data_9JQK
# 
_entry.id   9JQK 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JQK         pdb_00009jqk 10.2210/pdb9jqk/pdb 
WWPDB D_1300051971 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-23 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JQK 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              xuwei3322@smu.edu.cn 
_pdbx_contact_author.name_first         Wei 
_pdbx_contact_author.name_last          Xu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3135-5010 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wu, F.' 1 ?                   
'Xu, W.' 2 0000-0002-3135-5010 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   NE 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Antiviral Res.' 
_citation.journal_id_ASTM           ARSRDR 
_citation.journal_id_CSD            1136 
_citation.journal_id_ISSN           0166-3542 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            234 
_citation.language                  ? 
_citation.page_first                106074 
_citation.page_last                 106074 
_citation.title                     
;Ginkgolic acid inhibits Ebola virus transcription and replication by disrupting the interaction between nucleoprotein and VP30 protein.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.antiviral.2024.106074 
_citation.pdbx_database_id_PubMed   39716669 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Peng, C.'  1 ? 
primary 'Wu, F.'    2 ? 
primary 'Ma, Y.'    3 ? 
primary 'Liu, G.'   4 ? 
primary 'Huang, Y.' 5 ? 
primary 'Tong, R.'  6 ? 
primary 'Xu, W.'    7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Transcriptional activator VP30'                      18296.742 4   ? ? ? ? 
2 non-polymer syn '2-[(~{E})-heptadec-10-enyl]-6-oxidanyl-benzoic acid' 374.557   2   ? ? ? ? 
3 non-polymer syn 'CHLORIDE ION'                                        35.453    3   ? ? ? ? 
4 water       nat water                                                 18.015    149 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'EbolaVP30,eVP30,Minor nucleoprotein VP30' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SVEQQLNITAPKDSRLANPTADDFQQEEGPKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLC
ETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVPQSDN
EE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SVEQQLNITAPKDSRLANPTADDFQQEEGPKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLC
ETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVPQSDN
EE
;
_entity_poly.pdbx_strand_id                 D,A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '2-[(~{E})-heptadec-10-enyl]-6-oxidanyl-benzoic acid' A1ECX 
3 'CHLORIDE ION'                                        CL    
4 water                                                 HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   VAL n 
1 3   GLU n 
1 4   GLN n 
1 5   GLN n 
1 6   LEU n 
1 7   ASN n 
1 8   ILE n 
1 9   THR n 
1 10  ALA n 
1 11  PRO n 
1 12  LYS n 
1 13  ASP n 
1 14  SER n 
1 15  ARG n 
1 16  LEU n 
1 17  ALA n 
1 18  ASN n 
1 19  PRO n 
1 20  THR n 
1 21  ALA n 
1 22  ASP n 
1 23  ASP n 
1 24  PHE n 
1 25  GLN n 
1 26  GLN n 
1 27  GLU n 
1 28  GLU n 
1 29  GLY n 
1 30  PRO n 
1 31  LYS n 
1 32  ILE n 
1 33  THR n 
1 34  LEU n 
1 35  LEU n 
1 36  THR n 
1 37  LEU n 
1 38  ILE n 
1 39  LYS n 
1 40  THR n 
1 41  ALA n 
1 42  GLU n 
1 43  HIS n 
1 44  TRP n 
1 45  ALA n 
1 46  ARG n 
1 47  GLN n 
1 48  ASP n 
1 49  ILE n 
1 50  ARG n 
1 51  THR n 
1 52  ILE n 
1 53  GLU n 
1 54  ASP n 
1 55  SER n 
1 56  LYS n 
1 57  LEU n 
1 58  ARG n 
1 59  ALA n 
1 60  LEU n 
1 61  LEU n 
1 62  THR n 
1 63  LEU n 
1 64  CYS n 
1 65  ALA n 
1 66  VAL n 
1 67  MET n 
1 68  THR n 
1 69  ARG n 
1 70  LYS n 
1 71  PHE n 
1 72  SER n 
1 73  LYS n 
1 74  SER n 
1 75  GLN n 
1 76  LEU n 
1 77  SER n 
1 78  LEU n 
1 79  LEU n 
1 80  CYS n 
1 81  GLU n 
1 82  THR n 
1 83  HIS n 
1 84  LEU n 
1 85  ARG n 
1 86  ARG n 
1 87  GLU n 
1 88  GLY n 
1 89  LEU n 
1 90  GLY n 
1 91  GLN n 
1 92  ASP n 
1 93  GLN n 
1 94  ALA n 
1 95  GLU n 
1 96  PRO n 
1 97  VAL n 
1 98  LEU n 
1 99  GLU n 
1 100 VAL n 
1 101 TYR n 
1 102 GLN n 
1 103 ARG n 
1 104 LEU n 
1 105 HIS n 
1 106 SER n 
1 107 ASP n 
1 108 LYS n 
1 109 GLY n 
1 110 GLY n 
1 111 SER n 
1 112 PHE n 
1 113 GLU n 
1 114 ALA n 
1 115 ALA n 
1 116 LEU n 
1 117 TRP n 
1 118 GLN n 
1 119 GLN n 
1 120 TRP n 
1 121 ASP n 
1 122 ARG n 
1 123 GLN n 
1 124 SER n 
1 125 LEU n 
1 126 ILE n 
1 127 MET n 
1 128 PHE n 
1 129 ILE n 
1 130 THR n 
1 131 ALA n 
1 132 PHE n 
1 133 LEU n 
1 134 ASN n 
1 135 ILE n 
1 136 ALA n 
1 137 LEU n 
1 138 GLN n 
1 139 LEU n 
1 140 PRO n 
1 141 CYS n 
1 142 GLU n 
1 143 SER n 
1 144 SER n 
1 145 ALA n 
1 146 VAL n 
1 147 VAL n 
1 148 VAL n 
1 149 SER n 
1 150 GLY n 
1 151 LEU n 
1 152 ARG n 
1 153 THR n 
1 154 LEU n 
1 155 VAL n 
1 156 PRO n 
1 157 GLN n 
1 158 SER n 
1 159 ASP n 
1 160 ASN n 
1 161 GLU n 
1 162 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   162 
_entity_src_gen.gene_src_common_name               'ZEBOV, Zaire Ebola virus' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 VP30 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    Kikwit-95 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Ebola virus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     128951 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1ECX non-polymer         . '2-[(~{E})-heptadec-10-enyl]-6-oxidanyl-benzoic acid' ? 'C24 H38 O3'     374.557 
ALA   'L-peptide linking' y ALANINE                                               ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                              ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                            ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                       ? 'C4 H7 N O4'     133.103 
CL    non-polymer         . 'CHLORIDE ION'                                        ? 'Cl -1'          35.453  
CYS   'L-peptide linking' y CYSTEINE                                              ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                             ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                       ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                               ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                             ? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                                                 ? 'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                            ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                               ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                            ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                         ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                               ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                             ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                            ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                              ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   111 ?   ?   ?   D . n 
A 1 2   VAL 2   112 ?   ?   ?   D . n 
A 1 3   GLU 3   113 ?   ?   ?   D . n 
A 1 4   GLN 4   114 ?   ?   ?   D . n 
A 1 5   GLN 5   115 ?   ?   ?   D . n 
A 1 6   LEU 6   116 ?   ?   ?   D . n 
A 1 7   ASN 7   117 ?   ?   ?   D . n 
A 1 8   ILE 8   118 ?   ?   ?   D . n 
A 1 9   THR 9   119 ?   ?   ?   D . n 
A 1 10  ALA 10  120 ?   ?   ?   D . n 
A 1 11  PRO 11  121 ?   ?   ?   D . n 
A 1 12  LYS 12  122 ?   ?   ?   D . n 
A 1 13  ASP 13  123 ?   ?   ?   D . n 
A 1 14  SER 14  124 ?   ?   ?   D . n 
A 1 15  ARG 15  125 ?   ?   ?   D . n 
A 1 16  LEU 16  126 ?   ?   ?   D . n 
A 1 17  ALA 17  127 ?   ?   ?   D . n 
A 1 18  ASN 18  128 ?   ?   ?   D . n 
A 1 19  PRO 19  129 ?   ?   ?   D . n 
A 1 20  THR 20  130 ?   ?   ?   D . n 
A 1 21  ALA 21  131 ?   ?   ?   D . n 
A 1 22  ASP 22  132 ?   ?   ?   D . n 
A 1 23  ASP 23  133 ?   ?   ?   D . n 
A 1 24  PHE 24  134 ?   ?   ?   D . n 
A 1 25  GLN 25  135 ?   ?   ?   D . n 
A 1 26  GLN 26  136 ?   ?   ?   D . n 
A 1 27  GLU 27  137 ?   ?   ?   D . n 
A 1 28  GLU 28  138 ?   ?   ?   D . n 
A 1 29  GLY 29  139 ?   ?   ?   D . n 
A 1 30  PRO 30  140 140 PRO PRO D . n 
A 1 31  LYS 31  141 141 LYS LYS D . n 
A 1 32  ILE 32  142 142 ILE ILE D . n 
A 1 33  THR 33  143 143 THR THR D . n 
A 1 34  LEU 34  144 144 LEU LEU D . n 
A 1 35  LEU 35  145 145 LEU LEU D . n 
A 1 36  THR 36  146 146 THR THR D . n 
A 1 37  LEU 37  147 147 LEU LEU D . n 
A 1 38  ILE 38  148 148 ILE ILE D . n 
A 1 39  LYS 39  149 149 LYS LYS D . n 
A 1 40  THR 40  150 150 THR THR D . n 
A 1 41  ALA 41  151 151 ALA ALA D . n 
A 1 42  GLU 42  152 152 GLU GLU D . n 
A 1 43  HIS 43  153 153 HIS HIS D . n 
A 1 44  TRP 44  154 154 TRP TRP D . n 
A 1 45  ALA 45  155 155 ALA ALA D . n 
A 1 46  ARG 46  156 156 ARG ARG D . n 
A 1 47  GLN 47  157 157 GLN GLN D . n 
A 1 48  ASP 48  158 158 ASP ASP D . n 
A 1 49  ILE 49  159 159 ILE ILE D . n 
A 1 50  ARG 50  160 160 ARG ARG D . n 
A 1 51  THR 51  161 161 THR THR D . n 
A 1 52  ILE 52  162 162 ILE ILE D . n 
A 1 53  GLU 53  163 163 GLU GLU D . n 
A 1 54  ASP 54  164 164 ASP ASP D . n 
A 1 55  SER 55  165 165 SER SER D . n 
A 1 56  LYS 56  166 166 LYS LYS D . n 
A 1 57  LEU 57  167 167 LEU LEU D . n 
A 1 58  ARG 58  168 168 ARG ARG D . n 
A 1 59  ALA 59  169 169 ALA ALA D . n 
A 1 60  LEU 60  170 170 LEU LEU D . n 
A 1 61  LEU 61  171 171 LEU LEU D . n 
A 1 62  THR 62  172 172 THR THR D . n 
A 1 63  LEU 63  173 173 LEU LEU D . n 
A 1 64  CYS 64  174 174 CYS CYS D . n 
A 1 65  ALA 65  175 175 ALA ALA D . n 
A 1 66  VAL 66  176 176 VAL VAL D . n 
A 1 67  MET 67  177 177 MET MET D . n 
A 1 68  THR 68  178 178 THR THR D . n 
A 1 69  ARG 69  179 179 ARG ARG D . n 
A 1 70  LYS 70  180 180 LYS LYS D . n 
A 1 71  PHE 71  181 181 PHE PHE D . n 
A 1 72  SER 72  182 182 SER SER D . n 
A 1 73  LYS 73  183 183 LYS LYS D . n 
A 1 74  SER 74  184 184 SER SER D . n 
A 1 75  GLN 75  185 185 GLN GLN D . n 
A 1 76  LEU 76  186 186 LEU LEU D . n 
A 1 77  SER 77  187 187 SER SER D . n 
A 1 78  LEU 78  188 188 LEU LEU D . n 
A 1 79  LEU 79  189 189 LEU LEU D . n 
A 1 80  CYS 80  190 190 CYS CYS D . n 
A 1 81  GLU 81  191 191 GLU GLU D . n 
A 1 82  THR 82  192 192 THR THR D . n 
A 1 83  HIS 83  193 193 HIS HIS D . n 
A 1 84  LEU 84  194 194 LEU LEU D . n 
A 1 85  ARG 85  195 195 ARG ARG D . n 
A 1 86  ARG 86  196 196 ARG ARG D . n 
A 1 87  GLU 87  197 197 GLU GLU D . n 
A 1 88  GLY 88  198 198 GLY GLY D . n 
A 1 89  LEU 89  199 199 LEU LEU D . n 
A 1 90  GLY 90  200 200 GLY GLY D . n 
A 1 91  GLN 91  201 201 GLN GLN D . n 
A 1 92  ASP 92  202 202 ASP ASP D . n 
A 1 93  GLN 93  203 203 GLN GLN D . n 
A 1 94  ALA 94  204 204 ALA ALA D . n 
A 1 95  GLU 95  205 205 GLU GLU D . n 
A 1 96  PRO 96  206 206 PRO PRO D . n 
A 1 97  VAL 97  207 207 VAL VAL D . n 
A 1 98  LEU 98  208 208 LEU LEU D . n 
A 1 99  GLU 99  209 209 GLU GLU D . n 
A 1 100 VAL 100 210 210 VAL VAL D . n 
A 1 101 TYR 101 211 211 TYR TYR D . n 
A 1 102 GLN 102 212 212 GLN GLN D . n 
A 1 103 ARG 103 213 213 ARG ARG D . n 
A 1 104 LEU 104 214 214 LEU LEU D . n 
A 1 105 HIS 105 215 215 HIS HIS D . n 
A 1 106 SER 106 216 216 SER SER D . n 
A 1 107 ASP 107 217 217 ASP ASP D . n 
A 1 108 LYS 108 218 218 LYS LYS D . n 
A 1 109 GLY 109 219 219 GLY GLY D . n 
A 1 110 GLY 110 220 220 GLY GLY D . n 
A 1 111 SER 111 221 221 SER SER D . n 
A 1 112 PHE 112 222 222 PHE PHE D . n 
A 1 113 GLU 113 223 223 GLU GLU D . n 
A 1 114 ALA 114 224 224 ALA ALA D . n 
A 1 115 ALA 115 225 225 ALA ALA D . n 
A 1 116 LEU 116 226 226 LEU LEU D . n 
A 1 117 TRP 117 227 227 TRP TRP D . n 
A 1 118 GLN 118 228 228 GLN GLN D . n 
A 1 119 GLN 119 229 229 GLN GLN D . n 
A 1 120 TRP 120 230 230 TRP TRP D . n 
A 1 121 ASP 121 231 231 ASP ASP D . n 
A 1 122 ARG 122 232 232 ARG ARG D . n 
A 1 123 GLN 123 233 233 GLN GLN D . n 
A 1 124 SER 124 234 234 SER SER D . n 
A 1 125 LEU 125 235 235 LEU LEU D . n 
A 1 126 ILE 126 236 236 ILE ILE D . n 
A 1 127 MET 127 237 237 MET MET D . n 
A 1 128 PHE 128 238 238 PHE PHE D . n 
A 1 129 ILE 129 239 239 ILE ILE D . n 
A 1 130 THR 130 240 240 THR THR D . n 
A 1 131 ALA 131 241 241 ALA ALA D . n 
A 1 132 PHE 132 242 242 PHE PHE D . n 
A 1 133 LEU 133 243 243 LEU LEU D . n 
A 1 134 ASN 134 244 244 ASN ASN D . n 
A 1 135 ILE 135 245 245 ILE ILE D . n 
A 1 136 ALA 136 246 246 ALA ALA D . n 
A 1 137 LEU 137 247 247 LEU LEU D . n 
A 1 138 GLN 138 248 248 GLN GLN D . n 
A 1 139 LEU 139 249 249 LEU LEU D . n 
A 1 140 PRO 140 250 250 PRO PRO D . n 
A 1 141 CYS 141 251 251 CYS CYS D . n 
A 1 142 GLU 142 252 252 GLU GLU D . n 
A 1 143 SER 143 253 253 SER SER D . n 
A 1 144 SER 144 254 254 SER SER D . n 
A 1 145 ALA 145 255 255 ALA ALA D . n 
A 1 146 VAL 146 256 256 VAL VAL D . n 
A 1 147 VAL 147 257 257 VAL VAL D . n 
A 1 148 VAL 148 258 258 VAL VAL D . n 
A 1 149 SER 149 259 259 SER SER D . n 
A 1 150 GLY 150 260 260 GLY GLY D . n 
A 1 151 LEU 151 261 261 LEU LEU D . n 
A 1 152 ARG 152 262 262 ARG ARG D . n 
A 1 153 THR 153 263 263 THR THR D . n 
A 1 154 LEU 154 264 264 LEU LEU D . n 
A 1 155 VAL 155 265 265 VAL VAL D . n 
A 1 156 PRO 156 266 266 PRO PRO D . n 
A 1 157 GLN 157 267 ?   ?   ?   D . n 
A 1 158 SER 158 268 ?   ?   ?   D . n 
A 1 159 ASP 159 269 ?   ?   ?   D . n 
A 1 160 ASN 160 270 ?   ?   ?   D . n 
A 1 161 GLU 161 271 ?   ?   ?   D . n 
A 1 162 GLU 162 272 ?   ?   ?   D . n 
B 1 1   SER 1   111 ?   ?   ?   A . n 
B 1 2   VAL 2   112 ?   ?   ?   A . n 
B 1 3   GLU 3   113 ?   ?   ?   A . n 
B 1 4   GLN 4   114 ?   ?   ?   A . n 
B 1 5   GLN 5   115 ?   ?   ?   A . n 
B 1 6   LEU 6   116 ?   ?   ?   A . n 
B 1 7   ASN 7   117 ?   ?   ?   A . n 
B 1 8   ILE 8   118 ?   ?   ?   A . n 
B 1 9   THR 9   119 ?   ?   ?   A . n 
B 1 10  ALA 10  120 ?   ?   ?   A . n 
B 1 11  PRO 11  121 ?   ?   ?   A . n 
B 1 12  LYS 12  122 ?   ?   ?   A . n 
B 1 13  ASP 13  123 ?   ?   ?   A . n 
B 1 14  SER 14  124 ?   ?   ?   A . n 
B 1 15  ARG 15  125 ?   ?   ?   A . n 
B 1 16  LEU 16  126 ?   ?   ?   A . n 
B 1 17  ALA 17  127 ?   ?   ?   A . n 
B 1 18  ASN 18  128 ?   ?   ?   A . n 
B 1 19  PRO 19  129 ?   ?   ?   A . n 
B 1 20  THR 20  130 ?   ?   ?   A . n 
B 1 21  ALA 21  131 ?   ?   ?   A . n 
B 1 22  ASP 22  132 ?   ?   ?   A . n 
B 1 23  ASP 23  133 ?   ?   ?   A . n 
B 1 24  PHE 24  134 ?   ?   ?   A . n 
B 1 25  GLN 25  135 ?   ?   ?   A . n 
B 1 26  GLN 26  136 ?   ?   ?   A . n 
B 1 27  GLU 27  137 ?   ?   ?   A . n 
B 1 28  GLU 28  138 ?   ?   ?   A . n 
B 1 29  GLY 29  139 ?   ?   ?   A . n 
B 1 30  PRO 30  140 140 PRO PRO A . n 
B 1 31  LYS 31  141 141 LYS LYS A . n 
B 1 32  ILE 32  142 142 ILE ILE A . n 
B 1 33  THR 33  143 143 THR THR A . n 
B 1 34  LEU 34  144 144 LEU LEU A . n 
B 1 35  LEU 35  145 145 LEU LEU A . n 
B 1 36  THR 36  146 146 THR THR A . n 
B 1 37  LEU 37  147 147 LEU LEU A . n 
B 1 38  ILE 38  148 148 ILE ILE A . n 
B 1 39  LYS 39  149 149 LYS LYS A . n 
B 1 40  THR 40  150 150 THR THR A . n 
B 1 41  ALA 41  151 151 ALA ALA A . n 
B 1 42  GLU 42  152 152 GLU GLU A . n 
B 1 43  HIS 43  153 153 HIS HIS A . n 
B 1 44  TRP 44  154 154 TRP TRP A . n 
B 1 45  ALA 45  155 155 ALA ALA A . n 
B 1 46  ARG 46  156 156 ARG ARG A . n 
B 1 47  GLN 47  157 157 GLN GLN A . n 
B 1 48  ASP 48  158 158 ASP ASP A . n 
B 1 49  ILE 49  159 159 ILE ILE A . n 
B 1 50  ARG 50  160 160 ARG ARG A . n 
B 1 51  THR 51  161 161 THR THR A . n 
B 1 52  ILE 52  162 162 ILE ILE A . n 
B 1 53  GLU 53  163 163 GLU GLU A . n 
B 1 54  ASP 54  164 164 ASP ASP A . n 
B 1 55  SER 55  165 165 SER SER A . n 
B 1 56  LYS 56  166 166 LYS LYS A . n 
B 1 57  LEU 57  167 167 LEU LEU A . n 
B 1 58  ARG 58  168 168 ARG ARG A . n 
B 1 59  ALA 59  169 169 ALA ALA A . n 
B 1 60  LEU 60  170 170 LEU LEU A . n 
B 1 61  LEU 61  171 171 LEU LEU A . n 
B 1 62  THR 62  172 172 THR THR A . n 
B 1 63  LEU 63  173 173 LEU LEU A . n 
B 1 64  CYS 64  174 174 CYS CYS A . n 
B 1 65  ALA 65  175 175 ALA ALA A . n 
B 1 66  VAL 66  176 176 VAL VAL A . n 
B 1 67  MET 67  177 177 MET MET A . n 
B 1 68  THR 68  178 178 THR THR A . n 
B 1 69  ARG 69  179 179 ARG ARG A . n 
B 1 70  LYS 70  180 180 LYS LYS A . n 
B 1 71  PHE 71  181 181 PHE PHE A . n 
B 1 72  SER 72  182 182 SER SER A . n 
B 1 73  LYS 73  183 183 LYS LYS A . n 
B 1 74  SER 74  184 184 SER SER A . n 
B 1 75  GLN 75  185 185 GLN GLN A . n 
B 1 76  LEU 76  186 186 LEU LEU A . n 
B 1 77  SER 77  187 187 SER SER A . n 
B 1 78  LEU 78  188 188 LEU LEU A . n 
B 1 79  LEU 79  189 189 LEU LEU A . n 
B 1 80  CYS 80  190 190 CYS CYS A . n 
B 1 81  GLU 81  191 191 GLU GLU A . n 
B 1 82  THR 82  192 192 THR THR A . n 
B 1 83  HIS 83  193 193 HIS HIS A . n 
B 1 84  LEU 84  194 194 LEU LEU A . n 
B 1 85  ARG 85  195 195 ARG ARG A . n 
B 1 86  ARG 86  196 196 ARG ARG A . n 
B 1 87  GLU 87  197 197 GLU GLU A . n 
B 1 88  GLY 88  198 198 GLY GLY A . n 
B 1 89  LEU 89  199 199 LEU LEU A . n 
B 1 90  GLY 90  200 200 GLY GLY A . n 
B 1 91  GLN 91  201 201 GLN GLN A . n 
B 1 92  ASP 92  202 202 ASP ASP A . n 
B 1 93  GLN 93  203 203 GLN GLN A . n 
B 1 94  ALA 94  204 204 ALA ALA A . n 
B 1 95  GLU 95  205 205 GLU GLU A . n 
B 1 96  PRO 96  206 206 PRO PRO A . n 
B 1 97  VAL 97  207 207 VAL VAL A . n 
B 1 98  LEU 98  208 208 LEU LEU A . n 
B 1 99  GLU 99  209 209 GLU GLU A . n 
B 1 100 VAL 100 210 210 VAL VAL A . n 
B 1 101 TYR 101 211 211 TYR TYR A . n 
B 1 102 GLN 102 212 212 GLN GLN A . n 
B 1 103 ARG 103 213 213 ARG ARG A . n 
B 1 104 LEU 104 214 214 LEU LEU A . n 
B 1 105 HIS 105 215 215 HIS HIS A . n 
B 1 106 SER 106 216 216 SER SER A . n 
B 1 107 ASP 107 217 217 ASP ASP A . n 
B 1 108 LYS 108 218 218 LYS LYS A . n 
B 1 109 GLY 109 219 219 GLY GLY A . n 
B 1 110 GLY 110 220 220 GLY GLY A . n 
B 1 111 SER 111 221 221 SER SER A . n 
B 1 112 PHE 112 222 222 PHE PHE A . n 
B 1 113 GLU 113 223 223 GLU GLU A . n 
B 1 114 ALA 114 224 224 ALA ALA A . n 
B 1 115 ALA 115 225 225 ALA ALA A . n 
B 1 116 LEU 116 226 226 LEU LEU A . n 
B 1 117 TRP 117 227 227 TRP TRP A . n 
B 1 118 GLN 118 228 228 GLN GLN A . n 
B 1 119 GLN 119 229 229 GLN GLN A . n 
B 1 120 TRP 120 230 230 TRP TRP A . n 
B 1 121 ASP 121 231 231 ASP ASP A . n 
B 1 122 ARG 122 232 232 ARG ARG A . n 
B 1 123 GLN 123 233 233 GLN GLN A . n 
B 1 124 SER 124 234 234 SER SER A . n 
B 1 125 LEU 125 235 235 LEU LEU A . n 
B 1 126 ILE 126 236 236 ILE ILE A . n 
B 1 127 MET 127 237 237 MET MET A . n 
B 1 128 PHE 128 238 238 PHE PHE A . n 
B 1 129 ILE 129 239 239 ILE ILE A . n 
B 1 130 THR 130 240 240 THR THR A . n 
B 1 131 ALA 131 241 241 ALA ALA A . n 
B 1 132 PHE 132 242 242 PHE PHE A . n 
B 1 133 LEU 133 243 243 LEU LEU A . n 
B 1 134 ASN 134 244 244 ASN ASN A . n 
B 1 135 ILE 135 245 245 ILE ILE A . n 
B 1 136 ALA 136 246 246 ALA ALA A . n 
B 1 137 LEU 137 247 247 LEU LEU A . n 
B 1 138 GLN 138 248 248 GLN GLN A . n 
B 1 139 LEU 139 249 249 LEU LEU A . n 
B 1 140 PRO 140 250 250 PRO PRO A . n 
B 1 141 CYS 141 251 251 CYS CYS A . n 
B 1 142 GLU 142 252 252 GLU GLU A . n 
B 1 143 SER 143 253 253 SER SER A . n 
B 1 144 SER 144 254 254 SER SER A . n 
B 1 145 ALA 145 255 255 ALA ALA A . n 
B 1 146 VAL 146 256 256 VAL VAL A . n 
B 1 147 VAL 147 257 257 VAL VAL A . n 
B 1 148 VAL 148 258 258 VAL VAL A . n 
B 1 149 SER 149 259 259 SER SER A . n 
B 1 150 GLY 150 260 260 GLY GLY A . n 
B 1 151 LEU 151 261 261 LEU LEU A . n 
B 1 152 ARG 152 262 262 ARG ARG A . n 
B 1 153 THR 153 263 263 THR THR A . n 
B 1 154 LEU 154 264 264 LEU LEU A . n 
B 1 155 VAL 155 265 265 VAL VAL A . n 
B 1 156 PRO 156 266 266 PRO PRO A . n 
B 1 157 GLN 157 267 ?   ?   ?   A . n 
B 1 158 SER 158 268 ?   ?   ?   A . n 
B 1 159 ASP 159 269 ?   ?   ?   A . n 
B 1 160 ASN 160 270 ?   ?   ?   A . n 
B 1 161 GLU 161 271 ?   ?   ?   A . n 
B 1 162 GLU 162 272 ?   ?   ?   A . n 
C 1 1   SER 1   111 ?   ?   ?   B . n 
C 1 2   VAL 2   112 ?   ?   ?   B . n 
C 1 3   GLU 3   113 ?   ?   ?   B . n 
C 1 4   GLN 4   114 ?   ?   ?   B . n 
C 1 5   GLN 5   115 ?   ?   ?   B . n 
C 1 6   LEU 6   116 ?   ?   ?   B . n 
C 1 7   ASN 7   117 ?   ?   ?   B . n 
C 1 8   ILE 8   118 ?   ?   ?   B . n 
C 1 9   THR 9   119 ?   ?   ?   B . n 
C 1 10  ALA 10  120 ?   ?   ?   B . n 
C 1 11  PRO 11  121 ?   ?   ?   B . n 
C 1 12  LYS 12  122 ?   ?   ?   B . n 
C 1 13  ASP 13  123 ?   ?   ?   B . n 
C 1 14  SER 14  124 ?   ?   ?   B . n 
C 1 15  ARG 15  125 ?   ?   ?   B . n 
C 1 16  LEU 16  126 ?   ?   ?   B . n 
C 1 17  ALA 17  127 ?   ?   ?   B . n 
C 1 18  ASN 18  128 ?   ?   ?   B . n 
C 1 19  PRO 19  129 ?   ?   ?   B . n 
C 1 20  THR 20  130 ?   ?   ?   B . n 
C 1 21  ALA 21  131 ?   ?   ?   B . n 
C 1 22  ASP 22  132 ?   ?   ?   B . n 
C 1 23  ASP 23  133 ?   ?   ?   B . n 
C 1 24  PHE 24  134 ?   ?   ?   B . n 
C 1 25  GLN 25  135 ?   ?   ?   B . n 
C 1 26  GLN 26  136 ?   ?   ?   B . n 
C 1 27  GLU 27  137 ?   ?   ?   B . n 
C 1 28  GLU 28  138 ?   ?   ?   B . n 
C 1 29  GLY 29  139 ?   ?   ?   B . n 
C 1 30  PRO 30  140 140 PRO PRO B . n 
C 1 31  LYS 31  141 141 LYS LYS B . n 
C 1 32  ILE 32  142 142 ILE ILE B . n 
C 1 33  THR 33  143 143 THR THR B . n 
C 1 34  LEU 34  144 144 LEU LEU B . n 
C 1 35  LEU 35  145 145 LEU LEU B . n 
C 1 36  THR 36  146 146 THR THR B . n 
C 1 37  LEU 37  147 147 LEU LEU B . n 
C 1 38  ILE 38  148 148 ILE ILE B . n 
C 1 39  LYS 39  149 149 LYS LYS B . n 
C 1 40  THR 40  150 150 THR THR B . n 
C 1 41  ALA 41  151 151 ALA ALA B . n 
C 1 42  GLU 42  152 152 GLU GLU B . n 
C 1 43  HIS 43  153 153 HIS HIS B . n 
C 1 44  TRP 44  154 154 TRP TRP B . n 
C 1 45  ALA 45  155 155 ALA ALA B . n 
C 1 46  ARG 46  156 156 ARG ARG B . n 
C 1 47  GLN 47  157 157 GLN GLN B . n 
C 1 48  ASP 48  158 158 ASP ASP B . n 
C 1 49  ILE 49  159 159 ILE ILE B . n 
C 1 50  ARG 50  160 160 ARG ARG B . n 
C 1 51  THR 51  161 161 THR THR B . n 
C 1 52  ILE 52  162 162 ILE ILE B . n 
C 1 53  GLU 53  163 163 GLU GLU B . n 
C 1 54  ASP 54  164 164 ASP ASP B . n 
C 1 55  SER 55  165 165 SER SER B . n 
C 1 56  LYS 56  166 166 LYS LYS B . n 
C 1 57  LEU 57  167 167 LEU LEU B . n 
C 1 58  ARG 58  168 168 ARG ARG B . n 
C 1 59  ALA 59  169 169 ALA ALA B . n 
C 1 60  LEU 60  170 170 LEU LEU B . n 
C 1 61  LEU 61  171 171 LEU LEU B . n 
C 1 62  THR 62  172 172 THR THR B . n 
C 1 63  LEU 63  173 173 LEU LEU B . n 
C 1 64  CYS 64  174 174 CYS CYS B . n 
C 1 65  ALA 65  175 175 ALA ALA B . n 
C 1 66  VAL 66  176 176 VAL VAL B . n 
C 1 67  MET 67  177 177 MET MET B . n 
C 1 68  THR 68  178 178 THR THR B . n 
C 1 69  ARG 69  179 179 ARG ARG B . n 
C 1 70  LYS 70  180 180 LYS LYS B . n 
C 1 71  PHE 71  181 181 PHE PHE B . n 
C 1 72  SER 72  182 182 SER SER B . n 
C 1 73  LYS 73  183 183 LYS LYS B . n 
C 1 74  SER 74  184 184 SER SER B . n 
C 1 75  GLN 75  185 185 GLN GLN B . n 
C 1 76  LEU 76  186 186 LEU LEU B . n 
C 1 77  SER 77  187 187 SER SER B . n 
C 1 78  LEU 78  188 188 LEU LEU B . n 
C 1 79  LEU 79  189 189 LEU LEU B . n 
C 1 80  CYS 80  190 190 CYS CYS B . n 
C 1 81  GLU 81  191 191 GLU GLU B . n 
C 1 82  THR 82  192 192 THR THR B . n 
C 1 83  HIS 83  193 193 HIS HIS B . n 
C 1 84  LEU 84  194 194 LEU LEU B . n 
C 1 85  ARG 85  195 195 ARG ARG B . n 
C 1 86  ARG 86  196 196 ARG ARG B . n 
C 1 87  GLU 87  197 197 GLU GLU B . n 
C 1 88  GLY 88  198 198 GLY GLY B . n 
C 1 89  LEU 89  199 199 LEU LEU B . n 
C 1 90  GLY 90  200 200 GLY GLY B . n 
C 1 91  GLN 91  201 201 GLN GLN B . n 
C 1 92  ASP 92  202 202 ASP ASP B . n 
C 1 93  GLN 93  203 203 GLN GLN B . n 
C 1 94  ALA 94  204 204 ALA ALA B . n 
C 1 95  GLU 95  205 205 GLU GLU B . n 
C 1 96  PRO 96  206 206 PRO PRO B . n 
C 1 97  VAL 97  207 207 VAL VAL B . n 
C 1 98  LEU 98  208 208 LEU LEU B . n 
C 1 99  GLU 99  209 209 GLU GLU B . n 
C 1 100 VAL 100 210 210 VAL VAL B . n 
C 1 101 TYR 101 211 211 TYR TYR B . n 
C 1 102 GLN 102 212 212 GLN GLN B . n 
C 1 103 ARG 103 213 213 ARG ARG B . n 
C 1 104 LEU 104 214 214 LEU LEU B . n 
C 1 105 HIS 105 215 215 HIS HIS B . n 
C 1 106 SER 106 216 216 SER SER B . n 
C 1 107 ASP 107 217 217 ASP ASP B . n 
C 1 108 LYS 108 218 218 LYS LYS B . n 
C 1 109 GLY 109 219 219 GLY GLY B . n 
C 1 110 GLY 110 220 220 GLY GLY B . n 
C 1 111 SER 111 221 221 SER SER B . n 
C 1 112 PHE 112 222 222 PHE PHE B . n 
C 1 113 GLU 113 223 223 GLU GLU B . n 
C 1 114 ALA 114 224 224 ALA ALA B . n 
C 1 115 ALA 115 225 225 ALA ALA B . n 
C 1 116 LEU 116 226 226 LEU LEU B . n 
C 1 117 TRP 117 227 227 TRP TRP B . n 
C 1 118 GLN 118 228 228 GLN GLN B . n 
C 1 119 GLN 119 229 229 GLN GLN B . n 
C 1 120 TRP 120 230 230 TRP TRP B . n 
C 1 121 ASP 121 231 231 ASP ASP B . n 
C 1 122 ARG 122 232 232 ARG ARG B . n 
C 1 123 GLN 123 233 233 GLN GLN B . n 
C 1 124 SER 124 234 234 SER SER B . n 
C 1 125 LEU 125 235 235 LEU LEU B . n 
C 1 126 ILE 126 236 236 ILE ILE B . n 
C 1 127 MET 127 237 237 MET MET B . n 
C 1 128 PHE 128 238 238 PHE PHE B . n 
C 1 129 ILE 129 239 239 ILE ILE B . n 
C 1 130 THR 130 240 240 THR THR B . n 
C 1 131 ALA 131 241 241 ALA ALA B . n 
C 1 132 PHE 132 242 242 PHE PHE B . n 
C 1 133 LEU 133 243 243 LEU LEU B . n 
C 1 134 ASN 134 244 244 ASN ASN B . n 
C 1 135 ILE 135 245 245 ILE ILE B . n 
C 1 136 ALA 136 246 246 ALA ALA B . n 
C 1 137 LEU 137 247 247 LEU LEU B . n 
C 1 138 GLN 138 248 248 GLN GLN B . n 
C 1 139 LEU 139 249 249 LEU LEU B . n 
C 1 140 PRO 140 250 250 PRO PRO B . n 
C 1 141 CYS 141 251 251 CYS CYS B . n 
C 1 142 GLU 142 252 252 GLU GLU B . n 
C 1 143 SER 143 253 253 SER SER B . n 
C 1 144 SER 144 254 254 SER SER B . n 
C 1 145 ALA 145 255 255 ALA ALA B . n 
C 1 146 VAL 146 256 256 VAL VAL B . n 
C 1 147 VAL 147 257 257 VAL VAL B . n 
C 1 148 VAL 148 258 258 VAL VAL B . n 
C 1 149 SER 149 259 259 SER SER B . n 
C 1 150 GLY 150 260 260 GLY GLY B . n 
C 1 151 LEU 151 261 261 LEU LEU B . n 
C 1 152 ARG 152 262 262 ARG ARG B . n 
C 1 153 THR 153 263 263 THR THR B . n 
C 1 154 LEU 154 264 264 LEU LEU B . n 
C 1 155 VAL 155 265 265 VAL VAL B . n 
C 1 156 PRO 156 266 266 PRO PRO B . n 
C 1 157 GLN 157 267 ?   ?   ?   B . n 
C 1 158 SER 158 268 ?   ?   ?   B . n 
C 1 159 ASP 159 269 ?   ?   ?   B . n 
C 1 160 ASN 160 270 ?   ?   ?   B . n 
C 1 161 GLU 161 271 ?   ?   ?   B . n 
C 1 162 GLU 162 272 ?   ?   ?   B . n 
D 1 1   SER 1   111 ?   ?   ?   C . n 
D 1 2   VAL 2   112 ?   ?   ?   C . n 
D 1 3   GLU 3   113 ?   ?   ?   C . n 
D 1 4   GLN 4   114 ?   ?   ?   C . n 
D 1 5   GLN 5   115 ?   ?   ?   C . n 
D 1 6   LEU 6   116 ?   ?   ?   C . n 
D 1 7   ASN 7   117 ?   ?   ?   C . n 
D 1 8   ILE 8   118 ?   ?   ?   C . n 
D 1 9   THR 9   119 ?   ?   ?   C . n 
D 1 10  ALA 10  120 ?   ?   ?   C . n 
D 1 11  PRO 11  121 ?   ?   ?   C . n 
D 1 12  LYS 12  122 ?   ?   ?   C . n 
D 1 13  ASP 13  123 ?   ?   ?   C . n 
D 1 14  SER 14  124 ?   ?   ?   C . n 
D 1 15  ARG 15  125 ?   ?   ?   C . n 
D 1 16  LEU 16  126 ?   ?   ?   C . n 
D 1 17  ALA 17  127 ?   ?   ?   C . n 
D 1 18  ASN 18  128 ?   ?   ?   C . n 
D 1 19  PRO 19  129 ?   ?   ?   C . n 
D 1 20  THR 20  130 ?   ?   ?   C . n 
D 1 21  ALA 21  131 ?   ?   ?   C . n 
D 1 22  ASP 22  132 ?   ?   ?   C . n 
D 1 23  ASP 23  133 ?   ?   ?   C . n 
D 1 24  PHE 24  134 ?   ?   ?   C . n 
D 1 25  GLN 25  135 ?   ?   ?   C . n 
D 1 26  GLN 26  136 ?   ?   ?   C . n 
D 1 27  GLU 27  137 ?   ?   ?   C . n 
D 1 28  GLU 28  138 ?   ?   ?   C . n 
D 1 29  GLY 29  139 ?   ?   ?   C . n 
D 1 30  PRO 30  140 140 PRO PRO C . n 
D 1 31  LYS 31  141 141 LYS LYS C . n 
D 1 32  ILE 32  142 142 ILE ILE C . n 
D 1 33  THR 33  143 143 THR THR C . n 
D 1 34  LEU 34  144 144 LEU LEU C . n 
D 1 35  LEU 35  145 145 LEU LEU C . n 
D 1 36  THR 36  146 146 THR THR C . n 
D 1 37  LEU 37  147 147 LEU LEU C . n 
D 1 38  ILE 38  148 148 ILE ILE C . n 
D 1 39  LYS 39  149 149 LYS LYS C . n 
D 1 40  THR 40  150 150 THR THR C . n 
D 1 41  ALA 41  151 151 ALA ALA C . n 
D 1 42  GLU 42  152 152 GLU GLU C . n 
D 1 43  HIS 43  153 153 HIS HIS C . n 
D 1 44  TRP 44  154 154 TRP TRP C . n 
D 1 45  ALA 45  155 155 ALA ALA C . n 
D 1 46  ARG 46  156 156 ARG ARG C . n 
D 1 47  GLN 47  157 157 GLN GLN C . n 
D 1 48  ASP 48  158 158 ASP ASP C . n 
D 1 49  ILE 49  159 159 ILE ILE C . n 
D 1 50  ARG 50  160 160 ARG ARG C . n 
D 1 51  THR 51  161 161 THR THR C . n 
D 1 52  ILE 52  162 162 ILE ILE C . n 
D 1 53  GLU 53  163 163 GLU GLU C . n 
D 1 54  ASP 54  164 164 ASP ASP C . n 
D 1 55  SER 55  165 165 SER SER C . n 
D 1 56  LYS 56  166 166 LYS LYS C . n 
D 1 57  LEU 57  167 167 LEU LEU C . n 
D 1 58  ARG 58  168 168 ARG ARG C . n 
D 1 59  ALA 59  169 169 ALA ALA C . n 
D 1 60  LEU 60  170 170 LEU LEU C . n 
D 1 61  LEU 61  171 171 LEU LEU C . n 
D 1 62  THR 62  172 172 THR THR C . n 
D 1 63  LEU 63  173 173 LEU LEU C . n 
D 1 64  CYS 64  174 174 CYS CYS C . n 
D 1 65  ALA 65  175 175 ALA ALA C . n 
D 1 66  VAL 66  176 176 VAL VAL C . n 
D 1 67  MET 67  177 177 MET MET C . n 
D 1 68  THR 68  178 178 THR THR C . n 
D 1 69  ARG 69  179 179 ARG ARG C . n 
D 1 70  LYS 70  180 180 LYS LYS C . n 
D 1 71  PHE 71  181 181 PHE PHE C . n 
D 1 72  SER 72  182 182 SER SER C . n 
D 1 73  LYS 73  183 183 LYS LYS C . n 
D 1 74  SER 74  184 184 SER SER C . n 
D 1 75  GLN 75  185 185 GLN GLN C . n 
D 1 76  LEU 76  186 186 LEU LEU C . n 
D 1 77  SER 77  187 187 SER SER C . n 
D 1 78  LEU 78  188 188 LEU LEU C . n 
D 1 79  LEU 79  189 189 LEU LEU C . n 
D 1 80  CYS 80  190 190 CYS CYS C . n 
D 1 81  GLU 81  191 191 GLU GLU C . n 
D 1 82  THR 82  192 192 THR THR C . n 
D 1 83  HIS 83  193 193 HIS HIS C . n 
D 1 84  LEU 84  194 194 LEU LEU C . n 
D 1 85  ARG 85  195 195 ARG ARG C . n 
D 1 86  ARG 86  196 196 ARG ARG C . n 
D 1 87  GLU 87  197 197 GLU GLU C . n 
D 1 88  GLY 88  198 198 GLY GLY C . n 
D 1 89  LEU 89  199 199 LEU LEU C . n 
D 1 90  GLY 90  200 200 GLY GLY C . n 
D 1 91  GLN 91  201 201 GLN GLN C . n 
D 1 92  ASP 92  202 202 ASP ASP C . n 
D 1 93  GLN 93  203 203 GLN GLN C . n 
D 1 94  ALA 94  204 204 ALA ALA C . n 
D 1 95  GLU 95  205 205 GLU GLU C . n 
D 1 96  PRO 96  206 206 PRO PRO C . n 
D 1 97  VAL 97  207 207 VAL VAL C . n 
D 1 98  LEU 98  208 208 LEU LEU C . n 
D 1 99  GLU 99  209 209 GLU GLU C . n 
D 1 100 VAL 100 210 210 VAL VAL C . n 
D 1 101 TYR 101 211 211 TYR TYR C . n 
D 1 102 GLN 102 212 212 GLN GLN C . n 
D 1 103 ARG 103 213 213 ARG ARG C . n 
D 1 104 LEU 104 214 214 LEU LEU C . n 
D 1 105 HIS 105 215 215 HIS HIS C . n 
D 1 106 SER 106 216 216 SER SER C . n 
D 1 107 ASP 107 217 217 ASP ASP C . n 
D 1 108 LYS 108 218 218 LYS LYS C . n 
D 1 109 GLY 109 219 219 GLY GLY C . n 
D 1 110 GLY 110 220 220 GLY GLY C . n 
D 1 111 SER 111 221 221 SER SER C . n 
D 1 112 PHE 112 222 222 PHE PHE C . n 
D 1 113 GLU 113 223 223 GLU GLU C . n 
D 1 114 ALA 114 224 224 ALA ALA C . n 
D 1 115 ALA 115 225 225 ALA ALA C . n 
D 1 116 LEU 116 226 226 LEU LEU C . n 
D 1 117 TRP 117 227 227 TRP TRP C . n 
D 1 118 GLN 118 228 228 GLN GLN C . n 
D 1 119 GLN 119 229 229 GLN GLN C . n 
D 1 120 TRP 120 230 230 TRP TRP C . n 
D 1 121 ASP 121 231 231 ASP ASP C . n 
D 1 122 ARG 122 232 232 ARG ARG C . n 
D 1 123 GLN 123 233 233 GLN GLN C . n 
D 1 124 SER 124 234 234 SER SER C . n 
D 1 125 LEU 125 235 235 LEU LEU C . n 
D 1 126 ILE 126 236 236 ILE ILE C . n 
D 1 127 MET 127 237 237 MET MET C . n 
D 1 128 PHE 128 238 238 PHE PHE C . n 
D 1 129 ILE 129 239 239 ILE ILE C . n 
D 1 130 THR 130 240 240 THR THR C . n 
D 1 131 ALA 131 241 241 ALA ALA C . n 
D 1 132 PHE 132 242 242 PHE PHE C . n 
D 1 133 LEU 133 243 243 LEU LEU C . n 
D 1 134 ASN 134 244 244 ASN ASN C . n 
D 1 135 ILE 135 245 245 ILE ILE C . n 
D 1 136 ALA 136 246 246 ALA ALA C . n 
D 1 137 LEU 137 247 247 LEU LEU C . n 
D 1 138 GLN 138 248 248 GLN GLN C . n 
D 1 139 LEU 139 249 249 LEU LEU C . n 
D 1 140 PRO 140 250 250 PRO PRO C . n 
D 1 141 CYS 141 251 251 CYS CYS C . n 
D 1 142 GLU 142 252 252 GLU GLU C . n 
D 1 143 SER 143 253 253 SER SER C . n 
D 1 144 SER 144 254 254 SER SER C . n 
D 1 145 ALA 145 255 255 ALA ALA C . n 
D 1 146 VAL 146 256 256 VAL VAL C . n 
D 1 147 VAL 147 257 257 VAL VAL C . n 
D 1 148 VAL 148 258 258 VAL VAL C . n 
D 1 149 SER 149 259 259 SER SER C . n 
D 1 150 GLY 150 260 260 GLY GLY C . n 
D 1 151 LEU 151 261 261 LEU LEU C . n 
D 1 152 ARG 152 262 262 ARG ARG C . n 
D 1 153 THR 153 263 263 THR THR C . n 
D 1 154 LEU 154 264 264 LEU LEU C . n 
D 1 155 VAL 155 265 265 VAL VAL C . n 
D 1 156 PRO 156 266 266 PRO PRO C . n 
D 1 157 GLN 157 267 ?   ?   ?   C . n 
D 1 158 SER 158 268 ?   ?   ?   C . n 
D 1 159 ASP 159 269 ?   ?   ?   C . n 
D 1 160 ASN 160 270 ?   ?   ?   C . n 
D 1 161 GLU 161 271 ?   ?   ?   C . n 
D 1 162 GLU 162 272 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1ECX 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1ECX 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 A1ECX 1  301 1   A1ECX LIG D . 
F 2 A1ECX 1  302 2   A1ECX LIG D . 
G 3 CL    1  303 1   CL    CL  D . 
H 3 CL    1  304 2   CL    CL  D . 
I 3 CL    1  301 3   CL    CL  A . 
J 4 HOH   1  401 132 HOH   HOH D . 
J 4 HOH   2  402 31  HOH   HOH D . 
J 4 HOH   3  403 32  HOH   HOH D . 
J 4 HOH   4  404 59  HOH   HOH D . 
J 4 HOH   5  405 103 HOH   HOH D . 
J 4 HOH   6  406 129 HOH   HOH D . 
J 4 HOH   7  407 141 HOH   HOH D . 
J 4 HOH   8  408 14  HOH   HOH D . 
J 4 HOH   9  409 93  HOH   HOH D . 
J 4 HOH   10 410 8   HOH   HOH D . 
J 4 HOH   11 411 82  HOH   HOH D . 
J 4 HOH   12 412 53  HOH   HOH D . 
J 4 HOH   13 413 61  HOH   HOH D . 
J 4 HOH   14 414 124 HOH   HOH D . 
J 4 HOH   15 415 125 HOH   HOH D . 
J 4 HOH   16 416 25  HOH   HOH D . 
J 4 HOH   17 417 13  HOH   HOH D . 
J 4 HOH   18 418 44  HOH   HOH D . 
J 4 HOH   19 419 34  HOH   HOH D . 
J 4 HOH   20 420 12  HOH   HOH D . 
J 4 HOH   21 421 55  HOH   HOH D . 
J 4 HOH   22 422 58  HOH   HOH D . 
J 4 HOH   23 423 116 HOH   HOH D . 
J 4 HOH   24 424 127 HOH   HOH D . 
J 4 HOH   25 425 90  HOH   HOH D . 
J 4 HOH   26 426 17  HOH   HOH D . 
J 4 HOH   27 427 137 HOH   HOH D . 
J 4 HOH   28 428 91  HOH   HOH D . 
J 4 HOH   29 429 38  HOH   HOH D . 
J 4 HOH   30 430 78  HOH   HOH D . 
J 4 HOH   31 431 92  HOH   HOH D . 
J 4 HOH   32 432 122 HOH   HOH D . 
J 4 HOH   33 433 110 HOH   HOH D . 
J 4 HOH   34 434 144 HOH   HOH D . 
J 4 HOH   35 435 70  HOH   HOH D . 
K 4 HOH   1  401 83  HOH   HOH A . 
K 4 HOH   2  402 60  HOH   HOH A . 
K 4 HOH   3  403 56  HOH   HOH A . 
K 4 HOH   4  404 41  HOH   HOH A . 
K 4 HOH   5  405 20  HOH   HOH A . 
K 4 HOH   6  406 4   HOH   HOH A . 
K 4 HOH   7  407 42  HOH   HOH A . 
K 4 HOH   8  408 15  HOH   HOH A . 
K 4 HOH   9  409 1   HOH   HOH A . 
K 4 HOH   10 410 68  HOH   HOH A . 
K 4 HOH   11 411 106 HOH   HOH A . 
K 4 HOH   12 412 97  HOH   HOH A . 
K 4 HOH   13 413 39  HOH   HOH A . 
K 4 HOH   14 414 131 HOH   HOH A . 
K 4 HOH   15 415 10  HOH   HOH A . 
K 4 HOH   16 416 114 HOH   HOH A . 
K 4 HOH   17 417 45  HOH   HOH A . 
K 4 HOH   18 418 130 HOH   HOH A . 
K 4 HOH   19 419 136 HOH   HOH A . 
K 4 HOH   20 420 24  HOH   HOH A . 
K 4 HOH   21 421 113 HOH   HOH A . 
K 4 HOH   22 422 49  HOH   HOH A . 
K 4 HOH   23 423 6   HOH   HOH A . 
K 4 HOH   24 424 146 HOH   HOH A . 
K 4 HOH   25 425 99  HOH   HOH A . 
K 4 HOH   26 426 87  HOH   HOH A . 
K 4 HOH   27 427 112 HOH   HOH A . 
K 4 HOH   28 428 86  HOH   HOH A . 
K 4 HOH   29 429 75  HOH   HOH A . 
K 4 HOH   30 430 2   HOH   HOH A . 
K 4 HOH   31 431 126 HOH   HOH A . 
K 4 HOH   32 432 77  HOH   HOH A . 
K 4 HOH   33 433 111 HOH   HOH A . 
K 4 HOH   34 434 62  HOH   HOH A . 
K 4 HOH   35 435 143 HOH   HOH A . 
K 4 HOH   36 436 74  HOH   HOH A . 
K 4 HOH   37 437 43  HOH   HOH A . 
K 4 HOH   38 438 71  HOH   HOH A . 
K 4 HOH   39 439 123 HOH   HOH A . 
L 4 HOH   1  301 23  HOH   HOH B . 
L 4 HOH   2  302 16  HOH   HOH B . 
L 4 HOH   3  303 18  HOH   HOH B . 
L 4 HOH   4  304 21  HOH   HOH B . 
L 4 HOH   5  305 105 HOH   HOH B . 
L 4 HOH   6  306 36  HOH   HOH B . 
L 4 HOH   7  307 66  HOH   HOH B . 
L 4 HOH   8  308 54  HOH   HOH B . 
L 4 HOH   9  309 47  HOH   HOH B . 
L 4 HOH   10 310 138 HOH   HOH B . 
L 4 HOH   11 311 9   HOH   HOH B . 
L 4 HOH   12 312 101 HOH   HOH B . 
L 4 HOH   13 313 95  HOH   HOH B . 
L 4 HOH   14 314 19  HOH   HOH B . 
L 4 HOH   15 315 27  HOH   HOH B . 
L 4 HOH   16 316 72  HOH   HOH B . 
L 4 HOH   17 317 89  HOH   HOH B . 
L 4 HOH   18 318 63  HOH   HOH B . 
L 4 HOH   19 319 81  HOH   HOH B . 
L 4 HOH   20 320 85  HOH   HOH B . 
L 4 HOH   21 321 35  HOH   HOH B . 
L 4 HOH   22 322 108 HOH   HOH B . 
L 4 HOH   23 323 96  HOH   HOH B . 
L 4 HOH   24 324 37  HOH   HOH B . 
L 4 HOH   25 325 67  HOH   HOH B . 
L 4 HOH   26 326 107 HOH   HOH B . 
L 4 HOH   27 327 48  HOH   HOH B . 
L 4 HOH   28 328 65  HOH   HOH B . 
L 4 HOH   29 329 80  HOH   HOH B . 
L 4 HOH   30 330 120 HOH   HOH B . 
L 4 HOH   31 331 98  HOH   HOH B . 
L 4 HOH   32 332 94  HOH   HOH B . 
L 4 HOH   33 333 109 HOH   HOH B . 
L 4 HOH   34 334 145 HOH   HOH B . 
L 4 HOH   35 335 134 HOH   HOH B . 
L 4 HOH   36 336 149 HOH   HOH B . 
M 4 HOH   1  301 104 HOH   HOH C . 
M 4 HOH   2  302 5   HOH   HOH C . 
M 4 HOH   3  303 26  HOH   HOH C . 
M 4 HOH   4  304 140 HOH   HOH C . 
M 4 HOH   5  305 50  HOH   HOH C . 
M 4 HOH   6  306 57  HOH   HOH C . 
M 4 HOH   7  307 133 HOH   HOH C . 
M 4 HOH   8  308 119 HOH   HOH C . 
M 4 HOH   9  309 30  HOH   HOH C . 
M 4 HOH   10 310 115 HOH   HOH C . 
M 4 HOH   11 311 148 HOH   HOH C . 
M 4 HOH   12 312 22  HOH   HOH C . 
M 4 HOH   13 313 139 HOH   HOH C . 
M 4 HOH   14 314 76  HOH   HOH C . 
M 4 HOH   15 315 117 HOH   HOH C . 
M 4 HOH   16 316 69  HOH   HOH C . 
M 4 HOH   17 317 84  HOH   HOH C . 
M 4 HOH   18 318 3   HOH   HOH C . 
M 4 HOH   19 319 28  HOH   HOH C . 
M 4 HOH   20 320 29  HOH   HOH C . 
M 4 HOH   21 321 46  HOH   HOH C . 
M 4 HOH   22 322 33  HOH   HOH C . 
M 4 HOH   23 323 135 HOH   HOH C . 
M 4 HOH   24 324 64  HOH   HOH C . 
M 4 HOH   25 325 142 HOH   HOH C . 
M 4 HOH   26 326 73  HOH   HOH C . 
M 4 HOH   27 327 51  HOH   HOH C . 
M 4 HOH   28 328 121 HOH   HOH C . 
M 4 HOH   29 329 40  HOH   HOH C . 
M 4 HOH   30 330 7   HOH   HOH C . 
M 4 HOH   31 331 88  HOH   HOH C . 
M 4 HOH   32 332 11  HOH   HOH C . 
M 4 HOH   33 333 100 HOH   HOH C . 
M 4 HOH   34 334 118 HOH   HOH C . 
M 4 HOH   35 335 147 HOH   HOH C . 
M 4 HOH   36 336 102 HOH   HOH C . 
M 4 HOH   37 337 52  HOH   HOH C . 
M 4 HOH   38 338 128 HOH   HOH C . 
M 4 HOH   39 339 79  HOH   HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0425 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  72.880 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   85.961 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  71.779 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JQK 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     46.177 
_cell.length_a_esd                 ? 
_cell.length_b                     54.042 
_cell.length_b_esd                 ? 
_cell.length_c                     83.265 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JQK 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JQK 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.58 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.26 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '20% PEG3350 and 200 mM ammonium phosphate dibasic' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 S 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-12-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97915 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL10U2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97915 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL10U2 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9JQK 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.29 
_reflns.d_resolution_low                               79.55 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     31319 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           95.2 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                1.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          2.4 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.546 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.099 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.29 
_reflns_shell.d_res_low                                     2.37 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3107 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.547 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          95.5 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.004 
_refine.aniso_B[1][2]                            0.007 
_refine.aniso_B[1][3]                            -0.005 
_refine.aniso_B[2][2]                            0.014 
_refine.aniso_B[2][3]                            -0.002 
_refine.aniso_B[3][3]                            -0.008 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               45.408 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.936 
_refine.correlation_coeff_Fo_to_Fc_free          0.911 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9JQK 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.290 
_refine.ls_d_res_low                             48.52 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     29773 
_refine.ls_number_reflns_R_free                  1546 
_refine.ls_number_reflns_R_work                  29773 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.14 
_refine.ls_percent_reflns_R_free                 4.936 
_refine.ls_R_factor_all                          0.221 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2638 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2184 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.298 
_refine.pdbx_overall_ESU_R_Free                  0.236 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             11.425 
_refine.overall_SU_ML                            0.260 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.290 
_refine_hist.d_res_low                        48.52 
_refine_hist.number_atoms_solvent             149 
_refine_hist.number_atoms_total               4246 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4040 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         57 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.005  0.012  4162  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  4160  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 0.620  1.839  5618  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.247  1.755  9556  ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 4.596  5.000  504   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 5.076  5.500  40    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 11.868 10.000 772   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 9.794  10.000 172   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.033  0.200  664   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.191  0.200  4     ? r_chiral_restr_other           ? ? 
'X-RAY DIFFRACTION' ? 0.005  0.020  4830  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.020  954   ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.201  1.000  926   ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.186  1.000  3579  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.167  1.000  2069  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.067  1.000  1960  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.141  1.000  164   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.029  1.000  1     ? r_symmetry_xyhbond_nbd_other   ? ? 
'X-RAY DIFFRACTION' ? 0.176  1.000  10    ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.154  1.000  79    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.118  1.000  5     ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 4.083  4.245  2028  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.073  4.245  2028  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 5.667  7.654  2528  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 5.666  7.654  2529  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 5.984  5.006  2134  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 5.982  5.008  2135  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 8.982  8.892  3090  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 8.981  8.893  3091  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 10.684 52.520 16838 ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 10.685 52.491 16777 ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.290  2.349  . . 102 2244 95.3271 . . . . 0.333 . . . . . . . . . . . 0.340 
'X-RAY DIFFRACTION' 2.349  2.414  . . 111 2149 95.7627 . . . . 0.328 . . . . . . . . . . . 0.361 
'X-RAY DIFFRACTION' 2.414  2.483  . . 123 2105 96.8696 . . . . 0.302 . . . . . . . . . . . 0.340 
'X-RAY DIFFRACTION' 2.483  2.560  . . 125 2090 97.7062 . . . . 0.272 . . . . . . . . . . . 0.295 
'X-RAY DIFFRACTION' 2.560  2.643  . . 108 1960 97.8240 . . . . 0.242 . . . . . . . . . . . 0.279 
'X-RAY DIFFRACTION' 2.643  2.736  . . 83  1999 97.7465 . . . . 0.237 . . . . . . . . . . . 0.260 
'X-RAY DIFFRACTION' 2.736  2.839  . . 100 1880 97.8744 . . . . 0.230 . . . . . . . . . . . 0.313 
'X-RAY DIFFRACTION' 2.839  2.954  . . 88  1813 97.8888 . . . . 0.225 . . . . . . . . . . . 0.282 
'X-RAY DIFFRACTION' 2.954  3.085  . . 64  1784 98.2456 . . . . 0.208 . . . . . . . . . . . 0.270 
'X-RAY DIFFRACTION' 3.085  3.235  . . 80  1660 98.6395 . . . . 0.210 . . . . . . . . . . . 0.236 
'X-RAY DIFFRACTION' 3.235  3.409  . . 80  1584 97.9976 . . . . 0.196 . . . . . . . . . . . 0.300 
'X-RAY DIFFRACTION' 3.409  3.615  . . 70  1300 84.5157 . . . . 0.192 . . . . . . . . . . . 0.208 
'X-RAY DIFFRACTION' 3.615  3.863  . . 56  1081 74.6553 . . . . 0.196 . . . . . . . . . . . 0.252 
'X-RAY DIFFRACTION' 3.863  4.170  . . 54  1053 78.6780 . . . . 0.186 . . . . . . . . . . . 0.232 
'X-RAY DIFFRACTION' 4.170  4.565  . . 75  1188 98.7490 . . . . 0.184 . . . . . . . . . . . 0.268 
'X-RAY DIFFRACTION' 4.565  5.098  . . 69  1090 99.2295 . . . . 0.162 . . . . . . . . . . . 0.198 
'X-RAY DIFFRACTION' 5.098  5.876  . . 54  976  98.9433 . . . . 0.209 . . . . . . . . . . . 0.259 
'X-RAY DIFFRACTION' 5.876  7.170  . . 53  801  99.3023 . . . . 0.238 . . . . . . . . . . . 0.243 
'X-RAY DIFFRACTION' 7.170  10.031 . . 26  655  99.4161 . . . . 0.182 . . . . . . . . . . . 0.200 
'X-RAY DIFFRACTION' 10.031 48.52  . . 25  355  97.9381 . . . . 0.326 . . . . . . . . . . . 0.375 
# 
_struct.entry_id                     9JQK 
_struct.title                        'Ebola VP30 and its inhibitor' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JQK 
_struct_keywords.text            'VP30, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    VP30_EBOZ5 
_struct_ref.pdbx_db_accession          Q77DJ5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SVEQQLNITAPKDSRLANPTADDFQQEEGPKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLC
ETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVPQSDN
EE
;
_struct_ref.pdbx_align_begin           111 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JQK D 1 ? 162 ? Q77DJ5 111 ? 272 ? 111 272 
2 1 9JQK A 1 ? 162 ? Q77DJ5 111 ? 272 ? 111 272 
3 1 9JQK B 1 ? 162 ? Q77DJ5 111 ? 272 ? 111 272 
4 1 9JQK C 1 ? 162 ? Q77DJ5 111 ? 272 ? 111 272 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3800  ? 
1 MORE         -52   ? 
1 'SSA (A^2)'  13100 ? 
2 'ABSA (A^2)' 3610  ? 
2 MORE         -43   ? 
2 'SSA (A^2)'  12430 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F,G,H,I,J,K 
2 1 D,M               
2 2 C,L               
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z   1.0000000000 0.0000000000 0.0000000000 0.0000000000  0.0000000000 1.0000000000 
0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000   
2 'crystal symmetry operation' 1_554 x,y,z-1 1.0000000000 0.0000000000 0.0000000000 -5.8648100625 0.0000000000 1.0000000000 
0.0000000000 -23.8743381429 0.0000000000 0.0000000000 1.0000000000 -79.5530024963 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 33  ? ARG A 46  ? THR D 143 ARG D 156 1 ? 14 
HELX_P HELX_P2  AA2 GLU A 53  ? ARG A 69  ? GLU D 163 ARG D 179 1 ? 17 
HELX_P HELX_P3  AA3 LYS A 70  ? PHE A 71  ? LYS D 180 PHE D 181 5 ? 2  
HELX_P HELX_P4  AA4 SER A 72  ? SER A 74  ? SER D 182 SER D 184 5 ? 3  
HELX_P HELX_P5  AA5 GLN A 75  ? GLY A 88  ? GLN D 185 GLY D 198 1 ? 14 
HELX_P HELX_P6  AA6 GLY A 90  ? ASP A 92  ? GLY D 200 ASP D 202 5 ? 3  
HELX_P HELX_P7  AA7 GLN A 93  ? SER A 106 ? GLN D 203 SER D 216 1 ? 14 
HELX_P HELX_P8  AA8 GLY A 110 ? TRP A 120 ? GLY D 220 TRP D 230 1 ? 11 
HELX_P HELX_P9  AA9 ASP A 121 ? LEU A 137 ? ASP D 231 LEU D 247 1 ? 17 
HELX_P HELX_P10 AB1 SER A 144 ? THR A 153 ? SER D 254 THR D 263 1 ? 10 
HELX_P HELX_P11 AB2 THR B 33  ? GLN B 47  ? THR A 143 GLN A 157 1 ? 15 
HELX_P HELX_P12 AB3 GLU B 53  ? ARG B 69  ? GLU A 163 ARG A 179 1 ? 17 
HELX_P HELX_P13 AB4 LYS B 70  ? PHE B 71  ? LYS A 180 PHE A 181 5 ? 2  
HELX_P HELX_P14 AB5 SER B 72  ? SER B 74  ? SER A 182 SER A 184 5 ? 3  
HELX_P HELX_P15 AB6 GLN B 75  ? GLY B 88  ? GLN A 185 GLY A 198 1 ? 14 
HELX_P HELX_P16 AB7 GLY B 90  ? ASP B 92  ? GLY A 200 ASP A 202 5 ? 3  
HELX_P HELX_P17 AB8 GLN B 93  ? SER B 106 ? GLN A 203 SER A 216 1 ? 14 
HELX_P HELX_P18 AB9 GLY B 110 ? TRP B 120 ? GLY A 220 TRP A 230 1 ? 11 
HELX_P HELX_P19 AC1 ASP B 121 ? LEU B 137 ? ASP A 231 LEU A 247 1 ? 17 
HELX_P HELX_P20 AC2 SER B 144 ? THR B 153 ? SER A 254 THR A 263 1 ? 10 
HELX_P HELX_P21 AC3 THR C 33  ? ALA C 45  ? THR B 143 ALA B 155 1 ? 13 
HELX_P HELX_P22 AC4 GLU C 53  ? ARG C 69  ? GLU B 163 ARG B 179 1 ? 17 
HELX_P HELX_P23 AC5 LYS C 70  ? PHE C 71  ? LYS B 180 PHE B 181 5 ? 2  
HELX_P HELX_P24 AC6 SER C 72  ? SER C 74  ? SER B 182 SER B 184 5 ? 3  
HELX_P HELX_P25 AC7 GLN C 75  ? GLY C 88  ? GLN B 185 GLY B 198 1 ? 14 
HELX_P HELX_P26 AC8 GLY C 90  ? ASP C 92  ? GLY B 200 ASP B 202 5 ? 3  
HELX_P HELX_P27 AC9 GLN C 93  ? SER C 106 ? GLN B 203 SER B 216 1 ? 14 
HELX_P HELX_P28 AD1 GLY C 110 ? TRP C 120 ? GLY B 220 TRP B 230 1 ? 11 
HELX_P HELX_P29 AD2 ASP C 121 ? LEU C 137 ? ASP B 231 LEU B 247 1 ? 17 
HELX_P HELX_P30 AD3 SER C 144 ? THR C 153 ? SER B 254 THR B 263 1 ? 10 
HELX_P HELX_P31 AD4 THR D 33  ? GLN D 47  ? THR C 143 GLN C 157 1 ? 15 
HELX_P HELX_P32 AD5 GLU D 53  ? ARG D 69  ? GLU C 163 ARG C 179 1 ? 17 
HELX_P HELX_P33 AD6 LYS D 70  ? PHE D 71  ? LYS C 180 PHE C 181 5 ? 2  
HELX_P HELX_P34 AD7 SER D 72  ? SER D 74  ? SER C 182 SER C 184 5 ? 3  
HELX_P HELX_P35 AD8 GLN D 75  ? GLY D 88  ? GLN C 185 GLY C 198 1 ? 14 
HELX_P HELX_P36 AD9 GLY D 90  ? ASP D 92  ? GLY C 200 ASP C 202 5 ? 3  
HELX_P HELX_P37 AE1 GLN D 93  ? SER D 106 ? GLN C 203 SER C 216 1 ? 14 
HELX_P HELX_P38 AE2 GLY D 110 ? TRP D 120 ? GLY C 220 TRP C 230 1 ? 11 
HELX_P HELX_P39 AE3 ASP D 121 ? LEU D 137 ? ASP C 231 LEU C 247 1 ? 17 
HELX_P HELX_P40 AE4 SER D 144 ? THR D 153 ? SER C 254 THR C 263 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9JQK 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 THR A 161 ? ? 85.92  5.71   
2 1 SER C 254 ? ? -38.75 128.58 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       336 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   7.10 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 D SER 111 ? A SER 1   
2   1 Y 1 D VAL 112 ? A VAL 2   
3   1 Y 1 D GLU 113 ? A GLU 3   
4   1 Y 1 D GLN 114 ? A GLN 4   
5   1 Y 1 D GLN 115 ? A GLN 5   
6   1 Y 1 D LEU 116 ? A LEU 6   
7   1 Y 1 D ASN 117 ? A ASN 7   
8   1 Y 1 D ILE 118 ? A ILE 8   
9   1 Y 1 D THR 119 ? A THR 9   
10  1 Y 1 D ALA 120 ? A ALA 10  
11  1 Y 1 D PRO 121 ? A PRO 11  
12  1 Y 1 D LYS 122 ? A LYS 12  
13  1 Y 1 D ASP 123 ? A ASP 13  
14  1 Y 1 D SER 124 ? A SER 14  
15  1 Y 1 D ARG 125 ? A ARG 15  
16  1 Y 1 D LEU 126 ? A LEU 16  
17  1 Y 1 D ALA 127 ? A ALA 17  
18  1 Y 1 D ASN 128 ? A ASN 18  
19  1 Y 1 D PRO 129 ? A PRO 19  
20  1 Y 1 D THR 130 ? A THR 20  
21  1 Y 1 D ALA 131 ? A ALA 21  
22  1 Y 1 D ASP 132 ? A ASP 22  
23  1 Y 1 D ASP 133 ? A ASP 23  
24  1 Y 1 D PHE 134 ? A PHE 24  
25  1 Y 1 D GLN 135 ? A GLN 25  
26  1 Y 1 D GLN 136 ? A GLN 26  
27  1 Y 1 D GLU 137 ? A GLU 27  
28  1 Y 1 D GLU 138 ? A GLU 28  
29  1 Y 1 D GLY 139 ? A GLY 29  
30  1 Y 1 D GLN 267 ? A GLN 157 
31  1 Y 1 D SER 268 ? A SER 158 
32  1 Y 1 D ASP 269 ? A ASP 159 
33  1 Y 1 D ASN 270 ? A ASN 160 
34  1 Y 1 D GLU 271 ? A GLU 161 
35  1 Y 1 D GLU 272 ? A GLU 162 
36  1 Y 1 A SER 111 ? B SER 1   
37  1 Y 1 A VAL 112 ? B VAL 2   
38  1 Y 1 A GLU 113 ? B GLU 3   
39  1 Y 1 A GLN 114 ? B GLN 4   
40  1 Y 1 A GLN 115 ? B GLN 5   
41  1 Y 1 A LEU 116 ? B LEU 6   
42  1 Y 1 A ASN 117 ? B ASN 7   
43  1 Y 1 A ILE 118 ? B ILE 8   
44  1 Y 1 A THR 119 ? B THR 9   
45  1 Y 1 A ALA 120 ? B ALA 10  
46  1 Y 1 A PRO 121 ? B PRO 11  
47  1 Y 1 A LYS 122 ? B LYS 12  
48  1 Y 1 A ASP 123 ? B ASP 13  
49  1 Y 1 A SER 124 ? B SER 14  
50  1 Y 1 A ARG 125 ? B ARG 15  
51  1 Y 1 A LEU 126 ? B LEU 16  
52  1 Y 1 A ALA 127 ? B ALA 17  
53  1 Y 1 A ASN 128 ? B ASN 18  
54  1 Y 1 A PRO 129 ? B PRO 19  
55  1 Y 1 A THR 130 ? B THR 20  
56  1 Y 1 A ALA 131 ? B ALA 21  
57  1 Y 1 A ASP 132 ? B ASP 22  
58  1 Y 1 A ASP 133 ? B ASP 23  
59  1 Y 1 A PHE 134 ? B PHE 24  
60  1 Y 1 A GLN 135 ? B GLN 25  
61  1 Y 1 A GLN 136 ? B GLN 26  
62  1 Y 1 A GLU 137 ? B GLU 27  
63  1 Y 1 A GLU 138 ? B GLU 28  
64  1 Y 1 A GLY 139 ? B GLY 29  
65  1 Y 1 A GLN 267 ? B GLN 157 
66  1 Y 1 A SER 268 ? B SER 158 
67  1 Y 1 A ASP 269 ? B ASP 159 
68  1 Y 1 A ASN 270 ? B ASN 160 
69  1 Y 1 A GLU 271 ? B GLU 161 
70  1 Y 1 A GLU 272 ? B GLU 162 
71  1 Y 1 B SER 111 ? C SER 1   
72  1 Y 1 B VAL 112 ? C VAL 2   
73  1 Y 1 B GLU 113 ? C GLU 3   
74  1 Y 1 B GLN 114 ? C GLN 4   
75  1 Y 1 B GLN 115 ? C GLN 5   
76  1 Y 1 B LEU 116 ? C LEU 6   
77  1 Y 1 B ASN 117 ? C ASN 7   
78  1 Y 1 B ILE 118 ? C ILE 8   
79  1 Y 1 B THR 119 ? C THR 9   
80  1 Y 1 B ALA 120 ? C ALA 10  
81  1 Y 1 B PRO 121 ? C PRO 11  
82  1 Y 1 B LYS 122 ? C LYS 12  
83  1 Y 1 B ASP 123 ? C ASP 13  
84  1 Y 1 B SER 124 ? C SER 14  
85  1 Y 1 B ARG 125 ? C ARG 15  
86  1 Y 1 B LEU 126 ? C LEU 16  
87  1 Y 1 B ALA 127 ? C ALA 17  
88  1 Y 1 B ASN 128 ? C ASN 18  
89  1 Y 1 B PRO 129 ? C PRO 19  
90  1 Y 1 B THR 130 ? C THR 20  
91  1 Y 1 B ALA 131 ? C ALA 21  
92  1 Y 1 B ASP 132 ? C ASP 22  
93  1 Y 1 B ASP 133 ? C ASP 23  
94  1 Y 1 B PHE 134 ? C PHE 24  
95  1 Y 1 B GLN 135 ? C GLN 25  
96  1 Y 1 B GLN 136 ? C GLN 26  
97  1 Y 1 B GLU 137 ? C GLU 27  
98  1 Y 1 B GLU 138 ? C GLU 28  
99  1 Y 1 B GLY 139 ? C GLY 29  
100 1 Y 1 B GLN 267 ? C GLN 157 
101 1 Y 1 B SER 268 ? C SER 158 
102 1 Y 1 B ASP 269 ? C ASP 159 
103 1 Y 1 B ASN 270 ? C ASN 160 
104 1 Y 1 B GLU 271 ? C GLU 161 
105 1 Y 1 B GLU 272 ? C GLU 162 
106 1 Y 1 C SER 111 ? D SER 1   
107 1 Y 1 C VAL 112 ? D VAL 2   
108 1 Y 1 C GLU 113 ? D GLU 3   
109 1 Y 1 C GLN 114 ? D GLN 4   
110 1 Y 1 C GLN 115 ? D GLN 5   
111 1 Y 1 C LEU 116 ? D LEU 6   
112 1 Y 1 C ASN 117 ? D ASN 7   
113 1 Y 1 C ILE 118 ? D ILE 8   
114 1 Y 1 C THR 119 ? D THR 9   
115 1 Y 1 C ALA 120 ? D ALA 10  
116 1 Y 1 C PRO 121 ? D PRO 11  
117 1 Y 1 C LYS 122 ? D LYS 12  
118 1 Y 1 C ASP 123 ? D ASP 13  
119 1 Y 1 C SER 124 ? D SER 14  
120 1 Y 1 C ARG 125 ? D ARG 15  
121 1 Y 1 C LEU 126 ? D LEU 16  
122 1 Y 1 C ALA 127 ? D ALA 17  
123 1 Y 1 C ASN 128 ? D ASN 18  
124 1 Y 1 C PRO 129 ? D PRO 19  
125 1 Y 1 C THR 130 ? D THR 20  
126 1 Y 1 C ALA 131 ? D ALA 21  
127 1 Y 1 C ASP 132 ? D ASP 22  
128 1 Y 1 C ASP 133 ? D ASP 23  
129 1 Y 1 C PHE 134 ? D PHE 24  
130 1 Y 1 C GLN 135 ? D GLN 25  
131 1 Y 1 C GLN 136 ? D GLN 26  
132 1 Y 1 C GLU 137 ? D GLU 27  
133 1 Y 1 C GLU 138 ? D GLU 28  
134 1 Y 1 C GLY 139 ? D GLY 29  
135 1 Y 1 C GLN 267 ? D GLN 157 
136 1 Y 1 C SER 268 ? D SER 158 
137 1 Y 1 C ASP 269 ? D ASP 159 
138 1 Y 1 C ASN 270 ? D ASN 160 
139 1 Y 1 C GLU 271 ? D GLU 161 
140 1 Y 1 C GLU 272 ? D GLU 162 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1ECX C4   C  Y N 1   
A1ECX C5   C  Y N 2   
A1ECX C6   C  Y N 3   
A1ECX C7   C  Y N 4   
A1ECX C8   C  N N 5   
A1ECX C10  C  N N 6   
A1ECX C13  C  N N 7   
A1ECX C15  C  N N 8   
A1ECX C17  C  N N 9   
A1ECX C20  C  N N 10  
A1ECX C21  C  N N 11  
A1ECX C22  C  N N 12  
A1ECX C24  C  N N 13  
A1ECX O1   O  N N 14  
A1ECX C1   C  N N 15  
A1ECX C2   C  Y N 16  
A1ECX C3   C  Y N 17  
A1ECX O2   O  N N 18  
A1ECX C9   C  N N 19  
A1ECX C11  C  N N 20  
A1ECX C12  C  N N 21  
A1ECX C14  C  N N 22  
A1ECX C16  C  N N 23  
A1ECX C18  C  N N 24  
A1ECX C19  C  N N 25  
A1ECX C23  C  N N 26  
A1ECX O3   O  N N 27  
A1ECX H1   H  N N 28  
A1ECX H2   H  N N 29  
A1ECX H3   H  N N 30  
A1ECX H5   H  N N 31  
A1ECX H6   H  N N 32  
A1ECX H10  H  N N 33  
A1ECX H9   H  N N 34  
A1ECX H15  H  N N 35  
A1ECX H16  H  N N 36  
A1ECX H20  H  N N 37  
A1ECX H19  H  N N 38  
A1ECX H23  H  N N 39  
A1ECX H27  H  N N 40  
A1ECX H28  H  N N 41  
A1ECX H30  H  N N 42  
A1ECX H29  H  N N 43  
A1ECX H31  H  N N 44  
A1ECX H32  H  N N 45  
A1ECX H36  H  N N 46  
A1ECX H35  H  N N 47  
A1ECX H37  H  N N 48  
A1ECX H4   H  N N 49  
A1ECX H7   H  N N 50  
A1ECX H8   H  N N 51  
A1ECX H11  H  N N 52  
A1ECX H12  H  N N 53  
A1ECX H14  H  N N 54  
A1ECX H13  H  N N 55  
A1ECX H18  H  N N 56  
A1ECX H17  H  N N 57  
A1ECX H21  H  N N 58  
A1ECX H22  H  N N 59  
A1ECX H24  H  N N 60  
A1ECX H25  H  N N 61  
A1ECX H26  H  N N 62  
A1ECX H34  H  N N 63  
A1ECX H33  H  N N 64  
A1ECX H38  H  N N 65  
ALA   N    N  N N 66  
ALA   CA   C  N S 67  
ALA   C    C  N N 68  
ALA   O    O  N N 69  
ALA   CB   C  N N 70  
ALA   OXT  O  N N 71  
ALA   H    H  N N 72  
ALA   H2   H  N N 73  
ALA   HA   H  N N 74  
ALA   HB1  H  N N 75  
ALA   HB2  H  N N 76  
ALA   HB3  H  N N 77  
ALA   HXT  H  N N 78  
ARG   N    N  N N 79  
ARG   CA   C  N S 80  
ARG   C    C  N N 81  
ARG   O    O  N N 82  
ARG   CB   C  N N 83  
ARG   CG   C  N N 84  
ARG   CD   C  N N 85  
ARG   NE   N  N N 86  
ARG   CZ   C  N N 87  
ARG   NH1  N  N N 88  
ARG   NH2  N  N N 89  
ARG   OXT  O  N N 90  
ARG   H    H  N N 91  
ARG   H2   H  N N 92  
ARG   HA   H  N N 93  
ARG   HB2  H  N N 94  
ARG   HB3  H  N N 95  
ARG   HG2  H  N N 96  
ARG   HG3  H  N N 97  
ARG   HD2  H  N N 98  
ARG   HD3  H  N N 99  
ARG   HE   H  N N 100 
ARG   HH11 H  N N 101 
ARG   HH12 H  N N 102 
ARG   HH21 H  N N 103 
ARG   HH22 H  N N 104 
ARG   HXT  H  N N 105 
ASN   N    N  N N 106 
ASN   CA   C  N S 107 
ASN   C    C  N N 108 
ASN   O    O  N N 109 
ASN   CB   C  N N 110 
ASN   CG   C  N N 111 
ASN   OD1  O  N N 112 
ASN   ND2  N  N N 113 
ASN   OXT  O  N N 114 
ASN   H    H  N N 115 
ASN   H2   H  N N 116 
ASN   HA   H  N N 117 
ASN   HB2  H  N N 118 
ASN   HB3  H  N N 119 
ASN   HD21 H  N N 120 
ASN   HD22 H  N N 121 
ASN   HXT  H  N N 122 
ASP   N    N  N N 123 
ASP   CA   C  N S 124 
ASP   C    C  N N 125 
ASP   O    O  N N 126 
ASP   CB   C  N N 127 
ASP   CG   C  N N 128 
ASP   OD1  O  N N 129 
ASP   OD2  O  N N 130 
ASP   OXT  O  N N 131 
ASP   H    H  N N 132 
ASP   H2   H  N N 133 
ASP   HA   H  N N 134 
ASP   HB2  H  N N 135 
ASP   HB3  H  N N 136 
ASP   HD2  H  N N 137 
ASP   HXT  H  N N 138 
CL    CL   CL N N 139 
CYS   N    N  N N 140 
CYS   CA   C  N R 141 
CYS   C    C  N N 142 
CYS   O    O  N N 143 
CYS   CB   C  N N 144 
CYS   SG   S  N N 145 
CYS   OXT  O  N N 146 
CYS   H    H  N N 147 
CYS   H2   H  N N 148 
CYS   HA   H  N N 149 
CYS   HB2  H  N N 150 
CYS   HB3  H  N N 151 
CYS   HG   H  N N 152 
CYS   HXT  H  N N 153 
GLN   N    N  N N 154 
GLN   CA   C  N S 155 
GLN   C    C  N N 156 
GLN   O    O  N N 157 
GLN   CB   C  N N 158 
GLN   CG   C  N N 159 
GLN   CD   C  N N 160 
GLN   OE1  O  N N 161 
GLN   NE2  N  N N 162 
GLN   OXT  O  N N 163 
GLN   H    H  N N 164 
GLN   H2   H  N N 165 
GLN   HA   H  N N 166 
GLN   HB2  H  N N 167 
GLN   HB3  H  N N 168 
GLN   HG2  H  N N 169 
GLN   HG3  H  N N 170 
GLN   HE21 H  N N 171 
GLN   HE22 H  N N 172 
GLN   HXT  H  N N 173 
GLU   N    N  N N 174 
GLU   CA   C  N S 175 
GLU   C    C  N N 176 
GLU   O    O  N N 177 
GLU   CB   C  N N 178 
GLU   CG   C  N N 179 
GLU   CD   C  N N 180 
GLU   OE1  O  N N 181 
GLU   OE2  O  N N 182 
GLU   OXT  O  N N 183 
GLU   H    H  N N 184 
GLU   H2   H  N N 185 
GLU   HA   H  N N 186 
GLU   HB2  H  N N 187 
GLU   HB3  H  N N 188 
GLU   HG2  H  N N 189 
GLU   HG3  H  N N 190 
GLU   HE2  H  N N 191 
GLU   HXT  H  N N 192 
GLY   N    N  N N 193 
GLY   CA   C  N N 194 
GLY   C    C  N N 195 
GLY   O    O  N N 196 
GLY   OXT  O  N N 197 
GLY   H    H  N N 198 
GLY   H2   H  N N 199 
GLY   HA2  H  N N 200 
GLY   HA3  H  N N 201 
GLY   HXT  H  N N 202 
HIS   N    N  N N 203 
HIS   CA   C  N S 204 
HIS   C    C  N N 205 
HIS   O    O  N N 206 
HIS   CB   C  N N 207 
HIS   CG   C  Y N 208 
HIS   ND1  N  Y N 209 
HIS   CD2  C  Y N 210 
HIS   CE1  C  Y N 211 
HIS   NE2  N  Y N 212 
HIS   OXT  O  N N 213 
HIS   H    H  N N 214 
HIS   H2   H  N N 215 
HIS   HA   H  N N 216 
HIS   HB2  H  N N 217 
HIS   HB3  H  N N 218 
HIS   HD1  H  N N 219 
HIS   HD2  H  N N 220 
HIS   HE1  H  N N 221 
HIS   HE2  H  N N 222 
HIS   HXT  H  N N 223 
HOH   O    O  N N 224 
HOH   H1   H  N N 225 
HOH   H2   H  N N 226 
ILE   N    N  N N 227 
ILE   CA   C  N S 228 
ILE   C    C  N N 229 
ILE   O    O  N N 230 
ILE   CB   C  N S 231 
ILE   CG1  C  N N 232 
ILE   CG2  C  N N 233 
ILE   CD1  C  N N 234 
ILE   OXT  O  N N 235 
ILE   H    H  N N 236 
ILE   H2   H  N N 237 
ILE   HA   H  N N 238 
ILE   HB   H  N N 239 
ILE   HG12 H  N N 240 
ILE   HG13 H  N N 241 
ILE   HG21 H  N N 242 
ILE   HG22 H  N N 243 
ILE   HG23 H  N N 244 
ILE   HD11 H  N N 245 
ILE   HD12 H  N N 246 
ILE   HD13 H  N N 247 
ILE   HXT  H  N N 248 
LEU   N    N  N N 249 
LEU   CA   C  N S 250 
LEU   C    C  N N 251 
LEU   O    O  N N 252 
LEU   CB   C  N N 253 
LEU   CG   C  N N 254 
LEU   CD1  C  N N 255 
LEU   CD2  C  N N 256 
LEU   OXT  O  N N 257 
LEU   H    H  N N 258 
LEU   H2   H  N N 259 
LEU   HA   H  N N 260 
LEU   HB2  H  N N 261 
LEU   HB3  H  N N 262 
LEU   HG   H  N N 263 
LEU   HD11 H  N N 264 
LEU   HD12 H  N N 265 
LEU   HD13 H  N N 266 
LEU   HD21 H  N N 267 
LEU   HD22 H  N N 268 
LEU   HD23 H  N N 269 
LEU   HXT  H  N N 270 
LYS   N    N  N N 271 
LYS   CA   C  N S 272 
LYS   C    C  N N 273 
LYS   O    O  N N 274 
LYS   CB   C  N N 275 
LYS   CG   C  N N 276 
LYS   CD   C  N N 277 
LYS   CE   C  N N 278 
LYS   NZ   N  N N 279 
LYS   OXT  O  N N 280 
LYS   H    H  N N 281 
LYS   H2   H  N N 282 
LYS   HA   H  N N 283 
LYS   HB2  H  N N 284 
LYS   HB3  H  N N 285 
LYS   HG2  H  N N 286 
LYS   HG3  H  N N 287 
LYS   HD2  H  N N 288 
LYS   HD3  H  N N 289 
LYS   HE2  H  N N 290 
LYS   HE3  H  N N 291 
LYS   HZ1  H  N N 292 
LYS   HZ2  H  N N 293 
LYS   HZ3  H  N N 294 
LYS   HXT  H  N N 295 
MET   N    N  N N 296 
MET   CA   C  N S 297 
MET   C    C  N N 298 
MET   O    O  N N 299 
MET   CB   C  N N 300 
MET   CG   C  N N 301 
MET   SD   S  N N 302 
MET   CE   C  N N 303 
MET   OXT  O  N N 304 
MET   H    H  N N 305 
MET   H2   H  N N 306 
MET   HA   H  N N 307 
MET   HB2  H  N N 308 
MET   HB3  H  N N 309 
MET   HG2  H  N N 310 
MET   HG3  H  N N 311 
MET   HE1  H  N N 312 
MET   HE2  H  N N 313 
MET   HE3  H  N N 314 
MET   HXT  H  N N 315 
PHE   N    N  N N 316 
PHE   CA   C  N S 317 
PHE   C    C  N N 318 
PHE   O    O  N N 319 
PHE   CB   C  N N 320 
PHE   CG   C  Y N 321 
PHE   CD1  C  Y N 322 
PHE   CD2  C  Y N 323 
PHE   CE1  C  Y N 324 
PHE   CE2  C  Y N 325 
PHE   CZ   C  Y N 326 
PHE   OXT  O  N N 327 
PHE   H    H  N N 328 
PHE   H2   H  N N 329 
PHE   HA   H  N N 330 
PHE   HB2  H  N N 331 
PHE   HB3  H  N N 332 
PHE   HD1  H  N N 333 
PHE   HD2  H  N N 334 
PHE   HE1  H  N N 335 
PHE   HE2  H  N N 336 
PHE   HZ   H  N N 337 
PHE   HXT  H  N N 338 
PRO   N    N  N N 339 
PRO   CA   C  N S 340 
PRO   C    C  N N 341 
PRO   O    O  N N 342 
PRO   CB   C  N N 343 
PRO   CG   C  N N 344 
PRO   CD   C  N N 345 
PRO   OXT  O  N N 346 
PRO   H    H  N N 347 
PRO   HA   H  N N 348 
PRO   HB2  H  N N 349 
PRO   HB3  H  N N 350 
PRO   HG2  H  N N 351 
PRO   HG3  H  N N 352 
PRO   HD2  H  N N 353 
PRO   HD3  H  N N 354 
PRO   HXT  H  N N 355 
SER   N    N  N N 356 
SER   CA   C  N S 357 
SER   C    C  N N 358 
SER   O    O  N N 359 
SER   CB   C  N N 360 
SER   OG   O  N N 361 
SER   OXT  O  N N 362 
SER   H    H  N N 363 
SER   H2   H  N N 364 
SER   HA   H  N N 365 
SER   HB2  H  N N 366 
SER   HB3  H  N N 367 
SER   HG   H  N N 368 
SER   HXT  H  N N 369 
THR   N    N  N N 370 
THR   CA   C  N S 371 
THR   C    C  N N 372 
THR   O    O  N N 373 
THR   CB   C  N R 374 
THR   OG1  O  N N 375 
THR   CG2  C  N N 376 
THR   OXT  O  N N 377 
THR   H    H  N N 378 
THR   H2   H  N N 379 
THR   HA   H  N N 380 
THR   HB   H  N N 381 
THR   HG1  H  N N 382 
THR   HG21 H  N N 383 
THR   HG22 H  N N 384 
THR   HG23 H  N N 385 
THR   HXT  H  N N 386 
TRP   N    N  N N 387 
TRP   CA   C  N S 388 
TRP   C    C  N N 389 
TRP   O    O  N N 390 
TRP   CB   C  N N 391 
TRP   CG   C  Y N 392 
TRP   CD1  C  Y N 393 
TRP   CD2  C  Y N 394 
TRP   NE1  N  Y N 395 
TRP   CE2  C  Y N 396 
TRP   CE3  C  Y N 397 
TRP   CZ2  C  Y N 398 
TRP   CZ3  C  Y N 399 
TRP   CH2  C  Y N 400 
TRP   OXT  O  N N 401 
TRP   H    H  N N 402 
TRP   H2   H  N N 403 
TRP   HA   H  N N 404 
TRP   HB2  H  N N 405 
TRP   HB3  H  N N 406 
TRP   HD1  H  N N 407 
TRP   HE1  H  N N 408 
TRP   HE3  H  N N 409 
TRP   HZ2  H  N N 410 
TRP   HZ3  H  N N 411 
TRP   HH2  H  N N 412 
TRP   HXT  H  N N 413 
TYR   N    N  N N 414 
TYR   CA   C  N S 415 
TYR   C    C  N N 416 
TYR   O    O  N N 417 
TYR   CB   C  N N 418 
TYR   CG   C  Y N 419 
TYR   CD1  C  Y N 420 
TYR   CD2  C  Y N 421 
TYR   CE1  C  Y N 422 
TYR   CE2  C  Y N 423 
TYR   CZ   C  Y N 424 
TYR   OH   O  N N 425 
TYR   OXT  O  N N 426 
TYR   H    H  N N 427 
TYR   H2   H  N N 428 
TYR   HA   H  N N 429 
TYR   HB2  H  N N 430 
TYR   HB3  H  N N 431 
TYR   HD1  H  N N 432 
TYR   HD2  H  N N 433 
TYR   HE1  H  N N 434 
TYR   HE2  H  N N 435 
TYR   HH   H  N N 436 
TYR   HXT  H  N N 437 
VAL   N    N  N N 438 
VAL   CA   C  N S 439 
VAL   C    C  N N 440 
VAL   O    O  N N 441 
VAL   CB   C  N N 442 
VAL   CG1  C  N N 443 
VAL   CG2  C  N N 444 
VAL   OXT  O  N N 445 
VAL   H    H  N N 446 
VAL   H2   H  N N 447 
VAL   HA   H  N N 448 
VAL   HB   H  N N 449 
VAL   HG11 H  N N 450 
VAL   HG12 H  N N 451 
VAL   HG13 H  N N 452 
VAL   HG21 H  N N 453 
VAL   HG22 H  N N 454 
VAL   HG23 H  N N 455 
VAL   HXT  H  N N 456 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1ECX O1  C1   doub N N 1   
A1ECX C1  C2   sing N N 2   
A1ECX C2  C3   doub Y N 3   
A1ECX C3  C4   sing Y N 4   
A1ECX C4  C5   doub Y N 5   
A1ECX C5  C6   sing Y N 6   
A1ECX C6  C7   doub Y N 7   
A1ECX C7  O2   sing N N 8   
A1ECX C3  C8   sing N N 9   
A1ECX C8  C9   sing N N 10  
A1ECX C9  C10  sing N N 11  
A1ECX C10 C11  sing N N 12  
A1ECX C11 C12  sing N N 13  
A1ECX C12 C13  sing N N 14  
A1ECX C13 C14  sing N N 15  
A1ECX C14 C15  sing N N 16  
A1ECX C15 C16  sing N N 17  
A1ECX C16 C17  sing N N 18  
A1ECX C17 C18  doub N E 19  
A1ECX C18 C19  sing N N 20  
A1ECX C19 C20  sing N N 21  
A1ECX C20 C21  sing N N 22  
A1ECX C21 C22  sing N N 23  
A1ECX C22 C23  sing N N 24  
A1ECX C23 C24  sing N N 25  
A1ECX C1  O3   sing N N 26  
A1ECX C2  C7   sing Y N 27  
A1ECX C4  H1   sing N N 28  
A1ECX C5  H2   sing N N 29  
A1ECX C6  H3   sing N N 30  
A1ECX C8  H5   sing N N 31  
A1ECX C8  H6   sing N N 32  
A1ECX C10 H10  sing N N 33  
A1ECX C10 H9   sing N N 34  
A1ECX C13 H15  sing N N 35  
A1ECX C13 H16  sing N N 36  
A1ECX C15 H20  sing N N 37  
A1ECX C15 H19  sing N N 38  
A1ECX C17 H23  sing N N 39  
A1ECX C20 H27  sing N N 40  
A1ECX C20 H28  sing N N 41  
A1ECX C21 H30  sing N N 42  
A1ECX C21 H29  sing N N 43  
A1ECX C22 H31  sing N N 44  
A1ECX C22 H32  sing N N 45  
A1ECX C24 H36  sing N N 46  
A1ECX C24 H35  sing N N 47  
A1ECX C24 H37  sing N N 48  
A1ECX O2  H4   sing N N 49  
A1ECX C9  H7   sing N N 50  
A1ECX C9  H8   sing N N 51  
A1ECX C11 H11  sing N N 52  
A1ECX C11 H12  sing N N 53  
A1ECX C12 H14  sing N N 54  
A1ECX C12 H13  sing N N 55  
A1ECX C14 H18  sing N N 56  
A1ECX C14 H17  sing N N 57  
A1ECX C16 H21  sing N N 58  
A1ECX C16 H22  sing N N 59  
A1ECX C18 H24  sing N N 60  
A1ECX C19 H25  sing N N 61  
A1ECX C19 H26  sing N N 62  
A1ECX C23 H34  sing N N 63  
A1ECX C23 H33  sing N N 64  
A1ECX O3  H38  sing N N 65  
ALA   N   CA   sing N N 66  
ALA   N   H    sing N N 67  
ALA   N   H2   sing N N 68  
ALA   CA  C    sing N N 69  
ALA   CA  CB   sing N N 70  
ALA   CA  HA   sing N N 71  
ALA   C   O    doub N N 72  
ALA   C   OXT  sing N N 73  
ALA   CB  HB1  sing N N 74  
ALA   CB  HB2  sing N N 75  
ALA   CB  HB3  sing N N 76  
ALA   OXT HXT  sing N N 77  
ARG   N   CA   sing N N 78  
ARG   N   H    sing N N 79  
ARG   N   H2   sing N N 80  
ARG   CA  C    sing N N 81  
ARG   CA  CB   sing N N 82  
ARG   CA  HA   sing N N 83  
ARG   C   O    doub N N 84  
ARG   C   OXT  sing N N 85  
ARG   CB  CG   sing N N 86  
ARG   CB  HB2  sing N N 87  
ARG   CB  HB3  sing N N 88  
ARG   CG  CD   sing N N 89  
ARG   CG  HG2  sing N N 90  
ARG   CG  HG3  sing N N 91  
ARG   CD  NE   sing N N 92  
ARG   CD  HD2  sing N N 93  
ARG   CD  HD3  sing N N 94  
ARG   NE  CZ   sing N N 95  
ARG   NE  HE   sing N N 96  
ARG   CZ  NH1  sing N N 97  
ARG   CZ  NH2  doub N N 98  
ARG   NH1 HH11 sing N N 99  
ARG   NH1 HH12 sing N N 100 
ARG   NH2 HH21 sing N N 101 
ARG   NH2 HH22 sing N N 102 
ARG   OXT HXT  sing N N 103 
ASN   N   CA   sing N N 104 
ASN   N   H    sing N N 105 
ASN   N   H2   sing N N 106 
ASN   CA  C    sing N N 107 
ASN   CA  CB   sing N N 108 
ASN   CA  HA   sing N N 109 
ASN   C   O    doub N N 110 
ASN   C   OXT  sing N N 111 
ASN   CB  CG   sing N N 112 
ASN   CB  HB2  sing N N 113 
ASN   CB  HB3  sing N N 114 
ASN   CG  OD1  doub N N 115 
ASN   CG  ND2  sing N N 116 
ASN   ND2 HD21 sing N N 117 
ASN   ND2 HD22 sing N N 118 
ASN   OXT HXT  sing N N 119 
ASP   N   CA   sing N N 120 
ASP   N   H    sing N N 121 
ASP   N   H2   sing N N 122 
ASP   CA  C    sing N N 123 
ASP   CA  CB   sing N N 124 
ASP   CA  HA   sing N N 125 
ASP   C   O    doub N N 126 
ASP   C   OXT  sing N N 127 
ASP   CB  CG   sing N N 128 
ASP   CB  HB2  sing N N 129 
ASP   CB  HB3  sing N N 130 
ASP   CG  OD1  doub N N 131 
ASP   CG  OD2  sing N N 132 
ASP   OD2 HD2  sing N N 133 
ASP   OXT HXT  sing N N 134 
CYS   N   CA   sing N N 135 
CYS   N   H    sing N N 136 
CYS   N   H2   sing N N 137 
CYS   CA  C    sing N N 138 
CYS   CA  CB   sing N N 139 
CYS   CA  HA   sing N N 140 
CYS   C   O    doub N N 141 
CYS   C   OXT  sing N N 142 
CYS   CB  SG   sing N N 143 
CYS   CB  HB2  sing N N 144 
CYS   CB  HB3  sing N N 145 
CYS   SG  HG   sing N N 146 
CYS   OXT HXT  sing N N 147 
GLN   N   CA   sing N N 148 
GLN   N   H    sing N N 149 
GLN   N   H2   sing N N 150 
GLN   CA  C    sing N N 151 
GLN   CA  CB   sing N N 152 
GLN   CA  HA   sing N N 153 
GLN   C   O    doub N N 154 
GLN   C   OXT  sing N N 155 
GLN   CB  CG   sing N N 156 
GLN   CB  HB2  sing N N 157 
GLN   CB  HB3  sing N N 158 
GLN   CG  CD   sing N N 159 
GLN   CG  HG2  sing N N 160 
GLN   CG  HG3  sing N N 161 
GLN   CD  OE1  doub N N 162 
GLN   CD  NE2  sing N N 163 
GLN   NE2 HE21 sing N N 164 
GLN   NE2 HE22 sing N N 165 
GLN   OXT HXT  sing N N 166 
GLU   N   CA   sing N N 167 
GLU   N   H    sing N N 168 
GLU   N   H2   sing N N 169 
GLU   CA  C    sing N N 170 
GLU   CA  CB   sing N N 171 
GLU   CA  HA   sing N N 172 
GLU   C   O    doub N N 173 
GLU   C   OXT  sing N N 174 
GLU   CB  CG   sing N N 175 
GLU   CB  HB2  sing N N 176 
GLU   CB  HB3  sing N N 177 
GLU   CG  CD   sing N N 178 
GLU   CG  HG2  sing N N 179 
GLU   CG  HG3  sing N N 180 
GLU   CD  OE1  doub N N 181 
GLU   CD  OE2  sing N N 182 
GLU   OE2 HE2  sing N N 183 
GLU   OXT HXT  sing N N 184 
GLY   N   CA   sing N N 185 
GLY   N   H    sing N N 186 
GLY   N   H2   sing N N 187 
GLY   CA  C    sing N N 188 
GLY   CA  HA2  sing N N 189 
GLY   CA  HA3  sing N N 190 
GLY   C   O    doub N N 191 
GLY   C   OXT  sing N N 192 
GLY   OXT HXT  sing N N 193 
HIS   N   CA   sing N N 194 
HIS   N   H    sing N N 195 
HIS   N   H2   sing N N 196 
HIS   CA  C    sing N N 197 
HIS   CA  CB   sing N N 198 
HIS   CA  HA   sing N N 199 
HIS   C   O    doub N N 200 
HIS   C   OXT  sing N N 201 
HIS   CB  CG   sing N N 202 
HIS   CB  HB2  sing N N 203 
HIS   CB  HB3  sing N N 204 
HIS   CG  ND1  sing Y N 205 
HIS   CG  CD2  doub Y N 206 
HIS   ND1 CE1  doub Y N 207 
HIS   ND1 HD1  sing N N 208 
HIS   CD2 NE2  sing Y N 209 
HIS   CD2 HD2  sing N N 210 
HIS   CE1 NE2  sing Y N 211 
HIS   CE1 HE1  sing N N 212 
HIS   NE2 HE2  sing N N 213 
HIS   OXT HXT  sing N N 214 
HOH   O   H1   sing N N 215 
HOH   O   H2   sing N N 216 
ILE   N   CA   sing N N 217 
ILE   N   H    sing N N 218 
ILE   N   H2   sing N N 219 
ILE   CA  C    sing N N 220 
ILE   CA  CB   sing N N 221 
ILE   CA  HA   sing N N 222 
ILE   C   O    doub N N 223 
ILE   C   OXT  sing N N 224 
ILE   CB  CG1  sing N N 225 
ILE   CB  CG2  sing N N 226 
ILE   CB  HB   sing N N 227 
ILE   CG1 CD1  sing N N 228 
ILE   CG1 HG12 sing N N 229 
ILE   CG1 HG13 sing N N 230 
ILE   CG2 HG21 sing N N 231 
ILE   CG2 HG22 sing N N 232 
ILE   CG2 HG23 sing N N 233 
ILE   CD1 HD11 sing N N 234 
ILE   CD1 HD12 sing N N 235 
ILE   CD1 HD13 sing N N 236 
ILE   OXT HXT  sing N N 237 
LEU   N   CA   sing N N 238 
LEU   N   H    sing N N 239 
LEU   N   H2   sing N N 240 
LEU   CA  C    sing N N 241 
LEU   CA  CB   sing N N 242 
LEU   CA  HA   sing N N 243 
LEU   C   O    doub N N 244 
LEU   C   OXT  sing N N 245 
LEU   CB  CG   sing N N 246 
LEU   CB  HB2  sing N N 247 
LEU   CB  HB3  sing N N 248 
LEU   CG  CD1  sing N N 249 
LEU   CG  CD2  sing N N 250 
LEU   CG  HG   sing N N 251 
LEU   CD1 HD11 sing N N 252 
LEU   CD1 HD12 sing N N 253 
LEU   CD1 HD13 sing N N 254 
LEU   CD2 HD21 sing N N 255 
LEU   CD2 HD22 sing N N 256 
LEU   CD2 HD23 sing N N 257 
LEU   OXT HXT  sing N N 258 
LYS   N   CA   sing N N 259 
LYS   N   H    sing N N 260 
LYS   N   H2   sing N N 261 
LYS   CA  C    sing N N 262 
LYS   CA  CB   sing N N 263 
LYS   CA  HA   sing N N 264 
LYS   C   O    doub N N 265 
LYS   C   OXT  sing N N 266 
LYS   CB  CG   sing N N 267 
LYS   CB  HB2  sing N N 268 
LYS   CB  HB3  sing N N 269 
LYS   CG  CD   sing N N 270 
LYS   CG  HG2  sing N N 271 
LYS   CG  HG3  sing N N 272 
LYS   CD  CE   sing N N 273 
LYS   CD  HD2  sing N N 274 
LYS   CD  HD3  sing N N 275 
LYS   CE  NZ   sing N N 276 
LYS   CE  HE2  sing N N 277 
LYS   CE  HE3  sing N N 278 
LYS   NZ  HZ1  sing N N 279 
LYS   NZ  HZ2  sing N N 280 
LYS   NZ  HZ3  sing N N 281 
LYS   OXT HXT  sing N N 282 
MET   N   CA   sing N N 283 
MET   N   H    sing N N 284 
MET   N   H2   sing N N 285 
MET   CA  C    sing N N 286 
MET   CA  CB   sing N N 287 
MET   CA  HA   sing N N 288 
MET   C   O    doub N N 289 
MET   C   OXT  sing N N 290 
MET   CB  CG   sing N N 291 
MET   CB  HB2  sing N N 292 
MET   CB  HB3  sing N N 293 
MET   CG  SD   sing N N 294 
MET   CG  HG2  sing N N 295 
MET   CG  HG3  sing N N 296 
MET   SD  CE   sing N N 297 
MET   CE  HE1  sing N N 298 
MET   CE  HE2  sing N N 299 
MET   CE  HE3  sing N N 300 
MET   OXT HXT  sing N N 301 
PHE   N   CA   sing N N 302 
PHE   N   H    sing N N 303 
PHE   N   H2   sing N N 304 
PHE   CA  C    sing N N 305 
PHE   CA  CB   sing N N 306 
PHE   CA  HA   sing N N 307 
PHE   C   O    doub N N 308 
PHE   C   OXT  sing N N 309 
PHE   CB  CG   sing N N 310 
PHE   CB  HB2  sing N N 311 
PHE   CB  HB3  sing N N 312 
PHE   CG  CD1  doub Y N 313 
PHE   CG  CD2  sing Y N 314 
PHE   CD1 CE1  sing Y N 315 
PHE   CD1 HD1  sing N N 316 
PHE   CD2 CE2  doub Y N 317 
PHE   CD2 HD2  sing N N 318 
PHE   CE1 CZ   doub Y N 319 
PHE   CE1 HE1  sing N N 320 
PHE   CE2 CZ   sing Y N 321 
PHE   CE2 HE2  sing N N 322 
PHE   CZ  HZ   sing N N 323 
PHE   OXT HXT  sing N N 324 
PRO   N   CA   sing N N 325 
PRO   N   CD   sing N N 326 
PRO   N   H    sing N N 327 
PRO   CA  C    sing N N 328 
PRO   CA  CB   sing N N 329 
PRO   CA  HA   sing N N 330 
PRO   C   O    doub N N 331 
PRO   C   OXT  sing N N 332 
PRO   CB  CG   sing N N 333 
PRO   CB  HB2  sing N N 334 
PRO   CB  HB3  sing N N 335 
PRO   CG  CD   sing N N 336 
PRO   CG  HG2  sing N N 337 
PRO   CG  HG3  sing N N 338 
PRO   CD  HD2  sing N N 339 
PRO   CD  HD3  sing N N 340 
PRO   OXT HXT  sing N N 341 
SER   N   CA   sing N N 342 
SER   N   H    sing N N 343 
SER   N   H2   sing N N 344 
SER   CA  C    sing N N 345 
SER   CA  CB   sing N N 346 
SER   CA  HA   sing N N 347 
SER   C   O    doub N N 348 
SER   C   OXT  sing N N 349 
SER   CB  OG   sing N N 350 
SER   CB  HB2  sing N N 351 
SER   CB  HB3  sing N N 352 
SER   OG  HG   sing N N 353 
SER   OXT HXT  sing N N 354 
THR   N   CA   sing N N 355 
THR   N   H    sing N N 356 
THR   N   H2   sing N N 357 
THR   CA  C    sing N N 358 
THR   CA  CB   sing N N 359 
THR   CA  HA   sing N N 360 
THR   C   O    doub N N 361 
THR   C   OXT  sing N N 362 
THR   CB  OG1  sing N N 363 
THR   CB  CG2  sing N N 364 
THR   CB  HB   sing N N 365 
THR   OG1 HG1  sing N N 366 
THR   CG2 HG21 sing N N 367 
THR   CG2 HG22 sing N N 368 
THR   CG2 HG23 sing N N 369 
THR   OXT HXT  sing N N 370 
TRP   N   CA   sing N N 371 
TRP   N   H    sing N N 372 
TRP   N   H2   sing N N 373 
TRP   CA  C    sing N N 374 
TRP   CA  CB   sing N N 375 
TRP   CA  HA   sing N N 376 
TRP   C   O    doub N N 377 
TRP   C   OXT  sing N N 378 
TRP   CB  CG   sing N N 379 
TRP   CB  HB2  sing N N 380 
TRP   CB  HB3  sing N N 381 
TRP   CG  CD1  doub Y N 382 
TRP   CG  CD2  sing Y N 383 
TRP   CD1 NE1  sing Y N 384 
TRP   CD1 HD1  sing N N 385 
TRP   CD2 CE2  doub Y N 386 
TRP   CD2 CE3  sing Y N 387 
TRP   NE1 CE2  sing Y N 388 
TRP   NE1 HE1  sing N N 389 
TRP   CE2 CZ2  sing Y N 390 
TRP   CE3 CZ3  doub Y N 391 
TRP   CE3 HE3  sing N N 392 
TRP   CZ2 CH2  doub Y N 393 
TRP   CZ2 HZ2  sing N N 394 
TRP   CZ3 CH2  sing Y N 395 
TRP   CZ3 HZ3  sing N N 396 
TRP   CH2 HH2  sing N N 397 
TRP   OXT HXT  sing N N 398 
TYR   N   CA   sing N N 399 
TYR   N   H    sing N N 400 
TYR   N   H2   sing N N 401 
TYR   CA  C    sing N N 402 
TYR   CA  CB   sing N N 403 
TYR   CA  HA   sing N N 404 
TYR   C   O    doub N N 405 
TYR   C   OXT  sing N N 406 
TYR   CB  CG   sing N N 407 
TYR   CB  HB2  sing N N 408 
TYR   CB  HB3  sing N N 409 
TYR   CG  CD1  doub Y N 410 
TYR   CG  CD2  sing Y N 411 
TYR   CD1 CE1  sing Y N 412 
TYR   CD1 HD1  sing N N 413 
TYR   CD2 CE2  doub Y N 414 
TYR   CD2 HD2  sing N N 415 
TYR   CE1 CZ   doub Y N 416 
TYR   CE1 HE1  sing N N 417 
TYR   CE2 CZ   sing Y N 418 
TYR   CE2 HE2  sing N N 419 
TYR   CZ  OH   sing N N 420 
TYR   OH  HH   sing N N 421 
TYR   OXT HXT  sing N N 422 
VAL   N   CA   sing N N 423 
VAL   N   H    sing N N 424 
VAL   N   H2   sing N N 425 
VAL   CA  C    sing N N 426 
VAL   CA  CB   sing N N 427 
VAL   CA  HA   sing N N 428 
VAL   C   O    doub N N 429 
VAL   C   OXT  sing N N 430 
VAL   CB  CG1  sing N N 431 
VAL   CB  CG2  sing N N 432 
VAL   CB  HB   sing N N 433 
VAL   CG1 HG11 sing N N 434 
VAL   CG1 HG12 sing N N 435 
VAL   CG1 HG13 sing N N 436 
VAL   CG2 HG21 sing N N 437 
VAL   CG2 HG22 sing N N 438 
VAL   CG2 HG23 sing N N 439 
VAL   OXT HXT  sing N N 440 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           82173865 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5VAO 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9JQK 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021656 
_atom_sites.fract_transf_matrix[1][2]   -0.007129 
_atom_sites.fract_transf_matrix[1][3]   0.000543 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.019481 
_atom_sites.fract_transf_matrix[2][3]   -0.005846 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012570 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C   6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651   51.6512 0.2156   
CL  17 17 11.4601 0.0104  7.1962 1.1662  6.2554 18.5194 1.6455   47.7784 -9.3378  
H   1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408   57.7997 0.0030   
N   7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672   0.5826  -11.5379 
O   8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671   32.9089 0.2508   
O-1 8  9  4.1952  12.8573 1.6411 4.1724  1.5281 47.0179 -20.3246 -0.0140 21.9602  
S   16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863   56.1720 1.0555   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N  N   . PRO   A 1 30  ? -21.541 4.319   -10.841 1.000 61.420  0  140 PRO   D N   1 ? 
ATOM   2    C  CA  . PRO   A 1 30  ? -20.807 3.070   -11.013 1.000 64.281  0  140 PRO   D CA  1 ? 
ATOM   3    C  C   . PRO   A 1 30  ? -21.603 2.057   -11.835 1.000 58.906  0  140 PRO   D C   1 ? 
ATOM   4    O  O   . PRO   A 1 30  ? -22.784 1.832   -11.575 1.000 56.097  0  140 PRO   D O   1 ? 
ATOM   5    C  CB  . PRO   A 1 30  ? -20.547 2.590   -9.575  1.000 62.256  0  140 PRO   D CB  1 ? 
ATOM   6    C  CG  . PRO   A 1 30  ? -21.716 3.137   -8.793  1.000 60.959  0  140 PRO   D CG  1 ? 
ATOM   7    C  CD  . PRO   A 1 30  ? -22.113 4.423   -9.507  1.000 57.065  0  140 PRO   D CD  1 ? 
ATOM   8    N  N   . LYS   A 1 31  ? -20.946 1.470   -12.847 1.000 51.454  0  141 LYS   D N   1 ? 
ATOM   9    C  CA  . LYS   A 1 31  ? -21.587 0.510   -13.730 1.000 49.747  0  141 LYS   D CA  1 ? 
ATOM   10   C  C   . LYS   A 1 31  ? -21.625 -0.853  -13.043 1.000 49.378  0  141 LYS   D C   1 ? 
ATOM   11   O  O   . LYS   A 1 31  ? -20.617 -1.310  -12.505 1.000 46.891  0  141 LYS   D O   1 ? 
ATOM   12   C  CB  . LYS   A 1 31  ? -20.867 0.453   -15.083 1.000 51.988  0  141 LYS   D CB  1 ? 
ATOM   13   C  CG  . LYS   A 1 31  ? -20.973 1.730   -15.914 1.000 62.942  0  141 LYS   D CG  1 ? 
ATOM   14   C  CD  . LYS   A 1 31  ? -20.447 1.608   -17.341 1.000 74.066  0  141 LYS   D CD  1 ? 
ATOM   15   C  CE  . LYS   A 1 31  ? -18.967 1.390   -17.410 1.000 81.671  0  141 LYS   D CE  1 ? 
ATOM   16   N  NZ  . LYS   A 1 31  ? -18.502 1.307   -18.796 1.000 83.235  0  141 LYS   D NZ  1 ? 
ATOM   17   N  N   . ILE   A 1 32  ? -22.802 -1.498  -13.086 1.000 47.382  0  142 ILE   D N   1 ? 
ATOM   18   C  CA  . ILE   A 1 32  ? -23.020 -2.766  -12.406 1.000 47.727  0  142 ILE   D CA  1 ? 
ATOM   19   C  C   . ILE   A 1 32  ? -22.606 -3.906  -13.339 1.000 42.184  0  142 ILE   D C   1 ? 
ATOM   20   O  O   . ILE   A 1 32  ? -23.453 -4.629  -13.871 1.000 32.446  0  142 ILE   D O   1 ? 
ATOM   21   C  CB  . ILE   A 1 32  ? -24.488 -2.896  -11.941 1.000 49.582  0  142 ILE   D CB  1 ? 
ATOM   22   C  CG1 . ILE   A 1 32  ? -24.961 -1.640  -11.194 1.000 50.797  0  142 ILE   D CG1 1 ? 
ATOM   23   C  CG2 . ILE   A 1 32  ? -24.692 -4.163  -11.100 1.000 54.415  0  142 ILE   D CG2 1 ? 
ATOM   24   C  CD1 . ILE   A 1 32  ? -24.131 -1.292  -9.968  1.000 52.592  0  142 ILE   D CD1 1 ? 
ATOM   25   N  N   . THR   A 1 33  ? -21.290 -4.058  -13.520 1.000 41.012  0  143 THR   D N   1 ? 
ATOM   26   C  CA  . THR   A 1 33  ? -20.738 -5.156  -14.295 1.000 39.952  0  143 THR   D CA  1 ? 
ATOM   27   C  C   . THR   A 1 33  ? -20.799 -6.431  -13.458 1.000 42.891  0  143 THR   D C   1 ? 
ATOM   28   O  O   . THR   A 1 33  ? -21.120 -6.387  -12.271 1.000 38.596  0  143 THR   D O   1 ? 
ATOM   29   C  CB  . THR   A 1 33  ? -19.304 -4.823  -14.713 1.000 42.681  0  143 THR   D CB  1 ? 
ATOM   30   O  OG1 . THR   A 1 33  ? -18.595 -4.555  -13.504 1.000 35.325  0  143 THR   D OG1 1 ? 
ATOM   31   C  CG2 . THR   A 1 33  ? -19.230 -3.623  -15.641 1.000 42.365  0  143 THR   D CG2 1 ? 
ATOM   32   N  N   . LEU   A 1 34  ? -20.476 -7.561  -14.094 1.000 44.534  0  144 LEU   D N   1 ? 
ATOM   33   C  CA  . LEU   A 1 34  ? -20.401 -8.846  -13.415 1.000 42.097  0  144 LEU   D CA  1 ? 
ATOM   34   C  C   . LEU   A 1 34  ? -19.367 -8.765  -12.287 1.000 39.999  0  144 LEU   D C   1 ? 
ATOM   35   O  O   . LEU   A 1 34  ? -19.629 -9.196  -11.165 1.000 36.446  0  144 LEU   D O   1 ? 
ATOM   36   C  CB  . LEU   A 1 34  ? -20.035 -9.925  -14.434 1.000 53.095  0  144 LEU   D CB  1 ? 
ATOM   37   C  CG  . LEU   A 1 34  ? -21.034 -10.140 -15.576 1.000 68.840  0  144 LEU   D CG  1 ? 
ATOM   38   C  CD1 . LEU   A 1 34  ? -20.355 -10.760 -16.789 1.000 78.625  0  144 LEU   D CD1 1 ? 
ATOM   39   C  CD2 . LEU   A 1 34  ? -22.194 -11.003 -15.117 1.000 75.639  0  144 LEU   D CD2 1 ? 
ATOM   40   N  N   . LEU   A 1 35  ? -18.212 -8.155  -12.595 1.000 34.310  0  145 LEU   D N   1 ? 
ATOM   41   C  CA  . LEU   A 1 35  ? -17.108 -8.043  -11.653 1.000 34.162  0  145 LEU   D CA  1 ? 
ATOM   42   C  C   . LEU   A 1 35  ? -17.515 -7.167  -10.461 1.000 37.490  0  145 LEU   D C   1 ? 
ATOM   43   O  O   . LEU   A 1 35  ? -17.207 -7.497  -9.320  1.000 35.825  0  145 LEU   D O   1 ? 
ATOM   44   C  CB  . LEU   A 1 35  ? -15.887 -7.483  -12.383 1.000 30.605  0  145 LEU   D CB  1 ? 
ATOM   45   C  CG  . LEU   A 1 35  ? -14.616 -7.311  -11.546 1.000 36.079  0  145 LEU   D CG  1 ? 
ATOM   46   C  CD1 . LEU   A 1 35  ? -14.190 -8.617  -10.900 1.000 40.288  0  145 LEU   D CD1 1 ? 
ATOM   47   C  CD2 . LEU   A 1 35  ? -13.493 -6.753  -12.403 1.000 39.845  0  145 LEU   D CD2 1 ? 
ATOM   48   N  N   . THR   A 1 36  ? -18.196 -6.043  -10.742 1.000 35.864  0  146 THR   D N   1 ? 
ATOM   49   C  CA  . THR   A 1 36  ? -18.664 -5.139  -9.696  1.000 38.505  0  146 THR   D CA  1 ? 
ATOM   50   C  C   . THR   A 1 36  ? -19.663 -5.870  -8.795  1.000 39.454  0  146 THR   D C   1 ? 
ATOM   51   O  O   . THR   A 1 36  ? -19.723 -5.617  -7.589  1.000 36.717  0  146 THR   D O   1 ? 
ATOM   52   C  CB  . THR   A 1 36  ? -19.286 -3.888  -10.325 1.000 40.206  0  146 THR   D CB  1 ? 
ATOM   53   O  OG1 . THR   A 1 36  ? -18.201 -3.157  -10.887 1.000 44.934  0  146 THR   D OG1 1 ? 
ATOM   54   C  CG2 . THR   A 1 36  ? -19.990 -3.006  -9.310  1.000 37.360  0  146 THR   D CG2 1 ? 
ATOM   55   N  N   . LEU   A 1 37  ? -20.460 -6.756  -9.396  1.000 30.936  0  147 LEU   D N   1 ? 
ATOM   56   C  CA  . LEU   A 1 37  ? -21.457 -7.514  -8.662  1.000 36.612  0  147 LEU   D CA  1 ? 
ATOM   57   C  C   . LEU   A 1 37  ? -20.753 -8.470  -7.688  1.000 40.254  0  147 LEU   D C   1 ? 
ATOM   58   O  O   . LEU   A 1 37  ? -21.161 -8.595  -6.535  1.000 39.995  0  147 LEU   D O   1 ? 
ATOM   59   C  CB  . LEU   A 1 37  ? -22.347 -8.262  -9.654  1.000 42.070  0  147 LEU   D CB  1 ? 
ATOM   60   C  CG  . LEU   A 1 37  ? -23.749 -8.618  -9.166  1.000 48.048  0  147 LEU   D CG  1 ? 
ATOM   61   C  CD1 . LEU   A 1 37  ? -24.625 -7.375  -9.065  1.000 45.384  0  147 LEU   D CD1 1 ? 
ATOM   62   C  CD2 . LEU   A 1 37  ? -24.378 -9.648  -10.077 1.000 55.342  0  147 LEU   D CD2 1 ? 
ATOM   63   N  N   . ILE   A 1 38  ? -19.676 -9.120  -8.167  1.000 42.301  0  148 ILE   D N   1 ? 
ATOM   64   C  CA  . ILE   A 1 38  ? -18.895 -10.049 -7.356  1.000 39.042  0  148 ILE   D CA  1 ? 
ATOM   65   C  C   . ILE   A 1 38  ? -18.227 -9.285  -6.209  1.000 37.176  0  148 ILE   D C   1 ? 
ATOM   66   O  O   . ILE   A 1 38  ? -18.305 -9.703  -5.053  1.000 36.058  0  148 ILE   D O   1 ? 
ATOM   67   C  CB  . ILE   A 1 38  ? -17.860 -10.797 -8.222  1.000 38.224  0  148 ILE   D CB  1 ? 
ATOM   68   C  CG1 . ILE   A 1 38  ? -18.535 -11.792 -9.165  1.000 43.334  0  148 ILE   D CG1 1 ? 
ATOM   69   C  CG2 . ILE   A 1 38  ? -16.804 -11.481 -7.349  1.000 42.715  0  148 ILE   D CG2 1 ? 
ATOM   70   C  CD1 . ILE   A 1 38  ? -17.596 -12.421 -10.180 1.000 48.242  0  148 ILE   D CD1 1 ? 
ATOM   71   N  N   . LYS   A 1 39  ? -17.538 -8.189  -6.553  1.000 33.843  0  149 LYS   D N   1 ? 
ATOM   72   C  CA  . LYS   A 1 39  ? -16.828 -7.369  -5.578  1.000 36.220  0  149 LYS   D CA  1 ? 
ATOM   73   C  C   . LYS   A 1 39  ? -17.779 -6.924  -4.467  1.000 32.843  0  149 LYS   D C   1 ? 
ATOM   74   O  O   . LYS   A 1 39  ? -17.384 -6.841  -3.310  1.000 36.813  0  149 LYS   D O   1 ? 
ATOM   75   C  CB  . LYS   A 1 39  ? -16.208 -6.139  -6.250  1.000 39.821  0  149 LYS   D CB  1 ? 
ATOM   76   C  CG  . LYS   A 1 39  ? -14.909 -6.379  -7.004  1.000 39.895  0  149 LYS   D CG  1 ? 
ATOM   77   C  CD  . LYS   A 1 39  ? -14.472 -5.168  -7.826  1.000 45.927  0  149 LYS   D CD  1 ? 
ATOM   78   C  CE  . LYS   A 1 39  ? -12.987 -5.088  -8.041  1.000 55.934  0  149 LYS   D CE  1 ? 
ATOM   79   N  NZ  . LYS   A 1 39  ? -12.444 -6.283  -8.692  1.000 69.654  0  149 LYS   D NZ  1 ? 
ATOM   80   N  N   . THR   A 1 40  ? -19.018 -6.595  -4.846  1.000 33.920  0  150 THR   D N   1 ? 
ATOM   81   C  CA  . THR   A 1 40  ? -20.025 -6.143  -3.897  1.000 36.180  0  150 THR   D CA  1 ? 
ATOM   82   C  C   . THR   A 1 40  ? -20.380 -7.288  -2.944  1.000 37.271  0  150 THR   D C   1 ? 
ATOM   83   O  O   . THR   A 1 40  ? -20.497 -7.077  -1.736  1.000 33.122  0  150 THR   D O   1 ? 
ATOM   84   C  CB  . THR   A 1 40  ? -21.246 -5.631  -4.662  1.000 35.144  0  150 THR   D CB  1 ? 
ATOM   85   O  OG1 . THR   A 1 40  ? -20.755 -4.539  -5.433  1.000 33.054  0  150 THR   D OG1 1 ? 
ATOM   86   C  CG2 . THR   A 1 40  ? -22.365 -5.161  -3.749  1.000 33.592  0  150 THR   D CG2 1 ? 
ATOM   87   N  N   . ALA   A 1 41  ? -20.542 -8.499  -3.499  1.000 34.046  0  151 ALA   D N   1 ? 
ATOM   88   C  CA  . ALA   A 1 41  ? -20.874 -9.673  -2.701  1.000 35.477  0  151 ALA   D CA  1 ? 
ATOM   89   C  C   . ALA   A 1 41  ? -19.730 -9.997  -1.735  1.000 31.903  0  151 ALA   D C   1 ? 
ATOM   90   O  O   . ALA   A 1 41  ? -19.975 -10.322 -0.582  1.000 37.033  0  151 ALA   D O   1 ? 
ATOM   91   C  CB  . ALA   A 1 41  ? -21.187 -10.843 -3.602  1.000 33.312  0  151 ALA   D CB  1 ? 
ATOM   92   N  N   . GLU   A 1 42  ? -18.483 -9.906  -2.226  1.000 34.653  0  152 GLU   D N   1 ? 
ATOM   93   C  CA  . GLU   A 1 42  ? -17.300 -10.152 -1.400  1.000 40.125  0  152 GLU   D CA  1 ? 
ATOM   94   C  C   . GLU   A 1 42  ? -17.330 -9.250  -0.170  1.000 38.106  0  152 GLU   D C   1 ? 
ATOM   95   O  O   . GLU   A 1 42  ? -17.134 -9.721  0.948   1.000 40.965  0  152 GLU   D O   1 ? 
ATOM   96   C  CB  . GLU   A 1 42  ? -16.004 -9.926  -2.180  1.000 41.437  0  152 GLU   D CB  1 ? 
ATOM   97   C  CG  . GLU   A 1 42  ? -15.623 -11.099 -3.080  1.000 48.556  0  152 GLU   D CG  1 ? 
ATOM   98   C  CD  . GLU   A 1 42  ? -14.444 -10.833 -4.009  1.000 53.357  0  152 GLU   D CD  1 ? 
ATOM   99   O  OE1 . GLU   A 1 42  ? -13.901 -9.704  -3.990  1.000 57.643  0  152 GLU   D OE1 1 ? 
ATOM   100  O  OE2 . GLU   A 1 42  ? -14.084 -11.753 -4.772  1.000 55.184  0  152 GLU   D OE2 1 ? 
ATOM   101  N  N   . HIS   A 1 43  ? -17.616 -7.959  -0.391  1.000 34.371  0  153 HIS   D N   1 ? 
ATOM   102  C  CA  . HIS   A 1 43  ? -17.610 -6.973  0.676   1.000 32.859  0  153 HIS   D CA  1 ? 
ATOM   103  C  C   . HIS   A 1 43  ? -18.690 -7.296  1.711   1.000 33.242  0  153 HIS   D C   1 ? 
ATOM   104  O  O   . HIS   A 1 43  ? -18.405 -7.345  2.902   1.000 33.953  0  153 HIS   D O   1 ? 
ATOM   105  C  CB  . HIS   A 1 43  ? -17.769 -5.555  0.114   1.000 36.939  0  153 HIS   D CB  1 ? 
ATOM   106  C  CG  . HIS   A 1 43  ? -17.714 -4.489  1.164   1.000 40.658  0  153 HIS   D CG  1 ? 
ATOM   107  N  ND1 . HIS   A 1 43  ? -16.556 -4.186  1.849   1.000 41.571  0  153 HIS   D ND1 1 ? 
ATOM   108  C  CD2 . HIS   A 1 43  ? -18.684 -3.750  1.734   1.000 41.689  0  153 HIS   D CD2 1 ? 
ATOM   109  C  CE1 . HIS   A 1 43  ? -16.813 -3.244  2.749   1.000 43.766  0  153 HIS   D CE1 1 ? 
ATOM   110  N  NE2 . HIS   A 1 43  ? -18.096 -2.956  2.690   1.000 40.015  0  153 HIS   D NE2 1 ? 
ATOM   111  N  N   . TRP   A 1 44  ? -19.926 -7.524  1.245   1.000 28.234  0  154 TRP   D N   1 ? 
ATOM   112  C  CA  . TRP   A 1 44  ? -21.065 -7.672  2.145   1.000 29.435  0  154 TRP   D CA  1 ? 
ATOM   113  C  C   . TRP   A 1 44  ? -21.105 -9.066  2.775   1.000 31.387  0  154 TRP   D C   1 ? 
ATOM   114  O  O   . TRP   A 1 44  ? -21.759 -9.256  3.796   1.000 31.653  0  154 TRP   D O   1 ? 
ATOM   115  C  CB  . TRP   A 1 44  ? -22.371 -7.340  1.417   1.000 32.198  0  154 TRP   D CB  1 ? 
ATOM   116  C  CG  . TRP   A 1 44  ? -22.540 -5.865  1.185   1.000 32.049  0  154 TRP   D CG  1 ? 
ATOM   117  C  CD1 . TRP   A 1 44  ? -22.259 -5.173  0.047   1.000 31.191  0  154 TRP   D CD1 1 ? 
ATOM   118  C  CD2 . TRP   A 1 44  ? -22.855 -4.877  2.187   1.000 33.951  0  154 TRP   D CD2 1 ? 
ATOM   119  N  NE1 . TRP   A 1 44  ? -22.448 -3.834  0.248   1.000 36.352  0  154 TRP   D NE1 1 ? 
ATOM   120  C  CE2 . TRP   A 1 44  ? -22.797 -3.620  1.554   1.000 32.878  0  154 TRP   D CE2 1 ? 
ATOM   121  C  CE3 . TRP   A 1 44  ? -23.190 -4.935  3.545   1.000 35.083  0  154 TRP   D CE3 1 ? 
ATOM   122  C  CZ2 . TRP   A 1 44  ? -23.066 -2.434  2.233   1.000 36.461  0  154 TRP   D CZ2 1 ? 
ATOM   123  C  CZ3 . TRP   A 1 44  ? -23.454 -3.760  4.215   1.000 35.099  0  154 TRP   D CZ3 1 ? 
ATOM   124  C  CH2 . TRP   A 1 44  ? -23.374 -2.526  3.571   1.000 34.538  0  154 TRP   D CH2 1 ? 
ATOM   125  N  N   . ALA   A 1 45  ? -20.343 -10.012 2.208   1.000 33.707  0  155 ALA   D N   1 ? 
ATOM   126  C  CA  . ALA   A 1 45  ? -20.258 -11.356 2.765   1.000 37.387  0  155 ALA   D CA  1 ? 
ATOM   127  C  C   . ALA   A 1 45  ? -19.545 -11.332 4.124   1.000 39.664  0  155 ALA   D C   1 ? 
ATOM   128  O  O   . ALA   A 1 45  ? -19.804 -12.186 4.965   1.000 38.949  0  155 ALA   D O   1 ? 
ATOM   129  C  CB  . ALA   A 1 45  ? -19.554 -12.276 1.796   1.000 41.648  0  155 ALA   D CB  1 ? 
ATOM   130  N  N   . ARG   A 1 46  ? -18.659 -10.333 4.331   1.000 36.517  0  156 ARG   D N   1 ? 
ATOM   131  C  CA  . ARG   A 1 46  ? -17.817 -10.278 5.523   1.000 41.895  0  156 ARG   D CA  1 ? 
ATOM   132  C  C   . ARG   A 1 46  ? -18.283 -9.160  6.474   1.000 40.793  0  156 ARG   D C   1 ? 
ATOM   133  O  O   . ARG   A 1 46  ? -17.566 -8.808  7.414   1.000 41.216  0  156 ARG   D O   1 ? 
ATOM   134  C  CB  . ARG   A 1 46  ? -16.349 -10.055 5.123   1.000 47.940  0  156 ARG   D CB  1 ? 
ATOM   135  C  CG  . ARG   A 1 46  ? -16.019 -8.635  4.677   1.000 52.763  0  156 ARG   D CG  1 ? 
ATOM   136  C  CD  . ARG   A 1 46  ? -14.567 -8.457  4.270   1.000 64.636  0  156 ARG   D CD  1 ? 
ATOM   137  N  NE  . ARG   A 1 46  ? -14.259 -7.039  4.031   1.000 77.995  0  156 ARG   D NE  1 ? 
ATOM   138  C  CZ  . ARG   A 1 46  ? -14.008 -6.480  2.840   1.000 78.726  0  156 ARG   D CZ  1 ? 
ATOM   139  N  NH1 . ARG   A 1 46  ? -14.032 -7.211  1.735   1.000 73.217  0  156 ARG   D NH1 1 ? 
ATOM   140  N  NH2 . ARG   A 1 46  ? -13.750 -5.183  2.761   1.000 80.848  0  156 ARG   D NH2 1 ? 
ATOM   141  N  N   . GLN   A 1 47  ? -19.490 -8.623  6.239   1.000 40.248  0  157 GLN   D N   1 ? 
ATOM   142  C  CA  . GLN   A 1 47  ? -20.019 -7.538  7.056   1.000 39.653  0  157 GLN   D CA  1 ? 
ATOM   143  C  C   . GLN   A 1 47  ? -21.006 -8.086  8.083   1.000 38.507  0  157 GLN   D C   1 ? 
ATOM   144  O  O   . GLN   A 1 47  ? -21.716 -9.053  7.818   1.000 38.516  0  157 GLN   D O   1 ? 
ATOM   145  C  CB  . GLN   A 1 47  ? -20.727 -6.486  6.200   1.000 40.628  0  157 GLN   D CB  1 ? 
ATOM   146  C  CG  . GLN   A 1 47  ? -19.802 -5.698  5.282   1.000 44.034  0  157 GLN   D CG  1 ? 
ATOM   147  C  CD  . GLN   A 1 47  ? -18.781 -4.869  6.032   1.000 44.925  0  157 GLN   D CD  1 ? 
ATOM   148  O  OE1 . GLN   A 1 47  ? -19.121 -4.063  6.905   1.000 50.364  0  157 GLN   D OE1 1 ? 
ATOM   149  N  NE2 . GLN   A 1 47  ? -17.512 -5.061  5.700   1.000 54.155  0  157 GLN   D NE2 1 ? 
ATOM   150  N  N   . ASP   A 1 48  ? -21.022 -7.452  9.264   1.000 46.628  0  158 ASP   D N   1 ? 
ATOM   151  C  CA  . ASP   A 1 48  ? -22.056 -7.669  10.263  1.000 46.756  0  158 ASP   D CA  1 ? 
ATOM   152  C  C   . ASP   A 1 48  ? -23.267 -6.820  9.877   1.000 43.453  0  158 ASP   D C   1 ? 
ATOM   153  O  O   . ASP   A 1 48  ? -23.238 -5.600  10.023  1.000 50.122  0  158 ASP   D O   1 ? 
ATOM   154  C  CB  . ASP   A 1 48  ? -21.547 -7.320  11.659  1.000 44.889  0  158 ASP   D CB  1 ? 
ATOM   155  C  CG  . ASP   A 1 48  ? -22.522 -7.554  12.808  1.000 46.275  0  158 ASP   D CG  1 ? 
ATOM   156  O  OD1 . ASP   A 1 48  ? -23.641 -8.032  12.543  1.000 46.709  0  158 ASP   D OD1 1 ? 
ATOM   157  O  OD2 . ASP   A 1 48  ? -22.151 -7.254  13.960  1.000 55.274  0  158 ASP   D OD2 1 ? 
ATOM   158  N  N   . ILE   A 1 49  ? -24.322 -7.481  9.382   1.000 41.888  0  159 ILE   D N   1 ? 
ATOM   159  C  CA  . ILE   A 1 49  ? -25.470 -6.787  8.811   1.000 45.101  0  159 ILE   D CA  1 ? 
ATOM   160  C  C   . ILE   A 1 49  ? -26.677 -6.929  9.744   1.000 46.715  0  159 ILE   D C   1 ? 
ATOM   161  O  O   . ILE   A 1 49  ? -27.813 -6.726  9.321   1.000 51.385  0  159 ILE   D O   1 ? 
ATOM   162  C  CB  . ILE   A 1 49  ? -25.777 -7.318  7.393   1.000 43.201  0  159 ILE   D CB  1 ? 
ATOM   163  C  CG1 . ILE   A 1 49  ? -26.252 -8.784  7.417   1.000 44.141  0  159 ILE   D CG1 1 ? 
ATOM   164  C  CG2 . ILE   A 1 49  ? -24.570 -7.130  6.470   1.000 45.585  0  159 ILE   D CG2 1 ? 
ATOM   165  C  CD1 . ILE   A 1 49  ? -26.805 -9.280  6.091   1.000 45.725  0  159 ILE   D CD1 1 ? 
ATOM   166  N  N   . ARG   A 1 50  ? -26.413 -7.189  11.033  1.000 50.393  0  160 ARG   D N   1 ? 
ATOM   167  C  CA  . ARG   A 1 50  ? -27.472 -7.470  11.994  1.000 54.942  0  160 ARG   D CA  1 ? 
ATOM   168  C  C   . ARG   A 1 50  ? -28.204 -6.184  12.390  1.000 56.499  0  160 ARG   D C   1 ? 
ATOM   169  O  O   . ARG   A 1 50  ? -29.286 -6.252  12.969  1.000 53.332  0  160 ARG   D O   1 ? 
ATOM   170  C  CB  . ARG   A 1 50  ? -26.918 -8.170  13.239  1.000 53.523  0  160 ARG   D CB  1 ? 
ATOM   171  C  CG  . ARG   A 1 50  ? -26.484 -9.609  13.004  1.000 55.149  0  160 ARG   D CG  1 ? 
ATOM   172  C  CD  . ARG   A 1 50  ? -25.992 -10.273 14.284  1.000 56.516  0  160 ARG   D CD  1 ? 
ATOM   173  N  NE  . ARG   A 1 50  ? -24.770 -9.644  14.800  1.000 60.902  0  160 ARG   D NE  1 ? 
ATOM   174  C  CZ  . ARG   A 1 50  ? -24.141 -9.990  15.924  1.000 58.507  0  160 ARG   D CZ  1 ? 
ATOM   175  N  NH1 . ARG   A 1 50  ? -24.635 -10.940 16.703  1.000 61.235  0  160 ARG   D NH1 1 ? 
ATOM   176  N  NH2 . ARG   A 1 50  ? -23.026 -9.365  16.275  1.000 52.035  0  160 ARG   D NH2 1 ? 
ATOM   177  N  N   . THR   A 1 51  ? -27.603 -5.016  12.091  1.000 57.341  0  161 THR   D N   1 ? 
ATOM   178  C  CA  . THR   A 1 51  ? -28.166 -3.740  12.517  1.000 54.764  0  161 THR   D CA  1 ? 
ATOM   179  C  C   . THR   A 1 51  ? -28.047 -2.696  11.399  1.000 61.886  0  161 THR   D C   1 ? 
ATOM   180  O  O   . THR   A 1 51  ? -27.920 -1.506  11.681  1.000 72.578  0  161 THR   D O   1 ? 
ATOM   181  C  CB  . THR   A 1 51  ? -27.451 -3.274  13.791  1.000 60.329  0  161 THR   D CB  1 ? 
ATOM   182  O  OG1 . THR   A 1 51  ? -26.093 -3.066  13.417  1.000 59.183  0  161 THR   D OG1 1 ? 
ATOM   183  C  CG2 . THR   A 1 51  ? -27.538 -4.286  14.922  1.000 57.076  0  161 THR   D CG2 1 ? 
ATOM   184  N  N   . ILE   A 1 52  ? -28.134 -3.139  10.131  1.000 73.214  0  162 ILE   D N   1 ? 
ATOM   185  C  CA  . ILE   A 1 52  ? -28.134 -2.211  9.000   1.000 67.031  0  162 ILE   D CA  1 ? 
ATOM   186  C  C   . ILE   A 1 52  ? -29.550 -1.674  8.801   1.000 56.251  0  162 ILE   D C   1 ? 
ATOM   187  O  O   . ILE   A 1 52  ? -30.503 -2.193  9.375   1.000 54.273  0  162 ILE   D O   1 ? 
ATOM   188  C  CB  . ILE   A 1 52  ? -27.597 -2.869  7.709   1.000 66.789  0  162 ILE   D CB  1 ? 
ATOM   189  C  CG1 . ILE   A 1 52  ? -28.473 -4.047  7.256   1.000 66.644  0  162 ILE   D CG1 1 ? 
ATOM   190  C  CG2 . ILE   A 1 52  ? -26.133 -3.277  7.875   1.000 70.512  0  162 ILE   D CG2 1 ? 
ATOM   191  C  CD1 . ILE   A 1 52  ? -28.356 -4.372  5.777   1.000 71.576  0  162 ILE   D CD1 1 ? 
ATOM   192  N  N   . GLU   A 1 53  ? -29.671 -0.652  7.949   1.000 55.335  0  163 GLU   D N   1 ? 
ATOM   193  C  CA  . GLU   A 1 53  ? -30.966 -0.096  7.586   1.000 64.312  0  163 GLU   D CA  1 ? 
ATOM   194  C  C   . GLU   A 1 53  ? -31.720 -1.101  6.711   1.000 55.676  0  163 GLU   D C   1 ? 
ATOM   195  O  O   . GLU   A 1 53  ? -31.112 -1.977  6.096   1.000 56.750  0  163 GLU   D O   1 ? 
ATOM   196  C  CB  . GLU   A 1 53  ? -30.787 1.236   6.854   1.000 78.846  0  163 GLU   D CB  1 ? 
ATOM   197  C  CG  . GLU   A 1 53  ? -30.118 2.314   7.706   1.000 94.151  0  163 GLU   D CG  1 ? 
ATOM   198  C  CD  . GLU   A 1 53  ? -29.864 3.627   6.982   1.000 104.763 0  163 GLU   D CD  1 ? 
ATOM   199  O  OE1 . GLU   A 1 53  ? -30.231 3.738   5.792   1.000 97.853  0  163 GLU   D OE1 1 ? 
ATOM   200  O  OE2 . GLU   A 1 53  ? -29.284 4.539   7.611   1.000 129.837 0  163 GLU   D OE2 1 ? 
ATOM   201  N  N   . ASP   A 1 54  ? -33.051 -0.957  6.669   1.000 60.622  0  164 ASP   D N   1 ? 
ATOM   202  C  CA  . ASP   A 1 54  ? -33.907 -1.832  5.877   1.000 62.540  0  164 ASP   D CA  1 ? 
ATOM   203  C  C   . ASP   A 1 54  ? -33.726 -1.525  4.390   1.000 52.060  0  164 ASP   D C   1 ? 
ATOM   204  O  O   . ASP   A 1 54  ? -33.932 -2.396  3.549   1.000 65.129  0  164 ASP   D O   1 ? 
ATOM   205  C  CB  . ASP   A 1 54  ? -35.366 -1.716  6.298   1.000 67.888  0  164 ASP   D CB  1 ? 
ATOM   206  C  CG  . ASP   A 1 54  ? -35.720 -2.354  7.635   1.000 80.456  0  164 ASP   D CG  1 ? 
ATOM   207  O  OD1 . ASP   A 1 54  ? -34.811 -2.935  8.272   1.000 98.186  0  164 ASP   D OD1 1 ? 
ATOM   208  O  OD2 . ASP   A 1 54  ? -36.907 -2.288  8.017   1.000 99.392  0  164 ASP   D OD2 1 ? 
ATOM   209  N  N   . SER   A 1 55  ? -33.370 -0.271  4.080   1.000 44.880  0  165 SER   D N   1 ? 
ATOM   210  C  CA  . SER   A 1 55  ? -33.129 0.147   2.707   1.000 49.284  0  165 SER   D CA  1 ? 
ATOM   211  C  C   . SER   A 1 55  ? -31.977 -0.663  2.108   1.000 47.155  0  165 SER   D C   1 ? 
ATOM   212  O  O   . SER   A 1 55  ? -32.066 -1.125  0.972   1.000 44.271  0  165 SER   D O   1 ? 
ATOM   213  C  CB  . SER   A 1 55  ? -32.850 1.629   2.628   1.000 48.352  0  165 SER   D CB  1 ? 
ATOM   214  O  OG  . SER   A 1 55  ? -31.654 1.963   3.318   1.000 52.444  0  165 SER   D OG  1 ? 
ATOM   215  N  N   . LYS   A 1 56  ? -30.897 -0.820  2.887   1.000 44.861  0  166 LYS   D N   1 ? 
ATOM   216  C  CA  . LYS   A 1 56  ? -29.721 -1.558  2.444   1.000 48.598  0  166 LYS   D CA  1 ? 
ATOM   217  C  C   . LYS   A 1 56  ? -29.994 -3.061  2.501   1.000 41.717  0  166 LYS   D C   1 ? 
ATOM   218  O  O   . LYS   A 1 56  ? -29.489 -3.813  1.670   1.000 40.629  0  166 LYS   D O   1 ? 
ATOM   219  C  CB  . LYS   A 1 56  ? -28.483 -1.176  3.267   1.000 51.321  0  166 LYS   D CB  1 ? 
ATOM   220  C  CG  . LYS   A 1 56  ? -27.797 0.109   2.814   1.000 60.120  0  166 LYS   D CG  1 ? 
ATOM   221  C  CD  . LYS   A 1 56  ? -26.575 0.489   3.638   1.000 64.100  0  166 LYS   D CD  1 ? 
ATOM   222  C  CE  . LYS   A 1 56  ? -25.844 1.659   3.064   1.000 69.807  0  166 LYS   D CE  1 ? 
ATOM   223  N  NZ  . LYS   A 1 56  ? -24.711 2.055   3.905   1.000 79.069  0  166 LYS   D NZ  1 ? 
ATOM   224  N  N   . LEU   A 1 57  ? -30.791 -3.491  3.487   1.000 35.797  0  167 LEU   D N   1 ? 
ATOM   225  C  CA  . LEU   A 1 57  ? -31.137 -4.895  3.621   1.000 38.308  0  167 LEU   D CA  1 ? 
ATOM   226  C  C   . LEU   A 1 57  ? -31.977 -5.329  2.416   1.000 39.167  0  167 LEU   D C   1 ? 
ATOM   227  O  O   . LEU   A 1 57  ? -31.843 -6.455  1.941   1.000 40.233  0  167 LEU   D O   1 ? 
ATOM   228  C  CB  . LEU   A 1 57  ? -31.872 -5.156  4.933   1.000 39.798  0  167 LEU   D CB  1 ? 
ATOM   229  C  CG  . LEU   A 1 57  ? -32.237 -6.621  5.205   1.000 45.337  0  167 LEU   D CG  1 ? 
ATOM   230  C  CD1 . LEU   A 1 57  ? -30.985 -7.481  5.307   1.000 49.731  0  167 LEU   D CD1 1 ? 
ATOM   231  C  CD2 . LEU   A 1 57  ? -33.086 -6.767  6.451   1.000 44.681  0  167 LEU   D CD2 1 ? 
ATOM   232  N  N   . ARG   A 1 58  ? -32.852 -4.427  1.943   1.000 41.299  0  168 ARG   D N   1 ? 
ATOM   233  C  CA  . ARG   A 1 58  ? -33.714 -4.703  0.798   1.000 45.486  0  168 ARG   D CA  1 ? 
ATOM   234  C  C   . ARG   A 1 58  ? -32.864 -4.831  -0.468  1.000 39.883  0  168 ARG   D C   1 ? 
ATOM   235  O  O   . ARG   A 1 58  ? -33.139 -5.677  -1.315  1.000 35.748  0  168 ARG   D O   1 ? 
ATOM   236  C  CB  . ARG   A 1 58  ? -34.761 -3.592  0.627   1.000 45.890  0  168 ARG   D CB  1 ? 
ATOM   237  C  CG  . ARG   A 1 58  ? -35.754 -3.819  -0.507  1.000 42.664  0  168 ARG   D CG  1 ? 
ATOM   238  C  CD  . ARG   A 1 58  ? -36.752 -4.912  -0.186  1.000 43.999  0  168 ARG   D CD  1 ? 
ATOM   239  N  NE  . ARG   A 1 58  ? -37.575 -5.290  -1.343  1.000 44.028  0  168 ARG   D NE  1 ? 
ATOM   240  C  CZ  . ARG   A 1 58  ? -37.151 -5.984  -2.403  1.000 43.378  0  168 ARG   D CZ  1 ? 
ATOM   241  N  NH1 . ARG   A 1 58  ? -35.896 -6.408  -2.475  1.000 48.209  0  168 ARG   D NH1 1 ? 
ATOM   242  N  NH2 . ARG   A 1 58  ? -37.990 -6.260  -3.385  1.000 43.686  0  168 ARG   D NH2 1 ? 
ATOM   243  N  N   . ALA   A 1 59  ? -31.864 -3.944  -0.603  1.000 37.650  0  169 ALA   D N   1 ? 
ATOM   244  C  CA  . ALA   A 1 59  ? -30.957 -3.961  -1.743  1.000 36.769  0  169 ALA   D CA  1 ? 
ATOM   245  C  C   . ALA   A 1 59  ? -30.128 -5.251  -1.742  1.000 35.547  0  169 ALA   D C   1 ? 
ATOM   246  O  O   . ALA   A 1 59  ? -29.884 -5.835  -2.797  1.000 31.594  0  169 ALA   D O   1 ? 
ATOM   247  C  CB  . ALA   A 1 59  ? -30.071 -2.733  -1.715  1.000 37.160  0  169 ALA   D CB  1 ? 
ATOM   248  N  N   . LEU   A 1 60  ? -29.697 -5.681  -0.545  1.000 32.743  0  170 LEU   D N   1 ? 
ATOM   249  C  CA  . LEU   A 1 60  ? -28.918 -6.907  -0.395  1.000 35.749  0  170 LEU   D CA  1 ? 
ATOM   250  C  C   . LEU   A 1 60  ? -29.731 -8.109  -0.877  1.000 34.565  0  170 LEU   D C   1 ? 
ATOM   251  O  O   . LEU   A 1 60  ? -29.164 -9.077  -1.384  1.000 33.038  0  170 LEU   D O   1 ? 
ATOM   252  C  CB  . LEU   A 1 60  ? -28.464 -7.088  1.055   1.000 35.329  0  170 LEU   D CB  1 ? 
ATOM   253  C  CG  . LEU   A 1 60  ? -27.228 -6.287  1.482   1.000 34.739  0  170 LEU   D CG  1 ? 
ATOM   254  C  CD1 . LEU   A 1 60  ? -27.029 -6.370  2.981   1.000 35.375  0  170 LEU   D CD1 1 ? 
ATOM   255  C  CD2 . LEU   A 1 60  ? -25.983 -6.772  0.759   1.000 34.977  0  170 LEU   D CD2 1 ? 
ATOM   256  N  N   . LEU   A 1 61  ? -31.058 -8.056  -0.686  1.000 35.494  0  171 LEU   D N   1 ? 
ATOM   257  C  CA  . LEU   A 1 61  ? -31.932 -9.132  -1.132  1.000 37.777  0  171 LEU   D CA  1 ? 
ATOM   258  C  C   . LEU   A 1 61  ? -31.979 -9.142  -2.660  1.000 35.470  0  171 LEU   D C   1 ? 
ATOM   259  O  O   . LEU   A 1 61  ? -32.017 -10.209 -3.273  1.000 38.158  0  171 LEU   D O   1 ? 
ATOM   260  C  CB  . LEU   A 1 61  ? -33.329 -8.995  -0.528  1.000 36.504  0  171 LEU   D CB  1 ? 
ATOM   261  C  CG  . LEU   A 1 61  ? -34.285 -10.164 -0.794  1.000 41.059  0  171 LEU   D CG  1 ? 
ATOM   262  C  CD1 . LEU   A 1 61  ? -33.722 -11.471 -0.243  1.000 42.741  0  171 LEU   D CD1 1 ? 
ATOM   263  C  CD2 . LEU   A 1 61  ? -35.656 -9.887  -0.210  1.000 45.157  0  171 LEU   D CD2 1 ? 
ATOM   264  N  N   . THR   A 1 62  ? -31.988 -7.939  -3.261  1.000 34.191  0  172 THR   D N   1 ? 
ATOM   265  C  CA  . THR   A 1 62  ? -31.928 -7.791  -4.711  1.000 34.227  0  172 THR   D CA  1 ? 
ATOM   266  C  C   . THR   A 1 62  ? -30.612 -8.379  -5.223  1.000 33.951  0  172 THR   D C   1 ? 
ATOM   267  O  O   . THR   A 1 62  ? -30.603 -9.109  -6.215  1.000 30.014  0  172 THR   D O   1 ? 
ATOM   268  C  CB  . THR   A 1 62  ? -32.078 -6.313  -5.086  1.000 37.295  0  172 THR   D CB  1 ? 
ATOM   269  O  OG1 . THR   A 1 62  ? -33.371 -5.932  -4.625  1.000 46.034  0  172 THR   D OG1 1 ? 
ATOM   270  C  CG2 . THR   A 1 62  ? -31.969 -6.069  -6.580  1.000 36.253  0  172 THR   D CG2 1 ? 
ATOM   271  N  N   . LEU   A 1 63  ? -29.505 -8.059  -4.524  1.000 33.641  0  173 LEU   D N   1 ? 
ATOM   272  C  CA  . LEU   A 1 63  ? -28.182 -8.553  -4.888  1.000 31.810  0  173 LEU   D CA  1 ? 
ATOM   273  C  C   . LEU   A 1 63  ? -28.193 -10.081 -4.915  1.000 34.090  0  173 LEU   D C   1 ? 
ATOM   274  O  O   . LEU   A 1 63  ? -27.641 -10.687 -5.827  1.000 38.887  0  173 LEU   D O   1 ? 
ATOM   275  C  CB  . LEU   A 1 63  ? -27.138 -8.013  -3.908  1.000 35.567  0  173 LEU   D CB  1 ? 
ATOM   276  C  CG  . LEU   A 1 63  ? -25.701 -8.517  -4.100  1.000 37.639  0  173 LEU   D CG  1 ? 
ATOM   277  C  CD1 . LEU   A 1 63  ? -25.165 -8.174  -5.475  1.000 35.131  0  173 LEU   D CD1 1 ? 
ATOM   278  C  CD2 . LEU   A 1 63  ? -24.791 -7.957  -3.019  1.000 39.529  0  173 LEU   D CD2 1 ? 
ATOM   279  N  N   . CYS   A 1 64  ? -28.850 -10.690 -3.918  1.000 33.962  0  174 CYS   D N   1 ? 
ATOM   280  C  CA  . CYS   A 1 64  ? -28.940 -12.143 -3.824  1.000 34.551  0  174 CYS   D CA  1 ? 
ATOM   281  C  C   . CYS   A 1 64  ? -29.727 -12.709 -5.007  1.000 33.682  0  174 CYS   D C   1 ? 
ATOM   282  O  O   . CYS   A 1 64  ? -29.364 -13.748 -5.554  1.000 36.494  0  174 CYS   D O   1 ? 
ATOM   283  C  CB  . CYS   A 1 64  ? -29.562 -12.574 -2.503  1.000 34.743  0  174 CYS   D CB  1 ? 
ATOM   284  S  SG  . CYS   A 1 64  ? -28.494 -12.257 -1.075  1.000 42.208  0  174 CYS   D SG  1 ? 
ATOM   285  N  N   . ALA   A 1 65  ? -30.810 -12.021 -5.383  1.000 35.840  0  175 ALA   D N   1 ? 
ATOM   286  C  CA  . ALA   A 1 65  ? -31.672 -12.472 -6.467  1.000 34.907  0  175 ALA   D CA  1 ? 
ATOM   287  C  C   . ALA   A 1 65  ? -30.911 -12.428 -7.795  1.000 34.958  0  175 ALA   D C   1 ? 
ATOM   288  O  O   . ALA   A 1 65  ? -30.892 -13.407 -8.541  1.000 32.591  0  175 ALA   D O   1 ? 
ATOM   289  C  CB  . ALA   A 1 65  ? -32.924 -11.621 -6.513  1.000 34.368  0  175 ALA   D CB  1 ? 
ATOM   290  N  N   . VAL   A 1 66  ? -30.270 -11.287 -8.065  1.000 34.610  0  176 VAL   D N   1 ? 
ATOM   291  C  CA  . VAL   A 1 66  ? -29.511 -11.098 -9.290  1.000 32.407  0  176 VAL   D CA  1 ? 
ATOM   292  C  C   . VAL   A 1 66  ? -28.414 -12.165 -9.376  1.000 31.495  0  176 VAL   D C   1 ? 
ATOM   293  O  O   . VAL   A 1 66  ? -28.257 -12.808 -10.408 1.000 38.039  0  176 VAL   D O   1 ? 
ATOM   294  C  CB  . VAL   A 1 66  ? -28.925 -9.675  -9.359  1.000 36.891  0  176 VAL   D CB  1 ? 
ATOM   295  C  CG1 . VAL   A 1 66  ? -27.943 -9.517  -10.515 1.000 37.819  0  176 VAL   D CG1 1 ? 
ATOM   296  C  CG2 . VAL   A 1 66  ? -30.020 -8.616  -9.440  1.000 33.676  0  176 VAL   D CG2 1 ? 
ATOM   297  N  N   . MET   A 1 67  ? -27.675 -12.351 -8.273  1.000 35.528  0  177 MET   D N   1 ? 
ATOM   298  C  CA  . MET   A 1 67  ? -26.563 -13.298 -8.222  1.000 35.087  0  177 MET   D CA  1 ? 
ATOM   299  C  C   . MET   A 1 67  ? -27.069 -14.721 -8.478  1.000 34.540  0  177 MET   D C   1 ? 
ATOM   300  O  O   . MET   A 1 67  ? -26.426 -15.484 -9.190  1.000 32.492  0  177 MET   D O   1 ? 
ATOM   301  C  CB  . MET   A 1 67  ? -25.856 -13.237 -6.864  1.000 36.380  0  177 MET   D CB  1 ? 
ATOM   302  C  CG  . MET   A 1 67  ? -24.992 -12.002 -6.666  1.000 44.820  0  177 MET   D CG  1 ? 
ATOM   303  S  SD  . MET   A 1 67  ? -23.324 -12.192 -7.327  1.000 78.666  0  177 MET   D SD  1 ? 
ATOM   304  C  CE  . MET   A 1 67  ? -22.593 -13.262 -6.081  1.000 58.833  0  177 MET   D CE  1 ? 
ATOM   305  N  N   . THR   A 1 68  ? -28.230 -15.062 -7.894  1.000 29.848  0  178 THR   D N   1 ? 
ATOM   306  C  CA  . THR   A 1 68  ? -28.830 -16.382 -8.073  1.000 34.531  0  178 THR   D CA  1 ? 
ATOM   307  C  C   . THR   A 1 68  ? -29.013 -16.671 -9.569  1.000 32.083  0  178 THR   D C   1 ? 
ATOM   308  O  O   . THR   A 1 68  ? -28.740 -17.785 -10.024 1.000 31.695  0  178 THR   D O   1 ? 
ATOM   309  C  CB  . THR   A 1 68  ? -30.161 -16.453 -7.312  1.000 37.426  0  178 THR   D CB  1 ? 
ATOM   310  O  OG1 . THR   A 1 68  ? -29.812 -16.362 -5.932  1.000 36.558  0  178 THR   D OG1 1 ? 
ATOM   311  C  CG2 . THR   A 1 68  ? -30.920 -17.746 -7.561  1.000 36.117  0  178 THR   D CG2 1 ? 
ATOM   312  N  N   . ARG   A 1 69  ? -29.407 -15.636 -10.335 1.000 29.625  0  179 ARG   D N   1 ? 
ATOM   313  C  CA  . ARG   A 1 69  ? -29.712 -15.789 -11.755 1.000 32.624  0  179 ARG   D CA  1 ? 
ATOM   314  C  C   . ARG   A 1 69  ? -28.428 -15.846 -12.598 1.000 32.738  0  179 ARG   D C   1 ? 
ATOM   315  O  O   . ARG   A 1 69  ? -28.502 -16.013 -13.815 1.000 31.697  0  179 ARG   D O   1 ? 
ATOM   316  C  CB  . ARG   A 1 69  ? -30.638 -14.662 -12.233 1.000 30.808  0  179 ARG   D CB  1 ? 
ATOM   317  C  CG  . ARG   A 1 69  ? -32.062 -14.797 -11.716 1.000 31.451  0  179 ARG   D CG  1 ? 
ATOM   318  C  CD  . ARG   A 1 69  ? -33.021 -13.813 -12.364 1.000 28.552  0  179 ARG   D CD  1 ? 
ATOM   319  N  NE  . ARG   A 1 69  ? -32.861 -12.433 -11.891 1.000 25.540  0  179 ARG   D NE  1 ? 
ATOM   320  C  CZ  . ARG   A 1 69  ? -33.313 -11.952 -10.730 1.000 28.936  0  179 ARG   D CZ  1 ? 
ATOM   321  N  NH1 . ARG   A 1 69  ? -33.943 -12.741 -9.870  1.000 35.245  0  179 ARG   D NH1 1 ? 
ATOM   322  N  NH2 . ARG   A 1 69  ? -33.156 -10.671 -10.443 1.000 28.365  0  179 ARG   D NH2 1 ? 
ATOM   323  N  N   . LYS   A 1 70  ? -27.257 -15.721 -11.950 1.000 31.651  0  180 LYS   D N   1 ? 
ATOM   324  C  CA  . LYS   A 1 70  ? -25.982 -15.849 -12.648 1.000 33.718  0  180 LYS   D CA  1 ? 
ATOM   325  C  C   . LYS   A 1 70  ? -25.495 -17.300 -12.588 1.000 33.726  0  180 LYS   D C   1 ? 
ATOM   326  O  O   . LYS   A 1 70  ? -24.499 -17.644 -13.219 1.000 35.868  0  180 LYS   D O   1 ? 
ATOM   327  C  CB  . LYS   A 1 70  ? -24.930 -14.898 -12.073 1.000 37.448  0  180 LYS   D CB  1 ? 
ATOM   328  C  CG  . LYS   A 1 70  ? -25.341 -13.430 -12.022 1.000 40.289  0  180 LYS   D CG  1 ? 
ATOM   329  C  CD  . LYS   A 1 70  ? -25.926 -12.885 -13.321 1.000 36.561  0  180 LYS   D CD  1 ? 
ATOM   330  C  CE  . LYS   A 1 70  ? -26.261 -11.427 -13.224 1.000 40.192  0  180 LYS   D CE  1 ? 
ATOM   331  N  NZ  . LYS   A 1 70  ? -26.972 -10.947 -14.414 1.000 40.474  0  180 LYS   D NZ  1 ? 
ATOM   332  N  N   . PHE   A 1 71  ? -26.184 -18.135 -11.795 1.000 34.680  0  181 PHE   D N   1 ? 
ATOM   333  C  CA  . PHE   A 1 71  ? -25.925 -19.569 -11.776 1.000 34.413  0  181 PHE   D CA  1 ? 
ATOM   334  C  C   . PHE   A 1 71  ? -26.864 -20.251 -12.766 1.000 34.243  0  181 PHE   D C   1 ? 
ATOM   335  O  O   . PHE   A 1 71  ? -27.988 -19.802 -12.968 1.000 37.029  0  181 PHE   D O   1 ? 
ATOM   336  C  CB  . PHE   A 1 71  ? -26.118 -20.147 -10.370 1.000 34.528  0  181 PHE   D CB  1 ? 
ATOM   337  C  CG  . PHE   A 1 71  ? -25.133 -19.631 -9.331  1.000 43.100  0  181 PHE   D CG  1 ? 
ATOM   338  C  CD1 . PHE   A 1 71  ? -25.384 -18.454 -8.629  1.000 38.653  0  181 PHE   D CD1 1 ? 
ATOM   339  C  CD2 . PHE   A 1 71  ? -23.965 -20.333 -9.041  1.000 42.228  0  181 PHE   D CD2 1 ? 
ATOM   340  C  CE1 . PHE   A 1 71  ? -24.481 -17.984 -7.688  1.000 41.029  0  181 PHE   D CE1 1 ? 
ATOM   341  C  CE2 . PHE   A 1 71  ? -23.069 -19.858 -8.095  1.000 42.295  0  181 PHE   D CE2 1 ? 
ATOM   342  C  CZ  . PHE   A 1 71  ? -23.328 -18.686 -7.423  1.000 41.005  0  181 PHE   D CZ  1 ? 
ATOM   343  N  N   . SER   A 1 72  ? -26.381 -21.330 -13.391 1.000 36.041  0  182 SER   D N   1 ? 
ATOM   344  C  CA  . SER   A 1 72  ? -27.234 -22.191 -14.192 1.000 40.603  0  182 SER   D CA  1 ? 
ATOM   345  C  C   . SER   A 1 72  ? -28.261 -22.855 -13.280 1.000 36.902  0  182 SER   D C   1 ? 
ATOM   346  O  O   . SER   A 1 72  ? -27.982 -23.110 -12.108 1.000 34.989  0  182 SER   D O   1 ? 
ATOM   347  C  CB  . SER   A 1 72  ? -26.428 -23.218 -14.952 1.000 42.523  0  182 SER   D CB  1 ? 
ATOM   348  O  OG  . SER   A 1 72  ? -25.722 -24.073 -14.064 1.000 49.045  0  182 SER   D OG  1 ? 
ATOM   349  N  N   . LYS   A 1 73  ? -29.441 -23.140 -13.835 1.000 39.382  0  183 LYS   D N   1 ? 
ATOM   350  C  CA  . LYS   A 1 73  ? -30.542 -23.720 -13.075 1.000 44.894  0  183 LYS   D CA  1 ? 
ATOM   351  C  C   . LYS   A 1 73  ? -30.126 -25.087 -12.518 1.000 38.180  0  183 LYS   D C   1 ? 
ATOM   352  O  O   . LYS   A 1 73  ? -30.639 -25.524 -11.485 1.000 37.349  0  183 LYS   D O   1 ? 
ATOM   353  C  CB  . LYS   A 1 73  ? -31.788 -23.799 -13.971 1.000 47.901  0  183 LYS   D CB  1 ? 
ATOM   354  C  CG  . LYS   A 1 73  ? -32.990 -24.517 -13.377 1.000 55.744  0  183 LYS   D CG  1 ? 
ATOM   355  C  CD  . LYS   A 1 73  ? -34.223 -24.484 -14.271 1.000 72.551  0  183 LYS   D CD  1 ? 
ATOM   356  C  CE  . LYS   A 1 73  ? -35.311 -25.396 -13.792 1.000 79.277  0  183 LYS   D CE  1 ? 
ATOM   357  N  NZ  . LYS   A 1 73  ? -36.475 -25.357 -14.680 1.000 80.839  0  183 LYS   D NZ  1 ? 
ATOM   358  N  N   . SER   A 1 74  ? -29.136 -25.712 -13.169 1.000 35.587  0  184 SER   D N   1 ? 
ATOM   359  C  CA  . SER   A 1 74  ? -28.674 -27.041 -12.796 1.000 39.237  0  184 SER   D CA  1 ? 
ATOM   360  C  C   . SER   A 1 74  ? -27.810 -27.003 -11.524 1.000 38.239  0  184 SER   D C   1 ? 
ATOM   361  O  O   . SER   A 1 74  ? -27.447 -28.055 -11.004 1.000 36.807  0  184 SER   D O   1 ? 
ATOM   362  C  CB  . SER   A 1 74  ? -27.923 -27.670 -13.929 1.000 42.022  0  184 SER   D CB  1 ? 
ATOM   363  O  OG  . SER   A 1 74  ? -26.792 -26.885 -14.283 1.000 49.634  0  184 SER   D OG  1 ? 
ATOM   364  N  N   . GLN   A 1 75  ? -27.474 -25.788 -11.038 1.000 38.934  0  185 GLN   D N   1 ? 
ATOM   365  C  CA  . GLN   A 1 75  ? -26.611 -25.634 -9.865  1.000 43.960  0  185 GLN   D CA  1 ? 
ATOM   366  C  C   . GLN   A 1 75  ? -27.434 -25.302 -8.613  1.000 41.853  0  185 GLN   D C   1 ? 
ATOM   367  O  O   . GLN   A 1 75  ? -26.885 -25.247 -7.512  1.000 48.801  0  185 GLN   D O   1 ? 
ATOM   368  C  CB  . GLN   A 1 75  ? -25.561 -24.540 -10.094 1.000 42.537  0  185 GLN   D CB  1 ? 
ATOM   369  C  CG  . GLN   A 1 75  ? -24.377 -24.973 -10.951 1.000 45.650  0  185 GLN   D CG  1 ? 
ATOM   370  C  CD  . GLN   A 1 75  ? -23.498 -26.005 -10.273 1.000 52.734  0  185 GLN   D CD  1 ? 
ATOM   371  O  OE1 . GLN   A 1 75  ? -23.857 -27.183 -10.154 1.000 52.441  0  185 GLN   D OE1 1 ? 
ATOM   372  N  NE2 . GLN   A 1 75  ? -22.314 -25.578 -9.854  1.000 52.214  0  185 GLN   D NE2 1 ? 
ATOM   373  N  N   . LEU   A 1 76  ? -28.745 -25.099 -8.779  1.000 37.827  0  186 LEU   D N   1 ? 
ATOM   374  C  CA  . LEU   A 1 76  ? -29.592 -24.659 -7.677  1.000 42.411  0  186 LEU   D CA  1 ? 
ATOM   375  C  C   . LEU   A 1 76  ? -29.618 -25.728 -6.583  1.000 42.152  0  186 LEU   D C   1 ? 
ATOM   376  O  O   . LEU   A 1 76  ? -29.572 -25.404 -5.399  1.000 42.284  0  186 LEU   D O   1 ? 
ATOM   377  C  CB  . LEU   A 1 76  ? -30.996 -24.330 -8.183  1.000 41.852  0  186 LEU   D CB  1 ? 
ATOM   378  C  CG  . LEU   A 1 76  ? -31.095 -23.158 -9.169  1.000 48.249  0  186 LEU   D CG  1 ? 
ATOM   379  C  CD1 . LEU   A 1 76  ? -32.507 -23.018 -9.691  1.000 49.105  0  186 LEU   D CD1 1 ? 
ATOM   380  C  CD2 . LEU   A 1 76  ? -30.630 -21.850 -8.540  1.000 44.882  0  186 LEU   D CD2 1 ? 
ATOM   381  N  N   . SER   A 1 77  ? -29.652 -27.003 -6.994  1.000 39.068  0  187 SER   D N   1 ? 
ATOM   382  C  CA  . SER   A 1 77  ? -29.723 -28.111 -6.051  1.000 42.090  0  187 SER   D CA  1 ? 
ATOM   383  C  C   . SER   A 1 77  ? -28.457 -28.161 -5.193  1.000 42.988  0  187 SER   D C   1 ? 
ATOM   384  O  O   . SER   A 1 77  ? -28.527 -28.494 -4.012  1.000 42.205  0  187 SER   D O   1 ? 
ATOM   385  C  CB  . SER   A 1 77  ? -29.961 -29.420 -6.760  1.000 39.321  0  187 SER   D CB  1 ? 
ATOM   386  O  OG  . SER   A 1 77  ? -28.928 -29.686 -7.694  1.000 65.001  0  187 SER   D OG  1 ? 
ATOM   387  N  N   . LEU   A 1 78  ? -27.300 -27.823 -5.802  1.000 42.247  0  188 LEU   D N   1 ? 
ATOM   388  C  CA  . LEU   A 1 78  ? -26.027 -27.798 -5.087  1.000 37.381  0  188 LEU   D CA  1 ? 
ATOM   389  C  C   . LEU   A 1 78  ? -25.975 -26.569 -4.179  1.000 39.152  0  188 LEU   D C   1 ? 
ATOM   390  O  O   . LEU   A 1 78  ? -25.385 -26.618 -3.105  1.000 39.761  0  188 LEU   D O   1 ? 
ATOM   391  C  CB  . LEU   A 1 78  ? -24.849 -27.817 -6.064  1.000 39.995  0  188 LEU   D CB  1 ? 
ATOM   392  C  CG  . LEU   A 1 78  ? -23.449 -27.666 -5.442  1.000 48.218  0  188 LEU   D CG  1 ? 
ATOM   393  C  CD1 . LEU   A 1 78  ? -23.177 -28.722 -4.378  1.000 46.524  0  188 LEU   D CD1 1 ? 
ATOM   394  C  CD2 . LEU   A 1 78  ? -22.372 -27.716 -6.514  1.000 50.055  0  188 LEU   D CD2 1 ? 
ATOM   395  N  N   . LEU   A 1 79  ? -26.558 -25.455 -4.649  1.000 41.292  0  189 LEU   D N   1 ? 
ATOM   396  C  CA  . LEU   A 1 79  ? -26.618 -24.227 -3.868  1.000 40.361  0  189 LEU   D CA  1 ? 
ATOM   397  C  C   . LEU   A 1 79  ? -27.441 -24.475 -2.601  1.000 38.222  0  189 LEU   D C   1 ? 
ATOM   398  O  O   . LEU   A 1 79  ? -27.032 -24.094 -1.508  1.000 38.151  0  189 LEU   D O   1 ? 
ATOM   399  C  CB  . LEU   A 1 79  ? -27.211 -23.108 -4.727  1.000 43.882  0  189 LEU   D CB  1 ? 
ATOM   400  C  CG  . LEU   A 1 79  ? -27.298 -21.723 -4.078  1.000 47.781  0  189 LEU   D CG  1 ? 
ATOM   401  C  CD1 . LEU   A 1 79  ? -25.946 -21.242 -3.585  1.000 57.078  0  189 LEU   D CD1 1 ? 
ATOM   402  C  CD2 . LEU   A 1 79  ? -27.886 -20.728 -5.055  1.000 51.171  0  189 LEU   D CD2 1 ? 
ATOM   403  N  N   . CYS   A 1 80  ? -28.585 -25.153 -2.770  1.000 37.445  0  190 CYS   D N   1 ? 
ATOM   404  C  CA  . CYS   A 1 80  ? -29.452 -25.531 -1.660  1.000 37.335  0  190 CYS   D CA  1 ? 
ATOM   405  C  C   . CYS   A 1 80  ? -28.696 -26.434 -0.677  1.000 38.339  0  190 CYS   D C   1 ? 
ATOM   406  O  O   . CYS   A 1 80  ? -28.707 -26.192 0.525   1.000 38.897  0  190 CYS   D O   1 ? 
ATOM   407  C  CB  . CYS   A 1 80  ? -30.702 -26.234 -2.178  1.000 37.231  0  190 CYS   D CB  1 ? 
ATOM   408  S  SG  . CYS   A 1 80  ? -31.734 -26.935 -0.871  1.000 41.034  0  190 CYS   D SG  1 ? 
ATOM   409  N  N   . GLU   A 1 81  ? -28.042 -27.472 -1.212  1.000 40.015  0  191 GLU   D N   1 ? 
ATOM   410  C  CA  . GLU   A 1 81  ? -27.287 -28.423 -0.407  1.000 48.068  0  191 GLU   D CA  1 ? 
ATOM   411  C  C   . GLU   A 1 81  ? -26.266 -27.681 0.462   1.000 47.085  0  191 GLU   D C   1 ? 
ATOM   412  O  O   . GLU   A 1 81  ? -26.192 -27.915 1.669   1.000 46.665  0  191 GLU   D O   1 ? 
ATOM   413  C  CB  . GLU   A 1 81  ? -26.598 -29.446 -1.317  1.000 56.140  0  191 GLU   D CB  1 ? 
ATOM   414  C  CG  . GLU   A 1 81  ? -25.700 -30.431 -0.569  1.000 68.272  0  191 GLU   D CG  1 ? 
ATOM   415  C  CD  . GLU   A 1 81  ? -25.042 -31.489 -1.448  1.000 78.590  0  191 GLU   D CD  1 ? 
ATOM   416  O  OE1 . GLU   A 1 81  ? -24.279 -32.311 -0.899  1.000 75.113  0  191 GLU   D OE1 1 ? 
ATOM   417  O  OE2 . GLU   A 1 81  ? -25.292 -31.494 -2.674  1.000 84.600  0  191 GLU   D OE2 1 ? 
ATOM   418  N  N   . THR   A 1 82  ? -25.486 -26.788 -0.168  1.000 37.283  0  192 THR   D N   1 ? 
ATOM   419  C  CA  . THR   A 1 82  ? -24.406 -26.086 0.511   1.000 36.339  0  192 THR   D CA  1 ? 
ATOM   420  C  C   . THR   A 1 82  ? -24.988 -25.145 1.569   1.000 38.086  0  192 THR   D C   1 ? 
ATOM   421  O  O   . THR   A 1 82  ? -24.371 -24.928 2.612   1.000 36.379  0  192 THR   D O   1 ? 
ATOM   422  C  CB  . THR   A 1 82  ? -23.553 -25.330 -0.510  1.000 38.513  0  192 THR   D CB  1 ? 
ATOM   423  O  OG1 . THR   A 1 82  ? -23.273 -26.252 -1.558  1.000 37.828  0  192 THR   D OG1 1 ? 
ATOM   424  C  CG2 . THR   A 1 82  ? -22.254 -24.820 0.086   1.000 37.160  0  192 THR   D CG2 1 ? 
ATOM   425  N  N   . HIS   A 1 83  ? -26.175 -24.587 1.284   1.000 35.680  0  193 HIS   D N   1 ? 
ATOM   426  C  CA  . HIS   A 1 83  ? -26.848 -23.677 2.206   1.000 35.773  0  193 HIS   D CA  1 ? 
ATOM   427  C  C   . HIS   A 1 83  ? -27.224 -24.433 3.484   1.000 38.144  0  193 HIS   D C   1 ? 
ATOM   428  O  O   . HIS   A 1 83  ? -26.932 -23.973 4.590   1.000 36.664  0  193 HIS   D O   1 ? 
ATOM   429  C  CB  . HIS   A 1 83  ? -28.055 -23.016 1.518   1.000 34.278  0  193 HIS   D CB  1 ? 
ATOM   430  C  CG  . HIS   A 1 83  ? -28.743 -21.965 2.329   1.000 32.016  0  193 HIS   D CG  1 ? 
ATOM   431  N  ND1 . HIS   A 1 83  ? -28.967 -20.697 1.837   1.000 30.709  0  193 HIS   D ND1 1 ? 
ATOM   432  C  CD2 . HIS   A 1 83  ? -29.188 -21.950 3.601   1.000 36.773  0  193 HIS   D CD2 1 ? 
ATOM   433  C  CE1 . HIS   A 1 83  ? -29.559 -19.963 2.771   1.000 40.431  0  193 HIS   D CE1 1 ? 
ATOM   434  N  NE2 . HIS   A 1 83  ? -29.716 -20.708 3.844   1.000 36.395  0  193 HIS   D NE2 1 ? 
ATOM   435  N  N   . LEU   A 1 84  ? -27.864 -25.600 3.317   1.000 42.103  0  194 LEU   D N   1 ? 
ATOM   436  C  CA  . LEU   A 1 84  ? -28.283 -26.421 4.448   1.000 48.347  0  194 LEU   D CA  1 ? 
ATOM   437  C  C   . LEU   A 1 84  ? -27.070 -26.761 5.307   1.000 45.459  0  194 LEU   D C   1 ? 
ATOM   438  O  O   . LEU   A 1 84  ? -27.130 -26.691 6.531   1.000 47.688  0  194 LEU   D O   1 ? 
ATOM   439  C  CB  . LEU   A 1 84  ? -28.978 -27.696 3.970   1.000 39.688  0  194 LEU   D CB  1 ? 
ATOM   440  C  CG  . LEU   A 1 84  ? -30.238 -27.511 3.120   1.000 46.436  0  194 LEU   D CG  1 ? 
ATOM   441  C  CD1 . LEU   A 1 84  ? -30.866 -28.859 2.852   1.000 46.531  0  194 LEU   D CD1 1 ? 
ATOM   442  C  CD2 . LEU   A 1 84  ? -31.239 -26.567 3.764   1.000 50.138  0  194 LEU   D CD2 1 ? 
ATOM   443  N  N   . ARG   A 1 85  ? -25.973 -27.125 4.642   1.000 47.258  0  195 ARG   D N   1 ? 
ATOM   444  C  CA  . ARG   A 1 85  ? -24.781 -27.604 5.314   1.000 48.399  0  195 ARG   D CA  1 ? 
ATOM   445  C  C   . ARG   A 1 85  ? -24.174 -26.476 6.152   1.000 53.354  0  195 ARG   D C   1 ? 
ATOM   446  O  O   . ARG   A 1 85  ? -23.849 -26.675 7.324   1.000 46.422  0  195 ARG   D O   1 ? 
ATOM   447  C  CB  . ARG   A 1 85  ? -23.799 -28.141 4.267   1.000 49.806  0  195 ARG   D CB  1 ? 
ATOM   448  C  CG  . ARG   A 1 85  ? -22.797 -29.143 4.809   1.000 54.137  0  195 ARG   D CG  1 ? 
ATOM   449  C  CD  . ARG   A 1 85  ? -21.952 -29.765 3.710   1.000 54.366  0  195 ARG   D CD  1 ? 
ATOM   450  N  NE  . ARG   A 1 85  ? -21.066 -28.785 3.064   1.000 68.436  0  195 ARG   D NE  1 ? 
ATOM   451  C  CZ  . ARG   A 1 85  ? -21.014 -28.501 1.751   1.000 73.646  0  195 ARG   D CZ  1 ? 
ATOM   452  N  NH1 . ARG   A 1 85  ? -21.809 -29.122 0.886   1.000 80.330  0  195 ARG   D NH1 1 ? 
ATOM   453  N  NH2 . ARG   A 1 85  ? -20.153 -27.596 1.312   1.000 67.272  0  195 ARG   D NH2 1 ? 
ATOM   454  N  N   . ARG   A 1 86  ? -24.091 -25.275 5.561   1.000 54.146  0  196 ARG   D N   1 ? 
ATOM   455  C  CA  . ARG   A 1 86  ? -23.431 -24.150 6.204   1.000 61.074  0  196 ARG   D CA  1 ? 
ATOM   456  C  C   . ARG   A 1 86  ? -24.217 -23.724 7.445   1.000 55.234  0  196 ARG   D C   1 ? 
ATOM   457  O  O   . ARG   A 1 86  ? -23.637 -23.527 8.510   1.000 66.446  0  196 ARG   D O   1 ? 
ATOM   458  C  CB  . ARG   A 1 86  ? -23.292 -22.943 5.266   1.000 60.009  0  196 ARG   D CB  1 ? 
ATOM   459  C  CG  . ARG   A 1 86  ? -22.148 -22.028 5.674   1.000 70.799  0  196 ARG   D CG  1 ? 
ATOM   460  C  CD  . ARG   A 1 86  ? -22.368 -20.561 5.348   1.000 64.959  0  196 ARG   D CD  1 ? 
ATOM   461  N  NE  . ARG   A 1 86  ? -21.133 -19.800 5.591   1.000 71.177  0  196 ARG   D NE  1 ? 
ATOM   462  C  CZ  . ARG   A 1 86  ? -21.047 -18.495 5.849   1.000 74.754  0  196 ARG   D CZ  1 ? 
ATOM   463  N  NH1 . ARG   A 1 86  ? -22.139 -17.779 6.072   1.000 82.619  0  196 ARG   D NH1 1 ? 
ATOM   464  N  NH2 . ARG   A 1 86  ? -19.857 -17.936 5.998   1.000 77.506  0  196 ARG   D NH2 1 ? 
ATOM   465  N  N   . GLU   A 1 87  ? -25.542 -23.585 7.288   1.000 54.605  0  197 GLU   D N   1 ? 
ATOM   466  C  CA  . GLU   A 1 87  ? -26.398 -23.034 8.332   1.000 55.755  0  197 GLU   D CA  1 ? 
ATOM   467  C  C   . GLU   A 1 87  ? -26.821 -24.124 9.320   1.000 45.157  0  197 GLU   D C   1 ? 
ATOM   468  O  O   . GLU   A 1 87  ? -27.484 -23.833 10.308  1.000 44.947  0  197 GLU   D O   1 ? 
ATOM   469  C  CB  . GLU   A 1 87  ? -27.621 -22.357 7.708   1.000 58.904  0  197 GLU   D CB  1 ? 
ATOM   470  C  CG  . GLU   A 1 87  ? -27.280 -21.118 6.883   1.000 60.831  0  197 GLU   D CG  1 ? 
ATOM   471  C  CD  . GLU   A 1 87  ? -26.601 -20.005 7.667   1.000 67.077  0  197 GLU   D CD  1 ? 
ATOM   472  O  OE1 . GLU   A 1 87  ? -25.401 -20.150 7.987   1.000 71.328  0  197 GLU   D OE1 1 ? 
ATOM   473  O  OE2 . GLU   A 1 87  ? -27.287 -19.014 8.001   1.000 70.037  0  197 GLU   D OE2 1 ? 
ATOM   474  N  N   . GLY   A 1 88  ? -26.447 -25.377 9.032   1.000 51.579  0  198 GLY   D N   1 ? 
ATOM   475  C  CA  . GLY   A 1 88  ? -26.730 -26.492 9.924   1.000 50.829  0  198 GLY   D CA  1 ? 
ATOM   476  C  C   . GLY   A 1 88  ? -28.224 -26.811 9.975   1.000 53.092  0  198 GLY   D C   1 ? 
ATOM   477  O  O   . GLY   A 1 88  ? -28.735 -27.223 11.012  1.000 55.701  0  198 GLY   D O   1 ? 
ATOM   478  N  N   . LEU   A 1 89  ? -28.912 -26.609 8.842   1.000 56.468  0  199 LEU   D N   1 ? 
ATOM   479  C  CA  . LEU   A 1 89  ? -30.335 -26.905 8.735   1.000 56.546  0  199 LEU   D CA  1 ? 
ATOM   480  C  C   . LEU   A 1 89  ? -30.510 -28.393 8.448   1.000 52.203  0  199 LEU   D C   1 ? 
ATOM   481  O  O   . LEU   A 1 89  ? -29.635 -29.021 7.857   1.000 55.104  0  199 LEU   D O   1 ? 
ATOM   482  C  CB  . LEU   A 1 89  ? -30.970 -26.055 7.635   1.000 56.746  0  199 LEU   D CB  1 ? 
ATOM   483  C  CG  . LEU   A 1 89  ? -30.799 -24.537 7.763   1.000 61.810  0  199 LEU   D CG  1 ? 
ATOM   484  C  CD1 . LEU   A 1 89  ? -31.386 -23.836 6.546   1.000 57.835  0  199 LEU   D CD1 1 ? 
ATOM   485  C  CD2 . LEU   A 1 89  ? -31.426 -24.005 9.040   1.000 68.075  0  199 LEU   D CD2 1 ? 
ATOM   486  N  N   . GLY   A 1 90  ? -31.659 -28.939 8.860   1.000 50.603  0  200 GLY   D N   1 ? 
ATOM   487  C  CA  . GLY   A 1 90  ? -31.985 -30.331 8.604   1.000 47.630  0  200 GLY   D CA  1 ? 
ATOM   488  C  C   . GLY   A 1 90  ? -32.408 -30.536 7.152   1.000 50.594  0  200 GLY   D C   1 ? 
ATOM   489  O  O   . GLY   A 1 90  ? -32.739 -29.577 6.458   1.000 54.838  0  200 GLY   D O   1 ? 
ATOM   490  N  N   . GLN   A 1 91  ? -32.445 -31.806 6.724   1.000 58.311  0  201 GLN   D N   1 ? 
ATOM   491  C  CA  . GLN   A 1 91  ? -32.811 -32.160 5.357   1.000 64.057  0  201 GLN   D CA  1 ? 
ATOM   492  C  C   . GLN   A 1 91  ? -34.314 -31.947 5.141   1.000 64.687  0  201 GLN   D C   1 ? 
ATOM   493  O  O   . GLN   A 1 91  ? -34.801 -32.053 4.016   1.000 63.315  0  201 GLN   D O   1 ? 
ATOM   494  C  CB  . GLN   A 1 91  ? -32.402 -33.603 5.054   1.000 64.178  0  201 GLN   D CB  1 ? 
ATOM   495  C  CG  . GLN   A 1 91  ? -30.895 -33.802 4.900   1.000 73.209  0  201 GLN   D CG  1 ? 
ATOM   496  C  CD  . GLN   A 1 91  ? -30.349 -33.252 3.597   1.000 78.234  0  201 GLN   D CD  1 ? 
ATOM   497  O  OE1 . GLN   A 1 91  ? -29.512 -32.341 3.579   1.000 80.922  0  201 GLN   D OE1 1 ? 
ATOM   498  N  NE2 . GLN   A 1 91  ? -30.817 -33.809 2.488   1.000 85.802  0  201 GLN   D NE2 1 ? 
ATOM   499  N  N   . ASP   A 1 92  ? -35.036 -31.639 6.230   1.000 63.356  0  202 ASP   D N   1 ? 
ATOM   500  C  CA  . ASP   A 1 92  ? -36.447 -31.294 6.156   1.000 62.243  0  202 ASP   D CA  1 ? 
ATOM   501  C  C   . ASP   A 1 92  ? -36.613 -29.916 5.504   1.000 60.276  0  202 ASP   D C   1 ? 
ATOM   502  O  O   . ASP   A 1 92  ? -37.713 -29.558 5.089   1.000 71.107  0  202 ASP   D O   1 ? 
ATOM   503  C  CB  . ASP   A 1 92  ? -37.096 -31.345 7.533   1.000 71.336  0  202 ASP   D CB  1 ? 
ATOM   504  C  CG  . ASP   A 1 92  ? -36.539 -30.366 8.561   1.000 80.276  0  202 ASP   D CG  1 ? 
ATOM   505  O  OD1 . ASP   A 1 92  ? -35.300 -30.293 8.687   1.000 82.685  0  202 ASP   D OD1 1 ? 
ATOM   506  O  OD2 . ASP   A 1 92  ? -37.351 -29.737 9.274   1.000 89.881  0  202 ASP   D OD2 1 ? 
ATOM   507  N  N   . GLN   A 1 93  ? -35.505 -29.155 5.412   1.000 56.145  0  203 GLN   D N   1 ? 
ATOM   508  C  CA  . GLN   A 1 93  ? -35.533 -27.803 4.867   1.000 53.218  0  203 GLN   D CA  1 ? 
ATOM   509  C  C   . GLN   A 1 93  ? -34.998 -27.787 3.431   1.000 44.359  0  203 GLN   D C   1 ? 
ATOM   510  O  O   . GLN   A 1 93  ? -34.816 -26.720 2.855   1.000 49.216  0  203 GLN   D O   1 ? 
ATOM   511  C  CB  . GLN   A 1 93  ? -34.715 -26.864 5.757   1.000 52.396  0  203 GLN   D CB  1 ? 
ATOM   512  C  CG  . GLN   A 1 93  ? -35.206 -26.796 7.198   1.000 51.175  0  203 GLN   D CG  1 ? 
ATOM   513  C  CD  . GLN   A 1 93  ? -36.679 -26.476 7.301   1.000 49.867  0  203 GLN   D CD  1 ? 
ATOM   514  O  OE1 . GLN   A 1 93  ? -37.484 -27.289 7.768   1.000 61.243  0  203 GLN   D OE1 1 ? 
ATOM   515  N  NE2 . GLN   A 1 93  ? -37.057 -25.309 6.800   1.000 53.548  0  203 GLN   D NE2 1 ? 
ATOM   516  N  N   . ALA   A 1 94  ? -34.806 -28.973 2.842   1.000 48.587  0  204 ALA   D N   1 ? 
ATOM   517  C  CA  . ALA   A 1 94  ? -34.277 -29.083 1.489   1.000 52.738  0  204 ALA   D CA  1 ? 
ATOM   518  C  C   . ALA   A 1 94  ? -35.287 -28.535 0.482   1.000 55.396  0  204 ALA   D C   1 ? 
ATOM   519  O  O   . ALA   A 1 94  ? -34.930 -27.741 -0.387  1.000 58.518  0  204 ALA   D O   1 ? 
ATOM   520  C  CB  . ALA   A 1 94  ? -33.920 -30.523 1.187   1.000 55.000  0  204 ALA   D CB  1 ? 
ATOM   521  N  N   . GLU   A 1 95  ? -36.554 -28.953 0.630   1.000 53.074  0  205 GLU   D N   1 ? 
ATOM   522  C  CA  . GLU   A 1 95  ? -37.613 -28.571 -0.294  1.000 60.125  0  205 GLU   D CA  1 ? 
ATOM   523  C  C   . GLU   A 1 95  ? -37.834 -27.048 -0.251  1.000 60.478  0  205 GLU   D C   1 ? 
ATOM   524  O  O   . GLU   A 1 95  ? -37.805 -26.397 -1.294  1.000 55.593  0  205 GLU   D O   1 ? 
ATOM   525  C  CB  . GLU   A 1 95  ? -38.883 -29.379 -0.005  1.000 65.305  0  205 GLU   D CB  1 ? 
ATOM   526  C  CG  . GLU   A 1 95  ? -40.006 -29.137 -1.011  1.000 83.986  0  205 GLU   D CG  1 ? 
ATOM   527  C  CD  . GLU   A 1 95  ? -41.167 -30.117 -0.903  1.000 92.467  0  205 GLU   D CD  1 ? 
ATOM   528  O  OE1 . GLU   A 1 95  ? -41.468 -30.786 -1.915  1.000 98.313  0  205 GLU   D OE1 1 ? 
ATOM   529  O  OE2 . GLU   A 1 95  ? -41.759 -30.224 0.193   1.000 80.912  0  205 GLU   D OE2 1 ? 
ATOM   530  N  N   . PRO   A 1 96  ? -38.047 -26.427 0.945   1.000 49.112  0  206 PRO   D N   1 ? 
ATOM   531  C  CA  . PRO   A 1 96  ? -38.321 -24.985 1.018   1.000 44.994  0  206 PRO   D CA  1 ? 
ATOM   532  C  C   . PRO   A 1 96  ? -37.155 -24.072 0.617   1.000 42.833  0  206 PRO   D C   1 ? 
ATOM   533  O  O   . PRO   A 1 96  ? -37.373 -23.018 0.026   1.000 36.769  0  206 PRO   D O   1 ? 
ATOM   534  C  CB  . PRO   A 1 96  ? -38.744 -24.781 2.498   1.000 45.714  0  206 PRO   D CB  1 ? 
ATOM   535  C  CG  . PRO   A 1 96  ? -38.108 -25.941 3.229   1.000 47.838  0  206 PRO   D CG  1 ? 
ATOM   536  C  CD  . PRO   A 1 96  ? -38.168 -27.090 2.251   1.000 47.538  0  206 PRO   D CD  1 ? 
ATOM   537  N  N   . VAL   A 1 97  ? -35.921 -24.475 0.958   1.000 39.501  0  207 VAL   D N   1 ? 
ATOM   538  C  CA  . VAL   A 1 97  ? -34.737 -23.687 0.621   1.000 39.763  0  207 VAL   D CA  1 ? 
ATOM   539  C  C   . VAL   A 1 97  ? -34.526 -23.720 -0.899  1.000 41.349  0  207 VAL   D C   1 ? 
ATOM   540  O  O   . VAL   A 1 97  ? -34.225 -22.694 -1.507  1.000 38.808  0  207 VAL   D O   1 ? 
ATOM   541  C  CB  . VAL   A 1 97  ? -33.478 -24.167 1.376   1.000 33.290  0  207 VAL   D CB  1 ? 
ATOM   542  C  CG1 . VAL   A 1 97  ? -32.200 -23.559 0.806   1.000 31.267  0  207 VAL   D CG1 1 ? 
ATOM   543  C  CG2 . VAL   A 1 97  ? -33.579 -23.884 2.871   1.000 33.373  0  207 VAL   D CG2 1 ? 
ATOM   544  N  N   . LEU   A 1 98  ? -34.678 -24.908 -1.499  1.000 40.430  0  208 LEU   D N   1 ? 
ATOM   545  C  CA  . LEU   A 1 98  ? -34.527 -25.061 -2.941  1.000 45.866  0  208 LEU   D CA  1 ? 
ATOM   546  C  C   . LEU   A 1 98  ? -35.561 -24.189 -3.654  1.000 41.916  0  208 LEU   D C   1 ? 
ATOM   547  O  O   . LEU   A 1 98  ? -35.232 -23.499 -4.614  1.000 45.841  0  208 LEU   D O   1 ? 
ATOM   548  C  CB  . LEU   A 1 98  ? -34.660 -26.529 -3.353  1.000 45.051  0  208 LEU   D CB  1 ? 
ATOM   549  C  CG  . LEU   A 1 98  ? -34.463 -26.827 -4.844  1.000 45.863  0  208 LEU   D CG  1 ? 
ATOM   550  C  CD1 . LEU   A 1 98  ? -33.039 -26.508 -5.290  1.000 46.138  0  208 LEU   D CD1 1 ? 
ATOM   551  C  CD2 . LEU   A 1 98  ? -34.810 -28.269 -5.160  1.000 43.903  0  208 LEU   D CD2 1 ? 
ATOM   552  N  N   . GLU   A 1 99  ? -36.809 -24.223 -3.159  1.000 39.461  0  209 GLU   D N   1 ? 
ATOM   553  C  CA  . GLU   A 1 99  ? -37.908 -23.473 -3.757  1.000 38.376  0  209 GLU   D CA  1 ? 
ATOM   554  C  C   . GLU   A 1 99  ? -37.557 -21.981 -3.801  1.000 33.163  0  209 GLU   D C   1 ? 
ATOM   555  O  O   . GLU   A 1 99  ? -37.791 -21.317 -4.811  1.000 32.189  0  209 GLU   D O   1 ? 
ATOM   556  C  CB  . GLU   A 1 99  ? -39.205 -23.708 -2.977  1.000 43.345  0  209 GLU   D CB  1 ? 
ATOM   557  C  CG  . GLU   A 1 99  ? -40.449 -23.181 -3.690  1.000 51.578  0  209 GLU   D CG  1 ? 
ATOM   558  C  CD  . GLU   A 1 99  ? -41.751 -23.395 -2.929  1.000 61.250  0  209 GLU   D CD  1 ? 
ATOM   559  O  OE1 . GLU   A 1 99  ? -41.986 -24.534 -2.469  1.000 63.800  0  209 GLU   D OE1 1 ? 
ATOM   560  O  OE2 . GLU   A 1 99  ? -42.555 -22.439 -2.845  1.000 58.051  0  209 GLU   D OE2 1 ? 
ATOM   561  N  N   . VAL   A 1 100 ? -36.992 -21.465 -2.696  1.000 30.616  0  210 VAL   D N   1 ? 
ATOM   562  C  CA  . VAL   A 1 100 ? -36.625 -20.056 -2.601  1.000 34.568  0  210 VAL   D CA  1 ? 
ATOM   563  C  C   . VAL   A 1 100 ? -35.646 -19.717 -3.726  1.000 34.317  0  210 VAL   D C   1 ? 
ATOM   564  O  O   . VAL   A 1 100 ? -35.771 -18.678 -4.360  1.000 39.316  0  210 VAL   D O   1 ? 
ATOM   565  C  CB  . VAL   A 1 100 ? -36.031 -19.696 -1.221  1.000 37.442  0  210 VAL   D CB  1 ? 
ATOM   566  C  CG1 . VAL   A 1 100 ? -35.382 -18.311 -1.217  1.000 38.501  0  210 VAL   D CG1 1 ? 
ATOM   567  C  CG2 . VAL   A 1 100 ? -37.070 -19.793 -0.114  1.000 35.639  0  210 VAL   D CG2 1 ? 
ATOM   568  N  N   . TYR   A 1 101 ? -34.678 -20.612 -3.962  1.000 36.353  0  211 TYR   D N   1 ? 
ATOM   569  C  CA  . TYR   A 1 101 ? -33.634 -20.384 -4.950  1.000 37.748  0  211 TYR   D CA  1 ? 
ATOM   570  C  C   . TYR   A 1 101 ? -34.202 -20.506 -6.370  1.000 37.620  0  211 TYR   D C   1 ? 
ATOM   571  O  O   . TYR   A 1 101 ? -33.813 -19.749 -7.253  1.000 39.780  0  211 TYR   D O   1 ? 
ATOM   572  C  CB  . TYR   A 1 101 ? -32.473 -21.351 -4.689  1.000 38.412  0  211 TYR   D CB  1 ? 
ATOM   573  C  CG  . TYR   A 1 101 ? -31.515 -20.902 -3.590  1.000 41.112  0  211 TYR   D CG  1 ? 
ATOM   574  C  CD1 . TYR   A 1 101 ? -31.012 -19.605 -3.561  1.000 42.657  0  211 TYR   D CD1 1 ? 
ATOM   575  C  CD2 . TYR   A 1 101 ? -31.148 -21.759 -2.561  1.000 40.231  0  211 TYR   D CD2 1 ? 
ATOM   576  C  CE1 . TYR   A 1 101 ? -30.139 -19.190 -2.570  1.000 42.171  0  211 TYR   D CE1 1 ? 
ATOM   577  C  CE2 . TYR   A 1 101 ? -30.281 -21.354 -1.557  1.000 38.203  0  211 TYR   D CE2 1 ? 
ATOM   578  C  CZ  . TYR   A 1 101 ? -29.773 -20.067 -1.563  1.000 40.615  0  211 TYR   D CZ  1 ? 
ATOM   579  O  OH  . TYR   A 1 101 ? -28.925 -19.656 -0.575  1.000 45.197  0  211 TYR   D OH  1 ? 
ATOM   580  N  N   . GLN   A 1 102 ? -35.112 -21.469 -6.580  1.000 37.139  0  212 GLN   D N   1 ? 
ATOM   581  C  CA  . GLN   A 1 102 ? -35.720 -21.683 -7.892  1.000 35.684  0  212 GLN   D CA  1 ? 
ATOM   582  C  C   . GLN   A 1 102 ? -36.589 -20.482 -8.274  1.000 36.403  0  212 GLN   D C   1 ? 
ATOM   583  O  O   . GLN   A 1 102 ? -36.520 -19.999 -9.403  1.000 41.808  0  212 GLN   D O   1 ? 
ATOM   584  C  CB  . GLN   A 1 102 ? -36.560 -22.960 -7.910  1.000 35.624  0  212 GLN   D CB  1 ? 
ATOM   585  C  CG  . GLN   A 1 102 ? -35.750 -24.236 -7.737  1.000 41.554  0  212 GLN   D CG  1 ? 
ATOM   586  C  CD  . GLN   A 1 102 ? -36.612 -25.476 -7.660  1.000 41.236  0  212 GLN   D CD  1 ? 
ATOM   587  O  OE1 . GLN   A 1 102 ? -37.556 -25.554 -6.869  1.000 58.469  0  212 GLN   D OE1 1 ? 
ATOM   588  N  NE2 . GLN   A 1 102 ? -36.307 -26.455 -8.500  1.000 45.253  0  212 GLN   D NE2 1 ? 
ATOM   589  N  N   . ARG   A 1 103 ? -37.389 -19.998 -7.315  1.000 36.395  0  213 ARG   D N   1 ? 
ATOM   590  C  CA  . ARG   A 1 103 ? -38.359 -18.946 -7.583  1.000 37.498  0  213 ARG   D CA  1 ? 
ATOM   591  C  C   . ARG   A 1 103 ? -37.654 -17.590 -7.697  1.000 36.605  0  213 ARG   D C   1 ? 
ATOM   592  O  O   . ARG   A 1 103 ? -38.158 -16.692 -8.366  1.000 34.496  0  213 ARG   D O   1 ? 
ATOM   593  C  CB  . ARG   A 1 103 ? -39.474 -18.978 -6.534  1.000 38.209  0  213 ARG   D CB  1 ? 
ATOM   594  C  CG  . ARG   A 1 103 ? -40.300 -20.257 -6.603  1.000 38.850  0  213 ARG   D CG  1 ? 
ATOM   595  C  CD  . ARG   A 1 103 ? -41.408 -20.296 -5.577  1.000 44.213  0  213 ARG   D CD  1 ? 
ATOM   596  N  NE  . ARG   A 1 103 ? -42.451 -19.301 -5.847  1.000 47.990  0  213 ARG   D NE  1 ? 
ATOM   597  C  CZ  . ARG   A 1 103 ? -43.541 -19.121 -5.102  1.000 50.128  0  213 ARG   D CZ  1 ? 
ATOM   598  N  NH1 . ARG   A 1 103 ? -43.750 -19.877 -4.036  1.000 54.848  0  213 ARG   D NH1 1 ? 
ATOM   599  N  NH2 . ARG   A 1 103 ? -44.419 -18.185 -5.427  1.000 51.230  0  213 ARG   D NH2 1 ? 
ATOM   600  N  N   . LEU   A 1 104 ? -36.486 -17.452 -7.044  1.000 34.951  0  214 LEU   D N   1 ? 
ATOM   601  C  CA  . LEU   A 1 104 ? -35.621 -16.291 -7.258  1.000 34.477  0  214 LEU   D CA  1 ? 
ATOM   602  C  C   . LEU   A 1 104 ? -35.016 -16.367 -8.663  1.000 31.975  0  214 LEU   D C   1 ? 
ATOM   603  O  O   . LEU   A 1 104 ? -34.970 -15.369 -9.379  1.000 29.373  0  214 LEU   D O   1 ? 
ATOM   604  C  CB  . LEU   A 1 104 ? -34.527 -16.213 -6.191  1.000 33.361  0  214 LEU   D CB  1 ? 
ATOM   605  C  CG  . LEU   A 1 104 ? -34.953 -15.698 -4.813  1.000 33.109  0  214 LEU   D CG  1 ? 
ATOM   606  C  CD1 . LEU   A 1 104 ? -33.807 -15.842 -3.834  1.000 35.228  0  214 LEU   D CD1 1 ? 
ATOM   607  C  CD2 . LEU   A 1 104 ? -35.426 -14.248 -4.869  1.000 34.135  0  214 LEU   D CD2 1 ? 
ATOM   608  N  N   . HIS   A 1 105 ? -34.593 -17.574 -9.055  1.000 31.607  0  215 HIS   D N   1 ? 
ATOM   609  C  CA  . HIS   A 1 105 ? -33.927 -17.792 -10.329 1.000 35.784  0  215 HIS   D CA  1 ? 
ATOM   610  C  C   . HIS   A 1 105 ? -34.888 -17.516 -11.496 1.000 41.132  0  215 HIS   D C   1 ? 
ATOM   611  O  O   . HIS   A 1 105 ? -34.454 -17.096 -12.565 1.000 33.892  0  215 HIS   D O   1 ? 
ATOM   612  C  CB  . HIS   A 1 105 ? -33.353 -19.214 -10.394 1.000 35.982  0  215 HIS   D CB  1 ? 
ATOM   613  C  CG  . HIS   A 1 105 ? -32.445 -19.445 -11.553 1.000 39.690  0  215 HIS   D CG  1 ? 
ATOM   614  N  ND1 . HIS   A 1 105 ? -32.898 -19.767 -12.815 1.000 35.387  0  215 HIS   D ND1 1 ? 
ATOM   615  C  CD2 . HIS   A 1 105 ? -31.108 -19.358 -11.649 1.000 40.104  0  215 HIS   D CD2 1 ? 
ATOM   616  C  CE1 . HIS   A 1 105 ? -31.861 -19.898 -13.628 1.000 40.243  0  215 HIS   D CE1 1 ? 
ATOM   617  N  NE2 . HIS   A 1 105 ? -30.764 -19.648 -12.941 1.000 39.014  0  215 HIS   D NE2 1 ? 
ATOM   618  N  N   . SER   A 1 106 ? -36.191 -17.784 -11.287 1.000 41.652  0  216 SER   D N   1 ? 
ATOM   619  C  CA  . SER   A 1 106 ? -37.193 -17.618 -12.338 1.000 39.752  0  216 SER   D CA  1 ? 
ATOM   620  C  C   . SER   A 1 106 ? -38.042 -16.368 -12.090 1.000 41.437  0  216 SER   D C   1 ? 
ATOM   621  O  O   . SER   A 1 106 ? -39.015 -16.139 -12.802 1.000 48.318  0  216 SER   D O   1 ? 
ATOM   622  C  CB  . SER   A 1 106 ? -38.071 -18.844 -12.449 1.000 38.586  0  216 SER   D CB  1 ? 
ATOM   623  O  OG  . SER   A 1 106 ? -38.900 -18.987 -11.301 1.000 37.300  0  216 SER   D OG  1 ? 
ATOM   624  N  N   . ASP   A 1 107 ? -37.654 -15.557 -11.091 1.000 42.138  0  217 ASP   D N   1 ? 
ATOM   625  C  CA  . ASP   A 1 107 ? -38.423 -14.376 -10.718 1.000 44.769  0  217 ASP   D CA  1 ? 
ATOM   626  C  C   . ASP   A 1 107 ? -38.378 -13.362 -11.859 1.000 48.668  0  217 ASP   D C   1 ? 
ATOM   627  O  O   . ASP   A 1 107 ? -37.357 -13.213 -12.526 1.000 54.917  0  217 ASP   D O   1 ? 
ATOM   628  C  CB  . ASP   A 1 107 ? -37.919 -13.760 -9.418  1.000 43.871  0  217 ASP   D CB  1 ? 
ATOM   629  C  CG  . ASP   A 1 107 ? -38.838 -12.723 -8.778  1.000 45.878  0  217 ASP   D CG  1 ? 
ATOM   630  O  OD1 . ASP   A 1 107 ? -39.948 -12.503 -9.315  1.000 50.583  0  217 ASP   D OD1 1 ? 
ATOM   631  O  OD2 . ASP   A 1 107 ? -38.445 -12.153 -7.737  1.000 42.974  0  217 ASP   D OD2 1 ? 
ATOM   632  N  N   . LYS   A 1 108 ? -39.506 -12.675 -12.069 1.000 65.242  0  218 LYS   D N   1 ? 
ATOM   633  C  CA  . LYS   A 1 108 ? -39.626 -11.658 -13.103 1.000 63.924  0  218 LYS   D CA  1 ? 
ATOM   634  C  C   . LYS   A 1 108 ? -40.424 -10.487 -12.540 1.000 53.670  0  218 LYS   D C   1 ? 
ATOM   635  O  O   . LYS   A 1 108 ? -41.484 -10.684 -11.945 1.000 64.744  0  218 LYS   D O   1 ? 
ATOM   636  C  CB  . LYS   A 1 108 ? -40.279 -12.262 -14.354 1.000 66.753  0  218 LYS   D CB  1 ? 
ATOM   637  C  CG  . LYS   A 1 108 ? -39.467 -13.370 -15.019 1.000 77.846  0  218 LYS   D CG  1 ? 
ATOM   638  C  CD  . LYS   A 1 108 ? -40.236 -14.203 -16.034 1.000 83.121  0  218 LYS   D CD  1 ? 
ATOM   639  C  CE  . LYS   A 1 108 ? -39.470 -15.424 -16.463 1.000 88.447  0  218 LYS   D CE  1 ? 
ATOM   640  N  NZ  . LYS   A 1 108 ? -38.215 -15.082 -17.141 1.000 94.941  0  218 LYS   D NZ  1 ? 
ATOM   641  N  N   . GLY   A 1 109 ? -39.858 -9.279  -12.659 1.000 43.508  0  219 GLY   D N   1 ? 
ATOM   642  C  CA  . GLY   A 1 109 ? -40.441 -8.089  -12.061 1.000 46.672  0  219 GLY   D CA  1 ? 
ATOM   643  C  C   . GLY   A 1 109 ? -40.172 -8.026  -10.553 1.000 47.239  0  219 GLY   D C   1 ? 
ATOM   644  O  O   . GLY   A 1 109 ? -40.631 -7.107  -9.879  1.000 62.105  0  219 GLY   D O   1 ? 
ATOM   645  N  N   . GLY   A 1 110 ? -39.396 -8.999  -10.043 1.000 46.493  0  220 GLY   D N   1 ? 
ATOM   646  C  CA  . GLY   A 1 110 ? -39.072 -9.075  -8.627  1.000 39.903  0  220 GLY   D CA  1 ? 
ATOM   647  C  C   . GLY   A 1 110 ? -40.307 -9.365  -7.772  1.000 40.774  0  220 GLY   D C   1 ? 
ATOM   648  O  O   . GLY   A 1 110 ? -40.341 -9.006  -6.598  1.000 52.153  0  220 GLY   D O   1 ? 
ATOM   649  N  N   . SER   A 1 111 ? -41.295 -10.065 -8.356  1.000 42.046  0  221 SER   D N   1 ? 
ATOM   650  C  CA  . SER   A 1 111 ? -42.572 -10.298 -7.688  1.000 42.118  0  221 SER   D CA  1 ? 
ATOM   651  C  C   . SER   A 1 111 ? -42.374 -11.223 -6.488  1.000 37.077  0  221 SER   D C   1 ? 
ATOM   652  O  O   . SER   A 1 111 ? -42.859 -10.938 -5.401  1.000 42.352  0  221 SER   D O   1 ? 
ATOM   653  C  CB  . SER   A 1 111 ? -43.616 -10.854 -8.647  1.000 45.166  0  221 SER   D CB  1 ? 
ATOM   654  O  OG  . SER   A 1 111 ? -43.378 -12.225 -8.942  1.000 55.506  0  221 SER   D OG  1 ? 
ATOM   655  N  N   . PHE   A 1 112 ? -41.651 -12.329 -6.701  1.000 36.754  0  222 PHE   D N   1 ? 
ATOM   656  C  CA  . PHE   A 1 112 ? -41.395 -13.293 -5.641  1.000 43.044  0  222 PHE   D CA  1 ? 
ATOM   657  C  C   . PHE   A 1 112 ? -40.444 -12.682 -4.605  1.000 40.381  0  222 PHE   D C   1 ? 
ATOM   658  O  O   . PHE   A 1 112 ? -40.625 -12.874 -3.407  1.000 41.388  0  222 PHE   D O   1 ? 
ATOM   659  C  CB  . PHE   A 1 112 ? -40.830 -14.594 -6.209  1.000 38.696  0  222 PHE   D CB  1 ? 
ATOM   660  C  CG  . PHE   A 1 112 ? -40.441 -15.602 -5.141  1.000 38.993  0  222 PHE   D CG  1 ? 
ATOM   661  C  CD1 . PHE   A 1 112 ? -41.395 -16.440 -4.568  1.000 43.428  0  222 PHE   D CD1 1 ? 
ATOM   662  C  CD2 . PHE   A 1 112 ? -39.129 -15.684 -4.680  1.000 35.397  0  222 PHE   D CD2 1 ? 
ATOM   663  C  CE1 . PHE   A 1 112 ? -41.041 -17.343 -3.578  1.000 44.379  0  222 PHE   D CE1 1 ? 
ATOM   664  C  CE2 . PHE   A 1 112 ? -38.781 -16.590 -3.691  1.000 37.881  0  222 PHE   D CE2 1 ? 
ATOM   665  C  CZ  . PHE   A 1 112 ? -39.735 -17.418 -3.143  1.000 47.038  0  222 PHE   D CZ  1 ? 
ATOM   666  N  N   . GLU   A 1 113 ? -39.409 -11.988 -5.089  1.000 38.739  0  223 GLU   D N   1 ? 
ATOM   667  C  CA  . GLU   A 1 113 ? -38.448 -11.313 -4.225  1.000 40.895  0  223 GLU   D CA  1 ? 
ATOM   668  C  C   . GLU   A 1 113 ? -39.186 -10.362 -3.271  1.000 39.071  0  223 GLU   D C   1 ? 
ATOM   669  O  O   . GLU   A 1 113 ? -38.810 -10.234 -2.108  1.000 37.401  0  223 GLU   D O   1 ? 
ATOM   670  C  CB  . GLU   A 1 113 ? -37.419 -10.577 -5.092  1.000 36.183  0  223 GLU   D CB  1 ? 
ATOM   671  C  CG  . GLU   A 1 113 ? -36.439 -9.719  -4.300  1.000 37.726  0  223 GLU   D CG  1 ? 
ATOM   672  C  CD  . GLU   A 1 113 ? -35.532 -8.859  -5.169  1.000 48.654  0  223 GLU   D CD  1 ? 
ATOM   673  O  OE1 . GLU   A 1 113 ? -35.430 -9.143  -6.380  1.000 49.589  0  223 GLU   D OE1 1 ? 
ATOM   674  O  OE2 . GLU   A 1 113 ? -35.021 -7.838  -4.656  1.000 48.745  0  223 GLU   D OE2 1 ? 
ATOM   675  N  N   . ALA   A 1 114 ? -40.227 -9.689  -3.789  1.000 39.502  0  224 ALA   D N   1 ? 
ATOM   676  C  CA  . ALA   A 1 114 ? -41.029 -8.762  -2.997  1.000 39.398  0  224 ALA   D CA  1 ? 
ATOM   677  C  C   . ALA   A 1 114 ? -41.835 -9.527  -1.941  1.000 40.323  0  224 ALA   D C   1 ? 
ATOM   678  O  O   . ALA   A 1 114 ? -41.923 -9.101  -0.793  1.000 41.068  0  224 ALA   D O   1 ? 
ATOM   679  C  CB  . ALA   A 1 114 ? -41.933 -7.956  -3.907  1.000 39.229  0  224 ALA   D CB  1 ? 
ATOM   680  N  N   . ALA   A 1 115 ? -42.431 -10.653 -2.350  1.000 40.320  0  225 ALA   D N   1 ? 
ATOM   681  C  CA  . ALA   A 1 115 ? -43.199 -11.490 -1.441  1.000 44.719  0  225 ALA   D CA  1 ? 
ATOM   682  C  C   . ALA   A 1 115 ? -42.302 -11.991 -0.305  1.000 46.210  0  225 ALA   D C   1 ? 
ATOM   683  O  O   . ALA   A 1 115 ? -42.694 -11.956 0.860   1.000 44.724  0  225 ALA   D O   1 ? 
ATOM   684  C  CB  . ALA   A 1 115 ? -43.823 -12.639 -2.203  1.000 43.958  0  225 ALA   D CB  1 ? 
ATOM   685  N  N   . LEU   A 1 116 ? -41.085 -12.433 -0.664  1.000 42.581  0  226 LEU   D N   1 ? 
ATOM   686  C  CA  . LEU   A 1 116 ? -40.137 -12.981 0.298   1.000 42.985  0  226 LEU   D CA  1 ? 
ATOM   687  C  C   . LEU   A 1 116 ? -39.807 -11.924 1.357   1.000 41.042  0  226 LEU   D C   1 ? 
ATOM   688  O  O   . LEU   A 1 116 ? -39.744 -12.234 2.545   1.000 36.972  0  226 LEU   D O   1 ? 
ATOM   689  C  CB  . LEU   A 1 116 ? -38.883 -13.456 -0.439  1.000 46.370  0  226 LEU   D CB  1 ? 
ATOM   690  C  CG  . LEU   A 1 116 ? -37.844 -14.209 0.401   1.000 50.876  0  226 LEU   D CG  1 ? 
ATOM   691  C  CD1 . LEU   A 1 116 ? -38.397 -15.529 0.936   1.000 50.085  0  226 LEU   D CD1 1 ? 
ATOM   692  C  CD2 . LEU   A 1 116 ? -36.583 -14.451 -0.409  1.000 54.891  0  226 LEU   D CD2 1 ? 
ATOM   693  N  N   . TRP   A 1 117 ? -39.620 -10.675 0.908   1.000 42.473  0  227 TRP   D N   1 ? 
ATOM   694  C  CA  . TRP   A 1 117 ? -39.307 -9.561  1.793   1.000 39.138  0  227 TRP   D CA  1 ? 
ATOM   695  C  C   . TRP   A 1 117 ? -40.428 -9.356  2.808   1.000 44.796  0  227 TRP   D C   1 ? 
ATOM   696  O  O   . TRP   A 1 117 ? -40.165 -9.186  3.996   1.000 46.091  0  227 TRP   D O   1 ? 
ATOM   697  C  CB  . TRP   A 1 117 ? -39.067 -8.284  0.971   1.000 38.933  0  227 TRP   D CB  1 ? 
ATOM   698  C  CG  . TRP   A 1 117 ? -38.813 -7.048  1.797   1.000 42.075  0  227 TRP   D CG  1 ? 
ATOM   699  C  CD1 . TRP   A 1 117 ? -39.673 -6.009  2.012   1.000 42.935  0  227 TRP   D CD1 1 ? 
ATOM   700  C  CD2 . TRP   A 1 117 ? -37.610 -6.729  2.529   1.000 39.774  0  227 TRP   D CD2 1 ? 
ATOM   701  N  NE1 . TRP   A 1 117 ? -39.085 -5.060  2.809   1.000 42.395  0  227 TRP   D NE1 1 ? 
ATOM   702  C  CE2 . TRP   A 1 117 ? -37.823 -5.475  3.147   1.000 41.367  0  227 TRP   D CE2 1 ? 
ATOM   703  C  CE3 . TRP   A 1 117 ? -36.380 -7.371  2.714   1.000 42.934  0  227 TRP   D CE3 1 ? 
ATOM   704  C  CZ2 . TRP   A 1 117 ? -36.850 -4.859  3.934   1.000 45.961  0  227 TRP   D CZ2 1 ? 
ATOM   705  C  CZ3 . TRP   A 1 117 ? -35.418 -6.760  3.492   1.000 44.680  0  227 TRP   D CZ3 1 ? 
ATOM   706  C  CH2 . TRP   A 1 117 ? -35.650 -5.519  4.090   1.000 46.274  0  227 TRP   D CH2 1 ? 
ATOM   707  N  N   . GLN   A 1 118 ? -41.678 -9.383  2.322   1.000 53.488  0  228 GLN   D N   1 ? 
ATOM   708  C  CA  . GLN   A 1 118 ? -42.834 -9.048  3.141   1.000 55.575  0  228 GLN   D CA  1 ? 
ATOM   709  C  C   . GLN   A 1 118 ? -43.118 -10.173 4.141   1.000 46.228  0  228 GLN   D C   1 ? 
ATOM   710  O  O   . GLN   A 1 118 ? -43.386 -9.912  5.311   1.000 51.764  0  228 GLN   D O   1 ? 
ATOM   711  C  CB  . GLN   A 1 118 ? -44.066 -8.812  2.266   1.000 60.093  0  228 GLN   D CB  1 ? 
ATOM   712  C  CG  . GLN   A 1 118 ? -45.257 -8.228  3.021   1.000 70.654  0  228 GLN   D CG  1 ? 
ATOM   713  C  CD  . GLN   A 1 118 ? -46.589 -8.572  2.389   1.000 82.669  0  228 GLN   D CD  1 ? 
ATOM   714  O  OE1 . GLN   A 1 118 ? -46.888 -8.178  1.255   1.000 84.462  0  228 GLN   D OE1 1 ? 
ATOM   715  N  NE2 . GLN   A 1 118 ? -47.408 -9.318  3.121   1.000 81.249  0  228 GLN   D NE2 1 ? 
ATOM   716  N  N   . GLN   A 1 119 ? -43.062 -11.420 3.663   1.000 45.486  0  229 GLN   D N   1 ? 
ATOM   717  C  CA  . GLN   A 1 119 ? -43.524 -12.564 4.436   1.000 49.518  0  229 GLN   D CA  1 ? 
ATOM   718  C  C   . GLN   A 1 119 ? -42.538 -12.894 5.565   1.000 43.792  0  229 GLN   D C   1 ? 
ATOM   719  O  O   . GLN   A 1 119 ? -42.953 -13.295 6.650   1.000 44.877  0  229 GLN   D O   1 ? 
ATOM   720  C  CB  . GLN   A 1 119 ? -43.747 -13.757 3.510   1.000 43.989  0  229 GLN   D CB  1 ? 
ATOM   721  C  CG  . GLN   A 1 119 ? -44.277 -14.995 4.217   1.000 41.626  0  229 GLN   D CG  1 ? 
ATOM   722  C  CD  . GLN   A 1 119 ? -44.543 -16.141 3.271   1.000 37.728  0  229 GLN   D CD  1 ? 
ATOM   723  O  OE1 . GLN   A 1 119 ? -45.285 -16.005 2.294   1.000 44.161  0  229 GLN   D OE1 1 ? 
ATOM   724  N  NE2 . GLN   A 1 119 ? -43.909 -17.275 3.532   1.000 39.133  0  229 GLN   D NE2 1 ? 
ATOM   725  N  N   . TRP   A 1 120 ? -41.236 -12.747 5.294   1.000 42.990  0  230 TRP   D N   1 ? 
ATOM   726  C  CA  . TRP   A 1 120 ? -40.208 -13.140 6.250   1.000 46.316  0  230 TRP   D CA  1 ? 
ATOM   727  C  C   . TRP   A 1 120 ? -39.871 -11.983 7.185   1.000 42.363  0  230 TRP   D C   1 ? 
ATOM   728  O  O   . TRP   A 1 120 ? -39.958 -10.817 6.807   1.000 50.239  0  230 TRP   D O   1 ? 
ATOM   729  C  CB  . TRP   A 1 120 ? -38.954 -13.642 5.521   1.000 47.872  0  230 TRP   D CB  1 ? 
ATOM   730  C  CG  . TRP   A 1 120 ? -39.080 -15.038 4.969   1.000 48.556  0  230 TRP   D CG  1 ? 
ATOM   731  C  CD1 . TRP   A 1 120 ? -40.229 -15.750 4.770   1.000 49.186  0  230 TRP   D CD1 1 ? 
ATOM   732  C  CD2 . TRP   A 1 120 ? -38.005 -15.869 4.482   1.000 50.483  0  230 TRP   D CD2 1 ? 
ATOM   733  N  NE1 . TRP   A 1 120 ? -39.941 -16.978 4.236   1.000 47.220  0  230 TRP   D NE1 1 ? 
ATOM   734  C  CE2 . TRP   A 1 120 ? -38.588 -17.075 4.035   1.000 43.808  0  230 TRP   D CE2 1 ? 
ATOM   735  C  CE3 . TRP   A 1 120 ? -36.614 -15.712 4.381   1.000 52.390  0  230 TRP   D CE3 1 ? 
ATOM   736  C  CZ2 . TRP   A 1 120 ? -37.827 -18.114 3.500   1.000 45.842  0  230 TRP   D CZ2 1 ? 
ATOM   737  C  CZ3 . TRP   A 1 120 ? -35.865 -16.738 3.844   1.000 49.936  0  230 TRP   D CZ3 1 ? 
ATOM   738  C  CH2 . TRP   A 1 120 ? -36.465 -17.923 3.412   1.000 45.575  0  230 TRP   D CH2 1 ? 
ATOM   739  N  N   . ASP   A 1 121 ? -39.470 -12.337 8.409   1.000 41.581  0  231 ASP   D N   1 ? 
ATOM   740  C  CA  . ASP   A 1 121 ? -39.016 -11.371 9.391   1.000 47.102  0  231 ASP   D CA  1 ? 
ATOM   741  C  C   . ASP   A 1 121 ? -37.563 -11.008 9.087   1.000 46.335  0  231 ASP   D C   1 ? 
ATOM   742  O  O   . ASP   A 1 121 ? -36.897 -11.689 8.306   1.000 43.522  0  231 ASP   D O   1 ? 
ATOM   743  C  CB  . ASP   A 1 121 ? -39.225 -11.885 10.810  1.000 50.965  0  231 ASP   D CB  1 ? 
ATOM   744  C  CG  . ASP   A 1 121 ? -38.659 -13.267 11.096  1.000 70.009  0  231 ASP   D CG  1 ? 
ATOM   745  O  OD1 . ASP   A 1 121 ? -39.113 -14.234 10.442  1.000 80.627  0  231 ASP   D OD1 1 ? 
ATOM   746  O  OD2 . ASP   A 1 121 ? -37.775 -13.367 11.965  1.000 78.509  0  231 ASP   D OD2 1 ? 
ATOM   747  N  N   . ARG   A 1 122 ? -37.073 -9.971  9.770   1.000 46.556  0  232 ARG   D N   1 ? 
ATOM   748  C  CA  . ARG   A 1 122 ? -35.812 -9.333  9.432   1.000 45.286  0  232 ARG   D CA  1 ? 
ATOM   749  C  C   . ARG   A 1 122 ? -34.641 -10.299 9.654   1.000 47.596  0  232 ARG   D C   1 ? 
ATOM   750  O  O   . ARG   A 1 122 ? -33.780 -10.433 8.787   1.000 50.827  0  232 ARG   D O   1 ? 
ATOM   751  C  CB  . ARG   A 1 122 ? -35.678 -8.038  10.243  1.000 42.936  0  232 ARG   D CB  1 ? 
ATOM   752  C  CG  . ARG   A 1 122 ? -34.503 -7.166  9.841   1.000 52.252  0  232 ARG   D CG  1 ? 
ATOM   753  C  CD  . ARG   A 1 122 ? -34.621 -5.754  10.393  1.000 55.506  0  232 ARG   D CD  1 ? 
ATOM   754  N  NE  . ARG   A 1 122 ? -33.420 -4.956  10.112  1.000 56.788  0  232 ARG   D NE  1 ? 
ATOM   755  C  CZ  . ARG   A 1 122 ? -32.218 -5.166  10.656  1.000 60.768  0  232 ARG   D CZ  1 ? 
ATOM   756  N  NH1 . ARG   A 1 122 ? -32.062 -6.080  11.603  1.000 61.926  0  232 ARG   D NH1 1 ? 
ATOM   757  N  NH2 . ARG   A 1 122 ? -31.188 -4.418  10.294  1.000 58.373  0  232 ARG   D NH2 1 ? 
ATOM   758  N  N   . GLN   A 1 123 ? -34.634 -10.984 10.806  1.000 45.029  0  233 GLN   D N   1 ? 
ATOM   759  C  CA  . GLN   A 1 123 ? -33.518 -11.851 11.180  1.000 53.279  0  233 GLN   D CA  1 ? 
ATOM   760  C  C   . GLN   A 1 123 ? -33.387 -13.009 10.185  1.000 46.446  0  233 GLN   D C   1 ? 
ATOM   761  O  O   . GLN   A 1 123 ? -32.277 -13.389 9.823   1.000 42.663  0  233 GLN   D O   1 ? 
ATOM   762  C  CB  . GLN   A 1 123 ? -33.640 -12.371 12.618  1.000 60.881  0  233 GLN   D CB  1 ? 
ATOM   763  C  CG  . GLN   A 1 123 ? -34.971 -13.046 12.938  1.000 80.614  0  233 GLN   D CG  1 ? 
ATOM   764  C  CD  . GLN   A 1 123 ? -34.951 -13.823 14.238  1.000 94.560  0  233 GLN   D CD  1 ? 
ATOM   765  O  OE1 . GLN   A 1 123 ? -34.588 -13.298 15.297  1.000 96.646  0  233 GLN   D OE1 1 ? 
ATOM   766  N  NE2 . GLN   A 1 123 ? -35.330 -15.093 14.168  1.000 87.635  0  233 GLN   D NE2 1 ? 
ATOM   767  N  N   . SER   A 1 124 ? -34.528 -13.554 9.742   1.000 46.235  0  234 SER   D N   1 ? 
ATOM   768  C  CA  . SER   A 1 124 ? -34.534 -14.698 8.840   1.000 43.018  0  234 SER   D CA  1 ? 
ATOM   769  C  C   . SER   A 1 124 ? -33.907 -14.322 7.498   1.000 39.177  0  234 SER   D C   1 ? 
ATOM   770  O  O   . SER   A 1 124 ? -33.195 -15.124 6.899   1.000 36.852  0  234 SER   D O   1 ? 
ATOM   771  C  CB  . SER   A 1 124 ? -35.924 -15.242 8.661   1.000 42.414  0  234 SER   D CB  1 ? 
ATOM   772  O  OG  . SER   A 1 124 ? -36.376 -15.869 9.851   1.000 49.756  0  234 SER   D OG  1 ? 
ATOM   773  N  N   . LEU   A 1 125 ? -34.204 -13.102 7.027   1.000 33.353  0  235 LEU   D N   1 ? 
ATOM   774  C  CA  . LEU   A 1 125 ? -33.665 -12.603 5.773   1.000 32.574  0  235 LEU   D CA  1 ? 
ATOM   775  C  C   . LEU   A 1 125 ? -32.160 -12.375 5.911   1.000 30.819  0  235 LEU   D C   1 ? 
ATOM   776  O  O   . LEU   A 1 125 ? -31.407 -12.652 4.983   1.000 29.871  0  235 LEU   D O   1 ? 
ATOM   777  C  CB  . LEU   A 1 125 ? -34.399 -11.326 5.365   1.000 36.431  0  235 LEU   D CB  1 ? 
ATOM   778  C  CG  . LEU   A 1 125 ? -35.843 -11.510 4.886   1.000 47.207  0  235 LEU   D CG  1 ? 
ATOM   779  C  CD1 . LEU   A 1 125 ? -36.599 -10.189 4.876   1.000 48.420  0  235 LEU   D CD1 1 ? 
ATOM   780  C  CD2 . LEU   A 1 125 ? -35.867 -12.144 3.505   1.000 51.329  0  235 LEU   D CD2 1 ? 
ATOM   781  N  N   . ILE   A 1 126 ? -31.737 -11.878 7.087   1.000 30.272  0  236 ILE   D N   1 ? 
ATOM   782  C  CA  . ILE   A 1 126 ? -30.329 -11.598 7.359   1.000 35.847  0  236 ILE   D CA  1 ? 
ATOM   783  C  C   . ILE   A 1 126 ? -29.510 -12.884 7.217   1.000 38.535  0  236 ILE   D C   1 ? 
ATOM   784  O  O   . ILE   A 1 126 ? -28.508 -12.908 6.504   1.000 44.698  0  236 ILE   D O   1 ? 
ATOM   785  C  CB  . ILE   A 1 126 ? -30.158 -10.952 8.751   1.000 37.628  0  236 ILE   D CB  1 ? 
ATOM   786  C  CG1 . ILE   A 1 126 ? -30.601 -9.485  8.735   1.000 38.739  0  236 ILE   D CG1 1 ? 
ATOM   787  C  CG2 . ILE   A 1 126 ? -28.717 -11.096 9.257   1.000 41.793  0  236 ILE   D CG2 1 ? 
ATOM   788  C  CD1 . ILE   A 1 126 ? -30.748 -8.860  10.111  1.000 40.865  0  236 ILE   D CD1 1 ? 
ATOM   789  N  N   . MET   A 1 127 ? -29.949 -13.944 7.903   1.000 40.376  0  237 MET   D N   1 ? 
ATOM   790  C  CA  . MET   A 1 127 ? -29.226 -15.209 7.918   1.000 45.459  0  237 MET   D CA  1 ? 
ATOM   791  C  C   . MET   A 1 127 ? -29.206 -15.838 6.523   1.000 41.818  0  237 MET   D C   1 ? 
ATOM   792  O  O   . MET   A 1 127 ? -28.200 -16.426 6.124   1.000 40.152  0  237 MET   D O   1 ? 
ATOM   793  C  CB  . MET   A 1 127 ? -29.835 -16.178 8.939   1.000 54.841  0  237 MET   D CB  1 ? 
ATOM   794  C  CG  . MET   A 1 127 ? -29.169 -16.114 10.307  1.000 61.872  0  237 MET   D CG  1 ? 
ATOM   795  S  SD  . MET   A 1 127 ? -30.157 -16.857 11.618  1.000 66.673  0  237 MET   D SD  1 ? 
ATOM   796  C  CE  . MET   A 1 127 ? -31.225 -15.471 12.031  1.000 85.903  0  237 MET   D CE  1 ? 
ATOM   797  N  N   . PHE   A 1 128 ? -30.316 -15.701 5.783   1.000 38.895  0  238 PHE   D N   1 ? 
ATOM   798  C  CA  . PHE   A 1 128 ? -30.415 -16.267 4.445   1.000 39.423  0  238 PHE   D CA  1 ? 
ATOM   799  C  C   . PHE   A 1 128 ? -29.447 -15.536 3.512   1.000 33.983  0  238 PHE   D C   1 ? 
ATOM   800  O  O   . PHE   A 1 128 ? -28.773 -16.163 2.699   1.000 29.351  0  238 PHE   D O   1 ? 
ATOM   801  C  CB  . PHE   A 1 128 ? -31.847 -16.190 3.904   1.000 37.748  0  238 PHE   D CB  1 ? 
ATOM   802  C  CG  . PHE   A 1 128 ? -32.069 -17.005 2.635   1.000 40.115  0  238 PHE   D CG  1 ? 
ATOM   803  C  CD1 . PHE   A 1 128 ? -31.738 -16.489 1.383   1.000 38.867  0  238 PHE   D CD1 1 ? 
ATOM   804  C  CD2 . PHE   A 1 128 ? -32.590 -18.296 2.698   1.000 43.912  0  238 PHE   D CD2 1 ? 
ATOM   805  C  CE1 . PHE   A 1 128 ? -31.931 -17.240 0.233   1.000 37.498  0  238 PHE   D CE1 1 ? 
ATOM   806  C  CE2 . PHE   A 1 128 ? -32.783 -19.039 1.543   1.000 44.152  0  238 PHE   D CE2 1 ? 
ATOM   807  C  CZ  . PHE   A 1 128 ? -32.451 -18.511 0.316   1.000 43.132  0  238 PHE   D CZ  1 ? 
ATOM   808  N  N   . ILE   A 1 129 ? -29.415 -14.201 3.625   1.000 32.109  0  239 ILE   D N   1 ? 
ATOM   809  C  CA  . ILE   A 1 129 ? -28.586 -13.365 2.768   1.000 33.280  0  239 ILE   D CA  1 ? 
ATOM   810  C  C   . ILE   A 1 129 ? -27.110 -13.645 3.061   1.000 35.074  0  239 ILE   D C   1 ? 
ATOM   811  O  O   . ILE   A 1 129 ? -26.322 -13.853 2.137   1.000 32.031  0  239 ILE   D O   1 ? 
ATOM   812  C  CB  . ILE   A 1 129 ? -28.946 -11.874 2.949   1.000 33.066  0  239 ILE   D CB  1 ? 
ATOM   813  C  CG1 . ILE   A 1 129 ? -30.313 -11.551 2.317   1.000 33.076  0  239 ILE   D CG1 1 ? 
ATOM   814  C  CG2 . ILE   A 1 129 ? -27.840 -10.964 2.394   1.000 29.435  0  239 ILE   D CG2 1 ? 
ATOM   815  C  CD1 . ILE   A 1 129 ? -30.896 -10.213 2.738   1.000 35.576  0  239 ILE   D CD1 1 ? 
ATOM   816  N  N   . THR   A 1 130 ? -26.749 -13.645 4.352   1.000 29.125  0  240 THR   D N   1 ? 
ATOM   817  C  CA  . THR   A 1 130 ? -25.367 -13.863 4.767   1.000 36.737  0  240 THR   D CA  1 ? 
ATOM   818  C  C   . THR   A 1 130 ? -24.884 -15.215 4.240   1.000 34.668  0  240 THR   D C   1 ? 
ATOM   819  O  O   . THR   A 1 130 ? -23.767 -15.326 3.741   1.000 33.681  0  240 THR   D O   1 ? 
ATOM   820  C  CB  . THR   A 1 130 ? -25.262 -13.775 6.291   1.000 39.664  0  240 THR   D CB  1 ? 
ATOM   821  O  OG1 . THR   A 1 130 ? -25.558 -12.416 6.598   1.000 42.929  0  240 THR   D OG1 1 ? 
ATOM   822  C  CG2 . THR   A 1 130 ? -23.878 -14.125 6.809   1.000 40.928  0  240 THR   D CG2 1 ? 
ATOM   823  N  N   . ALA   A 1 131 ? -25.745 -16.232 4.348   1.000 36.979  0  241 ALA   D N   1 ? 
ATOM   824  C  CA  . ALA   A 1 131 ? -25.416 -17.575 3.891   1.000 36.051  0  241 ALA   D CA  1 ? 
ATOM   825  C  C   . ALA   A 1 131 ? -25.108 -17.559 2.394   1.000 31.806  0  241 ALA   D C   1 ? 
ATOM   826  O  O   . ALA   A 1 131 ? -24.017 -17.935 1.983   1.000 34.676  0  241 ALA   D O   1 ? 
ATOM   827  C  CB  . ALA   A 1 131 ? -26.553 -18.528 4.215   1.000 37.501  0  241 ALA   D CB  1 ? 
ATOM   828  N  N   . PHE   A 1 132 ? -26.056 -17.041 1.602   1.000 32.793  0  242 PHE   D N   1 ? 
ATOM   829  C  CA  . PHE   A 1 132 ? -25.960 -17.077 0.149   1.000 36.585  0  242 PHE   D CA  1 ? 
ATOM   830  C  C   . PHE   A 1 132 ? -24.682 -16.380 -0.324  1.000 34.343  0  242 PHE   D C   1 ? 
ATOM   831  O  O   . PHE   A 1 132 ? -23.962 -16.920 -1.154  1.000 36.890  0  242 PHE   D O   1 ? 
ATOM   832  C  CB  . PHE   A 1 132 ? -27.185 -16.433 -0.506  1.000 35.360  0  242 PHE   D CB  1 ? 
ATOM   833  C  CG  . PHE   A 1 132 ? -27.009 -16.197 -1.998  1.000 36.761  0  242 PHE   D CG  1 ? 
ATOM   834  C  CD1 . PHE   A 1 132 ? -27.175 -17.234 -2.910  1.000 36.786  0  242 PHE   D CD1 1 ? 
ATOM   835  C  CD2 . PHE   A 1 132 ? -26.601 -14.957 -2.480  1.000 40.463  0  242 PHE   D CD2 1 ? 
ATOM   836  C  CE1 . PHE   A 1 132 ? -26.971 -17.024 -4.266  1.000 40.346  0  242 PHE   D CE1 1 ? 
ATOM   837  C  CE2 . PHE   A 1 132 ? -26.399 -14.755 -3.835  1.000 37.238  0  242 PHE   D CE2 1 ? 
ATOM   838  C  CZ  . PHE   A 1 132 ? -26.585 -15.787 -4.725  1.000 35.740  0  242 PHE   D CZ  1 ? 
ATOM   839  N  N   . LEU   A 1 133 ? -24.444 -15.157 0.173   1.000 39.692  0  243 LEU   D N   1 ? 
ATOM   840  C  CA  . LEU   A 1 133 ? -23.322 -14.336 -0.282  1.000 41.746  0  243 LEU   D CA  1 ? 
ATOM   841  C  C   . LEU   A 1 133 ? -22.002 -15.084 -0.080  1.000 37.030  0  243 LEU   D C   1 ? 
ATOM   842  O  O   . LEU   A 1 133 ? -21.094 -14.970 -0.899  1.000 44.534  0  243 LEU   D O   1 ? 
ATOM   843  C  CB  . LEU   A 1 133 ? -23.316 -12.990 0.446   1.000 38.790  0  243 LEU   D CB  1 ? 
ATOM   844  C  CG  . LEU   A 1 133 ? -24.471 -12.036 0.122   1.000 35.994  0  243 LEU   D CG  1 ? 
ATOM   845  C  CD1 . LEU   A 1 133 ? -24.390 -10.798 0.996   1.000 41.554  0  243 LEU   D CD1 1 ? 
ATOM   846  C  CD2 . LEU   A 1 133 ? -24.488 -11.646 -1.343  1.000 39.538  0  243 LEU   D CD2 1 ? 
ATOM   847  N  N   . ASN   A 1 134 ? -21.900 -15.831 1.022   1.000 35.619  0  244 ASN   D N   1 ? 
ATOM   848  C  CA  . ASN   A 1 134 ? -20.704 -16.607 1.314   1.000 41.398  0  244 ASN   D CA  1 ? 
ATOM   849  C  C   . ASN   A 1 134 ? -20.617 -17.809 0.374   1.000 42.567  0  244 ASN   D C   1 ? 
ATOM   850  O  O   . ASN   A 1 134 ? -19.545 -18.111 -0.142  1.000 54.446  0  244 ASN   D O   1 ? 
ATOM   851  C  CB  . ASN   A 1 134 ? -20.651 -17.019 2.779   1.000 40.754  0  244 ASN   D CB  1 ? 
ATOM   852  C  CG  . ASN   A 1 134 ? -20.185 -15.886 3.663   1.000 36.938  0  244 ASN   D CG  1 ? 
ATOM   853  O  OD1 . ASN   A 1 134 ? -18.997 -15.541 3.654   1.000 41.366  0  244 ASN   D OD1 1 ? 
ATOM   854  N  ND2 . ASN   A 1 134 ? -21.088 -15.311 4.443   1.000 37.306  0  244 ASN   D ND2 1 ? 
ATOM   855  N  N   . ILE   A 1 135 ? -21.762 -18.466 0.135   1.000 42.204  0  245 ILE   D N   1 ? 
ATOM   856  C  CA  . ILE   A 1 135 ? -21.807 -19.672 -0.688  1.000 45.171  0  245 ILE   D CA  1 ? 
ATOM   857  C  C   . ILE   A 1 135 ? -21.529 -19.305 -2.146  1.000 40.515  0  245 ILE   D C   1 ? 
ATOM   858  O  O   . ILE   A 1 135 ? -20.737 -19.966 -2.810  1.000 38.102  0  245 ILE   D O   1 ? 
ATOM   859  C  CB  . ILE   A 1 135 ? -23.163 -20.402 -0.539  1.000 47.808  0  245 ILE   D CB  1 ? 
ATOM   860  C  CG1 . ILE   A 1 135 ? -23.484 -20.733 0.922   1.000 48.964  0  245 ILE   D CG1 1 ? 
ATOM   861  C  CG2 . ILE   A 1 135 ? -23.212 -21.651 -1.416  1.000 55.093  0  245 ILE   D CG2 1 ? 
ATOM   862  C  CD1 . ILE   A 1 135 ? -22.367 -21.446 1.659   1.000 51.335  0  245 ILE   D CD1 1 ? 
ATOM   863  N  N   . ALA   A 1 136 ? -22.173 -18.226 -2.617  1.000 43.004  0  246 ALA   D N   1 ? 
ATOM   864  C  CA  . ALA   A 1 136 ? -22.183 -17.863 -4.031  1.000 42.363  0  246 ALA   D CA  1 ? 
ATOM   865  C  C   . ALA   A 1 136 ? -20.761 -17.718 -4.579  1.000 39.961  0  246 ALA   D C   1 ? 
ATOM   866  O  O   . ALA   A 1 136 ? -20.486 -18.126 -5.704  1.000 41.312  0  246 ALA   D O   1 ? 
ATOM   867  C  CB  . ALA   A 1 136 ? -22.972 -16.587 -4.223  1.000 38.837  0  246 ALA   D CB  1 ? 
ATOM   868  N  N   . LEU   A 1 137 ? -19.865 -17.143 -3.770  1.000 41.216  0  247 LEU   D N   1 ? 
ATOM   869  C  CA  . LEU   A 1 137 ? -18.522 -16.795 -4.224  1.000 45.192  0  247 LEU   D CA  1 ? 
ATOM   870  C  C   . LEU   A 1 137 ? -17.637 -18.044 -4.361  1.000 41.714  0  247 LEU   D C   1 ? 
ATOM   871  O  O   . LEU   A 1 137 ? -16.556 -17.963 -4.939  1.000 37.171  0  247 LEU   D O   1 ? 
ATOM   872  C  CB  . LEU   A 1 137 ? -17.918 -15.785 -3.247  1.000 46.178  0  247 LEU   D CB  1 ? 
ATOM   873  C  CG  . LEU   A 1 137 ? -18.578 -14.402 -3.223  1.000 49.335  0  247 LEU   D CG  1 ? 
ATOM   874  C  CD1 . LEU   A 1 137 ? -18.152 -13.612 -2.000  1.000 50.513  0  247 LEU   D CD1 1 ? 
ATOM   875  C  CD2 . LEU   A 1 137 ? -18.260 -13.627 -4.494  1.000 47.388  0  247 LEU   D CD2 1 ? 
ATOM   876  N  N   . GLN   A 1 138 ? -18.119 -19.200 -3.858  1.000 42.093  0  248 GLN   D N   1 ? 
ATOM   877  C  CA  . GLN   A 1 138 ? -17.307 -20.413 -3.792  1.000 43.942  0  248 GLN   D CA  1 ? 
ATOM   878  C  C   . GLN   A 1 138 ? -17.801 -21.472 -4.792  1.000 40.958  0  248 GLN   D C   1 ? 
ATOM   879  O  O   . GLN   A 1 138 ? -17.031 -22.337 -5.199  1.000 40.953  0  248 GLN   D O   1 ? 
ATOM   880  C  CB  . GLN   A 1 138 ? -17.328 -20.974 -2.369  1.000 48.685  0  248 GLN   D CB  1 ? 
ATOM   881  C  CG  . GLN   A 1 138 ? -16.977 -19.949 -1.294  1.000 69.164  0  248 GLN   D CG  1 ? 
ATOM   882  C  CD  . GLN   A 1 138 ? -16.976 -20.529 0.105   1.000 89.046  0  248 GLN   D CD  1 ? 
ATOM   883  O  OE1 . GLN   A 1 138 ? -17.817 -20.189 0.946   1.000 90.495  0  248 GLN   D OE1 1 ? 
ATOM   884  N  NE2 . GLN   A 1 138 ? -16.038 -21.431 0.361   1.000 97.788  0  248 GLN   D NE2 1 ? 
ATOM   885  N  N   . LEU   A 1 139 ? -19.094 -21.427 -5.149  1.000 42.298  0  249 LEU   D N   1 ? 
ATOM   886  C  CA  . LEU   A 1 139 ? -19.688 -22.460 -5.997  1.000 46.240  0  249 LEU   D CA  1 ? 
ATOM   887  C  C   . LEU   A 1 139 ? -19.501 -22.113 -7.472  1.000 38.467  0  249 LEU   D C   1 ? 
ATOM   888  O  O   . LEU   A 1 139 ? -19.488 -20.941 -7.844  1.000 37.017  0  249 LEU   D O   1 ? 
ATOM   889  C  CB  . LEU   A 1 139 ? -21.163 -22.670 -5.662  1.000 50.665  0  249 LEU   D CB  1 ? 
ATOM   890  C  CG  . LEU   A 1 139 ? -21.456 -23.753 -4.621  1.000 66.180  0  249 LEU   D CG  1 ? 
ATOM   891  C  CD1 . LEU   A 1 139 ? -20.797 -23.440 -3.290  1.000 68.462  0  249 LEU   D CD1 1 ? 
ATOM   892  C  CD2 . LEU   A 1 139 ? -22.950 -23.945 -4.455  1.000 78.947  0  249 LEU   D CD2 1 ? 
ATOM   893  N  N   . PRO   A 1 140 ? -19.349 -23.132 -8.358  1.000 36.126  0  250 PRO   D N   1 ? 
ATOM   894  C  CA  . PRO   A 1 140 ? -19.296 -22.897 -9.799  1.000 34.674  0  250 PRO   D CA  1 ? 
ATOM   895  C  C   . PRO   A 1 140 ? -20.656 -22.443 -10.321 1.000 35.644  0  250 PRO   D C   1 ? 
ATOM   896  O  O   . PRO   A 1 140 ? -21.690 -22.835 -9.782  1.000 31.362  0  250 PRO   D O   1 ? 
ATOM   897  C  CB  . PRO   A 1 140 ? -18.864 -24.255 -10.405 1.000 35.030  0  250 PRO   D CB  1 ? 
ATOM   898  C  CG  . PRO   A 1 140 ? -18.408 -25.089 -9.202  1.000 36.835  0  250 PRO   D CG  1 ? 
ATOM   899  C  CD  . PRO   A 1 140 ? -19.155 -24.543 -8.009  1.000 34.110  0  250 PRO   D CD  1 ? 
ATOM   900  N  N   . CYS   A 1 141 ? -20.638 -21.650 -11.405 1.000 34.449  0  251 CYS   D N   1 ? 
ATOM   901  C  CA  . CYS   A 1 141 ? -21.856 -21.099 -11.981 1.000 36.834  0  251 CYS   D CA  1 ? 
ATOM   902  C  C   . CYS   A 1 141 ? -22.379 -21.997 -13.112 1.000 36.953  0  251 CYS   D C   1 ? 
ATOM   903  O  O   . CYS   A 1 141 ? -23.403 -21.692 -13.711 1.000 43.826  0  251 CYS   D O   1 ? 
ATOM   904  C  CB  . CYS   A 1 141 ? -21.635 -19.665 -12.456 1.000 39.802  0  251 CYS   D CB  1 ? 
ATOM   905  S  SG  . CYS   A 1 141 ? -20.278 -19.487 -13.642 1.000 46.809  0  251 CYS   D SG  1 ? 
ATOM   906  N  N   . GLU   A 1 142 ? -21.668 -23.109 -13.387 1.000 42.226  0  252 GLU   D N   1 ? 
ATOM   907  C  CA  . GLU   A 1 142 ? -22.049 -24.046 -14.445 1.000 44.069  0  252 GLU   D CA  1 ? 
ATOM   908  C  C   . GLU   A 1 142 ? -21.811 -25.480 -13.960 1.000 42.559  0  252 GLU   D C   1 ? 
ATOM   909  O  O   . GLU   A 1 142 ? -20.887 -25.730 -13.187 1.000 47.279  0  252 GLU   D O   1 ? 
ATOM   910  C  CB  . GLU   A 1 142 ? -21.241 -23.778 -15.722 1.000 44.677  0  252 GLU   D CB  1 ? 
ATOM   911  C  CG  . GLU   A 1 142 ? -21.458 -22.383 -16.310 1.000 46.933  0  252 GLU   D CG  1 ? 
ATOM   912  C  CD  . GLU   A 1 142 ? -22.829 -22.144 -16.930 1.000 52.243  0  252 GLU   D CD  1 ? 
ATOM   913  O  OE1 . GLU   A 1 142 ? -23.520 -23.126 -17.266 1.000 46.675  0  252 GLU   D OE1 1 ? 
ATOM   914  O  OE2 . GLU   A 1 142 ? -23.232 -20.966 -17.008 1.000 50.469  0  252 GLU   D OE2 1 ? 
ATOM   915  N  N   . SER   A 1 143 ? -22.642 -26.417 -14.445 1.000 42.121  0  253 SER   D N   1 ? 
ATOM   916  C  CA  . SER   A 1 143 ? -22.560 -27.818 -14.034 1.000 50.359  0  253 SER   D CA  1 ? 
ATOM   917  C  C   . SER   A 1 143 ? -22.243 -28.721 -15.232 1.000 44.810  0  253 SER   D C   1 ? 
ATOM   918  O  O   . SER   A 1 143 ? -21.590 -29.751 -15.069 1.000 45.053  0  253 SER   D O   1 ? 
ATOM   919  C  CB  . SER   A 1 143 ? -23.828 -28.256 -13.352 1.000 52.712  0  253 SER   D CB  1 ? 
ATOM   920  O  OG  . SER   A 1 143 ? -24.910 -28.296 -14.267 1.000 51.027  0  253 SER   D OG  1 ? 
ATOM   921  N  N   . SER   A 1 144 ? -22.773 -28.359 -16.416 1.000 40.618  0  254 SER   D N   1 ? 
ATOM   922  C  CA  . SER   A 1 144 ? -22.571 -29.132 -17.640 1.000 39.889  0  254 SER   D CA  1 ? 
ATOM   923  C  C   . SER   A 1 144 ? -21.105 -29.555 -17.769 1.000 43.715  0  254 SER   D C   1 ? 
ATOM   924  O  O   . SER   A 1 144 ? -20.215 -28.711 -17.817 1.000 44.794  0  254 SER   D O   1 ? 
ATOM   925  C  CB  . SER   A 1 144 ? -23.015 -28.357 -18.843 1.000 38.563  0  254 SER   D CB  1 ? 
ATOM   926  O  OG  . SER   A 1 144 ? -22.615 -29.006 -20.040 1.000 49.170  0  254 SER   D OG  1 ? 
ATOM   927  N  N   . ALA   A 1 145 ? -20.882 -30.873 -17.877 1.000 43.705  0  255 ALA   D N   1 ? 
ATOM   928  C  CA  . ALA   A 1 145 ? -19.540 -31.438 -17.898 1.000 46.976  0  255 ALA   D CA  1 ? 
ATOM   929  C  C   . ALA   A 1 145 ? -18.779 -30.970 -19.142 1.000 47.564  0  255 ALA   D C   1 ? 
ATOM   930  O  O   . ALA   A 1 145 ? -17.596 -30.650 -19.059 1.000 45.935  0  255 ALA   D O   1 ? 
ATOM   931  C  CB  . ALA   A 1 145 ? -19.621 -32.947 -17.834 1.000 48.320  0  255 ALA   D CB  1 ? 
ATOM   932  N  N   . VAL   A 1 146 ? -19.475 -30.934 -20.290 1.000 42.202  0  256 VAL   D N   1 ? 
ATOM   933  C  CA  . VAL   A 1 146 ? -18.869 -30.536 -21.557 1.000 44.414  0  256 VAL   D CA  1 ? 
ATOM   934  C  C   . VAL   A 1 146 ? -18.415 -29.076 -21.465 1.000 41.197  0  256 VAL   D C   1 ? 
ATOM   935  O  O   . VAL   A 1 146 ? -17.316 -28.741 -21.900 1.000 43.958  0  256 VAL   D O   1 ? 
ATOM   936  C  CB  . VAL   A 1 146 ? -19.839 -30.753 -22.743 1.000 47.522  0  256 VAL   D CB  1 ? 
ATOM   937  C  CG1 . VAL   A 1 146 ? -19.372 -30.045 -24.012 1.000 46.617  0  256 VAL   D CG1 1 ? 
ATOM   938  C  CG2 . VAL   A 1 146 ? -20.070 -32.231 -23.016 1.000 51.595  0  256 VAL   D CG2 1 ? 
ATOM   939  N  N   . VAL   A 1 147 ? -19.287 -28.216 -20.917 1.000 39.281  0  257 VAL   D N   1 ? 
ATOM   940  C  CA  . VAL   A 1 147 ? -19.002 -26.791 -20.785 1.000 37.166  0  257 VAL   D CA  1 ? 
ATOM   941  C  C   . VAL   A 1 147 ? -17.828 -26.596 -19.821 1.000 36.043  0  257 VAL   D C   1 ? 
ATOM   942  O  O   . VAL   A 1 147 ? -16.886 -25.875 -20.131 1.000 37.617  0  257 VAL   D O   1 ? 
ATOM   943  C  CB  . VAL   A 1 147 ? -20.250 -26.016 -20.311 1.000 39.627  0  257 VAL   D CB  1 ? 
ATOM   944  C  CG1 . VAL   A 1 147 ? -19.926 -24.569 -19.947 1.000 40.276  0  257 VAL   D CG1 1 ? 
ATOM   945  C  CG2 . VAL   A 1 147 ? -21.375 -26.070 -21.344 1.000 40.892  0  257 VAL   D CG2 1 ? 
ATOM   946  N  N   . VAL   A 1 148 ? -17.900 -27.255 -18.657 1.000 36.447  0  258 VAL   D N   1 ? 
ATOM   947  C  CA  . VAL   A 1 148 ? -16.901 -27.099 -17.607 1.000 42.299  0  258 VAL   D CA  1 ? 
ATOM   948  C  C   . VAL   A 1 148 ? -15.551 -27.634 -18.093 1.000 43.696  0  258 VAL   D C   1 ? 
ATOM   949  O  O   . VAL   A 1 148 ? -14.512 -27.030 -17.826 1.000 42.295  0  258 VAL   D O   1 ? 
ATOM   950  C  CB  . VAL   A 1 148 ? -17.347 -27.796 -16.303 1.000 45.058  0  258 VAL   D CB  1 ? 
ATOM   951  C  CG1 . VAL   A 1 148 ? -16.185 -28.015 -15.340 1.000 44.059  0  258 VAL   D CG1 1 ? 
ATOM   952  C  CG2 . VAL   A 1 148 ? -18.476 -27.036 -15.614 1.000 46.179  0  258 VAL   D CG2 1 ? 
ATOM   953  N  N   . SER   A 1 149 ? -15.576 -28.782 -18.779 1.000 42.871  0  259 SER   D N   1 ? 
ATOM   954  C  CA  . SER   A 1 149 ? -14.354 -29.414 -19.259 1.000 46.786  0  259 SER   D CA  1 ? 
ATOM   955  C  C   . SER   A 1 149 ? -13.631 -28.491 -20.247 1.000 43.838  0  259 SER   D C   1 ? 
ATOM   956  O  O   . SER   A 1 149 ? -12.406 -28.381 -20.216 1.000 42.064  0  259 SER   D O   1 ? 
ATOM   957  C  CB  . SER   A 1 149 ? -14.643 -30.755 -19.874 1.000 49.051  0  259 SER   D CB  1 ? 
ATOM   958  O  OG  . SER   A 1 149 ? -13.442 -31.405 -20.264 1.000 72.562  0  259 SER   D OG  1 ? 
ATOM   959  N  N   . GLY   A 1 150 ? -14.409 -27.816 -21.104 1.000 39.559  0  260 GLY   D N   1 ? 
ATOM   960  C  CA  . GLY   A 1 150 ? -13.861 -26.932 -22.121 1.000 37.141  0  260 GLY   D CA  1 ? 
ATOM   961  C  C   . GLY   A 1 150 ? -13.363 -25.617 -21.522 1.000 39.886  0  260 GLY   D C   1 ? 
ATOM   962  O  O   . GLY   A 1 150 ? -12.341 -25.090 -21.949 1.000 42.318  0  260 GLY   D O   1 ? 
ATOM   963  N  N   . LEU   A 1 151 ? -14.109 -25.087 -20.544 1.000 38.328  0  261 LEU   D N   1 ? 
ATOM   964  C  CA  . LEU   A 1 151 ? -13.765 -23.820 -19.914 1.000 40.869  0  261 LEU   D CA  1 ? 
ATOM   965  C  C   . LEU   A 1 151 ? -12.498 -23.978 -19.064 1.000 40.337  0  261 LEU   D C   1 ? 
ATOM   966  O  O   . LEU   A 1 151 ? -11.730 -23.028 -18.917 1.000 33.397  0  261 LEU   D O   1 ? 
ATOM   967  C  CB  . LEU   A 1 151 ? -14.942 -23.302 -19.085 1.000 42.222  0  261 LEU   D CB  1 ? 
ATOM   968  C  CG  . LEU   A 1 151 ? -16.141 -22.765 -19.878 1.000 44.148  0  261 LEU   D CG  1 ? 
ATOM   969  C  CD1 . LEU   A 1 151 ? -17.258 -22.346 -18.943 1.000 45.019  0  261 LEU   D CD1 1 ? 
ATOM   970  C  CD2 . LEU   A 1 151 ? -15.745 -21.606 -20.779 1.000 46.962  0  261 LEU   D CD2 1 ? 
ATOM   971  N  N   . ARG   A 1 152 ? -12.270 -25.191 -18.540 1.000 38.442  0  262 ARG   D N   1 ? 
ATOM   972  C  CA  . ARG   A 1 152 ? -11.102 -25.456 -17.711 1.000 42.168  0  262 ARG   D CA  1 ? 
ATOM   973  C  C   . ARG   A 1 152 ? -9.820  -25.357 -18.549 1.000 40.865  0  262 ARG   D C   1 ? 
ATOM   974  O  O   . ARG   A 1 152 ? -8.762  -25.050 -18.009 1.000 45.420  0  262 ARG   D O   1 ? 
ATOM   975  C  CB  . ARG   A 1 152 ? -11.210 -26.803 -16.976 1.000 45.485  0  262 ARG   D CB  1 ? 
ATOM   976  C  CG  . ARG   A 1 152 ? -11.978 -26.715 -15.660 1.000 57.158  0  262 ARG   D CG  1 ? 
ATOM   977  C  CD  . ARG   A 1 152 ? -11.736 -27.909 -14.726 1.000 58.310  0  262 ARG   D CD  1 ? 
ATOM   978  N  NE  . ARG   A 1 152 ? -12.746 -28.970 -14.840 1.000 62.482  0  262 ARG   D NE  1 ? 
ATOM   979  C  CZ  . ARG   A 1 152 ? -13.544 -29.375 -13.840 1.000 58.632  0  262 ARG   D CZ  1 ? 
ATOM   980  N  NH1 . ARG   A 1 152 ? -13.522 -28.752 -12.672 1.000 60.390  0  262 ARG   D NH1 1 ? 
ATOM   981  N  NH2 . ARG   A 1 152 ? -14.396 -30.366 -14.032 1.000 72.613  0  262 ARG   D NH2 1 ? 
ATOM   982  N  N   . THR   A 1 153 ? -9.934  -25.566 -19.875 1.000 33.502  0  263 THR   D N   1 ? 
ATOM   983  C  CA  . THR   A 1 153 ? -8.771  -25.510 -20.760 1.000 36.286  0  263 THR   D CA  1 ? 
ATOM   984  C  C   . THR   A 1 153 ? -8.380  -24.047 -21.021 1.000 40.740  0  263 THR   D C   1 ? 
ATOM   985  O  O   . THR   A 1 153 ? -7.296  -23.784 -21.538 1.000 38.557  0  263 THR   D O   1 ? 
ATOM   986  C  CB  . THR   A 1 153 ? -9.053  -26.245 -22.077 1.000 38.383  0  263 THR   D CB  1 ? 
ATOM   987  O  OG1 . THR   A 1 153 ? -10.015 -25.468 -22.784 1.000 39.842  0  263 THR   D OG1 1 ? 
ATOM   988  C  CG2 . THR   A 1 153 ? -9.546  -27.667 -21.871 1.000 37.500  0  263 THR   D CG2 1 ? 
ATOM   989  N  N   . LEU   A 1 154 ? -9.292  -23.107 -20.710 1.000 37.272  0  264 LEU   D N   1 ? 
ATOM   990  C  CA  . LEU   A 1 154 ? -9.073  -21.694 -20.995 1.000 35.454  0  264 LEU   D CA  1 ? 
ATOM   991  C  C   . LEU   A 1 154 ? -8.540  -20.967 -19.757 1.000 35.662  0  264 LEU   D C   1 ? 
ATOM   992  O  O   . LEU   A 1 154 ? -7.940  -19.902 -19.883 1.000 37.344  0  264 LEU   D O   1 ? 
ATOM   993  C  CB  . LEU   A 1 154 ? -10.375 -21.064 -21.484 1.000 34.982  0  264 LEU   D CB  1 ? 
ATOM   994  C  CG  . LEU   A 1 154 ? -10.945 -21.616 -22.794 1.000 34.297  0  264 LEU   D CG  1 ? 
ATOM   995  C  CD1 . LEU   A 1 154 ? -12.245 -20.917 -23.129 1.000 33.036  0  264 LEU   D CD1 1 ? 
ATOM   996  C  CD2 . LEU   A 1 154 ? -9.958  -21.479 -23.940 1.000 34.165  0  264 LEU   D CD2 1 ? 
ATOM   997  N  N   . VAL   A 1 155 ? -8.791  -21.534 -18.566 1.000 35.367  0  265 VAL   D N   1 ? 
ATOM   998  C  CA  . VAL   A 1 155 ? -8.447  -20.884 -17.307 1.000 39.643  0  265 VAL   D CA  1 ? 
ATOM   999  C  C   . VAL   A 1 155 ? -6.936  -20.622 -17.265 1.000 47.531  0  265 VAL   D C   1 ? 
ATOM   1000 O  O   . VAL   A 1 155 ? -6.138  -21.546 -17.424 1.000 41.287  0  265 VAL   D O   1 ? 
ATOM   1001 C  CB  . VAL   A 1 155 ? -8.899  -21.725 -16.098 1.000 38.603  0  265 VAL   D CB  1 ? 
ATOM   1002 C  CG1 . VAL   A 1 155 ? -8.295  -21.218 -14.790 1.000 37.028  0  265 VAL   D CG1 1 ? 
ATOM   1003 C  CG2 . VAL   A 1 155 ? -10.419 -21.798 -15.995 1.000 39.351  0  265 VAL   D CG2 1 ? 
ATOM   1004 N  N   . PRO   A 1 156 ? -6.502  -19.353 -17.048 1.000 53.475  0  266 PRO   D N   1 ? 
ATOM   1005 C  CA  . PRO   A 1 156 ? -5.081  -19.039 -16.903 1.000 59.531  0  266 PRO   D CA  1 ? 
ATOM   1006 C  C   . PRO   A 1 156 ? -4.580  -19.292 -15.483 1.000 52.150  0  266 PRO   D C   1 ? 
ATOM   1007 O  O   . PRO   A 1 156 ? -3.710  -20.169 -15.339 1.000 61.188  0  266 PRO   D O   1 ? 
ATOM   1008 C  CB  . PRO   A 1 156 ? -5.038  -17.548 -17.289 1.000 55.836  0  266 PRO   D CB  1 ? 
ATOM   1009 C  CG  . PRO   A 1 156 ? -6.369  -17.007 -16.787 1.000 54.204  0  266 PRO   D CG  1 ? 
ATOM   1010 C  CD  . PRO   A 1 156 ? -7.357  -18.155 -16.985 1.000 53.916  0  266 PRO   D CD  1 ? 
ATOM   1011 N  N   . PRO   B 1 30  ? -9.818  -27.054 -11.335 1.000 53.794  0  140 PRO   A N   1 ? 
ATOM   1012 C  CA  . PRO   B 1 30  ? -10.094 -25.623 -11.246 1.000 54.481  0  140 PRO   A CA  1 ? 
ATOM   1013 C  C   . PRO   B 1 30  ? -11.598 -25.365 -11.306 1.000 52.225  0  140 PRO   A C   1 ? 
ATOM   1014 O  O   . PRO   B 1 30  ? -12.304 -25.943 -12.133 1.000 53.801  0  140 PRO   A O   1 ? 
ATOM   1015 C  CB  . PRO   B 1 30  ? -9.329  -24.978 -12.417 1.000 49.887  0  140 PRO   A CB  1 ? 
ATOM   1016 C  CG  . PRO   B 1 30  ? -9.066  -26.126 -13.367 1.000 50.341  0  140 PRO   A CG  1 ? 
ATOM   1017 C  CD  . PRO   B 1 30  ? -9.044  -27.378 -12.508 1.000 48.362  0  140 PRO   A CD  1 ? 
ATOM   1018 N  N   . LYS   B 1 31  ? -12.063 -24.451 -10.450 1.000 46.452  0  141 LYS   A N   1 ? 
ATOM   1019 C  CA  . LYS   B 1 31  ? -13.482 -24.291 -10.176 1.000 46.719  0  141 LYS   A CA  1 ? 
ATOM   1020 C  C   . LYS   B 1 31  ? -14.025 -23.125 -11.005 1.000 41.716  0  141 LYS   A C   1 ? 
ATOM   1021 O  O   . LYS   B 1 31  ? -13.555 -21.995 -10.876 1.000 39.773  0  141 LYS   A O   1 ? 
ATOM   1022 C  CB  . LYS   B 1 31  ? -13.635 -24.073 -8.665  1.000 51.672  0  141 LYS   A CB  1 ? 
ATOM   1023 C  CG  . LYS   B 1 31  ? -14.807 -24.774 -8.014  1.000 57.220  0  141 LYS   A CG  1 ? 
ATOM   1024 C  CD  . LYS   B 1 31  ? -14.801 -24.664 -6.495  1.000 58.283  0  141 LYS   A CD  1 ? 
ATOM   1025 C  CE  . LYS   B 1 31  ? -15.758 -25.606 -5.842  1.000 70.300  0  141 LYS   A CE  1 ? 
ATOM   1026 N  NZ  . LYS   B 1 31  ? -15.735 -25.468 -4.382  1.000 74.294  0  141 LYS   A NZ  1 ? 
ATOM   1027 N  N   . ILE   B 1 32  ? -15.029 -23.413 -11.850 1.000 39.037  0  142 ILE   A N   1 ? 
ATOM   1028 C  CA  . ILE   B 1 32  ? -15.578 -22.421 -12.766 1.000 40.225  0  142 ILE   A CA  1 ? 
ATOM   1029 C  C   . ILE   B 1 32  ? -16.591 -21.564 -12.012 1.000 39.560  0  142 ILE   A C   1 ? 
ATOM   1030 O  O   . ILE   B 1 32  ? -17.798 -21.706 -12.200 1.000 40.269  0  142 ILE   A O   1 ? 
ATOM   1031 C  CB  . ILE   B 1 32  ? -16.199 -23.093 -14.016 1.000 37.184  0  142 ILE   A CB  1 ? 
ATOM   1032 C  CG1 . ILE   B 1 32  ? -15.212 -24.050 -14.697 1.000 37.198  0  142 ILE   A CG1 1 ? 
ATOM   1033 C  CG2 . ILE   B 1 32  ? -16.731 -22.047 -15.003 1.000 38.155  0  142 ILE   A CG2 1 ? 
ATOM   1034 C  CD1 . ILE   B 1 32  ? -13.924 -23.388 -15.171 1.000 34.672  0  142 ILE   A CD1 1 ? 
ATOM   1035 N  N   . THR   B 1 33  ? -16.076 -20.681 -11.149 1.000 43.462  0  143 THR   A N   1 ? 
ATOM   1036 C  CA  . THR   B 1 33  ? -16.901 -19.718 -10.436 1.000 39.608  0  143 THR   A CA  1 ? 
ATOM   1037 C  C   . THR   B 1 33  ? -17.158 -18.525 -11.353 1.000 38.114  0  143 THR   A C   1 ? 
ATOM   1038 O  O   . THR   B 1 33  ? -16.596 -18.442 -12.445 1.000 34.343  0  143 THR   A O   1 ? 
ATOM   1039 C  CB  . THR   B 1 33  ? -16.201 -19.297 -9.139  1.000 41.547  0  143 THR   A CB  1 ? 
ATOM   1040 O  OG1 . THR   B 1 33  ? -14.969 -18.693 -9.522  1.000 35.636  0  143 THR   A OG1 1 ? 
ATOM   1041 C  CG2 . THR   B 1 33  ? -15.933 -20.470 -8.212  1.000 41.775  0  143 THR   A CG2 1 ? 
ATOM   1042 N  N   . LEU   B 1 34  ? -17.997 -17.598 -10.887 1.000 39.619  0  144 LEU   A N   1 ? 
ATOM   1043 C  CA  . LEU   B 1 34  ? -18.272 -16.373 -11.621 1.000 41.860  0  144 LEU   A CA  1 ? 
ATOM   1044 C  C   . LEU   B 1 34  ? -16.966 -15.604 -11.821 1.000 38.093  0  144 LEU   A C   1 ? 
ATOM   1045 O  O   . LEU   B 1 34  ? -16.664 -15.167 -12.929 1.000 34.991  0  144 LEU   A O   1 ? 
ATOM   1046 C  CB  . LEU   B 1 34  ? -19.307 -15.540 -10.866 1.000 49.767  0  144 LEU   A CB  1 ? 
ATOM   1047 C  CG  . LEU   B 1 34  ? -20.708 -16.149 -10.753 1.000 62.468  0  144 LEU   A CG  1 ? 
ATOM   1048 C  CD1 . LEU   B 1 34  ? -21.514 -15.478 -9.644  1.000 63.554  0  144 LEU   A CD1 1 ? 
ATOM   1049 C  CD2 . LEU   B 1 34  ? -21.440 -16.047 -12.084 1.000 65.604  0  144 LEU   A CD2 1 ? 
ATOM   1050 N  N   . LEU   B 1 35  ? -16.163 -15.515 -10.750 1.000 36.039  0  145 LEU   A N   1 ? 
ATOM   1051 C  CA  . LEU   B 1 35  ? -14.926 -14.748 -10.766 1.000 33.361  0  145 LEU   A CA  1 ? 
ATOM   1052 C  C   . LEU   B 1 35  ? -13.930 -15.380 -11.743 1.000 34.186  0  145 LEU   A C   1 ? 
ATOM   1053 O  O   . LEU   B 1 35  ? -13.274 -14.670 -12.503 1.000 35.768  0  145 LEU   A O   1 ? 
ATOM   1054 C  CB  . LEU   B 1 35  ? -14.354 -14.663 -9.351  1.000 34.607  0  145 LEU   A CB  1 ? 
ATOM   1055 C  CG  . LEU   B 1 35  ? -13.050 -13.872 -9.195  1.000 37.770  0  145 LEU   A CG  1 ? 
ATOM   1056 C  CD1 . LEU   B 1 35  ? -13.200 -12.439 -9.696  1.000 37.138  0  145 LEU   A CD1 1 ? 
ATOM   1057 C  CD2 . LEU   B 1 35  ? -12.592 -13.885 -7.747  1.000 34.896  0  145 LEU   A CD2 1 ? 
ATOM   1058 N  N   . THR   B 1 36  ? -13.818 -16.719 -11.704 1.000 36.737  0  146 THR   A N   1 ? 
ATOM   1059 C  CA  . THR   B 1 36  ? -12.928 -17.450 -12.604 1.000 38.455  0  146 THR   A CA  1 ? 
ATOM   1060 C  C   . THR   B 1 36  ? -13.337 -17.182 -14.054 1.000 39.294  0  146 THR   A C   1 ? 
ATOM   1061 O  O   . THR   B 1 36  ? -12.483 -17.045 -14.929 1.000 39.764  0  146 THR   A O   1 ? 
ATOM   1062 C  CB  . THR   B 1 36  ? -12.974 -18.943 -12.275 1.000 41.946  0  146 THR   A CB  1 ? 
ATOM   1063 O  OG1 . THR   B 1 36  ? -12.368 -19.059 -10.993 1.000 44.213  0  146 THR   A OG1 1 ? 
ATOM   1064 C  CG2 . THR   B 1 36  ? -12.210 -19.793 -13.275 1.000 43.611  0  146 THR   A CG2 1 ? 
ATOM   1065 N  N   . LEU   B 1 37  ? -14.650 -17.109 -14.289 1.000 38.042  0  147 LEU   A N   1 ? 
ATOM   1066 C  CA  . LEU   B 1 37  ? -15.185 -16.889 -15.621 1.000 36.141  0  147 LEU   A CA  1 ? 
ATOM   1067 C  C   . LEU   B 1 37  ? -14.767 -15.501 -16.123 1.000 32.114  0  147 LEU   A C   1 ? 
ATOM   1068 O  O   . LEU   B 1 37  ? -14.398 -15.349 -17.284 1.000 33.598  0  147 LEU   A O   1 ? 
ATOM   1069 C  CB  . LEU   B 1 37  ? -16.705 -17.045 -15.578 1.000 38.668  0  147 LEU   A CB  1 ? 
ATOM   1070 C  CG  . LEU   B 1 37  ? -17.380 -17.420 -16.895 1.000 40.911  0  147 LEU   A CG  1 ? 
ATOM   1071 C  CD1 . LEU   B 1 37  ? -17.083 -18.867 -17.257 1.000 42.034  0  147 LEU   A CD1 1 ? 
ATOM   1072 C  CD2 . LEU   B 1 37  ? -18.877 -17.177 -16.817 1.000 45.850  0  147 LEU   A CD2 1 ? 
ATOM   1073 N  N   . ILE   B 1 38  ? -14.818 -14.497 -15.228 1.000 36.592  0  148 ILE   A N   1 ? 
ATOM   1074 C  CA  . ILE   B 1 38  ? -14.442 -13.125 -15.572 1.000 35.643  0  148 ILE   A CA  1 ? 
ATOM   1075 C  C   . ILE   B 1 38  ? -12.939 -13.072 -15.860 1.000 35.814  0  148 ILE   A C   1 ? 
ATOM   1076 O  O   . ILE   B 1 38  ? -12.516 -12.447 -16.832 1.000 34.250  0  148 ILE   A O   1 ? 
ATOM   1077 C  CB  . ILE   B 1 38  ? -14.839 -12.131 -14.453 1.000 37.195  0  148 ILE   A CB  1 ? 
ATOM   1078 C  CG1 . ILE   B 1 38  ? -16.345 -12.172 -14.147 1.000 39.135  0  148 ILE   A CG1 1 ? 
ATOM   1079 C  CG2 . ILE   B 1 38  ? -14.380 -10.711 -14.788 1.000 42.244  0  148 ILE   A CG2 1 ? 
ATOM   1080 C  CD1 . ILE   B 1 38  ? -17.239 -11.929 -15.351 1.000 45.157  0  148 ILE   A CD1 1 ? 
ATOM   1081 N  N   . LYS   B 1 39  ? -12.144 -13.739 -15.005 1.000 36.749  0  149 LYS   A N   1 ? 
ATOM   1082 C  CA  . LYS   B 1 39  ? -10.689 -13.728 -15.126 1.000 38.572  0  149 LYS   A CA  1 ? 
ATOM   1083 C  C   . LYS   B 1 39  ? -10.261 -14.392 -16.433 1.000 32.374  0  149 LYS   A C   1 ? 
ATOM   1084 O  O   . LYS   B 1 39  ? -9.285  -13.970 -17.049 1.000 38.156  0  149 LYS   A O   1 ? 
ATOM   1085 C  CB  . LYS   B 1 39  ? -10.024 -14.402 -13.915 1.000 44.745  0  149 LYS   A CB  1 ? 
ATOM   1086 C  CG  . LYS   B 1 39  ? -10.161 -13.634 -12.599 1.000 54.890  0  149 LYS   A CG  1 ? 
ATOM   1087 C  CD  . LYS   B 1 39  ? -9.574  -12.223 -12.641 1.000 71.127  0  149 LYS   A CD  1 ? 
ATOM   1088 C  CE  . LYS   B 1 39  ? -10.074 -11.340 -11.539 1.000 83.933  0  149 LYS   A CE  1 ? 
ATOM   1089 N  NZ  . LYS   B 1 39  ? -9.704  -9.937  -11.766 1.000 79.303  0  149 LYS   A NZ  1 ? 
ATOM   1090 N  N   . THR   B 1 40  ? -10.999 -15.427 -16.850 1.000 31.670  0  150 THR   A N   1 ? 
ATOM   1091 C  CA  . THR   B 1 40  ? -10.700 -16.132 -18.088 1.000 32.851  0  150 THR   A CA  1 ? 
ATOM   1092 C  C   . THR   B 1 40  ? -11.002 -15.219 -19.280 1.000 32.574  0  150 THR   A C   1 ? 
ATOM   1093 O  O   . THR   B 1 40  ? -10.265 -15.222 -20.265 1.000 33.699  0  150 THR   A O   1 ? 
ATOM   1094 C  CB  . THR   B 1 40  ? -11.499 -17.433 -18.145 1.000 32.626  0  150 THR   A CB  1 ? 
ATOM   1095 O  OG1 . THR   B 1 40  ? -11.049 -18.186 -17.025 1.000 30.456  0  150 THR   A OG1 1 ? 
ATOM   1096 C  CG2 . THR   B 1 40  ? -11.254 -18.219 -19.421 1.000 36.141  0  150 THR   A CG2 1 ? 
ATOM   1097 N  N   . ALA   B 1 41  ? -12.095 -14.444 -19.176 1.000 36.241  0  151 ALA   A N   1 ? 
ATOM   1098 C  CA  . ALA   B 1 41  ? -12.499 -13.526 -20.237 1.000 36.408  0  151 ALA   A CA  1 ? 
ATOM   1099 C  C   . ALA   B 1 41  ? -11.489 -12.382 -20.357 1.000 35.860  0  151 ALA   A C   1 ? 
ATOM   1100 O  O   . ALA   B 1 41  ? -11.119 -11.997 -21.467 1.000 33.059  0  151 ALA   A O   1 ? 
ATOM   1101 C  CB  . ALA   B 1 41  ? -13.892 -13.005 -19.970 1.000 33.688  0  151 ALA   A CB  1 ? 
ATOM   1102 N  N   . GLU   B 1 42  ? -11.077 -11.828 -19.200 1.000 34.716  0  152 GLU   A N   1 ? 
ATOM   1103 C  CA  . GLU   B 1 42  ? -10.078 -10.762 -19.157 1.000 38.351  0  152 GLU   A CA  1 ? 
ATOM   1104 C  C   . GLU   B 1 42  ? -8.826  -11.201 -19.912 1.000 37.022  0  152 GLU   A C   1 ? 
ATOM   1105 O  O   . GLU   B 1 42  ? -8.328  -10.473 -20.765 1.000 41.432  0  152 GLU   A O   1 ? 
ATOM   1106 C  CB  . GLU   B 1 42  ? -9.712  -10.384 -17.716 1.000 41.262  0  152 GLU   A CB  1 ? 
ATOM   1107 C  CG  . GLU   B 1 42  ? -10.731 -9.465  -17.046 1.000 50.178  0  152 GLU   A CG  1 ? 
ATOM   1108 C  CD  . GLU   B 1 42  ? -10.429 -9.122  -15.591 1.000 55.145  0  152 GLU   A CD  1 ? 
ATOM   1109 O  OE1 . GLU   B 1 42  ? -9.423  -9.634  -15.045 1.000 57.057  0  152 GLU   A OE1 1 ? 
ATOM   1110 O  OE2 . GLU   B 1 42  ? -11.207 -8.336  -15.002 1.000 47.196  0  152 GLU   A OE2 1 ? 
ATOM   1111 N  N   . HIS   B 1 43  ? -8.339  -12.406 -19.592 1.000 35.043  0  153 HIS   A N   1 ? 
ATOM   1112 C  CA  . HIS   B 1 43  ? -7.110  -12.926 -20.170 1.000 37.728  0  153 HIS   A CA  1 ? 
ATOM   1113 C  C   . HIS   B 1 43  ? -7.246  -13.045 -21.692 1.000 40.784  0  153 HIS   A C   1 ? 
ATOM   1114 O  O   . HIS   B 1 43  ? -6.444  -12.482 -22.434 1.000 40.219  0  153 HIS   A O   1 ? 
ATOM   1115 C  CB  . HIS   B 1 43  ? -6.743  -14.269 -19.526 1.000 35.781  0  153 HIS   A CB  1 ? 
ATOM   1116 C  CG  . HIS   B 1 43  ? -5.488  -14.876 -20.060 1.000 42.496  0  153 HIS   A CG  1 ? 
ATOM   1117 N  ND1 . HIS   B 1 43  ? -4.241  -14.593 -19.544 1.000 49.657  0  153 HIS   A ND1 1 ? 
ATOM   1118 C  CD2 . HIS   B 1 43  ? -5.285  -15.747 -21.063 1.000 45.086  0  153 HIS   A CD2 1 ? 
ATOM   1119 C  CE1 . HIS   B 1 43  ? -3.325  -15.274 -20.218 1.000 49.186  0  153 HIS   A CE1 1 ? 
ATOM   1120 N  NE2 . HIS   B 1 43  ? -3.937  -15.982 -21.144 1.000 50.966  0  153 HIS   A NE2 1 ? 
ATOM   1121 N  N   . TRP   B 1 44  ? -8.292  -13.748 -22.145 1.000 37.307  0  154 TRP   A N   1 ? 
ATOM   1122 C  CA  . TRP   B 1 44  ? -8.417  -14.115 -23.551 1.000 42.619  0  154 TRP   A CA  1 ? 
ATOM   1123 C  C   . TRP   B 1 44  ? -8.868  -12.927 -24.403 1.000 37.546  0  154 TRP   A C   1 ? 
ATOM   1124 O  O   . TRP   B 1 44  ? -8.681  -12.939 -25.614 1.000 40.384  0  154 TRP   A O   1 ? 
ATOM   1125 C  CB  . TRP   B 1 44  ? -9.352  -15.318 -23.714 1.000 38.822  0  154 TRP   A CB  1 ? 
ATOM   1126 C  CG  . TRP   B 1 44  ? -8.677  -16.630 -23.412 1.000 36.228  0  154 TRP   A CG  1 ? 
ATOM   1127 C  CD1 . TRP   B 1 44  ? -8.750  -17.355 -22.261 1.000 38.265  0  154 TRP   A CD1 1 ? 
ATOM   1128 C  CD2 . TRP   B 1 44  ? -7.726  -17.311 -24.254 1.000 37.212  0  154 TRP   A CD2 1 ? 
ATOM   1129 N  NE1 . TRP   B 1 44  ? -7.960  -18.472 -22.351 1.000 37.083  0  154 TRP   A NE1 1 ? 
ATOM   1130 C  CE2 . TRP   B 1 44  ? -7.310  -18.466 -23.555 1.000 35.257  0  154 TRP   A CE2 1 ? 
ATOM   1131 C  CE3 . TRP   B 1 44  ? -7.201  -17.069 -25.531 1.000 35.884  0  154 TRP   A CE3 1 ? 
ATOM   1132 C  CZ2 . TRP   B 1 44  ? -6.393  -19.369 -24.090 1.000 36.101  0  154 TRP   A CZ2 1 ? 
ATOM   1133 C  CZ3 . TRP   B 1 44  ? -6.287  -17.959 -26.056 1.000 37.215  0  154 TRP   A CZ3 1 ? 
ATOM   1134 C  CH2 . TRP   B 1 44  ? -5.891  -19.095 -25.343 1.000 36.537  0  154 TRP   A CH2 1 ? 
ATOM   1135 N  N   . ALA   B 1 45  ? -9.401  -11.884 -23.758 1.000 39.464  0  155 ALA   A N   1 ? 
ATOM   1136 C  CA  . ALA   B 1 45  ? -9.767  -10.659 -24.458 1.000 39.010  0  155 ALA   A CA  1 ? 
ATOM   1137 C  C   . ALA   B 1 45  ? -8.521  -9.987  -25.048 1.000 45.044  0  155 ALA   A C   1 ? 
ATOM   1138 O  O   . ALA   B 1 45  ? -8.600  -9.351  -26.097 1.000 47.228  0  155 ALA   A O   1 ? 
ATOM   1139 C  CB  . ALA   B 1 45  ? -10.501 -9.724  -23.521 1.000 35.513  0  155 ALA   A CB  1 ? 
ATOM   1140 N  N   . ARG   B 1 46  ? -7.367  -10.163 -24.375 1.000 54.375  0  156 ARG   A N   1 ? 
ATOM   1141 C  CA  . ARG   B 1 46  ? -6.141  -9.456  -24.733 1.000 54.463  0  156 ARG   A CA  1 ? 
ATOM   1142 C  C   . ARG   B 1 46  ? -5.265  -10.311 -25.651 1.000 55.177  0  156 ARG   A C   1 ? 
ATOM   1143 O  O   . ARG   B 1 46  ? -4.302  -9.806  -26.224 1.000 65.798  0  156 ARG   A O   1 ? 
ATOM   1144 C  CB  . ARG   B 1 46  ? -5.365  -9.067  -23.468 1.000 49.496  0  156 ARG   A CB  1 ? 
ATOM   1145 C  CG  . ARG   B 1 46  ? -6.216  -8.304  -22.467 1.000 58.827  0  156 ARG   A CG  1 ? 
ATOM   1146 C  CD  . ARG   B 1 46  ? -5.395  -7.546  -21.438 1.000 72.362  0  156 ARG   A CD  1 ? 
ATOM   1147 N  NE  . ARG   B 1 46  ? -6.243  -6.762  -20.527 1.000 94.482  0  156 ARG   A NE  1 ? 
ATOM   1148 C  CZ  . ARG   B 1 46  ? -7.035  -5.738  -20.887 1.000 102.363 0  156 ARG   A CZ  1 ? 
ATOM   1149 N  NH1 . ARG   B 1 46  ? -7.062  -5.318  -22.142 1.000 112.488 0  156 ARG   A NH1 1 ? 
ATOM   1150 N  NH2 . ARG   B 1 46  ? -7.778  -5.125  -19.980 1.000 97.241  0  156 ARG   A NH2 1 ? 
ATOM   1151 N  N   . GLN   B 1 47  ? -5.600  -11.604 -25.781 1.000 58.784  0  157 GLN   A N   1 ? 
ATOM   1152 C  CA  . GLN   B 1 47  ? -4.782  -12.535 -26.549 1.000 58.335  0  157 GLN   A CA  1 ? 
ATOM   1153 C  C   . GLN   B 1 47  ? -5.105  -12.411 -28.037 1.000 57.825  0  157 GLN   A C   1 ? 
ATOM   1154 O  O   . GLN   B 1 47  ? -6.264  -12.260 -28.417 1.000 65.424  0  157 GLN   A O   1 ? 
ATOM   1155 C  CB  . GLN   B 1 47  ? -5.011  -13.979 -26.098 1.000 52.233  0  157 GLN   A CB  1 ? 
ATOM   1156 C  CG  . GLN   B 1 47  ? -4.750  -14.218 -24.616 1.000 57.708  0  157 GLN   A CG  1 ? 
ATOM   1157 C  CD  . GLN   B 1 47  ? -3.368  -13.791 -24.175 1.000 57.747  0  157 GLN   A CD  1 ? 
ATOM   1158 O  OE1 . GLN   B 1 47  ? -3.209  -12.934 -23.297 1.000 59.259  0  157 GLN   A OE1 1 ? 
ATOM   1159 N  NE2 . GLN   B 1 47  ? -2.350  -14.383 -24.785 1.000 51.776  0  157 GLN   A NE2 1 ? 
ATOM   1160 N  N   . ASP   B 1 48  ? -4.056  -12.472 -28.869 1.000 68.694  0  158 ASP   A N   1 ? 
ATOM   1161 C  CA  . ASP   B 1 48  ? -4.214  -12.595 -30.308 1.000 69.725  0  158 ASP   A CA  1 ? 
ATOM   1162 C  C   . ASP   B 1 48  ? -4.544  -14.051 -30.617 1.000 64.828  0  158 ASP   A C   1 ? 
ATOM   1163 O  O   . ASP   B 1 48  ? -3.659  -14.907 -30.602 1.000 71.379  0  158 ASP   A O   1 ? 
ATOM   1164 C  CB  . ASP   B 1 48  ? -2.975  -12.096 -31.042 1.000 73.105  0  158 ASP   A CB  1 ? 
ATOM   1165 C  CG  . ASP   B 1 48  ? -3.013  -12.222 -32.559 1.000 74.334  0  158 ASP   A CG  1 ? 
ATOM   1166 O  OD1 . ASP   B 1 48  ? -2.929  -13.363 -33.055 1.000 72.033  0  158 ASP   A OD1 1 ? 
ATOM   1167 O  OD2 . ASP   B 1 48  ? -3.150  -11.179 -33.231 1.000 88.910  0  158 ASP   A OD2 1 ? 
ATOM   1168 N  N   . ILE   B 1 49  ? -5.833  -14.322 -30.879 1.000 61.094  0  159 ILE   A N   1 ? 
ATOM   1169 C  CA  . ILE   B 1 49  ? -6.331  -15.688 -30.958 1.000 55.081  0  159 ILE   A CA  1 ? 
ATOM   1170 C  C   . ILE   B 1 49  ? -6.316  -16.169 -32.413 1.000 69.391  0  159 ILE   A C   1 ? 
ATOM   1171 O  O   . ILE   B 1 49  ? -6.951  -17.170 -32.741 1.000 72.649  0  159 ILE   A O   1 ? 
ATOM   1172 C  CB  . ILE   B 1 49  ? -7.730  -15.806 -30.323 1.000 50.785  0  159 ILE   A CB  1 ? 
ATOM   1173 C  CG1 . ILE   B 1 49  ? -8.767  -14.941 -31.052 1.000 47.521  0  159 ILE   A CG1 1 ? 
ATOM   1174 C  CG2 . ILE   B 1 49  ? -7.669  -15.483 -28.828 1.000 51.352  0  159 ILE   A CG2 1 ? 
ATOM   1175 C  CD1 . ILE   B 1 49  ? -10.204 -15.238 -30.664 1.000 47.608  0  159 ILE   A CD1 1 ? 
ATOM   1176 N  N   . ARG   B 1 50  ? -5.588  -15.453 -33.277 1.000 75.207  0  160 ARG   A N   1 ? 
ATOM   1177 C  CA  . ARG   B 1 50  ? -5.269  -15.961 -34.600 1.000 71.982  0  160 ARG   A CA  1 ? 
ATOM   1178 C  C   . ARG   B 1 50  ? -4.205  -17.046 -34.446 1.000 81.719  0  160 ARG   A C   1 ? 
ATOM   1179 O  O   . ARG   B 1 50  ? -3.263  -16.879 -33.674 1.000 94.807  0  160 ARG   A O   1 ? 
ATOM   1180 C  CB  . ARG   B 1 50  ? -4.748  -14.851 -35.522 1.000 72.580  0  160 ARG   A CB  1 ? 
ATOM   1181 C  CG  . ARG   B 1 50  ? -5.667  -13.647 -35.673 1.000 71.213  0  160 ARG   A CG  1 ? 
ATOM   1182 C  CD  . ARG   B 1 50  ? -5.079  -12.592 -36.612 1.000 74.714  0  160 ARG   A CD  1 ? 
ATOM   1183 N  NE  . ARG   B 1 50  ? -3.780  -12.083 -36.147 1.000 76.177  0  160 ARG   A NE  1 ? 
ATOM   1184 C  CZ  . ARG   B 1 50  ? -2.639  -12.090 -36.854 1.000 84.292  0  160 ARG   A CZ  1 ? 
ATOM   1185 N  NH1 . ARG   B 1 50  ? -2.622  -12.546 -38.098 1.000 84.257  0  160 ARG   A NH1 1 ? 
ATOM   1186 N  NH2 . ARG   B 1 50  ? -1.524  -11.618 -36.316 1.000 85.605  0  160 ARG   A NH2 1 ? 
ATOM   1187 N  N   . THR   B 1 51  ? -4.422  -18.188 -35.115 1.000 77.871  0  161 THR   A N   1 ? 
ATOM   1188 C  CA  . THR   B 1 51  ? -3.443  -19.276 -35.193 1.000 86.053  0  161 THR   A CA  1 ? 
ATOM   1189 C  C   . THR   B 1 51  ? -3.570  -20.217 -33.980 1.000 80.645  0  161 THR   A C   1 ? 
ATOM   1190 O  O   . THR   B 1 51  ? -2.776  -21.148 -33.847 1.000 85.696  0  161 THR   A O   1 ? 
ATOM   1191 C  CB  . THR   B 1 51  ? -2.008  -18.732 -35.325 1.000 80.714  0  161 THR   A CB  1 ? 
ATOM   1192 O  OG1 . THR   B 1 51  ? -1.646  -18.146 -34.079 1.000 75.055  0  161 THR   A OG1 1 ? 
ATOM   1193 C  CG2 . THR   B 1 51  ? -1.852  -17.726 -36.454 1.000 79.465  0  161 THR   A CG2 1 ? 
ATOM   1194 N  N   . ILE   B 1 52  ? -4.585  -20.004 -33.118 1.000 70.322  0  162 ILE   A N   1 ? 
ATOM   1195 C  CA  . ILE   B 1 52  ? -4.809  -20.908 -31.990 1.000 63.830  0  162 ILE   A CA  1 ? 
ATOM   1196 C  C   . ILE   B 1 52  ? -5.503  -22.168 -32.505 1.000 51.762  0  162 ILE   A C   1 ? 
ATOM   1197 O  O   . ILE   B 1 52  ? -6.131  -22.148 -33.563 1.000 40.482  0  162 ILE   A O   1 ? 
ATOM   1198 C  CB  . ILE   B 1 52  ? -5.610  -20.240 -30.850 1.000 72.266  0  162 ILE   A CB  1 ? 
ATOM   1199 C  CG1 . ILE   B 1 52  ? -7.091  -20.031 -31.224 1.000 69.506  0  162 ILE   A CG1 1 ? 
ATOM   1200 C  CG2 . ILE   B 1 52  ? -4.939  -18.940 -30.400 1.000 77.198  0  162 ILE   A CG2 1 ? 
ATOM   1201 C  CD1 . ILE   B 1 52  ? -7.979  -19.650 -30.052 1.000 70.523  0  162 ILE   A CD1 1 ? 
ATOM   1202 N  N   . GLU   B 1 53  ? -5.434  -23.238 -31.706 1.000 53.428  0  163 GLU   A N   1 ? 
ATOM   1203 C  CA  . GLU   B 1 53  ? -5.983  -24.531 -32.088 1.000 56.649  0  163 GLU   A CA  1 ? 
ATOM   1204 C  C   . GLU   B 1 53  ? -7.512  -24.459 -32.055 1.000 52.245  0  163 GLU   A C   1 ? 
ATOM   1205 O  O   . GLU   B 1 53  ? -8.084  -23.677 -31.300 1.000 50.300  0  163 GLU   A O   1 ? 
ATOM   1206 C  CB  . GLU   B 1 53  ? -5.468  -25.634 -31.153 1.000 71.628  0  163 GLU   A CB  1 ? 
ATOM   1207 C  CG  . GLU   B 1 53  ? -3.956  -25.594 -30.910 1.000 84.427  0  163 GLU   A CG  1 ? 
ATOM   1208 C  CD  . GLU   B 1 53  ? -3.081  -25.691 -32.154 1.000 101.333 0  163 GLU   A CD  1 ? 
ATOM   1209 O  OE1 . GLU   B 1 53  ? -3.614  -25.941 -33.256 1.000 117.335 0  163 GLU   A OE1 1 ? 
ATOM   1210 O  OE2 . GLU   B 1 53  ? -1.853  -25.496 -32.016 1.000 93.547  0  163 GLU   A OE2 1 ? 
ATOM   1211 N  N   . ASP   B 1 54  ? -8.159  -25.306 -32.872 1.000 49.836  0  164 ASP   A N   1 ? 
ATOM   1212 C  CA  . ASP   B 1 54  ? -9.614  -25.348 -32.964 1.000 47.429  0  164 ASP   A CA  1 ? 
ATOM   1213 C  C   . ASP   B 1 54  ? -10.220 -25.707 -31.605 1.000 44.614  0  164 ASP   A C   1 ? 
ATOM   1214 O  O   . ASP   B 1 54  ? -11.292 -25.213 -31.258 1.000 46.230  0  164 ASP   A O   1 ? 
ATOM   1215 C  CB  . ASP   B 1 54  ? -10.077 -26.304 -34.056 1.000 51.319  0  164 ASP   A CB  1 ? 
ATOM   1216 C  CG  . ASP   B 1 54  ? -10.126 -25.725 -35.465 1.000 59.163  0  164 ASP   A CG  1 ? 
ATOM   1217 O  OD1 . ASP   B 1 54  ? -9.929  -24.500 -35.606 1.000 76.460  0  164 ASP   A OD1 1 ? 
ATOM   1218 O  OD2 . ASP   B 1 54  ? -10.382 -26.503 -36.409 1.000 64.768  0  164 ASP   A OD2 1 ? 
ATOM   1219 N  N   . SER   B 1 55  ? -9.531  -26.576 -30.853 1.000 39.205  0  165 SER   A N   1 ? 
ATOM   1220 C  CA  . SER   B 1 55  ? -9.989  -26.995 -29.532 1.000 47.325  0  165 SER   A CA  1 ? 
ATOM   1221 C  C   . SER   B 1 55  ? -10.269 -25.775 -28.645 1.000 43.326  0  165 SER   A C   1 ? 
ATOM   1222 O  O   . SER   B 1 55  ? -11.330 -25.683 -28.032 1.000 38.202  0  165 SER   A O   1 ? 
ATOM   1223 C  CB  . SER   B 1 55  ? -8.989  -27.924 -28.877 1.000 48.241  0  165 SER   A CB  1 ? 
ATOM   1224 O  OG  . SER   B 1 55  ? -8.933  -29.172 -29.555 1.000 57.731  0  165 SER   A OG  1 ? 
ATOM   1225 N  N   . LYS   B 1 56  ? -9.306  -24.846 -28.589 1.000 41.911  0  166 LYS   A N   1 ? 
ATOM   1226 C  CA  . LYS   B 1 56  ? -9.399  -23.690 -27.708 1.000 42.774  0  166 LYS   A CA  1 ? 
ATOM   1227 C  C   . LYS   B 1 56  ? -10.340 -22.640 -28.304 1.000 41.526  0  166 LYS   A C   1 ? 
ATOM   1228 O  O   . LYS   B 1 56  ? -11.062 -21.972 -27.569 1.000 45.364  0  166 LYS   A O   1 ? 
ATOM   1229 C  CB  . LYS   B 1 56  ? -8.009  -23.125 -27.402 1.000 49.655  0  166 LYS   A CB  1 ? 
ATOM   1230 C  CG  . LYS   B 1 56  ? -7.240  -23.902 -26.341 1.000 54.294  0  166 LYS   A CG  1 ? 
ATOM   1231 C  CD  . LYS   B 1 56  ? -5.863  -23.340 -26.030 1.000 59.335  0  166 LYS   A CD  1 ? 
ATOM   1232 C  CE  . LYS   B 1 56  ? -5.227  -24.015 -24.862 1.000 57.205  0  166 LYS   A CE  1 ? 
ATOM   1233 N  NZ  . LYS   B 1 56  ? -3.909  -23.450 -24.567 1.000 63.526  0  166 LYS   A NZ  1 ? 
ATOM   1234 N  N   . LEU   B 1 57  ? -10.340 -22.509 -29.636 1.000 42.414  0  167 LEU   A N   1 ? 
ATOM   1235 C  CA  . LEU   B 1 57  ? -11.233 -21.568 -30.303 1.000 46.009  0  167 LEU   A CA  1 ? 
ATOM   1236 C  C   . LEU   B 1 57  ? -12.689 -21.984 -30.056 1.000 38.525  0  167 LEU   A C   1 ? 
ATOM   1237 O  O   . LEU   B 1 57  ? -13.564 -21.134 -29.914 1.000 34.852  0  167 LEU   A O   1 ? 
ATOM   1238 C  CB  . LEU   B 1 57  ? -10.920 -21.475 -31.797 1.000 47.171  0  167 LEU   A CB  1 ? 
ATOM   1239 C  CG  . LEU   B 1 57  ? -11.792 -20.503 -32.604 1.000 54.226  0  167 LEU   A CG  1 ? 
ATOM   1240 C  CD1 . LEU   B 1 57  ? -11.709 -19.086 -32.043 1.000 52.373  0  167 LEU   A CD1 1 ? 
ATOM   1241 C  CD2 . LEU   B 1 57  ? -11.413 -20.515 -34.071 1.000 56.230  0  167 LEU   A CD2 1 ? 
ATOM   1242 N  N   . ARG   B 1 58  ? -12.930 -23.301 -30.006 1.000 38.518  0  168 ARG   A N   1 ? 
ATOM   1243 C  CA  . ARG   B 1 58  ? -14.256 -23.833 -29.731 1.000 36.767  0  168 ARG   A CA  1 ? 
ATOM   1244 C  C   . ARG   B 1 58  ? -14.639 -23.538 -28.281 1.000 33.198  0  168 ARG   A C   1 ? 
ATOM   1245 O  O   . ARG   B 1 58  ? -15.794 -23.232 -27.990 1.000 34.154  0  168 ARG   A O   1 ? 
ATOM   1246 C  CB  . ARG   B 1 58  ? -14.307 -25.343 -29.992 1.000 37.138  0  168 ARG   A CB  1 ? 
ATOM   1247 C  CG  . ARG   B 1 58  ? -15.684 -25.965 -29.784 1.000 36.436  0  168 ARG   A CG  1 ? 
ATOM   1248 C  CD  . ARG   B 1 58  ? -16.718 -25.408 -30.758 1.000 37.002  0  168 ARG   A CD  1 ? 
ATOM   1249 N  NE  . ARG   B 1 58  ? -18.060 -25.973 -30.564 1.000 39.709  0  168 ARG   A NE  1 ? 
ATOM   1250 C  CZ  . ARG   B 1 58  ? -18.864 -25.719 -29.528 1.000 39.253  0  168 ARG   A CZ  1 ? 
ATOM   1251 N  NH1 . ARG   B 1 58  ? -18.477 -24.899 -28.564 1.000 41.296  0  168 ARG   A NH1 1 ? 
ATOM   1252 N  NH2 . ARG   B 1 58  ? -20.058 -26.282 -29.468 1.000 35.130  0  168 ARG   A NH2 1 ? 
ATOM   1253 N  N   . ALA   B 1 59  ? -13.666 -23.682 -27.375 1.000 34.281  0  169 ALA   A N   1 ? 
ATOM   1254 C  CA  . ALA   B 1 59  ? -13.889 -23.430 -25.962 1.000 33.788  0  169 ALA   A CA  1 ? 
ATOM   1255 C  C   . ALA   B 1 59  ? -14.223 -21.955 -25.739 1.000 33.533  0  169 ALA   A C   1 ? 
ATOM   1256 O  O   . ALA   B 1 59  ? -15.043 -21.629 -24.881 1.000 38.185  0  169 ALA   A O   1 ? 
ATOM   1257 C  CB  . ALA   B 1 59  ? -12.676 -23.853 -25.164 1.000 37.326  0  169 ALA   A CB  1 ? 
ATOM   1258 N  N   . LEU   B 1 60  ? -13.566 -21.068 -26.510 1.000 31.447  0  170 LEU   A N   1 ? 
ATOM   1259 C  CA  . LEU   B 1 60  ? -13.802 -19.630 -26.409 1.000 32.912  0  170 LEU   A CA  1 ? 
ATOM   1260 C  C   . LEU   B 1 60  ? -15.244 -19.313 -26.799 1.000 30.300  0  170 LEU   A C   1 ? 
ATOM   1261 O  O   . LEU   B 1 60  ? -15.852 -18.417 -26.223 1.000 30.587  0  170 LEU   A O   1 ? 
ATOM   1262 C  CB  . LEU   B 1 60  ? -12.808 -18.839 -27.267 1.000 36.636  0  170 LEU   A CB  1 ? 
ATOM   1263 C  CG  . LEU   B 1 60  ? -11.392 -18.677 -26.696 1.000 34.234  0  170 LEU   A CG  1 ? 
ATOM   1264 C  CD1 . LEU   B 1 60  ? -10.470 -18.050 -27.726 1.000 33.059  0  170 LEU   A CD1 1 ? 
ATOM   1265 C  CD2 . LEU   B 1 60  ? -11.395 -17.847 -25.420 1.000 34.128  0  170 LEU   A CD2 1 ? 
ATOM   1266 N  N   . LEU   B 1 61  ? -15.769 -20.029 -27.809 1.000 30.415  0  171 LEU   A N   1 ? 
ATOM   1267 C  CA  . LEU   B 1 61  ? -17.152 -19.846 -28.233 1.000 30.665  0  171 LEU   A CA  1 ? 
ATOM   1268 C  C   . LEU   B 1 61  ? -18.084 -20.243 -27.085 1.000 33.627  0  171 LEU   A C   1 ? 
ATOM   1269 O  O   . LEU   B 1 61  ? -19.099 -19.585 -26.853 1.000 32.564  0  171 LEU   A O   1 ? 
ATOM   1270 C  CB  . LEU   B 1 61  ? -17.455 -20.645 -29.501 1.000 33.217  0  171 LEU   A CB  1 ? 
ATOM   1271 C  CG  . LEU   B 1 61  ? -18.899 -20.553 -30.024 1.000 36.718  0  171 LEU   A CG  1 ? 
ATOM   1272 C  CD1 . LEU   B 1 61  ? -19.286 -19.119 -30.352 1.000 37.318  0  171 LEU   A CD1 1 ? 
ATOM   1273 C  CD2 . LEU   B 1 61  ? -19.090 -21.437 -31.234 1.000 38.279  0  171 LEU   A CD2 1 ? 
ATOM   1274 N  N   . THR   B 1 62  ? -17.721 -21.323 -26.369 1.000 33.183  0  172 THR   A N   1 ? 
ATOM   1275 C  CA  . THR   B 1 62  ? -18.471 -21.766 -25.198 1.000 33.482  0  172 THR   A CA  1 ? 
ATOM   1276 C  C   . THR   B 1 62  ? -18.445 -20.667 -24.128 1.000 30.772  0  172 THR   A C   1 ? 
ATOM   1277 O  O   . THR   B 1 62  ? -19.456 -20.402 -23.485 1.000 28.145  0  172 THR   A O   1 ? 
ATOM   1278 C  CB  . THR   B 1 62  ? -17.884 -23.078 -24.672 1.000 33.744  0  172 THR   A CB  1 ? 
ATOM   1279 O  OG1 . THR   B 1 62  ? -17.872 -23.968 -25.783 1.000 37.561  0  172 THR   A OG1 1 ? 
ATOM   1280 C  CG2 . THR   B 1 62  ? -18.694 -23.670 -23.534 1.000 38.312  0  172 THR   A CG2 1 ? 
ATOM   1281 N  N   . LEU   B 1 63  ? -17.272 -20.041 -23.943 1.000 29.042  0  173 LEU   A N   1 ? 
ATOM   1282 C  CA  . LEU   B 1 63  ? -17.106 -18.982 -22.955 1.000 30.981  0  173 LEU   A CA  1 ? 
ATOM   1283 C  C   . LEU   B 1 63  ? -18.046 -17.825 -23.284 1.000 30.573  0  173 LEU   A C   1 ? 
ATOM   1284 O  O   . LEU   B 1 63  ? -18.718 -17.301 -22.398 1.000 28.886  0  173 LEU   A O   1 ? 
ATOM   1285 C  CB  . LEU   B 1 63  ? -15.646 -18.528 -22.917 1.000 33.478  0  173 LEU   A CB  1 ? 
ATOM   1286 C  CG  . LEU   B 1 63  ? -15.303 -17.439 -21.895 1.000 34.919  0  173 LEU   A CG  1 ? 
ATOM   1287 C  CD1 . LEU   B 1 63  ? -15.541 -17.912 -20.479 1.000 35.048  0  173 LEU   A CD1 1 ? 
ATOM   1288 C  CD2 . LEU   B 1 63  ? -13.868 -16.976 -22.070 1.000 38.608  0  173 LEU   A CD2 1 ? 
ATOM   1289 N  N   . CYS   B 1 64  ? -18.100 -17.456 -24.573 1.000 31.286  0  174 CYS   A N   1 ? 
ATOM   1290 C  CA  . CYS   B 1 64  ? -18.957 -16.371 -25.036 1.000 35.782  0  174 CYS   A CA  1 ? 
ATOM   1291 C  C   . CYS   B 1 64  ? -20.431 -16.683 -24.740 1.000 32.265  0  174 CYS   A C   1 ? 
ATOM   1292 O  O   . CYS   B 1 64  ? -21.169 -15.815 -24.284 1.000 33.585  0  174 CYS   A O   1 ? 
ATOM   1293 C  CB  . CYS   B 1 64  ? -18.740 -16.097 -26.520 1.000 39.216  0  174 CYS   A CB  1 ? 
ATOM   1294 S  SG  . CYS   B 1 64  ? -17.087 -15.456 -26.898 1.000 43.478  0  174 CYS   A SG  1 ? 
ATOM   1295 N  N   . ALA   B 1 65  ? -20.838 -17.934 -24.987 1.000 33.977  0  175 ALA   A N   1 ? 
ATOM   1296 C  CA  . ALA   B 1 65  ? -22.221 -18.355 -24.786 1.000 33.769  0  175 ALA   A CA  1 ? 
ATOM   1297 C  C   . ALA   B 1 65  ? -22.590 -18.278 -23.303 1.000 36.583  0  175 ALA   A C   1 ? 
ATOM   1298 O  O   . ALA   B 1 65  ? -23.642 -17.742 -22.946 1.000 34.623  0  175 ALA   A O   1 ? 
ATOM   1299 C  CB  . ALA   B 1 65  ? -22.416 -19.751 -25.328 1.000 32.099  0  175 ALA   A CB  1 ? 
ATOM   1300 N  N   . VAL   B 1 66  ? -21.717 -18.829 -22.450 1.000 34.175  0  176 VAL   A N   1 ? 
ATOM   1301 C  CA  . VAL   B 1 66  ? -21.947 -18.850 -21.013 1.000 32.573  0  176 VAL   A CA  1 ? 
ATOM   1302 C  C   . VAL   B 1 66  ? -21.972 -17.412 -20.489 1.000 32.720  0  176 VAL   A C   1 ? 
ATOM   1303 O  O   . VAL   B 1 66  ? -22.849 -17.051 -19.709 1.000 33.363  0  176 VAL   A O   1 ? 
ATOM   1304 C  CB  . VAL   B 1 66  ? -20.879 -19.700 -20.294 1.000 34.942  0  176 VAL   A CB  1 ? 
ATOM   1305 C  CG1 . VAL   B 1 66  ? -20.930 -19.524 -18.781 1.000 37.365  0  176 VAL   A CG1 1 ? 
ATOM   1306 C  CG2 . VAL   B 1 66  ? -20.989 -21.176 -20.667 1.000 33.213  0  176 VAL   A CG2 1 ? 
ATOM   1307 N  N   . MET   B 1 67  ? -21.011 -16.600 -20.950 1.000 34.518  0  177 MET   A N   1 ? 
ATOM   1308 C  CA  . MET   B 1 67  ? -20.898 -15.205 -20.539 1.000 36.936  0  177 MET   A CA  1 ? 
ATOM   1309 C  C   . MET   B 1 67  ? -22.149 -14.424 -20.958 1.000 35.677  0  177 MET   A C   1 ? 
ATOM   1310 O  O   . MET   B 1 67  ? -22.612 -13.555 -20.222 1.000 31.493  0  177 MET   A O   1 ? 
ATOM   1311 C  CB  . MET   B 1 67  ? -19.657 -14.563 -21.159 1.000 39.751  0  177 MET   A CB  1 ? 
ATOM   1312 C  CG  . MET   B 1 67  ? -18.356 -14.965 -20.492 1.000 51.111  0  177 MET   A CG  1 ? 
ATOM   1313 S  SD  . MET   B 1 67  ? -17.975 -13.964 -19.042 1.000 72.941  0  177 MET   A SD  1 ? 
ATOM   1314 C  CE  . MET   B 1 67  ? -17.461 -12.442 -19.853 1.000 68.079  0  177 MET   A CE  1 ? 
ATOM   1315 N  N   . THR   B 1 68  ? -22.695 -14.755 -22.141 1.000 32.188  0  178 THR   A N   1 ? 
ATOM   1316 C  CA  . THR   B 1 68  ? -23.869 -14.073 -22.676 1.000 32.864  0  178 THR   A CA  1 ? 
ATOM   1317 C  C   . THR   B 1 68  ? -25.061 -14.263 -21.733 1.000 30.364  0  178 THR   A C   1 ? 
ATOM   1318 O  O   . THR   B 1 68  ? -25.846 -13.338 -21.532 1.000 25.819  0  178 THR   A O   1 ? 
ATOM   1319 C  CB  . THR   B 1 68  ? -24.174 -14.599 -24.081 1.000 37.706  0  178 THR   A CB  1 ? 
ATOM   1320 O  OG1 . THR   B 1 68  ? -23.116 -14.117 -24.905 1.000 35.907  0  178 THR   A OG1 1 ? 
ATOM   1321 C  CG2 . THR   B 1 68  ? -25.505 -14.102 -24.620 1.000 39.354  0  178 THR   A CG2 1 ? 
ATOM   1322 N  N   . ARG   B 1 69  ? -25.171 -15.467 -21.143 1.000 32.152  0  179 ARG   A N   1 ? 
ATOM   1323 C  CA  . ARG   B 1 69  ? -26.306 -15.819 -20.297 1.000 31.906  0  179 ARG   A CA  1 ? 
ATOM   1324 C  C   . ARG   B 1 69  ? -26.126 -15.263 -18.877 1.000 33.111  0  179 ARG   A C   1 ? 
ATOM   1325 O  O   . ARG   B 1 69  ? -26.961 -15.514 -18.015 1.000 37.264  0  179 ARG   A O   1 ? 
ATOM   1326 C  CB  . ARG   B 1 69  ? -26.514 -17.341 -20.264 1.000 31.298  0  179 ARG   A CB  1 ? 
ATOM   1327 C  CG  . ARG   B 1 69  ? -27.044 -17.909 -21.572 1.000 31.500  0  179 ARG   A CG  1 ? 
ATOM   1328 C  CD  . ARG   B 1 69  ? -27.500 -19.353 -21.446 1.000 30.622  0  179 ARG   A CD  1 ? 
ATOM   1329 N  NE  . ARG   B 1 69  ? -26.396 -20.307 -21.293 1.000 31.093  0  179 ARG   A NE  1 ? 
ATOM   1330 C  CZ  . ARG   B 1 69  ? -25.589 -20.735 -22.268 1.000 31.253  0  179 ARG   A CZ  1 ? 
ATOM   1331 N  NH1 . ARG   B 1 69  ? -25.754 -20.317 -23.515 1.000 38.600  0  179 ARG   A NH1 1 ? 
ATOM   1332 N  NH2 . ARG   B 1 69  ? -24.643 -21.617 -21.995 1.000 32.964  0  179 ARG   A NH2 1 ? 
ATOM   1333 N  N   . LYS   B 1 70  ? -25.024 -14.527 -18.637 1.000 32.138  0  180 LYS   A N   1 ? 
ATOM   1334 C  CA  . LYS   B 1 70  ? -24.827 -13.836 -17.367 1.000 33.100  0  180 LYS   A CA  1 ? 
ATOM   1335 C  C   . LYS   B 1 70  ? -25.367 -12.407 -17.469 1.000 36.114  0  180 LYS   A C   1 ? 
ATOM   1336 O  O   . LYS   B 1 70  ? -25.373 -11.677 -16.483 1.000 33.344  0  180 LYS   A O   1 ? 
ATOM   1337 C  CB  . LYS   B 1 70  ? -23.352 -13.845 -16.946 1.000 33.626  0  180 LYS   A CB  1 ? 
ATOM   1338 C  CG  . LYS   B 1 70  ? -22.700 -15.223 -16.905 1.000 34.258  0  180 LYS   A CG  1 ? 
ATOM   1339 C  CD  . LYS   B 1 70  ? -23.449 -16.250 -16.061 1.000 34.210  0  180 LYS   A CD  1 ? 
ATOM   1340 C  CE  . LYS   B 1 70  ? -22.932 -17.631 -16.253 1.000 36.067  0  180 LYS   A CE  1 ? 
ATOM   1341 N  NZ  . LYS   B 1 70  ? -23.735 -18.615 -15.523 1.000 40.987  0  180 LYS   A NZ  1 ? 
ATOM   1342 N  N   . PHE   B 1 71  ? -25.787 -12.010 -18.682 1.000 39.424  0  181 PHE   A N   1 ? 
ATOM   1343 C  CA  . PHE   B 1 71  ? -26.449 -10.732 -18.895 1.000 41.721  0  181 PHE   A CA  1 ? 
ATOM   1344 C  C   . PHE   B 1 71  ? -27.957 -10.943 -18.844 1.000 39.142  0  181 PHE   A C   1 ? 
ATOM   1345 O  O   . PHE   B 1 71  ? -28.458 -11.966 -19.301 1.000 33.603  0  181 PHE   A O   1 ? 
ATOM   1346 C  CB  . PHE   B 1 71  ? -26.046 -10.112 -20.240 1.000 42.668  0  181 PHE   A CB  1 ? 
ATOM   1347 C  CG  . PHE   B 1 71  ? -24.613 -9.609  -20.303 1.000 46.694  0  181 PHE   A CG  1 ? 
ATOM   1348 C  CD1 . PHE   B 1 71  ? -23.573 -10.458 -20.670 1.000 47.241  0  181 PHE   A CD1 1 ? 
ATOM   1349 C  CD2 . PHE   B 1 71  ? -24.308 -8.285  -19.999 1.000 50.217  0  181 PHE   A CD2 1 ? 
ATOM   1350 C  CE1 . PHE   B 1 71  ? -22.264 -9.999  -20.709 1.000 50.776  0  181 PHE   A CE1 1 ? 
ATOM   1351 C  CE2 . PHE   B 1 71  ? -22.996 -7.831  -20.047 1.000 53.493  0  181 PHE   A CE2 1 ? 
ATOM   1352 C  CZ  . PHE   B 1 71  ? -21.979 -8.689  -20.399 1.000 49.131  0  181 PHE   A CZ  1 ? 
ATOM   1353 N  N   . SER   B 1 72  ? -28.670 -9.963  -18.283 1.000 41.693  0  182 SER   A N   1 ? 
ATOM   1354 C  CA  . SER   B 1 72  ? -30.121 -9.953  -18.330 1.000 44.229  0  182 SER   A CA  1 ? 
ATOM   1355 C  C   . SER   B 1 72  ? -30.568 -9.806  -19.783 1.000 42.116  0  182 SER   A C   1 ? 
ATOM   1356 O  O   . SER   B 1 72  ? -29.911 -9.124  -20.569 1.000 37.435  0  182 SER   A O   1 ? 
ATOM   1357 C  CB  . SER   B 1 72  ? -30.694 -8.854  -17.463 1.000 42.424  0  182 SER   A CB  1 ? 
ATOM   1358 O  OG  . SER   B 1 72  ? -30.271 -7.574  -17.913 1.000 54.615  0  182 SER   A OG  1 ? 
ATOM   1359 N  N   . LYS   B 1 73  ? -31.689 -10.453 -20.127 1.000 34.919  0  183 LYS   A N   1 ? 
ATOM   1360 C  CA  . LYS   B 1 73  ? -32.225 -10.421 -21.484 1.000 40.480  0  183 LYS   A CA  1 ? 
ATOM   1361 C  C   . LYS   B 1 73  ? -32.357 -8.968  -21.969 1.000 30.564  0  183 LYS   A C   1 ? 
ATOM   1362 O  O   . LYS   B 1 73  ? -32.214 -8.693  -23.155 1.000 39.551  0  183 LYS   A O   1 ? 
ATOM   1363 C  CB  . LYS   B 1 73  ? -33.589 -11.120 -21.518 1.000 49.017  0  183 LYS   A CB  1 ? 
ATOM   1364 C  CG  . LYS   B 1 73  ? -34.230 -11.253 -22.903 1.000 67.438  0  183 LYS   A CG  1 ? 
ATOM   1365 C  CD  . LYS   B 1 73  ? -35.753 -11.329 -22.879 1.000 82.392  0  183 LYS   A CD  1 ? 
ATOM   1366 C  CE  . LYS   B 1 73  ? -36.387 -10.012 -22.513 1.000 93.713  0  183 LYS   A CE  1 ? 
ATOM   1367 N  NZ  . LYS   B 1 73  ? -37.843 -10.115 -22.405 1.000 105.108 0  183 LYS   A NZ  1 ? 
ATOM   1368 N  N   . SER   B 1 74  ? -32.595 -8.046  -21.029 1.000 31.387  0  184 SER   A N   1 ? 
ATOM   1369 C  CA  . SER   B 1 74  ? -32.850 -6.648  -21.350 1.000 35.098  0  184 SER   A CA  1 ? 
ATOM   1370 C  C   . SER   B 1 74  ? -31.560 -5.910  -21.758 1.000 41.809  0  184 SER   A C   1 ? 
ATOM   1371 O  O   . SER   B 1 74  ? -31.623 -4.752  -22.166 1.000 38.961  0  184 SER   A O   1 ? 
ATOM   1372 C  CB  . SER   B 1 74  ? -33.521 -5.955  -20.188 1.000 35.549  0  184 SER   A CB  1 ? 
ATOM   1373 O  OG  . SER   B 1 74  ? -32.725 -6.047  -19.011 1.000 42.641  0  184 SER   A OG  1 ? 
ATOM   1374 N  N   . GLN   B 1 75  ? -30.395 -6.578  -21.637 1.000 41.543  0  185 GLN   A N   1 ? 
ATOM   1375 C  CA  . GLN   B 1 75  ? -29.112 -5.949  -21.947 1.000 42.397  0  185 GLN   A CA  1 ? 
ATOM   1376 C  C   . GLN   B 1 75  ? -28.580 -6.414  -23.310 1.000 41.039  0  185 GLN   A C   1 ? 
ATOM   1377 O  O   . GLN   B 1 75  ? -27.555 -5.912  -23.770 1.000 38.558  0  185 GLN   A O   1 ? 
ATOM   1378 C  CB  . GLN   B 1 75  ? -28.077 -6.246  -20.855 1.000 41.003  0  185 GLN   A CB  1 ? 
ATOM   1379 C  CG  . GLN   B 1 75  ? -28.197 -5.362  -19.618 1.000 44.014  0  185 GLN   A CG  1 ? 
ATOM   1380 C  CD  . GLN   B 1 75  ? -27.846 -3.912  -19.886 1.000 46.220  0  185 GLN   A CD  1 ? 
ATOM   1381 O  OE1 . GLN   B 1 75  ? -28.612 -3.165  -20.503 1.000 54.448  0  185 GLN   A OE1 1 ? 
ATOM   1382 N  NE2 . GLN   B 1 75  ? -26.692 -3.491  -19.392 1.000 50.683  0  185 GLN   A NE2 1 ? 
ATOM   1383 N  N   . LEU   B 1 76  ? -29.292 -7.346  -23.966 1.000 33.321  0  186 LEU   A N   1 ? 
ATOM   1384 C  CA  . LEU   B 1 76  ? -28.814 -7.926  -25.221 1.000 38.059  0  186 LEU   A CA  1 ? 
ATOM   1385 C  C   . LEU   B 1 76  ? -28.788 -6.858  -26.321 1.000 37.948  0  186 LEU   A C   1 ? 
ATOM   1386 O  O   . LEU   B 1 76  ? -27.924 -6.889  -27.197 1.000 37.649  0  186 LEU   A O   1 ? 
ATOM   1387 C  CB  . LEU   B 1 76  ? -29.671 -9.124  -25.625 1.000 38.792  0  186 LEU   A CB  1 ? 
ATOM   1388 C  CG  . LEU   B 1 76  ? -29.609 -10.342 -24.695 1.000 43.526  0  186 LEU   A CG  1 ? 
ATOM   1389 C  CD1 . LEU   B 1 76  ? -30.422 -11.483 -25.272 1.000 41.631  0  186 LEU   A CD1 1 ? 
ATOM   1390 C  CD2 . LEU   B 1 76  ? -28.173 -10.790 -24.434 1.000 46.369  0  186 LEU   A CD2 1 ? 
ATOM   1391 N  N   . SER   B 1 77  ? -29.754 -5.932  -26.274 1.000 42.943  0  187 SER   A N   1 ? 
ATOM   1392 C  CA  . SER   B 1 77  ? -29.842 -4.851  -27.245 1.000 43.498  0  187 SER   A CA  1 ? 
ATOM   1393 C  C   . SER   B 1 77  ? -28.604 -3.949  -27.152 1.000 36.225  0  187 SER   A C   1 ? 
ATOM   1394 O  O   . SER   B 1 77  ? -28.037 -3.566  -28.171 1.000 32.857  0  187 SER   A O   1 ? 
ATOM   1395 C  CB  . SER   B 1 77  ? -31.112 -4.060  -27.055 1.000 43.011  0  187 SER   A CB  1 ? 
ATOM   1396 O  OG  . SER   B 1 77  ? -31.245 -3.060  -28.053 1.000 53.788  0  187 SER   A OG  1 ? 
ATOM   1397 N  N   . LEU   B 1 78  ? -28.196 -3.623  -25.917 1.000 37.594  0  188 LEU   A N   1 ? 
ATOM   1398 C  CA  . LEU   B 1 78  ? -27.031 -2.778  -25.680 1.000 35.140  0  188 LEU   A CA  1 ? 
ATOM   1399 C  C   . LEU   B 1 78  ? -25.759 -3.536  -26.075 1.000 35.569  0  188 LEU   A C   1 ? 
ATOM   1400 O  O   . LEU   B 1 78  ? -24.831 -2.948  -26.630 1.000 34.554  0  188 LEU   A O   1 ? 
ATOM   1401 C  CB  . LEU   B 1 78  ? -26.999 -2.349  -24.212 1.000 38.191  0  188 LEU   A CB  1 ? 
ATOM   1402 C  CG  . LEU   B 1 78  ? -25.884 -1.370  -23.816 1.000 48.403  0  188 LEU   A CG  1 ? 
ATOM   1403 C  CD1 . LEU   B 1 78  ? -26.058 -0.020  -24.505 1.000 51.300  0  188 LEU   A CD1 1 ? 
ATOM   1404 C  CD2 . LEU   B 1 78  ? -25.831 -1.196  -22.308 1.000 45.318  0  188 LEU   A CD2 1 ? 
ATOM   1405 N  N   . LEU   B 1 79  ? -25.721 -4.841  -25.758 1.000 36.249  0  189 LEU   A N   1 ? 
ATOM   1406 C  CA  . LEU   B 1 79  ? -24.594 -5.695  -26.108 1.000 37.174  0  189 LEU   A CA  1 ? 
ATOM   1407 C  C   . LEU   B 1 79  ? -24.412 -5.693  -27.627 1.000 43.393  0  189 LEU   A C   1 ? 
ATOM   1408 O  O   . LEU   B 1 79  ? -23.287 -5.598  -28.124 1.000 37.325  0  189 LEU   A O   1 ? 
ATOM   1409 C  CB  . LEU   B 1 79  ? -24.833 -7.107  -25.568 1.000 41.467  0  189 LEU   A CB  1 ? 
ATOM   1410 C  CG  . LEU   B 1 79  ? -23.749 -8.147  -25.876 1.000 50.529  0  189 LEU   A CG  1 ? 
ATOM   1411 C  CD1 . LEU   B 1 79  ? -22.416 -7.773  -25.246 1.000 52.921  0  189 LEU   A CD1 1 ? 
ATOM   1412 C  CD2 . LEU   B 1 79  ? -24.184 -9.523  -25.415 1.000 55.518  0  189 LEU   A CD2 1 ? 
ATOM   1413 N  N   . CYS   B 1 80  ? -25.535 -5.805  -28.352 1.000 44.427  0  190 CYS   A N   1 ? 
ATOM   1414 C  CA  . CYS   B 1 80  ? -25.531 -5.768  -29.806 1.000 40.978  0  190 CYS   A CA  1 ? 
ATOM   1415 C  C   . CYS   B 1 80  ? -24.986 -4.427  -30.292 1.000 38.547  0  190 CYS   A C   1 ? 
ATOM   1416 O  O   . CYS   B 1 80  ? -24.077 -4.389  -31.117 1.000 36.045  0  190 CYS   A O   1 ? 
ATOM   1417 C  CB  . CYS   B 1 80  ? -26.931 -6.004  -30.364 1.000 45.568  0  190 CYS   A CB  1 ? 
ATOM   1418 S  SG  . CYS   B 1 80  ? -27.052 -5.738  -32.154 1.000 40.298  0  190 CYS   A SG  1 ? 
ATOM   1419 N  N   . GLU   B 1 81  ? -25.545 -3.332  -29.756 1.000 37.000  0  191 GLU   A N   1 ? 
ATOM   1420 C  CA  . GLU   B 1 81  ? -25.196 -1.988  -30.195 1.000 36.404  0  191 GLU   A CA  1 ? 
ATOM   1421 C  C   . GLU   B 1 81  ? -23.702 -1.752  -29.975 1.000 37.877  0  191 GLU   A C   1 ? 
ATOM   1422 O  O   . GLU   B 1 81  ? -23.011 -1.268  -30.867 1.000 40.172  0  191 GLU   A O   1 ? 
ATOM   1423 C  CB  . GLU   B 1 81  ? -26.026 -0.944  -29.446 1.000 42.800  0  191 GLU   A CB  1 ? 
ATOM   1424 C  CG  . GLU   B 1 81  ? -26.055 0.424   -30.130 1.000 49.854  0  191 GLU   A CG  1 ? 
ATOM   1425 C  CD  . GLU   B 1 81  ? -26.907 0.489   -31.395 1.000 62.184  0  191 GLU   A CD  1 ? 
ATOM   1426 O  OE1 . GLU   B 1 81  ? -27.553 -0.528  -31.745 1.000 63.290  0  191 GLU   A OE1 1 ? 
ATOM   1427 O  OE2 . GLU   B 1 81  ? -26.932 1.568   -32.026 1.000 71.159  0  191 GLU   A OE2 1 ? 
ATOM   1428 N  N   . THR   B 1 82  ? -23.212 -2.129  -28.784 1.000 33.581  0  192 THR   A N   1 ? 
ATOM   1429 C  CA  . THR   B 1 82  ? -21.817 -1.922  -28.415 1.000 32.310  0  192 THR   A CA  1 ? 
ATOM   1430 C  C   . THR   B 1 82  ? -20.913 -2.742  -29.340 1.000 34.027  0  192 THR   A C   1 ? 
ATOM   1431 O  O   . THR   B 1 82  ? -19.816 -2.308  -29.680 1.000 35.223  0  192 THR   A O   1 ? 
ATOM   1432 C  CB  . THR   B 1 82  ? -21.616 -2.298  -26.949 1.000 32.373  0  192 THR   A CB  1 ? 
ATOM   1433 O  OG1 . THR   B 1 82  ? -22.591 -1.551  -26.229 1.000 34.901  0  192 THR   A OG1 1 ? 
ATOM   1434 C  CG2 . THR   B 1 82  ? -20.223 -1.965  -26.445 1.000 29.462  0  192 THR   A CG2 1 ? 
ATOM   1435 N  N   . HIS   B 1 83  ? -21.384 -3.936  -29.724 1.000 31.281  0  193 HIS   A N   1 ? 
ATOM   1436 C  CA  . HIS   B 1 83  ? -20.647 -4.812  -30.624 1.000 34.255  0  193 HIS   A CA  1 ? 
ATOM   1437 C  C   . HIS   B 1 83  ? -20.451 -4.117  -31.977 1.000 39.651  0  193 HIS   A C   1 ? 
ATOM   1438 O  O   . HIS   B 1 83  ? -19.328 -4.031  -32.471 1.000 40.119  0  193 HIS   A O   1 ? 
ATOM   1439 C  CB  . HIS   B 1 83  ? -21.364 -6.165  -30.748 1.000 33.025  0  193 HIS   A CB  1 ? 
ATOM   1440 C  CG  . HIS   B 1 83  ? -20.632 -7.198  -31.539 1.000 31.033  0  193 HIS   A CG  1 ? 
ATOM   1441 N  ND1 . HIS   B 1 83  ? -20.437 -8.472  -31.056 1.000 29.288  0  193 HIS   A ND1 1 ? 
ATOM   1442 C  CD2 . HIS   B 1 83  ? -20.010 -7.157  -32.727 1.000 34.365  0  193 HIS   A CD2 1 ? 
ATOM   1443 C  CE1 . HIS   B 1 83  ? -19.763 -9.178  -31.947 1.000 30.633  0  193 HIS   A CE1 1 ? 
ATOM   1444 N  NE2 . HIS   B 1 83  ? -19.495 -8.402  -32.969 1.000 30.223  0  193 HIS   A NE2 1 ? 
ATOM   1445 N  N   . LEU   B 1 84  ? -21.553 -3.593  -32.546 1.000 40.262  0  194 LEU   A N   1 ? 
ATOM   1446 C  CA  . LEU   B 1 84  ? -21.538 -2.973  -33.873 1.000 40.748  0  194 LEU   A CA  1 ? 
ATOM   1447 C  C   . LEU   B 1 84  ? -20.531 -1.822  -33.900 1.000 39.163  0  194 LEU   A C   1 ? 
ATOM   1448 O  O   . LEU   B 1 84  ? -19.746 -1.702  -34.837 1.000 33.497  0  194 LEU   A O   1 ? 
ATOM   1449 C  CB  . LEU   B 1 84  ? -22.937 -2.471  -34.239 1.000 40.850  0  194 LEU   A CB  1 ? 
ATOM   1450 C  CG  . LEU   B 1 84  ? -24.050 -3.523  -34.294 1.000 42.269  0  194 LEU   A CG  1 ? 
ATOM   1451 C  CD1 . LEU   B 1 84  ? -25.398 -2.839  -34.397 1.000 44.915  0  194 LEU   A CD1 1 ? 
ATOM   1452 C  CD2 . LEU   B 1 84  ? -23.856 -4.500  -35.441 1.000 40.397  0  194 LEU   A CD2 1 ? 
ATOM   1453 N  N   . ARG   B 1 85  ? -20.612 -0.951  -32.885 1.000 37.049  0  195 ARG   A N   1 ? 
ATOM   1454 C  CA  . ARG   B 1 85  ? -19.813 0.260   -32.831 1.000 38.640  0  195 ARG   A CA  1 ? 
ATOM   1455 C  C   . ARG   B 1 85  ? -18.324 -0.084  -32.761 1.000 35.906  0  195 ARG   A C   1 ? 
ATOM   1456 O  O   . ARG   B 1 85  ? -17.516 0.548   -33.427 1.000 36.071  0  195 ARG   A O   1 ? 
ATOM   1457 C  CB  . ARG   B 1 85  ? -20.247 1.128   -31.645 1.000 40.398  0  195 ARG   A CB  1 ? 
ATOM   1458 C  CG  . ARG   B 1 85  ? -21.631 1.758   -31.769 1.000 37.153  0  195 ARG   A CG  1 ? 
ATOM   1459 C  CD  . ARG   B 1 85  ? -21.747 2.725   -32.950 1.000 37.130  0  195 ARG   A CD  1 ? 
ATOM   1460 N  NE  . ARG   B 1 85  ? -22.130 2.064   -34.206 1.000 39.479  0  195 ARG   A NE  1 ? 
ATOM   1461 C  CZ  . ARG   B 1 85  ? -23.335 1.545   -34.464 1.000 34.873  0  195 ARG   A CZ  1 ? 
ATOM   1462 N  NH1 . ARG   B 1 85  ? -24.313 1.660   -33.582 1.000 35.435  0  195 ARG   A NH1 1 ? 
ATOM   1463 N  NH2 . ARG   B 1 85  ? -23.564 0.943   -35.621 1.000 39.812  0  195 ARG   A NH2 1 ? 
ATOM   1464 N  N   . ARG   B 1 86  ? -17.972 -1.096  -31.960 1.000 32.806  0  196 ARG   A N   1 ? 
ATOM   1465 C  CA  . ARG   B 1 86  ? -16.577 -1.480  -31.781 1.000 36.131  0  196 ARG   A CA  1 ? 
ATOM   1466 C  C   . ARG   B 1 86  ? -15.984 -1.948  -33.117 1.000 37.551  0  196 ARG   A C   1 ? 
ATOM   1467 O  O   . ARG   B 1 86  ? -14.859 -1.580  -33.461 1.000 33.725  0  196 ARG   A O   1 ? 
ATOM   1468 C  CB  . ARG   B 1 86  ? -16.427 -2.596  -30.744 1.000 36.952  0  196 ARG   A CB  1 ? 
ATOM   1469 C  CG  . ARG   B 1 86  ? -14.979 -2.848  -30.351 1.000 42.497  0  196 ARG   A CG  1 ? 
ATOM   1470 C  CD  . ARG   B 1 86  ? -14.744 -4.237  -29.819 1.000 43.681  0  196 ARG   A CD  1 ? 
ATOM   1471 N  NE  . ARG   B 1 86  ? -13.350 -4.387  -29.396 1.000 41.641  0  196 ARG   A NE  1 ? 
ATOM   1472 C  CZ  . ARG   B 1 86  ? -12.406 -5.051  -30.058 1.000 41.557  0  196 ARG   A CZ  1 ? 
ATOM   1473 N  NH1 . ARG   B 1 86  ? -12.682 -5.652  -31.205 1.000 44.671  0  196 ARG   A NH1 1 ? 
ATOM   1474 N  NH2 . ARG   B 1 86  ? -11.178 -5.095  -29.577 1.000 42.416  0  196 ARG   A NH2 1 ? 
ATOM   1475 N  N   . GLU   B 1 87  ? -16.758 -2.758  -33.858 1.000 35.575  0  197 GLU   A N   1 ? 
ATOM   1476 C  CA  . GLU   B 1 87  ? -16.273 -3.397  -35.075 1.000 35.705  0  197 GLU   A CA  1 ? 
ATOM   1477 C  C   . GLU   B 1 87  ? -16.471 -2.479  -36.282 1.000 35.552  0  197 GLU   A C   1 ? 
ATOM   1478 O  O   . GLU   B 1 87  ? -15.918 -2.739  -37.350 1.000 41.318  0  197 GLU   A O   1 ? 
ATOM   1479 C  CB  . GLU   B 1 87  ? -16.974 -4.738  -35.289 1.000 38.025  0  197 GLU   A CB  1 ? 
ATOM   1480 C  CG  . GLU   B 1 87  ? -16.741 -5.740  -34.161 1.000 41.265  0  197 GLU   A CG  1 ? 
ATOM   1481 C  CD  . GLU   B 1 87  ? -15.280 -5.943  -33.777 1.000 50.574  0  197 GLU   A CD  1 ? 
ATOM   1482 O  OE1 . GLU   B 1 87  ? -14.712 -6.995  -34.147 1.000 57.830  0  197 GLU   A OE1 1 ? 
ATOM   1483 O  OE2 . GLU   B 1 87  ? -14.738 -5.092  -33.030 1.000 58.028  0  197 GLU   A OE2 1 ? 
ATOM   1484 N  N   . GLY   B 1 88  ? -17.273 -1.420  -36.109 1.000 37.301  0  198 GLY   A N   1 ? 
ATOM   1485 C  CA  . GLY   B 1 88  ? -17.500 -0.442  -37.165 1.000 36.683  0  198 GLY   A CA  1 ? 
ATOM   1486 C  C   . GLY   B 1 88  ? -18.566 -0.917  -38.153 1.000 39.064  0  198 GLY   A C   1 ? 
ATOM   1487 O  O   . GLY   B 1 88  ? -18.515 -0.579  -39.334 1.000 37.873  0  198 GLY   A O   1 ? 
ATOM   1488 N  N   . LEU   B 1 89  ? -19.548 -1.677  -37.643 1.000 37.715  0  199 LEU   A N   1 ? 
ATOM   1489 C  CA  . LEU   B 1 89  ? -20.635 -2.194  -38.461 1.000 39.463  0  199 LEU   A CA  1 ? 
ATOM   1490 C  C   . LEU   B 1 89  ? -21.763 -1.165  -38.508 1.000 35.717  0  199 LEU   A C   1 ? 
ATOM   1491 O  O   . LEU   B 1 89  ? -21.953 -0.402  -37.562 1.000 35.903  0  199 LEU   A O   1 ? 
ATOM   1492 C  CB  . LEU   B 1 89  ? -21.126 -3.525  -37.885 1.000 45.064  0  199 LEU   A CB  1 ? 
ATOM   1493 C  CG  . LEU   B 1 89  ? -20.063 -4.612  -37.689 1.000 47.413  0  199 LEU   A CG  1 ? 
ATOM   1494 C  CD1 . LEU   B 1 89  ? -20.673 -5.847  -37.046 1.000 46.207  0  199 LEU   A CD1 1 ? 
ATOM   1495 C  CD2 . LEU   B 1 89  ? -19.386 -4.976  -38.999 1.000 42.954  0  199 LEU   A CD2 1 ? 
ATOM   1496 N  N   . GLY   B 1 90  ? -22.515 -1.168  -39.618 1.000 40.797  0  200 GLY   A N   1 ? 
ATOM   1497 C  CA  . GLY   B 1 90  ? -23.701 -0.333  -39.754 1.000 41.959  0  200 GLY   A CA  1 ? 
ATOM   1498 C  C   . GLY   B 1 90  ? -24.885 -0.936  -38.998 1.000 44.209  0  200 GLY   A C   1 ? 
ATOM   1499 O  O   . GLY   B 1 90  ? -24.841 -2.099  -38.598 1.000 48.117  0  200 GLY   A O   1 ? 
ATOM   1500 N  N   . GLN   B 1 91  ? -25.958 -0.140  -38.850 1.000 43.573  0  201 GLN   A N   1 ? 
ATOM   1501 C  CA  . GLN   B 1 91  ? -27.159 -0.567  -38.137 1.000 51.795  0  201 GLN   A CA  1 ? 
ATOM   1502 C  C   . GLN   B 1 91  ? -27.870 -1.690  -38.901 1.000 50.421  0  201 GLN   A C   1 ? 
ATOM   1503 O  O   . GLN   B 1 91  ? -28.702 -2.391  -38.332 1.000 60.943  0  201 GLN   A O   1 ? 
ATOM   1504 C  CB  . GLN   B 1 91  ? -28.119 0.605   -37.926 1.000 54.459  0  201 GLN   A CB  1 ? 
ATOM   1505 C  CG  . GLN   B 1 91  ? -27.639 1.626   -36.901 1.000 63.543  0  201 GLN   A CG  1 ? 
ATOM   1506 C  CD  . GLN   B 1 91  ? -27.434 1.034   -35.524 1.000 61.693  0  201 GLN   A CD  1 ? 
ATOM   1507 O  OE1 . GLN   B 1 91  ? -26.344 1.103   -34.953 1.000 62.537  0  201 GLN   A OE1 1 ? 
ATOM   1508 N  NE2 . GLN   B 1 91  ? -28.485 0.438   -34.980 1.000 58.258  0  201 GLN   A NE2 1 ? 
ATOM   1509 N  N   . ASP   B 1 92  ? -27.535 -1.849  -40.190 1.000 49.853  0  202 ASP   A N   1 ? 
ATOM   1510 C  CA  . ASP   B 1 92  ? -28.106 -2.904  -41.019 1.000 59.455  0  202 ASP   A CA  1 ? 
ATOM   1511 C  C   . ASP   B 1 92  ? -27.672 -4.288  -40.505 1.000 61.226  0  202 ASP   A C   1 ? 
ATOM   1512 O  O   . ASP   B 1 92  ? -28.255 -5.299  -40.890 1.000 65.761  0  202 ASP   A O   1 ? 
ATOM   1513 C  CB  . ASP   B 1 92  ? -27.755 -2.704  -42.491 1.000 64.504  0  202 ASP   A CB  1 ? 
ATOM   1514 C  CG  . ASP   B 1 92  ? -26.279 -2.469  -42.796 1.000 78.644  0  202 ASP   A CG  1 ? 
ATOM   1515 O  OD1 . ASP   B 1 92  ? -25.765 -1.390  -42.424 1.000 88.222  0  202 ASP   A OD1 1 ? 
ATOM   1516 O  OD2 . ASP   B 1 92  ? -25.653 -3.370  -43.389 1.000 89.853  0  202 ASP   A OD2 1 ? 
ATOM   1517 N  N   . GLN   B 1 93  ? -26.654 -4.317  -39.623 1.000 65.150  0  203 GLN   A N   1 ? 
ATOM   1518 C  CA  . GLN   B 1 93  ? -26.125 -5.567  -39.084 1.000 54.010  0  203 GLN   A CA  1 ? 
ATOM   1519 C  C   . GLN   B 1 93  ? -26.641 -5.806  -37.659 1.000 45.471  0  203 GLN   A C   1 ? 
ATOM   1520 O  O   . GLN   B 1 93  ? -26.286 -6.802  -37.037 1.000 45.215  0  203 GLN   A O   1 ? 
ATOM   1521 C  CB  . GLN   B 1 93  ? -24.597 -5.528  -39.094 1.000 52.229  0  203 GLN   A CB  1 ? 
ATOM   1522 C  CG  . GLN   B 1 93  ? -23.990 -5.438  -40.489 1.000 55.191  0  203 GLN   A CG  1 ? 
ATOM   1523 C  CD  . GLN   B 1 93  ? -24.276 -6.658  -41.336 1.000 56.497  0  203 GLN   A CD  1 ? 
ATOM   1524 O  OE1 . GLN   B 1 93  ? -25.034 -6.601  -42.309 1.000 67.445  0  203 GLN   A OE1 1 ? 
ATOM   1525 N  NE2 . GLN   B 1 93  ? -23.712 -7.789  -40.939 1.000 58.806  0  203 GLN   A NE2 1 ? 
ATOM   1526 N  N   . ALA   B 1 94  ? -27.522 -4.914  -37.176 1.000 43.863  0  204 ALA   A N   1 ? 
ATOM   1527 C  CA  . ALA   B 1 94  ? -28.040 -4.994  -35.814 1.000 41.904  0  204 ALA   A CA  1 ? 
ATOM   1528 C  C   . ALA   B 1 94  ? -28.900 -6.244  -35.642 1.000 45.062  0  204 ALA   A C   1 ? 
ATOM   1529 O  O   . ALA   B 1 94  ? -28.795 -6.935  -34.636 1.000 46.767  0  204 ALA   A O   1 ? 
ATOM   1530 C  CB  . ALA   B 1 94  ? -28.823 -3.741  -35.482 1.000 39.584  0  204 ALA   A CB  1 ? 
ATOM   1531 N  N   . GLU   B 1 95  ? -29.764 -6.507  -36.629 1.000 50.477  0  205 GLU   A N   1 ? 
ATOM   1532 C  CA  . GLU   B 1 95  ? -30.694 -7.623  -36.567 1.000 49.797  0  205 GLU   A CA  1 ? 
ATOM   1533 C  C   . GLU   B 1 95  ? -29.917 -8.948  -36.508 1.000 48.269  0  205 GLU   A C   1 ? 
ATOM   1534 O  O   . GLU   B 1 95  ? -30.138 -9.747  -35.601 1.000 51.972  0  205 GLU   A O   1 ? 
ATOM   1535 C  CB  . GLU   B 1 95  ? -31.678 -7.548  -37.738 1.000 57.260  0  205 GLU   A CB  1 ? 
ATOM   1536 C  CG  . GLU   B 1 95  ? -32.831 -8.544  -37.639 1.000 76.958  0  205 GLU   A CG  1 ? 
ATOM   1537 C  CD  . GLU   B 1 95  ? -33.774 -8.505  -38.830 1.000 90.261  0  205 GLU   A CD  1 ? 
ATOM   1538 O  OE1 . GLU   B 1 95  ? -34.371 -7.434  -39.074 1.000 100.200 0  205 GLU   A OE1 1 ? 
ATOM   1539 O  OE2 . GLU   B 1 95  ? -33.897 -9.536  -39.526 1.000 79.640  0  205 GLU   A OE2 1 ? 
ATOM   1540 N  N   . PRO   B 1 96  ? -28.989 -9.232  -37.465 1.000 44.718  0  206 PRO   A N   1 ? 
ATOM   1541 C  CA  . PRO   B 1 96  ? -28.227 -10.485 -37.435 1.000 41.446  0  206 PRO   A CA  1 ? 
ATOM   1542 C  C   . PRO   B 1 96  ? -27.344 -10.680 -36.196 1.000 40.102  0  206 PRO   A C   1 ? 
ATOM   1543 O  O   . PRO   B 1 96  ? -27.190 -11.802 -35.724 1.000 47.727  0  206 PRO   A O   1 ? 
ATOM   1544 C  CB  . PRO   B 1 96  ? -27.389 -10.443 -38.748 1.000 39.901  0  206 PRO   A CB  1 ? 
ATOM   1545 C  CG  . PRO   B 1 96  ? -27.430 -8.986  -39.182 1.000 42.060  0  206 PRO   A CG  1 ? 
ATOM   1546 C  CD  . PRO   B 1 96  ? -28.755 -8.461  -38.693 1.000 39.973  0  206 PRO   A CD  1 ? 
ATOM   1547 N  N   . VAL   B 1 97  ? -26.761 -9.584  -35.682 1.000 34.203  0  207 VAL   A N   1 ? 
ATOM   1548 C  CA  . VAL   B 1 97  ? -25.867 -9.660  -34.527 1.000 39.518  0  207 VAL   A CA  1 ? 
ATOM   1549 C  C   . VAL   B 1 97  ? -26.697 -9.899  -33.260 1.000 38.040  0  207 VAL   A C   1 ? 
ATOM   1550 O  O   . VAL   B 1 97  ? -26.291 -10.667 -32.392 1.000 33.161  0  207 VAL   A O   1 ? 
ATOM   1551 C  CB  . VAL   B 1 97  ? -24.970 -8.410  -34.385 1.000 40.804  0  207 VAL   A CB  1 ? 
ATOM   1552 C  CG1 . VAL   B 1 97  ? -24.256 -8.366  -33.037 1.000 40.102  0  207 VAL   A CG1 1 ? 
ATOM   1553 C  CG2 . VAL   B 1 97  ? -23.956 -8.313  -35.519 1.000 40.158  0  207 VAL   A CG2 1 ? 
ATOM   1554 N  N   . LEU   B 1 98  ? -27.853 -9.222  -33.159 1.000 43.678  0  208 LEU   A N   1 ? 
ATOM   1555 C  CA  . LEU   B 1 98  ? -28.737 -9.376  -32.008 1.000 43.133  0  208 LEU   A CA  1 ? 
ATOM   1556 C  C   . LEU   B 1 98  ? -29.269 -10.809 -31.962 1.000 45.418  0  208 LEU   A C   1 ? 
ATOM   1557 O  O   . LEU   B 1 98  ? -29.304 -11.424 -30.899 1.000 44.259  0  208 LEU   A O   1 ? 
ATOM   1558 C  CB  . LEU   B 1 98  ? -29.875 -8.356  -32.071 1.000 41.328  0  208 LEU   A CB  1 ? 
ATOM   1559 C  CG  . LEU   B 1 98  ? -30.888 -8.401  -30.919 1.000 45.454  0  208 LEU   A CG  1 ? 
ATOM   1560 C  CD1 . LEU   B 1 98  ? -30.213 -8.169  -29.572 1.000 46.002  0  208 LEU   A CD1 1 ? 
ATOM   1561 C  CD2 . LEU   B 1 98  ? -32.005 -7.387  -31.137 1.000 40.342  0  208 LEU   A CD2 1 ? 
ATOM   1562 N  N   . GLU   B 1 99  ? -29.651 -11.336 -33.139 1.000 46.399  0  209 GLU   A N   1 ? 
ATOM   1563 C  CA  . GLU   B 1 99  ? -30.161 -12.698 -33.269 1.000 51.360  0  209 GLU   A CA  1 ? 
ATOM   1564 C  C   . GLU   B 1 99  ? -29.175 -13.691 -32.643 1.000 41.287  0  209 GLU   A C   1 ? 
ATOM   1565 O  O   . GLU   B 1 99  ? -29.584 -14.606 -31.932 1.000 41.628  0  209 GLU   A O   1 ? 
ATOM   1566 C  CB  . GLU   B 1 99  ? -30.412 -13.014 -34.748 1.000 60.332  0  209 GLU   A CB  1 ? 
ATOM   1567 C  CG  . GLU   B 1 99  ? -30.816 -14.465 -35.022 1.000 67.083  0  209 GLU   A CG  1 ? 
ATOM   1568 C  CD  . GLU   B 1 99  ? -32.166 -14.887 -34.464 1.000 75.938  0  209 GLU   A CD  1 ? 
ATOM   1569 O  OE1 . GLU   B 1 99  ? -32.503 -16.083 -34.604 1.000 87.456  0  209 GLU   A OE1 1 ? 
ATOM   1570 O  OE2 . GLU   B 1 99  ? -32.897 -14.026 -33.929 1.000 84.573  0  209 GLU   A OE2 1 ? 
ATOM   1571 N  N   . VAL   B 1 100 ? -27.879 -13.505 -32.929 1.000 37.173  0  210 VAL   A N   1 ? 
ATOM   1572 C  CA  . VAL   B 1 100 ? -26.837 -14.381 -32.409 1.000 37.761  0  210 VAL   A CA  1 ? 
ATOM   1573 C  C   . VAL   B 1 100 ? -26.857 -14.346 -30.880 1.000 34.595  0  210 VAL   A C   1 ? 
ATOM   1574 O  O   . VAL   B 1 100 ? -26.832 -15.392 -30.237 1.000 35.552  0  210 VAL   A O   1 ? 
ATOM   1575 C  CB  . VAL   B 1 100 ? -25.449 -14.001 -32.961 1.000 40.115  0  210 VAL   A CB  1 ? 
ATOM   1576 C  CG1 . VAL   B 1 100 ? -24.315 -14.644 -32.160 1.000 36.672  0  210 VAL   A CG1 1 ? 
ATOM   1577 C  CG2 . VAL   B 1 100 ? -25.323 -14.344 -34.442 1.000 40.290  0  210 VAL   A CG2 1 ? 
ATOM   1578 N  N   . TYR   B 1 101 ? -26.912 -13.134 -30.312 1.000 34.127  0  211 TYR   A N   1 ? 
ATOM   1579 C  CA  . TYR   B 1 101 ? -26.850 -12.956 -28.866 1.000 36.687  0  211 TYR   A CA  1 ? 
ATOM   1580 C  C   . TYR   B 1 101 ? -28.118 -13.511 -28.215 1.000 36.464  0  211 TYR   A C   1 ? 
ATOM   1581 O  O   . TYR   B 1 101 ? -28.050 -14.093 -27.135 1.000 32.799  0  211 TYR   A O   1 ? 
ATOM   1582 C  CB  . TYR   B 1 101 ? -26.619 -11.480 -28.522 1.000 33.974  0  211 TYR   A CB  1 ? 
ATOM   1583 C  CG  . TYR   B 1 101 ? -25.168 -11.030 -28.613 1.000 33.798  0  211 TYR   A CG  1 ? 
ATOM   1584 C  CD1 . TYR   B 1 101 ? -24.144 -11.784 -28.045 1.000 35.811  0  211 TYR   A CD1 1 ? 
ATOM   1585 C  CD2 . TYR   B 1 101 ? -24.814 -9.882  -29.311 1.000 36.117  0  211 TYR   A CD2 1 ? 
ATOM   1586 C  CE1 . TYR   B 1 101 ? -22.820 -11.387 -28.132 1.000 32.330  0  211 TYR   A CE1 1 ? 
ATOM   1587 C  CE2 . TYR   B 1 101 ? -23.492 -9.477  -29.415 1.000 33.553  0  211 TYR   A CE2 1 ? 
ATOM   1588 C  CZ  . TYR   B 1 101 ? -22.492 -10.229 -28.819 1.000 38.814  0  211 TYR   A CZ  1 ? 
ATOM   1589 O  OH  . TYR   B 1 101 ? -21.188 -9.830  -28.910 1.000 34.170  0  211 TYR   A OH  1 ? 
ATOM   1590 N  N   . GLN   B 1 102 ? -29.269 -13.312 -28.875 1.000 40.684  0  212 GLN   A N   1 ? 
ATOM   1591 C  CA  . GLN   B 1 102 ? -30.545 -13.796 -28.364 1.000 40.777  0  212 GLN   A CA  1 ? 
ATOM   1592 C  C   . GLN   B 1 102 ? -30.546 -15.323 -28.322 1.000 37.833  0  212 GLN   A C   1 ? 
ATOM   1593 O  O   . GLN   B 1 102 ? -30.989 -15.912 -27.339 1.000 39.664  0  212 GLN   A O   1 ? 
ATOM   1594 C  CB  . GLN   B 1 102 ? -31.715 -13.297 -29.211 1.000 44.825  0  212 GLN   A CB  1 ? 
ATOM   1595 C  CG  . GLN   B 1 102 ? -31.960 -11.796 -29.111 1.000 45.284  0  212 GLN   A CG  1 ? 
ATOM   1596 C  CD  . GLN   B 1 102 ? -33.109 -11.326 -29.977 1.000 43.299  0  212 GLN   A CD  1 ? 
ATOM   1597 O  OE1 . GLN   B 1 102 ? -33.232 -11.710 -31.146 1.000 44.663  0  212 GLN   A OE1 1 ? 
ATOM   1598 N  NE2 . GLN   B 1 102 ? -33.985 -10.516 -29.401 1.000 45.681  0  212 GLN   A NE2 1 ? 
ATOM   1599 N  N   . ARG   B 1 103 ? -30.030 -15.957 -29.388 1.000 32.652  0  213 ARG   A N   1 ? 
ATOM   1600 C  CA  . ARG   B 1 103 ? -30.091 -17.407 -29.509 1.000 39.290  0  213 ARG   A CA  1 ? 
ATOM   1601 C  C   . ARG   B 1 103 ? -29.023 -18.066 -28.627 1.000 37.140  0  213 ARG   A C   1 ? 
ATOM   1602 O  O   . ARG   B 1 103 ? -29.225 -19.182 -28.157 1.000 41.212  0  213 ARG   A O   1 ? 
ATOM   1603 C  CB  . ARG   B 1 103 ? -30.049 -17.860 -30.975 1.000 40.244  0  213 ARG   A CB  1 ? 
ATOM   1604 C  CG  . ARG   B 1 103 ? -31.383 -17.644 -31.687 1.000 45.603  0  213 ARG   A CG  1 ? 
ATOM   1605 C  CD  . ARG   B 1 103 ? -31.629 -18.621 -32.835 1.000 62.463  0  213 ARG   A CD  1 ? 
ATOM   1606 N  NE  . ARG   B 1 103 ? -30.945 -18.254 -34.081 1.000 69.922  0  213 ARG   A NE  1 ? 
ATOM   1607 C  CZ  . ARG   B 1 103 ? -30.992 -18.965 -35.212 1.000 67.035  0  213 ARG   A CZ  1 ? 
ATOM   1608 N  NH1 . ARG   B 1 103 ? -31.591 -20.148 -35.235 1.000 57.875  0  213 ARG   A NH1 1 ? 
ATOM   1609 N  NH2 . ARG   B 1 103 ? -30.384 -18.514 -36.302 1.000 66.017  0  213 ARG   A NH2 1 ? 
ATOM   1610 N  N   . LEU   B 1 104 ? -27.897 -17.370 -28.396 1.000 34.486  0  214 LEU   A N   1 ? 
ATOM   1611 C  CA  . LEU   B 1 104 ? -26.907 -17.828 -27.422 1.000 34.413  0  214 LEU   A CA  1 ? 
ATOM   1612 C  C   . LEU   B 1 104 ? -27.516 -17.752 -26.022 1.000 33.520  0  214 LEU   A C   1 ? 
ATOM   1613 O  O   . LEU   B 1 104 ? -27.319 -18.651 -25.207 1.000 34.411  0  214 LEU   A O   1 ? 
ATOM   1614 C  CB  . LEU   B 1 104 ? -25.614 -17.011 -27.500 1.000 32.938  0  214 LEU   A CB  1 ? 
ATOM   1615 C  CG  . LEU   B 1 104 ? -24.704 -17.283 -28.701 1.000 33.262  0  214 LEU   A CG  1 ? 
ATOM   1616 C  CD1 . LEU   B 1 104 ? -23.547 -16.309 -28.701 1.000 35.794  0  214 LEU   A CD1 1 ? 
ATOM   1617 C  CD2 . LEU   B 1 104 ? -24.190 -18.717 -28.718 1.000 35.500  0  214 LEU   A CD2 1 ? 
ATOM   1618 N  N   . HIS   B 1 105 ? -28.283 -16.678 -25.772 1.000 30.839  0  215 HIS   A N   1 ? 
ATOM   1619 C  CA  . HIS   B 1 105 ? -28.874 -16.426 -24.465 1.000 33.021  0  215 HIS   A CA  1 ? 
ATOM   1620 C  C   . HIS   B 1 105 ? -29.904 -17.511 -24.128 1.000 33.767  0  215 HIS   A C   1 ? 
ATOM   1621 O  O   . HIS   B 1 105 ? -29.970 -17.967 -22.990 1.000 35.703  0  215 HIS   A O   1 ? 
ATOM   1622 C  CB  . HIS   B 1 105 ? -29.493 -15.023 -24.419 1.000 34.188  0  215 HIS   A CB  1 ? 
ATOM   1623 C  CG  . HIS   B 1 105 ? -29.863 -14.562 -23.049 1.000 42.646  0  215 HIS   A CG  1 ? 
ATOM   1624 N  ND1 . HIS   B 1 105 ? -31.062 -14.877 -22.445 1.000 46.353  0  215 HIS   A ND1 1 ? 
ATOM   1625 C  CD2 . HIS   B 1 105 ? -29.190 -13.810 -22.162 1.000 43.694  0  215 HIS   A CD2 1 ? 
ATOM   1626 C  CE1 . HIS   B 1 105 ? -31.101 -14.331 -21.238 1.000 40.963  0  215 HIS   A CE1 1 ? 
ATOM   1627 N  NE2 . HIS   B 1 105 ? -29.979 -13.672 -21.049 1.000 39.113  0  215 HIS   A NE2 1 ? 
ATOM   1628 N  N   . SER   B 1 106 ? -30.684 -17.935 -25.140 1.000 32.488  0  216 SER   A N   1 ? 
ATOM   1629 C  CA  . SER   B 1 106 ? -31.785 -18.871 -24.930 1.000 37.017  0  216 SER   A CA  1 ? 
ATOM   1630 C  C   . SER   B 1 106 ? -31.396 -20.287 -25.372 1.000 42.613  0  216 SER   A C   1 ? 
ATOM   1631 O  O   . SER   B 1 106 ? -32.260 -21.155 -25.485 1.000 45.017  0  216 SER   A O   1 ? 
ATOM   1632 C  CB  . SER   B 1 106 ? -33.032 -18.403 -25.653 1.000 34.424  0  216 SER   A CB  1 ? 
ATOM   1633 O  OG  . SER   B 1 106 ? -32.832 -18.382 -27.061 1.000 34.287  0  216 SER   A OG  1 ? 
ATOM   1634 N  N   . ASP   B 1 107 ? -30.090 -20.520 -25.584 1.000 44.851  0  217 ASP   A N   1 ? 
ATOM   1635 C  CA  . ASP   B 1 107 ? -29.607 -21.804 -26.077 1.000 42.690  0  217 ASP   A CA  1 ? 
ATOM   1636 C  C   . ASP   B 1 107 ? -29.736 -22.849 -24.971 1.000 45.577  0  217 ASP   A C   1 ? 
ATOM   1637 O  O   . ASP   B 1 107 ? -29.538 -22.542 -23.798 1.000 49.711  0  217 ASP   A O   1 ? 
ATOM   1638 C  CB  . ASP   B 1 107 ? -28.162 -21.709 -26.551 1.000 42.600  0  217 ASP   A CB  1 ? 
ATOM   1639 C  CG  . ASP   B 1 107 ? -27.684 -22.842 -27.453 1.000 43.692  0  217 ASP   A CG  1 ? 
ATOM   1640 O  OD1 . ASP   B 1 107 ? -28.536 -23.663 -27.881 1.000 40.960  0  217 ASP   A OD1 1 ? 
ATOM   1641 O  OD2 . ASP   B 1 107 ? -26.464 -22.890 -27.733 1.000 36.292  0  217 ASP   A OD2 1 ? 
ATOM   1642 N  N   . LYS   B 1 108 ? -30.068 -24.085 -25.368 1.000 51.631  0  218 LYS   A N   1 ? 
ATOM   1643 C  CA  . LYS   B 1 108 ? -30.123 -25.211 -24.446 1.000 52.713  0  218 LYS   A CA  1 ? 
ATOM   1644 C  C   . LYS   B 1 108 ? -29.412 -26.406 -25.076 1.000 48.121  0  218 LYS   A C   1 ? 
ATOM   1645 O  O   . LYS   B 1 108 ? -29.706 -26.780 -26.209 1.000 54.666  0  218 LYS   A O   1 ? 
ATOM   1646 C  CB  . LYS   B 1 108 ? -31.570 -25.573 -24.087 1.000 57.346  0  218 LYS   A CB  1 ? 
ATOM   1647 C  CG  . LYS   B 1 108 ? -32.331 -24.504 -23.310 1.000 64.978  0  218 LYS   A CG  1 ? 
ATOM   1648 C  CD  . LYS   B 1 108 ? -33.612 -24.998 -22.645 1.000 81.989  0  218 LYS   A CD  1 ? 
ATOM   1649 C  CE  . LYS   B 1 108 ? -33.351 -25.955 -21.511 1.000 88.750  0  218 LYS   A CE  1 ? 
ATOM   1650 N  NZ  . LYS   B 1 108 ? -34.589 -26.348 -20.831 1.000 95.281  0  218 LYS   A NZ  1 ? 
ATOM   1651 N  N   . GLY   B 1 109 ? -28.450 -26.974 -24.334 1.000 39.864  0  219 GLY   A N   1 ? 
ATOM   1652 C  CA  . GLY   B 1 109 ? -27.704 -28.139 -24.787 1.000 39.216  0  219 GLY   A CA  1 ? 
ATOM   1653 C  C   . GLY   B 1 109 ? -26.633 -27.770 -25.820 1.000 46.132  0  219 GLY   A C   1 ? 
ATOM   1654 O  O   . GLY   B 1 109 ? -26.051 -28.650 -26.448 1.000 48.669  0  219 GLY   A O   1 ? 
ATOM   1655 N  N   . GLY   B 1 110 ? -26.366 -26.460 -25.970 1.000 39.382  0  220 GLY   A N   1 ? 
ATOM   1656 C  CA  . GLY   B 1 110 ? -25.367 -25.975 -26.911 1.000 38.340  0  220 GLY   A CA  1 ? 
ATOM   1657 C  C   . GLY   B 1 110 ? -25.759 -26.268 -28.362 1.000 40.928  0  220 GLY   A C   1 ? 
ATOM   1658 O  O   . GLY   B 1 110 ? -24.892 -26.434 -29.217 1.000 49.604  0  220 GLY   A O   1 ? 
ATOM   1659 N  N   . SER   B 1 111 ? -27.072 -26.260 -28.634 1.000 39.140  0  221 SER   A N   1 ? 
ATOM   1660 C  CA  . SER   B 1 111 ? -27.601 -26.602 -29.947 1.000 37.664  0  221 SER   A CA  1 ? 
ATOM   1661 C  C   . SER   B 1 111 ? -27.234 -25.518 -30.967 1.000 36.657  0  221 SER   A C   1 ? 
ATOM   1662 O  O   . SER   B 1 111 ? -26.674 -25.816 -32.018 1.000 44.227  0  221 SER   A O   1 ? 
ATOM   1663 C  CB  . SER   B 1 111 ? -29.097 -26.815 -29.881 1.000 44.195  0  221 SER   A CB  1 ? 
ATOM   1664 O  OG  . SER   B 1 111 ? -29.639 -27.095 -31.163 1.000 54.721  0  221 SER   A OG  1 ? 
ATOM   1665 N  N   . PHE   B 1 112 ? -27.569 -24.263 -30.645 1.000 34.062  0  222 PHE   A N   1 ? 
ATOM   1666 C  CA  . PHE   B 1 112 ? -27.289 -23.133 -31.526 1.000 35.698  0  222 PHE   A CA  1 ? 
ATOM   1667 C  C   . PHE   B 1 112 ? -25.783 -22.857 -31.557 1.000 38.217  0  222 PHE   A C   1 ? 
ATOM   1668 O  O   . PHE   B 1 112 ? -25.236 -22.504 -32.600 1.000 40.052  0  222 PHE   A O   1 ? 
ATOM   1669 C  CB  . PHE   B 1 112 ? -28.067 -21.898 -31.073 1.000 32.976  0  222 PHE   A CB  1 ? 
ATOM   1670 C  CG  . PHE   B 1 112 ? -27.723 -20.636 -31.847 1.000 40.458  0  222 PHE   A CG  1 ? 
ATOM   1671 C  CD1 . PHE   B 1 112 ? -28.255 -20.407 -33.115 1.000 46.035  0  222 PHE   A CD1 1 ? 
ATOM   1672 C  CD2 . PHE   B 1 112 ? -26.872 -19.675 -31.303 1.000 39.358  0  222 PHE   A CD2 1 ? 
ATOM   1673 C  CE1 . PHE   B 1 112 ? -27.926 -19.256 -33.822 1.000 45.899  0  222 PHE   A CE1 1 ? 
ATOM   1674 C  CE2 . PHE   B 1 112 ? -26.552 -18.528 -32.014 1.000 39.174  0  222 PHE   A CE2 1 ? 
ATOM   1675 C  CZ  . PHE   B 1 112 ? -27.080 -18.320 -33.269 1.000 42.560  0  222 PHE   A CZ  1 ? 
ATOM   1676 N  N   . GLU   B 1 113 ? -25.138 -22.970 -30.390 1.000 33.868  0  223 GLU   A N   1 ? 
ATOM   1677 C  CA  . GLU   B 1 113 ? -23.701 -22.783 -30.270 1.000 38.377  0  223 GLU   A CA  1 ? 
ATOM   1678 C  C   . GLU   B 1 113 ? -22.976 -23.673 -31.286 1.000 41.396  0  223 GLU   A C   1 ? 
ATOM   1679 O  O   . GLU   B 1 113 ? -22.053 -23.221 -31.959 1.000 39.858  0  223 GLU   A O   1 ? 
ATOM   1680 C  CB  . GLU   B 1 113 ? -23.282 -23.088 -28.830 1.000 40.542  0  223 GLU   A CB  1 ? 
ATOM   1681 C  CG  . GLU   B 1 113 ? -21.773 -23.155 -28.620 1.000 42.213  0  223 GLU   A CG  1 ? 
ATOM   1682 C  CD  . GLU   B 1 113 ? -21.362 -23.436 -27.183 1.000 49.190  0  223 GLU   A CD  1 ? 
ATOM   1683 O  OE1 . GLU   B 1 113 ? -22.213 -23.295 -26.271 1.000 50.902  0  223 GLU   A OE1 1 ? 
ATOM   1684 O  OE2 . GLU   B 1 113 ? -20.215 -23.884 -26.987 1.000 46.005  0  223 GLU   A OE2 1 ? 
ATOM   1685 N  N   . ALA   B 1 114 ? -23.418 -24.936 -31.388 1.000 40.312  0  224 ALA   A N   1 ? 
ATOM   1686 C  CA  . ALA   B 1 114 ? -22.789 -25.915 -32.265 1.000 43.501  0  224 ALA   A CA  1 ? 
ATOM   1687 C  C   . ALA   B 1 114 ? -23.036 -25.556 -33.732 1.000 42.706  0  224 ALA   A C   1 ? 
ATOM   1688 O  O   . ALA   B 1 114 ? -22.181 -25.795 -34.579 1.000 43.025  0  224 ALA   A O   1 ? 
ATOM   1689 C  CB  . ALA   B 1 114 ? -23.306 -27.302 -31.942 1.000 43.714  0  224 ALA   A CB  1 ? 
ATOM   1690 N  N   . ALA   B 1 115 ? -24.224 -25.004 -34.020 1.000 45.309  0  225 ALA   A N   1 ? 
ATOM   1691 C  CA  . ALA   B 1 115 ? -24.593 -24.622 -35.379 1.000 48.450  0  225 ALA   A CA  1 ? 
ATOM   1692 C  C   . ALA   B 1 115 ? -23.731 -23.444 -35.853 1.000 44.125  0  225 ALA   A C   1 ? 
ATOM   1693 O  O   . ALA   B 1 115 ? -23.371 -23.371 -37.026 1.000 39.168  0  225 ALA   A O   1 ? 
ATOM   1694 C  CB  . ALA   B 1 115 ? -26.072 -24.293 -35.443 1.000 43.505  0  225 ALA   A CB  1 ? 
ATOM   1695 N  N   . LEU   B 1 116 ? -23.435 -22.510 -34.932 1.000 45.758  0  226 LEU   A N   1 ? 
ATOM   1696 C  CA  . LEU   B 1 116 ? -22.549 -21.387 -35.224 1.000 43.931  0  226 LEU   A CA  1 ? 
ATOM   1697 C  C   . LEU   B 1 116 ? -21.206 -21.910 -35.717 1.000 38.191  0  226 LEU   A C   1 ? 
ATOM   1698 O  O   . LEU   B 1 116 ? -20.698 -21.446 -36.731 1.000 42.503  0  226 LEU   A O   1 ? 
ATOM   1699 C  CB  . LEU   B 1 116 ? -22.360 -20.481 -34.004 1.000 48.538  0  226 LEU   A CB  1 ? 
ATOM   1700 C  CG  . LEU   B 1 116 ? -23.198 -19.203 -33.967 1.000 42.441  0  226 LEU   A CG  1 ? 
ATOM   1701 C  CD1 . LEU   B 1 116 ? -22.971 -18.468 -32.660 1.000 46.127  0  226 LEU   A CD1 1 ? 
ATOM   1702 C  CD2 . LEU   B 1 116 ? -22.872 -18.303 -35.138 1.000 42.919  0  226 LEU   A CD2 1 ? 
ATOM   1703 N  N   . TRP   B 1 117 ? -20.619 -22.842 -34.955 1.000 32.050  0  227 TRP   A N   1 ? 
ATOM   1704 C  CA  . TRP   B 1 117 ? -19.315 -23.395 -35.284 1.000 39.256  0  227 TRP   A CA  1 ? 
ATOM   1705 C  C   . TRP   B 1 117 ? -19.315 -23.930 -36.717 1.000 39.697  0  227 TRP   A C   1 ? 
ATOM   1706 O  O   . TRP   B 1 117 ? -18.434 -23.600 -37.501 1.000 42.302  0  227 TRP   A O   1 ? 
ATOM   1707 C  CB  . TRP   B 1 117 ? -18.932 -24.491 -34.280 1.000 38.521  0  227 TRP   A CB  1 ? 
ATOM   1708 C  CG  . TRP   B 1 117 ? -17.615 -25.155 -34.581 1.000 37.127  0  227 TRP   A CG  1 ? 
ATOM   1709 C  CD1 . TRP   B 1 117 ? -17.421 -26.323 -35.259 1.000 34.729  0  227 TRP   A CD1 1 ? 
ATOM   1710 C  CD2 . TRP   B 1 117 ? -16.302 -24.658 -34.251 1.000 37.861  0  227 TRP   A CD2 1 ? 
ATOM   1711 N  NE1 . TRP   B 1 117 ? -16.083 -26.607 -35.343 1.000 38.258  0  227 TRP   A NE1 1 ? 
ATOM   1712 C  CE2 . TRP   B 1 117 ? -15.371 -25.601 -34.740 1.000 39.325  0  227 TRP   A CE2 1 ? 
ATOM   1713 C  CE3 . TRP   B 1 117 ? -15.826 -23.526 -33.580 1.000 35.866  0  227 TRP   A CE3 1 ? 
ATOM   1714 C  CZ2 . TRP   B 1 117 ? -13.996 -25.437 -34.585 1.000 36.746  0  227 TRP   A CZ2 1 ? 
ATOM   1715 C  CZ3 . TRP   B 1 117 ? -14.466 -23.372 -33.418 1.000 37.297  0  227 TRP   A CZ3 1 ? 
ATOM   1716 C  CH2 . TRP   B 1 117 ? -13.565 -24.312 -33.921 1.000 39.398  0  227 TRP   A CH2 1 ? 
ATOM   1717 N  N   . GLN   B 1 118 ? -20.335 -24.738 -37.041 1.000 49.654  0  228 GLN   A N   1 ? 
ATOM   1718 C  CA  . GLN   B 1 118 ? -20.474 -25.362 -38.354 1.000 54.406  0  228 GLN   A CA  1 ? 
ATOM   1719 C  C   . GLN   B 1 118 ? -20.634 -24.296 -39.442 1.000 51.638  0  228 GLN   A C   1 ? 
ATOM   1720 O  O   . GLN   B 1 118 ? -19.922 -24.314 -40.442 1.000 51.472  0  228 GLN   A O   1 ? 
ATOM   1721 C  CB  . GLN   B 1 118 ? -21.704 -26.270 -38.335 1.000 58.899  0  228 GLN   A CB  1 ? 
ATOM   1722 C  CG  . GLN   B 1 118 ? -22.083 -26.849 -39.693 1.000 65.466  0  228 GLN   A CG  1 ? 
ATOM   1723 C  CD  . GLN   B 1 118 ? -23.569 -27.111 -39.817 1.000 72.862  0  228 GLN   A CD  1 ? 
ATOM   1724 O  OE1 . GLN   B 1 118 ? -24.181 -27.755 -38.958 1.000 73.968  0  228 GLN   A OE1 1 ? 
ATOM   1725 N  NE2 . GLN   B 1 118 ? -24.182 -26.530 -40.839 1.000 80.129  0  228 GLN   A NE2 1 ? 
ATOM   1726 N  N   . GLN   B 1 119 ? -21.609 -23.398 -39.241 1.000 54.804  0  229 GLN   A N   1 ? 
ATOM   1727 C  CA  . GLN   B 1 119 ? -22.029 -22.442 -40.260 1.000 52.467  0  229 GLN   A CA  1 ? 
ATOM   1728 C  C   . GLN   B 1 119 ? -20.914 -21.432 -40.550 1.000 45.709  0  229 GLN   A C   1 ? 
ATOM   1729 O  O   . GLN   B 1 119 ? -20.615 -21.159 -41.709 1.000 48.543  0  229 GLN   A O   1 ? 
ATOM   1730 C  CB  . GLN   B 1 119 ? -23.301 -21.730 -39.789 1.000 63.823  0  229 GLN   A CB  1 ? 
ATOM   1731 C  CG  . GLN   B 1 119 ? -23.841 -20.683 -40.761 1.000 74.255  0  229 GLN   A CG  1 ? 
ATOM   1732 C  CD  . GLN   B 1 119 ? -24.416 -21.283 -42.027 1.000 89.765  0  229 GLN   A CD  1 ? 
ATOM   1733 O  OE1 . GLN   B 1 119 ? -25.372 -22.065 -41.991 1.000 100.032 0  229 GLN   A OE1 1 ? 
ATOM   1734 N  NE2 . GLN   B 1 119 ? -23.853 -20.903 -43.167 1.000 93.474  0  229 GLN   A NE2 1 ? 
ATOM   1735 N  N   . TRP   B 1 120 ? -20.329 -20.865 -39.487 1.000 45.247  0  230 TRP   A N   1 ? 
ATOM   1736 C  CA  . TRP   B 1 120 ? -19.411 -19.735 -39.615 1.000 48.280  0  230 TRP   A CA  1 ? 
ATOM   1737 C  C   . TRP   B 1 120 ? -17.998 -20.206 -39.953 1.000 51.290  0  230 TRP   A C   1 ? 
ATOM   1738 O  O   . TRP   B 1 120 ? -17.604 -21.318 -39.606 1.000 57.487  0  230 TRP   A O   1 ? 
ATOM   1739 C  CB  . TRP   B 1 120 ? -19.408 -18.901 -38.327 1.000 46.544  0  230 TRP   A CB  1 ? 
ATOM   1740 C  CG  . TRP   B 1 120 ? -20.586 -17.976 -38.187 1.000 47.279  0  230 TRP   A CG  1 ? 
ATOM   1741 C  CD1 . TRP   B 1 120 ? -21.770 -18.030 -38.863 1.000 52.441  0  230 TRP   A CD1 1 ? 
ATOM   1742 C  CD2 . TRP   B 1 120 ? -20.698 -16.869 -37.270 1.000 47.397  0  230 TRP   A CD2 1 ? 
ATOM   1743 N  NE1 . TRP   B 1 120 ? -22.598 -17.017 -38.455 1.000 56.032  0  230 TRP   A NE1 1 ? 
ATOM   1744 C  CE2 . TRP   B 1 120 ? -21.972 -16.294 -37.473 1.000 47.956  0  230 TRP   A CE2 1 ? 
ATOM   1745 C  CE3 . TRP   B 1 120 ? -19.852 -16.312 -36.302 1.000 47.610  0  230 TRP   A CE3 1 ? 
ATOM   1746 C  CZ2 . TRP   B 1 120 ? -22.411 -15.190 -36.747 1.000 47.174  0  230 TRP   A CZ2 1 ? 
ATOM   1747 C  CZ3 . TRP   B 1 120 ? -20.290 -15.222 -35.583 1.000 46.233  0  230 TRP   A CZ3 1 ? 
ATOM   1748 C  CH2 . TRP   B 1 120 ? -21.551 -14.668 -35.807 1.000 50.441  0  230 TRP   A CH2 1 ? 
ATOM   1749 N  N   . ASP   B 1 121 ? -17.241 -19.315 -40.618 1.000 50.316  0  231 ASP   A N   1 ? 
ATOM   1750 C  CA  . ASP   B 1 121 ? -15.816 -19.510 -40.872 1.000 59.564  0  231 ASP   A CA  1 ? 
ATOM   1751 C  C   . ASP   B 1 121 ? -15.023 -19.031 -39.652 1.000 53.457  0  231 ASP   A C   1 ? 
ATOM   1752 O  O   . ASP   B 1 121 ? -15.562 -18.329 -38.798 1.000 51.981  0  231 ASP   A O   1 ? 
ATOM   1753 C  CB  . ASP   B 1 121 ? -15.385 -18.784 -42.139 1.000 62.950  0  231 ASP   A CB  1 ? 
ATOM   1754 C  CG  . ASP   B 1 121 ? -15.753 -17.306 -42.199 1.000 69.679  0  231 ASP   A CG  1 ? 
ATOM   1755 O  OD1 . ASP   B 1 121 ? -16.965 -17.003 -42.142 1.000 97.538  0  231 ASP   A OD1 1 ? 
ATOM   1756 O  OD2 . ASP   B 1 121 ? -14.830 -16.472 -42.275 1.000 71.868  0  231 ASP   A OD2 1 ? 
ATOM   1757 N  N   . ARG   B 1 122 ? -13.723 -19.365 -39.620 1.000 60.037  0  232 ARG   A N   1 ? 
ATOM   1758 C  CA  . ARG   B 1 122 ? -12.869 -19.057 -38.477 1.000 62.281  0  232 ARG   A CA  1 ? 
ATOM   1759 C  C   . ARG   B 1 122 ? -12.848 -17.551 -38.215 1.000 56.678  0  232 ARG   A C   1 ? 
ATOM   1760 O  O   . ARG   B 1 122 ? -13.083 -17.117 -37.093 1.000 53.774  0  232 ARG   A O   1 ? 
ATOM   1761 C  CB  . ARG   B 1 122 ? -11.430 -19.554 -38.674 1.000 60.352  0  232 ARG   A CB  1 ? 
ATOM   1762 C  CG  . ARG   B 1 122 ? -11.262 -21.066 -38.660 1.000 66.700  0  232 ARG   A CG  1 ? 
ATOM   1763 C  CD  . ARG   B 1 122 ? -9.791  -21.487 -38.501 1.000 75.526  0  232 ARG   A CD  1 ? 
ATOM   1764 N  NE  . ARG   B 1 122 ? -9.305  -21.395 -37.112 1.000 70.950  0  232 ARG   A NE  1 ? 
ATOM   1765 C  CZ  . ARG   B 1 122 ? -8.293  -20.632 -36.673 1.000 58.727  0  232 ARG   A CZ  1 ? 
ATOM   1766 N  NH1 . ARG   B 1 122 ? -7.708  -19.762 -37.477 1.000 58.349  0  232 ARG   A NH1 1 ? 
ATOM   1767 N  NH2 . ARG   B 1 122 ? -7.908  -20.707 -35.407 1.000 62.399  0  232 ARG   A NH2 1 ? 
ATOM   1768 N  N   . GLN   B 1 123 ? -12.564 -16.765 -39.263 1.000 55.082  0  233 GLN   A N   1 ? 
ATOM   1769 C  CA  . GLN   B 1 123 ? -12.316 -15.334 -39.109 1.000 59.972  0  233 GLN   A CA  1 ? 
ATOM   1770 C  C   . GLN   B 1 123 ? -13.576 -14.620 -38.608 1.000 48.609  0  233 GLN   A C   1 ? 
ATOM   1771 O  O   . GLN   B 1 123 ? -13.486 -13.728 -37.766 1.000 47.923  0  233 GLN   A O   1 ? 
ATOM   1772 C  CB  . GLN   B 1 123 ? -11.792 -14.730 -40.413 1.000 61.162  0  233 GLN   A CB  1 ? 
ATOM   1773 C  CG  . GLN   B 1 123 ? -10.402 -15.223 -40.810 1.000 76.585  0  233 GLN   A CG  1 ? 
ATOM   1774 C  CD  . GLN   B 1 123 ? -9.344  -14.945 -39.757 1.000 79.825  0  233 GLN   A CD  1 ? 
ATOM   1775 O  OE1 . GLN   B 1 123 ? -9.161  -13.807 -39.311 1.000 78.719  0  233 GLN   A OE1 1 ? 
ATOM   1776 N  NE2 . GLN   B 1 123 ? -8.649  -15.993 -39.330 1.000 80.299  0  233 GLN   A NE2 1 ? 
ATOM   1777 N  N   . SER   B 1 124 ? -14.742 -15.000 -39.151 1.000 44.071  0  234 SER   A N   1 ? 
ATOM   1778 C  CA  . SER   B 1 124 ? -16.018 -14.457 -38.693 1.000 44.745  0  234 SER   A CA  1 ? 
ATOM   1779 C  C   . SER   B 1 124 ? -16.234 -14.803 -37.217 1.000 43.532  0  234 SER   A C   1 ? 
ATOM   1780 O  O   . SER   B 1 124 ? -16.800 -14.016 -36.467 1.000 49.251  0  234 SER   A O   1 ? 
ATOM   1781 C  CB  . SER   B 1 124 ? -17.168 -14.960 -39.542 1.000 42.897  0  234 SER   A CB  1 ? 
ATOM   1782 O  OG  . SER   B 1 124 ? -17.067 -14.487 -40.875 1.000 46.707  0  234 SER   A OG  1 ? 
ATOM   1783 N  N   . LEU   B 1 125 ? -15.768 -15.993 -36.823 1.000 42.549  0  235 LEU   A N   1 ? 
ATOM   1784 C  CA  . LEU   B 1 125 ? -15.950 -16.498 -35.473 1.000 43.859  0  235 LEU   A CA  1 ? 
ATOM   1785 C  C   . LEU   B 1 125 ? -14.914 -15.864 -34.534 1.000 38.490  0  235 LEU   A C   1 ? 
ATOM   1786 O  O   . LEU   B 1 125 ? -15.234 -15.517 -33.403 1.000 40.310  0  235 LEU   A O   1 ? 
ATOM   1787 C  CB  . LEU   B 1 125 ? -15.844 -18.026 -35.533 1.000 46.769  0  235 LEU   A CB  1 ? 
ATOM   1788 C  CG  . LEU   B 1 125 ? -16.279 -18.798 -34.284 1.000 58.245  0  235 LEU   A CG  1 ? 
ATOM   1789 C  CD1 . LEU   B 1 125 ? -16.871 -20.141 -34.670 1.000 67.617  0  235 LEU   A CD1 1 ? 
ATOM   1790 C  CD2 . LEU   B 1 125 ? -15.120 -19.001 -33.335 1.000 68.770  0  235 LEU   A CD2 1 ? 
ATOM   1791 N  N   . ILE   B 1 126 ? -13.689 -15.663 -35.041 1.000 38.233  0  236 ILE   A N   1 ? 
ATOM   1792 C  CA  . ILE   B 1 126 ? -12.612 -15.069 -34.256 1.000 41.193  0  236 ILE   A CA  1 ? 
ATOM   1793 C  C   . ILE   B 1 126 ? -12.926 -13.593 -33.984 1.000 41.840  0  236 ILE   A C   1 ? 
ATOM   1794 O  O   . ILE   B 1 126 ? -12.723 -13.111 -32.870 1.000 43.764  0  236 ILE   A O   1 ? 
ATOM   1795 C  CB  . ILE   B 1 126 ? -11.249 -15.257 -34.958 1.000 44.152  0  236 ILE   A CB  1 ? 
ATOM   1796 C  CG1 . ILE   B 1 126 ? -10.758 -16.716 -34.829 1.000 44.363  0  236 ILE   A CG1 1 ? 
ATOM   1797 C  CG2 . ILE   B 1 126 ? -10.211 -14.259 -34.428 1.000 47.963  0  236 ILE   A CG2 1 ? 
ATOM   1798 C  CD1 . ILE   B 1 126 ? -9.367  -16.968 -35.388 1.000 46.799  0  236 ILE   A CD1 1 ? 
ATOM   1799 N  N   . MET   B 1 127 ? -13.403 -12.882 -35.011 1.000 39.711  0  237 MET   A N   1 ? 
ATOM   1800 C  CA  . MET   B 1 127 ? -13.737 -11.469 -34.875 1.000 46.565  0  237 MET   A CA  1 ? 
ATOM   1801 C  C   . MET   B 1 127 ? -14.871 -11.290 -33.859 1.000 42.411  0  237 MET   A C   1 ? 
ATOM   1802 O  O   . MET   B 1 127 ? -14.852 -10.347 -33.071 1.000 39.871  0  237 MET   A O   1 ? 
ATOM   1803 C  CB  . MET   B 1 127 ? -14.144 -10.861 -36.223 1.000 51.283  0  237 MET   A CB  1 ? 
ATOM   1804 C  CG  . MET   B 1 127 ? -12.971 -10.580 -37.148 1.000 60.847  0  237 MET   A CG  1 ? 
ATOM   1805 S  SD  . MET   B 1 127 ? -13.453 -9.708  -38.653 1.000 73.371  0  237 MET   A SD  1 ? 
ATOM   1806 C  CE  . MET   B 1 127 ? -14.488 -10.928 -39.475 1.000 64.763  0  237 MET   A CE  1 ? 
ATOM   1807 N  N   . PHE   B 1 128 ? -15.847 -12.210 -33.878 1.000 37.896  0  238 PHE   A N   1 ? 
ATOM   1808 C  CA  . PHE   B 1 128 ? -17.009 -12.115 -33.004 1.000 39.532  0  238 PHE   A CA  1 ? 
ATOM   1809 C  C   . PHE   B 1 128 ? -16.586 -12.360 -31.552 1.000 34.786  0  238 PHE   A C   1 ? 
ATOM   1810 O  O   . PHE   B 1 128 ? -17.070 -11.690 -30.646 1.000 35.683  0  238 PHE   A O   1 ? 
ATOM   1811 C  CB  . PHE   B 1 128 ? -18.097 -13.102 -33.432 1.000 44.645  0  238 PHE   A CB  1 ? 
ATOM   1812 C  CG  . PHE   B 1 128 ? -19.413 -12.932 -32.685 1.000 45.413  0  238 PHE   A CG  1 ? 
ATOM   1813 C  CD1 . PHE   B 1 128 ? -19.609 -13.523 -31.437 1.000 46.891  0  238 PHE   A CD1 1 ? 
ATOM   1814 C  CD2 . PHE   B 1 128 ? -20.450 -12.174 -33.225 1.000 48.409  0  238 PHE   A CD2 1 ? 
ATOM   1815 C  CE1 . PHE   B 1 128 ? -20.802 -13.351 -30.749 1.000 48.264  0  238 PHE   A CE1 1 ? 
ATOM   1816 C  CE2 . PHE   B 1 128 ? -21.641 -12.006 -32.532 1.000 51.760  0  238 PHE   A CE2 1 ? 
ATOM   1817 C  CZ  . PHE   B 1 128 ? -21.815 -12.594 -31.297 1.000 51.964  0  238 PHE   A CZ  1 ? 
ATOM   1818 N  N   . ILE   B 1 129 ? -15.713 -13.358 -31.345 1.000 36.515  0  239 ILE   A N   1 ? 
ATOM   1819 C  CA  . ILE   B 1 129 ? -15.258 -13.729 -30.011 1.000 38.068  0  239 ILE   A CA  1 ? 
ATOM   1820 C  C   . ILE   B 1 129 ? -14.445 -12.580 -29.411 1.000 37.226  0  239 ILE   A C   1 ? 
ATOM   1821 O  O   . ILE   B 1 129 ? -14.684 -12.178 -28.271 1.000 36.389  0  239 ILE   A O   1 ? 
ATOM   1822 C  CB  . ILE   B 1 129 ? -14.459 -15.047 -30.048 1.000 35.930  0  239 ILE   A CB  1 ? 
ATOM   1823 C  CG1 . ILE   B 1 129 ? -15.383 -16.245 -30.302 1.000 33.985  0  239 ILE   A CG1 1 ? 
ATOM   1824 C  CG2 . ILE   B 1 129 ? -13.637 -15.229 -28.765 1.000 36.876  0  239 ILE   A CG2 1 ? 
ATOM   1825 C  CD1 . ILE   B 1 129 ? -14.665 -17.580 -30.407 1.000 38.391  0  239 ILE   A CD1 1 ? 
ATOM   1826 N  N   . THR   B 1 130 ? -13.472 -12.075 -30.182 1.000 34.691  0  240 THR   A N   1 ? 
ATOM   1827 C  CA  . THR   B 1 130 ? -12.630 -10.973 -29.741 1.000 35.077  0  240 THR   A CA  1 ? 
ATOM   1828 C  C   . THR   B 1 130 ? -13.507 -9.771  -29.382 1.000 37.297  0  240 THR   A C   1 ? 
ATOM   1829 O  O   . THR   B 1 130 ? -13.278 -9.112  -28.371 1.000 40.684  0  240 THR   A O   1 ? 
ATOM   1830 C  CB  . THR   B 1 130 ? -11.619 -10.626 -30.834 1.000 39.790  0  240 THR   A CB  1 ? 
ATOM   1831 O  OG1 . THR   B 1 130 ? -10.812 -11.791 -30.976 1.000 42.331  0  240 THR   A OG1 1 ? 
ATOM   1832 C  CG2 . THR   B 1 130 ? -10.746 -9.435  -30.472 1.000 41.888  0  240 THR   A CG2 1 ? 
ATOM   1833 N  N   . ALA   B 1 131 ? -14.504 -9.493  -30.228 1.000 34.294  0  241 ALA   A N   1 ? 
ATOM   1834 C  CA  . ALA   B 1 131 ? -15.398 -8.366  -30.019 1.000 37.649  0  241 ALA   A CA  1 ? 
ATOM   1835 C  C   . ALA   B 1 131 ? -16.142 -8.522  -28.690 1.000 35.016  0  241 ALA   A C   1 ? 
ATOM   1836 O  O   . ALA   B 1 131 ? -16.169 -7.598  -27.883 1.000 28.969  0  241 ALA   A O   1 ? 
ATOM   1837 C  CB  . ALA   B 1 131 ? -16.363 -8.249  -31.184 1.000 39.626  0  241 ALA   A CB  1 ? 
ATOM   1838 N  N   . PHE   B 1 132 ? -16.715 -9.714  -28.466 1.000 30.421  0  242 PHE   A N   1 ? 
ATOM   1839 C  CA  . PHE   B 1 132 ? -17.562 -9.960  -27.309 1.000 35.866  0  242 PHE   A CA  1 ? 
ATOM   1840 C  C   . PHE   B 1 132 ? -16.742 -9.879  -26.012 1.000 32.892  0  242 PHE   A C   1 ? 
ATOM   1841 O  O   . PHE   B 1 132 ? -17.147 -9.211  -25.063 1.000 35.184  0  242 PHE   A O   1 ? 
ATOM   1842 C  CB  . PHE   B 1 132 ? -18.260 -11.316 -27.424 1.000 34.747  0  242 PHE   A CB  1 ? 
ATOM   1843 C  CG  . PHE   B 1 132 ? -18.977 -11.730 -26.150 1.000 38.392  0  242 PHE   A CG  1 ? 
ATOM   1844 C  CD1 . PHE   B 1 132 ? -20.245 -11.241 -25.853 1.000 40.473  0  242 PHE   A CD1 1 ? 
ATOM   1845 C  CD2 . PHE   B 1 132 ? -18.351 -12.551 -25.215 1.000 43.012  0  242 PHE   A CD2 1 ? 
ATOM   1846 C  CE1 . PHE   B 1 132 ? -20.882 -11.596 -24.675 1.000 48.897  0  242 PHE   A CE1 1 ? 
ATOM   1847 C  CE2 . PHE   B 1 132 ? -18.989 -12.897 -24.038 1.000 45.079  0  242 PHE   A CE2 1 ? 
ATOM   1848 C  CZ  . PHE   B 1 132 ? -20.255 -12.425 -23.772 1.000 47.789  0  242 PHE   A CZ  1 ? 
ATOM   1849 N  N   . LEU   B 1 133 ? -15.617 -10.599 -25.967 1.000 30.865  0  243 LEU   A N   1 ? 
ATOM   1850 C  CA  . LEU   B 1 133 ? -14.817 -10.706 -24.748 1.000 39.081  0  243 LEU   A CA  1 ? 
ATOM   1851 C  C   . LEU   B 1 133 ? -14.415 -9.313  -24.242 1.000 39.145  0  243 LEU   A C   1 ? 
ATOM   1852 O  O   . LEU   B 1 133 ? -14.334 -9.091  -23.034 1.000 47.138  0  243 LEU   A O   1 ? 
ATOM   1853 C  CB  . LEU   B 1 133 ? -13.594 -11.587 -24.999 1.000 40.213  0  243 LEU   A CB  1 ? 
ATOM   1854 C  CG  . LEU   B 1 133 ? -13.874 -13.073 -25.263 1.000 41.356  0  243 LEU   A CG  1 ? 
ATOM   1855 C  CD1 . LEU   B 1 133 ? -12.599 -13.791 -25.672 1.000 45.657  0  243 LEU   A CD1 1 ? 
ATOM   1856 C  CD2 . LEU   B 1 133 ? -14.499 -13.750 -24.058 1.000 39.257  0  243 LEU   A CD2 1 ? 
ATOM   1857 N  N   . ASN   B 1 134 ? -14.194 -8.377  -25.173 1.000 39.262  0  244 ASN   A N   1 ? 
ATOM   1858 C  CA  . ASN   B 1 134 ? -13.783 -7.022  -24.823 1.000 43.708  0  244 ASN   A CA  1 ? 
ATOM   1859 C  C   . ASN   B 1 134 ? -14.971 -6.226  -24.264 1.000 44.358  0  244 ASN   A C   1 ? 
ATOM   1860 O  O   . ASN   B 1 134 ? -14.879 -5.667  -23.172 1.000 56.558  0  244 ASN   A O   1 ? 
ATOM   1861 C  CB  . ASN   B 1 134 ? -13.111 -6.332  -26.002 1.000 40.017  0  244 ASN   A CB  1 ? 
ATOM   1862 C  CG  . ASN   B 1 134 ? -11.675 -6.777  -26.165 1.000 39.232  0  244 ASN   A CG  1 ? 
ATOM   1863 O  OD1 . ASN   B 1 134 ? -10.812 -6.379  -25.378 1.000 38.943  0  244 ASN   A OD1 1 ? 
ATOM   1864 N  ND2 . ASN   B 1 134 ? -11.398 -7.596  -27.169 1.000 41.827  0  244 ASN   A ND2 1 ? 
ATOM   1865 N  N   . ILE   B 1 135 ? -16.091 -6.207  -25.005 1.000 36.588  0  245 ILE   A N   1 ? 
ATOM   1866 C  CA  . ILE   B 1 135 ? -17.236 -5.367  -24.650 1.000 36.872  0  245 ILE   A CA  1 ? 
ATOM   1867 C  C   . ILE   B 1 135 ? -17.915 -5.904  -23.386 1.000 33.746  0  245 ILE   A C   1 ? 
ATOM   1868 O  O   . ILE   B 1 135 ? -18.423 -5.125  -22.583 1.000 36.730  0  245 ILE   A O   1 ? 
ATOM   1869 C  CB  . ILE   B 1 135 ? -18.237 -5.242  -25.825 1.000 38.805  0  245 ILE   A CB  1 ? 
ATOM   1870 C  CG1 . ILE   B 1 135 ? -18.903 -6.597  -26.170 1.000 39.401  0  245 ILE   A CG1 1 ? 
ATOM   1871 C  CG2 . ILE   B 1 135 ? -17.568 -4.604  -27.048 1.000 36.945  0  245 ILE   A CG2 1 ? 
ATOM   1872 C  CD1 . ILE   B 1 135 ? -19.900 -6.530  -27.315 1.000 41.090  0  245 ILE   A CD1 1 ? 
ATOM   1873 N  N   . ALA   B 1 136 ? -17.907 -7.237  -23.213 1.000 31.892  0  246 ALA   A N   1 ? 
ATOM   1874 C  CA  . ALA   B 1 136 ? -18.677 -7.889  -22.156 1.000 35.968  0  246 ALA   A CA  1 ? 
ATOM   1875 C  C   . ALA   B 1 136 ? -18.194 -7.449  -20.767 1.000 40.090  0  246 ALA   A C   1 ? 
ATOM   1876 O  O   . ALA   B 1 136 ? -18.994 -7.325  -19.843 1.000 43.798  0  246 ALA   A O   1 ? 
ATOM   1877 C  CB  . ALA   B 1 136 ? -18.596 -9.390  -22.312 1.000 38.336  0  246 ALA   A CB  1 ? 
ATOM   1878 N  N   . LEU   B 1 137 ? -16.888 -7.183  -20.644 1.000 42.806  0  247 LEU   A N   1 ? 
ATOM   1879 C  CA  . LEU   B 1 137 ? -16.275 -6.876  -19.358 1.000 43.527  0  247 LEU   A CA  1 ? 
ATOM   1880 C  C   . LEU   B 1 137 ? -16.593 -5.438  -18.926 1.000 40.840  0  247 LEU   A C   1 ? 
ATOM   1881 O  O   . LEU   B 1 137 ? -16.368 -5.084  -17.773 1.000 48.940  0  247 LEU   A O   1 ? 
ATOM   1882 C  CB  . LEU   B 1 137 ? -14.766 -7.103  -19.460 1.000 54.625  0  247 LEU   A CB  1 ? 
ATOM   1883 C  CG  . LEU   B 1 137 ? -14.312 -8.556  -19.653 1.000 57.798  0  247 LEU   A CG  1 ? 
ATOM   1884 C  CD1 . LEU   B 1 137 ? -12.875 -8.617  -20.137 1.000 55.945  0  247 LEU   A CD1 1 ? 
ATOM   1885 C  CD2 . LEU   B 1 137 ? -14.470 -9.350  -18.368 1.000 50.079  0  247 LEU   A CD2 1 ? 
ATOM   1886 N  N   . GLN   B 1 138 ? -17.116 -4.616  -19.853 1.000 39.870  0  248 GLN   A N   1 ? 
ATOM   1887 C  CA  . GLN   B 1 138 ? -17.301 -3.190  -19.587 1.000 41.664  0  248 GLN   A CA  1 ? 
ATOM   1888 C  C   . GLN   B 1 138 ? -18.785 -2.852  -19.379 1.000 39.351  0  248 GLN   A C   1 ? 
ATOM   1889 O  O   . GLN   B 1 138 ? -19.096 -1.879  -18.704 1.000 41.879  0  248 GLN   A O   1 ? 
ATOM   1890 C  CB  . GLN   B 1 138 ? -16.698 -2.355  -20.716 1.000 50.197  0  248 GLN   A CB  1 ? 
ATOM   1891 C  CG  . GLN   B 1 138 ? -15.264 -2.745  -21.073 1.000 68.113  0  248 GLN   A CG  1 ? 
ATOM   1892 C  CD  . GLN   B 1 138 ? -14.560 -1.719  -21.939 1.000 85.221  0  248 GLN   A CD  1 ? 
ATOM   1893 O  OE1 . GLN   B 1 138 ? -15.103 -1.236  -22.939 1.000 79.216  0  248 GLN   A OE1 1 ? 
ATOM   1894 N  NE2 . GLN   B 1 138 ? -13.350 -1.347  -21.540 1.000 90.563  0  248 GLN   A NE2 1 ? 
ATOM   1895 N  N   . LEU   B 1 139 ? -19.691 -3.663  -19.955 1.000 41.458  0  249 LEU   A N   1 ? 
ATOM   1896 C  CA  . LEU   B 1 139 ? -21.121 -3.353  -19.944 1.000 43.643  0  249 LEU   A CA  1 ? 
ATOM   1897 C  C   . LEU   B 1 139 ? -21.777 -3.895  -18.673 1.000 39.574  0  249 LEU   A C   1 ? 
ATOM   1898 O  O   . LEU   B 1 139 ? -21.396 -4.951  -18.172 1.000 37.116  0  249 LEU   A O   1 ? 
ATOM   1899 C  CB  . LEU   B 1 139 ? -21.801 -3.921  -21.191 1.000 51.382  0  249 LEU   A CB  1 ? 
ATOM   1900 C  CG  . LEU   B 1 139 ? -21.577 -3.152  -22.495 1.000 57.855  0  249 LEU   A CG  1 ? 
ATOM   1901 C  CD1 . LEU   B 1 139 ? -22.231 -3.893  -23.644 1.000 64.544  0  249 LEU   A CD1 1 ? 
ATOM   1902 C  CD2 . LEU   B 1 139 ? -22.107 -1.721  -22.411 1.000 54.462  0  249 LEU   A CD2 1 ? 
ATOM   1903 N  N   . PRO   B 1 140 ? -22.831 -3.212  -18.152 1.000 38.687  0  250 PRO   A N   1 ? 
ATOM   1904 C  CA  . PRO   B 1 140 ? -23.612 -3.739  -17.030 1.000 40.200  0  250 PRO   A CA  1 ? 
ATOM   1905 C  C   . PRO   B 1 140 ? -24.355 -5.021  -17.405 1.000 41.747  0  250 PRO   A C   1 ? 
ATOM   1906 O  O   . PRO   B 1 140 ? -24.763 -5.191  -18.556 1.000 38.824  0  250 PRO   A O   1 ? 
ATOM   1907 C  CB  . PRO   B 1 140 ? -24.589 -2.585  -16.677 1.000 36.870  0  250 PRO   A CB  1 ? 
ATOM   1908 C  CG  . PRO   B 1 140 ? -23.973 -1.350  -17.321 1.000 34.409  0  250 PRO   A CG  1 ? 
ATOM   1909 C  CD  . PRO   B 1 140 ? -23.241 -1.857  -18.539 1.000 33.464  0  250 PRO   A CD  1 ? 
ATOM   1910 N  N   . CYS   B 1 141 ? -24.559 -5.898  -16.408 1.000 38.454  0  251 CYS   A N   1 ? 
ATOM   1911 C  CA  . CYS   B 1 141 ? -25.260 -7.159  -16.615 1.000 37.070  0  251 CYS   A CA  1 ? 
ATOM   1912 C  C   . CYS   B 1 141 ? -26.720 -7.032  -16.173 1.000 37.745  0  251 CYS   A C   1 ? 
ATOM   1913 O  O   . CYS   B 1 141 ? -27.469 -8.003  -16.233 1.000 43.200  0  251 CYS   A O   1 ? 
ATOM   1914 C  CB  . CYS   B 1 141 ? -24.562 -8.303  -15.889 1.000 37.051  0  251 CYS   A CB  1 ? 
ATOM   1915 S  SG  . CYS   B 1 141 ? -24.509 -8.099  -14.092 1.000 45.079  0  251 CYS   A SG  1 ? 
ATOM   1916 N  N   . GLU   B 1 142 ? -27.104 -5.822  -15.724 1.000 46.343  0  252 GLU   A N   1 ? 
ATOM   1917 C  CA  . GLU   B 1 142 ? -28.477 -5.521  -15.334 1.000 49.047  0  252 GLU   A CA  1 ? 
ATOM   1918 C  C   . GLU   B 1 142 ? -28.846 -4.130  -15.855 1.000 50.756  0  252 GLU   A C   1 ? 
ATOM   1919 O  O   . GLU   B 1 142 ? -28.006 -3.228  -15.869 1.000 46.814  0  252 GLU   A O   1 ? 
ATOM   1920 C  CB  . GLU   B 1 142 ? -28.623 -5.599  -13.811 1.000 43.191  0  252 GLU   A CB  1 ? 
ATOM   1921 C  CG  . GLU   B 1 142 ? -28.463 -7.015  -13.259 1.000 47.590  0  252 GLU   A CG  1 ? 
ATOM   1922 C  CD  . GLU   B 1 142 ? -29.587 -7.975  -13.624 1.000 53.095  0  252 GLU   A CD  1 ? 
ATOM   1923 O  OE1 . GLU   B 1 142 ? -30.680 -7.500  -14.004 1.000 57.318  0  252 GLU   A OE1 1 ? 
ATOM   1924 O  OE2 . GLU   B 1 142 ? -29.346 -9.201  -13.590 1.000 42.465  0  252 GLU   A OE2 1 ? 
ATOM   1925 N  N   . SER   B 1 143 ? -30.110 -3.975  -16.290 1.000 48.367  0  253 SER   A N   1 ? 
ATOM   1926 C  CA  . SER   B 1 143 ? -30.589 -2.723  -16.872 1.000 52.963  0  253 SER   A CA  1 ? 
ATOM   1927 C  C   . SER   B 1 143 ? -31.686 -2.099  -16.005 1.000 49.041  0  253 SER   A C   1 ? 
ATOM   1928 O  O   . SER   B 1 143 ? -31.819 -0.877  -15.969 1.000 54.435  0  253 SER   A O   1 ? 
ATOM   1929 C  CB  . SER   B 1 143 ? -31.075 -2.933  -18.280 1.000 54.887  0  253 SER   A CB  1 ? 
ATOM   1930 O  OG  . SER   B 1 143 ? -32.161 -3.845  -18.315 1.000 57.269  0  253 SER   A OG  1 ? 
ATOM   1931 N  N   . SER   B 1 144 ? -32.501 -2.950  -15.357 1.000 46.792  0  254 SER   A N   1 ? 
ATOM   1932 C  CA  . SER   B 1 144 ? -33.619 -2.490  -14.540 1.000 52.613  0  254 SER   A CA  1 ? 
ATOM   1933 C  C   . SER   B 1 144 ? -33.154 -1.388  -13.584 1.000 55.576  0  254 SER   A C   1 ? 
ATOM   1934 O  O   . SER   B 1 144 ? -32.340 -1.634  -12.698 1.000 57.288  0  254 SER   A O   1 ? 
ATOM   1935 C  CB  . SER   B 1 144 ? -34.247 -3.635  -13.788 1.000 57.236  0  254 SER   A CB  1 ? 
ATOM   1936 O  OG  . SER   B 1 144 ? -35.355 -3.192  -13.017 1.000 63.975  0  254 SER   A OG  1 ? 
ATOM   1937 N  N   . ALA   B 1 145 ? -33.725 -0.186  -13.752 1.000 54.413  0  255 ALA   A N   1 ? 
ATOM   1938 C  CA  . ALA   B 1 145 ? -33.289 0.998   -13.021 1.000 62.371  0  255 ALA   A CA  1 ? 
ATOM   1939 C  C   . ALA   B 1 145 ? -33.462 0.799   -11.513 1.000 63.629  0  255 ALA   A C   1 ? 
ATOM   1940 O  O   . ALA   B 1 145 ? -32.669 1.317   -10.727 1.000 52.407  0  255 ALA   A O   1 ? 
ATOM   1941 C  CB  . ALA   B 1 145 ? -34.052 2.210   -13.508 1.000 65.734  0  255 ALA   A CB  1 ? 
ATOM   1942 N  N   . VAL   B 1 146 ? -34.526 0.076   -11.123 1.000 63.840  0  256 VAL   A N   1 ? 
ATOM   1943 C  CA  . VAL   B 1 146 ? -34.811 -0.190  -9.715  1.000 60.230  0  256 VAL   A CA  1 ? 
ATOM   1944 C  C   . VAL   B 1 146 ? -33.713 -1.097  -9.141  1.000 50.082  0  256 VAL   A C   1 ? 
ATOM   1945 O  O   . VAL   B 1 146 ? -33.253 -0.880  -8.021  1.000 47.082  0  256 VAL   A O   1 ? 
ATOM   1946 C  CB  . VAL   B 1 146 ? -36.222 -0.791  -9.491  1.000 62.336  0  256 VAL   A CB  1 ? 
ATOM   1947 C  CG1 . VAL   B 1 146 ? -36.490 -2.016  -10.365 1.000 70.429  0  256 VAL   A CG1 1 ? 
ATOM   1948 C  CG2 . VAL   B 1 146 ? -36.476 -1.118  -8.020  1.000 62.768  0  256 VAL   A CG2 1 ? 
ATOM   1949 N  N   . VAL   B 1 147 ? -33.291 -2.101  -9.927  1.000 41.498  0  257 VAL   A N   1 ? 
ATOM   1950 C  CA  . VAL   B 1 147 ? -32.240 -3.019  -9.509  1.000 40.370  0  257 VAL   A CA  1 ? 
ATOM   1951 C  C   . VAL   B 1 147 ? -30.926 -2.244  -9.406  1.000 45.038  0  257 VAL   A C   1 ? 
ATOM   1952 O  O   . VAL   B 1 147 ? -30.268 -2.268  -8.368  1.000 44.220  0  257 VAL   A O   1 ? 
ATOM   1953 C  CB  . VAL   B 1 147 ? -32.110 -4.221  -10.473 1.000 44.873  0  257 VAL   A CB  1 ? 
ATOM   1954 C  CG1 . VAL   B 1 147 ? -30.904 -5.098  -10.144 1.000 42.022  0  257 VAL   A CG1 1 ? 
ATOM   1955 C  CG2 . VAL   B 1 147 ? -33.385 -5.061  -10.506 1.000 49.560  0  257 VAL   A CG2 1 ? 
ATOM   1956 N  N   . VAL   B 1 148 ? -30.596 -1.507  -10.473 1.000 48.131  0  258 VAL   A N   1 ? 
ATOM   1957 C  CA  . VAL   B 1 148 ? -29.331 -0.793  -10.569 1.000 51.629  0  258 VAL   A CA  1 ? 
ATOM   1958 C  C   . VAL   B 1 148 ? -29.233 0.234   -9.438  1.000 52.939  0  258 VAL   A C   1 ? 
ATOM   1959 O  O   . VAL   B 1 148 ? -28.189 0.355   -8.801  1.000 51.403  0  258 VAL   A O   1 ? 
ATOM   1960 C  CB  . VAL   B 1 148 ? -29.168 -0.127  -11.952 1.000 50.755  0  258 VAL   A CB  1 ? 
ATOM   1961 C  CG1 . VAL   B 1 148 ? -27.947 0.785   -12.005 1.000 54.939  0  258 VAL   A CG1 1 ? 
ATOM   1962 C  CG2 . VAL   B 1 148 ? -29.106 -1.160  -13.075 1.000 53.852  0  258 VAL   A CG2 1 ? 
ATOM   1963 N  N   . SER   B 1 149 ? -30.326 0.979   -9.210  1.000 52.377  0  259 SER   A N   1 ? 
ATOM   1964 C  CA  . SER   B 1 149 ? -30.355 2.019   -8.188  1.000 60.765  0  259 SER   A CA  1 ? 
ATOM   1965 C  C   . SER   B 1 149 ? -30.034 1.424   -6.814  1.000 60.608  0  259 SER   A C   1 ? 
ATOM   1966 O  O   . SER   B 1 149 ? -29.242 1.988   -6.062  1.000 59.203  0  259 SER   A O   1 ? 
ATOM   1967 C  CB  . SER   B 1 149 ? -31.685 2.731   -8.175  1.000 61.935  0  259 SER   A CB  1 ? 
ATOM   1968 O  OG  . SER   B 1 149 ? -32.750 1.816   -7.955  1.000 65.883  0  259 SER   A OG  1 ? 
ATOM   1969 N  N   . GLY   B 1 150 ? -30.658 0.277   -6.506  1.000 57.166  0  260 GLY   A N   1 ? 
ATOM   1970 C  CA  . GLY   B 1 150 ? -30.458 -0.399  -5.232  1.000 53.750  0  260 GLY   A CA  1 ? 
ATOM   1971 C  C   . GLY   B 1 150 ? -29.031 -0.935  -5.090  1.000 51.605  0  260 GLY   A C   1 ? 
ATOM   1972 O  O   . GLY   B 1 150 ? -28.385 -0.717  -4.067  1.000 52.277  0  260 GLY   A O   1 ? 
ATOM   1973 N  N   . LEU   B 1 151 ? -28.548 -1.627  -6.135  1.000 43.198  0  261 LEU   A N   1 ? 
ATOM   1974 C  CA  . LEU   B 1 151 ? -27.226 -2.245  -6.113  1.000 42.723  0  261 LEU   A CA  1 ? 
ATOM   1975 C  C   . LEU   B 1 151 ? -26.138 -1.171  -6.003  1.000 39.251  0  261 LEU   A C   1 ? 
ATOM   1976 O  O   . LEU   B 1 151 ? -25.066 -1.436  -5.465  1.000 41.339  0  261 LEU   A O   1 ? 
ATOM   1977 C  CB  . LEU   B 1 151 ? -27.022 -3.116  -7.355  1.000 43.032  0  261 LEU   A CB  1 ? 
ATOM   1978 C  CG  . LEU   B 1 151 ? -27.937 -4.342  -7.483  1.000 46.011  0  261 LEU   A CG  1 ? 
ATOM   1979 C  CD1 . LEU   B 1 151 ? -27.627 -5.104  -8.756  1.000 43.081  0  261 LEU   A CD1 1 ? 
ATOM   1980 C  CD2 . LEU   B 1 151 ? -27.831 -5.259  -6.276  1.000 47.984  0  261 LEU   A CD2 1 ? 
ATOM   1981 N  N   . ARG   B 1 152 ? -26.423 0.038   -6.520  1.000 38.840  0  262 ARG   A N   1 ? 
ATOM   1982 C  CA  . ARG   B 1 152 ? -25.457 1.132   -6.496  1.000 44.286  0  262 ARG   A CA  1 ? 
ATOM   1983 C  C   . ARG   B 1 152 ? -25.172 1.566   -5.057  1.000 42.959  0  262 ARG   A C   1 ? 
ATOM   1984 O  O   . ARG   B 1 152 ? -24.060 2.001   -4.755  1.000 48.517  0  262 ARG   A O   1 ? 
ATOM   1985 C  CB  . ARG   B 1 152 ? -25.917 2.333   -7.334  1.000 48.679  0  262 ARG   A CB  1 ? 
ATOM   1986 C  CG  . ARG   B 1 152 ? -25.584 2.224   -8.816  1.000 50.369  0  262 ARG   A CG  1 ? 
ATOM   1987 C  CD  . ARG   B 1 152 ? -25.855 3.517   -9.562  1.000 47.581  0  262 ARG   A CD  1 ? 
ATOM   1988 N  NE  . ARG   B 1 152 ? -25.352 3.468   -10.943 1.000 58.060  0  262 ARG   A NE  1 ? 
ATOM   1989 C  CZ  . ARG   B 1 152 ? -26.078 3.684   -12.048 1.000 58.263  0  262 ARG   A CZ  1 ? 
ATOM   1990 N  NH1 . ARG   B 1 152 ? -27.363 3.990   -11.958 1.000 58.689  0  262 ARG   A NH1 1 ? 
ATOM   1991 N  NH2 . ARG   B 1 152 ? -25.504 3.612   -13.239 1.000 56.269  0  262 ARG   A NH2 1 ? 
ATOM   1992 N  N   . THR   B 1 153 ? -26.166 1.413   -4.165  1.000 37.730  0  263 THR   A N   1 ? 
ATOM   1993 C  CA  . THR   B 1 153 ? -26.028 1.857   -2.779  1.000 40.980  0  263 THR   A CA  1 ? 
ATOM   1994 C  C   . THR   B 1 153 ? -25.136 0.885   -1.993  1.000 40.862  0  263 THR   A C   1 ? 
ATOM   1995 O  O   . THR   B 1 153 ? -24.771 1.175   -0.858  1.000 39.045  0  263 THR   A O   1 ? 
ATOM   1996 C  CB  . THR   B 1 153 ? -27.405 1.986   -2.123  1.000 39.225  0  263 THR   A CB  1 ? 
ATOM   1997 O  OG1 . THR   B 1 153 ? -27.941 0.670   -2.082  1.000 49.444  0  263 THR   A OG1 1 ? 
ATOM   1998 C  CG2 . THR   B 1 153 ? -28.329 2.929   -2.870  1.000 37.716  0  263 THR   A CG2 1 ? 
ATOM   1999 N  N   . LEU   B 1 154 ? -24.821 -0.279  -2.595  1.000 42.160  0  264 LEU   A N   1 ? 
ATOM   2000 C  CA  . LEU   B 1 154 ? -24.095 -1.340  -1.905  1.000 40.024  0  264 LEU   A CA  1 ? 
ATOM   2001 C  C   . LEU   B 1 154 ? -22.620 -1.358  -2.323  1.000 40.341  0  264 LEU   A C   1 ? 
ATOM   2002 O  O   . LEU   B 1 154 ? -21.793 -1.953  -1.633  1.000 38.351  0  264 LEU   A O   1 ? 
ATOM   2003 C  CB  . LEU   B 1 154 ? -24.762 -2.684  -2.202  1.000 38.977  0  264 LEU   A CB  1 ? 
ATOM   2004 C  CG  . LEU   B 1 154 ? -26.191 -2.866  -1.681  1.000 35.699  0  264 LEU   A CG  1 ? 
ATOM   2005 C  CD1 . LEU   B 1 154 ? -26.749 -4.196  -2.155  1.000 34.488  0  264 LEU   A CD1 1 ? 
ATOM   2006 C  CD2 . LEU   B 1 154 ? -26.257 -2.771  -0.162  1.000 35.462  0  264 LEU   A CD2 1 ? 
ATOM   2007 N  N   . VAL   B 1 155 ? -22.305 -0.751  -3.475  1.000 38.967  0  265 VAL   A N   1 ? 
ATOM   2008 C  CA  . VAL   B 1 155 ? -20.959 -0.830  -4.033  1.000 40.498  0  265 VAL   A CA  1 ? 
ATOM   2009 C  C   . VAL   B 1 155 ? -19.981 -0.152  -3.066  1.000 44.839  0  265 VAL   A C   1 ? 
ATOM   2010 O  O   . VAL   B 1 155 ? -20.219 0.971   -2.631  1.000 46.923  0  265 VAL   A O   1 ? 
ATOM   2011 C  CB  . VAL   B 1 155 ? -20.875 -0.201  -5.440  1.000 39.394  0  265 VAL   A CB  1 ? 
ATOM   2012 C  CG1 . VAL   B 1 155 ? -19.468 -0.305  -6.027  1.000 42.831  0  265 VAL   A CG1 1 ? 
ATOM   2013 C  CG2 . VAL   B 1 155 ? -21.892 -0.814  -6.397  1.000 43.772  0  265 VAL   A CG2 1 ? 
ATOM   2014 N  N   . PRO   B 1 156 ? -18.864 -0.827  -2.684  1.000 54.693  0  266 PRO   A N   1 ? 
ATOM   2015 C  CA  . PRO   B 1 156 ? -17.837 -0.204  -1.848  1.000 55.743  0  266 PRO   A CA  1 ? 
ATOM   2016 C  C   . PRO   B 1 156 ? -16.889 0.665   -2.667  1.000 56.963  0  266 PRO   A C   1 ? 
ATOM   2017 O  O   . PRO   B 1 156 ? -16.708 1.834   -2.273  1.000 70.685  0  266 PRO   A O   1 ? 
ATOM   2018 C  CB  . PRO   B 1 156 ? -17.128 -1.421  -1.220  1.000 51.152  0  266 PRO   A CB  1 ? 
ATOM   2019 C  CG  . PRO   B 1 156 ? -17.233 -2.497  -2.291  1.000 52.039  0  266 PRO   A CG  1 ? 
ATOM   2020 C  CD  . PRO   B 1 156 ? -18.567 -2.236  -2.990  1.000 54.651  0  266 PRO   A CD  1 ? 
ATOM   2021 N  N   . PRO   C 1 30  ? -5.486  -3.767  25.104  1.000 62.633  0  140 PRO   B N   1 ? 
ATOM   2022 C  CA  . PRO   C 1 30  ? -6.817  -4.364  25.181  1.000 59.553  0  140 PRO   B CA  1 ? 
ATOM   2023 C  C   . PRO   C 1 30  ? -6.814  -5.618  26.058  1.000 49.551  0  140 PRO   B C   1 ? 
ATOM   2024 O  O   . PRO   C 1 30  ? -6.025  -6.533  25.836  1.000 51.172  0  140 PRO   B O   1 ? 
ATOM   2025 C  CB  . PRO   C 1 30  ? -7.198  -4.673  23.706  1.000 62.296  0  140 PRO   B CB  1 ? 
ATOM   2026 C  CG  . PRO   C 1 30  ? -5.872  -4.684  22.979  1.000 61.063  0  140 PRO   B CG  1 ? 
ATOM   2027 C  CD  . PRO   C 1 30  ? -5.020  -3.685  23.729  1.000 63.740  0  140 PRO   B CD  1 ? 
ATOM   2028 N  N   . LYS   C 1 31  ? -7.692  -5.632  27.070  1.000 50.778  0  141 LYS   B N   1 ? 
ATOM   2029 C  CA  . LYS   C 1 31  ? -7.803  -6.763  27.979  1.000 47.100  0  141 LYS   B CA  1 ? 
ATOM   2030 C  C   . LYS   C 1 31  ? -8.497  -7.915  27.262  1.000 42.773  0  141 LYS   B C   1 ? 
ATOM   2031 O  O   . LYS   C 1 31  ? -9.562  -7.731  26.676  1.000 45.563  0  141 LYS   B O   1 ? 
ATOM   2032 C  CB  . LYS   C 1 31  ? -8.585  -6.384  29.241  1.000 50.932  0  141 LYS   B CB  1 ? 
ATOM   2033 C  CG  . LYS   C 1 31  ? -7.891  -5.404  30.173  1.000 53.353  0  141 LYS   B CG  1 ? 
ATOM   2034 C  CD  . LYS   C 1 31  ? -8.639  -5.193  31.484  1.000 68.808  0  141 LYS   B CD  1 ? 
ATOM   2035 C  CE  . LYS   C 1 31  ? -7.946  -4.249  32.409  1.000 79.364  0  141 LYS   B CE  1 ? 
ATOM   2036 N  NZ  . LYS   C 1 31  ? -8.695  -4.075  33.655  1.000 79.785  0  141 LYS   B NZ  1 ? 
ATOM   2037 N  N   . ILE   C 1 32  ? -7.905  -9.112  27.359  1.000 39.260  0  142 ILE   B N   1 ? 
ATOM   2038 C  CA  . ILE   C 1 32  ? -8.445  -10.297 26.711  1.000 39.068  0  142 ILE   B CA  1 ? 
ATOM   2039 C  C   . ILE   C 1 32  ? -9.479  -10.937 27.638  1.000 32.694  0  142 ILE   B C   1 ? 
ATOM   2040 O  O   . ILE   C 1 32  ? -9.271  -12.034 28.151  1.000 32.058  0  142 ILE   B O   1 ? 
ATOM   2041 C  CB  . ILE   C 1 32  ? -7.317  -11.281 26.330  1.000 43.576  0  142 ILE   B CB  1 ? 
ATOM   2042 C  CG1 . ILE   C 1 32  ? -6.158  -10.570 25.609  1.000 46.273  0  142 ILE   B CG1 1 ? 
ATOM   2043 C  CG2 . ILE   C 1 32  ? -7.862  -12.450 25.502  1.000 50.100  0  142 ILE   B CG2 1 ? 
ATOM   2044 C  CD1 . ILE   C 1 32  ? -6.574  -9.799  24.367  1.000 49.349  0  142 ILE   B CD1 1 ? 
ATOM   2045 N  N   . THR   C 1 33  ? -10.604 -10.236 27.837  1.000 37.134  0  143 THR   B N   1 ? 
ATOM   2046 C  CA  . THR   C 1 33  ? -11.712 -10.762 28.619  1.000 37.226  0  143 THR   B CA  1 ? 
ATOM   2047 C  C   . THR   C 1 33  ? -12.459 -11.791 27.773  1.000 39.566  0  143 THR   B C   1 ? 
ATOM   2048 O  O   . THR   C 1 33  ? -12.241 -11.883 26.565  1.000 34.599  0  143 THR   B O   1 ? 
ATOM   2049 C  CB  . THR   C 1 33  ? -12.631 -9.621  29.064  1.000 39.610  0  143 THR   B CB  1 ? 
ATOM   2050 O  OG1 . THR   C 1 33  ? -13.141 -9.030  27.872  1.000 36.323  0  143 THR   B OG1 1 ? 
ATOM   2051 C  CG2 . THR   C 1 33  ? -11.905 -8.577  29.896  1.000 44.782  0  143 THR   B CG2 1 ? 
ATOM   2052 N  N   . LEU   C 1 34  ? -13.345 -12.554 28.425  1.000 39.038  0  144 LEU   B N   1 ? 
ATOM   2053 C  CA  . LEU   C 1 34  ? -14.147 -13.568 27.753  1.000 39.683  0  144 LEU   B CA  1 ? 
ATOM   2054 C  C   . LEU   C 1 34  ? -14.965 -12.925 26.630  1.000 36.850  0  144 LEU   B C   1 ? 
ATOM   2055 O  O   . LEU   C 1 34  ? -15.076 -13.486 25.544  1.000 38.221  0  144 LEU   B O   1 ? 
ATOM   2056 C  CB  . LEU   C 1 34  ? -15.044 -14.267 28.775  1.000 49.105  0  144 LEU   B CB  1 ? 
ATOM   2057 C  CG  . LEU   C 1 34  ? -14.331 -15.187 29.772  1.000 59.814  0  144 LEU   B CG  1 ? 
ATOM   2058 C  CD1 . LEU   C 1 34  ? -15.214 -15.493 30.972  1.000 68.211  0  144 LEU   B CD1 1 ? 
ATOM   2059 C  CD2 . LEU   C 1 34  ? -13.887 -16.476 29.093  1.000 55.258  0  144 LEU   B CD2 1 ? 
ATOM   2060 N  N   . LEU   C 1 35  ? -15.509 -11.730 26.900  1.000 35.268  0  145 LEU   B N   1 ? 
ATOM   2061 C  CA  . LEU   C 1 35  ? -16.335 -11.022 25.936  1.000 35.822  0  145 LEU   B CA  1 ? 
ATOM   2062 C  C   . LEU   C 1 35  ? -15.480 -10.594 24.739  1.000 37.317  0  145 LEU   B C   1 ? 
ATOM   2063 O  O   . LEU   C 1 35  ? -15.875 -10.795 23.592  1.000 36.279  0  145 LEU   B O   1 ? 
ATOM   2064 C  CB  . LEU   C 1 35  ? -17.009 -9.827  26.611  1.000 37.482  0  145 LEU   B CB  1 ? 
ATOM   2065 C  CG  . LEU   C 1 35  ? -18.002 -9.034  25.752  1.000 41.715  0  145 LEU   B CG  1 ? 
ATOM   2066 C  CD1 . LEU   C 1 35  ? -19.103 -9.922  25.178  1.000 42.298  0  145 LEU   B CD1 1 ? 
ATOM   2067 C  CD2 . LEU   C 1 35  ? -18.604 -7.900  26.555  1.000 40.563  0  145 LEU   B CD2 1 ? 
ATOM   2068 N  N   . THR   C 1 36  ? -14.293 -10.031 25.022  1.000 38.511  0  146 THR   B N   1 ? 
ATOM   2069 C  CA  . THR   C 1 36  ? -13.367 -9.599  23.978  1.000 35.924  0  146 THR   B CA  1 ? 
ATOM   2070 C  C   . THR   C 1 36  ? -12.989 -10.797 23.108  1.000 36.463  0  146 THR   B C   1 ? 
ATOM   2071 O  O   . THR   C 1 36  ? -12.829 -10.661 21.897  1.000 39.046  0  146 THR   B O   1 ? 
ATOM   2072 C  CB  . THR   C 1 36  ? -12.132 -8.948  24.613  1.000 40.448  0  146 THR   B CB  1 ? 
ATOM   2073 O  OG1 . THR   C 1 36  ? -12.591 -7.740  25.213  1.000 37.240  0  146 THR   B OG1 1 ? 
ATOM   2074 C  CG2 . THR   C 1 36  ? -11.051 -8.614  23.598  1.000 40.664  0  146 THR   B CG2 1 ? 
ATOM   2075 N  N   . LEU   C 1 37  ? -12.846 -11.967 23.746  1.000 33.358  0  147 LEU   B N   1 ? 
ATOM   2076 C  CA  . LEU   C 1 37  ? -12.477 -13.190 23.052  1.000 31.860  0  147 LEU   B CA  1 ? 
ATOM   2077 C  C   . LEU   C 1 37  ? -13.594 -13.586 22.076  1.000 34.694  0  147 LEU   B C   1 ? 
ATOM   2078 O  O   . LEU   C 1 37  ? -13.320 -14.046 20.966  1.000 35.361  0  147 LEU   B O   1 ? 
ATOM   2079 C  CB  . LEU   C 1 37  ? -12.211 -14.288 24.080  1.000 38.471  0  147 LEU   B CB  1 ? 
ATOM   2080 C  CG  . LEU   C 1 37  ? -11.359 -15.466 23.603  1.000 44.330  0  147 LEU   B CG  1 ? 
ATOM   2081 C  CD1 . LEU   C 1 37  ? -9.892  -15.052 23.465  1.000 44.036  0  147 LEU   B CD1 1 ? 
ATOM   2082 C  CD2 . LEU   C 1 37  ? -11.503 -16.649 24.542  1.000 47.728  0  147 LEU   B CD2 1 ? 
ATOM   2083 N  N   . ILE   C 1 38  ? -14.852 -13.406 22.509  1.000 30.369  0  148 ILE   B N   1 ? 
ATOM   2084 C  CA  . ILE   C 1 38  ? -16.011 -13.738 21.687  1.000 36.443  0  148 ILE   B CA  1 ? 
ATOM   2085 C  C   . ILE   C 1 38  ? -16.116 -12.748 20.527  1.000 32.361  0  148 ILE   B C   1 ? 
ATOM   2086 O  O   . ILE   C 1 38  ? -16.384 -13.151 19.395  1.000 31.195  0  148 ILE   B O   1 ? 
ATOM   2087 C  CB  . ILE   C 1 38  ? -17.300 -13.769 22.535  1.000 38.258  0  148 ILE   B CB  1 ? 
ATOM   2088 C  CG1 . ILE   C 1 38  ? -17.310 -14.965 23.476  1.000 41.895  0  148 ILE   B CG1 1 ? 
ATOM   2089 C  CG2 . ILE   C 1 38  ? -18.548 -13.743 21.644  1.000 40.622  0  148 ILE   B CG2 1 ? 
ATOM   2090 C  CD1 . ILE   C 1 38  ? -18.555 -15.064 24.333  1.000 49.577  0  148 ILE   B CD1 1 ? 
ATOM   2091 N  N   . LYS   C 1 39  ? -15.928 -11.451 20.826  1.000 29.121  0  149 LYS   B N   1 ? 
ATOM   2092 C  CA  . LYS   C 1 39  ? -16.059 -10.401 19.824  1.000 29.529  0  149 LYS   B CA  1 ? 
ATOM   2093 C  C   . LYS   C 1 39  ? -14.967 -10.545 18.766  1.000 29.514  0  149 LYS   B C   1 ? 
ATOM   2094 O  O   . LYS   C 1 39  ? -15.197 -10.251 17.599  1.000 32.087  0  149 LYS   B O   1 ? 
ATOM   2095 C  CB  . LYS   C 1 39  ? -16.066 -9.007  20.463  1.000 39.617  0  149 LYS   B CB  1 ? 
ATOM   2096 C  CG  . LYS   C 1 39  ? -17.442 -8.547  20.941  1.000 46.963  0  149 LYS   B CG  1 ? 
ATOM   2097 C  CD  . LYS   C 1 39  ? -17.510 -7.096  21.402  1.000 60.934  0  149 LYS   B CD  1 ? 
ATOM   2098 C  CE  . LYS   C 1 39  ? -16.929 -6.885  22.757  1.000 62.945  0  149 LYS   B CE  1 ? 
ATOM   2099 N  NZ  . LYS   C 1 39  ? -17.142 -5.515  23.228  1.000 60.226  0  149 LYS   B NZ  1 ? 
ATOM   2100 N  N   . THR   C 1 40  ? -13.795 -11.034 19.182  1.000 33.855  0  150 THR   B N   1 ? 
ATOM   2101 C  CA  . THR   C 1 40  ? -12.696 -11.291 18.261  1.000 30.248  0  150 THR   B CA  1 ? 
ATOM   2102 C  C   . THR   C 1 40  ? -13.062 -12.469 17.363  1.000 27.373  0  150 THR   B C   1 ? 
ATOM   2103 O  O   . THR   C 1 40  ? -12.798 -12.442 16.162  1.000 31.871  0  150 THR   B O   1 ? 
ATOM   2104 C  CB  . THR   C 1 40  ? -11.416 -11.553 19.054  1.000 28.883  0  150 THR   B CB  1 ? 
ATOM   2105 O  OG1 . THR   C 1 40  ? -11.182 -10.342 19.768  1.000 28.114  0  150 THR   B OG1 1 ? 
ATOM   2106 C  CG2 . THR   C 1 40  ? -10.226 -11.875 18.165  1.000 29.798  0  150 THR   B CG2 1 ? 
ATOM   2107 N  N   . ALA   C 1 41  ? -13.658 -13.506 17.967  1.000 28.949  0  151 ALA   B N   1 ? 
ATOM   2108 C  CA  . ALA   C 1 41  ? -14.088 -14.688 17.236  1.000 30.751  0  151 ALA   B CA  1 ? 
ATOM   2109 C  C   . ALA   C 1 41  ? -15.181 -14.316 16.233  1.000 30.409  0  151 ALA   B C   1 ? 
ATOM   2110 O  O   . ALA   C 1 41  ? -15.141 -14.751 15.086  1.000 31.380  0  151 ALA   B O   1 ? 
ATOM   2111 C  CB  . ALA   C 1 41  ? -14.565 -15.749 18.203  1.000 32.490  0  151 ALA   B CB  1 ? 
ATOM   2112 N  N   . GLU   C 1 42  ? -16.154 -13.506 16.683  1.000 32.639  0  152 GLU   B N   1 ? 
ATOM   2113 C  CA  . GLU   C 1 42  ? -17.260 -13.075 15.833  1.000 40.414  0  152 GLU   B CA  1 ? 
ATOM   2114 C  C   . GLU   C 1 42  ? -16.716 -12.377 14.584  1.000 38.406  0  152 GLU   B C   1 ? 
ATOM   2115 O  O   . GLU   C 1 42  ? -17.185 -12.634 13.478  1.000 43.267  0  152 GLU   B O   1 ? 
ATOM   2116 C  CB  . GLU   C 1 42  ? -18.226 -12.150 16.583  1.000 43.853  0  152 GLU   B CB  1 ? 
ATOM   2117 C  CG  . GLU   C 1 42  ? -19.093 -12.874 17.610  1.000 53.738  0  152 GLU   B CG  1 ? 
ATOM   2118 C  CD  . GLU   C 1 42  ? -20.206 -12.027 18.209  1.000 63.581  0  152 GLU   B CD  1 ? 
ATOM   2119 O  OE1 . GLU   C 1 42  ? -20.241 -11.876 19.447  1.000 67.262  0  152 GLU   B OE1 1 ? 
ATOM   2120 O  OE2 . GLU   C 1 42  ? -21.057 -11.544 17.434  1.000 79.349  0  152 GLU   B OE2 1 ? 
ATOM   2121 N  N   . HIS   C 1 43  ? -15.713 -11.508 14.774  1.000 35.750  0  153 HIS   B N   1 ? 
ATOM   2122 C  CA  . HIS   C 1 43  ? -15.143 -10.733 13.679  1.000 39.361  0  153 HIS   B CA  1 ? 
ATOM   2123 C  C   . HIS   C 1 43  ? -14.465 -11.660 12.669  1.000 37.583  0  153 HIS   B C   1 ? 
ATOM   2124 O  O   . HIS   C 1 43  ? -14.806 -11.645 11.488  1.000 40.492  0  153 HIS   B O   1 ? 
ATOM   2125 C  CB  . HIS   C 1 43  ? -14.163 -9.675  14.207  1.000 37.313  0  153 HIS   B CB  1 ? 
ATOM   2126 C  CG  . HIS   C 1 43  ? -13.509 -8.863  13.125  1.000 38.553  0  153 HIS   B CG  1 ? 
ATOM   2127 N  ND1 . HIS   C 1 43  ? -14.101 -7.754  12.557  1.000 37.733  0  153 HIS   B ND1 1 ? 
ATOM   2128 C  CD2 . HIS   C 1 43  ? -12.330 -9.017  12.490  1.000 34.115  0  153 HIS   B CD2 1 ? 
ATOM   2129 C  CE1 . HIS   C 1 43  ? -13.298 -7.257  11.625  1.000 34.819  0  153 HIS   B CE1 1 ? 
ATOM   2130 N  NE2 . HIS   C 1 43  ? -12.218 -8.008  11.569  1.000 32.793  0  153 HIS   B NE2 1 ? 
ATOM   2131 N  N   . TRP   C 1 44  ? -13.521 -12.482 13.156  1.000 32.707  0  154 TRP   B N   1 ? 
ATOM   2132 C  CA  . TRP   C 1 44  ? -12.638 -13.246 12.281  1.000 32.625  0  154 TRP   B CA  1 ? 
ATOM   2133 C  C   . TRP   C 1 44  ? -13.373 -14.407 11.617  1.000 28.201  0  154 TRP   B C   1 ? 
ATOM   2134 O  O   . TRP   C 1 44  ? -12.896 -14.950 10.624  1.000 34.136  0  154 TRP   B O   1 ? 
ATOM   2135 C  CB  . TRP   C 1 44  ? -11.405 -13.734 13.052  1.000 32.811  0  154 TRP   B CB  1 ? 
ATOM   2136 C  CG  . TRP   C 1 44  ? -10.371 -12.661 13.241  1.000 33.644  0  154 TRP   B CG  1 ? 
ATOM   2137 C  CD1 . TRP   C 1 44  ? -10.121 -11.941 14.370  1.000 34.440  0  154 TRP   B CD1 1 ? 
ATOM   2138 C  CD2 . TRP   C 1 44  ? -9.540  -12.093 12.212  1.000 35.178  0  154 TRP   B CD2 1 ? 
ATOM   2139 N  NE1 . TRP   C 1 44  ? -9.138  -11.019 14.136  1.000 36.750  0  154 TRP   B NE1 1 ? 
ATOM   2140 C  CE2 . TRP   C 1 44  ? -8.772  -11.077 12.818  1.000 35.742  0  154 TRP   B CE2 1 ? 
ATOM   2141 C  CE3 . TRP   C 1 44  ? -9.358  -12.355 10.847  1.000 34.033  0  154 TRP   B CE3 1 ? 
ATOM   2142 C  CZ2 . TRP   C 1 44  ? -7.845  -10.319 12.105  1.000 35.713  0  154 TRP   B CZ2 1 ? 
ATOM   2143 C  CZ3 . TRP   C 1 44  ? -8.449  -11.599 10.140  1.000 35.181  0  154 TRP   B CZ3 1 ? 
ATOM   2144 C  CH2 . TRP   C 1 44  ? -7.706  -10.592 10.761  1.000 39.774  0  154 TRP   B CH2 1 ? 
ATOM   2145 N  N   . ALA   C 1 45  ? -14.542 -14.764 12.153  1.000 28.602  0  155 ALA   B N   1 ? 
ATOM   2146 C  CA  . ALA   C 1 45  ? -15.371 -15.805 11.563  1.000 25.018  0  155 ALA   B CA  1 ? 
ATOM   2147 C  C   . ALA   C 1 45  ? -15.866 -15.378 10.177  1.000 25.329  0  155 ALA   B C   1 ? 
ATOM   2148 O  O   . ALA   C 1 45  ? -16.137 -16.226 9.335   1.000 32.121  0  155 ALA   B O   1 ? 
ATOM   2149 C  CB  . ALA   C 1 45  ? -16.524 -16.121 12.484  1.000 24.595  0  155 ALA   B CB  1 ? 
ATOM   2150 N  N   . ARG   C 1 46  ? -15.952 -14.052 9.946   1.000 31.438  0  156 ARG   B N   1 ? 
ATOM   2151 C  CA  . ARG   C 1 46  ? -16.528 -13.506 8.717   1.000 34.037  0  156 ARG   B CA  1 ? 
ATOM   2152 C  C   . ARG   C 1 46  ? -15.444 -13.253 7.660   1.000 33.292  0  156 ARG   B C   1 ? 
ATOM   2153 O  O   . ARG   C 1 46  ? -15.762 -13.032 6.498   1.000 38.540  0  156 ARG   B O   1 ? 
ATOM   2154 C  CB  . ARG   C 1 46  ? -17.222 -12.161 8.979   1.000 36.883  0  156 ARG   B CB  1 ? 
ATOM   2155 C  CG  . ARG   C 1 46  ? -18.197 -12.124 10.147  1.000 35.167  0  156 ARG   B CG  1 ? 
ATOM   2156 C  CD  . ARG   C 1 46  ? -18.837 -10.749 10.283  1.000 38.307  0  156 ARG   B CD  1 ? 
ATOM   2157 N  NE  . ARG   C 1 46  ? -19.458 -10.552 11.600  1.000 50.429  0  156 ARG   B NE  1 ? 
ATOM   2158 C  CZ  . ARG   C 1 46  ? -19.038 -9.691  12.545  1.000 52.645  0  156 ARG   B CZ  1 ? 
ATOM   2159 N  NH1 . ARG   C 1 46  ? -17.980 -8.915  12.336  1.000 48.384  0  156 ARG   B NH1 1 ? 
ATOM   2160 N  NH2 . ARG   C 1 46  ? -19.682 -9.618  13.700  1.000 55.787  0  156 ARG   B NH2 1 ? 
ATOM   2161 N  N   . GLN   C 1 47  ? -14.173 -13.213 8.085   1.000 38.917  0  157 GLN   B N   1 ? 
ATOM   2162 C  CA  . GLN   C 1 47  ? -13.098 -12.723 7.230   1.000 38.865  0  157 GLN   B CA  1 ? 
ATOM   2163 C  C   . GLN   C 1 47  ? -12.610 -13.824 6.294   1.000 38.533  0  157 GLN   B C   1 ? 
ATOM   2164 O  O   . GLN   C 1 47  ? -12.730 -15.007 6.595   1.000 34.345  0  157 GLN   B O   1 ? 
ATOM   2165 C  CB  . GLN   C 1 47  ? -11.912 -12.218 8.053   1.000 35.935  0  157 GLN   B CB  1 ? 
ATOM   2166 C  CG  . GLN   C 1 47  ? -12.264 -11.135 9.063   1.000 37.131  0  157 GLN   B CG  1 ? 
ATOM   2167 C  CD  . GLN   C 1 47  ? -12.985 -9.954  8.450   1.000 37.076  0  157 GLN   B CD  1 ? 
ATOM   2168 O  OE1 . GLN   C 1 47  ? -12.652 -9.493  7.351   1.000 38.408  0  157 GLN   B OE1 1 ? 
ATOM   2169 N  NE2 . GLN   C 1 47  ? -14.016 -9.482  9.136   1.000 35.881  0  157 GLN   B NE2 1 ? 
ATOM   2170 N  N   . ASP   C 1 48  ? -12.051 -13.396 5.153   1.000 47.529  0  158 ASP   B N   1 ? 
ATOM   2171 C  CA  . ASP   C 1 48  ? -11.301 -14.269 4.265   1.000 54.638  0  158 ASP   B CA  1 ? 
ATOM   2172 C  C   . ASP   C 1 48  ? -9.851  -14.295 4.743   1.000 45.230  0  158 ASP   B C   1 ? 
ATOM   2173 O  O   . ASP   C 1 48  ? -9.073  -13.400 4.420   1.000 50.492  0  158 ASP   B O   1 ? 
ATOM   2174 C  CB  . ASP   C 1 48  ? -11.427 -13.811 2.818   1.000 63.233  0  158 ASP   B CB  1 ? 
ATOM   2175 C  CG  . ASP   C 1 48  ? -10.516 -14.516 1.825   1.000 67.188  0  158 ASP   B CG  1 ? 
ATOM   2176 O  OD1 . ASP   C 1 48  ? -10.564 -15.761 1.768   1.000 72.905  0  158 ASP   B OD1 1 ? 
ATOM   2177 O  OD2 . ASP   C 1 48  ? -9.769  -13.811 1.113   1.000 85.052  0  158 ASP   B OD2 1 ? 
ATOM   2178 N  N   . ILE   C 1 49  ? -9.493  -15.350 5.483   1.000 41.055  0  159 ILE   B N   1 ? 
ATOM   2179 C  CA  . ILE   C 1 49  ? -8.242  -15.382 6.232   1.000 47.850  0  159 ILE   B CA  1 ? 
ATOM   2180 C  C   . ILE   C 1 49  ? -7.126  -16.015 5.388   1.000 44.317  0  159 ILE   B C   1 ? 
ATOM   2181 O  O   . ILE   C 1 49  ? -6.082  -16.376 5.919   1.000 45.687  0  159 ILE   B O   1 ? 
ATOM   2182 C  CB  . ILE   C 1 49  ? -8.434  -16.122 7.570   1.000 44.914  0  159 ILE   B CB  1 ? 
ATOM   2183 C  CG1 . ILE   C 1 49  ? -8.701  -17.612 7.362   1.000 42.696  0  159 ILE   B CG1 1 ? 
ATOM   2184 C  CG2 . ILE   C 1 49  ? -9.535  -15.458 8.402   1.000 49.469  0  159 ILE   B CG2 1 ? 
ATOM   2185 C  CD1 . ILE   C 1 49  ? -8.643  -18.436 8.634   1.000 50.415  0  159 ILE   B CD1 1 ? 
ATOM   2186 N  N   . ARG   C 1 50  ? -7.342  -16.109 4.072   1.000 47.690  0  160 ARG   B N   1 ? 
ATOM   2187 C  CA  . ARG   C 1 50  ? -6.340  -16.643 3.162   1.000 59.300  0  160 ARG   B CA  1 ? 
ATOM   2188 C  C   . ARG   C 1 50  ? -5.227  -15.616 2.949   1.000 58.804  0  160 ARG   B C   1 ? 
ATOM   2189 O  O   . ARG   C 1 50  ? -4.063  -15.985 2.818   1.000 61.469  0  160 ARG   B O   1 ? 
ATOM   2190 C  CB  . ARG   C 1 50  ? -6.998  -17.014 1.828   1.000 72.474  0  160 ARG   B CB  1 ? 
ATOM   2191 C  CG  . ARG   C 1 50  ? -6.043  -17.452 0.723   1.000 84.201  0  160 ARG   B CG  1 ? 
ATOM   2192 C  CD  . ARG   C 1 50  ? -6.766  -17.612 -0.610  1.000 87.901  0  160 ARG   B CD  1 ? 
ATOM   2193 N  NE  . ARG   C 1 50  ? -7.462  -16.374 -0.993  1.000 101.383 0  160 ARG   B NE  1 ? 
ATOM   2194 C  CZ  . ARG   C 1 50  ? -8.794  -16.200 -1.009  1.000 102.297 0  160 ARG   B CZ  1 ? 
ATOM   2195 N  NH1 . ARG   C 1 50  ? -9.607  -17.193 -0.676  1.000 82.631  0  160 ARG   B NH1 1 ? 
ATOM   2196 N  NH2 . ARG   C 1 50  ? -9.303  -15.024 -1.346  1.000 95.791  0  160 ARG   B NH2 1 ? 
ATOM   2197 N  N   . THR   C 1 51  ? -5.596  -14.325 2.966   1.000 63.518  0  161 THR   B N   1 ? 
ATOM   2198 C  CA  . THR   C 1 51  ? -4.720  -13.258 2.497   1.000 65.921  0  161 THR   B CA  1 ? 
ATOM   2199 C  C   . THR   C 1 51  ? -4.136  -12.463 3.672   1.000 61.679  0  161 THR   B C   1 ? 
ATOM   2200 O  O   . THR   C 1 51  ? -3.462  -11.459 3.455   1.000 76.056  0  161 THR   B O   1 ? 
ATOM   2201 C  CB  . THR   C 1 51  ? -5.510  -12.358 1.550   1.000 75.706  0  161 THR   B CB  1 ? 
ATOM   2202 O  OG1 . THR   C 1 51  ? -6.735  -12.079 2.228   1.000 67.719  0  161 THR   B OG1 1 ? 
ATOM   2203 C  CG2 . THR   C 1 51  ? -5.796  -13.027 0.217   1.000 78.289  0  161 THR   B CG2 1 ? 
ATOM   2204 N  N   . ILE   C 1 52  ? -4.370  -12.927 4.908   1.000 53.572  0  162 ILE   B N   1 ? 
ATOM   2205 C  CA  . ILE   C 1 52  ? -3.802  -12.272 6.082   1.000 48.784  0  162 ILE   B CA  1 ? 
ATOM   2206 C  C   . ILE   C 1 52  ? -2.357  -12.735 6.250   1.000 41.023  0  162 ILE   B C   1 ? 
ATOM   2207 O  O   . ILE   C 1 52  ? -1.985  -13.808 5.778   1.000 38.352  0  162 ILE   B O   1 ? 
ATOM   2208 C  CB  . ILE   C 1 52  ? -4.641  -12.547 7.347   1.000 52.295  0  162 ILE   B CB  1 ? 
ATOM   2209 C  CG1 . ILE   C 1 52  ? -4.543  -14.019 7.792   1.000 43.106  0  162 ILE   B CG1 1 ? 
ATOM   2210 C  CG2 . ILE   C 1 52  ? -6.093  -12.101 7.144   1.000 59.621  0  162 ILE   B CG2 1 ? 
ATOM   2211 C  CD1 . ILE   C 1 52  ? -5.338  -14.345 9.044   1.000 48.521  0  162 ILE   B CD1 1 ? 
ATOM   2212 N  N   . GLU   C 1 53  ? -1.557  -11.914 6.939   1.000 39.347  0  163 GLU   B N   1 ? 
ATOM   2213 C  CA  . GLU   C 1 53  ? -0.185  -12.270 7.269   1.000 43.894  0  163 GLU   B CA  1 ? 
ATOM   2214 C  C   . GLU   C 1 53  ? -0.201  -13.449 8.244   1.000 49.569  0  163 GLU   B C   1 ? 
ATOM   2215 O  O   . GLU   C 1 53  ? -1.173  -13.644 8.974   1.000 45.432  0  163 GLU   B O   1 ? 
ATOM   2216 C  CB  . GLU   C 1 53  ? 0.576   -11.047 7.792   1.000 51.819  0  163 GLU   B CB  1 ? 
ATOM   2217 C  CG  . GLU   C 1 53  ? -0.033  -10.416 9.043   1.000 65.639  0  163 GLU   B CG  1 ? 
ATOM   2218 C  CD  . GLU   C 1 53  ? 0.437   -8.991  9.299   1.000 75.293  0  163 GLU   B CD  1 ? 
ATOM   2219 O  OE1 . GLU   C 1 53  ? 1.650   -8.794  9.526   1.000 65.257  0  163 GLU   B OE1 1 ? 
ATOM   2220 O  OE2 . GLU   C 1 53  ? -0.411  -8.072  9.227   1.000 83.006  0  163 GLU   B OE2 1 ? 
ATOM   2221 N  N   . ASP   C 1 54  ? 0.880   -14.248 8.220   1.000 53.750  0  164 ASP   B N   1 ? 
ATOM   2222 C  CA  . ASP   C 1 54  ? 0.916   -15.530 8.918   1.000 54.146  0  164 ASP   B CA  1 ? 
ATOM   2223 C  C   . ASP   C 1 54  ? 0.971   -15.327 10.430  1.000 47.147  0  164 ASP   B C   1 ? 
ATOM   2224 O  O   . ASP   C 1 54  ? 0.525   -16.194 11.182  1.000 42.034  0  164 ASP   B O   1 ? 
ATOM   2225 C  CB  . ASP   C 1 54  ? 2.061   -16.401 8.435   1.000 52.731  0  164 ASP   B CB  1 ? 
ATOM   2226 C  CG  . ASP   C 1 54  ? 1.858   -17.034 7.069   1.000 66.013  0  164 ASP   B CG  1 ? 
ATOM   2227 O  OD1 . ASP   C 1 54  ? 0.788   -17.649 6.860   1.000 69.776  0  164 ASP   B OD1 1 ? 
ATOM   2228 O  OD2 . ASP   C 1 54  ? 2.788   -16.959 6.250   1.000 76.644  0  164 ASP   B OD2 1 ? 
ATOM   2229 N  N   . SER   C 1 55  ? 1.553   -14.201 10.869  1.000 37.200  0  165 SER   B N   1 ? 
ATOM   2230 C  CA  . SER   C 1 55  ? 1.601   -13.874 12.286  1.000 41.789  0  165 SER   B CA  1 ? 
ATOM   2231 C  C   . SER   C 1 55  ? 0.178   -13.825 12.861  1.000 45.714  0  165 SER   B C   1 ? 
ATOM   2232 O  O   . SER   C 1 55  ? -0.044  -14.223 14.001  1.000 43.890  0  165 SER   B O   1 ? 
ATOM   2233 C  CB  . SER   C 1 55  ? 2.335   -12.581 12.525  1.000 40.946  0  165 SER   B CB  1 ? 
ATOM   2234 O  OG  . SER   C 1 55  ? 1.663   -11.489 11.920  1.000 49.269  0  165 SER   B OG  1 ? 
ATOM   2235 N  N   . LYS   C 1 56  ? -0.785  -13.361 12.039  1.000 43.319  0  166 LYS   B N   1 ? 
ATOM   2236 C  CA  . LYS   C 1 56  ? -2.184  -13.278 12.448  1.000 42.933  0  166 LYS   B CA  1 ? 
ATOM   2237 C  C   . LYS   C 1 56  ? -2.856  -14.650 12.329  1.000 37.183  0  166 LYS   B C   1 ? 
ATOM   2238 O  O   . LYS   C 1 56  ? -3.733  -14.980 13.126  1.000 40.049  0  166 LYS   B O   1 ? 
ATOM   2239 C  CB  . LYS   C 1 56  ? -2.936  -12.216 11.642  1.000 41.423  0  166 LYS   B CB  1 ? 
ATOM   2240 C  CG  . LYS   C 1 56  ? -2.670  -10.782 12.079  1.000 45.826  0  166 LYS   B CG  1 ? 
ATOM   2241 C  CD  . LYS   C 1 56  ? -3.555  -9.750  11.390  1.000 54.588  0  166 LYS   B CD  1 ? 
ATOM   2242 C  CE  . LYS   C 1 56  ? -3.404  -8.382  11.971  1.000 53.419  0  166 LYS   B CE  1 ? 
ATOM   2243 N  NZ  . LYS   C 1 56  ? -4.321  -7.432  11.339  1.000 58.798  0  166 LYS   B NZ  1 ? 
ATOM   2244 N  N   . LEU   C 1 57  ? -2.460  -15.430 11.314  1.000 33.388  0  167 LEU   B N   1 ? 
ATOM   2245 C  CA  . LEU   C 1 57  ? -2.988  -16.777 11.129  1.000 36.500  0  167 LEU   B CA  1 ? 
ATOM   2246 C  C   . LEU   C 1 57  ? -2.506  -17.674 12.271  1.000 35.452  0  167 LEU   B C   1 ? 
ATOM   2247 O  O   . LEU   C 1 57  ? -3.195  -18.616 12.654  1.000 31.401  0  167 LEU   B O   1 ? 
ATOM   2248 C  CB  . LEU   C 1 57  ? -2.570  -17.337 9.770   1.000 40.057  0  167 LEU   B CB  1 ? 
ATOM   2249 C  CG  . LEU   C 1 57  ? -3.091  -18.740 9.433   1.000 44.464  0  167 LEU   B CG  1 ? 
ATOM   2250 C  CD1 . LEU   C 1 57  ? -4.611  -18.752 9.310   1.000 42.641  0  167 LEU   B CD1 1 ? 
ATOM   2251 C  CD2 . LEU   C 1 57  ? -2.447  -19.267 8.164   1.000 44.742  0  167 LEU   B CD2 1 ? 
ATOM   2252 N  N   . ARG   C 1 58  ? -1.296  -17.389 12.777  1.000 36.732  0  168 ARG   B N   1 ? 
ATOM   2253 C  CA  . ARG   C 1 58  ? -0.742  -18.105 13.917  1.000 37.349  0  168 ARG   B CA  1 ? 
ATOM   2254 C  C   . ARG   C 1 58  ? -1.520  -17.730 15.179  1.000 31.058  0  168 ARG   B C   1 ? 
ATOM   2255 O  O   . ARG   C 1 58  ? -1.804  -18.588 16.013  1.000 29.097  0  168 ARG   B O   1 ? 
ATOM   2256 C  CB  . ARG   C 1 58  ? 0.752   -17.789 14.090  1.000 39.907  0  168 ARG   B CB  1 ? 
ATOM   2257 C  CG  . ARG   C 1 58  ? 1.416   -18.505 15.261  1.000 39.337  0  168 ARG   B CG  1 ? 
ATOM   2258 C  CD  . ARG   C 1 58  ? 1.484   -20.015 15.050  1.000 41.300  0  168 ARG   B CD  1 ? 
ATOM   2259 N  NE  . ARG   C 1 58  ? 1.835   -20.751 16.273  1.000 44.588  0  168 ARG   B NE  1 ? 
ATOM   2260 C  CZ  . ARG   C 1 58  ? 1.052   -20.888 17.352  1.000 44.665  0  168 ARG   B CZ  1 ? 
ATOM   2261 N  NH1 . ARG   C 1 58  ? -0.152  -20.335 17.386  1.000 44.652  0  168 ARG   B NH1 1 ? 
ATOM   2262 N  NH2 . ARG   C 1 58  ? 1.475   -21.591 18.385  1.000 44.644  0  168 ARG   B NH2 1 ? 
ATOM   2263 N  N   . ALA   C 1 59  ? -1.826  -16.431 15.320  1.000 30.282  0  169 ALA   B N   1 ? 
ATOM   2264 C  CA  . ALA   C 1 59  ? -2.583  -15.927 16.461  1.000 31.859  0  169 ALA   B CA  1 ? 
ATOM   2265 C  C   . ALA   C 1 59  ? -4.006  -16.495 16.449  1.000 31.564  0  169 ALA   B C   1 ? 
ATOM   2266 O  O   . ALA   C 1 59  ? -4.604  -16.691 17.502  1.000 32.417  0  169 ALA   B O   1 ? 
ATOM   2267 C  CB  . ALA   C 1 59  ? -2.595  -14.417 16.443  1.000 30.417  0  169 ALA   B CB  1 ? 
ATOM   2268 N  N   . LEU   C 1 60  ? -4.552  -16.713 15.244  1.000 30.919  0  170 LEU   B N   1 ? 
ATOM   2269 C  CA  . LEU   C 1 60  ? -5.897  -17.251 15.097  1.000 32.856  0  170 LEU   B CA  1 ? 
ATOM   2270 C  C   . LEU   C 1 60  ? -5.931  -18.709 15.557  1.000 31.188  0  170 LEU   B C   1 ? 
ATOM   2271 O  O   . LEU   C 1 60  ? -6.935  -19.161 16.104  1.000 31.646  0  170 LEU   B O   1 ? 
ATOM   2272 C  CB  . LEU   C 1 60  ? -6.379  -17.098 13.656  1.000 35.303  0  170 LEU   B CB  1 ? 
ATOM   2273 C  CG  . LEU   C 1 60  ? -6.968  -15.732 13.291  1.000 36.328  0  170 LEU   B CG  1 ? 
ATOM   2274 C  CD1 . LEU   C 1 60  ? -7.124  -15.584 11.789  1.000 36.890  0  170 LEU   B CD1 1 ? 
ATOM   2275 C  CD2 . LEU   C 1 60  ? -8.305  -15.530 13.984  1.000 32.659  0  170 LEU   B CD2 1 ? 
ATOM   2276 N  N   . LEU   C 1 61  ? -4.826  -19.434 15.343  1.000 31.918  0  171 LEU   B N   1 ? 
ATOM   2277 C  CA  . LEU   C 1 61  ? -4.718  -20.813 15.806  1.000 36.953  0  171 LEU   B CA  1 ? 
ATOM   2278 C  C   . LEU   C 1 61  ? -4.740  -20.832 17.338  1.000 39.587  0  171 LEU   B C   1 ? 
ATOM   2279 O  O   . LEU   C 1 61  ? -5.379  -21.694 17.939  1.000 47.054  0  171 LEU   B O   1 ? 
ATOM   2280 C  CB  . LEU   C 1 61  ? -3.455  -21.475 15.249  1.000 37.445  0  171 LEU   B CB  1 ? 
ATOM   2281 C  CG  . LEU   C 1 61  ? -3.224  -22.937 15.652  1.000 38.047  0  171 LEU   B CG  1 ? 
ATOM   2282 C  CD1 . LEU   C 1 61  ? -4.395  -23.824 15.250  1.000 41.326  0  171 LEU   B CD1 1 ? 
ATOM   2283 C  CD2 . LEU   C 1 61  ? -1.930  -23.459 15.049  1.000 37.537  0  171 LEU   B CD2 1 ? 
ATOM   2284 N  N   . THR   C 1 62  ? -4.044  -19.861 17.956  1.000 33.971  0  172 THR   B N   1 ? 
ATOM   2285 C  CA  . THR   C 1 62  ? -4.061  -19.697 19.405  1.000 39.735  0  172 THR   B CA  1 ? 
ATOM   2286 C  C   . THR   C 1 62  ? -5.491  -19.389 19.861  1.000 32.401  0  172 THR   B C   1 ? 
ATOM   2287 O  O   . THR   C 1 62  ? -5.955  -19.938 20.853  1.000 29.983  0  172 THR   B O   1 ? 
ATOM   2288 C  CB  . THR   C 1 62  ? -3.089  -18.588 19.823  1.000 41.273  0  172 THR   B CB  1 ? 
ATOM   2289 O  OG1 . THR   C 1 62  ? -1.814  -18.968 19.321  1.000 48.651  0  172 THR   B OG1 1 ? 
ATOM   2290 C  CG2 . THR   C 1 62  ? -3.009  -18.415 21.329  1.000 43.181  0  172 THR   B CG2 1 ? 
ATOM   2291 N  N   . LEU   C 1 63  ? -6.170  -18.490 19.129  1.000 32.213  0  173 LEU   B N   1 ? 
ATOM   2292 C  CA  . LEU   C 1 63  ? -7.545  -18.118 19.441  1.000 36.040  0  173 LEU   B CA  1 ? 
ATOM   2293 C  C   . LEU   C 1 63  ? -8.418  -19.373 19.475  1.000 35.621  0  173 LEU   B C   1 ? 
ATOM   2294 O  O   . LEU   C 1 63  ? -9.215  -19.549 20.394  1.000 28.915  0  173 LEU   B O   1 ? 
ATOM   2295 C  CB  . LEU   C 1 63  ? -8.067  -17.097 18.427  1.000 35.405  0  173 LEU   B CB  1 ? 
ATOM   2296 C  CG  . LEU   C 1 63  ? -9.541  -16.689 18.570  1.000 38.254  0  173 LEU   B CG  1 ? 
ATOM   2297 C  CD1 . LEU   C 1 63  ? -9.827  -16.066 19.925  1.000 37.871  0  173 LEU   B CD1 1 ? 
ATOM   2298 C  CD2 . LEU   C 1 63  ? -9.944  -15.742 17.456  1.000 40.475  0  173 LEU   B CD2 1 ? 
ATOM   2299 N  N   . CYS   C 1 64  ? -8.237  -20.246 18.474  1.000 33.934  0  174 CYS   B N   1 ? 
ATOM   2300 C  CA  . CYS   C 1 64  ? -8.991  -21.485 18.382  1.000 36.482  0  174 CYS   B CA  1 ? 
ATOM   2301 C  C   . CYS   C 1 64  ? -8.662  -22.393 19.566  1.000 36.461  0  174 CYS   B C   1 ? 
ATOM   2302 O  O   . CYS   C 1 64  ? -9.558  -23.002 20.144  1.000 37.313  0  174 CYS   B O   1 ? 
ATOM   2303 C  CB  . CYS   C 1 64  ? -8.717  -22.200 17.066  1.000 41.715  0  174 CYS   B CB  1 ? 
ATOM   2304 S  SG  . CYS   C 1 64  ? -9.263  -21.262 15.617  1.000 50.623  0  174 CYS   B SG  1 ? 
ATOM   2305 N  N   . ALA   C 1 65  ? -7.367  -22.472 19.911  1.000 33.706  0  175 ALA   B N   1 ? 
ATOM   2306 C  CA  . ALA   C 1 65  ? -6.903  -23.314 21.006  1.000 36.475  0  175 ALA   B CA  1 ? 
ATOM   2307 C  C   . ALA   C 1 65  ? -7.494  -22.834 22.333  1.000 36.351  0  175 ALA   B C   1 ? 
ATOM   2308 O  O   . ALA   C 1 65  ? -7.973  -23.641 23.131  1.000 37.331  0  175 ALA   B O   1 ? 
ATOM   2309 C  CB  . ALA   C 1 65  ? -5.388  -23.320 21.048  1.000 36.257  0  175 ALA   B CB  1 ? 
ATOM   2310 N  N   . VAL   C 1 66  ? -7.441  -21.515 22.557  1.000 34.574  0  176 VAL   B N   1 ? 
ATOM   2311 C  CA  . VAL   C 1 66  ? -7.933  -20.915 23.789  1.000 38.254  0  176 VAL   B CA  1 ? 
ATOM   2312 C  C   . VAL   C 1 66  ? -9.453  -21.086 23.861  1.000 38.562  0  176 VAL   B C   1 ? 
ATOM   2313 O  O   . VAL   C 1 66  ? -9.982  -21.463 24.901  1.000 39.479  0  176 VAL   B O   1 ? 
ATOM   2314 C  CB  . VAL   C 1 66  ? -7.521  -19.429 23.888  1.000 37.818  0  176 VAL   B CB  1 ? 
ATOM   2315 C  CG1 . VAL   C 1 66  ? -8.258  -18.697 25.004  1.000 39.444  0  176 VAL   B CG1 1 ? 
ATOM   2316 C  CG2 . VAL   C 1 66  ? -6.018  -19.273 24.058  1.000 37.070  0  176 VAL   B CG2 1 ? 
ATOM   2317 N  N   . MET   C 1 67  ? -10.142 -20.793 22.746  1.000 47.022  0  177 MET   B N   1 ? 
ATOM   2318 C  CA  . MET   C 1 67  ? -11.599 -20.902 22.678  1.000 42.467  0  177 MET   B CA  1 ? 
ATOM   2319 C  C   . MET   C 1 67  ? -12.037 -22.348 22.951  1.000 39.009  0  177 MET   B C   1 ? 
ATOM   2320 O  O   . MET   C 1 67  ? -13.074 -22.575 23.565  1.000 33.238  0  177 MET   B O   1 ? 
ATOM   2321 C  CB  . MET   C 1 67  ? -12.124 -20.463 21.303  1.000 46.938  0  177 MET   B CB  1 ? 
ATOM   2322 C  CG  . MET   C 1 67  ? -12.166 -18.953 21.099  1.000 60.757  0  177 MET   B CG  1 ? 
ATOM   2323 S  SD  . MET   C 1 67  ? -13.466 -18.139 22.052  1.000 82.209  0  177 MET   B SD  1 ? 
ATOM   2324 C  CE  . MET   C 1 67  ? -14.950 -18.774 21.259  1.000 79.529  0  177 MET   B CE  1 ? 
ATOM   2325 N  N   . THR   C 1 68  ? -11.243 -23.318 22.472  1.000 30.838  0  178 THR   B N   1 ? 
ATOM   2326 C  CA  . THR   C 1 68  ? -11.562 -24.727 22.649  1.000 33.090  0  178 THR   B CA  1 ? 
ATOM   2327 C  C   . THR   C 1 68  ? -11.588 -25.064 24.143  1.000 34.070  0  178 THR   B C   1 ? 
ATOM   2328 O  O   . THR   C 1 68  ? -12.450 -25.816 24.592  1.000 32.470  0  178 THR   B O   1 ? 
ATOM   2329 C  CB  . THR   C 1 68  ? -10.551 -25.590 21.892  1.000 36.843  0  178 THR   B CB  1 ? 
ATOM   2330 O  OG1 . THR   C 1 68  ? -10.686 -25.226 20.523  1.000 40.766  0  178 THR   B OG1 1 ? 
ATOM   2331 C  CG2 . THR   C 1 68  ? -10.817 -27.076 22.047  1.000 40.094  0  178 THR   B CG2 1 ? 
ATOM   2332 N  N   . ARG   C 1 69  ? -10.669 -24.454 24.912  1.000 34.431  0  179 ARG   B N   1 ? 
ATOM   2333 C  CA  . ARG   C 1 69  ? -10.524 -24.756 26.330  1.000 32.604  0  179 ARG   B CA  1 ? 
ATOM   2334 C  C   . ARG   C 1 69  ? -11.606 -24.044 27.157  1.000 35.536  0  179 ARG   B C   1 ? 
ATOM   2335 O  O   . ARG   C 1 69  ? -11.656 -24.210 28.374  1.000 41.214  0  179 ARG   B O   1 ? 
ATOM   2336 C  CB  . ARG   C 1 69  ? -9.107  -24.420 26.810  1.000 31.098  0  179 ARG   B CB  1 ? 
ATOM   2337 C  CG  . ARG   C 1 69  ? -8.056  -25.402 26.303  1.000 31.138  0  179 ARG   B CG  1 ? 
ATOM   2338 C  CD  . ARG   C 1 69  ? -6.707  -25.229 26.989  1.000 30.611  0  179 ARG   B CD  1 ? 
ATOM   2339 N  NE  . ARG   C 1 69  ? -5.989  -24.027 26.550  1.000 32.118  0  179 ARG   B NE  1 ? 
ATOM   2340 C  CZ  . ARG   C 1 69  ? -5.341  -23.887 25.396  1.000 32.112  0  179 ARG   B CZ  1 ? 
ATOM   2341 N  NH1 . ARG   C 1 69  ? -5.220  -24.909 24.563  1.000 35.692  0  179 ARG   B NH1 1 ? 
ATOM   2342 N  NH2 . ARG   C 1 69  ? -4.755  -22.735 25.109  1.000 32.677  0  179 ARG   B NH2 1 ? 
ATOM   2343 N  N   . LYS   C 1 70  ? -12.493 -23.289 26.483  1.000 35.825  0  180 LYS   B N   1 ? 
ATOM   2344 C  CA  . LYS   C 1 70  ? -13.644 -22.683 27.142  1.000 35.034  0  180 LYS   B CA  1 ? 
ATOM   2345 C  C   . LYS   C 1 70  ? -14.861 -23.610 27.023  1.000 35.846  0  180 LYS   B C   1 ? 
ATOM   2346 O  O   . LYS   C 1 70  ? -15.951 -23.261 27.473  1.000 33.311  0  180 LYS   B O   1 ? 
ATOM   2347 C  CB  . LYS   C 1 70  ? -13.956 -21.301 26.557  1.000 36.249  0  180 LYS   B CB  1 ? 
ATOM   2348 C  CG  . LYS   C 1 70  ? -12.784 -20.325 26.518  1.000 41.069  0  180 LYS   B CG  1 ? 
ATOM   2349 C  CD  . LYS   C 1 70  ? -12.013 -20.180 27.830  1.000 38.831  0  180 LYS   B CD  1 ? 
ATOM   2350 C  CE  . LYS   C 1 70  ? -10.831 -19.263 27.687  1.000 38.036  0  180 LYS   B CE  1 ? 
ATOM   2351 N  NZ  . LYS   C 1 70  ? -9.967  -19.285 28.870  1.000 40.073  0  180 LYS   B NZ  1 ? 
ATOM   2352 N  N   . PHE   C 1 71  ? -14.668 -24.776 26.387  1.000 38.130  0  181 PHE   B N   1 ? 
ATOM   2353 C  CA  . PHE   C 1 71  ? -15.703 -25.799 26.314  1.000 43.098  0  181 PHE   B CA  1 ? 
ATOM   2354 C  C   . PHE   C 1 71  ? -15.395 -26.887 27.336  1.000 37.396  0  181 PHE   B C   1 ? 
ATOM   2355 O  O   . PHE   C 1 71  ? -14.240 -27.252 27.522  1.000 33.681  0  181 PHE   B O   1 ? 
ATOM   2356 C  CB  . PHE   C 1 71  ? -15.786 -26.420 24.913  1.000 42.261  0  181 PHE   B CB  1 ? 
ATOM   2357 C  CG  . PHE   C 1 71  ? -16.419 -25.541 23.847  1.000 45.951  0  181 PHE   B CG  1 ? 
ATOM   2358 C  CD1 . PHE   C 1 71  ? -15.649 -24.644 23.107  1.000 45.877  0  181 PHE   B CD1 1 ? 
ATOM   2359 C  CD2 . PHE   C 1 71  ? -17.777 -25.654 23.543  1.000 44.800  0  181 PHE   B CD2 1 ? 
ATOM   2360 C  CE1 . PHE   C 1 71  ? -16.231 -23.853 22.126  1.000 45.657  0  181 PHE   B CE1 1 ? 
ATOM   2361 C  CE2 . PHE   C 1 71  ? -18.352 -24.862 22.560  1.000 42.765  0  181 PHE   B CE2 1 ? 
ATOM   2362 C  CZ  . PHE   C 1 71  ? -17.581 -23.963 21.856  1.000 50.708  0  181 PHE   B CZ  1 ? 
ATOM   2363 N  N   . SER   C 1 72  ? -16.448 -27.420 27.972  1.000 35.463  0  182 SER   B N   1 ? 
ATOM   2364 C  CA  . SER   C 1 72  ? -16.322 -28.619 28.785  1.000 39.698  0  182 SER   B CA  1 ? 
ATOM   2365 C  C   . SER   C 1 72  ? -15.912 -29.790 27.888  1.000 39.610  0  182 SER   B C   1 ? 
ATOM   2366 O  O   . SER   C 1 72  ? -16.242 -29.812 26.701  1.000 41.305  0  182 SER   B O   1 ? 
ATOM   2367 C  CB  . SER   C 1 72  ? -17.603 -28.916 29.535  1.000 39.619  0  182 SER   B CB  1 ? 
ATOM   2368 O  OG  . SER   C 1 72  ? -18.690 -29.101 28.637  1.000 44.606  0  182 SER   B OG  1 ? 
ATOM   2369 N  N   . LYS   C 1 73  ? -15.218 -30.772 28.475  1.000 44.741  0  183 LYS   B N   1 ? 
ATOM   2370 C  CA  . LYS   C 1 73  ? -14.647 -31.877 27.716  1.000 51.731  0  183 LYS   B CA  1 ? 
ATOM   2371 C  C   . LYS   C 1 73  ? -15.763 -32.704 27.065  1.000 45.442  0  183 LYS   B C   1 ? 
ATOM   2372 O  O   . LYS   C 1 73  ? -15.548 -33.328 26.028  1.000 44.895  0  183 LYS   B O   1 ? 
ATOM   2373 C  CB  . LYS   C 1 73  ? -13.764 -32.746 28.619  1.000 59.836  0  183 LYS   B CB  1 ? 
ATOM   2374 C  CG  . LYS   C 1 73  ? -12.781 -33.641 27.874  1.000 70.278  0  183 LYS   B CG  1 ? 
ATOM   2375 C  CD  . LYS   C 1 73  ? -11.746 -34.316 28.770  1.000 77.832  0  183 LYS   B CD  1 ? 
ATOM   2376 C  CE  . LYS   C 1 73  ? -10.592 -34.894 27.998  1.000 88.036  0  183 LYS   B CE  1 ? 
ATOM   2377 N  NZ  . LYS   C 1 73  ? -9.759  -33.851 27.381  1.000 99.851  0  183 LYS   B NZ  1 ? 
ATOM   2378 N  N   . SER   C 1 74  ? -16.966 -32.647 27.654  1.000 42.161  0  184 SER   B N   1 ? 
ATOM   2379 C  CA  . SER   C 1 74  ? -18.107 -33.417 27.178  1.000 48.287  0  184 SER   B CA  1 ? 
ATOM   2380 C  C   . SER   C 1 74  ? -18.625 -32.884 25.832  1.000 45.643  0  184 SER   B C   1 ? 
ATOM   2381 O  O   . SER   C 1 74  ? -19.344 -33.591 25.129  1.000 50.338  0  184 SER   B O   1 ? 
ATOM   2382 C  CB  . SER   C 1 74  ? -19.204 -33.425 28.209  1.000 53.824  0  184 SER   B CB  1 ? 
ATOM   2383 O  OG  . SER   C 1 74  ? -19.564 -32.099 28.574  1.000 56.240  0  184 SER   B OG  1 ? 
ATOM   2384 N  N   . GLN   C 1 75  ? -18.248 -31.641 25.478  1.000 47.265  0  185 GLN   B N   1 ? 
ATOM   2385 C  CA  . GLN   C 1 75  ? -18.784 -30.978 24.290  1.000 40.718  0  185 GLN   B CA  1 ? 
ATOM   2386 C  C   . GLN   C 1 75  ? -17.865 -31.178 23.079  1.000 41.591  0  185 GLN   B C   1 ? 
ATOM   2387 O  O   . GLN   C 1 75  ? -18.221 -30.785 21.970  1.000 46.554  0  185 GLN   B O   1 ? 
ATOM   2388 C  CB  . GLN   C 1 75  ? -18.986 -29.483 24.554  1.000 39.056  0  185 GLN   B CB  1 ? 
ATOM   2389 C  CG  . GLN   C 1 75  ? -20.208 -29.156 25.406  1.000 41.184  0  185 GLN   B CG  1 ? 
ATOM   2390 C  CD  . GLN   C 1 75  ? -21.517 -29.499 24.723  1.000 49.520  0  185 GLN   B CD  1 ? 
ATOM   2391 O  OE1 . GLN   C 1 75  ? -21.904 -30.668 24.617  1.000 52.951  0  185 GLN   B OE1 1 ? 
ATOM   2392 N  NE2 . GLN   C 1 75  ? -22.228 -28.474 24.280  1.000 49.058  0  185 GLN   B NE2 1 ? 
ATOM   2393 N  N   . LEU   C 1 76  ? -16.705 -31.819 23.289  1.000 40.277  0  186 LEU   B N   1 ? 
ATOM   2394 C  CA  . LEU   C 1 76  ? -15.717 -31.982 22.227  1.000 42.642  0  186 LEU   B CA  1 ? 
ATOM   2395 C  C   . LEU   C 1 76  ? -16.296 -32.825 21.088  1.000 39.074  0  186 LEU   B C   1 ? 
ATOM   2396 O  O   . LEU   C 1 76  ? -16.060 -32.532 19.919  1.000 41.669  0  186 LEU   B O   1 ? 
ATOM   2397 C  CB  . LEU   C 1 76  ? -14.437 -32.602 22.785  1.000 44.387  0  186 LEU   B CB  1 ? 
ATOM   2398 C  CG  . LEU   C 1 76  ? -13.668 -31.756 23.806  1.000 48.619  0  186 LEU   B CG  1 ? 
ATOM   2399 C  CD1 . LEU   C 1 76  ? -12.497 -32.543 24.362  1.000 49.268  0  186 LEU   B CD1 1 ? 
ATOM   2400 C  CD2 . LEU   C 1 76  ? -13.188 -30.436 23.204  1.000 50.213  0  186 LEU   B CD2 1 ? 
ATOM   2401 N  N   . SER   C 1 77  ? -17.044 -33.875 21.443  1.000 37.612  0  187 SER   B N   1 ? 
ATOM   2402 C  CA  . SER   C 1 77  ? -17.611 -34.787 20.459  1.000 43.374  0  187 SER   B CA  1 ? 
ATOM   2403 C  C   . SER   C 1 77  ? -18.643 -34.063 19.586  1.000 37.278  0  187 SER   B C   1 ? 
ATOM   2404 O  O   . SER   C 1 77  ? -18.701 -34.295 18.383  1.000 39.209  0  187 SER   B O   1 ? 
ATOM   2405 C  CB  . SER   C 1 77  ? -18.208 -36.004 21.126  1.000 49.296  0  187 SER   B CB  1 ? 
ATOM   2406 O  OG  . SER   C 1 77  ? -19.159 -35.631 22.112  1.000 73.693  0  187 SER   B OG  1 ? 
ATOM   2407 N  N   . LEU   C 1 78  ? -19.462 -33.197 20.208  1.000 39.077  0  188 LEU   B N   1 ? 
ATOM   2408 C  CA  . LEU   C 1 78  ? -20.461 -32.419 19.481  1.000 41.463  0  188 LEU   B CA  1 ? 
ATOM   2409 C  C   . LEU   C 1 78  ? -19.758 -31.428 18.556  1.000 42.446  0  188 LEU   B C   1 ? 
ATOM   2410 O  O   . LEU   C 1 78  ? -20.178 -31.230 17.416  1.000 45.388  0  188 LEU   B O   1 ? 
ATOM   2411 C  CB  . LEU   C 1 78  ? -21.403 -31.697 20.445  1.000 43.766  0  188 LEU   B CB  1 ? 
ATOM   2412 C  CG  . LEU   C 1 78  ? -22.374 -30.688 19.808  1.000 44.116  0  188 LEU   B CG  1 ? 
ATOM   2413 C  CD1 . LEU   C 1 78  ? -23.210 -31.331 18.710  1.000 46.478  0  188 LEU   B CD1 1 ? 
ATOM   2414 C  CD2 . LEU   C 1 78  ? -23.276 -30.064 20.857  1.000 40.261  0  188 LEU   B CD2 1 ? 
ATOM   2415 N  N   . LEU   C 1 79  ? -18.712 -30.786 19.078  1.000 37.199  0  189 LEU   B N   1 ? 
ATOM   2416 C  CA  . LEU   C 1 79  ? -17.947 -29.809 18.322  1.000 39.246  0  189 LEU   B CA  1 ? 
ATOM   2417 C  C   . LEU   C 1 79  ? -17.376 -30.468 17.063  1.000 38.461  0  189 LEU   B C   1 ? 
ATOM   2418 O  O   . LEU   C 1 79  ? -17.448 -29.899 15.979  1.000 41.570  0  189 LEU   B O   1 ? 
ATOM   2419 C  CB  . LEU   C 1 79  ? -16.852 -29.244 19.233  1.000 46.763  0  189 LEU   B CB  1 ? 
ATOM   2420 C  CG  . LEU   C 1 79  ? -15.995 -28.110 18.662  1.000 51.715  0  189 LEU   B CG  1 ? 
ATOM   2421 C  CD1 . LEU   C 1 79  ? -16.833 -26.959 18.127  1.000 50.846  0  189 LEU   B CD1 1 ? 
ATOM   2422 C  CD2 . LEU   C 1 79  ? -15.045 -27.617 19.734  1.000 54.910  0  189 LEU   B CD2 1 ? 
ATOM   2423 N  N   . CYS   C 1 80  ? -16.860 -31.699 17.220  1.000 44.086  0  190 CYS   B N   1 ? 
ATOM   2424 C  CA  . CYS   C 1 80  ? -16.293 -32.459 16.111  1.000 49.113  0  190 CYS   B CA  1 ? 
ATOM   2425 C  C   . CYS   C 1 80  ? -17.373 -32.798 15.080  1.000 47.190  0  190 CYS   B C   1 ? 
ATOM   2426 O  O   . CYS   C 1 80  ? -17.160 -32.639 13.882  1.000 49.018  0  190 CYS   B O   1 ? 
ATOM   2427 C  CB  . CYS   C 1 80  ? -15.636 -33.742 16.601  1.000 51.186  0  190 CYS   B CB  1 ? 
ATOM   2428 S  SG  . CYS   C 1 80  ? -15.230 -34.894 15.265  1.000 51.651  0  190 CYS   B SG  1 ? 
ATOM   2429 N  N   . GLU   C 1 81  ? -18.507 -33.319 15.561  1.000 47.449  0  191 GLU   B N   1 ? 
ATOM   2430 C  CA  . GLU   C 1 81  ? -19.605 -33.721 14.692  1.000 51.567  0  191 GLU   B CA  1 ? 
ATOM   2431 C  C   . GLU   C 1 81  ? -20.091 -32.515 13.880  1.000 46.789  0  191 GLU   B C   1 ? 
ATOM   2432 O  O   . GLU   C 1 81  ? -20.278 -32.614 12.670  1.000 52.211  0  191 GLU   B O   1 ? 
ATOM   2433 C  CB  . GLU   C 1 81  ? -20.731 -34.340 15.526  1.000 58.044  0  191 GLU   B CB  1 ? 
ATOM   2434 C  CG  . GLU   C 1 81  ? -22.000 -34.650 14.730  1.000 78.738  0  191 GLU   B CG  1 ? 
ATOM   2435 C  CD  . GLU   C 1 81  ? -21.869 -35.741 13.671  1.000 98.365  0  191 GLU   B CD  1 ? 
ATOM   2436 O  OE1 . GLU   C 1 81  ? -21.068 -35.577 12.726  1.000 99.395  0  191 GLU   B OE1 1 ? 
ATOM   2437 O  OE2 . GLU   C 1 81  ? -22.605 -36.745 13.777  1.000 111.843 0  191 GLU   B OE2 1 ? 
ATOM   2438 N  N   . THR   C 1 82  ? -20.286 -31.378 14.561  1.000 42.206  0  192 THR   B N   1 ? 
ATOM   2439 C  CA  . THR   C 1 82  ? -20.784 -30.172 13.916  1.000 40.766  0  192 THR   B CA  1 ? 
ATOM   2440 C  C   . THR   C 1 82  ? -19.761 -29.691 12.881  1.000 35.304  0  192 THR   B C   1 ? 
ATOM   2441 O  O   . THR   C 1 82  ? -20.135 -29.219 11.809  1.000 34.069  0  192 THR   B O   1 ? 
ATOM   2442 C  CB  . THR   C 1 82  ? -21.077 -29.101 14.969  1.000 42.278  0  192 THR   B CB  1 ? 
ATOM   2443 O  OG1 . THR   C 1 82  ? -21.812 -29.750 16.005  1.000 40.863  0  192 THR   B OG1 1 ? 
ATOM   2444 C  CG2 . THR   C 1 82  ? -21.893 -27.949 14.413  1.000 42.961  0  192 THR   B CG2 1 ? 
ATOM   2445 N  N   . HIS   C 1 83  ? -18.472 -29.847 13.207  1.000 34.297  0  193 HIS   B N   1 ? 
ATOM   2446 C  CA  . HIS   C 1 83  ? -17.388 -29.469 12.308  1.000 36.655  0  193 HIS   B CA  1 ? 
ATOM   2447 C  C   . HIS   C 1 83  ? -17.484 -30.287 11.017  1.000 37.864  0  193 HIS   B C   1 ? 
ATOM   2448 O  O   . HIS   C 1 83  ? -17.398 -29.735 9.921   1.000 32.973  0  193 HIS   B O   1 ? 
ATOM   2449 C  CB  . HIS   C 1 83  ? -16.030 -29.670 12.996  1.000 35.548  0  193 HIS   B CB  1 ? 
ATOM   2450 C  CG  . HIS   C 1 83  ? -14.854 -29.237 12.183  1.000 40.333  0  193 HIS   B CG  1 ? 
ATOM   2451 N  ND1 . HIS   C 1 83  ? -14.021 -28.209 12.572  1.000 38.227  0  193 HIS   B ND1 1 ? 
ATOM   2452 C  CD2 . HIS   C 1 83  ? -14.277 -29.786 11.104  1.000 43.592  0  193 HIS   B CD2 1 ? 
ATOM   2453 C  CE1 . HIS   C 1 83  ? -13.027 -28.099 11.702  1.000 40.194  0  193 HIS   B CE1 1 ? 
ATOM   2454 N  NE2 . HIS   C 1 83  ? -13.167 -29.039 10.800  1.000 45.538  0  193 HIS   B NE2 1 ? 
ATOM   2455 N  N   . LEU   C 1 84  ? -17.646 -31.611 11.171  1.000 42.721  0  194 LEU   B N   1 ? 
ATOM   2456 C  CA  . LEU   C 1 84  ? -17.711 -32.534 10.042  1.000 42.806  0  194 LEU   B CA  1 ? 
ATOM   2457 C  C   . LEU   C 1 84  ? -18.892 -32.174 9.147   1.000 42.525  0  194 LEU   B C   1 ? 
ATOM   2458 O  O   . LEU   C 1 84  ? -18.747 -32.069 7.933   1.000 42.136  0  194 LEU   B O   1 ? 
ATOM   2459 C  CB  . LEU   C 1 84  ? -17.833 -33.967 10.558  1.000 42.393  0  194 LEU   B CB  1 ? 
ATOM   2460 C  CG  . LEU   C 1 84  ? -16.616 -34.526 11.301  1.000 47.589  0  194 LEU   B CG  1 ? 
ATOM   2461 C  CD1 . LEU   C 1 84  ? -17.011 -35.755 12.098  1.000 49.391  0  194 LEU   B CD1 1 ? 
ATOM   2462 C  CD2 . LEU   C 1 84  ? -15.478 -34.852 10.345  1.000 39.620  0  194 LEU   B CD2 1 ? 
ATOM   2463 N  N   . ARG   C 1 85  ? -20.061 -32.001 9.766   1.000 43.768  0  195 ARG   B N   1 ? 
ATOM   2464 C  CA  . ARG   C 1 85  ? -21.296 -31.781 9.038   1.000 51.689  0  195 ARG   B CA  1 ? 
ATOM   2465 C  C   . ARG   C 1 85  ? -21.189 -30.506 8.196   1.000 56.537  0  195 ARG   B C   1 ? 
ATOM   2466 O  O   . ARG   C 1 85  ? -21.493 -30.532 7.007   1.000 60.010  0  195 ARG   B O   1 ? 
ATOM   2467 C  CB  . ARG   C 1 85  ? -22.477 -31.789 10.020  1.000 54.723  0  195 ARG   B CB  1 ? 
ATOM   2468 C  CG  . ARG   C 1 85  ? -23.831 -31.458 9.406   1.000 66.267  0  195 ARG   B CG  1 ? 
ATOM   2469 C  CD  . ARG   C 1 85  ? -24.976 -32.283 10.014  1.000 80.155  0  195 ARG   B CD  1 ? 
ATOM   2470 N  NE  . ARG   C 1 85  ? -24.855 -32.483 11.467  1.000 92.024  0  195 ARG   B NE  1 ? 
ATOM   2471 C  CZ  . ARG   C 1 85  ? -24.792 -33.679 12.085  1.000 86.120  0  195 ARG   B CZ  1 ? 
ATOM   2472 N  NH1 . ARG   C 1 85  ? -24.853 -34.801 11.385  1.000 84.384  0  195 ARG   B NH1 1 ? 
ATOM   2473 N  NH2 . ARG   C 1 85  ? -24.685 -33.739 13.401  1.000 91.038  0  195 ARG   B NH2 1 ? 
ATOM   2474 N  N   . ARG   C 1 86  ? -20.677 -29.419 8.801   1.000 47.710  0  196 ARG   B N   1 ? 
ATOM   2475 C  CA  . ARG   C 1 86  ? -20.593 -28.126 8.126   1.000 45.694  0  196 ARG   B CA  1 ? 
ATOM   2476 C  C   . ARG   C 1 86  ? -19.642 -28.209 6.924   1.000 44.386  0  196 ARG   B C   1 ? 
ATOM   2477 O  O   . ARG   C 1 86  ? -19.911 -27.623 5.881   1.000 42.443  0  196 ARG   B O   1 ? 
ATOM   2478 C  CB  . ARG   C 1 86  ? -20.114 -27.022 9.079   1.000 50.624  0  196 ARG   B CB  1 ? 
ATOM   2479 C  CG  . ARG   C 1 86  ? -20.223 -25.615 8.498   1.000 59.747  0  196 ARG   B CG  1 ? 
ATOM   2480 C  CD  . ARG   C 1 86  ? -19.348 -24.597 9.228   1.000 66.869  0  196 ARG   B CD  1 ? 
ATOM   2481 N  NE  . ARG   C 1 86  ? -19.500 -23.240 8.683   1.000 69.252  0  196 ARG   B NE  1 ? 
ATOM   2482 C  CZ  . ARG   C 1 86  ? -18.535 -22.521 8.092   1.000 76.484  0  196 ARG   B CZ  1 ? 
ATOM   2483 N  NH1 . ARG   C 1 86  ? -17.327 -23.034 7.911   1.000 78.509  0  196 ARG   B NH1 1 ? 
ATOM   2484 N  NH2 . ARG   C 1 86  ? -18.795 -21.295 7.666   1.000 82.975  0  196 ARG   B NH2 1 ? 
ATOM   2485 N  N   . GLU   C 1 87  ? -18.514 -28.914 7.098   1.000 44.640  0  197 GLU   B N   1 ? 
ATOM   2486 C  CA  . GLU   C 1 87  ? -17.452 -28.931 6.097   1.000 46.651  0  197 GLU   B CA  1 ? 
ATOM   2487 C  C   . GLU   C 1 87  ? -17.695 -30.037 5.064   1.000 46.317  0  197 GLU   B C   1 ? 
ATOM   2488 O  O   . GLU   C 1 87  ? -16.957 -30.137 4.086   1.000 49.697  0  197 GLU   B O   1 ? 
ATOM   2489 C  CB  . GLU   C 1 87  ? -16.088 -29.094 6.767   1.000 43.757  0  197 GLU   B CB  1 ? 
ATOM   2490 C  CG  . GLU   C 1 87  ? -15.712 -27.922 7.672   1.000 48.387  0  197 GLU   B CG  1 ? 
ATOM   2491 C  CD  . GLU   C 1 87  ? -15.690 -26.567 6.980   1.000 52.857  0  197 GLU   B CD  1 ? 
ATOM   2492 O  OE1 . GLU   C 1 87  ? -14.918 -26.412 6.015   1.000 67.578  0  197 GLU   B OE1 1 ? 
ATOM   2493 O  OE2 . GLU   C 1 87  ? -16.443 -25.665 7.411   1.000 61.334  0  197 GLU   B OE2 1 ? 
ATOM   2494 N  N   . GLY   C 1 88  ? -18.718 -30.868 5.296   1.000 50.431  0  198 GLY   B N   1 ? 
ATOM   2495 C  CA  . GLY   C 1 88  ? -19.091 -31.914 4.355   1.000 51.351  0  198 GLY   B CA  1 ? 
ATOM   2496 C  C   . GLY   C 1 88  ? -18.061 -33.042 4.328   1.000 52.658  0  198 GLY   B C   1 ? 
ATOM   2497 O  O   . GLY   C 1 88  ? -17.739 -33.563 3.264   1.000 50.400  0  198 GLY   B O   1 ? 
ATOM   2498 N  N   . LEU   C 1 89  ? -17.569 -33.416 5.519   1.000 56.243  0  199 LEU   B N   1 ? 
ATOM   2499 C  CA  . LEU   C 1 89  ? -16.601 -34.493 5.668   1.000 55.391  0  199 LEU   B CA  1 ? 
ATOM   2500 C  C   . LEU   C 1 89  ? -17.340 -35.781 6.013   1.000 53.504  0  199 LEU   B C   1 ? 
ATOM   2501 O  O   . LEU   C 1 89  ? -18.444 -35.740 6.557   1.000 44.148  0  199 LEU   B O   1 ? 
ATOM   2502 C  CB  . LEU   C 1 89  ? -15.587 -34.117 6.750   1.000 51.350  0  199 LEU   B CB  1 ? 
ATOM   2503 C  CG  . LEU   C 1 89  ? -14.584 -33.018 6.379   1.000 58.104  0  199 LEU   B CG  1 ? 
ATOM   2504 C  CD1 . LEU   C 1 89  ? -14.069 -32.304 7.617   1.000 57.478  0  199 LEU   B CD1 1 ? 
ATOM   2505 C  CD2 . LEU   C 1 89  ? -13.419 -33.596 5.579   1.000 63.819  0  199 LEU   B CD2 1 ? 
ATOM   2506 N  N   . GLY   C 1 90  ? -16.718 -36.923 5.677   1.000 57.858  0  200 GLY   B N   1 ? 
ATOM   2507 C  CA  . GLY   C 1 90  ? -17.273 -38.232 5.989   1.000 66.106  0  200 GLY   B CA  1 ? 
ATOM   2508 C  C   . GLY   C 1 90  ? -16.983 -38.623 7.437   1.000 67.434  0  200 GLY   B C   1 ? 
ATOM   2509 O  O   . GLY   C 1 90  ? -16.296 -37.898 8.154   1.000 64.259  0  200 GLY   B O   1 ? 
ATOM   2510 N  N   . GLN   C 1 91  ? -17.483 -39.802 7.839   1.000 77.559  0  201 GLN   B N   1 ? 
ATOM   2511 C  CA  . GLN   C 1 91  ? -17.306 -40.304 9.197   1.000 80.554  0  201 GLN   B CA  1 ? 
ATOM   2512 C  C   . GLN   C 1 91  ? -15.872 -40.810 9.389   1.000 74.251  0  201 GLN   B C   1 ? 
ATOM   2513 O  O   . GLN   C 1 91  ? -15.419 -40.973 10.519  1.000 80.777  0  201 GLN   B O   1 ? 
ATOM   2514 C  CB  . GLN   C 1 91  ? -18.311 -41.417 9.494   1.000 93.207  0  201 GLN   B CB  1 ? 
ATOM   2515 C  CG  . GLN   C 1 91  ? -19.766 -40.960 9.481   1.000 106.270 0  201 GLN   B CG  1 ? 
ATOM   2516 C  CD  . GLN   C 1 91  ? -20.747 -42.083 9.747   1.000 126.642 0  201 GLN   B CD  1 ? 
ATOM   2517 O  OE1 . GLN   C 1 91  ? -20.365 -43.241 9.952   1.000 141.536 0  201 GLN   B OE1 1 ? 
ATOM   2518 N  NE2 . GLN   C 1 91  ? -22.029 -41.749 9.745   1.000 129.673 0  201 GLN   B NE2 1 ? 
ATOM   2519 N  N   . ASP   C 1 92  ? -15.164 -41.042 8.272   1.000 70.085  0  202 ASP   B N   1 ? 
ATOM   2520 C  CA  . ASP   C 1 92  ? -13.789 -41.524 8.306   1.000 77.727  0  202 ASP   B CA  1 ? 
ATOM   2521 C  C   . ASP   C 1 92  ? -12.855 -40.427 8.835   1.000 74.300  0  202 ASP   B C   1 ? 
ATOM   2522 O  O   . ASP   C 1 92  ? -11.724 -40.714 9.220   1.000 83.245  0  202 ASP   B O   1 ? 
ATOM   2523 C  CB  . ASP   C 1 92  ? -13.347 -42.016 6.934   1.000 80.325  0  202 ASP   B CB  1 ? 
ATOM   2524 C  CG  . ASP   C 1 92  ? -13.332 -40.961 5.835   1.000 84.652  0  202 ASP   B CG  1 ? 
ATOM   2525 O  OD1 . ASP   C 1 92  ? -14.362 -40.275 5.669   1.000 84.203  0  202 ASP   B OD1 1 ? 
ATOM   2526 O  OD2 . ASP   C 1 92  ? -12.304 -40.857 5.136   1.000 91.887  0  202 ASP   B OD2 1 ? 
ATOM   2527 N  N   . GLN   C 1 93  ? -13.340 -39.172 8.839   1.000 73.257  0  203 GLN   B N   1 ? 
ATOM   2528 C  CA  . GLN   C 1 93  ? -12.540 -38.029 9.266   1.000 69.283  0  203 GLN   B CA  1 ? 
ATOM   2529 C  C   . GLN   C 1 93  ? -12.892 -37.630 10.706  1.000 62.864  0  203 GLN   B C   1 ? 
ATOM   2530 O  O   . GLN   C 1 93  ? -12.356 -36.655 11.224  1.000 57.741  0  203 GLN   B O   1 ? 
ATOM   2531 C  CB  . GLN   C 1 93  ? -12.756 -36.865 8.297   1.000 68.028  0  203 GLN   B CB  1 ? 
ATOM   2532 C  CG  . GLN   C 1 93  ? -12.111 -37.069 6.930   1.000 70.674  0  203 GLN   B CG  1 ? 
ATOM   2533 C  CD  . GLN   C 1 93  ? -10.601 -36.950 6.964   1.000 72.189  0  203 GLN   B CD  1 ? 
ATOM   2534 O  OE1 . GLN   C 1 93  ? -10.045 -35.879 7.231   1.000 70.916  0  203 GLN   B OE1 1 ? 
ATOM   2535 N  NE2 . GLN   C 1 93  ? -9.919  -38.049 6.675   1.000 80.781  0  203 GLN   B NE2 1 ? 
ATOM   2536 N  N   . ALA   C 1 94  ? -13.753 -38.421 11.361  1.000 53.576  0  204 ALA   B N   1 ? 
ATOM   2537 C  CA  . ALA   C 1 94  ? -14.158 -38.148 12.732  1.000 53.573  0  204 ALA   B CA  1 ? 
ATOM   2538 C  C   . ALA   C 1 94  ? -12.975 -38.346 13.681  1.000 61.330  0  204 ALA   B C   1 ? 
ATOM   2539 O  O   . ALA   C 1 94  ? -12.752 -37.534 14.578  1.000 60.630  0  204 ALA   B O   1 ? 
ATOM   2540 C  CB  . ALA   C 1 94  ? -15.321 -39.038 13.113  1.000 56.686  0  204 ALA   B CB  1 ? 
ATOM   2541 N  N   . GLU   C 1 95  ? -12.226 -39.436 13.467  1.000 63.995  0  205 GLU   B N   1 ? 
ATOM   2542 C  CA  . GLU   C 1 95  ? -11.129 -39.811 14.346  1.000 65.838  0  205 GLU   B CA  1 ? 
ATOM   2543 C  C   . GLU   C 1 95  ? -10.096 -38.672 14.399  1.000 53.928  0  205 GLU   B C   1 ? 
ATOM   2544 O  O   . GLU   C 1 95  ? -9.778  -38.179 15.480  1.000 47.851  0  205 GLU   B O   1 ? 
ATOM   2545 C  CB  . GLU   C 1 95  ? -10.538 -41.153 13.896  1.000 72.400  0  205 GLU   B CB  1 ? 
ATOM   2546 C  CG  . GLU   C 1 95  ? -9.854  -41.932 15.018  1.000 83.106  0  205 GLU   B CG  1 ? 
ATOM   2547 C  CD  . GLU   C 1 95  ? -9.347  -43.304 14.597  1.000 84.647  0  205 GLU   B CD  1 ? 
ATOM   2548 O  OE1 . GLU   C 1 95  ? -8.419  -43.359 13.766  1.000 82.188  0  205 GLU   B OE1 1 ? 
ATOM   2549 O  OE2 . GLU   C 1 95  ? -9.908  -44.317 15.071  1.000 86.353  0  205 GLU   B OE2 1 ? 
ATOM   2550 N  N   . PRO   C 1 96  ? -9.569  -38.188 13.243  1.000 45.509  0  206 PRO   B N   1 ? 
ATOM   2551 C  CA  . PRO   C 1 96  ? -8.553  -37.131 13.253  1.000 50.346  0  206 PRO   B CA  1 ? 
ATOM   2552 C  C   . PRO   C 1 96  ? -9.038  -35.772 13.776  1.000 47.213  0  206 PRO   B C   1 ? 
ATOM   2553 O  O   . PRO   C 1 96  ? -8.309  -35.093 14.492  1.000 49.200  0  206 PRO   B O   1 ? 
ATOM   2554 C  CB  . PRO   C 1 96  ? -8.093  -37.059 11.770  1.000 49.273  0  206 PRO   B CB  1 ? 
ATOM   2555 C  CG  . PRO   C 1 96  ? -9.246  -37.662 10.987  1.000 46.900  0  206 PRO   B CG  1 ? 
ATOM   2556 C  CD  . PRO   C 1 96  ? -9.824  -38.716 11.895  1.000 47.997  0  206 PRO   B CD  1 ? 
ATOM   2557 N  N   . VAL   C 1 97  ? -10.278 -35.394 13.423  1.000 43.705  0  207 VAL   B N   1 ? 
ATOM   2558 C  CA  . VAL   C 1 97  ? -10.826 -34.092 13.803  1.000 45.905  0  207 VAL   B CA  1 ? 
ATOM   2559 C  C   . VAL   C 1 97  ? -10.987 -34.027 15.327  1.000 41.729  0  207 VAL   B C   1 ? 
ATOM   2560 O  O   . VAL   C 1 97  ? -10.599 -33.037 15.948  1.000 39.324  0  207 VAL   B O   1 ? 
ATOM   2561 C  CB  . VAL   C 1 97  ? -12.158 -33.791 13.080  1.000 45.139  0  207 VAL   B CB  1 ? 
ATOM   2562 C  CG1 . VAL   C 1 97  ? -12.873 -32.577 13.670  1.000 43.297  0  207 VAL   B CG1 1 ? 
ATOM   2563 C  CG2 . VAL   C 1 97  ? -11.953 -33.602 11.582  1.000 44.688  0  207 VAL   B CG2 1 ? 
ATOM   2564 N  N   . LEU   C 1 98  ? -11.559 -35.092 15.916  1.000 41.368  0  208 LEU   B N   1 ? 
ATOM   2565 C  CA  . LEU   C 1 98  ? -11.810 -35.147 17.355  1.000 41.886  0  208 LEU   B CA  1 ? 
ATOM   2566 C  C   . LEU   C 1 98  ? -10.483 -35.133 18.122  1.000 40.789  0  208 LEU   B C   1 ? 
ATOM   2567 O  O   . LEU   C 1 98  ? -10.422 -34.635 19.242  1.000 44.465  0  208 LEU   B O   1 ? 
ATOM   2568 C  CB  . LEU   C 1 98  ? -12.637 -36.389 17.700  1.000 46.330  0  208 LEU   B CB  1 ? 
ATOM   2569 C  CG  . LEU   C 1 98  ? -13.012 -36.565 19.180  1.000 46.234  0  208 LEU   B CG  1 ? 
ATOM   2570 C  CD1 . LEU   C 1 98  ? -13.932 -35.450 19.658  1.000 48.275  0  208 LEU   B CD1 1 ? 
ATOM   2571 C  CD2 . LEU   C 1 98  ? -13.655 -37.921 19.421  1.000 45.364  0  208 LEU   B CD2 1 ? 
ATOM   2572 N  N   . GLU   C 1 99  ? -9.438  -35.720 17.524  1.000 42.309  0  209 GLU   B N   1 ? 
ATOM   2573 C  CA  . GLU   C 1 99  ? -8.128  -35.787 18.156  1.000 53.275  0  209 GLU   B CA  1 ? 
ATOM   2574 C  C   . GLU   C 1 99  ? -7.533  -34.380 18.269  1.000 51.986  0  209 GLU   B C   1 ? 
ATOM   2575 O  O   . GLU   C 1 99  ? -6.882  -34.063 19.263  1.000 52.888  0  209 GLU   B O   1 ? 
ATOM   2576 C  CB  . GLU   C 1 99  ? -7.191  -36.714 17.381  1.000 61.536  0  209 GLU   B CB  1 ? 
ATOM   2577 C  CG  . GLU   C 1 99  ? -5.834  -36.898 18.057  1.000 64.927  0  209 GLU   B CG  1 ? 
ATOM   2578 C  CD  . GLU   C 1 99  ? -4.911  -37.894 17.375  1.000 75.401  0  209 GLU   B CD  1 ? 
ATOM   2579 O  OE1 . GLU   C 1 99  ? -5.295  -38.444 16.319  1.000 81.600  0  209 GLU   B OE1 1 ? 
ATOM   2580 O  OE2 . GLU   C 1 99  ? -3.806  -38.127 17.912  1.000 79.012  0  209 GLU   B OE2 1 ? 
ATOM   2581 N  N   . VAL   C 1 100 ? -7.739  -33.554 17.229  1.000 47.498  0  210 VAL   B N   1 ? 
ATOM   2582 C  CA  . VAL   C 1 100 ? -7.229  -32.188 17.219  1.000 47.745  0  210 VAL   B CA  1 ? 
ATOM   2583 C  C   . VAL   C 1 100 ? -7.871  -31.415 18.371  1.000 42.961  0  210 VAL   B C   1 ? 
ATOM   2584 O  O   . VAL   C 1 100 ? -7.172  -30.789 19.161  1.000 39.395  0  210 VAL   B O   1 ? 
ATOM   2585 C  CB  . VAL   C 1 100 ? -7.467  -31.478 15.869  1.000 49.894  0  210 VAL   B CB  1 ? 
ATOM   2586 C  CG1 . VAL   C 1 100 ? -7.156  -29.985 15.946  1.000 49.609  0  210 VAL   B CG1 1 ? 
ATOM   2587 C  CG2 . VAL   C 1 100 ? -6.676  -32.126 14.740  1.000 47.921  0  210 VAL   B CG2 1 ? 
ATOM   2588 N  N   . TYR   C 1 101 ? -9.205  -31.496 18.469  1.000 38.074  0  211 TYR   B N   1 ? 
ATOM   2589 C  CA  . TYR   C 1 101 ? -9.950  -30.778 19.493  1.000 36.833  0  211 TYR   B CA  1 ? 
ATOM   2590 C  C   . TYR   C 1 101 ? -9.542  -31.279 20.877  1.000 39.234  0  211 TYR   B C   1 ? 
ATOM   2591 O  O   . TYR   C 1 101 ? -9.365  -30.483 21.796  1.000 39.274  0  211 TYR   B O   1 ? 
ATOM   2592 C  CB  . TYR   C 1 101 ? -11.457 -30.915 19.245  1.000 39.803  0  211 TYR   B CB  1 ? 
ATOM   2593 C  CG  . TYR   C 1 101 ? -12.003 -30.012 18.144  1.000 38.734  0  211 TYR   B CG  1 ? 
ATOM   2594 C  CD1 . TYR   C 1 101 ? -11.639 -28.672 18.069  1.000 38.976  0  211 TYR   B CD1 1 ? 
ATOM   2595 C  CD2 . TYR   C 1 101 ? -12.840 -30.511 17.153  1.000 41.004  0  211 TYR   B CD2 1 ? 
ATOM   2596 C  CE1 . TYR   C 1 101 ? -12.125 -27.846 17.071  1.000 41.900  0  211 TYR   B CE1 1 ? 
ATOM   2597 C  CE2 . TYR   C 1 101 ? -13.325 -29.698 16.141  1.000 40.966  0  211 TYR   B CE2 1 ? 
ATOM   2598 C  CZ  . TYR   C 1 101 ? -12.964 -28.361 16.099  1.000 40.987  0  211 TYR   B CZ  1 ? 
ATOM   2599 O  OH  . TYR   C 1 101 ? -13.437 -27.548 15.110  1.000 40.199  0  211 TYR   B OH  1 ? 
ATOM   2600 N  N   . GLN   C 1 102 ? -9.386  -32.601 21.010  1.000 37.577  0  212 GLN   B N   1 ? 
ATOM   2601 C  CA  . GLN   C 1 102 ? -8.998  -33.204 22.275  1.000 39.763  0  212 GLN   B CA  1 ? 
ATOM   2602 C  C   . GLN   C 1 102 ? -7.619  -32.692 22.696  1.000 37.912  0  212 GLN   B C   1 ? 
ATOM   2603 O  O   . GLN   C 1 102 ? -7.446  -32.231 23.822  1.000 37.398  0  212 GLN   B O   1 ? 
ATOM   2604 C  CB  . GLN   C 1 102 ? -9.027  -34.730 22.187  1.000 44.171  0  212 GLN   B CB  1 ? 
ATOM   2605 C  CG  . GLN   C 1 102 ? -10.423 -35.332 22.316  1.000 47.884  0  212 GLN   B CG  1 ? 
ATOM   2606 C  CD  . GLN   C 1 102 ? -10.453 -36.827 22.080  1.000 50.632  0  212 GLN   B CD  1 ? 
ATOM   2607 O  OE1 . GLN   C 1 102 ? -9.449  -37.442 21.706  1.000 64.483  0  212 GLN   B OE1 1 ? 
ATOM   2608 N  NE2 . GLN   C 1 102 ? -11.621 -37.425 22.272  1.000 52.619  0  212 GLN   B NE2 1 ? 
ATOM   2609 N  N   . ARG   C 1 103 ? -6.652  -32.741 21.772  1.000 43.031  0  213 ARG   B N   1 ? 
ATOM   2610 C  CA  . ARG   C 1 103 ? -5.273  -32.402 22.098  1.000 46.249  0  213 ARG   B CA  1 ? 
ATOM   2611 C  C   . ARG   C 1 103 ? -5.111  -30.883 22.236  1.000 47.040  0  213 ARG   B C   1 ? 
ATOM   2612 O  O   . ARG   C 1 103 ? -4.153  -30.420 22.853  1.000 48.395  0  213 ARG   B O   1 ? 
ATOM   2613 C  CB  . ARG   C 1 103 ? -4.285  -33.032 21.108  1.000 49.339  0  213 ARG   B CB  1 ? 
ATOM   2614 C  CG  . ARG   C 1 103 ? -4.069  -34.522 21.360  1.000 59.326  0  213 ARG   B CG  1 ? 
ATOM   2615 C  CD  . ARG   C 1 103 ? -2.704  -35.032 20.879  1.000 68.831  0  213 ARG   B CD  1 ? 
ATOM   2616 N  NE  . ARG   C 1 103 ? -2.674  -35.404 19.460  1.000 75.847  0  213 ARG   B NE  1 ? 
ATOM   2617 C  CZ  . ARG   C 1 103 ? -1.577  -35.794 18.802  1.000 75.395  0  213 ARG   B CZ  1 ? 
ATOM   2618 N  NH1 . ARG   C 1 103 ? -0.391  -35.712 19.382  1.000 71.575  0  213 ARG   B NH1 1 ? 
ATOM   2619 N  NH2 . ARG   C 1 103 ? -1.663  -36.189 17.541  1.000 76.842  0  213 ARG   B NH2 1 ? 
ATOM   2620 N  N   . LEU   C 1 104 ? -6.059  -30.116 21.678  1.000 43.139  0  214 LEU   B N   1 ? 
ATOM   2621 C  CA  . LEU   C 1 104 ? -6.097  -28.672 21.893  1.000 40.448  0  214 LEU   B CA  1 ? 
ATOM   2622 C  C   . LEU   C 1 104 ? -6.650  -28.382 23.290  1.000 36.001  0  214 LEU   B C   1 ? 
ATOM   2623 O  O   . LEU   C 1 104 ? -6.185  -27.469 23.968  1.000 40.087  0  214 LEU   B O   1 ? 
ATOM   2624 C  CB  . LEU   C 1 104 ? -6.931  -27.988 20.811  1.000 39.052  0  214 LEU   B CB  1 ? 
ATOM   2625 C  CG  . LEU   C 1 104 ? -6.277  -27.860 19.432  1.000 38.289  0  214 LEU   B CG  1 ? 
ATOM   2626 C  CD1 . LEU   C 1 104 ? -7.300  -27.401 18.406  1.000 41.391  0  214 LEU   B CD1 1 ? 
ATOM   2627 C  CD2 . LEU   C 1 104 ? -5.090  -26.910 19.464  1.000 40.034  0  214 LEU   B CD2 1 ? 
ATOM   2628 N  N   . HIS   C 1 105 ? -7.641  -29.179 23.707  1.000 36.419  0  215 HIS   B N   1 ? 
ATOM   2629 C  CA  . HIS   C 1 105 ? -8.307  -28.995 24.987  1.000 39.017  0  215 HIS   B CA  1 ? 
ATOM   2630 C  C   . HIS   C 1 105 ? -7.338  -29.313 26.135  1.000 40.427  0  215 HIS   B C   1 ? 
ATOM   2631 O  O   . HIS   C 1 105 ? -7.375  -28.661 27.176  1.000 42.071  0  215 HIS   B O   1 ? 
ATOM   2632 C  CB  . HIS   C 1 105 ? -9.581  -29.853 25.050  1.000 36.385  0  215 HIS   B CB  1 ? 
ATOM   2633 C  CG  . HIS   C 1 105 ? -10.495 -29.513 26.179  1.000 38.784  0  215 HIS   B CG  1 ? 
ATOM   2634 N  ND1 . HIS   C 1 105 ? -10.390 -30.075 27.431  1.000 44.469  0  215 HIS   B ND1 1 ? 
ATOM   2635 C  CD2 . HIS   C 1 105 ? -11.545 -28.679 26.237  1.000 38.509  0  215 HIS   B CD2 1 ? 
ATOM   2636 C  CE1 . HIS   C 1 105 ? -11.339 -29.581 28.214  1.000 39.883  0  215 HIS   B CE1 1 ? 
ATOM   2637 N  NE2 . HIS   C 1 105 ? -12.046 -28.727 27.511  1.000 36.045  0  215 HIS   B NE2 1 ? 
ATOM   2638 N  N   . SER   C 1 106 ? -6.454  -30.303 25.919  1.000 41.746  0  216 SER   B N   1 ? 
ATOM   2639 C  CA  . SER   C 1 106 ? -5.546  -30.775 26.960  1.000 45.842  0  216 SER   B CA  1 ? 
ATOM   2640 C  C   . SER   C 1 106 ? -4.134  -30.212 26.757  1.000 47.163  0  216 SER   B C   1 ? 
ATOM   2641 O  O   . SER   C 1 106 ? -3.225  -30.553 27.510  1.000 58.681  0  216 SER   B O   1 ? 
ATOM   2642 C  CB  . SER   C 1 106 ? -5.519  -32.280 27.003  1.000 39.853  0  216 SER   B CB  1 ? 
ATOM   2643 O  OG  . SER   C 1 106 ? -4.990  -32.812 25.797  1.000 42.752  0  216 SER   B OG  1 ? 
ATOM   2644 N  N   . ASP   C 1 107 ? -3.970  -29.325 25.760  1.000 51.925  0  217 ASP   B N   1 ? 
ATOM   2645 C  CA  . ASP   C 1 107 ? -2.658  -28.802 25.392  1.000 50.638  0  217 ASP   B CA  1 ? 
ATOM   2646 C  C   . ASP   C 1 107 ? -2.023  -28.102 26.597  1.000 52.682  0  217 ASP   B C   1 ? 
ATOM   2647 O  O   . ASP   C 1 107 ? -2.712  -27.451 27.380  1.000 50.064  0  217 ASP   B O   1 ? 
ATOM   2648 C  CB  . ASP   C 1 107 ? -2.749  -27.856 24.201  1.000 51.700  0  217 ASP   B CB  1 ? 
ATOM   2649 C  CG  . ASP   C 1 107 ? -1.427  -27.529 23.511  1.000 51.190  0  217 ASP   B CG  1 ? 
ATOM   2650 O  OD1 . ASP   C 1 107 ? -0.409  -28.174 23.844  1.000 46.547  0  217 ASP   B OD1 1 ? 
ATOM   2651 O  OD2 . ASP   C 1 107 ? -1.423  -26.624 22.653  1.000 43.631  0  217 ASP   B OD2 1 ? 
ATOM   2652 N  N   . LYS   C 1 108 ? -0.693  -28.241 26.717  1.000 67.782  0  218 LYS   B N   1 ? 
ATOM   2653 C  CA  . LYS   C 1 108 ? 0.075   -27.638 27.800  1.000 69.249  0  218 LYS   B CA  1 ? 
ATOM   2654 C  C   . LYS   C 1 108 ? 1.303   -26.944 27.210  1.000 58.616  0  218 LYS   B C   1 ? 
ATOM   2655 O  O   . LYS   C 1 108 ? 2.098   -27.575 26.519  1.000 67.085  0  218 LYS   B O   1 ? 
ATOM   2656 C  CB  . LYS   C 1 108 ? 0.505   -28.728 28.790  1.000 76.733  0  218 LYS   B CB  1 ? 
ATOM   2657 C  CG  . LYS   C 1 108 ? -0.634  -29.448 29.514  1.000 85.818  0  218 LYS   B CG  1 ? 
ATOM   2658 C  CD  . LYS   C 1 108 ? -0.433  -30.960 29.593  1.000 87.201  0  218 LYS   B CD  1 ? 
ATOM   2659 C  CE  . LYS   C 1 108 ? -1.510  -31.685 30.351  1.000 89.697  0  218 LYS   B CE  1 ? 
ATOM   2660 N  NZ  . LYS   C 1 108 ? -1.265  -31.685 31.797  1.000 100.531 0  218 LYS   B NZ  1 ? 
ATOM   2661 N  N   . GLY   C 1 109 ? 1.412   -25.628 27.444  1.000 57.507  0  219 GLY   B N   1 ? 
ATOM   2662 C  CA  . GLY   C 1 109 ? 2.554   -24.846 26.982  1.000 53.134  0  219 GLY   B CA  1 ? 
ATOM   2663 C  C   . GLY   C 1 109 ? 2.494   -24.565 25.476  1.000 59.040  0  219 GLY   B C   1 ? 
ATOM   2664 O  O   . GLY   C 1 109 ? 3.464   -24.077 24.899  1.000 65.198  0  219 GLY   B O   1 ? 
ATOM   2665 N  N   . GLY   C 1 110 ? 1.340   -24.860 24.854  1.000 60.686  0  220 GLY   B N   1 ? 
ATOM   2666 C  CA  . GLY   C 1 110 ? 1.151   -24.652 23.426  1.000 53.466  0  220 GLY   B CA  1 ? 
ATOM   2667 C  C   . GLY   C 1 110 ? 1.998   -25.616 22.592  1.000 52.646  0  220 GLY   B C   1 ? 
ATOM   2668 O  O   . GLY   C 1 110 ? 2.367   -25.296 21.463  1.000 63.392  0  220 GLY   B O   1 ? 
ATOM   2669 N  N   . SER   C 1 111 ? 2.258   -26.816 23.141  1.000 53.101  0  221 SER   B N   1 ? 
ATOM   2670 C  CA  . SER   C 1 111 ? 3.134   -27.786 22.492  1.000 52.089  0  221 SER   B CA  1 ? 
ATOM   2671 C  C   . SER   C 1 111 ? 2.438   -28.379 21.265  1.000 43.534  0  221 SER   B C   1 ? 
ATOM   2672 O  O   . SER   C 1 111 ? 3.007   -28.394 20.178  1.000 45.287  0  221 SER   B O   1 ? 
ATOM   2673 C  CB  . SER   C 1 111 ? 3.574   -28.873 23.453  1.000 52.140  0  221 SER   B CB  1 ? 
ATOM   2674 O  OG  . SER   C 1 111 ? 2.571   -29.871 23.601  1.000 70.048  0  221 SER   B OG  1 ? 
ATOM   2675 N  N   . PHE   C 1 112 ? 1.206   -28.876 21.462  1.000 46.378  0  222 PHE   B N   1 ? 
ATOM   2676 C  CA  . PHE   C 1 112 ? 0.422   -29.457 20.375  1.000 47.305  0  222 PHE   B CA  1 ? 
ATOM   2677 C  C   . PHE   C 1 112 ? 0.058   -28.363 19.373  1.000 46.184  0  222 PHE   B C   1 ? 
ATOM   2678 O  O   . PHE   C 1 112 ? 0.062   -28.599 18.166  1.000 47.321  0  222 PHE   B O   1 ? 
ATOM   2679 C  CB  . PHE   C 1 112 ? -0.836  -30.153 20.905  1.000 47.411  0  222 PHE   B CB  1 ? 
ATOM   2680 C  CG  . PHE   C 1 112 ? -1.743  -30.706 19.814  1.000 43.299  0  222 PHE   B CG  1 ? 
ATOM   2681 C  CD1 . PHE   C 1 112 ? -1.477  -31.937 19.218  1.000 39.601  0  222 PHE   B CD1 1 ? 
ATOM   2682 C  CD2 . PHE   C 1 112 ? -2.860  -29.992 19.381  1.000 39.754  0  222 PHE   B CD2 1 ? 
ATOM   2683 C  CE1 . PHE   C 1 112 ? -2.296  -32.427 18.211  1.000 45.300  0  222 PHE   B CE1 1 ? 
ATOM   2684 C  CE2 . PHE   C 1 112 ? -3.679  -30.494 18.378  1.000 37.969  0  222 PHE   B CE2 1 ? 
ATOM   2685 C  CZ  . PHE   C 1 112 ? -3.397  -31.708 17.797  1.000 40.641  0  222 PHE   B CZ  1 ? 
ATOM   2686 N  N   . GLU   C 1 113 ? -0.262  -27.170 19.895  1.000 45.950  0  223 GLU   B N   1 ? 
ATOM   2687 C  CA  . GLU   C 1 113 ? -0.596  -26.013 19.072  1.000 48.194  0  223 GLU   B CA  1 ? 
ATOM   2688 C  C   . GLU   C 1 113 ? 0.518   -25.779 18.045  1.000 46.548  0  223 GLU   B C   1 ? 
ATOM   2689 O  O   . GLU   C 1 113 ? 0.250   -25.685 16.848  1.000 44.193  0  223 GLU   B O   1 ? 
ATOM   2690 C  CB  . GLU   C 1 113 ? -0.805  -24.798 19.985  1.000 49.149  0  223 GLU   B CB  1 ? 
ATOM   2691 C  CG  . GLU   C 1 113 ? -1.328  -23.554 19.272  1.000 43.717  0  223 GLU   B CG  1 ? 
ATOM   2692 C  CD  . GLU   C 1 113 ? -1.484  -22.356 20.200  1.000 46.290  0  223 GLU   B CD  1 ? 
ATOM   2693 O  OE1 . GLU   C 1 113 ? -2.182  -22.499 21.220  1.000 48.637  0  223 GLU   B OE1 1 ? 
ATOM   2694 O  OE2 . GLU   C 1 113 ? -0.903  -21.288 19.912  1.000 42.202  0  223 GLU   B OE2 1 ? 
ATOM   2695 N  N   . ALA   C 1 114 ? 1.771   -25.749 18.532  1.000 43.152  0  224 ALA   B N   1 ? 
ATOM   2696 C  CA  . ALA   C 1 114 ? 2.937   -25.491 17.692  1.000 43.347  0  224 ALA   B CA  1 ? 
ATOM   2697 C  C   . ALA   C 1 114 ? 3.153   -26.639 16.701  1.000 45.348  0  224 ALA   B C   1 ? 
ATOM   2698 O  O   . ALA   C 1 114 ? 3.596   -26.412 15.577  1.000 45.008  0  224 ALA   B O   1 ? 
ATOM   2699 C  CB  . ALA   C 1 114 ? 4.157   -25.281 18.560  1.000 36.512  0  224 ALA   B CB  1 ? 
ATOM   2700 N  N   . ALA   C 1 115 ? 2.864   -27.870 17.143  1.000 47.935  0  225 ALA   B N   1 ? 
ATOM   2701 C  CA  . ALA   C 1 115 ? 3.021   -29.053 16.305  1.000 45.072  0  225 ALA   B CA  1 ? 
ATOM   2702 C  C   . ALA   C 1 115 ? 2.048   -28.998 15.129  1.000 50.844  0  225 ALA   B C   1 ? 
ATOM   2703 O  O   . ALA   C 1 115 ? 2.372   -29.448 14.032  1.000 52.305  0  225 ALA   B O   1 ? 
ATOM   2704 C  CB  . ALA   C 1 115 ? 2.810   -30.305 17.132  1.000 45.390  0  225 ALA   B CB  1 ? 
ATOM   2705 N  N   . LEU   C 1 116 ? 0.849   -28.454 15.381  1.000 51.124  0  226 LEU   B N   1 ? 
ATOM   2706 C  CA  . LEU   C 1 116 ? -0.188  -28.362 14.364  1.000 50.037  0  226 LEU   B CA  1 ? 
ATOM   2707 C  C   . LEU   C 1 116 ? 0.254   -27.375 13.277  1.000 50.546  0  226 LEU   B C   1 ? 
ATOM   2708 O  O   . LEU   C 1 116 ? -0.012  -27.589 12.099  1.000 49.279  0  226 LEU   B O   1 ? 
ATOM   2709 C  CB  . LEU   C 1 116 ? -1.504  -27.940 15.023  1.000 50.550  0  226 LEU   B CB  1 ? 
ATOM   2710 C  CG  . LEU   C 1 116 ? -2.788  -28.364 14.305  1.000 58.216  0  226 LEU   B CG  1 ? 
ATOM   2711 C  CD1 . LEU   C 1 116 ? -2.948  -29.875 14.317  1.000 56.730  0  226 LEU   B CD1 1 ? 
ATOM   2712 C  CD2 . LEU   C 1 116 ? -3.999  -27.699 14.934  1.000 67.323  0  226 LEU   B CD2 1 ? 
ATOM   2713 N  N   . TRP   C 1 117 ? 0.965   -26.313 13.692  1.000 45.117  0  227 TRP   B N   1 ? 
ATOM   2714 C  CA  . TRP   C 1 117 ? 1.485   -25.308 12.772  1.000 46.974  0  227 TRP   B CA  1 ? 
ATOM   2715 C  C   . TRP   C 1 117 ? 2.636   -25.890 11.949  1.000 50.565  0  227 TRP   B C   1 ? 
ATOM   2716 O  O   . TRP   C 1 117 ? 2.729   -25.648 10.747  1.000 55.216  0  227 TRP   B O   1 ? 
ATOM   2717 C  CB  . TRP   C 1 117 ? 1.940   -24.065 13.554  1.000 44.334  0  227 TRP   B CB  1 ? 
ATOM   2718 C  CG  . TRP   C 1 117 ? 2.458   -22.944 12.691  1.000 43.864  0  227 TRP   B CG  1 ? 
ATOM   2719 C  CD1 . TRP   C 1 117 ? 3.752   -22.723 12.317  1.000 44.630  0  227 TRP   B CD1 1 ? 
ATOM   2720 C  CD2 . TRP   C 1 117 ? 1.683   -21.878 12.101  1.000 44.166  0  227 TRP   B CD2 1 ? 
ATOM   2721 N  NE1 . TRP   C 1 117 ? 3.842   -21.589 11.552  1.000 41.851  0  227 TRP   B NE1 1 ? 
ATOM   2722 C  CE2 . TRP   C 1 117 ? 2.588   -21.053 11.396  1.000 44.878  0  227 TRP   B CE2 1 ? 
ATOM   2723 C  CE3 . TRP   C 1 117 ? 0.323   -21.541 12.101  1.000 42.011  0  227 TRP   B CE3 1 ? 
ATOM   2724 C  CZ2 . TRP   C 1 117 ? 2.171   -19.921 10.697  1.000 41.230  0  227 TRP   B CZ2 1 ? 
ATOM   2725 C  CZ3 . TRP   C 1 117 ? -0.085  -20.421 11.412  1.000 40.959  0  227 TRP   B CZ3 1 ? 
ATOM   2726 C  CH2 . TRP   C 1 117 ? 0.827   -19.623 10.721  1.000 43.768  0  227 TRP   B CH2 1 ? 
ATOM   2727 N  N   . GLN   C 1 118 ? 3.492   -26.677 12.613  1.000 51.123  0  228 GLN   B N   1 ? 
ATOM   2728 C  CA  . GLN   C 1 118 ? 4.704   -27.208 12.001  1.000 52.972  0  228 GLN   B CA  1 ? 
ATOM   2729 C  C   . GLN   C 1 118 ? 4.344   -28.162 10.855  1.000 48.656  0  228 GLN   B C   1 ? 
ATOM   2730 O  O   . GLN   C 1 118 ? 4.937   -28.089 9.779   1.000 54.827  0  228 GLN   B O   1 ? 
ATOM   2731 C  CB  . GLN   C 1 118 ? 5.535   -27.952 13.054  1.000 55.279  0  228 GLN   B CB  1 ? 
ATOM   2732 C  CG  . GLN   C 1 118 ? 7.013   -28.107 12.700  1.000 68.614  0  228 GLN   B CG  1 ? 
ATOM   2733 C  CD  . GLN   C 1 118 ? 7.871   -26.962 13.200  1.000 79.872  0  228 GLN   B CD  1 ? 
ATOM   2734 O  OE1 . GLN   C 1 118 ? 8.050   -26.776 14.410  1.000 77.318  0  228 GLN   B OE1 1 ? 
ATOM   2735 N  NE2 . GLN   C 1 118 ? 8.453   -26.210 12.274  1.000 82.931  0  228 GLN   B NE2 1 ? 
ATOM   2736 N  N   . GLN   C 1 119 ? 3.340   -29.029 11.090  1.000 42.130  0  229 GLN   B N   1 ? 
ATOM   2737 C  CA  . GLN   C 1 119 ? 3.088   -30.183 10.230  1.000 48.202  0  229 GLN   B CA  1 ? 
ATOM   2738 C  C   . GLN   C 1 119 ? 2.059   -29.854 9.142   1.000 48.740  0  229 GLN   B C   1 ? 
ATOM   2739 O  O   . GLN   C 1 119 ? 2.244   -30.233 7.989   1.000 60.894  0  229 GLN   B O   1 ? 
ATOM   2740 C  CB  . GLN   C 1 119 ? 2.643   -31.375 11.075  1.000 50.726  0  229 GLN   B CB  1 ? 
ATOM   2741 C  CG  . GLN   C 1 119 ? 3.747   -31.948 11.956  1.000 49.710  0  229 GLN   B CG  1 ? 
ATOM   2742 C  CD  . GLN   C 1 119 ? 3.291   -33.128 12.785  1.000 53.225  0  229 GLN   B CD  1 ? 
ATOM   2743 O  OE1 . GLN   C 1 119 ? 2.712   -34.090 12.270  1.000 67.312  0  229 GLN   B OE1 1 ? 
ATOM   2744 N  NE2 . GLN   C 1 119 ? 3.528   -33.055 14.088  1.000 52.867  0  229 GLN   B NE2 1 ? 
ATOM   2745 N  N   . TRP   C 1 120 ? 0.944   -29.222 9.533   1.000 52.554  0  230 TRP   B N   1 ? 
ATOM   2746 C  CA  . TRP   C 1 120 ? -0.135  -28.914 8.595   1.000 53.548  0  230 TRP   B CA  1 ? 
ATOM   2747 C  C   . TRP   C 1 120 ? 0.310   -27.829 7.613   1.000 50.571  0  230 TRP   B C   1 ? 
ATOM   2748 O  O   . TRP   C 1 120 ? 1.035   -26.907 7.986   1.000 42.316  0  230 TRP   B O   1 ? 
ATOM   2749 C  CB  . TRP   C 1 120 ? -1.399  -28.472 9.347   1.000 49.851  0  230 TRP   B CB  1 ? 
ATOM   2750 C  CG  . TRP   C 1 120 ? -2.150  -29.586 10.030  1.000 56.333  0  230 TRP   B CG  1 ? 
ATOM   2751 C  CD1 . TRP   C 1 120 ? -1.684  -30.824 10.364  1.000 58.374  0  230 TRP   B CD1 1 ? 
ATOM   2752 C  CD2 . TRP   C 1 120 ? -3.511  -29.527 10.512  1.000 55.667  0  230 TRP   B CD2 1 ? 
ATOM   2753 N  NE1 . TRP   C 1 120 ? -2.666  -31.548 10.992  1.000 60.233  0  230 TRP   B NE1 1 ? 
ATOM   2754 C  CE2 . TRP   C 1 120 ? -3.792  -30.776 11.105  1.000 54.829  0  230 TRP   B CE2 1 ? 
ATOM   2755 C  CE3 . TRP   C 1 120 ? -4.511  -28.546 10.497  1.000 63.067  0  230 TRP   B CE3 1 ? 
ATOM   2756 C  CZ2 . TRP   C 1 120 ? -5.033  -31.067 11.671  1.000 61.624  0  230 TRP   B CZ2 1 ? 
ATOM   2757 C  CZ3 . TRP   C 1 120 ? -5.736  -28.835 11.061  1.000 68.073  0  230 TRP   B CZ3 1 ? 
ATOM   2758 C  CH2 . TRP   C 1 120 ? -5.990  -30.077 11.641  1.000 59.860  0  230 TRP   B CH2 1 ? 
ATOM   2759 N  N   . ASP   C 1 121 ? -0.160  -27.938 6.359   1.000 53.412  0  231 ASP   B N   1 ? 
ATOM   2760 C  CA  . ASP   C 1 121 ? 0.083   -26.912 5.356   1.000 59.079  0  231 ASP   B CA  1 ? 
ATOM   2761 C  C   . ASP   C 1 121 ? -0.864  -25.742 5.618   1.000 57.745  0  231 ASP   B C   1 ? 
ATOM   2762 O  O   . ASP   C 1 121 ? -1.894  -25.905 6.270   1.000 55.688  0  231 ASP   B O   1 ? 
ATOM   2763 C  CB  . ASP   C 1 121 ? -0.022  -27.464 3.937   1.000 58.511  0  231 ASP   B CB  1 ? 
ATOM   2764 C  CG  . ASP   C 1 121 ? -1.412  -27.896 3.480   1.000 70.058  0  231 ASP   B CG  1 ? 
ATOM   2765 O  OD1 . ASP   C 1 121 ? -2.363  -27.753 4.268   1.000 81.524  0  231 ASP   B OD1 1 ? 
ATOM   2766 O  OD2 . ASP   C 1 121 ? -1.528  -28.362 2.329   1.000 79.550  0  231 ASP   B OD2 1 ? 
ATOM   2767 N  N   . ARG   C 1 122 ? -0.525  -24.582 5.052   1.000 50.784  0  232 ARG   B N   1 ? 
ATOM   2768 C  CA  . ARG   C 1 122 ? -1.226  -23.338 5.332   1.000 48.218  0  232 ARG   B CA  1 ? 
ATOM   2769 C  C   . ARG   C 1 122 ? -2.729  -23.503 5.079   1.000 48.118  0  232 ARG   B C   1 ? 
ATOM   2770 O  O   . ARG   C 1 122 ? -3.542  -23.032 5.866   1.000 44.633  0  232 ARG   B O   1 ? 
ATOM   2771 C  CB  . ARG   C 1 122 ? -0.628  -22.211 4.482   1.000 40.289  0  232 ARG   B CB  1 ? 
ATOM   2772 C  CG  . ARG   C 1 122 ? -1.079  -20.814 4.879   1.000 40.782  0  232 ARG   B CG  1 ? 
ATOM   2773 C  CD  . ARG   C 1 122 ? -0.193  -19.761 4.253   1.000 38.947  0  232 ARG   B CD  1 ? 
ATOM   2774 N  NE  . ARG   C 1 122 ? -0.436  -18.412 4.777   1.000 38.668  0  232 ARG   B NE  1 ? 
ATOM   2775 C  CZ  . ARG   C 1 122 ? -1.457  -17.618 4.458   1.000 43.048  0  232 ARG   B CZ  1 ? 
ATOM   2776 N  NH1 . ARG   C 1 122 ? -2.330  -17.982 3.529   1.000 44.289  0  232 ARG   B NH1 1 ? 
ATOM   2777 N  NH2 . ARG   C 1 122 ? -1.563  -16.426 5.029   1.000 49.662  0  232 ARG   B NH2 1 ? 
ATOM   2778 N  N   . GLN   C 1 123 ? -3.082  -24.209 3.996   1.000 52.273  0  233 GLN   B N   1 ? 
ATOM   2779 C  CA  . GLN   C 1 123 ? -4.474  -24.342 3.585   1.000 53.112  0  233 GLN   B CA  1 ? 
ATOM   2780 C  C   . GLN   C 1 123 ? -5.255  -25.161 4.619   1.000 51.893  0  233 GLN   B C   1 ? 
ATOM   2781 O  O   . GLN   C 1 123 ? -6.440  -24.911 4.839   1.000 44.081  0  233 GLN   B O   1 ? 
ATOM   2782 C  CB  . GLN   C 1 123 ? -4.568  -24.971 2.194   1.000 60.016  0  233 GLN   B CB  1 ? 
ATOM   2783 C  CG  . GLN   C 1 123 ? -5.987  -25.023 1.627   1.000 66.733  0  233 GLN   B CG  1 ? 
ATOM   2784 C  CD  . GLN   C 1 123 ? -6.598  -23.653 1.404   1.000 80.991  0  233 GLN   B CD  1 ? 
ATOM   2785 O  OE1 . GLN   C 1 123 ? -5.911  -22.624 1.423   1.000 88.196  0  233 GLN   B OE1 1 ? 
ATOM   2786 N  NE2 . GLN   C 1 123 ? -7.897  -23.634 1.136   1.000 91.391  0  233 GLN   B NE2 1 ? 
ATOM   2787 N  N   . SER   C 1 124 ? -4.591  -26.152 5.229   1.000 49.683  0  234 SER   B N   1 ? 
ATOM   2788 C  CA  . SER   C 1 124 ? -5.228  -26.996 6.234   1.000 51.211  0  234 SER   B CA  1 ? 
ATOM   2789 C  C   . SER   C 1 124 ? -5.605  -26.165 7.462   1.000 44.011  0  234 SER   B C   1 ? 
ATOM   2790 O  O   . SER   C 1 124 ? -6.698  -26.319 7.995   1.000 40.577  0  234 SER   B O   1 ? 
ATOM   2791 C  CB  . SER   C 1 124 ? -4.349  -28.163 6.611   1.000 54.225  0  234 SER   B CB  1 ? 
ATOM   2792 O  OG  . SER   C 1 124 ? -4.165  -29.040 5.509   1.000 57.985  0  234 SER   B OG  1 ? 
ATOM   2793 N  N   . LEU   C 1 125 ? -4.677  -25.293 7.906   1.000 47.206  0  235 LEU   B N   1 ? 
ATOM   2794 C  CA  . LEU   C 1 125 ? -4.918  -24.404 9.040   1.000 44.304  0  235 LEU   B CA  1 ? 
ATOM   2795 C  C   . LEU   C 1 125 ? -6.157  -23.549 8.754   1.000 42.341  0  235 LEU   B C   1 ? 
ATOM   2796 O  O   . LEU   C 1 125 ? -7.065  -23.467 9.577   1.000 38.158  0  235 LEU   B O   1 ? 
ATOM   2797 C  CB  . LEU   C 1 125 ? -3.699  -23.511 9.325   1.000 46.399  0  235 LEU   B CB  1 ? 
ATOM   2798 C  CG  . LEU   C 1 125 ? -2.508  -24.150 10.060  1.000 56.914  0  235 LEU   B CG  1 ? 
ATOM   2799 C  CD1 . LEU   C 1 125 ? -2.932  -24.826 11.358  1.000 57.842  0  235 LEU   B CD1 1 ? 
ATOM   2800 C  CD2 . LEU   C 1 125 ? -1.748  -25.114 9.184   1.000 60.761  0  235 LEU   B CD2 1 ? 
ATOM   2801 N  N   . ILE   C 1 126 ? -6.180  -22.933 7.566   1.000 37.416  0  236 ILE   B N   1 ? 
ATOM   2802 C  CA  . ILE   C 1 126 ? -7.212  -21.975 7.195   1.000 40.832  0  236 ILE   B CA  1 ? 
ATOM   2803 C  C   . ILE   C 1 126 ? -8.592  -22.642 7.231   1.000 38.745  0  236 ILE   B C   1 ? 
ATOM   2804 O  O   . ILE   C 1 126 ? -9.550  -22.057 7.740   1.000 38.825  0  236 ILE   B O   1 ? 
ATOM   2805 C  CB  . ILE   C 1 126 ? -6.898  -21.360 5.817   1.000 42.750  0  236 ILE   B CB  1 ? 
ATOM   2806 C  CG1 . ILE   C 1 126 ? -5.647  -20.455 5.891   1.000 47.350  0  236 ILE   B CG1 1 ? 
ATOM   2807 C  CG2 . ILE   C 1 126 ? -8.113  -20.613 5.254   1.000 41.340  0  236 ILE   B CG2 1 ? 
ATOM   2808 C  CD1 . ILE   C 1 126 ? -5.251  -19.819 4.570   1.000 44.771  0  236 ILE   B CD1 1 ? 
ATOM   2809 N  N   . MET   C 1 127 ? -8.688  -23.850 6.670   1.000 37.484  0  237 MET   B N   1 ? 
ATOM   2810 C  CA  . MET   C 1 127 ? -9.953  -24.567 6.603   1.000 42.331  0  237 MET   B CA  1 ? 
ATOM   2811 C  C   . MET   C 1 127 ? -10.447 -24.887 8.015   1.000 40.981  0  237 MET   B C   1 ? 
ATOM   2812 O  O   . MET   C 1 127 ? -11.634 -24.744 8.305   1.000 40.887  0  237 MET   B O   1 ? 
ATOM   2813 C  CB  . MET   C 1 127 ? -9.811  -25.866 5.802   1.000 46.820  0  237 MET   B CB  1 ? 
ATOM   2814 C  CG  . MET   C 1 127 ? -9.554  -25.666 4.309   1.000 60.507  0  237 MET   B CG  1 ? 
ATOM   2815 S  SD  . MET   C 1 127 ? -11.010 -25.141 3.378   1.000 75.127  0  237 MET   B SD  1 ? 
ATOM   2816 C  CE  . MET   C 1 127 ? -10.981 -23.348 3.524   1.000 68.501  0  237 MET   B CE  1 ? 
ATOM   2817 N  N   . PHE   C 1 128 ? -9.518  -25.284 8.893   1.000 39.519  0  238 PHE   B N   1 ? 
ATOM   2818 C  CA  . PHE   C 1 128 ? -9.866  -25.731 10.232  1.000 39.393  0  238 PHE   B CA  1 ? 
ATOM   2819 C  C   . PHE   C 1 128 ? -10.266 -24.535 11.096  1.000 38.935  0  238 PHE   B C   1 ? 
ATOM   2820 O  O   . PHE   C 1 128 ? -11.218 -24.623 11.868  1.000 43.173  0  238 PHE   B O   1 ? 
ATOM   2821 C  CB  . PHE   C 1 128 ? -8.706  -26.501 10.862  1.000 41.457  0  238 PHE   B CB  1 ? 
ATOM   2822 C  CG  . PHE   C 1 128 ? -9.101  -27.318 12.085  1.000 46.870  0  238 PHE   B CG  1 ? 
ATOM   2823 C  CD1 . PHE   C 1 128 ? -9.081  -26.757 13.359  1.000 53.627  0  238 PHE   B CD1 1 ? 
ATOM   2824 C  CD2 . PHE   C 1 128 ? -9.527  -28.638 11.952  1.000 49.745  0  238 PHE   B CD2 1 ? 
ATOM   2825 C  CE1 . PHE   C 1 128 ? -9.456  -27.503 14.469  1.000 58.036  0  238 PHE   B CE1 1 ? 
ATOM   2826 C  CE2 . PHE   C 1 128 ? -9.907  -29.377 13.064  1.000 53.501  0  238 PHE   B CE2 1 ? 
ATOM   2827 C  CZ  . PHE   C 1 128 ? -9.867  -28.811 14.318  1.000 56.859  0  238 PHE   B CZ  1 ? 
ATOM   2828 N  N   . ILE   C 1 129 ? -9.511  -23.427 10.975  1.000 38.429  0  239 ILE   B N   1 ? 
ATOM   2829 C  CA  . ILE   C 1 129 ? -9.728  -22.244 11.801  1.000 38.639  0  239 ILE   B CA  1 ? 
ATOM   2830 C  C   . ILE   C 1 129 ? -11.076 -21.609 11.447  1.000 31.400  0  239 ILE   B C   1 ? 
ATOM   2831 O  O   . ILE   C 1 129 ? -11.868 -21.310 12.335  1.000 36.182  0  239 ILE   B O   1 ? 
ATOM   2832 C  CB  . ILE   C 1 129 ? -8.559  -21.247 11.657  1.000 38.779  0  239 ILE   B CB  1 ? 
ATOM   2833 C  CG1 . ILE   C 1 129 ? -7.279  -21.791 12.313  1.000 35.947  0  239 ILE   B CG1 1 ? 
ATOM   2834 C  CG2 . ILE   C 1 129 ? -8.935  -19.870 12.218  1.000 36.285  0  239 ILE   B CG2 1 ? 
ATOM   2835 C  CD1 . ILE   C 1 129 ? -6.033  -20.972 12.021  1.000 32.693  0  239 ILE   B CD1 1 ? 
ATOM   2836 N  N   . THR   C 1 130 ? -11.314 -21.397 10.146  1.000 30.504  0  240 THR   B N   1 ? 
ATOM   2837 C  CA  . THR   C 1 130 ? -12.552 -20.778 9.675   1.000 35.785  0  240 THR   B CA  1 ? 
ATOM   2838 C  C   . THR   C 1 130 ? -13.751 -21.609 10.142  1.000 31.197  0  240 THR   B C   1 ? 
ATOM   2839 O  O   . THR   C 1 130 ? -14.755 -21.059 10.578  1.000 34.921  0  240 THR   B O   1 ? 
ATOM   2840 C  CB  . THR   C 1 130 ? -12.526 -20.641 8.151   1.000 35.870  0  240 THR   B CB  1 ? 
ATOM   2841 O  OG1 . THR   C 1 130 ? -11.382 -19.845 7.856   1.000 43.690  0  240 THR   B OG1 1 ? 
ATOM   2842 C  CG2 . THR   C 1 130 ? -13.772 -19.967 7.601   1.000 30.528  0  240 THR   B CG2 1 ? 
ATOM   2843 N  N   . ALA   C 1 131 ? -13.635 -22.934 10.025  1.000 32.012  0  241 ALA   B N   1 ? 
ATOM   2844 C  CA  . ALA   C 1 131 ? -14.707 -23.839 10.409  1.000 35.716  0  241 ALA   B CA  1 ? 
ATOM   2845 C  C   . ALA   C 1 131 ? -14.989 -23.722 11.909  1.000 35.319  0  241 ALA   B C   1 ? 
ATOM   2846 O  O   . ALA   C 1 131 ? -16.132 -23.535 12.314  1.000 33.732  0  241 ALA   B O   1 ? 
ATOM   2847 C  CB  . ALA   C 1 131 ? -14.348 -25.254 10.019  1.000 39.565  0  241 ALA   B CB  1 ? 
ATOM   2848 N  N   . PHE   C 1 132 ? -13.927 -23.775 12.722  1.000 33.928  0  242 PHE   B N   1 ? 
ATOM   2849 C  CA  . PHE   C 1 132 ? -14.072 -23.736 14.169  1.000 35.264  0  242 PHE   B CA  1 ? 
ATOM   2850 C  C   . PHE   C 1 132 ? -14.755 -22.434 14.594  1.000 31.878  0  242 PHE   B C   1 ? 
ATOM   2851 O  O   . PHE   C 1 132 ? -15.770 -22.465 15.285  1.000 35.076  0  242 PHE   B O   1 ? 
ATOM   2852 C  CB  . PHE   C 1 132 ? -12.730 -23.887 14.883  1.000 34.347  0  242 PHE   B CB  1 ? 
ATOM   2853 C  CG  . PHE   C 1 132 ? -12.815 -23.594 16.372  1.000 32.093  0  242 PHE   B CG  1 ? 
ATOM   2854 C  CD1 . PHE   C 1 132 ? -13.336 -24.533 17.256  1.000 33.783  0  242 PHE   B CD1 1 ? 
ATOM   2855 C  CD2 . PHE   C 1 132 ? -12.447 -22.351 16.874  1.000 36.226  0  242 PHE   B CD2 1 ? 
ATOM   2856 C  CE1 . PHE   C 1 132 ? -13.454 -24.244 18.610  1.000 35.177  0  242 PHE   B CE1 1 ? 
ATOM   2857 C  CE2 . PHE   C 1 132 ? -12.563 -22.072 18.227  1.000 38.932  0  242 PHE   B CE2 1 ? 
ATOM   2858 C  CZ  . PHE   C 1 132 ? -13.063 -23.020 19.091  1.000 36.119  0  242 PHE   B CZ  1 ? 
ATOM   2859 N  N   . LEU   C 1 133 ? -14.171 -21.295 14.196  1.000 33.689  0  243 LEU   B N   1 ? 
ATOM   2860 C  CA  . LEU   C 1 133 ? -14.652 -19.984 14.628  1.000 37.082  0  243 LEU   B CA  1 ? 
ATOM   2861 C  C   . LEU   C 1 133 ? -16.149 -19.839 14.331  1.000 37.469  0  243 LEU   B C   1 ? 
ATOM   2862 O  O   . LEU   C 1 133 ? -16.878 -19.244 15.120  1.000 44.546  0  243 LEU   B O   1 ? 
ATOM   2863 C  CB  . LEU   C 1 133 ? -13.840 -18.874 13.960  1.000 36.352  0  243 LEU   B CB  1 ? 
ATOM   2864 C  CG  . LEU   C 1 133 ? -12.403 -18.683 14.465  1.000 37.802  0  243 LEU   B CG  1 ? 
ATOM   2865 C  CD1 . LEU   C 1 133 ? -11.697 -17.638 13.625  1.000 36.145  0  243 LEU   B CD1 1 ? 
ATOM   2866 C  CD2 . LEU   C 1 133 ? -12.351 -18.296 15.945  1.000 38.757  0  243 LEU   B CD2 1 ? 
ATOM   2867 N  N   . ASN   C 1 134 ? -16.595 -20.389 13.190  1.000 34.134  0  244 ASN   B N   1 ? 
ATOM   2868 C  CA  . ASN   C 1 134 ? -17.995 -20.309 12.791  1.000 37.196  0  244 ASN   B CA  1 ? 
ATOM   2869 C  C   . ASN   C 1 134 ? -18.851 -21.234 13.665  1.000 40.074  0  244 ASN   B C   1 ? 
ATOM   2870 O  O   . ASN   C 1 134 ? -19.974 -20.886 14.012  1.000 55.804  0  244 ASN   B O   1 ? 
ATOM   2871 C  CB  . ASN   C 1 134 ? -18.167 -20.592 11.300  1.000 35.154  0  244 ASN   B CB  1 ? 
ATOM   2872 C  CG  . ASN   C 1 134 ? -17.819 -19.387 10.453  1.000 38.234  0  244 ASN   B CG  1 ? 
ATOM   2873 O  OD1 . ASN   C 1 134 ? -18.543 -18.383 10.476  1.000 36.630  0  244 ASN   B OD1 1 ? 
ATOM   2874 N  ND2 . ASN   C 1 134 ? -16.721 -19.455 9.712   1.000 39.632  0  244 ASN   B ND2 1 ? 
ATOM   2875 N  N   . ILE   C 1 135 ? -18.288 -22.387 14.052  1.000 41.376  0  245 ILE   B N   1 ? 
ATOM   2876 C  CA  . ILE   C 1 135 ? -19.020 -23.398 14.813  1.000 43.244  0  245 ILE   B CA  1 ? 
ATOM   2877 C  C   . ILE   C 1 135 ? -19.107 -22.987 16.289  1.000 39.418  0  245 ILE   B C   1 ? 
ATOM   2878 O  O   . ILE   C 1 135 ? -20.170 -23.088 16.902  1.000 33.942  0  245 ILE   B O   1 ? 
ATOM   2879 C  CB  . ILE   C 1 135 ? -18.353 -24.783 14.652  1.000 54.550  0  245 ILE   B CB  1 ? 
ATOM   2880 C  CG1 . ILE   C 1 135 ? -18.374 -25.261 13.195  1.000 62.387  0  245 ILE   B CG1 1 ? 
ATOM   2881 C  CG2 . ILE   C 1 135 ? -18.986 -25.815 15.588  1.000 65.720  0  245 ILE   B CG2 1 ? 
ATOM   2882 C  CD1 . ILE   C 1 135 ? -19.754 -25.605 12.669  1.000 57.762  0  245 ILE   B CD1 1 ? 
ATOM   2883 N  N   . ALA   C 1 136 ? -17.975 -22.532 16.847  1.000 37.796  0  246 ALA   B N   1 ? 
ATOM   2884 C  CA  . ALA   C 1 136 ? -17.807 -22.394 18.294  1.000 38.161  0  246 ALA   B CA  1 ? 
ATOM   2885 C  C   . ALA   C 1 136 ? -18.878 -21.486 18.908  1.000 39.742  0  246 ALA   B C   1 ? 
ATOM   2886 O  O   . ALA   C 1 136 ? -19.366 -21.762 20.000  1.000 44.201  0  246 ALA   B O   1 ? 
ATOM   2887 C  CB  . ALA   C 1 136 ? -16.420 -21.878 18.599  1.000 36.231  0  246 ALA   B CB  1 ? 
ATOM   2888 N  N   . LEU   C 1 137 ? -19.245 -20.414 18.194  1.000 41.500  0  247 LEU   B N   1 ? 
ATOM   2889 C  CA  . LEU   C 1 137 ? -20.066 -19.350 18.765  1.000 43.691  0  247 LEU   B CA  1 ? 
ATOM   2890 C  C   . LEU   C 1 137 ? -21.544 -19.764 18.859  1.000 49.208  0  247 LEU   B C   1 ? 
ATOM   2891 O  O   . LEU   C 1 137 ? -22.334 -19.057 19.484  1.000 45.989  0  247 LEU   B O   1 ? 
ATOM   2892 C  CB  . LEU   C 1 137 ? -19.893 -18.081 17.930  1.000 46.527  0  247 LEU   B CB  1 ? 
ATOM   2893 C  CG  . LEU   C 1 137 ? -18.519 -17.408 18.015  1.000 52.899  0  247 LEU   B CG  1 ? 
ATOM   2894 C  CD1 . LEU   C 1 137 ? -18.376 -16.331 16.962  1.000 52.036  0  247 LEU   B CD1 1 ? 
ATOM   2895 C  CD2 . LEU   C 1 137 ? -18.284 -16.831 19.401  1.000 48.213  0  247 LEU   B CD2 1 ? 
ATOM   2896 N  N   . GLN   C 1 138 ? -21.909 -20.912 18.253  1.000 46.586  0  248 GLN   B N   1 ? 
ATOM   2897 C  CA  . GLN   C 1 138 ? -23.303 -21.353 18.226  1.000 50.516  0  248 GLN   B CA  1 ? 
ATOM   2898 C  C   . GLN   C 1 138 ? -23.522 -22.562 19.150  1.000 45.347  0  248 GLN   B C   1 ? 
ATOM   2899 O  O   . GLN   C 1 138 ? -24.661 -22.868 19.501  1.000 43.012  0  248 GLN   B O   1 ? 
ATOM   2900 C  CB  . GLN   C 1 138 ? -23.731 -21.673 16.796  1.000 59.078  0  248 GLN   B CB  1 ? 
ATOM   2901 C  CG  . GLN   C 1 138 ? -23.845 -20.445 15.897  1.000 74.704  0  248 GLN   B CG  1 ? 
ATOM   2902 C  CD  . GLN   C 1 138 ? -24.274 -20.778 14.483  1.000 96.135  0  248 GLN   B CD  1 ? 
ATOM   2903 O  OE1 . GLN   C 1 138 ? -24.464 -21.945 14.122  1.000 106.864 0  248 GLN   B OE1 1 ? 
ATOM   2904 N  NE2 . GLN   C 1 138 ? -24.427 -19.747 13.663  1.000 109.140 0  248 GLN   B NE2 1 ? 
ATOM   2905 N  N   . LEU   C 1 139 ? -22.432 -23.236 19.546  1.000 41.022  0  249 LEU   B N   1 ? 
ATOM   2906 C  CA  . LEU   C 1 139 ? -22.531 -24.447 20.356  1.000 45.477  0  249 LEU   B CA  1 ? 
ATOM   2907 C  C   . LEU   C 1 139 ? -22.457 -24.097 21.842  1.000 45.513  0  249 LEU   B C   1 ? 
ATOM   2908 O  O   . LEU   C 1 139 ? -21.707 -23.201 22.242  1.000 37.096  0  249 LEU   B O   1 ? 
ATOM   2909 C  CB  . LEU   C 1 139 ? -21.446 -25.449 19.962  1.000 58.495  0  249 LEU   B CB  1 ? 
ATOM   2910 C  CG  . LEU   C 1 139 ? -21.860 -26.517 18.941  1.000 69.013  0  249 LEU   B CG  1 ? 
ATOM   2911 C  CD1 . LEU   C 1 139 ? -22.535 -25.921 17.710  1.000 68.420  0  249 LEU   B CD1 1 ? 
ATOM   2912 C  CD2 . LEU   C 1 139 ? -20.655 -27.342 18.540  1.000 74.363  0  249 LEU   B CD2 1 ? 
ATOM   2913 N  N   . PRO   C 1 140 ? -23.242 -24.796 22.707  1.000 37.081  0  250 PRO   B N   1 ? 
ATOM   2914 C  CA  . PRO   C 1 140 ? -23.146 -24.613 24.154  1.000 34.739  0  250 PRO   B CA  1 ? 
ATOM   2915 C  C   . PRO   C 1 140 ? -21.765 -25.002 24.666  1.000 35.339  0  250 PRO   B C   1 ? 
ATOM   2916 O  O   . PRO   C 1 140 ? -21.147 -25.934 24.144  1.000 33.424  0  250 PRO   B O   1 ? 
ATOM   2917 C  CB  . PRO   C 1 140 ? -24.261 -25.529 24.731  1.000 34.330  0  250 PRO   B CB  1 ? 
ATOM   2918 C  CG  . PRO   C 1 140 ? -25.191 -25.789 23.550  1.000 35.183  0  250 PRO   B CG  1 ? 
ATOM   2919 C  CD  . PRO   C 1 140 ? -24.312 -25.727 22.322  1.000 35.574  0  250 PRO   B CD  1 ? 
ATOM   2920 N  N   . CYS   C 1 141 ? -21.300 -24.292 25.704  1.000 35.806  0  251 CYS   B N   1 ? 
ATOM   2921 C  CA  . CYS   C 1 141 ? -20.000 -24.564 26.304  1.000 38.862  0  251 CYS   B CA  1 ? 
ATOM   2922 C  C   . CYS   C 1 141 ? -20.148 -25.561 27.455  1.000 35.933  0  251 CYS   B C   1 ? 
ATOM   2923 O  O   . CYS   C 1 141 ? -19.154 -26.058 27.971  1.000 42.832  0  251 CYS   B O   1 ? 
ATOM   2924 C  CB  . CYS   C 1 141 ? -19.324 -23.278 26.762  1.000 36.460  0  251 CYS   B CB  1 ? 
ATOM   2925 S  SG  . CYS   C 1 141 ? -20.314 -22.311 27.924  1.000 45.325  0  251 CYS   B SG  1 ? 
ATOM   2926 N  N   . GLU   C 1 142 ? -21.403 -25.839 27.848  1.000 41.687  0  252 GLU   B N   1 ? 
ATOM   2927 C  CA  . GLU   C 1 142 ? -21.706 -26.811 28.892  1.000 43.200  0  252 GLU   B CA  1 ? 
ATOM   2928 C  C   . GLU   C 1 142 ? -22.776 -27.775 28.375  1.000 44.683  0  252 GLU   B C   1 ? 
ATOM   2929 O  O   . GLU   C 1 142 ? -23.537 -27.429 27.472  1.000 50.338  0  252 GLU   B O   1 ? 
ATOM   2930 C  CB  . GLU   C 1 142 ? -22.177 -26.087 30.155  1.000 40.725  0  252 GLU   B CB  1 ? 
ATOM   2931 C  CG  . GLU   C 1 142 ? -21.119 -25.165 30.762  1.000 44.948  0  252 GLU   B CG  1 ? 
ATOM   2932 C  CD  . GLU   C 1 142 ? -19.975 -25.875 31.474  1.000 44.275  0  252 GLU   B CD  1 ? 
ATOM   2933 O  OE1 . GLU   C 1 142 ? -20.138 -27.059 31.844  1.000 39.083  0  252 GLU   B OE1 1 ? 
ATOM   2934 O  OE2 . GLU   C 1 142 ? -18.896 -25.258 31.601  1.000 42.644  0  252 GLU   B OE2 1 ? 
ATOM   2935 N  N   . SER   C 1 143 ? -22.813 -28.989 28.949  1.000 43.611  0  253 SER   B N   1 ? 
ATOM   2936 C  CA  . SER   C 1 143 ? -23.771 -30.013 28.531  1.000 48.191  0  253 SER   B CA  1 ? 
ATOM   2937 C  C   . SER   C 1 143 ? -24.451 -30.666 29.741  1.000 46.345  0  253 SER   B C   1 ? 
ATOM   2938 O  O   . SER   C 1 143 ? -25.557 -31.189 29.614  1.000 51.229  0  253 SER   B O   1 ? 
ATOM   2939 C  CB  . SER   C 1 143 ? -23.112 -31.044 27.661  1.000 50.167  0  253 SER   B CB  1 ? 
ATOM   2940 O  OG  . SER   C 1 143 ? -21.998 -31.630 28.315  1.000 52.431  0  253 SER   B OG  1 ? 
ATOM   2941 N  N   . SER   C 1 144 ? -23.755 -30.695 30.888  1.000 41.554  0  254 SER   B N   1 ? 
ATOM   2942 C  CA  . SER   C 1 144 ? -24.312 -31.245 32.117  1.000 41.828  0  254 SER   B CA  1 ? 
ATOM   2943 C  C   . SER   C 1 144 ? -25.757 -30.765 32.299  1.000 44.838  0  254 SER   B C   1 ? 
ATOM   2944 O  O   . SER   C 1 144 ? -26.007 -29.570 32.437  1.000 42.045  0  254 SER   B O   1 ? 
ATOM   2945 C  CB  . SER   C 1 144 ? -23.460 -30.881 33.302  1.000 42.413  0  254 SER   B CB  1 ? 
ATOM   2946 O  OG  . SER   C 1 144 ? -24.102 -31.229 34.518  1.000 48.949  0  254 SER   B OG  1 ? 
ATOM   2947 N  N   . ALA   C 1 145 ? -26.694 -31.723 32.325  1.000 49.168  0  255 ALA   B N   1 ? 
ATOM   2948 C  CA  . ALA   C 1 145 ? -28.121 -31.425 32.370  1.000 44.888  0  255 ALA   B CA  1 ? 
ATOM   2949 C  C   . ALA   C 1 145 ? -28.463 -30.598 33.612  1.000 40.807  0  255 ALA   B C   1 ? 
ATOM   2950 O  O   . ALA   C 1 145 ? -29.288 -29.687 33.542  1.000 41.352  0  255 ALA   B O   1 ? 
ATOM   2951 C  CB  . ALA   C 1 145 ? -28.915 -32.713 32.332  1.000 45.108  0  255 ALA   B CB  1 ? 
ATOM   2952 N  N   . VAL   C 1 146 ? -27.842 -30.936 34.749  1.000 37.740  0  256 VAL   B N   1 ? 
ATOM   2953 C  CA  . VAL   C 1 146 ? -28.125 -30.251 36.004  1.000 40.821  0  256 VAL   B CA  1 ? 
ATOM   2954 C  C   . VAL   C 1 146 ? -27.625 -28.805 35.904  1.000 41.159  0  256 VAL   B C   1 ? 
ATOM   2955 O  O   . VAL   C 1 146 ? -28.323 -27.879 36.312  1.000 49.320  0  256 VAL   B O   1 ? 
ATOM   2956 C  CB  . VAL   C 1 146 ? -27.531 -30.975 37.237  1.000 45.314  0  256 VAL   B CB  1 ? 
ATOM   2957 C  CG1 . VAL   C 1 146 ? -26.005 -31.007 37.225  1.000 50.866  0  256 VAL   B CG1 1 ? 
ATOM   2958 C  CG2 . VAL   C 1 146 ? -28.037 -30.372 38.541  1.000 53.604  0  256 VAL   B CG2 1 ? 
ATOM   2959 N  N   . VAL   C 1 147 ? -26.435 -28.623 35.310  1.000 42.045  0  257 VAL   B N   1 ? 
ATOM   2960 C  CA  . VAL   C 1 147 ? -25.838 -27.302 35.159  1.000 37.747  0  257 VAL   B CA  1 ? 
ATOM   2961 C  C   . VAL   C 1 147 ? -26.676 -26.480 34.183  1.000 37.619  0  257 VAL   B C   1 ? 
ATOM   2962 O  O   . VAL   C 1 147 ? -27.019 -25.337 34.473  1.000 38.839  0  257 VAL   B O   1 ? 
ATOM   2963 C  CB  . VAL   C 1 147 ? -24.372 -27.400 34.692  1.000 39.607  0  257 VAL   B CB  1 ? 
ATOM   2964 C  CG1 . VAL   C 1 147 ? -23.824 -26.051 34.234  1.000 39.430  0  257 VAL   B CG1 1 ? 
ATOM   2965 C  CG2 . VAL   C 1 147 ? -23.478 -28.009 35.768  1.000 38.526  0  257 VAL   B CG2 1 ? 
ATOM   2966 N  N   . VAL   C 1 148 ? -27.010 -27.085 33.032  1.000 37.915  0  258 VAL   B N   1 ? 
ATOM   2967 C  CA  . VAL   C 1 148 ? -27.723 -26.394 31.965  1.000 38.074  0  258 VAL   B CA  1 ? 
ATOM   2968 C  C   . VAL   C 1 148 ? -29.102 -25.963 32.464  1.000 34.751  0  258 VAL   B C   1 ? 
ATOM   2969 O  O   . VAL   C 1 148 ? -29.528 -24.837 32.215  1.000 40.317  0  258 VAL   B O   1 ? 
ATOM   2970 C  CB  . VAL   C 1 148 ? -27.828 -27.274 30.702  1.000 39.387  0  258 VAL   B CB  1 ? 
ATOM   2971 C  CG1 . VAL   C 1 148 ? -28.832 -26.722 29.697  1.000 36.100  0  258 VAL   B CG1 1 ? 
ATOM   2972 C  CG2 . VAL   C 1 148 ? -26.468 -27.468 30.041  1.000 44.912  0  258 VAL   B CG2 1 ? 
ATOM   2973 N  N   . SER   C 1 149 ? -29.802 -26.875 33.146  1.000 34.321  0  259 SER   B N   1 ? 
ATOM   2974 C  CA  . SER   C 1 149 ? -31.132 -26.588 33.667  1.000 36.549  0  259 SER   B CA  1 ? 
ATOM   2975 C  C   . SER   C 1 149 ? -31.072 -25.421 34.652  1.000 36.902  0  259 SER   B C   1 ? 
ATOM   2976 O  O   . SER   C 1 149 ? -31.921 -24.536 34.616  1.000 37.679  0  259 SER   B O   1 ? 
ATOM   2977 C  CB  . SER   C 1 149 ? -31.743 -27.807 34.302  1.000 36.981  0  259 SER   B CB  1 ? 
ATOM   2978 O  OG  . SER   C 1 149 ? -31.882 -28.854 33.354  1.000 45.315  0  259 SER   B OG  1 ? 
ATOM   2979 N  N   . GLY   C 1 150 ? -30.049 -25.430 35.518  1.000 35.615  0  260 GLY   B N   1 ? 
ATOM   2980 C  CA  . GLY   C 1 150 ? -29.878 -24.397 36.529  1.000 37.860  0  260 GLY   B CA  1 ? 
ATOM   2981 C  C   . GLY   C 1 150 ? -29.590 -23.032 35.903  1.000 33.721  0  260 GLY   B C   1 ? 
ATOM   2982 O  O   . GLY   C 1 150 ? -30.258 -22.052 36.214  1.000 36.465  0  260 GLY   B O   1 ? 
ATOM   2983 N  N   . LEU   C 1 151 ? -28.610 -22.992 34.994  1.000 33.124  0  261 LEU   B N   1 ? 
ATOM   2984 C  CA  . LEU   C 1 151 ? -28.191 -21.750 34.364  1.000 35.804  0  261 LEU   B CA  1 ? 
ATOM   2985 C  C   . LEU   C 1 151 ? -29.327 -21.178 33.510  1.000 38.170  0  261 LEU   B C   1 ? 
ATOM   2986 O  O   . LEU   C 1 151 ? -29.416 -19.965 33.341  1.000 41.225  0  261 LEU   B O   1 ? 
ATOM   2987 C  CB  . LEU   C 1 151 ? -26.931 -21.988 33.535  1.000 35.255  0  261 LEU   B CB  1 ? 
ATOM   2988 C  CG  . LEU   C 1 151 ? -25.671 -22.369 34.318  1.000 40.461  0  261 LEU   B CG  1 ? 
ATOM   2989 C  CD1 . LEU   C 1 151 ? -24.524 -22.634 33.362  1.000 47.171  0  261 LEU   B CD1 1 ? 
ATOM   2990 C  CD2 . LEU   C 1 151 ? -25.284 -21.300 35.330  1.000 42.497  0  261 LEU   B CD2 1 ? 
ATOM   2991 N  N   . ARG   C 1 152 ? -30.202 -22.058 32.991  1.000 36.995  0  262 ARG   B N   1 ? 
ATOM   2992 C  CA  . ARG   C 1 152 ? -31.317 -21.628 32.152  1.000 41.822  0  262 ARG   B CA  1 ? 
ATOM   2993 C  C   . ARG   C 1 152 ? -32.333 -20.813 32.963  1.000 38.942  0  262 ARG   B C   1 ? 
ATOM   2994 O  O   . ARG   C 1 152 ? -33.093 -20.044 32.387  1.000 43.868  0  262 ARG   B O   1 ? 
ATOM   2995 C  CB  . ARG   C 1 152 ? -32.011 -22.800 31.438  1.000 48.689  0  262 ARG   B CB  1 ? 
ATOM   2996 C  CG  . ARG   C 1 152 ? -31.449 -23.083 30.048  1.000 56.642  0  262 ARG   B CG  1 ? 
ATOM   2997 C  CD  . ARG   C 1 152 ? -32.431 -23.821 29.131  1.000 56.856  0  262 ARG   B CD  1 ? 
ATOM   2998 N  NE  . ARG   C 1 152 ? -32.284 -25.282 29.150  1.000 67.874  0  262 ARG   B NE  1 ? 
ATOM   2999 C  CZ  . ARG   C 1 152 ? -31.953 -26.026 28.084  1.000 70.048  0  262 ARG   B CZ  1 ? 
ATOM   3000 N  NH1 . ARG   C 1 152 ? -31.675 -25.444 26.928  1.000 74.692  0  262 ARG   B NH1 1 ? 
ATOM   3001 N  NH2 . ARG   C 1 152 ? -31.873 -27.341 28.188  1.000 68.606  0  262 ARG   B NH2 1 ? 
ATOM   3002 N  N   . THR   C 1 153 ? -32.332 -20.969 34.298  1.000 36.068  0  263 THR   B N   1 ? 
ATOM   3003 C  CA  . THR   C 1 153 ? -33.279 -20.243 35.146  1.000 40.693  0  263 THR   B CA  1 ? 
ATOM   3004 C  C   . THR   C 1 153 ? -32.794 -18.801 35.365  1.000 42.846  0  263 THR   B C   1 ? 
ATOM   3005 O  O   . THR   C 1 153 ? -33.546 -17.971 35.868  1.000 40.261  0  263 THR   B O   1 ? 
ATOM   3006 C  CB  . THR   C 1 153 ? -33.475 -20.974 36.478  1.000 41.203  0  263 THR   B CB  1 ? 
ATOM   3007 O  OG1 . THR   C 1 153 ? -32.213 -20.980 37.137  1.000 41.271  0  263 THR   B OG1 1 ? 
ATOM   3008 C  CG2 . THR   C 1 153 ? -33.978 -22.395 36.300  1.000 42.513  0  263 THR   B CG2 1 ? 
ATOM   3009 N  N   . LEU   C 1 154 ? -31.536 -18.516 34.979  1.000 40.135  0  264 LEU   B N   1 ? 
ATOM   3010 C  CA  . LEU   C 1 154 ? -30.912 -17.227 35.261  1.000 38.595  0  264 LEU   B CA  1 ? 
ATOM   3011 C  C   . LEU   C 1 154 ? -30.947 -16.313 34.029  1.000 40.084  0  264 LEU   B C   1 ? 
ATOM   3012 O  O   . LEU   C 1 154 ? -30.848 -15.097 34.167  1.000 42.240  0  264 LEU   B O   1 ? 
ATOM   3013 C  CB  . LEU   C 1 154 ? -29.475 -17.454 35.734  1.000 39.789  0  264 LEU   B CB  1 ? 
ATOM   3014 C  CG  . LEU   C 1 154 ? -29.305 -18.126 37.099  1.000 37.310  0  264 LEU   B CG  1 ? 
ATOM   3015 C  CD1 . LEU   C 1 154 ? -27.834 -18.351 37.382  1.000 36.922  0  264 LEU   B CD1 1 ? 
ATOM   3016 C  CD2 . LEU   C 1 154 ? -29.943 -17.311 38.212  1.000 34.316  0  264 LEU   B CD2 1 ? 
ATOM   3017 N  N   . VAL   C 1 155 ? -31.026 -16.904 32.829  1.000 46.264  0  265 VAL   B N   1 ? 
ATOM   3018 C  CA  . VAL   C 1 155 ? -30.900 -16.136 31.593  1.000 48.018  0  265 VAL   B CA  1 ? 
ATOM   3019 C  C   . VAL   C 1 155 ? -31.960 -15.030 31.588  1.000 49.033  0  265 VAL   B C   1 ? 
ATOM   3020 O  O   . VAL   C 1 155 ? -33.137 -15.295 31.832  1.000 51.497  0  265 VAL   B O   1 ? 
ATOM   3021 C  CB  . VAL   C 1 155 ? -31.002 -17.014 30.327  1.000 49.976  0  265 VAL   B CB  1 ? 
ATOM   3022 C  CG1 . VAL   C 1 155 ? -29.910 -18.076 30.287  1.000 43.797  0  265 VAL   B CG1 1 ? 
ATOM   3023 C  CG2 . VAL   C 1 155 ? -32.380 -17.655 30.173  1.000 60.582  0  265 VAL   B CG2 1 ? 
ATOM   3024 N  N   . PRO   C 1 156 ? -31.566 -13.750 31.348  1.000 60.994  0  266 PRO   B N   1 ? 
ATOM   3025 C  CA  . PRO   C 1 156 ? -32.522 -12.639 31.336  1.000 62.615  0  266 PRO   B CA  1 ? 
ATOM   3026 C  C   . PRO   C 1 156 ? -33.356 -12.585 30.056  1.000 56.301  0  266 PRO   B C   1 ? 
ATOM   3027 O  O   . PRO   C 1 156 ? -32.916 -13.186 29.053  1.000 48.773  0  266 PRO   B O   1 ? 
ATOM   3028 C  CB  . PRO   C 1 156 ? -31.602 -11.405 31.496  1.000 65.023  0  266 PRO   B CB  1 ? 
ATOM   3029 C  CG  . PRO   C 1 156 ? -30.303 -11.825 30.822  1.000 58.263  0  266 PRO   B CG  1 ? 
ATOM   3030 C  CD  . PRO   C 1 156 ? -30.181 -13.315 31.104  1.000 59.752  0  266 PRO   B CD  1 ? 
ATOM   3031 N  N   . PRO   D 1 30  ? -37.958 -44.203 -53.898 1.000 75.796  0  140 PRO   C N   1 ? 
ATOM   3032 C  CA  . PRO   D 1 30  ? -37.748 -45.515 -53.309 1.000 70.612  0  140 PRO   C CA  1 ? 
ATOM   3033 C  C   . PRO   D 1 30  ? -36.388 -46.151 -53.602 1.000 60.921  0  140 PRO   C C   1 ? 
ATOM   3034 O  O   . PRO   D 1 30  ? -35.944 -47.020 -52.855 1.000 63.027  0  140 PRO   C O   1 ? 
ATOM   3035 C  CB  . PRO   D 1 30  ? -38.909 -46.304 -53.918 1.000 72.307  0  140 PRO   C CB  1 ? 
ATOM   3036 C  CG  . PRO   D 1 30  ? -40.057 -45.324 -53.864 1.000 87.144  0  140 PRO   C CG  1 ? 
ATOM   3037 C  CD  . PRO   D 1 30  ? -39.394 -43.940 -53.956 1.000 89.316  0  140 PRO   C CD  1 ? 
ATOM   3038 N  N   . LYS   D 1 31  ? -35.748 -45.737 -54.712 1.000 52.382  0  141 LYS   C N   1 ? 
ATOM   3039 C  CA  . LYS   D 1 31  ? -34.406 -46.209 -55.042 1.000 48.581  0  141 LYS   C CA  1 ? 
ATOM   3040 C  C   . LYS   D 1 31  ? -33.383 -45.472 -54.182 1.000 38.623  0  141 LYS   C C   1 ? 
ATOM   3041 O  O   . LYS   D 1 31  ? -33.206 -44.264 -54.313 1.000 45.579  0  141 LYS   C O   1 ? 
ATOM   3042 C  CB  . LYS   D 1 31  ? -34.082 -46.088 -56.539 1.000 46.906  0  141 LYS   C CB  1 ? 
ATOM   3043 C  CG  . LYS   D 1 31  ? -34.133 -47.416 -57.294 1.000 52.729  0  141 LYS   C CG  1 ? 
ATOM   3044 C  CD  . LYS   D 1 31  ? -33.744 -47.348 -58.767 1.000 54.443  0  141 LYS   C CD  1 ? 
ATOM   3045 C  CE  . LYS   D 1 31  ? -34.869 -46.915 -59.650 1.000 62.047  0  141 LYS   C CE  1 ? 
ATOM   3046 N  NZ  . LYS   D 1 31  ? -34.500 -46.985 -61.066 1.000 66.210  0  141 LYS   C NZ  1 ? 
ATOM   3047 N  N   . ILE   D 1 32  ? -32.684 -46.236 -53.331 1.000 35.928  0  142 ILE   C N   1 ? 
ATOM   3048 C  CA  . ILE   D 1 32  ? -31.693 -45.684 -52.422 1.000 40.514  0  142 ILE   C CA  1 ? 
ATOM   3049 C  C   . ILE   D 1 32  ? -30.361 -45.569 -53.161 1.000 38.316  0  142 ILE   C C   1 ? 
ATOM   3050 O  O   . ILE   D 1 32  ? -29.423 -46.318 -52.889 1.000 45.267  0  142 ILE   C O   1 ? 
ATOM   3051 C  CB  . ILE   D 1 32  ? -31.574 -46.543 -51.143 1.000 37.369  0  142 ILE   C CB  1 ? 
ATOM   3052 C  CG1 . ILE   D 1 32  ? -32.948 -46.841 -50.525 1.000 38.805  0  142 ILE   C CG1 1 ? 
ATOM   3053 C  CG2 . ILE   D 1 32  ? -30.633 -45.890 -50.126 1.000 42.811  0  142 ILE   C CG2 1 ? 
ATOM   3054 C  CD1 . ILE   D 1 32  ? -33.745 -45.603 -50.149 1.000 38.461  0  142 ILE   C CD1 1 ? 
ATOM   3055 N  N   . THR   D 1 33  ? -30.300 -44.634 -54.112 1.000 41.682  0  143 THR   C N   1 ? 
ATOM   3056 C  CA  . THR   D 1 33  ? -29.054 -44.298 -54.782 1.000 43.051  0  143 THR   C CA  1 ? 
ATOM   3057 C  C   . THR   D 1 33  ? -28.186 -43.496 -53.814 1.000 36.620  0  143 THR   C C   1 ? 
ATOM   3058 O  O   . THR   D 1 33  ? -28.653 -43.082 -52.751 1.000 38.367  0  143 THR   C O   1 ? 
ATOM   3059 C  CB  . THR   D 1 33  ? -29.348 -43.517 -56.065 1.000 46.577  0  143 THR   C CB  1 ? 
ATOM   3060 O  OG1 . THR   D 1 33  ? -30.106 -42.382 -55.660 1.000 38.525  0  143 THR   C OG1 1 ? 
ATOM   3061 C  CG2 . THR   D 1 33  ? -30.133 -44.332 -57.080 1.000 46.980  0  143 THR   C CG2 1 ? 
ATOM   3062 N  N   . LEU   D 1 34  ? -26.926 -43.279 -54.192 1.000 39.963  0  144 LEU   C N   1 ? 
ATOM   3063 C  CA  . LEU   D 1 34  ? -26.009 -42.496 -53.377 1.000 44.938  0  144 LEU   C CA  1 ? 
ATOM   3064 C  C   . LEU   D 1 34  ? -26.528 -41.057 -53.275 1.000 37.682  0  144 LEU   C C   1 ? 
ATOM   3065 O  O   . LEU   D 1 34  ? -26.385 -40.418 -52.234 1.000 35.223  0  144 LEU   C O   1 ? 
ATOM   3066 C  CB  . LEU   D 1 34  ? -24.598 -42.556 -53.965 1.000 47.109  0  144 LEU   C CB  1 ? 
ATOM   3067 C  CG  . LEU   D 1 34  ? -23.496 -41.867 -53.149 1.000 63.395  0  144 LEU   C CG  1 ? 
ATOM   3068 C  CD1 . LEU   D 1 34  ? -23.340 -42.478 -51.768 1.000 65.810  0  144 LEU   C CD1 1 ? 
ATOM   3069 C  CD2 . LEU   D 1 34  ? -22.176 -41.907 -53.901 1.000 73.239  0  144 LEU   C CD2 1 ? 
ATOM   3070 N  N   . LEU   D 1 35  ? -27.195 -40.588 -54.345 1.000 37.902  0  145 LEU   C N   1 ? 
ATOM   3071 C  CA  . LEU   D 1 35  ? -27.754 -39.241 -54.388 1.000 40.717  0  145 LEU   C CA  1 ? 
ATOM   3072 C  C   . LEU   D 1 35  ? -28.933 -39.125 -53.412 1.000 38.995  0  145 LEU   C C   1 ? 
ATOM   3073 O  O   . LEU   D 1 35  ? -29.071 -38.114 -52.726 1.000 39.527  0  145 LEU   C O   1 ? 
ATOM   3074 C  CB  . LEU   D 1 35  ? -28.172 -38.898 -55.821 1.000 41.956  0  145 LEU   C CB  1 ? 
ATOM   3075 C  CG  . LEU   D 1 35  ? -28.826 -37.524 -56.026 1.000 44.095  0  145 LEU   C CG  1 ? 
ATOM   3076 C  CD1 . LEU   D 1 35  ? -27.951 -36.398 -55.484 1.000 42.203  0  145 LEU   C CD1 1 ? 
ATOM   3077 C  CD2 . LEU   D 1 35  ? -29.137 -37.291 -57.495 1.000 41.042  0  145 LEU   C CD2 1 ? 
ATOM   3078 N  N   . THR   D 1 36  ? -29.789 -40.159 -53.376 1.000 37.637  0  146 THR   C N   1 ? 
ATOM   3079 C  CA  . THR   D 1 36  ? -30.956 -40.166 -52.497 1.000 40.229  0  146 THR   C CA  1 ? 
ATOM   3080 C  C   . THR   D 1 36  ? -30.497 -40.138 -51.032 1.000 38.461  0  146 THR   C C   1 ? 
ATOM   3081 O  O   . THR   D 1 36  ? -31.117 -39.474 -50.203 1.000 37.973  0  146 THR   C O   1 ? 
ATOM   3082 C  CB  . THR   D 1 36  ? -31.835 -41.386 -52.794 1.000 43.598  0  146 THR   C CB  1 ? 
ATOM   3083 O  OG1 . THR   D 1 36  ? -32.325 -41.219 -54.119 1.000 45.533  0  146 THR   C OG1 1 ? 
ATOM   3084 C  CG2 . THR   D 1 36  ? -33.019 -41.497 -51.851 1.000 42.559  0  146 THR   C CG2 1 ? 
ATOM   3085 N  N   . LEU   D 1 37  ? -29.428 -40.891 -50.720 1.000 35.097  0  147 LEU   C N   1 ? 
ATOM   3086 C  CA  . LEU   D 1 37  ? -28.846 -40.887 -49.378 1.000 36.517  0  147 LEU   C CA  1 ? 
ATOM   3087 C  C   . LEU   D 1 37  ? -28.515 -39.454 -48.960 1.000 32.943  0  147 LEU   C C   1 ? 
ATOM   3088 O  O   . LEU   D 1 37  ? -28.805 -39.054 -47.835 1.000 37.150  0  147 LEU   C O   1 ? 
ATOM   3089 C  CB  . LEU   D 1 37  ? -27.598 -41.773 -49.310 1.000 41.303  0  147 LEU   C CB  1 ? 
ATOM   3090 C  CG  . LEU   D 1 37  ? -27.824 -43.256 -49.004 1.000 42.562  0  147 LEU   C CG  1 ? 
ATOM   3091 C  CD1 . LEU   D 1 37  ? -26.502 -43.999 -49.076 1.000 47.176  0  147 LEU   C CD1 1 ? 
ATOM   3092 C  CD2 . LEU   D 1 37  ? -28.468 -43.459 -47.641 1.000 44.839  0  147 LEU   C CD2 1 ? 
ATOM   3093 N  N   . ILE   D 1 38  ? -27.863 -38.710 -49.862 1.000 35.087  0  148 ILE   C N   1 ? 
ATOM   3094 C  CA  . ILE   D 1 38  ? -27.378 -37.370 -49.557 1.000 39.135  0  148 ILE   C CA  1 ? 
ATOM   3095 C  C   . ILE   D 1 38  ? -28.572 -36.443 -49.332 1.000 36.782  0  148 ILE   C C   1 ? 
ATOM   3096 O  O   . ILE   D 1 38  ? -28.610 -35.708 -48.349 1.000 35.096  0  148 ILE   C O   1 ? 
ATOM   3097 C  CB  . ILE   D 1 38  ? -26.451 -36.854 -50.674 1.000 43.313  0  148 ILE   C CB  1 ? 
ATOM   3098 C  CG1 . ILE   D 1 38  ? -25.230 -37.755 -50.851 1.000 44.098  0  148 ILE   C CG1 1 ? 
ATOM   3099 C  CG2 . ILE   D 1 38  ? -26.038 -35.404 -50.415 1.000 52.623  0  148 ILE   C CG2 1 ? 
ATOM   3100 C  CD1 . ILE   D 1 38  ? -24.458 -37.501 -52.129 1.000 48.056  0  148 ILE   C CD1 1 ? 
ATOM   3101 N  N   . LYS   D 1 39  ? -29.543 -36.494 -50.255 1.000 37.737  0  149 LYS   C N   1 ? 
ATOM   3102 C  CA  . LYS   D 1 39  ? -30.748 -35.679 -50.162 1.000 40.468  0  149 LYS   C CA  1 ? 
ATOM   3103 C  C   . LYS   D 1 39  ? -31.446 -35.929 -48.824 1.000 36.292  0  149 LYS   C C   1 ? 
ATOM   3104 O  O   . LYS   D 1 39  ? -31.930 -34.991 -48.195 1.000 39.999  0  149 LYS   C O   1 ? 
ATOM   3105 C  CB  . LYS   D 1 39  ? -31.697 -35.974 -51.329 1.000 45.624  0  149 LYS   C CB  1 ? 
ATOM   3106 C  CG  . LYS   D 1 39  ? -31.225 -35.468 -52.683 1.000 49.646  0  149 LYS   C CG  1 ? 
ATOM   3107 C  CD  . LYS   D 1 39  ? -32.126 -35.879 -53.841 1.000 52.714  0  149 LYS   C CD  1 ? 
ATOM   3108 C  CE  . LYS   D 1 39  ? -31.646 -35.342 -55.151 1.000 62.626  0  149 LYS   C CE  1 ? 
ATOM   3109 N  NZ  . LYS   D 1 39  ? -32.361 -35.944 -56.278 1.000 74.305  0  149 LYS   C NZ  1 ? 
ATOM   3110 N  N   . THR   D 1 40  ? -31.485 -37.203 -48.399 1.000 33.422  0  150 THR   C N   1 ? 
ATOM   3111 C  CA  . THR   D 1 40  ? -32.138 -37.583 -47.151 1.000 34.253  0  150 THR   C CA  1 ? 
ATOM   3112 C  C   . THR   D 1 40  ? -31.372 -36.979 -45.969 1.000 34.022  0  150 THR   C C   1 ? 
ATOM   3113 O  O   . THR   D 1 40  ? -31.975 -36.398 -45.067 1.000 31.395  0  150 THR   C O   1 ? 
ATOM   3114 C  CB  . THR   D 1 40  ? -32.227 -39.108 -47.057 1.000 35.731  0  150 THR   C CB  1 ? 
ATOM   3115 O  OG1 . THR   D 1 40  ? -32.980 -39.521 -48.197 1.000 35.215  0  150 THR   C OG1 1 ? 
ATOM   3116 C  CG2 . THR   D 1 40  ? -32.918 -39.577 -45.790 1.000 36.216  0  150 THR   C CG2 1 ? 
ATOM   3117 N  N   . ALA   D 1 41  ? -30.038 -37.083 -46.009 1.000 31.356  0  151 ALA   C N   1 ? 
ATOM   3118 C  CA  . ALA   D 1 41  ? -29.191 -36.541 -44.956 1.000 35.435  0  151 ALA   C CA  1 ? 
ATOM   3119 C  C   . ALA   D 1 41  ? -29.283 -35.012 -44.934 1.000 39.091  0  151 ALA   C C   1 ? 
ATOM   3120 O  O   . ALA   D 1 41  ? -29.262 -34.407 -43.862 1.000 43.666  0  151 ALA   C O   1 ? 
ATOM   3121 C  CB  . ALA   D 1 41  ? -27.771 -37.008 -45.145 1.000 34.898  0  151 ALA   C CB  1 ? 
ATOM   3122 N  N   . GLU   D 1 42  ? -29.358 -34.397 -46.129 1.000 36.567  0  152 GLU   C N   1 ? 
ATOM   3123 C  CA  . GLU   D 1 42  ? -29.545 -32.952 -46.246 1.000 37.078  0  152 GLU   C CA  1 ? 
ATOM   3124 C  C   . GLU   D 1 42  ? -30.801 -32.537 -45.479 1.000 39.028  0  152 GLU   C C   1 ? 
ATOM   3125 O  O   . GLU   D 1 42  ? -30.771 -31.586 -44.702 1.000 40.658  0  152 GLU   C O   1 ? 
ATOM   3126 C  CB  . GLU   D 1 42  ? -29.662 -32.509 -47.709 1.000 41.023  0  152 GLU   C CB  1 ? 
ATOM   3127 C  CG  . GLU   D 1 42  ? -28.320 -32.370 -48.427 1.000 50.773  0  152 GLU   C CG  1 ? 
ATOM   3128 C  CD  . GLU   D 1 42  ? -28.428 -31.958 -49.896 1.000 53.893  0  152 GLU   C CD  1 ? 
ATOM   3129 O  OE1 . GLU   D 1 42  ? -29.559 -31.936 -50.433 1.000 57.513  0  152 GLU   C OE1 1 ? 
ATOM   3130 O  OE2 . GLU   D 1 42  ? -27.382 -31.624 -50.492 1.000 54.044  0  152 GLU   C OE2 1 ? 
ATOM   3131 N  N   . HIS   D 1 43  ? -31.892 -33.285 -45.692 1.000 37.092  0  153 HIS   C N   1 ? 
ATOM   3132 C  CA  . HIS   D 1 43  ? -33.184 -32.965 -45.107 1.000 38.549  0  153 HIS   C CA  1 ? 
ATOM   3133 C  C   . HIS   D 1 43  ? -33.123 -33.080 -43.581 1.000 38.854  0  153 HIS   C C   1 ? 
ATOM   3134 O  O   . HIS   D 1 43  ? -33.453 -32.128 -42.877 1.000 43.808  0  153 HIS   C O   1 ? 
ATOM   3135 C  CB  . HIS   D 1 43  ? -34.280 -33.852 -45.715 1.000 40.367  0  153 HIS   C CB  1 ? 
ATOM   3136 C  CG  . HIS   D 1 43  ? -35.640 -33.616 -45.147 1.000 44.664  0  153 HIS   C CG  1 ? 
ATOM   3137 N  ND1 . HIS   D 1 43  ? -36.414 -32.530 -45.494 1.000 54.518  0  153 HIS   C ND1 1 ? 
ATOM   3138 C  CD2 . HIS   D 1 43  ? -36.342 -34.290 -44.224 1.000 44.828  0  153 HIS   C CD2 1 ? 
ATOM   3139 C  CE1 . HIS   D 1 43  ? -37.555 -32.575 -44.822 1.000 55.204  0  153 HIS   C CE1 1 ? 
ATOM   3140 N  NE2 . HIS   D 1 43  ? -37.537 -33.638 -44.052 1.000 50.180  0  153 HIS   C NE2 1 ? 
ATOM   3141 N  N   . TRP   D 1 44  ? -32.659 -34.239 -43.082 1.000 36.583  0  154 TRP   C N   1 ? 
ATOM   3142 C  CA  . TRP   D 1 44  ? -32.741 -34.551 -41.656 1.000 39.015  0  154 TRP   C CA  1 ? 
ATOM   3143 C  C   . TRP   D 1 44  ? -31.658 -33.826 -40.851 1.000 38.441  0  154 TRP   C C   1 ? 
ATOM   3144 O  O   . TRP   D 1 44  ? -31.755 -33.748 -39.630 1.000 46.506  0  154 TRP   C O   1 ? 
ATOM   3145 C  CB  . TRP   D 1 44  ? -32.686 -36.065 -41.433 1.000 35.699  0  154 TRP   C CB  1 ? 
ATOM   3146 C  CG  . TRP   D 1 44  ? -33.940 -36.766 -41.872 1.000 32.557  0  154 TRP   C CG  1 ? 
ATOM   3147 C  CD1 . TRP   D 1 44  ? -34.151 -37.412 -43.053 1.000 35.459  0  154 TRP   C CD1 1 ? 
ATOM   3148 C  CD2 . TRP   D 1 44  ? -35.199 -36.790 -41.172 1.000 35.991  0  154 TRP   C CD2 1 ? 
ATOM   3149 N  NE1 . TRP   D 1 44  ? -35.436 -37.879 -43.117 1.000 39.338  0  154 TRP   C NE1 1 ? 
ATOM   3150 C  CE2 . TRP   D 1 44  ? -36.107 -37.505 -41.985 1.000 35.244  0  154 TRP   C CE2 1 ? 
ATOM   3151 C  CE3 . TRP   D 1 44  ? -35.644 -36.291 -39.940 1.000 38.659  0  154 TRP   C CE3 1 ? 
ATOM   3152 C  CZ2 . TRP   D 1 44  ? -37.428 -37.729 -41.606 1.000 33.906  0  154 TRP   C CZ2 1 ? 
ATOM   3153 C  CZ3 . TRP   D 1 44  ? -36.955 -36.510 -39.569 1.000 38.648  0  154 TRP   C CZ3 1 ? 
ATOM   3154 C  CH2 . TRP   D 1 44  ? -37.835 -37.214 -40.395 1.000 36.021  0  154 TRP   C CH2 1 ? 
ATOM   3155 N  N   . ALA   D 1 45  ? -30.647 -33.277 -41.540 1.000 37.765  0  155 ALA   C N   1 ? 
ATOM   3156 C  CA  . ALA   D 1 45  ? -29.634 -32.449 -40.888 1.000 39.523  0  155 ALA   C CA  1 ? 
ATOM   3157 C  C   . ALA   D 1 45  ? -30.253 -31.127 -40.413 1.000 44.467  0  155 ALA   C C   1 ? 
ATOM   3158 O  O   . ALA   D 1 45  ? -29.754 -30.512 -39.477 1.000 49.700  0  155 ALA   C O   1 ? 
ATOM   3159 C  CB  . ALA   D 1 45  ? -28.475 -32.203 -41.833 1.000 33.075  0  155 ALA   C CB  1 ? 
ATOM   3160 N  N   . ARG   D 1 46  ? -31.332 -30.695 -41.090 1.000 48.381  0  156 ARG   C N   1 ? 
ATOM   3161 C  CA  . ARG   D 1 46  ? -31.988 -29.422 -40.803 1.000 52.900  0  156 ARG   C CA  1 ? 
ATOM   3162 C  C   . ARG   D 1 46  ? -33.083 -29.599 -39.745 1.000 61.779  0  156 ARG   C C   1 ? 
ATOM   3163 O  O   . ARG   D 1 46  ? -33.500 -28.623 -39.123 1.000 66.179  0  156 ARG   C O   1 ? 
ATOM   3164 C  CB  . ARG   D 1 46  ? -32.601 -28.856 -42.091 1.000 51.252  0  156 ARG   C CB  1 ? 
ATOM   3165 C  CG  . ARG   D 1 46  ? -31.609 -28.191 -43.035 1.000 56.787  0  156 ARG   C CG  1 ? 
ATOM   3166 C  CD  . ARG   D 1 46  ? -31.999 -28.376 -44.503 1.000 68.190  0  156 ARG   C CD  1 ? 
ATOM   3167 N  NE  . ARG   D 1 46  ? -33.417 -28.099 -44.771 1.000 72.418  0  156 ARG   C NE  1 ? 
ATOM   3168 C  CZ  . ARG   D 1 46  ? -34.076 -28.488 -45.870 1.000 91.582  0  156 ARG   C CZ  1 ? 
ATOM   3169 N  NH1 . ARG   D 1 46  ? -33.464 -29.220 -46.792 1.000 98.271  0  156 ARG   C NH1 1 ? 
ATOM   3170 N  NH2 . ARG   D 1 46  ? -35.357 -28.185 -46.018 1.000 94.577  0  156 ARG   C NH2 1 ? 
ATOM   3171 N  N   . GLN   D 1 47  ? -33.541 -30.848 -39.549 1.000 56.043  0  157 GLN   C N   1 ? 
ATOM   3172 C  CA  . GLN   D 1 47  ? -34.729 -31.117 -38.746 1.000 52.052  0  157 GLN   C CA  1 ? 
ATOM   3173 C  C   . GLN   D 1 47  ? -34.383 -31.135 -37.256 1.000 56.369  0  157 GLN   C C   1 ? 
ATOM   3174 O  O   . GLN   D 1 47  ? -33.264 -31.476 -36.868 1.000 50.341  0  157 GLN   C O   1 ? 
ATOM   3175 C  CB  . GLN   D 1 47  ? -35.358 -32.459 -39.124 1.000 53.171  0  157 GLN   C CB  1 ? 
ATOM   3176 C  CG  . GLN   D 1 47  ? -35.734 -32.587 -40.596 1.000 51.897  0  157 GLN   C CG  1 ? 
ATOM   3177 C  CD  . GLN   D 1 47  ? -36.705 -31.528 -41.066 1.000 51.296  0  157 GLN   C CD  1 ? 
ATOM   3178 O  OE1 . GLN   D 1 47  ? -36.458 -30.819 -42.049 1.000 53.662  0  157 GLN   C OE1 1 ? 
ATOM   3179 N  NE2 . GLN   D 1 47  ? -37.844 -31.439 -40.392 1.000 47.139  0  157 GLN   C NE2 1 ? 
ATOM   3180 N  N   . ASP   D 1 48  ? -35.374 -30.756 -36.433 1.000 57.721  0  158 ASP   C N   1 ? 
ATOM   3181 C  CA  . ASP   D 1 48  ? -35.327 -30.961 -34.995 1.000 65.344  0  158 ASP   C CA  1 ? 
ATOM   3182 C  C   . ASP   D 1 48  ? -35.913 -32.338 -34.695 1.000 60.121  0  158 ASP   C C   1 ? 
ATOM   3183 O  O   . ASP   D 1 48  ? -37.094 -32.573 -34.938 1.000 60.662  0  158 ASP   C O   1 ? 
ATOM   3184 C  CB  . ASP   D 1 48  ? -36.086 -29.867 -34.258 1.000 76.324  0  158 ASP   C CB  1 ? 
ATOM   3185 C  CG  . ASP   D 1 48  ? -36.303 -30.112 -32.772 1.000 80.742  0  158 ASP   C CG  1 ? 
ATOM   3186 O  OD1 . ASP   D 1 48  ? -35.296 -30.189 -32.037 1.000 87.526  0  158 ASP   C OD1 1 ? 
ATOM   3187 O  OD2 . ASP   D 1 48  ? -37.475 -30.269 -32.370 1.000 80.899  0  158 ASP   C OD2 1 ? 
ATOM   3188 N  N   . ILE   D 1 49  ? -35.081 -33.235 -34.146 1.000 63.062  0  159 ILE   C N   1 ? 
ATOM   3189 C  CA  . ILE   D 1 49  ? -35.452 -34.638 -34.009 1.000 60.398  0  159 ILE   C CA  1 ? 
ATOM   3190 C  C   . ILE   D 1 49  ? -35.558 -35.020 -32.529 1.000 65.303  0  159 ILE   C C   1 ? 
ATOM   3191 O  O   . ILE   D 1 49  ? -35.485 -36.204 -32.193 1.000 68.469  0  159 ILE   C O   1 ? 
ATOM   3192 C  CB  . ILE   D 1 49  ? -34.450 -35.542 -34.758 1.000 55.765  0  159 ILE   C CB  1 ? 
ATOM   3193 C  CG1 . ILE   D 1 49  ? -33.024 -35.414 -34.185 1.000 48.550  0  159 ILE   C CG1 1 ? 
ATOM   3194 C  CG2 . ILE   D 1 49  ? -34.485 -35.257 -36.263 1.000 56.063  0  159 ILE   C CG2 1 ? 
ATOM   3195 C  CD1 . ILE   D 1 49  ? -32.062 -36.487 -34.662 1.000 48.620  0  159 ILE   C CD1 1 ? 
ATOM   3196 N  N   . ARG   D 1 50  ? -35.815 -34.030 -31.659 1.000 61.104  0  160 ARG   C N   1 ? 
ATOM   3197 C  CA  . ARG   D 1 50  ? -35.913 -34.290 -30.229 1.000 64.631  0  160 ARG   C CA  1 ? 
ATOM   3198 C  C   . ARG   D 1 50  ? -37.300 -34.863 -29.899 1.000 60.067  0  160 ARG   C C   1 ? 
ATOM   3199 O  O   . ARG   D 1 50  ? -37.483 -35.446 -28.837 1.000 62.780  0  160 ARG   C O   1 ? 
ATOM   3200 C  CB  . ARG   D 1 50  ? -35.588 -33.042 -29.390 1.000 71.479  0  160 ARG   C CB  1 ? 
ATOM   3201 C  CG  . ARG   D 1 50  ? -36.670 -31.970 -29.333 1.000 85.226  0  160 ARG   C CG  1 ? 
ATOM   3202 C  CD  . ARG   D 1 50  ? -36.397 -30.935 -28.230 1.000 90.170  0  160 ARG   C CD  1 ? 
ATOM   3203 N  NE  . ARG   D 1 50  ? -35.322 -29.989 -28.561 1.000 84.264  0  160 ARG   C NE  1 ? 
ATOM   3204 C  CZ  . ARG   D 1 50  ? -35.448 -28.928 -29.365 1.000 90.505  0  160 ARG   C CZ  1 ? 
ATOM   3205 N  NH1 . ARG   D 1 50  ? -36.627 -28.616 -29.885 1.000 87.382  0  160 ARG   C NH1 1 ? 
ATOM   3206 N  NH2 . ARG   D 1 50  ? -34.401 -28.156 -29.610 1.000 87.910  0  160 ARG   C NH2 1 ? 
ATOM   3207 N  N   . THR   D 1 51  ? -38.258 -34.730 -30.844 1.000 70.940  0  161 THR   C N   1 ? 
ATOM   3208 C  CA  . THR   D 1 51  ? -39.631 -35.196 -30.636 1.000 71.502  0  161 THR   C CA  1 ? 
ATOM   3209 C  C   . THR   D 1 51  ? -39.966 -36.322 -31.625 1.000 74.151  0  161 THR   C C   1 ? 
ATOM   3210 O  O   . THR   D 1 51  ? -41.133 -36.685 -31.773 1.000 68.756  0  161 THR   C O   1 ? 
ATOM   3211 C  CB  . THR   D 1 51  ? -40.602 -34.021 -30.797 1.000 71.254  0  161 THR   C CB  1 ? 
ATOM   3212 O  OG1 . THR   D 1 51  ? -40.499 -33.604 -32.156 1.000 74.913  0  161 THR   C OG1 1 ? 
ATOM   3213 C  CG2 . THR   D 1 51  ? -40.284 -32.861 -29.872 1.000 72.117  0  161 THR   C CG2 1 ? 
ATOM   3214 N  N   . ILE   D 1 52  ? -38.934 -36.877 -32.282 1.000 75.556  0  162 ILE   C N   1 ? 
ATOM   3215 C  CA  . ILE   D 1 52  ? -39.124 -37.886 -33.320 1.000 65.425  0  162 ILE   C CA  1 ? 
ATOM   3216 C  C   . ILE   D 1 52  ? -39.478 -39.227 -32.672 1.000 56.585  0  162 ILE   C C   1 ? 
ATOM   3217 O  O   . ILE   D 1 52  ? -38.979 -39.560 -31.599 1.000 52.302  0  162 ILE   C O   1 ? 
ATOM   3218 C  CB  . ILE   D 1 52  ? -37.869 -37.981 -34.222 1.000 69.535  0  162 ILE   C CB  1 ? 
ATOM   3219 C  CG1 . ILE   D 1 52  ? -37.815 -36.822 -35.225 1.000 82.936  0  162 ILE   C CG1 1 ? 
ATOM   3220 C  CG2 . ILE   D 1 52  ? -37.781 -39.332 -34.933 1.000 66.503  0  162 ILE   C CG2 1 ? 
ATOM   3221 C  CD1 . ILE   D 1 52  ? -38.922 -36.840 -36.270 1.000 87.006  0  162 ILE   C CD1 1 ? 
ATOM   3222 N  N   . GLU   D 1 53  ? -40.369 -39.972 -33.341 1.000 49.514  0  163 GLU   C N   1 ? 
ATOM   3223 C  CA  . GLU   D 1 53  ? -40.757 -41.310 -32.916 1.000 49.688  0  163 GLU   C CA  1 ? 
ATOM   3224 C  C   . GLU   D 1 53  ? -39.557 -42.255 -33.050 1.000 48.784  0  163 GLU   C C   1 ? 
ATOM   3225 O  O   . GLU   D 1 53  ? -38.716 -42.080 -33.930 1.000 48.534  0  163 GLU   C O   1 ? 
ATOM   3226 C  CB  . GLU   D 1 53  ? -41.969 -41.812 -33.715 1.000 55.109  0  163 GLU   C CB  1 ? 
ATOM   3227 C  CG  . GLU   D 1 53  ? -41.805 -41.739 -35.237 1.000 64.166  0  163 GLU   C CG  1 ? 
ATOM   3228 C  CD  . GLU   D 1 53  ? -42.084 -40.374 -35.859 1.000 78.872  0  163 GLU   C CD  1 ? 
ATOM   3229 O  OE1 . GLU   D 1 53  ? -41.349 -39.410 -35.546 1.000 73.657  0  163 GLU   C OE1 1 ? 
ATOM   3230 O  OE2 . GLU   D 1 53  ? -43.048 -40.274 -36.650 1.000 90.971  0  163 GLU   C OE2 1 ? 
ATOM   3231 N  N   . ASP   D 1 54  ? -39.530 -43.295 -32.202 1.000 47.784  0  164 ASP   C N   1 ? 
ATOM   3232 C  CA  . ASP   D 1 54  ? -38.392 -44.205 -32.113 1.000 48.681  0  164 ASP   C CA  1 ? 
ATOM   3233 C  C   . ASP   D 1 54  ? -38.099 -44.854 -33.472 1.000 44.263  0  164 ASP   C C   1 ? 
ATOM   3234 O  O   . ASP   D 1 54  ? -36.943 -45.130 -33.784 1.000 41.274  0  164 ASP   C O   1 ? 
ATOM   3235 C  CB  . ASP   D 1 54  ? -38.600 -45.261 -31.036 1.000 47.404  0  164 ASP   C CB  1 ? 
ATOM   3236 C  CG  . ASP   D 1 54  ? -38.450 -44.776 -29.599 1.000 53.958  0  164 ASP   C CG  1 ? 
ATOM   3237 O  OD1 . ASP   D 1 54  ? -37.450 -44.074 -29.316 1.000 51.605  0  164 ASP   C OD1 1 ? 
ATOM   3238 O  OD2 . ASP   D 1 54  ? -39.271 -45.189 -28.757 1.000 56.150  0  164 ASP   C OD2 1 ? 
ATOM   3239 N  N   . SER   D 1 55  ? -39.154 -45.120 -34.259 1.000 43.139  0  165 SER   C N   1 ? 
ATOM   3240 C  CA  . SER   D 1 55  ? -39.014 -45.830 -35.528 1.000 47.786  0  165 SER   C CA  1 ? 
ATOM   3241 C  C   . SER   D 1 55  ? -38.111 -45.050 -36.492 1.000 42.268  0  165 SER   C C   1 ? 
ATOM   3242 O  O   . SER   D 1 55  ? -37.253 -45.637 -37.147 1.000 39.177  0  165 SER   C O   1 ? 
ATOM   3243 C  CB  . SER   D 1 55  ? -40.361 -46.113 -36.151 1.000 50.124  0  165 SER   C CB  1 ? 
ATOM   3244 O  OG  . SER   D 1 55  ? -41.058 -44.907 -36.432 1.000 61.299  0  165 SER   C OG  1 ? 
ATOM   3245 N  N   . LYS   D 1 56  ? -38.325 -43.728 -36.585 1.000 40.657  0  166 LYS   C N   1 ? 
ATOM   3246 C  CA  . LYS   D 1 56  ? -37.556 -42.892 -37.500 1.000 41.660  0  166 LYS   C CA  1 ? 
ATOM   3247 C  C   . LYS   D 1 56  ? -36.165 -42.625 -36.924 1.000 33.857  0  166 LYS   C C   1 ? 
ATOM   3248 O  O   . LYS   D 1 56  ? -35.186 -42.596 -37.662 1.000 38.909  0  166 LYS   C O   1 ? 
ATOM   3249 C  CB  . LYS   D 1 56  ? -38.267 -41.575 -37.826 1.000 47.596  0  166 LYS   C CB  1 ? 
ATOM   3250 C  CG  . LYS   D 1 56  ? -39.555 -41.709 -38.622 1.000 50.750  0  166 LYS   C CG  1 ? 
ATOM   3251 C  CD  . LYS   D 1 56  ? -39.855 -40.495 -39.497 1.000 58.697  0  166 LYS   C CD  1 ? 
ATOM   3252 C  CE  . LYS   D 1 56  ? -41.270 -40.449 -39.984 1.000 64.633  0  166 LYS   C CE  1 ? 
ATOM   3253 N  NZ  . LYS   D 1 56  ? -41.663 -41.678 -40.681 1.000 74.841  0  166 LYS   C NZ  1 ? 
ATOM   3254 N  N   . LEU   D 1 57  ? -36.087 -42.429 -35.604 1.000 33.648  0  167 LEU   C N   1 ? 
ATOM   3255 C  CA  . LEU   D 1 57  ? -34.808 -42.221 -34.935 1.000 34.081  0  167 LEU   C CA  1 ? 
ATOM   3256 C  C   . LEU   D 1 57  ? -33.904 -43.433 -35.178 1.000 33.487  0  167 LEU   C C   1 ? 
ATOM   3257 O  O   . LEU   D 1 57  ? -32.692 -43.286 -35.309 1.000 31.348  0  167 LEU   C O   1 ? 
ATOM   3258 C  CB  . LEU   D 1 57  ? -35.021 -41.972 -33.441 1.000 36.212  0  167 LEU   C CB  1 ? 
ATOM   3259 C  CG  . LEU   D 1 57  ? -33.755 -41.700 -32.615 1.000 40.168  0  167 LEU   C CG  1 ? 
ATOM   3260 C  CD1 . LEU   D 1 57  ? -33.030 -40.459 -33.103 1.000 42.520  0  167 LEU   C CD1 1 ? 
ATOM   3261 C  CD2 . LEU   D 1 57  ? -34.083 -41.574 -31.138 1.000 41.653  0  167 LEU   C CD2 1 ? 
ATOM   3262 N  N   . ARG   D 1 58  ? -34.514 -44.628 -35.230 1.000 32.861  0  168 ARG   C N   1 ? 
ATOM   3263 C  CA  . ARG   D 1 58  ? -33.779 -45.862 -35.467 1.000 31.687  0  168 ARG   C CA  1 ? 
ATOM   3264 C  C   . ARG   D 1 58  ? -33.322 -45.925 -36.925 1.000 28.380  0  168 ARG   C C   1 ? 
ATOM   3265 O  O   . ARG   D 1 58  ? -32.250 -46.450 -37.216 1.000 28.578  0  168 ARG   C O   1 ? 
ATOM   3266 C  CB  . ARG   D 1 58  ? -34.639 -47.087 -35.133 1.000 30.907  0  168 ARG   C CB  1 ? 
ATOM   3267 C  CG  . ARG   D 1 58  ? -33.929 -48.422 -35.322 1.000 28.187  0  168 ARG   C CG  1 ? 
ATOM   3268 C  CD  . ARG   D 1 58  ? -32.783 -48.605 -34.329 1.000 29.753  0  168 ARG   C CD  1 ? 
ATOM   3269 N  NE  . ARG   D 1 58  ? -32.054 -49.866 -34.513 1.000 30.841  0  168 ARG   C NE  1 ? 
ATOM   3270 C  CZ  . ARG   D 1 58  ? -31.226 -50.144 -35.531 1.000 32.043  0  168 ARG   C CZ  1 ? 
ATOM   3271 N  NH1 . ARG   D 1 58  ? -30.980 -49.238 -36.468 1.000 27.490  0  168 ARG   C NH1 1 ? 
ATOM   3272 N  NH2 . ARG   D 1 58  ? -30.626 -51.320 -35.588 1.000 32.243  0  168 ARG   C NH2 1 ? 
ATOM   3273 N  N   . ALA   D 1 59  ? -34.183 -45.450 -37.840 1.000 30.855  0  169 ALA   C N   1 ? 
ATOM   3274 C  CA  . ALA   D 1 59  ? -33.859 -45.418 -39.261 1.000 28.208  0  169 ALA   C CA  1 ? 
ATOM   3275 C  C   . ALA   D 1 59  ? -32.724 -44.422 -39.517 1.000 29.986  0  169 ALA   C C   1 ? 
ATOM   3276 O  O   . ALA   D 1 59  ? -31.852 -44.677 -40.341 1.000 33.469  0  169 ALA   C O   1 ? 
ATOM   3277 C  CB  . ALA   D 1 59  ? -35.092 -45.076 -40.069 1.000 26.918  0  169 ALA   C CB  1 ? 
ATOM   3278 N  N   . LEU   D 1 60  ? -32.744 -43.290 -38.790 1.000 29.879  0  170 LEU   C N   1 ? 
ATOM   3279 C  CA  . LEU   D 1 60  ? -31.695 -42.280 -38.896 1.000 33.482  0  170 LEU   C CA  1 ? 
ATOM   3280 C  C   . LEU   D 1 60  ? -30.352 -42.865 -38.443 1.000 34.746  0  170 LEU   C C   1 ? 
ATOM   3281 O  O   . LEU   D 1 60  ? -29.305 -42.469 -38.952 1.000 32.200  0  170 LEU   C O   1 ? 
ATOM   3282 C  CB  . LEU   D 1 60  ? -32.065 -41.036 -38.085 1.000 38.348  0  170 LEU   C CB  1 ? 
ATOM   3283 C  CG  . LEU   D 1 60  ? -33.043 -40.062 -38.753 1.000 38.751  0  170 LEU   C CG  1 ? 
ATOM   3284 C  CD1 . LEU   D 1 60  ? -33.593 -39.077 -37.753 1.000 39.251  0  170 LEU   C CD1 1 ? 
ATOM   3285 C  CD2 . LEU   D 1 60  ? -32.370 -39.327 -39.898 1.000 40.912  0  170 LEU   C CD2 1 ? 
ATOM   3286 N  N   . LEU   D 1 61  ? -30.389 -43.780 -37.461 1.000 30.482  0  171 LEU   C N   1 ? 
ATOM   3287 C  CA  . LEU   D 1 61  ? -29.180 -44.452 -36.997 1.000 33.690  0  171 LEU   C CA  1 ? 
ATOM   3288 C  C   . LEU   D 1 61  ? -28.613 -45.313 -38.128 1.000 33.012  0  171 LEU   C C   1 ? 
ATOM   3289 O  O   . LEU   D 1 61  ? -27.398 -45.368 -38.323 1.000 34.013  0  171 LEU   C O   1 ? 
ATOM   3290 C  CB  . LEU   D 1 61  ? -29.463 -45.284 -35.746 1.000 32.662  0  171 LEU   C CB  1 ? 
ATOM   3291 C  CG  . LEU   D 1 61  ? -28.274 -46.064 -35.170 1.000 34.103  0  171 LEU   C CG  1 ? 
ATOM   3292 C  CD1 . LEU   D 1 61  ? -27.102 -45.150 -34.829 1.000 35.843  0  171 LEU   C CD1 1 ? 
ATOM   3293 C  CD2 . LEU   D 1 61  ? -28.703 -46.847 -33.950 1.000 33.644  0  171 LEU   C CD2 1 ? 
ATOM   3294 N  N   . THR   D 1 62  ? -29.511 -45.977 -38.870 1.000 31.921  0  172 THR   C N   1 ? 
ATOM   3295 C  CA  . THR   D 1 62  ? -29.123 -46.794 -40.010 1.000 29.052  0  172 THR   C CA  1 ? 
ATOM   3296 C  C   . THR   D 1 62  ? -28.507 -45.894 -41.081 1.000 26.878  0  172 THR   C C   1 ? 
ATOM   3297 O  O   . THR   D 1 62  ? -27.507 -46.251 -41.694 1.000 29.497  0  172 THR   C O   1 ? 
ATOM   3298 C  CB  . THR   D 1 62  ? -30.344 -47.552 -40.534 1.000 32.965  0  172 THR   C CB  1 ? 
ATOM   3299 O  OG1 . THR   D 1 62  ? -30.850 -48.261 -39.410 1.000 41.294  0  172 THR   C OG1 1 ? 
ATOM   3300 C  CG2 . THR   D 1 62  ? -30.004 -48.523 -41.650 1.000 36.299  0  172 THR   C CG2 1 ? 
ATOM   3301 N  N   . LEU   D 1 63  ? -29.114 -44.713 -41.278 1.000 29.586  0  173 LEU   C N   1 ? 
ATOM   3302 C  CA  . LEU   D 1 63  ? -28.635 -43.741 -42.247 1.000 30.450  0  173 LEU   C CA  1 ? 
ATOM   3303 C  C   . LEU   D 1 63  ? -27.204 -43.334 -41.905 1.000 31.073  0  173 LEU   C C   1 ? 
ATOM   3304 O  O   . LEU   D 1 63  ? -26.357 -43.257 -42.787 1.000 35.845  0  173 LEU   C O   1 ? 
ATOM   3305 C  CB  . LEU   D 1 63  ? -29.572 -42.533 -42.270 1.000 33.571  0  173 LEU   C CB  1 ? 
ATOM   3306 C  CG  . LEU   D 1 63  ? -29.173 -41.386 -43.206 1.000 34.616  0  173 LEU   C CG  1 ? 
ATOM   3307 C  CD1 . LEU   D 1 63  ? -29.129 -41.844 -44.645 1.000 32.970  0  173 LEU   C CD1 1 ? 
ATOM   3308 C  CD2 . LEU   D 1 63  ? -30.120 -40.210 -43.047 1.000 39.169  0  173 LEU   C CD2 1 ? 
ATOM   3309 N  N   . CYS   D 1 64  ? -26.953 -43.078 -40.613 1.000 31.821  0  174 CYS   C N   1 ? 
ATOM   3310 C  CA  . CYS   D 1 64  ? -25.632 -42.684 -40.145 1.000 37.749  0  174 CYS   C CA  1 ? 
ATOM   3311 C  C   . CYS   D 1 64  ? -24.622 -43.795 -40.423 1.000 32.900  0  174 CYS   C C   1 ? 
ATOM   3312 O  O   . CYS   D 1 64  ? -23.511 -43.524 -40.872 1.000 35.304  0  174 CYS   C O   1 ? 
ATOM   3313 C  CB  . CYS   D 1 64  ? -25.652 -42.332 -38.660 1.000 40.830  0  174 CYS   C CB  1 ? 
ATOM   3314 S  SG  . CYS   D 1 64  ? -26.602 -40.834 -38.288 1.000 47.314  0  174 CYS   C SG  1 ? 
ATOM   3315 N  N   . ALA   D 1 65  ? -25.027 -45.045 -40.158 1.000 32.151  0  175 ALA   C N   1 ? 
ATOM   3316 C  CA  . ALA   D 1 65  ? -24.155 -46.197 -40.340 1.000 29.535  0  175 ALA   C CA  1 ? 
ATOM   3317 C  C   . ALA   D 1 65  ? -23.813 -46.365 -41.818 1.000 29.778  0  175 ALA   C C   1 ? 
ATOM   3318 O  O   . ALA   D 1 65  ? -22.645 -46.522 -42.173 1.000 30.053  0  175 ALA   C O   1 ? 
ATOM   3319 C  CB  . ALA   D 1 65  ? -24.815 -47.437 -39.781 1.000 30.369  0  175 ALA   C CB  1 ? 
ATOM   3320 N  N   . VAL   D 1 66  ? -24.848 -46.316 -42.671 1.000 27.824  0  176 VAL   C N   1 ? 
ATOM   3321 C  CA  . VAL   D 1 66  ? -24.679 -46.491 -44.106 1.000 28.114  0  176 VAL   C CA  1 ? 
ATOM   3322 C  C   . VAL   D 1 66  ? -23.746 -45.405 -44.644 1.000 35.577  0  176 VAL   C C   1 ? 
ATOM   3323 O  O   . VAL   D 1 66  ? -22.795 -45.706 -45.366 1.000 35.642  0  176 VAL   C O   1 ? 
ATOM   3324 C  CB  . VAL   D 1 66  ? -26.036 -46.478 -44.837 1.000 30.803  0  176 VAL   C CB  1 ? 
ATOM   3325 C  CG1 . VAL   D 1 66  ? -25.877 -46.266 -46.341 1.000 29.221  0  176 VAL   C CG1 1 ? 
ATOM   3326 C  CG2 . VAL   D 1 66  ? -26.839 -47.745 -44.553 1.000 31.864  0  176 VAL   C CG2 1 ? 
ATOM   3327 N  N   . MET   D 1 67  ? -24.025 -44.144 -44.278 1.000 35.896  0  177 MET   C N   1 ? 
ATOM   3328 C  CA  . MET   D 1 67  ? -23.252 -43.010 -44.766 1.000 39.030  0  177 MET   C CA  1 ? 
ATOM   3329 C  C   . MET   D 1 67  ? -21.809 -43.079 -44.256 1.000 38.013  0  177 MET   C C   1 ? 
ATOM   3330 O  O   . MET   D 1 67  ? -20.888 -42.690 -44.967 1.000 37.188  0  177 MET   C O   1 ? 
ATOM   3331 C  CB  . MET   D 1 67  ? -23.887 -41.684 -44.350 1.000 38.328  0  177 MET   C CB  1 ? 
ATOM   3332 C  CG  . MET   D 1 67  ? -25.137 -41.343 -45.128 1.000 45.936  0  177 MET   C CG  1 ? 
ATOM   3333 S  SD  . MET   D 1 67  ? -25.691 -39.652 -44.853 1.000 68.633  0  177 MET   C SD  1 ? 
ATOM   3334 C  CE  . MET   D 1 67  ? -24.369 -38.713 -45.637 1.000 58.898  0  177 MET   C CE  1 ? 
ATOM   3335 N  N   . THR   D 1 68  ? -21.617 -43.584 -43.025 1.000 32.690  0  178 THR   C N   1 ? 
ATOM   3336 C  CA  . THR   D 1 68  ? -20.277 -43.728 -42.460 1.000 40.082  0  178 THR   C CA  1 ? 
ATOM   3337 C  C   . THR   D 1 68  ? -19.439 -44.642 -43.364 1.000 34.738  0  178 THR   C C   1 ? 
ATOM   3338 O  O   . THR   D 1 68  ? -18.243 -44.420 -43.536 1.000 33.089  0  178 THR   C O   1 ? 
ATOM   3339 C  CB  . THR   D 1 68  ? -20.355 -44.265 -41.027 1.000 40.972  0  178 THR   C CB  1 ? 
ATOM   3340 O  OG1 . THR   D 1 68  ? -20.954 -43.234 -40.242 1.000 36.349  0  178 THR   C OG1 1 ? 
ATOM   3341 C  CG2 . THR   D 1 68  ? -18.989 -44.597 -40.452 1.000 37.607  0  178 THR   C CG2 1 ? 
ATOM   3342 N  N   . ARG   D 1 69  ? -20.096 -45.635 -43.975 1.000 37.637  0  179 ARG   C N   1 ? 
ATOM   3343 C  CA  . ARG   D 1 69  ? -19.416 -46.609 -44.819 1.000 35.103  0  179 ARG   C CA  1 ? 
ATOM   3344 C  C   . ARG   D 1 69  ? -19.177 -46.042 -46.229 1.000 32.391  0  179 ARG   C C   1 ? 
ATOM   3345 O  O   . ARG   D 1 69  ? -18.589 -46.718 -47.067 1.000 35.238  0  179 ARG   C O   1 ? 
ATOM   3346 C  CB  . ARG   D 1 69  ? -20.204 -47.925 -44.862 1.000 32.772  0  179 ARG   C CB  1 ? 
ATOM   3347 C  CG  . ARG   D 1 69  ? -20.172 -48.695 -43.548 1.000 31.423  0  179 ARG   C CG  1 ? 
ATOM   3348 C  CD  . ARG   D 1 69  ? -20.706 -50.109 -43.685 1.000 31.903  0  179 ARG   C CD  1 ? 
ATOM   3349 N  NE  . ARG   D 1 69  ? -22.170 -50.178 -43.787 1.000 35.544  0  179 ARG   C NE  1 ? 
ATOM   3350 C  CZ  . ARG   D 1 69  ? -23.024 -50.101 -42.760 1.000 32.319  0  179 ARG   C CZ  1 ? 
ATOM   3351 N  NH1 . ARG   D 1 69  ? -22.574 -49.982 -41.521 1.000 35.362  0  179 ARG   C NH1 1 ? 
ATOM   3352 N  NH2 . ARG   D 1 69  ? -24.321 -50.198 -42.975 1.000 28.437  0  179 ARG   C NH2 1 ? 
ATOM   3353 N  N   . LYS   D 1 70  ? -19.616 -44.795 -46.476 1.000 32.851  0  180 LYS   C N   1 ? 
ATOM   3354 C  CA  . LYS   D 1 70  ? -19.349 -44.127 -47.747 1.000 30.934  0  180 LYS   C CA  1 ? 
ATOM   3355 C  C   . LYS   D 1 70  ? -18.061 -43.306 -47.640 1.000 36.213  0  180 LYS   C C   1 ? 
ATOM   3356 O  O   . LYS   D 1 70  ? -17.587 -42.766 -48.637 1.000 34.649  0  180 LYS   C O   1 ? 
ATOM   3357 C  CB  . LYS   D 1 70  ? -20.525 -43.246 -48.183 1.000 28.089  0  180 LYS   C CB  1 ? 
ATOM   3358 C  CG  . LYS   D 1 70  ? -21.877 -43.947 -48.236 1.000 29.263  0  180 LYS   C CG  1 ? 
ATOM   3359 C  CD  . LYS   D 1 70  ? -21.877 -45.259 -49.012 1.000 33.290  0  180 LYS   C CD  1 ? 
ATOM   3360 C  CE  . LYS   D 1 70  ? -23.213 -45.926 -49.013 1.000 33.975  0  180 LYS   C CE  1 ? 
ATOM   3361 N  NZ  . LYS   D 1 70  ? -23.143 -47.269 -49.593 1.000 35.429  0  180 LYS   C NZ  1 ? 
ATOM   3362 N  N   . PHE   D 1 71  ? -17.524 -43.193 -46.415 1.000 37.503  0  181 PHE   C N   1 ? 
ATOM   3363 C  CA  . PHE   D 1 71  ? -16.223 -42.580 -46.195 1.000 33.422  0  181 PHE   C CA  1 ? 
ATOM   3364 C  C   . PHE   D 1 71  ? -15.151 -43.661 -46.261 1.000 36.531  0  181 PHE   C C   1 ? 
ATOM   3365 O  O   . PHE   D 1 71  ? -15.378 -44.792 -45.830 1.000 40.013  0  181 PHE   C O   1 ? 
ATOM   3366 C  CB  . PHE   D 1 71  ? -16.184 -41.865 -44.841 1.000 35.659  0  181 PHE   C CB  1 ? 
ATOM   3367 C  CG  . PHE   D 1 71  ? -17.061 -40.628 -44.761 1.000 43.921  0  181 PHE   C CG  1 ? 
ATOM   3368 C  CD1 . PHE   D 1 71  ? -18.402 -40.723 -44.395 1.000 45.424  0  181 PHE   C CD1 1 ? 
ATOM   3369 C  CD2 . PHE   D 1 71  ? -16.550 -39.370 -45.075 1.000 45.764  0  181 PHE   C CD2 1 ? 
ATOM   3370 C  CE1 . PHE   D 1 71  ? -19.204 -39.591 -44.340 1.000 46.890  0  181 PHE   C CE1 1 ? 
ATOM   3371 C  CE2 . PHE   D 1 71  ? -17.359 -38.244 -45.026 1.000 47.196  0  181 PHE   C CE2 1 ? 
ATOM   3372 C  CZ  . PHE   D 1 71  ? -18.684 -38.358 -44.661 1.000 47.717  0  181 PHE   C CZ  1 ? 
ATOM   3373 N  N   . SER   D 1 72  ? -13.993 -43.308 -46.826 1.000 35.509  0  182 SER   C N   1 ? 
ATOM   3374 C  CA  . SER   D 1 72  ? -12.825 -44.168 -46.765 1.000 37.737  0  182 SER   C CA  1 ? 
ATOM   3375 C  C   . SER   D 1 72  ? -12.377 -44.290 -45.309 1.000 33.955  0  182 SER   C C   1 ? 
ATOM   3376 O  O   . SER   D 1 72  ? -12.574 -43.370 -44.518 1.000 30.129  0  182 SER   C O   1 ? 
ATOM   3377 C  CB  . SER   D 1 72  ? -11.706 -43.652 -47.656 1.000 38.814  0  182 SER   C CB  1 ? 
ATOM   3378 O  OG  . SER   D 1 72  ? -11.367 -42.311 -47.337 1.000 46.044  0  182 SER   C OG  1 ? 
ATOM   3379 N  N   . LYS   D 1 73  ? -11.789 -45.441 -44.968 1.000 37.073  0  183 LYS   C N   1 ? 
ATOM   3380 C  CA  . LYS   D 1 73  ? -11.385 -45.736 -43.598 1.000 47.334  0  183 LYS   C CA  1 ? 
ATOM   3381 C  C   . LYS   D 1 73  ? -10.360 -44.702 -43.105 1.000 36.915  0  183 LYS   C C   1 ? 
ATOM   3382 O  O   . LYS   D 1 73  ? -10.253 -44.463 -41.907 1.000 40.473  0  183 LYS   C O   1 ? 
ATOM   3383 C  CB  . LYS   D 1 73  ? -10.825 -47.164 -43.519 1.000 53.749  0  183 LYS   C CB  1 ? 
ATOM   3384 C  CG  . LYS   D 1 73  ? -10.464 -47.650 -42.111 1.000 64.867  0  183 LYS   C CG  1 ? 
ATOM   3385 C  CD  . LYS   D 1 73  ? -10.037 -49.114 -42.038 1.000 75.572  0  183 LYS   C CD  1 ? 
ATOM   3386 C  CE  . LYS   D 1 73  ? -11.161 -50.068 -42.318 1.000 88.113  0  183 LYS   C CE  1 ? 
ATOM   3387 N  NZ  . LYS   D 1 73  ? -10.719 -51.462 -42.252 1.000 100.227 0  183 LYS   C NZ  1 ? 
ATOM   3388 N  N   . SER   D 1 74  ? -9.637  -44.077 -44.045 1.000 32.745  0  184 SER   C N   1 ? 
ATOM   3389 C  CA  . SER   D 1 74  ? -8.592  -43.115 -43.717 1.000 40.917  0  184 SER   C CA  1 ? 
ATOM   3390 C  C   . SER   D 1 74  ? -9.184  -41.767 -43.267 1.000 44.920  0  184 SER   C C   1 ? 
ATOM   3391 O  O   . SER   D 1 74  ? -8.465  -40.937 -42.714 1.000 51.816  0  184 SER   C O   1 ? 
ATOM   3392 C  CB  . SER   D 1 74  ? -7.655  -42.931 -44.888 1.000 44.913  0  184 SER   C CB  1 ? 
ATOM   3393 O  OG  . SER   D 1 74  ? -8.370  -42.579 -46.066 1.000 52.442  0  184 SER   C OG  1 ? 
ATOM   3394 N  N   . GLN   D 1 75  ? -10.491 -41.557 -43.507 1.000 41.089  0  185 GLN   C N   1 ? 
ATOM   3395 C  CA  . GLN   D 1 75  ? -11.141 -40.287 -43.186 1.000 41.458  0  185 GLN   C CA  1 ? 
ATOM   3396 C  C   . GLN   D 1 75  ? -11.778 -40.320 -41.791 1.000 36.241  0  185 GLN   C C   1 ? 
ATOM   3397 O  O   . GLN   D 1 75  ? -12.206 -39.280 -41.290 1.000 36.983  0  185 GLN   C O   1 ? 
ATOM   3398 C  CB  . GLN   D 1 75  ? -12.216 -39.936 -44.219 1.000 46.123  0  185 GLN   C CB  1 ? 
ATOM   3399 C  CG  . GLN   D 1 75  ? -11.693 -39.195 -45.444 1.000 51.058  0  185 GLN   C CG  1 ? 
ATOM   3400 C  CD  . GLN   D 1 75  ? -11.109 -37.837 -45.110 1.000 46.368  0  185 GLN   C CD  1 ? 
ATOM   3401 O  OE1 . GLN   D 1 75  ? -9.986  -37.725 -44.613 1.000 56.194  0  185 GLN   C OE1 1 ? 
ATOM   3402 N  NE2 . GLN   D 1 75  ? -11.852 -36.785 -45.426 1.000 49.223  0  185 GLN   C NE2 1 ? 
ATOM   3403 N  N   . LEU   D 1 76  ? -11.820 -41.501 -41.162 1.000 32.530  0  186 LEU   C N   1 ? 
ATOM   3404 C  CA  . LEU   D 1 76  ? -12.573 -41.679 -39.925 1.000 37.840  0  186 LEU   C CA  1 ? 
ATOM   3405 C  C   . LEU   D 1 76  ? -12.006 -40.793 -38.806 1.000 38.596  0  186 LEU   C C   1 ? 
ATOM   3406 O  O   . LEU   D 1 76  ? -12.758 -40.329 -37.952 1.000 48.015  0  186 LEU   C O   1 ? 
ATOM   3407 C  CB  . LEU   D 1 76  ? -12.593 -43.151 -39.520 1.000 39.027  0  186 LEU   C CB  1 ? 
ATOM   3408 C  CG  . LEU   D 1 76  ? -13.385 -44.093 -40.436 1.000 44.003  0  186 LEU   C CG  1 ? 
ATOM   3409 C  CD1 . LEU   D 1 76  ? -13.443 -45.487 -39.829 1.000 46.804  0  186 LEU   C CD1 1 ? 
ATOM   3410 C  CD2 . LEU   D 1 76  ? -14.793 -43.576 -40.718 1.000 41.056  0  186 LEU   C CD2 1 ? 
ATOM   3411 N  N   . SER   D 1 77  ? -10.682 -40.574 -38.813 1.000 37.904  0  187 SER   C N   1 ? 
ATOM   3412 C  CA  . SER   D 1 77  ? -10.029 -39.774 -37.781 1.000 39.160  0  187 SER   C CA  1 ? 
ATOM   3413 C  C   . SER   D 1 77  ? -10.442 -38.303 -37.901 1.000 35.144  0  187 SER   C C   1 ? 
ATOM   3414 O  O   . SER   D 1 77  ? -10.642 -37.631 -36.891 1.000 33.303  0  187 SER   C O   1 ? 
ATOM   3415 C  CB  . SER   D 1 77  ? -8.524  -39.932 -37.831 1.000 41.659  0  187 SER   C CB  1 ? 
ATOM   3416 O  OG  . SER   D 1 77  ? -8.021  -39.635 -39.124 1.000 58.715  0  187 SER   C OG  1 ? 
ATOM   3417 N  N   . LEU   D 1 78  ? -10.583 -37.818 -39.144 1.000 33.044  0  188 LEU   C N   1 ? 
ATOM   3418 C  CA  . LEU   D 1 78  ? -10.999 -36.439 -39.390 1.000 37.810  0  188 LEU   C CA  1 ? 
ATOM   3419 C  C   . LEU   D 1 78  ? -12.489 -36.297 -39.065 1.000 38.237  0  188 LEU   C C   1 ? 
ATOM   3420 O  O   . LEU   D 1 78  ? -12.925 -35.263 -38.560 1.000 37.195  0  188 LEU   C O   1 ? 
ATOM   3421 C  CB  . LEU   D 1 78  ? -10.695 -36.045 -40.838 1.000 41.644  0  188 LEU   C CB  1 ? 
ATOM   3422 C  CG  . LEU   D 1 78  ? -11.018 -34.595 -41.228 1.000 44.535  0  188 LEU   C CG  1 ? 
ATOM   3423 C  CD1 . LEU   D 1 78  ? -10.125 -33.599 -40.496 1.000 44.251  0  188 LEU   C CD1 1 ? 
ATOM   3424 C  CD2 . LEU   D 1 78  ? -10.902 -34.406 -42.730 1.000 43.226  0  188 LEU   C CD2 1 ? 
ATOM   3425 N  N   . LEU   D 1 79  ? -13.259 -37.346 -39.373 1.000 38.894  0  189 LEU   C N   1 ? 
ATOM   3426 C  CA  . LEU   D 1 79  ? -14.669 -37.395 -39.028 1.000 39.899  0  189 LEU   C CA  1 ? 
ATOM   3427 C  C   . LEU   D 1 79  ? -14.819 -37.238 -37.514 1.000 43.008  0  189 LEU   C C   1 ? 
ATOM   3428 O  O   . LEU   D 1 79  ? -15.645 -36.455 -37.043 1.000 41.286  0  189 LEU   C O   1 ? 
ATOM   3429 C  CB  . LEU   D 1 79  ? -15.267 -38.710 -39.528 1.000 41.136  0  189 LEU   C CB  1 ? 
ATOM   3430 C  CG  . LEU   D 1 79  ? -16.731 -38.974 -39.165 1.000 48.107  0  189 LEU   C CG  1 ? 
ATOM   3431 C  CD1 . LEU   D 1 79  ? -17.665 -37.956 -39.807 1.000 51.048  0  189 LEU   C CD1 1 ? 
ATOM   3432 C  CD2 . LEU   D 1 79  ? -17.120 -40.383 -39.559 1.000 52.316  0  189 LEU   C CD2 1 ? 
ATOM   3433 N  N   . CYS   D 1 80  ? -13.992 -37.977 -36.765 1.000 39.284  0  190 CYS   C N   1 ? 
ATOM   3434 C  CA  . CYS   D 1 80  ? -13.984 -37.898 -35.312 1.000 44.940  0  190 CYS   C CA  1 ? 
ATOM   3435 C  C   . CYS   D 1 80  ? -13.604 -36.483 -34.865 1.000 37.345  0  190 CYS   C C   1 ? 
ATOM   3436 O  O   . CYS   D 1 80  ? -14.285 -35.890 -34.039 1.000 42.198  0  190 CYS   C O   1 ? 
ATOM   3437 C  CB  . CYS   D 1 80  ? -13.030 -38.925 -34.712 1.000 45.638  0  190 CYS   C CB  1 ? 
ATOM   3438 S  SG  . CYS   D 1 80  ? -12.967 -38.882 -32.901 1.000 45.851  0  190 CYS   C SG  1 ? 
ATOM   3439 N  N   . GLU   D 1 81  ? -12.522 -35.951 -35.445 1.000 33.855  0  191 GLU   C N   1 ? 
ATOM   3440 C  CA  . GLU   D 1 81  ? -12.001 -34.641 -35.075 1.000 37.134  0  191 GLU   C CA  1 ? 
ATOM   3441 C  C   . GLU   D 1 81  ? -13.078 -33.574 -35.278 1.000 37.301  0  191 GLU   C C   1 ? 
ATOM   3442 O  O   . GLU   D 1 81  ? -13.309 -32.749 -34.398 1.000 41.629  0  191 GLU   C O   1 ? 
ATOM   3443 C  CB  . GLU   D 1 81  ? -10.755 -34.328 -35.910 1.000 38.988  0  191 GLU   C CB  1 ? 
ATOM   3444 C  CG  . GLU   D 1 81  ? -10.058 -33.025 -35.520 1.000 48.516  0  191 GLU   C CG  1 ? 
ATOM   3445 C  CD  . GLU   D 1 81  ? -9.351  -33.043 -34.173 1.000 60.582  0  191 GLU   C CD  1 ? 
ATOM   3446 O  OE1 . GLU   D 1 81  ? -9.313  -34.113 -33.521 1.000 64.568  0  191 GLU   C OE1 1 ? 
ATOM   3447 O  OE2 . GLU   D 1 81  ? -8.832  -31.975 -33.775 1.000 65.422  0  191 GLU   C OE2 1 ? 
ATOM   3448 N  N   . THR   D 1 82  ? -13.734 -33.608 -36.445 1.000 34.757  0  192 THR   C N   1 ? 
ATOM   3449 C  CA  . THR   D 1 82  ? -14.735 -32.612 -36.806 1.000 32.377  0  192 THR   C CA  1 ? 
ATOM   3450 C  C   . THR   D 1 82  ? -15.966 -32.757 -35.896 1.000 33.496  0  192 THR   C C   1 ? 
ATOM   3451 O  O   . THR   D 1 82  ? -16.656 -31.777 -35.624 1.000 35.432  0  192 THR   C O   1 ? 
ATOM   3452 C  CB  . THR   D 1 82  ? -15.098 -32.768 -38.287 1.000 32.813  0  192 THR   C CB  1 ? 
ATOM   3453 O  OG1 . THR   D 1 82  ? -13.864 -32.879 -38.997 1.000 33.478  0  192 THR   C OG1 1 ? 
ATOM   3454 C  CG2 . THR   D 1 82  ? -15.871 -31.581 -38.828 1.000 29.733  0  192 THR   C CG2 1 ? 
ATOM   3455 N  N   . HIS   D 1 83  ? -16.240 -33.994 -35.455 1.000 32.187  0  193 HIS   C N   1 ? 
ATOM   3456 C  CA  . HIS   D 1 83  ? -17.360 -34.279 -34.569 1.000 34.385  0  193 HIS   C CA  1 ? 
ATOM   3457 C  C   . HIS   D 1 83  ? -17.093 -33.661 -33.190 1.000 35.770  0  193 HIS   C C   1 ? 
ATOM   3458 O  O   . HIS   D 1 83  ? -17.957 -32.985 -32.635 1.000 32.512  0  193 HIS   C O   1 ? 
ATOM   3459 C  CB  . HIS   D 1 83  ? -17.619 -35.794 -34.517 1.000 32.114  0  193 HIS   C CB  1 ? 
ATOM   3460 C  CG  . HIS   D 1 83  ? -18.809 -36.208 -33.714 1.000 29.662  0  193 HIS   C CG  1 ? 
ATOM   3461 N  ND1 . HIS   D 1 83  ? -19.751 -37.077 -34.217 1.000 30.040  0  193 HIS   C ND1 1 ? 
ATOM   3462 C  CD2 . HIS   D 1 83  ? -19.243 -35.867 -32.487 1.000 32.437  0  193 HIS   C CD2 1 ? 
ATOM   3463 C  CE1 . HIS   D 1 83  ? -20.700 -37.269 -33.312 1.000 33.401  0  193 HIS   C CE1 1 ? 
ATOM   3464 N  NE2 . HIS   D 1 83  ? -20.406 -36.555 -32.251 1.000 34.168  0  193 HIS   C NE2 1 ? 
ATOM   3465 N  N   . LEU   D 1 84  ? -15.881 -33.885 -32.661 1.000 31.124  0  194 LEU   C N   1 ? 
ATOM   3466 C  CA  . LEU   D 1 84  ? -15.497 -33.377 -31.344 1.000 38.291  0  194 LEU   C CA  1 ? 
ATOM   3467 C  C   . LEU   D 1 84  ? -15.650 -31.856 -31.305 1.000 41.016  0  194 LEU   C C   1 ? 
ATOM   3468 O  O   . LEU   D 1 84  ? -16.187 -31.307 -30.344 1.000 41.786  0  194 LEU   C O   1 ? 
ATOM   3469 C  CB  . LEU   D 1 84  ? -14.059 -33.780 -31.012 1.000 39.755  0  194 LEU   C CB  1 ? 
ATOM   3470 C  CG  . LEU   D 1 84  ? -13.771 -35.281 -30.902 1.000 41.884  0  194 LEU   C CG  1 ? 
ATOM   3471 C  CD1 . LEU   D 1 84  ? -12.277 -35.496 -30.804 1.000 45.626  0  194 LEU   C CD1 1 ? 
ATOM   3472 C  CD2 . LEU   D 1 84  ? -14.485 -35.926 -29.719 1.000 44.159  0  194 LEU   C CD2 1 ? 
ATOM   3473 N  N   . ARG   D 1 85  ? -15.122 -31.183 -32.336 1.000 38.719  0  195 ARG   C N   1 ? 
ATOM   3474 C  CA  . ARG   D 1 85  ? -15.065 -29.731 -32.356 1.000 36.942  0  195 ARG   C CA  1 ? 
ATOM   3475 C  C   . ARG   D 1 85  ? -16.481 -29.149 -32.432 1.000 37.985  0  195 ARG   C C   1 ? 
ATOM   3476 O  O   . ARG   D 1 85  ? -16.784 -28.182 -31.743 1.000 43.089  0  195 ARG   C O   1 ? 
ATOM   3477 C  CB  . ARG   D 1 85  ? -14.159 -29.239 -33.492 1.000 36.235  0  195 ARG   C CB  1 ? 
ATOM   3478 C  CG  . ARG   D 1 85  ? -12.674 -29.555 -33.334 1.000 36.843  0  195 ARG   C CG  1 ? 
ATOM   3479 C  CD  . ARG   D 1 85  ? -12.036 -28.913 -32.087 1.000 38.745  0  195 ARG   C CD  1 ? 
ATOM   3480 N  NE  . ARG   D 1 85  ? -12.149 -29.747 -30.880 1.000 39.206  0  195 ARG   C NE  1 ? 
ATOM   3481 C  CZ  . ARG   D 1 85  ? -11.461 -30.879 -30.648 1.000 42.790  0  195 ARG   C CZ  1 ? 
ATOM   3482 N  NH1 . ARG   D 1 85  ? -10.514 -31.275 -31.487 1.000 41.628  0  195 ARG   C NH1 1 ? 
ATOM   3483 N  NH2 . ARG   D 1 85  ? -11.686 -31.574 -29.540 1.000 43.161  0  195 ARG   C NH2 1 ? 
ATOM   3484 N  N   . ARG   D 1 86  ? -17.360 -29.779 -33.230 1.000 33.303  0  196 ARG   C N   1 ? 
ATOM   3485 C  CA  . ARG   D 1 86  ? -18.724 -29.289 -33.395 1.000 33.100  0  196 ARG   C CA  1 ? 
ATOM   3486 C  C   . ARG   D 1 86  ? -19.469 -29.343 -32.055 1.000 32.043  0  196 ARG   C C   1 ? 
ATOM   3487 O  O   . ARG   D 1 86  ? -20.200 -28.419 -31.716 1.000 36.251  0  196 ARG   C O   1 ? 
ATOM   3488 C  CB  . ARG   D 1 86  ? -19.500 -30.083 -34.453 1.000 35.797  0  196 ARG   C CB  1 ? 
ATOM   3489 C  CG  . ARG   D 1 86  ? -20.793 -29.396 -34.869 1.000 40.868  0  196 ARG   C CG  1 ? 
ATOM   3490 C  CD  . ARG   D 1 86  ? -21.749 -30.296 -35.613 1.000 43.403  0  196 ARG   C CD  1 ? 
ATOM   3491 N  NE  . ARG   D 1 86  ? -22.993 -29.576 -35.914 1.000 45.669  0  196 ARG   C NE  1 ? 
ATOM   3492 C  CZ  . ARG   D 1 86  ? -24.144 -29.681 -35.240 1.000 41.773  0  196 ARG   C CZ  1 ? 
ATOM   3493 N  NH1 . ARG   D 1 86  ? -24.230 -30.448 -34.162 1.000 37.937  0  196 ARG   C NH1 1 ? 
ATOM   3494 N  NH2 . ARG   D 1 86  ? -25.193 -28.968 -35.619 1.000 47.493  0  196 ARG   C NH2 1 ? 
ATOM   3495 N  N   . GLU   D 1 87  ? -19.263 -30.432 -31.298 1.000 33.543  0  197 GLU   C N   1 ? 
ATOM   3496 C  CA  . GLU   D 1 87  ? -19.996 -30.666 -30.059 1.000 34.783  0  197 GLU   C CA  1 ? 
ATOM   3497 C  C   . GLU   D 1 87  ? -19.262 -30.043 -28.871 1.000 34.613  0  197 GLU   C C   1 ? 
ATOM   3498 O  O   . GLU   D 1 87  ? -19.822 -29.958 -27.778 1.000 34.421  0  197 GLU   C O   1 ? 
ATOM   3499 C  CB  . GLU   D 1 87  ? -20.221 -32.165 -29.863 1.000 35.291  0  197 GLU   C CB  1 ? 
ATOM   3500 C  CG  . GLU   D 1 87  ? -20.998 -32.794 -31.014 1.000 46.005  0  197 GLU   C CG  1 ? 
ATOM   3501 C  CD  . GLU   D 1 87  ? -22.261 -32.029 -31.378 1.000 48.717  0  197 GLU   C CD  1 ? 
ATOM   3502 O  OE1 . GLU   D 1 87  ? -22.287 -31.422 -32.472 1.000 51.929  0  197 GLU   C OE1 1 ? 
ATOM   3503 O  OE2 . GLU   D 1 87  ? -23.203 -32.019 -30.561 1.000 57.793  0  197 GLU   C OE2 1 ? 
ATOM   3504 N  N   . GLY   D 1 88  ? -18.008 -29.623 -29.092 1.000 32.343  0  198 GLY   C N   1 ? 
ATOM   3505 C  CA  . GLY   D 1 88  ? -17.235 -28.924 -28.072 1.000 34.031  0  198 GLY   C CA  1 ? 
ATOM   3506 C  C   . GLY   D 1 88  ? -16.643 -29.889 -27.047 1.000 32.401  0  198 GLY   C C   1 ? 
ATOM   3507 O  O   . GLY   D 1 88  ? -16.397 -29.507 -25.907 1.000 35.243  0  198 GLY   C O   1 ? 
ATOM   3508 N  N   . LEU   D 1 89  ? -16.394 -31.134 -27.482 1.000 36.948  0  199 LEU   C N   1 ? 
ATOM   3509 C  CA  . LEU   D 1 89  ? -15.828 -32.169 -26.622 1.000 36.518  0  199 LEU   C CA  1 ? 
ATOM   3510 C  C   . LEU   D 1 89  ? -14.305 -32.025 -26.587 1.000 36.342  0  199 LEU   C C   1 ? 
ATOM   3511 O  O   . LEU   D 1 89  ? -13.690 -31.623 -27.580 1.000 36.499  0  199 LEU   C O   1 ? 
ATOM   3512 C  CB  . LEU   D 1 89  ? -16.245 -33.540 -27.156 1.000 39.150  0  199 LEU   C CB  1 ? 
ATOM   3513 C  CG  . LEU   D 1 89  ? -17.748 -33.849 -27.130 1.000 40.064  0  199 LEU   C CG  1 ? 
ATOM   3514 C  CD1 . LEU   D 1 89  ? -18.094 -34.931 -28.135 1.000 42.856  0  199 LEU   C CD1 1 ? 
ATOM   3515 C  CD2 . LEU   D 1 89  ? -18.196 -34.260 -25.737 1.000 40.757  0  199 LEU   C CD2 1 ? 
ATOM   3516 N  N   . GLY   D 1 90  ? -13.708 -32.381 -25.439 1.000 35.734  0  200 GLY   C N   1 ? 
ATOM   3517 C  CA  . GLY   D 1 90  ? -12.261 -32.389 -25.282 1.000 39.264  0  200 GLY   C CA  1 ? 
ATOM   3518 C  C   . GLY   D 1 90  ? -11.633 -33.544 -26.059 1.000 51.669  0  200 GLY   C C   1 ? 
ATOM   3519 O  O   . GLY   D 1 90  ? -12.338 -34.449 -26.511 1.000 50.920  0  200 GLY   C O   1 ? 
ATOM   3520 N  N   . GLN   D 1 91  ? -10.295 -33.540 -26.143 1.000 54.748  0  201 GLN   C N   1 ? 
ATOM   3521 C  CA  . GLN   D 1 91  ? -9.572  -34.501 -26.965 1.000 50.694  0  201 GLN   C CA  1 ? 
ATOM   3522 C  C   . GLN   D 1 91  ? -9.538  -35.869 -26.268 1.000 50.224  0  201 GLN   C C   1 ? 
ATOM   3523 O  O   . GLN   D 1 91  ? -9.174  -36.868 -26.883 1.000 58.675  0  201 GLN   C O   1 ? 
ATOM   3524 C  CB  . GLN   D 1 91  ? -8.162  -33.992 -27.279 1.000 48.074  0  201 GLN   C CB  1 ? 
ATOM   3525 C  CG  . GLN   D 1 91  ? -7.565  -34.575 -28.560 1.000 49.831  0  201 GLN   C CG  1 ? 
ATOM   3526 C  CD  . GLN   D 1 91  ? -8.296  -34.133 -29.816 1.000 57.573  0  201 GLN   C CD  1 ? 
ATOM   3527 O  OE1 . GLN   D 1 91  ? -9.063  -33.161 -29.812 1.000 58.203  0  201 GLN   C OE1 1 ? 
ATOM   3528 N  NE2 . GLN   D 1 91  ? -8.026  -34.817 -30.920 1.000 54.680  0  201 GLN   C NE2 1 ? 
ATOM   3529 N  N   . ASP   D 1 92  ? -9.957  -35.905 -24.992 1.000 51.919  0  202 ASP   C N   1 ? 
ATOM   3530 C  CA  . ASP   D 1 92  ? -10.032 -37.149 -24.236 1.000 55.556  0  202 ASP   C CA  1 ? 
ATOM   3531 C  C   . ASP   D 1 92  ? -11.205 -38.005 -24.738 1.000 55.176  0  202 ASP   C C   1 ? 
ATOM   3532 O  O   . ASP   D 1 92  ? -11.288 -39.186 -24.412 1.000 58.680  0  202 ASP   C O   1 ? 
ATOM   3533 C  CB  . ASP   D 1 92  ? -10.169 -36.884 -22.744 1.000 59.604  0  202 ASP   C CB  1 ? 
ATOM   3534 C  CG  . ASP   D 1 92  ? -11.506 -36.302 -22.306 1.000 71.889  0  202 ASP   C CG  1 ? 
ATOM   3535 O  OD1 . ASP   D 1 92  ? -11.827 -35.177 -22.742 1.000 90.171  0  202 ASP   C OD1 1 ? 
ATOM   3536 O  OD2 . ASP   D 1 92  ? -12.232 -36.997 -21.569 1.000 79.813  0  202 ASP   C OD2 1 ? 
ATOM   3537 N  N   . GLN   D 1 93  ? -12.117 -37.388 -25.513 1.000 55.367  0  203 GLN   C N   1 ? 
ATOM   3538 C  CA  . GLN   D 1 93  ? -13.306 -38.071 -26.014 1.000 49.480  0  203 GLN   C CA  1 ? 
ATOM   3539 C  C   . GLN   D 1 93  ? -13.070 -38.602 -27.435 1.000 47.899  0  203 GLN   C C   1 ? 
ATOM   3540 O  O   . GLN   D 1 93  ? -13.984 -39.152 -28.045 1.000 53.852  0  203 GLN   C O   1 ? 
ATOM   3541 C  CB  . GLN   D 1 93  ? -14.498 -37.113 -26.012 1.000 56.595  0  203 GLN   C CB  1 ? 
ATOM   3542 C  CG  . GLN   D 1 93  ? -14.860 -36.566 -24.635 1.000 60.149  0  203 GLN   C CG  1 ? 
ATOM   3543 C  CD  . GLN   D 1 93  ? -15.310 -37.640 -23.669 1.000 68.947  0  203 GLN   C CD  1 ? 
ATOM   3544 O  OE1 . GLN   D 1 93  ? -16.181 -38.461 -23.979 1.000 68.222  0  203 GLN   C OE1 1 ? 
ATOM   3545 N  NE2 . GLN   D 1 93  ? -14.696 -37.665 -22.494 1.000 69.321  0  203 GLN   C NE2 1 ? 
ATOM   3546 N  N   . ALA   D 1 94  ? -11.839 -38.444 -27.949 1.000 43.980  0  204 ALA   C N   1 ? 
ATOM   3547 C  CA  . ALA   D 1 94  ? -11.504 -38.885 -29.299 1.000 48.219  0  204 ALA   C CA  1 ? 
ATOM   3548 C  C   . ALA   D 1 94  ? -11.537 -40.414 -29.381 1.000 53.090  0  204 ALA   C C   1 ? 
ATOM   3549 O  O   . ALA   D 1 94  ? -11.967 -40.971 -30.387 1.000 50.458  0  204 ALA   C O   1 ? 
ATOM   3550 C  CB  . ALA   D 1 94  ? -10.153 -38.339 -29.705 1.000 45.446  0  204 ALA   C CB  1 ? 
ATOM   3551 N  N   . GLU   D 1 95  ? -11.076 -41.075 -28.309 1.000 54.219  0  205 GLU   C N   1 ? 
ATOM   3552 C  CA  . GLU   D 1 95  ? -11.049 -42.532 -28.240 1.000 52.550  0  205 GLU   C CA  1 ? 
ATOM   3553 C  C   . GLU   D 1 95  ? -12.460 -43.096 -28.469 1.000 45.640  0  205 GLU   C C   1 ? 
ATOM   3554 O  O   . GLU   D 1 95  ? -12.687 -43.799 -29.448 1.000 42.781  0  205 GLU   C O   1 ? 
ATOM   3555 C  CB  . GLU   D 1 95  ? -10.440 -42.984 -26.908 1.000 59.513  0  205 GLU   C CB  1 ? 
ATOM   3556 C  CG  . GLU   D 1 95  ? -10.659 -44.465 -26.598 1.000 69.491  0  205 GLU   C CG  1 ? 
ATOM   3557 C  CD  . GLU   D 1 95  ? -10.460 -44.823 -25.134 1.000 73.596  0  205 GLU   C CD  1 ? 
ATOM   3558 O  OE1 . GLU   D 1 95  ? -11.438 -45.281 -24.503 1.000 65.312  0  205 GLU   C OE1 1 ? 
ATOM   3559 O  OE2 . GLU   D 1 95  ? -9.338  -44.629 -24.620 1.000 79.609  0  205 GLU   C OE2 1 ? 
ATOM   3560 N  N   . PRO   D 1 96  ? -13.443 -42.836 -27.565 1.000 46.595  0  206 PRO   C N   1 ? 
ATOM   3561 C  CA  . PRO   D 1 96  ? -14.782 -43.423 -27.698 1.000 44.661  0  206 PRO   C CA  1 ? 
ATOM   3562 C  C   . PRO   D 1 96  ? -15.527 -43.049 -28.986 1.000 46.298  0  206 PRO   C C   1 ? 
ATOM   3563 O  O   . PRO   D 1 96  ? -16.208 -43.888 -29.570 1.000 50.476  0  206 PRO   C O   1 ? 
ATOM   3564 C  CB  . PRO   D 1 96  ? -15.522 -42.914 -26.420 1.000 42.576  0  206 PRO   C CB  1 ? 
ATOM   3565 C  CG  . PRO   D 1 96  ? -14.718 -41.701 -25.978 1.000 43.201  0  206 PRO   C CG  1 ? 
ATOM   3566 C  CD  . PRO   D 1 96  ? -13.295 -42.041 -26.337 1.000 45.673  0  206 PRO   C CD  1 ? 
ATOM   3567 N  N   . VAL   D 1 97  ? -15.394 -41.784 -29.412 1.000 46.256  0  207 VAL   C N   1 ? 
ATOM   3568 C  CA  . VAL   D 1 97  ? -16.103 -41.286 -30.585 1.000 41.649  0  207 VAL   C CA  1 ? 
ATOM   3569 C  C   . VAL   D 1 97  ? -15.549 -41.966 -31.842 1.000 39.278  0  207 VAL   C C   1 ? 
ATOM   3570 O  O   . VAL   D 1 97  ? -16.313 -42.357 -32.723 1.000 40.346  0  207 VAL   C O   1 ? 
ATOM   3571 C  CB  . VAL   D 1 97  ? -16.025 -39.748 -30.691 1.000 41.253  0  207 VAL   C CB  1 ? 
ATOM   3572 C  CG1 . VAL   D 1 97  ? -16.553 -39.237 -32.031 1.000 38.987  0  207 VAL   C CG1 1 ? 
ATOM   3573 C  CG2 . VAL   D 1 97  ? -16.756 -39.068 -29.539 1.000 40.066  0  207 VAL   C CG2 1 ? 
ATOM   3574 N  N   . LEU   D 1 98  ? -14.219 -42.090 -31.921 1.000 36.316  0  208 LEU   C N   1 ? 
ATOM   3575 C  CA  . LEU   D 1 98  ? -13.576 -42.744 -33.054 1.000 38.048  0  208 LEU   C CA  1 ? 
ATOM   3576 C  C   . LEU   D 1 98  ? -14.009 -44.208 -33.112 1.000 41.104  0  208 LEU   C C   1 ? 
ATOM   3577 O  O   . LEU   D 1 98  ? -14.231 -44.748 -34.196 1.000 41.351  0  208 LEU   C O   1 ? 
ATOM   3578 C  CB  . LEU   D 1 98  ? -12.056 -42.622 -32.951 1.000 41.556  0  208 LEU   C CB  1 ? 
ATOM   3579 C  CG  . LEU   D 1 98  ? -11.249 -43.241 -34.098 1.000 42.638  0  208 LEU   C CG  1 ? 
ATOM   3580 C  CD1 . LEU   D 1 98  ? -11.515 -42.523 -35.412 1.000 43.712  0  208 LEU   C CD1 1 ? 
ATOM   3581 C  CD2 . LEU   D 1 98  ? -9.764  -43.235 -33.778 1.000 45.042  0  208 LEU   C CD2 1 ? 
ATOM   3582 N  N   . GLU   D 1 99  ? -14.120 -44.842 -31.934 1.000 43.205  0  209 GLU   C N   1 ? 
ATOM   3583 C  CA  . GLU   D 1 99  ? -14.465 -46.253 -31.851 1.000 48.341  0  209 GLU   C CA  1 ? 
ATOM   3584 C  C   . GLU   D 1 99  ? -15.844 -46.479 -32.475 1.000 41.136  0  209 GLU   C C   1 ? 
ATOM   3585 O  O   . GLU   D 1 99  ? -16.033 -47.432 -33.220 1.000 40.605  0  209 GLU   C O   1 ? 
ATOM   3586 C  CB  . GLU   D 1 99  ? -14.434 -46.766 -30.409 1.000 54.896  0  209 GLU   C CB  1 ? 
ATOM   3587 C  CG  . GLU   D 1 99  ? -14.324 -48.288 -30.327 1.000 69.769  0  209 GLU   C CG  1 ? 
ATOM   3588 C  CD  . GLU   D 1 99  ? -14.430 -48.880 -28.935 1.000 83.688  0  209 GLU   C CD  1 ? 
ATOM   3589 O  OE1 . GLU   D 1 99  ? -13.633 -48.488 -28.056 1.000 94.701  0  209 GLU   C OE1 1 ? 
ATOM   3590 O  OE2 . GLU   D 1 99  ? -15.277 -49.783 -28.748 1.000 91.053  0  209 GLU   C OE2 1 ? 
ATOM   3591 N  N   . VAL   D 1 100 ? -16.791 -45.575 -32.175 1.000 39.122  0  210 VAL   C N   1 ? 
ATOM   3592 C  CA  . VAL   D 1 100 ? -18.147 -45.666 -32.701 1.000 35.328  0  210 VAL   C CA  1 ? 
ATOM   3593 C  C   . VAL   D 1 100 ? -18.096 -45.679 -34.232 1.000 35.965  0  210 VAL   C C   1 ? 
ATOM   3594 O  O   . VAL   D 1 100 ? -18.686 -46.550 -34.863 1.000 34.631  0  210 VAL   C O   1 ? 
ATOM   3595 C  CB  . VAL   D 1 100 ? -19.034 -44.515 -32.178 1.000 40.278  0  210 VAL   C CB  1 ? 
ATOM   3596 C  CG1 . VAL   D 1 100 ? -20.348 -44.404 -32.949 1.000 40.095  0  210 VAL   C CG1 1 ? 
ATOM   3597 C  CG2 . VAL   D 1 100 ? -19.302 -44.644 -30.684 1.000 39.659  0  210 VAL   C CG2 1 ? 
ATOM   3598 N  N   . TYR   D 1 101 ? -17.361 -44.719 -34.813 1.000 41.696  0  211 TYR   C N   1 ? 
ATOM   3599 C  CA  . TYR   D 1 101 ? -17.289 -44.567 -36.263 1.000 38.850  0  211 TYR   C CA  1 ? 
ATOM   3600 C  C   . TYR   D 1 101 ? -16.573 -45.768 -36.880 1.000 36.787  0  211 TYR   C C   1 ? 
ATOM   3601 O  O   . TYR   D 1 101 ? -16.993 -46.269 -37.919 1.000 35.600  0  211 TYR   C O   1 ? 
ATOM   3602 C  CB  . TYR   D 1 101 ? -16.619 -43.236 -36.627 1.000 37.034  0  211 TYR   C CB  1 ? 
ATOM   3603 C  CG  . TYR   D 1 101 ? -17.532 -42.020 -36.523 1.000 36.883  0  211 TYR   C CG  1 ? 
ATOM   3604 C  CD1 . TYR   D 1 101 ? -18.820 -42.040 -37.052 1.000 42.470  0  211 TYR   C CD1 1 ? 
ATOM   3605 C  CD2 . TYR   D 1 101 ? -17.128 -40.871 -35.854 1.000 37.475  0  211 TYR   C CD2 1 ? 
ATOM   3606 C  CE1 . TYR   D 1 101 ? -19.659 -40.943 -36.956 1.000 38.222  0  211 TYR   C CE1 1 ? 
ATOM   3607 C  CE2 . TYR   D 1 101 ? -17.966 -39.772 -35.734 1.000 37.070  0  211 TYR   C CE2 1 ? 
ATOM   3608 C  CZ  . TYR   D 1 101 ? -19.234 -39.808 -36.292 1.000 39.051  0  211 TYR   C CZ  1 ? 
ATOM   3609 O  OH  . TYR   D 1 101 ? -20.066 -38.731 -36.193 1.000 41.423  0  211 TYR   C OH  1 ? 
ATOM   3610 N  N   . GLN   D 1 102 ? -15.484 -46.214 -36.241 1.000 38.478  0  212 GLN   C N   1 ? 
ATOM   3611 C  CA  . GLN   D 1 102 ? -14.733 -47.367 -36.724 1.000 38.803  0  212 GLN   C CA  1 ? 
ATOM   3612 C  C   . GLN   D 1 102 ? -15.641 -48.598 -36.762 1.000 35.662  0  212 GLN   C C   1 ? 
ATOM   3613 O  O   . GLN   D 1 102 ? -15.668 -49.323 -37.758 1.000 32.220  0  212 GLN   C O   1 ? 
ATOM   3614 C  CB  . GLN   D 1 102 ? -13.501 -47.633 -35.858 1.000 38.588  0  212 GLN   C CB  1 ? 
ATOM   3615 C  CG  . GLN   D 1 102 ? -12.331 -46.692 -36.132 1.000 45.125  0  212 GLN   C CG  1 ? 
ATOM   3616 C  CD  . GLN   D 1 102 ? -11.143 -46.932 -35.219 1.000 50.302  0  212 GLN   C CD  1 ? 
ATOM   3617 O  OE1 . GLN   D 1 102 ? -11.229 -47.662 -34.221 1.000 46.434  0  212 GLN   C OE1 1 ? 
ATOM   3618 N  NE2 . GLN   D 1 102 ? -10.029 -46.285 -35.531 1.000 46.373  0  212 GLN   C NE2 1 ? 
ATOM   3619 N  N   . ARG   D 1 103 ? -16.411 -48.800 -35.686 1.000 31.628  0  213 ARG   C N   1 ? 
ATOM   3620 C  CA  . ARG   D 1 103 ? -17.182 -50.020 -35.517 1.000 35.538  0  213 ARG   C CA  1 ? 
ATOM   3621 C  C   . ARG   D 1 103 ? -18.440 -49.985 -36.392 1.000 34.545  0  213 ARG   C C   1 ? 
ATOM   3622 O  O   . ARG   D 1 103 ? -18.955 -51.032 -36.757 1.000 35.824  0  213 ARG   C O   1 ? 
ATOM   3623 C  CB  . ARG   D 1 103 ? -17.462 -50.266 -34.032 1.000 38.781  0  213 ARG   C CB  1 ? 
ATOM   3624 C  CG  . ARG   D 1 103 ? -16.194 -50.598 -33.250 1.000 44.733  0  213 ARG   C CG  1 ? 
ATOM   3625 C  CD  . ARG   D 1 103 ? -16.458 -50.971 -31.798 1.000 56.626  0  213 ARG   C CD  1 ? 
ATOM   3626 N  NE  . ARG   D 1 103 ? -17.057 -52.305 -31.661 1.000 64.787  0  213 ARG   C NE  1 ? 
ATOM   3627 C  CZ  . ARG   D 1 103 ? -17.409 -52.874 -30.504 1.000 61.999  0  213 ARG   C CZ  1 ? 
ATOM   3628 N  NH1 . ARG   D 1 103 ? -17.258 -52.219 -29.362 1.000 71.425  0  213 ARG   C NH1 1 ? 
ATOM   3629 N  NH2 . ARG   D 1 103 ? -17.934 -54.089 -30.499 1.000 70.812  0  213 ARG   C NH2 1 ? 
ATOM   3630 N  N   . LEU   D 1 104 ? -18.920 -48.773 -36.730 1.000 33.417  0  214 LEU   C N   1 ? 
ATOM   3631 C  CA  . LEU   D 1 104 ? -19.996 -48.615 -37.706 1.000 34.111  0  214 LEU   C CA  1 ? 
ATOM   3632 C  C   . LEU   D 1 104 ? -19.453 -48.903 -39.109 1.000 34.725  0  214 LEU   C C   1 ? 
ATOM   3633 O  O   . LEU   D 1 104 ? -20.113 -49.567 -39.911 1.000 40.247  0  214 LEU   C O   1 ? 
ATOM   3634 C  CB  . LEU   D 1 104 ? -20.610 -47.214 -37.630 1.000 34.715  0  214 LEU   C CB  1 ? 
ATOM   3635 C  CG  . LEU   D 1 104 ? -21.546 -46.942 -36.443 1.000 38.961  0  214 LEU   C CG  1 ? 
ATOM   3636 C  CD1 . LEU   D 1 104 ? -21.961 -45.479 -36.426 1.000 41.142  0  214 LEU   C CD1 1 ? 
ATOM   3637 C  CD2 . LEU   D 1 104 ? -22.779 -47.840 -36.469 1.000 36.373  0  214 LEU   C CD2 1 ? 
ATOM   3638 N  N   . HIS   D 1 105 ? -18.241 -48.399 -39.388 1.000 31.402  0  215 HIS   C N   1 ? 
ATOM   3639 C  CA  . HIS   D 1 105 ? -17.609 -48.544 -40.694 1.000 33.747  0  215 HIS   C CA  1 ? 
ATOM   3640 C  C   . HIS   D 1 105 ? -17.378 -50.026 -41.006 1.000 36.717  0  215 HIS   C C   1 ? 
ATOM   3641 O  O   . HIS   D 1 105 ? -17.514 -50.446 -42.151 1.000 36.979  0  215 HIS   C O   1 ? 
ATOM   3642 C  CB  . HIS   D 1 105 ? -16.291 -47.758 -40.740 1.000 36.226  0  215 HIS   C CB  1 ? 
ATOM   3643 C  CG  . HIS   D 1 105 ? -15.715 -47.597 -42.105 1.000 37.128  0  215 HIS   C CG  1 ? 
ATOM   3644 N  ND1 . HIS   D 1 105 ? -14.923 -48.549 -42.712 1.000 37.704  0  215 HIS   C ND1 1 ? 
ATOM   3645 C  CD2 . HIS   D 1 105 ? -15.806 -46.580 -42.978 1.000 40.319  0  215 HIS   C CD2 1 ? 
ATOM   3646 C  CE1 . HIS   D 1 105 ? -14.558 -48.113 -43.909 1.000 40.345  0  215 HIS   C CE1 1 ? 
ATOM   3647 N  NE2 . HIS   D 1 105 ? -15.082 -46.919 -44.090 1.000 38.945  0  215 HIS   C NE2 1 ? 
ATOM   3648 N  N   . SER   D 1 106 ? -17.041 -50.807 -39.965 1.000 38.464  0  216 SER   C N   1 ? 
ATOM   3649 C  CA  . SER   D 1 106 ? -16.690 -52.213 -40.126 1.000 42.578  0  216 SER   C CA  1 ? 
ATOM   3650 C  C   . SER   D 1 106 ? -17.857 -53.118 -39.713 1.000 45.578  0  216 SER   C C   1 ? 
ATOM   3651 O  O   . SER   D 1 106 ? -17.691 -54.334 -39.627 1.000 41.765  0  216 SER   C O   1 ? 
ATOM   3652 C  CB  . SER   D 1 106 ? -15.444 -52.546 -39.331 1.000 41.602  0  216 SER   C CB  1 ? 
ATOM   3653 O  OG  . SER   D 1 106 ? -15.675 -52.395 -37.933 1.000 40.897  0  216 SER   C OG  1 ? 
ATOM   3654 N  N   . ASP   D 1 107 ? -19.039 -52.521 -39.483 1.000 47.456  0  217 ASP   C N   1 ? 
ATOM   3655 C  CA  . ASP   D 1 107 ? -20.189 -53.267 -38.991 1.000 45.175  0  217 ASP   C CA  1 ? 
ATOM   3656 C  C   . ASP   D 1 107 ? -20.725 -54.169 -40.103 1.000 49.261  0  217 ASP   C C   1 ? 
ATOM   3657 O  O   . ASP   D 1 107 ? -20.783 -53.764 -41.264 1.000 55.207  0  217 ASP   C O   1 ? 
ATOM   3658 C  CB  . ASP   D 1 107 ? -21.282 -52.340 -38.481 1.000 44.219  0  217 ASP   C CB  1 ? 
ATOM   3659 C  CG  . ASP   D 1 107 ? -22.341 -52.998 -37.605 1.000 43.620  0  217 ASP   C CG  1 ? 
ATOM   3660 O  OD1 . ASP   D 1 107 ? -22.153 -54.183 -37.243 1.000 42.516  0  217 ASP   C OD1 1 ? 
ATOM   3661 O  OD2 . ASP   D 1 107 ? -23.339 -52.320 -37.282 1.000 45.631  0  217 ASP   C OD2 1 ? 
ATOM   3662 N  N   . LYS   D 1 108 ? -21.161 -55.376 -39.715 1.000 57.731  0  218 LYS   C N   1 ? 
ATOM   3663 C  CA  . LYS   D 1 108 ? -21.721 -56.341 -40.647 1.000 58.648  0  218 LYS   C CA  1 ? 
ATOM   3664 C  C   . LYS   D 1 108 ? -23.022 -56.892 -40.063 1.000 55.159  0  218 LYS   C C   1 ? 
ATOM   3665 O  O   . LYS   D 1 108 ? -23.043 -57.356 -38.927 1.000 63.155  0  218 LYS   C O   1 ? 
ATOM   3666 C  CB  . LYS   D 1 108 ? -20.714 -57.469 -40.911 1.000 66.197  0  218 LYS   C CB  1 ? 
ATOM   3667 C  CG  . LYS   D 1 108 ? -19.299 -57.007 -41.266 1.000 75.387  0  218 LYS   C CG  1 ? 
ATOM   3668 C  CD  . LYS   D 1 108 ? -19.191 -56.233 -42.577 1.000 91.436  0  218 LYS   C CD  1 ? 
ATOM   3669 C  CE  . LYS   D 1 108 ? -17.934 -55.420 -42.658 1.000 99.431  0  218 LYS   C CE  1 ? 
ATOM   3670 N  NZ  . LYS   D 1 108 ? -17.794 -54.751 -43.954 1.000 98.091  0  218 LYS   C NZ  1 ? 
ATOM   3671 N  N   . GLY   D 1 109 ? -24.117 -56.763 -40.828 1.000 56.229  0  219 GLY   C N   1 ? 
ATOM   3672 C  CA  . GLY   D 1 109 ? -25.419 -57.277 -40.417 1.000 50.922  0  219 GLY   C CA  1 ? 
ATOM   3673 C  C   . GLY   D 1 109 ? -26.083 -56.389 -39.358 1.000 47.299  0  219 GLY   C C   1 ? 
ATOM   3674 O  O   . GLY   D 1 109 ? -27.028 -56.815 -38.701 1.000 57.885  0  219 GLY   C O   1 ? 
ATOM   3675 N  N   . GLY   D 1 110 ? -25.578 -55.153 -39.207 1.000 50.384  0  220 GLY   C N   1 ? 
ATOM   3676 C  CA  . GLY   D 1 110 ? -26.142 -54.183 -38.274 1.000 51.902  0  220 GLY   C CA  1 ? 
ATOM   3677 C  C   . GLY   D 1 110 ? -26.010 -54.634 -36.815 1.000 53.585  0  220 GLY   C C   1 ? 
ATOM   3678 O  O   . GLY   D 1 110 ? -26.820 -54.250 -35.971 1.000 53.346  0  220 GLY   C O   1 ? 
ATOM   3679 N  N   . SER   D 1 111 ? -24.944 -55.392 -36.520 1.000 52.250  0  221 SER   C N   1 ? 
ATOM   3680 C  CA  . SER   D 1 111 ? -24.740 -55.961 -35.193 1.000 50.142  0  221 SER   C CA  1 ? 
ATOM   3681 C  C   . SER   D 1 111 ? -24.404 -54.857 -34.185 1.000 39.815  0  221 SER   C C   1 ? 
ATOM   3682 O  O   . SER   D 1 111 ? -25.092 -54.701 -33.183 1.000 38.456  0  221 SER   C O   1 ? 
ATOM   3683 C  CB  . SER   D 1 111 ? -23.670 -57.020 -35.220 1.000 49.039  0  221 SER   C CB  1 ? 
ATOM   3684 O  OG  . SER   D 1 111 ? -23.446 -57.547 -33.922 1.000 49.752  0  221 SER   C OG  1 ? 
ATOM   3685 N  N   . PHE   D 1 112 ? -23.337 -54.103 -34.466 1.000 36.310  0  222 PHE   C N   1 ? 
ATOM   3686 C  CA  . PHE   D 1 112 ? -22.894 -53.030 -33.585 1.000 37.645  0  222 PHE   C CA  1 ? 
ATOM   3687 C  C   . PHE   D 1 112 ? -23.929 -51.901 -33.580 1.000 39.401  0  222 PHE   C C   1 ? 
ATOM   3688 O  O   . PHE   D 1 112 ? -24.088 -51.206 -32.576 1.000 40.455  0  222 PHE   C O   1 ? 
ATOM   3689 C  CB  . PHE   D 1 112 ? -21.515 -52.526 -34.015 1.000 37.930  0  222 PHE   C CB  1 ? 
ATOM   3690 C  CG  . PHE   D 1 112 ? -21.035 -51.311 -33.237 1.000 44.924  0  222 PHE   C CG  1 ? 
ATOM   3691 C  CD1 . PHE   D 1 112 ? -20.459 -51.452 -31.976 1.000 49.329  0  222 PHE   C CD1 1 ? 
ATOM   3692 C  CD2 . PHE   D 1 112 ? -21.179 -50.025 -33.759 1.000 41.378  0  222 PHE   C CD2 1 ? 
ATOM   3693 C  CE1 . PHE   D 1 112 ? -20.031 -50.337 -31.264 1.000 52.548  0  222 PHE   C CE1 1 ? 
ATOM   3694 C  CE2 . PHE   D 1 112 ? -20.755 -48.916 -33.040 1.000 40.328  0  222 PHE   C CE2 1 ? 
ATOM   3695 C  CZ  . PHE   D 1 112 ? -20.181 -49.073 -31.795 1.000 47.456  0  222 PHE   C CZ  1 ? 
ATOM   3696 N  N   . GLU   D 1 113 ? -24.601 -51.712 -34.725 1.000 37.819  0  223 GLU   C N   1 ? 
ATOM   3697 C  CA  . GLU   D 1 113 ? -25.639 -50.698 -34.873 1.000 36.862  0  223 GLU   C CA  1 ? 
ATOM   3698 C  C   . GLU   D 1 113 ? -26.742 -50.930 -33.835 1.000 35.362  0  223 GLU   C C   1 ? 
ATOM   3699 O  O   . GLU   D 1 113 ? -27.190 -49.993 -33.181 1.000 36.335  0  223 GLU   C O   1 ? 
ATOM   3700 C  CB  . GLU   D 1 113 ? -26.192 -50.765 -36.302 1.000 35.753  0  223 GLU   C CB  1 ? 
ATOM   3701 C  CG  . GLU   D 1 113 ? -27.167 -49.648 -36.651 1.000 35.699  0  223 GLU   C CG  1 ? 
ATOM   3702 C  CD  . GLU   D 1 113 ? -27.752 -49.778 -38.048 1.000 40.197  0  223 GLU   C CD  1 ? 
ATOM   3703 O  OE1 . GLU   D 1 113 ? -26.964 -49.919 -39.004 1.000 40.478  0  223 GLU   C OE1 1 ? 
ATOM   3704 O  OE2 . GLU   D 1 113 ? -28.992 -49.741 -38.183 1.000 46.475  0  223 GLU   C OE2 1 ? 
ATOM   3705 N  N   . ALA   D 1 114 ? -27.165 -52.195 -33.697 1.000 38.403  0  224 ALA   C N   1 ? 
ATOM   3706 C  CA  . ALA   D 1 114 ? -28.251 -52.565 -32.798 1.000 37.704  0  224 ALA   C CA  1 ? 
ATOM   3707 C  C   . ALA   D 1 114 ? -27.815 -52.411 -31.338 1.000 35.266  0  224 ALA   C C   1 ? 
ATOM   3708 O  O   . ALA   D 1 114 ? -28.623 -52.062 -30.484 1.000 38.178  0  224 ALA   C O   1 ? 
ATOM   3709 C  CB  . ALA   D 1 114 ? -28.699 -53.985 -33.095 1.000 37.161  0  224 ALA   C CB  1 ? 
ATOM   3710 N  N   . ALA   D 1 115 ? -26.538 -52.705 -31.063 1.000 36.846  0  225 ALA   C N   1 ? 
ATOM   3711 C  CA  . ALA   D 1 115 ? -25.993 -52.612 -29.715 1.000 38.526  0  225 ALA   C CA  1 ? 
ATOM   3712 C  C   . ALA   D 1 115 ? -25.952 -51.152 -29.266 1.000 39.286  0  225 ALA   C C   1 ? 
ATOM   3713 O  O   . ALA   D 1 115 ? -26.177 -50.855 -28.096 1.000 47.350  0  225 ALA   C O   1 ? 
ATOM   3714 C  CB  . ALA   D 1 115 ? -24.615 -53.244 -29.666 1.000 40.340  0  225 ALA   C CB  1 ? 
ATOM   3715 N  N   . LEU   D 1 116 ? -25.655 -50.251 -30.211 1.000 46.311  0  226 LEU   C N   1 ? 
ATOM   3716 C  CA  . LEU   D 1 116 ? -25.561 -48.826 -29.923 1.000 39.227  0  226 LEU   C CA  1 ? 
ATOM   3717 C  C   . LEU   D 1 116 ? -26.944 -48.290 -29.536 1.000 38.372  0  226 LEU   C C   1 ? 
ATOM   3718 O  O   . LEU   D 1 116 ? -27.073 -47.531 -28.579 1.000 40.583  0  226 LEU   C O   1 ? 
ATOM   3719 C  CB  . LEU   D 1 116 ? -24.990 -48.103 -31.142 1.000 40.546  0  226 LEU   C CB  1 ? 
ATOM   3720 C  CG  . LEU   D 1 116 ? -24.441 -46.696 -30.896 1.000 47.889  0  226 LEU   C CG  1 ? 
ATOM   3721 C  CD1 . LEU   D 1 116 ? -23.215 -46.742 -30.000 1.000 43.869  0  226 LEU   C CD1 1 ? 
ATOM   3722 C  CD2 . LEU   D 1 116 ? -24.115 -46.007 -32.211 1.000 54.590  0  226 LEU   C CD2 1 ? 
ATOM   3723 N  N   . TRP   D 1 117 ? -27.976 -48.722 -30.276 1.000 33.489  0  227 TRP   C N   1 ? 
ATOM   3724 C  CA  . TRP   D 1 117 ? -29.356 -48.379 -29.960 1.000 37.358  0  227 TRP   C CA  1 ? 
ATOM   3725 C  C   . TRP   D 1 117 ? -29.700 -48.811 -28.527 1.000 41.579  0  227 TRP   C C   1 ? 
ATOM   3726 O  O   . TRP   D 1 117 ? -30.361 -48.076 -27.798 1.000 37.970  0  227 TRP   C O   1 ? 
ATOM   3727 C  CB  . TRP   D 1 117 ? -30.307 -49.029 -30.980 1.000 38.259  0  227 TRP   C CB  1 ? 
ATOM   3728 C  CG  . TRP   D 1 117 ? -31.769 -48.825 -30.676 1.000 35.942  0  227 TRP   C CG  1 ? 
ATOM   3729 C  CD1 . TRP   D 1 117 ? -32.602 -49.689 -30.028 1.000 34.770  0  227 TRP   C CD1 1 ? 
ATOM   3730 C  CD2 . TRP   D 1 117 ? -32.560 -47.657 -30.977 1.000 35.163  0  227 TRP   C CD2 1 ? 
ATOM   3731 N  NE1 . TRP   D 1 117 ? -33.860 -49.151 -29.922 1.000 35.299  0  227 TRP   C NE1 1 ? 
ATOM   3732 C  CE2 . TRP   D 1 117 ? -33.865 -47.905 -30.491 1.000 35.737  0  227 TRP   C CE2 1 ? 
ATOM   3733 C  CE3 . TRP   D 1 117 ? -32.300 -46.440 -31.615 1.000 35.434  0  227 TRP   C CE3 1 ? 
ATOM   3734 C  CZ2 . TRP   D 1 117 ? -34.896 -46.977 -30.618 1.000 38.549  0  227 TRP   C CZ2 1 ? 
ATOM   3735 C  CZ3 . TRP   D 1 117 ? -33.320 -45.519 -31.735 1.000 40.139  0  227 TRP   C CZ3 1 ? 
ATOM   3736 C  CH2 . TRP   D 1 117 ? -34.599 -45.784 -31.238 1.000 39.147  0  227 TRP   C CH2 1 ? 
ATOM   3737 N  N   . GLN   D 1 118 ? -29.213 -50.000 -28.136 1.000 47.898  0  228 GLN   C N   1 ? 
ATOM   3738 C  CA  . GLN   D 1 118 ? -29.559 -50.617 -26.858 1.000 51.553  0  228 GLN   C CA  1 ? 
ATOM   3739 C  C   . GLN   D 1 118 ? -28.920 -49.851 -25.695 1.000 51.399  0  228 GLN   C C   1 ? 
ATOM   3740 O  O   . GLN   D 1 118 ? -29.601 -49.521 -24.726 1.000 53.745  0  228 GLN   C O   1 ? 
ATOM   3741 C  CB  . GLN   D 1 118 ? -29.102 -52.081 -26.853 1.000 59.118  0  228 GLN   C CB  1 ? 
ATOM   3742 C  CG  . GLN   D 1 118 ? -29.274 -52.791 -25.512 1.000 66.562  0  228 GLN   C CG  1 ? 
ATOM   3743 C  CD  . GLN   D 1 118 ? -28.746 -54.212 -25.516 1.000 76.382  0  228 GLN   C CD  1 ? 
ATOM   3744 O  OE1 . GLN   D 1 118 ? -28.282 -54.729 -26.540 1.000 72.895  0  228 GLN   C OE1 1 ? 
ATOM   3745 N  NE2 . GLN   D 1 118 ? -28.811 -54.859 -24.360 1.000 78.335  0  228 GLN   C NE2 1 ? 
ATOM   3746 N  N   . GLN   D 1 119 ? -27.599 -49.623 -25.782 1.000 46.389  0  229 GLN   C N   1 ? 
ATOM   3747 C  CA  . GLN   D 1 119 ? -26.821 -49.120 -24.652 1.000 44.489  0  229 GLN   C CA  1 ? 
ATOM   3748 C  C   . GLN   D 1 119 ? -26.965 -47.604 -24.504 1.000 45.314  0  229 GLN   C C   1 ? 
ATOM   3749 O  O   . GLN   D 1 119 ? -26.893 -47.090 -23.392 1.000 51.937  0  229 GLN   C O   1 ? 
ATOM   3750 C  CB  . GLN   D 1 119 ? -25.344 -49.498 -24.765 1.000 53.722  0  229 GLN   C CB  1 ? 
ATOM   3751 C  CG  . GLN   D 1 119 ? -24.983 -50.804 -24.066 1.000 67.955  0  229 GLN   C CG  1 ? 
ATOM   3752 C  CD  . GLN   D 1 119 ? -23.493 -51.072 -24.051 1.000 77.626  0  229 GLN   C CD  1 ? 
ATOM   3753 O  OE1 . GLN   D 1 119 ? -22.872 -51.309 -25.093 1.000 82.527  0  229 GLN   C OE1 1 ? 
ATOM   3754 N  NE2 . GLN   D 1 119 ? -22.901 -51.041 -22.863 1.000 78.065  0  229 GLN   C NE2 1 ? 
ATOM   3755 N  N   . TRP   D 1 120 ? -27.083 -46.888 -25.630 1.000 47.641  0  230 TRP   C N   1 ? 
ATOM   3756 C  CA  . TRP   D 1 120 ? -27.148 -45.432 -25.599 1.000 53.222  0  230 TRP   C CA  1 ? 
ATOM   3757 C  C   . TRP   D 1 120 ? -28.568 -44.966 -25.299 1.000 49.973  0  230 TRP   C C   1 ? 
ATOM   3758 O  O   . TRP   D 1 120 ? -29.535 -45.540 -25.793 1.000 51.384  0  230 TRP   C O   1 ? 
ATOM   3759 C  CB  . TRP   D 1 120 ? -26.641 -44.835 -26.918 1.000 53.255  0  230 TRP   C CB  1 ? 
ATOM   3760 C  CG  . TRP   D 1 120 ? -25.142 -44.785 -27.028 1.000 53.814  0  230 TRP   C CG  1 ? 
ATOM   3761 C  CD1 . TRP   D 1 120 ? -24.233 -45.490 -26.293 1.000 55.324  0  230 TRP   C CD1 1 ? 
ATOM   3762 C  CD2 . TRP   D 1 120 ? -24.379 -44.003 -27.966 1.000 55.674  0  230 TRP   C CD2 1 ? 
ATOM   3763 N  NE1 . TRP   D 1 120 ? -22.959 -45.176 -26.684 1.000 52.738  0  230 TRP   C NE1 1 ? 
ATOM   3764 C  CE2 . TRP   D 1 120 ? -23.015 -44.275 -27.715 1.000 50.189  0  230 TRP   C CE2 1 ? 
ATOM   3765 C  CE3 . TRP   D 1 120 ? -24.711 -43.105 -28.988 1.000 55.386  0  230 TRP   C CE3 1 ? 
ATOM   3766 C  CZ2 . TRP   D 1 120 ? -21.992 -43.681 -28.449 1.000 53.088  0  230 TRP   C CZ2 1 ? 
ATOM   3767 C  CZ3 . TRP   D 1 120 ? -23.697 -42.521 -29.717 1.000 59.987  0  230 TRP   C CZ3 1 ? 
ATOM   3768 C  CH2 . TRP   D 1 120 ? -22.357 -42.808 -29.450 1.000 54.773  0  230 TRP   C CH2 1 ? 
ATOM   3769 N  N   . ASP   D 1 121 ? -28.671 -43.914 -24.476 1.000 55.680  0  231 ASP   C N   1 ? 
ATOM   3770 C  CA  . ASP   D 1 121 ? -29.942 -43.270 -24.195 1.000 57.320  0  231 ASP   C CA  1 ? 
ATOM   3771 C  C   . ASP   D 1 121 ? -30.355 -42.448 -25.412 1.000 45.560  0  231 ASP   C C   1 ? 
ATOM   3772 O  O   . ASP   D 1 121 ? -29.535 -42.156 -26.278 1.000 52.101  0  231 ASP   C O   1 ? 
ATOM   3773 C  CB  . ASP   D 1 121 ? -29.868 -42.410 -22.942 1.000 57.071  0  231 ASP   C CB  1 ? 
ATOM   3774 C  CG  . ASP   D 1 121 ? -28.811 -41.315 -22.965 1.000 64.202  0  231 ASP   C CG  1 ? 
ATOM   3775 O  OD1 . ASP   D 1 121 ? -27.615 -41.656 -22.857 1.000 80.576  0  231 ASP   C OD1 1 ? 
ATOM   3776 O  OD2 . ASP   D 1 121 ? -29.186 -40.144 -23.176 1.000 78.945  0  231 ASP   C OD2 1 ? 
ATOM   3777 N  N   . ARG   D 1 122 ? -31.617 -42.023 -25.421 1.000 46.495  0  232 ARG   C N   1 ? 
ATOM   3778 C  CA  . ARG   D 1 122 ? -32.196 -41.320 -26.553 1.000 54.015  0  232 ARG   C CA  1 ? 
ATOM   3779 C  C   . ARG   D 1 122 ? -31.418 -40.028 -26.837 1.000 56.429  0  232 ARG   C C   1 ? 
ATOM   3780 O  O   . ARG   D 1 122 ? -31.104 -39.734 -27.991 1.000 50.506  0  232 ARG   C O   1 ? 
ATOM   3781 C  CB  . ARG   D 1 122 ? -33.678 -41.059 -26.270 1.000 51.706  0  232 ARG   C CB  1 ? 
ATOM   3782 C  CG  . ARG   D 1 122 ? -34.389 -40.213 -27.313 1.000 56.394  0  232 ARG   C CG  1 ? 
ATOM   3783 C  CD  . ARG   D 1 122 ? -35.889 -40.259 -27.140 1.000 55.056  0  232 ARG   C CD  1 ? 
ATOM   3784 N  NE  . ARG   D 1 122 ? -36.537 -39.154 -27.850 1.000 54.849  0  232 ARG   C NE  1 ? 
ATOM   3785 C  CZ  . ARG   D 1 122 ? -37.248 -39.261 -28.969 1.000 65.315  0  232 ARG   C CZ  1 ? 
ATOM   3786 N  NH1 . ARG   D 1 122 ? -37.359 -40.428 -29.587 1.000 60.405  0  232 ARG   C NH1 1 ? 
ATOM   3787 N  NH2 . ARG   D 1 122 ? -37.814 -38.187 -29.489 1.000 69.688  0  232 ARG   C NH2 1 ? 
ATOM   3788 N  N   . GLN   D 1 123 ? -31.076 -39.286 -25.774 1.000 50.800  0  233 GLN   C N   1 ? 
ATOM   3789 C  CA  . GLN   D 1 123 ? -30.477 -37.964 -25.922 1.000 57.782  0  233 GLN   C CA  1 ? 
ATOM   3790 C  C   . GLN   D 1 123 ? -29.059 -38.096 -26.495 1.000 55.422  0  233 GLN   C C   1 ? 
ATOM   3791 O  O   . GLN   D 1 123 ? -28.658 -37.305 -27.349 1.000 47.400  0  233 GLN   C O   1 ? 
ATOM   3792 C  CB  . GLN   D 1 123 ? -30.490 -37.216 -24.587 1.000 61.957  0  233 GLN   C CB  1 ? 
ATOM   3793 C  CG  . GLN   D 1 123 ? -30.534 -35.695 -24.728 1.000 73.219  0  233 GLN   C CG  1 ? 
ATOM   3794 C  CD  . GLN   D 1 123 ? -31.813 -35.193 -25.372 1.000 84.876  0  233 GLN   C CD  1 ? 
ATOM   3795 O  OE1 . GLN   D 1 123 ? -31.792 -34.529 -26.414 1.000 90.651  0  233 GLN   C OE1 1 ? 
ATOM   3796 N  NE2 . GLN   D 1 123 ? -32.943 -35.509 -24.754 1.000 91.058  0  233 GLN   C NE2 1 ? 
ATOM   3797 N  N   . SER   D 1 124 ? -28.313 -39.111 -26.025 1.000 52.320  0  234 SER   C N   1 ? 
ATOM   3798 C  CA  . SER   D 1 124 ? -26.974 -39.392 -26.535 1.000 49.593  0  234 SER   C CA  1 ? 
ATOM   3799 C  C   . SER   D 1 124 ? -27.032 -39.714 -28.028 1.000 46.956  0  234 SER   C C   1 ? 
ATOM   3800 O  O   . SER   D 1 124 ? -26.146 -39.325 -28.784 1.000 52.758  0  234 SER   C O   1 ? 
ATOM   3801 C  CB  . SER   D 1 124 ? -26.318 -40.520 -25.769 1.000 47.327  0  234 SER   C CB  1 ? 
ATOM   3802 O  OG  . SER   D 1 124 ? -25.991 -40.121 -24.448 1.000 51.652  0  234 SER   C OG  1 ? 
ATOM   3803 N  N   . LEU   D 1 125 ? -28.082 -40.435 -28.434 1.000 44.640  0  235 LEU   C N   1 ? 
ATOM   3804 C  CA  . LEU   D 1 125 ? -28.228 -40.881 -29.810 1.000 46.184  0  235 LEU   C CA  1 ? 
ATOM   3805 C  C   . LEU   D 1 125 ? -28.562 -39.681 -30.703 1.000 42.939  0  235 LEU   C C   1 ? 
ATOM   3806 O  O   . LEU   D 1 125 ? -28.010 -39.543 -31.791 1.000 42.079  0  235 LEU   C O   1 ? 
ATOM   3807 C  CB  . LEU   D 1 125 ? -29.313 -41.957 -29.879 1.000 48.525  0  235 LEU   C CB  1 ? 
ATOM   3808 C  CG  . LEU   D 1 125 ? -29.153 -42.998 -30.989 1.000 60.137  0  235 LEU   C CG  1 ? 
ATOM   3809 C  CD1 . LEU   D 1 125 ? -28.059 -44.003 -30.636 1.000 57.685  0  235 LEU   C CD1 1 ? 
ATOM   3810 C  CD2 . LEU   D 1 125 ? -30.457 -43.706 -31.266 1.000 62.591  0  235 LEU   C CD2 1 ? 
ATOM   3811 N  N   . ILE   D 1 126 ? -29.444 -38.801 -30.206 1.000 39.805  0  236 ILE   C N   1 ? 
ATOM   3812 C  CA  . ILE   D 1 126 ? -29.924 -37.652 -30.969 1.000 40.914  0  236 ILE   C CA  1 ? 
ATOM   3813 C  C   . ILE   D 1 126 ? -28.764 -36.696 -31.255 1.000 39.566  0  236 ILE   C C   1 ? 
ATOM   3814 O  O   . ILE   D 1 126 ? -28.620 -36.215 -32.377 1.000 39.992  0  236 ILE   C O   1 ? 
ATOM   3815 C  CB  . ILE   D 1 126 ? -31.078 -36.952 -30.225 1.000 41.687  0  236 ILE   C CB  1 ? 
ATOM   3816 C  CG1 . ILE   D 1 126 ? -32.360 -37.788 -30.284 1.000 44.052  0  236 ILE   C CG1 1 ? 
ATOM   3817 C  CG2 . ILE   D 1 126 ? -31.305 -35.535 -30.763 1.000 38.728  0  236 ILE   C CG2 1 ? 
ATOM   3818 C  CD1 . ILE   D 1 126 ? -33.413 -37.383 -29.269 1.000 46.956  0  236 ILE   C CD1 1 ? 
ATOM   3819 N  N   . MET   D 1 127 ? -27.971 -36.391 -30.220 1.000 38.880  0  237 MET   C N   1 ? 
ATOM   3820 C  CA  . MET   D 1 127 ? -26.854 -35.469 -30.355 1.000 40.569  0  237 MET   C CA  1 ? 
ATOM   3821 C  C   . MET   D 1 127 ? -25.837 -36.015 -31.361 1.000 39.876  0  237 MET   C C   1 ? 
ATOM   3822 O  O   . MET   D 1 127 ? -25.283 -35.255 -32.154 1.000 40.182  0  237 MET   C O   1 ? 
ATOM   3823 C  CB  . MET   D 1 127 ? -26.179 -35.215 -29.002 1.000 48.724  0  237 MET   C CB  1 ? 
ATOM   3824 C  CG  . MET   D 1 127 ? -26.918 -34.211 -28.131 1.000 57.787  0  237 MET   C CG  1 ? 
ATOM   3825 S  SD  . MET   D 1 127 ? -26.152 -33.971 -26.517 1.000 68.512  0  237 MET   C SD  1 ? 
ATOM   3826 C  CE  . MET   D 1 127 ? -26.547 -35.524 -25.704 1.000 65.191  0  237 MET   C CE  1 ? 
ATOM   3827 N  N   . PHE   D 1 128 ? -25.613 -37.338 -31.330 1.000 37.094  0  238 PHE   C N   1 ? 
ATOM   3828 C  CA  . PHE   D 1 128 ? -24.644 -37.974 -32.213 1.000 41.687  0  238 PHE   C CA  1 ? 
ATOM   3829 C  C   . PHE   D 1 128 ? -25.145 -37.904 -33.656 1.000 35.668  0  238 PHE   C C   1 ? 
ATOM   3830 O  O   . PHE   D 1 128 ? -24.401 -37.520 -34.551 1.000 37.212  0  238 PHE   C O   1 ? 
ATOM   3831 C  CB  . PHE   D 1 128 ? -24.387 -39.424 -31.793 1.000 44.392  0  238 PHE   C CB  1 ? 
ATOM   3832 C  CG  . PHE   D 1 128 ? -23.171 -40.054 -32.459 1.000 42.800  0  238 PHE   C CG  1 ? 
ATOM   3833 C  CD1 . PHE   D 1 128 ? -23.271 -40.654 -33.714 1.000 43.289  0  238 PHE   C CD1 1 ? 
ATOM   3834 C  CD2 . PHE   D 1 128 ? -21.922 -40.028 -31.837 1.000 45.864  0  238 PHE   C CD2 1 ? 
ATOM   3835 C  CE1 . PHE   D 1 128 ? -22.154 -41.206 -34.327 1.000 48.067  0  238 PHE   C CE1 1 ? 
ATOM   3836 C  CE2 . PHE   D 1 128 ? -20.809 -40.584 -32.455 1.000 49.274  0  238 PHE   C CE2 1 ? 
ATOM   3837 C  CZ  . PHE   D 1 128 ? -20.928 -41.173 -33.696 1.000 50.602  0  238 PHE   C CZ  1 ? 
ATOM   3838 N  N   . ILE   D 1 129 ? -26.413 -38.292 -33.863 1.000 32.240  0  239 ILE   C N   1 ? 
ATOM   3839 C  CA  . ILE   D 1 129 ? -27.027 -38.288 -35.187 1.000 31.451  0  239 ILE   C CA  1 ? 
ATOM   3840 C  C   . ILE   D 1 129 ? -26.967 -36.873 -35.771 1.000 32.367  0  239 ILE   C C   1 ? 
ATOM   3841 O  O   . ILE   D 1 129 ? -26.486 -36.682 -36.887 1.000 32.619  0  239 ILE   C O   1 ? 
ATOM   3842 C  CB  . ILE   D 1 129 ? -28.471 -38.828 -35.119 1.000 31.550  0  239 ILE   C CB  1 ? 
ATOM   3843 C  CG1 . ILE   D 1 129 ? -28.490 -40.325 -34.781 1.000 31.555  0  239 ILE   C CG1 1 ? 
ATOM   3844 C  CG2 . ILE   D 1 129 ? -29.233 -38.538 -36.419 1.000 33.055  0  239 ILE   C CG2 1 ? 
ATOM   3845 C  CD1 . ILE   D 1 129 ? -29.842 -40.846 -34.334 1.000 31.655  0  239 ILE   C CD1 1 ? 
ATOM   3846 N  N   . THR   D 1 130 ? -27.469 -35.892 -35.005 1.000 33.390  0  240 THR   C N   1 ? 
ATOM   3847 C  CA  . THR   D 1 130 ? -27.492 -34.499 -35.439 1.000 36.185  0  240 THR   C CA  1 ? 
ATOM   3848 C  C   . THR   D 1 130 ? -26.078 -34.063 -35.826 1.000 38.166  0  240 THR   C C   1 ? 
ATOM   3849 O  O   . THR   D 1 130 ? -25.886 -33.425 -36.856 1.000 43.219  0  240 THR   C O   1 ? 
ATOM   3850 C  CB  . THR   D 1 130 ? -28.070 -33.620 -34.327 1.000 39.255  0  240 THR   C CB  1 ? 
ATOM   3851 O  OG1 . THR   D 1 130 ? -29.371 -34.139 -34.078 1.000 49.844  0  240 THR   C OG1 1 ? 
ATOM   3852 C  CG2 . THR   D 1 130 ? -28.169 -32.156 -34.720 1.000 38.193  0  240 THR   C CG2 1 ? 
ATOM   3853 N  N   . ALA   D 1 131 ? -25.094 -34.431 -34.992 1.000 36.366  0  241 ALA   C N   1 ? 
ATOM   3854 C  CA  . ALA   D 1 131 ? -23.702 -34.076 -35.233 1.000 37.843  0  241 ALA   C CA  1 ? 
ATOM   3855 C  C   . ALA   D 1 131 ? -23.224 -34.672 -36.559 1.000 36.273  0  241 ALA   C C   1 ? 
ATOM   3856 O  O   . ALA   D 1 131 ? -22.660 -33.968 -37.382 1.000 35.545  0  241 ALA   C O   1 ? 
ATOM   3857 C  CB  . ALA   D 1 131 ? -22.838 -34.539 -34.078 1.000 38.617  0  241 ALA   C CB  1 ? 
ATOM   3858 N  N   . PHE   D 1 132 ? -23.497 -35.966 -36.767 1.000 35.605  0  242 PHE   C N   1 ? 
ATOM   3859 C  CA  . PHE   D 1 132 ? -22.991 -36.681 -37.932 1.000 40.799  0  242 PHE   C CA  1 ? 
ATOM   3860 C  C   . PHE   D 1 132 ? -23.577 -36.093 -39.220 1.000 36.433  0  242 PHE   C C   1 ? 
ATOM   3861 O  O   . PHE   D 1 132 ? -22.839 -35.811 -40.159 1.000 33.335  0  242 PHE   C O   1 ? 
ATOM   3862 C  CB  . PHE   D 1 132 ? -23.298 -38.180 -37.849 1.000 38.239  0  242 PHE   C CB  1 ? 
ATOM   3863 C  CG  . PHE   D 1 132 ? -22.885 -38.951 -39.094 1.000 33.797  0  242 PHE   C CG  1 ? 
ATOM   3864 C  CD1 . PHE   D 1 132 ? -21.555 -39.306 -39.305 1.000 32.294  0  242 PHE   C CD1 1 ? 
ATOM   3865 C  CD2 . PHE   D 1 132 ? -23.816 -39.276 -40.075 1.000 36.891  0  242 PHE   C CD2 1 ? 
ATOM   3866 C  CE1 . PHE   D 1 132 ? -21.176 -39.980 -40.454 1.000 33.565  0  242 PHE   C CE1 1 ? 
ATOM   3867 C  CE2 . PHE   D 1 132 ? -23.430 -39.957 -41.220 1.000 35.306  0  242 PHE   C CE2 1 ? 
ATOM   3868 C  CZ  . PHE   D 1 132 ? -22.116 -40.314 -41.403 1.000 34.439  0  242 PHE   C CZ  1 ? 
ATOM   3869 N  N   . LEU   D 1 133 ? -24.910 -35.958 -39.269 1.000 38.706  0  243 LEU   C N   1 ? 
ATOM   3870 C  CA  . LEU   D 1 133 ? -25.605 -35.585 -40.500 1.000 44.415  0  243 LEU   C CA  1 ? 
ATOM   3871 C  C   . LEU   D 1 133 ? -25.101 -34.232 -41.013 1.000 49.575  0  243 LEU   C C   1 ? 
ATOM   3872 O  O   . LEU   D 1 133 ? -24.995 -34.032 -42.221 1.000 63.700  0  243 LEU   C O   1 ? 
ATOM   3873 C  CB  . LEU   D 1 133 ? -27.116 -35.575 -40.271 1.000 39.614  0  243 LEU   C CB  1 ? 
ATOM   3874 C  CG  . LEU   D 1 133 ? -27.773 -36.943 -40.056 1.000 37.925  0  243 LEU   C CG  1 ? 
ATOM   3875 C  CD1 . LEU   D 1 133 ? -29.232 -36.774 -39.694 1.000 44.195  0  243 LEU   C CD1 1 ? 
ATOM   3876 C  CD2 . LEU   D 1 133 ? -27.632 -37.833 -41.282 1.000 39.112  0  243 LEU   C CD2 1 ? 
ATOM   3877 N  N   . ASN   D 1 134 ? -24.793 -33.315 -40.088 1.000 47.014  0  244 ASN   C N   1 ? 
ATOM   3878 C  CA  . ASN   D 1 134 ? -24.301 -31.986 -40.444 1.000 53.969  0  244 ASN   C CA  1 ? 
ATOM   3879 C  C   . ASN   D 1 134 ? -22.828 -32.063 -40.873 1.000 48.958  0  244 ASN   C C   1 ? 
ATOM   3880 O  O   . ASN   D 1 134 ? -22.403 -31.343 -41.775 1.000 61.139  0  244 ASN   C O   1 ? 
ATOM   3881 C  CB  . ASN   D 1 134 ? -24.514 -30.995 -39.304 1.000 49.177  0  244 ASN   C CB  1 ? 
ATOM   3882 C  CG  . ASN   D 1 134 ? -25.949 -30.517 -39.234 1.000 50.790  0  244 ASN   C CG  1 ? 
ATOM   3883 O  OD1 . ASN   D 1 134 ? -26.374 -29.707 -40.066 1.000 46.918  0  244 ASN   C OD1 1 ? 
ATOM   3884 N  ND2 . ASN   D 1 134 ? -26.699 -30.978 -38.244 1.000 49.575  0  244 ASN   C ND2 1 ? 
ATOM   3885 N  N   . ILE   D 1 135 ? -22.073 -32.955 -40.231 1.000 42.555  0  245 ILE   C N   1 ? 
ATOM   3886 C  CA  . ILE   D 1 135 ? -20.643 -33.095 -40.474 1.000 42.542  0  245 ILE   C CA  1 ? 
ATOM   3887 C  C   . ILE   D 1 135 ? -20.407 -33.793 -41.821 1.000 42.806  0  245 ILE   C C   1 ? 
ATOM   3888 O  O   . ILE   D 1 135 ? -19.542 -33.382 -42.589 1.000 36.772  0  245 ILE   C O   1 ? 
ATOM   3889 C  CB  . ILE   D 1 135 ? -19.984 -33.864 -39.311 1.000 49.659  0  245 ILE   C CB  1 ? 
ATOM   3890 C  CG1 . ILE   D 1 135 ? -20.065 -33.083 -37.996 1.000 49.692  0  245 ILE   C CG1 1 ? 
ATOM   3891 C  CG2 . ILE   D 1 135 ? -18.547 -34.247 -39.646 1.000 58.370  0  245 ILE   C CG2 1 ? 
ATOM   3892 C  CD1 . ILE   D 1 135 ? -19.067 -31.957 -37.878 1.000 52.909  0  245 ILE   C CD1 1 ? 
ATOM   3893 N  N   . ALA   D 1 136 ? -21.197 -34.843 -42.093 1.000 47.470  0  246 ALA   C N   1 ? 
ATOM   3894 C  CA  . ALA   D 1 136 ? -20.944 -35.751 -43.209 1.000 47.592  0  246 ALA   C CA  1 ? 
ATOM   3895 C  C   . ALA   D 1 136 ? -21.064 -35.034 -44.560 1.000 43.357  0  246 ALA   C C   1 ? 
ATOM   3896 O  O   . ALA   D 1 136 ? -20.344 -35.365 -45.498 1.000 44.344  0  246 ALA   C O   1 ? 
ATOM   3897 C  CB  . ALA   D 1 136 ? -21.891 -36.927 -43.133 1.000 50.723  0  246 ALA   C CB  1 ? 
ATOM   3898 N  N   . LEU   D 1 137 ? -21.987 -34.070 -44.652 1.000 40.115  0  247 LEU   C N   1 ? 
ATOM   3899 C  CA  . LEU   D 1 137 ? -22.294 -33.406 -45.918 1.000 45.794  0  247 LEU   C CA  1 ? 
ATOM   3900 C  C   . LEU   D 1 137 ? -21.157 -32.461 -46.331 1.000 42.749  0  247 LEU   C C   1 ? 
ATOM   3901 O  O   . LEU   D 1 137 ? -21.047 -32.111 -47.502 1.000 43.481  0  247 LEU   C O   1 ? 
ATOM   3902 C  CB  . LEU   D 1 137 ? -23.619 -32.658 -45.785 1.000 47.901  0  247 LEU   C CB  1 ? 
ATOM   3903 C  CG  . LEU   D 1 137 ? -24.875 -33.532 -45.695 1.000 53.512  0  247 LEU   C CG  1 ? 
ATOM   3904 C  CD1 . LEU   D 1 137 ? -26.045 -32.751 -45.134 1.000 58.648  0  247 LEU   C CD1 1 ? 
ATOM   3905 C  CD2 . LEU   D 1 137 ? -25.229 -34.110 -47.056 1.000 55.090  0  247 LEU   C CD2 1 ? 
ATOM   3906 N  N   . GLN   D 1 138 ? -20.317 -32.060 -45.363 1.000 40.193  0  248 GLN   C N   1 ? 
ATOM   3907 C  CA  . GLN   D 1 138 ? -19.290 -31.051 -45.598 1.000 41.024  0  248 GLN   C CA  1 ? 
ATOM   3908 C  C   . GLN   D 1 138 ? -17.919 -31.708 -45.806 1.000 37.550  0  248 GLN   C C   1 ? 
ATOM   3909 O  O   . GLN   D 1 138 ? -17.046 -31.118 -46.435 1.000 37.246  0  248 GLN   C O   1 ? 
ATOM   3910 C  CB  . GLN   D 1 138 ? -19.226 -30.083 -44.414 1.000 53.998  0  248 GLN   C CB  1 ? 
ATOM   3911 C  CG  . GLN   D 1 138 ? -20.539 -29.357 -44.119 1.000 69.788  0  248 GLN   C CG  1 ? 
ATOM   3912 C  CD  . GLN   D 1 138 ? -20.775 -28.153 -45.008 1.000 83.831  0  248 GLN   C CD  1 ? 
ATOM   3913 O  OE1 . GLN   D 1 138 ? -20.840 -28.258 -46.238 1.000 88.823  0  248 GLN   C OE1 1 ? 
ATOM   3914 N  NE2 . GLN   D 1 138 ? -20.913 -26.988 -44.387 1.000 93.001  0  248 GLN   C NE2 1 ? 
ATOM   3915 N  N   . LEU   D 1 139 ? -17.740 -32.929 -45.272 1.000 39.629  0  249 LEU   C N   1 ? 
ATOM   3916 C  CA  . LEU   D 1 139 ? -16.429 -33.576 -45.247 1.000 40.013  0  249 LEU   C CA  1 ? 
ATOM   3917 C  C   . LEU   D 1 139 ? -16.168 -34.309 -46.562 1.000 40.636  0  249 LEU   C C   1 ? 
ATOM   3918 O  O   . LEU   D 1 139 ? -17.070 -34.935 -47.120 1.000 48.064  0  249 LEU   C O   1 ? 
ATOM   3919 C  CB  . LEU   D 1 139 ? -16.334 -34.543 -44.069 1.000 47.720  0  249 LEU   C CB  1 ? 
ATOM   3920 C  CG  . LEU   D 1 139 ? -16.309 -33.920 -42.673 1.000 57.344  0  249 LEU   C CG  1 ? 
ATOM   3921 C  CD1 . LEU   D 1 139 ? -16.185 -35.026 -41.652 1.000 67.800  0  249 LEU   C CD1 1 ? 
ATOM   3922 C  CD2 . LEU   D 1 139 ? -15.186 -32.905 -42.503 1.000 57.588  0  249 LEU   C CD2 1 ? 
ATOM   3923 N  N   . PRO   D 1 140 ? -14.900 -34.318 -47.053 1.000 43.318  0  250 PRO   C N   1 ? 
ATOM   3924 C  CA  . PRO   D 1 140 ? -14.517 -35.166 -48.183 1.000 41.248  0  250 PRO   C CA  1 ? 
ATOM   3925 C  C   . PRO   D 1 140 ? -14.588 -36.643 -47.800 1.000 41.825  0  250 PRO   C C   1 ? 
ATOM   3926 O  O   . PRO   D 1 140 ? -14.219 -37.014 -46.685 1.000 37.558  0  250 PRO   C O   1 ? 
ATOM   3927 C  CB  . PRO   D 1 140 ? -13.067 -34.718 -48.520 1.000 38.454  0  250 PRO   C CB  1 ? 
ATOM   3928 C  CG  . PRO   D 1 140 ? -12.910 -33.373 -47.819 1.000 38.400  0  250 PRO   C CG  1 ? 
ATOM   3929 C  CD  . PRO   D 1 140 ? -13.807 -33.447 -46.605 1.000 37.013  0  250 PRO   C CD  1 ? 
ATOM   3930 N  N   . CYS   D 1 141 ? -15.025 -37.484 -48.755 1.000 37.511  0  251 CYS   C N   1 ? 
ATOM   3931 C  CA  . CYS   D 1 141 ? -15.194 -38.913 -48.515 1.000 38.094  0  251 CYS   C CA  1 ? 
ATOM   3932 C  C   . CYS   D 1 141 ? -13.904 -39.677 -48.839 1.000 35.809  0  251 CYS   C C   1 ? 
ATOM   3933 O  O   . CYS   D 1 141 ? -13.816 -40.873 -48.574 1.000 41.298  0  251 CYS   C O   1 ? 
ATOM   3934 C  CB  . CYS   D 1 141 ? -16.370 -39.468 -49.308 1.000 39.098  0  251 CYS   C CB  1 ? 
ATOM   3935 S  SG  . CYS   D 1 141 ? -16.231 -39.196 -51.091 1.000 44.085  0  251 CYS   C SG  1 ? 
ATOM   3936 N  N   . GLU   D 1 142 ? -12.919 -38.978 -49.433 1.000 37.822  0  252 GLU   C N   1 ? 
ATOM   3937 C  CA  . GLU   D 1 142 ? -11.609 -39.559 -49.721 1.000 43.442  0  252 GLU   C CA  1 ? 
ATOM   3938 C  C   . GLU   D 1 142 ? -10.513 -38.651 -49.148 1.000 42.904  0  252 GLU   C C   1 ? 
ATOM   3939 O  O   . GLU   D 1 142 ? -10.656 -37.428 -49.136 1.000 40.006  0  252 GLU   C O   1 ? 
ATOM   3940 C  CB  . GLU   D 1 142 ? -11.424 -39.741 -51.230 1.000 41.897  0  252 GLU   C CB  1 ? 
ATOM   3941 C  CG  . GLU   D 1 142 ? -12.334 -40.803 -51.847 1.000 41.270  0  252 GLU   C CG  1 ? 
ATOM   3942 C  CD  . GLU   D 1 142 ? -12.014 -42.236 -51.446 1.000 45.208  0  252 GLU   C CD  1 ? 
ATOM   3943 O  OE1 . GLU   D 1 142 ? -10.830 -42.629 -51.545 1.000 44.772  0  252 GLU   C OE1 1 ? 
ATOM   3944 O  OE2 . GLU   D 1 142 ? -12.960 -42.981 -51.104 1.000 48.288  0  252 GLU   C OE2 1 ? 
ATOM   3945 N  N   . SER   D 1 143 ? -9.405  -39.268 -48.708 1.000 46.678  0  253 SER   C N   1 ? 
ATOM   3946 C  CA  . SER   D 1 143 ? -8.296  -38.540 -48.092 1.000 51.592  0  253 SER   C CA  1 ? 
ATOM   3947 C  C   . SER   D 1 143 ? -7.035  -38.640 -48.958 1.000 47.293  0  253 SER   C C   1 ? 
ATOM   3948 O  O   . SER   D 1 143 ? -6.286  -37.673 -49.073 1.000 51.732  0  253 SER   C O   1 ? 
ATOM   3949 C  CB  . SER   D 1 143 ? -8.027  -39.043 -46.700 1.000 48.007  0  253 SER   C CB  1 ? 
ATOM   3950 O  OG  . SER   D 1 143 ? -7.513  -40.365 -46.728 1.000 53.363  0  253 SER   C OG  1 ? 
ATOM   3951 N  N   . SER   D 1 144 ? -6.782  -39.839 -49.508 1.000 46.157  0  254 SER   C N   1 ? 
ATOM   3952 C  CA  . SER   D 1 144 ? -5.588  -40.105 -50.304 1.000 50.209  0  254 SER   C CA  1 ? 
ATOM   3953 C  C   . SER   D 1 144 ? -5.252  -38.900 -51.186 1.000 51.379  0  254 SER   C C   1 ? 
ATOM   3954 O  O   . SER   D 1 144 ? -6.088  -38.436 -51.957 1.000 52.823  0  254 SER   C O   1 ? 
ATOM   3955 C  CB  . SER   D 1 144 ? -5.754  -41.348 -51.129 1.000 53.606  0  254 SER   C CB  1 ? 
ATOM   3956 O  OG  . SER   D 1 144 ? -4.608  -41.577 -51.933 1.000 62.831  0  254 SER   C OG  1 ? 
ATOM   3957 N  N   . ALA   D 1 145 ? -3.990  -38.456 -51.108 1.000 51.909  0  255 ALA   C N   1 ? 
ATOM   3958 C  CA  . ALA   D 1 145 ? -3.536  -37.250 -51.785 1.000 55.521  0  255 ALA   C CA  1 ? 
ATOM   3959 C  C   . ALA   D 1 145 ? -3.637  -37.409 -53.303 1.000 48.541  0  255 ALA   C C   1 ? 
ATOM   3960 O  O   . ALA   D 1 145 ? -3.961  -36.454 -54.004 1.000 49.620  0  255 ALA   C O   1 ? 
ATOM   3961 C  CB  . ALA   D 1 145 ? -2.117  -36.929 -51.361 1.000 57.743  0  255 ALA   C CB  1 ? 
ATOM   3962 N  N   . VAL   D 1 146 ? -3.327  -38.615 -53.800 1.000 45.323  0  256 VAL   C N   1 ? 
ATOM   3963 C  CA  . VAL   D 1 146 ? -3.278  -38.870 -55.234 1.000 55.021  0  256 VAL   C CA  1 ? 
ATOM   3964 C  C   . VAL   D 1 146 ? -4.710  -38.938 -55.785 1.000 51.971  0  256 VAL   C C   1 ? 
ATOM   3965 O  O   . VAL   D 1 146 ? -4.976  -38.458 -56.885 1.000 58.278  0  256 VAL   C O   1 ? 
ATOM   3966 C  CB  . VAL   D 1 146 ? -2.477  -40.154 -55.560 1.000 60.231  0  256 VAL   C CB  1 ? 
ATOM   3967 C  CG1 . VAL   D 1 146 ? -3.248  -41.425 -55.210 1.000 62.615  0  256 VAL   C CG1 1 ? 
ATOM   3968 C  CG2 . VAL   D 1 146 ? -2.032  -40.189 -57.016 1.000 60.754  0  256 VAL   C CG2 1 ? 
ATOM   3969 N  N   . VAL   D 1 147 ? -5.627  -39.523 -54.997 1.000 47.237  0  257 VAL   C N   1 ? 
ATOM   3970 C  CA  . VAL   D 1 147 ? -7.022  -39.657 -55.396 1.000 46.961  0  257 VAL   C CA  1 ? 
ATOM   3971 C  C   . VAL   D 1 147 ? -7.652  -38.265 -55.500 1.000 49.077  0  257 VAL   C C   1 ? 
ATOM   3972 O  O   . VAL   D 1 147 ? -8.278  -37.941 -56.504 1.000 48.423  0  257 VAL   C O   1 ? 
ATOM   3973 C  CB  . VAL   D 1 147 ? -7.802  -40.555 -54.413 1.000 52.268  0  257 VAL   C CB  1 ? 
ATOM   3974 C  CG1 . VAL   D 1 147 ? -9.313  -40.456 -54.614 1.000 55.594  0  257 VAL   C CG1 1 ? 
ATOM   3975 C  CG2 . VAL   D 1 147 ? -7.344  -42.008 -54.494 1.000 53.232  0  257 VAL   C CG2 1 ? 
ATOM   3976 N  N   . VAL   D 1 148 ? -7.483  -37.458 -54.446 1.000 46.947  0  258 VAL   C N   1 ? 
ATOM   3977 C  CA  . VAL   D 1 148 ? -8.086  -36.135 -54.380 1.000 47.565  0  258 VAL   C CA  1 ? 
ATOM   3978 C  C   . VAL   D 1 148 ? -7.545  -35.274 -55.524 1.000 48.340  0  258 VAL   C C   1 ? 
ATOM   3979 O  O   . VAL   D 1 148 ? -8.314  -34.609 -56.213 1.000 53.718  0  258 VAL   C O   1 ? 
ATOM   3980 C  CB  . VAL   D 1 148 ? -7.848  -35.472 -53.006 1.000 49.386  0  258 VAL   C CB  1 ? 
ATOM   3981 C  CG1 . VAL   D 1 148 ? -8.201  -33.987 -53.011 1.000 46.730  0  258 VAL   C CG1 1 ? 
ATOM   3982 C  CG2 . VAL   D 1 148 ? -8.604  -36.194 -51.897 1.000 51.433  0  258 VAL   C CG2 1 ? 
ATOM   3983 N  N   . SER   D 1 149 ? -6.222  -35.313 -55.731 1.000 44.224  0  259 SER   C N   1 ? 
ATOM   3984 C  CA  . SER   D 1 149 ? -5.582  -34.502 -56.761 1.000 47.443  0  259 SER   C CA  1 ? 
ATOM   3985 C  C   . SER   D 1 149 ? -6.161  -34.845 -58.138 1.000 43.026  0  259 SER   C C   1 ? 
ATOM   3986 O  O   . SER   D 1 149 ? -6.466  -33.951 -58.925 1.000 50.550  0  259 SER   C O   1 ? 
ATOM   3987 C  CB  . SER   D 1 149 ? -4.076  -34.672 -56.741 1.000 44.528  0  259 SER   C CB  1 ? 
ATOM   3988 O  OG  . SER   D 1 149 ? -3.703  -35.997 -57.097 1.000 58.049  0  259 SER   C OG  1 ? 
ATOM   3989 N  N   . GLY   D 1 150 ? -6.319  -36.147 -58.405 1.000 37.833  0  260 GLY   C N   1 ? 
ATOM   3990 C  CA  . GLY   D 1 150 ? -6.850  -36.624 -59.674 1.000 43.733  0  260 GLY   C CA  1 ? 
ATOM   3991 C  C   . GLY   D 1 150 ? -8.323  -36.241 -59.862 1.000 41.568  0  260 GLY   C C   1 ? 
ATOM   3992 O  O   . GLY   D 1 150 ? -8.710  -35.774 -60.931 1.000 44.803  0  260 GLY   C O   1 ? 
ATOM   3993 N  N   . LEU   D 1 151 ? -9.136  -36.444 -58.814 1.000 38.142  0  261 LEU   C N   1 ? 
ATOM   3994 C  CA  . LEU   D 1 151 ? -10.574 -36.210 -58.901 1.000 42.659  0  261 LEU   C CA  1 ? 
ATOM   3995 C  C   . LEU   D 1 151 ? -10.862 -34.710 -58.993 1.000 40.771  0  261 LEU   C C   1 ? 
ATOM   3996 O  O   . LEU   D 1 151 ? -11.862 -34.311 -59.584 1.000 41.295  0  261 LEU   C O   1 ? 
ATOM   3997 C  CB  . LEU   D 1 151 ? -11.303 -36.852 -57.720 1.000 39.064  0  261 LEU   C CB  1 ? 
ATOM   3998 C  CG  . LEU   D 1 151 ? -11.288 -38.385 -57.668 1.000 43.213  0  261 LEU   C CG  1 ? 
ATOM   3999 C  CD1 . LEU   D 1 151 ? -12.086 -38.886 -56.478 1.000 45.841  0  261 LEU   C CD1 1 ? 
ATOM   4000 C  CD2 . LEU   D 1 151 ? -11.810 -39.005 -58.954 1.000 49.336  0  261 LEU   C CD2 1 ? 
ATOM   4001 N  N   . ARG   D 1 152 ? -9.972  -33.885 -58.418 1.000 44.804  0  262 ARG   C N   1 ? 
ATOM   4002 C  CA  . ARG   D 1 152 ? -10.121 -32.434 -58.473 1.000 48.092  0  262 ARG   C CA  1 ? 
ATOM   4003 C  C   . ARG   D 1 152 ? -10.056 -31.957 -59.928 1.000 43.865  0  262 ARG   C C   1 ? 
ATOM   4004 O  O   . ARG   D 1 152 ? -10.692 -30.969 -60.283 1.000 49.442  0  262 ARG   C O   1 ? 
ATOM   4005 C  CB  . ARG   D 1 152 ? -9.061  -31.717 -57.623 1.000 51.383  0  262 ARG   C CB  1 ? 
ATOM   4006 C  CG  . ARG   D 1 152 ? -9.347  -31.705 -56.128 1.000 59.246  0  262 ARG   C CG  1 ? 
ATOM   4007 C  CD  . ARG   D 1 152 ? -8.374  -30.812 -55.366 1.000 69.632  0  262 ARG   C CD  1 ? 
ATOM   4008 N  NE  . ARG   D 1 152 ? -8.593  -30.856 -53.914 1.000 76.627  0  262 ARG   C NE  1 ? 
ATOM   4009 C  CZ  . ARG   D 1 152 ? -7.910  -30.148 -53.009 1.000 77.749  0  262 ARG   C CZ  1 ? 
ATOM   4010 N  NH1 . ARG   D 1 152 ? -6.982  -29.282 -53.394 1.000 78.840  0  262 ARG   C NH1 1 ? 
ATOM   4011 N  NH2 . ARG   D 1 152 ? -8.178  -30.293 -51.721 1.000 83.305  0  262 ARG   C NH2 1 ? 
ATOM   4012 N  N   . THR   D 1 153 ? -9.282  -32.674 -60.759 1.000 37.307  0  263 THR   C N   1 ? 
ATOM   4013 C  CA  . THR   D 1 153 ? -9.108  -32.325 -62.167 1.000 40.123  0  263 THR   C CA  1 ? 
ATOM   4014 C  C   . THR   D 1 153 ? -10.417 -32.549 -62.943 1.000 37.388  0  263 THR   C C   1 ? 
ATOM   4015 O  O   . THR   D 1 153 ? -10.621 -31.949 -63.996 1.000 34.751  0  263 THR   C O   1 ? 
ATOM   4016 C  CB  . THR   D 1 153 ? -7.959  -33.155 -62.749 1.000 46.729  0  263 THR   C CB  1 ? 
ATOM   4017 O  OG1 . THR   D 1 153 ? -6.777  -32.646 -62.142 1.000 53.785  0  263 THR   C OG1 1 ? 
ATOM   4018 C  CG2 . THR   D 1 153 ? -7.837  -33.029 -64.256 1.000 63.893  0  263 THR   C CG2 1 ? 
ATOM   4019 N  N   . LEU   D 1 154 ? -11.288 -33.428 -62.419 1.000 34.176  0  264 LEU   C N   1 ? 
ATOM   4020 C  CA  . LEU   D 1 154 ? -12.501 -33.834 -63.119 1.000 34.937  0  264 LEU   C CA  1 ? 
ATOM   4021 C  C   . LEU   D 1 154 ? -13.683 -32.943 -62.733 1.000 33.820  0  264 LEU   C C   1 ? 
ATOM   4022 O  O   . LEU   D 1 154 ? -14.660 -32.876 -63.472 1.000 31.589  0  264 LEU   C O   1 ? 
ATOM   4023 C  CB  . LEU   D 1 154 ? -12.803 -35.299 -62.803 1.000 36.510  0  264 LEU   C CB  1 ? 
ATOM   4024 C  CG  . LEU   D 1 154 ? -11.746 -36.318 -63.229 1.000 34.460  0  264 LEU   C CG  1 ? 
ATOM   4025 C  CD1 . LEU   D 1 154 ? -12.168 -37.704 -62.796 1.000 35.468  0  264 LEU   C CD1 1 ? 
ATOM   4026 C  CD2 . LEU   D 1 154 ? -11.496 -36.280 -64.730 1.000 39.112  0  264 LEU   C CD2 1 ? 
ATOM   4027 N  N   . VAL   D 1 155 ? -13.608 -32.301 -61.550 1.000 38.389  0  265 VAL   C N   1 ? 
ATOM   4028 C  CA  . VAL   D 1 155 ? -14.752 -31.585 -60.986 1.000 39.817  0  265 VAL   C CA  1 ? 
ATOM   4029 C  C   . VAL   D 1 155 ? -15.179 -30.478 -61.953 1.000 38.845  0  265 VAL   C C   1 ? 
ATOM   4030 O  O   . VAL   D 1 155 ? -14.356 -29.672 -62.376 1.000 43.887  0  265 VAL   C O   1 ? 
ATOM   4031 C  CB  . VAL   D 1 155 ? -14.461 -31.003 -59.585 1.000 38.591  0  265 VAL   C CB  1 ? 
ATOM   4032 C  CG1 . VAL   D 1 155 ? -15.643 -30.201 -59.046 1.000 41.452  0  265 VAL   C CG1 1 ? 
ATOM   4033 C  CG2 . VAL   D 1 155 ? -14.061 -32.085 -58.589 1.000 38.626  0  265 VAL   C CG2 1 ? 
ATOM   4034 N  N   . PRO   D 1 156 ? -16.479 -30.409 -62.335 1.000 46.528  0  266 PRO   C N   1 ? 
ATOM   4035 C  CA  . PRO   D 1 156 ? -16.983 -29.302 -63.147 1.000 51.640  0  266 PRO   C CA  1 ? 
ATOM   4036 C  C   . PRO   D 1 156 ? -17.244 -28.060 -62.300 1.000 49.469  0  266 PRO   C C   1 ? 
ATOM   4037 O  O   . PRO   D 1 156 ? -16.723 -26.994 -62.676 1.000 62.674  0  266 PRO   C O   1 ? 
ATOM   4038 C  CB  . PRO   D 1 156 ? -18.273 -29.885 -63.759 1.000 46.071  0  266 PRO   C CB  1 ? 
ATOM   4039 C  CG  . PRO   D 1 156 ? -18.771 -30.861 -62.700 1.000 46.841  0  266 PRO   C CG  1 ? 
ATOM   4040 C  CD  . PRO   D 1 156 ? -17.510 -31.420 -62.049 1.000 50.816  0  266 PRO   C CD  1 ? 
HETATM 4041 C  C4  . A1ECX E 2 .   ? -39.814 -21.040 7.055   1.000 76.063  0  301 A1ECX D C4  1 ? 
HETATM 4042 C  C5  . A1ECX E 2 .   ? -41.038 -20.681 6.530   1.000 63.152  0  301 A1ECX D C5  1 ? 
HETATM 4043 C  C6  . A1ECX E 2 .   ? -41.516 -19.404 6.700   1.000 73.521  0  301 A1ECX D C6  1 ? 
HETATM 4044 C  C7  . A1ECX E 2 .   ? -40.756 -18.455 7.388   1.000 82.795  0  301 A1ECX D C7  1 ? 
HETATM 4045 C  C8  . A1ECX E 2 .   ? -37.675 -20.606 8.290   1.000 90.115  0  301 A1ECX D C8  1 ? 
HETATM 4046 C  C10 . A1ECX E 2 .   ? -38.517 -21.452 10.556  1.000 68.366  0  301 A1ECX D C10 1 ? 
HETATM 4047 C  C13 . A1ECX E 2 .   ? -37.710 -19.592 13.528  1.000 46.145  0  301 A1ECX D C13 1 ? 
HETATM 4048 C  C15 . A1ECX E 2 .   ? -40.045 -19.711 14.575  1.000 53.424  0  301 A1ECX D C15 1 ? 
HETATM 4049 C  C17 . A1ECX E 2 .   ? -40.369 -21.942 15.682  1.000 50.628  0  301 A1ECX D C17 1 ? 
HETATM 4050 C  C20 . A1ECX E 2 .   ? -39.141 -21.333 18.725  1.000 51.048  0  301 A1ECX D C20 1 ? 
HETATM 4051 C  C21 . A1ECX E 2 .   ? -39.299 -19.811 18.725  1.000 58.338  0  301 A1ECX D C21 1 ? 
HETATM 4052 C  C22 . A1ECX E 2 .   ? -40.443 -19.296 19.586  1.000 67.874  0  301 A1ECX D C22 1 ? 
HETATM 4053 C  C24 . A1ECX E 2 .   ? -39.718 -16.904 20.021  1.000 51.002  0  301 A1ECX D C24 1 ? 
HETATM 4054 O  O1  . A1ECX E 2 .   ? -39.099 -16.557 8.654   1.000 54.353  0  301 A1ECX D O1  1 ? 
HETATM 4055 C  C1  . A1ECX E 2 .   ? -38.692 -17.739 8.687   1.000 62.998  0  301 A1ECX D C1  1 ? 
HETATM 4056 C  C2  . A1ECX E 2 .   ? -39.499 -18.795 7.924   1.000 75.818  0  301 A1ECX D C2  1 ? 
HETATM 4057 C  C3  . A1ECX E 2 .   ? -39.026 -20.130 7.767   1.000 85.745  0  301 A1ECX D C3  1 ? 
HETATM 4058 O  O2  . A1ECX E 2 .   ? -41.267 -17.196 7.522   1.000 90.128  0  301 A1ECX D O2  1 ? 
HETATM 4059 C  C9  . A1ECX E 2 .   ? -37.765 -21.772 9.266   1.000 78.594  0  301 A1ECX D C9  1 ? 
HETATM 4060 C  C11 . A1ECX E 2 .   ? -37.662 -21.476 11.807  1.000 55.952  0  301 A1ECX D C11 1 ? 
HETATM 4061 C  C12 . A1ECX E 2 .   ? -37.124 -20.117 12.232  1.000 56.089  0  301 A1ECX D C12 1 ? 
HETATM 4062 C  C14 . A1ECX E 2 .   ? -39.172 -19.195 13.433  1.000 52.512  0  301 A1ECX D C14 1 ? 
HETATM 4063 C  C16 . A1ECX E 2 .   ? -40.503 -21.145 14.423  1.000 51.069  0  301 A1ECX D C16 1 ? 
HETATM 4064 C  C18 . A1ECX E 2 .   ? -40.797 -21.567 16.849  1.000 51.112  0  301 A1ECX D C18 1 ? 
HETATM 4065 C  C19 . A1ECX E 2 .   ? -40.326 -22.092 18.165  1.000 55.107  0  301 A1ECX D C19 1 ? 
HETATM 4066 C  C23 . A1ECX E 2 .   ? -40.751 -17.826 19.405  1.000 64.294  0  301 A1ECX D C23 1 ? 
HETATM 4067 O  O3  . A1ECX E 2 .   ? -37.714 -18.113 9.335   1.000 61.816  -1 301 A1ECX D O3  1 ? 
HETATM 4068 C  C4  . A1ECX F 2 .   ? -41.602 -18.160 -0.353  1.000 70.414  0  302 A1ECX D C4  1 ? 
HETATM 4069 C  C5  . A1ECX F 2 .   ? -40.619 -19.109 -0.145  1.000 76.969  0  302 A1ECX D C5  1 ? 
HETATM 4070 C  C6  . A1ECX F 2 .   ? -40.930 -20.312 0.443   1.000 59.681  0  302 A1ECX D C6  1 ? 
HETATM 4071 C  C7  . A1ECX F 2 .   ? -42.238 -20.581 0.834   1.000 65.413  0  302 A1ECX D C7  1 ? 
HETATM 4072 C  C8  . A1ECX F 2 .   ? -43.946 -17.298 -0.272  1.000 59.334  0  302 A1ECX D C8  1 ? 
HETATM 4073 C  C10 . A1ECX F 2 .   ? -46.062 -17.626 -1.701  1.000 63.833  0  302 A1ECX D C10 1 ? 
HETATM 4074 C  C13 . A1ECX F 2 .   ? -47.136 -14.402 -2.163  1.000 53.124  0  302 A1ECX D C13 1 ? 
HETATM 4075 C  C15 . A1ECX F 2 .   ? -47.318 -14.137 -4.705  1.000 63.976  0  302 A1ECX D C15 1 ? 
HETATM 4076 C  C17 . A1ECX F 2 .   ? -49.752 -13.934 -4.056  1.000 64.021  0  302 A1ECX D C17 1 ? 
HETATM 4077 C  C20 . A1ECX F 2 .   ? -50.734 -10.928 -4.106  1.000 91.921  0  302 A1ECX D C20 1 ? 
HETATM 4078 C  C21 . A1ECX F 2 .   ? -50.639 -10.893 -2.582  1.000 89.160  0  302 A1ECX D C21 1 ? 
HETATM 4079 C  C22 . A1ECX F 2 .   ? -49.609 -9.917  -2.044  1.000 84.238  0  302 A1ECX D C22 1 ? 
HETATM 4080 C  C24 . A1ECX F 2 .   ? -49.348 -7.761  -0.750  1.000 78.475  0  302 A1ECX D C24 1 ? 
HETATM 4081 O  O1  . A1ECX F 2 .   ? -45.442 -18.990 1.287   1.000 109.474 0  302 A1ECX D O1  1 ? 
HETATM 4082 C  C1  . A1ECX F 2 .   ? -44.681 -19.939 1.076   1.000 97.629  0  302 A1ECX D C1  1 ? 
HETATM 4083 C  C2  . A1ECX F 2 .   ? -43.261 -19.633 0.618   1.000 70.369  0  302 A1ECX D C2  1 ? 
HETATM 4084 C  C3  . A1ECX F 2 .   ? -42.921 -18.377 0.039   1.000 59.368  0  302 A1ECX D C3  1 ? 
HETATM 4085 O  O2  . A1ECX F 2 .   ? -42.489 -21.776 1.438   1.000 87.514  0  302 A1ECX D O2  1 ? 
HETATM 4086 C  C9  . A1ECX F 2 .   ? -44.551 -17.408 -1.672  1.000 51.464  0  302 A1ECX D C9  1 ? 
HETATM 4087 C  C11 . A1ECX F 2 .   ? -46.888 -16.610 -0.902  1.000 65.102  0  302 A1ECX D C11 1 ? 
HETATM 4088 C  C12 . A1ECX F 2 .   ? -46.446 -15.155 -1.051  1.000 67.775  0  302 A1ECX D C12 1 ? 
HETATM 4089 C  C14 . A1ECX F 2 .   ? -47.026 -15.061 -3.523  1.000 63.460  0  302 A1ECX D C14 1 ? 
HETATM 4090 C  C16 . A1ECX F 2 .   ? -48.512 -13.226 -4.520  1.000 64.393  0  302 A1ECX D C16 1 ? 
HETATM 4091 C  C18 . A1ECX F 2 .   ? -50.977 -13.451 -4.068  1.000 80.807  0  302 A1ECX D C18 1 ? 
HETATM 4092 C  C19 . A1ECX F 2 .   ? -51.425 -12.150 -4.674  1.000 81.557  0  302 A1ECX D C19 1 ? 
HETATM 4093 C  C23 . A1ECX F 2 .   ? -50.124 -8.518  -1.804  1.000 84.636  0  302 A1ECX D C23 1 ? 
HETATM 4094 O  O3  . A1ECX F 2 .   ? -45.013 -21.137 1.177   1.000 120.566 -1 302 A1ECX D O3  1 ? 
HETATM 4095 CL CL  . CL    G 3 .   ? -41.855 -19.547 3.563   1.000 64.653  0  303 CL    D CL  1 ? 
HETATM 4096 CL CL  . CL    H 3 .   ? -41.148 -16.809 12.208  1.000 80.255  0  304 CL    D CL  1 ? 
HETATM 4097 CL CL  . CL    I 3 .   ? -11.609 -29.413 -37.000 1.000 83.254  0  301 CL    A CL  1 ? 
HETATM 4098 O  O   . HOH   J 4 .   ? -14.323 -14.193 -4.309  1.000 43.600  0  401 HOH   D O   1 ? 
HETATM 4099 O  O   . HOH   J 4 .   ? -22.813 -10.648 5.591   1.000 45.550  0  402 HOH   D O   1 ? 
HETATM 4100 O  O   . HOH   J 4 .   ? -20.709 -12.282 7.321   1.000 42.617  0  403 HOH   D O   1 ? 
HETATM 4101 O  O   . HOH   J 4 .   ? -25.991 -16.825 7.621   1.000 54.018  0  404 HOH   D O   1 ? 
HETATM 4102 O  O   . HOH   J 4 .   ? -40.228 -17.116 -9.833  1.000 39.314  0  405 HOH   D O   1 ? 
HETATM 4103 O  O   . HOH   J 4 .   ? -42.612 -12.632 9.135   1.000 38.635  0  406 HOH   D O   1 ? 
HETATM 4104 O  O   . HOH   J 4 .   ? -29.791 -19.676 8.226   1.000 52.626  0  407 HOH   D O   1 ? 
HETATM 4105 O  O   . HOH   J 4 .   ? -24.081 -25.622 -16.791 1.000 29.808  0  408 HOH   D O   1 ? 
HETATM 4106 O  O   . HOH   J 4 .   ? -15.285 -16.060 -6.206  1.000 42.531  0  409 HOH   D O   1 ? 
HETATM 4107 O  O   . HOH   J 4 .   ? -34.531 -3.590  -4.961  1.000 45.633  0  410 HOH   D O   1 ? 
HETATM 4108 O  O   . HOH   J 4 .   ? -44.505 -22.554 -1.052  1.000 57.513  0  411 HOH   D O   1 ? 
HETATM 4109 O  O   . HOH   J 4 .   ? -1.778  -19.485 -13.655 1.000 58.566  0  412 HOH   D O   1 ? 
HETATM 4110 O  O   . HOH   J 4 .   ? -23.845 -19.812 10.128  1.000 46.472  0  413 HOH   D O   1 ? 
HETATM 4111 O  O   . HOH   J 4 .   ? -17.474 -7.818  -15.138 1.000 40.045  0  414 HOH   D O   1 ? 
HETATM 4112 O  O   . HOH   J 4 .   ? -6.165  -24.150 -18.040 1.000 50.805  0  415 HOH   D O   1 ? 
HETATM 4113 O  O   . HOH   J 4 .   ? -9.754  -26.363 -25.299 1.000 50.934  0  416 HOH   D O   1 ? 
HETATM 4114 O  O   . HOH   J 4 .   ? -19.356 -18.279 -8.209  1.000 51.673  0  417 HOH   D O   1 ? 
HETATM 4115 O  O   . HOH   J 4 .   ? -30.997 -19.503 5.923   1.000 45.889  0  418 HOH   D O   1 ? 
HETATM 4116 O  O   . HOH   J 4 .   ? -19.017 -27.310 -11.972 1.000 40.749  0  419 HOH   D O   1 ? 
HETATM 4117 O  O   . HOH   J 4 .   ? -33.193 -17.905 6.908   1.000 44.744  0  420 HOH   D O   1 ? 
HETATM 4118 O  O   . HOH   J 4 .   ? -36.787 -9.610  -10.884 1.000 41.013  0  421 HOH   D O   1 ? 
HETATM 4119 O  O   . HOH   J 4 .   ? -33.881 -0.563  -1.117  1.000 43.964  0  422 HOH   D O   1 ? 
HETATM 4120 O  O   . HOH   J 4 .   ? -23.101 -29.867 -9.549  1.000 56.632  0  423 HOH   D O   1 ? 
HETATM 4121 O  O   . HOH   J 4 .   ? -11.337 -12.631 -4.888  1.000 49.589  0  424 HOH   D O   1 ? 
HETATM 4122 O  O   . HOH   J 4 .   ? -25.299 -31.061 -15.166 1.000 50.075  0  425 HOH   D O   1 ? 
HETATM 4123 O  O   . HOH   J 4 .   ? -20.467 -27.874 -9.564  1.000 39.523  0  426 HOH   D O   1 ? 
HETATM 4124 O  O   . HOH   J 4 .   ? -41.537 -25.887 0.140   1.000 43.755  0  427 HOH   D O   1 ? 
HETATM 4125 O  O   . HOH   J 4 .   ? -29.261 -12.636 -15.353 1.000 40.041  0  428 HOH   D O   1 ? 
HETATM 4126 O  O   . HOH   J 4 .   ? -42.666 -18.015 -8.545  1.000 40.038  0  429 HOH   D O   1 ? 
HETATM 4127 O  O   . HOH   J 4 .   ? -26.523 -30.792 2.810   1.000 43.934  0  430 HOH   D O   1 ? 
HETATM 4128 O  O   . HOH   J 4 .   ? -40.485 -4.527  -2.205  1.000 39.068  0  431 HOH   D O   1 ? 
HETATM 4129 O  O   . HOH   J 4 .   ? -45.881 -11.910 1.331   1.000 51.536  0  432 HOH   D O   1 ? 
HETATM 4130 O  O   . HOH   J 4 .   ? -39.432 -2.754  -0.537  1.000 49.515  0  433 HOH   D O   1 ? 
HETATM 4131 O  O   . HOH   J 4 .   ? -23.663 -32.764 -17.778 1.000 56.091  0  434 HOH   D O   1 ? 
HETATM 4132 O  O   . HOH   J 4 .   ? -20.707 -14.858 8.112   1.000 51.505  0  435 HOH   D O   1 ? 
HETATM 4133 O  O   . HOH   K 4 .   ? -31.878 -5.761  -15.331 1.000 51.150  0  401 HOH   A O   1 ? 
HETATM 4134 O  O   . HOH   K 4 .   ? -12.061 -6.163  -15.998 1.000 51.309  0  402 HOH   A O   1 ? 
HETATM 4135 O  O   . HOH   K 4 .   ? -15.701 -2.276  -25.183 1.000 66.190  0  403 HOH   A O   1 ? 
HETATM 4136 O  O   . HOH   K 4 .   ? -13.589 -18.040 -7.479  1.000 39.820  0  404 HOH   A O   1 ? 
HETATM 4137 O  O   . HOH   K 4 .   ? -24.847 -22.272 -25.832 1.000 32.642  0  405 HOH   A O   1 ? 
HETATM 4138 O  O   . HOH   K 4 .   ? -30.431 -3.022  -23.696 1.000 36.468  0  406 HOH   A O   1 ? 
HETATM 4139 O  O   . HOH   K 4 .   ? -30.483 -20.431 -22.281 1.000 53.658  0  407 HOH   A O   1 ? 
HETATM 4140 O  O   . HOH   K 4 .   ? -13.033 -27.327 -26.898 1.000 36.165  0  408 HOH   A O   1 ? 
HETATM 4141 O  O   . HOH   K 4 .   ? -20.186 1.155   -36.337 1.000 36.536  0  409 HOH   A O   1 ? 
HETATM 4142 O  O   . HOH   K 4 .   ? -30.767 -11.449 -13.614 1.000 40.801  0  410 HOH   A O   1 ? 
HETATM 4143 O  O   . HOH   K 4 .   ? -33.499 -15.547 -23.360 1.000 39.842  0  411 HOH   A O   1 ? 
HETATM 4144 O  O   . HOH   K 4 .   ? -14.963 -13.818 -42.689 1.000 59.706  0  412 HOH   A O   1 ? 
HETATM 4145 O  O   . HOH   K 4 .   ? -32.159 -6.728  -25.008 1.000 45.472  0  413 HOH   A O   1 ? 
HETATM 4146 O  O   . HOH   K 4 .   ? -3.628  -12.039 -18.840 1.000 60.110  0  414 HOH   A O   1 ? 
HETATM 4147 O  O   . HOH   K 4 .   ? -19.713 -0.500  -41.775 1.000 42.364  0  415 HOH   A O   1 ? 
HETATM 4148 O  O   . HOH   K 4 .   ? -33.112 -12.024 -18.418 1.000 49.038  0  416 HOH   A O   1 ? 
HETATM 4149 O  O   . HOH   K 4 .   ? -11.721 -20.972 -9.126  1.000 50.617  0  417 HOH   A O   1 ? 
HETATM 4150 O  O   . HOH   K 4 .   ? -29.350 -0.533  -20.625 1.000 42.550  0  418 HOH   A O   1 ? 
HETATM 4151 O  O   . HOH   K 4 .   ? -26.303 -24.207 -24.398 1.000 50.085  0  419 HOH   A O   1 ? 
HETATM 4152 O  O   . HOH   K 4 .   ? -26.933 -0.697  -15.948 1.000 42.069  0  420 HOH   A O   1 ? 
HETATM 4153 O  O   . HOH   K 4 .   ? -10.141 -6.319  -13.402 1.000 55.519  0  421 HOH   A O   1 ? 
HETATM 4154 O  O   . HOH   K 4 .   ? -18.460 -0.081  -28.611 1.000 35.704  0  422 HOH   A O   1 ? 
HETATM 4155 O  O   . HOH   K 4 .   ? -17.256 -16.009 -8.138  1.000 33.646  0  423 HOH   A O   1 ? 
HETATM 4156 O  O   . HOH   K 4 .   ? -21.629 -2.770  -41.865 1.000 59.135  0  424 HOH   A O   1 ? 
HETATM 4157 O  O   . HOH   K 4 .   ? -17.501 -23.968 -42.051 1.000 57.276  0  425 HOH   A O   1 ? 
HETATM 4158 O  O   . HOH   K 4 .   ? -31.395 -20.737 -29.396 1.000 51.415  0  426 HOH   A O   1 ? 
HETATM 4159 O  O   . HOH   K 4 .   ? -34.261 -16.230 -28.532 1.000 48.257  0  427 HOH   A O   1 ? 
HETATM 4160 O  O   . HOH   K 4 .   ? -12.621 -4.627  -21.387 1.000 60.683  0  428 HOH   A O   1 ? 
HETATM 4161 O  O   . HOH   K 4 .   ? -6.797  -12.763 -15.712 1.000 55.758  0  429 HOH   A O   1 ? 
HETATM 4162 O  O   . HOH   K 4 .   ? -16.525 -26.136 -11.947 1.000 38.030  0  430 HOH   A O   1 ? 
HETATM 4163 O  O   . HOH   K 4 .   ? -34.705 -12.107 -35.777 1.000 57.913  0  431 HOH   A O   1 ? 
HETATM 4164 O  O   . HOH   K 4 .   ? -31.601 -23.745 -28.961 1.000 45.352  0  432 HOH   A O   1 ? 
HETATM 4165 O  O   . HOH   K 4 .   ? -34.376 -14.901 -31.054 1.000 54.785  0  433 HOH   A O   1 ? 
HETATM 4166 O  O   . HOH   K 4 .   ? -21.735 1.354   -41.712 1.000 43.880  0  434 HOH   A O   1 ? 
HETATM 4167 O  O   . HOH   K 4 .   ? -10.580 -5.594  -18.148 1.000 58.370  0  435 HOH   A O   1 ? 
HETATM 4168 O  O   . HOH   K 4 .   ? -30.532 2.303   -16.285 1.000 58.850  0  436 HOH   A O   1 ? 
HETATM 4169 O  O   . HOH   K 4 .   ? -11.428 -28.504 -25.193 1.000 40.912  0  437 HOH   A O   1 ? 
HETATM 4170 O  O   . HOH   K 4 .   ? -29.772 1.820   -18.779 1.000 59.002  0  438 HOH   A O   1 ? 
HETATM 4171 O  O   . HOH   K 4 .   ? -9.547  -30.649 -38.600 1.000 56.019  0  439 HOH   A O   1 ? 
HETATM 4172 O  O   . HOH   L 4 .   ? -19.411 -27.683 34.228  1.000 38.738  0  301 HOH   B O   1 ? 
HETATM 4173 O  O   . HOH   L 4 .   ? -14.789 -7.084  28.240  1.000 40.092  0  302 HOH   B O   1 ? 
HETATM 4174 O  O   . HOH   L 4 .   ? -13.522 -24.106 6.665   1.000 47.018  0  303 HOH   B O   1 ? 
HETATM 4175 O  O   . HOH   L 4 .   ? -11.076 -5.680  26.132  1.000 46.025  0  304 HOH   B O   1 ? 
HETATM 4176 O  O   . HOH   L 4 .   ? -20.547 -34.198 6.393   1.000 47.621  0  305 HOH   B O   1 ? 
HETATM 4177 O  O   . HOH   L 4 .   ? -2.480  -32.054 24.057  1.000 46.378  0  306 HOH   B O   1 ? 
HETATM 4178 O  O   . HOH   L 4 .   ? -15.007 -6.683  25.258  1.000 43.456  0  307 HOH   B O   1 ? 
HETATM 4179 O  O   . HOH   L 4 .   ? -2.942  -28.326 0.088   1.000 64.900  0  308 HOH   B O   1 ? 
HETATM 4180 O  O   . HOH   L 4 .   ? 5.659   -28.562 20.142  1.000 42.872  0  309 HOH   B O   1 ? 
HETATM 4181 O  O   . HOH   L 4 .   ? -21.217 -29.437 31.321  1.000 49.907  0  310 HOH   B O   1 ? 
HETATM 4182 O  O   . HOH   L 4 .   ? -16.790 -34.901 24.236  1.000 50.971  0  311 HOH   B O   1 ? 
HETATM 4183 O  O   . HOH   L 4 .   ? -9.163  -21.632 29.951  1.000 61.197  0  312 HOH   B O   1 ? 
HETATM 4184 O  O   . HOH   L 4 .   ? -1.958  -30.642 5.638   1.000 55.032  0  313 HOH   B O   1 ? 
HETATM 4185 O  O   . HOH   L 4 .   ? 1.523   -14.275 16.245  1.000 45.743  0  314 HOH   B O   1 ? 
HETATM 4186 O  O   . HOH   L 4 .   ? -11.673 -10.662 4.967   1.000 46.900  0  315 HOH   B O   1 ? 
HETATM 4187 O  O   . HOH   L 4 .   ? -20.265 -20.915 22.880  1.000 52.963  0  316 HOH   B O   1 ? 
HETATM 4188 O  O   . HOH   L 4 .   ? -19.060 -15.638 10.137  1.000 47.853  0  317 HOH   B O   1 ? 
HETATM 4189 O  O   . HOH   L 4 .   ? -26.215 -27.573 26.556  1.000 44.734  0  318 HOH   B O   1 ? 
HETATM 4190 O  O   . HOH   L 4 .   ? -34.565 -24.825 33.623  1.000 50.322  0  319 HOH   B O   1 ? 
HETATM 4191 O  O   . HOH   L 4 .   ? 0.038   -31.046 24.187  1.000 52.971  0  320 HOH   B O   1 ? 
HETATM 4192 O  O   . HOH   L 4 .   ? -15.949 -6.231  14.135  1.000 54.296  0  321 HOH   B O   1 ? 
HETATM 4193 O  O   . HOH   L 4 .   ? -22.812 -33.367 24.057  1.000 56.282  0  322 HOH   B O   1 ? 
HETATM 4194 O  O   . HOH   L 4 .   ? -22.526 -32.621 5.255   1.000 47.764  0  323 HOH   B O   1 ? 
HETATM 4195 O  O   . HOH   L 4 .   ? -8.681  -33.684 5.876   1.000 49.593  0  324 HOH   B O   1 ? 
HETATM 4196 O  O   . HOH   L 4 .   ? 5.664   -27.417 7.013   1.000 45.390  0  325 HOH   B O   1 ? 
HETATM 4197 O  O   . HOH   L 4 .   ? -1.247  -13.598 2.888   1.000 54.198  0  326 HOH   B O   1 ? 
HETATM 4198 O  O   . HOH   L 4 .   ? -5.231  -9.302  28.755  1.000 38.481  0  327 HOH   B O   1 ? 
HETATM 4199 O  O   . HOH   L 4 .   ? -2.724  -9.206  7.613   1.000 48.521  0  328 HOH   B O   1 ? 
HETATM 4200 O  O   . HOH   L 4 .   ? -15.953 -10.938 30.003  1.000 42.758  0  329 HOH   B O   1 ? 
HETATM 4201 O  O   . HOH   L 4 .   ? -4.829  -28.565 1.917   1.000 58.274  0  330 HOH   B O   1 ? 
HETATM 4202 O  O   . HOH   L 4 .   ? -2.209  -34.876 11.750  1.000 53.752  0  331 HOH   B O   1 ? 
HETATM 4203 O  O   . HOH   L 4 .   ? -0.686  -34.584 14.056  1.000 60.275  0  332 HOH   B O   1 ? 
HETATM 4204 O  O   . HOH   L 4 .   ? -28.717 -26.720 24.163  1.000 61.539  0  333 HOH   B O   1 ? 
HETATM 4205 O  O   . HOH   L 4 .   ? -23.379 -36.753 21.694  1.000 48.450  0  334 HOH   B O   1 ? 
HETATM 4206 O  O   . HOH   L 4 .   ? -15.461 -5.374  18.701  1.000 49.004  0  335 HOH   B O   1 ? 
HETATM 4207 O  O   . HOH   L 4 .   ? -25.995 -36.995 20.753  1.000 56.299  0  336 HOH   B O   1 ? 
HETATM 4208 O  O   . HOH   M 4 .   ? -8.786  -38.717 -41.324 1.000 47.419  0  301 HOH   C O   1 ? 
HETATM 4209 O  O   . HOH   M 4 .   ? -15.724 -30.095 -23.509 1.000 35.163  0  302 HOH   C O   1 ? 
HETATM 4210 O  O   . HOH   M 4 .   ? -17.875 -53.290 -36.191 1.000 41.829  0  303 HOH   C O   1 ? 
HETATM 4211 O  O   . HOH   M 4 .   ? -36.691 -48.042 -37.935 1.000 37.223  0  304 HOH   C O   1 ? 
HETATM 4212 O  O   . HOH   M 4 .   ? -17.812 -24.635 -62.751 1.000 53.076  0  305 HOH   C O   1 ? 
HETATM 4213 O  O   . HOH   M 4 .   ? -39.707 -34.114 -42.638 1.000 57.986  0  306 HOH   C O   1 ? 
HETATM 4214 O  O   . HOH   M 4 .   ? -25.673 -43.423 -23.141 1.000 53.442  0  307 HOH   C O   1 ? 
HETATM 4215 O  O   . HOH   M 4 .   ? -23.620 -55.841 -43.258 1.000 59.307  0  308 HOH   C O   1 ? 
HETATM 4216 O  O   . HOH   M 4 .   ? -8.897  -42.212 -49.779 1.000 48.518  0  309 HOH   C O   1 ? 
HETATM 4217 O  O   . HOH   M 4 .   ? -9.154  -44.690 -51.604 1.000 55.436  0  310 HOH   C O   1 ? 
HETATM 4218 O  O   . HOH   M 4 .   ? -17.254 -50.225 -44.793 1.000 45.401  0  311 HOH   C O   1 ? 
HETATM 4219 O  O   . HOH   M 4 .   ? -9.921  -34.862 -48.938 1.000 42.786  0  312 HOH   C O   1 ? 
HETATM 4220 O  O   . HOH   M 4 .   ? -12.508 -49.621 -32.909 1.000 64.070  0  313 HOH   C O   1 ? 
HETATM 4221 O  O   . HOH   M 4 .   ? -39.782 -47.851 -28.776 1.000 53.161  0  314 HOH   C O   1 ? 
HETATM 4222 O  O   . HOH   M 4 .   ? -9.588  -33.730 -23.322 1.000 58.852  0  315 HOH   C O   1 ? 
HETATM 4223 O  O   . HOH   M 4 .   ? -23.673 -38.271 -28.251 1.000 43.886  0  316 HOH   C O   1 ? 
HETATM 4224 O  O   . HOH   M 4 .   ? -26.347 -41.462 -56.821 1.000 50.967  0  317 HOH   C O   1 ? 
HETATM 4225 O  O   . HOH   M 4 .   ? -14.034 -28.948 -29.001 1.000 28.496  0  318 HOH   C O   1 ? 
HETATM 4226 O  O   . HOH   M 4 .   ? -16.247 -29.185 -36.601 1.000 43.161  0  319 HOH   C O   1 ? 
HETATM 4227 O  O   . HOH   M 4 .   ? -41.678 -45.370 -33.061 1.000 49.798  0  320 HOH   C O   1 ? 
HETATM 4228 O  O   . HOH   M 4 .   ? -24.240 -53.585 -41.150 1.000 41.306  0  321 HOH   C O   1 ? 
HETATM 4229 O  O   . HOH   M 4 .   ? -30.555 -40.899 -58.056 1.000 37.896  0  322 HOH   C O   1 ? 
HETATM 4230 O  O   . HOH   M 4 .   ? -34.256 -42.366 -56.186 1.000 53.013  0  323 HOH   C O   1 ? 
HETATM 4231 O  O   . HOH   M 4 .   ? -10.259 -34.491 -46.172 1.000 42.206  0  324 HOH   C O   1 ? 
HETATM 4232 O  O   . HOH   M 4 .   ? -28.127 -52.236 -40.460 1.000 57.596  0  325 HOH   C O   1 ? 
HETATM 4233 O  O   . HOH   M 4 .   ? -9.124  -39.829 -26.404 1.000 49.495  0  326 HOH   C O   1 ? 
HETATM 4234 O  O   . HOH   M 4 .   ? -8.657  -42.467 -40.130 1.000 45.463  0  327 HOH   C O   1 ? 
HETATM 4235 O  O   . HOH   M 4 .   ? -22.718 -34.496 -28.913 1.000 49.484  0  328 HOH   C O   1 ? 
HETATM 4236 O  O   . HOH   M 4 .   ? -22.057 -36.815 -29.671 1.000 36.258  0  329 HOH   C O   1 ? 
HETATM 4237 O  O   . HOH   M 4 .   ? -33.279 -49.295 -53.389 1.000 34.798  0  330 HOH   C O   1 ? 
HETATM 4238 O  O   . HOH   M 4 .   ? -19.574 -55.358 -35.859 1.000 49.602  0  331 HOH   C O   1 ? 
HETATM 4239 O  O   . HOH   M 4 .   ? -12.803 -30.995 -66.105 1.000 37.724  0  332 HOH   C O   1 ? 
HETATM 4240 O  O   . HOH   M 4 .   ? -5.510  -31.223 -57.586 1.000 52.127  0  333 HOH   C O   1 ? 
HETATM 4241 O  O   . HOH   M 4 .   ? -7.324  -44.121 -48.690 1.000 45.879  0  334 HOH   C O   1 ? 
HETATM 4242 O  O   . HOH   M 4 .   ? -28.499 -32.308 -53.459 1.000 55.934  0  335 HOH   C O   1 ? 
HETATM 4243 O  O   . HOH   M 4 .   ? -17.850 -30.677 -41.454 1.000 42.804  0  336 HOH   C O   1 ? 
HETATM 4244 O  O   . HOH   M 4 .   ? -30.335 -46.922 -22.666 1.000 57.856  0  337 HOH   C O   1 ? 
HETATM 4245 O  O   . HOH   M 4 .   ? -18.920 -28.852 -59.827 1.000 64.433  0  338 HOH   C O   1 ? 
HETATM 4246 O  O   . HOH   M 4 .   ? -41.670 -48.360 -26.835 1.000 48.251  0  339 HOH   C O   1 ? 
# 
