A CE2 1 ? 
ATOM   1652 C CE3 . TRP A 1 224 ? -11.319 -1.340  33.029  1.000 15.991 0 259 TRP A CE3 1 ? 
ATOM   1653 C CZ2 . TRP A 1 224 ? -13.469 -0.495  31.377  1.000 15.807 0 259 TRP A CZ2 1 ? 
ATOM   1654 C CZ3 . TRP A 1 224 ? -11.325 -0.099  32.433  1.000 16.392 0 259 TRP A CZ3 1 ? 
ATOM   1655 C CH2 . TRP A 1 224 ? -12.385 0.314   31.620  1.000 16.123 0 259 TRP A CH2 1 ? 
ATOM   1656 N N   . PHE A 1 225 ? -13.312 -5.770  36.472  1.000 15.886 0 260 PHE A N   1 ? 
ATOM   1657 C CA  . PHE A 1 225 ? -14.546 -6.304  37.029  1.000 15.791 0 260 PHE A CA  1 ? 
ATOM   1658 C C   . PHE A 1 225 ? -14.666 -5.919  38.503  1.000 15.580 0 260 PHE A C   1 ? 
ATOM   1659 O O   . PHE A 1 225 ? -15.754 -5.638  38.979  1.000 15.914 0 260 PHE A O   1 ? 
ATOM   1660 C CB  . PHE A 1 225 ? -14.615 -7.825  36.852  1.000 15.787 0 260 PHE A CB  1 ? 
ATOM   1661 C CG  . PHE A 1 225 ? -14.944 -8.259  35.451  1.000 16.002 0 260 PHE A CG  1 ? 
ATOM   1662 C CD1 . PHE A 1 225 ? -16.087 -7.786  34.815  1.000 15.214 0 260 PHE A CD1 1 ? 
ATOM   1663 C CD2 . PHE A 1 225 ? -14.124 -9.145  34.769  1.000 15.056 0 260 PHE A CD2 1 ? 
ATOM   1664 C CE1 . PHE A 1 225 ? -16.395 -8.184  33.516  1.000 16.195 0 260 PHE A CE1 1 ? 
ATOM   1665 C CE2 . PHE A 1 225 ? -14.435 -9.523  33.472  1.000 15.302 0 260 PHE A CE2 1 ? 
ATOM   1666 C CZ  . PHE A 1 225 ? -15.569 -9.045  32.850  1.000 15.053 0 260 PHE A CZ  1 ? 
ATOM   1667 N N   . LYS A 1 226 ? -13.549 -5.890  39.226  1.000 15.315 0 261 LYS A N   1 ? 
ATOM   1668 C CA  . LYS A 1 226 ? -13.577 -5.405  40.600  1.000 16.321 0 261 LYS A CA  1 ? 
ATOM   1669 C C   . LYS A 1 226 ? -13.996 -3.936  40.686  1.000 17.472 0 261 LYS A C   1 ? 
ATOM   1670 O O   . LYS A 1 226 ? -14.816 -3.562  41.541  1.000 17.206 0 261 LYS A O   1 ? 
ATOM   1671 C CB  . LYS A 1 226 ? -12.226 -5.626  41.262  1.000 16.443 0 261 LYS A CB  1 ? 
ATOM   1672 C CG  . LYS A 1 226 ? -12.016 -7.045  41.736  1.000 16.724 0 261 LYS A CG  1 ? 
ATOM   1673 C CD  . LYS A 1 226 ? -12.705 -7.343  43.058  1.000 17.521 0 261 LYS A CD  1 ? 
ATOM   1674 C CE  . LYS A 1 226 ? -12.516 -8.786  43.467  1.000 18.627 0 261 LYS A CE  1 ? 
ATOM   1675 N NZ  . LYS A 1 226 ? -13.111 -9.050  44.798  1.000 18.760 0 261 LYS A NZ  1 ? 
ATOM   1676 N N   . LEU A 1 227 ? -13.447 -3.096  39.815  1.000 17.510 0 262 LEU A N   1 ? 
ATOM   1677 C CA  . LEU A 1 227 ? -13.759 -1.680  39.915  1.000 18.647 0 262 LEU A CA  1 ? 
ATOM   1678 C C   . LEU A 1 227 ? -15.230 -1.427  39.549  1.000 18.325 0 262 LEU A C   1 ? 
ATOM   1679 O O   . LEU A 1 227 ? -15.925 -0.667  40.239  1.000 20.017 0 262 LEU A O   1 ? 
ATOM   1680 C CB  . LEU A 1 227 ? -12.806 -0.904  39.006  1.000 18.884 0 262 LEU A CB  1 ? 
ATOM   1681 C CG  . LEU A 1 227 ? -13.042 0.605   38.951  1.000 19.876 0 262 LEU A CG  1 ? 
ATOM   1682 C CD1 . LEU A 1 227 ? -12.840 1.252   40.328  1.000 20.984 0 262 LEU A CD1 1 ? 
ATOM   1683 C CD2 . LEU A 1 227 ? -12.128 1.236   37.907  1.000 19.702 0 262 LEU A CD2 1 ? 
ATOM   1684 N N   . PHE A 1 228 ? -15.688 -2.055  38.456  1.000 17.137 0 263 PHE A N   1 ? 
ATOM   1685 C CA  . PHE A 1 228 ? -16.958 -1.702  37.842  1.000 17.260 0 263 PHE A CA  1 ? 
ATOM   1686 C C   . PHE A 1 228 ? -18.104 -2.579  38.347  1.000 18.291 0 263 PHE A C   1 ? 
ATOM   1687 O O   . PHE A 1 228 ? -19.228 -2.077  38.458  1.000 16.865 0 263 PHE A O   1 ? 
ATOM   1688 C CB  . PHE A 1 228 ? -16.810 -1.695  36.323  1.000 16.794 0 263 PHE A CB  1 ? 
ATOM   1689 C CG  . PHE A 1 228 ? -16.019 -0.510  35.850  1.000 16.983 0 263 PHE A CG  1 ? 
ATOM   1690 C CD1 . PHE A 1 228 ? -16.518 0.772   36.026  1.000 17.609 0 263 PHE A CD1 1 ? 
ATOM   1691 C CD2 . PHE A 1 228 ? -14.761 -0.657  35.275  1.000 18.006 0 263 PHE A CD2 1 ? 
ATOM   1692 C CE1 . PHE A 1 228 ? -15.794 1.879   35.604  1.000 17.927 0 263 PHE A CE1 1 ? 
ATOM   1693 C CE2 . PHE A 1 228 ? -14.034 0.450   34.852  1.000 17.295 0 263 PHE A CE2 1 ? 
ATOM   1694 C CZ  . PHE A 1 228 ? -14.548 1.719   35.037  1.000 17.752 0 263 PHE A CZ  1 ? 
ATOM   1695 N N   . LEU A 1 229 ? -17.845 -3.864  38.653  1.000 16.705 0 264 LEU A N   1 ? 
ATOM   1696 C CA  . LEU A 1 229 ? -18.913 -4.705  39.175  1.000 18.903 0 264 LEU A CA  1 ? 
ATOM   1697 C C   . LEU A 1 229 ? -19.032 -4.528  40.682  1.000 19.236 0 264 LEU A C   1 ? 
ATOM   1698 O O   . LEU A 1 229 ? -20.148 -4.530  41.208  1.000 16.732 0 264 LEU A O   1 ? 
ATOM   1699 C CB  . LEU A 1 229 ? -18.694 -6.183  38.844  1.000 18.253 0 264 LEU A CB  1 ? 
ATOM   1700 C CG  . LEU A 1 229 ? -18.633 -6.536  37.357  1.000 18.014 0 264 LEU A CG  1 ? 
ATOM   1701 C CD1 . LEU A 1 229 ? -18.725 -8.050  37.147  1.000 17.123 0 264 LEU A CD1 1 ? 
ATOM   1702 C CD2 . LEU A 1 229 ? -19.710 -5.829  36.580  1.000 18.995 0 264 LEU A CD2 1 ? 
ATOM   1703 N N   . CYS A 1 230 ? -17.891 -4.394  41.372  1.000 18.432 0 265 CYS A N   1 ? 
ATOM   1704 C CA  . CYS A 1 230 ? -17.909 -4.417  42.827  1.000 19.590 0 265 CYS A CA  1 ? 
ATOM   1705 C C   . CYS A 1 230 ? -17.746 -3.032  43.427  1.000 19.681 0 265 CYS A C   1 ? 
ATOM   1706 O O   . CYS A 1 230 ? -17.807 -2.922  44.642  1.000 20.796 0 265 CYS A O   1 ? 
ATOM   1707 C CB  . CYS A 1 230 ? -16.785 -5.248  43.430  1.000 19.810 0 265 CYS A CB  1 ? 
ATOM   1708 S SG  . CYS A 1 230 ? -16.724 -6.925  42.789  1.000 23.714 0 265 CYS A SG  1 ? 
ATOM   1709 N N   . ASP A 1 231 ? -17.493 -2.018  42.598  1.000 20.493 0 266 ASP A N   1 ? 
ATOM   1710 C CA  . ASP A 1 231 ? -17.150 -0.686  43.068  1.000 24.018 0 266 ASP A CA  1 ? 
ATOM   1711 C C   . ASP A 1 231 ? -15.957 -0.749  44.015  1.000 23.045 0 266 ASP A C   1 ? 
ATOM   1712 O O   . ASP A 1 231 ? -15.916 0.006   44.988  1.000 20.787 0 266 ASP A O   1 ? 
ATOM   1713 C CB  . ASP A 1 231 ? -18.327 0.009   43.772  1.000 25.789 0 266 ASP A CB  1 ? 
ATOM   1714 C CG  . ASP A 1 231 ? -19.531 0.229   42.871  1.000 28.282 0 266 ASP A CG  1 ? 
ATOM   1715 O OD1 . ASP A 1 231 ? -19.349 0.793   41.784  1.000 34.633 0 266 ASP A OD1 1 ? 
ATOM   1716 O OD2 . ASP A 1 231 ? -20.632 -0.191  43.245  1.000 34.715 0 266 ASP A OD2 1 ? 
ATOM   1717 N N   . ASP A 1 232 ? -14.993 -1.651  43.743  1.000 21.931 0 267 ASP A N   1 ? 
ATOM   1718 C CA  . ASP A 1 232 ? -13.829 -1.753  44.605  1.000 21.239 0 267 ASP A CA  1 ? 
ATOM   1719 C C   . ASP A 1 232 ? -12.753 -0.845  44.012  1.000 20.201 0 267 ASP A C   1 ? 
ATOM   1720 O O   . ASP A 1 232 ? -12.057 -1.197  43.067  1.000 20.835 0 267 ASP A O   1 ? 
ATOM   1721 C CB  . ASP A 1 232 ? -13.440 -3.205  44.899  1.000 20.934 0 267 ASP A CB  1 ? 
ATOM   1722 C CG  . ASP A 1 232 ? -12.359 -3.335  45.964  1.000 21.606 0 267 ASP A CG  1 ? 
ATOM   1723 O OD1 . ASP A 1 232 ? -11.613 -2.347  46.212  1.000 21.344 0 267 ASP A OD1 1 ? 
ATOM   1724 O OD2 . ASP A 1 232 ? -12.243 -4.412  46.545  1.000 21.342 0 267 ASP A OD2 1 ? 
ATOM   1725 N N   . THR A 1 233 ? -12.657 0.363   44.578  1.000 20.167 0 268 THR A N   1 ? 
ATOM   1726 C CA  . THR A 1 233 ? -11.909 1.469   44.004  1.000 20.551 0 268 THR A CA  1 ? 
ATOM   1727 C C   . THR A 1 233 ? -10.416 1.282   44.269  1.000 18.401 0 268 THR A C   1 ? 
ATOM   1728 O O   . THR A 1 233 ? -9.600  1.993   43.685  1.000 17.537 0 268 THR A O   1 ? 
ATOM   1729 C CB  . THR A 1 233 ? -12.452 2.807   44.544  1.000 20.828 0 268 THR A CB  1 ? 
ATOM   1730 O OG1 . THR A 1 233 ? -12.402 2.765   45.972  1.000 20.742 0 268 THR A OG1 1 ? 
ATOM   1731 C CG2 . THR A 1 233 ? -13.893 3.064   44.144  1.000 22.084 0 268 THR A CG2 1 ? 
ATOM   1732 N N   . ARG A 1 234 ? -10.055 0.315   45.121  1.000 17.449 0 269 ARG A N   1 ? 
ATOM   1733 C CA  . ARG A 1 234 ? -8.652  -0.024  45.321  1.000 18.982 0 269 ARG A CA  1 ? 
ATOM   1734 C C   . ARG A 1 234 ? -8.011  -0.627  44.066  1.000 18.821 0 269 ARG A C   1 ? 
ATOM   1735 O O   . ARG A 1 234 ? -6.782  -0.734  44.002  1.000 19.542 0 269 ARG A O   1 ? 
ATOM   1736 C CB  . ARG A 1 234 ? -8.512  -1.040  46.456  1.000 19.295 0 269 ARG A CB  1 ? 
ATOM   1737 C CG  . ARG A 1 234 ? -9.026  -0.539  47.795  1.000 19.715 0 269 ARG A CG  1 ? 
ATOM   1738 C CD  . ARG A 1 234 ? -8.957  -1.660  48.815  1.000 21.398 0 269 ARG A CD  1 ? 
ATOM   1739 N NE  . ARG A 1 234 ? -9.900  -2.753  48.571  1.000 21.162 0 269 ARG A NE  1 ? 
ATOM   1740 C CZ  . ARG A 1 234 ? -10.082 -3.789  49.385  1.000 20.613 0 269 ARG A CZ  1 ? 
ATOM   1741 N NH1 . ARG A 1 234 ? -9.299  -3.973  50.430  1.000 20.879 0 269 ARG A NH1 1 ? 
ATOM   1742 N NH2 . ARG A 1 234 ? -11.046 -4.652  49.138  1.000 21.116 0 269 ARG A NH2 1 ? 
ATOM   1743 N N   . TYR A 1 235 ? -8.825  -1.031  43.074  1.000 17.661 0 270 TYR A N   1 ? 
ATOM   1744 C CA  . TYR A 1 235 ? -8.298  -1.635  41.860  1.000 17.148 0 270 TYR A CA  1 ? 
ATOM   1745 C C   . TYR A 1 235 ? -8.025  -0.603  40.777  1.000 18.643 0 270 TYR A C   1 ? 
ATOM   1746 O O   . TYR A 1 235 ? -7.396  -0.934  39.770  1.000 17.628 0 270 TYR A O   1 ? 
ATOM   1747 C CB  . TYR A 1 235 ? -9.241  -2.727  41.366  1.000 16.145 0 270 TYR A CB  1 ? 
ATOM   1748 C CG  . TYR A 1 235 ? -9.222  -3.957  42.235  1.000 15.258 0 270 TYR A CG  1 ? 
ATOM   1749 C CD1 . TYR A 1 235 ? -9.908  -4.005  43.437  1.000 15.129 0 270 TYR A CD1 1 ? 
ATOM   1750 C CD2 . TYR A 1 235 ? -8.459  -5.052  41.886  1.000 14.077 0 270 TYR A CD2 1 ? 
ATOM   1751 C CE1 . TYR A 1 235 ? -9.910  -5.151  44.225  1.000 14.471 0 270 TYR A CE1 1 ? 
ATOM   1752 C CE2 . TYR A 1 235 ? -8.431  -6.189  42.675  1.000 14.582 0 270 TYR A CE2 1 ? 
ATOM   1753 C CZ  . TYR A 1 235 ? -9.173  -6.249  43.831  1.000 13.536 0 270 TYR A CZ  1 ? 
ATOM   1754 O OH  . TYR A 1 235 ? -9.128  -7.410  44.562  1.000 15.982 0 270 TYR A OH  1 ? 
ATOM   1755 N N   . ARG A 1 236 ? -8.470  0.647   40.990  1.000 20.369 0 271 ARG A N   1 ? 
ATOM   1756 C CA  . ARG A 1 236 ? -8.296  1.663   39.972  1.000 20.403 0 271 ARG A CA  1 ? 
ATOM   1757 C C   . ARG A 1 236 ? -6.812  1.865   39.657  1.000 19.995 0 271 ARG A C   1 ? 
ATOM   1758 O O   . ARG A 1 236 ? -6.432  2.150   38.517  1.000 17.511 0 271 ARG A O   1 ? 
ATOM   1759 C CB  . ARG A 1 236 ? -8.938  2.988   40.400  1.000 21.916 0 271 ARG A CB  1 ? 
ATOM   1760 C CG  . ARG A 1 236 ? -9.089  3.943   39.229  1.000 22.582 0 271 ARG A CG  1 ? 
ATOM   1761 C CD  . ARG A 1 236 ? -9.442  5.363   39.596  1.000 23.559 0 271 ARG A CD  1 ? 
ATOM   1762 N NE  . ARG A 1 236 ? -10.608 5.379   40.459  1.000 22.658 0 271 ARG A NE  1 ? 
ATOM   1763 C CZ  . ARG A 1 236 ? -11.866 5.208   40.087  1.000 23.443 0 271 ARG A CZ  1 ? 
ATOM   1764 N NH1 . ARG A 1 236 ? -12.215 4.998   38.828  1.000 24.663 0 271 ARG A NH1 1 ? 
ATOM   1765 N NH2 . ARG A 1 236 ? -12.785 5.265   41.019  1.000 24.525 0 271 ARG A NH2 1 ? 
ATOM   1766 N N   . LYS A 1 237 ? -5.977  1.770   40.690  1.000 19.541 0 272 LYS A N   1 ? 
ATOM   1767 C CA  . LYS A 1 237 ? -4.544  1.997   40.555  1.000 21.198 0 272 LYS A CA  1 ? 
ATOM   1768 C C   . LYS A 1 237 ? -3.890  1.069   39.522  1.000 20.402 0 272 LYS A C   1 ? 
ATOM   1769 O O   . LYS A 1 237 ? -2.862  1.430   38.971  1.000 20.758 0 272 LYS A O   1 ? 
ATOM   1770 C CB  . LYS A 1 237 ? -3.848  1.808   41.913  1.000 22.393 0 272 LYS A CB  1 ? 
ATOM   1771 C CG  . LYS A 1 237 ? -3.862  0.388   42.456  1.000 23.850 0 272 LYS A CG  1 ? 
ATOM   1772 C CD  . LYS A 1 237 ? -3.284  0.265   43.853  1.000 25.649 0 272 LYS A CD  1 ? 
ATOM   1773 C CE  . LYS A 1 237 ? -3.107  -1.186  44.237  1.000 27.129 0 272 LYS A CE  1 ? 
ATOM   1774 N NZ  . LYS A 1 237 ? -2.983  -1.361  45.703  1.000 31.256 0 272 LYS A NZ  1 ? 
ATOM   1775 N N   . PHE A 1 238 ? -4.434  -0.125  39.263  1.000 19.142 0 273 PHE A N   1 ? 
ATOM   1776 C CA  . PHE A 1 238 ? -3.837  -1.019  38.276  1.000 18.877 0 273 PHE A CA  1 ? 
ATOM   1777 C C   . PHE A 1 238 ? -4.150  -0.554  36.851  1.000 18.725 0 273 PHE A C   1 ? 
ATOM   1778 O O   . PHE A 1 238 ? -3.516  -0.995  35.889  1.000 20.516 0 273 PHE A O   1 ? 
ATOM   1779 C CB  . PHE A 1 238 ? -4.301  -2.459  38.508  1.000 20.399 0 273 PHE A CB  1 ? 
ATOM   1780 C CG  . PHE A 1 238 ? -3.993  -2.980  39.891  1.000 22.148 0 273 PHE A CG  1 ? 
ATOM   1781 C CD1 . PHE A 1 238 ? -2.689  -3.201  40.286  1.000 23.733 0 273 PHE A CD1 1 ? 
ATOM   1782 C CD2 . PHE A 1 238 ? -5.009  -3.211  40.816  1.000 21.119 0 273 PHE A CD2 1 ? 
ATOM   1783 C CE1 . PHE A 1 238 ? -2.404  -3.641  41.568  1.000 23.695 0 273 PHE A CE1 1 ? 
ATOM   1784 C CE2 . PHE A 1 238 ? -4.724  -3.666  42.092  1.000 20.941 0 273 PHE A CE2 1 ? 
ATOM   1785 C CZ  . PHE A 1 238 ? -3.423  -3.880  42.458  1.000 22.669 0 273 PHE A CZ  1 ? 
ATOM   1786 N N   . LEU A 1 239 ? -5.119  0.357   36.727  1.000 17.762 0 274 LEU A N   1 ? 
ATOM   1787 C CA  . LEU A 1 239 ? -5.658  0.806   35.452  1.000 18.762 0 274 LEU A CA  1 ? 
ATOM   1788 C C   . LEU A 1 239 ? -5.170  2.207   35.090  1.000 18.413 0 274 LEU A C   1 ? 
ATOM   1789 O O   . LEU A 1 239 ? -5.521  2.708   34.030  1.000 18.820 0 274 LEU A O   1 ? 
ATOM   1790 C CB  . LEU A 1 239 ? -7.187  0.779   35.584  1.000 18.215 0 274 LEU A CB  1 ? 
ATOM   1791 C CG  . LEU A 1 239 ? -7.797  -0.556  36.020  1.000 18.225 0 274 LEU A CG  1 ? 
ATOM   1792 C CD1 . LEU A 1 239 ? -9.294  -0.406  36.139  1.000 18.577 0 274 LEU A CD1 1 ? 
ATOM   1793 C CD2 . LEU A 1 239 ? -7.439  -1.679  35.043  1.000 19.427 0 274 LEU A CD2 1 ? 
ATOM   1794 N N   . CYS A 1 240 ? -4.360  2.809   35.975  1.000 20.139 0 275 CYS A N   1 ? 
ATOM   1795 C CA  . CYS A 1 240 ? -3.933  4.201   35.915  1.000 22.590 0 275 CYS A CA  1 ? 
ATOM   1796 C C   . CYS A 1 240 ? -2.405  4.264   35.917  1.000 23.808 0 275 CYS A C   1 ? 
ATOM   1797 O O   . CYS A 1 240 ? -1.759  3.440   36.561  1.000 24.275 0 275 CYS A O   1 ? 
ATOM   1798 C CB  . CYS A 1 240 ? -4.478  4.998   37.102  1.000 22.527 0 275 CYS A CB  1 ? 
ATOM   1799 S SG  . CYS A 1 240 ? -6.288  5.156   37.075  1.000 25.616 0 275 CYS A SG  1 ? 
ATOM   1800 N N   . ASN A 1 241 ? -1.843  5.230   35.186  1.000 27.226 0 276 ASN A N   1 ? 
ATOM   1801 C CA  . ASN A 1 241 ? -0.394  5.398   35.085  1.000 32.357 0 276 ASN A CA  1 ? 
ATOM   1802 C C   . ASN A 1 241 ? 0.247   4.081   34.677  1.000 29.770 0 276 ASN A C   1 ? 
ATOM   1803 O O   . ASN A 1 241 ? 1.234   3.670   35.267  1.000 29.169 0 276 ASN A O   1 ? 
ATOM   1804 C CB  . ASN A 1 241 ? 0.241   5.834   36.408  1.000 33.841 0 276 ASN A CB  1 ? 
ATOM   1805 C CG  . ASN A 1 241 ? -0.458  7.028   37.008  1.000 38.425 0 276 ASN A CG  1 ? 
ATOM   1806 O OD1 . ASN A 1 241 ? -0.505  8.072   36.360  1.000 38.090 0 276 ASN A OD1 1 ? 
ATOM   1807 N ND2 . ASN A 1 241 ? -1.008  6.873   38.208  1.000 38.644 0 276 ASN A ND2 1 ? 
ATOM   1808 N N   . VAL A 1 242 ? -0.341  3.418   33.682  1.000 30.571 0 277 VAL A N   1 ? 
ATOM   1809 C CA  . VAL A 1 242 ? 0.042   2.059   33.358  1.000 31.766 0 277 VAL A CA  1 ? 
ATOM   1810 C C   . VAL A 1 242 ? 1.392   2.084   32.645  1.000 34.723 0 277 VAL A C   1 ? 
ATOM   1811 O O   . VAL A 1 242 ? 1.540   2.704   31.591  1.000 36.063 0 277 VAL A O   1 ? 
ATOM   1812 C CB  . VAL A 1 242 ? -1.056  1.356   32.536  1.000 31.194 0 277 VAL A CB  1 ? 
ATOM   1813 C CG1 . VAL A 1 242 ? -0.570  0.025   31.972  1.000 31.019 0 277 VAL A CG1 1 ? 
ATOM   1814 C CG2 . VAL A 1 242 ? -2.318  1.183   33.390  1.000 29.873 0 277 VAL A CG2 1 ? 
ATOM   1815 N N   . ASN A 1 243 ? 2.370   1.400   33.243  1.000 32.187 0 278 ASN A N   1 ? 
ATOM   1816 C CA  . ASN A 1 243 ? 3.665   1.294   32.615  1.000 37.173 0 278 ASN A CA  1 ? 
ATOM   1817 C C   . ASN A 1 243 ? 4.051   -0.177  32.612  1.000 35.298 0 278 ASN A C   1 ? 
ATOM   1818 O O   . ASN A 1 243 ? 4.713   -0.663  33.522  1.000 42.533 0 278 ASN A O   1 ? 
ATOM   1819 C CB  . ASN A 1 243 ? 4.694   2.210   33.269  1.000 43.232 0 278 ASN A CB  1 ? 
ATOM   1820 C CG  . ASN A 1 243 ? 5.717   2.617   32.237  1.000 52.353 0 278 ASN A CG  1 ? 
ATOM   1821 O OD1 . ASN A 1 243 ? 5.682   3.752   31.767  1.000 68.598 0 278 ASN A OD1 1 ? 
ATOM   1822 N ND2 . ASN A 1 243 ? 6.540   1.672   31.797  1.000 55.798 0 278 ASN A ND2 1 ? 
ATOM   1823 N N   . ASP A 1 244 ? 3.567   -0.883  31.589  1.000 29.398 0 279 ASP A N   1 ? 
ATOM   1824 C CA  . ASP A 1 244 ? 3.558   -2.325  31.617  1.000 28.195 0 279 ASP A CA  1 ? 
ATOM   1825 C C   . ASP A 1 244 ? 4.249   -2.812  30.354  1.000 28.329 0 279 ASP A C   1 ? 
ATOM   1826 O O   . ASP A 1 244 ? 3.717   -2.656  29.239  1.000 25.010 0 279 ASP A O   1 ? 
ATOM   1827 C CB  . ASP A 1 244 ? 2.133   -2.851  31.758  1.000 28.317 0 279 ASP A CB  1 ? 
ATOM   1828 C CG  . ASP A 1 244 ? 2.043   -4.357  31.777  1.000 28.239 0 279 ASP A CG  1 ? 
ATOM   1829 O OD1 . ASP A 1 244 ? 3.107   -5.003  31.624  1.000 25.400 0 279 ASP A OD1 1 ? 
ATOM   1830 O OD2 . ASP A 1 244 ? 0.902   -4.859  31.923  1.000 28.551 0 279 ASP A OD2 1 ? 
ATOM   1831 N N   . PRO A 1 245 ? 5.454   -3.414  30.494  1.000 28.066 0 280 PRO A N   1 ? 
ATOM   1832 C CA  . PRO A 1 245 ? 6.201   -3.896  29.329  1.000 30.012 0 280 PRO A CA  1 ? 
ATOM   1833 C C   . PRO A 1 245 ? 5.542   -5.071  28.598  1.000 29.366 0 280 PRO A C   1 ? 
ATOM   1834 O O   . PRO A 1 245 ? 5.899   -5.333  27.458  1.000 36.111 0 280 PRO A O   1 ? 
ATOM   1835 C CB  . PRO A 1 245 ? 7.563   -4.293  29.911  1.000 30.817 0 280 PRO A CB  1 ? 
ATOM   1836 C CG  . PRO A 1 245 ? 7.247   -4.613  31.362  1.000 32.651 0 280 PRO A CG  1 ? 
ATOM   1837 C CD  . PRO A 1 245 ? 6.189   -3.597  31.754  1.000 30.981 0 280 PRO A CD  1 ? 
ATOM   1838 N N   . ALA A 1 246 ? 4.556   -5.740  29.216  1.000 27.466 0 281 ALA A N   1 ? 
ATOM   1839 C CA  . ALA A 1 246 ? 3.752   -6.750  28.529  1.000 25.213 0 281 ALA A CA  1 ? 
ATOM   1840 C C   . ALA A 1 246 ? 2.816   -6.123  27.489  1.000 23.460 0 281 ALA A C   1 ? 
ATOM   1841 O O   . ALA A 1 246 ? 2.308   -6.834  26.628  1.000 20.836 0 281 ALA A O   1 ? 
ATOM   1842 C CB  . ALA A 1 246 ? 2.971   -7.569  29.529  1.000 24.862 0 281 ALA A CB  1 ? 
ATOM   1843 N N   . LEU A 1 247 ? 2.591   -4.806  27.563  1.000 22.602 0 282 LEU A N   1 ? 
ATOM   1844 C CA  . LEU A 1 247 ? 1.716   -4.105  26.634  1.000 23.015 0 282 LEU A CA  1 ? 
ATOM   1845 C C   . LEU A 1 247 ? 2.547   -3.293  25.649  1.000 22.723 0 282 LEU A C   1 ? 
ATOM   1846 O O   . LEU A 1 247 ? 3.496   -2.619  26.052  1.000 21.561 0 282 LEU A O   1 ? 
ATOM   1847 C CB  . LEU A 1 247 ? 0.781   -3.145  27.383  1.000 23.351 0 282 LEU A CB  1 ? 
ATOM   1848 C CG  . LEU A 1 247 ? -0.116  -3.736  28.471  1.000 23.723 0 282 LEU A CG  1 ? 
ATOM   1849 C CD1 . LEU A 1 247 ? -1.084  -2.660  28.991  1.000 24.392 0 282 LEU A CD1 1 ? 
ATOM   1850 C CD2 . LEU A 1 247 ? -0.888  -4.937  27.961  1.000 23.477 0 282 LEU A CD2 1 ? 
ATOM   1851 N N   . CYS A 1 248 ? 2.128   -3.303  24.379  1.000 22.500 0 283 CYS A N   1 ? 
ATOM   1852 C CA  A CYS A 1 248 ? 2.798   -2.531  23.347  0.500 22.833 0 283 CYS A CA  1 ? 
ATOM   1853 C CA  B CYS A 1 248 ? 2.797   -2.535  23.339  0.500 24.134 0 283 CYS A CA  1 ? 
ATOM   1854 C C   . CYS A 1 248 ? 1.937   -1.355  22.888  1.000 22.744 0 283 CYS A C   1 ? 
ATOM   1855 O O   . CYS A 1 248 ? 2.358   -0.571  22.044  1.000 23.883 0 283 CYS A O   1 ? 
ATOM   1856 C CB  A CYS A 1 248 ? 3.196   -3.436  22.189  0.500 23.336 0 283 CYS A CB  1 ? 
ATOM   1857 C CB  B CYS A 1 248 ? 3.159   -3.423  22.153  0.500 25.883 0 283 CYS A CB  1 ? 
ATOM   1858 S SG  A CYS A 1 248 ? 4.784   -4.264  22.471  0.500 22.544 0 283 CYS A SG  1 ? 
ATOM   1859 S SG  B CYS A 1 248 ? 1.764   -4.375  21.500  0.500 30.487 0 283 CYS A SG  1 ? 
ATOM   1860 N N   . ASP A 1 249 ? 0.727   -1.235  23.439  1.000 21.438 0 284 ASP A N   1 ? 
ATOM   1861 C CA  . ASP A 1 249 ? -0.070  -0.029  23.269  1.000 20.988 0 284 ASP A CA  1 ? 
ATOM   1862 C C   . ASP A 1 249 ? -1.053  0.011   24.425  1.000 20.820 0 284 ASP A C   1 ? 
ATOM   1863 O O   . ASP A 1 249 ? -1.432  -1.027  24.959  1.000 19.827 0 284 ASP A O   1 ? 
ATOM   1864 C CB  . ASP A 1 249 ? -0.750  0.059   21.898  1.000 20.743 0 284 ASP A CB  1 ? 
ATOM   1865 C CG  . ASP A 1 249 ? -1.060  1.481   21.433  1.000 21.353 0 284 ASP A CG  1 ? 
ATOM   1866 O OD1 . ASP A 1 249 ? -0.826  2.444   22.212  1.000 21.473 0 284 ASP A OD1 1 ? 
ATOM   1867 O OD2 . ASP A 1 249 ? -1.515  1.627   20.276  1.000 20.239 0 284 ASP A OD2 1 ? 
ATOM   1868 N N   . PHE A 1 250 ? -1.427  1.225   24.824  1.000 21.739 0 285 PHE A N   1 ? 
ATOM   1869 C CA  . PHE A 1 250 ? -2.365  1.427   25.907  1.000 20.590 0 285 PHE A CA  1 ? 
ATOM   1870 C C   . PHE A 1 250 ? -3.003  2.798   25.719  1.000 21.073 0 285 PHE A C   1 ? 
ATOM   1871 O O   . PHE A 1 250 ? -2.294  3.779   25.527  1.000 18.652 0 285 PHE A O   1 ? 
ATOM   1872 C CB  . PHE A 1 250 ? -1.674  1.285   27.265  1.000 21.701 0 285 PHE A CB  1 ? 
ATOM   1873 C CG  . PHE A 1 250 ? -2.605  1.488   28.432  1.000 21.578 0 285 PHE A CG  1 ? 
ATOM   1874 C CD1 . PHE A 1 250 ? -2.911  2.761   28.886  1.000 21.450 0 285 PHE A CD1 1 ? 
ATOM   1875 C CD2 . PHE A 1 250 ? -3.231  0.399   29.024  1.000 21.500 0 285 PHE A CD2 1 ? 
ATOM   1876 C CE1 . PHE A 1 250 ? -3.814  2.933   29.926  1.000 21.641 0 285 PHE A CE1 1 ? 
ATOM   1877 C CE2 . PHE A 1 250 ? -4.139  0.574   30.055  1.000 22.331 0 285 PHE A CE2 1 ? 
ATOM   1878 C CZ  . PHE A 1 250 ? -4.419  1.842   30.513  1.000 21.620 0 285 PHE A CZ  1 ? 
ATOM   1879 N N   . LYS A 1 251 ? -4.340  2.842   25.713  1.000 19.936 0 286 LYS A N   1 ? 
ATOM   1880 C CA  . LYS A 1 251 ? -5.090  4.090   25.739  1.000 19.776 0 286 LYS A CA  1 ? 
ATOM   1881 C C   . LYS A 1 251 ? -6.218  3.902   26.745  1.000 20.456 0 286 LYS A C   1 ? 
ATOM   1882 O O   . LYS A 1 251 ? -6.725  2.793   26.940  1.000 17.883 0 286 LYS A O   1 ? 
ATOM   1883 C CB  . LYS A 1 251 ? -5.682  4.467   24.374  1.000 21.239 0 286 LYS A CB  1 ? 
ATOM   1884 C CG  . LYS A 1 251 ? -4.732  4.440   23.180  1.000 21.859 0 286 LYS A CG  1 ? 
ATOM   1885 C CD  . LYS A 1 251 ? -5.433  4.637   21.862  1.000 23.691 0 286 LYS A CD  1 ? 
ATOM   1886 C CE  . LYS A 1 251 ? -4.551  4.423   20.648  1.000 26.510 0 286 LYS A CE  1 ? 
ATOM   1887 N NZ  . LYS A 1 251 ? -3.482  5.451   20.555  1.000 28.390 0 286 LYS A NZ  1 ? 
ATOM   1888 N N   . SER A 1 252 ? -6.609  5.001   27.396  1.000 20.632 0 287 SER A N   1 ? 
ATOM   1889 C CA  . SER A 1 252 ? -7.773  4.966   28.266  1.000 21.189 0 287 SER A CA  1 ? 
ATOM   1890 C C   . SER A 1 252 ? -8.446  6.332   28.255  1.000 20.560 0 287 SER A C   1 ? 
ATOM   1891 O O   . SER A 1 252 ? -7.793  7.324   27.955  1.000 18.037 0 287 SER A O   1 ? 
ATOM   1892 C CB  . SER A 1 252 ? -7.394  4.562   29.664  1.000 20.385 0 287 SER A CB  1 ? 
ATOM   1893 O OG  . SER A 1 252 ? -6.766  5.651   30.324  1.000 19.735 0 287 SER A OG  1 ? 
ATOM   1894 N N   . ASN A 1 253 ? -9.729  6.323   28.618  1.000 20.148 0 288 ASN A N   1 ? 
ATOM   1895 C CA  . ASN A 1 253 ? -10.539 7.515   28.853  1.000 20.333 0 288 ASN A CA  1 ? 
ATOM   1896 C C   . ASN A 1 253 ? -11.551 7.230   29.965  1.000 19.007 0 288 ASN A C   1 ? 
ATOM   1897 O O   . ASN A 1 253 ? -12.041 6.099   30.062  1.000 18.061 0 288 ASN A O   1 ? 
ATOM   1898 C CB  . ASN A 1 253 ? -11.257 7.956   27.579  1.000 21.449 0 288 ASN A CB  1 ? 
ATOM   1899 C CG  . ASN A 1 253 ? -10.276 8.513   26.570  1.000 24.842 0 288 ASN A CG  1 ? 
ATOM   1900 O OD1 . ASN A 1 253 ? -9.863  9.669   26.697  1.000 28.684 0 288 ASN A OD1 1 ? 
ATOM   1901 N ND2 . ASN A 1 253 ? -9.875  7.706   25.597  1.000 21.869 0 288 ASN A ND2 1 ? 
ATOM   1902 N N   . ASN A 1 254 ? -11.788 8.232   30.827  1.000 16.396 0 289 ASN A N   1 ? 
ATOM   1903 C CA  . ASN A 1 254 ? -12.868 8.251   31.802  1.000 17.332 0 289 ASN A CA  1 ? 
ATOM   1904 C C   . ASN A 1 254 ? -12.688 7.169   32.870  1.000 17.698 0 289 ASN A C   1 ? 
ATOM   1905 O O   . ASN A 1 254 ? -13.674 6.644   33.400  1.000 16.302 0 289 ASN A O   1 ? 
ATOM   1906 C CB  . ASN A 1 254 ? -14.247 8.109   31.147  1.000 18.304 0 289 ASN A CB  1 ? 
ATOM   1907 C CG  . ASN A 1 254 ? -14.466 9.079   29.998  1.000 19.950 0 289 ASN A CG  1 ? 
ATOM   1908 O OD1 . ASN A 1 254 ? -14.403 10.278  30.216  1.000 20.967 0 289 ASN A OD1 1 ? 
ATOM   1909 N ND2 . ASN A 1 254 ? -14.713 8.591   28.790  1.000 19.813 0 289 ASN A ND2 1 ? 
ATOM   1910 N N   . LEU A 1 255 ? -11.432 6.911   33.260  1.000 18.282 0 290 LEU A N   1 ? 
ATOM   1911 C CA  . LEU A 1 255 ? -11.165 6.035   34.396  1.000 20.003 0 290 LEU A CA  1 ? 
ATOM   1912 C C   . LEU A 1 255 ? -11.120 6.818   35.713  1.000 20.212 0 290 LEU A C   1 ? 
ATOM   1913 O O   . LEU A 1 255 ? -11.105 6.201   36.777  1.000 22.422 0 290 LEU A O   1 ? 
ATOM   1914 C CB  . LEU A 1 255 ? -9.843  5.302   34.182  1.000 20.621 0 290 LEU A CB  1 ? 
ATOM   1915 C CG  . LEU A 1 255 ? -9.757  4.398   32.954  1.000 22.377 0 290 LEU A CG  1 ? 
ATOM   1916 C CD1 . LEU A 1 255 ? -8.560  3.486   33.093  1.000 24.628 0 290 LEU A CD1 1 ? 
ATOM   1917 C CD2 . LEU A 1 255 ? -11.027 3.600   32.728  1.000 22.024 0 290 LEU A CD2 1 ? 
ATOM   1918 N N   . PHE A 1 256 ? -11.116 8.159   35.632  1.000 19.602 0 291 PHE A N   1 ? 
ATOM   1919 C CA  . PHE A 1 256 ? -11.112 9.028   36.804  1.000 19.048 0 291 PHE A CA  1 ? 
ATOM   1920 C C   . PHE A 1 256 ? -9.906  8.708   37.681  1.000 19.511 0 291 PHE A C   1 ? 
ATOM   1921 O O   . PHE A 1 256 ? -10.012 8.620   38.901  1.000 20.546 0 291 PHE A O   1 ? 
ATOM   1922 C CB  . PHE A 1 256 ? -12.469 8.942   37.506  1.000 18.858 0 291 PHE A CB  1 ? 
ATOM   1923 C CG  . PHE A 1 256 ? -13.584 9.647   36.772  1.000 19.068 0 291 PHE A CG  1 ? 
ATOM   1924 C CD1 . PHE A 1 256 ? -14.139 9.121   35.609  1.000 18.934 0 291 PHE A CD1 1 ? 
ATOM   1925 C CD2 . PHE A 1 256 ? -14.068 10.860  37.238  1.000 19.242 0 291 PHE A CD2 1 ? 
ATOM   1926 C CE1 . PHE A 1 256 ? -15.167 9.780   34.951  1.000 20.107 0 291 PHE A CE1 1 ? 
ATOM   1927 C CE2 . PHE A 1 256 ? -15.097 11.520  36.582  1.000 18.810 0 291 PHE A CE2 1 ? 
ATOM   1928 C CZ  . PHE A 1 256 ? -15.641 10.987  35.433  1.000 19.319 0 291 PHE A CZ  1 ? 
ATOM   1929 N N   . CYS A 1 257 ? -8.752  8.498   37.041  1.000 21.124 0 292 CYS A N   1 ? 
ATOM   1930 C CA  . CYS A 1 257 ? -7.483  8.380   37.748  1.000 25.248 0 292 CYS A CA  1 ? 
ATOM   1931 C C   . CYS A 1 257 ? -7.212  9.664   38.534  1.000 28.130 0 292 CYS A C   1 ? 
ATOM   1932 O O   . CYS A 1 257 ? -7.430  10.757  38.011  1.000 28.868 0 292 CYS A O   1 ? 
ATOM   1933 C CB  . CYS A 1 257 ? -6.346  8.125   36.761  1.000 24.790 0 292 CYS A CB  1 ? 
ATOM   1934 S SG  . CYS A 1 257 ? -6.605  6.629   35.757  1.000 25.749 0 292 CYS A SG  1 ? 
ATOM   1935 N N   . SER A 1 258 ? -6.742  9.533   39.781  1.000 32.139 0 293 SER A N   1 ? 
ATOM   1936 C CA  . SER A 1 258 ? -6.330  10.694  40.568  1.000 38.707 0 293 SER A CA  1 ? 
ATOM   1937 C C   . SER A 1 258 ? -4.827  10.901  40.417  1.000 41.014 0 293 SER A C   1 ? 
ATOM   1938 O O   . SER A 1 258 ? -4.140  10.031  40.963  1.000 42.391 0 293 SER A O   1 ? 
ATOM   1939 C CB  . SER A 1 258 ? -6.658  10.539  42.025  1.000 39.920 0 293 SER A CB  1 ? 
ATOM   1940 O OG  . SER A 1 258 ? -8.042  10.667  42.238  1.000 40.013 0 293 SER A OG  1 ? 
ATOM   1941 N N   . LEU B 1 5   ? -9.360  -55.717 9.700   1.000 55.491 0 40  LEU B N   1 ? 
ATOM   1942 C CA  . LEU B 1 5   ? -10.765 -56.120 9.426   1.000 53.517 0 40  LEU B CA  1 ? 
ATOM   1943 C C   . LEU B 1 5   ? -11.447 -56.472 10.751  1.000 57.008 0 40  LEU B C   1 ? 
ATOM   1944 O O   . LEU B 1 5   ? -11.538 -57.641 11.127  1.000 61.479 0 40  LEU B O   1 ? 
ATOM   1945 C CB  . LEU B 1 5   ? -10.751 -57.301 8.443   1.000 50.238 0 40  LEU B CB  1 ? 
ATOM   1946 C CG  . LEU B 1 5   ? -11.916 -57.366 7.451   1.000 51.551 0 40  LEU B CG  1 ? 
ATOM   1947 C CD1 . LEU B 1 5   ? -11.484 -56.862 6.076   1.000 47.328 0 40  LEU B CD1 1 ? 
ATOM   1948 C CD2 . LEU B 1 5   ? -12.504 -58.775 7.353   1.000 52.635 0 40  LEU B CD2 1 ? 
ATOM   1949 N N   . VAL B 1 6   ? -11.928 -55.437 11.452  1.000 61.756 0 41  VAL B N   1 ? 
ATOM   1950 C CA  . VAL B 1 6   ? -12.598 -55.598 12.737  1.000 63.207 0 41  VAL B CA  1 ? 
ATOM   1951 C C   . VAL B 1 6   ? -14.056 -55.151 12.585  1.000 64.805 0 41  VAL B C   1 ? 
ATOM   1952 O O   . VAL B 1 6   ? -14.377 -54.310 11.747  1.000 67.252 0 41  VAL B O   1 ? 
ATOM   1953 C CB  . VAL B 1 6   ? -11.861 -54.877 13.899  1.000 59.456 0 41  VAL B CB  1 ? 
ATOM   1954 C CG1 . VAL B 1 6   ? -10.403 -55.310 14.017  1.000 58.215 0 41  VAL B CG1 1 ? 
ATOM   1955 C CG2 . VAL B 1 6   ? -11.941 -53.357 13.840  1.000 56.521 0 41  VAL B CG2 1 ? 
ATOM   1956 N N   . GLY B 1 7   ? -14.940 -55.741 13.398  1.000 64.145 0 42  GLY B N   1 ? 
ATOM   1957 C CA  . GLY B 1 7   ? -16.368 -55.464 13.340  1.000 64.170 0 42  GLY B CA  1 ? 
ATOM   1958 C C   . GLY B 1 7   ? -17.099 -56.411 12.388  1.000 62.931 0 42  GLY B C   1 ? 
ATOM   1959 O O   . GLY B 1 7   ? -16.482 -57.049 11.527  1.000 62.962 0 42  GLY B O   1 ? 
ATOM   1960 N N   . PRO B 1 8   ? -18.440 -56.553 12.535  1.000 59.522 0 43  PRO B N   1 ? 
ATOM   1961 C CA  . PRO B 1 8   ? -19.256 -57.306 11.571  1.000 55.423 0 43  PRO B CA  1 ? 
ATOM   1962 C C   . PRO B 1 8   ? -19.505 -56.454 10.320  1.000 50.892 0 43  PRO B C   1 ? 
ATOM   1963 O O   . PRO B 1 8   ? -18.837 -55.441 10.119  1.000 48.671 0 43  PRO B O   1 ? 
ATOM   1964 C CB  . PRO B 1 8   ? -20.526 -57.621 12.373  1.000 53.715 0 43  PRO B CB  1 ? 
ATOM   1965 C CG  . PRO B 1 8   ? -20.646 -56.446 13.331  1.000 57.651 0 43  PRO B CG  1 ? 
ATOM   1966 C CD  . PRO B 1 8   ? -19.233 -55.983 13.637  1.000 59.532 0 43  PRO B CD  1 ? 
ATOM   1967 N N   . GLU B 1 9   ? -20.438 -56.865 9.456   1.000 44.685 0 44  GLU B N   1 ? 
ATOM   1968 C CA  . GLU B 1 9   ? -20.731 -56.087 8.263   1.000 42.743 0 44  GLU B CA  1 ? 
ATOM   1969 C C   . GLU B 1 9   ? -21.203 -54.688 8.666   1.000 37.656 0 44  GLU B C   1 ? 
ATOM   1970 O O   . GLU B 1 9   ? -22.150 -54.551 9.440   1.000 37.461 0 44  GLU B O   1 ? 
ATOM   1971 C CB  . GLU B 1 9   ? -21.804 -56.764 7.405   1.000 45.229 0 44  GLU B CB  1 ? 
ATOM   1972 C CG  . GLU B 1 9   ? -21.886 -56.196 6.000   1.000 45.692 0 44  GLU B CG  1 ? 
ATOM   1973 C CD  . GLU B 1 9   ? -20.634 -56.441 5.168   1.000 49.896 0 44  GLU B CD  1 ? 
ATOM   1974 O OE1 . GLU B 1 9   ? -19.811 -57.277 5.583   1.000 48.352 0 44  GLU B OE1 1 ? 
ATOM   1975 O OE2 . GLU B 1 9   ? -20.453 -55.754 4.146   1.000 53.172 0 44  GLU B OE2 1 ? 
ATOM   1976 N N   . PRO B 1 10  ? -20.571 -53.597 8.172   1.000 30.362 0 45  PRO B N   1 ? 
ATOM   1977 C CA  . PRO B 1 10  ? -21.036 -52.260 8.509   1.000 28.744 0 45  PRO B CA  1 ? 
ATOM   1978 C C   . PRO B 1 10  ? -22.367 -51.947 7.839   1.000 27.995 0 45  PRO B C   1 ? 
ATOM   1979 O O   . PRO B 1 10  ? -22.605 -52.365 6.706   1.000 26.911 0 45  PRO B O   1 ? 
ATOM   1980 C CB  . PRO B 1 10  ? -19.939 -51.350 7.954   1.000 28.781 0 45  PRO B CB  1 ? 
ATOM   1981 C CG  . PRO B 1 10  ? -19.362 -52.145 6.808   1.000 28.067 0 45  PRO B CG  1 ? 
ATOM   1982 C CD  . PRO B 1 10  ? -19.396 -53.577 7.295   1.000 28.572 0 45  PRO B CD  1 ? 
ATOM   1983 N N   . THR B 1 11  ? -23.199 -51.167 8.539   1.000 28.240 0 46  THR B N   1 ? 
ATOM   1984 C CA  . THR B 1 11  ? -24.431 -50.641 7.978   1.000 26.917 0 46  THR B CA  1 ? 
ATOM   1985 C C   . THR B 1 11  ? -24.467 -49.133 8.196   1.000 27.204 0 46  THR B C   1 ? 
ATOM   1986 O O   . THR B 1 11  ? -23.738 -48.585 9.032   1.000 28.098 0 46  THR B O   1 ? 
ATOM   1987 C CB  . THR B 1 11  ? -25.645 -51.316 8.641   1.000 28.034 0 46  THR B CB  1 ? 
ATOM   1988 O OG1 . THR B 1 11  ? -25.764 -50.816 9.970   1.000 25.248 0 46  THR B OG1 1 ? 
ATOM   1989 C CG2 . THR B 1 11  ? -25.536 -52.823 8.702   1.000 25.593 0 46  THR B CG2 1 ? 
ATOM   1990 N N   . LEU B 1 12  ? -25.381 -48.477 7.488   1.000 27.126 0 47  LEU B N   1 ? 
ATOM   1991 C CA  . LEU B 1 12  ? -25.605 -47.053 7.659   1.000 28.314 0 47  LEU B CA  1 ? 
ATOM   1992 C C   . LEU B 1 12  ? -25.868 -46.735 9.136   1.000 28.719 0 47  LEU B C   1 ? 
ATOM   1993 O O   . LEU B 1 12  ? -25.351 -45.750 9.684   1.000 25.013 0 47  LEU B O   1 ? 
ATOM   1994 C CB  . LEU B 1 12  ? -26.788 -46.688 6.759   1.000 31.301 0 47  LEU B CB  1 ? 
ATOM   1995 C CG  . LEU B 1 12  ? -26.814 -45.280 6.190   1.000 34.645 0 47  LEU B CG  1 ? 
ATOM   1996 C CD1 . LEU B 1 12  ? -25.476 -44.908 5.527   1.000 33.022 0 47  LEU B CD1 1 ? 
ATOM   1997 C CD2 . LEU B 1 12  ? -27.965 -45.182 5.196   1.000 35.648 0 47  LEU B CD2 1 ? 
ATOM   1998 N N   . GLU B 1 13  ? -26.670 -47.595 9.773   1.000 28.193 0 48  GLU B N   1 ? 
ATOM   1999 C CA  . GLU B 1 13  ? -27.072 -47.434 11.158  1.000 31.319 0 48  GLU B CA  1 ? 
ATOM   2000 C C   . GLU B 1 13  ? -25.865 -47.599 12.083  1.000 26.391 0 48  GLU B C   1 ? 
ATOM   2001 O O   . GLU B 1 13  ? -25.725 -46.844 13.041  1.000 26.211 0 48  GLU B O   1 ? 
ATOM   2002 C CB  . GLU B 1 13  ? -28.153 -48.459 11.535  1.000 36.306 0 48  GLU B CB  1 ? 
ATOM   2003 C CG  . GLU B 1 13  ? -29.433 -48.428 10.685  1.000 43.783 0 48  GLU B CG  1 ? 
ATOM   2004 C CD  . GLU B 1 13  ? -29.338 -48.497 9.161   1.000 51.545 0 48  GLU B CD  1 ? 
ATOM   2005 O OE1 . GLU B 1 13  ? -28.742 -49.459 8.614   1.000 49.059 0 48  GLU B OE1 1 ? 
ATOM   2006 O OE2 . GLU B 1 13  ? -29.898 -47.585 8.499   1.000 63.253 0 48  GLU B OE2 1 ? 
ATOM   2007 N N   . SER B 1 14  ? -24.992 -48.581 11.796  1.000 24.474 0 49  SER B N   1 ? 
ATOM   2008 C CA  . SER B 1 14  ? -23.881 -48.905 12.687  1.000 23.652 0 49  SER B CA  1 ? 
ATOM   2009 C C   . SER B 1 14  ? -22.811 -47.808 12.694  1.000 23.573 0 49  SER B C   1 ? 
ATOM   2010 O O   . SER B 1 14  ? -22.147 -47.611 13.716  1.000 23.785 0 49  SER B O   1 ? 
ATOM   2011 C CB  . SER B 1 14  ? -23.283 -50.266 12.377  1.000 23.102 0 49  SER B CB  1 ? 
ATOM   2012 O OG  . SER B 1 14  ? -22.479 -50.230 11.213  1.000 23.408 0 49  SER B OG  1 ? 
ATOM   2013 N N   . LEU B 1 15  ? -22.648 -47.108 11.560  1.000 23.043 0 50  LEU B N   1 ? 
ATOM   2014 C CA  . LEU B 1 15  ? -21.675 -46.028 11.411  1.000 22.137 0 50  LEU B CA  1 ? 
ATOM   2015 C C   . LEU B 1 15  ? -22.057 -44.839 12.285  1.000 22.074 0 50  LEU B C   1 ? 
ATOM   2016 O O   . LEU B 1 15  ? -21.186 -44.062 12.661  1.000 25.600 0 50  LEU B O   1 ? 
ATOM   2017 C CB  . LEU B 1 15  ? -21.618 -45.561 9.951   1.000 22.700 0 50  LEU B CB  1 ? 
ATOM   2018 C CG  . LEU B 1 15  ? -21.094 -46.559 8.914   1.000 24.071 0 50  LEU B CG  1 ? 
ATOM   2019 C CD1 . LEU B 1 15  ? -21.131 -45.961 7.517   1.000 24.877 0 50  LEU B CD1 1 ? 
ATOM   2020 C CD2 . LEU B 1 15  ? -19.683 -47.007 9.252   1.000 24.473 0 50  LEU B CD2 1 ? 
ATOM   2021 N N   . GLN B 1 16  ? -23.355 -44.666 12.546  1.000 20.032 0 51  GLN B N   1 ? 
ATOM   2022 C CA  . GLN B 1 16  ? -23.844 -43.510 13.278  1.000 23.269 0 51  GLN B CA  1 ? 
ATOM   2023 C C   . GLN B 1 16  ? -23.875 -43.758 14.785  1.000 23.445 0 51  GLN B C   1 ? 
ATOM   2024 O O   . GLN B 1 16  ? -24.143 -42.840 15.551  1.000 24.752 0 51  GLN B O   1 ? 
ATOM   2025 C CB  . GLN B 1 16  ? -25.236 -43.133 12.779  1.000 22.865 0 51  GLN B CB  1 ? 
ATOM   2026 C CG  . GLN B 1 16  ? -25.230 -42.610 11.348  1.000 23.447 0 51  GLN B CG  1 ? 
ATOM   2027 C CD  . GLN B 1 16  ? -26.637 -42.480 10.805  1.000 23.704 0 51  GLN B CD  1 ? 
ATOM   2028 O OE1 . GLN B 1 16  ? -27.408 -41.616 11.204  1.000 23.630 0 51  GLN B OE1 1 ? 
ATOM   2029 N NE2 . GLN B 1 16  ? -26.998 -43.371 9.898   1.000 24.596 0 51  GLN B NE2 1 ? 
ATOM   2030 N N   . LYS B 1 17  ? -23.655 -44.992 15.224  1.000 23.544 0 52  LYS B N   1 ? 
ATOM   2031 C CA  . LYS B 1 17  ? -23.592 -45.265 16.654  1.000 25.271 0 52  LYS B CA  1 ? 
ATOM   2032 C C   . LYS B 1 17  ? -22.149 -45.562 17.029  1.000 23.157 0 52  LYS B C   1 ? 
ATOM   2033 O O   . LYS B 1 17  ? -21.331 -45.837 16.154  1.000 19.952 0 52  LYS B O   1 ? 
ATOM   2034 C CB  . LYS B 1 17  ? -24.459 -46.482 17.002  1.000 30.651 0 52  LYS B CB  1 ? 
ATOM   2035 C CG  . LYS B 1 17  ? -25.930 -46.313 16.663  1.000 33.503 0 52  LYS B CG  1 ? 
ATOM   2036 C CD  . LYS B 1 17  ? -26.665 -47.604 16.483  1.000 41.910 0 52  LYS B CD  1 ? 
ATOM   2037 C CE  . LYS B 1 17  ? -26.719 -48.413 17.755  1.000 47.039 0 52  LYS B CE  1 ? 
ATOM   2038 N NZ  . LYS B 1 17  ? -27.003 -49.831 17.442  1.000 54.327 0 52  LYS B NZ  1 ? 
ATOM   2039 N N   . LEU B 1 18  ? -21.876 -45.564 18.333  1.000 20.988 0 53  LEU B N   1 ? 
ATOM   2040 C CA  . LEU B 1 18  ? -20.605 -46.047 18.833  1.000 22.803 0 53  LEU B CA  1 ? 
ATOM   2041 C C   . LEU B 1 18  ? -20.354 -47.430 18.232  1.000 21.871 0 53  LEU B C   1 ? 
ATOM   2042 O O   . LEU B 1 18  ? -21.280 -48.223 18.071  1.000 20.077 0 53  LEU B O   1 ? 
ATOM   2043 C CB  . LEU B 1 18  ? -20.602 -46.044 20.372  1.000 22.841 0 53  LEU B CB  1 ? 
ATOM   2044 C CG  . LEU B 1 18  ? -20.679 -44.663 21.032  1.000 24.321 0 53  LEU B CG  1 ? 
ATOM   2045 C CD1 . LEU B 1 18  ? -20.662 -44.740 22.547  1.000 25.682 0 53  LEU B CD1 1 ? 
ATOM   2046 C CD2 . LEU B 1 18  ? -19.543 -43.758 20.598  1.000 26.927 0 53  LEU B CD2 1 ? 
ATOM   2047 N N   . GLY B 1 19  ? -19.102 -47.668 17.834  1.000 20.405 0 54  GLY B N   1 ? 
ATOM   2048 C CA  . GLY B 1 19  ? -18.680 -48.952 17.313  1.000 21.360 0 54  GLY B CA  1 ? 
ATOM   2049 C C   . GLY B 1 19  ? -18.508 -49.985 18.423  1.000 21.995 0 54  GLY B C   1 ? 
ATOM   2050 O O   . GLY B 1 19  ? -18.890 -49.747 19.559  1.000 21.229 0 54  GLY B O   1 ? 
ATOM   2051 N N   . PRO B 1 20  ? -17.898 -51.148 18.121  1.000 21.967 0 55  PRO B N   1 ? 
ATOM   2052 C CA  . PRO B 1 20  ? -17.794 -52.247 19.084  1.000 22.248 0 55  PRO B CA  1 ? 
ATOM   2053 C C   . PRO B 1 20  ? -16.835 -52.051 20.258  1.000 22.032 0 55  PRO B C   1 ? 
ATOM   2054 O O   . PRO B 1 20  ? -16.882 -52.831 21.216  1.000 21.842 0 55  PRO B O   1 ? 
ATOM   2055 C CB  . PRO B 1 20  ? -17.262 -53.437 18.269  1.000 23.581 0 55  PRO B CB  1 ? 
ATOM   2056 C CG  . PRO B 1 20  ? -17.158 -52.974 16.827  1.000 23.817 0 55  PRO B CG  1 ? 
ATOM   2057 C CD  . PRO B 1 20  ? -17.333 -51.467 16.806  1.000 22.882 0 55  PRO B CD  1 ? 
ATOM   2058 N N   . PHE B 1 21  ? -15.958 -51.029 20.191  1.000 19.826 0 56  PHE B N   1 ? 
ATOM   2059 C CA  . PHE B 1 21  ? -14.909 -50.889 21.182  1.000 19.720 0 56  PHE B CA  1 ? 
ATOM   2060 C C   . PHE B 1 21  ? -15.293 -49.856 22.230  1.000 20.028 0 56  PHE B C   1 ? 
ATOM   2061 O O   . PHE B 1 21  ? -15.717 -48.749 21.898  1.000 18.191 0 56  PHE B O   1 ? 
ATOM   2062 C CB  . PHE B 1 21  ? -13.566 -50.554 20.530  1.000 19.698 0 56  PHE B CB  1 ? 
ATOM   2063 C CG  . PHE B 1 21  ? -13.117 -51.607 19.556  1.000 19.832 0 56  PHE B CG  1 ? 
ATOM   2064 C CD1 . PHE B 1 21  ? -12.569 -52.800 20.001  1.000 21.400 0 56  PHE B CD1 1 ? 
ATOM   2065 C CD2 . PHE B 1 21  ? -13.300 -51.441 18.195  1.000 20.261 0 56  PHE B CD2 1 ? 
ATOM   2066 C CE1 . PHE B 1 21  ? -12.219 -53.798 19.103  1.000 21.281 0 56  PHE B CE1 1 ? 
ATOM   2067 C CE2 . PHE B 1 21  ? -12.949 -52.443 17.296  1.000 20.340 0 56  PHE B CE2 1 ? 
ATOM   2068 C CZ  . PHE B 1 21  ? -12.405 -53.615 17.753  1.000 21.035 0 56  PHE B CZ  1 ? 
ATOM   2069 N N   . GLU B 1 22  ? -15.165 -50.277 23.496  1.000 18.322 0 57  GLU B N   1 ? 
ATOM   2070 C CA  . GLU B 1 22  ? -15.080 -49.370 24.630  1.000 18.840 0 57  GLU B CA  1 ? 
ATOM   2071 C C   . GLU B 1 22  ? -13.812 -48.529 24.453  1.000 18.182 0 57  GLU B C   1 ? 
ATOM   2072 O O   . GLU B 1 22  ? -12.805 -49.003 23.929  1.000 16.979 0 57  GLU B O   1 ? 
ATOM   2073 C CB  . GLU B 1 22  ? -15.052 -50.155 25.949  1.000 19.471 0 57  GLU B CB  1 ? 
ATOM   2074 C CG  . GLU B 1 22  ? -15.048 -49.302 27.222  1.000 20.474 0 57  GLU B CG  1 ? 
ATOM   2075 C CD  . GLU B 1 22  ? -16.226 -48.343 27.386  1.000 23.495 0 57  GLU B CD  1 ? 
ATOM   2076 O OE1 . GLU B 1 22  ? -16.251 -47.328 26.647  1.000 27.283 0 57  GLU B OE1 1 ? 
ATOM   2077 O OE2 . GLU B 1 22  ? -17.127 -48.591 28.237  1.000 24.754 0 57  GLU B OE2 1 ? 
ATOM   2078 N N   . VAL B 1 23  ? -13.881 -47.280 24.929  1.000 18.802 0 58  VAL B N   1 ? 
ATOM   2079 C CA  . VAL B 1 23  ? -12.859 -46.277 24.706  1.000 18.348 0 58  VAL B CA  1 ? 
ATOM   2080 C C   . VAL B 1 23  ? -12.307 -45.837 26.056  1.000 18.399 0 58  VAL B C   1 ? 
ATOM   2081 O O   . VAL B 1 23  ? -13.070 -45.537 26.980  1.000 18.382 0 58  VAL B O   1 ? 
ATOM   2082 C CB  . VAL B 1 23  ? -13.458 -45.101 23.917  1.000 18.295 0 58  VAL B CB  1 ? 
ATOM   2083 C CG1 . VAL B 1 23  ? -12.460 -43.973 23.780  1.000 19.815 0 58  VAL B CG1 1 ? 
ATOM   2084 C CG2 . VAL B 1 23  ? -13.974 -45.551 22.553  1.000 18.845 0 58  VAL B CG2 1 ? 
ATOM   2085 N N   . GLY B 1 24  ? -10.976 -45.845 26.159  1.000 19.027 0 59  GLY B N   1 ? 
ATOM   2086 C CA  . GLY B 1 24  ? -10.262 -45.180 27.238  1.000 19.204 0 59  GLY B CA  1 ? 
ATOM   2087 C C   . GLY B 1 24  ? -9.690  -43.852 26.738  1.000 20.206 0 59  GLY B C   1 ? 
ATOM   2088 O O   . GLY B 1 24  ? -9.525  -43.667 25.520  1.000 17.490 0 59  GLY B O   1 ? 
ATOM   2089 N N   . THR B 1 25  ? -9.431  -42.938 27.677  1.000 19.263 0 60  THR B N   1 ? 
ATOM   2090 C CA  . THR B 1 25  ? -8.788  -41.676 27.341  1.000 22.825 0 60  THR B CA  1 ? 
ATOM   2091 C C   . THR B 1 25  ? -7.556  -41.445 28.209  1.000 21.596 0 60  THR B C   1 ? 
ATOM   2092 O O   . THR B 1 25  ? -7.484  -41.873 29.356  1.000 24.150 0 60  THR B O   1 ? 
ATOM   2093 C CB  . THR B 1 25  ? -9.728  -40.474 27.454  1.000 22.990 0 60  THR B CB  1 ? 
ATOM   2094 O OG1 . THR B 1 25  ? -10.076 -40.409 28.827  1.000 26.914 0 60  THR B OG1 1 ? 
ATOM   2095 C CG2 . THR B 1 25  ? -10.965 -40.589 26.606  1.000 23.532 0 60  THR B CG2 1 ? 
ATOM   2096 N N   . TYR B 1 26  ? -6.573  -40.785 27.613  1.000 21.274 0 61  TYR B N   1 ? 
ATOM   2097 C CA  . TYR B 1 26  ? -5.403  -40.337 28.325  1.000 19.915 0 61  TYR B CA  1 ? 
ATOM   2098 C C   . TYR B 1 26  ? -5.164  -38.879 27.955  1.000 19.926 0 61  TYR B C   1 ? 
ATOM   2099 O O   . TYR B 1 26  ? -5.096  -38.559 26.767  1.000 19.402 0 61  TYR B O   1 ? 
ATOM   2100 C CB  . TYR B 1 26  ? -4.213  -41.225 27.971  1.000 21.559 0 61  TYR B CB  1 ? 
ATOM   2101 C CG  . TYR B 1 26  ? -2.947  -40.757 28.630  1.000 20.638 0 61  TYR B CG  1 ? 
ATOM   2102 C CD1 . TYR B 1 26  ? -2.744  -41.009 29.974  1.000 20.961 0 61  TYR B CD1 1 ? 
ATOM   2103 C CD2 . TYR B 1 26  ? -2.007  -40.000 27.948  1.000 20.037 0 61  TYR B CD2 1 ? 
ATOM   2104 C CE1 . TYR B 1 26  ? -1.601  -40.574 30.616  1.000 20.514 0 61  TYR B CE1 1 ? 
ATOM   2105 C CE2 . TYR B 1 26  ? -0.859  -39.557 28.581  1.000 20.442 0 61  TYR B CE2 1 ? 
ATOM   2106 C CZ  . TYR B 1 26  ? -0.662  -39.848 29.919  1.000 20.360 0 61  TYR B CZ  1 ? 
ATOM   2107 O OH  . TYR B 1 26  ? 0.457   -39.439 30.584  1.000 23.909 0 61  TYR B OH  1 ? 
ATOM   2108 N N   . THR B 1 27  ? -5.059  -38.019 28.972  1.000 19.492 0 62  THR B N   1 ? 
ATOM   2109 C CA  . THR B 1 27  ? -4.848  -36.598 28.782  1.000 20.367 0 62  THR B CA  1 ? 
ATOM   2110 C C   . THR B 1 27  ? -3.352  -36.315 28.799  1.000 20.643 0 62  THR B C   1 ? 
ATOM   2111 O O   . THR B 1 27  ? -2.658  -36.642 29.762  1.000 20.397 0 62  THR B O   1 ? 
ATOM   2112 C CB  . THR B 1 27  ? -5.570  -35.754 29.845  1.000 20.579 0 62  THR B CB  1 ? 
ATOM   2113 O OG1 . THR B 1 27  ? -6.955  -36.067 29.767  1.000 23.988 0 62  THR B OG1 1 ? 
ATOM   2114 C CG2 . THR B 1 27  ? -5.402  -34.259 29.648  1.000 20.339 0 62  THR B CG2 1 ? 
ATOM   2115 N N   . VAL B 1 28  ? -2.886  -35.681 27.717  1.000 19.385 0 63  VAL B N   1 ? 
ATOM   2116 C CA  . VAL B 1 28  ? -1.483  -35.352 27.539  1.000 19.536 0 63  VAL B CA  1 ? 
ATOM   2117 C C   . VAL B 1 28  ? -1.297  -33.878 27.903  1.000 18.927 0 63  VAL B C   1 ? 
ATOM   2118 O O   . VAL B 1 28  ? -1.690  -32.999 27.146  1.000 19.439 0 63  VAL B O   1 ? 
ATOM   2119 C CB  . VAL B 1 28  ? -1.045  -35.618 26.082  1.000 20.082 0 63  VAL B CB  1 ? 
ATOM   2120 C CG1 . VAL B 1 28  ? 0.400   -35.192 25.855  1.000 20.604 0 63  VAL B CG1 1 ? 
ATOM   2121 C CG2 . VAL B 1 28  ? -1.278  -37.063 25.659  1.000 20.257 0 63  VAL B CG2 1 ? 
ATOM   2122 N N   . PRO B 1 29  ? -0.670  -33.527 29.044  1.000 19.076 0 64  PRO B N   1 ? 
ATOM   2123 C CA  . PRO B 1 29  ? -0.468  -32.118 29.370  1.000 20.397 0 64  PRO B CA  1 ? 
ATOM   2124 C C   . PRO B 1 29  ? 0.479   -31.430 28.384  1.000 20.002 0 64  PRO B C   1 ? 
ATOM   2125 O O   . PRO B 1 29  ? 1.399   -32.045 27.852  1.000 21.092 0 64  PRO B O   1 ? 
ATOM   2126 C CB  . PRO B 1 29  ? 0.146   -32.151 30.777  1.000 22.460 0 64  PRO B CB  1 ? 
ATOM   2127 C CG  . PRO B 1 29  ? -0.132  -33.574 31.281  1.000 22.641 0 64  PRO B CG  1 ? 
ATOM   2128 C CD  . PRO B 1 29  ? -0.095  -34.443 30.042  1.000 19.877 0 64  PRO B CD  1 ? 
ATOM   2129 N N   . ALA B 1 30  ? 0.246   -30.145 28.134  1.000 20.189 0 65  ALA B N   1 ? 
ATOM   2130 C CA  . ALA B 1 30  ? 1.140   -29.301 27.352  1.000 19.946 0 65  ALA B CA  1 ? 
ATOM   2131 C C   . ALA B 1 30  ? 2.578   -29.371 27.871  1.000 22.007 0 65  ALA B C   1 ? 
ATOM   2132 O O   . ALA B 1 30  ? 3.519   -29.353 27.083  1.000 21.193 0 65  ALA B O   1 ? 
ATOM   2133 C CB  . ALA B 1 30  ? 0.624   -27.876 27.385  1.000 21.094 0 65  ALA B CB  1 ? 
ATOM   2134 N N   . SER B 1 31  ? 2.739   -29.479 29.195  1.000 23.621 0 66  SER B N   1 ? 
ATOM   2135 C CA  . SER B 1 31  ? 4.045   -29.458 29.839  1.000 25.108 0 66  SER B CA  1 ? 
ATOM   2136 C C   . SER B 1 31  ? 4.820   -30.753 29.601  1.000 25.432 0 66  SER B C   1 ? 
ATOM   2137 O O   . SER B 1 31  ? 5.985   -30.820 29.983  1.000 28.583 0 66  SER B O   1 ? 
ATOM   2138 C CB  . SER B 1 31  ? 3.903   -29.186 31.317  1.000 26.289 0 66  SER B CB  1 ? 
ATOM   2139 O OG  . SER B 1 31  ? 3.055   -30.154 31.917  1.000 29.790 0 66  SER B OG  1 ? 
ATOM   2140 N N   . SER B 1 32  ? 4.196   -31.783 29.011  1.000 24.208 0 67  SER B N   1 ? 
ATOM   2141 C CA  . SER B 1 32  ? 4.877   -33.051 28.810  1.000 23.163 0 67  SER B CA  1 ? 
ATOM   2142 C C   . SER B 1 32  ? 5.386   -33.217 27.373  1.000 23.003 0 67  SER B C   1 ? 
ATOM   2143 O O   . SER B 1 32  ? 6.024   -34.225 27.083  1.000 23.854 0 67  SER B O   1 ? 
ATOM   2144 C CB  . SER B 1 32  ? 3.980   -34.216 29.220  1.000 23.700 0 67  SER B CB  1 ? 
ATOM   2145 O OG  . SER B 1 32  ? 2.898   -34.342 28.314  1.000 24.469 0 67  SER B OG  1 ? 
ATOM   2146 N N   . VAL B 1 33  ? 5.108   -32.269 26.468  1.000 20.699 0 68  VAL B N   1 ? 
ATOM   2147 C CA  . VAL B 1 33  ? 5.375   -32.442 25.048  1.000 20.287 0 68  VAL B CA  1 ? 
ATOM   2148 C C   . VAL B 1 33  ? 5.956   -31.159 24.444  1.000 19.134 0 68  VAL B C   1 ? 
ATOM   2149 O O   . VAL B 1 33  ? 5.804   -30.082 25.003  1.000 18.388 0 68  VAL B O   1 ? 
ATOM   2150 C CB  . VAL B 1 33  ? 4.101   -32.854 24.273  1.000 21.218 0 68  VAL B CB  1 ? 
ATOM   2151 C CG1 . VAL B 1 33  ? 3.556   -34.208 24.705  1.000 22.117 0 68  VAL B CG1 1 ? 
ATOM   2152 C CG2 . VAL B 1 33  ? 2.988   -31.808 24.344  1.000 21.977 0 68  VAL B CG2 1 ? 
ATOM   2153 N N   . THR B 1 34  ? 6.566   -31.278 23.249  1.000 19.532 0 69  THR B N   1 ? 
ATOM   2154 C CA  A THR B 1 34  ? 6.966   -30.104 22.488  0.500 20.633 0 69  THR B CA  1 ? 
ATOM   2155 C CA  B THR B 1 34  ? 7.028   -30.137 22.461  0.500 20.958 0 69  THR B CA  1 ? 
ATOM   2156 C C   . THR B 1 34  ? 6.293   -30.107 21.119  1.000 20.570 0 69  THR B C   1 ? 
ATOM   2157 O O   . THR B 1 34  ? 6.048   -31.163 20.535  1.000 24.110 0 69  THR B O   1 ? 
ATOM   2158 C CB  A THR B 1 34  ? 8.489   -30.043 22.319  0.500 20.715 0 69  THR B CB  1 ? 
ATOM   2159 C CB  B THR B 1 34  ? 8.539   -30.214 22.161  0.500 21.130 0 69  THR B CB  1 ? 
ATOM   2160 O OG1 A THR B 1 34  ? 8.883   -31.184 21.555  0.500 18.809 0 69  THR B OG1 1 ? 
ATOM   2161 O OG1 B THR B 1 34  ? 9.285   -30.200 23.376  0.500 21.644 0 69  THR B OG1 1 ? 
ATOM   2162 C CG2 A THR B 1 34  ? 9.207   -30.006 23.646  0.500 20.972 0 69  THR B CG2 1 ? 
ATOM   2163 C CG2 B THR B 1 34  ? 9.040   -29.081 21.288  0.500 20.322 0 69  THR B CG2 1 ? 
ATOM   2164 N N   . GLY B 1 35  ? 6.026   -28.907 20.604  1.000 18.922 0 70  GLY B N   1 ? 
ATOM   2165 C CA  . GLY B 1 35  ? 5.538   -28.747 19.239  1.000 18.752 0 70  GLY B CA  1 ? 
ATOM   2166 C C   . GLY B 1 35  ? 4.012   -28.629 19.143  1.000 18.230 0 70  GLY B C   1 ? 
ATOM   2167 O O   . GLY B 1 35  ? 3.480   -28.292 18.086  1.000 17.368 0 70  GLY B O   1 ? 
ATOM   2168 N N   . PHE B 1 36  ? 3.315   -28.930 20.243  1.000 17.972 0 71  PHE B N   1 ? 
ATOM   2169 C CA  . PHE B 1 36  ? 1.868   -28.791 20.300  1.000 17.377 0 71  PHE B CA  1 ? 
ATOM   2170 C C   . PHE B 1 36  ? 1.460   -28.618 21.762  1.000 16.318 0 71  PHE B C   1 ? 
ATOM   2171 O O   . PHE B 1 36  ? 2.273   -28.869 22.658  1.000 14.295 0 71  PHE B O   1 ? 
ATOM   2172 C CB  . PHE B 1 36  ? 1.192   -29.967 19.579  1.000 18.048 0 71  PHE B CB  1 ? 
ATOM   2173 C CG  . PHE B 1 36  ? 1.379   -31.306 20.240  1.000 17.425 0 71  PHE B CG  1 ? 
ATOM   2174 C CD1 . PHE B 1 36  ? 2.561   -32.011 20.120  1.000 18.356 0 71  PHE B CD1 1 ? 
ATOM   2175 C CD2 . PHE B 1 36  ? 0.371   -31.844 21.017  1.000 17.849 0 71  PHE B CD2 1 ? 
ATOM   2176 C CE1 . PHE B 1 36  ? 2.731   -33.231 20.755  1.000 18.279 0 71  PHE B CE1 1 ? 
ATOM   2177 C CE2 . PHE B 1 36  ? 0.529   -33.081 21.628  1.000 18.820 0 71  PHE B CE2 1 ? 
ATOM   2178 C CZ  . PHE B 1 36  ? 1.713   -33.764 21.518  1.000 18.999 0 71  PHE B CZ  1 ? 
ATOM   2179 N N   . GLY B 1 37  ? 0.198   -28.204 22.003  1.000 15.719 0 72  GLY B N   1 ? 
ATOM   2180 C CA  . GLY B 1 37  ? -0.215  -27.822 23.350  1.000 15.147 0 72  GLY B CA  1 ? 
ATOM   2181 C C   . GLY B 1 37  ? -0.812  -28.991 24.135  1.000 14.857 0 72  GLY B C   1 ? 
ATOM   2182 O O   . GLY B 1 37  ? -1.763  -28.805 24.862  1.000 15.774 0 72  GLY B O   1 ? 
ATOM   2183 N N   . GLY B 1 38  ? -0.280  -30.198 23.956  1.000 15.863 0 73  GLY B N   1 ? 
ATOM   2184 C CA  . GLY B 1 38  ? -0.865  -31.389 24.548  1.000 17.431 0 73  GLY B CA  1 ? 
ATOM   2185 C C   . GLY B 1 38  ? -2.129  -31.796 23.797  1.000 17.938 0 73  GLY B C   1 ? 
ATOM   2186 O O   . GLY B 1 38  ? -2.351  -31.340 22.669  1.000 19.116 0 73  GLY B O   1 ? 
ATOM   2187 N N   . GLY B 1 39  ? -2.942  -32.643 24.428  1.000 16.580 0 74  GLY B N   1 ? 
ATOM   2188 C CA  . GLY B 1 39  ? -4.211  -33.036 23.850  1.000 17.286 0 74  GLY B CA  1 ? 
ATOM   2189 C C   . GLY B 1 39  ? -4.817  -34.223 24.595  1.000 17.436 0 74  GLY B C   1 ? 
ATOM   2190 O O   . GLY B 1 39  ? -4.489  -34.473 25.758  1.000 18.213 0 74  GLY B O   1 ? 
ATOM   2191 N N   . VAL B 1 40  ? -5.695  -34.962 23.910  1.000 16.454 0 75  VAL B N   1 ? 
ATOM   2192 C CA  . VAL B 1 40  ? -6.401  -36.084 24.521  1.000 15.816 0 75  VAL B CA  1 ? 
ATOM   2193 C C   . VAL B 1 40  ? -6.363  -37.257 23.556  1.000 14.944 0 75  VAL B C   1 ? 
ATOM   2194 O O   . VAL B 1 40  ? -6.678  -37.097 22.385  1.000 13.642 0 75  VAL B O   1 ? 
ATOM   2195 C CB  . VAL B 1 40  ? -7.859  -35.734 24.857  1.000 15.827 0 75  VAL B CB  1 ? 
ATOM   2196 C CG1 . VAL B 1 40  ? -8.552  -36.917 25.501  1.000 17.833 0 75  VAL B CG1 1 ? 
ATOM   2197 C CG2 . VAL B 1 40  ? -7.983  -34.471 25.716  1.000 16.371 0 75  VAL B CG2 1 ? 
ATOM   2198 N N   . ILE B 1 41  ? -5.947  -38.420 24.064  1.000 15.344 0 76  ILE B N   1 ? 
ATOM   2199 C CA  . ILE B 1 41  ? -5.883  -39.640 23.281  1.000 15.791 0 76  ILE B CA  1 ? 
ATOM   2200 C C   . ILE B 1 41  ? -7.085  -40.498 23.649  1.000 16.410 0 76  ILE B C   1 ? 
ATOM   2201 O O   . ILE B 1 41  ? -7.285  -40.800 24.835  1.000 17.906 0 76  ILE B O   1 ? 
ATOM   2202 C CB  . ILE B 1 41  ? -4.573  -40.420 23.520  1.000 15.913 0 76  ILE B CB  1 ? 
ATOM   2203 C CG1 . ILE B 1 41  ? -3.340  -39.521 23.444  1.000 16.685 0 76  ILE B CG1 1 ? 
ATOM   2204 C CG2 . ILE B 1 41  ? -4.456  -41.581 22.531  1.000 16.231 0 76  ILE B CG2 1 ? 
ATOM   2205 C CD1 . ILE B 1 41  ? -2.039  -40.231 23.726  1.000 17.278 0 76  ILE B CD1 1 ? 
ATOM   2206 N N   . TYR B 1 42  ? -7.854  -40.876 22.621  1.000 16.268 0 77  TYR B N   1 ? 
ATOM   2207 C CA  . TYR B 1 42  ? -8.929  -41.845 22.745  1.000 17.865 0 77  TYR B CA  1 ? 
ATOM   2208 C C   . TYR B 1 42  ? -8.463  -43.154 22.121  1.000 17.059 0 77  TYR B C   1 ? 
ATOM   2209 O O   . TYR B 1 42  ? -8.014  -43.141 20.987  1.000 18.366 0 77  TYR B O   1 ? 
ATOM   2210 C CB  . TYR B 1 42  ? -10.199 -41.357 22.035  1.000 18.073 0 77  TYR B CB  1 ? 
ATOM   2211 C CG  . TYR B 1 42  ? -10.667 -39.988 22.435  1.000 17.668 0 77  TYR B CG  1 ? 
ATOM   2212 C CD1 . TYR B 1 42  ? -10.037 -38.834 21.968  1.000 19.621 0 77  TYR B CD1 1 ? 
ATOM   2213 C CD2 . TYR B 1 42  ? -11.716 -39.838 23.308  1.000 19.894 0 77  TYR B CD2 1 ? 
ATOM   2214 C CE1 . TYR B 1 42  ? -10.462 -37.573 22.350  1.000 17.861 0 77  TYR B CE1 1 ? 
ATOM   2215 C CE2 . TYR B 1 42  ? -12.133 -38.587 23.731  1.000 20.557 0 77  TYR B CE2 1 ? 
ATOM   2216 C CZ  . TYR B 1 42  ? -11.506 -37.452 23.246  1.000 19.885 0 77  TYR B CZ  1 ? 
ATOM   2217 O OH  . TYR B 1 42  ? -11.942 -36.232 23.689  1.000 19.269 0 77  TYR B OH  1 ? 
ATOM   2218 N N   . TYR B 1 43  ? -8.574  -44.281 22.838  1.000 18.772 0 78  TYR B N   1 ? 
ATOM   2219 C CA  . TYR B 1 43  ? -8.108  -45.553 22.310  1.000 20.025 0 78  TYR B CA  1 ? 
ATOM   2220 C C   . TYR B 1 43  ? -8.990  -46.702 22.796  1.000 19.891 0 78  TYR B C   1 ? 
ATOM   2221 O O   . TYR B 1 43  ? -9.572  -46.639 23.886  1.000 19.998 0 78  TYR B O   1 ? 
ATOM   2222 C CB  . TYR B 1 43  ? -6.646  -45.804 22.681  1.000 22.337 0 78  TYR B CB  1 ? 
ATOM   2223 C CG  . TYR B 1 43  ? -6.366  -45.703 24.159  1.000 23.948 0 78  TYR B CG  1 ? 
ATOM   2224 C CD1 . TYR B 1 43  ? -6.142  -44.484 24.768  1.000 25.494 0 78  TYR B CD1 1 ? 
ATOM   2225 C CD2 . TYR B 1 43  ? -6.385  -46.835 24.955  1.000 25.607 0 78  TYR B CD2 1 ? 
ATOM   2226 C CE1 . TYR B 1 43  ? -5.908  -44.389 26.131  1.000 28.122 0 78  TYR B CE1 1 ? 
ATOM   2227 C CE2 . TYR B 1 43  ? -6.170  -46.764 26.320  1.000 27.131 0 78  TYR B CE2 1 ? 
ATOM   2228 C CZ  . TYR B 1 43  ? -5.940  -45.533 26.912  1.000 31.322 0 78  TYR B CZ  1 ? 
ATOM   2229 O OH  . TYR B 1 43  ? -5.722  -45.428 28.264  1.000 34.936 0 78  TYR B OH  1 ? 
ATOM   2230 N N   . PRO B 1 44  ? -9.122  -47.775 21.979  1.000 18.066 0 79  PRO B N   1 ? 
ATOM   2231 C CA  . PRO B 1 44  ? -9.837  -48.977 22.403  1.000 17.997 0 79  PRO B CA  1 ? 
ATOM   2232 C C   . PRO B 1 44  ? -9.222  -49.614 23.648  1.000 16.294 0 79  PRO B C   1 ? 
ATOM   2233 O O   . PRO B 1 44  ? -8.006  -49.718 23.760  1.000 14.189 0 79  PRO B O   1 ? 
ATOM   2234 C CB  . PRO B 1 44  ? -9.807  -49.912 21.180  1.000 17.403 0 79  PRO B CB  1 ? 
ATOM   2235 C CG  . PRO B 1 44  ? -9.530  -49.008 20.000  1.000 17.578 0 79  PRO B CG  1 ? 
ATOM   2236 C CD  . PRO B 1 44  ? -8.732  -47.840 20.558  1.000 19.075 0 79  PRO B CD  1 ? 
ATOM   2237 N N   . VAL B 1 45  ? -10.096 -50.007 24.575  1.000 16.117 0 80  VAL B N   1 ? 
ATOM   2238 C CA  . VAL B 1 45  ? -9.725  -50.828 25.718  1.000 17.883 0 80  VAL B CA  1 ? 
ATOM   2239 C C   . VAL B 1 45  ? -10.484 -52.161 25.633  1.000 19.453 0 80  VAL B C   1 ? 
ATOM   2240 O O   . VAL B 1 45  ? -11.426 -52.297 24.836  1.000 18.707 0 80  VAL B O   1 ? 
ATOM   2241 C CB  . VAL B 1 45  ? -10.020 -50.097 27.046  1.000 18.000 0 80  VAL B CB  1 ? 
ATOM   2242 C CG1 . VAL B 1 45  ? -9.156  -48.842 27.208  1.000 19.661 0 80  VAL B CG1 1 ? 
ATOM   2243 C CG2 . VAL B 1 45  ? -11.495 -49.772 27.233  1.000 17.211 0 80  VAL B CG2 1 ? 
ATOM   2244 N N   . ASN B 1 46  ? -10.048 -53.139 26.456  1.000 20.631 0 81  ASN B N   1 ? 
ATOM   2245 C CA  . ASN B 1 46  ? -10.664 -54.466 26.543  1.000 20.378 0 81  ASN B CA  1 ? 
ATOM   2246 C C   . ASN B 1 46  ? -10.490 -55.206 25.215  1.000 22.447 0 81  ASN B C   1 ? 
ATOM   2247 O O   . ASN B 1 46  ? -11.438 -55.781 24.700  1.000 24.177 0 81  ASN B O   1 ? 
ATOM   2248 C CB  . ASN B 1 46  ? -12.144 -54.387 26.964  1.000 20.753 0 81  ASN B CB  1 ? 
ATOM   2249 C CG  . ASN B 1 46  ? -12.282 -54.028 28.435  1.000 19.858 0 81  ASN B CG  1 ? 
ATOM   2250 O OD1 . ASN B 1 46  ? -11.361 -54.231 29.218  1.000 18.031 0 81  ASN B OD1 1 ? 
ATOM   2251 N ND2 . ASN B 1 46  ? -13.403 -53.454 28.817  1.000 18.883 0 81  ASN B ND2 1 ? 
ATOM   2252 N N   . THR B 1 47  ? -9.276  -55.137 24.660  1.000 21.988 0 82  THR B N   1 ? 
ATOM   2253 C CA  . THR B 1 47  ? -8.940  -55.695 23.360  1.000 23.904 0 82  THR B CA  1 ? 
ATOM   2254 C C   . THR B 1 47  ? -7.419  -55.818 23.323  1.000 26.937 0 82  THR B C   1 ? 
ATOM   2255 O O   . THR B 1 47  ? -6.721  -55.003 23.930  1.000 27.758 0 82  THR B O   1 ? 
ATOM   2256 C CB  . THR B 1 47  ? -9.457  -54.824 22.200  1.000 23.088 0 82  THR B CB  1 ? 
ATOM   2257 O OG1 . THR B 1 47  ? -9.072  -55.422 20.962  1.000 24.079 0 82  THR B OG1 1 ? 
ATOM   2258 C CG2 . THR B 1 47  ? -8.907  -53.413 22.183  1.000 23.553 0 82  THR B CG2 1 ? 
ATOM   2259 N N   . ASP B 1 48  ? -6.909  -56.838 22.623  1.000 29.808 0 83  ASP B N   1 ? 
ATOM   2260 C CA  . ASP B 1 48  ? -5.472  -56.981 22.427  1.000 33.047 0 83  ASP B CA  1 ? 
ATOM   2261 C C   . ASP B 1 48  ? -5.093  -56.568 20.997  1.000 30.266 0 83  ASP B C   1 ? 
ATOM   2262 O O   . ASP B 1 48  ? -3.949  -56.688 20.589  1.000 31.803 0 83  ASP B O   1 ? 
ATOM   2263 C CB  . ASP B 1 48  ? -5.021  -58.396 22.794  1.000 37.086 0 83  ASP B CB  1 ? 
ATOM   2264 C CG  . ASP B 1 48  ? -5.799  -59.474 22.060  1.000 47.690 0 83  ASP B CG  1 ? 
ATOM   2265 O OD1 . ASP B 1 48  ? -6.590  -59.133 21.144  1.000 51.492 0 83  ASP B OD1 1 ? 
ATOM   2266 O OD2 . ASP B 1 48  ? -5.627  -60.652 22.424  1.000 63.862 0 83  ASP B OD2 1 ? 
ATOM   2267 N N   . LYS B 1 49  ? -6.053  -56.059 20.225  1.000 28.086 0 84  LYS B N   1 ? 
ATOM   2268 C CA  . LYS B 1 49  ? -5.790  -55.716 18.836  1.000 27.009 0 84  LYS B CA  1 ? 
ATOM   2269 C C   . LYS B 1 49  ? -4.991  -54.413 18.733  1.000 24.140 0 84  LYS B C   1 ? 
ATOM   2270 O O   . LYS B 1 49  ? -4.911  -53.634 19.680  1.000 20.999 0 84  LYS B O   1 ? 
ATOM   2271 C CB  . LYS B 1 49  ? -7.112  -55.600 18.084  1.000 27.823 0 84  LYS B CB  1 ? 
ATOM   2272 C CG  . LYS B 1 49  ? -7.875  -56.904 17.899  1.000 30.330 0 84  LYS B CG  1 ? 
ATOM   2273 C CD  . LYS B 1 49  ? -9.256  -56.653 17.314  1.000 32.807 0 84  LYS B CD  1 ? 
ATOM   2274 C CE  . LYS B 1 49  ? -10.116 -57.891 17.240  1.000 36.501 0 84  LYS B CE  1 ? 
ATOM   2275 N NZ  . LYS B 1 49  ? -9.716  -58.734 16.095  1.000 38.715 0 84  LYS B NZ  1 ? 
ATOM   2276 N N   . LYS B 1 50  ? -4.409  -54.205 17.546  1.000 23.631 0 85  LYS B N   1 ? 
ATOM   2277 C CA  . LYS B 1 50  ? -3.812  -52.946 17.142  1.000 24.088 0 85  LYS B CA  1 ? 
ATOM   2278 C C   . LYS B 1 50  ? -4.716  -52.282 16.107  1.000 21.756 0 85  LYS B C   1 ? 
ATOM   2279 O O   . LYS B 1 50  ? -5.431  -52.982 15.421  1.000 22.614 0 85  LYS B O   1 ? 
ATOM   2280 C CB  . LYS B 1 50  ? -2.406  -53.187 16.586  1.000 26.135 0 85  LYS B CB  1 ? 
ATOM   2281 C CG  . LYS B 1 50  ? -1.337  -53.413 17.644  1.000 30.811 0 85  LYS B CG  1 ? 
ATOM   2282 C CD  . LYS B 1 50  ? 0.057   -53.468 17.042  1.000 33.646 0 85  LYS B CD  1 ? 
ATOM   2283 C CE  . LYS B 1 50  ? 1.166   -53.393 18.062  1.000 36.721 0 85  LYS B CE  1 ? 
ATOM   2284 N NZ  . LYS B 1 50  ? 1.134   -52.121 18.831  1.000 36.891 0 85  LYS B NZ  1 ? 
ATOM   2285 N N   . PHE B 1 51  ? -4.654  -50.946 16.011  1.000 19.404 0 86  PHE B N   1 ? 
ATOM   2286 C CA  . PHE B 1 51  ? -5.561  -50.109 15.236  1.000 18.445 0 86  PHE B CA  1 ? 
ATOM   2287 C C   . PHE B 1 51  ? -4.789  -48.942 14.630  1.000 17.214 0 86  PHE B C   1 ? 
ATOM   2288 O O   . PHE B 1 51  ? -3.830  -48.448 15.231  1.000 18.471 0 86  PHE B O   1 ? 
ATOM   2289 C CB  . PHE B 1 51  ? -6.659  -49.514 16.130  1.000 18.079 0 86  PHE B CB  1 ? 
ATOM   2290 C CG  . PHE B 1 51  ? -7.455  -50.544 16.885  1.000 18.021 0 86  PHE B CG  1 ? 
ATOM   2291 C CD1 . PHE B 1 51  ? -8.503  -51.209 16.277  1.000 18.136 0 86  PHE B CD1 1 ? 
ATOM   2292 C CD2 . PHE B 1 51  ? -7.078  -50.918 18.163  1.000 18.688 0 86  PHE B CD2 1 ? 
ATOM   2293 C CE1 . PHE B 1 51  ? -9.196  -52.192 16.960  1.000 19.603 0 86  PHE B CE1 1 ? 
ATOM   2294 C CE2 . PHE B 1 51  ? -7.788  -51.889 18.856  1.000 20.145 0 86  PHE B CE2 1 ? 
ATOM   2295 C CZ  . PHE B 1 51  ? -8.853  -52.507 18.259  1.000 20.123 0 86  PHE B CZ  1 ? 
ATOM   2296 N N   . PRO B 1 52  ? -5.189  -48.429 13.449  1.000 16.829 0 87  PRO B N   1 ? 
ATOM   2297 C CA  . PRO B 1 52  ? -4.559  -47.236 12.901  1.000 16.570 0 87  PRO B CA  1 ? 
ATOM   2298 C C   . PRO B 1 52  ? -4.722  -46.044 13.847  1.000 17.422 0 87  PRO B C   1 ? 
ATOM   2299 O O   . PRO B 1 52  ? -5.668  -45.986 14.643  1.000 16.363 0 87  PRO B O   1 ? 
ATOM   2300 C CB  . PRO B 1 52  ? -5.275  -47.033 11.560  1.000 17.492 0 87  PRO B CB  1 ? 
ATOM   2301 C CG  . PRO B 1 52  ? -5.820  -48.411 11.206  1.000 17.631 0 87  PRO B CG  1 ? 
ATOM   2302 C CD  . PRO B 1 52  ? -6.188  -49.003 12.541  1.000 17.781 0 87  PRO B CD  1 ? 
ATOM   2303 N N   . GLY B 1 53  ? -3.785  -45.094 13.728  1.000 16.708 0 88  GLY B N   1 ? 
ATOM   2304 C CA  . GLY B 1 53  ? -3.828  -43.845 14.473  1.000 16.780 0 88  GLY B CA  1 ? 
ATOM   2305 C C   . GLY B 1 53  ? -4.367  -42.700 13.616  1.000 17.377 0 88  GLY B C   1 ? 
ATOM   2306 O O   . GLY B 1 53  ? -4.185  -42.691 12.408  1.000 17.353 0 88  GLY B O   1 ? 
ATOM   2307 N N   . ILE B 1 54  ? -5.072  -41.776 14.271  1.000 18.623 0 89  ILE B N   1 ? 
ATOM   2308 C CA  . ILE B 1 54  ? -5.572  -40.551 13.674  1.000 17.301 0 89  ILE B CA  1 ? 
ATOM   2309 C C   . ILE B 1 54  ? -5.210  -39.402 14.608  1.000 17.138 0 89  ILE B C   1 ? 
ATOM   2310 O O   . ILE B 1 54  ? -5.547  -39.443 15.791  1.000 15.722 0 89  ILE B O   1 ? 
ATOM   2311 C CB  . ILE B 1 54  ? -7.095  -40.611 13.453  1.000 17.110 0 89  ILE B CB  1 ? 
ATOM   2312 C CG1 . ILE B 1 54  ? -7.494  -41.821 12.593  1.000 17.445 0 89  ILE B CG1 1 ? 
ATOM   2313 C CG2 . ILE B 1 54  ? -7.562  -39.291 12.846  1.000 16.949 0 89  ILE B CG2 1 ? 
ATOM   2314 C CD1 . ILE B 1 54  ? -8.966  -42.133 12.563  1.000 16.863 0 89  ILE B CD1 1 ? 
ATOM   2315 N N   . VAL B 1 55  ? -4.530  -38.383 14.064  1.000 16.632 0 90  VAL B N   1 ? 
ATOM   2316 C CA  . VAL B 1 55  ? -4.296  -37.141 14.779  1.000 17.443 0 90  VAL B CA  1 ? 
ATOM   2317 C C   . VAL B 1 55  ? -5.200  -36.042 14.217  1.000 17.643 0 90  VAL B C   1 ? 
ATOM   2318 O O   . VAL B 1 55  ? -5.267  -35.857 13.008  1.000 16.890 0 90  VAL B O   1 ? 
ATOM   2319 C CB  . VAL B 1 55  ? -2.810  -36.762 14.703  1.000 18.944 0 90  VAL B CB  1 ? 
ATOM   2320 C CG1 . VAL B 1 55  ? -2.523  -35.494 15.478  1.000 20.301 0 90  VAL B CG1 1 ? 
ATOM   2321 C CG2 . VAL B 1 55  ? -1.949  -37.920 15.218  1.000 20.697 0 90  VAL B CG2 1 ? 
ATOM   2322 N N   . MET B 1 56  ? -5.866  -35.307 15.120  1.000 18.467 0 91  MET B N   1 ? 
ATOM   2323 C CA  . MET B 1 56  ? -6.877  -34.331 14.751  1.000 18.738 0 91  MET B CA  1 ? 
ATOM   2324 C C   . MET B 1 56  ? -6.568  -32.976 15.380  1.000 17.762 0 91  MET B C   1 ? 
ATOM   2325 O O   . MET B 1 56  ? -6.186  -32.900 16.546  1.000 16.591 0 91  MET B O   1 ? 
ATOM   2326 C CB  . MET B 1 56  ? -8.268  -34.772 15.218  1.000 20.873 0 91  MET B CB  1 ? 
ATOM   2327 C CG  . MET B 1 56  ? -8.713  -36.070 14.579  1.000 23.391 0 91  MET B CG  1 ? 
ATOM   2328 S SD  . MET B 1 56  ? -10.538 -36.289 14.484  1.000 27.721 0 91  MET B SD  1 ? 
ATOM   2329 C CE  . MET B 1 56  ? -11.051 -35.831 16.135  1.000 26.574 0 91  MET B CE  1 ? 
ATOM   2330 N N   . ALA B 1 57  ? -6.775  -31.906 14.597  1.000 16.761 0 92  ALA B N   1 ? 
ATOM   2331 C CA  . ALA B 1 57  ? -6.571  -30.555 15.073  1.000 16.528 0 92  ALA B CA  1 ? 
ATOM   2332 C C   . ALA B 1 57  ? -7.908  -29.828 15.102  1.000 16.913 0 92  ALA B C   1 ? 
ATOM   2333 O O   . ALA B 1 57  ? -8.611  -29.784 14.098  1.000 18.650 0 92  ALA B O   1 ? 
ATOM   2334 C CB  . ALA B 1 57  ? -5.599  -29.816 14.190  1.000 16.635 0 92  ALA B CB  1 ? 
ATOM   2335 N N   . PRO B 1 58  ? -8.279  -29.170 16.219  1.000 15.681 0 93  PRO B N   1 ? 
ATOM   2336 C CA  . PRO B 1 58  ? -9.505  -28.372 16.258  1.000 16.375 0 93  PRO B CA  1 ? 
ATOM   2337 C C   . PRO B 1 58  ? -9.274  -26.984 15.649  1.000 16.644 0 93  PRO B C   1 ? 
ATOM   2338 O O   . PRO B 1 58  ? -8.156  -26.625 15.265  1.000 16.350 0 93  PRO B O   1 ? 
ATOM   2339 C CB  . PRO B 1 58  ? -9.795  -28.331 17.766  1.000 16.224 0 93  PRO B CB  1 ? 
ATOM   2340 C CG  . PRO B 1 58  ? -8.413  -28.265 18.378  1.000 16.623 0 93  PRO B CG  1 ? 
ATOM   2341 C CD  . PRO B 1 58  ? -7.554  -29.149 17.491  1.000 16.130 0 93  PRO B CD  1 ? 
ATOM   2342 N N   . GLY B 1 59  ? -10.346 -26.207 15.548  1.000 14.360 0 94  GLY B N   1 ? 
ATOM   2343 C CA  . GLY B 1 59  ? -10.239 -24.853 15.055  1.000 14.565 0 94  GLY B CA  1 ? 
ATOM   2344 C C   . GLY B 1 59  ? -9.261  -24.003 15.867  1.000 14.039 0 94  GLY B C   1 ? 
ATOM   2345 O O   . GLY B 1 59  ? -8.855  -24.359 16.977  1.000 13.522 0 94  GLY B O   1 ? 
ATOM   2346 N N   . TYR B 1 60  ? -8.965  -22.830 15.314  1.000 13.875 0 95  TYR B N   1 ? 
ATOM   2347 C CA  . TYR B 1 60  ? -7.919  -21.953 15.812  1.000 14.892 0 95  TYR B CA  1 ? 
ATOM   2348 C C   . TYR B 1 60  ? -8.198  -21.527 17.257  1.000 14.770 0 95  TYR B C   1 ? 
ATOM   2349 O O   . TYR B 1 60  ? -7.330  -21.706 18.100  1.000 14.561 0 95  TYR B O   1 ? 
ATOM   2350 C CB  . TYR B 1 60  ? -7.771  -20.778 14.851  1.000 15.281 0 95  TYR B CB  1 ? 
ATOM   2351 C CG  . TYR B 1 60  ? -6.670  -19.803 15.190  1.000 15.877 0 95  TYR B CG  1 ? 
ATOM   2352 C CD1 . TYR B 1 60  ? -5.442  -20.233 15.673  1.000 15.932 0 95  TYR B CD1 1 ? 
ATOM   2353 C CD2 . TYR B 1 60  ? -6.839  -18.446 14.977  1.000 15.635 0 95  TYR B CD2 1 ? 
ATOM   2354 C CE1 . TYR B 1 60  ? -4.419  -19.340 15.929  1.000 15.732 0 95  TYR B CE1 1 ? 
ATOM   2355 C CE2 . TYR B 1 60  ? -5.823  -17.535 15.238  1.000 15.659 0 95  TYR B CE2 1 ? 
ATOM   2356 C CZ  . TYR B 1 60  ? -4.604  -17.987 15.721  1.000 16.512 0 95  TYR B CZ  1 ? 
ATOM   2357 O OH  . TYR B 1 60  ? -3.581  -17.113 16.031  1.000 16.416 0 95  TYR B OH  1 ? 
ATOM   2358 N N   . THR B 1 61  ? -9.422  -21.054 17.564  1.000 13.896 0 96  THR B N   1 ? 
ATOM   2359 C CA  . THR B 1 61  ? -9.721  -20.560 18.903  1.000 14.178 0 96  THR B CA  1 ? 
ATOM   2360 C C   . THR B 1 61  ? -10.142 -21.701 19.836  1.000 14.404 0 96  THR B C   1 ? 
ATOM   2361 O O   . THR B 1 61  ? -10.457 -21.446 20.986  1.000 13.469 0 96  THR B O   1 ? 
ATOM   2362 C CB  . THR B 1 61  ? -10.763 -19.435 18.895  1.000 13.710 0 96  THR B CB  1 ? 
ATOM   2363 O OG1 . THR B 1 61  ? -12.030 -19.956 18.506  1.000 13.961 0 96  THR B OG1 1 ? 
ATOM   2364 C CG2 . THR B 1 61  ? -10.360 -18.292 17.990  1.000 14.619 0 96  THR B CG2 1 ? 
ATOM   2365 N N   . ALA B 1 62  ? -10.109 -22.954 19.345  1.000 14.319 0 97  ALA B N   1 ? 
ATOM   2366 C CA  . ALA B 1 62  ? -10.662 -24.090 20.054  1.000 15.180 0 97  ALA B CA  1 ? 
ATOM   2367 C C   . ALA B 1 62  ? -9.557  -24.919 20.698  1.000 16.308 0 97  ALA B C   1 ? 
ATOM   2368 O O   . ALA B 1 62  ? -8.375  -24.768 20.388  1.000 15.892 0 97  ALA B O   1 ? 
ATOM   2369 C CB  . ALA B 1 62  ? -11.447 -24.920 19.084  1.000 16.738 0 97  ALA B CB  1 ? 
ATOM   2370 N N   . ASP B 1 63  ? -9.976  -25.808 21.601  1.000 16.804 0 98  ASP B N   1 ? 
ATOM   2371 C CA  . ASP B 1 63  ? -9.081  -26.816 22.132  1.000 17.219 0 98  ASP B CA  1 ? 
ATOM   2372 C C   . ASP B 1 63  ? -9.681  -28.182 21.818  1.000 17.875 0 98  ASP B C   1 ? 
ATOM   2373 O O   . ASP B 1 63  ? -10.725 -28.264 21.157  1.000 16.519 0 98  ASP B O   1 ? 
ATOM   2374 C CB  . ASP B 1 63  ? -8.793  -26.589 23.622  1.000 18.202 0 98  ASP B CB  1 ? 
ATOM   2375 C CG  . ASP B 1 63  ? -9.961  -26.780 24.563  1.000 18.787 0 98  ASP B CG  1 ? 
ATOM   2376 O OD1 . ASP B 1 63  ? -11.005 -27.350 24.127  1.000 19.802 0 98  ASP B OD1 1 ? 
ATOM   2377 O OD2 . ASP B 1 63  ? -9.802  -26.341 25.736  1.000 18.652 0 98  ASP B OD2 1 ? 
ATOM   2378 N N   . ALA B 1 64  ? -9.032  -29.237 22.342  1.000 17.749 0 99  ALA B N   1 ? 
ATOM   2379 C CA  . ALA B 1 64  ? -9.342  -30.603 21.956  1.000 18.399 0 99  ALA B CA  1 ? 
ATOM   2380 C C   . ALA B 1 64  ? -10.803 -30.953 22.248  1.000 19.142 0 99  ALA B C   1 ? 
ATOM   2381 O O   . ALA B 1 64  ? -11.387 -31.799 21.566  1.000 21.481 0 99  ALA B O   1 ? 
ATOM   2382 C CB  . ALA B 1 64  ? -8.413  -31.555 22.659  1.000 18.590 0 99  ALA B CB  1 ? 
ATOM   2383 N N   . SER B 1 65  ? -11.355 -30.316 23.289  1.000 17.933 0 100 SER B N   1 ? 
ATOM   2384 C CA  . SER B 1 65  ? -12.723 -30.507 23.727  1.000 17.558 0 100 SER B CA  1 ? 
ATOM   2385 C C   . SER B 1 65  ? -13.718 -30.296 22.583  1.000 16.225 0 100 SER B C   1 ? 
ATOM   2386 O O   . SER B 1 65  ? -14.758 -30.950 22.550  1.000 16.399 0 100 SER B O   1 ? 
ATOM   2387 C CB  . SER B 1 65  ? -12.999 -29.607 24.922  1.000 18.501 0 100 SER B CB  1 ? 
ATOM   2388 O OG  . SER B 1 65  ? -14.377 -29.636 25.264  1.000 21.439 0 100 SER B OG  1 ? 
ATOM   2389 N N   . SER B 1 66  ? -13.400 -29.432 21.608  1.000 15.371 0 101 SER B N   1 ? 
ATOM   2390 C CA  A SER B 1 66  ? -14.340 -29.099 20.547  0.500 14.830 0 101 SER B CA  1 ? 
ATOM   2391 C CA  B SER B 1 66  ? -14.345 -29.104 20.550  0.500 16.025 0 101 SER B CA  1 ? 
ATOM   2392 C C   . SER B 1 66  ? -14.543 -30.268 19.576  1.000 15.047 0 101 SER B C   1 ? 
ATOM   2393 O O   . SER B 1 66  ? -15.502 -30.265 18.823  1.000 15.638 0 101 SER B O   1 ? 
ATOM   2394 C CB  A SER B 1 66  ? -13.936 -27.829 19.828  0.500 13.818 0 101 SER B CB  1 ? 
ATOM   2395 C CB  B SER B 1 66  ? -13.928 -27.874 19.799  0.500 16.263 0 101 SER B CB  1 ? 
ATOM   2396 O OG  A SER B 1 66  ? -14.188 -26.676 20.626  0.500 12.516 0 101 SER B OG  1 ? 
ATOM   2397 O OG  B SER B 1 66  ? -12.996 -28.223 18.788  0.500 18.307 0 101 SER B OG  1 ? 
ATOM   2398 N N   . LEU B 1 67  ? -13.639 -31.260 19.574  1.000 16.249 0 102 LEU B N   1 ? 
ATOM   2399 C CA  . LEU B 1 67  ? -13.805 -32.450 18.743  1.000 16.826 0 102 LEU B CA  1 ? 
ATOM   2400 C C   . LEU B 1 67  ? -13.892 -33.715 19.611  1.000 17.882 0 102 LEU B C   1 ? 
ATOM   2401 O O   . LEU B 1 67  ? -13.686 -34.818 19.118  1.000 16.880 0 102 LEU B O   1 ? 
ATOM   2402 C CB  . LEU B 1 67  ? -12.642 -32.522 17.749  1.000 17.612 0 102 LEU B CB  1 ? 
ATOM   2403 C CG  . LEU B 1 67  ? -12.640 -31.466 16.635  1.000 19.501 0 102 LEU B CG  1 ? 
ATOM   2404 C CD1 . LEU B 1 67  ? -11.432 -31.619 15.704  1.000 19.799 0 102 LEU B CD1 1 ? 
ATOM   2405 C CD2 . LEU B 1 67  ? -13.927 -31.534 15.837  1.000 19.188 0 102 LEU B CD2 1 ? 
ATOM   2406 N N   . ASP B 1 68  ? -14.239 -33.562 20.897  1.000 17.829 0 103 ASP B N   1 ? 
ATOM   2407 C CA  . ASP B 1 68  ? -14.299 -34.695 21.813  1.000 19.803 0 103 ASP B CA  1 ? 
ATOM   2408 C C   . ASP B 1 68  ? -15.259 -35.764 21.284  1.000 17.806 0 103 ASP B C   1 ? 
ATOM   2409 O O   . ASP B 1 68  ? -14.932 -36.943 21.322  1.000 15.797 0 103 ASP B O   1 ? 
ATOM   2410 C CB  . ASP B 1 68  ? -14.670 -34.250 23.237  1.000 23.497 0 103 ASP B CB  1 ? 
ATOM   2411 C CG  . ASP B 1 68  ? -15.047 -35.411 24.151  1.000 28.800 0 103 ASP B CG  1 ? 
ATOM   2412 O OD1 . ASP B 1 68  ? -14.134 -36.107 24.651  1.000 36.981 0 103 ASP B OD1 1 ? 
ATOM   2413 O OD2 . ASP B 1 68  ? -16.256 -35.681 24.292  1.000 33.963 0 103 ASP B OD2 1 ? 
ATOM   2414 N N   . TRP B 1 69  ? -16.427 -35.360 20.765  1.000 16.089 0 104 TRP B N   1 ? 
ATOM   2415 C CA  . TRP B 1 69  ? -17.447 -36.312 20.354  1.000 15.963 0 104 TRP B CA  1 ? 
ATOM   2416 C C   . TRP B 1 69  ? -16.930 -37.196 19.224  1.000 16.884 0 104 TRP B C   1 ? 
ATOM   2417 O O   . TRP B 1 69  ? -17.214 -38.395 19.197  1.000 17.086 0 104 TRP B O   1 ? 
ATOM   2418 C CB  . TRP B 1 69  ? -18.754 -35.590 19.972  1.000 15.835 0 104 TRP B CB  1 ? 
ATOM   2419 C CG  . TRP B 1 69  ? -18.683 -34.904 18.634  1.000 15.909 0 104 TRP B CG  1 ? 
ATOM   2420 C CD1 . TRP B 1 69  ? -18.297 -33.618 18.388  1.000 16.189 0 104 TRP B CD1 1 ? 
ATOM   2421 C CD2 . TRP B 1 69  ? -18.965 -35.490 17.349  1.000 14.875 0 104 TRP B CD2 1 ? 
ATOM   2422 N NE1 . TRP B 1 69  ? -18.318 -33.369 17.041  1.000 16.311 0 104 TRP B NE1 1 ? 
ATOM   2423 C CE2 . TRP B 1 69  ? -18.723 -34.497 16.378  1.000 15.318 0 104 TRP B CE2 1 ? 
ATOM   2424 C CE3 . TRP B 1 69  ? -19.379 -36.762 16.926  1.000 15.408 0 104 TRP B CE3 1 ? 
ATOM   2425 C CZ2 . TRP B 1 69  ? -18.918 -34.724 15.011  1.000 15.732 0 104 TRP B CZ2 1 ? 
ATOM   2426 C CZ3 . TRP B 1 69  ? -19.562 -36.981 15.576  1.000 15.366 0 104 TRP B CZ3 1 ? 
ATOM   2427 C CH2 . TRP B 1 69  ? -19.319 -35.984 14.630  1.000 14.412 0 104 TRP B CH2 1 ? 
ATOM   2428 N N   . LEU B 1 70  ? -16.160 -36.609 18.294  1.000 17.500 0 105 LEU B N   1 ? 
ATOM   2429 C CA  . LEU B 1 70  ? -15.687 -37.327 17.118  1.000 18.170 0 105 LEU B CA  1 ? 
ATOM   2430 C C   . LEU B 1 70  ? -14.479 -38.204 17.467  1.000 18.060 0 105 LEU B C   1 ? 
ATOM   2431 O O   . LEU B 1 70  ? -14.296 -39.282 16.895  1.000 17.875 0 105 LEU B O   1 ? 
ATOM   2432 C CB  . LEU B 1 70  ? -15.376 -36.310 16.014  1.000 16.944 0 105 LEU B CB  1 ? 
ATOM   2433 C CG  . LEU B 1 70  ? -14.920 -36.871 14.667  1.000 18.898 0 105 LEU B CG  1 ? 
ATOM   2434 C CD1 . LEU B 1 70  ? -15.941 -37.820 14.076  1.000 18.951 0 105 LEU B CD1 1 ? 
ATOM   2435 C CD2 . LEU B 1 70  ? -14.605 -35.749 13.677  1.000 19.363 0 105 LEU B CD2 1 ? 
ATOM   2436 N N   . GLY B 1 71  ? -13.606 -37.711 18.354  1.000 19.641 0 106 GLY B N   1 ? 
ATOM   2437 C CA  . GLY B 1 71  ? -12.514 -38.523 18.887  1.000 18.730 0 106 GLY B CA  1 ? 
ATOM   2438 C C   . GLY B 1 71  ? -13.041 -39.832 19.474  1.000 18.534 0 106 GLY B C   1 ? 
ATOM   2439 O O   . GLY B 1 71  ? -12.530 -40.916 19.187  1.000 16.293 0 106 GLY B O   1 ? 
ATOM   2440 N N   . LYS B 1 72  ? -14.096 -39.713 20.287  1.000 18.541 0 107 LYS B N   1 ? 
ATOM   2441 C CA  . LYS B 1 72  ? -14.671 -40.865 20.958  1.000 20.503 0 107 LYS B CA  1 ? 
ATOM   2442 C C   . LYS B 1 72  ? -15.344 -41.759 19.919  1.000 18.099 0 107 LYS B C   1 ? 
ATOM   2443 O O   . LYS B 1 72  ? -15.240 -42.979 19.969  1.000 17.100 0 107 LYS B O   1 ? 
ATOM   2444 C CB  . LYS B 1 72  ? -15.628 -40.367 22.043  1.000 24.333 0 107 LYS B CB  1 ? 
ATOM   2445 C CG  . LYS B 1 72  ? -16.244 -41.459 22.896  1.000 31.128 0 107 LYS B CG  1 ? 
ATOM   2446 C CD  . LYS B 1 72  ? -17.336 -40.946 23.820  1.000 38.336 0 107 LYS B CD  1 ? 
ATOM   2447 C CE  . LYS B 1 72  ? -18.337 -42.031 24.186  1.000 40.296 0 107 LYS B CE  1 ? 
ATOM   2448 N NZ  . LYS B 1 72  ? -17.654 -43.294 24.570  1.000 40.296 0 107 LYS B NZ  1 ? 
ATOM   2449 N N   . HIS B 1 73  ? -16.083 -41.141 18.992  1.000 18.426 0 108 HIS B N   1 ? 
ATOM   2450 C CA  . HIS B 1 73  ? -16.815 -41.894 17.987  1.000 17.219 0 108 HIS B CA  1 ? 
ATOM   2451 C C   . HIS B 1 73  ? -15.852 -42.743 17.147  1.000 17.216 0 108 HIS B C   1 ? 
ATOM   2452 O O   . HIS B 1 73  ? -16.059 -43.939 16.956  1.000 16.740 0 108 HIS B O   1 ? 
ATOM   2453 C CB  . HIS B 1 73  ? -17.670 -40.953 17.134  1.000 18.046 0 108 HIS B CB  1 ? 
ATOM   2454 C CG  . HIS B 1 73  ? -18.437 -41.742 16.151  1.000 17.544 0 108 HIS B CG  1 ? 
ATOM   2455 N ND1 . HIS B 1 73  ? -19.615 -42.380 16.464  1.000 17.609 0 108 HIS B ND1 1 ? 
ATOM   2456 C CD2 . HIS B 1 73  ? -18.127 -42.091 14.902  1.000 17.841 0 108 HIS B CD2 1 ? 
ATOM   2457 C CE1 . HIS B 1 73  ? -20.045 -43.019 15.389  1.000 18.847 0 108 HIS B CE1 1 ? 
ATOM   2458 N NE2 . HIS B 1 73  ? -19.145 -42.898 14.444  1.000 18.227 0 108 HIS B NE2 1 ? 
ATOM   2459 N N   . LEU B 1 74  ? -14.790 -42.120 16.632  1.000 18.662 0 109 LEU B N   1 ? 
ATOM   2460 C CA  . LEU B 1 74  ? -13.855 -42.819 15.761  1.000 18.615 0 109 LEU B CA  1 ? 
ATOM   2461 C C   . LEU B 1 74  ? -13.138 -43.914 16.540  1.000 18.387 0 109 LEU B C   1 ? 
ATOM   2462 O O   . LEU B 1 74  ? -12.989 -45.026 16.027  1.000 15.066 0 109 LEU B O   1 ? 
ATOM   2463 C CB  . LEU B 1 74  ? -12.873 -41.816 15.153  1.000 19.000 0 109 LEU B CB  1 ? 
ATOM   2464 C CG  . LEU B 1 74  ? -13.422 -40.938 14.030  1.000 19.352 0 109 LEU B CG  1 ? 
ATOM   2465 C CD1 . LEU B 1 74  ? -12.462 -39.808 13.721  1.000 19.419 0 109 LEU B CD1 1 ? 
ATOM   2466 C CD2 . LEU B 1 74  ? -13.686 -41.750 12.771  1.000 21.082 0 109 LEU B CD2 1 ? 
ATOM   2467 N N   . ALA B 1 75  ? -12.698 -43.606 17.774  1.000 16.527 0 110 ALA B N   1 ? 
ATOM   2468 C CA  . ALA B 1 75  ? -11.991 -44.602 18.568  1.000 16.263 0 110 ALA B CA  1 ? 
ATOM   2469 C C   . ALA B 1 75  ? -12.858 -45.837 18.778  1.000 16.001 0 110 ALA B C   1 ? 
ATOM   2470 O O   . ALA B 1 75  ? -12.329 -46.946 18.735  1.000 15.366 0 110 ALA B O   1 ? 
ATOM   2471 C CB  . ALA B 1 75  ? -11.541 -44.049 19.899  1.000 15.955 0 110 ALA B CB  1 ? 
ATOM   2472 N N   . SER B 1 76  ? -14.166 -45.633 19.026  1.000 16.794 0 111 SER B N   1 ? 
ATOM   2473 C CA  . SER B 1 76  ? -15.092 -46.732 19.300  1.000 16.702 0 111 SER B CA  1 ? 
ATOM   2474 C C   . SER B 1 76  ? -15.215 -47.677 18.096  1.000 17.841 0 111 SER B C   1 ? 
ATOM   2475 O O   . SER B 1 76  ? -15.604 -48.829 18.268  1.000 16.847 0 111 SER B O   1 ? 
ATOM   2476 C CB  . SER B 1 76  ? -16.461 -46.218 19.735  1.000 16.962 0 111 SER B CB  1 ? 
ATOM   2477 O OG  . SER B 1 76  ? -17.186 -45.671 18.630  1.000 16.496 0 111 SER B OG  1 ? 
ATOM   2478 N N   . HIS B 1 77  ? -14.872 -47.190 16.886  1.000 17.842 0 112 HIS B N   1 ? 
ATOM   2479 C CA  . HIS B 1 77  ? -14.900 -47.986 15.670  1.000 17.625 0 112 HIS B CA  1 ? 
ATOM   2480 C C   . HIS B 1 77  ? -13.564 -48.642 15.357  1.000 17.279 0 112 HIS B C   1 ? 
ATOM   2481 O O   . HIS B 1 77  ? -13.443 -49.287 14.328  1.000 17.481 0 112 HIS B O   1 ? 
ATOM   2482 C CB  . HIS B 1 77  ? -15.374 -47.154 14.477  1.000 17.674 0 112 HIS B CB  1 ? 
ATOM   2483 C CG  . HIS B 1 77  ? -16.846 -47.004 14.492  1.000 17.283 0 112 HIS B CG  1 ? 
ATOM   2484 N ND1 . HIS B 1 77  ? -17.643 -47.934 13.859  1.000 17.584 0 112 HIS B ND1 1 ? 
ATOM   2485 C CD2 . HIS B 1 77  ? -17.668 -46.121 15.091  1.000 17.097 0 112 HIS B CD2 1 ? 
ATOM   2486 C CE1 . HIS B 1 77  ? -18.916 -47.596 14.041  1.000 17.726 0 112 HIS B CE1 1 ? 
ATOM   2487 N NE2 . HIS B 1 77  ? -18.951 -46.499 14.805  1.000 17.016 0 112 HIS B NE2 1 ? 
ATOM   2488 N N   . GLY B 1 78  ? -12.575 -48.497 16.246  1.000 17.639 0 113 GLY B N   1 ? 
ATOM   2489 C CA  . GLY B 1 78  ? -11.307 -49.196 16.095  1.000 18.583 0 113 GLY B CA  1 ? 
ATOM   2490 C C   . GLY B 1 78  ? -10.215 -48.289 15.535  1.000 19.481 0 113 GLY B C   1 ? 
ATOM   2491 O O   . GLY B 1 78  ? -9.581  -48.632 14.543  1.000 17.501 0 113 GLY B O   1 ? 
ATOM   2492 N N   . PHE B 1 79  ? -9.994  -47.152 16.227  1.000 20.131 0 114 PHE B N   1 ? 
ATOM   2493 C CA  . PHE B 1 79  ? -8.880  -46.254 15.960  1.000 19.372 0 114 PHE B CA  1 ? 
ATOM   2494 C C   . PHE B 1 79  ? -8.320  -45.717 17.275  1.000 18.560 0 114 PHE B C   1 ? 
ATOM   2495 O O   . PHE B 1 79  ? -9.056  -45.559 18.247  1.000 17.445 0 114 PHE B O   1 ? 
ATOM   2496 C CB  . PHE B 1 79  ? -9.301  -45.102 15.040  1.000 18.027 0 114 PHE B CB  1 ? 
ATOM   2497 C CG  . PHE B 1 79  ? -9.765  -45.546 13.679  1.000 17.861 0 114 PHE B CG  1 ? 
ATOM   2498 C CD1 . PHE B 1 79  ? -8.856  -45.909 12.707  1.000 17.564 0 114 PHE B CD1 1 ? 
ATOM   2499 C CD2 . PHE B 1 79  ? -11.125 -45.665 13.395  1.000 17.540 0 114 PHE B CD2 1 ? 
ATOM   2500 C CE1 . PHE B 1 79  ? -9.293  -46.352 11.463  1.000 17.871 0 114 PHE B CE1 1 ? 
ATOM   2501 C CE2 . PHE B 1 79  ? -11.555 -46.126 12.162  1.000 17.681 0 114 PHE B CE2 1 ? 
ATOM   2502 C CZ  . PHE B 1 79  ? -10.638 -46.443 11.188  1.000 17.709 0 114 PHE B CZ  1 ? 
ATOM   2503 N N   . VAL B 1 80  ? -7.011  -45.414 17.261  1.000 17.618 0 115 VAL B N   1 ? 
ATOM   2504 C CA  . VAL B 1 80  ? -6.366  -44.574 18.269  1.000 18.296 0 115 VAL B CA  1 ? 
ATOM   2505 C C   . VAL B 1 80  ? -6.413  -43.129 17.779  1.000 17.447 0 115 VAL B C   1 ? 
ATOM   2506 O O   . VAL B 1 80  ? -5.825  -42.821 16.750  1.000 18.547 0 115 VAL B O   1 ? 
ATOM   2507 C CB  . VAL B 1 80  ? -4.901  -44.998 18.526  1.000 18.834 0 115 VAL B CB  1 ? 
ATOM   2508 C CG1 . VAL B 1 80  ? -4.236  -44.092 19.559  1.000 19.084 0 115 VAL B CG1 1 ? 
ATOM   2509 C CG2 . VAL B 1 80  ? -4.785  -46.458 18.936  1.000 18.831 0 115 VAL B CG2 1 ? 
ATOM   2510 N N   . VAL B 1 81  ? -7.097  -42.246 18.507  1.000 16.699 0 116 VAL B N   1 ? 
ATOM   2511 C CA  . VAL B 1 81  ? -7.357  -40.907 18.005  1.000 16.186 0 116 VAL B CA  1 ? 
ATOM   2512 C C   . VAL B 1 81  ? -6.790  -39.911 19.006  1.000 16.525 0 116 VAL B C   1 ? 
ATOM   2513 O O   . VAL B 1 81  ? -7.086  -39.978 20.203  1.000 16.341 0 116 VAL B O   1 ? 
ATOM   2514 C CB  . VAL B 1 81  ? -8.860  -40.671 17.763  1.000 16.619 0 116 VAL B CB  1 ? 
ATOM   2515 C CG1 . VAL B 1 81  ? -9.134  -39.297 17.143  1.000 16.126 0 116 VAL B CG1 1 ? 
ATOM   2516 C CG2 . VAL B 1 81  ? -9.451  -41.783 16.898  1.000 16.808 0 116 VAL B CG2 1 ? 
ATOM   2517 N N   . PHE B 1 82  ? -5.967  -38.997 18.485  1.000 15.921 0 117 PHE B N   1 ? 
ATOM   2518 C CA  . PHE B 1 82  ? -5.269  -38.024 19.297  1.000 14.869 0 117 PHE B CA  1 ? 
ATOM   2519 C C   . PHE B 1 82  ? -5.719  -36.637 18.872  1.000 14.954 0 117 PHE B C   1 ? 
ATOM   2520 O O   . PHE B 1 82  ? -5.420  -36.212 17.760  1.000 15.051 0 117 PHE B O   1 ? 
ATOM   2521 C CB  . PHE B 1 82  ? -3.762  -38.168 19.109  1.000 14.957 0 117 PHE B CB  1 ? 
ATOM   2522 C CG  . PHE B 1 82  ? -2.891  -37.398 20.068  1.000 14.603 0 117 PHE B CG  1 ? 
ATOM   2523 C CD1 . PHE B 1 82  ? -3.379  -36.858 21.240  1.000 14.965 0 117 PHE B CD1 1 ? 
ATOM   2524 C CD2 . PHE B 1 82  ? -1.554  -37.221 19.783  1.000 14.614 0 117 PHE B CD2 1 ? 
ATOM   2525 C CE1 . PHE B 1 82  ? -2.539  -36.183 22.121  1.000 15.603 0 117 PHE B CE1 1 ? 
ATOM   2526 C CE2 . PHE B 1 82  ? -0.715  -36.542 20.659  1.000 15.610 0 117 PHE B CE2 1 ? 
ATOM   2527 C CZ  . PHE B 1 82  ? -1.207  -36.030 21.834  1.000 15.013 0 117 PHE B CZ  1 ? 
ATOM   2528 N N   . VAL B 1 83  ? -6.431  -35.946 19.772  1.000 15.151 0 118 VAL B N   1 ? 
ATOM   2529 C CA  . VAL B 1 83  ? -6.962  -34.621 19.480  1.000 15.108 0 118 VAL B CA  1 ? 
ATOM   2530 C C   . VAL B 1 83  ? -6.085  -33.613 20.203  1.000 15.432 0 118 VAL B C   1 ? 
ATOM   2531 O O   . VAL B 1 83  ? -5.890  -33.719 21.419  1.000 15.295 0 118 VAL B O   1 ? 
ATOM   2532 C CB  . VAL B 1 83  ? -8.444  -34.473 19.890  1.000 15.721 0 118 VAL B CB  1 ? 
ATOM   2533 C CG1 . VAL B 1 83  ? -9.015  -33.124 19.447  1.000 15.975 0 118 VAL B CG1 1 ? 
ATOM   2534 C CG2 . VAL B 1 83  ? -9.288  -35.626 19.367  1.000 16.475 0 118 VAL B CG2 1 ? 
ATOM   2535 N N   . LEU B 1 84  ? -5.566  -32.640 19.439  1.000 15.380 0 119 LEU B N   1 ? 
ATOM   2536 C CA  . LEU B 1 84  ? -4.510  -31.762 19.924  1.000 15.657 0 119 LEU B CA  1 ? 
ATOM   2537 C C   . LEU B 1 84  ? -5.093  -30.447 20.422  1.000 16.365 0 119 LEU B C   1 ? 
ATOM   2538 O O   . LEU B 1 84  ? -6.194  -30.044 20.034  1.000 18.165 0 119 LEU B O   1 ? 
ATOM   2539 C CB  . LEU B 1 84  ? -3.518  -31.498 18.797  1.000 16.344 0 119 LEU B CB  1 ? 
ATOM   2540 C CG  . LEU B 1 84  ? -2.913  -32.742 18.149  1.000 16.197 0 119 LEU B CG  1 ? 
ATOM   2541 C CD1 . LEU B 1 84  ? -1.808  -32.318 17.220  1.000 17.615 0 119 LEU B CD1 1 ? 
ATOM   2542 C CD2 . LEU B 1 84  ? -2.370  -33.732 19.180  1.000 16.444 0 119 LEU B CD2 1 ? 
ATOM   2543 N N   . ASN B 1 85  ? -4.332  -29.799 21.314  1.000 16.147 0 120 ASN B N   1 ? 
ATOM   2544 C CA  . ASN B 1 85  ? -4.501  -28.396 21.630  1.000 16.188 0 120 ASN B CA  1 ? 
ATOM   2545 C C   . ASN B 1 85  ? -3.405  -27.636 20.882  1.000 17.421 0 120 ASN B C   1 ? 
ATOM   2546 O O   . ASN B 1 85  ? -2.342  -28.201 20.598  1.000 17.026 0 120 ASN B O   1 ? 
ATOM   2547 C CB  . ASN B 1 85  ? -4.424  -28.102 23.130  1.000 15.856 0 120 ASN B CB  1 ? 
ATOM   2548 C CG  . ASN B 1 85  ? -5.273  -29.003 23.999  1.000 16.775 0 120 ASN B CG  1 ? 
ATOM   2549 O OD1 . ASN B 1 85  ? -6.484  -29.044 23.823  1.000 17.088 0 120 ASN B OD1 1 ? 
ATOM   2550 N ND2 . ASN B 1 85  ? -4.669  -29.651 24.990  1.000 16.468 0 120 ASN B ND2 1 ? 
ATOM   2551 N N   . HIS B 1 86  ? -3.683  -26.358 20.603  1.000 17.897 0 121 HIS B N   1 ? 
ATOM   2552 C CA  . HIS B 1 86  ? -2.785  -25.475 19.867  1.000 19.049 0 121 HIS B CA  1 ? 
ATOM   2553 C C   . HIS B 1 86  ? -1.755  -24.838 20.789  1.000 19.378 0 121 HIS B C   1 ? 
ATOM   2554 O O   . HIS B 1 86  ? -1.995  -24.730 21.971  1.000 21.736 0 121 HIS B O   1 ? 
ATOM   2555 C CB  . HIS B 1 86  ? -3.575  -24.331 19.227  1.000 17.817 0 121 HIS B CB  1 ? 
ATOM   2556 C CG  . HIS B 1 86  ? -4.518  -24.807 18.173  1.000 18.780 0 121 HIS B CG  1 ? 
ATOM   2557 N ND1 . HIS B 1 86  ? -4.104  -25.543 17.076  1.000 17.576 0 121 HIS B ND1 1 ? 
ATOM   2558 C CD2 . HIS B 1 86  ? -5.861  -24.700 18.082  1.000 17.441 0 121 HIS B CD2 1 ? 
ATOM   2559 C CE1 . HIS B 1 86  ? -5.184  -25.839 16.347  1.000 19.626 0 121 HIS B CE1 1 ? 
ATOM   2560 N NE2 . HIS B 1 86  ? -6.258  -25.324 16.931  1.000 17.660 0 121 HIS B NE2 1 ? 
ATOM   2561 N N   . LEU B 1 87  ? -0.607  -24.436 20.244  1.000 19.515 0 122 LEU B N   1 ? 
ATOM   2562 C CA  . LEU B 1 87  ? 0.324   -23.572 20.951  1.000 18.852 0 122 LEU B CA  1 ? 
ATOM   2563 C C   . LEU B 1 87  ? -0.142  -22.137 20.788  1.000 18.458 0 122 LEU B C   1 ? 
ATOM   2564 O O   . LEU B 1 87  ? -0.646  -21.777 19.728  1.000 18.728 0 122 LEU B O   1 ? 
ATOM   2565 C CB  . LEU B 1 87  ? 1.717   -23.712 20.342  1.000 20.460 0 122 LEU B CB  1 ? 
ATOM   2566 C CG  . LEU B 1 87  ? 2.326   -25.110 20.383  1.000 20.919 0 122 LEU B CG  1 ? 
ATOM   2567 C CD1 . LEU B 1 87  ? 3.513   -25.177 19.464  1.000 21.951 0 122 LEU B CD1 1 ? 
ATOM   2568 C CD2 . LEU B 1 87  ? 2.731   -25.450 21.806  1.000 20.726 0 122 LEU B CD2 1 ? 
ATOM   2569 N N   . SER B 1 88  ? 0.044   -21.307 21.816  1.000 19.776 0 123 SER B N   1 ? 
ATOM   2570 C CA  . SER B 1 88  ? -0.470  -19.947 21.761  1.000 21.817 0 123 SER B CA  1 ? 
ATOM   2571 C C   . SER B 1 88  ? 0.197   -19.110 20.659  1.000 22.941 0 123 SER B C   1 ? 
ATOM   2572 O O   . SER B 1 88  ? -0.381  -18.127 20.212  1.000 24.515 0 123 SER B O   1 ? 
ATOM   2573 C CB  . SER B 1 88  ? -0.384  -19.285 23.115  1.000 23.430 0 123 SER B CB  1 ? 
ATOM   2574 O OG  . SER B 1 88  ? 0.937   -19.334 23.628  1.000 27.334 0 123 SER B OG  1 ? 
ATOM   2575 N N   . LYS B 1 89  ? 1.394   -19.482 20.194  1.000 22.776 0 124 LYS B N   1 ? 
ATOM   2576 C CA  . LYS B 1 89  ? 2.096   -18.742 19.149  1.000 24.829 0 124 LYS B CA  1 ? 
ATOM   2577 C C   . LYS B 1 89  ? 1.516   -19.019 17.756  1.000 22.484 0 124 LYS B C   1 ? 
ATOM   2578 O O   . LYS B 1 89  ? 1.748   -18.250 16.821  1.000 20.991 0 124 LYS B O   1 ? 
ATOM   2579 C CB  . LYS B 1 89  ? 3.598   -19.090 19.130  1.000 31.548 0 124 LYS B CB  1 ? 
ATOM   2580 C CG  . LYS B 1 89  ? 3.910   -20.596 19.083  1.000 39.469 0 124 LYS B CG  1 ? 
ATOM   2581 C CD  . LYS B 1 89  ? 5.122   -21.093 18.227  1.000 39.762 0 124 LYS B CD  1 ? 
ATOM   2582 C CE  . LYS B 1 89  ? 4.894   -22.447 17.563  1.000 39.077 0 124 LYS B CE  1 ? 
ATOM   2583 N NZ  . LYS B 1 89  ? 3.625   -22.508 16.743  1.000 36.676 0 124 LYS B NZ  1 ? 
ATOM   2584 N N   . THR B 1 90  ? 0.795   -20.131 17.590  1.000 20.159 0 125 THR B N   1 ? 
ATOM   2585 C CA  . THR B 1 90  ? 0.260   -20.521 16.294  1.000 19.808 0 125 THR B CA  1 ? 
ATOM   2586 C C   . THR B 1 90  ? -0.601  -19.372 15.766  1.000 20.537 0 125 THR B C   1 ? 
ATOM   2587 O O   . THR B 1 90  ? -1.319  -18.742 16.544  1.000 19.688 0 125 THR B O   1 ? 
ATOM   2588 C CB  . THR B 1 90  ? -0.522  -21.838 16.438  1.000 18.421 0 125 THR B CB  1 ? 
ATOM   2589 O OG1 . THR B 1 90  ? 0.466   -22.827 16.722  1.000 18.180 0 125 THR B OG1 1 ? 
ATOM   2590 C CG2 . THR B 1 90  ? -1.336  -22.211 15.215  1.000 18.340 0 125 THR B CG2 1 ? 
ATOM   2591 N N   . ASP B 1 91  ? -0.493  -19.078 14.458  1.000 21.012 0 126 ASP B N   1 ? 
ATOM   2592 C CA  . ASP B 1 91  ? -1.335  -18.053 13.855  1.000 22.244 0 126 ASP B CA  1 ? 
ATOM   2593 C C   . ASP B 1 91  ? -1.716  -18.344 12.408  1.000 20.939 0 126 ASP B C   1 ? 
ATOM   2594 O O   . ASP B 1 91  ? -2.281  -17.468 11.761  1.000 21.614 0 126 ASP B O   1 ? 
ATOM   2595 C CB  . ASP B 1 91  ? -0.702  -16.663 13.926  1.000 23.484 0 126 ASP B CB  1 ? 
ATOM   2596 C CG  . ASP B 1 91  ? 0.609   -16.451 13.183  1.000 25.508 0 126 ASP B CG  1 ? 
ATOM   2597 O OD1 . ASP B 1 91  ? 1.019   -17.321 12.385  1.000 26.251 0 126 ASP B OD1 1 ? 
ATOM   2598 O OD2 . ASP B 1 91  ? 1.213   -15.379 13.418  1.000 28.315 0 126 ASP B OD2 1 ? 
ATOM   2599 N N   . ASP B 1 92  ? -1.441  -19.558 11.917  1.000 19.526 0 127 ASP B N   1 ? 
ATOM   2600 C CA  . ASP B 1 92  ? -1.864  -19.967 10.586  1.000 18.850 0 127 ASP B CA  1 ? 
ATOM   2601 C C   . ASP B 1 92  ? -1.861  -21.492 10.466  1.000 16.816 0 127 ASP B C   1 ? 
ATOM   2602 O O   . ASP B 1 92  ? -1.409  -22.209 11.348  1.000 15.922 0 127 ASP B O   1 ? 
ATOM   2603 C CB  . ASP B 1 92  ? -1.018  -19.280 9.498   1.000 20.046 0 127 ASP B CB  1 ? 
ATOM   2604 C CG  . ASP B 1 92  ? 0.463   -19.602 9.529   1.000 20.174 0 127 ASP B CG  1 ? 
ATOM   2605 O OD1 . ASP B 1 92  ? 0.866   -20.618 10.131  1.000 20.471 0 127 ASP B OD1 1 ? 
ATOM   2606 O OD2 . ASP B 1 92  ? 1.197   -18.837 8.938   1.000 22.647 0 127 ASP B OD2 1 ? 
ATOM   2607 N N   . ALA B 1 93  ? -2.429  -21.975 9.355   1.000 17.613 0 128 ALA B N   1 ? 
ATOM   2608 C CA  . ALA B 1 93  ? -2.605  -23.405 9.114   1.000 17.595 0 128 ALA B CA  1 ? 
ATOM   2609 C C   . ALA B 1 93  ? -1.257  -24.110 8.990   1.000 17.843 0 128 ALA B C   1 ? 
ATOM   2610 O O   . ALA B 1 93  ? -1.156  -25.288 9.343   1.000 16.605 0 128 ALA B O   1 ? 
ATOM   2611 C CB  . ALA B 1 93  ? -3.422  -23.627 7.875   1.000 17.437 0 128 ALA B CB  1 ? 
ATOM   2612 N N   . ASP B 1 94  ? -0.225  -23.386 8.512   1.000 17.500 0 129 ASP B N   1 ? 
ATOM   2613 C CA  . ASP B 1 94  ? 1.123   -23.927 8.423   1.000 18.579 0 129 ASP B CA  1 ? 
ATOM   2614 C C   . ASP B 1 94  ? 1.637   -24.338 9.809   1.000 18.167 0 129 ASP B C   1 ? 
ATOM   2615 O O   . ASP B 1 94  ? 2.221   -25.417 9.966   1.000 15.636 0 129 ASP B O   1 ? 
ATOM   2616 C CB  . ASP B 1 94  ? 2.067   -22.940 7.748   1.000 19.691 0 129 ASP B CB  1 ? 
ATOM   2617 C CG  . ASP B 1 94  ? 1.467   -22.380 6.466   1.000 23.508 0 129 ASP B CG  1 ? 
ATOM   2618 O OD1 . ASP B 1 94  ? 0.501   -21.529 6.543   1.000 23.391 0 129 ASP B OD1 1 ? 
ATOM   2619 O OD2 . ASP B 1 94  ? 1.915   -22.828 5.392   1.000 26.661 0 129 ASP B OD2 1 ? 
ATOM   2620 N N   . ALA B 1 95  ? 1.405   -23.484 10.814  1.000 17.848 0 130 ALA B N   1 ? 
ATOM   2621 C CA  . ALA B 1 95  ? 1.814   -23.814 12.172  1.000 18.199 0 130 ALA B CA  1 ? 
ATOM   2622 C C   . ALA B 1 95  ? 0.973   -24.967 12.725  1.000 17.326 0 130 ALA B C   1 ? 
ATOM   2623 O O   . ALA B 1 95  ? 1.474   -25.746 13.531  1.000 18.897 0 130 ALA B O   1 ? 
ATOM   2624 C CB  . ALA B 1 95  ? 1.734   -22.597 13.062  1.000 18.204 0 130 ALA B CB  1 ? 
ATOM   2625 N N   . VAL B 1 96  ? -0.309  -25.057 12.323  1.000 16.672 0 131 VAL B N   1 ? 
ATOM   2626 C CA  . VAL B 1 96  ? -1.154  -26.165 12.754  1.000 15.081 0 131 VAL B CA  1 ? 
ATOM   2627 C C   . VAL B 1 96  ? -0.638  -27.481 12.175  1.000 15.960 0 131 VAL B C   1 ? 
ATOM   2628 O O   . VAL B 1 96  ? -0.659  -28.496 12.865  1.000 15.649 0 131 VAL B O   1 ? 
ATOM   2629 C CB  . VAL B 1 96  ? -2.642  -25.949 12.439  1.000 14.933 0 131 VAL B CB  1 ? 
ATOM   2630 C CG1 . VAL B 1 96  ? -3.468  -27.150 12.885  1.000 15.923 0 131 VAL B CG1 1 ? 
ATOM   2631 C CG2 . VAL B 1 96  ? -3.181  -24.671 13.074  1.000 14.301 0 131 VAL B CG2 1 ? 
ATOM   2632 N N   . ALA B 1 97  ? -0.165  -27.459 10.921  1.000 17.031 0 132 ALA B N   1 ? 
ATOM   2633 C CA  . ALA B 1 97  ? 0.444   -28.623 10.309  1.000 18.554 0 132 ALA B CA  1 ? 
ATOM   2634 C C   . ALA B 1 97  ? 1.670   -29.079 11.117  1.000 18.179 0 132 ALA B C   1 ? 
ATOM   2635 O O   . ALA B 1 97  ? 1.871   -30.274 11.300  1.000 17.609 0 132 ALA B O   1 ? 
ATOM   2636 C CB  . ALA B 1 97  ? 0.782   -28.319 8.868   1.000 19.920 0 132 ALA B CB  1 ? 
ATOM   2637 N N   . ASP B 1 98  ? 2.454   -28.121 11.645  1.000 18.602 0 133 ASP B N   1 ? 
ATOM   2638 C CA  . ASP B 1 98  ? 3.589   -28.443 12.502  1.000 18.861 0 133 ASP B CA  1 ? 
ATOM   2639 C C   . ASP B 1 98  ? 3.117   -29.111 13.803  1.000 17.405 0 133 ASP B C   1 ? 
ATOM   2640 O O   . ASP B 1 98  ? 3.767   -30.037 14.287  1.000 15.887 0 133 ASP B O   1 ? 
ATOM   2641 C CB  . ASP B 1 98  ? 4.419   -27.210 12.852  1.000 20.892 0 133 ASP B CB  1 ? 
ATOM   2642 C CG  . ASP B 1 98  ? 5.082   -26.535 11.664  1.000 23.978 0 133 ASP B CG  1 ? 
ATOM   2643 O OD1 . ASP B 1 98  ? 5.203   -27.185 10.624  1.000 25.291 0 133 ASP B OD1 1 ? 
ATOM   2644 O OD2 . ASP B 1 98  ? 5.435   -25.333 11.791  1.000 26.582 0 133 ASP B OD2 1 ? 
ATOM   2645 N N   . GLU B 1 99  ? 2.001   -28.626 14.373  1.000 16.136 0 134 GLU B N   1 ? 
ATOM   2646 C CA  . GLU B 1 99  ? 1.441   -29.198 15.597  1.000 15.928 0 134 GLU B CA  1 ? 
ATOM   2647 C C   . GLU B 1 99  ? 1.013   -30.647 15.360  1.000 14.790 0 134 GLU B C   1 ? 
ATOM   2648 O O   . GLU B 1 99  ? 1.342   -31.517 16.150  1.000 15.034 0 134 GLU B O   1 ? 
ATOM   2649 C CB  . GLU B 1 99  ? 0.236   -28.387 16.098  1.000 16.776 0 134 GLU B CB  1 ? 
ATOM   2650 C CG  . GLU B 1 99  ? 0.540   -26.964 16.555  1.000 17.480 0 134 GLU B CG  1 ? 
ATOM   2651 C CD  . GLU B 1 99  ? -0.703  -26.124 16.846  1.000 18.899 0 134 GLU B CD  1 ? 
ATOM   2652 O OE1 . GLU B 1 99  ? -1.816  -26.538 16.413  1.000 20.220 0 134 GLU B OE1 1 ? 
ATOM   2653 O OE2 . GLU B 1 99  ? -0.572  -25.066 17.515  1.000 18.260 0 134 GLU B OE2 1 ? 
ATOM   2654 N N   . LEU B 1 100 ? 0.283   -30.887 14.269  1.000 15.909 0 135 LEU B N   1 ? 
ATOM   2655 C CA  . LEU B 1 100 ? -0.121  -32.218 13.834  1.000 16.309 0 135 LEU B CA  1 ? 
ATOM   2656 C C   . LEU B 1 100 ? 1.078   -33.147 13.650  1.000 16.314 0 135 LEU B C   1 ? 
ATOM   2657 O O   . LEU B 1 100 ? 1.011   -34.294 14.088  1.000 16.882 0 135 LEU B O   1 ? 
ATOM   2658 C CB  . LEU B 1 100 ? -0.886  -32.097 12.518  1.000 16.840 0 135 LEU B CB  1 ? 
ATOM   2659 C CG  . LEU B 1 100 ? -2.315  -31.555 12.624  1.000 17.431 0 135 LEU B CG  1 ? 
ATOM   2660 C CD1 . LEU B 1 100 ? -2.856  -31.228 11.246  1.000 17.978 0 135 LEU B CD1 1 ? 
ATOM   2661 C CD2 . LEU B 1 100 ? -3.246  -32.548 13.308  1.000 17.766 0 135 LEU B CD2 1 ? 
ATOM   2662 N N   . ALA B 1 101 ? 2.148   -32.669 12.995  1.000 15.635 0 136 ALA B N   1 ? 
ATOM   2663 C CA  . ALA B 1 101 ? 3.342   -33.480 12.799  1.000 16.676 0 136 ALA B CA  1 ? 
ATOM   2664 C C   . ALA B 1 101 ? 3.945   -33.885 14.146  1.000 16.546 0 136 ALA B C   1 ? 
ATOM   2665 O O   . ALA B 1 101 ? 4.341   -35.037 14.327  1.000 16.353 0 136 ALA B O   1 ? 
ATOM   2666 C CB  . ALA B 1 101 ? 4.353   -32.744 11.955  1.000 18.222 0 136 ALA B CB  1 ? 
ATOM   2667 N N   . ALA B 1 102 ? 4.006   -32.934 15.093  1.000 16.838 0 137 ALA B N   1 ? 
ATOM   2668 C CA  . ALA B 1 102 ? 4.580   -33.202 16.405  1.000 16.278 0 137 ALA B CA  1 ? 
ATOM   2669 C C   . ALA B 1 102 ? 3.694   -34.170 17.190  1.000 16.189 0 137 ALA B C   1 ? 
ATOM   2670 O O   . ALA B 1 102 ? 4.187   -35.067 17.856  1.000 14.909 0 137 ALA B O   1 ? 
ATOM   2671 C CB  . ALA B 1 102 ? 4.787   -31.903 17.144  1.000 16.464 0 137 ALA B CB  1 ? 
ATOM   2672 N N   . GLY B 1 103 ? 2.371   -34.019 17.059  1.000 16.919 0 138 GLY B N   1 ? 
ATOM   2673 C CA  . GLY B 1 103 ? 1.417   -34.935 17.663  1.000 16.439 0 138 GLY B CA  1 ? 
ATOM   2674 C C   . GLY B 1 103 ? 1.536   -36.362 17.147  1.000 17.162 0 138 GLY B C   1 ? 
ATOM   2675 O O   . GLY B 1 103 ? 1.438   -37.305 17.931  1.000 16.704 0 138 GLY B O   1 ? 
ATOM   2676 N N   . LEU B 1 104 ? 1.689   -36.519 15.823  1.000 19.502 0 139 LEU B N   1 ? 
ATOM   2677 C CA  . LEU B 1 104 ? 1.893   -37.830 15.216  1.000 20.723 0 139 LEU B CA  1 ? 
ATOM   2678 C C   . LEU B 1 104 ? 3.129   -38.499 15.827  1.000 19.966 0 139 LEU B C   1 ? 
ATOM   2679 O O   . LEU B 1 104 ? 3.086   -39.664 16.227  1.000 18.435 0 139 LEU B O   1 ? 
ATOM   2680 C CB  . LEU B 1 104 ? 2.059   -37.699 13.693  1.000 20.895 0 139 LEU B CB  1 ? 
ATOM   2681 C CG  . LEU B 1 104 ? 0.777   -37.514 12.883  1.000 23.780 0 139 LEU B CG  1 ? 
ATOM   2682 C CD1 . LEU B 1 104 ? 1.071   -36.870 11.525  1.000 25.440 0 139 LEU B CD1 1 ? 
ATOM   2683 C CD2 . LEU B 1 104 ? 0.037   -38.837 12.679  1.000 22.233 0 139 LEU B CD2 1 ? 
ATOM   2684 N N   . GLU B 1 105 ? 4.235   -37.754 15.861  1.000 19.451 0 140 GLU B N   1 ? 
ATOM   2685 C CA  . GLU B 1 105 ? 5.484   -38.301 16.349  1.000 22.804 0 140 GLU B CA  1 ? 
ATOM   2686 C C   . GLU B 1 105 ? 5.364   -38.687 17.833  1.000 20.867 0 140 GLU B C   1 ? 
ATOM   2687 O O   . GLU B 1 105 ? 5.816   -39.761 18.228  1.000 18.224 0 140 GLU B O   1 ? 
ATOM   2688 C CB  . GLU B 1 105 ? 6.605   -37.298 16.066  1.000 26.339 0 140 GLU B CB  1 ? 
ATOM   2689 C CG  . GLU B 1 105 ? 7.992   -37.884 16.246  1.000 32.452 0 140 GLU B CG  1 ? 
ATOM   2690 C CD  . GLU B 1 105 ? 8.312   -39.144 15.440  1.000 38.268 0 140 GLU B CD  1 ? 
ATOM   2691 O OE1 . GLU B 1 105 ? 7.574   -39.489 14.458  1.000 39.791 0 140 GLU B OE1 1 ? 
ATOM   2692 O OE2 . GLU B 1 105 ? 9.297   -39.816 15.818  1.000 50.549 0 140 GLU B OE2 1 ? 
ATOM   2693 N N   . TYR B 1 106 ? 4.730   -37.828 18.650  1.000 20.018 0 141 TYR B N   1 ? 
ATOM   2694 C CA  . TYR B 1 106 ? 4.471   -38.168 20.046  1.000 18.914 0 141 TYR B CA  1 ? 
ATOM   2695 C C   . TYR B 1 106 ? 3.650   -39.452 20.150  1.000 16.580 0 141 TYR B C   1 ? 
ATOM   2696 O O   . TYR B 1 106 ? 3.972   -40.330 20.957  1.000 16.361 0 141 TYR B O   1 ? 
ATOM   2697 C CB  . TYR B 1 106 ? 3.765   -37.036 20.806  1.000 19.273 0 141 TYR B CB  1 ? 
ATOM   2698 C CG  . TYR B 1 106 ? 3.350   -37.420 22.208  1.000 19.837 0 141 TYR B CG  1 ? 
ATOM   2699 C CD1 . TYR B 1 106 ? 2.158   -38.081 22.443  1.000 20.613 0 141 TYR B CD1 1 ? 
ATOM   2700 C CD2 . TYR B 1 106 ? 4.200   -37.237 23.288  1.000 21.850 0 141 TYR B CD2 1 ? 
ATOM   2701 C CE1 . TYR B 1 106 ? 1.770   -38.448 23.722  1.000 21.820 0 141 TYR B CE1 1 ? 
ATOM   2702 C CE2 . TYR B 1 106 ? 3.841   -37.620 24.576  1.000 21.332 0 141 TYR B CE2 1 ? 
ATOM   2703 C CZ  . TYR B 1 106 ? 2.616   -38.228 24.796  1.000 22.973 0 141 TYR B CZ  1 ? 
ATOM   2704 O OH  . TYR B 1 106 ? 2.219   -38.636 26.056  1.000 23.698 0 141 TYR B OH  1 ? 
ATOM   2705 N N   . LEU B 1 107 ? 2.568   -39.552 19.375  1.000 16.388 0 142 LEU B N   1 ? 
ATOM   2706 C CA  . LEU B 1 107 ? 1.655   -40.688 19.493  1.000 16.952 0 142 LEU B CA  1 ? 
ATOM   2707 C C   . LEU B 1 107 ? 2.389   -42.006 19.207  1.000 18.869 0 142 LEU B C   1 ? 
ATOM   2708 O O   . LEU B 1 107 ? 2.192   -43.014 19.890  1.000 16.889 0 142 LEU B O   1 ? 
ATOM   2709 C CB  . LEU B 1 107 ? 0.478   -40.510 18.539  1.000 15.815 0 142 LEU B CB  1 ? 
ATOM   2710 C CG  . LEU B 1 107 ? -0.619  -41.569 18.607  1.000 17.388 0 142 LEU B CG  1 ? 
ATOM   2711 C CD1 . LEU B 1 107 ? -1.279  -41.600 19.984  1.000 17.526 0 142 LEU B CD1 1 ? 
ATOM   2712 C CD2 . LEU B 1 107 ? -1.671  -41.356 17.524  1.000 16.970 0 142 LEU B CD2 1 ? 
ATOM   2713 N N   . LYS B 1 108 ? 3.224   -41.975 18.169  1.000 20.013 0 143 LYS B N   1 ? 
ATOM   2714 C CA  . LYS B 1 108 ? 3.978   -43.135 17.720  1.000 22.829 0 143 LYS B CA  1 ? 
ATOM   2715 C C   . LYS B 1 108 ? 5.078   -43.540 18.711  1.000 23.561 0 143 LYS B C   1 ? 
ATOM   2716 O O   . LYS B 1 108 ? 5.258   -44.730 18.968  1.000 23.982 0 143 LYS B O   1 ? 
ATOM   2717 C CB  . LYS B 1 108 ? 4.553   -42.863 16.329  1.000 24.369 0 143 LYS B CB  1 ? 
ATOM   2718 C CG  . LYS B 1 108 ? 3.508   -42.887 15.227  1.000 26.283 0 143 LYS B CG  1 ? 
ATOM   2719 C CD  . LYS B 1 108 ? 4.068   -42.787 13.824  1.000 31.890 0 143 LYS B CD  1 ? 
ATOM   2720 C CE  . LYS B 1 108 ? 4.765   -41.476 13.544  1.000 37.957 0 143 LYS B CE  1 ? 
ATOM   2721 N NZ  . LYS B 1 108 ? 4.757   -41.165 12.090  1.000 44.337 0 143 LYS B NZ  1 ? 
ATOM   2722 N N   . THR B 1 109 ? 5.791   -42.573 19.301  1.000 22.464 0 144 THR B N   1 ? 
ATOM   2723 C CA  . THR B 1 109 ? 7.046   -42.903 19.956  1.000 24.152 0 144 THR B CA  1 ? 
ATOM   2724 C C   . THR B 1 109 ? 7.067   -42.597 21.459  1.000 24.633 0 144 THR B C   1 ? 
ATOM   2725 O O   . THR B 1 109 ? 7.890   -43.176 22.148  1.000 24.282 0 144 THR B O   1 ? 
ATOM   2726 C CB  . THR B 1 109 ? 8.212   -42.202 19.247  1.000 25.483 0 144 THR B CB  1 ? 
ATOM   2727 O OG1 . THR B 1 109 ? 8.074   -40.793 19.441  1.000 26.864 0 144 THR B OG1 1 ? 
ATOM   2728 C CG2 . THR B 1 109 ? 8.263   -42.520 17.770  1.000 26.392 0 144 THR B CG2 1 ? 
ATOM   2729 N N   . LYS B 1 110 ? 6.230   -41.687 21.984  1.000 22.594 0 145 LYS B N   1 ? 
ATOM   2730 C CA  . LYS B 1 110 ? 6.427   -41.225 23.355  1.000 22.942 0 145 LYS B CA  1 ? 
ATOM   2731 C C   . LYS B 1 110 ? 5.185   -41.399 24.222  1.000 22.255 0 145 LYS B C   1 ? 
ATOM   2732 O O   . LYS B 1 110 ? 5.257   -41.130 25.421  1.000 18.904 0 145 LYS B O   1 ? 
ATOM   2733 C CB  . LYS B 1 110 ? 6.794   -39.737 23.419  1.000 27.675 0 145 LYS B CB  1 ? 
ATOM   2734 C CG  . LYS B 1 110 ? 7.941   -39.277 22.531  1.000 31.478 0 145 LYS B CG  1 ? 
ATOM   2735 C CD  . LYS B 1 110 ? 8.068   -37.757 22.427  1.000 37.824 0 145 LYS B CD  1 ? 
ATOM   2736 C CE  . LYS B 1 110 ? 8.120   -37.230 20.998  1.000 43.321 0 145 LYS B CE  1 ? 
ATOM   2737 N NZ  . LYS B 1 110 ? 9.435   -37.460 20.346  1.000 48.858 0 145 LYS B NZ  1 ? 
ATOM   2738 N N   . SER B 1 111 ? 4.060   -41.814 23.610  1.000 20.093 0 146 SER B N   1 ? 
ATOM   2739 C CA  . SER B 1 111 ? 2.798   -41.996 24.302  1.000 19.541 0 146 SER B CA  1 ? 
ATOM   2740 C C   . SER B 1 111 ? 2.923   -43.149 25.301  1.000 19.884 0 146 SER B C   1 ? 
ATOM   2741 O O   . SER B 1 111 ? 3.874   -43.930 25.223  1.000 20.022 0 146 SER B O   1 ? 
ATOM   2742 C CB  . SER B 1 111 ? 1.701   -42.239 23.297  1.000 19.378 0 146 SER B CB  1 ? 
ATOM   2743 O OG  . SER B 1 111 ? 1.973   -43.363 22.480  1.000 18.981 0 146 SER B OG  1 ? 
ATOM   2744 N N   . PRO B 1 112 ? 2.016   -43.284 26.296  1.000 20.015 0 147 PRO B N   1 ? 
ATOM   2745 C CA  . PRO B 1 112 ? 2.016   -44.444 27.201  1.000 19.817 0 147 PRO B CA  1 ? 
ATOM   2746 C C   . PRO B 1 112 ? 2.074   -45.787 26.493  1.000 18.990 0 147 PRO B C   1 ? 
ATOM   2747 O O   . PRO B 1 112 ? 1.529   -45.953 25.396  1.000 19.657 0 147 PRO B O   1 ? 
ATOM   2748 C CB  . PRO B 1 112 ? 0.688   -44.303 27.967  1.000 19.269 0 147 PRO B CB  1 ? 
ATOM   2749 C CG  . PRO B 1 112 ? 0.538   -42.822 28.020  1.000 20.302 0 147 PRO B CG  1 ? 
ATOM   2750 C CD  . PRO B 1 112 ? 0.924   -42.357 26.621  1.000 19.235 0 147 PRO B CD  1 ? 
ATOM   2751 N N   . ALA B 1 113 ? 2.744   -46.731 27.146  1.000 20.177 0 148 ALA B N   1 ? 
ATOM   2752 C CA  . ALA B 1 113 ? 2.878   -48.099 26.652  1.000 21.250 0 148 ALA B CA  1 ? 
ATOM   2753 C C   . ALA B 1 113 ? 1.523   -48.664 26.244  1.000 21.010 0 148 ALA B C   1 ? 
ATOM   2754 O O   . ALA B 1 113 ? 1.407   -49.332 25.221  1.000 21.337 0 148 ALA B O   1 ? 
ATOM   2755 C CB  . ALA B 1 113 ? 3.510   -48.981 27.722  1.000 20.565 0 148 ALA B CB  1 ? 
ATOM   2756 N N   . GLU B 1 114 ? 0.503   -48.407 27.062  1.000 23.006 0 149 GLU B N   1 ? 
ATOM   2757 C CA  . GLU B 1 114 ? -0.832  -48.934 26.793  1.000 25.423 0 149 GLU B CA  1 ? 
ATOM   2758 C C   . GLU B 1 114 ? -1.394  -48.373 25.480  1.000 24.066 0 149 GLU B C   1 ? 
ATOM   2759 O O   . GLU B 1 114 ? -2.123  -49.070 24.779  1.000 23.669 0 149 GLU B O   1 ? 
ATOM   2760 C CB  . GLU B 1 114 ? -1.763  -48.710 27.989  1.000 28.617 0 149 GLU B CB  1 ? 
ATOM   2761 C CG  . GLU B 1 114 ? -1.593  -47.371 28.744  1.000 37.222 0 149 GLU B CG  1 ? 
ATOM   2762 C CD  . GLU B 1 114 ? -0.560  -47.204 29.881  1.000 40.547 0 149 GLU B CD  1 ? 
ATOM   2763 O OE1 . GLU B 1 114 ? 0.655   -47.493 29.666  1.000 31.660 0 149 GLU B OE1 1 ? 
ATOM   2764 O OE2 . GLU B 1 114 ? -0.964  -46.704 31.000  1.000 39.698 0 149 GLU B OE2 1 ? 
ATOM   2765 N N   . VAL B 1 115 ? -1.056  -47.118 25.144  1.000 21.346 0 150 VAL B N   1 ? 
ATOM   2766 C CA  . VAL B 1 115 ? -1.499  -46.496 23.905  1.000 18.739 0 150 VAL B CA  1 ? 
ATOM   2767 C C   . VAL B 1 115 ? -0.737  -47.111 22.729  1.000 18.141 0 150 VAL B C   1 ? 
ATOM   2768 O O   . VAL B 1 115 ? -1.339  -47.503 21.728  1.000 15.461 0 150 VAL B O   1 ? 
ATOM   2769 C CB  . VAL B 1 115 ? -1.350  -44.962 23.942  1.000 17.568 0 150 VAL B CB  1 ? 
ATOM   2770 C CG1 . VAL B 1 115 ? -1.618  -44.322 22.588  1.000 17.863 0 150 VAL B CG1 1 ? 
ATOM   2771 C CG2 . VAL B 1 115 ? -2.265  -44.340 25.001  1.000 18.410 0 150 VAL B CG2 1 ? 
ATOM   2772 N N   . GLN B 1 116 ? 0.595   -47.185 22.853  1.000 17.862 0 151 GLN B N   1 ? 
ATOM   2773 C CA  . GLN B 1 116 ? 1.405   -47.760 21.793  1.000 18.623 0 151 GLN B CA  1 ? 
ATOM   2774 C C   . GLN B 1 116 ? 1.001   -49.214 21.512  1.000 18.385 0 151 GLN B C   1 ? 
ATOM   2775 O O   . GLN B 1 116 ? 1.020   -49.647 20.362  1.000 17.872 0 151 GLN B O   1 ? 
ATOM   2776 C CB  . GLN B 1 116 ? 2.888   -47.628 22.124  1.000 18.945 0 151 GLN B CB  1 ? 
ATOM   2777 C CG  . GLN B 1 116 ? 3.367   -46.184 22.176  1.000 19.029 0 151 GLN B CG  1 ? 
ATOM   2778 C CD  . GLN B 1 116 ? 4.867   -46.135 22.340  1.000 19.120 0 151 GLN B CD  1 ? 
ATOM   2779 O OE1 . GLN B 1 116 ? 5.572   -46.962 21.786  1.000 19.836 0 151 GLN B OE1 1 ? 
ATOM   2780 N NE2 . GLN B 1 116 ? 5.366   -45.220 23.152  1.000 20.000 0 151 GLN B NE2 1 ? 
ATOM   2781 N N   . ALA B 1 117 ? 0.608   -49.955 22.547  1.000 19.686 0 152 ALA B N   1 ? 
ATOM   2782 C CA  . ALA B 1 117 ? 0.172   -51.344 22.408  1.000 20.467 0 152 ALA B CA  1 ? 
ATOM   2783 C C   . ALA B 1 117 ? -1.063  -51.451 21.510  1.000 20.842 0 152 ALA B C   1 ? 
ATOM   2784 O O   . ALA B 1 117 ? -1.216  -52.433 20.792  1.000 22.287 0 152 ALA B O   1 ? 
ATOM   2785 C CB  . ALA B 1 117 ? -0.091  -51.952 23.783  1.000 19.943 0 152 ALA B CB  1 ? 
ATOM   2786 N N   . ARG B 1 118 ? -1.924  -50.425 21.505  1.000 20.924 0 153 ARG B N   1 ? 
ATOM   2787 C CA  . ARG B 1 118 ? -3.125  -50.459 20.692  1.000 19.835 0 153 ARG B CA  1 ? 
ATOM   2788 C C   . ARG B 1 118 ? -2.880  -49.845 19.315  1.000 19.352 0 153 ARG B C   1 ? 
ATOM   2789 O O   . ARG B 1 118 ? -3.794  -49.820 18.488  1.000 17.530 0 153 ARG B O   1 ? 
ATOM   2790 C CB  . ARG B 1 118 ? -4.261  -49.706 21.390  1.000 20.818 0 153 ARG B CB  1 ? 
ATOM   2791 C CG  . ARG B 1 118 ? -4.658  -50.287 22.740  1.000 20.966 0 153 ARG B CG  1 ? 
ATOM   2792 C CD  . ARG B 1 118 ? -5.489  -51.538 22.589  1.000 21.499 0 153 ARG B CD  1 ? 
ATOM   2793 N NE  . ARG B 1 118 ? -4.654  -52.701 22.383  1.000 22.217 0 153 ARG B NE  1 ? 
ATOM   2794 C CZ  . ARG B 1 118 ? -3.952  -53.295 23.331  1.000 22.615 0 153 ARG B CZ  1 ? 
ATOM   2795 N NH1 . ARG B 1 118 ? -4.038  -52.897 24.583  1.000 22.677 0 153 ARG B NH1 1 ? 
ATOM   2796 N NH2 . ARG B 1 118 ? -3.129  -54.268 23.009  1.000 23.369 0 153 ARG B NH2 1 ? 
ATOM   2797 N N   . LEU B 1 119 ? -1.676  -49.337 19.059  1.000 18.713 0 154 LEU B N   1 ? 
ATOM   2798 C CA  . LEU B 1 119 ? -1.427  -48.549 17.861  1.000 18.488 0 154 LEU B CA  1 ? 
ATOM   2799 C C   . LEU B 1 119 ? -0.685  -49.370 16.812  1.000 21.084 0 154 LEU B C   1 ? 
ATOM   2800 O O   . LEU B 1 119 ? 0.363   -49.974 17.080  1.000 21.204 0 154 LEU B O   1 ? 
ATOM   2801 C CB  . LEU B 1 119 ? -0.643  -47.289 18.218  1.000 18.398 0 154 LEU B CB  1 ? 
ATOM   2802 C CG  . LEU B 1 119 ? -0.299  -46.390 17.028  1.000 18.267 0 154 LEU B CG  1 ? 
ATOM   2803 C CD1 . LEU B 1 119 ? -1.539  -45.648 16.535  1.000 17.803 0 154 LEU B CD1 1 ? 
ATOM   2804 C CD2 . LEU B 1 119 ? 0.795   -45.397 17.392  1.000 19.515 0 154 LEU B CD2 1 ? 
ATOM   2805 N N   . ASP B 1 120 ? -1.220  -49.338 15.583  1.000 21.919 0 155 ASP B N   1 ? 
ATOM   2806 C CA  . ASP B 1 120 ? -0.483  -49.792 14.406  1.000 22.347 0 155 ASP B CA  1 ? 
ATOM   2807 C C   . ASP B 1 120 ? 0.091   -48.568 13.695  1.000 20.843 0 155 ASP B C   1 ? 
ATOM   2808 O O   . ASP B 1 120 ? -0.598  -47.929 12.903  1.000 18.169 0 155 ASP B O   1 ? 
ATOM   2809 C CB  . ASP B 1 120 ? -1.394  -50.594 13.483  1.000 23.691 0 155 ASP B CB  1 ? 
ATOM   2810 C CG  . ASP B 1 120 ? -0.733  -51.052 12.192  1.000 28.585 0 155 ASP B CG  1 ? 
ATOM   2811 O OD1 . ASP B 1 120 ? 0.453   -50.696 11.964  1.000 25.773 0 155 ASP B OD1 1 ? 
ATOM   2812 O OD2 . ASP B 1 120 ? -1.413  -51.784 11.428  1.000 29.856 0 155 ASP B OD2 1 ? 
ATOM   2813 N N   . ALA B 1 121 ? 1.360   -48.262 13.977  1.000 20.366 0 156 ALA B N   1 ? 
ATOM   2814 C CA  . ALA B 1 121 ? 1.994   -47.028 13.536  1.000 20.964 0 156 ALA B CA  1 ? 
ATOM   2815 C C   . ALA B 1 121 ? 2.250   -47.018 12.034  1.000 20.739 0 156 ALA B C   1 ? 
ATOM   2816 O O   . ALA B 1 121 ? 2.653   -45.990 11.495  1.000 21.696 0 156 ALA B O   1 ? 
ATOM   2817 C CB  . ALA B 1 121 ? 3.278   -46.781 14.295  1.000 20.778 0 156 ALA B CB  1 ? 
ATOM   2818 N N   . SER B 1 122 ? 1.980   -48.130 11.350  1.000 21.846 0 157 SER B N   1 ? 
ATOM   2819 C CA  . SER B 1 122 ? 2.177   -48.198 9.913   1.000 23.337 0 157 SER B CA  1 ? 
ATOM   2820 C C   . SER B 1 122 ? 0.970   -47.619 9.174   1.000 23.427 0 157 SER B C   1 ? 
ATOM   2821 O O   . SER B 1 122 ? 1.026   -47.432 7.963   1.000 24.984 0 157 SER B O   1 ? 
ATOM   2822 C CB  . SER B 1 122 ? 2.461   -49.629 9.472   1.000 23.227 0 157 SER B CB  1 ? 
ATOM   2823 O OG  . SER B 1 122 ? 1.262   -50.384 9.442   1.000 23.155 0 157 SER B OG  1 ? 
ATOM   2824 N N   . ARG B 1 123 ? -0.128  -47.355 9.900   1.000 21.415 0 158 ARG B N   1 ? 
ATOM   2825 C CA  . ARG B 1 123 ? -1.368  -46.907 9.296   1.000 21.044 0 158 ARG B CA  1 ? 
ATOM   2826 C C   . ARG B 1 123 ? -1.856  -45.672 10.051  1.000 21.644 0 158 ARG B C   1 ? 
ATOM   2827 O O   . ARG B 1 123 ? -2.372  -45.804 11.170  1.000 20.587 0 158 ARG B O   1 ? 
ATOM   2828 C CB  . ARG B 1 123 ? -2.380  -48.047 9.329   1.000 21.859 0 158 ARG B CB  1 ? 
ATOM   2829 C CG  . ARG B 1 123 ? -2.040  -49.214 8.406   1.000 25.502 0 158 ARG B CG  1 ? 
ATOM   2830 C CD  . ARG B 1 123 ? -2.873  -50.439 8.741   1.000 30.822 0 158 ARG B CD  1 ? 
ATOM   2831 N NE  . ARG B 1 123 ? -2.653  -51.548 7.809   1.000 37.354 0 158 ARG B NE  1 ? 
ATOM   2832 C CZ  . ARG B 1 123 ? -3.095  -51.604 6.548   1.000 39.418 0 158 ARG B CZ  1 ? 
ATOM   2833 N NH1 . ARG B 1 123 ? -3.981  -50.744 6.068   1.000 36.594 0 158 ARG B NH1 1 ? 
ATOM   2834 N NH2 . ARG B 1 123 ? -2.676  -52.580 5.774   1.000 39.828 0 158 ARG B NH2 1 ? 
ATOM   2835 N N   . MET B 1 124 ? -1.621  -44.478 9.475   1.000 20.276 0 159 MET B N   1 ? 
ATOM   2836 C CA  . MET B 1 124 ? -1.853  -43.226 10.189  1.000 19.833 0 159 MET B CA  1 ? 
ATOM   2837 C C   . MET B 1 124 ? -2.622  -42.261 9.286   1.000 19.456 0 159 MET B C   1 ? 
ATOM   2838 O O   . MET B 1 124 ? -2.332  -42.146 8.094   1.000 15.952 0 159 MET B O   1 ? 
ATOM   2839 C CB  . MET B 1 124 ? -0.552  -42.544 10.624  1.000 19.688 0 159 MET B CB  1 ? 
ATOM   2840 C CG  . MET B 1 124 ? 0.355   -43.404 11.494  1.000 20.967 0 159 MET B CG  1 ? 
ATOM   2841 S SD  . MET B 1 124 ? -0.346  -43.876 13.097  1.000 21.471 0 159 MET B SD  1 ? 
ATOM   2842 C CE  . MET B 1 124 ? -0.252  -42.301 13.948  1.000 21.868 0 159 MET B CE  1 ? 
ATOM   2843 N N   . GLY B 1 125 ? -3.603  -41.573 9.880   1.000 18.625 0 160 GLY B N   1 ? 
ATOM   2844 C CA  . GLY B 1 125 ? -4.357  -40.530 9.191   1.000 19.351 0 160 GLY B CA  1 ? 
ATOM   2845 C C   . GLY B 1 125 ? -4.431  -39.243 10.008  1.000 18.462 0 160 GLY B C   1 ? 
ATOM   2846 O O   . GLY B 1 125 ? -4.009  -39.206 11.164  1.000 18.727 0 160 GLY B O   1 ? 
ATOM   2847 N N   . VAL B 1 126 ? -4.967  -38.198 9.367   1.000 18.269 0 161 VAL B N   1 ? 
ATOM   2848 C CA  A VAL B 1 126 ? -5.114  -36.886 9.977   0.500 17.020 0 161 VAL B CA  1 ? 
ATOM   2849 C CA  B VAL B 1 126 ? -5.108  -36.887 9.972   0.500 17.893 0 161 VAL B CA  1 ? 
ATOM   2850 C C   . VAL B 1 126 ? -6.508  -36.344 9.675   1.000 16.513 0 161 VAL B C   1 ? 
ATOM   2851 O O   . VAL B 1 126 ? -7.080  -36.630 8.621   1.000 15.266 0 161 VAL B O   1 ? 
ATOM   2852 C CB  A VAL B 1 126 ? -4.054  -35.872 9.492   0.500 16.377 0 161 VAL B CB  1 ? 
ATOM   2853 C CB  B VAL B 1 126 ? -4.005  -35.948 9.441   0.500 18.390 0 161 VAL B CB  1 ? 
ATOM   2854 C CG1 A VAL B 1 126 ? -2.747  -36.022 10.256  0.500 16.811 0 161 VAL B CG1 1 ? 
ATOM   2855 C CG1 B VAL B 1 126 ? -4.074  -34.557 10.056  0.500 18.411 0 161 VAL B CG1 1 ? 
ATOM   2856 C CG2 A VAL B 1 126 ? -3.853  -35.902 7.980   0.500 15.218 0 161 VAL B CG2 1 ? 
ATOM   2857 C CG2 B VAL B 1 126 ? -2.626  -36.555 9.654   0.500 19.526 0 161 VAL B CG2 1 ? 
ATOM   2858 N N   . ALA B 1 127 ? -7.019  -35.529 10.612  1.000 16.958 0 162 ALA B N   1 ? 
ATOM   2859 C CA  . ALA B 1 127 ? -8.244  -34.764 10.424  1.000 17.300 0 162 ALA B CA  1 ? 
ATOM   2860 C C   . ALA B 1 127 ? -8.116  -33.426 11.152  1.000 17.225 0 162 ALA B C   1 ? 
ATOM   2861 O O   . ALA B 1 127 ? -7.240  -33.244 12.004  1.000 16.578 0 162 ALA B O   1 ? 
ATOM   2862 C CB  . ALA B 1 127 ? -9.436  -35.546 10.918  1.000 18.521 0 162 ALA B CB  1 ? 
ATOM   2863 N N   . GLY B 1 128 ? -8.977  -32.472 10.783  1.000 16.351 0 163 GLY B N   1 ? 
ATOM   2864 C CA  . GLY B 1 128 ? -8.958  -31.179 11.427  1.000 16.355 0 163 GLY B CA  1 ? 
ATOM   2865 C C   . GLY B 1 128 ? -10.139 -30.307 11.023  1.000 16.413 0 163 GLY B C   1 ? 
ATOM   2866 O O   . GLY B 1 128 ? -10.693 -30.470 9.935   1.000 16.539 0 163 GLY B O   1 ? 
ATOM   2867 N N   . HIS B 1 129 ? -10.473 -29.361 11.913  1.000 17.007 0 164 HIS B N   1 ? 
ATOM   2868 C CA  . HIS B 1 129 ? -11.574 -28.443 11.707  1.000 16.770 0 164 HIS B CA  1 ? 
ATOM   2869 C C   . HIS B 1 129 ? -11.056 -27.038 11.397  1.000 15.983 0 164 HIS B C   1 ? 
ATOM   2870 O O   . HIS B 1 129 ? -10.174 -26.535 12.097  1.000 16.325 0 164 HIS B O   1 ? 
ATOM   2871 C CB  . HIS B 1 129 ? -12.450 -28.428 12.957  1.000 17.085 0 164 HIS B CB  1 ? 
ATOM   2872 C CG  . HIS B 1 129 ? -13.638 -27.547 12.816  1.000 16.734 0 164 HIS B CG  1 ? 
ATOM   2873 N ND1 . HIS B 1 129 ? -14.138 -26.800 13.859  1.000 16.475 0 164 HIS B ND1 1 ? 
ATOM   2874 C CD2 . HIS B 1 129 ? -14.402 -27.293 11.742  1.000 16.766 0 164 HIS B CD2 1 ? 
ATOM   2875 C CE1 . HIS B 1 129 ? -15.192 -26.113 13.414  1.000 17.145 0 164 HIS B CE1 1 ? 
ATOM   2876 N NE2 . HIS B 1 129 ? -15.371 -26.394 12.123  1.000 17.910 0 164 HIS B NE2 1 ? 
ATOM   2877 N N   . SER B 1 130 ? -11.641 -26.389 10.371  1.000 14.938 0 165 SER B N   1 ? 
ATOM   2878 C CA  . SER B 1 130 ? -11.467 -24.952 10.161  1.000 14.210 0 165 SER B CA  1 ? 
ATOM   2879 C C   . SER B 1 130 ? -9.996  -24.697 9.829   1.000 14.256 0 165 SER B C   1 ? 
ATOM   2880 O O   . SER B 1 130 ? -9.482  -25.288 8.880   1.000 16.115 0 165 SER B O   1 ? 
ATOM   2881 C CB  . SER B 1 130 ? -12.008 -24.174 11.362  1.000 13.341 0 165 SER B CB  1 ? 
ATOM   2882 O OG  . SER B 1 130 ? -12.046 -22.772 11.136  1.000 12.724 0 165 SER B OG  1 ? 
ATOM   2883 N N   . MET B 1 131 ? -9.281  -23.868 10.597  1.000 15.173 0 166 MET B N   1 ? 
ATOM   2884 C CA  . MET B 1 131 ? -7.853  -23.710 10.350  1.000 14.868 0 166 MET B CA  1 ? 
ATOM   2885 C C   . MET B 1 131 ? -7.140  -25.057 10.544  1.000 15.119 0 166 MET B C   1 ? 
ATOM   2886 O O   . MET B 1 131 ? -6.143  -25.339 9.881   1.000 15.648 0 166 MET B O   1 ? 
ATOM   2887 C CB  . MET B 1 131 ? -7.237  -22.647 11.262  1.000 16.444 0 166 MET B CB  1 ? 
ATOM   2888 C CG  . MET B 1 131 ? -5.743  -22.357 11.000  1.000 17.208 0 166 MET B CG  1 ? 
ATOM   2889 S SD  . MET B 1 131 ? -5.012  -21.178 12.187  1.000 18.773 0 166 MET B SD  1 ? 
ATOM   2890 C CE  . MET B 1 131 ? -5.820  -19.642 11.751  1.000 18.701 0 166 MET B CE  1 ? 
ATOM   2891 N N   . GLY B 1 132 ? -7.676  -25.914 11.426  1.000 14.926 0 167 GLY B N   1 ? 
ATOM   2892 C CA  . GLY B 1 132 ? -7.186  -27.273 11.588  1.000 15.459 0 167 GLY B CA  1 ? 
ATOM   2893 C C   . GLY B 1 132 ? -7.323  -28.139 10.335  1.000 15.514 0 167 GLY B C   1 ? 
ATOM   2894 O O   . GLY B 1 132 ? -6.492  -29.015 10.108  1.000 15.882 0 167 GLY B O   1 ? 
ATOM   2895 N N   . GLY B 1 133 ? -8.349  -27.875 9.522   1.000 15.887 0 168 GLY B N   1 ? 
ATOM   2896 C CA  . GLY B 1 133 ? -8.538  -28.531 8.235   1.000 15.332 0 168 GLY B CA  1 ? 
ATOM   2897 C C   . GLY B 1 133 ? -7.566  -28.018 7.187   1.000 15.894 0 168 GLY B C   1 ? 
ATOM   2898 O O   . GLY B 1 133 ? -7.078  -28.775 6.356   1.000 15.499 0 168 GLY B O   1 ? 
ATOM   2899 N N   . GLY B 1 134 ? -7.276  -26.715 7.226   1.000 16.592 0 169 GLY B N   1 ? 
ATOM   2900 C CA  . GLY B 1 134 ? -6.172  -26.183 6.450   1.000 16.553 0 169 GLY B CA  1 ? 
ATOM   2901 C C   . GLY B 1 134 ? -4.859  -26.881 6.814   1.000 16.477 0 169 GLY B C   1 ? 
ATOM   2902 O O   . GLY B 1 134 ? -4.101  -27.281 5.938   1.000 16.567 0 169 GLY B O   1 ? 
ATOM   2903 N N   . GLY B 1 135 ? -4.623  -27.052 8.124   1.000 15.998 0 170 GLY B N   1 ? 
ATOM   2904 C CA  . GLY B 1 135 ? -3.435  -27.727 8.629   1.000 15.777 0 170 GLY B CA  1 ? 
ATOM   2905 C C   . GLY B 1 135 ? -3.320  -29.169 8.127   1.000 16.208 0 170 GLY B C   1 ? 
ATOM   2906 O O   . GLY B 1 135 ? -2.216  -29.644 7.852   1.000 16.259 0 170 GLY B O   1 ? 
ATOM   2907 N N   . THR B 1 136 ? -4.471  -29.854 8.054   1.000 15.566 0 171 THR B N   1 ? 
ATOM   2908 C CA  . THR B 1 136 ? -4.592  -31.214 7.567   1.000 16.738 0 171 THR B CA  1 ? 
ATOM   2909 C C   . THR B 1 136 ? -4.117  -31.313 6.115   1.000 16.333 0 171 THR B C   1 ? 
ATOM   2910 O O   . THR B 1 136 ? -3.384  -32.235 5.766   1.000 17.113 0 171 THR B O   1 ? 
ATOM   2911 C CB  . THR B 1 136 ? -6.048  -31.690 7.731   1.000 17.751 0 171 THR B CB  1 ? 
ATOM   2912 O OG1 . THR B 1 136 ? -6.290  -31.782 9.136   1.000 17.867 0 171 THR B OG1 1 ? 
ATOM   2913 C CG2 . THR B 1 136 ? -6.334  -33.018 7.081   1.000 18.515 0 171 THR B CG2 1 ? 
ATOM   2914 N N   . LEU B 1 137 ? -4.548  -30.360 5.278   1.000 15.817 0 172 LEU B N   1 ? 
ATOM   2915 C CA  . LEU B 1 137 ? -4.215  -30.365 3.876   1.000 17.057 0 172 LEU B CA  1 ? 
ATOM   2916 C C   . LEU B 1 137 ? -2.729  -30.071 3.703   1.000 18.517 0 172 LEU B C   1 ? 
ATOM   2917 O O   . LEU B 1 137 ? -2.085  -30.697 2.859   1.000 17.322 0 172 LEU B O   1 ? 
ATOM   2918 C CB  . LEU B 1 137 ? -5.099  -29.340 3.165   1.000 17.888 0 172 LEU B CB  1 ? 
ATOM   2919 C CG  . LEU B 1 137 ? -6.551  -29.774 2.929   1.000 18.851 0 172 LEU B CG  1 ? 
ATOM   2920 C CD1 . LEU B 1 137 ? -7.460  -28.567 2.622   1.000 18.006 0 172 LEU B CD1 1 ? 
ATOM   2921 C CD2 . LEU B 1 137 ? -6.632  -30.810 1.815   1.000 19.317 0 172 LEU B CD2 1 ? 
ATOM   2922 N N   . ILE B 1 138 ? -2.194  -29.124 4.493   1.000 18.388 0 173 ILE B N   1 ? 
ATOM   2923 C CA  . ILE B 1 138 ? -0.781  -28.795 4.390   1.000 19.548 0 173 ILE B CA  1 ? 
ATOM   2924 C C   . ILE B 1 138 ? 0.034   -30.019 4.785   1.000 20.695 0 173 ILE B C   1 ? 
ATOM   2925 O O   . ILE B 1 138 ? 0.999   -30.344 4.092   1.000 21.612 0 173 ILE B O   1 ? 
ATOM   2926 C CB  . ILE B 1 138 ? -0.403  -27.558 5.232   1.000 19.887 0 173 ILE B CB  1 ? 
ATOM   2927 C CG1 . ILE B 1 138 ? -1.061  -26.303 4.658   1.000 20.233 0 173 ILE B CG1 1 ? 
ATOM   2928 C CG2 . ILE B 1 138 ? 1.117   -27.401 5.345   1.000 19.541 0 173 ILE B CG2 1 ? 
ATOM   2929 C CD1 . ILE B 1 138 ? -0.980  -25.116 5.569   1.000 20.280 0 173 ILE B CD1 1 ? 
ATOM   2930 N N   . LEU B 1 139 ? -0.363  -30.711 5.869   1.000 19.280 0 174 LEU B N   1 ? 
ATOM   2931 C CA  . LEU B 1 139 ? 0.415   -31.843 6.338   1.000 19.263 0 174 LEU B CA  1 ? 
ATOM   2932 C C   . LEU B 1 139 ? 0.327   -32.991 5.322   1.000 18.606 0 174 LEU B C   1 ? 
ATOM   2933 O O   . LEU B 1 139 ? 1.324   -33.650 5.059   1.000 18.862 0 174 LEU B O   1 ? 
ATOM   2934 C CB  . LEU B 1 139 ? -0.041  -32.276 7.741   1.000 19.490 0 174 LEU B CB  1 ? 
ATOM   2935 C CG  . LEU B 1 139 ? 0.836   -33.361 8.373   1.000 21.337 0 174 LEU B CG  1 ? 
ATOM   2936 C CD1 . LEU B 1 139 ? 2.280   -32.876 8.546   1.000 21.899 0 174 LEU B CD1 1 ? 
ATOM   2937 C CD2 . LEU B 1 139 ? 0.275   -33.857 9.706   1.000 22.300 0 174 LEU B CD2 1 ? 
ATOM   2938 N N   . ALA B 1 140 ? -0.849  -33.232 4.736   1.000 17.817 0 175 ALA B N   1 ? 
ATOM   2939 C CA  . ALA B 1 140 ? -0.977  -34.279 3.733   1.000 18.112 0 175 ALA B CA  1 ? 
ATOM   2940 C C   . ALA B 1 140 ? -0.014  -34.034 2.565   1.000 19.309 0 175 ALA B C   1 ? 
ATOM   2941 O O   . ALA B 1 140 ? 0.518   -34.971 1.987   1.000 19.013 0 175 ALA B O   1 ? 
ATOM   2942 C CB  . ALA B 1 140 ? -2.393  -34.345 3.265   1.000 17.550 0 175 ALA B CB  1 ? 
ATOM   2943 N N   . GLU B 1 141 ? 0.227   -32.762 2.223   1.000 21.106 0 176 GLU B N   1 ? 
ATOM   2944 C CA  . GLU B 1 141 ? 1.158   -32.426 1.157   1.000 23.079 0 176 GLU B CA  1 ? 
ATOM   2945 C C   . GLU B 1 141 ? 2.595   -32.686 1.605   1.000 23.940 0 176 GLU B C   1 ? 
ATOM   2946 O O   . GLU B 1 141 ? 3.389   -33.186 0.817   1.000 23.685 0 176 GLU B O   1 ? 
ATOM   2947 C CB  . GLU B 1 141 ? 0.954   -30.983 0.696   1.000 24.563 0 176 GLU B CB  1 ? 
ATOM   2948 C CG  . GLU B 1 141 ? 1.952   -30.556 -0.356  1.000 26.603 0 176 GLU B CG  1 ? 
ATOM   2949 C CD  . GLU B 1 141 ? 1.770   -29.116 -0.758  1.000 29.129 0 176 GLU B CD  1 ? 
ATOM   2950 O OE1 . GLU B 1 141 ? 2.135   -28.273 0.054   1.000 35.094 0 176 GLU B OE1 1 ? 
ATOM   2951 O OE2 . GLU B 1 141 ? 1.188   -28.861 -1.822  1.000 28.716 0 176 GLU B OE2 1 ? 
ATOM   2952 N N   . ARG B 1 142 ? 2.919   -32.383 2.872   1.000 24.026 0 177 ARG B N   1 ? 
ATOM   2953 C CA  . ARG B 1 142 ? 4.266   -32.586 3.384   1.000 24.402 0 177 ARG B CA  1 ? 
ATOM   2954 C C   . ARG B 1 142 ? 4.585   -34.056 3.657   1.000 24.728 0 177 ARG B C   1 ? 
ATOM   2955 O O   . ARG B 1 142 ? 5.739   -34.455 3.502   1.000 23.936 0 177 ARG B O   1 ? 
ATOM   2956 C CB  . ARG B 1 142 ? 4.474   -31.880 4.720   1.000 24.803 0 177 ARG B CB  1 ? 
ATOM   2957 C CG  . ARG B 1 142 ? 4.392   -30.364 4.661   1.000 23.842 0 177 ARG B CG  1 ? 
ATOM   2958 C CD  . ARG B 1 142 ? 4.641   -29.920 6.087   1.000 24.159 0 177 ARG B CD  1 ? 
ATOM   2959 N NE  . ARG B 1 142 ? 4.514   -28.496 6.286   1.000 24.410 0 177 ARG B NE  1 ? 
ATOM   2960 C CZ  . ARG B 1 142 ? 4.474   -27.931 7.488   1.000 24.745 0 177 ARG B CZ  1 ? 
ATOM   2961 N NH1 . ARG B 1 142 ? 4.564   -28.677 8.590   1.000 22.948 0 177 ARG B NH1 1 ? 
ATOM   2962 N NH2 . ARG B 1 142 ? 4.283   -26.626 7.558   1.000 24.391 0 177 ARG B NH2 1 ? 
ATOM   2963 N N   . ASP B 1 143 ? 3.589   -34.853 4.085   1.000 23.662 0 178 ASP B N   1 ? 
ATOM   2964 C CA  . ASP B 1 143 ? 3.857   -36.183 4.605   1.000 24.928 0 178 ASP B CA  1 ? 
ATOM   2965 C C   . ASP B 1 143 ? 3.029   -37.212 3.851   1.000 25.600 0 178 ASP B C   1 ? 
ATOM   2966 O O   . ASP B 1 143 ? 1.968   -37.635 4.307   1.000 25.326 0 178 ASP B O   1 ? 
ATOM   2967 C CB  . ASP B 1 143 ? 3.624   -36.267 6.117   1.000 25.315 0 178 ASP B CB  1 ? 
ATOM   2968 C CG  . ASP B 1 143 ? 3.999   -37.615 6.723   1.000 26.648 0 178 ASP B CG  1 ? 
ATOM   2969 O OD1 . ASP B 1 143 ? 4.353   -38.533 5.946   1.000 22.641 0 178 ASP B OD1 1 ? 
ATOM   2970 O OD2 . ASP B 1 143 ? 3.881   -37.761 7.968   1.000 27.031 0 178 ASP B OD2 1 ? 
ATOM   2971 N N   . PRO B 1 144 ? 3.515   -37.719 2.700   1.000 28.175 0 179 PRO B N   1 ? 
ATOM   2972 C CA  . PRO B 1 144 ? 2.773   -38.728 1.933   1.000 27.220 0 179 PRO B CA  1 ? 
ATOM   2973 C C   . PRO B 1 144 ? 2.764   -40.129 2.528   1.000 23.320 0 179 PRO B C   1 ? 
ATOM   2974 O O   . PRO B 1 144 ? 2.191   -41.024 1.931   1.000 24.231 0 179 PRO B O   1 ? 
ATOM   2975 C CB  . PRO B 1 144 ? 3.484   -38.755 0.573   1.000 29.476 0 179 PRO B CB  1 ? 
ATOM   2976 C CG  . PRO B 1 144 ? 4.882   -38.293 0.878   1.000 29.895 0 179 PRO B CG  1 ? 
ATOM   2977 C CD  . PRO B 1 144 ? 4.749   -37.300 2.017   1.000 30.013 0 179 PRO B CD  1 ? 
ATOM   2978 N N   . SER B 1 145 ? 3.356   -40.331 3.708   1.000 20.781 0 180 SER B N   1 ? 
ATOM   2979 C CA  . SER B 1 145 ? 3.220   -41.604 4.404   1.000 22.341 0 180 SER B CA  1 ? 
ATOM   2980 C C   . SER B 1 145 ? 1.835   -41.745 5.043   1.000 19.714 0 180 SER B C   1 ? 
ATOM   2981 O O   . SER B 1 145 ? 1.401   -42.848 5.327   1.000 18.304 0 180 SER B O   1 ? 
ATOM   2982 C CB  . SER B 1 145 ? 4.311   -41.784 5.438   1.000 23.582 0 180 SER B CB  1 ? 
ATOM   2983 O OG  . SER B 1 145 ? 4.066   -40.973 6.581   1.000 23.453 0 180 SER B OG  1 ? 
ATOM   2984 N N   . LEU B 1 146 ? 1.144   -40.622 5.265   1.000 19.400 0 181 LEU B N   1 ? 
ATOM   2985 C CA  . LEU B 1 146 ? -0.223  -40.624 5.759   1.000 19.343 0 181 LEU B CA  1 ? 
ATOM   2986 C C   . LEU B 1 146 ? -1.099  -41.394 4.778   1.000 20.429 0 181 LEU B C   1 ? 
ATOM   2987 O O   . LEU B 1 146 ? -0.913  -41.279 3.561   1.000 20.911 0 181 LEU B O   1 ? 
ATOM   2988 C CB  . LEU B 1 146 ? -0.711  -39.173 5.898   1.000 19.110 0 181 LEU B CB  1 ? 
ATOM   2989 C CG  . LEU B 1 146 ? -0.049  -38.383 7.033   1.000 19.726 0 181 LEU B CG  1 ? 
ATOM   2990 C CD1 . LEU B 1 146 ? -0.415  -36.911 7.006   1.000 20.369 0 181 LEU B CD1 1 ? 
ATOM   2991 C CD2 . LEU B 1 146 ? -0.417  -38.971 8.376   1.000 20.914 0 181 LEU B CD2 1 ? 
ATOM   2992 N N   . LYS B 1 147 ? -2.092  -42.134 5.297   1.000 18.657 0 182 LYS B N   1 ? 
ATOM   2993 C CA  . LYS B 1 147 ? -2.921  -42.930 4.405   1.000 21.684 0 182 LYS B CA  1 ? 
ATOM   2994 C C   . LYS B 1 147 ? -4.321  -42.333 4.191   1.000 20.377 0 182 LYS B C   1 ? 
ATOM   2995 O O   . LYS B 1 147 ? -5.073  -42.853 3.363   1.000 19.635 0 182 LYS B O   1 ? 
ATOM   2996 C CB  . LYS B 1 147 ? -2.984  -44.376 4.912   1.000 24.539 0 182 LYS B CB  1 ? 
ATOM   2997 C CG  . LYS B 1 147 ? -1.729  -45.216 4.676   1.000 26.264 0 182 LYS B CG  1 ? 
ATOM   2998 C CD  . LYS B 1 147 ? -2.041  -46.708 4.569   1.000 32.655 0 182 LYS B CD  1 ? 
ATOM   2999 C CE  . LYS B 1 147 ? -0.925  -47.664 4.945   1.000 36.751 0 182 LYS B CE  1 ? 
ATOM   3000 N NZ  . LYS B 1 147 ? 0.426   -47.055 4.859   1.000 38.160 0 182 LYS B NZ  1 ? 
ATOM   3001 N N   . ALA B 1 148 ? -4.672  -41.267 4.935   1.000 17.822 0 183 ALA B N   1 ? 
ATOM   3002 C CA  . ALA B 1 148 ? -5.945  -40.579 4.743   1.000 18.321 0 183 ALA B CA  1 ? 
ATOM   3003 C C   . ALA B 1 148 ? -5.947  -39.233 5.469   1.000 17.492 0 183 ALA B C   1 ? 
ATOM   3004 O O   . ALA B 1 148 ? -5.284  -39.086 6.490   1.000 20.999 0 183 ALA B O   1 ? 
ATOM   3005 C CB  . ALA B 1 148 ? -7.099  -41.428 5.212   1.000 18.065 0 183 ALA B CB  1 ? 
ATOM   3006 N N   . ALA B 1 149 ? -6.674  -38.269 4.890   1.000 17.007 0 184 ALA B N   1 ? 
ATOM   3007 C CA  . ALA B 1 149 ? -6.852  -36.924 5.411   1.000 16.915 0 184 ALA B CA  1 ? 
ATOM   3008 C C   . ALA B 1 149 ? -8.319  -36.483 5.305   1.000 17.647 0 184 ALA B C   1 ? 
ATOM   3009 O O   . ALA B 1 149 ? -8.938  -36.655 4.268   1.000 16.898 0 184 ALA B O   1 ? 
ATOM   3010 C CB  . ALA B 1 149 ? -5.951  -35.979 4.670   1.000 17.383 0 184 ALA B CB  1 ? 
ATOM   3011 N N   . VAL B 1 150 ? -8.876  -35.955 6.409   1.000 18.733 0 185 VAL B N   1 ? 
ATOM   3012 C CA  . VAL B 1 150 ? -10.245 -35.458 6.438   1.000 18.093 0 185 VAL B CA  1 ? 
ATOM   3013 C C   . VAL B 1 150 ? -10.258 -34.013 6.949   1.000 17.230 0 185 VAL B C   1 ? 
ATOM   3014 O O   . VAL B 1 150 ? -10.305 -33.769 8.160   1.000 17.128 0 185 VAL B O   1 ? 
ATOM   3015 C CB  . VAL B 1 150 ? -11.189 -36.346 7.267   1.000 17.454 0 185 VAL B CB  1 ? 
ATOM   3016 C CG1 . VAL B 1 150 ? -12.606 -35.775 7.258   1.000 17.955 0 185 VAL B CG1 1 ? 
ATOM   3017 C CG2 . VAL B 1 150 ? -11.202 -37.791 6.777   1.000 18.816 0 185 VAL B CG2 1 ? 
ATOM   3018 N N   . PRO B 1 151 ? -10.199 -33.015 6.038   1.000 16.249 0 186 PRO B N   1 ? 
ATOM   3019 C CA  . PRO B 1 151 ? -10.460 -31.619 6.386   1.000 16.777 0 186 PRO B CA  1 ? 
ATOM   3020 C C   . PRO B 1 151 ? -11.952 -31.332 6.528   1.000 16.534 0 186 PRO B C   1 ? 
ATOM   3021 O O   . PRO B 1 151 ? -12.710 -31.504 5.580   1.000 16.262 0 186 PRO B O   1 ? 
ATOM   3022 C CB  . PRO B 1 151 ? -9.885  -30.793 5.224   1.000 16.614 0 186 PRO B CB  1 ? 
ATOM   3023 C CG  . PRO B 1 151 ? -9.082  -31.804 4.423   1.000 16.612 0 186 PRO B CG  1 ? 
ATOM   3024 C CD  . PRO B 1 151 ? -9.747  -33.145 4.650   1.000 17.091 0 186 PRO B CD  1 ? 
ATOM   3025 N N   . LEU B 1 152 ? -12.327 -30.873 7.728   1.000 17.115 0 187 LEU B N   1 ? 
ATOM   3026 C CA  . LEU B 1 152 ? -13.689 -30.485 8.058   1.000 17.503 0 187 LEU B CA  1 ? 
ATOM   3027 C C   . LEU B 1 152 ? -13.793 -28.961 8.022   1.000 17.358 0 187 LEU B C   1 ? 
ATOM   3028 O O   . LEU B 1 152 ? -13.030 -28.285 8.695   1.000 15.012 0 187 LEU B O   1 ? 
ATOM   3029 C CB  . LEU B 1 152 ? -14.030 -31.031 9.449   1.000 18.264 0 187 LEU B CB  1 ? 
ATOM   3030 C CG  . LEU B 1 152 ? -13.914 -32.547 9.660   1.000 19.154 0 187 LEU B CG  1 ? 
ATOM   3031 C CD1 . LEU B 1 152 ? -14.249 -32.908 11.114  1.000 19.269 0 187 LEU B CD1 1 ? 
ATOM   3032 C CD2 . LEU B 1 152 ? -14.800 -33.332 8.708   1.000 18.909 0 187 LEU B CD2 1 ? 
ATOM   3033 N N   . THR B 1 153 ? -14.767 -28.458 7.241   1.000 17.063 0 188 THR B N   1 ? 
ATOM   3034 C CA  . THR B 1 153 ? -14.992 -27.047 6.952   1.000 16.757 0 188 THR B CA  1 ? 
ATOM   3035 C C   . THR B 1 153 ? -13.659 -26.323 6.911   1.000 17.383 0 188 THR B C   1 ? 
ATOM   3036 O O   . THR B 1 153 ? -13.435 -25.369 7.661   1.000 17.592 0 188 THR B O   1 ? 
ATOM   3037 C CB  . THR B 1 153 ? -16.009 -26.410 7.913   1.000 17.409 0 188 THR B CB  1 ? 
ATOM   3038 O OG1 . THR B 1 153 ? -15.471 -26.382 9.235   1.000 17.961 0 188 THR B OG1 1 ? 
ATOM   3039 C CG2 . THR B 1 153 ? -17.324 -27.168 7.962   1.000 17.128 0 188 THR B CG2 1 ? 
ATOM   3040 N N   . PRO B 1 154 ? -12.738 -26.757 6.026   1.000 17.668 0 189 PRO B N   1 ? 
ATOM   3041 C CA  . PRO B 1 154 ? -11.379 -26.233 6.039   1.000 18.294 0 189 PRO B CA  1 ? 
ATOM   3042 C C   . PRO B 1 154 ? -11.331 -24.762 5.622   1.000 19.531 0 189 PRO B C   1 ? 
ATOM   3043 O O   . PRO B 1 154 ? -12.115 -24.315 4.773   1.000 18.314 0 189 PRO B O   1 ? 
ATOM   3044 C CB  . PRO B 1 154 ? -10.644 -27.116 5.021   1.000 18.343 0 189 PRO B CB  1 ? 
ATOM   3045 C CG  . PRO B 1 154 ? -11.746 -27.527 4.048   1.000 18.782 0 189 PRO B CG  1 ? 
ATOM   3046 C CD  . PRO B 1 154 ? -12.953 -27.736 4.946   1.000 17.895 0 189 PRO B CD  1 ? 
ATOM   3047 N N   . TRP B 1 155 ? -10.357 -24.068 6.220   1.000 19.994 0 190 TRP B N   1 ? 
ATOM   3048 C CA  . TRP B 1 155 ? -10.028 -22.684 5.946   1.000 21.202 0 190 TRP B CA  1 ? 
ATOM   3049 C C   . TRP B 1 155 ? -8.522  -22.560 5.682   1.000 20.533 0 190 TRP B C   1 ? 
ATOM   3050 O O   . TRP B 1 155 ? -7.728  -23.050 6.469   1.000 20.406 0 190 TRP B O   1 ? 
ATOM   3051 C CB  . TRP B 1 155 ? -10.463 -21.830 7.138   1.000 22.982 0 190 TRP B CB  1 ? 
ATOM   3052 C CG  . TRP B 1 155 ? -10.191 -20.378 6.897   1.000 25.067 0 190 TRP B CG  1 ? 
ATOM   3053 C CD1 . TRP B 1 155 ? -11.075 -19.480 6.381   1.000 25.772 0 190 TRP B CD1 1 ? 
ATOM   3054 C CD2 . TRP B 1 155 ? -8.928  -19.683 7.030   1.000 27.320 0 190 TRP B CD2 1 ? 
ATOM   3055 N NE1 . TRP B 1 155 ? -10.477 -18.263 6.236   1.000 27.383 0 190 TRP B NE1 1 ? 
ATOM   3056 C CE2 . TRP B 1 155 ? -9.163  -18.347 6.628   1.000 28.334 0 190 TRP B CE2 1 ? 
ATOM   3057 C CE3 . TRP B 1 155 ? -7.651  -20.032 7.515   1.000 27.127 0 190 TRP B CE3 1 ? 
ATOM   3058 C CZ2 . TRP B 1 155 ? -8.159  -17.373 6.666   1.000 29.710 0 190 TRP B CZ2 1 ? 
ATOM   3059 C CZ3 . TRP B 1 155 ? -6.666  -19.068 7.566   1.000 27.952 0 190 TRP B CZ3 1 ? 
ATOM   3060 C CH2 . TRP B 1 155 ? -6.918  -17.754 7.141   1.000 29.011 0 190 TRP B CH2 1 ? 
ATOM   3061 N N   . HIS B 1 156 ? -8.122  -21.893 4.594   1.000 20.165 0 191 HIS B N   1 ? 
ATOM   3062 C CA  . HIS B 1 156 ? -6.722  -21.509 4.389   1.000 21.372 0 191 HIS B CA  1 ? 
ATOM   3063 C C   . HIS B 1 156 ? -6.629  -20.463 3.271   1.000 22.610 0 191 HIS B C   1 ? 
ATOM   3064 O O   . HIS B 1 156 ? -7.524  -20.346 2.443   1.000 21.970 0 191 HIS B O   1 ? 
ATOM   3065 C CB  . HIS B 1 156 ? -5.851  -22.739 4.096   1.000 21.726 0 191 HIS B CB  1 ? 
ATOM   3066 C CG  . HIS B 1 156 ? -4.369  -22.492 4.010   1.000 21.313 0 191 HIS B CG  1 ? 
ATOM   3067 N ND1 . HIS B 1 156 ? -3.665  -21.692 4.890   1.000 21.344 0 191 HIS B ND1 1 ? 
ATOM   3068 C CD2 . HIS B 1 156 ? -3.461  -22.948 3.124   1.000 21.482 0 191 HIS B CD2 1 ? 
ATOM   3069 C CE1 . HIS B 1 156 ? -2.381  -21.679 4.534   1.000 21.733 0 191 HIS B CE1 1 ? 
ATOM   3070 N NE2 . HIS B 1 156 ? -2.231  -22.421 3.452   1.000 20.452 0 191 HIS B NE2 1 ? 
ATOM   3071 N N   . THR B 1 157 ? -5.523  -19.710 3.251   1.000 23.924 0 192 THR B N   1 ? 
ATOM   3072 C CA  . THR B 1 157 ? -5.320  -18.645 2.291   1.000 27.301 0 192 THR B CA  1 ? 
ATOM   3073 C C   . THR B 1 157 ? -4.752  -19.143 0.955   1.000 31.342 0 192 THR B C   1 ? 
ATOM   3074 O O   . THR B 1 157 ? -4.828  -18.412 -0.031  1.000 43.230 0 192 THR B O   1 ? 
ATOM   3075 C CB  . THR B 1 157 ? -4.449  -17.552 2.919   1.000 26.570 0 192 THR B CB  1 ? 
ATOM   3076 O OG1 . THR B 1 157 ? -3.257  -18.144 3.421   1.000 25.964 0 192 THR B OG1 1 ? 
ATOM   3077 C CG2 . THR B 1 157 ? -5.151  -16.828 4.046   1.000 28.277 0 192 THR B CG2 1 ? 
ATOM   3078 N N   . ASP B 1 158 ? -4.214  -20.367 0.880   1.000 29.537 0 193 ASP B N   1 ? 
ATOM   3079 C CA  . ASP B 1 158 ? -3.719  -20.944 -0.367  1.000 27.874 0 193 ASP B CA  1 ? 
ATOM   3080 C C   . ASP B 1 158 ? -4.546  -22.194 -0.690  1.000 26.928 0 193 ASP B C   1 ? 
ATOM   3081 O O   . ASP B 1 158 ? -5.052  -22.857 0.220   1.000 25.487 0 193 ASP B O   1 ? 
ATOM   3082 C CB  . ASP B 1 158 ? -2.217  -21.249 -0.268  1.000 32.335 0 193 ASP B CB  1 ? 
ATOM   3083 C CG  . ASP B 1 158 ? -1.350  -19.992 -0.178  1.000 39.113 0 193 ASP B CG  1 ? 
ATOM   3084 O OD1 . ASP B 1 158 ? -1.329  -19.232 -1.178  1.000 47.148 0 193 ASP B OD1 1 ? 
ATOM   3085 O OD2 . ASP B 1 158 ? -0.731  -19.741 0.904   1.000 49.361 0 193 ASP B OD2 1 ? 
ATOM   3086 N N   . LYS B 1 159 ? -4.716  -22.503 -1.986  1.000 23.351 0 194 LYS B N   1 ? 
ATOM   3087 C CA  . LYS B 1 159 ? -5.768  -23.407 -2.434  1.000 25.662 0 194 LYS B CA  1 ? 
ATOM   3088 C C   . LYS B 1 159 ? -5.222  -24.742 -2.963  1.000 23.290 0 194 LYS B C   1 ? 
ATOM   3089 O O   . LYS B 1 159 ? -5.993  -25.693 -3.098  1.000 21.329 0 194 LYS B O   1 ? 
ATOM   3090 C CB  . LYS B 1 159 ? -6.630  -22.717 -3.505  1.000 30.166 0 194 LYS B CB  1 ? 
ATOM   3091 C CG  . LYS B 1 159 ? -7.107  -21.303 -3.161  1.000 34.742 0 194 LYS B CG  1 ? 
ATOM   3092 C CD  . LYS B 1 159 ? -7.960  -21.212 -1.891  1.000 37.047 0 194 LYS B CD  1 ? 
ATOM   3093 C CE  . LYS B 1 159 ? -8.061  -19.841 -1.239  1.000 36.152 0 194 LYS B CE  1 ? 
ATOM   3094 N NZ  . LYS B 1 159 ? -8.814  -19.930 0.046   1.000 30.690 0 194 LYS B NZ  1 ? 
ATOM   3095 N N   . LYS B 1 160 ? -3.911  -24.828 -3.253  1.000 22.681 0 195 LYS B N   1 ? 
ATOM   3096 C CA  . LYS B 1 160 ? -3.358  -25.956 -3.988  1.000 23.997 0 195 LYS B CA  1 ? 
ATOM   3097 C C   . LYS B 1 160 ? -2.592  -26.893 -3.055  1.000 23.336 0 195 LYS B C   1 ? 
ATOM   3098 O O   . LYS B 1 160 ? -1.622  -26.489 -2.421  1.000 22.219 0 195 LYS B O   1 ? 
ATOM   3099 C CB  . LYS B 1 160 ? -2.435  -25.446 -5.093  1.000 26.112 0 195 LYS B CB  1 ? 
ATOM   3100 C CG  . LYS B 1 160 ? -3.109  -24.622 -6.183  1.000 29.239 0 195 LYS B CG  1 ? 
ATOM   3101 C CD  . LYS B 1 160 ? -2.109  -24.153 -7.242  1.000 31.596 0 195 LYS B CD  1 ? 
ATOM   3102 C CE  . LYS B 1 160 ? -2.715  -23.823 -8.593  1.000 30.717 0 195 LYS B CE  1 ? 
ATOM   3103 N NZ  . LYS B 1 160 ? -3.523  -24.945 -9.132  1.000 32.260 0 195 LYS B NZ  1 ? 
ATOM   3104 N N   . PHE B 1 161 ? -3.000  -28.168 -2.991  1.000 22.593 0 196 PHE B N   1 ? 
ATOM   3105 C CA  . PHE B 1 161 ? -2.272  -29.124 -2.170  1.000 22.331 0 196 PHE B CA  1 ? 
ATOM   3106 C C   . PHE B 1 161 ? -1.890  -30.321 -3.028  1.000 21.748 0 196 PHE B C   1 ? 
ATOM   3107 O O   . PHE B 1 161 ? -2.751  -31.077 -3.483  1.000 22.873 0 196 PHE B O   1 ? 
ATOM   3108 C CB  . PHE B 1 161 ? -3.097  -29.526 -0.942  1.000 22.878 0 196 PHE B CB  1 ? 
ATOM   3109 C CG  . PHE B 1 161 ? -3.541  -28.337 -0.131  1.000 20.499 0 196 PHE B CG  1 ? 
ATOM   3110 C CD1 . PHE B 1 161 ? -2.669  -27.712 0.744   1.000 19.905 0 196 PHE B CD1 1 ? 
ATOM   3111 C CD2 . PHE B 1 161 ? -4.784  -27.780 -0.345  1.000 20.530 0 196 PHE B CD2 1 ? 
ATOM   3112 C CE1 . PHE B 1 161 ? -3.054  -26.587 1.439   1.000 20.671 0 196 PHE B CE1 1 ? 
ATOM   3113 C CE2 . PHE B 1 161 ? -5.175  -26.658 0.365   1.000 22.140 0 196 PHE B CE2 1 ? 
ATOM   3114 C CZ  . PHE B 1 161 ? -4.314  -26.066 1.259   1.000 21.815 0 196 PHE B CZ  1 ? 
ATOM   3115 N N   . ASN B 1 162 ? -0.583  -30.475 -3.224  1.000 21.777 0 197 ASN B N   1 ? 
ATOM   3116 C CA  . ASN B 1 162 ? -0.038  -31.498 -4.084  1.000 21.986 0 197 ASN B CA  1 ? 
ATOM   3117 C C   . ASN B 1 162 ? 0.213   -32.734 -3.228  1.000 22.588 0 197 ASN B C   1 ? 
ATOM   3118 O O   . ASN B 1 162 ? 1.315   -32.913 -2.698  1.000 22.093 0 197 ASN B O   1 ? 
ATOM   3119 C CB  . ASN B 1 162 ? 1.230   -31.000 -4.773  1.000 22.979 0 197 ASN B CB  1 ? 
ATOM   3120 C CG  . ASN B 1 162 ? 1.774   -32.007 -5.759  1.000 25.309 0 197 ASN B CG  1 ? 
ATOM   3121 O OD1 . ASN B 1 162 ? 1.078   -32.949 -6.153  1.000 24.213 0 197 ASN B OD1 1 ? 
ATOM   3122 N ND2 . ASN B 1 162 ? 2.996   -31.775 -6.200  1.000 22.045 0 197 ASN B ND2 1 ? 
ATOM   3123 N N   . THR B 1 163 ? -0.848  -33.532 -3.050  1.000 22.349 0 198 THR B N   1 ? 
ATOM   3124 C CA  . THR B 1 163 ? -0.819  -34.686 -2.172  1.000 25.138 0 198 THR B CA  1 ? 
ATOM   3125 C C   . THR B 1 163 ? -1.435  -35.899 -2.858  1.000 24.794 0 198 THR B C   1 ? 
ATOM   3126 O O   . THR B 1 163 ? -2.439  -35.789 -3.563  1.000 23.882 0 198 THR B O   1 ? 
ATOM   3127 C CB  . THR B 1 163 ? -1.514  -34.423 -0.825  1.000 26.032 0 198 THR B CB  1 ? 
ATOM   3128 O OG1 . THR B 1 163 ? -1.272  -35.571 -0.008  1.000 24.837 0 198 THR B OG1 1 ? 
ATOM   3129 C CG2 . THR B 1 163 ? -2.999  -34.185 -0.923  1.000 25.018 0 198 THR B CG2 1 ? 
ATOM   3130 N N   . LYS B 1 164 ? -0.803  -37.046 -2.580  1.000 26.331 0 199 LYS B N   1 ? 
ATOM   3131 C CA  . LYS B 1 164 ? -1.266  -38.368 -2.965  1.000 29.594 0 199 LYS B CA  1 ? 
ATOM   3132 C C   . LYS B 1 164 ? -2.188  -38.966 -1.909  1.000 22.898 0 199 LYS B C   1 ? 
ATOM   3133 O O   . LYS B 1 164 ? -2.785  -40.007 -2.163  1.000 21.264 0 199 LYS B O   1 ? 
ATOM   3134 C CB  . LYS B 1 164 ? -0.096  -39.366 -3.056  1.000 37.445 0 199 LYS B CB  1 ? 
ATOM   3135 C CG  . LYS B 1 164 ? 1.112   -38.951 -3.892  1.000 48.222 0 199 LYS B CG  1 ? 
ATOM   3136 C CD  . LYS B 1 164 ? 0.817   -38.617 -5.350  1.000 56.473 0 199 LYS B CD  1 ? 
ATOM   3137 C CE  . LYS B 1 164 ? 0.608   -39.841 -6.217  1.000 64.241 0 199 LYS B CE  1 ? 
ATOM   3138 N NZ  . LYS B 1 164 ? 1.822   -40.686 -6.277  1.000 66.066 0 199 LYS B NZ  1 ? 
ATOM   3139 N N   . VAL B 1 165 ? -2.231  -38.359 -0.708  1.000 19.700 0 200 VAL B N   1 ? 
ATOM   3140 C CA  . VAL B 1 165 ? -3.000  -38.888 0.411   1.000 18.367 0 200 VAL B CA  1 ? 
ATOM   3141 C C   . VAL B 1 165 ? -4.487  -38.767 0.082   1.000 16.413 0 200 VAL B C   1 ? 
ATOM   3142 O O   . VAL B 1 165 ? -4.934  -37.727 -0.392  1.000 16.107 0 200 VAL B O   1 ? 
ATOM   3143 C CB  . VAL B 1 165 ? -2.662  -38.135 1.711   1.000 18.803 0 200 VAL B CB  1 ? 
ATOM   3144 C CG1 . VAL B 1 165 ? -3.458  -38.659 2.888   1.000 18.005 0 200 VAL B CG1 1 ? 
ATOM   3145 C CG2 . VAL B 1 165 ? -1.168  -38.168 2.007   1.000 18.833 0 200 VAL B CG2 1 ? 
ATOM   3146 N N   . PRO B 1 166 ? -5.299  -39.833 0.209   1.000 16.280 0 201 PRO B N   1 ? 
ATOM   3147 C CA  . PRO B 1 166 ? -6.735  -39.694 -0.019  1.000 16.722 0 201 PRO B CA  1 ? 
ATOM   3148 C C   . PRO B 1 166 ? -7.381  -38.619 0.857   1.000 16.134 0 201 PRO B C   1 ? 
ATOM   3149 O O   . PRO B 1 166 ? -7.257  -38.653 2.082   1.000 17.267 0 201 PRO B O   1 ? 
ATOM   3150 C CB  . PRO B 1 166 ? -7.264  -41.097 0.301   1.000 16.544 0 201 PRO B CB  1 ? 
ATOM   3151 C CG  . PRO B 1 166 ? -6.111  -42.006 -0.035  1.000 17.364 0 201 PRO B CG  1 ? 
ATOM   3152 C CD  . PRO B 1 166 ? -4.897  -41.232 0.426   1.000 16.955 0 201 PRO B CD  1 ? 
ATOM   3153 N N   . VAL B 1 167 ? -8.082  -37.676 0.222   1.000 16.110 0 202 VAL B N   1 ? 
ATOM   3154 C CA  . VAL B 1 167 ? -8.668  -36.535 0.917   1.000 16.273 0 202 VAL B CA  1 ? 
ATOM   3155 C C   . VAL B 1 167 ? -10.190 -36.588 0.838   1.000 16.758 0 202 VAL B C   1 ? 
ATOM   3156 O O   . VAL B 1 167 ? -10.735 -36.577 -0.259  1.000 16.355 0 202 VAL B O   1 ? 
ATOM   3157 C CB  . VAL B 1 167 ? -8.177  -35.211 0.294   1.000 17.214 0 202 VAL B CB  1 ? 
ATOM   3158 C CG1 . VAL B 1 167 ? -8.938  -34.002 0.837   1.000 18.162 0 202 VAL B CG1 1 ? 
ATOM   3159 C CG2 . VAL B 1 167 ? -6.672  -35.040 0.462   1.000 17.525 0 202 VAL B CG2 1 ? 
ATOM   3160 N N   . LEU B 1 168 ? -10.838 -36.553 2.005   1.000 17.427 0 203 LEU B N   1 ? 
ATOM   3161 C CA  . LEU B 1 168 ? -12.270 -36.322 2.132   1.000 17.195 0 203 LEU B CA  1 ? 
ATOM   3162 C C   . LEU B 1 168 ? -12.519 -34.946 2.756   1.000 17.087 0 203 LEU B C   1 ? 
ATOM   3163 O O   . LEU B 1 168 ? -12.305 -34.744 3.952   1.000 14.776 0 203 LEU B O   1 ? 
ATOM   3164 C CB  . LEU B 1 168 ? -12.893 -37.438 2.972   1.000 18.928 0 203 LEU B CB  1 ? 
ATOM   3165 C CG  . LEU B 1 168 ? -14.263 -37.137 3.586   1.000 19.467 0 203 LEU B CG  1 ? 
ATOM   3166 C CD1 . LEU B 1 168 ? -15.316 -36.898 2.534   1.000 19.613 0 203 LEU B CD1 1 ? 
ATOM   3167 C CD2 . LEU B 1 168 ? -14.681 -38.273 4.498   1.000 20.729 0 203 LEU B CD2 1 ? 
ATOM   3168 N N   . ILE B 1 169 ? -12.986 -34.008 1.921   1.000 16.108 0 204 ILE B N   1 ? 
ATOM   3169 C CA  . ILE B 1 169 ? -13.297 -32.656 2.355   1.000 17.524 0 204 ILE B CA  1 ? 
ATOM   3170 C C   . ILE B 1 169 ? -14.789 -32.583 2.650   1.000 17.714 0 204 ILE B C   1 ? 
ATOM   3171 O O   . ILE B 1 169 ? -15.593 -32.932 1.796   1.000 17.554 0 204 ILE B O   1 ? 
ATOM   3172 C CB  . ILE B 1 169 ? -12.900 -31.632 1.276   1.000 18.185 0 204 ILE B CB  1 ? 
ATOM   3173 C CG1 . ILE B 1 169 ? -11.381 -31.487 1.187   1.000 19.112 0 204 ILE B CG1 1 ? 
ATOM   3174 C CG2 . ILE B 1 169 ? -13.567 -30.287 1.538   1.000 20.090 0 204 ILE B CG2 1 ? 
ATOM   3175 C CD1 . ILE B 1 169 ? -10.886 -30.851 -0.064  1.000 18.807 0 204 ILE B CD1 1 ? 
ATOM   3176 N N   . ILE B 1 170 ? -15.134 -32.159 3.869   1.000 17.535 0 205 ILE B N   1 ? 
ATOM   3177 C CA  . ILE B 1 170 ? -16.516 -31.941 4.245   1.000 18.299 0 205 ILE B CA  1 ? 
ATOM   3178 C C   . ILE B 1 170 ? -16.719 -30.447 4.495   1.000 18.998 0 205 ILE B C   1 ? 
ATOM   3179 O O   . ILE B 1 170 ? -16.141 -29.872 5.423   1.000 17.258 0 205 ILE B O   1 ? 
ATOM   3180 C CB  . ILE B 1 170 ? -16.942 -32.799 5.448   1.000 18.707 0 205 ILE B CB  1 ? 
ATOM   3181 C CG1 . ILE B 1 170 ? -16.735 -34.289 5.163   1.000 18.451 0 205 ILE B CG1 1 ? 
ATOM   3182 C CG2 . ILE B 1 170 ? -18.379 -32.492 5.800   1.000 19.852 0 205 ILE B CG2 1 ? 
ATOM   3183 C CD1 . ILE B 1 170 ? -17.163 -35.224 6.273   1.000 19.144 0 205 ILE B CD1 1 ? 
ATOM   3184 N N   . GLY B 1 171 ? -17.534 -29.833 3.625   1.000 17.986 0 206 GLY B N   1 ? 
ATOM   3185 C CA  . GLY B 1 171 ? -17.883 -28.429 3.754   1.000 18.560 0 206 GLY B CA  1 ? 
ATOM   3186 C C   . GLY B 1 171 ? -19.294 -28.243 4.304   1.000 18.614 0 206 GLY B C   1 ? 
ATOM   3187 O O   . GLY B 1 171 ? -20.042 -29.211 4.456   1.000 17.675 0 206 GLY B O   1 ? 
ATOM   3188 N N   . ALA B 1 172 ? -19.629 -26.978 4.590   1.000 19.904 0 207 ALA B N   1 ? 
ATOM   3189 C CA  . ALA B 1 172 ? -20.922 -26.583 5.137   1.000 18.211 0 207 ALA B CA  1 ? 
ATOM   3190 C C   . ALA B 1 172 ? -21.560 -25.596 4.170   1.000 17.814 0 207 ALA B C   1 ? 
ATOM   3191 O O   . ALA B 1 172 ? -20.925 -24.630 3.774   1.000 15.568 0 207 ALA B O   1 ? 
ATOM   3192 C CB  . ALA B 1 172 ? -20.778 -25.959 6.508   1.000 18.745 0 207 ALA B CB  1 ? 
ATOM   3193 N N   . GLU B 1 173 ? -22.819 -25.848 3.804   1.000 17.989 0 208 GLU B N   1 ? 
ATOM   3194 C CA  . GLU B 1 173 ? -23.477 -25.061 2.783   1.000 20.049 0 208 GLU B CA  1 ? 
ATOM   3195 C C   . GLU B 1 173 ? -23.597 -23.591 3.201   1.000 20.172 0 208 GLU B C   1 ? 
ATOM   3196 O O   . GLU B 1 173 ? -23.479 -22.704 2.362   1.000 19.684 0 208 GLU B O   1 ? 
ATOM   3197 C CB  . GLU B 1 173 ? -24.862 -25.641 2.525   1.000 22.926 0 208 GLU B CB  1 ? 
ATOM   3198 C CG  . GLU B 1 173 ? -25.541 -25.013 1.337   1.000 25.702 0 208 GLU B CG  1 ? 
ATOM   3199 C CD  . GLU B 1 173 ? -26.947 -25.507 1.113   1.000 28.630 0 208 GLU B CD  1 ? 
ATOM   3200 O OE1 . GLU B 1 173 ? -27.584 -26.003 2.084   1.000 30.627 0 208 GLU B OE1 1 ? 
ATOM   3201 O OE2 . GLU B 1 173 ? -27.384 -25.400 -0.041  1.000 34.787 0 208 GLU B OE2 1 ? 
ATOM   3202 N N   . ALA B 1 174 ? -23.853 -23.321 4.488   1.000 21.517 0 209 ALA B N   1 ? 
ATOM   3203 C CA  . ALA B 1 174 ? -24.090 -21.952 4.952   1.000 21.993 0 209 ALA B CA  1 ? 
ATOM   3204 C C   . ALA B 1 174 ? -22.887 -21.385 5.714   1.000 21.523 0 209 ALA B C   1 ? 
ATOM   3205 O O   . ALA B 1 174 ? -23.055 -20.528 6.567   1.000 21.346 0 209 ALA B O   1 ? 
ATOM   3206 C CB  . ALA B 1 174 ? -25.354 -21.902 5.797   1.000 22.485 0 209 ALA B CB  1 ? 
ATOM   3207 N N   . ASP B 1 175 ? -21.673 -21.793 5.345   1.000 21.068 0 210 ASP B N   1 ? 
ATOM   3208 C CA  . ASP B 1 175 ? -20.473 -21.419 6.072   1.000 20.118 0 210 ASP B CA  1 ? 
ATOM   3209 C C   . ASP B 1 175 ? -20.177 -19.926 5.871   1.000 19.406 0 210 ASP B C   1 ? 
ATOM   3210 O O   . ASP B 1 175 ? -19.858 -19.499 4.767   1.000 20.789 0 210 ASP B O   1 ? 
ATOM   3211 C CB  . ASP B 1 175 ? -19.299 -22.295 5.610   1.000 17.948 0 210 ASP B CB  1 ? 
ATOM   3212 C CG  . ASP B 1 175 ? -18.119 -22.285 6.561   1.000 17.347 0 210 ASP B CG  1 ? 
ATOM   3213 O OD1 . ASP B 1 175 ? -17.873 -21.206 7.162   1.000 17.867 0 210 ASP B OD1 1 ? 
ATOM   3214 O OD2 . ASP B 1 175 ? -17.436 -23.334 6.676   1.000 15.417 0 210 ASP B OD2 1 ? 
ATOM   3215 N N   . THR B 1 176 ? -20.218 -19.143 6.956   1.000 18.838 0 211 THR B N   1 ? 
ATOM   3216 C CA  . THR B 1 176 ? -19.943 -17.709 6.891   1.000 19.081 0 211 THR B CA  1 ? 
ATOM   3217 C C   . THR B 1 176 ? -18.448 -17.378 7.011   1.000 20.721 0 211 THR B C   1 ? 
ATOM   3218 O O   . THR B 1 176 ? -18.064 -16.215 6.854   1.000 22.341 0 211 THR B O   1 ? 
ATOM   3219 C CB  . THR B 1 176 ? -20.694 -16.961 8.004   1.000 19.333 0 211 THR B CB  1 ? 
ATOM   3220 O OG1 . THR B 1 176 ? -20.299 -17.451 9.295   1.000 18.904 0 211 THR B OG1 1 ? 
ATOM   3221 C CG2 . THR B 1 176 ? -22.190 -17.096 7.847   1.000 20.602 0 211 THR B CG2 1 ? 
ATOM   3222 N N   . VAL B 1 177 ? -17.613 -18.356 7.384   1.000 19.828 0 212 VAL B N   1 ? 
ATOM   3223 C CA  . VAL B 1 177 ? -16.214 -18.103 7.703   1.000 20.628 0 212 VAL B CA  1 ? 
ATOM   3224 C C   . VAL B 1 177 ? -15.328 -18.666 6.582   1.000 19.890 0 212 VAL B C   1 ? 
ATOM   3225 O O   . VAL B 1 177 ? -14.325 -18.069 6.229   1.000 19.370 0 212 VAL B O   1 ? 
ATOM   3226 C CB  . VAL B 1 177 ? -15.855 -18.695 9.086   1.000 22.207 0 212 VAL B CB  1 ? 
ATOM   3227 C CG1 . VAL B 1 177 ? -14.346 -18.830 9.295   1.000 24.581 0 212 VAL B CG1 1 ? 
ATOM   3228 C CG2 . VAL B 1 177 ? -16.467 -17.854 10.196  1.000 23.718 0 212 VAL B CG2 1 ? 
ATOM   3229 N N   . ALA B 1 178 ? -15.646 -19.861 6.092   1.000 18.494 0 213 ALA B N   1 ? 
ATOM   3230 C CA  . ALA B 1 178 ? -14.856 -20.496 5.044   1.000 20.286 0 213 ALA B CA  1 ? 
ATOM   3231 C C   . ALA B 1 178 ? -15.828 -20.970 3.969   1.000 19.593 0 213 ALA B C   1 ? 
ATOM   3232 O O   . ALA B 1 178 ? -16.058 -22.166 3.808   1.000 20.948 0 213 ALA B O   1 ? 
ATOM   3233 C CB  . ALA B 1 178 ? -14.040 -21.648 5.602   1.000 20.389 0 213 ALA B CB  1 ? 
ATOM   3234 N N   . PRO B 1 179 ? -16.480 -20.041 3.236   1.000 20.465 0 214 PRO B N   1 ? 
ATOM   3235 C CA  . PRO B 1 179 ? -17.464 -20.435 2.230   1.000 20.840 0 214 PRO B CA  1 ? 
ATOM   3236 C C   . PRO B 1 179 ? -16.812 -21.444 1.280   1.000 19.996 0 214 PRO B C   1 ? 
ATOM   3237 O O   . PRO B 1 179 ? -15.642 -21.304 0.904   1.000 21.511 0 214 PRO B O   1 ? 
ATOM   3238 C CB  . PRO B 1 179 ? -17.877 -19.102 1.584   1.000 21.198 0 214 PRO B CB  1 ? 
ATOM   3239 C CG  . PRO B 1 179 ? -16.799 -18.123 1.989   1.000 21.946 0 214 PRO B CG  1 ? 
ATOM   3240 C CD  . PRO B 1 179 ? -16.303 -18.585 3.335   1.000 20.851 0 214 PRO B CD  1 ? 
ATOM   3241 N N   . VAL B 1 180 ? -17.566 -22.479 0.924   1.000 19.876 0 215 VAL B N   1 ? 
ATOM   3242 C CA  . VAL B 1 180 ? -17.001 -23.588 0.159   1.000 19.856 0 215 VAL B CA  1 ? 
ATOM   3243 C C   . VAL B 1 180 ? -16.529 -23.101 -1.211  1.000 20.688 0 215 VAL B C   1 ? 
ATOM   3244 O O   . VAL B 1 180 ? -15.576 -23.648 -1.776  1.000 18.454 0 215 VAL B O   1 ? 
ATOM   3245 C CB  . VAL B 1 180 ? -17.971 -24.776 0.039   1.000 18.689 0 215 VAL B CB  1 ? 
ATOM   3246 C CG1 . VAL B 1 180 ? -18.309 -25.335 1.405   1.000 18.297 0 215 VAL B CG1 1 ? 
ATOM   3247 C CG2 . VAL B 1 180 ? -19.241 -24.437 -0.732  1.000 19.454 0 215 VAL B CG2 1 ? 
ATOM   3248 N N   . SER B 1 181 ? -17.164 -22.054 -1.744  1.000 22.048 0 216 SER B N   1 ? 
ATOM   3249 C CA  . SER B 1 181 ? -16.776 -21.535 -3.043  1.000 22.616 0 216 SER B CA  1 ? 
ATOM   3250 C C   . SER B 1 181 ? -15.367 -20.960 -2.994  1.000 24.355 0 216 SER B C   1 ? 
ATOM   3251 O O   . SER B 1 181 ? -14.718 -20.894 -4.027  1.000 25.702 0 216 SER B O   1 ? 
ATOM   3252 C CB  . SER B 1 181 ? -17.746 -20.498 -3.526  1.000 25.831 0 216 SER B CB  1 ? 
ATOM   3253 O OG  . SER B 1 181 ? -17.573 -19.293 -2.792  1.000 26.257 0 216 SER B OG  1 ? 
ATOM   3254 N N   . GLN B 1 182 ? -14.864 -20.566 -1.815  1.000 24.533 0 217 GLN B N   1 ? 
ATOM   3255 C CA  . GLN B 1 182 ? -13.524 -19.996 -1.742  1.000 25.664 0 217 GLN B CA  1 ? 
ATOM   3256 C C   . GLN B 1 182 ? -12.527 -20.893 -1.006  1.000 23.139 0 217 GLN B C   1 ? 
ATOM   3257 O O   . GLN B 1 182 ? -11.312 -20.634 -1.057  1.000 22.709 0 217 GLN B O   1 ? 
ATOM   3258 C CB  . GLN B 1 182 ? -13.586 -18.652 -1.035  1.000 30.166 0 217 GLN B CB  1 ? 
ATOM   3259 C CG  . GLN B 1 182 ? -14.418 -17.614 -1.765  1.000 35.112 0 217 GLN B CG  1 ? 
ATOM   3260 C CD  . GLN B 1 182 ? -14.606 -16.428 -0.848  1.000 41.461 0 217 GLN B CD  1 ? 
ATOM   3261 O OE1 . GLN B 1 182 ? -13.654 -15.736 -0.495  1.000 47.934 0 217 GLN B OE1 1 ? 
ATOM   3262 N NE2 . GLN B 1 182 ? -15.832 -16.216 -0.398  1.000 45.614 0 217 GLN B NE2 1 ? 
ATOM   3263 N N   . HIS B 1 183 ? -13.026 -21.924 -0.305  1.000 20.091 0 218 HIS B N   1 ? 
ATOM   3264 C CA  . HIS B 1 183 ? -12.161 -22.787 0.494   1.000 20.212 0 218 HIS B CA  1 ? 
ATOM   3265 C C   . HIS B 1 183 ? -12.313 -24.233 0.029   1.000 20.262 0 218 HIS B C   1 ? 
ATOM   3266 O O   . HIS B 1 183 ? -11.639 -24.654 -0.903  1.000 21.836 0 218 HIS B O   1 ? 
ATOM   3267 C CB  . HIS B 1 183 ? -12.382 -22.518 1.992   1.000 19.540 0 218 HIS B CB  1 ? 
ATOM   3268 C CG  . HIS B 1 183 ? -11.982 -21.136 2.400   1.000 17.578 0 218 HIS B CG  1 ? 
ATOM   3269 N ND1 . HIS B 1 183 ? -10.700 -20.818 2.787   1.000 19.340 0 218 HIS B ND1 1 ? 
ATOM   3270 C CD2 . HIS B 1 183 ? -12.652 -19.989 2.377   1.000 18.590 0 218 HIS B CD2 1 ? 
ATOM   3271 C CE1 . HIS B 1 183 ? -10.616 -19.527 3.047   1.000 18.282 0 218 HIS B CE1 1 ? 
ATOM   3272 N NE2 . HIS B 1 183 ? -11.803 -19.004 2.818   1.000 17.600 0 218 HIS B NE2 1 ? 
ATOM   3273 N N   . ALA B 1 184 ? -13.247 -24.964 0.640   1.000 19.127 0 219 ALA B N   1 ? 
ATOM   3274 C CA  . ALA B 1 184 ? -13.397 -26.397 0.410   1.000 18.630 0 219 ALA B CA  1 ? 
ATOM   3275 C C   . ALA B 1 184 ? -13.373 -26.767 -1.069  1.000 18.372 0 219 ALA B C   1 ? 
ATOM   3276 O O   . ALA B 1 184 ? -12.728 -27.740 -1.433  1.000 17.337 0 219 ALA B O   1 ? 
ATOM   3277 C CB  . ALA B 1 184 ? -14.673 -26.907 1.032   1.000 17.632 0 219 ALA B CB  1 ? 
ATOM   3278 N N   . LEU B 1 185 ? -14.135 -26.070 -1.921  1.000 20.563 0 220 LEU B N   1 ? 
ATOM   3279 C CA  . LEU B 1 185 ? -14.215 -26.513 -3.311  1.000 20.964 0 220 LEU B CA  1 ? 
ATOM   3280 C C   . LEU B 1 185 ? -12.894 -26.254 -4.052  1.000 19.338 0 220 LEU B C   1 ? 
ATOM   3281 O O   . LEU B 1 185 ? -12.390 -27.187 -4.682  1.000 18.169 0 220 LEU B O   1 ? 
ATOM   3282 C CB  . LEU B 1 185 ? -15.422 -25.901 -4.023  1.000 21.662 0 220 LEU B CB  1 ? 
ATOM   3283 C CG  . LEU B 1 185 ? -15.611 -26.340 -5.478  1.000 23.314 0 220 LEU B CG  1 ? 
ATOM   3284 C CD1 . LEU B 1 185 ? -15.609 -27.859 -5.606  1.000 24.005 0 220 LEU B CD1 1 ? 
ATOM   3285 C CD2 . LEU B 1 185 ? -16.911 -25.782 -6.062  1.000 22.542 0 220 LEU B CD2 1 ? 
ATOM   3286 N N   . PRO B 1 186 ? -12.291 -25.030 -4.064  1.000 18.581 0 221 PRO B N   1 ? 
ATOM   3287 C CA  . PRO B 1 186 ? -10.935 -24.865 -4.600  1.000 19.135 0 221 PRO B CA  1 ? 
ATOM   3288 C C   . PRO B 1 186 ? -9.938  -25.909 -4.086  1.000 19.367 0 221 PRO B C   1 ? 
ATOM   3289 O O   . PRO B 1 186 ? -9.146  -26.442 -4.861  1.000 19.872 0 221 PRO B O   1 ? 
ATOM   3290 C CB  . PRO B 1 186 ? -10.534 -23.443 -4.187  1.000 18.714 0 221 PRO B CB  1 ? 
ATOM   3291 C CG  . PRO B 1 186 ? -11.824 -22.696 -4.062  1.000 19.405 0 221 PRO B CG  1 ? 
ATOM   3292 C CD  . PRO B 1 186 ? -12.869 -23.732 -3.671  1.000 19.771 0 221 PRO B CD  1 ? 
ATOM   3293 N N   . PHE B 1 187 ? -9.998  -26.238 -2.785  1.000 20.247 0 222 PHE B N   1 ? 
ATOM   3294 C CA  . PHE B 1 187 ? -9.099  -27.236 -2.227  1.000 20.289 0 222 PHE B CA  1 ? 
ATOM   3295 C C   . PHE B 1 187 ? -9.299  -28.571 -2.945  1.000 19.178 0 222 PHE B C   1 ? 
ATOM   3296 O O   . PHE B 1 187 ? -8.339  -29.210 -3.345  1.000 19.238 0 222 PHE B O   1 ? 
ATOM   3297 C CB  . PHE B 1 187 ? -9.291  -27.410 -0.718  1.000 21.941 0 222 PHE B CB  1 ? 
ATOM   3298 C CG  . PHE B 1 187 ? -9.115  -26.173 0.134   1.000 22.220 0 222 PHE B CG  1 ? 
ATOM   3299 C CD1 . PHE B 1 187 ? -8.424  -25.065 -0.317  1.000 23.307 0 222 PHE B CD1 1 ? 
ATOM   3300 C CD2 . PHE B 1 187 ? -9.718  -26.099 1.379   1.000 22.529 0 222 PHE B CD2 1 ? 
ATOM   3301 C CE1 . PHE B 1 187 ? -8.297  -23.933 0.476   1.000 22.300 0 222 PHE B CE1 1 ? 
ATOM   3302 C CE2 . PHE B 1 187 ? -9.596  -24.967 2.172   1.000 22.053 0 222 PHE B CE2 1 ? 
ATOM   3303 C CZ  . PHE B 1 187 ? -8.869  -23.892 1.721   1.000 21.369 0 222 PHE B CZ  1 ? 
ATOM   3304 N N   . PHE B 1 188 ? -10.551 -28.993 -3.111  1.000 19.407 0 223 PHE B N   1 ? 
ATOM   3305 C CA  . PHE B 1 188 ? -10.859 -30.233 -3.809  1.000 18.567 0 223 PHE B CA  1 ? 
ATOM   3306 C C   . PHE B 1 188 ? -10.411 -30.168 -5.271  1.000 19.617 0 223 PHE B C   1 ? 
ATOM   3307 O O   . PHE B 1 188 ? -9.794  -31.096 -5.773  1.000 18.890 0 223 PHE B O   1 ? 
ATOM   3308 C CB  . PHE B 1 188 ? -12.361 -30.521 -3.739  1.000 19.644 0 223 PHE B CB  1 ? 
ATOM   3309 C CG  . PHE B 1 188 ? -12.799 -31.753 -4.494  1.000 19.464 0 223 PHE B CG  1 ? 
ATOM   3310 C CD1 . PHE B 1 188 ? -12.689 -33.028 -3.944  1.000 18.750 0 223 PHE B CD1 1 ? 
ATOM   3311 C CD2 . PHE B 1 188 ? -13.304 -31.638 -5.785  1.000 21.968 0 223 PHE B CD2 1 ? 
ATOM   3312 C CE1 . PHE B 1 188 ? -13.114 -34.144 -4.657  1.000 18.438 0 223 PHE B CE1 1 ? 
ATOM   3313 C CE2 . PHE B 1 188 ? -13.703 -32.756 -6.507  1.000 19.390 0 223 PHE B CE2 1 ? 
ATOM   3314 C CZ  . PHE B 1 188 ? -13.618 -34.009 -5.933  1.000 19.627 0 223 PHE B CZ  1 ? 
ATOM   3315 N N   . GLU B 1 189 ? -10.703 -29.054 -5.952  1.000 20.803 0 224 GLU B N   1 ? 
ATOM   3316 C CA  . GLU B 1 189 ? -10.470 -28.954 -7.381  1.000 21.302 0 224 GLU B CA  1 ? 
ATOM   3317 C C   . GLU B 1 189 ? -8.985  -28.925 -7.706  1.000 21.857 0 224 GLU B C   1 ? 
ATOM   3318 O O   . GLU B 1 189 ? -8.612  -29.326 -8.797  1.000 22.077 0 224 GLU B O   1 ? 
ATOM   3319 C CB  . GLU B 1 189 ? -11.169 -27.727 -7.950  1.000 23.842 0 224 GLU B CB  1 ? 
ATOM   3320 C CG  . GLU B 1 189 ? -12.669 -27.907 -8.042  1.000 28.232 0 224 GLU B CG  1 ? 
ATOM   3321 C CD  . GLU B 1 189 ? -13.435 -26.709 -8.583  1.000 35.195 0 224 GLU B CD  1 ? 
ATOM   3322 O OE1 . GLU B 1 189 ? -12.852 -25.586 -8.635  1.000 41.321 0 224 GLU B OE1 1 ? 
ATOM   3323 O OE2 . GLU B 1 189 ? -14.605 -26.903 -8.963  1.000 44.043 0 224 GLU B OE2 1 ? 
ATOM   3324 N N   . ASN B 1 190 ? -8.139  -28.503 -6.770  1.000 19.592 0 225 ASN B N   1 ? 
ATOM   3325 C CA  . ASN B 1 190 ? -6.723  -28.354 -7.060  1.000 20.343 0 225 ASN B CA  1 ? 
ATOM   3326 C C   . ASN B 1 190 ? -5.901  -29.558 -6.589  1.000 19.769 0 225 ASN B C   1 ? 
ATOM   3327 O O   . ASN B 1 190 ? -4.674  -29.526 -6.670  1.000 20.396 0 225 ASN B O   1 ? 
ATOM   3328 C CB  . ASN B 1 190 ? -6.214  -27.054 -6.450  1.000 21.986 0 225 ASN B CB  1 ? 
ATOM   3329 C CG  . ASN B 1 190 ? -6.704  -25.856 -7.234  1.000 23.265 0 225 ASN B CG  1 ? 
ATOM   3330 O OD1 . ASN B 1 190 ? -6.204  -25.608 -8.319  1.000 24.497 0 225 ASN B OD1 1 ? 
ATOM   3331 N ND2 . ASN B 1 190 ? -7.688  -25.136 -6.729  1.000 24.176 0 225 ASN B ND2 1 ? 
ATOM   3332 N N   . LEU B 1 191 ? -6.554  -30.610 -6.068  1.000 20.605 0 226 LEU B N   1 ? 
ATOM   3333 C CA  . LEU B 1 191 ? -5.842  -31.821 -5.676  1.000 21.053 0 226 LEU B CA  1 ? 
ATOM   3334 C C   . LEU B 1 191 ? -5.350  -32.488 -6.949  1.000 22.334 0 226 LEU B C   1 ? 
ATOM   3335 O O   . LEU B 1 191 ? -5.974  -32.330 -7.994  1.000 22.879 0 226 LEU B O   1 ? 
ATOM   3336 C CB  . LEU B 1 191 ? -6.759  -32.777 -4.911  1.000 20.622 0 226 LEU B CB  1 ? 
ATOM   3337 C CG  . LEU B 1 191 ? -7.136  -32.360 -3.494  1.000 21.697 0 226 LEU B CG  1 ? 
ATOM   3338 C CD1 . LEU B 1 191 ? -8.212  -33.283 -2.921  1.000 21.656 0 226 LEU B CD1 1 ? 
ATOM   3339 C CD2 . LEU B 1 191 ? -5.914  -32.317 -2.602  1.000 21.047 0 226 LEU B CD2 1 ? 
ATOM   3340 N N   . PRO B 1 192 ? -4.247  -33.269 -6.923  1.000 23.972 0 227 PRO B N   1 ? 
ATOM   3341 C CA  . PRO B 1 192 ? -3.791  -33.962 -8.132  1.000 23.859 0 227 PRO B CA  1 ? 
ATOM   3342 C C   . PRO B 1 192 ? -4.887  -34.875 -8.672  1.000 25.112 0 227 PRO B C   1 ? 
ATOM   3343 O O   . PRO B 1 192 ? -5.712  -35.384 -7.895  1.000 22.696 0 227 PRO B O   1 ? 
ATOM   3344 C CB  . PRO B 1 192 ? -2.562  -34.756 -7.660  1.000 24.706 0 227 PRO B CB  1 ? 
ATOM   3345 C CG  . PRO B 1 192 ? -2.096  -33.996 -6.415  1.000 24.389 0 227 PRO B CG  1 ? 
ATOM   3346 C CD  . PRO B 1 192 ? -3.375  -33.507 -5.763  1.000 23.747 0 227 PRO B CD  1 ? 
ATOM   3347 N N   . LYS B 1 193 ? -4.889  -35.064 -10.000 1.000 27.519 0 228 LYS B N   1 ? 
ATOM   3348 C CA  . LYS B 1 193 ? -6.033  -35.665 -10.664 1.000 27.913 0 228 LYS B CA  1 ? 
ATOM   3349 C C   . LYS B 1 193 ? -6.173  -37.141 -10.302 1.000 25.602 0 228 LYS B C   1 ? 
ATOM   3350 O O   . LYS B 1 193 ? -7.279  -37.646 -10.360 1.000 26.562 0 228 LYS B O   1 ? 
ATOM   3351 C CB  . LYS B 1 193 ? -5.945  -35.499 -12.176 1.000 31.861 0 228 LYS B CB  1 ? 
ATOM   3352 C CG  . LYS B 1 193 ? -4.820  -36.254 -12.856 1.000 35.373 0 228 LYS B CG  1 ? 
ATOM   3353 C CD  . LYS B 1 193 ? -4.579  -35.715 -14.255 1.000 40.519 0 228 LYS B CD  1 ? 
ATOM   3354 C CE  . LYS B 1 193 ? -3.847  -36.658 -15.186 1.000 37.963 0 228 LYS B CE  1 ? 
ATOM   3355 N NZ  . LYS B 1 193 ? -3.416  -35.929 -16.402 1.000 38.174 0 228 LYS B NZ  1 ? 
ATOM   3356 N N   . ASP B 1 194 ? -5.090  -37.806 -9.889  1.000 24.153 0 229 ASP B N   1 ? 
ATOM   3357 C CA  . ASP B 1 194 ? -5.120  -39.230 -9.598  1.000 27.024 0 229 ASP B CA  1 ? 
ATOM   3358 C C   . ASP B 1 194 ? -5.290  -39.489 -8.095  1.000 25.637 0 229 ASP B C   1 ? 
ATOM   3359 O O   . ASP B 1 194 ? -5.370  -40.640 -7.668  1.000 24.986 0 229 ASP B O   1 ? 
ATOM   3360 C CB  . ASP B 1 194 ? -3.887  -39.954 -10.165 1.000 31.978 0 229 ASP B CB  1 ? 
ATOM   3361 C CG  . ASP B 1 194 ? -3.830  -39.964 -11.694 1.000 39.344 0 229 ASP B CG  1 ? 
ATOM   3362 O OD1 . ASP B 1 194 ? -4.909  -40.078 -12.308 1.000 46.867 0 229 ASP B OD1 1 ? 
ATOM   3363 O OD2 . ASP B 1 194 ? -2.718  -39.845 -12.276 1.000 46.048 0 229 ASP B OD2 1 ? 
ATOM   3364 N N   . THR B 1 195 ? -5.379  -38.443 -7.270  1.000 22.599 0 230 THR B N   1 ? 
ATOM   3365 C CA  . THR B 1 195 ? -5.587  -38.654 -5.837  1.000 22.004 0 230 THR B CA  1 ? 
ATOM   3366 C C   . THR B 1 195 ? -7.039  -39.094 -5.563  1.000 21.249 0 230 THR B C   1 ? 
ATOM   3367 O O   . THR B 1 195 ? -7.980  -38.498 -6.073  1.000 19.426 0 230 THR B O   1 ? 
ATOM   3368 C CB  . THR B 1 195 ? -5.198  -37.403 -5.045  1.000 21.645 0 230 THR B CB  1 ? 
ATOM   3369 O OG1 . THR B 1 195 ? -3.813  -37.166 -5.299  1.000 21.105 0 230 THR B OG1 1 ? 
ATOM   3370 C CG2 . THR B 1 195 ? -5.431  -37.538 -3.555  1.000 21.398 0 230 THR B CG2 1 ? 
ATOM   3371 N N   . PRO B 1 196 ? -7.293  -40.170 -4.772  1.000 20.030 0 231 PRO B N   1 ? 
ATOM   3372 C CA  . PRO B 1 196 ? -8.648  -40.490 -4.317  1.000 19.835 0 231 PRO B CA  1 ? 
ATOM   3373 C C   . PRO B 1 196 ? -9.207  -39.340 -3.471  1.000 19.283 0 231 PRO B C   1 ? 
ATOM   3374 O O   . PRO B 1 196 ? -8.537  -38.865 -2.562  1.000 18.533 0 231 PRO B O   1 ? 
ATOM   3375 C CB  . PRO B 1 196 ? -8.451  -41.762 -3.477  1.000 19.790 0 231 PRO B CB  1 ? 
ATOM   3376 C CG  . PRO B 1 196 ? -7.209  -42.361 -4.035  1.000 19.824 0 231 PRO B CG  1 ? 
ATOM   3377 C CD  . PRO B 1 196 ? -6.320  -41.165 -4.293  1.000 20.363 0 231 PRO B CD  1 ? 
ATOM   3378 N N   . LYS B 1 197 ? -10.407 -38.857 -3.812  1.000 19.450 0 232 LYS B N   1 ? 
ATOM   3379 C CA  . LYS B 1 197 ? -10.910 -37.642 -3.192  1.000 20.888 0 232 LYS B CA  1 ? 
ATOM   3380 C C   . LYS B 1 197 ? -12.441 -37.592 -3.226  1.000 19.486 0 232 LYS B C   1 ? 
ATOM   3381 O O   . LYS B 1 197 ? -13.061 -38.074 -4.176  1.000 17.481 0 232 LYS B O   1 ? 
ATOM   3382 C CB  . LYS B 1 197 ? -10.288 -36.398 -3.842  1.000 21.957 0 232 LYS B CB  1 ? 
ATOM   3383 C CG  . LYS B 1 197 ? -10.428 -36.310 -5.355  1.000 25.679 0 232 LYS B CG  1 ? 
ATOM   3384 C CD  . LYS B 1 197 ? -9.861  -35.016 -5.917  1.000 30.270 0 232 LYS B CD  1 ? 
ATOM   3385 C CE  . LYS B 1 197 ? -9.895  -34.957 -7.429  1.000 35.701 0 232 LYS B CE  1 ? 
ATOM   3386 N NZ  . LYS B 1 197 ? -8.690  -35.602 -8.014  1.000 37.809 0 232 LYS B NZ  1 ? 
ATOM   3387 N N   . ILE B 1 198 ? -13.006 -36.998 -2.156  1.000 19.144 0 233 ILE B N   1 ? 
ATOM   3388 C CA  . ILE B 1 198 ? -14.407 -36.631 -2.057  1.000 20.293 0 233 ILE B CA  1 ? 
ATOM   3389 C C   . ILE B 1 198 ? -14.550 -35.170 -1.621  1.000 20.075 0 233 ILE B C   1 ? 
ATOM   3390 O O   . ILE B 1 198 ? -13.825 -34.680 -0.751  1.000 20.283 0 233 ILE B O   1 ? 
ATOM   3391 C CB  . ILE B 1 198 ? -15.156 -37.554 -1.075  1.000 20.697 0 233 ILE B CB  1 ? 
ATOM   3392 C CG1 . ILE B 1 198 ? -15.384 -38.949 -1.663  1.000 21.674 0 233 ILE B CG1 1 ? 
ATOM   3393 C CG2 . ILE B 1 198 ? -16.471 -36.907 -0.645  1.000 22.452 0 233 ILE B CG2 1 ? 
ATOM   3394 C CD1 . ILE B 1 198 ? -16.043 -39.910 -0.710  1.000 21.989 0 233 ILE B CD1 1 ? 
ATOM   3395 N N   . TYR B 1 199 ? -15.531 -34.508 -2.227  1.000 18.588 0 234 TYR B N   1 ? 
ATOM   3396 C CA  . TYR B 1 199 ? -16.039 -33.219 -1.789  1.000 18.341 0 234 TYR B CA  1 ? 
ATOM   3397 C C   . TYR B 1 199 ? -17.492 -33.436 -1.408  1.000 18.818 0 234 TYR B C   1 ? 
ATOM   3398 O O   . TYR B 1 199 ? -18.258 -33.909 -2.243  1.000 19.187 0 234 TYR B O   1 ? 
ATOM   3399 C CB  . TYR B 1 199 ? -15.927 -32.220 -2.937  1.000 18.174 0 234 TYR B CB  1 ? 
ATOM   3400 C CG  . TYR B 1 199 ? -16.571 -30.868 -2.737  1.000 18.449 0 234 TYR B CG  1 ? 
ATOM   3401 C CD1 . TYR B 1 199 ? -16.009 -29.898 -1.913  1.000 18.530 0 234 TYR B CD1 1 ? 
ATOM   3402 C CD2 . TYR B 1 199 ? -17.756 -30.554 -3.395  1.000 18.778 0 234 TYR B CD2 1 ? 
ATOM   3403 C CE1 . TYR B 1 199 ? -16.611 -28.656 -1.753  1.000 19.589 0 234 TYR B CE1 1 ? 
ATOM   3404 C CE2 . TYR B 1 199 ? -18.376 -29.318 -3.242  1.000 19.346 0 234 TYR B CE2 1 ? 
ATOM   3405 C CZ  . TYR B 1 199 ? -17.794 -28.364 -2.418  1.000 18.435 0 234 TYR B CZ  1 ? 
ATOM   3406 O OH  . TYR B 1 199 ? -18.342 -27.138 -2.267  1.000 18.880 0 234 TYR B OH  1 ? 
ATOM   3407 N N   . ALA B 1 200 ? -17.834 -33.209 -0.133  1.000 18.161 0 235 ALA B N   1 ? 
ATOM   3408 C CA  . ALA B 1 200 ? -19.184 -33.420 0.369   1.000 17.892 0 235 ALA B CA  1 ? 
ATOM   3409 C C   . ALA B 1 200 ? -19.613 -32.159 1.113   1.000 19.461 0 235 ALA B C   1 ? 
ATOM   3410 O O   . ALA B 1 200 ? -18.840 -31.657 1.914   1.000 20.581 0 235 ALA B O   1 ? 
ATOM   3411 C CB  . ALA B 1 200 ? -19.198 -34.616 1.288   1.000 17.082 0 235 ALA B CB  1 ? 
ATOM   3412 N N   . VAL B 1 201 ? -20.813 -31.636 0.847   1.000 19.292 0 236 VAL B N   1 ? 
ATOM   3413 C CA  . VAL B 1 201 ? -21.244 -30.403 1.484   1.000 20.317 0 236 VAL B CA  1 ? 
ATOM   3414 C C   . VAL B 1 201 ? -22.506 -30.706 2.283   1.000 19.459 0 236 VAL B C   1 ? 
ATOM   3415 O O   . VAL B 1 201 ? -23.489 -31.158 1.718   1.000 19.897 0 236 VAL B O   1 ? 
ATOM   3416 C CB  . VAL B 1 201 ? -21.453 -29.248 0.480   1.000 20.801 0 236 VAL B CB  1 ? 
ATOM   3417 C CG1 . VAL B 1 201 ? -21.979 -27.984 1.166   1.000 23.442 0 236 VAL B CG1 1 ? 
ATOM   3418 C CG2 . VAL B 1 201 ? -20.176 -28.916 -0.263  1.000 21.292 0 236 VAL B CG2 1 ? 
ATOM   3419 N N   . LEU B 1 202 ? -22.455 -30.425 3.589   1.000 18.798 0 237 LEU B N   1 ? 
ATOM   3420 C CA  . LEU B 1 202 ? -23.581 -30.618 4.488   1.000 18.397 0 237 LEU B CA  1 ? 
ATOM   3421 C C   . LEU B 1 202 ? -24.657 -29.570 4.196   1.000 18.991 0 237 LEU B C   1 ? 
ATOM   3422 O O   . LEU B 1 202 ? -24.382 -28.369 4.255   1.000 18.212 0 237 LEU B O   1 ? 
ATOM   3423 C CB  . LEU B 1 202 ? -23.074 -30.516 5.929   1.000 18.558 0 237 LEU B CB  1 ? 
ATOM   3424 C CG  . LEU B 1 202 ? -22.022 -31.540 6.363   1.000 18.419 0 237 LEU B CG  1 ? 
ATOM   3425 C CD1 . LEU B 1 202 ? -21.406 -31.176 7.705   1.000 18.096 0 237 LEU B CD1 1 ? 
ATOM   3426 C CD2 . LEU B 1 202 ? -22.630 -32.918 6.442   1.000 18.815 0 237 LEU B CD2 1 ? 
ATOM   3427 N N   . CYS B 1 203 ? -25.885 -30.024 3.894   1.000 19.452 0 238 CYS B N   1 ? 
ATOM   3428 C CA  . CYS B 1 203 ? -27.004 -29.121 3.654   1.000 21.810 0 238 CYS B CA  1 ? 
ATOM   3429 C C   . CYS B 1 203 ? -27.258 -28.266 4.879   1.000 22.469 0 238 CYS B C   1 ? 
ATOM   3430 O O   . CYS B 1 203 ? -27.315 -28.796 5.982   1.000 22.121 0 238 CYS B O   1 ? 
ATOM   3431 C CB  . CYS B 1 203 ? -28.336 -29.823 3.379   1.000 23.001 0 238 CYS B CB  1 ? 
ATOM   3432 S SG  . CYS B 1 203 ? -28.396 -30.658 1.776   1.000 32.476 0 238 CYS B SG  1 ? 
ATOM   3433 N N   . ASN B 1 204 ? -27.401 -26.955 4.656   1.000 27.408 0 239 ASN B N   1 ? 
ATOM   3434 C CA  . ASN B 1 204 ? -27.925 -26.050 5.659   1.000 34.658 0 239 ASN B CA  1 ? 
ATOM   3435 C C   . ASN B 1 204 ? -27.037 -25.983 6.916   1.000 34.386 0 239 ASN B C   1 ? 
ATOM   3436 O O   . ASN B 1 204 ? -27.522 -25.624 7.976   1.000 42.856 0 239 ASN B O   1 ? 
ATOM   3437 C CB  . ASN B 1 204 ? -29.352 -26.488 6.029   1.000 38.737 0 239 ASN B CB  1 ? 
ATOM   3438 C CG  . ASN B 1 204 ? -30.218 -25.343 6.488   1.000 45.284 0 239 ASN B CG  1 ? 
ATOM   3439 O OD1 . ASN B 1 204 ? -29.960 -24.190 6.136   1.000 49.114 0 239 ASN B OD1 1 ? 
ATOM   3440 N ND2 . ASN B 1 204 ? -31.253 -25.669 7.246   1.000 53.485 0 239 ASN B ND2 1 ? 
ATOM   3441 N N   . ALA B 1 205 ? -25.748 -26.340 6.833   1.000 28.504 0 240 ALA B N   1 ? 
ATOM   3442 C CA  . ALA B 1 205 ? -24.911 -26.409 8.019   1.000 23.238 0 240 ALA B CA  1 ? 
ATOM   3443 C C   . ALA B 1 205 ? -24.072 -25.143 8.119   1.000 20.787 0 240 ALA B C   1 ? 
ATOM   3444 O O   . ALA B 1 205 ? -23.761 -24.518 7.098   1.000 19.536 0 240 ALA B O   1 ? 
ATOM   3445 C CB  . ALA B 1 205 ? -24.034 -27.632 7.949   1.000 23.556 0 240 ALA B CB  1 ? 
ATOM   3446 N N   . SER B 1 206 ? -23.690 -24.807 9.353   1.000 17.480 0 241 SER B N   1 ? 
ATOM   3447 C CA  . SER B 1 206 ? -22.746 -23.743 9.637   1.000 16.689 0 241 SER B CA  1 ? 
ATOM   3448 C C   . SER B 1 206 ? -21.311 -24.288 9.677   1.000 15.480 0 241 SER B C   1 ? 
ATOM   3449 O O   . SER B 1 206 ? -21.091 -25.496 9.705   1.000 14.373 0 241 SER B O   1 ? 
ATOM   3450 C CB  . SER B 1 206 ? -23.052 -23.078 10.965  1.000 17.040 0 241 SER B CB  1 ? 
ATOM   3451 O OG  . SER B 1 206 ? -22.610 -23.904 12.044  1.000 15.963 0 241 SER B OG  1 ? 
ATOM   3452 N N   . HIS B 1 207 ? -20.365 -23.351 9.793   1.000 14.329 0 242 HIS B N   1 ? 
ATOM   3453 C CA  . HIS B 1 207 ? -18.950 -23.636 9.975   1.000 15.415 0 242 HIS B CA  1 ? 
ATOM   3454 C C   . HIS B 1 207 ? -18.697 -24.570 11.169  1.000 15.059 0 242 HIS B C   1 ? 
ATOM   3455 O O   . HIS B 1 207 ? -17.704 -25.315 11.165  1.000 15.560 0 242 HIS B O   1 ? 
ATOM   3456 C CB  . HIS B 1 207 ? -18.187 -22.312 10.101  1.000 14.858 0 242 HIS B CB  1 ? 
ATOM   3457 C CG  . HIS B 1 207 ? -16.705 -22.452 10.098  1.000 15.572 0 242 HIS B CG  1 ? 
ATOM   3458 N ND1 . HIS B 1 207 ? -15.998 -22.806 8.975   1.000 14.840 0 242 HIS B ND1 1 ? 
ATOM   3459 C CD2 . HIS B 1 207 ? -15.791 -22.273 11.076  1.000 16.458 0 242 HIS B CD2 1 ? 
ATOM   3460 C CE1 . HIS B 1 207 ? -14.703 -22.850 9.267   1.000 15.748 0 242 HIS B CE1 1 ? 
ATOM   3461 N NE2 . HIS B 1 207 ? -14.555 -22.551 10.534  1.000 15.567 0 242 HIS B NE2 1 ? 
ATOM   3462 N N   . ILE B 1 208 ? -19.583 -24.541 12.182  1.000 14.834 0 243 ILE B N   1 ? 
ATOM   3463 C CA  . ILE B 1 208 ? -19.321 -25.252 13.425  1.000 15.084 0 243 ILE B CA  1 ? 
ATOM   3464 C C   . ILE B 1 208 ? -20.188 -26.508 13.557  1.000 15.337 0 243 ILE B C   1 ? 
ATOM   3465 O O   . ILE B 1 208 ? -20.192 -27.135 14.616  1.000 14.112 0 243 ILE B O   1 ? 
ATOM   3466 C CB  . ILE B 1 208 ? -19.434 -24.315 14.641  1.000 15.137 0 243 ILE B CB  1 ? 
ATOM   3467 C CG1 . ILE B 1 208 ? -20.828 -23.690 14.778  1.000 16.006 0 243 ILE B CG1 1 ? 
ATOM   3468 C CG2 . ILE B 1 208 ? -18.326 -23.266 14.575  1.000 15.947 0 243 ILE B CG2 1 ? 
ATOM   3469 C CD1 . ILE B 1 208 ? -21.026 -22.900 16.077  1.000 16.939 0 243 ILE B CD1 1 ? 
ATOM   3470 N N   . ALA B 1 209 ? -20.828 -26.933 12.456  1.000 17.158 0 244 ALA B N   1 ? 
ATOM   3471 C CA  . ALA B 1 209 ? -21.461 -28.243 12.374  1.000 18.458 0 244 ALA B CA  1 ? 
ATOM   3472 C C   . ALA B 1 209 ? -20.533 -29.353 12.886  1.000 18.351 0 244 ALA B C   1 ? 
ATOM   3473 O O   . ALA B 1 209 ? -20.991 -30.284 13.566  1.000 20.635 0 244 ALA B O   1 ? 
ATOM   3474 C CB  . ALA B 1 209 ? -21.924 -28.519 10.956  1.000 19.117 0 244 ALA B CB  1 ? 
ATOM   3475 N N   . PRO B 1 210 ? -19.217 -29.337 12.567  1.000 17.938 0 245 PRO B N   1 ? 
ATOM   3476 C CA  . PRO B 1 210 ? -18.302 -30.370 13.069  1.000 17.504 0 245 PRO B CA  1 ? 
ATOM   3477 C C   . PRO B 1 210 ? -18.105 -30.487 14.576  1.000 17.031 0 245 PRO B C   1 ? 
ATOM   3478 O O   . PRO B 1 210 ? -17.627 -31.507 15.047  1.000 15.660 0 245 PRO B O   1 ? 
ATOM   3479 C CB  . PRO B 1 210 ? -16.983 -30.034 12.351  1.000 17.153 0 245 PRO B CB  1 ? 
ATOM   3480 C CG  . PRO B 1 210 ? -17.429 -29.347 11.076  1.000 17.084 0 245 PRO B CG  1 ? 
ATOM   3481 C CD  . PRO B 1 210 ? -18.579 -28.481 11.547  1.000 17.992 0 245 PRO B CD  1 ? 
ATOM   3482 N N   . ASN B 1 211 ? -18.516 -29.459 15.328  1.000 16.684 0 246 ASN B N   1 ? 
ATOM   3483 C CA  . ASN B 1 211 ? -18.357 -29.418 16.770  1.000 17.638 0 246 ASN B CA  1 ? 
ATOM   3484 C C   . ASN B 1 211 ? -19.524 -30.076 17.506  1.000 18.191 0 246 ASN B C   1 ? 
ATOM   3485 O O   . ASN B 1 211 ? -19.505 -30.112 18.725  1.000 18.131 0 246 ASN B O   1 ? 
ATOM   3486 C CB  . ASN B 1 211 ? -18.165 -27.967 17.250  1.000 16.852 0 246 ASN B CB  1 ? 
ATOM   3487 C CG  . ASN B 1 211 ? -16.913 -27.345 16.666  1.000 16.975 0 246 ASN B CG  1 ? 
ATOM   3488 O OD1 . ASN B 1 211 ? -16.937 -26.210 16.205  1.000 17.636 0 246 ASN B OD1 1 ? 
ATOM   3489 N ND2 . ASN B 1 211 ? -15.812 -28.084 16.679  1.000 17.711 0 246 ASN B ND2 1 ? 
ATOM   3490 N N   . SER B 1 212 ? -20.550 -30.514 16.781  1.000 18.443 0 247 SER B N   1 ? 
ATOM   3491 C CA  . SER B 1 212 ? -21.665 -31.267 17.338  1.000 19.981 0 247 SER B CA  1 ? 
ATOM   3492 C C   . SER B 1 212 ? -21.814 -32.596 16.595  1.000 20.143 0 247 SER B C   1 ? 
ATOM   3493 O O   . SER B 1 212 ? -21.601 -32.669 15.383  1.000 20.382 0 247 SER B O   1 ? 
ATOM   3494 C CB  . SER B 1 212 ? -22.973 -30.510 17.225  1.000 20.163 0 247 SER B CB  1 ? 
ATOM   3495 O OG  . SER B 1 212 ? -22.927 -29.305 17.924  1.000 24.531 0 247 SER B OG  1 ? 
ATOM   3496 N N   . ASN B 1 213 ? -22.280 -33.604 17.335  1.000 21.056 0 248 ASN B N   1 ? 
ATOM   3497 C CA  . ASN B 1 213 ? -22.540 -34.939 16.834  1.000 22.546 0 248 ASN B CA  1 ? 
ATOM   3498 C C   . ASN B 1 213 ? -23.311 -34.833 15.523  1.000 20.255 0 248 ASN B C   1 ? 
ATOM   3499 O O   . ASN B 1 213 ? -24.356 -34.215 15.486  1.000 19.423 0 248 ASN B O   1 ? 
ATOM   3500 C CB  . ASN B 1 213 ? -23.319 -35.739 17.882  1.000 28.165 0 248 ASN B CB  1 ? 
ATOM   3501 C CG  . ASN B 1 213 ? -23.807 -37.059 17.331  1.000 34.170 0 248 ASN B CG  1 ? 
ATOM   3502 O OD1 . ASN B 1 213 ? -22.999 -37.844 16.856  1.000 36.115 0 248 ASN B OD1 1 ? 
ATOM   3503 N ND2 . ASN B 1 213 ? -25.118 -37.268 17.295  1.000 42.004 0 248 ASN B ND2 1 ? 
ATOM   3504 N N   . ASN B 1 214 ? -22.782 -35.405 14.439  1.000 17.738 0 249 ASN B N   1 ? 
ATOM   3505 C CA  . ASN B 1 214 ? -23.321 -35.166 13.115  1.000 17.858 0 249 ASN B CA  1 ? 
ATOM   3506 C C   . ASN B 1 214 ? -23.324 -36.479 12.335  1.000 17.514 0 249 ASN B C   1 ? 
ATOM   3507 O O   . ASN B 1 214 ? -22.270 -37.084 12.150  1.000 17.623 0 249 ASN B O   1 ? 
ATOM   3508 C CB  . ASN B 1 214 ? -22.507 -34.077 12.413  1.000 17.983 0 249 ASN B CB  1 ? 
ATOM   3509 C CG  . ASN B 1 214 ? -23.044 -33.718 11.043  1.000 18.764 0 249 ASN B CG  1 ? 
ATOM   3510 O OD1 . ASN B 1 214 ? -22.947 -34.495 10.087  1.000 18.481 0 249 ASN B OD1 1 ? 
ATOM   3511 N ND2 . ASN B 1 214 ? -23.615 -32.529 10.952  1.000 17.658 0 249 ASN B ND2 1 ? 
ATOM   3512 N N   . ALA B 1 215 ? -24.504 -36.912 11.877  1.000 17.762 0 250 ALA B N   1 ? 
ATOM   3513 C CA  . ALA B 1 215 ? -24.661 -38.236 11.277  1.000 18.582 0 250 ALA B CA  1 ? 
ATOM   3514 C C   . ALA B 1 215 ? -23.813 -38.382 10.014  1.000 18.746 0 250 ALA B C   1 ? 
ATOM   3515 O O   . ALA B 1 215 ? -23.113 -39.374 9.855   1.000 19.639 0 250 ALA B O   1 ? 
ATOM   3516 C CB  . ALA B 1 215 ? -26.111 -38.523 10.976  1.000 19.782 0 250 ALA B CB  1 ? 
ATOM   3517 N N   . ALA B 1 216 ? -23.855 -37.390 9.122   1.000 19.391 0 251 ALA B N   1 ? 
ATOM   3518 C CA  . ALA B 1 216 ? -23.085 -37.461 7.885   1.000 18.566 0 251 ALA B CA  1 ? 
ATOM   3519 C C   . ALA B 1 216 ? -21.577 -37.514 8.151   1.000 17.591 0 251 ALA B C   1 ? 
ATOM   3520 O O   . ALA B 1 216 ? -20.849 -38.243 7.477   1.000 15.833 0 251 ALA B O   1 ? 
ATOM   3521 C CB  . ALA B 1 216 ? -23.440 -36.289 7.017   1.000 19.176 0 251 ALA B CB  1 ? 
ATOM   3522 N N   . ILE B 1 217 ? -21.098 -36.714 9.111   1.000 16.684 0 252 ILE B N   1 ? 
ATOM   3523 C CA  . ILE B 1 217 ? -19.674 -36.693 9.414   1.000 18.118 0 252 ILE B CA  1 ? 
ATOM   3524 C C   . ILE B 1 217 ? -19.250 -38.064 9.942   1.000 18.318 0 252 ILE B C   1 ? 
ATOM   3525 O O   . ILE B 1 217 ? -18.190 -38.547 9.577   1.000 18.891 0 252 ILE B O   1 ? 
ATOM   3526 C CB  . ILE B 1 217 ? -19.315 -35.550 10.390  1.000 17.655 0 252 ILE B CB  1 ? 
ATOM   3527 C CG1 . ILE B 1 217 ? -19.478 -34.209 9.688   1.000 17.610 0 252 ILE B CG1 1 ? 
ATOM   3528 C CG2 . ILE B 1 217 ? -17.913 -35.713 10.990  1.000 17.578 0 252 ILE B CG2 1 ? 
ATOM   3529 C CD1 . ILE B 1 217 ? -19.198 -33.024 10.568  1.000 19.458 0 252 ILE B CD1 1 ? 
ATOM   3530 N N   . LYS B 1 218 ? -20.076 -38.672 10.796  1.000 18.248 0 253 LYS B N   1 ? 
ATOM   3531 C CA  . LYS B 1 218 ? -19.834 -40.013 11.291  1.000 19.850 0 253 LYS B CA  1 ? 
ATOM   3532 C C   . LYS B 1 218 ? -19.749 -40.994 10.118  1.000 20.060 0 253 LYS B C   1 ? 
ATOM   3533 O O   . LYS B 1 218 ? -18.828 -41.810 10.051  1.000 18.534 0 253 LYS B O   1 ? 
ATOM   3534 C CB  . LYS B 1 218 ? -20.918 -40.422 12.294  1.000 21.625 0 253 LYS B CB  1 ? 
ATOM   3535 C CG  . LYS B 1 218 ? -20.845 -39.690 13.623  1.000 24.313 0 253 LYS B CG  1 ? 
ATOM   3536 C CD  . LYS B 1 218 ? -21.893 -40.104 14.636  1.000 28.049 0 253 LYS B CD  1 ? 
ATOM   3537 C CE  . LYS B 1 218 ? -23.275 -39.609 14.289  1.000 34.282 0 253 LYS B CE  1 ? 
ATOM   3538 N NZ  . LYS B 1 218 ? -24.271 -39.969 15.329  1.000 39.175 0 253 LYS B NZ  1 ? 
ATOM   3539 N N   . ILE B 1 219 ? -20.713 -40.938 9.199   1.000 18.501 0 254 ILE B N   1 ? 
ATOM   3540 C CA  . ILE B 1 219 ? -20.756 -41.906 8.107   1.000 20.817 0 254 ILE B CA  1 ? 
ATOM   3541 C C   . ILE B 1 219 ? -19.499 -41.793 7.239   1.000 20.698 0 254 ILE B C   1 ? 
ATOM   3542 O O   . ILE B 1 219 ? -18.830 -42.803 6.993   1.000 20.357 0 254 ILE B O   1 ? 
ATOM   3543 C CB  . ILE B 1 219 ? -22.049 -41.742 7.286   1.000 20.616 0 254 ILE B CB  1 ? 
ATOM   3544 C CG1 . ILE B 1 219 ? -23.262 -42.184 8.096   1.000 20.130 0 254 ILE B CG1 1 ? 
ATOM   3545 C CG2 . ILE B 1 219 ? -21.960 -42.443 5.923   1.000 21.786 0 254 ILE B CG2 1 ? 
ATOM   3546 C CD1 . ILE B 1 219 ? -24.553 -41.539 7.630   1.000 21.534 0 254 ILE B CD1 1 ? 
ATOM   3547 N N   . TYR B 1 220 ? -19.180 -40.571 6.802   1.000 18.487 0 255 TYR B N   1 ? 
ATOM   3548 C CA  . TYR B 1 220 ? -18.138 -40.363 5.809   1.000 18.475 0 255 TYR B CA  1 ? 
ATOM   3549 C C   . TYR B 1 220 ? -16.746 -40.500 6.425   1.000 17.960 0 255 TYR B C   1 ? 
ATOM   3550 O O   . TYR B 1 220 ? -15.871 -41.102 5.794   1.000 16.497 0 255 TYR B O   1 ? 
ATOM   3551 C CB  . TYR B 1 220 ? -18.393 -39.048 5.054   1.000 19.362 0 255 TYR B CB  1 ? 
ATOM   3552 C CG  . TYR B 1 220 ? -19.639 -39.150 4.219   1.000 21.286 0 255 TYR B CG  1 ? 
ATOM   3553 C CD1 . TYR B 1 220 ? -19.676 -40.019 3.137   1.000 23.889 0 255 TYR B CD1 1 ? 
ATOM   3554 C CD2 . TYR B 1 220 ? -20.795 -38.460 4.543   1.000 21.948 0 255 TYR B CD2 1 ? 
ATOM   3555 C CE1 . TYR B 1 220 ? -20.825 -40.201 2.391   1.000 24.421 0 255 TYR B CE1 1 ? 
ATOM   3556 C CE2 . TYR B 1 220 ? -21.951 -38.626 3.802   1.000 23.512 0 255 TYR B CE2 1 ? 
ATOM   3557 C CZ  . TYR B 1 220 ? -21.963 -39.496 2.721   1.000 24.447 0 255 TYR B CZ  1 ? 
ATOM   3558 O OH  . TYR B 1 220 ? -23.088 -39.722 1.976   1.000 25.453 0 255 TYR B OH  1 ? 
ATOM   3559 N N   . THR B 1 221 ? -16.542 -40.007 7.662   1.000 16.347 0 256 THR B N   1 ? 
ATOM   3560 C CA  A THR B 1 221 ? -15.230 -40.070 8.283   0.500 16.979 0 256 THR B CA  1 ? 
ATOM   3561 C CA  B THR B 1 221 ? -15.236 -40.076 8.309   0.500 16.164 0 256 THR B CA  1 ? 
ATOM   3562 C C   . THR B 1 221 ? -14.880 -41.523 8.632   1.000 16.500 0 256 THR B C   1 ? 
ATOM   3563 O O   . THR B 1 221 ? -13.770 -41.978 8.337   1.000 16.587 0 256 THR B O   1 ? 
ATOM   3564 C CB  A THR B 1 221 ? -15.176 -39.063 9.445   0.500 17.664 0 256 THR B CB  1 ? 
ATOM   3565 C CB  B THR B 1 221 ? -15.110 -39.260 9.613   0.500 15.657 0 256 THR B CB  1 ? 
ATOM   3566 O OG1 A THR B 1 221 ? -15.659 -37.811 8.931   0.500 17.075 0 256 THR B OG1 1 ? 
ATOM   3567 O OG1 B THR B 1 221 ? -16.018 -39.719 10.615  0.500 14.257 0 256 THR B OG1 1 ? 
ATOM   3568 C CG2 A THR B 1 221 ? -13.795 -38.869 10.024  0.500 18.045 0 256 THR B CG2 1 ? 
ATOM   3569 C CG2 B THR B 1 221 ? -15.306 -37.774 9.396   0.500 15.564 0 256 THR B CG2 1 ? 
ATOM   3570 N N   . VAL B 1 222 ? -15.811 -42.255 9.248   1.000 16.447 0 257 VAL B N   1 ? 
ATOM   3571 C CA  . VAL B 1 222 ? -15.558 -43.651 9.592   1.000 17.541 0 257 VAL B CA  1 ? 
ATOM   3572 C C   . VAL B 1 222 ? -15.268 -44.448 8.321   1.000 17.319 0 257 VAL B C   1 ? 
ATOM   3573 O O   . VAL B 1 222 ? -14.297 -45.204 8.280   1.000 16.163 0 257 VAL B O   1 ? 
ATOM   3574 C CB  . VAL B 1 222 ? -16.692 -44.303 10.418  1.000 17.970 0 257 VAL B CB  1 ? 
ATOM   3575 C CG1 . VAL B 1 222 ? -16.518 -45.807 10.540  1.000 19.695 0 257 VAL B CG1 1 ? 
ATOM   3576 C CG2 . VAL B 1 222 ? -16.787 -43.708 11.812  1.000 18.789 0 257 VAL B CG2 1 ? 
ATOM   3577 N N   . SER B 1 223 ? -16.095 -44.277 7.285   1.000 16.712 0 258 SER B N   1 ? 
ATOM   3578 C CA  . SER B 1 223 ? -15.925 -45.032 6.046   1.000 18.141 0 258 SER B CA  1 ? 
ATOM   3579 C C   . SER B 1 223 ? -14.587 -44.713 5.378   1.000 18.383 0 258 SER B C   1 ? 
ATOM   3580 O O   . SER B 1 223 ? -13.873 -45.617 4.931   1.000 20.732 0 258 SER B O   1 ? 
ATOM   3581 C CB  . SER B 1 223 ? -17.061 -44.788 5.096   1.000 17.814 0 258 SER B CB  1 ? 
ATOM   3582 O OG  . SER B 1 223 ? -18.271 -45.202 5.689   1.000 18.127 0 258 SER B OG  1 ? 
ATOM   3583 N N   . TRP B 1 224 ? -14.245 -43.428 5.304   1.000 17.245 0 259 TRP B N   1 ? 
ATOM   3584 C CA  . TRP B 1 224 ? -12.983 -43.023 4.704   1.000 17.493 0 259 TRP B CA  1 ? 
ATOM   3585 C C   . TRP B 1 224 ? -11.782 -43.648 5.423   1.000 17.622 0 259 TRP B C   1 ? 
ATOM   3586 O O   . TRP B 1 224 ? -10.877 -44.167 4.778   1.000 17.195 0 259 TRP B O   1 ? 
ATOM   3587 C CB  . TRP B 1 224 ? -12.874 -41.502 4.712   1.000 17.500 0 259 TRP B CB  1 ? 
ATOM   3588 C CG  . TRP B 1 224 ? -11.874 -40.956 3.749   1.000 16.899 0 259 TRP B CG  1 ? 
ATOM   3589 C CD1 . TRP B 1 224 ? -10.688 -40.356 4.055   1.000 16.800 0 259 TRP B CD1 1 ? 
ATOM   3590 C CD2 . TRP B 1 224 ? -12.018 -40.879 2.325   1.000 17.482 0 259 TRP B CD2 1 ? 
ATOM   3591 N NE1 . TRP B 1 224 ? -10.076 -39.933 2.909   1.000 17.640 0 259 TRP B NE1 1 ? 
ATOM   3592 C CE2 . TRP B 1 224 ? -10.877 -40.218 1.833   1.000 16.756 0 259 TRP B CE2 1 ? 
ATOM   3593 C CE3 . TRP B 1 224 ? -13.022 -41.245 1.422   1.000 17.565 0 259 TRP B CE3 1 ? 
ATOM   3594 C CZ2 . TRP B 1 224 ? -10.687 -39.970 0.472   1.000 17.068 0 259 TRP B CZ2 1 ? 
ATOM   3595 C CZ3 . TRP B 1 224 ? -12.829 -41.012 0.075   1.000 17.064 0 259 TRP B CZ3 1 ? 
ATOM   3596 C CH2 . TRP B 1 224 ? -11.676 -40.377 -0.392  1.000 16.353 0 259 TRP B CH2 1 ? 
ATOM   3597 N N   . PHE B 1 225 ? -11.746 -43.540 6.755   1.000 16.874 0 260 PHE B N   1 ? 
ATOM   3598 C CA  . PHE B 1 225 ? -10.623 -44.047 7.520   1.000 17.734 0 260 PHE B CA  1 ? 
ATOM   3599 C C   . PHE B 1 225 ? -10.606 -45.574 7.481   1.000 17.423 0 260 PHE B C   1 ? 
ATOM   3600 O O   . PHE B 1 225 ? -9.542  -46.171 7.421   1.000 17.518 0 260 PHE B O   1 ? 
ATOM   3601 C CB  . PHE B 1 225 ? -10.648 -43.504 8.943   1.000 18.547 0 260 PHE B CB  1 ? 
ATOM   3602 C CG  . PHE B 1 225 ? -10.230 -42.054 9.073   1.000 19.123 0 260 PHE B CG  1 ? 
ATOM   3603 C CD1 . PHE B 1 225 ? -9.012  -41.621 8.591   1.000 18.986 0 260 PHE B CD1 1 ? 
ATOM   3604 C CD2 . PHE B 1 225 ? -11.047 -41.133 9.717   1.000 18.392 0 260 PHE B CD2 1 ? 
ATOM   3605 C CE1 . PHE B 1 225 ? -8.618  -40.301 8.742   1.000 19.513 0 260 PHE B CE1 1 ? 
ATOM   3606 C CE2 . PHE B 1 225 ? -10.638 -39.823 9.891   1.000 19.838 0 260 PHE B CE2 1 ? 
ATOM   3607 C CZ  . PHE B 1 225 ? -9.427  -39.406 9.403   1.000 19.057 0 260 PHE B CZ  1 ? 
ATOM   3608 N N   . LYS B 1 226 ? -11.772 -46.211 7.491   1.000 17.422 0 261 LYS B N   1 ? 
ATOM   3609 C CA  . LYS B 1 226 ? -11.815 -47.663 7.349   1.000 19.240 0 261 LYS B CA  1 ? 
ATOM   3610 C C   . LYS B 1 226 ? -11.299 -48.124 5.988   1.000 19.720 0 261 LYS B C   1 ? 
ATOM   3611 O O   . LYS B 1 226 ? -10.521 -49.091 5.902   1.000 19.056 0 261 LYS B O   1 ? 
ATOM   3612 C CB  . LYS B 1 226 ? -13.229 -48.186 7.603   1.000 20.562 0 261 LYS B CB  1 ? 
ATOM   3613 C CG  . LYS B 1 226 ? -13.571 -48.275 9.079   1.000 20.478 0 261 LYS B CG  1 ? 
ATOM   3614 C CD  . LYS B 1 226 ? -13.053 -49.530 9.708   1.000 20.697 0 261 LYS B CD  1 ? 
ATOM   3615 C CE  . LYS B 1 226 ? -13.447 -49.623 11.169  1.000 21.249 0 261 LYS B CE  1 ? 
ATOM   3616 N NZ  . LYS B 1 226 ? -12.909 -50.857 11.784  1.000 21.995 0 261 LYS B NZ  1 ? 
ATOM   3617 N N   . LEU B 1 227 ? -11.713 -47.430 4.920   1.000 18.566 0 262 LEU B N   1 ? 
ATOM   3618 C CA  . LEU B 1 227 ? -11.307 -47.858 3.590   1.000 18.460 0 262 LEU B CA  1 ? 
ATOM   3619 C C   . LEU B 1 227 ? -9.805  -47.656 3.397   1.000 19.083 0 262 LEU B C   1 ? 
ATOM   3620 O O   . LEU B 1 227 ? -9.116  -48.524 2.852   1.000 18.836 0 262 LEU B O   1 ? 
ATOM   3621 C CB  . LEU B 1 227 ? -12.108 -47.086 2.536   1.000 18.390 0 262 LEU B CB  1 ? 
ATOM   3622 C CG  . LEU B 1 227 ? -11.758 -47.440 1.086   1.000 19.315 0 262 LEU B CG  1 ? 
ATOM   3623 C CD1 . LEU B 1 227 ? -12.080 -48.895 0.785   1.000 19.456 0 262 LEU B CD1 1 ? 
ATOM   3624 C CD2 . LEU B 1 227 ? -12.468 -46.543 0.086   1.000 19.436 0 262 LEU B CD2 1 ? 
ATOM   3625 N N   . PHE B 1 228 ? -9.293  -46.500 3.843   1.000 18.341 0 263 PHE B N   1 ? 
ATOM   3626 C CA  . PHE B 1 228 ? -7.939  -46.088 3.503   1.000 18.917 0 263 PHE B CA  1 ? 
ATOM   3627 C C   . PHE B 1 228 ? -6.921  -46.449 4.578   1.000 19.600 0 263 PHE B C   1 ? 
ATOM   3628 O O   . PHE B 1 228 ? -5.796  -46.760 4.223   1.000 22.709 0 263 PHE B O   1 ? 
ATOM   3629 C CB  . PHE B 1 228 ? -7.929  -44.612 3.133   1.000 17.608 0 263 PHE B CB  1 ? 
ATOM   3630 C CG  . PHE B 1 228 ? -8.557  -44.384 1.789   1.000 17.835 0 263 PHE B CG  1 ? 
ATOM   3631 C CD1 . PHE B 1 228 ? -7.972  -44.915 0.644   1.000 19.529 0 263 PHE B CD1 1 ? 
ATOM   3632 C CD2 . PHE B 1 228 ? -9.776  -43.753 1.668   1.000 18.033 0 263 PHE B CD2 1 ? 
ATOM   3633 C CE1 . PHE B 1 228 ? -8.546  -44.717 -0.600  1.000 19.036 0 263 PHE B CE1 1 ? 
ATOM   3634 C CE2 . PHE B 1 228 ? -10.351 -43.578 0.420   1.000 18.893 0 263 PHE B CE2 1 ? 
ATOM   3635 C CZ  . PHE B 1 228 ? -9.737  -44.052 -0.713  1.000 18.421 0 263 PHE B CZ  1 ? 
ATOM   3636 N N   . LEU B 1 229 ? -7.293  -46.420 5.865   1.000 21.105 0 264 LEU B N   1 ? 
ATOM   3637 C CA  . LEU B 1 229 ? -6.348  -46.776 6.918   1.000 20.266 0 264 LEU B CA  1 ? 
ATOM   3638 C C   . LEU B 1 229 ? -6.336  -48.286 7.104   1.000 19.386 0 264 LEU B C   1 ? 
ATOM   3639 O O   . LEU B 1 229 ? -5.278  -48.848 7.350   1.000 20.266 0 264 LEU B O   1 ? 
ATOM   3640 C CB  . LEU B 1 229 ? -6.678  -46.077 8.239   1.000 19.630 0 264 LEU B CB  1 ? 
ATOM   3641 C CG  . LEU B 1 229 ? -6.593  -44.549 8.237   1.000 20.493 0 264 LEU B CG  1 ? 
ATOM   3642 C CD1 . LEU B 1 229 ? -6.626  -43.981 9.660   1.000 19.902 0 264 LEU B CD1 1 ? 
ATOM   3643 C CD2 . LEU B 1 229 ? -5.354  -44.066 7.525   1.000 19.938 0 264 LEU B CD2 1 ? 
ATOM   3644 N N   . CYS B 1 230 ? -7.495  -48.928 6.977   1.000 20.214 0 265 CYS B N   1 ? 
ATOM   3645 C CA  . CYS B 1 230 ? -7.600  -50.345 7.286   1.000 21.298 0 265 CYS B CA  1 ? 
ATOM   3646 C C   . CYS B 1 230 ? -7.689  -51.196 6.025   1.000 22.901 0 265 CYS B C   1 ? 
ATOM   3647 O O   . CYS B 1 230 ? -7.696  -52.406 6.155   1.000 21.722 0 265 CYS B O   1 ? 
ATOM   3648 C CB  . CYS B 1 230 ? -8.839  -50.670 8.105   1.000 20.717 0 265 CYS B CB  1 ? 
ATOM   3649 S SG  . CYS B 1 230 ? -8.999  -49.686 9.609   1.000 23.987 0 265 CYS B SG  1 ? 
ATOM   3650 N N   . ASP B 1 231 ? -7.820  -50.580 4.849   1.000 22.899 0 266 ASP B N   1 ? 
ATOM   3651 C CA  . ASP B 1 231 ? -8.097  -51.299 3.613   1.000 27.687 0 266 ASP B CA  1 ? 
ATOM   3652 C C   . ASP B 1 231 ? -9.349  -52.163 3.748   1.000 28.275 0 266 ASP B C   1 ? 
ATOM   3653 O O   . ASP B 1 231 ? -9.407  -53.249 3.173   1.000 25.919 0 266 ASP B O   1 ? 
ATOM   3654 C CB  . ASP B 1 231 ? -6.912  -52.163 3.153   1.000 30.837 0 266 ASP B CB  1 ? 
ATOM   3655 C CG  . ASP B 1 231 ? -5.658  -51.344 2.874   1.000 34.904 0 266 ASP B CG  1 ? 
ATOM   3656 O OD1 . ASP B 1 231 ? -5.744  -50.363 2.105   1.000 37.750 0 266 ASP B OD1 1 ? 
ATOM   3657 O OD2 . ASP B 1 231 ? -4.609  -51.674 3.448   1.000 41.461 0 266 ASP B OD2 1 ? 
ATOM   3658 N N   . ASP B 1 232 ? -10.353 -51.672 4.484   1.000 25.460 0 267 ASP B N   1 ? 
ATOM   3659 C CA  . ASP B 1 232 ? -11.592 -52.407 4.648   1.000 23.053 0 267 ASP B CA  1 ? 
ATOM   3660 C C   . ASP B 1 232 ? -12.562 -51.982 3.545   1.000 23.023 0 267 ASP B C   1 ? 
ATOM   3661 O O   . ASP B 1 232 ? -13.227 -50.954 3.653   1.000 20.768 0 267 ASP B O   1 ? 
ATOM   3662 C CB  . ASP B 1 232 ? -12.139 -52.226 6.063   1.000 24.256 0 267 ASP B CB  1 ? 
ATOM   3663 C CG  . ASP B 1 232 ? -13.227 -53.217 6.422   1.000 24.277 0 267 ASP B CG  1 ? 
ATOM   3664 O OD1 . ASP B 1 232 ? -13.795 -53.797 5.480   1.000 24.009 0 267 ASP B OD1 1 ? 
ATOM   3665 O OD2 . ASP B 1 232 ? -13.463 -53.430 7.646   1.000 25.250 0 267 ASP B OD2 1 ? 
ATOM   3666 N N   . THR B 1 233 ? -12.642 -52.796 2.483   1.000 23.190 0 268 THR B N   1 ? 
ATOM   3667 C CA  . THR B 1 233 ? -13.368 -52.440 1.278   1.000 24.344 0 268 THR B CA  1 ? 
ATOM   3668 C C   . THR B 1 233 ? -14.868 -52.670 1.470   1.000 24.488 0 268 THR B C   1 ? 
ATOM   3669 O O   . THR B 1 233 ? -15.668 -52.305 0.612   1.000 26.412 0 268 THR B O   1 ? 
ATOM   3670 C CB  . THR B 1 233 ? -12.836 -53.210 0.054   1.000 27.152 0 268 THR B CB  1 ? 
ATOM   3671 O OG1 . THR B 1 233 ? -12.903 -54.603 0.335   1.000 28.629 0 268 THR B OG1 1 ? 
ATOM   3672 C CG2 . THR B 1 233 ? -11.403 -52.893 -0.302  1.000 27.959 0 268 THR B CG2 1 ? 
ATOM   3673 N N   . ARG B 1 234 ? -15.290 -53.210 2.621   1.000 25.717 0 269 ARG B N   1 ? 
ATOM   3674 C CA  . ARG B 1 234 ? -16.709 -53.250 2.949   1.000 22.554 0 269 ARG B CA  1 ? 
ATOM   3675 C C   . ARG B 1 234 ? -17.304 -51.855 3.173   1.000 22.815 0 269 ARG B C   1 ? 
ATOM   3676 O O   . ARG B 1 234 ? -18.539 -51.695 3.223   1.000 22.437 0 269 ARG B O   1 ? 
ATOM   3677 C CB  . ARG B 1 234 ? -16.928 -54.071 4.219   1.000 24.598 0 269 ARG B CB  1 ? 
ATOM   3678 C CG  . ARG B 1 234 ? -16.490 -55.526 4.102   1.000 26.594 0 269 ARG B CG  1 ? 
ATOM   3679 C CD  . ARG B 1 234 ? -16.650 -56.262 5.435   1.000 26.606 0 269 ARG B CD  1 ? 
ATOM   3680 N NE  . ARG B 1 234 ? -15.805 -55.730 6.499   1.000 26.000 0 269 ARG B NE  1 ? 
ATOM   3681 C CZ  . ARG B 1 234 ? -15.856 -56.111 7.774   1.000 27.192 0 269 ARG B CZ  1 ? 
ATOM   3682 N NH1 . ARG B 1 234 ? -16.693 -57.056 8.165   1.000 27.348 0 269 ARG B NH1 1 ? 
ATOM   3683 N NH2 . ARG B 1 234 ? -15.080 -55.527 8.666   1.000 27.521 0 269 ARG B NH2 1 ? 
ATOM   3684 N N   . TYR B 1 235 ? -16.442 -50.835 3.349   1.000 20.972 0 270 TYR B N   1 ? 
ATOM   3685 C CA  . TYR B 1 235 ? -16.920 -49.473 3.579   1.000 21.131 0 270 TYR B CA  1 ? 
ATOM   3686 C C   . TYR B 1 235 ? -17.009 -48.680 2.278   1.000 22.254 0 270 TYR B C   1 ? 
ATOM   3687 O O   . TYR B 1 235 ? -17.542 -47.572 2.282   1.000 21.150 0 270 TYR B O   1 ? 
ATOM   3688 C CB  . TYR B 1 235 ? -16.019 -48.766 4.594   1.000 19.211 0 270 TYR B CB  1 ? 
ATOM   3689 C CG  . TYR B 1 235 ? -16.185 -49.297 5.988   1.000 18.471 0 270 TYR B CG  1 ? 
ATOM   3690 C CD1 . TYR B 1 235 ? -15.619 -50.504 6.376   1.000 18.260 0 270 TYR B CD1 1 ? 
ATOM   3691 C CD2 . TYR B 1 235 ? -16.993 -48.633 6.893   1.000 18.144 0 270 TYR B CD2 1 ? 
ATOM   3692 C CE1 . TYR B 1 235 ? -15.787 -51.002 7.662   1.000 19.164 0 270 TYR B CE1 1 ? 
ATOM   3693 C CE2 . TYR B 1 235 ? -17.167 -49.110 8.181   1.000 18.648 0 270 TYR B CE2 1 ? 
ATOM   3694 C CZ  . TYR B 1 235 ? -16.567 -50.297 8.569   1.000 18.903 0 270 TYR B CZ  1 ? 
ATOM   3695 O OH  . TYR B 1 235 ? -16.783 -50.709 9.857   1.000 17.704 0 270 TYR B OH  1 ? 
ATOM   3696 N N   . ARG B 1 236 ? -16.516 -49.252 1.167   1.000 23.778 0 271 ARG B N   1 ? 
ATOM   3697 C CA  . ARG B 1 236 ? -16.522 -48.548 -0.106  1.000 24.343 0 271 ARG B CA  1 ? 
ATOM   3698 C C   . ARG B 1 236 ? -17.954 -48.198 -0.504  1.000 24.322 0 271 ARG B C   1 ? 
ATOM   3699 O O   . ARG B 1 236 ? -18.191 -47.165 -1.127  1.000 22.889 0 271 ARG B O   1 ? 
ATOM   3700 C CB  . ARG B 1 236 ? -15.851 -49.356 -1.226  1.000 26.981 0 271 ARG B CB  1 ? 
ATOM   3701 C CG  . ARG B 1 236 ? -15.086 -48.484 -2.220  1.000 31.677 0 271 ARG B CG  1 ? 
ATOM   3702 C CD  . ARG B 1 236 ? -14.786 -49.100 -3.576  1.000 33.863 0 271 ARG B CD  1 ? 
ATOM   3703 N NE  . ARG B 1 236 ? -14.384 -50.487 -3.462  1.000 35.512 0 271 ARG B NE  1 ? 
ATOM   3704 C CZ  . ARG B 1 236 ? -13.137 -50.892 -3.270  1.000 37.429 0 271 ARG B CZ  1 ? 
ATOM   3705 N NH1 . ARG B 1 236 ? -12.838 -52.174 -3.405  1.000 35.870 0 271 ARG B NH1 1 ? 
ATOM   3706 N NH2 . ARG B 1 236 ? -12.179 -50.009 -3.043  1.000 36.234 0 271 ARG B NH2 1 ? 
ATOM   3707 N N   . LYS B 1 237 ? -18.913 -49.063 -0.156  1.000 24.010 0 272 LYS B N   1 ? 
ATOM   3708 C CA  . LYS B 1 237 ? -20.307 -48.876 -0.524  1.000 25.497 0 272 LYS B CA  1 ? 
ATOM   3709 C C   . LYS B 1 237 ? -20.874 -47.543 -0.005  1.000 25.923 0 272 LYS B C   1 ? 
ATOM   3710 O O   . LYS B 1 237 ? -21.801 -47.004 -0.592  1.000 26.047 0 272 LYS B O   1 ? 
ATOM   3711 C CB  . LYS B 1 237 ? -21.155 -50.042 -0.006  1.000 27.259 0 272 LYS B CB  1 ? 
ATOM   3712 C CG  . LYS B 1 237 ? -21.275 -50.136 1.509   1.000 31.430 0 272 LYS B CG  1 ? 
ATOM   3713 C CD  . LYS B 1 237 ? -22.137 -51.281 2.038   1.000 33.285 0 272 LYS B CD  1 ? 
ATOM   3714 C CE  . LYS B 1 237 ? -21.794 -52.650 1.493   1.000 37.994 0 272 LYS B CE  1 ? 
ATOM   3715 N NZ  . LYS B 1 237 ? -20.420 -53.111 1.824   1.000 39.925 0 272 LYS B NZ  1 ? 
ATOM   3716 N N   . PHE B 1 238 ? -20.364 -47.012 1.108   1.000 22.858 0 273 PHE B N   1 ? 
ATOM   3717 C CA  . PHE B 1 238 ? -20.896 -45.776 1.656   1.000 22.652 0 273 PHE B CA  1 ? 
ATOM   3718 C C   . PHE B 1 238 ? -20.357 -44.580 0.867   1.000 22.598 0 273 PHE B C   1 ? 
ATOM   3719 O O   . PHE B 1 238 ? -20.886 -43.478 0.992   1.000 25.117 0 273 PHE B O   1 ? 
ATOM   3720 C CB  . PHE B 1 238 ? -20.577 -45.690 3.152   1.000 23.549 0 273 PHE B CB  1 ? 
ATOM   3721 C CG  . PHE B 1 238 ? -21.099 -46.865 3.951   1.000 22.663 0 273 PHE B CG  1 ? 
ATOM   3722 C CD1 . PHE B 1 238 ? -22.466 -47.052 4.134   1.000 24.238 0 273 PHE B CD1 1 ? 
ATOM   3723 C CD2 . PHE B 1 238 ? -20.227 -47.794 4.492   1.000 21.655 0 273 PHE B CD2 1 ? 
ATOM   3724 C CE1 . PHE B 1 238 ? -22.944 -48.151 4.840   1.000 24.767 0 273 PHE B CE1 1 ? 
ATOM   3725 C CE2 . PHE B 1 238 ? -20.700 -48.883 5.205   1.000 21.620 0 273 PHE B CE2 1 ? 
ATOM   3726 C CZ  . PHE B 1 238 ? -22.055 -49.067 5.374   1.000 22.455 0 273 PHE B CZ  1 ? 
ATOM   3727 N N   . LEU B 1 239 ? -19.304 -44.801 0.070   1.000 20.554 0 274 LEU B N   1 ? 
ATOM   3728 C CA  . LEU B 1 239 ? -18.565 -43.722 -0.587  1.000 22.080 0 274 LEU B CA  1 ? 
ATOM   3729 C C   . LEU B 1 239 ? -18.841 -43.690 -2.093  1.000 23.417 0 274 LEU B C   1 ? 
ATOM   3730 O O   . LEU B 1 239 ? -18.335 -42.803 -2.793  1.000 23.526 0 274 LEU B O   1 ? 
ATOM   3731 C CB  . LEU B 1 239 ? -17.070 -43.920 -0.324  1.000 20.273 0 274 LEU B CB  1 ? 
ATOM   3732 C CG  . LEU B 1 239 ? -16.677 -44.030 1.148   1.000 21.376 0 274 LEU B CG  1 ? 
ATOM   3733 C CD1 . LEU B 1 239 ? -15.196 -44.321 1.284   1.000 22.425 0 274 LEU B CD1 1 ? 
ATOM   3734 C CD2 . LEU B 1 239 ? -17.044 -42.760 1.905   1.000 20.124 0 274 LEU B CD2 1 ? 
ATOM   3735 N N   . CYS B 1 240 ? -19.659 -44.657 -2.551  1.000 23.835 0 275 CYS B N   1 ? 
ATOM   3736 C CA  . CYS B 1 240 ? -19.935 -44.924 -3.953  1.000 28.169 0 275 CYS B CA  1 ? 
ATOM   3737 C C   . CYS B 1 240 ? -21.439 -44.833 -4.184  1.000 28.699 0 275 CYS B C   1 ? 
ATOM   3738 O O   . CYS B 1 240 ? -22.213 -45.175 -3.302  1.000 30.281 0 275 CYS B O   1 ? 
ATOM   3739 C CB  . CYS B 1 240 ? -19.431 -46.306 -4.362  1.000 29.989 0 275 CYS B CB  1 ? 
ATOM   3740 S SG  . CYS B 1 240 ? -17.622 -46.424 -4.349  1.000 33.723 0 275 CYS B SG  1 ? 
ATOM   3741 N N   . ASN B 1 241 ? -21.833 -44.346 -5.367  1.000 31.765 0 276 ASN B N   1 ? 
ATOM   3742 C CA  . ASN B 1 241 ? -23.241 -44.199 -5.727  1.000 32.646 0 276 ASN B CA  1 ? 
ATOM   3743 C C   . ASN B 1 241 ? -23.969 -43.411 -4.641  1.000 32.089 0 276 ASN B C   1 ? 
ATOM   3744 O O   . ASN B 1 241 ? -25.044 -43.809 -4.211  1.000 29.307 0 276 ASN B O   1 ? 
ATOM   3745 C CB  . ASN B 1 241 ? -23.944 -45.541 -5.915  1.000 32.202 0 276 ASN B CB  1 ? 
ATOM   3746 C CG  . ASN B 1 241 ? -23.137 -46.493 -6.773  1.000 37.610 0 276 ASN B CG  1 ? 
ATOM   3747 O OD1 . ASN B 1 241 ? -22.779 -46.173 -7.905  1.000 37.469 0 276 ASN B OD1 1 ? 
ATOM   3748 N ND2 . ASN B 1 241 ? -22.797 -47.649 -6.224  1.000 42.531 0 276 ASN B ND2 1 ? 
ATOM   3749 N N   . VAL B 1 242 ? -23.348 -42.320 -4.188  1.000 31.205 0 277 VAL B N   1 ? 
ATOM   3750 C CA  . VAL B 1 242 ? -23.834 -41.604 -3.029  1.000 31.567 0 277 VAL B CA  1 ? 
ATOM   3751 C C   . VAL B 1 242 ? -25.006 -40.732 -3.468  1.000 37.402 0 277 VAL B C   1 ? 
ATOM   3752 O O   . VAL B 1 242 ? -24.870 -39.872 -4.341  1.000 40.735 0 277 VAL B O   1 ? 
ATOM   3753 C CB  . VAL B 1 242 ? -22.734 -40.757 -2.381  1.000 30.831 0 277 VAL B CB  1 ? 
ATOM   3754 C CG1 . VAL B 1 242 ? -23.290 -39.887 -1.278  1.000 29.035 0 277 VAL B CG1 1 ? 
ATOM   3755 C CG2 . VAL B 1 242 ? -21.587 -41.611 -1.864  1.000 30.713 0 277 VAL B CG2 1 ? 
ATOM   3756 N N   . ASN B 1 243 ? -26.159 -40.963 -2.849  1.000 36.656 0 278 ASN B N   1 ? 
ATOM   3757 C CA  . ASN B 1 243 ? -27.320 -40.130 -3.083  1.000 39.832 0 278 ASN B CA  1 ? 
ATOM   3758 C C   . ASN B 1 243 ? -27.891 -39.828 -1.703  1.000 39.888 0 278 ASN B C   1 ? 
ATOM   3759 O O   . ASN B 1 243 ? -28.764 -40.539 -1.227  1.000 46.456 0 278 ASN B O   1 ? 
ATOM   3760 C CB  . ASN B 1 243 ? -28.267 -40.846 -4.049  1.000 44.411 0 278 ASN B CB  1 ? 
ATOM   3761 C CG  . ASN B 1 243 ? -29.520 -40.065 -4.365  1.000 49.730 0 278 ASN B CG  1 ? 
ATOM   3762 O OD1 . ASN B 1 243 ? -29.655 -38.904 -3.979  1.000 56.196 0 278 ASN B OD1 1 ? 
ATOM   3763 N ND2 . ASN B 1 243 ? -30.448 -40.713 -5.049  1.000 56.081 0 278 ASN B ND2 1 ? 
ATOM   3764 N N   . ASP B 1 244 ? -27.332 -38.805 -1.051  1.000 36.201 0 279 ASP B N   1 ? 
ATOM   3765 C CA  . ASP B 1 244 ? -27.486 -38.612 0.376   1.000 29.562 0 279 ASP B CA  1 ? 
ATOM   3766 C C   . ASP B 1 244 ? -28.167 -37.270 0.622   1.000 27.010 0 279 ASP B C   1 ? 
ATOM   3767 O O   . ASP B 1 244 ? -27.590 -36.214 0.342   1.000 24.125 0 279 ASP B O   1 ? 
ATOM   3768 C CB  . ASP B 1 244 ? -26.130 -38.702 1.073   1.000 28.855 0 279 ASP B CB  1 ? 
ATOM   3769 C CG  . ASP B 1 244 ? -26.186 -38.503 2.578   1.000 28.300 0 279 ASP B CG  1 ? 
ATOM   3770 O OD1 . ASP B 1 244 ? -27.254 -38.144 3.121   1.000 28.454 0 279 ASP B OD1 1 ? 
ATOM   3771 O OD2 . ASP B 1 244 ? -25.159 -38.695 3.201   1.000 27.628 0 279 ASP B OD2 1 ? 
ATOM   3772 N N   . PRO B 1 245 ? -29.415 -37.284 1.140   1.000 26.171 0 280 PRO B N   1 ? 
ATOM   3773 C CA  . PRO B 1 245 ? -30.163 -36.058 1.410   1.000 27.448 0 280 PRO B CA  1 ? 
ATOM   3774 C C   . PRO B 1 245 ? -29.540 -35.098 2.429   1.000 24.725 0 280 PRO B C   1 ? 
ATOM   3775 O O   . PRO B 1 245 ? -29.887 -33.926 2.436   1.000 26.753 0 280 PRO B O   1 ? 
ATOM   3776 C CB  . PRO B 1 245 ? -31.508 -36.574 1.963   1.000 28.680 0 280 PRO B CB  1 ? 
ATOM   3777 C CG  . PRO B 1 245 ? -31.206 -37.955 2.479   1.000 29.904 0 280 PRO B CG  1 ? 
ATOM   3778 C CD  . PRO B 1 245 ? -30.181 -38.489 1.504   1.000 28.133 0 280 PRO B CD  1 ? 
ATOM   3779 N N   . ALA B 1 246 ? -28.602 -35.575 3.261   1.000 24.294 0 281 ALA B N   1 ? 
ATOM   3780 C CA  . ALA B 1 246 ? -27.864 -34.711 4.177   1.000 23.202 0 281 ALA B CA  1 ? 
ATOM   3781 C C   . ALA B 1 246 ? -26.894 -33.805 3.420   1.000 21.323 0 281 ALA B C   1 ? 
ATOM   3782 O O   . ALA B 1 246 ? -26.445 -32.812 3.965   1.000 22.572 0 281 ALA B O   1 ? 
ATOM   3783 C CB  . ALA B 1 246 ? -27.130 -35.543 5.210   1.000 22.918 0 281 ALA B CB  1 ? 
ATOM   3784 N N   . LEU B 1 247 ? -26.567 -34.165 2.170   1.000 21.667 0 282 LEU B N   1 ? 
ATOM   3785 C CA  . LEU B 1 247 ? -25.559 -33.461 1.391   1.000 21.503 0 282 LEU B CA  1 ? 
ATOM   3786 C C   . LEU B 1 247 ? -26.248 -32.646 0.307   1.000 22.470 0 282 LEU B C   1 ? 
ATOM   3787 O O   . LEU B 1 247 ? -27.206 -33.117 -0.314  1.000 21.119 0 282 LEU B O   1 ? 
ATOM   3788 C CB  . LEU B 1 247 ? -24.594 -34.456 0.735   1.000 21.933 0 282 LEU B CB  1 ? 
ATOM   3789 C CG  . LEU B 1 247 ? -23.836 -35.432 1.635   1.000 23.180 0 282 LEU B CG  1 ? 
ATOM   3790 C CD1 . LEU B 1 247 ? -22.818 -36.197 0.807   1.000 22.981 0 282 LEU B CD1 1 ? 
ATOM   3791 C CD2 . LEU B 1 247 ? -23.155 -34.752 2.821   1.000 23.590 0 282 LEU B CD2 1 ? 
ATOM   3792 N N   . CYS B 1 248 ? -25.724 -31.441 0.067   1.000 22.661 0 283 CYS B N   1 ? 
ATOM   3793 C CA  A CYS B 1 248 ? -26.263 -30.568 -0.964  0.500 23.196 0 283 CYS B CA  1 ? 
ATOM   3794 C CA  B CYS B 1 248 ? -26.258 -30.563 -0.963  0.500 24.599 0 283 CYS B CA  1 ? 
ATOM   3795 C C   . CYS B 1 248 ? -25.280 -30.432 -2.125  1.000 23.697 0 283 CYS B C   1 ? 
ATOM   3796 O O   . CYS B 1 248 ? -25.570 -29.746 -3.099  1.000 24.793 0 283 CYS B O   1 ? 
ATOM   3797 C CB  A CYS B 1 248 ? -26.647 -29.212 -0.377  0.500 23.896 0 283 CYS B CB  1 ? 
ATOM   3798 C CB  B CYS B 1 248 ? -26.566 -29.177 -0.410  0.500 26.519 0 283 CYS B CB  1 ? 
ATOM   3799 S SG  A CYS B 1 248 ? -28.322 -29.189 0.331   0.500 22.742 0 283 CYS B SG  1 ? 
ATOM   3800 S SG  B CYS B 1 248 ? -25.092 -28.162 -0.157  0.500 31.690 0 283 CYS B SG  1 ? 
ATOM   3801 N N   . ASP B 1 249 ? -24.105 -31.060 -1.993  1.000 21.856 0 284 ASP B N   1 ? 
ATOM   3802 C CA  . ASP B 1 249 ? -23.182 -31.211 -3.101  1.000 21.009 0 284 ASP B CA  1 ? 
ATOM   3803 C C   . ASP B 1 249 ? -22.300 -32.414 -2.786  1.000 21.201 0 284 ASP B C   1 ? 
ATOM   3804 O O   . ASP B 1 249 ? -22.060 -32.724 -1.625  1.000 20.448 0 284 ASP B O   1 ? 
ATOM   3805 C CB  . ASP B 1 249 ? -22.372 -29.942 -3.360  1.000 21.387 0 284 ASP B CB  1 ? 
ATOM   3806 C CG  . ASP B 1 249 ? -21.847 -29.815 -4.782  1.000 23.381 0 284 ASP B CG  1 ? 
ATOM   3807 O OD1 . ASP B 1 249 ? -22.003 -30.768 -5.584  1.000 24.223 0 284 ASP B OD1 1 ? 
ATOM   3808 O OD2 . ASP B 1 249 ? -21.263 -28.776 -5.072  1.000 22.453 0 284 ASP B OD2 1 ? 
ATOM   3809 N N   . PHE B 1 250 ? -21.888 -33.125 -3.832  1.000 20.896 0 285 PHE B N   1 ? 
ATOM   3810 C CA  . PHE B 1 250 ? -21.038 -34.293 -3.681  1.000 21.649 0 285 PHE B CA  1 ? 
ATOM   3811 C C   . PHE B 1 250 ? -20.263 -34.463 -4.978  1.000 22.290 0 285 PHE B C   1 ? 
ATOM   3812 O O   . PHE B 1 250 ? -20.863 -34.465 -6.042  1.000 22.750 0 285 PHE B O   1 ? 
ATOM   3813 C CB  . PHE B 1 250 ? -21.849 -35.549 -3.329  1.000 22.332 0 285 PHE B CB  1 ? 
ATOM   3814 C CG  . PHE B 1 250 ? -20.990 -36.786 -3.157  1.000 21.374 0 285 PHE B CG  1 ? 
ATOM   3815 C CD1 . PHE B 1 250 ? -20.612 -37.540 -4.261  1.000 21.826 0 285 PHE B CD1 1 ? 
ATOM   3816 C CD2 . PHE B 1 250 ? -20.486 -37.141 -1.915  1.000 20.116 0 285 PHE B CD2 1 ? 
ATOM   3817 C CE1 . PHE B 1 250 ? -19.764 -38.633 -4.128  1.000 21.876 0 285 PHE B CE1 1 ? 
ATOM   3818 C CE2 . PHE B 1 250 ? -19.636 -38.228 -1.777  1.000 20.791 0 285 PHE B CE2 1 ? 
ATOM   3819 C CZ  . PHE B 1 250 ? -19.296 -38.992 -2.885  1.000 21.729 0 285 PHE B CZ  1 ? 
ATOM   3820 N N   . LYS B 1 251 ? -18.932 -34.543 -4.882  1.000 22.668 0 286 LYS B N   1 ? 
ATOM   3821 C CA  . LYS B 1 251 ? -18.073 -34.887 -6.007  1.000 23.047 0 286 LYS B CA  1 ? 
ATOM   3822 C C   . LYS B 1 251 ? -17.062 -35.925 -5.520  1.000 22.523 0 286 LYS B C   1 ? 
ATOM   3823 O O   . LYS B 1 251 ? -16.710 -35.915 -4.341  1.000 21.471 0 286 LYS B O   1 ? 
ATOM   3824 C CB  . LYS B 1 251 ? -17.326 -33.668 -6.560  1.000 23.109 0 286 LYS B CB  1 ? 
ATOM   3825 C CG  . LYS B 1 251 ? -18.166 -32.452 -6.941  1.000 23.612 0 286 LYS B CG  1 ? 
ATOM   3826 C CD  . LYS B 1 251 ? -17.280 -31.230 -7.246  1.000 23.905 0 286 LYS B CD  1 ? 
ATOM   3827 C CE  . LYS B 1 251 ? -18.021 -29.918 -7.410  1.000 24.464 0 286 LYS B CE  1 ? 
ATOM   3828 N NZ  . LYS B 1 251 ? -18.904 -29.954 -8.594  1.000 25.625 0 286 LYS B NZ  1 ? 
ATOM   3829 N N   . SER B 1 252 ? -16.629 -36.826 -6.413  1.000 24.174 0 287 SER B N   1 ? 
ATOM   3830 C CA  . SER B 1 252 ? -15.556 -37.750 -6.094  1.000 27.364 0 287 SER B CA  1 ? 
ATOM   3831 C C   . SER B 1 252 ? -14.811 -38.134 -7.362  1.000 29.718 0 287 SER B C   1 ? 
ATOM   3832 O O   . SER B 1 252 ? -15.346 -37.993 -8.446  1.000 27.748 0 287 SER B O   1 ? 
ATOM   3833 C CB  . SER B 1 252 ? -16.022 -38.982 -5.367  1.000 27.931 0 287 SER B CB  1 ? 
ATOM   3834 O OG  . SER B 1 252 ? -16.612 -39.905 -6.260  1.000 35.226 0 287 SER B OG  1 ? 
ATOM   3835 N N   . ASN B 1 253 ? -13.582 -38.632 -7.168  1.000 35.524 0 288 ASN B N   1 ? 
ATOM   3836 C CA  . ASN B 1 253 ? -12.707 -39.160 -8.200  1.000 36.477 0 288 ASN B CA  1 ? 
ATOM   3837 C C   . ASN B 1 253 ? -11.819 -40.243 -7.574  1.000 37.351 0 288 ASN B C   1 ? 
ATOM   3838 O O   . ASN B 1 253 ? -11.403 -40.096 -6.421  1.000 30.451 0 288 ASN B O   1 ? 
ATOM   3839 C CB  . ASN B 1 253 ? -11.825 -38.052 -8.780  1.000 38.659 0 288 ASN B CB  1 ? 
ATOM   3840 C CG  . ASN B 1 253 ? -12.624 -37.014 -9.540  1.000 47.549 0 288 ASN B CG  1 ? 
ATOM   3841 O OD1 . ASN B 1 253 ? -12.947 -37.212 -10.712 1.000 54.951 0 288 ASN B OD1 1 ? 
ATOM   3842 N ND2 . ASN B 1 253 ? -12.943 -35.903 -8.892  1.000 48.340 0 288 ASN B ND2 1 ? 
ATOM   3843 N N   . ASN B 1 254 ? -11.568 -41.318 -8.350  1.000 39.147 0 289 ASN B N   1 ? 
ATOM   3844 C CA  . ASN B 1 254 ? -10.539 -42.329 -8.115  1.000 39.955 0 289 ASN B CA  1 ? 
ATOM   3845 C C   . ASN B 1 254 ? -10.891 -43.223 -6.929  1.000 42.497 0 289 ASN B C   1 ? 
ATOM   3846 O O   . ASN B 1 254 ? -9.978  -43.648 -6.225  1.000 45.913 0 289 ASN B O   1 ? 
ATOM   3847 C CB  . ASN B 1 254 ? -9.137  -41.723 -7.908  1.000 36.717 0 289 ASN B CB  1 ? 
ATOM   3848 C CG  . ASN B 1 254 ? -8.726  -40.774 -9.011  1.000 40.218 0 289 ASN B CG  1 ? 
ATOM   3849 O OD1 . ASN B 1 254 ? -8.715  -41.154 -10.176 1.000 37.757 0 289 ASN B OD1 1 ? 
ATOM   3850 N ND2 . ASN B 1 254 ? -8.457  -39.521 -8.673  1.000 40.420 0 289 ASN B ND2 1 ? 
ATOM   3851 N N   . LEU B 1 255 ? -12.182 -43.509 -6.689  1.000 48.107 0 290 LEU B N   1 ? 
ATOM   3852 C CA  . LEU B 1 255 ? -12.562 -44.345 -5.544  1.000 48.313 0 290 LEU B CA  1 ? 
ATOM   3853 C C   . LEU B 1 255 ? -12.678 -45.824 -5.922  1.000 50.842 0 290 LEU B C   1 ? 
ATOM   3854 O O   . LEU B 1 255 ? -12.845 -46.687 -5.050  1.000 43.829 0 290 LEU B O   1 ? 
ATOM   3855 C CB  . LEU B 1 255 ? -13.894 -43.857 -4.958  1.000 47.762 0 290 LEU B CB  1 ? 
ATOM   3856 C CG  . LEU B 1 255 ? -13.895 -42.476 -4.300  1.000 41.890 0 290 LEU B CG  1 ? 
ATOM   3857 C CD1 . LEU B 1 255 ? -15.128 -42.323 -3.418  1.000 42.939 0 290 LEU B CD1 1 ? 
ATOM   3858 C CD2 . LEU B 1 255 ? -12.632 -42.234 -3.506  1.000 40.310 0 290 LEU B CD2 1 ? 
ATOM   3859 N N   . PHE B 1 256 ? -12.635 -46.102 -7.233  1.000 55.753 0 291 PHE B N   1 ? 
ATOM   3860 C CA  . PHE B 1 256 ? -12.739 -47.455 -7.771  1.000 60.760 0 291 PHE B CA  1 ? 
ATOM   3861 C C   . PHE B 1 256 ? -14.065 -48.081 -7.333  1.000 55.401 0 291 PHE B C   1 ? 
ATOM   3862 O O   . PHE B 1 256 ? -14.117 -49.216 -6.867  1.000 46.362 0 291 PHE B O   1 ? 
ATOM   3863 C CB  . PHE B 1 256 ? -11.465 -48.247 -7.446  1.000 64.911 0 291 PHE B CB  1 ? 
ATOM   3864 C CG  . PHE B 1 256 ? -10.248 -47.727 -8.177  1.000 67.025 0 291 PHE B CG  1 ? 
ATOM   3865 C CD1 . PHE B 1 256 ? -10.074 -47.972 -9.534  1.000 71.054 0 291 PHE B CD1 1 ? 
ATOM   3866 C CD2 . PHE B 1 256 ? -9.325  -46.912 -7.531  1.000 69.221 0 291 PHE B CD2 1 ? 
ATOM   3867 C CE1 . PHE B 1 256 ? -8.975  -47.463 -10.211 1.000 76.181 0 291 PHE B CE1 1 ? 
ATOM   3868 C CE2 . PHE B 1 256 ? -8.228  -46.400 -8.208  1.000 71.921 0 291 PHE B CE2 1 ? 
ATOM   3869 C CZ  . PHE B 1 256 ? -8.054  -46.679 -9.546  1.000 77.709 0 291 PHE B CZ  1 ? 
ATOM   3870 N N   . CYS B 1 257 ? -15.121 -47.277 -7.529  1.000 58.140 0 292 CYS B N   1 ? 
ATOM   3871 C CA  . CYS B 1 257 ? -16.513 -47.694 -7.523  1.000 58.021 0 292 CYS B CA  1 ? 
ATOM   3872 C C   . CYS B 1 257 ? -16.821 -48.474 -8.815  1.000 55.562 0 292 CYS B C   1 ? 
ATOM   3873 O O   . CYS B 1 257 ? -17.763 -49.295 -8.788  1.000 53.207 0 292 CYS B O   1 ? 
ATOM   3874 C CB  . CYS B 1 257 ? -17.425 -46.468 -7.418  1.000 53.881 0 292 CYS B CB  1 ? 
ATOM   3875 S SG  . CYS B 1 257 ? -17.051 -45.355 -6.031  1.000 48.328 0 292 CYS B SG  1 ? 
HETATM 3876 C C1  . GOL C 2 .   ? -6.538  9.745   33.306  1.000 37.550 0 301 GOL A C1  1 ? 
HETATM 3877 O O1  . GOL C 2 .   ? -7.077  11.052  33.119  1.000 38.357 0 301 GOL A O1  1 ? 
HETATM 3878 C C2  . GOL C 2 .   ? -7.609  8.675   33.200  1.000 33.613 0 301 GOL A C2  1 ? 
HETATM 3879 O O2  . GOL C 2 .   ? -8.647  8.927   34.146  1.000 25.725 0 301 GOL A O2  1 ? 
HETATM 3880 C C3  . GOL C 2 .   ? -8.186  8.551   31.805  1.000 32.876 0 301 GOL A C3  1 ? 
HETATM 3881 O O3  . GOL C 2 .   ? -8.786  7.278   31.617  1.000 33.218 0 301 GOL A O3  1 ? 
HETATM 3882 C C1  . EDO D 3 .   ? 3.016   0.453   27.951  1.000 42.994 0 302 EDO A C1  1 ? 
HETATM 3883 O O1  . EDO D 3 .   ? 2.220   0.463   29.125  1.000 40.193 0 302 EDO A O1  1 ? 
HETATM 3884 C C2  . EDO D 3 .   ? 2.689   1.548   27.002  1.000 43.888 0 302 EDO A C2  1 ? 
HETATM 3885 O O2  . EDO D 3 .   ? 2.381   1.045   25.707  1.000 44.048 0 302 EDO A O2  1 ? 
HETATM 3886 S S   . SO4 E 4 .   ? -10.349 -18.204 10.584  1.000 89.861 0 301 SO4 B S   1 ? 
HETATM 3887 O O1  . SO4 E 4 .   ? -8.981  -17.955 10.940  1.000 87.377 0 301 SO4 B O1  1 ? 
HETATM 3888 O O2  . SO4 E 4 .   ? -11.202 -17.819 11.694  1.000 81.258 0 301 SO4 B O2  1 ? 
HETATM 3889 O O3  . SO4 E 4 .   ? -10.679 -17.427 9.414   1.000 75.467 0 301 SO4 B O3  1 ? 
HETATM 3890 O O4  . SO4 E 4 .   ? -10.512 -19.611 10.277  1.000 80.961 0 301 SO4 B O4  1 ? 
HETATM 3891 C C1  . EDO F 3 .   ? -12.892 -41.033 -12.864 1.000 61.284 0 302 EDO B C1  1 ? 
HETATM 3892 O O1  . EDO F 3 .   ? -12.326 -39.773 -12.551 1.000 58.937 0 302 EDO B O1  1 ? 
HETATM 3893 C C2  . EDO F 3 .   ? -12.729 -41.993 -11.756 1.000 61.675 0 302 EDO B C2  1 ? 
HETATM 3894 O O2  . EDO F 3 .   ? -12.968 -41.382 -10.501 1.000 61.045 0 302 EDO B O2  1 ? 
HETATM 3895 C C1  . EDO G 3 .   ? -7.999  -48.715 -0.743  1.000 60.127 0 303 EDO B C1  1 ? 
HETATM 3896 O O1  . EDO G 3 .   ? -6.785  -48.657 -0.013  1.000 56.179 0 303 EDO B O1  1 ? 
HETATM 3897 C C2  . EDO G 3 .   ? -8.831  -49.861 -0.336  1.000 60.067 0 303 EDO B C2  1 ? 
HETATM 3898 O O2  . EDO G 3 .   ? -8.184  -51.104 -0.536  1.000 62.718 0 303 EDO B O2  1 ? 
HETATM 3899 O O   . HOH H 5 .   ? -6.834  6.412   19.113  1.000 36.082 0 401 HOH A O   1 ? 
HETATM 3900 O O   . HOH H 5 .   ? -30.559 -25.552 34.595  1.000 34.615 0 402 HOH A O   1 ? 
HETATM 3901 O O   . HOH H 5 .   ? 0.720   -7.004  32.875  1.000 40.649 0 403 HOH A O   1 ? 
HETATM 3902 O O   . HOH H 5 .   ? -29.522 -15.543 17.095  1.000 36.540 0 404 HOH A O   1 ? 
HETATM 3903 O O   . HOH H 5 .   ? -31.110 -31.511 30.481  1.000 35.651 0 405 HOH A O   1 ? 
HETATM 3904 O O   . HOH H 5 .   ? -26.175 -16.942 13.331  1.000 40.382 0 406 HOH A O   1 ? 
HETATM 3905 O O   . HOH H 5 .   ? -25.432 -19.720 50.812  1.000 32.059 0 407 HOH A O   1 ? 
HETATM 3906 O O   . HOH H 5 .   ? -32.353 -27.139 25.161  1.000 25.820 0 408 HOH A O   1 ? 
HETATM 3907 O O   . HOH H 5 .   ? -3.388  -19.940 23.661  1.000 14.275 0 409 HOH A O   1 ? 
HETATM 3908 O O   . HOH H 5 .   ? -6.838  0.996   49.985  1.000 25.460 0 410 HOH A O   1 ? 
HETATM 3909 O O   . HOH H 5 .   ? -25.206 -5.320  45.555  1.000 27.035 0 411 HOH A O   1 ? 
HETATM 3910 O O   . HOH H 5 .   ? -1.864  -8.563  12.227  1.000 29.210 0 412 HOH A O   1 ? 
HETATM 3911 O O   . HOH H 5 .   ? -10.281 3.241   47.227  1.000 28.127 0 413 HOH A O   1 ? 
HETATM 3912 O O   . HOH H 5 .   ? -9.575  8.547   41.375  1.000 21.673 0 414 HOH A O   1 ? 
HETATM 3913 O O   . HOH H 5 .   ? -20.900 -5.585  9.449   1.000 35.751 0 415 HOH A O   1 ? 
HETATM 3914 O O   . HOH H 5 .   ? -20.785 4.848   31.784  1.000 38.451 0 416 HOH A O   1 ? 
HETATM 3915 O O   . HOH H 5 .   ? 0.002   -14.017 15.627  1.000 26.289 0 417 HOH A O   1 ? 
HETATM 3916 O O   . HOH H 5 .   ? -9.241  -20.829 44.118  1.000 36.192 0 418 HOH A O   1 ? 
HETATM 3917 O O   . HOH H 5 .   ? 3.921   -10.699 35.640  1.000 40.574 0 419 HOH A O   1 ? 
HETATM 3918 O O   . HOH H 5 .   ? -17.260 -16.071 53.264  1.000 35.215 0 420 HOH A O   1 ? 
HETATM 3919 O O   . HOH H 5 .   ? -15.152 -23.942 30.787  1.000 21.774 0 421 HOH A O   1 ? 
HETATM 3920 O O   . HOH H 5 .   ? -30.911 -14.363 23.384  1.000 25.309 0 422 HOH A O   1 ? 
HETATM 3921 O O   . HOH H 5 .   ? -17.547 -29.402 22.728  1.000 46.329 0 423 HOH A O   1 ? 
HETATM 3922 O O   . HOH H 5 .   ? -12.421 6.129   43.406  1.000 33.039 0 424 HOH A O   1 ? 
HETATM 3923 O O   . HOH H 5 .   ? -4.388  -13.874 44.934  1.000 23.968 0 425 HOH A O   1 ? 
HETATM 3924 O O   . HOH H 5 .   ? -8.073  11.514  35.636  1.000 23.972 0 426 HOH A O   1 ? 
HETATM 3925 O O   . HOH H 5 .   ? -1.272  4.982   22.102  1.000 32.860 0 427 HOH A O   1 ? 
HETATM 3926 O O   . HOH H 5 .   ? -37.862 -14.027 30.748  1.000 24.882 0 428 HOH A O   1 ? 
HETATM 3927 O O   . HOH H 5 .   ? -1.493  -15.862 26.588  1.000 23.392 0 429 HOH A O   1 ? 
HETATM 3928 O O   . HOH H 5 .   ? -26.312 -0.257  26.398  1.000 29.344 0 430 HOH A O   1 ? 
HETATM 3929 O O   . HOH H 5 .   ? -28.963 -8.993  28.080  1.000 25.165 0 431 HOH A O   1 ? 
HETATM 3930 O O   . HOH H 5 .   ? -13.640 -20.487 49.549  1.000 22.915 0 432 HOH A O   1 ? 
HETATM 3931 O O   . HOH H 5 .   ? -20.252 0.310   38.352  1.000 37.339 0 433 HOH A O   1 ? 
HETATM 3932 O O   . HOH H 5 .   ? -13.847 -26.817 44.868  1.000 39.162 0 434 HOH A O   1 ? 
HETATM 3933 O O   . HOH H 5 .   ? -2.148  -0.413  18.525  1.000 17.698 0 435 HOH A O   1 ? 
HETATM 3934 O O   . HOH H 5 .   ? -13.972 -16.738 16.735  1.000 15.362 0 436 HOH A O   1 ? 
HETATM 3935 O O   . HOH H 5 .   ? -13.197 -6.825  46.279  1.000 33.711 0 437 HOH A O   1 ? 
HETATM 3936 O O   . HOH H 5 .   ? -26.070 -3.829  19.563  1.000 40.100 0 438 HOH A O   1 ? 
HETATM 3937 O O   . HOH H 5 .   ? -27.064 -13.598 13.483  1.000 34.078 0 439 HOH A O   1 ? 
HETATM 3938 O O   . HOH H 5 .   ? 1.813   -13.488 41.517  1.000 36.983 0 440 HOH A O   1 ? 
HETATM 3939 O O   . HOH H 5 .   ? 2.563   -9.400  26.181  1.000 23.794 0 441 HOH A O   1 ? 
HETATM 3940 O O   . HOH H 5 .   ? -29.321 -17.420 21.027  1.000 24.942 0 442 HOH A O   1 ? 
HETATM 3941 O O   . HOH H 5 .   ? -17.643 8.591   32.570  1.000 28.553 0 443 HOH A O   1 ? 
HETATM 3942 O O   . HOH H 5 .   ? -7.424  7.769   24.673  1.000 33.595 0 444 HOH A O   1 ? 
HETATM 3943 O O   . HOH H 5 .   ? -6.862  -20.368 36.280  1.000 27.375 0 445 HOH A O   1 ? 
HETATM 3944 O O   . HOH H 5 .   ? -17.139 1.404   19.104  1.000 15.599 0 446 HOH A O   1 ? 
HETATM 3945 O O   . HOH H 5 .   ? -28.578 -12.477 15.969  1.000 40.515 0 447 HOH A O   1 ? 
HETATM 3946 O O   . HOH H 5 .   ? -5.005  4.879   32.633  1.000 22.078 0 448 HOH A O   1 ? 
HETATM 3947 O O   . HOH H 5 .   ? -3.333  -8.928  48.728  1.000 17.120 0 449 HOH A O   1 ? 
HETATM 3948 O O   . HOH H 5 .   ? -24.644 -31.274 34.925  1.000 26.499 0 450 HOH A O   1 ? 
HETATM 3949 O O   . HOH H 5 .   ? -8.528  -22.964 23.165  1.000 13.835 0 451 HOH A O   1 ? 
HETATM 3950 O O   . HOH H 5 .   ? -18.029 -29.504 32.309  1.000 45.251 0 452 HOH A O   1 ? 
HETATM 3951 O O   . HOH H 5 .   ? -7.569  -24.741 32.508  1.000 38.935 0 453 HOH A O   1 ? 
HETATM 3952 O O   . HOH H 5 .   ? -8.716  -10.038 44.482  1.000 33.987 0 454 HOH A O   1 ? 
HETATM 3953 O O   . HOH H 5 .   ? -21.001 7.106   27.810  1.000 28.231 0 455 HOH A O   1 ? 
HETATM 3954 O O   . HOH H 5 .   ? -28.917 -33.980 28.828  1.000 31.775 0 456 HOH A O   1 ? 
HETATM 3955 O O   . HOH H 5 .   ? -1.253  -2.341  35.529  1.000 37.515 0 457 HOH A O   1 ? 
HETATM 3956 O O   . HOH H 5 .   ? -16.021 -9.793  44.408  1.000 15.060 0 458 HOH A O   1 ? 
HETATM 3957 O O   . HOH H 5 .   ? -15.043 5.616   35.445  1.000 24.259 0 459 HOH A O   1 ? 
HETATM 3958 O O   . HOH H 5 .   ? -8.577  12.282  31.288  1.000 40.167 0 460 HOH A O   1 ? 
HETATM 3959 O O   . HOH H 5 .   ? -29.275 -14.427 42.708  1.000 29.228 0 461 HOH A O   1 ? 
HETATM 3960 O O   . HOH H 5 .   ? -27.801 -6.538  36.797  1.000 24.578 0 462 HOH A O   1 ? 
HETATM 3961 O O   . HOH H 5 .   ? -31.969 -17.963 29.026  1.000 23.157 0 463 HOH A O   1 ? 
HETATM 3962 O O   . HOH H 5 .   ? -27.224 2.040   23.387  1.000 38.253 0 464 HOH A O   1 ? 
HETATM 3963 O O   . HOH H 5 .   ? -30.410 -10.634 31.643  1.000 38.220 0 465 HOH A O   1 ? 
HETATM 3964 O O   . HOH H 5 .   ? -12.868 12.186  29.132  1.000 34.294 0 466 HOH A O   1 ? 
HETATM 3965 O O   . HOH H 5 .   ? 3.415   -4.717  44.734  1.000 33.207 0 467 HOH A O   1 ? 
HETATM 3966 O O   . HOH H 5 .   ? -30.266 -11.142 29.107  1.000 24.534 0 468 HOH A O   1 ? 
HETATM 3967 O O   . HOH H 5 .   ? -6.543  -8.467  18.782  1.000 12.170 0 469 HOH A O   1 ? 
HETATM 3968 O O   . HOH H 5 .   ? -23.054 0.453   32.722  1.000 31.131 0 470 HOH A O   1 ? 
HETATM 3969 O O   . HOH H 5 .   ? -25.462 1.481   30.474  1.000 27.110 0 471 HOH A O   1 ? 
HETATM 3970 O O   . HOH H 5 .   ? -13.581 -5.649  9.256   1.000 29.649 0 472 HOH A O   1 ? 
HETATM 3971 O O   . HOH H 5 .   ? -28.986 -25.906 23.950  1.000 20.402 0 473 HOH A O   1 ? 
HETATM 3972 O O   . HOH H 5 .   ? 1.717   0.345   35.642  1.000 40.694 0 474 HOH A O   1 ? 
HETATM 3973 O O   . HOH H 5 .   ? -18.990 15.036  28.966  1.000 18.967 0 475 HOH A O   1 ? 
HETATM 3974 O O   . HOH H 5 .   ? -3.494  -18.104 45.502  1.000 40.077 0 476 HOH A O   1 ? 
HETATM 3975 O O   . HOH H 5 .   ? -27.666 -19.014 17.124  1.000 31.911 0 477 HOH A O   1 ? 
HETATM 3976 O O   . HOH H 5 .   ? -20.376 0.203   35.583  1.000 17.438 0 478 HOH A O   1 ? 
HETATM 3977 O O   . HOH H 5 .   ? -6.933  2.442   43.428  1.000 17.724 0 479 HOH A O   1 ? 
HETATM 3978 O O   . HOH H 5 .   ? 6.706   -6.580  20.285  1.000 37.452 0 480 HOH A O   1 ? 
HETATM 3979 O O   . HOH H 5 .   ? -9.009  -7.105  17.578  1.000 14.796 0 481 HOH A O   1 ? 
HETATM 3980 O O   . HOH H 5 .   ? -29.112 -27.184 34.032  1.000 31.660 0 482 HOH A O   1 ? 
HETATM 3981 O O   . HOH H 5 .   ? -20.730 -0.681  10.423  1.000 41.723 0 483 HOH A O   1 ? 
HETATM 3982 O O   . HOH H 5 .   ? -6.163  -9.745  45.646  1.000 27.770 0 484 HOH A O   1 ? 
HETATM 3983 O O   . HOH H 5 .   ? -22.777 -28.614 28.824  1.000 30.569 0 485 HOH A O   1 ? 
HETATM 3984 O O   . HOH H 5 .   ? 0.386   -17.244 28.058  1.000 30.386 0 486 HOH A O   1 ? 
HETATM 3985 O O   . HOH H 5 .   ? -22.980 -10.228 13.585  1.000 26.561 0 487 HOH A O   1 ? 
HETATM 3986 O O   . HOH H 5 .   ? -20.999 -22.021 46.924  1.000 21.078 0 488 HOH A O   1 ? 
HETATM 3987 O O   . HOH H 5 .   ? -3.062  -6.933  15.663  1.000 17.614 0 489 HOH A O   1 ? 
HETATM 3988 O O   . HOH H 5 .   ? -6.351  -14.817 9.393   1.000 35.071 0 490 HOH A O   1 ? 
HETATM 3989 O O   . HOH H 5 .   ? -27.642 -5.771  18.347  1.000 35.329 0 491 HOH A O   1 ? 
HETATM 3990 O O   . HOH H 5 .   ? -11.777 -19.276 22.500  1.000 17.344 0 492 HOH A O   1 ? 
HETATM 3991 O O   . HOH H 5 .   ? -26.250 -3.046  43.057  1.000 37.124 0 493 HOH A O   1 ? 
HETATM 3992 O O   . HOH H 5 .   ? -31.768 -23.048 22.015  1.000 29.825 0 494 HOH A O   1 ? 
HETATM 3993 O O   . HOH H 5 .   ? -19.280 -24.140 21.680  1.000 15.691 0 495 HOH A O   1 ? 
HETATM 3994 O O   . HOH H 5 .   ? -0.468  0.994   36.584  1.000 32.518 0 496 HOH A O   1 ? 
HETATM 3995 O O   . HOH H 5 .   ? -20.659 5.213   19.879  1.000 37.272 0 497 HOH A O   1 ? 
HETATM 3996 O O   . HOH H 5 .   ? -27.165 -1.923  36.338  1.000 32.257 0 498 HOH A O   1 ? 
HETATM 3997 O O   . HOH H 5 .   ? -24.235 -6.201  11.011  1.000 41.110 0 499 HOH A O   1 ? 
HETATM 3998 O O   . HOH H 5 .   ? -2.497  -19.289 41.698  1.000 30.928 0 500 HOH A O   1 ? 
HETATM 3999 O O   . HOH H 5 .   ? -10.926 -7.416  46.689  1.000 38.444 0 501 HOH A O   1 ? 
HETATM 4000 O O   . HOH H 5 .   ? -31.296 -19.364 45.756  1.000 31.696 0 502 HOH A O   1 ? 
HETATM 4001 O O   . HOH H 5 .   ? -5.365  -22.751 28.895  1.000 40.881 0 503 HOH A O   1 ? 
HETATM 4002 O O   . HOH H 5 .   ? -25.437 -5.079  36.452  1.000 19.184 0 504 HOH A O   1 ? 
HETATM 4003 O O   . HOH H 5 .   ? -26.135 -21.386 10.463  1.000 27.441 0 505 HOH A O   1 ? 
HETATM 4004 O O   . HOH H 5 .   ? -30.409 -10.461 17.629  1.000 51.827 0 506 HOH A O   1 ? 
HETATM 4005 O O   . HOH H 5 .   ? -26.255 -1.355  41.035  1.000 47.989 0 507 HOH A O   1 ? 
HETATM 4006 O O   . HOH H 5 .   ? -11.476 -20.381 15.099  1.000 13.410 0 508 HOH A O   1 ? 
HETATM 4007 O O   . HOH H 5 .   ? -8.614  -22.974 29.792  1.000 22.017 0 509 HOH A O   1 ? 
HETATM 4008 O O   . HOH H 5 .   ? -14.712 7.062   25.886  1.000 37.387 0 510 HOH A O   1 ? 
HETATM 4009 O O   . HOH H 5 .   ? -21.853 -30.252 37.157  1.000 23.184 0 511 HOH A O   1 ? 
HETATM 4010 O O   . HOH H 5 .   ? -6.664  1.954   13.652  1.000 38.172 0 512 HOH A O   1 ? 
HETATM 4011 O O   . HOH H 5 .   ? -19.685 -11.407 13.055  1.000 28.142 0 513 HOH A O   1 ? 
HETATM 4012 O O   . HOH H 5 .   ? -19.207 -29.409 36.781  1.000 26.673 0 514 HOH A O   1 ? 
HETATM 4013 O O   . HOH H 5 .   ? 6.223   -1.920  26.428  1.000 36.177 0 515 HOH A O   1 ? 
HETATM 4014 O O   . HOH H 5 .   ? -17.622 -28.242 41.973  1.000 21.744 0 516 HOH A O   1 ? 
HETATM 4015 O O   . HOH H 5 .   ? -19.718 -16.483 54.279  1.000 32.599 0 517 HOH A O   1 ? 
HETATM 4016 O O   . HOH H 5 .   ? -10.459 10.613  29.956  1.000 21.323 0 518 HOH A O   1 ? 
HETATM 4017 O O   . HOH H 5 .   ? 4.236   -8.762  39.278  1.000 40.125 0 519 HOH A O   1 ? 
HETATM 4018 O O   . HOH H 5 .   ? -4.474  7.917   21.635  1.000 35.713 0 520 HOH A O   1 ? 
HETATM 4019 O O   . HOH H 5 .   ? -22.222 -28.517 41.056  1.000 32.324 0 521 HOH A O   1 ? 
HETATM 4020 O O   . HOH H 5 .   ? -10.513 -23.908 43.773  1.000 26.124 0 522 HOH A O   1 ? 
HETATM 4021 O O   . HOH H 5 .   ? -19.492 -14.258 10.615  1.000 29.548 0 523 HOH A O   1 ? 
HETATM 4022 O O   . HOH H 5 .   ? -18.442 0.154   11.098  1.000 21.728 0 524 HOH A O   1 ? 
HETATM 4023 O O   . HOH H 5 .   ? -17.724 7.588   16.152  1.000 31.514 0 525 HOH A O   1 ? 
HETATM 4024 O O   . HOH H 5 .   ? -1.618  4.002   18.638  1.000 31.716 0 526 HOH A O   1 ? 
HETATM 4025 O O   . HOH H 5 .   ? -4.000  -22.058 33.459  1.000 32.256 0 527 HOH A O   1 ? 
HETATM 4026 O O   . HOH H 5 .   ? -28.111 -8.449  32.153  1.000 47.367 0 528 HOH A O   1 ? 
HETATM 4027 O O   . HOH H 5 .   ? -2.829  -14.224 15.459  1.000 16.231 0 529 HOH A O   1 ? 
HETATM 4028 O O   . HOH H 5 .   ? -27.830 7.415   21.926  1.000 45.341 0 530 HOH A O   1 ? 
HETATM 4029 O O   . HOH H 5 .   ? -27.886 -17.230 18.663  1.000 31.803 0 531 HOH A O   1 ? 
HETATM 4030 O O   . HOH H 5 .   ? -19.974 10.456  22.171  1.000 35.059 0 532 HOH A O   1 ? 
HETATM 4031 O O   . HOH H 5 .   ? -2.127  5.019   32.022  1.000 24.733 0 533 HOH A O   1 ? 
HETATM 4032 O O   . HOH H 5 .   ? -25.418 1.743   27.773  1.000 19.153 0 534 HOH A O   1 ? 
HETATM 4033 O O   . HOH H 5 .   ? -3.005  5.540   17.671  1.000 37.015 0 535 HOH A O   1 ? 
HETATM 4034 O O   . HOH H 5 .   ? -0.062  -4.096  16.183  1.000 23.618 0 536 HOH A O   1 ? 
HETATM 4035 O O   . HOH H 5 .   ? -29.182 -11.573 43.443  1.000 25.681 0 537 HOH A O   1 ? 
HETATM 4036 O O   . HOH H 5 .   ? 0.004   -15.595 21.733  1.000 21.833 0 538 HOH A O   1 ? 
HETATM 4037 O O   . HOH H 5 .   ? 1.021   -3.869  43.746  1.000 21.474 0 539 HOH A O   1 ? 
HETATM 4038 O O   . HOH H 5 .   ? -16.674 2.183   40.064  1.000 35.970 0 540 HOH A O   1 ? 
HETATM 4039 O O   . HOH H 5 .   ? -27.955 -7.185  34.422  1.000 26.129 0 541 HOH A O   1 ? 
HETATM 4040 O O   . HOH H 5 .   ? -16.907 -11.950 13.893  1.000 38.020 0 542 HOH A O   1 ? 
HETATM 4041 O O   . HOH H 5 .   ? -3.589  7.117   33.677  1.000 27.890 0 543 HOH A O   1 ? 
HETATM 4042 O O   . HOH H 5 .   ? -18.623 -29.996 40.661  1.000 41.679 0 544 HOH A O   1 ? 
HETATM 4043 O O   . HOH H 5 .   ? -15.089 5.021   38.013  1.000 38.102 0 545 HOH A O   1 ? 
HETATM 4044 O O   . HOH H 5 .   ? -20.887 10.140  25.930  1.000 26.470 0 546 HOH A O   1 ? 
HETATM 4045 O O   . HOH H 5 .   ? -1.754  4.208   39.452  1.000 39.676 0 547 HOH A O   1 ? 
HETATM 4046 O O   . HOH H 5 .   ? -3.048  -4.095  13.320  1.000 19.970 0 548 HOH A O   1 ? 
HETATM 4047 O O   . HOH H 5 .   ? -32.492 -28.210 15.589  1.000 21.628 0 549 HOH A O   1 ? 
HETATM 4048 O O   . HOH H 5 .   ? -26.638 -26.629 19.102  1.000 31.861 0 550 HOH A O   1 ? 
HETATM 4049 O O   . HOH H 5 .   ? -27.554 -31.924 26.860  1.000 29.265 0 551 HOH A O   1 ? 
HETATM 4050 O O   . HOH H 5 .   ? -25.511 -17.704 56.341  1.000 45.074 0 552 HOH A O   1 ? 
HETATM 4051 O O   . HOH H 5 .   ? -9.475  -7.414  9.153   1.000 31.027 0 553 HOH A O   1 ? 
HETATM 4052 O O   . HOH H 5 .   ? -11.905 -10.619 8.957   1.000 49.568 0 554 HOH A O   1 ? 
HETATM 4053 O O   . HOH H 5 .   ? -21.788 -8.341  45.206  1.000 32.090 0 555 HOH A O   1 ? 
HETATM 4054 O O   . HOH H 5 .   ? -5.004  7.414   26.440  1.000 25.869 0 556 HOH A O   1 ? 
HETATM 4055 O O   . HOH H 5 .   ? -30.360 -9.010  23.473  1.000 27.357 0 557 HOH A O   1 ? 
HETATM 4056 O O   . HOH H 5 .   ? -15.792 -10.904 11.615  1.000 48.732 0 558 HOH A O   1 ? 
HETATM 4057 O O   . HOH H 5 .   ? -10.766 -10.841 45.988  1.000 28.374 0 559 HOH A O   1 ? 
HETATM 4058 O O   . HOH H 5 .   ? -30.658 -7.933  31.333  1.000 37.331 0 560 HOH A O   1 ? 
HETATM 4059 O O   . HOH H 5 .   ? -23.063 -27.526 22.962  1.000 40.451 0 561 HOH A O   1 ? 
HETATM 4060 O O   . HOH H 5 .   ? -24.235 -30.535 27.105  1.000 38.392 0 562 HOH A O   1 ? 
HETATM 4061 O O   . HOH H 5 .   ? -28.402 -24.816 16.800  1.000 25.056 0 563 HOH A O   1 ? 
HETATM 4062 O O   . HOH H 5 .   ? -20.219 -27.764 28.993  1.000 26.487 0 564 HOH A O   1 ? 
HETATM 4063 O O   . HOH H 5 .   ? 1.194   -11.191 30.032  1.000 40.950 0 565 HOH A O   1 ? 
HETATM 4064 O O   . HOH H 5 .   ? -3.596  -22.197 30.466  1.000 35.770 0 566 HOH A O   1 ? 
HETATM 4065 O O   . HOH H 5 .   ? -4.544  7.103   28.617  1.000 38.924 0 567 HOH A O   1 ? 
HETATM 4066 O O   . HOH H 5 .   ? 0.583   -4.209  35.203  1.000 43.226 0 568 HOH A O   1 ? 
HETATM 4067 O O   . HOH H 5 .   ? -32.188 -20.713 28.932  1.000 38.479 0 569 HOH A O   1 ? 
HETATM 4068 O O   . HOH H 5 .   ? -37.277 -15.586 28.885  1.000 42.797 0 570 HOH A O   1 ? 
HETATM 4069 O O   . HOH H 5 .   ? -29.537 -22.800 47.368  1.000 32.974 0 571 HOH A O   1 ? 
HETATM 4070 O O   . HOH H 5 .   ? -33.863 -21.979 29.218  1.000 45.489 0 572 HOH A O   1 ? 
HETATM 4071 O O   . HOH H 5 .   ? -0.511  4.960   30.526  1.000 40.243 0 573 HOH A O   1 ? 
HETATM 4072 O O   . HOH H 5 .   ? 6.305   -0.067  29.066  1.000 46.461 0 574 HOH A O   1 ? 
HETATM 4073 O O   . HOH H 5 .   ? -31.492 -6.437  33.680  1.000 41.943 0 575 HOH A O   1 ? 
HETATM 4074 O O   . HOH H 5 .   ? 1.805   -1.684  19.028  1.000 45.285 0 576 HOH A O   1 ? 
HETATM 4075 O O   . HOH H 5 .   ? -31.365 -8.265  37.962  1.000 39.050 0 577 HOH A O   1 ? 
HETATM 4076 O O   . HOH H 5 .   ? 8.777   -0.692  32.291  1.000 40.187 0 578 HOH A O   1 ? 
HETATM 4077 O O   . HOH H 5 .   ? -5.214  13.134  37.474  1.000 49.321 0 579 HOH A O   1 ? 
HETATM 4078 O O   . HOH H 5 .   ? 0.578   -9.926  12.603  1.000 36.603 0 580 HOH A O   1 ? 
HETATM 4079 O O   . HOH H 5 .   ? -15.732 -12.487 55.581  1.000 50.176 0 581 HOH A O   1 ? 
HETATM 4080 O O   . HOH H 5 .   ? -14.783 -26.487 30.273  1.000 31.554 0 582 HOH A O   1 ? 
HETATM 4081 O O   . HOH H 5 .   ? -10.446 7.555   21.140  1.000 37.923 0 583 HOH A O   1 ? 
HETATM 4082 O O   . HOH H 5 .   ? -11.748 -27.545 30.645  1.000 37.683 0 584 HOH A O   1 ? 
HETATM 4083 O O   . HOH H 5 .   ? -6.304  6.439   40.978  1.000 38.624 0 585 HOH A O   1 ? 
HETATM 4084 O O   . HOH H 5 .   ? -13.131 9.427   24.934  1.000 37.716 0 586 HOH A O   1 ? 
HETATM 4085 O O   . HOH H 5 .   ? -25.838 -15.910 6.996   1.000 47.242 0 587 HOH A O   1 ? 
HETATM 4086 O O   . HOH H 5 .   ? -20.216 5.596   16.790  1.000 47.228 0 588 HOH A O   1 ? 
HETATM 4087 O O   . HOH H 5 .   ? -20.495 -26.784 45.347  1.000 37.614 0 589 HOH A O   1 ? 
HETATM 4088 O O   . HOH H 5 .   ? -14.595 -28.229 40.208  1.000 45.815 0 590 HOH A O   1 ? 
HETATM 4089 O O   . HOH H 5 .   ? -17.938 12.869  32.061  1.000 42.603 0 591 HOH A O   1 ? 
HETATM 4090 O O   . HOH H 5 .   ? -2.000  -6.318  13.445  1.000 40.163 0 592 HOH A O   1 ? 
HETATM 4091 O O   . HOH H 5 .   ? 7.092   -6.627  17.833  1.000 50.436 0 593 HOH A O   1 ? 
HETATM 4092 O O   . HOH H 5 .   ? -3.712  -4.890  8.943   1.000 38.081 0 594 HOH A O   1 ? 
HETATM 4093 O O   . HOH H 5 .   ? -32.361 -14.164 25.843  1.000 41.664 0 595 HOH A O   1 ? 
HETATM 4094 O O   . HOH H 5 .   ? -4.866  -18.443 37.578  1.000 25.895 0 596 HOH A O   1 ? 
HETATM 4095 O O   . HOH H 5 .   ? -17.296 8.558   18.778  1.000 37.408 0 597 HOH A O   1 ? 
HETATM 4096 O O   . HOH H 5 .   ? -27.294 -24.638 11.828  1.000 37.240 0 598 HOH A O   1 ? 
HETATM 4097 O O   . HOH H 5 .   ? 3.324   -3.685  35.096  1.000 48.244 0 599 HOH A O   1 ? 
HETATM 4098 O O   . HOH H 5 .   ? -6.016  -3.962  4.427   1.000 39.314 0 600 HOH A O   1 ? 
HETATM 4099 O O   . HOH H 5 .   ? -32.264 -15.273 44.287  1.000 45.376 0 601 HOH A O   1 ? 
HETATM 4100 O O   . HOH H 5 .   ? -25.277 -28.879 12.844  1.000 30.789 0 602 HOH A O   1 ? 
HETATM 4101 O O   . HOH H 5 .   ? 6.689   -8.278  30.902  1.000 48.274 0 603 HOH A O   1 ? 
HETATM 4102 O O   . HOH H 5 .   ? -5.233  -10.657 47.956  1.000 25.604 0 604 HOH A O   1 ? 
HETATM 4103 O O   . HOH H 5 .   ? -22.120 4.800   18.015  1.000 51.739 0 605 HOH A O   1 ? 
HETATM 4104 O O   . HOH H 5 .   ? 0.188   0.590   45.450  1.000 35.391 0 606 HOH A O   1 ? 
HETATM 4105 O O   . HOH H 5 .   ? -21.541 7.386   30.308  1.000 36.095 0 607 HOH A O   1 ? 
HETATM 4106 O O   . HOH H 5 .   ? -0.108  0.167   41.321  1.000 40.456 0 608 HOH A O   1 ? 
HETATM 4107 O O   . HOH H 5 .   ? -20.346 -25.521 18.845  1.000 29.503 0 609 HOH A O   1 ? 
HETATM 4108 O O   . HOH H 5 .   ? -31.333 -6.656  39.653  1.000 39.810 0 610 HOH A O   1 ? 
HETATM 4109 O O   . HOH H 5 .   ? -31.465 -16.362 21.661  1.000 46.450 0 611 HOH A O   1 ? 
HETATM 4110 O O   . HOH H 5 .   ? -26.830 3.975   26.588  1.000 39.694 0 612 HOH A O   1 ? 
HETATM 4111 O O   . HOH H 5 .   ? -2.482  -0.005  15.882  1.000 29.908 0 613 HOH A O   1 ? 
HETATM 4112 O O   . HOH H 5 .   ? -12.062 -9.743  55.820  1.000 43.328 0 614 HOH A O   1 ? 
HETATM 4113 O O   . HOH H 5 .   ? -6.672  -23.606 34.796  1.000 40.204 0 615 HOH A O   1 ? 
HETATM 4114 O O   . HOH H 5 .   ? -27.380 2.693   34.091  1.000 42.752 0 616 HOH A O   1 ? 
HETATM 4115 O O   . HOH H 5 .   ? -2.877  -19.424 38.577  1.000 37.882 0 617 HOH A O   1 ? 
HETATM 4116 O O   . HOH H 5 .   ? -28.350 -17.524 14.566  1.000 49.911 0 618 HOH A O   1 ? 
HETATM 4117 O O   . HOH H 5 .   ? -1.473  -2.469  14.374  1.000 27.879 0 619 HOH A O   1 ? 
HETATM 4118 O O   . HOH H 5 .   ? -28.827 -2.141  19.918  1.000 45.121 0 620 HOH A O   1 ? 
HETATM 4119 O O   . HOH H 5 .   ? -17.420 6.932   35.116  1.000 37.525 0 621 HOH A O   1 ? 
HETATM 4120 O O   . HOH H 5 .   ? -8.579  -14.007 8.292   1.000 48.516 0 622 HOH A O   1 ? 
HETATM 4121 O O   . HOH H 5 .   ? -22.882 -32.465 35.383  1.000 36.609 0 623 HOH A O   1 ? 
HETATM 4122 O O   . HOH H 5 .   ? -18.167 -8.891  45.765  1.000 38.867 0 624 HOH A O   1 ? 
HETATM 4123 O O   . HOH H 5 .   ? -19.949 -26.675 21.369  1.000 37.161 0 625 HOH A O   1 ? 
HETATM 4124 O O   . HOH H 5 .   ? -11.530 -10.541 48.429  1.000 40.557 0 626 HOH A O   1 ? 
HETATM 4125 O O   . HOH H 5 .   ? -21.516 8.493   20.761  1.000 33.846 0 627 HOH A O   1 ? 
HETATM 4126 O O   . HOH H 5 .   ? -12.118 -12.771 51.249  1.000 47.176 0 628 HOH A O   1 ? 
HETATM 4127 O O   . HOH H 5 .   ? -20.812 -33.215 33.594  1.000 44.657 0 629 HOH A O   1 ? 
HETATM 4128 O O   . HOH H 5 .   ? -19.817 -6.996  45.210  1.000 28.727 0 630 HOH A O   1 ? 
HETATM 4129 O O   . HOH H 5 .   ? -23.176 -30.419 40.362  1.000 32.017 0 631 HOH A O   1 ? 
HETATM 4130 O O   . HOH H 5 .   ? -21.701 9.518   31.909  1.000 37.043 0 632 HOH A O   1 ? 
HETATM 4131 O O   . HOH H 5 .   ? 2.479   -13.886 24.678  1.000 49.274 0 633 HOH A O   1 ? 
HETATM 4132 O O   . HOH H 5 .   ? -19.688 -30.272 25.050  1.000 50.489 0 634 HOH A O   1 ? 
HETATM 4133 O O   . HOH H 5 .   ? -18.205 -29.031 29.950  1.000 38.102 0 635 HOH A O   1 ? 
HETATM 4134 O O   . HOH H 5 .   ? -23.054 -32.629 32.525  1.000 39.552 0 636 HOH A O   1 ? 
HETATM 4135 O O   . HOH H 5 .   ? -4.992  -14.579 49.289  1.000 41.429 0 637 HOH A O   1 ? 
HETATM 4136 O O   . HOH H 5 .   ? -0.250  -2.410  18.630  1.000 19.484 0 638 HOH A O   1 ? 
HETATM 4137 O O   . HOH H 5 .   ? -3.880  -12.999 47.535  1.000 33.159 0 639 HOH A O   1 ? 
HETATM 4138 O O   . HOH H 5 .   ? -30.256 -8.149  25.673  1.000 26.235 0 640 HOH A O   1 ? 
HETATM 4139 O O   . HOH H 5 .   ? -12.285 14.307  30.114  1.000 29.410 0 641 HOH A O   1 ? 
HETATM 4140 O O   . HOH H 5 .   ? 0.556   -1.429  40.224  1.000 48.869 0 642 HOH A O   1 ? 
HETATM 4141 O O   . HOH H 5 .   ? -15.524 -22.291 58.287  1.000 54.163 0 643 HOH A O   1 ? 
HETATM 4142 O O   . HOH H 5 .   ? -31.766 -12.988 48.816  1.000 37.694 0 644 HOH A O   1 ? 
HETATM 4143 O O   . HOH H 5 .   ? -8.450  -23.623 39.928  1.000 41.184 0 645 HOH A O   1 ? 
HETATM 4144 O O   . HOH H 5 .   ? -3.415  1.818   14.185  1.000 32.400 0 646 HOH A O   1 ? 
HETATM 4145 O O   . HOH H 5 .   ? -19.382 4.293   34.849  1.000 48.040 0 647 HOH A O   1 ? 
HETATM 4146 O O   . HOH H 5 .   ? -6.943  -13.248 51.442  1.000 38.089 0 648 HOH A O   1 ? 
HETATM 4147 O O   . HOH H 5 .   ? -3.899  -23.497 38.619  1.000 49.084 0 649 HOH A O   1 ? 
HETATM 4148 O O   . HOH I 5 .   ? -11.855 -18.431 13.605  1.000 36.544 0 401 HOH B O   1 ? 
HETATM 4149 O O   . HOH I 5 .   ? 5.340   -28.204 26.111  1.000 11.423 0 402 HOH B O   1 ? 
HETATM 4150 O O   . HOH I 5 .   ? 2.178   -19.232 13.099  1.000 28.103 0 403 HOH B O   1 ? 
HETATM 4151 O O   . HOH I 5 .   ? -21.481 -53.634 4.230   1.000 45.686 0 404 HOH B O   1 ? 
HETATM 4152 O O   . HOH I 5 .   ? -11.318 -15.497 -0.825  1.000 47.496 0 405 HOH B O   1 ? 
HETATM 4153 O O   . HOH I 5 .   ? -10.935 -34.082 23.472  1.000 16.927 0 406 HOH B O   1 ? 
HETATM 4154 O O   . HOH I 5 .   ? 3.268   -41.550 10.268  1.000 39.486 0 407 HOH B O   1 ? 
HETATM 4155 O O   . HOH I 5 .   ? -13.633 -58.617 10.484  1.000 50.431 0 408 HOH B O   1 ? 
HETATM 4156 O O   . HOH I 5 .   ? -22.008 -49.085 15.612  1.000 22.915 0 409 HOH B O   1 ? 
HETATM 4157 O O   . HOH I 5 .   ? -2.667  -37.641 -9.812  1.000 43.534 0 410 HOH B O   1 ? 
HETATM 4158 O O   . HOH I 5 .   ? 2.188   -44.999 4.495   1.000 33.507 0 411 HOH B O   1 ? 
HETATM 4159 O O   . HOH I 5 .   ? 6.030   -38.830 12.677  1.000 29.292 0 412 HOH B O   1 ? 
HETATM 4160 O O   . HOH I 5 .   ? 1.182   -27.028 -3.456  1.000 40.880 0 413 HOH B O   1 ? 
HETATM 4161 O O   . HOH I 5 .   ? -0.403  -54.750 20.878  1.000 33.317 0 414 HOH B O   1 ? 
HETATM 4162 O O   . HOH I 5 .   ? 2.456   -41.423 8.392   1.000 39.990 0 415 HOH B O   1 ? 
HETATM 4163 O O   . HOH I 5 .   ? -19.235 -47.384 28.720  1.000 33.450 0 416 HOH B O   1 ? 
HETATM 4164 O O   . HOH I 5 .   ? -15.209 -29.282 -9.327  1.000 50.643 0 417 HOH B O   1 ? 
HETATM 4165 O O   . HOH I 5 .   ? 0.537   -19.670 4.869   1.000 37.776 0 418 HOH B O   1 ? 
HETATM 4166 O O   . HOH I 5 .   ? -30.021 -26.572 1.874   1.000 34.416 0 419 HOH B O   1 ? 
HETATM 4167 O O   . HOH I 5 .   ? -10.493 -50.313 12.915  1.000 19.789 0 420 HOH B O   1 ? 
HETATM 4168 O O   . HOH I 5 .   ? -23.899 -20.435 8.939   1.000 18.311 0 421 HOH B O   1 ? 
HETATM 4169 O O   . HOH I 5 .   ? 2.925   -47.318 6.307   1.000 43.609 0 422 HOH B O   1 ? 
HETATM 4170 O O   . HOH I 5 .   ? -26.859 -52.095 11.853  1.000 36.650 0 423 HOH B O   1 ? 
HETATM 4171 O O   . HOH I 5 .   ? -0.949  -53.088 9.306   1.000 37.686 0 424 HOH B O   1 ? 
HETATM 4172 O O   . HOH I 5 .   ? 3.272   -20.124 10.775  1.000 38.783 0 425 HOH B O   1 ? 
HETATM 4173 O O   . HOH I 5 .   ? 0.976   -34.575 -8.102  1.000 25.849 0 426 HOH B O   1 ? 
HETATM 4174 O O   . HOH I 5 .   ? -23.833 -44.653 -1.400  1.000 35.277 0 427 HOH B O   1 ? 
HETATM 4175 O O   . HOH I 5 .   ? 4.647   -39.441 9.731   1.000 45.083 0 428 HOH B O   1 ? 
HETATM 4176 O O   . HOH I 5 .   ? -23.488 -30.812 13.496  1.000 18.759 0 429 HOH B O   1 ? 
HETATM 4177 O O   . HOH I 5 .   ? -31.415 -32.465 3.874   1.000 44.348 0 430 HOH B O   1 ? 
HETATM 4178 O O   . HOH I 5 .   ? -7.826  -25.187 26.891  1.000 25.263 0 431 HOH B O   1 ? 
HETATM 4179 O O   . HOH I 5 .   ? 3.489   -50.547 24.311  1.000 30.170 0 432 HOH B O   1 ? 
HETATM 4180 O O   . HOH I 5 .   ? -2.628  -37.256 32.273  1.000 31.323 0 433 HOH B O   1 ? 
HETATM 4181 O O   . HOH I 5 .   ? -26.878 -31.773 6.294   1.000 28.215 0 434 HOH B O   1 ? 
HETATM 4182 O O   . HOH I 5 .   ? -12.406 -52.888 9.945   1.000 32.551 0 435 HOH B O   1 ? 
HETATM 4183 O O   . HOH I 5 .   ? -20.570 -26.777 -3.579  1.000 22.453 0 436 HOH B O   1 ? 
HETATM 4184 O O   . HOH I 5 .   ? -17.754 -47.346 22.695  1.000 22.750 0 437 HOH B O   1 ? 
HETATM 4185 O O   . HOH I 5 .   ? 1.763   -36.370 0.184   1.000 42.640 0 438 HOH B O   1 ? 
HETATM 4186 O O   . HOH I 5 .   ? 5.755   -30.959 8.992   1.000 25.371 0 439 HOH B O   1 ? 
HETATM 4187 O O   . HOH I 5 .   ? -18.652 -54.736 21.513  1.000 39.971 0 440 HOH B O   1 ? 
HETATM 4188 O O   . HOH I 5 .   ? -15.155 -34.580 -9.422  1.000 41.351 0 441 HOH B O   1 ? 
HETATM 4189 O O   . HOH I 5 .   ? -27.001 -23.750 9.752   1.000 35.317 0 442 HOH B O   1 ? 
HETATM 4190 O O   . HOH I 5 .   ? -8.805  -34.218 29.415  1.000 33.968 0 443 HOH B O   1 ? 
HETATM 4191 O O   . HOH I 5 .   ? -19.191 -39.706 20.354  1.000 27.532 0 444 HOH B O   1 ? 
HETATM 4192 O O   . HOH I 5 .   ? -10.495 -21.886 13.088  1.000 17.398 0 445 HOH B O   1 ? 
HETATM 4193 O O   . HOH I 5 .   ? -3.058  -41.655 -4.215  1.000 39.939 0 446 HOH B O   1 ? 
HETATM 4194 O O   . HOH I 5 .   ? 6.357   -30.464 13.946  1.000 18.188 0 447 HOH B O   1 ? 
HETATM 4195 O O   . HOH I 5 .   ? -2.163  -38.452 -6.925  1.000 31.014 0 448 HOH B O   1 ? 
HETATM 4196 O O   . HOH I 5 .   ? -13.778 -52.945 23.782  1.000 18.683 0 449 HOH B O   1 ? 
HETATM 4197 O O   . HOH I 5 .   ? -25.686 -38.839 5.804   1.000 47.294 0 450 HOH B O   1 ? 
HETATM 4198 O O   . HOH I 5 .   ? -17.318 -50.178 12.461  1.000 29.551 0 451 HOH B O   1 ? 
HETATM 4199 O O   . HOH I 5 .   ? -13.857 -37.745 26.734  1.000 54.638 0 452 HOH B O   1 ? 
HETATM 4200 O O   . HOH I 5 .   ? -27.453 -28.183 8.742   1.000 63.401 0 453 HOH B O   1 ? 
HETATM 4201 O O   . HOH I 5 .   ? -13.018 -26.714 16.580  1.000 14.194 0 454 HOH B O   1 ? 
HETATM 4202 O O   . HOH I 5 .   ? -2.215  -30.579 -6.709  1.000 31.173 0 455 HOH B O   1 ? 
HETATM 4203 O O   . HOH I 5 .   ? 2.418   -44.754 9.134   1.000 35.889 0 456 HOH B O   1 ? 
HETATM 4204 O O   . HOH I 5 .   ? 4.956   -26.863 16.366  1.000 20.256 0 457 HOH B O   1 ? 
HETATM 4205 O O   . HOH I 5 .   ? -21.249 -31.249 -8.112  1.000 18.838 0 458 HOH B O   1 ? 
HETATM 4206 O O   . HOH I 5 .   ? 4.342   -35.647 9.555   1.000 21.156 0 459 HOH B O   1 ? 
HETATM 4207 O O   . HOH I 5 .   ? 3.503   -24.738 15.252  1.000 24.228 0 460 HOH B O   1 ? 
HETATM 4208 O O   . HOH I 5 .   ? -21.790 -27.098 16.900  1.000 24.720 0 461 HOH B O   1 ? 
HETATM 4209 O O   . HOH I 5 .   ? -8.201  -29.472 25.845  1.000 32.963 0 462 HOH B O   1 ? 
HETATM 4210 O O   . HOH I 5 .   ? 6.596   -34.989 19.044  1.000 32.982 0 463 HOH B O   1 ? 
HETATM 4211 O O   . HOH I 5 .   ? 8.364   -45.376 23.617  1.000 38.689 0 464 HOH B O   1 ? 
HETATM 4212 O O   . HOH I 5 .   ? 0.429   -22.642 3.120   1.000 30.267 0 465 HOH B O   1 ? 
HETATM 4213 O O   . HOH I 5 .   ? -16.727 -26.141 19.917  1.000 16.996 0 466 HOH B O   1 ? 
HETATM 4214 O O   . HOH I 5 .   ? 1.060   -15.926 10.073  1.000 50.103 0 467 HOH B O   1 ? 
HETATM 4215 O O   . HOH I 5 .   ? -2.047  -29.156 29.170  1.000 31.310 0 468 HOH B O   1 ? 
HETATM 4216 O O   . HOH I 5 .   ? 3.591   -32.682 32.721  1.000 38.812 0 469 HOH B O   1 ? 
HETATM 4217 O O   . HOH I 5 .   ? -18.273 -51.953 -0.053  1.000 26.363 0 470 HOH B O   1 ? 
HETATM 4218 O O   . HOH I 5 .   ? 4.577   -26.866 4.117   1.000 36.896 0 471 HOH B O   1 ? 
HETATM 4219 O O   . HOH I 5 .   ? 7.080   -39.707 26.846  1.000 23.889 0 472 HOH B O   1 ? 
HETATM 4220 O O   . HOH I 5 .   ? -10.745 -57.461 20.308  1.000 29.885 0 473 HOH B O   1 ? 
HETATM 4221 O O   . HOH I 5 .   ? -3.705  -33.251 -16.026 1.000 34.752 0 474 HOH B O   1 ? 
HETATM 4222 O O   . HOH I 5 .   ? -12.734 -25.501 22.613  1.000 12.759 0 475 HOH B O   1 ? 
HETATM 4223 O O   . HOH I 5 .   ? -1.152  -42.017 0.944   1.000 33.194 0 476 HOH B O   1 ? 
HETATM 4224 O O   . HOH I 5 .   ? -13.330 -46.816 29.378  1.000 26.513 0 477 HOH B O   1 ? 
HETATM 4225 O O   . HOH I 5 .   ? -9.287  -58.883 21.497  1.000 40.148 0 478 HOH B O   1 ? 
HETATM 4226 O O   . HOH I 5 .   ? 8.266   -42.068 13.864  1.000 41.191 0 479 HOH B O   1 ? 
HETATM 4227 O O   . HOH I 5 .   ? -20.363 -22.482 2.171   1.000 18.086 0 480 HOH B O   1 ? 
HETATM 4228 O O   . HOH I 5 .   ? 5.362   -36.458 12.218  1.000 24.422 0 481 HOH B O   1 ? 
HETATM 4229 O O   . HOH I 5 .   ? -5.701  -28.491 -3.577  1.000 15.867 0 482 HOH B O   1 ? 
HETATM 4230 O O   . HOH I 5 .   ? -3.906  -44.495 1.492   1.000 19.542 0 483 HOH B O   1 ? 
HETATM 4231 O O   . HOH I 5 .   ? -7.298  -53.128 26.528  1.000 33.233 0 484 HOH B O   1 ? 
HETATM 4232 O O   . HOH I 5 .   ? 4.261   -46.954 17.692  1.000 31.378 0 485 HOH B O   1 ? 
HETATM 4233 O O   . HOH I 5 .   ? -18.644 -41.646 -5.272  1.000 23.892 0 486 HOH B O   1 ? 
HETATM 4234 O O   . HOH I 5 .   ? 5.475   -23.685 14.001  1.000 45.353 0 487 HOH B O   1 ? 
HETATM 4235 O O   . HOH I 5 .   ? -17.179 -25.290 4.748   1.000 15.256 0 488 HOH B O   1 ? 
HETATM 4236 O O   . HOH I 5 .   ? 2.227   -15.533 16.862  1.000 33.192 0 489 HOH B O   1 ? 
HETATM 4237 O O   . HOH I 5 .   ? -5.292  -17.687 -2.656  1.000 38.315 0 490 HOH B O   1 ? 
HETATM 4238 O O   . HOH I 5 .   ? -26.530 -49.977 5.471   1.000 37.922 0 491 HOH B O   1 ? 
HETATM 4239 O O   . HOH I 5 .   ? -14.594 -24.543 3.549   1.000 16.267 0 492 HOH B O   1 ? 
HETATM 4240 O O   . HOH I 5 .   ? 2.961   -48.980 18.482  1.000 29.277 0 493 HOH B O   1 ? 
HETATM 4241 O O   . HOH I 5 .   ? -17.094 -32.806 21.650  1.000 31.220 0 494 HOH B O   1 ? 
HETATM 4242 O O   . HOH I 5 .   ? 4.309   -33.192 -8.209  1.000 23.273 0 495 HOH B O   1 ? 
HETATM 4243 O O   . HOH I 5 .   ? -6.006  -25.280 21.769  1.000 14.994 0 496 HOH B O   1 ? 
HETATM 4244 O O   . HOH I 5 .   ? -6.247  -50.737 25.673  1.000 18.344 0 497 HOH B O   1 ? 
HETATM 4245 O O   . HOH I 5 .   ? 0.450   -44.470 7.391   1.000 20.246 0 498 HOH B O   1 ? 
HETATM 4246 O O   . HOH I 5 .   ? -22.991 -38.852 -6.138  1.000 39.892 0 499 HOH B O   1 ? 
HETATM 4247 O O   . HOH I 5 .   ? -6.929  -21.658 20.864  1.000 18.645 0 500 HOH B O   1 ? 
HETATM 4248 O O   . HOH I 5 .   ? -15.414 -22.337 -6.321  1.000 38.271 0 501 HOH B O   1 ? 
HETATM 4249 O O   . HOH I 5 .   ? -3.534  -28.729 16.696  1.000 35.999 0 502 HOH B O   1 ? 
HETATM 4250 O O   . HOH I 5 .   ? 4.033   -24.769 5.479   1.000 32.067 0 503 HOH B O   1 ? 
HETATM 4251 O O   . HOH I 5 .   ? 6.177   -33.902 21.144  1.000 29.422 0 504 HOH B O   1 ? 
HETATM 4252 O O   . HOH I 5 .   ? -3.595  -20.307 7.334   1.000 19.086 0 505 HOH B O   1 ? 
HETATM 4253 O O   . HOH I 5 .   ? 1.153   -35.590 -5.190  1.000 40.549 0 506 HOH B O   1 ? 
HETATM 4254 O O   . HOH I 5 .   ? 1.213   -50.007 30.805  1.000 30.976 0 507 HOH B O   1 ? 
HETATM 4255 O O   . HOH I 5 .   ? -4.600  -56.397 15.768  1.000 33.663 0 508 HOH B O   1 ? 
HETATM 4256 O O   . HOH I 5 .   ? -18.038 -24.410 18.100  1.000 16.647 0 509 HOH B O   1 ? 
HETATM 4257 O O   . HOH I 5 .   ? -6.338  -16.008 -0.071  1.000 33.689 0 510 HOH B O   1 ? 
HETATM 4258 O O   . HOH I 5 .   ? 2.901   -50.116 15.811  1.000 32.366 0 511 HOH B O   1 ? 
HETATM 4259 O O   . HOH I 5 .   ? -21.163 -20.644 9.426   1.000 12.140 0 512 HOH B O   1 ? 
HETATM 4260 O O   . HOH I 5 .   ? -26.582 -39.869 13.669  1.000 38.982 0 513 HOH B O   1 ? 
HETATM 4261 O O   . HOH I 5 .   ? -19.222 -49.398 22.371  1.000 33.363 0 514 HOH B O   1 ? 
HETATM 4262 O O   . HOH I 5 .   ? -20.819 -27.475 -7.585  1.000 34.749 0 515 HOH B O   1 ? 
HETATM 4263 O O   . HOH I 5 .   ? -19.972 -31.980 20.856  1.000 39.851 0 516 HOH B O   1 ? 
HETATM 4264 O O   . HOH I 5 .   ? -12.986 -16.395 2.580   1.000 43.137 0 517 HOH B O   1 ? 
HETATM 4265 O O   . HOH I 5 .   ? -16.963 -41.926 -8.275  1.000 47.103 0 518 HOH B O   1 ? 
HETATM 4266 O O   . HOH I 5 .   ? -28.165 -39.059 5.692   1.000 36.849 0 519 HOH B O   1 ? 
HETATM 4267 O O   . HOH I 5 .   ? 3.921   -27.241 24.373  1.000 20.613 0 520 HOH B O   1 ? 
HETATM 4268 O O   . HOH I 5 .   ? -21.183 -41.281 -5.788  1.000 35.721 0 521 HOH B O   1 ? 
HETATM 4269 O O   . HOH I 5 .   ? -13.733 -15.412 7.189   1.000 41.226 0 522 HOH B O   1 ? 
HETATM 4270 O O   . HOH I 5 .   ? -17.564 -14.316 8.975   1.000 35.276 0 523 HOH B O   1 ? 
HETATM 4271 O O   . HOH I 5 .   ? -21.300 -41.304 18.553  1.000 28.696 0 524 HOH B O   1 ? 
HETATM 4272 O O   . HOH I 5 .   ? -23.290 -48.789 20.075  1.000 34.779 0 525 HOH B O   1 ? 
HETATM 4273 O O   . HOH I 5 .   ? -1.057  -37.581 -12.995 1.000 25.508 0 526 HOH B O   1 ? 
HETATM 4274 O O   . HOH I 5 .   ? -5.327  -38.835 31.741  1.000 25.475 0 527 HOH B O   1 ? 
HETATM 4275 O O   . HOH I 5 .   ? 1.655   -22.484 23.936  1.000 29.362 0 528 HOH B O   1 ? 
HETATM 4276 O O   . HOH I 5 .   ? -2.993  -44.663 28.959  1.000 37.360 0 529 HOH B O   1 ? 
HETATM 4277 O O   . HOH I 5 .   ? -25.492 -36.958 -2.384  1.000 31.840 0 530 HOH B O   1 ? 
HETATM 4278 O O   . HOH I 5 .   ? -12.858 -19.351 15.762  1.000 14.330 0 531 HOH B O   1 ? 
HETATM 4279 O O   . HOH I 5 .   ? -8.538  -45.436 -4.404  1.000 33.631 0 532 HOH B O   1 ? 
HETATM 4280 O O   . HOH I 5 .   ? 8.459   -30.941 18.664  1.000 35.934 0 533 HOH B O   1 ? 
HETATM 4281 O O   . HOH I 5 .   ? -22.213 -48.388 -3.446  1.000 40.102 0 534 HOH B O   1 ? 
HETATM 4282 O O   . HOH I 5 .   ? -14.602 -43.586 -8.347  1.000 55.929 0 535 HOH B O   1 ? 
HETATM 4283 O O   . HOH I 5 .   ? 3.255   -20.994 21.892  1.000 16.575 0 536 HOH B O   1 ? 
HETATM 4284 O O   . HOH I 5 .   ? -25.843 -42.716 -0.511  1.000 40.245 0 537 HOH B O   1 ? 
HETATM 4285 O O   . HOH I 5 .   ? 11.813  -31.698 23.539  1.000 47.877 0 538 HOH B O   1 ? 
HETATM 4286 O O   . HOH I 5 .   ? 6.356   -26.773 22.606  1.000 31.552 0 539 HOH B O   1 ? 
HETATM 4287 O O   . HOH I 5 .   ? -28.197 -23.223 3.981   1.000 40.024 0 540 HOH B O   1 ? 
HETATM 4288 O O   . HOH I 5 .   ? -26.746 -35.010 12.144  1.000 21.712 0 541 HOH B O   1 ? 
HETATM 4289 O O   . HOH I 5 .   ? -24.870 -26.211 11.693  1.000 23.283 0 542 HOH B O   1 ? 
HETATM 4290 O O   . HOH I 5 .   ? -5.588  -31.825 26.803  1.000 26.686 0 543 HOH B O   1 ? 
HETATM 4291 O O   . HOH I 5 .   ? -3.670  -20.664 -4.085  1.000 32.816 0 544 HOH B O   1 ? 
HETATM 4292 O O   . HOH I 5 .   ? 3.688   -19.549 7.445   1.000 44.469 0 545 HOH B O   1 ? 
HETATM 4293 O O   . HOH I 5 .   ? -24.258 -45.312 20.143  1.000 41.335 0 546 HOH B O   1 ? 
HETATM 4294 O O   . HOH I 5 .   ? -2.458  -17.910 6.309   1.000 38.844 0 547 HOH B O   1 ? 
HETATM 4295 O O   . HOH I 5 .   ? 0.098   -16.853 1.018   1.000 16.528 0 548 HOH B O   1 ? 
HETATM 4296 O O   . HOH I 5 .   ? -9.944  -43.804 30.517  1.000 36.124 0 549 HOH B O   1 ? 
HETATM 4297 O O   . HOH I 5 .   ? -15.183 -51.668 13.589  1.000 37.479 0 550 HOH B O   1 ? 
HETATM 4298 O O   . HOH I 5 .   ? -24.662 -18.294 5.306   1.000 30.609 0 551 HOH B O   1 ? 
HETATM 4299 O O   . HOH I 5 .   ? -28.533 -29.417 -3.628  1.000 46.387 0 552 HOH B O   1 ? 
HETATM 4300 O O   . HOH I 5 .   ? -25.932 -35.186 9.152   1.000 24.294 0 553 HOH B O   1 ? 
HETATM 4301 O O   . HOH I 5 .   ? 1.790   -37.002 29.274  1.000 40.013 0 554 HOH B O   1 ? 
HETATM 4302 O O   . HOH I 5 .   ? -22.243 -33.440 20.368  1.000 33.428 0 555 HOH B O   1 ? 
HETATM 4303 O O   . HOH I 5 .   ? -14.576 -41.730 -7.943  1.000 42.277 0 556 HOH B O   1 ? 
HETATM 4304 O O   . HOH I 5 .   ? -7.975  -52.522 28.600  1.000 36.407 0 557 HOH B O   1 ? 
HETATM 4305 O O   . HOH I 5 .   ? -19.837 -43.637 -7.560  1.000 38.892 0 558 HOH B O   1 ? 
HETATM 4306 O O   . HOH I 5 .   ? 3.823   -20.204 14.747  1.000 32.535 0 559 HOH B O   1 ? 
HETATM 4307 O O   . HOH I 5 .   ? -24.935 -26.783 -2.709  1.000 36.636 0 560 HOH B O   1 ? 
HETATM 4308 O O   . HOH I 5 .   ? -25.629 -29.666 -6.161  1.000 46.795 0 561 HOH B O   1 ? 
HETATM 4309 O O   . HOH I 5 .   ? -18.237 -28.322 20.864  1.000 44.132 0 562 HOH B O   1 ? 
HETATM 4310 O O   . HOH I 5 .   ? 0.405   -28.424 30.890  1.000 29.069 0 563 HOH B O   1 ? 
HETATM 4311 O O   . HOH I 5 .   ? -1.346  -55.442 25.248  1.000 39.116 0 564 HOH B O   1 ? 
HETATM 4312 O O   . HOH I 5 .   ? 7.507   -34.220 22.932  1.000 30.506 0 565 HOH B O   1 ? 
HETATM 4313 O O   . HOH I 5 .   ? -2.436  -54.346 26.831  1.000 50.367 0 566 HOH B O   1 ? 
HETATM 4314 O O   . HOH I 5 .   ? 10.678  -42.424 14.788  1.000 52.234 0 567 HOH B O   1 ? 
HETATM 4315 O O   . HOH I 5 .   ? 7.617   -26.322 19.819  1.000 35.787 0 568 HOH B O   1 ? 
HETATM 4316 O O   . HOH I 5 .   ? 3.821   -28.762 -5.688  1.000 38.652 0 569 HOH B O   1 ? 
HETATM 4317 O O   . HOH I 5 .   ? -18.466 -36.489 -8.993  1.000 37.825 0 570 HOH B O   1 ? 
HETATM 4318 O O   . HOH I 5 .   ? -18.506 -51.750 23.773  1.000 42.417 0 571 HOH B O   1 ? 
HETATM 4319 O O   . HOH I 5 .   ? 4.711   -26.366 27.421  1.000 24.734 0 572 HOH B O   1 ? 
HETATM 4320 O O   . HOH I 5 .   ? -15.402 -56.122 16.598  1.000 43.349 0 573 HOH B O   1 ? 
HETATM 4321 O O   . HOH I 5 .   ? 5.924   -45.810 11.502  1.000 48.796 0 574 HOH B O   1 ? 
HETATM 4322 O O   . HOH I 5 .   ? -25.595 -32.247 8.331   1.000 35.314 0 575 HOH B O   1 ? 
HETATM 4323 O O   . HOH I 5 .   ? 7.921   -35.032 5.921   1.000 44.334 0 576 HOH B O   1 ? 
HETATM 4324 O O   . HOH I 5 .   ? -0.094  -23.948 1.379   1.000 45.256 0 577 HOH B O   1 ? 
HETATM 4325 O O   . HOH I 5 .   ? 4.205   -20.412 4.951   1.000 45.142 0 578 HOH B O   1 ? 
HETATM 4326 O O   . HOH I 5 .   ? -9.081  -57.297 27.231  1.000 47.705 0 579 HOH B O   1 ? 
HETATM 4327 O O   . HOH I 5 .   ? 1.490   -20.693 26.679  1.000 39.559 0 580 HOH B O   1 ? 
HETATM 4328 O O   . HOH I 5 .   ? -18.297 -14.996 3.696   1.000 46.466 0 581 HOH B O   1 ? 
HETATM 4329 O O   . HOH I 5 .   ? -16.813 -55.595 0.649   1.000 46.231 0 582 HOH B O   1 ? 
HETATM 4330 O O   . HOH I 5 .   ? 6.657   -39.462 9.210   1.000 49.266 0 583 HOH B O   1 ? 
HETATM 4331 O O   . HOH I 5 .   ? -19.263 -38.657 -8.225  1.000 41.007 0 584 HOH B O   1 ? 
HETATM 4332 O O   . HOH I 5 .   ? -31.225 -29.192 7.493   1.000 42.070 0 585 HOH B O   1 ? 
HETATM 4333 O O   . HOH I 5 .   ? -24.832 -27.056 -5.267  1.000 47.024 0 586 HOH B O   1 ? 
HETATM 4334 O O   . HOH I 5 .   ? 7.490   -32.814 14.476  1.000 25.279 0 587 HOH B O   1 ? 
HETATM 4335 O O   . HOH I 5 .   ? -22.898 -53.915 12.850  1.000 44.552 0 588 HOH B O   1 ? 
HETATM 4336 O O   . HOH I 5 .   ? 4.408   -43.557 0.785   1.000 50.133 0 589 HOH B O   1 ? 
HETATM 4337 O O   . HOH I 5 .   ? 6.807   -30.300 11.254  1.000 31.846 0 590 HOH B O   1 ? 
HETATM 4338 O O   . HOH I 5 .   ? -11.424 -32.895 25.752  1.000 32.494 0 591 HOH B O   1 ? 
HETATM 4339 O O   . HOH I 5 .   ? 3.775   -51.550 22.152  1.000 39.155 0 592 HOH B O   1 ? 
HETATM 4340 O O   . HOH I 5 .   ? -20.437 -51.308 15.611  1.000 43.325 0 593 HOH B O   1 ? 
HETATM 4341 O O   . HOH I 5 .   ? 3.028   -16.375 21.117  1.000 44.166 0 594 HOH B O   1 ? 
HETATM 4342 O O   . HOH I 5 .   ? -4.703  -22.314 22.319  1.000 17.575 0 595 HOH B O   1 ? 
HETATM 4343 O O   . HOH I 5 .   ? -2.841  -58.667 17.660  1.000 46.560 0 596 HOH B O   1 ? 
HETATM 4344 O O   . HOH I 5 .   ? -1.855  -41.295 -6.443  1.000 42.908 0 597 HOH B O   1 ? 
HETATM 4345 O O   . HOH I 5 .   ? -10.007 -31.069 26.727  1.000 38.771 0 598 HOH B O   1 ? 
HETATM 4346 O O   . HOH I 5 .   ? -21.407 -32.548 -9.766  1.000 38.238 0 599 HOH B O   1 ? 
HETATM 4347 O O   . HOH I 5 .   ? -6.324  -26.863 27.294  1.000 40.493 0 600 HOH B O   1 ? 
HETATM 4348 O O   . HOH I 5 .   ? -18.146 -49.717 -4.964  1.000 55.261 0 601 HOH B O   1 ? 
HETATM 4349 O O   . HOH I 5 .   ? -15.651 -25.385 -12.372 1.000 45.352 0 602 HOH B O   1 ? 
HETATM 4350 O O   . HOH I 5 .   ? -25.442 -56.111 8.110   1.000 53.022 0 603 HOH B O   1 ? 
HETATM 4351 O O   . HOH I 5 .   ? -23.135 -23.518 -1.453  1.000 36.168 0 604 HOH B O   1 ? 
HETATM 4352 O O   . HOH I 5 .   ? 0.389   -15.502 24.285  1.000 34.142 0 605 HOH B O   1 ? 
HETATM 4353 O O   . HOH I 5 .   ? 7.916   -34.864 12.697  1.000 34.675 0 606 HOH B O   1 ? 
HETATM 4354 O O   . HOH I 5 .   ? 1.981   -53.320 14.474  1.000 42.510 0 607 HOH B O   1 ? 
HETATM 4355 O O   . HOH I 5 .   ? -29.913 -45.911 12.139  1.000 43.863 0 608 HOH B O   1 ? 
HETATM 4356 O O   . HOH I 5 .   ? -19.517 -24.064 -4.555  1.000 41.241 0 609 HOH B O   1 ? 
HETATM 4357 O O   . HOH I 5 .   ? 8.110   -29.785 5.041   1.000 45.877 0 610 HOH B O   1 ? 
HETATM 4358 O O   . HOH I 5 .   ? 7.643   -25.326 21.833  1.000 39.948 0 611 HOH B O   1 ? 
HETATM 4359 O O   . HOH I 5 .   ? 6.080   -48.342 11.030  1.000 44.158 0 612 HOH B O   1 ? 
HETATM 4360 O O   . HOH I 5 .   ? -11.980 -58.246 28.472  1.000 33.614 0 613 HOH B O   1 ? 
HETATM 4361 O O   . HOH I 5 .   ? -25.265 -47.686 1.591   1.000 46.680 0 614 HOH B O   1 ? 
HETATM 4362 O O   . HOH I 5 .   ? 6.662   -25.081 17.930  1.000 30.439 0 615 HOH B O   1 ? 
HETATM 4363 O O   . HOH I 5 .   ? -5.630  -24.179 24.001  1.000 33.587 0 616 HOH B O   1 ? 
HETATM 4364 O O   . HOH I 5 .   ? -18.123 -22.334 -6.041  1.000 38.667 0 617 HOH B O   1 ? 
HETATM 4365 O O   . HOH I 5 .   ? -29.502 -32.670 6.881   1.000 49.674 0 618 HOH B O   1 ? 
HETATM 4366 O O   . HOH I 5 .   ? -27.431 -32.637 12.932  1.000 42.867 0 619 HOH B O   1 ? 
HETATM 4367 O O   . HOH I 5 .   ? 11.935  -27.220 21.656  1.000 37.242 0 620 HOH B O   1 ? 
HETATM 4368 O O   . HOH I 5 .   ? 1.950   -25.249 25.050  1.000 24.194 0 621 HOH B O   1 ? 
HETATM 4369 O O   . HOH I 5 .   ? 5.748   -33.818 8.391   1.000 34.918 0 622 HOH B O   1 ? 
HETATM 4370 O O   . HOH I 5 .   ? -1.950  -44.031 0.255   1.000 39.897 0 623 HOH B O   1 ? 
HETATM 4371 O O   . HOH I 5 .   ? 1.363   -33.337 34.569  1.000 36.442 0 624 HOH B O   1 ? 
HETATM 4372 O O   . HOH I 5 .   ? -10.907 -47.085 30.612  1.000 36.534 0 625 HOH B O   1 ? 
HETATM 4373 O O   . HOH I 5 .   ? -22.700 -26.097 -1.689  1.000 24.409 0 626 HOH B O   1 ? 
HETATM 4374 O O   . HOH I 5 .   ? -29.571 -49.712 13.684  1.000 42.985 0 627 HOH B O   1 ? 
HETATM 4375 O O   . HOH I 5 .   ? -28.367 -36.293 8.592   1.000 43.790 0 628 HOH B O   1 ? 
HETATM 4376 O O   . HOH I 5 .   ? -11.383 -35.339 28.426  1.000 44.476 0 629 HOH B O   1 ? 
HETATM 4377 O O   . HOH I 5 .   ? -8.503  -48.334 30.833  1.000 39.231 0 630 HOH B O   1 ? 
HETATM 4378 O O   . HOH I 5 .   ? -4.303  -44.809 -1.539  1.000 39.784 0 631 HOH B O   1 ? 
HETATM 4379 O O   . HOH I 5 .   ? -14.873 -56.788 18.747  1.000 47.763 0 632 HOH B O   1 ? 
# 
