data_9JOH
# 
_entry.id   9JOH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JOH         pdb_00009joh 10.2210/pdb9joh/pdb 
WWPDB D_1300051849 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JOH 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              changyg@ouc.edu.cn 
_pdbx_contact_author.name_first         Yaoguang 
_pdbx_contact_author.name_last          Chang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8234-7272 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chen, G.N.'  1 ? 
'Chang, Y.G.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Complex structure of endo-1.3-fucanase (Fun168D) with fucotetraose from Isostichopus badionotus at 1.36 Angstroms resulution.' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chen, G.N.'  1 ? 
primary 'Chang, Y.G.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man endo-1.3-fucanase 48005.340 2    ? ? ? ? 
2 branched syn 
;2-O-sulfo-alpha-L-fucopyranose-(1-3)-alpha-L-fucopyranose-(1-3)-2,4-di-O-sulfo-alpha-L-fucopyranose-(1-3)-2-O-sulfo-alpha-L-fucopyranose
;
922.833   2    ? ? ? ? 
3 water    nat water 18.015    1456 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSSTKNGIIELEQETEEELEQNQEIDYSNYPEFSWDTMPLYMHVRKNT
AYTDEEINYLASFPLITLEKSQAQNTYGSTEEGTLATASAIKLKNNKAKVLYYRNVVINWGNYKNDDEFISKNPSALLKN
QNNELVYMPNGSTPFFDITKSFVQEYWLKSVEDMVATPNIDGTFIDANIKVLVPSFFSSKVGVNKQAEIENSYFSMMSRL
KESLSNNLILANIIRVRPEFEENGLEYLGYFNGSYLEGFDSEAFGMSNAEYLVEGIEATQKAAQSGKIITMTLGLGEAID
NNTGIDDQREDVDLNDEELNKRVDYLLAIFLICAEKYSYVYLHDGYLATNSAVWLHQFDQYKKALGAPLGKAIKNGYIYT
RKFENLDVWLNLETQTATLTWKE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSSTKNGIIELEQETEEELEQNQEIDYSNYPEFSWDTMPLYMHVRKNT
AYTDEEINYLASFPLITLEKSQAQNTYGSTEEGTLATASAIKLKNNKAKVLYYRNVVINWGNYKNDDEFISKNPSALLKN
QNNELVYMPNGSTPFFDITKSFVQEYWLKSVEDMVATPNIDGTFIDANIKVLVPSFFSSKVGVNKQAEIENSYFSMMSRL
KESLSNNLILANIIRVRPEFEENGLEYLGYFNGSYLEGFDSEAFGMSNAEYLVEGIEATQKAAQSGKIITMTLGLGEAID
NNTGIDDQREDVDLNDEELNKRVDYLLAIFLICAEKYSYVYLHDGYLATNSAVWLHQFDQYKKALGAPLGKAIKNGYIYT
RKFENLDVWLNLETQTATLTWKE
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  ALA n 
1 23  SER n 
1 24  MET n 
1 25  THR n 
1 26  GLY n 
1 27  GLY n 
1 28  GLN n 
1 29  GLN n 
1 30  MET n 
1 31  GLY n 
1 32  ARG n 
1 33  GLY n 
1 34  SER n 
1 35  SER n 
1 36  THR n 
1 37  LYS n 
1 38  ASN n 
1 39  GLY n 
1 40  ILE n 
1 41  ILE n 
1 42  GLU n 
1 43  LEU n 
1 44  GLU n 
1 45  GLN n 
1 46  GLU n 
1 47  THR n 
1 48  GLU n 
1 49  GLU n 
1 50  GLU n 
1 51  LEU n 
1 52  GLU n 
1 53  GLN n 
1 54  ASN n 
1 55  GLN n 
1 56  GLU n 
1 57  ILE n 
1 58  ASP n 
1 59  TYR n 
1 60  SER n 
1 61  ASN n 
1 62  TYR n 
1 63  PRO n 
1 64  GLU n 
1 65  PHE n 
1 66  SER n 
1 67  TRP n 
1 68  ASP n 
1 69  THR n 
1 70  MET n 
1 71  PRO n 
1 72  LEU n 
1 73  TYR n 
1 74  MET n 
1 75  HIS n 
1 76  VAL n 
1 77  ARG n 
1 78  LYS n 
1 79  ASN n 
1 80  THR n 
1 81  ALA n 
1 82  TYR n 
1 83  THR n 
1 84  ASP n 
1 85  GLU n 
1 86  GLU n 
1 87  ILE n 
1 88  ASN n 
1 89  TYR n 
1 90  LEU n 
1 91  ALA n 
1 92  SER n 
1 93  PHE n 
1 94  PRO n 
1 95  LEU n 
1 96  ILE n 
1 97  THR n 
1 98  LEU n 
1 99  GLU n 
1 100 LYS n 
1 101 SER n 
1 102 GLN n 
1 103 ALA n 
1 104 GLN n 
1 105 ASN n 
1 106 THR n 
1 107 TYR n 
1 108 GLY n 
1 109 SER n 
1 110 THR n 
1 111 GLU n 
1 112 GLU n 
1 113 GLY n 
1 114 THR n 
1 115 LEU n 
1 116 ALA n 
1 117 THR n 
1 118 ALA n 
1 119 SER n 
1 120 ALA n 
1 121 ILE n 
1 122 LYS n 
1 123 LEU n 
1 124 LYS n 
1 125 ASN n 
1 126 ASN n 
1 127 LYS n 
1 128 ALA n 
1 129 LYS n 
1 130 VAL n 
1 131 LEU n 
1 132 TYR n 
1 133 TYR n 
1 134 ARG n 
1 135 ASN n 
1 136 VAL n 
1 137 VAL n 
1 138 ILE n 
1 139 ASN n 
1 140 TRP n 
1 141 GLY n 
1 142 ASN n 
1 143 TYR n 
1 144 LYS n 
1 145 ASN n 
1 146 ASP n 
1 147 ASP n 
1 148 GLU n 
1 149 PHE n 
1 150 ILE n 
1 151 SER n 
1 152 LYS n 
1 153 ASN n 
1 154 PRO n 
1 155 SER n 
1 156 ALA n 
1 157 LEU n 
1 158 LEU n 
1 159 LYS n 
1 160 ASN n 
1 161 GLN n 
1 162 ASN n 
1 163 ASN n 
1 164 GLU n 
1 165 LEU n 
1 166 VAL n 
1 167 TYR n 
1 168 MET n 
1 169 PRO n 
1 170 ASN n 
1 171 GLY n 
1 172 SER n 
1 173 THR n 
1 174 PRO n 
1 175 PHE n 
1 176 PHE n 
1 177 ASP n 
1 178 ILE n 
1 179 THR n 
1 180 LYS n 
1 181 SER n 
1 182 PHE n 
1 183 VAL n 
1 184 GLN n 
1 185 GLU n 
1 186 TYR n 
1 187 TRP n 
1 188 LEU n 
1 189 LYS n 
1 190 SER n 
1 191 VAL n 
1 192 GLU n 
1 193 ASP n 
1 194 MET n 
1 195 VAL n 
1 196 ALA n 
1 197 THR n 
1 198 PRO n 
1 199 ASN n 
1 200 ILE n 
1 201 ASP n 
1 202 GLY n 
1 203 THR n 
1 204 PHE n 
1 205 ILE n 
1 206 ASP n 
1 207 ALA n 
1 208 ASN n 
1 209 ILE n 
1 210 LYS n 
1 211 VAL n 
1 212 LEU n 
1 213 VAL n 
1 214 PRO n 
1 215 SER n 
1 216 PHE n 
1 217 PHE n 
1 218 SER n 
1 219 SER n 
1 220 LYS n 
1 221 VAL n 
1 222 GLY n 
1 223 VAL n 
1 224 ASN n 
1 225 LYS n 
1 226 GLN n 
1 227 ALA n 
1 228 GLU n 
1 229 ILE n 
1 230 GLU n 
1 231 ASN n 
1 232 SER n 
1 233 TYR n 
1 234 PHE n 
1 235 SER n 
1 236 MET n 
1 237 MET n 
1 238 SER n 
1 239 ARG n 
1 240 LEU n 
1 241 LYS n 
1 242 GLU n 
1 243 SER n 
1 244 LEU n 
1 245 SER n 
1 246 ASN n 
1 247 ASN n 
1 248 LEU n 
1 249 ILE n 
1 250 LEU n 
1 251 ALA n 
1 252 ASN n 
1 253 ILE n 
1 254 ILE n 
1 255 ARG n 
1 256 VAL n 
1 257 ARG n 
1 258 PRO n 
1 259 GLU n 
1 260 PHE n 
1 261 GLU n 
1 262 GLU n 
1 263 ASN n 
1 264 GLY n 
1 265 LEU n 
1 266 GLU n 
1 267 TYR n 
1 268 LEU n 
1 269 GLY n 
1 270 TYR n 
1 271 PHE n 
1 272 ASN n 
1 273 GLY n 
1 274 SER n 
1 275 TYR n 
1 276 LEU n 
1 277 GLU n 
1 278 GLY n 
1 279 PHE n 
1 280 ASP n 
1 281 SER n 
1 282 GLU n 
1 283 ALA n 
1 284 PHE n 
1 285 GLY n 
1 286 MET n 
1 287 SER n 
1 288 ASN n 
1 289 ALA n 
1 290 GLU n 
1 291 TYR n 
1 292 LEU n 
1 293 VAL n 
1 294 GLU n 
1 295 GLY n 
1 296 ILE n 
1 297 GLU n 
1 298 ALA n 
1 299 THR n 
1 300 GLN n 
1 301 LYS n 
1 302 ALA n 
1 303 ALA n 
1 304 GLN n 
1 305 SER n 
1 306 GLY n 
1 307 LYS n 
1 308 ILE n 
1 309 ILE n 
1 310 THR n 
1 311 MET n 
1 312 THR n 
1 313 LEU n 
1 314 GLY n 
1 315 LEU n 
1 316 GLY n 
1 317 GLU n 
1 318 ALA n 
1 319 ILE n 
1 320 ASP n 
1 321 ASN n 
1 322 ASN n 
1 323 THR n 
1 324 GLY n 
1 325 ILE n 
1 326 ASP n 
1 327 ASP n 
1 328 GLN n 
1 329 ARG n 
1 330 GLU n 
1 331 ASP n 
1 332 VAL n 
1 333 ASP n 
1 334 LEU n 
1 335 ASN n 
1 336 ASP n 
1 337 GLU n 
1 338 GLU n 
1 339 LEU n 
1 340 ASN n 
1 341 LYS n 
1 342 ARG n 
1 343 VAL n 
1 344 ASP n 
1 345 TYR n 
1 346 LEU n 
1 347 LEU n 
1 348 ALA n 
1 349 ILE n 
1 350 PHE n 
1 351 LEU n 
1 352 ILE n 
1 353 CYS n 
1 354 ALA n 
1 355 GLU n 
1 356 LYS n 
1 357 TYR n 
1 358 SER n 
1 359 TYR n 
1 360 VAL n 
1 361 TYR n 
1 362 LEU n 
1 363 HIS n 
1 364 ASP n 
1 365 GLY n 
1 366 TYR n 
1 367 LEU n 
1 368 ALA n 
1 369 THR n 
1 370 ASN n 
1 371 SER n 
1 372 ALA n 
1 373 VAL n 
1 374 TRP n 
1 375 LEU n 
1 376 HIS n 
1 377 GLN n 
1 378 PHE n 
1 379 ASP n 
1 380 GLN n 
1 381 TYR n 
1 382 LYS n 
1 383 LYS n 
1 384 ALA n 
1 385 LEU n 
1 386 GLY n 
1 387 ALA n 
1 388 PRO n 
1 389 LEU n 
1 390 GLY n 
1 391 LYS n 
1 392 ALA n 
1 393 ILE n 
1 394 LYS n 
1 395 ASN n 
1 396 GLY n 
1 397 TYR n 
1 398 ILE n 
1 399 TYR n 
1 400 THR n 
1 401 ARG n 
1 402 LYS n 
1 403 PHE n 
1 404 GLU n 
1 405 ASN n 
1 406 LEU n 
1 407 ASP n 
1 408 VAL n 
1 409 TRP n 
1 410 LEU n 
1 411 ASN n 
1 412 LEU n 
1 413 GLU n 
1 414 THR n 
1 415 GLN n 
1 416 THR n 
1 417 ALA n 
1 418 THR n 
1 419 LEU n 
1 420 THR n 
1 421 TRP n 
1 422 LYS n 
1 423 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   423 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 AXE80_08865 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Wenyingzhuangia fucanilytica' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1790137 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_branch.entity_id   2 
_pdbx_entity_branch.type        oligosaccharide 
# 
_pdbx_entity_branch_descriptor.ordinal           1 
_pdbx_entity_branch_descriptor.entity_id         2 
_pdbx_entity_branch_descriptor.descriptor        
'[][a-L-Fucp2SO3]{[(3+1)][a-L-Fucp2SO34SO3]{[(3+1)][a-L-Fucp]{[(3+1)][a-L-Fucp2SO3]{}}}}' 
_pdbx_entity_branch_descriptor.type              LINUCS 
_pdbx_entity_branch_descriptor.program           PDB-CARE 
_pdbx_entity_branch_descriptor.program_version   ? 
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 X2Y C1 O1 1 X6Y O3 HO3 sing ? 
2 2 3 FUC C1 O1 2 X2Y O3 HO3 sing ? 
3 2 4 X6Y C1 H1 3 FUC O3 HO3 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                             ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                            ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                          ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                     ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'           y CYSTEINE                            ? 'C3 H7 N O2 S'   121.158 
FUC 'L-saccharide, alpha linking' . alpha-L-fucopyranose                
'alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose' 'C6 H12 O5'      164.156 
GLN 'L-peptide linking'           y GLUTAMINE                           ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                     ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                             ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                           ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                               ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                          ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                             ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                              ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                          ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking'           y PHENYLALANINE                       ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                             ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                              ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                           ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                          ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                            ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                              ? 'C5 H11 N O2'    117.146 
X2Y 'L-saccharide, alpha linking' n 2,4-di-O-sulfo-alpha-L-fucopyranose 6-deoxy-2,4-di-O-sulfo-alpha-L-galactopyranose 
'C6 H12 O11 S2'  324.283 
X6Y 'L-saccharide, alpha linking' n 2-O-sulfo-alpha-L-fucopyranose      6-deoxy-2-O-sulfo-alpha-L-galactopyranose 'C6 H12 O8 S'    
244.220 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
FUC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LFucpa           
FUC 'COMMON NAME'                         GMML     1.0 a-L-fucopyranose 
FUC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Fucp         
FUC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fuc              
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -33 ?   ?   ?   A . n 
A 1 2   GLY 2   -32 ?   ?   ?   A . n 
A 1 3   SER 3   -31 ?   ?   ?   A . n 
A 1 4   SER 4   -30 ?   ?   ?   A . n 
A 1 5   HIS 5   -29 ?   ?   ?   A . n 
A 1 6   HIS 6   -28 ?   ?   ?   A . n 
A 1 7   HIS 7   -27 ?   ?   ?   A . n 
A 1 8   HIS 8   -26 ?   ?   ?   A . n 
A 1 9   HIS 9   -25 ?   ?   ?   A . n 
A 1 10  HIS 10  -24 ?   ?   ?   A . n 
A 1 11  SER 11  -23 ?   ?   ?   A . n 
A 1 12  SER 12  -22 ?   ?   ?   A . n 
A 1 13  GLY 13  -21 ?   ?   ?   A . n 
A 1 14  LEU 14  -20 ?   ?   ?   A . n 
A 1 15  VAL 15  -19 ?   ?   ?   A . n 
A 1 16  PRO 16  -18 ?   ?   ?   A . n 
A 1 17  ARG 17  -17 ?   ?   ?   A . n 
A 1 18  GLY 18  -16 ?   ?   ?   A . n 
A 1 19  SER 19  -15 ?   ?   ?   A . n 
A 1 20  HIS 20  -14 ?   ?   ?   A . n 
A 1 21  MET 21  -13 ?   ?   ?   A . n 
A 1 22  ALA 22  -12 ?   ?   ?   A . n 
A 1 23  SER 23  -11 ?   ?   ?   A . n 
A 1 24  MET 24  -10 ?   ?   ?   A . n 
A 1 25  THR 25  -9  ?   ?   ?   A . n 
A 1 26  GLY 26  -8  ?   ?   ?   A . n 
A 1 27  GLY 27  -7  ?   ?   ?   A . n 
A 1 28  GLN 28  -6  ?   ?   ?   A . n 
A 1 29  GLN 29  -5  ?   ?   ?   A . n 
A 1 30  MET 30  -4  ?   ?   ?   A . n 
A 1 31  GLY 31  -3  ?   ?   ?   A . n 
A 1 32  ARG 32  -2  ?   ?   ?   A . n 
A 1 33  GLY 33  -1  ?   ?   ?   A . n 
A 1 34  SER 34  0   ?   ?   ?   A . n 
A 1 35  SER 35  1   ?   ?   ?   A . n 
A 1 36  THR 36  2   ?   ?   ?   A . n 
A 1 37  LYS 37  3   ?   ?   ?   A . n 
A 1 38  ASN 38  4   ?   ?   ?   A . n 
A 1 39  GLY 39  5   ?   ?   ?   A . n 
A 1 40  ILE 40  6   ?   ?   ?   A . n 
A 1 41  ILE 41  7   ?   ?   ?   A . n 
A 1 42  GLU 42  8   ?   ?   ?   A . n 
A 1 43  LEU 43  9   ?   ?   ?   A . n 
A 1 44  GLU 44  10  ?   ?   ?   A . n 
A 1 45  GLN 45  11  ?   ?   ?   A . n 
A 1 46  GLU 46  12  ?   ?   ?   A . n 
A 1 47  THR 47  13  ?   ?   ?   A . n 
A 1 48  GLU 48  14  ?   ?   ?   A . n 
A 1 49  GLU 49  15  ?   ?   ?   A . n 
A 1 50  GLU 50  16  ?   ?   ?   A . n 
A 1 51  LEU 51  17  17  LEU LEU A . n 
A 1 52  GLU 52  18  18  GLU GLU A . n 
A 1 53  GLN 53  19  19  GLN GLN A . n 
A 1 54  ASN 54  20  20  ASN ASN A . n 
A 1 55  GLN 55  21  21  GLN GLN A . n 
A 1 56  GLU 56  22  22  GLU GLU A . n 
A 1 57  ILE 57  23  23  ILE ILE A . n 
A 1 58  ASP 58  24  24  ASP ASP A . n 
A 1 59  TYR 59  25  25  TYR TYR A . n 
A 1 60  SER 60  26  26  SER SER A . n 
A 1 61  ASN 61  27  27  ASN ASN A . n 
A 1 62  TYR 62  28  28  TYR TYR A . n 
A 1 63  PRO 63  29  29  PRO PRO A . n 
A 1 64  GLU 64  30  30  GLU GLU A . n 
A 1 65  PHE 65  31  31  PHE PHE A . n 
A 1 66  SER 66  32  32  SER SER A . n 
A 1 67  TRP 67  33  33  TRP TRP A . n 
A 1 68  ASP 68  34  34  ASP ASP A . n 
A 1 69  THR 69  35  35  THR THR A . n 
A 1 70  MET 70  36  36  MET MET A . n 
A 1 71  PRO 71  37  37  PRO PRO A . n 
A 1 72  LEU 72  38  38  LEU LEU A . n 
A 1 73  TYR 73  39  39  TYR TYR A . n 
A 1 74  MET 74  40  40  MET MET A . n 
A 1 75  HIS 75  41  41  HIS HIS A . n 
A 1 76  VAL 76  42  42  VAL VAL A . n 
A 1 77  ARG 77  43  43  ARG ARG A . n 
A 1 78  LYS 78  44  44  LYS LYS A . n 
A 1 79  ASN 79  45  45  ASN ASN A . n 
A 1 80  THR 80  46  46  THR THR A . n 
A 1 81  ALA 81  47  47  ALA ALA A . n 
A 1 82  TYR 82  48  48  TYR TYR A . n 
A 1 83  THR 83  49  49  THR THR A . n 
A 1 84  ASP 84  50  50  ASP ASP A . n 
A 1 85  GLU 85  51  51  GLU GLU A . n 
A 1 86  GLU 86  52  52  GLU GLU A . n 
A 1 87  ILE 87  53  53  ILE ILE A . n 
A 1 88  ASN 88  54  54  ASN ASN A . n 
A 1 89  TYR 89  55  55  TYR TYR A . n 
A 1 90  LEU 90  56  56  LEU LEU A . n 
A 1 91  ALA 91  57  57  ALA ALA A . n 
A 1 92  SER 92  58  58  SER SER A . n 
A 1 93  PHE 93  59  59  PHE PHE A . n 
A 1 94  PRO 94  60  60  PRO PRO A . n 
A 1 95  LEU 95  61  61  LEU LEU A . n 
A 1 96  ILE 96  62  62  ILE ILE A . n 
A 1 97  THR 97  63  63  THR THR A . n 
A 1 98  LEU 98  64  64  LEU LEU A . n 
A 1 99  GLU 99  65  65  GLU GLU A . n 
A 1 100 LYS 100 66  66  LYS LYS A . n 
A 1 101 SER 101 67  67  SER SER A . n 
A 1 102 GLN 102 68  68  GLN GLN A . n 
A 1 103 ALA 103 69  69  ALA ALA A . n 
A 1 104 GLN 104 70  70  GLN GLN A . n 
A 1 105 ASN 105 71  71  ASN ASN A . n 
A 1 106 THR 106 72  72  THR THR A . n 
A 1 107 TYR 107 73  73  TYR TYR A . n 
A 1 108 GLY 108 74  74  GLY GLY A . n 
A 1 109 SER 109 75  75  SER SER A . n 
A 1 110 THR 110 76  76  THR THR A . n 
A 1 111 GLU 111 77  77  GLU GLU A . n 
A 1 112 GLU 112 78  78  GLU GLU A . n 
A 1 113 GLY 113 79  79  GLY GLY A . n 
A 1 114 THR 114 80  80  THR THR A . n 
A 1 115 LEU 115 81  81  LEU LEU A . n 
A 1 116 ALA 116 82  82  ALA ALA A . n 
A 1 117 THR 117 83  83  THR THR A . n 
A 1 118 ALA 118 84  84  ALA ALA A . n 
A 1 119 SER 119 85  85  SER SER A . n 
A 1 120 ALA 120 86  86  ALA ALA A . n 
A 1 121 ILE 121 87  87  ILE ILE A . n 
A 1 122 LYS 122 88  88  LYS LYS A . n 
A 1 123 LEU 123 89  89  LEU LEU A . n 
A 1 124 LYS 124 90  90  LYS LYS A . n 
A 1 125 ASN 125 91  91  ASN ASN A . n 
A 1 126 ASN 126 92  92  ASN ASN A . n 
A 1 127 LYS 127 93  93  LYS LYS A . n 
A 1 128 ALA 128 94  94  ALA ALA A . n 
A 1 129 LYS 129 95  95  LYS LYS A . n 
A 1 130 VAL 130 96  96  VAL VAL A . n 
A 1 131 LEU 131 97  97  LEU LEU A . n 
A 1 132 TYR 132 98  98  TYR TYR A . n 
A 1 133 TYR 133 99  99  TYR TYR A . n 
A 1 134 ARG 134 100 100 ARG ARG A . n 
A 1 135 ASN 135 101 101 ASN ASN A . n 
A 1 136 VAL 136 102 102 VAL VAL A . n 
A 1 137 VAL 137 103 103 VAL VAL A . n 
A 1 138 ILE 138 104 104 ILE ILE A . n 
A 1 139 ASN 139 105 105 ASN ASN A . n 
A 1 140 TRP 140 106 106 TRP TRP A . n 
A 1 141 GLY 141 107 107 GLY GLY A . n 
A 1 142 ASN 142 108 108 ASN ASN A . n 
A 1 143 TYR 143 109 109 TYR TYR A . n 
A 1 144 LYS 144 110 110 LYS LYS A . n 
A 1 145 ASN 145 111 111 ASN ASN A . n 
A 1 146 ASP 146 112 112 ASP ASP A . n 
A 1 147 ASP 147 113 113 ASP ASP A . n 
A 1 148 GLU 148 114 114 GLU GLU A . n 
A 1 149 PHE 149 115 115 PHE PHE A . n 
A 1 150 ILE 150 116 116 ILE ILE A . n 
A 1 151 SER 151 117 117 SER SER A . n 
A 1 152 LYS 152 118 118 LYS LYS A . n 
A 1 153 ASN 153 119 119 ASN ASN A . n 
A 1 154 PRO 154 120 120 PRO PRO A . n 
A 1 155 SER 155 121 121 SER SER A . n 
A 1 156 ALA 156 122 122 ALA ALA A . n 
A 1 157 LEU 157 123 123 LEU LEU A . n 
A 1 158 LEU 158 124 124 LEU LEU A . n 
A 1 159 LYS 159 125 125 LYS LYS A . n 
A 1 160 ASN 160 126 126 ASN ASN A . n 
A 1 161 GLN 161 127 127 GLN GLN A . n 
A 1 162 ASN 162 128 128 ASN ASN A . n 
A 1 163 ASN 163 129 129 ASN ASN A . n 
A 1 164 GLU 164 130 130 GLU GLU A . n 
A 1 165 LEU 165 131 131 LEU LEU A . n 
A 1 166 VAL 166 132 132 VAL VAL A . n 
A 1 167 TYR 167 133 133 TYR TYR A . n 
A 1 168 MET 168 134 134 MET MET A . n 
A 1 169 PRO 169 135 135 PRO PRO A . n 
A 1 170 ASN 170 136 136 ASN ASN A . n 
A 1 171 GLY 171 137 137 GLY GLY A . n 
A 1 172 SER 172 138 138 SER SER A . n 
A 1 173 THR 173 139 139 THR THR A . n 
A 1 174 PRO 174 140 140 PRO PRO A . n 
A 1 175 PHE 175 141 141 PHE PHE A . n 
A 1 176 PHE 176 142 142 PHE PHE A . n 
A 1 177 ASP 177 143 143 ASP ASP A . n 
A 1 178 ILE 178 144 144 ILE ILE A . n 
A 1 179 THR 179 145 145 THR THR A . n 
A 1 180 LYS 180 146 146 LYS LYS A . n 
A 1 181 SER 181 147 147 SER SER A . n 
A 1 182 PHE 182 148 148 PHE PHE A . n 
A 1 183 VAL 183 149 149 VAL VAL A . n 
A 1 184 GLN 184 150 150 GLN GLN A . n 
A 1 185 GLU 185 151 151 GLU GLU A . n 
A 1 186 TYR 186 152 152 TYR TYR A . n 
A 1 187 TRP 187 153 153 TRP TRP A . n 
A 1 188 LEU 188 154 154 LEU LEU A . n 
A 1 189 LYS 189 155 155 LYS LYS A . n 
A 1 190 SER 190 156 156 SER SER A . n 
A 1 191 VAL 191 157 157 VAL VAL A . n 
A 1 192 GLU 192 158 158 GLU GLU A . n 
A 1 193 ASP 193 159 159 ASP ASP A . n 
A 1 194 MET 194 160 160 MET MET A . n 
A 1 195 VAL 195 161 161 VAL VAL A . n 
A 1 196 ALA 196 162 162 ALA ALA A . n 
A 1 197 THR 197 163 163 THR THR A . n 
A 1 198 PRO 198 164 164 PRO PRO A . n 
A 1 199 ASN 199 165 165 ASN ASN A . n 
A 1 200 ILE 200 166 166 ILE ILE A . n 
A 1 201 ASP 201 167 167 ASP ASP A . n 
A 1 202 GLY 202 168 168 GLY GLY A . n 
A 1 203 THR 203 169 169 THR THR A . n 
A 1 204 PHE 204 170 170 PHE PHE A . n 
A 1 205 ILE 205 171 171 ILE ILE A . n 
A 1 206 ASP 206 172 172 ASP ASP A . n 
A 1 207 ALA 207 173 173 ALA ALA A . n 
A 1 208 ASN 208 174 174 ASN ASN A . n 
A 1 209 ILE 209 175 175 ILE ILE A . n 
A 1 210 LYS 210 176 176 LYS LYS A . n 
A 1 211 VAL 211 177 177 VAL VAL A . n 
A 1 212 LEU 212 178 178 LEU LEU A . n 
A 1 213 VAL 213 179 179 VAL VAL A . n 
A 1 214 PRO 214 180 180 PRO PRO A . n 
A 1 215 SER 215 181 181 SER SER A . n 
A 1 216 PHE 216 182 182 PHE PHE A . n 
A 1 217 PHE 217 183 183 PHE PHE A . n 
A 1 218 SER 218 184 184 SER SER A . n 
A 1 219 SER 219 185 185 SER SER A . n 
A 1 220 LYS 220 186 186 LYS LYS A . n 
A 1 221 VAL 221 187 187 VAL VAL A . n 
A 1 222 GLY 222 188 188 GLY GLY A . n 
A 1 223 VAL 223 189 189 VAL VAL A . n 
A 1 224 ASN 224 190 190 ASN ASN A . n 
A 1 225 LYS 225 191 191 LYS LYS A . n 
A 1 226 GLN 226 192 192 GLN GLN A . n 
A 1 227 ALA 227 193 193 ALA ALA A . n 
A 1 228 GLU 228 194 194 GLU GLU A . n 
A 1 229 ILE 229 195 195 ILE ILE A . n 
A 1 230 GLU 230 196 196 GLU GLU A . n 
A 1 231 ASN 231 197 197 ASN ASN A . n 
A 1 232 SER 232 198 198 SER SER A . n 
A 1 233 TYR 233 199 199 TYR TYR A . n 
A 1 234 PHE 234 200 200 PHE PHE A . n 
A 1 235 SER 235 201 201 SER SER A . n 
A 1 236 MET 236 202 202 MET MET A . n 
A 1 237 MET 237 203 203 MET MET A . n 
A 1 238 SER 238 204 204 SER SER A . n 
A 1 239 ARG 239 205 205 ARG ARG A . n 
A 1 240 LEU 240 206 206 LEU LEU A . n 
A 1 241 LYS 241 207 207 LYS LYS A . n 
A 1 242 GLU 242 208 208 GLU GLU A . n 
A 1 243 SER 243 209 209 SER SER A . n 
A 1 244 LEU 244 210 210 LEU LEU A . n 
A 1 245 SER 245 211 211 SER SER A . n 
A 1 246 ASN 246 212 212 ASN ASN A . n 
A 1 247 ASN 247 213 213 ASN ASN A . n 
A 1 248 LEU 248 214 214 LEU LEU A . n 
A 1 249 ILE 249 215 215 ILE ILE A . n 
A 1 250 LEU 250 216 216 LEU LEU A . n 
A 1 251 ALA 251 217 217 ALA ALA A . n 
A 1 252 ASN 252 218 218 ASN ASN A . n 
A 1 253 ILE 253 219 219 ILE ILE A . n 
A 1 254 ILE 254 220 220 ILE ILE A . n 
A 1 255 ARG 255 221 221 ARG ARG A . n 
A 1 256 VAL 256 222 222 VAL VAL A . n 
A 1 257 ARG 257 223 223 ARG ARG A . n 
A 1 258 PRO 258 224 224 PRO PRO A . n 
A 1 259 GLU 259 225 225 GLU GLU A . n 
A 1 260 PHE 260 226 226 PHE PHE A . n 
A 1 261 GLU 261 227 227 GLU GLU A . n 
A 1 262 GLU 262 228 228 GLU GLU A . n 
A 1 263 ASN 263 229 229 ASN ASN A . n 
A 1 264 GLY 264 230 230 GLY GLY A . n 
A 1 265 LEU 265 231 231 LEU LEU A . n 
A 1 266 GLU 266 232 232 GLU GLU A . n 
A 1 267 TYR 267 233 233 TYR TYR A . n 
A 1 268 LEU 268 234 234 LEU LEU A . n 
A 1 269 GLY 269 235 235 GLY GLY A . n 
A 1 270 TYR 270 236 236 TYR TYR A . n 
A 1 271 PHE 271 237 237 PHE PHE A . n 
A 1 272 ASN 272 238 238 ASN ASN A . n 
A 1 273 GLY 273 239 239 GLY GLY A . n 
A 1 274 SER 274 240 240 SER SER A . n 
A 1 275 TYR 275 241 241 TYR TYR A . n 
A 1 276 LEU 276 242 242 LEU LEU A . n 
A 1 277 GLU 277 243 243 GLU GLU A . n 
A 1 278 GLY 278 244 244 GLY GLY A . n 
A 1 279 PHE 279 245 245 PHE PHE A . n 
A 1 280 ASP 280 246 246 ASP ASP A . n 
A 1 281 SER 281 247 247 SER SER A . n 
A 1 282 GLU 282 248 248 GLU GLU A . n 
A 1 283 ALA 283 249 249 ALA ALA A . n 
A 1 284 PHE 284 250 250 PHE PHE A . n 
A 1 285 GLY 285 251 251 GLY GLY A . n 
A 1 286 MET 286 252 252 MET MET A . n 
A 1 287 SER 287 253 253 SER SER A . n 
A 1 288 ASN 288 254 254 ASN ASN A . n 
A 1 289 ALA 289 255 255 ALA ALA A . n 
A 1 290 GLU 290 256 256 GLU GLU A . n 
A 1 291 TYR 291 257 257 TYR TYR A . n 
A 1 292 LEU 292 258 258 LEU LEU A . n 
A 1 293 VAL 293 259 259 VAL VAL A . n 
A 1 294 GLU 294 260 260 GLU GLU A . n 
A 1 295 GLY 295 261 261 GLY GLY A . n 
A 1 296 ILE 296 262 262 ILE ILE A . n 
A 1 297 GLU 297 263 263 GLU GLU A . n 
A 1 298 ALA 298 264 264 ALA ALA A . n 
A 1 299 THR 299 265 265 THR THR A . n 
A 1 300 GLN 300 266 266 GLN GLN A . n 
A 1 301 LYS 301 267 267 LYS LYS A . n 
A 1 302 ALA 302 268 268 ALA ALA A . n 
A 1 303 ALA 303 269 269 ALA ALA A . n 
A 1 304 GLN 304 270 270 GLN GLN A . n 
A 1 305 SER 305 271 271 SER SER A . n 
A 1 306 GLY 306 272 272 GLY GLY A . n 
A 1 307 LYS 307 273 273 LYS LYS A . n 
A 1 308 ILE 308 274 274 ILE ILE A . n 
A 1 309 ILE 309 275 275 ILE ILE A . n 
A 1 310 THR 310 276 276 THR THR A . n 
A 1 311 MET 311 277 277 MET MET A . n 
A 1 312 THR 312 278 278 THR THR A . n 
A 1 313 LEU 313 279 279 LEU LEU A . n 
A 1 314 GLY 314 280 280 GLY GLY A . n 
A 1 315 LEU 315 281 281 LEU LEU A . n 
A 1 316 GLY 316 282 282 GLY GLY A . n 
A 1 317 GLU 317 283 283 GLU GLU A . n 
A 1 318 ALA 318 284 284 ALA ALA A . n 
A 1 319 ILE 319 285 285 ILE ILE A . n 
A 1 320 ASP 320 286 286 ASP ASP A . n 
A 1 321 ASN 321 287 287 ASN ASN A . n 
A 1 322 ASN 322 288 288 ASN ASN A . n 
A 1 323 THR 323 289 289 THR THR A . n 
A 1 324 GLY 324 290 290 GLY GLY A . n 
A 1 325 ILE 325 291 291 ILE ILE A . n 
A 1 326 ASP 326 292 292 ASP ASP A . n 
A 1 327 ASP 327 293 293 ASP ASP A . n 
A 1 328 GLN 328 294 294 GLN GLN A . n 
A 1 329 ARG 329 295 295 ARG ARG A . n 
A 1 330 GLU 330 296 296 GLU GLU A . n 
A 1 331 ASP 331 297 297 ASP ASP A . n 
A 1 332 VAL 332 298 298 VAL VAL A . n 
A 1 333 ASP 333 299 299 ASP ASP A . n 
A 1 334 LEU 334 300 300 LEU LEU A . n 
A 1 335 ASN 335 301 301 ASN ASN A . n 
A 1 336 ASP 336 302 302 ASP ASP A . n 
A 1 337 GLU 337 303 303 GLU GLU A . n 
A 1 338 GLU 338 304 304 GLU GLU A . n 
A 1 339 LEU 339 305 305 LEU LEU A . n 
A 1 340 ASN 340 306 306 ASN ASN A . n 
A 1 341 LYS 341 307 307 LYS LYS A . n 
A 1 342 ARG 342 308 308 ARG ARG A . n 
A 1 343 VAL 343 309 309 VAL VAL A . n 
A 1 344 ASP 344 310 310 ASP ASP A . n 
A 1 345 TYR 345 311 311 TYR TYR A . n 
A 1 346 LEU 346 312 312 LEU LEU A . n 
A 1 347 LEU 347 313 313 LEU LEU A . n 
A 1 348 ALA 348 314 314 ALA ALA A . n 
A 1 349 ILE 349 315 315 ILE ILE A . n 
A 1 350 PHE 350 316 316 PHE PHE A . n 
A 1 351 LEU 351 317 317 LEU LEU A . n 
A 1 352 ILE 352 318 318 ILE ILE A . n 
A 1 353 CYS 353 319 319 CYS CYS A . n 
A 1 354 ALA 354 320 320 ALA ALA A . n 
A 1 355 GLU 355 321 321 GLU GLU A . n 
A 1 356 LYS 356 322 322 LYS LYS A . n 
A 1 357 TYR 357 323 323 TYR TYR A . n 
A 1 358 SER 358 324 324 SER SER A . n 
A 1 359 TYR 359 325 325 TYR TYR A . n 
A 1 360 VAL 360 326 326 VAL VAL A . n 
A 1 361 TYR 361 327 327 TYR TYR A . n 
A 1 362 LEU 362 328 328 LEU LEU A . n 
A 1 363 HIS 363 329 329 HIS HIS A . n 
A 1 364 ASP 364 330 330 ASP ASP A . n 
A 1 365 GLY 365 331 331 GLY GLY A . n 
A 1 366 TYR 366 332 332 TYR TYR A . n 
A 1 367 LEU 367 333 333 LEU LEU A . n 
A 1 368 ALA 368 334 334 ALA ALA A . n 
A 1 369 THR 369 335 335 THR THR A . n 
A 1 370 ASN 370 336 336 ASN ASN A . n 
A 1 371 SER 371 337 337 SER SER A . n 
A 1 372 ALA 372 338 338 ALA ALA A . n 
A 1 373 VAL 373 339 339 VAL VAL A . n 
A 1 374 TRP 374 340 340 TRP TRP A . n 
A 1 375 LEU 375 341 341 LEU LEU A . n 
A 1 376 HIS 376 342 342 HIS HIS A . n 
A 1 377 GLN 377 343 343 GLN GLN A . n 
A 1 378 PHE 378 344 344 PHE PHE A . n 
A 1 379 ASP 379 345 345 ASP ASP A . n 
A 1 380 GLN 380 346 346 GLN GLN A . n 
A 1 381 TYR 381 347 347 TYR TYR A . n 
A 1 382 LYS 382 348 348 LYS LYS A . n 
A 1 383 LYS 383 349 349 LYS LYS A . n 
A 1 384 ALA 384 350 350 ALA ALA A . n 
A 1 385 LEU 385 351 351 LEU LEU A . n 
A 1 386 GLY 386 352 352 GLY GLY A . n 
A 1 387 ALA 387 353 353 ALA ALA A . n 
A 1 388 PRO 388 354 354 PRO PRO A . n 
A 1 389 LEU 389 355 355 LEU LEU A . n 
A 1 390 GLY 390 356 356 GLY GLY A . n 
A 1 391 LYS 391 357 357 LYS LYS A . n 
A 1 392 ALA 392 358 358 ALA ALA A . n 
A 1 393 ILE 393 359 359 ILE ILE A . n 
A 1 394 LYS 394 360 360 LYS LYS A . n 
A 1 395 ASN 395 361 361 ASN ASN A . n 
A 1 396 GLY 396 362 362 GLY GLY A . n 
A 1 397 TYR 397 363 363 TYR TYR A . n 
A 1 398 ILE 398 364 364 ILE ILE A . n 
A 1 399 TYR 399 365 365 TYR TYR A . n 
A 1 400 THR 400 366 366 THR THR A . n 
A 1 401 ARG 401 367 367 ARG ARG A . n 
A 1 402 LYS 402 368 368 LYS LYS A . n 
A 1 403 PHE 403 369 369 PHE PHE A . n 
A 1 404 GLU 404 370 370 GLU GLU A . n 
A 1 405 ASN 405 371 371 ASN ASN A . n 
A 1 406 LEU 406 372 372 LEU LEU A . n 
A 1 407 ASP 407 373 373 ASP ASP A . n 
A 1 408 VAL 408 374 374 VAL VAL A . n 
A 1 409 TRP 409 375 375 TRP TRP A . n 
A 1 410 LEU 410 376 376 LEU LEU A . n 
A 1 411 ASN 411 377 377 ASN ASN A . n 
A 1 412 LEU 412 378 378 LEU LEU A . n 
A 1 413 GLU 413 379 379 GLU GLU A . n 
A 1 414 THR 414 380 380 THR THR A . n 
A 1 415 GLN 415 381 381 GLN GLN A . n 
A 1 416 THR 416 382 382 THR THR A . n 
A 1 417 ALA 417 383 383 ALA ALA A . n 
A 1 418 THR 418 384 384 THR THR A . n 
A 1 419 LEU 419 385 385 LEU LEU A . n 
A 1 420 THR 420 386 386 THR THR A . n 
A 1 421 TRP 421 387 387 TRP TRP A . n 
A 1 422 LYS 422 388 388 LYS LYS A . n 
A 1 423 GLU 423 389 ?   ?   ?   A . n 
B 1 1   MET 1   -33 ?   ?   ?   B . n 
B 1 2   GLY 2   -32 ?   ?   ?   B . n 
B 1 3   SER 3   -31 ?   ?   ?   B . n 
B 1 4   SER 4   -30 ?   ?   ?   B . n 
B 1 5   HIS 5   -29 ?   ?   ?   B . n 
B 1 6   HIS 6   -28 ?   ?   ?   B . n 
B 1 7   HIS 7   -27 ?   ?   ?   B . n 
B 1 8   HIS 8   -26 ?   ?   ?   B . n 
B 1 9   HIS 9   -25 ?   ?   ?   B . n 
B 1 10  HIS 10  -24 ?   ?   ?   B . n 
B 1 11  SER 11  -23 ?   ?   ?   B . n 
B 1 12  SER 12  -22 ?   ?   ?   B . n 
B 1 13  GLY 13  -21 ?   ?   ?   B . n 
B 1 14  LEU 14  -20 ?   ?   ?   B . n 
B 1 15  VAL 15  -19 ?   ?   ?   B . n 
B 1 16  PRO 16  -18 ?   ?   ?   B . n 
B 1 17  ARG 17  -17 ?   ?   ?   B . n 
B 1 18  GLY 18  -16 ?   ?   ?   B . n 
B 1 19  SER 19  -15 ?   ?   ?   B . n 
B 1 20  HIS 20  -14 ?   ?   ?   B . n 
B 1 21  MET 21  -13 ?   ?   ?   B . n 
B 1 22  ALA 22  -12 ?   ?   ?   B . n 
B 1 23  SER 23  -11 ?   ?   ?   B . n 
B 1 24  MET 24  -10 ?   ?   ?   B . n 
B 1 25  THR 25  -9  ?   ?   ?   B . n 
B 1 26  GLY 26  -8  ?   ?   ?   B . n 
B 1 27  GLY 27  -7  ?   ?   ?   B . n 
B 1 28  GLN 28  -6  ?   ?   ?   B . n 
B 1 29  GLN 29  -5  ?   ?   ?   B . n 
B 1 30  MET 30  -4  ?   ?   ?   B . n 
B 1 31  GLY 31  -3  ?   ?   ?   B . n 
B 1 32  ARG 32  -2  ?   ?   ?   B . n 
B 1 33  GLY 33  -1  ?   ?   ?   B . n 
B 1 34  SER 34  0   ?   ?   ?   B . n 
B 1 35  SER 35  1   ?   ?   ?   B . n 
B 1 36  THR 36  2   ?   ?   ?   B . n 
B 1 37  LYS 37  3   ?   ?   ?   B . n 
B 1 38  ASN 38  4   ?   ?   ?   B . n 
B 1 39  GLY 39  5   ?   ?   ?   B . n 
B 1 40  ILE 40  6   ?   ?   ?   B . n 
B 1 41  ILE 41  7   ?   ?   ?   B . n 
B 1 42  GLU 42  8   ?   ?   ?   B . n 
B 1 43  LEU 43  9   ?   ?   ?   B . n 
B 1 44  GLU 44  10  ?   ?   ?   B . n 
B 1 45  GLN 45  11  ?   ?   ?   B . n 
B 1 46  GLU 46  12  ?   ?   ?   B . n 
B 1 47  THR 47  13  ?   ?   ?   B . n 
B 1 48  GLU 48  14  ?   ?   ?   B . n 
B 1 49  GLU 49  15  ?   ?   ?   B . n 
B 1 50  GLU 50  16  ?   ?   ?   B . n 
B 1 51  LEU 51  17  ?   ?   ?   B . n 
B 1 52  GLU 52  18  ?   ?   ?   B . n 
B 1 53  GLN 53  19  ?   ?   ?   B . n 
B 1 54  ASN 54  20  ?   ?   ?   B . n 
B 1 55  GLN 55  21  ?   ?   ?   B . n 
B 1 56  GLU 56  22  ?   ?   ?   B . n 
B 1 57  ILE 57  23  23  ILE ILE B . n 
B 1 58  ASP 58  24  24  ASP ASP B . n 
B 1 59  TYR 59  25  25  TYR TYR B . n 
B 1 60  SER 60  26  26  SER SER B . n 
B 1 61  ASN 61  27  27  ASN ASN B . n 
B 1 62  TYR 62  28  28  TYR TYR B . n 
B 1 63  PRO 63  29  29  PRO PRO B . n 
B 1 64  GLU 64  30  30  GLU GLU B . n 
B 1 65  PHE 65  31  31  PHE PHE B . n 
B 1 66  SER 66  32  32  SER SER B . n 
B 1 67  TRP 67  33  33  TRP TRP B . n 
B 1 68  ASP 68  34  34  ASP ASP B . n 
B 1 69  THR 69  35  35  THR THR B . n 
B 1 70  MET 70  36  36  MET MET B . n 
B 1 71  PRO 71  37  37  PRO PRO B . n 
B 1 72  LEU 72  38  38  LEU LEU B . n 
B 1 73  TYR 73  39  39  TYR TYR B . n 
B 1 74  MET 74  40  40  MET MET B . n 
B 1 75  HIS 75  41  41  HIS HIS B . n 
B 1 76  VAL 76  42  42  VAL VAL B . n 
B 1 77  ARG 77  43  43  ARG ARG B . n 
B 1 78  LYS 78  44  44  LYS LYS B . n 
B 1 79  ASN 79  45  45  ASN ASN B . n 
B 1 80  THR 80  46  46  THR THR B . n 
B 1 81  ALA 81  47  47  ALA ALA B . n 
B 1 82  TYR 82  48  48  TYR TYR B . n 
B 1 83  THR 83  49  49  THR THR B . n 
B 1 84  ASP 84  50  50  ASP ASP B . n 
B 1 85  GLU 85  51  51  GLU GLU B . n 
B 1 86  GLU 86  52  52  GLU GLU B . n 
B 1 87  ILE 87  53  53  ILE ILE B . n 
B 1 88  ASN 88  54  54  ASN ASN B . n 
B 1 89  TYR 89  55  55  TYR TYR B . n 
B 1 90  LEU 90  56  56  LEU LEU B . n 
B 1 91  ALA 91  57  57  ALA ALA B . n 
B 1 92  SER 92  58  58  SER SER B . n 
B 1 93  PHE 93  59  59  PHE PHE B . n 
B 1 94  PRO 94  60  60  PRO PRO B . n 
B 1 95  LEU 95  61  61  LEU LEU B . n 
B 1 96  ILE 96  62  62  ILE ILE B . n 
B 1 97  THR 97  63  63  THR THR B . n 
B 1 98  LEU 98  64  64  LEU LEU B . n 
B 1 99  GLU 99  65  65  GLU GLU B . n 
B 1 100 LYS 100 66  66  LYS LYS B . n 
B 1 101 SER 101 67  67  SER SER B . n 
B 1 102 GLN 102 68  68  GLN GLN B . n 
B 1 103 ALA 103 69  69  ALA ALA B . n 
B 1 104 GLN 104 70  70  GLN GLN B . n 
B 1 105 ASN 105 71  71  ASN ASN B . n 
B 1 106 THR 106 72  72  THR THR B . n 
B 1 107 TYR 107 73  73  TYR TYR B . n 
B 1 108 GLY 108 74  74  GLY GLY B . n 
B 1 109 SER 109 75  75  SER SER B . n 
B 1 110 THR 110 76  76  THR THR B . n 
B 1 111 GLU 111 77  77  GLU GLU B . n 
B 1 112 GLU 112 78  78  GLU GLU B . n 
B 1 113 GLY 113 79  79  GLY GLY B . n 
B 1 114 THR 114 80  80  THR THR B . n 
B 1 115 LEU 115 81  81  LEU LEU B . n 
B 1 116 ALA 116 82  82  ALA ALA B . n 
B 1 117 THR 117 83  83  THR THR B . n 
B 1 118 ALA 118 84  84  ALA ALA B . n 
B 1 119 SER 119 85  85  SER SER B . n 
B 1 120 ALA 120 86  86  ALA ALA B . n 
B 1 121 ILE 121 87  87  ILE ILE B . n 
B 1 122 LYS 122 88  88  LYS LYS B . n 
B 1 123 LEU 123 89  89  LEU LEU B . n 
B 1 124 LYS 124 90  90  LYS LYS B . n 
B 1 125 ASN 125 91  91  ASN ASN B . n 
B 1 126 ASN 126 92  92  ASN ASN B . n 
B 1 127 LYS 127 93  93  LYS LYS B . n 
B 1 128 ALA 128 94  94  ALA ALA B . n 
B 1 129 LYS 129 95  95  LYS LYS B . n 
B 1 130 VAL 130 96  96  VAL VAL B . n 
B 1 131 LEU 131 97  97  LEU LEU B . n 
B 1 132 TYR 132 98  98  TYR TYR B . n 
B 1 133 TYR 133 99  99  TYR TYR B . n 
B 1 134 ARG 134 100 100 ARG ARG B . n 
B 1 135 ASN 135 101 101 ASN ASN B . n 
B 1 136 VAL 136 102 102 VAL VAL B . n 
B 1 137 VAL 137 103 103 VAL VAL B . n 
B 1 138 ILE 138 104 104 ILE ILE B . n 
B 1 139 ASN 139 105 105 ASN ASN B . n 
B 1 140 TRP 140 106 106 TRP TRP B . n 
B 1 141 GLY 141 107 107 GLY GLY B . n 
B 1 142 ASN 142 108 108 ASN ASN B . n 
B 1 143 TYR 143 109 109 TYR TYR B . n 
B 1 144 LYS 144 110 110 LYS LYS B . n 
B 1 145 ASN 145 111 111 ASN ASN B . n 
B 1 146 ASP 146 112 112 ASP ASP B . n 
B 1 147 ASP 147 113 113 ASP ASP B . n 
B 1 148 GLU 148 114 114 GLU GLU B . n 
B 1 149 PHE 149 115 115 PHE PHE B . n 
B 1 150 ILE 150 116 116 ILE ILE B . n 
B 1 151 SER 151 117 117 SER SER B . n 
B 1 152 LYS 152 118 118 LYS LYS B . n 
B 1 153 ASN 153 119 119 ASN ASN B . n 
B 1 154 PRO 154 120 120 PRO PRO B . n 
B 1 155 SER 155 121 121 SER SER B . n 
B 1 156 ALA 156 122 122 ALA ALA B . n 
B 1 157 LEU 157 123 123 LEU LEU B . n 
B 1 158 LEU 158 124 124 LEU LEU B . n 
B 1 159 LYS 159 125 125 LYS LYS B . n 
B 1 160 ASN 160 126 126 ASN ASN B . n 
B 1 161 GLN 161 127 127 GLN GLN B . n 
B 1 162 ASN 162 128 128 ASN ASN B . n 
B 1 163 ASN 163 129 129 ASN ASN B . n 
B 1 164 GLU 164 130 130 GLU GLU B . n 
B 1 165 LEU 165 131 131 LEU LEU B . n 
B 1 166 VAL 166 132 132 VAL VAL B . n 
B 1 167 TYR 167 133 133 TYR TYR B . n 
B 1 168 MET 168 134 134 MET MET B . n 
B 1 169 PRO 169 135 135 PRO PRO B . n 
B 1 170 ASN 170 136 136 ASN ASN B . n 
B 1 171 GLY 171 137 137 GLY GLY B . n 
B 1 172 SER 172 138 138 SER SER B . n 
B 1 173 THR 173 139 139 THR THR B . n 
B 1 174 PRO 174 140 140 PRO PRO B . n 
B 1 175 PHE 175 141 141 PHE PHE B . n 
B 1 176 PHE 176 142 142 PHE PHE B . n 
B 1 177 ASP 177 143 143 ASP ASP B . n 
B 1 178 ILE 178 144 144 ILE ILE B . n 
B 1 179 THR 179 145 145 THR THR B . n 
B 1 180 LYS 180 146 146 LYS LYS B . n 
B 1 181 SER 181 147 147 SER SER B . n 
B 1 182 PHE 182 148 148 PHE PHE B . n 
B 1 183 VAL 183 149 149 VAL VAL B . n 
B 1 184 GLN 184 150 150 GLN GLN B . n 
B 1 185 GLU 185 151 151 GLU GLU B . n 
B 1 186 TYR 186 152 152 TYR TYR B . n 
B 1 187 TRP 187 153 153 TRP TRP B . n 
B 1 188 LEU 188 154 154 LEU LEU B . n 
B 1 189 LYS 189 155 155 LYS LYS B . n 
B 1 190 SER 190 156 156 SER SER B . n 
B 1 191 VAL 191 157 157 VAL VAL B . n 
B 1 192 GLU 192 158 158 GLU GLU B . n 
B 1 193 ASP 193 159 159 ASP ASP B . n 
B 1 194 MET 194 160 160 MET MET B . n 
B 1 195 VAL 195 161 161 VAL VAL B . n 
B 1 196 ALA 196 162 162 ALA ALA B . n 
B 1 197 THR 197 163 163 THR THR B . n 
B 1 198 PRO 198 164 164 PRO PRO B . n 
B 1 199 ASN 199 165 165 ASN ASN B . n 
B 1 200 ILE 200 166 166 ILE ILE B . n 
B 1 201 ASP 201 167 167 ASP ASP B . n 
B 1 202 GLY 202 168 168 GLY GLY B . n 
B 1 203 THR 203 169 169 THR THR B . n 
B 1 204 PHE 204 170 170 PHE PHE B . n 
B 1 205 ILE 205 171 171 ILE ILE B . n 
B 1 206 ASP 206 172 172 ASP ASP B . n 
B 1 207 ALA 207 173 173 ALA ALA B . n 
B 1 208 ASN 208 174 174 ASN ASN B . n 
B 1 209 ILE 209 175 175 ILE ILE B . n 
B 1 210 LYS 210 176 176 LYS LYS B . n 
B 1 211 VAL 211 177 177 VAL VAL B . n 
B 1 212 LEU 212 178 178 LEU LEU B . n 
B 1 213 VAL 213 179 179 VAL VAL B . n 
B 1 214 PRO 214 180 180 PRO PRO B . n 
B 1 215 SER 215 181 181 SER SER B . n 
B 1 216 PHE 216 182 182 PHE PHE B . n 
B 1 217 PHE 217 183 183 PHE PHE B . n 
B 1 218 SER 218 184 184 SER SER B . n 
B 1 219 SER 219 185 185 SER SER B . n 
B 1 220 LYS 220 186 186 LYS LYS B . n 
B 1 221 VAL 221 187 187 VAL VAL B . n 
B 1 222 GLY 222 188 188 GLY GLY B . n 
B 1 223 VAL 223 189 189 VAL VAL B . n 
B 1 224 ASN 224 190 190 ASN ASN B . n 
B 1 225 LYS 225 191 191 LYS LYS B . n 
B 1 226 GLN 226 192 192 GLN GLN B . n 
B 1 227 ALA 227 193 193 ALA ALA B . n 
B 1 228 GLU 228 194 194 GLU GLU B . n 
B 1 229 ILE 229 195 195 ILE ILE B . n 
B 1 230 GLU 230 196 196 GLU GLU B . n 
B 1 231 ASN 231 197 197 ASN ASN B . n 
B 1 232 SER 232 198 198 SER SER B . n 
B 1 233 TYR 233 199 199 TYR TYR B . n 
B 1 234 PHE 234 200 200 PHE PHE B . n 
B 1 235 SER 235 201 201 SER SER B . n 
B 1 236 MET 236 202 202 MET MET B . n 
B 1 237 MET 237 203 203 MET MET B . n 
B 1 238 SER 238 204 204 SER SER B . n 
B 1 239 ARG 239 205 205 ARG ARG B . n 
B 1 240 LEU 240 206 206 LEU LEU B . n 
B 1 241 LYS 241 207 207 LYS LYS B . n 
B 1 242 GLU 242 208 208 GLU GLU B . n 
B 1 243 SER 243 209 209 SER SER B . n 
B 1 244 LEU 244 210 210 LEU LEU B . n 
B 1 245 SER 245 211 211 SER SER B . n 
B 1 246 ASN 246 212 212 ASN ASN B . n 
B 1 247 ASN 247 213 213 ASN ASN B . n 
B 1 248 LEU 248 214 214 LEU LEU B . n 
B 1 249 ILE 249 215 215 ILE ILE B . n 
B 1 250 LEU 250 216 216 LEU LEU B . n 
B 1 251 ALA 251 217 217 ALA ALA B . n 
B 1 252 ASN 252 218 218 ASN ASN B . n 
B 1 253 ILE 253 219 219 ILE ILE B . n 
B 1 254 ILE 254 220 220 ILE ILE B . n 
B 1 255 ARG 255 221 221 ARG ARG B . n 
B 1 256 VAL 256 222 222 VAL VAL B . n 
B 1 257 ARG 257 223 223 ARG ARG B . n 
B 1 258 PRO 258 224 224 PRO PRO B . n 
B 1 259 GLU 259 225 225 GLU GLU B . n 
B 1 260 PHE 260 226 226 PHE PHE B . n 
B 1 261 GLU 261 227 227 GLU GLU B . n 
B 1 262 GLU 262 228 228 GLU GLU B . n 
B 1 263 ASN 263 229 229 ASN ASN B . n 
B 1 264 GLY 264 230 230 GLY GLY B . n 
B 1 265 LEU 265 231 231 LEU LEU B . n 
B 1 266 GLU 266 232 232 GLU GLU B . n 
B 1 267 TYR 267 233 233 TYR TYR B . n 
B 1 268 LEU 268 234 234 LEU LEU B . n 
B 1 269 GLY 269 235 235 GLY GLY B . n 
B 1 270 TYR 270 236 236 TYR TYR B . n 
B 1 271 PHE 271 237 237 PHE PHE B . n 
B 1 272 ASN 272 238 238 ASN ASN B . n 
B 1 273 GLY 273 239 239 GLY GLY B . n 
B 1 274 SER 274 240 240 SER SER B . n 
B 1 275 TYR 275 241 241 TYR TYR B . n 
B 1 276 LEU 276 242 242 LEU LEU B . n 
B 1 277 GLU 277 243 243 GLU GLU B . n 
B 1 278 GLY 278 244 244 GLY GLY B . n 
B 1 279 PHE 279 245 245 PHE PHE B . n 
B 1 280 ASP 280 246 246 ASP ASP B . n 
B 1 281 SER 281 247 247 SER SER B . n 
B 1 282 GLU 282 248 248 GLU GLU B . n 
B 1 283 ALA 283 249 249 ALA ALA B . n 
B 1 284 PHE 284 250 250 PHE PHE B . n 
B 1 285 GLY 285 251 251 GLY GLY B . n 
B 1 286 MET 286 252 252 MET MET B . n 
B 1 287 SER 287 253 253 SER SER B . n 
B 1 288 ASN 288 254 254 ASN ASN B . n 
B 1 289 ALA 289 255 255 ALA ALA B . n 
B 1 290 GLU 290 256 256 GLU GLU B . n 
B 1 291 TYR 291 257 257 TYR TYR B . n 
B 1 292 LEU 292 258 258 LEU LEU B . n 
B 1 293 VAL 293 259 259 VAL VAL B . n 
B 1 294 GLU 294 260 260 GLU GLU B . n 
B 1 295 GLY 295 261 261 GLY GLY B . n 
B 1 296 ILE 296 262 262 ILE ILE B . n 
B 1 297 GLU 297 263 263 GLU GLU B . n 
B 1 298 ALA 298 264 264 ALA ALA B . n 
B 1 299 THR 299 265 265 THR THR B . n 
B 1 300 GLN 300 266 266 GLN GLN B . n 
B 1 301 LYS 301 267 267 LYS LYS B . n 
B 1 302 ALA 302 268 268 ALA ALA B . n 
B 1 303 ALA 303 269 269 ALA ALA B . n 
B 1 304 GLN 304 270 270 GLN GLN B . n 
B 1 305 SER 305 271 271 SER SER B . n 
B 1 306 GLY 306 272 272 GLY GLY B . n 
B 1 307 LYS 307 273 273 LYS LYS B . n 
B 1 308 ILE 308 274 274 ILE ILE B . n 
B 1 309 ILE 309 275 275 ILE ILE B . n 
B 1 310 THR 310 276 276 THR THR B . n 
B 1 311 MET 311 277 277 MET MET B . n 
B 1 312 THR 312 278 278 THR THR B . n 
B 1 313 LEU 313 279 279 LEU LEU B . n 
B 1 314 GLY 314 280 280 GLY GLY B . n 
B 1 315 LEU 315 281 281 LEU LEU B . n 
B 1 316 GLY 316 282 282 GLY GLY B . n 
B 1 317 GLU 317 283 283 GLU GLU B . n 
B 1 318 ALA 318 284 284 ALA ALA B . n 
B 1 319 ILE 319 285 285 ILE ILE B . n 
B 1 320 ASP 320 286 286 ASP ASP B . n 
B 1 321 ASN 321 287 287 ASN ASN B . n 
B 1 322 ASN 322 288 288 ASN ASN B . n 
B 1 323 THR 323 289 289 THR THR B . n 
B 1 324 GLY 324 290 290 GLY GLY B . n 
B 1 325 ILE 325 291 291 ILE ILE B . n 
B 1 326 ASP 326 292 292 ASP ASP B . n 
B 1 327 ASP 327 293 293 ASP ASP B . n 
B 1 328 GLN 328 294 294 GLN GLN B . n 
B 1 329 ARG 329 295 295 ARG ARG B . n 
B 1 330 GLU 330 296 296 GLU GLU B . n 
B 1 331 ASP 331 297 297 ASP ASP B . n 
B 1 332 VAL 332 298 298 VAL VAL B . n 
B 1 333 ASP 333 299 299 ASP ASP B . n 
B 1 334 LEU 334 300 300 LEU LEU B . n 
B 1 335 ASN 335 301 301 ASN ASN B . n 
B 1 336 ASP 336 302 302 ASP ASP B . n 
B 1 337 GLU 337 303 303 GLU GLU B . n 
B 1 338 GLU 338 304 304 GLU GLU B . n 
B 1 339 LEU 339 305 305 LEU LEU B . n 
B 1 340 ASN 340 306 306 ASN ASN B . n 
B 1 341 LYS 341 307 307 LYS LYS B . n 
B 1 342 ARG 342 308 308 ARG ARG B . n 
B 1 343 VAL 343 309 309 VAL VAL B . n 
B 1 344 ASP 344 310 310 ASP ASP B . n 
B 1 345 TYR 345 311 311 TYR TYR B . n 
B 1 346 LEU 346 312 312 LEU LEU B . n 
B 1 347 LEU 347 313 313 LEU LEU B . n 
B 1 348 ALA 348 314 314 ALA ALA B . n 
B 1 349 ILE 349 315 315 ILE ILE B . n 
B 1 350 PHE 350 316 316 PHE PHE B . n 
B 1 351 LEU 351 317 317 LEU LEU B . n 
B 1 352 ILE 352 318 318 ILE ILE B . n 
B 1 353 CYS 353 319 319 CYS CYS B . n 
B 1 354 ALA 354 320 320 ALA ALA B . n 
B 1 355 GLU 355 321 321 GLU GLU B . n 
B 1 356 LYS 356 322 322 LYS LYS B . n 
B 1 357 TYR 357 323 323 TYR TYR B . n 
B 1 358 SER 358 324 324 SER SER B . n 
B 1 359 TYR 359 325 325 TYR TYR B . n 
B 1 360 VAL 360 326 326 VAL VAL B . n 
B 1 361 TYR 361 327 327 TYR TYR B . n 
B 1 362 LEU 362 328 328 LEU LEU B . n 
B 1 363 HIS 363 329 329 HIS HIS B . n 
B 1 364 ASP 364 330 330 ASP ASP B . n 
B 1 365 GLY 365 331 331 GLY GLY B . n 
B 1 366 TYR 366 332 332 TYR TYR B . n 
B 1 367 LEU 367 333 333 LEU LEU B . n 
B 1 368 ALA 368 334 334 ALA ALA B . n 
B 1 369 THR 369 335 335 THR THR B . n 
B 1 370 ASN 370 336 336 ASN ASN B . n 
B 1 371 SER 371 337 337 SER SER B . n 
B 1 372 ALA 372 338 338 ALA ALA B . n 
B 1 373 VAL 373 339 339 VAL VAL B . n 
B 1 374 TRP 374 340 340 TRP TRP B . n 
B 1 375 LEU 375 341 341 LEU LEU B . n 
B 1 376 HIS 376 342 342 HIS HIS B . n 
B 1 377 GLN 377 343 343 GLN GLN B . n 
B 1 378 PHE 378 344 344 PHE PHE B . n 
B 1 379 ASP 379 345 345 ASP ASP B . n 
B 1 380 GLN 380 346 346 GLN GLN B . n 
B 1 381 TYR 381 347 347 TYR TYR B . n 
B 1 382 LYS 382 348 348 LYS LYS B . n 
B 1 383 LYS 383 349 349 LYS LYS B . n 
B 1 384 ALA 384 350 350 ALA ALA B . n 
B 1 385 LEU 385 351 351 LEU LEU B . n 
B 1 386 GLY 386 352 352 GLY GLY B . n 
B 1 387 ALA 387 353 353 ALA ALA B . n 
B 1 388 PRO 388 354 354 PRO PRO B . n 
B 1 389 LEU 389 355 355 LEU LEU B . n 
B 1 390 GLY 390 356 356 GLY GLY B . n 
B 1 391 LYS 391 357 357 LYS LYS B . n 
B 1 392 ALA 392 358 358 ALA ALA B . n 
B 1 393 ILE 393 359 359 ILE ILE B . n 
B 1 394 LYS 394 360 360 LYS LYS B . n 
B 1 395 ASN 395 361 361 ASN ASN B . n 
B 1 396 GLY 396 362 362 GLY GLY B . n 
B 1 397 TYR 397 363 363 TYR TYR B . n 
B 1 398 ILE 398 364 364 ILE ILE B . n 
B 1 399 TYR 399 365 365 TYR TYR B . n 
B 1 400 THR 400 366 366 THR THR B . n 
B 1 401 ARG 401 367 367 ARG ARG B . n 
B 1 402 LYS 402 368 368 LYS LYS B . n 
B 1 403 PHE 403 369 369 PHE PHE B . n 
B 1 404 GLU 404 370 370 GLU GLU B . n 
B 1 405 ASN 405 371 371 ASN ASN B . n 
B 1 406 LEU 406 372 372 LEU LEU B . n 
B 1 407 ASP 407 373 373 ASP ASP B . n 
B 1 408 VAL 408 374 374 VAL VAL B . n 
B 1 409 TRP 409 375 375 TRP TRP B . n 
B 1 410 LEU 410 376 376 LEU LEU B . n 
B 1 411 ASN 411 377 377 ASN ASN B . n 
B 1 412 LEU 412 378 378 LEU LEU B . n 
B 1 413 GLU 413 379 379 GLU GLU B . n 
B 1 414 THR 414 380 380 THR THR B . n 
B 1 415 GLN 415 381 381 GLN GLN B . n 
B 1 416 THR 416 382 382 THR THR B . n 
B 1 417 ALA 417 383 383 ALA ALA B . n 
B 1 418 THR 418 384 384 THR THR B . n 
B 1 419 LEU 419 385 385 LEU LEU B . n 
B 1 420 THR 420 386 386 THR THR B . n 
B 1 421 TRP 421 387 387 TRP TRP B . n 
B 1 422 LYS 422 388 388 LYS LYS B . n 
B 1 423 GLU 423 389 ?   ?   ?   B . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 2 X6Y 1 D X6Y 1 D 168 401 n 
C 2 X2Y 2 D X2Y 2 D 168 401 n 
C 2 FUC 3 D FUC 3 D 168 401 n 
C 2 X6Y 4 D X6Y 4 D 168 401 n 
D 2 X6Y 1 C X6Y 1 D 168 402 n 
D 2 X2Y 2 C X2Y 2 D 168 402 n 
D 2 FUC 3 C FUC 3 D 168 402 n 
D 2 X6Y 4 C X6Y 4 D 168 402 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 FUC ? ? FUC ? ? 'SUBJECT OF INVESTIGATION' ? 
2 X6Y ? ? X6Y ? ? 'SUBJECT OF INVESTIGATION' ? 
3 X2Y ? ? X2Y ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 HOH 1   401  1423 HOH HOH A . 
E 3 HOH 2   402  1041 HOH HOH A . 
E 3 HOH 3   403  1173 HOH HOH A . 
E 3 HOH 4   404  1159 HOH HOH A . 
E 3 HOH 5   405  1394 HOH HOH A . 
E 3 HOH 6   406  1377 HOH HOH A . 
E 3 HOH 7   407  1365 HOH HOH A . 
E 3 HOH 8   408  1332 HOH HOH A . 
E 3 HOH 9   409  1069 HOH HOH A . 
E 3 HOH 10  410  998  HOH HOH A . 
E 3 HOH 11  411  765  HOH HOH A . 
E 3 HOH 12  412  1004 HOH HOH A . 
E 3 HOH 13  413  677  HOH HOH A . 
E 3 HOH 14  414  1283 HOH HOH A . 
E 3 HOH 15  415  1400 HOH HOH A . 
E 3 HOH 16  416  625  HOH HOH A . 
E 3 HOH 17  417  1255 HOH HOH A . 
E 3 HOH 18  418  928  HOH HOH A . 
E 3 HOH 19  419  536  HOH HOH A . 
E 3 HOH 20  420  1162 HOH HOH A . 
E 3 HOH 21  421  1349 HOH HOH A . 
E 3 HOH 22  422  1179 HOH HOH A . 
E 3 HOH 23  423  684  HOH HOH A . 
E 3 HOH 24  424  1080 HOH HOH A . 
E 3 HOH 25  425  880  HOH HOH A . 
E 3 HOH 26  426  1469 HOH HOH A . 
E 3 HOH 27  427  980  HOH HOH A . 
E 3 HOH 28  428  1340 HOH HOH A . 
E 3 HOH 29  429  442  HOH HOH A . 
E 3 HOH 30  430  206  HOH HOH A . 
E 3 HOH 31  431  694  HOH HOH A . 
E 3 HOH 32  432  565  HOH HOH A . 
E 3 HOH 33  433  410  HOH HOH A . 
E 3 HOH 34  434  1265 HOH HOH A . 
E 3 HOH 35  435  798  HOH HOH A . 
E 3 HOH 36  436  1254 HOH HOH A . 
E 3 HOH 37  437  898  HOH HOH A . 
E 3 HOH 38  438  1457 HOH HOH A . 
E 3 HOH 39  439  428  HOH HOH A . 
E 3 HOH 40  440  962  HOH HOH A . 
E 3 HOH 41  441  1214 HOH HOH A . 
E 3 HOH 42  442  1076 HOH HOH A . 
E 3 HOH 43  443  1277 HOH HOH A . 
E 3 HOH 44  444  681  HOH HOH A . 
E 3 HOH 45  445  541  HOH HOH A . 
E 3 HOH 46  446  847  HOH HOH A . 
E 3 HOH 47  447  473  HOH HOH A . 
E 3 HOH 48  448  971  HOH HOH A . 
E 3 HOH 49  449  1023 HOH HOH A . 
E 3 HOH 50  450  208  HOH HOH A . 
E 3 HOH 51  451  645  HOH HOH A . 
E 3 HOH 52  452  1037 HOH HOH A . 
E 3 HOH 53  453  479  HOH HOH A . 
E 3 HOH 54  454  550  HOH HOH A . 
E 3 HOH 55  455  1389 HOH HOH A . 
E 3 HOH 56  456  9    HOH HOH A . 
E 3 HOH 57  457  125  HOH HOH A . 
E 3 HOH 58  458  1378 HOH HOH A . 
E 3 HOH 59  459  1328 HOH HOH A . 
E 3 HOH 60  460  1291 HOH HOH A . 
E 3 HOH 61  461  1148 HOH HOH A . 
E 3 HOH 62  462  499  HOH HOH A . 
E 3 HOH 63  463  164  HOH HOH A . 
E 3 HOH 64  464  823  HOH HOH A . 
E 3 HOH 65  465  1142 HOH HOH A . 
E 3 HOH 66  466  575  HOH HOH A . 
E 3 HOH 67  467  4    HOH HOH A . 
E 3 HOH 68  468  186  HOH HOH A . 
E 3 HOH 69  469  584  HOH HOH A . 
E 3 HOH 70  470  936  HOH HOH A . 
E 3 HOH 71  471  45   HOH HOH A . 
E 3 HOH 72  472  567  HOH HOH A . 
E 3 HOH 73  473  504  HOH HOH A . 
E 3 HOH 74  474  38   HOH HOH A . 
E 3 HOH 75  475  190  HOH HOH A . 
E 3 HOH 76  476  491  HOH HOH A . 
E 3 HOH 77  477  271  HOH HOH A . 
E 3 HOH 78  478  696  HOH HOH A . 
E 3 HOH 79  479  899  HOH HOH A . 
E 3 HOH 80  480  80   HOH HOH A . 
E 3 HOH 81  481  140  HOH HOH A . 
E 3 HOH 82  482  553  HOH HOH A . 
E 3 HOH 83  483  398  HOH HOH A . 
E 3 HOH 84  484  1042 HOH HOH A . 
E 3 HOH 85  485  1458 HOH HOH A . 
E 3 HOH 86  486  89   HOH HOH A . 
E 3 HOH 87  487  1026 HOH HOH A . 
E 3 HOH 88  488  1409 HOH HOH A . 
E 3 HOH 89  489  167  HOH HOH A . 
E 3 HOH 90  490  289  HOH HOH A . 
E 3 HOH 91  491  231  HOH HOH A . 
E 3 HOH 92  492  143  HOH HOH A . 
E 3 HOH 93  493  489  HOH HOH A . 
E 3 HOH 94  494  774  HOH HOH A . 
E 3 HOH 95  495  415  HOH HOH A . 
E 3 HOH 96  496  1275 HOH HOH A . 
E 3 HOH 97  497  582  HOH HOH A . 
E 3 HOH 98  498  78   HOH HOH A . 
E 3 HOH 99  499  276  HOH HOH A . 
E 3 HOH 100 500  126  HOH HOH A . 
E 3 HOH 101 501  561  HOH HOH A . 
E 3 HOH 102 502  145  HOH HOH A . 
E 3 HOH 103 503  388  HOH HOH A . 
E 3 HOH 104 504  554  HOH HOH A . 
E 3 HOH 105 505  809  HOH HOH A . 
E 3 HOH 106 506  5    HOH HOH A . 
E 3 HOH 107 507  370  HOH HOH A . 
E 3 HOH 108 508  628  HOH HOH A . 
E 3 HOH 109 509  770  HOH HOH A . 
E 3 HOH 110 510  1195 HOH HOH A . 
E 3 HOH 111 511  43   HOH HOH A . 
E 3 HOH 112 512  230  HOH HOH A . 
E 3 HOH 113 513  474  HOH HOH A . 
E 3 HOH 114 514  87   HOH HOH A . 
E 3 HOH 115 515  969  HOH HOH A . 
E 3 HOH 116 516  935  HOH HOH A . 
E 3 HOH 117 517  1194 HOH HOH A . 
E 3 HOH 118 518  365  HOH HOH A . 
E 3 HOH 119 519  1118 HOH HOH A . 
E 3 HOH 120 520  244  HOH HOH A . 
E 3 HOH 121 521  327  HOH HOH A . 
E 3 HOH 122 522  26   HOH HOH A . 
E 3 HOH 123 523  1098 HOH HOH A . 
E 3 HOH 124 524  105  HOH HOH A . 
E 3 HOH 125 525  30   HOH HOH A . 
E 3 HOH 126 526  1251 HOH HOH A . 
E 3 HOH 127 527  212  HOH HOH A . 
E 3 HOH 128 528  418  HOH HOH A . 
E 3 HOH 129 529  513  HOH HOH A . 
E 3 HOH 130 530  545  HOH HOH A . 
E 3 HOH 131 531  728  HOH HOH A . 
E 3 HOH 132 532  17   HOH HOH A . 
E 3 HOH 133 533  432  HOH HOH A . 
E 3 HOH 134 534  407  HOH HOH A . 
E 3 HOH 135 535  1236 HOH HOH A . 
E 3 HOH 136 536  94   HOH HOH A . 
E 3 HOH 137 537  1121 HOH HOH A . 
E 3 HOH 138 538  23   HOH HOH A . 
E 3 HOH 139 539  95   HOH HOH A . 
E 3 HOH 140 540  909  HOH HOH A . 
E 3 HOH 141 541  293  HOH HOH A . 
E 3 HOH 142 542  305  HOH HOH A . 
E 3 HOH 143 543  253  HOH HOH A . 
E 3 HOH 144 544  1108 HOH HOH A . 
E 3 HOH 145 545  1045 HOH HOH A . 
E 3 HOH 146 546  183  HOH HOH A . 
E 3 HOH 147 547  82   HOH HOH A . 
E 3 HOH 148 548  153  HOH HOH A . 
E 3 HOH 149 549  805  HOH HOH A . 
E 3 HOH 150 550  166  HOH HOH A . 
E 3 HOH 151 551  178  HOH HOH A . 
E 3 HOH 152 552  661  HOH HOH A . 
E 3 HOH 153 553  120  HOH HOH A . 
E 3 HOH 154 554  224  HOH HOH A . 
E 3 HOH 155 555  1189 HOH HOH A . 
E 3 HOH 156 556  937  HOH HOH A . 
E 3 HOH 157 557  55   HOH HOH A . 
E 3 HOH 158 558  24   HOH HOH A . 
E 3 HOH 159 559  179  HOH HOH A . 
E 3 HOH 160 560  546  HOH HOH A . 
E 3 HOH 161 561  1454 HOH HOH A . 
E 3 HOH 162 562  991  HOH HOH A . 
E 3 HOH 163 563  614  HOH HOH A . 
E 3 HOH 164 564  6    HOH HOH A . 
E 3 HOH 165 565  599  HOH HOH A . 
E 3 HOH 166 566  287  HOH HOH A . 
E 3 HOH 167 567  1404 HOH HOH A . 
E 3 HOH 168 568  81   HOH HOH A . 
E 3 HOH 169 569  528  HOH HOH A . 
E 3 HOH 170 570  1329 HOH HOH A . 
E 3 HOH 171 571  73   HOH HOH A . 
E 3 HOH 172 572  47   HOH HOH A . 
E 3 HOH 173 573  18   HOH HOH A . 
E 3 HOH 174 574  315  HOH HOH A . 
E 3 HOH 175 575  1073 HOH HOH A . 
E 3 HOH 176 576  425  HOH HOH A . 
E 3 HOH 177 577  146  HOH HOH A . 
E 3 HOH 178 578  1216 HOH HOH A . 
E 3 HOH 179 579  369  HOH HOH A . 
E 3 HOH 180 580  400  HOH HOH A . 
E 3 HOH 181 581  848  HOH HOH A . 
E 3 HOH 182 582  815  HOH HOH A . 
E 3 HOH 183 583  366  HOH HOH A . 
E 3 HOH 184 584  216  HOH HOH A . 
E 3 HOH 185 585  269  HOH HOH A . 
E 3 HOH 186 586  705  HOH HOH A . 
E 3 HOH 187 587  416  HOH HOH A . 
E 3 HOH 188 588  132  HOH HOH A . 
E 3 HOH 189 589  842  HOH HOH A . 
E 3 HOH 190 590  833  HOH HOH A . 
E 3 HOH 191 591  66   HOH HOH A . 
E 3 HOH 192 592  894  HOH HOH A . 
E 3 HOH 193 593  199  HOH HOH A . 
E 3 HOH 194 594  70   HOH HOH A . 
E 3 HOH 195 595  551  HOH HOH A . 
E 3 HOH 196 596  534  HOH HOH A . 
E 3 HOH 197 597  1380 HOH HOH A . 
E 3 HOH 198 598  589  HOH HOH A . 
E 3 HOH 199 599  687  HOH HOH A . 
E 3 HOH 200 600  1049 HOH HOH A . 
E 3 HOH 201 601  71   HOH HOH A . 
E 3 HOH 202 602  123  HOH HOH A . 
E 3 HOH 203 603  48   HOH HOH A . 
E 3 HOH 204 604  1021 HOH HOH A . 
E 3 HOH 205 605  11   HOH HOH A . 
E 3 HOH 206 606  738  HOH HOH A . 
E 3 HOH 207 607  34   HOH HOH A . 
E 3 HOH 208 608  290  HOH HOH A . 
E 3 HOH 209 609  1145 HOH HOH A . 
E 3 HOH 210 610  211  HOH HOH A . 
E 3 HOH 211 611  485  HOH HOH A . 
E 3 HOH 212 612  1455 HOH HOH A . 
E 3 HOH 213 613  467  HOH HOH A . 
E 3 HOH 214 614  177  HOH HOH A . 
E 3 HOH 215 615  135  HOH HOH A . 
E 3 HOH 216 616  514  HOH HOH A . 
E 3 HOH 217 617  239  HOH HOH A . 
E 3 HOH 218 618  444  HOH HOH A . 
E 3 HOH 219 619  64   HOH HOH A . 
E 3 HOH 220 620  189  HOH HOH A . 
E 3 HOH 221 621  88   HOH HOH A . 
E 3 HOH 222 622  591  HOH HOH A . 
E 3 HOH 223 623  322  HOH HOH A . 
E 3 HOH 224 624  217  HOH HOH A . 
E 3 HOH 225 625  67   HOH HOH A . 
E 3 HOH 226 626  1385 HOH HOH A . 
E 3 HOH 227 627  77   HOH HOH A . 
E 3 HOH 228 628  53   HOH HOH A . 
E 3 HOH 229 629  878  HOH HOH A . 
E 3 HOH 230 630  1104 HOH HOH A . 
E 3 HOH 231 631  619  HOH HOH A . 
E 3 HOH 232 632  147  HOH HOH A . 
E 3 HOH 233 633  2    HOH HOH A . 
E 3 HOH 234 634  312  HOH HOH A . 
E 3 HOH 235 635  292  HOH HOH A . 
E 3 HOH 236 636  883  HOH HOH A . 
E 3 HOH 237 637  634  HOH HOH A . 
E 3 HOH 238 638  234  HOH HOH A . 
E 3 HOH 239 639  958  HOH HOH A . 
E 3 HOH 240 640  110  HOH HOH A . 
E 3 HOH 241 641  204  HOH HOH A . 
E 3 HOH 242 642  1399 HOH HOH A . 
E 3 HOH 243 643  335  HOH HOH A . 
E 3 HOH 244 644  1366 HOH HOH A . 
E 3 HOH 245 645  181  HOH HOH A . 
E 3 HOH 246 646  122  HOH HOH A . 
E 3 HOH 247 647  1375 HOH HOH A . 
E 3 HOH 248 648  440  HOH HOH A . 
E 3 HOH 249 649  160  HOH HOH A . 
E 3 HOH 250 650  182  HOH HOH A . 
E 3 HOH 251 651  1149 HOH HOH A . 
E 3 HOH 252 652  616  HOH HOH A . 
E 3 HOH 253 653  531  HOH HOH A . 
E 3 HOH 254 654  788  HOH HOH A . 
E 3 HOH 255 655  587  HOH HOH A . 
E 3 HOH 256 656  386  HOH HOH A . 
E 3 HOH 257 657  814  HOH HOH A . 
E 3 HOH 258 658  1402 HOH HOH A . 
E 3 HOH 259 659  503  HOH HOH A . 
E 3 HOH 260 660  97   HOH HOH A . 
E 3 HOH 261 661  341  HOH HOH A . 
E 3 HOH 262 662  313  HOH HOH A . 
E 3 HOH 263 663  350  HOH HOH A . 
E 3 HOH 264 664  813  HOH HOH A . 
E 3 HOH 265 665  1304 HOH HOH A . 
E 3 HOH 266 666  195  HOH HOH A . 
E 3 HOH 267 667  301  HOH HOH A . 
E 3 HOH 268 668  63   HOH HOH A . 
E 3 HOH 269 669  1168 HOH HOH A . 
E 3 HOH 270 670  20   HOH HOH A . 
E 3 HOH 271 671  257  HOH HOH A . 
E 3 HOH 272 672  879  HOH HOH A . 
E 3 HOH 273 673  1431 HOH HOH A . 
E 3 HOH 274 674  1197 HOH HOH A . 
E 3 HOH 275 675  10   HOH HOH A . 
E 3 HOH 276 676  247  HOH HOH A . 
E 3 HOH 277 677  27   HOH HOH A . 
E 3 HOH 278 678  29   HOH HOH A . 
E 3 HOH 279 679  1217 HOH HOH A . 
E 3 HOH 280 680  1352 HOH HOH A . 
E 3 HOH 281 681  328  HOH HOH A . 
E 3 HOH 282 682  296  HOH HOH A . 
E 3 HOH 283 683  812  HOH HOH A . 
E 3 HOH 284 684  1266 HOH HOH A . 
E 3 HOH 285 685  137  HOH HOH A . 
E 3 HOH 286 686  417  HOH HOH A . 
E 3 HOH 287 687  507  HOH HOH A . 
E 3 HOH 288 688  106  HOH HOH A . 
E 3 HOH 289 689  1138 HOH HOH A . 
E 3 HOH 290 690  1405 HOH HOH A . 
E 3 HOH 291 691  949  HOH HOH A . 
E 3 HOH 292 692  309  HOH HOH A . 
E 3 HOH 293 693  1424 HOH HOH A . 
E 3 HOH 294 694  221  HOH HOH A . 
E 3 HOH 295 695  1351 HOH HOH A . 
E 3 HOH 296 696  496  HOH HOH A . 
E 3 HOH 297 697  1338 HOH HOH A . 
E 3 HOH 298 698  1271 HOH HOH A . 
E 3 HOH 299 699  466  HOH HOH A . 
E 3 HOH 300 700  249  HOH HOH A . 
E 3 HOH 301 701  35   HOH HOH A . 
E 3 HOH 302 702  325  HOH HOH A . 
E 3 HOH 303 703  394  HOH HOH A . 
E 3 HOH 304 704  119  HOH HOH A . 
E 3 HOH 305 705  380  HOH HOH A . 
E 3 HOH 306 706  754  HOH HOH A . 
E 3 HOH 307 707  492  HOH HOH A . 
E 3 HOH 308 708  945  HOH HOH A . 
E 3 HOH 309 709  92   HOH HOH A . 
E 3 HOH 310 710  636  HOH HOH A . 
E 3 HOH 311 711  477  HOH HOH A . 
E 3 HOH 312 712  162  HOH HOH A . 
E 3 HOH 313 713  762  HOH HOH A . 
E 3 HOH 314 714  1257 HOH HOH A . 
E 3 HOH 315 715  707  HOH HOH A . 
E 3 HOH 316 716  486  HOH HOH A . 
E 3 HOH 317 717  75   HOH HOH A . 
E 3 HOH 318 718  737  HOH HOH A . 
E 3 HOH 319 719  1170 HOH HOH A . 
E 3 HOH 320 720  233  HOH HOH A . 
E 3 HOH 321 721  1448 HOH HOH A . 
E 3 HOH 322 722  446  HOH HOH A . 
E 3 HOH 323 723  620  HOH HOH A . 
E 3 HOH 324 724  724  HOH HOH A . 
E 3 HOH 325 725  709  HOH HOH A . 
E 3 HOH 326 726  592  HOH HOH A . 
E 3 HOH 327 727  538  HOH HOH A . 
E 3 HOH 328 728  456  HOH HOH A . 
E 3 HOH 329 729  295  HOH HOH A . 
E 3 HOH 330 730  454  HOH HOH A . 
E 3 HOH 331 731  698  HOH HOH A . 
E 3 HOH 332 732  250  HOH HOH A . 
E 3 HOH 333 733  563  HOH HOH A . 
E 3 HOH 334 734  663  HOH HOH A . 
E 3 HOH 335 735  516  HOH HOH A . 
E 3 HOH 336 736  630  HOH HOH A . 
E 3 HOH 337 737  918  HOH HOH A . 
E 3 HOH 338 738  1464 HOH HOH A . 
E 3 HOH 339 739  495  HOH HOH A . 
E 3 HOH 340 740  1084 HOH HOH A . 
E 3 HOH 341 741  1302 HOH HOH A . 
E 3 HOH 342 742  1077 HOH HOH A . 
E 3 HOH 343 743  1057 HOH HOH A . 
E 3 HOH 344 744  60   HOH HOH A . 
E 3 HOH 345 745  460  HOH HOH A . 
E 3 HOH 346 746  1020 HOH HOH A . 
E 3 HOH 347 747  1081 HOH HOH A . 
E 3 HOH 348 748  124  HOH HOH A . 
E 3 HOH 349 749  1047 HOH HOH A . 
E 3 HOH 350 750  427  HOH HOH A . 
E 3 HOH 351 751  912  HOH HOH A . 
E 3 HOH 352 752  1267 HOH HOH A . 
E 3 HOH 353 753  856  HOH HOH A . 
E 3 HOH 354 754  482  HOH HOH A . 
E 3 HOH 355 755  530  HOH HOH A . 
E 3 HOH 356 756  1001 HOH HOH A . 
E 3 HOH 357 757  1030 HOH HOH A . 
E 3 HOH 358 758  699  HOH HOH A . 
E 3 HOH 359 759  291  HOH HOH A . 
E 3 HOH 360 760  838  HOH HOH A . 
E 3 HOH 361 761  951  HOH HOH A . 
E 3 HOH 362 762  459  HOH HOH A . 
E 3 HOH 363 763  69   HOH HOH A . 
E 3 HOH 364 764  660  HOH HOH A . 
E 3 HOH 365 765  1294 HOH HOH A . 
E 3 HOH 366 766  270  HOH HOH A . 
E 3 HOH 367 767  481  HOH HOH A . 
E 3 HOH 368 768  226  HOH HOH A . 
E 3 HOH 369 769  65   HOH HOH A . 
E 3 HOH 370 770  741  HOH HOH A . 
E 3 HOH 371 771  1376 HOH HOH A . 
E 3 HOH 372 772  1272 HOH HOH A . 
E 3 HOH 373 773  368  HOH HOH A . 
E 3 HOH 374 774  573  HOH HOH A . 
E 3 HOH 375 775  1417 HOH HOH A . 
E 3 HOH 376 776  983  HOH HOH A . 
E 3 HOH 377 777  649  HOH HOH A . 
E 3 HOH 378 778  931  HOH HOH A . 
E 3 HOH 379 779  1382 HOH HOH A . 
E 3 HOH 380 780  1339 HOH HOH A . 
E 3 HOH 381 781  308  HOH HOH A . 
E 3 HOH 382 782  170  HOH HOH A . 
E 3 HOH 383 783  866  HOH HOH A . 
E 3 HOH 384 784  83   HOH HOH A . 
E 3 HOH 385 785  817  HOH HOH A . 
E 3 HOH 386 786  753  HOH HOH A . 
E 3 HOH 387 787  761  HOH HOH A . 
E 3 HOH 388 788  1357 HOH HOH A . 
E 3 HOH 389 789  356  HOH HOH A . 
E 3 HOH 390 790  607  HOH HOH A . 
E 3 HOH 391 791  311  HOH HOH A . 
E 3 HOH 392 792  74   HOH HOH A . 
E 3 HOH 393 793  668  HOH HOH A . 
E 3 HOH 394 794  757  HOH HOH A . 
E 3 HOH 395 795  1186 HOH HOH A . 
E 3 HOH 396 796  229  HOH HOH A . 
E 3 HOH 397 797  758  HOH HOH A . 
E 3 HOH 398 798  1322 HOH HOH A . 
E 3 HOH 399 799  1135 HOH HOH A . 
E 3 HOH 400 800  452  HOH HOH A . 
E 3 HOH 401 801  791  HOH HOH A . 
E 3 HOH 402 802  953  HOH HOH A . 
E 3 HOH 403 803  1230 HOH HOH A . 
E 3 HOH 404 804  302  HOH HOH A . 
E 3 HOH 405 805  248  HOH HOH A . 
E 3 HOH 406 806  571  HOH HOH A . 
E 3 HOH 407 807  601  HOH HOH A . 
E 3 HOH 408 808  1102 HOH HOH A . 
E 3 HOH 409 809  555  HOH HOH A . 
E 3 HOH 410 810  232  HOH HOH A . 
E 3 HOH 411 811  1372 HOH HOH A . 
E 3 HOH 412 812  68   HOH HOH A . 
E 3 HOH 413 813  458  HOH HOH A . 
E 3 HOH 414 814  193  HOH HOH A . 
E 3 HOH 415 815  52   HOH HOH A . 
E 3 HOH 416 816  919  HOH HOH A . 
E 3 HOH 417 817  1316 HOH HOH A . 
E 3 HOH 418 818  1056 HOH HOH A . 
E 3 HOH 419 819  760  HOH HOH A . 
E 3 HOH 420 820  1201 HOH HOH A . 
E 3 HOH 421 821  1140 HOH HOH A . 
E 3 HOH 422 822  822  HOH HOH A . 
E 3 HOH 423 823  882  HOH HOH A . 
E 3 HOH 424 824  1443 HOH HOH A . 
E 3 HOH 425 825  653  HOH HOH A . 
E 3 HOH 426 826  633  HOH HOH A . 
E 3 HOH 427 827  1359 HOH HOH A . 
E 3 HOH 428 828  1111 HOH HOH A . 
E 3 HOH 429 829  992  HOH HOH A . 
E 3 HOH 430 830  1334 HOH HOH A . 
E 3 HOH 431 831  733  HOH HOH A . 
E 3 HOH 432 832  861  HOH HOH A . 
E 3 HOH 433 833  1299 HOH HOH A . 
E 3 HOH 434 834  174  HOH HOH A . 
E 3 HOH 435 835  1247 HOH HOH A . 
E 3 HOH 436 836  1362 HOH HOH A . 
E 3 HOH 437 837  1132 HOH HOH A . 
E 3 HOH 438 838  875  HOH HOH A . 
E 3 HOH 439 839  237  HOH HOH A . 
E 3 HOH 440 840  539  HOH HOH A . 
E 3 HOH 441 841  605  HOH HOH A . 
E 3 HOH 442 842  1094 HOH HOH A . 
E 3 HOH 443 843  796  HOH HOH A . 
E 3 HOH 444 844  393  HOH HOH A . 
E 3 HOH 445 845  430  HOH HOH A . 
E 3 HOH 446 846  967  HOH HOH A . 
E 3 HOH 447 847  821  HOH HOH A . 
E 3 HOH 448 848  723  HOH HOH A . 
E 3 HOH 449 849  905  HOH HOH A . 
E 3 HOH 450 850  1373 HOH HOH A . 
E 3 HOH 451 851  1447 HOH HOH A . 
E 3 HOH 452 852  163  HOH HOH A . 
E 3 HOH 453 853  874  HOH HOH A . 
E 3 HOH 454 854  1090 HOH HOH A . 
E 3 HOH 455 855  1456 HOH HOH A . 
E 3 HOH 456 856  825  HOH HOH A . 
E 3 HOH 457 857  1379 HOH HOH A . 
E 3 HOH 458 858  429  HOH HOH A . 
E 3 HOH 459 859  1244 HOH HOH A . 
E 3 HOH 460 860  1074 HOH HOH A . 
E 3 HOH 461 861  1288 HOH HOH A . 
E 3 HOH 462 862  819  HOH HOH A . 
E 3 HOH 463 863  581  HOH HOH A . 
E 3 HOH 464 864  1387 HOH HOH A . 
E 3 HOH 465 865  1335 HOH HOH A . 
E 3 HOH 466 866  1426 HOH HOH A . 
E 3 HOH 467 867  463  HOH HOH A . 
E 3 HOH 468 868  1241 HOH HOH A . 
E 3 HOH 469 869  294  HOH HOH A . 
E 3 HOH 470 870  1442 HOH HOH A . 
E 3 HOH 471 871  1078 HOH HOH A . 
E 3 HOH 472 872  631  HOH HOH A . 
E 3 HOH 473 873  775  HOH HOH A . 
E 3 HOH 474 874  1311 HOH HOH A . 
E 3 HOH 475 875  461  HOH HOH A . 
E 3 HOH 476 876  888  HOH HOH A . 
E 3 HOH 477 877  730  HOH HOH A . 
E 3 HOH 478 878  1374 HOH HOH A . 
E 3 HOH 479 879  1297 HOH HOH A . 
E 3 HOH 480 880  535  HOH HOH A . 
E 3 HOH 481 881  978  HOH HOH A . 
E 3 HOH 482 882  572  HOH HOH A . 
E 3 HOH 483 883  98   HOH HOH A . 
E 3 HOH 484 884  598  HOH HOH A . 
E 3 HOH 485 885  1066 HOH HOH A . 
E 3 HOH 486 886  387  HOH HOH A . 
E 3 HOH 487 887  1024 HOH HOH A . 
E 3 HOH 488 888  600  HOH HOH A . 
E 3 HOH 489 889  1427 HOH HOH A . 
E 3 HOH 490 890  169  HOH HOH A . 
E 3 HOH 491 891  1256 HOH HOH A . 
E 3 HOH 492 892  434  HOH HOH A . 
E 3 HOH 493 893  220  HOH HOH A . 
E 3 HOH 494 894  776  HOH HOH A . 
E 3 HOH 495 895  1428 HOH HOH A . 
E 3 HOH 496 896  651  HOH HOH A . 
E 3 HOH 497 897  543  HOH HOH A . 
E 3 HOH 498 898  964  HOH HOH A . 
E 3 HOH 499 899  844  HOH HOH A . 
E 3 HOH 500 900  510  HOH HOH A . 
E 3 HOH 501 901  845  HOH HOH A . 
E 3 HOH 502 902  1124 HOH HOH A . 
E 3 HOH 503 903  624  HOH HOH A . 
E 3 HOH 504 904  1013 HOH HOH A . 
E 3 HOH 505 905  579  HOH HOH A . 
E 3 HOH 506 906  1209 HOH HOH A . 
E 3 HOH 507 907  973  HOH HOH A . 
E 3 HOH 508 908  652  HOH HOH A . 
E 3 HOH 509 909  1054 HOH HOH A . 
E 3 HOH 510 910  618  HOH HOH A . 
E 3 HOH 511 911  1211 HOH HOH A . 
E 3 HOH 512 912  438  HOH HOH A . 
E 3 HOH 513 913  1075 HOH HOH A . 
E 3 HOH 514 914  1396 HOH HOH A . 
E 3 HOH 515 915  1468 HOH HOH A . 
E 3 HOH 516 916  1446 HOH HOH A . 
E 3 HOH 517 917  1330 HOH HOH A . 
E 3 HOH 518 918  843  HOH HOH A . 
E 3 HOH 519 919  782  HOH HOH A . 
E 3 HOH 520 920  736  HOH HOH A . 
E 3 HOH 521 921  1146 HOH HOH A . 
E 3 HOH 522 922  1063 HOH HOH A . 
E 3 HOH 523 923  236  HOH HOH A . 
E 3 HOH 524 924  156  HOH HOH A . 
E 3 HOH 525 925  1000 HOH HOH A . 
E 3 HOH 526 926  1009 HOH HOH A . 
E 3 HOH 527 927  1253 HOH HOH A . 
E 3 HOH 528 928  1449 HOH HOH A . 
E 3 HOH 529 929  319  HOH HOH A . 
E 3 HOH 530 930  648  HOH HOH A . 
E 3 HOH 531 931  1384 HOH HOH A . 
E 3 HOH 532 932  1238 HOH HOH A . 
E 3 HOH 533 933  1429 HOH HOH A . 
E 3 HOH 534 934  1259 HOH HOH A . 
E 3 HOH 535 935  522  HOH HOH A . 
E 3 HOH 536 936  324  HOH HOH A . 
E 3 HOH 537 937  1269 HOH HOH A . 
E 3 HOH 538 938  570  HOH HOH A . 
E 3 HOH 539 939  1324 HOH HOH A . 
E 3 HOH 540 940  114  HOH HOH A . 
E 3 HOH 541 941  1144 HOH HOH A . 
E 3 HOH 542 942  1126 HOH HOH A . 
E 3 HOH 543 943  972  HOH HOH A . 
E 3 HOH 544 944  1071 HOH HOH A . 
E 3 HOH 545 945  1343 HOH HOH A . 
E 3 HOH 546 946  840  HOH HOH A . 
E 3 HOH 547 947  280  HOH HOH A . 
E 3 HOH 548 948  855  HOH HOH A . 
E 3 HOH 549 949  1401 HOH HOH A . 
E 3 HOH 550 950  1019 HOH HOH A . 
E 3 HOH 551 951  794  HOH HOH A . 
E 3 HOH 552 952  243  HOH HOH A . 
E 3 HOH 553 953  585  HOH HOH A . 
E 3 HOH 554 954  889  HOH HOH A . 
E 3 HOH 555 955  557  HOH HOH A . 
E 3 HOH 556 956  207  HOH HOH A . 
E 3 HOH 557 957  1331 HOH HOH A . 
E 3 HOH 558 958  1092 HOH HOH A . 
E 3 HOH 559 959  704  HOH HOH A . 
E 3 HOH 560 960  318  HOH HOH A . 
E 3 HOH 561 961  769  HOH HOH A . 
E 3 HOH 562 962  493  HOH HOH A . 
E 3 HOH 563 963  101  HOH HOH A . 
E 3 HOH 564 964  885  HOH HOH A . 
E 3 HOH 565 965  1055 HOH HOH A . 
E 3 HOH 566 966  41   HOH HOH A . 
E 3 HOH 567 967  982  HOH HOH A . 
E 3 HOH 568 968  241  HOH HOH A . 
E 3 HOH 569 969  1237 HOH HOH A . 
E 3 HOH 570 970  537  HOH HOH A . 
E 3 HOH 571 971  1361 HOH HOH A . 
E 3 HOH 572 972  1184 HOH HOH A . 
E 3 HOH 573 973  219  HOH HOH A . 
E 3 HOH 574 974  1386 HOH HOH A . 
E 3 HOH 575 975  200  HOH HOH A . 
E 3 HOH 576 976  453  HOH HOH A . 
E 3 HOH 577 977  323  HOH HOH A . 
E 3 HOH 578 978  569  HOH HOH A . 
E 3 HOH 579 979  799  HOH HOH A . 
E 3 HOH 580 980  1101 HOH HOH A . 
E 3 HOH 581 981  1422 HOH HOH A . 
E 3 HOH 582 982  1413 HOH HOH A . 
E 3 HOH 583 983  373  HOH HOH A . 
E 3 HOH 584 984  1295 HOH HOH A . 
E 3 HOH 585 985  1388 HOH HOH A . 
E 3 HOH 586 986  509  HOH HOH A . 
E 3 HOH 587 987  594  HOH HOH A . 
E 3 HOH 588 988  755  HOH HOH A . 
E 3 HOH 589 989  526  HOH HOH A . 
E 3 HOH 590 990  1003 HOH HOH A . 
E 3 HOH 591 991  1123 HOH HOH A . 
E 3 HOH 592 992  606  HOH HOH A . 
E 3 HOH 593 993  562  HOH HOH A . 
E 3 HOH 594 994  751  HOH HOH A . 
E 3 HOH 595 995  621  HOH HOH A . 
E 3 HOH 596 996  727  HOH HOH A . 
E 3 HOH 597 997  424  HOH HOH A . 
E 3 HOH 598 998  333  HOH HOH A . 
E 3 HOH 599 999  993  HOH HOH A . 
E 3 HOH 600 1000 475  HOH HOH A . 
E 3 HOH 601 1001 789  HOH HOH A . 
E 3 HOH 602 1002 1465 HOH HOH A . 
E 3 HOH 603 1003 547  HOH HOH A . 
E 3 HOH 604 1004 1089 HOH HOH A . 
E 3 HOH 605 1005 1250 HOH HOH A . 
E 3 HOH 606 1006 801  HOH HOH A . 
E 3 HOH 607 1007 525  HOH HOH A . 
E 3 HOH 608 1008 1363 HOH HOH A . 
E 3 HOH 609 1009 942  HOH HOH A . 
E 3 HOH 610 1010 472  HOH HOH A . 
E 3 HOH 611 1011 1356 HOH HOH A . 
E 3 HOH 612 1012 497  HOH HOH A . 
E 3 HOH 613 1013 1151 HOH HOH A . 
E 3 HOH 614 1014 767  HOH HOH A . 
E 3 HOH 615 1015 864  HOH HOH A . 
E 3 HOH 616 1016 266  HOH HOH A . 
E 3 HOH 617 1017 1215 HOH HOH A . 
E 3 HOH 618 1018 268  HOH HOH A . 
E 3 HOH 619 1019 642  HOH HOH A . 
E 3 HOH 620 1020 1222 HOH HOH A . 
E 3 HOH 621 1021 1139 HOH HOH A . 
E 3 HOH 622 1022 490  HOH HOH A . 
E 3 HOH 623 1023 511  HOH HOH A . 
E 3 HOH 624 1024 1284 HOH HOH A . 
E 3 HOH 625 1025 1150 HOH HOH A . 
E 3 HOH 626 1026 981  HOH HOH A . 
E 3 HOH 627 1027 1062 HOH HOH A . 
E 3 HOH 628 1028 580  HOH HOH A . 
E 3 HOH 629 1029 1285 HOH HOH A . 
E 3 HOH 630 1030 656  HOH HOH A . 
E 3 HOH 631 1031 478  HOH HOH A . 
E 3 HOH 632 1032 901  HOH HOH A . 
E 3 HOH 633 1033 1293 HOH HOH A . 
E 3 HOH 634 1034 1190 HOH HOH A . 
E 3 HOH 635 1035 976  HOH HOH A . 
E 3 HOH 636 1036 865  HOH HOH A . 
E 3 HOH 637 1037 828  HOH HOH A . 
E 3 HOH 638 1038 834  HOH HOH A . 
E 3 HOH 639 1039 1182 HOH HOH A . 
E 3 HOH 640 1040 1233 HOH HOH A . 
E 3 HOH 641 1041 1034 HOH HOH A . 
E 3 HOH 642 1042 986  HOH HOH A . 
E 3 HOH 643 1043 1202 HOH HOH A . 
E 3 HOH 644 1044 667  HOH HOH A . 
E 3 HOH 645 1045 678  HOH HOH A . 
E 3 HOH 646 1046 852  HOH HOH A . 
E 3 HOH 647 1047 1342 HOH HOH A . 
E 3 HOH 648 1048 714  HOH HOH A . 
E 3 HOH 649 1049 688  HOH HOH A . 
E 3 HOH 650 1050 1174 HOH HOH A . 
E 3 HOH 651 1051 141  HOH HOH A . 
E 3 HOH 652 1052 944  HOH HOH A . 
E 3 HOH 653 1053 423  HOH HOH A . 
E 3 HOH 654 1054 1416 HOH HOH A . 
E 3 HOH 655 1055 1025 HOH HOH A . 
E 3 HOH 656 1056 902  HOH HOH A . 
E 3 HOH 657 1057 987  HOH HOH A . 
E 3 HOH 658 1058 334  HOH HOH A . 
E 3 HOH 659 1059 932  HOH HOH A . 
E 3 HOH 660 1060 781  HOH HOH A . 
E 3 HOH 661 1061 917  HOH HOH A . 
E 3 HOH 662 1062 1317 HOH HOH A . 
E 3 HOH 663 1063 420  HOH HOH A . 
E 3 HOH 664 1064 806  HOH HOH A . 
E 3 HOH 665 1065 568  HOH HOH A . 
E 3 HOH 666 1066 354  HOH HOH A . 
E 3 HOH 667 1067 1155 HOH HOH A . 
E 3 HOH 668 1068 924  HOH HOH A . 
E 3 HOH 669 1069 431  HOH HOH A . 
E 3 HOH 670 1070 871  HOH HOH A . 
E 3 HOH 671 1071 670  HOH HOH A . 
E 3 HOH 672 1072 378  HOH HOH A . 
E 3 HOH 673 1073 1007 HOH HOH A . 
E 3 HOH 674 1074 644  HOH HOH A . 
E 3 HOH 675 1075 1318 HOH HOH A . 
E 3 HOH 676 1076 533  HOH HOH A . 
E 3 HOH 677 1077 390  HOH HOH A . 
E 3 HOH 678 1078 597  HOH HOH A . 
E 3 HOH 679 1079 947  HOH HOH A . 
E 3 HOH 680 1080 336  HOH HOH A . 
E 3 HOH 681 1081 1206 HOH HOH A . 
E 3 HOH 682 1082 225  HOH HOH A . 
E 3 HOH 683 1083 1301 HOH HOH A . 
E 3 HOH 684 1084 99   HOH HOH A . 
E 3 HOH 685 1085 1278 HOH HOH A . 
E 3 HOH 686 1086 1440 HOH HOH A . 
E 3 HOH 687 1087 382  HOH HOH A . 
E 3 HOH 688 1088 766  HOH HOH A . 
E 3 HOH 689 1089 974  HOH HOH A . 
E 3 HOH 690 1090 984  HOH HOH A . 
E 3 HOH 691 1091 1406 HOH HOH A . 
E 3 HOH 692 1092 339  HOH HOH A . 
E 3 HOH 693 1093 1107 HOH HOH A . 
E 3 HOH 694 1094 1289 HOH HOH A . 
E 3 HOH 695 1095 1260 HOH HOH A . 
E 3 HOH 696 1096 1002 HOH HOH A . 
E 3 HOH 697 1097 501  HOH HOH A . 
E 3 HOH 698 1098 1100 HOH HOH A . 
E 3 HOH 699 1099 326  HOH HOH A . 
E 3 HOH 700 1100 90   HOH HOH A . 
E 3 HOH 701 1101 449  HOH HOH A . 
E 3 HOH 702 1102 985  HOH HOH A . 
E 3 HOH 703 1103 1419 HOH HOH A . 
E 3 HOH 704 1104 337  HOH HOH A . 
E 3 HOH 705 1105 1169 HOH HOH A . 
E 3 HOH 706 1106 1213 HOH HOH A . 
E 3 HOH 707 1107 1421 HOH HOH A . 
E 3 HOH 708 1108 391  HOH HOH A . 
E 3 HOH 709 1109 1129 HOH HOH A . 
E 3 HOH 710 1110 623  HOH HOH A . 
E 3 HOH 711 1111 719  HOH HOH A . 
E 3 HOH 712 1112 144  HOH HOH A . 
E 3 HOH 713 1113 1407 HOH HOH A . 
E 3 HOH 714 1114 604  HOH HOH A . 
E 3 HOH 715 1115 739  HOH HOH A . 
E 3 HOH 716 1116 929  HOH HOH A . 
E 3 HOH 717 1117 1088 HOH HOH A . 
E 3 HOH 718 1118 690  HOH HOH A . 
E 3 HOH 719 1119 1420 HOH HOH A . 
E 3 HOH 720 1120 804  HOH HOH A . 
E 3 HOH 721 1121 222  HOH HOH A . 
E 3 HOH 722 1122 1147 HOH HOH A . 
E 3 HOH 723 1123 934  HOH HOH A . 
E 3 HOH 724 1124 938  HOH HOH A . 
F 3 HOH 1   401  1203 HOH HOH B . 
F 3 HOH 2   402  1070 HOH HOH B . 
F 3 HOH 3   403  1274 HOH HOH B . 
F 3 HOH 4   404  1258 HOH HOH B . 
F 3 HOH 5   405  1450 HOH HOH B . 
F 3 HOH 6   406  655  HOH HOH B . 
F 3 HOH 7   407  886  HOH HOH B . 
F 3 HOH 8   408  1466 HOH HOH B . 
F 3 HOH 9   409  1163 HOH HOH B . 
F 3 HOH 10  410  1453 HOH HOH B . 
F 3 HOH 11  411  1153 HOH HOH B . 
F 3 HOH 12  412  1130 HOH HOH B . 
F 3 HOH 13  413  213  HOH HOH B . 
F 3 HOH 14  414  907  HOH HOH B . 
F 3 HOH 15  415  832  HOH HOH B . 
F 3 HOH 16  416  517  HOH HOH B . 
F 3 HOH 17  417  824  HOH HOH B . 
F 3 HOH 18  418  240  HOH HOH B . 
F 3 HOH 19  419  908  HOH HOH B . 
F 3 HOH 20  420  1060 HOH HOH B . 
F 3 HOH 21  421  419  HOH HOH B . 
F 3 HOH 22  422  277  HOH HOH B . 
F 3 HOH 23  423  406  HOH HOH B . 
F 3 HOH 24  424  816  HOH HOH B . 
F 3 HOH 25  425  785  HOH HOH B . 
F 3 HOH 26  426  1103 HOH HOH B . 
F 3 HOH 27  427  402  HOH HOH B . 
F 3 HOH 28  428  777  HOH HOH B . 
F 3 HOH 29  429  1205 HOH HOH B . 
F 3 HOH 30  430  970  HOH HOH B . 
F 3 HOH 31  431  952  HOH HOH B . 
F 3 HOH 32  432  869  HOH HOH B . 
F 3 HOH 33  433  1105 HOH HOH B . 
F 3 HOH 34  434  1191 HOH HOH B . 
F 3 HOH 35  435  1038 HOH HOH B . 
F 3 HOH 36  436  968  HOH HOH B . 
F 3 HOH 37  437  1249 HOH HOH B . 
F 3 HOH 38  438  960  HOH HOH B . 
F 3 HOH 39  439  1200 HOH HOH B . 
F 3 HOH 40  440  915  HOH HOH B . 
F 3 HOH 41  441  1029 HOH HOH B . 
F 3 HOH 42  442  1425 HOH HOH B . 
F 3 HOH 43  443  778  HOH HOH B . 
F 3 HOH 44  444  46   HOH HOH B . 
F 3 HOH 45  445  542  HOH HOH B . 
F 3 HOH 46  446  1122 HOH HOH B . 
F 3 HOH 47  447  8    HOH HOH B . 
F 3 HOH 48  448  948  HOH HOH B . 
F 3 HOH 49  449  1325 HOH HOH B . 
F 3 HOH 50  450  405  HOH HOH B . 
F 3 HOH 51  451  664  HOH HOH B . 
F 3 HOH 52  452  360  HOH HOH B . 
F 3 HOH 53  453  93   HOH HOH B . 
F 3 HOH 54  454  1412 HOH HOH B . 
F 3 HOH 55  455  128  HOH HOH B . 
F 3 HOH 56  456  759  HOH HOH B . 
F 3 HOH 57  457  408  HOH HOH B . 
F 3 HOH 58  458  1166 HOH HOH B . 
F 3 HOH 59  459  238  HOH HOH B . 
F 3 HOH 60  460  742  HOH HOH B . 
F 3 HOH 61  461  560  HOH HOH B . 
F 3 HOH 62  462  1452 HOH HOH B . 
F 3 HOH 63  463  1204 HOH HOH B . 
F 3 HOH 64  464  109  HOH HOH B . 
F 3 HOH 65  465  639  HOH HOH B . 
F 3 HOH 66  466  281  HOH HOH B . 
F 3 HOH 67  467  54   HOH HOH B . 
F 3 HOH 68  468  85   HOH HOH B . 
F 3 HOH 69  469  483  HOH HOH B . 
F 3 HOH 70  470  858  HOH HOH B . 
F 3 HOH 71  471  519  HOH HOH B . 
F 3 HOH 72  472  86   HOH HOH B . 
F 3 HOH 73  473  1134 HOH HOH B . 
F 3 HOH 74  474  772  HOH HOH B . 
F 3 HOH 75  475  310  HOH HOH B . 
F 3 HOH 76  476  414  HOH HOH B . 
F 3 HOH 77  477  502  HOH HOH B . 
F 3 HOH 78  478  282  HOH HOH B . 
F 3 HOH 79  479  1    HOH HOH B . 
F 3 HOH 80  480  149  HOH HOH B . 
F 3 HOH 81  481  395  HOH HOH B . 
F 3 HOH 82  482  455  HOH HOH B . 
F 3 HOH 83  483  107  HOH HOH B . 
F 3 HOH 84  484  344  HOH HOH B . 
F 3 HOH 85  485  807  HOH HOH B . 
F 3 HOH 86  486  111  HOH HOH B . 
F 3 HOH 87  487  304  HOH HOH B . 
F 3 HOH 88  488  192  HOH HOH B . 
F 3 HOH 89  489  352  HOH HOH B . 
F 3 HOH 90  490  1065 HOH HOH B . 
F 3 HOH 91  491  464  HOH HOH B . 
F 3 HOH 92  492  303  HOH HOH B . 
F 3 HOH 93  493  734  HOH HOH B . 
F 3 HOH 94  494  1393 HOH HOH B . 
F 3 HOH 95  495  1035 HOH HOH B . 
F 3 HOH 96  496  829  HOH HOH B . 
F 3 HOH 97  497  31   HOH HOH B . 
F 3 HOH 98  498  506  HOH HOH B . 
F 3 HOH 99  499  15   HOH HOH B . 
F 3 HOH 100 500  426  HOH HOH B . 
F 3 HOH 101 501  184  HOH HOH B . 
F 3 HOH 102 502  457  HOH HOH B . 
F 3 HOH 103 503  108  HOH HOH B . 
F 3 HOH 104 504  158  HOH HOH B . 
F 3 HOH 105 505  165  HOH HOH B . 
F 3 HOH 106 506  411  HOH HOH B . 
F 3 HOH 107 507  351  HOH HOH B . 
F 3 HOH 108 508  131  HOH HOH B . 
F 3 HOH 109 509  1128 HOH HOH B . 
F 3 HOH 110 510  404  HOH HOH B . 
F 3 HOH 111 511  647  HOH HOH B . 
F 3 HOH 112 512  702  HOH HOH B . 
F 3 HOH 113 513  995  HOH HOH B . 
F 3 HOH 114 514  521  HOH HOH B . 
F 3 HOH 115 515  13   HOH HOH B . 
F 3 HOH 116 516  210  HOH HOH B . 
F 3 HOH 117 517  332  HOH HOH B . 
F 3 HOH 118 518  142  HOH HOH B . 
F 3 HOH 119 519  926  HOH HOH B . 
F 3 HOH 120 520  196  HOH HOH B . 
F 3 HOH 121 521  672  HOH HOH B . 
F 3 HOH 122 522  396  HOH HOH B . 
F 3 HOH 123 523  203  HOH HOH B . 
F 3 HOH 124 524  665  HOH HOH B . 
F 3 HOH 125 525  37   HOH HOH B . 
F 3 HOH 126 526  152  HOH HOH B . 
F 3 HOH 127 527  1095 HOH HOH B . 
F 3 HOH 128 528  25   HOH HOH B . 
F 3 HOH 129 529  1064 HOH HOH B . 
F 3 HOH 130 530  155  HOH HOH B . 
F 3 HOH 131 531  133  HOH HOH B . 
F 3 HOH 132 532  549  HOH HOH B . 
F 3 HOH 133 533  413  HOH HOH B . 
F 3 HOH 134 534  330  HOH HOH B . 
F 3 HOH 135 535  1059 HOH HOH B . 
F 3 HOH 136 536  643  HOH HOH B . 
F 3 HOH 137 537  712  HOH HOH B . 
F 3 HOH 138 538  104  HOH HOH B . 
F 3 HOH 139 539  338  HOH HOH B . 
F 3 HOH 140 540  113  HOH HOH B . 
F 3 HOH 141 541  28   HOH HOH B . 
F 3 HOH 142 542  173  HOH HOH B . 
F 3 HOH 143 543  685  HOH HOH B . 
F 3 HOH 144 544  58   HOH HOH B . 
F 3 HOH 145 545  904  HOH HOH B . 
F 3 HOH 146 546  264  HOH HOH B . 
F 3 HOH 147 547  57   HOH HOH B . 
F 3 HOH 148 548  194  HOH HOH B . 
F 3 HOH 149 549  1131 HOH HOH B . 
F 3 HOH 150 550  700  HOH HOH B . 
F 3 HOH 151 551  910  HOH HOH B . 
F 3 HOH 152 552  1199 HOH HOH B . 
F 3 HOH 153 553  284  HOH HOH B . 
F 3 HOH 154 554  40   HOH HOH B . 
F 3 HOH 155 555  1354 HOH HOH B . 
F 3 HOH 156 556  197  HOH HOH B . 
F 3 HOH 157 557  259  HOH HOH B . 
F 3 HOH 158 558  577  HOH HOH B . 
F 3 HOH 159 559  227  HOH HOH B . 
F 3 HOH 160 560  138  HOH HOH B . 
F 3 HOH 161 561  779  HOH HOH B . 
F 3 HOH 162 562  91   HOH HOH B . 
F 3 HOH 163 563  518  HOH HOH B . 
F 3 HOH 164 564  7    HOH HOH B . 
F 3 HOH 165 565  622  HOH HOH B . 
F 3 HOH 166 566  564  HOH HOH B . 
F 3 HOH 167 567  14   HOH HOH B . 
F 3 HOH 168 568  51   HOH HOH B . 
F 3 HOH 169 569  744  HOH HOH B . 
F 3 HOH 170 570  159  HOH HOH B . 
F 3 HOH 171 571  50   HOH HOH B . 
F 3 HOH 172 572  1337 HOH HOH B . 
F 3 HOH 173 573  21   HOH HOH B . 
F 3 HOH 174 574  102  HOH HOH B . 
F 3 HOH 175 575  1245 HOH HOH B . 
F 3 HOH 176 576  468  HOH HOH B . 
F 3 HOH 177 577  157  HOH HOH B . 
F 3 HOH 178 578  532  HOH HOH B . 
F 3 HOH 179 579  540  HOH HOH B . 
F 3 HOH 180 580  201  HOH HOH B . 
F 3 HOH 181 581  44   HOH HOH B . 
F 3 HOH 182 582  112  HOH HOH B . 
F 3 HOH 183 583  255  HOH HOH B . 
F 3 HOH 184 584  1242 HOH HOH B . 
F 3 HOH 185 585  959  HOH HOH B . 
F 3 HOH 186 586  706  HOH HOH B . 
F 3 HOH 187 587  1176 HOH HOH B . 
F 3 HOH 188 588  202  HOH HOH B . 
F 3 HOH 189 589  377  HOH HOH B . 
F 3 HOH 190 590  1152 HOH HOH B . 
F 3 HOH 191 591  1232 HOH HOH B . 
F 3 HOH 192 592  150  HOH HOH B . 
F 3 HOH 193 593  278  HOH HOH B . 
F 3 HOH 194 594  913  HOH HOH B . 
F 3 HOH 195 595  242  HOH HOH B . 
F 3 HOH 196 596  826  HOH HOH B . 
F 3 HOH 197 597  950  HOH HOH B . 
F 3 HOH 198 598  136  HOH HOH B . 
F 3 HOH 199 599  1225 HOH HOH B . 
F 3 HOH 200 600  256  HOH HOH B . 
F 3 HOH 201 601  764  HOH HOH B . 
F 3 HOH 202 602  299  HOH HOH B . 
F 3 HOH 203 603  512  HOH HOH B . 
F 3 HOH 204 604  433  HOH HOH B . 
F 3 HOH 205 605  148  HOH HOH B . 
F 3 HOH 206 606  524  HOH HOH B . 
F 3 HOH 207 607  187  HOH HOH B . 
F 3 HOH 208 608  188  HOH HOH B . 
F 3 HOH 209 609  79   HOH HOH B . 
F 3 HOH 210 610  251  HOH HOH B . 
F 3 HOH 211 611  121  HOH HOH B . 
F 3 HOH 212 612  726  HOH HOH B . 
F 3 HOH 213 613  445  HOH HOH B . 
F 3 HOH 214 614  275  HOH HOH B . 
F 3 HOH 215 615  1137 HOH HOH B . 
F 3 HOH 216 616  235  HOH HOH B . 
F 3 HOH 217 617  439  HOH HOH B . 
F 3 HOH 218 618  205  HOH HOH B . 
F 3 HOH 219 619  1383 HOH HOH B . 
F 3 HOH 220 620  1390 HOH HOH B . 
F 3 HOH 221 621  286  HOH HOH B . 
F 3 HOH 222 622  576  HOH HOH B . 
F 3 HOH 223 623  288  HOH HOH B . 
F 3 HOH 224 624  771  HOH HOH B . 
F 3 HOH 225 625  448  HOH HOH B . 
F 3 HOH 226 626  59   HOH HOH B . 
F 3 HOH 227 627  1125 HOH HOH B . 
F 3 HOH 228 628  1180 HOH HOH B . 
F 3 HOH 229 629  638  HOH HOH B . 
F 3 HOH 230 630  615  HOH HOH B . 
F 3 HOH 231 631  362  HOH HOH B . 
F 3 HOH 232 632  783  HOH HOH B . 
F 3 HOH 233 633  33   HOH HOH B . 
F 3 HOH 234 634  374  HOH HOH B . 
F 3 HOH 235 635  793  HOH HOH B . 
F 3 HOH 236 636  397  HOH HOH B . 
F 3 HOH 237 637  260  HOH HOH B . 
F 3 HOH 238 638  265  HOH HOH B . 
F 3 HOH 239 639  61   HOH HOH B . 
F 3 HOH 240 640  773  HOH HOH B . 
F 3 HOH 241 641  1367 HOH HOH B . 
F 3 HOH 242 642  118  HOH HOH B . 
F 3 HOH 243 643  646  HOH HOH B . 
F 3 HOH 244 644  920  HOH HOH B . 
F 3 HOH 245 645  376  HOH HOH B . 
F 3 HOH 246 646  750  HOH HOH B . 
F 3 HOH 247 647  635  HOH HOH B . 
F 3 HOH 248 648  300  HOH HOH B . 
F 3 HOH 249 649  1395 HOH HOH B . 
F 3 HOH 250 650  191  HOH HOH B . 
F 3 HOH 251 651  348  HOH HOH B . 
F 3 HOH 252 652  890  HOH HOH B . 
F 3 HOH 253 653  693  HOH HOH B . 
F 3 HOH 254 654  22   HOH HOH B . 
F 3 HOH 255 655  1240 HOH HOH B . 
F 3 HOH 256 656  1017 HOH HOH B . 
F 3 HOH 257 657  16   HOH HOH B . 
F 3 HOH 258 658  171  HOH HOH B . 
F 3 HOH 259 659  228  HOH HOH B . 
F 3 HOH 260 660  274  HOH HOH B . 
F 3 HOH 261 661  1370 HOH HOH B . 
F 3 HOH 262 662  1058 HOH HOH B . 
F 3 HOH 263 663  56   HOH HOH B . 
F 3 HOH 264 664  1165 HOH HOH B . 
F 3 HOH 265 665  42   HOH HOH B . 
F 3 HOH 266 666  1463 HOH HOH B . 
F 3 HOH 267 667  1368 HOH HOH B . 
F 3 HOH 268 668  608  HOH HOH B . 
F 3 HOH 269 669  1305 HOH HOH B . 
F 3 HOH 270 670  471  HOH HOH B . 
F 3 HOH 271 671  650  HOH HOH B . 
F 3 HOH 272 672  392  HOH HOH B . 
F 3 HOH 273 673  849  HOH HOH B . 
F 3 HOH 274 674  385  HOH HOH B . 
F 3 HOH 275 675  1027 HOH HOH B . 
F 3 HOH 276 676  12   HOH HOH B . 
F 3 HOH 277 677  263  HOH HOH B . 
F 3 HOH 278 678  198  HOH HOH B . 
F 3 HOH 279 679  161  HOH HOH B . 
F 3 HOH 280 680  1187 HOH HOH B . 
F 3 HOH 281 681  130  HOH HOH B . 
F 3 HOH 282 682  574  HOH HOH B . 
F 3 HOH 283 683  680  HOH HOH B . 
F 3 HOH 284 684  321  HOH HOH B . 
F 3 HOH 285 685  1360 HOH HOH B . 
F 3 HOH 286 686  62   HOH HOH B . 
F 3 HOH 287 687  72   HOH HOH B . 
F 3 HOH 288 688  1264 HOH HOH B . 
F 3 HOH 289 689  857  HOH HOH B . 
F 3 HOH 290 690  421  HOH HOH B . 
F 3 HOH 291 691  342  HOH HOH B . 
F 3 HOH 292 692  1136 HOH HOH B . 
F 3 HOH 293 693  641  HOH HOH B . 
F 3 HOH 294 694  721  HOH HOH B . 
F 3 HOH 295 695  267  HOH HOH B . 
F 3 HOH 296 696  1127 HOH HOH B . 
F 3 HOH 297 697  708  HOH HOH B . 
F 3 HOH 298 698  979  HOH HOH B . 
F 3 HOH 299 699  1161 HOH HOH B . 
F 3 HOH 300 700  740  HOH HOH B . 
F 3 HOH 301 701  437  HOH HOH B . 
F 3 HOH 302 702  790  HOH HOH B . 
F 3 HOH 303 703  1437 HOH HOH B . 
F 3 HOH 304 704  1312 HOH HOH B . 
F 3 HOH 305 705  1079 HOH HOH B . 
F 3 HOH 306 706  609  HOH HOH B . 
F 3 HOH 307 707  1177 HOH HOH B . 
F 3 HOH 308 708  701  HOH HOH B . 
F 3 HOH 309 709  1164 HOH HOH B . 
F 3 HOH 310 710  279  HOH HOH B . 
F 3 HOH 311 711  671  HOH HOH B . 
F 3 HOH 312 712  19   HOH HOH B . 
F 3 HOH 313 713  245  HOH HOH B . 
F 3 HOH 314 714  246  HOH HOH B . 
F 3 HOH 315 715  306  HOH HOH B . 
F 3 HOH 316 716  383  HOH HOH B . 
F 3 HOH 317 717  307  HOH HOH B . 
F 3 HOH 318 718  863  HOH HOH B . 
F 3 HOH 319 719  1112 HOH HOH B . 
F 3 HOH 320 720  940  HOH HOH B . 
F 3 HOH 321 721  1313 HOH HOH B . 
F 3 HOH 322 722  3    HOH HOH B . 
F 3 HOH 323 723  36   HOH HOH B . 
F 3 HOH 324 724  957  HOH HOH B . 
F 3 HOH 325 725  862  HOH HOH B . 
F 3 HOH 326 726  689  HOH HOH B . 
F 3 HOH 327 727  180  HOH HOH B . 
F 3 HOH 328 728  717  HOH HOH B . 
F 3 HOH 329 729  384  HOH HOH B . 
F 3 HOH 330 730  860  HOH HOH B . 
F 3 HOH 331 731  1218 HOH HOH B . 
F 3 HOH 332 732  583  HOH HOH B . 
F 3 HOH 333 733  409  HOH HOH B . 
F 3 HOH 334 734  49   HOH HOH B . 
F 3 HOH 335 735  811  HOH HOH B . 
F 3 HOH 336 736  103  HOH HOH B . 
F 3 HOH 337 737  1459 HOH HOH B . 
F 3 HOH 338 738  381  HOH HOH B . 
F 3 HOH 339 739  669  HOH HOH B . 
F 3 HOH 340 740  487  HOH HOH B . 
F 3 HOH 341 741  363  HOH HOH B . 
F 3 HOH 342 742  346  HOH HOH B . 
F 3 HOH 343 743  1157 HOH HOH B . 
F 3 HOH 344 744  422  HOH HOH B . 
F 3 HOH 345 745  331  HOH HOH B . 
F 3 HOH 346 746  168  HOH HOH B . 
F 3 HOH 347 747  1109 HOH HOH B . 
F 3 HOH 348 748  1141 HOH HOH B . 
F 3 HOH 349 749  1067 HOH HOH B . 
F 3 HOH 350 750  129  HOH HOH B . 
F 3 HOH 351 751  100  HOH HOH B . 
F 3 HOH 352 752  808  HOH HOH B . 
F 3 HOH 353 753  476  HOH HOH B . 
F 3 HOH 354 754  966  HOH HOH B . 
F 3 HOH 355 755  731  HOH HOH B . 
F 3 HOH 356 756  345  HOH HOH B . 
F 3 HOH 357 757  593  HOH HOH B . 
F 3 HOH 358 758  1011 HOH HOH B . 
F 3 HOH 359 759  261  HOH HOH B . 
F 3 HOH 360 760  329  HOH HOH B . 
F 3 HOH 361 761  675  HOH HOH B . 
F 3 HOH 362 762  637  HOH HOH B . 
F 3 HOH 363 763  897  HOH HOH B . 
F 3 HOH 364 764  1198 HOH HOH B . 
F 3 HOH 365 765  151  HOH HOH B . 
F 3 HOH 366 766  925  HOH HOH B . 
F 3 HOH 367 767  254  HOH HOH B . 
F 3 HOH 368 768  1336 HOH HOH B . 
F 3 HOH 369 769  272  HOH HOH B . 
F 3 HOH 370 770  223  HOH HOH B . 
F 3 HOH 371 771  682  HOH HOH B . 
F 3 HOH 372 772  469  HOH HOH B . 
F 3 HOH 373 773  1093 HOH HOH B . 
F 3 HOH 374 774  595  HOH HOH B . 
F 3 HOH 375 775  946  HOH HOH B . 
F 3 HOH 376 776  745  HOH HOH B . 
F 3 HOH 377 777  787  HOH HOH B . 
F 3 HOH 378 778  1282 HOH HOH B . 
F 3 HOH 379 779  756  HOH HOH B . 
F 3 HOH 380 780  1281 HOH HOH B . 
F 3 HOH 381 781  996  HOH HOH B . 
F 3 HOH 382 782  1178 HOH HOH B . 
F 3 HOH 383 783  1436 HOH HOH B . 
F 3 HOH 384 784  340  HOH HOH B . 
F 3 HOH 385 785  115  HOH HOH B . 
F 3 HOH 386 786  273  HOH HOH B . 
F 3 HOH 387 787  215  HOH HOH B . 
F 3 HOH 388 788  371  HOH HOH B . 
F 3 HOH 389 789  1397 HOH HOH B . 
F 3 HOH 390 790  914  HOH HOH B . 
F 3 HOH 391 791  662  HOH HOH B . 
F 3 HOH 392 792  441  HOH HOH B . 
F 3 HOH 393 793  127  HOH HOH B . 
F 3 HOH 394 794  154  HOH HOH B . 
F 3 HOH 395 795  353  HOH HOH B . 
F 3 HOH 396 796  1106 HOH HOH B . 
F 3 HOH 397 797  451  HOH HOH B . 
F 3 HOH 398 798  876  HOH HOH B . 
F 3 HOH 399 799  505  HOH HOH B . 
F 3 HOH 400 800  1276 HOH HOH B . 
F 3 HOH 401 801  116  HOH HOH B . 
F 3 HOH 402 802  401  HOH HOH B . 
F 3 HOH 403 803  997  HOH HOH B . 
F 3 HOH 404 804  76   HOH HOH B . 
F 3 HOH 405 805  372  HOH HOH B . 
F 3 HOH 406 806  1296 HOH HOH B . 
F 3 HOH 407 807  508  HOH HOH B . 
F 3 HOH 408 808  139  HOH HOH B . 
F 3 HOH 409 809  84   HOH HOH B . 
F 3 HOH 410 810  515  HOH HOH B . 
F 3 HOH 411 811  412  HOH HOH B . 
F 3 HOH 412 812  349  HOH HOH B . 
F 3 HOH 413 813  1273 HOH HOH B . 
F 3 HOH 414 814  921  HOH HOH B . 
F 3 HOH 415 815  853  HOH HOH B . 
F 3 HOH 416 816  258  HOH HOH B . 
F 3 HOH 417 817  1039 HOH HOH B . 
F 3 HOH 418 818  1032 HOH HOH B . 
F 3 HOH 419 819  185  HOH HOH B . 
F 3 HOH 420 820  1212 HOH HOH B . 
F 3 HOH 421 821  343  HOH HOH B . 
F 3 HOH 422 822  673  HOH HOH B . 
F 3 HOH 423 823  965  HOH HOH B . 
F 3 HOH 424 824  1432 HOH HOH B . 
F 3 HOH 425 825  367  HOH HOH B . 
F 3 HOH 426 826  375  HOH HOH B . 
F 3 HOH 427 827  1210 HOH HOH B . 
F 3 HOH 428 828  851  HOH HOH B . 
F 3 HOH 429 829  586  HOH HOH B . 
F 3 HOH 430 830  827  HOH HOH B . 
F 3 HOH 431 831  590  HOH HOH B . 
F 3 HOH 432 832  285  HOH HOH B . 
F 3 HOH 433 833  831  HOH HOH B . 
F 3 HOH 434 834  357  HOH HOH B . 
F 3 HOH 435 835  922  HOH HOH B . 
F 3 HOH 436 836  358  HOH HOH B . 
F 3 HOH 437 837  558  HOH HOH B . 
F 3 HOH 438 838  711  HOH HOH B . 
F 3 HOH 439 839  462  HOH HOH B . 
F 3 HOH 440 840  314  HOH HOH B . 
F 3 HOH 441 841  818  HOH HOH B . 
F 3 HOH 442 842  1022 HOH HOH B . 
F 3 HOH 443 843  895  HOH HOH B . 
F 3 HOH 444 844  748  HOH HOH B . 
F 3 HOH 445 845  930  HOH HOH B . 
F 3 HOH 446 846  364  HOH HOH B . 
F 3 HOH 447 847  1341 HOH HOH B . 
F 3 HOH 448 848  596  HOH HOH B . 
F 3 HOH 449 849  1036 HOH HOH B . 
F 3 HOH 450 850  747  HOH HOH B . 
F 3 HOH 451 851  1160 HOH HOH B . 
F 3 HOH 452 852  830  HOH HOH B . 
F 3 HOH 453 853  1461 HOH HOH B . 
F 3 HOH 454 854  1344 HOH HOH B . 
F 3 HOH 455 855  873  HOH HOH B . 
F 3 HOH 456 856  588  HOH HOH B . 
F 3 HOH 457 857  1451 HOH HOH B . 
F 3 HOH 458 858  488  HOH HOH B . 
F 3 HOH 459 859  629  HOH HOH B . 
F 3 HOH 460 860  810  HOH HOH B . 
F 3 HOH 461 861  1439 HOH HOH B . 
F 3 HOH 462 862  1208 HOH HOH B . 
F 3 HOH 463 863  1369 HOH HOH B . 
F 3 HOH 464 864  1309 HOH HOH B . 
F 3 HOH 465 865  1114 HOH HOH B . 
F 3 HOH 466 866  868  HOH HOH B . 
F 3 HOH 467 867  1234 HOH HOH B . 
F 3 HOH 468 868  1083 HOH HOH B . 
F 3 HOH 469 869  1158 HOH HOH B . 
F 3 HOH 470 870  735  HOH HOH B . 
F 3 HOH 471 871  797  HOH HOH B . 
F 3 HOH 472 872  836  HOH HOH B . 
F 3 HOH 473 873  1287 HOH HOH B . 
F 3 HOH 474 874  1156 HOH HOH B . 
F 3 HOH 475 875  676  HOH HOH B . 
F 3 HOH 476 876  955  HOH HOH B . 
F 3 HOH 477 877  1290 HOH HOH B . 
F 3 HOH 478 878  1243 HOH HOH B . 
F 3 HOH 479 879  795  HOH HOH B . 
F 3 HOH 480 880  1315 HOH HOH B . 
F 3 HOH 481 881  484  HOH HOH B . 
F 3 HOH 482 882  559  HOH HOH B . 
F 3 HOH 483 883  443  HOH HOH B . 
F 3 HOH 484 884  722  HOH HOH B . 
F 3 HOH 485 885  1371 HOH HOH B . 
F 3 HOH 486 886  1040 HOH HOH B . 
F 3 HOH 487 887  611  HOH HOH B . 
F 3 HOH 488 888  1207 HOH HOH B . 
F 3 HOH 489 889  854  HOH HOH B . 
F 3 HOH 490 890  1229 HOH HOH B . 
F 3 HOH 491 891  117  HOH HOH B . 
F 3 HOH 492 892  1252 HOH HOH B . 
F 3 HOH 493 893  800  HOH HOH B . 
F 3 HOH 494 894  763  HOH HOH B . 
F 3 HOH 495 895  941  HOH HOH B . 
F 3 HOH 496 896  1434 HOH HOH B . 
F 3 HOH 497 897  718  HOH HOH B . 
F 3 HOH 498 898  881  HOH HOH B . 
F 3 HOH 499 899  1192 HOH HOH B . 
F 3 HOH 500 900  632  HOH HOH B . 
F 3 HOH 501 901  1072 HOH HOH B . 
F 3 HOH 502 902  729  HOH HOH B . 
F 3 HOH 503 903  1445 HOH HOH B . 
F 3 HOH 504 904  617  HOH HOH B . 
F 3 HOH 505 905  172  HOH HOH B . 
F 3 HOH 506 906  134  HOH HOH B . 
F 3 HOH 507 907  566  HOH HOH B . 
F 3 HOH 508 908  1005 HOH HOH B . 
F 3 HOH 509 909  850  HOH HOH B . 
F 3 HOH 510 910  892  HOH HOH B . 
F 3 HOH 511 911  752  HOH HOH B . 
F 3 HOH 512 912  1239 HOH HOH B . 
F 3 HOH 513 913  872  HOH HOH B . 
F 3 HOH 514 914  298  HOH HOH B . 
F 3 HOH 515 915  1319 HOH HOH B . 
F 3 HOH 516 916  399  HOH HOH B . 
F 3 HOH 517 917  1188 HOH HOH B . 
F 3 HOH 518 918  943  HOH HOH B . 
F 3 HOH 519 919  1280 HOH HOH B . 
F 3 HOH 520 920  903  HOH HOH B . 
F 3 HOH 521 921  529  HOH HOH B . 
F 3 HOH 522 922  1082 HOH HOH B . 
F 3 HOH 523 923  1300 HOH HOH B . 
F 3 HOH 524 924  1052 HOH HOH B . 
F 3 HOH 525 925  820  HOH HOH B . 
F 3 HOH 526 926  262  HOH HOH B . 
F 3 HOH 527 927  1467 HOH HOH B . 
F 3 HOH 528 928  317  HOH HOH B . 
F 3 HOH 529 929  523  HOH HOH B . 
F 3 HOH 530 930  859  HOH HOH B . 
F 3 HOH 531 931  887  HOH HOH B . 
F 3 HOH 532 932  613  HOH HOH B . 
F 3 HOH 533 933  1333 HOH HOH B . 
F 3 HOH 534 934  297  HOH HOH B . 
F 3 HOH 535 935  1061 HOH HOH B . 
F 3 HOH 536 936  435  HOH HOH B . 
F 3 HOH 537 937  933  HOH HOH B . 
F 3 HOH 538 938  1175 HOH HOH B . 
F 3 HOH 539 939  659  HOH HOH B . 
F 3 HOH 540 940  252  HOH HOH B . 
F 3 HOH 541 941  1231 HOH HOH B . 
F 3 HOH 542 942  732  HOH HOH B . 
F 3 HOH 543 943  450  HOH HOH B . 
F 3 HOH 544 944  1008 HOH HOH B . 
F 3 HOH 545 945  96   HOH HOH B . 
F 3 HOH 546 946  1263 HOH HOH B . 
F 3 HOH 547 947  870  HOH HOH B . 
F 3 HOH 548 948  900  HOH HOH B . 
F 3 HOH 549 949  1323 HOH HOH B . 
F 3 HOH 550 950  720  HOH HOH B . 
F 3 HOH 551 951  1028 HOH HOH B . 
F 3 HOH 552 952  954  HOH HOH B . 
F 3 HOH 553 953  447  HOH HOH B . 
F 3 HOH 554 954  846  HOH HOH B . 
F 3 HOH 555 955  674  HOH HOH B . 
F 3 HOH 556 956  1224 HOH HOH B . 
F 3 HOH 557 957  990  HOH HOH B . 
F 3 HOH 558 958  1270 HOH HOH B . 
F 3 HOH 559 959  710  HOH HOH B . 
F 3 HOH 560 960  658  HOH HOH B . 
F 3 HOH 561 961  1086 HOH HOH B . 
F 3 HOH 562 962  527  HOH HOH B . 
F 3 HOH 563 963  1221 HOH HOH B . 
F 3 HOH 564 964  666  HOH HOH B . 
F 3 HOH 565 965  792  HOH HOH B . 
F 3 HOH 566 966  1398 HOH HOH B . 
F 3 HOH 567 967  480  HOH HOH B . 
F 3 HOH 568 968  175  HOH HOH B . 
F 3 HOH 569 969  39   HOH HOH B . 
F 3 HOH 570 970  1460 HOH HOH B . 
F 3 HOH 571 971  359  HOH HOH B . 
F 3 HOH 572 972  1010 HOH HOH B . 
F 3 HOH 573 973  1185 HOH HOH B . 
F 3 HOH 574 974  1306 HOH HOH B . 
F 3 HOH 575 975  1314 HOH HOH B . 
F 3 HOH 576 976  403  HOH HOH B . 
F 3 HOH 577 977  1087 HOH HOH B . 
F 3 HOH 578 978  209  HOH HOH B . 
F 3 HOH 579 979  1183 HOH HOH B . 
F 3 HOH 580 980  961  HOH HOH B . 
F 3 HOH 581 981  1099 HOH HOH B . 
F 3 HOH 582 982  837  HOH HOH B . 
F 3 HOH 583 983  1347 HOH HOH B . 
F 3 HOH 584 984  835  HOH HOH B . 
F 3 HOH 585 985  746  HOH HOH B . 
F 3 HOH 586 986  1226 HOH HOH B . 
F 3 HOH 587 987  679  HOH HOH B . 
F 3 HOH 588 988  715  HOH HOH B . 
F 3 HOH 589 989  1015 HOH HOH B . 
F 3 HOH 590 990  1119 HOH HOH B . 
F 3 HOH 591 991  1292 HOH HOH B . 
F 3 HOH 592 992  355  HOH HOH B . 
F 3 HOH 593 993  1219 HOH HOH B . 
F 3 HOH 594 994  1298 HOH HOH B . 
F 3 HOH 595 995  1044 HOH HOH B . 
F 3 HOH 596 996  1116 HOH HOH B . 
F 3 HOH 597 997  1228 HOH HOH B . 
F 3 HOH 598 998  1167 HOH HOH B . 
F 3 HOH 599 999  436  HOH HOH B . 
F 3 HOH 600 1000 686  HOH HOH B . 
F 3 HOH 601 1001 683  HOH HOH B . 
F 3 HOH 602 1002 916  HOH HOH B . 
F 3 HOH 603 1003 218  HOH HOH B . 
F 3 HOH 604 1004 1353 HOH HOH B . 
F 3 HOH 605 1005 743  HOH HOH B . 
F 3 HOH 606 1006 891  HOH HOH B . 
F 3 HOH 607 1007 176  HOH HOH B . 
F 3 HOH 608 1008 725  HOH HOH B . 
F 3 HOH 609 1009 552  HOH HOH B . 
F 3 HOH 610 1010 1120 HOH HOH B . 
F 3 HOH 611 1011 988  HOH HOH B . 
F 3 HOH 612 1012 956  HOH HOH B . 
F 3 HOH 613 1013 1048 HOH HOH B . 
F 3 HOH 614 1014 1414 HOH HOH B . 
F 3 HOH 615 1015 1016 HOH HOH B . 
F 3 HOH 616 1016 906  HOH HOH B . 
F 3 HOH 617 1017 283  HOH HOH B . 
F 3 HOH 618 1018 923  HOH HOH B . 
F 3 HOH 619 1019 1220 HOH HOH B . 
F 3 HOH 620 1020 1348 HOH HOH B . 
F 3 HOH 621 1021 1391 HOH HOH B . 
F 3 HOH 622 1022 999  HOH HOH B . 
F 3 HOH 623 1023 1181 HOH HOH B . 
F 3 HOH 624 1024 361  HOH HOH B . 
F 3 HOH 625 1025 320  HOH HOH B . 
F 3 HOH 626 1026 1133 HOH HOH B . 
F 3 HOH 627 1027 1012 HOH HOH B . 
F 3 HOH 628 1028 1006 HOH HOH B . 
F 3 HOH 629 1029 1307 HOH HOH B . 
F 3 HOH 630 1030 893  HOH HOH B . 
F 3 HOH 631 1031 1355 HOH HOH B . 
F 3 HOH 632 1032 749  HOH HOH B . 
F 3 HOH 633 1033 1444 HOH HOH B . 
F 3 HOH 634 1034 1327 HOH HOH B . 
F 3 HOH 635 1035 1321 HOH HOH B . 
F 3 HOH 636 1036 603  HOH HOH B . 
F 3 HOH 637 1037 1050 HOH HOH B . 
F 3 HOH 638 1038 494  HOH HOH B . 
F 3 HOH 639 1039 963  HOH HOH B . 
F 3 HOH 640 1040 1248 HOH HOH B . 
F 3 HOH 641 1041 1358 HOH HOH B . 
F 3 HOH 642 1042 695  HOH HOH B . 
F 3 HOH 643 1043 1286 HOH HOH B . 
F 3 HOH 644 1044 520  HOH HOH B . 
F 3 HOH 645 1045 654  HOH HOH B . 
F 3 HOH 646 1046 1172 HOH HOH B . 
F 3 HOH 647 1047 977  HOH HOH B . 
F 3 HOH 648 1048 703  HOH HOH B . 
F 3 HOH 649 1049 994  HOH HOH B . 
F 3 HOH 650 1050 1403 HOH HOH B . 
F 3 HOH 651 1051 927  HOH HOH B . 
F 3 HOH 652 1052 867  HOH HOH B . 
F 3 HOH 653 1053 780  HOH HOH B . 
F 3 HOH 654 1054 1097 HOH HOH B . 
F 3 HOH 655 1055 768  HOH HOH B . 
F 3 HOH 656 1056 911  HOH HOH B . 
F 3 HOH 657 1057 1223 HOH HOH B . 
F 3 HOH 658 1058 1043 HOH HOH B . 
F 3 HOH 659 1059 1053 HOH HOH B . 
F 3 HOH 660 1060 470  HOH HOH B . 
F 3 HOH 661 1061 1320 HOH HOH B . 
F 3 HOH 662 1062 803  HOH HOH B . 
F 3 HOH 663 1063 1350 HOH HOH B . 
F 3 HOH 664 1064 839  HOH HOH B . 
F 3 HOH 665 1065 1308 HOH HOH B . 
F 3 HOH 666 1066 316  HOH HOH B . 
F 3 HOH 667 1067 841  HOH HOH B . 
F 3 HOH 668 1068 1115 HOH HOH B . 
F 3 HOH 669 1069 1171 HOH HOH B . 
F 3 HOH 670 1070 1096 HOH HOH B . 
F 3 HOH 671 1071 1227 HOH HOH B . 
F 3 HOH 672 1072 657  HOH HOH B . 
F 3 HOH 673 1073 498  HOH HOH B . 
F 3 HOH 674 1074 602  HOH HOH B . 
F 3 HOH 675 1075 896  HOH HOH B . 
F 3 HOH 676 1076 1410 HOH HOH B . 
F 3 HOH 677 1077 1392 HOH HOH B . 
F 3 HOH 678 1078 627  HOH HOH B . 
F 3 HOH 679 1079 626  HOH HOH B . 
F 3 HOH 680 1080 347  HOH HOH B . 
F 3 HOH 681 1081 1018 HOH HOH B . 
F 3 HOH 682 1082 1430 HOH HOH B . 
F 3 HOH 683 1083 1235 HOH HOH B . 
F 3 HOH 684 1084 1364 HOH HOH B . 
F 3 HOH 685 1085 1193 HOH HOH B . 
F 3 HOH 686 1086 1014 HOH HOH B . 
F 3 HOH 687 1087 544  HOH HOH B . 
F 3 HOH 688 1088 1143 HOH HOH B . 
F 3 HOH 689 1089 640  HOH HOH B . 
F 3 HOH 690 1090 697  HOH HOH B . 
F 3 HOH 691 1091 612  HOH HOH B . 
F 3 HOH 692 1092 1085 HOH HOH B . 
F 3 HOH 693 1093 1046 HOH HOH B . 
F 3 HOH 694 1094 1381 HOH HOH B . 
F 3 HOH 695 1095 379  HOH HOH B . 
F 3 HOH 696 1096 1462 HOH HOH B . 
F 3 HOH 697 1097 1261 HOH HOH B . 
F 3 HOH 698 1098 1051 HOH HOH B . 
F 3 HOH 699 1099 713  HOH HOH B . 
F 3 HOH 700 1100 975  HOH HOH B . 
F 3 HOH 701 1101 692  HOH HOH B . 
F 3 HOH 702 1102 1279 HOH HOH B . 
F 3 HOH 703 1103 548  HOH HOH B . 
F 3 HOH 704 1104 500  HOH HOH B . 
F 3 HOH 705 1105 1418 HOH HOH B . 
F 3 HOH 706 1106 1262 HOH HOH B . 
F 3 HOH 707 1107 1415 HOH HOH B . 
F 3 HOH 708 1108 1196 HOH HOH B . 
F 3 HOH 709 1109 1346 HOH HOH B . 
F 3 HOH 710 1110 610  HOH HOH B . 
F 3 HOH 711 1111 214  HOH HOH B . 
F 3 HOH 712 1112 691  HOH HOH B . 
F 3 HOH 713 1113 1326 HOH HOH B . 
F 3 HOH 714 1114 1411 HOH HOH B . 
F 3 HOH 715 1115 1408 HOH HOH B . 
F 3 HOH 716 1116 1435 HOH HOH B . 
F 3 HOH 717 1117 939  HOH HOH B . 
F 3 HOH 718 1118 784  HOH HOH B . 
F 3 HOH 719 1119 32   HOH HOH B . 
F 3 HOH 720 1120 716  HOH HOH B . 
F 3 HOH 721 1121 1154 HOH HOH B . 
F 3 HOH 722 1122 1345 HOH HOH B . 
F 3 HOH 723 1123 1068 HOH HOH B . 
F 3 HOH 724 1124 1268 HOH HOH B . 
F 3 HOH 725 1125 1441 HOH HOH B . 
F 3 HOH 726 1126 1113 HOH HOH B . 
F 3 HOH 727 1127 1433 HOH HOH B . 
F 3 HOH 728 1128 465  HOH HOH B . 
F 3 HOH 729 1129 884  HOH HOH B . 
F 3 HOH 730 1130 389  HOH HOH B . 
F 3 HOH 731 1131 786  HOH HOH B . 
F 3 HOH 732 1132 802  HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLN 19  ? NE2 ? A GLN 53  NE2 
2  1 Y 1 A GLN 21  ? CD  ? A GLN 55  CD  
3  1 Y 1 A GLN 21  ? OE1 ? A GLN 55  OE1 
4  1 Y 1 A GLN 21  ? NE2 ? A GLN 55  NE2 
5  1 Y 1 A GLU 22  ? CD  ? A GLU 56  CD  
6  1 Y 1 A GLU 22  ? OE1 ? A GLU 56  OE1 
7  1 Y 1 A GLU 22  ? OE2 ? A GLU 56  OE2 
8  1 Y 1 A LYS 90  ? CD  ? A LYS 124 CD  
9  1 Y 1 A LYS 90  ? CE  ? A LYS 124 CE  
10 1 Y 1 A LYS 90  ? NZ  ? A LYS 124 NZ  
11 1 Y 1 A GLU 208 ? CG  ? A GLU 242 CG  
12 1 Y 1 A GLU 208 ? CD  ? A GLU 242 CD  
13 1 Y 1 A GLU 208 ? OE1 ? A GLU 242 OE1 
14 1 Y 1 A GLU 208 ? OE2 ? A GLU 242 OE2 
15 1 Y 1 A GLU 227 ? CG  ? A GLU 261 CG  
16 1 Y 1 A GLU 227 ? CD  ? A GLU 261 CD  
17 1 Y 1 A GLU 227 ? OE1 ? A GLU 261 OE1 
18 1 Y 1 A GLU 227 ? OE2 ? A GLU 261 OE2 
19 1 Y 1 A LYS 267 ? CD  ? A LYS 301 CD  
20 1 Y 1 A LYS 267 ? CE  ? A LYS 301 CE  
21 1 Y 1 A LYS 267 ? NZ  ? A LYS 301 NZ  
22 1 Y 1 A ASN 287 ? CG  ? A ASN 321 CG  
23 1 Y 1 A ASN 287 ? OD1 ? A ASN 321 OD1 
24 1 Y 1 A ASN 287 ? ND2 ? A ASN 321 ND2 
25 1 Y 1 A GLU 296 ? CG  ? A GLU 330 CG  
26 1 Y 1 A GLU 296 ? CD  ? A GLU 330 CD  
27 1 Y 1 A GLU 296 ? OE1 ? A GLU 330 OE1 
28 1 Y 1 A GLU 296 ? OE2 ? A GLU 330 OE2 
29 1 Y 1 A VAL 298 ? CG1 ? A VAL 332 CG1 
30 1 Y 1 A VAL 298 ? CG2 ? A VAL 332 CG2 
31 1 Y 1 A GLN 343 ? NE2 ? A GLN 377 NE2 
32 1 Y 1 A LYS 388 ? CE  ? A LYS 422 CE  
33 1 Y 1 A LYS 388 ? NZ  ? A LYS 422 NZ  
34 1 Y 1 B ASP 286 ? CG  ? B ASP 320 CG  
35 1 Y 1 B ASP 286 ? OD1 ? B ASP 320 OD1 
36 1 Y 1 B ASP 286 ? OD2 ? B ASP 320 OD2 
37 1 Y 1 B ASN 288 ? CG  ? B ASN 322 CG  
38 1 Y 1 B ASN 288 ? OD1 ? B ASN 322 OD1 
39 1 Y 1 B ASN 288 ? ND2 ? B ASN 322 ND2 
40 1 Y 1 B VAL 298 ? CG1 ? B VAL 332 CG1 
41 1 Y 1 B VAL 298 ? CG2 ? B VAL 332 CG2 
42 1 Y 1 B LYS 307 ? CG  ? B LYS 341 CG  
43 1 Y 1 B LYS 307 ? CD  ? B LYS 341 CD  
44 1 Y 1 B LYS 307 ? CE  ? B LYS 341 CE  
45 1 Y 1 B LYS 307 ? NZ  ? B LYS 341 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? '(1.20.1_4487: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   113.77 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JOH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     54.659 
_cell.length_a_esd                 ? 
_cell.length_b                     138.577 
_cell.length_b_esd                 ? 
_cell.length_c                     63.038 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JOH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JOH 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.28 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.95 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '24% PEG1500 +20% Glycerol' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            290 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-02 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97853 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL19U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97853 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL19U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9JOH 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.36 
_reflns.d_resolution_low                               69.29 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     182984 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          17.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.82 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.038 
_reflns.pdbx_Rpim_I_all                                0.021 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       597467 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.032 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.36 
_reflns_shell.d_res_low                                     1.43 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           71933 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             26739 
_reflns_shell.percent_possible_obs                          99.6 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               2.7 
_reflns_shell.pdbx_chi_squared                              0.61 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     2.6 
_reflns_shell.pdbx_Rrim_I_all                               0.361 
_reflns_shell.pdbx_Rpim_I_all                               0.209 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.892 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.293 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9JOH 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.36 
_refine.ls_d_res_low                             30.22 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     182917 
_refine.ls_number_reflns_R_free                  1982 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.62 
_refine.ls_percent_reflns_R_free                 1.08 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1459 
_refine.ls_R_factor_R_free                       0.1632 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1457 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 16.62 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.11 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.36 
_refine_hist.d_res_low                        30.22 
_refine_hist.number_atoms_solvent             1456 
_refine_hist.number_atoms_total               7467 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5897 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         114 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012 ? 6162 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.361 ? 8392 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 7.276 ? 812  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.095 ? 938  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.009 ? 1057 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.36 1.39  . . 138 12904 100.00 . . . . 0.2186 . . . . . . . . . . . 0.2470 
'X-RAY DIFFRACTION' 1.39 1.43  . . 140 12942 100.00 . . . . 0.2020 . . . . . . . . . . . 0.2231 
'X-RAY DIFFRACTION' 1.43 1.47  . . 140 12895 100.00 . . . . 0.1911 . . . . . . . . . . . 0.2135 
'X-RAY DIFFRACTION' 1.47 1.52  . . 149 12897 100.00 . . . . 0.1823 . . . . . . . . . . . 0.1821 
'X-RAY DIFFRACTION' 1.52 1.57  . . 138 12913 100.00 . . . . 0.1661 . . . . . . . . . . . 0.1999 
'X-RAY DIFFRACTION' 1.57 1.64  . . 141 12914 100.00 . . . . 0.1589 . . . . . . . . . . . 0.1562 
'X-RAY DIFFRACTION' 1.64 1.71  . . 146 12957 100.00 . . . . 0.1537 . . . . . . . . . . . 0.1840 
'X-RAY DIFFRACTION' 1.71 1.80  . . 137 12916 100.00 . . . . 0.1503 . . . . . . . . . . . 0.1615 
'X-RAY DIFFRACTION' 1.80 1.92  . . 141 12892 100.00 . . . . 0.1494 . . . . . . . . . . . 0.1774 
'X-RAY DIFFRACTION' 1.92 2.06  . . 143 12888 99.00  . . . . 0.1391 . . . . . . . . . . . 0.1739 
'X-RAY DIFFRACTION' 2.06 2.27  . . 141 12952 100.00 . . . . 0.1325 . . . . . . . . . . . 0.1570 
'X-RAY DIFFRACTION' 2.27 2.60  . . 143 12949 100.00 . . . . 0.1329 . . . . . . . . . . . 0.1415 
'X-RAY DIFFRACTION' 2.60 3.27  . . 141 12896 99.00  . . . . 0.1393 . . . . . . . . . . . 0.1563 
'X-RAY DIFFRACTION' 3.27 30.22 . . 144 13020 99.00  . . . . 0.1361 . . . . . . . . . . . 0.1473 
# 
_struct.entry_id                     9JOH 
_struct.title                        
'COMPLEX STRUCTURE OF ENDO-1,3-FUCANASE (FUN168D) WITH FUCOTETRAOSE FROM ISOSTICHOPUS BADIONOTUS' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JOH 
_struct_keywords.text            'Endo-1.3-fucanase, GH168, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A1B1Y6G8_9FLAO 
_struct_ref.pdbx_db_accession          A0A1B1Y6G8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;STKNGIIELEQETEEELEQNQEIDYSNYPEFSWDTMPLYMHVRKNTAYTDEEINYLASFPLITLEKSQAQNTYGSTEEGT
LATASAIKLKNNKAKVLYYRNVVINWGNYKNDDEFISKNPSALLKNQNNELVYMPNGSTPFFDITKSFVQEYWLKSVEDM
VATPNIDGTFIDANIKVLVPSFFSSKVGVNKQAEIENSYFSMMSRLKESLSNNLILANIIRVRPEFEENGLEYLGYFNGS
YLEGFDSEAFGMSNAEYLVEGIEATQKAAQSGKIITMTLGLGEAIDNNTGIDDQREDVDLNDEELNKRVDYLLAIFLICA
EKYSYVYLHDGYLATNSAVWLHQFDQYKKALGAPLGKAIKNGYIYTRKFENLDVWLNLETQTATLTWKE
;
_struct_ref.pdbx_align_begin           22 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JOH A 35 ? 423 ? A0A1B1Y6G8 22 ? 410 ? 1 389 
2 1 9JOH B 35 ? 423 ? A0A1B1Y6G8 22 ? 410 ? 1 389 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9JOH MET A 1  ? UNP A0A1B1Y6G8 ? ? 'initiating methionine' -33 1  
1 9JOH GLY A 2  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -32 2  
1 9JOH SER A 3  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -31 3  
1 9JOH SER A 4  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -30 4  
1 9JOH HIS A 5  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -29 5  
1 9JOH HIS A 6  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -28 6  
1 9JOH HIS A 7  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -27 7  
1 9JOH HIS A 8  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -26 8  
1 9JOH HIS A 9  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -25 9  
1 9JOH HIS A 10 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -24 10 
1 9JOH SER A 11 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -23 11 
1 9JOH SER A 12 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -22 12 
1 9JOH GLY A 13 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -21 13 
1 9JOH LEU A 14 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -20 14 
1 9JOH VAL A 15 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -19 15 
1 9JOH PRO A 16 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -18 16 
1 9JOH ARG A 17 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -17 17 
1 9JOH GLY A 18 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -16 18 
1 9JOH SER A 19 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -15 19 
1 9JOH HIS A 20 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -14 20 
1 9JOH MET A 21 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -13 21 
1 9JOH ALA A 22 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -12 22 
1 9JOH SER A 23 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -11 23 
1 9JOH MET A 24 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -10 24 
1 9JOH THR A 25 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -9  25 
1 9JOH GLY A 26 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -8  26 
1 9JOH GLY A 27 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -7  27 
1 9JOH GLN A 28 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -6  28 
1 9JOH GLN A 29 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -5  29 
1 9JOH MET A 30 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -4  30 
1 9JOH GLY A 31 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -3  31 
1 9JOH ARG A 32 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -2  32 
1 9JOH GLY A 33 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -1  33 
1 9JOH SER A 34 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        0   34 
2 9JOH MET B 1  ? UNP A0A1B1Y6G8 ? ? 'initiating methionine' -33 35 
2 9JOH GLY B 2  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -32 36 
2 9JOH SER B 3  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -31 37 
2 9JOH SER B 4  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -30 38 
2 9JOH HIS B 5  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -29 39 
2 9JOH HIS B 6  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -28 40 
2 9JOH HIS B 7  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -27 41 
2 9JOH HIS B 8  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -26 42 
2 9JOH HIS B 9  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -25 43 
2 9JOH HIS B 10 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -24 44 
2 9JOH SER B 11 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -23 45 
2 9JOH SER B 12 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -22 46 
2 9JOH GLY B 13 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -21 47 
2 9JOH LEU B 14 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -20 48 
2 9JOH VAL B 15 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -19 49 
2 9JOH PRO B 16 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -18 50 
2 9JOH ARG B 17 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -17 51 
2 9JOH GLY B 18 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -16 52 
2 9JOH SER B 19 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -15 53 
2 9JOH HIS B 20 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -14 54 
2 9JOH MET B 21 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -13 55 
2 9JOH ALA B 22 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -12 56 
2 9JOH SER B 23 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -11 57 
2 9JOH MET B 24 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -10 58 
2 9JOH THR B 25 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -9  59 
2 9JOH GLY B 26 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -8  60 
2 9JOH GLY B 27 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -7  61 
2 9JOH GLN B 28 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -6  62 
2 9JOH GLN B 29 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -5  63 
2 9JOH MET B 30 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -4  64 
2 9JOH GLY B 31 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -3  65 
2 9JOH ARG B 32 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -2  66 
2 9JOH GLY B 33 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -1  67 
2 9JOH SER B 34 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        0   68 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 83  ? SER A 92  ? THR A 49  SER A 58  1 ? 10 
HELX_P HELX_P2  AA2 ALA A 103 ? GLY A 108 ? ALA A 69  GLY A 74  1 ? 6  
HELX_P HELX_P3  AA3 SER A 109 ? ASN A 125 ? SER A 75  ASN A 91  1 ? 17 
HELX_P HELX_P4  AA4 TYR A 143 ? ASN A 153 ? TYR A 109 ASN A 119 1 ? 11 
HELX_P HELX_P5  AA5 PRO A 154 ? LEU A 157 ? PRO A 120 LEU A 123 5 ? 4  
HELX_P HELX_P6  AA6 LYS A 180 ? ALA A 196 ? LYS A 146 ALA A 162 1 ? 17 
HELX_P HELX_P7  AA7 ALA A 207 ? VAL A 213 ? ALA A 173 VAL A 179 1 ? 7  
HELX_P HELX_P8  AA8 VAL A 213 ? GLY A 222 ? VAL A 179 GLY A 188 1 ? 10 
HELX_P HELX_P9  AA9 GLY A 222 ? LEU A 244 ? GLY A 188 LEU A 210 1 ? 23 
HELX_P HELX_P10 AB1 GLY A 264 ? PHE A 271 ? GLY A 230 PHE A 237 5 ? 8  
HELX_P HELX_P11 AB2 SER A 287 ? SER A 305 ? SER A 253 SER A 271 1 ? 19 
HELX_P HELX_P12 AB3 LEU A 315 ? ASP A 320 ? LEU A 281 ASP A 286 1 ? 6  
HELX_P HELX_P13 AB4 ASP A 336 ? ALA A 354 ? ASP A 302 ALA A 320 1 ? 19 
HELX_P HELX_P14 AB5 LEU A 367 ? SER A 371 ? LEU A 333 SER A 337 5 ? 5  
HELX_P HELX_P15 AB6 PHE A 378 ? LYS A 382 ? PHE A 344 LYS A 348 5 ? 5  
HELX_P HELX_P16 AB7 THR B 83  ? SER B 92  ? THR B 49  SER B 58  1 ? 10 
HELX_P HELX_P17 AB8 ALA B 103 ? GLY B 108 ? ALA B 69  GLY B 74  1 ? 6  
HELX_P HELX_P18 AB9 SER B 109 ? ASN B 125 ? SER B 75  ASN B 91  1 ? 17 
HELX_P HELX_P19 AC1 TYR B 143 ? ASN B 153 ? TYR B 109 ASN B 119 1 ? 11 
HELX_P HELX_P20 AC2 PRO B 154 ? LEU B 157 ? PRO B 120 LEU B 123 5 ? 4  
HELX_P HELX_P21 AC3 LYS B 180 ? THR B 197 ? LYS B 146 THR B 163 1 ? 18 
HELX_P HELX_P22 AC4 ALA B 207 ? VAL B 213 ? ALA B 173 VAL B 179 1 ? 7  
HELX_P HELX_P23 AC5 PRO B 214 ? GLY B 222 ? PRO B 180 GLY B 188 1 ? 9  
HELX_P HELX_P24 AC6 GLY B 222 ? LEU B 244 ? GLY B 188 LEU B 210 1 ? 23 
HELX_P HELX_P25 AC7 GLY B 264 ? PHE B 271 ? GLY B 230 PHE B 237 5 ? 8  
HELX_P HELX_P26 AC8 SER B 287 ? SER B 305 ? SER B 253 SER B 271 1 ? 19 
HELX_P HELX_P27 AC9 LEU B 315 ? ASP B 320 ? LEU B 281 ASP B 286 1 ? 6  
HELX_P HELX_P28 AD1 ASP B 336 ? ALA B 354 ? ASP B 302 ALA B 320 1 ? 19 
HELX_P HELX_P29 AD2 LEU B 367 ? SER B 371 ? LEU B 333 SER B 337 5 ? 5  
HELX_P HELX_P30 AD3 PHE B 378 ? LYS B 382 ? PHE B 344 LYS B 348 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale one  ? C X6Y . O3 ? ? ? 1_555 C X2Y . C1 ? ? D X6Y 1 D X2Y 2 1_555 ? ? ? ? ? ? ? 1.403 ? ? 
covale2 covale both ? C X2Y . O3 ? ? ? 1_555 C FUC . C1 ? ? D X2Y 2 D FUC 3 1_555 ? ? ? ? ? ? ? 1.389 ? ? 
covale3 covale one  ? C FUC . O3 ? ? ? 1_555 C X6Y . C1 ? ? D FUC 3 D X6Y 4 1_555 ? ? ? ? ? ? ? 1.428 ? ? 
covale4 covale one  ? D X6Y . O3 ? ? ? 1_555 D X2Y . C1 ? ? C X6Y 1 C X2Y 2 1_555 ? ? ? ? ? ? ? 1.406 ? ? 
covale5 covale both ? D X2Y . O3 ? ? ? 1_555 D FUC . C1 ? ? C X2Y 2 C FUC 3 1_555 ? ? ? ? ? ? ? 1.388 ? ? 
covale6 covale one  ? D FUC . O3 ? ? ? 1_555 D X6Y . C1 ? ? C FUC 3 C X6Y 4 1_555 ? ? ? ? ? ? ? 1.452 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 4 ? 
AA3 ? 8 ? 
AA4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA3 7 8 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 73  ? LYS A 78  ? TYR A 39  LYS A 44  
AA1 2 LEU A 95  ? GLN A 102 ? LEU A 61  GLN A 68  
AA1 3 LYS A 129 ? ASN A 135 ? LYS A 95  ASN A 101 
AA1 4 GLY A 202 ? ASP A 206 ? GLY A 168 ASP A 172 
AA1 5 LEU A 248 ? ASN A 252 ? LEU A 214 ASN A 218 
AA1 6 GLY A 273 ? LEU A 276 ? GLY A 239 LEU A 242 
AA1 7 ILE A 308 ? GLY A 314 ? ILE A 274 GLY A 280 
AA1 8 SER A 358 ? HIS A 363 ? SER A 324 HIS A 329 
AA2 1 ILE A 393 ? ASN A 395 ? ILE A 359 ASN A 361 
AA2 2 ILE A 398 ? PHE A 403 ? ILE A 364 PHE A 369 
AA2 3 LEU A 406 ? ASN A 411 ? LEU A 372 ASN A 377 
AA2 4 THR A 416 ? TRP A 421 ? THR A 382 TRP A 387 
AA3 1 TYR B 73  ? LYS B 78  ? TYR B 39  LYS B 44  
AA3 2 LEU B 95  ? GLN B 102 ? LEU B 61  GLN B 68  
AA3 3 LYS B 129 ? ASN B 135 ? LYS B 95  ASN B 101 
AA3 4 GLY B 202 ? ASP B 206 ? GLY B 168 ASP B 172 
AA3 5 LEU B 248 ? ASN B 252 ? LEU B 214 ASN B 218 
AA3 6 GLY B 273 ? LEU B 276 ? GLY B 239 LEU B 242 
AA3 7 ILE B 308 ? GLY B 314 ? ILE B 274 GLY B 280 
AA3 8 SER B 358 ? HIS B 363 ? SER B 324 HIS B 329 
AA4 1 ILE B 393 ? ASN B 395 ? ILE B 359 ASN B 361 
AA4 2 ILE B 398 ? PHE B 403 ? ILE B 364 PHE B 369 
AA4 3 LEU B 406 ? ASN B 411 ? LEU B 372 ASN B 377 
AA4 4 THR B 416 ? TRP B 421 ? THR B 382 TRP B 387 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N MET A 74  ? N MET A 40  O THR A 97  ? O THR A 63  
AA1 2 3 N ILE A 96  ? N ILE A 62  O LEU A 131 ? O LEU A 97  
AA1 3 4 N ARG A 134 ? N ARG A 100 O PHE A 204 ? O PHE A 170 
AA1 4 5 N ILE A 205 ? N ILE A 171 O LEU A 250 ? O LEU A 216 
AA1 5 6 N ALA A 251 ? N ALA A 217 O TYR A 275 ? O TYR A 241 
AA1 6 7 N LEU A 276 ? N LEU A 242 O THR A 310 ? O THR A 276 
AA1 7 8 N MET A 311 ? N MET A 277 O TYR A 359 ? O TYR A 325 
AA2 1 2 N ASN A 395 ? N ASN A 361 O ILE A 398 ? O ILE A 364 
AA2 2 3 N PHE A 403 ? N PHE A 369 O LEU A 406 ? O LEU A 372 
AA2 3 4 N ASN A 411 ? N ASN A 377 O THR A 416 ? O THR A 382 
AA3 1 2 N MET B 74  ? N MET B 40  O THR B 97  ? O THR B 63  
AA3 2 3 N ILE B 96  ? N ILE B 62  O LEU B 131 ? O LEU B 97  
AA3 3 4 N ARG B 134 ? N ARG B 100 O PHE B 204 ? O PHE B 170 
AA3 4 5 N ILE B 205 ? N ILE B 171 O LEU B 250 ? O LEU B 216 
AA3 5 6 N ALA B 251 ? N ALA B 217 O TYR B 275 ? O TYR B 241 
AA3 6 7 N LEU B 276 ? N LEU B 242 O THR B 310 ? O THR B 276 
AA3 7 8 N ILE B 309 ? N ILE B 275 O TYR B 359 ? O TYR B 325 
AA4 1 2 N ASN B 395 ? N ASN B 361 O ILE B 398 ? O ILE B 364 
AA4 2 3 N PHE B 403 ? N PHE B 369 O LEU B 406 ? O LEU B 372 
AA4 3 4 N ASN B 411 ? N ASN B 377 O THR B 416 ? O THR B 382 
# 
_pdbx_entry_details.entry_id                   9JOH 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 HO4 D X6Y 4    ? ? O   A HOH 868  ? ? 1.56 
2  1 HZ3 A LYS 125  ? ? O   A HOH 405  ? ? 1.58 
3  1 O9  D X2Y 2    ? ? HO2 D FUC 3    ? ? 1.59 
4  1 O   A HOH 928  ? ? O   B HOH 871  ? ? 1.82 
5  1 O   B HOH 1120 ? ? O   B HOH 1125 ? ? 1.84 
6  1 O   B HOH 782  ? ? O   B HOH 853  ? ? 1.86 
7  1 O   B HOH 404  ? ? O   B HOH 587  ? ? 1.86 
8  1 O   A HOH 1086 ? ? O   B HOH 1089 ? ? 1.87 
9  1 O   B HOH 576  ? ? O   B HOH 823  ? ? 1.88 
10 1 O   A HOH 755  ? ? O   A HOH 807  ? ? 1.91 
11 1 O4  D X6Y 4    ? ? O   A HOH 868  ? ? 1.92 
12 1 O   A HOH 740  ? ? O   B HOH 693  ? ? 1.93 
13 1 O   B HOH 666  ? ? O   B HOH 782  ? ? 1.95 
14 1 O   B HOH 402  ? ? O   B HOH 462  ? ? 1.96 
15 1 O   B HOH 1114 ? ? O   B HOH 1116 ? ? 1.96 
16 1 O   B HOH 707  ? ? O   B HOH 857  ? ? 1.97 
17 1 O   A HOH 928  ? ? O   B HOH 741  ? ? 1.97 
18 1 O   A HOH 803  ? ? O   A HOH 951  ? ? 1.98 
19 1 O   A HOH 412  ? ? O   A HOH 856  ? ? 1.99 
20 1 O   A HOH 516  ? ? O   B HOH 807  ? ? 1.99 
21 1 O   B GLU 283  ? ? O   B HOH 401  ? ? 1.99 
22 1 O   A HOH 647  ? ? O   A HOH 917  ? ? 2.00 
23 1 O   A HOH 420  ? ? O   A HOH 837  ? ? 2.01 
24 1 O   A HOH 408  ? ? O   A HOH 836  ? ? 2.02 
25 1 O   B HOH 620  ? ? O   B HOH 752  ? ? 2.02 
26 1 O   A HOH 820  ? ? O   B HOH 439  ? ? 2.02 
27 1 O   A HOH 861  ? ? O   A HOH 866  ? ? 2.04 
28 1 O   A HOH 787  ? ? O   A HOH 803  ? ? 2.05 
29 1 O   B HOH 748  ? ? O   B HOH 880  ? ? 2.06 
30 1 O   A HOH 824  ? ? O   A HOH 1081 ? ? 2.07 
31 1 O   B HOH 818  ? ? O   B HOH 820  ? ? 2.07 
32 1 O   B HOH 798  ? ? O   B HOH 855  ? ? 2.07 
33 1 O   B HOH 979  ? ? O   B HOH 1114 ? ? 2.08 
34 1 O   A HOH 907  ? ? O   A HOH 1056 ? ? 2.08 
35 1 O   B HOH 764  ? ? O   B HOH 837  ? ? 2.09 
36 1 O   A HOH 842  ? ? O   B HOH 1070 ? ? 2.09 
37 1 O   B HOH 743  ? ? O   B HOH 1049 ? ? 2.09 
38 1 O   A HOH 788  ? ? O   A HOH 971  ? ? 2.09 
39 1 O   A HOH 462  ? ? O   A HOH 786  ? ? 2.10 
40 1 O   A HOH 409  ? ? O   A HOH 631  ? ? 2.11 
41 1 O   B HOH 521  ? ? O   B HOH 806  ? ? 2.11 
42 1 O   A HOH 871  ? ? O   A HOH 925  ? ? 2.11 
43 1 O   A HOH 823  ? ? O   A HOH 1018 ? ? 2.12 
44 1 OH  A TYR 363  ? ? O   A HOH 401  ? ? 2.12 
45 1 O   A HOH 927  ? ? O   A HOH 934  ? ? 2.12 
46 1 O   B HOH 545  ? ? O   B HOH 984  ? ? 2.12 
47 1 O   A HOH 508  ? ? O   A HOH 516  ? ? 2.12 
48 1 O   B HOH 955  ? ? O   B HOH 1063 ? ? 2.13 
49 1 O   A HOH 817  ? ? O   A HOH 1004 ? ? 2.13 
50 1 OD2 A ASP 345  ? ? O   A HOH 402  ? ? 2.13 
51 1 O   A HOH 1063 ? ? O   B HOH 1062 ? ? 2.14 
52 1 O   B HOH 555  ? ? O   B HOH 773  ? ? 2.14 
53 1 O   B HOH 725  ? ? O   B HOH 847  ? ? 2.14 
54 1 O   B HOH 1057 ? ? O   B HOH 1068 ? ? 2.14 
55 1 O   B HOH 1023 ? ? O   B HOH 1039 ? ? 2.16 
56 1 O   A HOH 429  ? ? O   A HOH 847  ? ? 2.17 
57 1 O   A HOH 1060 ? ? O   B HOH 1021 ? ? 2.18 
58 1 O   A HOH 1043 ? ? O   A HOH 1106 ? ? 2.18 
59 1 O   B HOH 496  ? ? O   B HOH 954  ? ? 2.19 
60 1 O   B HOH 666  ? ? O   B HOH 1096 ? ? 2.19 
61 1 O   A HOH 405  ? ? O   A HOH 914  ? ? 2.19 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O A HOH 917 ? ? 1_555 O B HOH 923 ? ? 2_546 1.98 
2 1 O A HOH 798 ? ? 1_555 O B HOH 963 ? ? 1_554 2.05 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN A 108 ? ? 81.46   11.24  
2 1 ALA A 173 ? ? 81.38   15.34  
3 1 ILE A 219 ? ? -134.16 -39.77 
4 1 LEU A 351 ? ? -105.96 -63.53 
5 1 SER B 138 ? ? -133.89 -31.17 
6 1 ILE B 219 ? ? -134.72 -42.12 
7 1 ARG B 221 ? ? -170.67 131.94 
8 1 LEU B 351 ? ? -105.09 -66.61 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1  1 O ? A HOH 1113 ? 5.85 .    
2  1 O ? A HOH 1115 ? 6.02 .    
3  1 O ? A HOH 1116 ? 6.24 .    
4  1 O ? A HOH 1117 ? 6.30 .    
5  1 O ? A HOH 1118 ? 6.42 .    
6  1 O ? A HOH 1119 ? 6.66 .    
7  1 O ? A HOH 1122 ? .    6.81 
8  1 O ? B HOH 1121 ? 5.84 .    
9  1 O ? B HOH 1122 ? 5.86 .    
10 1 O ? B HOH 1124 ? 6.11 .    
11 1 O ? B HOH 1125 ? 6.34 .    
12 1 O ? B HOH 1126 ? 6.41 .    
13 1 O ? B HOH 1127 ? 6.59 .    
14 1 O ? B HOH 1129 ? 6.89 .    
15 1 O ? B HOH 1131 ? .    6.11 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -33 ? A MET 1   
2   1 Y 1 A GLY -32 ? A GLY 2   
3   1 Y 1 A SER -31 ? A SER 3   
4   1 Y 1 A SER -30 ? A SER 4   
5   1 Y 1 A HIS -29 ? A HIS 5   
6   1 Y 1 A HIS -28 ? A HIS 6   
7   1 Y 1 A HIS -27 ? A HIS 7   
8   1 Y 1 A HIS -26 ? A HIS 8   
9   1 Y 1 A HIS -25 ? A HIS 9   
10  1 Y 1 A HIS -24 ? A HIS 10  
11  1 Y 1 A SER -23 ? A SER 11  
12  1 Y 1 A SER -22 ? A SER 12  
13  1 Y 1 A GLY -21 ? A GLY 13  
14  1 Y 1 A LEU -20 ? A LEU 14  
15  1 Y 1 A VAL -19 ? A VAL 15  
16  1 Y 1 A PRO -18 ? A PRO 16  
17  1 Y 1 A ARG -17 ? A ARG 17  
18  1 Y 1 A GLY -16 ? A GLY 18  
19  1 Y 1 A SER -15 ? A SER 19  
20  1 Y 1 A HIS -14 ? A HIS 20  
21  1 Y 1 A MET -13 ? A MET 21  
22  1 Y 1 A ALA -12 ? A ALA 22  
23  1 Y 1 A SER -11 ? A SER 23  
24  1 Y 1 A MET -10 ? A MET 24  
25  1 Y 1 A THR -9  ? A THR 25  
26  1 Y 1 A GLY -8  ? A GLY 26  
27  1 Y 1 A GLY -7  ? A GLY 27  
28  1 Y 1 A GLN -6  ? A GLN 28  
29  1 Y 1 A GLN -5  ? A GLN 29  
30  1 Y 1 A MET -4  ? A MET 30  
31  1 Y 1 A GLY -3  ? A GLY 31  
32  1 Y 1 A ARG -2  ? A ARG 32  
33  1 Y 1 A GLY -1  ? A GLY 33  
34  1 Y 1 A SER 0   ? A SER 34  
35  1 Y 1 A SER 1   ? A SER 35  
36  1 Y 1 A THR 2   ? A THR 36  
37  1 Y 1 A LYS 3   ? A LYS 37  
38  1 Y 1 A ASN 4   ? A ASN 38  
39  1 Y 1 A GLY 5   ? A GLY 39  
40  1 Y 1 A ILE 6   ? A ILE 40  
41  1 Y 1 A ILE 7   ? A ILE 41  
42  1 Y 1 A GLU 8   ? A GLU 42  
43  1 Y 1 A LEU 9   ? A LEU 43  
44  1 Y 1 A GLU 10  ? A GLU 44  
45  1 Y 1 A GLN 11  ? A GLN 45  
46  1 Y 1 A GLU 12  ? A GLU 46  
47  1 Y 1 A THR 13  ? A THR 47  
48  1 Y 1 A GLU 14  ? A GLU 48  
49  1 Y 1 A GLU 15  ? A GLU 49  
50  1 Y 1 A GLU 16  ? A GLU 50  
51  1 Y 1 A GLU 389 ? A GLU 423 
52  1 Y 1 B MET -33 ? B MET 1   
53  1 Y 1 B GLY -32 ? B GLY 2   
54  1 Y 1 B SER -31 ? B SER 3   
55  1 Y 1 B SER -30 ? B SER 4   
56  1 Y 1 B HIS -29 ? B HIS 5   
57  1 Y 1 B HIS -28 ? B HIS 6   
58  1 Y 1 B HIS -27 ? B HIS 7   
59  1 Y 1 B HIS -26 ? B HIS 8   
60  1 Y 1 B HIS -25 ? B HIS 9   
61  1 Y 1 B HIS -24 ? B HIS 10  
62  1 Y 1 B SER -23 ? B SER 11  
63  1 Y 1 B SER -22 ? B SER 12  
64  1 Y 1 B GLY -21 ? B GLY 13  
65  1 Y 1 B LEU -20 ? B LEU 14  
66  1 Y 1 B VAL -19 ? B VAL 15  
67  1 Y 1 B PRO -18 ? B PRO 16  
68  1 Y 1 B ARG -17 ? B ARG 17  
69  1 Y 1 B GLY -16 ? B GLY 18  
70  1 Y 1 B SER -15 ? B SER 19  
71  1 Y 1 B HIS -14 ? B HIS 20  
72  1 Y 1 B MET -13 ? B MET 21  
73  1 Y 1 B ALA -12 ? B ALA 22  
74  1 Y 1 B SER -11 ? B SER 23  
75  1 Y 1 B MET -10 ? B MET 24  
76  1 Y 1 B THR -9  ? B THR 25  
77  1 Y 1 B GLY -8  ? B GLY 26  
78  1 Y 1 B GLY -7  ? B GLY 27  
79  1 Y 1 B GLN -6  ? B GLN 28  
80  1 Y 1 B GLN -5  ? B GLN 29  
81  1 Y 1 B MET -4  ? B MET 30  
82  1 Y 1 B GLY -3  ? B GLY 31  
83  1 Y 1 B ARG -2  ? B ARG 32  
84  1 Y 1 B GLY -1  ? B GLY 33  
85  1 Y 1 B SER 0   ? B SER 34  
86  1 Y 1 B SER 1   ? B SER 35  
87  1 Y 1 B THR 2   ? B THR 36  
88  1 Y 1 B LYS 3   ? B LYS 37  
89  1 Y 1 B ASN 4   ? B ASN 38  
90  1 Y 1 B GLY 5   ? B GLY 39  
91  1 Y 1 B ILE 6   ? B ILE 40  
92  1 Y 1 B ILE 7   ? B ILE 41  
93  1 Y 1 B GLU 8   ? B GLU 42  
94  1 Y 1 B LEU 9   ? B LEU 43  
95  1 Y 1 B GLU 10  ? B GLU 44  
96  1 Y 1 B GLN 11  ? B GLN 45  
97  1 Y 1 B GLU 12  ? B GLU 46  
98  1 Y 1 B THR 13  ? B THR 47  
99  1 Y 1 B GLU 14  ? B GLU 48  
100 1 Y 1 B GLU 15  ? B GLU 49  
101 1 Y 1 B GLU 16  ? B GLU 50  
102 1 Y 1 B LEU 17  ? B LEU 51  
103 1 Y 1 B GLU 18  ? B GLU 52  
104 1 Y 1 B GLN 19  ? B GLN 53  
105 1 Y 1 B ASN 20  ? B ASN 54  
106 1 Y 1 B GLN 21  ? B GLN 55  
107 1 Y 1 B GLU 22  ? B GLU 56  
108 1 Y 1 B GLU 389 ? B GLU 423 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
FUC C1   C N R 88  
FUC C2   C N S 89  
FUC C3   C N R 90  
FUC C4   C N S 91  
FUC C5   C N S 92  
FUC C6   C N N 93  
FUC O1   O N N 94  
FUC O2   O N N 95  
FUC O3   O N N 96  
FUC O4   O N N 97  
FUC O5   O N N 98  
FUC H1   H N N 99  
FUC H2   H N N 100 
FUC H3   H N N 101 
FUC H4   H N N 102 
FUC H5   H N N 103 
FUC H61  H N N 104 
FUC H62  H N N 105 
FUC H63  H N N 106 
FUC HO1  H N N 107 
FUC HO2  H N N 108 
FUC HO3  H N N 109 
FUC HO4  H N N 110 
GLN N    N N N 111 
GLN CA   C N S 112 
GLN C    C N N 113 
GLN O    O N N 114 
GLN CB   C N N 115 
GLN CG   C N N 116 
GLN CD   C N N 117 
GLN OE1  O N N 118 
GLN NE2  N N N 119 
GLN OXT  O N N 120 
GLN H    H N N 121 
GLN H2   H N N 122 
GLN HA   H N N 123 
GLN HB2  H N N 124 
GLN HB3  H N N 125 
GLN HG2  H N N 126 
GLN HG3  H N N 127 
GLN HE21 H N N 128 
GLN HE22 H N N 129 
GLN HXT  H N N 130 
GLU N    N N N 131 
GLU CA   C N S 132 
GLU C    C N N 133 
GLU O    O N N 134 
GLU CB   C N N 135 
GLU CG   C N N 136 
GLU CD   C N N 137 
GLU OE1  O N N 138 
GLU OE2  O N N 139 
GLU OXT  O N N 140 
GLU H    H N N 141 
GLU H2   H N N 142 
GLU HA   H N N 143 
GLU HB2  H N N 144 
GLU HB3  H N N 145 
GLU HG2  H N N 146 
GLU HG3  H N N 147 
GLU HE2  H N N 148 
GLU HXT  H N N 149 
GLY N    N N N 150 
GLY CA   C N N 151 
GLY C    C N N 152 
GLY O    O N N 153 
GLY OXT  O N N 154 
GLY H    H N N 155 
GLY H2   H N N 156 
GLY HA2  H N N 157 
GLY HA3  H N N 158 
GLY HXT  H N N 159 
HIS N    N N N 160 
HIS CA   C N S 161 
HIS C    C N N 162 
HIS O    O N N 163 
HIS CB   C N N 164 
HIS CG   C Y N 165 
HIS ND1  N Y N 166 
HIS CD2  C Y N 167 
HIS CE1  C Y N 168 
HIS NE2  N Y N 169 
HIS OXT  O N N 170 
HIS H    H N N 171 
HIS H2   H N N 172 
HIS HA   H N N 173 
HIS HB2  H N N 174 
HIS HB3  H N N 175 
HIS HD1  H N N 176 
HIS HD2  H N N 177 
HIS HE1  H N N 178 
HIS HE2  H N N 179 
HIS HXT  H N N 180 
HOH O    O N N 181 
HOH H1   H N N 182 
HOH H2   H N N 183 
ILE N    N N N 184 
ILE CA   C N S 185 
ILE C    C N N 186 
ILE O    O N N 187 
ILE CB   C N S 188 
ILE CG1  C N N 189 
ILE CG2  C N N 190 
ILE CD1  C N N 191 
ILE OXT  O N N 192 
ILE H    H N N 193 
ILE H2   H N N 194 
ILE HA   H N N 195 
ILE HB   H N N 196 
ILE HG12 H N N 197 
ILE HG13 H N N 198 
ILE HG21 H N N 199 
ILE HG22 H N N 200 
ILE HG23 H N N 201 
ILE HD11 H N N 202 
ILE HD12 H N N 203 
ILE HD13 H N N 204 
ILE HXT  H N N 205 
LEU N    N N N 206 
LEU CA   C N S 207 
LEU C    C N N 208 
LEU O    O N N 209 
LEU CB   C N N 210 
LEU CG   C N N 211 
LEU CD1  C N N 212 
LEU CD2  C N N 213 
LEU OXT  O N N 214 
LEU H    H N N 215 
LEU H2   H N N 216 
LEU HA   H N N 217 
LEU HB2  H N N 218 
LEU HB3  H N N 219 
LEU HG   H N N 220 
LEU HD11 H N N 221 
LEU HD12 H N N 222 
LEU HD13 H N N 223 
LEU HD21 H N N 224 
LEU HD22 H N N 225 
LEU HD23 H N N 226 
LEU HXT  H N N 227 
LYS N    N N N 228 
LYS CA   C N S 229 
LYS C    C N N 230 
LYS O    O N N 231 
LYS CB   C N N 232 
LYS CG   C N N 233 
LYS CD   C N N 234 
LYS CE   C N N 235 
LYS NZ   N N N 236 
LYS OXT  O N N 237 
LYS H    H N N 238 
LYS H2   H N N 239 
LYS HA   H N N 240 
LYS HB2  H N N 241 
LYS HB3  H N N 242 
LYS HG2  H N N 243 
LYS HG3  H N N 244 
LYS HD2  H N N 245 
LYS HD3  H N N 246 
LYS HE2  H N N 247 
LYS HE3  H N N 248 
LYS HZ1  H N N 249 
LYS HZ2  H N N 250 
LYS HZ3  H N N 251 
LYS HXT  H N N 252 
MET N    N N N 253 
MET CA   C N S 254 
MET C    C N N 255 
MET O    O N N 256 
MET CB   C N N 257 
MET CG   C N N 258 
MET SD   S N N 259 
MET CE   C N N 260 
MET OXT  O N N 261 
MET H    H N N 262 
MET H2   H N N 263 
MET HA   H N N 264 
MET HB2  H N N 265 
MET HB3  H N N 266 
MET HG2  H N N 267 
MET HG3  H N N 268 
MET HE1  H N N 269 
MET HE2  H N N 270 
MET HE3  H N N 271 
MET HXT  H N N 272 
PHE N    N N N 273 
PHE CA   C N S 274 
PHE C    C N N 275 
PHE O    O N N 276 
PHE CB   C N N 277 
PHE CG   C Y N 278 
PHE CD1  C Y N 279 
PHE CD2  C Y N 280 
PHE CE1  C Y N 281 
PHE CE2  C Y N 282 
PHE CZ   C Y N 283 
PHE OXT  O N N 284 
PHE H    H N N 285 
PHE H2   H N N 286 
PHE HA   H N N 287 
PHE HB2  H N N 288 
PHE HB3  H N N 289 
PHE HD1  H N N 290 
PHE HD2  H N N 291 
PHE HE1  H N N 292 
PHE HE2  H N N 293 
PHE HZ   H N N 294 
PHE HXT  H N N 295 
PRO N    N N N 296 
PRO CA   C N S 297 
PRO C    C N N 298 
PRO O    O N N 299 
PRO CB   C N N 300 
PRO CG   C N N 301 
PRO CD   C N N 302 
PRO OXT  O N N 303 
PRO H    H N N 304 
PRO HA   H N N 305 
PRO HB2  H N N 306 
PRO HB3  H N N 307 
PRO HG2  H N N 308 
PRO HG3  H N N 309 
PRO HD2  H N N 310 
PRO HD3  H N N 311 
PRO HXT  H N N 312 
SER N    N N N 313 
SER CA   C N S 314 
SER C    C N N 315 
SER O    O N N 316 
SER CB   C N N 317 
SER OG   O N N 318 
SER OXT  O N N 319 
SER H    H N N 320 
SER H2   H N N 321 
SER HA   H N N 322 
SER HB2  H N N 323 
SER HB3  H N N 324 
SER HG   H N N 325 
SER HXT  H N N 326 
THR N    N N N 327 
THR CA   C N S 328 
THR C    C N N 329 
THR O    O N N 330 
THR CB   C N R 331 
THR OG1  O N N 332 
THR CG2  C N N 333 
THR OXT  O N N 334 
THR H    H N N 335 
THR H2   H N N 336 
THR HA   H N N 337 
THR HB   H N N 338 
THR HG1  H N N 339 
THR HG21 H N N 340 
THR HG22 H N N 341 
THR HG23 H N N 342 
THR HXT  H N N 343 
TRP N    N N N 344 
TRP CA   C N S 345 
TRP C    C N N 346 
TRP O    O N N 347 
TRP CB   C N N 348 
TRP CG   C Y N 349 
TRP CD1  C Y N 350 
TRP CD2  C Y N 351 
TRP NE1  N Y N 352 
TRP CE2  C Y N 353 
TRP CE3  C Y N 354 
TRP CZ2  C Y N 355 
TRP CZ3  C Y N 356 
TRP CH2  C Y N 357 
TRP OXT  O N N 358 
TRP H    H N N 359 
TRP H2   H N N 360 
TRP HA   H N N 361 
TRP HB2  H N N 362 
TRP HB3  H N N 363 
TRP HD1  H N N 364 
TRP HE1  H N N 365 
TRP HE3  H N N 366 
TRP HZ2  H N N 367 
TRP HZ3  H N N 368 
TRP HH2  H N N 369 
TRP HXT  H N N 370 
TYR N    N N N 371 
TYR CA   C N S 372 
TYR C    C N N 373 
TYR O    O N N 374 
TYR CB   C N N 375 
TYR CG   C Y N 376 
TYR CD1  C Y N 377 
TYR CD2  C Y N 378 
TYR CE1  C Y N 379 
TYR CE2  C Y N 380 
TYR CZ   C Y N 381 
TYR OH   O N N 382 
TYR OXT  O N N 383 
TYR H    H N N 384 
TYR H2   H N N 385 
TYR HA   H N N 386 
TYR HB2  H N N 387 
TYR HB3  H N N 388 
TYR HD1  H N N 389 
TYR HD2  H N N 390 
TYR HE1  H N N 391 
TYR HE2  H N N 392 
TYR HH   H N N 393 
TYR HXT  H N N 394 
VAL N    N N N 395 
VAL CA   C N S 396 
VAL C    C N N 397 
VAL O    O N N 398 
VAL CB   C N N 399 
VAL CG1  C N N 400 
VAL CG2  C N N 401 
VAL OXT  O N N 402 
VAL H    H N N 403 
VAL H2   H N N 404 
VAL HA   H N N 405 
VAL HB   H N N 406 
VAL HG11 H N N 407 
VAL HG12 H N N 408 
VAL HG13 H N N 409 
VAL HG21 H N N 410 
VAL HG22 H N N 411 
VAL HG23 H N N 412 
VAL HXT  H N N 413 
X2Y C5   C N S 414 
X2Y C4   C N S 415 
X2Y C3   C N R 416 
X2Y C2   C N S 417 
X2Y C1   C N R 418 
X2Y O5   O N N 419 
X2Y C6   C N N 420 
X2Y O3   O N N 421 
X2Y S1   S N N 422 
X2Y O6   O N N 423 
X2Y O7   O N N 424 
X2Y O8   O N N 425 
X2Y O2   O N N 426 
X2Y S2   S N N 427 
X2Y O9   O N N 428 
X2Y O10  O N N 429 
X2Y O11  O N N 430 
X2Y O4   O N N 431 
X2Y H5   H N N 432 
X2Y H4   H N N 433 
X2Y H3   H N N 434 
X2Y H2   H N N 435 
X2Y H1   H N N 436 
X2Y H61  H N N 437 
X2Y H63  H N N 438 
X2Y H62  H N N 439 
X2Y HO3  H N N 440 
X2Y O1   O N N 441 
X2Y H9   H N N 442 
X2Y H11  H N N 443 
X2Y HO1  H N N 444 
X6Y C5   C N S 445 
X6Y C6   C N N 446 
X6Y C2   C N S 447 
X6Y C4   C N S 448 
X6Y C3   C N R 449 
X6Y C1   C N R 450 
X6Y O5   O N N 451 
X6Y O4   O N N 452 
X6Y O1   O N N 453 
X6Y O3   O N N 454 
X6Y S1   S N N 455 
X6Y O6   O N N 456 
X6Y O7   O N N 457 
X6Y O8   O N N 458 
X6Y O2   O N N 459 
X6Y H5   H N N 460 
X6Y H61  H N N 461 
X6Y H63  H N N 462 
X6Y H62  H N N 463 
X6Y H2   H N N 464 
X6Y H4   H N N 465 
X6Y H3   H N N 466 
X6Y H1   H N N 467 
X6Y HO4  H N N 468 
X6Y HO1  H N N 469 
X6Y HO3  H N N 470 
X6Y H10  H N N 471 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
FUC C1  C2   sing N N 83  
FUC C1  O1   sing N N 84  
FUC C1  O5   sing N N 85  
FUC C1  H1   sing N N 86  
FUC C2  C3   sing N N 87  
FUC C2  O2   sing N N 88  
FUC C2  H2   sing N N 89  
FUC C3  C4   sing N N 90  
FUC C3  O3   sing N N 91  
FUC C3  H3   sing N N 92  
FUC C4  C5   sing N N 93  
FUC C4  O4   sing N N 94  
FUC C4  H4   sing N N 95  
FUC C5  C6   sing N N 96  
FUC C5  O5   sing N N 97  
FUC C5  H5   sing N N 98  
FUC C6  H61  sing N N 99  
FUC C6  H62  sing N N 100 
FUC C6  H63  sing N N 101 
FUC O1  HO1  sing N N 102 
FUC O2  HO2  sing N N 103 
FUC O3  HO3  sing N N 104 
FUC O4  HO4  sing N N 105 
GLN N   CA   sing N N 106 
GLN N   H    sing N N 107 
GLN N   H2   sing N N 108 
GLN CA  C    sing N N 109 
GLN CA  CB   sing N N 110 
GLN CA  HA   sing N N 111 
GLN C   O    doub N N 112 
GLN C   OXT  sing N N 113 
GLN CB  CG   sing N N 114 
GLN CB  HB2  sing N N 115 
GLN CB  HB3  sing N N 116 
GLN CG  CD   sing N N 117 
GLN CG  HG2  sing N N 118 
GLN CG  HG3  sing N N 119 
GLN CD  OE1  doub N N 120 
GLN CD  NE2  sing N N 121 
GLN NE2 HE21 sing N N 122 
GLN NE2 HE22 sing N N 123 
GLN OXT HXT  sing N N 124 
GLU N   CA   sing N N 125 
GLU N   H    sing N N 126 
GLU N   H2   sing N N 127 
GLU CA  C    sing N N 128 
GLU CA  CB   sing N N 129 
GLU CA  HA   sing N N 130 
GLU C   O    doub N N 131 
GLU C   OXT  sing N N 132 
GLU CB  CG   sing N N 133 
GLU CB  HB2  sing N N 134 
GLU CB  HB3  sing N N 135 
GLU CG  CD   sing N N 136 
GLU CG  HG2  sing N N 137 
GLU CG  HG3  sing N N 138 
GLU CD  OE1  doub N N 139 
GLU CD  OE2  sing N N 140 
GLU OE2 HE2  sing N N 141 
GLU OXT HXT  sing N N 142 
GLY N   CA   sing N N 143 
GLY N   H    sing N N 144 
GLY N   H2   sing N N 145 
GLY CA  C    sing N N 146 
GLY CA  HA2  sing N N 147 
GLY CA  HA3  sing N N 148 
GLY C   O    doub N N 149 
GLY C   OXT  sing N N 150 
GLY OXT HXT  sing N N 151 
HIS N   CA   sing N N 152 
HIS N   H    sing N N 153 
HIS N   H2   sing N N 154 
HIS CA  C    sing N N 155 
HIS CA  CB   sing N N 156 
HIS CA  HA   sing N N 157 
HIS C   O    doub N N 158 
HIS C   OXT  sing N N 159 
HIS CB  CG   sing N N 160 
HIS CB  HB2  sing N N 161 
HIS CB  HB3  sing N N 162 
HIS CG  ND1  sing Y N 163 
HIS CG  CD2  doub Y N 164 
HIS ND1 CE1  doub Y N 165 
HIS ND1 HD1  sing N N 166 
HIS CD2 NE2  sing Y N 167 
HIS CD2 HD2  sing N N 168 
HIS CE1 NE2  sing Y N 169 
HIS CE1 HE1  sing N N 170 
HIS NE2 HE2  sing N N 171 
HIS OXT HXT  sing N N 172 
HOH O   H1   sing N N 173 
HOH O   H2   sing N N 174 
ILE N   CA   sing N N 175 
ILE N   H    sing N N 176 
ILE N   H2   sing N N 177 
ILE CA  C    sing N N 178 
ILE CA  CB   sing N N 179 
ILE CA  HA   sing N N 180 
ILE C   O    doub N N 181 
ILE C   OXT  sing N N 182 
ILE CB  CG1  sing N N 183 
ILE CB  CG2  sing N N 184 
ILE CB  HB   sing N N 185 
ILE CG1 CD1  sing N N 186 
ILE CG1 HG12 sing N N 187 
ILE CG1 HG13 sing N N 188 
ILE CG2 HG21 sing N N 189 
ILE CG2 HG22 sing N N 190 
ILE CG2 HG23 sing N N 191 
ILE CD1 HD11 sing N N 192 
ILE CD1 HD12 sing N N 193 
ILE CD1 HD13 sing N N 194 
ILE OXT HXT  sing N N 195 
LEU N   CA   sing N N 196 
LEU N   H    sing N N 197 
LEU N   H2   sing N N 198 
LEU CA  C    sing N N 199 
LEU CA  CB   sing N N 200 
LEU CA  HA   sing N N 201 
LEU C   O    doub N N 202 
LEU C   OXT  sing N N 203 
LEU CB  CG   sing N N 204 
LEU CB  HB2  sing N N 205 
LEU CB  HB3  sing N N 206 
LEU CG  CD1  sing N N 207 
LEU CG  CD2  sing N N 208 
LEU CG  HG   sing N N 209 
LEU CD1 HD11 sing N N 210 
LEU CD1 HD12 sing N N 211 
LEU CD1 HD13 sing N N 212 
LEU CD2 HD21 sing N N 213 
LEU CD2 HD22 sing N N 214 
LEU CD2 HD23 sing N N 215 
LEU OXT HXT  sing N N 216 
LYS N   CA   sing N N 217 
LYS N   H    sing N N 218 
LYS N   H2   sing N N 219 
LYS CA  C    sing N N 220 
LYS CA  CB   sing N N 221 
LYS CA  HA   sing N N 222 
LYS C   O    doub N N 223 
LYS C   OXT  sing N N 224 
LYS CB  CG   sing N N 225 
LYS CB  HB2  sing N N 226 
LYS CB  HB3  sing N N 227 
LYS CG  CD   sing N N 228 
LYS CG  HG2  sing N N 229 
LYS CG  HG3  sing N N 230 
LYS CD  CE   sing N N 231 
LYS CD  HD2  sing N N 232 
LYS CD  HD3  sing N N 233 
LYS CE  NZ   sing N N 234 
LYS CE  HE2  sing N N 235 
LYS CE  HE3  sing N N 236 
LYS NZ  HZ1  sing N N 237 
LYS NZ  HZ2  sing N N 238 
LYS NZ  HZ3  sing N N 239 
LYS OXT HXT  sing N N 240 
MET N   CA   sing N N 241 
MET N   H    sing N N 242 
MET N   H2   sing N N 243 
MET CA  C    sing N N 244 
MET CA  CB   sing N N 245 
MET CA  HA   sing N N 246 
MET C   O    doub N N 247 
MET C   OXT  sing N N 248 
MET CB  CG   sing N N 249 
MET CB  HB2  sing N N 250 
MET CB  HB3  sing N N 251 
MET CG  SD   sing N N 252 
MET CG  HG2  sing N N 253 
MET CG  HG3  sing N N 254 
MET SD  CE   sing N N 255 
MET CE  HE1  sing N N 256 
MET CE  HE2  sing N N 257 
MET CE  HE3  sing N N 258 
MET OXT HXT  sing N N 259 
PHE N   CA   sing N N 260 
PHE N   H    sing N N 261 
PHE N   H2   sing N N 262 
PHE CA  C    sing N N 263 
PHE CA  CB   sing N N 264 
PHE CA  HA   sing N N 265 
PHE C   O    doub N N 266 
PHE C   OXT  sing N N 267 
PHE CB  CG   sing N N 268 
PHE CB  HB2  sing N N 269 
PHE CB  HB3  sing N N 270 
PHE CG  CD1  doub Y N 271 
PHE CG  CD2  sing Y N 272 
PHE CD1 CE1  sing Y N 273 
PHE CD1 HD1  sing N N 274 
PHE CD2 CE2  doub Y N 275 
PHE CD2 HD2  sing N N 276 
PHE CE1 CZ   doub Y N 277 
PHE CE1 HE1  sing N N 278 
PHE CE2 CZ   sing Y N 279 
PHE CE2 HE2  sing N N 280 
PHE CZ  HZ   sing N N 281 
PHE OXT HXT  sing N N 282 
PRO N   CA   sing N N 283 
PRO N   CD   sing N N 284 
PRO N   H    sing N N 285 
PRO CA  C    sing N N 286 
PRO CA  CB   sing N N 287 
PRO CA  HA   sing N N 288 
PRO C   O    doub N N 289 
PRO C   OXT  sing N N 290 
PRO CB  CG   sing N N 291 
PRO CB  HB2  sing N N 292 
PRO CB  HB3  sing N N 293 
PRO CG  CD   sing N N 294 
PRO CG  HG2  sing N N 295 
PRO CG  HG3  sing N N 296 
PRO CD  HD2  sing N N 297 
PRO CD  HD3  sing N N 298 
PRO OXT HXT  sing N N 299 
SER N   CA   sing N N 300 
SER N   H    sing N N 301 
SER N   H2   sing N N 302 
SER CA  C    sing N N 303 
SER CA  CB   sing N N 304 
SER CA  HA   sing N N 305 
SER C   O    doub N N 306 
SER C   OXT  sing N N 307 
SER CB  OG   sing N N 308 
SER CB  HB2  sing N N 309 
SER CB  HB3  sing N N 310 
SER OG  HG   sing N N 311 
SER OXT HXT  sing N N 312 
THR N   CA   sing N N 313 
THR N   H    sing N N 314 
THR N   H2   sing N N 315 
THR CA  C    sing N N 316 
THR CA  CB   sing N N 317 
THR CA  HA   sing N N 318 
THR C   O    doub N N 319 
THR C   OXT  sing N N 320 
THR CB  OG1  sing N N 321 
THR CB  CG2  sing N N 322 
THR CB  HB   sing N N 323 
THR OG1 HG1  sing N N 324 
THR CG2 HG21 sing N N 325 
THR CG2 HG22 sing N N 326 
THR CG2 HG23 sing N N 327 
THR OXT HXT  sing N N 328 
TRP N   CA   sing N N 329 
TRP N   H    sing N N 330 
TRP N   H2   sing N N 331 
TRP CA  C    sing N N 332 
TRP CA  CB   sing N N 333 
TRP CA  HA   sing N N 334 
TRP C   O    doub N N 335 
TRP C   OXT  sing N N 336 
TRP CB  CG   sing N N 337 
TRP CB  HB2  sing N N 338 
TRP CB  HB3  sing N N 339 
TRP CG  CD1  doub Y N 340 
TRP CG  CD2  sing Y N 341 
TRP CD1 NE1  sing Y N 342 
TRP CD1 HD1  sing N N 343 
TRP CD2 CE2  doub Y N 344 
TRP CD2 CE3  sing Y N 345 
TRP NE1 CE2  sing Y N 346 
TRP NE1 HE1  sing N N 347 
TRP CE2 CZ2  sing Y N 348 
TRP CE3 CZ3  doub Y N 349 
TRP CE3 HE3  sing N N 350 
TRP CZ2 CH2  doub Y N 351 
TRP CZ2 HZ2  sing N N 352 
TRP CZ3 CH2  sing Y N 353 
TRP CZ3 HZ3  sing N N 354 
TRP CH2 HH2  sing N N 355 
TRP OXT HXT  sing N N 356 
TYR N   CA   sing N N 357 
TYR N   H    sing N N 358 
TYR N   H2   sing N N 359 
TYR CA  C    sing N N 360 
TYR CA  CB   sing N N 361 
TYR CA  HA   sing N N 362 
TYR C   O    doub N N 363 
TYR C   OXT  sing N N 364 
TYR CB  CG   sing N N 365 
TYR CB  HB2  sing N N 366 
TYR CB  HB3  sing N N 367 
TYR CG  CD1  doub Y N 368 
TYR CG  CD2  sing Y N 369 
TYR CD1 CE1  sing Y N 370 
TYR CD1 HD1  sing N N 371 
TYR CD2 CE2  doub Y N 372 
TYR CD2 HD2  sing N N 373 
TYR CE1 CZ   doub Y N 374 
TYR CE1 HE1  sing N N 375 
TYR CE2 CZ   sing Y N 376 
TYR CE2 HE2  sing N N 377 
TYR CZ  OH   sing N N 378 
TYR OH  HH   sing N N 379 
TYR OXT HXT  sing N N 380 
VAL N   CA   sing N N 381 
VAL N   H    sing N N 382 
VAL N   H2   sing N N 383 
VAL CA  C    sing N N 384 
VAL CA  CB   sing N N 385 
VAL CA  HA   sing N N 386 
VAL C   O    doub N N 387 
VAL C   OXT  sing N N 388 
VAL CB  CG1  sing N N 389 
VAL CB  CG2  sing N N 390 
VAL CB  HB   sing N N 391 
VAL CG1 HG11 sing N N 392 
VAL CG1 HG12 sing N N 393 
VAL CG1 HG13 sing N N 394 
VAL CG2 HG21 sing N N 395 
VAL CG2 HG22 sing N N 396 
VAL CG2 HG23 sing N N 397 
VAL OXT HXT  sing N N 398 
X2Y O7  S1   doub N N 399 
X2Y O8  S1   doub N N 400 
X2Y O6  S1   sing N N 401 
X2Y S1  O2   sing N N 402 
X2Y O2  C2   sing N N 403 
X2Y C2  C1   sing N N 404 
X2Y C2  C3   sing N N 405 
X2Y C1  O5   sing N N 406 
X2Y O5  C5   sing N N 407 
X2Y O3  C3   sing N N 408 
X2Y C3  C4   sing N N 409 
X2Y O4  C4   sing N N 410 
X2Y O4  S2   sing N N 411 
X2Y C5  C4   sing N N 412 
X2Y C5  C6   sing N N 413 
X2Y O9  S2   doub N N 414 
X2Y O10 S2   doub N N 415 
X2Y S2  O11  sing N N 416 
X2Y C5  H5   sing N N 417 
X2Y C4  H4   sing N N 418 
X2Y C3  H3   sing N N 419 
X2Y C2  H2   sing N N 420 
X2Y C1  H1   sing N N 421 
X2Y C6  H61  sing N N 422 
X2Y C6  H63  sing N N 423 
X2Y C6  H62  sing N N 424 
X2Y O3  HO3  sing N N 425 
X2Y C1  O1   sing N N 426 
X2Y O6  H9   sing N N 427 
X2Y O11 H11  sing N N 428 
X2Y O1  HO1  sing N N 429 
X6Y O8  S1   doub N N 430 
X6Y O2  S1   sing N N 431 
X6Y O2  C2   sing N N 432 
X6Y S1  O6   doub N N 433 
X6Y S1  O7   sing N N 434 
X6Y O1  C1   sing N N 435 
X6Y O3  C3   sing N N 436 
X6Y C2  C3   sing N N 437 
X6Y C2  C1   sing N N 438 
X6Y C3  C4   sing N N 439 
X6Y C1  O5   sing N N 440 
X6Y C4  C5   sing N N 441 
X6Y C4  O4   sing N N 442 
X6Y O5  C5   sing N N 443 
X6Y C5  C6   sing N N 444 
X6Y C5  H5   sing N N 445 
X6Y C6  H61  sing N N 446 
X6Y C6  H63  sing N N 447 
X6Y C6  H62  sing N N 448 
X6Y C2  H2   sing N N 449 
X6Y C4  H4   sing N N 450 
X6Y C3  H3   sing N N 451 
X6Y C1  H1   sing N N 452 
X6Y O4  HO4  sing N N 453 
X6Y O1  HO1  sing N N 454 
X6Y O3  HO3  sing N N 455 
X6Y O7  H10  sing N N 456 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           U22A20542 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 X6Y 1 n 
2 X2Y 2 n 
2 FUC 3 n 
2 X6Y 4 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9JOH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.018295 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.008058 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007216 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.017334 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N    . LEU A 1 51  ? -31.919 5.000   16.993 1.00 30.00 ?  17   LEU A N    1 
ATOM   2     C CA   . LEU A 1 51  ? -30.496 5.267   17.178 1.00 30.00 ?  17   LEU A CA   1 
ATOM   3     C C    . LEU A 1 51  ? -29.639 4.415   16.260 1.00 30.00 ?  17   LEU A C    1 
ATOM   4     O O    . LEU A 1 51  ? -30.005 3.303   15.936 1.00 30.00 ?  17   LEU A O    1 
ATOM   5     C CB   . LEU A 1 51  ? -30.065 5.065   18.632 1.00 30.00 ?  17   LEU A CB   1 
ATOM   6     C CG   . LEU A 1 51  ? -30.612 6.074   19.651 1.00 30.00 ?  17   LEU A CG   1 
ATOM   7     C CD1  . LEU A 1 51  ? -30.248 5.685   21.076 1.00 30.00 ?  17   LEU A CD1  1 
ATOM   8     C CD2  . LEU A 1 51  ? -30.153 7.492   19.341 1.00 30.00 ?  17   LEU A CD2  1 
ATOM   9     N N    . GLU A 1 52  ? -28.496 4.953   15.857 1.00 24.33 ?  18   GLU A N    1 
ATOM   10    C CA   . GLU A 1 52  ? -27.615 4.248   14.937 1.00 24.48 ?  18   GLU A CA   1 
ATOM   11    C C    . GLU A 1 52  ? -27.269 2.871   15.489 1.00 25.46 ?  18   GLU A C    1 
ATOM   12    O O    . GLU A 1 52  ? -26.900 2.729   16.657 1.00 27.50 ?  18   GLU A O    1 
ATOM   13    C CB   . GLU A 1 52  ? -26.319 5.054   14.774 1.00 25.31 ?  18   GLU A CB   1 
ATOM   14    C CG   . GLU A 1 52  ? -25.304 4.457   13.793 1.00 22.29 ?  18   GLU A CG   1 
ATOM   15    C CD   . GLU A 1 52  ? -25.724 4.616   12.342 1.00 24.94 ?  18   GLU A CD   1 
ATOM   16    O OE1  . GLU A 1 52  ? -26.747 5.300   12.064 1.00 29.07 ?  18   GLU A OE1  1 
ATOM   17    O OE2  . GLU A 1 52  ? -25.060 4.024   11.465 1.00 27.77 ?  18   GLU A OE2  1 
ATOM   18    H H    . GLU A 1 52  ? -28.216 5.737   16.073 1.00 29.20 ?  18   GLU A H    1 
ATOM   19    H HA   . GLU A 1 52  ? -28.052 4.148   14.077 1.00 29.37 ?  18   GLU A HA   1 
ATOM   20    H HB2  . GLU A 1 52  ? -26.547 5.940   14.452 1.00 30.37 ?  18   GLU A HB2  1 
ATOM   21    H HB3  . GLU A 1 52  ? -25.885 5.116   15.639 1.00 30.37 ?  18   GLU A HB3  1 
ATOM   22    H HG2  . GLU A 1 52  ? -24.452 4.905   13.909 1.00 26.75 ?  18   GLU A HG2  1 
ATOM   23    H HG3  . GLU A 1 52  ? -25.209 3.509   13.975 1.00 26.75 ?  18   GLU A HG3  1 
ATOM   24    N N    . GLN A 1 53  ? -27.365 1.857   14.639 1.00 23.13 ?  19   GLN A N    1 
ATOM   25    C CA   . GLN A 1 53  ? -27.010 0.509   15.049 1.00 23.46 ?  19   GLN A CA   1 
ATOM   26    C C    . GLN A 1 53  ? -25.505 0.291   14.906 1.00 22.29 ?  19   GLN A C    1 
ATOM   27    O O    . GLN A 1 53  ? -24.819 0.983   14.145 1.00 23.00 ?  19   GLN A O    1 
ATOM   28    C CB   . GLN A 1 53  ? -27.742 -0.521  14.178 1.00 36.72 ?  19   GLN A CB   1 
ATOM   29    C CG   . GLN A 1 53  ? -29.256 -0.377  14.187 1.00 36.20 ?  19   GLN A CG   1 
ATOM   30    C CD   . GLN A 1 53  ? -29.937 -1.468  14.997 1.00 54.05 ?  19   GLN A CD   1 
ATOM   31    O OE1  . GLN A 1 53  ? -29.726 -1.562  16.210 1.00 53.51 ?  19   GLN A OE1  1 
ATOM   32    H H    . GLN A 1 53  ? -27.631 1.925   13.824 1.00 27.76 ?  19   GLN A H    1 
ATOM   33    H HA   . GLN A 1 53  ? -27.264 0.379   15.976 1.00 28.16 ?  19   GLN A HA   1 
ATOM   34    H HB2  . GLN A 1 53  ? -27.442 -0.422  13.261 1.00 44.06 ?  19   GLN A HB2  1 
ATOM   35    H HB3  . GLN A 1 53  ? -27.529 -1.410  14.502 1.00 44.06 ?  19   GLN A HB3  1 
ATOM   36    H HG2  . GLN A 1 53  ? -29.491 0.479   14.577 1.00 43.44 ?  19   GLN A HG2  1 
ATOM   37    H HG3  . GLN A 1 53  ? -29.585 -0.429  13.276 1.00 43.44 ?  19   GLN A HG3  1 
ATOM   38    N N    . ASN A 1 54  ? -25.012 -0.717  15.620 1.00 23.85 ?  20   ASN A N    1 
ATOM   39    C CA   . ASN A 1 54  ? -23.603 -1.071  15.535 1.00 25.41 ?  20   ASN A CA   1 
ATOM   40    C C    . ASN A 1 54  ? -23.295 -1.775  14.218 1.00 31.84 ?  20   ASN A C    1 
ATOM   41    O O    . ASN A 1 54  ? -24.106 -2.557  13.702 1.00 26.85 ?  20   ASN A O    1 
ATOM   42    C CB   . ASN A 1 54  ? -23.205 -1.977  16.703 1.00 28.31 ?  20   ASN A CB   1 
ATOM   43    C CG   . ASN A 1 54  ? -23.247 -1.256  18.031 1.00 31.45 ?  20   ASN A CG   1 
ATOM   44    O OD1  . ASN A 1 54  ? -22.701 -0.162  18.165 1.00 29.50 ?  20   ASN A OD1  1 
ATOM   45    N ND2  . ASN A 1 54  ? -23.874 -1.871  19.032 1.00 34.51 ?  20   ASN A ND2  1 
ATOM   46    H H    . ASN A 1 54  ? -25.471 -1.208  16.157 1.00 28.62 ?  20   ASN A H    1 
ATOM   47    H HA   . ASN A 1 54  ? -23.076 -0.259  15.580 1.00 30.49 ?  20   ASN A HA   1 
ATOM   48    H HB2  . ASN A 1 54  ? -23.819 -2.727  16.747 1.00 33.97 ?  20   ASN A HB2  1 
ATOM   49    H HB3  . ASN A 1 54  ? -22.300 -2.298  16.563 1.00 33.97 ?  20   ASN A HB3  1 
ATOM   50    H HD21 . ASN A 1 54  ? -24.230 -2.644  18.906 1.00 41.41 ?  20   ASN A HD21 1 
ATOM   51    H HD22 . ASN A 1 54  ? -23.921 -1.497  19.804 1.00 41.41 ?  20   ASN A HD22 1 
ATOM   52    N N    . GLN A 1 55  ? -22.124 -1.465  13.662 1.00 24.75 ?  21   GLN A N    1 
ATOM   53    C CA   . GLN A 1 55  ? -21.629 -2.117  12.458 1.00 24.45 ?  21   GLN A CA   1 
ATOM   54    C C    . GLN A 1 55  ? -21.106 -3.508  12.800 1.00 26.02 ?  21   GLN A C    1 
ATOM   55    O O    . GLN A 1 55  ? -20.690 -3.773  13.930 1.00 24.15 ?  21   GLN A O    1 
ATOM   56    C CB   . GLN A 1 55  ? -20.478 -1.301  11.853 1.00 35.76 ?  21   GLN A CB   1 
ATOM   57    C CG   . GLN A 1 55  ? -20.564 -1.117  10.346 1.00 46.98 ?  21   GLN A CG   1 
ATOM   58    H H    . GLN A 1 55  ? -21.588 -0.868  13.972 1.00 29.70 ?  21   GLN A H    1 
ATOM   59    H HA   . GLN A 1 55  ? -22.344 -2.189  11.807 1.00 29.34 ?  21   GLN A HA   1 
ATOM   60    H HB2  . GLN A 1 55  ? -20.478 -0.419  12.257 1.00 42.91 ?  21   GLN A HB2  1 
ATOM   61    H HB3  . GLN A 1 55  ? -19.642 -1.754  12.046 1.00 42.91 ?  21   GLN A HB3  1 
ATOM   62    H HG2  . GLN A 1 55  ? -20.784 -1.965  9.932  1.00 56.37 ?  21   GLN A HG2  1 
ATOM   63    H HG3  . GLN A 1 55  ? -21.249 -0.459  10.144 1.00 56.37 ?  21   GLN A HG3  1 
ATOM   64    N N    . GLU A 1 56  ? -21.123 -4.395  11.799 1.00 23.80 ?  22   GLU A N    1 
ATOM   65    C CA   . GLU A 1 56  ? -20.480 -5.700  11.945 1.00 26.58 ?  22   GLU A CA   1 
ATOM   66    C C    . GLU A 1 56  ? -19.000 -5.521  12.254 1.00 24.46 ?  22   GLU A C    1 
ATOM   67    O O    . GLU A 1 56  ? -18.333 -4.659  11.664 1.00 23.84 ?  22   GLU A O    1 
ATOM   68    C CB   . GLU A 1 56  ? -20.583 -6.471  10.633 1.00 24.52 ?  22   GLU A CB   1 
ATOM   69    C CG   . GLU A 1 56  ? -20.191 -7.951  10.775 1.00 38.46 ?  22   GLU A CG   1 
ATOM   70    H H    . GLU A 1 56  ? -21.496 -4.265  11.035 1.00 28.56 ?  22   GLU A H    1 
ATOM   71    H HA   . GLU A 1 56  ? -20.916 -6.191  12.659 1.00 31.90 ?  22   GLU A HA   1 
ATOM   72    H HB2  . GLU A 1 56  ? -21.498 -6.433  10.316 1.00 29.42 ?  22   GLU A HB2  1 
ATOM   73    H HB3  . GLU A 1 56  ? -19.989 -6.065  9.983  1.00 29.42 ?  22   GLU A HB3  1 
ATOM   74    H HG2  . GLU A 1 56  ? -19.414 -8.127  10.223 1.00 46.15 ?  22   GLU A HG2  1 
ATOM   75    H HG3  . GLU A 1 56  ? -19.988 -8.139  11.703 1.00 46.15 ?  22   GLU A HG3  1 
ATOM   76    N N    . ILE A 1 57  ? -18.473 -6.353  13.151 1.00 19.63 ?  23   ILE A N    1 
ATOM   77    C CA   . ILE A 1 57  ? -17.119 -6.116  13.667 1.00 16.89 ?  23   ILE A CA   1 
ATOM   78    C C    . ILE A 1 57  ? -16.084 -6.432  12.600 1.00 21.88 ?  23   ILE A C    1 
ATOM   79    O O    . ILE A 1 57  ? -16.130 -7.490  11.955 1.00 27.63 ?  23   ILE A O    1 
ATOM   80    C CB   . ILE A 1 57  ? -16.896 -6.916  14.967 1.00 27.55 ?  23   ILE A CB   1 
ATOM   81    C CG1  . ILE A 1 57  ? -17.701 -6.292  16.122 1.00 24.95 ?  23   ILE A CG1  1 
ATOM   82    C CG2  . ILE A 1 57  ? -15.412 -6.979  15.330 1.00 38.10 ?  23   ILE A CG2  1 
ATOM   83    C CD1  . ILE A 1 57  ? -17.098 -5.016  16.707 1.00 35.16 ?  23   ILE A CD1  1 
ATOM   84    H H    . ILE A 1 57  ? -18.867 -7.047  13.472 1.00 23.55 ?  23   ILE A H    1 
ATOM   85    H HA   . ILE A 1 57  ? -17.020 -5.174  13.879 1.00 20.26 ?  23   ILE A HA   1 
ATOM   86    H HB   . ILE A 1 57  ? -17.210 -7.821  14.816 1.00 33.06 ?  23   ILE A HB   1 
ATOM   87    H HG12 . ILE A 1 57  ? -18.588 -6.072  15.796 1.00 29.94 ?  23   ILE A HG12 1 
ATOM   88    H HG13 . ILE A 1 57  ? -17.763 -6.941  16.840 1.00 29.94 ?  23   ILE A HG13 1 
ATOM   89    H HG21 . ILE A 1 57  ? -15.318 -7.385  16.206 1.00 45.73 ?  23   ILE A HG21 1 
ATOM   90    H HG22 . ILE A 1 57  ? -14.947 -7.513  14.667 1.00 45.73 ?  23   ILE A HG22 1 
ATOM   91    H HG23 . ILE A 1 57  ? -15.051 -6.079  15.343 1.00 45.73 ?  23   ILE A HG23 1 
ATOM   92    H HD11 . ILE A 1 57  ? -17.707 -4.655  17.370 1.00 42.19 ?  23   ILE A HD11 1 
ATOM   93    H HD12 . ILE A 1 57  ? -16.247 -5.230  17.120 1.00 42.19 ?  23   ILE A HD12 1 
ATOM   94    H HD13 . ILE A 1 57  ? -16.967 -4.373  15.993 1.00 42.19 ?  23   ILE A HD13 1 
ATOM   95    N N    . ASP A 1 58  ? -15.157 -5.499  12.383 1.00 18.71 ?  24   ASP A N    1 
ATOM   96    C CA   . ASP A 1 58  ? -14.025 -5.703  11.495 1.00 20.41 ?  24   ASP A CA   1 
ATOM   97    C C    . ASP A 1 58  ? -12.808 -5.178  12.234 1.00 18.56 ?  24   ASP A C    1 
ATOM   98    O O    . ASP A 1 58  ? -12.740 -3.984  12.526 1.00 20.26 ?  24   ASP A O    1 
ATOM   99    C CB   . ASP A 1 58  ? -14.205 -4.927  10.191 1.00 27.83 ?  24   ASP A CB   1 
ATOM   100   C CG   . ASP A 1 58  ? -12.980 -5.012  9.272  1.00 28.18 ?  24   ASP A CG   1 
ATOM   101   O OD1  . ASP A 1 58  ? -12.005 -5.711  9.607  1.00 26.94 ?  24   ASP A OD1  1 
ATOM   102   O OD2  . ASP A 1 58  ? -13.038 -4.416  8.163  1.00 40.33 ?  24   ASP A OD2  1 
ATOM   103   H H    . ASP A 1 58  ? -15.166 -4.722  12.751 1.00 22.45 ?  24   ASP A H    1 
ATOM   104   H HA   . ASP A 1 58  ? -13.919 -6.643  11.279 1.00 24.49 ?  24   ASP A HA   1 
ATOM   105   H HB2  . ASP A 1 58  ? -14.966 -5.289  9.710  1.00 33.40 ?  24   ASP A HB2  1 
ATOM   106   H HB3  . ASP A 1 58  ? -14.359 -3.992  10.399 1.00 33.40 ?  24   ASP A HB3  1 
ATOM   107   N N    . TYR A 1 59  ? -11.877 -6.053  12.560 1.00 17.10 ?  25   TYR A N    1 
ATOM   108   C CA   . TYR A 1 59  ? -10.709 -5.699  13.347 1.00 16.77 ?  25   TYR A CA   1 
ATOM   109   C C    . TYR A 1 59  ? -9.531  -5.229  12.499 1.00 19.22 ?  25   TYR A C    1 
ATOM   110   O O    . TYR A 1 59  ? -8.439  -5.014  13.044 1.00 17.71 ?  25   TYR A O    1 
ATOM   111   C CB   . TYR A 1 59  ? -10.265 -6.891  14.180 1.00 17.71 ?  25   TYR A CB   1 
ATOM   112   C CG   . TYR A 1 59  ? -11.212 -7.373  15.216 1.00 19.11 ?  25   TYR A CG   1 
ATOM   113   C CD1  . TYR A 1 59  ? -11.788 -6.548  16.159 1.00 22.70 ?  25   TYR A CD1  1 
ATOM   114   C CD2  . TYR A 1 59  ? -11.473 -8.740  15.281 1.00 23.80 ?  25   TYR A CD2  1 
ATOM   115   C CE1  . TYR A 1 59  ? -12.639 -7.093  17.159 1.00 23.64 ?  25   TYR A CE1  1 
ATOM   116   C CE2  . TYR A 1 59  ? -12.294 -9.255  16.200 1.00 25.88 ?  25   TYR A CE2  1 
ATOM   117   C CZ   . TYR A 1 59  ? -12.879 -8.447  17.133 1.00 15.81 ?  25   TYR A CZ   1 
ATOM   118   O OH   . TYR A 1 59  ? -13.660 -8.999  18.112 1.00 21.91 ?  25   TYR A OH   1 
ATOM   119   H H    . TYR A 1 59  ? -11.898 -6.882  12.331 1.00 20.51 ?  25   TYR A H    1 
ATOM   120   H HA   . TYR A 1 59  ? -10.960 -4.975  13.942 1.00 20.12 ?  25   TYR A HA   1 
ATOM   121   H HB2  . TYR A 1 59  ? -10.102 -7.634  13.578 1.00 21.25 ?  25   TYR A HB2  1 
ATOM   122   H HB3  . TYR A 1 59  ? -9.445  -6.649  14.637 1.00 21.25 ?  25   TYR A HB3  1 
ATOM   123   H HD1  . TYR A 1 59  ? -11.619 -5.633  16.141 1.00 27.24 ?  25   TYR A HD1  1 
ATOM   124   H HD2  . TYR A 1 59  ? -11.065 -9.308  14.668 1.00 28.56 ?  25   TYR A HD2  1 
ATOM   125   H HE1  . TYR A 1 59  ? -13.022 -6.551  17.810 1.00 28.36 ?  25   TYR A HE1  1 
ATOM   126   H HE2  . TYR A 1 59  ? -12.467 -10.169 16.204 1.00 31.06 ?  25   TYR A HE2  1 
ATOM   127   H HH   . TYR A 1 59  ? -13.706 -9.831  18.008 1.00 26.29 ?  25   TYR A HH   1 
ATOM   128   N N    . SER A 1 60  ? -9.730  -5.035  11.197 1.00 20.46 ?  26   SER A N    1 
ATOM   129   C CA   . SER A 1 60  ? -8.625  -4.732  10.291 1.00 22.48 ?  26   SER A CA   1 
ATOM   130   C C    . SER A 1 60  ? -7.794  -3.539  10.759 1.00 18.41 ?  26   SER A C    1 
ATOM   131   O O    . SER A 1 60  ? -6.561  -3.562  10.651 1.00 24.13 ?  26   SER A O    1 
ATOM   132   C CB   . SER A 1 60  ? -9.165  -4.471  8.880  1.00 23.47 ?  26   SER A CB   1 
ATOM   133   O OG   . SER A 1 60  ? -9.844  -5.603  8.351  1.00 28.22 ?  26   SER A OG   1 
ATOM   134   H H    . SER A 1 60  ? -10.497 -5.074  10.810 1.00 24.56 ?  26   SER A H    1 
ATOM   135   H HA   . SER A 1 60  ? -8.038  -5.504  10.268 1.00 26.98 ?  26   SER A HA   1 
ATOM   136   H HB2  . SER A 1 60  ? -9.786  -3.726  8.918  1.00 28.17 ?  26   SER A HB2  1 
ATOM   137   H HB3  . SER A 1 60  ? -8.421  -4.254  8.297  1.00 28.17 ?  26   SER A HB3  1 
ATOM   138   H HG   . SER A 1 60  ? -10.493 -5.806  8.844  1.00 33.86 ?  26   SER A HG   1 
ATOM   139   N N    . ASN A 1 61  ? -8.431  -2.501  11.271 1.00 18.63 ?  27   ASN A N    1 
ATOM   140   C CA   . ASN A 1 61  ? -7.733  -1.265  11.619 1.00 20.40 ?  27   ASN A CA   1 
ATOM   141   C C    . ASN A 1 61  ? -7.549  -1.093  13.112 1.00 15.43 ?  27   ASN A C    1 
ATOM   142   O O    . ASN A 1 61  ? -7.190  -0.010  13.577 1.00 16.35 ?  27   ASN A O    1 
ATOM   143   C CB   . ASN A 1 61  ? -8.463  -0.083  10.994 1.00 19.28 ?  27   ASN A CB   1 
ATOM   144   C CG   . ASN A 1 61  ? -8.647  -0.270  9.505  1.00 20.22 ?  27   ASN A CG   1 
ATOM   145   O OD1  . ASN A 1 61  ? -7.696  -0.535  8.801  1.00 24.72 ?  27   ASN A OD1  1 
ATOM   146   N ND2  . ASN A 1 61  ? -9.868  -0.163  9.048  1.00 21.21 ?  27   ASN A ND2  1 
ATOM   147   H H    . ASN A 1 61  ? -9.276  -2.483  11.429 1.00 22.36 ?  27   ASN A H    1 
ATOM   148   H HA   . ASN A 1 61  ? -6.838  -1.282  11.244 1.00 24.48 ?  27   ASN A HA   1 
ATOM   149   H HB2  . ASN A 1 61  ? -9.339  0.005   11.401 1.00 23.14 ?  27   ASN A HB2  1 
ATOM   150   H HB3  . ASN A 1 61  ? -7.948  0.726   11.139 1.00 23.14 ?  27   ASN A HB3  1 
ATOM   151   H HD21 . ASN A 1 61  ? -10.023 -0.262  8.208  1.00 25.45 ?  27   ASN A HD21 1 
ATOM   152   H HD22 . ASN A 1 61  ? -10.516 0.006   9.588  1.00 25.45 ?  27   ASN A HD22 1 
ATOM   153   N N    . TYR A 1 62  ? -7.747  -2.146  13.876 1.00 17.72 ?  28   TYR A N    1 
ATOM   154   C CA   . TYR A 1 62  ? -7.635  -2.035  15.314 1.00 15.35 ?  28   TYR A CA   1 
ATOM   155   C C    . TYR A 1 62  ? -6.176  -2.022  15.749 1.00 14.84 ?  28   TYR A C    1 
ATOM   156   O O    . TYR A 1 62  ? -5.276  -2.474  15.036 1.00 15.60 ?  28   TYR A O    1 
ATOM   157   C CB   . TYR A 1 62  ? -8.339  -3.222  15.977 1.00 13.70 ?  28   TYR A CB   1 
ATOM   158   C CG   . TYR A 1 62  ? -9.796  -3.020  16.313 1.00 13.61 ?  28   TYR A CG   1 
ATOM   159   C CD1  . TYR A 1 62  ? -10.687 -2.469  15.423 1.00 18.21 ?  28   TYR A CD1  1 
ATOM   160   C CD2  . TYR A 1 62  ? -10.268 -3.493  17.537 1.00 15.30 ?  28   TYR A CD2  1 
ATOM   161   C CE1  . TYR A 1 62  ? -12.082 -2.328  15.798 1.00 15.85 ?  28   TYR A CE1  1 
ATOM   162   C CE2  . TYR A 1 62  ? -11.587 -3.391  17.893 1.00 17.82 ?  28   TYR A CE2  1 
ATOM   163   C CZ   . TYR A 1 62  ? -12.465 -2.798  17.046 1.00 14.84 ?  28   TYR A CZ   1 
ATOM   164   O OH   . TYR A 1 62  ? -13.810 -2.788  17.405 1.00 19.95 ?  28   TYR A OH   1 
ATOM   165   H H    . TYR A 1 62  ? -7.946  -2.932  13.588 1.00 21.26 ?  28   TYR A H    1 
ATOM   166   H HA   . TYR A 1 62  ? -8.052  -1.209  15.604 1.00 18.43 ?  28   TYR A HA   1 
ATOM   167   H HB2  . TYR A 1 62  ? -8.286  -3.981  15.375 1.00 16.44 ?  28   TYR A HB2  1 
ATOM   168   H HB3  . TYR A 1 62  ? -7.878  -3.423  16.807 1.00 16.44 ?  28   TYR A HB3  1 
ATOM   169   H HD1  . TYR A 1 62  ? -10.398 -2.188  14.585 1.00 21.85 ?  28   TYR A HD1  1 
ATOM   170   H HD2  . TYR A 1 62  ? -9.670  -3.890  18.129 1.00 18.36 ?  28   TYR A HD2  1 
ATOM   171   H HE1  . TYR A 1 62  ? -12.697 -1.937  15.222 1.00 19.02 ?  28   TYR A HE1  1 
ATOM   172   H HE2  . TYR A 1 62  ? -11.879 -3.726  18.710 1.00 21.38 ?  28   TYR A HE2  1 
ATOM   173   H HH   . TYR A 1 62  ? -13.908 -3.137  18.163 1.00 23.94 ?  28   TYR A HH   1 
ATOM   174   N N    . PRO A 1 63  ? -5.917  -1.511  16.938 1.00 13.33 ?  29   PRO A N    1 
ATOM   175   C CA   . PRO A 1 63  ? -4.555  -1.498  17.472 1.00 12.83 ?  29   PRO A CA   1 
ATOM   176   C C    . PRO A 1 63  ? -4.078  -2.900  17.802 1.00 13.54 ?  29   PRO A C    1 
ATOM   177   O O    . PRO A 1 63  ? -4.851  -3.861  17.852 1.00 14.89 ?  29   PRO A O    1 
ATOM   178   C CB   . PRO A 1 63  ? -4.698  -0.655  18.748 1.00 13.27 ?  29   PRO A CB   1 
ATOM   179   C CG   . PRO A 1 63  ? -6.120  -0.321  18.883 1.00 17.97 ?  29   PRO A CG   1 
ATOM   180   C CD   . PRO A 1 63  ? -6.907  -1.086  17.925 1.00 14.98 ?  29   PRO A CD   1 
ATOM   181   H HA   . PRO A 1 63  ? -3.940  -1.077  16.852 1.00 15.39 ?  29   PRO A HA   1 
ATOM   182   H HB2  . PRO A 1 63  ? -4.395  -1.171  19.511 1.00 15.92 ?  29   PRO A HB2  1 
ATOM   183   H HB3  . PRO A 1 63  ? -4.166  0.152   18.662 1.00 15.92 ?  29   PRO A HB3  1 
ATOM   184   H HG2  . PRO A 1 63  ? -6.404  -0.536  19.786 1.00 21.56 ?  29   PRO A HG2  1 
ATOM   185   H HG3  . PRO A 1 63  ? -6.233  0.628   18.717 1.00 21.56 ?  29   PRO A HG3  1 
ATOM   186   H HD2  . PRO A 1 63  ? -7.320  -1.853  18.351 1.00 17.98 ?  29   PRO A HD2  1 
ATOM   187   H HD3  . PRO A 1 63  ? -7.587  -0.529  17.514 1.00 17.98 ?  29   PRO A HD3  1 
ATOM   188   N N    . GLU A 1 64  ? -2.783  -3.019  18.045 1.00 12.76 ?  30   GLU A N    1 
ATOM   189   C CA   . GLU A 1 64  ? -2.261  -4.250  18.600 1.00 11.63 ?  30   GLU A CA   1 
ATOM   190   C C    . GLU A 1 64  ? -2.835  -4.490  19.984 1.00 13.08 ?  30   GLU A C    1 
ATOM   191   O O    . GLU A 1 64  ? -3.166  -3.551  20.731 1.00 13.62 ?  30   GLU A O    1 
ATOM   192   C CB   . GLU A 1 64  ? -0.747  -4.191  18.711 1.00 14.00 ?  30   GLU A CB   1 
ATOM   193   C CG   . GLU A 1 64  ? -0.011  -3.919  17.414 1.00 14.79 ?  30   GLU A CG   1 
ATOM   194   C CD   . GLU A 1 64  ? -0.312  -4.897  16.313 1.00 22.50 ?  30   GLU A CD   1 
ATOM   195   O OE1  . GLU A 1 64  ? -0.261  -6.120  16.591 1.00 26.85 ?  30   GLU A OE1  1 
ATOM   196   O OE2  . GLU A 1 64  ? -0.571  -4.471  15.169 1.00 26.92 ?  30   GLU A OE2  1 
ATOM   197   H H    . GLU A 1 64  ? -2.194  -2.409  17.899 1.00 15.31 ?  30   GLU A H    1 
ATOM   198   H HA   . GLU A 1 64  ? -2.506  -4.983  18.014 1.00 13.95 ?  30   GLU A HA   1 
ATOM   199   H HB2  . GLU A 1 64  ? -0.513  -3.482  19.330 1.00 16.80 ?  30   GLU A HB2  1 
ATOM   200   H HB3  . GLU A 1 64  ? -0.432  -5.044  19.049 1.00 16.80 ?  30   GLU A HB3  1 
ATOM   201   H HG2  . GLU A 1 64  ? -0.257  -3.036  17.097 1.00 17.75 ?  30   GLU A HG2  1 
ATOM   202   H HG3  . GLU A 1 64  ? 0.943   -3.956  17.585 1.00 17.75 ?  30   GLU A HG3  1 
ATOM   203   N N    . PHE A 1 65  ? -2.943  -5.758  20.361 1.00 13.15 ?  31   PHE A N    1 
ATOM   204   C CA   . PHE A 1 65  ? -3.420  -6.138  21.672 1.00 12.29 ?  31   PHE A CA   1 
ATOM   205   C C    . PHE A 1 65  ? -2.756  -7.447  22.083 1.00 14.81 ?  31   PHE A C    1 
ATOM   206   O O    . PHE A 1 65  ? -2.648  -8.365  21.262 1.00 14.71 ?  31   PHE A O    1 
ATOM   207   C CB   . PHE A 1 65  ? -4.939  -6.312  21.730 1.00 12.99 ?  31   PHE A CB   1 
ATOM   208   C CG   . PHE A 1 65  ? -5.439  -6.683  23.059 1.00 11.05 ?  31   PHE A CG   1 
ATOM   209   C CD1  . PHE A 1 65  ? -5.753  -5.692  24.003 1.00 13.62 ?  31   PHE A CD1  1 
ATOM   210   C CD2  . PHE A 1 65  ? -5.519  -8.028  23.465 1.00 12.68 ?  31   PHE A CD2  1 
ATOM   211   C CE1  . PHE A 1 65  ? -6.178  -6.022  25.276 1.00 12.93 ?  31   PHE A CE1  1 
ATOM   212   C CE2  . PHE A 1 65  ? -5.937  -8.361  24.725 1.00 13.87 ?  31   PHE A CE2  1 
ATOM   213   C CZ   . PHE A 1 65  ? -6.293  -7.359  25.657 1.00 14.10 ?  31   PHE A CZ   1 
ATOM   214   H H    . PHE A 1 65  ? -2.741  -6.428  19.860 1.00 15.78 ?  31   PHE A H    1 
ATOM   215   H HA   . PHE A 1 65  ? -3.175  -5.436  22.295 1.00 14.75 ?  31   PHE A HA   1 
ATOM   216   H HB2  . PHE A 1 65  ? -5.359  -5.474  21.478 1.00 15.59 ?  31   PHE A HB2  1 
ATOM   217   H HB3  . PHE A 1 65  ? -5.196  -7.012  21.110 1.00 15.59 ?  31   PHE A HB3  1 
ATOM   218   H HD1  . PHE A 1 65  ? -5.673  -4.796  23.767 1.00 16.34 ?  31   PHE A HD1  1 
ATOM   219   H HD2  . PHE A 1 65  ? -5.284  -8.701  22.868 1.00 15.21 ?  31   PHE A HD2  1 
ATOM   220   H HE1  . PHE A 1 65  ? -6.389  -5.348  25.882 1.00 15.51 ?  31   PHE A HE1  1 
ATOM   221   H HE2  . PHE A 1 65  ? -5.987  -9.257  24.971 1.00 16.64 ?  31   PHE A HE2  1 
ATOM   222   H HZ   . PHE A 1 65  ? -6.597  -7.586  26.506 1.00 16.92 ?  31   PHE A HZ   1 
ATOM   223   N N    . SER A 1 66  ? -2.368  -7.544  23.336 1.00 13.68 ?  32   SER A N    1 
ATOM   224   C CA   . SER A 1 66  ? -1.908  -8.799  23.909 1.00 13.86 ?  32   SER A CA   1 
ATOM   225   C C    . SER A 1 66  ? -2.358  -8.867  25.349 1.00 15.00 ?  32   SER A C    1 
ATOM   226   O O    . SER A 1 66  ? -2.373  -7.863  26.072 1.00 14.80 ?  32   SER A O    1 
ATOM   227   C CB   . SER A 1 66  ? -0.403  -8.860  23.859 1.00 15.92 ?  32   SER A CB   1 
ATOM   228   O OG   . SER A 1 66  ? 0.072   -10.053 24.502 1.00 16.76 ?  32   SER A OG   1 
ATOM   229   H H    . SER A 1 66  ? -2.359  -6.886  23.890 1.00 16.41 ?  32   SER A H    1 
ATOM   230   H HA   . SER A 1 66  ? -2.284  -9.555  23.431 1.00 16.63 ?  32   SER A HA   1 
ATOM   231   H HB2  . SER A 1 66  ? -0.116  -8.863  22.933 1.00 19.10 ?  32   SER A HB2  1 
ATOM   232   H HB3  . SER A 1 66  ? -0.038  -8.087  24.317 1.00 19.10 ?  32   SER A HB3  1 
ATOM   233   H HG   . SER A 1 66  ? 0.866   -9.947  24.753 1.00 20.11 ?  32   SER A HG   1 
ATOM   234   N N    . TRP A 1 67  ? -2.673  -10.071 25.802 1.00 15.51 ?  33   TRP A N    1 
ATOM   235   C CA   . TRP A 1 67  ? -2.926  -10.318 27.208 1.00 14.84 ?  33   TRP A CA   1 
ATOM   236   C C    . TRP A 1 67  ? -1.650  -10.583 28.011 1.00 13.69 ?  33   TRP A C    1 
ATOM   237   O O    . TRP A 1 67  ? -1.747  -10.810 29.219 1.00 14.78 ?  33   TRP A O    1 
ATOM   238   C CB   . TRP A 1 67  ? -3.832  -11.525 27.379 1.00 15.24 ?  33   TRP A CB   1 
ATOM   239   C CG   . TRP A 1 67  ? -5.267  -11.314 26.980 1.00 13.39 ?  33   TRP A CG   1 
ATOM   240   C CD1  . TRP A 1 67  ? -5.939  -11.912 25.920 1.00 14.92 ?  33   TRP A CD1  1 
ATOM   241   C CD2  . TRP A 1 67  ? -6.261  -10.567 27.684 1.00 13.85 ?  33   TRP A CD2  1 
ATOM   242   N NE1  . TRP A 1 67  ? -7.256  -11.537 25.921 1.00 14.88 ?  33   TRP A NE1  1 
ATOM   243   C CE2  . TRP A 1 67  ? -7.488  -10.690 26.973 1.00 13.88 ?  33   TRP A CE2  1 
ATOM   244   C CE3  . TRP A 1 67  ? -6.233  -9.746  28.819 1.00 15.12 ?  33   TRP A CE3  1 
ATOM   245   C CZ2  . TRP A 1 67  ? -8.659  -10.064 27.398 1.00 13.71 ?  33   TRP A CZ2  1 
ATOM   246   C CZ3  . TRP A 1 67  ? -7.388  -9.119  29.214 1.00 15.77 ?  33   TRP A CZ3  1 
ATOM   247   C CH2  . TRP A 1 67  ? -8.582  -9.280  28.517 1.00 14.22 ?  33   TRP A CH2  1 
ATOM   248   H H    . TRP A 1 67  ? -2.747  -10.770 25.307 1.00 18.62 ?  33   TRP A H    1 
ATOM   249   H HA   . TRP A 1 67  ? -3.370  -9.533  27.565 1.00 17.81 ?  33   TRP A HA   1 
ATOM   250   H HB2  . TRP A 1 67  ? -3.483  -12.248 26.834 1.00 18.29 ?  33   TRP A HB2  1 
ATOM   251   H HB3  . TRP A 1 67  ? -3.826  -11.782 28.314 1.00 18.29 ?  33   TRP A HB3  1 
ATOM   252   H HD1  . TRP A 1 67  ? -5.549  -12.484 25.300 1.00 17.90 ?  33   TRP A HD1  1 
ATOM   253   H HE1  . TRP A 1 67  ? -7.845  -11.794 25.350 1.00 17.85 ?  33   TRP A HE1  1 
ATOM   254   H HE3  . TRP A 1 67  ? -5.445  -9.627  29.297 1.00 18.14 ?  33   TRP A HE3  1 
ATOM   255   H HZ2  . TRP A 1 67  ? -9.460  -10.176 26.940 1.00 16.45 ?  33   TRP A HZ2  1 
ATOM   256   H HZ3  . TRP A 1 67  ? -7.373  -8.574  29.966 1.00 18.93 ?  33   TRP A HZ3  1 
ATOM   257   H HH2  . TRP A 1 67  ? -9.346  -8.844  28.819 1.00 17.06 ?  33   TRP A HH2  1 
ATOM   258   N N    . ASP A 1 68  ? -0.485  -10.565 27.383 1.00 14.14 ?  34   ASP A N    1 
ATOM   259   C CA   . ASP A 1 68  ? 0.719   -11.035 28.079 1.00 14.30 ?  34   ASP A CA   1 
ATOM   260   C C    . ASP A 1 68  ? 0.993   -10.217 29.340 1.00 16.11 ?  34   ASP A C    1 
ATOM   261   O O    . ASP A 1 68  ? 1.382   -10.775 30.384 1.00 16.43 ?  34   ASP A O    1 
ATOM   262   C CB   . ASP A 1 68  ? 1.924   -10.977 27.156 1.00 17.58 ?  34   ASP A CB   1 
ATOM   263   C CG   . ASP A 1 68  ? 1.931   -12.056 26.081 1.00 18.71 ?  34   ASP A CG   1 
ATOM   264   O OD1  . ASP A 1 68  ? 1.074   -12.954 26.090 1.00 21.63 ?  34   ASP A OD1  1 
ATOM   265   O OD2  . ASP A 1 68  ? 2.830   -11.941 25.220 1.00 23.43 ?  34   ASP A OD2  1 
ATOM   266   H H    . ASP A 1 68  ? -0.360  -10.294 26.576 1.00 16.96 ?  34   ASP A H    1 
ATOM   267   H HA   . ASP A 1 68  ? 0.575   -11.959 28.337 1.00 17.16 ?  34   ASP A HA   1 
ATOM   268   H HB2  . ASP A 1 68  ? 1.933   -10.116 26.709 1.00 21.10 ?  34   ASP A HB2  1 
ATOM   269   H HB3  . ASP A 1 68  ? 2.728   -11.084 27.687 1.00 21.10 ?  34   ASP A HB3  1 
ATOM   270   N N    . THR A 1 69  ? 0.852   -8.886  29.247 1.00 15.10 ?  35   THR A N    1 
ATOM   271   C CA   . THR A 1 69  ? 0.981   -7.951  30.365 1.00 14.89 ?  35   THR A CA   1 
ATOM   272   C C    . THR A 1 69  ? -0.135  -6.926  30.223 1.00 14.04 ?  35   THR A C    1 
ATOM   273   O O    . THR A 1 69  ? -0.867  -6.917  29.236 1.00 13.95 ?  35   THR A O    1 
ATOM   274   C CB   . THR A 1 69  ? 2.355   -7.269  30.365 1.00 15.41 ?  35   THR A CB   1 
ATOM   275   O OG1  . THR A 1 69  ? 2.538   -6.557  29.149 1.00 16.94 ?  35   THR A OG1  1 
ATOM   276   C CG2  . THR A 1 69  ? 3.474   -8.298  30.525 1.00 17.72 ?  35   THR A CG2  1 
ATOM   277   H H    . THR A 1 69  ? 0.672   -8.485  28.508 1.00 18.12 ?  35   THR A H    1 
ATOM   278   H HA   . THR A 1 69  ? 0.885   -8.413  31.212 1.00 17.86 ?  35   THR A HA   1 
ATOM   279   H HB   . THR A 1 69  ? 2.404   -6.651  31.111 1.00 18.49 ?  35   THR A HB   1 
ATOM   280   H HG1  . THR A 1 69  ? 1.943   -5.970  29.068 1.00 20.33 ?  35   THR A HG1  1 
ATOM   281   H HG21 . THR A 1 69  ? 4.324   -7.848  30.651 1.00 21.26 ?  35   THR A HG21 1 
ATOM   282   H HG22 . THR A 1 69  ? 3.300   -8.861  31.296 1.00 21.26 ?  35   THR A HG22 1 
ATOM   283   H HG23 . THR A 1 69  ? 3.528   -8.856  29.734 1.00 21.26 ?  35   THR A HG23 1 
ATOM   284   N N    . MET A 1 70  ? -0.263  -6.023  31.203 1.00 14.41 ?  36   MET A N    1 
ATOM   285   C CA   . MET A 1 70  ? -1.334  -5.031  31.191 1.00 14.75 ?  36   MET A CA   1 
ATOM   286   C C    . MET A 1 70  ? -1.457  -4.301  29.862 1.00 13.19 ?  36   MET A C    1 
ATOM   287   O O    . MET A 1 70  ? -0.482  -3.718  29.385 1.00 13.48 ?  36   MET A O    1 
ATOM   288   C CB   . MET A 1 70  ? -1.151  -4.013  32.329 1.00 13.27 ?  36   MET A CB   1 
ATOM   289   C CG   . MET A 1 70  ? -2.453  -3.341  32.748 1.00 16.80 ?  36   MET A CG   1 
ATOM   290   S SD   . MET A 1 70  ? -3.698  -4.347  33.461 1.00 15.70 ?  36   MET A SD   1 
ATOM   291   C CE   . MET A 1 70  ? -2.624  -5.187  34.766 1.00 19.46 ?  36   MET A CE   1 
ATOM   292   H H    . MET A 1 70  ? 0.258   -5.967  31.885 1.00 17.29 ?  36   MET A H    1 
ATOM   293   H HA   . MET A 1 70  ? -2.160  -5.518  31.334 1.00 17.70 ?  36   MET A HA   1 
ATOM   294   H HB2  . MET A 1 70  ? -0.789  -4.470  33.104 1.00 15.93 ?  36   MET A HB2  1 
ATOM   295   H HB3  . MET A 1 70  ? -0.539  -3.320  32.036 1.00 15.93 ?  36   MET A HB3  1 
ATOM   296   H HG2  . MET A 1 70  ? -2.237  -2.659  33.403 1.00 20.15 ?  36   MET A HG2  1 
ATOM   297   H HG3  . MET A 1 70  ? -2.843  -2.932  31.959 1.00 20.15 ?  36   MET A HG3  1 
ATOM   298   H HE1  . MET A 1 70  ? -3.175  -5.791  35.288 1.00 23.36 ?  36   MET A HE1  1 
ATOM   299   H HE2  . MET A 1 70  ? -1.919  -5.684  34.322 1.00 23.36 ?  36   MET A HE2  1 
ATOM   300   H HE3  . MET A 1 70  ? -2.238  -4.509  35.342 1.00 23.36 ?  36   MET A HE3  1 
ATOM   301   N N    . PRO A 1 71  ? -2.657  -4.268  29.276 1.00 13.67 ?  37   PRO A N    1 
ATOM   302   C CA   . PRO A 1 71  ? -2.863  -3.471  28.053 1.00 13.09 ?  37   PRO A CA   1 
ATOM   303   C C    . PRO A 1 71  ? -3.062  -2.010  28.435 1.00 12.18 ?  37   PRO A C    1 
ATOM   304   O O    . PRO A 1 71  ? -3.964  -1.678  29.204 1.00 12.74 ?  37   PRO A O    1 
ATOM   305   C CB   . PRO A 1 71  ? -4.119  -4.090  27.439 1.00 13.37 ?  37   PRO A CB   1 
ATOM   306   C CG   . PRO A 1 71  ? -4.855  -4.675  28.598 1.00 14.49 ?  37   PRO A CG   1 
ATOM   307   C CD   . PRO A 1 71  ? -3.816  -5.146  29.561 1.00 13.28 ?  37   PRO A CD   1 
ATOM   308   H HA   . PRO A 1 71  ? -2.126  -3.557  27.428 1.00 15.71 ?  37   PRO A HA   1 
ATOM   309   H HB2  . PRO A 1 71  ? -4.646  -3.404  27.001 1.00 16.04 ?  37   PRO A HB2  1 
ATOM   310   H HB3  . PRO A 1 71  ? -3.872  -4.777  26.800 1.00 16.04 ?  37   PRO A HB3  1 
ATOM   311   H HG2  . PRO A 1 71  ? -5.415  -3.994  29.005 1.00 17.39 ?  37   PRO A HG2  1 
ATOM   312   H HG3  . PRO A 1 71  ? -5.402  -5.416  28.295 1.00 17.39 ?  37   PRO A HG3  1 
ATOM   313   H HD2  . PRO A 1 71  ? -4.117  -5.033  30.476 1.00 15.93 ?  37   PRO A HD2  1 
ATOM   314   H HD3  . PRO A 1 71  ? -3.592  -6.075  29.398 1.00 15.93 ?  37   PRO A HD3  1 
ATOM   315   N N    . LEU A 1 72  ? -2.200  -1.149  27.897 1.00 12.48 ?  38   LEU A N    1 
ATOM   316   C CA   . LEU A 1 72  ? -2.103  0.248   28.327 1.00 11.55 ?  38   LEU A CA   1 
ATOM   317   C C    . LEU A 1 72  ? -2.519  1.241   27.254 1.00 12.10 ?  38   LEU A C    1 
ATOM   318   O O    . LEU A 1 72  ? -2.228  1.048   26.077 1.00 13.08 ?  38   LEU A O    1 
ATOM   319   C CB   . LEU A 1 72  ? -0.689  0.597   28.760 1.00 14.04 ?  38   LEU A CB   1 
ATOM   320   C CG   . LEU A 1 72  ? -0.126  -0.244  29.891 1.00 12.96 ?  38   LEU A CG   1 
ATOM   321   C CD1  . LEU A 1 72  ? 1.328   0.135   30.143 1.00 15.04 ?  38   LEU A CD1  1 
ATOM   322   C CD2  . LEU A 1 72  ? -0.921  -0.129  31.153 1.00 14.10 ?  38   LEU A CD2  1 
ATOM   323   H H    . LEU A 1 72  ? -1.650  -1.353  27.268 1.00 14.98 ?  38   LEU A H    1 
ATOM   324   H HA   . LEU A 1 72  ? -2.722  0.345   29.068 1.00 13.86 ?  38   LEU A HA   1 
ATOM   325   H HB2  . LEU A 1 72  ? -0.101  0.486   27.996 1.00 16.85 ?  38   LEU A HB2  1 
ATOM   326   H HB3  . LEU A 1 72  ? -0.681  1.521   29.054 1.00 16.85 ?  38   LEU A HB3  1 
ATOM   327   H HG   . LEU A 1 72  ? -0.176  -1.175  29.622 1.00 15.55 ?  38   LEU A HG   1 
ATOM   328   H HD11 . LEU A 1 72  ? 1.695   -0.452  30.822 1.00 18.05 ?  38   LEU A HD11 1 
ATOM   329   H HD12 . LEU A 1 72  ? 1.827   0.038   29.317 1.00 18.05 ?  38   LEU A HD12 1 
ATOM   330   H HD13 . LEU A 1 72  ? 1.366   1.056   30.446 1.00 18.05 ?  38   LEU A HD13 1 
ATOM   331   H HD21 . LEU A 1 72  ? -0.505  -0.674  31.839 1.00 16.92 ?  38   LEU A HD21 1 
ATOM   332   H HD22 . LEU A 1 72  ? -0.937  0.800   31.432 1.00 16.92 ?  38   LEU A HD22 1 
ATOM   333   H HD23 . LEU A 1 72  ? -1.825  -0.440  30.986 1.00 16.92 ?  38   LEU A HD23 1 
ATOM   334   N N    . TYR A 1 73  ? -3.191  2.319   27.697 1.00 11.16 ?  39   TYR A N    1 
ATOM   335   C CA   . TYR A 1 73  ? -3.604  3.451   26.881 1.00 11.83 ?  39   TYR A CA   1 
ATOM   336   C C    . TYR A 1 73  ? -2.833  4.697   27.299 1.00 12.48 ?  39   TYR A C    1 
ATOM   337   O O    . TYR A 1 73  ? -2.537  4.884   28.467 1.00 12.21 ?  39   TYR A O    1 
ATOM   338   C CB   . TYR A 1 73  ? -5.087  3.709   27.176 1.00 13.80 ?  39   TYR A CB   1 
ATOM   339   C CG   . TYR A 1 73  ? -5.747  4.929   26.549 1.00 10.23 ?  39   TYR A CG   1 
ATOM   340   C CD1  . TYR A 1 73  ? -5.771  5.082   25.195 1.00 11.07 ?  39   TYR A CD1  1 
ATOM   341   C CD2  . TYR A 1 73  ? -6.391  5.866   27.329 1.00 10.55 ?  39   TYR A CD2  1 
ATOM   342   C CE1  . TYR A 1 73  ? -6.419  6.167   24.600 1.00 11.62 ?  39   TYR A CE1  1 
ATOM   343   C CE2  . TYR A 1 73  ? -7.062  6.946   26.765 1.00 10.75 ?  39   TYR A CE2  1 
ATOM   344   C CZ   . TYR A 1 73  ? -7.069  7.082   25.403 1.00 10.73 ?  39   TYR A CZ   1 
ATOM   345   O OH   . TYR A 1 73  ? -7.689  8.144   24.770 1.00 11.87 ?  39   TYR A OH   1 
ATOM   346   H H    . TYR A 1 73  ? -3.428  2.413   28.518 1.00 13.39 ?  39   TYR A H    1 
ATOM   347   H HA   . TYR A 1 73  ? -3.443  3.284   25.939 1.00 14.20 ?  39   TYR A HA   1 
ATOM   348   H HB2  . TYR A 1 73  ? -5.586  2.936   26.870 1.00 16.56 ?  39   TYR A HB2  1 
ATOM   349   H HB3  . TYR A 1 73  ? -5.183  3.807   28.137 1.00 16.56 ?  39   TYR A HB3  1 
ATOM   350   H HD1  . TYR A 1 73  ? -5.347  4.452   24.657 1.00 13.28 ?  39   TYR A HD1  1 
ATOM   351   H HD2  . TYR A 1 73  ? -6.377  5.774   28.254 1.00 12.66 ?  39   TYR A HD2  1 
ATOM   352   H HE1  . TYR A 1 73  ? -6.413  6.270   23.675 1.00 13.95 ?  39   TYR A HE1  1 
ATOM   353   H HE2  . TYR A 1 73  ? -7.499  7.565   27.304 1.00 12.90 ?  39   TYR A HE2  1 
ATOM   354   H HH   . TYR A 1 73  ? -8.297  8.455   25.259 1.00 14.24 ?  39   TYR A HH   1 
ATOM   355   N N    . MET A 1 74  ? -2.574  5.584   26.351 1.00 11.17 ?  40   MET A N    1 
ATOM   356   C CA   . MET A 1 74  ? -1.976  6.874   26.649 1.00 10.31 ?  40   MET A CA   1 
ATOM   357   C C    . MET A 1 74  ? -2.848  7.964   26.046 1.00 11.79 ?  40   MET A C    1 
ATOM   358   O O    . MET A 1 74  ? -3.383  7.810   24.943 1.00 11.95 ?  40   MET A O    1 
ATOM   359   C CB   . MET A 1 74  ? -0.543  6.940   26.114 1.00 12.28 ?  40   MET A CB   1 
ATOM   360   C CG   . MET A 1 74  ? 0.190   8.278   26.402 1.00 14.33 ?  40   MET A CG   1 
ATOM   361   S SD   . MET A 1 74  ? 0.112   8.889   28.115 1.00 12.84 ?  40   MET A SD   1 
ATOM   362   C CE   . MET A 1 74  ? 0.757   7.489   29.033 1.00 14.85 ?  40   MET A CE   1 
ATOM   363   H H    . MET A 1 74  ? -2.738  5.459   25.516 1.00 13.41 ?  40   MET A H    1 
ATOM   364   H HA   . MET A 1 74  ? -1.928  7.020   27.607 1.00 12.38 ?  40   MET A HA   1 
ATOM   365   H HB2  . MET A 1 74  ? -0.027  6.229   26.525 1.00 14.73 ?  40   MET A HB2  1 
ATOM   366   H HB3  . MET A 1 74  ? -0.566  6.819   25.152 1.00 14.73 ?  40   MET A HB3  1 
ATOM   367   H HG2  . MET A 1 74  ? 1.128   8.162   26.183 1.00 17.20 ?  40   MET A HG2  1 
ATOM   368   H HG3  . MET A 1 74  ? -0.200  8.964   25.837 1.00 17.20 ?  40   MET A HG3  1 
ATOM   369   H HE1  . MET A 1 74  ? 0.781   7.714   29.976 1.00 17.82 ?  40   MET A HE1  1 
ATOM   370   H HE2  . MET A 1 74  ? 0.179   6.724   28.889 1.00 17.82 ?  40   MET A HE2  1 
ATOM   371   H HE3  . MET A 1 74  ? 1.653   7.291   28.718 1.00 17.82 ?  40   MET A HE3  1 
ATOM   372   N N    . HIS A 1 75  ? -2.968  9.070   26.776 1.00 10.93 ?  41   HIS A N    1 
ATOM   373   C CA   . HIS A 1 75  ? -3.881  10.171  26.445 1.00 10.92 ?  41   HIS A CA   1 
ATOM   374   C C    . HIS A 1 75  ? -3.123  11.400  26.949 1.00 11.91 ?  41   HIS A C    1 
ATOM   375   O O    . HIS A 1 75  ? -2.954  11.550  28.159 1.00 11.67 ?  41   HIS A O    1 
ATOM   376   C CB   . HIS A 1 75  ? -5.205  9.955   27.187 1.00 10.60 ?  41   HIS A CB   1 
ATOM   377   C CG   . HIS A 1 75  ? -6.278  10.885  26.750 1.00 11.16 ?  41   HIS A CG   1 
ATOM   378   N ND1  . HIS A 1 75  ? -7.393  10.504  26.023 1.00 11.16 ?  41   HIS A ND1  1 
ATOM   379   C CD2  . HIS A 1 75  ? -6.422  12.203  26.997 1.00 10.26 ?  41   HIS A CD2  1 
ATOM   380   C CE1  . HIS A 1 75  ? -8.142  11.570  25.810 1.00 11.34 ?  41   HIS A CE1  1 
ATOM   381   N NE2  . HIS A 1 75  ? -7.574  12.615  26.402 1.00 11.23 ?  41   HIS A NE2  1 
ATOM   382   H H    . HIS A 1 75  ? -2.517  9.216   27.494 1.00 13.11 ?  41   HIS A H    1 
ATOM   383   H HA   . HIS A 1 75  ? -4.085  10.261  25.501 1.00 13.11 ?  41   HIS A HA   1 
ATOM   384   H HB2  . HIS A 1 75  ? -5.511  9.049   27.025 1.00 12.72 ?  41   HIS A HB2  1 
ATOM   385   H HB3  . HIS A 1 75  ? -5.059  10.092  28.136 1.00 12.72 ?  41   HIS A HB3  1 
ATOM   386   H HD2  . HIS A 1 75  ? -5.838  12.735  27.488 1.00 12.32 ?  41   HIS A HD2  1 
ATOM   387   H HE1  . HIS A 1 75  ? -8.936  11.586  25.326 1.00 13.61 ?  41   HIS A HE1  1 
ATOM   388   H HE2  . HIS A 1 75  ? -7.883  13.417  26.408 1.00 13.47 ?  41   HIS A HE2  1 
ATOM   389   N N    . VAL A 1 76  ? -2.636  12.252  26.045 1.00 9.85  ?  42   VAL A N    1 
ATOM   390   C CA   . VAL A 1 76  ? -1.566  13.176  26.445 1.00 11.90 ?  42   VAL A CA   1 
ATOM   391   C C    . VAL A 1 76  ? -1.513  14.444  25.620 1.00 10.85 ?  42   VAL A C    1 
ATOM   392   O O    . VAL A 1 76  ? -1.838  14.489  24.434 1.00 10.23 ?  42   VAL A O    1 
ATOM   393   C CB   . VAL A 1 76  ? -0.209  12.436  26.366 1.00 12.22 ?  42   VAL A CB   1 
ATOM   394   C CG1  . VAL A 1 76  ? 0.139   12.070  24.937 1.00 13.56 ?  42   VAL A CG1  1 
ATOM   395   C CG2  . VAL A 1 76  ? 0.964   13.164  27.064 1.00 13.54 ?  42   VAL A CG2  1 
ATOM   396   H H    . VAL A 1 76  ? -2.895  12.312  25.227 1.00 11.81 ?  42   VAL A H    1 
ATOM   397   H HA   . VAL A 1 76  ? -1.777  13.482  27.341 1.00 14.28 ?  42   VAL A HA   1 
ATOM   398   H HB   . VAL A 1 76  ? -0.331  11.618  26.872 1.00 14.66 ?  42   VAL A HB   1 
ATOM   399   H HG11 . VAL A 1 76  ? 0.908   11.478  24.941 1.00 16.27 ?  42   VAL A HG11 1 
ATOM   400   H HG12 . VAL A 1 76  ? -0.620  11.623  24.531 1.00 16.27 ?  42   VAL A HG12 1 
ATOM   401   H HG13 . VAL A 1 76  ? 0.348   12.880  24.446 1.00 16.27 ?  42   VAL A HG13 1 
ATOM   402   H HG21 . VAL A 1 76  ? 1.716   12.555  27.136 1.00 16.25 ?  42   VAL A HG21 1 
ATOM   403   H HG22 . VAL A 1 76  ? 1.215   13.938  26.536 1.00 16.25 ?  42   VAL A HG22 1 
ATOM   404   H HG23 . VAL A 1 76  ? 0.681   13.444  27.949 1.00 16.25 ?  42   VAL A HG23 1 
ATOM   405   N N    . ARG A 1 77  ? -1.034  15.515  26.278 1.00 11.08 ?  43   ARG A N    1 
ATOM   406   C CA   . ARG A 1 77  ? -0.583  16.741  25.644 1.00 10.40 ?  43   ARG A CA   1 
ATOM   407   C C    . ARG A 1 77  ? 0.680   17.225  26.356 1.00 11.36 ?  43   ARG A C    1 
ATOM   408   O O    . ARG A 1 77  ? 0.999   16.824  27.484 1.00 11.69 ?  43   ARG A O    1 
ATOM   409   C CB   . ARG A 1 77  ? -1.644  17.840  25.616 1.00 11.49 ?  43   ARG A CB   1 
ATOM   410   C CG   . ARG A 1 77  ? -2.086  18.270  26.982 1.00 10.63 ?  43   ARG A CG   1 
ATOM   411   C CD   . ARG A 1 77  ? -3.190  19.286  26.929 1.00 11.03 ?  43   ARG A CD   1 
ATOM   412   N NE   . ARG A 1 77  ? -3.652  19.725  28.251 1.00 12.33 ?  43   ARG A NE   1 
ATOM   413   C CZ   . ARG A 1 77  ? -3.191  20.776  28.901 1.00 12.46 ?  43   ARG A CZ   1 
ATOM   414   N NH1  . ARG A 1 77  ? -2.225  21.517  28.407 1.00 11.66 ?  43   ARG A NH1  1 
ATOM   415   N NH2  . ARG A 1 77  ? -3.751  21.096  30.061 1.00 13.97 ?  43   ARG A NH2  1 
ATOM   416   H H    . ARG A 1 77  ? -0.961  15.546  27.135 1.00 13.30 ?  43   ARG A H    1 
ATOM   417   H HA   . ARG A 1 77  ? -0.369  16.540  24.720 1.00 12.48 ?  43   ARG A HA   1 
ATOM   418   H HB2  . ARG A 1 77  ? -1.281  18.616  25.162 1.00 13.78 ?  43   ARG A HB2  1 
ATOM   419   H HB3  . ARG A 1 77  ? -2.423  17.512  25.140 1.00 13.78 ?  43   ARG A HB3  1 
ATOM   420   H HG2  . ARG A 1 77  ? -2.410  17.497  27.470 1.00 12.76 ?  43   ARG A HG2  1 
ATOM   421   H HG3  . ARG A 1 77  ? -1.334  18.667  27.449 1.00 12.76 ?  43   ARG A HG3  1 
ATOM   422   H HD2  . ARG A 1 77  ? -2.872  20.068  26.452 1.00 13.24 ?  43   ARG A HD2  1 
ATOM   423   H HD3  . ARG A 1 77  ? -3.948  18.899  26.464 1.00 13.24 ?  43   ARG A HD3  1 
ATOM   424   H HE   . ARG A 1 77  ? -4.270  19.262  28.631 1.00 14.79 ?  43   ARG A HE   1 
ATOM   425   H HH11 . ARG A 1 77  ? -1.879  21.321  27.644 1.00 14.00 ?  43   ARG A HH11 1 
ATOM   426   H HH12 . ARG A 1 77  ? -1.939  22.199  28.846 1.00 14.00 ?  43   ARG A HH12 1 
ATOM   427   H HH21 . ARG A 1 77  ? -4.398  20.622  30.371 1.00 16.77 ?  43   ARG A HH21 1 
ATOM   428   H HH22 . ARG A 1 77  ? -3.467  21.777  30.502 1.00 16.77 ?  43   ARG A HH22 1 
ATOM   429   N N    . LYS A 1 78  ? 1.354   18.150  25.680 1.00 10.60 ?  44   LYS A N    1 
ATOM   430   C CA   . LYS A 1 78  ? 2.512   18.870  26.194 1.00 10.29 ?  44   LYS A CA   1 
ATOM   431   C C    . LYS A 1 78  ? 2.570   20.167  25.414 1.00 10.71 ?  44   LYS A C    1 
ATOM   432   O O    . LYS A 1 78  ? 2.195   20.209  24.230 1.00 11.15 ?  44   LYS A O    1 
ATOM   433   C CB   . LYS A 1 78  ? 3.794   18.063  25.918 1.00 11.91 ?  44   LYS A CB   1 
ATOM   434   C CG   . LYS A 1 78  ? 5.062   18.571  26.660 1.00 12.60 ?  44   LYS A CG   1 
ATOM   435   C CD   . LYS A 1 78  ? 6.327   17.871  26.243 1.00 13.07 ?  44   LYS A CD   1 
ATOM   436   C CE   . LYS A 1 78  ? 7.516   18.490  26.884 1.00 12.30 ?  44   LYS A CE   1 
ATOM   437   N NZ   . LYS A 1 78  ? 8.817   17.903  26.373 1.00 13.23 ?  44   LYS A NZ   1 
ATOM   438   H H    . LYS A 1 78  ? 1.150   18.390  24.880 1.00 12.72 ?  44   LYS A H    1 
ATOM   439   H HA   . LYS A 1 78  ? 2.441   19.041  27.146 1.00 12.35 ?  44   LYS A HA   1 
ATOM   440   H HB2  . LYS A 1 78  ? 3.644   17.145  26.194 1.00 14.29 ?  44   LYS A HB2  1 
ATOM   441   H HB3  . LYS A 1 78  ? 3.979   18.097  24.967 1.00 14.29 ?  44   LYS A HB3  1 
ATOM   442   H HG2  . LYS A 1 78  ? 5.174   19.517  26.477 1.00 15.12 ?  44   LYS A HG2  1 
ATOM   443   H HG3  . LYS A 1 78  ? 4.946   18.429  27.613 1.00 15.12 ?  44   LYS A HG3  1 
ATOM   444   H HD2  . LYS A 1 78  ? 6.284   16.939  26.511 1.00 15.68 ?  44   LYS A HD2  1 
ATOM   445   H HD3  . LYS A 1 78  ? 6.429   17.934  25.281 1.00 15.68 ?  44   LYS A HD3  1 
ATOM   446   H HE2  . LYS A 1 78  ? 7.520   19.441  26.694 1.00 14.76 ?  44   LYS A HE2  1 
ATOM   447   H HE3  . LYS A 1 78  ? 7.474   18.342  27.841 1.00 14.76 ?  44   LYS A HE3  1 
ATOM   448   H HZ1  . LYS A 1 78  ? 8.822   17.021  26.493 1.00 15.88 ?  44   LYS A HZ1  1 
ATOM   449   H HZ2  . LYS A 1 78  ? 8.910   18.076  25.505 1.00 15.88 ?  44   LYS A HZ2  1 
ATOM   450   H HZ3  . LYS A 1 78  ? 9.505   18.258  26.813 1.00 15.88 ?  44   LYS A HZ3  1 
ATOM   451   N N    . ASN A 1 79  ? 2.973   21.292  26.051 1.00 10.55 ?  45   ASN A N    1 
ATOM   452   C CA   . ASN A 1 79  ? 2.892   22.574  25.379 1.00 9.67  ?  45   ASN A CA   1 
ATOM   453   C C    . ASN A 1 79  ? 4.020   22.777  24.374 1.00 11.62 ?  45   ASN A C    1 
ATOM   454   O O    . ASN A 1 79  ? 3.933   23.637  23.490 1.00 11.72 ?  45   ASN A O    1 
ATOM   455   C CB   . ASN A 1 79  ? 2.883   23.734  26.387 1.00 12.29 ?  45   ASN A CB   1 
ATOM   456   C CG   . ASN A 1 79  ? 1.632   23.770  27.210 1.00 11.13 ?  45   ASN A CG   1 
ATOM   457   O OD1  . ASN A 1 79  ? 0.548   24.026  26.680 1.00 13.62 ?  45   ASN A OD1  1 
ATOM   458   N ND2  . ASN A 1 79  ? 1.742   23.411  28.474 1.00 13.06 ?  45   ASN A ND2  1 
ATOM   459   H H    . ASN A 1 79  ? 3.286   21.320  26.852 1.00 12.66 ?  45   ASN A H    1 
ATOM   460   H HA   . ASN A 1 79  ? 2.048   22.608  24.902 1.00 11.60 ?  45   ASN A HA   1 
ATOM   461   H HB2  . ASN A 1 79  ? 3.637   23.636  26.990 1.00 14.75 ?  45   ASN A HB2  1 
ATOM   462   H HB3  . ASN A 1 79  ? 2.951   24.573  25.905 1.00 14.75 ?  45   ASN A HB3  1 
ATOM   463   H HD21 . ASN A 1 79  ? 1.050   23.416  28.984 1.00 15.67 ?  45   ASN A HD21 1 
ATOM   464   H HD22 . ASN A 1 79  ? 2.506   23.171  28.787 1.00 15.67 ?  45   ASN A HD22 1 
ATOM   465   N N    . THR A 1 80  ? 5.095   22.018  24.530 1.00 11.77 ?  46   THR A N    1 
ATOM   466   C CA   . THR A 1 80  ? 6.243   22.031  23.630 1.00 13.15 ?  46   THR A CA   1 
ATOM   467   C C    . THR A 1 80  ? 6.489   20.620  23.136 1.00 13.26 ?  46   THR A C    1 
ATOM   468   O O    . THR A 1 80  ? 5.904   19.656  23.629 1.00 13.43 ?  46   THR A O    1 
ATOM   469   C CB   . THR A 1 80  ? 7.504   22.589  24.340 1.00 12.90 ?  46   THR A CB   1 
ATOM   470   O OG1  . THR A 1 80  ? 7.727   21.814  25.517 1.00 14.59 ?  46   THR A OG1  1 
ATOM   471   C CG2  . THR A 1 80  ? 7.355   24.068  24.661 1.00 14.65 ?  46   THR A CG2  1 
ATOM   472   H H    . THR A 1 80  ? 5.189   21.462  25.178 1.00 14.12 ?  46   THR A H    1 
ATOM   473   H HA   . THR A 1 80  ? 6.056   22.595  22.864 1.00 15.79 ?  46   THR A HA   1 
ATOM   474   H HB   . THR A 1 80  ? 8.280   22.526  23.761 1.00 15.48 ?  46   THR A HB   1 
ATOM   475   H HG1  . THR A 1 80  ? 8.371   22.132  25.953 1.00 17.51 ?  46   THR A HG1  1 
ATOM   476   H HG21 . THR A 1 80  ? 8.087   24.361  25.226 1.00 17.58 ?  46   THR A HG21 1 
ATOM   477   H HG22 . THR A 1 80  ? 7.362   24.588  23.842 1.00 17.58 ?  46   THR A HG22 1 
ATOM   478   H HG23 . THR A 1 80  ? 6.518   24.224  25.126 1.00 17.58 ?  46   THR A HG23 1 
ATOM   479   N N    . ALA A 1 81  ? 7.407   20.495  22.173 1.00 11.56 ?  47   ALA A N    1 
ATOM   480   C CA   . ALA A 1 81  ? 7.696   19.202  21.574 1.00 12.03 ?  47   ALA A CA   1 
ATOM   481   C C    . ALA A 1 81  ? 8.140   18.188  22.619 1.00 11.73 ?  47   ALA A C    1 
ATOM   482   O O    . ALA A 1 81  ? 8.879   18.507  23.563 1.00 12.65 ?  47   ALA A O    1 
ATOM   483   C CB   . ALA A 1 81  ? 8.826   19.294  20.545 1.00 12.90 ?  47   ALA A CB   1 
ATOM   484   H H    . ALA A 1 81  ? 7.872   21.145  21.853 1.00 13.87 ?  47   ALA A H    1 
ATOM   485   H HA   . ALA A 1 81  ? 6.880   18.906  21.142 1.00 14.44 ?  47   ALA A HA   1 
ATOM   486   H HB1  . ALA A 1 81  ? 9.003   18.408  20.191 1.00 15.49 ?  47   ALA A HB1  1 
ATOM   487   H HB2  . ALA A 1 81  ? 8.553   19.888  19.828 1.00 15.49 ?  47   ALA A HB2  1 
ATOM   488   H HB3  . ALA A 1 81  ? 9.620   19.642  20.978 1.00 15.49 ?  47   ALA A HB3  1 
ATOM   489   N N    . TYR A 1 82  ? 7.764   16.942  22.404 1.00 11.97 ?  48   TYR A N    1 
ATOM   490   C CA   . TYR A 1 82  ? 8.270   15.840  23.208 1.00 12.31 ?  48   TYR A CA   1 
ATOM   491   C C    . TYR A 1 82  ? 9.779   15.660  22.969 1.00 13.15 ?  48   TYR A C    1 
ATOM   492   O O    . TYR A 1 82  ? 10.280  15.840  21.857 1.00 14.19 ?  48   TYR A O    1 
ATOM   493   C CB   . TYR A 1 82  ? 7.532   14.528  22.901 1.00 13.43 ?  48   TYR A CB   1 
ATOM   494   C CG   . TYR A 1 82  ? 6.058   14.649  23.250 1.00 10.53 ?  48   TYR A CG   1 
ATOM   495   C CD1  . TYR A 1 82  ? 5.609   14.459  24.546 1.00 12.03 ?  48   TYR A CD1  1 
ATOM   496   C CD2  . TYR A 1 82  ? 5.129   15.005  22.277 1.00 11.64 ?  48   TYR A CD2  1 
ATOM   497   C CE1  . TYR A 1 82  ? 4.256   14.603  24.873 1.00 11.26 ?  48   TYR A CE1  1 
ATOM   498   C CE2  . TYR A 1 82  ? 3.772   15.168  22.585 1.00 11.53 ?  48   TYR A CE2  1 
ATOM   499   C CZ   . TYR A 1 82  ? 3.347   14.973  23.895 1.00 12.18 ?  48   TYR A CZ   1 
ATOM   500   O OH   . TYR A 1 82  ? 2.007   15.150  24.199 1.00 11.96 ?  48   TYR A OH   1 
ATOM   501   H H    . TYR A 1 82  ? 7.211   16.701  21.792 1.00 14.37 ?  48   TYR A H    1 
ATOM   502   H HA   . TYR A 1 82  ? 8.119   16.040  24.145 1.00 14.77 ?  48   TYR A HA   1 
ATOM   503   H HB2  . TYR A 1 82  ? 7.611   14.326  21.956 1.00 16.12 ?  48   TYR A HB2  1 
ATOM   504   H HB3  . TYR A 1 82  ? 7.917   13.810  23.427 1.00 16.12 ?  48   TYR A HB3  1 
ATOM   505   H HD1  . TYR A 1 82  ? 6.217   14.233  25.212 1.00 14.44 ?  48   TYR A HD1  1 
ATOM   506   H HD2  . TYR A 1 82  ? 5.415   15.139  21.402 1.00 13.97 ?  48   TYR A HD2  1 
ATOM   507   H HE1  . TYR A 1 82  ? 3.968   14.450  25.743 1.00 13.51 ?  48   TYR A HE1  1 
ATOM   508   H HE2  . TYR A 1 82  ? 3.163   15.404  21.923 1.00 13.83 ?  48   TYR A HE2  1 
ATOM   509   H HH   . TYR A 1 82  ? 1.588   15.399  23.515 1.00 14.35 ?  48   TYR A HH   1 
ATOM   510   N N    . THR A 1 83  ? 10.491  15.278  24.023 1.00 13.20 ?  49   THR A N    1 
ATOM   511   C CA   . THR A 1 83  ? 11.891  14.887  23.848 1.00 13.70 ?  49   THR A CA   1 
ATOM   512   C C    . THR A 1 83  ? 11.949  13.540  23.139 1.00 14.22 ?  49   THR A C    1 
ATOM   513   O O    . THR A 1 83  ? 10.960  12.813  23.041 1.00 13.63 ?  49   THR A O    1 
ATOM   514   C CB   . THR A 1 83  ? 12.609  14.724  25.198 1.00 14.08 ?  49   THR A CB   1 
ATOM   515   O OG1  . THR A 1 83  ? 12.030  13.608  25.870 1.00 13.87 ?  49   THR A OG1  1 
ATOM   516   C CG2  . THR A 1 83  ? 12.541  16.003  26.046 1.00 14.37 ?  49   THR A CG2  1 
ATOM   517   H H    . THR A 1 83  ? 10.198  15.237  24.831 1.00 15.84 ?  49   THR A H    1 
ATOM   518   H HA   . THR A 1 83  ? 12.338  15.578  23.335 1.00 16.44 ?  49   THR A HA   1 
ATOM   519   H HB   . THR A 1 83  ? 13.556  14.564  25.063 1.00 16.90 ?  49   THR A HB   1 
ATOM   520   H HG1  . THR A 1 83  ? 12.103  13.704  26.701 1.00 16.65 ?  49   THR A HG1  1 
ATOM   521   H HG21 . THR A 1 83  ? 13.057  15.890  26.859 1.00 17.24 ?  49   THR A HG21 1 
ATOM   522   H HG22 . THR A 1 83  ? 12.900  16.752  25.546 1.00 17.24 ?  49   THR A HG22 1 
ATOM   523   H HG23 . THR A 1 83  ? 11.620  16.195  26.283 1.00 17.24 ?  49   THR A HG23 1 
ATOM   524   N N    . ASP A 1 84  ? 13.156  13.143  22.698 1.00 14.69 ?  50   ASP A N    1 
ATOM   525   C CA   . ASP A 1 84  ? 13.293  11.821  22.094 1.00 15.36 ?  50   ASP A CA   1 
ATOM   526   C C    . ASP A 1 84  ? 12.875  10.731  23.070 1.00 14.93 ?  50   ASP A C    1 
ATOM   527   O O    . ASP A 1 84  ? 12.199  9.769   22.685 1.00 15.89 ?  50   ASP A O    1 
ATOM   528   C CB   . ASP A 1 84  ? 14.754  11.619  21.666 1.00 17.17 ?  50   ASP A CB   1 
ATOM   529   C CG   . ASP A 1 84  ? 15.179  12.511  20.505 1.00 25.33 ?  50   ASP A CG   1 
ATOM   530   O OD1  . ASP A 1 84  ? 14.354  13.171  19.851 1.00 26.06 ?  50   ASP A OD1  1 
ATOM   531   O OD2  . ASP A 1 84  ? 16.420  12.592  20.265 1.00 34.76 ?  50   ASP A OD2  1 
ATOM   532   H H    . ASP A 1 84  ? 13.879  13.607  22.738 1.00 17.63 ?  50   ASP A H    1 
ATOM   533   H HA   . ASP A 1 84  ? 12.724  11.758  21.312 1.00 18.43 ?  50   ASP A HA   1 
ATOM   534   H HB2  . ASP A 1 84  ? 15.331  11.818  22.420 1.00 20.60 ?  50   ASP A HB2  1 
ATOM   535   H HB3  . ASP A 1 84  ? 14.875  10.696  21.391 1.00 20.60 ?  50   ASP A HB3  1 
ATOM   536   N N    . GLU A 1 85  ? 13.288  10.842  24.331 1.00 15.50 ?  51   GLU A N    1 
ATOM   537   C CA   . GLU A 1 85  ? 12.924  9.862   25.343 1.00 16.81 ?  51   GLU A CA   1 
ATOM   538   C C    . GLU A 1 85  ? 11.404  9.788   25.480 1.00 13.82 ?  51   GLU A C    1 
ATOM   539   O O    . GLU A 1 85  ? 10.831  8.711   25.610 1.00 15.01 ?  51   GLU A O    1 
ATOM   540   C CB   . GLU A 1 85  ? 13.561  10.192  26.700 1.00 18.17 ?  51   GLU A CB   1 
ATOM   541   C CG   . GLU A 1 85  ? 13.062  9.311   27.854 1.00 21.15 ?  51   GLU A CG   1 
ATOM   542   C CD   . GLU A 1 85  ? 13.418  9.754   29.293 1.00 33.95 ?  51   GLU A CD   1 
ATOM   543   O OE1  . GLU A 1 85  ? 13.633  10.949  29.573 1.00 23.53 ?  51   GLU A OE1  1 
ATOM   544   O OE2  . GLU A 1 85  ? 13.491  8.846   30.165 1.00 34.43 ?  51   GLU A OE2  1 
ATOM   545   H H    . GLU A 1 85  ? 13.783  11.480  24.627 1.00 18.60 ?  51   GLU A H    1 
ATOM   546   H HA   . GLU A 1 85  ? 13.270  8.997   25.071 1.00 20.18 ?  51   GLU A HA   1 
ATOM   547   H HB2  . GLU A 1 85  ? 14.521  10.071  26.631 1.00 21.80 ?  51   GLU A HB2  1 
ATOM   548   H HB3  . GLU A 1 85  ? 13.357  11.113  26.923 1.00 21.80 ?  51   GLU A HB3  1 
ATOM   549   H HG2  . GLU A 1 85  ? 12.094  9.274   27.804 1.00 25.38 ?  51   GLU A HG2  1 
ATOM   550   H HG3  . GLU A 1 85  ? 13.435  8.424   27.734 1.00 25.38 ?  51   GLU A HG3  1 
ATOM   551   N N    . GLU A 1 86  ? 10.738  10.962  25.474 1.00 13.85 ?  52   GLU A N    1 
ATOM   552   C CA   . GLU A 1 86  ? 9.275   10.972  25.562 1.00 14.62 ?  52   GLU A CA   1 
ATOM   553   C C    . GLU A 1 86  ? 8.620   10.325  24.344 1.00 13.48 ?  52   GLU A C    1 
ATOM   554   O O    . GLU A 1 86  ? 7.607   9.628   24.491 1.00 13.75 ?  52   GLU A O    1 
ATOM   555   C CB   . GLU A 1 86  ? 8.821   12.408  25.760 1.00 13.82 ?  52   GLU A CB   1 
ATOM   556   C CG   . GLU A 1 86  ? 9.081   12.933  27.158 1.00 13.88 ?  52   GLU A CG   1 
ATOM   557   C CD   . GLU A 1 86  ? 8.841   14.403  27.334 1.00 13.95 ?  52   GLU A CD   1 
ATOM   558   O OE1  . GLU A 1 86  ? 8.933   15.177  26.372 1.00 13.07 ?  52   GLU A OE1  1 
ATOM   559   O OE2  . GLU A 1 86  ? 8.599   14.771  28.526 1.00 18.37 ?  52   GLU A OE2  1 
ATOM   560   H H    . GLU A 1 86  ? 11.104  11.739  25.420 1.00 16.62 ?  52   GLU A H    1 
ATOM   561   H HA   . GLU A 1 86  ? 8.986   10.448  26.325 1.00 17.55 ?  52   GLU A HA   1 
ATOM   562   H HB2  . GLU A 1 86  ? 9.298   12.977  25.135 1.00 16.58 ?  52   GLU A HB2  1 
ATOM   563   H HB3  . GLU A 1 86  ? 7.867   12.461  25.594 1.00 16.58 ?  52   GLU A HB3  1 
ATOM   564   H HG2  . GLU A 1 86  ? 8.496   12.467  27.776 1.00 16.66 ?  52   GLU A HG2  1 
ATOM   565   H HG3  . GLU A 1 86  ? 10.008  12.760  27.385 1.00 16.66 ?  52   GLU A HG3  1 
ATOM   566   N N    . ILE A 1 87  ? 9.147   10.576  23.146 1.00 13.25 ?  53   ILE A N    1 
ATOM   567   C CA   . ILE A 1 87  ? 8.633   9.885   21.956 1.00 13.55 ?  53   ILE A CA   1 
ATOM   568   C C    . ILE A 1 87  ? 8.771   8.378   22.092 1.00 15.05 ?  53   ILE A C    1 
ATOM   569   O O    . ILE A 1 87  ? 7.860   7.635   21.723 1.00 15.54 ?  53   ILE A O    1 
ATOM   570   C CB   . ILE A 1 87  ? 9.291   10.441  20.681 1.00 14.12 ?  53   ILE A CB   1 
ATOM   571   C CG1  . ILE A 1 87  ? 8.891   11.903  20.435 1.00 13.62 ?  53   ILE A CG1  1 
ATOM   572   C CG2  . ILE A 1 87  ? 8.985   9.526   19.499 1.00 14.93 ?  53   ILE A CG2  1 
ATOM   573   C CD1  . ILE A 1 87  ? 7.414   12.143  20.180 1.00 13.95 ?  53   ILE A CD1  1 
ATOM   574   H H    . ILE A 1 87  ? 9.788   11.129  22.994 1.00 15.90 ?  53   ILE A H    1 
ATOM   575   H HA   . ILE A 1 87  ? 7.683   10.067  21.885 1.00 16.26 ?  53   ILE A HA   1 
ATOM   576   H HB   . ILE A 1 87  ? 10.254  10.450  20.800 1.00 16.94 ?  53   ILE A HB   1 
ATOM   577   H HG12 . ILE A 1 87  ? 9.137   12.423  21.216 1.00 16.34 ?  53   ILE A HG12 1 
ATOM   578   H HG13 . ILE A 1 87  ? 9.374   12.225  19.658 1.00 16.34 ?  53   ILE A HG13 1 
ATOM   579   H HG21 . ILE A 1 87  ? 9.247   9.971   18.678 1.00 17.92 ?  53   ILE A HG21 1 
ATOM   580   H HG22 . ILE A 1 87  ? 9.484   8.700   19.601 1.00 17.92 ?  53   ILE A HG22 1 
ATOM   581   H HG23 . ILE A 1 87  ? 8.034   9.337   19.483 1.00 17.92 ?  53   ILE A HG23 1 
ATOM   582   H HD11 . ILE A 1 87  ? 7.293   13.049  19.857 1.00 16.73 ?  53   ILE A HD11 1 
ATOM   583   H HD12 . ILE A 1 87  ? 7.102   11.510  19.515 1.00 16.73 ?  53   ILE A HD12 1 
ATOM   584   H HD13 . ILE A 1 87  ? 6.927   12.019  21.009 1.00 16.73 ?  53   ILE A HD13 1 
ATOM   585   N N    . ASN A 1 88  ? 9.917   7.898   22.580 1.00 14.76 ?  54   ASN A N    1 
ATOM   586   C CA   . ASN A 1 88  ? 10.084  6.465   22.766 1.00 15.83 ?  54   ASN A CA   1 
ATOM   587   C C    . ASN A 1 88  ? 9.047   5.930   23.742 1.00 17.07 ?  54   ASN A C    1 
ATOM   588   O O    . ASN A 1 88  ? 8.456   4.866   23.505 1.00 16.54 ?  54   ASN A O    1 
ATOM   589   C CB   . ASN A 1 88  ? 11.487  6.145   23.257 1.00 16.30 ?  54   ASN A CB   1 
ATOM   590   C CG   . ASN A 1 88  ? 12.552  6.427   22.228 1.00 20.69 ?  54   ASN A CG   1 
ATOM   591   O OD1  . ASN A 1 88  ? 12.289  6.561   21.037 1.00 27.33 ?  54   ASN A OD1  1 
ATOM   592   N ND2  . ASN A 1 88  ? 13.786  6.545   22.707 1.00 24.40 ?  54   ASN A ND2  1 
ATOM   593   H H    . ASN A 1 88  ? 10.597  8.374   22.805 1.00 17.71 ?  54   ASN A H    1 
ATOM   594   H HA   . ASN A 1 88  ? 9.967   6.023   21.911 1.00 19.00 ?  54   ASN A HA   1 
ATOM   595   H HB2  . ASN A 1 88  ? 11.677  6.686   24.039 1.00 19.57 ?  54   ASN A HB2  1 
ATOM   596   H HB3  . ASN A 1 88  ? 11.534  5.204   23.484 1.00 19.57 ?  54   ASN A HB3  1 
ATOM   597   H HD21 . ASN A 1 88  ? 14.441  6.706   22.174 1.00 29.28 ?  54   ASN A HD21 1 
ATOM   598   H HD22 . ASN A 1 88  ? 13.929  6.460   23.551 1.00 29.28 ?  54   ASN A HD22 1 
ATOM   599   N N    . TYR A 1 89  ? 8.766   6.676   24.816 1.00 15.72 ?  55   TYR A N    1 
ATOM   600   C CA   . TYR A 1 89  ? 7.730   6.253   25.758 1.00 14.16 ?  55   TYR A CA   1 
ATOM   601   C C    . TYR A 1 89  ? 6.364   6.190   25.083 1.00 13.36 ?  55   TYR A C    1 
ATOM   602   O O    . TYR A 1 89  ? 5.651   5.183   25.180 1.00 14.85 ?  55   TYR A O    1 
ATOM   603   C CB   . TYR A 1 89  ? 7.730   7.241   26.916 1.00 16.27 ?  55   TYR A CB   1 
ATOM   604   C CG   . TYR A 1 89  ? 6.760   6.992   28.032 1.00 14.02 ?  55   TYR A CG   1 
ATOM   605   C CD1  . TYR A 1 89  ? 6.911   5.911   28.899 1.00 15.61 ?  55   TYR A CD1  1 
ATOM   606   C CD2  . TYR A 1 89  ? 5.692   7.854   28.261 1.00 14.26 ?  55   TYR A CD2  1 
ATOM   607   C CE1  . TYR A 1 89  ? 6.042   5.712   29.936 1.00 16.27 ?  55   TYR A CE1  1 
ATOM   608   C CE2  . TYR A 1 89  ? 4.839   7.662   29.297 1.00 14.34 ?  55   TYR A CE2  1 
ATOM   609   C CZ   . TYR A 1 89  ? 4.992   6.599   30.133 1.00 15.66 ?  55   TYR A CZ   1 
ATOM   610   O OH   . TYR A 1 89  ? 4.119   6.422   31.186 1.00 18.12 ?  55   TYR A OH   1 
ATOM   611   H H    . TYR A 1 89  ? 9.154   7.417   25.017 1.00 18.86 ?  55   TYR A H    1 
ATOM   612   H HA   . TYR A 1 89  ? 7.918   5.362   26.094 1.00 16.99 ?  55   TYR A HA   1 
ATOM   613   H HB2  . TYR A 1 89  ? 8.616   7.240   27.310 1.00 19.52 ?  55   TYR A HB2  1 
ATOM   614   H HB3  . TYR A 1 89  ? 7.527   8.120   26.559 1.00 19.52 ?  55   TYR A HB3  1 
ATOM   615   H HD1  . TYR A 1 89  ? 7.614   5.316   28.771 1.00 18.74 ?  55   TYR A HD1  1 
ATOM   616   H HD2  . TYR A 1 89  ? 5.559   8.576   27.691 1.00 17.12 ?  55   TYR A HD2  1 
ATOM   617   H HE1  . TYR A 1 89  ? 6.154   4.986   30.507 1.00 19.52 ?  55   TYR A HE1  1 
ATOM   618   H HE2  . TYR A 1 89  ? 4.143   8.262   29.437 1.00 17.21 ?  55   TYR A HE2  1 
ATOM   619   H HH   . TYR A 1 89  ? 4.485   5.968   31.790 1.00 21.74 ?  55   TYR A HH   1 
ATOM   620   N N    . LEU A 1 90  ? 5.975   7.257   24.380 1.00 13.62 ?  56   LEU A N    1 
ATOM   621   C CA   . LEU A 1 90  ? 4.683   7.248   23.700 1.00 12.99 ?  56   LEU A CA   1 
ATOM   622   C C    . LEU A 1 90  ? 4.571   6.062   22.745 1.00 14.15 ?  56   LEU A C    1 
ATOM   623   O O    . LEU A 1 90  ? 3.532   5.388   22.685 1.00 14.31 ?  56   LEU A O    1 
ATOM   624   C CB   . LEU A 1 90  ? 4.498   8.551   22.937 1.00 15.40 ?  56   LEU A CB   1 
ATOM   625   C CG   . LEU A 1 90  ? 4.269   9.796   23.782 1.00 13.26 ?  56   LEU A CG   1 
ATOM   626   C CD1  . LEU A 1 90  ? 4.058   11.019  22.924 1.00 15.57 ?  56   LEU A CD1  1 
ATOM   627   C CD2  . LEU A 1 90  ? 3.071   9.548   24.693 1.00 15.91 ?  56   LEU A CD2  1 
ATOM   628   H H    . LEU A 1 90  ? 6.430   7.981   24.284 1.00 16.34 ?  56   LEU A H    1 
ATOM   629   H HA   . LEU A 1 90  ? 3.979   7.172   24.363 1.00 15.59 ?  56   LEU A HA   1 
ATOM   630   H HB2  . LEU A 1 90  ? 5.296   8.706   22.407 1.00 18.48 ?  56   LEU A HB2  1 
ATOM   631   H HB3  . LEU A 1 90  ? 3.728   8.453   22.355 1.00 18.48 ?  56   LEU A HB3  1 
ATOM   632   H HG   . LEU A 1 90  ? 5.053   9.977   24.323 1.00 15.91 ?  56   LEU A HG   1 
ATOM   633   H HD11 . LEU A 1 90  ? 3.964   11.796  23.498 1.00 18.69 ?  56   LEU A HD11 1 
ATOM   634   H HD12 . LEU A 1 90  ? 4.825   11.131  22.340 1.00 18.69 ?  56   LEU A HD12 1 
ATOM   635   H HD13 . LEU A 1 90  ? 3.254   10.900  22.395 1.00 18.69 ?  56   LEU A HD13 1 
ATOM   636   H HD21 . LEU A 1 90  ? 2.819   10.382  25.118 1.00 19.09 ?  56   LEU A HD21 1 
ATOM   637   H HD22 . LEU A 1 90  ? 2.333   9.212   24.160 1.00 19.09 ?  56   LEU A HD22 1 
ATOM   638   H HD23 . LEU A 1 90  ? 3.316   8.894   25.366 1.00 19.09 ?  56   LEU A HD23 1 
ATOM   639   N N    . ALA A 1 91  ? 5.625   5.798   21.966 1.00 14.44 ?  57   ALA A N    1 
ATOM   640   C CA   . ALA A 1 91  ? 5.596   4.742   20.961 1.00 14.89 ?  57   ALA A CA   1 
ATOM   641   C C    . ALA A 1 91  ? 5.488   3.352   21.546 1.00 15.77 ?  57   ALA A C    1 
ATOM   642   O O    . ALA A 1 91  ? 5.144   2.422   20.796 1.00 16.97 ?  57   ALA A O    1 
ATOM   643   C CB   . ALA A 1 91  ? 6.821   4.841   20.059 1.00 17.95 ?  57   ALA A CB   1 
ATOM   644   H H    . ALA A 1 91  ? 6.373   6.221   22.003 1.00 17.33 ?  57   ALA A H    1 
ATOM   645   H HA   . ALA A 1 91  ? 4.807   4.876   20.413 1.00 17.86 ?  57   ALA A HA   1 
ATOM   646   H HB1  . ALA A 1 91  ? 6.797   4.118   19.413 1.00 21.54 ?  57   ALA A HB1  1 
ATOM   647   H HB2  . ALA A 1 91  ? 6.806   5.695   19.599 1.00 21.54 ?  57   ALA A HB2  1 
ATOM   648   H HB3  . ALA A 1 91  ? 7.620   4.772   20.603 1.00 21.54 ?  57   ALA A HB3  1 
ATOM   649   N N    . SER A 1 92  ? 5.740   3.190   22.849 1.00 13.70 ?  58   SER A N    1 
ATOM   650   C CA   . SER A 1 92  ? 5.580   1.909   23.507 1.00 13.63 ?  58   SER A CA   1 
ATOM   651   C C    . SER A 1 92  ? 4.134   1.565   23.838 1.00 16.26 ?  58   SER A C    1 
ATOM   652   O O    . SER A 1 92  ? 3.867   0.426   24.264 1.00 17.50 ?  58   SER A O    1 
ATOM   653   C CB   . SER A 1 92  ? 6.424   1.864   24.783 1.00 14.95 ?  58   SER A CB   1 
ATOM   654   O OG   . SER A 1 92  ? 5.845   2.602   25.870 1.00 15.75 ?  58   SER A OG   1 
ATOM   655   H H    . SER A 1 92  ? 6.008   3.818   23.372 1.00 16.44 ?  58   SER A H    1 
ATOM   656   H HA   . SER A 1 92  ? 5.906   1.221   22.906 1.00 16.36 ?  58   SER A HA   1 
ATOM   657   H HB2  . SER A 1 92  ? 6.517   0.938   25.056 1.00 17.94 ?  58   SER A HB2  1 
ATOM   658   H HB3  . SER A 1 92  ? 7.296   2.241   24.587 1.00 17.94 ?  58   SER A HB3  1 
ATOM   659   H HG   . SER A 1 92  ? 6.032   3.418   25.795 1.00 18.90 ?  58   SER A HG   1 
ATOM   660   N N    . PHE A 1 93  ? 3.189   2.505   23.690 1.00 13.25 ?  59   PHE A N    1 
ATOM   661   C CA   . PHE A 1 93  ? 1.785   2.237   23.986 1.00 12.79 ?  59   PHE A CA   1 
ATOM   662   C C    . PHE A 1 93  ? 1.057   1.811   22.716 1.00 14.36 ?  59   PHE A C    1 
ATOM   663   O O    . PHE A 1 93  ? 1.329   2.350   21.624 1.00 15.07 ?  59   PHE A O    1 
ATOM   664   C CB   . PHE A 1 93  ? 1.094   3.513   24.506 1.00 13.11 ?  59   PHE A CB   1 
ATOM   665   C CG   . PHE A 1 93  ? 1.539   3.884   25.876 1.00 13.58 ?  59   PHE A CG   1 
ATOM   666   C CD1  . PHE A 1 93  ? 2.699   4.648   26.069 1.00 13.19 ?  59   PHE A CD1  1 
ATOM   667   C CD2  . PHE A 1 93  ? 0.860   3.427   27.003 1.00 13.62 ?  59   PHE A CD2  1 
ATOM   668   C CE1  . PHE A 1 93  ? 3.147   4.936   27.327 1.00 13.94 ?  59   PHE A CE1  1 
ATOM   669   C CE2  . PHE A 1 93  ? 1.298   3.730   28.262 1.00 14.43 ?  59   PHE A CE2  1 
ATOM   670   C CZ   . PHE A 1 93  ? 2.455   4.477   28.437 1.00 14.95 ?  59   PHE A CZ   1 
ATOM   671   H H    . PHE A 1 93  ? 3.340   3.307   23.419 1.00 15.90 ?  59   PHE A H    1 
ATOM   672   H HA   . PHE A 1 93  ? 1.726   1.535   24.653 1.00 15.35 ?  59   PHE A HA   1 
ATOM   673   H HB2  . PHE A 1 93  ? 1.302   4.251   23.912 1.00 15.73 ?  59   PHE A HB2  1 
ATOM   674   H HB3  . PHE A 1 93  ? 0.135   3.366   24.530 1.00 15.73 ?  59   PHE A HB3  1 
ATOM   675   H HD1  . PHE A 1 93  ? 3.170   4.962   25.331 1.00 15.83 ?  59   PHE A HD1  1 
ATOM   676   H HD2  . PHE A 1 93  ? 0.096   2.907   26.897 1.00 16.34 ?  59   PHE A HD2  1 
ATOM   677   H HE1  . PHE A 1 93  ? 3.919   5.442   27.439 1.00 16.73 ?  59   PHE A HE1  1 
ATOM   678   H HE2  . PHE A 1 93  ? 0.819   3.435   29.003 1.00 17.32 ?  59   PHE A HE2  1 
ATOM   679   H HZ   . PHE A 1 93  ? 2.765   4.668   29.293 1.00 17.94 ?  59   PHE A HZ   1 
ATOM   680   N N    . PRO A 1 94  ? 0.138   0.856   22.805 1.00 11.97 ?  60   PRO A N    1 
ATOM   681   C CA   . PRO A 1 94  ? -0.546  0.414   21.590 1.00 13.76 ?  60   PRO A CA   1 
ATOM   682   C C    . PRO A 1 94  ? -1.550  1.402   21.036 1.00 13.55 ?  60   PRO A C    1 
ATOM   683   O O    . PRO A 1 94  ? -1.820  1.388   19.833 1.00 13.29 ?  60   PRO A O    1 
ATOM   684   C CB   . PRO A 1 94  ? -1.223  -0.897  22.014 1.00 13.66 ?  60   PRO A CB   1 
ATOM   685   C CG   . PRO A 1 94  ? -1.351  -0.807  23.483 1.00 16.03 ?  60   PRO A CG   1 
ATOM   686   C CD   . PRO A 1 94  ? -0.121  -0.051  23.945 1.00 13.28 ?  60   PRO A CD   1 
ATOM   687   H HA   . PRO A 1 94  ? 0.114   0.226   20.904 1.00 16.52 ?  60   PRO A HA   1 
ATOM   688   H HB2  . PRO A 1 94  ? -2.094  -0.969  21.594 1.00 16.40 ?  60   PRO A HB2  1 
ATOM   689   H HB3  . PRO A 1 94  ? -0.669  -1.652  21.760 1.00 16.40 ?  60   PRO A HB3  1 
ATOM   690   H HG2  . PRO A 1 94  ? -2.160  -0.325  23.715 1.00 19.24 ?  60   PRO A HG2  1 
ATOM   691   H HG3  . PRO A 1 94  ? -1.374  -1.697  23.867 1.00 19.24 ?  60   PRO A HG3  1 
ATOM   692   H HD2  . PRO A 1 94  ? -0.303  0.449   24.756 1.00 15.94 ?  60   PRO A HD2  1 
ATOM   693   H HD3  . PRO A 1 94  ? 0.626   -0.654  24.088 1.00 15.94 ?  60   PRO A HD3  1 
ATOM   694   N N    . LEU A 1 95  ? -2.078  2.291   21.878 1.00 13.23 ?  61   LEU A N    1 
ATOM   695   C CA   . LEU A 1 95  ? -3.117  3.226   21.455 1.00 12.99 ?  61   LEU A CA   1 
ATOM   696   C C    . LEU A 1 95  ? -2.871  4.526   22.215 1.00 13.17 ?  61   LEU A C    1 
ATOM   697   O O    . LEU A 1 95  ? -2.775  4.516   23.447 1.00 12.61 ?  61   LEU A O    1 
ATOM   698   C CB   . LEU A 1 95  ? -4.485  2.675   21.787 1.00 12.57 ?  61   LEU A CB   1 
ATOM   699   C CG   . LEU A 1 95  ? -5.710  3.494   21.379 1.00 12.25 ?  61   LEU A CG   1 
ATOM   700   C CD1  . LEU A 1 95  ? -5.696  3.798   19.904 1.00 13.04 ?  61   LEU A CD1  1 
ATOM   701   C CD2  . LEU A 1 95  ? -6.975  2.779   21.805 1.00 14.80 ?  61   LEU A CD2  1 
ATOM   702   H H    . LEU A 1 95  ? -1.850  2.372   22.704 1.00 15.87 ?  61   LEU A H    1 
ATOM   703   H HA   . LEU A 1 95  ? -3.079  3.394   20.500 1.00 15.59 ?  61   LEU A HA   1 
ATOM   704   H HB2  . LEU A 1 95  ? -4.569  1.813   21.350 1.00 15.09 ?  61   LEU A HB2  1 
ATOM   705   H HB3  . LEU A 1 95  ? -4.533  2.564   22.749 1.00 15.09 ?  61   LEU A HB3  1 
ATOM   706   H HG   . LEU A 1 95  ? -5.692  4.352   21.831 1.00 14.70 ?  61   LEU A HG   1 
ATOM   707   H HD11 . LEU A 1 95  ? -6.524  4.244   19.666 1.00 15.65 ?  61   LEU A HD11 1 
ATOM   708   H HD12 . LEU A 1 95  ? -4.941  4.374   19.707 1.00 15.65 ?  61   LEU A HD12 1 
ATOM   709   H HD13 . LEU A 1 95  ? -5.615  2.966   19.412 1.00 15.65 ?  61   LEU A HD13 1 
ATOM   710   H HD21 . LEU A 1 95  ? -7.742  3.320   21.560 1.00 17.76 ?  61   LEU A HD21 1 
ATOM   711   H HD22 . LEU A 1 95  ? -7.019  1.920   21.357 1.00 17.76 ?  61   LEU A HD22 1 
ATOM   712   H HD23 . LEU A 1 95  ? -6.956  2.650   22.766 1.00 17.76 ?  61   LEU A HD23 1 
ATOM   713   N N    . ILE A 1 96  ? -2.755  5.617   21.471 1.00 12.47 ?  62   ILE A N    1 
ATOM   714   C CA   . ILE A 1 96  ? -2.407  6.941   21.996 1.00 12.19 ?  62   ILE A CA   1 
ATOM   715   C C    . ILE A 1 96  ? -3.401  7.948   21.464 1.00 12.42 ?  62   ILE A C    1 
ATOM   716   O O    . ILE A 1 96  ? -3.573  8.054   20.251 1.00 13.93 ?  62   ILE A O    1 
ATOM   717   C CB   . ILE A 1 96  ? -1.001  7.360   21.535 1.00 12.45 ?  62   ILE A CB   1 
ATOM   718   C CG1  . ILE A 1 96  ? 0.059   6.349   21.971 1.00 13.40 ?  62   ILE A CG1  1 
ATOM   719   C CG2  . ILE A 1 96  ? -0.668  8.714   22.115 1.00 14.17 ?  62   ILE A CG2  1 
ATOM   720   C CD1  . ILE A 1 96  ? 0.892   5.910   20.811 1.00 16.25 ?  62   ILE A CD1  1 
ATOM   721   H H    . ILE A 1 96  ? -2.878  5.621   20.620 1.00 14.96 ?  62   ILE A H    1 
ATOM   722   H HA   . ILE A 1 96  ? -2.455  6.921   22.965 1.00 14.63 ?  62   ILE A HA   1 
ATOM   723   H HB   . ILE A 1 96  ? -1.003  7.395   20.565 1.00 14.94 ?  62   ILE A HB   1 
ATOM   724   H HG12 . ILE A 1 96  ? 0.641   6.757   22.631 1.00 16.08 ?  62   ILE A HG12 1 
ATOM   725   H HG13 . ILE A 1 96  ? -0.376  5.569   22.350 1.00 16.08 ?  62   ILE A HG13 1 
ATOM   726   H HG21 . ILE A 1 96  ? 0.262   8.917   21.929 1.00 17.01 ?  62   ILE A HG21 1 
ATOM   727   H HG22 . ILE A 1 96  ? -1.240  9.382   21.707 1.00 17.01 ?  62   ILE A HG22 1 
ATOM   728   H HG23 . ILE A 1 96  ? -0.817  8.692   23.073 1.00 17.01 ?  62   ILE A HG23 1 
ATOM   729   H HD11 . ILE A 1 96  ? 1.602   5.331   21.133 1.00 19.50 ?  62   ILE A HD11 1 
ATOM   730   H HD12 . ILE A 1 96  ? 0.331   5.427   20.184 1.00 19.50 ?  62   ILE A HD12 1 
ATOM   731   H HD13 . ILE A 1 96  ? 1.273   6.692   20.382 1.00 19.50 ?  62   ILE A HD13 1 
ATOM   732   N N    . THR A 1 97  ? -4.014  8.724   22.348 1.00 11.16 ?  63   THR A N    1 
ATOM   733   C CA   . THR A 1 97  ? -4.766  9.914   21.935 1.00 11.60 ?  63   THR A CA   1 
ATOM   734   C C    . THR A 1 97  ? -3.937  11.156  22.187 1.00 10.27 ?  63   THR A C    1 
ATOM   735   O O    . THR A 1 97  ? -3.456  11.379  23.315 1.00 11.07 ?  63   THR A O    1 
ATOM   736   C CB   . THR A 1 97  ? -6.095  10.047  22.680 1.00 10.92 ?  63   THR A CB   1 
ATOM   737   O OG1  . THR A 1 97  ? -6.917  8.933   22.257 1.00 11.59 ?  63   THR A OG1  1 
ATOM   738   C CG2  . THR A 1 97  ? -6.798  11.334  22.362 1.00 11.37 ?  63   THR A CG2  1 
ATOM   739   H H    . THR A 1 97  ? -4.012  8.587   23.197 1.00 13.40 ?  63   THR A H    1 
ATOM   740   H HA   . THR A 1 97  ? -4.954  9.833   20.987 1.00 13.92 ?  63   THR A HA   1 
ATOM   741   H HB   . THR A 1 97  ? -5.947  10.048  23.638 1.00 13.10 ?  63   THR A HB   1 
ATOM   742   H HG1  . THR A 1 97  ? -6.861  8.307   22.814 1.00 13.91 ?  63   THR A HG1  1 
ATOM   743   H HG21 . THR A 1 97  ? -7.690  11.327  22.743 1.00 13.64 ?  63   THR A HG21 1 
ATOM   744   H HG22 . THR A 1 97  ? -6.304  12.082  22.731 1.00 13.64 ?  63   THR A HG22 1 
ATOM   745   H HG23 . THR A 1 97  ? -6.868  11.445  21.401 1.00 13.64 ?  63   THR A HG23 1 
ATOM   746   N N    . LEU A 1 98  ? -3.790  11.960  21.141 1.00 10.85 ?  64   LEU A N    1 
ATOM   747   C CA   . LEU A 1 98  ? -3.166  13.276  21.237 1.00 11.39 ?  64   LEU A CA   1 
ATOM   748   C C    . LEU A 1 98  ? -4.263  14.303  21.493 1.00 10.27 ?  64   LEU A C    1 
ATOM   749   O O    . LEU A 1 98  ? -5.129  14.535  20.649 1.00 11.46 ?  64   LEU A O    1 
ATOM   750   C CB   . LEU A 1 98  ? -2.393  13.616  19.968 1.00 10.62 ?  64   LEU A CB   1 
ATOM   751   C CG   . LEU A 1 98  ? -1.222  12.655  19.685 1.00 11.24 ?  64   LEU A CG   1 
ATOM   752   C CD1  . LEU A 1 98  ? -0.527  13.061  18.421 1.00 12.00 ?  64   LEU A CD1  1 
ATOM   753   C CD2  . LEU A 1 98  ? -0.227  12.569  20.806 1.00 12.04 ?  64   LEU A CD2  1 
ATOM   754   H H    . LEU A 1 98  ? -4.050  11.763  20.345 1.00 13.03 ?  64   LEU A H    1 
ATOM   755   H HA   . LEU A 1 98  ? -2.541  13.279  21.979 1.00 13.67 ?  64   LEU A HA   1 
ATOM   756   H HB2  . LEU A 1 98  ? -3.001  13.576  19.212 1.00 12.74 ?  64   LEU A HB2  1 
ATOM   757   H HB3  . LEU A 1 98  ? -2.030  14.511  20.054 1.00 12.74 ?  64   LEU A HB3  1 
ATOM   758   H HG   . LEU A 1 98  ? -1.599  11.766  19.591 1.00 13.49 ?  64   LEU A HG   1 
ATOM   759   H HD11 . LEU A 1 98  ? 0.186   12.430  18.235 1.00 14.41 ?  64   LEU A HD11 1 
ATOM   760   H HD12 . LEU A 1 98  ? -1.169  13.060  17.693 1.00 14.41 ?  64   LEU A HD12 1 
ATOM   761   H HD13 . LEU A 1 98  ? -0.158  13.951  18.535 1.00 14.41 ?  64   LEU A HD13 1 
ATOM   762   H HD21 . LEU A 1 98  ? 0.549   12.073  20.503 1.00 14.45 ?  64   LEU A HD21 1 
ATOM   763   H HD22 . LEU A 1 98  ? 0.034   13.467  21.066 1.00 14.45 ?  64   LEU A HD22 1 
ATOM   764   H HD23 . LEU A 1 98  ? -0.638  12.114  21.558 1.00 14.45 ?  64   LEU A HD23 1 
ATOM   765   N N    . GLU A 1 99  ? -4.239  14.877  22.705 1.00 10.03 ?  65   GLU A N    1 
ATOM   766   C CA   . GLU A 1 99  ? -5.165  15.917  23.140 1.00 10.68 ?  65   GLU A CA   1 
ATOM   767   C C    . GLU A 1 99  ? -5.003  17.214  22.366 1.00 10.88 ?  65   GLU A C    1 
ATOM   768   O O    . GLU A 1 99  ? -4.075  17.417  21.577 1.00 10.72 ?  65   GLU A O    1 
ATOM   769   C CB   . GLU A 1 99  ? -4.972  16.178  24.640 1.00 11.34 ?  65   GLU A CB   1 
ATOM   770   C CG   . GLU A 1 99  ? -5.914  15.401  25.540 1.00 11.90 ?  65   GLU A CG   1 
ATOM   771   C CD   . GLU A 1 99  ? -7.319  15.983  25.585 1.00 11.56 ?  65   GLU A CD   1 
ATOM   772   O OE1  . GLU A 1 99  ? -7.553  17.074  25.034 1.00 11.41 ?  65   GLU A OE1  1 
ATOM   773   O OE2  . GLU A 1 99  ? -8.189  15.295  26.177 1.00 11.29 ?  65   GLU A OE2  1 
ATOM   774   H H    . GLU A 1 99  ? -3.670  14.670  23.315 1.00 12.04 ?  65   GLU A H    1 
ATOM   775   H HA   . GLU A 1 99  ? -6.068  15.605  22.971 1.00 12.82 ?  65   GLU A HA   1 
ATOM   776   H HB2  . GLU A 1 99  ? -4.066  15.933  24.882 1.00 13.61 ?  65   GLU A HB2  1 
ATOM   777   H HB3  . GLU A 1 99  ? -5.117  17.122  24.810 1.00 13.61 ?  65   GLU A HB3  1 
ATOM   778   H HG2  . GLU A 1 99  ? -5.979  14.490  25.215 1.00 14.28 ?  65   GLU A HG2  1 
ATOM   779   H HG3  . GLU A 1 99  ? -5.560  15.407  26.443 1.00 14.28 ?  65   GLU A HG3  1 
ATOM   780   N N    . LYS A 1 100 ? -5.968  18.100  22.601 1.00 9.80  ?  66   LYS A N    1 
ATOM   781   C CA   . LYS A 1 100 ? -5.854  19.481  22.221 1.00 10.64 ?  66   LYS A CA   1 
ATOM   782   C C    . LYS A 1 100 ? -4.631  20.103  22.895 1.00 10.33 ?  66   LYS A C    1 
ATOM   783   O O    . LYS A 1 100 ? -4.014  19.536  23.788 1.00 11.17 ?  66   LYS A O    1 
ATOM   784   C CB   . LYS A 1 100 ? -7.147  20.207  22.631 1.00 11.45 ?  66   LYS A CB   1 
ATOM   785   C CG   . LYS A 1 100 ? -7.475  20.162  24.109 1.00 15.22 ?  66   LYS A CG   1 
ATOM   786   C CD   . LYS A 1 100 ? -8.836  20.735  24.462 1.00 10.96 ?  66   LYS A CD   1 
ATOM   787   C CE   . LYS A 1 100 ? -9.258  20.369  25.852 1.00 12.72 ?  66   LYS A CE   1 
ATOM   788   N NZ   . LYS A 1 100 ? -9.515  18.922  26.063 1.00 13.15 ?  66   LYS A NZ   1 
ATOM   789   H H    . LYS A 1 100 ? -6.712  17.912  22.988 1.00 11.76 ?  66   LYS A H    1 
ATOM   790   H HA   . LYS A 1 100 ? -5.737  19.575  21.263 1.00 12.77 ?  66   LYS A HA   1 
ATOM   791   H HB2  . LYS A 1 100 ? -7.065  21.141  22.381 1.00 13.74 ?  66   LYS A HB2  1 
ATOM   792   H HB3  . LYS A 1 100 ? -7.889  19.801  22.157 1.00 13.74 ?  66   LYS A HB3  1 
ATOM   793   H HG2  . LYS A 1 100 ? -7.460  19.238  24.403 1.00 18.26 ?  66   LYS A HG2  1 
ATOM   794   H HG3  . LYS A 1 100 ? -6.807  20.675  24.591 1.00 18.26 ?  66   LYS A HG3  1 
ATOM   795   H HD2  . LYS A 1 100 ? -8.801  21.702  24.401 1.00 13.15 ?  66   LYS A HD2  1 
ATOM   796   H HD3  . LYS A 1 100 ? -9.498  20.387  23.844 1.00 13.15 ?  66   LYS A HD3  1 
ATOM   797   H HE2  . LYS A 1 100 ? -8.556  20.632  26.467 1.00 15.26 ?  66   LYS A HE2  1 
ATOM   798   H HE3  . LYS A 1 100 ? -10.077 20.844  26.060 1.00 15.26 ?  66   LYS A HE3  1 
ATOM   799   H HZ1  . LYS A 1 100 ? -9.920  18.796  26.846 1.00 15.78 ?  66   LYS A HZ1  1 
ATOM   800   H HZ2  . LYS A 1 100 ? -10.038 18.608  25.414 1.00 15.78 ?  66   LYS A HZ2  1 
ATOM   801   H HZ3  . LYS A 1 100 ? -8.747  18.472  26.058 1.00 15.78 ?  66   LYS A HZ3  1 
ATOM   802   N N    . SER A 1 101 ? -4.272  21.300  22.412 1.00 11.50 ?  67   SER A N    1 
ATOM   803   C CA   . SER A 1 101 ? -3.051  21.987  22.828 1.00 11.32 ?  67   SER A CA   1 
ATOM   804   C C    . SER A 1 101 ? -1.858  21.057  22.706 1.00 11.13 ?  67   SER A C    1 
ATOM   805   O O    . SER A 1 101 ? -1.143  20.739  23.663 1.00 11.75 ?  67   SER A O    1 
ATOM   806   C CB   . SER A 1 101 ? -3.181  22.630  24.203 1.00 11.62 ?  67   SER A CB   1 
ATOM   807   O OG   . SER A 1 101 ? -4.086  23.714  24.112 1.00 12.82 ?  67   SER A OG   1 
ATOM   808   H H    . SER A 1 101 ? -4.731  21.739  21.831 1.00 13.80 ?  67   SER A H    1 
ATOM   809   H HA   . SER A 1 101 ? -2.896  22.728  22.222 1.00 13.58 ?  67   SER A HA   1 
ATOM   810   H HB2  . SER A 1 101 ? -3.519  21.977  24.835 1.00 13.94 ?  67   SER A HB2  1 
ATOM   811   H HB3  . SER A 1 101 ? -2.314  22.954  24.492 1.00 13.94 ?  67   SER A HB3  1 
ATOM   812   H HG   . SER A 1 101 ? -4.821  23.451  23.802 1.00 15.38 ?  67   SER A HG   1 
ATOM   813   N N    . GLN A 1 102 ? -1.605  20.644  21.471 1.00 10.40 ?  68   GLN A N    1 
ATOM   814   C CA   . GLN A 1 102 ? -0.578  19.649  21.187 1.00 12.18 ?  68   GLN A CA   1 
ATOM   815   C C    . GLN A 1 102 ? 0.684   20.337  20.675 1.00 12.00 ?  68   GLN A C    1 
ATOM   816   O O    . GLN A 1 102 ? 0.844   20.582  19.472 1.00 11.95 ?  68   GLN A O    1 
ATOM   817   C CB   . GLN A 1 102 ? -1.070  18.593  20.188 1.00 11.26 ?  68   GLN A CB   1 
ATOM   818   C CG   . GLN A 1 102 ? -0.229  17.309  20.183 1.00 12.48 ?  68   GLN A CG   1 
ATOM   819   C CD   . GLN A 1 102 ? -0.243  16.550  21.494 1.00 12.72 ?  68   GLN A CD   1 
ATOM   820   O OE1  . GLN A 1 102 ? 0.832   16.110  21.950 1.00 13.75 ?  68   GLN A OE1  1 
ATOM   821   N NE2  . GLN A 1 102 ? -1.392  16.361  22.129 1.00 11.19 ?  68   GLN A NE2  1 
ATOM   822   H H    . GLN A 1 102 ? -2.019  20.929  20.773 1.00 12.48 ?  68   GLN A H    1 
ATOM   823   H HA   . GLN A 1 102 ? -0.365  19.217  22.029 1.00 14.61 ?  68   GLN A HA   1 
ATOM   824   H HB2  . GLN A 1 102 ? -1.981  18.350  20.415 1.00 13.51 ?  68   GLN A HB2  1 
ATOM   825   H HB3  . GLN A 1 102 ? -1.040  18.970  19.295 1.00 13.51 ?  68   GLN A HB3  1 
ATOM   826   H HG2  . GLN A 1 102 ? -0.574  16.715  19.497 1.00 14.97 ?  68   GLN A HG2  1 
ATOM   827   H HG3  . GLN A 1 102 ? 0.692   17.541  19.988 1.00 14.97 ?  68   GLN A HG3  1 
ATOM   828   H HE21 . GLN A 1 102 ? -2.123  16.668  21.796 1.00 13.42 ?  68   GLN A HE21 1 
ATOM   829   H HE22 . GLN A 1 102 ? -1.406  15.931  22.874 1.00 13.42 ?  68   GLN A HE22 1 
ATOM   830   N N    . ALA A 1 103 ? 1.612   20.619  21.598 1.00 11.16 ?  69   ALA A N    1 
ATOM   831   C CA   . ALA A 1 103 ? 2.955   21.153  21.298 1.00 11.28 ?  69   ALA A CA   1 
ATOM   832   C C    . ALA A 1 103 ? 2.896   22.492  20.570 1.00 12.83 ?  69   ALA A C    1 
ATOM   833   O O    . ALA A 1 103 ? 3.784   22.835  19.779 1.00 13.02 ?  69   ALA A O    1 
ATOM   834   C CB   . ALA A 1 103 ? 3.819   20.116  20.570 1.00 12.52 ?  69   ALA A CB   1 
ATOM   835   H H    . ALA A 1 103 ? 1.486   20.505  22.442 1.00 13.39 ?  69   ALA A H    1 
ATOM   836   H HA   . ALA A 1 103 ? 3.407   21.340  22.136 1.00 13.54 ?  69   ALA A HA   1 
ATOM   837   H HB1  . ALA A 1 103 ? 4.615   20.552  20.228 1.00 15.03 ?  69   ALA A HB1  1 
ATOM   838   H HB2  . ALA A 1 103 ? 4.068   19.417  21.194 1.00 15.03 ?  69   ALA A HB2  1 
ATOM   839   H HB3  . ALA A 1 103 ? 3.308   19.738  19.837 1.00 15.03 ?  69   ALA A HB3  1 
ATOM   840   N N    . GLN A 1 104 ? 1.856   23.281  20.814 1.00 11.51 ?  70   GLN A N    1 
ATOM   841   C CA   . GLN A 1 104 ? 1.652   24.514  20.079 1.00 12.16 ?  70   GLN A CA   1 
ATOM   842   C C    . GLN A 1 104 ? 2.703   25.567  20.367 1.00 13.39 ?  70   GLN A C    1 
ATOM   843   O O    . GLN A 1 104 ? 2.831   26.501  19.566 1.00 14.67 ?  70   GLN A O    1 
ATOM   844   C CB   . GLN A 1 104 ? 0.252   25.054  20.381 1.00 13.33 ?  70   GLN A CB   1 
ATOM   845   C CG   . GLN A 1 104 ? 0.062   25.760  21.750 1.00 12.72 ?  70   GLN A CG   1 
ATOM   846   C CD   . GLN A 1 104 ? 0.029   24.850  22.919 1.00 12.87 ?  70   GLN A CD   1 
ATOM   847   O OE1  . GLN A 1 104 ? -0.159  23.626  22.791 1.00 14.22 ?  70   GLN A OE1  1 
ATOM   848   N NE2  . GLN A 1 104 ? 0.206   25.399  24.088 1.00 14.26 ?  70   GLN A NE2  1 
ATOM   849   H H    . GLN A 1 104 ? 1.251   23.121  21.404 1.00 13.82 ?  70   GLN A H    1 
ATOM   850   H HA   . GLN A 1 104 ? 1.710   24.324  19.129 1.00 14.60 ?  70   GLN A HA   1 
ATOM   851   H HB2  . GLN A 1 104 ? 0.024   25.700  19.694 1.00 15.99 ?  70   GLN A HB2  1 
ATOM   852   H HB3  . GLN A 1 104 ? -0.370  24.310  20.357 1.00 15.99 ?  70   GLN A HB3  1 
ATOM   853   H HG2  . GLN A 1 104 ? 0.798   26.378  21.882 1.00 15.26 ?  70   GLN A HG2  1 
ATOM   854   H HG3  . GLN A 1 104 ? -0.778  26.244  21.733 1.00 15.26 ?  70   GLN A HG3  1 
ATOM   855   H HE21 . GLN A 1 104 ? 0.334   26.248  24.150 1.00 17.11 ?  70   GLN A HE21 1 
ATOM   856   H HE22 . GLN A 1 104 ? 0.195   24.913  24.798 1.00 17.11 ?  70   GLN A HE22 1 
ATOM   857   N N    . ASN A 1 105 ? 3.421   25.492  21.484 1.00 11.61 ?  71   ASN A N    1 
ATOM   858   C CA   . ASN A 1 105 ? 4.418   26.521  21.753 1.00 12.91 ?  71   ASN A CA   1 
ATOM   859   C C    . ASN A 1 105 ? 5.723   26.200  21.052 1.00 15.47 ?  71   ASN A C    1 
ATOM   860   O O    . ASN A 1 105 ? 6.596   27.071  21.022 1.00 18.55 ?  71   ASN A O    1 
ATOM   861   C CB   . ASN A 1 105 ? 4.620   26.706  23.249 1.00 13.99 ?  71   ASN A CB   1 
ATOM   862   C CG   . ASN A 1 105 ? 3.436   27.376  23.913 1.00 14.81 ?  71   ASN A CG   1 
ATOM   863   O OD1  . ASN A 1 105 ? 2.562   27.934  23.230 1.00 18.49 ?  71   ASN A OD1  1 
ATOM   864   N ND2  . ASN A 1 105 ? 3.391   27.327  25.253 1.00 17.50 ?  71   ASN A ND2  1 
ATOM   865   H H    . ASN A 1 105 ? 3.352   24.877  22.080 1.00 13.93 ?  71   ASN A H    1 
ATOM   866   H HA   . ASN A 1 105 ? 4.105   27.382  21.433 1.00 15.50 ?  71   ASN A HA   1 
ATOM   867   H HB2  . ASN A 1 105 ? 4.745   25.837  23.662 1.00 16.79 ?  71   ASN A HB2  1 
ATOM   868   H HB3  . ASN A 1 105 ? 5.402   27.259  23.398 1.00 16.79 ?  71   ASN A HB3  1 
ATOM   869   H HD21 . ASN A 1 105 ? 2.737   27.694  25.675 1.00 21.00 ?  71   ASN A HD21 1 
ATOM   870   H HD22 . ASN A 1 105 ? 4.015   26.928  25.690 1.00 21.00 ?  71   ASN A HD22 1 
ATOM   871   N N    . THR A 1 106 ? 5.855   25.022  20.450 1.00 13.69 ?  72   THR A N    1 
ATOM   872   C CA   . THR A 1 106 ? 6.968   24.693  19.554 1.00 13.10 ?  72   THR A CA   1 
ATOM   873   C C    . THR A 1 106 ? 6.590   24.849  18.096 1.00 13.55 ?  72   THR A C    1 
ATOM   874   O O    . THR A 1 106 ? 7.311   25.490  17.320 1.00 15.04 ?  72   THR A O    1 
ATOM   875   C CB   . THR A 1 106 ? 7.476   23.275  19.799 1.00 13.46 ?  72   THR A CB   1 
ATOM   876   O OG1  . THR A 1 106 ? 7.866   23.124  21.162 1.00 12.84 ?  72   THR A OG1  1 
ATOM   877   C CG2  . THR A 1 106 ? 8.662   22.961  18.853 1.00 14.80 ?  72   THR A CG2  1 
ATOM   878   H H    . THR A 1 106 ? 5.297   24.375  20.545 1.00 16.43 ?  72   THR A H    1 
ATOM   879   H HA   . THR A 1 106 ? 7.700   25.298  19.754 1.00 15.72 ?  72   THR A HA   1 
ATOM   880   H HB   . THR A 1 106 ? 6.771   22.636  19.614 1.00 16.15 ?  72   THR A HB   1 
ATOM   881   H HG1  . THR A 1 106 ? 8.354   23.766  21.394 1.00 15.41 ?  72   THR A HG1  1 
ATOM   882   H HG21 . THR A 1 106 ? 9.059   22.109  19.091 1.00 17.76 ?  72   THR A HG21 1 
ATOM   883   H HG22 . THR A 1 106 ? 8.351   22.919  17.935 1.00 17.76 ?  72   THR A HG22 1 
ATOM   884   H HG23 . THR A 1 106 ? 9.337   23.654  18.926 1.00 17.76 ?  72   THR A HG23 1 
ATOM   885   N N    . TYR A 1 107 ? 5.424   24.324  17.706 1.00 13.71 ?  73   TYR A N    1 
ATOM   886   C CA   . TYR A 1 107 ? 5.001   24.228  16.317 1.00 13.58 ?  73   TYR A CA   1 
ATOM   887   C C    . TYR A 1 107 ? 4.002   25.288  15.911 1.00 13.56 ?  73   TYR A C    1 
ATOM   888   O O    . TYR A 1 107 ? 3.637   25.325  14.732 1.00 17.18 ?  73   TYR A O    1 
ATOM   889   C CB   . TYR A 1 107 ? 4.468   22.806  16.019 1.00 13.54 ?  73   TYR A CB   1 
ATOM   890   C CG   . TYR A 1 107 ? 5.545   21.777  16.241 1.00 12.78 ?  73   TYR A CG   1 
ATOM   891   C CD1  . TYR A 1 107 ? 6.540   21.575  15.276 1.00 13.91 ?  73   TYR A CD1  1 
ATOM   892   C CD2  . TYR A 1 107 ? 5.605   20.996  17.381 1.00 14.14 ?  73   TYR A CD2  1 
ATOM   893   C CE1  . TYR A 1 107 ? 7.550   20.636  15.481 1.00 14.21 ?  73   TYR A CE1  1 
ATOM   894   C CE2  . TYR A 1 107 ? 6.625   20.082  17.569 1.00 15.92 ?  73   TYR A CE2  1 
ATOM   895   C CZ   . TYR A 1 107 ? 7.584   19.915  16.609 1.00 14.25 ?  73   TYR A CZ   1 
ATOM   896   O OH   . TYR A 1 107 ? 8.620   19.002  16.812 1.00 19.28 ?  73   TYR A OH   1 
ATOM   897   H H    . TYR A 1 107 ? 4.843   24.006  18.254 1.00 16.46 ?  73   TYR A H    1 
ATOM   898   H HA   . TYR A 1 107 ? 5.775   24.362  15.749 1.00 16.29 ?  73   TYR A HA   1 
ATOM   899   H HB2  . TYR A 1 107 ? 3.726   22.608  16.611 1.00 16.25 ?  73   TYR A HB2  1 
ATOM   900   H HB3  . TYR A 1 107 ? 4.179   22.756  15.095 1.00 16.25 ?  73   TYR A HB3  1 
ATOM   901   H HD1  . TYR A 1 107 ? 6.527   22.073  14.491 1.00 16.69 ?  73   TYR A HD1  1 
ATOM   902   H HD2  . TYR A 1 107 ? 4.948   21.087  18.032 1.00 16.97 ?  73   TYR A HD2  1 
ATOM   903   H HE1  . TYR A 1 107 ? 8.203   20.510  14.831 1.00 17.05 ?  73   TYR A HE1  1 
ATOM   904   H HE2  . TYR A 1 107 ? 6.658   19.579  18.351 1.00 19.11 ?  73   TYR A HE2  1 
ATOM   905   H HH   . TYR A 1 107 ? 8.583   18.694  17.593 1.00 23.14 ?  73   TYR A HH   1 
ATOM   906   N N    . GLY A 1 108 ? 3.598   26.162  16.809 1.00 13.59 ?  74   GLY A N    1 
ATOM   907   C CA   . GLY A 1 108 ? 2.735   27.289  16.515 1.00 12.59 ?  74   GLY A CA   1 
ATOM   908   C C    . GLY A 1 108 ? 1.253   27.001  16.614 1.00 14.78 ?  74   GLY A C    1 
ATOM   909   O O    . GLY A 1 108 ? 0.465   27.942  16.749 1.00 19.08 ?  74   GLY A O    1 
ATOM   910   H H    . GLY A 1 108 ? 3.822   26.124  17.638 1.00 16.31 ?  74   GLY A H    1 
ATOM   911   H HA2  . GLY A 1 108 ? 2.939   28.006  17.136 1.00 15.11 ?  74   GLY A HA2  1 
ATOM   912   H HA3  . GLY A 1 108 ? 2.918   27.592  15.612 1.00 15.11 ?  74   GLY A HA3  1 
ATOM   913   N N    . SER A 1 109 ? 0.853   25.744  16.518 1.00 11.82 ?  75   SER A N    1 
ATOM   914   C CA   . SER A 1 109 ? -0.546  25.355  16.476 1.00 11.28 ?  75   SER A CA   1 
ATOM   915   C C    . SER A 1 109 ? -0.631  23.888  16.871 1.00 12.25 ?  75   SER A C    1 
ATOM   916   O O    . SER A 1 109 ? 0.305   23.105  16.679 1.00 10.88 ?  75   SER A O    1 
ATOM   917   C CB   . SER A 1 109 ? -1.183  25.504  15.104 1.00 12.27 ?  75   SER A CB   1 
ATOM   918   O OG   . SER A 1 109 ? -0.540  24.695  14.143 1.00 13.44 ?  75   SER A OG   1 
ATOM   919   H H    . SER A 1 109 ? 1.390   25.074  16.473 1.00 14.18 ?  75   SER A H    1 
ATOM   920   H HA   . SER A 1 109 ? -1.025  25.923  17.099 1.00 13.54 ?  75   SER A HA   1 
ATOM   921   H HB2  . SER A 1 109 ? -2.115  25.241  15.162 1.00 14.72 ?  75   SER A HB2  1 
ATOM   922   H HB3  . SER A 1 109 ? -1.116  26.431  14.828 1.00 14.72 ?  75   SER A HB3  1 
ATOM   923   H HG   . SER A 1 109 ? 0.134   25.093  13.838 1.00 16.13 ?  75   SER A HG   1 
ATOM   924   N N    . THR A 1 110 ? -1.820  23.507  17.346 1.00 10.91 ?  76   THR A N    1 
ATOM   925   C CA   . THR A 1 110 ? -2.094  22.100  17.581 1.00 10.65 ?  76   THR A CA   1 
ATOM   926   C C    . THR A 1 110 ? -2.051  21.287  16.298 1.00 11.08 ?  76   THR A C    1 
ATOM   927   O O    . THR A 1 110 ? -1.615  20.124  16.315 1.00 11.76 ?  76   THR A O    1 
ATOM   928   C CB   . THR A 1 110 ? -3.440  21.956  18.288 1.00 11.04 ?  76   THR A CB   1 
ATOM   929   O OG1  . THR A 1 110 ? -3.247  22.459  19.613 1.00 11.75 ?  76   THR A OG1  1 
ATOM   930   C CG2  . THR A 1 110 ? -3.938  20.539  18.327 1.00 11.78 ?  76   THR A CG2  1 
ATOM   931   H H    . THR A 1 110 ? -2.470  24.037  17.536 1.00 13.09 ?  76   THR A H    1 
ATOM   932   H HA   . THR A 1 110 ? -1.406  21.737  18.161 1.00 12.78 ?  76   THR A HA   1 
ATOM   933   H HB   . THR A 1 110 ? -4.130  22.444  17.812 1.00 13.25 ?  76   THR A HB   1 
ATOM   934   H HG1  . THR A 1 110 ? -3.989  22.557  19.995 1.00 14.10 ?  76   THR A HG1  1 
ATOM   935   H HG21 . THR A 1 110 ? -4.679  20.465  18.949 1.00 14.14 ?  76   THR A HG21 1 
ATOM   936   H HG22 . THR A 1 110 ? -4.239  20.268  17.446 1.00 14.14 ?  76   THR A HG22 1 
ATOM   937   H HG23 . THR A 1 110 ? -3.227  19.945  18.614 1.00 14.14 ?  76   THR A HG23 1 
ATOM   938   N N    . GLU A 1 111 ? -2.528  21.842  15.194 1.00 11.89 ?  77   GLU A N    1 
ATOM   939   C CA   . GLU A 1 111 ? -2.525  21.053  13.967 1.00 11.76 ?  77   GLU A CA   1 
ATOM   940   C C    . GLU A 1 111 ? -1.096  20.653  13.602 1.00 11.51 ?  77   GLU A C    1 
ATOM   941   O O    . GLU A 1 111 ? -0.826  19.488  13.304 1.00 12.42 ?  77   GLU A O    1 
ATOM   942   C CB   . GLU A 1 111 ? -3.189  21.820  12.831 1.00 13.72 ?  77   GLU A CB   1 
ATOM   943   C CG   . GLU A 1 111 ? -4.678  22.132  13.069 1.00 12.03 ?  77   GLU A CG   1 
ATOM   944   C CD   . GLU A 1 111 ? -4.952  23.489  13.712 1.00 11.87 ?  77   GLU A CD   1 
ATOM   945   O OE1  . GLU A 1 111 ? -4.112  23.961  14.485 1.00 12.39 ?  77   GLU A OE1  1 
ATOM   946   O OE2  . GLU A 1 111 ? -6.052  24.065  13.453 1.00 12.13 ?  77   GLU A OE2  1 
ATOM   947   H H    . GLU A 1 111 ? -2.846  22.639  15.129 1.00 14.27 ?  77   GLU A H    1 
ATOM   948   H HA   . GLU A 1 111 ? -3.046  20.247  14.107 1.00 14.11 ?  77   GLU A HA   1 
ATOM   949   H HB2  . GLU A 1 111 ? -2.726  22.665  12.714 1.00 16.46 ?  77   GLU A HB2  1 
ATOM   950   H HB3  . GLU A 1 111 ? -3.125  21.292  12.020 1.00 16.46 ?  77   GLU A HB3  1 
ATOM   951   H HG2  . GLU A 1 111 ? -5.137  22.116  12.214 1.00 14.44 ?  77   GLU A HG2  1 
ATOM   952   H HG3  . GLU A 1 111 ? -5.045  21.452  13.655 1.00 14.44 ?  77   GLU A HG3  1 
ATOM   953   N N    . GLU A 1 112 ? -0.162  21.598  13.619 1.00 11.88 ?  78   GLU A N    1 
ATOM   954   C CA   . GLU A 1 112 ? 1.231   21.284  13.294 1.00 11.64 ?  78   GLU A CA   1 
ATOM   955   C C    . GLU A 1 112 ? 1.915   20.468  14.365 1.00 13.21 ?  78   GLU A C    1 
ATOM   956   O O    . GLU A 1 112 ? 2.713   19.588  14.046 1.00 12.88 ?  78   GLU A O    1 
ATOM   957   C CB   . GLU A 1 112 ? 2.020   22.548  12.965 1.00 13.86 ?  78   GLU A CB   1 
ATOM   958   C CG   . GLU A 1 112 ? 1.495   23.226  11.690 1.00 17.10 ?  78   GLU A CG   1 
ATOM   959   C CD   . GLU A 1 112 ? 1.623   22.397  10.407 1.00 20.00 ?  78   GLU A CD   1 
ATOM   960   O OE1  . GLU A 1 112 ? 2.403   21.443  10.351 1.00 20.79 ?  78   GLU A OE1  1 
ATOM   961   O OE2  . GLU A 1 112 ? 0.920   22.747  9.433  1.00 26.40 ?  78   GLU A OE2  1 
ATOM   962   H H    . GLU A 1 112 ? -0.304  22.424  13.813 1.00 14.25 ?  78   GLU A H    1 
ATOM   963   H HA   . GLU A 1 112 ? 1.220   20.737  12.493 1.00 13.97 ?  78   GLU A HA   1 
ATOM   964   H HB2  . GLU A 1 112 ? 1.941   23.176  13.700 1.00 16.63 ?  78   GLU A HB2  1 
ATOM   965   H HB3  . GLU A 1 112 ? 2.952   22.316  12.826 1.00 16.63 ?  78   GLU A HB3  1 
ATOM   966   H HG2  . GLU A 1 112 ? 0.554   23.423  11.813 1.00 20.53 ?  78   GLU A HG2  1 
ATOM   967   H HG3  . GLU A 1 112 ? 1.992   24.048  11.553 1.00 20.53 ?  78   GLU A HG3  1 
ATOM   968   N N    . GLY A 1 113 ? 1.607   20.720  15.638 1.00 11.93 ?  79   GLY A N    1 
ATOM   969   C CA   . GLY A 1 113 ? 2.214   19.932  16.700 1.00 11.84 ?  79   GLY A CA   1 
ATOM   970   C C    . GLY A 1 113 ? 1.752   18.501  16.694 1.00 10.90 ?  79   GLY A C    1 
ATOM   971   O O    . GLY A 1 113 ? 2.521   17.599  17.026 1.00 11.96 ?  79   GLY A O    1 
ATOM   972   H H    . GLY A 1 113 ? 1.060   21.328  15.905 1.00 14.32 ?  79   GLY A H    1 
ATOM   973   H HA2  . GLY A 1 113 ? 3.178   19.942  16.594 1.00 14.20 ?  79   GLY A HA2  1 
ATOM   974   H HA3  . GLY A 1 113 ? 1.987   20.323  17.558 1.00 14.20 ?  79   GLY A HA3  1 
ATOM   975   N N    . THR A 1 114 ? 0.520   18.274  16.274 1.00 10.26 ?  80   THR A N    1 
ATOM   976   C CA   . THR A 1 114 ? 0.006   16.927  16.131 1.00 10.78 ?  80   THR A CA   1 
ATOM   977   C C    . THR A 1 114 ? 0.746   16.203  15.011 1.00 12.40 ?  80   THR A C    1 
ATOM   978   O O    . THR A 1 114 ? 1.175   15.044  15.177 1.00 11.84 ?  80   THR A O    1 
ATOM   979   C CB   . THR A 1 114 ? -1.493  16.988  15.829 1.00 11.17 ?  80   THR A CB   1 
ATOM   980   O OG1  . THR A 1 114 ? -2.157  17.548  16.969 1.00 12.05 ?  80   THR A OG1  1 
ATOM   981   C CG2  . THR A 1 114 ? -2.062  15.638  15.566 1.00 12.44 ?  80   THR A CG2  1 
ATOM   982   H H    . THR A 1 114 ? -0.044  18.888  16.063 1.00 12.31 ?  80   THR A H    1 
ATOM   983   H HA   . THR A 1 114 ? 0.132   16.435  16.957 1.00 12.93 ?  80   THR A HA   1 
ATOM   984   H HB   . THR A 1 114 ? -1.637  17.526  15.035 1.00 13.40 ?  80   THR A HB   1 
ATOM   985   H HG1  . THR A 1 114 ? -2.209  18.382  16.891 1.00 14.46 ?  80   THR A HG1  1 
ATOM   986   H HG21 . THR A 1 114 ? -3.007  15.710  15.360 1.00 14.92 ?  80   THR A HG21 1 
ATOM   987   H HG22 . THR A 1 114 ? -1.607  15.226  14.816 1.00 14.92 ?  80   THR A HG22 1 
ATOM   988   H HG23 . THR A 1 114 ? -1.954  15.074  16.348 1.00 14.92 ?  80   THR A HG23 1 
ATOM   989   N N    . LEU A 1 115 ? 0.872   16.844  13.843 1.00 11.50 ?  81   LEU A N    1 
ATOM   990   C CA   . LEU A 1 115 ? 1.561   16.196  12.728 1.00 12.55 ?  81   LEU A CA   1 
ATOM   991   C C    . LEU A 1 115 ? 2.991   15.836  13.110 1.00 11.76 ?  81   LEU A C    1 
ATOM   992   O O    . LEU A 1 115 ? 3.473   14.731  12.800 1.00 12.71 ?  81   LEU A O    1 
ATOM   993   C CB   . LEU A 1 115 ? 1.564   17.111  11.505 1.00 12.74 ?  81   LEU A CB   1 
ATOM   994   C CG   . LEU A 1 115 ? 0.206   17.344  10.844 1.00 14.15 ?  81   LEU A CG   1 
ATOM   995   C CD1  . LEU A 1 115 ? 0.346   18.431  9.773  1.00 15.68 ?  81   LEU A CD1  1 
ATOM   996   C CD2  . LEU A 1 115 ? -0.357  16.087  10.255 1.00 13.77 ?  81   LEU A CD2  1 
ATOM   997   H H    . LEU A 1 115 ? 0.575   17.634  13.676 1.00 13.80 ?  81   LEU A H    1 
ATOM   998   H HA   . LEU A 1 115 ? 1.084   15.383  12.499 1.00 15.06 ?  81   LEU A HA   1 
ATOM   999   H HB2  . LEU A 1 115 ? 1.905   17.978  11.776 1.00 15.29 ?  81   LEU A HB2  1 
ATOM   1000  H HB3  . LEU A 1 115 ? 2.147   16.720  10.836 1.00 15.29 ?  81   LEU A HB3  1 
ATOM   1001  H HG   . LEU A 1 115 ? -0.426  17.637  11.520 1.00 16.98 ?  81   LEU A HG   1 
ATOM   1002  H HD11 . LEU A 1 115 ? -0.532  18.636  9.415  1.00 18.82 ?  81   LEU A HD11 1 
ATOM   1003  H HD12 . LEU A 1 115 ? 0.732   19.224  10.177 1.00 18.82 ?  81   LEU A HD12 1 
ATOM   1004  H HD13 . LEU A 1 115 ? 0.924   18.105  9.066  1.00 18.82 ?  81   LEU A HD13 1 
ATOM   1005  H HD21 . LEU A 1 115 ? -1.166  16.303  9.765  1.00 16.53 ?  81   LEU A HD21 1 
ATOM   1006  H HD22 . LEU A 1 115 ? 0.298   15.697  9.656  1.00 16.53 ?  81   LEU A HD22 1 
ATOM   1007  H HD23 . LEU A 1 115 ? -0.561  15.466  10.972 1.00 16.53 ?  81   LEU A HD23 1 
ATOM   1008  N N    . ALA A 1 116 ? 3.685   16.732  13.796 1.00 11.88 ?  82   ALA A N    1 
ATOM   1009  C CA   . ALA A 1 116 ? 5.079   16.458  14.147 1.00 12.44 ?  82   ALA A CA   1 
ATOM   1010  C C    . ALA A 1 116 ? 5.159   15.345  15.175 1.00 12.84 ?  82   ALA A C    1 
ATOM   1011  O O    . ALA A 1 116 ? 6.057   14.490  15.130 1.00 14.33 ?  82   ALA A O    1 
ATOM   1012  C CB   . ALA A 1 116 ? 5.756   17.737  14.629 1.00 14.25 ?  82   ALA A CB   1 
ATOM   1013  H H    . ALA A 1 116 ? 3.385   17.491  14.068 1.00 14.26 ?  82   ALA A H    1 
ATOM   1014  H HA   . ALA A 1 116 ? 5.566   16.163  13.361 1.00 14.92 ?  82   ALA A HA   1 
ATOM   1015  H HB1  . ALA A 1 116 ? 6.677   17.539  14.861 1.00 17.10 ?  82   ALA A HB1  1 
ATOM   1016  H HB2  . ALA A 1 116 ? 5.729   18.396  13.917 1.00 17.10 ?  82   ALA A HB2  1 
ATOM   1017  H HB3  . ALA A 1 116 ? 5.283   18.071  15.407 1.00 17.10 ?  82   ALA A HB3  1 
ATOM   1018  N N    . THR A 1 117 ? 4.273   15.357  16.182 1.00 11.88 ?  83   THR A N    1 
ATOM   1019  C CA   . THR A 1 117 ? 4.335   14.329  17.191 1.00 10.81 ?  83   THR A CA   1 
ATOM   1020  C C    . THR A 1 117 ? 4.020   12.976  16.588 1.00 11.94 ?  83   THR A C    1 
ATOM   1021  O O    . THR A 1 117 ? 4.709   11.975  16.865 1.00 13.00 ?  83   THR A O    1 
ATOM   1022  C CB   . THR A 1 117 ? 3.354   14.688  18.318 1.00 12.04 ?  83   THR A CB   1 
ATOM   1023  O OG1  . THR A 1 117 ? 3.730   15.932  18.919 1.00 12.40 ?  83   THR A OG1  1 
ATOM   1024  C CG2  . THR A 1 117 ? 3.311   13.634  19.374 1.00 12.51 ?  83   THR A CG2  1 
ATOM   1025  H H    . THR A 1 117 ? 3.649   15.939  16.289 1.00 14.26 ?  83   THR A H    1 
ATOM   1026  H HA   . THR A 1 117 ? 5.227   14.278  17.570 1.00 12.97 ?  83   THR A HA   1 
ATOM   1027  H HB   . THR A 1 117 ? 2.467   14.762  17.933 1.00 14.45 ?  83   THR A HB   1 
ATOM   1028  H HG1  . THR A 1 117 ? 3.717   16.544  18.344 1.00 14.87 ?  83   THR A HG1  1 
ATOM   1029  H HG21 . THR A 1 117 ? 2.807   13.951  20.139 1.00 15.01 ?  83   THR A HG21 1 
ATOM   1030  H HG22 . THR A 1 117 ? 2.887   12.833  19.027 1.00 15.01 ?  83   THR A HG22 1 
ATOM   1031  H HG23 . THR A 1 117 ? 4.212   13.414  19.660 1.00 15.01 ?  83   THR A HG23 1 
ATOM   1032  N N    . ALA A 1 118 ? 2.939   12.891  15.799 1.00 11.98 ?  84   ALA A N    1 
ATOM   1033  C CA   . ALA A 1 118 ? 2.567   11.616  15.204 1.00 12.05 ?  84   ALA A CA   1 
ATOM   1034  C C    . ALA A 1 118 ? 3.666   11.085  14.296 1.00 12.69 ?  84   ALA A C    1 
ATOM   1035  O O    . ALA A 1 118 ? 3.929   9.875   14.290 1.00 12.99 ?  84   ALA A O    1 
ATOM   1036  C CB   . ALA A 1 118 ? 1.248   11.756  14.438 1.00 13.06 ?  84   ALA A CB   1 
ATOM   1037  H H    . ALA A 1 118 ? 2.419   13.547  15.601 1.00 14.37 ?  84   ALA A H    1 
ATOM   1038  H HA   . ALA A 1 118 ? 2.431   10.970  15.914 1.00 14.46 ?  84   ALA A HA   1 
ATOM   1039  H HB1  . ALA A 1 118 ? 1.033   10.906  14.023 1.00 15.67 ?  84   ALA A HB1  1 
ATOM   1040  H HB2  . ALA A 1 118 ? 0.547   12.008  15.059 1.00 15.67 ?  84   ALA A HB2  1 
ATOM   1041  H HB3  . ALA A 1 118 ? 1.349   12.440  13.758 1.00 15.67 ?  84   ALA A HB3  1 
ATOM   1042  N N    . SER A 1 119 ? 4.296   11.959  13.494 1.00 12.60 ?  85   SER A N    1 
ATOM   1043  C CA   . SER A 1 119 ? 5.391   11.466  12.645 1.00 13.47 ?  85   SER A CA   1 
ATOM   1044  C C    . SER A 1 119 ? 6.496   10.862  13.496 1.00 13.52 ?  85   SER A C    1 
ATOM   1045  O O    . SER A 1 119 ? 7.025   9.794   13.181 1.00 14.97 ?  85   SER A O    1 
ATOM   1046  C CB   . SER A 1 119 ? 5.913   12.598  11.803 1.00 15.76 ?  85   SER A CB   1 
ATOM   1047  O OG   . SER A 1 119 ? 7.139   12.196  11.194 1.00 22.25 ?  85   SER A OG   1 
ATOM   1048  H H    . SER A 1 119 ? 4.118   12.797  13.426 1.00 15.12 ?  85   SER A H    1 
ATOM   1049  H HA   . SER A 1 119 ? 5.064   10.774  12.049 1.00 16.16 ?  85   SER A HA   1 
ATOM   1050  H HB2  . SER A 1 119 ? 5.265   12.814  11.115 1.00 18.91 ?  85   SER A HB2  1 
ATOM   1051  H HB3  . SER A 1 119 ? 6.070   13.373  12.365 1.00 18.91 ?  85   SER A HB3  1 
ATOM   1052  H HG   . SER A 1 119 ? 7.493   12.850  10.803 1.00 26.70 ?  85   SER A HG   1 
ATOM   1053  N N    . ALA A 1 120 ? 6.858   11.509  14.583 1.00 13.32 ?  86   ALA A N    1 
ATOM   1054  C CA   . ALA A 1 120 ? 7.936   10.998  15.418 1.00 13.12 ?  86   ALA A CA   1 
ATOM   1055  C C    . ALA A 1 120 ? 7.564   9.684   16.090 1.00 14.39 ?  86   ALA A C    1 
ATOM   1056  O O    . ALA A 1 120 ? 8.380   8.749   16.141 1.00 15.12 ?  86   ALA A O    1 
ATOM   1057  C CB   . ALA A 1 120 ? 8.302   12.044  16.446 1.00 15.38 ?  86   ALA A CB   1 
ATOM   1058  H H    . ALA A 1 120 ? 6.503   12.241  14.862 1.00 15.98 ?  86   ALA A H    1 
ATOM   1059  H HA   . ALA A 1 120 ? 8.711   10.821  14.862 1.00 15.74 ?  86   ALA A HA   1 
ATOM   1060  H HB1  . ALA A 1 120 ? 9.030   11.709  16.992 1.00 18.46 ?  86   ALA A HB1  1 
ATOM   1061  H HB2  . ALA A 1 120 ? 8.576   12.854  15.988 1.00 18.46 ?  86   ALA A HB2  1 
ATOM   1062  H HB3  . ALA A 1 120 ? 7.528   12.224  17.002 1.00 18.46 ?  86   ALA A HB3  1 
ATOM   1063  N N    . ILE A 1 121 ? 6.331   9.556   16.584 1.00 13.17 ?  87   ILE A N    1 
ATOM   1064  C CA   . ILE A 1 121 ? 5.888   8.280   17.152 1.00 14.75 ?  87   ILE A CA   1 
ATOM   1065  C C    . ILE A 1 121 ? 6.007   7.177   16.110 1.00 13.60 ?  87   ILE A C    1 
ATOM   1066  O O    . ILE A 1 121 ? 6.542   6.096   16.384 1.00 13.57 ?  87   ILE A O    1 
ATOM   1067  C CB   . ILE A 1 121 ? 4.429   8.399   17.659 1.00 13.89 ?  87   ILE A CB   1 
ATOM   1068  C CG1  . ILE A 1 121 ? 4.376   9.352   18.848 1.00 13.62 ?  87   ILE A CG1  1 
ATOM   1069  C CG2  . ILE A 1 121 ? 3.905   7.024   18.014 1.00 14.40 ?  87   ILE A CG2  1 
ATOM   1070  C CD1  . ILE A 1 121 ? 2.959   9.694   19.234 1.00 13.69 ?  87   ILE A CD1  1 
ATOM   1071  H H    . ILE A 1 121 ? 5.741   10.181  16.604 1.00 15.80 ?  87   ILE A H    1 
ATOM   1072  H HA   . ILE A 1 121 ? 6.460   8.059   17.904 1.00 17.70 ?  87   ILE A HA   1 
ATOM   1073  H HB   . ILE A 1 121 ? 3.864   8.765   16.961 1.00 16.66 ?  87   ILE A HB   1 
ATOM   1074  H HG12 . ILE A 1 121 ? 4.806   8.935   19.611 1.00 16.35 ?  87   ILE A HG12 1 
ATOM   1075  H HG13 . ILE A 1 121 ? 4.835   10.175  18.617 1.00 16.35 ?  87   ILE A HG13 1 
ATOM   1076  H HG21 . ILE A 1 121 ? 3.045   7.118   18.455 1.00 17.28 ?  87   ILE A HG21 1 
ATOM   1077  H HG22 . ILE A 1 121 ? 3.804   6.505   17.201 1.00 17.28 ?  87   ILE A HG22 1 
ATOM   1078  H HG23 . ILE A 1 121 ? 4.536   6.589   18.609 1.00 17.28 ?  87   ILE A HG23 1 
ATOM   1079  H HD11 . ILE A 1 121 ? 2.977   10.348  19.951 1.00 16.43 ?  87   ILE A HD11 1 
ATOM   1080  H HD12 . ILE A 1 121 ? 2.501   10.062  18.462 1.00 16.43 ?  87   ILE A HD12 1 
ATOM   1081  H HD13 . ILE A 1 121 ? 2.510   8.888   19.533 1.00 16.43 ?  87   ILE A HD13 1 
ATOM   1082  N N    . LYS A 1 122 ? 5.492   7.426   14.892 1.00 13.36 ?  88   LYS A N    1 
ATOM   1083  C CA   . LYS A 1 122 ? 5.441   6.366   13.882 1.00 14.78 ?  88   LYS A CA   1 
ATOM   1084  C C    . LYS A 1 122 ? 6.816   5.958   13.405 1.00 16.32 ?  88   LYS A C    1 
ATOM   1085  O O    . LYS A 1 122 ? 7.019   4.793   13.055 1.00 16.87 ?  88   LYS A O    1 
ATOM   1086  C CB   . LYS A 1 122 ? 4.556   6.796   12.718 1.00 16.51 ?  88   LYS A CB   1 
ATOM   1087  C CG   . LYS A 1 122 ? 3.084   6.885   13.034 1.00 16.19 ?  88   LYS A CG   1 
ATOM   1088  C CD   . LYS A 1 122 ? 2.449   5.597   13.327 1.00 18.44 ?  88   LYS A CD   1 
ATOM   1089  C CE   . LYS A 1 122 ? 0.914   5.701   13.370 1.00 18.21 ?  88   LYS A CE   1 
ATOM   1090  N NZ   . LYS A 1 122 ? 0.306   4.370   13.210 1.00 20.01 ?  88   LYS A NZ   1 
ATOM   1091  H H    . LYS A 1 122 ? 5.174   8.183   14.636 1.00 16.03 ?  88   LYS A H    1 
ATOM   1092  H HA   . LYS A 1 122 ? 5.038   5.578   14.280 1.00 17.74 ?  88   LYS A HA   1 
ATOM   1093  H HB2  . LYS A 1 122 ? 4.843   7.674   12.422 1.00 19.81 ?  88   LYS A HB2  1 
ATOM   1094  H HB3  . LYS A 1 122 ? 4.660   6.153   11.999 1.00 19.81 ?  88   LYS A HB3  1 
ATOM   1095  H HG2  . LYS A 1 122 ? 2.968   7.452   13.813 1.00 19.43 ?  88   LYS A HG2  1 
ATOM   1096  H HG3  . LYS A 1 122 ? 2.626   7.271   12.272 1.00 19.43 ?  88   LYS A HG3  1 
ATOM   1097  H HD2  . LYS A 1 122 ? 2.689   4.960   12.636 1.00 22.12 ?  88   LYS A HD2  1 
ATOM   1098  H HD3  . LYS A 1 122 ? 2.755   5.280   14.191 1.00 22.12 ?  88   LYS A HD3  1 
ATOM   1099  H HE2  . LYS A 1 122 ? 0.637   6.067   14.225 1.00 21.85 ?  88   LYS A HE2  1 
ATOM   1100  H HE3  . LYS A 1 122 ? 0.605   6.271   12.649 1.00 21.85 ?  88   LYS A HE3  1 
ATOM   1101  H HZ1  . LYS A 1 122 ? 0.593   3.993   12.457 1.00 24.01 ?  88   LYS A HZ1  1 
ATOM   1102  H HZ2  . LYS A 1 122 ? 0.528   3.849   13.897 1.00 24.01 ?  88   LYS A HZ2  1 
ATOM   1103  H HZ3  . LYS A 1 122 ? -0.580  4.442   13.177 1.00 24.01 ?  88   LYS A HZ3  1 
ATOM   1104  N N    . LEU A 1 123 ? 7.779   6.856   13.413 1.00 14.69 ?  89   LEU A N    1 
ATOM   1105  C CA   . LEU A 1 123 ? 9.136   6.475   13.025 1.00 16.72 ?  89   LEU A CA   1 
ATOM   1106  C C    . LEU A 1 123 ? 9.757   5.569   14.058 1.00 19.05 ?  89   LEU A C    1 
ATOM   1107  O O    . LEU A 1 123 ? 10.613  4.742   13.719 1.00 23.03 ?  89   LEU A O    1 
ATOM   1108  C CB   . LEU A 1 123 ? 9.987   7.719   12.820 1.00 17.75 ?  89   LEU A CB   1 
ATOM   1109  C CG   . LEU A 1 123 ? 9.689   8.420   11.504 1.00 21.98 ?  89   LEU A CG   1 
ATOM   1110  C CD1  . LEU A 1 123 ? 10.392  9.758   11.451 1.00 23.32 ?  89   LEU A CD1  1 
ATOM   1111  C CD2  . LEU A 1 123 ? 10.128  7.562   10.304 1.00 30.43 ?  89   LEU A CD2  1 
ATOM   1112  H H    . LEU A 1 123 ? 7.684   7.682   13.635 1.00 17.63 ?  89   LEU A H    1 
ATOM   1113  H HA   . LEU A 1 123 ? 9.108   5.998   12.181 1.00 20.07 ?  89   LEU A HA   1 
ATOM   1114  H HB2  . LEU A 1 123 ? 9.812   8.343   13.541 1.00 21.30 ?  89   LEU A HB2  1 
ATOM   1115  H HB3  . LEU A 1 123 ? 10.923  7.465   12.821 1.00 21.30 ?  89   LEU A HB3  1 
ATOM   1116  H HG   . LEU A 1 123 ? 8.731   8.561   11.445 1.00 26.38 ?  89   LEU A HG   1 
ATOM   1117  H HD11 . LEU A 1 123 ? 10.173  10.197  10.615 1.00 27.99 ?  89   LEU A HD11 1 
ATOM   1118  H HD12 . LEU A 1 123 ? 10.094  10.301  12.198 1.00 27.99 ?  89   LEU A HD12 1 
ATOM   1119  H HD13 . LEU A 1 123 ? 11.349  9.613   11.508 1.00 27.99 ?  89   LEU A HD13 1 
ATOM   1120  H HD21 . LEU A 1 123 ? 10.156  8.119   9.511  1.00 36.52 ?  89   LEU A HD21 1 
ATOM   1121  H HD22 . LEU A 1 123 ? 11.009  7.197   10.482 1.00 36.52 ?  89   LEU A HD22 1 
ATOM   1122  H HD23 . LEU A 1 123 ? 9.490   6.842   10.180 1.00 36.52 ?  89   LEU A HD23 1 
ATOM   1123  N N    . LYS A 1 124 ? 9.339   5.675   15.316 1.00 15.79 ?  90   LYS A N    1 
ATOM   1124  C CA   . LYS A 1 124 ? 9.839   4.774   16.336 1.00 16.18 ?  90   LYS A CA   1 
ATOM   1125  C C    . LYS A 1 124 ? 9.072   3.461   16.363 1.00 17.73 ?  90   LYS A C    1 
ATOM   1126  O O    . LYS A 1 124 ? 9.677   2.388   16.527 1.00 19.35 ?  90   LYS A O    1 
ATOM   1127  C CB   . LYS A 1 124 ? 9.764   5.474   17.695 1.00 19.79 ?  90   LYS A CB   1 
ATOM   1128  C CG   . LYS A 1 124 ? 10.297  4.682   18.826 1.00 24.32 ?  90   LYS A CG   1 
ATOM   1129  H H    . LYS A 1 124 ? 8.771   6.255   15.599 1.00 18.95 ?  90   LYS A H    1 
ATOM   1130  H HA   . LYS A 1 124 ? 10.766  4.558   16.146 1.00 19.41 ?  90   LYS A HA   1 
ATOM   1131  H HB2  . LYS A 1 124 ? 10.276  6.297   17.647 1.00 23.75 ?  90   LYS A HB2  1 
ATOM   1132  H HB3  . LYS A 1 124 ? 8.835   5.673   17.889 1.00 23.75 ?  90   LYS A HB3  1 
ATOM   1133  H HG2  . LYS A 1 124 ? 10.049  5.100   19.666 1.00 29.18 ?  90   LYS A HG2  1 
ATOM   1134  H HG3  . LYS A 1 124 ? 9.947   3.779   18.789 1.00 29.18 ?  90   LYS A HG3  1 
ATOM   1135  N N    . ASN A 1 125 ? 7.745   3.490   16.245 1.00 16.47 ?  91   ASN A N    1 
ATOM   1136  C CA   . ASN A 1 125 ? 6.952   2.267   16.253 1.00 14.85 ?  91   ASN A CA   1 
ATOM   1137  C C    . ASN A 1 125 ? 5.754   2.472   15.330 1.00 16.69 ?  91   ASN A C    1 
ATOM   1138  O O    . ASN A 1 125 ? 4.764   3.102   15.728 1.00 15.92 ?  91   ASN A O    1 
ATOM   1139  C CB   . ASN A 1 125 ? 6.476   1.920   17.653 1.00 15.26 ?  91   ASN A CB   1 
ATOM   1140  C CG   . ASN A 1 125 ? 5.841   0.566   17.707 1.00 19.62 ?  91   ASN A CG   1 
ATOM   1141  O OD1  . ASN A 1 125 ? 5.422   0.034   16.671 1.00 18.62 ?  91   ASN A OD1  1 
ATOM   1142  N ND2  . ASN A 1 125 ? 5.817   -0.035  18.885 1.00 26.62 ?  91   ASN A ND2  1 
ATOM   1143  H H    . ASN A 1 125 ? 7.281   4.209   16.158 1.00 19.77 ?  91   ASN A H    1 
ATOM   1144  H HA   . ASN A 1 125 ? 7.503   1.547   15.910 1.00 17.82 ?  91   ASN A HA   1 
ATOM   1145  H HB2  . ASN A 1 125 ? 7.234   1.924   18.258 1.00 18.32 ?  91   ASN A HB2  1 
ATOM   1146  H HB3  . ASN A 1 125 ? 5.820   2.575   17.939 1.00 18.32 ?  91   ASN A HB3  1 
ATOM   1147  H HD21 . ASN A 1 125 ? 5.462   -0.814  18.963 1.00 31.94 ?  91   ASN A HD21 1 
ATOM   1148  H HD22 . ASN A 1 125 ? 6.157   0.354   19.573 1.00 31.94 ?  91   ASN A HD22 1 
ATOM   1149  N N    . ASN A 1 126 ? 5.832   1.947   14.112 1.00 18.08 ?  92   ASN A N    1 
ATOM   1150  C CA   . ASN A 1 126 ? 4.783   2.198   13.131 1.00 18.80 ?  92   ASN A CA   1 
ATOM   1151  C C    . ASN A 1 126 ? 3.501   1.442   13.449 1.00 19.21 ?  92   ASN A C    1 
ATOM   1152  O O    . ASN A 1 126 ? 2.459   1.740   12.840 1.00 21.11 ?  92   ASN A O    1 
ATOM   1153  C CB   . ASN A 1 126 ? 5.262   1.892   11.706 1.00 22.62 ?  92   ASN A CB   1 
ATOM   1154  C CG   . ASN A 1 126 ? 5.744   0.478   11.532 1.00 38.75 ?  92   ASN A CG   1 
ATOM   1155  O OD1  . ASN A 1 126 ? 5.155   -0.464  12.053 1.00 38.22 ?  92   ASN A OD1  1 
ATOM   1156  N ND2  . ASN A 1 126 ? 6.826   0.314   10.769 1.00 56.65 ?  92   ASN A ND2  1 
ATOM   1157  H H    . ASN A 1 126 ? 6.474   1.448   13.832 1.00 21.70 ?  92   ASN A H    1 
ATOM   1158  H HA   . ASN A 1 126 ? 4.575   3.145   13.141 1.00 22.56 ?  92   ASN A HA   1 
ATOM   1159  H HB2  . ASN A 1 126 ? 4.527   2.034   11.090 1.00 27.14 ?  92   ASN A HB2  1 
ATOM   1160  H HB3  . ASN A 1 126 ? 5.998   2.486   11.488 1.00 27.14 ?  92   ASN A HB3  1 
ATOM   1161  H HD21 . ASN A 1 126 ? 7.206   0.997   10.409 1.00 67.98 ?  92   ASN A HD21 1 
ATOM   1162  H HD22 . ASN A 1 126 ? 7.143   -0.474  10.636 1.00 67.98 ?  92   ASN A HD22 1 
ATOM   1163  N N    . LYS A 1 127 ? 3.532   0.540   14.416 1.00 17.68 ?  93   LYS A N    1 
ATOM   1164  C CA   . LYS A 1 127 ? 2.348   -0.198  14.834 1.00 16.29 ?  93   LYS A CA   1 
ATOM   1165  C C    . LYS A 1 127 ? 1.524   0.535   15.890 1.00 16.00 ?  93   LYS A C    1 
ATOM   1166  O O    . LYS A 1 127 ? 0.371   0.169   16.090 1.00 15.46 ?  93   LYS A O    1 
ATOM   1167  C CB   . LYS A 1 127 ? 2.745   -1.571  15.370 1.00 17.31 ?  93   LYS A CB   1 
ATOM   1168  C CG   . LYS A 1 127 ? 3.459   -2.475  14.350 1.00 25.40 ?  93   LYS A CG   1 
ATOM   1169  C CD   . LYS A 1 127 ? 3.556   -3.897  14.893 1.00 40.40 ?  93   LYS A CD   1 
ATOM   1170  C CE   . LYS A 1 127 ? 4.045   -4.870  13.831 1.00 48.03 ?  93   LYS A CE   1 
ATOM   1171  N NZ   . LYS A 1 127 ? 4.438   -6.179  14.434 1.00 50.31 ?  93   LYS A NZ   1 
ATOM   1172  H H    . LYS A 1 127 ? 4.240   0.331   14.856 1.00 21.22 ?  93   LYS A H    1 
ATOM   1173  H HA   . LYS A 1 127 ? 1.781   -0.333  14.058 1.00 19.54 ?  93   LYS A HA   1 
ATOM   1174  H HB2  . LYS A 1 127 ? 3.346   -1.447  16.121 1.00 20.77 ?  93   LYS A HB2  1 
ATOM   1175  H HB3  . LYS A 1 127 ? 1.943   -2.033  15.659 1.00 20.77 ?  93   LYS A HB3  1 
ATOM   1176  H HG2  . LYS A 1 127 ? 2.957   -2.493  13.520 1.00 30.48 ?  93   LYS A HG2  1 
ATOM   1177  H HG3  . LYS A 1 127 ? 4.355   -2.142  14.188 1.00 30.48 ?  93   LYS A HG3  1 
ATOM   1178  H HD2  . LYS A 1 127 ? 4.182   -3.915  15.634 1.00 48.48 ?  93   LYS A HD2  1 
ATOM   1179  H HD3  . LYS A 1 127 ? 2.680   -4.187  15.192 1.00 48.48 ?  93   LYS A HD3  1 
ATOM   1180  H HE2  . LYS A 1 127 ? 3.336   -5.029  13.189 1.00 57.64 ?  93   LYS A HE2  1 
ATOM   1181  H HE3  . LYS A 1 127 ? 4.820   -4.495  13.383 1.00 57.64 ?  93   LYS A HE3  1 
ATOM   1182  H HZ1  . LYS A 1 127 ? 4.761   -6.720  13.805 1.00 60.37 ?  93   LYS A HZ1  1 
ATOM   1183  H HZ2  . LYS A 1 127 ? 5.063   -6.053  15.055 1.00 60.37 ?  93   LYS A HZ2  1 
ATOM   1184  H HZ3  . LYS A 1 127 ? 3.730   -6.566  14.811 1.00 60.37 ?  93   LYS A HZ3  1 
ATOM   1185  N N    . ALA A 1 128 ? 2.070   1.567   16.519 1.00 15.33 ?  94   ALA A N    1 
ATOM   1186  C CA   . ALA A 1 128 ? 1.299   2.343   17.503 1.00 13.24 ?  94   ALA A CA   1 
ATOM   1187  C C    . ALA A 1 128 ? 0.172   3.048   16.796 1.00 14.69 ?  94   ALA A C    1 
ATOM   1188  O O    . ALA A 1 128 ? 0.397   3.654   15.757 1.00 17.56 ?  94   ALA A O    1 
ATOM   1189  C CB   . ALA A 1 128 ? 2.210   3.369   18.162 1.00 16.06 ?  94   ALA A CB   1 
ATOM   1190  H H    . ALA A 1 128 ? 2.876   1.843   16.401 1.00 18.39 ?  94   ALA A H    1 
ATOM   1191  H HA   . ALA A 1 128 ? 0.935   1.759   18.187 1.00 15.89 ?  94   ALA A HA   1 
ATOM   1192  H HB1  . ALA A 1 128 ? 1.677   3.943   18.734 1.00 19.28 ?  94   ALA A HB1  1 
ATOM   1193  H HB2  . ALA A 1 128 ? 2.879   2.906   18.689 1.00 19.28 ?  94   ALA A HB2  1 
ATOM   1194  H HB3  . ALA A 1 128 ? 2.641   3.898   17.472 1.00 19.28 ?  94   ALA A HB3  1 
ATOM   1195  N N    . LYS A 1 129 ? -1.033  2.994   17.356 1.00 12.26 ?  95   LYS A N    1 
ATOM   1196  C CA   . LYS A 1 129 ? -2.157  3.732   16.797 1.00 12.38 ?  95   LYS A CA   1 
ATOM   1197  C C    . LYS A 1 129 ? -2.291  5.089   17.465 1.00 11.46 ?  95   LYS A C    1 
ATOM   1198  O O    . LYS A 1 129 ? -2.289  5.164   18.696 1.00 13.83 ?  95   LYS A O    1 
ATOM   1199  C CB   . LYS A 1 129 ? -3.467  2.956   16.971 1.00 13.22 ?  95   LYS A CB   1 
ATOM   1200  C CG   . LYS A 1 129 ? -3.516  1.644   16.187 1.00 13.35 ?  95   LYS A CG   1 
ATOM   1201  C CD   . LYS A 1 129 ? -3.424  1.794   14.691 1.00 14.26 ?  95   LYS A CD   1 
ATOM   1202  C CE   . LYS A 1 129 ? -3.671  0.457   13.976 1.00 14.50 ?  95   LYS A CE   1 
ATOM   1203  N NZ   . LYS A 1 129 ? -3.753  0.636   12.517 1.00 16.82 ?  95   LYS A NZ   1 
ATOM   1204  H H    . LYS A 1 129 ? -1.223  2.537   18.060 1.00 14.71 ?  95   LYS A H    1 
ATOM   1205  H HA   . LYS A 1 129 ? -1.990  3.865   15.851 1.00 14.86 ?  95   LYS A HA   1 
ATOM   1206  H HB2  . LYS A 1 129 ? -3.582  2.744   17.910 1.00 15.86 ?  95   LYS A HB2  1 
ATOM   1207  H HB3  . LYS A 1 129 ? -4.201  3.511   16.664 1.00 15.86 ?  95   LYS A HB3  1 
ATOM   1208  H HG2  . LYS A 1 129 ? -2.772  1.089   16.470 1.00 16.02 ?  95   LYS A HG2  1 
ATOM   1209  H HG3  . LYS A 1 129 ? -4.355  1.199   16.383 1.00 16.02 ?  95   LYS A HG3  1 
ATOM   1210  H HD2  . LYS A 1 129 ? -4.092  2.429   14.389 1.00 17.11 ?  95   LYS A HD2  1 
ATOM   1211  H HD3  . LYS A 1 129 ? -2.537  2.107   14.453 1.00 17.11 ?  95   LYS A HD3  1 
ATOM   1212  H HE2  . LYS A 1 129 ? -2.940  -0.151  14.169 1.00 17.40 ?  95   LYS A HE2  1 
ATOM   1213  H HE3  . LYS A 1 129 ? -4.508  0.077   14.285 1.00 17.40 ?  95   LYS A HE3  1 
ATOM   1214  H HZ1  . LYS A 1 129 ? -4.445  1.157   12.313 1.00 20.18 ?  95   LYS A HZ1  1 
ATOM   1215  H HZ2  . LYS A 1 129 ? -3.007  1.014   12.214 1.00 20.18 ?  95   LYS A HZ2  1 
ATOM   1216  H HZ3  . LYS A 1 129 ? -3.859  -0.153  12.119 1.00 20.18 ?  95   LYS A HZ3  1 
ATOM   1217  N N    . VAL A 1 130 ? -2.462  6.123   16.644 1.00 11.77 ?  96   VAL A N    1 
ATOM   1218  C CA   . VAL A 1 130 ? -2.484  7.510   17.098 1.00 11.72 ?  96   VAL A CA   1 
ATOM   1219  C C    . VAL A 1 130 ? -3.802  8.136   16.691 1.00 12.12 ?  96   VAL A C    1 
ATOM   1220  O O    . VAL A 1 130 ? -4.150  8.181   15.496 1.00 13.14 ?  96   VAL A O    1 
ATOM   1221  C CB   . VAL A 1 130 ? -1.317  8.300   16.509 1.00 12.17 ?  96   VAL A CB   1 
ATOM   1222  C CG1  . VAL A 1 130 ? -1.352  9.748   16.994 1.00 14.71 ?  96   VAL A CG1  1 
ATOM   1223  C CG2  . VAL A 1 130 ? 0.024   7.720   16.895 1.00 13.92 ?  96   VAL A CG2  1 
ATOM   1224  H H    . VAL A 1 130 ? -2.571  6.042   15.795 1.00 14.13 ?  96   VAL A H    1 
ATOM   1225  H HA   . VAL A 1 130 ? -2.430  7.528   18.066 1.00 14.06 ?  96   VAL A HA   1 
ATOM   1226  H HB   . VAL A 1 130 ? -1.413  8.257   15.544 1.00 14.60 ?  96   VAL A HB   1 
ATOM   1227  H HG11 . VAL A 1 130 ? -0.516  10.180  16.758 1.00 17.65 ?  96   VAL A HG11 1 
ATOM   1228  H HG12 . VAL A 1 130 ? -2.093  10.206  16.567 1.00 17.65 ?  96   VAL A HG12 1 
ATOM   1229  H HG13 . VAL A 1 130 ? -1.469  9.756   17.957 1.00 17.65 ?  96   VAL A HG13 1 
ATOM   1230  H HG21 . VAL A 1 130 ? 0.722   8.191   16.413 1.00 16.70 ?  96   VAL A HG21 1 
ATOM   1231  H HG22 . VAL A 1 130 ? 0.151   7.828   17.850 1.00 16.70 ?  96   VAL A HG22 1 
ATOM   1232  H HG23 . VAL A 1 130 ? 0.039   6.778   16.663 1.00 16.70 ?  96   VAL A HG23 1 
ATOM   1233  N N    . LEU A 1 131 ? -4.542  8.634   17.685 1.00 11.29 ?  97   LEU A N    1 
ATOM   1234  C CA   . LEU A 1 131 ? -5.813  9.305   17.473 1.00 11.92 ?  97   LEU A CA   1 
ATOM   1235  C C    . LEU A 1 131 ? -5.719  10.807  17.684 1.00 10.08 ?  97   LEU A C    1 
ATOM   1236  O O    . LEU A 1 131 ? -5.019  11.285  18.589 1.00 12.31 ?  97   LEU A O    1 
ATOM   1237  C CB   . LEU A 1 131 ? -6.880  8.776   18.428 1.00 12.60 ?  97   LEU A CB   1 
ATOM   1238  C CG   . LEU A 1 131 ? -7.072  7.264   18.446 1.00 10.83 ?  97   LEU A CG   1 
ATOM   1239  C CD1  . LEU A 1 131 ? -8.184  6.909   19.374 1.00 13.37 ?  97   LEU A CD1  1 
ATOM   1240  C CD2  . LEU A 1 131 ? -7.375  6.683   17.055 1.00 13.44 ?  97   LEU A CD2  1 
ATOM   1241  H H    . LEU A 1 131 ? -4.315  8.592   18.514 1.00 13.55 ?  97   LEU A H    1 
ATOM   1242  H HA   . LEU A 1 131 ? -6.066  9.143   16.551 1.00 14.30 ?  97   LEU A HA   1 
ATOM   1243  H HB2  . LEU A 1 131 ? -6.639  9.045   19.329 1.00 15.12 ?  97   LEU A HB2  1 
ATOM   1244  H HB3  . LEU A 1 131 ? -7.730  9.170   18.180 1.00 15.12 ?  97   LEU A HB3  1 
ATOM   1245  H HG   . LEU A 1 131 ? -6.239  6.869   18.746 1.00 12.99 ?  97   LEU A HG   1 
ATOM   1246  H HD11 . LEU A 1 131 ? -8.376  5.963   19.289 1.00 16.04 ?  97   LEU A HD11 1 
ATOM   1247  H HD12 . LEU A 1 131 ? -7.913  7.111   20.283 1.00 16.04 ?  97   LEU A HD12 1 
ATOM   1248  H HD13 . LEU A 1 131 ? -8.969  7.429   19.139 1.00 16.04 ?  97   LEU A HD13 1 
ATOM   1249  H HD21 . LEU A 1 131 ? -7.429  5.717   17.121 1.00 16.12 ?  97   LEU A HD21 1 
ATOM   1250  H HD22 . LEU A 1 131 ? -8.220  7.041   16.740 1.00 16.12 ?  97   LEU A HD22 1 
ATOM   1251  H HD23 . LEU A 1 131 ? -6.662  6.933   16.446 1.00 16.12 ?  97   LEU A HD23 1 
ATOM   1252  N N    . TYR A 1 132 ? -6.447  11.543  16.859 1.00 10.19 ?  98   TYR A N    1 
ATOM   1253  C CA   . TYR A 1 132 ? -6.551  12.990  16.935 1.00 11.54 ?  98   TYR A CA   1 
ATOM   1254  C C    . TYR A 1 132 ? -7.778  13.379  17.740 1.00 11.42 ?  98   TYR A C    1 
ATOM   1255  O O    . TYR A 1 132 ? -8.903  13.108  17.320 1.00 10.79 ?  98   TYR A O    1 
ATOM   1256  C CB   . TYR A 1 132 ? -6.706  13.575  15.542 1.00 12.21 ?  98   TYR A CB   1 
ATOM   1257  C CG   . TYR A 1 132 ? -6.724  15.080  15.432 1.00 11.27 ?  98   TYR A CG   1 
ATOM   1258  C CD1  . TYR A 1 132 ? -5.732  15.862  15.987 1.00 12.83 ?  98   TYR A CD1  1 
ATOM   1259  C CD2  . TYR A 1 132 ? -7.722  15.716  14.720 1.00 11.63 ?  98   TYR A CD2  1 
ATOM   1260  C CE1  . TYR A 1 132 ? -5.720  17.222  15.807 1.00 10.90 ?  98   TYR A CE1  1 
ATOM   1261  C CE2  . TYR A 1 132 ? -7.712  17.096  14.551 1.00 11.56 ?  98   TYR A CE2  1 
ATOM   1262  C CZ   . TYR A 1 132 ? -6.697  17.829  15.090 1.00 11.17 ?  98   TYR A CZ   1 
ATOM   1263  O OH   . TYR A 1 132 ? -6.602  19.211  14.965 1.00 12.76 ?  98   TYR A OH   1 
ATOM   1264  H H    . TYR A 1 132 ? -6.913  11.211  16.217 1.00 12.23 ?  98   TYR A H    1 
ATOM   1265  H HA   . TYR A 1 132 ? -5.755  13.333  17.370 1.00 13.85 ?  98   TYR A HA   1 
ATOM   1266  H HB2  . TYR A 1 132 ? -5.965  13.261  15.001 1.00 14.65 ?  98   TYR A HB2  1 
ATOM   1267  H HB3  . TYR A 1 132 ? -7.545  13.255  15.174 1.00 14.65 ?  98   TYR A HB3  1 
ATOM   1268  H HD1  . TYR A 1 132 ? -5.061  15.461  16.491 1.00 15.39 ?  98   TYR A HD1  1 
ATOM   1269  H HD2  . TYR A 1 132 ? -8.411  15.214  14.347 1.00 13.95 ?  98   TYR A HD2  1 
ATOM   1270  H HE1  . TYR A 1 132 ? -5.036  17.731  16.179 1.00 13.08 ?  98   TYR A HE1  1 
ATOM   1271  H HE2  . TYR A 1 132 ? -8.393  17.515  14.075 1.00 13.87 ?  98   TYR A HE2  1 
ATOM   1272  H HH   . TYR A 1 132 ? -7.241  19.503  14.505 1.00 15.31 ?  98   TYR A HH   1 
ATOM   1273  N N    . TYR A 1 133 ? -7.581  14.108  18.833 1.00 11.13 ?  99   TYR A N    1 
ATOM   1274  C CA   . TYR A 1 133 ? -8.718  14.608  19.618 1.00 11.01 ?  99   TYR A CA   1 
ATOM   1275  C C    . TYR A 1 133 ? -9.500  15.641  18.816 1.00 10.27 ?  99   TYR A C    1 
ATOM   1276  O O    . TYR A 1 133 ? -8.935  16.538  18.187 1.00 10.47 ?  99   TYR A O    1 
ATOM   1277  C CB   . TYR A 1 133 ? -8.173  15.279  20.867 1.00 10.43 ?  99   TYR A CB   1 
ATOM   1278  C CG   . TYR A 1 133 ? -9.205  15.959  21.788 1.00 10.23 ?  99   TYR A CG   1 
ATOM   1279  C CD1  . TYR A 1 133 ? -9.587  17.269  21.554 1.00 10.86 ?  99   TYR A CD1  1 
ATOM   1280  C CD2  . TYR A 1 133 ? -9.776  15.289  22.867 1.00 10.32 ?  99   TYR A CD2  1 
ATOM   1281  C CE1  . TYR A 1 133 ? -10.487 17.908  22.373 1.00 11.29 ?  99   TYR A CE1  1 
ATOM   1282  C CE2  . TYR A 1 133 ? -10.688 15.944  23.708 1.00 10.48 ?  99   TYR A CE2  1 
ATOM   1283  C CZ   . TYR A 1 133 ? -11.030 17.223  23.429 1.00 10.59 ?  99   TYR A CZ   1 
ATOM   1284  O OH   . TYR A 1 133 ? -11.932 17.915  24.224 1.00 11.28 ?  99   TYR A OH   1 
ATOM   1285  H H    . TYR A 1 133 ? -6.809  14.328  19.143 1.00 13.35 ?  99   TYR A H    1 
ATOM   1286  H HA   . TYR A 1 133 ? -9.313  13.879  19.854 1.00 13.21 ?  99   TYR A HA   1 
ATOM   1287  H HB2  . TYR A 1 133 ? -7.719  14.605  21.397 1.00 12.52 ?  99   TYR A HB2  1 
ATOM   1288  H HB3  . TYR A 1 133 ? -7.543  15.963  20.591 1.00 12.52 ?  99   TYR A HB3  1 
ATOM   1289  H HD1  . TYR A 1 133 ? -9.227  17.726  20.828 1.00 13.03 ?  99   TYR A HD1  1 
ATOM   1290  H HD2  . TYR A 1 133 ? -9.551  14.401  23.031 1.00 12.39 ?  99   TYR A HD2  1 
ATOM   1291  H HE1  . TYR A 1 133 ? -10.725 18.793  22.213 1.00 13.55 ?  99   TYR A HE1  1 
ATOM   1292  H HE2  . TYR A 1 133 ? -11.051 15.506  24.445 1.00 12.57 ?  99   TYR A HE2  1 
ATOM   1293  H HH   . TYR A 1 133 ? -12.246 17.405  24.813 1.00 13.53 ?  99   TYR A HH   1 
ATOM   1294  N N    . ARG A 1 134 ? -10.831 15.546  18.891 1.00 9.91  ?  100  ARG A N    1 
ATOM   1295  C CA   . ARG A 1 134 ? -11.651 16.617  18.359 1.00 11.13 ?  100  ARG A CA   1 
ATOM   1296  C C    . ARG A 1 134 ? -12.895 16.753  19.222 1.00 10.35 ?  100  ARG A C    1 
ATOM   1297  O O    . ARG A 1 134 ? -13.663 15.809  19.387 1.00 11.74 ?  100  ARG A O    1 
ATOM   1298  C CB   . ARG A 1 134 ? -12.076 16.390  16.897 1.00 10.78 ?  100  ARG A CB   1 
ATOM   1299  C CG   . ARG A 1 134 ? -12.486 17.684  16.221 1.00 12.47 ?  100  ARG A CG   1 
ATOM   1300  C CD   . ARG A 1 134 ? -11.264 18.491  15.749 1.00 12.23 ?  100  ARG A CD   1 
ATOM   1301  N NE   . ARG A 1 134 ? -11.651 19.599  14.889 1.00 12.27 ?  100  ARG A NE   1 
ATOM   1302  C CZ   . ARG A 1 134 ? -11.514 20.901  15.132 1.00 12.78 ?  100  ARG A CZ   1 
ATOM   1303  N NH1  . ARG A 1 134 ? -11.116 21.371  16.308 1.00 12.21 ?  100  ARG A NH1  1 
ATOM   1304  N NH2  . ARG A 1 134 ? -11.780 21.775  14.174 1.00 12.20 ?  100  ARG A NH2  1 
ATOM   1305  H H    . ARG A 1 134 ? -11.262 14.888  19.237 1.00 11.89 ?  100  ARG A H    1 
ATOM   1306  H HA   . ARG A 1 134 ? -11.129 17.434  18.393 1.00 13.35 ?  100  ARG A HA   1 
ATOM   1307  H HB2  . ARG A 1 134 ? -11.332 16.012  16.403 1.00 12.94 ?  100  ARG A HB2  1 
ATOM   1308  H HB3  . ARG A 1 134 ? -12.832 15.783  16.875 1.00 12.94 ?  100  ARG A HB3  1 
ATOM   1309  H HG2  . ARG A 1 134 ? -13.034 17.482  15.446 1.00 14.96 ?  100  ARG A HG2  1 
ATOM   1310  H HG3  . ARG A 1 134 ? -12.987 18.229  16.848 1.00 14.96 ?  100  ARG A HG3  1 
ATOM   1311  H HD2  . ARG A 1 134 ? -10.801 18.852  16.522 1.00 14.68 ?  100  ARG A HD2  1 
ATOM   1312  H HD3  . ARG A 1 134 ? -10.670 17.910  15.249 1.00 14.68 ?  100  ARG A HD3  1 
ATOM   1313  H HE   . ARG A 1 134 ? -12.009 19.389  14.136 1.00 14.73 ?  100  ARG A HE   1 
ATOM   1314  H HH11 . ARG A 1 134 ? -10.935 20.828  16.949 1.00 14.65 ?  100  ARG A HH11 1 
ATOM   1315  H HH12 . ARG A 1 134 ? -11.040 22.219  16.428 1.00 14.65 ?  100  ARG A HH12 1 
ATOM   1316  H HH21 . ARG A 1 134 ? -12.039 21.500  13.401 1.00 14.64 ?  100  ARG A HH21 1 
ATOM   1317  H HH22 . ARG A 1 134 ? -11.694 22.617  14.325 1.00 14.64 ?  100  ARG A HH22 1 
ATOM   1318  N N    . ASN A 1 135 ? -13.127 17.960  19.709 1.00 10.15 ?  101  ASN A N    1 
ATOM   1319  C CA   . ASN A 1 135 ? -14.339 18.251  20.469 1.00 10.42 ?  101  ASN A CA   1 
ATOM   1320  C C    . ASN A 1 135 ? -15.460 18.639  19.506 1.00 9.72  ?  101  ASN A C    1 
ATOM   1321  O O    . ASN A 1 135 ? -15.269 19.520  18.662 1.00 11.06 ?  101  ASN A O    1 
ATOM   1322  C CB   . ASN A 1 135 ? -14.068 19.392  21.453 1.00 9.84  ?  101  ASN A CB   1 
ATOM   1323  C CG   . ASN A 1 135 ? -15.049 19.415  22.594 1.00 10.55 ?  101  ASN A CG   1 
ATOM   1324  O OD1  . ASN A 1 135 ? -16.233 19.655  22.381 1.00 10.47 ?  101  ASN A OD1  1 
ATOM   1325  N ND2  . ASN A 1 135 ? -14.596 19.084  23.770 1.00 11.44 ?  101  ASN A ND2  1 
ATOM   1326  H H    . ASN A 1 135 ? -12.598 18.632  19.614 1.00 12.18 ?  101  ASN A H    1 
ATOM   1327  H HA   . ASN A 1 135 ? -14.620 17.468  20.967 1.00 12.50 ?  101  ASN A HA   1 
ATOM   1328  H HB2  . ASN A 1 135 ? -13.178 19.287  21.824 1.00 11.81 ?  101  ASN A HB2  1 
ATOM   1329  H HB3  . ASN A 1 135 ? -14.134 20.238  20.983 1.00 11.81 ?  101  ASN A HB3  1 
ATOM   1330  H HD21 . ASN A 1 135 ? -15.124 19.084  24.450 1.00 13.73 ?  101  ASN A HD21 1 
ATOM   1331  H HD22 . ASN A 1 135 ? -13.770 18.866  23.868 1.00 13.73 ?  101  ASN A HD22 1 
ATOM   1332  N N    . VAL A 1 136 ? -16.620 17.994  19.646 1.00 9.98  ?  102  VAL A N    1 
ATOM   1333  C CA   . VAL A 1 136 ? -17.719 18.194  18.699 1.00 10.62 ?  102  VAL A CA   1 
ATOM   1334  C C    . VAL A 1 136 ? -18.435 19.500  18.909 1.00 10.15 ?  102  VAL A C    1 
ATOM   1335  O O    . VAL A 1 136 ? -19.087 19.987  17.969 1.00 12.23 ?  102  VAL A O    1 
ATOM   1336  C CB   . VAL A 1 136 ? -18.677 16.991  18.718 1.00 11.30 ?  102  VAL A CB   1 
ATOM   1337  C CG1  . VAL A 1 136 ? -19.544 16.937  19.967 1.00 12.01 ?  102  VAL A CG1  1 
ATOM   1338  C CG2  . VAL A 1 136 ? -19.541 16.941  17.425 1.00 13.54 ?  102  VAL A CG2  1 
ATOM   1339  H H    . VAL A 1 136 ? -16.797 17.438  20.278 1.00 11.98 ?  102  VAL A H    1 
ATOM   1340  H HA   . VAL A 1 136 ? -17.349 18.240  17.804 1.00 12.75 ?  102  VAL A HA   1 
ATOM   1341  H HB   . VAL A 1 136 ? -18.125 16.194  18.743 1.00 13.56 ?  102  VAL A HB   1 
ATOM   1342  H HG11 . VAL A 1 136 ? -20.110 16.150  19.924 1.00 14.41 ?  102  VAL A HG11 1 
ATOM   1343  H HG12 . VAL A 1 136 ? -18.970 16.890  20.748 1.00 14.41 ?  102  VAL A HG12 1 
ATOM   1344  H HG13 . VAL A 1 136 ? -20.092 17.737  20.007 1.00 14.41 ?  102  VAL A HG13 1 
ATOM   1345  H HG21 . VAL A 1 136 ? -20.047 16.114  17.415 1.00 16.25 ?  102  VAL A HG21 1 
ATOM   1346  H HG22 . VAL A 1 136 ? -20.147 17.699  17.421 1.00 16.25 ?  102  VAL A HG22 1 
ATOM   1347  H HG23 . VAL A 1 136 ? -18.956 16.981  16.652 1.00 16.25 ?  102  VAL A HG23 1 
ATOM   1348  N N    . VAL A 1 137 ? -18.340 20.128  20.081 1.00 10.48 ?  103  VAL A N    1 
ATOM   1349  C CA   . VAL A 1 137 ? -19.049 21.383  20.322 1.00 11.40 ?  103  VAL A CA   1 
ATOM   1350  C C    . VAL A 1 137 ? -18.295 22.495  21.010 1.00 10.34 ?  103  VAL A C    1 
ATOM   1351  O O    . VAL A 1 137 ? -18.700 23.645  20.920 1.00 11.96 ?  103  VAL A O    1 
ATOM   1352  C CB   . VAL A 1 137 ? -20.375 21.190  21.105 1.00 11.49 ?  103  VAL A CB   1 
ATOM   1353  C CG1  . VAL A 1 137 ? -21.506 20.671  20.238 1.00 12.68 ?  103  VAL A CG1  1 
ATOM   1354  C CG2  . VAL A 1 137 ? -20.189 20.351  22.381 1.00 11.44 ?  103  VAL A CG2  1 
ATOM   1355  H H    . VAL A 1 137 ? -17.874 19.848  20.747 1.00 12.57 ?  103  VAL A H    1 
ATOM   1356  H HA   . VAL A 1 137 ? -19.180 21.677  19.407 1.00 13.68 ?  103  VAL A HA   1 
ATOM   1357  H HB   . VAL A 1 137 ? -20.647 22.075  21.396 1.00 13.78 ?  103  VAL A HB   1 
ATOM   1358  H HG11 . VAL A 1 137 ? -22.290 20.530  20.792 1.00 15.22 ?  103  VAL A HG11 1 
ATOM   1359  H HG12 . VAL A 1 137 ? -21.701 21.325  19.549 1.00 15.22 ?  103  VAL A HG12 1 
ATOM   1360  H HG13 . VAL A 1 137 ? -21.234 19.833  19.832 1.00 15.22 ?  103  VAL A HG13 1 
ATOM   1361  H HG21 . VAL A 1 137 ? -21.004 20.390  22.906 1.00 13.73 ?  103  VAL A HG21 1 
ATOM   1362  H HG22 . VAL A 1 137 ? -20.000 19.433  22.131 1.00 13.73 ?  103  VAL A HG22 1 
ATOM   1363  H HG23 . VAL A 1 137 ? -19.449 20.714  22.893 1.00 13.73 ?  103  VAL A HG23 1 
ATOM   1364  N N    . ILE A 1 138 ? -17.216 22.219  21.729 1.00 11.31 ?  104  ILE A N    1 
ATOM   1365  C CA   . ILE A 1 138 ? -16.503 23.269  22.459 1.00 11.45 ?  104  ILE A CA   1 
ATOM   1366  C C    . ILE A 1 138 ? -15.353 23.803  21.611 1.00 10.52 ?  104  ILE A C    1 
ATOM   1367  O O    . ILE A 1 138 ? -14.506 23.029  21.149 1.00 11.51 ?  104  ILE A O    1 
ATOM   1368  C CB   . ILE A 1 138 ? -15.975 22.729  23.810 1.00 10.57 ?  104  ILE A CB   1 
ATOM   1369  C CG1  . ILE A 1 138 ? -17.103 22.192  24.687 1.00 12.11 ?  104  ILE A CG1  1 
ATOM   1370  C CG2  . ILE A 1 138 ? -15.282 23.879  24.543 1.00 10.60 ?  104  ILE A CG2  1 
ATOM   1371  C CD1  . ILE A 1 138 ? -16.668 21.447  25.908 1.00 11.69 ?  104  ILE A CD1  1 
ATOM   1372  H H    . ILE A 1 138 ? -16.875 21.434  21.813 1.00 13.57 ?  104  ILE A H    1 
ATOM   1373  H HA   . ILE A 1 138 ? -17.117 24.002  22.622 1.00 13.75 ?  104  ILE A HA   1 
ATOM   1374  H HB   . ILE A 1 138 ? -15.364 21.997  23.630 1.00 12.69 ?  104  ILE A HB   1 
ATOM   1375  H HG12 . ILE A 1 138 ? -17.643 22.941  24.982 1.00 14.53 ?  104  ILE A HG12 1 
ATOM   1376  H HG13 . ILE A 1 138 ? -17.640 21.584  24.154 1.00 14.53 ?  104  ILE A HG13 1 
ATOM   1377  H HG21 . ILE A 1 138 ? -15.042 23.585  25.436 1.00 12.72 ?  104  ILE A HG21 1 
ATOM   1378  H HG22 . ILE A 1 138 ? -14.485 24.131  24.052 1.00 12.72 ?  104  ILE A HG22 1 
ATOM   1379  H HG23 . ILE A 1 138 ? -15.891 24.632  24.596 1.00 12.72 ?  104  ILE A HG23 1 
ATOM   1380  H HD11 . ILE A 1 138 ? -17.453 21.112  26.370 1.00 14.03 ?  104  ILE A HD11 1 
ATOM   1381  H HD12 . ILE A 1 138 ? -16.101 20.706  25.642 1.00 14.03 ?  104  ILE A HD12 1 
ATOM   1382  H HD13 . ILE A 1 138 ? -16.176 22.049  26.487 1.00 14.03 ?  104  ILE A HD13 1 
ATOM   1383  N N    . ASN A 1 139 ? -15.271 25.122  21.489 1.00 10.03 ?  105  ASN A N    1 
ATOM   1384  C CA   . ASN A 1 139 ? -14.272 25.824  20.675 1.00 10.59 ?  105  ASN A CA   1 
ATOM   1385  C C    . ASN A 1 139 ? -13.055 26.172  21.536 1.00 11.76 ?  105  ASN A C    1 
ATOM   1386  O O    . ASN A 1 139 ? -12.782 27.330  21.829 1.00 12.17 ?  105  ASN A O    1 
ATOM   1387  C CB   . ASN A 1 139 ? -14.939 27.072  20.092 1.00 12.11 ?  105  ASN A CB   1 
ATOM   1388  C CG   . ASN A 1 139 ? -14.014 28.015  19.309 1.00 13.18 ?  105  ASN A CG   1 
ATOM   1389  O OD1  . ASN A 1 139 ? -14.265 29.236  19.295 1.00 13.21 ?  105  ASN A OD1  1 
ATOM   1390  N ND2  . ASN A 1 139 ? -13.029 27.496  18.604 1.00 11.47 ?  105  ASN A ND2  1 
ATOM   1391  H H    . ASN A 1 139 ? -15.807 25.665  21.885 1.00 12.04 ?  105  ASN A H    1 
ATOM   1392  H HA   . ASN A 1 139 ? -13.956 25.253  19.958 1.00 12.71 ?  105  ASN A HA   1 
ATOM   1393  H HB2  . ASN A 1 139 ? -15.640 26.788  19.485 1.00 14.53 ?  105  ASN A HB2  1 
ATOM   1394  H HB3  . ASN A 1 139 ? -15.319 27.584  20.823 1.00 14.53 ?  105  ASN A HB3  1 
ATOM   1395  H HD21 . ASN A 1 139 ? -12.502 28.010  18.160 1.00 13.76 ?  105  ASN A HD21 1 
ATOM   1396  H HD22 . ASN A 1 139 ? -12.913 26.644  18.589 1.00 13.76 ?  105  ASN A HD22 1 
ATOM   1397  N N    . TRP A 1 140 ? -12.334 25.127  21.995 1.00 11.35 ?  106  TRP A N    1 
ATOM   1398  C CA   . TRP A 1 140 ? -11.105 25.293  22.753 1.00 11.20 ?  106  TRP A CA   1 
ATOM   1399  C C    . TRP A 1 140 ? -10.042 25.990  21.900 1.00 11.37 ?  106  TRP A C    1 
ATOM   1400  O O    . TRP A 1 140 ? -10.039 25.930  20.661 1.00 12.08 ?  106  TRP A O    1 
ATOM   1401  C CB   . TRP A 1 140 ? -10.598 23.914  23.209 1.00 11.06 ?  106  TRP A CB   1 
ATOM   1402  C CG   . TRP A 1 140 ? -11.398 23.275  24.302 1.00 10.27 ?  106  TRP A CG   1 
ATOM   1403  C CD1  . TRP A 1 140 ? -12.087 22.095  24.223 1.00 11.17 ?  106  TRP A CD1  1 
ATOM   1404  C CD2  . TRP A 1 140 ? -11.571 23.744  25.652 1.00 10.02 ?  106  TRP A CD2  1 
ATOM   1405  N NE1  . TRP A 1 140 ? -12.651 21.788  25.429 1.00 10.83 ?  106  TRP A NE1  1 
ATOM   1406  C CE2  . TRP A 1 140 ? -12.363 22.780  26.325 1.00 11.02 ?  106  TRP A CE2  1 
ATOM   1407  C CE3  . TRP A 1 140 ? -11.148 24.881  26.370 1.00 11.16 ?  106  TRP A CE3  1 
ATOM   1408  C CZ2  . TRP A 1 140 ? -12.758 22.933  27.635 1.00 11.72 ?  106  TRP A CZ2  1 
ATOM   1409  C CZ3  . TRP A 1 140 ? -11.531 25.017  27.690 1.00 12.16 ?  106  TRP A CZ3  1 
ATOM   1410  C CH2  . TRP A 1 140 ? -12.339 24.049  28.305 1.00 11.87 ?  106  TRP A CH2  1 
ATOM   1411  H H    . TRP A 1 140 ? -12.549 24.303  21.871 1.00 13.63 ?  106  TRP A H    1 
ATOM   1412  H HA   . TRP A 1 140 ? -11.264 25.842  23.537 1.00 13.44 ?  106  TRP A HA   1 
ATOM   1413  H HB2  . TRP A 1 140 ? -10.615 23.313  22.448 1.00 13.28 ?  106  TRP A HB2  1 
ATOM   1414  H HB3  . TRP A 1 140 ? -9.689  24.013  23.534 1.00 13.28 ?  106  TRP A HB3  1 
ATOM   1415  H HD1  . TRP A 1 140 ? -12.160 21.575  23.456 1.00 13.40 ?  106  TRP A HD1  1 
ATOM   1416  H HE1  . TRP A 1 140 ? -13.114 21.083  25.597 1.00 13.00 ?  106  TRP A HE1  1 
ATOM   1417  H HE3  . TRP A 1 140 ? -10.620 25.528  25.961 1.00 13.40 ?  106  TRP A HE3  1 
ATOM   1418  H HZ2  . TRP A 1 140 ? -13.294 22.296  28.052 1.00 14.06 ?  106  TRP A HZ2  1 
ATOM   1419  H HZ3  . TRP A 1 140 ? -11.250 25.758  28.176 1.00 14.59 ?  106  TRP A HZ3  1 
ATOM   1420  H HH2  . TRP A 1 140 ? -12.596 24.169  29.190 1.00 14.25 ?  106  TRP A HH2  1 
ATOM   1421  N N    . GLY A 1 141 ? -9.054  26.584  22.590 1.00 11.10 ?  107  GLY A N    1 
ATOM   1422  C CA   . GLY A 1 141 ? -8.018  27.327  21.917 1.00 13.38 ?  107  GLY A CA   1 
ATOM   1423  C C    . GLY A 1 141 ? -6.932  26.465  21.295 1.00 13.24 ?  107  GLY A C    1 
ATOM   1424  O O    . GLY A 1 141 ? -6.876  25.253  21.474 1.00 12.73 ?  107  GLY A O    1 
ATOM   1425  H H    . GLY A 1 141 ? -8.974  26.562  23.446 1.00 13.32 ?  107  GLY A H    1 
ATOM   1426  H HA2  . GLY A 1 141 ? -8.421  27.855  21.210 1.00 16.06 ?  107  GLY A HA2  1 
ATOM   1427  H HA3  . GLY A 1 141 ? -7.596  27.923  22.555 1.00 16.06 ?  107  GLY A HA3  1 
ATOM   1428  N N    . ASN A 1 142 ? -6.042  27.125  20.563 1.00 10.82 ?  108  ASN A N    1 
ATOM   1429  C CA   . ASN A 1 142 ? -4.779  26.658  19.998 1.00 11.34 ?  108  ASN A CA   1 
ATOM   1430  C C    . ASN A 1 142 ? -4.899  25.886  18.699 1.00 12.18 ?  108  ASN A C    1 
ATOM   1431  O O    . ASN A 1 142 ? -3.888  25.327  18.225 1.00 11.96 ?  108  ASN A O    1 
ATOM   1432  C CB   . ASN A 1 142 ? -3.896  25.923  21.018 1.00 13.07 ?  108  ASN A CB   1 
ATOM   1433  C CG   . ASN A 1 142 ? -3.388  26.851  22.084 1.00 13.76 ?  108  ASN A CG   1 
ATOM   1434  O OD1  . ASN A 1 142 ? -3.068  28.002  21.770 1.00 15.42 ?  108  ASN A OD1  1 
ATOM   1435  N ND2  . ASN A 1 142 ? -3.386  26.401  23.305 1.00 13.72 ?  108  ASN A ND2  1 
ATOM   1436  H H    . ASN A 1 142 ? -6.164  27.950  20.355 1.00 12.98 ?  108  ASN A H    1 
ATOM   1437  H HA   . ASN A 1 142 ? -4.289  27.454  19.737 1.00 13.61 ?  108  ASN A HA   1 
ATOM   1438  H HB2  . ASN A 1 142 ? -4.415  25.224  21.446 1.00 15.69 ?  108  ASN A HB2  1 
ATOM   1439  H HB3  . ASN A 1 142 ? -3.132  25.537  20.561 1.00 15.69 ?  108  ASN A HB3  1 
ATOM   1440  H HD21 . ASN A 1 142 ? -3.103  26.899  23.946 1.00 16.46 ?  108  ASN A HD21 1 
ATOM   1441  H HD22 . ASN A 1 142 ? -3.667  25.605  23.470 1.00 16.46 ?  108  ASN A HD22 1 
ATOM   1442  N N    . TYR A 1 143 ? -6.079  25.885  18.056 1.00 11.19 ?  109  TYR A N    1 
ATOM   1443  C CA   . TYR A 1 143 ? -6.214  25.393  16.692 1.00 11.78 ?  109  TYR A CA   1 
ATOM   1444  C C    . TYR A 1 143 ? -6.120  26.595  15.761 1.00 12.29 ?  109  TYR A C    1 
ATOM   1445  O O    . TYR A 1 143 ? -7.015  27.451  15.738 1.00 13.52 ?  109  TYR A O    1 
ATOM   1446  C CB   . TYR A 1 143 ? -7.545  24.681  16.482 1.00 11.63 ?  109  TYR A CB   1 
ATOM   1447  C CG   . TYR A 1 143 ? -7.755  23.424  17.301 1.00 11.08 ?  109  TYR A CG   1 
ATOM   1448  C CD1  . TYR A 1 143 ? -7.232  22.211  16.878 1.00 11.60 ?  109  TYR A CD1  1 
ATOM   1449  C CD2  . TYR A 1 143 ? -8.473  23.434  18.471 1.00 11.15 ?  109  TYR A CD2  1 
ATOM   1450  C CE1  . TYR A 1 143 ? -7.418  21.057  17.598 1.00 10.03 ?  109  TYR A CE1  1 
ATOM   1451  C CE2  . TYR A 1 143 ? -8.664  22.321  19.219 1.00 11.14 ?  109  TYR A CE2  1 
ATOM   1452  C CZ   . TYR A 1 143 ? -8.147  21.102  18.768 1.00 10.41 ?  109  TYR A CZ   1 
ATOM   1453  O OH   . TYR A 1 143 ? -8.374  19.972  19.537 1.00 11.13 ?  109  TYR A OH   1 
ATOM   1454  H H    . TYR A 1 143 ? -6.815  26.168  18.399 1.00 13.43 ?  109  TYR A H    1 
ATOM   1455  H HA   . TYR A 1 143 ? -5.498  24.765  16.508 1.00 14.13 ?  109  TYR A HA   1 
ATOM   1456  H HB2  . TYR A 1 143 ? -8.259  25.296  16.713 1.00 13.95 ?  109  TYR A HB2  1 
ATOM   1457  H HB3  . TYR A 1 143 ? -7.612  24.431  15.548 1.00 13.95 ?  109  TYR A HB3  1 
ATOM   1458  H HD1  . TYR A 1 143 ? -6.743  22.179  16.088 1.00 13.92 ?  109  TYR A HD1  1 
ATOM   1459  H HD2  . TYR A 1 143 ? -8.843  24.237  18.761 1.00 13.38 ?  109  TYR A HD2  1 
ATOM   1460  H HE1  . TYR A 1 143 ? -7.057  20.254  17.299 1.00 12.03 ?  109  TYR A HE1  1 
ATOM   1461  H HE2  . TYR A 1 143 ? -9.132  22.366  20.021 1.00 13.37 ?  109  TYR A HE2  1 
ATOM   1462  H HH   . TYR A 1 143 ? -8.088  19.291  19.137 1.00 13.36 ?  109  TYR A HH   1 
ATOM   1463  N N    . LYS A 1 144 ? -5.045  26.668  14.969 1.00 12.07 ?  110  LYS A N    1 
ATOM   1464  C CA   . LYS A 1 144 ? -4.890  27.814  14.103 1.00 11.65 ?  110  LYS A CA   1 
ATOM   1465  C C    . LYS A 1 144 ? -6.036  27.921  13.094 1.00 12.93 ?  110  LYS A C    1 
ATOM   1466  O O    . LYS A 1 144 ? -6.512  29.030  12.800 1.00 13.53 ?  110  LYS A O    1 
ATOM   1467  C CB   . LYS A 1 144 ? -3.549  27.815  13.384 1.00 14.51 ?  110  LYS A CB   1 
ATOM   1468  C CG   . LYS A 1 144 ? -3.365  26.738  12.382 1.00 16.93 ?  110  LYS A CG   1 
ATOM   1469  C CD   . LYS A 1 144 ? -1.976  26.827  11.719 1.00 20.76 ?  110  LYS A CD   1 
ATOM   1470  C CE   . LYS A 1 144 ? -1.748  25.713  10.814 1.00 22.22 ?  110  LYS A CE   1 
ATOM   1471  N NZ   . LYS A 1 144 ? -2.747  25.727  9.699  1.00 30.11 ?  110  LYS A NZ   1 
ATOM   1472  H H    . LYS A 1 144 ? -4.417  26.082  14.923 1.00 14.49 ?  110  LYS A H    1 
ATOM   1473  H HA   . LYS A 1 144 ? -4.905  28.601  14.671 1.00 13.99 ?  110  LYS A HA   1 
ATOM   1474  H HB2  . LYS A 1 144 ? -3.451  28.661  12.921 1.00 17.41 ?  110  LYS A HB2  1 
ATOM   1475  H HB3  . LYS A 1 144 ? -2.847  27.717  14.047 1.00 17.41 ?  110  LYS A HB3  1 
ATOM   1476  H HG2  . LYS A 1 144 ? -3.441  25.875  12.819 1.00 20.31 ?  110  LYS A HG2  1 
ATOM   1477  H HG3  . LYS A 1 144 ? -4.040  26.821  11.691 1.00 20.31 ?  110  LYS A HG3  1 
ATOM   1478  H HD2  . LYS A 1 144 ? -1.915  27.651  11.211 1.00 24.91 ?  110  LYS A HD2  1 
ATOM   1479  H HD3  . LYS A 1 144 ? -1.290  26.808  12.405 1.00 24.91 ?  110  LYS A HD3  1 
ATOM   1480  H HE2  . LYS A 1 144 ? -0.859  25.782  10.432 1.00 26.67 ?  110  LYS A HE2  1 
ATOM   1481  H HE3  . LYS A 1 144 ? -1.838  24.878  11.299 1.00 26.67 ?  110  LYS A HE3  1 
ATOM   1482  H HZ1  . LYS A 1 144 ? -2.596  25.046  9.147  1.00 36.13 ?  110  LYS A HZ1  1 
ATOM   1483  H HZ2  . LYS A 1 144 ? -3.571  25.655  10.028 1.00 36.13 ?  110  LYS A HZ2  1 
ATOM   1484  H HZ3  . LYS A 1 144 ? -2.684  26.488  9.243  1.00 36.13 ?  110  LYS A HZ3  1 
ATOM   1485  N N    . ASN A 1 145 ? -6.509  26.793  12.576 1.00 12.63 ?  111  ASN A N    1 
ATOM   1486  C CA   . ASN A 1 145 ? -7.561  26.838  11.567 1.00 12.17 ?  111  ASN A CA   1 
ATOM   1487  C C    . ASN A 1 145 ? -8.887  27.230  12.198 1.00 12.63 ?  111  ASN A C    1 
ATOM   1488  O O    . ASN A 1 145 ? -9.690  27.945  11.578 1.00 13.20 ?  111  ASN A O    1 
ATOM   1489  C CB   . ASN A 1 145 ? -7.653  25.526  10.810 1.00 12.95 ?  111  ASN A CB   1 
ATOM   1490  C CG   . ASN A 1 145 ? -6.394  25.239  10.020 1.00 15.77 ?  111  ASN A CG   1 
ATOM   1491  O OD1  . ASN A 1 145 ? -5.643  26.159  9.692  1.00 17.88 ?  111  ASN A OD1  1 
ATOM   1492  N ND2  . ASN A 1 145 ? -6.163  23.981  9.712  1.00 15.01 ?  111  ASN A ND2  1 
ATOM   1493  H H    . ASN A 1 145 ? -6.244  26.003  12.786 1.00 15.15 ?  111  ASN A H    1 
ATOM   1494  H HA   . ASN A 1 145 ? -7.338  27.510  10.905 1.00 14.61 ?  111  ASN A HA   1 
ATOM   1495  H HB2  . ASN A 1 145 ? -7.786  24.802  11.442 1.00 15.55 ?  111  ASN A HB2  1 
ATOM   1496  H HB3  . ASN A 1 145 ? -8.398  25.567  10.190 1.00 15.55 ?  111  ASN A HB3  1 
ATOM   1497  H HD21 . ASN A 1 145 ? -5.461  23.769  9.264  1.00 18.01 ?  111  ASN A HD21 1 
ATOM   1498  H HD22 . ASN A 1 145 ? -6.716  23.370  9.960  1.00 18.01 ?  111  ASN A HD22 1 
ATOM   1499  N N    . ASP A 1 146 ? -9.151  26.794  13.429 1.00 11.83 ?  112  ASP A N    1 
ATOM   1500  C CA   . ASP A 1 146 ? -10.372 27.203  14.102 1.00 12.17 ?  112  ASP A CA   1 
ATOM   1501  C C    . ASP A 1 146 ? -10.366 28.694  14.392 1.00 12.24 ?  112  ASP A C    1 
ATOM   1502  O O    . ASP A 1 146 ? -11.379 29.371  14.209 1.00 12.94 ?  112  ASP A O    1 
ATOM   1503  C CB   . ASP A 1 146 ? -10.602 26.435  15.413 1.00 11.17 ?  112  ASP A CB   1 
ATOM   1504  C CG   . ASP A 1 146 ? -10.783 24.939  15.232 1.00 11.43 ?  112  ASP A CG   1 
ATOM   1505  O OD1  . ASP A 1 146 ? -10.688 24.396  14.107 1.00 11.60 ?  112  ASP A OD1  1 
ATOM   1506  O OD2  . ASP A 1 146 ? -11.003 24.272  16.258 1.00 11.28 ?  112  ASP A OD2  1 
ATOM   1507  H H    . ASP A 1 146 ? -8.646  26.269  13.886 1.00 14.20 ?  112  ASP A H    1 
ATOM   1508  H HA   . ASP A 1 146 ? -11.106 26.985  13.507 1.00 14.61 ?  112  ASP A HA   1 
ATOM   1509  H HB2  . ASP A 1 146 ? -9.835  26.570  15.991 1.00 13.40 ?  112  ASP A HB2  1 
ATOM   1510  H HB3  . ASP A 1 146 ? -11.402 26.780  15.838 1.00 13.40 ?  112  ASP A HB3  1 
ATOM   1511  N N    . ASP A 1 147 ? -9.247  29.215  14.863 1.00 12.41 ?  113  ASP A N    1 
ATOM   1512  C CA   . ASP A 1 147 ? -9.155  30.642  15.151 1.00 12.38 ?  113  ASP A CA   1 
ATOM   1513  C C    . ASP A 1 147 ? -9.471  31.458  13.899 1.00 14.98 ?  113  ASP A C    1 
ATOM   1514  O O    . ASP A 1 147 ? -10.214 32.439  13.967 1.00 13.48 ?  113  ASP A O    1 
ATOM   1515  C CB   . ASP A 1 147 ? -7.770  31.014  15.688 1.00 13.57 ?  113  ASP A CB   1 
ATOM   1516  C CG   . ASP A 1 147 ? -7.517  30.446  17.049 1.00 14.60 ?  113  ASP A CG   1 
ATOM   1517  O OD1  . ASP A 1 147 ? -8.418  29.871  17.684 1.00 13.79 ?  113  ASP A OD1  1 
ATOM   1518  O OD2  . ASP A 1 147 ? -6.330  30.638  17.481 1.00 17.57 ?  113  ASP A OD2  1 
ATOM   1519  H H    . ASP A 1 147 ? -8.528  28.772  15.025 1.00 14.90 ?  113  ASP A H    1 
ATOM   1520  H HA   . ASP A 1 147 ? -9.797  30.857  15.845 1.00 14.85 ?  113  ASP A HA   1 
ATOM   1521  H HB2  . ASP A 1 147 ? -7.093  30.669  15.087 1.00 16.29 ?  113  ASP A HB2  1 
ATOM   1522  H HB3  . ASP A 1 147 ? -7.701  31.980  15.747 1.00 16.29 ?  113  ASP A HB3  1 
ATOM   1523  N N    . GLU A 1 148 ? -8.937  31.048  12.747 1.00 12.66 ?  114  GLU A N    1 
ATOM   1524  C CA   . GLU A 1 148 ? -9.187  31.761  11.486 1.00 13.11 ?  114  GLU A CA   1 
ATOM   1525  C C    . GLU A 1 148 ? -10.658 31.629  11.100 1.00 12.86 ?  114  GLU A C    1 
ATOM   1526  O O    . GLU A 1 148 ? -11.302 32.609  10.694 1.00 14.07 ?  114  GLU A O    1 
ATOM   1527  C CB   . GLU A 1 148 ? -8.295  31.185  10.387 1.00 15.47 ?  114  GLU A CB   1 
ATOM   1528  C CG   . GLU A 1 148 ? -8.369  31.882  9.015  1.00 19.44 ?  114  GLU A CG   1 
ATOM   1529  C CD   . GLU A 1 148 ? -8.021  33.368  8.995  1.00 28.27 ?  114  GLU A CD   1 
ATOM   1530  O OE1  . GLU A 1 148 ? -7.544  33.928  10.007 1.00 33.40 ?  114  GLU A OE1  1 
ATOM   1531  O OE2  . GLU A 1 148 ? -8.213  33.988  7.914  1.00 42.59 ?  114  GLU A OE2  1 
ATOM   1532  H H    . GLU A 1 148 ? -8.427  30.361  12.665 1.00 15.20 ?  114  GLU A H    1 
ATOM   1533  H HA   . GLU A 1 148 ? -8.971  32.701  11.588 1.00 15.73 ?  114  GLU A HA   1 
ATOM   1534  H HB2  . GLU A 1 148 ? -7.374  31.239  10.686 1.00 18.57 ?  114  GLU A HB2  1 
ATOM   1535  H HB3  . GLU A 1 148 ? -8.546  30.258  10.250 1.00 18.57 ?  114  GLU A HB3  1 
ATOM   1536  H HG2  . GLU A 1 148 ? -7.750  31.437  8.415  1.00 23.32 ?  114  GLU A HG2  1 
ATOM   1537  H HG3  . GLU A 1 148 ? -9.275  31.797  8.680  1.00 23.32 ?  114  GLU A HG3  1 
ATOM   1538  N N    . PHE A 1 149 ? -11.198 30.421  11.171 1.00 13.21 ?  115  PHE A N    1 
ATOM   1539  C CA   . PHE A 1 149 ? -12.601 30.173  10.836 1.00 12.10 ?  115  PHE A CA   1 
ATOM   1540  C C    . PHE A 1 149 ? -13.541 31.025  11.668 1.00 13.41 ?  115  PHE A C    1 
ATOM   1541  O O    . PHE A 1 149 ? -14.480 31.644  11.127 1.00 13.18 ?  115  PHE A O    1 
ATOM   1542  C CB   . PHE A 1 149 ? -12.886 28.682  11.029 1.00 13.35 ?  115  PHE A CB   1 
ATOM   1543  C CG   . PHE A 1 149 ? -14.310 28.276  10.818 1.00 12.09 ?  115  PHE A CG   1 
ATOM   1544  C CD1  . PHE A 1 149 ? -14.865 28.339  9.541  1.00 13.46 ?  115  PHE A CD1  1 
ATOM   1545  C CD2  . PHE A 1 149 ? -15.061 27.833  11.869 1.00 13.04 ?  115  PHE A CD2  1 
ATOM   1546  C CE1  . PHE A 1 149 ? -16.192 27.927  9.352  1.00 14.58 ?  115  PHE A CE1  1 
ATOM   1547  C CE2  . PHE A 1 149 ? -16.383 27.397  11.665 1.00 14.63 ?  115  PHE A CE2  1 
ATOM   1548  C CZ   . PHE A 1 149 ? -16.925 27.476  10.419 1.00 13.69 ?  115  PHE A CZ   1 
ATOM   1549  H H    . PHE A 1 149 ? -10.772 29.714  11.412 1.00 15.85 ?  115  PHE A H    1 
ATOM   1550  H HA   . PHE A 1 149 ? -12.761 30.410  9.909  1.00 14.52 ?  115  PHE A HA   1 
ATOM   1551  H HB2  . PHE A 1 149 ? -12.345 28.182  10.398 1.00 16.02 ?  115  PHE A HB2  1 
ATOM   1552  H HB3  . PHE A 1 149 ? -12.647 28.439  11.937 1.00 16.02 ?  115  PHE A HB3  1 
ATOM   1553  H HD1  . PHE A 1 149 ? -14.361 28.649  8.824  1.00 16.15 ?  115  PHE A HD1  1 
ATOM   1554  H HD2  . PHE A 1 149 ? -14.697 27.820  12.725 1.00 15.65 ?  115  PHE A HD2  1 
ATOM   1555  H HE1  . PHE A 1 149 ? -16.574 27.961  8.505  1.00 17.50 ?  115  PHE A HE1  1 
ATOM   1556  H HE2  . PHE A 1 149 ? -16.881 27.058  12.373 1.00 17.56 ?  115  PHE A HE2  1 
ATOM   1557  H HZ   . PHE A 1 149 ? -17.809 27.219  10.289 1.00 16.42 ?  115  PHE A HZ   1 
ATOM   1558  N N    . ILE A 1 150 ? -13.341 31.086  12.979 1.00 13.02 ?  116  ILE A N    1 
ATOM   1559  C CA   . ILE A 1 150 ? -14.230 31.848  13.844 1.00 13.30 ?  116  ILE A CA   1 
ATOM   1560  C C    . ILE A 1 150 ? -14.035 33.347  13.641 1.00 14.06 ?  116  ILE A C    1 
ATOM   1561  O O    . ILE A 1 150 ? -14.997 34.123  13.693 1.00 15.55 ?  116  ILE A O    1 
ATOM   1562  C CB   . ILE A 1 150 ? -14.014 31.429  15.314 1.00 12.59 ?  116  ILE A CB   1 
ATOM   1563  C CG1  . ILE A 1 150 ? -14.386 29.968  15.528 1.00 13.59 ?  116  ILE A CG1  1 
ATOM   1564  C CG2  . ILE A 1 150 ? -14.759 32.401  16.245 1.00 14.89 ?  116  ILE A CG2  1 
ATOM   1565  C CD1  . ILE A 1 150 ? -15.787 29.597  15.086 1.00 13.99 ?  116  ILE A CD1  1 
ATOM   1566  H H    . ILE A 1 150 ? -12.698 30.693  13.394 1.00 15.63 ?  116  ILE A H    1 
ATOM   1567  H HA   . ILE A 1 150 ? -15.147 31.646  13.602 1.00 15.96 ?  116  ILE A HA   1 
ATOM   1568  H HB   . ILE A 1 150 ? -13.071 31.491  15.534 1.00 15.11 ?  116  ILE A HB   1 
ATOM   1569  H HG12 . ILE A 1 150 ? -13.766 29.416  15.027 1.00 16.30 ?  116  ILE A HG12 1 
ATOM   1570  H HG13 . ILE A 1 150 ? -14.316 29.769  16.475 1.00 16.30 ?  116  ILE A HG13 1 
ATOM   1571  H HG21 . ILE A 1 150 ? -14.728 32.056  17.151 1.00 17.86 ?  116  ILE A HG21 1 
ATOM   1572  H HG22 . ILE A 1 150 ? -14.327 33.269  16.207 1.00 17.86 ?  116  ILE A HG22 1 
ATOM   1573  H HG23 . ILE A 1 150 ? -15.680 32.477  15.951 1.00 17.86 ?  116  ILE A HG23 1 
ATOM   1574  H HD11 . ILE A 1 150 ? -15.973 28.685  15.359 1.00 16.79 ?  116  ILE A HD11 1 
ATOM   1575  H HD12 . ILE A 1 150 ? -16.421 30.203  15.502 1.00 16.79 ?  116  ILE A HD12 1 
ATOM   1576  H HD13 . ILE A 1 150 ? -15.844 29.671  14.121 1.00 16.79 ?  116  ILE A HD13 1 
ATOM   1577  N N    . SER A 1 151 ? -12.794 33.784  13.416 1.00 13.54 ?  117  SER A N    1 
ATOM   1578  C CA   . SER A 1 151 ? -12.547 35.199  13.154 1.00 14.87 ?  117  SER A CA   1 
ATOM   1579  C C    . SER A 1 151 ? -13.278 35.645  11.905 1.00 16.38 ?  117  SER A C    1 
ATOM   1580  O O    . SER A 1 151 ? -13.888 36.733  11.885 1.00 18.09 ?  117  SER A O    1 
ATOM   1581  C CB   . SER A 1 151 ? -11.053 35.424  13.005 1.00 15.51 ?  117  SER A CB   1 
ATOM   1582  O OG   . SER A 1 151 ? -10.790 36.774  12.621 1.00 23.25 ?  117  SER A OG   1 
ATOM   1583  H H    . SER A 1 151 ? -12.091 33.290  13.409 1.00 16.25 ?  117  SER A H    1 
ATOM   1584  H HA   . SER A 1 151 ? -12.866 35.732  13.899 1.00 17.84 ?  117  SER A HA   1 
ATOM   1585  H HB2  . SER A 1 151 ? -10.618 35.245  13.853 1.00 18.61 ?  117  SER A HB2  1 
ATOM   1586  H HB3  . SER A 1 151 ? -10.708 34.827  12.322 1.00 18.61 ?  117  SER A HB3  1 
ATOM   1587  H HG   . SER A 1 151 ? -9.962  36.894  12.542 1.00 27.90 ?  117  SER A HG   1 
ATOM   1588  N N    . LYS A 1 152 ? -13.220 34.837  10.851 1.00 15.79 ?  118  LYS A N    1 
ATOM   1589  C CA   . LYS A 1 152 ? -13.830 35.179  9.579  1.00 16.08 ?  118  LYS A CA   1 
ATOM   1590  C C    . LYS A 1 152 ? -15.325 34.959  9.604  1.00 16.47 ?  118  LYS A C    1 
ATOM   1591  O O    . LYS A 1 152 ? -16.040 35.606  8.815  1.00 19.08 ?  118  LYS A O    1 
ATOM   1592  C CB   . LYS A 1 152 ? -13.159 34.391  8.466  1.00 18.54 ?  118  LYS A CB   1 
ATOM   1593  C CG   . LYS A 1 152 ? -11.715 34.855  8.135  1.00 27.11 ?  118  LYS A CG   1 
ATOM   1594  C CD   . LYS A 1 152 ? -11.645 36.390  8.126  1.00 42.55 ?  118  LYS A CD   1 
ATOM   1595  C CE   . LYS A 1 152 ? -10.566 36.943  7.211  1.00 51.02 ?  118  LYS A CE   1 
ATOM   1596  N NZ   . LYS A 1 152 ? -9.267  36.254  7.397  1.00 48.48 ?  118  LYS A NZ   1 
ATOM   1597  H H    . LYS A 1 152 ? -12.825 34.073  10.849 1.00 18.94 ?  118  LYS A H    1 
ATOM   1598  H HA   . LYS A 1 152 ? -13.688 36.116  9.372  1.00 19.30 ?  118  LYS A HA   1 
ATOM   1599  H HB2  . LYS A 1 152 ? -13.115 33.459  8.730  1.00 22.25 ?  118  LYS A HB2  1 
ATOM   1600  H HB3  . LYS A 1 152 ? -13.690 34.483  7.659  1.00 22.25 ?  118  LYS A HB3  1 
ATOM   1601  H HG2  . LYS A 1 152 ? -11.101 34.520  8.808  1.00 32.53 ?  118  LYS A HG2  1 
ATOM   1602  H HG3  . LYS A 1 152 ? -11.458 34.527  7.259  1.00 32.53 ?  118  LYS A HG3  1 
ATOM   1603  H HD2  . LYS A 1 152 ? -12.497 36.741  7.824  1.00 51.06 ?  118  LYS A HD2  1 
ATOM   1604  H HD3  . LYS A 1 152 ? -11.458 36.701  9.026  1.00 51.06 ?  118  LYS A HD3  1 
ATOM   1605  H HE2  . LYS A 1 152 ? -10.840 36.826  6.288  1.00 61.22 ?  118  LYS A HE2  1 
ATOM   1606  H HE3  . LYS A 1 152 ? -10.438 37.885  7.402  1.00 61.22 ?  118  LYS A HE3  1 
ATOM   1607  H HZ1  . LYS A 1 152 ? -8.656  36.606  6.855  1.00 58.17 ?  118  LYS A HZ1  1 
ATOM   1608  H HZ2  . LYS A 1 152 ? -8.993  36.345  8.239  1.00 58.17 ?  118  LYS A HZ2  1 
ATOM   1609  H HZ3  . LYS A 1 152 ? -9.353  35.388  7.213  1.00 58.17 ?  118  LYS A HZ3  1 
ATOM   1610  N N    . ASN A 1 153 ? -15.848 34.141  10.512 1.00 15.48 ?  119  ASN A N    1 
ATOM   1611  C CA   . ASN A 1 153 ? -17.251 33.716  10.471 1.00 15.64 ?  119  ASN A CA   1 
ATOM   1612  C C    . ASN A 1 153 ? -17.819 33.715  11.878 1.00 13.24 ?  119  ASN A C    1 
ATOM   1613  O O    . ASN A 1 153 ? -18.075 32.661  12.465 1.00 15.44 ?  119  ASN A O    1 
ATOM   1614  C CB   . ASN A 1 153 ? -17.377 32.339  9.825  1.00 14.37 ?  119  ASN A CB   1 
ATOM   1615  C CG   . ASN A 1 153 ? -16.740 32.277  8.460  1.00 18.04 ?  119  ASN A CG   1 
ATOM   1616  O OD1  . ASN A 1 153 ? -17.293 32.785  7.464  1.00 21.31 ?  119  ASN A OD1  1 
ATOM   1617  N ND2  . ASN A 1 153 ? -15.573 31.696  8.366  1.00 18.02 ?  119  ASN A ND2  1 
ATOM   1618  H H    . ASN A 1 153 ? -15.407 33.812  11.173 1.00 18.57 ?  119  ASN A H    1 
ATOM   1619  H HA   . ASN A 1 153 ? -17.757 34.354  9.945  1.00 18.77 ?  119  ASN A HA   1 
ATOM   1620  H HB2  . ASN A 1 153 ? -16.939 31.683  10.390 1.00 17.25 ?  119  ASN A HB2  1 
ATOM   1621  H HB3  . ASN A 1 153 ? -18.317 32.120  9.729  1.00 17.25 ?  119  ASN A HB3  1 
ATOM   1622  H HD21 . ASN A 1 153 ? -15.180 31.642  7.603  1.00 21.62 ?  119  ASN A HD21 1 
ATOM   1623  H HD22 . ASN A 1 153 ? -15.199 31.368  9.067  1.00 21.62 ?  119  ASN A HD22 1 
ATOM   1624  N N    . PRO A 1 154 ? -18.035 34.893  12.465 1.00 13.64 ?  120  PRO A N    1 
ATOM   1625  C CA   . PRO A 1 154 ? -18.535 34.924  13.843 1.00 14.95 ?  120  PRO A CA   1 
ATOM   1626  C C    . PRO A 1 154 ? -19.888 34.244  14.023 1.00 14.76 ?  120  PRO A C    1 
ATOM   1627  O O    . PRO A 1 154 ? -20.256 33.853  15.140 1.00 14.57 ?  120  PRO A O    1 
ATOM   1628  C CB   . PRO A 1 154 ? -18.564 36.426  14.192 1.00 16.68 ?  120  PRO A CB   1 
ATOM   1629  C CG   . PRO A 1 154 ? -18.568 37.107  12.850 1.00 20.30 ?  120  PRO A CG   1 
ATOM   1630  C CD   . PRO A 1 154 ? -17.765 36.236  11.932 1.00 16.19 ?  120  PRO A CD   1 
ATOM   1631  H HA   . PRO A 1 154 ? -17.899 34.495  14.437 1.00 17.94 ?  120  PRO A HA   1 
ATOM   1632  H HB2  . PRO A 1 154 ? -19.366 36.638  14.696 1.00 20.02 ?  120  PRO A HB2  1 
ATOM   1633  H HB3  . PRO A 1 154 ? -17.777 36.666  14.706 1.00 20.02 ?  120  PRO A HB3  1 
ATOM   1634  H HG2  . PRO A 1 154 ? -19.480 37.190  12.530 1.00 24.36 ?  120  PRO A HG2  1 
ATOM   1635  H HG3  . PRO A 1 154 ? -18.163 37.985  12.929 1.00 24.36 ?  120  PRO A HG3  1 
ATOM   1636  H HD2  . PRO A 1 154 ? -18.072 36.316  11.015 1.00 19.42 ?  120  PRO A HD2  1 
ATOM   1637  H HD3  . PRO A 1 154 ? -16.820 36.450  11.985 1.00 19.42 ?  120  PRO A HD3  1 
ATOM   1638  N N    . SER A 1 155 ? -20.659 34.094  12.937 1.00 13.84 ?  121  SER A N    1 
ATOM   1639  C CA   . SER A 1 155 ? -21.947 33.397  13.015 1.00 14.96 ?  121  SER A CA   1 
ATOM   1640  C C    . SER A 1 155 ? -21.795 31.903  13.283 1.00 13.75 ?  121  SER A C    1 
ATOM   1641  O O    . SER A 1 155 ? -22.793 31.216  13.522 1.00 13.83 ?  121  SER A O    1 
ATOM   1642  C CB   . SER A 1 155 ? -22.752 33.616  11.718 1.00 15.97 ?  121  SER A CB   1 
ATOM   1643  O OG   . SER A 1 155 ? -22.148 32.988  10.596 1.00 15.44 ?  121  SER A OG   1 
ATOM   1644  H H    . SER A 1 155 ? -20.460 34.385  12.153 1.00 16.61 ?  121  SER A H    1 
ATOM   1645  H HA   . SER A 1 155 ? -22.458 33.777  13.747 1.00 17.95 ?  121  SER A HA   1 
ATOM   1646  H HB2  . SER A 1 155 ? -23.641 33.246  11.838 1.00 19.17 ?  121  SER A HB2  1 
ATOM   1647  H HB3  . SER A 1 155 ? -22.809 34.569  11.546 1.00 19.17 ?  121  SER A HB3  1 
ATOM   1648  H HG   . SER A 1 155 ? -21.533 33.472  10.293 1.00 18.53 ?  121  SER A HG   1 
ATOM   1649  N N    . ALA A 1 156 ? -20.560 31.389  13.296 1.00 13.21 ?  122  ALA A N    1 
ATOM   1650  C CA   . ALA A 1 156 ? -20.348 29.980  13.587 1.00 12.29 ?  122  ALA A CA   1 
ATOM   1651  C C    . ALA A 1 156 ? -20.535 29.633  15.065 1.00 12.21 ?  122  ALA A C    1 
ATOM   1652  O O    . ALA A 1 156 ? -20.615 28.437  15.389 1.00 13.75 ?  122  ALA A O    1 
ATOM   1653  C CB   . ALA A 1 156 ? -18.939 29.585  13.186 1.00 12.73 ?  122  ALA A CB   1 
ATOM   1654  H H    . ALA A 1 156 ? -19.842 31.836  13.140 1.00 15.85 ?  122  ALA A H    1 
ATOM   1655  H HA   . ALA A 1 156 ? -20.989 29.469  13.069 1.00 14.75 ?  122  ALA A HA   1 
ATOM   1656  H HB1  . ALA A 1 156 ? -18.779 28.667  13.458 1.00 15.27 ?  122  ALA A HB1  1 
ATOM   1657  H HB2  . ALA A 1 156 ? -18.850 29.664  12.223 1.00 15.27 ?  122  ALA A HB2  1 
ATOM   1658  H HB3  . ALA A 1 156 ? -18.308 30.175  13.626 1.00 15.27 ?  122  ALA A HB3  1 
ATOM   1659  N N    . LEU A 1 157 ? -20.599 30.607  15.966 1.00 11.24 ?  123  LEU A N    1 
ATOM   1660  C CA   . LEU A 1 157 ? -20.676 30.316  17.400 1.00 12.33 ?  123  LEU A CA   1 
ATOM   1661  C C    . LEU A 1 157 ? -22.106 30.295  17.912 1.00 13.47 ?  123  LEU A C    1 
ATOM   1662  O O    . LEU A 1 157 ? -23.001 30.988  17.401 1.00 14.03 ?  123  LEU A O    1 
ATOM   1663  C CB   . LEU A 1 157 ? -19.870 31.315  18.231 1.00 13.60 ?  123  LEU A CB   1 
ATOM   1664  C CG   . LEU A 1 157 ? -18.358 31.293  17.982 1.00 12.07 ?  123  LEU A CG   1 
ATOM   1665  C CD1  . LEU A 1 157 ? -17.709 32.379  18.857 1.00 14.19 ?  123  LEU A CD1  1 
ATOM   1666  C CD2  . LEU A 1 157 ? -17.741 29.906  18.229 1.00 13.63 ?  123  LEU A CD2  1 
ATOM   1667  H H    . LEU A 1 157 ? -20.599 31.445  15.775 1.00 13.48 ?  123  LEU A H    1 
ATOM   1668  H HA   . LEU A 1 157 ? -20.298 29.432  17.526 1.00 14.79 ?  123  LEU A HA   1 
ATOM   1669  H HB2  . LEU A 1 157 ? -20.187 32.209  18.027 1.00 16.32 ?  123  LEU A HB2  1 
ATOM   1670  H HB3  . LEU A 1 157 ? -20.014 31.119  19.170 1.00 16.32 ?  123  LEU A HB3  1 
ATOM   1671  H HG   . LEU A 1 157 ? -18.177 31.483  17.048 1.00 14.48 ?  123  LEU A HG   1 
ATOM   1672  H HD11 . LEU A 1 157 ? -16.747 32.346  18.739 1.00 17.03 ?  123  LEU A HD11 1 
ATOM   1673  H HD12 . LEU A 1 157 ? -18.046 33.247  18.585 1.00 17.03 ?  123  LEU A HD12 1 
ATOM   1674  H HD13 . LEU A 1 157 ? -17.935 32.212  19.786 1.00 17.03 ?  123  LEU A HD13 1 
ATOM   1675  H HD21 . LEU A 1 157 ? -16.775 29.975  18.172 1.00 16.35 ?  123  LEU A HD21 1 
ATOM   1676  H HD22 . LEU A 1 157 ? -17.999 29.598  19.112 1.00 16.35 ?  123  LEU A HD22 1 
ATOM   1677  H HD23 . LEU A 1 157 ? -18.069 29.290  17.555 1.00 16.35 ?  123  LEU A HD23 1 
ATOM   1678  N N    . LEU A 1 158 ? -22.325 29.508  18.945 1.00 11.66 ?  124  LEU A N    1 
ATOM   1679  C CA   . LEU A 1 158 ? -23.659 29.241  19.491 1.00 11.05 ?  124  LEU A CA   1 
ATOM   1680  C C    . LEU A 1 158 ? -24.172 30.375  20.370 1.00 13.85 ?  124  LEU A C    1 
ATOM   1681  O O    . LEU A 1 158 ? -23.483 30.858  21.263 1.00 13.65 ?  124  LEU A O    1 
ATOM   1682  C CB   . LEU A 1 158 ? -23.591 27.957  20.318 1.00 10.80 ?  124  LEU A CB   1 
ATOM   1683  C CG   . LEU A 1 158 ? -24.885 27.473  20.969 1.00 12.74 ?  124  LEU A CG   1 
ATOM   1684  C CD1  . LEU A 1 158 ? -25.929 27.153  19.921 1.00 12.96 ?  124  LEU A CD1  1 
ATOM   1685  C CD2  . LEU A 1 158 ? -24.624 26.298  21.902 1.00 13.16 ?  124  LEU A CD2  1 
ATOM   1686  H H    . LEU A 1 158 ? -21.701 29.097  19.370 1.00 13.99 ?  124  LEU A H    1 
ATOM   1687  H HA   . LEU A 1 158 ? -24.284 29.154  18.755 1.00 13.27 ?  124  LEU A HA   1 
ATOM   1688  H HB2  . LEU A 1 158 ? -23.286 27.244  19.736 1.00 12.96 ?  124  LEU A HB2  1 
ATOM   1689  H HB3  . LEU A 1 158 ? -22.952 28.098  21.034 1.00 12.96 ?  124  LEU A HB3  1 
ATOM   1690  H HG   . LEU A 1 158 ? -25.248 28.186  21.517 1.00 15.29 ?  124  LEU A HG   1 
ATOM   1691  H HD11 . LEU A 1 158 ? -26.703 26.762  20.355 1.00 15.56 ?  124  LEU A HD11 1 
ATOM   1692  H HD12 . LEU A 1 158 ? -26.183 27.973  19.468 1.00 15.56 ?  124  LEU A HD12 1 
ATOM   1693  H HD13 . LEU A 1 158 ? -25.554 26.526  19.283 1.00 15.56 ?  124  LEU A HD13 1 
ATOM   1694  H HD21 . LEU A 1 158 ? -25.459 26.033  22.318 1.00 15.80 ?  124  LEU A HD21 1 
ATOM   1695  H HD22 . LEU A 1 158 ? -24.262 25.560  21.388 1.00 15.80 ?  124  LEU A HD22 1 
ATOM   1696  H HD23 . LEU A 1 158 ? -23.987 26.570  22.582 1.00 15.80 ?  124  LEU A HD23 1 
ATOM   1697  N N    . LYS A 1 159 ? -25.421 30.768  20.130 1.00 13.98 ?  125  LYS A N    1 
ATOM   1698  C CA   . LYS A 1 159 ? -26.095 31.805  20.889 1.00 14.15 ?  125  LYS A CA   1 
ATOM   1699  C C    . LYS A 1 159 ? -27.384 31.290  21.488 1.00 14.01 ?  125  LYS A C    1 
ATOM   1700  O O    . LYS A 1 159 ? -27.994 30.326  21.008 1.00 15.86 ?  125  LYS A O    1 
ATOM   1701  C CB   . LYS A 1 159 ? -26.410 32.997  19.964 1.00 17.05 ?  125  LYS A CB   1 
ATOM   1702  C CG   . LYS A 1 159 ? -25.166 33.726  19.520 1.00 18.61 ?  125  LYS A CG   1 
ATOM   1703  C CD   . LYS A 1 159 ? -25.452 34.930  18.618 1.00 26.12 ?  125  LYS A CD   1 
ATOM   1704  C CE   . LYS A 1 159 ? -24.120 35.606  18.262 1.00 33.26 ?  125  LYS A CE   1 
ATOM   1705  N NZ   . LYS A 1 159 ? -24.128 36.262  16.920 1.00 46.10 ?  125  LYS A NZ   1 
ATOM   1706  H H    . LYS A 1 159 ? -25.912 30.433  19.508 1.00 16.78 ?  125  LYS A H    1 
ATOM   1707  H HA   . LYS A 1 159 ? -25.529 32.090  21.624 1.00 16.98 ?  125  LYS A HA   1 
ATOM   1708  H HB2  . LYS A 1 159 ? -26.868 32.671  19.173 1.00 20.46 ?  125  LYS A HB2  1 
ATOM   1709  H HB3  . LYS A 1 159 ? -26.976 33.625  20.439 1.00 20.46 ?  125  LYS A HB3  1 
ATOM   1710  H HG2  . LYS A 1 159 ? -24.696 34.049  20.304 1.00 22.33 ?  125  LYS A HG2  1 
ATOM   1711  H HG3  . LYS A 1 159 ? -24.603 33.112  19.024 1.00 22.33 ?  125  LYS A HG3  1 
ATOM   1712  H HD2  . LYS A 1 159 ? -25.886 34.637  17.802 1.00 31.35 ?  125  LYS A HD2  1 
ATOM   1713  H HD3  . LYS A 1 159 ? -26.016 35.567  19.084 1.00 31.35 ?  125  LYS A HD3  1 
ATOM   1714  H HE2  . LYS A 1 159 ? -23.927 36.287  18.925 1.00 39.91 ?  125  LYS A HE2  1 
ATOM   1715  H HE3  . LYS A 1 159 ? -23.419 34.936  18.261 1.00 39.91 ?  125  LYS A HE3  1 
ATOM   1716  H HZ1  . LYS A 1 159 ? -24.946 36.555  16.729 1.00 55.32 ?  125  LYS A HZ1  1 
ATOM   1717  H HZ2  . LYS A 1 159 ? -23.566 36.952  16.916 1.00 55.32 ?  125  LYS A HZ2  1 
ATOM   1718  H HZ3  . LYS A 1 159 ? -23.876 35.681  16.296 1.00 55.32 ?  125  LYS A HZ3  1 
ATOM   1719  N N    . ASN A 1 160 ? -27.794 31.933  22.593 1.00 16.45 ?  126  ASN A N    1 
ATOM   1720  C CA   . ASN A 1 160 ? -29.064 31.652  23.228 1.00 16.85 ?  126  ASN A CA   1 
ATOM   1721  C C    . ASN A 1 160 ? -30.193 32.348  22.471 1.00 17.91 ?  126  ASN A C    1 
ATOM   1722  O O    . ASN A 1 160 ? -29.994 32.987  21.432 1.00 18.36 ?  126  ASN A O    1 
ATOM   1723  C CB   . ASN A 1 160 ? -29.023 31.982  24.727 1.00 16.73 ?  126  ASN A CB   1 
ATOM   1724  C CG   . ASN A 1 160 ? -28.898 33.454  25.022 1.00 18.16 ?  126  ASN A CG   1 
ATOM   1725  O OD1  . ASN A 1 160 ? -29.147 34.320  24.174 1.00 18.47 ?  126  ASN A OD1  1 
ATOM   1726  N ND2  . ASN A 1 160 ? -28.505 33.756  26.252 1.00 21.29 ?  126  ASN A ND2  1 
ATOM   1727  H H    . ASN A 1 160 ? -27.338 32.544  22.991 1.00 19.74 ?  126  ASN A H    1 
ATOM   1728  H HA   . ASN A 1 160 ? -29.240 30.700  23.179 1.00 20.23 ?  126  ASN A HA   1 
ATOM   1729  H HB2  . ASN A 1 160 ? -29.843 31.666  25.139 1.00 20.07 ?  126  ASN A HB2  1 
ATOM   1730  H HB3  . ASN A 1 160 ? -28.260 31.535  25.125 1.00 20.07 ?  126  ASN A HB3  1 
ATOM   1731  H HD21 . ASN A 1 160 ? -28.414 34.578  26.485 1.00 25.55 ?  126  ASN A HD21 1 
ATOM   1732  H HD22 . ASN A 1 160 ? -28.341 33.128  26.817 1.00 25.55 ?  126  ASN A HD22 1 
ATOM   1733  N N    . GLN A 1 161 ? -31.405 32.210  23.013 1.00 18.83 ?  127  GLN A N    1 
ATOM   1734  C CA   . GLN A 1 161 ? -32.576 32.700  22.300 1.00 19.35 ?  127  GLN A CA   1 
ATOM   1735  C C    . GLN A 1 161 ? -32.635 34.218  22.336 1.00 23.09 ?  127  GLN A C    1 
ATOM   1736  O O    . GLN A 1 161 ? -33.373 34.814  21.530 1.00 25.87 ?  127  GLN A O    1 
ATOM   1737  C CB   . GLN A 1 161 ? -33.846 32.068  22.878 1.00 21.32 ?  127  GLN A CB   1 
ATOM   1738  C CG   . GLN A 1 161 ? -34.025 30.612  22.504 1.00 16.99 ?  127  GLN A CG   1 
ATOM   1739  C CD   . GLN A 1 161 ? -35.022 29.922  23.384 1.00 19.80 ?  127  GLN A CD   1 
ATOM   1740  O OE1  . GLN A 1 161 ? -34.729 29.532  24.517 1.00 20.00 ?  127  GLN A OE1  1 
ATOM   1741  N NE2  . GLN A 1 161 ? -36.255 29.783  22.878 1.00 22.64 ?  127  GLN A NE2  1 
ATOM   1742  H H    . GLN A 1 161 ? -31.569 31.844  23.774 1.00 22.60 ?  127  GLN A H    1 
ATOM   1743  H HA   . GLN A 1 161 ? -32.542 32.431  21.369 1.00 23.21 ?  127  GLN A HA   1 
ATOM   1744  H HB2  . GLN A 1 161 ? -33.810 32.124  23.845 1.00 25.59 ?  127  GLN A HB2  1 
ATOM   1745  H HB3  . GLN A 1 161 ? -34.616 32.556  22.546 1.00 25.59 ?  127  GLN A HB3  1 
ATOM   1746  H HG2  . GLN A 1 161 ? -34.339 30.554  21.588 1.00 20.38 ?  127  GLN A HG2  1 
ATOM   1747  H HG3  . GLN A 1 161 ? -33.175 30.153  22.593 1.00 20.38 ?  127  GLN A HG3  1 
ATOM   1748  H HE21 . GLN A 1 161 ? -36.433 30.083  22.091 1.00 27.16 ?  127  GLN A HE21 1 
ATOM   1749  H HE22 . GLN A 1 161 ? -36.868 29.395  23.339 1.00 27.16 ?  127  GLN A HE22 1 
ATOM   1750  N N    . ASN A 1 162 ? -31.867 34.858  23.215 1.00 18.80 ?  128  ASN A N    1 
ATOM   1751  C CA   . ASN A 1 162 ? -31.714 36.303  23.247 1.00 22.31 ?  128  ASN A CA   1 
ATOM   1752  C C    . ASN A 1 162 ? -30.520 36.779  22.446 1.00 19.73 ?  128  ASN A C    1 
ATOM   1753  O O    . ASN A 1 162 ? -30.062 37.910  22.641 1.00 24.18 ?  128  ASN A O    1 
ATOM   1754  C CB   . ASN A 1 162 ? -31.613 36.789  24.694 1.00 25.15 ?  128  ASN A CB   1 
ATOM   1755  C CG   . ASN A 1 162 ? -32.070 38.215  24.850 1.00 45.90 ?  128  ASN A CG   1 
ATOM   1756  O OD1  . ASN A 1 162 ? -32.864 38.711  24.048 1.00 43.56 ?  128  ASN A OD1  1 
ATOM   1757  N ND2  . ASN A 1 162 ? -31.558 38.894  25.867 1.00 55.76 ?  128  ASN A ND2  1 
ATOM   1758  H H    . ASN A 1 162 ? -31.410 34.459  23.824 1.00 22.56 ?  128  ASN A H    1 
ATOM   1759  H HA   . ASN A 1 162 ? -32.507 36.703  22.856 1.00 26.77 ?  128  ASN A HA   1 
ATOM   1760  H HB2  . ASN A 1 162 ? -32.171 36.230  25.257 1.00 30.18 ?  128  ASN A HB2  1 
ATOM   1761  H HB3  . ASN A 1 162 ? -30.689 36.734  24.984 1.00 30.18 ?  128  ASN A HB3  1 
ATOM   1762  H HD21 . ASN A 1 162 ? -30.996 38.516  26.397 1.00 66.91 ?  128  ASN A HD21 1 
ATOM   1763  H HD22 . ASN A 1 162 ? -31.788 39.712  25.998 1.00 66.91 ?  128  ASN A HD22 1 
ATOM   1764  N N    . ASN A 1 163 ? -29.973 35.933  21.565 1.00 20.47 ?  129  ASN A N    1 
ATOM   1765  C CA   . ASN A 1 163 ? -28.895 36.316  20.664 1.00 18.29 ?  129  ASN A CA   1 
ATOM   1766  C C    . ASN A 1 163 ? -27.587 36.613  21.391 1.00 24.58 ?  129  ASN A C    1 
ATOM   1767  O O    . ASN A 1 163 ? -26.761 37.395  20.910 1.00 22.35 ?  129  ASN A O    1 
ATOM   1768  C CB   . ASN A 1 163 ? -29.297 37.496  19.770 1.00 22.52 ?  129  ASN A CB   1 
ATOM   1769  C CG   . ASN A 1 163 ? -28.361 37.676  18.595 1.00 32.20 ?  129  ASN A CG   1 
ATOM   1770  O OD1  . ASN A 1 163 ? -27.965 36.700  17.944 1.00 39.84 ?  129  ASN A OD1  1 
ATOM   1771  N ND2  . ASN A 1 163 ? -27.972 38.924  18.331 1.00 37.09 ?  129  ASN A ND2  1 
ATOM   1772  H H    . ASN A 1 163 ? -30.220 35.115  21.472 1.00 24.57 ?  129  ASN A H    1 
ATOM   1773  H HA   . ASN A 1 163 ? -28.719 35.555  20.088 1.00 21.95 ?  129  ASN A HA   1 
ATOM   1774  H HB2  . ASN A 1 163 ? -30.190 37.341  19.422 1.00 27.02 ?  129  ASN A HB2  1 
ATOM   1775  H HB3  . ASN A 1 163 ? -29.283 38.311  20.295 1.00 27.02 ?  129  ASN A HB3  1 
ATOM   1776  H HD21 . ASN A 1 163 ? -28.254 39.574  18.818 1.00 44.51 ?  129  ASN A HD21 1 
ATOM   1777  H HD22 . ASN A 1 163 ? -27.440 39.078  17.673 1.00 44.51 ?  129  ASN A HD22 1 
ATOM   1778  N N    . GLU A 1 164 ? -27.343 35.976  22.538 1.00 19.41 ?  130  GLU A N    1 
ATOM   1779  C CA   . GLU A 1 164 ? -26.094 36.174  23.267 1.00 18.76 ?  130  GLU A CA   1 
ATOM   1780  C C    . GLU A 1 164 ? -25.228 34.916  23.176 1.00 14.77 ?  130  GLU A C    1 
ATOM   1781  O O    . GLU A 1 164 ? -25.732 33.808  23.308 1.00 15.97 ?  130  GLU A O    1 
ATOM   1782  C CB   . GLU A 1 164 ? -26.336 36.489  24.741 1.00 20.96 ?  130  GLU A CB   1 
ATOM   1783  C CG   . GLU A 1 164 ? -27.325 37.659  24.968 1.00 23.90 ?  130  GLU A CG   1 
ATOM   1784  C CD   . GLU A 1 164 ? -27.869 37.713  26.389 1.00 35.96 ?  130  GLU A CD   1 
ATOM   1785  O OE1  . GLU A 1 164 ? -28.017 36.664  27.047 1.00 31.87 ?  130  GLU A OE1  1 
ATOM   1786  O OE2  . GLU A 1 164 ? -28.198 38.826  26.843 1.00 41.17 ?  130  GLU A OE2  1 
ATOM   1787  H H    . GLU A 1 164 ? -27.887 35.424  22.912 1.00 23.29 ?  130  GLU A H    1 
ATOM   1788  H HA   . GLU A 1 164 ? -25.623 36.921  22.864 1.00 22.51 ?  130  GLU A HA   1 
ATOM   1789  H HB2  . GLU A 1 164 ? -26.702 35.702  25.173 1.00 25.15 ?  130  GLU A HB2  1 
ATOM   1790  H HB3  . GLU A 1 164 ? -25.491 36.730  25.152 1.00 25.15 ?  130  GLU A HB3  1 
ATOM   1791  H HG2  . GLU A 1 164 ? -26.869 38.496  24.791 1.00 28.68 ?  130  GLU A HG2  1 
ATOM   1792  H HG3  . GLU A 1 164 ? -28.077 37.557  24.364 1.00 28.68 ?  130  GLU A HG3  1 
ATOM   1793  N N    . LEU A 1 165 ? -23.929 35.131  23.007 1.00 15.35 ?  131  LEU A N    1 
ATOM   1794  C CA   . LEU A 1 165 ? -23.001 33.995  23.051 1.00 14.81 ?  131  LEU A CA   1 
ATOM   1795  C C    . LEU A 1 165 ? -23.067 33.324  24.411 1.00 14.39 ?  131  LEU A C    1 
ATOM   1796  O O    . LEU A 1 165 ? -23.190 33.990  25.450 1.00 15.86 ?  131  LEU A O    1 
ATOM   1797  C CB   . LEU A 1 165 ? -21.591 34.475  22.809 1.00 14.57 ?  131  LEU A CB   1 
ATOM   1798  C CG   . LEU A 1 165 ? -21.273 34.888  21.374 1.00 16.25 ?  131  LEU A CG   1 
ATOM   1799  C CD1  . LEU A 1 165 ? -19.942 35.594  21.296 1.00 19.10 ?  131  LEU A CD1  1 
ATOM   1800  C CD2  . LEU A 1 165 ? -21.249 33.660  20.457 1.00 18.15 ?  131  LEU A CD2  1 
ATOM   1801  H H    . LEU A 1 165 ? -23.565 35.898  22.869 1.00 18.42 ?  131  LEU A H    1 
ATOM   1802  H HA   . LEU A 1 165 ? -23.241 33.353  22.364 1.00 17.77 ?  131  LEU A HA   1 
ATOM   1803  H HB2  . LEU A 1 165 ? -21.431 35.247  23.375 1.00 17.48 ?  131  LEU A HB2  1 
ATOM   1804  H HB3  . LEU A 1 165 ? -20.981 33.759  23.046 1.00 17.48 ?  131  LEU A HB3  1 
ATOM   1805  H HG   . LEU A 1 165 ? -21.965 35.498  21.074 1.00 19.49 ?  131  LEU A HG   1 
ATOM   1806  H HD11 . LEU A 1 165 ? -19.796 35.893  20.385 1.00 22.92 ?  131  LEU A HD11 1 
ATOM   1807  H HD12 . LEU A 1 165 ? -19.953 36.355  21.897 1.00 22.92 ?  131  LEU A HD12 1 
ATOM   1808  H HD13 . LEU A 1 165 ? -19.241 34.976  21.558 1.00 22.92 ?  131  LEU A HD13 1 
ATOM   1809  H HD21 . LEU A 1 165 ? -21.044 33.946  19.553 1.00 21.78 ?  131  LEU A HD21 1 
ATOM   1810  H HD22 . LEU A 1 165 ? -20.570 33.044  20.772 1.00 21.78 ?  131  LEU A HD22 1 
ATOM   1811  H HD23 . LEU A 1 165 ? -22.119 33.233  20.479 1.00 21.78 ?  131  LEU A HD23 1 
ATOM   1812  N N    . VAL A 1 166 ? -23.003 32.011  24.411 1.00 12.82 ?  132  VAL A N    1 
ATOM   1813  C CA   . VAL A 1 166 ? -22.960 31.213  25.638 1.00 12.61 ?  132  VAL A CA   1 
ATOM   1814  C C    . VAL A 1 166 ? -21.577 30.558  25.765 1.00 12.28 ?  132  VAL A C    1 
ATOM   1815  O O    . VAL A 1 166 ? -20.850 30.356  24.779 1.00 12.42 ?  132  VAL A O    1 
ATOM   1816  C CB   . VAL A 1 166 ? -24.099 30.181  25.751 1.00 14.87 ?  132  VAL A CB   1 
ATOM   1817  C CG1  . VAL A 1 166 ? -25.421 30.892  25.741 1.00 16.44 ?  132  VAL A CG1  1 
ATOM   1818  C CG2  . VAL A 1 166 ? -24.036 29.177  24.636 1.00 15.01 ?  132  VAL A CG2  1 
ATOM   1819  H H    . VAL A 1 166 ? -22.983 31.535  23.695 1.00 15.39 ?  132  VAL A H    1 
ATOM   1820  H HA   . VAL A 1 166 ? -23.068 31.817  26.389 1.00 15.14 ?  132  VAL A HA   1 
ATOM   1821  H HB   . VAL A 1 166 ? -24.004 29.695  26.585 1.00 17.85 ?  132  VAL A HB   1 
ATOM   1822  H HG11 . VAL A 1 166 ? -26.126 30.251  25.921 1.00 19.73 ?  132  VAL A HG11 1 
ATOM   1823  H HG12 . VAL A 1 166 ? -25.415 31.579  26.425 1.00 19.73 ?  132  VAL A HG12 1 
ATOM   1824  H HG13 . VAL A 1 166 ? -25.556 31.295  24.869 1.00 19.73 ?  132  VAL A HG13 1 
ATOM   1825  H HG21 . VAL A 1 166 ? -24.797 28.578  24.707 1.00 18.01 ?  132  VAL A HG21 1 
ATOM   1826  H HG22 . VAL A 1 166 ? -24.061 29.645  23.787 1.00 18.01 ?  132  VAL A HG22 1 
ATOM   1827  H HG23 . VAL A 1 166 ? -23.211 28.673  24.712 1.00 18.01 ?  132  VAL A HG23 1 
ATOM   1828  N N    . TYR A 1 167 ? -21.197 30.244  27.012 1.00 12.98 ?  133  TYR A N    1 
ATOM   1829  C CA   . TYR A 1 167 ? -19.816 29.887  27.339 1.00 11.65 ?  133  TYR A CA   1 
ATOM   1830  C C    . TYR A 1 167 ? -19.757 28.724  28.297 1.00 12.30 ?  133  TYR A C    1 
ATOM   1831  O O    . TYR A 1 167 ? -20.690 28.425  29.044 1.00 12.63 ?  133  TYR A O    1 
ATOM   1832  C CB   . TYR A 1 167 ? -19.085 31.098  27.978 1.00 13.09 ?  133  TYR A CB   1 
ATOM   1833  C CG   . TYR A 1 167 ? -18.925 32.232  27.026 1.00 12.15 ?  133  TYR A CG   1 
ATOM   1834  C CD1  . TYR A 1 167 ? -17.896 32.255  26.137 1.00 13.67 ?  133  TYR A CD1  1 
ATOM   1835  C CD2  . TYR A 1 167 ? -19.834 33.302  27.006 1.00 14.48 ?  133  TYR A CD2  1 
ATOM   1836  C CE1  . TYR A 1 167 ? -17.739 33.253  25.224 1.00 16.05 ?  133  TYR A CE1  1 
ATOM   1837  C CE2  . TYR A 1 167 ? -19.665 34.343  26.100 1.00 16.01 ?  133  TYR A CE2  1 
ATOM   1838  C CZ   . TYR A 1 167 ? -18.607 34.298  25.222 1.00 16.59 ?  133  TYR A CZ   1 
ATOM   1839  O OH   . TYR A 1 167 ? -18.422 35.317  24.271 1.00 21.36 ?  133  TYR A OH   1 
ATOM   1840  H H    . TYR A 1 167 ? -21.727 30.232  27.689 1.00 15.58 ?  133  TYR A H    1 
ATOM   1841  H HA   . TYR A 1 167 ? -19.374 29.606  26.522 1.00 13.98 ?  133  TYR A HA   1 
ATOM   1842  H HB2  . TYR A 1 167 ? -19.598 31.413  28.739 1.00 15.71 ?  133  TYR A HB2  1 
ATOM   1843  H HB3  . TYR A 1 167 ? -18.201 30.819  28.266 1.00 15.71 ?  133  TYR A HB3  1 
ATOM   1844  H HD1  . TYR A 1 167 ? -17.275 31.562  26.153 1.00 16.41 ?  133  TYR A HD1  1 
ATOM   1845  H HD2  . TYR A 1 167 ? -20.550 33.314  27.600 1.00 17.38 ?  133  TYR A HD2  1 
ATOM   1846  H HE1  . TYR A 1 167 ? -17.044 33.220  24.607 1.00 19.25 ?  133  TYR A HE1  1 
ATOM   1847  H HE2  . TYR A 1 167 ? -20.258 35.059  26.087 1.00 19.21 ?  133  TYR A HE2  1 
ATOM   1848  H HH   . TYR A 1 167 ? -17.774 35.128  23.771 1.00 25.63 ?  133  TYR A HH   1 
ATOM   1849  N N    . MET A 1 168 ? -18.558 28.109  28.311 1.00 11.55 ?  134  MET A N    1 
ATOM   1850  C CA   . MET A 1 168 ? -18.160 27.153  29.319 1.00 11.72 ?  134  MET A CA   1 
ATOM   1851  C C    . MET A 1 168 ? -17.980 27.882  30.656 1.00 11.00 ?  134  MET A C    1 
ATOM   1852  O O    . MET A 1 168 ? -18.102 29.101  30.733 1.00 11.48 ?  134  MET A O    1 
ATOM   1853  C CB   . MET A 1 168 ? -16.828 26.543  28.905 1.00 11.18 ?  134  MET A CB   1 
ATOM   1854  C CG   . MET A 1 168 ? -16.956 25.555  27.753 1.00 13.44 ?  134  MET A CG   1 
ATOM   1855  S SD   . MET A 1 168 ? -17.840 24.038  28.287 1.00 12.15 ?  134  MET A SD   1 
ATOM   1856  C CE   . MET A 1 168 ? -16.528 23.233  29.158 1.00 12.95 ?  134  MET A CE   1 
ATOM   1857  H H    . MET A 1 168 ? -17.948 28.244  27.720 1.00 13.87 ?  134  MET A H    1 
ATOM   1858  H HA   . MET A 1 168 ? -18.829 26.456  29.406 1.00 14.06 ?  134  MET A HA   1 
ATOM   1859  H HB2  . MET A 1 168 ? -16.231 27.254  28.624 1.00 13.41 ?  134  MET A HB2  1 
ATOM   1860  H HB3  . MET A 1 168 ? -16.449 26.071  29.663 1.00 13.41 ?  134  MET A HB3  1 
ATOM   1861  H HG2  . MET A 1 168 ? -17.457 25.964  27.030 1.00 16.12 ?  134  MET A HG2  1 
ATOM   1862  H HG3  . MET A 1 168 ? -16.072 25.303  27.444 1.00 16.12 ?  134  MET A HG3  1 
ATOM   1863  H HE1  . MET A 1 168 ? -16.859 22.398  29.526 1.00 15.54 ?  134  MET A HE1  1 
ATOM   1864  H HE2  . MET A 1 168 ? -15.801 23.056  28.541 1.00 15.54 ?  134  MET A HE2  1 
ATOM   1865  H HE3  . MET A 1 168 ? -16.222 23.812  29.873 1.00 15.54 ?  134  MET A HE3  1 
ATOM   1866  N N    . PRO A 1 169 ? -17.711 27.151  31.735 1.00 10.82 ?  135  PRO A N    1 
ATOM   1867  C CA   . PRO A 1 169 ? -17.621 27.804  33.062 1.00 11.58 ?  135  PRO A CA   1 
ATOM   1868  C C    . PRO A 1 169 ? -16.559 28.856  33.169 1.00 12.04 ?  135  PRO A C    1 
ATOM   1869  O O    . PRO A 1 169 ? -16.716 29.759  34.018 1.00 13.30 ?  135  PRO A O    1 
ATOM   1870  C CB   . PRO A 1 169 ? -17.384 26.622  34.015 1.00 13.57 ?  135  PRO A CB   1 
ATOM   1871  C CG   . PRO A 1 169 ? -18.073 25.454  33.317 1.00 13.79 ?  135  PRO A CG   1 
ATOM   1872  C CD   . PRO A 1 169 ? -17.706 25.673  31.868 1.00 12.42 ?  135  PRO A CD   1 
ATOM   1873  H HA   . PRO A 1 169 ? -18.469 28.219  33.285 1.00 13.89 ?  135  PRO A HA   1 
ATOM   1874  H HB2  . PRO A 1 169 ? -16.434 26.459  34.118 1.00 16.28 ?  135  PRO A HB2  1 
ATOM   1875  H HB3  . PRO A 1 169 ? -17.786 26.802  34.879 1.00 16.28 ?  135  PRO A HB3  1 
ATOM   1876  H HG2  . PRO A 1 169 ? -17.728 24.610  33.647 1.00 16.54 ?  135  PRO A HG2  1 
ATOM   1877  H HG3  . PRO A 1 169 ? -19.032 25.496  33.451 1.00 16.54 ?  135  PRO A HG3  1 
ATOM   1878  H HD2  . PRO A 1 169 ? -16.826 25.312  31.677 1.00 14.91 ?  135  PRO A HD2  1 
ATOM   1879  H HD3  . PRO A 1 169 ? -18.365 25.271  31.281 1.00 14.91 ?  135  PRO A HD3  1 
ATOM   1880  N N    . ASN A 1 170 ? -15.515 28.850  32.343 1.00 11.23 ?  136  ASN A N    1 
ATOM   1881  C CA   . ASN A 1 170 ? -14.533 29.928  32.364 1.00 12.04 ?  136  ASN A CA   1 
ATOM   1882  C C    . ASN A 1 170 ? -15.071 31.247  31.828 1.00 11.06 ?  136  ASN A C    1 
ATOM   1883  O O    . ASN A 1 170 ? -14.395 32.273  31.950 1.00 13.37 ?  136  ASN A O    1 
ATOM   1884  C CB   . ASN A 1 170 ? -13.231 29.535  31.657 1.00 13.74 ?  136  ASN A CB   1 
ATOM   1885  C CG   . ASN A 1 170 ? -13.419 29.188  30.204 1.00 12.52 ?  136  ASN A CG   1 
ATOM   1886  O OD1  . ASN A 1 170 ? -14.374 29.625  29.568 1.00 11.64 ?  136  ASN A OD1  1 
ATOM   1887  N ND2  . ASN A 1 170 ? -12.489 28.376  29.665 1.00 16.50 ?  136  ASN A ND2  1 
ATOM   1888  H H    . ASN A 1 170 ? -15.354 28.235  31.764 1.00 13.48 ?  136  ASN A H    1 
ATOM   1889  H HA   . ASN A 1 170 ? -14.289 30.076  33.291 1.00 14.45 ?  136  ASN A HA   1 
ATOM   1890  H HB2  . ASN A 1 170 ? -12.610 30.278  31.707 1.00 16.48 ?  136  ASN A HB2  1 
ATOM   1891  H HB3  . ASN A 1 170 ? -12.855 28.758  32.101 1.00 16.48 ?  136  ASN A HB3  1 
ATOM   1892  H HD21 . ASN A 1 170 ? -12.547 28.146  28.838 1.00 19.80 ?  136  ASN A HD21 1 
ATOM   1893  H HD22 . ASN A 1 170 ? -11.838 28.089  30.147 1.00 19.80 ?  136  ASN A HD22 1 
ATOM   1894  N N    . GLY A 1 171 ? -16.264 31.254  31.243 1.00 11.83 ?  137  GLY A N    1 
ATOM   1895  C CA   . GLY A 1 171 ? -16.847 32.494  30.745 1.00 12.04 ?  137  GLY A CA   1 
ATOM   1896  C C    . GLY A 1 171 ? -16.249 33.026  29.492 1.00 13.13 ?  137  GLY A C    1 
ATOM   1897  O O    . GLY A 1 171 ? -16.577 34.165  29.099 1.00 13.04 ?  137  GLY A O    1 
ATOM   1898  H H    . GLY A 1 171 ? -16.754 30.558  31.122 1.00 14.20 ?  137  GLY A H    1 
ATOM   1899  H HA2  . GLY A 1 171 ? -17.791 32.345  30.579 1.00 14.44 ?  137  GLY A HA2  1 
ATOM   1900  H HA3  . GLY A 1 171 ? -16.750 33.176  31.428 1.00 14.44 ?  137  GLY A HA3  1 
ATOM   1901  N N    . SER A 1 172 ? -15.360 32.283  28.839 1.00 11.31 ?  138  SER A N    1 
ATOM   1902  C CA   . SER A 1 172 ? -14.653 32.758  27.660 1.00 11.92 ?  138  SER A CA   1 
ATOM   1903  C C    . SER A 1 172 ? -14.562 31.753  26.531 1.00 12.41 ?  138  SER A C    1 
ATOM   1904  O O    . SER A 1 172 ? -14.463 32.171  25.375 1.00 13.26 ?  138  SER A O    1 
ATOM   1905  C CB   . SER A 1 172 ? -13.251 33.259  28.028 1.00 19.53 ?  138  SER A CB   1 
ATOM   1906  O OG   . SER A 1 172 ? -12.504 32.275  28.609 1.00 28.74 ?  138  SER A OG   1 
ATOM   1907  H H    . SER A 1 172 ? -15.145 31.482  29.066 1.00 13.58 ?  138  SER A H    1 
ATOM   1908  H HA   . SER A 1 172 ? -15.136 33.522  27.306 1.00 14.31 ?  138  SER A HA   1 
ATOM   1909  H HB2  . SER A 1 172 ? -12.803 33.556  27.221 1.00 23.44 ?  138  SER A HB2  1 
ATOM   1910  H HB3  . SER A 1 172 ? -13.335 33.997  28.651 1.00 23.44 ?  138  SER A HB3  1 
ATOM   1911  H HG   . SER A 1 172 ? -11.705 32.524  28.680 1.00 34.48 ?  138  SER A HG   1 
ATOM   1912  N N    . THR A 1 173 ? -14.611 30.434  26.802 1.00 11.97 ?  139  THR A N    1 
ATOM   1913  C CA   . THR A 1 173 ? -14.577 29.437  25.736 1.00 11.66 ?  139  THR A CA   1 
ATOM   1914  C C    . THR A 1 173 ? -16.011 29.224  25.238 1.00 11.35 ?  139  THR A C    1 
ATOM   1915  O O    . THR A 1 173 ? -16.858 28.794  26.014 1.00 11.62 ?  139  THR A O    1 
ATOM   1916  C CB   . THR A 1 173 ? -14.002 28.142  26.256 1.00 9.96  ?  139  THR A CB   1 
ATOM   1917  O OG1  . THR A 1 173 ? -12.693 28.362  26.787 1.00 12.25 ?  139  THR A OG1  1 
ATOM   1918  C CG2  . THR A 1 173 ? -13.940 27.088  25.163 1.00 12.64 ?  139  THR A CG2  1 
ATOM   1919  H H    . THR A 1 173 ? -14.664 30.102  27.593 1.00 14.37 ?  139  THR A H    1 
ATOM   1920  H HA   . THR A 1 173 ? -14.026 29.735  24.995 1.00 13.99 ?  139  THR A HA   1 
ATOM   1921  H HB   . THR A 1 173 ? -14.579 27.806  26.960 1.00 11.96 ?  139  THR A HB   1 
ATOM   1922  H HG1  . THR A 1 173 ? -12.220 28.770  26.225 1.00 14.70 ?  139  THR A HG1  1 
ATOM   1923  H HG21 . THR A 1 173 ? -13.611 26.251  25.528 1.00 15.16 ?  139  THR A HG21 1 
ATOM   1924  H HG22 . THR A 1 173 ? -14.823 26.943  24.791 1.00 15.16 ?  139  THR A HG22 1 
ATOM   1925  H HG23 . THR A 1 173 ? -13.343 27.379  24.456 1.00 15.16 ?  139  THR A HG23 1 
ATOM   1926  N N    . PRO A 1 174 ? -16.291 29.518  23.974 1.00 11.03 ?  140  PRO A N    1 
ATOM   1927  C CA   . PRO A 1 174 ? -17.642 29.370  23.418 1.00 10.56 ?  140  PRO A CA   1 
ATOM   1928  C C    . PRO A 1 174 ? -17.808 28.020  22.748 1.00 10.55 ?  140  PRO A C    1 
ATOM   1929  O O    . PRO A 1 174 ? -16.921 27.141  22.842 1.00 11.78 ?  140  PRO A O    1 
ATOM   1930  C CB   . PRO A 1 174 ? -17.705 30.500  22.390 1.00 11.74 ?  140  PRO A CB   1 
ATOM   1931  C CG   . PRO A 1 174 ? -16.283 30.521  21.795 1.00 12.41 ?  140  PRO A CG   1 
ATOM   1932  C CD   . PRO A 1 174 ? -15.359 30.107  22.980 1.00 11.62 ?  140  PRO A CD   1 
ATOM   1933  H HA   . PRO A 1 174 ? -18.324 29.501  24.095 1.00 12.68 ?  140  PRO A HA   1 
ATOM   1934  H HB2  . PRO A 1 174 ? -18.368 30.300  21.712 1.00 14.09 ?  140  PRO A HB2  1 
ATOM   1935  H HB3  . PRO A 1 174 ? -17.917 31.340  22.826 1.00 14.09 ?  140  PRO A HB3  1 
ATOM   1936  H HG2  . PRO A 1 174 ? -16.218 29.886  21.065 1.00 14.89 ?  140  PRO A HG2  1 
ATOM   1937  H HG3  . PRO A 1 174 ? -16.067 31.412  21.480 1.00 14.89 ?  140  PRO A HG3  1 
ATOM   1938  H HD2  . PRO A 1 174 ? -14.706 29.451  22.692 1.00 13.95 ?  140  PRO A HD2  1 
ATOM   1939  H HD3  . PRO A 1 174 ? -14.909 30.883  23.350 1.00 13.95 ?  140  PRO A HD3  1 
ATOM   1940  N N    . PHE A 1 175 ? -18.957 27.835  22.090 1.00 9.97  ?  141  PHE A N    1 
ATOM   1941  C CA   . PHE A 1 175 ? -19.300 26.585  21.435 1.00 10.66 ?  141  PHE A CA   1 
ATOM   1942  C C    . PHE A 1 175 ? -19.550 26.784  19.947 1.00 11.63 ?  141  PHE A C    1 
ATOM   1943  O O    . PHE A 1 175 ? -20.059 27.830  19.508 1.00 11.22 ?  141  PHE A O    1 
ATOM   1944  C CB   . PHE A 1 175 ? -20.592 25.995  22.017 1.00 11.83 ?  141  PHE A CB   1 
ATOM   1945  C CG   . PHE A 1 175 ? -20.571 25.780  23.508 1.00 10.39 ?  141  PHE A CG   1 
ATOM   1946  C CD1  . PHE A 1 175 ? -20.903 26.784  24.392 1.00 10.72 ?  141  PHE A CD1  1 
ATOM   1947  C CD2  . PHE A 1 175 ? -20.156 24.567  24.044 1.00 11.10 ?  141  PHE A CD2  1 
ATOM   1948  C CE1  . PHE A 1 175 ? -20.936 26.558  25.769 1.00 13.10 ?  141  PHE A CE1  1 
ATOM   1949  C CE2  . PHE A 1 175 ? -20.165 24.365  25.426 1.00 11.26 ?  141  PHE A CE2  1 
ATOM   1950  C CZ   . PHE A 1 175 ? -20.547 25.365  26.270 1.00 10.66 ?  141  PHE A CZ   1 
ATOM   1951  H H    . PHE A 1 175 ? -19.565 28.439  22.011 1.00 11.96 ?  141  PHE A H    1 
ATOM   1952  H HA   . PHE A 1 175 ? -18.552 25.978  21.555 1.00 12.79 ?  141  PHE A HA   1 
ATOM   1953  H HB2  . PHE A 1 175 ? -21.323 26.601  21.821 1.00 14.20 ?  141  PHE A HB2  1 
ATOM   1954  H HB3  . PHE A 1 175 ? -20.753 25.134  21.600 1.00 14.20 ?  141  PHE A HB3  1 
ATOM   1955  H HD1  . PHE A 1 175 ? -21.109 27.629  24.065 1.00 12.86 ?  141  PHE A HD1  1 
ATOM   1956  H HD2  . PHE A 1 175 ? -19.870 23.886  23.480 1.00 13.32 ?  141  PHE A HD2  1 
ATOM   1957  H HE1  . PHE A 1 175 ? -21.226 27.230  26.342 1.00 15.72 ?  141  PHE A HE1  1 
ATOM   1958  H HE2  . PHE A 1 175 ? -19.909 23.542  25.773 1.00 13.52 ?  141  PHE A HE2  1 
ATOM   1959  H HZ   . PHE A 1 175 ? -20.540 25.227  27.189 1.00 12.80 ?  141  PHE A HZ   1 
ATOM   1960  N N    . PHE A 1 176 ? -19.215 25.762  19.159 1.00 11.26 ?  142  PHE A N    1 
ATOM   1961  C CA   . PHE A 1 176 ? -19.630 25.748  17.753 1.00 11.80 ?  142  PHE A CA   1 
ATOM   1962  C C    . PHE A 1 176 ? -21.139 25.553  17.676 1.00 12.60 ?  142  PHE A C    1 
ATOM   1963  O O    . PHE A 1 176 ? -21.696 24.668  18.331 1.00 13.97 ?  142  PHE A O    1 
ATOM   1964  C CB   . PHE A 1 176 ? -18.977 24.563  17.038 1.00 11.99 ?  142  PHE A CB   1 
ATOM   1965  C CG   . PHE A 1 176 ? -17.468 24.546  17.063 1.00 12.15 ?  142  PHE A CG   1 
ATOM   1966  C CD1  . PHE A 1 176 ? -16.735 25.532  16.472 1.00 15.47 ?  142  PHE A CD1  1 
ATOM   1967  C CD2  . PHE A 1 176 ? -16.799 23.448  17.587 1.00 12.81 ?  142  PHE A CD2  1 
ATOM   1968  C CE1  . PHE A 1 176 ? -15.342 25.472  16.492 1.00 15.45 ?  142  PHE A CE1  1 
ATOM   1969  C CE2  . PHE A 1 176 ? -15.396 23.391  17.582 1.00 14.81 ?  142  PHE A CE2  1 
ATOM   1970  C CZ   . PHE A 1 176 ? -14.699 24.393  17.034 1.00 15.10 ?  142  PHE A CZ   1 
ATOM   1971  H H    . PHE A 1 176 ? -18.758 25.078  19.408 1.00 13.51 ?  142  PHE A H    1 
ATOM   1972  H HA   . PHE A 1 176 ? -19.370 26.579  17.326 1.00 14.16 ?  142  PHE A HA   1 
ATOM   1973  H HB2  . PHE A 1 176 ? -19.283 23.745  17.460 1.00 14.39 ?  142  PHE A HB2  1 
ATOM   1974  H HB3  . PHE A 1 176 ? -19.251 24.578  16.108 1.00 14.39 ?  142  PHE A HB3  1 
ATOM   1975  H HD1  . PHE A 1 176 ? -17.164 26.245  16.055 1.00 18.56 ?  142  PHE A HD1  1 
ATOM   1976  H HD2  . PHE A 1 176 ? -17.286 22.741  17.946 1.00 15.37 ?  142  PHE A HD2  1 
ATOM   1977  H HE1  . PHE A 1 176 ? -14.846 26.173  16.134 1.00 18.54 ?  142  PHE A HE1  1 
ATOM   1978  H HE2  . PHE A 1 176 ? -14.955 22.663  17.957 1.00 17.77 ?  142  PHE A HE2  1 
ATOM   1979  H HZ   . PHE A 1 176 ? -13.770 24.355  17.021 1.00 18.11 ?  142  PHE A HZ   1 
ATOM   1980  N N    . ASP A 1 177 ? -21.810 26.334  16.821 1.00 11.48 ?  143  ASP A N    1 
ATOM   1981  C CA   . ASP A 1 177 ? -23.235 26.062  16.530 1.00 11.78 ?  143  ASP A CA   1 
ATOM   1982  C C    . ASP A 1 177 ? -23.324 25.043  15.411 1.00 11.02 ?  143  ASP A C    1 
ATOM   1983  O O    . ASP A 1 177 ? -23.374 25.403  14.223 1.00 13.06 ?  143  ASP A O    1 
ATOM   1984  C CB   . ASP A 1 177 ? -24.021 27.317  16.177 1.00 12.53 ?  143  ASP A CB   1 
ATOM   1985  C CG   . ASP A 1 177 ? -25.500 27.004  16.026 1.00 11.32 ?  143  ASP A CG   1 
ATOM   1986  O OD1  . ASP A 1 177 ? -25.831 25.842  16.081 1.00 12.22 ?  143  ASP A OD1  1 
ATOM   1987  O OD2  . ASP A 1 177 ? -26.280 27.976  15.885 1.00 12.97 ?  143  ASP A OD2  1 
ATOM   1988  H H    . ASP A 1 177 ? -21.476 27.008  16.405 1.00 13.78 ?  143  ASP A H    1 
ATOM   1989  H HA   . ASP A 1 177 ? -23.617 25.688  17.339 1.00 14.13 ?  143  ASP A HA   1 
ATOM   1990  H HB2  . ASP A 1 177 ? -23.916 27.974  16.883 1.00 15.04 ?  143  ASP A HB2  1 
ATOM   1991  H HB3  . ASP A 1 177 ? -23.696 27.677  15.337 1.00 15.04 ?  143  ASP A HB3  1 
ATOM   1992  N N    . ILE A 1 178 ? -23.299 23.773  15.785 1.00 11.74 ?  144  ILE A N    1 
ATOM   1993  C CA   . ILE A 1 178 ? -23.231 22.693  14.813 1.00 11.63 ?  144  ILE A CA   1 
ATOM   1994  C C    . ILE A 1 178 ? -24.566 22.524  14.085 1.00 12.39 ?  144  ILE A C    1 
ATOM   1995  O O    . ILE A 1 178 ? -24.647 21.670  13.199 1.00 13.23 ?  144  ILE A O    1 
ATOM   1996  C CB   . ILE A 1 178 ? -22.750 21.373  15.445 1.00 11.68 ?  144  ILE A CB   1 
ATOM   1997  C CG1  . ILE A 1 178 ? -23.665 20.906  16.563 1.00 11.95 ?  144  ILE A CG1  1 
ATOM   1998  C CG2  . ILE A 1 178 ? -21.303 21.541  15.943 1.00 12.98 ?  144  ILE A CG2  1 
ATOM   1999  C CD1  . ILE A 1 178 ? -23.384 19.480  16.980 1.00 14.26 ?  144  ILE A CD1  1 
ATOM   2000  H H    . ILE A 1 178 ? -23.321 23.508  16.603 1.00 14.09 ?  144  ILE A H    1 
ATOM   2001  H HA   . ILE A 1 178 ? -22.579 22.949  14.142 1.00 13.96 ?  144  ILE A HA   1 
ATOM   2002  H HB   . ILE A 1 178 ? -22.778 20.684  14.763 1.00 14.02 ?  144  ILE A HB   1 
ATOM   2003  H HG12 . ILE A 1 178 ? -23.538 21.478  17.336 1.00 14.34 ?  144  ILE A HG12 1 
ATOM   2004  H HG13 . ILE A 1 178 ? -24.586 20.957  16.260 1.00 14.34 ?  144  ILE A HG13 1 
ATOM   2005  H HG21 . ILE A 1 178 ? -20.982 20.688  16.276 1.00 15.58 ?  144  ILE A HG21 1 
ATOM   2006  H HG22 . ILE A 1 178 ? -20.747 21.837  15.205 1.00 15.58 ?  144  ILE A HG22 1 
ATOM   2007  H HG23 . ILE A 1 178 ? -21.288 22.200  16.654 1.00 15.58 ?  144  ILE A HG23 1 
ATOM   2008  H HD11 . ILE A 1 178 ? -24.078 19.187  17.592 1.00 17.11 ?  144  ILE A HD11 1 
ATOM   2009  H HD12 . ILE A 1 178 ? -23.378 18.915  16.192 1.00 17.11 ?  144  ILE A HD12 1 
ATOM   2010  H HD13 . ILE A 1 178 ? -22.520 19.444  17.419 1.00 17.11 ?  144  ILE A HD13 1 
ATOM   2011  N N    . THR A 1 179 ? -25.601 23.301  14.439 1.00 12.55 ?  145  THR A N    1 
ATOM   2012  C CA   . THR A 1 179 ? -26.856 23.243  13.669 1.00 11.70 ?  145  THR A CA   1 
ATOM   2013  C C    . THR A 1 179 ? -26.708 23.913  12.310 1.00 13.95 ?  145  THR A C    1 
ATOM   2014  O O    . THR A 1 179 ? -27.547 23.683  11.431 1.00 13.59 ?  145  THR A O    1 
ATOM   2015  C CB   . THR A 1 179 ? -28.028 23.901  14.410 1.00 12.56 ?  145  THR A CB   1 
ATOM   2016  O OG1  . THR A 1 179 ? -27.838 25.315  14.451 1.00 13.05 ?  145  THR A OG1  1 
ATOM   2017  C CG2  . THR A 1 179 ? -28.186 23.334  15.795 1.00 13.46 ?  145  THR A CG2  1 
ATOM   2018  H H    . THR A 1 179 ? -25.603 23.853  15.098 1.00 15.06 ?  145  THR A H    1 
ATOM   2019  H HA   . THR A 1 179 ? -27.080 22.306  13.559 1.00 14.04 ?  145  THR A HA   1 
ATOM   2020  H HB   . THR A 1 179 ? -28.855 23.716  13.938 1.00 15.07 ?  145  THR A HB   1 
ATOM   2021  H HG1  . THR A 1 179 ? -27.193 25.503  14.955 1.00 15.67 ?  145  THR A HG1  1 
ATOM   2022  H HG21 . THR A 1 179 ? -29.040 23.605  16.168 1.00 16.15 ?  145  THR A HG21 1 
ATOM   2023  H HG22 . THR A 1 179 ? -28.150 22.365  15.763 1.00 16.15 ?  145  THR A HG22 1 
ATOM   2024  H HG23 . THR A 1 179 ? -27.474 23.657  16.369 1.00 16.15 ?  145  THR A HG23 1 
ATOM   2025  N N    . LYS A 1 180 ? -25.687 24.733  12.116 1.00 12.67 ?  146  LYS A N    1 
ATOM   2026  C CA   . LYS A 1 180 ? -25.444 25.441  10.863 1.00 13.18 ?  146  LYS A CA   1 
ATOM   2027  C C    . LYS A 1 180 ? -24.638 24.578  9.902  1.00 14.16 ?  146  LYS A C    1 
ATOM   2028  O O    . LYS A 1 180 ? -23.582 24.018  10.258 1.00 13.54 ?  146  LYS A O    1 
ATOM   2029  C CB   . LYS A 1 180 ? -24.733 26.760  11.146 1.00 14.13 ?  146  LYS A CB   1 
ATOM   2030  C CG   . LYS A 1 180 ? -25.674 27.738  11.906 1.00 16.59 ?  146  LYS A CG   1 
ATOM   2031  C CD   . LYS A 1 180 ? -25.087 29.084  12.125 1.00 15.77 ?  146  LYS A CD   1 
ATOM   2032  C CE   . LYS A 1 180 ? -26.163 30.134  12.425 1.00 19.11 ?  146  LYS A CE   1 
ATOM   2033  N NZ   . LYS A 1 180 ? -26.959 29.741  13.607 1.00 18.13 ?  146  LYS A NZ   1 
ATOM   2034  H H    . LYS A 1 180 ? -25.096 24.905  12.717 1.00 15.21 ?  146  LYS A H    1 
ATOM   2035  H HA   . LYS A 1 180 ? -26.289 25.631  10.427 1.00 15.82 ?  146  LYS A HA   1 
ATOM   2036  H HB2  . LYS A 1 180 ? -23.950 26.595  11.694 1.00 16.96 ?  146  LYS A HB2  1 
ATOM   2037  H HB3  . LYS A 1 180 ? -24.470 27.172  10.308 1.00 16.96 ?  146  LYS A HB3  1 
ATOM   2038  H HG2  . LYS A 1 180 ? -26.488 27.850  11.392 1.00 19.90 ?  146  LYS A HG2  1 
ATOM   2039  H HG3  . LYS A 1 180 ? -25.879 27.361  12.776 1.00 19.90 ?  146  LYS A HG3  1 
ATOM   2040  H HD2  . LYS A 1 180 ? -24.478 29.050  12.880 1.00 18.92 ?  146  LYS A HD2  1 
ATOM   2041  H HD3  . LYS A 1 180 ? -24.610 29.359  11.326 1.00 18.92 ?  146  LYS A HD3  1 
ATOM   2042  H HE2  . LYS A 1 180 ? -25.742 30.988  12.606 1.00 22.94 ?  146  LYS A HE2  1 
ATOM   2043  H HE3  . LYS A 1 180 ? -26.760 30.213  11.664 1.00 22.94 ?  146  LYS A HE3  1 
ATOM   2044  H HZ1  . LYS A 1 180 ? -27.550 30.377  13.801 1.00 21.76 ?  146  LYS A HZ1  1 
ATOM   2045  H HZ2  . LYS A 1 180 ? -27.393 28.982  13.443 1.00 21.76 ?  146  LYS A HZ2  1 
ATOM   2046  H HZ3  . LYS A 1 180 ? -26.423 29.622  14.308 1.00 21.76 ?  146  LYS A HZ3  1 
ATOM   2047  N N    . SER A 1 181 ? -25.158 24.448  8.675  1.00 13.70 ?  147  SER A N    1 
ATOM   2048  C CA   . SER A 1 181 ? -24.506 23.623  7.669  1.00 14.80 ?  147  SER A CA   1 
ATOM   2049  C C    . SER A 1 181 ? -23.036 23.981  7.514  1.00 11.95 ?  147  SER A C    1 
ATOM   2050  O O    . SER A 1 181 ? -22.188 23.074  7.421  1.00 13.54 ?  147  SER A O    1 
ATOM   2051  C CB   . SER A 1 181 ? -25.212 23.703  6.300  1.00 15.96 ?  147  SER A CB   1 
ATOM   2052  O OG   . SER A 1 181 ? -25.397 25.022  5.859  1.00 17.28 ?  147  SER A OG   1 
ATOM   2053  H H    . SER A 1 181 ? -25.882 24.827  8.407  1.00 16.44 ?  147  SER A H    1 
ATOM   2054  H HA   . SER A 1 181 ? -24.577 22.704  7.971  1.00 17.76 ?  147  SER A HA   1 
ATOM   2055  H HB2  . SER A 1 181 ? -24.671 23.233  5.646  1.00 19.16 ?  147  SER A HB2  1 
ATOM   2056  H HB3  . SER A 1 181 ? -26.082 23.280  6.377  1.00 19.16 ?  147  SER A HB3  1 
ATOM   2057  H HG   . SER A 1 181 ? -24.653 25.396  5.751  1.00 20.74 ?  147  SER A HG   1 
ATOM   2058  N N    . PHE A 1 182 ? -22.694 25.257  7.451  1.00 12.58 ?  148  PHE A N    1 
ATOM   2059  C CA   . PHE A 1 182 ? -21.298 25.567  7.130  1.00 12.28 ?  148  PHE A CA   1 
ATOM   2060  C C    . PHE A 1 182 ? -20.374 25.209  8.275  1.00 13.24 ?  148  PHE A C    1 
ATOM   2061  O O    . PHE A 1 182 ? -19.202 24.890  8.045  1.00 12.79 ?  148  PHE A O    1 
ATOM   2062  C CB   . PHE A 1 182 ? -21.106 27.017  6.681  1.00 12.92 ?  148  PHE A CB   1 
ATOM   2063  C CG   . PHE A 1 182 ? -20.997 28.037  7.799  1.00 13.32 ?  148  PHE A CG   1 
ATOM   2064  C CD1  . PHE A 1 182 ? -22.113 28.574  8.417  1.00 13.32 ?  148  PHE A CD1  1 
ATOM   2065  C CD2  . PHE A 1 182 ? -19.734 28.515  8.173  1.00 15.56 ?  148  PHE A CD2  1 
ATOM   2066  C CE1  . PHE A 1 182 ? -21.955 29.547  9.410  1.00 13.91 ?  148  PHE A CE1  1 
ATOM   2067  C CE2  . PHE A 1 182 ? -19.581 29.486  9.147  1.00 15.80 ?  148  PHE A CE2  1 
ATOM   2068  C CZ   . PHE A 1 182 ? -20.683 30.006  9.762  1.00 15.97 ?  148  PHE A CZ   1 
ATOM   2069  H H    . PHE A 1 182 ? -23.215 25.929  7.581  1.00 15.10 ?  148  PHE A H    1 
ATOM   2070  H HA   . PHE A 1 182 ? -21.048 25.030  6.362  1.00 14.73 ?  148  PHE A HA   1 
ATOM   2071  H HB2  . PHE A 1 182 ? -20.289 27.070  6.161  1.00 15.50 ?  148  PHE A HB2  1 
ATOM   2072  H HB3  . PHE A 1 182 ? -21.865 27.270  6.133  1.00 15.50 ?  148  PHE A HB3  1 
ATOM   2073  H HD1  . PHE A 1 182 ? -22.964 28.289  8.173  1.00 15.99 ?  148  PHE A HD1  1 
ATOM   2074  H HD2  . PHE A 1 182 ? -18.978 28.171  7.756  1.00 18.67 ?  148  PHE A HD2  1 
ATOM   2075  H HE1  . PHE A 1 182 ? -22.704 29.892  9.841  1.00 16.70 ?  148  PHE A HE1  1 
ATOM   2076  H HE2  . PHE A 1 182 ? -18.732 29.784  9.382  1.00 18.95 ?  148  PHE A HE2  1 
ATOM   2077  H HZ   . PHE A 1 182 ? -20.588 30.663  10.412 1.00 19.16 ?  148  PHE A HZ   1 
ATOM   2078  N N    . VAL A 1 183 ? -20.896 25.203  9.505  1.00 12.67 ?  149  VAL A N    1 
ATOM   2079  C CA   . VAL A 1 183 ? -20.107 24.746  10.651 1.00 12.58 ?  149  VAL A CA   1 
ATOM   2080  C C    . VAL A 1 183 ? -19.919 23.242  10.612 1.00 11.57 ?  149  VAL A C    1 
ATOM   2081  O O    . VAL A 1 183 ? -18.820 22.739  10.869 1.00 12.25 ?  149  VAL A O    1 
ATOM   2082  C CB   . VAL A 1 183 ? -20.779 25.212  11.949 1.00 11.59 ?  149  VAL A CB   1 
ATOM   2083  C CG1  . VAL A 1 183 ? -20.026 24.663  13.148 1.00 12.84 ?  149  VAL A CG1  1 
ATOM   2084  C CG2  . VAL A 1 183 ? -20.859 26.695  12.006 1.00 14.01 ?  149  VAL A CG2  1 
ATOM   2085  H H    . VAL A 1 183 ? -21.694 25.455  9.700  1.00 15.20 ?  149  VAL A H    1 
ATOM   2086  H HA   . VAL A 1 183 ? -19.223 25.142  10.605 1.00 15.10 ?  149  VAL A HA   1 
ATOM   2087  H HB   . VAL A 1 183 ? -21.687 24.872  11.974 1.00 13.91 ?  149  VAL A HB   1 
ATOM   2088  H HG11 . VAL A 1 183 ? -20.408 25.035  13.958 1.00 15.40 ?  149  VAL A HG11 1 
ATOM   2089  H HG12 . VAL A 1 183 ? -20.108 23.697  13.157 1.00 15.40 ?  149  VAL A HG12 1 
ATOM   2090  H HG13 . VAL A 1 183 ? -19.092 24.915  13.077 1.00 15.40 ?  149  VAL A HG13 1 
ATOM   2091  H HG21 . VAL A 1 183 ? -21.209 26.959  12.870 1.00 16.81 ?  149  VAL A HG21 1 
ATOM   2092  H HG22 . VAL A 1 183 ? -19.970 27.064  11.882 1.00 16.81 ?  149  VAL A HG22 1 
ATOM   2093  H HG23 . VAL A 1 183 ? -21.448 27.007  11.301 1.00 16.81 ?  149  VAL A HG23 1 
ATOM   2094  N N    . GLN A 1 184 ? -20.989 22.508  10.304 1.00 11.90 ?  150  GLN A N    1 
ATOM   2095  C CA   . GLN A 1 184 ? -20.840 21.071  10.143 1.00 12.25 ?  150  GLN A CA   1 
ATOM   2096  C C    . GLN A 1 184 ? -19.786 20.740  9.101  1.00 12.60 ?  150  GLN A C    1 
ATOM   2097  O O    . GLN A 1 184 ? -18.920 19.866  9.320  1.00 13.49 ?  150  GLN A O    1 
ATOM   2098  C CB   . GLN A 1 184 ? -22.176 20.460  9.702  1.00 12.68 ?  150  GLN A CB   1 
ATOM   2099  C CG   . GLN A 1 184 ? -23.284 20.583  10.712 1.00 11.70 ?  150  GLN A CG   1 
ATOM   2100  C CD   . GLN A 1 184 ? -24.631 20.149  10.170 1.00 12.33 ?  150  GLN A CD   1 
ATOM   2101  O OE1  . GLN A 1 184 ? -24.686 19.379  9.203  1.00 14.06 ?  150  GLN A OE1  1 
ATOM   2102  N NE2  . GLN A 1 184 ? -25.702 20.642  10.758 1.00 14.48 ?  150  GLN A NE2  1 
ATOM   2103  H H    . GLN A 1 184 ? -21.785 22.811  10.187 1.00 14.28 ?  150  GLN A H    1 
ATOM   2104  H HA   . GLN A 1 184 ? -20.573 20.697  10.997 1.00 14.70 ?  150  GLN A HA   1 
ATOM   2105  H HB2  . GLN A 1 184 ? -22.467 20.906  8.892  1.00 15.22 ?  150  GLN A HB2  1 
ATOM   2106  H HB3  . GLN A 1 184 ? -22.041 19.515  9.530  1.00 15.22 ?  150  GLN A HB3  1 
ATOM   2107  H HG2  . GLN A 1 184 ? -23.076 20.026  11.478 1.00 14.04 ?  150  GLN A HG2  1 
ATOM   2108  H HG3  . GLN A 1 184 ? -23.358 21.511  10.987 1.00 14.04 ?  150  GLN A HG3  1 
ATOM   2109  H HE21 . GLN A 1 184 ? -25.618 21.186  11.419 1.00 17.37 ?  150  GLN A HE21 1 
ATOM   2110  H HE22 . GLN A 1 184 ? -26.485 20.421  10.480 1.00 17.37 ?  150  GLN A HE22 1 
ATOM   2111  N N    . GLU A 1 185 ? -19.833 21.417  7.957  1.00 13.01 ?  151  GLU A N    1 
ATOM   2112  C CA   . GLU A 1 185 ? -18.889 21.113  6.891  1.00 12.18 ?  151  GLU A CA   1 
ATOM   2113  C C    . GLU A 1 185 ? -17.459 21.463  7.290  1.00 12.27 ?  151  GLU A C    1 
ATOM   2114  O O    . GLU A 1 185 ? -16.531 20.689  6.993  1.00 13.09 ?  151  GLU A O    1 
ATOM   2115  C CB   . GLU A 1 185 ? -19.313 21.773  5.572  1.00 13.22 ?  151  GLU A CB   1 
ATOM   2116  C CG   . GLU A 1 185 ? -20.670 21.254  5.063  1.00 13.99 ?  151  GLU A CG   1 
ATOM   2117  C CD   . GLU A 1 185 ? -20.746 19.777  4.794  1.00 14.86 ?  151  GLU A CD   1 
ATOM   2118  O OE1  . GLU A 1 185 ? -19.722 19.142  4.464  1.00 15.53 ?  151  GLU A OE1  1 
ATOM   2119  O OE2  . GLU A 1 185 ? -21.870 19.229  4.847  1.00 16.95 ?  151  GLU A OE2  1 
ATOM   2120  H H    . GLU A 1 185 ? -20.391 22.045  7.777  1.00 15.61 ?  151  GLU A H    1 
ATOM   2121  H HA   . GLU A 1 185 ? -18.905 20.157  6.725  1.00 14.62 ?  151  GLU A HA   1 
ATOM   2122  H HB2  . GLU A 1 185 ? -19.388 22.730  5.707  1.00 15.86 ?  151  GLU A HB2  1 
ATOM   2123  H HB3  . GLU A 1 185 ? -18.645 21.585  4.894  1.00 15.86 ?  151  GLU A HB3  1 
ATOM   2124  H HG2  . GLU A 1 185 ? -21.344 21.459  5.730  1.00 16.79 ?  151  GLU A HG2  1 
ATOM   2125  H HG3  . GLU A 1 185 ? -20.877 21.709  4.231  1.00 16.79 ?  151  GLU A HG3  1 
ATOM   2126  N N    . TYR A 1 186 ? -17.262 22.602  7.939  1.00 12.04 ?  152  TYR A N    1 
ATOM   2127  C CA   . TYR A 1 186 ? -15.936 22.954  8.427  1.00 11.80 ?  152  TYR A CA   1 
ATOM   2128  C C    . TYR A 1 186 ? -15.419 21.896  9.381  1.00 12.10 ?  152  TYR A C    1 
ATOM   2129  O O    . TYR A 1 186 ? -14.274 21.431  9.264  1.00 12.64 ?  152  TYR A O    1 
ATOM   2130  C CB   . TYR A 1 186 ? -15.958 24.340  9.114  1.00 12.93 ?  152  TYR A CB   1 
ATOM   2131  C CG   . TYR A 1 186 ? -14.639 24.587  9.780  1.00 12.74 ?  152  TYR A CG   1 
ATOM   2132  C CD1  . TYR A 1 186 ? -13.543 25.027  9.045  1.00 12.45 ?  152  TYR A CD1  1 
ATOM   2133  C CD2  . TYR A 1 186 ? -14.445 24.301  11.141 1.00 11.44 ?  152  TYR A CD2  1 
ATOM   2134  C CE1  . TYR A 1 186 ? -12.298 25.186  9.633  1.00 13.67 ?  152  TYR A CE1  1 
ATOM   2135  C CE2  . TYR A 1 186 ? -13.172 24.461  11.733 1.00 11.99 ?  152  TYR A CE2  1 
ATOM   2136  C CZ   . TYR A 1 186 ? -12.128 24.884  10.970 1.00 11.33 ?  152  TYR A CZ   1 
ATOM   2137  O OH   . TYR A 1 186 ? -10.854 25.012  11.522 1.00 12.76 ?  152  TYR A OH   1 
ATOM   2138  H H    . TYR A 1 186 ? -17.872 23.184  8.108  1.00 14.44 ?  152  TYR A H    1 
ATOM   2139  H HA   . TYR A 1 186 ? -15.332 23.012  7.671  1.00 14.15 ?  152  TYR A HA   1 
ATOM   2140  H HB2  . TYR A 1 186 ? -16.110 25.032  8.452  1.00 15.51 ?  152  TYR A HB2  1 
ATOM   2141  H HB3  . TYR A 1 186 ? -16.658 24.363  9.785  1.00 15.51 ?  152  TYR A HB3  1 
ATOM   2142  H HD1  . TYR A 1 186 ? -13.648 25.218  8.141  1.00 14.94 ?  152  TYR A HD1  1 
ATOM   2143  H HD2  . TYR A 1 186 ? -15.160 24.005  11.656 1.00 13.73 ?  152  TYR A HD2  1 
ATOM   2144  H HE1  . TYR A 1 186 ? -11.580 25.495  9.129  1.00 16.40 ?  152  TYR A HE1  1 
ATOM   2145  H HE2  . TYR A 1 186 ? -13.048 24.278  12.637 1.00 14.38 ?  152  TYR A HE2  1 
ATOM   2146  H HH   . TYR A 1 186 ? -10.831 24.650  12.279 1.00 15.32 ?  152  TYR A HH   1 
ATOM   2147  N N    . TRP A 1 187 ? -16.243 21.497  10.348 1.00 11.81 ?  153  TRP A N    1 
ATOM   2148  C CA   . TRP A 1 187 ? -15.779 20.616  11.403 1.00 11.26 ?  153  TRP A CA   1 
ATOM   2149  C C    . TRP A 1 187 ? -15.466 19.250  10.824 1.00 11.29 ?  153  TRP A C    1 
ATOM   2150  O O    . TRP A 1 187 ? -14.417 18.675  11.104 1.00 11.99 ?  153  TRP A O    1 
ATOM   2151  C CB   . TRP A 1 187 ? -16.874 20.545  12.477 1.00 12.54 ?  153  TRP A CB   1 
ATOM   2152  C CG   . TRP A 1 187 ? -16.464 19.815  13.728 1.00 11.30 ?  153  TRP A CG   1 
ATOM   2153  C CD1  . TRP A 1 187 ? -15.957 20.361  14.876 1.00 11.74 ?  153  TRP A CD1  1 
ATOM   2154  C CD2  . TRP A 1 187 ? -16.520 18.399  13.947 1.00 11.11 ?  153  TRP A CD2  1 
ATOM   2155  N NE1  . TRP A 1 187 ? -15.700 19.361  15.783 1.00 11.93 ?  153  TRP A NE1  1 
ATOM   2156  C CE2  . TRP A 1 187 ? -16.037 18.151  15.250 1.00 11.68 ?  153  TRP A CE2  1 
ATOM   2157  C CE3  . TRP A 1 187 ? -16.971 17.305  13.188 1.00 12.11 ?  153  TRP A CE3  1 
ATOM   2158  C CZ2  . TRP A 1 187 ? -16.002 16.881  15.825 1.00 11.45 ?  153  TRP A CZ2  1 
ATOM   2159  C CZ3  . TRP A 1 187 ? -16.901 16.031  13.743 1.00 12.17 ?  153  TRP A CZ3  1 
ATOM   2160  C CH2  . TRP A 1 187 ? -16.407 15.831  15.048 1.00 11.81 ?  153  TRP A CH2  1 
ATOM   2161  H H    . TRP A 1 187 ? -17.070 21.724  10.412 1.00 14.17 ?  153  TRP A H    1 
ATOM   2162  H HA   . TRP A 1 187 ? -14.969 20.951  11.819 1.00 13.51 ?  153  TRP A HA   1 
ATOM   2163  H HB2  . TRP A 1 187 ? -17.119 21.449  12.730 1.00 15.04 ?  153  TRP A HB2  1 
ATOM   2164  H HB3  . TRP A 1 187 ? -17.643 20.085  12.106 1.00 15.04 ?  153  TRP A HB3  1 
ATOM   2165  H HD1  . TRP A 1 187 ? -15.808 21.268  15.019 1.00 14.09 ?  153  TRP A HD1  1 
ATOM   2166  H HE1  . TRP A 1 187 ? -15.375 19.481  16.570 1.00 14.31 ?  153  TRP A HE1  1 
ATOM   2167  H HE3  . TRP A 1 187 ? -17.311 17.430  12.331 1.00 14.54 ?  153  TRP A HE3  1 
ATOM   2168  H HZ2  . TRP A 1 187 ? -15.716 16.754  16.700 1.00 13.74 ?  153  TRP A HZ2  1 
ATOM   2169  H HZ3  . TRP A 1 187 ? -17.185 15.299  13.245 1.00 14.61 ?  153  TRP A HZ3  1 
ATOM   2170  H HH2  . TRP A 1 187 ? -16.356 14.967  15.387 1.00 14.17 ?  153  TRP A HH2  1 
ATOM   2171  N N    . LEU A 1 188 ? -16.372 18.697  10.016 1.00 11.98 ?  154  LEU A N    1 
ATOM   2172  C CA   . LEU A 1 188 ? -16.143 17.381  9.419  1.00 11.97 ?  154  LEU A CA   1 
ATOM   2173  C C    . LEU A 1 188 ? -14.884 17.382  8.566  1.00 11.55 ?  154  LEU A C    1 
ATOM   2174  O O    . LEU A 1 188 ? -14.088 16.438  8.648  1.00 12.54 ?  154  LEU A O    1 
ATOM   2175  C CB   . LEU A 1 188 ? -17.375 16.967  8.587  1.00 12.88 ?  154  LEU A CB   1 
ATOM   2176  C CG   . LEU A 1 188 ? -18.602 16.598  9.403  1.00 12.73 ?  154  LEU A CG   1 
ATOM   2177  C CD1  . LEU A 1 188 ? -19.808 16.539  8.500  1.00 12.85 ?  154  LEU A CD1  1 
ATOM   2178  C CD2  . LEU A 1 188 ? -18.373 15.290  10.113 1.00 13.39 ?  154  LEU A CD2  1 
ATOM   2179  H H    . LEU A 1 188 ? -17.121 19.060  9.799  1.00 14.38 ?  154  LEU A H    1 
ATOM   2180  H HA   . LEU A 1 188 ? -16.023 16.725  10.124 1.00 14.37 ?  154  LEU A HA   1 
ATOM   2181  H HB2  . LEU A 1 188 ? -17.619 17.709  8.011  1.00 15.45 ?  154  LEU A HB2  1 
ATOM   2182  H HB3  . LEU A 1 188 ? -17.137 16.195  8.050  1.00 15.45 ?  154  LEU A HB3  1 
ATOM   2183  H HG   . LEU A 1 188 ? -18.773 17.270  10.082 1.00 15.28 ?  154  LEU A HG   1 
ATOM   2184  H HD11 . LEU A 1 188 ? -20.062 15.612  8.374  1.00 15.42 ?  154  LEU A HD11 1 
ATOM   2185  H HD12 . LEU A 1 188 ? -20.536 17.029  8.913  1.00 15.42 ?  154  LEU A HD12 1 
ATOM   2186  H HD13 . LEU A 1 188 ? -19.582 16.940  7.646  1.00 15.42 ?  154  LEU A HD13 1 
ATOM   2187  H HD21 . LEU A 1 188 ? -19.184 15.038  10.581 1.00 16.06 ?  154  LEU A HD21 1 
ATOM   2188  H HD22 . LEU A 1 188 ? -18.144 14.611  9.459  1.00 16.06 ?  154  LEU A HD22 1 
ATOM   2189  H HD23 . LEU A 1 188 ? -17.646 15.397  10.746 1.00 16.06 ?  154  LEU A HD23 1 
ATOM   2190  N N    . LYS A 1 189 ? -14.718 18.407  7.741  1.00 13.04 ?  155  LYS A N    1 
ATOM   2191  C CA   . LYS A 1 189 ? -13.523 18.489  6.905  1.00 13.81 ?  155  LYS A CA   1 
ATOM   2192  C C    . LYS A 1 189 ? -12.273 18.566  7.771  1.00 13.52 ?  155  LYS A C    1 
ATOM   2193  O O    . LYS A 1 189 ? -11.241 17.968  7.434  1.00 12.95 ?  155  LYS A O    1 
ATOM   2194  C CB   . LYS A 1 189 ? -13.617 19.650  5.921  1.00 14.75 ?  155  LYS A CB   1 
ATOM   2195  C CG   . LYS A 1 189 ? -12.338 19.909  5.150  1.00 16.16 ?  155  LYS A CG   1 
ATOM   2196  C CD   . LYS A 1 189 ? -12.585 20.944  4.019  1.00 18.02 ?  155  LYS A CD   1 
ATOM   2197  C CE   . LYS A 1 189 ? -11.296 21.590  3.578  1.00 21.88 ?  155  LYS A CE   1 
ATOM   2198  N NZ   . LYS A 1 189 ? -10.431 20.595  2.906  1.00 26.03 ?  155  LYS A NZ   1 
ATOM   2199  H H    . LYS A 1 189 ? -15.271 19.059  7.646  1.00 15.65 ?  155  LYS A H    1 
ATOM   2200  H HA   . LYS A 1 189 ? -13.460 17.688  6.361  1.00 16.57 ?  155  LYS A HA   1 
ATOM   2201  H HB2  . LYS A 1 189 ? -14.316 19.456  5.277  1.00 17.70 ?  155  LYS A HB2  1 
ATOM   2202  H HB3  . LYS A 1 189 ? -13.833 20.457  6.413  1.00 17.70 ?  155  LYS A HB3  1 
ATOM   2203  H HG2  . LYS A 1 189 ? -11.663 20.262  5.750  1.00 19.40 ?  155  LYS A HG2  1 
ATOM   2204  H HG3  . LYS A 1 189 ? -12.027 19.082  4.750  1.00 19.40 ?  155  LYS A HG3  1 
ATOM   2205  H HD2  . LYS A 1 189 ? -12.980 20.497  3.254  1.00 21.63 ?  155  LYS A HD2  1 
ATOM   2206  H HD3  . LYS A 1 189 ? -13.180 21.638  4.341  1.00 21.63 ?  155  LYS A HD3  1 
ATOM   2207  H HE2  . LYS A 1 189 ? -11.488 22.307  2.953  1.00 26.26 ?  155  LYS A HE2  1 
ATOM   2208  H HE3  . LYS A 1 189 ? -10.826 21.940  4.350  1.00 26.26 ?  155  LYS A HE3  1 
ATOM   2209  H HZ1  . LYS A 1 189 ? -10.206 19.952  3.479  1.00 31.23 ?  155  LYS A HZ1  1 
ATOM   2210  H HZ2  . LYS A 1 189 ? -10.863 20.231  2.218  1.00 31.23 ?  155  LYS A HZ2  1 
ATOM   2211  H HZ3  . LYS A 1 189 ? -9.691  20.988  2.607  1.00 31.23 ?  155  LYS A HZ3  1 
ATOM   2212  N N    . SER A 1 190 ? -12.310 19.310  8.895  1.00 12.68 ?  156  SER A N    1 
ATOM   2213  C CA   . SER A 1 190 ? -11.098 19.406  9.720  1.00 11.93 ?  156  SER A CA   1 
ATOM   2214  C C    . SER A 1 190 ? -10.691 18.036  10.231 1.00 12.38 ?  156  SER A C    1 
ATOM   2215  O O    . SER A 1 190 ? -9.496  17.721  10.305 1.00 12.33 ?  156  SER A O    1 
ATOM   2216  C CB   . SER A 1 190 ? -11.337 20.401  10.851 1.00 12.86 ?  156  SER A CB   1 
ATOM   2217  O OG   . SER A 1 190 ? -12.152 19.919  11.923 1.00 12.94 ?  156  SER A OG   1 
ATOM   2218  H H    . SER A 1 190 ? -12.993 19.746  9.185  1.00 15.21 ?  156  SER A H    1 
ATOM   2219  H HA   . SER A 1 190 ? -10.356 19.744  9.195  1.00 14.31 ?  156  SER A HA   1 
ATOM   2220  H HB2  . SER A 1 190 ? -10.474 20.647  11.220 1.00 15.43 ?  156  SER A HB2  1 
ATOM   2221  H HB3  . SER A 1 190 ? -11.771 21.183  10.474 1.00 15.43 ?  156  SER A HB3  1 
ATOM   2222  H HG   . SER A 1 190 ? -12.933 19.774  11.648 1.00 15.53 ?  156  SER A HG   1 
ATOM   2223  N N    . VAL A 1 191 ? -11.655 17.214  10.625 1.00 11.31 ?  157  VAL A N    1 
ATOM   2224  C CA   . VAL A 1 191 ? -11.349 15.895  11.160 1.00 12.12 ?  157  VAL A CA   1 
ATOM   2225  C C    . VAL A 1 191 ? -10.867 14.979  10.044 1.00 12.12 ?  157  VAL A C    1 
ATOM   2226  O O    . VAL A 1 191 ? -9.829  14.338  10.147 1.00 12.98 ?  157  VAL A O    1 
ATOM   2227  C CB   . VAL A 1 191 ? -12.585 15.304  11.883 1.00 12.05 ?  157  VAL A CB   1 
ATOM   2228  C CG1  . VAL A 1 191 ? -12.349 13.831  12.253 1.00 11.72 ?  157  VAL A CG1  1 
ATOM   2229  C CG2  . VAL A 1 191 ? -12.970 16.108  13.116 1.00 12.71 ?  157  VAL A CG2  1 
ATOM   2230  H H    . VAL A 1 191 ? -12.495 17.395  10.593 1.00 13.58 ?  157  VAL A H    1 
ATOM   2231  H HA   . VAL A 1 191 ? -10.636 15.982  11.812 1.00 14.55 ?  157  VAL A HA   1 
ATOM   2232  H HB   . VAL A 1 191 ? -13.332 15.353  11.266 1.00 14.46 ?  157  VAL A HB   1 
ATOM   2233  H HG11 . VAL A 1 191 ? -13.104 13.510  12.769 1.00 14.06 ?  157  VAL A HG11 1 
ATOM   2234  H HG12 . VAL A 1 191 ? -12.259 13.312  11.438 1.00 14.06 ?  157  VAL A HG12 1 
ATOM   2235  H HG13 . VAL A 1 191 ? -11.536 13.764  12.779 1.00 14.06 ?  157  VAL A HG13 1 
ATOM   2236  H HG21 . VAL A 1 191 ? -13.809 15.769  13.466 1.00 15.25 ?  157  VAL A HG21 1 
ATOM   2237  H HG22 . VAL A 1 191 ? -12.272 16.016  13.784 1.00 15.25 ?  157  VAL A HG22 1 
ATOM   2238  H HG23 . VAL A 1 191 ? -13.068 17.041  12.867 1.00 15.25 ?  157  VAL A HG23 1 
ATOM   2239  N N    . GLU A 1 192 ? -11.621 14.939  8.943  1.00 12.64 ?  158  GLU A N    1 
ATOM   2240  C CA   . GLU A 1 192 ? -11.253 14.073  7.811  1.00 12.71 ?  158  GLU A CA   1 
ATOM   2241  C C    . GLU A 1 192 ? -9.876  14.424  7.262  1.00 12.10 ?  158  GLU A C    1 
ATOM   2242  O O    . GLU A 1 192 ? -9.074  13.520  6.996  1.00 13.97 ?  158  GLU A O    1 
ATOM   2243  C CB   . GLU A 1 192 ? -12.337 14.157  6.719  1.00 13.63 ?  158  GLU A CB   1 
ATOM   2244  C CG   . GLU A 1 192 ? -13.667 13.560  7.199  1.00 15.22 ?  158  GLU A CG   1 
ATOM   2245  C CD   . GLU A 1 192 ? -14.870 13.843  6.308  1.00 14.82 ?  158  GLU A CD   1 
ATOM   2246  O OE1  . GLU A 1 192 ? -14.737 14.646  5.360  1.00 17.95 ?  158  GLU A OE1  1 
ATOM   2247  O OE2  . GLU A 1 192 ? -15.940 13.280  6.605  1.00 17.47 ?  158  GLU A OE2  1 
ATOM   2248  H H    . GLU A 1 192 ? -12.341 15.396  8.823  1.00 15.16 ?  158  GLU A H    1 
ATOM   2249  H HA   . GLU A 1 192 ? -11.211 13.153  8.115  1.00 15.25 ?  158  GLU A HA   1 
ATOM   2250  H HB2  . GLU A 1 192 ? -12.486 15.087  6.486  1.00 16.36 ?  158  GLU A HB2  1 
ATOM   2251  H HB3  . GLU A 1 192 ? -12.044 13.662  5.938  1.00 16.36 ?  158  GLU A HB3  1 
ATOM   2252  H HG2  . GLU A 1 192 ? -13.568 12.596  7.252  1.00 18.26 ?  158  GLU A HG2  1 
ATOM   2253  H HG3  . GLU A 1 192 ? -13.866 13.922  8.076  1.00 18.26 ?  158  GLU A HG3  1 
ATOM   2254  N N    . ASP A 1 193 ? -9.565  15.709  7.144  1.00 12.43 ?  159  ASP A N    1 
ATOM   2255  C CA   . ASP A 1 193 ? -8.273  16.104  6.592  1.00 13.54 ?  159  ASP A CA   1 
ATOM   2256  C C    . ASP A 1 193 ? -7.139  15.652  7.501  1.00 14.47 ?  159  ASP A C    1 
ATOM   2257  O O    . ASP A 1 193 ? -6.100  15.202  7.027  1.00 15.14 ?  159  ASP A O    1 
ATOM   2258  C CB   . ASP A 1 193 ? -8.204  17.616  6.368  1.00 13.40 ?  159  ASP A CB   1 
ATOM   2259  C CG   . ASP A 1 193 ? -8.976  18.098  5.148  1.00 14.27 ?  159  ASP A CG   1 
ATOM   2260  O OD1  . ASP A 1 193 ? -9.458  17.276  4.372  1.00 19.53 ?  159  ASP A OD1  1 
ATOM   2261  O OD2  . ASP A 1 193 ? -9.069  19.337  4.993  1.00 17.83 ?  159  ASP A OD2  1 
ATOM   2262  H H    . ASP A 1 193 ? -10.075 16.363  7.372  1.00 14.91 ?  159  ASP A H    1 
ATOM   2263  H HA   . ASP A 1 193 ? -8.172  15.681  5.725  1.00 16.25 ?  159  ASP A HA   1 
ATOM   2264  H HB2  . ASP A 1 193 ? -8.573  18.063  7.145  1.00 16.08 ?  159  ASP A HB2  1 
ATOM   2265  H HB3  . ASP A 1 193 ? -7.275  17.870  6.248  1.00 16.08 ?  159  ASP A HB3  1 
ATOM   2266  N N    . MET A 1 194 ? -7.287  15.803  8.827  1.00 11.64 ?  160  MET A N    1 
ATOM   2267  C CA   . MET A 1 194 ? -6.232  15.349  9.734  1.00 12.17 ?  160  MET A CA   1 
ATOM   2268  C C    . MET A 1 194 ? -6.088  13.840  9.725  1.00 13.28 ?  160  MET A C    1 
ATOM   2269  O O    . MET A 1 194 ? -4.972  13.310  9.702  1.00 12.83 ?  160  MET A O    1 
ATOM   2270  C CB   . MET A 1 194 ? -6.533  15.847  11.150 1.00 12.19 ?  160  MET A CB   1 
ATOM   2271  C CG   . MET A 1 194 ? -5.391  15.689  12.123 1.00 12.80 ?  160  MET A CG   1 
ATOM   2272  S SD   . MET A 1 194 ? -3.748  16.254  11.758 1.00 13.80 ?  160  MET A SD   1 
ATOM   2273  C CE   . MET A 1 194 ? -4.015  17.969  12.333 1.00 16.02 ?  160  MET A CE   1 
ATOM   2274  H H    . MET A 1 194 ? -7.970  16.156  9.212  1.00 13.97 ?  160  MET A H    1 
ATOM   2275  H HA   . MET A 1 194 ? -5.391  15.732  9.442  1.00 14.61 ?  160  MET A HA   1 
ATOM   2276  H HB2  . MET A 1 194 ? -6.751  16.791  11.105 1.00 14.62 ?  160  MET A HB2  1 
ATOM   2277  H HB3  . MET A 1 194 ? -7.288  15.348  11.500 1.00 14.62 ?  160  MET A HB3  1 
ATOM   2278  H HG2  . MET A 1 194 ? -5.649  16.153  12.934 1.00 15.35 ?  160  MET A HG2  1 
ATOM   2279  H HG3  . MET A 1 194 ? -5.304  14.738  12.298 1.00 15.35 ?  160  MET A HG3  1 
ATOM   2280  H HE1  . MET A 1 194 ? -3.200  18.478  12.198 1.00 19.23 ?  160  MET A HE1  1 
ATOM   2281  H HE2  . MET A 1 194 ? -4.740  18.364  11.823 1.00 19.23 ?  160  MET A HE2  1 
ATOM   2282  H HE3  . MET A 1 194 ? -4.244  17.955  13.275 1.00 19.23 ?  160  MET A HE3  1 
ATOM   2283  N N    . VAL A 1 195 ? -7.201  13.125  9.759  1.00 11.68 ?  161  VAL A N    1 
ATOM   2284  C CA   . VAL A 1 195 ? -7.123  11.677  9.791  1.00 13.16 ?  161  VAL A CA   1 
ATOM   2285  C C    . VAL A 1 195 ? -6.528  11.142  8.495  1.00 12.74 ?  161  VAL A C    1 
ATOM   2286  O O    . VAL A 1 195 ? -5.885  10.080  8.515  1.00 13.13 ?  161  VAL A O    1 
ATOM   2287  C CB   . VAL A 1 195 ? -8.484  11.049  10.156 1.00 12.40 ?  161  VAL A CB   1 
ATOM   2288  C CG1  . VAL A 1 195 ? -8.419  9.557   10.066 1.00 14.03 ?  161  VAL A CG1  1 
ATOM   2289  C CG2  . VAL A 1 195 ? -8.859  11.488  11.566 1.00 11.94 ?  161  VAL A CG2  1 
ATOM   2290  H H    . VAL A 1 195 ? -7.998  13.448  9.764  1.00 14.01 ?  161  VAL A H    1 
ATOM   2291  H HA   . VAL A 1 195 ? -6.518  11.417  10.504 1.00 15.79 ?  161  VAL A HA   1 
ATOM   2292  H HB   . VAL A 1 195 ? -9.164  11.346  9.532  1.00 14.88 ?  161  VAL A HB   1 
ATOM   2293  H HG11 . VAL A 1 195 ? -9.237  9.183   10.430 1.00 16.83 ?  161  VAL A HG11 1 
ATOM   2294  H HG12 . VAL A 1 195 ? -8.324  9.301   9.135  1.00 16.83 ?  161  VAL A HG12 1 
ATOM   2295  H HG13 . VAL A 1 195 ? -7.656  9.243   10.576 1.00 16.83 ?  161  VAL A HG13 1 
ATOM   2296  H HG21 . VAL A 1 195 ? -9.754  11.172  11.767 1.00 14.33 ?  161  VAL A HG21 1 
ATOM   2297  H HG22 . VAL A 1 195 ? -8.225  11.108  12.194 1.00 14.33 ?  161  VAL A HG22 1 
ATOM   2298  H HG23 . VAL A 1 195 ? -8.831  12.456  11.613 1.00 14.33 ?  161  VAL A HG23 1 
ATOM   2299  N N    . ALA A 1 196 ? -6.706  11.840  7.373  1.00 13.44 ?  162  ALA A N    1 
ATOM   2300  C CA   . ALA A 1 196 ? -6.182  11.358  6.087  1.00 12.22 ?  162  ALA A CA   1 
ATOM   2301  C C    . ALA A 1 196 ? -4.670  11.428  6.030  1.00 15.10 ?  162  ALA A C    1 
ATOM   2302  O O    . ALA A 1 196 ? -4.079  10.790  5.140  1.00 16.43 ?  162  ALA A O    1 
ATOM   2303  C CB   . ALA A 1 196 ? -6.753  12.171  4.953  1.00 14.34 ?  162  ALA A CB   1 
ATOM   2304  H H    . ALA A 1 196 ? -7.124  12.591  7.326  1.00 16.13 ?  162  ALA A H    1 
ATOM   2305  H HA   . ALA A 1 196 ? -6.459  10.436  5.964  1.00 14.67 ?  162  ALA A HA   1 
ATOM   2306  H HB1  . ALA A 1 196 ? -6.413  11.825  4.113  1.00 17.21 ?  162  ALA A HB1  1 
ATOM   2307  H HB2  . ALA A 1 196 ? -7.721  12.103  4.971  1.00 17.21 ?  162  ALA A HB2  1 
ATOM   2308  H HB3  . ALA A 1 196 ? -6.485  13.097  5.062  1.00 17.21 ?  162  ALA A HB3  1 
ATOM   2309  N N    . THR A 1 197 ? -4.012  12.153  6.943  1.00 12.48 ?  163  THR A N    1 
ATOM   2310  C CA   . THR A 1 197 ? -2.546  12.262  6.904  1.00 13.70 ?  163  THR A CA   1 
ATOM   2311  C C    . THR A 1 197 ? -1.902  10.945  7.330  1.00 13.76 ?  163  THR A C    1 
ATOM   2312  O O    . THR A 1 197 ? -2.538  10.080  7.925  1.00 13.21 ?  163  THR A O    1 
ATOM   2313  C CB   . THR A 1 197 ? -2.025  13.454  7.729  1.00 12.81 ?  163  THR A CB   1 
ATOM   2314  O OG1  . THR A 1 197 ? -2.274  13.208  9.126  1.00 14.28 ?  163  THR A OG1  1 
ATOM   2315  C CG2  . THR A 1 197 ? -2.671  14.756  7.313  1.00 15.26 ?  163  THR A CG2  1 
ATOM   2316  H H    . THR A 1 197 ? -4.384  12.585  7.587  1.00 14.97 ?  163  THR A H    1 
ATOM   2317  H HA   . THR A 1 197 ? -2.268  12.442  5.992  1.00 16.44 ?  163  THR A HA   1 
ATOM   2318  H HB   . THR A 1 197 ? -1.072  13.550  7.576  1.00 15.37 ?  163  THR A HB   1 
ATOM   2319  H HG1  . THR A 1 197 ? -3.085  13.025  9.246  1.00 17.14 ?  163  THR A HG1  1 
ATOM   2320  H HG21 . THR A 1 197 ? -2.404  15.467  7.916  1.00 18.31 ?  163  THR A HG21 1 
ATOM   2321  H HG22 . THR A 1 197 ? -2.398  14.989  6.412  1.00 18.31 ?  163  THR A HG22 1 
ATOM   2322  H HG23 . THR A 1 197 ? -3.637  14.670  7.337  1.00 18.31 ?  163  THR A HG23 1 
ATOM   2323  N N    . PRO A 1 198 ? -0.635  10.714  6.987  1.00 14.64 ?  164  PRO A N    1 
ATOM   2324  C CA   . PRO A 1 198 ? -0.130  9.333   7.051  1.00 15.96 ?  164  PRO A CA   1 
ATOM   2325  C C    . PRO A 1 198 ? 0.043   8.764   8.438  1.00 15.51 ?  164  PRO A C    1 
ATOM   2326  O O    . PRO A 1 198 ? 0.052   7.527   8.601  1.00 17.70 ?  164  PRO A O    1 
ATOM   2327  C CB   . PRO A 1 198 ? 1.209   9.394   6.288  1.00 19.06 ?  164  PRO A CB   1 
ATOM   2328  C CG   . PRO A 1 198 ? 1.516   10.759  6.115  1.00 23.00 ?  164  PRO A CG   1 
ATOM   2329  C CD   . PRO A 1 198 ? 0.259   11.588  6.220  1.00 17.00 ?  164  PRO A CD   1 
ATOM   2330  H HA   . PRO A 1 198 ? -0.753  8.763   6.573  1.00 19.15 ?  164  PRO A HA   1 
ATOM   2331  H HB2  . PRO A 1 198 ? 1.898   8.953   6.809  1.00 22.88 ?  164  PRO A HB2  1 
ATOM   2332  H HB3  . PRO A 1 198 ? 1.111   8.955   5.428  1.00 22.88 ?  164  PRO A HB3  1 
ATOM   2333  H HG2  . PRO A 1 198 ? 2.143   11.025  6.805  1.00 27.60 ?  164  PRO A HG2  1 
ATOM   2334  H HG3  . PRO A 1 198 ? 1.915   10.878  5.239  1.00 27.60 ?  164  PRO A HG3  1 
ATOM   2335  H HD2  . PRO A 1 198 ? 0.427   12.417  6.696  1.00 20.40 ?  164  PRO A HD2  1 
ATOM   2336  H HD3  . PRO A 1 198 ? -0.108  11.778  5.343  1.00 20.40 ?  164  PRO A HD3  1 
ATOM   2337  N N    . ASN A 1 199 ? 0.249   9.600   9.445  1.00 13.54 ?  165  ASN A N    1 
ATOM   2338  C CA   . ASN A 1 199 ? 0.650   9.151   10.768 1.00 13.98 ?  165  ASN A CA   1 
ATOM   2339  C C    . ASN A 1 199 ? -0.491  9.217   11.777 1.00 13.85 ?  165  ASN A C    1 
ATOM   2340  O O    . ASN A 1 199 ? -0.276  8.971   12.963 1.00 14.27 ?  165  ASN A O    1 
ATOM   2341  C CB   . ASN A 1 199 ? 1.867   9.953   11.248 1.00 13.76 ?  165  ASN A CB   1 
ATOM   2342  C CG   . ASN A 1 199 ? 3.029   9.808   10.286 1.00 13.96 ?  165  ASN A CG   1 
ATOM   2343  O OD1  . ASN A 1 199 ? 3.423   8.679   10.017 1.00 17.49 ?  165  ASN A OD1  1 
ATOM   2344  N ND2  . ASN A 1 199 ? 3.495   10.890  9.721  1.00 14.63 ?  165  ASN A ND2  1 
ATOM   2345  H H    . ASN A 1 199 ? 0.160   10.454  9.385  1.00 16.25 ?  165  ASN A H    1 
ATOM   2346  H HA   . ASN A 1 199 ? 0.925   8.222   10.717 1.00 16.77 ?  165  ASN A HA   1 
ATOM   2347  H HB2  . ASN A 1 199 ? 1.632   10.892  11.306 1.00 16.51 ?  165  ASN A HB2  1 
ATOM   2348  H HB3  . ASN A 1 199 ? 2.146   9.626   12.118 1.00 16.51 ?  165  ASN A HB3  1 
ATOM   2349  H HD21 . ASN A 1 199 ? 4.154   10.838  9.171  1.00 17.55 ?  165  ASN A HD21 1 
ATOM   2350  H HD22 . ASN A 1 199 ? 3.143   11.654  9.899  1.00 17.55 ?  165  ASN A HD22 1 
ATOM   2351  N N    . ILE A 1 200 ? -1.693  9.535   11.324 1.00 12.69 ?  166  ILE A N    1 
ATOM   2352  C CA   . ILE A 1 200 ? -2.891  9.575   12.165 1.00 12.92 ?  166  ILE A CA   1 
ATOM   2353  C C    . ILE A 1 200 ? -3.812  8.440   11.751 1.00 12.41 ?  166  ILE A C    1 
ATOM   2354  O O    . ILE A 1 200 ? -4.129  8.281   10.577 1.00 12.67 ?  166  ILE A O    1 
ATOM   2355  C CB   . ILE A 1 200 ? -3.609  10.931  12.061 1.00 12.37 ?  166  ILE A CB   1 
ATOM   2356  C CG1  . ILE A 1 200 ? -2.706  12.102  12.510 1.00 14.33 ?  166  ILE A CG1  1 
ATOM   2357  C CG2  . ILE A 1 200 ? -4.914  10.895  12.841 1.00 12.03 ?  166  ILE A CG2  1 
ATOM   2358  C CD1  . ILE A 1 200 ? -2.395  12.114  13.983 1.00 17.19 ?  166  ILE A CD1  1 
ATOM   2359  H H    . ILE A 1 200 ? -1.851  9.740   10.504 1.00 15.23 ?  166  ILE A H    1 
ATOM   2360  H HA   . ILE A 1 200 ? -2.633  9.435   13.090 1.00 15.50 ?  166  ILE A HA   1 
ATOM   2361  H HB   . ILE A 1 200 ? -3.813  11.088  11.125 1.00 14.84 ?  166  ILE A HB   1 
ATOM   2362  H HG12 . ILE A 1 200 ? -1.863  12.044  12.033 1.00 17.20 ?  166  ILE A HG12 1 
ATOM   2363  H HG13 . ILE A 1 200 ? -3.152  12.936  12.297 1.00 17.20 ?  166  ILE A HG13 1 
ATOM   2364  H HG21 . ILE A 1 200 ? -5.321  11.776  12.817 1.00 14.43 ?  166  ILE A HG21 1 
ATOM   2365  H HG22 . ILE A 1 200 ? -5.508  10.245  12.434 1.00 14.43 ?  166  ILE A HG22 1 
ATOM   2366  H HG23 . ILE A 1 200 ? -4.726  10.643  13.759 1.00 14.43 ?  166  ILE A HG23 1 
ATOM   2367  H HD11 . ILE A 1 200 ? -1.764  12.828  14.167 1.00 20.62 ?  166  ILE A HD11 1 
ATOM   2368  H HD12 . ILE A 1 200 ? -3.216  12.263  14.478 1.00 20.62 ?  166  ILE A HD12 1 
ATOM   2369  H HD13 . ILE A 1 200 ? -2.009  11.259  14.232 1.00 20.62 ?  166  ILE A HD13 1 
ATOM   2370  N N    . ASP A 1 201 ? -4.253  7.653   12.720 1.00 11.88 ?  167  ASP A N    1 
ATOM   2371  C CA   . ASP A 1 201 ? -5.076  6.474   12.457 1.00 11.90 ?  167  ASP A CA   1 
ATOM   2372  C C    . ASP A 1 201 ? -6.551  6.698   12.695 1.00 11.53 ?  167  ASP A C    1 
ATOM   2373  O O    . ASP A 1 201 ? -7.366  5.876   12.269 1.00 12.78 ?  167  ASP A O    1 
ATOM   2374  C CB   . ASP A 1 201 ? -4.599  5.304   13.301 1.00 11.95 ?  167  ASP A CB   1 
ATOM   2375  C CG   . ASP A 1 201 ? -3.166  4.988   12.988 1.00 13.31 ?  167  ASP A CG   1 
ATOM   2376  O OD1  . ASP A 1 201 ? -2.890  4.634   11.796 1.00 14.38 ?  167  ASP A OD1  1 
ATOM   2377  O OD2  . ASP A 1 201 ? -2.295  5.088   13.867 1.00 13.74 ?  167  ASP A OD2  1 
ATOM   2378  H H    . ASP A 1 201 ? -4.089  7.780   13.554 1.00 14.26 ?  167  ASP A H    1 
ATOM   2379  H HA   . ASP A 1 201 ? -4.971  6.232   11.523 1.00 14.28 ?  167  ASP A HA   1 
ATOM   2380  H HB2  . ASP A 1 201 ? -4.668  5.532   14.241 1.00 14.34 ?  167  ASP A HB2  1 
ATOM   2381  H HB3  . ASP A 1 201 ? -5.139  4.522   13.108 1.00 14.34 ?  167  ASP A HB3  1 
ATOM   2382  N N    . GLY A 1 202 ? -6.930  7.773   13.369 1.00 11.21 ?  168  GLY A N    1 
ATOM   2383  C CA   . GLY A 1 202 ? -8.324  7.949   13.701 1.00 12.18 ?  168  GLY A CA   1 
ATOM   2384  C C    . GLY A 1 202 ? -8.485  9.171   14.570 1.00 11.71 ?  168  GLY A C    1 
ATOM   2385  O O    . GLY A 1 202 ? -7.602  10.019  14.664 1.00 11.94 ?  168  GLY A O    1 
ATOM   2386  H H    . GLY A 1 202 ? -6.407  8.400   13.639 1.00 13.45 ?  168  GLY A H    1 
ATOM   2387  H HA2  . GLY A 1 202 ? -8.847  8.064   12.892 1.00 14.62 ?  168  GLY A HA2  1 
ATOM   2388  H HA3  . GLY A 1 202 ? -8.652  7.173   14.182 1.00 14.62 ?  168  GLY A HA3  1 
ATOM   2389  N N    . THR A 1 203 ? -9.671  9.259   15.166 1.00 11.32 ?  169  THR A N    1 
ATOM   2390  C CA   . THR A 1 203 ? -10.040 10.434  15.941 1.00 10.65 ?  169  THR A CA   1 
ATOM   2391  C C    . THR A 1 203 ? -10.707 9.985   17.223 1.00 10.45 ?  169  THR A C    1 
ATOM   2392  O O    . THR A 1 203 ? -11.347 8.936   17.283 1.00 11.70 ?  169  THR A O    1 
ATOM   2393  C CB   . THR A 1 203 ? -10.949 11.364  15.105 1.00 11.45 ?  169  THR A CB   1 
ATOM   2394  O OG1  . THR A 1 203 ? -11.231 12.591  15.784 1.00 11.57 ?  169  THR A OG1  1 
ATOM   2395  C CG2  . THR A 1 203 ? -12.288 10.756  14.792 1.00 12.95 ?  169  THR A CG2  1 
ATOM   2396  H H    . THR A 1 203 ? -10.277 8.650   15.135 1.00 13.58 ?  169  THR A H    1 
ATOM   2397  H HA   . THR A 1 203 ? -9.260  10.947  16.202 1.00 12.78 ?  169  THR A HA   1 
ATOM   2398  H HB   . THR A 1 203 ? -10.456 11.522  14.284 1.00 13.74 ?  169  THR A HB   1 
ATOM   2399  H HG1  . THR A 1 203 ? -10.514 12.954  16.030 1.00 13.89 ?  169  THR A HG1  1 
ATOM   2400  H HG21 . THR A 1 203 ? -12.735 11.274  14.105 1.00 15.54 ?  169  THR A HG21 1 
ATOM   2401  H HG22 . THR A 1 203 ? -12.173 9.846   14.475 1.00 15.54 ?  169  THR A HG22 1 
ATOM   2402  H HG23 . THR A 1 203 ? -12.842 10.745  15.588 1.00 15.54 ?  169  THR A HG23 1 
ATOM   2403  N N    . PHE A 1 204 ? -10.521 10.820  18.244 1.00 10.97 ?  170  PHE A N    1 
ATOM   2404  C CA   . PHE A 1 204 ? -11.181 10.732  19.542 1.00 9.62  ?  170  PHE A CA   1 
ATOM   2405  C C    . PHE A 1 204 ? -12.209 11.855  19.589 1.00 9.94  ?  170  PHE A C    1 
ATOM   2406  O O    . PHE A 1 204 ? -11.832 13.035  19.637 1.00 11.24 ?  170  PHE A O    1 
ATOM   2407  C CB   . PHE A 1 204 ? -10.119 10.921  20.614 1.00 11.55 ?  170  PHE A CB   1 
ATOM   2408  C CG   . PHE A 1 204 ? -10.653 10.901  22.032 1.00 10.71 ?  170  PHE A CG   1 
ATOM   2409  C CD1  . PHE A 1 204 ? -11.383 11.958  22.590 1.00 13.22 ?  170  PHE A CD1  1 
ATOM   2410  C CD2  . PHE A 1 204 ? -10.355 9.847   22.841 1.00 11.58 ?  170  PHE A CD2  1 
ATOM   2411  C CE1  . PHE A 1 204 ? -11.823 11.908  23.906 1.00 11.43 ?  170  PHE A CE1  1 
ATOM   2412  C CE2  . PHE A 1 204 ? -10.775 9.841   24.172 1.00 11.87 ?  170  PHE A CE2  1 
ATOM   2413  C CZ   . PHE A 1 204 ? -11.513 10.854  24.675 1.00 11.59 ?  170  PHE A CZ   1 
ATOM   2414  H H    . PHE A 1 204 ? -9.982  11.489  18.204 1.00 13.16 ?  170  PHE A H    1 
ATOM   2415  H HA   . PHE A 1 204 ? -11.639 9.887   19.669 1.00 11.55 ?  170  PHE A HA   1 
ATOM   2416  H HB2  . PHE A 1 204 ? -9.469  10.205  20.535 1.00 13.86 ?  170  PHE A HB2  1 
ATOM   2417  H HB3  . PHE A 1 204 ? -9.688  11.778  20.475 1.00 13.86 ?  170  PHE A HB3  1 
ATOM   2418  H HD1  . PHE A 1 204 ? -11.576 12.705  22.071 1.00 15.86 ?  170  PHE A HD1  1 
ATOM   2419  H HD2  . PHE A 1 204 ? -9.870  9.129   22.505 1.00 13.90 ?  170  PHE A HD2  1 
ATOM   2420  H HE1  . PHE A 1 204 ? -12.333 12.605  24.253 1.00 13.72 ?  170  PHE A HE1  1 
ATOM   2421  H HE2  . PHE A 1 204 ? -10.542 9.128   24.722 1.00 14.24 ?  170  PHE A HE2  1 
ATOM   2422  H HZ   . PHE A 1 204 ? -11.807 10.820  25.556 1.00 13.91 ?  170  PHE A HZ   1 
ATOM   2423  N N    . ILE A 1 205 ? -13.491 11.508  19.552 1.00 10.84 ?  171  ILE A N    1 
ATOM   2424  C CA   . ILE A 1 205 ? -14.561 12.495  19.595 1.00 10.60 ?  171  ILE A CA   1 
ATOM   2425  C C    . ILE A 1 205 ? -14.967 12.756  21.030 1.00 10.62 ?  171  ILE A C    1 
ATOM   2426  O O    . ILE A 1 205 ? -15.302 11.827  21.768 1.00 11.57 ?  171  ILE A O    1 
ATOM   2427  C CB   . ILE A 1 205 ? -15.776 12.056  18.762 1.00 11.12 ?  171  ILE A CB   1 
ATOM   2428  C CG1  . ILE A 1 205 ? -15.344 11.763  17.323 1.00 12.21 ?  171  ILE A CG1  1 
ATOM   2429  C CG2  . ILE A 1 205 ? -16.842 13.164  18.806 1.00 12.67 ?  171  ILE A CG2  1 
ATOM   2430  C CD1  . ILE A 1 205 ? -14.600 12.887  16.648 1.00 14.56 ?  171  ILE A CD1  1 
ATOM   2431  H H    . ILE A 1 205 ? -13.770 10.696  19.501 1.00 13.01 ?  171  ILE A H    1 
ATOM   2432  H HA   . ILE A 1 205 ? -14.215 13.321  19.224 1.00 12.72 ?  171  ILE A HA   1 
ATOM   2433  H HB   . ILE A 1 205 ? -16.153 11.242  19.132 1.00 13.35 ?  171  ILE A HB   1 
ATOM   2434  H HG12 . ILE A 1 205 ? -14.760 10.988  17.328 1.00 14.66 ?  171  ILE A HG12 1 
ATOM   2435  H HG13 . ILE A 1 205 ? -16.136 11.578  16.795 1.00 14.66 ?  171  ILE A HG13 1 
ATOM   2436  H HG21 . ILE A 1 205 ? -17.568 12.928  18.207 1.00 15.21 ?  171  ILE A HG21 1 
ATOM   2437  H HG22 . ILE A 1 205 ? -17.175 13.246  19.713 1.00 15.21 ?  171  ILE A HG22 1 
ATOM   2438  H HG23 . ILE A 1 205 ? -16.439 14.000  18.525 1.00 15.21 ?  171  ILE A HG23 1 
ATOM   2439  H HD11 . ILE A 1 205 ? -14.499 12.678  15.706 1.00 17.48 ?  171  ILE A HD11 1 
ATOM   2440  H HD12 . ILE A 1 205 ? -15.106 13.708  16.752 1.00 17.48 ?  171  ILE A HD12 1 
ATOM   2441  H HD13 . ILE A 1 205 ? -13.727 12.982  17.061 1.00 17.48 ?  171  ILE A HD13 1 
ATOM   2442  N N    . ASP A 1 206 ? -14.951 14.035  21.418 1.00 9.97  ?  172  ASP A N    1 
ATOM   2443  C CA   . ASP A 1 206 ? -15.257 14.438  22.774 1.00 11.27 ?  172  ASP A CA   1 
ATOM   2444  C C    . ASP A 1 206 ? -16.509 15.310  22.772 1.00 10.00 ?  172  ASP A C    1 
ATOM   2445  O O    . ASP A 1 206 ? -16.814 15.983  21.794 1.00 10.94 ?  172  ASP A O    1 
ATOM   2446  C CB   . ASP A 1 206 ? -14.064 15.199  23.399 1.00 11.52 ?  172  ASP A CB   1 
ATOM   2447  C CG   . ASP A 1 206 ? -14.230 15.386  24.891 1.00 11.45 ?  172  ASP A CG   1 
ATOM   2448  O OD1  . ASP A 1 206 ? -14.888 14.545  25.532 1.00 11.52 ?  172  ASP A OD1  1 
ATOM   2449  O OD2  . ASP A 1 206 ? -13.647 16.381  25.414 1.00 11.82 ?  172  ASP A OD2  1 
ATOM   2450  H H    . ASP A 1 206 ? -14.760 14.692  20.897 1.00 11.97 ?  172  ASP A H    1 
ATOM   2451  H HA   . ASP A 1 206 ? -15.439 13.662  23.327 1.00 13.53 ?  172  ASP A HA   1 
ATOM   2452  H HB2  . ASP A 1 206 ? -13.250 14.695  23.246 1.00 13.82 ?  172  ASP A HB2  1 
ATOM   2453  H HB3  . ASP A 1 206 ? -13.995 16.075  22.990 1.00 13.82 ?  172  ASP A HB3  1 
ATOM   2454  N N    . ALA A 1 207 ? -17.182 15.279  23.925 1.00 11.56 ?  173  ALA A N    1 
ATOM   2455  C CA   . ALA A 1 207 ? -18.340 16.103  24.313 1.00 10.47 ?  173  ALA A CA   1 
ATOM   2456  C C    . ALA A 1 207 ? -19.659 15.601  23.774 1.00 10.95 ?  173  ALA A C    1 
ATOM   2457  O O    . ALA A 1 207 ? -20.684 16.300  23.817 1.00 11.75 ?  173  ALA A O    1 
ATOM   2458  C CB   . ALA A 1 207 ? -18.114 17.583  24.029 1.00 11.37 ?  173  ALA A CB   1 
ATOM   2459  H H    . ALA A 1 207 ? -16.969 14.739  24.559 1.00 13.87 ?  173  ALA A H    1 
ATOM   2460  H HA   . ALA A 1 207 ? -18.440 16.033  25.275 1.00 12.56 ?  173  ALA A HA   1 
ATOM   2461  H HB1  . ALA A 1 207 ? -18.894 18.083  24.318 1.00 13.65 ?  173  ALA A HB1  1 
ATOM   2462  H HB2  . ALA A 1 207 ? -17.330 17.882  24.515 1.00 13.65 ?  173  ALA A HB2  1 
ATOM   2463  H HB3  . ALA A 1 207 ? -17.979 17.705  23.076 1.00 13.65 ?  173  ALA A HB3  1 
ATOM   2464  N N    . ASN A 1 208 ? -19.652 14.352  23.312 1.00 10.74 ?  174  ASN A N    1 
ATOM   2465  C CA   . ASN A 1 208 ? -20.890 13.677  22.975 1.00 11.65 ?  174  ASN A CA   1 
ATOM   2466  C C    . ASN A 1 208 ? -21.901 13.799  24.089 1.00 11.43 ?  174  ASN A C    1 
ATOM   2467  O O    . ASN A 1 208 ? -23.104 13.967  23.821 1.00 11.44 ?  174  ASN A O    1 
ATOM   2468  C CB   . ASN A 1 208 ? -20.601 12.186  22.736 1.00 12.88 ?  174  ASN A CB   1 
ATOM   2469  C CG   . ASN A 1 208 ? -19.381 11.985  21.877 1.00 11.79 ?  174  ASN A CG   1 
ATOM   2470  O OD1  . ASN A 1 208 ? -18.257 12.020  22.375 1.00 15.52 ?  174  ASN A OD1  1 
ATOM   2471  N ND2  . ASN A 1 208 ? -19.553 11.737  20.633 1.00 15.59 ?  174  ASN A ND2  1 
ATOM   2472  H H    . ASN A 1 208 ? -18.945 13.880  23.187 1.00 12.89 ?  174  ASN A H    1 
ATOM   2473  H HA   . ASN A 1 208 ? -21.256 14.076  22.170 1.00 13.98 ?  174  ASN A HA   1 
ATOM   2474  H HB2  . ASN A 1 208 ? -20.449 11.749  23.588 1.00 15.46 ?  174  ASN A HB2  1 
ATOM   2475  H HB3  . ASN A 1 208 ? -21.360 11.782  22.286 1.00 15.46 ?  174  ASN A HB3  1 
ATOM   2476  H HD21 . ASN A 1 208 ? -18.873 11.618  20.121 1.00 18.71 ?  174  ASN A HD21 1 
ATOM   2477  H HD22 . ASN A 1 208 ? -20.349 11.690  20.310 1.00 18.71 ?  174  ASN A HD22 1 
ATOM   2478  N N    . ILE A 1 209 ? -21.462 13.646  25.324 1.00 11.04 ?  175  ILE A N    1 
ATOM   2479  C CA   . ILE A 1 209 ? -22.375 13.613  26.465 1.00 12.11 ?  175  ILE A CA   1 
ATOM   2480  C C    . ILE A 1 209 ? -22.974 14.988  26.727 1.00 11.31 ?  175  ILE A C    1 
ATOM   2481  O O    . ILE A 1 209 ? -24.135 15.087  27.143 1.00 12.46 ?  175  ILE A O    1 
ATOM   2482  C CB   . ILE A 1 209 ? -21.668 13.013  27.685 1.00 11.09 ?  175  ILE A CB   1 
ATOM   2483  C CG1  . ILE A 1 209 ? -21.376 11.549  27.365 1.00 12.51 ?  175  ILE A CG1  1 
ATOM   2484  C CG2  . ILE A 1 209 ? -22.520 13.172  28.966 1.00 12.73 ?  175  ILE A CG2  1 
ATOM   2485  C CD1  . ILE A 1 209 ? -20.466 10.895  28.359 1.00 14.98 ?  175  ILE A CD1  1 
ATOM   2486  H H    . ILE A 1 209 ? -20.634 13.557  25.538 1.00 13.24 ?  175  ILE A H    1 
ATOM   2487  H HA   . ILE A 1 209 ? -23.122 13.030  26.258 1.00 14.54 ?  175  ILE A HA   1 
ATOM   2488  H HB   . ILE A 1 209 ? -20.838 13.483  27.861 1.00 13.30 ?  175  ILE A HB   1 
ATOM   2489  H HG12 . ILE A 1 209 ? -22.211 11.056  27.357 1.00 15.02 ?  175  ILE A HG12 1 
ATOM   2490  H HG13 . ILE A 1 209 ? -20.952 11.496  26.494 1.00 15.02 ?  175  ILE A HG13 1 
ATOM   2491  H HG21 . ILE A 1 209 ? -22.126 12.642  29.676 1.00 15.27 ?  175  ILE A HG21 1 
ATOM   2492  H HG22 . ILE A 1 209 ? -22.536 14.108  29.220 1.00 15.27 ?  175  ILE A HG22 1 
ATOM   2493  H HG23 . ILE A 1 209 ? -23.422 12.863  28.785 1.00 15.27 ?  175  ILE A HG23 1 
ATOM   2494  H HD11 . ILE A 1 209 ? -20.269 9.993   28.062 1.00 17.97 ?  175  ILE A HD11 1 
ATOM   2495  H HD12 . ILE A 1 209 ? -19.645 11.409  28.422 1.00 17.97 ?  175  ILE A HD12 1 
ATOM   2496  H HD13 . ILE A 1 209 ? -20.907 10.871  29.223 1.00 17.97 ?  175  ILE A HD13 1 
ATOM   2497  N N    . LYS A 1 210 ? -22.233 16.070  26.454 1.00 11.03 ?  176  LYS A N    1 
ATOM   2498  C CA   . LYS A 1 210 ? -22.791 17.416  26.541 1.00 11.45 ?  176  LYS A CA   1 
ATOM   2499  C C    . LYS A 1 210 ? -23.898 17.628  25.532 1.00 12.04 ?  176  LYS A C    1 
ATOM   2500  O O    . LYS A 1 210 ? -24.849 18.364  25.807 1.00 12.47 ?  176  LYS A O    1 
ATOM   2501  C CB   . LYS A 1 210 ? -21.695 18.465  26.369 1.00 11.09 ?  176  LYS A CB   1 
ATOM   2502  C CG   . LYS A 1 210 ? -20.801 18.579  27.599 1.00 11.52 ?  176  LYS A CG   1 
ATOM   2503  C CD   . LYS A 1 210 ? -19.605 19.445  27.381 1.00 11.60 ?  176  LYS A CD   1 
ATOM   2504  C CE   . LYS A 1 210 ? -18.874 19.866  28.664 1.00 12.27 ?  176  LYS A CE   1 
ATOM   2505  N NZ   . LYS A 1 210 ? -18.216 18.707  29.291 1.00 11.50 ?  176  LYS A NZ   1 
ATOM   2506  H H    . LYS A 1 210 ? -21.406 16.048  26.216 1.00 13.23 ?  176  LYS A H    1 
ATOM   2507  H HA   . LYS A 1 210 ? -23.170 17.529  27.427 1.00 13.74 ?  176  LYS A HA   1 
ATOM   2508  H HB2  . LYS A 1 210 ? -21.139 18.221  25.612 1.00 13.31 ?  176  LYS A HB2  1 
ATOM   2509  H HB3  . LYS A 1 210 ? -22.106 19.330  26.213 1.00 13.31 ?  176  LYS A HB3  1 
ATOM   2510  H HG2  . LYS A 1 210 ? -21.316 18.960  28.327 1.00 13.83 ?  176  LYS A HG2  1 
ATOM   2511  H HG3  . LYS A 1 210 ? -20.487 17.694  27.843 1.00 13.83 ?  176  LYS A HG3  1 
ATOM   2512  H HD2  . LYS A 1 210 ? -18.970 18.961  26.829 1.00 13.92 ?  176  LYS A HD2  1 
ATOM   2513  H HD3  . LYS A 1 210 ? -19.888 20.255  26.928 1.00 13.92 ?  176  LYS A HD3  1 
ATOM   2514  H HE2  . LYS A 1 210 ? -18.197 20.527  28.449 1.00 14.72 ?  176  LYS A HE2  1 
ATOM   2515  H HE3  . LYS A 1 210 ? -19.512 20.237  29.293 1.00 14.72 ?  176  LYS A HE3  1 
ATOM   2516  H HZ1  . LYS A 1 210 ? -17.534 18.435  28.788 1.00 13.80 ?  176  LYS A HZ1  1 
ATOM   2517  H HZ2  . LYS A 1 210 ? -17.909 18.931  30.096 1.00 13.80 ?  176  LYS A HZ2  1 
ATOM   2518  H HZ3  . LYS A 1 210 ? -18.796 18.038  29.379 1.00 13.80 ?  176  LYS A HZ3  1 
ATOM   2519  N N    . VAL A 1 211 ? -23.785 17.036  24.330 1.00 11.66 ?  177  VAL A N    1 
ATOM   2520  C CA   . VAL A 1 211 ? -24.881 17.071  23.363 1.00 11.62 ?  177  VAL A CA   1 
ATOM   2521  C C    . VAL A 1 211 ? -26.060 16.269  23.853 1.00 11.63 ?  177  VAL A C    1 
ATOM   2522  O O    . VAL A 1 211 ? -27.215 16.714  23.708 1.00 12.20 ?  177  VAL A O    1 
ATOM   2523  C CB   . VAL A 1 211 ? -24.387 16.557  21.993 1.00 12.05 ?  177  VAL A CB   1 
ATOM   2524  C CG1  . VAL A 1 211 ? -25.586 16.356  21.048 1.00 12.88 ?  177  VAL A CG1  1 
ATOM   2525  C CG2  . VAL A 1 211 ? -23.348 17.487  21.427 1.00 13.84 ?  177  VAL A CG2  1 
ATOM   2526  H H    . VAL A 1 211 ? -23.088 16.613  24.057 1.00 13.99 ?  177  VAL A H    1 
ATOM   2527  H HA   . VAL A 1 211 ? -25.170 17.992  23.265 1.00 13.94 ?  177  VAL A HA   1 
ATOM   2528  H HB   . VAL A 1 211 ? -23.957 15.694  22.093 1.00 14.46 ?  177  VAL A HB   1 
ATOM   2529  H HG11 . VAL A 1 211 ? -25.259 16.080  20.178 1.00 15.46 ?  177  VAL A HG11 1 
ATOM   2530  H HG12 . VAL A 1 211 ? -26.166 15.670  21.416 1.00 15.46 ?  177  VAL A HG12 1 
ATOM   2531  H HG13 . VAL A 1 211 ? -26.071 17.192  20.970 1.00 15.46 ?  177  VAL A HG13 1 
ATOM   2532  H HG21 . VAL A 1 211 ? -23.084 17.169  20.549 1.00 16.61 ?  177  VAL A HG21 1 
ATOM   2533  H HG22 . VAL A 1 211 ? -23.726 18.378  21.357 1.00 16.61 ?  177  VAL A HG22 1 
ATOM   2534  H HG23 . VAL A 1 211 ? -22.580 17.499  22.019 1.00 16.61 ?  177  VAL A HG23 1 
ATOM   2535  N N    . LEU A 1 212 ? -25.814 15.076  24.377 1.00 11.03 ?  178  LEU A N    1 
ATOM   2536  C CA   . LEU A 1 212 ? -26.863 14.086  24.558 1.00 12.51 ?  178  LEU A CA   1 
ATOM   2537  C C    . LEU A 1 212 ? -27.600 14.177  25.887 1.00 14.25 ?  178  LEU A C    1 
ATOM   2538  O O    . LEU A 1 212 ? -28.726 13.670  25.983 1.00 15.68 ?  178  LEU A O    1 
ATOM   2539  C CB   . LEU A 1 212 ? -26.298 12.678  24.340 1.00 12.11 ?  178  LEU A CB   1 
ATOM   2540  C CG   . LEU A 1 212 ? -25.807 12.438  22.902 1.00 12.72 ?  178  LEU A CG   1 
ATOM   2541  C CD1  . LEU A 1 212 ? -24.968 11.195  22.835 1.00 14.08 ?  178  LEU A CD1  1 
ATOM   2542  C CD2  . LEU A 1 212 ? -26.979 12.346  21.973 1.00 14.69 ?  178  LEU A CD2  1 
ATOM   2543  H H    . LEU A 1 212 ? -25.039 14.813  24.638 1.00 13.24 ?  178  LEU A H    1 
ATOM   2544  H HA   . LEU A 1 212 ? -27.541 14.233  23.879 1.00 15.02 ?  178  LEU A HA   1 
ATOM   2545  H HB2  . LEU A 1 212 ? -25.547 12.547  24.939 1.00 14.53 ?  178  LEU A HB2  1 
ATOM   2546  H HB3  . LEU A 1 212 ? -26.993 12.029  24.532 1.00 14.53 ?  178  LEU A HB3  1 
ATOM   2547  H HG   . LEU A 1 212 ? -25.252 13.180  22.618 1.00 15.27 ?  178  LEU A HG   1 
ATOM   2548  H HD11 . LEU A 1 212 ? -24.747 11.013  21.909 1.00 16.90 ?  178  LEU A HD11 1 
ATOM   2549  H HD12 . LEU A 1 212 ? -24.157 11.334  23.348 1.00 16.90 ?  178  LEU A HD12 1 
ATOM   2550  H HD13 . LEU A 1 212 ? -25.472 10.454  23.207 1.00 16.90 ?  178  LEU A HD13 1 
ATOM   2551  H HD21 . LEU A 1 212 ? -26.659 12.148  21.079 1.00 17.63 ?  178  LEU A HD21 1 
ATOM   2552  H HD22 . LEU A 1 212 ? -27.569 11.639  22.277 1.00 17.63 ?  178  LEU A HD22 1 
ATOM   2553  H HD23 . LEU A 1 212 ? -27.450 13.194  21.975 1.00 17.63 ?  178  LEU A HD23 1 
ATOM   2554  N N    . VAL A 1 213 ? -27.037 14.812  26.909 1.00 13.27 ?  179  VAL A N    1 
ATOM   2555  C CA   . VAL A 1 213 ? -27.746 15.058  28.161 1.00 12.33 ?  179  VAL A CA   1 
ATOM   2556  C C    . VAL A 1 213 ? -28.540 16.347  27.972 1.00 13.00 ?  179  VAL A C    1 
ATOM   2557  O O    . VAL A 1 213 ? -27.934 17.421  27.841 1.00 13.10 ?  179  VAL A O    1 
ATOM   2558  C CB   . VAL A 1 213 ? -26.759 15.190  29.329 1.00 13.65 ?  179  VAL A CB   1 
ATOM   2559  C CG1  . VAL A 1 213 ? -27.446 15.716  30.580 1.00 15.27 ?  179  VAL A CG1  1 
ATOM   2560  C CG2  . VAL A 1 213 ? -26.095 13.846  29.647 1.00 14.84 ?  179  VAL A CG2  1 
ATOM   2561  H H    . VAL A 1 213 ? -26.232 15.114  26.902 1.00 15.92 ?  179  VAL A H    1 
ATOM   2562  H HA   . VAL A 1 213 ? -28.360 14.331  28.351 1.00 14.80 ?  179  VAL A HA   1 
ATOM   2563  H HB   . VAL A 1 213 ? -26.077 15.824  29.059 1.00 16.38 ?  179  VAL A HB   1 
ATOM   2564  H HG11 . VAL A 1 213 ? -26.930 15.452  31.358 1.00 18.33 ?  179  VAL A HG11 1 
ATOM   2565  H HG12 . VAL A 1 213 ? -27.495 16.684  30.529 1.00 18.33 ?  179  VAL A HG12 1 
ATOM   2566  H HG13 . VAL A 1 213 ? -28.339 15.341  30.631 1.00 18.33 ?  179  VAL A HG13 1 
ATOM   2567  H HG21 . VAL A 1 213 ? -25.350 13.997  30.249 1.00 17.81 ?  179  VAL A HG21 1 
ATOM   2568  H HG22 . VAL A 1 213 ? -26.747 13.263  30.067 1.00 17.81 ?  179  VAL A HG22 1 
ATOM   2569  H HG23 . VAL A 1 213 ? -25.778 13.447  28.822 1.00 17.81 ?  179  VAL A HG23 1 
ATOM   2570  N N    . PRO A 1 214 ? -29.880 16.294  27.848 1.00 13.06 ?  180  PRO A N    1 
ATOM   2571  C CA   . PRO A 1 214 ? -30.584 17.486  27.371 1.00 12.76 ?  180  PRO A CA   1 
ATOM   2572  C C    . PRO A 1 214 ? -30.343 18.739  28.181 1.00 11.68 ?  180  PRO A C    1 
ATOM   2573  O O    . PRO A 1 214 ? -30.293 19.830  27.615 1.00 12.11 ?  180  PRO A O    1 
ATOM   2574  C CB   . PRO A 1 214 ? -32.058 17.053  27.365 1.00 15.23 ?  180  PRO A CB   1 
ATOM   2575  C CG   . PRO A 1 214 ? -32.016 15.574  27.136 1.00 15.86 ?  180  PRO A CG   1 
ATOM   2576  C CD   . PRO A 1 214 ? -30.761 15.113  27.898 1.00 13.45 ?  180  PRO A CD   1 
ATOM   2577  H HA   . PRO A 1 214 ? -30.309 17.670  26.459 1.00 15.31 ?  180  PRO A HA   1 
ATOM   2578  H HB2  . PRO A 1 214 ? -32.469 17.263  28.218 1.00 18.27 ?  180  PRO A HB2  1 
ATOM   2579  H HB3  . PRO A 1 214 ? -32.533 17.503  26.648 1.00 18.27 ?  180  PRO A HB3  1 
ATOM   2580  H HG2  . PRO A 1 214 ? -32.816 15.157  27.495 1.00 19.04 ?  180  PRO A HG2  1 
ATOM   2581  H HG3  . PRO A 1 214 ? -31.940 15.384  26.188 1.00 19.04 ?  180  PRO A HG3  1 
ATOM   2582  H HD2  . PRO A 1 214 ? -30.979 14.883  28.815 1.00 16.14 ?  180  PRO A HD2  1 
ATOM   2583  H HD3  . PRO A 1 214 ? -30.348 14.355  27.455 1.00 16.14 ?  180  PRO A HD3  1 
ATOM   2584  N N    . SER A 1 215 ? -30.165 18.618  29.503 1.00 12.57 ?  181  SER A N    1 
ATOM   2585  C CA   . SER A 1 215 ? -30.059 19.826  30.307 1.00 12.56 ?  181  SER A CA   1 
ATOM   2586  C C    . SER A 1 215 ? -28.807 20.627  30.036 1.00 11.97 ?  181  SER A C    1 
ATOM   2587  O O    . SER A 1 215 ? -28.791 21.831  30.322 1.00 12.98 ?  181  SER A O    1 
ATOM   2588  C CB   . SER A 1 215 ? -30.156 19.550  31.813 1.00 13.90 ?  181  SER A CB   1 
ATOM   2589  O OG   . SER A 1 215 ? -28.971 18.883  32.263 1.00 14.25 ?  181  SER A OG   1 
ATOM   2590  H H    . SER A 1 215 ? -30.106 17.876  29.934 1.00 15.08 ?  181  SER A H    1 
ATOM   2591  H HA   . SER A 1 215 ? -30.829 20.364  30.064 1.00 15.07 ?  181  SER A HA   1 
ATOM   2592  H HB2  . SER A 1 215 ? -30.248 20.392  32.287 1.00 16.68 ?  181  SER A HB2  1 
ATOM   2593  H HB3  . SER A 1 215 ? -30.926 18.986  31.986 1.00 16.68 ?  181  SER A HB3  1 
ATOM   2594  H HG   . SER A 1 215 ? -28.978 18.082  32.009 1.00 17.10 ?  181  SER A HG   1 
ATOM   2595  N N    . PHE A 1 216 ? -27.743 20.002  29.516 1.00 11.31 ?  182  PHE A N    1 
ATOM   2596  C CA   . PHE A 1 216 ? -26.513 20.763  29.350 1.00 11.86 ?  182  PHE A CA   1 
ATOM   2597  C C    . PHE A 1 216 ? -26.725 21.951  28.421 1.00 12.80 ?  182  PHE A C    1 
ATOM   2598  O O    . PHE A 1 216 ? -26.388 23.093  28.754 1.00 12.63 ?  182  PHE A O    1 
ATOM   2599  C CB   . PHE A 1 216 ? -25.374 19.877  28.836 1.00 12.39 ?  182  PHE A CB   1 
ATOM   2600  C CG   . PHE A 1 216 ? -24.094 20.626  28.728 1.00 11.73 ?  182  PHE A CG   1 
ATOM   2601  C CD1  . PHE A 1 216 ? -23.295 20.828  29.840 1.00 13.39 ?  182  PHE A CD1  1 
ATOM   2602  C CD2  . PHE A 1 216 ? -23.715 21.221  27.544 1.00 11.53 ?  182  PHE A CD2  1 
ATOM   2603  C CE1  . PHE A 1 216 ? -22.137 21.580  29.762 1.00 11.59 ?  182  PHE A CE1  1 
ATOM   2604  C CE2  . PHE A 1 216 ? -22.567 22.007  27.457 1.00 11.92 ?  182  PHE A CE2  1 
ATOM   2605  C CZ   . PHE A 1 216 ? -21.782 22.182  28.582 1.00 12.54 ?  182  PHE A CZ   1 
ATOM   2606  H H    . PHE A 1 216 ? -27.714 19.179  29.266 1.00 13.58 ?  182  PHE A H    1 
ATOM   2607  H HA   . PHE A 1 216 ? -26.249 21.094  30.222 1.00 14.23 ?  182  PHE A HA   1 
ATOM   2608  H HB2  . PHE A 1 216 ? -25.243 19.139  29.451 1.00 14.87 ?  182  PHE A HB2  1 
ATOM   2609  H HB3  . PHE A 1 216 ? -25.604 19.540  27.956 1.00 14.87 ?  182  PHE A HB3  1 
ATOM   2610  H HD1  . PHE A 1 216 ? -23.541 20.452  30.654 1.00 16.07 ?  182  PHE A HD1  1 
ATOM   2611  H HD2  . PHE A 1 216 ? -24.238 21.096  26.785 1.00 13.84 ?  182  PHE A HD2  1 
ATOM   2612  H HE1  . PHE A 1 216 ? -21.598 21.678  30.513 1.00 13.90 ?  182  PHE A HE1  1 
ATOM   2613  H HE2  . PHE A 1 216 ? -22.332 22.408  26.652 1.00 14.30 ?  182  PHE A HE2  1 
ATOM   2614  H HZ   . PHE A 1 216 ? -21.015 22.707  28.538 1.00 15.05 ?  182  PHE A HZ   1 
ATOM   2615  N N    . PHE A 1 217 ? -27.275 21.719  27.226 1.00 12.03 ?  183  PHE A N    1 
ATOM   2616  C CA   . PHE A 1 217 ? -27.568 22.842  26.348 1.00 11.58 ?  183  PHE A CA   1 
ATOM   2617  C C    . PHE A 1 217 ? -28.948 23.438  26.562 1.00 12.04 ?  183  PHE A C    1 
ATOM   2618  O O    . PHE A 1 217 ? -29.090 24.637  26.324 1.00 12.52 ?  183  PHE A O    1 
ATOM   2619  C CB   . PHE A 1 217 ? -27.378 22.444  24.877 1.00 11.82 ?  183  PHE A CB   1 
ATOM   2620  C CG   . PHE A 1 217 ? -25.916 22.442  24.443 1.00 10.67 ?  183  PHE A CG   1 
ATOM   2621  C CD1  . PHE A 1 217 ? -25.153 23.566  24.551 1.00 12.05 ?  183  PHE A CD1  1 
ATOM   2622  C CD2  . PHE A 1 217 ? -25.365 21.289  23.945 1.00 12.43 ?  183  PHE A CD2  1 
ATOM   2623  C CE1  . PHE A 1 217 ? -23.791 23.548  24.153 1.00 11.73 ?  183  PHE A CE1  1 
ATOM   2624  C CE2  . PHE A 1 217 ? -24.027 21.241  23.570 1.00 12.77 ?  183  PHE A CE2  1 
ATOM   2625  C CZ   . PHE A 1 217 ? -23.256 22.384  23.666 1.00 12.55 ?  183  PHE A CZ   1 
ATOM   2626  H H    . PHE A 1 217 ? -27.480 20.944  26.915 1.00 14.44 ?  183  PHE A H    1 
ATOM   2627  H HA   . PHE A 1 217 ? -26.928 23.546  26.536 1.00 13.89 ?  183  PHE A HA   1 
ATOM   2628  H HB2  . PHE A 1 217 ? -27.731 21.550  24.744 1.00 14.19 ?  183  PHE A HB2  1 
ATOM   2629  H HB3  . PHE A 1 217 ? -27.856 23.076  24.316 1.00 14.19 ?  183  PHE A HB3  1 
ATOM   2630  H HD1  . PHE A 1 217 ? -25.527 24.348  24.887 1.00 14.46 ?  183  PHE A HD1  1 
ATOM   2631  H HD2  . PHE A 1 217 ? -25.893 20.529  23.858 1.00 14.92 ?  183  PHE A HD2  1 
ATOM   2632  H HE1  . PHE A 1 217 ? -23.269 24.315  24.222 1.00 14.08 ?  183  PHE A HE1  1 
ATOM   2633  H HE2  . PHE A 1 217 ? -23.655 20.448  23.258 1.00 15.33 ?  183  PHE A HE2  1 
ATOM   2634  H HZ   . PHE A 1 217 ? -22.365 22.362  23.398 1.00 15.06 ?  183  PHE A HZ   1 
ATOM   2635  N N    . SER A 1 218 ? -29.933 22.682  27.050 1.00 13.08 ?  184  SER A N    1 
ATOM   2636  C CA   . SER A 1 218 ? -31.240 23.357  27.181 1.00 13.14 ?  184  SER A CA   1 
ATOM   2637  C C    . SER A 1 218 ? -31.185 24.469  28.210 1.00 13.62 ?  184  SER A C    1 
ATOM   2638  O O    . SER A 1 218 ? -31.873 25.489  28.044 1.00 13.63 ?  184  SER A O    1 
ATOM   2639  C CB   . SER A 1 218 ? -32.362 22.409  27.525 1.00 13.90 ?  184  SER A CB   1 
ATOM   2640  O OG   . SER A 1 218 ? -32.276 21.941  28.842 1.00 17.47 ?  184  SER A OG   1 
ATOM   2641  H H    . SER A 1 218 ? -29.883 21.857  27.290 1.00 15.70 ?  184  SER A H    1 
ATOM   2642  H HA   . SER A 1 218 ? -31.449 23.726  26.309 1.00 15.77 ?  184  SER A HA   1 
ATOM   2643  H HB2  . SER A 1 218 ? -33.206 22.874  27.415 1.00 16.68 ?  184  SER A HB2  1 
ATOM   2644  H HB3  . SER A 1 218 ? -32.322 21.649  26.923 1.00 16.68 ?  184  SER A HB3  1 
ATOM   2645  H HG   . SER A 1 218 ? -32.691 21.215  28.917 1.00 20.97 ?  184  SER A HG   1 
ATOM   2646  N N    . SER A 1 219 ? -30.331 24.344  29.236 1.00 12.42 ?  185  SER A N    1 
ATOM   2647  C CA   . SER A 1 219 ? -30.163 25.365  30.255 1.00 14.25 ?  185  SER A CA   1 
ATOM   2648  C C    . SER A 1 219 ? -29.397 26.574  29.762 1.00 13.99 ?  185  SER A C    1 
ATOM   2649  O O    . SER A 1 219 ? -29.337 27.587  30.479 1.00 16.43 ?  185  SER A O    1 
ATOM   2650  C CB   . SER A 1 219 ? -29.458 24.820  31.491 1.00 13.37 ?  185  SER A CB   1 
ATOM   2651  O OG   . SER A 1 219 ? -28.117 24.383  31.180 1.00 15.60 ?  185  SER A OG   1 
ATOM   2652  H H    . SER A 1 219 ? -29.829 23.657  29.360 1.00 14.90 ?  185  SER A H    1 
ATOM   2653  H HA   . SER A 1 219 ? -31.053 25.642  30.521 1.00 17.10 ?  185  SER A HA   1 
ATOM   2654  H HB2  . SER A 1 219 ? -29.413 25.520  32.161 1.00 16.05 ?  185  SER A HB2  1 
ATOM   2655  H HB3  . SER A 1 219 ? -29.963 24.065  31.833 1.00 16.05 ?  185  SER A HB3  1 
ATOM   2656  H HG   . SER A 1 219 ? -28.138 23.624  30.821 1.00 18.72 ?  185  SER A HG   1 
ATOM   2657  N N    . LYS A 1 220 ? -28.801 26.503  28.572 1.00 13.92 ?  186  LYS A N    1 
ATOM   2658  C CA   . LYS A 1 220 ? -28.054 27.580  27.960 1.00 13.50 ?  186  LYS A CA   1 
ATOM   2659  C C    . LYS A 1 220 ? -28.775 28.227  26.790 1.00 12.74 ?  186  LYS A C    1 
ATOM   2660  O O    . LYS A 1 220 ? -28.713 29.437  26.628 1.00 13.74 ?  186  LYS A O    1 
ATOM   2661  C CB   . LYS A 1 220 ? -26.702 27.044  27.436 1.00 13.80 ?  186  LYS A CB   1 
ATOM   2662  C CG   . LYS A 1 220 ? -25.792 26.531  28.553 1.00 14.77 ?  186  LYS A CG   1 
ATOM   2663  C CD   . LYS A 1 220 ? -24.504 25.902  27.938 1.00 15.41 ?  186  LYS A CD   1 
ATOM   2664  C CE   . LYS A 1 220 ? -23.526 25.465  29.000 1.00 16.65 ?  186  LYS A CE   1 
ATOM   2665  N NZ   . LYS A 1 220 ? -24.091 24.535  29.982 1.00 16.72 ?  186  LYS A NZ   1 
ATOM   2666  H H    . LYS A 1 220 ? -28.822 25.799  28.078 1.00 16.70 ?  186  LYS A H    1 
ATOM   2667  H HA   . LYS A 1 220 ? -27.889 28.257  28.634 1.00 16.20 ?  186  LYS A HA   1 
ATOM   2668  H HB2  . LYS A 1 220 ? -26.869 26.309  26.825 1.00 16.56 ?  186  LYS A HB2  1 
ATOM   2669  H HB3  . LYS A 1 220 ? -26.236 27.759  26.975 1.00 16.56 ?  186  LYS A HB3  1 
ATOM   2670  H HG2  . LYS A 1 220 ? -25.535 27.267  29.131 1.00 17.72 ?  186  LYS A HG2  1 
ATOM   2671  H HG3  . LYS A 1 220 ? -26.256 25.852  29.068 1.00 17.72 ?  186  LYS A HG3  1 
ATOM   2672  H HD2  . LYS A 1 220 ? -24.748 25.123  27.413 1.00 18.49 ?  186  LYS A HD2  1 
ATOM   2673  H HD3  . LYS A 1 220 ? -24.066 26.558  27.374 1.00 18.49 ?  186  LYS A HD3  1 
ATOM   2674  H HE2  . LYS A 1 220 ? -22.778 25.022  28.571 1.00 19.98 ?  186  LYS A HE2  1 
ATOM   2675  H HE3  . LYS A 1 220 ? -23.216 26.249  29.480 1.00 19.98 ?  186  LYS A HE3  1 
ATOM   2676  H HZ1  . LYS A 1 220 ? -23.440 24.177  30.472 1.00 20.06 ?  186  LYS A HZ1  1 
ATOM   2677  H HZ2  . LYS A 1 220 ? -24.653 24.966  30.521 1.00 20.06 ?  186  LYS A HZ2  1 
ATOM   2678  H HZ3  . LYS A 1 220 ? -24.532 23.884  29.566 1.00 20.06 ?  186  LYS A HZ3  1 
ATOM   2679  N N    . VAL A 1 221 ? -29.399 27.422  25.931 1.00 13.07 ?  187  VAL A N    1 
ATOM   2680  C CA   . VAL A 1 221 ? -29.927 27.887  24.665 1.00 12.97 ?  187  VAL A CA   1 
ATOM   2681  C C    . VAL A 1 221 ? -31.364 27.462  24.430 1.00 13.72 ?  187  VAL A C    1 
ATOM   2682  O O    . VAL A 1 221 ? -31.906 27.745  23.348 1.00 14.34 ?  187  VAL A O    1 
ATOM   2683  C CB   . VAL A 1 221 ? -29.024 27.468  23.477 1.00 12.97 ?  187  VAL A CB   1 
ATOM   2684  C CG1  . VAL A 1 221 ? -27.662 28.077  23.608 1.00 15.06 ?  187  VAL A CG1  1 
ATOM   2685  C CG2  . VAL A 1 221 ? -28.905 25.939  23.363 1.00 13.38 ?  187  VAL A CG2  1 
ATOM   2686  H H    . VAL A 1 221 ? -29.529 26.583  26.068 1.00 15.68 ?  187  VAL A H    1 
ATOM   2687  H HA   . VAL A 1 221 ? -29.934 28.857  24.681 1.00 15.57 ?  187  VAL A HA   1 
ATOM   2688  H HB   . VAL A 1 221 ? -29.439 27.794  22.663 1.00 15.57 ?  187  VAL A HB   1 
ATOM   2689  H HG11 . VAL A 1 221 ? -27.178 27.951  22.777 1.00 18.07 ?  187  VAL A HG11 1 
ATOM   2690  H HG12 . VAL A 1 221 ? -27.756 29.024  23.795 1.00 18.07 ?  187  VAL A HG12 1 
ATOM   2691  H HG13 . VAL A 1 221 ? -27.189 27.642  24.335 1.00 18.07 ?  187  VAL A HG13 1 
ATOM   2692  H HG21 . VAL A 1 221 ? -28.454 25.719  22.533 1.00 16.06 ?  187  VAL A HG21 1 
ATOM   2693  H HG22 . VAL A 1 221 ? -28.394 25.605  24.116 1.00 16.06 ?  187  VAL A HG22 1 
ATOM   2694  H HG23 . VAL A 1 221 ? -29.795 25.552  23.369 1.00 16.06 ?  187  VAL A HG23 1 
ATOM   2695  N N    . GLY A 1 222 ? -31.992 26.774  25.397 1.00 12.99 ?  188  GLY A N    1 
ATOM   2696  C CA   . GLY A 1 222 ? -33.383 26.388  25.305 1.00 12.89 ?  188  GLY A CA   1 
ATOM   2697  C C    . GLY A 1 222 ? -33.596 24.986  24.760 1.00 14.18 ?  188  GLY A C    1 
ATOM   2698  O O    . GLY A 1 222 ? -32.706 24.363  24.175 1.00 13.09 ?  188  GLY A O    1 
ATOM   2699  H H    . GLY A 1 222 ? -31.614 26.520  26.126 1.00 15.59 ?  188  GLY A H    1 
ATOM   2700  H HA2  . GLY A 1 222 ? -33.781 26.430  26.188 1.00 15.47 ?  188  GLY A HA2  1 
ATOM   2701  H HA3  . GLY A 1 222 ? -33.845 27.010  24.721 1.00 15.47 ?  188  GLY A HA3  1 
ATOM   2702  N N    . VAL A 1 223 ? -34.824 24.476  24.945 1.00 13.14 ?  189  VAL A N    1 
ATOM   2703  C CA   . VAL A 1 223 ? -35.161 23.091  24.619 1.00 13.23 ?  189  VAL A CA   1 
ATOM   2704  C C    . VAL A 1 223 ? -35.091 22.839  23.111 1.00 12.35 ?  189  VAL A C    1 
ATOM   2705  O O    . VAL A 1 223 ? -34.588 21.794  22.662 1.00 12.94 ?  189  VAL A O    1 
ATOM   2706  C CB   . VAL A 1 223 ? -36.551 22.745  25.202 1.00 14.59 ?  189  VAL A CB   1 
ATOM   2707  C CG1  . VAL A 1 223 ? -37.116 21.453  24.626 1.00 16.93 ?  189  VAL A CG1  1 
ATOM   2708  C CG2  . VAL A 1 223 ? -36.504 22.708  26.727 1.00 16.55 ?  189  VAL A CG2  1 
ATOM   2709  H H    . VAL A 1 223 ? -35.488 24.922  25.262 1.00 15.77 ?  189  VAL A H    1 
ATOM   2710  H HA   . VAL A 1 223 ? -34.501 22.508  25.028 1.00 15.88 ?  189  VAL A HA   1 
ATOM   2711  H HB   . VAL A 1 223 ? -37.165 23.448  24.939 1.00 17.51 ?  189  VAL A HB   1 
ATOM   2712  H HG11 . VAL A 1 223 ? -37.934 21.228  25.096 1.00 20.31 ?  189  VAL A HG11 1 
ATOM   2713  H HG12 . VAL A 1 223 ? -37.302 21.582  23.682 1.00 20.31 ?  189  VAL A HG12 1 
ATOM   2714  H HG13 . VAL A 1 223 ? -36.464 20.744  24.741 1.00 20.31 ?  189  VAL A HG13 1 
ATOM   2715  H HG21 . VAL A 1 223 ? -37.361 22.401  27.062 1.00 19.86 ?  189  VAL A HG21 1 
ATOM   2716  H HG22 . VAL A 1 223 ? -35.802 22.099  27.006 1.00 19.86 ?  189  VAL A HG22 1 
ATOM   2717  H HG23 . VAL A 1 223 ? -36.318 23.600  27.059 1.00 19.86 ?  189  VAL A HG23 1 
ATOM   2718  N N    . ASN A 1 224 ? -35.655 23.746  22.301 1.00 14.09 ?  190  ASN A N    1 
ATOM   2719  C CA   . ASN A 1 224 ? -35.673 23.470  20.879 1.00 15.25 ?  190  ASN A CA   1 
ATOM   2720  C C    . ASN A 1 224 ? -34.254 23.473  20.300 1.00 14.05 ?  190  ASN A C    1 
ATOM   2721  O O    . ASN A 1 224 ? -33.902 22.596  19.501 1.00 14.05 ?  190  ASN A O    1 
ATOM   2722  C CB   . ASN A 1 224 ? -36.579 24.460  20.145 1.00 16.39 ?  190  ASN A CB   1 
ATOM   2723  C CG   . ASN A 1 224 ? -38.047 24.124  20.314 1.00 21.55 ?  190  ASN A CG   1 
ATOM   2724  O OD1  . ASN A 1 224 ? -38.457 22.999  20.084 1.00 29.84 ?  190  ASN A OD1  1 
ATOM   2725  N ND2  . ASN A 1 224 ? -38.821 25.099  20.723 1.00 25.76 ?  190  ASN A ND2  1 
ATOM   2726  H H    . ASN A 1 224 ? -36.013 24.488  22.547 1.00 16.90 ?  190  ASN A H    1 
ATOM   2727  H HA   . ASN A 1 224 ? -36.049 22.588  20.738 1.00 18.31 ?  190  ASN A HA   1 
ATOM   2728  H HB2  . ASN A 1 224 ? -36.430 25.351  20.498 1.00 19.67 ?  190  ASN A HB2  1 
ATOM   2729  H HB3  . ASN A 1 224 ? -36.371 24.440  19.198 1.00 19.67 ?  190  ASN A HB3  1 
ATOM   2730  H HD21 . ASN A 1 224 ? -38.487 25.876  20.879 1.00 30.91 ?  190  ASN A HD21 1 
ATOM   2731  H HD22 . ASN A 1 224 ? -39.663 24.962  20.836 1.00 30.91 ?  190  ASN A HD22 1 
ATOM   2732  N N    . LYS A 1 225 ? -33.433 24.429  20.704 1.00 13.19 ?  191  LYS A N    1 
ATOM   2733  C CA   . LYS A 1 225 ? -32.060 24.488  20.185 1.00 12.51 ?  191  LYS A CA   1 
ATOM   2734  C C    . LYS A 1 225 ? -31.252 23.264  20.615 1.00 12.89 ?  191  LYS A C    1 
ATOM   2735  O O    . LYS A 1 225 ? -30.497 22.699  19.813 1.00 13.51 ?  191  LYS A O    1 
ATOM   2736  C CB   . LYS A 1 225 ? -31.385 25.775  20.615 1.00 15.09 ?  191  LYS A CB   1 
ATOM   2737  C CG   . LYS A 1 225 ? -30.042 26.039  19.943 1.00 14.23 ?  191  LYS A CG   1 
ATOM   2738  C CD   . LYS A 1 225 ? -30.193 26.357  18.434 1.00 15.19 ?  191  LYS A CD   1 
ATOM   2739  C CE   . LYS A 1 225 ? -28.856 26.778  17.856 1.00 14.59 ?  191  LYS A CE   1 
ATOM   2740  N NZ   . LYS A 1 225 ? -28.982 27.311  16.468 1.00 15.00 ?  191  LYS A NZ   1 
ATOM   2741  H H    . LYS A 1 225 ? -33.633 25.048  21.267 1.00 15.82 ?  191  LYS A H    1 
ATOM   2742  H HA   . LYS A 1 225 ? -32.093 24.493  19.216 1.00 15.02 ?  191  LYS A HA   1 
ATOM   2743  H HB2  . LYS A 1 225 ? -31.970 26.518  20.401 1.00 18.10 ?  191  LYS A HB2  1 
ATOM   2744  H HB3  . LYS A 1 225 ? -31.231 25.739  21.572 1.00 18.10 ?  191  LYS A HB3  1 
ATOM   2745  H HG2  . LYS A 1 225 ? -29.617 26.799  20.370 1.00 17.07 ?  191  LYS A HG2  1 
ATOM   2746  H HG3  . LYS A 1 225 ? -29.482 25.252  20.031 1.00 17.07 ?  191  LYS A HG3  1 
ATOM   2747  H HD2  . LYS A 1 225 ? -30.501 25.566  17.962 1.00 18.23 ?  191  LYS A HD2  1 
ATOM   2748  H HD3  . LYS A 1 225 ? -30.826 27.082  18.314 1.00 18.23 ?  191  LYS A HD3  1 
ATOM   2749  H HE2  . LYS A 1 225 ? -28.474 27.474  18.413 1.00 17.51 ?  191  LYS A HE2  1 
ATOM   2750  H HE3  . LYS A 1 225 ? -28.264 26.010  17.832 1.00 17.51 ?  191  LYS A HE3  1 
ATOM   2751  H HZ1  . LYS A 1 225 ? -29.247 26.664  15.917 1.00 18.00 ?  191  LYS A HZ1  1 
ATOM   2752  H HZ2  . LYS A 1 225 ? -29.579 27.970  16.448 1.00 18.00 ?  191  LYS A HZ2  1 
ATOM   2753  H HZ3  . LYS A 1 225 ? -28.197 27.623  16.189 1.00 18.00 ?  191  LYS A HZ3  1 
ATOM   2754  N N    . GLN A 1 226 ? -31.490 22.748  21.830 1.00 12.08 ?  192  GLN A N    1 
ATOM   2755  C CA   . GLN A 1 226 ? -30.805 21.523  22.243 1.00 12.39 ?  192  GLN A CA   1 
ATOM   2756  C C    . GLN A 1 226 ? -31.172 20.373  21.331 1.00 12.95 ?  192  GLN A C    1 
ATOM   2757  O O    . GLN A 1 226 ? -30.314 19.579  20.931 1.00 13.16 ?  192  GLN A O    1 
ATOM   2758  C CB   . GLN A 1 226 ? -31.145 21.142  23.685 1.00 13.28 ?  192  GLN A CB   1 
ATOM   2759  C CG   . GLN A 1 226 ? -30.343 19.964  24.235 1.00 12.85 ?  192  GLN A CG   1 
ATOM   2760  C CD   . GLN A 1 226 ? -30.838 18.613  23.803 1.00 13.30 ?  192  GLN A CD   1 
ATOM   2761  O OE1  . GLN A 1 226 ? -32.036 18.419  23.555 1.00 14.01 ?  192  GLN A OE1  1 
ATOM   2762  N NE2  . GLN A 1 226 ? -29.946 17.634  23.747 1.00 13.63 ?  192  GLN A NE2  1 
ATOM   2763  H H    . GLN A 1 226 ? -32.027 23.080  22.414 1.00 14.50 ?  192  GLN A H    1 
ATOM   2764  H HA   . GLN A 1 226 ? -29.851 21.693  22.198 1.00 14.87 ?  192  GLN A HA   1 
ATOM   2765  H HB2  . GLN A 1 226 ? -30.972 21.907  24.256 1.00 15.93 ?  192  GLN A HB2  1 
ATOM   2766  H HB3  . GLN A 1 226 ? -32.084 20.903  23.728 1.00 15.93 ?  192  GLN A HB3  1 
ATOM   2767  H HG2  . GLN A 1 226 ? -29.425 20.049  23.934 1.00 15.42 ?  192  GLN A HG2  1 
ATOM   2768  H HG3  . GLN A 1 226 ? -30.379 19.992  25.204 1.00 15.42 ?  192  GLN A HG3  1 
ATOM   2769  H HE21 . GLN A 1 226 ? -29.125 17.788  23.954 1.00 16.35 ?  192  GLN A HE21 1 
ATOM   2770  H HE22 . GLN A 1 226 ? -30.188 16.845  23.505 1.00 16.35 ?  192  GLN A HE22 1 
ATOM   2771  N N    . ALA A 1 227 ? -32.474 20.253  20.978 1.00 12.89 ?  193  ALA A N    1 
ATOM   2772  C CA   . ALA A 1 227 ? -32.858 19.162  20.092 1.00 13.01 ?  193  ALA A CA   1 
ATOM   2773  C C    . ALA A 1 227 ? -32.239 19.313  18.718 1.00 11.94 ?  193  ALA A C    1 
ATOM   2774  O O    . ALA A 1 227 ? -31.889 18.311  18.072 1.00 13.79 ?  193  ALA A O    1 
ATOM   2775  C CB   . ALA A 1 227 ? -34.382 19.079  19.968 1.00 15.28 ?  193  ALA A CB   1 
ATOM   2776  H H    . ALA A 1 227 ? -33.113 20.771  21.231 1.00 15.47 ?  193  ALA A H    1 
ATOM   2777  H HA   . ALA A 1 227 ? -32.537 18.335  20.485 1.00 15.61 ?  193  ALA A HA   1 
ATOM   2778  H HB1  . ALA A 1 227 ? -34.612 18.334  19.391 1.00 18.33 ?  193  ALA A HB1  1 
ATOM   2779  H HB2  . ALA A 1 227 ? -34.764 18.945  20.850 1.00 18.33 ?  193  ALA A HB2  1 
ATOM   2780  H HB3  . ALA A 1 227 ? -34.714 19.907  19.587 1.00 18.33 ?  193  ALA A HB3  1 
ATOM   2781  N N    . GLU A 1 228 ? -32.115 20.536  18.254 1.00 12.41 ?  194  GLU A N    1 
ATOM   2782  C CA   . GLU A 1 228 ? -31.497 20.808  16.958 1.00 12.17 ?  194  GLU A CA   1 
ATOM   2783  C C    . GLU A 1 228 ? -30.001 20.480  16.979 1.00 15.06 ?  194  GLU A C    1 
ATOM   2784  O O    . GLU A 1 228 ? -29.471 19.868  16.032 1.00 13.22 ?  194  GLU A O    1 
ATOM   2785  C CB   . GLU A 1 228 ? -31.715 22.268  16.562 1.00 13.22 ?  194  GLU A CB   1 
ATOM   2786  C CG   . GLU A 1 228 ? -33.213 22.578  16.256 1.00 12.43 ?  194  GLU A CG   1 
ATOM   2787  C CD   . GLU A 1 228 ? -33.670 23.978  16.550 1.00 16.43 ?  194  GLU A CD   1 
ATOM   2788  O OE1  . GLU A 1 228 ? -32.861 24.888  16.699 1.00 15.22 ?  194  GLU A OE1  1 
ATOM   2789  O OE2  . GLU A 1 228 ? -34.926 24.190  16.643 1.00 19.59 ?  194  GLU A OE2  1 
ATOM   2790  H H    . GLU A 1 228 ? -32.380 21.242  18.668 1.00 14.89 ?  194  GLU A H    1 
ATOM   2791  H HA   . GLU A 1 228 ? -31.922 20.249  16.289 1.00 14.61 ?  194  GLU A HA   1 
ATOM   2792  H HB2  . GLU A 1 228 ? -31.431 22.841  17.291 1.00 15.86 ?  194  GLU A HB2  1 
ATOM   2793  H HB3  . GLU A 1 228 ? -31.197 22.463  15.766 1.00 15.86 ?  194  GLU A HB3  1 
ATOM   2794  H HG2  . GLU A 1 228 ? -33.369 22.419  15.312 1.00 14.91 ?  194  GLU A HG2  1 
ATOM   2795  H HG3  . GLU A 1 228 ? -33.762 21.981  16.788 1.00 14.91 ?  194  GLU A HG3  1 
ATOM   2796  N N    . ILE A 1 229 ? -29.303 20.855  18.057 1.00 12.37 ?  195  ILE A N    1 
ATOM   2797  C CA   . ILE A 1 229 ? -27.894 20.475  18.212 1.00 12.87 ?  195  ILE A CA   1 
ATOM   2798  C C    . ILE A 1 229 ? -27.758 18.956  18.174 1.00 12.79 ?  195  ILE A C    1 
ATOM   2799  O O    . ILE A 1 229 ? -26.874 18.416  17.498 1.00 13.13 ?  195  ILE A O    1 
ATOM   2800  C CB   . ILE A 1 229 ? -27.320 21.087  19.504 1.00 12.30 ?  195  ILE A CB   1 
ATOM   2801  C CG1  . ILE A 1 229 ? -27.212 22.591  19.378 1.00 12.04 ?  195  ILE A CG1  1 
ATOM   2802  C CG2  . ILE A 1 229 ? -25.958 20.454  19.837 1.00 13.51 ?  195  ILE A CG2  1 
ATOM   2803  C CD1  . ILE A 1 229 ? -26.993 23.323  20.724 1.00 12.08 ?  195  ILE A CD1  1 
ATOM   2804  H H    . ILE A 1 229 ? -29.617 21.325  18.705 1.00 14.85 ?  195  ILE A H    1 
ATOM   2805  H HA   . ILE A 1 229 ? -27.381 20.830  17.469 1.00 15.44 ?  195  ILE A HA   1 
ATOM   2806  H HB   . ILE A 1 229 ? -27.929 20.894  20.234 1.00 14.76 ?  195  ILE A HB   1 
ATOM   2807  H HG12 . ILE A 1 229 ? -26.461 22.802  18.802 1.00 14.45 ?  195  ILE A HG12 1 
ATOM   2808  H HG13 . ILE A 1 229 ? -28.034 22.930  18.988 1.00 14.45 ?  195  ILE A HG13 1 
ATOM   2809  H HG21 . ILE A 1 229 ? -25.549 20.949  20.564 1.00 16.21 ?  195  ILE A HG21 1 
ATOM   2810  H HG22 . ILE A 1 229 ? -26.094 19.531  20.100 1.00 16.21 ?  195  ILE A HG22 1 
ATOM   2811  H HG23 . ILE A 1 229 ? -25.391 20.493  19.050 1.00 16.21 ?  195  ILE A HG23 1 
ATOM   2812  H HD11 . ILE A 1 229 ? -26.864 24.268  20.552 1.00 14.50 ?  195  ILE A HD11 1 
ATOM   2813  H HD12 . ILE A 1 229 ? -27.774 23.192  21.285 1.00 14.50 ?  195  ILE A HD12 1 
ATOM   2814  H HD13 . ILE A 1 229 ? -26.208 22.955  21.159 1.00 14.50 ?  195  ILE A HD13 1 
ATOM   2815  N N    . GLU A 1 230 ? -28.626 18.240  18.887 1.00 11.27 ?  196  GLU A N    1 
ATOM   2816  C CA   . GLU A 1 230 ? -28.577 16.777  18.914 1.00 12.91 ?  196  GLU A CA   1 
ATOM   2817  C C    . GLU A 1 230 ? -28.798 16.202  17.525 1.00 13.04 ?  196  GLU A C    1 
ATOM   2818  O O    . GLU A 1 230 ? -28.100 15.287  17.101 1.00 12.70 ?  196  GLU A O    1 
ATOM   2819  C CB   . GLU A 1 230 ? -29.587 16.231  19.915 1.00 13.47 ?  196  GLU A CB   1 
ATOM   2820  C CG   . GLU A 1 230 ? -29.690 14.725  20.033 1.00 14.62 ?  196  GLU A CG   1 
ATOM   2821  C CD   . GLU A 1 230 ? -30.545 14.262  21.217 1.00 24.55 ?  196  GLU A CD   1 
ATOM   2822  O OE1  . GLU A 1 230 ? -30.600 14.955  22.284 1.00 22.28 ?  196  GLU A OE1  1 
ATOM   2823  O OE2  . GLU A 1 230 ? -31.165 13.210  21.096 1.00 31.89 ?  196  GLU A OE2  1 
ATOM   2824  H H    . GLU A 1 230 ? -29.256 18.576  19.366 1.00 13.53 ?  196  GLU A H    1 
ATOM   2825  H HA   . GLU A 1 230 ? -27.698 16.496  19.212 1.00 15.49 ?  196  GLU A HA   1 
ATOM   2826  H HB2  . GLU A 1 230 ? -29.350 16.568  20.794 1.00 16.16 ?  196  GLU A HB2  1 
ATOM   2827  H HB3  . GLU A 1 230 ? -30.465 16.555  19.662 1.00 16.16 ?  196  GLU A HB3  1 
ATOM   2828  H HG2  . GLU A 1 230 ? -30.090 14.373  19.222 1.00 17.54 ?  196  GLU A HG2  1 
ATOM   2829  H HG3  . GLU A 1 230 ? -28.799 14.358  20.149 1.00 17.54 ?  196  GLU A HG3  1 
ATOM   2830  N N    . ASN A 1 231 ? -29.828 16.695  16.811 1.00 12.96 ?  197  ASN A N    1 
ATOM   2831  C CA   . ASN A 1 231 ? -30.053 16.215  15.450 1.00 14.46 ?  197  ASN A CA   1 
ATOM   2832  C C    . ASN A 1 231 ? -28.812 16.385  14.582 1.00 12.35 ?  197  ASN A C    1 
ATOM   2833  O O    . ASN A 1 231 ? -28.425 15.482  13.819 1.00 13.07 ?  197  ASN A O    1 
ATOM   2834  C CB   . ASN A 1 231 ? -31.239 16.985  14.845 1.00 14.49 ?  197  ASN A CB   1 
ATOM   2835  C CG   . ASN A 1 231 ? -31.477 16.644  13.386 1.00 17.69 ?  197  ASN A CG   1 
ATOM   2836  O OD1  . ASN A 1 231 ? -31.960 15.556  13.077 1.00 21.52 ?  197  ASN A OD1  1 
ATOM   2837  N ND2  . ASN A 1 231 ? -31.161 17.561  12.492 1.00 19.51 ?  197  ASN A ND2  1 
ATOM   2838  H H    . ASN A 1 231 ? -30.387 17.287  17.087 1.00 15.55 ?  197  ASN A H    1 
ATOM   2839  H HA   . ASN A 1 231 ? -30.263 15.268  15.476 1.00 17.35 ?  197  ASN A HA   1 
ATOM   2840  H HB2  . ASN A 1 231 ? -32.044 16.765  15.340 1.00 17.39 ?  197  ASN A HB2  1 
ATOM   2841  H HB3  . ASN A 1 231 ? -31.062 17.937  14.906 1.00 17.39 ?  197  ASN A HB3  1 
ATOM   2842  H HD21 . ASN A 1 231 ? -30.834 18.315  12.746 1.00 23.41 ?  197  ASN A HD21 1 
ATOM   2843  H HD22 . ASN A 1 231 ? -31.281 17.406  11.655 1.00 23.41 ?  197  ASN A HD22 1 
ATOM   2844  N N    . SER A 1 232 ? -28.187 17.538  14.649 1.00 12.34 ?  198  SER A N    1 
ATOM   2845  C CA   . SER A 1 232 ? -27.008 17.788  13.837 1.00 12.84 ?  198  SER A CA   1 
ATOM   2846  C C    . SER A 1 232 ? -25.825 16.911  14.255 1.00 13.64 ?  198  SER A C    1 
ATOM   2847  O O    . SER A 1 232 ? -25.058 16.455  13.396 1.00 13.32 ?  198  SER A O    1 
ATOM   2848  C CB   . SER A 1 232 ? -26.632 19.244  13.898 1.00 12.33 ?  198  SER A CB   1 
ATOM   2849  O OG   . SER A 1 232 ? -27.662 20.067  13.340 1.00 13.70 ?  198  SER A OG   1 
ATOM   2850  H H    . SER A 1 232 ? -28.419 18.195  15.153 1.00 14.81 ?  198  SER A H    1 
ATOM   2851  H HA   . SER A 1 232 ? -27.225 17.570  12.917 1.00 15.41 ?  198  SER A HA   1 
ATOM   2852  H HB2  . SER A 1 232 ? -26.497 19.495  14.825 1.00 14.80 ?  198  SER A HB2  1 
ATOM   2853  H HB3  . SER A 1 232 ? -25.814 19.379  13.395 1.00 14.80 ?  198  SER A HB3  1 
ATOM   2854  H HG   . SER A 1 232 ? -27.813 19.838  12.546 1.00 16.44 ?  198  SER A HG   1 
ATOM   2855  N N    . TYR A 1 233 ? -25.658 16.690  15.567 1.00 11.62 ?  199  TYR A N    1 
ATOM   2856  C CA   . TYR A 1 233 ? -24.643 15.781  16.066 1.00 11.64 ?  199  TYR A CA   1 
ATOM   2857  C C    . TYR A 1 233 ? -24.796 14.403  15.433 1.00 12.53 ?  199  TYR A C    1 
ATOM   2858  O O    . TYR A 1 233 ? -23.818 13.817  14.937 1.00 11.78 ?  199  TYR A O    1 
ATOM   2859  C CB   . TYR A 1 233 ? -24.747 15.715  17.605 1.00 12.13 ?  199  TYR A CB   1 
ATOM   2860  C CG   . TYR A 1 233 ? -24.067 14.500  18.196 1.00 12.32 ?  199  TYR A CG   1 
ATOM   2861  C CD1  . TYR A 1 233 ? -22.690 14.511  18.469 1.00 13.20 ?  199  TYR A CD1  1 
ATOM   2862  C CD2  . TYR A 1 233 ? -24.758 13.349  18.483 1.00 12.92 ?  199  TYR A CD2  1 
ATOM   2863  C CE1  . TYR A 1 233 ? -22.075 13.410  18.997 1.00 13.34 ?  199  TYR A CE1  1 
ATOM   2864  C CE2  . TYR A 1 233 ? -24.120 12.255  19.010 1.00 14.16 ?  199  TYR A CE2  1 
ATOM   2865  C CZ   . TYR A 1 233 ? -22.777 12.301  19.242 1.00 13.85 ?  199  TYR A CZ   1 
ATOM   2866  O OH   . TYR A 1 233 ? -22.197 11.143  19.737 1.00 16.39 ?  199  TYR A OH   1 
ATOM   2867  H H    . TYR A 1 233 ? -26.127 17.060  16.185 1.00 13.94 ?  199  TYR A H    1 
ATOM   2868  H HA   . TYR A 1 233 ? -23.758 16.107  15.839 1.00 13.97 ?  199  TYR A HA   1 
ATOM   2869  H HB2  . TYR A 1 233 ? -24.328 16.504  17.983 1.00 14.56 ?  199  TYR A HB2  1 
ATOM   2870  H HB3  . TYR A 1 233 ? -25.684 15.684  17.855 1.00 14.56 ?  199  TYR A HB3  1 
ATOM   2871  H HD1  . TYR A 1 233 ? -22.191 15.276  18.289 1.00 15.84 ?  199  TYR A HD1  1 
ATOM   2872  H HD2  . TYR A 1 233 ? -25.672 13.310  18.317 1.00 15.51 ?  199  TYR A HD2  1 
ATOM   2873  H HE1  . TYR A 1 233 ? -21.164 13.433  19.186 1.00 16.01 ?  199  TYR A HE1  1 
ATOM   2874  H HE2  . TYR A 1 233 ? -24.602 11.485  19.209 1.00 16.99 ?  199  TYR A HE2  1 
ATOM   2875  H HH   . TYR A 1 233 ? -21.618 10.859  19.200 1.00 19.67 ?  199  TYR A HH   1 
ATOM   2876  N N    . PHE A 1 234 ? -26.023 13.858  15.409 1.00 11.70 ?  200  PHE A N    1 
ATOM   2877  C CA   . PHE A 1 234 ? -26.189 12.522  14.838 1.00 11.49 ?  200  PHE A CA   1 
ATOM   2878  C C    . PHE A 1 234 ? -25.830 12.534  13.355 1.00 11.90 ?  200  PHE A C    1 
ATOM   2879  O O    . PHE A 1 234 ? -25.227 11.578  12.868 1.00 13.13 ?  200  PHE A O    1 
ATOM   2880  C CB   . PHE A 1 234 ? -27.634 12.037  14.982 1.00 14.09 ?  200  PHE A CB   1 
ATOM   2881  C CG   . PHE A 1 234 ? -28.034 11.695  16.382 1.00 14.58 ?  200  PHE A CG   1 
ATOM   2882  C CD1  . PHE A 1 234 ? -27.230 10.963  17.199 1.00 15.85 ?  200  PHE A CD1  1 
ATOM   2883  C CD2  . PHE A 1 234 ? -29.285 12.087  16.864 1.00 18.46 ?  200  PHE A CD2  1 
ATOM   2884  C CE1  . PHE A 1 234 ? -27.648 10.638  18.523 1.00 17.01 ?  200  PHE A CE1  1 
ATOM   2885  C CE2  . PHE A 1 234 ? -29.688 11.764  18.139 1.00 20.52 ?  200  PHE A CE2  1 
ATOM   2886  C CZ   . PHE A 1 234 ? -28.889 11.077  18.960 1.00 17.12 ?  200  PHE A CZ   1 
ATOM   2887  H H    . PHE A 1 234 ? -26.741 14.227  15.706 1.00 14.04 ?  200  PHE A H    1 
ATOM   2888  H HA   . PHE A 1 234 ? -25.610 11.913  15.322 1.00 13.78 ?  200  PHE A HA   1 
ATOM   2889  H HB2  . PHE A 1 234 ? -28.228 12.738  14.671 1.00 16.90 ?  200  PHE A HB2  1 
ATOM   2890  H HB3  . PHE A 1 234 ? -27.749 11.240  14.441 1.00 16.90 ?  200  PHE A HB3  1 
ATOM   2891  H HD1  . PHE A 1 234 ? -26.402 10.672  16.892 1.00 19.02 ?  200  PHE A HD1  1 
ATOM   2892  H HD2  . PHE A 1 234 ? -29.855 12.575  16.314 1.00 22.15 ?  200  PHE A HD2  1 
ATOM   2893  H HE1  . PHE A 1 234 ? -27.098 10.140  19.084 1.00 20.41 ?  200  PHE A HE1  1 
ATOM   2894  H HE2  . PHE A 1 234 ? -30.530 12.028  18.433 1.00 24.62 ?  200  PHE A HE2  1 
ATOM   2895  H HZ   . PHE A 1 234 ? -29.166 10.892  19.828 1.00 20.55 ?  200  PHE A HZ   1 
ATOM   2896  N N    . SER A 1 235 ? -26.197 13.583  12.640 1.00 12.53 ?  201  SER A N    1 
ATOM   2897  C CA   . SER A 1 235 ? -25.842 13.695  11.225 1.00 13.27 ?  201  SER A CA   1 
ATOM   2898  C C    . SER A 1 235 ? -24.333 13.693  11.036 1.00 13.38 ?  201  SER A C    1 
ATOM   2899  O O    . SER A 1 235 ? -23.795 13.015  10.152 1.00 14.22 ?  201  SER A O    1 
ATOM   2900  C CB   . SER A 1 235 ? -26.462 14.978  10.663 1.00 17.69 ?  201  SER A CB   1 
ATOM   2901  O OG   . SER A 1 235 ? -26.151 15.162  9.298  1.00 22.72 ?  201  SER A OG   1 
ATOM   2902  H H    . SER A 1 235 ? -26.653 14.246  12.942 1.00 15.03 ?  201  SER A H    1 
ATOM   2903  H HA   . SER A 1 235 ? -26.196 12.937  10.735 1.00 15.93 ?  201  SER A HA   1 
ATOM   2904  H HB2  . SER A 1 235 ? -27.426 14.925  10.757 1.00 21.23 ?  201  SER A HB2  1 
ATOM   2905  H HB3  . SER A 1 235 ? -26.121 15.735  11.164 1.00 21.23 ?  201  SER A HB3  1 
ATOM   2906  H HG   . SER A 1 235 ? -25.318 15.213  9.198  1.00 27.27 ?  201  SER A HG   1 
ATOM   2907  N N    . MET A 1 236 ? -23.624 14.445  11.865 1.00 12.57 ?  202  MET A N    1 
ATOM   2908  C CA   . MET A 1 236 ? -22.173 14.543  11.757 1.00 11.53 ?  202  MET A CA   1 
ATOM   2909  C C    . MET A 1 236 ? -21.518 13.212  12.095 1.00 13.28 ?  202  MET A C    1 
ATOM   2910  O O    . MET A 1 236 ? -20.552 12.821  11.436 1.00 13.55 ?  202  MET A O    1 
ATOM   2911  C CB   . MET A 1 236 ? -21.854 15.636  12.768 1.00 14.24 ?  202  MET A CB   1 
ATOM   2912  C CG   . MET A 1 236 ? -21.948 17.048  12.217 1.00 12.49 ?  202  MET A CG   1 
ATOM   2913  S SD   . MET A 1 236 ? -21.905 18.276  13.546 1.00 14.73 ?  202  MET A SD   1 
ATOM   2914  C CE   . MET A 1 236 ? -20.093 18.436  13.526 1.00 18.42 ?  202  MET A CE   1 
ATOM   2915  H H    . MET A 1 236 ? -23.958 14.912  12.505 1.00 15.08 ?  202  MET A H    1 
ATOM   2916  H HA   . MET A 1 236 ? -21.844 14.770  10.873 1.00 13.83 ?  202  MET A HA   1 
ATOM   2917  H HB2  . MET A 1 236 ? -22.480 15.567  13.506 1.00 17.08 ?  202  MET A HB2  1 
ATOM   2918  H HB3  . MET A 1 236 ? -20.948 15.505  13.089 1.00 17.08 ?  202  MET A HB3  1 
ATOM   2919  H HG2  . MET A 1 236 ? -21.198 17.212  11.624 1.00 14.99 ?  202  MET A HG2  1 
ATOM   2920  H HG3  . MET A 1 236 ? -22.782 17.150  11.732 1.00 14.99 ?  202  MET A HG3  1 
ATOM   2921  H HE1  . MET A 1 236 ? -19.827 19.095  14.187 1.00 22.10 ?  202  MET A HE1  1 
ATOM   2922  H HE2  . MET A 1 236 ? -19.697 17.576  13.739 1.00 22.10 ?  202  MET A HE2  1 
ATOM   2923  H HE3  . MET A 1 236 ? -19.810 18.721  12.643 1.00 22.10 ?  202  MET A HE3  1 
ATOM   2924  N N    . MET A 1 237 ? -22.009 12.514  13.111 1.00 13.10 ?  203  MET A N    1 
ATOM   2925  C CA   . MET A 1 237 ? -21.417 11.224  13.463 1.00 12.28 ?  203  MET A CA   1 
ATOM   2926  C C    . MET A 1 237 ? -21.677 10.203  12.368 1.00 12.96 ?  203  MET A C    1 
ATOM   2927  O O    . MET A 1 237 ? -20.822 9.362   12.098 1.00 13.91 ?  203  MET A O    1 
ATOM   2928  C CB   . MET A 1 237 ? -22.040 10.773  14.763 1.00 11.90 ?  203  MET A CB   1 
ATOM   2929  C CG   . MET A 1 237 ? -21.553 11.506  16.036 1.00 12.34 ?  203  MET A CG   1 
ATOM   2930  S SD   . MET A 1 237 ? -19.835 11.924  16.247 1.00 13.07 ?  203  MET A SD   1 
ATOM   2931  C CE   . MET A 1 237 ? -19.630 13.465  15.387 1.00 13.58 ?  203  MET A CE   1 
ATOM   2932  H H    . MET A 1 237 ? -22.670 12.756  13.604 1.00 15.72 ?  203  MET A H    1 
ATOM   2933  H HA   . MET A 1 237 ? -20.459 11.310  13.580 1.00 14.73 ?  203  MET A HA   1 
ATOM   2934  H HB2  . MET A 1 237 ? -22.998 10.908  14.704 1.00 14.28 ?  203  MET A HB2  1 
ATOM   2935  H HB3  . MET A 1 237 ? -21.844 9.830   14.882 1.00 14.28 ?  203  MET A HB3  1 
ATOM   2936  H HG2  . MET A 1 237 ? -22.037 12.344  16.084 1.00 14.81 ?  203  MET A HG2  1 
ATOM   2937  H HG3  . MET A 1 237 ? -21.784 10.945  16.793 1.00 14.81 ?  203  MET A HG3  1 
ATOM   2938  H HE1  . MET A 1 237 ? -18.708 13.754  15.473 1.00 16.29 ?  203  MET A HE1  1 
ATOM   2939  H HE2  . MET A 1 237 ? -19.851 13.336  14.452 1.00 16.29 ?  203  MET A HE2  1 
ATOM   2940  H HE3  . MET A 1 237 ? -20.222 14.126  15.779 1.00 16.29 ?  203  MET A HE3  1 
ATOM   2941  N N    . SER A 1 238 ? -22.866 10.232  11.741 1.00 12.70 ?  204  SER A N    1 
ATOM   2942  C CA   . SER A 1 238 ? -23.116 9.351   10.597 1.00 13.12 ?  204  SER A CA   1 
ATOM   2943  C C    . SER A 1 238 ? -22.139 9.643   9.467  1.00 13.98 ?  204  SER A C    1 
ATOM   2944  O O    . SER A 1 238 ? -21.626 8.723   8.824  1.00 14.85 ?  204  SER A O    1 
ATOM   2945  C CB   . SER A 1 238 ? -24.537 9.588   10.096 1.00 17.24 ?  204  SER A CB   1 
ATOM   2946  O OG   . SER A 1 238 ? -25.468 9.008   10.982 1.00 26.71 ?  204  SER A OG   1 
ATOM   2947  H H    . SER A 1 238 ? -23.525 10.742  11.955 1.00 15.24 ?  204  SER A H    1 
ATOM   2948  H HA   . SER A 1 238 ? -23.013 8.427   10.873 1.00 15.75 ?  204  SER A HA   1 
ATOM   2949  H HB2  . SER A 1 238 ? -24.701 10.542  10.043 1.00 20.69 ?  204  SER A HB2  1 
ATOM   2950  H HB3  . SER A 1 238 ? -24.637 9.184   9.220  1.00 20.69 ?  204  SER A HB3  1 
ATOM   2951  H HG   . SER A 1 238 ? -26.250 9.203   10.745 1.00 32.05 ?  204  SER A HG   1 
ATOM   2952  N N    . ARG A 1 239 ? -21.834 10.896  9.221  1.00 13.10 ?  205  ARG A N    1 
ATOM   2953  C CA   . ARG A 1 239 ? -20.869 11.242  8.188  1.00 14.65 ?  205  ARG A CA   1 
ATOM   2954  C C    . ARG A 1 239 ? -19.493 10.666  8.510  1.00 14.33 ?  205  ARG A C    1 
ATOM   2955  O O    . ARG A 1 239 ? -18.830 10.069  7.645  1.00 14.79 ?  205  ARG A O    1 
ATOM   2956  C CB   . ARG A 1 239 ? -20.749 12.759  8.040  1.00 15.23 ?  205  ARG A CB   1 
ATOM   2957  C CG   . ARG A 1 239 ? -21.920 13.460  7.333  1.00 19.88 ?  205  ARG A CG   1 
ATOM   2958  C CD   . ARG A 1 239 ? -21.760 13.477  5.805  1.00 22.18 ?  205  ARG A CD   1 
ATOM   2959  N NE   . ARG A 1 239 ? -20.661 14.309  5.339  1.00 17.96 ?  205  ARG A NE   1 
ATOM   2960  C CZ   . ARG A 1 239 ? -20.740 15.622  5.165  1.00 18.10 ?  205  ARG A CZ   1 
ATOM   2961  N NH1  . ARG A 1 239 ? -21.847 16.288  5.436  1.00 18.19 ?  205  ARG A NH1  1 
ATOM   2962  N NH2  . ARG A 1 239 ? -19.669 16.266  4.731  1.00 18.67 ?  205  ARG A NH2  1 
ATOM   2963  H H    . ARG A 1 239 ? -22.167 11.572  9.634  1.00 15.72 ?  205  ARG A H    1 
ATOM   2964  H HA   . ARG A 1 239 ? -21.189 10.872  7.350  1.00 17.58 ?  205  ARG A HA   1 
ATOM   2965  H HB2  . ARG A 1 239 ? -20.677 13.145  8.927  1.00 18.28 ?  205  ARG A HB2  1 
ATOM   2966  H HB3  . ARG A 1 239 ? -19.948 12.952  7.529  1.00 18.28 ?  205  ARG A HB3  1 
ATOM   2967  H HG2  . ARG A 1 239 ? -22.743 12.992  7.543  1.00 23.86 ?  205  ARG A HG2  1 
ATOM   2968  H HG3  . ARG A 1 239 ? -21.973 14.378  7.640  1.00 23.86 ?  205  ARG A HG3  1 
ATOM   2969  H HD2  . ARG A 1 239 ? -21.595 12.572  5.498  1.00 26.62 ?  205  ARG A HD2  1 
ATOM   2970  H HD3  . ARG A 1 239 ? -22.577 13.818  5.409  1.00 26.62 ?  205  ARG A HD3  1 
ATOM   2971  H HE   . ARG A 1 239 ? -19.912 13.925  5.165  1.00 21.56 ?  205  ARG A HE   1 
ATOM   2972  H HH11 . ARG A 1 239 ? -22.539 15.871  5.732  1.00 21.83 ?  205  ARG A HH11 1 
ATOM   2973  H HH12 . ARG A 1 239 ? -21.877 17.140  5.316  1.00 21.83 ?  205  ARG A HH12 1 
ATOM   2974  H HH21 . ARG A 1 239 ? -18.943 15.833  4.569  1.00 22.40 ?  205  ARG A HH21 1 
ATOM   2975  H HH22 . ARG A 1 239 ? -19.698 17.117  4.612  1.00 22.40 ?  205  ARG A HH22 1 
ATOM   2976  N N    . LEU A 1 240 ? -19.012 10.842  9.758  1.00 13.89 ?  206  LEU A N    1 
ATOM   2977  C CA   . LEU A 1 240 ? -17.711 10.275  10.132 1.00 12.86 ?  206  LEU A CA   1 
ATOM   2978  C C    . LEU A 1 240 ? -17.704 8.757   10.112 1.00 14.38 ?  206  LEU A C    1 
ATOM   2979  O O    . LEU A 1 240 ? -16.705 8.140   9.695  1.00 13.66 ?  206  LEU A O    1 
ATOM   2980  C CB   . LEU A 1 240 ? -17.295 10.750  11.527 1.00 15.07 ?  206  LEU A CB   1 
ATOM   2981  C CG   . LEU A 1 240 ? -16.902 12.219  11.643 1.00 14.05 ?  206  LEU A CG   1 
ATOM   2982  C CD1  . LEU A 1 240 ? -16.401 12.423  13.084 1.00 16.67 ?  206  LEU A CD1  1 
ATOM   2983  C CD2  . LEU A 1 240 ? -15.853 12.648  10.654 1.00 16.15 ?  206  LEU A CD2  1 
ATOM   2984  H H    A LEU A 1 240 ? -19.411 11.273  10.386 0.26 16.67 ?  206  LEU A H    1 
ATOM   2985  H H    B LEU A 1 240 ? -19.411 11.273  10.386 0.74 16.67 ?  206  LEU A H    1 
ATOM   2986  H HA   . LEU A 1 240 ? -17.070 10.595  9.478  1.00 15.44 ?  206  LEU A HA   1 
ATOM   2987  H HB2  . LEU A 1 240 ? -18.040 10.604  12.131 1.00 18.09 ?  206  LEU A HB2  1 
ATOM   2988  H HB3  . LEU A 1 240 ? -16.531 10.224  11.810 1.00 18.09 ?  206  LEU A HB3  1 
ATOM   2989  H HG   . LEU A 1 240 ? -17.668 12.777  11.439 1.00 16.86 ?  206  LEU A HG   1 
ATOM   2990  H HD11 . LEU A 1 240 ? -16.156 13.354  13.204 1.00 20.01 ?  206  LEU A HD11 1 
ATOM   2991  H HD12 . LEU A 1 240 ? -17.110 12.185  13.702 1.00 20.01 ?  206  LEU A HD12 1 
ATOM   2992  H HD13 . LEU A 1 240 ? -15.628 11.856  13.233 1.00 20.01 ?  206  LEU A HD13 1 
ATOM   2993  H HD21 . LEU A 1 240 ? -15.574 13.554  10.862 1.00 19.38 ?  206  LEU A HD21 1 
ATOM   2994  H HD22 . LEU A 1 240 ? -15.095 12.046  10.716 1.00 19.38 ?  206  LEU A HD22 1 
ATOM   2995  H HD23 . LEU A 1 240 ? -16.229 12.615  9.760  1.00 19.38 ?  206  LEU A HD23 1 
ATOM   2996  N N    . LYS A 1 241 ? -18.809 8.108   10.525 1.00 13.02 ?  207  LYS A N    1 
ATOM   2997  C CA   . LYS A 1 241 ? -18.812 6.652   10.504 1.00 13.35 ?  207  LYS A CA   1 
ATOM   2998  C C    . LYS A 1 241 ? -18.504 6.154   9.103  1.00 15.10 ?  207  LYS A C    1 
ATOM   2999  O O    . LYS A 1 241 ? -17.798 5.152   8.941  1.00 17.07 ?  207  LYS A O    1 
ATOM   3000  C CB   . LYS A 1 241 ? -20.167 6.134   10.988 1.00 13.84 ?  207  LYS A CB   1 
ATOM   3001  C CG   . LYS A 1 241 ? -20.277 4.607   11.040 1.00 15.50 ?  207  LYS A CG   1 
ATOM   3002  C CD   . LYS A 1 241 ? -21.617 4.176   11.563 1.00 16.51 ?  207  LYS A CD   1 
ATOM   3003  C CE   . LYS A 1 241 ? -21.758 2.652   11.585 1.00 18.21 ?  207  LYS A CE   1 
ATOM   3004  N NZ   . LYS A 1 241 ? -23.053 2.256   12.225 1.00 20.80 ?  207  LYS A NZ   1 
ATOM   3005  H H    . LYS A 1 241 ? -19.531 8.478   10.808 1.00 15.62 ?  207  LYS A H    1 
ATOM   3006  H HA   . LYS A 1 241 ? -18.135 6.307   11.107 1.00 16.02 ?  207  LYS A HA   1 
ATOM   3007  H HB2  . LYS A 1 241 ? -20.325 6.471   11.884 1.00 16.61 ?  207  LYS A HB2  1 
ATOM   3008  H HB3  . LYS A 1 241 ? -20.856 6.458   10.386 1.00 16.61 ?  207  LYS A HB3  1 
ATOM   3009  H HG2  . LYS A 1 241 ? -20.166 4.245   10.147 1.00 18.59 ?  207  LYS A HG2  1 
ATOM   3010  H HG3  . LYS A 1 241 ? -19.591 4.254   11.628 1.00 18.59 ?  207  LYS A HG3  1 
ATOM   3011  H HD2  . LYS A 1 241 ? -21.726 4.504   12.470 1.00 19.81 ?  207  LYS A HD2  1 
ATOM   3012  H HD3  . LYS A 1 241 ? -22.314 4.537   10.993 1.00 19.81 ?  207  LYS A HD3  1 
ATOM   3013  H HE2  . LYS A 1 241 ? -21.744 2.311   10.677 1.00 21.86 ?  207  LYS A HE2  1 
ATOM   3014  H HE3  . LYS A 1 241 ? -21.029 2.265   12.096 1.00 21.86 ?  207  LYS A HE3  1 
ATOM   3015  H HZ1  . LYS A 1 241 ? -23.063 2.514   13.077 1.00 24.95 ?  207  LYS A HZ1  1 
ATOM   3016  H HZ2  . LYS A 1 241 ? -23.733 2.640   11.799 1.00 24.95 ?  207  LYS A HZ2  1 
ATOM   3017  H HZ3  . LYS A 1 241 ? -23.152 1.372   12.190 1.00 24.95 ?  207  LYS A HZ3  1 
ATOM   3018  N N    . GLU A 1 242 ? -19.034 6.817   8.087  1.00 14.42 ?  208  GLU A N    1 
ATOM   3019  C CA   . GLU A 1 242 ? -18.769 6.425   6.700  1.00 15.76 ?  208  GLU A CA   1 
ATOM   3020  C C    . GLU A 1 242 ? -17.386 6.879   6.228  1.00 17.39 ?  208  GLU A C    1 
ATOM   3021  O O    . GLU A 1 242 ? -16.629 6.070   5.672  1.00 16.59 ?  208  GLU A O    1 
ATOM   3022  C CB   . GLU A 1 242 ? -19.876 6.987   5.802  1.00 18.96 ?  208  GLU A CB   1 
ATOM   3023  H H    . GLU A 1 242 ? -19.552 7.499   8.167  1.00 17.30 ?  208  GLU A H    1 
ATOM   3024  H HA   . GLU A 1 242 ? -18.780 5.457   6.634  1.00 18.92 ?  208  GLU A HA   1 
ATOM   3025  N N    . SER A 1 243 ? -17.011 8.133   6.455  1.00 14.16 ?  209  SER A N    1 
ATOM   3026  C CA   . SER A 1 243 ? -15.750 8.600   5.881  1.00 13.44 ?  209  SER A CA   1 
ATOM   3027  C C    . SER A 1 243 ? -14.536 8.013   6.586  1.00 15.51 ?  209  SER A C    1 
ATOM   3028  O O    . SER A 1 243 ? -13.485 7.818   5.942  1.00 16.17 ?  209  SER A O    1 
ATOM   3029  C CB   . SER A 1 243 ? -15.659 10.105  5.889  1.00 15.98 ?  209  SER A CB   1 
ATOM   3030  O OG   . SER A 1 243 ? -15.676 10.587  7.216  1.00 16.94 ?  209  SER A OG   1 
ATOM   3031  H H    . SER A 1 243 ? -17.447 8.712   6.917  1.00 16.99 ?  209  SER A H    1 
ATOM   3032  H HA   . SER A 1 243 ? -15.738 8.307   4.956  1.00 16.13 ?  209  SER A HA   1 
ATOM   3033  H HB2  . SER A 1 243 ? -14.831 10.376  5.462  1.00 19.18 ?  209  SER A HB2  1 
ATOM   3034  H HB3  . SER A 1 243 ? -16.417 10.472  5.407  1.00 19.18 ?  209  SER A HB3  1 
ATOM   3035  H HG   . SER A 1 243 ? -15.808 11.417  7.218  1.00 20.33 ?  209  SER A HG   1 
ATOM   3036  N N    . LEU A 1 244 ? -14.672 7.632   7.861  1.00 13.61 ?  210  LEU A N    1 
ATOM   3037  C CA   . LEU A 1 244 ? -13.571 7.072   8.639  1.00 13.66 ?  210  LEU A CA   1 
ATOM   3038  C C    . LEU A 1 244 ? -13.710 5.580   8.807  1.00 14.21 ?  210  LEU A C    1 
ATOM   3039  O O    . LEU A 1 244 ? -13.135 4.984   9.708  1.00 13.62 ?  210  LEU A O    1 
ATOM   3040  C CB   . LEU A 1 244 ? -13.483 7.789   10.000 1.00 13.28 ?  210  LEU A CB   1 
ATOM   3041  C CG   . LEU A 1 244 ? -13.305 9.293   9.874  1.00 14.64 ?  210  LEU A CG   1 
ATOM   3042  C CD1  . LEU A 1 244 ? -13.011 9.801   11.317 1.00 14.15 ?  210  LEU A CD1  1 
ATOM   3043  C CD2  . LEU A 1 244 ? -12.179 9.695   8.973  1.00 15.60 ?  210  LEU A CD2  1 
ATOM   3044  H H    . LEU A 1 244 ? -15.408 7.692   8.302  1.00 16.33 ?  210  LEU A H    1 
ATOM   3045  H HA   . LEU A 1 244 ? -12.732 7.230   8.178  1.00 16.39 ?  210  LEU A HA   1 
ATOM   3046  H HB2  . LEU A 1 244 ? -14.301 7.624   10.495 1.00 15.94 ?  210  LEU A HB2  1 
ATOM   3047  H HB3  . LEU A 1 244 ? -12.723 7.438   10.490 1.00 15.94 ?  210  LEU A HB3  1 
ATOM   3048  H HG   . LEU A 1 244 ? -14.100 9.684   9.480  1.00 17.57 ?  210  LEU A HG   1 
ATOM   3049  H HD11 . LEU A 1 244 ? -12.946 10.769  11.303 1.00 16.99 ?  210  LEU A HD11 1 
ATOM   3050  H HD12 . LEU A 1 244 ? -13.734 9.526   11.902 1.00 16.99 ?  210  LEU A HD12 1 
ATOM   3051  H HD13 . LEU A 1 244 ? -12.174 9.418   11.622 1.00 16.99 ?  210  LEU A HD13 1 
ATOM   3052  H HD21 . LEU A 1 244 ? -11.960 10.625  9.137  1.00 18.71 ?  210  LEU A HD21 1 
ATOM   3053  H HD22 . LEU A 1 244 ? -11.409 9.136   9.160  1.00 18.71 ?  210  LEU A HD22 1 
ATOM   3054  H HD23 . LEU A 1 244 ? -12.456 9.578   8.051  1.00 18.71 ?  210  LEU A HD23 1 
ATOM   3055  N N    . SER A 1 245 ? -14.439 4.922   7.891  1.00 14.06 ?  211  SER A N    1 
ATOM   3056  C CA   . SER A 1 245 ? -14.653 3.492   8.006  1.00 15.02 ?  211  SER A CA   1 
ATOM   3057  C C    . SER A 1 245 ? -13.387 2.649   7.878  1.00 15.88 ?  211  SER A C    1 
ATOM   3058  O O    . SER A 1 245 ? -13.390 1.499   8.318  1.00 17.28 ?  211  SER A O    1 
ATOM   3059  C CB   . SER A 1 245 ? -15.686 3.023   6.966  1.00 17.29 ?  211  SER A CB   1 
ATOM   3060  O OG   . SER A 1 245 ? -15.165 3.165   5.668  1.00 18.58 ?  211  SER A OG   1 
ATOM   3061  H H    . SER A 1 245 ? -14.811 5.285   7.206  1.00 16.87 ?  211  SER A H    1 
ATOM   3062  H HA   . SER A 1 245 ? -15.004 3.334   8.896  1.00 18.03 ?  211  SER A HA   1 
ATOM   3063  H HB2  . SER A 1 245 ? -15.897 2.090   7.125  1.00 20.75 ?  211  SER A HB2  1 
ATOM   3064  H HB3  . SER A 1 245 ? -16.488 3.563   7.048  1.00 20.75 ?  211  SER A HB3  1 
ATOM   3065  H HG   . SER A 1 245 ? -15.768 3.029   5.100  1.00 22.30 ?  211  SER A HG   1 
ATOM   3066  N N    . ASN A 1 246 ? -12.322 3.193   7.303  1.00 14.80 ?  212  ASN A N    1 
ATOM   3067  C CA   . ASN A 1 246 ? -11.020 2.530   7.257  1.00 14.99 ?  212  ASN A CA   1 
ATOM   3068  C C    . ASN A 1 246 ? -10.055 3.070   8.299  1.00 16.75 ?  212  ASN A C    1 
ATOM   3069  O O    . ASN A 1 246 ? -8.846  2.891   8.181  1.00 16.80 ?  212  ASN A O    1 
ATOM   3070  C CB   . ASN A 1 246 ? -10.411 2.660   5.858  1.00 17.98 ?  212  ASN A CB   1 
ATOM   3071  C CG   . ASN A 1 246 ? -11.276 2.027   4.794  1.00 23.12 ?  212  ASN A CG   1 
ATOM   3072  O OD1  . ASN A 1 246 ? -11.693 0.902   4.939  1.00 24.25 ?  212  ASN A OD1  1 
ATOM   3073  N ND2  . ASN A 1 246 ? -11.572 2.780   3.747  1.00 26.99 ?  212  ASN A ND2  1 
ATOM   3074  H H    . ASN A 1 246 ? -12.326 3.964   6.922  1.00 17.75 ?  212  ASN A H    1 
ATOM   3075  H HA   . ASN A 1 246 ? -11.153 1.587   7.441  1.00 17.99 ?  212  ASN A HA   1 
ATOM   3076  H HB2  . ASN A 1 246 ? -10.307 3.600   5.642  1.00 21.57 ?  212  ASN A HB2  1 
ATOM   3077  H HB3  . ASN A 1 246 ? -9.547  2.219   5.845  1.00 21.57 ?  212  ASN A HB3  1 
ATOM   3078  H HD21 . ASN A 1 246 ? -12.062 2.463   3.115  1.00 32.39 ?  212  ASN A HD21 1 
ATOM   3079  H HD22 . ASN A 1 246 ? -11.274 3.585   3.698  1.00 32.39 ?  212  ASN A HD22 1 
ATOM   3080  N N    . ASN A 1 247 ? -10.593 3.723   9.329  1.00 13.32 ?  213  ASN A N    1 
ATOM   3081  C CA   . ASN A 1 247 ? -9.832  4.326   10.409 1.00 13.49 ?  213  ASN A CA   1 
ATOM   3082  C C    . ASN A 1 247 ? -10.538 3.971   11.713 1.00 12.47 ?  213  ASN A C    1 
ATOM   3083  O O    . ASN A 1 247 ? -11.496 3.188   11.746 1.00 14.88 ?  213  ASN A O    1 
ATOM   3084  C CB   . ASN A 1 247 ? -9.811  5.848   10.184 1.00 12.99 ?  213  ASN A CB   1 
ATOM   3085  C CG   . ASN A 1 247 ? -8.957  6.255   9.007  1.00 15.52 ?  213  ASN A CG   1 
ATOM   3086  O OD1  . ASN A 1 247 ? -9.467  6.632   7.946  1.00 15.24 ?  213  ASN A OD1  1 
ATOM   3087  N ND2  . ASN A 1 247 ? -7.673  6.215   9.200  1.00 14.17 ?  213  ASN A ND2  1 
ATOM   3088  H H    . ASN A 1 247 ? -11.440 3.834   9.425  1.00 15.99 ?  213  ASN A H    1 
ATOM   3089  H HA   . ASN A 1 247 ? -8.929  3.971   10.434 1.00 16.18 ?  213  ASN A HA   1 
ATOM   3090  H HB2  . ASN A 1 247 ? -10.715 6.155   10.018 1.00 15.59 ?  213  ASN A HB2  1 
ATOM   3091  H HB3  . ASN A 1 247 ? -9.454  6.279   10.976 1.00 15.59 ?  213  ASN A HB3  1 
ATOM   3092  H HD21 . ASN A 1 247 ? -7.136  6.435   8.566  1.00 17.01 ?  213  ASN A HD21 1 
ATOM   3093  H HD22 . ASN A 1 247 ? -7.360  5.968   9.962  1.00 17.01 ?  213  ASN A HD22 1 
ATOM   3094  N N    . LEU A 1 248 ? -10.080 4.544   12.822 1.00 11.95 ?  214  LEU A N    1 
ATOM   3095  C CA   . LEU A 1 248 ? -10.676 4.336   14.137 1.00 13.09 ?  214  LEU A CA   1 
ATOM   3096  C C    . LEU A 1 248 ? -11.411 5.588   14.631 1.00 12.06 ?  214  LEU A C    1 
ATOM   3097  O O    . LEU A 1 248 ? -10.929 6.719   14.465 1.00 12.80 ?  214  LEU A O    1 
ATOM   3098  C CB   . LEU A 1 248 ? -9.624  3.979   15.161 1.00 13.10 ?  214  LEU A CB   1 
ATOM   3099  C CG   . LEU A 1 248 ? -8.945  2.632   14.944 1.00 13.56 ?  214  LEU A CG   1 
ATOM   3100  C CD1  . LEU A 1 248 ? -7.813  2.398   15.916 1.00 14.64 ?  214  LEU A CD1  1 
ATOM   3101  C CD2  . LEU A 1 248 ? -9.960  1.474   15.072 1.00 15.58 ?  214  LEU A CD2  1 
ATOM   3102  H H    . LEU A 1 248 ? -9.404  5.074   12.838 1.00 14.34 ?  214  LEU A H    1 
ATOM   3103  H HA   . LEU A 1 248 ? -11.321 3.616   14.055 1.00 15.70 ?  214  LEU A HA   1 
ATOM   3104  H HB2  . LEU A 1 248 ? -8.933  4.660   15.141 1.00 15.72 ?  214  LEU A HB2  1 
ATOM   3105  H HB3  . LEU A 1 248 ? -10.043 3.957   16.036 1.00 15.72 ?  214  LEU A HB3  1 
ATOM   3106  H HG   . LEU A 1 248 ? -8.576  2.643   14.046 1.00 16.28 ?  214  LEU A HG   1 
ATOM   3107  H HD11 . LEU A 1 248 ? -7.378  1.559   15.698 1.00 17.57 ?  214  LEU A HD11 1 
ATOM   3108  H HD12 . LEU A 1 248 ? -7.178  3.128   15.843 1.00 17.57 ?  214  LEU A HD12 1 
ATOM   3109  H HD13 . LEU A 1 248 ? -8.172  2.361   16.816 1.00 17.57 ?  214  LEU A HD13 1 
ATOM   3110  H HD21 . LEU A 1 248 ? -9.484  0.630   15.036 1.00 18.70 ?  214  LEU A HD21 1 
ATOM   3111  H HD22 . LEU A 1 248 ? -10.427 1.555   15.918 1.00 18.70 ?  214  LEU A HD22 1 
ATOM   3112  H HD23 . LEU A 1 248 ? -10.594 1.527   14.339 1.00 18.70 ?  214  LEU A HD23 1 
ATOM   3113  N N    . ILE A 1 249 ? -12.566 5.382   15.255 1.00 12.94 ?  215  ILE A N    1 
ATOM   3114  C CA   . ILE A 1 249 ? -13.311 6.454   15.920 1.00 11.36 ?  215  ILE A CA   1 
ATOM   3115  C C    . ILE A 1 249 ? -13.589 6.001   17.340 1.00 13.36 ?  215  ILE A C    1 
ATOM   3116  O O    . ILE A 1 249 ? -14.310 5.004   17.570 1.00 12.98 ?  215  ILE A O    1 
ATOM   3117  C CB   . ILE A 1 249 ? -14.626 6.788   15.222 1.00 11.99 ?  215  ILE A CB   1 
ATOM   3118  C CG1  . ILE A 1 249 ? -14.498 6.869   13.707 1.00 14.68 ?  215  ILE A CG1  1 
ATOM   3119  C CG2  . ILE A 1 249 ? -15.143 8.134   15.744 1.00 13.43 ?  215  ILE A CG2  1 
ATOM   3120  C CD1  . ILE A 1 249 ? -15.869 7.112   13.020 1.00 15.66 ?  215  ILE A CD1  1 
ATOM   3121  H H    . ILE A 1 249 ? -12.950 4.614   15.308 1.00 15.52 ?  215  ILE A H    1 
ATOM   3122  H HA   . ILE A 1 249 ? -12.755 7.250   15.936 1.00 13.63 ?  215  ILE A HA   1 
ATOM   3123  H HB   . ILE A 1 249 ? -15.241 6.065   15.422 1.00 14.38 ?  215  ILE A HB   1 
ATOM   3124  H HG12 . ILE A 1 249 ? -13.908 7.603   13.476 1.00 17.62 ?  215  ILE A HG12 1 
ATOM   3125  H HG13 . ILE A 1 249 ? -14.135 6.033   13.373 1.00 17.62 ?  215  ILE A HG13 1 
ATOM   3126  H HG21 . ILE A 1 249 ? -16.029 8.294   15.382 1.00 16.12 ?  215  ILE A HG21 1 
ATOM   3127  H HG22 . ILE A 1 249 ? -15.183 8.102   16.713 1.00 16.12 ?  215  ILE A HG22 1 
ATOM   3128  H HG23 . ILE A 1 249 ? -14.538 8.836   15.461 1.00 16.12 ?  215  ILE A HG23 1 
ATOM   3129  H HD11 . ILE A 1 249 ? -15.788 6.915   12.074 1.00 18.79 ?  215  ILE A HD11 1 
ATOM   3130  H HD12 . ILE A 1 249 ? -16.532 6.529   13.423 1.00 18.79 ?  215  ILE A HD12 1 
ATOM   3131  H HD13 . ILE A 1 249 ? -16.125 8.039   13.145 1.00 18.79 ?  215  ILE A HD13 1 
ATOM   3132  N N    . LEU A 1 250 ? -13.003 6.704   18.305 1.00 11.96 ?  216  LEU A N    1 
ATOM   3133  C CA   . LEU A 1 250 ? -13.242 6.482   19.726 1.00 12.18 ?  216  LEU A CA   1 
ATOM   3134  C C    . LEU A 1 250 ? -14.078 7.644   20.218 1.00 13.43 ?  216  LEU A C    1 
ATOM   3135  O O    . LEU A 1 250 ? -13.877 8.760   19.756 1.00 17.41 ?  216  LEU A O    1 
ATOM   3136  C CB   . LEU A 1 250 ? -11.914 6.407   20.474 1.00 14.08 ?  216  LEU A CB   1 
ATOM   3137  C CG   . LEU A 1 250 ? -11.811 5.767   21.843 1.00 17.96 ?  216  LEU A CG   1 
ATOM   3138  C CD1  . LEU A 1 250 ? -12.176 4.295   21.778 1.00 21.93 ?  216  LEU A CD1  1 
ATOM   3139  C CD2  . LEU A 1 250 ? -10.430 5.938   22.391 1.00 19.25 ?  216  LEU A CD2  1 
ATOM   3140  H H    . LEU A 1 250 ? -12.442 7.339   18.154 1.00 14.35 ?  216  LEU A H    1 
ATOM   3141  H HA   . LEU A 1 250 ? -13.714 5.652   19.896 1.00 14.61 ?  216  LEU A HA   1 
ATOM   3142  H HB2  . LEU A 1 250 ? -11.299 5.915   19.907 1.00 16.90 ?  216  LEU A HB2  1 
ATOM   3143  H HB3  . LEU A 1 250 ? -11.603 7.319   20.587 1.00 16.90 ?  216  LEU A HB3  1 
ATOM   3144  H HG   . LEU A 1 250 ? -12.437 6.203   22.442 1.00 21.56 ?  216  LEU A HG   1 
ATOM   3145  H HD11 . LEU A 1 250 ? -12.277 3.955   22.681 1.00 26.31 ?  216  LEU A HD11 1 
ATOM   3146  H HD12 . LEU A 1 250 ? -13.009 4.197   21.292 1.00 26.31 ?  216  LEU A HD12 1 
ATOM   3147  H HD13 . LEU A 1 250 ? -11.468 3.814   21.321 1.00 26.31 ?  216  LEU A HD13 1 
ATOM   3148  H HD21 . LEU A 1 250 ? -10.384 5.522   23.266 1.00 23.10 ?  216  LEU A HD21 1 
ATOM   3149  H HD22 . LEU A 1 250 ? -9.797  5.514   21.790 1.00 23.10 ?  216  LEU A HD22 1 
ATOM   3150  H HD23 . LEU A 1 250 ? -10.234 6.885   22.464 1.00 23.10 ?  216  LEU A HD23 1 
ATOM   3151  N N    . ALA A 1 251 ? -14.997 7.432   21.141 1.00 11.33 ?  217  ALA A N    1 
ATOM   3152  C CA   . ALA A 1 251 ? -15.795 8.518   21.677 1.00 11.79 ?  217  ALA A CA   1 
ATOM   3153  C C    . ALA A 1 251 ? -15.838 8.471   23.199 1.00 11.59 ?  217  ALA A C    1 
ATOM   3154  O O    . ALA A 1 251 ? -15.839 7.414   23.812 1.00 11.72 ?  217  ALA A O    1 
ATOM   3155  C CB   . ALA A 1 251 ? -17.228 8.456   21.163 1.00 14.26 ?  217  ALA A CB   1 
ATOM   3156  H H    . ALA A 1 251 ? -15.180 6.661   21.476 1.00 13.60 ?  217  ALA A H    1 
ATOM   3157  H HA   . ALA A 1 251 ? -15.380 9.354   21.411 1.00 14.15 ?  217  ALA A HA   1 
ATOM   3158  H HB1  . ALA A 1 251 ? -17.715 9.227   21.493 1.00 17.11 ?  217  ALA A HB1  1 
ATOM   3159  H HB2  . ALA A 1 251 ? -17.216 8.463   20.193 1.00 17.11 ?  217  ALA A HB2  1 
ATOM   3160  H HB3  . ALA A 1 251 ? -17.643 7.640   21.483 1.00 17.11 ?  217  ALA A HB3  1 
ATOM   3161  N N    . ASN A 1 252 ? -15.920 9.648   23.807 1.00 12.43 ?  218  ASN A N    1 
ATOM   3162  C CA   . ASN A 1 252 ? -16.146 9.788   25.252 1.00 12.24 ?  218  ASN A CA   1 
ATOM   3163  C C    . ASN A 1 252 ? -17.648 9.665   25.457 1.00 11.81 ?  218  ASN A C    1 
ATOM   3164  O O    . ASN A 1 252 ? -18.377 10.654  25.456 1.00 12.38 ?  218  ASN A O    1 
ATOM   3165  C CB   . ASN A 1 252 ? -15.599 11.130  25.698 1.00 11.51 ?  218  ASN A CB   1 
ATOM   3166  C CG   . ASN A 1 252 ? -15.709 11.366  27.173 1.00 10.91 ?  218  ASN A CG   1 
ATOM   3167  O OD1  . ASN A 1 252 ? -16.137 10.520  27.950 1.00 11.58 ?  218  ASN A OD1  1 
ATOM   3168  N ND2  . ASN A 1 252 ? -15.272 12.550  27.581 1.00 11.73 ?  218  ASN A ND2  1 
ATOM   3169  H H    . ASN A 1 252 ? -15.847 10.402  23.399 1.00 14.92 ?  218  ASN A H    1 
ATOM   3170  H HA   . ASN A 1 252 ? -15.707 9.095   25.770 1.00 14.69 ?  218  ASN A HA   1 
ATOM   3171  H HB2  . ASN A 1 252 ? -14.660 11.179  25.460 1.00 13.81 ?  218  ASN A HB2  1 
ATOM   3172  H HB3  . ASN A 1 252 ? -16.093 11.833  25.248 1.00 13.81 ?  218  ASN A HB3  1 
ATOM   3173  H HD21 . ASN A 1 252 ? -15.304 12.756  28.416 1.00 14.08 ?  218  ASN A HD21 1 
ATOM   3174  H HD22 . ASN A 1 252 ? -14.957 13.112  27.012 1.00 14.08 ?  218  ASN A HD22 1 
ATOM   3175  N N    . ILE A 1 253 ? -18.131 8.426   25.603 1.00 11.25 ?  219  ILE A N    1 
ATOM   3176  C CA   . ILE A 1 253 ? -19.570 8.187   25.539 1.00 11.51 ?  219  ILE A CA   1 
ATOM   3177  C C    . ILE A 1 253 ? -20.157 7.285   26.624 1.00 12.47 ?  219  ILE A C    1 
ATOM   3178  O O    . ILE A 1 253 ? -21.268 7.553   27.117 1.00 14.06 ?  219  ILE A O    1 
ATOM   3179  C CB   . ILE A 1 253 ? -19.985 7.734   24.108 1.00 12.84 ?  219  ILE A CB   1 
ATOM   3180  C CG1  . ILE A 1 253 ? -21.516 7.650   23.939 1.00 14.38 ?  219  ILE A CG1  1 
ATOM   3181  C CG2  . ILE A 1 253 ? -19.347 6.427   23.703 1.00 14.39 ?  219  ILE A CG2  1 
ATOM   3182  C CD1  . ILE A 1 253 ? -22.232 8.946   24.177 1.00 16.30 ?  219  ILE A CD1  1 
ATOM   3183  H H    . ILE A 1 253 ? -17.653 7.724   25.738 1.00 13.50 ?  219  ILE A H    1 
ATOM   3184  H HA   . ILE A 1 253 ? -19.971 9.043   25.758 1.00 13.81 ?  219  ILE A HA   1 
ATOM   3185  H HB   . ILE A 1 253 ? -19.651 8.426   23.517 1.00 15.40 ?  219  ILE A HB   1 
ATOM   3186  H HG12 . ILE A 1 253 ? -21.713 7.367   23.033 1.00 17.26 ?  219  ILE A HG12 1 
ATOM   3187  H HG13 . ILE A 1 253 ? -21.863 7.002   24.572 1.00 17.26 ?  219  ILE A HG13 1 
ATOM   3188  H HG21 . ILE A 1 253 ? -19.617 6.212   22.796 1.00 17.27 ?  219  ILE A HG21 1 
ATOM   3189  H HG22 . ILE A 1 253 ? -18.383 6.519   23.748 1.00 17.27 ?  219  ILE A HG22 1 
ATOM   3190  H HG23 . ILE A 1 253 ? -19.642 5.730   24.309 1.00 17.27 ?  219  ILE A HG23 1 
ATOM   3191  H HD11 . ILE A 1 253 ? -23.151 8.858   23.881 1.00 19.56 ?  219  ILE A HD11 1 
ATOM   3192  H HD12 . ILE A 1 253 ? -22.208 9.151   25.125 1.00 19.56 ?  219  ILE A HD12 1 
ATOM   3193  H HD13 . ILE A 1 253 ? -21.789 9.648   23.675 1.00 19.56 ?  219  ILE A HD13 1 
ATOM   3194  N N    . ILE A 1 254 ? -19.481 6.205   27.019 1.00 11.56 ?  220  ILE A N    1 
ATOM   3195  C CA   . ILE A 1 254 ? -20.038 5.360   28.074 1.00 13.33 ?  220  ILE A CA   1 
ATOM   3196  C C    . ILE A 1 254 ? -19.891 6.080   29.403 1.00 12.81 ?  220  ILE A C    1 
ATOM   3197  O O    . ILE A 1 254 ? -18.790 6.469   29.806 1.00 13.21 ?  220  ILE A O    1 
ATOM   3198  C CB   . ILE A 1 254 ? -19.388 3.975   28.107 1.00 12.70 ?  220  ILE A CB   1 
ATOM   3199  C CG1  . ILE A 1 254 ? -19.724 3.152   26.867 1.00 14.45 ?  220  ILE A CG1  1 
ATOM   3200  C CG2  . ILE A 1 254 ? -19.778 3.224   29.399 1.00 14.44 ?  220  ILE A CG2  1 
ATOM   3201  C CD1  . ILE A 1 254 ? -18.963 1.823   26.760 1.00 16.23 ?  220  ILE A CD1  1 
ATOM   3202  H H    . ILE A 1 254 ? -18.724 5.949   26.703 1.00 13.88 ?  220  ILE A H    1 
ATOM   3203  H HA   . ILE A 1 254 ? -20.980 5.220   27.891 1.00 16.00 ?  220  ILE A HA   1 
ATOM   3204  H HB   . ILE A 1 254 ? -18.427 4.106   28.103 1.00 15.23 ?  220  ILE A HB   1 
ATOM   3205  H HG12 . ILE A 1 254 ? -20.672 2.947   26.880 1.00 17.34 ?  220  ILE A HG12 1 
ATOM   3206  H HG13 . ILE A 1 254 ? -19.509 3.677   26.080 1.00 17.34 ?  220  ILE A HG13 1 
ATOM   3207  H HG21 . ILE A 1 254 ? -19.570 2.283   29.293 1.00 17.33 ?  220  ILE A HG21 1 
ATOM   3208  H HG22 . ILE A 1 254 ? -19.275 3.593   30.142 1.00 17.33 ?  220  ILE A HG22 1 
ATOM   3209  H HG23 . ILE A 1 254 ? -20.729 3.338   29.555 1.00 17.33 ?  220  ILE A HG23 1 
ATOM   3210  H HD11 . ILE A 1 254 ? -18.988 1.518   25.839 1.00 19.47 ?  220  ILE A HD11 1 
ATOM   3211  H HD12 . ILE A 1 254 ? -18.044 1.962   27.037 1.00 19.47 ?  220  ILE A HD12 1 
ATOM   3212  H HD13 . ILE A 1 254 ? -19.387 1.169   27.337 1.00 19.47 ?  220  ILE A HD13 1 
ATOM   3213  N N    . ARG A 1 255 ? -20.999 6.232   30.108 1.00 13.31 ?  221  ARG A N    1 
ATOM   3214  C CA   . ARG A 1 255 ? -21.056 7.034   31.319 1.00 13.27 ?  221  ARG A CA   1 
ATOM   3215  C C    . ARG A 1 255 ? -22.352 6.732   32.049 1.00 14.10 ?  221  ARG A C    1 
ATOM   3216  O O    . ARG A 1 255 ? -23.412 6.734   31.433 1.00 13.52 ?  221  ARG A O    1 
ATOM   3217  C CB   . ARG A 1 255 ? -21.020 8.506   30.933 1.00 13.48 ?  221  ARG A CB   1 
ATOM   3218  C CG   . ARG A 1 255 ? -20.908 9.481   32.107 1.00 13.37 ?  221  ARG A CG   1 
ATOM   3219  C CD   . ARG A 1 255 ? -19.491 9.662   32.573 1.00 12.95 ?  221  ARG A CD   1 
ATOM   3220  N NE   . ARG A 1 255 ? -18.621 10.205  31.532 1.00 11.72 ?  221  ARG A NE   1 
ATOM   3221  C CZ   . ARG A 1 255 ? -18.594 11.477  31.171 1.00 12.66 ?  221  ARG A CZ   1 
ATOM   3222  N NH1  . ARG A 1 255 ? -19.397 12.375  31.736 1.00 13.36 ?  221  ARG A NH1  1 
ATOM   3223  N NH2  . ARG A 1 255 ? -17.754 11.866  30.214 1.00 12.48 ?  221  ARG A NH2  1 
ATOM   3224  H H    . ARG A 1 255 ? -21.752 5.871   29.903 1.00 15.98 ?  221  ARG A H    1 
ATOM   3225  H HA   . ARG A 1 255 ? -20.306 6.839   31.901 1.00 15.92 ?  221  ARG A HA   1 
ATOM   3226  H HB2  . ARG A 1 255 ? -20.252 8.654   30.359 1.00 16.18 ?  221  ARG A HB2  1 
ATOM   3227  H HB3  . ARG A 1 255 ? -21.837 8.719   30.456 1.00 16.18 ?  221  ARG A HB3  1 
ATOM   3228  H HG2  . ARG A 1 255 ? -21.248 10.347  31.833 1.00 16.04 ?  221  ARG A HG2  1 
ATOM   3229  H HG3  . ARG A 1 255 ? -21.429 9.141   32.852 1.00 16.04 ?  221  ARG A HG3  1 
ATOM   3230  H HD2  . ARG A 1 255 ? -19.481 10.276  33.324 1.00 15.54 ?  221  ARG A HD2  1 
ATOM   3231  H HD3  . ARG A 1 255 ? -19.135 8.801   32.844 1.00 15.54 ?  221  ARG A HD3  1 
ATOM   3232  H HE   . ARG A 1 255 ? -18.092 9.662   31.128 1.00 14.06 ?  221  ARG A HE   1 
ATOM   3233  H HH11 . ARG A 1 255 ? -19.948 12.132  32.349 1.00 16.04 ?  221  ARG A HH11 1 
ATOM   3234  H HH12 . ARG A 1 255 ? -19.364 13.197  31.487 1.00 16.04 ?  221  ARG A HH12 1 
ATOM   3235  H HH21 . ARG A 1 255 ? -17.235 11.293  29.838 1.00 14.97 ?  221  ARG A HH21 1 
ATOM   3236  H HH22 . ARG A 1 255 ? -17.729 12.691  29.973 1.00 14.97 ?  221  ARG A HH22 1 
ATOM   3237  N N    . VAL A 1 256 ? -22.282 6.479   33.361 1.00 14.14 ?  222  VAL A N    1 
ATOM   3238  C CA   . VAL A 1 256 ? -23.521 6.341   34.145 1.00 14.40 ?  222  VAL A CA   1 
ATOM   3239  C C    . VAL A 1 256 ? -24.258 7.672   34.105 1.00 13.70 ?  222  VAL A C    1 
ATOM   3240  O O    . VAL A 1 256 ? -23.712 8.695   34.555 1.00 15.85 ?  222  VAL A O    1 
ATOM   3241  C CB   . VAL A 1 256 ? -23.200 5.887   35.565 1.00 15.42 ?  222  VAL A CB   1 
ATOM   3242  C CG1  . VAL A 1 256 ? -24.438 5.932   36.450 1.00 16.11 ?  222  VAL A CG1  1 
ATOM   3243  C CG2  . VAL A 1 256 ? -22.605 4.487   35.553 1.00 16.35 ?  222  VAL A CG2  1 
ATOM   3244  H H    . VAL A 1 256 ? -21.554 6.386   33.810 1.00 16.97 ?  222  VAL A H    1 
ATOM   3245  H HA   . VAL A 1 256 ? -24.097 5.668   33.748 1.00 17.28 ?  222  VAL A HA   1 
ATOM   3246  H HB   . VAL A 1 256 ? -22.545 6.496   35.940 1.00 18.50 ?  222  VAL A HB   1 
ATOM   3247  H HG11 . VAL A 1 256 ? -24.217 5.569   37.321 1.00 19.33 ?  222  VAL A HG11 1 
ATOM   3248  H HG12 . VAL A 1 256 ? -24.728 6.853   36.540 1.00 19.33 ?  222  VAL A HG12 1 
ATOM   3249  H HG13 . VAL A 1 256 ? -25.140 5.403   36.039 1.00 19.33 ?  222  VAL A HG13 1 
ATOM   3250  H HG21 . VAL A 1 256 ? -22.452 4.201   36.467 1.00 19.62 ?  222  VAL A HG21 1 
ATOM   3251  H HG22 . VAL A 1 256 ? -23.227 3.883   35.117 1.00 19.62 ?  222  VAL A HG22 1 
ATOM   3252  H HG23 . VAL A 1 256 ? -21.766 4.504   35.067 1.00 19.62 ?  222  VAL A HG23 1 
ATOM   3253  N N    . ARG A 1 257 ? -25.488 7.664   33.613 1.00 14.60 ?  223  ARG A N    1 
ATOM   3254  C CA   . ARG A 1 257 ? -26.305 8.866   33.497 1.00 15.46 ?  223  ARG A CA   1 
ATOM   3255  C C    . ARG A 1 257 ? -27.757 8.485   33.719 1.00 17.45 ?  223  ARG A C    1 
ATOM   3256  O O    . ARG A 1 257 ? -28.234 7.556   33.051 1.00 16.86 ?  223  ARG A O    1 
ATOM   3257  C CB   . ARG A 1 257 ? -26.231 9.534   32.126 1.00 16.76 ?  223  ARG A CB   1 
ATOM   3258  C CG   . ARG A 1 257 ? -24.904 10.124  31.714 1.00 14.65 ?  223  ARG A CG   1 
ATOM   3259  C CD   . ARG A 1 257 ? -24.426 11.280  32.595 1.00 15.32 ?  223  ARG A CD   1 
ATOM   3260  N NE   . ARG A 1 257 ? -25.455 12.253  32.912 1.00 14.99 ?  223  ARG A NE   1 
ATOM   3261  C CZ   . ARG A 1 257 ? -25.230 13.383  33.563 1.00 15.82 ?  223  ARG A CZ   1 
ATOM   3262  N NH1  . ARG A 1 257 ? -24.026 13.728  33.949 1.00 15.26 ?  223  ARG A NH1  1 
ATOM   3263  N NH2  . ARG A 1 257 ? -26.264 14.159  33.869 1.00 16.45 ?  223  ARG A NH2  1 
ATOM   3264  H H    . ARG A 1 257 ? -25.885 6.955   33.332 1.00 17.52 ?  223  ARG A H    1 
ATOM   3265  H HA   . ARG A 1 257 ? -25.992 9.481   34.179 1.00 18.55 ?  223  ARG A HA   1 
ATOM   3266  H HB2  . ARG A 1 257 ? -26.462 8.869   31.458 1.00 20.11 ?  223  ARG A HB2  1 
ATOM   3267  H HB3  . ARG A 1 257 ? -26.877 10.257  32.111 1.00 20.11 ?  223  ARG A HB3  1 
ATOM   3268  H HG2  . ARG A 1 257 ? -24.229 9.429   31.754 1.00 17.58 ?  223  ARG A HG2  1 
ATOM   3269  H HG3  . ARG A 1 257 ? -24.981 10.460  30.808 1.00 17.58 ?  223  ARG A HG3  1 
ATOM   3270  H HD2  . ARG A 1 257 ? -24.098 10.917  33.433 1.00 18.39 ?  223  ARG A HD2  1 
ATOM   3271  H HD3  . ARG A 1 257 ? -23.713 11.748  32.134 1.00 18.39 ?  223  ARG A HD3  1 
ATOM   3272  H HE   . ARG A 1 257 ? -26.260 12.085  32.661 1.00 17.99 ?  223  ARG A HE   1 
ATOM   3273  H HH11 . ARG A 1 257 ? -23.357 13.215  33.779 1.00 18.32 ?  223  ARG A HH11 1 
ATOM   3274  H HH12 . ARG A 1 257 ? -23.905 14.467  34.371 1.00 18.32 ?  223  ARG A HH12 1 
ATOM   3275  H HH21 . ARG A 1 257 ? -27.060 13.923  33.644 1.00 19.74 ?  223  ARG A HH21 1 
ATOM   3276  H HH22 . ARG A 1 257 ? -26.138 14.897  34.292 1.00 19.74 ?  223  ARG A HH22 1 
ATOM   3277  N N    . PRO A 1 258 ? -28.501 9.208   34.559 1.00 18.02 ?  224  PRO A N    1 
ATOM   3278  C CA   . PRO A 1 258 ? -29.927 8.892   34.647 1.00 17.85 ?  224  PRO A CA   1 
ATOM   3279  C C    . PRO A 1 258 ? -30.645 9.075   33.323 1.00 21.81 ?  224  PRO A C    1 
ATOM   3280  O O    . PRO A 1 258 ? -31.633 8.381   33.046 1.00 20.02 ?  224  PRO A O    1 
ATOM   3281  C CB   . PRO A 1 258 ? -30.452 9.845   35.734 1.00 22.75 ?  224  PRO A CB   1 
ATOM   3282  C CG   . PRO A 1 258 ? -29.399 10.802  36.007 1.00 27.27 ?  224  PRO A CG   1 
ATOM   3283  C CD   . PRO A 1 258 ? -28.079 10.239  35.517 1.00 17.04 ?  224  PRO A CD   1 
ATOM   3284  H HA   . PRO A 1 258 ? -30.051 7.983   34.962 1.00 21.42 ?  224  PRO A HA   1 
ATOM   3285  H HB2  . PRO A 1 258 ? -31.246 10.298  35.408 1.00 27.30 ?  224  PRO A HB2  1 
ATOM   3286  H HB3  . PRO A 1 258 ? -30.664 9.337   36.532 1.00 27.30 ?  224  PRO A HB3  1 
ATOM   3287  H HG2  . PRO A 1 258 ? -29.600 11.630  35.544 1.00 32.72 ?  224  PRO A HG2  1 
ATOM   3288  H HG3  . PRO A 1 258 ? -29.358 10.958  36.964 1.00 32.72 ?  224  PRO A HG3  1 
ATOM   3289  H HD2  . PRO A 1 258 ? -27.551 10.925  35.079 1.00 20.45 ?  224  PRO A HD2  1 
ATOM   3290  H HD3  . PRO A 1 258 ? -27.575 9.849   36.248 1.00 20.45 ?  224  PRO A HD3  1 
ATOM   3291  N N    . GLU A 1 259 ? -30.169 9.990   32.472 1.00 17.89 ?  225  GLU A N    1 
ATOM   3292  C CA   . GLU A 1 259 ? -30.783 10.270  31.195 1.00 19.07 ?  225  GLU A CA   1 
ATOM   3293  C C    . GLU A 1 259 ? -30.517 9.193   30.153 1.00 18.19 ?  225  GLU A C    1 
ATOM   3294  O O    . GLU A 1 259 ? -31.181 9.184   29.108 1.00 20.35 ?  225  GLU A O    1 
ATOM   3295  C CB   . GLU A 1 259 ? -30.240 11.614  30.658 1.00 18.04 ?  225  GLU A CB   1 
ATOM   3296  C CG   . GLU A 1 259 ? -30.382 12.776  31.629 1.00 18.55 ?  225  GLU A CG   1 
ATOM   3297  C CD   . GLU A 1 259 ? -29.202 12.948  32.578 1.00 19.27 ?  225  GLU A CD   1 
ATOM   3298  O OE1  . GLU A 1 259 ? -28.304 12.081  32.663 1.00 17.36 ?  225  GLU A OE1  1 
ATOM   3299  O OE2  . GLU A 1 259 ? -29.123 13.960  33.319 1.00 18.87 ?  225  GLU A OE2  1 
ATOM   3300  H H    . GLU A 1 259 ? -29.472 10.470  32.625 1.00 21.47 ?  225  GLU A H    1 
ATOM   3301  H HA   . GLU A 1 259 ? -31.742 10.327  31.326 1.00 22.88 ?  225  GLU A HA   1 
ATOM   3302  H HB2  . GLU A 1 259 ? -29.296 11.510  30.459 1.00 21.65 ?  225  GLU A HB2  1 
ATOM   3303  H HB3  . GLU A 1 259 ? -30.726 11.844  29.851 1.00 21.65 ?  225  GLU A HB3  1 
ATOM   3304  H HG2  . GLU A 1 259 ? -30.471 13.596  31.119 1.00 22.26 ?  225  GLU A HG2  1 
ATOM   3305  H HG3  . GLU A 1 259 ? -31.175 12.633  32.169 1.00 22.26 ?  225  GLU A HG3  1 
ATOM   3306  N N    . PHE A 1 260 ? -29.537 8.322   30.380 1.00 17.28 ?  226  PHE A N    1 
ATOM   3307  C CA   . PHE A 1 260 ? -29.173 7.295   29.411 1.00 16.29 ?  226  PHE A CA   1 
ATOM   3308  C C    . PHE A 1 260 ? -29.666 5.940   29.936 1.00 16.89 ?  226  PHE A C    1 
ATOM   3309  O O    . PHE A 1 260 ? -29.065 5.368   30.842 1.00 17.63 ?  226  PHE A O    1 
ATOM   3310  C CB   . PHE A 1 260 ? -27.654 7.171   29.244 1.00 15.97 ?  226  PHE A CB   1 
ATOM   3311  C CG   . PHE A 1 260 ? -26.929 8.366   28.633 1.00 16.60 ?  226  PHE A CG   1 
ATOM   3312  C CD1  . PHE A 1 260 ? -27.574 9.496   28.176 1.00 16.23 ?  226  PHE A CD1  1 
ATOM   3313  C CD2  . PHE A 1 260 ? -25.543 8.298   28.532 1.00 14.86 ?  226  PHE A CD2  1 
ATOM   3314  C CE1  . PHE A 1 260 ? -26.825 10.554  27.618 1.00 16.28 ?  226  PHE A CE1  1 
ATOM   3315  C CE2  . PHE A 1 260 ? -24.811 9.348   27.981 1.00 16.63 ?  226  PHE A CE2  1 
ATOM   3316  C CZ   . PHE A 1 260 ? -25.452 10.464  27.525 1.00 16.52 ?  226  PHE A CZ   1 
ATOM   3317  H H    . PHE A 1 260 ? -29.063 8.308   31.097 1.00 20.74 ?  226  PHE A H    1 
ATOM   3318  H HA   . PHE A 1 260 ? -29.592 7.534   28.570 1.00 19.54 ?  226  PHE A HA   1 
ATOM   3319  H HB2  . PHE A 1 260 ? -27.267 7.023   30.121 1.00 19.17 ?  226  PHE A HB2  1 
ATOM   3320  H HB3  . PHE A 1 260 ? -27.477 6.409   28.670 1.00 19.17 ?  226  PHE A HB3  1 
ATOM   3321  H HD1  . PHE A 1 260 ? -28.500 9.561   28.235 1.00 19.48 ?  226  PHE A HD1  1 
ATOM   3322  H HD2  . PHE A 1 260 ? -25.099 7.540   28.836 1.00 17.83 ?  226  PHE A HD2  1 
ATOM   3323  H HE1  . PHE A 1 260 ? -27.260 11.316  27.310 1.00 19.54 ?  226  PHE A HE1  1 
ATOM   3324  H HE2  . PHE A 1 260 ? -23.885 9.289   27.925 1.00 19.96 ?  226  PHE A HE2  1 
ATOM   3325  H HZ   . PHE A 1 260 ? -24.963 11.162  27.153 1.00 19.82 ?  226  PHE A HZ   1 
ATOM   3326  N N    . GLU A 1 261 ? -30.705 5.394   29.305 1.00 18.66 ?  227  GLU A N    1 
ATOM   3327  C CA   . GLU A 1 261 ? -31.233 4.115   29.765 1.00 19.96 ?  227  GLU A CA   1 
ATOM   3328  C C    . GLU A 1 261 ? -30.178 3.024   29.770 1.00 17.99 ?  227  GLU A C    1 
ATOM   3329  O O    . GLU A 1 261 ? -30.196 2.149   30.642 1.00 19.61 ?  227  GLU A O    1 
ATOM   3330  C CB   . GLU A 1 261 ? -32.392 3.681   28.872 1.00 22.31 ?  227  GLU A CB   1 
ATOM   3331  H H    . GLU A 1 261 ? -31.110 5.735   28.628 1.00 22.39 ?  227  GLU A H    1 
ATOM   3332  H HA   . GLU A 1 261 ? -31.554 4.234   30.673 1.00 23.95 ?  227  GLU A HA   1 
ATOM   3333  N N    . GLU A 1 262 ? -29.235 3.045   28.816 1.00 17.96 ?  228  GLU A N    1 
ATOM   3334  C CA   . GLU A 1 262 ? -28.185 2.036   28.772 1.00 20.23 ?  228  GLU A CA   1 
ATOM   3335  C C    . GLU A 1 262 ? -26.796 2.617   29.049 1.00 16.51 ?  228  GLU A C    1 
ATOM   3336  O O    . GLU A 1 262 ? -25.801 1.987   28.699 1.00 16.76 ?  228  GLU A O    1 
ATOM   3337  C CB   . GLU A 1 262 ? -28.195 1.281   27.443 1.00 18.99 ?  228  GLU A CB   1 
ATOM   3338  C CG   . GLU A 1 262 ? -29.553 0.627   27.082 1.00 20.99 ?  228  GLU A CG   1 
ATOM   3339  C CD   . GLU A 1 262 ? -29.527 0.024   25.694 1.00 25.94 ?  228  GLU A CD   1 
ATOM   3340  O OE1  . GLU A 1 262 ? -28.723 -0.914  25.478 1.00 37.70 ?  228  GLU A OE1  1 
ATOM   3341  O OE2  . GLU A 1 262 ? -30.306 0.486   24.816 1.00 32.87 ?  228  GLU A OE2  1 
ATOM   3342  H H    . GLU A 1 262 ? -29.189 3.634   28.191 1.00 21.55 ?  228  GLU A H    1 
ATOM   3343  H HA   . GLU A 1 262 ? -28.375 1.389   29.469 1.00 24.27 ?  228  GLU A HA   1 
ATOM   3344  H HB2  . GLU A 1 262 ? -27.972 1.903   26.733 1.00 22.79 ?  228  GLU A HB2  1 
ATOM   3345  H HB3  . GLU A 1 262 ? -27.532 0.574   27.486 1.00 22.79 ?  228  GLU A HB3  1 
ATOM   3346  H HG2  . GLU A 1 262 ? -29.749 -0.079  27.718 1.00 25.19 ?  228  GLU A HG2  1 
ATOM   3347  H HG3  . GLU A 1 262 ? -30.251 1.300   27.109 1.00 25.19 ?  228  GLU A HG3  1 
ATOM   3348  N N    . ASN A 1 263 ? -26.723 3.775   29.716 1.00 16.38 ?  229  ASN A N    1 
ATOM   3349  C CA   . ASN A 1 263 ? -25.458 4.352   30.180 1.00 15.63 ?  229  ASN A CA   1 
ATOM   3350  C C    . ASN A 1 263 ? -24.456 4.521   29.043 1.00 14.30 ?  229  ASN A C    1 
ATOM   3351  O O    . ASN A 1 263 ? -23.253 4.417   29.266 1.00 14.11 ?  229  ASN A O    1 
ATOM   3352  C CB   . ASN A 1 263 ? -24.929 3.565   31.371 1.00 16.28 ?  229  ASN A CB   1 
ATOM   3353  C CG   . ASN A 1 263 ? -25.767 3.797   32.615 1.00 15.29 ?  229  ASN A CG   1 
ATOM   3354  O OD1  . ASN A 1 263 ? -26.371 4.857   32.762 1.00 15.11 ?  229  ASN A OD1  1 
ATOM   3355  N ND2  . ASN A 1 263 ? -25.826 2.794   33.500 1.00 17.51 ?  229  ASN A ND2  1 
ATOM   3356  H H    . ASN A 1 263 ? -27.408 4.255   29.916 1.00 19.66 ?  229  ASN A H    1 
ATOM   3357  H HA   . ASN A 1 263 ? -25.605 5.258   30.495 1.00 18.76 ?  229  ASN A HA   1 
ATOM   3358  H HB2  . ASN A 1 263 ? -24.949 2.617   31.162 1.00 19.53 ?  229  ASN A HB2  1 
ATOM   3359  H HB3  . ASN A 1 263 ? -24.019 3.843   31.560 1.00 19.53 ?  229  ASN A HB3  1 
ATOM   3360  H HD21 . ASN A 1 263 ? -26.289 2.883   34.219 1.00 21.01 ?  229  ASN A HD21 1 
ATOM   3361  H HD22 . ASN A 1 263 ? -25.400 2.062   33.349 1.00 21.01 ?  229  ASN A HD22 1 
ATOM   3362  N N    . GLY A 1 264 ? -24.956 4.859   27.857 1.00 15.50 ?  230  GLY A N    1 
ATOM   3363  C CA   . GLY A 1 264 ? -24.107 5.180   26.729 1.00 17.07 ?  230  GLY A CA   1 
ATOM   3364  C C    . GLY A 1 264 ? -23.997 4.091   25.685 1.00 15.48 ?  230  GLY A C    1 
ATOM   3365  O O    . GLY A 1 264 ? -23.624 4.388   24.550 1.00 15.32 ?  230  GLY A O    1 
ATOM   3366  H H    . GLY A 1 264 ? -25.797 4.909   27.686 1.00 18.60 ?  230  GLY A H    1 
ATOM   3367  H HA2  . GLY A 1 264 ? -24.456 5.973   26.293 1.00 20.49 ?  230  GLY A HA2  1 
ATOM   3368  H HA3  . GLY A 1 264 ? -23.213 5.367   27.056 1.00 20.49 ?  230  GLY A HA3  1 
ATOM   3369  N N    . LEU A 1 265 ? -24.335 2.841   26.034 1.00 17.20 ?  231  LEU A N    1 
ATOM   3370  C CA   . LEU A 1 265 ? -24.275 1.748   25.063 1.00 16.97 ?  231  LEU A CA   1 
ATOM   3371  C C    . LEU A 1 265 ? -25.182 2.005   23.879 1.00 18.51 ?  231  LEU A C    1 
ATOM   3372  O O    . LEU A 1 265 ? -24.899 1.555   22.760 1.00 20.12 ?  231  LEU A O    1 
ATOM   3373  C CB   . LEU A 1 265 ? -24.728 0.446   25.710 1.00 19.02 ?  231  LEU A CB   1 
ATOM   3374  C CG   . LEU A 1 265 ? -23.853 -0.138  26.788 1.00 25.41 ?  231  LEU A CG   1 
ATOM   3375  C CD1  . LEU A 1 265 ? -24.403 -1.487  27.243 1.00 28.23 ?  231  LEU A CD1  1 
ATOM   3376  C CD2  . LEU A 1 265 ? -22.441 -0.282  26.308 1.00 25.43 ?  231  LEU A CD2  1 
ATOM   3377  H H    . LEU A 1 265 ? -24.599 2.605   26.817 1.00 20.64 ?  231  LEU A H    1 
ATOM   3378  H HA   . LEU A 1 265 ? -23.355 1.667   24.766 1.00 20.36 ?  231  LEU A HA   1 
ATOM   3379  H HB2  . LEU A 1 265 ? -25.599 0.600   26.108 1.00 22.82 ?  231  LEU A HB2  1 
ATOM   3380  H HB3  . LEU A 1 265 ? -24.796 -0.224  25.011 1.00 22.82 ?  231  LEU A HB3  1 
ATOM   3381  H HG   . LEU A 1 265 ? -23.849 0.463   27.549 1.00 30.49 ?  231  LEU A HG   1 
ATOM   3382  H HD11 . LEU A 1 265 ? -23.783 -1.883  27.875 1.00 33.87 ?  231  LEU A HD11 1 
ATOM   3383  H HD12 . LEU A 1 265 ? -25.264 -1.350  27.666 1.00 33.87 ?  231  LEU A HD12 1 
ATOM   3384  H HD13 . LEU A 1 265 ? -24.502 -2.064  26.470 1.00 33.87 ?  231  LEU A HD13 1 
ATOM   3385  H HD21 . LEU A 1 265 ? -21.941 -0.808  26.952 1.00 30.52 ?  231  LEU A HD21 1 
ATOM   3386  H HD22 . LEU A 1 265 ? -22.443 -0.728  25.447 1.00 30.52 ?  231  LEU A HD22 1 
ATOM   3387  H HD23 . LEU A 1 265 ? -22.045 0.600   26.223 1.00 30.52 ?  231  LEU A HD23 1 
ATOM   3388  N N    . GLU A 1 266 ? -26.270 2.705   24.096 1.00 15.63 ?  232  GLU A N    1 
ATOM   3389  C CA   . GLU A 1 266 ? -27.210 2.965   23.022 1.00 16.54 ?  232  GLU A CA   1 
ATOM   3390  C C    . GLU A 1 266 ? -26.660 3.909   21.975 1.00 15.41 ?  232  GLU A C    1 
ATOM   3391  O O    . GLU A 1 266 ? -27.259 4.069   20.926 1.00 18.21 ?  232  GLU A O    1 
ATOM   3392  C CB   . GLU A 1 266 ? -28.540 3.499   23.578 1.00 18.78 ?  232  GLU A CB   1 
ATOM   3393  C CG   . GLU A 1 266 ? -28.457 4.859   24.321 1.00 16.92 ?  232  GLU A CG   1 
ATOM   3394  C CD   . GLU A 1 266 ? -28.232 4.676   25.815 1.00 17.23 ?  232  GLU A CD   1 
ATOM   3395  O OE1  . GLU A 1 266 ? -27.169 4.252   26.240 1.00 17.84 ?  232  GLU A OE1  1 
ATOM   3396  O OE2  . GLU A 1 266 ? -29.161 4.971   26.606 1.00 20.98 ?  232  GLU A OE2  1 
ATOM   3397  H H    . GLU A 1 266 ? -26.493 3.042   24.855 1.00 18.75 ?  232  GLU A H    1 
ATOM   3398  H HA   . GLU A 1 266 ? -27.406 2.124   22.581 1.00 19.85 ?  232  GLU A HA   1 
ATOM   3399  H HB2  . GLU A 1 266 ? -29.157 3.612   22.838 1.00 22.53 ?  232  GLU A HB2  1 
ATOM   3400  H HB3  . GLU A 1 266 ? -28.890 2.849   24.207 1.00 22.53 ?  232  GLU A HB3  1 
ATOM   3401  H HG2  . GLU A 1 266 ? -27.717 5.374   23.963 1.00 20.30 ?  232  GLU A HG2  1 
ATOM   3402  H HG3  . GLU A 1 266 ? -29.289 5.343   24.196 1.00 20.30 ?  232  GLU A HG3  1 
ATOM   3403  N N    . TYR A 1 267 ? -25.537 4.577   22.270 1.00 15.41 ?  233  TYR A N    1 
ATOM   3404  C CA   . TYR A 1 267 ? -24.953 5.576   21.412 1.00 17.15 ?  233  TYR A CA   1 
ATOM   3405  C C    . TYR A 1 267 ? -23.656 5.108   20.787 1.00 18.22 ?  233  TYR A C    1 
ATOM   3406  O O    . TYR A 1 267 ? -22.993 5.913   20.136 1.00 21.64 ?  233  TYR A O    1 
ATOM   3407  C CB   . TYR A 1 267 ? -24.689 6.853   22.222 1.00 18.69 ?  233  TYR A CB   1 
ATOM   3408  C CG   . TYR A 1 267 ? -25.907 7.496   22.818 1.00 16.95 ?  233  TYR A CG   1 
ATOM   3409  C CD1  . TYR A 1 267 ? -26.933 7.914   22.009 1.00 15.55 ?  233  TYR A CD1  1 
ATOM   3410  C CD2  . TYR A 1 267 ? -26.023 7.714   24.190 1.00 19.26 ?  233  TYR A CD2  1 
ATOM   3411  C CE1  . TYR A 1 267 ? -28.050 8.518   22.522 1.00 19.61 ?  233  TYR A CE1  1 
ATOM   3412  C CE2  . TYR A 1 267 ? -27.109 8.317   24.720 1.00 20.45 ?  233  TYR A CE2  1 
ATOM   3413  C CZ   . TYR A 1 267 ? -28.137 8.714   23.896 1.00 21.36 ?  233  TYR A CZ   1 
ATOM   3414  O OH   . TYR A 1 267 ? -29.271 9.336   24.425 1.00 24.91 ?  233  TYR A OH   1 
ATOM   3415  H H    . TYR A 1 267 ? -25.089 4.454   22.994 1.00 18.50 ?  233  TYR A H    1 
ATOM   3416  H HA   . TYR A 1 267 ? -25.578 5.779   20.698 1.00 20.59 ?  233  TYR A HA   1 
ATOM   3417  H HB2  . TYR A 1 267 ? -24.090 6.634   22.953 1.00 22.42 ?  233  TYR A HB2  1 
ATOM   3418  H HB3  . TYR A 1 267 ? -24.274 7.506   21.637 1.00 22.42 ?  233  TYR A HB3  1 
ATOM   3419  H HD1  . TYR A 1 267 ? -26.869 7.785   21.090 1.00 18.67 ?  233  TYR A HD1  1 
ATOM   3420  H HD2  . TYR A 1 267 ? -25.336 7.438   24.753 1.00 23.11 ?  233  TYR A HD2  1 
ATOM   3421  H HE1  . TYR A 1 267 ? -28.739 8.792   21.961 1.00 23.53 ?  233  TYR A HE1  1 
ATOM   3422  H HE2  . TYR A 1 267 ? -27.162 8.464   25.637 1.00 24.55 ?  233  TYR A HE2  1 
ATOM   3423  H HH   . TYR A 1 267 ? -29.802 9.539   23.807 1.00 29.89 ?  233  TYR A HH   1 
ATOM   3424  N N    . LEU A 1 268 ? -23.280 3.853   20.951 1.00 14.77 ?  234  LEU A N    1 
ATOM   3425  C CA   . LEU A 1 268 ? -22.014 3.364   20.455 1.00 17.16 ?  234  LEU A CA   1 
ATOM   3426  C C    . LEU A 1 268 ? -22.041 3.027   18.971 1.00 18.15 ?  234  LEU A C    1 
ATOM   3427  O O    . LEU A 1 268 ? -20.987 2.652   18.440 1.00 17.27 ?  234  LEU A O    1 
ATOM   3428  C CB   . LEU A 1 268 ? -21.595 2.131   21.237 1.00 20.02 ?  234  LEU A CB   1 
ATOM   3429  C CG   . LEU A 1 268 ? -20.765 2.325   22.484 1.00 33.47 ?  234  LEU A CG   1 
ATOM   3430  C CD1  . LEU A 1 268 ? -20.603 0.989   23.195 1.00 27.78 ?  234  LEU A CD1  1 
ATOM   3431  C CD2  . LEU A 1 268 ? -19.384 2.902   22.131 1.00 24.56 ?  234  LEU A CD2  1 
ATOM   3432  H H    . LEU A 1 268 ? -23.751 3.256   21.354 1.00 17.72 ?  234  LEU A H    1 
ATOM   3433  H HA   . LEU A 1 268 ? -21.347 4.056   20.591 1.00 20.60 ?  234  LEU A HA   1 
ATOM   3434  H HB2  . LEU A 1 268 ? -22.403 1.669   21.510 1.00 24.02 ?  234  LEU A HB2  1 
ATOM   3435  H HB3  . LEU A 1 268 ? -21.076 1.569   20.642 1.00 24.02 ?  234  LEU A HB3  1 
ATOM   3436  H HG   . LEU A 1 268 ? -21.210 2.951   23.075 1.00 40.16 ?  234  LEU A HG   1 
ATOM   3437  H HD11 . LEU A 1 268 ? -20.057 1.117   23.987 1.00 33.34 ?  234  LEU A HD11 1 
ATOM   3438  H HD12 . LEU A 1 268 ? -21.478 0.657   23.447 1.00 33.34 ?  234  LEU A HD12 1 
ATOM   3439  H HD13 . LEU A 1 268 ? -20.171 0.362   22.594 1.00 33.34 ?  234  LEU A HD13 1 
ATOM   3440  H HD21 . LEU A 1 268 ? -18.853 2.968   22.940 1.00 29.47 ?  234  LEU A HD21 1 
ATOM   3441  H HD22 . LEU A 1 268 ? -18.948 2.313   21.496 1.00 29.47 ?  234  LEU A HD22 1 
ATOM   3442  H HD23 . LEU A 1 268 ? -19.500 3.783   21.740 1.00 29.47 ?  234  LEU A HD23 1 
ATOM   3443  N N    . GLY A 1 269 ? -23.186 3.178   18.294 1.00 21.61 ?  235  GLY A N    1 
ATOM   3444  C CA   . GLY A 1 269 ? -23.293 2.636   16.948 1.00 23.86 ?  235  GLY A CA   1 
ATOM   3445  C C    . GLY A 1 269 ? -22.394 3.325   15.964 1.00 19.86 ?  235  GLY A C    1 
ATOM   3446  O O    . GLY A 1 269 ? -22.014 2.739   14.930 1.00 17.57 ?  235  GLY A O    1 
ATOM   3447  H H    . GLY A 1 269 ? -23.889 3.578   18.587 1.00 25.93 ?  235  GLY A H    1 
ATOM   3448  H HA2  . GLY A 1 269 ? -23.060 1.694   16.965 1.00 28.63 ?  235  GLY A HA2  1 
ATOM   3449  H HA3  . GLY A 1 269 ? -24.208 2.728   16.640 1.00 28.63 ?  235  GLY A HA3  1 
ATOM   3450  N N    . TYR A 1 270 ? -22.008 4.555   16.263 1.00 16.94 ?  236  TYR A N    1 
ATOM   3451  C CA   . TYR A 1 270 ? -21.175 5.300   15.354 1.00 15.47 ?  236  TYR A CA   1 
ATOM   3452  C C    . TYR A 1 270 ? -19.696 4.986   15.534 1.00 13.38 ?  236  TYR A C    1 
ATOM   3453  O O    . TYR A 1 270 ? -18.907 5.400   14.698 1.00 16.12 ?  236  TYR A O    1 
ATOM   3454  C CB   . TYR A 1 270 ? -21.304 6.830   15.527 1.00 18.44 ?  236  TYR A CB   1 
ATOM   3455  C CG   . TYR A 1 270 ? -22.687 7.358   15.280 1.00 21.51 ?  236  TYR A CG   1 
ATOM   3456  C CD1  . TYR A 1 270 ? -23.211 7.452   14.007 1.00 19.05 ?  236  TYR A CD1  1 
ATOM   3457  C CD2  . TYR A 1 270 ? -23.443 7.783   16.333 1.00 22.22 ?  236  TYR A CD2  1 
ATOM   3458  C CE1  . TYR A 1 270 ? -24.494 7.946   13.803 1.00 21.01 ?  236  TYR A CE1  1 
ATOM   3459  C CE2  . TYR A 1 270 ? -24.693 8.299   16.144 1.00 22.78 ?  236  TYR A CE2  1 
ATOM   3460  C CZ   . TYR A 1 270 ? -25.218 8.355   14.879 1.00 23.38 ?  236  TYR A CZ   1 
ATOM   3461  O OH   . TYR A 1 270 ? -26.500 8.879   14.702 1.00 23.01 ?  236  TYR A OH   1 
ATOM   3462  H H    . TYR A 1 270 ? -22.218 4.974   16.984 1.00 20.32 ?  236  TYR A H    1 
ATOM   3463  H HA   . TYR A 1 270 ? -21.487 5.069   14.465 1.00 18.56 ?  236  TYR A HA   1 
ATOM   3464  H HB2  . TYR A 1 270 ? -21.057 7.061   16.436 1.00 22.13 ?  236  TYR A HB2  1 
ATOM   3465  H HB3  . TYR A 1 270 ? -20.705 7.265   14.900 1.00 22.13 ?  236  TYR A HB3  1 
ATOM   3466  H HD1  . TYR A 1 270 ? -22.701 7.181   13.278 1.00 22.86 ?  236  TYR A HD1  1 
ATOM   3467  H HD2  . TYR A 1 270 ? -23.101 7.721   17.196 1.00 26.66 ?  236  TYR A HD2  1 
ATOM   3468  H HE1  . TYR A 1 270 ? -24.851 7.996   12.945 1.00 25.21 ?  236  TYR A HE1  1 
ATOM   3469  H HE2  . TYR A 1 270 ? -25.186 8.610   16.869 1.00 27.34 ?  236  TYR A HE2  1 
ATOM   3470  H HH   . TYR A 1 270 ? -26.688 8.909   13.883 1.00 27.62 ?  236  TYR A HH   1 
ATOM   3471  N N    . PHE A 1 271 ? -19.309 4.286   16.591 1.00 11.93 ?  237  PHE A N    1 
ATOM   3472  C CA   . PHE A 1 271 ? -17.927 4.325   17.073 1.00 11.35 ?  237  PHE A CA   1 
ATOM   3473  C C    . PHE A 1 271 ? -17.306 2.936   17.162 1.00 12.34 ?  237  PHE A C    1 
ATOM   3474  O O    . PHE A 1 271 ? -17.986 1.936   17.400 1.00 13.56 ?  237  PHE A O    1 
ATOM   3475  C CB   . PHE A 1 271 ? -17.900 4.996   18.433 1.00 12.73 ?  237  PHE A CB   1 
ATOM   3476  C CG   . PHE A 1 271 ? -18.569 6.346   18.453 1.00 11.69 ?  237  PHE A CG   1 
ATOM   3477  C CD1  . PHE A 1 271 ? -18.107 7.344   17.639 1.00 12.92 ?  237  PHE A CD1  1 
ATOM   3478  C CD2  . PHE A 1 271 ? -19.663 6.592   19.227 1.00 13.92 ?  237  PHE A CD2  1 
ATOM   3479  C CE1  . PHE A 1 271 ? -18.690 8.576   17.629 1.00 15.08 ?  237  PHE A CE1  1 
ATOM   3480  C CE2  . PHE A 1 271 ? -20.281 7.858   19.209 1.00 13.56 ?  237  PHE A CE2  1 
ATOM   3481  C CZ   . PHE A 1 271 ? -19.776 8.807   18.426 1.00 14.56 ?  237  PHE A CZ   1 
ATOM   3482  H H    . PHE A 1 271 ? -19.828 3.777   17.051 1.00 14.31 ?  237  PHE A H    1 
ATOM   3483  H HA   . PHE A 1 271 ? -17.376 4.814   16.442 1.00 13.62 ?  237  PHE A HA   1 
ATOM   3484  H HB2  . PHE A 1 271 ? -18.358 4.428   19.072 1.00 15.27 ?  237  PHE A HB2  1 
ATOM   3485  H HB3  . PHE A 1 271 ? -16.976 5.119   18.703 1.00 15.27 ?  237  PHE A HB3  1 
ATOM   3486  H HD1  . PHE A 1 271 ? -17.382 7.179   17.081 1.00 15.50 ?  237  PHE A HD1  1 
ATOM   3487  H HD2  . PHE A 1 271 ? -20.004 5.919   19.771 1.00 16.71 ?  237  PHE A HD2  1 
ATOM   3488  H HE1  . PHE A 1 271 ? -18.353 9.252   17.087 1.00 18.10 ?  237  PHE A HE1  1 
ATOM   3489  H HE2  . PHE A 1 271 ? -21.029 8.027   19.735 1.00 16.27 ?  237  PHE A HE2  1 
ATOM   3490  H HZ   . PHE A 1 271 ? -20.171 9.649   18.421 1.00 17.47 ?  237  PHE A HZ   1 
ATOM   3491  N N    . ASN A 1 272 ? -15.975 2.869   16.987 1.00 12.63 ?  238  ASN A N    1 
ATOM   3492  C CA   . ASN A 1 272 ? -15.266 1.628   17.245 1.00 12.00 ?  238  ASN A CA   1 
ATOM   3493  C C    . ASN A 1 272 ? -15.108 1.342   18.726 1.00 12.65 ?  238  ASN A C    1 
ATOM   3494  O O    . ASN A 1 272 ? -14.747 0.208   19.094 1.00 12.48 ?  238  ASN A O    1 
ATOM   3495  C CB   . ASN A 1 272 ? -13.901 1.646   16.548 1.00 11.32 ?  238  ASN A CB   1 
ATOM   3496  C CG   . ASN A 1 272 ? -14.017 1.841   15.064 1.00 12.64 ?  238  ASN A CG   1 
ATOM   3497  O OD1  . ASN A 1 272 ? -13.721 2.890   14.509 1.00 13.94 ?  238  ASN A OD1  1 
ATOM   3498  N ND2  . ASN A 1 272 ? -14.495 0.812   14.386 1.00 14.54 ?  238  ASN A ND2  1 
ATOM   3499  H H    . ASN A 1 272 ? -15.479 3.521   16.724 1.00 15.16 ?  238  ASN A H    1 
ATOM   3500  H HA   . ASN A 1 272 ? -15.777 0.896   16.866 1.00 14.40 ?  238  ASN A HA   1 
ATOM   3501  H HB2  . ASN A 1 272 ? -13.371 2.374   16.907 1.00 13.59 ?  238  ASN A HB2  1 
ATOM   3502  H HB3  . ASN A 1 272 ? -13.453 0.800   16.707 1.00 13.59 ?  238  ASN A HB3  1 
ATOM   3503  H HD21 . ASN A 1 272 ? -14.585 0.863   13.533 1.00 17.45 ?  238  ASN A HD21 1 
ATOM   3504  H HD22 . ASN A 1 272 ? -14.716 0.091   14.799 1.00 17.45 ?  238  ASN A HD22 1 
ATOM   3505  N N    . GLY A 1 273 ? -15.321 2.332   19.588 1.00 12.23 ?  239  GLY A N    1 
ATOM   3506  C CA   . GLY A 1 273 ? -15.210 2.077   21.008 1.00 12.77 ?  239  GLY A CA   1 
ATOM   3507  C C    . GLY A 1 273 ? -15.446 3.343   21.806 1.00 10.82 ?  239  GLY A C    1 
ATOM   3508  O O    . GLY A 1 273 ? -15.743 4.404   21.255 1.00 11.24 ?  239  GLY A O    1 
ATOM   3509  H H    . GLY A 1 273 ? -15.527 3.140   19.375 1.00 14.68 ?  239  GLY A H    1 
ATOM   3510  H HA2  . GLY A 1 273 ? -15.866 1.414   21.274 1.00 15.33 ?  239  GLY A HA2  1 
ATOM   3511  H HA3  . GLY A 1 273 ? -14.323 1.742   21.212 1.00 15.33 ?  239  GLY A HA3  1 
ATOM   3512  N N    . SER A 1 274 ? -15.315 3.173   23.136 1.00 11.39 ?  240  SER A N    1 
ATOM   3513  C CA   . SER A 1 274 ? -15.471 4.292   24.053 1.00 10.59 ?  240  SER A CA   1 
ATOM   3514  C C    . SER A 1 274 ? -14.265 4.450   24.943 1.00 10.74 ?  240  SER A C    1 
ATOM   3515  O O    . SER A 1 274 ? -13.689 3.472   25.436 1.00 11.82 ?  240  SER A O    1 
ATOM   3516  C CB   . SER A 1 274 ? -16.697 4.081   24.962 1.00 11.48 ?  240  SER A CB   1 
ATOM   3517  O OG   . SER A 1 274 ? -16.998 5.247   25.723 1.00 12.27 ?  240  SER A OG   1 
ATOM   3518  H H    . SER A 1 274 ? -15.138 2.422   23.516 1.00 13.67 ?  240  SER A H    1 
ATOM   3519  H HA   . SER A 1 274 ? -15.566 5.100   23.524 1.00 12.71 ?  240  SER A HA   1 
ATOM   3520  H HB2  . SER A 1 274 ? -17.463 3.864   24.407 1.00 13.78 ?  240  SER A HB2  1 
ATOM   3521  H HB3  . SER A 1 274 ? -16.511 3.350   25.571 1.00 13.78 ?  240  SER A HB3  1 
ATOM   3522  H HG   . SER A 1 274 ? -16.328 5.477   26.175 1.00 14.73 ?  240  SER A HG   1 
ATOM   3523  N N    . TYR A 1 275 ? -13.940 5.721   25.192 1.00 10.82 ?  241  TYR A N    1 
ATOM   3524  C CA   . TYR A 1 275 ? -13.166 6.164   26.336 1.00 11.29 ?  241  TYR A CA   1 
ATOM   3525  C C    . TYR A 1 275 ? -14.088 6.317   27.536 1.00 11.10 ?  241  TYR A C    1 
ATOM   3526  O O    . TYR A 1 275 ? -15.278 6.612   27.388 1.00 11.80 ?  241  TYR A O    1 
ATOM   3527  C CB   . TYR A 1 275 ? -12.484 7.451   25.934 1.00 12.19 ?  241  TYR A CB   1 
ATOM   3528  C CG   . TYR A 1 275 ? -12.022 8.418   27.017 1.00 10.63 ?  241  TYR A CG   1 
ATOM   3529  C CD1  . TYR A 1 275 ? -12.945 9.229   27.667 1.00 10.45 ?  241  TYR A CD1  1 
ATOM   3530  C CD2  . TYR A 1 275 ? -10.691 8.578   27.331 1.00 10.62 ?  241  TYR A CD2  1 
ATOM   3531  C CE1  . TYR A 1 275 ? -12.534 10.186  28.580 1.00 10.94 ?  241  TYR A CE1  1 
ATOM   3532  C CE2  . TYR A 1 275 ? -10.263 9.558   28.249 1.00 11.15 ?  241  TYR A CE2  1 
ATOM   3533  C CZ   . TYR A 1 275 ? -11.209 10.316  28.879 1.00 10.89 ?  241  TYR A CZ   1 
ATOM   3534  O OH   . TYR A 1 275 ? -10.789 11.250  29.808 1.00 11.31 ?  241  TYR A OH   1 
ATOM   3535  H H    . TYR A 1 275 ? -14.171 6.375   24.683 1.00 12.98 ?  241  TYR A H    1 
ATOM   3536  H HA   . TYR A 1 275 ? -12.478 5.537   26.612 1.00 13.54 ?  241  TYR A HA   1 
ATOM   3537  H HB2  . TYR A 1 275 ? -11.693 7.215   25.425 1.00 14.62 ?  241  TYR A HB2  1 
ATOM   3538  H HB3  . TYR A 1 275 ? -13.104 7.945   25.374 1.00 14.62 ?  241  TYR A HB3  1 
ATOM   3539  H HD1  . TYR A 1 275 ? -13.852 9.127   27.487 1.00 12.54 ?  241  TYR A HD1  1 
ATOM   3540  H HD2  . TYR A 1 275 ? -10.060 8.026   26.929 1.00 12.74 ?  241  TYR A HD2  1 
ATOM   3541  H HE1  . TYR A 1 275 ? -13.160 10.739  28.988 1.00 13.12 ?  241  TYR A HE1  1 
ATOM   3542  H HE2  . TYR A 1 275 ? -9.359  9.687   28.421 1.00 13.38 ?  241  TYR A HE2  1 
ATOM   3543  H HH   . TYR A 1 275 ? -11.444 11.522  30.259 1.00 13.57 ?  241  TYR A HH   1 
ATOM   3544  N N    . LEU A 1 276 ? -13.540 6.058   28.722 1.00 10.79 ?  242  LEU A N    1 
ATOM   3545  C CA   . LEU A 1 276 ? -14.285 6.200   29.970 1.00 11.36 ?  242  LEU A CA   1 
ATOM   3546  C C    . LEU A 1 276 ? -13.576 7.181   30.883 1.00 10.77 ?  242  LEU A C    1 
ATOM   3547  O O    . LEU A 1 276 ? -12.382 7.034   31.154 1.00 11.55 ?  242  LEU A O    1 
ATOM   3548  C CB   . LEU A 1 276 ? -14.368 4.858   30.739 1.00 13.11 ?  242  LEU A CB   1 
ATOM   3549  C CG   . LEU A 1 276 ? -14.779 3.636   29.955 1.00 13.61 ?  242  LEU A CG   1 
ATOM   3550  C CD1  . LEU A 1 276 ? -14.627 2.398   30.788 1.00 13.91 ?  242  LEU A CD1  1 
ATOM   3551  C CD2  . LEU A 1 276 ? -16.188 3.790   29.498 1.00 19.13 ?  242  LEU A CD2  1 
ATOM   3552  H H    . LEU A 1 276 ? -12.728 5.795   28.829 1.00 12.95 ?  242  LEU A H    1 
ATOM   3553  H HA   . LEU A 1 276 ? -15.173 6.521   29.747 1.00 13.63 ?  242  LEU A HA   1 
ATOM   3554  H HB2  . LEU A 1 276 ? -13.491 4.673   31.110 1.00 15.73 ?  242  LEU A HB2  1 
ATOM   3555  H HB3  . LEU A 1 276 ? -15.015 4.965   31.454 1.00 15.73 ?  242  LEU A HB3  1 
ATOM   3556  H HG   . LEU A 1 276 ? -14.206 3.539   29.178 1.00 16.33 ?  242  LEU A HG   1 
ATOM   3557  H HD11 . LEU A 1 276 ? -14.979 1.640   30.294 1.00 16.69 ?  242  LEU A HD11 1 
ATOM   3558  H HD12 . LEU A 1 276 ? -13.686 2.259   30.979 1.00 16.69 ?  242  LEU A HD12 1 
ATOM   3559  H HD13 . LEU A 1 276 ? -15.120 2.511   31.615 1.00 16.69 ?  242  LEU A HD13 1 
ATOM   3560  H HD21 . LEU A 1 276 ? -16.420 3.038   28.930 1.00 22.96 ?  242  LEU A HD21 1 
ATOM   3561  H HD22 . LEU A 1 276 ? -16.771 3.811   30.273 1.00 22.96 ?  242  LEU A HD22 1 
ATOM   3562  H HD23 . LEU A 1 276 ? -16.270 4.618   29.000 1.00 22.96 ?  242  LEU A HD23 1 
ATOM   3563  N N    . GLU A 1 277 ? -14.343 8.151   31.390 1.00 11.54 ?  243  GLU A N    1 
ATOM   3564  C CA   . GLU A 1 277 ? -13.929 9.028   32.479 1.00 10.97 ?  243  GLU A CA   1 
ATOM   3565  C C    . GLU A 1 277 ? -15.097 9.207   33.441 1.00 12.24 ?  243  GLU A C    1 
ATOM   3566  O O    . GLU A 1 277 ? -16.220 8.765   33.201 1.00 12.93 ?  243  GLU A O    1 
ATOM   3567  C CB   . GLU A 1 277 ? -13.372 10.384  32.010 1.00 11.80 ?  243  GLU A CB   1 
ATOM   3568  C CG   . GLU A 1 277 ? -14.469 11.250  31.392 1.00 11.24 ?  243  GLU A CG   1 
ATOM   3569  C CD   . GLU A 1 277 ? -13.951 12.580  30.864 1.00 11.04 ?  243  GLU A CD   1 
ATOM   3570  O OE1  . GLU A 1 277 ? -12.688 12.767  30.845 1.00 12.50 ?  243  GLU A OE1  1 
ATOM   3571  O OE2  . GLU A 1 277 ? -14.793 13.415  30.461 1.00 11.51 ?  243  GLU A OE2  1 
ATOM   3572  H H    . GLU A 1 277 ? -15.136 8.324   31.106 1.00 13.84 ?  243  GLU A H    1 
ATOM   3573  H HA   . GLU A 1 277 ? -13.203 8.592   32.953 1.00 13.16 ?  243  GLU A HA   1 
ATOM   3574  H HB2  . GLU A 1 277 ? -12.999 10.858  32.770 1.00 14.16 ?  243  GLU A HB2  1 
ATOM   3575  H HB3  . GLU A 1 277 ? -12.685 10.235  31.342 1.00 14.16 ?  243  GLU A HB3  1 
ATOM   3576  H HG2  . GLU A 1 277 ? -14.870 10.769  30.651 1.00 13.49 ?  243  GLU A HG2  1 
ATOM   3577  H HG3  . GLU A 1 277 ? -15.140 11.437  32.067 1.00 13.49 ?  243  GLU A HG3  1 
ATOM   3578  N N    . GLY A 1 278 ? -14.812 9.821   34.576 1.00 12.45 ?  244  GLY A N    1 
ATOM   3579  C CA   . GLY A 1 278 ? -15.804 9.908   35.643 1.00 15.08 ?  244  GLY A CA   1 
ATOM   3580  C C    . GLY A 1 278 ? -16.241 8.548   36.153 1.00 15.49 ?  244  GLY A C    1 
ATOM   3581  O O    . GLY A 1 278 ? -17.325 8.434   36.738 1.00 16.79 ?  244  GLY A O    1 
ATOM   3582  H H    . GLY A 1 278 ? -14.058 10.194  34.756 1.00 14.93 ?  244  GLY A H    1 
ATOM   3583  H HA2  . GLY A 1 278 ? -15.430 10.406  36.387 1.00 18.10 ?  244  GLY A HA2  1 
ATOM   3584  H HA3  . GLY A 1 278 ? -16.587 10.375  35.313 1.00 18.10 ?  244  GLY A HA3  1 
ATOM   3585  N N    . PHE A 1 279 ? -15.414 7.519   35.955 1.00 13.44 ?  245  PHE A N    1 
ATOM   3586  C CA   . PHE A 1 279 ? -15.882 6.148   36.114 1.00 14.77 ?  245  PHE A CA   1 
ATOM   3587  C C    . PHE A 1 279 ? -16.100 5.795   37.567 1.00 18.23 ?  245  PHE A C    1 
ATOM   3588  O O    . PHE A 1 279 ? -16.990 4.982   37.888 1.00 16.16 ?  245  PHE A O    1 
ATOM   3589  C CB   . PHE A 1 279 ? -14.900 5.206   35.439 1.00 15.29 ?  245  PHE A CB   1 
ATOM   3590  C CG   . PHE A 1 279 ? -15.474 3.833   35.185 1.00 14.57 ?  245  PHE A CG   1 
ATOM   3591  C CD1  . PHE A 1 279 ? -16.463 3.657   34.251 1.00 14.29 ?  245  PHE A CD1  1 
ATOM   3592  C CD2  . PHE A 1 279 ? -15.016 2.729   35.898 1.00 15.67 ?  245  PHE A CD2  1 
ATOM   3593  C CE1  . PHE A 1 279 ? -16.989 2.372   34.006 1.00 12.89 ?  245  PHE A CE1  1 
ATOM   3594  C CE2  . PHE A 1 279 ? -15.519 1.463   35.643 1.00 14.32 ?  245  PHE A CE2  1 
ATOM   3595  C CZ   . PHE A 1 279 ? -16.524 1.297   34.714 1.00 15.64 ?  245  PHE A CZ   1 
ATOM   3596  H H    . PHE A 1 279 ? -14.587 7.590   35.730 1.00 16.12 ?  245  PHE A H    1 
ATOM   3597  H HA   . PHE A 1 279 ? -16.740 6.038   35.675 1.00 17.73 ?  245  PHE A HA   1 
ATOM   3598  H HB2  . PHE A 1 279 ? -14.639 5.584   34.584 1.00 18.35 ?  245  PHE A HB2  1 
ATOM   3599  H HB3  . PHE A 1 279 ? -14.121 5.104   36.008 1.00 18.35 ?  245  PHE A HB3  1 
ATOM   3600  H HD1  . PHE A 1 279 ? -16.789 4.388   33.778 1.00 17.15 ?  245  PHE A HD1  1 
ATOM   3601  H HD2  . PHE A 1 279 ? -14.366 2.842   36.553 1.00 18.81 ?  245  PHE A HD2  1 
ATOM   3602  H HE1  . PHE A 1 279 ? -17.652 2.255   33.363 1.00 15.47 ?  245  PHE A HE1  1 
ATOM   3603  H HE2  . PHE A 1 279 ? -15.180 0.726   36.099 1.00 17.18 ?  245  PHE A HE2  1 
ATOM   3604  H HZ   . PHE A 1 279 ? -16.886 0.453   34.567 1.00 18.77 ?  245  PHE A HZ   1 
ATOM   3605  N N    . ASP A 1 280 ? -15.305 6.391   38.456 1.00 16.26 ?  246  ASP A N    1 
ATOM   3606  C CA   . ASP A 1 280 ? -15.426 6.174   39.898 1.00 17.07 ?  246  ASP A CA   1 
ATOM   3607  C C    . ASP A 1 280 ? -15.905 7.406   40.638 1.00 17.87 ?  246  ASP A C    1 
ATOM   3608  O O    . ASP A 1 280 ? -15.717 7.480   41.866 1.00 21.49 ?  246  ASP A O    1 
ATOM   3609  C CB   . ASP A 1 280 ? -14.124 5.624   40.475 1.00 17.55 ?  246  ASP A CB   1 
ATOM   3610  C CG   . ASP A 1 280 ? -12.953 6.550   40.323 1.00 20.97 ?  246  ASP A CG   1 
ATOM   3611  O OD1  . ASP A 1 280 ? -13.062 7.550   39.604 1.00 18.85 ?  246  ASP A OD1  1 
ATOM   3612  O OD2  . ASP A 1 280 ? -11.903 6.233   40.934 1.00 24.54 ?  246  ASP A OD2  1 
ATOM   3613  H H    . ASP A 1 280 ? -14.675 6.937   38.244 1.00 19.52 ?  246  ASP A H    1 
ATOM   3614  H HA   . ASP A 1 280 ? -16.099 5.492   40.048 1.00 20.49 ?  246  ASP A HA   1 
ATOM   3615  H HB2  . ASP A 1 280 ? -14.248 5.458   41.422 1.00 21.06 ?  246  ASP A HB2  1 
ATOM   3616  H HB3  . ASP A 1 280 ? -13.906 4.796   40.019 1.00 21.06 ?  246  ASP A HB3  1 
ATOM   3617  N N    . SER A 1 281 ? -16.541 8.346   39.959 1.00 18.64 ?  247  SER A N    1 
ATOM   3618  C CA   . SER A 1 281 ? -16.971 9.617   40.541 1.00 19.24 ?  247  SER A CA   1 
ATOM   3619  C C    . SER A 1 281 ? -18.497 9.634   40.562 1.00 18.12 ?  247  SER A C    1 
ATOM   3620  O O    . SER A 1 281 ? -19.149 10.055  39.614 1.00 18.56 ?  247  SER A O    1 
ATOM   3621  C CB   . SER A 1 281 ? -16.427 10.798  39.737 1.00 27.53 ?  247  SER A CB   1 
ATOM   3622  O OG   . SER A 1 281 ? -15.083 10.575  39.369 1.00 40.44 ?  247  SER A OG   1 
ATOM   3623  H H    . SER A 1 281 ? -16.744 8.273   39.126 1.00 22.37 ?  247  SER A H    1 
ATOM   3624  H HA   . SER A 1 281 ? -16.642 9.674   41.452 1.00 23.08 ?  247  SER A HA   1 
ATOM   3625  H HB2  . SER A 1 281 ? -16.961 10.906  38.934 1.00 33.03 ?  247  SER A HB2  1 
ATOM   3626  H HB3  . SER A 1 281 ? -16.478 11.601  40.279 1.00 33.03 ?  247  SER A HB3  1 
ATOM   3627  H HG   . SER A 1 281 ? -14.795 11.227  38.925 1.00 48.53 ?  247  SER A HG   1 
ATOM   3628  N N    . GLU A 1 282 ? -19.053 9.185   41.688 1.00 19.56 ?  248  GLU A N    1 
ATOM   3629  C CA   . GLU A 1 282 ? -20.496 9.038   41.773 1.00 20.06 ?  248  GLU A CA   1 
ATOM   3630  C C    . GLU A 1 282 ? -21.240 10.374  41.757 1.00 18.82 ?  248  GLU A C    1 
ATOM   3631  O O    . GLU A 1 282 ? -20.700 11.447  42.072 1.00 20.71 ?  248  GLU A O    1 
ATOM   3632  C CB   . GLU A 1 282 ? -20.892 8.198   42.999 1.00 19.51 ?  248  GLU A CB   1 
ATOM   3633  C CG   . GLU A 1 282 ? -20.718 8.890   44.374 1.00 23.18 ?  248  GLU A CG   1 
ATOM   3634  C CD   . GLU A 1 282 ? -19.302 8.819   44.945 1.00 26.88 ?  248  GLU A CD   1 
ATOM   3635  O OE1  . GLU A 1 282 ? -18.351 8.341   44.280 1.00 24.53 ?  248  GLU A OE1  1 
ATOM   3636  O OE2  . GLU A 1 282 ? -19.122 9.267   46.107 1.00 35.42 ?  248  GLU A OE2  1 
ATOM   3637  H H    . GLU A 1 282 ? -18.622 8.965   42.399 1.00 23.48 ?  248  GLU A H    1 
ATOM   3638  H HA   . GLU A 1 282 ? -20.792 8.564   40.979 1.00 24.07 ?  248  GLU A HA   1 
ATOM   3639  H HB2  . GLU A 1 282 ? -21.828 7.959   42.914 1.00 23.41 ?  248  GLU A HB2  1 
ATOM   3640  H HB3  . GLU A 1 282 ? -20.344 7.398   43.009 1.00 23.41 ?  248  GLU A HB3  1 
ATOM   3641  H HG2  . GLU A 1 282 ? -20.949 9.827   44.280 1.00 27.81 ?  248  GLU A HG2  1 
ATOM   3642  H HG3  . GLU A 1 282 ? -21.312 8.464   45.012 1.00 27.81 ?  248  GLU A HG3  1 
ATOM   3643  N N    . ALA A 1 283 ? -22.497 10.299  41.362 1.00 18.37 ?  249  ALA A N    1 
ATOM   3644  C CA   . ALA A 1 283 ? -23.395 11.438  41.307 1.00 22.19 ?  249  ALA A CA   1 
ATOM   3645  C C    . ALA A 1 283 ? -24.824 10.922  41.403 1.00 19.70 ?  249  ALA A C    1 
ATOM   3646  O O    . ALA A 1 283 ? -25.048 9.721   41.558 1.00 19.03 ?  249  ALA A O    1 
ATOM   3647  C CB   . ALA A 1 283 ? -23.177 12.243  40.020 1.00 23.11 ?  249  ALA A CB   1 
ATOM   3648  H H    . ALA A 1 283 ? -22.872 9.567   41.110 1.00 22.05 ?  249  ALA A H    1 
ATOM   3649  H HA   . ALA A 1 283 ? -23.225 12.015  42.068 1.00 26.63 ?  249  ALA A HA   1 
ATOM   3650  H HB1  . ALA A 1 283 ? -23.778 13.004  40.018 1.00 27.73 ?  249  ALA A HB1  1 
ATOM   3651  H HB2  . ALA A 1 283 ? -22.257 12.548  39.991 1.00 27.73 ?  249  ALA A HB2  1 
ATOM   3652  H HB3  . ALA A 1 283 ? -23.361 11.674  39.257 1.00 27.73 ?  249  ALA A HB3  1 
ATOM   3653  N N    . PHE A 1 284 ? -25.796 11.823  41.308 1.00 19.82 ?  250  PHE A N    1 
ATOM   3654  C CA   . PHE A 1 284 ? -27.208 11.484  41.206 1.00 20.05 ?  250  PHE A CA   1 
ATOM   3655  C C    . PHE A 1 284 ? -27.742 10.810  42.469 1.00 20.77 ?  250  PHE A C    1 
ATOM   3656  O O    . PHE A 1 284 ? -28.723 10.061  42.397 1.00 25.93 ?  250  PHE A O    1 
ATOM   3657  C CB   . PHE A 1 284 ? -27.505 10.643  39.959 1.00 20.72 ?  250  PHE A CB   1 
ATOM   3658  C CG   . PHE A 1 284 ? -26.615 10.966  38.780 1.00 18.41 ?  250  PHE A CG   1 
ATOM   3659  C CD1  . PHE A 1 284 ? -26.686 12.181  38.155 1.00 20.62 ?  250  PHE A CD1  1 
ATOM   3660  C CD2  . PHE A 1 284 ? -25.727 10.022  38.308 1.00 20.69 ?  250  PHE A CD2  1 
ATOM   3661  C CE1  . PHE A 1 284 ? -25.859 12.468  37.083 1.00 20.84 ?  250  PHE A CE1  1 
ATOM   3662  C CE2  . PHE A 1 284 ? -24.900 10.309  37.238 1.00 22.31 ?  250  PHE A CE2  1 
ATOM   3663  C CZ   . PHE A 1 284 ? -24.980 11.548  36.629 1.00 18.24 ?  250  PHE A CZ   1 
ATOM   3664  H H    . PHE A 1 284 ? -25.654 12.671  41.302 1.00 23.79 ?  250  PHE A H    1 
ATOM   3665  H HA   . PHE A 1 284 ? -27.707 12.310  41.106 1.00 24.07 ?  250  PHE A HA   1 
ATOM   3666  H HB2  . PHE A 1 284 ? -27.378 9.707   40.177 1.00 24.87 ?  250  PHE A HB2  1 
ATOM   3667  H HB3  . PHE A 1 284 ? -28.423 10.800  39.689 1.00 24.87 ?  250  PHE A HB3  1 
ATOM   3668  H HD1  . PHE A 1 284 ? -27.294 12.819  38.453 1.00 24.74 ?  250  PHE A HD1  1 
ATOM   3669  H HD2  . PHE A 1 284 ? -25.684 9.186   38.713 1.00 24.83 ?  250  PHE A HD2  1 
ATOM   3670  H HE1  . PHE A 1 284 ? -25.909 13.301  36.673 1.00 25.01 ?  250  PHE A HE1  1 
ATOM   3671  H HE2  . PHE A 1 284 ? -24.295 9.674   36.930 1.00 26.77 ?  250  PHE A HE2  1 
ATOM   3672  H HZ   . PHE A 1 284 ? -24.430 11.748  35.906 1.00 21.89 ?  250  PHE A HZ   1 
ATOM   3673  N N    . GLY A 1 285 ? -27.108 11.049  43.617 1.00 22.87 ?  251  GLY A N    1 
ATOM   3674  C CA   . GLY A 1 285 ? -27.490 10.409  44.870 1.00 23.36 ?  251  GLY A CA   1 
ATOM   3675  C C    . GLY A 1 285 ? -27.070 8.962   44.998 1.00 26.38 ?  251  GLY A C    1 
ATOM   3676  O O    . GLY A 1 285 ? -27.440 8.295   45.965 1.00 28.57 ?  251  GLY A O    1 
ATOM   3677  H H    . GLY A 1 285 ? -26.442 11.588  43.696 1.00 27.44 ?  251  GLY A H    1 
ATOM   3678  H HA2  . GLY A 1 285 ? -27.089 10.900  45.604 1.00 28.04 ?  251  GLY A HA2  1 
ATOM   3679  H HA3  . GLY A 1 285 ? -28.455 10.446  44.955 1.00 28.04 ?  251  GLY A HA3  1 
ATOM   3680  N N    . MET A 1 286 ? -26.351 8.457   43.999 1.00 23.05 ?  252  MET A N    1 
ATOM   3681  C CA   . MET A 1 286 ? -25.923 7.045   43.982 1.00 23.43 ?  252  MET A CA   1 
ATOM   3682  C C    . MET A 1 286 ? -24.713 6.900   44.884 1.00 21.18 ?  252  MET A C    1 
ATOM   3683  O O    . MET A 1 286 ? -23.911 7.819   44.958 1.00 23.80 ?  252  MET A O    1 
ATOM   3684  C CB   . MET A 1 286 ? -25.522 6.588   42.577 1.00 24.55 ?  252  MET A CB   1 
ATOM   3685  C CG   . MET A 1 286 ? -26.595 6.719   41.531 1.00 19.53 ?  252  MET A CG   1 
ATOM   3686  S SD   . MET A 1 286 ? -25.973 6.190   39.907 1.00 19.60 ?  252  MET A SD   1 
ATOM   3687  C CE   . MET A 1 286 ? -25.988 4.408   40.100 1.00 21.72 ?  252  MET A CE   1 
ATOM   3688  H H    . MET A 1 286 ? -26.068 8.943   43.282 1.00 27.67 ?  252  MET A H    1 
ATOM   3689  H HA   . MET A 1 286 ? -26.654 6.482   44.324 1.00 28.11 ?  252  MET A HA   1 
ATOM   3690  H HB2  . MET A 1 286 ? -24.744 7.109   42.294 1.00 29.45 ?  252  MET A HB2  1 
ATOM   3691  H HB3  . MET A 1 286 ? -25.244 5.651   42.626 1.00 29.45 ?  252  MET A HB3  1 
ATOM   3692  H HG2  . MET A 1 286 ? -27.364 6.164   41.779 1.00 23.44 ?  252  MET A HG2  1 
ATOM   3693  H HG3  . MET A 1 286 ? -26.890 7.654   41.477 1.00 23.44 ?  252  MET A HG3  1 
ATOM   3694  H HE1  . MET A 1 286 ? -25.624 3.995   39.306 1.00 26.06 ?  252  MET A HE1  1 
ATOM   3695  H HE2  . MET A 1 286 ? -25.451 4.163   40.865 1.00 26.06 ?  252  MET A HE2  1 
ATOM   3696  H HE3  . MET A 1 286 ? -26.895 4.106   40.234 1.00 26.06 ?  252  MET A HE3  1 
ATOM   3697  N N    . SER A 1 287 ? -24.605 5.789   45.587 1.00 20.67 ?  253  SER A N    1 
ATOM   3698  C CA   . SER A 1 287 ? -23.377 5.541   46.311 1.00 20.49 ?  253  SER A CA   1 
ATOM   3699  C C    . SER A 1 287 ? -22.231 5.251   45.339 1.00 20.85 ?  253  SER A C    1 
ATOM   3700  O O    . SER A 1 287 ? -22.454 4.883   44.186 1.00 20.17 ?  253  SER A O    1 
ATOM   3701  C CB   . SER A 1 287 ? -23.542 4.357   47.274 1.00 22.35 ?  253  SER A CB   1 
ATOM   3702  O OG   . SER A 1 287 ? -23.567 3.129   46.553 1.00 24.77 ?  253  SER A OG   1 
ATOM   3703  H H    . SER A 1 287 ? -25.211 5.184   45.659 1.00 24.80 ?  253  SER A H    1 
ATOM   3704  H HA   . SER A 1 287 ? -23.152 6.328   46.832 1.00 24.59 ?  253  SER A HA   1 
ATOM   3705  H HB2  . SER A 1 287 ? -22.797 4.346   47.894 1.00 26.82 ?  253  SER A HB2  1 
ATOM   3706  H HB3  . SER A 1 287 ? -24.376 4.457   47.759 1.00 26.82 ?  253  SER A HB3  1 
ATOM   3707  H HG   . SER A 1 287 ? -23.537 2.482   47.088 1.00 29.73 ?  253  SER A HG   1 
ATOM   3708  N N    . ASN A 1 288 ? -21.001 5.374   45.823 1.00 21.24 ?  254  ASN A N    1 
ATOM   3709  C CA   . ASN A 1 288 ? -19.845 5.018   45.003 1.00 21.50 ?  254  ASN A CA   1 
ATOM   3710  C C    . ASN A 1 288 ? -19.975 3.598   44.454 1.00 21.59 ?  254  ASN A C    1 
ATOM   3711  O O    . ASN A 1 288 ? -19.782 3.354   43.247 1.00 20.96 ?  254  ASN A O    1 
ATOM   3712  C CB   . ASN A 1 288 ? -18.550 5.186   45.800 1.00 24.24 ?  254  ASN A CB   1 
ATOM   3713  C CG   . ASN A 1 288 ? -17.325 4.838   44.992 1.00 26.70 ?  254  ASN A CG   1 
ATOM   3714  O OD1  . ASN A 1 288 ? -16.748 3.773   45.158 1.00 27.56 ?  254  ASN A OD1  1 
ATOM   3715  N ND2  . ASN A 1 288 ? -16.919 5.747   44.123 1.00 28.43 ?  254  ASN A ND2  1 
ATOM   3716  H H    . ASN A 1 288 ? -20.808 5.658   46.611 1.00 25.49 ?  254  ASN A H    1 
ATOM   3717  H HA   . ASN A 1 288 ? -19.802 5.626   44.248 1.00 25.80 ?  254  ASN A HA   1 
ATOM   3718  H HB2  . ASN A 1 288 ? -18.470 6.110   46.084 1.00 29.09 ?  254  ASN A HB2  1 
ATOM   3719  H HB3  . ASN A 1 288 ? -18.576 4.602   46.574 1.00 29.09 ?  254  ASN A HB3  1 
ATOM   3720  H HD21 . ASN A 1 288 ? -16.226 5.598   43.637 1.00 34.12 ?  254  ASN A HD21 1 
ATOM   3721  H HD22 . ASN A 1 288 ? -17.349 6.487   44.043 1.00 34.12 ?  254  ASN A HD22 1 
ATOM   3722  N N    . ALA A 1 289 ? -20.344 2.631   45.309 1.00 21.45 ?  255  ALA A N    1 
ATOM   3723  C CA   . ALA A 1 289 ? -20.459 1.252   44.850 1.00 17.90 ?  255  ALA A CA   1 
ATOM   3724  C C    . ALA A 1 289 ? -21.575 1.092   43.841 1.00 18.28 ?  255  ALA A C    1 
ATOM   3725  O O    . ALA A 1 289 ? -21.401 0.404   42.829 1.00 19.62 ?  255  ALA A O    1 
ATOM   3726  C CB   . ALA A 1 289 ? -20.674 0.281   46.022 1.00 23.34 ?  255  ALA A CB   1 
ATOM   3727  H H    . ALA A 1 289 ? -20.527 2.751   46.141 1.00 25.74 ?  255  ALA A H    1 
ATOM   3728  H HA   . ALA A 1 289 ? -19.618 1.019   44.427 1.00 21.48 ?  255  ALA A HA   1 
ATOM   3729  H HB1  . ALA A 1 289 ? -20.746 -0.622  45.675 1.00 28.01 ?  255  ALA A HB1  1 
ATOM   3730  H HB2  . ALA A 1 289 ? -19.918 0.344   46.626 1.00 28.01 ?  255  ALA A HB2  1 
ATOM   3731  H HB3  . ALA A 1 289 ? -21.490 0.523   46.487 1.00 28.01 ?  255  ALA A HB3  1 
ATOM   3732  N N    . GLU A 1 290 ? -22.744 1.684   44.088 1.00 18.87 ?  256  GLU A N    1 
ATOM   3733  C CA   . GLU A 1 290 ? -23.850 1.570   43.139 1.00 19.38 ?  256  GLU A CA   1 
ATOM   3734  C C    . GLU A 1 290 ? -23.470 2.121   41.763 1.00 19.01 ?  256  GLU A C    1 
ATOM   3735  O O    . GLU A 1 290 ? -23.814 1.544   40.718 1.00 18.37 ?  256  GLU A O    1 
ATOM   3736  C CB   . GLU A 1 290 ? -25.069 2.336   43.654 1.00 22.15 ?  256  GLU A CB   1 
ATOM   3737  C CG   . GLU A 1 290 ? -25.750 1.723   44.893 1.00 29.44 ?  256  GLU A CG   1 
ATOM   3738  C CD   . GLU A 1 290 ? -26.804 2.650   45.534 1.00 34.97 ?  256  GLU A CD   1 
ATOM   3739  O OE1  . GLU A 1 290 ? -26.690 3.902   45.467 1.00 26.32 ?  256  GLU A OE1  1 
ATOM   3740  O OE2  . GLU A 1 290 ? -27.758 2.104   46.140 1.00 39.17 ?  256  GLU A OE2  1 
ATOM   3741  H H    . GLU A 1 290 ? -22.920 2.151   44.788 1.00 22.64 ?  256  GLU A H    1 
ATOM   3742  H HA   . GLU A 1 290 ? -24.074 0.630   43.055 1.00 23.25 ?  256  GLU A HA   1 
ATOM   3743  H HB2  . GLU A 1 290 ? -24.790 3.234   43.891 1.00 26.58 ?  256  GLU A HB2  1 
ATOM   3744  H HB3  . GLU A 1 290 ? -25.731 2.371   42.946 1.00 26.58 ?  256  GLU A HB3  1 
ATOM   3745  H HG2  . GLU A 1 290 ? -26.196 0.902   44.633 1.00 35.33 ?  256  GLU A HG2  1 
ATOM   3746  H HG3  . GLU A 1 290 ? -25.074 1.536   45.563 1.00 35.33 ?  256  GLU A HG3  1 
ATOM   3747  N N    . TYR A 1 291 ? -22.804 3.269   41.752 1.00 18.34 ?  257  TYR A N    1 
ATOM   3748  C CA   . TYR A 1 291 ? -22.385 3.902   40.507 1.00 16.99 ?  257  TYR A CA   1 
ATOM   3749  C C    . TYR A 1 291 ? -21.377 3.036   39.761 1.00 16.39 ?  257  TYR A C    1 
ATOM   3750  O O    . TYR A 1 291 ? -21.490 2.876   38.537 1.00 16.89 ?  257  TYR A O    1 
ATOM   3751  C CB   . TYR A 1 291 ? -21.783 5.247   40.903 1.00 16.99 ?  257  TYR A CB   1 
ATOM   3752  C CG   . TYR A 1 291 ? -21.320 6.159   39.783 1.00 15.85 ?  257  TYR A CG   1 
ATOM   3753  C CD1  . TYR A 1 291 ? -22.175 7.082   39.214 1.00 17.03 ?  257  TYR A CD1  1 
ATOM   3754  C CD2  . TYR A 1 291 ? -20.021 6.103   39.328 1.00 17.43 ?  257  TYR A CD2  1 
ATOM   3755  C CE1  . TYR A 1 291 ? -21.739 7.943   38.226 1.00 16.85 ?  257  TYR A CE1  1 
ATOM   3756  C CE2  . TYR A 1 291 ? -19.581 6.950   38.332 1.00 17.23 ?  257  TYR A CE2  1 
ATOM   3757  C CZ   . TYR A 1 291 ? -20.445 7.848   37.797 1.00 18.39 ?  257  TYR A CZ   1 
ATOM   3758  O OH   . TYR A 1 291 ? -20.047 8.741   36.810 1.00 18.88 ?  257  TYR A OH   1 
ATOM   3759  H H    . TYR A 1 291 ? -22.580 3.708   42.457 1.00 22.00 ?  257  TYR A H    1 
ATOM   3760  H HA   . TYR A 1 291 ? -23.129 4.033   39.898 1.00 20.39 ?  257  TYR A HA   1 
ATOM   3761  H HB2  . TYR A 1 291 ? -22.453 5.736   41.406 1.00 20.38 ?  257  TYR A HB2  1 
ATOM   3762  H HB3  . TYR A 1 291 ? -21.010 5.074   41.462 1.00 20.38 ?  257  TYR A HB3  1 
ATOM   3763  H HD1  . TYR A 1 291 ? -23.058 7.125   39.501 1.00 20.44 ?  257  TYR A HD1  1 
ATOM   3764  H HD2  . TYR A 1 291 ? -19.433 5.485   39.698 1.00 20.91 ?  257  TYR A HD2  1 
ATOM   3765  H HE1  . TYR A 1 291 ? -22.315 8.575   37.860 1.00 20.22 ?  257  TYR A HE1  1 
ATOM   3766  H HE2  . TYR A 1 291 ? -18.702 6.905   38.031 1.00 20.68 ?  257  TYR A HE2  1 
ATOM   3767  H HH   . TYR A 1 291 ? -19.209 8.799   36.796 1.00 22.66 ?  257  TYR A HH   1 
ATOM   3768  N N    . LEU A 1 292 ? -20.394 2.479   40.468 1.00 15.61 ?  258  LEU A N    1 
ATOM   3769  C CA   . LEU A 1 292 ? -19.439 1.597   39.804 1.00 17.20 ?  258  LEU A CA   1 
ATOM   3770  C C    . LEU A 1 292 ? -20.103 0.320   39.289 1.00 18.32 ?  258  LEU A C    1 
ATOM   3771  O O    . LEU A 1 292 ? -19.729 -0.180  38.225 1.00 17.77 ?  258  LEU A O    1 
ATOM   3772  C CB   . LEU A 1 292 ? -18.240 1.318   40.691 1.00 16.27 ?  258  LEU A CB   1 
ATOM   3773  C CG   . LEU A 1 292 ? -17.112 2.356   40.582 1.00 19.54 ?  258  LEU A CG   1 
ATOM   3774  C CD1  . LEU A 1 292 ? -16.257 2.335   41.816 1.00 20.06 ?  258  LEU A CD1  1 
ATOM   3775  C CD2  . LEU A 1 292 ? -16.265 2.046   39.366 1.00 19.24 ?  258  LEU A CD2  1 
ATOM   3776  H H    . LEU A 1 292 ? -20.263 2.592   41.310 1.00 18.74 ?  258  LEU A H    1 
ATOM   3777  H HA   . LEU A 1 292 ? -19.090 2.058   39.025 1.00 20.64 ?  258  LEU A HA   1 
ATOM   3778  H HB2  . LEU A 1 292 ? -18.537 1.302   41.614 1.00 19.52 ?  258  LEU A HB2  1 
ATOM   3779  H HB3  . LEU A 1 292 ? -17.870 0.455   40.446 1.00 19.52 ?  258  LEU A HB3  1 
ATOM   3780  H HG   . LEU A 1 292 ? -17.494 3.243   40.494 1.00 23.45 ?  258  LEU A HG   1 
ATOM   3781  H HD11 . LEU A 1 292 ? -15.526 2.962   41.703 1.00 24.07 ?  258  LEU A HD11 1 
ATOM   3782  H HD12 . LEU A 1 292 ? -16.798 2.592   42.579 1.00 24.07 ?  258  LEU A HD12 1 
ATOM   3783  H HD13 . LEU A 1 292 ? -15.909 1.439   41.944 1.00 24.07 ?  258  LEU A HD13 1 
ATOM   3784  H HD21 . LEU A 1 292 ? -15.517 2.663   39.338 1.00 23.08 ?  258  LEU A HD21 1 
ATOM   3785  H HD22 . LEU A 1 292 ? -15.941 1.135   39.431 1.00 23.08 ?  258  LEU A HD22 1 
ATOM   3786  H HD23 . LEU A 1 292 ? -16.809 2.148   38.569 1.00 23.08 ?  258  LEU A HD23 1 
ATOM   3787  N N    . VAL A 1 293 ? -21.089 -0.236  40.014 1.00 16.80 ?  259  VAL A N    1 
ATOM   3788  C CA   . VAL A 1 293 ? -21.775 -1.429  39.509 1.00 18.06 ?  259  VAL A CA   1 
ATOM   3789  C C    . VAL A 1 293 ? -22.365 -1.157  38.132 1.00 16.27 ?  259  VAL A C    1 
ATOM   3790  O O    . VAL A 1 293 ? -22.222 -1.957  37.204 1.00 17.21 ?  259  VAL A O    1 
ATOM   3791  C CB   . VAL A 1 293 ? -22.851 -1.899  40.509 1.00 19.92 ?  259  VAL A CB   1 
ATOM   3792  C CG1  . VAL A 1 293 ? -23.846 -2.844  39.829 1.00 18.05 ?  259  VAL A CG1  1 
ATOM   3793  C CG2  . VAL A 1 293 ? -22.194 -2.556  41.706 1.00 21.77 ?  259  VAL A CG2  1 
ATOM   3794  H H    . VAL A 1 293 ? -21.367 0.052   40.775 1.00 20.16 ?  259  VAL A H    1 
ATOM   3795  H HA   . VAL A 1 293 ? -21.125 -2.143  39.418 1.00 21.67 ?  259  VAL A HA   1 
ATOM   3796  H HB   . VAL A 1 293 ? -23.353 -1.132  40.826 1.00 23.91 ?  259  VAL A HB   1 
ATOM   3797  H HG11 . VAL A 1 293 ? -24.374 -3.290  40.510 1.00 21.66 ?  259  VAL A HG11 1 
ATOM   3798  H HG12 . VAL A 1 293 ? -24.425 -2.327  39.247 1.00 21.66 ?  259  VAL A HG12 1 
ATOM   3799  H HG13 . VAL A 1 293 ? -23.355 -3.499  39.309 1.00 21.66 ?  259  VAL A HG13 1 
ATOM   3800  H HG21 . VAL A 1 293 ? -22.871 -2.743  42.375 1.00 26.12 ?  259  VAL A HG21 1 
ATOM   3801  H HG22 . VAL A 1 293 ? -21.773 -3.382  41.422 1.00 26.12 ?  259  VAL A HG22 1 
ATOM   3802  H HG23 . VAL A 1 293 ? -21.527 -1.953  42.070 1.00 26.12 ?  259  VAL A HG23 1 
ATOM   3803  N N    . GLU A 1 294 ? -23.030 -0.015  37.966 1.00 16.29 ?  260  GLU A N    1 
ATOM   3804  C CA   . GLU A 1 294 ? -23.625 0.307   36.673 1.00 16.73 ?  260  GLU A CA   1 
ATOM   3805  C C    . GLU A 1 294 ? -22.542 0.529   35.617 1.00 17.66 ?  260  GLU A C    1 
ATOM   3806  O O    . GLU A 1 294 ? -22.688 0.087   34.459 1.00 16.30 ?  260  GLU A O    1 
ATOM   3807  C CB   . GLU A 1 294 ? -24.520 1.523   36.785 1.00 17.45 ?  260  GLU A CB   1 
ATOM   3808  C CG   . GLU A 1 294 ? -25.888 1.190   37.435 1.00 18.60 ?  260  GLU A CG   1 
ATOM   3809  C CD   . GLU A 1 294 ? -26.942 2.215   37.215 1.00 22.01 ?  260  GLU A CD   1 
ATOM   3810  O OE1  . GLU A 1 294 ? -26.808 3.044   36.299 1.00 18.81 ?  260  GLU A OE1  1 
ATOM   3811  O OE2  . GLU A 1 294 ? -27.983 2.167   37.919 1.00 25.11 ?  260  GLU A OE2  1 
ATOM   3812  H H    . GLU A 1 294 ? -23.150 0.580   38.575 1.00 19.55 ?  260  GLU A H    1 
ATOM   3813  H HA   . GLU A 1 294 ? -24.181 -0.437  36.392 1.00 20.08 ?  260  GLU A HA   1 
ATOM   3814  H HB2  . GLU A 1 294 ? -24.079 2.191   37.334 1.00 20.94 ?  260  GLU A HB2  1 
ATOM   3815  H HB3  . GLU A 1 294 ? -24.685 1.878   35.898 1.00 20.94 ?  260  GLU A HB3  1 
ATOM   3816  H HG2  . GLU A 1 294 ? -26.211 0.354   37.064 1.00 22.33 ?  260  GLU A HG2  1 
ATOM   3817  H HG3  . GLU A 1 294 ? -25.762 1.101   38.393 1.00 22.33 ?  260  GLU A HG3  1 
ATOM   3818  N N    . GLY A 1 295 ? -21.455 1.208   35.984 1.00 15.44 ?  261  GLY A N    1 
ATOM   3819  C CA   . GLY A 1 295 ? -20.408 1.449   34.998 1.00 15.73 ?  261  GLY A CA   1 
ATOM   3820  C C    . GLY A 1 295 ? -19.734 0.158   34.557 1.00 15.20 ?  261  GLY A C    1 
ATOM   3821  O O    . GLY A 1 295 ? -19.409 -0.035  33.371 1.00 15.47 ?  261  GLY A O    1 
ATOM   3822  H H    . GLY A 1 295 ? -21.306 1.528   36.769 1.00 18.53 ?  261  GLY A H    1 
ATOM   3823  H HA2  . GLY A 1 295 ? -20.792 1.878   34.217 1.00 18.88 ?  261  GLY A HA2  1 
ATOM   3824  H HA3  . GLY A 1 295 ? -19.734 2.034   35.379 1.00 18.88 ?  261  GLY A HA3  1 
ATOM   3825  N N    . ILE A 1 296 ? -19.508 -0.740  35.511 1.00 15.54 ?  262  ILE A N    1 
ATOM   3826  C CA   . ILE A 1 296 ? -18.895 -2.032  35.208 1.00 15.30 ?  262  ILE A CA   1 
ATOM   3827  C C    . ILE A 1 296 ? -19.781 -2.840  34.262 1.00 14.37 ?  262  ILE A C    1 
ATOM   3828  O O    . ILE A 1 296 ? -19.306 -3.436  33.282 1.00 14.95 ?  262  ILE A O    1 
ATOM   3829  C CB   . ILE A 1 296 ? -18.600 -2.784  36.529 1.00 16.60 ?  262  ILE A CB   1 
ATOM   3830  C CG1  . ILE A 1 296 ? -17.417 -2.137  37.265 1.00 15.90 ?  262  ILE A CG1  1 
ATOM   3831  C CG2  . ILE A 1 296 ? -18.408 -4.285  36.254 1.00 15.37 ?  262  ILE A CG2  1 
ATOM   3832  C CD1  . ILE A 1 296 ? -17.248 -2.601  38.721 1.00 17.96 ?  262  ILE A CD1  1 
ATOM   3833  H H    . ILE A 1 296 ? -19.698 -0.628  36.342 1.00 18.64 ?  262  ILE A H    1 
ATOM   3834  H HA   . ILE A 1 296 ? -18.052 -1.888  34.751 1.00 18.36 ?  262  ILE A HA   1 
ATOM   3835  H HB   . ILE A 1 296 ? -19.362 -2.707  37.125 1.00 19.92 ?  262  ILE A HB   1 
ATOM   3836  H HG12 . ILE A 1 296 ? -16.600 -2.355  36.790 1.00 19.08 ?  262  ILE A HG12 1 
ATOM   3837  H HG13 . ILE A 1 296 ? -17.548 -1.176  37.276 1.00 19.08 ?  262  ILE A HG13 1 
ATOM   3838  H HG21 . ILE A 1 296 ? -18.079 -4.714  37.059 1.00 18.45 ?  262  ILE A HG21 1 
ATOM   3839  H HG22 . ILE A 1 296 ? -19.261 -4.671  35.998 1.00 18.45 ?  262  ILE A HG22 1 
ATOM   3840  H HG23 . ILE A 1 296 ? -17.767 -4.395  35.534 1.00 18.45 ?  262  ILE A HG23 1 
ATOM   3841  H HD11 . ILE A 1 296 ? -16.419 -2.240  39.073 1.00 21.55 ?  262  ILE A HD11 1 
ATOM   3842  H HD12 . ILE A 1 296 ? -17.998 -2.278  39.245 1.00 21.55 ?  262  ILE A HD12 1 
ATOM   3843  H HD13 . ILE A 1 296 ? -17.222 -3.570  38.743 1.00 21.55 ?  262  ILE A HD13 1 
ATOM   3844  N N    . GLU A 1 297 ? -21.073 -2.874  34.532 1.00 15.30 ?  263  GLU A N    1 
ATOM   3845  C CA   . GLU A 1 297 ? -22.005 -3.575  33.658 1.00 16.97 ?  263  GLU A CA   1 
ATOM   3846  C C    . GLU A 1 297 ? -21.953 -3.034  32.234 1.00 16.66 ?  263  GLU A C    1 
ATOM   3847  O O    . GLU A 1 297 ? -21.888 -3.809  31.274 1.00 16.23 ?  263  GLU A O    1 
ATOM   3848  C CB   . GLU A 1 297 ? -23.435 -3.483  34.220 1.00 18.69 ?  263  GLU A CB   1 
ATOM   3849  C CG   . GLU A 1 297 ? -24.539 -3.842  33.200 1.00 25.58 ?  263  GLU A CG   1 
ATOM   3850  C CD   . GLU A 1 297 ? -24.549 -5.312  32.879 1.00 34.49 ?  263  GLU A CD   1 
ATOM   3851  O OE1  . GLU A 1 297 ? -23.937 -6.069  33.650 1.00 35.49 ?  263  GLU A OE1  1 
ATOM   3852  O OE2  . GLU A 1 297 ? -25.179 -5.711  31.865 1.00 43.64 ?  263  GLU A OE2  1 
ATOM   3853  H H    . GLU A 1 297 ? -21.441 -2.501  35.214 1.00 18.36 ?  263  GLU A H    1 
ATOM   3854  H HA   . GLU A 1 297 ? -21.751 -4.510  33.631 1.00 20.37 ?  263  GLU A HA   1 
ATOM   3855  H HB2  . GLU A 1 297 ? -23.514 -4.096  34.967 1.00 22.43 ?  263  GLU A HB2  1 
ATOM   3856  H HB3  . GLU A 1 297 ? -23.593 -2.574  34.518 1.00 22.43 ?  263  GLU A HB3  1 
ATOM   3857  H HG2  . GLU A 1 297 ? -25.404 -3.605  33.570 1.00 30.69 ?  263  GLU A HG2  1 
ATOM   3858  H HG3  . GLU A 1 297 ? -24.385 -3.352  32.377 1.00 30.69 ?  263  GLU A HG3  1 
ATOM   3859  N N    . ALA A 1 298 ? -22.005 -1.704  32.067 1.00 14.70 ?  264  ALA A N    1 
ATOM   3860  C CA   . ALA A 1 298 ? -21.965 -1.131  30.730 1.00 13.02 ?  264  ALA A CA   1 
ATOM   3861  C C    . ALA A 1 298 ? -20.654 -1.461  30.025 1.00 15.21 ?  264  ALA A C    1 
ATOM   3862  O O    . ALA A 1 298 ? -20.631 -1.774  28.827 1.00 15.28 ?  264  ALA A O    1 
ATOM   3863  C CB   . ALA A 1 298 ? -22.090 0.387   30.841 1.00 17.27 ?  264  ALA A CB   1 
ATOM   3864  H H    . ALA A 1 298 ? -22.063 -1.128  32.703 1.00 17.65 ?  264  ALA A H    1 
ATOM   3865  H HA   . ALA A 1 298 ? -22.700 -1.492  30.210 1.00 15.62 ?  264  ALA A HA   1 
ATOM   3866  H HB1  . ALA A 1 298 ? -22.129 0.766   29.949 1.00 20.72 ?  264  ALA A HB1  1 
ATOM   3867  H HB2  . ALA A 1 298 ? -22.901 0.602   31.328 1.00 20.72 ?  264  ALA A HB2  1 
ATOM   3868  H HB3  . ALA A 1 298 ? -21.318 0.734   31.314 1.00 20.72 ?  264  ALA A HB3  1 
ATOM   3869  N N    . THR A 1 299 ? -19.553 -1.374  30.746 1.00 14.31 ?  265  THR A N    1 
ATOM   3870  C CA   . THR A 1 299 ? -18.244 -1.598  30.141 1.00 13.83 ?  265  THR A CA   1 
ATOM   3871  C C    . THR A 1 299 ? -18.081 -3.066  29.745 1.00 14.57 ?  265  THR A C    1 
ATOM   3872  O O    . THR A 1 299 ? -17.559 -3.359  28.673 1.00 13.45 ?  265  THR A O    1 
ATOM   3873  C CB   . THR A 1 299 ? -17.121 -1.165  31.100 1.00 12.93 ?  265  THR A CB   1 
ATOM   3874  O OG1  . THR A 1 299 ? -17.306 0.234   31.453 1.00 14.87 ?  265  THR A OG1  1 
ATOM   3875  C CG2  . THR A 1 299 ? -15.772 -1.279  30.435 1.00 14.08 ?  265  THR A CG2  1 
ATOM   3876  H H    . THR A 1 299 ? -19.529 -1.188  31.585 1.00 17.17 ?  265  THR A H    1 
ATOM   3877  H HA   . THR A 1 299 ? -18.170 -1.050  29.344 1.00 16.60 ?  265  THR A HA   1 
ATOM   3878  H HB   . THR A 1 299 ? -17.145 -1.734  31.886 1.00 15.52 ?  265  THR A HB   1 
ATOM   3879  H HG1  . THR A 1 299 ? -18.121 0.392   31.584 1.00 17.85 ?  265  THR A HG1  1 
ATOM   3880  H HG21 . THR A 1 299 ? -15.070 -1.075  31.072 1.00 16.90 ?  265  THR A HG21 1 
ATOM   3881  H HG22 . THR A 1 299 ? -15.642 -2.181  30.101 1.00 16.90 ?  265  THR A HG22 1 
ATOM   3882  H HG23 . THR A 1 299 ? -15.715 -0.657  29.692 1.00 16.90 ?  265  THR A HG23 1 
ATOM   3883  N N    . GLN A 1 300 ? -18.460 -3.995  30.634 1.00 15.57 ?  266  GLN A N    1 
ATOM   3884  C CA   . GLN A 1 300 ? -18.448 -5.419  30.298 1.00 13.69 ?  266  GLN A CA   1 
ATOM   3885  C C    . GLN A 1 300 ? -19.229 -5.689  29.029 1.00 14.51 ?  266  GLN A C    1 
ATOM   3886  O O    . GLN A 1 300 ? -18.737 -6.381  28.125 1.00 14.58 ?  266  GLN A O    1 
ATOM   3887  C CB   . GLN A 1 300 ? -19.031 -6.231  31.457 1.00 15.73 ?  266  GLN A CB   1 
ATOM   3888  C CG   . GLN A 1 300 ? -18.094 -6.347  32.633 1.00 14.98 ?  266  GLN A CG   1 
ATOM   3889  C CD   . GLN A 1 300 ? -18.758 -6.944  33.871 1.00 15.70 ?  266  GLN A CD   1 
ATOM   3890  O OE1  . GLN A 1 300 ? -19.988 -6.950  34.004 1.00 17.97 ?  266  GLN A OE1  1 
ATOM   3891  N NE2  . GLN A 1 300 ? -17.934 -7.465  34.766 1.00 16.72 ?  266  GLN A NE2  1 
ATOM   3892  H H    . GLN A 1 300 ? -18.725 -3.825  31.434 1.00 18.69 ?  266  GLN A H    1 
ATOM   3893  H HA   . GLN A 1 300 ? -17.530 -5.697  30.156 1.00 16.43 ?  266  GLN A HA   1 
ATOM   3894  H HB2  . GLN A 1 300 ? -19.844 -5.801  31.764 1.00 18.88 ?  266  GLN A HB2  1 
ATOM   3895  H HB3  . GLN A 1 300 ? -19.228 -7.128  31.143 1.00 18.88 ?  266  GLN A HB3  1 
ATOM   3896  H HG2  . GLN A 1 300 ? -17.350 -6.919  32.388 1.00 17.98 ?  266  GLN A HG2  1 
ATOM   3897  H HG3  . GLN A 1 300 ? -17.770 -5.462  32.866 1.00 17.98 ?  266  GLN A HG3  1 
ATOM   3898  H HE21 . GLN A 1 300 ? -17.085 -7.451  34.628 1.00 20.06 ?  266  GLN A HE21 1 
ATOM   3899  H HE22 . GLN A 1 300 ? -18.247 -7.818  35.486 1.00 20.06 ?  266  GLN A HE22 1 
ATOM   3900  N N    . LYS A 1 301 ? -20.440 -5.144  28.937 1.00 15.10 ?  267  LYS A N    1 
ATOM   3901  C CA   . LYS A 1 301 ? -21.261 -5.378  27.752 1.00 14.52 ?  267  LYS A CA   1 
ATOM   3902  C C    . LYS A 1 301 ? -20.593 -4.823  26.498 1.00 16.55 ?  267  LYS A C    1 
ATOM   3903  O O    . LYS A 1 301 ? -20.509 -5.489  25.465 1.00 15.76 ?  267  LYS A O    1 
ATOM   3904  C CB   . LYS A 1 301 ? -22.649 -4.795  27.937 1.00 17.37 ?  267  LYS A CB   1 
ATOM   3905  C CG   . LYS A 1 301 ? -23.488 -5.528  28.919 1.00 21.30 ?  267  LYS A CG   1 
ATOM   3906  H H    . LYS A 1 301 ? -20.804 -4.645  29.535 1.00 18.12 ?  267  LYS A H    1 
ATOM   3907  H HA   . LYS A 1 301 ? -21.364 -6.335  27.635 1.00 17.43 ?  267  LYS A HA   1 
ATOM   3908  H HB2  . LYS A 1 301 ? -22.563 -3.880  28.247 1.00 20.84 ?  267  LYS A HB2  1 
ATOM   3909  H HB3  . LYS A 1 301 ? -23.110 -4.813  27.084 1.00 20.84 ?  267  LYS A HB3  1 
ATOM   3910  H HG2  . LYS A 1 301 ? -23.038 -5.528  29.780 1.00 25.56 ?  267  LYS A HG2  1 
ATOM   3911  H HG3  . LYS A 1 301 ? -24.347 -5.079  28.996 1.00 25.56 ?  267  LYS A HG3  1 
ATOM   3912  N N    . ALA A 1 302 ? -20.068 -3.600  26.569 1.00 14.12 ?  268  ALA A N    1 
ATOM   3913  C CA   . ALA A 1 302 ? -19.426 -3.009  25.405 1.00 13.85 ?  268  ALA A CA   1 
ATOM   3914  C C    . ALA A 1 302 ? -18.189 -3.797  24.992 1.00 14.31 ?  268  ALA A C    1 
ATOM   3915  O O    . ALA A 1 302 ? -17.988 -4.091  23.797 1.00 14.37 ?  268  ALA A O    1 
ATOM   3916  C CB   . ALA A 1 302 ? -19.035 -1.552  25.710 1.00 15.68 ?  268  ALA A CB   1 
ATOM   3917  H H    . ALA A 1 302 ? -20.072 -3.101  27.270 1.00 16.95 ?  268  ALA A H    1 
ATOM   3918  H HA   . ALA A 1 302 ? -20.057 -3.021  24.668 1.00 16.62 ?  268  ALA A HA   1 
ATOM   3919  H HB1  . ALA A 1 302 ? -18.645 -1.157  24.915 1.00 18.82 ?  268  ALA A HB1  1 
ATOM   3920  H HB2  . ALA A 1 302 ? -19.829 -1.060  25.970 1.00 18.82 ?  268  ALA A HB2  1 
ATOM   3921  H HB3  . ALA A 1 302 ? -18.389 -1.544  26.434 1.00 18.82 ?  268  ALA A HB3  1 
ATOM   3922  N N    . ALA A 1 303 ? -17.328 -4.128  25.959 1.00 13.93 ?  269  ALA A N    1 
ATOM   3923  C CA   . ALA A 1 303 ? -16.114 -4.874  25.654 1.00 14.15 ?  269  ALA A CA   1 
ATOM   3924  C C    . ALA A 1 303 ? -16.439 -6.248  25.070 1.00 15.10 ?  269  ALA A C    1 
ATOM   3925  O O    . ALA A 1 303 ? -15.794 -6.675  24.100 1.00 14.47 ?  269  ALA A O    1 
ATOM   3926  C CB   . ALA A 1 303 ? -15.240 -5.017  26.901 1.00 14.07 ?  269  ALA A CB   1 
ATOM   3927  H H    . ALA A 1 303 ? -17.426 -3.934  26.791 1.00 16.71 ?  269  ALA A H    1 
ATOM   3928  H HA   . ALA A 1 303 ? -15.608 -4.374  24.994 1.00 16.98 ?  269  ALA A HA   1 
ATOM   3929  H HB1  . ALA A 1 303 ? -14.419 -5.474  26.660 1.00 16.89 ?  269  ALA A HB1  1 
ATOM   3930  H HB2  . ALA A 1 303 ? -15.038 -4.134  27.248 1.00 16.89 ?  269  ALA A HB2  1 
ATOM   3931  H HB3  . ALA A 1 303 ? -15.722 -5.532  27.567 1.00 16.89 ?  269  ALA A HB3  1 
ATOM   3932  N N    . GLN A 1 304 ? -17.447 -6.916  25.618 1.00 14.52 ?  270  GLN A N    1 
ATOM   3933  C CA   . GLN A 1 304 ? -17.799 -8.247  25.116 1.00 14.08 ?  270  GLN A CA   1 
ATOM   3934  C C    . GLN A 1 304 ? -18.416 -8.171  23.733 1.00 19.53 ?  270  GLN A C    1 
ATOM   3935  O O    . GLN A 1 304 ? -18.404 -9.177  23.006 1.00 17.15 ?  270  GLN A O    1 
ATOM   3936  C CB   . GLN A 1 304 ? -18.734 -8.931  26.119 1.00 16.23 ?  270  GLN A CB   1 
ATOM   3937  C CG   . GLN A 1 304 ? -18.054 -9.352  27.399 1.00 16.28 ?  270  GLN A CG   1 
ATOM   3938  C CD   . GLN A 1 304 ? -19.002 -9.706  28.538 1.00 18.50 ?  270  GLN A CD   1 
ATOM   3939  O OE1  . GLN A 1 304 ? -20.138 -10.122 28.300 1.00 24.26 ?  270  GLN A OE1  1 
ATOM   3940  N NE2  . GLN A 1 304 ? -18.544 -9.544  29.768 1.00 17.38 ?  270  GLN A NE2  1 
ATOM   3941  H H    . GLN A 1 304 ? -17.935 -6.632  26.267 1.00 17.42 ?  270  GLN A H    1 
ATOM   3942  H HA   . GLN A 1 304 ? -17.008 -8.804  25.042 1.00 16.90 ?  270  GLN A HA   1 
ATOM   3943  H HB2  . GLN A 1 304 ? -19.446 -8.314  26.352 1.00 19.47 ?  270  GLN A HB2  1 
ATOM   3944  H HB3  . GLN A 1 304 ? -19.106 -9.726  25.706 1.00 19.47 ?  270  GLN A HB3  1 
ATOM   3945  H HG2  . GLN A 1 304 ? -17.512 -10.136 27.217 1.00 19.53 ?  270  GLN A HG2  1 
ATOM   3946  H HG3  . GLN A 1 304 ? -17.491 -8.624  27.704 1.00 19.53 ?  270  GLN A HG3  1 
ATOM   3947  H HE21 . GLN A 1 304 ? -17.745 -9.252  29.894 1.00 20.86 ?  270  GLN A HE21 1 
ATOM   3948  H HE22 . GLN A 1 304 ? -19.045 -9.731  30.441 1.00 20.86 ?  270  GLN A HE22 1 
ATOM   3949  N N    . SER A 1 305 ? -18.934 -7.009  23.334 1.00 15.96 ?  271  SER A N    1 
ATOM   3950  C CA   . SER A 1 305 ? -19.421 -6.796  21.971 1.00 16.37 ?  271  SER A CA   1 
ATOM   3951  C C    . SER A 1 305 ? -18.306 -6.520  20.976 1.00 15.84 ?  271  SER A C    1 
ATOM   3952  O O    . SER A 1 305 ? -18.576 -6.362  19.780 1.00 17.07 ?  271  SER A O    1 
ATOM   3953  C CB   . SER A 1 305 ? -20.506 -5.702  21.928 1.00 17.52 ?  271  SER A CB   1 
ATOM   3954  O OG   . SER A 1 305 ? -19.977 -4.370  21.962 1.00 18.50 ?  271  SER A OG   1 
ATOM   3955  H H    . SER A 1 305 ? -19.016 -6.318  23.840 1.00 19.16 ?  271  SER A H    1 
ATOM   3956  H HA   . SER A 1 305 ? -19.861 -7.609  21.677 1.00 19.65 ?  271  SER A HA   1 
ATOM   3957  H HB2  . SER A 1 305 ? -21.013 -5.808  21.107 1.00 21.02 ?  271  SER A HB2  1 
ATOM   3958  H HB3  . SER A 1 305 ? -21.088 -5.819  22.695 1.00 21.02 ?  271  SER A HB3  1 
ATOM   3959  H HG   . SER A 1 305 ? -19.434 -4.292  22.599 1.00 22.20 ?  271  SER A HG   1 
ATOM   3960  N N    . GLY A 1 306 ? -17.055 -6.423  21.403 1.00 13.71 ?  272  GLY A N    1 
ATOM   3961  C CA   . GLY A 1 306 ? -15.972 -6.207  20.487 1.00 14.77 ?  272  GLY A CA   1 
ATOM   3962  C C    . GLY A 1 306 ? -15.580 -4.755  20.327 1.00 12.56 ?  272  GLY A C    1 
ATOM   3963  O O    . GLY A 1 306 ? -14.734 -4.465  19.486 1.00 14.62 ?  272  GLY A O    1 
ATOM   3964  H H    . GLY A 1 306 ? -16.817 -6.481  22.228 1.00 16.45 ?  272  GLY A H    1 
ATOM   3965  H HA2  . GLY A 1 306 ? -15.194 -6.694  20.801 1.00 17.72 ?  272  GLY A HA2  1 
ATOM   3966  H HA3  . GLY A 1 306 ? -16.227 -6.546  19.615 1.00 17.72 ?  272  GLY A HA3  1 
ATOM   3967  N N    . LYS A 1 307 ? -16.112 -3.865  21.154 1.00 13.96 ?  273  LYS A N    1 
ATOM   3968  C CA   . LYS A 1 307 ? -15.766 -2.438  21.096 1.00 12.53 ?  273  LYS A CA   1 
ATOM   3969  C C    . LYS A 1 307 ? -14.461 -2.220  21.863 1.00 11.84 ?  273  LYS A C    1 
ATOM   3970  O O    . LYS A 1 307 ? -14.203 -2.832  22.898 1.00 12.95 ?  273  LYS A O    1 
ATOM   3971  C CB   . LYS A 1 307 ? -16.861 -1.611  21.750 1.00 13.98 ?  273  LYS A CB   1 
ATOM   3972  C CG   . LYS A 1 307 ? -18.201 -1.677  21.057 1.00 15.78 ?  273  LYS A CG   1 
ATOM   3973  C CD   . LYS A 1 307 ? -18.267 -0.845  19.803 1.00 16.24 ?  273  LYS A CD   1 
ATOM   3974  C CE   . LYS A 1 307 ? -19.632 -0.990  19.141 1.00 19.55 ?  273  LYS A CE   1 
ATOM   3975  N NZ   . LYS A 1 307 ? -19.814 -0.125  17.955 1.00 19.61 ?  273  LYS A NZ   1 
ATOM   3976  H H    . LYS A 1 307 ? -16.684 -4.057  21.767 1.00 16.75 ?  273  LYS A H    1 
ATOM   3977  H HA   . LYS A 1 307 ? -15.665 -2.151  20.175 1.00 15.03 ?  273  LYS A HA   1 
ATOM   3978  H HB2  . LYS A 1 307 ? -16.986 -1.929  22.658 1.00 16.77 ?  273  LYS A HB2  1 
ATOM   3979  H HB3  . LYS A 1 307 ? -16.582 -0.682  21.759 1.00 16.77 ?  273  LYS A HB3  1 
ATOM   3980  H HG2  . LYS A 1 307 ? -18.383 -2.598  20.812 1.00 18.94 ?  273  LYS A HG2  1 
ATOM   3981  H HG3  . LYS A 1 307 ? -18.885 -1.355  21.664 1.00 18.94 ?  273  LYS A HG3  1 
ATOM   3982  H HD2  . LYS A 1 307 ? -18.128 0.089   20.025 1.00 19.48 ?  273  LYS A HD2  1 
ATOM   3983  H HD3  . LYS A 1 307 ? -17.587 -1.142  19.179 1.00 19.48 ?  273  LYS A HD3  1 
ATOM   3984  H HE2  . LYS A 1 307 ? -19.745 -1.911  18.856 1.00 23.45 ?  273  LYS A HE2  1 
ATOM   3985  H HE3  . LYS A 1 307 ? -20.319 -0.756  19.786 1.00 23.45 ?  273  LYS A HE3  1 
ATOM   3986  H HZ1  . LYS A 1 307 ? -19.694 0.728   18.179 1.00 23.53 ?  273  LYS A HZ1  1 
ATOM   3987  H HZ2  . LYS A 1 307 ? -19.224 -0.344  17.326 1.00 23.53 ?  273  LYS A HZ2  1 
ATOM   3988  H HZ3  . LYS A 1 307 ? -20.636 -0.225  17.628 1.00 23.53 ?  273  LYS A HZ3  1 
ATOM   3989  N N    . ILE A 1 308 ? -13.639 -1.303  21.347 1.00 11.22 ?  274  ILE A N    1 
ATOM   3990  C CA   . ILE A 1 308 ? -12.475 -0.827  22.086 1.00 11.57 ?  274  ILE A CA   1 
ATOM   3991  C C    . ILE A 1 308 ? -12.933 -0.076  23.335 1.00 10.75 ?  274  ILE A C    1 
ATOM   3992  O O    . ILE A 1 308 ? -13.926 0.667   23.304 1.00 12.33 ?  274  ILE A O    1 
ATOM   3993  C CB   . ILE A 1 308 ? -11.646 0.124   21.206 1.00 12.52 ?  274  ILE A CB   1 
ATOM   3994  C CG1  . ILE A 1 308 ? -11.101 -0.604  19.984 1.00 14.31 ?  274  ILE A CG1  1 
ATOM   3995  C CG2  . ILE A 1 308 ? -10.504 0.744   21.987 1.00 12.00 ?  274  ILE A CG2  1 
ATOM   3996  C CD1  . ILE A 1 308 ? -10.507 0.326   18.943 1.00 14.14 ?  274  ILE A CD1  1 
ATOM   3997  H H    . ILE A 1 308 ? -13.736 -0.942  20.573 1.00 13.46 ?  274  ILE A H    1 
ATOM   3998  H HA   . ILE A 1 308 ? -11.937 -1.593  22.342 1.00 13.89 ?  274  ILE A HA   1 
ATOM   3999  H HB   . ILE A 1 308 ? -12.241 0.832   20.913 1.00 15.02 ?  274  ILE A HB   1 
ATOM   4000  H HG12 . ILE A 1 308 ? -10.403 -1.215  20.269 1.00 17.17 ?  274  ILE A HG12 1 
ATOM   4001  H HG13 . ILE A 1 308 ? -11.823 -1.097  19.565 1.00 17.17 ?  274  ILE A HG13 1 
ATOM   4002  H HG21 . ILE A 1 308 ? -9.995  1.321   21.397 1.00 14.40 ?  274  ILE A HG21 1 
ATOM   4003  H HG22 . ILE A 1 308 ? -10.868 1.261   22.723 1.00 14.40 ?  274  ILE A HG22 1 
ATOM   4004  H HG23 . ILE A 1 308 ? -9.935  0.037   22.330 1.00 14.40 ?  274  ILE A HG23 1 
ATOM   4005  H HD11 . ILE A 1 308 ? -10.444 -0.145  18.098 1.00 16.97 ?  274  ILE A HD11 1 
ATOM   4006  H HD12 . ILE A 1 308 ? -11.083 1.101   18.847 1.00 16.97 ?  274  ILE A HD12 1 
ATOM   4007  H HD13 . ILE A 1 308 ? -9.624  0.604   19.234 1.00 16.97 ?  274  ILE A HD13 1 
ATOM   4008  N N    . ILE A 1 309 ? -12.228 -0.312  24.430 1.00 11.50 ?  275  ILE A N    1 
ATOM   4009  C CA   . ILE A 1 309 ? -12.468 0.392   25.697 1.00 10.72 ?  275  ILE A CA   1 
ATOM   4010  C C    . ILE A 1 309 ? -11.145 0.991   26.124 1.00 12.42 ?  275  ILE A C    1 
ATOM   4011  O O    . ILE A 1 309 ? -10.134 0.292   26.187 1.00 12.45 ?  275  ILE A O    1 
ATOM   4012  C CB   . ILE A 1 309 ? -12.970 -0.553  26.807 1.00 12.35 ?  275  ILE A CB   1 
ATOM   4013  C CG1  . ILE A 1 309 ? -14.389 -1.018  26.477 1.00 14.58 ?  275  ILE A CG1  1 
ATOM   4014  C CG2  . ILE A 1 309 ? -12.888 0.094   28.195 1.00 12.99 ?  275  ILE A CG2  1 
ATOM   4015  C CD1  . ILE A 1 309 ? -15.438 0.089   26.486 1.00 15.88 ?  275  ILE A CD1  1 
ATOM   4016  H H    . ILE A 1 309 ? -11.589 -0.886  24.472 1.00 13.80 ?  275  ILE A H    1 
ATOM   4017  H HA   . ILE A 1 309 ? -13.131 1.086   25.559 1.00 12.86 ?  275  ILE A HA   1 
ATOM   4018  H HB   . ILE A 1 309 ? -12.387 -1.327  26.836 1.00 14.82 ?  275  ILE A HB   1 
ATOM   4019  H HG12 . ILE A 1 309 ? -14.386 -1.411  25.590 1.00 17.49 ?  275  ILE A HG12 1 
ATOM   4020  H HG13 . ILE A 1 309 ? -14.657 -1.680  27.132 1.00 17.49 ?  275  ILE A HG13 1 
ATOM   4021  H HG21 . ILE A 1 309 ? -13.357 -0.466  28.833 1.00 15.59 ?  275  ILE A HG21 1 
ATOM   4022  H HG22 . ILE A 1 309 ? -11.956 0.177   28.451 1.00 15.59 ?  275  ILE A HG22 1 
ATOM   4023  H HG23 . ILE A 1 309 ? -13.300 0.971   28.160 1.00 15.59 ?  275  ILE A HG23 1 
ATOM   4024  H HD11 . ILE A 1 309 ? -16.309 -0.301  26.311 1.00 19.06 ?  275  ILE A HD11 1 
ATOM   4025  H HD12 . ILE A 1 309 ? -15.436 0.518   27.356 1.00 19.06 ?  275  ILE A HD12 1 
ATOM   4026  H HD13 . ILE A 1 309 ? -15.221 0.736   25.797 1.00 19.06 ?  275  ILE A HD13 1 
ATOM   4027  N N    . THR A 1 310 ? -11.128 2.302   26.423 1.00 11.03 ?  276  THR A N    1 
ATOM   4028  C CA   . THR A 1 310 ? -9.946  2.931   27.018 1.00 10.49 ?  276  THR A CA   1 
ATOM   4029  C C    . THR A 1 310 ? -10.385 3.521   28.350 1.00 11.62 ?  276  THR A C    1 
ATOM   4030  O O    . THR A 1 310 ? -10.986 4.616   28.409 1.00 12.09 ?  276  THR A O    1 
ATOM   4031  C CB   . THR A 1 310 ? -9.281  3.967   26.094 1.00 12.10 ?  276  THR A CB   1 
ATOM   4032  O OG1  . THR A 1 310 ? -10.147 5.071   25.847 1.00 12.13 ?  276  THR A OG1  1 
ATOM   4033  C CG2  . THR A 1 310 ? -8.922  3.398   24.773 1.00 12.59 ?  276  THR A CG2  1 
ATOM   4034  H H    . THR A 1 310 ? -11.787 2.838   26.289 1.00 13.24 ?  276  THR A H    1 
ATOM   4035  H HA   . THR A 1 310 ? -9.270  2.254   27.178 1.00 12.59 ?  276  THR A HA   1 
ATOM   4036  H HB   . THR A 1 310 ? -8.476  4.260   26.550 1.00 14.52 ?  276  THR A HB   1 
ATOM   4037  H HG1  . THR A 1 310 ? -10.422 5.389   26.574 1.00 14.56 ?  276  THR A HG1  1 
ATOM   4038  H HG21 . THR A 1 310 ? -8.409  4.044   24.262 1.00 15.11 ?  276  THR A HG21 1 
ATOM   4039  H HG22 . THR A 1 310 ? -8.389  2.596   24.891 1.00 15.11 ?  276  THR A HG22 1 
ATOM   4040  H HG23 . THR A 1 310 ? -9.725  3.171   24.279 1.00 15.11 ?  276  THR A HG23 1 
ATOM   4041  N N    . MET A 1 311 ? -10.117 2.792   29.415 1.00 11.99 ?  277  MET A N    1 
ATOM   4042  C CA   . MET A 1 311 ? -10.558 3.181   30.752 1.00 11.16 ?  277  MET A CA   1 
ATOM   4043  C C    . MET A 1 311 ? -9.515  4.056   31.397 1.00 12.34 ?  277  MET A C    1 
ATOM   4044  O O    . MET A 1 311 ? -8.388  3.633   31.595 1.00 13.00 ?  277  MET A O    1 
ATOM   4045  C CB   . MET A 1 311 ? -10.836 1.937   31.609 1.00 12.88 ?  277  MET A CB   1 
ATOM   4046  C CG   . MET A 1 311 ? -11.461 2.263   32.953 1.00 12.76 ?  277  MET A CG   1 
ATOM   4047  S SD   . MET A 1 311 ? -11.698 0.869   34.047 1.00 14.28 ?  277  MET A SD   1 
ATOM   4048  C CE   . MET A 1 311 ? -13.109 0.118   33.336 1.00 16.49 ?  277  MET A CE   1 
ATOM   4049  H H    . MET A 1 311 ? -9.675  2.055   29.396 1.00 14.39 ?  277  MET A H    1 
ATOM   4050  H HA   . MET A 1 311 ? -11.383 3.686   30.678 1.00 13.39 ?  277  MET A HA   1 
ATOM   4051  H HB2  . MET A 1 311 ? -11.447 1.356   31.129 1.00 15.45 ?  277  MET A HB2  1 
ATOM   4052  H HB3  . MET A 1 311 ? -9.999  1.476   31.773 1.00 15.45 ?  277  MET A HB3  1 
ATOM   4053  H HG2  . MET A 1 311 ? -10.886 2.895   33.412 1.00 15.31 ?  277  MET A HG2  1 
ATOM   4054  H HG3  . MET A 1 311 ? -12.332 2.659   32.797 1.00 15.31 ?  277  MET A HG3  1 
ATOM   4055  H HE1  . MET A 1 311 ? -13.342 -0.669  33.854 1.00 19.78 ?  277  MET A HE1  1 
ATOM   4056  H HE2  . MET A 1 311 ? -13.844 0.752   33.349 1.00 19.78 ?  277  MET A HE2  1 
ATOM   4057  H HE3  . MET A 1 311 ? -12.906 -0.135  32.422 1.00 19.78 ?  277  MET A HE3  1 
ATOM   4058  N N    . THR A 1 312 ? -9.903  5.295   31.697 1.00 12.07 ?  278  THR A N    1 
ATOM   4059  C CA   . THR A 1 312 ? -9.039  6.190   32.452 1.00 11.80 ?  278  THR A CA   1 
ATOM   4060  C C    . THR A 1 312 ? -9.558  6.261   33.886 1.00 11.38 ?  278  THR A C    1 
ATOM   4061  O O    . THR A 1 312 ? -10.753 6.325   34.119 1.00 12.74 ?  278  THR A O    1 
ATOM   4062  C CB   . THR A 1 312 ? -8.927  7.585   31.825 1.00 11.45 ?  278  THR A CB   1 
ATOM   4063  O OG1  . THR A 1 312 ? -10.125 8.343   31.977 1.00 12.50 ?  278  THR A OG1  1 
ATOM   4064  C CG2  . THR A 1 312 ? -8.550  7.456   30.367 1.00 12.65 ?  278  THR A CG2  1 
ATOM   4065  H H    . THR A 1 312 ? -10.660 5.636   31.473 1.00 14.49 ?  278  THR A H    1 
ATOM   4066  H HA   . THR A 1 312 ? -8.133  5.843   32.458 1.00 14.15 ?  278  THR A HA   1 
ATOM   4067  H HB   . THR A 1 312 ? -8.233  8.082   32.286 1.00 13.74 ?  278  THR A HB   1 
ATOM   4068  H HG1  . THR A 1 312 ? -10.660 8.162   31.355 1.00 15.00 ?  278  THR A HG1  1 
ATOM   4069  H HG21 . THR A 1 312 ? -8.345  8.329   29.999 1.00 15.18 ?  278  THR A HG21 1 
ATOM   4070  H HG22 . THR A 1 312 ? -7.772  6.884   30.274 1.00 15.18 ?  278  THR A HG22 1 
ATOM   4071  H HG23 . THR A 1 312 ? -9.287  7.069   29.867 1.00 15.18 ?  278  THR A HG23 1 
ATOM   4072  N N    . LEU A 1 313 ? -8.617  6.240   34.828 1.00 12.16 ?  279  LEU A N    1 
ATOM   4073  C CA   . LEU A 1 313 ? -8.931  6.319   36.256 1.00 12.91 ?  279  LEU A CA   1 
ATOM   4074  C C    . LEU A 1 313 ? -7.867  7.205   36.880 1.00 13.95 ?  279  LEU A C    1 
ATOM   4075  O O    . LEU A 1 313 ? -6.683  7.020   36.662 1.00 13.85 ?  279  LEU A O    1 
ATOM   4076  C CB   . LEU A 1 313 ? -8.914  4.935   36.916 1.00 14.75 ?  279  LEU A CB   1 
ATOM   4077  C CG   . LEU A 1 313 ? -10.049 4.025   36.438 1.00 13.84 ?  279  LEU A CG   1 
ATOM   4078  C CD1  . LEU A 1 313 ? -9.769  2.554   36.808 1.00 15.39 ?  279  LEU A CD1  1 
ATOM   4079  C CD2  . LEU A 1 313 ? -11.346 4.440   37.052 1.00 17.86 ?  279  LEU A CD2  1 
ATOM   4080  H H    . LEU A 1 313 ? -7.775  6.179   34.664 1.00 14.59 ?  279  LEU A H    1 
ATOM   4081  H HA   . LEU A 1 313 ? -9.813  6.696   36.397 1.00 15.50 ?  279  LEU A HA   1 
ATOM   4082  H HB2  . LEU A 1 313 ? -8.073  4.498   36.708 1.00 17.69 ?  279  LEU A HB2  1 
ATOM   4083  H HB3  . LEU A 1 313 ? -9.002  5.044   37.876 1.00 17.69 ?  279  LEU A HB3  1 
ATOM   4084  H HG   . LEU A 1 313 ? -10.111 4.100   35.473 1.00 16.61 ?  279  LEU A HG   1 
ATOM   4085  H HD11 . LEU A 1 313 ? -10.527 2.012   36.540 1.00 18.46 ?  279  LEU A HD11 1 
ATOM   4086  H HD12 . LEU A 1 313 ? -8.970  2.258   36.345 1.00 18.46 ?  279  LEU A HD12 1 
ATOM   4087  H HD13 . LEU A 1 313 ? -9.639  2.489   37.767 1.00 18.46 ?  279  LEU A HD13 1 
ATOM   4088  H HD21 . LEU A 1 313 ? -12.047 3.846   36.742 1.00 21.44 ?  279  LEU A HD21 1 
ATOM   4089  H HD22 . LEU A 1 313 ? -11.270 4.387   38.018 1.00 21.44 ?  279  LEU A HD22 1 
ATOM   4090  H HD23 . LEU A 1 313 ? -11.544 5.352   36.786 1.00 21.44 ?  279  LEU A HD23 1 
ATOM   4091  N N    . GLY A 1 314 ? -8.302  8.202   37.642 1.00 13.79 ?  280  GLY A N    1 
ATOM   4092  C CA   . GLY A 1 314 ? -7.375  9.140   38.251 1.00 14.28 ?  280  GLY A CA   1 
ATOM   4093  C C    . GLY A 1 314 ? -6.716  8.614   39.507 1.00 14.96 ?  280  GLY A C    1 
ATOM   4094  O O    . GLY A 1 314 ? -7.383  8.028   40.377 1.00 17.59 ?  280  GLY A O    1 
ATOM   4095  H H    . GLY A 1 314 ? -9.129  8.356   37.820 1.00 16.55 ?  280  GLY A H    1 
ATOM   4096  H HA2  . GLY A 1 314 ? -6.677  9.354   37.613 1.00 17.13 ?  280  GLY A HA2  1 
ATOM   4097  H HA3  . GLY A 1 314 ? -7.853  9.952   38.480 1.00 17.13 ?  280  GLY A HA3  1 
ATOM   4098  N N    . LEU A 1 315 ? -5.415  8.814   39.593 1.00 16.05 ?  281  LEU A N    1 
ATOM   4099  C CA   . LEU A 1 315 ? -4.606  8.647   40.793 1.00 16.99 ?  281  LEU A CA   1 
ATOM   4100  C C    . LEU A 1 315 ? -4.296  9.991   41.457 1.00 26.90 ?  281  LEU A C    1 
ATOM   4101  O O    . LEU A 1 315 ? -3.521  10.030  42.428 1.00 25.79 ?  281  LEU A O    1 
ATOM   4102  C CB   . LEU A 1 315 ? -3.253  8.038   40.446 1.00 21.64 ?  281  LEU A CB   1 
ATOM   4103  C CG   . LEU A 1 315 ? -3.188  6.549   40.116 1.00 21.32 ?  281  LEU A CG   1 
ATOM   4104  C CD1  . LEU A 1 315 ? -1.864  6.158   39.512 1.00 34.63 ?  281  LEU A CD1  1 
ATOM   4105  C CD2  . LEU A 1 315 ? -3.432  5.778   41.360 1.00 22.01 ?  281  LEU A CD2  1 
ATOM   4106  H H    . LEU A 1 315 ? -4.939  9.066   38.922 1.00 19.26 ?  281  LEU A H    1 
ATOM   4107  H HA   . LEU A 1 315 ? -5.088  8.059   41.395 1.00 20.39 ?  281  LEU A HA   1 
ATOM   4108  H HB2  . LEU A 1 315 ? -2.910  8.508   39.670 1.00 25.97 ?  281  LEU A HB2  1 
ATOM   4109  H HB3  . LEU A 1 315 ? -2.665  8.178   41.205 1.00 25.97 ?  281  LEU A HB3  1 
ATOM   4110  H HG   . LEU A 1 315 ? -3.866  6.341   39.454 1.00 25.58 ?  281  LEU A HG   1 
ATOM   4111  H HD11 . LEU A 1 315 ? -1.874  5.208   39.318 1.00 41.56 ?  281  LEU A HD11 1 
ATOM   4112  H HD12 . LEU A 1 315 ? -1.729  6.662   38.695 1.00 41.56 ?  281  LEU A HD12 1 
ATOM   4113  H HD13 . LEU A 1 315 ? -1.157  6.360   40.145 1.00 41.56 ?  281  LEU A HD13 1 
ATOM   4114  H HD21 . LEU A 1 315 ? -3.387  4.830   41.158 1.00 26.41 ?  281  LEU A HD21 1 
ATOM   4115  H HD22 . LEU A 1 315 ? -2.753  6.009   42.013 1.00 26.41 ?  281  LEU A HD22 1 
ATOM   4116  H HD23 . LEU A 1 315 ? -4.311  6.001   41.704 1.00 26.41 ?  281  LEU A HD23 1 
ATOM   4117  N N    . GLY A 1 316 ? -4.836  11.098  40.944 1.00 28.71 ?  282  GLY A N    1 
ATOM   4118  C CA   . GLY A 1 316 ? -4.418  12.409  41.439 1.00 33.21 ?  282  GLY A CA   1 
ATOM   4119  C C    . GLY A 1 316 ? -4.595  12.570  42.938 1.00 29.64 ?  282  GLY A C    1 
ATOM   4120  O O    . GLY A 1 316 ? -3.749  13.178  43.610 1.00 32.55 ?  282  GLY A O    1 
ATOM   4121  H H    . GLY A 1 316 ? -5.432  11.117  40.325 1.00 34.45 ?  282  GLY A H    1 
ATOM   4122  H HA2  . GLY A 1 316 ? -3.481  12.543  41.230 1.00 39.86 ?  282  GLY A HA2  1 
ATOM   4123  H HA3  . GLY A 1 316 ? -4.942  13.096  40.998 1.00 39.86 ?  282  GLY A HA3  1 
ATOM   4124  N N    . GLU A 1 317 ? -5.691  12.035  43.484 1.00 31.35 ?  283  GLU A N    1 
ATOM   4125  C CA   . GLU A 1 317 ? -5.973  12.192  44.908 1.00 40.77 ?  283  GLU A CA   1 
ATOM   4126  C C    . GLU A 1 317 ? -5.069  11.319  45.770 1.00 41.82 ?  283  GLU A C    1 
ATOM   4127  O O    . GLU A 1 317 ? -4.702  11.715  46.879 1.00 42.25 ?  283  GLU A O    1 
ATOM   4128  C CB   . GLU A 1 317 ? -7.446  11.875  45.188 1.00 44.16 ?  283  GLU A CB   1 
ATOM   4129  C CG   . GLU A 1 317 ? -8.425  12.925  44.635 1.00 48.04 ?  283  GLU A CG   1 
ATOM   4130  C CD   . GLU A 1 317 ? -9.847  12.387  44.481 1.00 61.85 ?  283  GLU A CD   1 
ATOM   4131  O OE1  . GLU A 1 317 ? -10.018 11.149  44.395 1.00 66.71 ?  283  GLU A OE1  1 
ATOM   4132  O OE2  . GLU A 1 317 ? -10.794 13.204  44.455 1.00 58.30 ?  283  GLU A OE2  1 
ATOM   4133  H H    . GLU A 1 317 ? -6.281  11.580  43.054 1.00 37.62 ?  283  GLU A H    1 
ATOM   4134  H HA   . GLU A 1 317 ? -5.811  13.116  45.154 1.00 48.93 ?  283  GLU A HA   1 
ATOM   4135  H HB2  . GLU A 1 317 ? -7.664  11.023  44.780 1.00 52.99 ?  283  GLU A HB2  1 
ATOM   4136  H HB3  . GLU A 1 317 ? -7.576  11.826  46.148 1.00 52.99 ?  283  GLU A HB3  1 
ATOM   4137  H HG2  . GLU A 1 317 ? -8.455  13.680  45.242 1.00 57.65 ?  283  GLU A HG2  1 
ATOM   4138  H HG3  . GLU A 1 317 ? -8.118  13.213  43.761 1.00 57.65 ?  283  GLU A HG3  1 
ATOM   4139  N N    . ALA A 1 318 ? -4.702  10.135  45.286 1.00 29.46 ?  284  ALA A N    1 
ATOM   4140  C CA   . ALA A 1 318 ? -3.784  9.274   46.028 1.00 26.83 ?  284  ALA A CA   1 
ATOM   4141  C C    . ALA A 1 318 ? -2.339  9.762   45.957 1.00 30.84 ?  284  ALA A C    1 
ATOM   4142  O O    . ALA A 1 318 ? -1.528  9.402   46.819 1.00 33.83 ?  284  ALA A O    1 
ATOM   4143  C CB   . ALA A 1 318 ? -3.850  7.867   45.444 1.00 28.34 ?  284  ALA A CB   1 
ATOM   4144  H H    . ALA A 1 318 ? -4.968  9.808   44.536 1.00 35.35 ?  284  ALA A H    1 
ATOM   4145  H HA   . ALA A 1 318 ? -4.053  9.257   46.959 1.00 32.20 ?  284  ALA A HA   1 
ATOM   4146  H HB1  . ALA A 1 318 ? -3.209  7.303   45.906 1.00 34.01 ?  284  ALA A HB1  1 
ATOM   4147  H HB2  . ALA A 1 318 ? -4.746  7.516   45.564 1.00 34.01 ?  284  ALA A HB2  1 
ATOM   4148  H HB3  . ALA A 1 318 ? -3.634  7.907   44.499 1.00 34.01 ?  284  ALA A HB3  1 
ATOM   4149  N N    . ILE A 1 319 ? -2.005  10.554  44.945 1.00 21.97 ?  285  ILE A N    1 
ATOM   4150  C CA   . ILE A 1 319 ? -0.666  11.105  44.804 1.00 24.37 ?  285  ILE A CA   1 
ATOM   4151  C C    . ILE A 1 319 ? -0.513  12.437  45.535 1.00 33.02 ?  285  ILE A C    1 
ATOM   4152  O O    . ILE A 1 319 ? 0.569   12.732  46.051 1.00 39.11 ?  285  ILE A O    1 
ATOM   4153  C CB   . ILE A 1 319 ? -0.336  11.255  43.313 1.00 31.44 ?  285  ILE A CB   1 
ATOM   4154  C CG1  . ILE A 1 319 ? -0.014  9.887   42.700 1.00 32.81 ?  285  ILE A CG1  1 
ATOM   4155  C CG2  . ILE A 1 319 ? 0.838   12.230  43.128 1.00 36.20 ?  285  ILE A CG2  1 
ATOM   4156  C CD1  . ILE A 1 319 ? 0.048   9.918   41.174 1.00 38.48 ?  285  ILE A CD1  1 
ATOM   4157  H H    . ILE A 1 319 ? -2.543  10.790  44.318 1.00 26.37 ?  285  ILE A H    1 
ATOM   4158  H HA   . ILE A 1 319 ? -0.029  10.493  45.203 1.00 29.25 ?  285  ILE A HA   1 
ATOM   4159  H HB   . ILE A 1 319 ? -1.110  11.616  42.855 1.00 37.73 ?  285  ILE A HB   1 
ATOM   4160  H HG12 . ILE A 1 319 ? 0.848   9.589   43.029 1.00 39.37 ?  285  ILE A HG12 1 
ATOM   4161  H HG13 . ILE A 1 319 ? -0.704  9.256   42.959 1.00 39.37 ?  285  ILE A HG13 1 
ATOM   4162  H HG21 . ILE A 1 319 ? 1.194   12.129  42.232 1.00 43.44 ?  285  ILE A HG21 1 
ATOM   4163  H HG22 . ILE A 1 319 ? 0.518   13.137  43.256 1.00 43.44 ?  285  ILE A HG22 1 
ATOM   4164  H HG23 . ILE A 1 319 ? 1.525   12.026  43.782 1.00 43.44 ?  285  ILE A HG23 1 
ATOM   4165  H HD11 . ILE A 1 319 ? 0.053   9.008   40.839 1.00 46.17 ?  285  ILE A HD11 1 
ATOM   4166  H HD12 . ILE A 1 319 ? -0.729  10.391  40.836 1.00 46.17 ?  285  ILE A HD12 1 
ATOM   4167  H HD13 . ILE A 1 319 ? 0.858   10.376  40.900 1.00 46.17 ?  285  ILE A HD13 1 
ATOM   4168  N N    . ASP A 1 320 ? -1.557  13.250  45.592 1.00 27.07 ?  286  ASP A N    1 
ATOM   4169  C CA   . ASP A 1 320 ? -1.399  14.597  46.125 1.00 23.64 ?  286  ASP A CA   1 
ATOM   4170  C C    . ASP A 1 320 ? -0.985  14.534  47.593 1.00 33.34 ?  286  ASP A C    1 
ATOM   4171  O O    . ASP A 1 320 ? -1.503  13.735  48.375 1.00 30.06 ?  286  ASP A O    1 
ATOM   4172  C CB   . ASP A 1 320 ? -2.695  15.391  45.961 1.00 28.09 ?  286  ASP A CB   1 
ATOM   4173  C CG   . ASP A 1 320 ? -2.564  16.809  46.485 1.00 50.08 ?  286  ASP A CG   1 
ATOM   4174  O OD1  . ASP A 1 320 ? -2.774  17.014  47.698 1.00 43.93 ?  286  ASP A OD1  1 
ATOM   4175  O OD2  . ASP A 1 320 ? -2.233  17.713  45.681 1.00 46.33 ?  286  ASP A OD2  1 
ATOM   4176  H H    . ASP A 1 320 ? -2.353  13.052  45.333 1.00 32.48 ?  286  ASP A H    1 
ATOM   4177  H HA   . ASP A 1 320 ? -0.706  15.064  45.632 1.00 28.36 ?  286  ASP A HA   1 
ATOM   4178  H HB2  . ASP A 1 320 ? -2.925  15.436  45.020 1.00 33.70 ?  286  ASP A HB2  1 
ATOM   4179  H HB3  . ASP A 1 320 ? -3.404  14.950  46.455 1.00 33.70 ?  286  ASP A HB3  1 
ATOM   4180  N N    . ASN A 1 321 ? -0.035  15.392  47.970 1.00 28.40 ?  287  ASN A N    1 
ATOM   4181  C CA   . ASN A 1 321 ? 0.549   15.394  49.306 1.00 33.49 ?  287  ASN A CA   1 
ATOM   4182  C C    . ASN A 1 321 ? 0.566   16.800  49.891 1.00 37.79 ?  287  ASN A C    1 
ATOM   4183  O O    . ASN A 1 321 ? 1.426   17.123  50.717 1.00 31.92 ?  287  ASN A O    1 
ATOM   4184  C CB   . ASN A 1 321 ? 1.953   14.789  49.291 1.00 33.76 ?  287  ASN A CB   1 
ATOM   4185  H H    . ASN A 1 321 ? 0.295   15.997  47.454 1.00 34.08 ?  287  ASN A H    1 
ATOM   4186  H HA   . ASN A 1 321 ? 0.001   14.844  49.888 1.00 40.19 ?  287  ASN A HA   1 
ATOM   4187  N N    . ASN A 1 322 ? -0.389  17.639  49.486 1.00 24.70 ?  288  ASN A N    1 
ATOM   4188  C CA   . ASN A 1 322 ? -0.495  19.020  49.958 1.00 30.94 ?  288  ASN A CA   1 
ATOM   4189  C C    . ASN A 1 322 ? 0.797   19.807  49.713 1.00 26.74 ?  288  ASN A C    1 
ATOM   4190  O O    . ASN A 1 322 ? 1.255   20.545  50.593 1.00 25.18 ?  288  ASN A O    1 
ATOM   4191  C CB   . ASN A 1 322 ? -0.880  19.091  51.445 1.00 37.70 ?  288  ASN A CB   1 
ATOM   4192  C CG   . ASN A 1 322 ? -2.302  18.643  51.718 1.00 43.39 ?  288  ASN A CG   1 
ATOM   4193  O OD1  . ASN A 1 322 ? -3.211  18.902  50.927 1.00 46.81 ?  288  ASN A OD1  1 
ATOM   4194  N ND2  . ASN A 1 322 ? -2.507  17.987  52.864 1.00 35.13 ?  288  ASN A ND2  1 
ATOM   4195  H H    . ASN A 1 322 ? -1.002  17.427  48.922 1.00 29.64 ?  288  ASN A H    1 
ATOM   4196  H HA   . ASN A 1 322 ? -1.202  19.441  49.445 1.00 37.12 ?  288  ASN A HA   1 
ATOM   4197  H HB2  . ASN A 1 322 ? -0.285  18.517  51.952 1.00 45.25 ?  288  ASN A HB2  1 
ATOM   4198  H HB3  . ASN A 1 322 ? -0.794  20.009  51.748 1.00 45.25 ?  288  ASN A HB3  1 
ATOM   4199  H HD21 . ASN A 1 322 ? -1.851  17.840  53.399 1.00 42.15 ?  288  ASN A HD21 1 
ATOM   4200  H HD22 . ASN A 1 322 ? -3.297  17.711  53.066 1.00 42.15 ?  288  ASN A HD22 1 
ATOM   4201  N N    . THR A 1 323 ? 1.390   19.655  48.521 1.00 20.31 ?  289  THR A N    1 
ATOM   4202  C CA   . THR A 1 323 ? 2.513   20.489  48.090 1.00 19.18 ?  289  THR A CA   1 
ATOM   4203  C C    . THR A 1 323 ? 2.365   20.847  46.615 1.00 21.41 ?  289  THR A C    1 
ATOM   4204  O O    . THR A 1 323 ? 1.587   20.226  45.890 1.00 23.41 ?  289  THR A O    1 
ATOM   4205  C CB   . THR A 1 323 ? 3.854   19.786  48.289 1.00 18.00 ?  289  THR A CB   1 
ATOM   4206  O OG1  . THR A 1 323 ? 3.901   18.635  47.426 1.00 22.47 ?  289  THR A OG1  1 
ATOM   4207  C CG2  . THR A 1 323 ? 4.031   19.320  49.734 1.00 21.56 ?  289  THR A CG2  1 
ATOM   4208  H H    . THR A 1 323 ? 1.155   19.066  47.940 1.00 24.37 ?  289  THR A H    1 
ATOM   4209  H HA   . THR A 1 323 ? 2.497   21.307  48.611 1.00 23.02 ?  289  THR A HA   1 
ATOM   4210  H HB   . THR A 1 323 ? 4.574   20.402  48.082 1.00 21.60 ?  289  THR A HB   1 
ATOM   4211  H HG1  . THR A 1 323 ? 3.176   18.212  47.471 1.00 26.96 ?  289  THR A HG1  1 
ATOM   4212  H HG21 . THR A 1 323 ? 4.914   18.936  49.854 1.00 25.88 ?  289  THR A HG21 1 
ATOM   4213  H HG22 . THR A 1 323 ? 3.930   20.072  50.339 1.00 25.88 ?  289  THR A HG22 1 
ATOM   4214  H HG23 . THR A 1 323 ? 3.364   18.650  49.951 1.00 25.88 ?  289  THR A HG23 1 
ATOM   4215  N N    . GLY A 1 324 ? 3.112   21.869  46.163 1.00 17.22 ?  290  GLY A N    1 
ATOM   4216  C CA   . GLY A 1 324 ? 3.199   22.231  44.772 1.00 15.23 ?  290  GLY A CA   1 
ATOM   4217  C C    . GLY A 1 324 ? 2.523   23.533  44.386 1.00 15.39 ?  290  GLY A C    1 
ATOM   4218  O O    . GLY A 1 324 ? 2.724   23.975  43.249 1.00 18.17 ?  290  GLY A O    1 
ATOM   4219  H H    . GLY A 1 324 ? 3.586   22.373  46.674 1.00 20.67 ?  290  GLY A H    1 
ATOM   4220  H HA2  . GLY A 1 324 ? 4.136   22.307  44.533 1.00 18.28 ?  290  GLY A HA2  1 
ATOM   4221  H HA3  . GLY A 1 324 ? 2.795   21.524  44.245 1.00 18.28 ?  290  GLY A HA3  1 
ATOM   4222  N N    . ILE A 1 325 ? 1.758   24.141  45.278 1.00 16.29 ?  291  ILE A N    1 
ATOM   4223  C CA   . ILE A 1 325 ? 1.083   25.413  44.947 1.00 13.88 ?  291  ILE A CA   1 
ATOM   4224  C C    . ILE A 1 325 ? 1.995   26.604  45.198 1.00 14.22 ?  291  ILE A C    1 
ATOM   4225  O O    . ILE A 1 325 ? 2.211   27.423  44.298 1.00 15.08 ?  291  ILE A O    1 
ATOM   4226  C CB   . ILE A 1 325 ? -0.251  25.528  45.705 1.00 14.95 ?  291  ILE A CB   1 
ATOM   4227  C CG1  . ILE A 1 325 ? -1.165  24.346  45.358 1.00 16.42 ?  291  ILE A CG1  1 
ATOM   4228  C CG2  . ILE A 1 325 ? -0.907  26.881  45.421 1.00 14.29 ?  291  ILE A CG2  1 
ATOM   4229  C CD1  . ILE A 1 325 ? -2.570  24.376  45.927 1.00 25.89 ?  291  ILE A CD1  1 
ATOM   4230  H H    . ILE A 1 325 ? 1.608   23.852  46.073 1.00 19.54 ?  291  ILE A H    1 
ATOM   4231  H HA   . ILE A 1 325 ? 0.870   25.410  44.001 1.00 16.66 ?  291  ILE A HA   1 
ATOM   4232  H HB   . ILE A 1 325 ? -0.081  25.484  46.659 1.00 17.94 ?  291  ILE A HB   1 
ATOM   4233  H HG12 . ILE A 1 325 ? -1.253  24.309  44.393 1.00 19.71 ?  291  ILE A HG12 1 
ATOM   4234  H HG13 . ILE A 1 325 ? -0.745  23.536  45.685 1.00 19.71 ?  291  ILE A HG13 1 
ATOM   4235  H HG21 . ILE A 1 325 ? -1.743  26.936  45.910 1.00 17.14 ?  291  ILE A HG21 1 
ATOM   4236  H HG22 . ILE A 1 325 ? -0.309  27.589  45.708 1.00 17.14 ?  291  ILE A HG22 1 
ATOM   4237  H HG23 . ILE A 1 325 ? -1.076  26.957  44.468 1.00 17.14 ?  291  ILE A HG23 1 
ATOM   4238  H HD11 . ILE A 1 325 ? -3.051  23.591  45.622 1.00 31.07 ?  291  ILE A HD11 1 
ATOM   4239  H HD12 . ILE A 1 325 ? -2.518  24.376  46.896 1.00 31.07 ?  291  ILE A HD12 1 
ATOM   4240  H HD13 . ILE A 1 325 ? -3.018  25.179  45.620 1.00 31.07 ?  291  ILE A HD13 1 
ATOM   4241  N N    . ASP A 1 326 ? 2.536   26.720  46.412 1.00 14.31 ?  292  ASP A N    1 
ATOM   4242  C CA   . ASP A 1 326 ? 3.465   27.785  46.789 1.00 12.45 ?  292  ASP A CA   1 
ATOM   4243  C C    . ASP A 1 326 ? 4.812   27.228  47.234 1.00 16.06 ?  292  ASP A C    1 
ATOM   4244  O O    . ASP A 1 326 ? 5.658   27.964  47.742 1.00 15.43 ?  292  ASP A O    1 
ATOM   4245  C CB   . ASP A 1 326 ? 2.869   28.623  47.907 1.00 14.11 ?  292  ASP A CB   1 
ATOM   4246  C CG   . ASP A 1 326 ? 1.645   29.417  47.454 1.00 12.77 ?  292  ASP A CG   1 
ATOM   4247  O OD1  . ASP A 1 326 ? 1.833   30.260  46.553 1.00 13.59 ?  292  ASP A OD1  1 
ATOM   4248  O OD2  . ASP A 1 326 ? 0.553   29.211  48.015 1.00 13.73 ?  292  ASP A OD2  1 
ATOM   4249  H H    . ASP A 1 326 ? 2.375   26.174  47.057 1.00 17.17 ?  292  ASP A H    1 
ATOM   4250  H HA   . ASP A 1 326 ? 3.610   28.363  46.023 1.00 14.94 ?  292  ASP A HA   1 
ATOM   4251  H HB2  . ASP A 1 326 ? 2.596   28.037  48.631 1.00 16.93 ?  292  ASP A HB2  1 
ATOM   4252  H HB3  . ASP A 1 326 ? 3.536   29.252  48.223 1.00 16.93 ?  292  ASP A HB3  1 
ATOM   4253  N N    . ASP A 1 327 ? 5.051   25.936  47.009 1.00 14.59 ?  293  ASP A N    1 
ATOM   4254  C CA   . ASP A 1 327 ? 6.300   25.264  47.366 1.00 14.45 ?  293  ASP A CA   1 
ATOM   4255  C C    . ASP A 1 327 ? 6.581   24.219  46.285 1.00 15.44 ?  293  ASP A C    1 
ATOM   4256  O O    . ASP A 1 327 ? 5.779   23.985  45.375 1.00 15.07 ?  293  ASP A O    1 
ATOM   4257  C CB   . ASP A 1 327 ? 6.283   24.702  48.794 1.00 15.67 ?  293  ASP A CB   1 
ATOM   4258  C CG   . ASP A 1 327 ? 5.083   23.838  49.118 1.00 16.13 ?  293  ASP A CG   1 
ATOM   4259  O OD1  . ASP A 1 327 ? 4.476   23.273  48.177 1.00 16.96 ?  293  ASP A OD1  1 
ATOM   4260  O OD2  . ASP A 1 327 ? 4.719   23.705  50.313 1.00 17.45 ?  293  ASP A OD2  1 
ATOM   4261  H H    . ASP A 1 327 ? 4.484   25.408  46.637 1.00 17.50 ?  293  ASP A H    1 
ATOM   4262  H HA   . ASP A 1 327 ? 7.043   25.888  47.363 1.00 17.34 ?  293  ASP A HA   1 
ATOM   4263  H HB2  . ASP A 1 327 ? 7.076   24.159  48.922 1.00 18.81 ?  293  ASP A HB2  1 
ATOM   4264  H HB3  . ASP A 1 327 ? 6.285   25.444  49.419 1.00 18.81 ?  293  ASP A HB3  1 
ATOM   4265  N N    . GLN A 1 328 ? 7.772   23.631  46.337 1.00 15.34 ?  294  GLN A N    1 
ATOM   4266  C CA   . GLN A 1 328 ? 8.080   22.537  45.422 1.00 15.32 ?  294  GLN A CA   1 
ATOM   4267  C C    . GLN A 1 328 ? 7.129   21.379  45.678 1.00 15.14 ?  294  GLN A C    1 
ATOM   4268  O O    . GLN A 1 328 ? 6.812   21.026  46.815 1.00 17.69 ?  294  GLN A O    1 
ATOM   4269  C CB   . GLN A 1 328 ? 9.523   22.089  45.650 1.00 19.75 ?  294  GLN A CB   1 
ATOM   4270  C CG   . GLN A 1 328 ? 9.886   20.708  45.057 1.00 25.63 ?  294  GLN A CG   1 
ATOM   4271  C CD   . GLN A 1 328 ? 11.363  20.396  45.197 1.00 23.75 ?  294  GLN A CD   1 
ATOM   4272  O OE1  . GLN A 1 328 ? 12.048  20.971  46.036 1.00 27.13 ?  294  GLN A OE1  1 
ATOM   4273  N NE2  . GLN A 1 328 ? 11.851  19.475  44.371 1.00 34.34 ?  294  GLN A NE2  1 
ATOM   4274  H H    . GLN A 1 328 ? 8.405   23.842  46.880 1.00 18.41 ?  294  GLN A H    1 
ATOM   4275  H HA   . GLN A 1 328 ? 7.984   22.822  44.500 1.00 18.39 ?  294  GLN A HA   1 
ATOM   4276  H HB2  . GLN A 1 328 ? 10.115  22.742  45.245 1.00 23.70 ?  294  GLN A HB2  1 
ATOM   4277  H HB3  . GLN A 1 328 ? 9.683   22.044  46.606 1.00 23.70 ?  294  GLN A HB3  1 
ATOM   4278  H HG2  . GLN A 1 328 ? 9.386   20.020  45.523 1.00 30.76 ?  294  GLN A HG2  1 
ATOM   4279  H HG3  . GLN A 1 328 ? 9.664   20.698  44.113 1.00 30.76 ?  294  GLN A HG3  1 
ATOM   4280  H HE21 . GLN A 1 328 ? 11.335  19.094  43.799 1.00 41.20 ?  294  GLN A HE21 1 
ATOM   4281  H HE22 . GLN A 1 328 ? 12.683  19.261  44.409 1.00 41.20 ?  294  GLN A HE22 1 
ATOM   4282  N N    . ARG A 1 329 ? 6.620   20.808  44.578 1.00 18.27 ?  295  ARG A N    1 
ATOM   4283  C CA   . ARG A 1 329 ? 5.829   19.596  44.689 1.00 18.96 ?  295  ARG A CA   1 
ATOM   4284  C C    . ARG A 1 329 ? 6.727   18.429  45.111 1.00 18.27 ?  295  ARG A C    1 
ATOM   4285  O O    . ARG A 1 329 ? 7.720   18.147  44.436 1.00 20.93 ?  295  ARG A O    1 
ATOM   4286  C CB   . ARG A 1 329 ? 5.147   19.320  43.351 1.00 21.25 ?  295  ARG A CB   1 
ATOM   4287  C CG   . ARG A 1 329 ? 4.165   18.165  43.411 1.00 20.83 ?  295  ARG A CG   1 
ATOM   4288  C CD   . ARG A 1 329 ? 3.733   17.741  41.998 1.00 26.19 ?  295  ARG A CD   1 
ATOM   4289  N NE   . ARG A 1 329 ? 2.765   16.662  42.086 1.00 26.62 ?  295  ARG A NE   1 
ATOM   4290  C CZ   . ARG A 1 329 ? 2.060   16.209  41.052 1.00 29.79 ?  295  ARG A CZ   1 
ATOM   4291  N NH1  . ARG A 1 329 ? 2.232   16.702  39.831 1.00 33.52 ?  295  ARG A NH1  1 
ATOM   4292  N NH2  . ARG A 1 329 ? 1.180   15.236  41.251 1.00 28.47 ?  295  ARG A NH2  1 
ATOM   4293  H H    . ARG A 1 329 ? 6.722   21.103  43.777 1.00 21.92 ?  295  ARG A H    1 
ATOM   4294  H HA   . ARG A 1 329 ? 5.143   19.699  45.367 1.00 22.75 ?  295  ARG A HA   1 
ATOM   4295  H HB2  . ARG A 1 329 ? 4.659   20.112  43.076 1.00 25.49 ?  295  ARG A HB2  1 
ATOM   4296  H HB3  . ARG A 1 329 ? 5.824   19.102  42.691 1.00 25.49 ?  295  ARG A HB3  1 
ATOM   4297  H HG2  . ARG A 1 329 ? 4.585   17.406  43.845 1.00 25.00 ?  295  ARG A HG2  1 
ATOM   4298  H HG3  . ARG A 1 329 ? 3.376   18.436  43.906 1.00 25.00 ?  295  ARG A HG3  1 
ATOM   4299  H HD2  . ARG A 1 329 ? 3.322   18.492  41.542 1.00 31.42 ?  295  ARG A HD2  1 
ATOM   4300  H HD3  . ARG A 1 329 ? 4.504   17.429  41.499 1.00 31.42 ?  295  ARG A HD3  1 
ATOM   4301  H HE   . ARG A 1 329 ? 2.640   16.293  42.853 1.00 31.94 ?  295  ARG A HE   1 
ATOM   4302  H HH11 . ARG A 1 329 ? 2.809   17.325  39.696 1.00 40.22 ?  295  ARG A HH11 1 
ATOM   4303  H HH12 . ARG A 1 329 ? 1.768   16.397  39.175 1.00 40.22 ?  295  ARG A HH12 1 
ATOM   4304  H HH21 . ARG A 1 329 ? 1.073   14.908  42.039 1.00 34.16 ?  295  ARG A HH21 1 
ATOM   4305  H HH22 . ARG A 1 329 ? 0.718   14.933  40.593 1.00 34.16 ?  295  ARG A HH22 1 
ATOM   4306  N N    . GLU A 1 330 ? 6.372   17.793  46.222 1.00 22.42 ?  296  GLU A N    1 
ATOM   4307  C CA   . GLU A 1 330 ? 7.205   16.732  46.771 1.00 21.73 ?  296  GLU A CA   1 
ATOM   4308  C C    . GLU A 1 330 ? 7.240   15.555  45.804 1.00 29.65 ?  296  GLU A C    1 
ATOM   4309  O O    . GLU A 1 330 ? 6.211   15.165  45.260 1.00 25.73 ?  296  GLU A O    1 
ATOM   4310  C CB   . GLU A 1 330 ? 6.647   16.303  48.125 1.00 35.91 ?  296  GLU A CB   1 
ATOM   4311  H H    . GLU A 1 330 ? 5.658   17.955  46.673 1.00 26.91 ?  296  GLU A H    1 
ATOM   4312  H HA   . GLU A 1 330 ? 8.115   17.044  46.899 1.00 26.08 ?  296  GLU A HA   1 
ATOM   4313  N N    . ASP A 1 331 ? 8.439   15.015  45.576 1.00 31.42 ?  297  ASP A N    1 
ATOM   4314  C CA   . ASP A 1 331 ? 8.580   13.848  44.721 1.00 34.71 ?  297  ASP A CA   1 
ATOM   4315  C C    . ASP A 1 331 ? 7.733   12.702  45.258 1.00 32.26 ?  297  ASP A C    1 
ATOM   4316  O O    . ASP A 1 331 ? 7.696   12.435  46.466 1.00 32.12 ?  297  ASP A O    1 
ATOM   4317  C CB   . ASP A 1 331 ? 10.048  13.414  44.668 1.00 46.29 ?  297  ASP A CB   1 
ATOM   4318  C CG   . ASP A 1 331 ? 10.955  14.474  44.058 1.00 58.80 ?  297  ASP A CG   1 
ATOM   4319  O OD1  . ASP A 1 331 ? 10.437  15.503  43.568 1.00 62.13 ?  297  ASP A OD1  1 
ATOM   4320  O OD2  . ASP A 1 331 ? 12.190  14.278  44.077 1.00 62.37 ?  297  ASP A OD2  1 
ATOM   4321  H H    . ASP A 1 331 ? 9.179   15.307  45.904 1.00 37.70 ?  297  ASP A H    1 
ATOM   4322  H HA   . ASP A 1 331 ? 8.286   14.065  43.823 1.00 41.65 ?  297  ASP A HA   1 
ATOM   4323  H HB2  . ASP A 1 331 ? 10.358  13.237  45.569 1.00 55.55 ?  297  ASP A HB2  1 
ATOM   4324  H HB3  . ASP A 1 331 ? 10.121  12.611  44.128 1.00 55.55 ?  297  ASP A HB3  1 
ATOM   4325  N N    . VAL A 1 332 ? 7.043   12.034  44.351 1.00 34.36 ?  298  VAL A N    1 
ATOM   4326  C CA   . VAL A 1 332 ? 6.176   10.916  44.690 1.00 41.70 ?  298  VAL A CA   1 
ATOM   4327  C C    . VAL A 1 332 ? 7.015   9.644   44.698 1.00 28.88 ?  298  VAL A C    1 
ATOM   4328  O O    . VAL A 1 332 ? 7.787   9.393   43.762 1.00 28.57 ?  298  VAL A O    1 
ATOM   4329  C CB   . VAL A 1 332 ? 5.017   10.800  43.683 1.00 40.05 ?  298  VAL A CB   1 
ATOM   4330  H H    . VAL A 1 332 ? 7.060   12.212  43.510 1.00 41.23 ?  298  VAL A H    1 
ATOM   4331  H HA   . VAL A 1 332 ? 5.802   11.051  45.575 1.00 50.05 ?  298  VAL A HA   1 
ATOM   4332  N N    . ASP A 1 333 ? 6.887   8.870   45.773 1.00 31.58 ?  299  ASP A N    1 
ATOM   4333  C CA   . ASP A 1 333 ? 7.452   7.527   45.829 1.00 27.50 ?  299  ASP A CA   1 
ATOM   4334  C C    . ASP A 1 333 ? 6.483   6.606   45.099 1.00 24.01 ?  299  ASP A C    1 
ATOM   4335  O O    . ASP A 1 333 ? 5.460   6.185   45.646 1.00 25.84 ?  299  ASP A O    1 
ATOM   4336  C CB   . ASP A 1 333 ? 7.657   7.094   47.271 1.00 30.23 ?  299  ASP A CB   1 
ATOM   4337  C CG   . ASP A 1 333 ? 8.219   5.691   47.380 1.00 33.84 ?  299  ASP A CG   1 
ATOM   4338  O OD1  . ASP A 1 333 ? 8.585   5.114   46.327 1.00 30.10 ?  299  ASP A OD1  1 
ATOM   4339  O OD2  . ASP A 1 333 ? 8.335   5.191   48.523 1.00 41.98 ?  299  ASP A OD2  1 
ATOM   4340  H H    . ASP A 1 333 ? 6.474   9.104   46.490 1.00 37.89 ?  299  ASP A H    1 
ATOM   4341  H HA   . ASP A 1 333 ? 8.314   7.502   45.386 1.00 33.00 ?  299  ASP A HA   1 
ATOM   4342  H HB2  . ASP A 1 333 ? 8.280   7.702   47.699 1.00 36.28 ?  299  ASP A HB2  1 
ATOM   4343  H HB3  . ASP A 1 333 ? 6.804   7.113   47.732 1.00 36.28 ?  299  ASP A HB3  1 
ATOM   4344  N N    . LEU A 1 334 ? 6.820   6.286   43.858 1.00 23.81 ?  300  LEU A N    1 
ATOM   4345  C CA   . LEU A 1 334 ? 5.918   5.439   43.078 1.00 24.10 ?  300  LEU A CA   1 
ATOM   4346  C C    . LEU A 1 334 ? 5.959   3.986   43.539 1.00 25.11 ?  300  LEU A C    1 
ATOM   4347  O O    . LEU A 1 334 ? 5.157   3.179   43.042 1.00 23.93 ?  300  LEU A O    1 
ATOM   4348  C CB   . LEU A 1 334 ? 6.218   5.606   41.585 1.00 29.40 ?  300  LEU A CB   1 
ATOM   4349  C CG   . LEU A 1 334 ? 5.872   7.025   41.076 1.00 28.33 ?  300  LEU A CG   1 
ATOM   4350  C CD1  . LEU A 1 334 ? 6.222   7.187   39.615 1.00 31.70 ?  300  LEU A CD1  1 
ATOM   4351  C CD2  . LEU A 1 334 ? 4.401   7.352   41.256 1.00 29.74 ?  300  LEU A CD2  1 
ATOM   4352  H H    . LEU A 1 334 ? 7.538   6.535   43.456 1.00 28.57 ?  300  LEU A H    1 
ATOM   4353  H HA   . LEU A 1 334 ? 4.998   5.726   43.188 1.00 28.92 ?  300  LEU A HA   1 
ATOM   4354  H HB2  . LEU A 1 334 ? 7.163   5.451   41.432 1.00 35.28 ?  300  LEU A HB2  1 
ATOM   4355  H HB3  . LEU A 1 334 ? 5.690   4.967   41.082 1.00 35.28 ?  300  LEU A HB3  1 
ATOM   4356  H HG   . LEU A 1 334 ? 6.398   7.645   41.606 1.00 33.99 ?  300  LEU A HG   1 
ATOM   4357  H HD11 . LEU A 1 334 ? 6.112   8.117   39.365 1.00 38.05 ?  300  LEU A HD11 1 
ATOM   4358  H HD12 . LEU A 1 334 ? 7.143   6.914   39.479 1.00 38.05 ?  300  LEU A HD12 1 
ATOM   4359  H HD13 . LEU A 1 334 ? 5.630   6.630   39.085 1.00 38.05 ?  300  LEU A HD13 1 
ATOM   4360  H HD21 . LEU A 1 334 ? 4.196   8.163   40.765 1.00 35.69 ?  300  LEU A HD21 1 
ATOM   4361  H HD22 . LEU A 1 334 ? 3.870   6.615   40.914 1.00 35.69 ?  300  LEU A HD22 1 
ATOM   4362  H HD23 . LEU A 1 334 ? 4.219   7.480   42.200 1.00 35.69 ?  300  LEU A HD23 1 
ATOM   4363  N N    . ASN A 1 335 ? 6.841   3.654   44.484 1.00 24.81 ?  301  ASN A N    1 
ATOM   4364  C CA   . ASN A 1 335 ? 6.860   2.339   45.121 1.00 22.52 ?  301  ASN A CA   1 
ATOM   4365  C C    . ASN A 1 335 ? 6.155   2.339   46.469 1.00 23.53 ?  301  ASN A C    1 
ATOM   4366  O O    . ASN A 1 335 ? 6.144   1.300   47.150 1.00 25.57 ?  301  ASN A O    1 
ATOM   4367  C CB   . ASN A 1 335 ? 8.303   1.834   45.255 1.00 31.67 ?  301  ASN A CB   1 
ATOM   4368  C CG   . ASN A 1 335 ? 8.959   1.607   43.910 1.00 38.61 ?  301  ASN A CG   1 
ATOM   4369  O OD1  . ASN A 1 335 ? 8.643   0.648   43.204 1.00 44.69 ?  301  ASN A OD1  1 
ATOM   4370  N ND2  . ASN A 1 335 ? 9.887   2.487   43.549 1.00 49.89 ?  301  ASN A ND2  1 
ATOM   4371  H H    . ASN A 1 335 ? 7.449   4.186   44.778 1.00 29.77 ?  301  ASN A H    1 
ATOM   4372  H HA   . ASN A 1 335 ? 6.396   1.702   44.555 1.00 27.02 ?  301  ASN A HA   1 
ATOM   4373  H HB2  . ASN A 1 335 ? 8.826   2.492   45.739 1.00 38.00 ?  301  ASN A HB2  1 
ATOM   4374  H HB3  . ASN A 1 335 ? 8.301   0.992   45.736 1.00 38.00 ?  301  ASN A HB3  1 
ATOM   4375  H HD21 . ASN A 1 335 ? 10.085  3.142   44.070 1.00 59.87 ?  301  ASN A HD21 1 
ATOM   4376  H HD22 . ASN A 1 335 ? 10.290  2.403   42.794 1.00 59.87 ?  301  ASN A HD22 1 
ATOM   4377  N N    . ASP A 1 336 ? 5.536   3.453   46.858 1.00 22.70 ?  302  ASP A N    1 
ATOM   4378  C CA   . ASP A 1 336 ? 4.861   3.552   48.141 1.00 22.85 ?  302  ASP A CA   1 
ATOM   4379  C C    . ASP A 1 336 ? 3.804   2.459   48.281 1.00 31.48 ?  302  ASP A C    1 
ATOM   4380  O O    . ASP A 1 336 ? 3.049   2.171   47.353 1.00 22.86 ?  302  ASP A O    1 
ATOM   4381  C CB   . ASP A 1 336 ? 4.195   4.922   48.236 1.00 21.92 ?  302  ASP A CB   1 
ATOM   4382  C CG   . ASP A 1 336 ? 3.418   5.100   49.495 1.00 28.60 ?  302  ASP A CG   1 
ATOM   4383  O OD1  . ASP A 1 336 ? 4.064   5.376   50.547 1.00 30.69 ?  302  ASP A OD1  1 
ATOM   4384  O OD2  . ASP A 1 336 ? 2.170   5.024   49.459 1.00 29.81 ?  302  ASP A OD2  1 
ATOM   4385  H H    . ASP A 1 336 ? 5.493   4.172   46.388 1.00 27.24 ?  302  ASP A H    1 
ATOM   4386  H HA   . ASP A 1 336 ? 5.501   3.446   48.862 1.00 27.41 ?  302  ASP A HA   1 
ATOM   4387  H HB2  . ASP A 1 336 ? 4.879   5.609   48.207 1.00 26.31 ?  302  ASP A HB2  1 
ATOM   4388  H HB3  . ASP A 1 336 ? 3.584   5.029   47.490 1.00 26.31 ?  302  ASP A HB3  1 
ATOM   4389  N N    . GLU A 1 337 ? 3.724   1.855   49.467 1.00 23.67 ?  303  GLU A N    1 
ATOM   4390  C CA   . GLU A 1 337 ? 2.833   0.707   49.648 1.00 24.55 ?  303  GLU A CA   1 
ATOM   4391  C C    . GLU A 1 337 ? 1.370   1.101   49.532 1.00 24.60 ?  303  GLU A C    1 
ATOM   4392  O O    . GLU A 1 337 ? 0.582   0.411   48.867 1.00 25.25 ?  303  GLU A O    1 
ATOM   4393  C CB   . GLU A 1 337 ? 3.142   0.054   51.007 1.00 31.60 ?  303  GLU A CB   1 
ATOM   4394  C CG   . GLU A 1 337 ? 2.227   -1.094  51.405 1.00 46.17 ?  303  GLU A CG   1 
ATOM   4395  C CD   . GLU A 1 337 ? 2.377   -1.462  52.870 1.00 58.32 ?  303  GLU A CD   1 
ATOM   4396  O OE1  . GLU A 1 337 ? 1.995   -0.644  53.740 1.00 55.07 ?  303  GLU A OE1  1 
ATOM   4397  O OE2  . GLU A 1 337 ? 2.900   -2.562  53.144 1.00 56.84 ?  303  GLU A OE2  1 
ATOM   4398  H H    . GLU A 1 337 ? 4.165   2.084   50.169 1.00 28.40 ?  303  GLU A H    1 
ATOM   4399  H HA   . GLU A 1 337 ? 2.994   0.054   48.949 1.00 29.46 ?  303  GLU A HA   1 
ATOM   4400  H HB2  . GLU A 1 337 ? 4.047   -0.295  50.980 1.00 37.92 ?  303  GLU A HB2  1 
ATOM   4401  H HB3  . GLU A 1 337 ? 3.069   0.733   51.696 1.00 37.92 ?  303  GLU A HB3  1 
ATOM   4402  H HG2  . GLU A 1 337 ? 1.305   -0.835  51.251 1.00 55.41 ?  303  GLU A HG2  1 
ATOM   4403  H HG3  . GLU A 1 337 ? 2.445   -1.875  50.872 1.00 55.41 ?  303  GLU A HG3  1 
ATOM   4404  N N    . GLU A 1 338 ? 0.974   2.207   50.144 1.00 25.82 ?  304  GLU A N    1 
ATOM   4405  C CA   . GLU A 1 338 ? -0.415  2.637   50.055 1.00 26.07 ?  304  GLU A CA   1 
ATOM   4406  C C    . GLU A 1 338 ? -0.783  3.051   48.631 1.00 25.76 ?  304  GLU A C    1 
ATOM   4407  O O    . GLU A 1 338 ? -1.886  2.762   48.162 1.00 23.22 ?  304  GLU A O    1 
ATOM   4408  C CB   . GLU A 1 338 ? -0.664  3.792   51.028 1.00 32.47 ?  304  GLU A CB   1 
ATOM   4409  C CG   . GLU A 1 338 ? -0.788  3.380   52.500 1.00 49.89 ?  304  GLU A CG   1 
ATOM   4410  C CD   . GLU A 1 338 ? -1.816  2.276   52.751 1.00 45.43 ?  304  GLU A CD   1 
ATOM   4411  O OE1  . GLU A 1 338 ? -3.028  2.528   52.571 1.00 53.95 ?  304  GLU A OE1  1 
ATOM   4412  O OE2  . GLU A 1 338 ? -1.412  1.163   53.141 1.00 51.30 ?  304  GLU A OE2  1 
ATOM   4413  H H    . GLU A 1 338 ? 1.481   2.721   50.611 1.00 30.99 ?  304  GLU A H    1 
ATOM   4414  H HA   . GLU A 1 338 ? -0.987  1.896   50.308 1.00 31.29 ?  304  GLU A HA   1 
ATOM   4415  H HB2  . GLU A 1 338 ? 0.075   4.416   50.961 1.00 38.96 ?  304  GLU A HB2  1 
ATOM   4416  H HB3  . GLU A 1 338 ? -1.492  4.231   50.778 1.00 38.96 ?  304  GLU A HB3  1 
ATOM   4417  H HG2  . GLU A 1 338 ? 0.074   3.056   52.806 1.00 59.87 ?  304  GLU A HG2  1 
ATOM   4418  H HG3  . GLU A 1 338 ? -1.054  4.155   53.019 1.00 59.87 ?  304  GLU A HG3  1 
ATOM   4419  N N    . LEU A 1 339 ? 0.119   3.731   47.927 1.00 23.87 ?  305  LEU A N    1 
ATOM   4420  C CA   . LEU A 1 339 ? -0.179  4.089   46.545 1.00 21.01 ?  305  LEU A CA   1 
ATOM   4421  C C    . LEU A 1 339 ? -0.386  2.828   45.720 1.00 21.83 ?  305  LEU A C    1 
ATOM   4422  O O    . LEU A 1 339 ? -1.295  2.772   44.875 1.00 21.14 ?  305  LEU A O    1 
ATOM   4423  C CB   . LEU A 1 339 ? 0.954   4.922   45.943 1.00 23.85 ?  305  LEU A CB   1 
ATOM   4424  C CG   . LEU A 1 339 ? 0.826   5.277   44.450 1.00 21.53 ?  305  LEU A CG   1 
ATOM   4425  C CD1  . LEU A 1 339 ? -0.474  6.032   44.161 1.00 23.72 ?  305  LEU A CD1  1 
ATOM   4426  C CD2  . LEU A 1 339 ? 2.044   6.039   43.946 1.00 23.12 ?  305  LEU A CD2  1 
ATOM   4427  H H    . LEU A 1 339 ? 0.887   3.988   48.217 1.00 28.64 ?  305  LEU A H    1 
ATOM   4428  H HA   . LEU A 1 339 ? -0.983  4.632   46.526 1.00 25.21 ?  305  LEU A HA   1 
ATOM   4429  H HB2  . LEU A 1 339 ? 1.005   5.759   46.431 1.00 28.61 ?  305  LEU A HB2  1 
ATOM   4430  H HB3  . LEU A 1 339 ? 1.781   4.426   46.048 1.00 28.61 ?  305  LEU A HB3  1 
ATOM   4431  H HG   . LEU A 1 339 ? 0.788   4.448   43.949 1.00 25.84 ?  305  LEU A HG   1 
ATOM   4432  H HD11 . LEU A 1 339 ? -0.476  6.314   43.233 1.00 28.46 ?  305  LEU A HD11 1 
ATOM   4433  H HD12 . LEU A 1 339 ? -1.226  5.443   44.329 1.00 28.46 ?  305  LEU A HD12 1 
ATOM   4434  H HD13 . LEU A 1 339 ? -0.526  6.807   44.743 1.00 28.46 ?  305  LEU A HD13 1 
ATOM   4435  H HD21 . LEU A 1 339 ? 1.891   6.306   43.027 1.00 27.74 ?  305  LEU A HD21 1 
ATOM   4436  H HD22 . LEU A 1 339 ? 2.178   6.823   44.501 1.00 27.74 ?  305  LEU A HD22 1 
ATOM   4437  H HD23 . LEU A 1 339 ? 2.822   5.461   43.998 1.00 27.74 ?  305  LEU A HD23 1 
ATOM   4438  N N    . ASN A 1 340 ? 0.424   1.802   45.973 1.00 19.93 ?  306  ASN A N    1 
ATOM   4439  C CA   . ASN A 1 340 ? 0.323   0.584   45.176 1.00 20.76 ?  306  ASN A CA   1 
ATOM   4440  C C    . ASN A 1 340 ? -0.937  -0.195  45.500 1.00 21.12 ?  306  ASN A C    1 
ATOM   4441  O O    . ASN A 1 340 ? -1.452  -0.898  44.624 1.00 18.65 ?  306  ASN A O    1 
ATOM   4442  C CB   . ASN A 1 340 ? 1.596   -0.235  45.275 1.00 19.22 ?  306  ASN A CB   1 
ATOM   4443  C CG   . ASN A 1 340 ? 2.607   0.217   44.275 1.00 25.33 ?  306  ASN A CG   1 
ATOM   4444  O OD1  . ASN A 1 340 ? 2.706   -0.333  43.184 1.00 24.13 ?  306  ASN A OD1  1 
ATOM   4445  N ND2  . ASN A 1 340 ? 3.330   1.301   44.603 1.00 23.27 ?  306  ASN A ND2  1 
ATOM   4446  H H    . ASN A 1 340 ? 1.026   1.787   46.586 1.00 23.92 ?  306  ASN A H    1 
ATOM   4447  H HA   . ASN A 1 340 ? 0.252   0.815   44.237 1.00 24.91 ?  306  ASN A HA   1 
ATOM   4448  H HB2  . ASN A 1 340 ? 1.975   -0.134  46.162 1.00 23.06 ?  306  ASN A HB2  1 
ATOM   4449  H HB3  . ASN A 1 340 ? 1.392   -1.168  45.106 1.00 23.06 ?  306  ASN A HB3  1 
ATOM   4450  H HD21 . ASN A 1 340 ? 3.926   1.601   44.061 1.00 27.93 ?  306  ASN A HD21 1 
ATOM   4451  H HD22 . ASN A 1 340 ? 3.196   1.694   45.356 1.00 27.93 ?  306  ASN A HD22 1 
ATOM   4452  N N    . LYS A 1 341 ? -1.469  -0.086  46.713 1.00 21.53 ?  307  LYS A N    1 
ATOM   4453  C CA   . LYS A 1 341 ? -2.796  -0.639  46.990 1.00 22.36 ?  307  LYS A CA   1 
ATOM   4454  C C    . LYS A 1 341 ? -3.868  0.066   46.159 1.00 21.47 ?  307  LYS A C    1 
ATOM   4455  O O    . LYS A 1 341 ? -4.841  -0.561  45.708 1.00 19.36 ?  307  LYS A O    1 
ATOM   4456  C CB   . LYS A 1 341 ? -3.150  -0.523  48.481 1.00 23.60 ?  307  LYS A CB   1 
ATOM   4457  C CG   . LYS A 1 341 ? -2.222  -1.300  49.387 1.00 33.55 ?  307  LYS A CG   1 
ATOM   4458  C CD   . LYS A 1 341 ? -2.800  -1.438  50.789 1.00 40.04 ?  307  LYS A CD   1 
ATOM   4459  C CE   . LYS A 1 341 ? -1.869  -2.255  51.673 1.00 46.60 ?  307  LYS A CE   1 
ATOM   4460  N NZ   . LYS A 1 341 ? -1.465  -1.504  52.898 1.00 58.86 ?  307  LYS A NZ   1 
ATOM   4461  H H    . LYS A 1 341 ? -1.092  0.297   47.384 1.00 25.83 ?  307  LYS A H    1 
ATOM   4462  H HA   . LYS A 1 341 ? -2.775  -1.581  46.759 1.00 26.83 ?  307  LYS A HA   1 
ATOM   4463  H HB2  . LYS A 1 341 ? -3.106  0.411   48.741 1.00 28.32 ?  307  LYS A HB2  1 
ATOM   4464  H HB3  . LYS A 1 341 ? -4.049  -0.862  48.616 1.00 28.32 ?  307  LYS A HB3  1 
ATOM   4465  H HG2  . LYS A 1 341 ? -2.087  -2.189  49.023 1.00 40.26 ?  307  LYS A HG2  1 
ATOM   4466  H HG3  . LYS A 1 341 ? -1.373  -0.835  49.451 1.00 40.26 ?  307  LYS A HG3  1 
ATOM   4467  H HD2  . LYS A 1 341 ? -2.908  -0.558  51.184 1.00 48.05 ?  307  LYS A HD2  1 
ATOM   4468  H HD3  . LYS A 1 341 ? -3.658  -1.889  50.744 1.00 48.05 ?  307  LYS A HD3  1 
ATOM   4469  H HE2  . LYS A 1 341 ? -2.322  -3.067  51.950 1.00 55.92 ?  307  LYS A HE2  1 
ATOM   4470  H HE3  . LYS A 1 341 ? -1.067  -2.476  51.174 1.00 55.92 ?  307  LYS A HE3  1 
ATOM   4471  H HZ1  . LYS A 1 341 ? -0.924  -2.005  53.397 1.00 70.63 ?  307  LYS A HZ1  1 
ATOM   4472  H HZ2  . LYS A 1 341 ? -1.038  -0.757  52.670 1.00 70.63 ?  307  LYS A HZ2  1 
ATOM   4473  H HZ3  . LYS A 1 341 ? -2.185  -1.291  53.376 1.00 70.63 ?  307  LYS A HZ3  1 
ATOM   4474  N N    . ARG A 1 342 ? -3.715  1.375   45.937 1.00 19.95 ?  308  ARG A N    1 
ATOM   4475  C CA   . ARG A 1 342 ? -4.669  2.105   45.105 1.00 20.89 ?  308  ARG A CA   1 
ATOM   4476  C C    . ARG A 1 342 ? -4.540  1.685   43.644 1.00 18.20 ?  308  ARG A C    1 
ATOM   4477  O O    . ARG A 1 342 ? -5.548  1.511   42.951 1.00 17.36 ?  308  ARG A O    1 
ATOM   4478  C CB   . ARG A 1 342 ? -4.429  3.608   45.228 1.00 20.09 ?  308  ARG A CB   1 
ATOM   4479  C CG   . ARG A 1 342 ? -5.457  4.501   44.530 1.00 25.70 ?  308  ARG A CG   1 
ATOM   4480  C CD   . ARG A 1 342 ? -6.883  4.194   44.922 1.00 30.71 ?  308  ARG A CD   1 
ATOM   4481  N NE   . ARG A 1 342 ? -7.842  5.085   44.272 1.00 36.19 ?  308  ARG A NE   1 
ATOM   4482  C CZ   . ARG A 1 342 ? -9.146  5.089   44.520 1.00 23.54 ?  308  ARG A CZ   1 
ATOM   4483  N NH1  . ARG A 1 342 ? -9.676  4.298   45.438 1.00 33.29 ?  308  ARG A NH1  1 
ATOM   4484  N NH2  . ARG A 1 342 ? -9.927  5.929   43.862 1.00 35.24 ?  308  ARG A NH2  1 
ATOM   4485  H H    . ARG A 1 342 ? -3.076  1.856   46.253 1.00 23.94 ?  308  ARG A H    1 
ATOM   4486  H HA   . ARG A 1 342 ? -5.568  1.910   45.413 1.00 25.07 ?  308  ARG A HA   1 
ATOM   4487  H HB2  . ARG A 1 342 ? -4.437  3.842   46.170 1.00 24.10 ?  308  ARG A HB2  1 
ATOM   4488  H HB3  . ARG A 1 342 ? -3.562  3.811   44.844 1.00 24.10 ?  308  ARG A HB3  1 
ATOM   4489  H HG2  . ARG A 1 342 ? -5.278  5.426   44.760 1.00 30.84 ?  308  ARG A HG2  1 
ATOM   4490  H HG3  . ARG A 1 342 ? -5.380  4.377   43.571 1.00 30.84 ?  308  ARG A HG3  1 
ATOM   4491  H HD2  . ARG A 1 342 ? -7.096  3.284   44.665 1.00 36.85 ?  308  ARG A HD2  1 
ATOM   4492  H HD3  . ARG A 1 342 ? -6.978  4.298   45.882 1.00 36.85 ?  308  ARG A HD3  1 
ATOM   4493  H HE   . ARG A 1 342 ? -7.541  5.644   43.690 1.00 43.42 ?  308  ARG A HE   1 
ATOM   4494  H HH11 . ARG A 1 342 ? -9.173  3.766   45.889 1.00 39.95 ?  308  ARG A HH11 1 
ATOM   4495  H HH12 . ARG A 1 342 ? -10.523 4.316   45.584 1.00 39.95 ?  308  ARG A HH12 1 
ATOM   4496  H HH21 . ARG A 1 342 ? -9.589  6.465   43.280 1.00 42.28 ?  308  ARG A HH21 1 
ATOM   4497  H HH22 . ARG A 1 342 ? -10.773 5.939   44.015 1.00 42.28 ?  308  ARG A HH22 1 
ATOM   4498  N N    . VAL A 1 343 ? -3.320  1.497   43.181 1.00 16.40 ?  309  VAL A N    1 
ATOM   4499  C CA   . VAL A 1 343 ? -3.095  0.994   41.828 1.00 15.55 ?  309  VAL A CA   1 
ATOM   4500  C C    . VAL A 1 343 ? -3.751  -0.362  41.669 1.00 17.53 ?  309  VAL A C    1 
ATOM   4501  O O    . VAL A 1 343 ? -4.463  -0.616  40.687 1.00 16.64 ?  309  VAL A O    1 
ATOM   4502  C CB   . VAL A 1 343 ? -1.601  0.953   41.521 1.00 14.70 ?  309  VAL A CB   1 
ATOM   4503  C CG1  . VAL A 1 343 ? -1.303  0.195   40.258 1.00 17.23 ?  309  VAL A CG1  1 
ATOM   4504  C CG2  . VAL A 1 343 ? -1.014  2.390   41.422 1.00 17.23 ?  309  VAL A CG2  1 
ATOM   4505  H H    . VAL A 1 343 ? -2.599  1.650   43.625 1.00 19.68 ?  309  VAL A H    1 
ATOM   4506  H HA   . VAL A 1 343 ? -3.505  1.598   41.190 1.00 18.66 ?  309  VAL A HA   1 
ATOM   4507  H HB   . VAL A 1 343 ? -1.172  0.486   42.255 1.00 17.64 ?  309  VAL A HB   1 
ATOM   4508  H HG11 . VAL A 1 343 ? -0.376  0.340   40.014 1.00 20.67 ?  309  VAL A HG11 1 
ATOM   4509  H HG12 . VAL A 1 343 ? -1.460  -0.750  40.413 1.00 20.67 ?  309  VAL A HG12 1 
ATOM   4510  H HG13 . VAL A 1 343 ? -1.885  0.516   39.552 1.00 20.67 ?  309  VAL A HG13 1 
ATOM   4511  H HG21 . VAL A 1 343 ? -0.060  2.331   41.258 1.00 20.67 ?  309  VAL A HG21 1 
ATOM   4512  H HG22 . VAL A 1 343 ? -1.446  2.858   40.690 1.00 20.67 ?  309  VAL A HG22 1 
ATOM   4513  H HG23 . VAL A 1 343 ? -1.178  2.856   42.256 1.00 20.67 ?  309  VAL A HG23 1 
ATOM   4514  N N    . ASP A 1 344 ? -3.551  -1.258  42.647 1.00 15.98 ?  310  ASP A N    1 
ATOM   4515  C CA   . ASP A 1 344 ? -4.189  -2.580  42.591 1.00 16.04 ?  310  ASP A CA   1 
ATOM   4516  C C    . ASP A 1 344 ? -5.700  -2.451  42.469 1.00 16.59 ?  310  ASP A C    1 
ATOM   4517  O O    . ASP A 1 344 ? -6.342  -3.172  41.684 1.00 17.16 ?  310  ASP A O    1 
ATOM   4518  C CB   . ASP A 1 344 ? -3.874  -3.382  43.862 1.00 16.98 ?  310  ASP A CB   1 
ATOM   4519  C CG   . ASP A 1 344 ? -2.470  -3.866  43.906 1.00 17.81 ?  310  ASP A CG   1 
ATOM   4520  O OD1  . ASP A 1 344 ? -1.718  -3.855  42.915 1.00 17.14 ?  310  ASP A OD1  1 
ATOM   4521  O OD2  . ASP A 1 344 ? -2.050  -4.312  45.009 1.00 21.12 ?  310  ASP A OD2  1 
ATOM   4522  H H    . ASP A 1 344 ? -3.059  -1.128  43.340 1.00 19.17 ?  310  ASP A H    1 
ATOM   4523  H HA   . ASP A 1 344 ? -3.834  -3.048  41.819 1.00 19.25 ?  310  ASP A HA   1 
ATOM   4524  H HB2  . ASP A 1 344 ? -4.020  -2.817  44.636 1.00 20.38 ?  310  ASP A HB2  1 
ATOM   4525  H HB3  . ASP A 1 344 ? -4.459  -4.155  43.900 1.00 20.38 ?  310  ASP A HB3  1 
ATOM   4526  N N    . TYR A 1 345 ? -6.310  -1.578  43.267 1.00 17.08 ?  311  TYR A N    1 
ATOM   4527  C CA   . TYR A 1 345 ? -7.746  -1.381  43.262 1.00 15.98 ?  311  TYR A CA   1 
ATOM   4528  C C    . TYR A 1 345 ? -8.240  -0.896  41.901 1.00 17.08 ?  311  TYR A C    1 
ATOM   4529  O O    . TYR A 1 345 ? -9.197  -1.444  41.331 1.00 16.01 ?  311  TYR A O    1 
ATOM   4530  C CB   . TYR A 1 345 ? -8.150  -0.396  44.375 1.00 17.56 ?  311  TYR A CB   1 
ATOM   4531  C CG   . TYR A 1 345 ? -9.609  -0.024  44.375 1.00 17.17 ?  311  TYR A CG   1 
ATOM   4532  C CD1  . TYR A 1 345 ? -10.579 -0.967  44.676 1.00 20.46 ?  311  TYR A CD1  1 
ATOM   4533  C CD2  . TYR A 1 345 ? -10.030 1.262   44.057 1.00 17.77 ?  311  TYR A CD2  1 
ATOM   4534  C CE1  . TYR A 1 345 ? -11.895 -0.650  44.683 1.00 20.03 ?  311  TYR A CE1  1 
ATOM   4535  C CE2  . TYR A 1 345 ? -11.366 1.587   44.071 1.00 20.29 ?  311  TYR A CE2  1 
ATOM   4536  C CZ   . TYR A 1 345 ? -12.304 0.625   44.383 1.00 18.73 ?  311  TYR A CZ   1 
ATOM   4537  O OH   . TYR A 1 345 ? -13.656 0.887   44.408 1.00 25.78 ?  311  TYR A OH   1 
ATOM   4538  H H    . TYR A 1 345 ? -5.901  -1.077  43.834 1.00 20.49 ?  311  TYR A H    1 
ATOM   4539  H HA   . TYR A 1 345 ? -8.174  -2.233  43.445 1.00 19.17 ?  311  TYR A HA   1 
ATOM   4540  H HB2  . TYR A 1 345 ? -7.950  -0.800  45.234 1.00 21.07 ?  311  TYR A HB2  1 
ATOM   4541  H HB3  . TYR A 1 345 ? -7.639  0.421   44.266 1.00 21.07 ?  311  TYR A HB3  1 
ATOM   4542  H HD1  . TYR A 1 345 ? -10.320 -1.837  44.877 1.00 24.55 ?  311  TYR A HD1  1 
ATOM   4543  H HD2  . TYR A 1 345 ? -9.402  1.910   43.832 1.00 21.33 ?  311  TYR A HD2  1 
ATOM   4544  H HE1  . TYR A 1 345 ? -12.525 -1.300  44.892 1.00 24.04 ?  311  TYR A HE1  1 
ATOM   4545  H HE2  . TYR A 1 345 ? -11.637 2.454   43.871 1.00 24.35 ?  311  TYR A HE2  1 
ATOM   4546  H HH   . TYR A 1 345 ? -13.796 1.693   44.214 1.00 30.94 ?  311  TYR A HH   1 
ATOM   4547  N N    . LEU A 1 346 ? -7.610  0.147   41.362 1.00 15.13 ?  312  LEU A N    1 
ATOM   4548  C CA   . LEU A 1 346 ? -8.068  0.670   40.077 1.00 16.71 ?  312  LEU A CA   1 
ATOM   4549  C C    . LEU A 1 346 ? -7.843  -0.343  38.951 1.00 13.95 ?  312  LEU A C    1 
ATOM   4550  O O    . LEU A 1 346 ? -8.696  -0.488  38.066 1.00 14.45 ?  312  LEU A O    1 
ATOM   4551  C CB   . LEU A 1 346 ? -7.354  1.988   39.784 1.00 16.38 ?  312  LEU A CB   1 
ATOM   4552  C CG   . LEU A 1 346 ? -7.610  3.102   40.823 1.00 14.83 ?  312  LEU A CG   1 
ATOM   4553  C CD1  . LEU A 1 346 ? -6.778  4.358   40.518 1.00 18.03 ?  312  LEU A CD1  1 
ATOM   4554  C CD2  . LEU A 1 346 ? -9.070  3.440   40.893 1.00 17.12 ?  312  LEU A CD2  1 
ATOM   4555  H H    . LEU A 1 346 ? -6.937  0.557   41.707 1.00 18.16 ?  312  LEU A H    1 
ATOM   4556  H HA   . LEU A 1 346 ? -9.021  0.846   40.123 1.00 20.05 ?  312  LEU A HA   1 
ATOM   4557  H HB2  . LEU A 1 346 ? -6.399  1.822   39.760 1.00 19.66 ?  312  LEU A HB2  1 
ATOM   4558  H HB3  . LEU A 1 346 ? -7.655  2.316   38.922 1.00 19.66 ?  312  LEU A HB3  1 
ATOM   4559  H HG   . LEU A 1 346 ? -7.333  2.774   41.693 1.00 17.80 ?  312  LEU A HG   1 
ATOM   4560  H HD11 . LEU A 1 346 ? -6.965  5.032   41.190 1.00 21.64 ?  312  LEU A HD11 1 
ATOM   4561  H HD12 . LEU A 1 346 ? -5.836  4.125   40.536 1.00 21.64 ?  312  LEU A HD12 1 
ATOM   4562  H HD13 . LEU A 1 346 ? -7.019  4.691   39.639 1.00 21.64 ?  312  LEU A HD13 1 
ATOM   4563  H HD21 . LEU A 1 346 ? -9.180  4.261   41.398 1.00 20.55 ?  312  LEU A HD21 1 
ATOM   4564  H HD22 . LEU A 1 346 ? -9.410  3.558   39.992 1.00 20.55 ?  312  LEU A HD22 1 
ATOM   4565  H HD23 . LEU A 1 346 ? -9.541  2.715   41.332 1.00 20.55 ?  312  LEU A HD23 1 
ATOM   4566  N N    . LEU A 1 347 ? -6.736  -1.043  38.973 1.00 14.84 ?  313  LEU A N    1 
ATOM   4567  C CA   . LEU A 1 347 ? -6.511  -2.072  37.972 1.00 13.01 ?  313  LEU A CA   1 
ATOM   4568  C C    . LEU A 1 347 ? -7.512  -3.190  38.128 1.00 16.74 ?  313  LEU A C    1 
ATOM   4569  O O    . LEU A 1 347 ? -7.927  -3.774  37.130 1.00 14.72 ?  313  LEU A O    1 
ATOM   4570  C CB   . LEU A 1 347 ? -5.111  -2.655  38.037 1.00 15.11 ?  313  LEU A CB   1 
ATOM   4571  C CG   . LEU A 1 347 ? -3.981  -1.716  37.614 1.00 15.50 ?  313  LEU A CG   1 
ATOM   4572  C CD1  . LEU A 1 347 ? -2.622  -2.369  37.783 1.00 16.01 ?  313  LEU A CD1  1 
ATOM   4573  C CD2  . LEU A 1 347 ? -4.195  -1.242  36.154 1.00 17.34 ?  313  LEU A CD2  1 
ATOM   4574  H H    . LEU A 1 347 ? -6.101  -0.949  39.546 1.00 17.80 ?  313  LEU A H    1 
ATOM   4575  H HA   . LEU A 1 347 ? -6.605  -1.647  37.105 1.00 15.61 ?  313  LEU A HA   1 
ATOM   4576  H HB2  . LEU A 1 347 ? -4.936  -2.923  38.953 1.00 18.14 ?  313  LEU A HB2  1 
ATOM   4577  H HB3  . LEU A 1 347 ? -5.077  -3.428  37.453 1.00 18.14 ?  313  LEU A HB3  1 
ATOM   4578  H HG   . LEU A 1 347 ? -3.993  -0.937  38.191 1.00 18.60 ?  313  LEU A HG   1 
ATOM   4579  H HD11 . LEU A 1 347 ? -1.937  -1.757  37.472 1.00 19.22 ?  313  LEU A HD11 1 
ATOM   4580  H HD12 . LEU A 1 347 ? -2.483  -2.572  38.722 1.00 19.22 ?  313  LEU A HD12 1 
ATOM   4581  H HD13 . LEU A 1 347 ? -2.597  -3.187  37.261 1.00 19.22 ?  313  LEU A HD13 1 
ATOM   4582  H HD21 . LEU A 1 347 ? -3.434  -0.707  35.881 1.00 20.81 ?  313  LEU A HD21 1 
ATOM   4583  H HD22 . LEU A 1 347 ? -4.277  -2.019  35.579 1.00 20.81 ?  313  LEU A HD22 1 
ATOM   4584  H HD23 . LEU A 1 347 ? -5.006  -0.711  36.110 1.00 20.81 ?  313  LEU A HD23 1 
ATOM   4585  N N    . ALA A 1 348 ? -7.906  -3.524  39.361 1.00 15.84 ?  314  ALA A N    1 
ATOM   4586  C CA   . ALA A 1 348 ? -8.896  -4.566  39.546 1.00 15.66 ?  314  ALA A CA   1 
ATOM   4587  C C    . ALA A 1 348 ? -10.231 -4.188  38.931 1.00 14.35 ?  314  ALA A C    1 
ATOM   4588  O O    . ALA A 1 348 ? -10.884 -5.013  38.282 1.00 14.59 ?  314  ALA A O    1 
ATOM   4589  C CB   . ALA A 1 348 ? -9.075  -4.906  41.033 1.00 16.01 ?  314  ALA A CB   1 
ATOM   4590  H H    . ALA A 1 348 ? -7.617  -3.165  40.087 1.00 19.01 ?  314  ALA A H    1 
ATOM   4591  H HA   . ALA A 1 348 ? -8.569  -5.363  39.100 1.00 18.80 ?  314  ALA A HA   1 
ATOM   4592  H HB1  . ALA A 1 348 ? -9.749  -5.598  41.120 1.00 19.22 ?  314  ALA A HB1  1 
ATOM   4593  H HB2  . ALA A 1 348 ? -8.229  -5.222  41.388 1.00 19.22 ?  314  ALA A HB2  1 
ATOM   4594  H HB3  . ALA A 1 348 ? -9.357  -4.109  41.508 1.00 19.22 ?  314  ALA A HB3  1 
ATOM   4595  N N    . ILE A 1 349 ? -10.657 -2.932  39.069 1.00 14.71 ?  315  ILE A N    1 
ATOM   4596  C CA   . ILE A 1 349 ? -11.877 -2.488  38.410 1.00 13.43 ?  315  ILE A CA   1 
ATOM   4597  C C    . ILE A 1 349 ? -11.755 -2.707  36.906 1.00 14.83 ?  315  ILE A C    1 
ATOM   4598  O O    . ILE A 1 349 ? -12.662 -3.234  36.260 1.00 14.33 ?  315  ILE A O    1 
ATOM   4599  C CB   . ILE A 1 349 ? -12.137 -0.999  38.713 1.00 14.31 ?  315  ILE A CB   1 
ATOM   4600  C CG1  . ILE A 1 349 ? -12.459 -0.786  40.195 1.00 18.24 ?  315  ILE A CG1  1 
ATOM   4601  C CG2  . ILE A 1 349 ? -13.284 -0.443  37.837 1.00 16.31 ?  315  ILE A CG2  1 
ATOM   4602  C CD1  . ILE A 1 349 ? -12.508 0.670   40.642 1.00 18.20 ?  315  ILE A CD1  1 
ATOM   4603  H H    . ILE A 1 349 ? -10.260 -2.327  39.534 1.00 17.65 ?  315  ILE A H    1 
ATOM   4604  H HA   . ILE A 1 349 ? -12.621 -3.010  38.750 1.00 16.11 ?  315  ILE A HA   1 
ATOM   4605  H HB   . ILE A 1 349 ? -11.323 -0.517  38.501 1.00 17.17 ?  315  ILE A HB   1 
ATOM   4606  H HG12 . ILE A 1 349 ? -13.328 -1.176  40.380 1.00 21.89 ?  315  ILE A HG12 1 
ATOM   4607  H HG13 . ILE A 1 349 ? -11.777 -1.229  40.724 1.00 21.89 ?  315  ILE A HG13 1 
ATOM   4608  H HG21 . ILE A 1 349 ? -13.524 0.442   38.155 1.00 19.57 ?  315  ILE A HG21 1 
ATOM   4609  H HG22 . ILE A 1 349 ? -12.983 -0.393  36.917 1.00 19.57 ?  315  ILE A HG22 1 
ATOM   4610  H HG23 . ILE A 1 349 ? -14.048 -1.036  37.904 1.00 19.57 ?  315  ILE A HG23 1 
ATOM   4611  H HD11 . ILE A 1 349 ? -12.613 0.701   41.606 1.00 21.83 ?  315  ILE A HD11 1 
ATOM   4612  H HD12 . ILE A 1 349 ? -11.682 1.108   40.384 1.00 21.83 ?  315  ILE A HD12 1 
ATOM   4613  H HD13 . ILE A 1 349 ? -13.261 1.106   40.214 1.00 21.83 ?  315  ILE A HD13 1 
ATOM   4614  N N    . PHE A 1 350 ? -10.629 -2.284  36.333 1.00 13.40 ?  316  PHE A N    1 
ATOM   4615  C CA   . PHE A 1 350 ? -10.388 -2.454  34.902 1.00 13.94 ?  316  PHE A CA   1 
ATOM   4616  C C    . PHE A 1 350 ? -10.429 -3.927  34.510 1.00 13.27 ?  316  PHE A C    1 
ATOM   4617  O O    . PHE A 1 350 ? -11.137 -4.297  33.560 1.00 12.98 ?  316  PHE A O    1 
ATOM   4618  C CB   . PHE A 1 350 ? -9.042  -1.852  34.522 1.00 12.86 ?  316  PHE A CB   1 
ATOM   4619  C CG   . PHE A 1 350 ? -8.614  -2.187  33.119 1.00 12.38 ?  316  PHE A CG   1 
ATOM   4620  C CD1  . PHE A 1 350 ? -9.281  -1.667  32.018 1.00 11.94 ?  316  PHE A CD1  1 
ATOM   4621  C CD2  . PHE A 1 350 ? -7.561  -3.058  32.910 1.00 13.48 ?  316  PHE A CD2  1 
ATOM   4622  C CE1  . PHE A 1 350 ? -8.892  -2.025  30.747 1.00 12.72 ?  316  PHE A CE1  1 
ATOM   4623  C CE2  . PHE A 1 350 ? -7.160  -3.373  31.620 1.00 14.06 ?  316  PHE A CE2  1 
ATOM   4624  C CZ   . PHE A 1 350 ? -7.849  -2.888  30.539 1.00 12.49 ?  316  PHE A CZ   1 
ATOM   4625  H H    . PHE A 1 350 ? -9.986  -1.896  36.752 1.00 16.08 ?  316  PHE A H    1 
ATOM   4626  H HA   . PHE A 1 350 ? -11.083 -1.984  34.415 1.00 16.73 ?  316  PHE A HA   1 
ATOM   4627  H HB2  . PHE A 1 350 ? -9.100  -0.886  34.593 1.00 15.44 ?  316  PHE A HB2  1 
ATOM   4628  H HB3  . PHE A 1 350 ? -8.365  -2.189  35.129 1.00 15.44 ?  316  PHE A HB3  1 
ATOM   4629  H HD1  . PHE A 1 350 ? -9.989  -1.076  32.139 1.00 14.32 ?  316  PHE A HD1  1 
ATOM   4630  H HD2  . PHE A 1 350 ? -7.120  -3.435  33.637 1.00 16.18 ?  316  PHE A HD2  1 
ATOM   4631  H HE1  . PHE A 1 350 ? -9.347  -1.675  30.015 1.00 15.26 ?  316  PHE A HE1  1 
ATOM   4632  H HE2  . PHE A 1 350 ? -6.418  -3.917  31.487 1.00 16.87 ?  316  PHE A HE2  1 
ATOM   4633  H HZ   . PHE A 1 350 ? -7.611  -3.141  29.677 1.00 14.98 ?  316  PHE A HZ   1 
ATOM   4634  N N    . LEU A 1 351 ? -9.734  -4.788  35.265 1.00 13.63 ?  317  LEU A N    1 
ATOM   4635  C CA   . LEU A 1 351 ? -9.636  -6.209  34.898 1.00 12.88 ?  317  LEU A CA   1 
ATOM   4636  C C    . LEU A 1 351 ? -10.941 -6.943  35.057 1.00 14.00 ?  317  LEU A C    1 
ATOM   4637  O O    . LEU A 1 351 ? -11.151 -7.933  34.343 1.00 14.42 ?  317  LEU A O    1 
ATOM   4638  C CB   . LEU A 1 351 ? -8.500  -6.841  35.671 1.00 14.63 ?  317  LEU A CB   1 
ATOM   4639  C CG   . LEU A 1 351 ? -7.098  -6.421  35.285 1.00 14.32 ?  317  LEU A CG   1 
ATOM   4640  C CD1  . LEU A 1 351 ? -6.106  -6.876  36.361 1.00 17.32 ?  317  LEU A CD1  1 
ATOM   4641  C CD2  . LEU A 1 351 ? -6.673  -6.944  33.922 1.00 17.96 ?  317  LEU A CD2  1 
ATOM   4642  H H    . LEU A 1 351 ? -9.314  -4.579  35.986 1.00 16.36 ?  317  LEU A H    1 
ATOM   4643  H HA   . LEU A 1 351 ? -9.420  -6.289  33.956 1.00 15.45 ?  317  LEU A HA   1 
ATOM   4644  H HB2  . LEU A 1 351 ? -8.615  -6.620  36.608 1.00 17.56 ?  317  LEU A HB2  1 
ATOM   4645  H HB3  . LEU A 1 351 ? -8.552  -7.802  35.547 1.00 17.56 ?  317  LEU A HB3  1 
ATOM   4646  H HG   . LEU A 1 351 ? -7.088  -5.453  35.218 1.00 17.18 ?  317  LEU A HG   1 
ATOM   4647  H HD11 . LEU A 1 351 ? -5.217  -6.573  36.120 1.00 20.78 ?  317  LEU A HD11 1 
ATOM   4648  H HD12 . LEU A 1 351 ? -6.366  -6.493  37.213 1.00 20.78 ?  317  LEU A HD12 1 
ATOM   4649  H HD13 . LEU A 1 351 ? -6.122  -7.845  36.416 1.00 20.78 ?  317  LEU A HD13 1 
ATOM   4650  H HD21 . LEU A 1 351 ? -5.786  -6.608  33.718 1.00 21.55 ?  317  LEU A HD21 1 
ATOM   4651  H HD22 . LEU A 1 351 ? -6.662  -7.913  33.945 1.00 21.55 ?  317  LEU A HD22 1 
ATOM   4652  H HD23 . LEU A 1 351 ? -7.305  -6.636  33.254 1.00 21.55 ?  317  LEU A HD23 1 
ATOM   4653  N N    . ILE A 1 352 ? -11.812 -6.518  35.958 1.00 14.19 ?  318  ILE A N    1 
ATOM   4654  C CA   . ILE A 1 352 ? -13.140 -7.095  36.069 1.00 15.08 ?  318  ILE A CA   1 
ATOM   4655  C C    . ILE A 1 352 ? -13.948 -6.846  34.810 1.00 16.68 ?  318  ILE A C    1 
ATOM   4656  O O    . ILE A 1 352 ? -14.891 -7.593  34.515 1.00 15.55 ?  318  ILE A O    1 
ATOM   4657  C CB   . ILE A 1 352 ? -13.866 -6.561  37.318 1.00 18.45 ?  318  ILE A CB   1 
ATOM   4658  C CG1  . ILE A 1 352 ? -13.340 -7.192  38.613 1.00 21.55 ?  318  ILE A CG1  1 
ATOM   4659  C CG2  . ILE A 1 352 ? -15.385 -6.681  37.226 1.00 24.22 ?  318  ILE A CG2  1 
ATOM   4660  C CD1  . ILE A 1 352 ? -12.924 -8.610  38.535 1.00 23.80 ?  318  ILE A CD1  1 
ATOM   4661  H H    . ILE A 1 352 ? -11.657 -5.889  36.524 1.00 17.03 ?  318  ILE A H    1 
ATOM   4662  H HA   . ILE A 1 352 ? -13.050 -8.054  36.181 1.00 18.10 ?  318  ILE A HA   1 
ATOM   4663  H HB   . ILE A 1 352 ? -13.658 -5.614  37.346 1.00 22.14 ?  318  ILE A HB   1 
ATOM   4664  H HG12 . ILE A 1 352 ? -12.567 -6.685  38.904 1.00 25.86 ?  318  ILE A HG12 1 
ATOM   4665  H HG13 . ILE A 1 352 ? -14.042 -7.139  39.281 1.00 25.86 ?  318  ILE A HG13 1 
ATOM   4666  H HG21 . ILE A 1 352 ? -15.771 -6.476  38.092 1.00 29.06 ?  318  ILE A HG21 1 
ATOM   4667  H HG22 . ILE A 1 352 ? -15.712 -6.055  36.561 1.00 29.06 ?  318  ILE A HG22 1 
ATOM   4668  H HG23 . ILE A 1 352 ? -15.615 -7.587  36.967 1.00 29.06 ?  318  ILE A HG23 1 
ATOM   4669  H HD11 . ILE A 1 352 ? -12.824 -8.961  39.434 1.00 28.55 ?  318  ILE A HD11 1 
ATOM   4670  H HD12 . ILE A 1 352 ? -13.602 -9.113  38.058 1.00 28.55 ?  318  ILE A HD12 1 
ATOM   4671  H HD13 . ILE A 1 352 ? -12.078 -8.665  38.062 1.00 28.55 ?  318  ILE A HD13 1 
ATOM   4672  N N    . CYS A 1 353 ? -13.608 -5.803  34.037 1.00 15.30 ?  319  CYS A N    1 
ATOM   4673  C CA   . CYS A 1 353 ? -14.349 -5.442  32.825 1.00 13.64 ?  319  CYS A CA   1 
ATOM   4674  C C    . CYS A 1 353 ? -13.691 -5.904  31.537 1.00 13.99 ?  319  CYS A C    1 
ATOM   4675  O O    . CYS A 1 353 ? -14.402 -6.116  30.554 1.00 15.19 ?  319  CYS A O    1 
ATOM   4676  C CB   . CYS A 1 353 ? -14.442 -3.912  32.725 1.00 13.47 ?  319  CYS A CB   1 
ATOM   4677  S SG   . CYS A 1 353 ? -15.349 -3.107  34.081 1.00 15.20 ?  319  CYS A SG   1 
ATOM   4678  H H    . CYS A 1 353 ? -12.942 -5.284  34.198 1.00 18.36 ?  319  CYS A H    1 
ATOM   4679  H HA   . CYS A 1 353 ? -15.231 -5.840  32.888 1.00 16.37 ?  319  CYS A HA   1 
ATOM   4680  H HB2  . CYS A 1 353 ? -13.542 -3.549  32.722 1.00 16.17 ?  319  CYS A HB2  1 
ATOM   4681  H HB3  . CYS A 1 353 ? -14.894 -3.685  31.898 1.00 16.17 ?  319  CYS A HB3  1 
ATOM   4682  H HG   . CYS A 1 353 ? -14.751 -3.280  35.107 1.00 18.24 ?  319  CYS A HG   1 
ATOM   4683  N N    . ALA A 1 354 ? -12.380 -6.036  31.514 1.00 12.86 ?  320  ALA A N    1 
ATOM   4684  C CA   . ALA A 1 354 ? -11.608 -6.063  30.279 1.00 13.55 ?  320  ALA A CA   1 
ATOM   4685  C C    . ALA A 1 354 ? -11.953 -7.237  29.372 1.00 15.12 ?  320  ALA A C    1 
ATOM   4686  O O    . ALA A 1 354 ? -12.175 -8.363  29.819 1.00 14.52 ?  320  ALA A O    1 
ATOM   4687  C CB   . ALA A 1 354 ? -10.127 -6.111  30.604 1.00 15.01 ?  320  ALA A CB   1 
ATOM   4688  H H    . ALA A 1 354 ? -11.894 -6.116  32.219 1.00 15.43 ?  320  ALA A H    1 
ATOM   4689  H HA   . ALA A 1 354 ? -11.822 -5.256  29.785 1.00 16.27 ?  320  ALA A HA   1 
ATOM   4690  H HB1  . ALA A 1 354 ? -9.621  -6.072  29.777 1.00 18.01 ?  320  ALA A HB1  1 
ATOM   4691  H HB2  . ALA A 1 354 ? -9.902  -5.352  31.165 1.00 18.01 ?  320  ALA A HB2  1 
ATOM   4692  H HB3  . ALA A 1 354 ? -9.933  -6.938  31.072 1.00 18.01 ?  320  ALA A HB3  1 
ATOM   4693  N N    . GLU A 1 355 ? -11.883 -6.971  28.079 1.00 12.55 ?  321  GLU A N    1 
ATOM   4694  C CA   . GLU A 1 355 ? -11.836 -7.986  27.028 1.00 11.83 ?  321  GLU A CA   1 
ATOM   4695  C C    . GLU A 1 355 ? -10.747 -7.601  26.053 1.00 13.72 ?  321  GLU A C    1 
ATOM   4696  O O    . GLU A 1 355 ? -10.062 -6.588  26.223 1.00 13.65 ?  321  GLU A O    1 
ATOM   4697  C CB   . GLU A 1 355 ? -13.177 -8.141  26.323 1.00 13.83 ?  321  GLU A CB   1 
ATOM   4698  C CG   . GLU A 1 355 ? -14.324 -8.569  27.247 1.00 13.95 ?  321  GLU A CG   1 
ATOM   4699  C CD   . GLU A 1 355 ? -14.234 -10.011 27.736 1.00 17.98 ?  321  GLU A CD   1 
ATOM   4700  O OE1  . GLU A 1 355 ? -13.544 -10.806 27.056 1.00 19.82 ?  321  GLU A OE1  1 
ATOM   4701  O OE2  . GLU A 1 355 ? -14.801 -10.301 28.807 1.00 16.83 ?  321  GLU A OE2  1 
ATOM   4702  H H    . GLU A 1 355 ? -11.859 -6.171  27.765 1.00 15.06 ?  321  GLU A H    1 
ATOM   4703  H HA   . GLU A 1 355 ? -11.621 -8.845  27.422 1.00 14.19 ?  321  GLU A HA   1 
ATOM   4704  H HB2  . GLU A 1 355 ? -13.419 -7.290  25.926 1.00 16.60 ?  321  GLU A HB2  1 
ATOM   4705  H HB3  . GLU A 1 355 ? -13.088 -8.816  25.632 1.00 16.60 ?  321  GLU A HB3  1 
ATOM   4706  H HG2  . GLU A 1 355 ? -14.323 -7.994  28.028 1.00 16.74 ?  321  GLU A HG2  1 
ATOM   4707  H HG3  . GLU A 1 355 ? -15.161 -8.474  26.766 1.00 16.74 ?  321  GLU A HG3  1 
ATOM   4708  N N    . LYS A 1 356 ? -10.548 -8.389  25.012 1.00 13.48 ?  322  LYS A N    1 
ATOM   4709  C CA   . LYS A 1 356 ? -9.677  -7.995  23.936 1.00 13.13 ?  322  LYS A CA   1 
ATOM   4710  C C    . LYS A 1 356 ? -10.023 -6.570  23.500 1.00 11.88 ?  322  LYS A C    1 
ATOM   4711  O O    . LYS A 1 356 ? -11.190 -6.235  23.326 1.00 13.62 ?  322  LYS A O    1 
ATOM   4712  C CB   . LYS A 1 356 ? -9.862  -8.982  22.776 1.00 16.95 ?  322  LYS A CB   1 
ATOM   4713  C CG   . LYS A 1 356 ? -8.939  -8.775  21.650 1.00 17.24 ?  322  LYS A CG   1 
ATOM   4714  C CD   . LYS A 1 356 ? -9.015  -9.961  20.652 1.00 14.56 ?  322  LYS A CD   1 
ATOM   4715  C CE   . LYS A 1 356 ? -10.405 -10.124 20.058 1.00 16.58 ?  322  LYS A CE   1 
ATOM   4716  N NZ   . LYS A 1 356 ? -10.402 -11.063 18.865 1.00 14.02 ?  322  LYS A NZ   1 
ATOM   4717  H H    . LYS A 1 356 ? -10.910 -9.162  24.908 1.00 16.17 ?  322  LYS A H    1 
ATOM   4718  H HA   . LYS A 1 356 ? -8.747  -8.012  24.211 1.00 15.76 ?  322  LYS A HA   1 
ATOM   4719  H HB2  . LYS A 1 356 ? -9.721  -9.881  23.110 1.00 20.33 ?  322  LYS A HB2  1 
ATOM   4720  H HB3  . LYS A 1 356 ? -10.765 -8.892  22.435 1.00 20.33 ?  322  LYS A HB3  1 
ATOM   4721  H HG2  . LYS A 1 356 ? -9.178  -7.961  21.180 1.00 20.68 ?  322  LYS A HG2  1 
ATOM   4722  H HG3  . LYS A 1 356 ? -8.030  -8.711  21.984 1.00 20.68 ?  322  LYS A HG3  1 
ATOM   4723  H HD2  . LYS A 1 356 ? -8.392  -9.805  19.925 1.00 17.47 ?  322  LYS A HD2  1 
ATOM   4724  H HD3  . LYS A 1 356 ? -8.786  -10.782 21.115 1.00 17.47 ?  322  LYS A HD3  1 
ATOM   4725  H HE2  . LYS A 1 356 ? -11.000 -10.490 20.731 1.00 19.90 ?  322  LYS A HE2  1 
ATOM   4726  H HE3  . LYS A 1 356 ? -10.730 -9.259  19.763 1.00 19.90 ?  322  LYS A HE3  1 
ATOM   4727  H HZ1  . LYS A 1 356 ? -10.137 -11.874 19.116 1.00 16.83 ?  322  LYS A HZ1  1 
ATOM   4728  H HZ2  . LYS A 1 356 ? -11.221 -11.120 18.520 1.00 16.83 ?  322  LYS A HZ2  1 
ATOM   4729  H HZ3  . LYS A 1 356 ? -9.846  -10.758 18.239 1.00 16.83 ?  322  LYS A HZ3  1 
ATOM   4730  N N    . TYR A 1 357 ? -8.980  -5.741  23.333 1.00 12.27 ?  323  TYR A N    1 
ATOM   4731  C CA   . TYR A 1 357 ? -9.075  -4.319  22.925 1.00 11.36 ?  323  TYR A CA   1 
ATOM   4732  C C    . TYR A 1 357 ? -9.548  -3.409  24.048 1.00 13.08 ?  323  TYR A C    1 
ATOM   4733  O O    . TYR A 1 357 ? -10.021 -2.288  23.766 1.00 13.21 ?  323  TYR A O    1 
ATOM   4734  C CB   . TYR A 1 357 ? -9.870  -4.106  21.640 1.00 13.93 ?  323  TYR A CB   1 
ATOM   4735  C CG   . TYR A 1 357 ? -9.307  -4.934  20.501 1.00 12.94 ?  323  TYR A CG   1 
ATOM   4736  C CD1  . TYR A 1 357 ? -8.006  -4.786  20.089 1.00 14.32 ?  323  TYR A CD1  1 
ATOM   4737  C CD2  . TYR A 1 357 ? -10.093 -5.880  19.856 1.00 15.58 ?  323  TYR A CD2  1 
ATOM   4738  C CE1  . TYR A 1 357 ? -7.471  -5.522  19.043 1.00 14.65 ?  323  TYR A CE1  1 
ATOM   4739  C CE2  . TYR A 1 357 ? -9.558  -6.645  18.818 1.00 15.59 ?  323  TYR A CE2  1 
ATOM   4740  C CZ   . TYR A 1 357 ? -8.275  -6.469  18.437 1.00 15.45 ?  323  TYR A CZ   1 
ATOM   4741  O OH   . TYR A 1 357 ? -7.778  -7.215  17.372 1.00 16.53 ?  323  TYR A OH   1 
ATOM   4742  H H    . TYR A 1 357 ? -8.166  -5.988  23.457 1.00 14.73 ?  323  TYR A H    1 
ATOM   4743  H HA   . TYR A 1 357 ? -8.177  -4.022  22.708 1.00 13.63 ?  323  TYR A HA   1 
ATOM   4744  H HB2  . TYR A 1 357 ? -10.792 -4.371  21.785 1.00 16.71 ?  323  TYR A HB2  1 
ATOM   4745  H HB3  . TYR A 1 357 ? -9.830  -3.170  21.388 1.00 16.71 ?  323  TYR A HB3  1 
ATOM   4746  H HD1  . TYR A 1 357 ? -7.464  -4.171  20.528 1.00 17.18 ?  323  TYR A HD1  1 
ATOM   4747  H HD2  . TYR A 1 357 ? -10.978 -6.003  20.116 1.00 18.69 ?  323  TYR A HD2  1 
ATOM   4748  H HE1  . TYR A 1 357 ? -6.597  -5.383  18.757 1.00 17.57 ?  323  TYR A HE1  1 
ATOM   4749  H HE2  . TYR A 1 357 ? -10.087 -7.278  18.389 1.00 18.71 ?  323  TYR A HE2  1 
ATOM   4750  H HH   . TYR A 1 357 ? -6.948  -7.317  17.455 1.00 19.83 ?  323  TYR A HH   1 
ATOM   4751  N N    . SER A 1 358 ? -9.439  -3.848  25.303 1.00 11.49 ?  324  SER A N    1 
ATOM   4752  C CA   . SER A 1 358 ? -9.579  -2.965  26.463 1.00 11.34 ?  324  SER A CA   1 
ATOM   4753  C C    . SER A 1 358 ? -8.206  -2.574  26.959 1.00 12.48 ?  324  SER A C    1 
ATOM   4754  O O    . SER A 1 358 ? -7.312  -3.417  27.092 1.00 12.93 ?  324  SER A O    1 
ATOM   4755  C CB   . SER A 1 358 ? -10.277 -3.721  27.598 1.00 12.44 ?  324  SER A CB   1 
ATOM   4756  O OG   . SER A 1 358 ? -11.652 -4.017  27.310 1.00 12.84 ?  324  SER A OG   1 
ATOM   4757  H H    . SER A 1 358 ? -9.281  -4.667  25.512 1.00 13.79 ?  324  SER A H    1 
ATOM   4758  H HA   . SER A 1 358 ? -10.084 -2.173  26.220 1.00 13.60 ?  324  SER A HA   1 
ATOM   4759  H HB2  . SER A 1 358 ? -9.807  -4.557  27.744 1.00 14.93 ?  324  SER A HB2  1 
ATOM   4760  H HB3  . SER A 1 358 ? -10.241 -3.176  28.399 1.00 14.93 ?  324  SER A HB3  1 
ATOM   4761  H HG   . SER A 1 358 ? -11.777 -4.023  26.479 1.00 15.40 ?  324  SER A HG   1 
ATOM   4762  N N    . TYR A 1 359 ? -8.048  -1.286  27.262 1.00 12.83 ?  325  TYR A N    1 
ATOM   4763  C CA   . TYR A 1 359 ? -6.784  -0.690  27.644 1.00 11.94 ?  325  TYR A CA   1 
ATOM   4764  C C    . TYR A 1 359 ? -7.022  0.273   28.801 1.00 13.23 ?  325  TYR A C    1 
ATOM   4765  O O    . TYR A 1 359 ? -8.076  0.887   28.876 1.00 12.85 ?  325  TYR A O    1 
ATOM   4766  C CB   . TYR A 1 359 ? -6.173  0.111   26.470 1.00 11.34 ?  325  TYR A CB   1 
ATOM   4767  C CG   . TYR A 1 359 ? -6.011  -0.660  25.183 1.00 10.86 ?  325  TYR A CG   1 
ATOM   4768  C CD1  . TYR A 1 359 ? -7.036  -0.722  24.259 1.00 11.91 ?  325  TYR A CD1  1 
ATOM   4769  C CD2  . TYR A 1 359 ? -4.831  -1.293  24.896 1.00 13.23 ?  325  TYR A CD2  1 
ATOM   4770  C CE1  . TYR A 1 359 ? -6.872  -1.426  23.070 1.00 12.52 ?  325  TYR A CE1  1 
ATOM   4771  C CE2  . TYR A 1 359 ? -4.665  -2.032  23.695 1.00 11.35 ?  325  TYR A CE2  1 
ATOM   4772  C CZ   . TYR A 1 359 ? -5.705  -2.040  22.807 1.00 11.55 ?  325  TYR A CZ   1 
ATOM   4773  O OH   . TYR A 1 359 ? -5.622  -2.759  21.597 1.00 12.79 ?  325  TYR A OH   1 
ATOM   4774  H H    . TYR A 1 359 ? -8.693  -0.716  27.251 1.00 15.39 ?  325  TYR A H    1 
ATOM   4775  H HA   . TYR A 1 359 ? -6.167  -1.386  27.922 1.00 14.33 ?  325  TYR A HA   1 
ATOM   4776  H HB2  . TYR A 1 359 ? -6.750  0.869   26.283 1.00 13.61 ?  325  TYR A HB2  1 
ATOM   4777  H HB3  . TYR A 1 359 ? -5.293  0.422   26.735 1.00 13.61 ?  325  TYR A HB3  1 
ATOM   4778  H HD1  . TYR A 1 359 ? -7.841  -0.290  24.433 1.00 14.29 ?  325  TYR A HD1  1 
ATOM   4779  H HD2  . TYR A 1 359 ? -4.125  -1.237  25.499 1.00 15.87 ?  325  TYR A HD2  1 
ATOM   4780  H HE1  . TYR A 1 359 ? -7.571  -1.472  22.457 1.00 15.03 ?  325  TYR A HE1  1 
ATOM   4781  H HE2  . TYR A 1 359 ? -3.877  -2.494  23.519 1.00 13.62 ?  325  TYR A HE2  1 
ATOM   4782  H HH   . TYR A 1 359 ? -4.820  -2.824  21.357 1.00 15.35 ?  325  TYR A HH   1 
ATOM   4783  N N    . VAL A 1 360 ? -6.036  0.419   29.696 1.00 11.75 ?  326  VAL A N    1 
ATOM   4784  C CA   . VAL A 1 360 ? -6.212  1.228   30.909 1.00 12.25 ?  326  VAL A CA   1 
ATOM   4785  C C    . VAL A 1 360 ? -5.149  2.315   31.012 1.00 11.62 ?  326  VAL A C    1 
ATOM   4786  O O    . VAL A 1 360 ? -3.997  2.139   30.580 1.00 11.38 ?  326  VAL A O    1 
ATOM   4787  C CB   . VAL A 1 360 ? -6.176  0.298   32.164 1.00 13.12 ?  326  VAL A CB   1 
ATOM   4788  C CG1  . VAL A 1 360 ? -4.795  -0.321  32.406 1.00 13.99 ?  326  VAL A CG1  1 
ATOM   4789  C CG2  . VAL A 1 360 ? -6.658  1.021   33.420 1.00 12.40 ?  326  VAL A CG2  1 
ATOM   4790  H H    . VAL A 1 360 ? -5.258  0.061   29.621 1.00 14.10 ?  326  VAL A H    1 
ATOM   4791  H HA   . VAL A 1 360 ? -7.059  1.698   30.855 1.00 14.70 ?  326  VAL A HA   1 
ATOM   4792  H HB   . VAL A 1 360 ? -6.789  -0.431  31.977 1.00 15.74 ?  326  VAL A HB   1 
ATOM   4793  H HG11 . VAL A 1 360 ? -4.881  -1.045  33.045 1.00 16.79 ?  326  VAL A HG11 1 
ATOM   4794  H HG12 . VAL A 1 360 ? -4.450  -0.661  31.566 1.00 16.79 ?  326  VAL A HG12 1 
ATOM   4795  H HG13 . VAL A 1 360 ? -4.201  0.361   32.757 1.00 16.79 ?  326  VAL A HG13 1 
ATOM   4796  H HG21 . VAL A 1 360 ? -6.707  0.385   34.152 1.00 14.88 ?  326  VAL A HG21 1 
ATOM   4797  H HG22 . VAL A 1 360 ? -6.031  1.728   33.638 1.00 14.88 ?  326  VAL A HG22 1 
ATOM   4798  H HG23 . VAL A 1 360 ? -7.536  1.397   33.251 1.00 14.88 ?  326  VAL A HG23 1 
ATOM   4799  N N    . TYR A 1 361 ? -5.537  3.455   31.608 1.00 11.76 ?  327  TYR A N    1 
ATOM   4800  C CA   . TYR A 1 361 ? -4.590  4.520   31.951 1.00 11.78 ?  327  TYR A CA   1 
ATOM   4801  C C    . TYR A 1 361 ? -4.936  5.034   33.335 1.00 11.58 ?  327  TYR A C    1 
ATOM   4802  O O    . TYR A 1 361 ? -5.982  5.638   33.534 1.00 12.72 ?  327  TYR A O    1 
ATOM   4803  C CB   . TYR A 1 361 ? -4.660  5.655   30.934 1.00 11.46 ?  327  TYR A CB   1 
ATOM   4804  C CG   . TYR A 1 361 ? -3.640  6.787   31.113 1.00 12.77 ?  327  TYR A CG   1 
ATOM   4805  C CD1  . TYR A 1 361 ? -2.483  6.602   31.850 1.00 12.50 ?  327  TYR A CD1  1 
ATOM   4806  C CD2  . TYR A 1 361 ? -3.824  8.011   30.493 1.00 13.81 ?  327  TYR A CD2  1 
ATOM   4807  C CE1  . TYR A 1 361 ? -1.512  7.642   32.020 1.00 13.91 ?  327  TYR A CE1  1 
ATOM   4808  C CE2  . TYR A 1 361 ? -2.871  9.024   30.625 1.00 12.43 ?  327  TYR A CE2  1 
ATOM   4809  C CZ   . TYR A 1 361 ? -1.740  8.817   31.368 1.00 14.18 ?  327  TYR A CZ   1 
ATOM   4810  O OH   . TYR A 1 361 ? -0.753  9.815   31.524 1.00 14.74 ?  327  TYR A OH   1 
ATOM   4811  H H    . TYR A 1 361 ? -6.351  3.633   31.823 1.00 14.11 ?  327  TYR A H    1 
ATOM   4812  H HA   . TYR A 1 361 ? -3.690  4.159   31.969 1.00 14.14 ?  327  TYR A HA   1 
ATOM   4813  H HB2  . TYR A 1 361 ? -4.518  5.279   30.052 1.00 13.75 ?  327  TYR A HB2  1 
ATOM   4814  H HB3  . TYR A 1 361 ? -5.543  6.054   30.987 1.00 13.75 ?  327  TYR A HB3  1 
ATOM   4815  H HD1  . TYR A 1 361 ? -2.331  5.775   32.247 1.00 14.99 ?  327  TYR A HD1  1 
ATOM   4816  H HD2  . TYR A 1 361 ? -4.589  8.161   29.985 1.00 16.57 ?  327  TYR A HD2  1 
ATOM   4817  H HE1  . TYR A 1 361 ? -0.759  7.521   32.552 1.00 16.69 ?  327  TYR A HE1  1 
ATOM   4818  H HE2  . TYR A 1 361 ? -3.005  9.843   30.205 1.00 14.92 ?  327  TYR A HE2  1 
ATOM   4819  H HH   . TYR A 1 361 ? -0.972  10.505  31.098 1.00 17.69 ?  327  TYR A HH   1 
ATOM   4820  N N    . LEU A 1 362 ? -4.014  4.804   34.274 1.00 12.44 ?  328  LEU A N    1 
ATOM   4821  C CA   . LEU A 1 362 ? -4.080  5.363   35.630 1.00 12.66 ?  328  LEU A CA   1 
ATOM   4822  C C    . LEU A 1 362 ? -3.229  6.629   35.618 1.00 11.54 ?  328  LEU A C    1 
ATOM   4823  O O    . LEU A 1 362 ? -2.018  6.576   35.461 1.00 13.85 ?  328  LEU A O    1 
ATOM   4824  C CB   . LEU A 1 362 ? -3.573  4.363   36.669 1.00 13.55 ?  328  LEU A CB   1 
ATOM   4825  C CG   . LEU A 1 362 ? -4.163  2.954   36.615 1.00 16.12 ?  328  LEU A CG   1 
ATOM   4826  C CD1  . LEU A 1 362 ? -3.546  2.144   37.765 1.00 18.30 ?  328  LEU A CD1  1 
ATOM   4827  C CD2  . LEU A 1 362 ? -5.659  2.977   36.691 1.00 15.95 ?  328  LEU A CD2  1 
ATOM   4828  H H    . LEU A 1 362 ? -3.319  4.314   34.146 1.00 14.92 ?  328  LEU A H    1 
ATOM   4829  H HA   . LEU A 1 362 ? -4.996  5.580   35.862 1.00 15.19 ?  328  LEU A HA   1 
ATOM   4830  H HB2  . LEU A 1 362 ? -2.614  4.274   36.556 1.00 16.26 ?  328  LEU A HB2  1 
ATOM   4831  H HB3  . LEU A 1 362 ? -3.772  4.720   37.549 1.00 16.26 ?  328  LEU A HB3  1 
ATOM   4832  H HG   . LEU A 1 362 ? -3.952  2.529   35.769 1.00 19.35 ?  328  LEU A HG   1 
ATOM   4833  H HD11 . LEU A 1 362 ? -3.878  1.234   37.723 1.00 21.96 ?  328  LEU A HD11 1 
ATOM   4834  H HD12 . LEU A 1 362 ? -2.581  2.149   37.673 1.00 21.96 ?  328  LEU A HD12 1 
ATOM   4835  H HD13 . LEU A 1 362 ? -3.800  2.550   38.609 1.00 21.96 ?  328  LEU A HD13 1 
ATOM   4836  H HD21 . LEU A 1 362 ? -5.988  2.065   36.704 1.00 19.14 ?  328  LEU A HD21 1 
ATOM   4837  H HD22 . LEU A 1 362 ? -5.927  3.438   37.501 1.00 19.14 ?  328  LEU A HD22 1 
ATOM   4838  H HD23 . LEU A 1 362 ? -6.007  3.443   35.914 1.00 19.14 ?  328  LEU A HD23 1 
ATOM   4839  N N    . HIS A 1 363 ? -3.891  7.775   35.712 1.00 12.59 ?  329  HIS A N    1 
ATOM   4840  C CA   . HIS A 1 363 ? -3.244  9.026   35.334 1.00 11.74 ?  329  HIS A CA   1 
ATOM   4841  C C    . HIS A 1 363 ? -3.172  10.042  36.474 1.00 12.30 ?  329  HIS A C    1 
ATOM   4842  O O    . HIS A 1 363 ? -3.924  9.987   37.452 1.00 12.36 ?  329  HIS A O    1 
ATOM   4843  C CB   . HIS A 1 363 ? -3.946  9.677   34.144 1.00 13.34 ?  329  HIS A CB   1 
ATOM   4844  C CG   . HIS A 1 363 ? -5.322  10.147  34.451 1.00 12.89 ?  329  HIS A CG   1 
ATOM   4845  N ND1  . HIS A 1 363 ? -5.597  11.378  35.045 1.00 12.53 ?  329  HIS A ND1  1 
ATOM   4846  C CD2  . HIS A 1 363 ? -6.523  9.547   34.243 1.00 14.55 ?  329  HIS A CD2  1 
ATOM   4847  C CE1  . HIS A 1 363 ? -6.912  11.484  35.199 1.00 13.09 ?  329  HIS A CE1  1 
ATOM   4848  N NE2  . HIS A 1 363 ? -7.489  10.395  34.706 1.00 13.39 ?  329  HIS A NE2  1 
ATOM   4849  H H    . HIS A 1 363 ? -4.702  7.852   35.987 1.00 15.10 ?  329  HIS A H    1 
ATOM   4850  H HA   . HIS A 1 363 ? -2.329  8.804   35.104 1.00 14.08 ?  329  HIS A HA   1 
ATOM   4851  H HB2  . HIS A 1 363 ? -3.427  10.444  33.856 1.00 16.01 ?  329  HIS A HB2  1 
ATOM   4852  H HB3  . HIS A 1 363 ? -4.007  9.029   33.424 1.00 16.01 ?  329  HIS A HB3  1 
ATOM   4853  H HD2  . HIS A 1 363 ? -6.661  8.712   33.857 1.00 17.46 ?  329  HIS A HD2  1 
ATOM   4854  H HE1  . HIS A 1 363 ? -7.355  12.203  35.589 1.00 15.70 ?  329  HIS A HE1  1 
ATOM   4855  H HE2  . HIS A 1 363 ? -8.336  10.246  34.682 1.00 16.07 ?  329  HIS A HE2  1 
ATOM   4856  N N    . ASP A 1 364 ? -2.286  11.022  36.261 1.00 12.51 ?  330  ASP A N    1 
ATOM   4857  C CA   . ASP A 1 364 ? -2.213  12.250  37.066 1.00 10.89 ?  330  ASP A CA   1 
ATOM   4858  C C    . ASP A 1 364 ? -2.419  13.449  36.144 1.00 12.43 ?  330  ASP A C    1 
ATOM   4859  O O    . ASP A 1 364 ? -1.556  14.335  36.100 1.00 12.56 ?  330  ASP A O    1 
ATOM   4860  C CB   . ASP A 1 364 ? -0.904  12.299  37.837 1.00 14.09 ?  330  ASP A CB   1 
ATOM   4861  C CG   . ASP A 1 364 ? -0.784  13.510  38.775 1.00 12.26 ?  330  ASP A CG   1 
ATOM   4862  O OD1  . ASP A 1 364 ? -1.818  14.016  39.221 1.00 14.79 ?  330  ASP A OD1  1 
ATOM   4863  O OD2  . ASP A 1 364 ? 0.399   13.876  39.018 1.00 14.19 ?  330  ASP A OD2  1 
ATOM   4864  H H    . ASP A 1 364 ? -1.696  11.000  35.635 1.00 15.02 ?  330  ASP A H    1 
ATOM   4865  H HA   . ASP A 1 364 ? -2.909  12.279  37.741 1.00 13.07 ?  330  ASP A HA   1 
ATOM   4866  H HB2  . ASP A 1 364 ? -0.830  11.497  38.377 1.00 16.90 ?  330  ASP A HB2  1 
ATOM   4867  H HB3  . ASP A 1 364 ? -0.170  12.341  37.204 1.00 16.90 ?  330  ASP A HB3  1 
ATOM   4868  N N    . GLY A 1 365 ? -3.536  13.472  35.419 1.00 12.91 ?  331  GLY A N    1 
ATOM   4869  C CA   . GLY A 1 365 ? -3.828  14.496  34.453 1.00 12.32 ?  331  GLY A CA   1 
ATOM   4870  C C    . GLY A 1 365 ? -3.208  14.181  33.103 1.00 12.77 ?  331  GLY A C    1 
ATOM   4871  O O    . GLY A 1 365 ? -2.284  13.382  32.980 1.00 13.85 ?  331  GLY A O    1 
ATOM   4872  H H    . GLY A 1 365 ? -4.155  12.878  35.479 1.00 15.49 ?  331  GLY A H    1 
ATOM   4873  H HA2  . GLY A 1 365 ? -4.789  14.572  34.342 1.00 14.78 ?  331  GLY A HA2  1 
ATOM   4874  H HA3  . GLY A 1 365 ? -3.478  15.345  34.764 1.00 14.78 ?  331  GLY A HA3  1 
ATOM   4875  N N    . TYR A 1 366 ? -3.688  14.877  32.079 1.00 10.96 ?  332  TYR A N    1 
ATOM   4876  C CA   . TYR A 1 366 ? -3.242  14.573  30.726 1.00 11.41 ?  332  TYR A CA   1 
ATOM   4877  C C    . TYR A 1 366 ? -2.095  15.447  30.245 1.00 12.79 ?  332  TYR A C    1 
ATOM   4878  O O    . TYR A 1 366 ? -1.475  15.112  29.222 1.00 17.29 ?  332  TYR A O    1 
ATOM   4879  C CB   . TYR A 1 366 ? -4.421  14.612  29.777 1.00 11.96 ?  332  TYR A CB   1 
ATOM   4880  C CG   . TYR A 1 366 ? -5.511  13.619  30.129 1.00 11.48 ?  332  TYR A CG   1 
ATOM   4881  C CD1  . TYR A 1 366 ? -5.185  12.337  30.649 1.00 12.50 ?  332  TYR A CD1  1 
ATOM   4882  C CD2  . TYR A 1 366 ? -6.829  13.939  30.009 1.00 11.07 ?  332  TYR A CD2  1 
ATOM   4883  C CE1  . TYR A 1 366 ? -6.190  11.413  30.963 1.00 11.13 ?  332  TYR A CE1  1 
ATOM   4884  C CE2  . TYR A 1 366 ? -7.824  12.983  30.309 1.00 12.50 ?  332  TYR A CE2  1 
ATOM   4885  C CZ   . TYR A 1 366 ? -7.484  11.747  30.802 1.00 12.41 ?  332  TYR A CZ   1 
ATOM   4886  O OH   . TYR A 1 366 ? -8.438  10.804  31.166 1.00 13.79 ?  332  TYR A OH   1 
ATOM   4887  H H    . TYR A 1 366 ? -4.260  15.516  32.141 1.00 13.15 ?  332  TYR A H    1 
ATOM   4888  H HA   . TYR A 1 366 ? -2.897  13.667  30.699 1.00 13.70 ?  332  TYR A HA   1 
ATOM   4889  H HB2  . TYR A 1 366 ? -4.811  15.500  29.797 1.00 14.35 ?  332  TYR A HB2  1 
ATOM   4890  H HB3  . TYR A 1 366 ? -4.110  14.406  28.882 1.00 14.35 ?  332  TYR A HB3  1 
ATOM   4891  H HD1  . TYR A 1 366 ? -4.294  12.110  30.784 1.00 15.00 ?  332  TYR A HD1  1 
ATOM   4892  H HD2  . TYR A 1 366 ? -7.076  14.791  29.729 1.00 13.28 ?  332  TYR A HD2  1 
ATOM   4893  H HE1  . TYR A 1 366 ? -5.963  10.570  31.281 1.00 13.36 ?  332  TYR A HE1  1 
ATOM   4894  H HE2  . TYR A 1 366 ? -8.719  13.192  30.171 1.00 15.00 ?  332  TYR A HE2  1 
ATOM   4895  H HH   . TYR A 1 366 ? -9.203  11.066  30.938 1.00 16.54 ?  332  TYR A HH   1 
ATOM   4896  N N    . LEU A 1 367 ? -1.721  16.475  30.985 1.00 11.56 ?  333  LEU A N    1 
ATOM   4897  C CA   . LEU A 1 367 ? -0.572  17.296  30.656 1.00 11.92 ?  333  LEU A CA   1 
ATOM   4898  C C    . LEU A 1 367 ? 0.708   16.606  31.161 1.00 10.69 ?  333  LEU A C    1 
ATOM   4899  O O    . LEU A 1 367 ? 0.921   16.454  32.376 1.00 11.86 ?  333  LEU A O    1 
ATOM   4900  C CB   . LEU A 1 367 ? -0.741  18.690  31.283 1.00 11.78 ?  333  LEU A CB   1 
ATOM   4901  C CG   . LEU A 1 367 ? 0.466   19.611  31.083 1.00 11.04 ?  333  LEU A CG   1 
ATOM   4902  C CD1  . LEU A 1 367 ? 0.833   19.803  29.662 1.00 11.68 ?  333  LEU A CD1  1 
ATOM   4903  C CD2  . LEU A 1 367 ? 0.150   20.947  31.784 1.00 12.55 ?  333  LEU A CD2  1 
ATOM   4904  H H    . LEU A 1 367 ? -2.127  16.725  31.701 1.00 13.87 ?  333  LEU A H    1 
ATOM   4905  H HA   . LEU A 1 367 ? -0.494  17.399  29.695 1.00 14.31 ?  333  LEU A HA   1 
ATOM   4906  H HB2  . LEU A 1 367 ? -1.512  19.120  30.880 1.00 14.14 ?  333  LEU A HB2  1 
ATOM   4907  H HB3  . LEU A 1 367 ? -0.880  18.587  32.237 1.00 14.14 ?  333  LEU A HB3  1 
ATOM   4908  H HG   . LEU A 1 367 ? 1.255   19.203  31.474 1.00 13.25 ?  333  LEU A HG   1 
ATOM   4909  H HD11 . LEU A 1 367 ? 1.593   20.404  29.611 1.00 14.01 ?  333  LEU A HD11 1 
ATOM   4910  H HD12 . LEU A 1 367 ? 1.064   18.943  29.277 1.00 14.01 ?  333  LEU A HD12 1 
ATOM   4911  H HD13 . LEU A 1 367 ? 0.077   20.185  29.189 1.00 14.01 ?  333  LEU A HD13 1 
ATOM   4912  H HD21 . LEU A 1 367 ? 0.928   21.525  31.728 1.00 15.06 ?  333  LEU A HD21 1 
ATOM   4913  H HD22 . LEU A 1 367 ? -0.605  21.365  31.342 1.00 15.06 ?  333  LEU A HD22 1 
ATOM   4914  H HD23 . LEU A 1 367 ? -0.065  20.773  32.714 1.00 15.06 ?  333  LEU A HD23 1 
ATOM   4915  N N    . ALA A 1 368 ? 1.589   16.241  30.230 1.00 11.05 ?  334  ALA A N    1 
ATOM   4916  C CA   . ALA A 1 368 ? 2.749   15.429  30.576 1.00 10.91 ?  334  ALA A CA   1 
ATOM   4917  C C    . ALA A 1 368 ? 3.611   16.079  31.645 1.00 11.63 ?  334  ALA A C    1 
ATOM   4918  O O    . ALA A 1 368 ? 4.088   15.404  32.573 1.00 13.20 ?  334  ALA A O    1 
ATOM   4919  C CB   . ALA A 1 368 ? 3.576   15.199  29.323 1.00 13.76 ?  334  ALA A CB   1 
ATOM   4920  H H    . ALA A 1 368 ? 1.538   16.450  29.397 1.00 13.26 ?  334  ALA A H    1 
ATOM   4921  H HA   . ALA A 1 368 ? 2.439   14.580  30.928 1.00 13.09 ?  334  ALA A HA   1 
ATOM   4922  H HB1  . ALA A 1 368 ? 4.325   14.621  29.540 1.00 16.51 ?  334  ALA A HB1  1 
ATOM   4923  H HB2  . ALA A 1 368 ? 3.019   14.778  28.649 1.00 16.51 ?  334  ALA A HB2  1 
ATOM   4924  H HB3  . ALA A 1 368 ? 3.901   16.053  28.997 1.00 16.51 ?  334  ALA A HB3  1 
ATOM   4925  N N    . THR A 1 369 ? 3.820   17.375  31.541 1.00 11.47 ?  335  THR A N    1 
ATOM   4926  C CA   . THR A 1 369 ? 4.758   18.110  32.378 1.00 10.87 ?  335  THR A CA   1 
ATOM   4927  C C    . THR A 1 369 ? 4.214   18.367  33.763 1.00 13.33 ?  335  THR A C    1 
ATOM   4928  O O    . THR A 1 369 ? 4.975   18.838  34.627 1.00 14.18 ?  335  THR A O    1 
ATOM   4929  C CB   . THR A 1 369 ? 5.176   19.387  31.687 1.00 11.90 ?  335  THR A CB   1 
ATOM   4930  O OG1  . THR A 1 369 ? 4.026   20.092  31.183 1.00 12.12 ?  335  THR A OG1  1 
ATOM   4931  C CG2  . THR A 1 369 ? 6.098   19.116  30.540 1.00 14.18 ?  335  THR A CG2  1 
ATOM   4932  H H    . THR A 1 369 ? 3.417   17.878  30.971 1.00 13.76 ?  335  THR A H    1 
ATOM   4933  H HA   . THR A 1 369 ? 5.570   17.594  32.495 1.00 13.04 ?  335  THR A HA   1 
ATOM   4934  H HB   . THR A 1 369 ? 5.641   19.937  32.338 1.00 14.29 ?  335  THR A HB   1 
ATOM   4935  H HG1  . THR A 1 369 ? 3.428   20.125  31.773 1.00 14.54 ?  335  THR A HG1  1 
ATOM   4936  H HG21 . THR A 1 369 ? 6.358   19.950  30.119 1.00 17.01 ?  335  THR A HG21 1 
ATOM   4937  H HG22 . THR A 1 369 ? 6.894   18.660  30.855 1.00 17.01 ?  335  THR A HG22 1 
ATOM   4938  H HG23 . THR A 1 369 ? 5.654   18.557  29.883 1.00 17.01 ?  335  THR A HG23 1 
ATOM   4939  N N    . ASN A 1 370 ? 2.973   18.023  34.039 1.00 12.11 ?  336  ASN A N    1 
ATOM   4940  C CA   . ASN A 1 370 ? 2.381   18.208  35.361 1.00 12.61 ?  336  ASN A CA   1 
ATOM   4941  C C    . ASN A 1 370 ? 1.954   16.880  35.976 1.00 12.36 ?  336  ASN A C    1 
ATOM   4942  O O    . ASN A 1 370 ? 1.233   16.863  36.977 1.00 13.99 ?  336  ASN A O    1 
ATOM   4943  C CB   . ASN A 1 370 ? 1.214   19.211  35.307 1.00 13.43 ?  336  ASN A CB   1 
ATOM   4944  C CG   . ASN A 1 370 ? 0.845   19.768  36.682 1.00 15.20 ?  336  ASN A CG   1 
ATOM   4945  O OD1  . ASN A 1 370 ? 1.708   20.051  37.491 1.00 17.21 ?  336  ASN A OD1  1 
ATOM   4946  N ND2  . ASN A 1 370 ? -0.446  19.924  36.903 1.00 16.97 ?  336  ASN A ND2  1 
ATOM   4947  H H    . ASN A 1 370 ? 2.434   17.672  33.467 1.00 14.53 ?  336  ASN A H    1 
ATOM   4948  H HA   . ASN A 1 370 ? 3.040   18.601  35.954 1.00 15.13 ?  336  ASN A HA   1 
ATOM   4949  H HB2  . ASN A 1 370 ? 1.464   19.956  34.740 1.00 16.12 ?  336  ASN A HB2  1 
ATOM   4950  H HB3  . ASN A 1 370 ? 0.432   18.766  34.945 1.00 16.12 ?  336  ASN A HB3  1 
ATOM   4951  H HD21 . ASN A 1 370 ? -0.719  20.233  37.657 1.00 20.36 ?  336  ASN A HD21 1 
ATOM   4952  H HD22 . ASN A 1 370 ? -1.015  19.716  36.292 1.00 20.36 ?  336  ASN A HD22 1 
ATOM   4953  N N    . SER A 1 371 ? 2.350   15.751  35.388 1.00 12.33 ?  337  SER A N    1 
ATOM   4954  C CA   . SER A 1 371 ? 1.939   14.426  35.841 1.00 12.47 ?  337  SER A CA   1 
ATOM   4955  C C    . SER A 1 371 ? 3.082   13.695  36.533 1.00 13.33 ?  337  SER A C    1 
ATOM   4956  O O    . SER A 1 371 ? 4.149   13.518  35.949 1.00 14.04 ?  337  SER A O    1 
ATOM   4957  C CB   . SER A 1 371 ? 1.499   13.582  34.634 1.00 12.35 ?  337  SER A CB   1 
ATOM   4958  O OG   . SER A 1 371 ? 1.418   12.229  35.049 1.00 12.78 ?  337  SER A OG   1 
ATOM   4959  H H    . SER A 1 371 ? 2.872   15.729  34.704 1.00 14.79 ?  337  SER A H    1 
ATOM   4960  H HA   . SER A 1 371 ? 1.218   14.534  36.481 1.00 14.96 ?  337  SER A HA   1 
ATOM   4961  H HB2  . SER A 1 371 ? 0.630   13.881  34.325 1.00 14.82 ?  337  SER A HB2  1 
ATOM   4962  H HB3  . SER A 1 371 ? 2.152   13.666  33.921 1.00 14.82 ?  337  SER A HB3  1 
ATOM   4963  H HG   . SER A 1 371 ? 0.937   11.793  34.517 1.00 15.33 ?  337  SER A HG   1 
ATOM   4964  N N    . ALA A 1 372 ? 2.818   13.185  37.747 1.00 13.75 ?  338  ALA A N    1 
ATOM   4965  C CA   . ALA A 1 372 ? 3.821   12.418  38.493 1.00 14.81 ?  338  ALA A CA   1 
ATOM   4966  C C    . ALA A 1 372 ? 4.031   11.034  37.924 1.00 16.29 ?  338  ALA A C    1 
ATOM   4967  O O    . ALA A 1 372 ? 5.010   10.381  38.323 1.00 17.58 ?  338  ALA A O    1 
ATOM   4968  C CB   . ALA A 1 372 ? 3.360   12.291  39.944 1.00 18.53 ?  338  ALA A CB   1 
ATOM   4969  H H    . ALA A 1 372 ? 2.066   13.270  38.157 1.00 16.50 ?  338  ALA A H    1 
ATOM   4970  H HA   . ALA A 1 372 ? 4.669   12.888  38.460 1.00 17.77 ?  338  ALA A HA   1 
ATOM   4971  H HB1  . ALA A 1 372 ? 4.027   11.796  40.445 1.00 22.23 ?  338  ALA A HB1  1 
ATOM   4972  H HB2  . ALA A 1 372 ? 3.254   13.178  40.320 1.00 22.23 ?  338  ALA A HB2  1 
ATOM   4973  H HB3  . ALA A 1 372 ? 2.512   11.819  39.965 1.00 22.23 ?  338  ALA A HB3  1 
ATOM   4974  N N    . VAL A 1 373 ? 3.131   10.530  37.076 1.00 14.12 ?  339  VAL A N    1 
ATOM   4975  C CA   . VAL A 1 373 ? 3.319   9.205   36.491 1.00 15.94 ?  339  VAL A CA   1 
ATOM   4976  C C    . VAL A 1 373 ? 3.887   9.253   35.087 1.00 15.47 ?  339  VAL A C    1 
ATOM   4977  O O    . VAL A 1 373 ? 4.234   8.209   34.537 1.00 15.58 ?  339  VAL A O    1 
ATOM   4978  C CB   . VAL A 1 373 ? 2.040   8.344   36.537 1.00 15.46 ?  339  VAL A CB   1 
ATOM   4979  C CG1  . VAL A 1 373 ? 1.631   8.064   37.990 1.00 19.14 ?  339  VAL A CG1  1 
ATOM   4980  C CG2  . VAL A 1 373 ? 0.899   8.923   35.725 1.00 15.03 ?  339  VAL A CG2  1 
ATOM   4981  H H    . VAL A 1 373 ? 2.413   10.932  36.828 1.00 16.95 ?  339  VAL A H    1 
ATOM   4982  H HA   . VAL A 1 373 ? 3.969   8.743   37.043 1.00 19.13 ?  339  VAL A HA   1 
ATOM   4983  H HB   . VAL A 1 373 ? 2.245   7.496   36.113 1.00 18.55 ?  339  VAL A HB   1 
ATOM   4984  H HG11 . VAL A 1 373 ? 0.797   7.568   37.994 1.00 22.97 ?  339  VAL A HG11 1 
ATOM   4985  H HG12 . VAL A 1 373 ? 2.328   7.543   38.420 1.00 22.97 ?  339  VAL A HG12 1 
ATOM   4986  H HG13 . VAL A 1 373 ? 1.516   8.908   38.455 1.00 22.97 ?  339  VAL A HG13 1 
ATOM   4987  H HG21 . VAL A 1 373 ? 0.136   8.327   35.783 1.00 18.04 ?  339  VAL A HG21 1 
ATOM   4988  H HG22 . VAL A 1 373 ? 0.666   9.794   36.084 1.00 18.04 ?  339  VAL A HG22 1 
ATOM   4989  H HG23 . VAL A 1 373 ? 1.181   9.011   34.801 1.00 18.04 ?  339  VAL A HG23 1 
ATOM   4990  N N    . TRP A 1 374 ? 4.049   10.433  34.507 1.00 15.03 ?  340  TRP A N    1 
ATOM   4991  C CA   . TRP A 1 374 ? 4.624   10.545  33.177 1.00 13.67 ?  340  TRP A CA   1 
ATOM   4992  C C    . TRP A 1 374 ? 6.001   9.921   33.166 1.00 15.69 ?  340  TRP A C    1 
ATOM   4993  O O    . TRP A 1 374 ? 6.806   10.134  34.075 1.00 18.02 ?  340  TRP A O    1 
ATOM   4994  C CB   . TRP A 1 374 ? 4.742   12.031  32.823 1.00 17.92 ?  340  TRP A CB   1 
ATOM   4995  C CG   . TRP A 1 374 ? 5.363   12.333  31.506 1.00 15.69 ?  340  TRP A CG   1 
ATOM   4996  C CD1  . TRP A 1 374 ? 6.497   13.052  31.309 1.00 16.72 ?  340  TRP A CD1  1 
ATOM   4997  C CD2  . TRP A 1 374 ? 4.883   11.941  30.215 1.00 14.34 ?  340  TRP A CD2  1 
ATOM   4998  N NE1  . TRP A 1 374 ? 6.753   13.146  29.950 1.00 15.21 ?  340  TRP A NE1  1 
ATOM   4999  C CE2  . TRP A 1 374 ? 5.784   12.468  29.263 1.00 13.11 ?  340  TRP A CE2  1 
ATOM   5000  C CE3  . TRP A 1 374 ? 3.783   11.219  29.762 1.00 15.17 ?  340  TRP A CE3  1 
ATOM   5001  C CZ2  . TRP A 1 374 ? 5.611   12.289  27.890 1.00 14.07 ?  340  TRP A CZ2  1 
ATOM   5002  C CZ3  . TRP A 1 374 ? 3.629   11.001  28.414 1.00 14.15 ?  340  TRP A CZ3  1 
ATOM   5003  C CH2  . TRP A 1 374 ? 4.520   11.572  27.468 1.00 14.78 ?  340  TRP A CH2  1 
ATOM   5004  H H    . TRP A 1 374 ? 3.834   11.186  34.863 1.00 18.03 ?  340  TRP A H    1 
ATOM   5005  H HA   . TRP A 1 374 ? 4.067   10.095  32.523 1.00 16.40 ?  340  TRP A HA   1 
ATOM   5006  H HB2  . TRP A 1 374 ? 3.850   12.414  32.815 1.00 21.50 ?  340  TRP A HB2  1 
ATOM   5007  H HB3  . TRP A 1 374 ? 5.282   12.464  33.502 1.00 21.50 ?  340  TRP A HB3  1 
ATOM   5008  H HD1  . TRP A 1 374 ? 7.021   13.423  31.981 1.00 20.07 ?  340  TRP A HD1  1 
ATOM   5009  H HE1  . TRP A 1 374 ? 7.416   13.564  29.596 1.00 18.26 ?  340  TRP A HE1  1 
ATOM   5010  H HE3  . TRP A 1 374 ? 3.158   10.887  30.366 1.00 18.21 ?  340  TRP A HE3  1 
ATOM   5011  H HZ2  . TRP A 1 374 ? 6.217   12.644  27.281 1.00 16.89 ?  340  TRP A HZ2  1 
ATOM   5012  H HZ3  . TRP A 1 374 ? 2.927   10.468  28.115 1.00 16.98 ?  340  TRP A HZ3  1 
ATOM   5013  H HH2  . TRP A 1 374 ? 4.364   11.461  26.558 1.00 17.73 ?  340  TRP A HH2  1 
ATOM   5014  N N    . LEU A 1 375 ? 6.271   9.127   32.124 1.00 14.97 ?  341  LEU A N    1 
ATOM   5015  C CA   . LEU A 1 375 ? 7.527   8.415   31.887 1.00 18.14 ?  341  LEU A CA   1 
ATOM   5016  C C    . LEU A 1 375 ? 7.709   7.225   32.813 1.00 20.33 ?  341  LEU A C    1 
ATOM   5017  O O    . LEU A 1 375 ? 8.785   6.607   32.790 1.00 29.90 ?  341  LEU A O    1 
ATOM   5018  C CB   . LEU A 1 375 ? 8.757   9.329   31.922 1.00 18.95 ?  341  LEU A CB   1 
ATOM   5019  C CG   . LEU A 1 375 ? 8.841   10.291  30.756 1.00 19.19 ?  341  LEU A CG   1 
ATOM   5020  C CD1  . LEU A 1 375 ? 9.933   11.357  30.913 1.00 23.61 ?  341  LEU A CD1  1 
ATOM   5021  C CD2  . LEU A 1 375 ? 9.088   9.517   29.499 1.00 23.98 ?  341  LEU A CD2  1 
ATOM   5022  H H    . LEU A 1 375 ? 5.699   8.978   31.499 1.00 17.97 ?  341  LEU A H    1 
ATOM   5023  H HA   . LEU A 1 375 ? 7.491   8.063   30.984 1.00 21.76 ?  341  LEU A HA   1 
ATOM   5024  H HB2  . LEU A 1 375 ? 8.731   9.854   32.738 1.00 22.75 ?  341  LEU A HB2  1 
ATOM   5025  H HB3  . LEU A 1 375 ? 9.555   8.777   31.908 1.00 22.75 ?  341  LEU A HB3  1 
ATOM   5026  H HG   . LEU A 1 375 ? 7.998   10.769  30.714 1.00 23.02 ?  341  LEU A HG   1 
ATOM   5027  H HD11 . LEU A 1 375 ? 9.901   11.957  30.152 1.00 28.34 ?  341  LEU A HD11 1 
ATOM   5028  H HD12 . LEU A 1 375 ? 9.776   11.852  31.732 1.00 28.34 ?  341  LEU A HD12 1 
ATOM   5029  H HD13 . LEU A 1 375 ? 10.798  10.919  30.953 1.00 28.34 ?  341  LEU A HD13 1 
ATOM   5030  H HD21 . LEU A 1 375 ? 9.408   10.124  28.813 1.00 28.78 ?  341  LEU A HD21 1 
ATOM   5031  H HD22 . LEU A 1 375 ? 9.756   8.835   29.675 1.00 28.78 ?  341  LEU A HD22 1 
ATOM   5032  H HD23 . LEU A 1 375 ? 8.259   9.103   29.215 1.00 28.78 ?  341  LEU A HD23 1 
ATOM   5033  N N    . HIS A 1 376 ? 6.716   6.850   33.599 1.00 15.90 ?  342  HIS A N    1 
ATOM   5034  C CA   A HIS A 1 376 ? 6.883   5.818   34.604 0.59 17.72 ?  342  HIS A CA   1 
ATOM   5035  C CA   B HIS A 1 376 ? 6.877   5.808   34.610 0.41 17.78 ?  342  HIS A CA   1 
ATOM   5036  C C    . HIS A 1 376 ? 5.966   4.637   34.309 1.00 17.20 ?  342  HIS A C    1 
ATOM   5037  O O    . HIS A 1 376 ? 4.986   4.749   33.562 1.00 22.07 ?  342  HIS A O    1 
ATOM   5038  C CB   A HIS A 1 376 ? 6.677   6.422   36.009 0.59 21.78 ?  342  HIS A CB   1 
ATOM   5039  C CB   B HIS A 1 376 ? 6.590   6.317   36.040 0.41 21.32 ?  342  HIS A CB   1 
ATOM   5040  C CG   A HIS A 1 376 ? 7.687   7.493   36.364 0.59 18.96 ?  342  HIS A CG   1 
ATOM   5041  C CG   B HIS A 1 376 ? 6.504   5.236   37.087 0.41 19.25 ?  342  HIS A CG   1 
ATOM   5042  N ND1  A HIS A 1 376 ? 9.043   7.242   36.458 0.59 23.06 ?  342  HIS A ND1  1 
ATOM   5043  N ND1  B HIS A 1 376 ? 5.318   4.616   37.421 0.41 29.51 ?  342  HIS A ND1  1 
ATOM   5044  C CD2  A HIS A 1 376 ? 7.539   8.822   36.622 0.59 16.82 ?  342  HIS A CD2  1 
ATOM   5045  C CD2  B HIS A 1 376 ? 7.449   4.688   37.892 0.41 22.62 ?  342  HIS A CD2  1 
ATOM   5046  C CE1  A HIS A 1 376 ? 9.679   8.360   36.772 0.59 23.76 ?  342  HIS A CE1  1 
ATOM   5047  C CE1  B HIS A 1 376 ? 5.535   3.733   38.379 0.41 24.93 ?  342  HIS A CE1  1 
ATOM   5048  N NE2  A HIS A 1 376 ? 8.793   9.331   36.872 0.59 25.45 ?  342  HIS A NE2  1 
ATOM   5049  N NE2  B HIS A 1 376 ? 6.820   3.738   38.673 0.41 17.99 ?  342  HIS A NE2  1 
ATOM   5050  H H    . HIS A 1 376 ? 5.924   7.185   33.566 1.00 19.08 ?  342  HIS A H    1 
ATOM   5051  H HA   . HIS A 1 376 ? 7.779   5.446   34.586 1.00 21.34 ?  342  HIS A HA   1 
ATOM   5052  H HB2  A HIS A 1 376 ? 5.794   6.821   36.050 0.59 26.14 ?  342  HIS A HB2  1 
ATOM   5053  H HB2  B HIS A 1 376 ? 7.302   6.921   36.302 0.41 25.59 ?  342  HIS A HB2  1 
ATOM   5054  H HB3  A HIS A 1 376 ? 6.752   5.714   36.667 0.59 26.14 ?  342  HIS A HB3  1 
ATOM   5055  H HB3  B HIS A 1 376 ? 5.741   6.787   36.035 0.41 25.59 ?  342  HIS A HB3  1 
ATOM   5056  H HD1  A HIS A 1 376 ? 9.416   6.477   36.332 0.59 27.67 ?  342  HIS A HD1  1 
ATOM   5057  H HD1  B HIS A 1 376 ? 4.554   4.779   37.061 0.41 35.41 ?  342  HIS A HD1  1 
ATOM   5058  H HD2  A HIS A 1 376 ? 6.739   9.297   36.627 0.59 20.18 ?  342  HIS A HD2  1 
ATOM   5059  H HD2  B HIS A 1 376 ? 8.351   4.912   37.914 0.41 27.14 ?  342  HIS A HD2  1 
ATOM   5060  H HE1  A HIS A 1 376 ? 10.596  8.445   36.900 0.59 28.51 ?  342  HIS A HE1  1 
ATOM   5061  H HE1  B HIS A 1 376 ? 4.889   3.197   38.780 0.41 29.92 ?  342  HIS A HE1  1 
ATOM   5062  N N    . GLN A 1 377 ? 6.317   3.482   34.863 1.00 20.09 ?  343  GLN A N    1 
ATOM   5063  C CA   . GLN A 1 377 ? 5.488   2.284   34.738 1.00 24.35 ?  343  GLN A CA   1 
ATOM   5064  C C    . GLN A 1 377 ? 5.471   1.538   36.062 1.00 28.71 ?  343  GLN A C    1 
ATOM   5065  O O    . GLN A 1 377 ? 6.536   1.160   36.586 1.00 29.53 ?  343  GLN A O    1 
ATOM   5066  C CB   . GLN A 1 377 ? 5.980   1.344   33.638 1.00 36.41 ?  343  GLN A CB   1 
ATOM   5067  C CG   . GLN A 1 377 ? 7.339   0.755   33.872 1.00 36.48 ?  343  GLN A CG   1 
ATOM   5068  C CD   . GLN A 1 377 ? 7.744   -0.225  32.779 1.00 52.34 ?  343  GLN A CD   1 
ATOM   5069  O OE1  . GLN A 1 377 ? 7.191   -0.224  31.681 1.00 67.32 ?  343  GLN A OE1  1 
ATOM   5070  H H    . GLN A 1 377 ? 7.036   3.364   35.321 1.00 24.10 ?  343  GLN A H    1 
ATOM   5071  H HA   . GLN A 1 377 ? 4.588   2.574   34.522 1.00 29.22 ?  343  GLN A HA   1 
ATOM   5072  H HB2  . GLN A 1 377 ? 5.353   0.608   33.559 1.00 43.69 ?  343  GLN A HB2  1 
ATOM   5073  H HB3  . GLN A 1 377 ? 6.017   1.839   32.805 1.00 43.69 ?  343  GLN A HB3  1 
ATOM   5074  H HG2  . GLN A 1 377 ? 7.994   1.470   33.895 1.00 43.77 ?  343  GLN A HG2  1 
ATOM   5075  H HG3  . GLN A 1 377 ? 7.337   0.280   34.718 1.00 43.77 ?  343  GLN A HG3  1 
ATOM   5076  N N    . PHE A 1 378 ? 4.268   1.310   36.579 1.00 20.16 ?  344  PHE A N    1 
ATOM   5077  C CA   . PHE A 1 378 ? 4.097   0.572   37.827 1.00 19.74 ?  344  PHE A CA   1 
ATOM   5078  C C    . PHE A 1 378 ? 4.486   -0.891  37.614 1.00 20.60 ?  344  PHE A C    1 
ATOM   5079  O O    . PHE A 1 378 ? 4.449   -1.410  36.501 1.00 18.19 ?  344  PHE A O    1 
ATOM   5080  C CB   . PHE A 1 378 ? 2.654   0.662   38.289 1.00 19.02 ?  344  PHE A CB   1 
ATOM   5081  C CG   . PHE A 1 378 ? 2.265   2.045   38.765 1.00 19.06 ?  344  PHE A CG   1 
ATOM   5082  C CD1  . PHE A 1 378 ? 2.727   2.506   39.979 1.00 20.50 ?  344  PHE A CD1  1 
ATOM   5083  C CD2  . PHE A 1 378 ? 1.455   2.865   37.990 1.00 22.21 ?  344  PHE A CD2  1 
ATOM   5084  C CE1  . PHE A 1 378 ? 2.386   3.784   40.445 1.00 24.38 ?  344  PHE A CE1  1 
ATOM   5085  C CE2  . PHE A 1 378 ? 1.109   4.142   38.444 1.00 24.21 ?  344  PHE A CE2  1 
ATOM   5086  C CZ   . PHE A 1 378 ? 1.580   4.593   39.670 1.00 21.25 ?  344  PHE A CZ   1 
ATOM   5087  H H    . PHE A 1 378 ? 3.529   1.572   36.225 1.00 24.19 ?  344  PHE A H    1 
ATOM   5088  H HA   . PHE A 1 378 ? 4.660   0.948   38.521 1.00 23.69 ?  344  PHE A HA   1 
ATOM   5089  H HB2  . PHE A 1 378 ? 2.072   0.426   37.550 1.00 22.83 ?  344  PHE A HB2  1 
ATOM   5090  H HB3  . PHE A 1 378 ? 2.522   0.045   39.026 1.00 22.83 ?  344  PHE A HB3  1 
ATOM   5091  H HD1  . PHE A 1 378 ? 3.274   1.960   40.497 1.00 24.60 ?  344  PHE A HD1  1 
ATOM   5092  H HD2  . PHE A 1 378 ? 1.142   2.563   37.168 1.00 26.65 ?  344  PHE A HD2  1 
ATOM   5093  H HE1  . PHE A 1 378 ? 2.699   4.083   41.268 1.00 29.25 ?  344  PHE A HE1  1 
ATOM   5094  H HE2  . PHE A 1 378 ? 0.563   4.688   37.925 1.00 29.06 ?  344  PHE A HE2  1 
ATOM   5095  H HZ   . PHE A 1 378 ? 1.352   5.443   39.970 1.00 25.50 ?  344  PHE A HZ   1 
ATOM   5096  N N    . ASP A 1 379 ? 4.932   -1.543  38.693 1.00 18.69 ?  345  ASP A N    1 
ATOM   5097  C CA   . ASP A 1 379 ? 5.350   -2.936  38.560 1.00 17.73 ?  345  ASP A CA   1 
ATOM   5098  C C    . ASP A 1 379 ? 4.221   -3.825  38.066 1.00 17.50 ?  345  ASP A C    1 
ATOM   5099  O O    . ASP A 1 379 ? 4.475   -4.814  37.364 1.00 17.93 ?  345  ASP A O    1 
ATOM   5100  C CB   . ASP A 1 379 ? 5.856   -3.453  39.897 1.00 22.56 ?  345  ASP A CB   1 
ATOM   5101  C CG   . ASP A 1 379 ? 7.175   -2.816  40.310 1.00 31.34 ?  345  ASP A CG   1 
ATOM   5102  O OD1  . ASP A 1 379 ? 7.875   -2.219  39.457 1.00 29.03 ?  345  ASP A OD1  1 
ATOM   5103  O OD2  . ASP A 1 379 ? 7.514   -2.944  41.503 1.00 36.77 ?  345  ASP A OD2  1 
ATOM   5104  H H    . ASP A 1 379 ? 4.998   -1.212  39.484 1.00 22.43 ?  345  ASP A H    1 
ATOM   5105  H HA   . ASP A 1 379 ? 6.072   -2.978  37.914 1.00 21.28 ?  345  ASP A HA   1 
ATOM   5106  H HB2  . ASP A 1 379 ? 5.199   -3.255  40.582 1.00 27.07 ?  345  ASP A HB2  1 
ATOM   5107  H HB3  . ASP A 1 379 ? 5.992   -4.412  39.835 1.00 27.07 ?  345  ASP A HB3  1 
ATOM   5108  N N    . GLN A 1 380 ? 2.978   -3.474  38.405 1.00 16.45 ?  346  GLN A N    1 
ATOM   5109  C CA   . GLN A 1 380 ? 1.803   -4.209  37.961 1.00 16.06 ?  346  GLN A CA   1 
ATOM   5110  C C    . GLN A 1 380 ? 1.686   -4.242  36.446 1.00 17.36 ?  346  GLN A C    1 
ATOM   5111  O O    . GLN A 1 380 ? 0.956   -5.082  35.908 1.00 20.49 ?  346  GLN A O    1 
ATOM   5112  C CB   . GLN A 1 380 ? 0.549   -3.523  38.546 1.00 16.44 ?  346  GLN A CB   1 
ATOM   5113  C CG   . GLN A 1 380 ? 0.384   -3.603  40.079 1.00 15.03 ?  346  GLN A CG   1 
ATOM   5114  C CD   . GLN A 1 380 ? 1.064   -2.465  40.822 1.00 14.45 ?  346  GLN A CD   1 
ATOM   5115  O OE1  . GLN A 1 380 ? 2.008   -1.886  40.324 1.00 17.54 ?  346  GLN A OE1  1 
ATOM   5116  N NE2  . GLN A 1 380 ? 0.578   -2.180  42.016 1.00 18.67 ?  346  GLN A NE2  1 
ATOM   5117  H H    . GLN A 1 380 ? 2.787   -2.798  38.902 1.00 19.74 ?  346  GLN A H    1 
ATOM   5118  H HA   . GLN A 1 380 ? 1.855   -5.124  38.279 1.00 19.28 ?  346  GLN A HA   1 
ATOM   5119  H HB2  . GLN A 1 380 ? 0.580   -2.583  38.310 1.00 19.73 ?  346  GLN A HB2  1 
ATOM   5120  H HB3  . GLN A 1 380 ? -0.234  -3.938  38.152 1.00 19.73 ?  346  GLN A HB3  1 
ATOM   5121  H HG2  . GLN A 1 380 ? -0.561  -3.575  40.295 1.00 18.03 ?  346  GLN A HG2  1 
ATOM   5122  H HG3  . GLN A 1 380 ? 0.771   -4.435  40.393 1.00 18.03 ?  346  GLN A HG3  1 
ATOM   5123  H HE21 . GLN A 1 380 ? -0.085  -2.629  42.328 1.00 22.41 ?  346  GLN A HE21 1 
ATOM   5124  H HE22 . GLN A 1 380 ? 0.925   -1.545  42.480 1.00 22.41 ?  346  GLN A HE22 1 
ATOM   5125  N N    . TYR A 1 381 ? 2.345   -3.338  35.739 1.00 16.25 ?  347  TYR A N    1 
ATOM   5126  C CA   . TYR A 1 381 ? 2.262   -3.304  34.293 1.00 14.91 ?  347  TYR A CA   1 
ATOM   5127  C C    . TYR A 1 381 ? 3.230   -4.258  33.637 1.00 17.18 ?  347  TYR A C    1 
ATOM   5128  O O    . TYR A 1 381 ? 3.112   -4.502  32.435 1.00 19.20 ?  347  TYR A O    1 
ATOM   5129  C CB   . TYR A 1 381 ? 2.567   -1.891  33.775 1.00 15.22 ?  347  TYR A CB   1 
ATOM   5130  C CG   . TYR A 1 381 ? 1.644   -0.768  34.220 1.00 16.28 ?  347  TYR A CG   1 
ATOM   5131  C CD1  . TYR A 1 381 ? 0.475   -1.006  34.921 1.00 16.18 ?  347  TYR A CD1  1 
ATOM   5132  C CD2  . TYR A 1 381 ? 1.946   0.544   33.892 1.00 16.77 ?  347  TYR A CD2  1 
ATOM   5133  C CE1  . TYR A 1 381 ? -0.364  0.044   35.320 1.00 19.55 ?  347  TYR A CE1  1 
ATOM   5134  C CE2  . TYR A 1 381 ? 1.123   1.590   34.277 1.00 19.86 ?  347  TYR A CE2  1 
ATOM   5135  C CZ   . TYR A 1 381 ? -0.016  1.330   34.990 1.00 18.86 ?  347  TYR A CZ   1 
ATOM   5136  O OH   . TYR A 1 381 ? -0.855  2.372   35.368 1.00 24.82 ?  347  TYR A OH   1 
ATOM   5137  H H    . TYR A 1 381 ? 2.850   -2.729  36.077 1.00 19.51 ?  347  TYR A H    1 
ATOM   5138  H HA   . TYR A 1 381 ? 1.357   -3.541  34.037 1.00 17.90 ?  347  TYR A HA   1 
ATOM   5139  H HB2  . TYR A 1 381 ? 3.460   -1.653  34.069 1.00 18.26 ?  347  TYR A HB2  1 
ATOM   5140  H HB3  . TYR A 1 381 ? 2.532   -1.915  32.806 1.00 18.26 ?  347  TYR A HB3  1 
ATOM   5141  H HD1  . TYR A 1 381 ? 0.241   -1.881  35.133 1.00 19.42 ?  347  TYR A HD1  1 
ATOM   5142  H HD2  . TYR A 1 381 ? 2.716   0.726   33.404 1.00 20.13 ?  347  TYR A HD2  1 
ATOM   5143  H HE1  . TYR A 1 381 ? -1.143  -0.128  35.800 1.00 23.47 ?  347  TYR A HE1  1 
ATOM   5144  H HE2  . TYR A 1 381 ? 1.343   2.465   34.052 1.00 23.83 ?  347  TYR A HE2  1 
ATOM   5145  H HH   . TYR A 1 381 ? -0.602  3.089   35.010 1.00 29.79 ?  347  TYR A HH   1 
ATOM   5146  N N    . LYS A 1 382 ? 4.214   -4.774  34.384 1.00 17.21 ?  348  LYS A N    1 
ATOM   5147  C CA   . LYS A 1 382 ? 5.262   -5.630  33.853 1.00 19.96 ?  348  LYS A CA   1 
ATOM   5148  C C    . LYS A 1 382 ? 5.033   -7.103  34.154 1.00 16.91 ?  348  LYS A C    1 
ATOM   5149  O O    . LYS A 1 382 ? 5.634   -7.952  33.489 1.00 20.06 ?  348  LYS A O    1 
ATOM   5150  C CB   . LYS A 1 382 ? 6.617   -5.286  34.493 1.00 22.29 ?  348  LYS A CB   1 
ATOM   5151  C CG   . LYS A 1 382 ? 6.978   -3.809  34.576 1.00 29.09 ?  348  LYS A CG   1 
ATOM   5152  C CD   . LYS A 1 382 ? 8.190   -3.597  35.517 1.00 35.62 ?  348  LYS A CD   1 
ATOM   5153  C CE   . LYS A 1 382 ? 8.429   -2.114  35.800 1.00 45.17 ?  348  LYS A CE   1 
ATOM   5154  N NZ   . LYS A 1 382 ? 9.748   -1.862  36.455 1.00 46.90 ?  348  LYS A NZ   1 
ATOM   5155  H H    . LYS A 1 382 ? 4.293   -4.635  35.229 1.00 20.65 ?  348  LYS A H    1 
ATOM   5156  H HA   . LYS A 1 382 ? 5.302   -5.483  32.895 1.00 23.95 ?  348  LYS A HA   1 
ATOM   5157  H HB2  . LYS A 1 382 ? 6.616   -5.628  35.400 1.00 26.75 ?  348  LYS A HB2  1 
ATOM   5158  H HB3  . LYS A 1 382 ? 7.313   -5.719  33.975 1.00 26.75 ?  348  LYS A HB3  1 
ATOM   5159  H HG2  . LYS A 1 382 ? 7.211   -3.482  33.693 1.00 34.91 ?  348  LYS A HG2  1 
ATOM   5160  H HG3  . LYS A 1 382 ? 6.224   -3.310  34.926 1.00 34.91 ?  348  LYS A HG3  1 
ATOM   5161  H HD2  . LYS A 1 382 ? 8.023   -4.045  36.361 1.00 42.75 ?  348  LYS A HD2  1 
ATOM   5162  H HD3  . LYS A 1 382 ? 8.987   -3.960  35.100 1.00 42.75 ?  348  LYS A HD3  1 
ATOM   5163  H HE2  . LYS A 1 382 ? 8.410   -1.624  34.963 1.00 54.20 ?  348  LYS A HE2  1 
ATOM   5164  H HE3  . LYS A 1 382 ? 7.733   -1.787  36.391 1.00 54.20 ?  348  LYS A HE3  1 
ATOM   5165  H HZ1  . LYS A 1 382 ? 9.851   -0.991  36.606 1.00 56.28 ?  348  LYS A HZ1  1 
ATOM   5166  H HZ2  . LYS A 1 382 ? 9.791   -2.297  37.230 1.00 56.28 ?  348  LYS A HZ2  1 
ATOM   5167  H HZ3  . LYS A 1 382 ? 10.408  -2.144  35.928 1.00 56.28 ?  348  LYS A HZ3  1 
ATOM   5168  N N    . LYS A 1 383 ? 4.216   -7.403  35.128 1.00 16.12 ?  349  LYS A N    1 
ATOM   5169  C CA   . LYS A 1 383 ? 3.999   -8.775  35.571 1.00 16.94 ?  349  LYS A CA   1 
ATOM   5170  C C    . LYS A 1 383 ? 3.107   -9.500  34.577 1.00 19.16 ?  349  LYS A C    1 
ATOM   5171  O O    . LYS A 1 383 ? 2.251   -8.916  33.911 1.00 18.34 ?  349  LYS A O    1 
ATOM   5172  C CB   . LYS A 1 383 ? 3.364   -8.757  36.944 1.00 19.04 ?  349  LYS A CB   1 
ATOM   5173  C CG   . LYS A 1 383 ? 4.374   -8.377  38.033 1.00 20.89 ?  349  LYS A CG   1 
ATOM   5174  C CD   . LYS A 1 383 ? 3.748   -8.186  39.376 1.00 21.69 ?  349  LYS A CD   1 
ATOM   5175  C CE   . LYS A 1 383 ? 4.814   -7.803  40.425 1.00 25.88 ?  349  LYS A CE   1 
ATOM   5176  N NZ   . LYS A 1 383 ? 4.237   -7.776  41.813 1.00 29.70 ?  349  LYS A NZ   1 
ATOM   5177  H H    . LYS A 1 383 ? 3.757   -6.824  35.568 1.00 19.35 ?  349  LYS A H    1 
ATOM   5178  H HA   . LYS A 1 383 ? 4.837   -9.261  35.630 1.00 20.32 ?  349  LYS A HA   1 
ATOM   5179  H HB2  . LYS A 1 383 ? 2.645   -8.106  36.954 1.00 22.84 ?  349  LYS A HB2  1 
ATOM   5180  H HB3  . LYS A 1 383 ? 3.016   -9.640  37.146 1.00 22.84 ?  349  LYS A HB3  1 
ATOM   5181  H HG2  . LYS A 1 383 ? 5.034   -9.084  38.110 1.00 25.07 ?  349  LYS A HG2  1 
ATOM   5182  H HG3  . LYS A 1 383 ? 4.806   -7.545  37.785 1.00 25.07 ?  349  LYS A HG3  1 
ATOM   5183  H HD2  . LYS A 1 383 ? 3.091   -7.474  39.330 1.00 26.03 ?  349  LYS A HD2  1 
ATOM   5184  H HD3  . LYS A 1 383 ? 3.323   -9.012  39.657 1.00 26.03 ?  349  LYS A HD3  1 
ATOM   5185  H HE2  . LYS A 1 383 ? 5.532   -8.455  40.406 1.00 31.05 ?  349  LYS A HE2  1 
ATOM   5186  H HE3  . LYS A 1 383 ? 5.161   -6.920  40.221 1.00 31.05 ?  349  LYS A HE3  1 
ATOM   5187  H HZ1  . LYS A 1 383 ? 4.862   -7.530  42.397 1.00 35.64 ?  349  LYS A HZ1  1 
ATOM   5188  H HZ2  . LYS A 1 383 ? 3.562   -7.197  41.851 1.00 35.64 ?  349  LYS A HZ2  1 
ATOM   5189  H HZ3  . LYS A 1 383 ? 3.937   -8.584  42.034 1.00 35.64 ?  349  LYS A HZ3  1 
ATOM   5190  N N    . ALA A 1 384 ? 3.327   -10.804 34.463 1.00 17.46 ?  350  ALA A N    1 
ATOM   5191  C CA   . ALA A 1 384 ? 2.523   -11.638 33.578 1.00 16.80 ?  350  ALA A CA   1 
ATOM   5192  C C    . ALA A 1 384 ? 1.070   -11.629 33.996 1.00 14.97 ?  350  ALA A C    1 
ATOM   5193  O O    . ALA A 1 384 ? 0.721   -11.844 35.159 1.00 16.93 ?  350  ALA A O    1 
ATOM   5194  C CB   . ALA A 1 384 ? 3.060   -13.085 33.558 1.00 18.43 ?  350  ALA A CB   1 
ATOM   5195  H H    . ALA A 1 384 ? 3.939   -11.233 34.889 1.00 20.96 ?  350  ALA A H    1 
ATOM   5196  H HA   . ALA A 1 384 ? 2.584   -11.280 32.679 1.00 20.16 ?  350  ALA A HA   1 
ATOM   5197  H HB1  . ALA A 1 384 ? 2.505   -13.620 32.969 1.00 22.12 ?  350  ALA A HB1  1 
ATOM   5198  H HB2  . ALA A 1 384 ? 3.974   -13.079 33.235 1.00 22.12 ?  350  ALA A HB2  1 
ATOM   5199  H HB3  . ALA A 1 384 ? 3.029   -13.446 34.458 1.00 22.12 ?  350  ALA A HB3  1 
ATOM   5200  N N    . LEU A 1 385 ? 0.194   -11.347 33.022 1.00 15.92 ?  351  LEU A N    1 
ATOM   5201  C CA   . LEU A 1 385 ? -1.225  -11.262 33.220 1.00 15.68 ?  351  LEU A CA   1 
ATOM   5202  C C    . LEU A 1 385 ? -1.896  -12.493 32.626 1.00 16.37 ?  351  LEU A C    1 
ATOM   5203  O O    . LEU A 1 385 ? -2.440  -13.307 33.380 1.00 18.58 ?  351  LEU A O    1 
ATOM   5204  C CB   . LEU A 1 385 ? -1.735  -9.974  32.542 1.00 16.15 ?  351  LEU A CB   1 
ATOM   5205  C CG   . LEU A 1 385 ? -3.251  -9.797  32.466 1.00 13.31 ?  351  LEU A CG   1 
ATOM   5206  C CD1  . LEU A 1 385 ? -3.855  -9.797  33.840 1.00 14.92 ?  351  LEU A CD1  1 
ATOM   5207  C CD2  . LEU A 1 385 ? -3.575  -8.451  31.736 1.00 14.13 ?  351  LEU A CD2  1 
ATOM   5208  H H    . LEU A 1 385 ? 0.425   -11.197 32.208 1.00 19.11 ?  351  LEU A H    1 
ATOM   5209  H HA   . LEU A 1 385 ? -1.452  -11.214 34.161 1.00 18.82 ?  351  LEU A HA   1 
ATOM   5210  H HB2  . LEU A 1 385 ? -1.383  -9.216  33.035 1.00 19.38 ?  351  LEU A HB2  1 
ATOM   5211  H HB3  . LEU A 1 385 ? -1.400  -9.961  31.631 1.00 19.38 ?  351  LEU A HB3  1 
ATOM   5212  H HG   . LEU A 1 385 ? -3.640  -10.534 31.971 1.00 15.97 ?  351  LEU A HG   1 
ATOM   5213  H HD11 . LEU A 1 385 ? -4.815  -9.681  33.763 1.00 17.91 ?  351  LEU A HD11 1 
ATOM   5214  H HD12 . LEU A 1 385 ? -3.659  -10.644 34.271 1.00 17.91 ?  351  LEU A HD12 1 
ATOM   5215  H HD13 . LEU A 1 385 ? -3.474  -9.068  34.353 1.00 17.91 ?  351  LEU A HD13 1 
ATOM   5216  H HD21 . LEU A 1 385 ? -4.537  -8.360  31.654 1.00 16.96 ?  351  LEU A HD21 1 
ATOM   5217  H HD22 . LEU A 1 385 ? -3.216  -7.715  32.256 1.00 16.96 ?  351  LEU A HD22 1 
ATOM   5218  H HD23 . LEU A 1 385 ? -3.168  -8.463  30.855 1.00 16.96 ?  351  LEU A HD23 1 
ATOM   5219  N N    . GLY A 1 386 ? -1.793  -12.665 31.322 1.00 15.91 ?  352  GLY A N    1 
ATOM   5220  C CA   . GLY A 1 386 ? -2.405  -13.781 30.628 1.00 16.94 ?  352  GLY A CA   1 
ATOM   5221  C C    . GLY A 1 386 ? -3.880  -13.556 30.366 1.00 15.77 ?  352  GLY A C    1 
ATOM   5222  O O    . GLY A 1 386 ? -4.536  -12.702 30.958 1.00 16.42 ?  352  GLY A O    1 
ATOM   5223  H H    . GLY A 1 386 ? -1.361  -12.135 30.801 1.00 19.09 ?  352  GLY A H    1 
ATOM   5224  H HA2  . GLY A 1 386 ? -1.960  -13.914 29.777 1.00 20.33 ?  352  GLY A HA2  1 
ATOM   5225  H HA3  . GLY A 1 386 ? -2.309  -14.584 31.164 1.00 20.33 ?  352  GLY A HA3  1 
ATOM   5226  N N    . ALA A 1 387 ? -4.416  -14.369 29.461 1.00 15.34 ?  353  ALA A N    1 
ATOM   5227  C CA   . ALA A 1 387 ? -5.780  -14.209 29.034 1.00 14.23 ?  353  ALA A CA   1 
ATOM   5228  C C    . ALA A 1 387 ? -6.756  -14.605 30.149 1.00 15.83 ?  353  ALA A C    1 
ATOM   5229  O O    . ALA A 1 387 ? -6.430  -15.429 31.015 1.00 15.71 ?  353  ALA A O    1 
ATOM   5230  C CB   . ALA A 1 387 ? -5.993  -15.065 27.794 1.00 17.07 ?  353  ALA A CB   1 
ATOM   5231  H H    . ALA A 1 387 ? -4.001  -15.021 29.084 1.00 18.41 ?  353  ALA A H    1 
ATOM   5232  H HA   . ALA A 1 387 ? -5.972  -13.283 28.820 1.00 17.08 ?  353  ALA A HA   1 
ATOM   5233  H HB1  . ALA A 1 387 ? -6.874  -14.882 27.431 1.00 20.48 ?  353  ALA A HB1  1 
ATOM   5234  H HB2  . ALA A 1 387 ? -5.313  -14.845 27.138 1.00 20.48 ?  353  ALA A HB2  1 
ATOM   5235  H HB3  . ALA A 1 387 ? -5.925  -16.000 28.041 1.00 20.48 ?  353  ALA A HB3  1 
ATOM   5236  N N    . PRO A 1 388 ? -7.961  -14.034 30.162 1.00 14.43 ?  354  PRO A N    1 
ATOM   5237  C CA   . PRO A 1 388 ? -8.938  -14.420 31.176 1.00 16.53 ?  354  PRO A CA   1 
ATOM   5238  C C    . PRO A 1 388 ? -9.284  -15.899 31.066 1.00 18.06 ?  354  PRO A C    1 
ATOM   5239  O O    . PRO A 1 388 ? -9.299  -16.471 29.972 1.00 19.28 ?  354  PRO A O    1 
ATOM   5240  C CB   . PRO A 1 388 ? -10.158 -13.548 30.877 1.00 18.02 ?  354  PRO A CB   1 
ATOM   5241  C CG   . PRO A 1 388 ? -9.869  -12.889 29.524 1.00 24.71 ?  354  PRO A CG   1 
ATOM   5242  C CD   . PRO A 1 388 ? -8.409  -12.916 29.309 1.00 15.91 ?  354  PRO A CD   1 
ATOM   5243  H HA   . PRO A 1 388 ? -8.604  -14.214 32.063 1.00 19.84 ?  354  PRO A HA   1 
ATOM   5244  H HB2  . PRO A 1 388 ? -10.953 -14.101 30.828 1.00 21.63 ?  354  PRO A HB2  1 
ATOM   5245  H HB3  . PRO A 1 388 ? -10.261 -12.879 31.571 1.00 21.63 ?  354  PRO A HB3  1 
ATOM   5246  H HG2  . PRO A 1 388 ? -10.320 -13.386 28.824 1.00 29.65 ?  354  PRO A HG2  1 
ATOM   5247  H HG3  . PRO A 1 388 ? -10.189 -11.974 29.540 1.00 29.65 ?  354  PRO A HG3  1 
ATOM   5248  H HD2  . PRO A 1 388 ? -8.200  -13.087 28.378 1.00 19.09 ?  354  PRO A HD2  1 
ATOM   5249  H HD3  . PRO A 1 388 ? -8.003  -12.081 29.592 1.00 19.09 ?  354  PRO A HD3  1 
ATOM   5250  N N    . LEU A 1 389 ? -9.564  -16.511 32.213 1.00 17.33 ?  355  LEU A N    1 
ATOM   5251  C CA   . LEU A 1 389 ? -10.074 -17.887 32.250 1.00 18.48 ?  355  LEU A CA   1 
ATOM   5252  C C    . LEU A 1 389 ? -11.574 -17.921 32.414 1.00 24.63 ?  355  LEU A C    1 
ATOM   5253  O O    . LEU A 1 389 ? -12.185 -19.010 32.346 1.00 21.06 ?  355  LEU A O    1 
ATOM   5254  C CB   . LEU A 1 389 ? -9.425  -18.639 33.387 1.00 18.48 ?  355  LEU A CB   1 
ATOM   5255  C CG   . LEU A 1 389 ? -7.945  -18.881 33.202 1.00 21.68 ?  355  LEU A CG   1 
ATOM   5256  C CD1  . LEU A 1 389 ? -7.300  -19.395 34.489 1.00 26.02 ?  355  LEU A CD1  1 
ATOM   5257  C CD2  . LEU A 1 389 ? -7.741  -19.892 32.081 1.00 24.99 ?  355  LEU A CD2  1 
ATOM   5258  H H    . LEU A 1 389 ? -9.467  -16.152 32.988 1.00 20.80 ?  355  LEU A H    1 
ATOM   5259  H HA   . LEU A 1 389 ? -9.846  -18.347 31.427 1.00 22.17 ?  355  LEU A HA   1 
ATOM   5260  H HB2  . LEU A 1 389 ? -9.541  -18.128 34.203 1.00 22.18 ?  355  LEU A HB2  1 
ATOM   5261  H HB3  . LEU A 1 389 ? -9.857  -19.503 33.474 1.00 22.18 ?  355  LEU A HB3  1 
ATOM   5262  H HG   . LEU A 1 389 ? -7.513  -18.044 32.972 1.00 26.01 ?  355  LEU A HG   1 
ATOM   5263  H HD11 . LEU A 1 389 ? -6.354  -19.542 34.331 1.00 31.23 ?  355  LEU A HD11 1 
ATOM   5264  H HD12 . LEU A 1 389 ? -7.419  -18.733 35.188 1.00 31.23 ?  355  LEU A HD12 1 
ATOM   5265  H HD13 . LEU A 1 389 ? -7.726  -20.227 34.746 1.00 31.23 ?  355  LEU A HD13 1 
ATOM   5266  H HD21 . LEU A 1 389 ? -6.824  -20.208 32.104 1.00 29.99 ?  355  LEU A HD21 1 
ATOM   5267  H HD22 . LEU A 1 389 ? -8.350  -20.635 32.210 1.00 29.99 ?  355  LEU A HD22 1 
ATOM   5268  H HD23 . LEU A 1 389 ? -7.920  -19.461 31.230 1.00 29.99 ?  355  LEU A HD23 1 
ATOM   5269  N N    . GLY A 1 390 ? -12.179 -16.776 32.649 1.00 26.35 ?  356  GLY A N    1 
ATOM   5270  C CA   . GLY A 1 390 ? -13.596 -16.587 32.416 1.00 25.53 ?  356  GLY A CA   1 
ATOM   5271  C C    . GLY A 1 390 ? -13.993 -15.167 32.764 1.00 23.95 ?  356  GLY A C    1 
ATOM   5272  O O    . GLY A 1 390 ? -13.159 -14.333 33.115 1.00 24.93 ?  356  GLY A O    1 
ATOM   5273  H H    . GLY A 1 390 ? -11.784 -16.074 32.951 1.00 31.62 ?  356  GLY A H    1 
ATOM   5274  H HA2  . GLY A 1 390 ? -13.803 -16.754 31.483 1.00 30.64 ?  356  GLY A HA2  1 
ATOM   5275  H HA3  . GLY A 1 390 ? -14.106 -17.201 32.967 1.00 30.64 ?  356  GLY A HA3  1 
ATOM   5276  N N    . LYS A 1 391 ? -15.282 -14.926 32.707 1.00 19.04 ?  357  LYS A N    1 
ATOM   5277  C CA   . LYS A 1 391 ? -15.836 -13.643 33.083 1.00 18.19 ?  357  LYS A CA   1 
ATOM   5278  C C    . LYS A 1 391 ? -15.726 -13.413 34.581 1.00 20.38 ?  357  LYS A C    1 
ATOM   5279  O O    . LYS A 1 391 ? -15.580 -14.339 35.379 1.00 20.54 ?  357  LYS A O    1 
ATOM   5280  C CB   . LYS A 1 391 ? -17.289 -13.581 32.651 1.00 19.05 ?  357  LYS A CB   1 
ATOM   5281  C CG   . LYS A 1 391 ? -17.507 -13.769 31.165 1.00 23.38 ?  357  LYS A CG   1 
ATOM   5282  C CD   . LYS A 1 391 ? -16.858 -12.659 30.322 1.00 30.22 ?  357  LYS A CD   1 
ATOM   5283  C CE   . LYS A 1 391 ? -16.692 -13.078 28.842 1.00 42.27 ?  357  LYS A CE   1 
ATOM   5284  N NZ   . LYS A 1 391 ? -17.884 -13.788 28.286 1.00 33.93 ?  357  LYS A NZ   1 
ATOM   5285  H H    . LYS A 1 391 ? -15.871 -15.498 32.450 1.00 22.85 ?  357  LYS A H    1 
ATOM   5286  H HA   . LYS A 1 391 ? -15.343 -12.931 32.646 1.00 21.83 ?  357  LYS A HA   1 
ATOM   5287  H HB2  . LYS A 1 391 ? -17.779 -14.280 33.110 1.00 22.86 ?  357  LYS A HB2  1 
ATOM   5288  H HB3  . LYS A 1 391 ? -17.647 -12.712 32.892 1.00 22.86 ?  357  LYS A HB3  1 
ATOM   5289  H HG2  . LYS A 1 391 ? -17.120 -14.616 30.893 1.00 28.06 ?  357  LYS A HG2  1 
ATOM   5290  H HG3  . LYS A 1 391 ? -18.460 -13.765 30.982 1.00 28.06 ?  357  LYS A HG3  1 
ATOM   5291  H HD2  . LYS A 1 391 ? -17.417 -11.867 30.352 1.00 36.26 ?  357  LYS A HD2  1 
ATOM   5292  H HD3  . LYS A 1 391 ? -15.979 -12.458 30.681 1.00 36.26 ?  357  LYS A HD3  1 
ATOM   5293  H HE2  . LYS A 1 391 ? -16.543 -12.284 28.306 1.00 50.72 ?  357  LYS A HE2  1 
ATOM   5294  H HE3  . LYS A 1 391 ? -15.931 -13.675 28.769 1.00 50.72 ?  357  LYS A HE3  1 
ATOM   5295  H HZ1  . LYS A 1 391 ? -18.000 -14.564 28.706 1.00 40.72 ?  357  LYS A HZ1  1 
ATOM   5296  H HZ2  . LYS A 1 391 ? -18.613 -13.289 28.394 1.00 40.72 ?  357  LYS A HZ2  1 
ATOM   5297  H HZ3  . LYS A 1 391 ? -17.767 -13.944 27.417 1.00 40.72 ?  357  LYS A HZ3  1 
ATOM   5298  N N    . ALA A 1 392 ? -15.815 -12.150 34.974 1.00 17.39 ?  358  ALA A N    1 
ATOM   5299  C CA   . ALA A 1 392 ? -15.887 -11.834 36.387 1.00 16.81 ?  358  ALA A CA   1 
ATOM   5300  C C    . ALA A 1 392 ? -17.129 -12.461 37.008 1.00 18.61 ?  358  ALA A C    1 
ATOM   5301  O O    . ALA A 1 392 ? -18.167 -12.602 36.365 1.00 20.90 ?  358  ALA A O    1 
ATOM   5302  C CB   . ALA A 1 392 ? -15.921 -10.327 36.568 1.00 18.13 ?  358  ALA A CB   1 
ATOM   5303  H H    . ALA A 1 392 ? -15.834 -11.470 34.448 1.00 20.87 ?  358  ALA A H    1 
ATOM   5304  H HA   . ALA A 1 392 ? -15.108 -12.185 36.846 1.00 20.17 ?  358  ALA A HA   1 
ATOM   5305  H HB1  . ALA A 1 392 ? -16.002 -10.125 37.513 1.00 21.76 ?  358  ALA A HB1  1 
ATOM   5306  H HB2  . ALA A 1 392 ? -15.101 -9.948  36.217 1.00 21.76 ?  358  ALA A HB2  1 
ATOM   5307  H HB3  . ALA A 1 392 ? -16.684 -9.969  36.087 1.00 21.76 ?  358  ALA A HB3  1 
ATOM   5308  N N    . ILE A 1 393 ? -17.007 -12.841 38.279 1.00 20.60 ?  359  ILE A N    1 
ATOM   5309  C CA   . ILE A 1 393 ? -18.130 -13.299 39.086 1.00 20.72 ?  359  ILE A CA   1 
ATOM   5310  C C    . ILE A 1 393 ? -18.488 -12.188 40.064 1.00 17.85 ?  359  ILE A C    1 
ATOM   5311  O O    . ILE A 1 393 ? -17.615 -11.737 40.815 1.00 21.25 ?  359  ILE A O    1 
ATOM   5312  C CB   . ILE A 1 393 ? -17.757 -14.581 39.848 1.00 24.67 ?  359  ILE A CB   1 
ATOM   5313  C CG1  . ILE A 1 393 ? -17.385 -15.681 38.858 1.00 25.58 ?  359  ILE A CG1  1 
ATOM   5314  C CG2  . ILE A 1 393 ? -18.902 -15.020 40.758 1.00 26.61 ?  359  ILE A CG2  1 
ATOM   5315  C CD1  . ILE A 1 393 ? -16.766 -16.904 39.506 1.00 29.05 ?  359  ILE A CD1  1 
ATOM   5316  H H    . ILE A 1 393 ? -16.260 -12.842 38.705 1.00 24.72 ?  359  ILE A H    1 
ATOM   5317  H HA   . ILE A 1 393 ? -18.898 -13.474 38.520 1.00 24.86 ?  359  ILE A HA   1 
ATOM   5318  H HB   . ILE A 1 393 ? -16.987 -14.400 40.409 1.00 29.60 ?  359  ILE A HB   1 
ATOM   5319  H HG12 . ILE A 1 393 ? -18.187 -15.966 38.394 1.00 30.69 ?  359  ILE A HG12 1 
ATOM   5320  H HG13 . ILE A 1 393 ? -16.743 -15.325 38.224 1.00 30.69 ?  359  ILE A HG13 1 
ATOM   5321  H HG21 . ILE A 1 393 ? -18.744 -15.932 41.047 1.00 31.93 ?  359  ILE A HG21 1 
ATOM   5322  H HG22 . ILE A 1 393 ? -18.937 -14.431 41.528 1.00 31.93 ?  359  ILE A HG22 1 
ATOM   5323  H HG23 . ILE A 1 393 ? -19.735 -14.969 40.264 1.00 31.93 ?  359  ILE A HG23 1 
ATOM   5324  H HD11 . ILE A 1 393 ? -16.438 -17.497 38.813 1.00 34.86 ?  359  ILE A HD11 1 
ATOM   5325  H HD12 . ILE A 1 393 ? -16.033 -16.622 40.075 1.00 34.86 ?  359  ILE A HD12 1 
ATOM   5326  H HD13 . ILE A 1 393 ? -17.441 -17.356 40.036 1.00 34.86 ?  359  ILE A HD13 1 
ATOM   5327  N N    . LYS A 1 394 ? -19.755 -11.796 40.076 1.00 19.18 ?  360  LYS A N    1 
ATOM   5328  C CA   . LYS A 1 394 ? -20.265 -10.730 40.931 1.00 19.74 ?  360  LYS A CA   1 
ATOM   5329  C C    . LYS A 1 394 ? -21.075 -11.348 42.067 1.00 25.27 ?  360  LYS A C    1 
ATOM   5330  O O    . LYS A 1 394 ? -21.987 -12.152 41.822 1.00 25.16 ?  360  LYS A O    1 
ATOM   5331  C CB   . LYS A 1 394 ? -21.139 -9.763  40.131 1.00 19.81 ?  360  LYS A CB   1 
ATOM   5332  C CG   . LYS A 1 394 ? -21.702 -8.579  40.966 1.00 19.85 ?  360  LYS A CG   1 
ATOM   5333  C CD   . LYS A 1 394 ? -22.563 -7.665  40.107 1.00 24.89 ?  360  LYS A CD   1 
ATOM   5334  C CE   . LYS A 1 394 ? -23.057 -6.445  40.866 1.00 27.68 ?  360  LYS A CE   1 
ATOM   5335  N NZ   . LYS A 1 394 ? -23.957 -6.827  41.982 1.00 27.51 ?  360  LYS A NZ   1 
ATOM   5336  H H    . LYS A 1 394 ? -20.363 -12.145 39.578 1.00 23.01 ?  360  LYS A H    1 
ATOM   5337  H HA   . LYS A 1 394 ? -19.524 -10.232 41.311 1.00 23.69 ?  360  LYS A HA   1 
ATOM   5338  H HB2  . LYS A 1 394 ? -20.609 -9.389  39.410 1.00 23.77 ?  360  LYS A HB2  1 
ATOM   5339  H HB3  . LYS A 1 394 ? -21.894 -10.253 39.769 1.00 23.77 ?  360  LYS A HB3  1 
ATOM   5340  H HG2  . LYS A 1 394 ? -22.248 -8.925  41.689 1.00 23.83 ?  360  LYS A HG2  1 
ATOM   5341  H HG3  . LYS A 1 394 ? -20.966 -8.059  41.325 1.00 23.83 ?  360  LYS A HG3  1 
ATOM   5342  H HD2  . LYS A 1 394 ? -22.041 -7.356  39.350 1.00 29.87 ?  360  LYS A HD2  1 
ATOM   5343  H HD3  . LYS A 1 394 ? -23.338 -8.159  39.796 1.00 29.87 ?  360  LYS A HD3  1 
ATOM   5344  H HE2  . LYS A 1 394 ? -22.298 -5.968  41.236 1.00 33.22 ?  360  LYS A HE2  1 
ATOM   5345  H HE3  . LYS A 1 394 ? -23.549 -5.868  40.261 1.00 33.22 ?  360  LYS A HE3  1 
ATOM   5346  H HZ1  . LYS A 1 394 ? -24.649 -7.292  41.670 1.00 33.01 ?  360  LYS A HZ1  1 
ATOM   5347  H HZ2  . LYS A 1 394 ? -23.516 -7.328  42.571 1.00 33.01 ?  360  LYS A HZ2  1 
ATOM   5348  H HZ3  . LYS A 1 394 ? -24.260 -6.098  42.392 1.00 33.01 ?  360  LYS A HZ3  1 
ATOM   5349  N N    . ASN A 1 395 ? -20.733 -10.965 43.294 1.00 22.28 ?  361  ASN A N    1 
ATOM   5350  C CA   . ASN A 1 395 ? -21.476 -11.337 44.507 1.00 28.11 ?  361  ASN A CA   1 
ATOM   5351  C C    . ASN A 1 395 ? -21.662 -10.077 45.343 1.00 20.13 ?  361  ASN A C    1 
ATOM   5352  O O    . ASN A 1 395 ? -20.782 -9.717  46.125 1.00 23.08 ?  361  ASN A O    1 
ATOM   5353  C CB   . ASN A 1 395 ? -20.734 -12.390 45.281 1.00 26.66 ?  361  ASN A CB   1 
ATOM   5354  C CG   . ASN A 1 395 ? -21.469 -12.786 46.538 1.00 42.04 ?  361  ASN A CG   1 
ATOM   5355  O OD1  . ASN A 1 395 ? -22.701 -12.758 46.576 1.00 39.36 ?  361  ASN A OD1  1 
ATOM   5356  N ND2  . ASN A 1 395 ? -20.723 -13.158 47.571 1.00 46.53 ?  361  ASN A ND2  1 
ATOM   5357  H H    . ASN A 1 395 ? -20.048 -10.471 43.461 1.00 26.74 ?  361  ASN A H    1 
ATOM   5358  H HA   . ASN A 1 395 ? -22.349 -11.678 44.255 1.00 33.73 ?  361  ASN A HA   1 
ATOM   5359  H HB2  . ASN A 1 395 ? -20.631 -13.181 44.727 1.00 32.00 ?  361  ASN A HB2  1 
ATOM   5360  H HB3  . ASN A 1 395 ? -19.862 -12.047 45.533 1.00 32.00 ?  361  ASN A HB3  1 
ATOM   5361  H HD21 . ASN A 1 395 ? -19.866 -13.165 47.503 1.00 55.83 ?  361  ASN A HD21 1 
ATOM   5362  H HD22 . ASN A 1 395 ? -21.097 -13.392 48.310 1.00 55.83 ?  361  ASN A HD22 1 
ATOM   5363  N N    . GLY A 1 396 ? -22.792 -9.428  45.169 1.00 23.86 ?  362  GLY A N    1 
ATOM   5364  C CA   . GLY A 1 396 ? -22.989 -8.132  45.791 1.00 26.10 ?  362  GLY A CA   1 
ATOM   5365  C C    . GLY A 1 396 ? -22.011 -7.125  45.218 1.00 23.80 ?  362  GLY A C    1 
ATOM   5366  O O    . GLY A 1 396 ? -21.951 -6.937  43.996 1.00 24.21 ?  362  GLY A O    1 
ATOM   5367  H H    . GLY A 1 396 ? -23.457 -9.709  44.701 1.00 28.63 ?  362  GLY A H    1 
ATOM   5368  H HA2  . GLY A 1 396 ? -23.893 -7.821  45.627 1.00 31.33 ?  362  GLY A HA2  1 
ATOM   5369  H HA3  . GLY A 1 396 ? -22.847 -8.199  46.748 1.00 31.33 ?  362  GLY A HA3  1 
ATOM   5370  N N    . TYR A 1 397 ? -21.221 -6.491  46.078 1.00 22.34 ?  363  TYR A N    1 
ATOM   5371  C CA   . TYR A 1 397 ? -20.219 -5.522  45.644 1.00 21.42 ?  363  TYR A CA   1 
ATOM   5372  C C    . TYR A 1 397 ? -18.837 -6.146  45.534 1.00 23.98 ?  363  TYR A C    1 
ATOM   5373  O O    . TYR A 1 397 ? -17.837 -5.432  45.379 1.00 22.49 ?  363  TYR A O    1 
ATOM   5374  C CB   . TYR A 1 397 ? -20.199 -4.309  46.583 1.00 24.26 ?  363  TYR A CB   1 
ATOM   5375  C CG   . TYR A 1 397 ? -21.499 -3.534  46.575 1.00 23.30 ?  363  TYR A CG   1 
ATOM   5376  C CD1  . TYR A 1 397 ? -22.051 -3.083  45.393 1.00 27.10 ?  363  TYR A CD1  1 
ATOM   5377  C CD2  . TYR A 1 397 ? -22.174 -3.251  47.763 1.00 29.37 ?  363  TYR A CD2  1 
ATOM   5378  C CE1  . TYR A 1 397 ? -23.243 -2.391  45.383 1.00 29.00 ?  363  TYR A CE1  1 
ATOM   5379  C CE2  . TYR A 1 397 ? -23.366 -2.553  47.757 1.00 30.83 ?  363  TYR A CE2  1 
ATOM   5380  C CZ   . TYR A 1 397 ? -23.893 -2.126  46.569 1.00 34.87 ?  363  TYR A CZ   1 
ATOM   5381  O OH   . TYR A 1 397 ? -25.084 -1.439  46.568 1.00 37.67 ?  363  TYR A OH   1 
ATOM   5382  H H    . TYR A 1 397 ? -21.247 -6.606  46.930 1.00 26.81 ?  363  TYR A H    1 
ATOM   5383  H HA   . TYR A 1 397 ? -20.464 -5.188  44.767 1.00 25.71 ?  363  TYR A HA   1 
ATOM   5384  H HB2  . TYR A 1 397 ? -20.038 -4.615  47.490 1.00 29.11 ?  363  TYR A HB2  1 
ATOM   5385  H HB3  . TYR A 1 397 ? -19.490 -3.708  46.306 1.00 29.11 ?  363  TYR A HB3  1 
ATOM   5386  H HD1  . TYR A 1 397 ? -21.612 -3.250  44.590 1.00 32.51 ?  363  TYR A HD1  1 
ATOM   5387  H HD2  . TYR A 1 397 ? -21.815 -3.536  48.572 1.00 35.25 ?  363  TYR A HD2  1 
ATOM   5388  H HE1  . TYR A 1 397 ? -23.607 -2.102  44.577 1.00 34.80 ?  363  TYR A HE1  1 
ATOM   5389  H HE2  . TYR A 1 397 ? -23.808 -2.374  48.556 1.00 37.00 ?  363  TYR A HE2  1 
ATOM   5390  H HH   . TYR A 1 397 ? -25.362 -1.345  47.355 1.00 45.20 ?  363  TYR A HH   1 
ATOM   5391  N N    . ILE A 1 398 ? -18.748 -7.466  45.645 1.00 22.38 ?  364  ILE A N    1 
ATOM   5392  C CA   . ILE A 1 398 ? -17.490 -8.176  45.556 1.00 22.16 ?  364  ILE A CA   1 
ATOM   5393  C C    . ILE A 1 398 ? -17.433 -8.853  44.200 1.00 23.42 ?  364  ILE A C    1 
ATOM   5394  O O    . ILE A 1 398 ? -18.370 -9.567  43.809 1.00 23.62 ?  364  ILE A O    1 
ATOM   5395  C CB   . ILE A 1 398 ? -17.328 -9.200  46.702 1.00 22.45 ?  364  ILE A CB   1 
ATOM   5396  C CG1  . ILE A 1 398 ? -17.154 -8.444  48.025 1.00 26.53 ?  364  ILE A CG1  1 
ATOM   5397  C CG2  . ILE A 1 398 ? -16.112 -10.116 46.449 1.00 23.60 ?  364  ILE A CG2  1 
ATOM   5398  C CD1  . ILE A 1 398 ? -17.277 -9.328  49.261 1.00 33.04 ?  364  ILE A CD1  1 
ATOM   5399  H H    . ILE A 1 398 ? -19.424 -7.982  45.777 1.00 26.86 ?  364  ILE A H    1 
ATOM   5400  H HA   . ILE A 1 398 ? -16.757 -7.545  45.621 1.00 26.59 ?  364  ILE A HA   1 
ATOM   5401  H HB   . ILE A 1 398 ? -18.122 -9.756  46.743 1.00 26.94 ?  364  ILE A HB   1 
ATOM   5402  H HG12 . ILE A 1 398 ? -16.272 -8.039  48.038 1.00 31.83 ?  364  ILE A HG12 1 
ATOM   5403  H HG13 . ILE A 1 398 ? -17.836 -7.757  48.084 1.00 31.83 ?  364  ILE A HG13 1 
ATOM   5404  H HG21 . ILE A 1 398 ? -15.923 -10.621 47.256 1.00 28.32 ?  364  ILE A HG21 1 
ATOM   5405  H HG22 . ILE A 1 398 ? -16.319 -10.723 45.721 1.00 28.32 ?  364  ILE A HG22 1 
ATOM   5406  H HG23 . ILE A 1 398 ? -15.346 -9.568  46.216 1.00 28.32 ?  364  ILE A HG23 1 
ATOM   5407  H HD11 . ILE A 1 398 ? -17.301 -8.765  50.051 1.00 39.65 ?  364  ILE A HD11 1 
ATOM   5408  H HD12 . ILE A 1 398 ? -18.095 -9.846  49.199 1.00 39.65 ?  364  ILE A HD12 1 
ATOM   5409  H HD13 . ILE A 1 398 ? -16.512 -9.923  49.302 1.00 39.65 ?  364  ILE A HD13 1 
ATOM   5410  N N    . TYR A 1 399 ? -16.325 -8.649  43.490 1.00 19.55 ?  365  TYR A N    1 
ATOM   5411  C CA   . TYR A 1 399 ? -16.128 -9.260  42.184 1.00 18.97 ?  365  TYR A CA   1 
ATOM   5412  C C    . TYR A 1 399 ? -14.829 -10.040 42.197 1.00 17.70 ?  365  TYR A C    1 
ATOM   5413  O O    . TYR A 1 399 ? -13.849 -9.627  42.821 1.00 20.11 ?  365  TYR A O    1 
ATOM   5414  C CB   . TYR A 1 399 ? -15.999 -8.215  41.046 1.00 18.73 ?  365  TYR A CB   1 
ATOM   5415  C CG   . TYR A 1 399 ? -17.200 -7.374  40.793 1.00 19.90 ?  365  TYR A CG   1 
ATOM   5416  C CD1  . TYR A 1 399 ? -17.536 -6.333  41.661 1.00 20.77 ?  365  TYR A CD1  1 
ATOM   5417  C CD2  . TYR A 1 399 ? -17.985 -7.563  39.658 1.00 17.94 ?  365  TYR A CD2  1 
ATOM   5418  C CE1  . TYR A 1 399 ? -18.617 -5.541  41.407 1.00 23.43 ?  365  TYR A CE1  1 
ATOM   5419  C CE2  . TYR A 1 399 ? -19.079 -6.768  39.400 1.00 20.09 ?  365  TYR A CE2  1 
ATOM   5420  C CZ   . TYR A 1 399 ? -19.391 -5.753  40.285 1.00 20.45 ?  365  TYR A CZ   1 
ATOM   5421  O OH   . TYR A 1 399 ? -20.460 -4.910  40.063 1.00 24.45 ?  365  TYR A OH   1 
ATOM   5422  H H    . TYR A 1 399 ? -15.669 -8.156  43.749 1.00 23.46 ?  365  TYR A H    1 
ATOM   5423  H HA   . TYR A 1 399 ? -16.890 -9.833  42.008 1.00 22.76 ?  365  TYR A HA   1 
ATOM   5424  H HB2  . TYR A 1 399 ? -15.270 -7.615  41.267 1.00 22.47 ?  365  TYR A HB2  1 
ATOM   5425  H HB3  . TYR A 1 399 ? -15.802 -8.688  40.222 1.00 22.47 ?  365  TYR A HB3  1 
ATOM   5426  H HD1  . TYR A 1 399 ? -17.018 -6.178  42.417 1.00 24.92 ?  365  TYR A HD1  1 
ATOM   5427  H HD2  . TYR A 1 399 ? -17.765 -8.241  39.061 1.00 21.53 ?  365  TYR A HD2  1 
ATOM   5428  H HE1  . TYR A 1 399 ? -18.834 -4.854  41.994 1.00 28.12 ?  365  TYR A HE1  1 
ATOM   5429  H HE2  . TYR A 1 399 ? -19.600 -6.911  38.643 1.00 24.11 ?  365  TYR A HE2  1 
ATOM   5430  H HH   . TYR A 1 399 ? -20.821 -5.091  39.326 1.00 29.34 ?  365  TYR A HH   1 
ATOM   5431  N N    . THR A 1 400 ? -14.798 -11.185 41.494 1.00 19.79 ?  366  THR A N    1 
ATOM   5432  C CA   . THR A 1 400 ? -13.563 -11.932 41.310 1.00 19.48 ?  366  THR A CA   1 
ATOM   5433  C C    . THR A 1 400 ? -13.387 -12.279 39.834 1.00 16.41 ?  366  THR A C    1 
ATOM   5434  O O    . THR A 1 400 ? -14.365 -12.379 39.087 1.00 17.67 ?  366  THR A O    1 
ATOM   5435  C CB   . THR A 1 400 ? -13.526 -13.236 42.147 1.00 20.51 ?  366  THR A CB   1 
ATOM   5436  O OG1  . THR A 1 400 ? -14.582 -14.067 41.708 1.00 22.22 ?  366  THR A OG1  1 
ATOM   5437  C CG2  . THR A 1 400 ? -13.691 -12.922 43.639 1.00 21.75 ?  366  THR A CG2  1 
ATOM   5438  H H    . THR A 1 400 ? -15.484 -11.542 41.117 1.00 23.75 ?  366  THR A H    1 
ATOM   5439  H HA   . THR A 1 400 ? -12.821 -11.374 41.594 1.00 23.37 ?  366  THR A HA   1 
ATOM   5440  H HB   . THR A 1 400 ? -12.676 -13.690 42.038 1.00 24.61 ?  366  THR A HB   1 
ATOM   5441  H HG1  . THR A 1 400 ? -14.449 -14.858 41.959 1.00 26.66 ?  366  THR A HG1  1 
ATOM   5442  H HG21 . THR A 1 400 ? -13.649 -13.741 44.156 1.00 26.10 ?  366  THR A HG21 1 
ATOM   5443  H HG22 . THR A 1 400 ? -12.983 -12.327 43.933 1.00 26.10 ?  366  THR A HG22 1 
ATOM   5444  H HG23 . THR A 1 400 ? -14.547 -12.494 43.795 1.00 26.10 ?  366  THR A HG23 1 
ATOM   5445  N N    . ARG A 1 401 ? -12.132 -12.462 39.437 1.00 17.05 ?  367  ARG A N    1 
ATOM   5446  C CA   . ARG A 1 401 ? -11.865 -12.919 38.073 1.00 15.88 ?  367  ARG A CA   1 
ATOM   5447  C C    . ARG A 1 401 ? -10.514 -13.590 38.032 1.00 15.24 ?  367  ARG A C    1 
ATOM   5448  O O    . ARG A 1 401 ? -9.561  -13.174 38.695 1.00 17.52 ?  367  ARG A O    1 
ATOM   5449  C CB   . ARG A 1 401 ? -11.920 -11.762 37.044 1.00 16.06 ?  367  ARG A CB   1 
ATOM   5450  C CG   . ARG A 1 401 ? -12.057 -12.261 35.623 1.00 17.69 ?  367  ARG A CG   1 
ATOM   5451  C CD   . ARG A 1 401 ? -12.291 -11.100 34.665 1.00 16.51 ?  367  ARG A CD   1 
ATOM   5452  N NE   . ARG A 1 401 ? -12.534 -11.579 33.310 1.00 17.72 ?  367  ARG A NE   1 
ATOM   5453  C CZ   . ARG A 1 401 ? -12.668 -10.790 32.254 1.00 15.75 ?  367  ARG A CZ   1 
ATOM   5454  N NH1  . ARG A 1 401 ? -12.460 -9.489  32.328 1.00 15.29 ?  367  ARG A NH1  1 
ATOM   5455  N NH2  . ARG A 1 401 ? -13.020 -11.302 31.092 1.00 15.88 ?  367  ARG A NH2  1 
ATOM   5456  H H    . ARG A 1 401 ? -11.435 -12.332 39.924 1.00 20.46 ?  367  ARG A H    1 
ATOM   5457  H HA   . ARG A 1 401 ? -12.541 -13.569 37.826 1.00 19.05 ?  367  ARG A HA   1 
ATOM   5458  H HB2  . ARG A 1 401 ? -12.685 -11.199 37.241 1.00 19.28 ?  367  ARG A HB2  1 
ATOM   5459  H HB3  . ARG A 1 401 ? -11.102 -11.245 37.105 1.00 19.28 ?  367  ARG A HB3  1 
ATOM   5460  H HG2  . ARG A 1 401 ? -11.242 -12.717 35.360 1.00 21.23 ?  367  ARG A HG2  1 
ATOM   5461  H HG3  . ARG A 1 401 ? -12.811 -12.867 35.563 1.00 21.23 ?  367  ARG A HG3  1 
ATOM   5462  H HD2  . ARG A 1 401 ? -13.066 -10.594 34.955 1.00 19.82 ?  367  ARG A HD2  1 
ATOM   5463  H HD3  . ARG A 1 401 ? -11.508 -10.529 34.652 1.00 19.82 ?  367  ARG A HD3  1 
ATOM   5464  H HE   . ARG A 1 401 ? -12.594 -12.428 33.188 1.00 21.27 ?  367  ARG A HE   1 
ATOM   5465  H HH11 . ARG A 1 401 ? -12.231 -9.132  33.077 1.00 18.35 ?  367  ARG A HH11 1 
ATOM   5466  H HH12 . ARG A 1 401 ? -12.553 -8.997  31.629 1.00 18.35 ?  367  ARG A HH12 1 
ATOM   5467  H HH21 . ARG A 1 401 ? -13.163 -12.147 31.021 1.00 19.05 ?  367  ARG A HH21 1 
ATOM   5468  H HH22 . ARG A 1 401 ? -13.107 -10.792 30.406 1.00 19.05 ?  367  ARG A HH22 1 
ATOM   5469  N N    . LYS A 1 402 ? -10.442 -14.678 37.258 1.00 18.26 ?  368  LYS A N    1 
ATOM   5470  C CA   . LYS A 1 402 ? -9.216  -15.418 37.047 1.00 16.82 ?  368  LYS A CA   1 
ATOM   5471  C C    . LYS A 1 402 ? -8.669  -15.210 35.643 1.00 15.85 ?  368  LYS A C    1 
ATOM   5472  O O    . LYS A 1 402 ? -9.421  -15.270 34.653 1.00 17.33 ?  368  LYS A O    1 
ATOM   5473  C CB   . LYS A 1 402 ? -9.455  -16.917 37.301 1.00 21.50 ?  368  LYS A CB   1 
ATOM   5474  C CG   . LYS A 1 402 ? -9.980  -17.176 38.713 1.00 27.66 ?  368  LYS A CG   1 
ATOM   5475  C CD   . LYS A 1 402 ? -9.959  -18.685 39.039 1.00 34.83 ?  368  LYS A CD   1 
ATOM   5476  C CE   . LYS A 1 402 ? -9.423  -18.953 40.458 1.00 48.05 ?  368  LYS A CE   1 
ATOM   5477  N NZ   . LYS A 1 402 ? -8.051  -19.528 40.449 1.00 47.47 ?  368  LYS A NZ   1 
ATOM   5478  H H    . LYS A 1 402 ? -11.115 -15.007 36.837 1.00 21.92 ?  368  LYS A H    1 
ATOM   5479  H HA   . LYS A 1 402 ? -8.544  -15.082 37.660 1.00 20.19 ?  368  LYS A HA   1 
ATOM   5480  H HB2  . LYS A 1 402 ? -10.110 -17.249 36.667 1.00 25.80 ?  368  LYS A HB2  1 
ATOM   5481  H HB3  . LYS A 1 402 ? -8.618  -17.397 37.195 1.00 25.80 ?  368  LYS A HB3  1 
ATOM   5482  H HG2  . LYS A 1 402 ? -9.420  -16.715 39.357 1.00 33.19 ?  368  LYS A HG2  1 
ATOM   5483  H HG3  . LYS A 1 402 ? -10.894 -16.859 38.781 1.00 33.19 ?  368  LYS A HG3  1 
ATOM   5484  H HD2  . LYS A 1 402 ? -10.861 -19.038 38.983 1.00 41.79 ?  368  LYS A HD2  1 
ATOM   5485  H HD3  . LYS A 1 402 ? -9.384  -19.142 38.406 1.00 41.79 ?  368  LYS A HD3  1 
ATOM   5486  H HE2  . LYS A 1 402 ? -9.396  -18.117 40.950 1.00 57.66 ?  368  LYS A HE2  1 
ATOM   5487  H HE3  . LYS A 1 402 ? -10.010 -19.582 40.906 1.00 57.66 ?  368  LYS A HE3  1 
ATOM   5488  H HZ1  . LYS A 1 402 ? -7.769  -19.657 41.283 1.00 56.96 ?  368  LYS A HZ1  1 
ATOM   5489  H HZ2  . LYS A 1 402 ? -8.051  -20.308 40.020 1.00 56.96 ?  368  LYS A HZ2  1 
ATOM   5490  H HZ3  . LYS A 1 402 ? -7.491  -18.972 40.037 1.00 56.96 ?  368  LYS A HZ3  1 
ATOM   5491  N N    . PHE A 1 403 ? -7.373  -14.974 35.575 1.00 16.05 ?  369  PHE A N    1 
ATOM   5492  C CA   . PHE A 1 403 ? -6.574  -14.886 34.368 1.00 17.24 ?  369  PHE A CA   1 
ATOM   5493  C C    . PHE A 1 403 ? -5.507  -15.974 34.458 1.00 16.88 ?  369  PHE A C    1 
ATOM   5494  O O    . PHE A 1 403 ? -5.242  -16.513 35.539 1.00 18.53 ?  369  PHE A O    1 
ATOM   5495  C CB   . PHE A 1 403 ? -5.910  -13.494 34.222 1.00 15.48 ?  369  PHE A CB   1 
ATOM   5496  C CG   . PHE A 1 403 ? -6.885  -12.369 34.050 1.00 14.84 ?  369  PHE A CG   1 
ATOM   5497  C CD1  . PHE A 1 403 ? -7.593  -11.881 35.137 1.00 15.27 ?  369  PHE A CD1  1 
ATOM   5498  C CD2  . PHE A 1 403 ? -7.065  -11.783 32.807 1.00 15.85 ?  369  PHE A CD2  1 
ATOM   5499  C CE1  . PHE A 1 403 ? -8.465  -10.825 34.995 1.00 15.83 ?  369  PHE A CE1  1 
ATOM   5500  C CE2  . PHE A 1 403 ? -7.960  -10.718 32.662 1.00 16.98 ?  369  PHE A CE2  1 
ATOM   5501  C CZ   . PHE A 1 403 ? -8.657  -10.266 33.745 1.00 15.41 ?  369  PHE A CZ   1 
ATOM   5502  H H    . PHE A 1 403 ? -6.892  -14.850 36.276 1.00 19.26 ?  369  PHE A H    1 
ATOM   5503  H HA   . PHE A 1 403 ? -7.126  -15.020 33.582 1.00 20.69 ?  369  PHE A HA   1 
ATOM   5504  H HB2  . PHE A 1 403 ? -5.388  -13.314 35.019 1.00 18.57 ?  369  PHE A HB2  1 
ATOM   5505  H HB3  . PHE A 1 403 ? -5.333  -13.506 33.443 1.00 18.57 ?  369  PHE A HB3  1 
ATOM   5506  H HD1  . PHE A 1 403 ? -7.478  -12.272 35.973 1.00 18.32 ?  369  PHE A HD1  1 
ATOM   5507  H HD2  . PHE A 1 403 ? -6.592  -12.097 32.071 1.00 19.02 ?  369  PHE A HD2  1 
ATOM   5508  H HE1  . PHE A 1 403 ? -8.921  -10.490 35.734 1.00 19.00 ?  369  PHE A HE1  1 
ATOM   5509  H HE2  . PHE A 1 403 ? -8.079  -10.319 31.831 1.00 20.37 ?  369  PHE A HE2  1 
ATOM   5510  H HZ   . PHE A 1 403 ? -9.269  -9.574  33.640 1.00 18.50 ?  369  PHE A HZ   1 
ATOM   5511  N N    . GLU A 1 404 ? -4.869  -16.270 33.331 1.00 17.61 ?  370  GLU A N    1 
ATOM   5512  C CA   . GLU A 1 404 ? -3.892  -17.366 33.338 1.00 16.63 ?  370  GLU A CA   1 
ATOM   5513  C C    . GLU A 1 404 ? -2.791  -17.157 34.377 1.00 19.05 ?  370  GLU A C    1 
ATOM   5514  O O    . GLU A 1 404 ? -2.330  -18.126 35.004 1.00 20.66 ?  370  GLU A O    1 
ATOM   5515  C CB   . GLU A 1 404 ? -3.311  -17.550 31.949 1.00 16.20 ?  370  GLU A CB   1 
ATOM   5516  C CG   . GLU A 1 404 ? -4.305  -18.189 31.001 1.00 20.16 ?  370  GLU A CG   1 
ATOM   5517  C CD   . GLU A 1 404 ? -3.918  -18.127 29.556 1.00 33.28 ?  370  GLU A CD   1 
ATOM   5518  O OE1  . GLU A 1 404 ? -2.789  -17.690 29.244 1.00 37.74 ?  370  GLU A OE1  1 
ATOM   5519  O OE2  . GLU A 1 404 ? -4.737  -18.582 28.725 1.00 26.33 ?  370  GLU A OE2  1 
ATOM   5520  H H    . GLU A 1 404 ? -4.975  -15.872 32.576 1.00 21.13 ?  370  GLU A H    1 
ATOM   5521  H HA   . GLU A 1 404 ? -4.348  -18.187 33.578 1.00 19.96 ?  370  GLU A HA   1 
ATOM   5522  H HB2  . GLU A 1 404 ? -3.062  -16.684 31.590 1.00 19.44 ?  370  GLU A HB2  1 
ATOM   5523  H HB3  . GLU A 1 404 ? -2.531  -18.123 32.003 1.00 19.44 ?  370  GLU A HB3  1 
ATOM   5524  H HG2  . GLU A 1 404 ? -4.401  -19.124 31.238 1.00 24.19 ?  370  GLU A HG2  1 
ATOM   5525  H HG3  . GLU A 1 404 ? -5.157  -17.734 31.094 1.00 24.19 ?  370  GLU A HG3  1 
ATOM   5526  N N    . ASN A 1 405 ? -2.380  -15.908 34.633 1.00 16.30 ?  371  ASN A N    1 
ATOM   5527  C CA   . ASN A 1 405 ? -1.296  -15.632 35.569 1.00 18.85 ?  371  ASN A CA   1 
ATOM   5528  C C    . ASN A 1 405 ? -1.705  -14.692 36.699 1.00 16.27 ?  371  ASN A C    1 
ATOM   5529  O O    . ASN A 1 405 ? -0.824  -14.137 37.372 1.00 18.80 ?  371  ASN A O    1 
ATOM   5530  C CB   . ASN A 1 405 ? -0.059  -15.130 34.832 1.00 18.62 ?  371  ASN A CB   1 
ATOM   5531  C CG   . ASN A 1 405 ? 0.398   -16.068 33.740 1.00 25.17 ?  371  ASN A CG   1 
ATOM   5532  O OD1  . ASN A 1 405 ? 0.140   -15.846 32.557 1.00 26.69 ?  371  ASN A OD1  1 
ATOM   5533  N ND2  . ASN A 1 405 ? 1.095   -17.118 34.129 1.00 36.30 ?  371  ASN A ND2  1 
ATOM   5534  H H    . ASN A 1 405 ? -2.719  -15.204 34.273 1.00 19.56 ?  371  ASN A H    1 
ATOM   5535  H HA   . ASN A 1 405 ? -1.051  -16.467 35.997 1.00 22.62 ?  371  ASN A HA   1 
ATOM   5536  H HB2  . ASN A 1 405 ? -0.261  -14.273 34.425 1.00 22.35 ?  371  ASN A HB2  1 
ATOM   5537  H HB3  . ASN A 1 405 ? 0.668   -15.034 35.467 1.00 22.35 ?  371  ASN A HB3  1 
ATOM   5538  H HD21 . ASN A 1 405 ? 1.264   -17.236 34.964 1.00 43.56 ?  371  ASN A HD21 1 
ATOM   5539  H HD22 . ASN A 1 405 ? 1.379   -17.684 33.548 1.00 43.56 ?  371  ASN A HD22 1 
ATOM   5540  N N    . LEU A 1 406 ? -2.994  -14.548 36.976 1.00 15.80 ?  372  LEU A N    1 
ATOM   5541  C CA   . LEU A 1 406 ? -3.423  -13.575 37.974 1.00 16.02 ?  372  LEU A CA   1 
ATOM   5542  C C    . LEU A 1 406 ? -4.821  -13.897 38.467 1.00 16.44 ?  372  LEU A C    1 
ATOM   5543  O O    . LEU A 1 406 ? -5.714  -14.203 37.660 1.00 17.94 ?  372  LEU A O    1 
ATOM   5544  C CB   . LEU A 1 406 ? -3.444  -12.151 37.365 1.00 17.17 ?  372  LEU A CB   1 
ATOM   5545  C CG   . LEU A 1 406 ? -4.069  -11.031 38.186 1.00 15.55 ?  372  LEU A CG   1 
ATOM   5546  C CD1  . LEU A 1 406 ? -3.274  -10.729 39.450 1.00 17.84 ?  372  LEU A CD1  1 
ATOM   5547  C CD2  . LEU A 1 406 ? -4.207  -9.779  37.296 1.00 17.77 ?  372  LEU A CD2  1 
ATOM   5548  H H    . LEU A 1 406 ? -3.630  -14.994 36.607 1.00 18.96 ?  372  LEU A H    1 
ATOM   5549  H HA   . LEU A 1 406 ? -2.813  -13.623 38.727 1.00 19.23 ?  372  LEU A HA   1 
ATOM   5550  H HB2  . LEU A 1 406 ? -2.525  -11.891 37.192 1.00 20.60 ?  372  LEU A HB2  1 
ATOM   5551  H HB3  . LEU A 1 406 ? -3.938  -12.194 36.531 1.00 20.60 ?  372  LEU A HB3  1 
ATOM   5552  H HG   . LEU A 1 406 ? -4.947  -11.308 38.489 1.00 18.66 ?  372  LEU A HG   1 
ATOM   5553  H HD11 . LEU A 1 406 ? -3.838  -10.238 40.068 1.00 21.41 ?  372  LEU A HD11 1 
ATOM   5554  H HD12 . LEU A 1 406 ? -2.992  -11.565 39.853 1.00 21.41 ?  372  LEU A HD12 1 
ATOM   5555  H HD13 . LEU A 1 406 ? -2.498  -10.196 39.215 1.00 21.41 ?  372  LEU A HD13 1 
ATOM   5556  H HD21 . LEU A 1 406 ? -4.582  -9.057  37.823 1.00 21.32 ?  372  LEU A HD21 1 
ATOM   5557  H HD22 . LEU A 1 406 ? -3.330  -9.528  36.966 1.00 21.32 ?  372  LEU A HD22 1 
ATOM   5558  H HD23 . LEU A 1 406 ? -4.794  -9.985  36.551 1.00 21.32 ?  372  LEU A HD23 1 
ATOM   5559  N N    . ASP A 1 407 ? -5.047  -13.781 39.780 1.00 17.11 ?  373  ASP A N    1 
ATOM   5560  C CA   . ASP A 1 407 ? -6.367  -13.822 40.374 1.00 18.65 ?  373  ASP A CA   1 
ATOM   5561  C C    . ASP A 1 407 ? -6.712  -12.450 40.931 1.00 16.60 ?  373  ASP A C    1 
ATOM   5562  O O    . ASP A 1 407 ? -5.893  -11.838 41.637 1.00 18.99 ?  373  ASP A O    1 
ATOM   5563  C CB   . ASP A 1 407 ? -6.414  -14.850 41.523 1.00 18.61 ?  373  ASP A CB   1 
ATOM   5564  C CG   . ASP A 1 407 ? -6.254  -16.290 41.040 1.00 28.86 ?  373  ASP A CG   1 
ATOM   5565  O OD1  . ASP A 1 407 ? -6.578  -16.596 39.880 1.00 27.37 ?  373  ASP A OD1  1 
ATOM   5566  O OD2  . ASP A 1 407 ? -5.783  -17.118 41.838 1.00 36.47 ?  373  ASP A OD2  1 
ATOM   5567  H H    . ASP A 1 407 ? -4.422  -13.674 40.361 1.00 20.53 ?  373  ASP A H    1 
ATOM   5568  H HA   . ASP A 1 407 ? -7.015  -14.065 39.694 1.00 22.38 ?  373  ASP A HA   1 
ATOM   5569  H HB2  . ASP A 1 407 ? -5.695  -14.661 42.145 1.00 22.33 ?  373  ASP A HB2  1 
ATOM   5570  H HB3  . ASP A 1 407 ? -7.270  -14.779 41.974 1.00 22.33 ?  373  ASP A HB3  1 
ATOM   5571  N N    . VAL A 1 408 ? -7.897  -11.973 40.612 1.00 17.24 ?  374  VAL A N    1 
ATOM   5572  C CA   . VAL A 1 408 ? -8.363  -10.650 41.026 1.00 17.60 ?  374  VAL A CA   1 
ATOM   5573  C C    . VAL A 1 408 ? -9.495  -10.824 42.025 1.00 19.75 ?  374  VAL A C    1 
ATOM   5574  O O    . VAL A 1 408 ? -10.449 -11.566 41.769 1.00 18.26 ?  374  VAL A O    1 
ATOM   5575  C CB   . VAL A 1 408 ? -8.869  -9.866  39.802 1.00 16.73 ?  374  VAL A CB   1 
ATOM   5576  C CG1  . VAL A 1 408 ? -9.374  -8.472  40.206 1.00 18.67 ?  374  VAL A CG1  1 
ATOM   5577  C CG2  . VAL A 1 408 ? -7.805  -9.745  38.780 1.00 17.31 ?  374  VAL A CG2  1 
ATOM   5578  H H    . VAL A 1 408 ? -8.472  -12.405 40.141 1.00 20.69 ?  374  VAL A H    1 
ATOM   5579  H HA   . VAL A 1 408 ? -7.641  -10.169 41.459 1.00 21.12 ?  374  VAL A HA   1 
ATOM   5580  H HB   . VAL A 1 408 ? -9.612  -10.356 39.417 1.00 20.08 ?  374  VAL A HB   1 
ATOM   5581  H HG11 . VAL A 1 408 ? -9.651  -7.993  39.409 1.00 22.40 ?  374  VAL A HG11 1 
ATOM   5582  H HG12 . VAL A 1 408 ? -10.126 -8.572  40.810 1.00 22.40 ?  374  VAL A HG12 1 
ATOM   5583  H HG13 . VAL A 1 408 ? -8.656  -7.992  40.648 1.00 22.40 ?  374  VAL A HG13 1 
ATOM   5584  H HG21 . VAL A 1 408 ? -8.158  -9.271  38.011 1.00 20.77 ?  374  VAL A HG21 1 
ATOM   5585  H HG22 . VAL A 1 408 ? -7.059  -9.254  39.158 1.00 20.77 ?  374  VAL A HG22 1 
ATOM   5586  H HG23 . VAL A 1 408 ? -7.517  -10.633 38.517 1.00 20.77 ?  374  VAL A HG23 1 
ATOM   5587  N N    . TRP A 1 409 ? -9.430  -10.073 43.124 1.00 20.09 ?  375  TRP A N    1 
ATOM   5588  C CA   . TRP A 1 409 ? -10.528 -9.923  44.058 1.00 20.61 ?  375  TRP A CA   1 
ATOM   5589  C C    . TRP A 1 409 ? -10.744 -8.430  44.274 1.00 17.25 ?  375  TRP A C    1 
ATOM   5590  O O    . TRP A 1 409 ? -9.771  -7.705  44.496 1.00 19.77 ?  375  TRP A O    1 
ATOM   5591  C CB   . TRP A 1 409 ? -10.193 -10.649 45.383 1.00 19.58 ?  375  TRP A CB   1 
ATOM   5592  C CG   . TRP A 1 409 ? -11.228 -10.484 46.478 1.00 21.20 ?  375  TRP A CG   1 
ATOM   5593  C CD1  . TRP A 1 409 ? -12.277 -11.316 46.748 1.00 24.82 ?  375  TRP A CD1  1 
ATOM   5594  C CD2  . TRP A 1 409 ? -11.290 -9.435  47.449 1.00 23.95 ?  375  TRP A CD2  1 
ATOM   5595  N NE1  . TRP A 1 409 ? -12.992 -10.839 47.826 1.00 24.57 ?  375  TRP A NE1  1 
ATOM   5596  C CE2  . TRP A 1 409 ? -12.407 -9.686  48.273 1.00 25.05 ?  375  TRP A CE2  1 
ATOM   5597  C CE3  . TRP A 1 409 ? -10.508 -8.306  47.703 1.00 25.13 ?  375  TRP A CE3  1 
ATOM   5598  C CZ2  . TRP A 1 409 ? -12.760 -8.846  49.328 1.00 27.42 ?  375  TRP A CZ2  1 
ATOM   5599  C CZ3  . TRP A 1 409 ? -10.859 -7.477  48.752 1.00 29.58 ?  375  TRP A CZ3  1 
ATOM   5600  C CH2  . TRP A 1 409 ? -11.978 -7.750  49.547 1.00 26.42 ?  375  TRP A CH2  1 
ATOM   5601  H H    . TRP A 1 409 ? -8.731  -9.627  43.352 1.00 24.11 ?  375  TRP A H    1 
ATOM   5602  H HA   . TRP A 1 409 ? -11.353 -10.300 43.714 1.00 24.73 ?  375  TRP A HA   1 
ATOM   5603  H HB2  . TRP A 1 409 ? -10.110 -11.599 45.201 1.00 23.49 ?  375  TRP A HB2  1 
ATOM   5604  H HB3  . TRP A 1 409 ? -9.353  -10.302 45.721 1.00 23.49 ?  375  TRP A HB3  1 
ATOM   5605  H HD1  . TRP A 1 409 ? -12.479 -12.091 46.274 1.00 29.78 ?  375  TRP A HD1  1 
ATOM   5606  H HE1  . TRP A 1 409 ? -13.693 -11.206 48.163 1.00 29.48 ?  375  TRP A HE1  1 
ATOM   5607  H HE3  . TRP A 1 409 ? -9.766  -8.116  47.176 1.00 30.15 ?  375  TRP A HE3  1 
ATOM   5608  H HZ2  . TRP A 1 409 ? -13.501 -9.026  49.861 1.00 32.90 ?  375  TRP A HZ2  1 
ATOM   5609  H HZ3  . TRP A 1 409 ? -10.342 -6.725  48.932 1.00 35.50 ?  375  TRP A HZ3  1 
ATOM   5610  H HH2  . TRP A 1 409 ? -12.194 -7.170  50.242 1.00 31.70 ?  375  TRP A HH2  1 
ATOM   5611  N N    . LEU A 1 410 ? -11.995 -7.994  44.210 1.00 18.73 ?  376  LEU A N    1 
ATOM   5612  C CA   . LEU A 1 410 ? -12.355 -6.579  44.288 1.00 19.79 ?  376  LEU A CA   1 
ATOM   5613  C C    . LEU A 1 410 ? -13.553 -6.397  45.205 1.00 21.42 ?  376  LEU A C    1 
ATOM   5614  O O    . LEU A 1 410 ? -14.561 -7.087  45.041 1.00 23.13 ?  376  LEU A O    1 
ATOM   5615  C CB   . LEU A 1 410 ? -12.726 -6.073  42.866 1.00 22.13 ?  376  LEU A CB   1 
ATOM   5616  C CG   . LEU A 1 410 ? -13.384 -4.709  42.693 1.00 20.74 ?  376  LEU A CG   1 
ATOM   5617  C CD1  . LEU A 1 410 ? -12.428 -3.622  43.126 1.00 23.03 ?  376  LEU A CD1  1 
ATOM   5618  C CD2  . LEU A 1 410 ? -13.791 -4.477  41.229 1.00 22.55 ?  376  LEU A CD2  1 
ATOM   5619  H H    . LEU A 1 410 ? -12.676 -8.511  44.120 1.00 22.47 ?  376  LEU A H    1 
ATOM   5620  H HA   . LEU A 1 410 ? -11.618 -6.068  44.657 1.00 23.75 ?  376  LEU A HA   1 
ATOM   5621  H HB2  . LEU A 1 410 ? -11.905 -6.045  42.349 1.00 26.56 ?  376  LEU A HB2  1 
ATOM   5622  H HB3  . LEU A 1 410 ? -13.338 -6.720  42.482 1.00 26.56 ?  376  LEU A HB3  1 
ATOM   5623  H HG   . LEU A 1 410 ? -14.184 -4.676  43.241 1.00 24.88 ?  376  LEU A HG   1 
ATOM   5624  H HD11 . LEU A 1 410 ? -12.859 -2.760  43.017 1.00 27.64 ?  376  LEU A HD11 1 
ATOM   5625  H HD12 . LEU A 1 410 ? -12.194 -3.759  44.057 1.00 27.64 ?  376  LEU A HD12 1 
ATOM   5626  H HD13 . LEU A 1 410 ? -11.631 -3.664  42.575 1.00 27.64 ?  376  LEU A HD13 1 
ATOM   5627  H HD21 . LEU A 1 410 ? -14.217 -3.609  41.154 1.00 27.06 ?  376  LEU A HD21 1 
ATOM   5628  H HD22 . LEU A 1 410 ? -12.998 -4.506  40.672 1.00 27.06 ?  376  LEU A HD22 1 
ATOM   5629  H HD23 . LEU A 1 410 ? -14.411 -5.174  40.959 1.00 27.06 ?  376  LEU A HD23 1 
ATOM   5630  N N    . ASN A 1 411 ? -13.477 -5.420  46.128 1.00 20.70 ?  377  ASN A N    1 
ATOM   5631  C CA   . ASN A 1 411 ? -14.615 -5.034  46.962 1.00 21.86 ?  377  ASN A CA   1 
ATOM   5632  C C    . ASN A 1 411 ? -14.892 -3.548  46.776 1.00 20.08 ?  377  ASN A C    1 
ATOM   5633  O O    . ASN A 1 411 ? -14.110 -2.697  47.223 1.00 22.54 ?  377  ASN A O    1 
ATOM   5634  C CB   . ASN A 1 411 ? -14.355 -5.392  48.435 1.00 24.72 ?  377  ASN A CB   1 
ATOM   5635  C CG   . ASN A 1 411 ? -15.562 -5.117  49.323 1.00 28.32 ?  377  ASN A CG   1 
ATOM   5636  O OD1  . ASN A 1 411 ? -16.442 -4.342  48.989 1.00 27.62 ?  377  ASN A OD1  1 
ATOM   5637  N ND2  . ASN A 1 411 ? -15.597 -5.766  50.479 1.00 32.20 ?  377  ASN A ND2  1 
ATOM   5638  H H    . ASN A 1 411 ? -12.765 -4.965  46.285 1.00 24.84 ?  377  ASN A H    1 
ATOM   5639  H HA   . ASN A 1 411 ? -15.407 -5.510  46.668 1.00 26.23 ?  377  ASN A HA   1 
ATOM   5640  H HB2  . ASN A 1 411 ? -14.143 -6.337  48.499 1.00 29.66 ?  377  ASN A HB2  1 
ATOM   5641  H HB3  . ASN A 1 411 ? -13.612 -4.863  48.763 1.00 29.66 ?  377  ASN A HB3  1 
ATOM   5642  H HD21 . ASN A 1 411 ? -16.256 -5.648  51.019 1.00 38.64 ?  377  ASN A HD21 1 
ATOM   5643  H HD22 . ASN A 1 411 ? -14.961 -6.306  50.689 1.00 38.64 ?  377  ASN A HD22 1 
ATOM   5644  N N    . LEU A 1 412 ? -15.998 -3.237  46.112 1.00 19.78 ?  378  LEU A N    1 
ATOM   5645  C CA   . LEU A 1 412 ? -16.320 -1.846  45.817 1.00 20.29 ?  378  LEU A CA   1 
ATOM   5646  C C    . LEU A 1 412 ? -16.708 -1.083  47.072 1.00 26.76 ?  378  LEU A C    1 
ATOM   5647  O O    . LEU A 1 412 ? -16.514 0.133   47.130 1.00 26.07 ?  378  LEU A O    1 
ATOM   5648  C CB   . LEU A 1 412 ? -17.459 -1.752  44.808 1.00 21.49 ?  378  LEU A CB   1 
ATOM   5649  C CG   . LEU A 1 412 ? -17.261 -2.362  43.405 1.00 19.68 ?  378  LEU A CG   1 
ATOM   5650  C CD1  . LEU A 1 412 ? -18.531 -2.212  42.611 1.00 22.06 ?  378  LEU A CD1  1 
ATOM   5651  C CD2  . LEU A 1 412 ? -16.099 -1.685  42.685 1.00 20.77 ?  378  LEU A CD2  1 
ATOM   5652  H H    . LEU A 1 412 ? -16.574 -3.806  45.824 1.00 23.74 ?  378  LEU A H    1 
ATOM   5653  H HA   . LEU A 1 412 ? -15.532 -1.439  45.426 1.00 24.35 ?  378  LEU A HA   1 
ATOM   5654  H HB2  . LEU A 1 412 ? -18.229 -2.196  45.195 1.00 25.79 ?  378  LEU A HB2  1 
ATOM   5655  H HB3  . LEU A 1 412 ? -17.652 -0.811  44.674 1.00 25.79 ?  378  LEU A HB3  1 
ATOM   5656  H HG   . LEU A 1 412 ? -17.049 -3.305  43.485 1.00 23.62 ?  378  LEU A HG   1 
ATOM   5657  H HD11 . LEU A 1 412 ? -18.386 -2.557  41.716 1.00 26.47 ?  378  LEU A HD11 1 
ATOM   5658  H HD12 . LEU A 1 412 ? -19.237 -2.712  43.049 1.00 26.47 ?  378  LEU A HD12 1 
ATOM   5659  H HD13 . LEU A 1 412 ? -18.768 -1.272  42.569 1.00 26.47 ?  378  LEU A HD13 1 
ATOM   5660  H HD21 . LEU A 1 412 ? -16.077 -1.989  41.765 1.00 24.93 ?  378  LEU A HD21 1 
ATOM   5661  H HD22 . LEU A 1 412 ? -16.227 -0.724  42.713 1.00 24.93 ?  378  LEU A HD22 1 
ATOM   5662  H HD23 . LEU A 1 412 ? -15.270 -1.921  43.132 1.00 24.93 ?  378  LEU A HD23 1 
ATOM   5663  N N    . GLU A 1 413 ? -17.256 -1.771  48.078 1.00 24.55 ?  379  GLU A N    1 
ATOM   5664  C CA   . GLU A 1 413 ? -17.706 -1.068  49.281 1.00 29.31 ?  379  GLU A CA   1 
ATOM   5665  C C    . GLU A 1 413 ? -16.528 -0.550  50.084 1.00 23.16 ?  379  GLU A C    1 
ATOM   5666  O O    . GLU A 1 413 ? -16.526 0.604   50.514 1.00 29.74 ?  379  GLU A O    1 
ATOM   5667  C CB   . GLU A 1 413 ? -18.541 -1.985  50.165 1.00 36.09 ?  379  GLU A CB   1 
ATOM   5668  C CG   . GLU A 1 413 ? -19.916 -2.238  49.650 1.00 43.28 ?  379  GLU A CG   1 
ATOM   5669  C CD   . GLU A 1 413 ? -20.941 -2.214  50.760 1.00 45.63 ?  379  GLU A CD   1 
ATOM   5670  O OE1  . GLU A 1 413 ? -21.473 -1.121  51.049 1.00 54.68 ?  379  GLU A OE1  1 
ATOM   5671  O OE2  . GLU A 1 413 ? -21.191 -3.284  51.352 1.00 53.43 ?  379  GLU A OE2  1 
ATOM   5672  H H    . GLU A 1 413 ? -17.377 -2.622  48.089 1.00 29.46 ?  379  GLU A H    1 
ATOM   5673  H HA   . GLU A 1 413 ? -18.257 -0.323  48.997 1.00 35.18 ?  379  GLU A HA   1 
ATOM   5674  H HB2  . GLU A 1 413 ? -18.092 -2.842  50.236 1.00 43.31 ?  379  GLU A HB2  1 
ATOM   5675  H HB3  . GLU A 1 413 ? -18.625 -1.580  51.042 1.00 43.31 ?  379  GLU A HB3  1 
ATOM   5676  H HG2  . GLU A 1 413 ? -20.148 -1.550  49.007 1.00 51.94 ?  379  GLU A HG2  1 
ATOM   5677  H HG3  . GLU A 1 413 ? -19.945 -3.110  49.228 1.00 51.94 ?  379  GLU A HG3  1 
ATOM   5678  N N    . THR A 1 414 ? -15.538 -1.406  50.328 1.00 24.44 ?  380  THR A N    1 
ATOM   5679  C CA   . THR A 1 414 ? -14.332 -1.012  51.046 1.00 27.74 ?  380  THR A CA   1 
ATOM   5680  C C    . THR A 1 414 ? -13.312 -0.325  50.153 1.00 23.39 ?  380  THR A C    1 
ATOM   5681  O O    . THR A 1 414 ? -12.325 0.244   50.654 1.00 26.14 ?  380  THR A O    1 
ATOM   5682  C CB   . THR A 1 414 ? -13.711 -2.261  51.659 1.00 29.29 ?  380  THR A CB   1 
ATOM   5683  O OG1  . THR A 1 414 ? -13.448 -3.226  50.625 1.00 25.48 ?  380  THR A OG1  1 
ATOM   5684  C CG2  . THR A 1 414 ? -14.660 -2.872  52.672 1.00 34.50 ?  380  THR A CG2  1 
ATOM   5685  H H    . THR A 1 414 ? -15.542 -2.231  50.085 1.00 29.33 ?  380  THR A H    1 
ATOM   5686  H HA   . THR A 1 414 ? -14.559 -0.390  51.754 1.00 33.28 ?  380  THR A HA   1 
ATOM   5687  H HB   . THR A 1 414 ? -12.883 -2.026  52.105 1.00 35.15 ?  380  THR A HB   1 
ATOM   5688  H HG1  . THR A 1 414 ? -12.776 -2.993  50.179 1.00 30.58 ?  380  THR A HG1  1 
ATOM   5689  H HG21 . THR A 1 414 ? -14.224 -3.605  53.134 1.00 41.41 ?  380  THR A HG21 1 
ATOM   5690  H HG22 . THR A 1 414 ? -14.927 -2.204  53.322 1.00 41.41 ?  380  THR A HG22 1 
ATOM   5691  H HG23 . THR A 1 414 ? -15.451 -3.210  52.224 1.00 41.41 ?  380  THR A HG23 1 
ATOM   5692  N N    . GLN A 1 415 ? -13.543 -0.327  48.838 1.00 22.35 ?  381  GLN A N    1 
ATOM   5693  C CA   . GLN A 1 415 ? -12.596 0.232   47.878 1.00 22.63 ?  381  GLN A CA   1 
ATOM   5694  C C    . GLN A 1 415 ? -11.217 -0.399  48.036 1.00 22.50 ?  381  GLN A C    1 
ATOM   5695  O O    . GLN A 1 415 ? -10.181 0.274   48.072 1.00 25.10 ?  381  GLN A O    1 
ATOM   5696  C CB   . GLN A 1 415 ? -12.569 1.766   47.928 1.00 23.82 ?  381  GLN A CB   1 
ATOM   5697  C CG   . GLN A 1 415 ? -13.952 2.395   47.764 1.00 23.24 ?  381  GLN A CG   1 
ATOM   5698  C CD   . GLN A 1 415 ? -13.912 3.909   47.454 1.00 27.16 ?  381  GLN A CD   1 
ATOM   5699  O OE1  . GLN A 1 415 ? -12.913 4.428   46.960 1.00 32.92 ?  381  GLN A OE1  1 
ATOM   5700  N NE2  . GLN A 1 415 ? -15.011 4.590   47.721 1.00 41.65 ?  381  GLN A NE2  1 
ATOM   5701  H H    . GLN A 1 415 ? -14.253 -0.651  48.475 1.00 26.82 ?  381  GLN A H    1 
ATOM   5702  H HA   . GLN A 1 415 ? -12.894 0.004   46.983 1.00 27.16 ?  381  GLN A HA   1 
ATOM   5703  H HB2  . GLN A 1 415 ? -12.213 2.046   48.786 1.00 28.59 ?  381  GLN A HB2  1 
ATOM   5704  H HB3  . GLN A 1 415 ? -12.004 2.094   47.211 1.00 28.59 ?  381  GLN A HB3  1 
ATOM   5705  H HG2  . GLN A 1 415 ? -14.411 1.955   47.031 1.00 27.88 ?  381  GLN A HG2  1 
ATOM   5706  H HG3  . GLN A 1 415 ? -14.451 2.275   48.587 1.00 27.88 ?  381  GLN A HG3  1 
ATOM   5707  H HE21 . GLN A 1 415 ? -15.696 4.189   48.049 1.00 49.99 ?  381  GLN A HE21 1 
ATOM   5708  H HE22 . GLN A 1 415 ? -15.040 5.436   47.567 1.00 49.99 ?  381  GLN A HE22 1 
ATOM   5709  N N    . THR A 1 416 ? -11.204 -1.736  48.110 1.00 21.78 ?  382  THR A N    1 
ATOM   5710  C CA   . THR A 1 416 ? -9.972  -2.488  48.209 1.00 20.78 ?  382  THR A CA   1 
ATOM   5711  C C    . THR A 1 416 ? -9.977  -3.634  47.196 1.00 20.79 ?  382  THR A C    1 
ATOM   5712  O O    . THR A 1 416 ? -11.031 -4.053  46.707 1.00 22.24 ?  382  THR A O    1 
ATOM   5713  C CB   . THR A 1 416 ? -9.754  -3.097  49.607 1.00 26.93 ?  382  THR A CB   1 
ATOM   5714  O OG1  . THR A 1 416 ? -10.884 -3.898  49.951 1.00 25.98 ?  382  THR A OG1  1 
ATOM   5715  C CG2  . THR A 1 416 ? -9.553  -2.013  50.660 1.00 27.58 ?  382  THR A CG2  1 
ATOM   5716  H H    . THR A 1 416 ? -11.912 -2.226  48.104 1.00 26.14 ?  382  THR A H    1 
ATOM   5717  H HA   . THR A 1 416 ? -9.243  -1.879  48.013 1.00 24.94 ?  382  THR A HA   1 
ATOM   5718  H HB   . THR A 1 416 ? -8.954  -3.645  49.598 1.00 32.31 ?  382  THR A HB   1 
ATOM   5719  H HG1  . THR A 1 416 ? -10.736 -4.311  50.667 1.00 31.17 ?  382  THR A HG1  1 
ATOM   5720  H HG21 . THR A 1 416 ? -9.363  -2.418  51.521 1.00 33.10 ?  382  THR A HG21 1 
ATOM   5721  H HG22 . THR A 1 416 ? -8.810  -1.442  50.410 1.00 33.10 ?  382  THR A HG22 1 
ATOM   5722  H HG23 . THR A 1 416 ? -10.354 -1.472  50.737 1.00 33.10 ?  382  THR A HG23 1 
ATOM   5723  N N    . ALA A 1 417 ? -8.780  -4.119  46.882 1.00 19.99 ?  383  ALA A N    1 
ATOM   5724  C CA   . ALA A 1 417 ? -8.642  -5.235  45.957 1.00 20.62 ?  383  ALA A CA   1 
ATOM   5725  C C    . ALA A 1 417 ? -7.363  -5.982  46.274 1.00 21.08 ?  383  ALA A C    1 
ATOM   5726  O O    . ALA A 1 417 ? -6.449  -5.447  46.908 1.00 25.73 ?  383  ALA A O    1 
ATOM   5727  C CB   . ALA A 1 417 ? -8.571  -4.749  44.504 1.00 21.42 ?  383  ALA A CB   1 
ATOM   5728  H H    . ALA A 1 417 ? -8.036  -3.819  47.190 1.00 23.98 ?  383  ALA A H    1 
ATOM   5729  H HA   . ALA A 1 417 ? -9.401  -5.829  46.068 1.00 24.74 ?  383  ALA A HA   1 
ATOM   5730  H HB1  . ALA A 1 417 ? -8.533  -5.518  43.915 1.00 25.70 ?  383  ALA A HB1  1 
ATOM   5731  H HB2  . ALA A 1 417 ? -9.362  -4.222  44.308 1.00 25.70 ?  383  ALA A HB2  1 
ATOM   5732  H HB3  . ALA A 1 417 ? -7.776  -4.206  44.391 1.00 25.70 ?  383  ALA A HB3  1 
ATOM   5733  N N    . THR A 1 418 ? -7.279  -7.219  45.816 1.00 21.82 ?  384  THR A N    1 
ATOM   5734  C CA   . THR A 1 418 ? -6.018  -7.934  45.831 1.00 25.55 ?  384  THR A CA   1 
ATOM   5735  C C    . THR A 1 418 ? -5.743  -8.468  44.437 1.00 20.24 ?  384  THR A C    1 
ATOM   5736  O O    . THR A 1 418 ? -6.668  -8.917  43.750 1.00 23.93 ?  384  THR A O    1 
ATOM   5737  C CB   . THR A 1 418 ? -6.038  -9.102  46.819 1.00 26.55 ?  384  THR A CB   1 
ATOM   5738  O OG1  . THR A 1 418 ? -7.052  -10.026 46.428 1.00 28.97 ?  384  THR A OG1  1 
ATOM   5739  C CG2  . THR A 1 418 ? -6.339  -8.610  48.235 1.00 28.96 ?  384  THR A CG2  1 
ATOM   5740  H H    . THR A 1 418 ? -7.939  -7.664  45.490 1.00 26.18 ?  384  THR A H    1 
ATOM   5741  H HA   . THR A 1 418 ? -5.307  -7.328  46.094 1.00 30.66 ?  384  THR A HA   1 
ATOM   5742  H HB   . THR A 1 418 ? -5.171  -9.537  46.823 1.00 31.86 ?  384  THR A HB   1 
ATOM   5743  H HG1  . THR A 1 418 ? -7.035  -10.700 46.929 1.00 34.77 ?  384  THR A HG1  1 
ATOM   5744  H HG21 . THR A 1 418 ? -6.350  -9.359  48.851 1.00 34.75 ?  384  THR A HG21 1 
ATOM   5745  H HG22 . THR A 1 418 ? -5.659  -7.979  48.519 1.00 34.75 ?  384  THR A HG22 1 
ATOM   5746  H HG23 . THR A 1 418 ? -7.204  -8.171  48.257 1.00 34.75 ?  384  THR A HG23 1 
ATOM   5747  N N    . LEU A 1 419 ? -4.488  -8.383  44.031 1.00 21.67 ?  385  LEU A N    1 
ATOM   5748  C CA   . LEU A 1 419 ? -3.997  -8.956  42.783 1.00 22.29 ?  385  LEU A CA   1 
ATOM   5749  C C    . LEU A 1 419 ? -2.981  -10.015 43.180 1.00 21.15 ?  385  LEU A C    1 
ATOM   5750  O O    . LEU A 1 419 ? -1.882  -9.694  43.653 1.00 22.13 ?  385  LEU A O    1 
ATOM   5751  C CB   . LEU A 1 419 ? -3.350  -7.896  41.898 1.00 20.23 ?  385  LEU A CB   1 
ATOM   5752  C CG   . LEU A 1 419 ? -4.251  -6.732  41.462 1.00 20.47 ?  385  LEU A CG   1 
ATOM   5753  C CD1  . LEU A 1 419 ? -3.488  -5.775  40.544 1.00 20.21 ?  385  LEU A CD1  1 
ATOM   5754  C CD2  . LEU A 1 419 ? -5.540  -7.211  40.800 1.00 19.50 ?  385  LEU A CD2  1 
ATOM   5755  H H    . LEU A 1 419 ? -3.873  -7.981  44.478 1.00 26.01 ?  385  LEU A H    1 
ATOM   5756  H HA   . LEU A 1 419 ? -4.725  -9.355  42.282 1.00 26.75 ?  385  LEU A HA   1 
ATOM   5757  H HB2  . LEU A 1 419 ? -2.603  -7.513  42.383 1.00 24.28 ?  385  LEU A HB2  1 
ATOM   5758  H HB3  . LEU A 1 419 ? -3.034  -8.330  41.090 1.00 24.28 ?  385  LEU A HB3  1 
ATOM   5759  H HG   . LEU A 1 419 ? -4.515  -6.246  42.260 1.00 24.57 ?  385  LEU A HG   1 
ATOM   5760  H HD11 . LEU A 1 419 ? -4.079  -5.054  40.277 1.00 24.25 ?  385  LEU A HD11 1 
ATOM   5761  H HD12 . LEU A 1 419 ? -2.725  -5.418  41.024 1.00 24.25 ?  385  LEU A HD12 1 
ATOM   5762  H HD13 . LEU A 1 419 ? -3.187  -6.263  39.761 1.00 24.25 ?  385  LEU A HD13 1 
ATOM   5763  H HD21 . LEU A 1 419 ? -6.035  -6.442  40.477 1.00 23.40 ?  385  LEU A HD21 1 
ATOM   5764  H HD22 . LEU A 1 419 ? -5.316  -7.795  40.058 1.00 23.40 ?  385  LEU A HD22 1 
ATOM   5765  H HD23 . LEU A 1 419 ? -6.070  -7.695  41.453 1.00 23.40 ?  385  LEU A HD23 1 
ATOM   5766  N N    . THR A 1 420 ? -3.352  -11.280 42.997 1.00 20.62 ?  386  THR A N    1 
ATOM   5767  C CA   . THR A 1 420 ? -2.457  -12.378 43.340 1.00 22.39 ?  386  THR A CA   1 
ATOM   5768  C C    . THR A 1 420 ? -1.832  -12.872 42.050 1.00 17.83 ?  386  THR A C    1 
ATOM   5769  O O    . THR A 1 420 ? -2.458  -13.631 41.295 1.00 19.68 ?  386  THR A O    1 
ATOM   5770  C CB   . THR A 1 420 ? -3.231  -13.482 44.040 1.00 21.85 ?  386  THR A CB   1 
ATOM   5771  O OG1  . THR A 1 420 ? -3.931  -12.939 45.156 1.00 24.80 ?  386  THR A OG1  1 
ATOM   5772  C CG2  . THR A 1 420 ? -2.272  -14.575 44.487 1.00 25.69 ?  386  THR A CG2  1 
ATOM   5773  H H    . THR A 1 420 ? -4.112  -11.524 42.678 1.00 24.74 ?  386  THR A H    1 
ATOM   5774  H HA   . THR A 1 420 ? -1.754  -12.067 43.930 1.00 26.86 ?  386  THR A HA   1 
ATOM   5775  H HB   . THR A 1 420 ? -3.879  -13.878 43.437 1.00 26.23 ?  386  THR A HB   1 
ATOM   5776  H HG1  . THR A 1 420 ? -4.576  -12.472 44.891 1.00 29.76 ?  386  THR A HG1  1 
ATOM   5777  H HG21 . THR A 1 420 ? -2.735  -15.211 45.054 1.00 30.82 ?  386  THR A HG21 1 
ATOM   5778  H HG22 . THR A 1 420 ? -1.916  -15.041 43.714 1.00 30.82 ?  386  THR A HG22 1 
ATOM   5779  H HG23 . THR A 1 420 ? -1.536  -14.187 44.986 1.00 30.82 ?  386  THR A HG23 1 
ATOM   5780  N N    . TRP A 1 421 ? -0.613  -12.446 41.802 1.00 20.94 ?  387  TRP A N    1 
ATOM   5781  C CA   . TRP A 1 421 ? 0.098   -12.808 40.596 1.00 20.19 ?  387  TRP A CA   1 
ATOM   5782  C C    . TRP A 1 421 ? 0.651   -14.217 40.742 1.00 21.59 ?  387  TRP A C    1 
ATOM   5783  O O    . TRP A 1 421 ? 1.145   -14.588 41.811 1.00 24.71 ?  387  TRP A O    1 
ATOM   5784  C CB   . TRP A 1 421 ? 1.231   -11.810 40.332 1.00 22.65 ?  387  TRP A CB   1 
ATOM   5785  C CG   . TRP A 1 421 ? 0.764   -10.361 40.222 1.00 20.22 ?  387  TRP A CG   1 
ATOM   5786  C CD1  . TRP A 1 421 ? 0.676   -9.456  41.234 1.00 19.93 ?  387  TRP A CD1  1 
ATOM   5787  C CD2  . TRP A 1 421 ? 0.298   -9.698  39.038 1.00 19.87 ?  387  TRP A CD2  1 
ATOM   5788  N NE1  . TRP A 1 421 ? 0.187   -8.247  40.748 1.00 19.97 ?  387  TRP A NE1  1 
ATOM   5789  C CE2  . TRP A 1 421 ? -0.029  -8.371  39.404 1.00 19.93 ?  387  TRP A CE2  1 
ATOM   5790  C CE3  . TRP A 1 421 ? 0.164   -10.085 37.709 1.00 18.49 ?  387  TRP A CE3  1 
ATOM   5791  C CZ2  . TRP A 1 421 ? -0.507  -7.443  38.487 1.00 19.55 ?  387  TRP A CZ2  1 
ATOM   5792  C CZ3  . TRP A 1 421 ? -0.314  -9.159  36.781 1.00 18.50 ?  387  TRP A CZ3  1 
ATOM   5793  C CH2  . TRP A 1 421 ? -0.630  -7.845  37.181 1.00 20.21 ?  387  TRP A CH2  1 
ATOM   5794  H H    . TRP A 1 421 ? -0.164  -11.934 42.327 1.00 25.12 ?  387  TRP A H    1 
ATOM   5795  H HA   . TRP A 1 421 ? -0.497  -12.787 39.830 1.00 24.23 ?  387  TRP A HA   1 
ATOM   5796  H HB2  . TRP A 1 421 ? 1.867   -11.860 41.062 1.00 27.18 ?  387  TRP A HB2  1 
ATOM   5797  H HB3  . TRP A 1 421 ? 1.664   -12.044 39.497 1.00 27.18 ?  387  TRP A HB3  1 
ATOM   5798  H HD1  . TRP A 1 421 ? 0.907   -9.620  42.119 1.00 23.91 ?  387  TRP A HD1  1 
ATOM   5799  H HE1  . TRP A 1 421 ? 0.045   -7.539  41.216 1.00 23.96 ?  387  TRP A HE1  1 
ATOM   5800  H HE3  . TRP A 1 421 ? 0.389   -10.947 37.443 1.00 22.19 ?  387  TRP A HE3  1 
ATOM   5801  H HZ2  . TRP A 1 421 ? -0.737  -6.581  38.750 1.00 23.46 ?  387  TRP A HZ2  1 
ATOM   5802  H HZ3  . TRP A 1 421 ? -0.425  -9.411  35.893 1.00 22.20 ?  387  TRP A HZ3  1 
ATOM   5803  H HH2  . TRP A 1 421 ? -0.928  -7.236  36.545 1.00 24.25 ?  387  TRP A HH2  1 
ATOM   5804  N N    . LYS A 1 422 ? 0.624   -14.965 39.648 1.00 21.51 ?  388  LYS A N    1 
ATOM   5805  C CA   . LYS A 1 422 ? 1.099   -16.351 39.614 1.00 24.07 ?  388  LYS A CA   1 
ATOM   5806  C C    . LYS A 1 422 ? 2.340   -16.361 38.766 1.00 27.74 ?  388  LYS A C    1 
ATOM   5807  O O    . LYS A 1 422 ? 2.289   -15.955 37.593 1.00 35.27 ?  388  LYS A O    1 
ATOM   5808  C CB   . LYS A 1 422 ? 0.068   -17.292 38.976 1.00 27.30 ?  388  LYS A CB   1 
ATOM   5809  C CG   . LYS A 1 422 ? -1.346  -17.177 39.528 1.00 36.88 ?  388  LYS A CG   1 
ATOM   5810  C CD   . LYS A 1 422 ? -2.362  -18.041 38.754 1.00 40.07 ?  388  LYS A CD   1 
ATOM   5811  H H    . LYS A 1 422 ? 0.329   -14.689 38.888 1.00 25.81 ?  388  LYS A H    1 
ATOM   5812  H HA   . LYS A 1 422 ? 1.259   -16.677 40.513 1.00 28.89 ?  388  LYS A HA   1 
ATOM   5813  H HB2  . LYS A 1 422 ? 0.024   -17.099 38.026 1.00 32.76 ?  388  LYS A HB2  1 
ATOM   5814  H HB3  . LYS A 1 422 ? 0.360   -18.206 39.115 1.00 32.76 ?  388  LYS A HB3  1 
ATOM   5815  H HG2  . LYS A 1 422 ? -1.348  -17.468 40.453 1.00 44.25 ?  388  LYS A HG2  1 
ATOM   5816  H HG3  . LYS A 1 422 ? -1.633  -16.252 39.470 1.00 44.25 ?  388  LYS A HG3  1 
ATOM   5817  H HD2  . LYS A 1 422 ? -1.953  -18.363 37.936 1.00 48.09 ?  388  LYS A HD2  1 
ATOM   5818  H HD3  . LYS A 1 422 ? -2.632  -18.790 39.307 1.00 48.09 ?  388  LYS A HD3  1 
ATOM   5819  N N    . ILE B 1 57  ? 0.369   55.017  63.592 1.00 45.87 ?  23   ILE B N    1 
ATOM   5820  C CA   . ILE B 1 57  ? -0.075  54.477  62.306 1.00 34.46 ?  23   ILE B CA   1 
ATOM   5821  C C    . ILE B 1 57  ? -0.895  55.514  61.551 1.00 25.79 ?  23   ILE B C    1 
ATOM   5822  O O    . ILE B 1 57  ? -1.804  56.139  62.102 1.00 31.53 ?  23   ILE B O    1 
ATOM   5823  C CB   . ILE B 1 57  ? -0.867  53.160  62.477 1.00 39.49 ?  23   ILE B CB   1 
ATOM   5824  C CG1  . ILE B 1 57  ? 0.070   52.044  62.940 1.00 38.40 ?  23   ILE B CG1  1 
ATOM   5825  C CG2  . ILE B 1 57  ? -1.543  52.757  61.162 1.00 29.14 ?  23   ILE B CG2  1 
ATOM   5826  C CD1  . ILE B 1 57  ? -0.076  51.722  64.383 1.00 59.65 ?  23   ILE B CD1  1 
ATOM   5827  H HA   . ILE B 1 57  ? 0.712   54.271  61.778 1.00 41.35 ?  23   ILE B HA   1 
ATOM   5828  H HB   . ILE B 1 57  ? -1.554  53.304  63.147 1.00 47.39 ?  23   ILE B HB   1 
ATOM   5829  H HG12 . ILE B 1 57  ? -0.125  51.239  62.434 1.00 46.08 ?  23   ILE B HG12 1 
ATOM   5830  H HG13 . ILE B 1 57  ? 0.987   52.319  62.786 1.00 46.08 ?  23   ILE B HG13 1 
ATOM   5831  H HG21 . ILE B 1 57  ? -1.851  51.839  61.234 1.00 34.97 ?  23   ILE B HG21 1 
ATOM   5832  H HG22 . ILE B 1 57  ? -2.296  53.346  61.001 1.00 34.97 ?  23   ILE B HG22 1 
ATOM   5833  H HG23 . ILE B 1 57  ? -0.900  52.835  60.440 1.00 34.97 ?  23   ILE B HG23 1 
ATOM   5834  H HD11 . ILE B 1 57  ? 0.475   50.952  64.592 1.00 71.58 ?  23   ILE B HD11 1 
ATOM   5835  H HD12 . ILE B 1 57  ? 0.211   52.486  64.907 1.00 71.58 ?  23   ILE B HD12 1 
ATOM   5836  H HD13 . ILE B 1 57  ? -1.007  51.524  64.570 1.00 71.58 ?  23   ILE B HD13 1 
ATOM   5837  N N    . ASP B 1 58  ? -0.571  55.670  60.275 1.00 26.45 ?  24   ASP B N    1 
ATOM   5838  C CA   . ASP B 1 58  ? -1.267  56.594  59.387 1.00 23.03 ?  24   ASP B CA   1 
ATOM   5839  C C    . ASP B 1 58  ? -2.451  55.843  58.786 1.00 22.25 ?  24   ASP B C    1 
ATOM   5840  O O    . ASP B 1 58  ? -2.272  54.940  57.958 1.00 22.40 ?  24   ASP B O    1 
ATOM   5841  C CB   . ASP B 1 58  ? -0.312  57.086  58.312 1.00 26.45 ?  24   ASP B CB   1 
ATOM   5842  C CG   . ASP B 1 58  ? -0.968  58.045  57.337 1.00 24.37 ?  24   ASP B CG   1 
ATOM   5843  O OD1  . ASP B 1 58  ? -2.172  58.351  57.489 1.00 22.17 ?  24   ASP B OD1  1 
ATOM   5844  O OD2  . ASP B 1 58  ? -0.268  58.486  56.393 1.00 25.89 ?  24   ASP B OD2  1 
ATOM   5845  H H    . ASP B 1 58  ? 0.066   55.241  59.888 1.00 31.74 ?  24   ASP B H    1 
ATOM   5846  H HA   . ASP B 1 58  ? -1.599  57.363  59.875 1.00 27.64 ?  24   ASP B HA   1 
ATOM   5847  H HB2  . ASP B 1 58  ? 0.428   57.549  58.735 1.00 31.74 ?  24   ASP B HB2  1 
ATOM   5848  H HB3  . ASP B 1 58  ? 0.016   56.325  57.809 1.00 31.74 ?  24   ASP B HB3  1 
ATOM   5849  N N    . TYR B 1 59  ? -3.650  56.186  59.238 1.00 21.51 ?  25   TYR B N    1 
ATOM   5850  C CA   . TYR B 1 59  ? -4.887  55.622  58.725 1.00 17.19 ?  25   TYR B CA   1 
ATOM   5851  C C    . TYR B 1 59  ? -5.542  56.472  57.654 1.00 17.27 ?  25   TYR B C    1 
ATOM   5852  O O    . TYR B 1 59  ? -6.664  56.178  57.240 1.00 19.33 ?  25   TYR B O    1 
ATOM   5853  C CB   . TYR B 1 59  ? -5.893  55.416  59.868 1.00 20.00 ?  25   TYR B CB   1 
ATOM   5854  C CG   . TYR B 1 59  ? -5.467  54.400  60.894 1.00 21.53 ?  25   TYR B CG   1 
ATOM   5855  C CD1  . TYR B 1 59  ? -5.385  53.050  60.575 1.00 20.45 ?  25   TYR B CD1  1 
ATOM   5856  C CD2  . TYR B 1 59  ? -5.150  54.772  62.192 1.00 24.70 ?  25   TYR B CD2  1 
ATOM   5857  C CE1  . TYR B 1 59  ? -5.019  52.109  61.525 1.00 22.07 ?  25   TYR B CE1  1 
ATOM   5858  C CE2  . TYR B 1 59  ? -4.759  53.823  63.143 1.00 23.79 ?  25   TYR B CE2  1 
ATOM   5859  C CZ   . TYR B 1 59  ? -4.699  52.487  62.804 1.00 22.09 ?  25   TYR B CZ   1 
ATOM   5860  O OH   . TYR B 1 59  ? -4.325  51.527  63.744 1.00 23.24 ?  25   TYR B OH   1 
ATOM   5861  H H    . TYR B 1 59  ? -3.775  56.763  59.862 1.00 25.82 ?  25   TYR B H    1 
ATOM   5862  H HA   . TYR B 1 59  ? -4.668  54.761  58.335 1.00 20.62 ?  25   TYR B HA   1 
ATOM   5863  H HB2  . TYR B 1 59  ? -6.018  56.261  60.327 1.00 24.00 ?  25   TYR B HB2  1 
ATOM   5864  H HB3  . TYR B 1 59  ? -6.734  55.116  59.490 1.00 24.00 ?  25   TYR B HB3  1 
ATOM   5865  H HD1  . TYR B 1 59  ? -5.578  52.773  59.709 1.00 24.54 ?  25   TYR B HD1  1 
ATOM   5866  H HD2  . TYR B 1 59  ? -5.198  55.668  62.434 1.00 29.64 ?  25   TYR B HD2  1 
ATOM   5867  H HE1  . TYR B 1 59  ? -4.991  51.209  61.293 1.00 26.48 ?  25   TYR B HE1  1 
ATOM   5868  H HE2  . TYR B 1 59  ? -4.540  54.094  64.005 1.00 28.55 ?  25   TYR B HE2  1 
ATOM   5869  H HH   . TYR B 1 59  ? -4.197  51.890  64.490 1.00 27.89 ?  25   TYR B HH   1 
ATOM   5870  N N    . SER B 1 60  ? -4.886  57.545  57.207 1.00 19.48 ?  26   SER B N    1 
ATOM   5871  C CA   . SER B 1 60  ? -5.577  58.517  56.368 1.00 17.05 ?  26   SER B CA   1 
ATOM   5872  C C    . SER B 1 60  ? -6.013  57.949  55.024 1.00 17.92 ?  26   SER B C    1 
ATOM   5873  O O    . SER B 1 60  ? -6.946  58.479  54.415 1.00 19.18 ?  26   SER B O    1 
ATOM   5874  C CB   . SER B 1 60  ? -4.722  59.779  56.172 1.00 21.96 ?  26   SER B CB   1 
ATOM   5875  O OG   . SER B 1 60  ? -3.562  59.513  55.403 1.00 22.94 ?  26   SER B OG   1 
ATOM   5876  H H    . SER B 1 60  ? -4.062  57.726  57.372 1.00 23.37 ?  26   SER B H    1 
ATOM   5877  H HA   . SER B 1 60  ? -6.383  58.786  56.835 1.00 20.46 ?  26   SER B HA   1 
ATOM   5878  H HB2  . SER B 1 60  ? -5.254  60.448  55.713 1.00 26.35 ?  26   SER B HB2  1 
ATOM   5879  H HB3  . SER B 1 60  ? -4.451  60.110  57.042 1.00 26.35 ?  26   SER B HB3  1 
ATOM   5880  H HG   . SER B 1 60  ? -3.138  60.225  55.267 1.00 27.53 ?  26   SER B HG   1 
ATOM   5881  N N    . ASN B 1 61  ? -5.372  56.877  54.548 1.00 16.60 ?  27   ASN B N    1 
ATOM   5882  C CA   . ASN B 1 61  ? -5.737  56.281  53.264 1.00 16.43 ?  27   ASN B CA   1 
ATOM   5883  C C    . ASN B 1 61  ? -6.523  54.994  53.411 1.00 15.17 ?  27   ASN B C    1 
ATOM   5884  O O    . ASN B 1 61  ? -6.835  54.356  52.390 1.00 15.99 ?  27   ASN B O    1 
ATOM   5885  C CB   . ASN B 1 61  ? -4.478  56.088  52.437 1.00 15.54 ?  27   ASN B CB   1 
ATOM   5886  C CG   . ASN B 1 61  ? -3.668  57.351  52.370 1.00 18.58 ?  27   ASN B CG   1 
ATOM   5887  O OD1  . ASN B 1 61  ? -4.202  58.408  52.019 1.00 19.88 ?  27   ASN B OD1  1 
ATOM   5888  N ND2  . ASN B 1 61  ? -2.405  57.268  52.732 1.00 19.09 ?  27   ASN B ND2  1 
ATOM   5889  H H    . ASN B 1 61  ? -4.725  56.480  54.952 1.00 19.92 ?  27   ASN B H    1 
ATOM   5890  H HA   . ASN B 1 61  ? -6.316  56.885  52.774 1.00 19.71 ?  27   ASN B HA   1 
ATOM   5891  H HB2  . ASN B 1 61  ? -3.932  55.395  52.840 1.00 18.65 ?  27   ASN B HB2  1 
ATOM   5892  H HB3  . ASN B 1 61  ? -4.723  55.834  51.534 1.00 18.65 ?  27   ASN B HB3  1 
ATOM   5893  H HD21 . ASN B 1 61  ? -1.904  57.967  52.709 1.00 22.90 ?  27   ASN B HD21 1 
ATOM   5894  H HD22 . ASN B 1 61  ? -2.080  56.515  52.992 1.00 22.90 ?  27   ASN B HD22 1 
ATOM   5895  N N    . TYR B 1 62  ? -6.937  54.649  54.618 1.00 15.05 ?  28   TYR B N    1 
ATOM   5896  C CA   . TYR B 1 62  ? -7.644  53.401  54.841 1.00 13.76 ?  28   TYR B CA   1 
ATOM   5897  C C    . TYR B 1 62  ? -9.083  53.464  54.333 1.00 15.05 ?  28   TYR B C    1 
ATOM   5898  O O    . TYR B 1 62  ? -9.656  54.538  54.170 1.00 15.91 ?  28   TYR B O    1 
ATOM   5899  C CB   . TYR B 1 62  ? -7.653  53.058  56.323 1.00 15.18 ?  28   TYR B CB   1 
ATOM   5900  C CG   . TYR B 1 62  ? -6.481  52.255  56.822 1.00 14.07 ?  28   TYR B CG   1 
ATOM   5901  C CD1  . TYR B 1 62  ? -5.183  52.526  56.424 1.00 14.79 ?  28   TYR B CD1  1 
ATOM   5902  C CD2  . TYR B 1 62  ? -6.665  51.206  57.730 1.00 14.25 ?  28   TYR B CD2  1 
ATOM   5903  C CE1  . TYR B 1 62  ? -4.112  51.802  56.921 1.00 15.74 ?  28   TYR B CE1  1 
ATOM   5904  C CE2  . TYR B 1 62  ? -5.595  50.491  58.219 1.00 14.54 ?  28   TYR B CE2  1 
ATOM   5905  C CZ   . TYR B 1 62  ? -4.321  50.773  57.806 1.00 15.03 ?  28   TYR B CZ   1 
ATOM   5906  O OH   . TYR B 1 62  ? -3.253  50.060  58.317 1.00 15.81 ?  28   TYR B OH   1 
ATOM   5907  H H    . TYR B 1 62  ? -6.821  55.121  55.327 1.00 18.06 ?  28   TYR B H    1 
ATOM   5908  H HA   . TYR B 1 62  ? -7.186  52.700  54.351 1.00 16.51 ?  28   TYR B HA   1 
ATOM   5909  H HB2  . TYR B 1 62  ? -7.666  53.888  56.826 1.00 18.22 ?  28   TYR B HB2  1 
ATOM   5910  H HB3  . TYR B 1 62  ? -8.453  52.544  56.511 1.00 18.22 ?  28   TYR B HB3  1 
ATOM   5911  H HD1  . TYR B 1 62  ? -5.027  53.208  55.812 1.00 17.74 ?  28   TYR B HD1  1 
ATOM   5912  H HD2  . TYR B 1 62  ? -7.525  50.988  58.009 1.00 17.10 ?  28   TYR B HD2  1 
ATOM   5913  H HE1  . TYR B 1 62  ? -3.247  52.013  56.653 1.00 18.89 ?  28   TYR B HE1  1 
ATOM   5914  H HE2  . TYR B 1 62  ? -5.739  49.810  58.835 1.00 17.45 ?  28   TYR B HE2  1 
ATOM   5915  H HH   . TYR B 1 62  ? -3.516  49.549  58.929 1.00 18.97 ?  28   TYR B HH   1 
ATOM   5916  N N    . PRO B 1 63  ? -9.712  52.304  54.133 1.00 14.71 ?  29   PRO B N    1 
ATOM   5917  C CA   . PRO B 1 63  ? -11.105 52.271  53.709 1.00 12.39 ?  29   PRO B CA   1 
ATOM   5918  C C    . PRO B 1 63  ? -12.035 52.666  54.839 1.00 14.66 ?  29   PRO B C    1 
ATOM   5919  O O    . PRO B 1 63  ? -11.643 52.762  56.007 1.00 16.99 ?  29   PRO B O    1 
ATOM   5920  C CB   . PRO B 1 63  ? -11.343 50.796  53.310 1.00 14.52 ?  29   PRO B CB   1 
ATOM   5921  C CG   . PRO B 1 63  ? -10.032 50.121  53.513 1.00 18.08 ?  29   PRO B CG   1 
ATOM   5922  C CD   . PRO B 1 63  ? -9.170  50.959  54.353 1.00 14.50 ?  29   PRO B CD   1 
ATOM   5923  H HA   . PRO B 1 63  ? -11.235 52.851  52.942 1.00 14.87 ?  29   PRO B HA   1 
ATOM   5924  H HB2  . PRO B 1 63  ? -12.025 50.407  53.880 1.00 17.42 ?  29   PRO B HB2  1 
ATOM   5925  H HB3  . PRO B 1 63  ? -11.618 50.746  52.381 1.00 17.42 ?  29   PRO B HB3  1 
ATOM   5926  H HG2  . PRO B 1 63  ? -10.186 49.267  53.947 1.00 21.69 ?  29   PRO B HG2  1 
ATOM   5927  H HG3  . PRO B 1 63  ? -9.616  49.983  52.648 1.00 21.69 ?  29   PRO B HG3  1 
ATOM   5928  H HD2  . PRO B 1 63  ? -9.241  50.704  55.286 1.00 17.39 ?  29   PRO B HD2  1 
ATOM   5929  H HD3  . PRO B 1 63  ? -8.246  50.906  54.064 1.00 17.39 ?  29   PRO B HD3  1 
ATOM   5930  N N    . GLU B 1 64  ? -13.287 52.888  54.456 1.00 14.15 ?  30   GLU B N    1 
ATOM   5931  C CA   . GLU B 1 64  ? -14.328 53.002  55.473 1.00 13.84 ?  30   GLU B CA   1 
ATOM   5932  C C    . GLU B 1 64  ? -14.438 51.703  56.261 1.00 16.07 ?  30   GLU B C    1 
ATOM   5933  O O    . GLU B 1 64  ? -14.175 50.612  55.748 1.00 15.72 ?  30   GLU B O    1 
ATOM   5934  C CB   . GLU B 1 64  ? -15.676 53.313  54.822 1.00 15.63 ?  30   GLU B CB   1 
ATOM   5935  C CG   . GLU B 1 64  ? -15.683 54.603  53.976 1.00 18.00 ?  30   GLU B CG   1 
ATOM   5936  C CD   . GLU B 1 64  ? -15.366 55.849  54.734 1.00 29.20 ?  30   GLU B CD   1 
ATOM   5937  O OE1  . GLU B 1 64  ? -16.011 56.098  55.775 1.00 27.24 ?  30   GLU B OE1  1 
ATOM   5938  O OE2  . GLU B 1 64  ? -14.474 56.572  54.266 1.00 30.51 ?  30   GLU B OE2  1 
ATOM   5939  H H    . GLU B 1 64  ? -13.552 52.975  53.643 1.00 16.98 ?  30   GLU B H    1 
ATOM   5940  H HA   . GLU B 1 64  ? -14.105 53.724  56.081 1.00 16.60 ?  30   GLU B HA   1 
ATOM   5941  H HB2  . GLU B 1 64  ? -15.916 52.577  54.239 1.00 18.76 ?  30   GLU B HB2  1 
ATOM   5942  H HB3  . GLU B 1 64  ? -16.341 53.415  55.521 1.00 18.76 ?  30   GLU B HB3  1 
ATOM   5943  H HG2  . GLU B 1 64  ? -15.022 54.513  53.272 1.00 21.60 ?  30   GLU B HG2  1 
ATOM   5944  H HG3  . GLU B 1 64  ? -16.566 54.713  53.591 1.00 21.60 ?  30   GLU B HG3  1 
ATOM   5945  N N    . PHE B 1 65  ? -14.882 51.804  57.506 1.00 15.16 ?  31   PHE B N    1 
ATOM   5946  C CA   . PHE B 1 65  ? -15.139 50.638  58.321 1.00 14.90 ?  31   PHE B CA   1 
ATOM   5947  C C    . PHE B 1 65  ? -16.265 50.935  59.296 1.00 15.77 ?  31   PHE B C    1 
ATOM   5948  O O    . PHE B 1 65  ? -16.263 51.992  59.941 1.00 17.09 ?  31   PHE B O    1 
ATOM   5949  C CB   . PHE B 1 65  ? -13.901 50.204  59.105 1.00 14.84 ?  31   PHE B CB   1 
ATOM   5950  C CG   . PHE B 1 65  ? -14.151 48.985  59.945 1.00 13.56 ?  31   PHE B CG   1 
ATOM   5951  C CD1  . PHE B 1 65  ? -13.995 47.717  59.413 1.00 13.55 ?  31   PHE B CD1  1 
ATOM   5952  C CD2  . PHE B 1 65  ? -14.616 49.088  61.255 1.00 15.41 ?  31   PHE B CD2  1 
ATOM   5953  C CE1  . PHE B 1 65  ? -14.255 46.614  60.151 1.00 15.00 ?  31   PHE B CE1  1 
ATOM   5954  C CE2  . PHE B 1 65  ? -14.894 47.980  61.991 1.00 15.03 ?  31   PHE B CE2  1 
ATOM   5955  C CZ   . PHE B 1 65  ? -14.710 46.738  61.445 1.00 14.61 ?  31   PHE B CZ   1 
ATOM   5956  H H    . PHE B 1 65  ? -15.044 52.550  57.903 1.00 18.20 ?  31   PHE B H    1 
ATOM   5957  H HA   . PHE B 1 65  ? -15.412 49.913  57.738 1.00 17.89 ?  31   PHE B HA   1 
ATOM   5958  H HB2  . PHE B 1 65  ? -13.187 49.998  58.481 1.00 17.81 ?  31   PHE B HB2  1 
ATOM   5959  H HB3  . PHE B 1 65  ? -13.629 50.925  59.694 1.00 17.81 ?  31   PHE B HB3  1 
ATOM   5960  H HD1  . PHE B 1 65  ? -13.708 47.622  58.534 1.00 16.25 ?  31   PHE B HD1  1 
ATOM   5961  H HD2  . PHE B 1 65  ? -14.738 49.929  61.632 1.00 18.49 ?  31   PHE B HD2  1 
ATOM   5962  H HE1  . PHE B 1 65  ? -14.125 45.770  59.784 1.00 18.00 ?  31   PHE B HE1  1 
ATOM   5963  H HE2  . PHE B 1 65  ? -15.208 48.066  62.862 1.00 18.03 ?  31   PHE B HE2  1 
ATOM   5964  H HZ   . PHE B 1 65  ? -14.893 45.978  61.948 1.00 17.53 ?  31   PHE B HZ   1 
ATOM   5965  N N    . SER B 1 66  ? -17.177 49.983  59.441 1.00 16.89 ?  32   SER B N    1 
ATOM   5966  C CA   . SER B 1 66  ? -18.200 50.030  60.483 1.00 16.35 ?  32   SER B CA   1 
ATOM   5967  C C    . SER B 1 66  ? -18.403 48.637  61.054 1.00 16.07 ?  32   SER B C    1 
ATOM   5968  O O    . SER B 1 66  ? -18.392 47.653  60.312 1.00 16.48 ?  32   SER B O    1 
ATOM   5969  C CB   . SER B 1 66  ? -19.513 50.556  59.909 1.00 19.25 ?  32   SER B CB   1 
ATOM   5970  O OG   . SER B 1 66  ? -20.499 50.533  60.936 1.00 20.59 ?  32   SER B OG   1 
ATOM   5971  H H    . SER B 1 66  ? -17.227 49.286  58.941 1.00 20.27 ?  32   SER B H    1 
ATOM   5972  H HA   . SER B 1 66  ? -17.916 50.608  61.208 1.00 19.63 ?  32   SER B HA   1 
ATOM   5973  H HB2  . SER B 1 66  ? -19.389 51.466  59.597 1.00 23.10 ?  32   SER B HB2  1 
ATOM   5974  H HB3  . SER B 1 66  ? -19.796 49.990  59.174 1.00 23.10 ?  32   SER B HB3  1 
ATOM   5975  H HG   . SER B 1 66  ? -21.265 50.617  60.600 1.00 24.71 ?  32   SER B HG   1 
ATOM   5976  N N    . TRP B 1 67  ? -18.610 48.556  62.367 1.00 16.16 ?  33   TRP B N    1 
ATOM   5977  C CA   . TRP B 1 67  ? -19.077 47.343  63.020 1.00 15.72 ?  33   TRP B CA   1 
ATOM   5978  C C    . TRP B 1 67  ? -20.589 47.152  62.940 1.00 16.14 ?  33   TRP B C    1 
ATOM   5979  O O    . TRP B 1 67  ? -21.086 46.146  63.443 1.00 16.76 ?  33   TRP B O    1 
ATOM   5980  C CB   . TRP B 1 67  ? -18.697 47.357  64.504 1.00 17.64 ?  33   TRP B CB   1 
ATOM   5981  C CG   . TRP B 1 67  ? -17.231 47.190  64.828 1.00 15.75 ?  33   TRP B CG   1 
ATOM   5982  C CD1  . TRP B 1 67  ? -16.402 48.129  65.380 1.00 17.28 ?  33   TRP B CD1  1 
ATOM   5983  C CD2  . TRP B 1 67  ? -16.439 46.019  64.638 1.00 14.58 ?  33   TRP B CD2  1 
ATOM   5984  N NE1  . TRP B 1 67  ? -15.143 47.603  65.546 1.00 16.60 ?  33   TRP B NE1  1 
ATOM   5985  C CE2  . TRP B 1 67  ? -15.132 46.307  65.110 1.00 15.06 ?  33   TRP B CE2  1 
ATOM   5986  C CE3  . TRP B 1 67  ? -16.697 44.750  64.132 1.00 16.01 ?  33   TRP B CE3  1 
ATOM   5987  C CZ2  . TRP B 1 67  ? -14.118 45.375  65.084 1.00 15.79 ?  33   TRP B CZ2  1 
ATOM   5988  C CZ3  . TRP B 1 67  ? -15.677 43.806  64.105 1.00 13.88 ?  33   TRP B CZ3  1 
ATOM   5989  C CH2  . TRP B 1 67  ? -14.401 44.131  64.573 1.00 17.68 ?  33   TRP B CH2  1 
ATOM   5990  H H    . TRP B 1 67  ? -18.483 49.208  62.913 1.00 19.40 ?  33   TRP B H    1 
ATOM   5991  H HA   . TRP B 1 67  ? -18.640 46.596  62.582 1.00 18.86 ?  33   TRP B HA   1 
ATOM   5992  H HB2  . TRP B 1 67  ? -18.976 48.207  64.879 1.00 21.17 ?  33   TRP B HB2  1 
ATOM   5993  H HB3  . TRP B 1 67  ? -19.169 46.631  64.942 1.00 21.17 ?  33   TRP B HB3  1 
ATOM   5994  H HD1  . TRP B 1 67  ? -16.653 48.994  65.609 1.00 20.74 ?  33   TRP B HD1  1 
ATOM   5995  H HE1  . TRP B 1 67  ? -14.467 48.023  65.872 1.00 19.92 ?  33   TRP B HE1  1 
ATOM   5996  H HE3  . TRP B 1 67  ? -17.545 44.535  63.815 1.00 19.22 ?  33   TRP B HE3  1 
ATOM   5997  H HZ2  . TRP B 1 67  ? -13.269 45.582  65.402 1.00 18.95 ?  33   TRP B HZ2  1 
ATOM   5998  H HZ3  . TRP B 1 67  ? -15.844 42.954  63.774 1.00 16.65 ?  33   TRP B HZ3  1 
ATOM   5999  H HH2  . TRP B 1 67  ? -13.727 43.491  64.539 1.00 21.22 ?  33   TRP B HH2  1 
ATOM   6000  N N    . ASP B 1 68  ? -21.329 48.093  62.351 1.00 17.54 ?  34   ASP B N    1 
ATOM   6001  C CA   . ASP B 1 68  ? -22.793 48.029  62.453 1.00 16.84 ?  34   ASP B CA   1 
ATOM   6002  C C    . ASP B 1 68  ? -23.321 46.709  61.925 1.00 16.50 ?  34   ASP B C    1 
ATOM   6003  O O    . ASP B 1 68  ? -24.226 46.112  62.508 1.00 17.80 ?  34   ASP B O    1 
ATOM   6004  C CB   . ASP B 1 68  ? -23.434 49.167  61.658 1.00 19.52 ?  34   ASP B CB   1 
ATOM   6005  C CG   . ASP B 1 68  ? -23.300 50.527  62.317 1.00 22.57 ?  34   ASP B CG   1 
ATOM   6006  O OD1  . ASP B 1 68  ? -22.778 50.609  63.446 1.00 23.61 ?  34   ASP B OD1  1 
ATOM   6007  O OD2  . ASP B 1 68  ? -23.730 51.513  61.667 1.00 24.84 ?  34   ASP B OD2  1 
ATOM   6008  H H    . ASP B 1 68  ? -21.022 48.759  61.901 1.00 21.04 ?  34   ASP B H    1 
ATOM   6009  H HA   . ASP B 1 68  ? -23.031 48.121  63.388 1.00 20.21 ?  34   ASP B HA   1 
ATOM   6010  H HB2  . ASP B 1 68  ? -23.010 49.217  60.787 1.00 23.42 ?  34   ASP B HB2  1 
ATOM   6011  H HB3  . ASP B 1 68  ? -24.381 48.981  61.555 1.00 23.42 ?  34   ASP B HB3  1 
ATOM   6012  N N    . THR B 1 69  ? -22.786 46.257  60.783 1.00 15.73 ?  35   THR B N    1 
ATOM   6013  C CA   . THR B 1 69  ? -23.079 44.957  60.192 1.00 13.69 ?  35   THR B CA   1 
ATOM   6014  C C    . THR B 1 69  ? -21.763 44.378  59.686 1.00 14.43 ?  35   THR B C    1 
ATOM   6015  O O    . THR B 1 69  ? -20.733 45.048  59.702 1.00 14.95 ?  35   THR B O    1 
ATOM   6016  C CB   . THR B 1 69  ? -24.103 45.070  59.046 1.00 15.11 ?  35   THR B CB   1 
ATOM   6017  O OG1  . THR B 1 69  ? -23.582 45.901  58.012 1.00 16.05 ?  35   THR B OG1  1 
ATOM   6018  C CG2  . THR B 1 69  ? -25.455 45.650  59.564 1.00 17.87 ?  35   THR B CG2  1 
ATOM   6019  H H    . THR B 1 69  ? -22.225 46.711  60.314 1.00 18.88 ?  35   THR B H    1 
ATOM   6020  H HA   . THR B 1 69  ? -23.453 44.373  60.871 1.00 16.43 ?  35   THR B HA   1 
ATOM   6021  H HB   . THR B 1 69  ? -24.278 44.187  58.684 1.00 18.13 ?  35   THR B HB   1 
ATOM   6022  H HG1  . THR B 1 69  ? -23.026 45.472  57.551 1.00 19.26 ?  35   THR B HG1  1 
ATOM   6023  H HG21 . THR B 1 69  ? -26.053 45.814  58.818 1.00 21.45 ?  35   THR B HG21 1 
ATOM   6024  H HG22 . THR B 1 69  ? -25.875 45.020  60.172 1.00 21.45 ?  35   THR B HG22 1 
ATOM   6025  H HG23 . THR B 1 69  ? -25.300 46.484  60.033 1.00 21.45 ?  35   THR B HG23 1 
ATOM   6026  N N    . MET B 1 70  ? -21.819 43.149  59.175 1.00 14.40 ?  36   MET B N    1 
ATOM   6027  C CA   . MET B 1 70  ? -20.580 42.456  58.820 1.00 14.19 ?  36   MET B CA   1 
ATOM   6028  C C    . MET B 1 70  ? -19.730 43.314  57.885 1.00 13.93 ?  36   MET B C    1 
ATOM   6029  O O    . MET B 1 70  ? -20.234 43.777  56.849 1.00 13.91 ?  36   MET B O    1 
ATOM   6030  C CB   . MET B 1 70  ? -20.923 41.156  58.104 1.00 14.21 ?  36   MET B CB   1 
ATOM   6031  C CG   . MET B 1 70  ? -19.763 40.143  58.055 1.00 13.06 ?  36   MET B CG   1 
ATOM   6032  S SD   . MET B 1 70  ? -19.235 39.555  59.680 1.00 14.29 ?  36   MET B SD   1 
ATOM   6033  C CE   . MET B 1 70  ? -20.825 39.047  60.382 1.00 17.00 ?  36   MET B CE   1 
ATOM   6034  H H    . MET B 1 70  ? -22.541 42.706  59.027 1.00 17.28 ?  36   MET B H    1 
ATOM   6035  H HA   . MET B 1 70  ? -20.082 42.268  59.631 1.00 17.02 ?  36   MET B HA   1 
ATOM   6036  H HB2  . MET B 1 70  ? -21.664 40.733  58.565 1.00 17.05 ?  36   MET B HB2  1 
ATOM   6037  H HB3  . MET B 1 70  ? -21.174 41.362  57.190 1.00 17.05 ?  36   MET B HB3  1 
ATOM   6038  H HG2  . MET B 1 70  ? -20.046 39.371  57.539 1.00 15.67 ?  36   MET B HG2  1 
ATOM   6039  H HG3  . MET B 1 70  ? -19.000 40.564  57.630 1.00 15.67 ?  36   MET B HG3  1 
ATOM   6040  H HE1  . MET B 1 70  ? -20.668 38.603  61.230 1.00 20.40 ?  36   MET B HE1  1 
ATOM   6041  H HE2  . MET B 1 70  ? -21.376 39.834  60.517 1.00 20.40 ?  36   MET B HE2  1 
ATOM   6042  H HE3  . MET B 1 70  ? -21.262 38.439  59.766 1.00 20.40 ?  36   MET B HE3  1 
ATOM   6043  N N    . PRO B 1 71  ? -18.434 43.494  58.162 1.00 12.85 ?  37   PRO B N    1 
ATOM   6044  C CA   . PRO B 1 71  ? -17.546 44.235  57.240 1.00 11.59 ?  37   PRO B CA   1 
ATOM   6045  C C    . PRO B 1 71  ? -17.103 43.302  56.114 1.00 12.97 ?  37   PRO B C    1 
ATOM   6046  O O    . PRO B 1 71  ? -16.514 42.242  56.362 1.00 13.26 ?  37   PRO B O    1 
ATOM   6047  C CB   . PRO B 1 71  ? -16.374 44.657  58.137 1.00 13.60 ?  37   PRO B CB   1 
ATOM   6048  C CG   . PRO B 1 71  ? -16.340 43.600  59.248 1.00 14.59 ?  37   PRO B CG   1 
ATOM   6049  C CD   . PRO B 1 71  ? -17.790 43.238  59.466 1.00 13.34 ?  37   PRO B CD   1 
ATOM   6050  H HA   . PRO B 1 71  ? -17.973 45.026  56.877 1.00 13.91 ?  37   PRO B HA   1 
ATOM   6051  H HB2  . PRO B 1 71  ? -15.549 44.655  57.628 1.00 16.33 ?  37   PRO B HB2  1 
ATOM   6052  H HB3  . PRO B 1 71  ? -16.537 45.541  58.502 1.00 16.33 ?  37   PRO B HB3  1 
ATOM   6053  H HG2  . PRO B 1 71  ? -15.828 42.830  58.958 1.00 17.51 ?  37   PRO B HG2  1 
ATOM   6054  H HG3  . PRO B 1 71  ? -15.950 43.975  60.053 1.00 17.51 ?  37   PRO B HG3  1 
ATOM   6055  H HD2  . PRO B 1 71  ? -17.874 42.303  59.710 1.00 16.01 ?  37   PRO B HD2  1 
ATOM   6056  H HD3  . PRO B 1 71  ? -18.181 43.797  60.155 1.00 16.01 ?  37   PRO B HD3  1 
ATOM   6057  N N    . LEU B 1 72  ? -17.380 43.694  54.878 1.00 11.54 ?  38   LEU B N    1 
ATOM   6058  C CA   . LEU B 1 72  ? -17.236 42.788  53.740 1.00 11.41 ?  38   LEU B CA   1 
ATOM   6059  C C    . LEU B 1 72  ? -16.170 43.243  52.754 1.00 12.91 ?  38   LEU B C    1 
ATOM   6060  O O    . LEU B 1 72  ? -15.991 44.437  52.502 1.00 13.70 ?  38   LEU B O    1 
ATOM   6061  C CB   . LEU B 1 72  ? -18.548 42.701  52.969 1.00 12.83 ?  38   LEU B CB   1 
ATOM   6062  C CG   . LEU B 1 72  ? -19.746 42.164  53.764 1.00 12.77 ?  38   LEU B CG   1 
ATOM   6063  C CD1  . LEU B 1 72  ? -21.020 42.196  52.945 1.00 16.00 ?  38   LEU B CD1  1 
ATOM   6064  C CD2  . LEU B 1 72  ? -19.527 40.745  54.244 1.00 13.52 ?  38   LEU B CD2  1 
ATOM   6065  H H    . LEU B 1 72  ? -17.654 44.482  54.670 1.00 13.85 ?  38   LEU B H    1 
ATOM   6066  H HA   . LEU B 1 72  ? -16.965 41.925  54.090 1.00 13.70 ?  38   LEU B HA   1 
ATOM   6067  H HB2  . LEU B 1 72  ? -18.780 43.591  52.661 1.00 15.40 ?  38   LEU B HB2  1 
ATOM   6068  H HB3  . LEU B 1 72  ? -18.416 42.111  52.210 1.00 15.40 ?  38   LEU B HB3  1 
ATOM   6069  H HG   . LEU B 1 72  ? -19.841 42.746  54.535 1.00 15.32 ?  38   LEU B HG   1 
ATOM   6070  H HD11 . LEU B 1 72  ? -21.762 41.921  53.505 1.00 19.21 ?  38   LEU B HD11 1 
ATOM   6071  H HD12 . LEU B 1 72  ? -21.165 43.099  52.622 1.00 19.21 ?  38   LEU B HD12 1 
ATOM   6072  H HD13 . LEU B 1 72  ? -20.928 41.588  52.195 1.00 19.21 ?  38   LEU B HD13 1 
ATOM   6073  H HD21 . LEU B 1 72  ? -20.354 40.410  54.625 1.00 16.23 ?  38   LEU B HD21 1 
ATOM   6074  H HD22 . LEU B 1 72  ? -19.262 40.194  53.491 1.00 16.23 ?  38   LEU B HD22 1 
ATOM   6075  H HD23 . LEU B 1 72  ? -18.829 40.744  54.917 1.00 16.23 ?  38   LEU B HD23 1 
ATOM   6076  N N    . TYR B 1 73  ? -15.501 42.254  52.151 1.00 11.44 ?  39   TYR B N    1 
ATOM   6077  C CA   . TYR B 1 73  ? -14.490 42.425  51.122 1.00 11.51 ?  39   TYR B CA   1 
ATOM   6078  C C    . TYR B 1 73  ? -15.002 41.835  49.815 1.00 11.93 ?  39   TYR B C    1 
ATOM   6079  O O    . TYR B 1 73  ? -15.685 40.810  49.806 1.00 11.90 ?  39   TYR B O    1 
ATOM   6080  C CB   . TYR B 1 73  ? -13.244 41.617  51.538 1.00 11.40 ?  39   TYR B CB   1 
ATOM   6081  C CG   . TYR B 1 73  ? -12.066 41.563  50.578 1.00 11.72 ?  39   TYR B CG   1 
ATOM   6082  C CD1  . TYR B 1 73  ? -11.432 42.692  50.141 1.00 11.79 ?  39   TYR B CD1  1 
ATOM   6083  C CD2  . TYR B 1 73  ? -11.578 40.355  50.153 1.00 11.20 ?  39   TYR B CD2  1 
ATOM   6084  C CE1  . TYR B 1 73  ? -10.339 42.617  49.312 1.00 11.19 ?  39   TYR B CE1  1 
ATOM   6085  C CE2  . TYR B 1 73  ? -10.491 40.260  49.326 1.00 11.58 ?  39   TYR B CE2  1 
ATOM   6086  C CZ   . TYR B 1 73  ? -9.880  41.382  48.877 1.00 10.91 ?  39   TYR B CZ   1 
ATOM   6087  O OH   . TYR B 1 73  ? -8.769  41.345  48.066 1.00 11.59 ?  39   TYR B OH   1 
ATOM   6088  H H    . TYR B 1 73  ? -15.630 41.425  52.338 1.00 13.73 ?  39   TYR B H    1 
ATOM   6089  H HA   . TYR B 1 73  ? -14.277 43.363  50.992 1.00 13.81 ?  39   TYR B HA   1 
ATOM   6090  H HB2  . TYR B 1 73  ? -12.910 41.998  52.365 1.00 13.68 ?  39   TYR B HB2  1 
ATOM   6091  H HB3  . TYR B 1 73  ? -13.524 40.700  51.684 1.00 13.68 ?  39   TYR B HB3  1 
ATOM   6092  H HD1  . TYR B 1 73  ? -11.746 43.526  50.409 1.00 14.15 ?  39   TYR B HD1  1 
ATOM   6093  H HD2  . TYR B 1 73  ? -11.999 39.575  50.436 1.00 13.44 ?  39   TYR B HD2  1 
ATOM   6094  H HE1  . TYR B 1 73  ? -9.907  43.395  49.043 1.00 13.42 ?  39   TYR B HE1  1 
ATOM   6095  H HE2  . TYR B 1 73  ? -10.172 39.424  49.073 1.00 13.90 ?  39   TYR B HE2  1 
ATOM   6096  H HH   . TYR B 1 73  ? -8.380  40.605  48.145 1.00 13.91 ?  39   TYR B HH   1 
ATOM   6097  N N    . MET B 1 74  ? -14.580 42.435  48.698 1.00 12.00 ?  40   MET B N    1 
ATOM   6098  C CA   . MET B 1 74  ? -14.871 41.872  47.398 1.00 11.59 ?  40   MET B CA   1 
ATOM   6099  C C    . MET B 1 74  ? -13.590 41.752  46.596 1.00 11.09 ?  40   MET B C    1 
ATOM   6100  O O    . MET B 1 74  ? -12.719 42.602  46.690 1.00 11.95 ?  40   MET B O    1 
ATOM   6101  C CB   . MET B 1 74  ? -16.023 42.650  46.667 1.00 12.31 ?  40   MET B CB   1 
ATOM   6102  C CG   . MET B 1 74  ? -16.161 42.128  45.226 1.00 14.55 ?  40   MET B CG   1 
ATOM   6103  S SD   . MET B 1 74  ? -16.760 40.410  45.159 1.00 13.08 ?  40   MET B SD   1 
ATOM   6104  C CE   . MET B 1 74  ? -18.043 40.369  46.473 1.00 17.55 ?  40   MET B CE   1 
ATOM   6105  H H    . MET B 1 74  ? -14.125 43.165  48.678 1.00 14.40 ?  40   MET B H    1 
ATOM   6106  H HA   . MET B 1 74  ? -15.213 40.969  47.487 1.00 13.90 ?  40   MET B HA   1 
ATOM   6107  H HB2  . MET B 1 74  ? -16.862 42.508  47.134 1.00 14.77 ?  40   MET B HB2  1 
ATOM   6108  H HB3  . MET B 1 74  ? -15.814 43.597  46.640 1.00 14.77 ?  40   MET B HB3  1 
ATOM   6109  H HG2  . MET B 1 74  ? -16.794 42.686  44.747 1.00 17.46 ?  40   MET B HG2  1 
ATOM   6110  H HG3  . MET B 1 74  ? -15.294 42.162  44.793 1.00 17.46 ?  40   MET B HG3  1 
ATOM   6111  H HE1  . MET B 1 74  ? -18.457 39.492  46.482 1.00 21.06 ?  40   MET B HE1  1 
ATOM   6112  H HE2  . MET B 1 74  ? -17.623 40.545  47.329 1.00 21.06 ?  40   MET B HE2  1 
ATOM   6113  H HE3  . MET B 1 74  ? -18.709 41.048  46.285 1.00 21.06 ?  40   MET B HE3  1 
ATOM   6114  N N    . HIS B 1 75  ? -13.482 40.657  45.839 1.00 11.22 ?  41   HIS B N    1 
ATOM   6115  C CA   . HIS B 1 75  ? -12.261 40.270  45.144 1.00 11.18 ?  41   HIS B CA   1 
ATOM   6116  C C    . HIS B 1 75  ? -12.756 39.611  43.867 1.00 11.11 ?  41   HIS B C    1 
ATOM   6117  O O    . HIS B 1 75  ? -13.362 38.546  43.956 1.00 11.83 ?  41   HIS B O    1 
ATOM   6118  C CB   . HIS B 1 75  ? -11.451 39.339  46.047 1.00 10.18 ?  41   HIS B CB   1 
ATOM   6119  C CG   . HIS B 1 75  ? -10.089 39.036  45.525 1.00 10.43 ?  41   HIS B CG   1 
ATOM   6120  N ND1  . HIS B 1 75  ? -8.933  39.500  46.128 1.00 10.75 ?  41   HIS B ND1  1 
ATOM   6121  C CD2  . HIS B 1 75  ? -9.694  38.303  44.456 1.00 10.57 ?  41   HIS B CD2  1 
ATOM   6122  C CE1  . HIS B 1 75  ? -7.899  39.066  45.435 1.00 11.12 ?  41   HIS B CE1  1 
ATOM   6123  N NE2  . HIS B 1 75  ? -8.331  38.344  44.414 1.00 10.61 ?  41   HIS B NE2  1 
ATOM   6124  H H    . HIS B 1 75  ? -14.127 40.104  45.710 1.00 13.46 ?  41   HIS B H    1 
ATOM   6125  H HA   . HIS B 1 75  ? -11.682 41.010  44.906 1.00 13.42 ?  41   HIS B HA   1 
ATOM   6126  H HB2  . HIS B 1 75  ? -11.349 39.757  46.916 1.00 12.21 ?  41   HIS B HB2  1 
ATOM   6127  H HB3  . HIS B 1 75  ? -11.927 38.499  46.136 1.00 12.21 ?  41   HIS B HB3  1 
ATOM   6128  H HD2  . HIS B 1 75  ? -10.250 37.855  43.860 1.00 12.69 ?  41   HIS B HD2  1 
ATOM   6129  H HE1  . HIS B 1 75  ? -7.007  39.239  45.632 1.00 13.35 ?  41   HIS B HE1  1 
ATOM   6130  H HE2  . HIS B 1 75  ? -7.835  37.964  43.823 1.00 12.74 ?  41   HIS B HE2  1 
ATOM   6131  N N    . VAL B 1 76  ? -12.577 40.227  42.690 1.00 11.66 ?  42   VAL B N    1 
ATOM   6132  C CA   . VAL B 1 76  ? -13.434 39.875  41.552 1.00 11.23 ?  42   VAL B CA   1 
ATOM   6133  C C    . VAL B 1 76  ? -12.800 40.141  40.204 1.00 10.86 ?  42   VAL B C    1 
ATOM   6134  O O    . VAL B 1 76  ? -12.008 41.070  40.021 1.00 11.06 ?  42   VAL B O    1 
ATOM   6135  C CB   . VAL B 1 76  ? -14.776 40.649  41.680 1.00 13.72 ?  42   VAL B CB   1 
ATOM   6136  C CG1  . VAL B 1 76  ? -14.584 42.153  41.544 1.00 13.83 ?  42   VAL B CG1  1 
ATOM   6137  C CG2  . VAL B 1 76  ? -15.821 40.122  40.691 1.00 15.70 ?  42   VAL B CG2  1 
ATOM   6138  H H    . VAL B 1 76  ? -11.987 40.832  42.533 1.00 14.00 ?  42   VAL B H    1 
ATOM   6139  H HA   . VAL B 1 76  ? -13.553 38.912  41.570 1.00 13.48 ?  42   VAL B HA   1 
ATOM   6140  H HB   . VAL B 1 76  ? -15.119 40.492  42.574 1.00 16.47 ?  42   VAL B HB   1 
ATOM   6141  H HG11 . VAL B 1 76  ? -15.420 42.598  41.756 1.00 16.60 ?  42   VAL B HG11 1 
ATOM   6142  H HG12 . VAL B 1 76  ? -13.891 42.439  42.160 1.00 16.60 ?  42   VAL B HG12 1 
ATOM   6143  H HG13 . VAL B 1 76  ? -14.323 42.357  40.633 1.00 16.60 ?  42   VAL B HG13 1 
ATOM   6144  H HG21 . VAL B 1 76  ? -16.677 40.536  40.886 1.00 18.84 ?  42   VAL B HG21 1 
ATOM   6145  H HG22 . VAL B 1 76  ? -15.543 40.347  39.789 1.00 18.84 ?  42   VAL B HG22 1 
ATOM   6146  H HG23 . VAL B 1 76  ? -15.889 39.160  40.786 1.00 18.84 ?  42   VAL B HG23 1 
ATOM   6147  N N    . ARG B 1 77  ? -13.207 39.318  39.235 1.00 11.33 ?  43   ARG B N    1 
ATOM   6148  C CA   . ARG B 1 77  ? -12.991 39.541  37.810 1.00 12.46 ?  43   ARG B CA   1 
ATOM   6149  C C    . ARG B 1 77  ? -14.240 39.086  37.050 1.00 11.54 ?  43   ARG B C    1 
ATOM   6150  O O    . ARG B 1 77  ? -15.105 38.383  37.585 1.00 11.83 ?  43   ARG B O    1 
ATOM   6151  C CB   . ARG B 1 77  ? -11.714 38.849  37.288 1.00 12.08 ?  43   ARG B CB   1 
ATOM   6152  C CG   . ARG B 1 77  ? -11.813 37.351  37.336 1.00 11.71 ?  43   ARG B CG   1 
ATOM   6153  C CD   . ARG B 1 77  ? -10.551 36.691  36.870 1.00 12.28 ?  43   ARG B CD   1 
ATOM   6154  N NE   . ARG B 1 77  ? -10.608 35.238  36.944 1.00 13.25 ?  43   ARG B NE   1 
ATOM   6155  C CZ   . ARG B 1 77  ? -11.013 34.425  35.988 1.00 12.63 ?  43   ARG B CZ   1 
ATOM   6156  N NH1  . ARG B 1 77  ? -11.418 34.867  34.817 1.00 13.04 ?  43   ARG B NH1  1 
ATOM   6157  N NH2  . ARG B 1 77  ? -10.931 33.105  36.206 1.00 14.14 ?  43   ARG B NH2  1 
ATOM   6158  H H    . ARG B 1 77  ? -13.632 38.587  39.389 1.00 13.59 ?  43   ARG B H    1 
ATOM   6159  H HA   . ARG B 1 77  ? -12.872 40.488  37.641 1.00 14.95 ?  43   ARG B HA   1 
ATOM   6160  H HB2  . ARG B 1 77  ? -11.564 39.113  36.367 1.00 14.50 ?  43   ARG B HB2  1 
ATOM   6161  H HB3  . ARG B 1 77  ? -10.961 39.119  37.837 1.00 14.50 ?  43   ARG B HB3  1 
ATOM   6162  H HG2  . ARG B 1 77  ? -11.983 37.071  38.249 1.00 14.05 ?  43   ARG B HG2  1 
ATOM   6163  H HG3  . ARG B 1 77  ? -12.538 37.061  36.760 1.00 14.05 ?  43   ARG B HG3  1 
ATOM   6164  H HD2  . ARG B 1 77  ? -10.389 36.937  35.945 1.00 14.73 ?  43   ARG B HD2  1 
ATOM   6165  H HD3  . ARG B 1 77  ? -9.814  36.990  37.426 1.00 14.73 ?  43   ARG B HD3  1 
ATOM   6166  H HE   . ARG B 1 77  ? -10.354 34.875  37.682 1.00 15.90 ?  43   ARG B HE   1 
ATOM   6167  H HH11 . ARG B 1 77  ? -11.425 35.711  34.655 1.00 15.65 ?  43   ARG B HH11 1 
ATOM   6168  H HH12 . ARG B 1 77  ? -11.676 34.311  34.213 1.00 15.65 ?  43   ARG B HH12 1 
ATOM   6169  H HH21 . ARG B 1 77  ? -10.622 32.811  36.952 1.00 16.97 ?  43   ARG B HH21 1 
ATOM   6170  H HH22 . ARG B 1 77  ? -11.188 32.552  35.599 1.00 16.97 ?  43   ARG B HH22 1 
ATOM   6171  N N    . LYS B 1 78  ? -14.307 39.555  35.801 1.00 12.59 ?  44   LYS B N    1 
ATOM   6172  C CA   . LYS B 1 78  ? -15.334 39.196  34.822 1.00 11.30 ?  44   LYS B CA   1 
ATOM   6173  C C    . LYS B 1 78  ? -14.703 39.411  33.463 1.00 12.10 ?  44   LYS B C    1 
ATOM   6174  O O    . LYS B 1 78  ? -13.886 40.298  33.295 1.00 12.37 ?  44   LYS B O    1 
ATOM   6175  C CB   . LYS B 1 78  ? -16.543 40.136  35.008 1.00 12.42 ?  44   LYS B CB   1 
ATOM   6176  C CG   . LYS B 1 78  ? -17.774 39.682  34.224 1.00 13.49 ?  44   LYS B CG   1 
ATOM   6177  C CD   . LYS B 1 78  ? -18.948 40.648  34.361 1.00 13.77 ?  44   LYS B CD   1 
ATOM   6178  C CE   . LYS B 1 78  ? -20.029 40.255  33.401 1.00 12.92 ?  44   LYS B CE   1 
ATOM   6179  N NZ   . LYS B 1 78  ? -21.105 41.318  33.364 1.00 14.17 ?  44   LYS B NZ   1 
ATOM   6180  H H    . LYS B 1 78  ? -13.738 40.114  35.479 1.00 15.11 ?  44   LYS B H    1 
ATOM   6181  H HA   . LYS B 1 78  ? -15.633 38.277  34.899 1.00 13.57 ?  44   LYS B HA   1 
ATOM   6182  H HB2  . LYS B 1 78  ? -16.779 40.164  35.948 1.00 14.90 ?  44   LYS B HB2  1 
ATOM   6183  H HB3  . LYS B 1 78  ? -16.302 41.024  34.700 1.00 14.90 ?  44   LYS B HB3  1 
ATOM   6184  H HG2  . LYS B 1 78  ? -17.546 39.619  33.284 1.00 16.19 ?  44   LYS B HG2  1 
ATOM   6185  H HG3  . LYS B 1 78  ? -18.059 38.816  34.556 1.00 16.19 ?  44   LYS B HG3  1 
ATOM   6186  H HD2  . LYS B 1 78  ? -19.301 40.613  35.264 1.00 16.52 ?  44   LYS B HD2  1 
ATOM   6187  H HD3  . LYS B 1 78  ? -18.657 41.550  34.154 1.00 16.52 ?  44   LYS B HD3  1 
ATOM   6188  H HE2  . LYS B 1 78  ? -19.656 40.159  32.511 1.00 15.50 ?  44   LYS B HE2  1 
ATOM   6189  H HE3  . LYS B 1 78  ? -20.429 39.418  33.686 1.00 15.50 ?  44   LYS B HE3  1 
ATOM   6190  H HZ1  . LYS B 1 78  ? -21.815 41.018  32.918 1.00 17.01 ?  44   LYS B HZ1  1 
ATOM   6191  H HZ2  . LYS B 1 78  ? -21.353 41.530  34.192 1.00 17.01 ?  44   LYS B HZ2  1 
ATOM   6192  H HZ3  . LYS B 1 78  ? -20.798 42.049  32.959 1.00 17.01 ?  44   LYS B HZ3  1 
ATOM   6193  N N    . ASN B 1 79  ? -15.033 38.556  32.486 1.00 12.32 ?  45   ASN B N    1 
ATOM   6194  C CA   . ASN B 1 79  ? -14.354 38.691  31.197 1.00 11.15 ?  45   ASN B CA   1 
ATOM   6195  C C    . ASN B 1 79  ? -14.845 39.877  30.371 1.00 12.08 ?  45   ASN B C    1 
ATOM   6196  O O    . ASN B 1 79  ? -14.153 40.293  29.439 1.00 13.02 ?  45   ASN B O    1 
ATOM   6197  C CB   . ASN B 1 79  ? -14.472 37.391  30.371 1.00 13.07 ?  45   ASN B CB   1 
ATOM   6198  C CG   . ASN B 1 79  ? -13.699 36.263  30.985 1.00 14.38 ?  45   ASN B CG   1 
ATOM   6199  O OD1  . ASN B 1 79  ? -12.504 36.351  31.163 1.00 14.77 ?  45   ASN B OD1  1 
ATOM   6200  N ND2  . ASN B 1 79  ? -14.399 35.214  31.353 1.00 15.26 ?  45   ASN B ND2  1 
ATOM   6201  H H    . ASN B 1 79  ? -15.614 37.925  32.545 1.00 14.79 ?  45   ASN B H    1 
ATOM   6202  H HA   . ASN B 1 79  ? -13.412 38.835  31.377 1.00 13.38 ?  45   ASN B HA   1 
ATOM   6203  H HB2  . ASN B 1 79  ? -15.404 37.128  30.322 1.00 15.69 ?  45   ASN B HB2  1 
ATOM   6204  H HB3  . ASN B 1 79  ? -14.124 37.547  29.480 1.00 15.69 ?  45   ASN B HB3  1 
ATOM   6205  H HD21 . ASN B 1 79  ? -14.005 34.538  31.710 1.00 18.31 ?  45   ASN B HD21 1 
ATOM   6206  H HD22 . ASN B 1 79  ? -15.251 35.203  31.236 1.00 18.31 ?  45   ASN B HD22 1 
ATOM   6207  N N    . THR B 1 80  ? -16.037 40.376  30.679 1.00 11.98 ?  46   THR B N    1 
ATOM   6208  C CA   . THR B 1 80  ? -16.642 41.532  30.001 1.00 11.77 ?  46   THR B CA   1 
ATOM   6209  C C    . THR B 1 80  ? -17.079 42.520  31.069 1.00 15.06 ?  46   THR B C    1 
ATOM   6210  O O    . THR B 1 80  ? -17.019 42.246  32.270 1.00 14.77 ?  46   THR B O    1 
ATOM   6211  C CB   . THR B 1 80  ? -17.835 41.081  29.163 1.00 14.15 ?  46   THR B CB   1 
ATOM   6212  O OG1  . THR B 1 80  ? -18.739 40.401  30.011 1.00 16.26 ?  46   THR B OG1  1 
ATOM   6213  C CG2  . THR B 1 80  ? -17.409 40.149  28.000 1.00 14.99 ?  46   THR B CG2  1 
ATOM   6214  H H    . THR B 1 80  ? -16.538 40.055  31.299 1.00 14.38 ?  46   THR B H    1 
ATOM   6215  H HA   . THR B 1 80  ? -16.005 41.970  29.416 1.00 14.13 ?  46   THR B HA   1 
ATOM   6216  H HB   . THR B 1 80  ? -18.259 41.854  28.760 1.00 16.98 ?  46   THR B HB   1 
ATOM   6217  H HG1  . THR B 1 80  ? -19.355 40.056  29.557 1.00 19.51 ?  46   THR B HG1  1 
ATOM   6218  H HG21 . THR B 1 80  ? -18.168 39.971  27.423 1.00 17.99 ?  46   THR B HG21 1 
ATOM   6219  H HG22 . THR B 1 80  ? -16.708 40.569  27.478 1.00 17.99 ?  46   THR B HG22 1 
ATOM   6220  H HG23 . THR B 1 80  ? -17.078 39.308  28.353 1.00 17.99 ?  46   THR B HG23 1 
ATOM   6221  N N    . ALA B 1 81  ? -17.518 43.702  30.613 1.00 13.29 ?  47   ALA B N    1 
ATOM   6222  C CA   . ALA B 1 81  ? -17.886 44.764  31.525 1.00 12.85 ?  47   ALA B CA   1 
ATOM   6223  C C    . ALA B 1 81  ? -18.972 44.316  32.501 1.00 13.72 ?  47   ALA B C    1 
ATOM   6224  O O    . ALA B 1 81  ? -19.886 43.553  32.170 1.00 13.20 ?  47   ALA B O    1 
ATOM   6225  C CB   . ALA B 1 81  ? -18.433 45.938  30.709 1.00 14.00 ?  47   ALA B CB   1 
ATOM   6226  H H    . ALA B 1 81  ? -17.608 43.902  29.782 1.00 15.95 ?  47   ALA B H    1 
ATOM   6227  H HA   . ALA B 1 81  ? -17.106 45.029  32.038 1.00 15.42 ?  47   ALA B HA   1 
ATOM   6228  H HB1  . ALA B 1 81  ? -18.697 46.648  31.314 1.00 16.80 ?  47   ALA B HB1  1 
ATOM   6229  H HB2  . ALA B 1 81  ? -17.741 46.256  30.108 1.00 16.80 ?  47   ALA B HB2  1 
ATOM   6230  H HB3  . ALA B 1 81  ? -19.201 45.637  30.198 1.00 16.80 ?  47   ALA B HB3  1 
ATOM   6231  N N    . TYR B 1 82  ? -18.876 44.858  33.724 1.00 13.39 ?  48   TYR B N    1 
ATOM   6232  C CA   . TYR B 1 82  ? -19.945 44.695  34.696 1.00 12.85 ?  48   TYR B CA   1 
ATOM   6233  C C    . TYR B 1 82  ? -21.213 45.417  34.220 1.00 14.86 ?  48   TYR B C    1 
ATOM   6234  O O    . TYR B 1 82  ? -21.134 46.491  33.592 1.00 15.51 ?  48   TYR B O    1 
ATOM   6235  C CB   . TYR B 1 82  ? -19.501 45.205  36.079 1.00 13.13 ?  48   TYR B CB   1 
ATOM   6236  C CG   . TYR B 1 82  ? -18.310 44.425  36.606 1.00 11.64 ?  48   TYR B CG   1 
ATOM   6237  C CD1  . TYR B 1 82  ? -18.494 43.212  37.229 1.00 12.67 ?  48   TYR B CD1  1 
ATOM   6238  C CD2  . TYR B 1 82  ? -17.034 44.881  36.438 1.00 12.99 ?  48   TYR B CD2  1 
ATOM   6239  C CE1  . TYR B 1 82  ? -17.403 42.467  37.668 1.00 12.12 ?  48   TYR B CE1  1 
ATOM   6240  C CE2  . TYR B 1 82  ? -15.941 44.162  36.868 1.00 11.83 ?  48   TYR B CE2  1 
ATOM   6241  C CZ   . TYR B 1 82  ? -16.158 42.928  37.463 1.00 11.68 ?  48   TYR B CZ   1 
ATOM   6242  O OH   . TYR B 1 82  ? -15.064 42.182  37.924 1.00 12.88 ?  48   TYR B OH   1 
ATOM   6243  H H    . TYR B 1 82  ? -18.205 45.317  34.005 1.00 16.07 ?  48   TYR B H    1 
ATOM   6244  H HA   . TYR B 1 82  ? -20.162 43.755  34.795 1.00 15.42 ?  48   TYR B HA   1 
ATOM   6245  H HB2  . TYR B 1 82  ? -19.248 46.139  36.010 1.00 15.76 ?  48   TYR B HB2  1 
ATOM   6246  H HB3  . TYR B 1 82  ? -20.233 45.106  36.708 1.00 15.76 ?  48   TYR B HB3  1 
ATOM   6247  H HD1  . TYR B 1 82  ? -19.356 42.886  37.359 1.00 15.21 ?  48   TYR B HD1  1 
ATOM   6248  H HD2  . TYR B 1 82  ? -16.899 45.701  36.021 1.00 15.59 ?  48   TYR B HD2  1 
ATOM   6249  H HE1  . TYR B 1 82  ? -17.535 41.655  38.101 1.00 14.55 ?  48   TYR B HE1  1 
ATOM   6250  H HE2  . TYR B 1 82  ? -15.079 44.496  36.763 1.00 14.20 ?  48   TYR B HE2  1 
ATOM   6251  H HH   . TYR B 1 82  ? -14.346 42.543  37.680 1.00 15.46 ?  48   TYR B HH   1 
ATOM   6252  N N    . THR B 1 83  ? -22.362 44.845  34.543 1.00 13.39 ?  49   THR B N    1 
ATOM   6253  C CA   . THR B 1 83  ? -23.602 45.567  34.294 1.00 14.79 ?  49   THR B CA   1 
ATOM   6254  C C    . THR B 1 83  ? -23.753 46.683  35.329 1.00 16.29 ?  49   THR B C    1 
ATOM   6255  O O    . THR B 1 83  ? -23.028 46.770  36.328 1.00 14.43 ?  49   THR B O    1 
ATOM   6256  C CB   . THR B 1 83  ? -24.778 44.635  34.455 1.00 14.06 ?  49   THR B CB   1 
ATOM   6257  O OG1  . THR B 1 83  ? -24.869 44.283  35.839 1.00 15.25 ?  49   THR B OG1  1 
ATOM   6258  C CG2  . THR B 1 83  ? -24.679 43.388  33.599 1.00 14.79 ?  49   THR B CG2  1 
ATOM   6259  H H    . THR B 1 83  ? -22.450 44.065  34.896 1.00 16.07 ?  49   THR B H    1 
ATOM   6260  H HA   . THR B 1 83  ? -23.589 45.934  33.396 1.00 17.74 ?  49   THR B HA   1 
ATOM   6261  H HB   . THR B 1 83  ? -25.584 45.083  34.155 1.00 16.87 ?  49   THR B HB   1 
ATOM   6262  H HG1  . THR B 1 83  ? -25.434 43.671  35.943 1.00 18.30 ?  49   THR B HG1  1 
ATOM   6263  H HG21 . THR B 1 83  ? -25.495 42.869  33.674 1.00 17.75 ?  49   THR B HG21 1 
ATOM   6264  H HG22 . THR B 1 83  ? -24.546 43.633  32.670 1.00 17.75 ?  49   THR B HG22 1 
ATOM   6265  H HG23 . THR B 1 83  ? -23.932 42.843  33.891 1.00 17.75 ?  49   THR B HG23 1 
ATOM   6266  N N    . ASP B 1 84  ? -24.717 47.592  35.096 1.00 16.44 ?  50   ASP B N    1 
ATOM   6267  C CA   A ASP B 1 84  ? -24.986 48.631  36.086 0.66 14.58 ?  50   ASP B CA   1 
ATOM   6268  C CA   B ASP B 1 84  ? -24.983 48.636  36.085 0.34 14.74 ?  50   ASP B CA   1 
ATOM   6269  C C    . ASP B 1 84  ? -25.292 48.046  37.464 1.00 14.86 ?  50   ASP B C    1 
ATOM   6270  O O    . ASP B 1 84  ? -24.813 48.545  38.493 1.00 15.22 ?  50   ASP B O    1 
ATOM   6271  C CB   A ASP B 1 84  ? -26.205 49.446  35.663 0.66 17.60 ?  50   ASP B CB   1 
ATOM   6272  C CB   B ASP B 1 84  ? -26.144 49.519  35.616 0.34 17.53 ?  50   ASP B CB   1 
ATOM   6273  C CG   A ASP B 1 84  ? -25.959 50.308  34.464 0.66 22.34 ?  50   ASP B CG   1 
ATOM   6274  C CG   B ASP B 1 84  ? -26.383 50.722  36.528 0.34 22.35 ?  50   ASP B CG   1 
ATOM   6275  O OD1  A ASP B 1 84  ? -24.833 50.359  33.940 0.66 20.48 ?  50   ASP B OD1  1 
ATOM   6276  O OD1  B ASP B 1 84  ? -25.601 50.930  37.483 0.34 41.77 ?  50   ASP B OD1  1 
ATOM   6277  O OD2  A ASP B 1 84  ? -26.950 50.950  34.042 0.66 27.78 ?  50   ASP B OD2  1 
ATOM   6278  O OD2  B ASP B 1 84  ? -27.374 51.448  36.301 0.34 38.81 ?  50   ASP B OD2  1 
ATOM   6279  H H    . ASP B 1 84  ? -25.213 47.624  34.394 1.00 19.73 ?  50   ASP B H    1 
ATOM   6280  H HA   . ASP B 1 84  ? -24.196 49.192  36.136 1.00 17.69 ?  50   ASP B HA   1 
ATOM   6281  H HB2  A ASP B 1 84  ? -26.929 48.837  35.447 0.66 21.12 ?  50   ASP B HB2  1 
ATOM   6282  H HB2  B ASP B 1 84  ? -25.947 49.852  34.727 0.34 21.03 ?  50   ASP B HB2  1 
ATOM   6283  H HB3  A ASP B 1 84  ? -26.466 50.024  36.396 0.66 21.12 ?  50   ASP B HB3  1 
ATOM   6284  H HB3  B ASP B 1 84  ? -26.956 48.989  35.600 0.34 21.03 ?  50   ASP B HB3  1 
ATOM   6285  N N    . GLU B 1 85  ? -26.122 46.999  37.519 1.00 15.09 ?  51   GLU B N    1 
ATOM   6286  C CA   . GLU B 1 85  ? -26.445 46.355  38.782 1.00 15.65 ?  51   GLU B CA   1 
ATOM   6287  C C    . GLU B 1 85  ? -25.176 45.838  39.459 1.00 15.45 ?  51   GLU B C    1 
ATOM   6288  O O    . GLU B 1 85  ? -25.031 45.958  40.679 1.00 15.98 ?  51   GLU B O    1 
ATOM   6289  C CB   . GLU B 1 85  ? -27.414 45.204  38.558 1.00 18.00 ?  51   GLU B CB   1 
ATOM   6290  C CG   . GLU B 1 85  ? -27.651 44.362  39.805 1.00 22.44 ?  51   GLU B CG   1 
ATOM   6291  C CD   . GLU B 1 85  ? -28.506 43.115  39.565 1.00 25.99 ?  51   GLU B CD   1 
ATOM   6292  O OE1  . GLU B 1 85  ? -28.543 42.589  38.432 1.00 24.81 ?  51   GLU B OE1  1 
ATOM   6293  O OE2  . GLU B 1 85  ? -29.093 42.631  40.556 1.00 30.51 ?  51   GLU B OE2  1 
ATOM   6294  H H    . GLU B 1 85  ? -26.508 46.646  36.837 1.00 18.11 ?  51   GLU B H    1 
ATOM   6295  H HA   . GLU B 1 85  ? -26.876 47.002  39.363 1.00 18.79 ?  51   GLU B HA   1 
ATOM   6296  H HB2  . GLU B 1 85  ? -28.269 45.564  38.275 1.00 21.60 ?  51   GLU B HB2  1 
ATOM   6297  H HB3  . GLU B 1 85  ? -27.055 44.622  37.870 1.00 21.60 ?  51   GLU B HB3  1 
ATOM   6298  H HG2  . GLU B 1 85  ? -26.793 44.069  40.150 1.00 26.92 ?  51   GLU B HG2  1 
ATOM   6299  H HG3  . GLU B 1 85  ? -28.105 44.908  40.467 1.00 26.92 ?  51   GLU B HG3  1 
ATOM   6300  N N    . GLU B 1 86  ? -24.251 45.262  38.665 1.00 13.69 ?  52   GLU B N    1 
ATOM   6301  C CA   . GLU B 1 86  ? -23.023 44.725  39.230 1.00 11.56 ?  52   GLU B CA   1 
ATOM   6302  C C    . GLU B 1 86  ? -22.117 45.831  39.728 1.00 14.14 ?  52   GLU B C    1 
ATOM   6303  O O    . GLU B 1 86  ? -21.479 45.679  40.775 1.00 13.51 ?  52   GLU B O    1 
ATOM   6304  C CB   . GLU B 1 86  ? -22.363 43.866  38.158 1.00 14.29 ?  52   GLU B CB   1 
ATOM   6305  C CG   . GLU B 1 86  ? -23.082 42.515  37.936 1.00 15.31 ?  52   GLU B CG   1 
ATOM   6306  C CD   . GLU B 1 86  ? -22.580 41.726  36.767 1.00 14.28 ?  52   GLU B CD   1 
ATOM   6307  O OE1  . GLU B 1 86  ? -21.969 42.275  35.841 1.00 14.74 ?  52   GLU B OE1  1 
ATOM   6308  O OE2  . GLU B 1 86  ? -22.855 40.495  36.768 1.00 18.40 ?  52   GLU B OE2  1 
ATOM   6309  H H    . GLU B 1 86  ? -24.318 45.177  37.812 1.00 16.43 ?  52   GLU B H    1 
ATOM   6310  H HA   . GLU B 1 86  ? -23.207 44.166  40.002 1.00 13.87 ?  52   GLU B HA   1 
ATOM   6311  H HB2  . GLU B 1 86  ? -22.370 44.351  37.318 1.00 17.14 ?  52   GLU B HB2  1 
ATOM   6312  H HB3  . GLU B 1 86  ? -21.449 43.678  38.424 1.00 17.14 ?  52   GLU B HB3  1 
ATOM   6313  H HG2  . GLU B 1 86  ? -22.965 41.969  38.729 1.00 18.37 ?  52   GLU B HG2  1 
ATOM   6314  H HG3  . GLU B 1 86  ? -24.025 42.689  37.789 1.00 18.37 ?  52   GLU B HG3  1 
ATOM   6315  N N    . ILE B 1 87  ? -22.033 46.966  39.007 1.00 12.94 ?  53   ILE B N    1 
ATOM   6316  C CA   . ILE B 1 87  ? -21.262 48.096  39.506 1.00 12.89 ?  53   ILE B CA   1 
ATOM   6317  C C    . ILE B 1 87  ? -21.829 48.591  40.831 1.00 13.35 ?  53   ILE B C    1 
ATOM   6318  O O    . ILE B 1 87  ? -21.066 48.887  41.767 1.00 14.22 ?  53   ILE B O    1 
ATOM   6319  C CB   . ILE B 1 87  ? -21.215 49.236  38.466 1.00 12.37 ?  53   ILE B CB   1 
ATOM   6320  C CG1  . ILE B 1 87  ? -20.378 48.855  37.250 1.00 14.18 ?  53   ILE B CG1  1 
ATOM   6321  C CG2  . ILE B 1 87  ? -20.708 50.536  39.092 1.00 15.71 ?  53   ILE B CG2  1 
ATOM   6322  C CD1  . ILE B 1 87  ? -18.915 48.568  37.548 1.00 14.10 ?  53   ILE B CD1  1 
ATOM   6323  H H    . ILE B 1 87  ? -22.409 47.095  38.244 1.00 15.53 ?  53   ILE B H    1 
ATOM   6324  H HA   . ILE B 1 87  ? -20.355 47.789  39.657 1.00 15.47 ?  53   ILE B HA   1 
ATOM   6325  H HB   . ILE B 1 87  ? -22.124 49.380  38.161 1.00 14.85 ?  53   ILE B HB   1 
ATOM   6326  H HG12 . ILE B 1 87  ? -20.757 48.055  36.853 1.00 17.02 ?  53   ILE B HG12 1 
ATOM   6327  H HG13 . ILE B 1 87  ? -20.408 49.587  36.614 1.00 17.02 ?  53   ILE B HG13 1 
ATOM   6328  H HG21 . ILE B 1 87  ? -20.497 51.166  38.385 1.00 18.85 ?  53   ILE B HG21 1 
ATOM   6329  H HG22 . ILE B 1 87  ? -21.400 50.901  39.665 1.00 18.85 ?  53   ILE B HG22 1 
ATOM   6330  H HG23 . ILE B 1 87  ? -19.912 50.347  39.613 1.00 18.85 ?  53   ILE B HG23 1 
ATOM   6331  H HD11 . ILE B 1 87  ? -18.444 48.426  36.712 1.00 16.92 ?  53   ILE B HD11 1 
ATOM   6332  H HD12 . ILE B 1 87  ? -18.534 49.326  38.018 1.00 16.92 ?  53   ILE B HD12 1 
ATOM   6333  H HD13 . ILE B 1 87  ? -18.856 47.772  38.099 1.00 16.92 ?  53   ILE B HD13 1 
ATOM   6334  N N    . ASN B 1 88  ? -23.156 48.658  40.952 1.00 14.61 ?  54   ASN B N    1 
ATOM   6335  C CA   . ASN B 1 88  ? -23.729 49.075  42.225 1.00 16.36 ?  54   ASN B CA   1 
ATOM   6336  C C    . ASN B 1 88  ? -23.386 48.102  43.335 1.00 15.00 ?  54   ASN B C    1 
ATOM   6337  O O    . ASN B 1 88  ? -23.108 48.513  44.466 1.00 15.61 ?  54   ASN B O    1 
ATOM   6338  C CB   . ASN B 1 88  ? -25.251 49.195  42.095 1.00 18.49 ?  54   ASN B CB   1 
ATOM   6339  C CG   . ASN B 1 88  ? -25.676 50.311  41.182 1.00 20.91 ?  54   ASN B CG   1 
ATOM   6340  O OD1  . ASN B 1 88  ? -24.910 51.200  40.892 1.00 22.85 ?  54   ASN B OD1  1 
ATOM   6341  N ND2  . ASN B 1 88  ? -26.899 50.231  40.717 1.00 23.90 ?  54   ASN B ND2  1 
ATOM   6342  H H    . ASN B 1 88  ? -23.724 48.474  40.333 1.00 17.53 ?  54   ASN B H    1 
ATOM   6343  H HA   . ASN B 1 88  ? -23.363 49.943  42.456 1.00 19.63 ?  54   ASN B HA   1 
ATOM   6344  H HB2  . ASN B 1 88  ? -25.604 48.365  41.737 1.00 22.19 ?  54   ASN B HB2  1 
ATOM   6345  H HB3  . ASN B 1 88  ? -25.630 49.366  42.972 1.00 22.19 ?  54   ASN B HB3  1 
ATOM   6346  H HD21 . ASN B 1 88  ? -27.199 50.840  40.189 1.00 28.68 ?  54   ASN B HD21 1 
ATOM   6347  H HD22 . ASN B 1 88  ? -27.401 49.569  40.939 1.00 28.68 ?  54   ASN B HD22 1 
ATOM   6348  N N    . TYR B 1 89  ? -23.395 46.808  43.021 1.00 13.90 ?  55   TYR B N    1 
ATOM   6349  C CA   . TYR B 1 89  ? -23.000 45.806  44.007 1.00 13.14 ?  55   TYR B CA   1 
ATOM   6350  C C    . TYR B 1 89  ? -21.553 46.006  44.427 1.00 13.42 ?  55   TYR B C    1 
ATOM   6351  O O    . TYR B 1 89  ? -21.256 46.098  45.618 1.00 13.84 ?  55   TYR B O    1 
ATOM   6352  C CB   . TYR B 1 89  ? -23.216 44.452  43.378 1.00 13.23 ?  55   TYR B CB   1 
ATOM   6353  C CG   . TYR B 1 89  ? -22.883 43.260  44.254 1.00 15.45 ?  55   TYR B CG   1 
ATOM   6354  C CD1  . TYR B 1 89  ? -23.612 42.981  45.403 1.00 15.08 ?  55   TYR B CD1  1 
ATOM   6355  C CD2  . TYR B 1 89  ? -21.844 42.392  43.908 1.00 15.63 ?  55   TYR B CD2  1 
ATOM   6356  C CE1  . TYR B 1 89  ? -23.300 41.851  46.191 1.00 16.25 ?  55   TYR B CE1  1 
ATOM   6357  C CE2  . TYR B 1 89  ? -21.563 41.283  44.667 1.00 14.56 ?  55   TYR B CE2  1 
ATOM   6358  C CZ   . TYR B 1 89  ? -22.285 41.021  45.786 1.00 15.81 ?  55   TYR B CZ   1 
ATOM   6359  O OH   . TYR B 1 89  ? -21.946 39.894  46.539 1.00 18.95 ?  55   TYR B OH   1 
ATOM   6360  H H    . TYR B 1 89  ? -23.623 46.488  42.256 1.00 16.68 ?  55   TYR B H    1 
ATOM   6361  H HA   . TYR B 1 89  ? -23.537 45.873  44.812 1.00 15.77 ?  55   TYR B HA   1 
ATOM   6362  H HB2  . TYR B 1 89  ? -24.151 44.376  43.132 1.00 15.87 ?  55   TYR B HB2  1 
ATOM   6363  H HB3  . TYR B 1 89  ? -22.659 44.392  42.586 1.00 15.87 ?  55   TYR B HB3  1 
ATOM   6364  H HD1  . TYR B 1 89  ? -24.310 43.542  45.655 1.00 18.09 ?  55   TYR B HD1  1 
ATOM   6365  H HD2  . TYR B 1 89  ? -21.334 42.568  43.150 1.00 18.76 ?  55   TYR B HD2  1 
ATOM   6366  H HE1  . TYR B 1 89  ? -23.775 41.673  46.970 1.00 19.50 ?  55   TYR B HE1  1 
ATOM   6367  H HE2  . TYR B 1 89  ? -20.876 40.709  44.413 1.00 17.47 ?  55   TYR B HE2  1 
ATOM   6368  H HH   . TYR B 1 89  ? -21.230 39.562  46.252 1.00 22.74 ?  55   TYR B HH   1 
ATOM   6369  N N    . LEU B 1 90  ? -20.639 46.156  43.465 1.00 12.06 ?  56   LEU B N    1 
ATOM   6370  C CA   . LEU B 1 90  ? -19.254 46.396  43.830 1.00 12.46 ?  56   LEU B CA   1 
ATOM   6371  C C    . LEU B 1 90  ? -19.099 47.632  44.686 1.00 13.42 ?  56   LEU B C    1 
ATOM   6372  O O    . LEU B 1 90  ? -18.333 47.645  45.659 1.00 13.49 ?  56   LEU B O    1 
ATOM   6373  C CB   . LEU B 1 90  ? -18.382 46.492  42.582 1.00 13.96 ?  56   LEU B CB   1 
ATOM   6374  C CG   . LEU B 1 90  ? -18.297 45.224  41.752 1.00 12.15 ?  56   LEU B CG   1 
ATOM   6375  C CD1  . LEU B 1 90  ? -17.407 45.453  40.541 1.00 15.40 ?  56   LEU B CD1  1 
ATOM   6376  C CD2  . LEU B 1 90  ? -17.799 44.035  42.596 1.00 14.53 ?  56   LEU B CD2  1 
ATOM   6377  H H    . LEU B 1 90  ? -20.796 46.123  42.620 1.00 14.47 ?  56   LEU B H    1 
ATOM   6378  H HA   . LEU B 1 90  ? -18.946 45.639  44.352 1.00 14.95 ?  56   LEU B HA   1 
ATOM   6379  H HB2  . LEU B 1 90  ? -18.742 47.190  42.011 1.00 16.75 ?  56   LEU B HB2  1 
ATOM   6380  H HB3  . LEU B 1 90  ? -17.480 46.721  42.856 1.00 16.75 ?  56   LEU B HB3  1 
ATOM   6381  H HG   . LEU B 1 90  ? -19.184 44.991  41.435 1.00 14.58 ?  56   LEU B HG   1 
ATOM   6382  H HD11 . LEU B 1 90  ? -17.468 44.684  39.954 1.00 18.48 ?  56   LEU B HD11 1 
ATOM   6383  H HD12 . LEU B 1 90  ? -17.706 46.250  40.076 1.00 18.48 ?  56   LEU B HD12 1 
ATOM   6384  H HD13 . LEU B 1 90  ? -16.491 45.569  40.840 1.00 18.48 ?  56   LEU B HD13 1 
ATOM   6385  H HD21 . LEU B 1 90  ? -17.740 43.249  42.031 1.00 17.44 ?  56   LEU B HD21 1 
ATOM   6386  H HD22 . LEU B 1 90  ? -16.925 44.249  42.958 1.00 17.44 ?  56   LEU B HD22 1 
ATOM   6387  H HD23 . LEU B 1 90  ? -18.426 43.877  43.319 1.00 17.44 ?  56   LEU B HD23 1 
ATOM   6388  N N    . ALA B 1 91  ? -19.783 48.719  44.301 1.00 13.41 ?  57   ALA B N    1 
ATOM   6389  C CA   . ALA B 1 91  ? -19.645 49.981  44.990 1.00 13.64 ?  57   ALA B CA   1 
ATOM   6390  C C    . ALA B 1 91  ? -20.154 49.924  46.422 1.00 13.62 ?  57   ALA B C    1 
ATOM   6391  O O    . ALA B 1 91  ? -19.853 50.836  47.208 1.00 15.74 ?  57   ALA B O    1 
ATOM   6392  C CB   . ALA B 1 91  ? -20.377 51.059  44.206 1.00 14.88 ?  57   ALA B CB   1 
ATOM   6393  H H    . ALA B 1 91  ? -20.333 48.739  43.640 1.00 16.09 ?  57   ALA B H    1 
ATOM   6394  H HA   . ALA B 1 91  ? -18.706 50.222  45.035 1.00 16.37 ?  57   ALA B HA   1 
ATOM   6395  H HB1  . ALA B 1 91  ? -20.270 51.909  44.662 1.00 17.86 ?  57   ALA B HB1  1 
ATOM   6396  H HB2  . ALA B 1 91  ? -19.999 51.113  43.315 1.00 17.86 ?  57   ALA B HB2  1 
ATOM   6397  H HB3  . ALA B 1 91  ? -21.317 50.828  44.154 1.00 17.86 ?  57   ALA B HB3  1 
ATOM   6398  N N    . SER B 1 92  ? -20.915 48.907  46.783 1.00 13.53 ?  58   SER B N    1 
ATOM   6399  C CA   . SER B 1 92  ? -21.430 48.783  48.141 1.00 13.95 ?  58   SER B CA   1 
ATOM   6400  C C    . SER B 1 92  ? -20.428 48.166  49.110 1.00 14.24 ?  58   SER B C    1 
ATOM   6401  O O    . SER B 1 92  ? -20.713 48.103  50.316 1.00 16.87 ?  58   SER B O    1 
ATOM   6402  C CB   . SER B 1 92  ? -22.687 47.930  48.171 1.00 16.25 ?  58   SER B CB   1 
ATOM   6403  O OG   . SER B 1 92  ? -22.439 46.534  47.987 1.00 16.41 ?  58   SER B OG   1 
ATOM   6404  H H    . SER B 1 92  ? -21.152 48.268  46.258 1.00 16.24 ?  58   SER B H    1 
ATOM   6405  H HA   . SER B 1 92  ? -21.654 49.677  48.443 1.00 16.74 ?  58   SER B HA   1 
ATOM   6406  H HB2  . SER B 1 92  ? -23.117 48.052  49.032 1.00 19.50 ?  58   SER B HB2  1 
ATOM   6407  H HB3  . SER B 1 92  ? -23.276 48.231  47.461 1.00 19.50 ?  58   SER B HB3  1 
ATOM   6408  H HG   . SER B 1 92  ? -22.020 46.409  47.271 1.00 19.69 ?  58   SER B HG   1 
ATOM   6409  N N    . PHE B 1 93  ? -19.277 47.693  48.609 1.00 13.60 ?  59   PHE B N    1 
ATOM   6410  C CA   . PHE B 1 93  ? -18.258 47.135  49.472 1.00 13.44 ?  59   PHE B CA   1 
ATOM   6411  C C    . PHE B 1 93  ? -17.249 48.192  49.845 1.00 14.20 ?  59   PHE B C    1 
ATOM   6412  O O    . PHE B 1 93  ? -16.882 49.029  49.014 1.00 15.69 ?  59   PHE B O    1 
ATOM   6413  C CB   . PHE B 1 93  ? -17.527 46.001  48.748 1.00 13.14 ?  59   PHE B CB   1 
ATOM   6414  C CG   . PHE B 1 93  ? -18.355 44.758  48.578 1.00 13.18 ?  59   PHE B CG   1 
ATOM   6415  C CD1  . PHE B 1 93  ? -19.203 44.621  47.497 1.00 12.49 ?  59   PHE B CD1  1 
ATOM   6416  C CD2  . PHE B 1 93  ? -18.330 43.710  49.502 1.00 14.38 ?  59   PHE B CD2  1 
ATOM   6417  C CE1  . PHE B 1 93  ? -20.002 43.538  47.313 1.00 14.00 ?  59   PHE B CE1  1 
ATOM   6418  C CE2  . PHE B 1 93  ? -19.126 42.597  49.332 1.00 14.82 ?  59   PHE B CE2  1 
ATOM   6419  C CZ   . PHE B 1 93  ? -19.981 42.501  48.252 1.00 13.68 ?  59   PHE B CZ   1 
ATOM   6420  H H    . PHE B 1 93  ? -19.073 47.689  47.773 1.00 16.32 ?  59   PHE B H    1 
ATOM   6421  H HA   . PHE B 1 93  ? -18.666 46.792  50.283 1.00 16.13 ?  59   PHE B HA   1 
ATOM   6422  H HB2  . PHE B 1 93  ? -17.272 46.309  47.864 1.00 15.77 ?  59   PHE B HB2  1 
ATOM   6423  H HB3  . PHE B 1 93  ? -16.737 45.763  49.257 1.00 15.77 ?  59   PHE B HB3  1 
ATOM   6424  H HD1  . PHE B 1 93  ? -19.229 45.302  46.865 1.00 14.99 ?  59   PHE B HD1  1 
ATOM   6425  H HD2  . PHE B 1 93  ? -17.768 43.764  50.241 1.00 17.26 ?  59   PHE B HD2  1 
ATOM   6426  H HE1  . PHE B 1 93  ? -20.558 43.487  46.569 1.00 16.80 ?  59   PHE B HE1  1 
ATOM   6427  H HE2  . PHE B 1 93  ? -19.087 41.904  49.951 1.00 17.79 ?  59   PHE B HE2  1 
ATOM   6428  H HZ   . PHE B 1 93  ? -20.534 41.760  48.151 1.00 16.41 ?  59   PHE B HZ   1 
ATOM   6429  N N    . PRO B 1 94  ? -16.747 48.179  51.071 1.00 13.22 ?  60   PRO B N    1 
ATOM   6430  C CA   . PRO B 1 94  ? -15.764 49.191  51.445 1.00 13.52 ?  60   PRO B CA   1 
ATOM   6431  C C    . PRO B 1 94  ? -14.414 49.024  50.764 1.00 13.22 ?  60   PRO B C    1 
ATOM   6432  O O    . PRO B 1 94  ? -13.662 49.984  50.620 1.00 13.36 ?  60   PRO B O    1 
ATOM   6433  C CB   . PRO B 1 94  ? -15.646 49.022  52.959 1.00 15.24 ?  60   PRO B CB   1 
ATOM   6434  C CG   . PRO B 1 94  ? -16.159 47.667  53.236 1.00 16.05 ?  60   PRO B CG   1 
ATOM   6435  C CD   . PRO B 1 94  ? -17.218 47.414  52.220 1.00 13.29 ?  60   PRO B CD   1 
ATOM   6436  H HA   . PRO B 1 94  ? -16.114 50.072  51.240 1.00 16.23 ?  60   PRO B HA   1 
ATOM   6437  H HB2  . PRO B 1 94  ? -14.718 49.103  53.229 1.00 18.29 ?  60   PRO B HB2  1 
ATOM   6438  H HB3  . PRO B 1 94  ? -16.182 49.694  53.409 1.00 18.29 ?  60   PRO B HB3  1 
ATOM   6439  H HG2  . PRO B 1 94  ? -15.440 47.022  53.150 1.00 19.26 ?  60   PRO B HG2  1 
ATOM   6440  H HG3  . PRO B 1 94  ? -16.529 47.635  54.132 1.00 19.26 ?  60   PRO B HG3  1 
ATOM   6441  H HD2  . PRO B 1 94  ? -17.278 46.469  52.008 1.00 15.95 ?  60   PRO B HD2  1 
ATOM   6442  H HD3  . PRO B 1 94  ? -18.079 47.740  52.526 1.00 15.95 ?  60   PRO B HD3  1 
ATOM   6443  N N    . LEU B 1 95  ? -14.057 47.785  50.375 1.00 12.73 ?  61   LEU B N    1 
ATOM   6444  C CA   . LEU B 1 95  ? -12.735 47.489  49.839 1.00 12.24 ?  61   LEU B CA   1 
ATOM   6445  C C    . LEU B 1 95  ? -12.923 46.409  48.783 1.00 13.10 ?  61   LEU B C    1 
ATOM   6446  O O    . LEU B 1 95  ? -13.529 45.366  49.066 1.00 12.57 ?  61   LEU B O    1 
ATOM   6447  C CB   . LEU B 1 95  ? -11.796 47.006  50.946 1.00 13.13 ?  61   LEU B CB   1 
ATOM   6448  C CG   . LEU B 1 95  ? -10.360 46.706  50.572 1.00 12.78 ?  61   LEU B CG   1 
ATOM   6449  C CD1  . LEU B 1 95  ? -9.687  47.890  49.929 1.00 14.07 ?  61   LEU B CD1  1 
ATOM   6450  C CD2  . LEU B 1 95  ? -9.597  46.220  51.807 1.00 14.25 ?  61   LEU B CD2  1 
ATOM   6451  H H    . LEU B 1 95  ? -14.575 47.100  50.416 1.00 15.28 ?  61   LEU B H    1 
ATOM   6452  H HA   . LEU B 1 95  ? -12.335 48.274  49.433 1.00 14.68 ?  61   LEU B HA   1 
ATOM   6453  H HB2  . LEU B 1 95  ? -11.769 47.692  51.631 1.00 15.75 ?  61   LEU B HB2  1 
ATOM   6454  H HB3  . LEU B 1 95  ? -12.167 46.187  51.311 1.00 15.75 ?  61   LEU B HB3  1 
ATOM   6455  H HG   . LEU B 1 95  ? -10.346 45.999  49.908 1.00 15.33 ?  61   LEU B HG   1 
ATOM   6456  H HD11 . LEU B 1 95  ? -8.759  47.669  49.755 1.00 16.88 ?  61   LEU B HD11 1 
ATOM   6457  H HD12 . LEU B 1 95  ? -10.140 48.096  49.097 1.00 16.88 ?  61   LEU B HD12 1 
ATOM   6458  H HD13 . LEU B 1 95  ? -9.740  48.648  50.531 1.00 16.88 ?  61   LEU B HD13 1 
ATOM   6459  H HD21 . LEU B 1 95  ? -8.686  46.006  51.551 1.00 17.10 ?  61   LEU B HD21 1 
ATOM   6460  H HD22 . LEU B 1 95  ? -9.597  46.923  52.475 1.00 17.10 ?  61   LEU B HD22 1 
ATOM   6461  H HD23 . LEU B 1 95  ? -10.036 45.430  52.159 1.00 17.10 ?  61   LEU B HD23 1 
ATOM   6462  N N    . ILE B 1 96  ? -12.435 46.689  47.575 1.00 11.69 ?  62   ILE B N    1 
ATOM   6463  C CA   . ILE B 1 96  ? -12.586 45.822  46.410 1.00 12.26 ?  62   ILE B CA   1 
ATOM   6464  C C    . ILE B 1 96  ? -11.217 45.645  45.764 1.00 12.50 ?  62   ILE B C    1 
ATOM   6465  O O    . ILE B 1 96  ? -10.560 46.634  45.425 1.00 13.17 ?  62   ILE B O    1 
ATOM   6466  C CB   . ILE B 1 96  ? -13.535 46.464  45.376 1.00 13.07 ?  62   ILE B CB   1 
ATOM   6467  C CG1  . ILE B 1 96  ? -14.866 46.833  45.999 1.00 14.20 ?  62   ILE B CG1  1 
ATOM   6468  C CG2  . ILE B 1 96  ? -13.744 45.505  44.194 1.00 13.36 ?  62   ILE B CG2  1 
ATOM   6469  C CD1  . ILE B 1 96  ? -15.139 48.301  45.930 1.00 18.13 ?  62   ILE B CD1  1 
ATOM   6470  H H    . ILE B 1 96  ? -11.995 47.407  47.400 1.00 14.03 ?  62   ILE B H    1 
ATOM   6471  H HA   . ILE B 1 96  ? -12.924 44.957  46.692 1.00 14.72 ?  62   ILE B HA   1 
ATOM   6472  H HB   . ILE B 1 96  ? -13.122 47.283  45.058 1.00 15.68 ?  62   ILE B HB   1 
ATOM   6473  H HG12 . ILE B 1 96  ? -15.576 46.371  45.527 1.00 17.05 ?  62   ILE B HG12 1 
ATOM   6474  H HG13 . ILE B 1 96  ? -14.863 46.570  46.933 1.00 17.05 ?  62   ILE B HG13 1 
ATOM   6475  H HG21 . ILE B 1 96  ? -14.418 45.876  43.603 1.00 16.03 ?  62   ILE B HG21 1 
ATOM   6476  H HG22 . ILE B 1 96  ? -12.906 45.404  43.717 1.00 16.03 ?  62   ILE B HG22 1 
ATOM   6477  H HG23 . ILE B 1 96  ? -14.038 44.646  44.533 1.00 16.03 ?  62   ILE B HG23 1 
ATOM   6478  H HD11 . ILE B 1 96  ? -15.947 48.496  46.431 1.00 21.76 ?  62   ILE B HD11 1 
ATOM   6479  H HD12 . ILE B 1 96  ? -14.389 48.780  46.314 1.00 21.76 ?  62   ILE B HD12 1 
ATOM   6480  H HD13 . ILE B 1 96  ? -15.255 48.557  45.002 1.00 21.76 ?  62   ILE B HD13 1 
ATOM   6481  N N    . THR B 1 97  ? -10.815 44.388  45.517 1.00 11.40 ?  63   THR B N    1 
ATOM   6482  C CA   . THR B 1 97  ? -9.665  44.106  44.658 1.00 11.43 ?  63   THR B CA   1 
ATOM   6483  C C    . THR B 1 97  ? -10.179 43.668  43.293 1.00 11.13 ?  63   THR B C    1 
ATOM   6484  O O    . THR B 1 97  ? -10.982 42.739  43.187 1.00 11.44 ?  63   THR B O    1 
ATOM   6485  C CB   . THR B 1 97  ? -8.777  43.004  45.264 1.00 12.31 ?  63   THR B CB   1 
ATOM   6486  O OG1  . THR B 1 97  ? -8.204  43.525  46.456 1.00 12.16 ?  63   THR B OG1  1 
ATOM   6487  C CG2  . THR B 1 97  ? -7.644  42.598  44.308 1.00 12.15 ?  63   THR B CG2  1 
ATOM   6488  H H    . THR B 1 97  ? -11.196 43.687  45.838 1.00 13.68 ?  63   THR B H    1 
ATOM   6489  H HA   . THR B 1 97  ? -9.124  44.905  44.559 1.00 13.71 ?  63   THR B HA   1 
ATOM   6490  H HB   . THR B 1 97  ? -9.307  42.211  45.439 1.00 14.77 ?  63   THR B HB   1 
ATOM   6491  H HG1  . THR B 1 97  ? -8.093  42.907  47.015 1.00 14.60 ?  63   THR B HG1  1 
ATOM   6492  H HG21 . THR B 1 97  ? -6.988  42.061  44.780 1.00 14.58 ?  63   THR B HG21 1 
ATOM   6493  H HG22 . THR B 1 97  ? -8.003  42.080  43.570 1.00 14.58 ?  63   THR B HG22 1 
ATOM   6494  H HG23 . THR B 1 97  ? -7.208  43.389  43.955 1.00 14.58 ?  63   THR B HG23 1 
ATOM   6495  N N    . LEU B 1 98  ? -9.690  44.339  42.263 1.00 10.84 ?  64   LEU B N    1 
ATOM   6496  C CA   . LEU B 1 98  ? -9.920  43.946  40.887 1.00 10.99 ?  64   LEU B CA   1 
ATOM   6497  C C    . LEU B 1 98  ? -8.779  43.022  40.474 1.00 10.97 ?  64   LEU B C    1 
ATOM   6498  O O    . LEU B 1 98  ? -7.626  43.428  40.377 1.00 11.36 ?  64   LEU B O    1 
ATOM   6499  C CB   . LEU B 1 98  ? -10.023 45.172  39.979 1.00 11.11 ?  64   LEU B CB   1 
ATOM   6500  C CG   . LEU B 1 98  ? -11.145 46.149  40.352 1.00 11.58 ?  64   LEU B CG   1 
ATOM   6501  C CD1  . LEU B 1 98  ? -11.129 47.374  39.420 1.00 14.61 ?  64   LEU B CD1  1 
ATOM   6502  C CD2  . LEU B 1 98  ? -12.477 45.482  40.302 1.00 12.19 ?  64   LEU B CD2  1 
ATOM   6503  H H    . LEU B 1 98  ? -9.207  45.047  42.339 1.00 13.01 ?  64   LEU B H    1 
ATOM   6504  H HA   . LEU B 1 98  ? -10.757 43.461  40.812 1.00 13.19 ?  64   LEU B HA   1 
ATOM   6505  H HB2  . LEU B 1 98  ? -9.185  45.658  40.021 1.00 13.34 ?  64   LEU B HB2  1 
ATOM   6506  H HB3  . LEU B 1 98  ? -10.187 44.870  39.072 1.00 13.34 ?  64   LEU B HB3  1 
ATOM   6507  H HG   . LEU B 1 98  ? -10.996 46.453  41.262 1.00 13.90 ?  64   LEU B HG   1 
ATOM   6508  H HD11 . LEU B 1 98  ? -11.865 47.960  39.657 1.00 17.54 ?  64   LEU B HD11 1 
ATOM   6509  H HD12 . LEU B 1 98  ? -10.286 47.841  39.527 1.00 17.54 ?  64   LEU B HD12 1 
ATOM   6510  H HD13 . LEU B 1 98  ? -11.227 47.073  38.503 1.00 17.54 ?  64   LEU B HD13 1 
ATOM   6511  H HD21 . LEU B 1 98  ? -13.170 46.154  40.398 1.00 14.63 ?  64   LEU B HD21 1 
ATOM   6512  H HD22 . LEU B 1 98  ? -12.571 45.029  39.449 1.00 14.63 ?  64   LEU B HD22 1 
ATOM   6513  H HD23 . LEU B 1 98  ? -12.536 44.840  41.026 1.00 14.63 ?  64   LEU B HD23 1 
ATOM   6514  N N    . GLU B 1 99  ? -9.157  41.770  40.221 1.00 10.56 ?  65   GLU B N    1 
ATOM   6515  C CA   . GLU B 1 99  ? -8.243  40.720  39.785 1.00 10.36 ?  65   GLU B CA   1 
ATOM   6516  C C    . GLU B 1 99  ? -7.701  40.951  38.372 1.00 10.58 ?  65   GLU B C    1 
ATOM   6517  O O    . GLU B 1 99  ? -8.122  41.860  37.627 1.00 11.28 ?  65   GLU B O    1 
ATOM   6518  C CB   . GLU B 1 99  ? -8.949  39.356  39.805 1.00 12.83 ?  65   GLU B CB   1 
ATOM   6519  C CG   . GLU B 1 99  ? -8.689  38.567  41.080 1.00 12.63 ?  65   GLU B CG   1 
ATOM   6520  C CD   . GLU B 1 99  ? -7.311  37.912  41.122 1.00 11.88 ?  65   GLU B CD   1 
ATOM   6521  O OE1  . GLU B 1 99  ? -6.581  37.922  40.101 1.00 12.07 ?  65   GLU B OE1  1 
ATOM   6522  O OE2  . GLU B 1 99  ? -7.008  37.382  42.201 1.00 12.49 ?  65   GLU B OE2  1 
ATOM   6523  H H    . GLU B 1 99  ? -9.967  41.493  40.298 1.00 12.67 ?  65   GLU B H    1 
ATOM   6524  H HA   . GLU B 1 99  ? -7.492  40.727  40.399 1.00 12.43 ?  65   GLU B HA   1 
ATOM   6525  H HB2  . GLU B 1 99  ? -9.906  39.496  39.730 1.00 15.40 ?  65   GLU B HB2  1 
ATOM   6526  H HB3  . GLU B 1 99  ? -8.632  38.827  39.056 1.00 15.40 ?  65   GLU B HB3  1 
ATOM   6527  H HG2  . GLU B 1 99  ? -8.755  39.167  41.839 1.00 15.16 ?  65   GLU B HG2  1 
ATOM   6528  H HG3  . GLU B 1 99  ? -9.353  37.864  41.154 1.00 15.16 ?  65   GLU B HG3  1 
ATOM   6529  N N    . LYS B 1 100 ? -6.695  40.160  38.029 1.00 11.61 ?  66   LYS B N    1 
ATOM   6530  C CA   . LYS B 1 100 ? -6.282  40.002  36.653 1.00 11.56 ?  66   LYS B CA   1 
ATOM   6531  C C    . LYS B 1 100 ? -7.474  39.566  35.781 1.00 11.09 ?  66   LYS B C    1 
ATOM   6532  O O    . LYS B 1 100 ? -8.524  39.161  36.250 1.00 12.53 ?  66   LYS B O    1 
ATOM   6533  C CB   . LYS B 1 100 ? -5.123  39.003  36.588 1.00 10.94 ?  66   LYS B CB   1 
ATOM   6534  C CG   . LYS B 1 100 ? -5.499  37.620  37.075 1.00 14.76 ?  66   LYS B CG   1 
ATOM   6535  C CD   . LYS B 1 100 ? -4.285  36.661  37.220 1.00 11.70 ?  66   LYS B CD   1 
ATOM   6536  C CE   . LYS B 1 100 ? -4.579  35.476  38.094 1.00 14.14 ?  66   LYS B CE   1 
ATOM   6537  N NZ   . LYS B 1 100 ? -4.858  35.775  39.516 1.00 13.68 ?  66   LYS B NZ   1 
ATOM   6538  H H    . LYS B 1 100 ? -6.231  39.697  38.585 1.00 13.93 ?  66   LYS B H    1 
ATOM   6539  H HA   . LYS B 1 100 ? -5.968  40.844  36.288 1.00 13.87 ?  66   LYS B HA   1 
ATOM   6540  H HB2  . LYS B 1 100 ? -4.827  38.925  35.668 1.00 13.13 ?  66   LYS B HB2  1 
ATOM   6541  H HB3  . LYS B 1 100 ? -4.397  39.328  37.144 1.00 13.13 ?  66   LYS B HB3  1 
ATOM   6542  H HG2  . LYS B 1 100 ? -5.920  37.698  37.945 1.00 17.72 ?  66   LYS B HG2  1 
ATOM   6543  H HG3  . LYS B 1 100 ? -6.116  37.222  36.442 1.00 17.72 ?  66   LYS B HG3  1 
ATOM   6544  H HD2  . LYS B 1 100 ? -4.036  36.332  36.343 1.00 14.04 ?  66   LYS B HD2  1 
ATOM   6545  H HD3  . LYS B 1 100 ? -3.544  37.147  37.615 1.00 14.04 ?  66   LYS B HD3  1 
ATOM   6546  H HE2  . LYS B 1 100 ? -5.360  35.023  37.738 1.00 16.97 ?  66   LYS B HE2  1 
ATOM   6547  H HE3  . LYS B 1 100 ? -3.812  34.883  38.070 1.00 16.97 ?  66   LYS B HE3  1 
ATOM   6548  H HZ1  . LYS B 1 100 ? -5.072  35.027  39.948 1.00 16.42 ?  66   LYS B HZ1  1 
ATOM   6549  H HZ2  . LYS B 1 100 ? -4.138  36.134  39.899 1.00 16.42 ?  66   LYS B HZ2  1 
ATOM   6550  H HZ3  . LYS B 1 100 ? -5.535  36.349  39.580 1.00 16.42 ?  66   LYS B HZ3  1 
ATOM   6551  N N    . SER B 1 101 ? -7.254  39.687  34.462 1.00 11.73 ?  67   SER B N    1 
ATOM   6552  C CA   . SER B 1 101 ? -8.309  39.444  33.473 1.00 11.51 ?  67   SER B CA   1 
ATOM   6553  C C    . SER B 1 101 ? -9.575  40.230  33.801 1.00 11.76 ?  67   SER B C    1 
ATOM   6554  O O    . SER B 1 101 ? -10.662 39.717  34.033 1.00 11.40 ?  67   SER B O    1 
ATOM   6555  C CB   . SER B 1 101 ? -8.590  37.958  33.277 1.00 12.90 ?  67   SER B CB   1 
ATOM   6556  O OG   . SER B 1 101 ? -7.456  37.373  32.658 1.00 14.43 ?  67   SER B OG   1 
ATOM   6557  H H    . SER B 1 101 ? -6.498  39.909  34.118 1.00 14.08 ?  67   SER B H    1 
ATOM   6558  H HA   . SER B 1 101 ? -7.984  39.775  32.621 1.00 13.81 ?  67   SER B HA   1 
ATOM   6559  H HB2  . SER B 1 101 ? -8.744  37.538  34.138 1.00 15.48 ?  67   SER B HB2  1 
ATOM   6560  H HB3  . SER B 1 101 ? -9.367  37.844  32.708 1.00 15.48 ?  67   SER B HB3  1 
ATOM   6561  H HG   . SER B 1 101 ? -7.551  36.540  32.613 1.00 17.32 ?  67   SER B HG   1 
ATOM   6562  N N    . GLN B 1 102 ? -9.374  41.557  33.777 1.00 11.81 ?  68   GLN B N    1 
ATOM   6563  C CA   . GLN B 1 102 ? -10.420 42.475  34.226 1.00 12.40 ?  68   GLN B CA   1 
ATOM   6564  C C    . GLN B 1 102 ? -11.136 43.084  33.023 1.00 11.58 ?  68   GLN B C    1 
ATOM   6565  O O    . GLN B 1 102 ? -10.699 44.111  32.484 1.00 12.52 ?  68   GLN B O    1 
ATOM   6566  C CB   . GLN B 1 102 ? -9.822  43.550  35.111 1.00 11.35 ?  68   GLN B CB   1 
ATOM   6567  C CG   . GLN B 1 102 ? -10.878 44.283  35.916 1.00 11.80 ?  68   GLN B CG   1 
ATOM   6568  C CD   . GLN B 1 102 ? -11.657 43.433  36.927 1.00 12.47 ?  68   GLN B CD   1 
ATOM   6569  O OE1  . GLN B 1 102 ? -12.890 43.513  37.038 1.00 13.45 ?  68   GLN B OE1  1 
ATOM   6570  N NE2  . GLN B 1 102 ? -10.937 42.575  37.669 1.00 11.97 ?  68   GLN B NE2  1 
ATOM   6571  H H    . GLN B 1 102 ? -8.651  41.937  33.509 1.00 14.17 ?  68   GLN B H    1 
ATOM   6572  H HA   . GLN B 1 102 ? -11.078 41.963  34.721 1.00 14.88 ?  68   GLN B HA   1 
ATOM   6573  H HB2  . GLN B 1 102 ? -9.199  43.141  35.731 1.00 13.62 ?  68   GLN B HB2  1 
ATOM   6574  H HB3  . GLN B 1 102 ? -9.361  44.199  34.556 1.00 13.62 ?  68   GLN B HB3  1 
ATOM   6575  H HG2  . GLN B 1 102 ? -10.443 44.993  36.414 1.00 14.16 ?  68   GLN B HG2  1 
ATOM   6576  H HG3  . GLN B 1 102 ? -11.525 44.659  35.299 1.00 14.16 ?  68   GLN B HG3  1 
ATOM   6577  H HE21 . GLN B 1 102 ? -10.085 42.525  37.562 1.00 14.37 ?  68   GLN B HE21 1 
ATOM   6578  H HE22 . GLN B 1 102 ? -11.328 42.076  38.250 1.00 14.37 ?  68   GLN B HE22 1 
ATOM   6579  N N    . ALA B 1 103 ? -12.239 42.441  32.645 1.00 12.17 ?  69   ALA B N    1 
ATOM   6580  C CA   . ALA B 1 103 ? -13.111 42.898  31.556 1.00 11.89 ?  69   ALA B CA   1 
ATOM   6581  C C    . ALA B 1 103 ? -12.378 43.067  30.243 1.00 15.29 ?  69   ALA B C    1 
ATOM   6582  O O    . ALA B 1 103 ? -12.722 43.936  29.425 1.00 14.45 ?  69   ALA B O    1 
ATOM   6583  C CB   . ALA B 1 103 ? -13.842 44.170  31.970 1.00 14.24 ?  69   ALA B CB   1 
ATOM   6584  H H    . ALA B 1 103 ? -12.515 41.715  33.013 1.00 14.61 ?  69   ALA B H    1 
ATOM   6585  H HA   . ALA B 1 103 ? -13.774 42.211  31.383 1.00 14.27 ?  69   ALA B HA   1 
ATOM   6586  H HB1  . ALA B 1 103 ? -14.455 44.427  31.263 1.00 17.09 ?  69   ALA B HB1  1 
ATOM   6587  H HB2  . ALA B 1 103 ? -14.334 44.000  32.788 1.00 17.09 ?  69   ALA B HB2  1 
ATOM   6588  H HB3  . ALA B 1 103 ? -13.192 44.875  32.115 1.00 17.09 ?  69   ALA B HB3  1 
ATOM   6589  N N    . GLN B 1 104 ? -11.370 42.217  30.005 1.00 13.59 ?  70   GLN B N    1 
ATOM   6590  C CA   . GLN B 1 104 ? -10.518 42.398  28.851 1.00 13.71 ?  70   GLN B CA   1 
ATOM   6591  C C    . GLN B 1 104 ? -11.230 42.142  27.528 1.00 14.74 ?  70   GLN B C    1 
ATOM   6592  O O    . GLN B 1 104 ? -10.749 42.635  26.503 1.00 17.27 ?  70   GLN B O    1 
ATOM   6593  C CB   . GLN B 1 104 ? -9.277  41.500  28.961 1.00 14.56 ?  70   GLN B CB   1 
ATOM   6594  C CG   . GLN B 1 104 ? -9.500  40.037  28.679 1.00 14.63 ?  70   GLN B CG   1 
ATOM   6595  C CD   . GLN B 1 104 ? -10.236 39.293  29.759 1.00 13.51 ?  70   GLN B CD   1 
ATOM   6596  O OE1  . GLN B 1 104 ? -10.324 39.737  30.898 1.00 14.88 ?  70   GLN B OE1  1 
ATOM   6597  N NE2  . GLN B 1 104 ? -10.754 38.111  29.431 1.00 16.08 ?  70   GLN B NE2  1 
ATOM   6598  H H    . GLN B 1 104 ? -11.171 41.540  30.496 1.00 16.31 ?  70   GLN B H    1 
ATOM   6599  H HA   . GLN B 1 104 ? -10.223 43.322  28.841 1.00 16.45 ?  70   GLN B HA   1 
ATOM   6600  H HB2  . GLN B 1 104 ? -8.615  41.818  28.327 1.00 17.48 ?  70   GLN B HB2  1 
ATOM   6601  H HB3  . GLN B 1 104 ? -8.931  41.570  29.865 1.00 17.48 ?  70   GLN B HB3  1 
ATOM   6602  H HG2  . GLN B 1 104 ? -10.018 39.955  27.863 1.00 17.56 ?  70   GLN B HG2  1 
ATOM   6603  H HG3  . GLN B 1 104 ? -8.636  39.609  28.567 1.00 17.56 ?  70   GLN B HG3  1 
ATOM   6604  H HE21 . GLN B 1 104 ? -10.659 37.807  28.632 1.00 19.30 ?  70   GLN B HE21 1 
ATOM   6605  H HE22 . GLN B 1 104 ? -11.183 37.651  30.017 1.00 19.30 ?  70   GLN B HE22 1 
ATOM   6606  N N    . ASN B 1 105 ? -12.321 41.396  27.520 1.00 14.21 ?  71   ASN B N    1 
ATOM   6607  C CA   . ASN B 1 105 ? -13.044 41.124  26.291 1.00 16.95 ?  71   ASN B CA   1 
ATOM   6608  C C    . ASN B 1 105 ? -14.059 42.203  25.961 1.00 18.31 ?  71   ASN B C    1 
ATOM   6609  O O    . ASN B 1 105 ? -14.749 42.094  24.938 1.00 22.44 ?  71   ASN B O    1 
ATOM   6610  C CB   . ASN B 1 105 ? -13.698 39.740  26.327 1.00 17.07 ?  71   ASN B CB   1 
ATOM   6611  C CG   . ASN B 1 105 ? -12.661 38.603  26.369 1.00 17.23 ?  71   ASN B CG   1 
ATOM   6612  O OD1  . ASN B 1 105 ? -11.496 38.811  26.106 1.00 17.54 ?  71   ASN B OD1  1 
ATOM   6613  N ND2  . ASN B 1 105 ? -13.106 37.420  26.730 1.00 19.94 ?  71   ASN B ND2  1 
ATOM   6614  H H    . ASN B 1 105 ? -12.665 41.033  28.220 1.00 17.06 ?  71   ASN B H    1 
ATOM   6615  H HA   . ASN B 1 105 ? -12.409 41.095  25.559 1.00 20.34 ?  71   ASN B HA   1 
ATOM   6616  H HB2  . ASN B 1 105 ? -14.252 39.672  27.120 1.00 20.48 ?  71   ASN B HB2  1 
ATOM   6617  H HB3  . ASN B 1 105 ? -14.240 39.625  25.532 1.00 20.48 ?  71   ASN B HB3  1 
ATOM   6618  H HD21 . ASN B 1 105 ? -12.566 36.751  26.769 1.00 23.93 ?  71   ASN B HD21 1 
ATOM   6619  H HD22 . ASN B 1 105 ? -13.936 37.315  26.927 1.00 23.93 ?  71   ASN B HD22 1 
ATOM   6620  N N    . THR B 1 106 ? -14.182 43.230  26.790 1.00 15.20 ?  72   THR B N    1 
ATOM   6621  C CA   . THR B 1 106 ? -14.888 44.445  26.407 1.00 14.72 ?  72   THR B CA   1 
ATOM   6622  C C    . THR B 1 106 ? -13.935 45.589  26.095 1.00 16.21 ?  72   THR B C    1 
ATOM   6623  O O    . THR B 1 106 ? -14.126 46.329  25.105 1.00 17.17 ?  72   THR B O    1 
ATOM   6624  C CB   . THR B 1 106 ? -15.813 44.872  27.544 1.00 14.31 ?  72   THR B CB   1 
ATOM   6625  O OG1  . THR B 1 106 ? -16.766 43.888  27.826 1.00 15.43 ?  72   THR B OG1  1 
ATOM   6626  C CG2  . THR B 1 106 ? -16.492 46.223  27.173 1.00 16.23 ?  72   THR B CG2  1 
ATOM   6627  H H    . THR B 1 106 ? -13.862 43.248  27.588 1.00 18.24 ?  72   THR B H    1 
ATOM   6628  H HA   . THR B 1 106 ? -15.427 44.272  25.619 1.00 17.67 ?  72   THR B HA   1 
ATOM   6629  H HB   . THR B 1 106 ? -15.298 44.997  28.357 1.00 17.17 ?  72   THR B HB   1 
ATOM   6630  H HG1  . THR B 1 106 ? -17.147 43.646  27.118 1.00 18.52 ?  72   THR B HG1  1 
ATOM   6631  H HG21 . THR B 1 106 ? -17.302 46.341  27.694 1.00 19.48 ?  72   THR B HG21 1 
ATOM   6632  H HG22 . THR B 1 106 ? -15.889 46.959  27.358 1.00 19.48 ?  72   THR B HG22 1 
ATOM   6633  H HG23 . THR B 1 106 ? -16.720 46.231  26.231 1.00 19.48 ?  72   THR B HG23 1 
ATOM   6634  N N    . TYR B 1 107 ? -12.885 45.764  26.895 1.00 14.27 ?  73   TYR B N    1 
ATOM   6635  C CA   . TYR B 1 107 ? -12.011 46.919  26.850 1.00 16.80 ?  73   TYR B CA   1 
ATOM   6636  C C    . TYR B 1 107 ? -10.668 46.635  26.188 1.00 15.65 ?  73   TYR B C    1 
ATOM   6637  O O    . TYR B 1 107 ? -9.865  47.552  26.034 1.00 18.34 ?  73   TYR B O    1 
ATOM   6638  C CB   . TYR B 1 107 ? -11.821 47.489  28.269 1.00 14.77 ?  73   TYR B CB   1 
ATOM   6639  C CG   . TYR B 1 107 ? -13.117 47.951  28.855 1.00 14.93 ?  73   TYR B CG   1 
ATOM   6640  C CD1  . TYR B 1 107 ? -13.712 49.151  28.416 1.00 16.40 ?  73   TYR B CD1  1 
ATOM   6641  C CD2  . TYR B 1 107 ? -13.787 47.202  29.792 1.00 14.03 ?  73   TYR B CD2  1 
ATOM   6642  C CE1  . TYR B 1 107 ? -14.912 49.562  28.929 1.00 18.44 ?  73   TYR B CE1  1 
ATOM   6643  C CE2  . TYR B 1 107 ? -15.008 47.600  30.304 1.00 15.41 ?  73   TYR B CE2  1 
ATOM   6644  C CZ   . TYR B 1 107 ? -15.565 48.793  29.866 1.00 16.05 ?  73   TYR B CZ   1 
ATOM   6645  O OH   . TYR B 1 107 ? -16.796 49.166  30.376 1.00 18.12 ?  73   TYR B OH   1 
ATOM   6646  H H    . TYR B 1 107 ? -12.652 45.197  27.498 1.00 17.13 ?  73   TYR B H    1 
ATOM   6647  H HA   . TYR B 1 107 ? -12.435 47.611  26.320 1.00 20.15 ?  73   TYR B HA   1 
ATOM   6648  H HB2  . TYR B 1 107 ? -11.453 46.801  28.845 1.00 17.72 ?  73   TYR B HB2  1 
ATOM   6649  H HB3  . TYR B 1 107 ? -11.217 48.247  28.231 1.00 17.72 ?  73   TYR B HB3  1 
ATOM   6650  H HD1  . TYR B 1 107 ? -13.285 49.668  27.772 1.00 19.67 ?  73   TYR B HD1  1 
ATOM   6651  H HD2  . TYR B 1 107 ? -13.409 46.406  30.090 1.00 16.83 ?  73   TYR B HD2  1 
ATOM   6652  H HE1  . TYR B 1 107 ? -15.288 50.363  28.643 1.00 22.13 ?  73   TYR B HE1  1 
ATOM   6653  H HE2  . TYR B 1 107 ? -15.450 47.075  30.932 1.00 18.49 ?  73   TYR B HE2  1 
ATOM   6654  H HH   . TYR B 1 107 ? -17.030 49.904  30.050 1.00 21.75 ?  73   TYR B HH   1 
ATOM   6655  N N    . GLY B 1 108 ? -10.424 45.385  25.799 1.00 15.04 ?  74   GLY B N    1 
ATOM   6656  C CA   . GLY B 1 108 ? -9.238  45.002  25.057 1.00 17.09 ?  74   GLY B CA   1 
ATOM   6657  C C    . GLY B 1 108 ? -8.048  44.601  25.899 1.00 18.50 ?  74   GLY B C    1 
ATOM   6658  O O    . GLY B 1 108 ? -7.104  43.988  25.368 1.00 20.01 ?  74   GLY B O    1 
ATOM   6659  H H    . GLY B 1 108 ? -10.951 44.725  25.959 1.00 18.05 ?  74   GLY B H    1 
ATOM   6660  H HA2  . GLY B 1 108 ? -9.461  44.250  24.486 1.00 20.51 ?  74   GLY B HA2  1 
ATOM   6661  H HA3  . GLY B 1 108 ? -8.966  45.750  24.502 1.00 20.51 ?  74   GLY B HA3  1 
ATOM   6662  N N    . SER B 1 109 ? -8.054  44.917  27.197 1.00 15.61 ?  75   SER B N    1 
ATOM   6663  C CA   . SER B 1 109 ? -6.948  44.616  28.076 1.00 14.18 ?  75   SER B CA   1 
ATOM   6664  C C    . SER B 1 109 ? -7.425  44.772  29.513 1.00 15.13 ?  75   SER B C    1 
ATOM   6665  O O    . SER B 1 109 ? -8.416  45.456  29.797 1.00 14.84 ?  75   SER B O    1 
ATOM   6666  C CB   . SER B 1 109 ? -5.786  45.560  27.858 1.00 16.05 ?  75   SER B CB   1 
ATOM   6667  O OG   . SER B 1 109 ? -6.115  46.916  28.169 1.00 16.03 ?  75   SER B OG   1 
ATOM   6668  H H    . SER B 1 109 ? -8.706  45.316  27.591 1.00 18.73 ?  75   SER B H    1 
ATOM   6669  H HA   . SER B 1 109 ? -6.663  43.703  27.916 1.00 17.02 ?  75   SER B HA   1 
ATOM   6670  H HB2  . SER B 1 109 ? -5.051  45.281  28.427 1.00 19.26 ?  75   SER B HB2  1 
ATOM   6671  H HB3  . SER B 1 109 ? -5.520  45.512  26.926 1.00 19.26 ?  75   SER B HB3  1 
ATOM   6672  H HG   . SER B 1 109 ? -6.782  47.160  27.721 1.00 19.24 ?  75   SER B HG   1 
ATOM   6673  N N    . THR B 1 110 ? -6.696  44.113  30.420 1.00 14.14 ?  76   THR B N    1 
ATOM   6674  C CA   . THR B 1 110 ? -6.942  44.299  31.845 1.00 12.07 ?  76   THR B CA   1 
ATOM   6675  C C    . THR B 1 110 ? -6.665  45.734  32.257 1.00 14.08 ?  76   THR B C    1 
ATOM   6676  O O    . THR B 1 110 ? -7.380  46.277  33.122 1.00 13.25 ?  76   THR B O    1 
ATOM   6677  C CB   . THR B 1 110 ? -6.099  43.309  32.611 1.00 12.15 ?  76   THR B CB   1 
ATOM   6678  O OG1  . THR B 1 110 ? -6.709  42.036  32.411 1.00 13.23 ?  76   THR B OG1  1 
ATOM   6679  C CG2  . THR B 1 110 ? -6.032  43.635  34.110 1.00 13.01 ?  76   THR B CG2  1 
ATOM   6680  H H    . THR B 1 110 ? -6.062  43.561  30.235 1.00 16.97 ?  76   THR B H    1 
ATOM   6681  H HA   . THR B 1 110 ? -7.872  44.124  32.059 1.00 14.48 ?  76   THR B HA   1 
ATOM   6682  H HB   . THR B 1 110 ? -5.179  43.323  32.302 1.00 14.59 ?  76   THR B HB   1 
ATOM   6683  H HG1  . THR B 1 110 ? -7.205  42.058  31.734 1.00 15.88 ?  76   THR B HG1  1 
ATOM   6684  H HG21 . THR B 1 110 ? -5.504  42.965  34.573 1.00 15.62 ?  76   THR B HG21 1 
ATOM   6685  H HG22 . THR B 1 110 ? -5.623  44.505  34.243 1.00 15.62 ?  76   THR B HG22 1 
ATOM   6686  H HG23 . THR B 1 110 ? -6.926  43.647  34.487 1.00 15.62 ?  76   THR B HG23 1 
ATOM   6687  N N    . GLU B 1 111 ? -5.649  46.372  31.674 1.00 13.90 ?  77   GLU B N    1 
ATOM   6688  C CA   . GLU B 1 111 ? -5.329  47.740  32.083 1.00 13.83 ?  77   GLU B CA   1 
ATOM   6689  C C    . GLU B 1 111 ? -6.515  48.661  31.821 1.00 13.43 ?  77   GLU B C    1 
ATOM   6690  O O    . GLU B 1 111 ? -6.972  49.379  32.712 1.00 13.92 ?  77   GLU B O    1 
ATOM   6691  C CB   . GLU B 1 111 ? -4.079  48.234  31.363 1.00 14.10 ?  77   GLU B CB   1 
ATOM   6692  C CG   . GLU B 1 111 ? -2.805  47.472  31.721 1.00 15.45 ?  77   GLU B CG   1 
ATOM   6693  C CD   . GLU B 1 111 ? -2.491  46.339  30.757 1.00 13.26 ?  77   GLU B CD   1 
ATOM   6694  O OE1  . GLU B 1 111 ? -3.418  45.783  30.169 1.00 13.84 ?  77   GLU B OE1  1 
ATOM   6695  O OE2  . GLU B 1 111 ? -1.270  46.021  30.650 1.00 14.97 ?  77   GLU B OE2  1 
ATOM   6696  H H    . GLU B 1 111 ? -5.145  46.047  31.058 1.00 16.68 ?  77   GLU B H    1 
ATOM   6697  H HA   . GLU B 1 111 ? -5.135  47.753  33.034 1.00 16.60 ?  77   GLU B HA   1 
ATOM   6698  H HB2  . GLU B 1 111 ? -4.216  48.143  30.407 1.00 16.91 ?  77   GLU B HB2  1 
ATOM   6699  H HB3  . GLU B 1 111 ? -3.938  49.166  31.591 1.00 16.91 ?  77   GLU B HB3  1 
ATOM   6700  H HG2  . GLU B 1 111 ? -2.056  48.089  31.708 1.00 18.54 ?  77   GLU B HG2  1 
ATOM   6701  H HG3  . GLU B 1 111 ? -2.905  47.091  32.607 1.00 18.54 ?  77   GLU B HG3  1 
ATOM   6702  N N    . GLU B 1 112 ? -7.077  48.594  30.630 1.00 14.04 ?  78   GLU B N    1 
ATOM   6703  C CA   . GLU B 1 112 ? -8.204  49.474  30.311 1.00 12.96 ?  78   GLU B CA   1 
ATOM   6704  C C    . GLU B 1 112 ? -9.494  49.008  30.945 1.00 14.81 ?  78   GLU B C    1 
ATOM   6705  O O    . GLU B 1 112 ? -10.336 49.847  31.309 1.00 14.23 ?  78   GLU B O    1 
ATOM   6706  C CB   . GLU B 1 112 ? -8.338  49.643  28.812 1.00 17.16 ?  78   GLU B CB   1 
ATOM   6707  C CG   . GLU B 1 112 ? -7.211  50.471  28.180 1.00 18.61 ?  78   GLU B CG   1 
ATOM   6708  C CD   . GLU B 1 112 ? -7.198  51.958  28.568 1.00 23.48 ?  78   GLU B CD   1 
ATOM   6709  O OE1  . GLU B 1 112 ? -8.284  52.556  28.788 1.00 21.06 ?  78   GLU B OE1  1 
ATOM   6710  O OE2  . GLU B 1 112 ? -6.078  52.507  28.672 1.00 26.98 ?  78   GLU B OE2  1 
ATOM   6711  H H    . GLU B 1 112 ? -6.837  48.064  29.997 1.00 16.84 ?  78   GLU B H    1 
ATOM   6712  H HA   . GLU B 1 112 ? -8.024  50.357  30.670 1.00 15.55 ?  78   GLU B HA   1 
ATOM   6713  H HB2  . GLU B 1 112 ? -8.329  48.766  28.397 1.00 20.60 ?  78   GLU B HB2  1 
ATOM   6714  H HB3  . GLU B 1 112 ? -9.177  50.092  28.623 1.00 20.60 ?  78   GLU B HB3  1 
ATOM   6715  H HG2  . GLU B 1 112 ? -6.361  50.093  28.454 1.00 22.33 ?  78   GLU B HG2  1 
ATOM   6716  H HG3  . GLU B 1 112 ? -7.299  50.425  27.215 1.00 22.33 ?  78   GLU B HG3  1 
ATOM   6717  N N    . GLY B 1 113 ? -9.684  47.699  31.132 1.00 13.52 ?  79   GLY B N    1 
ATOM   6718  C CA   . GLY B 1 113 ? -10.874 47.248  31.822 1.00 13.45 ?  79   GLY B CA   1 
ATOM   6719  C C    . GLY B 1 113 ? -10.876 47.605  33.292 1.00 13.00 ?  79   GLY B C    1 
ATOM   6720  O O    . GLY B 1 113 ? -11.934 47.905  33.867 1.00 13.27 ?  79   GLY B O    1 
ATOM   6721  H H    . GLY B 1 113 ? -9.150  47.076  30.875 1.00 16.22 ?  79   GLY B H    1 
ATOM   6722  H HA2  . GLY B 1 113 ? -11.654 47.653  31.411 1.00 16.14 ?  79   GLY B HA2  1 
ATOM   6723  H HA3  . GLY B 1 113 ? -10.941 46.283  31.745 1.00 16.14 ?  79   GLY B HA3  1 
ATOM   6724  N N    . THR B 1 114 ? -9.692  47.621  33.906 1.00 13.03 ?  80   THR B N    1 
ATOM   6725  C CA   . THR B 1 114 ? -9.561  48.094  35.282 1.00 12.87 ?  80   THR B CA   1 
ATOM   6726  C C    . THR B 1 114 ? -9.932  49.578  35.374 1.00 12.70 ?  80   THR B C    1 
ATOM   6727  O O    . THR B 1 114 ? -10.665 49.979  36.276 1.00 13.85 ?  80   THR B O    1 
ATOM   6728  C CB   . THR B 1 114 ? -8.123  47.868  35.752 1.00 11.96 ?  80   THR B CB   1 
ATOM   6729  O OG1  . THR B 1 114 ? -7.846  46.453  35.773 1.00 12.90 ?  80   THR B OG1  1 
ATOM   6730  C CG2  . THR B 1 114 ? -7.889  48.423  37.140 1.00 13.28 ?  80   THR B CG2  1 
ATOM   6731  H H    . THR B 1 114 ? -8.953  47.365  33.550 1.00 15.63 ?  80   THR B H    1 
ATOM   6732  H HA   . THR B 1 114 ? -10.158 47.595  35.862 1.00 15.45 ?  80   THR B HA   1 
ATOM   6733  H HB   . THR B 1 114 ? -7.524  48.326  35.142 1.00 14.35 ?  80   THR B HB   1 
ATOM   6734  H HG1  . THR B 1 114 ? -7.963  46.126  35.008 1.00 15.48 ?  80   THR B HG1  1 
ATOM   6735  H HG21 . THR B 1 114 ? -6.971  48.265  37.410 1.00 15.93 ?  80   THR B HG21 1 
ATOM   6736  H HG22 . THR B 1 114 ? -8.060  49.378  37.148 1.00 15.93 ?  80   THR B HG22 1 
ATOM   6737  H HG23 . THR B 1 114 ? -8.483  47.992  37.775 1.00 15.93 ?  80   THR B HG23 1 
ATOM   6738  N N    . LEU B 1 115 ? -9.418  50.389  34.461 1.00 12.46 ?  81   LEU B N    1 
ATOM   6739  C CA   . LEU B 1 115 ? -9.700  51.825  34.492 1.00 13.43 ?  81   LEU B CA   1 
ATOM   6740  C C    . LEU B 1 115 ? -11.180 52.084  34.327 1.00 13.52 ?  81   LEU B C    1 
ATOM   6741  O O    . LEU B 1 115 ? -11.756 52.889  35.071 1.00 13.88 ?  81   LEU B O    1 
ATOM   6742  C CB   . LEU B 1 115 ? -8.896  52.547  33.408 1.00 15.23 ?  81   LEU B CB   1 
ATOM   6743  C CG   . LEU B 1 115 ? -7.407  52.628  33.677 1.00 14.79 ?  81   LEU B CG   1 
ATOM   6744  C CD1  . LEU B 1 115 ? -6.743  53.175  32.445 1.00 18.95 ?  81   LEU B CD1  1 
ATOM   6745  C CD2  . LEU B 1 115 ? -7.069  53.450  34.898 1.00 15.35 ?  81   LEU B CD2  1 
ATOM   6746  H H    . LEU B 1 115 ? -8.905  50.140  33.817 1.00 14.95 ?  81   LEU B H    1 
ATOM   6747  H HA   . LEU B 1 115 ? -9.422  52.184  35.349 1.00 16.11 ?  81   LEU B HA   1 
ATOM   6748  H HB2  . LEU B 1 115 ? -9.018  52.077  32.568 1.00 18.28 ?  81   LEU B HB2  1 
ATOM   6749  H HB3  . LEU B 1 115 ? -9.230  53.455  33.330 1.00 18.28 ?  81   LEU B HB3  1 
ATOM   6750  H HG   . LEU B 1 115 ? -7.068  51.741  33.875 1.00 17.75 ?  81   LEU B HG   1 
ATOM   6751  H HD11 . LEU B 1 115 ? -5.785  53.206  32.590 1.00 22.74 ?  81   LEU B HD11 1 
ATOM   6752  H HD12 . LEU B 1 115 ? -6.946  52.595  31.693 1.00 22.74 ?  81   LEU B HD12 1 
ATOM   6753  H HD13 . LEU B 1 115 ? -7.081  54.068  32.274 1.00 22.74 ?  81   LEU B HD13 1 
ATOM   6754  H HD21 . LEU B 1 115 ? -6.106  53.472  35.007 1.00 18.42 ?  81   LEU B HD21 1 
ATOM   6755  H HD22 . LEU B 1 115 ? -7.409  54.350  34.776 1.00 18.42 ?  81   LEU B HD22 1 
ATOM   6756  H HD23 . LEU B 1 115 ? -7.481  53.043  35.676 1.00 18.42 ?  81   LEU B HD23 1 
ATOM   6757  N N    . ALA B 1 116 ? -11.835 51.382  33.407 1.00 12.51 ?  82   ALA B N    1 
ATOM   6758  C CA   . ALA B 1 116 ? -13.255 51.601  33.172 1.00 14.09 ?  82   ALA B CA   1 
ATOM   6759  C C    . ALA B 1 116 ? -14.067 51.185  34.376 1.00 13.90 ?  82   ALA B C    1 
ATOM   6760  O O    . ALA B 1 116 ? -14.970 51.902  34.836 1.00 15.31 ?  82   ALA B O    1 
ATOM   6761  C CB   . ALA B 1 116 ? -13.695 50.835  31.938 1.00 14.19 ?  82   ALA B CB   1 
ATOM   6762  H H    . ALA B 1 116 ? -11.483 50.777  32.909 1.00 15.01 ?  82   ALA B H    1 
ATOM   6763  H HA   . ALA B 1 116 ? -13.410 52.546  33.013 1.00 16.90 ?  82   ALA B HA   1 
ATOM   6764  H HB1  . ALA B 1 116 ? -14.653 50.939  31.826 1.00 17.02 ?  82   ALA B HB1  1 
ATOM   6765  H HB2  . ALA B 1 116 ? -13.231 51.191  31.164 1.00 17.02 ?  82   ALA B HB2  1 
ATOM   6766  H HB3  . ALA B 1 116 ? -13.475 49.897  32.053 1.00 17.02 ?  82   ALA B HB3  1 
ATOM   6767  N N    . THR B 1 117 ? -13.749 50.017  34.937 1.00 13.59 ?  83   THR B N    1 
ATOM   6768  C CA   . THR B 1 117 ? -14.497 49.498  36.077 1.00 12.75 ?  83   THR B CA   1 
ATOM   6769  C C    . THR B 1 117 ? -14.344 50.413  37.276 1.00 12.74 ?  83   THR B C    1 
ATOM   6770  O O    . THR B 1 117 ? -15.326 50.730  37.973 1.00 13.33 ?  83   THR B O    1 
ATOM   6771  C CB   . THR B 1 117 ? -13.990 48.092  36.399 1.00 13.21 ?  83   THR B CB   1 
ATOM   6772  O OG1  . THR B 1 117 ? -14.258 47.243  35.273 1.00 13.95 ?  83   THR B OG1  1 
ATOM   6773  C CG2  . THR B 1 117 ? -14.683 47.554  37.610 1.00 13.16 ?  83   THR B CG2  1 
ATOM   6774  H H    . THR B 1 117 ? -13.106 49.509  34.677 1.00 16.31 ?  83   THR B H    1 
ATOM   6775  H HA   . THR B 1 117 ? -15.441 49.446  35.858 1.00 15.30 ?  83   THR B HA   1 
ATOM   6776  H HB   . THR B 1 117 ? -13.037 48.109  36.581 1.00 15.86 ?  83   THR B HB   1 
ATOM   6777  H HG1  . THR B 1 117 ? -13.685 47.373  34.672 1.00 16.74 ?  83   THR B HG1  1 
ATOM   6778  H HG21 . THR B 1 117 ? -14.345 46.670  37.821 1.00 15.79 ?  83   THR B HG21 1 
ATOM   6779  H HG22 . THR B 1 117 ? -14.529 48.139  38.368 1.00 15.79 ?  83   THR B HG22 1 
ATOM   6780  H HG23 . THR B 1 117 ? -15.638 47.494  37.447 1.00 15.79 ?  83   THR B HG23 1 
ATOM   6781  N N    . ALA B 1 118 ? -13.108 50.794  37.579 1.00 12.78 ?  84   ALA B N    1 
ATOM   6782  C CA   . ALA B 1 118 ? -12.862 51.644  38.732 1.00 11.56 ?  84   ALA B CA   1 
ATOM   6783  C C    . ALA B 1 118 ? -13.570 52.989  38.586 1.00 13.92 ?  84   ALA B C    1 
ATOM   6784  O O    . ALA B 1 118 ? -14.106 53.522  39.572 1.00 13.27 ?  84   ALA B O    1 
ATOM   6785  C CB   . ALA B 1 118 ? -11.368 51.835  38.955 1.00 13.54 ?  84   ALA B CB   1 
ATOM   6786  H H    . ALA B 1 118 ? -12.403 50.577  37.137 1.00 15.34 ?  84   ALA B H    1 
ATOM   6787  H HA   . ALA B 1 118 ? -13.215 51.201  39.519 1.00 13.87 ?  84   ALA B HA   1 
ATOM   6788  H HB1  . ALA B 1 118 ? -11.235 52.476  39.670 1.00 16.25 ?  84   ALA B HB1  1 
ATOM   6789  H HB2  . ALA B 1 118 ? -10.973 50.982  39.197 1.00 16.25 ?  84   ALA B HB2  1 
ATOM   6790  H HB3  . ALA B 1 118 ? -10.965 52.164  38.136 1.00 16.25 ?  84   ALA B HB3  1 
ATOM   6791  N N    . SER B 1 119 ? -13.553 53.569  37.383 1.00 14.16 ?  85   SER B N    1 
ATOM   6792  C CA   . SER B 1 119 ? -14.235 54.849  37.189 1.00 13.78 ?  85   SER B CA   1 
ATOM   6793  C C    . SER B 1 119 ? -15.715 54.714  37.472 1.00 15.29 ?  85   SER B C    1 
ATOM   6794  O O    . SER B 1 119 ? -16.304 55.573  38.143 1.00 13.69 ?  85   SER B O    1 
ATOM   6795  C CB   . SER B 1 119 ? -13.962 55.324  35.782 1.00 14.59 ?  85   SER B CB   1 
ATOM   6796  O OG   . SER B 1 119 ? -14.566 56.609  35.594 1.00 17.85 ?  85   SER B OG   1 
ATOM   6797  H H    . SER B 1 119 ? -13.165 53.252  36.684 1.00 17.00 ?  85   SER B H    1 
ATOM   6798  H HA   . SER B 1 119 ? -13.895 55.521  37.802 1.00 16.53 ?  85   SER B HA   1 
ATOM   6799  H HB2  . SER B 1 119 ? -13.004 55.395  35.645 1.00 17.51 ?  85   SER B HB2  1 
ATOM   6800  H HB3  . SER B 1 119 ? -14.342 54.694  35.149 1.00 17.51 ?  85   SER B HB3  1 
ATOM   6801  H HG   . SER B 1 119 ? -15.394 56.524  35.484 1.00 21.42 ?  85   SER B HG   1 
ATOM   6802  N N    . ALA B 1 120 ? -16.326 53.630  37.008 1.00 13.16 ?  86   ALA B N    1 
ATOM   6803  C CA   . ALA B 1 120 ? -17.752 53.408  37.216 1.00 12.93 ?  86   ALA B CA   1 
ATOM   6804  C C    . ALA B 1 120 ? -18.064 53.179  38.691 1.00 14.62 ?  86   ALA B C    1 
ATOM   6805  O O    . ALA B 1 120 ? -19.066 53.691  39.215 1.00 14.33 ?  86   ALA B O    1 
ATOM   6806  C CB   . ALA B 1 120 ? -18.217 52.235  36.364 1.00 14.70 ?  86   ALA B CB   1 
ATOM   6807  H H    . ALA B 1 120 ? -15.937 53.003  36.566 1.00 15.79 ?  86   ALA B H    1 
ATOM   6808  H HA   . ALA B 1 120 ? -18.245 54.194  36.932 1.00 15.52 ?  86   ALA B HA   1 
ATOM   6809  H HB1  . ALA B 1 120 ? -19.155 52.067  36.544 1.00 17.64 ?  86   ALA B HB1  1 
ATOM   6810  H HB2  . ALA B 1 120 ? -18.095 52.456  35.428 1.00 17.64 ?  86   ALA B HB2  1 
ATOM   6811  H HB3  . ALA B 1 120 ? -17.691 51.452  36.591 1.00 17.64 ?  86   ALA B HB3  1 
ATOM   6812  N N    . ILE B 1 121 ? -17.238 52.380  39.393 1.00 12.77 ?  87   ILE B N    1 
ATOM   6813  C CA   . ILE B 1 121 ? -17.454 52.149  40.828 1.00 12.99 ?  87   ILE B CA   1 
ATOM   6814  C C    . ILE B 1 121 ? -17.416 53.478  41.569 1.00 14.01 ?  87   ILE B C    1 
ATOM   6815  O O    . ILE B 1 121 ? -18.285 53.790  42.401 1.00 13.62 ?  87   ILE B O    1 
ATOM   6816  C CB   . ILE B 1 121 ? -16.385 51.175  41.395 1.00 13.51 ?  87   ILE B CB   1 
ATOM   6817  C CG1  . ILE B 1 121 ? -16.572 49.767  40.840 1.00 13.74 ?  87   ILE B CG1  1 
ATOM   6818  C CG2  . ILE B 1 121 ? -16.427 51.169  42.924 1.00 13.59 ?  87   ILE B CG2  1 
ATOM   6819  C CD1  . ILE B 1 121 ? -15.401 48.810  41.183 1.00 13.89 ?  87   ILE B CD1  1 
ATOM   6820  H H    . ILE B 1 121 ? -16.558 51.969  39.065 1.00 15.33 ?  87   ILE B H    1 
ATOM   6821  H HA   . ILE B 1 121 ? -18.326 51.741  40.948 1.00 15.58 ?  87   ILE B HA   1 
ATOM   6822  H HB   . ILE B 1 121 ? -15.513 51.490  41.110 1.00 16.21 ?  87   ILE B HB   1 
ATOM   6823  H HG12 . ILE B 1 121 ? -17.384 49.390  41.212 1.00 16.49 ?  87   ILE B HG12 1 
ATOM   6824  H HG13 . ILE B 1 121 ? -16.642 49.818  39.874 1.00 16.49 ?  87   ILE B HG13 1 
ATOM   6825  H HG21 . ILE B 1 121 ? -15.896 50.426  43.251 1.00 16.31 ?  87   ILE B HG21 1 
ATOM   6826  H HG22 . ILE B 1 121 ? -16.063 52.005  43.253 1.00 16.31 ?  87   ILE B HG22 1 
ATOM   6827  H HG23 . ILE B 1 121 ? -17.347 51.071  43.214 1.00 16.31 ?  87   ILE B HG23 1 
ATOM   6828  H HD11 . ILE B 1 121 ? -15.427 48.051  40.579 1.00 16.67 ?  87   ILE B HD11 1 
ATOM   6829  H HD12 . ILE B 1 121 ? -14.563 49.287  41.080 1.00 16.67 ?  87   ILE B HD12 1 
ATOM   6830  H HD13 . ILE B 1 121 ? -15.499 48.507  42.099 1.00 16.67 ?  87   ILE B HD13 1 
ATOM   6831  N N    . LYS B 1 122 ? -16.385 54.270  41.296 1.00 13.58 ?  88   LYS B N    1 
ATOM   6832  C CA   . LYS B 1 122 ? -16.224 55.522  42.031 1.00 13.62 ?  88   LYS B CA   1 
ATOM   6833  C C    . LYS B 1 122 ? -17.341 56.527  41.730 1.00 15.99 ?  88   LYS B C    1 
ATOM   6834  O O    . LYS B 1 122 ? -17.668 57.332  42.599 1.00 16.40 ?  88   LYS B O    1 
ATOM   6835  C CB   . LYS B 1 122 ? -14.883 56.162  41.689 1.00 13.81 ?  88   LYS B CB   1 
ATOM   6836  C CG   . LYS B 1 122 ? -13.649 55.419  42.244 1.00 15.13 ?  88   LYS B CG   1 
ATOM   6837  C CD   . LYS B 1 122 ? -13.538 55.598  43.753 1.00 19.24 ?  88   LYS B CD   1 
ATOM   6838  C CE   . LYS B 1 122 ? -12.195 55.043  44.276 1.00 19.36 ?  88   LYS B CE   1 
ATOM   6839  N NZ   . LYS B 1 122 ? -11.984 55.462  45.661 1.00 20.28 ?  88   LYS B NZ   1 
ATOM   6840  H H    . LYS B 1 122 ? -15.779 54.112  40.706 1.00 16.30 ?  88   LYS B H    1 
ATOM   6841  H HA   . LYS B 1 122 ? -16.248 55.310  42.977 1.00 16.34 ?  88   LYS B HA   1 
ATOM   6842  H HB2  . LYS B 1 122 ? -14.794 56.194  40.724 1.00 16.57 ?  88   LYS B HB2  1 
ATOM   6843  H HB3  . LYS B 1 122 ? -14.870 57.061  42.053 1.00 16.57 ?  88   LYS B HB3  1 
ATOM   6844  H HG2  . LYS B 1 122 ? -13.728 54.472  42.052 1.00 18.16 ?  88   LYS B HG2  1 
ATOM   6845  H HG3  . LYS B 1 122 ? -12.845 55.775  41.834 1.00 18.16 ?  88   LYS B HG3  1 
ATOM   6846  H HD2  . LYS B 1 122 ? -13.587 56.541  43.972 1.00 23.09 ?  88   LYS B HD2  1 
ATOM   6847  H HD3  . LYS B 1 122 ? -14.260 55.118  44.189 1.00 23.09 ?  88   LYS B HD3  1 
ATOM   6848  H HE2  . LYS B 1 122 ? -12.207 54.074  44.243 1.00 23.24 ?  88   LYS B HE2  1 
ATOM   6849  H HE3  . LYS B 1 122 ? -11.468 55.384  43.733 1.00 23.24 ?  88   LYS B HE3  1 
ATOM   6850  H HZ1  . LYS B 1 122 ? -11.200 55.158  45.954 1.00 24.33 ?  88   LYS B HZ1  1 
ATOM   6851  H HZ2  . LYS B 1 122 ? -11.988 56.350  45.714 1.00 24.33 ?  88   LYS B HZ2  1 
ATOM   6852  H HZ3  . LYS B 1 122 ? -12.631 55.138  46.179 1.00 24.33 ?  88   LYS B HZ3  1 
ATOM   6853  N N    . LEU B 1 123 ? -17.922 56.492  40.534 1.00 13.84 ?  89   LEU B N    1 
ATOM   6854  C CA   . LEU B 1 123 ? -19.054 57.375  40.240 1.00 14.49 ?  89   LEU B CA   1 
ATOM   6855  C C    . LEU B 1 123 ? -20.247 57.022  41.099 1.00 17.47 ?  89   LEU B C    1 
ATOM   6856  O O    . LEU B 1 123 ? -21.004 57.913  41.527 1.00 17.22 ?  89   LEU B O    1 
ATOM   6857  C CB   . LEU B 1 123 ? -19.370 57.282  38.748 1.00 16.85 ?  89   LEU B CB   1 
ATOM   6858  C CG   . LEU B 1 123 ? -20.466 58.241  38.225 1.00 14.20 ?  89   LEU B CG   1 
ATOM   6859  C CD1  . LEU B 1 123 ? -20.131 59.681  38.471 1.00 14.93 ?  89   LEU B CD1  1 
ATOM   6860  C CD2  . LEU B 1 123 ? -20.657 58.019  36.752 1.00 16.81 ?  89   LEU B CD2  1 
ATOM   6861  H H    . LEU B 1 123 ? -17.687 55.978  39.886 1.00 16.61 ?  89   LEU B H    1 
ATOM   6862  H HA   . LEU B 1 123 ? -18.833 58.300  40.435 1.00 17.39 ?  89   LEU B HA   1 
ATOM   6863  H HB2  . LEU B 1 123 ? -18.558 57.477  38.254 1.00 20.22 ?  89   LEU B HB2  1 
ATOM   6864  H HB3  . LEU B 1 123 ? -19.666 56.378  38.558 1.00 20.22 ?  89   LEU B HB3  1 
ATOM   6865  H HG   . LEU B 1 123 ? -21.287 58.053  38.705 1.00 17.04 ?  89   LEU B HG   1 
ATOM   6866  H HD11 . LEU B 1 123 ? -20.816 60.238  38.069 1.00 17.91 ?  89   LEU B HD11 1 
ATOM   6867  H HD12 . LEU B 1 123 ? -20.096 59.837  39.428 1.00 17.91 ?  89   LEU B HD12 1 
ATOM   6868  H HD13 . LEU B 1 123 ? -19.269 59.877  38.073 1.00 17.91 ?  89   LEU B HD13 1 
ATOM   6869  H HD21 . LEU B 1 123 ? -21.324 58.641  36.422 1.00 20.17 ?  89   LEU B HD21 1 
ATOM   6870  H HD22 . LEU B 1 123 ? -19.813 58.168  36.297 1.00 20.17 ?  89   LEU B HD22 1 
ATOM   6871  H HD23 . LEU B 1 123 ? -20.955 57.107  36.606 1.00 20.17 ?  89   LEU B HD23 1 
ATOM   6872  N N    . LYS B 1 124 ? -20.442 55.741  41.390 1.00 14.49 ?  90   LYS B N    1 
ATOM   6873  C CA   . LYS B 1 124 ? -21.536 55.314  42.250 1.00 14.37 ?  90   LYS B CA   1 
ATOM   6874  C C    . LYS B 1 124 ? -21.230 55.542  43.719 1.00 16.99 ?  90   LYS B C    1 
ATOM   6875  O O    . LYS B 1 124 ? -22.121 55.949  44.501 1.00 19.16 ?  90   LYS B O    1 
ATOM   6876  C CB   . LYS B 1 124 ? -21.848 53.839  41.992 1.00 17.35 ?  90   LYS B CB   1 
ATOM   6877  C CG   . LYS B 1 124 ? -22.921 53.246  42.852 1.00 23.21 ?  90   LYS B CG   1 
ATOM   6878  C CD   . LYS B 1 124 ? -24.236 54.023  42.783 1.00 30.87 ?  90   LYS B CD   1 
ATOM   6879  C CE   . LYS B 1 124 ? -25.327 53.269  43.560 1.00 37.52 ?  90   LYS B CE   1 
ATOM   6880  N NZ   . LYS B 1 124 ? -26.610 54.056  43.564 1.00 38.44 ?  90   LYS B NZ   1 
ATOM   6881  H H    . LYS B 1 124 ? -19.953 55.096  41.100 1.00 17.39 ?  90   LYS B H    1 
ATOM   6882  H HA   . LYS B 1 124 ? -22.324 55.836  42.032 1.00 17.25 ?  90   LYS B HA   1 
ATOM   6883  H HB2  . LYS B 1 124 ? -22.132 53.744  41.069 1.00 20.82 ?  90   LYS B HB2  1 
ATOM   6884  H HB3  . LYS B 1 124 ? -21.039 53.325  42.145 1.00 20.82 ?  90   LYS B HB3  1 
ATOM   6885  H HG2  . LYS B 1 124 ? -23.095 52.338  42.558 1.00 27.85 ?  90   LYS B HG2  1 
ATOM   6886  H HG3  . LYS B 1 124 ? -22.623 53.245  43.774 1.00 27.85 ?  90   LYS B HG3  1 
ATOM   6887  H HD2  . LYS B 1 124 ? -24.119 54.900  43.181 1.00 37.05 ?  90   LYS B HD2  1 
ATOM   6888  H HD3  . LYS B 1 124 ? -24.516 54.113  41.859 1.00 37.05 ?  90   LYS B HD3  1 
ATOM   6889  H HE2  . LYS B 1 124 ? -25.492 52.411  43.138 1.00 45.02 ?  90   LYS B HE2  1 
ATOM   6890  H HE3  . LYS B 1 124 ? -25.041 53.138  44.477 1.00 45.02 ?  90   LYS B HE3  1 
ATOM   6891  H HZ1  . LYS B 1 124 ? -27.240 53.609  44.005 1.00 46.13 ?  90   LYS B HZ1  1 
ATOM   6892  H HZ2  . LYS B 1 124 ? -26.483 54.843  43.960 1.00 46.13 ?  90   LYS B HZ2  1 
ATOM   6893  H HZ3  . LYS B 1 124 ? -26.885 54.195  42.728 1.00 46.13 ?  90   LYS B HZ3  1 
ATOM   6894  N N    . ASN B 1 125 ? -19.994 55.283  44.164 1.00 15.37 ?  91   ASN B N    1 
ATOM   6895  C CA   . ASN B 1 125 ? -19.619 55.474  45.565 1.00 14.87 ?  91   ASN B CA   1 
ATOM   6896  C C    . ASN B 1 125 ? -18.156 55.899  45.612 1.00 16.71 ?  91   ASN B C    1 
ATOM   6897  O O    . ASN B 1 125 ? -17.259 55.059  45.523 1.00 14.58 ?  91   ASN B O    1 
ATOM   6898  C CB   . ASN B 1 125 ? -19.806 54.218  46.395 1.00 16.50 ?  91   ASN B CB   1 
ATOM   6899  C CG   . ASN B 1 125 ? -19.665 54.487  47.872 1.00 18.35 ?  91   ASN B CG   1 
ATOM   6900  O OD1  . ASN B 1 125 ? -19.071 55.467  48.292 1.00 17.55 ?  91   ASN B OD1  1 
ATOM   6901  N ND2  . ASN B 1 125 ? -20.285 53.633  48.687 1.00 26.25 ?  91   ASN B ND2  1 
ATOM   6902  H H    . ASN B 1 125 ? -19.352 54.995  43.669 1.00 18.44 ?  91   ASN B H    1 
ATOM   6903  H HA   . ASN B 1 125 ? -20.183 56.179  45.920 1.00 17.84 ?  91   ASN B HA   1 
ATOM   6904  H HB2  . ASN B 1 125 ? -20.693 53.861  46.236 1.00 19.79 ?  91   ASN B HB2  1 
ATOM   6905  H HB3  . ASN B 1 125 ? -19.135 53.566  46.141 1.00 19.79 ?  91   ASN B HB3  1 
ATOM   6906  H HD21 . ASN B 1 125 ? -20.733 52.975  48.361 1.00 31.51 ?  91   ASN B HD21 1 
ATOM   6907  H HD22 . ASN B 1 125 ? -20.237 53.741  49.539 1.00 31.51 ?  91   ASN B HD22 1 
ATOM   6908  N N    . ASN B 1 126 ? -17.899 57.188  45.799 1.00 15.80 ?  92   ASN B N    1 
ATOM   6909  C CA   . ASN B 1 126 ? -16.519 57.611  45.741 1.00 16.17 ?  92   ASN B CA   1 
ATOM   6910  C C    . ASN B 1 126 ? -15.719 57.187  46.962 1.00 16.24 ?  92   ASN B C    1 
ATOM   6911  O O    . ASN B 1 126 ? -14.489 57.271  46.925 1.00 18.87 ?  92   ASN B O    1 
ATOM   6912  C CB   . ASN B 1 126 ? -16.376 59.094  45.362 1.00 25.41 ?  92   ASN B CB   1 
ATOM   6913  C CG   . ASN B 1 126 ? -16.951 60.018  46.375 1.00 27.39 ?  92   ASN B CG   1 
ATOM   6914  O OD1  . ASN B 1 126 ? -16.498 60.054  47.517 1.00 38.48 ?  92   ASN B OD1  1 
ATOM   6915  N ND2  . ASN B 1 126 ? -17.914 60.864  45.947 1.00 24.61 ?  92   ASN B ND2  1 
ATOM   6916  H H    . ASN B 1 126 ? -18.481 57.802  45.954 1.00 18.95 ?  92   ASN B H    1 
ATOM   6917  H HA   . ASN B 1 126 ? -16.087 57.168  44.994 1.00 19.41 ?  92   ASN B HA   1 
ATOM   6918  H HB2  . ASN B 1 126 ? -15.434 59.305  45.268 1.00 30.50 ?  92   ASN B HB2  1 
ATOM   6919  H HB3  . ASN B 1 126 ? -16.837 59.250  44.523 1.00 30.50 ?  92   ASN B HB3  1 
ATOM   6920  H HD21 . ASN B 1 126 ? -18.165 60.849  45.124 1.00 29.53 ?  92   ASN B HD21 1 
ATOM   6921  H HD22 . ASN B 1 126 ? -18.277 61.417  46.496 1.00 29.53 ?  92   ASN B HD22 1 
ATOM   6922  N N    . LYS B 1 127 ? -16.379 56.698  48.001 1.00 15.08 ?  93   LYS B N    1 
ATOM   6923  C CA   . LYS B 1 127 ? -15.705 56.284  49.216 1.00 15.23 ?  93   LYS B CA   1 
ATOM   6924  C C    . LYS B 1 127 ? -15.224 54.826  49.166 1.00 15.28 ?  93   LYS B C    1 
ATOM   6925  O O    . LYS B 1 127 ? -14.407 54.434  50.005 1.00 16.51 ?  93   LYS B O    1 
ATOM   6926  C CB   . LYS B 1 127 ? -16.662 56.444  50.394 1.00 18.31 ?  93   LYS B CB   1 
ATOM   6927  C CG   . LYS B 1 127 ? -16.989 57.915  50.724 1.00 20.71 ?  93   LYS B CG   1 
ATOM   6928  C CD   . LYS B 1 127 ? -17.590 58.071  52.107 1.00 37.87 ?  93   LYS B CD   1 
ATOM   6929  C CE   . LYS B 1 127 ? -18.066 59.525  52.310 1.00 53.33 ?  93   LYS B CE   1 
ATOM   6930  N NZ   . LYS B 1 127 ? -19.450 59.628  52.854 1.00 59.50 ?  93   LYS B NZ   1 
ATOM   6931  H H    . LYS B 1 127 ? -17.233 56.595  48.026 1.00 18.09 ?  93   LYS B H    1 
ATOM   6932  H HA   . LYS B 1 127 ? -14.930 56.848  49.358 1.00 18.27 ?  93   LYS B HA   1 
ATOM   6933  H HB2  . LYS B 1 127 ? -17.495 55.994  50.184 1.00 21.97 ?  93   LYS B HB2  1 
ATOM   6934  H HB3  . LYS B 1 127 ? -16.259 56.045  51.181 1.00 21.97 ?  93   LYS B HB3  1 
ATOM   6935  H HG2  . LYS B 1 127 ? -16.174 58.438  50.688 1.00 24.85 ?  93   LYS B HG2  1 
ATOM   6936  H HG3  . LYS B 1 127 ? -17.629 58.252  50.078 1.00 24.85 ?  93   LYS B HG3  1 
ATOM   6937  H HD2  . LYS B 1 127 ? -18.351 57.477  52.203 1.00 45.44 ?  93   LYS B HD2  1 
ATOM   6938  H HD3  . LYS B 1 127 ? -16.922 57.865  52.780 1.00 45.44 ?  93   LYS B HD3  1 
ATOM   6939  H HE2  . LYS B 1 127 ? -17.469 59.966  52.935 1.00 64.00 ?  93   LYS B HE2  1 
ATOM   6940  H HE3  . LYS B 1 127 ? -18.048 59.983  51.455 1.00 64.00 ?  93   LYS B HE3  1 
ATOM   6941  H HZ1  . LYS B 1 127 ? -19.676 60.484  52.949 1.00 71.40 ?  93   LYS B HZ1  1 
ATOM   6942  H HZ2  . LYS B 1 127 ? -20.025 59.238  52.298 1.00 71.40 ?  93   LYS B HZ2  1 
ATOM   6943  H HZ3  . LYS B 1 127 ? -19.496 59.227  53.647 1.00 71.40 ?  93   LYS B HZ3  1 
ATOM   6944  N N    . ALA B 1 128 ? -15.696 54.030  48.196 1.00 14.49 ?  94   ALA B N    1 
ATOM   6945  C CA   . ALA B 1 128 ? -15.227 52.657  48.024 1.00 14.09 ?  94   ALA B CA   1 
ATOM   6946  C C    . ALA B 1 128 ? -13.744 52.687  47.677 1.00 14.88 ?  94   ALA B C    1 
ATOM   6947  O O    . ALA B 1 128 ? -13.296 53.522  46.888 1.00 18.59 ?  94   ALA B O    1 
ATOM   6948  C CB   . ALA B 1 128 ? -15.982 52.000  46.873 1.00 15.31 ?  94   ALA B CB   1 
ATOM   6949  H H    . ALA B 1 128 ? -16.292 54.267  47.622 1.00 17.39 ?  94   ALA B H    1 
ATOM   6950  H HA   . ALA B 1 128 ? -15.374 52.144  48.834 1.00 16.90 ?  94   ALA B HA   1 
ATOM   6951  H HB1  . ALA B 1 128 ? -15.693 51.078  46.791 1.00 18.37 ?  94   ALA B HB1  1 
ATOM   6952  H HB2  . ALA B 1 128 ? -16.934 52.033  47.060 1.00 18.37 ?  94   ALA B HB2  1 
ATOM   6953  H HB3  . ALA B 1 128 ? -15.790 52.482  46.053 1.00 18.37 ?  94   ALA B HB3  1 
ATOM   6954  N N    . LYS B 1 129 ? -12.933 51.816  48.292 1.00 13.41 ?  95   LYS B N    1 
ATOM   6955  C CA   . LYS B 1 129 ? -11.515 51.732  47.955 1.00 13.35 ?  95   LYS B CA   1 
ATOM   6956  C C    . LYS B 1 129 ? -11.292 50.585  46.970 1.00 11.46 ?  95   LYS B C    1 
ATOM   6957  O O    . LYS B 1 129 ? -11.794 49.474  47.195 1.00 13.16 ?  95   LYS B O    1 
ATOM   6958  C CB   . LYS B 1 129 ? -10.647 51.510  49.197 1.00 13.48 ?  95   LYS B CB   1 
ATOM   6959  C CG   . LYS B 1 129 ? -10.649 52.659  50.191 1.00 13.74 ?  95   LYS B CG   1 
ATOM   6960  C CD   . LYS B 1 129 ? -10.057 53.905  49.614 1.00 15.39 ?  95   LYS B CD   1 
ATOM   6961  C CE   . LYS B 1 129 ? -9.918  54.953  50.733 1.00 19.13 ?  95   LYS B CE   1 
ATOM   6962  N NZ   . LYS B 1 129 ? -9.222  56.134  50.211 1.00 21.44 ?  95   LYS B NZ   1 
ATOM   6963  H H    . LYS B 1 129 ? -13.185 51.268  48.905 1.00 16.09 ?  95   LYS B H    1 
ATOM   6964  H HA   . LYS B 1 129 ? -11.245 52.568  47.542 1.00 16.02 ?  95   LYS B HA   1 
ATOM   6965  H HB2  . LYS B 1 129 ? -10.972 50.723  49.662 1.00 16.17 ?  95   LYS B HB2  1 
ATOM   6966  H HB3  . LYS B 1 129 ? -9.731  51.373  48.912 1.00 16.17 ?  95   LYS B HB3  1 
ATOM   6967  H HG2  . LYS B 1 129 ? -11.563 52.853  50.453 1.00 16.49 ?  95   LYS B HG2  1 
ATOM   6968  H HG3  . LYS B 1 129 ? -10.127 52.409  50.969 1.00 16.49 ?  95   LYS B HG3  1 
ATOM   6969  H HD2  . LYS B 1 129 ? -9.179  53.716  49.248 1.00 18.47 ?  95   LYS B HD2  1 
ATOM   6970  H HD3  . LYS B 1 129 ? -10.637 54.258  48.921 1.00 18.47 ?  95   LYS B HD3  1 
ATOM   6971  H HE2  . LYS B 1 129 ? -10.797 55.220  51.046 1.00 22.95 ?  95   LYS B HE2  1 
ATOM   6972  H HE3  . LYS B 1 129 ? -9.403  54.584  51.468 1.00 22.95 ?  95   LYS B HE3  1 
ATOM   6973  H HZ1  . LYS B 1 129 ? -9.144  56.749  50.850 1.00 25.73 ?  95   LYS B HZ1  1 
ATOM   6974  H HZ2  . LYS B 1 129 ? -8.409  55.908  49.928 1.00 25.73 ?  95   LYS B HZ2  1 
ATOM   6975  H HZ3  . LYS B 1 129 ? -9.679  56.480  49.531 1.00 25.73 ?  95   LYS B HZ3  1 
ATOM   6976  N N    . VAL B 1 130 ? -10.554 50.865  45.898 1.00 12.60 ?  96   VAL B N    1 
ATOM   6977  C CA   . VAL B 1 130 ? -10.382 49.932  44.791 1.00 11.04 ?  96   VAL B CA   1 
ATOM   6978  C C    . VAL B 1 130 ? -8.897  49.666  44.646 1.00 12.01 ?  96   VAL B C    1 
ATOM   6979  O O    . VAL B 1 130 ? -8.086  50.600  44.478 1.00 13.51 ?  96   VAL B O    1 
ATOM   6980  C CB   . VAL B 1 130 ? -10.969 50.485  43.482 1.00 13.23 ?  96   VAL B CB   1 
ATOM   6981  C CG1  . VAL B 1 130 ? -10.746 49.511  42.333 1.00 12.94 ?  96   VAL B CG1  1 
ATOM   6982  C CG2  . VAL B 1 130 ? -12.469 50.811  43.607 1.00 14.83 ?  96   VAL B CG2  1 
ATOM   6983  H H    . VAL B 1 130 ? -10.135 51.608  45.789 1.00 15.12 ?  96   VAL B H    1 
ATOM   6984  H HA   . VAL B 1 130 ? -10.829 49.096  44.997 1.00 13.25 ?  96   VAL B HA   1 
ATOM   6985  H HB   . VAL B 1 130 ? -10.505 51.315  43.289 1.00 15.88 ?  96   VAL B HB   1 
ATOM   6986  H HG11 . VAL B 1 130 ? -11.295 49.779  41.580 1.00 15.52 ?  96   VAL B HG11 1 
ATOM   6987  H HG12 . VAL B 1 130 ? -9.809  49.528  42.082 1.00 15.52 ?  96   VAL B HG12 1 
ATOM   6988  H HG13 . VAL B 1 130 ? -10.994 48.619  42.623 1.00 15.52 ?  96   VAL B HG13 1 
ATOM   6989  H HG21 . VAL B 1 130 ? -12.818 51.034  42.730 1.00 17.80 ?  96   VAL B HG21 1 
ATOM   6990  H HG22 . VAL B 1 130 ? -12.932 50.035  43.960 1.00 17.80 ?  96   VAL B HG22 1 
ATOM   6991  H HG23 . VAL B 1 130 ? -12.580 51.564  44.209 1.00 17.80 ?  96   VAL B HG23 1 
ATOM   6992  N N    . LEU B 1 131 ? -8.525  48.367  44.715 1.00 12.28 ?  97   LEU B N    1 
ATOM   6993  C CA   . LEU B 1 131 ? -7.143  47.945  44.569 1.00 11.79 ?  97   LEU B CA   1 
ATOM   6994  C C    . LEU B 1 131 ? -6.912  47.243  43.236 1.00 11.65 ?  97   LEU B C    1 
ATOM   6995  O O    . LEU B 1 131 ? -7.758  46.471  42.763 1.00 12.78 ?  97   LEU B O    1 
ATOM   6996  C CB   . LEU B 1 131 ? -6.730  46.963  45.689 1.00 12.28 ?  97   LEU B CB   1 
ATOM   6997  C CG   . LEU B 1 131 ? -6.997  47.457  47.101 1.00 11.79 ?  97   LEU B CG   1 
ATOM   6998  C CD1  . LEU B 1 131 ? -6.531  46.385  48.112 1.00 13.14 ?  97   LEU B CD1  1 
ATOM   6999  C CD2  . LEU B 1 131 ? -6.322  48.778  47.425 1.00 13.46 ?  97   LEU B CD2  1 
ATOM   7000  H H    . LEU B 1 131 ? -9.072  47.718  44.847 1.00 14.73 ?  97   LEU B H    1 
ATOM   7001  H HA   . LEU B 1 131 ? -6.592  48.743  44.604 1.00 14.15 ?  97   LEU B HA   1 
ATOM   7002  H HB2  . LEU B 1 131 ? -7.224  46.136  45.571 1.00 14.74 ?  97   LEU B HB2  1 
ATOM   7003  H HB3  . LEU B 1 131 ? -5.778  46.794  45.614 1.00 14.74 ?  97   LEU B HB3  1 
ATOM   7004  H HG   . LEU B 1 131 ? -7.952  47.615  47.174 1.00 14.14 ?  97   LEU B HG   1 
ATOM   7005  H HD11 . LEU B 1 131 ? -6.621  46.739  49.011 1.00 15.76 ?  97   LEU B HD11 1 
ATOM   7006  H HD12 . LEU B 1 131 ? -7.083  45.594  48.010 1.00 15.76 ?  97   LEU B HD12 1 
ATOM   7007  H HD13 . LEU B 1 131 ? -5.603  46.166  47.933 1.00 15.76 ?  97   LEU B HD13 1 
ATOM   7008  H HD21 . LEU B 1 131 ? -6.592  49.062  48.312 1.00 16.15 ?  97   LEU B HD21 1 
ATOM   7009  H HD22 . LEU B 1 131 ? -5.360  48.657  47.396 1.00 16.15 ?  97   LEU B HD22 1 
ATOM   7010  H HD23 . LEU B 1 131 ? -6.591  49.440  46.770 1.00 16.15 ?  97   LEU B HD23 1 
ATOM   7011  N N    . TYR B 1 132 ? -5.728  47.480  42.663 1.00 11.17 ?  98   TYR B N    1 
ATOM   7012  C CA   . TYR B 1 132 ? -5.283  46.833  41.431 1.00 12.64 ?  98   TYR B CA   1 
ATOM   7013  C C    . TYR B 1 132 ? -4.425  45.614  41.765 1.00 10.00 ?  98   TYR B C    1 
ATOM   7014  O O    . TYR B 1 132 ? -3.357  45.741  42.381 1.00 11.28 ?  98   TYR B O    1 
ATOM   7015  C CB   . TYR B 1 132 ? -4.432  47.825  40.660 1.00 12.02 ?  98   TYR B CB   1 
ATOM   7016  C CG   . TYR B 1 132 ? -3.936  47.362  39.303 1.00 12.01 ?  98   TYR B CG   1 
ATOM   7017  C CD1  . TYR B 1 132 ? -4.818  46.891  38.385 1.00 12.33 ?  98   TYR B CD1  1 
ATOM   7018  C CD2  . TYR B 1 132 ? -2.604  47.443  38.970 1.00 11.91 ?  98   TYR B CD2  1 
ATOM   7019  C CE1  . TYR B 1 132 ? -4.385  46.541  37.132 1.00 12.33 ?  98   TYR B CE1  1 
ATOM   7020  C CE2  . TYR B 1 132 ? -2.157  47.087  37.722 1.00 12.41 ?  98   TYR B CE2  1 
ATOM   7021  C CZ   . TYR B 1 132 ? -3.071  46.644  36.808 1.00 12.54 ?  98   TYR B CZ   1 
ATOM   7022  O OH   . TYR B 1 132 ? -2.689  46.297  35.507 1.00 14.47 ?  98   TYR B OH   1 
ATOM   7023  H H    . TYR B 1 132 ? -5.149  48.030  42.981 1.00 13.41 ?  98   TYR B H    1 
ATOM   7024  H HA   . TYR B 1 132 ? -6.049  46.537  40.915 1.00 15.17 ?  98   TYR B HA   1 
ATOM   7025  H HB2  . TYR B 1 132 ? -4.959  48.626  40.514 1.00 14.43 ?  98   TYR B HB2  1 
ATOM   7026  H HB3  . TYR B 1 132 ? -3.650  48.034  41.195 1.00 14.43 ?  98   TYR B HB3  1 
ATOM   7027  H HD1  . TYR B 1 132 ? -5.717  46.805  38.606 1.00 14.79 ?  98   TYR B HD1  1 
ATOM   7028  H HD2  . TYR B 1 132 ? -1.993  47.746  39.603 1.00 14.29 ?  98   TYR B HD2  1 
ATOM   7029  H HE1  . TYR B 1 132 ? -4.995  46.231  36.501 1.00 14.79 ?  98   TYR B HE1  1 
ATOM   7030  H HE2  . TYR B 1 132 ? -1.255  47.145  37.504 1.00 14.90 ?  98   TYR B HE2  1 
ATOM   7031  H HH   . TYR B 1 132 ? -1.925  46.606  35.340 1.00 17.36 ?  98   TYR B HH   1 
ATOM   7032  N N    . TYR B 1 133 ? -4.863  44.447  41.325 1.00 10.88 ?  99   TYR B N    1 
ATOM   7033  C CA   . TYR B 1 133 ? -4.060  43.231  41.493 1.00 11.03 ?  99   TYR B CA   1 
ATOM   7034  C C    . TYR B 1 133 ? -2.759  43.343  40.695 1.00 10.92 ?  99   TYR B C    1 
ATOM   7035  O O    . TYR B 1 133 ? -2.741  43.766  39.537 1.00 11.32 ?  99   TYR B O    1 
ATOM   7036  C CB   . TYR B 1 133 ? -4.864  42.040  40.983 1.00 11.65 ?  99   TYR B CB   1 
ATOM   7037  C CG   . TYR B 1 133 ? -4.152  40.700  40.974 1.00 11.15 ?  99   TYR B CG   1 
ATOM   7038  C CD1  . TYR B 1 133 ? -3.387  40.327  39.884 1.00 10.64 ?  99   TYR B CD1  1 
ATOM   7039  C CD2  . TYR B 1 133 ? -4.256  39.848  42.055 1.00 11.69 ?  99   TYR B CD2  1 
ATOM   7040  C CE1  . TYR B 1 133 ? -2.761  39.100  39.855 1.00 11.38 ?  99   TYR B CE1  1 
ATOM   7041  C CE2  . TYR B 1 133 ? -3.627  38.568  42.029 1.00 11.47 ?  99   TYR B CE2  1 
ATOM   7042  C CZ   . TYR B 1 133 ? -2.872  38.265  40.930 1.00 11.06 ?  99   TYR B CZ   1 
ATOM   7043  O OH   . TYR B 1 133 ? -2.250  36.999  40.890 1.00 11.33 ?  99   TYR B OH   1 
ATOM   7044  H H    . TYR B 1 133 ? -5.616  44.324  40.928 1.00 13.06 ?  99   TYR B H    1 
ATOM   7045  H HA   . TYR B 1 133 ? -3.840  43.099  42.429 1.00 13.24 ?  99   TYR B HA   1 
ATOM   7046  H HB2  . TYR B 1 133 ? -5.648  41.942  41.546 1.00 13.98 ?  99   TYR B HB2  1 
ATOM   7047  H HB3  . TYR B 1 133 ? -5.132  42.226  40.070 1.00 13.98 ?  99   TYR B HB3  1 
ATOM   7048  H HD1  . TYR B 1 133 ? -3.295  40.909  39.165 1.00 12.77 ?  99   TYR B HD1  1 
ATOM   7049  H HD2  . TYR B 1 133 ? -4.740  40.110  42.805 1.00 14.03 ?  99   TYR B HD2  1 
ATOM   7050  H HE1  . TYR B 1 133 ? -2.267  38.842  39.110 1.00 13.66 ?  99   TYR B HE1  1 
ATOM   7051  H HE2  . TYR B 1 133 ? -3.727  37.964  42.729 1.00 13.76 ?  99   TYR B HE2  1 
ATOM   7052  H HH   . TYR B 1 133 ? -2.159  36.698  41.669 1.00 13.60 ?  99   TYR B HH   1 
ATOM   7053  N N    . ARG B 1 134 ? -1.664  42.893  41.306 1.00 10.24 ?  100  ARG B N    1 
ATOM   7054  C CA   . ARG B 1 134 ? -0.421  42.727  40.563 1.00 10.87 ?  100  ARG B CA   1 
ATOM   7055  C C    . ARG B 1 134 ? 0.351   41.543  41.099 1.00 12.28 ?  100  ARG B C    1 
ATOM   7056  O O    . ARG B 1 134 ? 0.665   41.497  42.281 1.00 12.24 ?  100  ARG B O    1 
ATOM   7057  C CB   . ARG B 1 134 ? 0.451   43.985  40.569 1.00 11.45 ?  100  ARG B CB   1 
ATOM   7058  C CG   . ARG B 1 134 ? 1.462   44.007  39.431 1.00 11.15 ?  100  ARG B CG   1 
ATOM   7059  C CD   . ARG B 1 134 ? 0.853   44.446  38.130 1.00 12.91 ?  100  ARG B CD   1 
ATOM   7060  N NE   . ARG B 1 134 ? 1.848   44.713  37.103 1.00 12.90 ?  100  ARG B NE   1 
ATOM   7061  C CZ   . ARG B 1 134 ? 1.984   44.070  35.959 1.00 12.44 ?  100  ARG B CZ   1 
ATOM   7062  N NH1  . ARG B 1 134 ? 1.241   43.028  35.640 1.00 13.99 ?  100  ARG B NH1  1 
ATOM   7063  N NH2  . ARG B 1 134 ? 2.890   44.505  35.078 1.00 14.90 ?  100  ARG B NH2  1 
ATOM   7064  H H    . ARG B 1 134 ? -1.619  42.679  42.138 1.00 12.29 ?  100  ARG B H    1 
ATOM   7065  H HA   . ARG B 1 134 ? -0.663  42.540  39.643 1.00 13.05 ?  100  ARG B HA   1 
ATOM   7066  H HB2  . ARG B 1 134 ? -0.119  44.765  40.480 1.00 13.74 ?  100  ARG B HB2  1 
ATOM   7067  H HB3  . ARG B 1 134 ? 0.940   44.026  41.406 1.00 13.74 ?  100  ARG B HB3  1 
ATOM   7068  H HG2  . ARG B 1 134 ? 2.176   44.624  39.653 1.00 13.39 ?  100  ARG B HG2  1 
ATOM   7069  H HG3  . ARG B 1 134 ? 1.821   43.114  39.309 1.00 13.39 ?  100  ARG B HG3  1 
ATOM   7070  H HD2  . ARG B 1 134 ? 0.266   43.746  37.803 1.00 15.49 ?  100  ARG B HD2  1 
ATOM   7071  H HD3  . ARG B 1 134 ? 0.347   45.261  38.276 1.00 15.49 ?  100  ARG B HD3  1 
ATOM   7072  H HE   . ARG B 1 134 ? 2.402   45.353  37.257 1.00 15.48 ?  100  ARG B HE   1 
ATOM   7073  H HH11 . ARG B 1 134 ? 0.641   42.744  36.187 1.00 16.79 ?  100  ARG B HH11 1 
ATOM   7074  H HH12 . ARG B 1 134 ? 1.356   42.633  34.885 1.00 16.79 ?  100  ARG B HH12 1 
ATOM   7075  H HH21 . ARG B 1 134 ? 3.373   45.192  35.262 1.00 17.88 ?  100  ARG B HH21 1 
ATOM   7076  H HH22 . ARG B 1 134 ? 2.991   44.097  34.328 1.00 17.88 ?  100  ARG B HH22 1 
ATOM   7077  N N    . ASN B 1 135 ? 0.672   40.604  40.217 1.00 11.50 ?  101  ASN B N    1 
ATOM   7078  C CA   . ASN B 1 135 ? 1.495   39.459  40.608 1.00 10.88 ?  101  ASN B CA   1 
ATOM   7079  C C    . ASN B 1 135 ? 2.966   39.845  40.488 1.00 11.16 ?  101  ASN B C    1 
ATOM   7080  O O    . ASN B 1 135 ? 3.391   40.333  39.429 1.00 11.80 ?  101  ASN B O    1 
ATOM   7081  C CB   . ASN B 1 135 ? 1.156   38.251  39.732 1.00 11.82 ?  101  ASN B CB   1 
ATOM   7082  C CG   . ASN B 1 135 ? 1.560   36.963  40.374 1.00 10.49 ?  101  ASN B CG   1 
ATOM   7083  O OD1  . ASN B 1 135 ? 2.745   36.717  40.572 1.00 11.37 ?  101  ASN B OD1  1 
ATOM   7084  N ND2  . ASN B 1 135 ? 0.575   36.164  40.770 1.00 11.43 ?  101  ASN B ND2  1 
ATOM   7085  H H    . ASN B 1 135 ? 0.428   40.605  39.392 1.00 13.80 ?  101  ASN B H    1 
ATOM   7086  H HA   . ASN B 1 135 ? 1.328   39.208  41.530 1.00 13.06 ?  101  ASN B HA   1 
ATOM   7087  H HB2  . ASN B 1 135 ? 0.198   38.226  39.580 1.00 14.19 ?  101  ASN B HB2  1 
ATOM   7088  H HB3  . ASN B 1 135 ? 1.625   38.328  38.887 1.00 14.19 ?  101  ASN B HB3  1 
ATOM   7089  H HD21 . ASN B 1 135 ? 0.757   35.411  41.145 1.00 13.71 ?  101  ASN B HD21 1 
ATOM   7090  H HD22 . ASN B 1 135 ? -0.243  36.399  40.652 1.00 13.71 ?  101  ASN B HD22 1 
ATOM   7091  N N    . VAL B 1 136 ? 3.739   39.618  41.562 1.00 11.14 ?  102  VAL B N    1 
ATOM   7092  C CA   . VAL B 1 136 ? 5.144   40.032  41.586 1.00 12.59 ?  102  VAL B CA   1 
ATOM   7093  C C    . VAL B 1 136 ? 6.042   39.160  40.740 1.00 13.17 ?  102  VAL B C    1 
ATOM   7094  O O    . VAL B 1 136 ? 7.109   39.616  40.343 1.00 12.83 ?  102  VAL B O    1 
ATOM   7095  C CB   . VAL B 1 136 ? 5.632   40.159  43.043 1.00 12.71 ?  102  VAL B CB   1 
ATOM   7096  C CG1  . VAL B 1 136 ? 5.903   38.794  43.691 1.00 11.81 ?  102  VAL B CG1  1 
ATOM   7097  C CG2  . VAL B 1 136 ? 6.877   41.061  43.169 1.00 13.53 ?  102  VAL B CG2  1 
ATOM   7098  H H    . VAL B 1 136 ? 3.473   39.229  42.282 1.00 13.37 ?  102  VAL B H    1 
ATOM   7099  H HA   . VAL B 1 136 ? 5.203   40.911  41.181 1.00 15.11 ?  102  VAL B HA   1 
ATOM   7100  H HB   . VAL B 1 136 ? 4.907   40.581  43.531 1.00 15.26 ?  102  VAL B HB   1 
ATOM   7101  H HG11 . VAL B 1 136 ? 6.001   38.912  44.648 1.00 14.18 ?  102  VAL B HG11 1 
ATOM   7102  H HG12 . VAL B 1 136 ? 5.156   38.202  43.505 1.00 14.18 ?  102  VAL B HG12 1 
ATOM   7103  H HG13 . VAL B 1 136 ? 6.718   38.424  43.318 1.00 14.18 ?  102  VAL B HG13 1 
ATOM   7104  H HG21 . VAL B 1 136 ? 7.078   41.191  44.109 1.00 16.24 ?  102  VAL B HG21 1 
ATOM   7105  H HG22 . VAL B 1 136 ? 7.625   40.629  42.727 1.00 16.24 ?  102  VAL B HG22 1 
ATOM   7106  H HG23 . VAL B 1 136 ? 6.692   41.915  42.748 1.00 16.24 ?  102  VAL B HG23 1 
ATOM   7107  N N    . VAL B 1 137 ? 5.657   37.921  40.421 1.00 12.76 ?  103  VAL B N    1 
ATOM   7108  C CA   . VAL B 1 137 ? 6.521   37.031  39.644 1.00 11.86 ?  103  VAL B CA   1 
ATOM   7109  C C    . VAL B 1 137 ? 5.830   36.296  38.517 1.00 12.60 ?  103  VAL B C    1 
ATOM   7110  O O    . VAL B 1 137 ? 6.530   35.849  37.585 1.00 14.46 ?  103  VAL B O    1 
ATOM   7111  C CB   . VAL B 1 137 ? 7.295   36.012  40.509 1.00 14.07 ?  103  VAL B CB   1 
ATOM   7112  C CG1  . VAL B 1 137 ? 8.445   36.639  41.223 1.00 14.69 ?  103  VAL B CG1  1 
ATOM   7113  C CG2  . VAL B 1 137 ? 6.386   35.292  41.480 1.00 13.26 ?  103  VAL B CG2  1 
ATOM   7114  H H    . VAL B 1 137 ? 4.902   37.574  40.643 1.00 15.31 ?  103  VAL B H    1 
ATOM   7115  H HA   . VAL B 1 137 ? 7.182   37.620  39.248 1.00 14.23 ?  103  VAL B HA   1 
ATOM   7116  H HB   . VAL B 1 137 ? 7.659   35.348  39.903 1.00 16.88 ?  103  VAL B HB   1 
ATOM   7117  H HG11 . VAL B 1 137 ? 8.989   35.941  41.620 1.00 17.63 ?  103  VAL B HG11 1 
ATOM   7118  H HG12 . VAL B 1 137 ? 8.973   37.147  40.586 1.00 17.63 ?  103  VAL B HG12 1 
ATOM   7119  H HG13 . VAL B 1 137 ? 8.105   37.228  41.915 1.00 17.63 ?  103  VAL B HG13 1 
ATOM   7120  H HG21 . VAL B 1 137 ? 6.914   34.674  42.009 1.00 15.92 ?  103  VAL B HG21 1 
ATOM   7121  H HG22 . VAL B 1 137 ? 5.962   35.944  42.059 1.00 15.92 ?  103  VAL B HG22 1 
ATOM   7122  H HG23 . VAL B 1 137 ? 5.711   34.806  40.980 1.00 15.92 ?  103  VAL B HG23 1 
ATOM   7123  N N    . ILE B 1 138 ? 4.525   36.093  38.486 1.00 11.73 ?  104  ILE B N    1 
ATOM   7124  C CA   . ILE B 1 138 ? 3.899   35.254  37.470 1.00 11.65 ?  104  ILE B CA   1 
ATOM   7125  C C    . ILE B 1 138 ? 3.406   36.140  36.343 1.00 11.98 ?  104  ILE B C    1 
ATOM   7126  O O    . ILE B 1 138 ? 2.615   37.073  36.581 1.00 13.69 ?  104  ILE B O    1 
ATOM   7127  C CB   . ILE B 1 138 ? 2.755   34.411  38.051 1.00 11.82 ?  104  ILE B CB   1 
ATOM   7128  C CG1  . ILE B 1 138 ? 3.250   33.520  39.178 1.00 13.03 ?  104  ILE B CG1  1 
ATOM   7129  C CG2  . ILE B 1 138 ? 2.151   33.552  36.973 1.00 12.36 ?  104  ILE B CG2  1 
ATOM   7130  C CD1  . ILE B 1 138 ? 2.176   32.888  39.976 1.00 12.70 ?  104  ILE B CD1  1 
ATOM   7131  H H    . ILE B 1 138 ? 3.971   36.433  39.049 1.00 14.08 ?  104  ILE B H    1 
ATOM   7132  H HA   . ILE B 1 138 ? 4.565   34.646  37.113 1.00 13.97 ?  104  ILE B HA   1 
ATOM   7133  H HB   . ILE B 1 138 ? 2.088   35.021  38.403 1.00 14.18 ?  104  ILE B HB   1 
ATOM   7134  H HG12 . ILE B 1 138 ? 3.788   32.809  38.797 1.00 15.64 ?  104  ILE B HG12 1 
ATOM   7135  H HG13 . ILE B 1 138 ? 3.787   34.056  39.782 1.00 15.64 ?  104  ILE B HG13 1 
ATOM   7136  H HG21 . ILE B 1 138 ? 1.498   32.957  37.373 1.00 14.84 ?  104  ILE B HG21 1 
ATOM   7137  H HG22 . ILE B 1 138 ? 1.719   34.124  36.319 1.00 14.84 ?  104  ILE B HG22 1 
ATOM   7138  H HG23 . ILE B 1 138 ? 2.854   33.036  36.549 1.00 14.84 ?  104  ILE B HG23 1 
ATOM   7139  H HD11 . ILE B 1 138 ? 2.562   32.515  40.785 1.00 15.24 ?  104  ILE B HD11 1 
ATOM   7140  H HD12 . ILE B 1 138 ? 1.515   33.560  40.205 1.00 15.24 ?  104  ILE B HD12 1 
ATOM   7141  H HD13 . ILE B 1 138 ? 1.765   32.184  39.451 1.00 15.24 ?  104  ILE B HD13 1 
ATOM   7142  N N    . ASN B 1 139 ? 3.748   35.795  35.100 1.00 12.25 ?  105  ASN B N    1 
ATOM   7143  C CA   . ASN B 1 139 ? 3.375   36.563  33.897 1.00 12.17 ?  105  ASN B CA   1 
ATOM   7144  C C    . ASN B 1 139 ? 2.061   36.034  33.322 1.00 11.72 ?  105  ASN B C    1 
ATOM   7145  O O    . ASN B 1 139 ? 2.018   35.428  32.251 1.00 13.83 ?  105  ASN B O    1 
ATOM   7146  C CB   . ASN B 1 139 ? 4.550   36.465  32.917 1.00 13.20 ?  105  ASN B CB   1 
ATOM   7147  C CG   . ASN B 1 139 ? 4.301   37.065  31.554 1.00 14.09 ?  105  ASN B CG   1 
ATOM   7148  O OD1  . ASN B 1 139 ? 4.808   36.533  30.565 1.00 14.50 ?  105  ASN B OD1  1 
ATOM   7149  N ND2  . ASN B 1 139 ? 3.609   38.195  31.466 1.00 15.05 ?  105  ASN B ND2  1 
ATOM   7150  H H    . ASN B 1 139 ? 4.213   35.096  34.915 1.00 14.70 ?  105  ASN B H    1 
ATOM   7151  H HA   . ASN B 1 139 ? 3.209   37.494  34.112 1.00 14.61 ?  105  ASN B HA   1 
ATOM   7152  H HB2  . ASN B 1 139 ? 5.310   36.928  33.303 1.00 15.84 ?  105  ASN B HB2  1 
ATOM   7153  H HB3  . ASN B 1 139 ? 4.764   35.528  32.787 1.00 15.84 ?  105  ASN B HB3  1 
ATOM   7154  H HD21 . ASN B 1 139 ? 3.459   38.548  30.696 1.00 18.06 ?  105  ASN B HD21 1 
ATOM   7155  H HD22 . ASN B 1 139 ? 3.311   38.573  32.178 1.00 18.06 ?  105  ASN B HD22 1 
ATOM   7156  N N    . TRP B 1 140 ? 0.965   36.239  34.077 1.00 12.18 ?  106  TRP B N    1 
ATOM   7157  C CA   . TRP B 1 140 ? -0.373  35.875  33.625 1.00 11.35 ?  106  TRP B CA   1 
ATOM   7158  C C    . TRP B 1 140 ? -0.810  36.720  32.423 1.00 12.22 ?  106  TRP B C    1 
ATOM   7159  O O    . TRP B 1 140 ? -0.296  37.811  32.202 1.00 13.04 ?  106  TRP B O    1 
ATOM   7160  C CB   . TRP B 1 140 ? -1.370  36.101  34.766 1.00 12.61 ?  106  TRP B CB   1 
ATOM   7161  C CG   . TRP B 1 140 ? -1.277  35.148  35.948 1.00 11.39 ?  106  TRP B CG   1 
ATOM   7162  C CD1  . TRP B 1 140 ? -0.993  35.476  37.229 1.00 12.32 ?  106  TRP B CD1  1 
ATOM   7163  C CD2  . TRP B 1 140 ? -1.547  33.732  35.936 1.00 11.12 ?  106  TRP B CD2  1 
ATOM   7164  N NE1  . TRP B 1 140 ? -1.069  34.336  38.038 1.00 12.49 ?  106  TRP B NE1  1 
ATOM   7165  C CE2  . TRP B 1 140 ? -1.416  33.264  37.265 1.00 12.10 ?  106  TRP B CE2  1 
ATOM   7166  C CE3  . TRP B 1 140 ? -1.900  32.811  34.939 1.00 12.78 ?  106  TRP B CE3  1 
ATOM   7167  C CZ2  . TRP B 1 140 ? -1.581  31.924  37.608 1.00 12.27 ?  106  TRP B CZ2  1 
ATOM   7168  C CZ3  . TRP B 1 140 ? -2.050  31.470  35.284 1.00 12.62 ?  106  TRP B CZ3  1 
ATOM   7169  C CH2  . TRP B 1 140 ? -1.900  31.044  36.608 1.00 13.58 ?  106  TRP B CH2  1 
ATOM   7170  H H    . TRP B 1 140 ? 0.979   36.591  34.861 1.00 14.61 ?  106  TRP B H    1 
ATOM   7171  H HA   . TRP B 1 140 ? -0.374  34.943  33.356 1.00 13.62 ?  106  TRP B HA   1 
ATOM   7172  H HB2  . TRP B 1 140 ? -1.235  36.997  35.112 1.00 15.13 ?  106  TRP B HB2  1 
ATOM   7173  H HB3  . TRP B 1 140 ? -2.266  36.017  34.404 1.00 15.13 ?  106  TRP B HB3  1 
ATOM   7174  H HD1  . TRP B 1 140 ? -0.780  36.330  37.528 1.00 14.78 ?  106  TRP B HD1  1 
ATOM   7175  H HE1  . TRP B 1 140 ? -0.921  34.314  38.885 1.00 14.99 ?  106  TRP B HE1  1 
ATOM   7176  H HE3  . TRP B 1 140 ? -2.032  33.091  34.062 1.00 15.34 ?  106  TRP B HE3  1 
ATOM   7177  H HZ2  . TRP B 1 140 ? -1.478  31.637  38.487 1.00 14.73 ?  106  TRP B HZ2  1 
ATOM   7178  H HZ3  . TRP B 1 140 ? -2.252  30.847  34.624 1.00 15.14 ?  106  TRP B HZ3  1 
ATOM   7179  H HH2  . TRP B 1 140 ? -2.019  30.145  36.813 1.00 16.30 ?  106  TRP B HH2  1 
ATOM   7180  N N    . GLY B 1 141 ? -1.727  36.169  31.650 1.00 13.24 ?  107  GLY B N    1 
ATOM   7181  C CA   . GLY B 1 141 ? -2.180  36.794  30.422 1.00 12.88 ?  107  GLY B CA   1 
ATOM   7182  C C    . GLY B 1 141 ? -3.067  38.000  30.643 1.00 14.75 ?  107  GLY B C    1 
ATOM   7183  O O    . GLY B 1 141 ? -3.515  38.311  31.743 1.00 15.22 ?  107  GLY B O    1 
ATOM   7184  H H    . GLY B 1 141 ? -2.112  35.418  31.816 1.00 15.88 ?  107  GLY B H    1 
ATOM   7185  H HA2  . GLY B 1 141 ? -1.407  37.080  29.909 1.00 15.46 ?  107  GLY B HA2  1 
ATOM   7186  H HA3  . GLY B 1 141 ? -2.680  36.145  29.903 1.00 15.46 ?  107  GLY B HA3  1 
ATOM   7187  N N    . ASN B 1 142 ? -3.374  38.647  29.524 1.00 14.02 ?  108  ASN B N    1 
ATOM   7188  C CA   . ASN B 1 142 ? -4.364  39.723  29.346 1.00 14.63 ?  108  ASN B CA   1 
ATOM   7189  C C    . ASN B 1 142 ? -3.926  41.102  29.798 1.00 14.61 ?  108  ASN B C    1 
ATOM   7190  O O    . ASN B 1 142 ? -4.777  42.018  29.810 1.00 15.47 ?  108  ASN B O    1 
ATOM   7191  C CB   . ASN B 1 142 ? -5.753  39.348  29.867 1.00 14.98 ?  108  ASN B CB   1 
ATOM   7192  C CG   . ASN B 1 142 ? -6.370  38.267  29.058 1.00 16.00 ?  108  ASN B CG   1 
ATOM   7193  O OD1  . ASN B 1 142 ? -6.219  38.268  27.822 1.00 18.82 ?  108  ASN B OD1  1 
ATOM   7194  N ND2  . ASN B 1 142 ? -7.027  37.359  29.708 1.00 15.97 ?  108  ASN B ND2  1 
ATOM   7195  H H    . ASN B 1 142 ? -2.986  38.466  28.778 1.00 16.82 ?  108  ASN B H    1 
ATOM   7196  H HA   . ASN B 1 142 ? -4.461  39.847  28.389 1.00 17.56 ?  108  ASN B HA   1 
ATOM   7197  H HB2  . ASN B 1 142 ? -5.678  39.038  30.783 1.00 17.98 ?  108  ASN B HB2  1 
ATOM   7198  H HB3  . ASN B 1 142 ? -6.331  40.127  29.827 1.00 17.98 ?  108  ASN B HB3  1 
ATOM   7199  H HD21 . ASN B 1 142 ? -7.402  36.712  29.282 1.00 19.16 ?  108  ASN B HD21 1 
ATOM   7200  H HD22 . ASN B 1 142 ? -7.088  37.402  30.565 1.00 19.16 ?  108  ASN B HD22 1 
ATOM   7201  N N    . TYR B 1 143 ? -2.640  41.322  30.066 1.00 13.84 ?  109  TYR B N    1 
ATOM   7202  C CA   . TYR B 1 143 ? -2.072  42.648  30.248 1.00 13.96 ?  109  TYR B CA   1 
ATOM   7203  C C    . TYR B 1 143 ? -1.453  43.059  28.920 1.00 16.69 ?  109  TYR B C    1 
ATOM   7204  O O    . TYR B 1 143 ? -0.374  42.553  28.539 1.00 16.10 ?  109  TYR B O    1 
ATOM   7205  C CB   . TYR B 1 143 ? -1.000  42.636  31.323 1.00 13.70 ?  109  TYR B CB   1 
ATOM   7206  C CG   . TYR B 1 143 ? -1.523  42.325  32.717 1.00 14.01 ?  109  TYR B CG   1 
ATOM   7207  C CD1  . TYR B 1 143 ? -2.101  43.319  33.510 1.00 12.95 ?  109  TYR B CD1  1 
ATOM   7208  C CD2  . TYR B 1 143 ? -1.437  41.049  33.246 1.00 12.68 ?  109  TYR B CD2  1 
ATOM   7209  C CE1  . TYR B 1 143 ? -2.558  43.049  34.778 1.00 12.55 ?  109  TYR B CE1  1 
ATOM   7210  C CE2  . TYR B 1 143 ? -1.880  40.764  34.509 1.00 12.99 ?  109  TYR B CE2  1 
ATOM   7211  C CZ   . TYR B 1 143 ? -2.432  41.749  35.285 1.00 11.40 ?  109  TYR B CZ   1 
ATOM   7212  O OH   . TYR B 1 143 ? -2.858  41.454  36.569 1.00 11.82 ?  109  TYR B OH   1 
ATOM   7213  H H    . TYR B 1 143 ? -2.059  40.693  30.148 1.00 16.60 ?  109  TYR B H    1 
ATOM   7214  H HA   . TYR B 1 143 ? -2.771  43.269  30.507 1.00 16.75 ?  109  TYR B HA   1 
ATOM   7215  H HB2  . TYR B 1 143 ? -0.341  41.960  31.098 1.00 16.44 ?  109  TYR B HB2  1 
ATOM   7216  H HB3  . TYR B 1 143 ? -0.581  43.510  31.354 1.00 16.44 ?  109  TYR B HB3  1 
ATOM   7217  H HD1  . TYR B 1 143 ? -2.178  44.182  33.172 1.00 15.53 ?  109  TYR B HD1  1 
ATOM   7218  H HD2  . TYR B 1 143 ? -1.069  40.368  32.730 1.00 15.22 ?  109  TYR B HD2  1 
ATOM   7219  H HE1  . TYR B 1 143 ? -2.945  43.721  35.293 1.00 15.07 ?  109  TYR B HE1  1 
ATOM   7220  H HE2  . TYR B 1 143 ? -1.805  39.899  34.843 1.00 15.59 ?  109  TYR B HE2  1 
ATOM   7221  H HH   . TYR B 1 143 ? -2.860  42.150  37.038 1.00 14.18 ?  109  TYR B HH   1 
ATOM   7222  N N    . LYS B 1 144 ? -2.084  44.010  28.236 1.00 15.56 ?  110  LYS B N    1 
ATOM   7223  C CA   . LYS B 1 144 ? -1.541  44.417  26.941 1.00 15.47 ?  110  LYS B CA   1 
ATOM   7224  C C    . LYS B 1 144 ? -0.122  44.949  27.083 1.00 15.97 ?  110  LYS B C    1 
ATOM   7225  O O    . LYS B 1 144 ? 0.728   44.710  26.203 1.00 16.54 ?  110  LYS B O    1 
ATOM   7226  C CB   . LYS B 1 144 ? -2.470  45.404  26.233 1.00 16.27 ?  110  LYS B CB   1 
ATOM   7227  C CG   . LYS B 1 144 ? -2.452  46.770  26.799 1.00 21.35 ?  110  LYS B CG   1 
ATOM   7228  C CD   . LYS B 1 144 ? -3.344  47.706  25.941 1.00 20.96 ?  110  LYS B CD   1 
ATOM   7229  C CE   . LYS B 1 144 ? -3.605  49.006  26.670 1.00 23.13 ?  110  LYS B CE   1 
ATOM   7230  N NZ   . LYS B 1 144 ? -2.401  49.849  26.852 1.00 27.10 ?  110  LYS B NZ   1 
ATOM   7231  H H    . LYS B 1 144 ? -2.798  44.419  28.487 1.00 18.67 ?  110  LYS B H    1 
ATOM   7232  H HA   . LYS B 1 144 ? -1.498  43.638  26.364 1.00 18.57 ?  110  LYS B HA   1 
ATOM   7233  H HB2  . LYS B 1 144 ? -2.202  45.468  25.302 1.00 19.52 ?  110  LYS B HB2  1 
ATOM   7234  H HB3  . LYS B 1 144 ? -3.379  45.073  26.294 1.00 19.52 ?  110  LYS B HB3  1 
ATOM   7235  H HG2  . LYS B 1 144 ? -2.798  46.754  27.705 1.00 25.62 ?  110  LYS B HG2  1 
ATOM   7236  H HG3  . LYS B 1 144 ? -1.545  47.114  26.796 1.00 25.62 ?  110  LYS B HG3  1 
ATOM   7237  H HD2  . LYS B 1 144 ? -2.895  47.906  25.105 1.00 25.16 ?  110  LYS B HD2  1 
ATOM   7238  H HD3  . LYS B 1 144 ? -4.194  47.274  25.766 1.00 25.16 ?  110  LYS B HD3  1 
ATOM   7239  H HE2  . LYS B 1 144 ? -4.252  49.522  26.164 1.00 27.76 ?  110  LYS B HE2  1 
ATOM   7240  H HE3  . LYS B 1 144 ? -3.958  48.804  27.550 1.00 27.76 ?  110  LYS B HE3  1 
ATOM   7241  H HZ1  . LYS B 1 144 ? -2.055  50.060  26.060 1.00 32.52 ?  110  LYS B HZ1  1 
ATOM   7242  H HZ2  . LYS B 1 144 ? -2.616  50.599  27.282 1.00 32.52 ?  110  LYS B HZ2  1 
ATOM   7243  H HZ3  . LYS B 1 144 ? -1.790  49.409  27.326 1.00 32.52 ?  110  LYS B HZ3  1 
ATOM   7244  N N    . ASN B 1 145 ? 0.167   45.672  28.161 1.00 14.93 ?  111  ASN B N    1 
ATOM   7245  C CA   . ASN B 1 145 ? 1.482   46.274  28.293 1.00 15.28 ?  111  ASN B CA   1 
ATOM   7246  C C    . ASN B 1 145 ? 2.526   45.220  28.624 1.00 16.43 ?  111  ASN B C    1 
ATOM   7247  O O    . ASN B 1 145 ? 3.679   45.329  28.192 1.00 16.88 ?  111  ASN B O    1 
ATOM   7248  C CB   . ASN B 1 145 ? 1.513   47.363  29.358 1.00 15.66 ?  111  ASN B CB   1 
ATOM   7249  C CG   . ASN B 1 145 ? 0.633   48.548  28.998 1.00 19.87 ?  111  ASN B CG   1 
ATOM   7250  O OD1  . ASN B 1 145 ? 0.272   48.722  27.828 1.00 19.57 ?  111  ASN B OD1  1 
ATOM   7251  N ND2  . ASN B 1 145 ? 0.237   49.342  29.993 1.00 17.61 ?  111  ASN B ND2  1 
ATOM   7252  H H    . ASN B 1 145 ? -0.371  45.824  28.815 1.00 17.91 ?  111  ASN B H    1 
ATOM   7253  H HA   . ASN B 1 145 ? 1.694   46.700  27.448 1.00 18.34 ?  111  ASN B HA   1 
ATOM   7254  H HB2  . ASN B 1 145 ? 1.195   46.995  30.197 1.00 18.79 ?  111  ASN B HB2  1 
ATOM   7255  H HB3  . ASN B 1 145 ? 2.423   47.682  29.459 1.00 18.79 ?  111  ASN B HB3  1 
ATOM   7256  H HD21 . ASN B 1 145 ? -0.262  50.023  29.827 1.00 21.13 ?  111  ASN B HD21 1 
ATOM   7257  H HD22 . ASN B 1 145 ? 0.480   49.173  30.800 1.00 21.13 ?  111  ASN B HD22 1 
ATOM   7258  N N    . ASP B 1 146 ? 2.144   44.195  29.395 1.00 14.73 ?  112  ASP B N    1 
ATOM   7259  C CA   . ASP B 1 146 ? 3.078   43.112  29.661 1.00 16.15 ?  112  ASP B CA   1 
ATOM   7260  C C    . ASP B 1 146 ? 3.369   42.337  28.389 1.00 14.80 ?  112  ASP B C    1 
ATOM   7261  O O    . ASP B 1 146 ? 4.529   41.994  28.133 1.00 17.22 ?  112  ASP B O    1 
ATOM   7262  C CB   . ASP B 1 146 ? 2.533   42.132  30.693 1.00 13.24 ?  112  ASP B CB   1 
ATOM   7263  C CG   . ASP B 1 146 ? 2.360   42.749  32.059 1.00 14.98 ?  112  ASP B CG   1 
ATOM   7264  O OD1  . ASP B 1 146 ? 2.604   43.962  32.239 1.00 14.28 ?  112  ASP B OD1  1 
ATOM   7265  O OD2  . ASP B 1 146 ? 1.928   41.997  32.961 1.00 14.04 ?  112  ASP B OD2  1 
ATOM   7266  H H    . ASP B 1 146 ? 1.371   44.110  29.763 1.00 17.67 ?  112  ASP B H    1 
ATOM   7267  H HA   . ASP B 1 146 ? 3.887   43.512  30.017 1.00 19.38 ?  112  ASP B HA   1 
ATOM   7268  H HB2  . ASP B 1 146 ? 1.666   41.813  30.397 1.00 15.88 ?  112  ASP B HB2  1 
ATOM   7269  H HB3  . ASP B 1 146 ? 3.149   41.387  30.777 1.00 15.88 ?  112  ASP B HB3  1 
ATOM   7270  N N    . ASP B 1 147 ? 2.337   42.065  27.580 1.00 14.77 ?  113  ASP B N    1 
ATOM   7271  C CA   . ASP B 1 147 ? 2.561   41.341  26.334 1.00 16.62 ?  113  ASP B CA   1 
ATOM   7272  C C    . ASP B 1 147 ? 3.540   42.101  25.433 1.00 18.13 ?  113  ASP B C    1 
ATOM   7273  O O    . ASP B 1 147 ? 4.442   41.501  24.833 1.00 18.49 ?  113  ASP B O    1 
ATOM   7274  C CB   . ASP B 1 147 ? 1.242   41.109  25.618 1.00 15.83 ?  113  ASP B CB   1 
ATOM   7275  C CG   . ASP B 1 147 ? 0.310   40.166  26.343 1.00 16.57 ?  113  ASP B CG   1 
ATOM   7276  O OD1  . ASP B 1 147 ? 0.685   39.573  27.371 1.00 17.89 ?  113  ASP B OD1  1 
ATOM   7277  O OD2  . ASP B 1 147 ? -0.842  39.980  25.851 1.00 18.79 ?  113  ASP B OD2  1 
ATOM   7278  H H    . ASP B 1 147 ? 1.519   42.284  27.730 1.00 17.73 ?  113  ASP B H    1 
ATOM   7279  H HA   . ASP B 1 147 ? 2.944   40.473  26.535 1.00 19.95 ?  113  ASP B HA   1 
ATOM   7280  H HB2  . ASP B 1 147 ? 0.786   41.959  25.522 1.00 18.99 ?  113  ASP B HB2  1 
ATOM   7281  H HB3  . ASP B 1 147 ? 1.424   40.729  24.744 1.00 18.99 ?  113  ASP B HB3  1 
ATOM   7282  N N    . GLU B 1 148 ? 3.407   43.423  25.358 1.00 17.57 ?  114  GLU B N    1 
ATOM   7283  C CA   . GLU B 1 148 ? 4.320   44.231  24.551 1.00 17.62 ?  114  GLU B CA   1 
ATOM   7284  C C    . GLU B 1 148 ? 5.736   44.169  25.106 1.00 18.83 ?  114  GLU B C    1 
ATOM   7285  O O    . GLU B 1 148 ? 6.707   44.002  24.350 1.00 21.68 ?  114  GLU B O    1 
ATOM   7286  C CB   . GLU B 1 148 ? 3.802   45.671  24.503 1.00 18.67 ?  114  GLU B CB   1 
ATOM   7287  C CG   . GLU B 1 148 ? 4.779   46.657  23.851 1.00 21.30 ?  114  GLU B CG   1 
ATOM   7288  C CD   . GLU B 1 148 ? 4.265   48.082  23.843 1.00 42.81 ?  114  GLU B CD   1 
ATOM   7289  O OE1  . GLU B 1 148 ? 3.833   48.569  24.914 1.00 30.45 ?  114  GLU B OE1  1 
ATOM   7290  O OE2  . GLU B 1 148 ? 4.272   48.703  22.752 1.00 33.08 ?  114  GLU B OE2  1 
ATOM   7291  H H    . GLU B 1 148 ? 2.800   43.877  25.764 1.00 21.09 ?  114  GLU B H    1 
ATOM   7292  H HA   . GLU B 1 148 ? 4.349   43.888  23.644 1.00 21.15 ?  114  GLU B HA   1 
ATOM   7293  H HB2  . GLU B 1 148 ? 2.978   45.689  23.991 1.00 22.40 ?  114  GLU B HB2  1 
ATOM   7294  H HB3  . GLU B 1 148 ? 3.636   45.974  25.409 1.00 22.40 ?  114  GLU B HB3  1 
ATOM   7295  H HG2  . GLU B 1 148 ? 5.615   46.644  24.343 1.00 25.56 ?  114  GLU B HG2  1 
ATOM   7296  H HG3  . GLU B 1 148 ? 4.931   46.389  22.931 1.00 25.56 ?  114  GLU B HG3  1 
ATOM   7297  N N    . PHE B 1 149 ? 5.885   44.334  26.419 1.00 17.30 ?  115  PHE B N    1 
ATOM   7298  C CA   . PHE B 1 149 ? 7.189   44.332  27.066 1.00 16.65 ?  115  PHE B CA   1 
ATOM   7299  C C    . PHE B 1 149 ? 7.881   42.989  26.895 1.00 18.05 ?  115  PHE B C    1 
ATOM   7300  O O    . PHE B 1 149 ? 9.090   42.942  26.593 1.00 20.24 ?  115  PHE B O    1 
ATOM   7301  C CB   . PHE B 1 149 ? 6.957   44.651  28.546 1.00 18.91 ?  115  PHE B CB   1 
ATOM   7302  C CG   . PHE B 1 149 ? 8.166   44.557  29.393 1.00 16.59 ?  115  PHE B CG   1 
ATOM   7303  C CD1  . PHE B 1 149 ? 9.181   45.505  29.292 1.00 18.49 ?  115  PHE B CD1  1 
ATOM   7304  C CD2  . PHE B 1 149 ? 8.292   43.541  30.310 1.00 17.23 ?  115  PHE B CD2  1 
ATOM   7305  C CE1  . PHE B 1 149 ? 10.290  45.424  30.080 1.00 18.54 ?  115  PHE B CE1  1 
ATOM   7306  C CE2  . PHE B 1 149 ? 9.412   43.450  31.089 1.00 18.41 ?  115  PHE B CE2  1 
ATOM   7307  C CZ   . PHE B 1 149 ? 10.408  44.401  30.972 1.00 18.65 ?  115  PHE B CZ   1 
ATOM   7308  H H    . PHE B 1 149 ? 5.233   44.451  26.967 1.00 20.76 ?  115  PHE B H    1 
ATOM   7309  H HA   . PHE B 1 149 ? 7.774   45.001  26.675 1.00 19.98 ?  115  PHE B HA   1 
ATOM   7310  H HB2  . PHE B 1 149 ? 6.620   45.558  28.617 1.00 22.69 ?  115  PHE B HB2  1 
ATOM   7311  H HB3  . PHE B 1 149 ? 6.305   44.026  28.898 1.00 22.69 ?  115  PHE B HB3  1 
ATOM   7312  H HD1  . PHE B 1 149 ? 9.101   46.200  28.680 1.00 22.19 ?  115  PHE B HD1  1 
ATOM   7313  H HD2  . PHE B 1 149 ? 7.613   42.913  30.401 1.00 20.68 ?  115  PHE B HD2  1 
ATOM   7314  H HE1  . PHE B 1 149 ? 10.962  46.063  30.010 1.00 22.24 ?  115  PHE B HE1  1 
ATOM   7315  H HE2  . PHE B 1 149 ? 9.503   42.751  31.695 1.00 22.09 ?  115  PHE B HE2  1 
ATOM   7316  H HZ   . PHE B 1 149 ? 11.166  44.341  31.508 1.00 22.38 ?  115  PHE B HZ   1 
ATOM   7317  N N    . ILE B 1 150 ? 7.148   41.897  27.076 1.00 18.56 ?  116  ILE B N    1 
ATOM   7318  C CA   . ILE B 1 150 ? 7.766   40.569  27.005 1.00 19.02 ?  116  ILE B CA   1 
ATOM   7319  C C    . ILE B 1 150 ? 8.111   40.207  25.567 1.00 23.54 ?  116  ILE B C    1 
ATOM   7320  O O    . ILE B 1 150 ? 9.151   39.583  25.304 1.00 22.24 ?  116  ILE B O    1 
ATOM   7321  C CB   . ILE B 1 150 ? 6.849   39.531  27.669 1.00 18.17 ?  116  ILE B CB   1 
ATOM   7322  C CG1  . ILE B 1 150 ? 6.671   39.782  29.166 1.00 18.87 ?  116  ILE B CG1  1 
ATOM   7323  C CG2  . ILE B 1 150 ? 7.339   38.080  27.434 1.00 19.59 ?  116  ILE B CG2  1 
ATOM   7324  C CD1  . ILE B 1 150 ? 7.947   39.762  29.956 1.00 17.49 ?  116  ILE B CD1  1 
ATOM   7325  H H    . ILE B 1 150 ? 6.304   41.892  27.240 1.00 22.27 ?  116  ILE B H    1 
ATOM   7326  H HA   . ILE B 1 150 ? 8.602   40.585  27.498 1.00 22.82 ?  116  ILE B HA   1 
ATOM   7327  H HB   . ILE B 1 150 ? 5.986   39.638  27.239 1.00 21.81 ?  116  ILE B HB   1 
ATOM   7328  H HG12 . ILE B 1 150 ? 6.265   40.655  29.287 1.00 22.65 ?  116  ILE B HG12 1 
ATOM   7329  H HG13 . ILE B 1 150 ? 6.091   39.094  29.528 1.00 22.65 ?  116  ILE B HG13 1 
ATOM   7330  H HG21 . ILE B 1 150 ? 6.856   37.484  28.026 1.00 23.50 ?  116  ILE B HG21 1 
ATOM   7331  H HG22 . ILE B 1 150 ? 7.172   37.836  26.510 1.00 23.50 ?  116  ILE B HG22 1 
ATOM   7332  H HG23 . ILE B 1 150 ? 8.290   38.034  27.622 1.00 23.50 ?  116  ILE B HG23 1 
ATOM   7333  H HD11 . ILE B 1 150 ? 7.734   39.830  30.900 1.00 20.99 ?  116  ILE B HD11 1 
ATOM   7334  H HD12 . ILE B 1 150 ? 8.413   38.930  29.782 1.00 20.99 ?  116  ILE B HD12 1 
ATOM   7335  H HD13 . ILE B 1 150 ? 8.498   40.513  29.686 1.00 20.99 ?  116  ILE B HD13 1 
ATOM   7336  N N    . SER B 1 151 ? 7.247   40.556  24.619 1.00 21.31 ?  117  SER B N    1 
ATOM   7337  C CA   . SER B 1 151 ? 7.600   40.362  23.210 1.00 24.60 ?  117  SER B CA   1 
ATOM   7338  C C    . SER B 1 151 ? 8.895   41.096  22.866 1.00 25.30 ?  117  SER B C    1 
ATOM   7339  O O    . SER B 1 151 ? 9.790   40.517  22.239 1.00 28.59 ?  117  SER B O    1 
ATOM   7340  C CB   . SER B 1 151 ? 6.455   40.800  22.300 1.00 27.13 ?  117  SER B CB   1 
ATOM   7341  O OG   . SER B 1 151 ? 5.436   39.816  22.295 1.00 36.76 ?  117  SER B OG   1 
ATOM   7342  H H    . SER B 1 151 ? 6.470   40.898  24.756 1.00 25.57 ?  117  SER B H    1 
ATOM   7343  H HA   . SER B 1 151 ? 7.742   39.415  23.054 1.00 29.53 ?  117  SER B HA   1 
ATOM   7344  H HB2  . SER B 1 151 ? 6.089   41.637  22.627 1.00 32.56 ?  117  SER B HB2  1 
ATOM   7345  H HB3  . SER B 1 151 ? 6.791   40.916  21.397 1.00 32.56 ?  117  SER B HB3  1 
ATOM   7346  H HG   . SER B 1 151 ? 5.201   39.642  23.082 1.00 44.12 ?  117  SER B HG   1 
ATOM   7347  N N    . LYS B 1 152 ? 9.024   42.365  23.274 1.00 21.78 ?  118  LYS B N    1 
ATOM   7348  C CA   . LYS B 1 152 ? 10.228  43.127  22.957 1.00 22.96 ?  118  LYS B CA   1 
ATOM   7349  C C    . LYS B 1 152 ? 11.434  42.614  23.716 1.00 31.90 ?  118  LYS B C    1 
ATOM   7350  O O    . LYS B 1 152 ? 12.566  42.731  23.227 1.00 25.35 ?  118  LYS B O    1 
ATOM   7351  C CB   . LYS B 1 152 ? 10.061  44.618  23.257 1.00 27.36 ?  118  LYS B CB   1 
ATOM   7352  C CG   . LYS B 1 152 ? 9.091   45.324  22.330 1.00 50.21 ?  118  LYS B CG   1 
ATOM   7353  C CD   . LYS B 1 152 ? 8.910   46.798  22.670 1.00 51.84 ?  118  LYS B CD   1 
ATOM   7354  C CE   . LYS B 1 152 ? 8.021   47.514  21.646 1.00 57.16 ?  118  LYS B CE   1 
ATOM   7355  N NZ   . LYS B 1 152 ? 7.306   46.561  20.730 1.00 33.79 ?  118  LYS B NZ   1 
ATOM   7356  H H    . LYS B 1 152 ? 8.436   42.798  23.728 1.00 26.13 ?  118  LYS B H    1 
ATOM   7357  H HA   . LYS B 1 152 ? 10.374  43.029  22.003 1.00 27.56 ?  118  LYS B HA   1 
ATOM   7358  H HB2  . LYS B 1 152 ? 9.731   44.718  24.164 1.00 32.83 ?  118  LYS B HB2  1 
ATOM   7359  H HB3  . LYS B 1 152 ? 10.924  45.051  23.169 1.00 32.83 ?  118  LYS B HB3  1 
ATOM   7360  H HG2  . LYS B 1 152 ? 9.424   45.266  21.421 1.00 60.26 ?  118  LYS B HG2  1 
ATOM   7361  H HG3  . LYS B 1 152 ? 8.224   44.894  22.393 1.00 60.26 ?  118  LYS B HG3  1 
ATOM   7362  H HD2  . LYS B 1 152 ? 8.493   46.877  23.542 1.00 62.20 ?  118  LYS B HD2  1 
ATOM   7363  H HD3  . LYS B 1 152 ? 9.777   47.234  22.676 1.00 62.20 ?  118  LYS B HD3  1 
ATOM   7364  H HE2  . LYS B 1 152 ? 7.353   48.035  22.117 1.00 68.59 ?  118  LYS B HE2  1 
ATOM   7365  H HE3  . LYS B 1 152 ? 8.573   48.097  21.101 1.00 68.59 ?  118  LYS B HE3  1 
ATOM   7366  H HZ1  . LYS B 1 152 ? 6.755   47.009  20.194 1.00 40.55 ?  118  LYS B HZ1  1 
ATOM   7367  H HZ2  . LYS B 1 152 ? 7.896   46.117  20.232 1.00 40.55 ?  118  LYS B HZ2  1 
ATOM   7368  H HZ3  . LYS B 1 152 ? 6.834   45.977  21.207 1.00 40.55 ?  118  LYS B HZ3  1 
ATOM   7369  N N    . ASN B 1 153 ? 11.221  42.057  24.908 1.00 23.51 ?  119  ASN B N    1 
ATOM   7370  C CA   . ASN B 1 153 ? 12.307  41.702  25.815 1.00 21.45 ?  119  ASN B CA   1 
ATOM   7371  C C    . ASN B 1 153 ? 12.108  40.285  26.302 1.00 23.73 ?  119  ASN B C    1 
ATOM   7372  O O    . ASN B 1 153 ? 11.788  40.067  27.470 1.00 21.00 ?  119  ASN B O    1 
ATOM   7373  C CB   . ASN B 1 153 ? 12.353  42.667  27.001 1.00 22.93 ?  119  ASN B CB   1 
ATOM   7374  C CG   . ASN B 1 153 ? 12.516  44.114  26.585 1.00 27.06 ?  119  ASN B CG   1 
ATOM   7375  O OD1  . ASN B 1 153 ? 13.613  44.532  26.198 1.00 29.17 ?  119  ASN B OD1  1 
ATOM   7376  N ND2  . ASN B 1 153 ? 11.438  44.894  26.660 1.00 22.44 ?  119  ASN B ND2  1 
ATOM   7377  H H    . ASN B 1 153 ? 10.440  41.872  25.217 1.00 28.21 ?  119  ASN B H    1 
ATOM   7378  H HA   . ASN B 1 153 ? 13.147  41.747  25.332 1.00 25.74 ?  119  ASN B HA   1 
ATOM   7379  H HB2  . ASN B 1 153 ? 11.525  42.591  27.500 1.00 27.51 ?  119  ASN B HB2  1 
ATOM   7380  H HB3  . ASN B 1 153 ? 13.104  42.433  27.568 1.00 27.51 ?  119  ASN B HB3  1 
ATOM   7381  H HD21 . ASN B 1 153 ? 11.490  45.722  26.433 1.00 26.93 ?  119  ASN B HD21 1 
ATOM   7382  H HD22 . ASN B 1 153 ? 10.691  44.569  26.936 1.00 26.93 ?  119  ASN B HD22 1 
ATOM   7383  N N    . PRO B 1 154 ? 12.321  39.282  25.437 1.00 21.28 ?  120  PRO B N    1 
ATOM   7384  C CA   . PRO B 1 154 ? 12.182  37.887  25.880 1.00 22.49 ?  120  PRO B CA   1 
ATOM   7385  C C    . PRO B 1 154 ? 13.098  37.542  27.032 1.00 19.02 ?  120  PRO B C    1 
ATOM   7386  O O    . PRO B 1 154 ? 12.787  36.633  27.812 1.00 19.89 ?  120  PRO B O    1 
ATOM   7387  C CB   . PRO B 1 154 ? 12.516  37.066  24.622 1.00 22.90 ?  120  PRO B CB   1 
ATOM   7388  C CG   . PRO B 1 154 ? 12.919  38.052  23.579 1.00 25.12 ?  120  PRO B CG   1 
ATOM   7389  C CD   . PRO B 1 154 ? 12.773  39.429  24.042 1.00 25.49 ?  120  PRO B CD   1 
ATOM   7390  H HA   . PRO B 1 154 ? 11.262  37.705  26.129 1.00 26.99 ?  120  PRO B HA   1 
ATOM   7391  H HB2  . PRO B 1 154 ? 13.244  36.455  24.816 1.00 27.48 ?  120  PRO B HB2  1 
ATOM   7392  H HB3  . PRO B 1 154 ? 11.733  36.569  24.340 1.00 27.48 ?  120  PRO B HB3  1 
ATOM   7393  H HG2  . PRO B 1 154 ? 13.848  37.887  23.351 1.00 30.14 ?  120  PRO B HG2  1 
ATOM   7394  H HG3  . PRO B 1 154 ? 12.357  37.914  22.801 1.00 30.14 ?  120  PRO B HG3  1 
ATOM   7395  H HD2  . PRO B 1 154 ? 13.622  39.896  24.004 1.00 30.59 ?  120  PRO B HD2  1 
ATOM   7396  H HD3  . PRO B 1 154 ? 12.110  39.900  23.514 1.00 30.59 ?  120  PRO B HD3  1 
ATOM   7397  N N    . SER B 1 155 ? 14.219  38.268  27.189 1.00 19.34 ?  121  SER B N    1 
ATOM   7398  C CA   . SER B 1 155 ? 15.109  38.066  28.314 1.00 17.24 ?  121  SER B CA   1 
ATOM   7399  C C    . SER B 1 155 ? 14.503  38.492  29.645 1.00 17.28 ?  121  SER B C    1 
ATOM   7400  O O    . SER B 1 155 ? 15.083  38.200  30.686 1.00 17.98 ?  121  SER B O    1 
ATOM   7401  C CB   . SER B 1 155 ? 16.424  38.797  28.062 1.00 20.66 ?  121  SER B CB   1 
ATOM   7402  O OG   . SER B 1 155 ? 16.261  40.194  28.191 1.00 26.04 ?  121  SER B OG   1 
ATOM   7403  H H    . SER B 1 155 ? 14.477  38.884  26.647 1.00 23.21 ?  121  SER B H    1 
ATOM   7404  H HA   . SER B 1 155 ? 15.309  37.120  28.392 1.00 20.69 ?  121  SER B HA   1 
ATOM   7405  H HB2  . SER B 1 155 ? 17.081  38.496  28.709 1.00 24.79 ?  121  SER B HB2  1 
ATOM   7406  H HB3  . SER B 1 155 ? 16.729  38.597  27.163 1.00 24.79 ?  121  SER B HB3  1 
ATOM   7407  H HG   . SER B 1 155 ? 17.011  40.571  28.209 1.00 31.25 ?  121  SER B HG   1 
ATOM   7408  N N    . ALA B 1 156 ? 13.324  39.120  29.622 1.00 16.69 ?  122  ALA B N    1 
ATOM   7409  C CA   . ALA B 1 156 ? 12.637  39.469  30.872 1.00 16.78 ?  122  ALA B CA   1 
ATOM   7410  C C    . ALA B 1 156 ? 12.063  38.268  31.598 1.00 16.56 ?  122  ALA B C    1 
ATOM   7411  O O    . ALA B 1 156 ? 11.719  38.387  32.786 1.00 16.74 ?  122  ALA B O    1 
ATOM   7412  C CB   . ALA B 1 156 ? 11.516  40.466  30.608 1.00 17.40 ?  122  ALA B CB   1 
ATOM   7413  H H    . ALA B 1 156 ? 12.905  39.352  28.908 1.00 20.03 ?  122  ALA B H    1 
ATOM   7414  H HA   . ALA B 1 156 ? 13.293  39.886  31.452 1.00 20.14 ?  122  ALA B HA   1 
ATOM   7415  H HB1  . ALA B 1 156 ? 11.081  40.682  31.447 1.00 20.88 ?  122  ALA B HB1  1 
ATOM   7416  H HB2  . ALA B 1 156 ? 11.894  41.269  30.215 1.00 20.88 ?  122  ALA B HB2  1 
ATOM   7417  H HB3  . ALA B 1 156 ? 10.877  40.068  29.997 1.00 20.88 ?  122  ALA B HB3  1 
ATOM   7418  N N    . LEU B 1 157 ? 11.945  37.120  30.929 1.00 16.88 ?  123  LEU B N    1 
ATOM   7419  C CA   . LEU B 1 157 ? 11.332  35.933  31.512 1.00 16.21 ?  123  LEU B CA   1 
ATOM   7420  C C    . LEU B 1 157 ? 12.372  35.036  32.157 1.00 16.01 ?  123  LEU B C    1 
ATOM   7421  O O    . LEU B 1 157 ? 13.514  34.917  31.675 1.00 18.20 ?  123  LEU B O    1 
ATOM   7422  C CB   . LEU B 1 157 ? 10.552  35.150  30.469 1.00 15.69 ?  123  LEU B CB   1 
ATOM   7423  C CG   . LEU B 1 157 ? 9.321   35.850  29.915 1.00 16.66 ?  123  LEU B CG   1 
ATOM   7424  C CD1  . LEU B 1 157 ? 8.622   34.941  28.895 1.00 19.33 ?  123  LEU B CD1  1 
ATOM   7425  C CD2  . LEU B 1 157 ? 8.379   36.272  31.054 1.00 19.19 ?  123  LEU B CD2  1 
ATOM   7426  H H    . LEU B 1 157 ? 12.218  37.005  30.122 1.00 20.26 ?  123  LEU B H    1 
ATOM   7427  H HA   . LEU B 1 157 ? 10.713  36.216  32.202 1.00 19.46 ?  123  LEU B HA   1 
ATOM   7428  H HB2  . LEU B 1 157 ? 11.141  34.965  29.722 1.00 18.82 ?  123  LEU B HB2  1 
ATOM   7429  H HB3  . LEU B 1 157 ? 10.255  34.318  30.872 1.00 18.82 ?  123  LEU B HB3  1 
ATOM   7430  H HG   . LEU B 1 157 ? 9.581   36.662  29.453 1.00 19.99 ?  123  LEU B HG   1 
ATOM   7431  H HD11 . LEU B 1 157 ? 7.843   35.400  28.544 1.00 23.19 ?  123  LEU B HD11 1 
ATOM   7432  H HD12 . LEU B 1 157 ? 9.240   34.741  28.175 1.00 23.19 ?  123  LEU B HD12 1 
ATOM   7433  H HD13 . LEU B 1 157 ? 8.351   34.121  29.337 1.00 23.19 ?  123  LEU B HD13 1 
ATOM   7434  H HD21 . LEU B 1 157 ? 7.543   36.583  30.673 1.00 23.03 ?  123  LEU B HD21 1 
ATOM   7435  H HD22 . LEU B 1 157 ? 8.217   35.508  31.629 1.00 23.03 ?  123  LEU B HD22 1 
ATOM   7436  H HD23 . LEU B 1 157 ? 8.797   36.985  31.561 1.00 23.03 ?  123  LEU B HD23 1 
ATOM   7437  N N    . LEU B 1 158 ? 11.977  34.386  33.241 1.00 14.86 ?  124  LEU B N    1 
ATOM   7438  C CA   . LEU B 1 158 ? 12.879  33.568  34.024 1.00 13.37 ?  124  LEU B CA   1 
ATOM   7439  C C    . LEU B 1 158 ? 13.236  32.257  33.325 1.00 15.68 ?  124  LEU B C    1 
ATOM   7440  O O    . LEU B 1 158 ? 12.361  31.496  32.884 1.00 16.06 ?  124  LEU B O    1 
ATOM   7441  C CB   . LEU B 1 158 ? 12.218  33.242  35.366 1.00 14.65 ?  124  LEU B CB   1 
ATOM   7442  C CG   . LEU B 1 158 ? 12.993  32.467  36.396 1.00 15.26 ?  124  LEU B CG   1 
ATOM   7443  C CD1  . LEU B 1 158 ? 14.262  33.274  36.809 1.00 17.19 ?  124  LEU B CD1  1 
ATOM   7444  C CD2  . LEU B 1 158 ? 12.160  32.150  37.579 1.00 14.15 ?  124  LEU B CD2  1 
ATOM   7445  H H    . LEU B 1 158 ? 11.175  34.404  33.550 1.00 17.83 ?  124  LEU B H    1 
ATOM   7446  H HA   . LEU B 1 158 ? 13.703  34.065  34.152 1.00 16.05 ?  124  LEU B HA   1 
ATOM   7447  H HB2  . LEU B 1 158 ? 11.975  34.084  35.782 1.00 17.58 ?  124  LEU B HB2  1 
ATOM   7448  H HB3  . LEU B 1 158 ? 11.420  32.723  35.177 1.00 17.58 ?  124  LEU B HB3  1 
ATOM   7449  H HG   . LEU B 1 158 ? 13.270  31.620  36.013 1.00 18.31 ?  124  LEU B HG   1 
ATOM   7450  H HD11 . LEU B 1 158 ? 14.765  32.759  37.459 1.00 20.63 ?  124  LEU B HD11 1 
ATOM   7451  H HD12 . LEU B 1 158 ? 14.805  33.433  36.021 1.00 20.63 ?  124  LEU B HD12 1 
ATOM   7452  H HD13 . LEU B 1 158 ? 13.986  34.119  37.197 1.00 20.63 ?  124  LEU B HD13 1 
ATOM   7453  H HD21 . LEU B 1 158 ? 12.670  31.587  38.183 1.00 16.98 ?  124  LEU B HD21 1 
ATOM   7454  H HD22 . LEU B 1 158 ? 11.917  32.977  38.025 1.00 16.98 ?  124  LEU B HD22 1 
ATOM   7455  H HD23 . LEU B 1 158 ? 11.361  31.684  37.288 1.00 16.98 ?  124  LEU B HD23 1 
ATOM   7456  N N    . LYS B 1 159 ? 14.548  31.967  33.266 1.00 14.55 ?  125  LYS B N    1 
ATOM   7457  C CA   . LYS B 1 159 ? 15.074  30.754  32.654 1.00 14.01 ?  125  LYS B CA   1 
ATOM   7458  C C    . LYS B 1 159 ? 15.951  30.038  33.651 1.00 15.33 ?  125  LYS B C    1 
ATOM   7459  O O    . LYS B 1 159 ? 16.553  30.639  34.548 1.00 17.25 ?  125  LYS B O    1 
ATOM   7460  C CB   . LYS B 1 159 ? 15.823  31.090  31.363 1.00 15.79 ?  125  LYS B CB   1 
ATOM   7461  C CG   . LYS B 1 159 ? 14.905  31.683  30.303 1.00 20.36 ?  125  LYS B CG   1 
ATOM   7462  C CD   . LYS B 1 159 ? 15.652  32.141  29.047 1.00 22.87 ?  125  LYS B CD   1 
ATOM   7463  C CE   . LYS B 1 159 ? 14.710  32.879  28.114 1.00 27.55 ?  125  LYS B CE   1 
ATOM   7464  N NZ   . LYS B 1 159 ? 15.444  33.379  26.918 1.00 36.93 ?  125  LYS B NZ   1 
ATOM   7465  H H    . LYS B 1 159 ? 15.162  32.478  33.585 1.00 17.46 ?  125  LYS B H    1 
ATOM   7466  H HA   . LYS B 1 159 ? 14.360  30.139  32.423 1.00 16.81 ?  125  LYS B HA   1 
ATOM   7467  H HB2  . LYS B 1 159 ? 16.518  31.738  31.559 1.00 18.95 ?  125  LYS B HB2  1 
ATOM   7468  H HB3  . LYS B 1 159 ? 16.217  30.279  31.004 1.00 18.95 ?  125  LYS B HB3  1 
ATOM   7469  H HG2  . LYS B 1 159 ? 14.257  31.012  30.036 1.00 24.43 ?  125  LYS B HG2  1 
ATOM   7470  H HG3  . LYS B 1 159 ? 14.449  32.453  30.676 1.00 24.43 ?  125  LYS B HG3  1 
ATOM   7471  H HD2  . LYS B 1 159 ? 16.373  32.741  29.297 1.00 27.44 ?  125  LYS B HD2  1 
ATOM   7472  H HD3  . LYS B 1 159 ? 16.010  31.370  28.580 1.00 27.44 ?  125  LYS B HD3  1 
ATOM   7473  H HE2  . LYS B 1 159 ? 14.009  32.277  27.818 1.00 33.06 ?  125  LYS B HE2  1 
ATOM   7474  H HE3  . LYS B 1 159 ? 14.321  33.637  28.578 1.00 33.06 ?  125  LYS B HE3  1 
ATOM   7475  H HZ1  . LYS B 1 159 ? 16.069  33.962  27.166 1.00 44.32 ?  125  LYS B HZ1  1 
ATOM   7476  H HZ2  . LYS B 1 159 ? 15.833  32.700  26.494 1.00 44.32 ?  125  LYS B HZ2  1 
ATOM   7477  H HZ3  . LYS B 1 159 ? 14.878  33.781  26.360 1.00 44.32 ?  125  LYS B HZ3  1 
ATOM   7478  N N    . ASN B 1 160 ? 16.075  28.730  33.427 1.00 16.64 ?  126  ASN B N    1 
ATOM   7479  C CA   . ASN B 1 160 ? 16.952  27.886  34.206 1.00 16.78 ?  126  ASN B CA   1 
ATOM   7480  C C    . ASN B 1 160 ? 18.388  27.972  33.648 1.00 13.75 ?  126  ASN B C    1 
ATOM   7481  O O    . ASN B 1 160 ? 18.691  28.745  32.731 1.00 15.22 ?  126  ASN B O    1 
ATOM   7482  C CB   . ASN B 1 160 ? 16.413  26.458  34.299 1.00 16.29 ?  126  ASN B CB   1 
ATOM   7483  C CG   . ASN B 1 160 ? 16.479  25.727  33.002 1.00 16.26 ?  126  ASN B CG   1 
ATOM   7484  O OD1  . ASN B 1 160 ? 17.121  26.150  32.036 1.00 17.48 ?  126  ASN B OD1  1 
ATOM   7485  N ND2  . ASN B 1 160 ? 15.785  24.610  32.950 1.00 21.36 ?  126  ASN B ND2  1 
ATOM   7486  H H    . ASN B 1 160 ? 15.648  28.306  32.813 1.00 19.97 ?  126  ASN B H    1 
ATOM   7487  H HA   . ASN B 1 160 ? 16.979  28.210  35.120 1.00 20.13 ?  126  ASN B HA   1 
ATOM   7488  H HB2  . ASN B 1 160 ? 16.938  25.964  34.948 1.00 19.55 ?  126  ASN B HB2  1 
ATOM   7489  H HB3  . ASN B 1 160 ? 15.484  26.489  34.578 1.00 19.55 ?  126  ASN B HB3  1 
ATOM   7490  H HD21 . ASN B 1 160 ? 15.781  24.139  32.230 1.00 25.63 ?  126  ASN B HD21 1 
ATOM   7491  H HD22 . ASN B 1 160 ? 15.337  24.350  33.636 1.00 25.63 ?  126  ASN B HD22 1 
ATOM   7492  N N    . GLN B 1 161 ? 19.260  27.158  34.244 1.00 18.99 ?  127  GLN B N    1 
ATOM   7493  C CA   . GLN B 1 161 ? 20.677  27.213  33.904 1.00 18.48 ?  127  GLN B CA   1 
ATOM   7494  C C    . GLN B 1 161 ? 20.970  26.734  32.487 1.00 20.99 ?  127  GLN B C    1 
ATOM   7495  O O    . GLN B 1 161 ? 22.058  27.027  31.979 1.00 20.67 ?  127  GLN B O    1 
ATOM   7496  C CB   . GLN B 1 161 ? 21.445  26.363  34.912 1.00 24.64 ?  127  GLN B CB   1 
ATOM   7497  C CG   . GLN B 1 161 ? 21.275  26.844  36.351 1.00 47.34 ?  127  GLN B CG   1 
ATOM   7498  C CD   . GLN B 1 161 ? 20.184  26.113  37.143 1.00 50.72 ?  127  GLN B CD   1 
ATOM   7499  O OE1  . GLN B 1 161 ? 19.015  25.972  36.708 1.00 32.11 ?  127  GLN B OE1  1 
ATOM   7500  N NE2  . GLN B 1 161 ? 20.562  25.670  38.343 1.00 37.26 ?  127  GLN B NE2  1 
ATOM   7501  H H    . GLN B 1 161 ? 19.057  26.573  34.841 1.00 22.79 ?  127  GLN B H    1 
ATOM   7502  H HA   . GLN B 1 161 ? 20.984  28.132  33.957 1.00 22.17 ?  127  GLN B HA   1 
ATOM   7503  H HB2  . GLN B 1 161 ? 21.123  25.449  34.863 1.00 29.57 ?  127  GLN B HB2  1 
ATOM   7504  H HB3  . GLN B 1 161 ? 22.390  26.395  34.695 1.00 29.57 ?  127  GLN B HB3  1 
ATOM   7505  H HG2  . GLN B 1 161 ? 22.114  26.715  36.821 1.00 56.80 ?  127  GLN B HG2  1 
ATOM   7506  H HG3  . GLN B 1 161 ? 21.045  27.786  36.337 1.00 56.80 ?  127  GLN B HG3  1 
ATOM   7507  H HE21 . GLN B 1 161 ? 21.366  25.804  38.617 1.00 44.72 ?  127  GLN B HE21 1 
ATOM   7508  H HE22 . GLN B 1 161 ? 20.002  25.250  38.842 1.00 44.72 ?  127  GLN B HE22 1 
ATOM   7509  N N    . ASN B 1 162 ? 20.041  26.020  31.849 1.00 18.19 ?  128  ASN B N    1 
ATOM   7510  C CA   . ASN B 1 162 ? 20.129  25.604  30.444 1.00 17.64 ?  128  ASN B CA   1 
ATOM   7511  C C    . ASN B 1 162 ? 19.463  26.613  29.514 1.00 19.08 ?  128  ASN B C    1 
ATOM   7512  O O    . ASN B 1 162 ? 19.300  26.334  28.324 1.00 19.09 ?  128  ASN B O    1 
ATOM   7513  C CB   . ASN B 1 162 ? 19.511  24.215  30.233 1.00 23.28 ?  128  ASN B CB   1 
ATOM   7514  C CG   . ASN B 1 162 ? 20.303  23.084  30.851 1.00 34.42 ?  128  ASN B CG   1 
ATOM   7515  O OD1  . ASN B 1 162 ? 21.472  23.211  31.241 1.00 25.61 ?  128  ASN B OD1  1 
ATOM   7516  N ND2  . ASN B 1 162 ? 19.656  21.927  30.925 1.00 48.33 ?  128  ASN B ND2  1 
ATOM   7517  H H    . ASN B 1 162 ? 19.316  25.751  32.225 1.00 21.83 ?  128  ASN B H    1 
ATOM   7518  H HA   . ASN B 1 162 ? 21.066  25.529  30.206 1.00 21.16 ?  128  ASN B HA   1 
ATOM   7519  H HB2  . ASN B 1 162 ? 18.626  24.206  30.630 1.00 27.93 ?  128  ASN B HB2  1 
ATOM   7520  H HB3  . ASN B 1 162 ? 19.448  24.044  29.280 1.00 27.93 ?  128  ASN B HB3  1 
ATOM   7521  H HD21 . ASN B 1 162 ? 18.849  21.866  30.633 1.00 58.00 ?  128  ASN B HD21 1 
ATOM   7522  H HD22 . ASN B 1 162 ? 20.043  21.238  31.265 1.00 58.00 ?  128  ASN B HD22 1 
ATOM   7523  N N    . ASN B 1 163 ? 19.071  27.773  30.032 1.00 17.31 ?  129  ASN B N    1 
ATOM   7524  C CA   . ASN B 1 163 ? 18.412  28.816  29.275 1.00 17.56 ?  129  ASN B CA   1 
ATOM   7525  C C    . ASN B 1 163 ? 17.025  28.400  28.765 1.00 16.43 ?  129  ASN B C    1 
ATOM   7526  O O    . ASN B 1 163 ? 16.546  28.940  27.777 1.00 18.56 ?  129  ASN B O    1 
ATOM   7527  C CB   . ASN B 1 163 ? 19.278  29.360  28.149 1.00 19.64 ?  129  ASN B CB   1 
ATOM   7528  C CG   . ASN B 1 163 ? 19.137  30.832  27.988 1.00 23.86 ?  129  ASN B CG   1 
ATOM   7529  O OD1  . ASN B 1 163 ? 19.121  31.574  28.978 1.00 27.02 ?  129  ASN B OD1  1 
ATOM   7530  N ND2  . ASN B 1 163 ? 19.010  31.285  26.752 1.00 23.26 ?  129  ASN B ND2  1 
ATOM   7531  H H    . ASN B 1 163 ? 19.185  27.983  30.859 1.00 20.78 ?  129  ASN B H    1 
ATOM   7532  H HA   . ASN B 1 163 ? 18.264  29.555  29.885 1.00 21.07 ?  129  ASN B HA   1 
ATOM   7533  H HB2  . ASN B 1 163 ? 20.209  29.166  28.342 1.00 23.56 ?  129  ASN B HB2  1 
ATOM   7534  H HB3  . ASN B 1 163 ? 19.017  28.939  27.315 1.00 23.56 ?  129  ASN B HB3  1 
ATOM   7535  H HD21 . ASN B 1 163 ? 18.926  32.129  26.610 1.00 27.91 ?  129  ASN B HD21 1 
ATOM   7536  H HD22 . ASN B 1 163 ? 19.013  30.736  26.090 1.00 27.91 ?  129  ASN B HD22 1 
ATOM   7537  N N    . GLU B 1 164 ? 16.393  27.494  29.480 1.00 15.80 ?  130  GLU B N    1 
ATOM   7538  C CA   . GLU B 1 164 ? 15.019  27.114  29.185 1.00 16.60 ?  130  GLU B CA   1 
ATOM   7539  C C    . GLU B 1 164 ? 14.052  27.893  30.080 1.00 15.61 ?  130  GLU B C    1 
ATOM   7540  O O    . GLU B 1 164 ? 14.294  28.040  31.281 1.00 16.29 ?  130  GLU B O    1 
ATOM   7541  C CB   . GLU B 1 164 ? 14.797  25.622  29.443 1.00 17.96 ?  130  GLU B CB   1 
ATOM   7542  C CG   . GLU B 1 164 ? 15.624  24.674  28.603 1.00 17.99 ?  130  GLU B CG   1 
ATOM   7543  C CD   . GLU B 1 164 ? 14.991  24.385  27.278 1.00 35.99 ?  130  GLU B CD   1 
ATOM   7544  O OE1  . GLU B 1 164 ? 15.396  25.043  26.293 1.00 31.93 ?  130  GLU B OE1  1 
ATOM   7545  O OE2  . GLU B 1 164 ? 14.109  23.493  27.211 1.00 48.71 ?  130  GLU B OE2  1 
ATOM   7546  H H    . GLU B 1 164 ? 16.738  27.078  30.150 1.00 18.96 ?  130  GLU B H    1 
ATOM   7547  H HA   . GLU B 1 164 ? 14.835  27.315  28.254 1.00 19.92 ?  130  GLU B HA   1 
ATOM   7548  H HB2  . GLU B 1 164 ? 15.009  25.440  30.372 1.00 21.56 ?  130  GLU B HB2  1 
ATOM   7549  H HB3  . GLU B 1 164 ? 13.865  25.419  29.270 1.00 21.56 ?  130  GLU B HB3  1 
ATOM   7550  H HG2  . GLU B 1 164 ? 16.495  25.070  28.441 1.00 21.59 ?  130  GLU B HG2  1 
ATOM   7551  H HG3  . GLU B 1 164 ? 15.725  23.834  29.078 1.00 21.59 ?  130  GLU B HG3  1 
ATOM   7552  N N    . LEU B 1 165 ? 12.948  28.336  29.483 1.00 15.21 ?  131  LEU B N    1 
ATOM   7553  C CA   . LEU B 1 165 ? 11.877  28.930  30.287 1.00 15.97 ?  131  LEU B CA   1 
ATOM   7554  C C    . LEU B 1 165 ? 11.375  27.914  31.300 1.00 16.20 ?  131  LEU B C    1 
ATOM   7555  O O    . LEU B 1 165 ? 11.294  26.708  31.033 1.00 16.25 ?  131  LEU B O    1 
ATOM   7556  C CB   . LEU B 1 165 ? 10.722  29.317  29.392 1.00 18.05 ?  131  LEU B CB   1 
ATOM   7557  C CG   . LEU B 1 165 ? 10.986  30.541  28.545 1.00 18.19 ?  131  LEU B CG   1 
ATOM   7558  C CD1  . LEU B 1 165 ? 9.887   30.687  27.502 1.00 20.26 ?  131  LEU B CD1  1 
ATOM   7559  C CD2  . LEU B 1 165 ? 11.070  31.811  29.392 1.00 18.13 ?  131  LEU B CD2  1 
ATOM   7560  H H    . LEU B 1 165 ? 12.796  28.306  28.637 1.00 18.25 ?  131  LEU B H    1 
ATOM   7561  H HA   . LEU B 1 165 ? 12.208  29.717  30.747 1.00 19.17 ?  131  LEU B HA   1 
ATOM   7562  H HB2  . LEU B 1 165 ? 10.532  28.578  28.793 1.00 21.66 ?  131  LEU B HB2  1 
ATOM   7563  H HB3  . LEU B 1 165 ? 9.947   29.501  29.946 1.00 21.66 ?  131  LEU B HB3  1 
ATOM   7564  H HG   . LEU B 1 165 ? 11.843  30.432  28.104 1.00 21.83 ?  131  LEU B HG   1 
ATOM   7565  H HD11 . LEU B 1 165 ? 10.069  31.471  26.960 1.00 24.31 ?  131  LEU B HD11 1 
ATOM   7566  H HD12 . LEU B 1 165 ? 9.875   29.894  26.943 1.00 24.31 ?  131  LEU B HD12 1 
ATOM   7567  H HD13 . LEU B 1 165 ? 9.035   30.787  27.953 1.00 24.31 ?  131  LEU B HD13 1 
ATOM   7568  H HD21 . LEU B 1 165 ? 11.104  32.581  28.804 1.00 21.75 ?  131  LEU B HD21 1 
ATOM   7569  H HD22 . LEU B 1 165 ? 10.287  31.864  29.962 1.00 21.75 ?  131  LEU B HD22 1 
ATOM   7570  H HD23 . LEU B 1 165 ? 11.873  31.775  29.936 1.00 21.75 ?  131  LEU B HD23 1 
ATOM   7571  N N    . VAL B 1 166 ? 10.998  28.403  32.474 1.00 14.81 ?  132  VAL B N    1 
ATOM   7572  C CA   . VAL B 1 166 ? 10.327  27.625  33.496 1.00 14.32 ?  132  VAL B CA   1 
ATOM   7573  C C    . VAL B 1 166 ? 8.897   28.156  33.655 1.00 13.20 ?  132  VAL B C    1 
ATOM   7574  O O    . VAL B 1 166 ? 8.599   29.306  33.355 1.00 14.34 ?  132  VAL B O    1 
ATOM   7575  C CB   . VAL B 1 166 ? 11.078  27.579  34.831 1.00 13.72 ?  132  VAL B CB   1 
ATOM   7576  C CG1  . VAL B 1 166 ? 12.451  26.928  34.636 1.00 18.59 ?  132  VAL B CG1  1 
ATOM   7577  C CG2  . VAL B 1 166 ? 11.231  28.952  35.439 1.00 15.41 ?  132  VAL B CG2  1 
ATOM   7578  H H    . VAL B 1 166 ? 11.127  29.220  32.709 1.00 17.77 ?  132  VAL B H    1 
ATOM   7579  H HA   . VAL B 1 166 ? 10.272  26.705  33.194 1.00 17.18 ?  132  VAL B HA   1 
ATOM   7580  H HB   . VAL B 1 166 ? 10.556  27.048  35.453 1.00 16.47 ?  132  VAL B HB   1 
ATOM   7581  H HG11 . VAL B 1 166 ? 12.959  27.008  35.458 1.00 22.31 ?  132  VAL B HG11 1 
ATOM   7582  H HG12 . VAL B 1 166 ? 12.328  25.992  34.413 1.00 22.31 ?  132  VAL B HG12 1 
ATOM   7583  H HG13 . VAL B 1 166 ? 12.916  27.381  33.915 1.00 22.31 ?  132  VAL B HG13 1 
ATOM   7584  H HG21 . VAL B 1 166 ? 11.781  28.885  36.235 1.00 18.49 ?  132  VAL B HG21 1 
ATOM   7585  H HG22 . VAL B 1 166 ? 11.656  29.538  34.793 1.00 18.49 ?  132  VAL B HG22 1 
ATOM   7586  H HG23 . VAL B 1 166 ? 10.354  29.295  35.670 1.00 18.49 ?  132  VAL B HG23 1 
ATOM   7587  N N    . TYR B 1 167 ? 8.013   27.290  34.132 1.00 12.97 ?  133  TYR B N    1 
ATOM   7588  C CA   . TYR B 1 167 ? 6.588   27.558  34.052 1.00 12.38 ?  133  TYR B CA   1 
ATOM   7589  C C    . TYR B 1 167 ? 5.860   27.194  35.327 1.00 11.91 ?  133  TYR B C    1 
ATOM   7590  O O    . TYR B 1 167 ? 6.281   26.376  36.145 1.00 13.44 ?  133  TYR B O    1 
ATOM   7591  C CB   . TYR B 1 167 ? 6.000   26.728  32.923 1.00 13.48 ?  133  TYR B CB   1 
ATOM   7592  C CG   . TYR B 1 167 ? 6.531   27.079  31.579 1.00 13.73 ?  133  TYR B CG   1 
ATOM   7593  C CD1  . TYR B 1 167 ? 6.088   28.191  30.916 1.00 16.05 ?  133  TYR B CD1  1 
ATOM   7594  C CD2  . TYR B 1 167 ? 7.456   26.252  30.945 1.00 18.33 ?  133  TYR B CD2  1 
ATOM   7595  C CE1  . TYR B 1 167 ? 6.561   28.517  29.641 1.00 20.59 ?  133  TYR B CE1  1 
ATOM   7596  C CE2  . TYR B 1 167 ? 7.911   26.552  29.687 1.00 21.57 ?  133  TYR B CE2  1 
ATOM   7597  C CZ   . TYR B 1 167 ? 7.462   27.668  29.058 1.00 20.70 ?  133  TYR B CZ   1 
ATOM   7598  O OH   . TYR B 1 167 ? 7.916   27.954  27.787 1.00 34.36 ?  133  TYR B OH   1 
ATOM   7599  H H    . TYR B 1 167 ? 8.216   26.542  34.505 1.00 15.57 ?  133  TYR B H    1 
ATOM   7600  H HA   . TYR B 1 167 ? 6.462   28.512  33.924 1.00 14.86 ?  133  TYR B HA   1 
ATOM   7601  H HB2  . TYR B 1 167 ? 6.201   25.793  33.086 1.00 16.17 ?  133  TYR B HB2  1 
ATOM   7602  H HB3  . TYR B 1 167 ? 5.039   26.862  32.906 1.00 16.17 ?  133  TYR B HB3  1 
ATOM   7603  H HD1  . TYR B 1 167 ? 5.459   28.742  31.323 1.00 19.26 ?  133  TYR B HD1  1 
ATOM   7604  H HD2  . TYR B 1 167 ? 7.766   25.490  31.379 1.00 22.00 ?  133  TYR B HD2  1 
ATOM   7605  H HE1  . TYR B 1 167 ? 6.272   29.285  29.203 1.00 24.71 ?  133  TYR B HE1  1 
ATOM   7606  H HE2  . TYR B 1 167 ? 8.525   25.994  29.267 1.00 25.89 ?  133  TYR B HE2  1 
ATOM   7607  H HH   . TYR B 1 167 ? 7.566   28.666  27.511 1.00 41.23 ?  133  TYR B HH   1 
ATOM   7608  N N    . MET B 1 168 ? 4.678   27.768  35.444 1.00 12.19 ?  134  MET B N    1 
ATOM   7609  C CA   . MET B 1 168 ? 3.660   27.290  36.335 1.00 12.55 ?  134  MET B CA   1 
ATOM   7610  C C    . MET B 1 168 ? 3.166   25.887  36.013 1.00 11.97 ?  134  MET B C    1 
ATOM   7611  O O    . MET B 1 168 ? 3.539   25.333  34.981 1.00 12.65 ?  134  MET B O    1 
ATOM   7612  C CB   . MET B 1 168 ? 2.446   28.272  36.420 1.00 11.17 ?  134  MET B CB   1 
ATOM   7613  C CG   . MET B 1 168 ? 2.894   29.601  36.946 1.00 12.63 ?  134  MET B CG   1 
ATOM   7614  S SD   . MET B 1 168 ? 2.913   29.482  38.776 1.00 12.82 ?  134  MET B SD   1 
ATOM   7615  C CE   . MET B 1 168 ? 1.073   29.471  39.100 1.00 14.27 ?  134  MET B CE   1 
ATOM   7616  H H    . MET B 1 168 ? 4.438   28.464  34.998 1.00 14.62 ?  134  MET B H    1 
ATOM   7617  H HA   . MET B 1 168 ? 4.089   27.249  37.203 1.00 15.06 ?  134  MET B HA   1 
ATOM   7618  H HB2  . MET B 1 168 ? 2.067   28.399  35.536 1.00 13.41 ?  134  MET B HB2  1 
ATOM   7619  H HB3  . MET B 1 168 ? 1.775   27.910  37.020 1.00 13.41 ?  134  MET B HB3  1 
ATOM   7620  H HG2  . MET B 1 168 ? 3.787   29.806  36.627 1.00 15.15 ?  134  MET B HG2  1 
ATOM   7621  H HG3  . MET B 1 168 ? 2.276   30.298  36.674 1.00 15.15 ?  134  MET B HG3  1 
ATOM   7622  H HE1  . MET B 1 168 ? 0.922   29.417  40.056 1.00 17.13 ?  134  MET B HE1  1 
ATOM   7623  H HE2  . MET B 1 168 ? 0.686   30.289  38.749 1.00 17.13 ?  134  MET B HE2  1 
ATOM   7624  H HE3  . MET B 1 168 ? 0.679   28.703  38.658 1.00 17.13 ?  134  MET B HE3  1 
ATOM   7625  N N    . PRO B 1 169 ? 2.301   25.306  36.845 1.00 11.31 ?  135  PRO B N    1 
ATOM   7626  C CA   . PRO B 1 169 ? 1.859   23.927  36.577 1.00 12.53 ?  135  PRO B CA   1 
ATOM   7627  C C    . PRO B 1 169 ? 1.181   23.753  35.254 1.00 12.33 ?  135  PRO B C    1 
ATOM   7628  O O    . PRO B 1 169 ? 1.221   22.606  34.735 1.00 13.69 ?  135  PRO B O    1 
ATOM   7629  C CB   . PRO B 1 169 ? 0.933   23.618  37.764 1.00 12.27 ?  135  PRO B CB   1 
ATOM   7630  C CG   . PRO B 1 169 ? 1.513   24.431  38.881 1.00 13.06 ?  135  PRO B CG   1 
ATOM   7631  C CD   . PRO B 1 169 ? 1.906   25.738  38.212 1.00 11.72 ?  135  PRO B CD   1 
ATOM   7632  H HA   . PRO B 1 169 ? 2.614   23.319  36.612 1.00 15.03 ?  135  PRO B HA   1 
ATOM   7633  H HB2  . PRO B 1 169 ? 0.024   23.893  37.563 1.00 14.73 ?  135  PRO B HB2  1 
ATOM   7634  H HB3  . PRO B 1 169 ? 0.954   22.670  37.970 1.00 14.73 ?  135  PRO B HB3  1 
ATOM   7635  H HG2  . PRO B 1 169 ? 0.847   24.576  39.571 1.00 15.68 ?  135  PRO B HG2  1 
ATOM   7636  H HG3  . PRO B 1 169 ? 2.287   23.982  39.256 1.00 15.68 ?  135  PRO B HG3  1 
ATOM   7637  H HD2  . PRO B 1 169 ? 1.155   26.350  38.180 1.00 14.07 ?  135  PRO B HD2  1 
ATOM   7638  H HD3  . PRO B 1 169 ? 2.652   26.153  38.674 1.00 14.07 ?  135  PRO B HD3  1 
ATOM   7639  N N    . ASN B 1 170 ? 0.600   24.789  34.656 1.00 11.27 ?  136  ASN B N    1 
ATOM   7640  C CA   . ASN B 1 170 ? -0.015  24.659  33.343 1.00 11.96 ?  136  ASN B CA   1 
ATOM   7641  C C    . ASN B 1 170 ? 1.023   24.484  32.238 1.00 11.56 ?  136  ASN B C    1 
ATOM   7642  O O    . ASN B 1 170 ? 0.630   24.229  31.095 1.00 12.97 ?  136  ASN B O    1 
ATOM   7643  C CB   . ASN B 1 170 ? -0.980  25.802  33.030 1.00 12.02 ?  136  ASN B CB   1 
ATOM   7644  C CG   . ASN B 1 170 ? -0.316  27.140  33.012 1.00 12.55 ?  136  ASN B CG   1 
ATOM   7645  O OD1  . ASN B 1 170 ? 0.879   27.290  32.797 1.00 12.98 ?  136  ASN B OD1  1 
ATOM   7646  N ND2  . ASN B 1 170 ? -1.141  28.186  33.241 1.00 17.44 ?  136  ASN B ND2  1 
ATOM   7647  H H    . ASN B 1 170 ? 0.549   25.579  34.992 1.00 13.52 ?  136  ASN B H    1 
ATOM   7648  H HA   . ASN B 1 170 ? -0.576  23.867  33.352 1.00 14.35 ?  136  ASN B HA   1 
ATOM   7649  H HB2  . ASN B 1 170 ? -1.374  25.652  32.156 1.00 14.43 ?  136  ASN B HB2  1 
ATOM   7650  H HB3  . ASN B 1 170 ? -1.674  25.822  33.708 1.00 14.43 ?  136  ASN B HB3  1 
ATOM   7651  H HD21 . ASN B 1 170 ? -0.828  28.987  33.246 1.00 20.92 ?  136  ASN B HD21 1 
ATOM   7652  H HD22 . ASN B 1 170 ? -1.978  28.051  33.382 1.00 20.92 ?  136  ASN B HD22 1 
ATOM   7653  N N    . GLY B 1 171 ? 2.308   24.648  32.554 1.00 11.52 ?  137  GLY B N    1 
ATOM   7654  C CA   . GLY B 1 171 ? 3.347   24.455  31.552 1.00 11.59 ?  137  GLY B CA   1 
ATOM   7655  C C    . GLY B 1 171 ? 3.464   25.522  30.506 1.00 12.50 ?  137  GLY B C    1 
ATOM   7656  O O    . GLY B 1 171 ? 4.208   25.351  29.529 1.00 13.21 ?  137  GLY B O    1 
ATOM   7657  H H    . GLY B 1 171 ? 2.598   24.869  33.334 1.00 13.83 ?  137  GLY B H    1 
ATOM   7658  H HA2  . GLY B 1 171 ? 4.203   24.400  32.006 1.00 13.91 ?  137  GLY B HA2  1 
ATOM   7659  H HA3  . GLY B 1 171 ? 3.178   23.617  31.094 1.00 13.91 ?  137  GLY B HA3  1 
ATOM   7660  N N    . SER B 1 172 ? 2.742   26.629  30.652 1.00 12.38 ?  138  SER B N    1 
ATOM   7661  C CA   . SER B 1 172 ? 2.669   27.684  29.644 1.00 12.09 ?  138  SER B CA   1 
ATOM   7662  C C    . SER B 1 172 ? 2.830   29.083  30.224 1.00 13.15 ?  138  SER B C    1 
ATOM   7663  O O    . SER B 1 172 ? 3.315   29.968  29.518 1.00 15.04 ?  138  SER B O    1 
ATOM   7664  C CB   . SER B 1 172 ? 1.357   27.552  28.888 1.00 16.22 ?  138  SER B CB   1 
ATOM   7665  O OG   . SER B 1 172 ? 1.488   28.246  27.653 1.00 23.72 ?  138  SER B OG   1 
ATOM   7666  H H    . SER B 1 172 ? 2.268   26.800  31.349 1.00 14.85 ?  138  SER B H    1 
ATOM   7667  H HA   . SER B 1 172 ? 3.412   27.577  29.029 1.00 14.51 ?  138  SER B HA   1 
ATOM   7668  H HB2  . SER B 1 172 ? 1.171   26.615  28.718 1.00 19.46 ?  138  SER B HB2  1 
ATOM   7669  H HB3  . SER B 1 172 ? 0.639   27.943  29.409 1.00 19.46 ?  138  SER B HB3  1 
ATOM   7670  H HG   . SER B 1 172 ? 0.773   28.190  27.215 1.00 28.47 ?  138  SER B HG   1 
ATOM   7671  N N    . THR B 1 173 ? 2.402   29.313  31.454 1.00 12.43 ?  139  THR B N    1 
ATOM   7672  C CA   . THR B 1 173 ? 2.517   30.649  32.053 1.00 12.33 ?  139  THR B CA   1 
ATOM   7673  C C    . THR B 1 173 ? 3.899   30.774  32.670 1.00 11.92 ?  139  THR B C    1 
ATOM   7674  O O    . THR B 1 173 ? 4.230   29.975  33.551 1.00 12.94 ?  139  THR B O    1 
ATOM   7675  C CB   . THR B 1 173 ? 1.466   30.840  33.127 1.00 11.08 ?  139  THR B CB   1 
ATOM   7676  O OG1  . THR B 1 173 ? 0.163   30.667  32.561 1.00 13.93 ?  139  THR B OG1  1 
ATOM   7677  C CG2  . THR B 1 173 ? 1.604   32.215  33.767 1.00 14.21 ?  139  THR B CG2  1 
ATOM   7678  H H    . THR B 1 173 ? 2.042   28.722  31.965 1.00 14.91 ?  139  THR B H    1 
ATOM   7679  H HA   . THR B 1 173 ? 2.395   31.336  31.379 1.00 14.80 ?  139  THR B HA   1 
ATOM   7680  H HB   . THR B 1 173 ? 1.583   30.181  33.830 1.00 13.29 ?  139  THR B HB   1 
ATOM   7681  H HG1  . THR B 1 173 ? 0.058   31.194  31.915 1.00 16.71 ?  139  THR B HG1  1 
ATOM   7682  H HG21 . THR B 1 173 ? 0.899   32.349  34.420 1.00 17.06 ?  139  THR B HG21 1 
ATOM   7683  H HG22 . THR B 1 173 ? 2.463   32.289  34.212 1.00 17.06 ?  139  THR B HG22 1 
ATOM   7684  H HG23 . THR B 1 173 ? 1.540   32.905  33.089 1.00 17.06 ?  139  THR B HG23 1 
ATOM   7685  N N    . PRO B 1 174 ? 4.724   31.737  32.218 1.00 11.74 ?  140  PRO B N    1 
ATOM   7686  C CA   . PRO B 1 174 ? 6.098   31.859  32.706 1.00 12.44 ?  140  PRO B CA   1 
ATOM   7687  C C    . PRO B 1 174 ? 6.173   32.898  33.809 1.00 12.81 ?  140  PRO B C    1 
ATOM   7688  O O    . PRO B 1 174 ? 5.127   33.353  34.326 1.00 13.29 ?  140  PRO B O    1 
ATOM   7689  C CB   . PRO B 1 174 ? 6.827   32.296  31.440 1.00 13.64 ?  140  PRO B CB   1 
ATOM   7690  C CG   . PRO B 1 174 ? 5.873   33.219  30.767 1.00 13.94 ?  140  PRO B CG   1 
ATOM   7691  C CD   . PRO B 1 174 ? 4.458   32.651  31.085 1.00 12.91 ?  140  PRO B CD   1 
ATOM   7692  H HA   . PRO B 1 174 ? 6.472   31.022  33.020 1.00 14.93 ?  140  PRO B HA   1 
ATOM   7693  H HB2  . PRO B 1 174 ? 7.651   32.753  31.671 1.00 16.37 ?  140  PRO B HB2  1 
ATOM   7694  H HB3  . PRO B 1 174 ? 7.020   31.525  30.884 1.00 16.37 ?  140  PRO B HB3  1 
ATOM   7695  H HG2  . PRO B 1 174 ? 5.974   34.115  31.125 1.00 16.73 ?  140  PRO B HG2  1 
ATOM   7696  H HG3  . PRO B 1 174 ? 6.037   33.222  29.811 1.00 16.73 ?  140  PRO B HG3  1 
ATOM   7697  H HD2  . PRO B 1 174 ? 3.849   33.360  31.345 1.00 15.50 ?  140  PRO B HD2  1 
ATOM   7698  H HD3  . PRO B 1 174 ? 4.098   32.168  30.325 1.00 15.50 ?  140  PRO B HD3  1 
ATOM   7699  N N    . PHE B 1 175 ? 7.396   33.212  34.237 1.00 12.32 ?  141  PHE B N    1 
ATOM   7700  C CA   . PHE B 1 175 ? 7.654   34.118  35.353 1.00 12.42 ?  141  PHE B CA   1 
ATOM   7701  C C    . PHE B 1 175 ? 8.534   35.283  34.901 1.00 13.69 ?  141  PHE B C    1 
ATOM   7702  O O    . PHE B 1 175 ? 9.359   35.150  33.991 1.00 14.14 ?  141  PHE B O    1 
ATOM   7703  C CB   . PHE B 1 175 ? 8.399   33.416  36.494 1.00 13.26 ?  141  PHE B CB   1 
ATOM   7704  C CG   . PHE B 1 175 ? 7.711   32.180  37.023 1.00 12.29 ?  141  PHE B CG   1 
ATOM   7705  C CD1  . PHE B 1 175 ? 6.778   32.261  38.068 1.00 11.87 ?  141  PHE B CD1  1 
ATOM   7706  C CD2  . PHE B 1 175 ? 7.990   30.930  36.488 1.00 12.79 ?  141  PHE B CD2  1 
ATOM   7707  C CE1  . PHE B 1 175 ? 6.174   31.144  38.558 1.00 12.78 ?  141  PHE B CE1  1 
ATOM   7708  C CE2  . PHE B 1 175 ? 7.362   29.811  36.963 1.00 13.07 ?  141  PHE B CE2  1 
ATOM   7709  C CZ   . PHE B 1 175 ? 6.475   29.898  38.021 1.00 11.94 ?  141  PHE B CZ   1 
ATOM   7710  H H    . PHE B 1 175 ? 8.116   32.900  33.883 1.00 14.79 ?  141  PHE B H    1 
ATOM   7711  H HA   . PHE B 1 175 ? 6.800   34.451  35.670 1.00 14.91 ?  141  PHE B HA   1 
ATOM   7712  H HB2  . PHE B 1 175 ? 9.275   33.150  36.173 1.00 15.91 ?  141  PHE B HB2  1 
ATOM   7713  H HB3  . PHE B 1 175 ? 8.491   34.039  37.232 1.00 15.91 ?  141  PHE B HB3  1 
ATOM   7714  H HD1  . PHE B 1 175 ? 6.569   33.091  38.432 1.00 14.25 ?  141  PHE B HD1  1 
ATOM   7715  H HD2  . PHE B 1 175 ? 8.610   30.853  35.800 1.00 15.35 ?  141  PHE B HD2  1 
ATOM   7716  H HE1  . PHE B 1 175 ? 5.559   31.214  39.253 1.00 15.33 ?  141  PHE B HE1  1 
ATOM   7717  H HE2  . PHE B 1 175 ? 7.534   28.985  36.571 1.00 15.69 ?  141  PHE B HE2  1 
ATOM   7718  H HZ   . PHE B 1 175 ? 6.084   29.129  38.370 1.00 14.33 ?  141  PHE B HZ   1 
ATOM   7719  N N    . PHE B 1 176 ? 8.328   36.454  35.511 1.00 14.00 ?  142  PHE B N    1 
ATOM   7720  C CA   . PHE B 1 176 ? 9.259   37.572  35.360 1.00 13.28 ?  142  PHE B CA   1 
ATOM   7721  C C    . PHE B 1 176 ? 10.552  37.245  36.080 1.00 13.17 ?  142  PHE B C    1 
ATOM   7722  O O    . PHE B 1 176 ? 10.511  36.793  37.226 1.00 15.60 ?  142  PHE B O    1 
ATOM   7723  C CB   . PHE B 1 176 ? 8.679   38.853  35.993 1.00 14.18 ?  142  PHE B CB   1 
ATOM   7724  C CG   . PHE B 1 176 ? 7.333   39.279  35.459 1.00 14.46 ?  142  PHE B CG   1 
ATOM   7725  C CD1  . PHE B 1 176 ? 7.161   39.604  34.137 1.00 16.49 ?  142  PHE B CD1  1 
ATOM   7726  C CD2  . PHE B 1 176 ? 6.276   39.386  36.322 1.00 14.60 ?  142  PHE B CD2  1 
ATOM   7727  C CE1  . PHE B 1 176 ? 5.921   40.025  33.687 1.00 20.16 ?  142  PHE B CE1  1 
ATOM   7728  C CE2  . PHE B 1 176 ? 5.039   39.795  35.880 1.00 15.17 ?  142  PHE B CE2  1 
ATOM   7729  C CZ   . PHE B 1 176 ? 4.872   40.120  34.589 1.00 15.90 ?  142  PHE B CZ   1 
ATOM   7730  H H    . PHE B 1 176 ? 7.656   36.627  36.018 1.00 16.80 ?  142  PHE B H    1 
ATOM   7731  H HA   . PHE B 1 176 ? 9.419   37.724  34.415 1.00 15.94 ?  142  PHE B HA   1 
ATOM   7732  H HB2  . PHE B 1 176 ? 8.580   38.705  36.946 1.00 17.01 ?  142  PHE B HB2  1 
ATOM   7733  H HB3  . PHE B 1 176 ? 9.298   39.581  35.832 1.00 17.01 ?  142  PHE B HB3  1 
ATOM   7734  H HD1  . PHE B 1 176 ? 7.876   39.542  33.545 1.00 19.79 ?  142  PHE B HD1  1 
ATOM   7735  H HD2  . PHE B 1 176 ? 6.396   39.179  37.221 1.00 17.52 ?  142  PHE B HD2  1 
ATOM   7736  H HE1  . PHE B 1 176 ? 5.793   40.242  32.792 1.00 24.19 ?  142  PHE B HE1  1 
ATOM   7737  H HE2  . PHE B 1 176 ? 4.323   39.845  36.472 1.00 18.20 ?  142  PHE B HE2  1 
ATOM   7738  H HZ   . PHE B 1 176 ? 4.040   40.413  34.295 1.00 19.08 ?  142  PHE B HZ   1 
ATOM   7739  N N    . ASP B 1 177 ? 11.694  37.491  35.415 1.00 14.33 ?  143  ASP B N    1 
ATOM   7740  C CA   . ASP B 1 177 ? 12.984  37.399  36.100 1.00 14.93 ?  143  ASP B CA   1 
ATOM   7741  C C    . ASP B 1 177 ? 13.246  38.714  36.817 1.00 14.68 ?  143  ASP B C    1 
ATOM   7742  O O    . ASP B 1 177 ? 13.873  39.620  36.255 1.00 16.14 ?  143  ASP B O    1 
ATOM   7743  C CB   . ASP B 1 177 ? 14.136  37.058  35.168 1.00 17.65 ?  143  ASP B CB   1 
ATOM   7744  C CG   . ASP B 1 177 ? 15.414  36.846  35.942 1.00 16.75 ?  143  ASP B CG   1 
ATOM   7745  O OD1  . ASP B 1 177 ? 15.441  37.105  37.147 1.00 17.15 ?  143  ASP B OD1  1 
ATOM   7746  O OD2  . ASP B 1 177 ? 16.393  36.298  35.353 1.00 20.23 ?  143  ASP B OD2  1 
ATOM   7747  H H    . ASP B 1 177 ? 11.741  37.707  34.584 1.00 17.20 ?  143  ASP B H    1 
ATOM   7748  H HA   . ASP B 1 177 ? 12.912  36.680  36.747 1.00 17.92 ?  143  ASP B HA   1 
ATOM   7749  H HB2  . ASP B 1 177 ? 13.930  36.242  34.685 1.00 21.18 ?  143  ASP B HB2  1 
ATOM   7750  H HB3  . ASP B 1 177 ? 14.273  37.788  34.543 1.00 21.18 ?  143  ASP B HB3  1 
ATOM   7751  N N    . ILE B 1 178 ? 12.752  38.812  38.042 1.00 14.11 ?  144  ILE B N    1 
ATOM   7752  C CA   . ILE B 1 178 ? 12.853  40.060  38.784 1.00 14.38 ?  144  ILE B CA   1 
ATOM   7753  C C    . ILE B 1 178 ? 14.257  40.334  39.294 1.00 16.42 ?  144  ILE B C    1 
ATOM   7754  O O    . ILE B 1 178 ? 14.477  41.365  39.941 1.00 15.78 ?  144  ILE B O    1 
ATOM   7755  C CB   . ILE B 1 178 ? 11.817  40.156  39.915 1.00 15.27 ?  144  ILE B CB   1 
ATOM   7756  C CG1  . ILE B 1 178 ? 11.992  39.064  40.957 1.00 15.37 ?  144  ILE B CG1  1 
ATOM   7757  C CG2  . ILE B 1 178 ? 10.388  40.096  39.333 1.00 16.49 ?  144  ILE B CG2  1 
ATOM   7758  C CD1  . ILE B 1 178 ? 11.189  39.267  42.222 1.00 15.98 ?  144  ILE B CD1  1 
ATOM   7759  H H    . ILE B 1 178 ? 12.357  38.175  38.463 1.00 16.93 ?  144  ILE B H    1 
ATOM   7760  H HA   . ILE B 1 178 ? 12.667  40.760  38.139 1.00 17.26 ?  144  ILE B HA   1 
ATOM   7761  H HB   . ILE B 1 178 ? 11.961  41.007  40.357 1.00 18.32 ?  144  ILE B HB   1 
ATOM   7762  H HG12 . ILE B 1 178 ? 11.716  38.219  40.568 1.00 18.45 ?  144  ILE B HG12 1 
ATOM   7763  H HG13 . ILE B 1 178 ? 12.928  39.024  41.208 1.00 18.45 ?  144  ILE B HG13 1 
ATOM   7764  H HG21 . ILE B 1 178 ? 9.752   40.299  40.036 1.00 19.78 ?  144  ILE B HG21 1 
ATOM   7765  H HG22 . ILE B 1 178 ? 10.311  40.747  38.618 1.00 19.78 ?  144  ILE B HG22 1 
ATOM   7766  H HG23 . ILE B 1 178 ? 10.225  39.204  38.987 1.00 19.78 ?  144  ILE B HG23 1 
ATOM   7767  H HD11 . ILE B 1 178 ? 11.361  38.528  42.827 1.00 19.18 ?  144  ILE B HD11 1 
ATOM   7768  H HD12 . ILE B 1 178 ? 11.457  40.102  42.635 1.00 19.18 ?  144  ILE B HD12 1 
ATOM   7769  H HD13 . ILE B 1 178 ? 10.246  39.297  41.996 1.00 19.18 ?  144  ILE B HD13 1 
ATOM   7770  N N    . THR B 1 179 ? 15.227  39.439  39.036 1.00 16.10 ?  145  THR B N    1 
ATOM   7771  C CA   . THR B 1 179 ? 16.620  39.763  39.365 1.00 16.47 ?  145  THR B CA   1 
ATOM   7772  C C    . THR B 1 179 ? 17.185  40.775  38.411 1.00 17.35 ?  145  THR B C    1 
ATOM   7773  O O    . THR B 1 179 ? 18.222  41.395  38.736 1.00 17.39 ?  145  THR B O    1 
ATOM   7774  C CB   . THR B 1 179 ? 17.520  38.506  39.350 1.00 16.57 ?  145  THR B CB   1 
ATOM   7775  O OG1  . THR B 1 179 ? 17.767  38.090  38.003 1.00 17.62 ?  145  THR B OG1  1 
ATOM   7776  C CG2  . THR B 1 179 ? 16.942  37.402  40.189 1.00 18.99 ?  145  THR B CG2  1 
ATOM   7777  H H    . THR B 1 179 ? 15.106  38.664  38.682 1.00 19.32 ?  145  THR B H    1 
ATOM   7778  H HA   . THR B 1 179 ? 16.636  40.117  40.268 1.00 19.76 ?  145  THR B HA   1 
ATOM   7779  H HB   . THR B 1 179 ? 18.378  38.719  39.749 1.00 19.88 ?  145  THR B HB   1 
ATOM   7780  H HG1  . THR B 1 179 ? 17.079  38.208  37.535 1.00 21.14 ?  145  THR B HG1  1 
ATOM   7781  H HG21 . THR B 1 179 ? 17.535  36.634  40.181 1.00 22.79 ?  145  THR B HG21 1 
ATOM   7782  H HG22 . THR B 1 179 ? 16.829  37.704  41.103 1.00 22.79 ?  145  THR B HG22 1 
ATOM   7783  H HG23 . THR B 1 179 ? 16.078  37.135  39.837 1.00 22.79 ?  145  THR B HG23 1 
ATOM   7784  N N    . LYS B 1 180 ? 16.565  41.005  37.274 1.00 15.21 ?  146  LYS B N    1 
ATOM   7785  C CA   . LYS B 1 180 ? 17.060  41.963  36.304 1.00 17.75 ?  146  LYS B CA   1 
ATOM   7786  C C    . LYS B 1 180 ? 16.510  43.355  36.561 1.00 18.40 ?  146  LYS B C    1 
ATOM   7787  O O    . LYS B 1 180 ? 15.295  43.523  36.720 1.00 17.50 ?  146  LYS B O    1 
ATOM   7788  C CB   . LYS B 1 180 ? 16.720  41.516  34.895 1.00 17.36 ?  146  LYS B CB   1 
ATOM   7789  C CG   . LYS B 1 180 ? 17.318  40.144  34.614 1.00 19.10 ?  146  LYS B CG   1 
ATOM   7790  C CD   . LYS B 1 180 ? 17.114  39.655  33.233 1.00 19.84 ?  146  LYS B CD   1 
ATOM   7791  C CE   . LYS B 1 180 ? 17.779  38.303  33.033 1.00 22.46 ?  146  LYS B CE   1 
ATOM   7792  N NZ   . LYS B 1 180 ? 17.670  37.838  31.652 1.00 26.48 ?  146  LYS B NZ   1 
ATOM   7793  H H    . LYS B 1 180 ? 15.840  40.611  37.033 1.00 18.25 ?  146  LYS B H    1 
ATOM   7794  H HA   . LYS B 1 180 ? 18.024  42.017  36.394 1.00 21.30 ?  146  LYS B HA   1 
ATOM   7795  H HB2  . LYS B 1 180 ? 15.756  41.461  34.796 1.00 20.83 ?  146  LYS B HB2  1 
ATOM   7796  H HB3  . LYS B 1 180 ? 17.083  42.150  34.257 1.00 20.83 ?  146  LYS B HB3  1 
ATOM   7797  H HG2  . LYS B 1 180 ? 18.274  40.186  34.770 1.00 22.92 ?  146  LYS B HG2  1 
ATOM   7798  H HG3  . LYS B 1 180 ? 16.911  39.500  35.214 1.00 22.92 ?  146  LYS B HG3  1 
ATOM   7799  H HD2  . LYS B 1 180 ? 16.164  39.559  33.061 1.00 23.81 ?  146  LYS B HD2  1 
ATOM   7800  H HD3  . LYS B 1 180 ? 17.502  40.285  32.606 1.00 23.81 ?  146  LYS B HD3  1 
ATOM   7801  H HE2  . LYS B 1 180 ? 18.720  38.375  33.255 1.00 26.95 ?  146  LYS B HE2  1 
ATOM   7802  H HE3  . LYS B 1 180 ? 17.351  37.649  33.607 1.00 26.95 ?  146  LYS B HE3  1 
ATOM   7803  H HZ1  . LYS B 1 180 ? 16.814  37.729  31.434 1.00 31.77 ?  146  LYS B HZ1  1 
ATOM   7804  H HZ2  . LYS B 1 180 ? 18.035  38.434  31.101 1.00 31.77 ?  146  LYS B HZ2  1 
ATOM   7805  H HZ3  . LYS B 1 180 ? 18.093  37.061  31.559 1.00 31.77 ?  146  LYS B HZ3  1 
ATOM   7806  N N    . SER B 1 181 ? 17.405  44.346  36.593 1.00 18.99 ?  147  SER B N    1 
ATOM   7807  C CA   . SER B 1 181 ? 16.984  45.696  36.932 1.00 17.28 ?  147  SER B CA   1 
ATOM   7808  C C    . SER B 1 181 ? 15.892  46.189  36.003 1.00 18.48 ?  147  SER B C    1 
ATOM   7809  O O    . SER B 1 181 ? 14.930  46.799  36.469 1.00 16.95 ?  147  SER B O    1 
ATOM   7810  C CB   . SER B 1 181 ? 18.177  46.658  36.913 1.00 22.58 ?  147  SER B CB   1 
ATOM   7811  O OG   . SER B 1 181 ? 19.045  46.341  37.974 1.00 27.36 ?  147  SER B OG   1 
ATOM   7812  H H    . SER B 1 181 ? 18.244  44.260  36.425 1.00 22.78 ?  147  SER B H    1 
ATOM   7813  H HA   . SER B 1 181 ? 16.629  45.681  37.835 1.00 20.73 ?  147  SER B HA   1 
ATOM   7814  H HB2  . SER B 1 181 ? 18.650  46.567  36.071 1.00 27.10 ?  147  SER B HB2  1 
ATOM   7815  H HB3  . SER B 1 181 ? 17.859  47.568  37.018 1.00 27.10 ?  147  SER B HB3  1 
ATOM   7816  H HG   . SER B 1 181 ? 19.677  46.894  38.004 1.00 32.83 ?  147  SER B HG   1 
ATOM   7817  N N    . PHE B 1 182 ? 16.004  45.966  34.687 1.00 15.80 ?  148  PHE B N    1 
ATOM   7818  C CA   . PHE B 1 182 ? 15.013  46.526  33.778 1.00 16.17 ?  148  PHE B CA   1 
ATOM   7819  C C    . PHE B 1 182 ? 13.634  45.919  34.021 1.00 16.87 ?  148  PHE B C    1 
ATOM   7820  O O    . PHE B 1 182 ? 12.613  46.569  33.776 1.00 16.99 ?  148  PHE B O    1 
ATOM   7821  C CB   . PHE B 1 182 ? 15.458  46.450  32.314 1.00 18.11 ?  148  PHE B CB   1 
ATOM   7822  C CG   . PHE B 1 182 ? 15.247  45.108  31.664 1.00 19.78 ?  148  PHE B CG   1 
ATOM   7823  C CD1  . PHE B 1 182 ? 16.209  44.090  31.752 1.00 20.24 ?  148  PHE B CD1  1 
ATOM   7824  C CD2  . PHE B 1 182 ? 14.108  44.871  30.900 1.00 20.37 ?  148  PHE B CD2  1 
ATOM   7825  C CE1  . PHE B 1 182 ? 16.009  42.870  31.126 1.00 20.69 ?  148  PHE B CE1  1 
ATOM   7826  C CE2  . PHE B 1 182 ? 13.907  43.646  30.269 1.00 21.02 ?  148  PHE B CE2  1 
ATOM   7827  C CZ   . PHE B 1 182 ? 14.856  42.657  30.383 1.00 19.55 ?  148  PHE B CZ   1 
ATOM   7828  H H    . PHE B 1 182 ? 16.627  45.507  34.312 1.00 18.96 ?  148  PHE B H    1 
ATOM   7829  H HA   . PHE B 1 182 ? 14.938  47.477  33.950 1.00 19.40 ?  148  PHE B HA   1 
ATOM   7830  H HB2  . PHE B 1 182 ? 14.955  47.104  31.804 1.00 21.73 ?  148  PHE B HB2  1 
ATOM   7831  H HB3  . PHE B 1 182 ? 16.406  46.651  32.269 1.00 21.73 ?  148  PHE B HB3  1 
ATOM   7832  H HD1  . PHE B 1 182 ? 16.990  44.236  32.236 1.00 24.29 ?  148  PHE B HD1  1 
ATOM   7833  H HD2  . PHE B 1 182 ? 13.470  45.542  30.809 1.00 24.44 ?  148  PHE B HD2  1 
ATOM   7834  H HE1  . PHE B 1 182 ? 16.646  42.196  31.203 1.00 24.83 ?  148  PHE B HE1  1 
ATOM   7835  H HE2  . PHE B 1 182 ? 13.135  43.497  29.773 1.00 25.23 ?  148  PHE B HE2  1 
ATOM   7836  H HZ   . PHE B 1 182 ? 14.723  41.839  29.960 1.00 23.46 ?  148  PHE B HZ   1 
ATOM   7837  N N    . VAL B 1 183 ? 13.601  44.665  34.468 1.00 16.56 ?  149  VAL B N    1 
ATOM   7838  C CA   . VAL B 1 183 ? 12.325  44.024  34.821 1.00 15.46 ?  149  VAL B CA   1 
ATOM   7839  C C    . VAL B 1 183 ? 11.754  44.643  36.092 1.00 13.67 ?  149  VAL B C    1 
ATOM   7840  O O    . VAL B 1 183 ? 10.547  44.934  36.171 1.00 14.89 ?  149  VAL B O    1 
ATOM   7841  C CB   . VAL B 1 183 ? 12.518  42.506  34.968 1.00 15.60 ?  149  VAL B CB   1 
ATOM   7842  C CG1  . VAL B 1 183 ? 11.215  41.831  35.444 1.00 17.02 ?  149  VAL B CG1  1 
ATOM   7843  C CG2  . VAL B 1 183 ? 12.973  41.916  33.651 1.00 16.70 ?  149  VAL B CG2  1 
ATOM   7844  H H    . VAL B 1 183 ? 14.292  44.165  34.577 1.00 19.87 ?  149  VAL B H    1 
ATOM   7845  H HA   . VAL B 1 183 ? 11.689  44.178  34.105 1.00 18.56 ?  149  VAL B HA   1 
ATOM   7846  H HB   . VAL B 1 183 ? 13.200  42.336  35.636 1.00 18.72 ?  149  VAL B HB   1 
ATOM   7847  H HG11 . VAL B 1 183 ? 11.348  40.870  35.469 1.00 20.43 ?  149  VAL B HG11 1 
ATOM   7848  H HG12 . VAL B 1 183 ? 10.996  42.157  36.331 1.00 20.43 ?  149  VAL B HG12 1 
ATOM   7849  H HG13 . VAL B 1 183 ? 10.501  42.050  34.826 1.00 20.43 ?  149  VAL B HG13 1 
ATOM   7850  H HG21 . VAL B 1 183 ? 13.071  40.956  33.752 1.00 20.04 ?  149  VAL B HG21 1 
ATOM   7851  H HG22 . VAL B 1 183 ? 12.310  42.111  32.971 1.00 20.04 ?  149  VAL B HG22 1 
ATOM   7852  H HG23 . VAL B 1 183 ? 13.825  42.310  33.406 1.00 20.04 ?  149  VAL B HG23 1 
ATOM   7853  N N    . GLN B 1 184 ? 12.596  44.817  37.112 1.00 14.82 ?  150  GLN B N    1 
ATOM   7854  C CA   . GLN B 1 184 ? 12.162  45.498  38.332 1.00 14.83 ?  150  GLN B CA   1 
ATOM   7855  C C    . GLN B 1 184 ? 11.538  46.846  38.011 1.00 15.92 ?  150  GLN B C    1 
ATOM   7856  O O    . GLN B 1 184 ? 10.487  47.202  38.560 1.00 15.44 ?  150  GLN B O    1 
ATOM   7857  C CB   . GLN B 1 184 ? 13.345  45.718  39.272 1.00 15.88 ?  150  GLN B CB   1 
ATOM   7858  C CG   . GLN B 1 184 ? 13.964  44.459  39.782 1.00 17.18 ?  150  GLN B CG   1 
ATOM   7859  C CD   . GLN B 1 184 ? 15.303  44.702  40.479 1.00 18.29 ?  150  GLN B CD   1 
ATOM   7860  O OE1  . GLN B 1 184 ? 15.586  45.822  40.959 1.00 20.82 ?  150  GLN B OE1  1 
ATOM   7861  N NE2  . GLN B 1 184 ? 16.112  43.671  40.574 1.00 17.38 ?  150  GLN B NE2  1 
ATOM   7862  H H    . GLN B 1 184 ? 13.415  44.554  37.123 1.00 17.78 ?  150  GLN B H    1 
ATOM   7863  H HA   . GLN B 1 184 ? 11.509  44.932  38.772 1.00 17.80 ?  150  GLN B HA   1 
ATOM   7864  H HB2  . GLN B 1 184 ? 14.031  46.212  38.797 1.00 19.05 ?  150  GLN B HB2  1 
ATOM   7865  H HB3  . GLN B 1 184 ? 13.041  46.228  40.040 1.00 19.05 ?  150  GLN B HB3  1 
ATOM   7866  H HG2  . GLN B 1 184 ? 13.363  44.047  40.422 1.00 20.62 ?  150  GLN B HG2  1 
ATOM   7867  H HG3  . GLN B 1 184 ? 14.118  43.857  39.037 1.00 20.62 ?  150  GLN B HG3  1 
ATOM   7868  H HE21 . GLN B 1 184 ? 15.877  42.909  40.252 1.00 20.86 ?  150  GLN B HE21 1 
ATOM   7869  H HE22 . GLN B 1 184 ? 16.877  43.759  40.958 1.00 20.86 ?  150  GLN B HE22 1 
ATOM   7870  N N    . GLU B 1 185 ? 12.202  47.641  37.161 1.00 15.59 ?  151  GLU B N    1 
ATOM   7871  C CA   . GLU B 1 185 ? 11.742  48.992  36.854 1.00 15.68 ?  151  GLU B CA   1 
ATOM   7872  C C    . GLU B 1 185 ? 10.463  48.957  36.065 1.00 14.99 ?  151  GLU B C    1 
ATOM   7873  O O    . GLU B 1 185 ? 9.555   49.740  36.330 1.00 17.22 ?  151  GLU B O    1 
ATOM   7874  C CB   . GLU B 1 185 ? 12.848  49.772  36.114 1.00 18.04 ?  151  GLU B CB   1 
ATOM   7875  C CG   . GLU B 1 185 ? 14.140  49.985  36.916 1.00 19.57 ?  151  GLU B CG   1 
ATOM   7876  C CD   . GLU B 1 185 ? 13.951  50.758  38.205 1.00 21.34 ?  151  GLU B CD   1 
ATOM   7877  O OE1  . GLU B 1 185 ? 13.031  51.605  38.276 1.00 22.77 ?  151  GLU B OE1  1 
ATOM   7878  O OE2  . GLU B 1 185 ? 14.689  50.478  39.176 1.00 26.45 ?  151  GLU B OE2  1 
ATOM   7879  H H    . GLU B 1 185 ? 12.924  47.418  36.750 1.00 18.70 ?  151  GLU B H    1 
ATOM   7880  H HA   . GLU B 1 185 ? 11.560  49.468  37.679 1.00 18.82 ?  151  GLU B HA   1 
ATOM   7881  H HB2  . GLU B 1 185 ? 13.082  49.284  35.310 1.00 21.65 ?  151  GLU B HB2  1 
ATOM   7882  H HB3  . GLU B 1 185 ? 12.503  50.649  35.882 1.00 21.65 ?  151  GLU B HB3  1 
ATOM   7883  H HG2  . GLU B 1 185 ? 14.510  49.118  37.144 1.00 23.48 ?  151  GLU B HG2  1 
ATOM   7884  H HG3  . GLU B 1 185 ? 14.769  50.480  36.366 1.00 23.48 ?  151  GLU B HG3  1 
ATOM   7885  N N    . TYR B 1 186 ? 10.356  48.034  35.098 1.00 14.95 ?  152  TYR B N    1 
ATOM   7886  C CA   . TYR B 1 186 ? 9.110   47.905  34.363 1.00 14.65 ?  152  TYR B CA   1 
ATOM   7887  C C    . TYR B 1 186 ? 7.962   47.560  35.313 1.00 14.70 ?  152  TYR B C    1 
ATOM   7888  O O    . TYR B 1 186 ? 6.874   48.153  35.259 1.00 14.98 ?  152  TYR B O    1 
ATOM   7889  C CB   . TYR B 1 186 ? 9.199   46.818  33.267 1.00 16.93 ?  152  TYR B CB   1 
ATOM   7890  C CG   . TYR B 1 186 ? 7.832   46.545  32.682 1.00 14.39 ?  152  TYR B CG   1 
ATOM   7891  C CD1  . TYR B 1 186 ? 7.312   47.359  31.697 1.00 15.92 ?  152  TYR B CD1  1 
ATOM   7892  C CD2  . TYR B 1 186 ? 7.027   45.514  33.167 1.00 15.08 ?  152  TYR B CD2  1 
ATOM   7893  C CE1  . TYR B 1 186 ? 6.054   47.212  31.209 1.00 15.47 ?  152  TYR B CE1  1 
ATOM   7894  C CE2  . TYR B 1 186 ? 5.763   45.315  32.657 1.00 15.23 ?  152  TYR B CE2  1 
ATOM   7895  C CZ   . TYR B 1 186 ? 5.257   46.163  31.689 1.00 15.06 ?  152  TYR B CZ   1 
ATOM   7896  O OH   . TYR B 1 186 ? 3.998   46.041  31.174 1.00 15.74 ?  152  TYR B OH   1 
ATOM   7897  H H    . TYR B 1 186 ? 10.978  47.490  34.860 1.00 17.93 ?  152  TYR B H    1 
ATOM   7898  H HA   . TYR B 1 186 ? 8.941   48.754  33.926 1.00 17.58 ?  152  TYR B HA   1 
ATOM   7899  H HB2  . TYR B 1 186 ? 9.785   47.122  32.557 1.00 20.32 ?  152  TYR B HB2  1 
ATOM   7900  H HB3  . TYR B 1 186 ? 9.541   45.997  33.653 1.00 20.32 ?  152  TYR B HB3  1 
ATOM   7901  H HD1  . TYR B 1 186 ? 7.846   48.039  31.353 1.00 19.11 ?  152  TYR B HD1  1 
ATOM   7902  H HD2  . TYR B 1 186 ? 7.346   44.958  33.841 1.00 18.09 ?  152  TYR B HD2  1 
ATOM   7903  H HE1  . TYR B 1 186 ? 5.726   47.798  30.565 1.00 18.56 ?  152  TYR B HE1  1 
ATOM   7904  H HE2  . TYR B 1 186 ? 5.247   44.606  32.966 1.00 18.27 ?  152  TYR B HE2  1 
ATOM   7905  H HH   . TYR B 1 186 ? 3.626   45.356  31.485 1.00 18.89 ?  152  TYR B HH   1 
ATOM   7906  N N    . TRP B 1 187 ? 8.201   46.616  36.206 1.00 14.47 ?  153  TRP B N    1 
ATOM   7907  C CA   . TRP B 1 187 ? 7.141   46.144  37.087 1.00 14.31 ?  153  TRP B CA   1 
ATOM   7908  C C    . TRP B 1 187 ? 6.710   47.249  38.045 1.00 13.56 ?  153  TRP B C    1 
ATOM   7909  O O    . TRP B 1 187 ? 5.507   47.517  38.204 1.00 13.92 ?  153  TRP B O    1 
ATOM   7910  C CB   . TRP B 1 187 ? 7.615   44.893  37.828 1.00 13.89 ?  153  TRP B CB   1 
ATOM   7911  C CG   . TRP B 1 187 ? 6.515   44.182  38.597 1.00 13.53 ?  153  TRP B CG   1 
ATOM   7912  C CD1  . TRP B 1 187 ? 5.748   43.144  38.155 1.00 13.08 ?  153  TRP B CD1  1 
ATOM   7913  C CD2  . TRP B 1 187 ? 6.110   44.454  39.937 1.00 13.31 ?  153  TRP B CD2  1 
ATOM   7914  N NE1  . TRP B 1 187 ? 4.874   42.774  39.153 1.00 13.08 ?  153  TRP B NE1  1 
ATOM   7915  C CE2  . TRP B 1 187 ? 5.065   43.572  40.250 1.00 11.71 ?  153  TRP B CE2  1 
ATOM   7916  C CE3  . TRP B 1 187 ? 6.525   45.380  40.907 1.00 13.19 ?  153  TRP B CE3  1 
ATOM   7917  C CZ2  . TRP B 1 187 ? 4.448   43.562  41.497 1.00 13.61 ?  153  TRP B CZ2  1 
ATOM   7918  C CZ3  . TRP B 1 187 ? 5.930   45.374  42.154 1.00 13.80 ?  153  TRP B CZ3  1 
ATOM   7919  C CH2  . TRP B 1 187 ? 4.886   44.460  42.443 1.00 14.06 ?  153  TRP B CH2  1 
ATOM   7920  H H    . TRP B 1 187 ? 8.962   46.232  36.325 1.00 17.37 ?  153  TRP B H    1 
ATOM   7921  H HA   . TRP B 1 187 ? 6.361   45.894  36.566 1.00 17.17 ?  153  TRP B HA   1 
ATOM   7922  H HB2  . TRP B 1 187 ? 7.976   44.267  37.182 1.00 16.67 ?  153  TRP B HB2  1 
ATOM   7923  H HB3  . TRP B 1 187 ? 8.302   45.149  38.463 1.00 16.67 ?  153  TRP B HB3  1 
ATOM   7924  H HD1  . TRP B 1 187 ? 5.805   42.750  37.315 1.00 15.69 ?  153  TRP B HD1  1 
ATOM   7925  H HE1  . TRP B 1 187 ? 4.297   42.139  39.097 1.00 15.69 ?  153  TRP B HE1  1 
ATOM   7926  H HE3  . TRP B 1 187 ? 7.196   45.993  40.712 1.00 15.83 ?  153  TRP B HE3  1 
ATOM   7927  H HZ2  . TRP B 1 187 ? 3.759   42.966  41.685 1.00 16.33 ?  153  TRP B HZ2  1 
ATOM   7928  H HZ3  . TRP B 1 187 ? 6.215   45.972  42.806 1.00 16.56 ?  153  TRP B HZ3  1 
ATOM   7929  H HH2  . TRP B 1 187 ? 4.492   44.467  43.286 1.00 16.87 ?  153  TRP B HH2  1 
ATOM   7930  N N    . LEU B 1 188 ? 7.678   47.857  38.718 1.00 14.19 ?  154  LEU B N    1 
ATOM   7931  C CA   . LEU B 1 188 ? 7.364   48.924  39.661 1.00 14.07 ?  154  LEU B CA   1 
ATOM   7932  C C    . LEU B 1 188 ? 6.622   50.061  38.987 1.00 15.61 ?  154  LEU B C    1 
ATOM   7933  O O    . LEU B 1 188 ? 5.638   50.559  39.535 1.00 14.38 ?  154  LEU B O    1 
ATOM   7934  C CB   . LEU B 1 188 ? 8.654   49.430  40.305 1.00 14.31 ?  154  LEU B CB   1 
ATOM   7935  C CG   . LEU B 1 188 ? 9.295   48.494  41.318 1.00 15.40 ?  154  LEU B CG   1 
ATOM   7936  C CD1  . LEU B 1 188 ? 10.723  48.946  41.584 1.00 15.44 ?  154  LEU B CD1  1 
ATOM   7937  C CD2  . LEU B 1 188 ? 8.490   48.417  42.602 1.00 15.79 ?  154  LEU B CD2  1 
ATOM   7938  H H    . LEU B 1 188 ? 8.516   47.675  38.649 1.00 17.03 ?  154  LEU B H    1 
ATOM   7939  H HA   . LEU B 1 188 ? 6.789   48.572  40.358 1.00 16.89 ?  154  LEU B HA   1 
ATOM   7940  H HB2  . LEU B 1 188 ? 9.304   49.584  39.603 1.00 17.18 ?  154  LEU B HB2  1 
ATOM   7941  H HB3  . LEU B 1 188 ? 8.458   50.262  40.764 1.00 17.18 ?  154  LEU B HB3  1 
ATOM   7942  H HG   . LEU B 1 188 ? 9.312   47.594  40.956 1.00 18.48 ?  154  LEU B HG   1 
ATOM   7943  H HD11 . LEU B 1 188 ? 10.779  49.298  42.486 1.00 18.53 ?  154  LEU B HD11 1 
ATOM   7944  H HD12 . LEU B 1 188 ? 11.318  48.186  41.487 1.00 18.53 ?  154  LEU B HD12 1 
ATOM   7945  H HD13 . LEU B 1 188 ? 10.960  49.636  40.944 1.00 18.53 ?  154  LEU B HD13 1 
ATOM   7946  H HD21 . LEU B 1 188 ? 8.965   47.860  43.239 1.00 18.94 ?  154  LEU B HD21 1 
ATOM   7947  H HD22 . LEU B 1 188 ? 8.382   49.312  42.961 1.00 18.94 ?  154  LEU B HD22 1 
ATOM   7948  H HD23 . LEU B 1 188 ? 7.622   48.032  42.408 1.00 18.94 ?  154  LEU B HD23 1 
ATOM   7949  N N    . LYS B 1 189 ? 7.057   50.478  37.798 1.00 16.02 ?  155  LYS B N    1 
ATOM   7950  C CA   . LYS B 1 189 ? 6.380   51.572  37.124 1.00 16.65 ?  155  LYS B CA   1 
ATOM   7951  C C    . LYS B 1 189 ? 4.976   51.170  36.720 1.00 16.29 ?  155  LYS B C    1 
ATOM   7952  O O    . LYS B 1 189 ? 4.041   51.979  36.762 1.00 16.00 ?  155  LYS B O    1 
ATOM   7953  C CB   . LYS B 1 189 ? 7.204   51.996  35.901 1.00 17.75 ?  155  LYS B CB   1 
ATOM   7954  C CG   . LYS B 1 189 ? 6.653   53.209  35.187 1.00 23.31 ?  155  LYS B CG   1 
ATOM   7955  C CD   . LYS B 1 189 ? 7.644   53.707  34.121 1.00 26.05 ?  155  LYS B CD   1 
ATOM   7956  C CE   . LYS B 1 189 ? 6.951   54.035  32.811 1.00 34.64 ?  155  LYS B CE   1 
ATOM   7957  N NZ   . LYS B 1 189 ? 5.957   55.106  33.002 1.00 27.81 ?  155  LYS B NZ   1 
ATOM   7958  H H    . LYS B 1 189 ? 7.728   50.148  37.372 1.00 19.22 ?  155  LYS B H    1 
ATOM   7959  H HA   . LYS B 1 189 ? 6.309   52.334  37.721 1.00 19.97 ?  155  LYS B HA   1 
ATOM   7960  H HB2  . LYS B 1 189 ? 8.105   52.207  36.190 1.00 21.30 ?  155  LYS B HB2  1 
ATOM   7961  H HB3  . LYS B 1 189 ? 7.222   51.262  35.267 1.00 21.30 ?  155  LYS B HB3  1 
ATOM   7962  H HG2  . LYS B 1 189 ? 5.819   52.976  34.749 1.00 27.97 ?  155  LYS B HG2  1 
ATOM   7963  H HG3  . LYS B 1 189 ? 6.504   53.922  35.827 1.00 27.97 ?  155  LYS B HG3  1 
ATOM   7964  H HD2  . LYS B 1 189 ? 8.081   54.512  34.442 1.00 31.26 ?  155  LYS B HD2  1 
ATOM   7965  H HD3  . LYS B 1 189 ? 8.304   53.017  33.950 1.00 31.26 ?  155  LYS B HD3  1 
ATOM   7966  H HE2  . LYS B 1 189 ? 7.608   54.335  32.163 1.00 41.57 ?  155  LYS B HE2  1 
ATOM   7967  H HE3  . LYS B 1 189 ? 6.495   53.246  32.479 1.00 41.57 ?  155  LYS B HE3  1 
ATOM   7968  H HZ1  . LYS B 1 189 ? 5.299   54.819  33.528 1.00 33.37 ?  155  LYS B HZ1  1 
ATOM   7969  H HZ2  . LYS B 1 189 ? 6.341   55.814  33.380 1.00 33.37 ?  155  LYS B HZ2  1 
ATOM   7970  H HZ3  . LYS B 1 189 ? 5.615   55.347  32.216 1.00 33.37 ?  155  LYS B HZ3  1 
ATOM   7971  N N    . SER B 1 190 ? 4.780   49.912  36.321 1.00 14.55 ?  156  SER B N    1 
ATOM   7972  C CA   . SER B 1 190 ? 3.443   49.494  35.949 1.00 12.63 ?  156  SER B CA   1 
ATOM   7973  C C    . SER B 1 190 ? 2.483   49.616  37.135 1.00 14.52 ?  156  SER B C    1 
ATOM   7974  O O    . SER B 1 190 ? 1.330   50.051  36.969 1.00 14.96 ?  156  SER B O    1 
ATOM   7975  C CB   . SER B 1 190 ? 3.461   48.056  35.384 1.00 14.12 ?  156  SER B CB   1 
ATOM   7976  O OG   . SER B 1 190 ? 3.586   47.025  36.382 1.00 14.35 ?  156  SER B OG   1 
ATOM   7977  H H    . SER B 1 190 ? 5.387   49.306  36.261 1.00 17.46 ?  156  SER B H    1 
ATOM   7978  H HA   . SER B 1 190 ? 3.117   50.072  35.241 1.00 15.15 ?  156  SER B HA   1 
ATOM   7979  H HB2  . SER B 1 190 ? 2.630   47.911  34.904 1.00 16.94 ?  156  SER B HB2  1 
ATOM   7980  H HB3  . SER B 1 190 ? 4.213   47.981  34.776 1.00 16.94 ?  156  SER B HB3  1 
ATOM   7981  H HG   . SER B 1 190 ? 4.237   47.192  36.886 1.00 17.22 ?  156  SER B HG   1 
ATOM   7982  N N    . VAL B 1 191 ? 2.953   49.281  38.337 1.00 13.67 ?  157  VAL B N    1 
ATOM   7983  C CA   . VAL B 1 191 ? 2.115   49.392  39.531 1.00 13.00 ?  157  VAL B CA   1 
ATOM   7984  C C    . VAL B 1 191 ? 1.883   50.857  39.885 1.00 13.98 ?  157  VAL B C    1 
ATOM   7985  O O    . VAL B 1 191 ? 0.754   51.289  40.140 1.00 14.50 ?  157  VAL B O    1 
ATOM   7986  C CB   . VAL B 1 191 ? 2.737   48.617  40.707 1.00 12.98 ?  157  VAL B CB   1 
ATOM   7987  C CG1  . VAL B 1 191 ? 1.952   48.866  41.952 1.00 14.13 ?  157  VAL B CG1  1 
ATOM   7988  C CG2  . VAL B 1 191 ? 2.756   47.119  40.389 1.00 13.97 ?  157  VAL B CG2  1 
ATOM   7989  H H    . VAL B 1 191 ? 3.748   48.988  38.488 1.00 16.40 ?  157  VAL B H    1 
ATOM   7990  H HA   . VAL B 1 191 ? 1.253   48.992  39.336 1.00 15.60 ?  157  VAL B HA   1 
ATOM   7991  H HB   . VAL B 1 191 ? 3.648   48.919  40.848 1.00 15.57 ?  157  VAL B HB   1 
ATOM   7992  H HG11 . VAL B 1 191 ? 2.243   48.246  42.638 1.00 16.96 ?  157  VAL B HG11 1 
ATOM   7993  H HG12 . VAL B 1 191 ? 2.105   49.778  42.244 1.00 16.96 ?  157  VAL B HG12 1 
ATOM   7994  H HG13 . VAL B 1 191 ? 1.010   48.733  41.763 1.00 16.96 ?  157  VAL B HG13 1 
ATOM   7995  H HG21 . VAL B 1 191 ? 3.196   46.648  41.113 1.00 16.76 ?  157  VAL B HG21 1 
ATOM   7996  H HG22 . VAL B 1 191 ? 1.843   46.804  40.296 1.00 16.76 ?  157  VAL B HG22 1 
ATOM   7997  H HG23 . VAL B 1 191 ? 3.240   46.978  39.560 1.00 16.76 ?  157  VAL B HG23 1 
ATOM   7998  N N    . GLU B 1 192 ? 2.969   51.621  39.936 1.00 13.43 ?  158  GLU B N    1 
ATOM   7999  C CA   . GLU B 1 192 ? 2.880   53.021  40.330 1.00 14.08 ?  158  GLU B CA   1 
ATOM   8000  C C    . GLU B 1 192 ? 2.021   53.811  39.354 1.00 15.22 ?  158  GLU B C    1 
ATOM   8001  O O    . GLU B 1 192 ? 1.222   54.672  39.775 1.00 15.26 ?  158  GLU B O    1 
ATOM   8002  C CB   . GLU B 1 192 ? 4.295   53.584  40.439 1.00 15.01 ?  158  GLU B CB   1 
ATOM   8003  C CG   . GLU B 1 192 ? 5.070   53.025  41.631 1.00 15.40 ?  158  GLU B CG   1 
ATOM   8004  C CD   . GLU B 1 192 ? 6.576   53.247  41.576 1.00 17.63 ?  158  GLU B CD   1 
ATOM   8005  O OE1  . GLU B 1 192 ? 7.096   53.736  40.571 1.00 21.73 ?  158  GLU B OE1  1 
ATOM   8006  O OE2  . GLU B 1 192 ? 7.244   52.865  42.557 1.00 21.25 ?  158  GLU B OE2  1 
ATOM   8007  H H    . GLU B 1 192 ? 3.765   51.355  39.748 1.00 16.11 ?  158  GLU B H    1 
ATOM   8008  H HA   . GLU B 1 192 ? 2.456   53.105  41.198 1.00 16.90 ?  158  GLU B HA   1 
ATOM   8009  H HB2  . GLU B 1 192 ? 4.785   53.360  39.632 1.00 18.02 ?  158  GLU B HB2  1 
ATOM   8010  H HB3  . GLU B 1 192 ? 4.244   54.547  40.540 1.00 18.02 ?  158  GLU B HB3  1 
ATOM   8011  H HG2  . GLU B 1 192 ? 4.742   53.451  42.439 1.00 18.48 ?  158  GLU B HG2  1 
ATOM   8012  H HG3  . GLU B 1 192 ? 4.918   52.068  41.676 1.00 18.48 ?  158  GLU B HG3  1 
ATOM   8013  N N    . ASP B 1 193 ? 2.193   53.581  38.049 1.00 13.46 ?  159  ASP B N    1 
ATOM   8014  C CA   . ASP B 1 193 ? 1.383   54.272  37.052 1.00 15.65 ?  159  ASP B CA   1 
ATOM   8015  C C    . ASP B 1 193 ? -0.098  53.958  37.234 1.00 14.87 ?  159  ASP B C    1 
ATOM   8016  O O    . ASP B 1 193 ? -0.956  54.845  37.135 1.00 16.26 ?  159  ASP B O    1 
ATOM   8017  C CB   . ASP B 1 193 ? 1.800   53.915  35.622 1.00 15.78 ?  159  ASP B CB   1 
ATOM   8018  C CG   . ASP B 1 193 ? 3.082   54.588  35.185 1.00 16.56 ?  159  ASP B CG   1 
ATOM   8019  O OD1  . ASP B 1 193 ? 3.601   55.444  35.912 1.00 19.51 ?  159  ASP B OD1  1 
ATOM   8020  O OD2  . ASP B 1 193 ? 3.537   54.219  34.087 1.00 20.96 ?  159  ASP B OD2  1 
ATOM   8021  H H    . ASP B 1 193 ? 2.769   53.033  37.719 1.00 16.15 ?  159  ASP B H    1 
ATOM   8022  H HA   . ASP B 1 193 ? 1.536   55.222  37.173 1.00 18.78 ?  159  ASP B HA   1 
ATOM   8023  H HB2  . ASP B 1 193 ? 1.933   52.956  35.564 1.00 18.94 ?  159  ASP B HB2  1 
ATOM   8024  H HB3  . ASP B 1 193 ? 1.098   54.191  35.013 1.00 18.94 ?  159  ASP B HB3  1 
ATOM   8025  N N    . MET B 1 194 ? -0.449  52.690  37.506 1.00 13.10 ?  160  MET B N    1 
ATOM   8026  C CA   . MET B 1 194 ? -1.871  52.388  37.588 1.00 13.77 ?  160  MET B CA   1 
ATOM   8027  C C    . MET B 1 194 ? -2.434  52.942  38.906 1.00 13.07 ?  160  MET B C    1 
ATOM   8028  O O    . MET B 1 194 ? -3.544  53.494  38.935 1.00 13.60 ?  160  MET B O    1 
ATOM   8029  C CB   . MET B 1 194 ? -2.152  50.865  37.377 1.00 13.94 ?  160  MET B CB   1 
ATOM   8030  C CG   . MET B 1 194 ? -3.559  50.514  37.753 1.00 13.26 ?  160  MET B CG   1 
ATOM   8031  S SD   . MET B 1 194 ? -4.608  51.043  36.231 1.00 14.68 ?  160  MET B SD   1 
ATOM   8032  C CE   . MET B 1 194 ? -4.284  49.737  35.099 1.00 19.00 ?  160  MET B CE   1 
ATOM   8033  H H    . MET B 1 194 ? 0.090   52.033  37.638 1.00 15.72 ?  160  MET B H    1 
ATOM   8034  H HA   . MET B 1 194 ? -2.343  52.806  36.851 1.00 16.52 ?  160  MET B HA   1 
ATOM   8035  H HB2  . MET B 1 194 ? -2.019  50.640  36.443 1.00 16.73 ?  160  MET B HB2  1 
ATOM   8036  H HB3  . MET B 1 194 ? -1.548  50.347  37.932 1.00 16.73 ?  160  MET B HB3  1 
ATOM   8037  H HG2  . MET B 1 194 ? -3.649  49.561  37.906 1.00 15.91 ?  160  MET B HG2  1 
ATOM   8038  H HG3  . MET B 1 194 ? -3.841  51.005  38.540 1.00 15.91 ?  160  MET B HG3  1 
ATOM   8039  H HE1  . MET B 1 194 ? -4.797  49.887  34.290 1.00 22.80 ?  160  MET B HE1  1 
ATOM   8040  H HE2  . MET B 1 194 ? -3.336  49.726  34.893 1.00 22.80 ?  160  MET B HE2  1 
ATOM   8041  H HE3  . MET B 1 194 ? -4.544  48.896  35.506 1.00 22.80 ?  160  MET B HE3  1 
ATOM   8042  N N    . VAL B 1 195 ? -1.673  52.873  40.000 1.00 14.27 ?  161  VAL B N    1 
ATOM   8043  C CA   . VAL B 1 195 ? -2.158  53.407  41.263 1.00 13.51 ?  161  VAL B CA   1 
ATOM   8044  C C    . VAL B 1 195 ? -2.279  54.932  41.204 1.00 14.60 ?  161  VAL B C    1 
ATOM   8045  O O    . VAL B 1 195 ? -3.138  55.503  41.869 1.00 14.94 ?  161  VAL B O    1 
ATOM   8046  C CB   . VAL B 1 195 ? -1.284  52.929  42.434 1.00 12.64 ?  161  VAL B CB   1 
ATOM   8047  C CG1  . VAL B 1 195 ? -1.691  53.588  43.732 1.00 14.55 ?  161  VAL B CG1  1 
ATOM   8048  C CG2  . VAL B 1 195 ? -1.374  51.411  42.574 1.00 13.67 ?  161  VAL B CG2  1 
ATOM   8049  H H    . VAL B 1 195 ? -0.886  52.527  40.033 1.00 17.12 ?  161  VAL B H    1 
ATOM   8050  H HA   . VAL B 1 195 ? -3.049  53.056  41.416 1.00 16.22 ?  161  VAL B HA   1 
ATOM   8051  H HB   . VAL B 1 195 ? -0.366  53.179  42.247 1.00 15.17 ?  161  VAL B HB   1 
ATOM   8052  H HG11 . VAL B 1 195 ? -1.260  53.127  44.469 1.00 17.46 ?  161  VAL B HG11 1 
ATOM   8053  H HG12 . VAL B 1 195 ? -1.414  54.517  43.715 1.00 17.46 ?  161  VAL B HG12 1 
ATOM   8054  H HG13 . VAL B 1 195 ? -2.655  53.532  43.826 1.00 17.46 ?  161  VAL B HG13 1 
ATOM   8055  H HG21 . VAL B 1 195 ? -0.754  51.121  43.261 1.00 16.40 ?  161  VAL B HG21 1 
ATOM   8056  H HG22 . VAL B 1 195 ? -2.280  51.170  42.823 1.00 16.40 ?  161  VAL B HG22 1 
ATOM   8057  H HG23 . VAL B 1 195 ? -1.144  51.002  41.726 1.00 16.40 ?  161  VAL B HG23 1 
ATOM   8058  N N    . ALA B 1 196 ? -1.487  55.611  40.361 1.00 13.67 ?  162  ALA B N    1 
ATOM   8059  C CA   . ALA B 1 196 ? -1.583  57.069  40.262 1.00 14.57 ?  162  ALA B CA   1 
ATOM   8060  C C    . ALA B 1 196 ? -2.845  57.523  39.551 1.00 14.85 ?  162  ALA B C    1 
ATOM   8061  O O    . ALA B 1 196 ? -3.174  58.730  39.625 1.00 16.95 ?  162  ALA B O    1 
ATOM   8062  C CB   . ALA B 1 196 ? -0.338  57.594  39.547 1.00 14.69 ?  162  ALA B CB   1 
ATOM   8063  H H    . ALA B 1 196 ? -0.897  55.254  39.847 1.00 16.41 ?  162  ALA B H    1 
ATOM   8064  H HA   . ALA B 1 196 ? -1.613  57.457  41.150 1.00 17.48 ?  162  ALA B HA   1 
ATOM   8065  H HB1  . ALA B 1 196 ? -0.400  58.559  39.473 1.00 17.63 ?  162  ALA B HB1  1 
ATOM   8066  H HB2  . ALA B 1 196 ? 0.447   57.351  40.062 1.00 17.63 ?  162  ALA B HB2  1 
ATOM   8067  H HB3  . ALA B 1 196 ? -0.290  57.197  38.664 1.00 17.63 ?  162  ALA B HB3  1 
ATOM   8068  N N    . THR B 1 197 ? -3.552  56.659  38.834 1.00 14.19 ?  163  THR B N    1 
ATOM   8069  C CA   . THR B 1 197 ? -4.784  57.054  38.163 1.00 15.06 ?  163  THR B CA   1 
ATOM   8070  C C    . THR B 1 197 ? -5.858  57.365  39.189 1.00 14.99 ?  163  THR B C    1 
ATOM   8071  O O    . THR B 1 197 ? -5.788  56.943  40.331 1.00 13.67 ?  163  THR B O    1 
ATOM   8072  C CB   . THR B 1 197 ? -5.226  56.023  37.139 1.00 13.74 ?  163  THR B CB   1 
ATOM   8073  O OG1  . THR B 1 197 ? -5.683  54.826  37.811 1.00 13.75 ?  163  THR B OG1  1 
ATOM   8074  C CG2  . THR B 1 197 ? -4.098  55.734  36.166 1.00 14.30 ?  163  THR B CG2  1 
ATOM   8075  H H    . THR B 1 197 ? -3.340  55.834  38.719 1.00 17.02 ?  163  THR B H    1 
ATOM   8076  H HA   . THR B 1 197 ? -4.635  57.864  37.651 1.00 18.07 ?  163  THR B HA   1 
ATOM   8077  H HB   . THR B 1 197 ? -5.969  56.362  36.615 1.00 16.49 ?  163  THR B HB   1 
ATOM   8078  H HG1  . THR B 1 197 ? -5.188  54.659  38.469 1.00 16.49 ?  163  THR B HG1  1 
ATOM   8079  H HG21 . THR B 1 197 ? -4.377  55.063  35.524 1.00 17.16 ?  163  THR B HG21 1 
ATOM   8080  H HG22 . THR B 1 197 ? -3.854  56.544  35.690 1.00 17.16 ?  163  THR B HG22 1 
ATOM   8081  H HG23 . THR B 1 197 ? -3.321  55.406  36.647 1.00 17.16 ?  163  THR B HG23 1 
ATOM   8082  N N    . PRO B 1 198 ? -6.852  58.181  38.836 1.00 14.52 ?  164  PRO B N    1 
ATOM   8083  C CA   . PRO B 1 198 ? -7.637  58.801  39.890 1.00 13.92 ?  164  PRO B CA   1 
ATOM   8084  C C    . PRO B 1 198 ? -8.585  57.875  40.613 1.00 15.04 ?  164  PRO B C    1 
ATOM   8085  O O    . PRO B 1 198 ? -8.960  58.174  41.753 1.00 17.76 ?  164  PRO B O    1 
ATOM   8086  C CB   . PRO B 1 198 ? -8.405  59.924  39.144 1.00 14.01 ?  164  PRO B CB   1 
ATOM   8087  C CG   . PRO B 1 198 ? -8.367  59.503  37.700 1.00 15.02 ?  164  PRO B CG   1 
ATOM   8088  C CD   . PRO B 1 198 ? -7.043  58.837  37.528 1.00 14.82 ?  164  PRO B CD   1 
ATOM   8089  H HA   . PRO B 1 198 ? -7.032  59.186  40.543 1.00 16.70 ?  164  PRO B HA   1 
ATOM   8090  H HB2  . PRO B 1 198 ? -9.318  59.976  39.469 1.00 16.81 ?  164  PRO B HB2  1 
ATOM   8091  H HB3  . PRO B 1 198 ? -7.958  60.775  39.273 1.00 16.81 ?  164  PRO B HB3  1 
ATOM   8092  H HG2  . PRO B 1 198 ? -9.092  58.886  37.515 1.00 18.02 ?  164  PRO B HG2  1 
ATOM   8093  H HG3  . PRO B 1 198 ? -8.440  60.282  37.126 1.00 18.02 ?  164  PRO B HG3  1 
ATOM   8094  H HD2  . PRO B 1 198 ? -7.071  58.185  36.810 1.00 17.78 ?  164  PRO B HD2  1 
ATOM   8095  H HD3  . PRO B 1 198 ? -6.344  59.488  37.358 1.00 17.78 ?  164  PRO B HD3  1 
ATOM   8096  N N    . ASN B 1 199 ? -9.024  56.784  39.984 1.00 13.68 ?  165  ASN B N    1 
ATOM   8097  C CA   . ASN B 1 199 ? -10.043 55.914  40.537 1.00 13.29 ?  165  ASN B CA   1 
ATOM   8098  C C    . ASN B 1 199 ? -9.491  54.643  41.198 1.00 12.31 ?  165  ASN B C    1 
ATOM   8099  O O    . ASN B 1 199 ? -10.286 53.785  41.612 1.00 13.63 ?  165  ASN B O    1 
ATOM   8100  C CB   . ASN B 1 199 ? -11.089 55.586  39.487 1.00 12.84 ?  165  ASN B CB   1 
ATOM   8101  C CG   . ASN B 1 199 ? -11.713 56.832  38.903 1.00 14.60 ?  165  ASN B CG   1 
ATOM   8102  O OD1  . ASN B 1 199 ? -12.353 57.580  39.624 1.00 14.72 ?  165  ASN B OD1  1 
ATOM   8103  N ND2  . ASN B 1 199 ? -11.436 57.085  37.616 1.00 15.15 ?  165  ASN B ND2  1 
ATOM   8104  H H    . ASN B 1 199 ? -8.735  56.526  39.217 1.00 16.41 ?  165  ASN B H    1 
ATOM   8105  H HA   . ASN B 1 199 ? -10.494 56.402  41.243 1.00 15.94 ?  165  ASN B HA   1 
ATOM   8106  H HB2  . ASN B 1 199 ? -10.672 55.089  38.766 1.00 15.41 ?  165  ASN B HB2  1 
ATOM   8107  H HB3  . ASN B 1 199 ? -11.792 55.055  39.893 1.00 15.41 ?  165  ASN B HB3  1 
ATOM   8108  H HD21 . ASN B 1 199 ? -10.929 56.550  37.173 1.00 18.18 ?  165  ASN B HD21 1 
ATOM   8109  H HD22 . ASN B 1 199 ? -11.765 57.781  37.234 1.00 18.18 ?  165  ASN B HD22 1 
ATOM   8110  N N    . ILE B 1 200 ? -8.187  54.558  41.335 1.00 12.01 ?  166  ILE B N    1 
ATOM   8111  C CA   . ILE B 1 200 ? -7.497  53.423  41.954 1.00 13.30 ?  166  ILE B CA   1 
ATOM   8112  C C    . ILE B 1 200 ? -6.809  53.917  43.212 1.00 13.27 ?  166  ILE B C    1 
ATOM   8113  O O    . ILE B 1 200 ? -6.115  54.945  43.202 1.00 13.55 ?  166  ILE B O    1 
ATOM   8114  C CB   . ILE B 1 200 ? -6.482  52.800  40.985 1.00 12.06 ?  166  ILE B CB   1 
ATOM   8115  C CG1  . ILE B 1 200 ? -7.191  52.195  39.776 1.00 15.83 ?  166  ILE B CG1  1 
ATOM   8116  C CG2  . ILE B 1 200 ? -5.636  51.756  41.731 1.00 12.56 ?  166  ILE B CG2  1 
ATOM   8117  C CD1  . ILE B 1 200 ? -7.956  50.975  40.067 1.00 17.63 ?  166  ILE B CD1  1 
ATOM   8118  H H    . ILE B 1 200 ? -7.644  55.169  41.068 1.00 14.41 ?  166  ILE B H    1 
ATOM   8119  H HA   . ILE B 1 200 ? -8.142  52.745  42.207 1.00 15.96 ?  166  ILE B HA   1 
ATOM   8120  H HB   . ILE B 1 200 ? -5.892  53.494  40.651 1.00 14.48 ?  166  ILE B HB   1 
ATOM   8121  H HG12 . ILE B 1 200 ? -7.810  52.851  39.420 1.00 19.00 ?  166  ILE B HG12 1 
ATOM   8122  H HG13 . ILE B 1 200 ? -6.525  51.970  39.108 1.00 19.00 ?  166  ILE B HG13 1 
ATOM   8123  H HG21 . ILE B 1 200 ? -5.080  51.285  41.092 1.00 15.07 ?  166  ILE B HG21 1 
ATOM   8124  H HG22 . ILE B 1 200 ? -5.079  52.209  42.384 1.00 15.07 ?  166  ILE B HG22 1 
ATOM   8125  H HG23 . ILE B 1 200 ? -6.228  51.131  42.179 1.00 15.07 ?  166  ILE B HG23 1 
ATOM   8126  H HD11 . ILE B 1 200 ? -8.394  50.675  39.255 1.00 21.16 ?  166  ILE B HD11 1 
ATOM   8127  H HD12 . ILE B 1 200 ? -7.348  50.290  40.388 1.00 21.16 ?  166  ILE B HD12 1 
ATOM   8128  H HD13 . ILE B 1 200 ? -8.619  51.172  40.747 1.00 21.16 ?  166  ILE B HD13 1 
ATOM   8129  N N    . ASP B 1 201 ? -7.020  53.216  44.314 1.00 12.81 ?  167  ASP B N    1 
ATOM   8130  C CA   . ASP B 1 201 ? -6.476  53.638  45.598 1.00 13.09 ?  167  ASP B CA   1 
ATOM   8131  C C    . ASP B 1 201 ? -5.237  52.890  46.060 1.00 12.42 ?  167  ASP B C    1 
ATOM   8132  O O    . ASP B 1 201 ? -4.556  53.326  46.987 1.00 13.38 ?  167  ASP B O    1 
ATOM   8133  C CB   . ASP B 1 201 ? -7.564  53.519  46.660 1.00 13.00 ?  167  ASP B CB   1 
ATOM   8134  C CG   . ASP B 1 201 ? -8.780  54.304  46.303 1.00 13.53 ?  167  ASP B CG   1 
ATOM   8135  O OD1  . ASP B 1 201 ? -8.637  55.570  46.271 1.00 15.11 ?  167  ASP B OD1  1 
ATOM   8136  O OD2  . ASP B 1 201 ? -9.840  53.747  46.028 1.00 13.30 ?  167  ASP B OD2  1 
ATOM   8137  H H    . ASP B 1 201 ? -7.477  52.488  44.346 1.00 15.37 ?  167  ASP B H    1 
ATOM   8138  H HA   . ASP B 1 201 ? -6.203  54.565  45.515 1.00 15.71 ?  167  ASP B HA   1 
ATOM   8139  H HB2  . ASP B 1 201 ? -7.820  52.588  46.752 1.00 15.60 ?  167  ASP B HB2  1 
ATOM   8140  H HB3  . ASP B 1 201 ? -7.223  53.854  47.504 1.00 15.60 ?  167  ASP B HB3  1 
ATOM   8141  N N    . GLY B 1 202 ? -4.895  51.782  45.417 1.00 12.83 ?  168  GLY B N    1 
ATOM   8142  C CA   . GLY B 1 202 ? -3.776  50.989  45.885 1.00 11.39 ?  168  GLY B CA   1 
ATOM   8143  C C    . GLY B 1 202 ? -3.651  49.751  45.051 1.00 11.66 ?  168  GLY B C    1 
ATOM   8144  O O    . GLY B 1 202 ? -4.263  49.600  43.992 1.00 12.69 ?  168  GLY B O    1 
ATOM   8145  H H    . GLY B 1 202 ? -5.290  51.475  44.718 1.00 15.40 ?  168  GLY B H    1 
ATOM   8146  H HA2  . GLY B 1 202 ? -2.955  51.501  45.817 1.00 13.66 ?  168  GLY B HA2  1 
ATOM   8147  H HA3  . GLY B 1 202 ? -3.914  50.734  46.811 1.00 13.66 ?  168  GLY B HA3  1 
ATOM   8148  N N    . THR B 1 203 ? -2.861  48.834  45.589 1.00 11.75 ?  169  THR B N    1 
ATOM   8149  C CA   . THR B 1 203 ? -2.522  47.606  44.899 1.00 11.67 ?  169  THR B CA   1 
ATOM   8150  C C    . THR B 1 203 ? -2.591  46.419  45.845 1.00 11.91 ?  169  THR B C    1 
ATOM   8151  O O    . THR B 1 203 ? -2.398  46.536  47.056 1.00 11.70 ?  169  THR B O    1 
ATOM   8152  C CB   . THR B 1 203 ? -1.130  47.738  44.247 1.00 11.39 ?  169  THR B CB   1 
ATOM   8153  O OG1  . THR B 1 203 ? -0.888  46.633  43.375 1.00 11.94 ?  169  THR B OG1  1 
ATOM   8154  C CG2  . THR B 1 203 ? -0.040  47.830  45.236 1.00 13.51 ?  169  THR B CG2  1 
ATOM   8155  H H    . THR B 1 203 ? -2.502  48.904  46.367 1.00 14.10 ?  169  THR B H    1 
ATOM   8156  H HA   . THR B 1 203 ? -3.175  47.418  44.206 1.00 14.00 ?  169  THR B HA   1 
ATOM   8157  H HB   . THR B 1 203 ? -1.122  48.564  43.740 1.00 13.67 ?  169  THR B HB   1 
ATOM   8158  H HG1  . THR B 1 203 ? -1.520  46.556  42.826 1.00 14.33 ?  169  THR B HG1  1 
ATOM   8159  H HG21 . THR B 1 203 ? 0.786   48.083  44.796 1.00 16.21 ?  169  THR B HG21 1 
ATOM   8160  H HG22 . THR B 1 203 ? -0.257  48.497  45.907 1.00 16.21 ?  169  THR B HG22 1 
ATOM   8161  H HG23 . THR B 1 203 ? 0.085   46.973  45.673 1.00 16.21 ?  169  THR B HG23 1 
ATOM   8162  N N    . PHE B 1 204 ? -2.886  45.247  45.242 1.00 11.08 ?  170  PHE B N    1 
ATOM   8163  C CA   . PHE B 1 204 ? -2.885  43.945  45.891 1.00 11.01 ?  170  PHE B CA   1 
ATOM   8164  C C    . PHE B 1 204 ? -1.690  43.226  45.303 1.00 10.53 ?  170  PHE B C    1 
ATOM   8165  O O    . PHE B 1 204 ? -1.718  42.901  44.111 1.00 11.65 ?  170  PHE B O    1 
ATOM   8166  C CB   . PHE B 1 204 ? -4.185  43.231  45.527 1.00 11.39 ?  170  PHE B CB   1 
ATOM   8167  C CG   . PHE B 1 204 ? -4.303  41.837  46.100 1.00 12.05 ?  170  PHE B CG   1 
ATOM   8168  C CD1  . PHE B 1 204 ? -3.611  40.743  45.578 1.00 13.17 ?  170  PHE B CD1  1 
ATOM   8169  C CD2  . PHE B 1 204 ? -5.197  41.623  47.096 1.00 12.87 ?  170  PHE B CD2  1 
ATOM   8170  C CE1  . PHE B 1 204 ? -3.787  39.441  46.115 1.00 12.64 ?  170  PHE B CE1  1 
ATOM   8171  C CE2  . PHE B 1 204 ? -5.381  40.347  47.642 1.00 12.97 ?  170  PHE B CE2  1 
ATOM   8172  C CZ   . PHE B 1 204 ? -4.650  39.261  47.149 1.00 13.10 ?  170  PHE B CZ   1 
ATOM   8173  H H    . PHE B 1 204 ? -3.100  45.193  44.411 1.00 13.29 ?  170  PHE B H    1 
ATOM   8174  H HA   . PHE B 1 204 ? -2.807  43.993  46.857 1.00 13.22 ?  170  PHE B HA   1 
ATOM   8175  H HB2  . PHE B 1 204 ? -4.931  43.752  45.864 1.00 13.67 ?  170  PHE B HB2  1 
ATOM   8176  H HB3  . PHE B 1 204 ? -4.240  43.159  44.562 1.00 13.67 ?  170  PHE B HB3  1 
ATOM   8177  H HD1  . PHE B 1 204 ? -3.025  40.869  44.867 1.00 15.80 ?  170  PHE B HD1  1 
ATOM   8178  H HD2  . PHE B 1 204 ? -5.696  42.337  47.423 1.00 15.45 ?  170  PHE B HD2  1 
ATOM   8179  H HE1  . PHE B 1 204 ? -3.316  38.720  45.763 1.00 15.17 ?  170  PHE B HE1  1 
ATOM   8180  H HE2  . PHE B 1 204 ? -5.990  40.221  48.334 1.00 15.56 ?  170  PHE B HE2  1 
ATOM   8181  H HZ   . PHE B 1 204 ? -4.755  38.418  47.528 1.00 15.72 ?  170  PHE B HZ   1 
ATOM   8182  N N    . ILE B 1 205 ? -0.655  42.975  46.105 1.00 11.79 ?  171  ILE B N    1 
ATOM   8183  C CA   . ILE B 1 205 ? 0.550   42.295  45.629 1.00 11.20 ?  171  ILE B CA   1 
ATOM   8184  C C    . ILE B 1 205 ? 0.437   40.806  45.914 1.00 11.06 ?  171  ILE B C    1 
ATOM   8185  O O    . ILE B 1 205 ? 0.294   40.402  47.069 1.00 11.79 ?  171  ILE B O    1 
ATOM   8186  C CB   . ILE B 1 205 ? 1.817   42.872  46.261 1.00 12.16 ?  171  ILE B CB   1 
ATOM   8187  C CG1  . ILE B 1 205 ? 1.924   44.374  45.980 1.00 12.24 ?  171  ILE B CG1  1 
ATOM   8188  C CG2  . ILE B 1 205 ? 3.028   42.156  45.735 1.00 12.99 ?  171  ILE B CG2  1 
ATOM   8189  C CD1  . ILE B 1 205 ? 1.846   44.747  44.505 1.00 14.40 ?  171  ILE B CD1  1 
ATOM   8190  H H    . ILE B 1 205 ? -0.627  43.192  46.937 1.00 14.15 ?  171  ILE B H    1 
ATOM   8191  H HA   . ILE B 1 205 ? 0.602   42.416  44.668 1.00 13.45 ?  171  ILE B HA   1 
ATOM   8192  H HB   . ILE B 1 205 ? 1.765   42.743  47.221 1.00 14.59 ?  171  ILE B HB   1 
ATOM   8193  H HG12 . ILE B 1 205 ? 1.197   44.826  46.435 1.00 14.69 ?  171  ILE B HG12 1 
ATOM   8194  H HG13 . ILE B 1 205 ? 2.776   44.691  46.317 1.00 14.69 ?  171  ILE B HG13 1 
ATOM   8195  H HG21 . ILE B 1 205 ? 3.824   42.574  46.098 1.00 15.59 ?  171  ILE B HG21 1 
ATOM   8196  H HG22 . ILE B 1 205 ? 2.989   41.226  46.008 1.00 15.59 ?  171  ILE B HG22 1 
ATOM   8197  H HG23 . ILE B 1 205 ? 3.034   42.217  44.767 1.00 15.59 ?  171  ILE B HG23 1 
ATOM   8198  H HD11 . ILE B 1 205 ? 2.094   45.679  44.401 1.00 17.28 ?  171  ILE B HD11 1 
ATOM   8199  H HD12 . ILE B 1 205 ? 2.457   44.184  44.004 1.00 17.28 ?  171  ILE B HD12 1 
ATOM   8200  H HD13 . ILE B 1 205 ? 0.938   44.609  44.192 1.00 17.28 ?  171  ILE B HD13 1 
ATOM   8201  N N    . ASP B 1 206 ? 0.477   39.996  44.856 1.00 11.02 ?  172  ASP B N    1 
ATOM   8202  C CA   . ASP B 1 206 ? 0.311   38.556  44.953 1.00 11.75 ?  172  ASP B CA   1 
ATOM   8203  C C    . ASP B 1 206 ? 1.643   37.874  44.664 1.00 10.17 ?  172  ASP B C    1 
ATOM   8204  O O    . ASP B 1 206 ? 2.521   38.390  43.983 1.00 11.22 ?  172  ASP B O    1 
ATOM   8205  C CB   . ASP B 1 206 ? -0.784  38.088  43.983 1.00 11.20 ?  172  ASP B CB   1 
ATOM   8206  C CG   . ASP B 1 206 ? -1.194  36.659  44.202 1.00 11.07 ?  172  ASP B CG   1 
ATOM   8207  O OD1  . ASP B 1 206 ? -1.078  36.191  45.360 1.00 12.51 ?  172  ASP B OD1  1 
ATOM   8208  O OD2  . ASP B 1 206 ? -1.634  36.017  43.228 1.00 12.23 ?  172  ASP B OD2  1 
ATOM   8209  H H    . ASP B 1 206 ? 0.603   40.270  44.051 1.00 13.23 ?  172  ASP B H    1 
ATOM   8210  H HA   . ASP B 1 206 ? 0.040   38.295  45.847 1.00 14.10 ?  172  ASP B HA   1 
ATOM   8211  H HB2  . ASP B 1 206 ? -1.569  38.645  44.102 1.00 13.44 ?  172  ASP B HB2  1 
ATOM   8212  H HB3  . ASP B 1 206 ? -0.455  38.169  43.074 1.00 13.44 ?  172  ASP B HB3  1 
ATOM   8213  N N    . ALA B 1 207 ? 1.729   36.645  45.184 1.00 11.76 ?  173  ALA B N    1 
ATOM   8214  C CA   . ALA B 1 207 ? 2.815   35.661  44.953 1.00 11.91 ?  173  ALA B CA   1 
ATOM   8215  C C    . ALA B 1 207 ? 4.071   35.914  45.776 1.00 10.94 ?  173  ALA B C    1 
ATOM   8216  O O    . ALA B 1 207 ? 5.146   35.294  45.540 1.00 11.48 ?  173  ALA B O    1 
ATOM   8217  C CB   . ALA B 1 207 ? 3.123   35.403  43.481 1.00 12.61 ?  173  ALA B CB   1 
ATOM   8218  H H    . ALA B 1 207 ? 1.129   36.329  45.713 1.00 14.11 ?  173  ALA B H    1 
ATOM   8219  H HA   . ALA B 1 207 ? 2.478   34.811  45.276 1.00 14.29 ?  173  ALA B HA   1 
ATOM   8220  H HB1  . ALA B 1 207 ? 3.803   34.713  43.416 1.00 15.13 ?  173  ALA B HB1  1 
ATOM   8221  H HB2  . ALA B 1 207 ? 2.313   35.111  43.035 1.00 15.13 ?  173  ALA B HB2  1 
ATOM   8222  H HB3  . ALA B 1 207 ? 3.446   36.224  43.077 1.00 15.13 ?  173  ALA B HB3  1 
ATOM   8223  N N    . ASN B 1 208 ? 3.948   36.762  46.798 1.00 12.46 ?  174  ASN B N    1 
ATOM   8224  C CA   . ASN B 1 208 ? 5.021   36.946  47.778 1.00 11.83 ?  174  ASN B CA   1 
ATOM   8225  C C    . ASN B 1 208 ? 5.535   35.603  48.283 1.00 12.60 ?  174  ASN B C    1 
ATOM   8226  O O    . ASN B 1 208 ? 6.753   35.395  48.444 1.00 12.98 ?  174  ASN B O    1 
ATOM   8227  C CB   . ASN B 1 208 ? 4.490   37.740  48.950 1.00 12.48 ?  174  ASN B CB   1 
ATOM   8228  C CG   . ASN B 1 208 ? 3.727   38.970  48.492 1.00 11.49 ?  174  ASN B CG   1 
ATOM   8229  O OD1  . ASN B 1 208 ? 4.323   40.009  48.131 1.00 13.52 ?  174  ASN B OD1  1 
ATOM   8230  N ND2  . ASN B 1 208 ? 2.414   38.850  48.445 1.00 12.58 ?  174  ASN B ND2  1 
ATOM   8231  H H    . ASN B 1 208 ? 3.253   37.244  46.949 1.00 14.96 ?  174  ASN B H    1 
ATOM   8232  H HA   . ASN B 1 208 ? 5.753   37.428  47.362 1.00 14.20 ?  174  ASN B HA   1 
ATOM   8233  H HB2  . ASN B 1 208 ? 3.887   37.183  49.467 1.00 14.97 ?  174  ASN B HB2  1 
ATOM   8234  H HB3  . ASN B 1 208 ? 5.231   38.029  49.503 1.00 14.97 ?  174  ASN B HB3  1 
ATOM   8235  H HD21 . ASN B 1 208 ? 1.931   39.515  48.193 1.00 15.10 ?  174  ASN B HD21 1 
ATOM   8236  H HD22 . ASN B 1 208 ? 2.042   38.107  48.666 1.00 15.10 ?  174  ASN B HD22 1 
ATOM   8237  N N    . ILE B 1 209 ? 4.622   34.671  48.551 1.00 12.01 ?  175  ILE B N    1 
ATOM   8238  C CA   . ILE B 1 209 ? 5.025   33.433  49.196 1.00 11.54 ?  175  ILE B CA   1 
ATOM   8239  C C    . ILE B 1 209 ? 5.760   32.530  48.256 1.00 13.37 ?  175  ILE B C    1 
ATOM   8240  O O    . ILE B 1 209 ? 6.675   31.805  48.680 1.00 13.53 ?  175  ILE B O    1 
ATOM   8241  C CB   . ILE B 1 209 ? 3.770   32.809  49.823 1.00 12.88 ?  175  ILE B CB   1 
ATOM   8242  C CG1  . ILE B 1 209 ? 3.251   33.705  50.971 1.00 13.58 ?  175  ILE B CG1  1 
ATOM   8243  C CG2  . ILE B 1 209 ? 4.081   31.405  50.351 1.00 15.01 ?  175  ILE B CG2  1 
ATOM   8244  C CD1  . ILE B 1 209 ? 1.895   33.357  51.467 1.00 19.08 ?  175  ILE B CD1  1 
ATOM   8245  H H    . ILE B 1 209 ? 3.782   34.733  48.373 1.00 14.41 ?  175  ILE B H    1 
ATOM   8246  H HA   . ILE B 1 209 ? 5.665   33.608  49.904 1.00 13.84 ?  175  ILE B HA   1 
ATOM   8247  H HB   . ILE B 1 209 ? 3.085   32.741  49.140 1.00 15.45 ?  175  ILE B HB   1 
ATOM   8248  H HG12 . ILE B 1 209 ? 3.863   33.632  51.720 1.00 16.29 ?  175  ILE B HG12 1 
ATOM   8249  H HG13 . ILE B 1 209 ? 3.220   34.622  50.656 1.00 16.29 ?  175  ILE B HG13 1 
ATOM   8250  H HG21 . ILE B 1 209 ? 3.319   31.082  50.855 1.00 18.01 ?  175  ILE B HG21 1 
ATOM   8251  H HG22 . ILE B 1 209 ? 4.255   30.817  49.599 1.00 18.01 ?  175  ILE B HG22 1 
ATOM   8252  H HG23 . ILE B 1 209 ? 4.862   31.450  50.924 1.00 18.01 ?  175  ILE B HG23 1 
ATOM   8253  H HD11 . ILE B 1 209 ? 1.602   34.040  52.091 1.00 22.89 ?  175  ILE B HD11 1 
ATOM   8254  H HD12 . ILE B 1 209 ? 1.285   33.313  50.715 1.00 22.89 ?  175  ILE B HD12 1 
ATOM   8255  H HD13 . ILE B 1 209 ? 1.933   32.497  51.913 1.00 22.89 ?  175  ILE B HD13 1 
ATOM   8256  N N    . LYS B 1 210 ? 5.490   32.615  46.956 1.00 13.16 ?  176  LYS B N    1 
ATOM   8257  C CA   . LYS B 1 210 ? 6.283   31.880  45.983 1.00 12.63 ?  176  LYS B CA   1 
ATOM   8258  C C    . LYS B 1 210 ? 7.715   32.362  45.965 1.00 13.67 ?  176  LYS B C    1 
ATOM   8259  O O    . LYS B 1 210 ? 8.636   31.571  45.689 1.00 12.99 ?  176  LYS B O    1 
ATOM   8260  C CB   . LYS B 1 210 ? 5.638   32.017  44.614 1.00 11.72 ?  176  LYS B CB   1 
ATOM   8261  C CG   . LYS B 1 210 ? 4.411   31.123  44.444 1.00 12.99 ?  176  LYS B CG   1 
ATOM   8262  C CD   . LYS B 1 210 ? 3.668   31.347  43.137 1.00 12.57 ?  176  LYS B CD   1 
ATOM   8263  C CE   . LYS B 1 210 ? 2.571   30.299  42.875 1.00 12.96 ?  176  LYS B CE   1 
ATOM   8264  N NZ   . LYS B 1 210 ? 1.439   30.419  43.808 1.00 12.77 ?  176  LYS B NZ   1 
ATOM   8265  H H    . LYS B 1 210 ? 4.858   33.088  46.615 1.00 15.80 ?  176  LYS B H    1 
ATOM   8266  H HA   . LYS B 1 210 ? 6.302   30.938  46.214 1.00 15.16 ?  176  LYS B HA   1 
ATOM   8267  H HB2  . LYS B 1 210 ? 5.358   32.937  44.488 1.00 14.07 ?  176  LYS B HB2  1 
ATOM   8268  H HB3  . LYS B 1 210 ? 6.285   31.771  43.935 1.00 14.07 ?  176  LYS B HB3  1 
ATOM   8269  H HG2  . LYS B 1 210 ? 4.694   30.196  44.467 1.00 15.58 ?  176  LYS B HG2  1 
ATOM   8270  H HG3  . LYS B 1 210 ? 3.792   31.300  45.170 1.00 15.58 ?  176  LYS B HG3  1 
ATOM   8271  H HD2  . LYS B 1 210 ? 3.246   32.220  43.161 1.00 15.09 ?  176  LYS B HD2  1 
ATOM   8272  H HD3  . LYS B 1 210 ? 4.301   31.305  42.404 1.00 15.09 ?  176  LYS B HD3  1 
ATOM   8273  H HE2  . LYS B 1 210 ? 2.232   30.415  41.974 1.00 15.55 ?  176  LYS B HE2  1 
ATOM   8274  H HE3  . LYS B 1 210 ? 2.950   29.412  42.975 1.00 15.55 ?  176  LYS B HE3  1 
ATOM   8275  H HZ1  . LYS B 1 210 ? 1.175   31.268  43.859 1.00 15.32 ?  176  LYS B HZ1  1 
ATOM   8276  H HZ2  . LYS B 1 210 ? 0.757   29.921  43.525 1.00 15.32 ?  176  LYS B HZ2  1 
ATOM   8277  H HZ3  . LYS B 1 210 ? 1.681   30.143  44.618 1.00 15.32 ?  176  LYS B HZ3  1 
ATOM   8278  N N    . VAL B 1 211 ? 7.945   33.651  46.211 1.00 12.57 ?  177  VAL B N    1 
ATOM   8279  C CA   . VAL B 1 211 ? 9.330   34.127  46.325 1.00 12.11 ?  177  VAL B CA   1 
ATOM   8280  C C    . VAL B 1 211 ? 9.963   33.647  47.621 1.00 14.70 ?  177  VAL B C    1 
ATOM   8281  O O    . VAL B 1 211 ? 11.160  33.278  47.652 1.00 14.60 ?  177  VAL B O    1 
ATOM   8282  C CB   . VAL B 1 211 ? 9.370   35.664  46.272 1.00 12.78 ?  177  VAL B CB   1 
ATOM   8283  C CG1  . VAL B 1 211 ? 10.765  36.188  46.627 1.00 13.74 ?  177  VAL B CG1  1 
ATOM   8284  C CG2  . VAL B 1 211 ? 8.947   36.173  44.915 1.00 13.87 ?  177  VAL B CG2  1 
ATOM   8285  H H    . VAL B 1 211 ? 7.340   34.253  46.313 1.00 15.08 ?  177  VAL B H    1 
ATOM   8286  H HA   . VAL B 1 211 ? 9.827   33.763  45.576 1.00 14.53 ?  177  VAL B HA   1 
ATOM   8287  H HB   . VAL B 1 211 ? 8.743   36.004  46.929 1.00 15.34 ?  177  VAL B HB   1 
ATOM   8288  H HG11 . VAL B 1 211 ? 10.869  37.081  46.263 1.00 16.48 ?  177  VAL B HG11 1 
ATOM   8289  H HG12 . VAL B 1 211 ? 10.857  36.211  47.593 1.00 16.48 ?  177  VAL B HG12 1 
ATOM   8290  H HG13 . VAL B 1 211 ? 11.431  35.595  46.246 1.00 16.48 ?  177  VAL B HG13 1 
ATOM   8291  H HG21 . VAL B 1 211 ? 9.000   37.141  44.910 1.00 16.64 ?  177  VAL B HG21 1 
ATOM   8292  H HG22 . VAL B 1 211 ? 9.541   35.806  44.241 1.00 16.64 ?  177  VAL B HG22 1 
ATOM   8293  H HG23 . VAL B 1 211 ? 8.036   35.890  44.741 1.00 16.64 ?  177  VAL B HG23 1 
ATOM   8294  N N    . LEU B 1 212 ? 9.226   33.718  48.706 1.00 13.46 ?  178  LEU B N    1 
ATOM   8295  C CA   . LEU B 1 212 ? 9.808   33.605  50.052 1.00 14.85 ?  178  LEU B CA   1 
ATOM   8296  C C    . LEU B 1 212 ? 9.961   32.171  50.550 1.00 16.75 ?  178  LEU B C    1 
ATOM   8297  O O    . LEU B 1 212 ? 10.721  31.944  51.507 1.00 16.64 ?  178  LEU B O    1 
ATOM   8298  C CB   . LEU B 1 212 ? 8.973   34.427  51.038 1.00 13.86 ?  178  LEU B CB   1 
ATOM   8299  C CG   . LEU B 1 212 ? 9.005   35.929  50.725 1.00 14.73 ?  178  LEU B CG   1 
ATOM   8300  C CD1  . LEU B 1 212 ? 7.971   36.636  51.554 1.00 15.90 ?  178  LEU B CD1  1 
ATOM   8301  C CD2  . LEU B 1 212 ? 10.375  36.465  51.022 1.00 14.72 ?  178  LEU B CD2  1 
ATOM   8302  H H    . LEU B 1 212 ? 8.373   33.832  48.705 1.00 16.15 ?  178  LEU B H    1 
ATOM   8303  H HA   . LEU B 1 212 ? 10.704  33.976  50.035 1.00 17.82 ?  178  LEU B HA   1 
ATOM   8304  H HB2  . LEU B 1 212 ? 8.051   34.128  50.996 1.00 16.63 ?  178  LEU B HB2  1 
ATOM   8305  H HB3  . LEU B 1 212 ? 9.324   34.297  51.933 1.00 16.63 ?  178  LEU B HB3  1 
ATOM   8306  H HG   . LEU B 1 212 ? 8.805   36.087  49.789 1.00 17.67 ?  178  LEU B HG   1 
ATOM   8307  H HD11 . LEU B 1 212 ? 8.051   37.592  51.411 1.00 19.08 ?  178  LEU B HD11 1 
ATOM   8308  H HD12 . LEU B 1 212 ? 7.089   36.334  51.284 1.00 19.08 ?  178  LEU B HD12 1 
ATOM   8309  H HD13 . LEU B 1 212 ? 8.120   36.428  52.490 1.00 19.08 ?  178  LEU B HD13 1 
ATOM   8310  H HD21 . LEU B 1 212 ? 10.353  37.433  50.973 1.00 17.66 ?  178  LEU B HD21 1 
ATOM   8311  H HD22 . LEU B 1 212 ? 10.637  36.185  51.913 1.00 17.66 ?  178  LEU B HD22 1 
ATOM   8312  H HD23 . LEU B 1 212 ? 11.000  36.114  50.368 1.00 17.66 ?  178  LEU B HD23 1 
ATOM   8313  N N    . VAL B 1 213 ? 9.268   31.198  49.967 1.00 13.91 ?  179  VAL B N    1 
ATOM   8314  C CA   . VAL B 1 213 ? 9.470   29.788  50.281 1.00 14.69 ?  179  VAL B CA   1 
ATOM   8315  C C    . VAL B 1 213 ? 10.563  29.298  49.333 1.00 15.11 ?  179  VAL B C    1 
ATOM   8316  O O    . VAL B 1 213 ? 10.324  29.230  48.116 1.00 14.30 ?  179  VAL B O    1 
ATOM   8317  C CB   . VAL B 1 213 ? 8.170   29.006  50.071 1.00 14.60 ?  179  VAL B CB   1 
ATOM   8318  C CG1  . VAL B 1 213 ? 8.478   27.523  50.197 1.00 16.59 ?  179  VAL B CG1  1 
ATOM   8319  C CG2  . VAL B 1 213 ? 7.138   29.426  51.065 1.00 16.04 ?  179  VAL B CG2  1 
ATOM   8320  H H    . VAL B 1 213 ? 8.661   31.333  49.374 1.00 16.69 ?  179  VAL B H    1 
ATOM   8321  H HA   . VAL B 1 213 ? 9.762   29.669  51.199 1.00 17.62 ?  179  VAL B HA   1 
ATOM   8322  H HB   . VAL B 1 213 ? 7.806   29.186  49.190 1.00 17.52 ?  179  VAL B HB   1 
ATOM   8323  H HG11 . VAL B 1 213 ? 7.661   27.049  50.417 1.00 19.90 ?  179  VAL B HG11 1 
ATOM   8324  H HG12 . VAL B 1 213 ? 8.830   27.201  49.352 1.00 19.90 ?  179  VAL B HG12 1 
ATOM   8325  H HG13 . VAL B 1 213 ? 9.135   27.396  50.899 1.00 19.90 ?  179  VAL B HG13 1 
ATOM   8326  H HG21 . VAL B 1 213 ? 6.306   28.968  50.868 1.00 19.25 ?  179  VAL B HG21 1 
ATOM   8327  H HG22 . VAL B 1 213 ? 7.443   29.190  51.955 1.00 19.25 ?  179  VAL B HG22 1 
ATOM   8328  H HG23 . VAL B 1 213 ? 7.011   30.385  51.002 1.00 19.25 ?  179  VAL B HG23 1 
ATOM   8329  N N    . PRO B 1 214 ? 11.800  29.049  49.807 1.00 16.85 ?  180  PRO B N    1 
ATOM   8330  C CA   . PRO B 1 214 ? 12.881  28.852  48.831 1.00 16.16 ?  180  PRO B CA   1 
ATOM   8331  C C    . PRO B 1 214 ? 12.652  27.751  47.809 1.00 13.28 ?  180  PRO B C    1 
ATOM   8332  O O    . PRO B 1 214 ? 13.143  27.847  46.686 1.00 15.28 ?  180  PRO B O    1 
ATOM   8333  C CB   . PRO B 1 214 ? 14.129  28.592  49.719 1.00 17.98 ?  180  PRO B CB   1 
ATOM   8334  C CG   . PRO B 1 214 ? 13.809  29.291  50.989 1.00 20.91 ?  180  PRO B CG   1 
ATOM   8335  C CD   . PRO B 1 214 ? 12.315  29.175  51.187 1.00 19.41 ?  180  PRO B CD   1 
ATOM   8336  H HA   . PRO B 1 214 ? 13.000  29.682  48.344 1.00 19.40 ?  180  PRO B HA   1 
ATOM   8337  H HB2  . PRO B 1 214 ? 14.247  27.640  49.861 1.00 21.58 ?  180  PRO B HB2  1 
ATOM   8338  H HB3  . PRO B 1 214 ? 14.921  28.966  49.302 1.00 21.58 ?  180  PRO B HB3  1 
ATOM   8339  H HG2  . PRO B 1 214 ? 14.283  28.865  51.721 1.00 25.09 ?  180  PRO B HG2  1 
ATOM   8340  H HG3  . PRO B 1 214 ? 14.072  30.222  50.921 1.00 25.09 ?  180  PRO B HG3  1 
ATOM   8341  H HD2  . PRO B 1 214 ? 12.096  28.388  51.710 1.00 23.30 ?  180  PRO B HD2  1 
ATOM   8342  H HD3  . PRO B 1 214 ? 11.961  29.969  51.617 1.00 23.30 ?  180  PRO B HD3  1 
ATOM   8343  N N    . SER B 1 215 ? 12.019  26.648  48.228 1.00 16.44 ?  181  SER B N    1 
ATOM   8344  C CA   . SER B 1 215 ? 11.891  25.522  47.307 1.00 15.93 ?  181  SER B CA   1 
ATOM   8345  C C    . SER B 1 215 ? 11.065  25.838  46.060 1.00 16.06 ?  181  SER B C    1 
ATOM   8346  O O    . SER B 1 215 ? 11.274  25.197  45.023 1.00 16.42 ?  181  SER B O    1 
ATOM   8347  C CB   . SER B 1 215 ? 11.275  24.304  48.019 1.00 18.82 ?  181  SER B CB   1 
ATOM   8348  O OG   . SER B 1 215 ? 9.902   24.498  48.270 1.00 16.89 ?  181  SER B OG   1 
ATOM   8349  H H    . SER B 1 215 ? 11.671  26.535  49.006 1.00 19.73 ?  181  SER B H    1 
ATOM   8350  H HA   . SER B 1 215 ? 12.788  25.293  47.018 1.00 19.11 ?  181  SER B HA   1 
ATOM   8351  H HB2  . SER B 1 215 ? 11.383  23.522  47.455 1.00 22.58 ?  181  SER B HB2  1 
ATOM   8352  H HB3  . SER B 1 215 ? 11.733  24.169  48.864 1.00 22.58 ?  181  SER B HB3  1 
ATOM   8353  H HG   . SER B 1 215 ? 9.691   24.143  49.002 1.00 20.27 ?  181  SER B HG   1 
ATOM   8354  N N    . PHE B 1 216 ? 10.172  26.851  46.106 1.00 14.91 ?  182  PHE B N    1 
ATOM   8355  C CA   . PHE B 1 216 ? 9.339   27.118  44.942 1.00 13.86 ?  182  PHE B CA   1 
ATOM   8356  C C    . PHE B 1 216 ? 10.186  27.431  43.725 1.00 13.50 ?  182  PHE B C    1 
ATOM   8357  O O    . PHE B 1 216 ? 10.031  26.821  42.679 1.00 14.99 ?  182  PHE B O    1 
ATOM   8358  C CB   . PHE B 1 216 ? 8.309   28.229  45.205 1.00 14.29 ?  182  PHE B CB   1 
ATOM   8359  C CG   . PHE B 1 216 ? 7.372   28.398  44.028 1.00 14.10 ?  182  PHE B CG   1 
ATOM   8360  C CD1  . PHE B 1 216 ? 6.256   27.567  43.855 1.00 13.75 ?  182  PHE B CD1  1 
ATOM   8361  C CD2  . PHE B 1 216 ? 7.655   29.320  43.020 1.00 13.91 ?  182  PHE B CD2  1 
ATOM   8362  C CE1  . PHE B 1 216 ? 5.431   27.700  42.739 1.00 14.66 ?  182  PHE B CE1  1 
ATOM   8363  C CE2  . PHE B 1 216 ? 6.815   29.456  41.901 1.00 14.61 ?  182  PHE B CE2  1 
ATOM   8364  C CZ   . PHE B 1 216 ? 5.726   28.610  41.749 1.00 14.22 ?  182  PHE B CZ   1 
ATOM   8365  H H    . PHE B 1 216 ? 10.043  27.371  46.779 1.00 17.89 ?  182  PHE B H    1 
ATOM   8366  H HA   . PHE B 1 216 ? 8.825   26.316  44.761 1.00 16.64 ?  182  PHE B HA   1 
ATOM   8367  H HB2  . PHE B 1 216 ? 7.782   28.001  45.987 1.00 17.15 ?  182  PHE B HB2  1 
ATOM   8368  H HB3  . PHE B 1 216 ? 8.772   29.069  45.351 1.00 17.15 ?  182  PHE B HB3  1 
ATOM   8369  H HD1  . PHE B 1 216 ? 6.063   26.919  44.494 1.00 16.50 ?  182  PHE B HD1  1 
ATOM   8370  H HD2  . PHE B 1 216 ? 8.414   29.854  43.089 1.00 16.69 ?  182  PHE B HD2  1 
ATOM   8371  H HE1  . PHE B 1 216 ? 4.672   27.168  42.662 1.00 17.60 ?  182  PHE B HE1  1 
ATOM   8372  H HE2  . PHE B 1 216 ? 6.989   30.112  41.264 1.00 17.53 ?  182  PHE B HE2  1 
ATOM   8373  H HZ   . PHE B 1 216 ? 5.200   28.657  40.984 1.00 17.07 ?  182  PHE B HZ   1 
ATOM   8374  N N    . PHE B 1 217 ? 11.107  28.402  43.836 1.00 13.53 ?  183  PHE B N    1 
ATOM   8375  C CA   . PHE B 1 217 ? 11.976  28.699  42.707 1.00 15.13 ?  183  PHE B CA   1 
ATOM   8376  C C    . PHE B 1 217 ? 13.279  27.877  42.673 1.00 13.01 ?  183  PHE B C    1 
ATOM   8377  O O    . PHE B 1 217 ? 13.798  27.650  41.584 1.00 14.95 ?  183  PHE B O    1 
ATOM   8378  C CB   . PHE B 1 217 ? 12.316  30.210  42.630 1.00 13.48 ?  183  PHE B CB   1 
ATOM   8379  C CG   . PHE B 1 217 ? 11.177  31.023  42.059 1.00 13.02 ?  183  PHE B CG   1 
ATOM   8380  C CD1  . PHE B 1 217 ? 10.730  30.802  40.779 1.00 13.81 ?  183  PHE B CD1  1 
ATOM   8381  C CD2  . PHE B 1 217 ? 10.540  31.980  42.856 1.00 14.34 ?  183  PHE B CD2  1 
ATOM   8382  C CE1  . PHE B 1 217 ? 9.671   31.537  40.248 1.00 13.02 ?  183  PHE B CE1  1 
ATOM   8383  C CE2  . PHE B 1 217 ? 9.481   32.710  42.341 1.00 14.23 ?  183  PHE B CE2  1 
ATOM   8384  C CZ   . PHE B 1 217 ? 9.051   32.486  41.070 1.00 12.75 ?  183  PHE B CZ   1 
ATOM   8385  H H    . PHE B 1 217 ? 11.238  28.882  44.537 1.00 16.23 ?  183  PHE B H    1 
ATOM   8386  H HA   . PHE B 1 217 ? 11.475  28.476  41.906 1.00 18.15 ?  183  PHE B HA   1 
ATOM   8387  H HB2  . PHE B 1 217 ? 12.504  30.539  43.523 1.00 16.17 ?  183  PHE B HB2  1 
ATOM   8388  H HB3  . PHE B 1 217 ? 13.091  30.333  42.061 1.00 16.17 ?  183  PHE B HB3  1 
ATOM   8389  H HD1  . PHE B 1 217 ? 11.142  30.151  40.258 1.00 16.58 ?  183  PHE B HD1  1 
ATOM   8390  H HD2  . PHE B 1 217 ? 10.826  32.125  43.729 1.00 17.21 ?  183  PHE B HD2  1 
ATOM   8391  H HE1  . PHE B 1 217 ? 9.384   31.400  39.373 1.00 15.63 ?  183  PHE B HE1  1 
ATOM   8392  H HE2  . PHE B 1 217 ? 9.064   33.354  42.866 1.00 17.08 ?  183  PHE B HE2  1 
ATOM   8393  H HZ   . PHE B 1 217 ? 8.330   32.973  40.740 1.00 15.30 ?  183  PHE B HZ   1 
ATOM   8394  N N    . SER B 1 218 ? 13.796  27.483  43.830 1.00 16.94 ?  184  SER B N    1 
ATOM   8395  C CA   . SER B 1 218 ? 15.064  26.729  43.780 1.00 17.24 ?  184  SER B CA   1 
ATOM   8396  C C    . SER B 1 218 ? 14.882  25.426  43.003 1.00 19.40 ?  184  SER B C    1 
ATOM   8397  O O    . SER B 1 218 ? 15.779  25.046  42.240 1.00 18.19 ?  184  SER B O    1 
ATOM   8398  C CB   . SER B 1 218 ? 15.646  26.479  45.168 1.00 21.45 ?  184  SER B CB   1 
ATOM   8399  O OG   . SER B 1 218 ? 14.964  25.498  45.882 1.00 21.95 ?  184  SER B OG   1 
ATOM   8400  H H    . SER B 1 218 ? 13.463  27.624  44.610 1.00 20.33 ?  184  SER B H    1 
ATOM   8401  H HA   . SER B 1 218 ? 15.726  27.274  43.325 1.00 20.69 ?  184  SER B HA   1 
ATOM   8402  H HB2  . SER B 1 218 ? 16.569  26.198  45.067 1.00 25.74 ?  184  SER B HB2  1 
ATOM   8403  H HB3  . SER B 1 218 ? 15.605  27.308  45.671 1.00 25.74 ?  184  SER B HB3  1 
ATOM   8404  H HG   . SER B 1 218 ? 15.022  25.650  46.706 1.00 26.34 ?  184  SER B HG   1 
ATOM   8405  N N    . SER B 1 219 ? 13.684  24.821  43.079 1.00 17.04 ?  185  SER B N    1 
ATOM   8406  C CA   . SER B 1 219 ? 13.405  23.577  42.353 1.00 16.88 ?  185  SER B CA   1 
ATOM   8407  C C    . SER B 1 219 ? 13.282  23.793  40.861 1.00 16.16 ?  185  SER B C    1 
ATOM   8408  O O    . SER B 1 219 ? 13.321  22.827  40.082 1.00 20.92 ?  185  SER B O    1 
ATOM   8409  C CB   . SER B 1 219 ? 12.140  22.955  42.901 1.00 20.48 ?  185  SER B CB   1 
ATOM   8410  O OG   . SER B 1 219 ? 10.988  23.751  42.603 1.00 19.10 ?  185  SER B OG   1 
ATOM   8411  H H    . SER B 1 219 ? 13.020  25.112  43.543 1.00 20.45 ?  185  SER B H    1 
ATOM   8412  H HA   . SER B 1 219 ? 14.135  22.954  42.492 1.00 20.26 ?  185  SER B HA   1 
ATOM   8413  H HB2  . SER B 1 219 ? 12.026  22.078  42.502 1.00 24.58 ?  185  SER B HB2  1 
ATOM   8414  H HB3  . SER B 1 219 ? 12.224  22.873  43.863 1.00 24.58 ?  185  SER B HB3  1 
ATOM   8415  H HG   . SER B 1 219 ? 11.072  24.515  42.941 1.00 22.92 ?  185  SER B HG   1 
ATOM   8416  N N    . LYS B 1 220 ? 13.126  25.043  40.411 1.00 15.41 ?  186  LYS B N    1 
ATOM   8417  C CA   . LYS B 1 220 ? 12.996  25.396  39.015 1.00 15.63 ?  186  LYS B CA   1 
ATOM   8418  C C    . LYS B 1 220 ? 14.276  25.963  38.402 1.00 16.14 ?  186  LYS B C    1 
ATOM   8419  O O    . LYS B 1 220 ? 14.577  25.707  37.246 1.00 18.65 ?  186  LYS B O    1 
ATOM   8420  C CB   . LYS B 1 220 ? 11.856  26.444  38.837 1.00 16.24 ?  186  LYS B CB   1 
ATOM   8421  C CG   . LYS B 1 220 ? 10.466  25.935  39.261 1.00 15.80 ?  186  LYS B CG   1 
ATOM   8422  C CD   . LYS B 1 220 ? 9.463   27.083  39.207 1.00 18.33 ?  186  LYS B CD   1 
ATOM   8423  C CE   . LYS B 1 220 ? 8.050   26.601  39.518 1.00 17.54 ?  186  LYS B CE   1 
ATOM   8424  N NZ   . LYS B 1 220 ? 7.891   26.073  40.865 1.00 20.33 ?  186  LYS B NZ   1 
ATOM   8425  H H    . LYS B 1 220 ? 13.091  25.729  40.929 1.00 18.49 ?  186  LYS B H    1 
ATOM   8426  H HA   . LYS B 1 220 ? 12.765  24.592  38.524 1.00 18.76 ?  186  LYS B HA   1 
ATOM   8427  H HB2  . LYS B 1 220 ? 12.063  27.223  39.376 1.00 19.48 ?  186  LYS B HB2  1 
ATOM   8428  H HB3  . LYS B 1 220 ? 11.806  26.693  37.900 1.00 19.48 ?  186  LYS B HB3  1 
ATOM   8429  H HG2  . LYS B 1 220 ? 10.173  25.235  38.656 1.00 18.96 ?  186  LYS B HG2  1 
ATOM   8430  H HG3  . LYS B 1 220 ? 10.503  25.595  40.169 1.00 18.96 ?  186  LYS B HG3  1 
ATOM   8431  H HD2  . LYS B 1 220 ? 9.707   27.756  39.862 1.00 22.00 ?  186  LYS B HD2  1 
ATOM   8432  H HD3  . LYS B 1 220 ? 9.465   27.471  38.317 1.00 22.00 ?  186  LYS B HD3  1 
ATOM   8433  H HE2  . LYS B 1 220 ? 7.437   27.346  39.418 1.00 21.05 ?  186  LYS B HE2  1 
ATOM   8434  H HE3  . LYS B 1 220 ? 7.817   25.894  38.895 1.00 21.05 ?  186  LYS B HE3  1 
ATOM   8435  H HZ1  . LYS B 1 220 ? 8.344   25.312  40.949 1.00 24.40 ?  186  LYS B HZ1  1 
ATOM   8436  H HZ2  . LYS B 1 220 ? 8.199   26.659  41.460 1.00 24.40 ?  186  LYS B HZ2  1 
ATOM   8437  H HZ3  . LYS B 1 220 ? 7.031   25.918  41.032 1.00 24.40 ?  186  LYS B HZ3  1 
ATOM   8438  N N    . VAL B 1 221 ? 14.982  26.842  39.119 1.00 16.43 ?  187  VAL B N    1 
ATOM   8439  C CA   . VAL B 1 221 ? 16.050  27.634  38.524 1.00 17.70 ?  187  VAL B CA   1 
ATOM   8440  C C    . VAL B 1 221 ? 17.348  27.556  39.303 1.00 21.49 ?  187  VAL B C    1 
ATOM   8441  O O    . VAL B 1 221 ? 18.314  28.247  38.937 1.00 21.12 ?  187  VAL B O    1 
ATOM   8442  C CB   . VAL B 1 221 ? 15.631  29.107  38.300 1.00 16.66 ?  187  VAL B CB   1 
ATOM   8443  C CG1  . VAL B 1 221 ? 14.581  29.182  37.229 1.00 18.38 ?  187  VAL B CG1  1 
ATOM   8444  C CG2  . VAL B 1 221 ? 15.126  29.757  39.614 1.00 16.70 ?  187  VAL B CG2  1 
ATOM   8445  H H    . VAL B 1 221 ? 14.856  26.995  39.956 1.00 19.71 ?  187  VAL B H    1 
ATOM   8446  H HA   . VAL B 1 221 ? 16.238  27.264  37.648 1.00 21.24 ?  187  VAL B HA   1 
ATOM   8447  H HB   . VAL B 1 221 ? 16.408  29.611  38.010 1.00 19.99 ?  187  VAL B HB   1 
ATOM   8448  H HG11 . VAL B 1 221 ? 14.310  30.107  37.117 1.00 22.05 ?  187  VAL B HG11 1 
ATOM   8449  H HG12 . VAL B 1 221 ? 14.952  28.843  36.399 1.00 22.05 ?  187  VAL B HG12 1 
ATOM   8450  H HG13 . VAL B 1 221 ? 13.820  28.644  37.496 1.00 22.05 ?  187  VAL B HG13 1 
ATOM   8451  H HG21 . VAL B 1 221 ? 15.159  30.722  39.522 1.00 20.04 ?  187  VAL B HG21 1 
ATOM   8452  H HG22 . VAL B 1 221 ? 14.214  29.471  39.777 1.00 20.04 ?  187  VAL B HG22 1 
ATOM   8453  H HG23 . VAL B 1 221 ? 15.697  29.474  40.346 1.00 20.04 ?  187  VAL B HG23 1 
ATOM   8454  N N    . GLY B 1 222 ? 17.384  26.810  40.383 1.00 19.11 ?  188  GLY B N    1 
ATOM   8455  C CA   . GLY B 1 222 ? 18.614  26.623  41.122 1.00 18.17 ?  188  GLY B CA   1 
ATOM   8456  C C    . GLY B 1 222 ? 18.641  27.511  42.350 1.00 20.83 ?  188  GLY B C    1 
ATOM   8457  O O    . GLY B 1 222 ? 17.929  28.531  42.452 1.00 19.94 ?  188  GLY B O    1 
ATOM   8458  H H    . GLY B 1 222 ? 16.705  26.398  40.713 1.00 22.93 ?  188  GLY B H    1 
ATOM   8459  H HA2  . GLY B 1 222 ? 18.690  25.698  41.403 1.00 21.80 ?  188  GLY B HA2  1 
ATOM   8460  H HA3  . GLY B 1 222 ? 19.372  26.845  40.558 1.00 21.80 ?  188  GLY B HA3  1 
ATOM   8461  N N    . VAL B 1 223 ? 19.497  27.131  43.294 1.00 20.84 ?  189  VAL B N    1 
ATOM   8462  C CA   . VAL B 1 223 ? 19.508  27.772  44.604 1.00 21.49 ?  189  VAL B CA   1 
ATOM   8463  C C    . VAL B 1 223 ? 20.070  29.184  44.512 1.00 19.43 ?  189  VAL B C    1 
ATOM   8464  O O    . VAL B 1 223 ? 19.533  30.103  45.154 1.00 21.95 ?  189  VAL B O    1 
ATOM   8465  C CB   . VAL B 1 223 ? 20.287  26.934  45.644 1.00 21.99 ?  189  VAL B CB   1 
ATOM   8466  C CG1  . VAL B 1 223 ? 19.517  25.663  45.958 1.00 20.87 ?  189  VAL B CG1  1 
ATOM   8467  C CG2  . VAL B 1 223 ? 21.715  26.633  45.155 1.00 24.07 ?  189  VAL B CG2  1 
ATOM   8468  H H    . VAL B 1 223 ? 20.080  26.505  43.202 1.00 25.01 ?  189  VAL B H    1 
ATOM   8469  H HA   . VAL B 1 223 ? 18.586  27.824  44.901 1.00 25.78 ?  189  VAL B HA   1 
ATOM   8470  H HB   . VAL B 1 223 ? 20.378  27.443  46.465 1.00 26.38 ?  189  VAL B HB   1 
ATOM   8471  H HG11 . VAL B 1 223 ? 20.063  25.094  46.524 1.00 25.04 ?  189  VAL B HG11 1 
ATOM   8472  H HG12 . VAL B 1 223 ? 18.695  25.896  46.418 1.00 25.04 ?  189  VAL B HG12 1 
ATOM   8473  H HG13 . VAL B 1 223 ? 19.312  25.204  45.128 1.00 25.04 ?  189  VAL B HG13 1 
ATOM   8474  H HG21 . VAL B 1 223 ? 22.176  26.110  45.830 1.00 28.88 ?  189  VAL B HG21 1 
ATOM   8475  H HG22 . VAL B 1 223 ? 21.665  26.132  44.326 1.00 28.88 ?  189  VAL B HG22 1 
ATOM   8476  H HG23 . VAL B 1 223 ? 22.182  27.470  45.009 1.00 28.88 ?  189  VAL B HG23 1 
ATOM   8477  N N    . ASN B 1 224 ? 21.071  29.410  43.632 1.00 19.75 ?  190  ASN B N    1 
ATOM   8478  C CA   . ASN B 1 224 ? 21.622  30.762  43.543 1.00 20.99 ?  190  ASN B CA   1 
ATOM   8479  C C    . ASN B 1 224 ? 20.583  31.724  43.003 1.00 25.42 ?  190  ASN B C    1 
ATOM   8480  O O    . ASN B 1 224 ? 20.432  32.852  43.496 1.00 21.93 ?  190  ASN B O    1 
ATOM   8481  C CB   . ASN B 1 224 ? 22.894  30.857  42.672 1.00 24.53 ?  190  ASN B CB   1 
ATOM   8482  C CG   . ASN B 1 224 ? 24.015  29.907  43.085 1.00 21.10 ?  190  ASN B CG   1 
ATOM   8483  O OD1  . ASN B 1 224 ? 24.206  29.518  44.283 1.00 22.08 ?  190  ASN B OD1  1 
ATOM   8484  N ND2  . ASN B 1 224 ? 24.816  29.553  42.076 1.00 23.29 ?  190  ASN B ND2  1 
ATOM   8485  H H    . ASN B 1 224 ? 21.423  28.826  43.109 1.00 23.70 ?  190  ASN B H    1 
ATOM   8486  H HA   . ASN B 1 224 ? 21.888  31.006  44.443 1.00 25.19 ?  190  ASN B HA   1 
ATOM   8487  H HB2  . ASN B 1 224 ? 22.657  30.650  41.755 1.00 29.44 ?  190  ASN B HB2  1 
ATOM   8488  H HB3  . ASN B 1 224 ? 23.241  31.761  42.729 1.00 29.44 ?  190  ASN B HB3  1 
ATOM   8489  H HD21 . ASN B 1 224 ? 24.673  29.859  41.285 1.00 27.94 ?  190  ASN B HD21 1 
ATOM   8490  H HD22 . ASN B 1 224 ? 25.476  29.019  42.218 1.00 27.94 ?  190  ASN B HD22 1 
ATOM   8491  N N    . LYS B 1 225 ? 19.875  31.306  41.970 1.00 21.11 ?  191  LYS B N    1 
ATOM   8492  C CA   . LYS B 1 225 ? 18.886  32.192  41.378 1.00 17.26 ?  191  LYS B CA   1 
ATOM   8493  C C    . LYS B 1 225 ? 17.740  32.483  42.354 1.00 20.44 ?  191  LYS B C    1 
ATOM   8494  O O    . LYS B 1 225 ? 17.278  33.627  42.421 1.00 17.58 ?  191  LYS B O    1 
ATOM   8495  C CB   . LYS B 1 225 ? 18.391  31.577  40.070 1.00 20.27 ?  191  LYS B CB   1 
ATOM   8496  C CG   . LYS B 1 225 ? 17.550  32.467  39.225 1.00 19.72 ?  191  LYS B CG   1 
ATOM   8497  C CD   . LYS B 1 225 ? 18.360  33.632  38.683 1.00 25.22 ?  191  LYS B CD   1 
ATOM   8498  C CE   . LYS B 1 225 ? 17.586  34.463  37.700 1.00 24.61 ?  191  LYS B CE   1 
ATOM   8499  N NZ   . LYS B 1 225 ? 18.449  35.317  36.840 1.00 21.20 ?  191  LYS B NZ   1 
ATOM   8500  H H    . LYS B 1 225 ? 19.945  30.533  41.599 1.00 25.33 ?  191  LYS B H    1 
ATOM   8501  H HA   . LYS B 1 225 ? 19.290  33.048  41.167 1.00 20.71 ?  191  LYS B HA   1 
ATOM   8502  H HB2  . LYS B 1 225 ? 19.162  31.320  39.541 1.00 24.32 ?  191  LYS B HB2  1 
ATOM   8503  H HB3  . LYS B 1 225 ? 17.859  30.794  40.283 1.00 24.32 ?  191  LYS B HB3  1 
ATOM   8504  H HG2  . LYS B 1 225 ? 17.199  31.963  38.474 1.00 23.66 ?  191  LYS B HG2  1 
ATOM   8505  H HG3  . LYS B 1 225 ? 16.820  32.822  39.757 1.00 23.66 ?  191  LYS B HG3  1 
ATOM   8506  H HD2  . LYS B 1 225 ? 18.623  34.205  39.420 1.00 30.26 ?  191  LYS B HD2  1 
ATOM   8507  H HD3  . LYS B 1 225 ? 19.147  33.289  38.232 1.00 30.26 ?  191  LYS B HD3  1 
ATOM   8508  H HE2  . LYS B 1 225 ? 17.080  33.873  37.120 1.00 29.53 ?  191  LYS B HE2  1 
ATOM   8509  H HE3  . LYS B 1 225 ? 16.984  35.046  38.188 1.00 29.53 ?  191  LYS B HE3  1 
ATOM   8510  H HZ1  . LYS B 1 225 ? 18.878  35.916  37.338 1.00 25.44 ?  191  LYS B HZ1  1 
ATOM   8511  H HZ2  . LYS B 1 225 ? 19.046  34.814  36.413 1.00 25.44 ?  191  LYS B HZ2  1 
ATOM   8512  H HZ3  . LYS B 1 225 ? 17.951  35.745  36.239 1.00 25.44 ?  191  LYS B HZ3  1 
ATOM   8513  N N    . GLN B 1 226 ? 17.298  31.517  43.152 1.00 18.19 ?  192  GLN B N    1 
ATOM   8514  C CA   . GLN B 1 226 ? 16.247  31.796  44.126 1.00 16.27 ?  192  GLN B CA   1 
ATOM   8515  C C    . GLN B 1 226 ? 16.672  32.861  45.114 1.00 18.27 ?  192  GLN B C    1 
ATOM   8516  O O    . GLN B 1 226 ? 15.890  33.760  45.461 1.00 16.17 ?  192  GLN B O    1 
ATOM   8517  C CB   . GLN B 1 226 ? 15.754  30.546  44.871 1.00 16.33 ?  192  GLN B CB   1 
ATOM   8518  C CG   . GLN B 1 226 ? 14.537  30.791  45.791 1.00 16.38 ?  192  GLN B CG   1 
ATOM   8519  C CD   . GLN B 1 226 ? 14.863  31.466  47.089 1.00 19.15 ?  192  GLN B CD   1 
ATOM   8520  O OE1  . GLN B 1 226 ? 16.012  31.356  47.562 1.00 18.30 ?  192  GLN B OE1  1 
ATOM   8521  N NE2  . GLN B 1 226 ? 13.895  32.152  47.705 1.00 18.27 ?  192  GLN B NE2  1 
ATOM   8522  H H    . GLN B 1 226 ? 17.583  30.705  43.151 1.00 21.82 ?  192  GLN B H    1 
ATOM   8523  H HA   . GLN B 1 226 ? 15.488  32.117  43.615 1.00 19.53 ?  192  GLN B HA   1 
ATOM   8524  H HB2  . GLN B 1 226 ? 15.498  29.877  44.217 1.00 19.60 ?  192  GLN B HB2  1 
ATOM   8525  H HB3  . GLN B 1 226 ? 16.477  30.211  45.424 1.00 19.60 ?  192  GLN B HB3  1 
ATOM   8526  H HG2  . GLN B 1 226 ? 13.901  31.353  45.321 1.00 19.66 ?  192  GLN B HG2  1 
ATOM   8527  H HG3  . GLN B 1 226 ? 14.131  29.935  46.001 1.00 19.66 ?  192  GLN B HG3  1 
ATOM   8528  H HE21 . GLN B 1 226 ? 13.111  32.196  47.356 1.00 21.92 ?  192  GLN B HE21 1 
ATOM   8529  H HE22 . GLN B 1 226 ? 14.057  32.548  48.451 1.00 21.92 ?  192  GLN B HE22 1 
ATOM   8530  N N    . ALA B 1 227 ? 17.917  32.784  45.610 1.00 20.09 ?  193  ALA B N    1 
ATOM   8531  C CA   . ALA B 1 227 ? 18.371  33.764  46.590 1.00 18.24 ?  193  ALA B CA   1 
ATOM   8532  C C    . ALA B 1 227 ? 18.381  35.150  45.969 1.00 15.70 ?  193  ALA B C    1 
ATOM   8533  O O    . ALA B 1 227 ? 18.020  36.139  46.636 1.00 18.52 ?  193  ALA B O    1 
ATOM   8534  C CB   . ALA B 1 227 ? 19.784  33.386  47.059 1.00 20.55 ?  193  ALA B CB   1 
ATOM   8535  H H    . ALA B 1 227 ? 18.499  32.188  45.397 1.00 24.11 ?  193  ALA B H    1 
ATOM   8536  H HA   . ALA B 1 227 ? 17.780  33.767  47.359 1.00 21.88 ?  193  ALA B HA   1 
ATOM   8537  H HB1  . ALA B 1 227 ? 20.070  34.016  47.739 1.00 24.65 ?  193  ALA B HB1  1 
ATOM   8538  H HB2  . ALA B 1 227 ? 19.765  32.489  47.428 1.00 24.65 ?  193  ALA B HB2  1 
ATOM   8539  H HB3  . ALA B 1 227 ? 20.388  33.420  46.301 1.00 24.65 ?  193  ALA B HB3  1 
ATOM   8540  N N    . GLU B 1 228 ? 18.748  35.237  44.712 1.00 15.02 ?  194  GLU B N    1 
ATOM   8541  C CA   . GLU B 1 228 ? 18.770  36.505  43.999 1.00 16.40 ?  194  GLU B CA   1 
ATOM   8542  C C    . GLU B 1 228 ? 17.349  37.031  43.755 1.00 18.38 ?  194  GLU B C    1 
ATOM   8543  O O    . GLU B 1 228 ? 17.114  38.251  43.853 1.00 17.34 ?  194  GLU B O    1 
ATOM   8544  C CB   . GLU B 1 228 ? 19.473  36.304  42.676 1.00 20.02 ?  194  GLU B CB   1 
ATOM   8545  C CG   . GLU B 1 228 ? 21.010  36.208  42.782 1.00 20.14 ?  194  GLU B CG   1 
ATOM   8546  C CD   . GLU B 1 228 ? 21.661  37.200  43.771 1.00 42.67 ?  194  GLU B CD   1 
ATOM   8547  O OE1  . GLU B 1 228 ? 22.601  36.779  44.480 1.00 38.84 ?  194  GLU B OE1  1 
ATOM   8548  O OE2  . GLU B 1 228 ? 21.264  38.399  43.824 1.00 36.93 ?  194  GLU B OE2  1 
ATOM   8549  H H    . GLU B 1 228 ? 18.995  34.568  44.232 1.00 18.03 ?  194  GLU B H    1 
ATOM   8550  H HA   . GLU B 1 228 ? 19.250  37.164  44.525 1.00 19.68 ?  194  GLU B HA   1 
ATOM   8551  H HB2  . GLU B 1 228 ? 19.155  35.478  42.279 1.00 24.03 ?  194  GLU B HB2  1 
ATOM   8552  H HB3  . GLU B 1 228 ? 19.265  37.053  42.097 1.00 24.03 ?  194  GLU B HB3  1 
ATOM   8553  H HG2  . GLU B 1 228 ? 21.243  35.313  43.073 1.00 24.17 ?  194  GLU B HG2  1 
ATOM   8554  H HG3  . GLU B 1 228 ? 21.390  36.382  41.906 1.00 24.17 ?  194  GLU B HG3  1 
ATOM   8555  N N    . ILE B 1 229 ? 16.400  36.148  43.415 1.00 15.87 ?  195  ILE B N    1 
ATOM   8556  C CA   . ILE B 1 229 ? 14.994  36.554  43.278 1.00 13.96 ?  195  ILE B CA   1 
ATOM   8557  C C    . ILE B 1 229 ? 14.497  37.147  44.585 1.00 14.53 ?  195  ILE B C    1 
ATOM   8558  O O    . ILE B 1 229 ? 13.838  38.196  44.590 1.00 14.13 ?  195  ILE B O    1 
ATOM   8559  C CB   . ILE B 1 229 ? 14.156  35.325  42.855 1.00 14.24 ?  195  ILE B CB   1 
ATOM   8560  C CG1  . ILE B 1 229 ? 14.469  34.960  41.428 1.00 15.63 ?  195  ILE B CG1  1 
ATOM   8561  C CG2  . ILE B 1 229 ? 12.636  35.625  42.978 1.00 14.52 ?  195  ILE B CG2  1 
ATOM   8562  C CD1  . ILE B 1 229 ? 13.885  33.617  40.971 1.00 16.50 ?  195  ILE B CD1  1 
ATOM   8563  H H    . ILE B 1 229 ? 16.541  35.314  43.260 1.00 19.04 ?  195  ILE B H    1 
ATOM   8564  H HA   . ILE B 1 229 ? 14.914  37.236  42.593 1.00 16.75 ?  195  ILE B HA   1 
ATOM   8565  H HB   . ILE B 1 229 ? 14.385  34.589  43.444 1.00 17.09 ?  195  ILE B HB   1 
ATOM   8566  H HG12 . ILE B 1 229 ? 14.109  35.648  40.847 1.00 18.75 ?  195  ILE B HG12 1 
ATOM   8567  H HG13 . ILE B 1 229 ? 15.432  34.910  41.326 1.00 18.75 ?  195  ILE B HG13 1 
ATOM   8568  H HG21 . ILE B 1 229 ? 12.136  34.847  42.684 1.00 17.42 ?  195  ILE B HG21 1 
ATOM   8569  H HG22 . ILE B 1 229 ? 12.427  35.821  43.905 1.00 17.42 ?  195  ILE B HG22 1 
ATOM   8570  H HG23 . ILE B 1 229 ? 12.418  36.388  42.421 1.00 17.42 ?  195  ILE B HG23 1 
ATOM   8571  H HD11 . ILE B 1 229 ? 14.171  33.441  40.061 1.00 19.79 ?  195  ILE B HD11 1 
ATOM   8572  H HD12 . ILE B 1 229 ? 14.206  32.916  41.560 1.00 19.79 ?  195  ILE B HD12 1 
ATOM   8573  H HD13 . ILE B 1 229 ? 12.917  33.664  41.011 1.00 19.79 ?  195  ILE B HD13 1 
ATOM   8574  N N    . GLU B 1 230 ? 14.826  36.514  45.712 1.00 14.53 ?  196  GLU B N    1 
ATOM   8575  C CA   . GLU B 1 230 ? 14.398  36.988  47.007 1.00 15.05 ?  196  GLU B CA   1 
ATOM   8576  C C    . GLU B 1 230 ? 14.985  38.360  47.320 1.00 17.32 ?  196  GLU B C    1 
ATOM   8577  O O    . GLU B 1 230 ? 14.271  39.269  47.783 1.00 15.52 ?  196  GLU B O    1 
ATOM   8578  C CB   . GLU B 1 230 ? 14.787  35.964  48.079 1.00 17.68 ?  196  GLU B CB   1 
ATOM   8579  C CG   . GLU B 1 230 ? 14.342  36.328  49.478 1.00 16.95 ?  196  GLU B CG   1 
ATOM   8580  C CD   . GLU B 1 230 ? 14.622  35.241  50.488 1.00 24.53 ?  196  GLU B CD   1 
ATOM   8581  O OE1  . GLU B 1 230 ? 14.327  34.048  50.206 1.00 21.92 ?  196  GLU B OE1  1 
ATOM   8582  O OE2  . GLU B 1 230 ? 15.150  35.566  51.571 1.00 27.30 ?  196  GLU B OE2  1 
ATOM   8583  H H    . GLU B 1 230 ? 15.303  35.799  45.746 1.00 17.44 ?  196  GLU B H    1 
ATOM   8584  H HA   . GLU B 1 230 ? 13.432  37.079  47.009 1.00 18.06 ?  196  GLU B HA   1 
ATOM   8585  H HB2  . GLU B 1 230 ? 14.383  35.112  47.854 1.00 21.22 ?  196  GLU B HB2  1 
ATOM   8586  H HB3  . GLU B 1 230 ? 15.753  35.880  48.090 1.00 21.22 ?  196  GLU B HB3  1 
ATOM   8587  H HG2  . GLU B 1 230 ? 14.813  37.127  49.761 1.00 20.34 ?  196  GLU B HG2  1 
ATOM   8588  H HG3  . GLU B 1 230 ? 13.386  36.491  49.473 1.00 20.34 ?  196  GLU B HG3  1 
ATOM   8589  N N    . ASN B 1 231 ? 16.285  38.535  47.067 1.00 16.37 ?  197  ASN B N    1 
ATOM   8590  C CA   . ASN B 1 231 ? 16.912  39.827  47.326 1.00 16.88 ?  197  ASN B CA   1 
ATOM   8591  C C    . ASN B 1 231 ? 16.245  40.929  46.510 1.00 17.17 ?  197  ASN B C    1 
ATOM   8592  O O    . ASN B 1 231 ? 15.949  42.029  47.026 1.00 16.83 ?  197  ASN B O    1 
ATOM   8593  C CB   . ASN B 1 231 ? 18.405  39.733  46.985 1.00 20.75 ?  197  ASN B CB   1 
ATOM   8594  C CG   . ASN B 1 231 ? 19.115  41.051  47.138 1.00 26.41 ?  197  ASN B CG   1 
ATOM   8595  O OD1  . ASN B 1 231 ? 19.333  41.494  48.253 1.00 30.79 ?  197  ASN B OD1  1 
ATOM   8596  N ND2  . ASN B 1 231 ? 19.465  41.682  46.022 1.00 25.40 ?  197  ASN B ND2  1 
ATOM   8597  H H    . ASN B 1 231 ? 16.812  37.933  46.753 1.00 19.64 ?  197  ASN B H    1 
ATOM   8598  H HA   . ASN B 1 231 ? 16.818  40.052  48.265 1.00 20.25 ?  197  ASN B HA   1 
ATOM   8599  H HB2  . ASN B 1 231 ? 18.826  39.093  47.581 1.00 24.90 ?  197  ASN B HB2  1 
ATOM   8600  H HB3  . ASN B 1 231 ? 18.502  39.443  46.065 1.00 24.90 ?  197  ASN B HB3  1 
ATOM   8601  H HD21 . ASN B 1 231 ? 19.873  42.438  46.065 1.00 30.49 ?  197  ASN B HD21 1 
ATOM   8602  H HD22 . ASN B 1 231 ? 19.283  41.335  45.256 1.00 30.49 ?  197  ASN B HD22 1 
ATOM   8603  N N    . SER B 1 232 ? 16.008  40.662  45.222 1.00 15.14 ?  198  SER B N    1 
ATOM   8604  C CA   . SER B 1 232 ? 15.374  41.637  44.356 1.00 13.65 ?  198  SER B CA   1 
ATOM   8605  C C    . SER B 1 232 ? 13.943  41.934  44.807 1.00 16.10 ?  198  SER B C    1 
ATOM   8606  O O    . SER B 1 232 ? 13.496  43.087  44.769 1.00 16.35 ?  198  SER B O    1 
ATOM   8607  C CB   . SER B 1 232 ? 15.403  41.182  42.906 1.00 15.94 ?  198  SER B CB   1 
ATOM   8608  O OG   . SER B 1 232 ? 16.749  40.991  42.453 1.00 18.48 ?  198  SER B OG   1 
ATOM   8609  H H    . SER B 1 232 ? 16.207  39.922  44.831 1.00 18.16 ?  198  SER B H    1 
ATOM   8610  H HA   . SER B 1 232 ? 15.882  42.462  44.405 1.00 16.38 ?  198  SER B HA   1 
ATOM   8611  H HB2  . SER B 1 232 ? 14.923  40.343  42.830 1.00 19.13 ?  198  SER B HB2  1 
ATOM   8612  H HB3  . SER B 1 232 ? 14.978  41.858  42.355 1.00 19.13 ?  198  SER B HB3  1 
ATOM   8613  H HG   . SER B 1 232 ? 17.106  41.734  42.292 1.00 22.18 ?  198  SER B HG   1 
ATOM   8614  N N    . TYR B 1 233 ? 13.214  40.905  45.244 1.00 14.48 ?  199  TYR B N    1 
ATOM   8615  C CA   . TYR B 1 233 ? 11.849  41.085  45.754 1.00 14.64 ?  199  TYR B CA   1 
ATOM   8616  C C    . TYR B 1 233 ? 11.819  42.055  46.925 1.00 14.45 ?  199  TYR B C    1 
ATOM   8617  O O    . TYR B 1 233 ? 10.993  42.975  46.957 1.00 14.52 ?  199  TYR B O    1 
ATOM   8618  C CB   . TYR B 1 233 ? 11.270  39.704  46.153 1.00 13.68 ?  199  TYR B CB   1 
ATOM   8619  C CG   . TYR B 1 233 ? 10.046  39.806  47.038 1.00 13.30 ?  199  TYR B CG   1 
ATOM   8620  C CD1  . TYR B 1 233 ? 8.769   39.993  46.474 1.00 12.91 ?  199  TYR B CD1  1 
ATOM   8621  C CD2  . TYR B 1 233 ? 10.143  39.765  48.423 1.00 14.48 ?  199  TYR B CD2  1 
ATOM   8622  C CE1  . TYR B 1 233 ? 7.657   40.120  47.269 1.00 12.98 ?  199  TYR B CE1  1 
ATOM   8623  C CE2  . TYR B 1 233 ? 9.034   39.903  49.236 1.00 12.75 ?  199  TYR B CE2  1 
ATOM   8624  C CZ   . TYR B 1 233 ? 7.774   40.060  48.637 1.00 12.27 ?  199  TYR B CZ   1 
ATOM   8625  O OH   . TYR B 1 233 ? 6.698   40.221  49.461 1.00 13.09 ?  199  TYR B OH   1 
ATOM   8626  H H    . TYR B 1 233 ? 13.484  40.089  45.257 1.00 17.37 ?  199  TYR B H    1 
ATOM   8627  H HA   . TYR B 1 233 ? 11.291  41.461  45.056 1.00 17.57 ?  199  TYR B HA   1 
ATOM   8628  H HB2  . TYR B 1 233 ? 11.019  39.224  45.349 1.00 16.42 ?  199  TYR B HB2  1 
ATOM   8629  H HB3  . TYR B 1 233 ? 11.948  39.207  46.638 1.00 16.42 ?  199  TYR B HB3  1 
ATOM   8630  H HD1  . TYR B 1 233 ? 8.678   40.030  45.549 1.00 15.49 ?  199  TYR B HD1  1 
ATOM   8631  H HD2  . TYR B 1 233 ? 10.977  39.641  48.814 1.00 17.38 ?  199  TYR B HD2  1 
ATOM   8632  H HE1  . TYR B 1 233 ? 6.822   40.248  46.881 1.00 15.58 ?  199  TYR B HE1  1 
ATOM   8633  H HE2  . TYR B 1 233 ? 9.121   39.893  50.162 1.00 15.30 ?  199  TYR B HE2  1 
ATOM   8634  H HH   . TYR B 1 233 ? 6.024   40.445  49.013 1.00 15.70 ?  199  TYR B HH   1 
ATOM   8635  N N    . PHE B 1 234 ? 12.730  41.901  47.895 1.00 13.91 ?  200  PHE B N    1 
ATOM   8636  C CA   . PHE B 1 234 ? 12.743  42.832  49.025 1.00 14.35 ?  200  PHE B CA   1 
ATOM   8637  C C    . PHE B 1 234 ? 13.028  44.268  48.575 1.00 14.88 ?  200  PHE B C    1 
ATOM   8638  O O    . PHE B 1 234 ? 12.412  45.205  49.083 1.00 15.69 ?  200  PHE B O    1 
ATOM   8639  C CB   . PHE B 1 234 ? 13.753  42.378  50.074 1.00 15.91 ?  200  PHE B CB   1 
ATOM   8640  C CG   . PHE B 1 234 ? 13.320  41.175  50.857 1.00 17.98 ?  200  PHE B CG   1 
ATOM   8641  C CD1  . PHE B 1 234 ? 12.060  41.100  51.419 1.00 21.43 ?  200  PHE B CD1  1 
ATOM   8642  C CD2  . PHE B 1 234 ? 14.189  40.106  51.042 1.00 23.46 ?  200  PHE B CD2  1 
ATOM   8643  C CE1  . PHE B 1 234 ? 11.685  39.966  52.142 1.00 26.56 ?  200  PHE B CE1  1 
ATOM   8644  C CE2  . PHE B 1 234 ? 13.802  38.998  51.772 1.00 26.67 ?  200  PHE B CE2  1 
ATOM   8645  C CZ   . PHE B 1 234 ? 12.568  38.945  52.317 1.00 22.15 ?  200  PHE B CZ   1 
ATOM   8646  H H    . PHE B 1 234 ? 13.331  41.287  47.919 1.00 16.69 ?  200  PHE B H    1 
ATOM   8647  H HA   . PHE B 1 234 ? 11.865  42.826  49.437 1.00 17.22 ?  200  PHE B HA   1 
ATOM   8648  H HB2  . PHE B 1 234 ? 14.585  42.156  49.629 1.00 19.10 ?  200  PHE B HB2  1 
ATOM   8649  H HB3  . PHE B 1 234 ? 13.896  43.103  50.702 1.00 19.10 ?  200  PHE B HB3  1 
ATOM   8650  H HD1  . PHE B 1 234 ? 11.462  41.805  51.316 1.00 25.71 ?  200  PHE B HD1  1 
ATOM   8651  H HD2  . PHE B 1 234 ? 15.041  40.136  50.670 1.00 28.15 ?  200  PHE B HD2  1 
ATOM   8652  H HE1  . PHE B 1 234 ? 10.830  39.907  52.503 1.00 31.88 ?  200  PHE B HE1  1 
ATOM   8653  H HE2  . PHE B 1 234 ? 14.392  38.288  51.888 1.00 32.01 ?  200  PHE B HE2  1 
ATOM   8654  H HZ   . PHE B 1 234 ? 12.319  38.203  52.819 1.00 26.58 ?  200  PHE B HZ   1 
ATOM   8655  N N    . SER B 1 235 ? 13.928  44.451  47.616 1.00 15.36 ?  201  SER B N    1 
ATOM   8656  C CA   . SER B 1 235 ? 14.217  45.792  47.104 1.00 16.08 ?  201  SER B CA   1 
ATOM   8657  C C    . SER B 1 235 ? 12.984  46.394  46.457 1.00 14.91 ?  201  SER B C    1 
ATOM   8658  O O    . SER B 1 235 ? 12.654  47.574  46.675 1.00 16.50 ?  201  SER B O    1 
ATOM   8659  C CB   . SER B 1 235 ? 15.338  45.653  46.065 1.00 19.64 ?  201  SER B CB   1 
ATOM   8660  O OG   . SER B 1 235 ? 15.680  46.915  45.536 1.00 31.31 ?  201  SER B OG   1 
ATOM   8661  H H    . SER B 1 235 ? 14.384  43.823  47.244 1.00 18.43 ?  201  SER B H    1 
ATOM   8662  H HA   . SER B 1 235 ? 14.496  46.381  47.822 1.00 19.30 ?  201  SER B HA   1 
ATOM   8663  H HB2  . SER B 1 235 ? 16.118  45.265  46.491 1.00 23.56 ?  201  SER B HB2  1 
ATOM   8664  H HB3  . SER B 1 235 ? 15.033  45.079  45.345 1.00 23.56 ?  201  SER B HB3  1 
ATOM   8665  H HG   . SER B 1 235 ? 16.306  46.834  44.981 1.00 37.58 ?  201  SER B HG   1 
ATOM   8666  N N    . MET B 1 236 ? 12.236  45.581  45.704 1.00 15.07 ?  202  MET B N    1 
ATOM   8667  C CA   . MET B 1 236 ? 11.030  46.036  45.040 1.00 14.81 ?  202  MET B CA   1 
ATOM   8668  C C    . MET B 1 236 ? 9.957   46.391  46.069 1.00 14.29 ?  202  MET B C    1 
ATOM   8669  O O    . MET B 1 236 ? 9.264   47.415  45.917 1.00 15.08 ?  202  MET B O    1 
ATOM   8670  C CB   . MET B 1 236 ? 10.625  44.837  44.194 1.00 15.94 ?  202  MET B CB   1 
ATOM   8671  C CG   . MET B 1 236 ? 11.223  44.833  42.821 1.00 14.14 ?  202  MET B CG   1 
ATOM   8672  S SD   . MET B 1 236 ? 11.008  43.237  41.994 1.00 15.25 ?  202  MET B SD   1 
ATOM   8673  C CE   . MET B 1 236 ? 9.467   43.588  41.171 1.00 16.88 ?  202  MET B CE   1 
ATOM   8674  H H    . MET B 1 236 ? 12.413  44.751  45.564 1.00 18.09 ?  202  MET B H    1 
ATOM   8675  H HA   . MET B 1 236 ? 11.157  46.827  44.494 1.00 17.78 ?  202  MET B HA   1 
ATOM   8676  H HB2  . MET B 1 236 ? 10.913  44.027  44.644 1.00 19.13 ?  202  MET B HB2  1 
ATOM   8677  H HB3  . MET B 1 236 ? 9.660   44.837  44.096 1.00 19.13 ?  202  MET B HB3  1 
ATOM   8678  H HG2  . MET B 1 236 ? 10.790  45.514  42.283 1.00 16.97 ?  202  MET B HG2  1 
ATOM   8679  H HG3  . MET B 1 236 ? 12.173  45.015  42.887 1.00 16.97 ?  202  MET B HG3  1 
ATOM   8680  H HE1  . MET B 1 236 ? 9.210   42.817  40.641 1.00 20.25 ?  202  MET B HE1  1 
ATOM   8681  H HE2  . MET B 1 236 ? 8.787   43.772  41.837 1.00 20.25 ?  202  MET B HE2  1 
ATOM   8682  H HE3  . MET B 1 236 ? 9.585   44.360  40.596 1.00 20.25 ?  202  MET B HE3  1 
ATOM   8683  N N    . MET B 1 237 ? 9.803   45.597  47.131 1.00 13.74 ?  203  MET B N    1 
ATOM   8684  C CA   . MET B 1 237 ? 8.812   45.908  48.153 1.00 13.71 ?  203  MET B CA   1 
ATOM   8685  C C    . MET B 1 237 ? 9.172   47.165  48.915 1.00 15.23 ?  203  MET B C    1 
ATOM   8686  O O    . MET B 1 237 ? 8.277   47.954  49.249 1.00 15.08 ?  203  MET B O    1 
ATOM   8687  C CB   . MET B 1 237 ? 8.494   44.757  49.083 1.00 12.69 ?  203  MET B CB   1 
ATOM   8688  C CG   . MET B 1 237 ? 8.033   43.451  48.391 1.00 13.54 ?  203  MET B CG   1 
ATOM   8689  S SD   . MET B 1 237 ? 6.457   43.664  47.489 1.00 14.20 ?  203  MET B SD   1 
ATOM   8690  C CE   . MET B 1 237 ? 7.083   43.954  45.834 1.00 16.20 ?  203  MET B CE   1 
ATOM   8691  H H    . MET B 1 237 ? 10.256  44.881  47.279 1.00 16.49 ?  203  MET B H    1 
ATOM   8692  H HA   . MET B 1 237 ? 7.981   46.053  47.675 1.00 16.45 ?  203  MET B HA   1 
ATOM   8693  H HB2  . MET B 1 237 ? 9.291   44.547  49.594 1.00 15.22 ?  203  MET B HB2  1 
ATOM   8694  H HB3  . MET B 1 237 ? 7.781   45.034  49.679 1.00 15.22 ?  203  MET B HB3  1 
ATOM   8695  H HG2  . MET B 1 237 ? 8.710   43.172  47.755 1.00 16.25 ?  203  MET B HG2  1 
ATOM   8696  H HG3  . MET B 1 237 ? 7.906   42.763  49.063 1.00 16.25 ?  203  MET B HG3  1 
ATOM   8697  H HE1  . MET B 1 237 ? 6.340   43.956  45.211 1.00 19.44 ?  203  MET B HE1  1 
ATOM   8698  H HE2  . MET B 1 237 ? 7.534   44.813  45.814 1.00 19.44 ?  203  MET B HE2  1 
ATOM   8699  H HE3  . MET B 1 237 ? 7.707   43.248  45.604 1.00 19.44 ?  203  MET B HE3  1 
ATOM   8700  N N    . SER B 1 238 ? 10.466  47.375  49.173 1.00 15.28 ?  204  SER B N    1 
ATOM   8701  C CA   . SER B 1 238 ? 10.887  48.632  49.809 1.00 15.74 ?  204  SER B CA   1 
ATOM   8702  C C    . SER B 1 238 ? 10.577  49.815  48.928 1.00 15.65 ?  204  SER B C    1 
ATOM   8703  O O    . SER B 1 238 ? 10.114  50.853  49.432 1.00 16.19 ?  204  SER B O    1 
ATOM   8704  C CB   . SER B 1 238 ? 12.361  48.608  50.171 1.00 17.87 ?  204  SER B CB   1 
ATOM   8705  O OG   . SER B 1 238 ? 12.604  47.591  51.097 1.00 24.50 ?  204  SER B OG   1 
ATOM   8706  H H    . SER B 1 238 ? 11.103  46.825  48.998 1.00 18.34 ?  204  SER B H    1 
ATOM   8707  H HA   . SER B 1 238 ? 10.394  48.724  50.639 1.00 18.89 ?  204  SER B HA   1 
ATOM   8708  H HB2  . SER B 1 238 ? 12.885  48.444  49.371 1.00 21.44 ?  204  SER B HB2  1 
ATOM   8709  H HB3  . SER B 1 238 ? 12.609  49.461  50.560 1.00 21.44 ?  204  SER B HB3  1 
ATOM   8710  H HG   . SER B 1 238 ? 13.426  47.546  51.267 1.00 29.40 ?  204  SER B HG   1 
ATOM   8711  N N    . ARG B 1 239 ? 10.786  49.688  47.613 1.00 15.09 ?  205  ARG B N    1 
ATOM   8712  C CA   . ARG B 1 239 ? 10.467  50.783  46.703 1.00 16.55 ?  205  ARG B CA   1 
ATOM   8713  C C    . ARG B 1 239 ? 8.987   51.099  46.728 1.00 16.48 ?  205  ARG B C    1 
ATOM   8714  O O    . ARG B 1 239 ? 8.581   52.273  46.772 1.00 18.08 ?  205  ARG B O    1 
ATOM   8715  C CB   . ARG B 1 239 ? 10.880  50.437  45.274 1.00 21.67 ?  205  ARG B CB   1 
ATOM   8716  C CG   . ARG B 1 239 ? 12.374  50.460  45.027 1.00 22.63 ?  205  ARG B CG   1 
ATOM   8717  C CD   . ARG B 1 239 ? 12.851  51.809  44.528 1.00 26.07 ?  205  ARG B CD   1 
ATOM   8718  N NE   . ARG B 1 239 ? 12.255  52.219  43.260 1.00 21.44 ?  205  ARG B NE   1 
ATOM   8719  C CZ   . ARG B 1 239 ? 12.718  51.880  42.060 1.00 22.26 ?  205  ARG B CZ   1 
ATOM   8720  N NH1  . ARG B 1 239 ? 13.766  51.097  41.921 1.00 23.10 ?  205  ARG B NH1  1 
ATOM   8721  N NH2  . ARG B 1 239 ? 12.089  52.316  40.970 1.00 23.57 ?  205  ARG B NH2  1 
ATOM   8722  H H    . ARG B 1 239 ? 11.108  48.988  47.232 1.00 18.10 ?  205  ARG B H    1 
ATOM   8723  H HA   . ARG B 1 239 ? 10.969  51.561  46.991 1.00 19.86 ?  205  ARG B HA   1 
ATOM   8724  H HB2  . ARG B 1 239 ? 10.563  49.543  45.069 1.00 26.00 ?  205  ARG B HB2  1 
ATOM   8725  H HB3  . ARG B 1 239 ? 10.474  51.079  44.671 1.00 26.00 ?  205  ARG B HB3  1 
ATOM   8726  H HG2  . ARG B 1 239 ? 12.837  50.264  45.857 1.00 27.16 ?  205  ARG B HG2  1 
ATOM   8727  H HG3  . ARG B 1 239 ? 12.597  49.794  44.358 1.00 27.16 ?  205  ARG B HG3  1 
ATOM   8728  H HD2  . ARG B 1 239 ? 12.628  52.483  45.190 1.00 31.28 ?  205  ARG B HD2  1 
ATOM   8729  H HD3  . ARG B 1 239 ? 13.813  51.772  44.403 1.00 31.28 ?  205  ARG B HD3  1 
ATOM   8730  H HE   . ARG B 1 239 ? 11.553  52.716  43.291 1.00 25.73 ?  205  ARG B HE   1 
ATOM   8731  H HH11 . ARG B 1 239 ? 14.170  50.791  42.616 1.00 27.72 ?  205  ARG B HH11 1 
ATOM   8732  H HH12 . ARG B 1 239 ? 14.048  50.892  41.134 1.00 27.72 ?  205  ARG B HH12 1 
ATOM   8733  H HH21 . ARG B 1 239 ? 11.390  52.811  41.046 1.00 28.29 ?  205  ARG B HH21 1 
ATOM   8734  H HH22 . ARG B 1 239 ? 12.382  52.101  40.190 1.00 28.29 ?  205  ARG B HH22 1 
ATOM   8735  N N    . LEU B 1 240 ? 8.144   50.071  46.656 1.00 16.73 ?  206  LEU B N    1 
ATOM   8736  C CA   . LEU B 1 240 ? 6.712   50.312  46.631 1.00 14.43 ?  206  LEU B CA   1 
ATOM   8737  C C    . LEU B 1 240 ? 6.228   50.907  47.941 1.00 14.39 ?  206  LEU B C    1 
ATOM   8738  O O    . LEU B 1 240 ? 5.348   51.766  47.947 1.00 15.98 ?  206  LEU B O    1 
ATOM   8739  C CB   . LEU B 1 240 ? 5.960   48.997  46.407 1.00 20.62 ?  206  LEU B CB   1 
ATOM   8740  C CG   . LEU B 1 240 ? 5.657   48.518  45.008 1.00 23.72 ?  206  LEU B CG   1 
ATOM   8741  C CD1  . LEU B 1 240 ? 4.684   47.331  45.174 1.00 20.48 ?  206  LEU B CD1  1 
ATOM   8742  C CD2  . LEU B 1 240 ? 5.097   49.568  44.098 1.00 19.63 ?  206  LEU B CD2  1 
ATOM   8743  H H    A LEU B 1 240 ? 8.374   49.243  46.622 0.27 20.07 ?  206  LEU B H    1 
ATOM   8744  H H    B LEU B 1 240 ? 8.374   49.243  46.622 0.73 20.07 ?  206  LEU B H    1 
ATOM   8745  H HA   . LEU B 1 240 ? 6.528   50.925  45.903 1.00 17.32 ?  206  LEU B HA   1 
ATOM   8746  H HB2  . LEU B 1 240 ? 6.484   48.295  46.823 1.00 24.74 ?  206  LEU B HB2  1 
ATOM   8747  H HB3  . LEU B 1 240 ? 5.103   49.080  46.853 1.00 24.74 ?  206  LEU B HB3  1 
ATOM   8748  H HG   . LEU B 1 240 ? 6.479   48.259  44.562 1.00 28.46 ?  206  LEU B HG   1 
ATOM   8749  H HD11 . LEU B 1 240 ? 4.420   47.015  44.296 1.00 24.57 ?  206  LEU B HD11 1 
ATOM   8750  H HD12 . LEU B 1 240 ? 5.132   46.621  45.661 1.00 24.57 ?  206  LEU B HD12 1 
ATOM   8751  H HD13 . LEU B 1 240 ? 3.904   47.629  45.667 1.00 24.57 ?  206  LEU B HD13 1 
ATOM   8752  H HD21 . LEU B 1 240 ? 4.781   49.144  43.284 1.00 23.56 ?  206  LEU B HD21 1 
ATOM   8753  H HD22 . LEU B 1 240 ? 4.361   50.014  44.545 1.00 23.56 ?  206  LEU B HD22 1 
ATOM   8754  H HD23 . LEU B 1 240 ? 5.794   50.209  43.888 1.00 23.56 ?  206  LEU B HD23 1 
ATOM   8755  N N    . LYS B 1 241 ? 6.784   50.466  49.072 1.00 15.22 ?  207  LYS B N    1 
ATOM   8756  C CA   . LYS B 1 241 ? 6.370   50.990  50.357 1.00 15.98 ?  207  LYS B CA   1 
ATOM   8757  C C    . LYS B 1 241 ? 6.514   52.496  50.372 1.00 17.10 ?  207  LYS B C    1 
ATOM   8758  O O    . LYS B 1 241 ? 5.639   53.204  50.887 1.00 17.23 ?  207  LYS B O    1 
ATOM   8759  C CB   . LYS B 1 241 ? 7.196   50.358  51.469 1.00 15.54 ?  207  LYS B CB   1 
ATOM   8760  C CG   . LYS B 1 241 ? 6.844   50.849  52.859 1.00 15.58 ?  207  LYS B CG   1 
ATOM   8761  C CD   . LYS B 1 241 ? 7.602   50.133  53.921 1.00 16.94 ?  207  LYS B CD   1 
ATOM   8762  C CE   . LYS B 1 241 ? 7.165   50.564  55.332 1.00 19.31 ?  207  LYS B CE   1 
ATOM   8763  N NZ   . LYS B 1 241 ? 7.972   49.915  56.377 1.00 21.83 ?  207  LYS B NZ   1 
ATOM   8764  H H    . LYS B 1 241 ? 7.400   49.867  49.115 1.00 18.26 ?  207  LYS B H    1 
ATOM   8765  H HA   . LYS B 1 241 ? 5.440   50.764  50.520 1.00 19.18 ?  207  LYS B HA   1 
ATOM   8766  H HB2  . LYS B 1 241 ? 7.055   49.398  51.452 1.00 18.65 ?  207  LYS B HB2  1 
ATOM   8767  H HB3  . LYS B 1 241 ? 8.132   50.559  51.313 1.00 18.65 ?  207  LYS B HB3  1 
ATOM   8768  H HG2  . LYS B 1 241 ? 7.054   51.794  52.924 1.00 18.70 ?  207  LYS B HG2  1 
ATOM   8769  H HG3  . LYS B 1 241 ? 5.898   50.708  53.016 1.00 18.70 ?  207  LYS B HG3  1 
ATOM   8770  H HD2  . LYS B 1 241 ? 7.448   49.179  53.835 1.00 20.33 ?  207  LYS B HD2  1 
ATOM   8771  H HD3  . LYS B 1 241 ? 8.548   50.326  53.825 1.00 20.33 ?  207  LYS B HD3  1 
ATOM   8772  H HE2  . LYS B 1 241 ? 7.270   51.525  55.419 1.00 23.17 ?  207  LYS B HE2  1 
ATOM   8773  H HE3  . LYS B 1 241 ? 6.236   50.318  55.468 1.00 23.17 ?  207  LYS B HE3  1 
ATOM   8774  H HZ1  . LYS B 1 241 ? 7.682   50.160  57.182 1.00 26.19 ?  207  LYS B HZ1  1 
ATOM   8775  H HZ2  . LYS B 1 241 ? 7.910   49.031  56.305 1.00 26.19 ?  207  LYS B HZ2  1 
ATOM   8776  H HZ3  . LYS B 1 241 ? 8.826   50.153  56.294 1.00 26.19 ?  207  LYS B HZ3  1 
ATOM   8777  N N    . GLU B 1 242 ? 7.583   52.992  49.775 1.00 14.62 ?  208  GLU B N    1 
ATOM   8778  C CA   . GLU B 1 242 ? 7.811   54.436  49.738 1.00 15.87 ?  208  GLU B CA   1 
ATOM   8779  C C    . GLU B 1 242 ? 6.946   55.112  48.680 1.00 15.53 ?  208  GLU B C    1 
ATOM   8780  O O    . GLU B 1 242 ? 6.289   56.133  48.969 1.00 18.38 ?  208  GLU B O    1 
ATOM   8781  C CB   . GLU B 1 242 ? 9.296   54.719  49.485 1.00 19.20 ?  208  GLU B CB   1 
ATOM   8782  C CG   . GLU B 1 242 ? 10.221  54.249  50.592 1.00 28.98 ?  208  GLU B CG   1 
ATOM   8783  C CD   . GLU B 1 242 ? 9.827   54.735  51.982 1.00 45.66 ?  208  GLU B CD   1 
ATOM   8784  O OE1  . GLU B 1 242 ? 9.541   53.867  52.880 1.00 30.99 ?  208  GLU B OE1  1 
ATOM   8785  O OE2  . GLU B 1 242 ? 9.755   55.975  52.152 1.00 40.28 ?  208  GLU B OE2  1 
ATOM   8786  H H    . GLU B 1 242 ? 8.190   52.524  49.386 1.00 17.54 ?  208  GLU B H    1 
ATOM   8787  H HA   . GLU B 1 242 ? 7.572   54.815  50.599 1.00 19.04 ?  208  GLU B HA   1 
ATOM   8788  H HB2  . GLU B 1 242 ? 9.563   54.268  48.669 1.00 23.05 ?  208  GLU B HB2  1 
ATOM   8789  H HB3  . GLU B 1 242 ? 9.417   55.677  49.389 1.00 23.05 ?  208  GLU B HB3  1 
ATOM   8790  H HG2  . GLU B 1 242 ? 10.219  53.279  50.607 1.00 34.77 ?  208  GLU B HG2  1 
ATOM   8791  H HG3  . GLU B 1 242 ? 11.116  54.576  50.409 1.00 34.77 ?  208  GLU B HG3  1 
ATOM   8792  N N    . SER B 1 243 ? 6.906   54.578  47.443 1.00 14.90 ?  209  SER B N    1 
ATOM   8793  C CA   . SER B 1 243 ? 6.197   55.296  46.378 1.00 14.62 ?  209  SER B CA   1 
ATOM   8794  C C    . SER B 1 243 ? 4.689   55.301  46.610 1.00 15.71 ?  209  SER B C    1 
ATOM   8795  O O    . SER B 1 243 ? 3.981   56.241  46.184 1.00 17.92 ?  209  SER B O    1 
ATOM   8796  C CB   . SER B 1 243 ? 6.439   54.739  44.981 1.00 17.70 ?  209  SER B CB   1 
ATOM   8797  O OG   . SER B 1 243 ? 6.173   53.370  44.946 1.00 20.88 ?  209  SER B OG   1 
ATOM   8798  H H    . SER B 1 243 ? 7.268   53.833  47.209 1.00 17.89 ?  209  SER B H    1 
ATOM   8799  H HA   . SER B 1 243 ? 6.563   56.194  46.398 1.00 17.55 ?  209  SER B HA   1 
ATOM   8800  H HB2  . SER B 1 243 ? 5.854   55.192  44.353 1.00 21.24 ?  209  SER B HB2  1 
ATOM   8801  H HB3  . SER B 1 243 ? 7.366   54.887  44.737 1.00 21.24 ?  209  SER B HB3  1 
ATOM   8802  H HG   . SER B 1 243 ? 6.315   53.069  44.174 1.00 25.06 ?  209  SER B HG   1 
ATOM   8803  N N    . LEU B 1 244 ? 4.150   54.267  47.272 1.00 14.92 ?  210  LEU B N    1 
ATOM   8804  C CA   . LEU B 1 244 ? 2.719   54.154  47.518 1.00 13.19 ?  210  LEU B CA   1 
ATOM   8805  C C    . LEU B 1 244 ? 2.335   54.549  48.940 1.00 15.05 ?  210  LEU B C    1 
ATOM   8806  O O    . LEU B 1 244 ? 1.278   54.161  49.453 1.00 15.16 ?  210  LEU B O    1 
ATOM   8807  C CB   . LEU B 1 244 ? 2.251   52.730  47.218 1.00 13.78 ?  210  LEU B CB   1 
ATOM   8808  C CG   . LEU B 1 244 ? 2.518   52.308  45.786 1.00 15.96 ?  210  LEU B CG   1 
ATOM   8809  C CD1  . LEU B 1 244 ? 1.774   50.980  45.543 1.00 16.87 ?  210  LEU B CD1  1 
ATOM   8810  C CD2  . LEU B 1 244 ? 2.087   53.294  44.761 1.00 16.39 ?  210  LEU B CD2  1 
ATOM   8811  H H    . LEU B 1 244 ? 4.608   53.612  47.591 1.00 17.91 ?  210  LEU B H    1 
ATOM   8812  H HA   . LEU B 1 244 ? 2.258   54.760  46.917 1.00 15.83 ?  210  LEU B HA   1 
ATOM   8813  H HB2  . LEU B 1 244 ? 2.719   52.115  47.804 1.00 16.54 ?  210  LEU B HB2  1 
ATOM   8814  H HB3  . LEU B 1 244 ? 1.295   52.674  47.375 1.00 16.54 ?  210  LEU B HB3  1 
ATOM   8815  H HG   . LEU B 1 244 ? 3.478   52.226  45.679 1.00 19.15 ?  210  LEU B HG   1 
ATOM   8816  H HD11 . LEU B 1 244 ? 1.937   50.689  44.633 1.00 20.24 ?  210  LEU B HD11 1 
ATOM   8817  H HD12 . LEU B 1 244 ? 2.104   50.315  46.167 1.00 20.24 ?  210  LEU B HD12 1 
ATOM   8818  H HD13 . LEU B 1 244 ? 0.824   51.120  45.681 1.00 20.24 ?  210  LEU B HD13 1 
ATOM   8819  H HD21 . LEU B 1 244 ? 2.171   52.891  43.882 1.00 19.67 ?  210  LEU B HD21 1 
ATOM   8820  H HD22 . LEU B 1 244 ? 1.163   53.538  44.926 1.00 19.67 ?  210  LEU B HD22 1 
ATOM   8821  H HD23 . LEU B 1 244 ? 2.653   54.079  44.820 1.00 19.67 ?  210  LEU B HD23 1 
ATOM   8822  N N    . SER B 1 245 ? 3.159   55.413  49.580 1.00 15.00 ?  211  SER B N    1 
ATOM   8823  C CA   . SER B 1 245 ? 2.899   55.805  50.960 1.00 16.82 ?  211  SER B CA   1 
ATOM   8824  C C    . SER B 1 245 ? 1.640   56.635  51.123 1.00 16.16 ?  211  SER B C    1 
ATOM   8825  O O    . SER B 1 245 ? 1.150   56.756  52.250 1.00 20.14 ?  211  SER B O    1 
ATOM   8826  C CB   . SER B 1 245 ? 4.101   56.550  51.565 1.00 18.67 ?  211  SER B CB   1 
ATOM   8827  O OG   . SER B 1 245 ? 4.377   57.728  50.835 1.00 20.38 ?  211  SER B OG   1 
ATOM   8828  H H    . SER B 1 245 ? 3.859   55.773  49.232 1.00 18.00 ?  211  SER B H    1 
ATOM   8829  H HA   . SER B 1 245 ? 2.776   54.989  51.470 1.00 20.18 ?  211  SER B HA   1 
ATOM   8830  H HB2  . SER B 1 245 ? 3.898   56.787  52.483 1.00 22.40 ?  211  SER B HB2  1 
ATOM   8831  H HB3  . SER B 1 245 ? 4.879   55.971  51.536 1.00 22.40 ?  211  SER B HB3  1 
ATOM   8832  H HG   . SER B 1 245 ? 5.122   58.040  51.064 1.00 24.46 ?  211  SER B HG   1 
ATOM   8833  N N    . ASN B 1 246 ? 1.104   57.187  50.046 1.00 14.94 ?  212  ASN B N    1 
ATOM   8834  C CA   . ASN B 1 246 ? -0.172  57.890  50.085 1.00 17.73 ?  212  ASN B CA   1 
ATOM   8835  C C    . ASN B 1 246 ? -1.312  57.056  49.541 1.00 16.26 ?  212  ASN B C    1 
ATOM   8836  O O    . ASN B 1 246 ? -2.364  57.581  49.178 1.00 16.98 ?  212  ASN B O    1 
ATOM   8837  C CB   . ASN B 1 246 ? -0.067  59.228  49.341 1.00 17.47 ?  212  ASN B CB   1 
ATOM   8838  C CG   . ASN B 1 246 ? 0.915   60.166  49.990 1.00 22.91 ?  212  ASN B CG   1 
ATOM   8839  O OD1  . ASN B 1 246 ? 0.882   60.354  51.202 1.00 23.50 ?  212  ASN B OD1  1 
ATOM   8840  N ND2  . ASN B 1 246 ? 1.829   60.705  49.199 1.00 29.13 ?  212  ASN B ND2  1 
ATOM   8841  H H    . ASN B 1 246 ? 1.466   57.168  49.266 1.00 17.93 ?  212  ASN B H    1 
ATOM   8842  H HA   . ASN B 1 246 ? -0.382  58.090  51.011 1.00 21.28 ?  212  ASN B HA   1 
ATOM   8843  H HB2  . ASN B 1 246 ? 0.229   59.064  48.432 1.00 20.97 ?  212  ASN B HB2  1 
ATOM   8844  H HB3  . ASN B 1 246 ? -0.936  59.657  49.335 1.00 20.97 ?  212  ASN B HB3  1 
ATOM   8845  H HD21 . ASN B 1 246 ? 2.412   61.248  49.522 1.00 34.96 ?  212  ASN B HD21 1 
ATOM   8846  H HD22 . ASN B 1 246 ? 1.839   60.513  48.361 1.00 34.96 ?  212  ASN B HD22 1 
ATOM   8847  N N    . ASN B 1 247 ? -1.098  55.738  49.461 1.00 14.62 ?  213  ASN B N    1 
ATOM   8848  C CA   . ASN B 1 247 ? -2.051  54.779  48.888 1.00 14.09 ?  213  ASN B CA   1 
ATOM   8849  C C    . ASN B 1 247 ? -2.065  53.553  49.783 1.00 13.97 ?  213  ASN B C    1 
ATOM   8850  O O    . ASN B 1 247 ? -1.438  53.541  50.847 1.00 14.78 ?  213  ASN B O    1 
ATOM   8851  C CB   . ASN B 1 247 ? -1.609  54.451  47.461 1.00 12.80 ?  213  ASN B CB   1 
ATOM   8852  C CG   . ASN B 1 247 ? -1.744  55.616  46.518 1.00 14.50 ?  213  ASN B CG   1 
ATOM   8853  O OD1  . ASN B 1 247 ? -0.765  56.242  46.126 1.00 16.17 ?  213  ASN B OD1  1 
ATOM   8854  N ND2  . ASN B 1 247 ? -2.970  55.869  46.108 1.00 14.01 ?  213  ASN B ND2  1 
ATOM   8855  H H    . ASN B 1 247 ? -0.379  55.359  49.743 1.00 17.55 ?  213  ASN B H    1 
ATOM   8856  H HA   . ASN B 1 247 ? -2.946  55.153  48.877 1.00 16.91 ?  213  ASN B HA   1 
ATOM   8857  H HB2  . ASN B 1 247 ? -0.677  54.184  47.474 1.00 15.36 ?  213  ASN B HB2  1 
ATOM   8858  H HB3  . ASN B 1 247 ? -2.157  53.727  47.120 1.00 15.36 ?  213  ASN B HB3  1 
ATOM   8859  H HD21 . ASN B 1 247 ? -3.117  56.522  45.568 1.00 16.81 ?  213  ASN B HD21 1 
ATOM   8860  H HD22 . ASN B 1 247 ? -3.624  55.381  46.380 1.00 16.81 ?  213  ASN B HD22 1 
ATOM   8861  N N    . LEU B 1 248 ? -2.753  52.504  49.339 1.00 13.12 ?  214  LEU B N    1 
ATOM   8862  C CA   . LEU B 1 248 ? -2.813  51.238  50.077 1.00 13.61 ?  214  LEU B CA   1 
ATOM   8863  C C    . LEU B 1 248 ? -2.044  50.129  49.365 1.00 12.20 ?  214  LEU B C    1 
ATOM   8864  O O    . LEU B 1 248 ? -2.100  50.001  48.145 1.00 13.04 ?  214  LEU B O    1 
ATOM   8865  C CB   . LEU B 1 248 ? -4.253  50.787  50.279 1.00 13.64 ?  214  LEU B CB   1 
ATOM   8866  C CG   . LEU B 1 248 ? -5.114  51.693  51.173 1.00 13.48 ?  214  LEU B CG   1 
ATOM   8867  C CD1  . LEU B 1 248 ? -6.567  51.243  51.118 1.00 14.50 ?  214  LEU B CD1  1 
ATOM   8868  C CD2  . LEU B 1 248 ? -4.602  51.707  52.598 1.00 15.73 ?  214  LEU B CD2  1 
ATOM   8869  H H    . LEU B 1 248 ? -3.200  52.499  48.604 1.00 15.74 ?  214  LEU B H    1 
ATOM   8870  H HA   . LEU B 1 248 ? -2.394  51.379  50.940 1.00 16.33 ?  214  LEU B HA   1 
ATOM   8871  H HB2  . LEU B 1 248 ? -4.683  50.746  49.410 1.00 16.37 ?  214  LEU B HB2  1 
ATOM   8872  H HB3  . LEU B 1 248 ? -4.242  49.907  50.685 1.00 16.37 ?  214  LEU B HB3  1 
ATOM   8873  H HG   . LEU B 1 248 ? -5.061  52.605  50.847 1.00 16.17 ?  214  LEU B HG   1 
ATOM   8874  H HD11 . LEU B 1 248 ? -7.090  51.788  51.726 1.00 17.41 ?  214  LEU B HD11 1 
ATOM   8875  H HD12 . LEU B 1 248 ? -6.896  51.349  50.211 1.00 17.41 ?  214  LEU B HD12 1 
ATOM   8876  H HD13 . LEU B 1 248 ? -6.619  50.311  51.381 1.00 17.41 ?  214  LEU B HD13 1 
ATOM   8877  H HD21 . LEU B 1 248 ? -5.192  52.253  53.141 1.00 18.87 ?  214  LEU B HD21 1 
ATOM   8878  H HD22 . LEU B 1 248 ? -4.588  50.798  52.937 1.00 18.87 ?  214  LEU B HD22 1 
ATOM   8879  H HD23 . LEU B 1 248 ? -3.706  52.077  52.609 1.00 18.87 ?  214  LEU B HD23 1 
ATOM   8880  N N    . ILE B 1 249 ? -1.342  49.323  50.162 1.00 12.05 ?  215  ILE B N    1 
ATOM   8881  C CA   . ILE B 1 249 ? -0.690  48.105  49.661 1.00 11.94 ?  215  ILE B CA   1 
ATOM   8882  C C    . ILE B 1 249 ? -1.174  46.934  50.501 1.00 13.16 ?  215  ILE B C    1 
ATOM   8883  O O    . ILE B 1 249 ? -0.904  46.879  51.710 1.00 13.82 ?  215  ILE B O    1 
ATOM   8884  C CB   . ILE B 1 249 ? 0.847   48.191  49.735 1.00 13.23 ?  215  ILE B CB   1 
ATOM   8885  C CG1  . ILE B 1 249 ? 1.387   49.566  49.278 1.00 14.56 ?  215  ILE B CG1  1 
ATOM   8886  C CG2  . ILE B 1 249 ? 1.457   47.039  48.920 1.00 15.32 ?  215  ILE B CG2  1 
ATOM   8887  C CD1  . ILE B 1 249 ? 2.844   49.708  49.561 1.00 16.81 ?  215  ILE B CD1  1 
ATOM   8888  H H    . ILE B 1 249 ? -1.228  49.459  51.003 1.00 14.45 ?  215  ILE B H    1 
ATOM   8889  H HA   . ILE B 1 249 ? -0.963  47.967  48.740 1.00 14.33 ?  215  ILE B HA   1 
ATOM   8890  H HB   . ILE B 1 249 ? 1.112   48.102  50.664 1.00 15.87 ?  215  ILE B HB   1 
ATOM   8891  H HG12 . ILE B 1 249 ? 1.252   49.662  48.322 1.00 17.47 ?  215  ILE B HG12 1 
ATOM   8892  H HG13 . ILE B 1 249 ? 0.915   50.269  49.752 1.00 17.47 ?  215  ILE B HG13 1 
ATOM   8893  H HG21 . ILE B 1 249 ? 2.419   47.039  49.043 1.00 18.39 ?  215  ILE B HG21 1 
ATOM   8894  H HG22 . ILE B 1 249 ? 1.084   46.199  49.232 1.00 18.39 ?  215  ILE B HG22 1 
ATOM   8895  H HG23 . ILE B 1 249 ? 1.243   47.167  47.983 1.00 18.39 ?  215  ILE B HG23 1 
ATOM   8896  H HD11 . ILE B 1 249 ? 3.119   50.615  49.355 1.00 20.18 ?  215  ILE B HD11 1 
ATOM   8897  H HD12 . ILE B 1 249 ? 3.004   49.519  50.499 1.00 20.18 ?  215  ILE B HD12 1 
ATOM   8898  H HD13 . ILE B 1 249 ? 3.336   49.080  49.008 1.00 20.18 ?  215  ILE B HD13 1 
ATOM   8899  N N    . LEU B 1 250 ? -1.935  46.028  49.887 1.00 11.75 ?  216  LEU B N    1 
ATOM   8900  C CA   . LEU B 1 250 ? -2.402  44.816  50.552 1.00 11.89 ?  216  LEU B CA   1 
ATOM   8901  C C    . LEU B 1 250 ? -1.640  43.653  49.937 1.00 13.33 ?  216  LEU B C    1 
ATOM   8902  O O    . LEU B 1 250 ? -1.450  43.619  48.722 1.00 15.84 ?  216  LEU B O    1 
ATOM   8903  C CB   . LEU B 1 250 ? -3.883  44.678  50.285 1.00 13.97 ?  216  LEU B CB   1 
ATOM   8904  C CG   . LEU B 1 250 ? -4.651  43.538  50.980 1.00 16.78 ?  216  LEU B CG   1 
ATOM   8905  C CD1  . LEU B 1 250 ? -4.763  43.749  52.427 1.00 18.57 ?  216  LEU B CD1  1 
ATOM   8906  C CD2  . LEU B 1 250 ? -6.019  43.416  50.383 1.00 18.64 ?  216  LEU B CD2  1 
ATOM   8907  H H    . LEU B 1 250 ? -2.197  46.096  49.071 1.00 14.10 ?  216  LEU B H    1 
ATOM   8908  H HA   . LEU B 1 250 ? -2.253  44.819  51.511 1.00 14.26 ?  216  LEU B HA   1 
ATOM   8909  H HB2  . LEU B 1 250 ? -4.308  45.506  50.559 1.00 16.76 ?  216  LEU B HB2  1 
ATOM   8910  H HB3  . LEU B 1 250 ? -3.997  44.547  49.330 1.00 16.76 ?  216  LEU B HB3  1 
ATOM   8911  H HG   . LEU B 1 250 ? -4.157  42.715  50.845 1.00 20.13 ?  216  LEU B HG   1 
ATOM   8912  H HD11 . LEU B 1 250 ? -5.147  42.956  52.833 1.00 22.28 ?  216  LEU B HD11 1 
ATOM   8913  H HD12 . LEU B 1 250 ? -3.879  43.912  52.792 1.00 22.28 ?  216  LEU B HD12 1 
ATOM   8914  H HD13 . LEU B 1 250 ? -5.335  44.515  52.592 1.00 22.28 ?  216  LEU B HD13 1 
ATOM   8915  H HD21 . LEU B 1 250 ? -6.483  42.676  50.805 1.00 22.37 ?  216  LEU B HD21 1 
ATOM   8916  H HD22 . LEU B 1 250 ? -6.505  44.242  50.536 1.00 22.37 ?  216  LEU B HD22 1 
ATOM   8917  H HD23 . LEU B 1 250 ? -5.935  43.253  49.431 1.00 22.37 ?  216  LEU B HD23 1 
ATOM   8918  N N    . ALA B 1 251 ? -1.151  42.692  50.749 1.00 12.38 ?  217  ALA B N    1 
ATOM   8919  C CA   . ALA B 1 251 ? -0.377  41.589  50.199 1.00 13.03 ?  217  ALA B CA   1 
ATOM   8920  C C    . ALA B 1 251 ? -0.965  40.251  50.622 1.00 12.64 ?  217  ALA B C    1 
ATOM   8921  O O    . ALA B 1 251 ? -1.480  40.085  51.723 1.00 13.88 ?  217  ALA B O    1 
ATOM   8922  C CB   . ALA B 1 251 ? 1.089   41.649  50.692 1.00 13.13 ?  217  ALA B CB   1 
ATOM   8923  H H    . ALA B 1 251 ? -1.259  42.669  51.602 1.00 14.86 ?  217  ALA B H    1 
ATOM   8924  H HA   . ALA B 1 251 ? -0.408  41.642  49.231 1.00 15.63 ?  217  ALA B HA   1 
ATOM   8925  H HB1  . ALA B 1 251 ? 1.567   40.874  50.358 1.00 15.75 ?  217  ALA B HB1  1 
ATOM   8926  H HB2  . ALA B 1 251 ? 1.501   42.462  50.359 1.00 15.75 ?  217  ALA B HB2  1 
ATOM   8927  H HB3  . ALA B 1 251 ? 1.096   41.649  51.662 1.00 15.75 ?  217  ALA B HB3  1 
ATOM   8928  N N    . ASN B 1 252 ? -0.819  39.262  49.748 1.00 13.07 ?  218  ASN B N    1 
ATOM   8929  C CA   . ASN B 1 252 ? -1.122  37.846  50.053 1.00 11.68 ?  218  ASN B CA   1 
ATOM   8930  C C    . ASN B 1 252 ? 0.106   37.290  50.767 1.00 11.34 ?  218  ASN B C    1 
ATOM   8931  O O    . ASN B 1 252 ? 1.036   36.786  50.138 1.00 12.27 ?  218  ASN B O    1 
ATOM   8932  C CB   . ASN B 1 252 ? -1.436  37.132  48.742 1.00 12.32 ?  218  ASN B CB   1 
ATOM   8933  C CG   . ASN B 1 252 ? -1.854  35.681  48.933 1.00 11.21 ?  218  ASN B CG   1 
ATOM   8934  O OD1  . ASN B 1 252 ? -1.997  35.210  50.048 1.00 12.38 ?  218  ASN B OD1  1 
ATOM   8935  N ND2  . ASN B 1 252 ? -2.114  35.008  47.814 1.00 11.08 ?  218  ASN B ND2  1 
ATOM   8936  H H    . ASN B 1 252 ? -0.538  39.378  48.944 1.00 15.68 ?  218  ASN B H    1 
ATOM   8937  H HA   . ASN B 1 252 ? -1.883  37.740  50.646 1.00 14.02 ?  218  ASN B HA   1 
ATOM   8938  H HB2  . ASN B 1 252 ? -2.164  37.595  48.298 1.00 14.78 ?  218  ASN B HB2  1 
ATOM   8939  H HB3  . ASN B 1 252 ? -0.645  37.142  48.181 1.00 14.78 ?  218  ASN B HB3  1 
ATOM   8940  H HD21 . ASN B 1 252 ? -2.355  34.184  47.855 1.00 13.30 ?  218  ASN B HD21 1 
ATOM   8941  H HD22 . ASN B 1 252 ? -2.040  35.398  47.051 1.00 13.30 ?  218  ASN B HD22 1 
ATOM   8942  N N    . ILE B 1 253 ? 0.128   37.454  52.093 1.00 12.68 ?  219  ILE B N    1 
ATOM   8943  C CA   . ILE B 1 253 ? 1.346   37.208  52.874 1.00 12.35 ?  219  ILE B CA   1 
ATOM   8944  C C    . ILE B 1 253 ? 1.170   36.405  54.156 1.00 12.03 ?  219  ILE B C    1 
ATOM   8945  O O    . ILE B 1 253 ? 2.001   35.533  54.430 1.00 13.49 ?  219  ILE B O    1 
ATOM   8946  C CB   . ILE B 1 253 ? 2.130   38.523  53.114 1.00 14.37 ?  219  ILE B CB   1 
ATOM   8947  C CG1  . ILE B 1 253 ? 3.521   38.249  53.717 1.00 14.77 ?  219  ILE B CG1  1 
ATOM   8948  C CG2  . ILE B 1 253 ? 1.358   39.505  53.995 1.00 14.41 ?  219  ILE B CG2  1 
ATOM   8949  C CD1  . ILE B 1 253 ? 4.423   37.436  52.826 1.00 16.41 ?  219  ILE B CD1  1 
ATOM   8950  H H    . ILE B 1 253 ? -0.546  37.706  52.563 1.00 15.22 ?  219  ILE B H    1 
ATOM   8951  H HA   . ILE B 1 253 ? 1.864   36.600  52.323 1.00 14.82 ?  219  ILE B HA   1 
ATOM   8952  H HB   . ILE B 1 253 ? 2.245   38.932  52.242 1.00 17.25 ?  219  ILE B HB   1 
ATOM   8953  H HG12 . ILE B 1 253 ? 3.960   39.097  53.886 1.00 17.72 ?  219  ILE B HG12 1 
ATOM   8954  H HG13 . ILE B 1 253 ? 3.409   37.762  54.548 1.00 17.72 ?  219  ILE B HG13 1 
ATOM   8955  H HG21 . ILE B 1 253 ? 1.708   40.399  53.854 1.00 17.29 ?  219  ILE B HG21 1 
ATOM   8956  H HG22 . ILE B 1 253 ? 0.419   39.476  53.753 1.00 17.29 ?  219  ILE B HG22 1 
ATOM   8957  H HG23 . ILE B 1 253 ? 1.468   39.249  54.924 1.00 17.29 ?  219  ILE B HG23 1 
ATOM   8958  H HD11 . ILE B 1 253 ? 5.334   37.507  53.150 1.00 19.69 ?  219  ILE B HD11 1 
ATOM   8959  H HD12 . ILE B 1 253 ? 4.136   36.509  52.848 1.00 19.69 ?  219  ILE B HD12 1 
ATOM   8960  H HD13 . ILE B 1 253 ? 4.365   37.779  51.921 1.00 19.69 ?  219  ILE B HD13 1 
ATOM   8961  N N    . ILE B 1 254 ? 0.143   36.634  54.964 1.00 11.99 ?  220  ILE B N    1 
ATOM   8962  C CA   . ILE B 1 254 ? -0.037  35.825  56.171 1.00 12.85 ?  220  ILE B CA   1 
ATOM   8963  C C    . ILE B 1 254 ? -0.493  34.426  55.764 1.00 11.89 ?  220  ILE B C    1 
ATOM   8964  O O    . ILE B 1 254 ? -1.507  34.255  55.062 1.00 12.60 ?  220  ILE B O    1 
ATOM   8965  C CB   . ILE B 1 254 ? -1.010  36.485  57.149 1.00 12.89 ?  220  ILE B CB   1 
ATOM   8966  C CG1  . ILE B 1 254 ? -0.398  37.763  57.726 1.00 13.67 ?  220  ILE B CG1  1 
ATOM   8967  C CG2  . ILE B 1 254 ? -1.365  35.469  58.291 1.00 14.13 ?  220  ILE B CG2  1 
ATOM   8968  C CD1  . ILE B 1 254 ? -1.342  38.537  58.599 1.00 15.92 ?  220  ILE B CD1  1 
ATOM   8969  H H    . ILE B 1 254 ? -0.455  37.240  54.842 1.00 14.39 ?  220  ILE B H    1 
ATOM   8970  H HA   . ILE B 1 254 ? 0.815   35.751  56.630 1.00 15.42 ?  220  ILE B HA   1 
ATOM   8971  H HB   . ILE B 1 254 ? -1.823  36.729  56.679 1.00 15.47 ?  220  ILE B HB   1 
ATOM   8972  H HG12 . ILE B 1 254 ? 0.375   37.526  58.262 1.00 16.40 ?  220  ILE B HG12 1 
ATOM   8973  H HG13 . ILE B 1 254 ? -0.130  38.340  56.994 1.00 16.40 ?  220  ILE B HG13 1 
ATOM   8974  H HG21 . ILE B 1 254 ? -1.888  35.925  58.968 1.00 16.95 ?  220  ILE B HG21 1 
ATOM   8975  H HG22 . ILE B 1 254 ? -1.878  34.737  57.914 1.00 16.95 ?  220  ILE B HG22 1 
ATOM   8976  H HG23 . ILE B 1 254 ? -0.543  35.131  58.680 1.00 16.95 ?  220  ILE B HG23 1 
ATOM   8977  H HD11 . ILE B 1 254 ? -0.964  39.412  58.776 1.00 19.10 ?  220  ILE B HD11 1 
ATOM   8978  H HD12 . ILE B 1 254 ? -2.192  38.630  58.141 1.00 19.10 ?  220  ILE B HD12 1 
ATOM   8979  H HD13 . ILE B 1 254 ? -1.467  38.057  59.433 1.00 19.10 ?  220  ILE B HD13 1 
ATOM   8980  N N    . ARG B 1 255 ? 0.208   33.407  56.256 1.00 12.88 ?  221  ARG B N    1 
ATOM   8981  C CA   . ARG B 1 255 ? 0.024   32.030  55.834 1.00 11.85 ?  221  ARG B CA   1 
ATOM   8982  C C    . ARG B 1 255 ? 0.819   31.145  56.766 1.00 12.19 ?  221  ARG B C    1 
ATOM   8983  O O    . ARG B 1 255 ? 2.017   31.359  56.999 1.00 12.64 ?  221  ARG B O    1 
ATOM   8984  C CB   . ARG B 1 255 ? 0.559   31.868  54.422 1.00 12.26 ?  221  ARG B CB   1 
ATOM   8985  C CG   . ARG B 1 255 ? 0.218   30.504  53.783 1.00 13.78 ?  221  ARG B CG   1 
ATOM   8986  C CD   . ARG B 1 255 ? -1.175  30.448  53.193 1.00 11.74 ?  221  ARG B CD   1 
ATOM   8987  N NE   . ARG B 1 255 ? -1.326  31.455  52.135 1.00 12.90 ?  221  ARG B NE   1 
ATOM   8988  C CZ   . ARG B 1 255 ? -0.849  31.324  50.906 1.00 13.36 ?  221  ARG B CZ   1 
ATOM   8989  N NH1  . ARG B 1 255 ? -0.116  30.275  50.557 1.00 12.92 ?  221  ARG B NH1  1 
ATOM   8990  N NH2  . ARG B 1 255 ? -1.082  32.278  50.007 1.00 13.06 ?  221  ARG B NH2  1 
ATOM   8991  H H    . ARG B 1 255 ? 0.817   33.494  56.857 1.00 15.46 ?  221  ARG B H    1 
ATOM   8992  H HA   . ARG B 1 255 ? -0.913  31.781  55.848 1.00 14.22 ?  221  ARG B HA   1 
ATOM   8993  H HB2  . ARG B 1 255 ? 0.177   32.562  53.862 1.00 14.71 ?  221  ARG B HB2  1 
ATOM   8994  H HB3  . ARG B 1 255 ? 1.525   31.953  54.443 1.00 14.71 ?  221  ARG B HB3  1 
ATOM   8995  H HG2  . ARG B 1 255 ? 0.850   30.324  53.069 1.00 16.54 ?  221  ARG B HG2  1 
ATOM   8996  H HG3  . ARG B 1 255 ? 0.280   29.814  54.462 1.00 16.54 ?  221  ARG B HG3  1 
ATOM   8997  H HD2  . ARG B 1 255 ? -1.330  29.571  52.809 1.00 14.08 ?  221  ARG B HD2  1 
ATOM   8998  H HD3  . ARG B 1 255 ? -1.829  30.628  53.886 1.00 14.08 ?  221  ARG B HD3  1 
ATOM   8999  H HE   . ARG B 1 255 ? -1.753  32.177  52.325 1.00 15.48 ?  221  ARG B HE   1 
ATOM   9000  H HH11 . ARG B 1 255 ? 0.057   29.661  51.134 1.00 15.50 ?  221  ARG B HH11 1 
ATOM   9001  H HH12 . ARG B 1 255 ? 0.185   30.209  49.754 1.00 15.50 ?  221  ARG B HH12 1 
ATOM   9002  H HH21 . ARG B 1 255 ? -1.540  32.973  50.226 1.00 15.67 ?  221  ARG B HH21 1 
ATOM   9003  H HH22 . ARG B 1 255 ? -0.775  32.200  49.207 1.00 15.67 ?  221  ARG B HH22 1 
ATOM   9004  N N    . VAL B 1 256 ? 0.183   30.100  57.252 1.00 12.84 ?  222  VAL B N    1 
ATOM   9005  C CA   . VAL B 1 256 ? 0.904   29.115  58.049 1.00 13.28 ?  222  VAL B CA   1 
ATOM   9006  C C    . VAL B 1 256 ? 1.889   28.405  57.135 1.00 13.09 ?  222  VAL B C    1 
ATOM   9007  O O    . VAL B 1 256 ? 1.516   27.801  56.124 1.00 13.93 ?  222  VAL B O    1 
ATOM   9008  C CB   . VAL B 1 256 ? -0.068  28.134  58.717 1.00 14.48 ?  222  VAL B CB   1 
ATOM   9009  C CG1  . VAL B 1 256 ? 0.702   26.986  59.379 1.00 16.13 ?  222  VAL B CG1  1 
ATOM   9010  C CG2  . VAL B 1 256 ? -0.935  28.843  59.710 1.00 14.94 ?  222  VAL B CG2  1 
ATOM   9011  H H    . VAL B 1 256 ? -0.654  29.935  57.140 1.00 15.41 ?  222  VAL B H    1 
ATOM   9012  H HA   . VAL B 1 256 ? 1.402   29.558  58.753 1.00 15.94 ?  222  VAL B HA   1 
ATOM   9013  H HB   . VAL B 1 256 ? -0.647  27.754  58.039 1.00 17.37 ?  222  VAL B HB   1 
ATOM   9014  H HG11 . VAL B 1 256 ? 0.101   26.499  59.963 1.00 19.36 ?  222  VAL B HG11 1 
ATOM   9015  H HG12 . VAL B 1 256 ? 1.043   26.396  58.689 1.00 19.36 ?  222  VAL B HG12 1 
ATOM   9016  H HG13 . VAL B 1 256 ? 1.437   27.354  59.893 1.00 19.36 ?  222  VAL B HG13 1 
ATOM   9017  H HG21 . VAL B 1 256 ? -1.543  28.203  60.113 1.00 17.93 ?  222  VAL B HG21 1 
ATOM   9018  H HG22 . VAL B 1 256 ? -0.373  29.240  60.394 1.00 17.93 ?  222  VAL B HG22 1 
ATOM   9019  H HG23 . VAL B 1 256 ? -1.438  29.535  59.253 1.00 17.93 ?  222  VAL B HG23 1 
ATOM   9020  N N    . ARG B 1 257 ? 3.167   28.441  57.514 1.00 12.12 ?  223  ARG B N    1 
ATOM   9021  C CA   . ARG B 1 257 ? 4.259   27.900  56.749 1.00 12.69 ?  223  ARG B CA   1 
ATOM   9022  C C    . ARG B 1 257 ? 5.350   27.403  57.703 1.00 11.95 ?  223  ARG B C    1 
ATOM   9023  O O    . ARG B 1 257 ? 5.776   28.177  58.565 1.00 13.50 ?  223  ARG B O    1 
ATOM   9024  C CB   . ARG B 1 257 ? 4.926   28.926  55.812 1.00 14.66 ?  223  ARG B CB   1 
ATOM   9025  C CG   . ARG B 1 257 ? 4.067   29.470  54.662 1.00 12.24 ?  223  ARG B CG   1 
ATOM   9026  C CD   . ARG B 1 257 ? 3.663   28.415  53.663 1.00 14.79 ?  223  ARG B CD   1 
ATOM   9027  N NE   . ARG B 1 257 ? 4.730   27.518  53.233 1.00 13.39 ?  223  ARG B NE   1 
ATOM   9028  C CZ   . ARG B 1 257 ? 4.594   26.598  52.291 1.00 14.09 ?  223  ARG B CZ   1 
ATOM   9029  N NH1  . ARG B 1 257 ? 3.470   26.483  51.614 1.00 14.91 ?  223  ARG B NH1  1 
ATOM   9030  N NH2  . ARG B 1 257 ? 5.585   25.745  52.060 1.00 14.60 ?  223  ARG B NH2  1 
ATOM   9031  H H    . ARG B 1 257 ? 3.428   28.794  58.253 1.00 14.55 ?  223  ARG B H    1 
ATOM   9032  H HA   . ARG B 1 257 ? 3.891   27.165  56.234 1.00 15.23 ?  223  ARG B HA   1 
ATOM   9033  H HB2  . ARG B 1 257 ? 5.199   29.688  56.346 1.00 17.59 ?  223  ARG B HB2  1 
ATOM   9034  H HB3  . ARG B 1 257 ? 5.703   28.506  55.411 1.00 17.59 ?  223  ARG B HB3  1 
ATOM   9035  H HG2  . ARG B 1 257 ? 3.256   29.855  55.031 1.00 14.68 ?  223  ARG B HG2  1 
ATOM   9036  H HG3  . ARG B 1 257 ? 4.571   30.150  54.188 1.00 14.68 ?  223  ARG B HG3  1 
ATOM   9037  H HD2  . ARG B 1 257 ? 2.968   27.867  54.060 1.00 17.75 ?  223  ARG B HD2  1 
ATOM   9038  H HD3  . ARG B 1 257 ? 3.323   28.859  52.870 1.00 17.75 ?  223  ARG B HD3  1 
ATOM   9039  H HE   . ARG B 1 257 ? 5.496   27.590  53.617 1.00 16.07 ?  223  ARG B HE   1 
ATOM   9040  H HH11 . ARG B 1 257 ? 2.811   27.009  51.781 1.00 17.89 ?  223  ARG B HH11 1 
ATOM   9041  H HH12 . ARG B 1 257 ? 3.396   25.881  51.004 1.00 17.89 ?  223  ARG B HH12 1 
ATOM   9042  H HH21 . ARG B 1 257 ? 6.309   25.793  52.522 1.00 17.52 ?  223  ARG B HH21 1 
ATOM   9043  H HH22 . ARG B 1 257 ? 5.503   25.146  51.449 1.00 17.52 ?  223  ARG B HH22 1 
ATOM   9044  N N    . PRO B 1 258 ? 5.903   26.206  57.506 1.00 12.01 ?  224  PRO B N    1 
ATOM   9045  C CA   . PRO B 1 258 ? 7.042   25.820  58.367 1.00 13.23 ?  224  PRO B CA   1 
ATOM   9046  C C    . PRO B 1 258 ? 8.236   26.719  58.218 1.00 14.99 ?  224  PRO B C    1 
ATOM   9047  O O    . PRO B 1 258 ? 9.048   26.848  59.155 1.00 15.57 ?  224  PRO B O    1 
ATOM   9048  C CB   . PRO B 1 258 ? 7.360   24.383  57.960 1.00 14.45 ?  224  PRO B CB   1 
ATOM   9049  C CG   . PRO B 1 258 ? 6.307   23.959  57.023 1.00 18.30 ?  224  PRO B CG   1 
ATOM   9050  C CD   . PRO B 1 258 ? 5.482   25.142  56.600 1.00 11.69 ?  224  PRO B CD   1 
ATOM   9051  H HA   . PRO B 1 258 ? 6.752   25.817  59.293 1.00 15.88 ?  224  PRO B HA   1 
ATOM   9052  H HB2  . PRO B 1 258 ? 8.229   24.355  57.530 1.00 17.34 ?  224  PRO B HB2  1 
ATOM   9053  H HB3  . PRO B 1 258 ? 7.361   23.818  58.748 1.00 17.34 ?  224  PRO B HB3  1 
ATOM   9054  H HG2  . PRO B 1 258 ? 6.727   23.559  56.245 1.00 21.96 ?  224  PRO B HG2  1 
ATOM   9055  H HG3  . PRO B 1 258 ? 5.742   23.308  57.466 1.00 21.96 ?  224  PRO B HG3  1 
ATOM   9056  H HD2  . PRO B 1 258 ? 5.671   25.381  55.679 1.00 14.02 ?  224  PRO B HD2  1 
ATOM   9057  H HD3  . PRO B 1 258 ? 4.536   24.956  56.706 1.00 14.02 ?  224  PRO B HD3  1 
ATOM   9058  N N    . GLU B 1 259 ? 8.408   27.342  57.057 1.00 13.91 ?  225  GLU B N    1 
ATOM   9059  C CA   . GLU B 1 259 ? 9.534   28.217  56.784 1.00 13.90 ?  225  GLU B CA   1 
ATOM   9060  C C    . GLU B 1 259 ? 9.427   29.566  57.477 1.00 14.44 ?  225  GLU B C    1 
ATOM   9061  O O    . GLU B 1 259 ? 10.427  30.279  57.564 1.00 17.33 ?  225  GLU B O    1 
ATOM   9062  C CB   . GLU B 1 259 ? 9.614   28.460  55.250 1.00 15.12 ?  225  GLU B CB   1 
ATOM   9063  C CG   . GLU B 1 259 ? 9.695   27.193  54.381 1.00 14.93 ?  225  GLU B CG   1 
ATOM   9064  C CD   . GLU B 1 259 ? 8.365   26.597  53.982 1.00 14.89 ?  225  GLU B CD   1 
ATOM   9065  O OE1  . GLU B 1 259 ? 7.309   27.047  54.477 1.00 14.00 ?  225  GLU B OE1  1 
ATOM   9066  O OE2  . GLU B 1 259 ? 8.381   25.618  53.187 1.00 16.92 ?  225  GLU B OE2  1 
ATOM   9067  H H    . GLU B 1 259 ? 7.868   27.271  56.391 1.00 16.69 ?  225  GLU B H    1 
ATOM   9068  H HA   . GLU B 1 259 ? 10.342  27.784  57.101 1.00 16.68 ?  225  GLU B HA   1 
ATOM   9069  H HB2  . GLU B 1 259 ? 8.821   28.947  54.977 1.00 18.14 ?  225  GLU B HB2  1 
ATOM   9070  H HB3  . GLU B 1 259 ? 10.407  28.987  55.066 1.00 18.14 ?  225  GLU B HB3  1 
ATOM   9071  H HG2  . GLU B 1 259 ? 10.169  27.412  53.564 1.00 17.91 ?  225  GLU B HG2  1 
ATOM   9072  H HG3  . GLU B 1 259 ? 10.180  26.513  54.874 1.00 17.91 ?  225  GLU B HG3  1 
ATOM   9073  N N    . PHE B 1 260 ? 8.243   29.952  57.941 1.00 12.83 ?  226  PHE B N    1 
ATOM   9074  C CA   . PHE B 1 260 ? 7.996   31.257  58.529 1.00 13.59 ?  226  PHE B CA   1 
ATOM   9075  C C    . PHE B 1 260 ? 7.664   31.045  60.000 1.00 15.42 ?  226  PHE B C    1 
ATOM   9076  O O    . PHE B 1 260 ? 6.552   30.656  60.346 1.00 13.80 ?  226  PHE B O    1 
ATOM   9077  C CB   . PHE B 1 260 ? 6.745   31.918  57.919 1.00 15.12 ?  226  PHE B CB   1 
ATOM   9078  C CG   . PHE B 1 260 ? 6.745   32.196  56.410 1.00 16.92 ?  226  PHE B CG   1 
ATOM   9079  C CD1  . PHE B 1 260 ? 7.851   32.051  55.621 1.00 15.97 ?  226  PHE B CD1  1 
ATOM   9080  C CD2  . PHE B 1 260 ? 5.546   32.649  55.835 1.00 16.09 ?  226  PHE B CD2  1 
ATOM   9081  C CE1  . PHE B 1 260 ? 7.765   32.330  54.208 1.00 15.86 ?  226  PHE B CE1  1 
ATOM   9082  C CE2  . PHE B 1 260 ? 5.472   32.938  54.449 1.00 16.70 ?  226  PHE B CE2  1 
ATOM   9083  C CZ   . PHE B 1 260 ? 6.575   32.741  53.664 1.00 16.04 ?  226  PHE B CZ   1 
ATOM   9084  H H    . PHE B 1 260 ? 7.543   29.452  57.924 1.00 15.40 ?  226  PHE B H    1 
ATOM   9085  H HA   . PHE B 1 260 ? 8.793   31.793  58.393 1.00 16.31 ?  226  PHE B HA   1 
ATOM   9086  H HB2  . PHE B 1 260 ? 5.988   31.338  58.095 1.00 18.14 ?  226  PHE B HB2  1 
ATOM   9087  H HB3  . PHE B 1 260 ? 6.617   32.773  58.359 1.00 18.14 ?  226  PHE B HB3  1 
ATOM   9088  H HD1  . PHE B 1 260 ? 8.656   31.773  55.993 1.00 19.16 ?  226  PHE B HD1  1 
ATOM   9089  H HD2  . PHE B 1 260 ? 4.793   32.761  56.370 1.00 19.30 ?  226  PHE B HD2  1 
ATOM   9090  H HE1  . PHE B 1 260 ? 8.515   32.232  53.667 1.00 19.03 ?  226  PHE B HE1  1 
ATOM   9091  H HE2  . PHE B 1 260 ? 4.681   33.257  54.077 1.00 20.04 ?  226  PHE B HE2  1 
ATOM   9092  H HZ   . PHE B 1 260 ? 6.518   32.889  52.748 1.00 19.25 ?  226  PHE B HZ   1 
ATOM   9093  N N    . GLU B 1 261 ? 8.618   31.336  60.886 1.00 14.27 ?  227  GLU B N    1 
ATOM   9094  C CA   . GLU B 1 261 ? 8.346   31.162  62.309 1.00 15.96 ?  227  GLU B CA   1 
ATOM   9095  C C    . GLU B 1 261 ? 7.170   31.993  62.794 1.00 14.56 ?  227  GLU B C    1 
ATOM   9096  O O    . GLU B 1 261 ? 6.479   31.598  63.744 1.00 15.33 ?  227  GLU B O    1 
ATOM   9097  C CB   . GLU B 1 261 ? 9.598   31.498  63.117 1.00 19.44 ?  227  GLU B CB   1 
ATOM   9098  C CG   . GLU B 1 261 ? 10.668  30.416  63.044 1.00 20.55 ?  227  GLU B CG   1 
ATOM   9099  C CD   . GLU B 1 261 ? 11.501  30.481  61.795 1.00 20.88 ?  227  GLU B CD   1 
ATOM   9100  O OE1  . GLU B 1 261 ? 11.342  31.427  60.986 1.00 22.05 ?  227  GLU B OE1  1 
ATOM   9101  O OE2  . GLU B 1 261 ? 12.340  29.572  61.596 1.00 23.18 ?  227  GLU B OE2  1 
ATOM   9102  H H    . GLU B 1 261 ? 9.405   31.626  60.694 1.00 17.12 ?  227  GLU B H    1 
ATOM   9103  H HA   . GLU B 1 261 ? 8.116   30.232  62.459 1.00 19.16 ?  227  GLU B HA   1 
ATOM   9104  H HB2  . GLU B 1 261 ? 9.982   32.321  62.774 1.00 23.33 ?  227  GLU B HB2  1 
ATOM   9105  H HB3  . GLU B 1 261 ? 9.351   31.611  64.048 1.00 23.33 ?  227  GLU B HB3  1 
ATOM   9106  H HG2  . GLU B 1 261 ? 11.263  30.512  63.803 1.00 24.66 ?  227  GLU B HG2  1 
ATOM   9107  H HG3  . GLU B 1 261 ? 10.237  29.547  63.068 1.00 24.66 ?  227  GLU B HG3  1 
ATOM   9108  N N    . GLU B 1 262 ? 6.878   33.131  62.147 1.00 13.49 ?  228  GLU B N    1 
ATOM   9109  C CA   . GLU B 1 262 ? 5.745   33.966  62.532 1.00 14.25 ?  228  GLU B CA   1 
ATOM   9110  C C    . GLU B 1 262 ? 4.595   33.891  61.530 1.00 12.61 ?  228  GLU B C    1 
ATOM   9111  O O    . GLU B 1 262 ? 3.689   34.733  61.549 1.00 14.37 ?  228  GLU B O    1 
ATOM   9112  C CB   . GLU B 1 262 ? 6.156   35.417  62.771 1.00 16.20 ?  228  GLU B CB   1 
ATOM   9113  C CG   . GLU B 1 262 ? 7.197   35.606  63.851 1.00 15.56 ?  228  GLU B CG   1 
ATOM   9114  C CD   . GLU B 1 262 ? 7.667   37.050  63.947 1.00 25.62 ?  228  GLU B CD   1 
ATOM   9115  O OE1  . GLU B 1 262 ? 6.870   37.875  64.403 1.00 32.96 ?  228  GLU B OE1  1 
ATOM   9116  O OE2  . GLU B 1 262 ? 8.814   37.322  63.538 1.00 37.24 ?  228  GLU B OE2  1 
ATOM   9117  H H    . GLU B 1 262 ? 7.327   33.436  61.480 1.00 16.19 ?  228  GLU B H    1 
ATOM   9118  H HA   . GLU B 1 262 ? 5.420   33.636  63.385 1.00 17.10 ?  228  GLU B HA   1 
ATOM   9119  H HB2  . GLU B 1 262 ? 6.522   35.773  61.946 1.00 19.44 ?  228  GLU B HB2  1 
ATOM   9120  H HB3  . GLU B 1 262 ? 5.370   35.922  63.031 1.00 19.44 ?  228  GLU B HB3  1 
ATOM   9121  H HG2  . GLU B 1 262 ? 6.817   35.353  64.707 1.00 18.68 ?  228  GLU B HG2  1 
ATOM   9122  H HG3  . GLU B 1 262 ? 7.967   35.049  63.653 1.00 18.68 ?  228  GLU B HG3  1 
ATOM   9123  N N    . ASN B 1 263 ? 4.627   32.909  60.616 1.00 12.72 ?  229  ASN B N    1 
ATOM   9124  C CA   . ASN B 1 263 ? 3.528   32.641  59.698 1.00 13.24 ?  229  ASN B CA   1 
ATOM   9125  C C    . ASN B 1 263 ? 3.179   33.863  58.873 1.00 14.75 ?  229  ASN B C    1 
ATOM   9126  O O    . ASN B 1 263 ? 2.009   34.103  58.551 1.00 13.51 ?  229  ASN B O    1 
ATOM   9127  C CB   . ASN B 1 263 ? 2.347   32.037  60.450 1.00 13.74 ?  229  ASN B CB   1 
ATOM   9128  C CG   . ASN B 1 263 ? 2.668   30.633  60.945 1.00 12.98 ?  229  ASN B CG   1 
ATOM   9129  O OD1  . ASN B 1 263 ? 3.348   29.881  60.243 1.00 14.38 ?  229  ASN B OD1  1 
ATOM   9130  N ND2  . ASN B 1 263 ? 2.246   30.316  62.175 1.00 15.08 ?  229  ASN B ND2  1 
ATOM   9131  H H    . ASN B 1 263 ? 5.293   32.376  60.512 1.00 15.26 ?  229  ASN B H    1 
ATOM   9132  H HA   . ASN B 1 263 ? 3.798   31.979  59.043 1.00 15.89 ?  229  ASN B HA   1 
ATOM   9133  H HB2  . ASN B 1 263 ? 2.137   32.592  61.217 1.00 16.49 ?  229  ASN B HB2  1 
ATOM   9134  H HB3  . ASN B 1 263 ? 1.581   31.986  59.858 1.00 16.49 ?  229  ASN B HB3  1 
ATOM   9135  H HD21 . ASN B 1 263 ? 2.405   29.534  62.495 1.00 18.10 ?  229  ASN B HD21 1 
ATOM   9136  H HD22 . ASN B 1 263 ? 1.816   30.894  62.644 1.00 18.10 ?  229  ASN B HD22 1 
ATOM   9137  N N    . GLY B 1 264 ? 4.208   34.604  58.487 1.00 14.03 ?  230  GLY B N    1 
ATOM   9138  C CA   . GLY B 1 264 ? 4.105   35.698  57.556 1.00 12.95 ?  230  GLY B CA   1 
ATOM   9139  C C    . GLY B 1 264 ? 4.155   37.062  58.191 1.00 14.71 ?  230  GLY B C    1 
ATOM   9140  O O    . GLY B 1 264 ? 4.419   38.039  57.480 1.00 14.23 ?  230  GLY B O    1 
ATOM   9141  H H    . GLY B 1 264 ? 5.011   34.480  58.768 1.00 16.84 ?  230  GLY B H    1 
ATOM   9142  H HA2  . GLY B 1 264 ? 4.835   35.638  56.921 1.00 15.55 ?  230  GLY B HA2  1 
ATOM   9143  H HA3  . GLY B 1 264 ? 3.264   35.623  57.078 1.00 15.55 ?  230  GLY B HA3  1 
ATOM   9144  N N    . LEU B 1 265 ? 3.918   37.186  59.501 1.00 14.51 ?  231  LEU B N    1 
ATOM   9145  C CA   . LEU B 1 265 ? 4.039   38.479  60.170 1.00 15.15 ?  231  LEU B CA   1 
ATOM   9146  C C    . LEU B 1 265 ? 5.414   39.090  59.976 1.00 16.48 ?  231  LEU B C    1 
ATOM   9147  O O    . LEU B 1 265 ? 5.559   40.322  59.970 1.00 16.38 ?  231  LEU B O    1 
ATOM   9148  C CB   . LEU B 1 265 ? 3.823   38.361  61.670 1.00 16.35 ?  231  LEU B CB   1 
ATOM   9149  C CG   . LEU B 1 265 ? 2.450   37.913  62.046 1.00 16.45 ?  231  LEU B CG   1 
ATOM   9150  C CD1  . LEU B 1 265 ? 2.312   37.905  63.613 1.00 21.59 ?  231  LEU B CD1  1 
ATOM   9151  C CD2  . LEU B 1 265 ? 1.370   38.785  61.380 1.00 19.85 ?  231  LEU B CD2  1 
ATOM   9152  H H    . LEU B 1 265 ? 3.687   36.540  60.020 1.00 17.41 ?  231  LEU B H    1 
ATOM   9153  H HA   . LEU B 1 265 ? 3.351   39.047  59.787 1.00 18.18 ?  231  LEU B HA   1 
ATOM   9154  H HB2  . LEU B 1 265 ? 4.454   37.715  62.024 1.00 19.62 ?  231  LEU B HB2  1 
ATOM   9155  H HB3  . LEU B 1 265 ? 3.974   39.229  62.075 1.00 19.62 ?  231  LEU B HB3  1 
ATOM   9156  H HG   . LEU B 1 265 ? 2.305   37.010  61.723 1.00 19.74 ?  231  LEU B HG   1 
ATOM   9157  H HD11 . LEU B 1 265 ? 1.425   37.593  63.850 1.00 25.90 ?  231  LEU B HD11 1 
ATOM   9158  H HD12 . LEU B 1 265 ? 2.982   37.312  63.986 1.00 25.90 ?  231  LEU B HD12 1 
ATOM   9159  H HD13 . LEU B 1 265 ? 2.446   38.806  63.946 1.00 25.90 ?  231  LEU B HD13 1 
ATOM   9160  H HD21 . LEU B 1 265 ? 0.518   38.617  61.813 1.00 23.82 ?  231  LEU B HD21 1 
ATOM   9161  H HD22 . LEU B 1 265 ? 1.612   39.719  61.478 1.00 23.82 ?  231  LEU B HD22 1 
ATOM   9162  H HD23 . LEU B 1 265 ? 1.314   38.555  60.439 1.00 23.82 ?  231  LEU B HD23 1 
ATOM   9163  N N    . GLU B 1 266 ? 6.430   38.270  59.818 1.00 16.03 ?  232  GLU B N    1 
ATOM   9164  C CA   . GLU B 1 266 ? 7.762   38.839  59.716 1.00 17.77 ?  232  GLU B CA   1 
ATOM   9165  C C    . GLU B 1 266 ? 7.962   39.639  58.439 1.00 18.85 ?  232  GLU B C    1 
ATOM   9166  O O    . GLU B 1 266 ? 8.915   40.413  58.358 1.00 18.44 ?  232  GLU B O    1 
ATOM   9167  C CB   . GLU B 1 266 ? 8.845   37.769  59.947 1.00 20.69 ?  232  GLU B CB   1 
ATOM   9168  C CG   . GLU B 1 266 ? 8.812   36.558  59.022 1.00 18.11 ?  232  GLU B CG   1 
ATOM   9169  C CD   . GLU B 1 266 ? 7.952   35.408  59.536 1.00 15.74 ?  232  GLU B CD   1 
ATOM   9170  O OE1  . GLU B 1 266 ? 6.723   35.535  59.426 1.00 14.51 ?  232  GLU B OE1  1 
ATOM   9171  O OE2  . GLU B 1 266 ? 8.450   34.334  60.004 1.00 15.98 ?  232  GLU B OE2  1 
ATOM   9172  H H    . GLU B 1 266 ? 6.381   37.412  59.768 1.00 19.23 ?  232  GLU B H    1 
ATOM   9173  H HA   . GLU B 1 266 ? 7.896   39.469  60.440 1.00 21.32 ?  232  GLU B HA   1 
ATOM   9174  H HB2  . GLU B 1 266 ? 9.712   38.189  59.834 1.00 24.83 ?  232  GLU B HB2  1 
ATOM   9175  H HB3  . GLU B 1 266 ? 8.752   37.437  60.853 1.00 24.83 ?  232  GLU B HB3  1 
ATOM   9176  H HG2  . GLU B 1 266 ? 8.454   36.832  58.163 1.00 21.73 ?  232  GLU B HG2  1 
ATOM   9177  H HG3  . GLU B 1 266 ? 9.716   36.224  58.914 1.00 21.73 ?  232  GLU B HG3  1 
ATOM   9178  N N    . TYR B 1 267 ? 7.041   39.560  57.488 1.00 16.39 ?  233  TYR B N    1 
ATOM   9179  C CA   . TYR B 1 267 ? 7.121   40.310  56.249 1.00 16.40 ?  233  TYR B CA   1 
ATOM   9180  C C    . TYR B 1 267 ? 6.091   41.432  56.161 1.00 16.08 ?  233  TYR B C    1 
ATOM   9181  O O    . TYR B 1 267 ? 6.101   42.206  55.196 1.00 16.82 ?  233  TYR B O    1 
ATOM   9182  C CB   . TYR B 1 267 ? 6.935   39.371  55.052 1.00 18.48 ?  233  TYR B CB   1 
ATOM   9183  C CG   . TYR B 1 267 ? 7.829   38.165  55.123 1.00 17.03 ?  233  TYR B CG   1 
ATOM   9184  C CD1  . TYR B 1 267 ? 9.230   38.281  54.988 1.00 19.01 ?  233  TYR B CD1  1 
ATOM   9185  C CD2  . TYR B 1 267 ? 7.311   36.904  55.367 1.00 18.70 ?  233  TYR B CD2  1 
ATOM   9186  C CE1  . TYR B 1 267 ? 10.036  37.153  55.078 1.00 18.97 ?  233  TYR B CE1  1 
ATOM   9187  C CE2  . TYR B 1 267 ? 8.113   35.785  55.449 1.00 19.19 ?  233  TYR B CE2  1 
ATOM   9188  C CZ   . TYR B 1 267 ? 9.464   35.901  55.296 1.00 24.35 ?  233  TYR B CZ   1 
ATOM   9189  O OH   . TYR B 1 267 ? 10.271  34.773  55.392 1.00 24.40 ?  233  TYR B OH   1 
ATOM   9190  H H    . TYR B 1 267 ? 6.341   39.064  57.541 1.00 19.67 ?  233  TYR B H    1 
ATOM   9191  H HA   . TYR B 1 267 ? 8.005   40.707  56.194 1.00 19.67 ?  233  TYR B HA   1 
ATOM   9192  H HB2  . TYR B 1 267 ? 6.015   39.064  55.031 1.00 22.17 ?  233  TYR B HB2  1 
ATOM   9193  H HB3  . TYR B 1 267 ? 7.142   39.853  54.236 1.00 22.17 ?  233  TYR B HB3  1 
ATOM   9194  H HD1  . TYR B 1 267 ? 9.614   39.115  54.839 1.00 22.81 ?  233  TYR B HD1  1 
ATOM   9195  H HD2  . TYR B 1 267 ? 6.392   36.809  55.478 1.00 22.44 ?  233  TYR B HD2  1 
ATOM   9196  H HE1  . TYR B 1 267 ? 10.959  37.234  54.993 1.00 22.76 ?  233  TYR B HE1  1 
ATOM   9197  H HE2  . TYR B 1 267 ? 7.733   34.951  55.610 1.00 23.03 ?  233  TYR B HE2  1 
ATOM   9198  H HH   . TYR B 1 267 ? 11.059  34.965  55.173 1.00 29.28 ?  233  TYR B HH   1 
ATOM   9199  N N    . LEU B 1 268 ? 5.242   41.559  57.151 1.00 14.47 ?  234  LEU B N    1 
ATOM   9200  C CA   . LEU B 1 268 ? 4.080   42.444  57.045 1.00 16.54 ?  234  LEU B CA   1 
ATOM   9201  C C    . LEU B 1 268 ? 4.459   43.913  57.134 1.00 18.70 ?  234  LEU B C    1 
ATOM   9202  O O    . LEU B 1 268 ? 3.634   44.779  56.786 1.00 18.08 ?  234  LEU B O    1 
ATOM   9203  C CB   . LEU B 1 268 ? 3.069   42.030  58.126 1.00 15.26 ?  234  LEU B CB   1 
ATOM   9204  C CG   . LEU B 1 268 ? 1.668   42.634  57.998 1.00 16.27 ?  234  LEU B CG   1 
ATOM   9205  C CD1  . LEU B 1 268 ? 1.049   42.367  56.638 1.00 19.95 ?  234  LEU B CD1  1 
ATOM   9206  C CD2  . LEU B 1 268 ? 0.827   42.090  59.089 1.00 17.72 ?  234  LEU B CD2  1 
ATOM   9207  H H    . LEU B 1 268 ? 5.304   41.147  57.903 1.00 17.36 ?  234  LEU B H    1 
ATOM   9208  H HA   . LEU B 1 268 ? 3.647   42.345  56.183 1.00 19.85 ?  234  LEU B HA   1 
ATOM   9209  H HB2  . LEU B 1 268 ? 2.970   41.066  58.094 1.00 18.32 ?  234  LEU B HB2  1 
ATOM   9210  H HB3  . LEU B 1 268 ? 3.420   42.300  58.989 1.00 18.32 ?  234  LEU B HB3  1 
ATOM   9211  H HG   . LEU B 1 268 ? 1.722   43.600  58.074 1.00 19.52 ?  234  LEU B HG   1 
ATOM   9212  H HD11 . LEU B 1 268 ? 0.117   42.634  56.658 1.00 23.95 ?  234  LEU B HD11 1 
ATOM   9213  H HD12 . LEU B 1 268 ? 1.526   42.879  55.967 1.00 23.95 ?  234  LEU B HD12 1 
ATOM   9214  H HD13 . LEU B 1 268 ? 1.117   41.419  56.441 1.00 23.95 ?  234  LEU B HD13 1 
ATOM   9215  H HD21 . LEU B 1 268 ? -0.086  42.395  58.965 1.00 21.27 ?  234  LEU B HD21 1 
ATOM   9216  H HD22 . LEU B 1 268 ? 0.859   41.121  59.059 1.00 21.27 ?  234  LEU B HD22 1 
ATOM   9217  H HD23 . LEU B 1 268 ? 1.169   42.407  59.939 1.00 21.27 ?  234  LEU B HD23 1 
ATOM   9218  N N    . GLY B 1 269 ? 5.669   44.238  57.599 1.00 16.87 ?  235  GLY B N    1 
ATOM   9219  C CA   . GLY B 1 269 ? 6.071   45.633  57.669 1.00 17.27 ?  235  GLY B CA   1 
ATOM   9220  C C    . GLY B 1 269 ? 6.148   46.342  56.339 1.00 15.66 ?  235  GLY B C    1 
ATOM   9221  O O    . GLY B 1 269 ? 6.107   47.585  56.310 1.00 16.75 ?  235  GLY B O    1 
ATOM   9222  H H    . GLY B 1 269 ? 6.260   43.677  57.872 1.00 20.25 ?  235  GLY B H    1 
ATOM   9223  H HA2  . GLY B 1 269 ? 5.434   46.112  58.222 1.00 20.72 ?  235  GLY B HA2  1 
ATOM   9224  H HA3  . GLY B 1 269 ? 6.947   45.683  58.082 1.00 20.72 ?  235  GLY B HA3  1 
ATOM   9225  N N    . TYR B 1 270 ? 6.206   45.613  55.233 1.00 14.16 ?  236  TYR B N    1 
ATOM   9226  C CA   . TYR B 1 270 ? 6.208   46.264  53.928 1.00 13.92 ?  236  TYR B CA   1 
ATOM   9227  C C    . TYR B 1 270 ? 4.826   46.759  53.503 1.00 14.24 ?  236  TYR B C    1 
ATOM   9228  O O    . TYR B 1 270 ? 4.730   47.547  52.552 1.00 14.79 ?  236  TYR B O    1 
ATOM   9229  C CB   . TYR B 1 270 ? 6.646   45.292  52.834 1.00 14.91 ?  236  TYR B CB   1 
ATOM   9230  C CG   . TYR B 1 270 ? 8.100   44.902  52.901 1.00 17.60 ?  236  TYR B CG   1 
ATOM   9231  C CD1  . TYR B 1 270 ? 9.059   45.795  52.533 1.00 16.21 ?  236  TYR B CD1  1 
ATOM   9232  C CD2  . TYR B 1 270 ? 8.491   43.628  53.284 1.00 23.31 ?  236  TYR B CD2  1 
ATOM   9233  C CE1  . TYR B 1 270 ? 10.418  45.447  52.565 1.00 19.08 ?  236  TYR B CE1  1 
ATOM   9234  C CE2  . TYR B 1 270 ? 9.841   43.270  53.339 1.00 28.30 ?  236  TYR B CE2  1 
ATOM   9235  C CZ   . TYR B 1 270 ? 10.789  44.189  52.958 1.00 24.09 ?  236  TYR B CZ   1 
ATOM   9236  O OH   . TYR B 1 270 ? 12.142  43.858  52.975 1.00 26.87 ?  236  TYR B OH   1 
ATOM   9237  H H    . TYR B 1 270 ? 6.244   44.755  55.211 1.00 16.99 ?  236  TYR B H    1 
ATOM   9238  H HA   . TYR B 1 270 ? 6.833   47.003  53.990 1.00 16.70 ?  236  TYR B HA   1 
ATOM   9239  H HB2  . TYR B 1 270 ? 6.119   44.481  52.911 1.00 17.89 ?  236  TYR B HB2  1 
ATOM   9240  H HB3  . TYR B 1 270 ? 6.492   45.707  51.971 1.00 17.89 ?  236  TYR B HB3  1 
ATOM   9241  H HD1  . TYR B 1 270 ? 8.811   46.647  52.256 1.00 19.45 ?  236  TYR B HD1  1 
ATOM   9242  H HD2  . TYR B 1 270 ? 7.843   43.000  53.509 1.00 27.97 ?  236  TYR B HD2  1 
ATOM   9243  H HE1  . TYR B 1 270 ? 11.064  46.068  52.320 1.00 22.89 ?  236  TYR B HE1  1 
ATOM   9244  H HE2  . TYR B 1 270 ? 10.094  42.423  53.629 1.00 33.96 ?  236  TYR B HE2  1 
ATOM   9245  H HH   . TYR B 1 270 ? 12.241  43.065  53.232 1.00 32.24 ?  236  TYR B HH   1 
ATOM   9246  N N    . PHE B 1 271 ? 3.754   46.341  54.178 1.00 12.08 ?  237  PHE B N    1 
ATOM   9247  C CA   . PHE B 1 271 ? 2.416   46.452  53.621 1.00 10.91 ?  237  PHE B CA   1 
ATOM   9248  C C    . PHE B 1 271 ? 1.464   47.077  54.626 1.00 13.00 ?  237  PHE B C    1 
ATOM   9249  O O    . PHE B 1 271 ? 1.707   47.078  55.826 1.00 14.24 ?  237  PHE B O    1 
ATOM   9250  C CB   . PHE B 1 271 ? 1.901   45.058  53.256 1.00 12.98 ?  237  PHE B CB   1 
ATOM   9251  C CG   . PHE B 1 271 ? 2.865   44.273  52.403 1.00 12.83 ?  237  PHE B CG   1 
ATOM   9252  C CD1  . PHE B 1 271 ? 3.217   44.700  51.149 1.00 13.07 ?  237  PHE B CD1  1 
ATOM   9253  C CD2  . PHE B 1 271 ? 3.430   43.113  52.877 1.00 13.94 ?  237  PHE B CD2  1 
ATOM   9254  C CE1  . PHE B 1 271 ? 4.088   43.971  50.363 1.00 15.69 ?  237  PHE B CE1  1 
ATOM   9255  C CE2  . PHE B 1 271 ? 4.293   42.362  52.073 1.00 13.88 ?  237  PHE B CE2  1 
ATOM   9256  C CZ   . PHE B 1 271 ? 4.634   42.794  50.866 1.00 13.27 ?  237  PHE B CZ   1 
ATOM   9257  H H    . PHE B 1 271 ? 3.782   45.988  54.962 1.00 14.49 ?  237  PHE B H    1 
ATOM   9258  H HA   . PHE B 1 271 ? 2.436   47.029  52.842 1.00 13.09 ?  237  PHE B HA   1 
ATOM   9259  H HB2  . PHE B 1 271 ? 1.748   44.556  54.072 1.00 15.57 ?  237  PHE B HB2  1 
ATOM   9260  H HB3  . PHE B 1 271 ? 1.072   45.149  52.762 1.00 15.57 ?  237  PHE B HB3  1 
ATOM   9261  H HD1  . PHE B 1 271 ? 2.863   45.495  50.821 1.00 15.68 ?  237  PHE B HD1  1 
ATOM   9262  H HD2  . PHE B 1 271 ? 3.236   42.824  53.740 1.00 16.73 ?  237  PHE B HD2  1 
ATOM   9263  H HE1  . PHE B 1 271 ? 4.307   44.263  49.507 1.00 18.82 ?  237  PHE B HE1  1 
ATOM   9264  H HE2  . PHE B 1 271 ? 4.631   41.554  52.387 1.00 16.65 ?  237  PHE B HE2  1 
ATOM   9265  H HZ   . PHE B 1 271 ? 5.240   42.309  50.355 1.00 15.92 ?  237  PHE B HZ   1 
ATOM   9266  N N    . ASN B 1 272 ? 0.329   47.558  54.120 1.00 12.17 ?  238  ASN B N    1 
ATOM   9267  C CA   . ASN B 1 272 ? -0.725  48.053  55.001 1.00 12.75 ?  238  ASN B CA   1 
ATOM   9268  C C    . ASN B 1 272 ? -1.628  46.950  55.539 1.00 12.68 ?  238  ASN B C    1 
ATOM   9269  O O    . ASN B 1 272 ? -2.397  47.178  56.455 1.00 12.57 ?  238  ASN B O    1 
ATOM   9270  C CB   . ASN B 1 272 ? -1.595  49.105  54.281 1.00 12.26 ?  238  ASN B CB   1 
ATOM   9271  C CG   . ASN B 1 272 ? -0.814  50.303  53.814 1.00 14.27 ?  238  ASN B CG   1 
ATOM   9272  O OD1  . ASN B 1 272 ? -0.679  50.549  52.635 1.00 13.34 ?  238  ASN B OD1  1 
ATOM   9273  N ND2  . ASN B 1 272 ? -0.294  51.067  54.770 1.00 15.29 ?  238  ASN B ND2  1 
ATOM   9274  H H    . ASN B 1 272 ? 0.148   47.607  53.281 1.00 14.60 ?  238  ASN B H    1 
ATOM   9275  H HA   . ASN B 1 272 ? -0.296  48.487  55.755 1.00 15.30 ?  238  ASN B HA   1 
ATOM   9276  H HB2  . ASN B 1 272 ? -2.005  48.695  53.503 1.00 14.71 ?  238  ASN B HB2  1 
ATOM   9277  H HB3  . ASN B 1 272 ? -2.281  49.417  54.892 1.00 14.71 ?  238  ASN B HB3  1 
ATOM   9278  H HD21 . ASN B 1 272 ? 0.163   51.766  54.562 1.00 18.35 ?  238  ASN B HD21 1 
ATOM   9279  H HD22 . ASN B 1 272 ? -0.415  50.863  55.597 1.00 18.35 ?  238  ASN B HD22 1 
ATOM   9280  N N    . GLY B 1 273 ? -1.531  45.742  55.000 1.00 13.74 ?  239  GLY B N    1 
ATOM   9281  C CA   . GLY B 1 273 ? -2.312  44.626  55.507 1.00 12.84 ?  239  GLY B CA   1 
ATOM   9282  C C    . GLY B 1 273 ? -2.085  43.399  54.666 1.00 10.79 ?  239  GLY B C    1 
ATOM   9283  O O    . GLY B 1 273 ? -1.292  43.391  53.732 1.00 11.96 ?  239  GLY B O    1 
ATOM   9284  H H    . GLY B 1 273 ? -1.019  45.543  54.339 1.00 16.49 ?  239  GLY B H    1 
ATOM   9285  H HA2  . GLY B 1 273 ? -2.053  44.431  56.421 1.00 15.40 ?  239  GLY B HA2  1 
ATOM   9286  H HA3  . GLY B 1 273 ? -3.256  44.849  55.486 1.00 15.40 ?  239  GLY B HA3  1 
ATOM   9287  N N    . SER B 1 274 ? -2.783  42.345  55.076 1.00 12.70 ?  240  SER B N    1 
ATOM   9288  C CA   . SER B 1 274 ? -2.714  41.068  54.383 1.00 10.80 ?  240  SER B CA   1 
ATOM   9289  C C    . SER B 1 274 ? -4.091  40.589  53.974 1.00 11.00 ?  240  SER B C    1 
ATOM   9290  O O    . SER B 1 274 ? -5.056  40.655  54.747 1.00 11.70 ?  240  SER B O    1 
ATOM   9291  C CB   . SER B 1 274 ? -2.088  39.973  55.291 1.00 12.90 ?  240  SER B CB   1 
ATOM   9292  O OG   . SER B 1 274 ? -1.812  38.774  54.563 1.00 12.78 ?  240  SER B OG   1 
ATOM   9293  H H    . SER B 1 274 ? -3.306  42.347  55.758 1.00 15.24 ?  240  SER B H    1 
ATOM   9294  H HA   . SER B 1 274 ? -2.180  41.193  53.583 1.00 12.96 ?  240  SER B HA   1 
ATOM   9295  H HB2  . SER B 1 274 ? -1.258  40.312  55.661 1.00 15.49 ?  240  SER B HB2  1 
ATOM   9296  H HB3  . SER B 1 274 ? -2.711  39.768  56.006 1.00 15.49 ?  240  SER B HB3  1 
ATOM   9297  H HG   . SER B 1 274 ? -2.488  38.543  54.122 1.00 15.34 ?  240  SER B HG   1 
ATOM   9298  N N    . TYR B 1 275 ? -4.105  40.000  52.786 1.00 11.08 ?  241  TYR B N    1 
ATOM   9299  C CA   . TYR B 1 275 ? -5.168  39.095  52.374 1.00 11.66 ?  241  TYR B CA   1 
ATOM   9300  C C    . TYR B 1 275 ? -4.811  37.704  52.856 1.00 11.96 ?  241  TYR B C    1 
ATOM   9301  O O    . TYR B 1 275 ? -3.625  37.373  53.013 1.00 11.87 ?  241  TYR B O    1 
ATOM   9302  C CB   . TYR B 1 275 ? -5.244  39.169  50.841 1.00 12.32 ?  241  TYR B CB   1 
ATOM   9303  C CG   . TYR B 1 275 ? -5.825  38.008  50.052 1.00 10.82 ?  241  TYR B CG   1 
ATOM   9304  C CD1  . TYR B 1 275 ? -5.065  36.860  49.837 1.00 11.77 ?  241  TYR B CD1  1 
ATOM   9305  C CD2  . TYR B 1 275 ? -7.083  38.074  49.475 1.00 11.97 ?  241  TYR B CD2  1 
ATOM   9306  C CE1  . TYR B 1 275 ? -5.525  35.817  49.088 1.00 11.47 ?  241  TYR B CE1  1 
ATOM   9307  C CE2  . TYR B 1 275 ? -7.551  37.008  48.665 1.00 12.02 ?  241  TYR B CE2  1 
ATOM   9308  C CZ   . TYR B 1 275 ? -6.785  35.886  48.493 1.00 11.95 ?  241  TYR B CZ   1 
ATOM   9309  O OH   . TYR B 1 275 ? -7.282  34.873  47.741 1.00 12.13 ?  241  TYR B OH   1 
ATOM   9310  H H    . TYR B 1 275 ? -3.497  40.111  52.188 1.00 13.30 ?  241  TYR B H    1 
ATOM   9311  H HA   . TYR B 1 275 ? -6.039  39.314  52.738 1.00 13.99 ?  241  TYR B HA   1 
ATOM   9312  H HB2  . TYR B 1 275 ? -5.783  39.943  50.618 1.00 14.78 ?  241  TYR B HB2  1 
ATOM   9313  H HB3  . TYR B 1 275 ? -4.338  39.290  50.514 1.00 14.78 ?  241  TYR B HB3  1 
ATOM   9314  H HD1  . TYR B 1 275 ? -4.218  36.803  50.217 1.00 14.12 ?  241  TYR B HD1  1 
ATOM   9315  H HD2  . TYR B 1 275 ? -7.621  38.819  49.619 1.00 14.36 ?  241  TYR B HD2  1 
ATOM   9316  H HE1  . TYR B 1 275 ? -4.997  35.059  48.974 1.00 13.77 ?  241  TYR B HE1  1 
ATOM   9317  H HE2  . TYR B 1 275 ? -8.381  37.071  48.249 1.00 14.42 ?  241  TYR B HE2  1 
ATOM   9318  H HH   . TYR B 1 275 ? -6.667  34.337  47.538 1.00 14.56 ?  241  TYR B HH   1 
ATOM   9319  N N    . LEU B 1 276 ? -5.844  36.930  53.155 1.00 11.74 ?  242  LEU B N    1 
ATOM   9320  C CA   . LEU B 1 276 ? -5.685  35.562  53.633 1.00 11.20 ?  242  LEU B CA   1 
ATOM   9321  C C    . LEU B 1 276 ? -6.363  34.593  52.687 1.00 11.62 ?  242  LEU B C    1 
ATOM   9322  O O    . LEU B 1 276 ? -7.550  34.760  52.393 1.00 12.78 ?  242  LEU B O    1 
ATOM   9323  C CB   . LEU B 1 276 ? -6.298  35.339  55.023 1.00 11.69 ?  242  LEU B CB   1 
ATOM   9324  C CG   . LEU B 1 276 ? -5.899  36.354  56.081 1.00 12.95 ?  242  LEU B CG   1 
ATOM   9325  C CD1  . LEU B 1 276 ? -6.756  36.198  57.316 1.00 13.76 ?  242  LEU B CD1  1 
ATOM   9326  C CD2  . LEU B 1 276 ? -4.429  36.240  56.446 1.00 15.43 ?  242  LEU B CD2  1 
ATOM   9327  H H    . LEU B 1 276 ? -6.664  37.179  53.087 1.00 14.09 ?  242  LEU B H    1 
ATOM   9328  H HA   . LEU B 1 276 ? -4.731  35.391  53.668 1.00 13.44 ?  242  LEU B HA   1 
ATOM   9329  H HB2  . LEU B 1 276 ? -7.263  35.372  54.939 1.00 14.03 ?  242  LEU B HB2  1 
ATOM   9330  H HB3  . LEU B 1 276 ? -6.022  34.465  55.340 1.00 14.03 ?  242  LEU B HB3  1 
ATOM   9331  H HG   . LEU B 1 276 ? -6.040  37.240  55.714 1.00 15.53 ?  242  LEU B HG   1 
ATOM   9332  H HD11 . LEU B 1 276 ? -6.462  36.834  57.987 1.00 16.51 ?  242  LEU B HD11 1 
ATOM   9333  H HD12 . LEU B 1 276 ? -7.681  36.369  57.082 1.00 16.51 ?  242  LEU B HD12 1 
ATOM   9334  H HD13 . LEU B 1 276 ? -6.662  35.294  57.654 1.00 16.51 ?  242  LEU B HD13 1 
ATOM   9335  H HD21 . LEU B 1 276 ? -4.221  36.900  57.126 1.00 18.52 ?  242  LEU B HD21 1 
ATOM   9336  H HD22 . LEU B 1 276 ? -4.256  35.349  56.787 1.00 18.52 ?  242  LEU B HD22 1 
ATOM   9337  H HD23 . LEU B 1 276 ? -3.894  36.401  55.653 1.00 18.52 ?  242  LEU B HD23 1 
ATOM   9338  N N    . GLU B 1 277 ? -5.633  33.551  52.273 1.00 12.00 ?  243  GLU B N    1 
ATOM   9339  C CA   . GLU B 1 277 ? -6.209  32.395  51.600 1.00 12.26 ?  243  GLU B CA   1 
ATOM   9340  C C    . GLU B 1 277 ? -5.502  31.156  52.128 1.00 11.93 ?  243  GLU B C    1 
ATOM   9341  O O    . GLU B 1 277 ? -4.484  31.226  52.828 1.00 12.48 ?  243  GLU B O    1 
ATOM   9342  C CB   . GLU B 1 277 ? -6.091  32.502  50.078 1.00 11.28 ?  243  GLU B CB   1 
ATOM   9343  C CG   . GLU B 1 277 ? -4.653  32.445  49.550 1.00 11.48 ?  243  GLU B CG   1 
ATOM   9344  C CD   . GLU B 1 277 ? -4.523  32.571  48.044 1.00 10.65 ?  243  GLU B CD   1 
ATOM   9345  O OE1  . GLU B 1 277 ? -5.561  32.872  47.382 1.00 12.58 ?  243  GLU B OE1  1 
ATOM   9346  O OE2  . GLU B 1 277 ? -3.425  32.341  47.513 1.00 11.68 ?  243  GLU B OE2  1 
ATOM   9347  H H    . GLU B 1 277 ? -4.781  33.495  52.376 1.00 14.40 ?  243  GLU B H    1 
ATOM   9348  H HA   . GLU B 1 277 ? -7.155  32.326  51.804 1.00 14.72 ?  243  GLU B HA   1 
ATOM   9349  H HB2  . GLU B 1 277 ? -6.580  31.767  49.677 1.00 13.53 ?  243  GLU B HB2  1 
ATOM   9350  H HB3  . GLU B 1 277 ? -6.473  33.348  49.796 1.00 13.53 ?  243  GLU B HB3  1 
ATOM   9351  H HG2  . GLU B 1 277 ? -4.149  33.172  49.948 1.00 13.77 ?  243  GLU B HG2  1 
ATOM   9352  H HG3  . GLU B 1 277 ? -4.264  31.594  49.806 1.00 13.77 ?  243  GLU B HG3  1 
ATOM   9353  N N    . GLY B 1 278 ? -6.006  30.006  51.730 1.00 12.52 ?  244  GLY B N    1 
ATOM   9354  C CA   . GLY B 1 278 ? -5.560  28.755  52.306 1.00 13.43 ?  244  GLY B CA   1 
ATOM   9355  C C    . GLY B 1 278 ? -5.744  28.689  53.800 1.00 15.24 ?  244  GLY B C    1 
ATOM   9356  O O    . GLY B 1 278 ? -5.041  27.916  54.480 1.00 15.44 ?  244  GLY B O    1 
ATOM   9357  H H    . GLY B 1 278 ? -6.611  29.920  51.125 1.00 15.03 ?  244  GLY B H    1 
ATOM   9358  H HA2  . GLY B 1 278 ? -6.060  28.026  51.907 1.00 16.11 ?  244  GLY B HA2  1 
ATOM   9359  H HA3  . GLY B 1 278 ? -4.617  28.635  52.112 1.00 16.11 ?  244  GLY B HA3  1 
ATOM   9360  N N    . PHE B 1 279 ? -6.642  29.485  54.358 1.00 12.76 ?  245  PHE B N    1 
ATOM   9361  C CA   . PHE B 1 279 ? -6.652  29.726  55.793 1.00 13.89 ?  245  PHE B CA   1 
ATOM   9362  C C    . PHE B 1 279 ? -7.158  28.527  56.574 1.00 14.76 ?  245  PHE B C    1 
ATOM   9363  O O    . PHE B 1 279 ? -6.714  28.286  57.698 1.00 14.31 ?  245  PHE B O    1 
ATOM   9364  C CB   . PHE B 1 279 ? -7.491  30.984  56.079 1.00 12.46 ?  245  PHE B CB   1 
ATOM   9365  C CG   . PHE B 1 279 ? -7.304  31.564  57.459 1.00 12.56 ?  245  PHE B CG   1 
ATOM   9366  C CD1  . PHE B 1 279 ? -6.110  32.191  57.782 1.00 11.68 ?  245  PHE B CD1  1 
ATOM   9367  C CD2  . PHE B 1 279 ? -8.284  31.475  58.450 1.00 12.45 ?  245  PHE B CD2  1 
ATOM   9368  C CE1  . PHE B 1 279 ? -5.899  32.739  59.014 1.00 14.45 ?  245  PHE B CE1  1 
ATOM   9369  C CE2  . PHE B 1 279 ? -8.091  32.023  59.701 1.00 15.14 ?  245  PHE B CE2  1 
ATOM   9370  C CZ   . PHE B 1 279 ? -6.871  32.670  59.986 1.00 13.65 ?  245  PHE B CZ   1 
ATOM   9371  H H    . PHE B 1 279 ? -7.260  29.901  53.928 1.00 15.31 ?  245  PHE B H    1 
ATOM   9372  H HA   . PHE B 1 279 ? -5.747  29.889  56.104 1.00 16.67 ?  245  PHE B HA   1 
ATOM   9373  H HB2  . PHE B 1 279 ? -7.247  31.670  55.438 1.00 14.96 ?  245  PHE B HB2  1 
ATOM   9374  H HB3  . PHE B 1 279 ? -8.429  30.757  55.982 1.00 14.96 ?  245  PHE B HB3  1 
ATOM   9375  H HD1  . PHE B 1 279 ? -5.436  32.239  57.143 1.00 14.01 ?  245  PHE B HD1  1 
ATOM   9376  H HD2  . PHE B 1 279 ? -9.082  31.037  58.262 1.00 14.94 ?  245  PHE B HD2  1 
ATOM   9377  H HE1  . PHE B 1 279 ? -5.092  33.163  59.199 1.00 17.33 ?  245  PHE B HE1  1 
ATOM   9378  H HE2  . PHE B 1 279 ? -8.757  31.967  60.347 1.00 18.17 ?  245  PHE B HE2  1 
ATOM   9379  H HZ   . PHE B 1 279 ? -6.725  33.046  60.824 1.00 16.38 ?  245  PHE B HZ   1 
ATOM   9380  N N    . ASP B 1 280 ? -8.051  27.744  55.980 1.00 14.64 ?  246  ASP B N    1 
ATOM   9381  C CA   . ASP B 1 280 ? -8.615  26.543  56.588 1.00 15.47 ?  246  ASP B CA   1 
ATOM   9382  C C    . ASP B 1 280 ? -8.188  25.293  55.839 1.00 16.54 ?  246  ASP B C    1 
ATOM   9383  O O    . ASP B 1 280 ? -8.839  24.241  55.973 1.00 17.62 ?  246  ASP B O    1 
ATOM   9384  C CB   . ASP B 1 280 ? -10.138 26.652  56.670 1.00 15.33 ?  246  ASP B CB   1 
ATOM   9385  C CG   . ASP B 1 280 ? -10.805 26.800  55.313 1.00 17.83 ?  246  ASP B CG   1 
ATOM   9386  O OD1  . ASP B 1 280 ? -10.152 27.011  54.264 1.00 15.76 ?  246  ASP B OD1  1 
ATOM   9387  O OD2  . ASP B 1 280 ? -12.062 26.642  55.294 1.00 20.40 ?  246  ASP B OD2  1 
ATOM   9388  H H    . ASP B 1 280 ? -8.360  27.893  55.192 1.00 17.57 ?  246  ASP B H    1 
ATOM   9389  H HA   . ASP B 1 280 ? -8.292  26.463  57.499 1.00 18.56 ?  246  ASP B HA   1 
ATOM   9390  H HB2  . ASP B 1 280 ? -10.488 25.850  57.088 1.00 18.39 ?  246  ASP B HB2  1 
ATOM   9391  H HB3  . ASP B 1 280 ? -10.369 27.430  57.201 1.00 18.39 ?  246  ASP B HB3  1 
ATOM   9392  N N    . SER B 1 281 ? -7.130  25.372  55.044 1.00 14.42 ?  247  SER B N    1 
ATOM   9393  C CA   . SER B 1 281 ? -6.670  24.262  54.227 1.00 16.42 ?  247  SER B CA   1 
ATOM   9394  C C    . SER B 1 281 ? -5.332  23.824  54.809 1.00 16.93 ?  247  SER B C    1 
ATOM   9395  O O    . SER B 1 281 ? -4.288  24.295  54.408 1.00 17.10 ?  247  SER B O    1 
ATOM   9396  C CB   . SER B 1 281 ? -6.490  24.700  52.792 1.00 25.22 ?  247  SER B CB   1 
ATOM   9397  O OG   . SER B 1 281 ? -6.344  23.557  51.963 1.00 36.50 ?  247  SER B OG   1 
ATOM   9398  H H    . SER B 1 281 ? -6.650  26.080  54.959 1.00 17.30 ?  247  SER B H    1 
ATOM   9399  H HA   . SER B 1 281 ? -7.310  23.534  54.266 1.00 19.71 ?  247  SER B HA   1 
ATOM   9400  H HB2  . SER B 1 281 ? -7.269  25.204  52.510 1.00 30.26 ?  247  SER B HB2  1 
ATOM   9401  H HB3  . SER B 1 281 ? -5.694  25.251  52.722 1.00 30.26 ?  247  SER B HB3  1 
ATOM   9402  H HG   . SER B 1 281 ? -6.244  23.792  51.164 1.00 43.80 ?  247  SER B HG   1 
ATOM   9403  N N    . GLU B 1 282 ? -5.372  22.822  55.687 1.00 15.85 ?  248  GLU B N    1 
ATOM   9404  C CA   . GLU B 1 282 ? -4.163  22.419  56.389 1.00 15.59 ?  248  GLU B CA   1 
ATOM   9405  C C    . GLU B 1 282 ? -3.169  21.705  55.473 1.00 17.14 ?  248  GLU B C    1 
ATOM   9406  O O    . GLU B 1 282 ? -3.488  21.172  54.413 1.00 18.54 ?  248  GLU B O    1 
ATOM   9407  C CB   . GLU B 1 282 ? -4.508  21.571  57.617 1.00 17.81 ?  248  GLU B CB   1 
ATOM   9408  C CG   . GLU B 1 282 ? -4.957  20.135  57.325 1.00 19.95 ?  248  GLU B CG   1 
ATOM   9409  C CD   . GLU B 1 282 ? -6.432  19.995  57.009 1.00 23.94 ?  248  GLU B CD   1 
ATOM   9410  O OE1  . GLU B 1 282 ? -7.162  21.009  56.856 1.00 19.81 ?  248  GLU B OE1  1 
ATOM   9411  O OE2  . GLU B 1 282 ? -6.879  18.829  56.891 1.00 25.85 ?  248  GLU B OE2  1 
ATOM   9412  H H    . GLU B 1 282 ? -6.076  22.369  55.888 1.00 19.02 ?  248  GLU B H    1 
ATOM   9413  H HA   . GLU B 1 282 ? -3.707  23.215  56.704 1.00 18.71 ?  248  GLU B HA   1 
ATOM   9414  H HB2  . GLU B 1 282 ? -3.721  21.518  58.182 1.00 21.37 ?  248  GLU B HB2  1 
ATOM   9415  H HB3  . GLU B 1 282 ? -5.230  22.008  58.096 1.00 21.37 ?  248  GLU B HB3  1 
ATOM   9416  H HG2  . GLU B 1 282 ? -4.460  19.804  56.561 1.00 23.94 ?  248  GLU B HG2  1 
ATOM   9417  H HG3  . GLU B 1 282 ? -4.771  19.588  58.104 1.00 23.94 ?  248  GLU B HG3  1 
ATOM   9418  N N    . ALA B 1 283 ? -1.910  21.724  55.909 1.00 16.31 ?  249  ALA B N    1 
ATOM   9419  C CA   . ALA B 1 283 ? -0.809  21.084  55.208 1.00 15.01 ?  249  ALA B CA   1 
ATOM   9420  C C    . ALA B 1 283 ? 0.258   20.722  56.237 1.00 14.77 ?  249  ALA B C    1 
ATOM   9421  O O    . ALA B 1 283 ? 0.072   20.927  57.443 1.00 15.96 ?  249  ALA B O    1 
ATOM   9422  C CB   . ALA B 1 283 ? -0.252  21.970  54.083 1.00 18.55 ?  249  ALA B CB   1 
ATOM   9423  H H    . ALA B 1 283 ? -1.664  22.116  56.633 1.00 19.57 ?  249  ALA B H    1 
ATOM   9424  H HA   . ALA B 1 283 ? -1.130  20.267  54.795 1.00 18.01 ?  249  ALA B HA   1 
ATOM   9425  H HB1  . ALA B 1 283 ? 0.464   21.495  53.632 1.00 22.26 ?  249  ALA B HB1  1 
ATOM   9426  H HB2  . ALA B 1 283 ? -0.964  22.168  53.455 1.00 22.26 ?  249  ALA B HB2  1 
ATOM   9427  H HB3  . ALA B 1 283 ? 0.089   22.793  54.467 1.00 22.26 ?  249  ALA B HB3  1 
ATOM   9428  N N    . PHE B 1 284 ? 1.366   20.193  55.755 1.00 16.34 ?  250  PHE B N    1 
ATOM   9429  C CA   . PHE B 1 284 ? 2.557   19.945  56.574 1.00 16.67 ?  250  PHE B CA   1 
ATOM   9430  C C    . PHE B 1 284 ? 2.322   18.898  57.658 1.00 18.06 ?  250  PHE B C    1 
ATOM   9431  O O    . PHE B 1 284 ? 3.048   18.865  58.651 1.00 18.41 ?  250  PHE B O    1 
ATOM   9432  C CB   . PHE B 1 284 ? 3.105   21.239  57.207 1.00 16.26 ?  250  PHE B CB   1 
ATOM   9433  C CG   . PHE B 1 284 ? 2.933   22.439  56.330 1.00 16.24 ?  250  PHE B CG   1 
ATOM   9434  C CD1  . PHE B 1 284 ? 3.580   22.507  55.109 1.00 15.31 ?  250  PHE B CD1  1 
ATOM   9435  C CD2  . PHE B 1 284 ? 2.094   23.469  56.704 1.00 15.02 ?  250  PHE B CD2  1 
ATOM   9436  C CE1  . PHE B 1 284 ? 3.408   23.611  54.260 1.00 16.06 ?  250  PHE B CE1  1 
ATOM   9437  C CE2  . PHE B 1 284 ? 1.910   24.558  55.863 1.00 15.92 ?  250  PHE B CE2  1 
ATOM   9438  C CZ   . PHE B 1 284 ? 2.559   24.617  54.656 1.00 15.55 ?  250  PHE B CZ   1 
ATOM   9439  H H    . PHE B 1 284 ? 1.462   19.959  54.933 1.00 19.61 ?  250  PHE B H    1 
ATOM   9440  H HA   . PHE B 1 284 ? 3.243   19.599  55.981 1.00 20.01 ?  250  PHE B HA   1 
ATOM   9441  H HB2  . PHE B 1 284 ? 2.634   21.406  58.038 1.00 19.51 ?  250  PHE B HB2  1 
ATOM   9442  H HB3  . PHE B 1 284 ? 4.053   21.128  57.380 1.00 19.51 ?  250  PHE B HB3  1 
ATOM   9443  H HD1  . PHE B 1 284 ? 4.137   21.809  54.846 1.00 18.37 ?  250  PHE B HD1  1 
ATOM   9444  H HD2  . PHE B 1 284 ? 1.652   23.433  57.521 1.00 18.03 ?  250  PHE B HD2  1 
ATOM   9445  H HE1  . PHE B 1 284 ? 3.859   23.662  53.449 1.00 19.28 ?  250  PHE B HE1  1 
ATOM   9446  H HE2  . PHE B 1 284 ? 1.344   25.251  56.119 1.00 19.11 ?  250  PHE B HE2  1 
ATOM   9447  H HZ   . PHE B 1 284 ? 2.423   25.347  54.098 1.00 18.67 ?  250  PHE B HZ   1 
ATOM   9448  N N    . GLY B 1 285 ? 1.308   18.057  57.503 1.00 16.39 ?  251  GLY B N    1 
ATOM   9449  C CA   . GLY B 1 285 ? 0.981   17.070  58.535 1.00 16.92 ?  251  GLY B CA   1 
ATOM   9450  C C    . GLY B 1 285 ? 0.249   17.631  59.731 1.00 19.06 ?  251  GLY B C    1 
ATOM   9451  O O    . GLY B 1 285 ? -0.010  16.914  60.702 1.00 19.94 ?  251  GLY B O    1 
ATOM   9452  H H    . GLY B 1 285 ? 0.794   18.034  56.814 1.00 19.66 ?  251  GLY B H    1 
ATOM   9453  H HA2  . GLY B 1 285 ? 0.423   16.382  58.142 1.00 20.31 ?  251  GLY B HA2  1 
ATOM   9454  H HA3  . GLY B 1 285 ? 1.804   16.667  58.853 1.00 20.31 ?  251  GLY B HA3  1 
ATOM   9455  N N    . MET B 1 286 ? -0.150  18.904  59.687 1.00 15.72 ?  252  MET B N    1 
ATOM   9456  C CA   . MET B 1 286 ? -0.829  19.533  60.787 1.00 16.29 ?  252  MET B CA   1 
ATOM   9457  C C    . MET B 1 286 ? -2.301  19.149  60.766 1.00 16.30 ?  252  MET B C    1 
ATOM   9458  O O    . MET B 1 286 ? -2.884  18.962  59.701 1.00 18.21 ?  252  MET B O    1 
ATOM   9459  C CB   . MET B 1 286 ? -0.690  21.041  60.546 1.00 16.11 ?  252  MET B CB   1 
ATOM   9460  C CG   . MET B 1 286 ? 0.640   21.600  60.941 1.00 14.16 ?  252  MET B CG   1 
ATOM   9461  S SD   . MET B 1 286 ? 0.764   23.365  60.626 1.00 17.12 ?  252  MET B SD   1 
ATOM   9462  C CE   . MET B 1 286 ? 0.285   23.951  62.234 1.00 17.55 ?  252  MET B CE   1 
ATOM   9463  H H    . MET B 1 286 ? -0.031  19.424  59.012 1.00 18.86 ?  252  MET B H    1 
ATOM   9464  H HA   . MET B 1 286 ? -0.463  19.280  61.649 1.00 19.55 ?  252  MET B HA   1 
ATOM   9465  H HB2  . MET B 1 286 ? -0.816  21.218  59.600 1.00 19.34 ?  252  MET B HB2  1 
ATOM   9466  H HB3  . MET B 1 286 ? -1.369  21.503  61.062 1.00 19.34 ?  252  MET B HB3  1 
ATOM   9467  H HG2  . MET B 1 286 ? 0.776   21.453  61.890 1.00 16.99 ?  252  MET B HG2  1 
ATOM   9468  H HG3  . MET B 1 286 ? 1.335   21.153  60.432 1.00 16.99 ?  252  MET B HG3  1 
ATOM   9469  H HE1  . MET B 1 286 ? 0.276   24.921  62.227 1.00 21.06 ?  252  MET B HE1  1 
ATOM   9470  H HE2  . MET B 1 286 ? -0.600  23.614  62.442 1.00 21.06 ?  252  MET B HE2  1 
ATOM   9471  H HE3  . MET B 1 286 ? 0.924   23.632  62.890 1.00 21.06 ?  252  MET B HE3  1 
ATOM   9472  N N    . SER B 1 287 ? -2.910  19.079  61.954 1.00 17.34 ?  253  SER B N    1 
ATOM   9473  C CA   . SER B 1 287 ? -4.355  18.958  61.991 1.00 18.30 ?  253  SER B CA   1 
ATOM   9474  C C    . SER B 1 287 ? -5.015  20.243  61.497 1.00 18.25 ?  253  SER B C    1 
ATOM   9475  O O    . SER B 1 287 ? -4.465  21.340  61.607 1.00 17.09 ?  253  SER B O    1 
ATOM   9476  C CB   . SER B 1 287 ? -4.855  18.681  63.410 1.00 16.90 ?  253  SER B CB   1 
ATOM   9477  O OG   . SER B 1 287 ? -4.683  19.757  64.293 1.00 19.27 ?  253  SER B OG   1 
ATOM   9478  H H    . SER B 1 287 ? -2.517  19.099  62.719 1.00 20.81 ?  253  SER B H    1 
ATOM   9479  H HA   . SER B 1 287 ? -4.612  18.216  61.421 1.00 21.95 ?  253  SER B HA   1 
ATOM   9480  H HB2  . SER B 1 287 ? -5.802  18.474  63.363 1.00 20.28 ?  253  SER B HB2  1 
ATOM   9481  H HB3  . SER B 1 287 ? -4.367  17.919  63.760 1.00 20.28 ?  253  SER B HB3  1 
ATOM   9482  H HG   . SER B 1 287 ? -3.878  19.811  64.527 1.00 23.12 ?  253  SER B HG   1 
ATOM   9483  N N    . ASN B 1 288 ? -6.222  20.099  60.975 1.00 16.28 ?  254  ASN B N    1 
ATOM   9484  C CA   . ASN B 1 288 ? -6.989  21.276  60.582 1.00 15.26 ?  254  ASN B CA   1 
ATOM   9485  C C    . ASN B 1 288 ? -7.126  22.245  61.737 1.00 16.43 ?  254  ASN B C    1 
ATOM   9486  O O    . ASN B 1 288 ? -6.955  23.460  61.574 1.00 15.54 ?  254  ASN B O    1 
ATOM   9487  C CB   . ASN B 1 288 ? -8.359  20.843  60.057 1.00 17.54 ?  254  ASN B CB   1 
ATOM   9488  C CG   . ASN B 1 288 ? -9.218  22.020  59.635 1.00 20.30 ?  254  ASN B CG   1 
ATOM   9489  O OD1  . ASN B 1 288 ? -10.079 22.463  60.390 1.00 21.12 ?  254  ASN B OD1  1 
ATOM   9490  N ND2  . ASN B 1 288 ? -8.971  22.515  58.447 1.00 20.03 ?  254  ASN B ND2  1 
ATOM   9491  H H    . ASN B 1 288 ? -6.617  19.347  60.839 1.00 19.53 ?  254  ASN B H    1 
ATOM   9492  H HA   . ASN B 1 288 ? -6.530  21.738  59.863 1.00 18.32 ?  254  ASN B HA   1 
ATOM   9493  H HB2  . ASN B 1 288 ? -8.235  20.269  59.285 1.00 21.04 ?  254  ASN B HB2  1 
ATOM   9494  H HB3  . ASN B 1 288 ? -8.829  20.363  60.756 1.00 21.04 ?  254  ASN B HB3  1 
ATOM   9495  H HD21 . ASN B 1 288 ? -9.428  23.183  58.156 1.00 24.03 ?  254  ASN B HD21 1 
ATOM   9496  H HD22 . ASN B 1 288 ? -8.353  22.172  57.959 1.00 24.03 ?  254  ASN B HD22 1 
ATOM   9497  N N    . ALA B 1 289 ? -7.444  21.754  62.941 1.00 16.23 ?  255  ALA B N    1 
ATOM   9498  C CA   . ALA B 1 289 ? -7.665  22.639  64.058 1.00 15.26 ?  255  ALA B CA   1 
ATOM   9499  C C    . ALA B 1 289 ? -6.382  23.369  64.442 1.00 15.99 ?  255  ALA B C    1 
ATOM   9500  O O    . ALA B 1 289 ? -6.420  24.556  64.749 1.00 16.25 ?  255  ALA B O    1 
ATOM   9501  C CB   . ALA B 1 289 ? -8.216  21.860  65.251 1.00 18.50 ?  255  ALA B CB   1 
ATOM   9502  H H    . ALA B 1 289 ? -7.534  20.919  63.124 1.00 19.47 ?  255  ALA B H    1 
ATOM   9503  H HA   . ALA B 1 289 ? -8.327  23.301  63.804 1.00 18.31 ?  255  ALA B HA   1 
ATOM   9504  H HB1  . ALA B 1 289 ? -8.335  22.468  65.998 1.00 22.20 ?  255  ALA B HB1  1 
ATOM   9505  H HB2  . ALA B 1 289 ? -9.068  21.466  65.006 1.00 22.20 ?  255  ALA B HB2  1 
ATOM   9506  H HB3  . ALA B 1 289 ? -7.586  21.162  65.491 1.00 22.20 ?  255  ALA B HB3  1 
ATOM   9507  N N    . GLU B 1 290 ? -5.240  22.655  64.527 1.00 16.68 ?  256  GLU B N    1 
ATOM   9508  C CA   . GLU B 1 290 ? -4.020  23.363  64.956 1.00 16.35 ?  256  GLU B CA   1 
ATOM   9509  C C    . GLU B 1 290 ? -3.513  24.319  63.884 1.00 15.36 ?  256  GLU B C    1 
ATOM   9510  O O    . GLU B 1 290 ? -2.951  25.363  64.230 1.00 15.71 ?  256  GLU B O    1 
ATOM   9511  C CB   . GLU B 1 290 ? -2.919  22.403  65.430 1.00 17.65 ?  256  GLU B CB   1 
ATOM   9512  C CG   . GLU B 1 290 ? -3.286  21.675  66.729 1.00 19.86 ?  256  GLU B CG   1 
ATOM   9513  C CD   . GLU B 1 290 ? -2.461  20.433  66.953 1.00 21.05 ?  256  GLU B CD   1 
ATOM   9514  O OE1  . GLU B 1 290 ? -1.420  20.529  67.624 1.00 20.45 ?  256  GLU B OE1  1 
ATOM   9515  O OE2  . GLU B 1 290 ? -2.752  19.355  66.373 1.00 21.23 ?  256  GLU B OE2  1 
ATOM   9516  H H    . GLU B 1 290 ? -5.152  21.817  64.354 1.00 20.02 ?  256  GLU B H    1 
ATOM   9517  H HA   . GLU B 1 290 ? -4.249  23.890  65.738 1.00 19.63 ?  256  GLU B HA   1 
ATOM   9518  H HB2  . GLU B 1 290 ? -2.766  21.735  64.743 1.00 21.18 ?  256  GLU B HB2  1 
ATOM   9519  H HB3  . GLU B 1 290 ? -2.106  22.909  65.588 1.00 21.18 ?  256  GLU B HB3  1 
ATOM   9520  H HG2  . GLU B 1 290 ? -3.139  22.273  67.479 1.00 23.84 ?  256  GLU B HG2  1 
ATOM   9521  H HG3  . GLU B 1 290 ? -4.219  21.413  66.692 1.00 23.84 ?  256  GLU B HG3  1 
ATOM   9522  N N    . TYR B 1 291 ? -3.716  23.976  62.618 1.00 13.87 ?  257  TYR B N    1 
ATOM   9523  C CA   . TYR B 1 291 ? -3.397  24.885  61.503 1.00 14.79 ?  257  TYR B CA   1 
ATOM   9524  C C    . TYR B 1 291 ? -4.226  26.160  61.604 1.00 14.75 ?  257  TYR B C    1 
ATOM   9525  O O    . TYR B 1 291 ? -3.693  27.273  61.459 1.00 14.05 ?  257  TYR B O    1 
ATOM   9526  C CB   . TYR B 1 291 ? -3.655  24.174  60.188 1.00 15.22 ?  257  TYR B CB   1 
ATOM   9527  C CG   . TYR B 1 291 ? -3.361  24.920  58.918 1.00 13.74 ?  257  TYR B CG   1 
ATOM   9528  C CD1  . TYR B 1 291 ? -4.357  25.718  58.321 1.00 14.17 ?  257  TYR B CD1  1 
ATOM   9529  C CD2  . TYR B 1 291 ? -2.154  24.796  58.260 1.00 15.81 ?  257  TYR B CD2  1 
ATOM   9530  C CE1  . TYR B 1 291 ? -4.124  26.356  57.142 1.00 16.08 ?  257  TYR B CE1  1 
ATOM   9531  C CE2  . TYR B 1 291 ? -1.909  25.470  57.074 1.00 14.71 ?  257  TYR B CE2  1 
ATOM   9532  C CZ   . TYR B 1 291 ? -2.920  26.252  56.508 1.00 15.45 ?  257  TYR B CZ   1 
ATOM   9533  O OH   . TYR B 1 291 ? -2.630  26.875  55.303 1.00 16.98 ?  257  TYR B OH   1 
ATOM   9534  H H    . TYR B 1 291 ? -4.038  23.220  62.366 1.00 16.65 ?  257  TYR B H    1 
ATOM   9535  H HA   . TYR B 1 291 ? -2.459  25.132  61.532 1.00 17.75 ?  257  TYR B HA   1 
ATOM   9536  H HB2  . TYR B 1 291 ? -3.109  23.372  60.173 1.00 18.27 ?  257  TYR B HB2  1 
ATOM   9537  H HB3  . TYR B 1 291 ? -4.595  23.936  60.160 1.00 18.27 ?  257  TYR B HB3  1 
ATOM   9538  H HD1  . TYR B 1 291 ? -5.183  25.809  58.737 1.00 17.01 ?  257  TYR B HD1  1 
ATOM   9539  H HD2  . TYR B 1 291 ? -1.493  24.249  58.619 1.00 18.97 ?  257  TYR B HD2  1 
ATOM   9540  H HE1  . TYR B 1 291 ? -4.798  26.872  56.762 1.00 19.29 ?  257  TYR B HE1  1 
ATOM   9541  H HE2  . TYR B 1 291 ? -1.079  25.403  56.659 1.00 17.66 ?  257  TYR B HE2  1 
ATOM   9542  H HH   . TYR B 1 291 ? -3.337  27.006  54.870 1.00 20.38 ?  257  TYR B HH   1 
ATOM   9543  N N    . LEU B 1 292 ? -5.522  26.033  61.899 1.00 14.28 ?  258  LEU B N    1 
ATOM   9544  C CA   . LEU B 1 292 ? -6.337  27.230  62.102 1.00 13.79 ?  258  LEU B CA   1 
ATOM   9545  C C    . LEU B 1 292 ? -5.930  28.010  63.355 1.00 13.71 ?  258  LEU B C    1 
ATOM   9546  O O    . LEU B 1 292 ? -5.925  29.240  63.367 1.00 13.99 ?  258  LEU B O    1 
ATOM   9547  C CB   . LEU B 1 292 ? -7.835  26.863  62.154 1.00 15.07 ?  258  LEU B CB   1 
ATOM   9548  C CG   . LEU B 1 292 ? -8.443  26.857  60.758 1.00 14.10 ?  258  LEU B CG   1 
ATOM   9549  C CD1  . LEU B 1 292 ? -9.721  26.035  60.717 1.00 18.29 ?  258  LEU B CD1  1 
ATOM   9550  C CD2  . LEU B 1 292 ? -8.743  28.273  60.288 1.00 16.80 ?  258  LEU B CD2  1 
ATOM   9551  H H    . LEU B 1 292 ? -5.942  25.287  61.984 1.00 17.13 ?  258  LEU B H    1 
ATOM   9552  H HA   . LEU B 1 292 ? -6.196  27.814  61.340 1.00 16.55 ?  258  LEU B HA   1 
ATOM   9553  H HB2  . LEU B 1 292 ? -7.936  25.979  62.538 1.00 18.08 ?  258  LEU B HB2  1 
ATOM   9554  H HB3  . LEU B 1 292 ? -8.308  27.516  62.693 1.00 18.08 ?  258  LEU B HB3  1 
ATOM   9555  H HG   . LEU B 1 292 ? -7.797  26.456  60.156 1.00 16.92 ?  258  LEU B HG   1 
ATOM   9556  H HD11 . LEU B 1 292 ? -10.084 26.060  59.818 1.00 21.94 ?  258  LEU B HD11 1 
ATOM   9557  H HD12 . LEU B 1 292 ? -9.516  25.121  60.967 1.00 21.94 ?  258  LEU B HD12 1 
ATOM   9558  H HD13 . LEU B 1 292 ? -10.360 26.414  61.342 1.00 21.94 ?  258  LEU B HD13 1 
ATOM   9559  H HD21 . LEU B 1 292 ? -9.108  28.237  59.390 1.00 20.16 ?  258  LEU B HD21 1 
ATOM   9560  H HD22 . LEU B 1 292 ? -9.388  28.676  60.891 1.00 20.16 ?  258  LEU B HD22 1 
ATOM   9561  H HD23 . LEU B 1 292 ? -7.921  28.788  60.291 1.00 20.16 ?  258  LEU B HD23 1 
ATOM   9562  N N    . VAL B 1 293 ? -5.550  27.323  64.442 1.00 15.04 ?  259  VAL B N    1 
ATOM   9563  C CA   . VAL B 1 293 ? -5.120  28.035  65.624 1.00 15.59 ?  259  VAL B CA   1 
ATOM   9564  C C    . VAL B 1 293 ? -3.948  28.960  65.278 1.00 13.41 ?  259  VAL B C    1 
ATOM   9565  O O    . VAL B 1 293 ? -3.892  30.103  65.716 1.00 13.76 ?  259  VAL B O    1 
ATOM   9566  C CB   . VAL B 1 293 ? -4.750  27.027  66.733 1.00 17.27 ?  259  VAL B CB   1 
ATOM   9567  C CG1  . VAL B 1 293 ? -3.912  27.660  67.846 1.00 18.10 ?  259  VAL B CG1  1 
ATOM   9568  C CG2  . VAL B 1 293 ? -6.010  26.374  67.306 1.00 19.13 ?  259  VAL B CG2  1 
ATOM   9569  H H    . VAL B 1 293 ? -5.537  26.466  64.508 1.00 18.04 ?  259  VAL B H    1 
ATOM   9570  H HA   . VAL B 1 293 ? -5.848  28.587  65.951 1.00 18.71 ?  259  VAL B HA   1 
ATOM   9571  H HB   . VAL B 1 293 ? -4.198  26.340  66.328 1.00 20.73 ?  259  VAL B HB   1 
ATOM   9572  H HG11 . VAL B 1 293 ? -3.849  27.037  68.587 1.00 21.71 ?  259  VAL B HG11 1 
ATOM   9573  H HG12 . VAL B 1 293 ? -3.027  27.857  67.503 1.00 21.71 ?  259  VAL B HG12 1 
ATOM   9574  H HG13 . VAL B 1 293 ? -4.343  28.479  68.139 1.00 21.71 ?  259  VAL B HG13 1 
ATOM   9575  H HG21 . VAL B 1 293 ? -5.759  25.566  67.779 1.00 22.96 ?  259  VAL B HG21 1 
ATOM   9576  H HG22 . VAL B 1 293 ? -6.438  26.995  67.916 1.00 22.96 ?  259  VAL B HG22 1 
ATOM   9577  H HG23 . VAL B 1 293 ? -6.613  26.157  66.577 1.00 22.96 ?  259  VAL B HG23 1 
ATOM   9578  N N    . GLU B 1 294 ? -2.984  28.447  64.510 1.00 13.84 ?  260  GLU B N    1 
ATOM   9579  C CA   . GLU B 1 294 ? -1.814  29.256  64.147 1.00 14.95 ?  260  GLU B CA   1 
ATOM   9580  C C    . GLU B 1 294 ? -2.195  30.432  63.241 1.00 12.79 ?  260  GLU B C    1 
ATOM   9581  O O    . GLU B 1 294 ? -1.710  31.561  63.433 1.00 13.98 ?  260  GLU B O    1 
ATOM   9582  C CB   . GLU B 1 294 ? -0.720  28.375  63.551 1.00 16.66 ?  260  GLU B CB   1 
ATOM   9583  C CG   . GLU B 1 294 ? -0.113  27.434  64.618 1.00 15.16 ?  260  GLU B CG   1 
ATOM   9584  C CD   . GLU B 1 294 ? 1.266   26.919  64.282 1.00 21.54 ?  260  GLU B CD   1 
ATOM   9585  O OE1  . GLU B 1 294 ? 1.597   25.778  64.621 1.00 19.87 ?  260  GLU B OE1  1 
ATOM   9586  O OE2  . GLU B 1 294 ? 1.966   27.550  63.503 1.00 24.04 ?  260  GLU B OE2  1 
ATOM   9587  H H    . GLU B 1 294 ? -2.980  27.649  64.191 1.00 16.61 ?  260  GLU B H    1 
ATOM   9588  H HA   . GLU B 1 294 ? -1.436  29.647  64.951 1.00 17.94 ?  260  GLU B HA   1 
ATOM   9589  H HB2  . GLU B 1 294 ? -1.097  27.831  62.842 1.00 20.00 ?  260  GLU B HB2  1 
ATOM   9590  H HB3  . GLU B 1 294 ? -0.012  28.936  63.198 1.00 20.00 ?  260  GLU B HB3  1 
ATOM   9591  H HG2  . GLU B 1 294 ? -0.049  27.917  65.457 1.00 18.20 ?  260  GLU B HG2  1 
ATOM   9592  H HG3  . GLU B 1 294 ? -0.695  26.666  64.722 1.00 18.20 ?  260  GLU B HG3  1 
ATOM   9593  N N    . GLY B 1 295 ? -3.088  30.205  62.280 1.00 13.05 ?  261  GLY B N    1 
ATOM   9594  C CA   . GLY B 1 295 ? -3.521  31.293  61.416 1.00 12.52 ?  261  GLY B CA   1 
ATOM   9595  C C    . GLY B 1 295 ? -4.303  32.333  62.176 1.00 12.92 ?  261  GLY B C    1 
ATOM   9596  O O    . GLY B 1 295 ? -4.125  33.544  61.967 1.00 12.94 ?  261  GLY B O    1 
ATOM   9597  H H    . GLY B 1 295 ? -3.450  29.444  62.112 1.00 15.66 ?  261  GLY B H    1 
ATOM   9598  H HA2  . GLY B 1 295 ? -2.745  31.719  61.019 1.00 15.02 ?  261  GLY B HA2  1 
ATOM   9599  H HA3  . GLY B 1 295 ? -4.083  30.940  60.709 1.00 15.02 ?  261  GLY B HA3  1 
ATOM   9600  N N    . ILE B 1 296 ? -5.151  31.900  63.094 1.00 12.58 ?  262  ILE B N    1 
ATOM   9601  C CA   . ILE B 1 296 ? -5.913  32.818  63.925 1.00 13.41 ?  262  ILE B CA   1 
ATOM   9602  C C    . ILE B 1 296 ? -4.966  33.689  64.745 1.00 12.59 ?  262  ILE B C    1 
ATOM   9603  O O    . ILE B 1 296 ? -5.140  34.894  64.873 1.00 13.65 ?  262  ILE B O    1 
ATOM   9604  C CB   . ILE B 1 296 ? -6.892  32.022  64.817 1.00 12.80 ?  262  ILE B CB   1 
ATOM   9605  C CG1  . ILE B 1 296 ? -8.049  31.497  63.948 1.00 14.63 ?  262  ILE B CG1  1 
ATOM   9606  C CG2  . ILE B 1 296 ? -7.376  32.843  65.984 1.00 14.71 ?  262  ILE B CG2  1 
ATOM   9607  C CD1  . ILE B 1 296 ? -8.840  30.398  64.621 1.00 15.38 ?  262  ILE B CD1  1 
ATOM   9608  H H    . ILE B 1 296 ? -5.307  31.071  63.259 1.00 15.10 ?  262  ILE B H    1 
ATOM   9609  H HA   . ILE B 1 296 ? -6.437  33.407  63.359 1.00 16.09 ?  262  ILE B HA   1 
ATOM   9610  H HB   . ILE B 1 296 ? -6.425  31.264  65.202 1.00 15.37 ?  262  ILE B HB   1 
ATOM   9611  H HG12 . ILE B 1 296 ? -8.656  32.229  63.756 1.00 17.56 ?  262  ILE B HG12 1 
ATOM   9612  H HG13 . ILE B 1 296 ? -7.686  31.142  63.122 1.00 17.56 ?  262  ILE B HG13 1 
ATOM   9613  H HG21 . ILE B 1 296 ? -8.071  32.351  66.449 1.00 17.66 ?  262  ILE B HG21 1 
ATOM   9614  H HG22 . ILE B 1 296 ? -6.632  33.009  66.583 1.00 17.66 ?  262  ILE B HG22 1 
ATOM   9615  H HG23 . ILE B 1 296 ? -7.730  33.683  65.654 1.00 17.66 ?  262  ILE B HG23 1 
ATOM   9616  H HD11 . ILE B 1 296 ? -9.459  30.017  63.979 1.00 18.46 ?  262  ILE B HD11 1 
ATOM   9617  H HD12 . ILE B 1 296 ? -8.227  29.715  64.936 1.00 18.46 ?  262  ILE B HD12 1 
ATOM   9618  H HD13 . ILE B 1 296 ? -9.329  30.775  65.369 1.00 18.46 ?  262  ILE B HD13 1 
ATOM   9619  N N    . GLU B 1 297 ? -3.940  33.074  65.346 1.00 14.66 ?  263  GLU B N    1 
ATOM   9620  C CA   . GLU B 1 297 ? -2.997  33.832  66.163 1.00 14.16 ?  263  GLU B CA   1 
ATOM   9621  C C    . GLU B 1 297 ? -2.264  34.878  65.331 1.00 13.56 ?  263  GLU B C    1 
ATOM   9622  O O    . GLU B 1 297 ? -2.143  36.036  65.743 1.00 14.17 ?  263  GLU B O    1 
ATOM   9623  C CB   . GLU B 1 297 ? -2.033  32.858  66.865 1.00 16.46 ?  263  GLU B CB   1 
ATOM   9624  C CG   . GLU B 1 297 ? -2.668  32.219  68.112 1.00 25.46 ?  263  GLU B CG   1 
ATOM   9625  C CD   . GLU B 1 297 ? -1.971  30.954  68.681 1.00 46.98 ?  263  GLU B CD   1 
ATOM   9626  O OE1  . GLU B 1 297 ? -0.931  30.442  68.128 1.00 26.89 ?  263  GLU B OE1  1 
ATOM   9627  O OE2  . GLU B 1 297 ? -2.506  30.484  69.735 1.00 27.85 ?  263  GLU B OE2  1 
ATOM   9628  H H    . GLU B 1 297 ? -3.774  32.232  65.296 1.00 17.60 ?  263  GLU B H    1 
ATOM   9629  H HA   . GLU B 1 297 ? -3.473  34.316  66.857 1.00 16.99 ?  263  GLU B HA   1 
ATOM   9630  H HB2  . GLU B 1 297 ? -1.793  32.148  66.249 1.00 19.75 ?  263  GLU B HB2  1 
ATOM   9631  H HB3  . GLU B 1 297 ? -1.238  33.340  67.142 1.00 19.75 ?  263  GLU B HB3  1 
ATOM   9632  H HG2  . GLU B 1 297 ? -2.672  32.882  68.820 1.00 30.55 ?  263  GLU B HG2  1 
ATOM   9633  H HG3  . GLU B 1 297 ? -3.577  31.965  67.889 1.00 30.55 ?  263  GLU B HG3  1 
ATOM   9634  N N    . ALA B 1 298 ? -1.827  34.510  64.131 1.00 13.75 ?  264  ALA B N    1 
ATOM   9635  C CA   . ALA B 1 298 ? -1.161  35.476  63.262 1.00 12.72 ?  264  ALA B CA   1 
ATOM   9636  C C    . ALA B 1 298 ? -2.099  36.617  62.906 1.00 12.76 ?  264  ALA B C    1 
ATOM   9637  O O    . ALA B 1 298 ? -1.718  37.798  62.903 1.00 14.47 ?  264  ALA B O    1 
ATOM   9638  C CB   . ALA B 1 298 ? -0.624  34.806  62.013 1.00 13.99 ?  264  ALA B CB   1 
ATOM   9639  H H    . ALA B 1 298 ? -1.902  33.719  63.800 1.00 16.50 ?  264  ALA B H    1 
ATOM   9640  H HA   . ALA B 1 298 ? -0.398  35.842  63.736 1.00 15.27 ?  264  ALA B HA   1 
ATOM   9641  H HB1  . ALA B 1 298 ? -0.167  35.468  61.471 1.00 16.79 ?  264  ALA B HB1  1 
ATOM   9642  H HB2  . ALA B 1 298 ? -0.003  34.106  62.272 1.00 16.79 ?  264  ALA B HB2  1 
ATOM   9643  H HB3  . ALA B 1 298 ? -1.364  34.424  61.516 1.00 16.79 ?  264  ALA B HB3  1 
ATOM   9644  N N    . THR B 1 299 ? -3.335  36.271  62.551 1.00 13.13 ?  265  THR B N    1 
ATOM   9645  C CA   . THR B 1 299 ? -4.281  37.272  62.085 1.00 13.27 ?  265  THR B CA   1 
ATOM   9646  C C    . THR B 1 299 ? -4.673  38.209  63.205 1.00 12.65 ?  265  THR B C    1 
ATOM   9647  O O    . THR B 1 299 ? -4.745  39.431  63.010 1.00 14.25 ?  265  THR B O    1 
ATOM   9648  C CB   . THR B 1 299 ? -5.508  36.568  61.490 1.00 13.19 ?  265  THR B CB   1 
ATOM   9649  O OG1  . THR B 1 299 ? -5.077  35.720  60.414 1.00 13.50 ?  265  THR B OG1  1 
ATOM   9650  C CG2  . THR B 1 299 ? -6.461  37.582  60.927 1.00 13.45 ?  265  THR B CG2  1 
ATOM   9651  H H    . THR B 1 299 ? -3.646  35.469  62.572 1.00 15.75 ?  265  THR B H    1 
ATOM   9652  H HA   . THR B 1 299 ? -3.875  37.809  61.387 1.00 15.92 ?  265  THR B HA   1 
ATOM   9653  H HB   . THR B 1 299 ? -5.956  36.051  62.178 1.00 15.83 ?  265  THR B HB   1 
ATOM   9654  H HG1  . THR B 1 299 ? -4.655  35.060  60.718 1.00 16.20 ?  265  THR B HG1  1 
ATOM   9655  H HG21 . THR B 1 299 ? -7.239  37.137  60.556 1.00 16.14 ?  265  THR B HG21 1 
ATOM   9656  H HG22 . THR B 1 299 ? -6.750  38.190  61.625 1.00 16.14 ?  265  THR B HG22 1 
ATOM   9657  H HG23 . THR B 1 299 ? -6.027  38.093  60.225 1.00 16.14 ?  265  THR B HG23 1 
ATOM   9658  N N    . GLN B 1 300 ? -4.926  37.667  64.400 1.00 13.47 ?  266  GLN B N    1 
ATOM   9659  C CA   . GLN B 1 300 ? -5.222  38.512  65.555 1.00 14.00 ?  266  GLN B CA   1 
ATOM   9660  C C    . GLN B 1 300 ? -4.107  39.522  65.812 1.00 14.63 ?  266  GLN B C    1 
ATOM   9661  O O    . GLN B 1 300 ? -4.366  40.699  66.084 1.00 14.99 ?  266  GLN B O    1 
ATOM   9662  C CB   . GLN B 1 300 ? -5.408  37.653  66.801 1.00 15.44 ?  266  GLN B CB   1 
ATOM   9663  C CG   . GLN B 1 300 ? -6.743  36.929  66.799 1.00 14.04 ?  266  GLN B CG   1 
ATOM   9664  C CD   . GLN B 1 300 ? -6.873  35.898  67.903 1.00 16.69 ?  266  GLN B CD   1 
ATOM   9665  O OE1  . GLN B 1 300 ? -5.870  35.381  68.425 1.00 17.50 ?  266  GLN B OE1  1 
ATOM   9666  N NE2  . GLN B 1 300 ? -8.124  35.514  68.214 1.00 18.54 ?  266  GLN B NE2  1 
ATOM   9667  H H    . GLN B 1 300 ? -4.932  36.823  64.565 1.00 16.16 ?  266  GLN B H    1 
ATOM   9668  H HA   . GLN B 1 300 ? -6.045  38.991  65.368 1.00 16.80 ?  266  GLN B HA   1 
ATOM   9669  H HB2  . GLN B 1 300 ? -4.703  36.988  66.838 1.00 18.53 ?  266  GLN B HB2  1 
ATOM   9670  H HB3  . GLN B 1 300 ? -5.372  38.220  67.587 1.00 18.53 ?  266  GLN B HB3  1 
ATOM   9671  H HG2  . GLN B 1 300 ? -7.452  37.580  66.916 1.00 16.85 ?  266  GLN B HG2  1 
ATOM   9672  H HG3  . GLN B 1 300 ? -6.849  36.471  65.951 1.00 16.85 ?  266  GLN B HG3  1 
ATOM   9673  H HE21 . GLN B 1 300 ? -8.795  35.852  67.794 1.00 22.25 ?  266  GLN B HE21 1 
ATOM   9674  H HE22 . GLN B 1 300 ? -8.254  34.932  68.833 1.00 22.25 ?  266  GLN B HE22 1 
ATOM   9675  N N    . LYS B 1 301 ? -2.865  39.069  65.787 1.00 15.00 ?  267  LYS B N    1 
ATOM   9676  C CA   . LYS B 1 301 ? -1.750  39.972  66.069 1.00 15.02 ?  267  LYS B CA   1 
ATOM   9677  C C    . LYS B 1 301 ? -1.698  41.069  65.021 1.00 15.11 ?  267  LYS B C    1 
ATOM   9678  O O    . LYS B 1 301 ? -1.551  42.254  65.327 1.00 14.36 ?  267  LYS B O    1 
ATOM   9679  C CB   . LYS B 1 301 ? -0.446  39.181  66.096 1.00 17.57 ?  267  LYS B CB   1 
ATOM   9680  C CG   . LYS B 1 301 ? 0.730   39.914  66.701 1.00 31.21 ?  267  LYS B CG   1 
ATOM   9681  C CD   . LYS B 1 301 ? 1.722   38.912  67.317 1.00 30.88 ?  267  LYS B CD   1 
ATOM   9682  C CE   . LYS B 1 301 ? 3.146   39.475  67.395 1.00 47.57 ?  267  LYS B CE   1 
ATOM   9683  N NZ   . LYS B 1 301 ? 3.929   38.825  68.495 1.00 39.94 ?  267  LYS B NZ   1 
ATOM   9684  H H    . LYS B 1 301 ? -2.638  38.258  65.614 1.00 18.00 ?  267  LYS B H    1 
ATOM   9685  H HA   . LYS B 1 301 ? -1.867  40.383  66.940 1.00 18.03 ?  267  LYS B HA   1 
ATOM   9686  H HB2  . LYS B 1 301 ? -0.586  38.375  66.617 1.00 21.09 ?  267  LYS B HB2  1 
ATOM   9687  H HB3  . LYS B 1 301 ? -0.207  38.950  65.185 1.00 21.09 ?  267  LYS B HB3  1 
ATOM   9688  H HG2  . LYS B 1 301 ? 1.188   40.420  66.013 1.00 37.45 ?  267  LYS B HG2  1 
ATOM   9689  H HG3  . LYS B 1 301 ? 0.418   40.510  67.400 1.00 37.45 ?  267  LYS B HG3  1 
ATOM   9690  H HD2  . LYS B 1 301 ? 1.436   38.692  68.217 1.00 37.05 ?  267  LYS B HD2  1 
ATOM   9691  H HD3  . LYS B 1 301 ? 1.745   38.110  66.771 1.00 37.05 ?  267  LYS B HD3  1 
ATOM   9692  H HE2  . LYS B 1 301 ? 3.603   39.312  66.555 1.00 57.09 ?  267  LYS B HE2  1 
ATOM   9693  H HE3  . LYS B 1 301 ? 3.105   40.429  67.570 1.00 57.09 ?  267  LYS B HE3  1 
ATOM   9694  H HZ1  . LYS B 1 301 ? 4.747   39.173  68.533 1.00 47.93 ?  267  LYS B HZ1  1 
ATOM   9695  H HZ2  . LYS B 1 301 ? 3.523   38.955  69.276 1.00 47.93 ?  267  LYS B HZ2  1 
ATOM   9696  H HZ3  . LYS B 1 301 ? 3.995   37.950  68.346 1.00 47.93 ?  267  LYS B HZ3  1 
ATOM   9697  N N    . ALA B 1 302 ? -1.824  40.692  63.744 1.00 14.48 ?  268  ALA B N    1 
ATOM   9698  C CA   . ALA B 1 302 ? -1.791  41.689  62.677 1.00 14.11 ?  268  ALA B CA   1 
ATOM   9699  C C    . ALA B 1 302 ? -2.925  42.700  62.822 1.00 13.63 ?  268  ALA B C    1 
ATOM   9700  O O    . ALA B 1 302 ? -2.726  43.928  62.770 1.00 13.69 ?  268  ALA B O    1 
ATOM   9701  C CB   . ALA B 1 302 ? -1.862  40.972  61.326 1.00 14.09 ?  268  ALA B CB   1 
ATOM   9702  H H    . ALA B 1 302 ? -1.928  39.881  63.476 1.00 17.38 ?  268  ALA B H    1 
ATOM   9703  H HA   . ALA B 1 302 ? -0.958  42.184  62.724 1.00 16.93 ?  268  ALA B HA   1 
ATOM   9704  H HB1  . ALA B 1 302 ? -1.818  41.631  60.616 1.00 16.91 ?  268  ALA B HB1  1 
ATOM   9705  H HB2  . ALA B 1 302 ? -1.113  40.358  61.254 1.00 16.91 ?  268  ALA B HB2  1 
ATOM   9706  H HB3  . ALA B 1 302 ? -2.697  40.482  61.272 1.00 16.91 ?  268  ALA B HB3  1 
ATOM   9707  N N    . ALA B 1 303 ? -4.154  42.205  62.961 1.00 13.08 ?  269  ALA B N    1 
ATOM   9708  C CA   . ALA B 1 303 ? -5.306  43.089  63.067 1.00 13.43 ?  269  ALA B CA   1 
ATOM   9709  C C    . ALA B 1 303 ? -5.208  44.009  64.278 1.00 13.39 ?  269  ALA B C    1 
ATOM   9710  O O    . ALA B 1 303 ? -5.551  45.209  64.208 1.00 15.03 ?  269  ALA B O    1 
ATOM   9711  C CB   . ALA B 1 303 ? -6.597  42.263  63.102 1.00 14.89 ?  269  ALA B CB   1 
ATOM   9712  H H    . ALA B 1 303 ? -4.345  41.368  62.995 1.00 15.69 ?  269  ALA B H    1 
ATOM   9713  H HA   . ALA B 1 303 ? -5.334  43.657  62.281 1.00 16.11 ?  269  ALA B HA   1 
ATOM   9714  H HB1  . ALA B 1 303 ? -7.356  42.865  63.152 1.00 17.87 ?  269  ALA B HB1  1 
ATOM   9715  H HB2  . ALA B 1 303 ? -6.653  41.729  62.294 1.00 17.87 ?  269  ALA B HB2  1 
ATOM   9716  H HB3  . ALA B 1 303 ? -6.582  41.685  63.880 1.00 17.87 ?  269  ALA B HB3  1 
ATOM   9717  N N    . GLN B 1 304 ? -4.727  43.476  65.401 1.00 15.09 ?  270  GLN B N    1 
ATOM   9718  C CA   . GLN B 1 304 ? -4.638  44.274  66.617 1.00 16.01 ?  270  GLN B CA   1 
ATOM   9719  C C    . GLN B 1 304 ? -3.558  45.342  66.499 1.00 17.22 ?  270  GLN B C    1 
ATOM   9720  O O    . GLN B 1 304 ? -3.645  46.364  67.192 1.00 19.96 ?  270  GLN B O    1 
ATOM   9721  C CB   . GLN B 1 304 ? -4.424  43.384  67.837 1.00 15.62 ?  270  GLN B CB   1 
ATOM   9722  C CG   . GLN B 1 304 ? -5.652  42.536  68.169 1.00 17.00 ?  270  GLN B CG   1 
ATOM   9723  C CD   . GLN B 1 304 ? -5.367  41.392  69.121 1.00 18.67 ?  270  GLN B CD   1 
ATOM   9724  O OE1  . GLN B 1 304 ? -4.380  41.428  69.881 1.00 22.75 ?  270  GLN B OE1  1 
ATOM   9725  N NE2  . GLN B 1 304 ? -6.220  40.414  69.118 1.00 17.18 ?  270  GLN B NE2  1 
ATOM   9726  H H    . GLN B 1 304 ? -4.451  42.665  65.482 1.00 18.11 ?  270  GLN B H    1 
ATOM   9727  H HA   . GLN B 1 304 ? -5.481  44.727  66.770 1.00 19.22 ?  270  GLN B HA   1 
ATOM   9728  H HB2  . GLN B 1 304 ? -3.681  42.784  67.665 1.00 18.75 ?  270  GLN B HB2  1 
ATOM   9729  H HB3  . GLN B 1 304 ? -4.228  43.943  68.606 1.00 18.75 ?  270  GLN B HB3  1 
ATOM   9730  H HG2  . GLN B 1 304 ? -6.321  43.104  68.581 1.00 20.39 ?  270  GLN B HG2  1 
ATOM   9731  H HG3  . GLN B 1 304 ? -6.000  42.156  67.347 1.00 20.39 ?  270  GLN B HG3  1 
ATOM   9732  H HE21 . GLN B 1 304 ? -6.901  40.440  68.594 1.00 20.61 ?  270  GLN B HE21 1 
ATOM   9733  H HE22 . GLN B 1 304 ? -6.104  39.741  69.640 1.00 20.61 ?  270  GLN B HE22 1 
ATOM   9734  N N    . SER B 1 305 ? -2.620  45.180  65.576 1.00 14.52 ?  271  SER B N    1 
ATOM   9735  C CA   . SER B 1 305 ? -1.593  46.187  65.313 1.00 15.79 ?  271  SER B CA   1 
ATOM   9736  C C    . SER B 1 305 ? -2.051  47.275  64.361 1.00 16.31 ?  271  SER B C    1 
ATOM   9737  O O    . SER B 1 305 ? -1.287  48.223  64.106 1.00 18.09 ?  271  SER B O    1 
ATOM   9738  C CB   . SER B 1 305 ? -0.325  45.523  64.782 1.00 15.79 ?  271  SER B CB   1 
ATOM   9739  O OG   . SER B 1 305 ? -0.412  45.182  63.394 1.00 17.52 ?  271  SER B OG   1 
ATOM   9740  H H    . SER B 1 305 ? -2.553  44.483  65.076 1.00 17.42 ?  271  SER B H    1 
ATOM   9741  H HA   . SER B 1 305 ? -1.366  46.617  66.152 1.00 18.95 ?  271  SER B HA   1 
ATOM   9742  H HB2  . SER B 1 305 ? 0.416   46.137  64.902 1.00 18.95 ?  271  SER B HB2  1 
ATOM   9743  H HB3  . SER B 1 305 ? -0.169  44.711  65.289 1.00 18.95 ?  271  SER B HB3  1 
ATOM   9744  H HG   . SER B 1 305 ? -1.208  45.004  63.192 1.00 21.03 ?  271  SER B HG   1 
ATOM   9745  N N    . GLY B 1 306 ? -3.262  47.155  63.813 1.00 15.28 ?  272  GLY B N    1 
ATOM   9746  C CA   . GLY B 1 306 ? -3.810  48.148  62.924 1.00 14.66 ?  272  GLY B CA   1 
ATOM   9747  C C    . GLY B 1 306 ? -3.658  47.831  61.459 1.00 13.65 ?  272  GLY B C    1 
ATOM   9748  O O    . GLY B 1 306 ? -3.932  48.707  60.630 1.00 16.38 ?  272  GLY B O    1 
ATOM   9749  H H    . GLY B 1 306 ? -3.788  46.489  63.952 1.00 18.33 ?  272  GLY B H    1 
ATOM   9750  H HA2  . GLY B 1 306 ? -4.757  48.244  63.110 1.00 17.59 ?  272  GLY B HA2  1 
ATOM   9751  H HA3  . GLY B 1 306 ? -3.367  48.994  63.092 1.00 17.59 ?  272  GLY B HA3  1 
ATOM   9752  N N    . LYS B 1 307 ? -3.188  46.648  61.109 1.00 13.62 ?  273  LYS B N    1 
ATOM   9753  C CA   . LYS B 1 307 ? -3.086  46.238  59.716 1.00 14.31 ?  273  LYS B CA   1 
ATOM   9754  C C    . LYS B 1 307 ? -4.462  45.820  59.175 1.00 12.72 ?  273  LYS B C    1 
ATOM   9755  O O    . LYS B 1 307 ? -5.266  45.210  59.891 1.00 13.88 ?  273  LYS B O    1 
ATOM   9756  C CB   . LYS B 1 307 ? -2.130  45.062  59.567 1.00 15.06 ?  273  LYS B CB   1 
ATOM   9757  C CG   . LYS B 1 307 ? -0.681  45.351  60.003 1.00 15.93 ?  273  LYS B CG   1 
ATOM   9758  C CD   . LYS B 1 307 ? 0.048   46.173  58.963 1.00 17.44 ?  273  LYS B CD   1 
ATOM   9759  C CE   . LYS B 1 307 ? 1.504   46.365  59.412 1.00 20.44 ?  273  LYS B CE   1 
ATOM   9760  N NZ   . LYS B 1 307 ? 2.219   47.275  58.489 1.00 23.08 ?  273  LYS B NZ   1 
ATOM   9761  H H    . LYS B 1 307 ? -2.917  46.052  61.667 1.00 16.35 ?  273  LYS B H    1 
ATOM   9762  H HA   . LYS B 1 307 ? -2.749  46.986  59.198 1.00 17.18 ?  273  LYS B HA   1 
ATOM   9763  H HB2  . LYS B 1 307 ? -2.457  44.328  60.110 1.00 18.07 ?  273  LYS B HB2  1 
ATOM   9764  H HB3  . LYS B 1 307 ? -2.108  44.799  58.633 1.00 18.07 ?  273  LYS B HB3  1 
ATOM   9765  H HG2  . LYS B 1 307 ? -0.687  45.847  60.836 1.00 19.11 ?  273  LYS B HG2  1 
ATOM   9766  H HG3  . LYS B 1 307 ? -0.206  44.513  60.119 1.00 19.11 ?  273  LYS B HG3  1 
ATOM   9767  H HD2  . LYS B 1 307 ? 0.039   45.712  58.110 1.00 20.93 ?  273  LYS B HD2  1 
ATOM   9768  H HD3  . LYS B 1 307 ? -0.372  47.043  58.874 1.00 20.93 ?  273  LYS B HD3  1 
ATOM   9769  H HE2  . LYS B 1 307 ? 1.521   46.751  60.302 1.00 24.53 ?  273  LYS B HE2  1 
ATOM   9770  H HE3  . LYS B 1 307 ? 1.959   45.508  59.414 1.00 24.53 ?  273  LYS B HE3  1 
ATOM   9771  H HZ1  . LYS B 1 307 ? 2.257   46.915  57.676 1.00 27.70 ?  273  LYS B HZ1  1 
ATOM   9772  H HZ2  . LYS B 1 307 ? 1.793   48.055  58.441 1.00 27.70 ?  273  LYS B HZ2  1 
ATOM   9773  H HZ3  . LYS B 1 307 ? 3.048   47.415  58.782 1.00 27.70 ?  273  LYS B HZ3  1 
ATOM   9774  N N    . ILE B 1 308 ? -4.698  46.135  57.895 1.00 12.67 ?  274  ILE B N    1 
ATOM   9775  C CA   . ILE B 1 308 ? -5.888  45.646  57.200 1.00 11.89 ?  274  ILE B CA   1 
ATOM   9776  C C    . ILE B 1 308 ? -5.818  44.129  57.058 1.00 12.30 ?  274  ILE B C    1 
ATOM   9777  O O    . ILE B 1 308 ? -4.744  43.566  56.778 1.00 13.12 ?  274  ILE B O    1 
ATOM   9778  C CB   . ILE B 1 308 ? -5.995  46.330  55.826 1.00 12.82 ?  274  ILE B CB   1 
ATOM   9779  C CG1  . ILE B 1 308 ? -6.168  47.841  55.996 1.00 15.70 ?  274  ILE B CG1  1 
ATOM   9780  C CG2  . ILE B 1 308 ? -7.150  45.713  55.009 1.00 12.83 ?  274  ILE B CG2  1 
ATOM   9781  C CD1  . ILE B 1 308 ? -5.913  48.658  54.702 1.00 15.58 ?  274  ILE B CD1  1 
ATOM   9782  H H    . ILE B 1 308 ? -4.185  46.627  57.411 1.00 15.21 ?  274  ILE B H    1 
ATOM   9783  H HA   . ILE B 1 308 ? -6.679  45.860  57.720 1.00 14.27 ?  274  ILE B HA   1 
ATOM   9784  H HB   . ILE B 1 308 ? -5.172  46.180  55.336 1.00 15.39 ?  274  ILE B HB   1 
ATOM   9785  H HG12 . ILE B 1 308 ? -7.078  48.019  56.282 1.00 18.84 ?  274  ILE B HG12 1 
ATOM   9786  H HG13 . ILE B 1 308 ? -5.542  48.151  56.668 1.00 18.84 ?  274  ILE B HG13 1 
ATOM   9787  H HG21 . ILE B 1 308 ? -7.289  46.243  54.209 1.00 15.40 ?  274  ILE B HG21 1 
ATOM   9788  H HG22 . ILE B 1 308 ? -6.915  44.804  54.766 1.00 15.40 ?  274  ILE B HG22 1 
ATOM   9789  H HG23 . ILE B 1 308 ? -7.955  45.713  55.550 1.00 15.40 ?  274  ILE B HG23 1 
ATOM   9790  H HD11 . ILE B 1 308 ? -5.852  49.599  54.930 1.00 18.70 ?  274  ILE B HD11 1 
ATOM   9791  H HD12 . ILE B 1 308 ? -5.082  48.361  54.299 1.00 18.70 ?  274  ILE B HD12 1 
ATOM   9792  H HD13 . ILE B 1 308 ? -6.649  48.514  54.087 1.00 18.70 ?  274  ILE B HD13 1 
ATOM   9793  N N    . ILE B 1 309 ? -6.963  43.462  57.262 1.00 12.39 ?  275  ILE B N    1 
ATOM   9794  C CA   . ILE B 1 309 ? -7.099  42.039  56.985 1.00 11.36 ?  275  ILE B CA   1 
ATOM   9795  C C    . ILE B 1 309 ? -8.259  41.859  56.033 1.00 11.70 ?  275  ILE B C    1 
ATOM   9796  O O    . ILE B 1 309 ? -9.369  42.348  56.292 1.00 11.92 ?  275  ILE B O    1 
ATOM   9797  C CB   . ILE B 1 309 ? -7.344  41.221  58.274 1.00 10.87 ?  275  ILE B CB   1 
ATOM   9798  C CG1  . ILE B 1 309 ? -6.114  41.242  59.198 1.00 12.89 ?  275  ILE B CG1  1 
ATOM   9799  C CG2  . ILE B 1 309 ? -7.767  39.787  57.949 1.00 12.50 ?  275  ILE B CG2  1 
ATOM   9800  C CD1  . ILE B 1 309 ? -4.880  40.581  58.626 1.00 14.50 ?  275  ILE B CD1  1 
ATOM   9801  H H    . ILE B 1 309 ? -7.682  43.825  57.566 1.00 14.87 ?  275  ILE B H    1 
ATOM   9802  H HA   . ILE B 1 309 ? -6.285  41.719  56.565 1.00 13.63 ?  275  ILE B HA   1 
ATOM   9803  H HB   . ILE B 1 309 ? -8.075  41.646  58.750 1.00 13.05 ?  275  ILE B HB   1 
ATOM   9804  H HG12 . ILE B 1 309 ? -5.888  42.166  59.388 1.00 15.47 ?  275  ILE B HG12 1 
ATOM   9805  H HG13 . ILE B 1 309 ? -6.338  40.780  60.020 1.00 15.47 ?  275  ILE B HG13 1 
ATOM   9806  H HG21 . ILE B 1 309 ? -7.805  39.275  58.772 1.00 15.00 ?  275  ILE B HG21 1 
ATOM   9807  H HG22 . ILE B 1 309 ? -8.641  39.803  57.529 1.00 15.00 ?  275  ILE B HG22 1 
ATOM   9808  H HG23 . ILE B 1 309 ? -7.117  39.395  57.345 1.00 15.00 ?  275  ILE B HG23 1 
ATOM   9809  H HD11 . ILE B 1 309 ? -4.166  40.625  59.281 1.00 17.40 ?  275  ILE B HD11 1 
ATOM   9810  H HD12 . ILE B 1 309 ? -5.085  39.655  58.421 1.00 17.40 ?  275  ILE B HD12 1 
ATOM   9811  H HD13 . ILE B 1 309 ? -4.617  41.048  57.818 1.00 17.40 ?  275  ILE B HD13 1 
ATOM   9812  N N    . THR B 1 310 ? -8.022  41.108  54.951 1.00 10.71 ?  276  THR B N    1 
ATOM   9813  C CA   . THR B 1 310 ? -9.101  40.686  54.065 1.00 11.68 ?  276  THR B CA   1 
ATOM   9814  C C    . THR B 1 310 ? -9.113  39.153  54.064 1.00 11.52 ?  276  THR B C    1 
ATOM   9815  O O    . THR B 1 310 ? -8.332  38.505  53.350 1.00 12.20 ?  276  THR B O    1 
ATOM   9816  C CB   . THR B 1 310 ? -8.994  41.311  52.654 1.00 11.62 ?  276  THR B CB   1 
ATOM   9817  O OG1  . THR B 1 310 ? -7.830  40.857  51.956 1.00 12.39 ?  276  THR B OG1  1 
ATOM   9818  C CG2  . THR B 1 310 ? -8.948  42.820  52.713 1.00 12.63 ?  276  THR B CG2  1 
ATOM   9819  H H    . THR B 1 310 ? -7.242  40.833  54.715 1.00 12.85 ?  276  THR B H    1 
ATOM   9820  H HA   . THR B 1 310 ? -9.951  40.992  54.418 1.00 14.02 ?  276  THR B HA   1 
ATOM   9821  H HB   . THR B 1 310 ? -9.785  41.035  52.167 1.00 13.94 ?  276  THR B HB   1 
ATOM   9822  H HG1  . THR B 1 310 ? -7.969  40.095  51.632 1.00 14.86 ?  276  THR B HG1  1 
ATOM   9823  H HG21 . THR B 1 310 ? -8.903  43.186  51.815 1.00 15.15 ?  276  THR B HG21 1 
ATOM   9824  H HG22 . THR B 1 310 ? -9.744  43.160  53.151 1.00 15.15 ?  276  THR B HG22 1 
ATOM   9825  H HG23 . THR B 1 310 ? -8.167  43.110  53.210 1.00 15.15 ?  276  THR B HG23 1 
ATOM   9826  N N    . MET B 1 311 ? -9.981  38.569  54.870 1.00 11.11 ?  277  MET B N    1 
ATOM   9827  C CA   . MET B 1 311 ? -10.029 37.126  55.022 1.00 11.24 ?  277  MET B CA   1 
ATOM   9828  C C    . MET B 1 311 ? -10.947 36.529  53.987 1.00 11.16 ?  277  MET B C    1 
ATOM   9829  O O    . MET B 1 311 ? -12.139 36.840  53.964 1.00 12.52 ?  277  MET B O    1 
ATOM   9830  C CB   . MET B 1 311 ? -10.532 36.745  56.410 1.00 13.08 ?  277  MET B CB   1 
ATOM   9831  C CG   . MET B 1 311 ? -10.497 35.256  56.684 1.00 12.56 ?  277  MET B CG   1 
ATOM   9832  S SD   . MET B 1 311 ? -11.065 34.750  58.309 1.00 13.15 ?  277  MET B SD   1 
ATOM   9833  C CE   . MET B 1 311 ? -9.720  35.296  59.326 1.00 14.01 ?  277  MET B CE   1 
ATOM   9834  H H    . MET B 1 311 ? -10.560 38.991  55.345 1.00 13.34 ?  277  MET B H    1 
ATOM   9835  H HA   . MET B 1 311 ? -9.130  36.783  54.902 1.00 13.49 ?  277  MET B HA   1 
ATOM   9836  H HB2  . MET B 1 311 ? -9.975  37.182  57.074 1.00 15.70 ?  277  MET B HB2  1 
ATOM   9837  H HB3  . MET B 1 311 ? -11.451 37.042  56.500 1.00 15.70 ?  277  MET B HB3  1 
ATOM   9838  H HG2  . MET B 1 311 ? -11.062 34.812  56.032 1.00 15.07 ?  277  MET B HG2  1 
ATOM   9839  H HG3  . MET B 1 311 ? -9.581  34.950  56.592 1.00 15.07 ?  277  MET B HG3  1 
ATOM   9840  H HE1  . MET B 1 311 ? -9.926  35.099  60.253 1.00 16.81 ?  277  MET B HE1  1 
ATOM   9841  H HE2  . MET B 1 311 ? -8.913  34.829  59.060 1.00 16.81 ?  277  MET B HE2  1 
ATOM   9842  H HE3  . MET B 1 311 ? -9.604  36.252  59.209 1.00 16.81 ?  277  MET B HE3  1 
ATOM   9843  N N    . THR B 1 312 ? -10.390 35.700  53.108 1.00 10.86 ?  278  THR B N    1 
ATOM   9844  C CA   . THR B 1 312 ? -11.203 34.937  52.156 1.00 11.43 ?  278  THR B CA   1 
ATOM   9845  C C    . THR B 1 312 ? -11.307 33.497  52.631 1.00 11.88 ?  278  THR B C    1 
ATOM   9846  O O    . THR B 1 312 ? -10.317 32.912  53.091 1.00 12.55 ?  278  THR B O    1 
ATOM   9847  C CB   . THR B 1 312 ? -10.679 35.045  50.705 1.00 12.06 ?  278  THR B CB   1 
ATOM   9848  O OG1  . THR B 1 312 ? -9.461  34.300  50.499 1.00 12.30 ?  278  THR B OG1  1 
ATOM   9849  C CG2  . THR B 1 312 ? -10.475 36.504  50.337 1.00 13.48 ?  278  THR B CG2  1 
ATOM   9850  H H    . THR B 1 312 ? -9.545  35.560  53.041 1.00 13.03 ?  278  THR B H    1 
ATOM   9851  H HA   . THR B 1 312 ? -12.101 35.303  52.122 1.00 13.72 ?  278  THR B HA   1 
ATOM   9852  H HB   . THR B 1 312 ? -11.342 34.655  50.113 1.00 14.47 ?  278  THR B HB   1 
ATOM   9853  H HG1  . THR B 1 312 ? -8.891  34.514  51.077 1.00 14.77 ?  278  THR B HG1  1 
ATOM   9854  H HG21 . THR B 1 312 ? -10.324 36.587  49.382 1.00 16.18 ?  278  THR B HG21 1 
ATOM   9855  H HG22 . THR B 1 312 ? -11.261 37.019  50.577 1.00 16.18 ?  278  THR B HG22 1 
ATOM   9856  H HG23 . THR B 1 312 ? -9.708  36.861  50.810 1.00 16.18 ?  278  THR B HG23 1 
ATOM   9857  N N    . LEU B 1 313 ? -12.505 32.931  52.544 1.00 11.69 ?  279  LEU B N    1 
ATOM   9858  C CA   . LEU B 1 313 ? -12.803 31.551  52.902 1.00 11.99 ?  279  LEU B CA   1 
ATOM   9859  C C    . LEU B 1 313 ? -13.728 30.980  51.846 1.00 12.04 ?  279  LEU B C    1 
ATOM   9860  O O    . LEU B 1 313 ? -14.756 31.588  51.518 1.00 11.65 ?  279  LEU B O    1 
ATOM   9861  C CB   . LEU B 1 313 ? -13.453 31.465  54.297 1.00 12.26 ?  279  LEU B CB   1 
ATOM   9862  C CG   . LEU B 1 313 ? -12.528 31.859  55.464 1.00 15.13 ?  279  LEU B CG   1 
ATOM   9863  C CD1  . LEU B 1 313 ? -13.342 32.178  56.708 1.00 15.91 ?  279  LEU B CD1  1 
ATOM   9864  C CD2  . LEU B 1 313 ? -11.485 30.783  55.736 1.00 19.51 ?  279  LEU B CD2  1 
ATOM   9865  H H    . LEU B 1 313 ? -13.202 33.350  52.265 1.00 14.03 ?  279  LEU B H    1 
ATOM   9866  H HA   . LEU B 1 313 ? -11.989 31.025  52.921 1.00 14.38 ?  279  LEU B HA   1 
ATOM   9867  H HB2  . LEU B 1 313 ? -14.219 32.060  54.317 1.00 14.71 ?  279  LEU B HB2  1 
ATOM   9868  H HB3  . LEU B 1 313 ? -13.740 30.550  54.447 1.00 14.71 ?  279  LEU B HB3  1 
ATOM   9869  H HG   . LEU B 1 313 ? -12.042 32.661  55.219 1.00 18.16 ?  279  LEU B HG   1 
ATOM   9870  H HD11 . LEU B 1 313 ? -12.737 32.368  57.442 1.00 19.09 ?  279  LEU B HD11 1 
ATOM   9871  H HD12 . LEU B 1 313 ? -13.900 32.952  56.531 1.00 19.09 ?  279  LEU B HD12 1 
ATOM   9872  H HD13 . LEU B 1 313 ? -13.898 31.414  56.927 1.00 19.09 ?  279  LEU B HD13 1 
ATOM   9873  H HD21 . LEU B 1 313 ? -10.912 31.075  56.461 1.00 23.41 ?  279  LEU B HD21 1 
ATOM   9874  H HD22 . LEU B 1 313 ? -11.937 29.960  55.982 1.00 23.41 ?  279  LEU B HD22 1 
ATOM   9875  H HD23 . LEU B 1 313 ? -10.959 30.644  54.933 1.00 23.41 ?  279  LEU B HD23 1 
ATOM   9876  N N    . GLY B 1 314 ? -13.376 29.820  51.311 1.00 12.81 ?  280  GLY B N    1 
ATOM   9877  C CA   . GLY B 1 314 ? -14.194 29.217  50.268 1.00 12.06 ?  280  GLY B CA   1 
ATOM   9878  C C    . GLY B 1 314 ? -15.399 28.515  50.839 1.00 14.22 ?  280  GLY B C    1 
ATOM   9879  O O    . GLY B 1 314 ? -15.306 27.771  51.822 1.00 16.49 ?  280  GLY B O    1 
ATOM   9880  H H    . GLY B 1 314 ? -12.678 29.367  51.529 1.00 15.37 ?  280  GLY B H    1 
ATOM   9881  H HA2  . GLY B 1 314 ? -14.500 29.906  49.657 1.00 14.47 ?  280  GLY B HA2  1 
ATOM   9882  H HA3  . GLY B 1 314 ? -13.666 28.570  49.775 1.00 14.47 ?  280  GLY B HA3  1 
ATOM   9883  N N    . LEU B 1 315 ? -16.537 28.719  50.190 1.00 13.82 ?  281  LEU B N    1 
ATOM   9884  C CA   . LEU B 1 315 ? -17.744 27.904  50.298 1.00 18.97 ?  281  LEU B CA   1 
ATOM   9885  C C    . LEU B 1 315 ? -17.848 26.907  49.148 1.00 23.52 ?  281  LEU B C    1 
ATOM   9886  O O    . LEU B 1 315 ? -18.840 26.164  49.069 1.00 24.40 ?  281  LEU B O    1 
ATOM   9887  C CB   . LEU B 1 315 ? -18.997 28.751  50.105 1.00 16.03 ?  281  LEU B CB   1 
ATOM   9888  C CG   . LEU B 1 315 ? -19.286 29.924  50.973 1.00 16.83 ?  281  LEU B CG   1 
ATOM   9889  C CD1  . LEU B 1 315 ? -20.315 30.778  50.260 1.00 26.29 ?  281  LEU B CD1  1 
ATOM   9890  C CD2  . LEU B 1 315 ? -19.786 29.439  52.306 1.00 25.66 ?  281  LEU B CD2  1 
ATOM   9891  H H    . LEU B 1 315 ? -16.645 29.371  49.639 1.00 16.58 ?  281  LEU B H    1 
ATOM   9892  H HA   . LEU B 1 315 ? -17.720 27.489  51.175 1.00 22.76 ?  281  LEU B HA   1 
ATOM   9893  H HB2  . LEU B 1 315 ? -18.965 29.097  49.199 1.00 19.24 ?  281  LEU B HB2  1 
ATOM   9894  H HB3  . LEU B 1 315 ? -19.757 28.156  50.206 1.00 19.24 ?  281  LEU B HB3  1 
ATOM   9895  H HG   . LEU B 1 315 ? -18.496 30.461  51.142 1.00 20.19 ?  281  LEU B HG   1 
ATOM   9896  H HD11 . LEU B 1 315 ? -20.521 31.550  50.810 1.00 31.55 ?  281  LEU B HD11 1 
ATOM   9897  H HD12 . LEU B 1 315 ? -19.950 31.067  49.409 1.00 31.55 ?  281  LEU B HD12 1 
ATOM   9898  H HD13 . LEU B 1 315 ? -21.116 30.252  50.115 1.00 31.55 ?  281  LEU B HD13 1 
ATOM   9899  H HD21 . LEU B 1 315 ? -19.982 30.206  52.867 1.00 30.80 ?  281  LEU B HD21 1 
ATOM   9900  H HD22 . LEU B 1 315 ? -20.591 28.915  52.169 1.00 30.80 ?  281  LEU B HD22 1 
ATOM   9901  H HD23 . LEU B 1 315 ? -19.101 28.892  52.720 1.00 30.80 ?  281  LEU B HD23 1 
ATOM   9902  N N    . GLY B 1 316 ? -16.865 26.864  48.242 1.00 30.95 ?  282  GLY B N    1 
ATOM   9903  C CA   . GLY B 1 316 ? -16.965 25.978  47.089 1.00 27.54 ?  282  GLY B CA   1 
ATOM   9904  C C    . GLY B 1 316 ? -17.328 24.549  47.445 1.00 33.60 ?  282  GLY B C    1 
ATOM   9905  O O    . GLY B 1 316 ? -18.114 23.907  46.739 1.00 36.28 ?  282  GLY B O    1 
ATOM   9906  H H    . GLY B 1 316 ? -16.144 27.331  48.275 1.00 37.13 ?  282  GLY B H    1 
ATOM   9907  H HA2  . GLY B 1 316 ? -17.645 26.319  46.487 1.00 33.04 ?  282  GLY B HA2  1 
ATOM   9908  H HA3  . GLY B 1 316 ? -16.112 25.964  46.627 1.00 33.04 ?  282  GLY B HA3  1 
ATOM   9909  N N    . GLU B 1 317 ? -16.778 24.033  48.554 1.00 34.04 ?  283  GLU B N    1 
ATOM   9910  C CA   . GLU B 1 317 ? -16.986 22.633  48.916 1.00 44.33 ?  283  GLU B CA   1 
ATOM   9911  C C    . GLU B 1 317 ? -18.345 22.400  49.552 1.00 45.06 ?  283  GLU B C    1 
ATOM   9912  O O    . GLU B 1 317 ? -18.887 21.304  49.442 1.00 34.85 ?  283  GLU B O    1 
ATOM   9913  C CB   . GLU B 1 317 ? -15.885 22.156  49.863 1.00 46.40 ?  283  GLU B CB   1 
ATOM   9914  C CG   . GLU B 1 317 ? -14.598 21.740  49.152 1.00 51.15 ?  283  GLU B CG   1 
ATOM   9915  C CD   . GLU B 1 317 ? -13.414 21.624  50.108 1.00 67.01 ?  283  GLU B CD   1 
ATOM   9916  O OE1  . GLU B 1 317 ? -13.531 22.095  51.260 1.00 70.82 ?  283  GLU B OE1  1 
ATOM   9917  O OE2  . GLU B 1 317 ? -12.363 21.075  49.706 1.00 67.41 ?  283  GLU B OE2  1 
ATOM   9918  H H    . GLU B 1 317 ? -16.286 24.472  49.106 1.00 40.84 ?  283  GLU B H    1 
ATOM   9919  H HA   . GLU B 1 317 ? -16.936 22.100  48.106 1.00 53.20 ?  283  GLU B HA   1 
ATOM   9920  H HB2  . GLU B 1 317 ? -15.666 22.876  50.474 1.00 55.67 ?  283  GLU B HB2  1 
ATOM   9921  H HB3  . GLU B 1 317 ? -16.210 21.388  50.358 1.00 55.67 ?  283  GLU B HB3  1 
ATOM   9922  H HG2  . GLU B 1 317 ? -14.732 20.876  48.733 1.00 61.38 ?  283  GLU B HG2  1 
ATOM   9923  H HG3  . GLU B 1 317 ? -14.378 22.405  48.481 1.00 61.38 ?  283  GLU B HG3  1 
ATOM   9924  N N    . ALA B 1 318 ? -18.918 23.406  50.200 1.00 33.59 ?  284  ALA B N    1 
ATOM   9925  C CA   . ALA B 1 318 ? -20.255 23.264  50.768 1.00 22.09 ?  284  ALA B CA   1 
ATOM   9926  C C    . ALA B 1 318 ? -21.359 23.558  49.755 1.00 32.65 ?  284  ALA B C    1 
ATOM   9927  O O    . ALA B 1 318 ? -22.524 23.224  50.000 1.00 44.55 ?  284  ALA B O    1 
ATOM   9928  C CB   . ALA B 1 318 ? -20.424 24.276  51.904 1.00 28.33 ?  284  ALA B CB   1 
ATOM   9929  H H    . ALA B 1 318 ? -18.557 24.176  50.325 1.00 40.31 ?  284  ALA B H    1 
ATOM   9930  H HA   . ALA B 1 318 ? -20.358 22.359  51.102 1.00 26.51 ?  284  ALA B HA   1 
ATOM   9931  H HB1  . ALA B 1 318 ? -21.340 24.246  52.221 1.00 34.00 ?  284  ALA B HB1  1 
ATOM   9932  H HB2  . ALA B 1 318 ? -19.816 24.046  52.625 1.00 34.00 ?  284  ALA B HB2  1 
ATOM   9933  H HB3  . ALA B 1 318 ? -20.219 25.164  51.569 1.00 34.00 ?  284  ALA B HB3  1 
ATOM   9934  N N    . ILE B 1 319 ? -21.009 24.181  48.639 1.00 23.86 ?  285  ILE B N    1 
ATOM   9935  C CA   . ILE B 1 319 ? -21.917 24.525  47.544 1.00 30.52 ?  285  ILE B CA   1 
ATOM   9936  C C    . ILE B 1 319 ? -21.872 23.491  46.429 1.00 30.56 ?  285  ILE B C    1 
ATOM   9937  O O    . ILE B 1 319 ? -22.867 23.304  45.710 1.00 28.27 ?  285  ILE B O    1 
ATOM   9938  C CB   . ILE B 1 319 ? -21.543 25.916  47.015 1.00 32.16 ?  285  ILE B CB   1 
ATOM   9939  C CG1  . ILE B 1 319 ? -22.190 26.970  47.913 1.00 39.97 ?  285  ILE B CG1  1 
ATOM   9940  C CG2  . ILE B 1 319 ? -21.914 26.053  45.522 1.00 48.75 ?  285  ILE B CG2  1 
ATOM   9941  C CD1  . ILE B 1 319 ? -22.083 28.389  47.406 1.00 50.50 ?  285  ILE B CD1  1 
ATOM   9942  H H    . ILE B 1 319 ? -20.202 24.432  48.477 1.00 28.63 ?  285  ILE B H    1 
ATOM   9943  H HA   . ILE B 1 319 ? -22.828 24.515  47.876 1.00 36.63 ?  285  ILE B HA   1 
ATOM   9944  H HB   . ILE B 1 319 ? -20.582 26.049  47.054 1.00 38.59 ?  285  ILE B HB   1 
ATOM   9945  H HG12 . ILE B 1 319 ? -23.133 26.762  48.000 1.00 47.97 ?  285  ILE B HG12 1 
ATOM   9946  H HG13 . ILE B 1 319 ? -21.761 26.938  48.783 1.00 47.97 ?  285  ILE B HG13 1 
ATOM   9947  H HG21 . ILE B 1 319 ? -21.750 26.967  45.238 1.00 58.50 ?  285  ILE B HG21 1 
ATOM   9948  H HG22 . ILE B 1 319 ? -21.366 25.443  45.003 1.00 58.50 ?  285  ILE B HG22 1 
ATOM   9949  H HG23 . ILE B 1 319 ? -22.852 25.835  45.408 1.00 58.50 ?  285  ILE B HG23 1 
ATOM   9950  H HD11 . ILE B 1 319 ? -22.505 28.985  48.045 1.00 60.60 ?  285  ILE B HD11 1 
ATOM   9951  H HD12 . ILE B 1 319 ? -21.146 28.620  47.308 1.00 60.60 ?  285  ILE B HD12 1 
ATOM   9952  H HD13 . ILE B 1 319 ? -22.531 28.453  46.548 1.00 60.60 ?  285  ILE B HD13 1 
ATOM   9953  N N    . ASP B 1 320 ? -20.726 22.861  46.222 1.00 27.05 ?  286  ASP B N    1 
ATOM   9954  C CA   . ASP B 1 320 ? -20.601 21.848  45.178 1.00 29.54 ?  286  ASP B CA   1 
ATOM   9955  C C    . ASP B 1 320 ? -21.701 20.813  45.339 1.00 30.17 ?  286  ASP B C    1 
ATOM   9956  O O    . ASP B 1 320 ? -21.928 20.310  46.434 1.00 31.67 ?  286  ASP B O    1 
ATOM   9957  C CB   . ASP B 1 320 ? -19.236 21.167  45.306 1.00 30.79 ?  286  ASP B CB   1 
ATOM   9958  H H    . ASP B 1 320 ? -20.005 22.999  46.670 1.00 32.46 ?  286  ASP B H    1 
ATOM   9959  H HA   . ASP B 1 320 ? -20.672 22.257  44.301 1.00 35.44 ?  286  ASP B HA   1 
ATOM   9960  N N    . ASN B 1 321 ? -22.392 20.483  44.233 1.00 29.73 ?  287  ASN B N    1 
ATOM   9961  C CA   . ASN B 1 321 ? -23.520 19.553  44.265 1.00 26.55 ?  287  ASN B CA   1 
ATOM   9962  C C    . ASN B 1 321 ? -23.423 18.471  43.187 1.00 26.94 ?  287  ASN B C    1 
ATOM   9963  O O    . ASN B 1 321 ? -24.442 17.834  42.861 1.00 27.62 ?  287  ASN B O    1 
ATOM   9964  C CB   . ASN B 1 321 ? -24.867 20.287  44.167 1.00 23.67 ?  287  ASN B CB   1 
ATOM   9965  C CG   . ASN B 1 321 ? -24.964 21.179  42.935 1.00 21.43 ?  287  ASN B CG   1 
ATOM   9966  O OD1  . ASN B 1 321 ? -24.211 21.010  41.971 1.00 25.09 ?  287  ASN B OD1  1 
ATOM   9967  N ND2  . ASN B 1 321 ? -25.929 22.100  42.947 1.00 25.75 ?  287  ASN B ND2  1 
ATOM   9968  H H    . ASN B 1 321 ? -22.220 20.790  43.449 1.00 35.68 ?  287  ASN B H    1 
ATOM   9969  H HA   . ASN B 1 321 ? -23.499 19.104  45.124 1.00 31.86 ?  287  ASN B HA   1 
ATOM   9970  H HB2  . ASN B 1 321 ? -25.581 19.632  44.121 1.00 28.41 ?  287  ASN B HB2  1 
ATOM   9971  H HB3  . ASN B 1 321 ? -24.979 20.846  44.951 1.00 28.41 ?  287  ASN B HB3  1 
ATOM   9972  H HD21 . ASN B 1 321 ? -26.027 22.629  42.276 1.00 30.90 ?  287  ASN B HD21 1 
ATOM   9973  H HD22 . ASN B 1 321 ? -26.452 22.165  43.626 1.00 30.90 ?  287  ASN B HD22 1 
ATOM   9974  N N    . ASN B 1 322 ? -22.235 18.249  42.639 1.00 27.70 ?  288  ASN B N    1 
ATOM   9975  C CA   . ASN B 1 322 ? -21.990 17.148  41.708 1.00 27.85 ?  288  ASN B CA   1 
ATOM   9976  C C    . ASN B 1 322 ? -22.809 17.320  40.430 1.00 32.76 ?  288  ASN B C    1 
ATOM   9977  O O    . ASN B 1 322 ? -23.317 16.343  39.858 1.00 28.08 ?  288  ASN B O    1 
ATOM   9978  C CB   . ASN B 1 322 ? -22.257 15.784  42.360 1.00 36.92 ?  288  ASN B CB   1 
ATOM   9979  H H    . ASN B 1 322 ? -21.538 18.730  42.792 1.00 33.24 ?  288  ASN B H    1 
ATOM   9980  H HA   . ASN B 1 322 ? -21.053 17.165  41.458 1.00 33.42 ?  288  ASN B HA   1 
ATOM   9981  N N    . THR B 1 323 ? -22.946 18.576  39.993 1.00 20.72 ?  289  THR B N    1 
ATOM   9982  C CA   . THR B 1 323 ? -23.593 18.897  38.722 1.00 18.56 ?  289  THR B CA   1 
ATOM   9983  C C    . THR B 1 323 ? -22.834 20.041  38.060 1.00 19.29 ?  289  THR B C    1 
ATOM   9984  O O    . THR B 1 323 ? -22.058 20.741  38.710 1.00 23.42 ?  289  THR B O    1 
ATOM   9985  C CB   . THR B 1 323 ? -25.062 19.318  38.889 1.00 17.52 ?  289  THR B CB   1 
ATOM   9986  O OG1  . THR B 1 323 ? -25.151 20.621  39.532 1.00 19.90 ?  289  THR B OG1  1 
ATOM   9987  C CG2  . THR B 1 323 ? -25.875 18.279  39.658 1.00 19.84 ?  289  THR B CG2  1 
ATOM   9988  H H    . THR B 1 323 ? -22.668 19.268  40.423 1.00 24.87 ?  289  THR B H    1 
ATOM   9989  H HA   . THR B 1 323 ? -23.563 18.107  38.159 1.00 22.27 ?  289  THR B HA   1 
ATOM   9990  H HB   . THR B 1 323 ? -25.460 19.384  38.006 1.00 21.02 ?  289  THR B HB   1 
ATOM   9991  H HG1  . THR B 1 323 ? -24.640 20.648  40.198 1.00 23.89 ?  289  THR B HG1  1 
ATOM   9992  H HG21 . THR B 1 323 ? -26.809 18.540  39.682 1.00 23.80 ?  289  THR B HG21 1 
ATOM   9993  H HG22 . THR B 1 323 ? -25.801 17.414  39.227 1.00 23.80 ?  289  THR B HG22 1 
ATOM   9994  H HG23 . THR B 1 323 ? -25.545 18.207  40.568 1.00 23.80 ?  289  THR B HG23 1 
ATOM   9995  N N    . GLY B 1 324 ? -23.082 20.254  36.761 1.00 17.65 ?  290  GLY B N    1 
ATOM   9996  C CA   . GLY B 1 324 ? -22.563 21.387  36.030 1.00 14.53 ?  290  GLY B CA   1 
ATOM   9997  C C    . GLY B 1 324 ? -21.428 21.113  35.062 1.00 17.34 ?  290  GLY B C    1 
ATOM   9998  O O    . GLY B 1 324 ? -20.971 22.050  34.391 1.00 18.50 ?  290  GLY B O    1 
ATOM   9999  H H    . GLY B 1 324 ? -23.566 19.732  36.277 1.00 21.19 ?  290  GLY B H    1 
ATOM   10000 H HA2  . GLY B 1 324 ? -23.290 21.776  35.519 1.00 17.43 ?  290  GLY B HA2  1 
ATOM   10001 H HA3  . GLY B 1 324 ? -22.243 22.040  36.671 1.00 17.43 ?  290  GLY B HA3  1 
ATOM   10002 N N    . ILE B 1 325 ? -20.932 19.886  35.006 1.00 15.25 ?  291  ILE B N    1 
ATOM   10003 C CA   . ILE B 1 325 ? -19.832 19.520  34.093 1.00 14.91 ?  291  ILE B CA   1 
ATOM   10004 C C    . ILE B 1 325 ? -20.361 19.058  32.740 1.00 13.47 ?  291  ILE B C    1 
ATOM   10005 O O    . ILE B 1 325 ? -19.980 19.597  31.696 1.00 13.39 ?  291  ILE B O    1 
ATOM   10006 C CB   . ILE B 1 325 ? -18.943 18.438  34.740 1.00 13.28 ?  291  ILE B CB   1 
ATOM   10007 C CG1  . ILE B 1 325 ? -18.316 18.955  36.028 1.00 16.76 ?  291  ILE B CG1  1 
ATOM   10008 C CG2  . ILE B 1 325 ? -17.859 18.023  33.749 1.00 14.69 ?  291  ILE B CG2  1 
ATOM   10009 C CD1  . ILE B 1 325 ? -17.502 20.195  35.862 1.00 23.73 ?  291  ILE B CD1  1 
ATOM   10010 H H    . ILE B 1 325 ? -21.211 19.231  35.488 1.00 18.30 ?  291  ILE B H    1 
ATOM   10011 H HA   . ILE B 1 325 ? -19.288 20.309  33.945 1.00 17.89 ?  291  ILE B HA   1 
ATOM   10012 H HB   . ILE B 1 325 ? -19.492 17.669  34.964 1.00 15.93 ?  291  ILE B HB   1 
ATOM   10013 H HG12 . ILE B 1 325 ? -19.025 19.152  36.660 1.00 20.11 ?  291  ILE B HG12 1 
ATOM   10014 H HG13 . ILE B 1 325 ? -17.733 18.267  36.387 1.00 20.11 ?  291  ILE B HG13 1 
ATOM   10015 H HG21 . ILE B 1 325 ? -17.212 17.462  34.205 1.00 17.63 ?  291  ILE B HG21 1 
ATOM   10016 H HG22 . ILE B 1 325 ? -18.269 17.531  33.020 1.00 17.63 ?  291  ILE B HG22 1 
ATOM   10017 H HG23 . ILE B 1 325 ? -17.423 18.819  33.407 1.00 17.63 ?  291  ILE B HG23 1 
ATOM   10018 H HD11 . ILE B 1 325 ? -17.023 20.371  36.687 1.00 28.47 ?  291  ILE B HD11 1 
ATOM   10019 H HD12 . ILE B 1 325 ? -16.872 20.064  35.136 1.00 28.47 ?  291  ILE B HD12 1 
ATOM   10020 H HD13 . ILE B 1 325 ? -18.093 20.936  35.657 1.00 28.47 ?  291  ILE B HD13 1 
ATOM   10021 N N    . ASP B 1 326 ? -21.276 18.098  32.756 1.00 13.41 ?  292  ASP B N    1 
ATOM   10022 C CA   . ASP B 1 326 ? -21.911 17.547  31.563 1.00 11.76 ?  292  ASP B CA   1 
ATOM   10023 C C    . ASP B 1 326 ? -23.426 17.695  31.637 1.00 13.54 ?  292  ASP B C    1 
ATOM   10024 O O    . ASP B 1 326 ? -24.142 17.106  30.827 1.00 14.32 ?  292  ASP B O    1 
ATOM   10025 C CB   . ASP B 1 326 ? -21.531 16.074  31.370 1.00 13.65 ?  292  ASP B CB   1 
ATOM   10026 C CG   . ASP B 1 326 ? -20.063 15.891  31.026 1.00 12.33 ?  292  ASP B CG   1 
ATOM   10027 O OD1  . ASP B 1 326 ? -19.668 16.410  29.959 1.00 13.51 ?  292  ASP B OD1  1 
ATOM   10028 O OD2  . ASP B 1 326 ? -19.367 15.211  31.799 1.00 12.64 ?  292  ASP B OD2  1 
ATOM   10029 H H    . ASP B 1 326 ? -21.561 17.730  33.480 1.00 16.09 ?  292  ASP B H    1 
ATOM   10030 H HA   . ASP B 1 326 ? -21.588 18.023  30.781 1.00 14.11 ?  292  ASP B HA   1 
ATOM   10031 H HB2  . ASP B 1 326 ? -21.710 15.591  32.192 1.00 16.38 ?  292  ASP B HB2  1 
ATOM   10032 H HB3  . ASP B 1 326 ? -22.059 15.703  30.645 1.00 16.38 ?  292  ASP B HB3  1 
ATOM   10033 N N    . ASP B 1 327 ? -23.925 18.477  32.600 1.00 13.20 ?  293  ASP B N    1 
ATOM   10034 C CA   . ASP B 1 327 ? -25.350 18.711  32.781 1.00 14.48 ?  293  ASP B CA   1 
ATOM   10035 C C    . ASP B 1 327 ? -25.499 20.134  33.336 1.00 14.08 ?  293  ASP B C    1 
ATOM   10036 O O    . ASP B 1 327 ? -24.521 20.832  33.622 1.00 14.70 ?  293  ASP B O    1 
ATOM   10037 C CB   . ASP B 1 327 ? -25.994 17.615  33.660 1.00 13.55 ?  293  ASP B CB   1 
ATOM   10038 C CG   . ASP B 1 327 ? -25.286 17.378  34.986 1.00 15.15 ?  293  ASP B CG   1 
ATOM   10039 O OD1  . ASP B 1 327 ? -24.606 18.308  35.449 1.00 15.01 ?  293  ASP B OD1  1 
ATOM   10040 O OD2  . ASP B 1 327 ? -25.454 16.272  35.566 1.00 16.63 ?  293  ASP B OD2  1 
ATOM   10041 H H    . ASP B 1 327 ? -23.440 18.894  33.175 1.00 15.85 ?  293  ASP B H    1 
ATOM   10042 H HA   . ASP B 1 327 ? -25.830 18.678  31.939 1.00 17.37 ?  293  ASP B HA   1 
ATOM   10043 H HB2  . ASP B 1 327 ? -26.908 17.873  33.857 1.00 16.26 ?  293  ASP B HB2  1 
ATOM   10044 H HB3  . ASP B 1 327 ? -25.984 16.778  33.168 1.00 16.26 ?  293  ASP B HB3  1 
ATOM   10045 N N    . GLN B 1 328 ? -26.757 20.578  33.452 1.00 14.93 ?  294  GLN B N    1 
ATOM   10046 C CA   . GLN B 1 328 ? -27.031 21.858  34.075 1.00 15.75 ?  294  GLN B CA   1 
ATOM   10047 C C    . GLN B 1 328 ? -26.536 21.846  35.516 1.00 13.77 ?  294  GLN B C    1 
ATOM   10048 O O    . GLN B 1 328 ? -26.652 20.862  36.232 1.00 15.84 ?  294  GLN B O    1 
ATOM   10049 C CB   . GLN B 1 328 ? -28.541 22.094  33.997 1.00 17.83 ?  294  GLN B CB   1 
ATOM   10050 C CG   . GLN B 1 328 ? -29.131 23.208  34.798 1.00 25.93 ?  294  GLN B CG   1 
ATOM   10051 C CD   . GLN B 1 328 ? -30.665 23.085  34.804 1.00 39.31 ?  294  GLN B CD   1 
ATOM   10052 O OE1  . GLN B 1 328 ? -31.242 22.387  33.945 1.00 25.66 ?  294  GLN B OE1  1 
ATOM   10053 N NE2  . GLN B 1 328 ? -31.320 23.748  35.761 1.00 39.42 ?  294  GLN B NE2  1 
ATOM   10054 H H    . GLN B 1 328 ? -27.455 20.156  33.179 1.00 17.92 ?  294  GLN B H    1 
ATOM   10055 H HA   . GLN B 1 328 ? -26.576 22.588  33.627 1.00 18.90 ?  294  GLN B HA   1 
ATOM   10056 H HB2  . GLN B 1 328 ? -28.762 22.274  33.070 1.00 21.40 ?  294  GLN B HB2  1 
ATOM   10057 H HB3  . GLN B 1 328 ? -28.981 21.280  34.291 1.00 21.40 ?  294  GLN B HB3  1 
ATOM   10058 H HG2  . GLN B 1 328 ? -28.809 23.161  35.712 1.00 31.11 ?  294  GLN B HG2  1 
ATOM   10059 H HG3  . GLN B 1 328 ? -28.886 24.060  34.404 1.00 31.11 ?  294  GLN B HG3  1 
ATOM   10060 H HE21 . GLN B 1 328 ? -30.884 24.215  36.337 1.00 47.30 ?  294  GLN B HE21 1 
ATOM   10061 H HE22 . GLN B 1 328 ? -32.179 23.708  35.802 1.00 47.30 ?  294  GLN B HE22 1 
ATOM   10062 N N    . ARG B 1 329 ? -25.989 22.969  35.933 1.00 17.24 ?  295  ARG B N    1 
ATOM   10063 C CA   . ARG B 1 329 ? -25.593 23.122  37.324 1.00 16.46 ?  295  ARG B CA   1 
ATOM   10064 C C    . ARG B 1 329 ? -26.853 23.412  38.121 1.00 15.59 ?  295  ARG B C    1 
ATOM   10065 O O    . ARG B 1 329 ? -27.527 24.416  37.881 1.00 18.07 ?  295  ARG B O    1 
ATOM   10066 C CB   . ARG B 1 329 ? -24.625 24.304  37.422 1.00 19.80 ?  295  ARG B CB   1 
ATOM   10067 C CG   . ARG B 1 329 ? -24.165 24.594  38.833 1.00 21.82 ?  295  ARG B CG   1 
ATOM   10068 C CD   . ARG B 1 329 ? -23.275 25.849  38.902 1.00 26.92 ?  295  ARG B CD   1 
ATOM   10069 N NE   . ARG B 1 329 ? -22.635 25.956  40.208 1.00 30.04 ?  295  ARG B NE   1 
ATOM   10070 C CZ   . ARG B 1 329 ? -21.732 26.873  40.531 1.00 36.32 ?  295  ARG B CZ   1 
ATOM   10071 N NH1  . ARG B 1 329 ? -21.323 27.776  39.658 1.00 27.07 ?  295  ARG B NH1  1 
ATOM   10072 N NH2  . ARG B 1 329 ? -21.215 26.867  41.756 1.00 26.40 ?  295  ARG B NH2  1 
ATOM   10073 H H    . ARG B 1 329 ? -25.837 23.655  35.437 1.00 20.68 ?  295  ARG B H    1 
ATOM   10074 H HA   . ARG B 1 329 ? -25.162 22.324  37.669 1.00 19.75 ?  295  ARG B HA   1 
ATOM   10075 H HB2  . ARG B 1 329 ? -23.840 24.109  36.887 1.00 23.76 ?  295  ARG B HB2  1 
ATOM   10076 H HB3  . ARG B 1 329 ? -25.067 25.098  37.084 1.00 23.76 ?  295  ARG B HB3  1 
ATOM   10077 H HG2  . ARG B 1 329 ? -24.939 24.740  39.398 1.00 26.18 ?  295  ARG B HG2  1 
ATOM   10078 H HG3  . ARG B 1 329 ? -23.651 23.840  39.163 1.00 26.18 ?  295  ARG B HG3  1 
ATOM   10079 H HD2  . ARG B 1 329 ? -22.584 25.794  38.223 1.00 32.30 ?  295  ARG B HD2  1 
ATOM   10080 H HD3  . ARG B 1 329 ? -23.818 26.639  38.759 1.00 32.30 ?  295  ARG B HD3  1 
ATOM   10081 H HE   . ARG B 1 329 ? -22.858 25.385  40.810 1.00 36.05 ?  295  ARG B HE   1 
ATOM   10082 H HH11 . ARG B 1 329 ? -21.642 27.778  38.860 1.00 32.48 ?  295  ARG B HH11 1 
ATOM   10083 H HH12 . ARG B 1 329 ? -20.737 28.362  39.889 1.00 32.48 ?  295  ARG B HH12 1 
ATOM   10084 H HH21 . ARG B 1 329 ? -21.466 26.274  42.326 1.00 31.68 ?  295  ARG B HH21 1 
ATOM   10085 H HH22 . ARG B 1 329 ? -20.629 27.456  41.979 1.00 31.68 ?  295  ARG B HH22 1 
ATOM   10086 N N    . GLU B 1 330 ? -27.174 22.546  39.073 1.00 17.10 ?  296  GLU B N    1 
ATOM   10087 C CA   . GLU B 1 330 ? -28.387 22.742  39.858 1.00 20.38 ?  296  GLU B CA   1 
ATOM   10088 C C    . GLU B 1 330 ? -28.218 23.884  40.860 1.00 19.26 ?  296  GLU B C    1 
ATOM   10089 O O    . GLU B 1 330 ? -27.130 24.116  41.382 1.00 20.10 ?  296  GLU B O    1 
ATOM   10090 C CB   . GLU B 1 330 ? -28.753 21.458  40.587 1.00 21.10 ?  296  GLU B CB   1 
ATOM   10091 C CG   . GLU B 1 330 ? -29.041 20.313  39.628 1.00 24.57 ?  296  GLU B CG   1 
ATOM   10092 C CD   . GLU B 1 330 ? -30.370 20.464  38.932 1.00 36.34 ?  296  GLU B CD   1 
ATOM   10093 O OE1  . GLU B 1 330 ? -31.316 21.005  39.555 1.00 33.19 ?  296  GLU B OE1  1 
ATOM   10094 O OE2  . GLU B 1 330 ? -30.465 20.064  37.750 1.00 28.66 ?  296  GLU B OE2  1 
ATOM   10095 H H    . GLU B 1 330 ? -26.715 21.849  39.281 1.00 20.52 ?  296  GLU B H    1 
ATOM   10096 H HA   . GLU B 1 330 ? -29.117 22.977  39.265 1.00 24.45 ?  296  GLU B HA   1 
ATOM   10097 H HB2  . GLU B 1 330 ? -28.014 21.196  41.158 1.00 25.32 ?  296  GLU B HB2  1 
ATOM   10098 H HB3  . GLU B 1 330 ? -29.547 21.612  41.122 1.00 25.32 ?  296  GLU B HB3  1 
ATOM   10099 H HG2  . GLU B 1 330 ? -28.348 20.284  38.951 1.00 29.48 ?  296  GLU B HG2  1 
ATOM   10100 H HG3  . GLU B 1 330 ? -29.055 19.479  40.125 1.00 29.48 ?  296  GLU B HG3  1 
ATOM   10101 N N    . ASP B 1 331 ? -29.309 24.614  41.083 1.00 19.20 ?  297  ASP B N    1 
ATOM   10102 C CA   . ASP B 1 331 ? -29.341 25.688  42.072 1.00 20.26 ?  297  ASP B CA   1 
ATOM   10103 C C    . ASP B 1 331 ? -28.898 25.157  43.430 1.00 19.87 ?  297  ASP B C    1 
ATOM   10104 O O    . ASP B 1 331 ? -29.324 24.079  43.870 1.00 21.44 ?  297  ASP B O    1 
ATOM   10105 C CB   . ASP B 1 331 ? -30.801 26.175  42.239 1.00 21.73 ?  297  ASP B CB   1 
ATOM   10106 C CG   . ASP B 1 331 ? -31.267 27.150  41.183 1.00 31.67 ?  297  ASP B CG   1 
ATOM   10107 O OD1  . ASP B 1 331 ? -30.637 27.292  40.118 1.00 26.69 ?  297  ASP B OD1  1 
ATOM   10108 O OD2  . ASP B 1 331 ? -32.361 27.731  41.410 1.00 20.76 ?  297  ASP B OD2  1 
ATOM   10109 H H    . ASP B 1 331 ? -30.055 24.507  40.669 1.00 23.03 ?  297  ASP B H    1 
ATOM   10110 H HA   . ASP B 1 331 ? -28.763 26.411  41.782 1.00 24.32 ?  297  ASP B HA   1 
ATOM   10111 H HB2  . ASP B 1 331 ? -31.389 25.404  42.203 1.00 26.07 ?  297  ASP B HB2  1 
ATOM   10112 H HB3  . ASP B 1 331 ? -30.883 26.616  43.099 1.00 26.07 ?  297  ASP B HB3  1 
ATOM   10113 N N    . VAL B 1 332 ? -28.046 25.919  44.104 1.00 25.07 ?  298  VAL B N    1 
ATOM   10114 C CA   . VAL B 1 332 ? -27.817 25.711  45.528 1.00 26.73 ?  298  VAL B CA   1 
ATOM   10115 C C    . VAL B 1 332 ? -28.798 26.604  46.265 1.00 20.04 ?  298  VAL B C    1 
ATOM   10116 O O    . VAL B 1 332 ? -28.953 27.780  45.934 1.00 24.18 ?  298  VAL B O    1 
ATOM   10117 C CB   . VAL B 1 332 ? -26.367 26.049  45.920 1.00 29.99 ?  298  VAL B CB   1 
ATOM   10118 H H    . VAL B 1 332 ? -27.590 26.562  43.760 1.00 30.09 ?  298  VAL B H    1 
ATOM   10119 H HA   . VAL B 1 332 ? -27.974 24.782  45.759 1.00 32.08 ?  298  VAL B HA   1 
ATOM   10120 N N    . ASP B 1 333 ? -29.519 26.025  47.220 1.00 19.36 ?  299  ASP B N    1 
ATOM   10121 C CA   . ASP B 1 333 ? -30.480 26.772  48.004 1.00 19.27 ?  299  ASP B CA   1 
ATOM   10122 C C    . ASP B 1 333 ? -29.705 27.662  48.959 1.00 22.67 ?  299  ASP B C    1 
ATOM   10123 O O    . ASP B 1 333 ? -29.180 27.178  49.953 1.00 22.18 ?  299  ASP B O    1 
ATOM   10124 C CB   . ASP B 1 333 ? -31.344 25.801  48.793 1.00 19.03 ?  299  ASP B CB   1 
ATOM   10125 C CG   . ASP B 1 333 ? -32.373 26.490  49.650 1.00 26.06 ?  299  ASP B CG   1 
ATOM   10126 O OD1  . ASP B 1 333 ? -32.465 27.750  49.650 1.00 24.19 ?  299  ASP B OD1  1 
ATOM   10127 O OD2  . ASP B 1 333 ? -33.123 25.750  50.319 1.00 30.41 ?  299  ASP B OD2  1 
ATOM   10128 H H    . ASP B 1 333 ? -29.466 25.193  47.430 1.00 23.23 ?  299  ASP B H    1 
ATOM   10129 H HA   . ASP B 1 333 ? -31.041 27.315  47.428 1.00 23.12 ?  299  ASP B HA   1 
ATOM   10130 H HB2  . ASP B 1 333 ? -31.813 25.220  48.172 1.00 22.83 ?  299  ASP B HB2  1 
ATOM   10131 H HB3  . ASP B 1 333 ? -30.775 25.273  49.375 1.00 22.83 ?  299  ASP B HB3  1 
ATOM   10132 N N    . LEU B 1 334 ? -29.653 28.953  48.666 1.00 17.77 ?  300  LEU B N    1 
ATOM   10133 C CA   . LEU B 1 334 ? -28.856 29.865  49.492 1.00 17.95 ?  300  LEU B CA   1 
ATOM   10134 C C    . LEU B 1 334 ? -29.494 30.118  50.853 1.00 21.36 ?  300  LEU B C    1 
ATOM   10135 O O    . LEU B 1 334 ? -28.848 30.755  51.706 1.00 23.24 ?  300  LEU B O    1 
ATOM   10136 C CB   . LEU B 1 334 ? -28.593 31.158  48.720 1.00 21.16 ?  300  LEU B CB   1 
ATOM   10137 C CG   . LEU B 1 334 ? -27.804 30.961  47.428 1.00 22.12 ?  300  LEU B CG   1 
ATOM   10138 C CD1  . LEU B 1 334 ? -27.684 32.281  46.672 1.00 26.69 ?  300  LEU B CD1  1 
ATOM   10139 C CD2  . LEU B 1 334 ? -26.405 30.409  47.707 1.00 26.21 ?  300  LEU B CD2  1 
ATOM   10140 H H    . LEU B 1 334 ? -30.060 29.325  48.007 1.00 21.32 ?  300  LEU B H    1 
ATOM   10141 H HA   . LEU B 1 334 ? -27.985 29.478  49.673 1.00 21.54 ?  300  LEU B HA   1 
ATOM   10142 H HB2  . LEU B 1 334 ? -29.445 31.560  48.488 1.00 25.40 ?  300  LEU B HB2  1 
ATOM   10143 H HB3  . LEU B 1 334 ? -28.086 31.760  49.287 1.00 25.40 ?  300  LEU B HB3  1 
ATOM   10144 H HG   . LEU B 1 334 ? -28.281 30.318  46.880 1.00 26.54 ?  300  LEU B HG   1 
ATOM   10145 H HD11 . LEU B 1 334 ? -27.232 32.122  45.828 1.00 32.03 ?  300  LEU B HD11 1 
ATOM   10146 H HD12 . LEU B 1 334 ? -28.573 32.634  46.509 1.00 32.03 ?  300  LEU B HD12 1 
ATOM   10147 H HD13 . LEU B 1 334 ? -27.173 32.907  47.208 1.00 32.03 ?  300  LEU B HD13 1 
ATOM   10148 H HD21 . LEU B 1 334 ? -25.889 30.429  46.886 1.00 31.46 ?  300  LEU B HD21 1 
ATOM   10149 H HD22 . LEU B 1 334 ? -25.977 30.960  48.380 1.00 31.46 ?  300  LEU B HD22 1 
ATOM   10150 H HD23 . LEU B 1 334 ? -26.484 29.497  48.027 1.00 31.46 ?  300  LEU B HD23 1 
ATOM   10151 N N    . ASN B 1 335 ? -30.719 29.651  51.080 1.00 20.89 ?  301  ASN B N    1 
ATOM   10152 C CA   . ASN B 1 335 ? -31.393 29.770  52.381 1.00 23.03 ?  301  ASN B CA   1 
ATOM   10153 C C    . ASN B 1 335 ? -31.350 28.476  53.185 1.00 17.56 ?  301  ASN B C    1 
ATOM   10154 O O    . ASN B 1 335 ? -31.923 28.439  54.265 1.00 23.53 ?  301  ASN B O    1 
ATOM   10155 C CB   . ASN B 1 335 ? -32.878 30.213  52.221 1.00 20.34 ?  301  ASN B CB   1 
ATOM   10156 C CG   . ASN B 1 335 ? -33.023 31.692  51.845 1.00 39.20 ?  301  ASN B CG   1 
ATOM   10157 O OD1  . ASN B 1 335 ? -33.525 32.032  50.755 1.00 38.27 ?  301  ASN B OD1  1 
ATOM   10158 N ND2  . ASN B 1 335 ? -32.562 32.576  52.725 1.00 30.25 ?  301  ASN B ND2  1 
ATOM   10159 H H    . ASN B 1 335 ? -31.195 29.251  50.486 1.00 25.07 ?  301  ASN B H    1 
ATOM   10160 H HA   . ASN B 1 335 ? -30.938 30.467  52.879 1.00 27.64 ?  301  ASN B HA   1 
ATOM   10161 H HB2  . ASN B 1 335 ? -33.291 29.684  51.520 1.00 24.41 ?  301  ASN B HB2  1 
ATOM   10162 H HB3  . ASN B 1 335 ? -33.342 30.071  53.061 1.00 24.41 ?  301  ASN B HB3  1 
ATOM   10163 H HD21 . ASN B 1 335 ? -32.205 32.306  53.460 1.00 36.30 ?  301  ASN B HD21 1 
ATOM   10164 H HD22 . ASN B 1 335 ? -32.620 33.418  52.560 1.00 36.30 ?  301  ASN B HD22 1 
ATOM   10165 N N    . ASP B 1 336 ? -30.700 27.443  52.658 1.00 16.70 ?  302  ASP B N    1 
ATOM   10166 C CA   . ASP B 1 336 ? -30.644 26.112  53.244 1.00 23.54 ?  302  ASP B CA   1 
ATOM   10167 C C    . ASP B 1 336 ? -30.078 26.145  54.662 1.00 21.16 ?  302  ASP B C    1 
ATOM   10168 O O    . ASP B 1 336 ? -29.155 26.916  54.975 1.00 19.27 ?  302  ASP B O    1 
ATOM   10169 C CB   . ASP B 1 336 ? -29.676 25.312  52.347 1.00 28.11 ?  302  ASP B CB   1 
ATOM   10170 C CG   . ASP B 1 336 ? -29.553 23.889  52.712 1.00 35.78 ?  302  ASP B CG   1 
ATOM   10171 O OD1  . ASP B 1 336 ? -30.514 23.129  52.526 1.00 35.35 ?  302  ASP B OD1  1 
ATOM   10172 O OD2  . ASP B 1 336 ? -28.448 23.519  53.180 1.00 36.71 ?  302  ASP B OD2  1 
ATOM   10173 H H    . ASP B 1 336 ? -30.259 27.490  51.921 1.00 20.04 ?  302  ASP B H    1 
ATOM   10174 H HA   . ASP B 1 336 ? -31.526 25.712  53.298 1.00 28.25 ?  302  ASP B HA   1 
ATOM   10175 H HB2  . ASP B 1 336 ? -29.993 25.354  51.432 1.00 33.73 ?  302  ASP B HB2  1 
ATOM   10176 H HB3  . ASP B 1 336 ? -28.793 25.709  52.411 1.00 33.73 ?  302  ASP B HB3  1 
ATOM   10177 N N    . GLU B 1 337 ? -30.581 25.256  55.515 1.00 21.91 ?  303  GLU B N    1 
ATOM   10178 C CA   . GLU B 1 337 ? -30.056 25.165  56.876 1.00 24.57 ?  303  GLU B CA   1 
ATOM   10179 C C    . GLU B 1 337 ? -28.585 24.754  56.875 1.00 18.24 ?  303  GLU B C    1 
ATOM   10180 O O    . GLU B 1 337 ? -27.763 25.323  57.629 1.00 19.31 ?  303  GLU B O    1 
ATOM   10181 C CB   . GLU B 1 337 ? -30.883 24.142  57.663 1.00 26.75 ?  303  GLU B CB   1 
ATOM   10182 C CG   . GLU B 1 337 ? -31.322 24.596  59.046 1.00 48.54 ?  303  GLU B CG   1 
ATOM   10183 C CD   . GLU B 1 337 ? -31.787 23.429  59.925 1.00 66.25 ?  303  GLU B CD   1 
ATOM   10184 O OE1  . GLU B 1 337 ? -33.013 23.290  60.153 1.00 62.94 ?  303  GLU B OE1  1 
ATOM   10185 O OE2  . GLU B 1 337 ? -30.927 22.640  60.382 1.00 57.88 ?  303  GLU B OE2  1 
ATOM   10186 H H    . GLU B 1 337 ? -31.215 24.703  55.336 1.00 26.29 ?  303  GLU B H    1 
ATOM   10187 H HA   . GLU B 1 337 ? -30.127 26.032  57.306 1.00 29.49 ?  303  GLU B HA   1 
ATOM   10188 H HB2  . GLU B 1 337 ? -31.684 23.940  57.155 1.00 32.10 ?  303  GLU B HB2  1 
ATOM   10189 H HB3  . GLU B 1 337 ? -30.350 23.339  57.776 1.00 32.10 ?  303  GLU B HB3  1 
ATOM   10190 H HG2  . GLU B 1 337 ? -30.575 25.028  59.490 1.00 58.25 ?  303  GLU B HG2  1 
ATOM   10191 H HG3  . GLU B 1 337 ? -32.060 25.219  58.956 1.00 58.25 ?  303  GLU B HG3  1 
ATOM   10192 N N    . GLU B 1 338 ? -28.210 23.783  56.055 1.00 20.24 ?  304  GLU B N    1 
ATOM   10193 C CA   . GLU B 1 338 ? -26.821 23.326  56.082 1.00 21.73 ?  304  GLU B CA   1 
ATOM   10194 C C    . GLU B 1 338 ? -25.873 24.394  55.548 1.00 21.66 ?  304  GLU B C    1 
ATOM   10195 O O    . GLU B 1 338 ? -24.793 24.632  56.115 1.00 21.09 ?  304  GLU B O    1 
ATOM   10196 C CB   . GLU B 1 338 ? -26.650 22.022  55.306 1.00 32.83 ?  304  GLU B CB   1 
ATOM   10197 C CG   . GLU B 1 338 ? -27.076 20.781  56.075 1.00 44.43 ?  304  GLU B CG   1 
ATOM   10198 C CD   . GLU B 1 338 ? -26.372 20.645  57.412 1.00 47.54 ?  304  GLU B CD   1 
ATOM   10199 O OE1  . GLU B 1 338 ? -27.077 20.535  58.438 1.00 48.56 ?  304  GLU B OE1  1 
ATOM   10200 O OE2  . GLU B 1 338 ? -25.115 20.663  57.437 1.00 48.06 ?  304  GLU B OE2  1 
ATOM   10201 H H    . GLU B 1 338 ? -28.720 23.382  55.490 1.00 24.29 ?  304  GLU B H    1 
ATOM   10202 H HA   . GLU B 1 338 ? -26.588 23.144  57.005 1.00 26.07 ?  304  GLU B HA   1 
ATOM   10203 H HB2  . GLU B 1 338 ? -27.186 22.068  54.499 1.00 39.40 ?  304  GLU B HB2  1 
ATOM   10204 H HB3  . GLU B 1 338 ? -25.713 21.919  55.076 1.00 39.40 ?  304  GLU B HB3  1 
ATOM   10205 H HG2  . GLU B 1 338 ? -28.031 20.825  56.242 1.00 53.31 ?  304  GLU B HG2  1 
ATOM   10206 H HG3  . GLU B 1 338 ? -26.869 19.995  55.546 1.00 53.31 ?  304  GLU B HG3  1 
ATOM   10207 N N    . LEU B 1 339 ? -26.232 25.065  54.470 1.00 20.29 ?  305  LEU B N    1 
ATOM   10208 C CA   . LEU B 1 339 ? -25.335 26.109  53.998 1.00 20.72 ?  305  LEU B CA   1 
ATOM   10209 C C    . LEU B 1 339 ? -25.225 27.215  55.028 1.00 16.81 ?  305  LEU B C    1 
ATOM   10210 O O    . LEU B 1 339 ? -24.134 27.754  55.245 1.00 17.21 ?  305  LEU B O    1 
ATOM   10211 C CB   . LEU B 1 339 ? -25.785 26.668  52.645 1.00 20.24 ?  305  LEU B CB   1 
ATOM   10212 C CG   . LEU B 1 339 ? -24.880 27.706  51.971 1.00 21.43 ?  305  LEU B CG   1 
ATOM   10213 C CD1  . LEU B 1 339 ? -23.489 27.155  51.670 1.00 22.20 ?  305  LEU B CD1  1 
ATOM   10214 C CD2  . LEU B 1 339 ? -25.556 28.177  50.684 1.00 23.15 ?  305  LEU B CD2  1 
ATOM   10215 H H    . LEU B 1 339 ? -26.952 24.945  54.014 1.00 24.35 ?  305  LEU B H    1 
ATOM   10216 H HA   . LEU B 1 339 ? -24.458 25.719  53.858 1.00 24.87 ?  305  LEU B HA   1 
ATOM   10217 H HB2  . LEU B 1 339 ? -25.866 25.924  52.028 1.00 24.28 ?  305  LEU B HB2  1 
ATOM   10218 H HB3  . LEU B 1 339 ? -26.650 27.090  52.771 1.00 24.28 ?  305  LEU B HB3  1 
ATOM   10219 H HG   . LEU B 1 339 ? -24.750 28.453  52.576 1.00 25.72 ?  305  LEU B HG   1 
ATOM   10220 H HD11 . LEU B 1 339 ? -23.002 27.802  51.136 1.00 26.63 ?  305  LEU B HD11 1 
ATOM   10221 H HD12 . LEU B 1 339 ? -23.023 26.998  52.506 1.00 26.63 ?  305  LEU B HD12 1 
ATOM   10222 H HD13 . LEU B 1 339 ? -23.579 26.322  51.180 1.00 26.63 ?  305  LEU B HD13 1 
ATOM   10223 H HD21 . LEU B 1 339 ? -24.987 28.832  50.250 1.00 27.78 ?  305  LEU B HD21 1 
ATOM   10224 H HD22 . LEU B 1 339 ? -25.689 27.415  50.100 1.00 27.78 ?  305  LEU B HD22 1 
ATOM   10225 H HD23 . LEU B 1 339 ? -26.411 28.578  50.905 1.00 27.78 ?  305  LEU B HD23 1 
ATOM   10226 N N    . ASN B 1 340 ? -26.317 27.563  55.692 1.00 15.44 ?  306  ASN B N    1 
ATOM   10227 C CA   . ASN B 1 340 ? -26.247 28.629  56.681 1.00 16.54 ?  306  ASN B CA   1 
ATOM   10228 C C    . ASN B 1 340 ? -25.381 28.244  57.877 1.00 17.24 ?  306  ASN B C    1 
ATOM   10229 O O    . ASN B 1 340 ? -24.740 29.123  58.473 1.00 17.03 ?  306  ASN B O    1 
ATOM   10230 C CB   . ASN B 1 340 ? -27.634 29.060  57.150 1.00 18.58 ?  306  ASN B CB   1 
ATOM   10231 C CG   . ASN B 1 340 ? -28.227 30.160  56.334 1.00 22.45 ?  306  ASN B CG   1 
ATOM   10232 O OD1  . ASN B 1 340 ? -27.678 31.276  56.200 1.00 21.83 ?  306  ASN B OD1  1 
ATOM   10233 N ND2  . ASN B 1 340 ? -29.412 29.885  55.790 1.00 28.73 ?  306  ASN B ND2  1 
ATOM   10234 H H    . ASN B 1 340 ? -27.093 27.207  55.593 1.00 18.53 ?  306  ASN B H    1 
ATOM   10235 H HA   . ASN B 1 340 ? -25.844 29.398  56.247 1.00 19.84 ?  306  ASN B HA   1 
ATOM   10236 H HB2  . ASN B 1 340 ? -28.232 28.298  57.098 1.00 22.29 ?  306  ASN B HB2  1 
ATOM   10237 H HB3  . ASN B 1 340 ? -27.572 29.371  58.066 1.00 22.29 ?  306  ASN B HB3  1 
ATOM   10238 H HD21 . ASN B 1 340 ? -29.811 30.474  55.307 1.00 34.48 ?  306  ASN B HD21 1 
ATOM   10239 H HD22 . ASN B 1 340 ? -29.778 29.118  55.921 1.00 34.48 ?  306  ASN B HD22 1 
ATOM   10240 N N    . LYS B 1 341 ? -25.376 26.982  58.272 1.00 15.81 ?  307  LYS B N    1 
ATOM   10241 C CA   . LYS B 1 341 ? -24.446 26.521  59.320 1.00 17.03 ?  307  LYS B CA   1 
ATOM   10242 C C    . LYS B 1 341 ? -23.007 26.684  58.877 1.00 17.34 ?  307  LYS B C    1 
ATOM   10243 O O    . LYS B 1 341 ? -22.136 27.027  59.694 1.00 16.69 ?  307  LYS B O    1 
ATOM   10244 C CB   . LYS B 1 341 ? -24.730 25.060  59.689 1.00 22.18 ?  307  LYS B CB   1 
ATOM   10245 H H    . LYS B 1 341 ? -25.891 26.368  57.960 1.00 18.97 ?  307  LYS B H    1 
ATOM   10246 H HA   . LYS B 1 341 ? -24.586 27.058  60.116 1.00 20.44 ?  307  LYS B HA   1 
ATOM   10247 N N    . ARG B 1 342 ? -22.703 26.410  57.613 1.00 16.05 ?  308  ARG B N    1 
ATOM   10248 C CA   . ARG B 1 342 ? -21.347 26.607  57.109 1.00 16.51 ?  308  ARG B CA   1 
ATOM   10249 C C    . ARG B 1 342 ? -20.972 28.094  57.068 1.00 16.81 ?  308  ARG B C    1 
ATOM   10250 O O    . ARG B 1 342 ? -19.850 28.472  57.458 1.00 16.16 ?  308  ARG B O    1 
ATOM   10251 C CB   . ARG B 1 342 ? -21.188 25.943  55.740 1.00 17.58 ?  308  ARG B CB   1 
ATOM   10252 C CG   . ARG B 1 342 ? -19.871 26.195  55.017 1.00 21.69 ?  308  ARG B CG   1 
ATOM   10253 C CD   . ARG B 1 342 ? -18.692 25.452  55.588 1.00 29.42 ?  308  ARG B CD   1 
ATOM   10254 N NE   . ARG B 1 342 ? -17.563 25.645  54.681 1.00 30.89 ?  308  ARG B NE   1 
ATOM   10255 C CZ   . ARG B 1 342 ? -16.318 25.289  54.937 1.00 31.66 ?  308  ARG B CZ   1 
ATOM   10256 N NH1  . ARG B 1 342 ? -16.002 24.635  56.042 1.00 24.61 ?  308  ARG B NH1  1 
ATOM   10257 N NH2  . ARG B 1 342 ? -15.365 25.600  54.063 1.00 35.33 ?  308  ARG B NH2  1 
ATOM   10258 H H    . ARG B 1 342 ? -23.258 26.110  57.029 1.00 19.26 ?  308  ARG B H    1 
ATOM   10259 H HA   . ARG B 1 342 ? -20.723 26.173  57.711 1.00 19.81 ?  308  ARG B HA   1 
ATOM   10260 H HB2  . ARG B 1 342 ? -21.270 24.984  55.858 1.00 21.10 ?  308  ARG B HB2  1 
ATOM   10261 H HB3  . ARG B 1 342 ? -21.897 26.268  55.163 1.00 21.10 ?  308  ARG B HB3  1 
ATOM   10262 H HG2  . ARG B 1 342 ? -19.968 25.921  54.092 1.00 26.03 ?  308  ARG B HG2  1 
ATOM   10263 H HG3  . ARG B 1 342 ? -19.668 27.142  55.063 1.00 26.03 ?  308  ARG B HG3  1 
ATOM   10264 H HD2  . ARG B 1 342 ? -18.464 25.804  56.462 1.00 35.30 ?  308  ARG B HD2  1 
ATOM   10265 H HD3  . ARG B 1 342 ? -18.892 24.505  55.653 1.00 35.30 ?  308  ARG B HD3  1 
ATOM   10266 H HE   . ARG B 1 342 ? -17.722 26.020  53.924 1.00 37.07 ?  308  ARG B HE   1 
ATOM   10267 H HH11 . ARG B 1 342 ? -16.614 24.433  56.612 1.00 29.53 ?  308  ARG B HH11 1 
ATOM   10268 H HH12 . ARG B 1 342 ? -15.185 24.411  56.190 1.00 29.53 ?  308  ARG B HH12 1 
ATOM   10269 H HH21 . ARG B 1 342 ? -15.563 26.028  53.344 1.00 42.39 ?  308  ARG B HH21 1 
ATOM   10270 H HH22 . ARG B 1 342 ? -14.549 25.374  54.218 1.00 42.39 ?  308  ARG B HH22 1 
ATOM   10271 N N    . VAL B 1 343 ? -21.871 28.964  56.612 1.00 14.28 ?  309  VAL B N    1 
ATOM   10272 C CA   . VAL B 1 343 ? -21.632 30.399  56.682 1.00 13.98 ?  309  VAL B CA   1 
ATOM   10273 C C    . VAL B 1 343 ? -21.364 30.826  58.125 1.00 14.27 ?  309  VAL B C    1 
ATOM   10274 O O    . VAL B 1 343 ? -20.441 31.602  58.386 1.00 14.44 ?  309  VAL B O    1 
ATOM   10275 C CB   . VAL B 1 343 ? -22.821 31.171  56.066 1.00 14.01 ?  309  VAL B CB   1 
ATOM   10276 C CG1  . VAL B 1 343 ? -22.727 32.628  56.339 1.00 15.19 ?  309  VAL B CG1  1 
ATOM   10277 C CG2  . VAL B 1 343 ? -22.881 30.890  54.547 1.00 16.51 ?  309  VAL B CG2  1 
ATOM   10278 H H    . VAL B 1 343 ? -22.625 28.749  56.259 1.00 17.13 ?  309  VAL B H    1 
ATOM   10279 H HA   . VAL B 1 343 ? -20.840 30.607  56.163 1.00 16.77 ?  309  VAL B HA   1 
ATOM   10280 H HB   . VAL B 1 343 ? -23.644 30.865  56.477 1.00 16.82 ?  309  VAL B HB   1 
ATOM   10281 H HG11 . VAL B 1 343 ? -23.315 33.101  55.729 1.00 18.22 ?  309  VAL B HG11 1 
ATOM   10282 H HG12 . VAL B 1 343 ? -22.997 32.796  57.255 1.00 18.22 ?  309  VAL B HG12 1 
ATOM   10283 H HG13 . VAL B 1 343 ? -21.811 32.916  56.205 1.00 18.22 ?  309  VAL B HG13 1 
ATOM   10284 H HG21 . VAL B 1 343 ? -23.671 31.316  54.179 1.00 19.81 ?  309  VAL B HG21 1 
ATOM   10285 H HG22 . VAL B 1 343 ? -22.084 31.250  54.128 1.00 19.81 ?  309  VAL B HG22 1 
ATOM   10286 H HG23 . VAL B 1 343 ? -22.926 29.931  54.405 1.00 19.81 ?  309  VAL B HG23 1 
ATOM   10287 N N    . ASP B 1 344 ? -22.178 30.334  59.080 1.00 14.06 ?  310  ASP B N    1 
ATOM   10288 C CA   . ASP B 1 344 ? -21.973 30.688  60.491 1.00 13.83 ?  310  ASP B CA   1 
ATOM   10289 C C    . ASP B 1 344 ? -20.562 30.300  60.935 1.00 13.44 ?  310  ASP B C    1 
ATOM   10290 O O    . ASP B 1 344 ? -19.902 31.075  61.641 1.00 13.97 ?  310  ASP B O    1 
ATOM   10291 C CB   . ASP B 1 344 ? -23.006 29.936  61.361 1.00 13.23 ?  310  ASP B CB   1 
ATOM   10292 C CG   . ASP B 1 344 ? -24.414 30.476  61.275 1.00 15.03 ?  310  ASP B CG   1 
ATOM   10293 O OD1  . ASP B 1 344 ? -24.630 31.568  60.752 1.00 15.75 ?  310  ASP B OD1  1 
ATOM   10294 O OD2  . ASP B 1 344 ? -25.276 29.745  61.823 1.00 16.69 ?  310  ASP B OD2  1 
ATOM   10295 H H    . ASP B 1 344 ? -22.841 29.805  58.937 1.00 16.87 ?  310  ASP B H    1 
ATOM   10296 H HA   . ASP B 1 344 ? -22.094 31.644  60.606 1.00 16.59 ?  310  ASP B HA   1 
ATOM   10297 H HB2  . ASP B 1 344 ? -23.031 29.009  61.078 1.00 15.87 ?  310  ASP B HB2  1 
ATOM   10298 H HB3  . ASP B 1 344 ? -22.728 29.993  62.289 1.00 15.87 ?  310  ASP B HB3  1 
ATOM   10299 N N    . TYR B 1 345 ? -20.113 29.102  60.568 1.00 12.59 ?  311  TYR B N    1 
ATOM   10300 C CA   . TYR B 1 345 ? -18.798 28.614  60.976 1.00 12.87 ?  311  TYR B CA   1 
ATOM   10301 C C    . TYR B 1 345 ? -17.712 29.530  60.432 1.00 14.16 ?  311  TYR B C    1 
ATOM   10302 O O    . TYR B 1 345 ? -16.811 29.979  61.160 1.00 13.44 ?  311  TYR B O    1 
ATOM   10303 C CB   . TYR B 1 345 ? -18.587 27.176  60.495 1.00 13.84 ?  311  TYR B CB   1 
ATOM   10304 C CG   . TYR B 1 345 ? -17.196 26.645  60.736 1.00 14.03 ?  311  TYR B CG   1 
ATOM   10305 C CD1  . TYR B 1 345 ? -16.739 26.488  62.027 1.00 15.16 ?  311  TYR B CD1  1 
ATOM   10306 C CD2  . TYR B 1 345 ? -16.382 26.283  59.689 1.00 15.55 ?  311  TYR B CD2  1 
ATOM   10307 C CE1  . TYR B 1 345 ? -15.464 26.018  62.270 1.00 15.88 ?  311  TYR B CE1  1 
ATOM   10308 C CE2  . TYR B 1 345 ? -15.080 25.799  59.937 1.00 17.87 ?  311  TYR B CE2  1 
ATOM   10309 C CZ   . TYR B 1 345 ? -14.668 25.680  61.241 1.00 16.89 ?  311  TYR B CZ   1 
ATOM   10310 O OH   . TYR B 1 345 ? -13.391 25.195  61.544 1.00 21.23 ?  311  TYR B OH   1 
ATOM   10311 H H    . TYR B 1 345 ? -20.552 28.547  60.080 1.00 15.11 ?  311  TYR B H    1 
ATOM   10312 H HA   . TYR B 1 345 ? -18.746 28.605  61.945 1.00 15.45 ?  311  TYR B HA   1 
ATOM   10313 H HB2  . TYR B 1 345 ? -19.208 26.598  60.964 1.00 16.61 ?  311  TYR B HB2  1 
ATOM   10314 H HB3  . TYR B 1 345 ? -18.755 27.140  59.541 1.00 16.61 ?  311  TYR B HB3  1 
ATOM   10315 H HD1  . TYR B 1 345 ? -17.295 26.701  62.742 1.00 18.19 ?  311  TYR B HD1  1 
ATOM   10316 H HD2  . TYR B 1 345 ? -16.691 26.357  58.815 1.00 18.65 ?  311  TYR B HD2  1 
ATOM   10317 H HE1  . TYR B 1 345 ? -15.156 25.936  63.144 1.00 19.06 ?  311  TYR B HE1  1 
ATOM   10318 H HE2  . TYR B 1 345 ? -14.515 25.566  59.235 1.00 21.44 ?  311  TYR B HE2  1 
ATOM   10319 H HH   . TYR B 1 345 ? -13.011 24.930  60.844 1.00 25.48 ?  311  TYR B HH   1 
ATOM   10320 N N    . LEU B 1 346 ? -17.752 29.812  59.117 1.00 13.42 ?  312  LEU B N    1 
ATOM   10321 C CA   . LEU B 1 346 ? -16.707 30.611  58.496 1.00 13.66 ?  312  LEU B CA   1 
ATOM   10322 C C    . LEU B 1 346 ? -16.722 32.040  59.002 1.00 12.63 ?  312  LEU B C    1 
ATOM   10323 O O    . LEU B 1 346 ? -15.665 32.621  59.297 1.00 12.32 ?  312  LEU B O    1 
ATOM   10324 C CB   . LEU B 1 346 ? -16.819 30.543  56.968 1.00 12.74 ?  312  LEU B CB   1 
ATOM   10325 C CG   . LEU B 1 346 ? -16.681 29.170  56.340 1.00 12.70 ?  312  LEU B CG   1 
ATOM   10326 C CD1  . LEU B 1 346 ? -16.975 29.231  54.831 1.00 15.11 ?  312  LEU B CD1  1 
ATOM   10327 C CD2  . LEU B 1 346 ? -15.324 28.555  56.668 1.00 12.79 ?  312  LEU B CD2  1 
ATOM   10328 H H    . LEU B 1 346 ? -18.369 29.552  58.578 1.00 16.11 ?  312  LEU B H    1 
ATOM   10329 H HA   . LEU B 1 346 ? -15.844 30.236  58.732 1.00 16.39 ?  312  LEU B HA   1 
ATOM   10330 H HB2  . LEU B 1 346 ? -17.691 30.886  56.716 1.00 15.29 ?  312  LEU B HB2  1 
ATOM   10331 H HB3  . LEU B 1 346 ? -16.121 31.101  56.591 1.00 15.29 ?  312  LEU B HB3  1 
ATOM   10332 H HG   . LEU B 1 346 ? -17.342 28.569  56.718 1.00 15.24 ?  312  LEU B HG   1 
ATOM   10333 H HD11 . LEU B 1 346 ? -16.811 28.358  54.442 1.00 18.13 ?  312  LEU B HD11 1 
ATOM   10334 H HD12 . LEU B 1 346 ? -17.903 29.482  54.700 1.00 18.13 ?  312  LEU B HD12 1 
ATOM   10335 H HD13 . LEU B 1 346 ? -16.393 29.890  54.422 1.00 18.13 ?  312  LEU B HD13 1 
ATOM   10336 H HD21 . LEU B 1 346 ? -15.264 27.681  56.252 1.00 15.35 ?  312  LEU B HD21 1 
ATOM   10337 H HD22 . LEU B 1 346 ? -14.624 29.133  56.325 1.00 15.35 ?  312  LEU B HD22 1 
ATOM   10338 H HD23 . LEU B 1 346 ? -15.240 28.470  57.630 1.00 15.35 ?  312  LEU B HD23 1 
ATOM   10339 N N    . LEU B 1 347 ? -17.920 32.609  59.220 1.00 12.17 ?  313  LEU B N    1 
ATOM   10340 C CA   . LEU B 1 347 ? -17.973 33.937  59.802 1.00 13.20 ?  313  LEU B CA   1 
ATOM   10341 C C    . LEU B 1 347 ? -17.472 33.949  61.242 1.00 12.33 ?  313  LEU B C    1 
ATOM   10342 O O    . LEU B 1 347 ? -16.857 34.931  61.659 1.00 12.20 ?  313  LEU B O    1 
ATOM   10343 C CB   . LEU B 1 347 ? -19.380 34.530  59.762 1.00 14.18 ?  313  LEU B CB   1 
ATOM   10344 C CG   . LEU B 1 347 ? -19.878 34.821  58.346 1.00 12.80 ?  313  LEU B CG   1 
ATOM   10345 C CD1  . LEU B 1 347 ? -21.334 35.259  58.494 1.00 15.15 ?  313  LEU B CD1  1 
ATOM   10346 C CD2  . LEU B 1 347 ? -19.015 35.857  57.670 1.00 14.03 ?  313  LEU B CD2  1 
ATOM   10347 H H    . LEU B 1 347 ? -18.682 32.251  59.043 1.00 14.60 ?  313  LEU B H    1 
ATOM   10348 H HA   . LEU B 1 347 ? -17.403 34.501  59.257 1.00 15.84 ?  313  LEU B HA   1 
ATOM   10349 H HB2  . LEU B 1 347 ? -19.995 33.901  60.171 1.00 17.01 ?  313  LEU B HB2  1 
ATOM   10350 H HB3  . LEU B 1 347 ? -19.381 35.365  60.256 1.00 17.01 ?  313  LEU B HB3  1 
ATOM   10351 H HG   . LEU B 1 347 ? -19.826 34.045  57.767 1.00 15.36 ?  313  LEU B HG   1 
ATOM   10352 H HD11 . LEU B 1 347 ? -21.697 35.449  57.614 1.00 18.19 ?  313  LEU B HD11 1 
ATOM   10353 H HD12 . LEU B 1 347 ? -21.838 34.544  58.913 1.00 18.19 ?  313  LEU B HD12 1 
ATOM   10354 H HD13 . LEU B 1 347 ? -21.370 36.056  59.045 1.00 18.19 ?  313  LEU B HD13 1 
ATOM   10355 H HD21 . LEU B 1 347 ? -19.437 36.124  56.838 1.00 16.84 ?  313  LEU B HD21 1 
ATOM   10356 H HD22 . LEU B 1 347 ? -18.925 36.625  58.256 1.00 16.84 ?  313  LEU B HD22 1 
ATOM   10357 H HD23 . LEU B 1 347 ? -18.143 35.474  57.491 1.00 16.84 ?  313  LEU B HD23 1 
ATOM   10358 N N    . ALA B 1 348 ? -17.692 32.854  61.972 1.00 12.59 ?  314  ALA B N    1 
ATOM   10359 C CA   . ALA B 1 348 ? -17.175 32.785  63.331 1.00 12.96 ?  314  ALA B CA   1 
ATOM   10360 C C    . ALA B 1 348 ? -15.650 32.803  63.365 1.00 12.98 ?  314  ALA B C    1 
ATOM   10361 O O    . ALA B 1 348 ? -15.060 33.502  64.209 1.00 12.99 ?  314  ALA B O    1 
ATOM   10362 C CB   . ALA B 1 348 ? -17.686 31.520  64.005 1.00 15.45 ?  314  ALA B CB   1 
ATOM   10363 H H    . ALA B 1 348 ? -18.126 32.159  61.709 1.00 15.11 ?  314  ALA B H    1 
ATOM   10364 H HA   . ALA B 1 348 ? -17.494 33.561  63.818 1.00 15.56 ?  314  ALA B HA   1 
ATOM   10365 H HB1  . ALA B 1 348 ? -17.375 31.504  64.924 1.00 18.53 ?  314  ALA B HB1  1 
ATOM   10366 H HB2  . ALA B 1 348 ? -18.656 31.520  63.984 1.00 18.53 ?  314  ALA B HB2  1 
ATOM   10367 H HB3  . ALA B 1 348 ? -17.345 30.748  63.527 1.00 18.53 ?  314  ALA B HB3  1 
ATOM   10368 N N    . ILE B 1 349 ? -15.002 32.091  62.451 1.00 11.88 ?  315  ILE B N    1 
ATOM   10369 C CA   . ILE B 1 349 ? -13.539 32.179  62.357 1.00 11.81 ?  315  ILE B CA   1 
ATOM   10370 C C    . ILE B 1 349 ? -13.109 33.613  62.133 1.00 12.54 ?  315  ILE B C    1 
ATOM   10371 O O    . ILE B 1 349 ? -12.229 34.141  62.824 1.00 13.00 ?  315  ILE B O    1 
ATOM   10372 C CB   . ILE B 1 349 ? -13.040 31.291  61.225 1.00 11.62 ?  315  ILE B CB   1 
ATOM   10373 C CG1  . ILE B 1 349 ? -13.272 29.818  61.559 1.00 14.10 ?  315  ILE B CG1  1 
ATOM   10374 C CG2  . ILE B 1 349 ? -11.546 31.569  60.940 1.00 14.22 ?  315  ILE B CG2  1 
ATOM   10375 C CD1  . ILE B 1 349 ? -12.987 28.906  60.441 1.00 14.20 ?  315  ILE B CD1  1 
ATOM   10376 H H    . ILE B 1 349 ? -15.371 31.560  61.884 1.00 14.26 ?  315  ILE B H    1 
ATOM   10377 H HA   . ILE B 1 349 ? -13.157 31.872  63.195 1.00 14.17 ?  315  ILE B HA   1 
ATOM   10378 H HB   . ILE B 1 349 ? -13.546 31.501  60.424 1.00 13.95 ?  315  ILE B HB   1 
ATOM   10379 H HG12 . ILE B 1 349 ? -12.694 29.570  62.297 1.00 16.92 ?  315  ILE B HG12 1 
ATOM   10380 H HG13 . ILE B 1 349 ? -14.201 29.697  61.810 1.00 16.92 ?  315  ILE B HG13 1 
ATOM   10381 H HG21 . ILE B 1 349 ? -11.214 30.903  60.318 1.00 17.06 ?  315  ILE B HG21 1 
ATOM   10382 H HG22 . ILE B 1 349 ? -11.457 32.455  60.555 1.00 17.06 ?  315  ILE B HG22 1 
ATOM   10383 H HG23 . ILE B 1 349 ? -11.051 31.519  61.773 1.00 17.06 ?  315  ILE B HG23 1 
ATOM   10384 H HD11 . ILE B 1 349 ? -13.065 27.991  60.752 1.00 17.04 ?  315  ILE B HD11 1 
ATOM   10385 H HD12 . ILE B 1 349 ? -13.627 29.069  59.730 1.00 17.04 ?  315  ILE B HD12 1 
ATOM   10386 H HD13 . ILE B 1 349 ? -12.087 29.072  60.120 1.00 17.04 ?  315  ILE B HD13 1 
ATOM   10387 N N    . PHE B 1 350 ? -13.735 34.297  61.165 1.00 12.35 ?  316  PHE B N    1 
ATOM   10388 C CA   . PHE B 1 350 ? -13.414 35.692  60.899 1.00 12.24 ?  316  PHE B CA   1 
ATOM   10389 C C    . PHE B 1 350 ? -13.620 36.566  62.137 1.00 12.26 ?  316  PHE B C    1 
ATOM   10390 O O    . PHE B 1 350 ? -12.743 37.361  62.519 1.00 12.52 ?  316  PHE B O    1 
ATOM   10391 C CB   . PHE B 1 350 ? -14.315 36.185  59.759 1.00 12.00 ?  316  PHE B CB   1 
ATOM   10392 C CG   . PHE B 1 350 ? -14.224 37.658  59.545 1.00 11.42 ?  316  PHE B CG   1 
ATOM   10393 C CD1  . PHE B 1 350 ? -13.057 38.234  59.068 1.00 12.36 ?  316  PHE B CD1  1 
ATOM   10394 C CD2  . PHE B 1 350 ? -15.283 38.482  59.846 1.00 12.21 ?  316  PHE B CD2  1 
ATOM   10395 C CE1  . PHE B 1 350 ? -12.959 39.589  58.888 1.00 12.07 ?  316  PHE B CE1  1 
ATOM   10396 C CE2  . PHE B 1 350 ? -15.166 39.852  59.657 1.00 12.58 ?  316  PHE B CE2  1 
ATOM   10397 C CZ   . PHE B 1 350 ? -14.012 40.394  59.163 1.00 14.58 ?  316  PHE B CZ   1 
ATOM   10398 H H    . PHE B 1 350 ? -14.346 33.973  60.654 1.00 14.82 ?  316  PHE B H    1 
ATOM   10399 H HA   . PHE B 1 350 ? -12.482 35.762  60.641 1.00 14.69 ?  316  PHE B HA   1 
ATOM   10400 H HB2  . PHE B 1 350 ? -14.051 35.746  58.936 1.00 14.40 ?  316  PHE B HB2  1 
ATOM   10401 H HB3  . PHE B 1 350 ? -15.237 35.969  59.970 1.00 14.40 ?  316  PHE B HB3  1 
ATOM   10402 H HD1  . PHE B 1 350 ? -12.329 37.691  58.866 1.00 14.83 ?  316  PHE B HD1  1 
ATOM   10403 H HD2  . PHE B 1 350 ? -16.075 38.122  60.176 1.00 14.65 ?  316  PHE B HD2  1 
ATOM   10404 H HE1  . PHE B 1 350 ? -12.164 39.957  58.576 1.00 14.49 ?  316  PHE B HE1  1 
ATOM   10405 H HE2  . PHE B 1 350 ? -15.881 40.408  59.869 1.00 15.10 ?  316  PHE B HE2  1 
ATOM   10406 H HZ   . PHE B 1 350 ? -13.952 41.310  59.016 1.00 17.50 ?  316  PHE B HZ   1 
ATOM   10407 N N    . LEU B 1 351 ? -14.775 36.419  62.800 1.00 12.28 ?  317  LEU B N    1 
ATOM   10408 C CA   . LEU B 1 351 ? -15.109 37.290  63.920 1.00 13.54 ?  317  LEU B CA   1 
ATOM   10409 C C    . LEU B 1 351 ? -14.211 37.064  65.132 1.00 13.33 ?  317  LEU B C    1 
ATOM   10410 O O    . LEU B 1 351 ? -14.015 38.001  65.919 1.00 13.67 ?  317  LEU B O    1 
ATOM   10411 C CB   . LEU B 1 351 ? -16.587 37.150  64.288 1.00 14.03 ?  317  LEU B CB   1 
ATOM   10412 C CG   . LEU B 1 351 ? -17.565 37.749  63.247 1.00 13.73 ?  317  LEU B CG   1 
ATOM   10413 C CD1  . LEU B 1 351 ? -19.002 37.296  63.581 1.00 18.75 ?  317  LEU B CD1  1 
ATOM   10414 C CD2  . LEU B 1 351 ? -17.513 39.261  63.144 1.00 14.90 ?  317  LEU B CD2  1 
ATOM   10415 H H    . LEU B 1 351 ? -15.373 35.828  62.619 1.00 14.73 ?  317  LEU B H    1 
ATOM   10416 H HA   . LEU B 1 351 ? -14.969 38.208  63.638 1.00 16.25 ?  317  LEU B HA   1 
ATOM   10417 H HB2  . LEU B 1 351 ? -16.794 36.206  64.378 1.00 16.84 ?  317  LEU B HB2  1 
ATOM   10418 H HB3  . LEU B 1 351 ? -16.740 37.604  65.131 1.00 16.84 ?  317  LEU B HB3  1 
ATOM   10419 H HG   . LEU B 1 351 ? -17.292 37.419  62.377 1.00 16.47 ?  317  LEU B HG   1 
ATOM   10420 H HD11 . LEU B 1 351 ? -19.617 37.715  62.959 1.00 22.49 ?  317  LEU B HD11 1 
ATOM   10421 H HD12 . LEU B 1 351 ? -19.056 36.331  63.501 1.00 22.49 ?  317  LEU B HD12 1 
ATOM   10422 H HD13 . LEU B 1 351 ? -19.214 37.565  64.489 1.00 22.49 ?  317  LEU B HD13 1 
ATOM   10423 H HD21 . LEU B 1 351 ? -18.133 39.552  62.457 1.00 17.88 ?  317  LEU B HD21 1 
ATOM   10424 H HD22 . LEU B 1 351 ? -17.764 39.645  63.999 1.00 17.88 ?  317  LEU B HD22 1 
ATOM   10425 H HD23 . LEU B 1 351 ? -16.611 39.531  62.913 1.00 17.88 ?  317  LEU B HD23 1 
ATOM   10426 N N    . ILE B 1 352 ? -13.707 35.849  65.314 1.00 13.09 ?  318  ILE B N    1 
ATOM   10427 C CA   . ILE B 1 352 ? -12.737 35.584  66.382 1.00 14.44 ?  318  ILE B CA   1 
ATOM   10428 C C    . ILE B 1 352 ? -11.459 36.373  66.148 1.00 17.18 ?  318  ILE B C    1 
ATOM   10429 O O    . ILE B 1 352 ? -10.734 36.692  67.101 1.00 16.35 ?  318  ILE B O    1 
ATOM   10430 C CB   . ILE B 1 352 ? -12.541 34.050  66.456 1.00 14.47 ?  318  ILE B CB   1 
ATOM   10431 C CG1  . ILE B 1 352 ? -13.727 33.313  67.121 1.00 25.00 ?  318  ILE B CG1  1 
ATOM   10432 C CG2  . ILE B 1 352 ? -11.206 33.676  67.118 1.00 23.56 ?  318  ILE B CG2  1 
ATOM   10433 C CD1  . ILE B 1 352 ? -14.321 33.903  68.322 1.00 24.33 ?  318  ILE B CD1  1 
ATOM   10434 H H    . ILE B 1 352 ? -13.905 35.161  64.838 1.00 15.71 ?  318  ILE B H    1 
ATOM   10435 H HA   . ILE B 1 352 ? -13.062 35.885  67.245 1.00 17.33 ?  318  ILE B HA   1 
ATOM   10436 H HB   . ILE B 1 352 ? -12.515 33.747  65.535 1.00 17.37 ?  318  ILE B HB   1 
ATOM   10437 H HG12 . ILE B 1 352 ? -14.438 33.247  66.464 1.00 30.00 ?  318  ILE B HG12 1 
ATOM   10438 H HG13 . ILE B 1 352 ? -13.421 32.427  67.369 1.00 30.00 ?  318  ILE B HG13 1 
ATOM   10439 H HG21 . ILE B 1 352 ? -11.195 32.720  67.287 1.00 28.27 ?  318  ILE B HG21 1 
ATOM   10440 H HG22 . ILE B 1 352 ? -10.480 33.914  66.521 1.00 28.27 ?  318  ILE B HG22 1 
ATOM   10441 H HG23 . ILE B 1 352 ? -11.121 34.161  67.953 1.00 28.27 ?  318  ILE B HG23 1 
ATOM   10442 H HD11 . ILE B 1 352 ? -14.844 33.226  68.780 1.00 29.20 ?  318  ILE B HD11 1 
ATOM   10443 H HD12 . ILE B 1 352 ? -13.611 34.221  68.901 1.00 29.20 ?  318  ILE B HD12 1 
ATOM   10444 H HD13 . ILE B 1 352 ? -14.892 34.642  68.061 1.00 29.20 ?  318  ILE B HD13 1 
ATOM   10445 N N    . CYS B 1 353 ? -11.154 36.724  64.889 1.00 13.86 ?  319  CYS B N    1 
ATOM   10446 C CA   . CYS B 1 353 ? -9.929  37.436  64.534 1.00 14.02 ?  319  CYS B CA   1 
ATOM   10447 C C    . CYS B 1 353 ? -10.103 38.928  64.379 1.00 14.03 ?  319  CYS B C    1 
ATOM   10448 O O    . CYS B 1 353 ? -9.138  39.670  64.605 1.00 14.41 ?  319  CYS B O    1 
ATOM   10449 C CB   . CYS B 1 353 ? -9.367  36.911  63.214 1.00 14.06 ?  319  CYS B CB   1 
ATOM   10450 S SG   . CYS B 1 353 ? -8.902  35.193  63.217 1.00 13.93 ?  319  CYS B SG   1 
ATOM   10451 H H    . CYS B 1 353 ? -11.656 36.554  64.212 1.00 16.63 ?  319  CYS B H    1 
ATOM   10452 H HA   . CYS B 1 353 ? -9.289  37.272  65.243 1.00 16.82 ?  319  CYS B HA   1 
ATOM   10453 H HB2  . CYS B 1 353 ? -10.041 37.028  62.526 1.00 16.88 ?  319  CYS B HB2  1 
ATOM   10454 H HB3  . CYS B 1 353 ? -8.574  37.426  62.993 1.00 16.88 ?  319  CYS B HB3  1 
ATOM   10455 H HG   . CYS B 1 353 ? -9.875  34.526  63.436 1.00 16.71 ?  319  CYS B HG   1 
ATOM   10456 N N    . ALA B 1 354 ? -11.289 39.391  63.999 1.00 13.10 ?  320  ALA B N    1 
ATOM   10457 C CA   . ALA B 1 354 ? -11.464 40.704  63.407 1.00 12.61 ?  320  ALA B CA   1 
ATOM   10458 C C    . ALA B 1 354 ? -11.163 41.854  64.353 1.00 13.54 ?  320  ALA B C    1 
ATOM   10459 O O    . ALA B 1 354 ? -11.490 41.813  65.551 1.00 14.63 ?  320  ALA B O    1 
ATOM   10460 C CB   . ALA B 1 354 ? -12.902 40.845  62.934 1.00 14.13 ?  320  ALA B CB   1 
ATOM   10461 H H    . ALA B 1 354 ? -12.024 38.951  64.076 1.00 15.72 ?  320  ALA B H    1 
ATOM   10462 H HA   . ALA B 1 354 ? -10.837 40.778  62.671 1.00 15.13 ?  320  ALA B HA   1 
ATOM   10463 H HB1  . ALA B 1 354 ? -13.015 41.717  62.524 1.00 16.96 ?  320  ALA B HB1  1 
ATOM   10464 H HB2  . ALA B 1 354 ? -13.091 40.148  62.287 1.00 16.96 ?  320  ALA B HB2  1 
ATOM   10465 H HB3  . ALA B 1 354 ? -13.495 40.758  63.697 1.00 16.96 ?  320  ALA B HB3  1 
ATOM   10466 N N    . GLU B 1 355 ? -10.610 42.927  63.775 1.00 13.14 ?  321  GLU B N    1 
ATOM   10467 C CA   . GLU B 1 355 ? -10.529 44.230  64.408 1.00 13.30 ?  321  GLU B CA   1 
ATOM   10468 C C    . GLU B 1 355 ? -10.993 45.272  63.410 1.00 14.81 ?  321  GLU B C    1 
ATOM   10469 O O    . GLU B 1 355 ? -11.376 44.942  62.287 1.00 14.38 ?  321  GLU B O    1 
ATOM   10470 C CB   . GLU B 1 355 ? -9.116  44.511  64.925 1.00 14.95 ?  321  GLU B CB   1 
ATOM   10471 C CG   . GLU B 1 355 ? -8.664  43.541  65.989 1.00 14.81 ?  321  GLU B CG   1 
ATOM   10472 C CD   . GLU B 1 355 ? -9.439  43.668  67.303 1.00 15.39 ?  321  GLU B CD   1 
ATOM   10473 O OE1  . GLU B 1 355 ? -10.060 44.713  67.571 1.00 20.09 ?  321  GLU B OE1  1 
ATOM   10474 O OE2  . GLU B 1 355 ? -9.421  42.699  68.067 1.00 16.67 ?  321  GLU B OE2  1 
ATOM   10475 H H    . GLU B 1 355 ? -10.265 42.915  62.988 1.00 15.77 ?  321  GLU B H    1 
ATOM   10476 H HA   . GLU B 1 355 ? -11.122 44.264  65.175 1.00 15.96 ?  321  GLU B HA   1 
ATOM   10477 H HB2  . GLU B 1 355 ? -8.493  44.450  64.184 1.00 17.94 ?  321  GLU B HB2  1 
ATOM   10478 H HB3  . GLU B 1 355 ? -9.093  45.402  65.306 1.00 17.94 ?  321  GLU B HB3  1 
ATOM   10479 H HG2  . GLU B 1 355 ? -8.784  42.637  65.660 1.00 17.77 ?  321  GLU B HG2  1 
ATOM   10480 H HG3  . GLU B 1 355 ? -7.727  43.702  66.181 1.00 17.77 ?  321  GLU B HG3  1 
ATOM   10481 N N    . LYS B 1 356 ? -10.928 46.544  63.775 1.00 14.83 ?  322  LYS B N    1 
ATOM   10482 C CA   . LYS B 1 356 ? -11.171 47.598  62.803 1.00 14.48 ?  322  LYS B CA   1 
ATOM   10483 C C    . LYS B 1 356 ? -10.297 47.351  61.586 1.00 13.52 ?  322  LYS B C    1 
ATOM   10484 O O    . LYS B 1 356 ? -9.118  47.023  61.708 1.00 13.94 ?  322  LYS B O    1 
ATOM   10485 C CB   . LYS B 1 356 ? -10.855 48.961  63.428 1.00 16.34 ?  322  LYS B CB   1 
ATOM   10486 C CG   . LYS B 1 356 ? -11.395 50.135  62.630 1.00 17.62 ?  322  LYS B CG   1 
ATOM   10487 C CD   . LYS B 1 356 ? -11.229 51.455  63.385 1.00 20.26 ?  322  LYS B CD   1 
ATOM   10488 C CE   . LYS B 1 356 ? -11.931 52.576  62.651 1.00 23.39 ?  322  LYS B CE   1 
ATOM   10489 N NZ   . LYS B 1 356 ? -11.687 53.894  63.273 1.00 29.67 ?  322  LYS B NZ   1 
ATOM   10490 H H    . LYS B 1 356 ? -10.748 46.820  64.570 1.00 17.79 ?  322  LYS B H    1 
ATOM   10491 H HA   . LYS B 1 356 ? -12.102 47.608  62.532 1.00 17.38 ?  322  LYS B HA   1 
ATOM   10492 H HB2  . LYS B 1 356 ? -11.248 48.998  64.313 1.00 19.61 ?  322  LYS B HB2  1 
ATOM   10493 H HB3  . LYS B 1 356 ? -9.892  49.061  63.488 1.00 19.61 ?  322  LYS B HB3  1 
ATOM   10494 H HG2  . LYS B 1 356 ? -10.914 50.202  61.791 1.00 21.14 ?  322  LYS B HG2  1 
ATOM   10495 H HG3  . LYS B 1 356 ? -12.341 49.999  62.460 1.00 21.14 ?  322  LYS B HG3  1 
ATOM   10496 H HD2  . LYS B 1 356 ? -11.616 51.375  64.270 1.00 24.31 ?  322  LYS B HD2  1 
ATOM   10497 H HD3  . LYS B 1 356 ? -10.286 51.674  63.454 1.00 24.31 ?  322  LYS B HD3  1 
ATOM   10498 H HE2  . LYS B 1 356 ? -11.607 52.610  61.737 1.00 28.07 ?  322  LYS B HE2  1 
ATOM   10499 H HE3  . LYS B 1 356 ? -12.887 52.412  62.659 1.00 28.07 ?  322  LYS B HE3  1 
ATOM   10500 H HZ1  . LYS B 1 356 ? -12.131 54.526  62.832 1.00 35.61 ?  322  LYS B HZ1  1 
ATOM   10501 H HZ2  . LYS B 1 356 ? -11.961 53.886  64.120 1.00 35.61 ?  322  LYS B HZ2  1 
ATOM   10502 H HZ3  . LYS B 1 356 ? -10.817 54.084  63.253 1.00 35.61 ?  322  LYS B HZ3  1 
ATOM   10503 N N    . TYR B 1 357 ? -10.900 47.454  60.408 1.00 12.79 ?  323  TYR B N    1 
ATOM   10504 C CA   . TYR B 1 357 ? -10.224 47.269  59.113 1.00 13.27 ?  323  TYR B CA   1 
ATOM   10505 C C    . TYR B 1 357 ? -9.995  45.803  58.761 1.00 12.85 ?  323  TYR B C    1 
ATOM   10506 O O    . TYR B 1 357 ? -9.140  45.494  57.917 1.00 13.29 ?  323  TYR B O    1 
ATOM   10507 C CB   . TYR B 1 357 ? -8.939  48.087  59.003 1.00 14.18 ?  323  TYR B CB   1 
ATOM   10508 C CG   . TYR B 1 357 ? -9.108  49.541  59.397 1.00 15.38 ?  323  TYR B CG   1 
ATOM   10509 C CD1  . TYR B 1 357 ? -10.004 50.355  58.721 1.00 15.65 ?  323  TYR B CD1  1 
ATOM   10510 C CD2  . TYR B 1 357 ? -8.377  50.100  60.439 1.00 16.22 ?  323  TYR B CD2  1 
ATOM   10511 C CE1  . TYR B 1 357 ? -10.146 51.701  59.074 1.00 18.81 ?  323  TYR B CE1  1 
ATOM   10512 C CE2  . TYR B 1 357 ? -8.516  51.448  60.773 1.00 19.63 ?  323  TYR B CE2  1 
ATOM   10513 C CZ   . TYR B 1 357 ? -9.392  52.195  60.086 1.00 17.60 ?  323  TYR B CZ   1 
ATOM   10514 O OH   . TYR B 1 357 ? -9.518  53.559  60.428 1.00 22.67 ?  323  TYR B OH   1 
ATOM   10515 H H    . TYR B 1 357 ? -11.736 47.637  60.324 1.00 15.35 ?  323  TYR B H    1 
ATOM   10516 H HA   . TYR B 1 357 ? -10.813 47.610  58.421 1.00 15.92 ?  323  TYR B HA   1 
ATOM   10517 H HB2  . TYR B 1 357 ? -8.270  47.698  59.588 1.00 17.02 ?  323  TYR B HB2  1 
ATOM   10518 H HB3  . TYR B 1 357 ? -8.631  48.063  58.084 1.00 17.02 ?  323  TYR B HB3  1 
ATOM   10519 H HD1  . TYR B 1 357 ? -10.515 50.004  58.028 1.00 18.78 ?  323  TYR B HD1  1 
ATOM   10520 H HD2  . TYR B 1 357 ? -7.786  49.567  60.920 1.00 19.47 ?  323  TYR B HD2  1 
ATOM   10521 H HE1  . TYR B 1 357 ? -10.748 52.247  58.623 1.00 22.57 ?  323  TYR B HE1  1 
ATOM   10522 H HE2  . TYR B 1 357 ? -8.011  51.821  61.459 1.00 23.56 ?  323  TYR B HE2  1 
ATOM   10523 H HH   . TYR B 1 357 ? -10.102 53.924  59.947 1.00 27.21 ?  323  TYR B HH   1 
ATOM   10524 N N    . SER B 1 358 ? -10.750 44.901  59.372 1.00 12.49 ?  324  SER B N    1 
ATOM   10525 C CA   . SER B 1 358 ? -10.843 43.514  58.952 1.00 11.38 ?  324  SER B CA   1 
ATOM   10526 C C    . SER B 1 358 ? -12.140 43.336  58.172 1.00 12.19 ?  324  SER B C    1 
ATOM   10527 O O    . SER B 1 358 ? -13.206 43.787  58.594 1.00 13.35 ?  324  SER B O    1 
ATOM   10528 C CB   . SER B 1 358 ? -10.901 42.601  60.173 1.00 12.33 ?  324  SER B CB   1 
ATOM   10529 O OG   . SER B 1 358 ? -9.680  42.594  60.914 1.00 13.27 ?  324  SER B OG   1 
ATOM   10530 H H    . SER B 1 358 ? -11.236 45.076  60.060 1.00 14.99 ?  324  SER B H    1 
ATOM   10531 H HA   . SER B 1 358 ? -10.080 43.275  58.403 1.00 13.65 ?  324  SER B HA   1 
ATOM   10532 H HB2  . SER B 1 358 ? -11.613 42.909  60.755 1.00 14.80 ?  324  SER B HB2  1 
ATOM   10533 H HB3  . SER B 1 358 ? -11.085 41.697  59.874 1.00 14.80 ?  324  SER B HB3  1 
ATOM   10534 H HG   . SER B 1 358 ? -9.649  41.917  61.410 1.00 15.92 ?  324  SER B HG   1 
ATOM   10535 N N    . TYR B 1 359 ? -12.051 42.607  57.044 1.00 12.15 ?  325  TYR B N    1 
ATOM   10536 C CA   . TYR B 1 359 ? -13.169 42.430  56.123 1.00 11.62 ?  325  TYR B CA   1 
ATOM   10537 C C    . TYR B 1 359 ? -13.175 40.977  55.678 1.00 11.47 ?  325  TYR B C    1 
ATOM   10538 O O    . TYR B 1 359 ? -12.110 40.358  55.535 1.00 12.80 ?  325  TYR B O    1 
ATOM   10539 C CB   . TYR B 1 359 ? -12.990 43.357  54.892 1.00 11.00 ?  325  TYR B CB   1 
ATOM   10540 C CG   . TYR B 1 359 ? -12.801 44.817  55.231 1.00 12.01 ?  325  TYR B CG   1 
ATOM   10541 C CD1  . TYR B 1 359 ? -13.903 45.668  55.342 1.00 11.73 ?  325  TYR B CD1  1 
ATOM   10542 C CD2  . TYR B 1 359 ? -11.519 45.343  55.429 1.00 12.17 ?  325  TYR B CD2  1 
ATOM   10543 C CE1  . TYR B 1 359 ? -13.718 47.017  55.665 1.00 12.69 ?  325  TYR B CE1  1 
ATOM   10544 C CE2  . TYR B 1 359 ? -11.341 46.667  55.736 1.00 14.01 ?  325  TYR B CE2  1 
ATOM   10545 C CZ   . TYR B 1 359 ? -12.455 47.485  55.852 1.00 11.86 ?  325  TYR B CZ   1 
ATOM   10546 O OH   . TYR B 1 359 ? -12.171 48.810  56.201 1.00 14.03 ?  325  TYR B OH   1 
ATOM   10547 H H    . TYR B 1 359 ? -11.336 42.200  56.794 1.00 14.58 ?  325  TYR B H    1 
ATOM   10548 H HA   . TYR B 1 359 ? -14.018 42.631  56.547 1.00 13.95 ?  325  TYR B HA   1 
ATOM   10549 H HB2  . TYR B 1 359 ? -12.207 43.068  54.398 1.00 13.20 ?  325  TYR B HB2  1 
ATOM   10550 H HB3  . TYR B 1 359 ? -13.780 43.286  54.334 1.00 13.20 ?  325  TYR B HB3  1 
ATOM   10551 H HD1  . TYR B 1 359 ? -14.761 45.338  55.201 1.00 14.08 ?  325  TYR B HD1  1 
ATOM   10552 H HD2  . TYR B 1 359 ? -10.778 44.786  55.350 1.00 14.60 ?  325  TYR B HD2  1 
ATOM   10553 H HE1  . TYR B 1 359 ? -14.449 47.586  55.751 1.00 15.23 ?  325  TYR B HE1  1 
ATOM   10554 H HE2  . TYR B 1 359 ? -10.487 47.011  55.865 1.00 16.82 ?  325  TYR B HE2  1 
ATOM   10555 H HH   . TYR B 1 359 ? -12.852 49.289  56.088 1.00 16.84 ?  325  TYR B HH   1 
ATOM   10556 N N    . VAL B 1 360 ? -14.365 40.436  55.372 1.00 11.62 ?  326  VAL B N    1 
ATOM   10557 C CA   . VAL B 1 360 ? -14.482 39.015  55.036 1.00 12.28 ?  326  VAL B CA   1 
ATOM   10558 C C    . VAL B 1 360 ? -15.144 38.809  53.672 1.00 12.66 ?  326  VAL B C    1 
ATOM   10559 O O    . VAL B 1 360 ? -16.030 39.568  53.270 1.00 12.33 ?  326  VAL B O    1 
ATOM   10560 C CB   . VAL B 1 360 ? -15.240 38.243  56.159 1.00 12.10 ?  326  VAL B CB   1 
ATOM   10561 C CG1  . VAL B 1 360 ? -16.722 38.660  56.227 1.00 14.05 ?  326  VAL B CG1  1 
ATOM   10562 C CG2  . VAL B 1 360 ? -15.146 36.752  55.989 1.00 12.48 ?  326  VAL B CG2  1 
ATOM   10563 H H    . VAL B 1 360 ? -15.108 40.870  55.355 1.00 13.94 ?  326  VAL B H    1 
ATOM   10564 H HA   . VAL B 1 360 ? -13.587 38.652  54.940 1.00 14.73 ?  326  VAL B HA   1 
ATOM   10565 H HB   . VAL B 1 360 ? -14.809 38.477  56.995 1.00 14.52 ?  326  VAL B HB   1 
ATOM   10566 H HG11 . VAL B 1 360 ? -17.123 38.272  57.020 1.00 16.86 ?  326  VAL B HG11 1 
ATOM   10567 H HG12 . VAL B 1 360 ? -16.776 39.628  56.268 1.00 16.86 ?  326  VAL B HG12 1 
ATOM   10568 H HG13 . VAL B 1 360 ? -17.178 38.337  55.434 1.00 16.86 ?  326  VAL B HG13 1 
ATOM   10569 H HG21 . VAL B 1 360 ? -15.421 36.323  56.814 1.00 14.97 ?  326  VAL B HG21 1 
ATOM   10570 H HG22 . VAL B 1 360 ? -15.730 36.480  55.264 1.00 14.97 ?  326  VAL B HG22 1 
ATOM   10571 H HG23 . VAL B 1 360 ? -14.229 36.515  55.782 1.00 14.97 ?  326  VAL B HG23 1 
ATOM   10572 N N    . TYR B 1 361 ? -14.726 37.758  52.976 1.00 11.22 ?  327  TYR B N    1 
ATOM   10573 C CA   . TYR B 1 361 ? -15.376 37.292  51.736 1.00 11.35 ?  327  TYR B CA   1 
ATOM   10574 C C    . TYR B 1 361 ? -15.492 35.778  51.758 1.00 11.45 ?  327  TYR B C    1 
ATOM   10575 O O    . TYR B 1 361 ? -14.475 35.071  51.682 1.00 12.13 ?  327  TYR B O    1 
ATOM   10576 C CB   . TYR B 1 361 ? -14.619 37.745  50.489 1.00 11.66 ?  327  TYR B CB   1 
ATOM   10577 C CG   . TYR B 1 361 ? -15.297 37.456  49.137 1.00 12.13 ?  327  TYR B CG   1 
ATOM   10578 C CD1  . TYR B 1 361 ? -16.635 37.204  49.028 1.00 12.68 ?  327  TYR B CD1  1 
ATOM   10579 C CD2  . TYR B 1 361 ? -14.548 37.523  47.978 1.00 13.20 ?  327  TYR B CD2  1 
ATOM   10580 C CE1  . TYR B 1 361 ? -17.246 36.976  47.792 1.00 12.91 ?  327  TYR B CE1  1 
ATOM   10581 C CE2  . TYR B 1 361 ? -15.144 37.304  46.735 1.00 12.33 ?  327  TYR B CE2  1 
ATOM   10582 C CZ   . TYR B 1 361 ? -16.486 37.073  46.654 1.00 11.70 ?  327  TYR B CZ   1 
ATOM   10583 O OH   . TYR B 1 361 ? -17.142 36.833  45.424 1.00 13.44 ?  327  TYR B OH   1 
ATOM   10584 H H    . TYR B 1 361 ? -14.048 37.279  53.200 1.00 13.47 ?  327  TYR B H    1 
ATOM   10585 H HA   . TYR B 1 361 ? -16.271 37.665  51.714 1.00 13.62 ?  327  TYR B HA   1 
ATOM   10586 H HB2  . TYR B 1 361 ? -14.492 38.706  50.545 1.00 14.00 ?  327  TYR B HB2  1 
ATOM   10587 H HB3  . TYR B 1 361 ? -13.758 37.297  50.479 1.00 14.00 ?  327  TYR B HB3  1 
ATOM   10588 H HD1  . TYR B 1 361 ? -17.155 37.183  49.798 1.00 15.21 ?  327  TYR B HD1  1 
ATOM   10589 H HD2  . TYR B 1 361 ? -13.639 37.715  48.026 1.00 15.84 ?  327  TYR B HD2  1 
ATOM   10590 H HE1  . TYR B 1 361 ? -18.150 36.763  47.741 1.00 15.49 ?  327  TYR B HE1  1 
ATOM   10591 H HE2  . TYR B 1 361 ? -14.626 37.316  45.962 1.00 14.80 ?  327  TYR B HE2  1 
ATOM   10592 H HH   . TYR B 1 361 ? -16.588 36.862  44.792 1.00 16.13 ?  327  TYR B HH   1 
ATOM   10593 N N    . LEU B 1 362 ? -16.723 35.302  51.833 1.00 11.19 ?  328  LEU B N    1 
ATOM   10594 C CA   . LEU B 1 362 ? -17.043 33.885  51.689 1.00 12.00 ?  328  LEU B CA   1 
ATOM   10595 C C    . LEU B 1 362 ? -17.443 33.658  50.238 1.00 13.29 ?  328  LEU B C    1 
ATOM   10596 O O    . LEU B 1 362 ? -18.475 34.166  49.776 1.00 13.10 ?  328  LEU B O    1 
ATOM   10597 C CB   . LEU B 1 362 ? -18.202 33.520  52.594 1.00 12.19 ?  328  LEU B CB   1 
ATOM   10598 C CG   . LEU B 1 362 ? -18.076 33.859  54.071 1.00 12.75 ?  328  LEU B CG   1 
ATOM   10599 C CD1  . LEU B 1 362 ? -19.219 33.236  54.827 1.00 14.74 ?  328  LEU B CD1  1 
ATOM   10600 C CD2  . LEU B 1 362 ? -16.727 33.453  54.597 1.00 14.62 ?  328  LEU B CD2  1 
ATOM   10601 H H    . LEU B 1 362 ? -17.415 35.794  51.970 1.00 13.43 ?  328  LEU B H    1 
ATOM   10602 H HA   . LEU B 1 362 ? -16.270 33.342  51.914 1.00 14.40 ?  328  LEU B HA   1 
ATOM   10603 H HB2  . LEU B 1 362 ? -18.990 33.983  52.267 1.00 14.62 ?  328  LEU B HB2  1 
ATOM   10604 H HB3  . LEU B 1 362 ? -18.333 32.561  52.536 1.00 14.62 ?  328  LEU B HB3  1 
ATOM   10605 H HG   . LEU B 1 362 ? -18.133 34.817  54.207 1.00 15.30 ?  328  LEU B HG   1 
ATOM   10606 H HD11 . LEU B 1 362 ? -19.093 33.394  55.776 1.00 17.69 ?  328  LEU B HD11 1 
ATOM   10607 H HD12 . LEU B 1 362 ? -20.050 33.641  54.532 1.00 17.69 ?  328  LEU B HD12 1 
ATOM   10608 H HD13 . LEU B 1 362 ? -19.234 32.283  54.648 1.00 17.69 ?  328  LEU B HD13 1 
ATOM   10609 H HD21 . LEU B 1 362 ? -16.750 33.465  55.567 1.00 17.54 ?  328  LEU B HD21 1 
ATOM   10610 H HD22 . LEU B 1 362 ? -16.520 32.560  54.281 1.00 17.54 ?  328  LEU B HD22 1 
ATOM   10611 H HD23 . LEU B 1 362 ? -16.061 34.080  54.274 1.00 17.54 ?  328  LEU B HD23 1 
ATOM   10612 N N    . HIS B 1 363 ? -16.666 32.899  49.507 1.00 12.44 ?  329  HIS B N    1 
ATOM   10613 C CA   . HIS B 1 363 ? -16.700 32.974  48.053 1.00 12.15 ?  329  HIS B CA   1 
ATOM   10614 C C    . HIS B 1 363 ? -16.890 31.595  47.410 1.00 11.36 ?  329  HIS B C    1 
ATOM   10615 O O    . HIS B 1 363 ? -16.663 30.530  47.999 1.00 12.86 ?  329  HIS B O    1 
ATOM   10616 C CB   . HIS B 1 363 ? -15.416 33.630  47.504 1.00 11.85 ?  329  HIS B CB   1 
ATOM   10617 C CG   . HIS B 1 363 ? -14.206 32.803  47.693 1.00 12.07 ?  329  HIS B CG   1 
ATOM   10618 N ND1  . HIS B 1 363 ? -13.873 31.779  46.843 1.00 12.41 ?  329  HIS B ND1  1 
ATOM   10619 C CD2  . HIS B 1 363 ? -13.232 32.863  48.633 1.00 12.78 ?  329  HIS B CD2  1 
ATOM   10620 C CE1  . HIS B 1 363 ? -12.752 31.214  47.282 1.00 14.63 ?  329  HIS B CE1  1 
ATOM   10621 N NE2  . HIS B 1 363 ? -12.346 31.877  48.354 1.00 13.88 ?  329  HIS B NE2  1 
ATOM   10622 H H    . HIS B 1 363 ? -16.105 32.328  49.823 1.00 14.92 ?  329  HIS B H    1 
ATOM   10623 H HA   . HIS B 1 363 ? -17.472 33.503  47.800 1.00 14.58 ?  329  HIS B HA   1 
ATOM   10624 H HB2  . HIS B 1 363 ? -15.526 33.783  46.553 1.00 14.22 ?  329  HIS B HB2  1 
ATOM   10625 H HB3  . HIS B 1 363 ? -15.275 34.473  47.962 1.00 14.22 ?  329  HIS B HB3  1 
ATOM   10626 H HD2  . HIS B 1 363 ? -13.182 33.467  49.338 1.00 15.33 ?  329  HIS B HD2  1 
ATOM   10627 H HE1  . HIS B 1 363 ? -12.326 30.480  46.901 1.00 17.55 ?  329  HIS B HE1  1 
ATOM   10628 H HE2  . HIS B 1 363 ? -11.632 31.709  48.803 1.00 16.66 ?  329  HIS B HE2  1 
ATOM   10629 N N    . ASP B 1 364 ? -17.303 31.672  46.137 1.00 11.75 ?  330  ASP B N    1 
ATOM   10630 C CA   . ASP B 1 364 ? -17.356 30.552  45.199 1.00 10.79 ?  330  ASP B CA   1 
ATOM   10631 C C    . ASP B 1 364 ? -16.508 30.927  44.001 1.00 12.40 ?  330  ASP B C    1 
ATOM   10632 O O    . ASP B 1 364 ? -16.961 30.903  42.856 1.00 13.40 ?  330  ASP B O    1 
ATOM   10633 C CB   . ASP B 1 364 ? -18.814 30.254  44.802 1.00 11.56 ?  330  ASP B CB   1 
ATOM   10634 C CG   . ASP B 1 364 ? -18.948 29.061  43.875 1.00 13.77 ?  330  ASP B CG   1 
ATOM   10635 O OD1  . ASP B 1 364 ? -18.109 28.146  43.909 1.00 14.86 ?  330  ASP B OD1  1 
ATOM   10636 O OD2  . ASP B 1 364 ? -19.941 29.030  43.128 1.00 13.31 ?  330  ASP B OD2  1 
ATOM   10637 H H    . ASP B 1 364 ? -17.572 32.405  45.776 1.00 14.09 ?  330  ASP B H    1 
ATOM   10638 H HA   . ASP B 1 364 ? -17.014 29.734  45.592 1.00 12.94 ?  330  ASP B HA   1 
ATOM   10639 H HB2  . ASP B 1 364 ? -19.326 30.067  45.604 1.00 13.87 ?  330  ASP B HB2  1 
ATOM   10640 H HB3  . ASP B 1 364 ? -19.180 31.028  44.346 1.00 13.87 ?  330  ASP B HB3  1 
ATOM   10641 N N    . GLY B 1 365 ? -15.244 31.233  44.261 1.00 11.69 ?  331  GLY B N    1 
ATOM   10642 C CA   . GLY B 1 365 ? -14.311 31.650  43.239 1.00 10.67 ?  331  GLY B CA   1 
ATOM   10643 C C    . GLY B 1 365 ? -14.429 33.119  42.902 1.00 11.78 ?  331  GLY B C    1 
ATOM   10644 O O    . GLY B 1 365 ? -15.409 33.772  43.227 1.00 13.64 ?  331  GLY B O    1 
ATOM   10645 H H    . GLY B 1 365 ? -14.897 31.204  45.047 1.00 14.03 ?  331  GLY B H    1 
ATOM   10646 H HA2  . GLY B 1 365 ? -13.406 31.480  43.543 1.00 12.81 ?  331  GLY B HA2  1 
ATOM   10647 H HA3  . GLY B 1 365 ? -14.473 31.139  42.430 1.00 12.81 ?  331  GLY B HA3  1 
ATOM   10648 N N    . TYR B 1 366 ? -13.420 33.638  42.224 1.00 11.44 ?  332  TYR B N    1 
ATOM   10649 C CA   . TYR B 1 366 ? -13.320 35.072  41.996 1.00 11.54 ?  332  TYR B CA   1 
ATOM   10650 C C    . TYR B 1 366 ? -13.898 35.506  40.664 1.00 13.15 ?  332  TYR B C    1 
ATOM   10651 O O    . TYR B 1 366 ? -14.062 36.708  40.433 1.00 16.25 ?  332  TYR B O    1 
ATOM   10652 C CB   . TYR B 1 366 ? -11.887 35.545  42.196 1.00 12.29 ?  332  TYR B CB   1 
ATOM   10653 C CG   . TYR B 1 366 ? -11.376 35.281  43.610 1.00 11.16 ?  332  TYR B CG   1 
ATOM   10654 C CD1  . TYR B 1 366 ? -12.182 35.434  44.711 1.00 13.10 ?  332  TYR B CD1  1 
ATOM   10655 C CD2  . TYR B 1 366 ? -10.063 34.940  43.826 1.00 12.60 ?  332  TYR B CD2  1 
ATOM   10656 C CE1  . TYR B 1 366 ? -11.719 35.171  46.003 1.00 12.31 ?  332  TYR B CE1  1 
ATOM   10657 C CE2  . TYR B 1 366 ? -9.563  34.690  45.133 1.00 11.40 ?  332  TYR B CE2  1 
ATOM   10658 C CZ   . TYR B 1 366 ? -10.407 34.843  46.203 1.00 12.37 ?  332  TYR B CZ   1 
ATOM   10659 O OH   . TYR B 1 366 ? -9.994  34.616  47.499 1.00 13.84 ?  332  TYR B OH   1 
ATOM   10660 H H    . TYR B 1 366 ? -12.778 33.179  41.882 1.00 13.72 ?  332  TYR B H    1 
ATOM   10661 H HA   . TYR B 1 366 ? -13.836 35.547  42.666 1.00 13.85 ?  332  TYR B HA   1 
ATOM   10662 H HB2  . TYR B 1 366 ? -11.309 35.076  41.574 1.00 14.75 ?  332  TYR B HB2  1 
ATOM   10663 H HB3  . TYR B 1 366 ? -11.843 36.500  42.033 1.00 14.75 ?  332  TYR B HB3  1 
ATOM   10664 H HD1  . TYR B 1 366 ? -13.059 35.719  44.594 1.00 15.71 ?  332  TYR B HD1  1 
ATOM   10665 H HD2  . TYR B 1 366 ? -9.486  34.872  43.099 1.00 15.12 ?  332  TYR B HD2  1 
ATOM   10666 H HE1  . TYR B 1 366 ? -12.302 35.220  46.726 1.00 14.77 ?  332  TYR B HE1  1 
ATOM   10667 H HE2  . TYR B 1 366 ? -8.680  34.426  45.259 1.00 13.67 ?  332  TYR B HE2  1 
ATOM   10668 H HH   . TYR B 1 366 ? -9.211  34.310  47.502 1.00 16.60 ?  332  TYR B HH   1 
ATOM   10669 N N    . LEU B 1 367 ? -14.234 34.586  39.783 1.00 11.25 ?  333  LEU B N    1 
ATOM   10670 C CA   . LEU B 1 367 ? -14.867 34.915  38.510 1.00 10.74 ?  333  LEU B CA   1 
ATOM   10671 C C    . LEU B 1 367 ? -16.369 35.100  38.729 1.00 11.30 ?  333  LEU B C    1 
ATOM   10672 O O    . LEU B 1 367 ? -17.076 34.168  39.118 1.00 11.84 ?  333  LEU B O    1 
ATOM   10673 C CB   . LEU B 1 367 ? -14.606 33.812  37.491 1.00 11.45 ?  333  LEU B CB   1 
ATOM   10674 C CG   . LEU B 1 367 ? -15.349 33.948  36.160 1.00 10.78 ?  333  LEU B CG   1 
ATOM   10675 C CD1  . LEU B 1 367 ? -15.021 35.245  35.465 1.00 13.39 ?  333  LEU B CD1  1 
ATOM   10676 C CD2  . LEU B 1 367 ? -15.007 32.778  35.258 1.00 12.71 ?  333  LEU B CD2  1 
ATOM   10677 H H    . LEU B 1 367 ? -14.105 33.743  39.895 1.00 13.50 ?  333  LEU B H    1 
ATOM   10678 H HA   . LEU B 1 367 ? -14.498 35.743  38.166 1.00 12.89 ?  333  LEU B HA   1 
ATOM   10679 H HB2  . LEU B 1 367 ? -13.657 33.802  37.291 1.00 13.74 ?  333  LEU B HB2  1 
ATOM   10680 H HB3  . LEU B 1 367 ? -14.871 32.966  37.884 1.00 13.74 ?  333  LEU B HB3  1 
ATOM   10681 H HG   . LEU B 1 367 ? -16.303 33.949  36.341 1.00 12.93 ?  333  LEU B HG   1 
ATOM   10682 H HD11 . LEU B 1 367 ? -15.486 35.274  34.615 1.00 16.07 ?  333  LEU B HD11 1 
ATOM   10683 H HD12 . LEU B 1 367 ? -15.308 35.984  36.024 1.00 16.07 ?  333  LEU B HD12 1 
ATOM   10684 H HD13 . LEU B 1 367 ? -14.063 35.292  35.321 1.00 16.07 ?  333  LEU B HD13 1 
ATOM   10685 H HD21 . LEU B 1 367 ? -15.545 32.831  34.453 1.00 15.26 ?  333  LEU B HD21 1 
ATOM   10686 H HD22 . LEU B 1 367 ? -14.065 32.820  35.030 1.00 15.26 ?  333  LEU B HD22 1 
ATOM   10687 H HD23 . LEU B 1 367 ? -15.196 31.951  35.728 1.00 15.26 ?  333  LEU B HD23 1 
ATOM   10688 N N    . ALA B 1 368 ? -16.850 36.326  38.501 1.00 11.93 ?  334  ALA B N    1 
ATOM   10689 C CA   . ALA B 1 368 ? -18.238 36.636  38.837 1.00 12.09 ?  334  ALA B CA   1 
ATOM   10690 C C    . ALA B 1 368 ? -19.242 35.716  38.163 1.00 12.30 ?  334  ALA B C    1 
ATOM   10691 O O    . ALA B 1 368 ? -20.202 35.265  38.801 1.00 14.10 ?  334  ALA B O    1 
ATOM   10692 C CB   . ALA B 1 368 ? -18.543 38.083  38.468 1.00 13.37 ?  334  ALA B CB   1 
ATOM   10693 H H    . ALA B 1 368 ? -16.404 36.978  38.161 1.00 14.32 ?  334  ALA B H    1 
ATOM   10694 H HA   . ALA B 1 368 ? -18.336 36.513  39.794 1.00 14.50 ?  334  ALA B HA   1 
ATOM   10695 H HB1  . ALA B 1 368 ? -19.486 38.255  38.618 1.00 16.04 ?  334  ALA B HB1  1 
ATOM   10696 H HB2  . ALA B 1 368 ? -18.007 38.670  39.022 1.00 16.04 ?  334  ALA B HB2  1 
ATOM   10697 H HB3  . ALA B 1 368 ? -18.327 38.222  37.532 1.00 16.04 ?  334  ALA B HB3  1 
ATOM   10698 N N    . THR B 1 369 ? -19.028 35.405  36.884 1.00 12.40 ?  335  THR B N    1 
ATOM   10699 C CA   . THR B 1 369 ? -20.008 34.648  36.109 1.00 13.24 ?  335  THR B CA   1 
ATOM   10700 C C    . THR B 1 369 ? -20.007 33.160  36.440 1.00 13.97 ?  335  THR B C    1 
ATOM   10701 O O    . THR B 1 369 ? -20.859 32.408  35.934 1.00 15.40 ?  335  THR B O    1 
ATOM   10702 C CB   . THR B 1 369 ? -19.720 34.854  34.620 1.00 12.92 ?  335  THR B CB   1 
ATOM   10703 O OG1  . THR B 1 369 ? -18.317 34.687  34.379 1.00 12.82 ?  335  THR B OG1  1 
ATOM   10704 C CG2  . THR B 1 369 ? -20.100 36.237  34.157 1.00 15.55 ?  335  THR B CG2  1 
ATOM   10705 H H    . THR B 1 369 ? -18.322 35.621  36.443 1.00 14.88 ?  335  THR B H    1 
ATOM   10706 H HA   . THR B 1 369 ? -20.899 34.980  36.301 1.00 15.89 ?  335  THR B HA   1 
ATOM   10707 H HB   . THR B 1 369 ? -20.243 34.207  34.121 1.00 15.50 ?  335  THR B HB   1 
ATOM   10708 H HG1  . THR B 1 369 ? -18.096 33.888  34.512 1.00 15.38 ?  335  THR B HG1  1 
ATOM   10709 H HG21 . THR B 1 369 ? -19.849 36.356  33.227 1.00 18.67 ?  335  THR B HG21 1 
ATOM   10710 H HG22 . THR B 1 369 ? -21.057 36.365  34.244 1.00 18.67 ?  335  THR B HG22 1 
ATOM   10711 H HG23 . THR B 1 369 ? -19.643 36.904  34.693 1.00 18.67 ?  335  THR B HG23 1 
ATOM   10712 N N    . ASN B 1 370 ? -19.102 32.681  37.304 1.00 11.56 ?  336  ASN B N    1 
ATOM   10713 C CA   . ASN B 1 370 ? -19.036 31.282  37.701 1.00 12.89 ?  336  ASN B CA   1 
ATOM   10714 C C    . ASN B 1 370 ? -19.281 31.092  39.191 1.00 12.31 ?  336  ASN B C    1 
ATOM   10715 O O    . ASN B 1 370 ? -19.047 29.990  39.711 1.00 14.01 ?  336  ASN B O    1 
ATOM   10716 C CB   . ASN B 1 370 ? -17.720 30.645  37.271 1.00 13.45 ?  336  ASN B CB   1 
ATOM   10717 C CG   . ASN B 1 370 ? -17.786 29.123  37.240 1.00 14.62 ?  336  ASN B CG   1 
ATOM   10718 O OD1  . ASN B 1 370 ? -18.769 28.523  36.797 1.00 15.13 ?  336  ASN B OD1  1 
ATOM   10719 N ND2  . ASN B 1 370 ? -16.711 28.496  37.695 1.00 15.94 ?  336  ASN B ND2  1 
ATOM   10720 H H    . ASN B 1 370 ? -18.501 33.167  37.681 1.00 13.87 ?  336  ASN B H    1 
ATOM   10721 H HA   . ASN B 1 370 ? -19.734 30.797  37.233 1.00 15.47 ?  336  ASN B HA   1 
ATOM   10722 H HB2  . ASN B 1 370 ? -17.496 30.954  36.379 1.00 16.14 ?  336  ASN B HB2  1 
ATOM   10723 H HB3  . ASN B 1 370 ? -17.024 30.903  37.895 1.00 16.14 ?  336  ASN B HB3  1 
ATOM   10724 H HD21 . ASN B 1 370 ? -16.686 27.636  37.704 1.00 19.13 ?  336  ASN B HD21 1 
ATOM   10725 H HD22 . ASN B 1 370 ? -16.038 28.948  37.982 1.00 19.13 ?  336  ASN B HD22 1 
ATOM   10726 N N    . SER B 1 371 ? -19.701 32.134  39.897 1.00 11.70 ?  337  SER B N    1 
ATOM   10727 C CA   . SER B 1 371 ? -19.891 32.097  41.342 1.00 12.51 ?  337  SER B CA   1 
ATOM   10728 C C    . SER B 1 371 ? -21.361 32.046  41.702 1.00 14.14 ?  337  SER B C    1 
ATOM   10729 O O    . SER B 1 371 ? -22.128 32.946  41.309 1.00 14.02 ?  337  SER B O    1 
ATOM   10730 C CB   . SER B 1 371 ? -19.289 33.336  41.990 1.00 13.18 ?  337  SER B CB   1 
ATOM   10731 O OG   . SER B 1 371 ? -19.765 33.382  43.323 1.00 13.68 ?  337  SER B OG   1 
ATOM   10732 H H    . SER B 1 371 ? -19.888 32.898  39.551 1.00 14.04 ?  337  SER B H    1 
ATOM   10733 H HA   . SER B 1 371 ? -19.465 31.292  41.677 1.00 15.01 ?  337  SER B HA   1 
ATOM   10734 H HB2  . SER B 1 371 ? -18.321 33.274  41.987 1.00 15.81 ?  337  SER B HB2  1 
ATOM   10735 H HB3  . SER B 1 371 ? -19.572 34.130  41.511 1.00 15.81 ?  337  SER B HB3  1 
ATOM   10736 H HG   . SER B 1 371 ? -19.368 33.988  43.749 1.00 16.42 ?  337  SER B HG   1 
ATOM   10737 N N    . ALA B 1 372 ? -21.737 31.057  42.521 1.00 13.18 ?  338  ALA B N    1 
ATOM   10738 C CA   . ALA B 1 372 ? -23.126 30.962  42.967 1.00 13.37 ?  338  ALA B CA   1 
ATOM   10739 C C    . ALA B 1 372 ? -23.511 32.018  43.978 1.00 14.30 ?  338  ALA B C    1 
ATOM   10740 O O    . ALA B 1 372 ? -24.704 32.144  44.286 1.00 18.94 ?  338  ALA B O    1 
ATOM   10741 C CB   . ALA B 1 372 ? -23.379 29.572  43.562 1.00 16.96 ?  338  ALA B CB   1 
ATOM   10742 H H    . ALA B 1 372 ? -21.217 30.444  42.825 1.00 15.81 ?  338  ALA B H    1 
ATOM   10743 H HA   . ALA B 1 372 ? -23.701 31.080  42.195 1.00 16.04 ?  338  ALA B HA   1 
ATOM   10744 H HB1  . ALA B 1 372 ? -24.284 29.537  43.909 1.00 20.35 ?  338  ALA B HB1  1 
ATOM   10745 H HB2  . ALA B 1 372 ? -23.267 28.905  42.866 1.00 20.35 ?  338  ALA B HB2  1 
ATOM   10746 H HB3  . ALA B 1 372 ? -22.743 29.414  44.277 1.00 20.35 ?  338  ALA B HB3  1 
ATOM   10747 N N    . VAL B 1 373 ? -22.559 32.749  44.542 1.00 13.85 ?  339  VAL B N    1 
ATOM   10748 C CA   . VAL B 1 373 ? -22.862 33.770  45.531 1.00 15.10 ?  339  VAL B CA   1 
ATOM   10749 C C    . VAL B 1 373 ? -22.717 35.176  44.974 1.00 15.14 ?  339  VAL B C    1 
ATOM   10750 O O    . VAL B 1 373 ? -22.951 36.156  45.697 1.00 17.11 ?  339  VAL B O    1 
ATOM   10751 C CB   . VAL B 1 373 ? -22.056 33.601  46.841 1.00 16.51 ?  339  VAL B CB   1 
ATOM   10752 C CG1  . VAL B 1 373 ? -22.383 32.277  47.478 1.00 17.69 ?  339  VAL B CG1  1 
ATOM   10753 C CG2  . VAL B 1 373 ? -20.542 33.775  46.598 1.00 14.88 ?  339  VAL B CG2  1 
ATOM   10754 H H    . VAL B 1 373 ? -21.721 32.669  44.366 1.00 16.62 ?  339  VAL B H    1 
ATOM   10755 H HA   . VAL B 1 373 ? -23.792 33.658  45.781 1.00 18.12 ?  339  VAL B HA   1 
ATOM   10756 H HB   . VAL B 1 373 ? -22.311 34.300  47.464 1.00 19.82 ?  339  VAL B HB   1 
ATOM   10757 H HG11 . VAL B 1 373 ? -21.858 32.178  48.287 1.00 21.23 ?  339  VAL B HG11 1 
ATOM   10758 H HG12 . VAL B 1 373 ? -23.329 32.255  47.692 1.00 21.23 ?  339  VAL B HG12 1 
ATOM   10759 H HG13 . VAL B 1 373 ? -22.168 31.565  46.855 1.00 21.23 ?  339  VAL B HG13 1 
ATOM   10760 H HG21 . VAL B 1 373 ? -20.074 33.675  47.442 1.00 17.85 ?  339  VAL B HG21 1 
ATOM   10761 H HG22 . VAL B 1 373 ? -20.243 33.097  45.972 1.00 17.85 ?  339  VAL B HG22 1 
ATOM   10762 H HG23 . VAL B 1 373 ? -20.380 34.658  46.232 1.00 17.85 ?  339  VAL B HG23 1 
ATOM   10763 N N    . TRP B 1 374 ? -22.389 35.318  43.693 1.00 15.61 ?  340  TRP B N    1 
ATOM   10764 C CA   . TRP B 1 374 ? -22.284 36.630  43.084 1.00 16.21 ?  340  TRP B CA   1 
ATOM   10765 C C    . TRP B 1 374 ? -23.622 37.325  43.187 1.00 15.22 ?  340  TRP B C    1 
ATOM   10766 O O    . TRP B 1 374 ? -24.672 36.753  42.891 1.00 16.85 ?  340  TRP B O    1 
ATOM   10767 C CB   . TRP B 1 374 ? -21.897 36.455  41.620 1.00 18.79 ?  340  TRP B CB   1 
ATOM   10768 C CG   . TRP B 1 374 ? -21.804 37.735  40.810 1.00 16.15 ?  340  TRP B CG   1 
ATOM   10769 C CD1  . TRP B 1 374 ? -22.531 38.018  39.678 1.00 18.28 ?  340  TRP B CD1  1 
ATOM   10770 C CD2  . TRP B 1 374 ? -20.934 38.844  41.032 1.00 16.10 ?  340  TRP B CD2  1 
ATOM   10771 N NE1  . TRP B 1 374 ? -22.166 39.272  39.205 1.00 15.53 ?  340  TRP B NE1  1 
ATOM   10772 C CE2  . TRP B 1 374 ? -21.203 39.786  40.018 1.00 14.06 ?  340  TRP B CE2  1 
ATOM   10773 C CE3  . TRP B 1 374 ? -19.971 39.171  42.006 1.00 14.53 ?  340  TRP B CE3  1 
ATOM   10774 C CZ2  . TRP B 1 374 ? -20.520 40.984  39.940 1.00 15.97 ?  340  TRP B CZ2  1 
ATOM   10775 C CZ3  . TRP B 1 374 ? -19.331 40.354  41.933 1.00 16.06 ?  340  TRP B CZ3  1 
ATOM   10776 C CH2  . TRP B 1 374 ? -19.572 41.256  40.887 1.00 15.68 ?  340  TRP B CH2  1 
ATOM   10777 H H    . TRP B 1 374 ? -22.224 34.667  43.156 1.00 18.73 ?  340  TRP B H    1 
ATOM   10778 H HA   . TRP B 1 374 ? -21.610 37.171  43.525 1.00 19.45 ?  340  TRP B HA   1 
ATOM   10779 H HB2  . TRP B 1 374 ? -21.028 36.026  41.583 1.00 22.55 ?  340  TRP B HB2  1 
ATOM   10780 H HB3  . TRP B 1 374 ? -22.563 35.892  41.194 1.00 22.55 ?  340  TRP B HB3  1 
ATOM   10781 H HD1  . TRP B 1 374 ? -23.166 37.460  39.291 1.00 21.93 ?  340  TRP B HD1  1 
ATOM   10782 H HE1  . TRP B 1 374 ? -22.494 39.660  38.511 1.00 18.63 ?  340  TRP B HE1  1 
ATOM   10783 H HE3  . TRP B 1 374 ? -19.778 38.576  42.694 1.00 17.44 ?  340  TRP B HE3  1 
ATOM   10784 H HZ2  . TRP B 1 374 ? -20.701 41.592  39.259 1.00 19.17 ?  340  TRP B HZ2  1 
ATOM   10785 H HZ3  . TRP B 1 374 ? -18.715 40.578  42.592 1.00 19.28 ?  340  TRP B HZ3  1 
ATOM   10786 H HH2  . TRP B 1 374 ? -19.083 42.045  40.837 1.00 18.81 ?  340  TRP B HH2  1 
ATOM   10787 N N    . LEU B 1 375 ? -23.578 38.585  43.640 1.00 15.24 ?  341  LEU B N    1 
ATOM   10788 C CA   . LEU B 1 375 ? -24.725 39.468  43.850 1.00 18.46 ?  341  LEU B CA   1 
ATOM   10789 C C    . LEU B 1 375 ? -25.537 39.103  45.096 1.00 20.09 ?  341  LEU B C    1 
ATOM   10790 O O    . LEU B 1 375 ? -26.532 39.776  45.385 1.00 23.37 ?  341  LEU B O    1 
ATOM   10791 C CB   . LEU B 1 375 ? -25.637 39.600  42.625 1.00 19.46 ?  341  LEU B CB   1 
ATOM   10792 C CG   . LEU B 1 375 ? -24.989 40.249  41.423 1.00 18.61 ?  341  LEU B CG   1 
ATOM   10793 C CD1  . LEU B 1 375 ? -25.815 40.113  40.158 1.00 22.45 ?  341  LEU B CD1  1 
ATOM   10794 C CD2  . LEU B 1 375 ? -24.764 41.717  41.684 1.00 20.63 ?  341  LEU B CD2  1 
ATOM   10795 H H    . LEU B 1 375 ? -22.838 38.973  43.844 1.00 18.28 ?  341  LEU B H    1 
ATOM   10796 H HA   . LEU B 1 375 ? -24.374 40.359  44.004 1.00 22.15 ?  341  LEU B HA   1 
ATOM   10797 H HB2  . LEU B 1 375 ? -25.926 38.713  42.359 1.00 23.35 ?  341  LEU B HB2  1 
ATOM   10798 H HB3  . LEU B 1 375 ? -26.406 40.139  42.870 1.00 23.35 ?  341  LEU B HB3  1 
ATOM   10799 H HG   . LEU B 1 375 ? -24.146 39.791  41.277 1.00 22.33 ?  341  LEU B HG   1 
ATOM   10800 H HD11 . LEU B 1 375 ? -25.322 40.496  39.416 1.00 26.93 ?  341  LEU B HD11 1 
ATOM   10801 H HD12 . LEU B 1 375 ? -25.985 39.172  39.992 1.00 26.93 ?  341  LEU B HD12 1 
ATOM   10802 H HD13 . LEU B 1 375 ? -26.654 40.585  40.277 1.00 26.93 ?  341  LEU B HD13 1 
ATOM   10803 H HD21 . LEU B 1 375 ? -24.564 42.160  40.845 1.00 24.75 ?  341  LEU B HD21 1 
ATOM   10804 H HD22 . LEU B 1 375 ? -25.568 42.094  42.074 1.00 24.75 ?  341  LEU B HD22 1 
ATOM   10805 H HD23 . LEU B 1 375 ? -24.020 41.818  42.298 1.00 24.75 ?  341  LEU B HD23 1 
ATOM   10806 N N    . HIS B 1 376 ? -25.150 38.097  45.858 1.00 16.36 ?  342  HIS B N    1 
ATOM   10807 C CA   . HIS B 1 376 ? -25.954 37.612  46.961 1.00 16.03 ?  342  HIS B CA   1 
ATOM   10808 C C    . HIS B 1 376 ? -25.507 38.219  48.280 1.00 18.16 ?  342  HIS B C    1 
ATOM   10809 O O    . HIS B 1 376 ? -24.310 38.458  48.490 1.00 21.95 ?  342  HIS B O    1 
ATOM   10810 C CB   . HIS B 1 376 ? -25.834 36.090  47.112 1.00 18.24 ?  342  HIS B CB   1 
ATOM   10811 C CG   . HIS B 1 376 ? -26.780 35.516  48.125 1.00 18.89 ?  342  HIS B CG   1 
ATOM   10812 N ND1  . HIS B 1 376 ? -28.145 35.485  47.912 1.00 21.85 ?  342  HIS B ND1  1 
ATOM   10813 C CD2  . HIS B 1 376 ? -26.577 34.927  49.328 1.00 18.12 ?  342  HIS B CD2  1 
ATOM   10814 C CE1  . HIS B 1 376 ? -28.737 34.937  48.961 1.00 22.54 ?  342  HIS B CE1  1 
ATOM   10815 N NE2  . HIS B 1 376 ? -27.802 34.591  49.831 1.00 21.81 ?  342  HIS B NE2  1 
ATOM   10816 H H    . HIS B 1 376 ? -24.410 37.671  45.754 1.00 19.64 ?  342  HIS B H    1 
ATOM   10817 H HA   . HIS B 1 376 ? -26.874 37.861  46.779 1.00 19.24 ?  342  HIS B HA   1 
ATOM   10818 H HB2  . HIS B 1 376 ? -26.025 35.674  46.257 1.00 21.89 ?  342  HIS B HB2  1 
ATOM   10819 H HB3  . HIS B 1 376 ? -24.931 35.873  47.392 1.00 21.89 ?  342  HIS B HB3  1 
ATOM   10820 H HD2  . HIS B 1 376 ? -25.754 34.778  49.736 1.00 21.75 ?  342  HIS B HD2  1 
ATOM   10821 H HE1  . HIS B 1 376 ? -29.653 34.816  49.068 1.00 27.05 ?  342  HIS B HE1  1 
ATOM   10822 H HE2  . HIS B 1 376 ? -27.944 34.216  50.592 1.00 26.17 ?  342  HIS B HE2  1 
ATOM   10823 N N    . GLN B 1 377 ? -26.449 38.403  49.183 1.00 16.92 ?  343  GLN B N    1 
ATOM   10824 C CA   . GLN B 1 377 ? -26.211 38.833  50.569 1.00 17.06 ?  343  GLN B CA   1 
ATOM   10825 C C    . GLN B 1 377 ? -26.831 37.802  51.504 1.00 18.12 ?  343  GLN B C    1 
ATOM   10826 O O    . GLN B 1 377 ? -28.055 37.614  51.519 1.00 20.42 ?  343  GLN B O    1 
ATOM   10827 C CB   . GLN B 1 377 ? -26.811 40.216  50.821 1.00 26.81 ?  343  GLN B CB   1 
ATOM   10828 C CG   . GLN B 1 377 ? -26.482 40.794  52.177 1.00 44.73 ?  343  GLN B CG   1 
ATOM   10829 C CD   . GLN B 1 377 ? -26.063 42.246  52.101 1.00 50.63 ?  343  GLN B CD   1 
ATOM   10830 O OE1  . GLN B 1 377 ? -26.855 43.097  51.693 1.00 46.91 ?  343  GLN B OE1  1 
ATOM   10831 N NE2  . GLN B 1 377 ? -24.807 42.541  52.487 1.00 37.71 ?  343  GLN B NE2  1 
ATOM   10832 H H    . GLN B 1 377 ? -27.284 38.280  49.019 1.00 20.31 ?  343  GLN B H    1 
ATOM   10833 H HA   . GLN B 1 377 ? -25.256 38.871  50.734 1.00 20.48 ?  343  GLN B HA   1 
ATOM   10834 H HB2  . GLN B 1 377 ? -26.471 40.829  50.150 1.00 32.17 ?  343  GLN B HB2  1 
ATOM   10835 H HB3  . GLN B 1 377 ? -27.776 40.153  50.754 1.00 32.17 ?  343  GLN B HB3  1 
ATOM   10836 H HG2  . GLN B 1 377 ? -27.266 40.736  52.745 1.00 53.67 ?  343  GLN B HG2  1 
ATOM   10837 H HG3  . GLN B 1 377 ? -25.751 40.289  52.568 1.00 53.67 ?  343  GLN B HG3  1 
ATOM   10838 H HE21 . GLN B 1 377 ? -24.283 41.917  52.761 1.00 45.25 ?  343  GLN B HE21 1 
ATOM   10839 H HE22 . GLN B 1 377 ? -24.529 43.355  52.459 1.00 45.25 ?  343  GLN B HE22 1 
ATOM   10840 N N    . PHE B 1 378 ? -25.992 37.084  52.256 1.00 15.77 ?  344  PHE B N    1 
ATOM   10841 C CA   . PHE B 1 378 ? -26.506 36.199  53.273 1.00 14.32 ?  344  PHE B CA   1 
ATOM   10842 C C    . PHE B 1 378 ? -27.156 37.008  54.387 1.00 15.10 ?  344  PHE B C    1 
ATOM   10843 O O    . PHE B 1 378 ? -26.811 38.153  54.630 1.00 15.06 ?  344  PHE B O    1 
ATOM   10844 C CB   . PHE B 1 378 ? -25.370 35.340  53.860 1.00 15.60 ?  344  PHE B CB   1 
ATOM   10845 C CG   . PHE B 1 378 ? -24.884 34.292  52.898 1.00 17.00 ?  344  PHE B CG   1 
ATOM   10846 C CD1  . PHE B 1 378 ? -25.648 33.182  52.644 1.00 18.35 ?  344  PHE B CD1  1 
ATOM   10847 C CD2  . PHE B 1 378 ? -23.682 34.441  52.256 1.00 20.09 ?  344  PHE B CD2  1 
ATOM   10848 C CE1  . PHE B 1 378 ? -25.208 32.218  51.732 1.00 18.00 ?  344  PHE B CE1  1 
ATOM   10849 C CE2  . PHE B 1 378 ? -23.242 33.471  51.357 1.00 24.29 ?  344  PHE B CE2  1 
ATOM   10850 C CZ   . PHE B 1 378 ? -24.021 32.380  51.103 1.00 19.30 ?  344  PHE B CZ   1 
ATOM   10851 H H    . PHE B 1 378 ? -25.135 37.100  52.190 1.00 18.93 ?  344  PHE B H    1 
ATOM   10852 H HA   . PHE B 1 378 ? -27.167 35.605  52.884 1.00 17.19 ?  344  PHE B HA   1 
ATOM   10853 H HB2  . PHE B 1 378 ? -24.621 35.915  54.082 1.00 18.72 ?  344  PHE B HB2  1 
ATOM   10854 H HB3  . PHE B 1 378 ? -25.692 34.891  54.657 1.00 18.72 ?  344  PHE B HB3  1 
ATOM   10855 H HD1  . PHE B 1 378 ? -26.462 33.069  53.080 1.00 22.02 ?  344  PHE B HD1  1 
ATOM   10856 H HD2  . PHE B 1 378 ? -23.158 35.192  52.421 1.00 24.11 ?  344  PHE B HD2  1 
ATOM   10857 H HE1  . PHE B 1 378 ? -25.730 31.469  51.557 1.00 21.60 ?  344  PHE B HE1  1 
ATOM   10858 H HE2  . PHE B 1 378 ? -22.421 33.567  50.931 1.00 29.14 ?  344  PHE B HE2  1 
ATOM   10859 H HZ   . PHE B 1 378 ? -23.732 31.740  50.493 1.00 23.16 ?  344  PHE B HZ   1 
ATOM   10860 N N    . ASP B 1 379 ? -28.111 36.385  55.079 1.00 15.52 ?  345  ASP B N    1 
ATOM   10861 C CA   . ASP B 1 379 ? -28.807 37.099  56.148 1.00 16.41 ?  345  ASP B CA   1 
ATOM   10862 C C    . ASP B 1 379 ? -27.856 37.534  57.249 1.00 15.18 ?  345  ASP B C    1 
ATOM   10863 O O    . ASP B 1 379 ? -28.042 38.577  57.886 1.00 16.30 ?  345  ASP B O    1 
ATOM   10864 C CB   . ASP B 1 379 ? -29.935 36.221  56.701 1.00 20.93 ?  345  ASP B CB   1 
ATOM   10865 C CG   . ASP B 1 379 ? -31.086 35.999  55.676 1.00 23.75 ?  345  ASP B CG   1 
ATOM   10866 O OD1  . ASP B 1 379 ? -31.151 36.740  54.681 1.00 27.96 ?  345  ASP B OD1  1 
ATOM   10867 O OD2  . ASP B 1 379 ? -31.921 35.103  55.909 1.00 31.46 ?  345  ASP B OD2  1 
ATOM   10868 H H    . ASP B 1 379 ? -28.368 35.574  54.954 1.00 18.62 ?  345  ASP B H    1 
ATOM   10869 H HA   . ASP B 1 379 ? -29.208 37.905  55.786 1.00 19.69 ?  345  ASP B HA   1 
ATOM   10870 H HB2  . ASP B 1 379 ? -29.573 35.353  56.938 1.00 25.11 ?  345  ASP B HB2  1 
ATOM   10871 H HB3  . ASP B 1 379 ? -30.312 36.649  57.486 1.00 25.11 ?  345  ASP B HB3  1 
ATOM   10872 N N    . GLN B 1 380 ? -26.804 36.755  57.461 1.00 15.07 ?  346  GLN B N    1 
ATOM   10873 C CA   . GLN B 1 380 ? -25.778 37.070  58.449 1.00 13.64 ?  346  GLN B CA   1 
ATOM   10874 C C    . GLN B 1 380 ? -25.060 38.372  58.145 1.00 15.94 ?  346  GLN B C    1 
ATOM   10875 O O    . GLN B 1 380 ? -24.343 38.891  59.014 1.00 18.72 ?  346  GLN B O    1 
ATOM   10876 C CB   . GLN B 1 380 ? -24.748 35.946  58.503 1.00 14.21 ?  346  GLN B CB   1 
ATOM   10877 C CG   . GLN B 1 380 ? -25.249 34.607  59.024 1.00 14.37 ?  346  GLN B CG   1 
ATOM   10878 C CD   . GLN B 1 380 ? -25.834 33.717  57.952 1.00 14.69 ?  346  GLN B CD   1 
ATOM   10879 O OE1  . GLN B 1 380 ? -26.304 34.198  56.914 1.00 15.42 ?  346  GLN B OE1  1 
ATOM   10880 N NE2  . GLN B 1 380 ? -25.818 32.430  58.189 1.00 14.67 ?  346  GLN B NE2  1 
ATOM   10881 H H    . GLN B 1 380 ? -26.655 36.022  57.037 1.00 18.09 ?  346  GLN B H    1 
ATOM   10882 H HA   . GLN B 1 380 ? -26.206 37.151  59.315 1.00 16.37 ?  346  GLN B HA   1 
ATOM   10883 H HB2  . GLN B 1 380 ? -24.414 35.797  57.605 1.00 17.05 ?  346  GLN B HB2  1 
ATOM   10884 H HB3  . GLN B 1 380 ? -24.024 36.226  59.084 1.00 17.05 ?  346  GLN B HB3  1 
ATOM   10885 H HG2  . GLN B 1 380 ? -24.507 34.132  59.429 1.00 17.25 ?  346  GLN B HG2  1 
ATOM   10886 H HG3  . GLN B 1 380 ? -25.941 34.768  59.684 1.00 17.25 ?  346  GLN B HG3  1 
ATOM   10887 H HE21 . GLN B 1 380 ? -25.485 32.132  58.924 1.00 17.61 ?  346  GLN B HE21 1 
ATOM   10888 H HE22 . GLN B 1 380 ? -26.139 31.882  57.609 1.00 17.61 ?  346  GLN B HE22 1 
ATOM   10889 N N    . TYR B 1 381 ? -25.125 38.871  56.914 1.00 14.40 ?  347  TYR B N    1 
ATOM   10890 C CA   . TYR B 1 381 ? -24.507 40.123  56.542 1.00 12.92 ?  347  TYR B CA   1 
ATOM   10891 C C    . TYR B 1 381 ? -25.382 41.335  56.847 1.00 15.95 ?  347  TYR B C    1 
ATOM   10892 O O    . TYR B 1 381 ? -24.891 42.482  56.790 1.00 15.75 ?  347  TYR B O    1 
ATOM   10893 C CB   . TYR B 1 381 ? -24.138 40.135  55.050 1.00 13.52 ?  347  TYR B CB   1 
ATOM   10894 C CG   . TYR B 1 381 ? -23.215 39.074  54.547 1.00 14.60 ?  347  TYR B CG   1 
ATOM   10895 C CD1  . TYR B 1 381 ? -22.530 38.201  55.396 1.00 16.30 ?  347  TYR B CD1  1 
ATOM   10896 C CD2  . TYR B 1 381 ? -23.002 38.936  53.182 1.00 15.42 ?  347  TYR B CD2  1 
ATOM   10897 C CE1  . TYR B 1 381 ? -21.683 37.246  54.870 1.00 17.68 ?  347  TYR B CE1  1 
ATOM   10898 C CE2  . TYR B 1 381 ? -22.161 37.950  52.671 1.00 18.37 ?  347  TYR B CE2  1 
ATOM   10899 C CZ   . TYR B 1 381 ? -21.521 37.116  53.519 1.00 20.79 ?  347  TYR B CZ   1 
ATOM   10900 O OH   . TYR B 1 381 ? -20.664 36.118  53.012 1.00 23.50 ?  347  TYR B OH   1 
ATOM   10901 H H    . TYR B 1 381 ? -25.534 38.487  56.263 1.00 17.28 ?  347  TYR B H    1 
ATOM   10902 H HA   . TYR B 1 381 ? -23.683 40.207  57.045 1.00 15.51 ?  347  TYR B HA   1 
ATOM   10903 H HB2  . TYR B 1 381 ? -24.960 40.052  54.542 1.00 16.23 ?  347  TYR B HB2  1 
ATOM   10904 H HB3  . TYR B 1 381 ? -23.714 40.986  54.858 1.00 16.23 ?  347  TYR B HB3  1 
ATOM   10905 H HD1  . TYR B 1 381 ? -22.644 38.264  56.317 1.00 19.56 ?  347  TYR B HD1  1 
ATOM   10906 H HD2  . TYR B 1 381 ? -23.432 39.515  52.595 1.00 18.50 ?  347  TYR B HD2  1 
ATOM   10907 H HE1  . TYR B 1 381 ? -21.216 36.683  55.444 1.00 21.21 ?  347  TYR B HE1  1 
ATOM   10908 H HE2  . TYR B 1 381 ? -22.041 37.867  51.752 1.00 22.05 ?  347  TYR B HE2  1 
ATOM   10909 H HH   . TYR B 1 381 ? -20.670 36.134  52.172 1.00 28.20 ?  347  TYR B HH   1 
ATOM   10910 N N    . LYS B 1 382 ? -26.659 41.101  57.133 1.00 15.19 ?  348  LYS B N    1 
ATOM   10911 C CA   . LYS B 1 382 ? -27.610 42.190  57.324 1.00 18.45 ?  348  LYS B CA   1 
ATOM   10912 C C    . LYS B 1 382 ? -27.929 42.427  58.792 1.00 17.65 ?  348  LYS B C    1 
ATOM   10913 O O    . LYS B 1 382 ? -28.379 43.527  59.147 1.00 19.01 ?  348  LYS B O    1 
ATOM   10914 C CB   . LYS B 1 382 ? -28.925 41.892  56.587 1.00 21.07 ?  348  LYS B CB   1 
ATOM   10915 C CG   . LYS B 1 382 ? -28.763 41.430  55.147 1.00 28.45 ?  348  LYS B CG   1 
ATOM   10916 C CD   . LYS B 1 382 ? -30.120 41.002  54.563 1.00 34.52 ?  348  LYS B CD   1 
ATOM   10917 C CE   . LYS B 1 382 ? -29.946 40.157  53.310 1.00 38.23 ?  348  LYS B CE   1 
ATOM   10918 N NZ   . LYS B 1 382 ? -31.215 39.492  52.928 1.00 42.92 ?  348  LYS B NZ   1 
ATOM   10919 H H    . LYS B 1 382 ? -27.000 40.317  57.222 1.00 18.23 ?  348  LYS B H    1 
ATOM   10920 H HA   . LYS B 1 382 ? -27.235 43.002  56.948 1.00 22.15 ?  348  LYS B HA   1 
ATOM   10921 H HB2  . LYS B 1 382 ? -29.395 41.192  57.066 1.00 25.28 ?  348  LYS B HB2  1 
ATOM   10922 H HB3  . LYS B 1 382 ? -29.460 42.701  56.574 1.00 25.28 ?  348  LYS B HB3  1 
ATOM   10923 H HG2  . LYS B 1 382 ? -28.411 42.156  54.610 1.00 34.14 ?  348  LYS B HG2  1 
ATOM   10924 H HG3  . LYS B 1 382 ? -28.160 40.671  55.116 1.00 34.14 ?  348  LYS B HG3  1 
ATOM   10925 H HD2  . LYS B 1 382 ? -30.602 40.476  55.220 1.00 41.42 ?  348  LYS B HD2  1 
ATOM   10926 H HD3  . LYS B 1 382 ? -30.633 41.791  54.329 1.00 41.42 ?  348  LYS B HD3  1 
ATOM   10927 H HE2  . LYS B 1 382 ? -29.665 40.725  52.576 1.00 45.88 ?  348  LYS B HE2  1 
ATOM   10928 H HE3  . LYS B 1 382 ? -29.279 39.472  53.474 1.00 45.88 ?  348  LYS B HE3  1 
ATOM   10929 H HZ1  . LYS B 1 382 ? -31.521 39.007  53.609 1.00 51.50 ?  348  LYS B HZ1  1 
ATOM   10930 H HZ2  . LYS B 1 382 ? -31.825 40.103  52.711 1.00 51.50 ?  348  LYS B HZ2  1 
ATOM   10931 H HZ3  . LYS B 1 382 ? -31.080 38.957  52.230 1.00 51.50 ?  348  LYS B HZ3  1 
ATOM   10932 N N    . LYS B 1 383 ? -27.704 41.435  59.636 1.00 16.38 ?  349  LYS B N    1 
ATOM   10933 C CA   . LYS B 1 383 ? -28.058 41.548  61.050 1.00 17.51 ?  349  LYS B CA   1 
ATOM   10934 C C    . LYS B 1 383 ? -27.090 42.460  61.796 1.00 18.81 ?  349  LYS B C    1 
ATOM   10935 O O    . LYS B 1 383 ? -25.911 42.597  61.451 1.00 17.55 ?  349  LYS B O    1 
ATOM   10936 C CB   . LYS B 1 383 ? -28.072 40.171  61.677 1.00 17.45 ?  349  LYS B CB   1 
ATOM   10937 C CG   . LYS B 1 383 ? -29.230 39.325  61.159 1.00 17.99 ?  349  LYS B CG   1 
ATOM   10938 C CD   . LYS B 1 383 ? -29.200 37.908  61.685 1.00 18.35 ?  349  LYS B CD   1 
ATOM   10939 C CE   . LYS B 1 383 ? -30.445 37.098  61.227 1.00 19.01 ?  349  LYS B CE   1 
ATOM   10940 N NZ   . LYS B 1 383 ? -30.490 35.705  61.776 1.00 21.57 ?  349  LYS B NZ   1 
ATOM   10941 H H    . LYS B 1 383 ? -27.347 40.683  59.421 1.00 19.66 ?  349  LYS B H    1 
ATOM   10942 H HA   . LYS B 1 383 ? -28.941 41.941  61.135 1.00 21.01 ?  349  LYS B HA   1 
ATOM   10943 H HB2  . LYS B 1 383 ? -27.243 39.714  61.465 1.00 20.94 ?  349  LYS B HB2  1 
ATOM   10944 H HB3  . LYS B 1 383 ? -28.166 40.258  62.639 1.00 20.94 ?  349  LYS B HB3  1 
ATOM   10945 H HG2  . LYS B 1 383 ? -30.066 39.730  61.436 1.00 21.59 ?  349  LYS B HG2  1 
ATOM   10946 H HG3  . LYS B 1 383 ? -29.184 39.286  60.191 1.00 21.59 ?  349  LYS B HG3  1 
ATOM   10947 H HD2  . LYS B 1 383 ? -28.407 37.459  61.354 1.00 22.02 ?  349  LYS B HD2  1 
ATOM   10948 H HD3  . LYS B 1 383 ? -29.191 37.926  62.655 1.00 22.02 ?  349  LYS B HD3  1 
ATOM   10949 H HE2  . LYS B 1 383 ? -31.245 37.559  61.523 1.00 22.81 ?  349  LYS B HE2  1 
ATOM   10950 H HE3  . LYS B 1 383 ? -30.438 37.035  60.259 1.00 22.81 ?  349  LYS B HE3  1 
ATOM   10951 H HZ1  . LYS B 1 383 ? -31.188 35.267  61.438 1.00 25.88 ?  349  LYS B HZ1  1 
ATOM   10952 H HZ2  . LYS B 1 383 ? -29.745 35.269  61.561 1.00 25.88 ?  349  LYS B HZ2  1 
ATOM   10953 H HZ3  . LYS B 1 383 ? -30.566 35.729  62.662 1.00 25.88 ?  349  LYS B HZ3  1 
ATOM   10954 N N    . ALA B 1 384 ? -27.601 43.101  62.848 1.00 17.70 ?  350  ALA B N    1 
ATOM   10955 C CA   . ALA B 1 384 ? -26.775 43.993  63.634 1.00 15.94 ?  350  ALA B CA   1 
ATOM   10956 C C    . ALA B 1 384 ? -25.672 43.196  64.303 1.00 16.79 ?  350  ALA B C    1 
ATOM   10957 O O    . ALA B 1 384 ? -25.914 42.146  64.912 1.00 17.80 ?  350  ALA B O    1 
ATOM   10958 C CB   . ALA B 1 384 ? -27.628 44.676  64.708 1.00 19.90 ?  350  ALA B CB   1 
ATOM   10959 H H    . ALA B 1 384 ? -28.414 43.033  63.119 1.00 21.24 ?  350  ALA B H    1 
ATOM   10960 H HA   . ALA B 1 384 ? -26.386 44.673  63.062 1.00 19.13 ?  350  ALA B HA   1 
ATOM   10961 H HB1  . ALA B 1 384 ? -27.085 45.333  65.173 1.00 23.88 ?  350  ALA B HB1  1 
ATOM   10962 H HB2  . ALA B 1 384 ? -28.383 45.113  64.282 1.00 23.88 ?  350  ALA B HB2  1 
ATOM   10963 H HB3  . ALA B 1 384 ? -27.944 44.006  65.334 1.00 23.88 ?  350  ALA B HB3  1 
ATOM   10964 N N    . LEU B 1 385 ? -24.448 43.693  64.149 1.00 17.05 ?  351  LEU B N    1 
ATOM   10965 C CA   . LEU B 1 385 ? -23.266 43.059  64.710 1.00 16.27 ?  351  LEU B CA   1 
ATOM   10966 C C    . LEU B 1 385 ? -22.799 43.853  65.923 1.00 15.69 ?  351  LEU B C    1 
ATOM   10967 O O    . LEU B 1 385 ? -22.900 43.360  67.064 1.00 19.25 ?  351  LEU B O    1 
ATOM   10968 C CB   . LEU B 1 385 ? -22.205 42.982  63.609 1.00 14.91 ?  351  LEU B CB   1 
ATOM   10969 C CG   . LEU B 1 385 ? -20.803 42.565  64.027 1.00 15.07 ?  351  LEU B CG   1 
ATOM   10970 C CD1  . LEU B 1 385 ? -20.760 41.201  64.663 1.00 16.75 ?  351  LEU B CD1  1 
ATOM   10971 C CD2  . LEU B 1 385 ? -19.875 42.568  62.807 1.00 15.28 ?  351  LEU B CD2  1 
ATOM   10972 H H    . LEU B 1 385 ? -24.276 44.414  63.712 1.00 20.46 ?  351  LEU B H    1 
ATOM   10973 H HA   . LEU B 1 385 ? -23.449 42.158  65.017 1.00 19.52 ?  351  LEU B HA   1 
ATOM   10974 H HB2  . LEU B 1 385 ? -22.506 42.338  62.949 1.00 17.89 ?  351  LEU B HB2  1 
ATOM   10975 H HB3  . LEU B 1 385 ? -22.130 43.861  63.205 1.00 17.89 ?  351  LEU B HB3  1 
ATOM   10976 H HG   . LEU B 1 385 ? -20.499 43.204  64.692 1.00 18.09 ?  351  LEU B HG   1 
ATOM   10977 H HD11 . LEU B 1 385 ? -19.867 41.040  65.007 1.00 20.10 ?  351  LEU B HD11 1 
ATOM   10978 H HD12 . LEU B 1 385 ? -21.404 41.169  65.387 1.00 20.10 ?  351  LEU B HD12 1 
ATOM   10979 H HD13 . LEU B 1 385 ? -20.981 40.534  63.994 1.00 20.10 ?  351  LEU B HD13 1 
ATOM   10980 H HD21 . LEU B 1 385 ? -18.977 42.337  63.091 1.00 18.33 ?  351  LEU B HD21 1 
ATOM   10981 H HD22 . LEU B 1 385 ? -20.197 41.916  62.164 1.00 18.33 ?  351  LEU B HD22 1 
ATOM   10982 H HD23 . LEU B 1 385 ? -19.879 43.453  62.409 1.00 18.33 ?  351  LEU B HD23 1 
ATOM   10983 N N    . GLY B 1 386 ? -22.336 45.077  65.717 1.00 16.66 ?  352  GLY B N    1 
ATOM   10984 C CA   . GLY B 1 386 ? -21.867 45.937  66.789 1.00 17.81 ?  352  GLY B CA   1 
ATOM   10985 C C    . GLY B 1 386 ? -20.409 45.691  67.145 1.00 18.63 ?  352  GLY B C    1 
ATOM   10986 O O    . GLY B 1 386 ? -19.779 44.726  66.712 1.00 16.99 ?  352  GLY B O    1 
ATOM   10987 H H    . GLY B 1 386 ? -22.283 45.443  64.941 1.00 19.99 ?  352  GLY B H    1 
ATOM   10988 H HA2  . GLY B 1 386 ? -21.962 46.864  66.520 1.00 21.37 ?  352  GLY B HA2  1 
ATOM   10989 H HA3  . GLY B 1 386 ? -22.404 45.782  67.582 1.00 21.37 ?  352  GLY B HA3  1 
ATOM   10990 N N    . ALA B 1 387 ? -19.850 46.623  67.905 1.00 18.72 ?  353  ALA B N    1 
ATOM   10991 C CA   . ALA B 1 387 ? -18.440 46.555  68.223 1.00 18.69 ?  353  ALA B CA   1 
ATOM   10992 C C    . ALA B 1 387 ? -18.130 45.395  69.175 1.00 17.04 ?  353  ALA B C    1 
ATOM   10993 O O    . ALA B 1 387 ? -18.962 45.006  70.005 1.00 18.03 ?  353  ALA B O    1 
ATOM   10994 C CB   . ALA B 1 387 ? -17.982 47.864  68.866 1.00 21.62 ?  353  ALA B CB   1 
ATOM   10995 H H    . ALA B 1 387 ? -20.264 47.297  68.244 1.00 22.47 ?  353  ALA B H    1 
ATOM   10996 H HA   . ALA B 1 387 ? -17.944 46.406  67.403 1.00 22.42 ?  353  ALA B HA   1 
ATOM   10997 H HB1  . ALA B 1 387 ? -17.033 47.805  69.060 1.00 25.94 ?  353  ALA B HB1  1 
ATOM   10998 H HB2  . ALA B 1 387 ? -18.148 48.594  68.249 1.00 25.94 ?  353  ALA B HB2  1 
ATOM   10999 H HB3  . ALA B 1 387 ? -18.479 48.004  69.687 1.00 25.94 ?  353  ALA B HB3  1 
ATOM   11000 N N    . PRO B 1 388 ? -16.929 44.827  69.088 1.00 17.69 ?  354  PRO B N    1 
ATOM   11001 C CA   . PRO B 1 388 ? -16.531 43.802  70.057 1.00 17.56 ?  354  PRO B CA   1 
ATOM   11002 C C    . PRO B 1 388 ? -16.498 44.401  71.452 1.00 20.14 ?  354  PRO B C    1 
ATOM   11003 O O    . PRO B 1 388 ? -16.089 45.549  71.648 1.00 23.82 ?  354  PRO B O    1 
ATOM   11004 C CB   . PRO B 1 388 ? -15.120 43.390  69.598 1.00 25.06 ?  354  PRO B CB   1 
ATOM   11005 C CG   . PRO B 1 388 ? -14.658 44.463  68.647 1.00 21.62 ?  354  PRO B CG   1 
ATOM   11006 C CD   . PRO B 1 388 ? -15.883 45.119  68.098 1.00 21.56 ?  354  PRO B CD   1 
ATOM   11007 H HA   . PRO B 1 388 ? -17.119 43.031  70.020 1.00 21.07 ?  354  PRO B HA   1 
ATOM   11008 H HB2  . PRO B 1 388 ? -14.531 43.336  70.367 1.00 30.08 ?  354  PRO B HB2  1 
ATOM   11009 H HB3  . PRO B 1 388 ? -15.161 42.530  69.151 1.00 30.08 ?  354  PRO B HB3  1 
ATOM   11010 H HG2  . PRO B 1 388 ? -14.115 45.107  69.128 1.00 25.95 ?  354  PRO B HG2  1 
ATOM   11011 H HG3  . PRO B 1 388 ? -14.140 44.060  67.933 1.00 25.95 ?  354  PRO B HG3  1 
ATOM   11012 H HD2  . PRO B 1 388 ? -15.749 46.076  68.015 1.00 25.87 ?  354  PRO B HD2  1 
ATOM   11013 H HD3  . PRO B 1 388 ? -16.115 44.740  67.235 1.00 25.87 ?  354  PRO B HD3  1 
ATOM   11014 N N    . LEU B 1 389 ? -16.949 43.615  72.423 1.00 21.29 ?  355  LEU B N    1 
ATOM   11015 C CA   . LEU B 1 389 ? -16.805 44.010  73.826 1.00 25.63 ?  355  LEU B CA   1 
ATOM   11016 C C    . LEU B 1 389 ? -15.623 43.337  74.513 1.00 34.26 ?  355  LEU B C    1 
ATOM   11017 O O    . LEU B 1 389 ? -15.403 43.581  75.699 1.00 29.15 ?  355  LEU B O    1 
ATOM   11018 C CB   . LEU B 1 389 ? -18.128 43.884  74.605 1.00 35.25 ?  355  LEU B CB   1 
ATOM   11019 C CG   . LEU B 1 389 ? -19.411 44.185  73.813 1.00 35.98 ?  355  LEU B CG   1 
ATOM   11020 C CD1  . LEU B 1 389 ? -20.690 43.647  74.429 1.00 41.58 ?  355  LEU B CD1  1 
ATOM   11021 C CD2  . LEU B 1 389 ? -19.544 45.679  73.661 1.00 41.86 ?  355  LEU B CD2  1 
ATOM   11022 H H    . LEU B 1 389 ? -17.337 42.857  72.299 1.00 25.54 ?  355  LEU B H    1 
ATOM   11023 H HA   . LEU B 1 389 ? -16.620 44.962  73.863 1.00 30.76 ?  355  LEU B HA   1 
ATOM   11024 H HB2  . LEU B 1 389 ? -18.200 42.974  74.932 1.00 42.31 ?  355  LEU B HB2  1 
ATOM   11025 H HB3  . LEU B 1 389 ? -18.099 44.503  75.351 1.00 42.31 ?  355  LEU B HB3  1 
ATOM   11026 H HG   . LEU B 1 389 ? -19.321 43.733  72.960 1.00 43.18 ?  355  LEU B HG   1 
ATOM   11027 H HD11 . LEU B 1 389 ? -21.438 43.878  73.857 1.00 49.89 ?  355  LEU B HD11 1 
ATOM   11028 H HD12 . LEU B 1 389 ? -20.620 42.683  74.509 1.00 49.89 ?  355  LEU B HD12 1 
ATOM   11029 H HD13 . LEU B 1 389 ? -20.809 44.044  75.306 1.00 49.89 ?  355  LEU B HD13 1 
ATOM   11030 H HD21 . LEU B 1 389 ? -20.366 45.876  73.184 1.00 50.23 ?  355  LEU B HD21 1 
ATOM   11031 H HD22 . LEU B 1 389 ? -19.568 46.085  74.542 1.00 50.23 ?  355  LEU B HD22 1 
ATOM   11032 H HD23 . LEU B 1 389 ? -18.783 46.015  73.162 1.00 50.23 ?  355  LEU B HD23 1 
ATOM   11033 N N    . GLY B 1 390 ? -14.818 42.574  73.776 1.00 28.35 ?  356  GLY B N    1 
ATOM   11034 C CA   . GLY B 1 390 ? -13.534 42.073  74.262 1.00 25.60 ?  356  GLY B CA   1 
ATOM   11035 C C    . GLY B 1 390 ? -12.900 41.204  73.197 1.00 33.28 ?  356  GLY B C    1 
ATOM   11036 O O    . GLY B 1 390 ? -13.544 40.823  72.215 1.00 27.47 ?  356  GLY B O    1 
ATOM   11037 H H    . GLY B 1 390 ? -14.995 42.325  72.972 1.00 34.02 ?  356  GLY B H    1 
ATOM   11038 H HA2  . GLY B 1 390 ? -12.941 42.814  74.462 1.00 30.72 ?  356  GLY B HA2  1 
ATOM   11039 H HA3  . GLY B 1 390 ? -13.664 41.547  75.066 1.00 30.72 ?  356  GLY B HA3  1 
ATOM   11040 N N    . LYS B 1 391 ? -11.613 40.910  73.387 1.00 27.40 ?  357  LYS B N    1 
ATOM   11041 C CA   . LYS B 1 391 ? -10.944 39.995  72.479 1.00 23.04 ?  357  LYS B CA   1 
ATOM   11042 C C    . LYS B 1 391 ? -11.541 38.597  72.625 1.00 21.12 ?  357  LYS B C    1 
ATOM   11043 O O    . LYS B 1 391 ? -12.230 38.284  73.598 1.00 23.21 ?  357  LYS B O    1 
ATOM   11044 C CB   . LYS B 1 391 ? -9.427  39.985  72.697 1.00 35.74 ?  357  LYS B CB   1 
ATOM   11045 C CG   . LYS B 1 391 ? -8.723  41.346  72.384 1.00 34.80 ?  357  LYS B CG   1 
ATOM   11046 C CD   . LYS B 1 391 ? -9.099  42.021  71.003 1.00 22.90 ?  357  LYS B CD   1 
ATOM   11047 C CE   . LYS B 1 391 ? -8.499  43.424  70.893 1.00 48.00 ?  357  LYS B CE   1 
ATOM   11048 N NZ   . LYS B 1 391 ? -7.465  43.703  71.954 1.00 41.64 ?  357  LYS B NZ   1 
ATOM   11049 H H    . LYS B 1 391 ? -11.121 41.223  74.019 1.00 32.88 ?  357  LYS B H    1 
ATOM   11050 H HA   . LYS B 1 391 ? -11.077 40.287  71.563 1.00 27.65 ?  357  LYS B HA   1 
ATOM   11051 H HB2  . LYS B 1 391 ? -9.249  39.769  73.626 1.00 42.89 ?  357  LYS B HB2  1 
ATOM   11052 H HB3  . LYS B 1 391 ? -9.035  39.312  72.119 1.00 42.89 ?  357  LYS B HB3  1 
ATOM   11053 H HG2  . LYS B 1 391 ? -8.957  41.976  73.083 1.00 41.76 ?  357  LYS B HG2  1 
ATOM   11054 H HG3  . LYS B 1 391 ? -7.764  41.198  72.378 1.00 41.76 ?  357  LYS B HG3  1 
ATOM   11055 H HD2  . LYS B 1 391 ? -8.753  41.481  70.275 1.00 27.48 ?  357  LYS B HD2  1 
ATOM   11056 H HD3  . LYS B 1 391 ? -10.064 42.094  70.932 1.00 27.48 ?  357  LYS B HD3  1 
ATOM   11057 H HE2  . LYS B 1 391 ? -8.072  43.519  70.027 1.00 57.60 ?  357  LYS B HE2  1 
ATOM   11058 H HE3  . LYS B 1 391 ? -9.208  44.080  70.987 1.00 57.60 ?  357  LYS B HE3  1 
ATOM   11059 H HZ1  . LYS B 1 391 ? -7.086  44.495  71.810 1.00 49.97 ?  357  LYS B HZ1  1 
ATOM   11060 H HZ2  . LYS B 1 391 ? -7.847  43.707  72.758 1.00 49.97 ?  357  LYS B HZ2  1 
ATOM   11061 H HZ3  . LYS B 1 391 ? -6.834  43.074  71.937 1.00 49.97 ?  357  LYS B HZ3  1 
ATOM   11062 N N    . ALA B 1 392 ? -11.334 37.787  71.608 1.00 20.11 ?  358  ALA B N    1 
ATOM   11063 C CA   . ALA B 1 392 ? -11.762 36.407  71.679 1.00 17.34 ?  358  ALA B CA   1 
ATOM   11064 C C    . ALA B 1 392 ? -11.051 35.705  72.827 1.00 19.33 ?  358  ALA B C    1 
ATOM   11065 O O    . ALA B 1 392 ? -9.912  36.033  73.167 1.00 21.90 ?  358  ALA B O    1 
ATOM   11066 C CB   . ALA B 1 392 ? -11.452 35.704  70.364 1.00 20.91 ?  358  ALA B CB   1 
ATOM   11067 H H    . ALA B 1 392 ? -10.950 38.009  70.871 1.00 24.13 ?  358  ALA B H    1 
ATOM   11068 H HA   . ALA B 1 392 ? -12.719 36.359  71.832 1.00 20.81 ?  358  ALA B HA   1 
ATOM   11069 H HB1  . ALA B 1 392 ? -11.714 34.773  70.434 1.00 25.10 ?  358  ALA B HB1  1 
ATOM   11070 H HB2  . ALA B 1 392 ? -11.949 36.135  69.651 1.00 25.10 ?  358  ALA B HB2  1 
ATOM   11071 H HB3  . ALA B 1 392 ? -10.500 35.768  70.189 1.00 25.10 ?  358  ALA B HB3  1 
ATOM   11072 N N    . ILE B 1 393 ? -11.750 34.756  73.443 1.00 18.33 ?  359  ILE B N    1 
ATOM   11073 C CA   . ILE B 1 393 ? -11.184 33.906  74.481 1.00 20.59 ?  359  ILE B CA   1 
ATOM   11074 C C    . ILE B 1 393 ? -11.069 32.501  73.920 1.00 17.83 ?  359  ILE B C    1 
ATOM   11075 O O    . ILE B 1 393 ? -12.046 31.938  73.411 1.00 17.93 ?  359  ILE B O    1 
ATOM   11076 C CB   . ILE B 1 393 ? -12.048 33.901  75.751 1.00 23.03 ?  359  ILE B CB   1 
ATOM   11077 C CG1  . ILE B 1 393 ? -12.102 35.293  76.380 1.00 28.88 ?  359  ILE B CG1  1 
ATOM   11078 C CG2  . ILE B 1 393 ? -11.475 32.897  76.751 1.00 29.09 ?  359  ILE B CG2  1 
ATOM   11079 C CD1  . ILE B 1 393 ? -13.278 35.490  77.332 1.00 32.34 ?  359  ILE B CD1  1 
ATOM   11080 H H    . ILE B 1 393 ? -12.575 34.584  73.272 1.00 21.99 ?  359  ILE B H    1 
ATOM   11081 H HA   . ILE B 1 393 ? -10.301 34.233  74.712 1.00 24.70 ?  359  ILE B HA   1 
ATOM   11082 H HB   . ILE B 1 393 ? -12.952 33.644  75.509 1.00 27.64 ?  359  ILE B HB   1 
ATOM   11083 H HG12 . ILE B 1 393 ? -11.285 35.440  76.882 1.00 34.65 ?  359  ILE B HG12 1 
ATOM   11084 H HG13 . ILE B 1 393 ? -12.179 35.953  75.672 1.00 34.65 ?  359  ILE B HG13 1 
ATOM   11085 H HG21 . ILE B 1 393 ? -11.832 33.089  77.632 1.00 34.91 ?  359  ILE B HG21 1 
ATOM   11086 H HG22 . ILE B 1 393 ? -11.729 32.001  76.480 1.00 34.91 ?  359  ILE B HG22 1 
ATOM   11087 H HG23 . ILE B 1 393 ? -10.508 32.978  76.761 1.00 34.91 ?  359  ILE B HG23 1 
ATOM   11088 H HD11 . ILE B 1 393 ? -13.290 36.413  77.633 1.00 38.81 ?  359  ILE B HD11 1 
ATOM   11089 H HD12 . ILE B 1 393 ? -14.102 35.284  76.864 1.00 38.81 ?  359  ILE B HD12 1 
ATOM   11090 H HD13 . ILE B 1 393 ? -13.172 34.896  78.092 1.00 38.81 ?  359  ILE B HD13 1 
ATOM   11091 N N    . LYS B 1 394 ? -9.894  31.915  74.034 1.00 18.99 ?  360  LYS B N    1 
ATOM   11092 C CA   . LYS B 1 394 ? -9.604  30.580  73.557 1.00 15.74 ?  360  LYS B CA   1 
ATOM   11093 C C    . LYS B 1 394 ? -9.578  29.587  74.712 1.00 21.02 ?  360  LYS B C    1 
ATOM   11094 O O    . LYS B 1 394 ? -8.758  29.727  75.632 1.00 22.08 ?  360  LYS B O    1 
ATOM   11095 C CB   . LYS B 1 394 ? -8.263  30.599  72.823 1.00 22.44 ?  360  LYS B CB   1 
ATOM   11096 C CG   . LYS B 1 394 ? -7.836  29.281  72.292 1.00 19.09 ?  360  LYS B CG   1 
ATOM   11097 C CD   . LYS B 1 394 ? -6.429  29.371  71.687 1.00 27.00 ?  360  LYS B CD   1 
ATOM   11098 C CE   . LYS B 1 394 ? -5.988  28.089  71.020 1.00 21.00 ?  360  LYS B CE   1 
ATOM   11099 N NZ   . LYS B 1 394 ? -5.898  26.908  71.955 1.00 21.57 ?  360  LYS B NZ   1 
ATOM   11100 H H    . LYS B 1 394 ? -9.214  32.290  74.403 1.00 22.79 ?  360  LYS B H    1 
ATOM   11101 H HA   . LYS B 1 394 ? -10.307 30.284  72.958 1.00 18.89 ?  360  LYS B HA   1 
ATOM   11102 H HB2  . LYS B 1 394 ? -8.329  31.210  72.073 1.00 26.93 ?  360  LYS B HB2  1 
ATOM   11103 H HB3  . LYS B 1 394 ? -7.578  30.903  73.439 1.00 26.93 ?  360  LYS B HB3  1 
ATOM   11104 H HG2  . LYS B 1 394 ? -7.821  28.630  73.011 1.00 22.91 ?  360  LYS B HG2  1 
ATOM   11105 H HG3  . LYS B 1 394 ? -8.452  28.995  71.599 1.00 22.91 ?  360  LYS B HG3  1 
ATOM   11106 H HD2  . LYS B 1 394 ? -6.418  30.074  71.018 1.00 32.40 ?  360  LYS B HD2  1 
ATOM   11107 H HD3  . LYS B 1 394 ? -5.795  29.574  72.392 1.00 32.40 ?  360  LYS B HD3  1 
ATOM   11108 H HE2  . LYS B 1 394 ? -6.626  27.865  70.324 1.00 25.20 ?  360  LYS B HE2  1 
ATOM   11109 H HE3  . LYS B 1 394 ? -5.109  28.226  70.633 1.00 25.20 ?  360  LYS B HE3  1 
ATOM   11110 H HZ1  . LYS B 1 394 ? -5.650  26.181  71.505 1.00 25.88 ?  360  LYS B HZ1  1 
ATOM   11111 H HZ2  . LYS B 1 394 ? -5.300  27.070  72.594 1.00 25.88 ?  360  LYS B HZ2  1 
ATOM   11112 H HZ3  . LYS B 1 394 ? -6.690  26.758  72.333 1.00 25.88 ?  360  LYS B HZ3  1 
ATOM   11113 N N    . ASN B 1 395 ? -10.436 28.576  74.655 1.00 17.68 ?  361  ASN B N    1 
ATOM   11114 C CA   . ASN B 1 395 ? -10.458 27.484  75.650 1.00 19.12 ?  361  ASN B CA   1 
ATOM   11115 C C    . ASN B 1 395 ? -10.349 26.183  74.855 1.00 16.39 ?  361  ASN B C    1 
ATOM   11116 O O    . ASN B 1 395 ? -11.318 25.597  74.387 1.00 17.79 ?  361  ASN B O    1 
ATOM   11117 C CB   . ASN B 1 395 ? -11.705 27.564  76.482 1.00 23.37 ?  361  ASN B CB   1 
ATOM   11118 C CG   . ASN B 1 395 ? -11.786 28.839  77.282 1.00 26.05 ?  361  ASN B CG   1 
ATOM   11119 O OD1  . ASN B 1 395 ? -12.758 29.607  77.152 1.00 32.42 ?  361  ASN B OD1  1 
ATOM   11120 N ND2  . ASN B 1 395 ? -10.775 29.099  78.092 1.00 27.90 ?  361  ASN B ND2  1 
ATOM   11121 H H    . ASN B 1 395 ? -11.031 28.490  74.040 1.00 21.22 ?  361  ASN B H    1 
ATOM   11122 H HA   . ASN B 1 395 ? -9.699  27.539  76.251 1.00 22.95 ?  361  ASN B HA   1 
ATOM   11123 H HB2  . ASN B 1 395 ? -12.478 27.527  75.897 1.00 28.05 ?  361  ASN B HB2  1 
ATOM   11124 H HB3  . ASN B 1 395 ? -11.721 26.818  77.102 1.00 28.05 ?  361  ASN B HB3  1 
ATOM   11125 H HD21 . ASN B 1 395 ? -10.113 28.553  78.143 1.00 33.48 ?  361  ASN B HD21 1 
ATOM   11126 H HD22 . ASN B 1 395 ? -10.778 29.816  78.568 1.00 33.48 ?  361  ASN B HD22 1 
ATOM   11127 N N    . GLY B 1 396 ? -9.114  25.717  74.697 1.00 18.61 ?  362  GLY B N    1 
ATOM   11128 C CA   . GLY B 1 396 ? -8.876  24.581  73.840 1.00 17.02 ?  362  GLY B CA   1 
ATOM   11129 C C    . GLY B 1 396 ? -9.062  25.003  72.390 1.00 14.80 ?  362  GLY B C    1 
ATOM   11130 O O    . GLY B 1 396 ? -8.483  25.999  71.945 1.00 17.53 ?  362  GLY B O    1 
ATOM   11131 H H    . GLY B 1 396 ? -8.411  26.041  75.072 1.00 22.33 ?  362  GLY B H    1 
ATOM   11132 H HA2  . GLY B 1 396 ? -7.971  24.253  73.963 1.00 20.43 ?  362  GLY B HA2  1 
ATOM   11133 H HA3  . GLY B 1 396 ? -9.501  23.869  74.047 1.00 20.43 ?  362  GLY B HA3  1 
ATOM   11134 N N    . TYR B 1 397 ? -9.919  24.271  71.663 1.00 16.59 ?  363  TYR B N    1 
ATOM   11135 C CA   . TYR B 1 397 ? -10.258 24.598  70.280 1.00 15.83 ?  363  TYR B CA   1 
ATOM   11136 C C    . TYR B 1 397 ? -11.595 25.297  70.185 1.00 15.29 ?  363  TYR B C    1 
ATOM   11137 O O    . TYR B 1 397 ? -12.117 25.474  69.063 1.00 16.39 ?  363  TYR B O    1 
ATOM   11138 C CB   . TYR B 1 397 ? -10.312 23.328  69.458 1.00 15.16 ?  363  TYR B CB   1 
ATOM   11139 C CG   . TYR B 1 397 ? -8.970  22.645  69.220 1.00 17.42 ?  363  TYR B CG   1 
ATOM   11140 C CD1  . TYR B 1 397 ? -7.881  23.362  68.793 1.00 18.66 ?  363  TYR B CD1  1 
ATOM   11141 C CD2  . TYR B 1 397 ? -8.827  21.271  69.403 1.00 27.18 ?  363  TYR B CD2  1 
ATOM   11142 C CE1  . TYR B 1 397 ? -6.646  22.752  68.579 1.00 25.64 ?  363  TYR B CE1  1 
ATOM   11143 C CE2  . TYR B 1 397 ? -7.620  20.637  69.180 1.00 33.95 ?  363  TYR B CE2  1 
ATOM   11144 C CZ   . TYR B 1 397 ? -6.536  21.375  68.763 1.00 30.97 ?  363  TYR B CZ   1 
ATOM   11145 O OH   . TYR B 1 397 ? -5.334  20.716  68.552 1.00 38.07 ?  363  TYR B OH   1 
ATOM   11146 H H    . TYR B 1 397 ? -10.320 23.570  71.958 1.00 19.91 ?  363  TYR B H    1 
ATOM   11147 H HA   . TYR B 1 397 ? -9.572  25.178  69.914 1.00 19.00 ?  363  TYR B HA   1 
ATOM   11148 H HB2  . TYR B 1 397 ? -10.883 22.692  69.916 1.00 18.19 ?  363  TYR B HB2  1 
ATOM   11149 H HB3  . TYR B 1 397 ? -10.685 23.542  68.588 1.00 18.19 ?  363  TYR B HB3  1 
ATOM   11150 H HD1  . TYR B 1 397 ? -7.969  24.276  68.643 1.00 22.39 ?  363  TYR B HD1  1 
ATOM   11151 H HD2  . TYR B 1 397 ? -9.560  20.770  69.681 1.00 32.62 ?  363  TYR B HD2  1 
ATOM   11152 H HE1  . TYR B 1 397 ? -5.909  23.254  68.318 1.00 30.77 ?  363  TYR B HE1  1 
ATOM   11153 H HE2  . TYR B 1 397 ? -7.540  19.720  69.310 1.00 40.74 ?  363  TYR B HE2  1 
ATOM   11154 H HH   . TYR B 1 397 ? -5.432  19.892  68.683 1.00 45.69 ?  363  TYR B HH   1 
ATOM   11155 N N    . ILE B 1 398 ? -12.164 25.715  71.321 1.00 14.96 ?  364  ILE B N    1 
ATOM   11156 C CA   . ILE B 1 398 ? -13.423 26.456  71.373 1.00 14.45 ?  364  ILE B CA   1 
ATOM   11157 C C    . ILE B 1 398 ? -13.105 27.892  71.704 1.00 16.23 ?  364  ILE B C    1 
ATOM   11158 O O    . ILE B 1 398 ? -12.431 28.184  72.700 1.00 16.61 ?  364  ILE B O    1 
ATOM   11159 C CB   . ILE B 1 398 ? -14.394 25.826  72.387 1.00 15.36 ?  364  ILE B CB   1 
ATOM   11160 C CG1  . ILE B 1 398 ? -14.777 24.449  71.917 1.00 17.17 ?  364  ILE B CG1  1 
ATOM   11161 C CG2  . ILE B 1 398 ? -15.615 26.719  72.511 1.00 21.73 ?  364  ILE B CG2  1 
ATOM   11162 C CD1  . ILE B 1 398 ? -15.554 23.592  72.943 1.00 20.07 ?  364  ILE B CD1  1 
ATOM   11163 H H    . ILE B 1 398 ? -11.825 25.575  72.099 1.00 17.96 ?  364  ILE B H    1 
ATOM   11164 H HA   . ILE B 1 398 ? -13.852 26.448  70.503 1.00 17.34 ?  364  ILE B HA   1 
ATOM   11165 H HB   . ILE B 1 398 ? -13.972 25.745  73.257 1.00 18.44 ?  364  ILE B HB   1 
ATOM   11166 H HG12 . ILE B 1 398 ? -15.339 24.539  71.132 1.00 20.61 ?  364  ILE B HG12 1 
ATOM   11167 H HG13 . ILE B 1 398 ? -13.967 23.966  71.692 1.00 20.61 ?  364  ILE B HG13 1 
ATOM   11168 H HG21 . ILE B 1 398 ? -16.318 26.232  72.970 1.00 26.08 ?  364  ILE B HG21 1 
ATOM   11169 H HG22 . ILE B 1 398 ? -15.377 27.511  73.018 1.00 26.08 ?  364  ILE B HG22 1 
ATOM   11170 H HG23 . ILE B 1 398 ? -15.913 26.972  71.623 1.00 26.08 ?  364  ILE B HG23 1 
ATOM   11171 H HD11 . ILE B 1 398 ? -15.711 22.713  72.566 1.00 24.08 ?  364  ILE B HD11 1 
ATOM   11172 H HD12 . ILE B 1 398 ? -15.026 23.514  73.754 1.00 24.08 ?  364  ILE B HD12 1 
ATOM   11173 H HD13 . ILE B 1 398 ? -16.399 24.024  73.140 1.00 24.08 ?  364  ILE B HD13 1 
ATOM   11174 N N    . TYR B 1 399 ? -13.536 28.813  70.854 1.00 14.65 ?  365  TYR B N    1 
ATOM   11175 C CA   . TYR B 1 399 ? -13.349 30.230  71.057 1.00 16.07 ?  365  TYR B CA   1 
ATOM   11176 C C    . TYR B 1 399 ? -14.701 30.883  71.281 1.00 14.75 ?  365  TYR B C    1 
ATOM   11177 O O    . TYR B 1 399 ? -15.705 30.508  70.659 1.00 16.37 ?  365  TYR B O    1 
ATOM   11178 C CB   . TYR B 1 399 ? -12.682 30.901  69.830 1.00 15.97 ?  365  TYR B CB   1 
ATOM   11179 C CG   . TYR B 1 399 ? -11.288 30.431  69.441 1.00 15.58 ?  365  TYR B CG   1 
ATOM   11180 C CD1  . TYR B 1 399 ? -11.106 29.190  68.881 1.00 15.93 ?  365  TYR B CD1  1 
ATOM   11181 C CD2  . TYR B 1 399 ? -10.171 31.260  69.559 1.00 19.23 ?  365  TYR B CD2  1 
ATOM   11182 C CE1  . TYR B 1 399 ? -9.882  28.744  68.456 1.00 23.35 ?  365  TYR B CE1  1 
ATOM   11183 C CE2  . TYR B 1 399 ? -8.914  30.796  69.163 1.00 16.95 ?  365  TYR B CE2  1 
ATOM   11184 C CZ   . TYR B 1 399 ? -8.800  29.564  68.592 1.00 19.66 ?  365  TYR B CZ   1 
ATOM   11185 O OH   . TYR B 1 399 ? -7.538  29.145  68.163 1.00 22.96 ?  365  TYR B OH   1 
ATOM   11186 H H    . TYR B 1 399 ? -13.956 28.628  70.127 1.00 17.58 ?  365  TYR B H    1 
ATOM   11187 H HA   . TYR B 1 399 ? -12.780 30.366  71.830 1.00 19.28 ?  365  TYR B HA   1 
ATOM   11188 H HB2  . TYR B 1 399 ? -13.254 30.749  69.061 1.00 19.16 ?  365  TYR B HB2  1 
ATOM   11189 H HB3  . TYR B 1 399 ? -12.616 31.852  70.011 1.00 19.16 ?  365  TYR B HB3  1 
ATOM   11190 H HD1  . TYR B 1 399 ? -11.842 28.630  68.787 1.00 19.12 ?  365  TYR B HD1  1 
ATOM   11191 H HD2  . TYR B 1 399 ? -10.264 32.120  69.901 1.00 23.08 ?  365  TYR B HD2  1 
ATOM   11192 H HE1  . TYR B 1 399 ? -9.790  27.898  68.081 1.00 28.02 ?  365  TYR B HE1  1 
ATOM   11193 H HE2  . TYR B 1 399 ? -8.160  31.324  69.288 1.00 20.34 ?  365  TYR B HE2  1 
ATOM   11194 H HH   . TYR B 1 399 ? -7.617  28.569  67.557 1.00 27.55 ?  365  TYR B HH   1 
ATOM   11195 N N    . THR B 1 400 ? -14.768 31.901  72.134 1.00 16.19 ?  366  THR B N    1 
ATOM   11196 C CA   . THR B 1 400 ? -15.940 32.742  72.253 1.00 18.20 ?  366  THR B CA   1 
ATOM   11197 C C    . THR B 1 400 ? -15.568 34.199  72.086 1.00 16.03 ?  366  THR B C    1 
ATOM   11198 O O    . THR B 1 400 ? -14.437 34.611  72.379 1.00 17.31 ?  366  THR B O    1 
ATOM   11199 C CB   . THR B 1 400 ? -16.646 32.583  73.631 1.00 19.21 ?  366  THR B CB   1 
ATOM   11200 O OG1  . THR B 1 400 ? -15.754 33.002  74.666 1.00 24.92 ?  366  THR B OG1  1 
ATOM   11201 C CG2  . THR B 1 400 ? -17.069 31.142  73.886 1.00 21.94 ?  366  THR B CG2  1 
ATOM   11202 H H    . THR B 1 400 ? -14.128 32.125  72.664 1.00 19.42 ?  366  THR B H    1 
ATOM   11203 H HA   . THR B 1 400 ? -16.556 32.489  71.548 1.00 21.85 ?  366  THR B HA   1 
ATOM   11204 H HB   . THR B 1 400 ? -17.449 33.127  73.638 1.00 23.05 ?  366  THR B HB   1 
ATOM   11205 H HG1  . THR B 1 400 ? -16.149 32.990  75.407 1.00 29.91 ?  366  THR B HG1  1 
ATOM   11206 H HG21 . THR B 1 400 ? -17.455 31.061  74.772 1.00 26.33 ?  366  THR B HG21 1 
ATOM   11207 H HG22 . THR B 1 400 ? -17.727 30.868  73.229 1.00 26.33 ?  366  THR B HG22 1 
ATOM   11208 H HG23 . THR B 1 400 ? -16.299 30.554  73.824 1.00 26.33 ?  366  THR B HG23 1 
ATOM   11209 N N    . ARG B 1 401 ? -16.504 34.994  71.602 1.00 15.68 ?  367  ARG B N    1 
ATOM   11210 C CA   . ARG B 1 401 ? -16.323 36.433  71.598 1.00 16.79 ?  367  ARG B CA   1 
ATOM   11211 C C    . ARG B 1 401 ? -17.676 37.136  71.641 1.00 16.74 ?  367  ARG B C    1 
ATOM   11212 O O    . ARG B 1 401 ? -18.642 36.680  71.009 1.00 20.98 ?  367  ARG B O    1 
ATOM   11213 C CB   . ARG B 1 401 ? -15.548 36.871  70.338 1.00 15.38 ?  367  ARG B CB   1 
ATOM   11214 C CG   . ARG B 1 401 ? -15.006 38.262  70.456 1.00 16.49 ?  367  ARG B CG   1 
ATOM   11215 C CD   . ARG B 1 401 ? -14.113 38.629  69.298 1.00 14.90 ?  367  ARG B CD   1 
ATOM   11216 N NE   . ARG B 1 401 ? -13.476 39.918  69.504 1.00 17.09 ?  367  ARG B NE   1 
ATOM   11217 C CZ   . ARG B 1 401 ? -12.735 40.523  68.592 1.00 17.85 ?  367  ARG B CZ   1 
ATOM   11218 N NH1  . ARG B 1 401 ? -12.585 40.022  67.385 1.00 16.35 ?  367  ARG B NH1  1 
ATOM   11219 N NH2  . ARG B 1 401 ? -12.152 41.679  68.889 1.00 17.01 ?  367  ARG B NH2  1 
ATOM   11220 H H    . ARG B 1 401 ? -17.252 34.725  71.272 1.00 18.82 ?  367  ARG B H    1 
ATOM   11221 H HA   . ARG B 1 401 ? -15.834 36.698  72.393 1.00 20.15 ?  367  ARG B HA   1 
ATOM   11222 H HB2  . ARG B 1 401 ? -14.802 36.267  70.199 1.00 18.45 ?  367  ARG B HB2  1 
ATOM   11223 H HB3  . ARG B 1 401 ? -16.144 36.843  69.573 1.00 18.45 ?  367  ARG B HB3  1 
ATOM   11224 H HG2  . ARG B 1 401 ? -15.744 38.890  70.478 1.00 19.79 ?  367  ARG B HG2  1 
ATOM   11225 H HG3  . ARG B 1 401 ? -14.485 38.332  71.271 1.00 19.79 ?  367  ARG B HG3  1 
ATOM   11226 H HD2  . ARG B 1 401 ? -13.420 37.958  69.201 1.00 17.88 ?  367  ARG B HD2  1 
ATOM   11227 H HD3  . ARG B 1 401 ? -14.644 38.678  68.487 1.00 17.88 ?  367  ARG B HD3  1 
ATOM   11228 H HE   . ARG B 1 401 ? -13.586 40.309  70.262 1.00 20.51 ?  367  ARG B HE   1 
ATOM   11229 H HH11 . ARG B 1 401 ? -12.973 39.284  67.174 1.00 19.62 ?  367  ARG B HH11 1 
ATOM   11230 H HH12 . ARG B 1 401 ? -12.099 40.433  66.807 1.00 19.62 ?  367  ARG B HH12 1 
ATOM   11231 H HH21 . ARG B 1 401 ? -12.258 42.026  69.669 1.00 20.41 ?  367  ARG B HH21 1 
ATOM   11232 H HH22 . ARG B 1 401 ? -11.669 42.080  68.302 1.00 20.41 ?  367  ARG B HH22 1 
ATOM   11233 N N    . LYS B 1 402 ? -17.751 38.247  72.326 1.00 17.03 ?  368  LYS B N    1 
ATOM   11234 C CA   . LYS B 1 402 ? -18.989 38.996  72.452 1.00 19.48 ?  368  LYS B CA   1 
ATOM   11235 C C    . LYS B 1 402 ? -18.879 40.322  71.710 1.00 18.73 ?  368  LYS B C    1 
ATOM   11236 O O    . LYS B 1 402 ? -17.855 41.018  71.804 1.00 19.08 ?  368  LYS B O    1 
ATOM   11237 C CB   . LYS B 1 402 ? -19.311 39.161  73.947 1.00 27.12 ?  368  LYS B CB   1 
ATOM   11238 C CG   . LYS B 1 402 ? -20.229 40.276  74.359 1.00 33.95 ?  368  LYS B CG   1 
ATOM   11239 C CD   . LYS B 1 402 ? -20.200 40.450  75.902 1.00 45.14 ?  368  LYS B CD   1 
ATOM   11240 C CE   . LYS B 1 402 ? -21.450 41.126  76.514 1.00 43.01 ?  368  LYS B CE   1 
ATOM   11241 N NZ   . LYS B 1 402 ? -22.795 40.702  75.979 1.00 33.25 ?  368  LYS B NZ   1 
ATOM   11242 H H    . LYS B 1 402 ? -17.086 38.602  72.740 1.00 20.43 ?  368  LYS B H    1 
ATOM   11243 H HA   . LYS B 1 402 ? -19.733 38.537  72.031 1.00 23.38 ?  368  LYS B HA   1 
ATOM   11244 H HB2  . LYS B 1 402 ? -19.723 38.337  74.252 1.00 32.54 ?  368  LYS B HB2  1 
ATOM   11245 H HB3  . LYS B 1 402 ? -18.473 39.305  74.414 1.00 32.54 ?  368  LYS B HB3  1 
ATOM   11246 H HG2  . LYS B 1 402 ? -19.939 41.106  73.948 1.00 40.73 ?  368  LYS B HG2  1 
ATOM   11247 H HG3  . LYS B 1 402 ? -21.136 40.070  74.087 1.00 40.73 ?  368  LYS B HG3  1 
ATOM   11248 H HD2  . LYS B 1 402 ? -20.118 39.573  76.308 1.00 54.17 ?  368  LYS B HD2  1 
ATOM   11249 H HD3  . LYS B 1 402 ? -19.433 40.996  76.135 1.00 54.17 ?  368  LYS B HD3  1 
ATOM   11250 H HE2  . LYS B 1 402 ? -21.455 40.940  77.466 1.00 51.61 ?  368  LYS B HE2  1 
ATOM   11251 H HE3  . LYS B 1 402 ? -21.377 42.082  76.364 1.00 51.61 ?  368  LYS B HE3  1 
ATOM   11252 H HZ1  . LYS B 1 402 ? -23.443 41.137  76.405 1.00 39.90 ?  368  LYS B HZ1  1 
ATOM   11253 H HZ2  . LYS B 1 402 ? -22.847 40.884  75.109 1.00 39.90 ?  368  LYS B HZ2  1 
ATOM   11254 H HZ3  . LYS B 1 402 ? -22.907 39.827  76.098 1.00 39.90 ?  368  LYS B HZ3  1 
ATOM   11255 N N    . PHE B 1 403 ? -19.922 40.651  70.949 1.00 17.57 ?  369  PHE B N    1 
ATOM   11256 C CA   . PHE B 1 403 ? -20.100 41.924  70.290 1.00 16.34 ?  369  PHE B CA   1 
ATOM   11257 C C    . PHE B 1 403 ? -21.383 42.552  70.840 1.00 17.13 ?  369  PHE B C    1 
ATOM   11258 O O    . PHE B 1 403 ? -22.182 41.872  71.485 1.00 20.42 ?  369  PHE B O    1 
ATOM   11259 C CB   . PHE B 1 403 ? -20.212 41.741  68.762 1.00 16.70 ?  369  PHE B CB   1 
ATOM   11260 C CG   . PHE B 1 403 ? -18.979 41.148  68.112 1.00 15.80 ?  369  PHE B CG   1 
ATOM   11261 C CD1  . PHE B 1 403 ? -18.692 39.808  68.195 1.00 14.45 ?  369  PHE B CD1  1 
ATOM   11262 C CD2  . PHE B 1 403 ? -18.099 41.960  67.413 1.00 15.80 ?  369  PHE B CD2  1 
ATOM   11263 C CE1  . PHE B 1 403 ? -17.549 39.293  67.617 1.00 16.60 ?  369  PHE B CE1  1 
ATOM   11264 C CE2  . PHE B 1 403 ? -16.977 41.446  66.815 1.00 15.89 ?  369  PHE B CE2  1 
ATOM   11265 C CZ   . PHE B 1 403 ? -16.697 40.136  66.898 1.00 15.81 ?  369  PHE B CZ   1 
ATOM   11266 H H    . PHE B 1 403 ? -20.575 40.113  70.795 1.00 21.08 ?  369  PHE B H    1 
ATOM   11267 H HA   . PHE B 1 403 ? -19.347 42.510  70.463 1.00 19.61 ?  369  PHE B HA   1 
ATOM   11268 H HB2  . PHE B 1 403 ? -20.957 41.148  68.575 1.00 20.04 ?  369  PHE B HB2  1 
ATOM   11269 H HB3  . PHE B 1 403 ? -20.370 42.608  68.357 1.00 20.04 ?  369  PHE B HB3  1 
ATOM   11270 H HD1  . PHE B 1 403 ? -19.274 39.241  68.645 1.00 17.35 ?  369  PHE B HD1  1 
ATOM   11271 H HD2  . PHE B 1 403 ? -18.273 42.871  67.349 1.00 18.96 ?  369  PHE B HD2  1 
ATOM   11272 H HE1  . PHE B 1 403 ? -17.346 38.390  67.706 1.00 19.92 ?  369  PHE B HE1  1 
ATOM   11273 H HE2  . PHE B 1 403 ? -16.405 42.011  66.347 1.00 19.07 ?  369  PHE B HE2  1 
ATOM   11274 H HZ   . PHE B 1 403 ? -15.941 39.791  66.480 1.00 18.97 ?  369  PHE B HZ   1 
ATOM   11275 N N    . GLU B 1 404 ? -21.587 43.831  70.542 1.00 19.69 ?  370  GLU B N    1 
ATOM   11276 C CA   . GLU B 1 404 ? -22.751 44.526  71.097 1.00 18.64 ?  370  GLU B CA   1 
ATOM   11277 C C    . GLU B 1 404 ? -24.046 43.773  70.810 1.00 22.61 ?  370  GLU B C    1 
ATOM   11278 O O    . GLU B 1 404 ? -24.930 43.667  71.683 1.00 23.57 ?  370  GLU B O    1 
ATOM   11279 C CB   . GLU B 1 404 ? -22.833 45.968  70.571 1.00 21.75 ?  370  GLU B CB   1 
ATOM   11280 C CG   . GLU B 1 404 ? -21.963 46.961  71.319 1.00 29.47 ?  370  GLU B CG   1 
ATOM   11281 C CD   . GLU B 1 404 ? -21.651 48.274  70.578 1.00 46.63 ?  370  GLU B CD   1 
ATOM   11282 O OE1  . GLU B 1 404 ? -21.772 48.370  69.332 1.00 38.55 ?  370  GLU B OE1  1 
ATOM   11283 O OE2  . GLU B 1 404 ? -21.270 49.240  71.275 1.00 55.64 ?  370  GLU B OE2  1 
ATOM   11284 H H    . GLU B 1 404 ? -21.083 44.309  70.035 1.00 23.63 ?  370  GLU B H    1 
ATOM   11285 H HA   . GLU B 1 404 ? -22.640 44.574  72.060 1.00 22.36 ?  370  GLU B HA   1 
ATOM   11286 H HB2  . GLU B 1 404 ? -22.554 45.974  69.643 1.00 26.10 ?  370  GLU B HB2  1 
ATOM   11287 H HB3  . GLU B 1 404 ? -23.752 46.271  70.644 1.00 26.10 ?  370  GLU B HB3  1 
ATOM   11288 H HG2  . GLU B 1 404 ? -22.413 47.198  72.145 1.00 35.36 ?  370  GLU B HG2  1 
ATOM   11289 H HG3  . GLU B 1 404 ? -21.114 46.534  71.514 1.00 35.36 ?  370  GLU B HG3  1 
ATOM   11290 N N    . ASN B 1 405 ? -24.179 43.213  69.603 1.00 19.00 ?  371  ASN B N    1 
ATOM   11291 C CA   . ASN B 1 405 ? -25.415 42.571  69.172 1.00 19.88 ?  371  ASN B CA   1 
ATOM   11292 C C    . ASN B 1 405 ? -25.232 41.111  68.767 1.00 16.78 ?  371  ASN B C    1 
ATOM   11293 O O    . ASN B 1 405 ? -26.089 40.549  68.079 1.00 19.25 ?  371  ASN B O    1 
ATOM   11294 C CB   . ASN B 1 405 ? -26.047 43.362  68.030 1.00 18.95 ?  371  ASN B CB   1 
ATOM   11295 C CG   . ASN B 1 405 ? -26.346 44.792  68.419 1.00 25.44 ?  371  ASN B CG   1 
ATOM   11296 O OD1  . ASN B 1 405 ? -25.623 45.709  68.065 1.00 29.05 ?  371  ASN B OD1  1 
ATOM   11297 N ND2  . ASN B 1 405 ? -27.426 44.983  69.148 1.00 34.31 ?  371  ASN B ND2  1 
ATOM   11298 H H    . ASN B 1 405 ? -23.556 43.195  69.010 1.00 22.80 ?  371  ASN B H    1 
ATOM   11299 H HA   . ASN B 1 405 ? -26.025 42.570  69.926 1.00 23.86 ?  371  ASN B HA   1 
ATOM   11300 H HB2  . ASN B 1 405 ? -25.437 43.375  67.276 1.00 22.74 ?  371  ASN B HB2  1 
ATOM   11301 H HB3  . ASN B 1 405 ? -26.882 42.938  67.774 1.00 22.74 ?  371  ASN B HB3  1 
ATOM   11302 H HD21 . ASN B 1 405 ? -27.642 45.777  69.397 1.00 41.18 ?  371  ASN B HD21 1 
ATOM   11303 H HD22 . ASN B 1 405 ? -27.915 44.313  69.375 1.00 41.18 ?  371  ASN B HD22 1 
ATOM   11304 N N    . LEU B 1 406 ? -24.172 40.447  69.237 1.00 17.29 ?  372  LEU B N    1 
ATOM   11305 C CA   . LEU B 1 406 ? -23.908 39.086  68.816 1.00 16.17 ?  372  LEU B CA   1 
ATOM   11306 C C    . LEU B 1 406 ? -22.982 38.401  69.787 1.00 17.48 ?  372  LEU B C    1 
ATOM   11307 O O    . LEU B 1 406 ? -22.015 39.001  70.251 1.00 19.80 ?  372  LEU B O    1 
ATOM   11308 C CB   . LEU B 1 406 ? -23.261 39.062  67.407 1.00 17.56 ?  372  LEU B CB   1 
ATOM   11309 C CG   . LEU B 1 406 ? -22.700 37.742  66.912 1.00 16.14 ?  372  LEU B CG   1 
ATOM   11310 C CD1  . LEU B 1 406 ? -23.759 36.684  66.612 1.00 16.31 ?  372  LEU B CD1  1 
ATOM   11311 C CD2  . LEU B 1 406 ? -21.849 37.928  65.647 1.00 16.57 ?  372  LEU B CD2  1 
ATOM   11312 H H    . LEU B 1 406 ? -23.601 40.767  69.795 1.00 20.74 ?  372  LEU B H    1 
ATOM   11313 H HA   . LEU B 1 406 ? -24.749 38.602  68.811 1.00 19.41 ?  372  LEU B HA   1 
ATOM   11314 H HB2  . LEU B 1 406 ? -23.935 39.337  66.767 1.00 21.07 ?  372  LEU B HB2  1 
ATOM   11315 H HB3  . LEU B 1 406 ? -22.526 39.695  67.408 1.00 21.07 ?  372  LEU B HB3  1 
ATOM   11316 H HG   . LEU B 1 406 ? -22.155 37.415  67.645 1.00 19.37 ?  372  LEU B HG   1 
ATOM   11317 H HD11 . LEU B 1 406 ? -23.318 35.858  66.360 1.00 19.58 ?  372  LEU B HD11 1 
ATOM   11318 H HD12 . LEU B 1 406 ? -24.298 36.542  67.406 1.00 19.58 ?  372  LEU B HD12 1 
ATOM   11319 H HD13 . LEU B 1 406 ? -24.320 36.996  65.884 1.00 19.58 ?  372  LEU B HD13 1 
ATOM   11320 H HD21 . LEU B 1 406 ? -21.425 37.085  65.424 1.00 19.89 ?  372  LEU B HD21 1 
ATOM   11321 H HD22 . LEU B 1 406 ? -22.424 38.211  64.918 1.00 19.89 ?  372  LEU B HD22 1 
ATOM   11322 H HD23 . LEU B 1 406 ? -21.174 38.603  65.817 1.00 19.89 ?  372  LEU B HD23 1 
ATOM   11323 N N    . ASP B 1 407 ? -23.262 37.142  70.081 1.00 17.79 ?  373  ASP B N    1 
ATOM   11324 C CA   . ASP B 1 407 ? -22.326 36.285  70.778 1.00 18.13 ?  373  ASP B CA   1 
ATOM   11325 C C    . ASP B 1 407 ? -21.894 35.161  69.859 1.00 17.46 ?  373  ASP B C    1 
ATOM   11326 O O    . ASP B 1 407 ? -22.731 34.504  69.217 1.00 17.32 ?  373  ASP B O    1 
ATOM   11327 C CB   . ASP B 1 407 ? -22.865 35.795  72.126 1.00 23.49 ?  373  ASP B CB   1 
ATOM   11328 C CG   . ASP B 1 407 ? -22.887 36.930  73.157 1.00 24.03 ?  373  ASP B CG   1 
ATOM   11329 O OD1  . ASP B 1 407 ? -21.834 37.204  73.771 1.00 36.04 ?  373  ASP B OD1  1 
ATOM   11330 O OD2  . ASP B 1 407 ? -23.915 37.572  73.325 1.00 30.97 ?  373  ASP B OD2  1 
ATOM   11331 H H    . ASP B 1 407 ? -24.005 36.757  69.882 1.00 21.34 ?  373  ASP B H    1 
ATOM   11332 H HA   . ASP B 1 407 ? -21.526 36.788  70.998 1.00 21.75 ?  373  ASP B HA   1 
ATOM   11333 H HB2  . ASP B 1 407 ? -23.771 35.467  72.010 1.00 28.19 ?  373  ASP B HB2  1 
ATOM   11334 H HB3  . ASP B 1 407 ? -22.296 35.085  72.462 1.00 28.19 ?  373  ASP B HB3  1 
ATOM   11335 N N    . VAL B 1 408 ? -20.577 34.940  69.791 1.00 16.85 ?  374  VAL B N    1 
ATOM   11336 C CA   . VAL B 1 408 ? -19.991 33.941  68.918 1.00 14.49 ?  374  VAL B CA   1 
ATOM   11337 C C    . VAL B 1 408 ? -19.480 32.795  69.761 1.00 16.10 ?  374  VAL B C    1 
ATOM   11338 O O    . VAL B 1 408 ? -18.760 33.008  70.756 1.00 16.41 ?  374  VAL B O    1 
ATOM   11339 C CB   . VAL B 1 408 ? -18.827 34.527  68.102 1.00 14.95 ?  374  VAL B CB   1 
ATOM   11340 C CG1  . VAL B 1 408 ? -18.210 33.484  67.234 1.00 16.59 ?  374  VAL B CG1  1 
ATOM   11341 C CG2  . VAL B 1 408 ? -19.338 35.687  67.298 1.00 16.17 ?  374  VAL B CG2  1 
ATOM   11342 H H    . VAL B 1 408 ? -19.996 35.372  70.255 1.00 20.23 ?  374  VAL B H    1 
ATOM   11343 H HA   . VAL B 1 408 ? -20.681 33.613  68.319 1.00 17.39 ?  374  VAL B HA   1 
ATOM   11344 H HB   . VAL B 1 408 ? -18.127 34.843  68.695 1.00 17.94 ?  374  VAL B HB   1 
ATOM   11345 H HG11 . VAL B 1 408 ? -17.564 33.904  66.645 1.00 19.91 ?  374  VAL B HG11 1 
ATOM   11346 H HG12 . VAL B 1 408 ? -17.768 32.827  67.795 1.00 19.91 ?  374  VAL B HG12 1 
ATOM   11347 H HG13 . VAL B 1 408 ? -18.906 33.056  66.711 1.00 19.91 ?  374  VAL B HG13 1 
ATOM   11348 H HG21 . VAL B 1 408 ? -18.631 36.001  66.712 1.00 19.40 ?  374  VAL B HG21 1 
ATOM   11349 H HG22 . VAL B 1 408 ? -20.099 35.396  66.772 1.00 19.40 ?  374  VAL B HG22 1 
ATOM   11350 H HG23 . VAL B 1 408 ? -19.605 36.397  67.902 1.00 19.40 ?  374  VAL B HG23 1 
ATOM   11351 N N    . TRP B 1 409 ? -19.758 31.577  69.332 1.00 17.19 ?  375  TRP B N    1 
ATOM   11352 C CA   . TRP B 1 409 ? -19.175 30.379  69.894 1.00 16.66 ?  375  TRP B CA   1 
ATOM   11353 C C    . TRP B 1 409 ? -18.658 29.555  68.721 1.00 17.87 ?  375  TRP B C    1 
ATOM   11354 O O    . TRP B 1 409 ? -19.424 29.317  67.775 1.00 19.51 ?  375  TRP B O    1 
ATOM   11355 C CB   . TRP B 1 409 ? -20.271 29.640  70.710 1.00 20.52 ?  375  TRP B CB   1 
ATOM   11356 C CG   . TRP B 1 409 ? -19.794 28.414  71.218 1.00 21.98 ?  375  TRP B CG   1 
ATOM   11357 C CD1  . TRP B 1 409 ? -19.146 28.204  72.410 1.00 23.15 ?  375  TRP B CD1  1 
ATOM   11358 C CD2  . TRP B 1 409 ? -19.851 27.151  70.556 1.00 19.36 ?  375  TRP B CD2  1 
ATOM   11359 N NE1  . TRP B 1 409 ? -18.800 26.867  72.520 1.00 23.41 ?  375  TRP B NE1  1 
ATOM   11360 C CE2  . TRP B 1 409 ? -19.205 26.211  71.384 1.00 22.64 ?  375  TRP B CE2  1 
ATOM   11361 C CE3  . TRP B 1 409 ? -20.377 26.722  69.323 1.00 21.37 ?  375  TRP B CE3  1 
ATOM   11362 C CZ2  . TRP B 1 409 ? -19.092 24.868  71.020 1.00 23.12 ?  375  TRP B CZ2  1 
ATOM   11363 C CZ3  . TRP B 1 409 ? -20.260 25.425  68.979 1.00 19.76 ?  375  TRP B CZ3  1 
ATOM   11364 C CH2  . TRP B 1 409 ? -19.617 24.493  69.828 1.00 21.36 ?  375  TRP B CH2  1 
ATOM   11365 H H    . TRP B 1 409 ? -20.306 31.414  68.689 1.00 20.63 ?  375  TRP B H    1 
ATOM   11366 H HA   . TRP B 1 409 ? -18.424 30.547  70.486 1.00 20.00 ?  375  TRP B HA   1 
ATOM   11367 H HB2  . TRP B 1 409 ? -20.545 30.195  71.457 1.00 24.63 ?  375  TRP B HB2  1 
ATOM   11368 H HB3  . TRP B 1 409 ? -21.031 29.458  70.136 1.00 24.63 ?  375  TRP B HB3  1 
ATOM   11369 H HD1  . TRP B 1 409 ? -18.966 28.858  73.046 1.00 27.78 ?  375  TRP B HD1  1 
ATOM   11370 H HE1  . TRP B 1 409 ? -18.399 26.507  73.189 1.00 28.09 ?  375  TRP B HE1  1 
ATOM   11371 H HE3  . TRP B 1 409 ? -20.798 27.325  68.754 1.00 25.65 ?  375  TRP B HE3  1 
ATOM   11372 H HZ2  . TRP B 1 409 ? -18.672 24.252  71.576 1.00 27.74 ?  375  TRP B HZ2  1 
ATOM   11373 H HZ3  . TRP B 1 409 ? -20.610 25.136  68.168 1.00 23.71 ?  375  TRP B HZ3  1 
ATOM   11374 H HH2  . TRP B 1 409 ? -19.553 23.604  69.562 1.00 25.63 ?  375  TRP B HH2  1 
ATOM   11375 N N    . LEU B 1 410 ? -17.382 29.173  68.734 1.00 15.40 ?  376  LEU B N    1 
ATOM   11376 C CA   . LEU B 1 410 ? -16.706 28.515  67.623 1.00 16.98 ?  376  LEU B CA   1 
ATOM   11377 C C    . LEU B 1 410 ? -15.994 27.261  68.128 1.00 17.99 ?  376  LEU B C    1 
ATOM   11378 O O    . LEU B 1 410 ? -15.192 27.368  69.062 1.00 19.70 ?  376  LEU B O    1 
ATOM   11379 C CB   . LEU B 1 410 ? -15.616 29.452  67.030 1.00 15.00 ?  376  LEU B CB   1 
ATOM   11380 C CG   . LEU B 1 410 ? -14.650 28.912  66.015 1.00 17.62 ?  376  LEU B CG   1 
ATOM   11381 C CD1  . LEU B 1 410 ? -15.400 28.474  64.773 1.00 18.24 ?  376  LEU B CD1  1 
ATOM   11382 C CD2  . LEU B 1 410 ? -13.569 29.972  65.652 1.00 20.83 ?  376  LEU B CD2  1 
ATOM   11383 H H    . LEU B 1 410 ? -16.864 29.291  69.411 1.00 18.47 ?  376  LEU B H    1 
ATOM   11384 H HA   . LEU B 1 410 ? -17.365 28.274  66.953 1.00 20.37 ?  376  LEU B HA   1 
ATOM   11385 H HB2  . LEU B 1 410 ? -16.074 30.193  66.603 1.00 18.00 ?  376  LEU B HB2  1 
ATOM   11386 H HB3  . LEU B 1 410 ? -15.080 29.776  67.771 1.00 18.00 ?  376  LEU B HB3  1 
ATOM   11387 H HG   . LEU B 1 410 ? -14.191 28.145  66.392 1.00 21.14 ?  376  LEU B HG   1 
ATOM   11388 H HD11 . LEU B 1 410 ? -14.763 28.156  64.115 1.00 21.89 ?  376  LEU B HD11 1 
ATOM   11389 H HD12 . LEU B 1 410 ? -16.015 27.762  65.010 1.00 21.89 ?  376  LEU B HD12 1 
ATOM   11390 H HD13 . LEU B 1 410 ? -15.892 29.231  64.418 1.00 21.89 ?  376  LEU B HD13 1 
ATOM   11391 H HD21 . LEU B 1 410 ? -12.971 29.598  64.986 1.00 24.99 ?  376  LEU B HD21 1 
ATOM   11392 H HD22 . LEU B 1 410 ? -14.007 30.761  65.297 1.00 24.99 ?  376  LEU B HD22 1 
ATOM   11393 H HD23 . LEU B 1 410 ? -13.070 30.202  66.452 1.00 24.99 ?  376  LEU B HD23 1 
ATOM   11394 N N    . ASN B 1 411 ? -16.209 26.094  67.510 1.00 15.64 ?  377  ASN B N    1 
ATOM   11395 C CA   . ASN B 1 411 ? -15.464 24.884  67.832 1.00 14.99 ?  377  ASN B CA   1 
ATOM   11396 C C    . ASN B 1 411 ? -14.697 24.425  66.595 1.00 14.16 ?  377  ASN B C    1 
ATOM   11397 O O    . ASN B 1 411 ? -15.276 23.832  65.673 1.00 15.69 ?  377  ASN B O    1 
ATOM   11398 C CB   . ASN B 1 411 ? -16.412 23.777  68.336 1.00 16.60 ?  377  ASN B CB   1 
ATOM   11399 C CG   . ASN B 1 411 ? -15.668 22.590  68.883 1.00 18.69 ?  377  ASN B CG   1 
ATOM   11400 O OD1  . ASN B 1 411 ? -14.465 22.451  68.715 1.00 19.42 ?  377  ASN B OD1  1 
ATOM   11401 N ND2  . ASN B 1 411 ? -16.400 21.709  69.561 1.00 20.27 ?  377  ASN B ND2  1 
ATOM   11402 H H    . ASN B 1 411 ? -16.795 25.982  66.890 1.00 18.76 ?  377  ASN B H    1 
ATOM   11403 H HA   . ASN B 1 411 ? -14.817 25.086  68.526 1.00 17.98 ?  377  ASN B HA   1 
ATOM   11404 H HB2  . ASN B 1 411 ? -16.970 24.135  69.043 1.00 19.91 ?  377  ASN B HB2  1 
ATOM   11405 H HB3  . ASN B 1 411 ? -16.964 23.472  67.599 1.00 19.91 ?  377  ASN B HB3  1 
ATOM   11406 H HD21 . ASN B 1 411 ? -16.029 21.010  69.898 1.00 24.33 ?  377  ASN B HD21 1 
ATOM   11407 H HD22 . ASN B 1 411 ? -17.244 21.839  69.663 1.00 24.33 ?  377  ASN B HD22 1 
ATOM   11408 N N    . LEU B 1 412 ? -13.382 24.640  66.583 1.00 14.13 ?  378  LEU B N    1 
ATOM   11409 C CA   . LEU B 1 412 ? -12.605 24.232  65.425 1.00 14.67 ?  378  LEU B CA   1 
ATOM   11410 C C    . LEU B 1 412 ? -12.625 22.729  65.239 1.00 17.21 ?  378  LEU B C    1 
ATOM   11411 O O    . LEU B 1 412 ? -12.496 22.239  64.107 1.00 19.85 ?  378  LEU B O    1 
ATOM   11412 C CB   . LEU B 1 412 ? -11.155 24.719  65.571 1.00 15.51 ?  378  LEU B CB   1 
ATOM   11413 C CG   . LEU B 1 412 ? -10.955 26.206  65.591 1.00 14.31 ?  378  LEU B CG   1 
ATOM   11414 C CD1  . LEU B 1 412 ? -9.475  26.490  65.755 1.00 18.65 ?  378  LEU B CD1  1 
ATOM   11415 C CD2  . LEU B 1 412 ? -11.459 26.855  64.317 1.00 18.57 ?  378  LEU B CD2  1 
ATOM   11416 H H    . LEU B 1 412 ? -12.932 25.010  67.216 1.00 16.95 ?  378  LEU B H    1 
ATOM   11417 H HA   . LEU B 1 412 ? -12.990 24.641  64.634 1.00 17.60 ?  378  LEU B HA   1 
ATOM   11418 H HB2  . LEU B 1 412 ? -10.802 24.371  66.405 1.00 18.61 ?  378  LEU B HB2  1 
ATOM   11419 H HB3  . LEU B 1 412 ? -10.643 24.371  64.823 1.00 18.61 ?  378  LEU B HB3  1 
ATOM   11420 H HG   . LEU B 1 412 ? -11.459 26.586  66.327 1.00 17.18 ?  378  LEU B HG   1 
ATOM   11421 H HD11 . LEU B 1 412 ? -9.331  27.449  65.712 1.00 22.38 ?  378  LEU B HD11 1 
ATOM   11422 H HD12 . LEU B 1 412 ? -9.182  26.150  66.615 1.00 22.38 ?  378  LEU B HD12 1 
ATOM   11423 H HD13 . LEU B 1 412 ? -8.988  26.050  65.041 1.00 22.38 ?  378  LEU B HD13 1 
ATOM   11424 H HD21 . LEU B 1 412 ? -11.141 27.770  64.282 1.00 22.29 ?  378  LEU B HD21 1 
ATOM   11425 H HD22 . LEU B 1 412 ? -11.124 26.358  63.555 1.00 22.29 ?  378  LEU B HD22 1 
ATOM   11426 H HD23 . LEU B 1 412 ? -12.429 26.842  64.319 1.00 22.29 ?  378  LEU B HD23 1 
ATOM   11427 N N    . GLU B 1 413 ? -12.765 21.964  66.327 1.00 15.72 ?  379  GLU B N    1 
ATOM   11428 C CA   . GLU B 1 413 ? -12.635 20.520  66.249 1.00 19.43 ?  379  GLU B CA   1 
ATOM   11429 C C    . GLU B 1 413 ? -13.785 19.901  65.472 1.00 19.15 ?  379  GLU B C    1 
ATOM   11430 O O    . GLU B 1 413 ? -13.581 18.952  64.705 1.00 22.53 ?  379  GLU B O    1 
ATOM   11431 C CB   . GLU B 1 413 ? -12.594 19.945  67.667 1.00 21.49 ?  379  GLU B CB   1 
ATOM   11432 C CG   . GLU B 1 413 ? -12.292 18.469  67.783 1.00 35.19 ?  379  GLU B CG   1 
ATOM   11433 C CD   . GLU B 1 413 ? -11.548 18.146  69.063 1.00 46.29 ?  379  GLU B CD   1 
ATOM   11434 O OE1  . GLU B 1 413 ? -10.868 17.099  69.106 1.00 49.58 ?  379  GLU B OE1  1 
ATOM   11435 O OE2  . GLU B 1 413 ? -11.642 18.943  70.019 1.00 48.95 ?  379  GLU B OE2  1 
ATOM   11436 H H    . GLU B 1 413 ? -12.935 22.260  67.116 1.00 18.86 ?  379  GLU B H    1 
ATOM   11437 H HA   . GLU B 1 413 ? -11.810 20.300  65.789 1.00 23.32 ?  379  GLU B HA   1 
ATOM   11438 H HB2  . GLU B 1 413 ? -11.907 20.417  68.163 1.00 25.78 ?  379  GLU B HB2  1 
ATOM   11439 H HB3  . GLU B 1 413 ? -13.460 20.092  68.077 1.00 25.78 ?  379  GLU B HB3  1 
ATOM   11440 H HG2  . GLU B 1 413 ? -13.124 17.971  67.781 1.00 42.22 ?  379  GLU B HG2  1 
ATOM   11441 H HG3  . GLU B 1 413 ? -11.740 18.196  67.033 1.00 42.22 ?  379  GLU B HG3  1 
ATOM   11442 N N    . THR B 1 414 ? -15.001 20.385  65.688 1.00 17.59 ?  380  THR B N    1 
ATOM   11443 C CA   . THR B 1 414 ? -16.170 19.873  64.992 1.00 17.08 ?  380  THR B CA   1 
ATOM   11444 C C    . THR B 1 414 ? -16.486 20.683  63.764 1.00 19.65 ?  380  THR B C    1 
ATOM   11445 O O    . THR B 1 414 ? -17.418 20.322  63.023 1.00 19.54 ?  380  THR B O    1 
ATOM   11446 C CB   . THR B 1 414 ? -17.372 19.889  65.912 1.00 18.23 ?  380  THR B CB   1 
ATOM   11447 O OG1  . THR B 1 414 ? -17.552 21.190  66.428 1.00 19.98 ?  380  THR B OG1  1 
ATOM   11448 C CG2  . THR B 1 414 ? -17.144 18.928  67.061 1.00 23.67 ?  380  THR B CG2  1 
ATOM   11449 H H    . THR B 1 414 ? -15.176 21.019  66.242 1.00 21.11 ?  380  THR B H    1 
ATOM   11450 H HA   . THR B 1 414 ? -16.006 18.954  64.730 1.00 20.50 ?  380  THR B HA   1 
ATOM   11451 H HB   . THR B 1 414 ? -18.167 19.622  65.425 1.00 21.88 ?  380  THR B HB   1 
ATOM   11452 H HG1  . THR B 1 414 ? -17.806 21.709  65.818 1.00 23.97 ?  380  THR B HG1  1 
ATOM   11453 H HG21 . THR B 1 414 ? -17.870 18.998  67.700 1.00 28.40 ?  380  THR B HG21 1 
ATOM   11454 H HG22 . THR B 1 414 ? -17.103 18.018  66.729 1.00 28.40 ?  380  THR B HG22 1 
ATOM   11455 H HG23 . THR B 1 414 ? -16.310 19.138  67.508 1.00 28.40 ?  380  THR B HG23 1 
ATOM   11456 N N    . GLN B 1 415 ? -15.753 21.775  63.544 1.00 17.26 ?  381  GLN B N    1 
ATOM   11457 C CA   . GLN B 1 415 ? -16.036 22.718  62.463 1.00 20.11 ?  381  GLN B CA   1 
ATOM   11458 C C    . GLN B 1 415 ? -17.461 23.232  62.533 1.00 18.79 ?  381  GLN B C    1 
ATOM   11459 O O    . GLN B 1 415 ? -18.189 23.286  61.524 1.00 22.10 ?  381  GLN B O    1 
ATOM   11460 C CB   . GLN B 1 415 ? -15.751 22.095  61.093 1.00 20.73 ?  381  GLN B CB   1 
ATOM   11461 C CG   . GLN B 1 415 ? -14.362 21.615  60.896 1.00 24.60 ?  381  GLN B CG   1 
ATOM   11462 C CD   . GLN B 1 415 ? -14.000 21.507  59.438 1.00 28.66 ?  381  GLN B CD   1 
ATOM   11463 O OE1  . GLN B 1 415 ? -14.708 22.010  58.564 1.00 36.54 ?  381  GLN B OE1  1 
ATOM   11464 N NE2  . GLN B 1 415 ? -12.921 20.848  59.168 1.00 27.61 ?  381  GLN B NE2  1 
ATOM   11465 H H    . GLN B 1 415 ? -15.071 21.996  64.019 1.00 20.71 ?  381  GLN B H    1 
ATOM   11466 H HA   . GLN B 1 415 ? -15.446 23.480  62.574 1.00 24.13 ?  381  GLN B HA   1 
ATOM   11467 H HB2  . GLN B 1 415 ? -16.340 21.334  60.974 1.00 24.87 ?  381  GLN B HB2  1 
ATOM   11468 H HB3  . GLN B 1 415 ? -15.927 22.761  60.411 1.00 24.87 ?  381  GLN B HB3  1 
ATOM   11469 H HG2  . GLN B 1 415 ? -13.747 22.237  61.314 1.00 29.52 ?  381  GLN B HG2  1 
ATOM   11470 H HG3  . GLN B 1 415 ? -14.269 20.736  61.296 1.00 29.52 ?  381  GLN B HG3  1 
ATOM   11471 H HE21 . GLN B 1 415 ? -12.458 20.503  59.805 1.00 33.13 ?  381  GLN B HE21 1 
ATOM   11472 H HE22 . GLN B 1 415 ? -12.667 20.756  58.352 1.00 33.13 ?  381  GLN B HE22 1 
ATOM   11473 N N    . THR B 1 416 ? -17.887 23.610  63.724 1.00 16.76 ?  382  THR B N    1 
ATOM   11474 C CA   . THR B 1 416 ? -19.198 24.200  63.890 1.00 19.58 ?  382  THR B CA   1 
ATOM   11475 C C    . THR B 1 416 ? -19.125 25.476  64.714 1.00 18.20 ?  382  THR B C    1 
ATOM   11476 O O    . THR B 1 416 ? -18.186 25.710  65.487 1.00 17.35 ?  382  THR B O    1 
ATOM   11477 C CB   . THR B 1 416 ? -20.207 23.216  64.454 1.00 34.59 ?  382  THR B CB   1 
ATOM   11478 O OG1  . THR B 1 416 ? -19.740 22.739  65.697 1.00 29.75 ?  382  THR B OG1  1 
ATOM   11479 C CG2  . THR B 1 416 ? -20.373 22.044  63.497 1.00 33.61 ?  382  THR B CG2  1 
ATOM   11480 H H    . THR B 1 416 ? -17.433 23.534  64.451 1.00 20.11 ?  382  THR B H    1 
ATOM   11481 H HA   . THR B 1 416 ? -19.527 24.469  63.018 1.00 23.50 ?  382  THR B HA   1 
ATOM   11482 H HB   . THR B 1 416 ? -21.068 23.648  64.573 1.00 41.51 ?  382  THR B HB   1 
ATOM   11483 H HG1  . THR B 1 416 ? -20.277 22.172  66.008 1.00 35.70 ?  382  THR B HG1  1 
ATOM   11484 H HG21 . THR B 1 416 ? -21.103 21.477  63.790 1.00 40.33 ?  382  THR B HG21 1 
ATOM   11485 H HG22 . THR B 1 416 ? -20.566 22.369  62.604 1.00 40.33 ?  382  THR B HG22 1 
ATOM   11486 H HG23 . THR B 1 416 ? -19.558 21.518  63.472 1.00 40.33 ?  382  THR B HG23 1 
ATOM   11487 N N    . ALA B 1 417 ? -20.112 26.341  64.536 1.00 15.58 ?  383  ALA B N    1 
ATOM   11488 C CA   . ALA B 1 417 ? -20.202 27.551  65.313 1.00 15.38 ?  383  ALA B CA   1 
ATOM   11489 C C    . ALA B 1 417 ? -21.664 27.867  65.574 1.00 15.56 ?  383  ALA B C    1 
ATOM   11490 O O    . ALA B 1 417 ? -22.570 27.442  64.829 1.00 18.43 ?  383  ALA B O    1 
ATOM   11491 C CB   . ALA B 1 417 ? -19.566 28.736  64.599 1.00 16.21 ?  383  ALA B CB   1 
ATOM   11492 H H    . ALA B 1 417 ? -20.746 26.242  63.963 1.00 18.70 ?  383  ALA B H    1 
ATOM   11493 H HA   . ALA B 1 417 ? -19.746 27.406  66.156 1.00 18.46 ?  383  ALA B HA   1 
ATOM   11494 H HB1  . ALA B 1 417 ? -19.526 29.488  65.210 1.00 19.45 ?  383  ALA B HB1  1 
ATOM   11495 H HB2  . ALA B 1 417 ? -18.671 28.492  64.317 1.00 19.45 ?  383  ALA B HB2  1 
ATOM   11496 H HB3  . ALA B 1 417 ? -20.105 28.966  63.826 1.00 19.45 ?  383  ALA B HB3  1 
ATOM   11497 N N    . THR B 1 418 ? -21.900 28.662  66.602 1.00 14.83 ?  384  THR B N    1 
ATOM   11498 C CA   . THR B 1 418 ? -23.199 29.183  66.951 1.00 17.12 ?  384  THR B CA   1 
ATOM   11499 C C    . THR B 1 418 ? -23.071 30.695  66.982 1.00 19.20 ?  384  THR B C    1 
ATOM   11500 O O    . THR B 1 418 ? -22.203 31.241  67.679 1.00 19.14 ?  384  THR B O    1 
ATOM   11501 C CB   . THR B 1 418 ? -23.628 28.654  68.329 1.00 19.08 ?  384  THR B CB   1 
ATOM   11502 O OG1  . THR B 1 418 ? -23.699 27.221  68.284 1.00 18.46 ?  384  THR B OG1  1 
ATOM   11503 C CG2  . THR B 1 418 ? -24.953 29.247  68.706 1.00 23.03 ?  384  THR B CG2  1 
ATOM   11504 H H    . THR B 1 418 ? -21.285 28.928  67.141 1.00 17.79 ?  384  THR B H    1 
ATOM   11505 H HA   . THR B 1 418 ? -23.869 28.925  66.299 1.00 20.55 ?  384  THR B HA   1 
ATOM   11506 H HB   . THR B 1 418 ? -22.986 28.905  69.012 1.00 22.90 ?  384  THR B HB   1 
ATOM   11507 H HG1  . THR B 1 418 ? -22.961 26.905  68.037 1.00 22.15 ?  384  THR B HG1  1 
ATOM   11508 H HG21 . THR B 1 418 ? -25.300 28.807  69.497 1.00 27.63 ?  384  THR B HG21 1 
ATOM   11509 H HG22 . THR B 1 418 ? -24.852 30.194  68.891 1.00 27.63 ?  384  THR B HG22 1 
ATOM   11510 H HG23 . THR B 1 418 ? -25.585 29.134  67.979 1.00 27.63 ?  384  THR B HG23 1 
ATOM   11511 N N    . LEU B 1 419 ? -23.900 31.381  66.219 1.00 16.85 ?  385  LEU B N    1 
ATOM   11512 C CA   . LEU B 1 419 ? -23.984 32.816  66.243 1.00 16.28 ?  385  LEU B CA   1 
ATOM   11513 C C    . LEU B 1 419 ? -25.306 33.184  66.911 1.00 20.45 ?  385  LEU B C    1 
ATOM   11514 O O    . LEU B 1 419 ? -26.377 32.890  66.364 1.00 21.97 ?  385  LEU B O    1 
ATOM   11515 C CB   . LEU B 1 419 ? -23.934 33.350  64.808 1.00 18.39 ?  385  LEU B CB   1 
ATOM   11516 C CG   . LEU B 1 419 ? -22.662 33.120  64.008 1.00 17.02 ?  385  LEU B CG   1 
ATOM   11517 C CD1  . LEU B 1 419 ? -22.672 33.838  62.678 1.00 17.77 ?  385  LEU B CD1  1 
ATOM   11518 C CD2  . LEU B 1 419 ? -21.399 33.523  64.789 1.00 19.48 ?  385  LEU B CD2  1 
ATOM   11519 H H    . LEU B 1 419 ? -24.443 31.018  65.659 1.00 20.21 ?  385  LEU B H    1 
ATOM   11520 H HA   . LEU B 1 419 ? -23.255 33.199  66.755 1.00 19.54 ?  385  LEU B HA   1 
ATOM   11521 H HB2  . LEU B 1 419 ? -24.655 32.931  64.312 1.00 22.06 ?  385  LEU B HB2  1 
ATOM   11522 H HB3  . LEU B 1 419 ? -24.071 34.309  64.845 1.00 22.06 ?  385  LEU B HB3  1 
ATOM   11523 H HG   . LEU B 1 419 ? -22.629 32.166  63.837 1.00 20.43 ?  385  LEU B HG   1 
ATOM   11524 H HD11 . LEU B 1 419 ? -21.850 33.638  62.205 1.00 21.32 ?  385  LEU B HD11 1 
ATOM   11525 H HD12 . LEU B 1 419 ? -23.434 33.534  62.161 1.00 21.32 ?  385  LEU B HD12 1 
ATOM   11526 H HD13 . LEU B 1 419 ? -22.739 34.793  62.836 1.00 21.32 ?  385  LEU B HD13 1 
ATOM   11527 H HD21 . LEU B 1 419 ? -20.626 33.425  64.212 1.00 23.38 ?  385  LEU B HD21 1 
ATOM   11528 H HD22 . LEU B 1 419 ? -21.485 34.447  65.073 1.00 23.38 ?  385  LEU B HD22 1 
ATOM   11529 H HD23 . LEU B 1 419 ? -21.309 32.947  65.564 1.00 23.38 ?  385  LEU B HD23 1 
ATOM   11530 N N    . THR B 1 420 ? -25.251 33.772  68.109 1.00 19.69 ?  386  THR B N    1 
ATOM   11531 C CA   . THR B 1 420 ? -26.453 34.203  68.834 1.00 19.81 ?  386  THR B CA   1 
ATOM   11532 C C    . THR B 1 420 ? -26.650 35.686  68.641 1.00 20.75 ?  386  THR B C    1 
ATOM   11533 O O    . THR B 1 420 ? -26.080 36.510  69.362 1.00 19.15 ?  386  THR B O    1 
ATOM   11534 C CB   . THR B 1 420 ? -26.361 33.838  70.305 1.00 21.39 ?  386  THR B CB   1 
ATOM   11535 O OG1  . THR B 1 420 ? -26.074 32.450  70.378 1.00 22.87 ?  386  THR B OG1  1 
ATOM   11536 C CG2  . THR B 1 420 ? -27.689 34.097  71.016 1.00 22.00 ?  386  THR B CG2  1 
ATOM   11537 H H    . THR B 1 420 ? -24.519 33.936  68.528 1.00 23.63 ?  386  THR B H    1 
ATOM   11538 H HA   . THR B 1 420 ? -27.220 33.752  68.448 1.00 23.78 ?  386  THR B HA   1 
ATOM   11539 H HB   . THR B 1 420 ? -25.678 34.368  70.744 1.00 25.66 ?  386  THR B HB   1 
ATOM   11540 H HG1  . THR B 1 420 ? -25.315 32.296  70.054 1.00 27.45 ?  386  THR B HG1  1 
ATOM   11541 H HG21 . THR B 1 420 ? -27.589 33.949  71.970 1.00 26.40 ?  386  THR B HG21 1 
ATOM   11542 H HG22 . THR B 1 420 ? -27.971 35.014  70.869 1.00 26.40 ?  386  THR B HG22 1 
ATOM   11543 H HG23 . THR B 1 420 ? -28.371 33.499  70.674 1.00 26.40 ?  386  THR B HG23 1 
ATOM   11544 N N    . TRP B 1 421 ? -27.486 36.032  67.668 1.00 17.30 ?  387  TRP B N    1 
ATOM   11545 C CA   . TRP B 1 421 ? -27.758 37.424  67.366 1.00 16.91 ?  387  TRP B CA   1 
ATOM   11546 C C    . TRP B 1 421 ? -28.775 38.006  68.353 1.00 21.27 ?  387  TRP B C    1 
ATOM   11547 O O    . TRP B 1 421 ? -29.715 37.312  68.766 1.00 23.45 ?  387  TRP B O    1 
ATOM   11548 C CB   . TRP B 1 421 ? -28.354 37.509  65.965 1.00 17.44 ?  387  TRP B CB   1 
ATOM   11549 C CG   . TRP B 1 421 ? -27.475 36.979  64.864 1.00 17.75 ?  387  TRP B CG   1 
ATOM   11550 C CD1  . TRP B 1 421 ? -27.511 35.751  64.328 1.00 16.12 ?  387  TRP B CD1  1 
ATOM   11551 C CD2  . TRP B 1 421 ? -26.428 37.700  64.182 1.00 17.32 ?  387  TRP B CD2  1 
ATOM   11552 N NE1  . TRP B 1 421 ? -26.563 35.636  63.312 1.00 16.10 ?  387  TRP B NE1  1 
ATOM   11553 C CE2  . TRP B 1 421 ? -25.882 36.818  63.225 1.00 16.44 ?  387  TRP B CE2  1 
ATOM   11554 C CE3  . TRP B 1 421 ? -25.898 38.995  64.298 1.00 17.58 ?  387  TRP B CE3  1 
ATOM   11555 C CZ2  . TRP B 1 421 ? -24.845 37.197  62.371 1.00 16.11 ?  387  TRP B CZ2  1 
ATOM   11556 C CZ3  . TRP B 1 421 ? -24.892 39.366  63.436 1.00 16.34 ?  387  TRP B CZ3  1 
ATOM   11557 C CH2  . TRP B 1 421 ? -24.373 38.458  62.485 1.00 16.02 ?  387  TRP B CH2  1 
ATOM   11558 H H    . TRP B 1 421 ? -27.908 35.474  67.168 1.00 20.76 ?  387  TRP B H    1 
ATOM   11559 H HA   . TRP B 1 421 ? -26.939 37.940  67.423 1.00 20.29 ?  387  TRP B HA   1 
ATOM   11560 H HB2  . TRP B 1 421 ? -29.177 36.996  65.951 1.00 20.93 ?  387  TRP B HB2  1 
ATOM   11561 H HB3  . TRP B 1 421 ? -28.539 38.440  65.766 1.00 20.93 ?  387  TRP B HB3  1 
ATOM   11562 H HD1  . TRP B 1 421 ? -28.086 35.072  64.596 1.00 19.35 ?  387  TRP B HD1  1 
ATOM   11563 H HE1  . TRP B 1 421 ? -26.429 34.941  62.823 1.00 19.33 ?  387  TRP B HE1  1 
ATOM   11564 H HE3  . TRP B 1 421 ? -26.219 39.587  64.940 1.00 21.10 ?  387  TRP B HE3  1 
ATOM   11565 H HZ2  . TRP B 1 421 ? -24.492 36.604  61.747 1.00 19.33 ?  387  TRP B HZ2  1 
ATOM   11566 H HZ3  . TRP B 1 421 ? -24.547 40.229  63.480 1.00 19.61 ?  387  TRP B HZ3  1 
ATOM   11567 H HH2  . TRP B 1 421 ? -23.687 38.736  61.921 1.00 19.22 ?  387  TRP B HH2  1 
ATOM   11568 N N    . LYS B 1 422 ? -28.587 39.266  68.723 1.00 21.18 ?  388  LYS B N    1 
ATOM   11569 C CA   . LYS B 1 422 ? -29.605 40.004  69.496 1.00 25.01 ?  388  LYS B CA   1 
ATOM   11570 C C    . LYS B 1 422 ? -30.263 40.973  68.546 1.00 36.48 ?  388  LYS B C    1 
ATOM   11571 O O    . LYS B 1 422 ? -29.583 41.910  68.120 1.00 29.93 ?  388  LYS B O    1 
ATOM   11572 C CB   . LYS B 1 422 ? -28.997 40.849  70.599 1.00 32.81 ?  388  LYS B CB   1 
ATOM   11573 C CG   . LYS B 1 422 ? -27.958 40.237  71.504 1.00 34.92 ?  388  LYS B CG   1 
ATOM   11574 C CD   . LYS B 1 422 ? -27.928 38.723  71.587 1.00 51.75 ?  388  LYS B CD   1 
ATOM   11575 C CE   . LYS B 1 422 ? -26.497 38.270  71.822 1.00 37.91 ?  388  LYS B CE   1 
ATOM   11576 N NZ   . LYS B 1 422 ? -26.403 36.830  72.103 1.00 37.69 ?  388  LYS B NZ   1 
ATOM   11577 H H    . LYS B 1 422 ? -27.882 39.724  68.544 1.00 25.42 ?  388  LYS B H    1 
ATOM   11578 H HA   . LYS B 1 422 ? -30.216 39.369  69.900 1.00 30.01 ?  388  LYS B HA   1 
ATOM   11579 H HB2  . LYS B 1 422 ? -28.577 41.616  70.180 1.00 39.38 ?  388  LYS B HB2  1 
ATOM   11580 H HB3  . LYS B 1 422 ? -29.722 41.141  71.174 1.00 39.38 ?  388  LYS B HB3  1 
ATOM   11581 H HG2  . LYS B 1 422 ? -27.084 40.520  71.192 1.00 41.90 ?  388  LYS B HG2  1 
ATOM   11582 H HG3  . LYS B 1 422 ? -28.112 40.566  72.403 1.00 41.90 ?  388  LYS B HG3  1 
ATOM   11583 H HD2  . LYS B 1 422 ? -28.480 38.421  72.325 1.00 62.09 ?  388  LYS B HD2  1 
ATOM   11584 H HD3  . LYS B 1 422 ? -28.248 38.340  70.755 1.00 62.09 ?  388  LYS B HD3  1 
ATOM   11585 H HE2  . LYS B 1 422 ? -25.970 38.457  71.029 1.00 45.49 ?  388  LYS B HE2  1 
ATOM   11586 H HE3  . LYS B 1 422 ? -26.132 38.750  72.583 1.00 45.49 ?  388  LYS B HE3  1 
ATOM   11587 H HZ1  . LYS B 1 422 ? -25.574 36.621  72.350 1.00 45.23 ?  388  LYS B HZ1  1 
ATOM   11588 H HZ2  . LYS B 1 422 ? -26.963 36.611  72.760 1.00 45.23 ?  388  LYS B HZ2  1 
ATOM   11589 H HZ3  . LYS B 1 422 ? -26.615 36.363  71.376 1.00 45.23 ?  388  LYS B HZ3  1 
HETATM 11590 C C5   . X6Y C 2 .   ? -5.297  34.636  44.476 1.00 11.51 ?  1    X6Y D C5   1 
HETATM 11591 C C6   . X6Y C 2 .   ? -5.758  35.963  44.980 1.00 11.13 ?  1    X6Y D C6   1 
HETATM 11592 C C2   . X6Y C 2 .   ? -3.396  33.382  42.777 1.00 12.11 ?  1    X6Y D C2   1 
HETATM 11593 C C4   . X6Y C 2 .   ? -5.567  34.450  42.998 1.00 11.17 ?  1    X6Y D C4   1 
HETATM 11594 C C3   . X6Y C 2 .   ? -4.850  33.209  42.516 1.00 10.78 ?  1    X6Y D C3   1 
HETATM 11595 C C1   . X6Y C 2 .   ? -3.179  33.441  44.265 1.00 11.93 ?  1    X6Y D C1   1 
HETATM 11596 O O5   . X6Y C 2 .   ? -3.869  34.605  44.788 1.00 12.28 ?  1    X6Y D O5   1 
HETATM 11597 O O4   . X6Y C 2 .   ? -5.128  35.545  42.213 1.00 11.88 ?  1    X6Y D O4   1 
HETATM 11598 O O1   . X6Y C 2 .   ? -3.645  32.277  44.869 1.00 12.03 ?  1    X6Y D O1   1 
HETATM 11599 O O3   . X6Y C 2 .   ? -5.106  32.991  41.083 1.00 11.91 ?  1    X6Y D O3   1 
HETATM 11600 S S1   . X6Y C 2 .   ? -1.200  32.430  41.656 1.00 11.90 ?  1    X6Y D S1   1 
HETATM 11601 O O6   . X6Y C 2 .   ? -0.279  32.529  42.777 1.00 12.49 ?  1    X6Y D O6   1 
HETATM 11602 O O7   . X6Y C 2 .   ? -1.207  33.630  40.836 1.00 12.67 -1 1    X6Y D O7   1 
HETATM 11603 O O8   . X6Y C 2 .   ? -1.002  31.179  40.903 1.00 12.40 ?  1    X6Y D O8   1 
HETATM 11604 O O2   . X6Y C 2 .   ? -2.679  32.242  42.249 1.00 11.28 ?  1    X6Y D O2   1 
HETATM 11605 H H5   . X6Y C 2 .   ? -5.850  33.844  44.961 1.00 13.81 ?  1    X6Y D H5   1 
HETATM 11606 H H61  . X6Y C 2 .   ? -5.672  35.989  46.064 1.00 13.36 ?  1    X6Y D H61  1 
HETATM 11607 H H63  . X6Y C 2 .   ? -5.141  36.748  44.550 1.00 13.36 ?  1    X6Y D H63  1 
HETATM 11608 H H62  . X6Y C 2 .   ? -6.795  36.119  44.695 1.00 13.36 ?  1    X6Y D H62  1 
HETATM 11609 H H2   . X6Y C 2 .   ? -3.017  34.274  42.284 1.00 14.53 ?  1    X6Y D H2   1 
HETATM 11610 H H4   . X6Y C 2 .   ? -6.637  34.396  42.858 1.00 13.40 ?  1    X6Y D H4   1 
HETATM 11611 H H3   . X6Y C 2 .   ? -5.223  32.323  43.013 1.00 12.93 ?  1    X6Y D H3   1 
HETATM 11612 H H1   . X6Y C 2 .   ? -2.107  33.490  44.504 1.00 14.32 ?  1    X6Y D H1   1 
HETATM 11613 H HO4  . X6Y C 2 .   ? -4.379  35.953  42.621 1.00 14.26 ?  1    X6Y D HO4  1 
HETATM 11614 H HO1  . X6Y C 2 .   ? -4.183  32.492  45.611 1.00 14.44 ?  1    X6Y D HO1  1 
HETATM 11615 C C5   . X2Y C 2 .   ? -4.410  30.276  40.170 1.00 13.26 ?  2    X2Y D C5   1 
HETATM 11616 C C4   . X2Y C 2 .   ? -5.063  30.195  38.818 1.00 13.60 ?  2    X2Y D C4   1 
HETATM 11617 C C3   . X2Y C 2 .   ? -5.618  31.536  38.427 1.00 12.45 ?  2    X2Y D C3   1 
HETATM 11618 C C2   . X2Y C 2 .   ? -6.622  32.017  39.480 1.00 11.93 ?  2    X2Y D C2   1 
HETATM 11619 C C1   . X2Y C 2 .   ? -6.042  31.964  40.890 1.00 12.25 ?  2    X2Y D C1   1 
HETATM 11620 O O5   . X2Y C 2 .   ? -5.436  30.680  41.173 1.00 12.57 ?  2    X2Y D O5   1 
HETATM 11621 C C6   . X2Y C 2 .   ? -3.832  29.000  40.697 1.00 13.83 ?  2    X2Y D C6   1 
HETATM 11622 O O3   . X2Y C 2 .   ? -6.329  31.425  37.169 1.00 12.78 ?  2    X2Y D O3   1 
HETATM 11623 S S1   . X2Y C 2 .   ? -8.539  33.770  39.524 1.00 14.55 ?  2    X2Y D S1   1 
HETATM 11624 O O6   . X2Y C 2 .   ? -8.743  33.477  40.966 1.00 16.11 ?  2    X2Y D O6   1 
HETATM 11625 O O7   . X2Y C 2 .   ? -9.428  32.892  38.730 1.00 15.84 -1 2    X2Y D O7   1 
HETATM 11626 O O8   . X2Y C 2 .   ? -8.596  35.156  39.148 1.00 14.80 ?  2    X2Y D O8   1 
HETATM 11627 O O2   . X2Y C 2 .   ? -6.992  33.363  39.144 1.00 12.58 ?  2    X2Y D O2   1 
HETATM 11628 S S2   . X2Y C 2 .   ? -6.266  27.955  37.942 1.00 18.68 ?  2    X2Y D S2   1 
HETATM 11629 O O9   . X2Y C 2 .   ? -7.085  28.399  36.774 1.00 19.90 ?  2    X2Y D O9   1 
HETATM 11630 O O10  . X2Y C 2 .   ? -4.855  27.621  37.596 1.00 24.17 -1 2    X2Y D O10  1 
HETATM 11631 O O11  . X2Y C 2 .   ? -7.037  27.052  38.828 1.00 27.42 ?  2    X2Y D O11  1 
HETATM 11632 O O4   . X2Y C 2 .   ? -6.155  29.264  38.929 1.00 13.57 ?  2    X2Y D O4   1 
HETATM 11633 H H5   . X2Y C 2 .   ? -3.567  30.957  40.043 1.00 15.91 ?  2    X2Y D H5   1 
HETATM 11634 H H4   . X2Y C 2 .   ? -4.357  29.854  38.061 1.00 16.32 ?  2    X2Y D H4   1 
HETATM 11635 H H3   . X2Y C 2 .   ? -4.802  32.239  38.312 1.00 14.95 ?  2    X2Y D H3   1 
HETATM 11636 H H2   . X2Y C 2 .   ? -7.499  31.398  39.467 1.00 14.32 ?  2    X2Y D H2   1 
HETATM 11637 H H1   . X2Y C 2 .   ? -6.851  32.139  41.594 1.00 14.70 ?  2    X2Y D H1   1 
HETATM 11638 H H61  . X2Y C 2 .   ? -3.037  28.664  40.038 1.00 16.59 ?  2    X2Y D H61  1 
HETATM 11639 H H63  . X2Y C 2 .   ? -3.430  29.168  41.692 1.00 16.59 ?  2    X2Y D H63  1 
HETATM 11640 H H62  . X2Y C 2 .   ? -4.609  28.243  40.743 1.00 16.59 ?  2    X2Y D H62  1 
HETATM 11641 C C1   . FUC C 2 .   ? -5.641  31.904  36.061 1.00 15.57 ?  3    FUC D C1   1 
HETATM 11642 C C2   . FUC C 2 .   ? -5.978  30.948  34.860 1.00 13.93 ?  3    FUC D C2   1 
HETATM 11643 C C3   . FUC C 2 .   ? -7.447  31.088  34.515 1.00 17.69 ?  3    FUC D C3   1 
HETATM 11644 C C4   . FUC C 2 .   ? -7.725  32.524  34.250 1.00 16.24 ?  3    FUC D C4   1 
HETATM 11645 C C5   . FUC C 2 .   ? -7.441  33.417  35.483 1.00 14.19 ?  3    FUC D C5   1 
HETATM 11646 C C6   . FUC C 2 .   ? -7.625  34.892  35.313 1.00 16.69 ?  3    FUC D C6   1 
HETATM 11647 O O2   . FUC C 2 .   ? -5.688  29.596  35.157 1.00 20.28 ?  3    FUC D O2   1 
HETATM 11648 O O3   . FUC C 2 .   ? -7.765  30.201  33.368 1.00 18.00 ?  3    FUC D O3   1 
HETATM 11649 O O4   . FUC C 2 .   ? -6.928  32.914  33.080 1.00 17.89 ?  3    FUC D O4   1 
HETATM 11650 O O5   . FUC C 2 .   ? -6.019  33.296  35.873 1.00 14.60 ?  3    FUC D O5   1 
HETATM 11651 H H1   . FUC C 2 .   ? -4.556  31.887  36.199 1.00 18.68 ?  3    FUC D H1   1 
HETATM 11652 H H2   . FUC C 2 .   ? -5.338  31.202  34.011 1.00 16.72 ?  3    FUC D H2   1 
HETATM 11653 H H3   . FUC C 2 .   ? -8.099  30.748  35.302 1.00 21.23 ?  3    FUC D H3   1 
HETATM 11654 H H4   . FUC C 2 .   ? -8.767  32.680  34.013 1.00 19.48 ?  3    FUC D H4   1 
HETATM 11655 H H5   . FUC C 2 .   ? -8.171  33.093  36.196 1.00 17.03 ?  3    FUC D H5   1 
HETATM 11656 H H61  . FUC C 2 .   ? -6.816  35.290  34.712 1.00 20.03 ?  3    FUC D H61  1 
HETATM 11657 H H62  . FUC C 2 .   ? -7.622  35.371  36.285 1.00 20.03 ?  3    FUC D H62  1 
HETATM 11658 H H63  . FUC C 2 .   ? -8.570  35.084  34.819 1.00 20.03 ?  3    FUC D H63  1 
HETATM 11659 H HO2  . FUC C 2 .   ? -6.075  29.355  35.999 1.00 24.33 ?  3    FUC D HO2  1 
HETATM 11660 H HO4  . FUC C 2 .   ? -6.942  32.201  32.463 1.00 21.47 ?  3    FUC D HO4  1 
HETATM 11661 C C5   . X6Y C 2 .   ? -9.168  27.763  33.995 1.00 17.63 ?  4    X6Y D C5   1 
HETATM 11662 C C6   . X6Y C 2 .   ? -9.833  26.981  35.060 1.00 24.71 ?  4    X6Y D C6   1 
HETATM 11663 C C2   . X6Y C 2 .   ? -9.358  29.459  31.762 1.00 21.74 ?  4    X6Y D C2   1 
HETATM 11664 C C4   . X6Y C 2 .   ? -9.396  27.193  32.601 1.00 20.18 ?  4    X6Y D C4   1 
HETATM 11665 C C3   . X6Y C 2 .   ? -8.829  28.090  31.580 1.00 17.79 ?  4    X6Y D C3   1 
HETATM 11666 C C1   . X6Y C 2 .   ? -9.168  30.017  33.178 1.00 14.85 ?  4    X6Y D C1   1 
HETATM 11667 O O5   . X6Y C 2 .   ? -9.724  29.130  34.134 1.00 22.63 ?  4    X6Y D O5   1 
HETATM 11668 O O4   . X6Y C 2 .   ? -10.840 27.005  32.351 1.00 26.25 ?  4    X6Y D O4   1 
HETATM 11669 O O3   . X6Y C 2 .   ? -9.217  27.649  30.224 1.00 23.20 ?  4    X6Y D O3   1 
HETATM 11670 S S1   . X6Y C 2 .   ? -9.603  31.438  30.086 1.00 23.66 ?  4    X6Y D S1   1 
HETATM 11671 O O6   . X6Y C 2 .   ? -10.602 30.772  29.190 1.00 29.08 ?  4    X6Y D O6   1 
HETATM 11672 O O7   . X6Y C 2 .   ? -10.266 32.364  31.086 1.00 36.96 -1 4    X6Y D O7   1 
HETATM 11673 O O8   . X6Y C 2 .   ? -8.602  32.141  29.231 1.00 22.42 ?  4    X6Y D O8   1 
HETATM 11674 O O2   . X6Y C 2 .   ? -8.673  30.313  30.859 1.00 18.20 ?  4    X6Y D O2   1 
HETATM 11675 H H5   . X6Y C 2 .   ? -8.089  27.721  34.137 1.00 21.16 ?  4    X6Y D H5   1 
HETATM 11676 H H61  . X6Y C 2 .   ? -10.901 27.124  34.999 1.00 29.65 ?  4    X6Y D H61  1 
HETATM 11677 H H63  . X6Y C 2 .   ? -9.603  25.933  34.934 1.00 29.65 ?  4    X6Y D H63  1 
HETATM 11678 H H62  . X6Y C 2 .   ? -9.480  27.313  36.025 1.00 29.65 ?  4    X6Y D H62  1 
HETATM 11679 H H2   . X6Y C 2 .   ? -10.426 29.437  31.551 1.00 26.09 ?  4    X6Y D H2   1 
HETATM 11680 H H4   . X6Y C 2 .   ? -8.933  26.214  32.534 1.00 24.22 ?  4    X6Y D H4   1 
HETATM 11681 H H3   . X6Y C 2 .   ? -7.739  28.060  31.656 1.00 21.35 ?  4    X6Y D H3   1 
HETATM 11682 H H1   . X6Y C 2 .   ? -9.647  30.979  33.313 1.00 17.81 ?  4    X6Y D H1   1 
HETATM 11683 H HO4  . X6Y C 2 .   ? -10.998 27.052  31.422 1.00 31.50 ?  4    X6Y D HO4  1 
HETATM 11684 H HO3  . X6Y C 2 .   ? -9.615  28.382  29.756 1.00 27.84 ?  4    X6Y D HO3  1 
HETATM 11685 C C5   . X6Y D 2 .   ? -11.355 14.787  28.475 1.00 11.15 ?  1    X6Y C C5   1 
HETATM 11686 C C6   . X6Y D 2 .   ? -10.738 13.705  27.618 1.00 11.56 ?  1    X6Y C C6   1 
HETATM 11687 C C2   . X6Y D 2 .   ? -12.749 17.285  28.383 1.00 10.27 ?  1    X6Y C C2   1 
HETATM 11688 C C4   . X6Y D 2 .   ? -10.598 16.104  28.373 1.00 11.03 ?  1    X6Y C C4   1 
HETATM 11689 C C3   . X6Y D 2 .   ? -11.414 17.171  29.047 1.00 10.53 ?  1    X6Y C C3   1 
HETATM 11690 C C1   . X6Y D 2 .   ? -13.462 15.963  28.592 1.00 11.46 ?  1    X6Y C C1   1 
HETATM 11691 O O5   . X6Y D 2 .   ? -12.709 14.898  27.963 1.00 11.13 ?  1    X6Y C O5   1 
HETATM 11692 O O4   . X6Y D 2 .   ? -10.395 16.512  27.022 1.00 10.79 ?  1    X6Y C O4   1 
HETATM 11693 O O1   . X6Y D 2 .   ? -13.633 15.753  29.932 1.00 11.20 ?  1    X6Y C O1   1 
HETATM 11694 O O3   . X6Y D 2 .   ? -10.703 18.473  28.993 1.00 10.82 ?  1    X6Y C O3   1 
HETATM 11695 S S1   . X6Y D 2 .   ? -14.501 19.216  28.031 1.00 11.07 ?  1    X6Y C S1   1 
HETATM 11696 O O6   . X6Y D 2 .   ? -15.717 18.401  27.817 1.00 12.46 ?  1    X6Y C O6   1 
HETATM 11697 O O7   . X6Y D 2 .   ? -14.760 20.387  28.863 1.00 11.29 ?  1    X6Y C O7   1 
HETATM 11698 O O8   . X6Y D 2 .   ? -13.824 19.477  26.801 1.00 12.19 ?  1    X6Y C O8   1 
HETATM 11699 O O2   . X6Y D 2 .   ? -13.496 18.360  28.979 1.00 10.97 ?  1    X6Y C O2   1 
HETATM 11700 H H5   . X6Y D 2 .   ? -11.312 14.515  29.520 1.00 13.38 ?  1    X6Y C H5   1 
HETATM 11701 H H61  . X6Y D 2 .   ? -9.734  13.488  27.976 1.00 13.87 ?  1    X6Y C H61  1 
HETATM 11702 H H63  . X6Y D 2 .   ? -10.689 14.044  26.587 1.00 13.87 ?  1    X6Y C H63  1 
HETATM 11703 H H62  . X6Y D 2 .   ? -11.345 12.806  27.676 1.00 13.87 ?  1    X6Y C H62  1 
HETATM 11704 H H2   . X6Y D 2 .   ? -12.664 17.529  27.327 1.00 12.33 ?  1    X6Y C H2   1 
HETATM 11705 H H4   . X6Y D 2 .   ? -9.616  15.972  28.805 1.00 13.23 ?  1    X6Y C H4   1 
HETATM 11706 H H3   . X6Y D 2 .   ? -11.542 16.933  30.094 1.00 12.64 ?  1    X6Y C H3   1 
HETATM 11707 H H1   . X6Y D 2 .   ? -14.472 15.976  28.159 1.00 13.75 ?  1    X6Y C H1   1 
HETATM 11708 H HO4  . X6Y D 2 .   ? -9.735  15.961  26.624 1.00 12.94 ?  1    X6Y C HO4  1 
HETATM 11709 H HO1  . X6Y D 2 .   ? -14.154 14.976  30.061 1.00 13.45 ?  1    X6Y C HO1  1 
HETATM 11710 C C5   . X2Y D 2 .   ? -11.785 20.444  30.860 1.00 13.15 ?  2    X2Y C C5   1 
HETATM 11711 C C4   . X2Y D 2 .   ? -10.746 21.528  30.828 1.00 13.40 ?  2    X2Y C C4   1 
HETATM 11712 C C3   . X2Y D 2 .   ? -9.688  21.227  29.820 1.00 12.52 ?  2    X2Y C C3   1 
HETATM 11713 C C2   . X2Y D 2 .   ? -9.044  19.879  30.091 1.00 12.69 ?  2    X2Y C C2   1 
HETATM 11714 C C1   . X2Y D 2 .   ? -10.124 18.772  30.239 1.00 12.81 ?  2    X2Y C C1   1 
HETATM 11715 O O5   . X2Y D 2 .   ? -11.127 19.143  31.195 1.00 12.19 ?  2    X2Y C O5   1 
HETATM 11716 C C6   . X2Y D 2 .   ? -12.879 20.683  31.868 1.00 13.98 ?  2    X2Y C C6   1 
HETATM 11717 O O3   . X2Y D 2 .   ? -8.604  22.181  29.921 1.00 13.20 ?  2    X2Y C O3   1 
HETATM 11718 S S1   . X2Y D 2 .   ? -6.890  18.574  29.416 1.00 12.91 ?  2    X2Y C S1   1 
HETATM 11719 O O6   . X2Y D 2 .   ? -6.115  19.363  30.346 1.00 13.75 ?  2    X2Y C O6   1 
HETATM 11720 O O7   . X2Y D 2 .   ? -6.278  18.382  28.137 1.00 13.49 ?  2    X2Y C O7   1 
HETATM 11721 O O8   . X2Y D 2 .   ? -7.423  17.390  30.074 1.00 13.57 ?  2    X2Y C O8   1 
HETATM 11722 O O2   . X2Y D 2 .   ? -8.180  19.506  29.003 1.00 11.50 ?  2    X2Y C O2   1 
HETATM 11723 S S2   . X2Y D 2 .   ? -10.067 22.914  33.065 1.00 20.13 ?  2    X2Y C S2   1 
HETATM 11724 O O9   . X2Y D 2 .   ? -11.206 23.758  32.601 1.00 25.96 ?  2    X2Y C O9   1 
HETATM 11725 O O10  . X2Y D 2 .   ? -10.096 22.330  34.413 1.00 25.12 ?  2    X2Y C O10  1 
HETATM 11726 O O11  . X2Y D 2 .   ? -8.830  23.626  32.593 1.00 20.93 ?  2    X2Y C O11  1 
HETATM 11727 O O4   . X2Y D 2 .   ? -10.117 21.504  32.150 1.00 13.98 ?  2    X2Y C O4   1 
HETATM 11728 H H5   . X2Y D 2 .   ? -12.280 20.438  29.888 1.00 15.77 ?  2    X2Y C H5   1 
HETATM 11729 H H4   . X2Y D 2 .   ? -11.191 22.497  30.603 1.00 16.07 ?  2    X2Y C H4   1 
HETATM 11730 H H3   . X2Y D 2 .   ? -10.151 21.279  28.842 1.00 15.03 ?  2    X2Y C H3   1 
HETATM 11731 H H2   . X2Y D 2 .   ? -8.452  19.960  30.984 1.00 15.22 ?  2    X2Y C H2   1 
HETATM 11732 H H1   . X2Y D 2 .   ? -9.643  17.858  30.577 1.00 15.37 ?  2    X2Y C H1   1 
HETATM 11733 H H61  . X2Y D 2 .   ? -13.751 20.092  31.603 1.00 16.78 ?  2    X2Y C H61  1 
HETATM 11734 H H63  . X2Y D 2 .   ? -12.531 20.393  32.855 1.00 16.78 ?  2    X2Y C H63  1 
HETATM 11735 H H62  . X2Y D 2 .   ? -13.144 21.737  31.872 1.00 16.78 ?  2    X2Y C H62  1 
HETATM 11736 C C1   . FUC D 2 .   ? -8.594  23.149  28.926 1.00 14.08 ?  3    FUC C C1   1 
HETATM 11737 C C2   . FUC D 2 .   ? -8.133  24.508  29.552 1.00 13.23 ?  3    FUC C C2   1 
HETATM 11738 C C3   . FUC D 2 .   ? -6.702  24.278  29.997 1.00 16.16 ?  3    FUC C C3   1 
HETATM 11739 C C4   . FUC D 2 .   ? -5.929  23.893  28.798 1.00 14.03 ?  3    FUC C C4   1 
HETATM 11740 C C5   . FUC D 2 .   ? -6.403  22.576  28.181 1.00 15.70 ?  3    FUC C C5   1 
HETATM 11741 C C6   . FUC D 2 .   ? -5.733  22.088  26.947 1.00 16.65 ?  3    FUC C C6   1 
HETATM 11742 O O2   . FUC D 2 .   ? -8.877  24.811  30.706 1.00 20.64 ?  3    FUC C O2   1 
HETATM 11743 O O3   . FUC D 2 .   ? -6.199  25.540  30.627 1.00 18.98 ?  3    FUC C O3   1 
HETATM 11744 O O4   . FUC D 2 .   ? -5.987  25.038  27.920 1.00 19.99 ?  3    FUC C O4   1 
HETATM 11745 O O5   . FUC D 2 .   ? -7.825  22.673  27.781 1.00 14.39 ?  3    FUC C O5   1 
HETATM 11746 H H1   . FUC D 2 .   ? -9.605  23.312  28.541 1.00 16.89 ?  3    FUC C H1   1 
HETATM 11747 H H2   . FUC D 2 .   ? -8.276  25.337  28.853 1.00 15.88 ?  3    FUC C H2   1 
HETATM 11748 H H3   . FUC D 2 .   ? -6.597  23.520  30.755 1.00 19.39 ?  3    FUC C H3   1 
HETATM 11749 H H4   . FUC D 2 .   ? -4.890  23.693  29.011 1.00 16.83 ?  3    FUC C H4   1 
HETATM 11750 H H5   . FUC D 2 .   ? -6.154  21.873  28.950 1.00 18.84 ?  3    FUC C H5   1 
HETATM 11751 H H61  . FUC D 2 .   ? -4.677  22.329  26.989 1.00 19.98 ?  3    FUC C H61  1 
HETATM 11752 H H62  . FUC D 2 .   ? -5.855  21.014  26.869 1.00 19.98 ?  3    FUC C H62  1 
HETATM 11753 H H63  . FUC D 2 .   ? -6.177  22.565  26.081 1.00 19.98 ?  3    FUC C H63  1 
HETATM 11754 H HO2  . FUC D 2 .   ? -9.744  25.127  30.438 1.00 24.77 ?  3    FUC C HO2  1 
HETATM 11755 H HO4  . FUC D 2 .   ? -5.753  24.736  27.051 1.00 23.99 ?  3    FUC C HO4  1 
HETATM 11756 C C5   . X6Y D 2 .   ? -5.871  25.544  33.533 1.00 15.54 ?  4    X6Y C C5   1 
HETATM 11757 C C6   . X6Y D 2 .   ? -6.019  24.691  34.751 1.00 28.78 ?  4    X6Y C C6   1 
HETATM 11758 C C2   . X6Y D 2 .   ? -4.395  26.816  31.572 1.00 23.84 ?  4    X6Y C C2   1 
HETATM 11759 C C4   . X6Y D 2 .   ? -5.329  26.949  33.793 1.00 20.02 ?  4    X6Y C C4   1 
HETATM 11760 C C3   . X6Y D 2 .   ? -5.181  27.640  32.527 1.00 15.95 ?  4    X6Y C C3   1 
HETATM 11761 C C1   . X6Y D 2 .   ? -4.912  25.384  31.280 1.00 12.80 ?  4    X6Y C C1   1 
HETATM 11762 O O5   . X6Y D 2 .   ? -5.094  24.728  32.540 1.00 21.38 ?  4    X6Y C O5   1 
HETATM 11763 O O4   . X6Y D 2 .   ? -4.031  26.911  34.467 1.00 31.76 ?  4    X6Y C O4   1 
HETATM 11764 O O3   . X6Y D 2 .   ? -4.397  28.872  32.804 1.00 25.35 ?  4    X6Y C O3   1 
HETATM 11765 S S1   . X6Y D 2 .   ? -3.011  27.525  29.543 1.00 24.31 ?  4    X6Y C S1   1 
HETATM 11766 O O6   . X6Y D 2 .   ? -1.915  28.223  30.326 1.00 29.42 ?  4    X6Y C O6   1 
HETATM 11767 O O7   . X6Y D 2 .   ? -2.708  26.081  29.192 1.00 29.35 ?  4    X6Y C O7   1 
HETATM 11768 O O8   . X6Y D 2 .   ? -3.239  28.355  28.318 1.00 26.30 ?  4    X6Y C O8   1 
HETATM 11769 O O2   . X6Y D 2 .   ? -4.432  27.532  30.368 1.00 18.88 ?  4    X6Y C O2   1 
HETATM 11770 H H5   . X6Y D 2 .   ? -6.866  25.768  33.152 1.00 18.64 ?  4    X6Y C H5   1 
HETATM 11771 H H61  . X6Y D 2 .   ? -6.643  23.840  34.522 1.00 34.54 ?  4    X6Y C H61  1 
HETATM 11772 H H63  . X6Y D 2 .   ? -6.476  25.268  35.542 1.00 34.54 ?  4    X6Y C H63  1 
HETATM 11773 H H62  . X6Y D 2 .   ? -5.047  24.349  35.073 1.00 34.54 ?  4    X6Y C H62  1 
HETATM 11774 H H2   . X6Y D 2 .   ? -3.401  26.679  31.992 1.00 28.61 ?  4    X6Y C H2   1 
HETATM 11775 H H4   . X6Y D 2 .   ? -6.004  27.472  34.462 1.00 24.02 ?  4    X6Y C H4   1 
HETATM 11776 H H3   . X6Y D 2 .   ? -6.157  27.880  32.098 1.00 19.14 ?  4    X6Y C H3   1 
HETATM 11777 H H1   . X6Y D 2 .   ? -4.256  24.809  30.639 1.00 15.36 ?  4    X6Y C H1   1 
HETATM 11778 H HO4  . X6Y D 2 .   ? -3.746  27.790  34.671 1.00 38.11 ?  4    X6Y C HO4  1 
HETATM 11779 H HO3  . X6Y D 2 .   ? -4.885  29.633  32.489 1.00 30.42 ?  4    X6Y C HO3  1 
HETATM 11780 O O    . HOH E 3 .   ? -26.597 -2.081  45.232 1.00 47.51 ?  401  HOH A O    1 
HETATM 11781 O O    . HOH E 3 .   ? 6.257   -3.522  43.123 1.00 42.31 ?  402  HOH A O    1 
HETATM 11782 O O    . HOH E 3 .   ? -4.244  8.511   8.335  1.00 7.89  ?  403  HOH A O    1 
HETATM 11783 O O    . HOH E 3 .   ? 9.841   17.628  43.060 1.00 45.29 ?  404  HOH A O    1 
HETATM 11784 O O    . HOH E 3 .   ? -24.487 35.293  14.887 1.00 42.41 ?  405  HOH A O    1 
HETATM 11785 O O    . HOH E 3 .   ? -10.304 9.938   42.438 1.00 41.51 ?  406  HOH A O    1 
HETATM 11786 O O    . HOH E 3 .   ? -28.700 5.252   33.190 1.00 11.37 ?  407  HOH A O    1 
HETATM 11787 O O    . HOH E 3 .   ? -16.363 4.529   3.891  1.00 28.26 ?  408  HOH A O    1 
HETATM 11788 O O    . HOH E 3 .   ? -31.917 8.735   26.887 1.00 31.84 ?  409  HOH A O    1 
HETATM 11789 O O    . HOH E 3 .   ? -10.288 37.853  10.554 1.00 39.62 ?  410  HOH A O    1 
HETATM 11790 O O    . HOH E 3 .   ? 6.633   -0.637  43.468 1.00 38.52 ?  411  HOH A O    1 
HETATM 11791 O O    . HOH E 3 .   ? 4.502   -1.679  25.233 1.00 40.25 ?  412  HOH A O    1 
HETATM 11792 O O    . HOH E 3 .   ? -12.076 -12.519 27.903 1.00 32.09 ?  413  HOH A O    1 
HETATM 11793 O O    . HOH E 3 .   ? -28.819 34.541  17.274 1.00 41.39 ?  414  HOH A O    1 
HETATM 11794 O O    . HOH E 3 .   ? -0.162  -8.091  15.185 1.00 44.16 ?  415  HOH A O    1 
HETATM 11795 O O    . HOH E 3 .   ? -12.259 5.459   43.400 1.00 27.01 ?  416  HOH A O    1 
HETATM 11796 O O    . HOH E 3 .   ? -3.997  20.839  49.692 1.00 42.27 ?  417  HOH A O    1 
HETATM 11797 O O    . HOH E 3 .   ? -12.719 -2.029  8.599  1.00 38.79 ?  418  HOH A O    1 
HETATM 11798 O O    . HOH E 3 .   ? 8.881   16.688  30.029 1.00 29.81 ?  419  HOH A O    1 
HETATM 11799 O O    . HOH E 3 .   ? -13.924 -0.230  10.003 1.00 26.28 ?  420  HOH A O    1 
HETATM 11800 O O    . HOH E 3 .   ? -28.553 6.979   11.866 1.00 40.28 ?  421  HOH A O    1 
HETATM 11801 O O    . HOH E 3 .   ? -1.281  -13.676 25.852 1.00 41.26 ?  422  HOH A O    1 
HETATM 11802 O O    . HOH E 3 .   ? -13.591 -9.164  20.592 1.00 26.06 ?  423  HOH A O    1 
HETATM 11803 O O    . HOH E 3 .   ? -30.223 36.348  28.155 1.00 44.01 ?  424  HOH A O    1 
HETATM 11804 O O    . HOH E 3 .   ? -10.455 15.099  3.645  1.00 34.19 ?  425  HOH A O    1 
HETATM 11805 O O    . HOH E 3 .   ? 4.757   -0.667  31.303 1.00 30.00 ?  426  HOH A O    1 
HETATM 11806 O O    . HOH E 3 .   ? -30.360 0.774   16.868 1.00 44.47 ?  427  HOH A O    1 
HETATM 11807 O O    . HOH E 3 .   ? 2.178   24.351  7.963  1.00 43.86 ?  428  HOH A O    1 
HETATM 11808 O O    . HOH E 3 .   ? 18.562  12.822  21.572 1.00 28.69 ?  429  HOH A O    1 
HETATM 11809 O O    . HOH E 3 .   ? -27.564 9.188   12.383 1.00 22.71 ?  430  HOH A O    1 
HETATM 11810 O O    . HOH E 3 .   ? 7.896   0.123   38.501 1.00 39.17 ?  431  HOH A O    1 
HETATM 11811 O O    . HOH E 3 .   ? -2.258  2.853   33.280 1.00 28.76 ?  432  HOH A O    1 
HETATM 11812 O O    . HOH E 3 .   ? -19.241 34.442  7.611  1.00 23.16 ?  433  HOH A O    1 
HETATM 11813 O O    . HOH E 3 .   ? -28.041 -2.508  27.380 1.00 45.36 ?  434  HOH A O    1 
HETATM 11814 O O    . HOH E 3 .   ? -21.949 -10.054 26.472 1.00 33.01 ?  435  HOH A O    1 
HETATM 11815 O O    . HOH E 3 .   ? 1.278   -16.419 43.617 1.00 41.00 ?  436  HOH A O    1 
HETATM 11816 O O    . HOH E 3 .   ? -30.018 3.727   38.206 1.00 36.53 ?  437  HOH A O    1 
HETATM 11817 O O    . HOH E 3 .   ? -5.883  -17.830 37.668 1.00 26.51 ?  438  HOH A O    1 
HETATM 11818 O O    . HOH E 3 .   ? -28.111 7.851   16.445 1.00 23.93 ?  439  HOH A O    1 
HETATM 11819 O O    . HOH E 3 .   ? -20.046 -3.073  16.336 1.00 39.81 ?  440  HOH A O    1 
HETATM 11820 O O    . HOH E 3 .   ? -14.516 12.822  38.214 1.00 37.76 ?  441  HOH A O    1 
HETATM 11821 O O    . HOH E 3 .   ? -6.528  36.249  9.468  1.00 39.22 ?  442  HOH A O    1 
HETATM 11822 O O    . HOH E 3 .   ? -2.266  -4.759  13.228 1.00 40.88 ?  443  HOH A O    1 
HETATM 11823 O O    . HOH E 3 .   ? 7.143   11.091  39.618 1.00 32.44 ?  444  HOH A O    1 
HETATM 11824 O O    . HOH E 3 .   ? -20.722 -6.385  18.313 1.00 30.40 ?  445  HOH A O    1 
HETATM 11825 O O    . HOH E 3 .   ? 10.035  5.285   30.930 1.00 34.68 ?  446  HOH A O    1 
HETATM 11826 O O    . HOH E 3 .   ? -33.861 19.885  29.049 1.00 25.38 ?  447  HOH A O    1 
HETATM 11827 O O    . HOH E 3 .   ? -4.332  -4.892  14.806 1.00 33.68 ?  448  HOH A O    1 
HETATM 11828 O O    . HOH E 3 .   ? -30.020 8.129   43.574 1.00 35.88 ?  449  HOH A O    1 
HETATM 11829 O O    . HOH E 3 .   ? -8.240  21.384  6.393  1.00 22.49 ?  450  HOH A O    1 
HETATM 11830 O O    . HOH E 3 .   ? -10.736 -1.032  6.423  1.00 31.40 ?  451  HOH A O    1 
HETATM 11831 O O    . HOH E 3 .   ? 6.581   6.097   50.636 1.00 35.64 ?  452  HOH A O    1 
HETATM 11832 O O    . HOH E 3 .   ? -1.309  25.834  27.078 1.00 27.88 ?  453  HOH A O    1 
HETATM 11833 O O    . HOH E 3 .   ? -14.443 0.783   4.841  1.00 27.51 ?  454  HOH A O    1 
HETATM 11834 O O    . HOH E 3 .   ? 0.866   0.706   11.024 1.00 40.38 ?  455  HOH A O    1 
HETATM 11835 O O    . HOH E 3 .   ? -6.781  17.970  18.933 1.00 12.22 ?  456  HOH A O    1 
HETATM 11836 O O    . HOH E 3 .   ? -5.457  -6.377  16.465 1.00 21.59 ?  457  HOH A O    1 
HETATM 11837 O O    . HOH E 3 .   ? -17.365 2.598   47.473 1.00 34.42 ?  458  HOH A O    1 
HETATM 11838 O O    . HOH E 3 .   ? -24.999 38.726  19.479 1.00 46.42 ?  459  HOH A O    1 
HETATM 11839 O O    . HOH E 3 .   ? -28.756 9.389   47.965 1.00 40.24 ?  460  HOH A O    1 
HETATM 11840 O O    . HOH E 3 .   ? -8.994  2.646   47.379 1.00 40.64 ?  461  HOH A O    1 
HETATM 11841 O O    . HOH E 3 .   ? -30.067 16.423  33.203 1.00 22.99 ?  462  HOH A O    1 
HETATM 11842 O O    . HOH E 3 .   ? -35.776 26.561  17.436 1.00 19.24 ?  463  HOH A O    1 
HETATM 11843 O O    . HOH E 3 .   ? -21.807 1.113   49.676 1.00 45.01 ?  464  HOH A O    1 
HETATM 11844 O O    . HOH E 3 .   ? -21.785 -2.553  21.308 1.00 35.52 ?  465  HOH A O    1 
HETATM 11845 O O    . HOH E 3 .   ? -21.212 -9.721  48.740 1.00 36.50 ?  466  HOH A O    1 
HETATM 11846 O O    . HOH E 3 .   ? -0.809  11.345  33.819 1.00 12.37 ?  467  HOH A O    1 
HETATM 11847 O O    . HOH E 3 .   ? -6.700  23.613  23.667 1.00 16.24 ?  468  HOH A O    1 
HETATM 11848 O O    . HOH E 3 .   ? -30.805 10.676  22.721 1.00 29.47 ?  469  HOH A O    1 
HETATM 11849 O O    . HOH E 3 .   ? 3.395   -2.010  23.310 1.00 35.13 ?  470  HOH A O    1 
HETATM 11850 O O    . HOH E 3 .   ? -8.446  20.104  13.271 1.00 13.86 ?  471  HOH A O    1 
HETATM 11851 O O    . HOH E 3 .   ? 9.938   24.646  21.841 1.00 26.22 ?  472  HOH A O    1 
HETATM 11852 O O    . HOH E 3 .   ? 10.329  21.797  26.075 1.00 27.21 ?  473  HOH A O    1 
HETATM 11853 O O    . HOH E 3 .   ? 3.317   21.517  33.316 1.00 14.61 ?  474  HOH A O    1 
HETATM 11854 O O    . HOH E 3 .   ? -21.758 10.361  35.569 1.00 16.74 ?  475  HOH A O    1 
HETATM 11855 O O    . HOH E 3 .   ? -30.727 13.035  24.338 1.00 22.76 ?  476  HOH A O    1 
HETATM 11856 O O    . HOH E 3 .   ? 2.180   23.092  50.860 1.00 23.61 ?  477  HOH A O    1 
HETATM 11857 O O    . HOH E 3 .   ? -30.348 32.994  18.786 1.00 32.43 ?  478  HOH A O    1 
HETATM 11858 O O    . HOH E 3 .   ? -23.773 10.399  45.650 1.00 40.69 ?  479  HOH A O    1 
HETATM 11859 O O    . HOH E 3 .   ? -11.074 29.574  17.828 1.00 17.73 ?  480  HOH A O    1 
HETATM 11860 O O    . HOH E 3 .   ? 0.748   -6.708  33.739 1.00 17.67 ?  481  HOH A O    1 
HETATM 11861 O O    . HOH E 3 .   ? -20.543 0.507   15.070 1.00 23.49 ?  482  HOH A O    1 
HETATM 11862 O O    . HOH E 3 .   ? -5.208  9.246   3.267  1.00 27.16 ?  483  HOH A O    1 
HETATM 11863 O O    . HOH E 3 .   ? -15.626 36.360  6.278  1.00 42.56 ?  484  HOH A O    1 
HETATM 11864 O O    . HOH E 3 .   ? -0.302  -17.557 30.234 1.00 45.51 ?  485  HOH A O    1 
HETATM 11865 O O    . HOH E 3 .   ? -15.921 -8.592  30.542 1.00 17.93 ?  486  HOH A O    1 
HETATM 11866 O O    . HOH E 3 .   ? -5.316  -21.188 28.996 1.00 37.79 ?  487  HOH A O    1 
HETATM 11867 O O    . HOH E 3 .   ? 0.474   7.065   49.864 1.00 42.25 ?  488  HOH A O    1 
HETATM 11868 O O    . HOH E 3 .   ? 2.175   -3.898  29.991 1.00 18.13 ?  489  HOH A O    1 
HETATM 11869 O O    . HOH E 3 .   ? -24.882 31.188  15.211 1.00 22.67 ?  490  HOH A O    1 
HETATM 11870 O O    . HOH E 3 .   ? -24.294 20.378  4.695  1.00 18.08 ?  491  HOH A O    1 
HETATM 11871 O O    . HOH E 3 .   ? -0.975  11.973  29.928 1.00 15.66 ?  492  HOH A O    1 
HETATM 11872 O O    . HOH E 3 .   ? 0.381   -3.878  46.072 1.00 27.24 ?  493  HOH A O    1 
HETATM 11873 O O    . HOH E 3 .   ? -19.722 -10.704 35.263 1.00 34.25 ?  494  HOH A O    1 
HETATM 11874 O O    . HOH E 3 .   ? -0.856  5.674   10.327 1.00 28.99 ?  495  HOH A O    1 
HETATM 11875 O O    . HOH E 3 .   ? 0.069   4.998   34.834 1.00 24.53 ?  496  HOH A O    1 
HETATM 11876 O O    . HOH E 3 .   ? -21.396 -6.839  36.294 1.00 30.98 ?  497  HOH A O    1 
HETATM 11877 O O    . HOH E 3 .   ? -11.761 14.579  32.606 1.00 15.73 ?  498  HOH A O    1 
HETATM 11878 O O    . HOH E 3 .   ? 10.204  15.315  19.217 1.00 22.38 ?  499  HOH A O    1 
HETATM 11879 O O    . HOH E 3 .   ? -34.470 19.421  24.131 1.00 15.63 ?  500  HOH A O    1 
HETATM 11880 O O    . HOH E 3 .   ? -13.040 8.817   3.479  1.00 31.95 ?  501  HOH A O    1 
HETATM 11881 O O    . HOH E 3 .   ? -0.724  -5.823  26.697 1.00 17.25 ?  502  HOH A O    1 
HETATM 11882 O O    . HOH E 3 .   ? -1.151  -10.235 20.023 1.00 28.61 ?  503  HOH A O    1 
HETATM 11883 O O    . HOH E 3 .   ? -22.133 -7.556  24.861 1.00 24.28 ?  504  HOH A O    1 
HETATM 11884 O O    . HOH E 3 .   ? -19.550 12.172  37.990 1.00 30.68 ?  505  HOH A O    1 
HETATM 11885 O O    . HOH E 3 .   ? -5.776  22.993  20.397 1.00 11.95 ?  506  HOH A O    1 
HETATM 11886 O O    . HOH E 3 .   ? -6.426  -11.889 44.574 1.00 24.40 ?  507  HOH A O    1 
HETATM 11887 O O    . HOH E 3 .   ? -18.766 35.598  29.779 1.00 32.31 ?  508  HOH A O    1 
HETATM 11888 O O    . HOH E 3 .   ? -3.407  -20.603 35.128 1.00 34.48 ?  509  HOH A O    1 
HETATM 11889 O O    . HOH E 3 .   ? -11.719 24.799  18.812 1.00 11.84 ?  510  HOH A O    1 
HETATM 11890 O O    . HOH E 3 .   ? -0.478  21.316  26.220 1.00 14.53 ?  511  HOH A O    1 
HETATM 11891 O O    . HOH E 3 .   ? -5.116  15.562  4.533  1.00 21.28 ?  512  HOH A O    1 
HETATM 11892 O O    . HOH E 3 .   ? 9.328   2.728   22.095 1.00 23.55 ?  513  HOH A O    1 
HETATM 11893 O O    . HOH E 3 .   ? -28.820 27.518  13.221 1.00 16.49 ?  514  HOH A O    1 
HETATM 11894 O O    . HOH E 3 .   ? -1.490  7.046   48.153 1.00 43.64 ?  515  HOH A O    1 
HETATM 11895 O O    . HOH E 3 .   ? -17.644 36.496  28.214 1.00 31.42 ?  516  HOH A O    1 
HETATM 11896 O O    . HOH E 3 .   ? -8.479  22.893  13.145 1.00 12.36 ?  517  HOH A O    1 
HETATM 11897 O O    . HOH E 3 .   ? 11.922  13.243  18.651 1.00 24.56 ?  518  HOH A O    1 
HETATM 11898 O O    . HOH E 3 .   ? -22.447 -3.628  9.558  1.00 40.42 ?  519  HOH A O    1 
HETATM 11899 O O    . HOH E 3 .   ? -4.432  14.576  38.754 1.00 24.21 ?  520  HOH A O    1 
HETATM 11900 O O    . HOH E 3 .   ? -17.458 3.464   13.466 1.00 23.19 ?  521  HOH A O    1 
HETATM 11901 O O    . HOH E 3 .   ? -7.560  19.592  10.655 1.00 15.19 ?  522  HOH A O    1 
HETATM 11902 O O    . HOH E 3 .   ? -18.051 13.171  4.901  1.00 20.83 ?  523  HOH A O    1 
HETATM 11903 O O    . HOH E 3 .   ? -11.925 32.821  32.936 1.00 15.61 ?  524  HOH A O    1 
HETATM 11904 O O    . HOH E 3 .   ? -27.504 19.207  25.841 1.00 12.91 ?  525  HOH A O    1 
HETATM 11905 O O    . HOH E 3 .   ? -4.332  3.411   49.157 1.00 39.06 ?  526  HOH A O    1 
HETATM 11906 O O    . HOH E 3 .   ? -30.793 25.519  15.048 1.00 16.91 ?  527  HOH A O    1 
HETATM 11907 O O    . HOH E 3 .   ? -5.926  -6.008  13.367 1.00 26.22 ?  528  HOH A O    1 
HETATM 11908 O O    . HOH E 3 .   ? -0.094  -7.876  44.606 1.00 27.24 ?  529  HOH A O    1 
HETATM 11909 O O    . HOH E 3 .   ? 6.273   1.946   40.886 1.00 31.56 ?  530  HOH A O    1 
HETATM 11910 O O    . HOH E 3 .   ? -10.861 -5.339  52.262 1.00 38.07 ?  531  HOH A O    1 
HETATM 11911 O O    . HOH E 3 .   ? -0.991  -0.700  18.293 1.00 14.47 ?  532  HOH A O    1 
HETATM 11912 O O    . HOH E 3 .   ? 10.975  19.659  15.610 1.00 29.10 ?  533  HOH A O    1 
HETATM 11913 O O    . HOH E 3 .   ? -13.724 31.840  19.893 1.00 19.69 ?  534  HOH A O    1 
HETATM 11914 O O    . HOH E 3 .   ? 6.904   -2.155  13.285 1.00 51.18 ?  535  HOH A O    1 
HETATM 11915 O O    . HOH E 3 .   ? 0.169   12.329  9.964  1.00 14.81 ?  536  HOH A O    1 
HETATM 11916 O O    . HOH E 3 .   ? -33.704 8.136   31.286 1.00 41.16 ?  537  HOH A O    1 
HETATM 11917 O O    . HOH E 3 .   ? -12.576 7.810   35.507 1.00 14.69 ?  538  HOH A O    1 
HETATM 11918 O O    . HOH E 3 .   ? -17.033 18.939  4.899  1.00 16.72 ?  539  HOH A O    1 
HETATM 11919 O O    . HOH E 3 .   ? 7.061   -7.152  31.301 1.00 33.62 ?  540  HOH A O    1 
HETATM 11920 O O    . HOH E 3 .   ? -21.902 -4.742  37.748 1.00 23.36 ?  541  HOH A O    1 
HETATM 11921 O O    . HOH E 3 .   ? -14.183 3.556   44.148 1.00 28.41 ?  542  HOH A O    1 
HETATM 11922 O O    . HOH E 3 .   ? -33.073 15.856  18.290 1.00 23.07 ?  543  HOH A O    1 
HETATM 11923 O O    . HOH E 3 .   ? -25.951 4.461   18.557 1.00 23.09 ?  544  HOH A O    1 
HETATM 11924 O O    . HOH E 3 .   ? -17.572 37.836  8.412  1.00 38.92 ?  545  HOH A O    1 
HETATM 11925 O O    . HOH E 3 .   ? -26.584 30.122  17.554 1.00 17.25 ?  546  HOH A O    1 
HETATM 11926 O O    . HOH E 3 .   ? 1.549   26.311  13.265 1.00 16.96 ?  547  HOH A O    1 
HETATM 11927 O O    . HOH E 3 .   ? -15.215 36.009  15.663 1.00 19.35 ?  548  HOH A O    1 
HETATM 11928 O O    . HOH E 3 .   ? 13.353  8.819   19.916 1.00 34.81 ?  549  HOH A O    1 
HETATM 11929 O O    . HOH E 3 .   ? -0.000  -5.977  42.721 1.00 19.40 ?  550  HOH A O    1 
HETATM 11930 O O    . HOH E 3 .   ? 12.897  13.340  28.460 1.00 18.77 ?  551  HOH A O    1 
HETATM 11931 O O    . HOH E 3 .   ? -1.750  9.694   4.203  1.00 28.46 ?  552  HOH A O    1 
HETATM 11932 O O    . HOH E 3 .   ? -4.344  4.640   9.472  1.00 18.14 ?  553  HOH A O    1 
HETATM 11933 O O    . HOH E 3 .   ? -11.057 -1.871  12.054 1.00 21.53 ?  554  HOH A O    1 
HETATM 11934 O O    . HOH E 3 .   ? -6.440  -16.487 44.425 1.00 42.93 ?  555  HOH A O    1 
HETATM 11935 O O    . HOH E 3 .   ? -20.056 -14.556 35.989 1.00 34.81 ?  556  HOH A O    1 
HETATM 11936 O O    . HOH E 3 .   ? -20.912 29.982  22.061 1.00 13.09 ?  557  HOH A O    1 
HETATM 11937 O O    . HOH E 3 .   ? -10.248 10.225  33.971 1.00 15.02 ?  558  HOH A O    1 
HETATM 11938 O O    . HOH E 3 .   ? -13.585 -7.604  22.761 1.00 17.08 ?  559  HOH A O    1 
HETATM 11939 O O    . HOH E 3 .   ? 3.602   20.384  8.120  1.00 29.34 ?  560  HOH A O    1 
HETATM 11940 O O    . HOH E 3 .   ? 9.720   10.800  47.342 1.00 46.70 ?  561  HOH A O    1 
HETATM 11941 O O    . HOH E 3 .   ? -25.037 1.368   20.024 1.00 34.97 ?  562  HOH A O    1 
HETATM 11942 O O    . HOH E 3 .   ? 10.755  20.505  23.738 1.00 33.58 ?  563  HOH A O    1 
HETATM 11943 O O    . HOH E 3 .   ? -12.110 22.336  19.998 1.00 12.26 ?  564  HOH A O    1 
HETATM 11944 O O    . HOH E 3 .   ? 2.283   -13.013 37.095 1.00 23.92 ?  565  HOH A O    1 
HETATM 11945 O O    . HOH E 3 .   ? -1.725  2.149   11.439 1.00 21.58 ?  566  HOH A O    1 
HETATM 11946 O O    . HOH E 3 .   ? 4.515   14.212  43.314 1.00 47.47 ?  567  HOH A O    1 
HETATM 11947 O O    . HOH E 3 .   ? -8.929  -9.673  16.919 1.00 16.62 ?  568  HOH A O    1 
HETATM 11948 O O    . HOH E 3 .   ? -28.541 2.210   12.176 1.00 31.81 ?  569  HOH A O    1 
HETATM 11949 O O    . HOH E 3 .   ? 3.135   3.390   32.045 1.00 22.89 ?  570  HOH A O    1 
HETATM 11950 O O    . HOH E 3 .   ? -1.984  29.960  47.254 1.00 13.20 ?  571  HOH A O    1 
HETATM 11951 O O    . HOH E 3 .   ? -19.209 4.098   36.520 1.00 15.21 ?  572  HOH A O    1 
HETATM 11952 O O    . HOH E 3 .   ? -16.673 15.933  27.103 1.00 12.17 ?  573  HOH A O    1 
HETATM 11953 O O    . HOH E 3 .   ? -15.560 -1.559  15.670 1.00 21.81 ?  574  HOH A O    1 
HETATM 11954 O O    . HOH E 3 .   ? 12.381  17.576  21.458 1.00 35.04 ?  575  HOH A O    1 
HETATM 11955 O O    . HOH E 3 .   ? 1.112   -2.202  48.173 1.00 30.52 ?  576  HOH A O    1 
HETATM 11956 O O    . HOH E 3 .   ? -20.357 35.015  10.067 1.00 18.78 ?  577  HOH A O    1 
HETATM 11957 O O    . HOH E 3 .   ? -17.761 -3.804  9.106  1.00 38.07 ?  578  HOH A O    1 
HETATM 11958 O O    . HOH E 3 .   ? -27.951 31.532  28.251 1.00 22.21 ?  579  HOH A O    1 
HETATM 11959 O O    . HOH E 3 .   ? 3.006   0.597   20.313 1.00 30.82 ?  580  HOH A O    1 
HETATM 11960 O O    . HOH E 3 .   ? -22.515 -14.695 42.750 1.00 42.31 ?  581  HOH A O    1 
HETATM 11961 O O    . HOH E 3 .   ? -17.952 37.572  25.788 1.00 28.78 ?  582  HOH A O    1 
HETATM 11962 O O    . HOH E 3 .   ? 8.572   15.207  14.249 1.00 24.17 ?  583  HOH A O    1 
HETATM 11963 O O    . HOH E 3 .   ? -23.865 16.660  8.892  1.00 19.20 ?  584  HOH A O    1 
HETATM 11964 O O    . HOH E 3 .   ? 4.709   -0.370  41.281 1.00 22.55 ?  585  HOH A O    1 
HETATM 11965 O O    . HOH E 3 .   ? -25.363 -4.625  42.882 1.00 34.43 ?  586  HOH A O    1 
HETATM 11966 O O    . HOH E 3 .   ? -5.084  31.378  13.089 1.00 20.61 ?  587  HOH A O    1 
HETATM 11967 O O    . HOH E 3 .   ? -20.938 26.844  31.297 1.00 17.19 ?  588  HOH A O    1 
HETATM 11968 O O    . HOH E 3 .   ? -18.062 -1.106  16.056 1.00 33.07 ?  589  HOH A O    1 
HETATM 11969 O O    . HOH E 3 .   ? 0.968   5.615   6.826  1.00 35.66 ?  590  HOH A O    1 
HETATM 11970 O O    . HOH E 3 .   ? -11.532 5.838   6.286  1.00 16.08 ?  591  HOH A O    1 
HETATM 11971 O O    . HOH E 3 .   ? -12.922 9.813   41.189 1.00 33.06 ?  592  HOH A O    1 
HETATM 11972 O O    . HOH E 3 .   ? 4.273   19.997  11.798 1.00 18.22 ?  593  HOH A O    1 
HETATM 11973 O O    . HOH E 3 .   ? -8.456  8.638   6.330  1.00 16.26 ?  594  HOH A O    1 
HETATM 11974 O O    . HOH E 3 .   ? -23.813 33.908  28.145 1.00 25.14 ?  595  HOH A O    1 
HETATM 11975 O O    . HOH E 3 .   ? 10.859  19.063  27.837 1.00 27.69 ?  596  HOH A O    1 
HETATM 11976 O O    . HOH E 3 .   ? -12.443 -20.431 34.708 1.00 35.86 ?  597  HOH A O    1 
HETATM 11977 O O    . HOH E 3 .   ? -13.076 16.351  3.947  1.00 27.45 ?  598  HOH A O    1 
HETATM 11978 O O    . HOH E 3 .   ? -2.179  28.719  16.487 1.00 32.27 ?  599  HOH A O    1 
HETATM 11979 O O    . HOH E 3 .   ? -18.273 12.382  43.021 1.00 32.61 ?  600  HOH A O    1 
HETATM 11980 O O    . HOH E 3 .   ? -34.199 26.902  22.044 1.00 15.58 ?  601  HOH A O    1 
HETATM 11981 O O    . HOH E 3 .   ? -6.037  2.234   12.435 1.00 16.68 ?  602  HOH A O    1 
HETATM 11982 O O    . HOH E 3 .   ? -1.362  3.580   30.610 1.00 14.99 ?  603  HOH A O    1 
HETATM 11983 O O    . HOH E 3 .   ? 13.656  11.843  32.195 1.00 35.64 ?  604  HOH A O    1 
HETATM 11984 O O    . HOH E 3 .   ? -12.667 -4.315  24.748 1.00 14.36 ?  605  HOH A O    1 
HETATM 11985 O O    . HOH E 3 .   ? -23.376 28.842  29.588 1.00 29.36 ?  606  HOH A O    1 
HETATM 11986 O O    . HOH E 3 .   ? -1.114  16.467  34.261 1.00 14.69 ?  607  HOH A O    1 
HETATM 11987 O O    . HOH E 3 .   ? -22.983 6.342   8.394  1.00 22.18 ?  608  HOH A O    1 
HETATM 11988 O O    . HOH E 3 .   ? -4.482  19.161  48.109 1.00 35.95 ?  609  HOH A O    1 
HETATM 11989 O O    . HOH E 3 .   ? -28.515 5.112   35.588 1.00 19.93 ?  610  HOH A O    1 
HETATM 11990 O O    . HOH E 3 .   ? -16.336 33.641  5.004  1.00 29.12 ?  611  HOH A O    1 
HETATM 11991 O O    . HOH E 3 .   ? -3.105  -16.447 41.558 1.00 43.90 ?  612  HOH A O    1 
HETATM 11992 O O    . HOH E 3 .   ? 1.185   20.667  40.147 1.00 32.25 ?  613  HOH A O    1 
HETATM 11993 O O    . HOH E 3 .   ? -10.799 33.799  16.316 1.00 19.30 ?  614  HOH A O    1 
HETATM 11994 O O    . HOH E 3 .   ? -14.468 3.446   11.893 1.00 18.70 ?  615  HOH A O    1 
HETATM 11995 O O    . HOH E 3 .   ? -18.472 -11.895 23.572 1.00 24.73 ?  616  HOH A O    1 
HETATM 11996 O O    . HOH E 3 .   ? -33.193 15.995  22.847 1.00 21.29 ?  617  HOH A O    1 
HETATM 11997 O O    . HOH E 3 .   ? -6.829  2.795   6.272  1.00 30.33 ?  618  HOH A O    1 
HETATM 11998 O O    . HOH E 3 .   ? 2.567   13.636  10.412 1.00 14.43 ?  619  HOH A O    1 
HETATM 11999 O O    . HOH E 3 .   ? -10.012 10.960  6.457  1.00 16.75 ?  620  HOH A O    1 
HETATM 12000 O O    . HOH E 3 .   ? -12.003 0.560   10.997 1.00 18.88 ?  621  HOH A O    1 
HETATM 12001 O O    . HOH E 3 .   ? 7.714   18.586  34.226 1.00 30.71 ?  622  HOH A O    1 
HETATM 12002 O O    . HOH E 3 .   ? 9.395   12.827  12.692 1.00 22.94 ?  623  HOH A O    1 
HETATM 12003 O O    . HOH E 3 .   ? 8.219   16.360  17.581 1.00 19.43 ?  624  HOH A O    1 
HETATM 12004 O O    . HOH E 3 .   ? 4.014   21.547  28.813 1.00 13.39 ?  625  HOH A O    1 
HETATM 12005 O O    . HOH E 3 .   ? -4.748  -3.956  8.579  1.00 42.05 ?  626  HOH A O    1 
HETATM 12006 O O    . HOH E 3 .   ? 0.473   32.505  47.476 1.00 13.29 ?  627  HOH A O    1 
HETATM 12007 O O    . HOH E 3 .   ? -0.207  26.902  49.372 1.00 15.26 ?  628  HOH A O    1 
HETATM 12008 O O    . HOH E 3 .   ? 1.977   6.681   32.946 1.00 35.40 ?  629  HOH A O    1 
HETATM 12009 O O    . HOH E 3 .   ? -15.118 38.684  10.323 1.00 36.29 ?  630  HOH A O    1 
HETATM 12010 O O    . HOH E 3 .   ? -30.468 7.391   26.161 1.00 34.53 ?  631  HOH A O    1 
HETATM 12011 O O    . HOH E 3 .   ? 11.070  9.460   15.995 1.00 18.46 ?  632  HOH A O    1 
HETATM 12012 O O    . HOH E 3 .   ? -16.895 8.511   29.746 1.00 12.30 ?  633  HOH A O    1 
HETATM 12013 O O    . HOH E 3 .   ? -22.776 33.578  16.398 1.00 23.23 ?  634  HOH A O    1 
HETATM 12014 O O    . HOH E 3 .   ? 7.668   21.043  49.467 1.00 24.96 ?  635  HOH A O    1 
HETATM 12015 O O    . HOH E 3 .   ? 0.987   3.410   10.683 1.00 36.45 ?  636  HOH A O    1 
HETATM 12016 O O    . HOH E 3 .   ? -30.093 29.857  16.726 1.00 32.47 ?  637  HOH A O    1 
HETATM 12017 O O    . HOH E 3 .   ? -0.861  -1.669  14.388 1.00 22.25 ?  638  HOH A O    1 
HETATM 12018 O O    . HOH E 3 .   ? 2.024   15.164  44.325 1.00 36.90 ?  639  HOH A O    1 
HETATM 12019 O O    . HOH E 3 .   ? -11.169 8.652   37.867 1.00 16.88 ?  640  HOH A O    1 
HETATM 12020 O O    . HOH E 3 .   ? 6.209   21.813  51.734 1.00 20.79 ?  641  HOH A O    1 
HETATM 12021 O O    . HOH E 3 .   ? -29.909 -0.618  30.926 1.00 43.46 ?  642  HOH A O    1 
HETATM 12022 O O    . HOH E 3 .   ? -16.791 3.512   10.970 1.00 23.58 ?  643  HOH A O    1 
HETATM 12023 O O    . HOH E 3 .   ? -18.595 13.375  26.065 1.00 11.60 ?  644  HOH A O    1 
HETATM 12024 O O    . HOH E 3 .   ? -26.006 20.280  6.907  1.00 20.17 ?  645  HOH A O    1 
HETATM 12025 O O    . HOH E 3 .   ? -30.682 20.376  13.561 1.00 15.98 ?  646  HOH A O    1 
HETATM 12026 O O    . HOH E 3 .   ? -0.714  -11.902 22.555 1.00 37.75 ?  647  HOH A O    1 
HETATM 12027 O O    . HOH E 3 .   ? 5.966   15.427  34.649 1.00 23.32 ?  648  HOH A O    1 
HETATM 12028 O O    . HOH E 3 .   ? -19.268 10.604  4.932  1.00 19.73 ?  649  HOH A O    1 
HETATM 12029 O O    . HOH E 3 .   ? -19.462 35.230  17.445 1.00 18.80 ?  650  HOH A O    1 
HETATM 12030 O O    . HOH E 3 .   ? -15.724 -15.878 43.514 1.00 36.31 ?  651  HOH A O    1 
HETATM 12031 O O    . HOH E 3 .   ? -24.463 1.134   48.304 1.00 34.95 ?  652  HOH A O    1 
HETATM 12032 O O    . HOH E 3 .   ? 6.083   24.060  42.590 1.00 23.60 ?  653  HOH A O    1 
HETATM 12033 O O    . HOH E 3 .   ? -16.851 -16.836 35.445 1.00 29.69 ?  654  HOH A O    1 
HETATM 12034 O O    . HOH E 3 .   ? -21.984 -8.156  32.449 1.00 26.70 ?  655  HOH A O    1 
HETATM 12035 O O    . HOH E 3 .   ? -4.017  29.072  17.730 1.00 26.54 ?  656  HOH A O    1 
HETATM 12036 O O    . HOH E 3 .   ? -10.960 31.017  26.633 1.00 31.74 ?  657  HOH A O    1 
HETATM 12037 O O    . HOH E 3 .   ? -33.871 9.953   28.882 1.00 42.52 ?  658  HOH A O    1 
HETATM 12038 O O    . HOH E 3 .   ? -29.083 31.499  14.135 1.00 25.94 ?  659  HOH A O    1 
HETATM 12039 O O    . HOH E 3 .   ? -25.147 0.037   33.102 1.00 18.53 ?  660  HOH A O    1 
HETATM 12040 O O    . HOH E 3 .   ? 11.572  6.439   27.087 1.00 25.11 ?  661  HOH A O    1 
HETATM 12041 O O    . HOH E 3 .   ? 5.235   26.099  26.983 1.00 20.19 ?  662  HOH A O    1 
HETATM 12042 O O    . HOH E 3 .   ? -11.934 -10.914 24.754 1.00 20.46 ?  663  HOH A O    1 
HETATM 12043 O O    . HOH E 3 .   ? 8.848   11.968  34.685 1.00 33.65 ?  664  HOH A O    1 
HETATM 12044 O O    . HOH E 3 .   ? 3.993   1.378   27.602 1.00 23.68 ?  665  HOH A O    1 
HETATM 12045 O O    . HOH E 3 .   ? -32.175 30.401  25.325 1.00 20.63 ?  666  HOH A O    1 
HETATM 12046 O O    . HOH E 3 .   ? 2.607   -5.479  41.793 1.00 23.39 ?  667  HOH A O    1 
HETATM 12047 O O    . HOH E 3 .   ? -17.903 25.367  5.591  1.00 15.31 ?  668  HOH A O    1 
HETATM 12048 O O    . HOH E 3 .   ? 12.410  2.002   15.962 1.00 38.00 ?  669  HOH A O    1 
HETATM 12049 O O    . HOH E 3 .   ? -16.256 19.691  31.061 1.00 12.82 ?  670  HOH A O    1 
HETATM 12050 O O    . HOH E 3 .   ? -24.510 26.428  3.583  1.00 20.22 ?  671  HOH A O    1 
HETATM 12051 O O    . HOH E 3 .   ? -29.309 14.037  36.131 1.00 29.30 ?  672  HOH A O    1 
HETATM 12052 O O    . HOH E 3 .   ? -9.089  33.379  5.302  1.00 42.54 ?  673  HOH A O    1 
HETATM 12053 O O    . HOH E 3 .   ? -14.517 34.865  24.525 1.00 28.54 ?  674  HOH A O    1 
HETATM 12054 O O    . HOH E 3 .   ? -4.263  16.880  18.732 1.00 12.32 ?  675  HOH A O    1 
HETATM 12055 O O    . HOH E 3 .   ? -25.800 25.874  31.811 1.00 24.43 ?  676  HOH A O    1 
HETATM 12056 O O    . HOH E 3 .   ? -8.652  27.119  18.502 1.00 12.05 ?  677  HOH A O    1 
HETATM 12057 O O    . HOH E 3 .   ? -17.597 6.419   32.422 1.00 14.24 ?  678  HOH A O    1 
HETATM 12058 O O    . HOH E 3 .   ? 6.702   -2.426  16.096 1.00 38.43 ?  679  HOH A O    1 
HETATM 12059 O O    . HOH E 3 .   ? -26.967 -2.262  16.966 1.00 42.82 ?  680  HOH A O    1 
HETATM 12060 O O    . HOH E 3 .   ? -29.770 13.535  12.263 1.00 21.30 ?  681  HOH A O    1 
HETATM 12061 O O    . HOH E 3 .   ? -26.049 -0.165  41.049 1.00 25.80 ?  682  HOH A O    1 
HETATM 12062 O O    . HOH E 3 .   ? 6.834   12.532  35.585 1.00 34.10 ?  683  HOH A O    1 
HETATM 12063 O O    . HOH E 3 .   ? 9.752   0.963   36.706 1.00 45.31 ?  684  HOH A O    1 
HETATM 12064 O O    . HOH E 3 .   ? -9.646  27.907  8.740  1.00 15.87 ?  685  HOH A O    1 
HETATM 12065 O O    . HOH E 3 .   ? -29.209 2.913   33.192 1.00 22.60 ?  686  HOH A O    1 
HETATM 12066 O O    . HOH E 3 .   ? -23.991 -1.041  22.054 1.00 29.09 ?  687  HOH A O    1 
HETATM 12067 O O    . HOH E 3 .   ? 2.309   26.436  41.637 1.00 19.10 ?  688  HOH A O    1 
HETATM 12068 O O    . HOH E 3 .   ? -1.225  17.242  43.067 1.00 44.17 ?  689  HOH A O    1 
HETATM 12069 O O    . HOH E 3 .   ? 12.156  4.346   11.366 1.00 43.01 ?  690  HOH A O    1 
HETATM 12070 O O    . HOH E 3 .   ? 8.708   3.827   32.206 1.00 36.41 ?  691  HOH A O    1 
HETATM 12071 O O    . HOH E 3 .   ? -2.120  -7.619  18.133 1.00 21.34 ?  692  HOH A O    1 
HETATM 12072 O O    . HOH E 3 .   ? 6.111   -10.507 32.337 1.00 37.97 ?  693  HOH A O    1 
HETATM 12073 O O    . HOH E 3 .   ? -1.198  16.843  38.457 1.00 20.29 ?  694  HOH A O    1 
HETATM 12074 O O    . HOH E 3 .   ? -17.394 -5.108  52.587 1.00 46.39 ?  695  HOH A O    1 
HETATM 12075 O O    . HOH E 3 .   ? -2.650  -6.983  45.796 1.00 26.24 ?  696  HOH A O    1 
HETATM 12076 O O    . HOH E 3 .   ? 7.900   4.018   10.459 1.00 38.33 ?  697  HOH A O    1 
HETATM 12077 O O    . HOH E 3 .   ? -0.085  -19.843 35.364 1.00 44.70 ?  698  HOH A O    1 
HETATM 12078 O O    . HOH E 3 .   ? 6.340   29.805  21.785 1.00 27.96 ?  699  HOH A O    1 
HETATM 12079 O O    . HOH E 3 .   ? -19.870 30.870  32.100 1.00 20.39 ?  700  HOH A O    1 
HETATM 12080 O O    . HOH E 3 .   ? -12.414 11.067  35.490 1.00 15.16 ?  701  HOH A O    1 
HETATM 12081 O O    . HOH E 3 .   ? -4.606  -2.236  12.273 1.00 21.16 ?  702  HOH A O    1 
HETATM 12082 O O    . HOH E 3 .   ? -13.436 -15.726 39.688 1.00 27.87 ?  703  HOH A O    1 
HETATM 12083 O O    . HOH E 3 .   ? -6.529  3.014   9.845  1.00 18.61 ?  704  HOH A O    1 
HETATM 12084 O O    . HOH E 3 .   ? -2.163  21.363  38.675 1.00 27.19 ?  705  HOH A O    1 
HETATM 12085 O O    . HOH E 3 .   ? -9.865  -15.810 27.251 1.00 27.22 ?  706  HOH A O    1 
HETATM 12086 O O    . HOH E 3 .   ? -24.804 12.528  44.436 1.00 31.08 ?  707  HOH A O    1 
HETATM 12087 O O    . HOH E 3 .   ? -9.971  -14.252 42.621 1.00 32.15 ?  708  HOH A O    1 
HETATM 12088 O O    . HOH E 3 .   ? -6.462  29.936  20.260 1.00 16.41 ?  709  HOH A O    1 
HETATM 12089 O O    . HOH E 3 .   ? -25.077 6.290   9.722  1.00 35.23 ?  710  HOH A O    1 
HETATM 12090 O O    . HOH E 3 .   ? 9.862   26.487  18.140 1.00 24.48 ?  711  HOH A O    1 
HETATM 12091 O O    . HOH E 3 .   ? -31.046 5.618   33.506 1.00 20.08 ?  712  HOH A O    1 
HETATM 12092 O O    . HOH E 3 .   ? -23.620 -0.055  10.634 1.00 31.85 ?  713  HOH A O    1 
HETATM 12093 O O    . HOH E 3 .   ? 1.420   28.934  20.113 1.00 33.36 ?  714  HOH A O    1 
HETATM 12094 O O    . HOH E 3 .   ? -22.640 36.739  26.044 1.00 27.24 ?  715  HOH A O    1 
HETATM 12095 O O    . HOH E 3 .   ? -29.131 2.020   20.212 1.00 28.83 ?  716  HOH A O    1 
HETATM 12096 O O    . HOH E 3 .   ? -21.392 12.426  33.797 1.00 16.50 ?  717  HOH A O    1 
HETATM 12097 O O    . HOH E 3 .   ? -28.154 17.185  8.933  1.00 29.42 ?  718  HOH A O    1 
HETATM 12098 O O    . HOH E 3 .   ? 5.028   9.692   47.807 1.00 43.65 ?  719  HOH A O    1 
HETATM 12099 O O    . HOH E 3 .   ? -15.819 -9.886  33.047 1.00 18.16 ?  720  HOH A O    1 
HETATM 12100 O O    . HOH E 3 .   ? -11.202 19.984  19.009 1.00 10.33 ?  721  HOH A O    1 
HETATM 12101 O O    . HOH E 3 .   ? 7.005   21.632  41.847 1.00 26.50 ?  722  HOH A O    1 
HETATM 12102 O O    . HOH E 3 .   ? -22.170 17.990  2.266  1.00 28.12 ?  723  HOH A O    1 
HETATM 12103 O O    . HOH E 3 .   ? -21.668 -13.037 38.319 1.00 29.66 ?  724  HOH A O    1 
HETATM 12104 O O    . HOH E 3 .   ? -32.226 28.210  28.918 1.00 28.18 ?  725  HOH A O    1 
HETATM 12105 O O    . HOH E 3 .   ? -15.107 -13.034 26.115 1.00 26.97 ?  726  HOH A O    1 
HETATM 12106 O O    . HOH E 3 .   ? -20.463 6.379   48.468 1.00 30.28 ?  727  HOH A O    1 
HETATM 12107 O O    . HOH E 3 .   ? -3.870  -4.195  47.241 1.00 26.16 ?  728  HOH A O    1 
HETATM 12108 O O    . HOH E 3 .   ? -24.414 15.486  6.479  1.00 22.20 ?  729  HOH A O    1 
HETATM 12109 O O    . HOH E 3 .   ? -5.046  0.179   9.693  1.00 25.13 ?  730  HOH A O    1 
HETATM 12110 O O    . HOH E 3 .   ? -1.850  14.859  41.981 1.00 33.00 ?  731  HOH A O    1 
HETATM 12111 O O    . HOH E 3 .   ? -20.049 -8.504  14.257 1.00 22.71 ?  732  HOH A O    1 
HETATM 12112 O O    . HOH E 3 .   ? -3.620  22.698  32.460 1.00 27.30 ?  733  HOH A O    1 
HETATM 12113 O O    . HOH E 3 .   ? -27.599 19.145  22.195 1.00 22.84 ?  734  HOH A O    1 
HETATM 12114 O O    . HOH E 3 .   ? -33.743 12.544  22.218 1.00 31.18 ?  735  HOH A O    1 
HETATM 12115 O O    . HOH E 3 .   ? -23.055 37.879  22.802 1.00 29.30 ?  736  HOH A O    1 
HETATM 12116 O O    . HOH E 3 .   ? 9.797   0.345   18.570 1.00 33.43 ?  737  HOH A O    1 
HETATM 12117 O O    . HOH E 3 .   ? -12.095 -8.696  11.406 1.00 26.83 ?  738  HOH A O    1 
HETATM 12118 O O    . HOH E 3 .   ? 9.391   6.773   42.624 1.00 39.84 ?  739  HOH A O    1 
HETATM 12119 O O    . HOH E 3 .   ? 6.373   22.711  27.912 1.00 30.65 ?  740  HOH A O    1 
HETATM 12120 O O    . HOH E 3 .   ? -3.775  25.431  26.425 1.00 19.68 ?  741  HOH A O    1 
HETATM 12121 O O    . HOH E 3 .   ? 5.625   -1.322  46.024 1.00 38.38 ?  742  HOH A O    1 
HETATM 12122 O O    . HOH E 3 .   ? -4.075  -5.045  10.456 1.00 38.90 ?  743  HOH A O    1 
HETATM 12123 O O    . HOH E 3 .   ? -12.309 22.487  7.409  1.00 14.24 ?  744  HOH A O    1 
HETATM 12124 O O    . HOH E 3 .   ? -16.102 35.043  22.547 1.00 26.86 ?  745  HOH A O    1 
HETATM 12125 O O    . HOH E 3 .   ? -33.781 14.114  11.329 1.00 44.57 ?  746  HOH A O    1 
HETATM 12126 O O    . HOH E 3 .   ? 9.013   3.591   35.945 1.00 35.07 ?  747  HOH A O    1 
HETATM 12127 O O    . HOH E 3 .   ? -19.606 6.114   34.442 1.00 16.04 ?  748  HOH A O    1 
HETATM 12128 O O    . HOH E 3 .   ? -15.669 -2.741  13.158 1.00 26.47 ?  749  HOH A O    1 
HETATM 12129 O O    . HOH E 3 .   ? -17.568 -12.407 43.649 1.00 29.64 ?  750  HOH A O    1 
HETATM 12130 O O    . HOH E 3 .   ? -28.046 1.583   40.773 1.00 34.73 ?  751  HOH A O    1 
HETATM 12131 O O    . HOH E 3 .   ? -1.368  20.477  46.006 1.00 43.49 ?  752  HOH A O    1 
HETATM 12132 O O    . HOH E 3 .   ? -7.290  0.138   48.415 1.00 39.30 ?  753  HOH A O    1 
HETATM 12133 O O    . HOH E 3 .   ? -36.409 21.816  17.457 1.00 24.98 ?  754  HOH A O    1 
HETATM 12134 O O    . HOH E 3 .   ? -10.322 28.065  25.114 1.00 26.56 ?  755  HOH A O    1 
HETATM 12135 O O    . HOH E 3 .   ? 5.941   2.154   51.339 1.00 34.98 ?  756  HOH A O    1 
HETATM 12136 O O    . HOH E 3 .   ? 7.141   -5.911  37.822 1.00 41.20 ?  757  HOH A O    1 
HETATM 12137 O O    . HOH E 3 .   ? 5.671   -12.010 35.724 1.00 29.15 ?  758  HOH A O    1 
HETATM 12138 O O    . HOH E 3 .   ? -5.721  12.152  38.366 1.00 20.48 ?  759  HOH A O    1 
HETATM 12139 O O    . HOH E 3 .   ? -30.132 11.200  26.670 1.00 33.90 ?  760  HOH A O    1 
HETATM 12140 O O    . HOH E 3 .   ? -26.097 35.424  28.871 1.00 37.55 ?  761  HOH A O    1 
HETATM 12141 O O    . HOH E 3 .   ? -21.092 -7.101  48.936 1.00 31.16 ?  762  HOH A O    1 
HETATM 12142 O O    . HOH E 3 .   ? 6.443   16.704  19.696 1.00 14.77 ?  763  HOH A O    1 
HETATM 12143 O O    . HOH E 3 .   ? 8.356   0.637   13.418 1.00 30.99 ?  764  HOH A O    1 
HETATM 12144 O O    . HOH E 3 .   ? 12.009  6.398   29.542 1.00 38.27 ?  765  HOH A O    1 
HETATM 12145 O O    . HOH E 3 .   ? 15.251  15.189  22.621 1.00 20.32 ?  766  HOH A O    1 
HETATM 12146 O O    . HOH E 3 .   ? -10.501 5.505   3.615  1.00 31.55 ?  767  HOH A O    1 
HETATM 12147 O O    . HOH E 3 .   ? -2.369  18.819  34.986 1.00 21.25 ?  768  HOH A O    1 
HETATM 12148 O O    . HOH E 3 .   ? -8.403  22.236  10.445 1.00 14.24 ?  769  HOH A O    1 
HETATM 12149 O O    . HOH E 3 .   ? -13.105 -15.669 36.531 1.00 26.91 ?  770  HOH A O    1 
HETATM 12150 O O    . HOH E 3 .   ? -4.425  32.107  15.803 1.00 27.48 ?  771  HOH A O    1 
HETATM 12151 O O    . HOH E 3 .   ? -11.463 0.242   53.460 1.00 46.06 ?  772  HOH A O    1 
HETATM 12152 O O    . HOH E 3 .   ? -10.738 29.068  20.635 1.00 20.54 ?  773  HOH A O    1 
HETATM 12153 O O    . HOH E 3 .   ? -23.920 8.636   19.533 1.00 19.91 ?  774  HOH A O    1 
HETATM 12154 O O    . HOH E 3 .   ? -20.100 37.662  24.857 1.00 42.65 ?  775  HOH A O    1 
HETATM 12155 O O    . HOH E 3 .   ? 2.710   4.718   35.432 1.00 36.90 ?  776  HOH A O    1 
HETATM 12156 O O    . HOH E 3 .   ? 7.332   10.351  8.898  1.00 33.39 ?  777  HOH A O    1 
HETATM 12157 O O    . HOH E 3 .   ? 4.251   18.485  38.621 1.00 35.42 ?  778  HOH A O    1 
HETATM 12158 O O    . HOH E 3 .   ? 7.274   12.929  41.546 1.00 35.87 ?  779  HOH A O    1 
HETATM 12159 O O    . HOH E 3 .   ? -15.055 -12.407 49.244 1.00 40.94 ?  780  HOH A O    1 
HETATM 12160 O O    . HOH E 3 .   ? -25.368 -0.458  30.301 1.00 22.49 ?  781  HOH A O    1 
HETATM 12161 O O    . HOH E 3 .   ? -2.859  -12.342 23.919 1.00 18.85 ?  782  HOH A O    1 
HETATM 12162 O O    . HOH E 3 .   ? 1.406   29.203  14.244 1.00 29.14 ?  783  HOH A O    1 
HETATM 12163 O O    . HOH E 3 .   ? -6.145  16.505  32.346 1.00 18.10 ?  784  HOH A O    1 
HETATM 12164 O O    . HOH E 3 .   ? -3.769  18.100  32.377 1.00 30.35 ?  785  HOH A O    1 
HETATM 12165 O O    . HOH E 3 .   ? -30.004 17.772  34.807 1.00 38.06 ?  786  HOH A O    1 
HETATM 12166 O O    . HOH E 3 .   ? -25.285 12.636  7.620  1.00 29.67 ?  787  HOH A O    1 
HETATM 12167 O O    . HOH E 3 .   ? 2.999   5.801   9.457  1.00 36.42 ?  788  HOH A O    1 
HETATM 12168 O O    . HOH E 3 .   ? 2.609   -0.805  26.648 1.00 26.89 ?  789  HOH A O    1 
HETATM 12169 O O    . HOH E 3 .   ? 2.021   25.222  48.917 1.00 26.17 ?  790  HOH A O    1 
HETATM 12170 O O    . HOH E 3 .   ? -19.234 -9.135  36.844 1.00 25.52 ?  791  HOH A O    1 
HETATM 12171 O O    . HOH E 3 .   ? 0.309   -2.351  26.867 1.00 16.90 ?  792  HOH A O    1 
HETATM 12172 O O    . HOH E 3 .   ? 5.360   11.095  7.423  1.00 27.86 ?  793  HOH A O    1 
HETATM 12173 O O    . HOH E 3 .   ? -6.547  37.300  6.838  1.00 37.59 ?  794  HOH A O    1 
HETATM 12174 O O    . HOH E 3 .   ? -18.801 8.333   14.255 1.00 34.22 ?  795  HOH A O    1 
HETATM 12175 O O    . HOH E 3 .   ? -13.585 -13.928 29.829 1.00 21.77 ?  796  HOH A O    1 
HETATM 12176 O O    . HOH E 3 .   ? -18.758 -10.038 32.687 1.00 29.02 ?  797  HOH A O    1 
HETATM 12177 O O    . HOH E 3 .   ? -8.223  37.606  13.856 1.00 47.31 ?  798  HOH A O    1 
HETATM 12178 O O    . HOH E 3 .   ? -16.904 8.185   47.758 1.00 42.87 ?  799  HOH A O    1 
HETATM 12179 O O    . HOH E 3 .   ? -20.233 3.046   48.248 1.00 27.61 ?  800  HOH A O    1 
HETATM 12180 O O    . HOH E 3 .   ? 2.567   3.554   52.357 1.00 34.87 ?  801  HOH A O    1 
HETATM 12181 O O    . HOH E 3 .   ? 4.185   -11.764 30.296 1.00 35.46 ?  802  HOH A O    1 
HETATM 12182 O O    . HOH E 3 .   ? -27.309 12.960  7.669  1.00 42.61 ?  803  HOH A O    1 
HETATM 12183 O O    . HOH E 3 .   ? -36.596 26.425  23.195 1.00 17.20 ?  804  HOH A O    1 
HETATM 12184 O O    . HOH E 3 .   ? 15.628  12.488  25.178 1.00 19.67 ?  805  HOH A O    1 
HETATM 12185 O O    . HOH E 3 .   ? 14.078  6.036   25.634 1.00 28.19 ?  806  HOH A O    1 
HETATM 12186 O O    . HOH E 3 .   ? -8.517  27.489  25.385 1.00 24.93 ?  807  HOH A O    1 
HETATM 12187 O O    . HOH E 3 .   ? -33.735 8.005   35.135 1.00 42.13 ?  808  HOH A O    1 
HETATM 12188 O O    . HOH E 3 .   ? 1.275   -13.756 30.547 1.00 30.49 ?  809  HOH A O    1 
HETATM 12189 O O    . HOH E 3 .   ? -31.388 16.362  31.036 1.00 21.47 ?  810  HOH A O    1 
HETATM 12190 O O    . HOH E 3 .   ? 8.188   2.647   27.737 1.00 34.55 ?  811  HOH A O    1 
HETATM 12191 O O    . HOH E 3 .   ? -14.393 26.278  31.282 1.00 15.12 ?  812  HOH A O    1 
HETATM 12192 O O    . HOH E 3 .   ? -30.866 29.464  21.120 1.00 22.13 ?  813  HOH A O    1 
HETATM 12193 O O    . HOH E 3 .   ? -23.000 31.522  29.043 1.00 22.54 ?  814  HOH A O    1 
HETATM 12194 O O    . HOH E 3 .   ? -5.917  7.406   7.077  1.00 15.04 ?  815  HOH A O    1 
HETATM 12195 O O    . HOH E 3 .   ? -11.097 37.999  15.350 1.00 37.91 ?  816  HOH A O    1 
HETATM 12196 O O    . HOH E 3 .   ? 5.948   -1.374  21.577 1.00 46.93 ?  817  HOH A O    1 
HETATM 12197 O O    . HOH E 3 .   ? -6.541  33.615  12.828 1.00 30.79 ?  818  HOH A O    1 
HETATM 12198 O O    . HOH E 3 .   ? 1.125   -11.440 44.045 1.00 29.13 ?  819  HOH A O    1 
HETATM 12199 O O    . HOH E 3 .   ? -1.910  28.153  25.259 1.00 28.30 ?  820  HOH A O    1 
HETATM 12200 O O    . HOH E 3 .   ? 0.248   -14.914 28.223 1.00 33.44 ?  821  HOH A O    1 
HETATM 12201 O O    . HOH E 3 .   ? -35.784 22.670  14.188 1.00 38.82 ?  822  HOH A O    1 
HETATM 12202 O O    . HOH E 3 .   ? -15.855 -10.735 23.420 1.00 36.27 ?  823  HOH A O    1 
HETATM 12203 O O    . HOH E 3 .   ? 0.606   22.321  41.857 1.00 43.95 ?  824  HOH A O    1 
HETATM 12204 O O    . HOH E 3 .   ? -6.451  -2.246  47.640 1.00 29.80 ?  825  HOH A O    1 
HETATM 12205 O O    . HOH E 3 .   ? -6.622  33.401  18.699 1.00 35.72 ?  826  HOH A O    1 
HETATM 12206 O O    . HOH E 3 .   ? -9.885  2.053   50.753 1.00 44.60 ?  827  HOH A O    1 
HETATM 12207 O O    . HOH E 3 .   ? -19.253 -12.578 25.856 1.00 32.14 ?  828  HOH A O    1 
HETATM 12208 O O    . HOH E 3 .   ? -19.018 -5.512  50.111 1.00 39.13 ?  829  HOH A O    1 
HETATM 12209 O O    . HOH E 3 .   ? -13.642 31.182  6.063  1.00 33.83 ?  830  HOH A O    1 
HETATM 12210 O O    . HOH E 3 .   ? -17.014 -17.431 32.892 1.00 35.00 ?  831  HOH A O    1 
HETATM 12211 O O    . HOH E 3 .   ? 1.017   17.230  45.686 1.00 35.28 ?  832  HOH A O    1 
HETATM 12212 O O    . HOH E 3 .   ? 0.757   -19.038 31.771 1.00 44.29 ?  833  HOH A O    1 
HETATM 12213 O O    . HOH E 3 .   ? -21.394 24.312  31.413 1.00 19.33 ?  834  HOH A O    1 
HETATM 12214 O O    . HOH E 3 .   ? -11.399 29.694  23.213 1.00 34.13 ?  835  HOH A O    1 
HETATM 12215 O O    . HOH E 3 .   ? -14.577 5.378   3.495  1.00 45.61 ?  836  HOH A O    1 
HETATM 12216 O O    . HOH E 3 .   ? -15.061 0.708   11.369 1.00 30.14 ?  837  HOH A O    1 
HETATM 12217 O O    . HOH E 3 .   ? -1.274  28.168  19.274 1.00 32.42 ?  838  HOH A O    1 
HETATM 12218 O O    . HOH E 3 .   ? -1.921  -4.667  24.353 1.00 17.05 ?  839  HOH A O    1 
HETATM 12219 O O    . HOH E 3 .   ? 6.497   8.840   10.293 1.00 28.77 ?  840  HOH A O    1 
HETATM 12220 O O    . HOH E 3 .   ? 2.085   8.795   32.184 1.00 31.86 ?  841  HOH A O    1 
HETATM 12221 O O    . HOH E 3 .   ? 4.510   21.103  36.706 1.00 32.53 ?  842  HOH A O    1 
HETATM 12222 O O    . HOH E 3 .   ? -2.175  28.440  8.320  1.00 33.17 ?  843  HOH A O    1 
HETATM 12223 O O    . HOH E 3 .   ? 3.578   21.946  41.071 1.00 30.18 ?  844  HOH A O    1 
HETATM 12224 O O    . HOH E 3 .   ? 8.168   0.762   20.746 1.00 25.07 ?  845  HOH A O    1 
HETATM 12225 O O    . HOH E 3 .   ? 2.361   16.855  53.664 1.00 38.26 ?  846  HOH A O    1 
HETATM 12226 O O    . HOH E 3 .   ? 18.099  10.801  22.198 1.00 45.15 ?  847  HOH A O    1 
HETATM 12227 O O    . HOH E 3 .   ? -26.564 28.547  31.595 1.00 29.79 ?  848  HOH A O    1 
HETATM 12228 O O    . HOH E 3 .   ? -32.102 33.400  25.988 1.00 31.55 ?  849  HOH A O    1 
HETATM 12229 O O    . HOH E 3 .   ? 1.052   11.111  48.714 1.00 44.21 ?  850  HOH A O    1 
HETATM 12230 O O    . HOH E 3 .   ? 8.508   22.986  28.354 1.00 48.68 ?  851  HOH A O    1 
HETATM 12231 O O    . HOH E 3 .   ? -2.900  6.599   7.919  1.00 18.03 ?  852  HOH A O    1 
HETATM 12232 O O    . HOH E 3 .   ? 3.884   -3.273  42.980 1.00 27.98 ?  853  HOH A O    1 
HETATM 12233 O O    . HOH E 3 .   ? 8.365   12.413  37.556 1.00 41.29 ?  854  HOH A O    1 
HETATM 12234 O O    . HOH E 3 .   ? -7.171  -20.514 37.531 1.00 35.48 ?  855  HOH A O    1 
HETATM 12235 O O    . HOH E 3 .   ? 6.085   -1.880  24.050 1.00 36.62 ?  856  HOH A O    1 
HETATM 12236 O O    . HOH E 3 .   ? -5.229  29.588  23.554 1.00 37.49 ?  857  HOH A O    1 
HETATM 12237 O O    . HOH E 3 .   ? -12.438 -16.370 29.253 1.00 28.78 ?  858  HOH A O    1 
HETATM 12238 O O    . HOH E 3 .   ? 2.273   -6.595  18.524 1.00 40.23 ?  859  HOH A O    1 
HETATM 12239 O O    . HOH E 3 .   ? 7.509   14.479  8.943  1.00 42.70 ?  860  HOH A O    1 
HETATM 12240 O O    . HOH E 3 .   ? 16.031  7.989   20.863 1.00 42.28 ?  861  HOH A O    1 
HETATM 12241 O O    . HOH E 3 .   ? 2.352   30.687  24.978 1.00 30.33 ?  862  HOH A O    1 
HETATM 12242 O O    . HOH E 3 .   ? -2.505  -15.846 26.548 1.00 34.73 ?  863  HOH A O    1 
HETATM 12243 O O    . HOH E 3 .   ? 5.591   16.910  37.207 1.00 37.88 ?  864  HOH A O    1 
HETATM 12244 O O    . HOH E 3 .   ? 13.732  5.064   14.683 1.00 45.91 ?  865  HOH A O    1 
HETATM 12245 O O    . HOH E 3 .   ? 16.579  6.034   21.059 1.00 48.90 ?  866  HOH A O    1 
HETATM 12246 O O    . HOH E 3 .   ? 11.498  14.809  30.133 1.00 29.43 ?  867  HOH A O    1 
HETATM 12247 O O    . HOH E 3 .   ? -11.565 25.609  31.258 1.00 27.84 ?  868  HOH A O    1 
HETATM 12248 O O    . HOH E 3 .   ? 5.246   17.474  10.954 1.00 23.40 ?  869  HOH A O    1 
HETATM 12249 O O    . HOH E 3 .   ? 0.310   22.772  48.047 1.00 29.87 ?  870  HOH A O    1 
HETATM 12250 O O    . HOH E 3 .   ? -7.593  -6.076  5.918  1.00 51.70 ?  871  HOH A O    1 
HETATM 12251 O O    . HOH E 3 .   ? -40.126 21.491  22.571 1.00 33.72 ?  872  HOH A O    1 
HETATM 12252 O O    . HOH E 3 .   ? -19.409 2.369   7.987  1.00 33.39 ?  873  HOH A O    1 
HETATM 12253 O O    . HOH E 3 .   ? -32.106 10.017  20.599 1.00 41.64 ?  874  HOH A O    1 
HETATM 12254 O O    . HOH E 3 .   ? -21.051 37.522  17.571 1.00 31.55 ?  875  HOH A O    1 
HETATM 12255 O O    . HOH E 3 .   ? -42.091 24.207  20.674 1.00 35.77 ?  876  HOH A O    1 
HETATM 12256 O O    . HOH E 3 .   ? -5.504  27.698  25.626 1.00 30.06 ?  877  HOH A O    1 
HETATM 12257 O O    . HOH E 3 .   ? -29.293 13.615  43.130 1.00 43.01 ?  878  HOH A O    1 
HETATM 12258 O O    . HOH E 3 .   ? -32.014 14.293  35.098 1.00 48.93 ?  879  HOH A O    1 
HETATM 12259 O O    . HOH E 3 .   ? -28.027 7.227   37.300 1.00 24.71 ?  880  HOH A O    1 
HETATM 12260 O O    . HOH E 3 .   ? 11.627  20.935  49.443 1.00 46.78 ?  881  HOH A O    1 
HETATM 12261 O O    . HOH E 3 .   ? -1.124  -1.483  11.767 1.00 31.33 ?  882  HOH A O    1 
HETATM 12262 O O    . HOH E 3 .   ? -22.298 24.523  4.090  1.00 16.02 ?  883  HOH A O    1 
HETATM 12263 O O    . HOH E 3 .   ? -6.411  25.525  6.351  1.00 36.64 ?  884  HOH A O    1 
HETATM 12264 O O    . HOH E 3 .   ? -0.669  18.441  40.751 1.00 33.34 ?  885  HOH A O    1 
HETATM 12265 O O    . HOH E 3 .   ? -28.590 11.385  11.259 1.00 23.63 ?  886  HOH A O    1 
HETATM 12266 O O    . HOH E 3 .   ? -2.583  -7.356  14.220 1.00 41.55 ?  887  HOH A O    1 
HETATM 12267 O O    . HOH E 3 .   ? -23.990 10.319  6.465  1.00 31.04 ?  888  HOH A O    1 
HETATM 12268 O O    . HOH E 3 .   ? 8.428   27.508  24.030 1.00 43.68 ?  889  HOH A O    1 
HETATM 12269 O O    . HOH E 3 .   ? -9.694  13.053  33.623 1.00 17.59 ?  890  HOH A O    1 
HETATM 12270 O O    . HOH E 3 .   ? -6.650  2.470   47.635 1.00 41.97 ?  891  HOH A O    1 
HETATM 12271 O O    . HOH E 3 .   ? -32.830 12.258  28.300 1.00 31.29 ?  892  HOH A O    1 
HETATM 12272 O O    . HOH E 3 .   ? -16.079 13.138  34.086 1.00 19.72 ?  893  HOH A O    1 
HETATM 12273 O O    . HOH E 3 .   ? -6.901  15.426  2.646  1.00 34.38 ?  894  HOH A O    1 
HETATM 12274 O O    . HOH E 3 .   ? -34.763 40.974  26.103 1.00 47.95 ?  895  HOH A O    1 
HETATM 12275 O O    . HOH E 3 .   ? -34.817 19.463  16.081 1.00 29.16 ?  896  HOH A O    1 
HETATM 12276 O O    . HOH E 3 .   ? -18.181 0.935   13.915 1.00 26.01 ?  897  HOH A O    1 
HETATM 12277 O O    . HOH E 3 .   ? -31.845 30.684  27.989 1.00 33.49 ?  898  HOH A O    1 
HETATM 12278 O O    . HOH E 3 .   ? -6.589  15.070  36.608 1.00 40.32 ?  899  HOH A O    1 
HETATM 12279 O O    . HOH E 3 .   ? -8.009  24.644  25.497 1.00 23.59 ?  900  HOH A O    1 
HETATM 12280 O O    . HOH E 3 .   ? 10.180  3.862   26.664 1.00 32.00 ?  901  HOH A O    1 
HETATM 12281 O O    . HOH E 3 .   ? 17.192  11.046  30.405 1.00 42.86 ?  902  HOH A O    1 
HETATM 12282 O O    . HOH E 3 .   ? -21.913 13.098  36.873 1.00 23.78 ?  903  HOH A O    1 
HETATM 12283 O O    . HOH E 3 .   ? -4.276  31.391  21.077 1.00 37.39 ?  904  HOH A O    1 
HETATM 12284 O O    . HOH E 3 .   ? 17.578  13.796  23.539 1.00 25.24 ?  905  HOH A O    1 
HETATM 12285 O O    . HOH E 3 .   ? -35.051 17.538  12.883 1.00 33.58 ?  906  HOH A O    1 
HETATM 12286 O O    . HOH E 3 .   ? -33.028 11.711  34.026 1.00 40.97 ?  907  HOH A O    1 
HETATM 12287 O O    . HOH E 3 .   ? 16.880  10.218  24.862 1.00 29.27 ?  908  HOH A O    1 
HETATM 12288 O O    . HOH E 3 .   ? 6.881   6.033   9.587  1.00 38.14 ?  909  HOH A O    1 
HETATM 12289 O O    . HOH E 3 .   ? -6.544  21.514  32.430 1.00 25.74 ?  910  HOH A O    1 
HETATM 12290 O O    . HOH E 3 .   ? -27.720 0.454   19.449 1.00 37.10 ?  911  HOH A O    1 
HETATM 12291 O O    . HOH E 3 .   ? -17.797 9.163   2.996  1.00 29.37 ?  912  HOH A O    1 
HETATM 12292 O O    . HOH E 3 .   ? -37.708 33.107  22.159 1.00 46.70 ?  913  HOH A O    1 
HETATM 12293 O O    . HOH E 3 .   ? -25.961 33.673  14.997 1.00 36.84 ?  914  HOH A O    1 
HETATM 12294 O O    . HOH E 3 .   ? 4.499   1.860   30.176 1.00 30.00 ?  915  HOH A O    1 
HETATM 12295 O O    . HOH E 3 .   ? -0.914  25.559  6.454  1.00 40.93 ?  916  HOH A O    1 
HETATM 12296 O O    . HOH E 3 .   ? 0.423   -13.544 22.464 1.00 29.03 ?  917  HOH A O    1 
HETATM 12297 O O    . HOH E 3 .   ? -26.030 -2.077  43.014 1.00 31.79 ?  918  HOH A O    1 
HETATM 12298 O O    . HOH E 3 .   ? 10.874  2.166   24.449 1.00 40.33 ?  919  HOH A O    1 
HETATM 12299 O O    . HOH E 3 .   ? -3.015  14.017  3.545  1.00 32.71 ?  920  HOH A O    1 
HETATM 12300 O O    . HOH E 3 .   ? -15.380 38.590  14.787 1.00 36.82 ?  921  HOH A O    1 
HETATM 12301 O O    . HOH E 3 .   ? 8.037   -8.069  36.372 1.00 45.68 ?  922  HOH A O    1 
HETATM 12302 O O    . HOH E 3 .   ? -15.749 23.853  4.735  1.00 19.94 ?  923  HOH A O    1 
HETATM 12303 O O    . HOH E 3 .   ? 1.760   -1.324  19.250 1.00 19.82 ?  924  HOH A O    1 
HETATM 12304 O O    . HOH E 3 .   ? -6.188  -5.796  7.470  1.00 44.79 ?  925  HOH A O    1 
HETATM 12305 O O    . HOH E 3 .   ? -3.437  -2.041  9.196  1.00 43.07 ?  926  HOH A O    1 
HETATM 12306 O O    . HOH E 3 .   ? -10.532 12.411  3.687  1.00 41.55 ?  927  HOH A O    1 
HETATM 12307 O O    . HOH E 3 .   ? -12.629 28.817  34.798 1.00 37.32 ?  928  HOH A O    1 
HETATM 12308 O O    . HOH E 3 .   ? 15.421  13.839  27.546 1.00 22.36 ?  929  HOH A O    1 
HETATM 12309 O O    . HOH E 3 .   ? -17.232 15.825  1.858  1.00 30.71 ?  930  HOH A O    1 
HETATM 12310 O O    . HOH E 3 .   ? -7.368  28.893  7.696  1.00 38.81 ?  931  HOH A O    1 
HETATM 12311 O O    . HOH E 3 .   ? -32.501 13.992  16.707 1.00 41.05 ?  932  HOH A O    1 
HETATM 12312 O O    . HOH E 3 .   ? -28.584 13.742  45.865 1.00 48.59 ?  933  HOH A O    1 
HETATM 12313 O O    . HOH E 3 .   ? -11.830 10.933  4.485  1.00 37.62 ?  934  HOH A O    1 
HETATM 12314 O O    . HOH E 3 .   ? -25.950 -2.523  36.584 1.00 32.98 ?  935  HOH A O    1 
HETATM 12315 O O    . HOH E 3 .   ? 12.210  10.512  18.127 1.00 23.57 ?  936  HOH A O    1 
HETATM 12316 O O    . HOH E 3 .   ? 9.890   7.482   40.183 1.00 48.83 ?  937  HOH A O    1 
HETATM 12317 O O    . HOH E 3 .   ? -12.481 35.862  16.628 1.00 25.17 ?  938  HOH A O    1 
HETATM 12318 O O    . HOH E 3 .   ? -28.673 3.572   42.194 1.00 45.58 ?  939  HOH A O    1 
HETATM 12319 O O    . HOH E 3 .   ? -13.346 13.481  34.563 1.00 17.17 ?  940  HOH A O    1 
HETATM 12320 O O    . HOH E 3 .   ? -19.784 17.062  0.959  1.00 33.43 ?  941  HOH A O    1 
HETATM 12321 O O    . HOH E 3 .   ? -0.614  -17.675 43.314 1.00 46.14 ?  942  HOH A O    1 
HETATM 12322 O O    . HOH E 3 .   ? -38.128 19.350  21.312 1.00 34.36 ?  943  HOH A O    1 
HETATM 12323 O O    . HOH E 3 .   ? -8.866  28.552  27.359 1.00 36.31 ?  944  HOH A O    1 
HETATM 12324 O O    . HOH E 3 .   ? 12.836  7.399   15.483 1.00 37.25 ?  945  HOH A O    1 
HETATM 12325 O O    . HOH E 3 .   ? -18.121 6.487   49.080 1.00 39.78 ?  946  HOH A O    1 
HETATM 12326 O O    . HOH E 3 .   ? -34.850 28.052  19.667 1.00 21.65 ?  947  HOH A O    1 
HETATM 12327 O O    . HOH E 3 .   ? 10.408  15.778  15.510 1.00 34.21 ?  948  HOH A O    1 
HETATM 12328 O O    . HOH E 3 .   ? 11.806  17.235  18.248 1.00 38.99 ?  949  HOH A O    1 
HETATM 12329 O O    . HOH E 3 .   ? 6.346   -4.613  30.165 1.00 44.06 ?  950  HOH A O    1 
HETATM 12330 O O    . HOH E 3 .   ? -27.748 11.345  8.731  1.00 30.01 ?  951  HOH A O    1 
HETATM 12331 O O    . HOH E 3 .   ? 0.720   4.589   32.093 1.00 22.33 ?  952  HOH A O    1 
HETATM 12332 O O    . HOH E 3 .   ? -26.351 7.409   18.644 1.00 23.03 ?  953  HOH A O    1 
HETATM 12333 O O    . HOH E 3 .   ? 1.669   -5.784  25.345 1.00 32.16 ?  954  HOH A O    1 
HETATM 12334 O O    . HOH E 3 .   ? 0.243   -4.517  22.549 1.00 32.52 ?  955  HOH A O    1 
HETATM 12335 O O    . HOH E 3 .   ? -11.512 32.281  18.448 1.00 20.15 ?  956  HOH A O    1 
HETATM 12336 O O    . HOH E 3 .   ? 4.307   -2.452  29.215 1.00 35.02 ?  957  HOH A O    1 
HETATM 12337 O O    . HOH E 3 .   ? -4.047  17.250  37.250 1.00 37.15 ?  958  HOH A O    1 
HETATM 12338 O O    . HOH E 3 .   ? -8.225  34.748  16.563 1.00 35.60 ?  959  HOH A O    1 
HETATM 12339 O O    . HOH E 3 .   ? -31.310 24.804  12.235 1.00 20.14 ?  960  HOH A O    1 
HETATM 12340 O O    . HOH E 3 .   ? -16.288 37.970  22.152 1.00 34.92 ?  961  HOH A O    1 
HETATM 12341 O O    . HOH E 3 .   ? -8.833  30.755  21.577 1.00 26.96 ?  962  HOH A O    1 
HETATM 12342 O O    . HOH E 3 .   ? -9.697  22.924  8.120  1.00 15.27 ?  963  HOH A O    1 
HETATM 12343 O O    . HOH E 3 .   ? -2.599  -3.304  11.350 1.00 30.78 ?  964  HOH A O    1 
HETATM 12344 O O    . HOH E 3 .   ? 7.829   -0.605  27.713 1.00 43.80 ?  965  HOH A O    1 
HETATM 12345 O O    . HOH E 3 .   ? -15.182 17.249  31.697 1.00 12.50 ?  966  HOH A O    1 
HETATM 12346 O O    . HOH E 3 .   ? 5.707   -1.139  27.524 1.00 38.16 ?  967  HOH A O    1 
HETATM 12347 O O    . HOH E 3 .   ? -9.061  25.553  7.345  1.00 18.96 ?  968  HOH A O    1 
HETATM 12348 O O    . HOH E 3 .   ? -26.346 -2.222  22.375 1.00 44.30 ?  969  HOH A O    1 
HETATM 12349 O O    . HOH E 3 .   ? -5.772  21.120  6.850  1.00 27.99 ?  970  HOH A O    1 
HETATM 12350 O O    . HOH E 3 .   ? 4.031   4.021   9.845  1.00 42.17 ?  971  HOH A O    1 
HETATM 12351 O O    . HOH E 3 .   ? 3.127   -7.404  23.953 1.00 43.20 ?  972  HOH A O    1 
HETATM 12352 O O    . HOH E 3 .   ? -23.728 22.339  2.917  1.00 19.24 ?  973  HOH A O    1 
HETATM 12353 O O    . HOH E 3 .   ? -17.924 1.232   10.153 1.00 42.97 ?  974  HOH A O    1 
HETATM 12354 O O    . HOH E 3 .   ? -0.418  26.707  41.215 1.00 18.38 ?  975  HOH A O    1 
HETATM 12355 O O    . HOH E 3 .   ? -22.377 20.819  1.083  1.00 24.18 ?  976  HOH A O    1 
HETATM 12356 O O    . HOH E 3 .   ? -10.914 11.345  38.143 1.00 27.79 ?  977  HOH A O    1 
HETATM 12357 O O    . HOH E 3 .   ? -20.311 37.639  27.124 1.00 32.06 ?  978  HOH A O    1 
HETATM 12358 O O    . HOH E 3 .   ? 3.390   -3.391  18.752 1.00 38.71 ?  979  HOH A O    1 
HETATM 12359 O O    . HOH E 3 .   ? -35.058 6.283   34.082 1.00 48.15 ?  980  HOH A O    1 
HETATM 12360 O O    . HOH E 3 .   ? -34.327 10.068  35.721 1.00 47.91 ?  981  HOH A O    1 
HETATM 12361 O O    . HOH E 3 .   ? -26.773 -4.910  39.598 1.00 44.75 ?  982  HOH A O    1 
HETATM 12362 O O    . HOH E 3 .   ? -9.469  32.984  20.236 1.00 30.14 ?  983  HOH A O    1 
HETATM 12363 O O    . HOH E 3 .   ? 0.899   -6.462  47.010 1.00 48.39 ?  984  HOH A O    1 
HETATM 12364 O O    . HOH E 3 .   ? -28.681 31.654  17.117 1.00 42.26 ?  985  HOH A O    1 
HETATM 12365 O O    . HOH E 3 .   ? -30.569 8.814   15.924 1.00 31.49 ?  986  HOH A O    1 
HETATM 12366 O O    . HOH E 3 .   ? -25.635 30.250  29.345 1.00 28.10 ?  987  HOH A O    1 
HETATM 12367 O O    . HOH E 3 .   ? -22.634 30.900  31.809 1.00 30.63 ?  988  HOH A O    1 
HETATM 12368 O O    . HOH E 3 .   ? -35.619 16.837  16.850 1.00 33.85 ?  989  HOH A O    1 
HETATM 12369 O O    . HOH E 3 .   ? -4.164  6.215   48.907 1.00 39.97 ?  990  HOH A O    1 
HETATM 12370 O O    . HOH E 3 .   ? 9.280   -1.865  17.349 1.00 42.83 ?  991  HOH A O    1 
HETATM 12371 O O    . HOH E 3 .   ? 8.187   16.363  32.646 1.00 26.78 ?  992  HOH A O    1 
HETATM 12372 O O    . HOH E 3 .   ? 17.293  13.015  29.305 1.00 32.54 ?  993  HOH A O    1 
HETATM 12373 O O    . HOH E 3 .   ? -3.263  23.058  36.814 1.00 28.25 ?  994  HOH A O    1 
HETATM 12374 O O    . HOH E 3 .   ? -7.583  14.940  33.937 1.00 25.92 ?  995  HOH A O    1 
HETATM 12375 O O    . HOH E 3 .   ? -31.857 6.567   36.858 1.00 37.96 ?  996  HOH A O    1 
HETATM 12376 O O    . HOH E 3 .   ? -11.931 28.874  7.305  1.00 22.93 ?  997  HOH A O    1 
HETATM 12377 O O    . HOH E 3 .   ? -25.373 34.698  8.443  1.00 18.81 ?  998  HOH A O    1 
HETATM 12378 O O    . HOH E 3 .   ? -30.586 31.891  29.540 1.00 48.26 ?  999  HOH A O    1 
HETATM 12379 O O    . HOH E 3 .   ? -15.965 19.590  2.539  1.00 23.22 ?  1000 HOH A O    1 
HETATM 12380 O O    . HOH E 3 .   ? 6.999   22.807  32.541 1.00 32.07 ?  1001 HOH A O    1 
HETATM 12381 O O    . HOH E 3 .   ? 9.391   20.901  29.331 1.00 33.63 ?  1002 HOH A O    1 
HETATM 12382 O O    . HOH E 3 .   ? -3.401  2.224   8.312  1.00 36.56 ?  1003 HOH A O    1 
HETATM 12383 O O    . HOH E 3 .   ? 7.834   -1.043  22.508 1.00 42.01 ?  1004 HOH A O    1 
HETATM 12384 O O    . HOH E 3 .   ? 1.746   -2.975  21.781 1.00 38.04 ?  1005 HOH A O    1 
HETATM 12385 O O    . HOH E 3 .   ? 5.189   13.776  7.052  1.00 33.39 ?  1006 HOH A O    1 
HETATM 12386 O O    . HOH E 3 .   ? -9.886  13.485  36.447 1.00 25.31 ?  1007 HOH A O    1 
HETATM 12387 O O    . HOH E 3 .   ? -22.855 -9.005  36.574 1.00 45.44 ?  1008 HOH A O    1 
HETATM 12388 O O    . HOH E 3 .   ? -13.548 -18.410 36.364 1.00 39.30 ?  1009 HOH A O    1 
HETATM 12389 O O    . HOH E 3 .   ? -30.882 4.536   35.818 1.00 27.29 ?  1010 HOH A O    1 
HETATM 12390 O O    . HOH E 3 .   ? -2.968  -18.313 44.868 1.00 43.78 ?  1011 HOH A O    1 
HETATM 12391 O O    . HOH E 3 .   ? -3.517  18.049  8.969  1.00 28.04 ?  1012 HOH A O    1 
HETATM 12392 O O    . HOH E 3 .   ? -8.063  5.267   3.488  1.00 43.41 ?  1013 HOH A O    1 
HETATM 12393 O O    . HOH E 3 .   ? -17.839 13.301  2.189  1.00 35.57 ?  1014 HOH A O    1 
HETATM 12394 O O    . HOH E 3 .   ? -4.070  19.543  39.215 1.00 48.08 ?  1015 HOH A O    1 
HETATM 12395 O O    . HOH E 3 .   ? -36.689 18.034  23.044 1.00 21.16 ?  1016 HOH A O    1 
HETATM 12396 O O    . HOH E 3 .   ? 19.180  15.705  21.452 1.00 41.88 ?  1017 HOH A O    1 
HETATM 12397 O O    . HOH E 3 .   ? -15.944 -12.762 24.022 1.00 28.78 ?  1018 HOH A O    1 
HETATM 12398 O O    . HOH E 3 .   ? -17.954 19.283  0.508  1.00 33.24 ?  1019 HOH A O    1 
HETATM 12399 O O    . HOH E 3 .   ? -19.154 13.661  45.469 1.00 43.50 ?  1020 HOH A O    1 
HETATM 12400 O O    . HOH E 3 .   ? -27.280 -1.963  39.053 1.00 32.89 ?  1021 HOH A O    1 
HETATM 12401 O O    . HOH E 3 .   ? -5.394  19.707  9.057  1.00 33.29 ?  1022 HOH A O    1 
HETATM 12402 O O    . HOH E 3 .   ? -13.798 17.995  2.020  1.00 29.55 ?  1023 HOH A O    1 
HETATM 12403 O O    . HOH E 3 .   ? -9.176  -13.702 47.386 1.00 42.51 ?  1024 HOH A O    1 
HETATM 12404 O O    . HOH E 3 .   ? -16.732 39.980  11.269 1.00 47.73 ?  1025 HOH A O    1 
HETATM 12405 O O    . HOH E 3 .   ? -21.930 38.447  19.992 1.00 38.87 ?  1026 HOH A O    1 
HETATM 12406 O O    . HOH E 3 .   ? 9.829   -7.757  34.691 1.00 43.63 ?  1027 HOH A O    1 
HETATM 12407 O O    . HOH E 3 .   ? -26.954 -1.326  34.450 1.00 27.37 ?  1028 HOH A O    1 
HETATM 12408 O O    . HOH E 3 .   ? -34.203 10.080  21.539 1.00 37.52 ?  1029 HOH A O    1 
HETATM 12409 O O    . HOH E 3 .   ? -8.167  -14.090 44.896 1.00 32.24 ?  1030 HOH A O    1 
HETATM 12410 O O    . HOH E 3 .   ? 12.058  13.835  16.158 1.00 30.23 ?  1031 HOH A O    1 
HETATM 12411 O O    . HOH E 3 .   ? -3.445  17.776  4.631  1.00 31.71 ?  1032 HOH A O    1 
HETATM 12412 O O    . HOH E 3 .   ? 5.803   -10.730 28.243 1.00 42.38 ?  1033 HOH A O    1 
HETATM 12413 O O    . HOH E 3 .   ? -5.538  15.938  40.608 1.00 43.43 ?  1034 HOH A O    1 
HETATM 12414 O O    . HOH E 3 .   ? 2.613   -4.376  45.258 1.00 41.18 ?  1035 HOH A O    1 
HETATM 12415 O O    . HOH E 3 .   ? -2.595  6.141   5.326  1.00 38.40 ?  1036 HOH A O    1 
HETATM 12416 O O    . HOH E 3 .   ? -15.955 14.586  37.600 1.00 43.51 ?  1037 HOH A O    1 
HETATM 12417 O O    . HOH E 3 .   ? -24.287 39.810  23.751 1.00 42.97 ?  1038 HOH A O    1 
HETATM 12418 O O    . HOH E 3 .   ? -8.339  12.587  38.586 1.00 42.65 ?  1039 HOH A O    1 
HETATM 12419 O O    . HOH E 3 .   ? -2.839  -4.964  49.552 1.00 40.29 ?  1040 HOH A O    1 
HETATM 12420 O O    . HOH E 3 .   ? 8.233   16.887  11.998 1.00 28.76 ?  1041 HOH A O    1 
HETATM 12421 O O    . HOH E 3 .   ? 1.583   -3.443  24.618 1.00 41.58 ?  1042 HOH A O    1 
HETATM 12422 O O    . HOH E 3 .   ? 0.864   15.183  6.550  1.00 31.16 ?  1043 HOH A O    1 
HETATM 12423 O O    . HOH E 3 .   ? -22.091 10.052  4.516  1.00 30.51 ?  1044 HOH A O    1 
HETATM 12424 O O    . HOH E 3 .   ? -5.682  5.395   5.224  1.00 36.68 ?  1045 HOH A O    1 
HETATM 12425 O O    . HOH E 3 .   ? -27.569 -2.032  29.786 1.00 36.39 ?  1046 HOH A O    1 
HETATM 12426 O O    . HOH E 3 .   ? -7.658  30.607  24.120 1.00 45.82 ?  1047 HOH A O    1 
HETATM 12427 O O    . HOH E 3 .   ? -28.130 15.400  39.767 1.00 28.97 ?  1048 HOH A O    1 
HETATM 12428 O O    . HOH E 3 .   ? -30.456 7.830   38.839 1.00 36.28 ?  1049 HOH A O    1 
HETATM 12429 O O    . HOH E 3 .   ? -8.338  14.219  40.504 1.00 41.26 ?  1050 HOH A O    1 
HETATM 12430 O O    . HOH E 3 .   ? -35.146 19.011  26.824 1.00 18.57 ?  1051 HOH A O    1 
HETATM 12431 O O    . HOH E 3 .   ? -20.897 -14.974 33.594 1.00 40.25 ?  1052 HOH A O    1 
HETATM 12432 O O    . HOH E 3 .   ? 11.412  11.719  14.408 1.00 22.27 ?  1053 HOH A O    1 
HETATM 12433 O O    . HOH E 3 .   ? 6.088   -14.296 35.509 1.00 38.80 ?  1054 HOH A O    1 
HETATM 12434 O O    . HOH E 3 .   ? 7.931   20.628  37.629 1.00 37.68 ?  1055 HOH A O    1 
HETATM 12435 O O    . HOH E 3 .   ? -34.034 12.451  32.357 1.00 39.32 ?  1056 HOH A O    1 
HETATM 12436 O O    . HOH E 3 .   ? 3.728   -2.724  47.687 1.00 38.62 ?  1057 HOH A O    1 
HETATM 12437 O O    . HOH E 3 .   ? -13.595 24.830  33.516 1.00 22.63 ?  1058 HOH A O    1 
HETATM 12438 O O    . HOH E 3 .   ? 11.908  13.983  32.584 1.00 34.81 ?  1059 HOH A O    1 
HETATM 12439 O O    . HOH E 3 .   ? -3.221  30.159  25.982 1.00 37.80 ?  1060 HOH A O    1 
HETATM 12440 O O    . HOH E 3 .   ? 12.511  20.082  19.075 1.00 40.65 ?  1061 HOH A O    1 
HETATM 12441 O O    . HOH E 3 .   ? -31.630 13.278  37.154 1.00 44.74 ?  1062 HOH A O    1 
HETATM 12442 O O    . HOH E 3 .   ? -21.949 27.626  33.545 1.00 30.75 ?  1063 HOH A O    1 
HETATM 12443 O O    . HOH E 3 .   ? -17.839 13.159  36.028 1.00 36.69 ?  1064 HOH A O    1 
HETATM 12444 O O    . HOH E 3 .   ? -42.505 21.185  21.430 1.00 34.36 ?  1065 HOH A O    1 
HETATM 12445 O O    . HOH E 3 .   ? -4.886  -14.211 22.957 1.00 20.61 ?  1066 HOH A O    1 
HETATM 12446 O O    . HOH E 3 .   ? -32.334 29.503  18.867 1.00 33.33 ?  1067 HOH A O    1 
HETATM 12447 O O    . HOH E 3 .   ? 2.155   19.387  6.158  1.00 35.21 ?  1068 HOH A O    1 
HETATM 12448 O O    . HOH E 3 .   ? 3.027   15.279  8.166  1.00 24.17 ?  1069 HOH A O    1 
HETATM 12449 O O    . HOH E 3 .   ? -4.615  -16.415 24.567 1.00 25.62 ?  1070 HOH A O    1 
HETATM 12450 O O    . HOH E 3 .   ? 8.722   20.695  32.492 1.00 31.31 ?  1071 HOH A O    1 
HETATM 12451 O O    . HOH E 3 .   ? -8.025  8.661   3.720  1.00 27.06 ?  1072 HOH A O    1 
HETATM 12452 O O    . HOH E 3 .   ? -32.777 9.573   17.689 1.00 40.69 ?  1073 HOH A O    1 
HETATM 12453 O O    . HOH E 3 .   ? -33.281 12.628  25.433 1.00 31.14 ?  1074 HOH A O    1 
HETATM 12454 O O    . HOH E 3 .   ? -20.509 -16.190 43.756 1.00 46.40 ?  1075 HOH A O    1 
HETATM 12455 O O    . HOH E 3 .   ? -33.264 14.228  30.400 1.00 26.04 ?  1076 HOH A O    1 
HETATM 12456 O O    . HOH E 3 .   ? -19.893 21.424  0.339  1.00 23.24 ?  1077 HOH A O    1 
HETATM 12457 O O    . HOH E 3 .   ? 4.359   17.852  7.996  1.00 29.76 ?  1078 HOH A O    1 
HETATM 12458 O O    . HOH E 3 .   ? 9.254   14.419  33.747 1.00 39.46 ?  1079 HOH A O    1 
HETATM 12459 O O    . HOH E 3 .   ? -34.849 14.839  24.872 1.00 21.52 ?  1080 HOH A O    1 
HETATM 12460 O O    . HOH E 3 .   ? -1.152  22.542  40.791 1.00 35.04 ?  1081 HOH A O    1 
HETATM 12461 O O    . HOH E 3 .   ? -16.082 22.307  2.539  1.00 21.44 ?  1082 HOH A O    1 
HETATM 12462 O O    . HOH E 3 .   ? -4.171  6.664   2.766  1.00 53.44 ?  1083 HOH A O    1 
HETATM 12463 O O    . HOH E 3 .   ? -13.200 24.378  5.585  1.00 17.65 ?  1084 HOH A O    1 
HETATM 12464 O O    . HOH E 3 .   ? 6.690   19.525  39.917 1.00 33.48 ?  1085 HOH A O    1 
HETATM 12465 O O    . HOH E 3 .   ? -2.367  25.410  48.714 1.00 50.63 ?  1086 HOH A O    1 
HETATM 12466 O O    . HOH E 3 .   ? -16.687 35.766  17.930 1.00 22.34 ?  1087 HOH A O    1 
HETATM 12467 O O    . HOH E 3 .   ? 5.051   9.385   5.368  1.00 35.33 ?  1088 HOH A O    1 
HETATM 12468 O O    . HOH E 3 .   ? 7.071   -10.896 37.691 1.00 40.03 ?  1089 HOH A O    1 
HETATM 12469 O O    . HOH E 3 .   ? 17.054  17.258  18.548 1.00 41.56 ?  1090 HOH A O    1 
HETATM 12470 O O    . HOH E 3 .   ? -5.976  20.594  34.579 1.00 40.53 ?  1091 HOH A O    1 
HETATM 12471 O O    . HOH E 3 .   ? 16.201  16.352  26.864 1.00 23.17 ?  1092 HOH A O    1 
HETATM 12472 O O    . HOH E 3 .   ? 6.299   17.622  52.109 1.00 43.91 ?  1093 HOH A O    1 
HETATM 12473 O O    . HOH E 3 .   ? 1.858   14.155  4.168  1.00 40.69 ?  1094 HOH A O    1 
HETATM 12474 O O    . HOH E 3 .   ? -6.795  18.529  33.886 1.00 41.95 ?  1095 HOH A O    1 
HETATM 12475 O O    . HOH E 3 .   ? -14.976 16.229  0.449  1.00 39.41 ?  1096 HOH A O    1 
HETATM 12476 O O    . HOH E 3 .   ? -15.031 34.325  19.974 1.00 22.03 ?  1097 HOH A O    1 
HETATM 12477 O O    . HOH E 3 .   ? -22.104 -14.273 25.266 1.00 32.94 ?  1098 HOH A O    1 
HETATM 12478 O O    . HOH E 3 .   ? 15.736  17.337  24.430 1.00 21.42 ?  1099 HOH A O    1 
HETATM 12479 O O    . HOH E 3 .   ? -11.537 17.317  33.182 1.00 16.89 ?  1100 HOH A O    1 
HETATM 12480 O O    . HOH E 3 .   ? -1.814  18.284  6.806  1.00 26.02 ?  1101 HOH A O    1 
HETATM 12481 O O    . HOH E 3 .   ? -9.291  10.776  2.435  1.00 42.28 ?  1102 HOH A O    1 
HETATM 12482 O O    . HOH E 3 .   ? -7.658  12.882  1.766  1.00 47.73 ?  1103 HOH A O    1 
HETATM 12483 O O    . HOH E 3 .   ? -35.700 16.379  26.938 1.00 20.89 ?  1104 HOH A O    1 
HETATM 12484 O O    . HOH E 3 .   ? -32.837 3.439   35.736 1.00 40.68 ?  1105 HOH A O    1 
HETATM 12485 O O    . HOH E 3 .   ? 0.241   17.252  6.227  1.00 40.78 ?  1106 HOH A O    1 
HETATM 12486 O O    . HOH E 3 .   ? -1.163  -1.072  7.772  1.00 44.56 ?  1107 HOH A O    1 
HETATM 12487 O O    . HOH E 3 .   ? -15.205 22.764  34.529 1.00 23.45 ?  1108 HOH A O    1 
HETATM 12488 O O    . HOH E 3 .   ? -35.380 15.140  29.266 1.00 29.80 ?  1109 HOH A O    1 
HETATM 12489 O O    . HOH E 3 .   ? -2.237  25.136  40.474 1.00 27.45 ?  1110 HOH A O    1 
HETATM 12490 O O    . HOH E 3 .   ? -5.793  22.180  36.761 1.00 36.93 ?  1111 HOH A O    1 
HETATM 12491 O O    . HOH E 3 .   ? -14.097 17.827  34.187 1.00 16.91 ?  1112 HOH A O    1 
HETATM 12492 O O    . HOH E 3 .   ? -13.662 -19.623 38.805 1.00 49.18 ?  1113 HOH A O    1 
HETATM 12493 O O    . HOH E 3 .   ? -6.743  27.878  28.431 1.00 29.71 ?  1114 HOH A O    1 
HETATM 12494 O O    . HOH E 3 .   ? -16.689 38.148  19.246 1.00 30.66 ?  1115 HOH A O    1 
HETATM 12495 O O    . HOH E 3 .   ? 2.547   33.981  24.767 1.00 40.48 ?  1116 HOH A O    1 
HETATM 12496 O O    . HOH E 3 .   ? -4.785  23.056  43.521 1.00 33.93 ?  1117 HOH A O    1 
HETATM 12497 O O    . HOH E 3 .   ? -12.842 35.860  19.490 1.00 26.98 ?  1118 HOH A O    1 
HETATM 12498 O O    . HOH E 3 .   ? 5.139   -6.016  22.944 1.00 48.11 ?  1119 HOH A O    1 
HETATM 12499 O O    . HOH E 3 .   ? -9.504  17.243  34.982 1.00 29.54 ?  1120 HOH A O    1 
HETATM 12500 O O    . HOH E 3 .   ? -4.352  25.591  42.402 1.00 23.27 ?  1121 HOH A O    1 
HETATM 12501 O O    . HOH E 3 .   ? -11.072 15.792  37.126 1.00 38.59 ?  1122 HOH A O    1 
HETATM 12502 O O    . HOH E 3 .   ? -6.759  25.707  41.016 1.00 35.95 ?  1123 HOH A O    1 
HETATM 12503 O O    . HOH E 3 .   ? -11.307 20.694  35.958 1.00 35.08 ?  1124 HOH A O    1 
HETATM 12504 O O    . HOH F 3 .   ? -20.839 21.090  49.107 1.00 39.81 ?  401  HOH B O    1 
HETATM 12505 O O    . HOH F 3 .   ? -29.949 25.523  35.928 1.00 42.92 ?  402  HOH B O    1 
HETATM 12506 O O    . HOH F 3 .   ? -4.959  56.754  42.521 1.00 7.69  ?  403  HOH B O    1 
HETATM 12507 O O    . HOH F 3 .   ? -10.065 55.345  59.143 1.00 43.64 ?  404  HOH B O    1 
HETATM 12508 O O    . HOH F 3 .   ? -22.938 29.399  39.743 1.00 44.45 ?  405  HOH B O    1 
HETATM 12509 O O    . HOH F 3 .   ? -31.756 33.477  57.523 1.00 35.17 ?  406  HOH B O    1 
HETATM 12510 O O    . HOH F 3 .   ? -13.200 24.204  52.141 1.00 37.54 ?  407  HOH B O    1 
HETATM 12511 O O    . HOH F 3 .   ? 5.281   28.686  60.792 1.00 7.81  ?  408  HOH B O    1 
HETATM 12512 O O    . HOH F 3 .   ? 14.562  26.825  25.006 1.00 33.74 ?  409  HOH B O    1 
HETATM 12513 O O    . HOH F 3 .   ? -13.359 26.251  52.960 1.00 32.90 ?  410  HOH B O    1 
HETATM 12514 O O    . HOH F 3 .   ? -28.033 52.282  38.432 1.00 38.43 ?  411  HOH B O    1 
HETATM 12515 O O    . HOH F 3 .   ? -9.533  38.579  24.705 1.00 30.73 ?  412  HOH B O    1 
HETATM 12516 O O    . HOH F 3 .   ? 12.071  31.830  58.512 1.00 18.69 ?  413  HOH B O    1 
HETATM 12517 O O    . HOH F 3 .   ? 10.474  38.557  20.892 1.00 31.78 ?  414  HOH B O    1 
HETATM 12518 O O    . HOH F 3 .   ? -28.485 42.832  49.830 1.00 44.09 ?  415  HOH B O    1 
HETATM 12519 O O    . HOH F 3 .   ? 15.710  25.600  48.280 1.00 32.20 ?  416  HOH B O    1 
HETATM 12520 O O    . HOH F 3 .   ? -32.473 22.996  50.945 1.00 39.24 ?  417  HOH B O    1 
HETATM 12521 O O    . HOH F 3 .   ? -0.295  53.388  57.600 1.00 22.17 ?  418  HOH B O    1 
HETATM 12522 O O    . HOH F 3 .   ? -18.518 37.411  52.564 1.00 28.84 ?  419  HOH B O    1 
HETATM 12523 O O    . HOH F 3 .   ? -10.402 49.997  25.538 1.00 35.67 ?  420  HOH B O    1 
HETATM 12524 O O    . HOH F 3 .   ? -33.929 29.188  40.020 1.00 21.25 ?  421  HOH B O    1 
HETATM 12525 O O    . HOH F 3 .   ? 10.360  24.310  52.237 1.00 26.74 ?  422  HOH B O    1 
HETATM 12526 O O    . HOH F 3 .   ? 19.325  40.012  43.361 1.00 23.80 ?  423  HOH B O    1 
HETATM 12527 O O    . HOH F 3 .   ? -5.453  16.709  57.111 1.00 36.62 ?  424  HOH B O    1 
HETATM 12528 O O    . HOH F 3 .   ? -23.564 31.903  70.453 1.00 26.13 ?  425  HOH B O    1 
HETATM 12529 O O    . HOH F 3 .   ? 19.944  33.984  29.346 1.00 37.13 ?  426  HOH B O    1 
HETATM 12530 O O    . HOH F 3 .   ? 18.203  29.626  47.305 1.00 22.23 ?  427  HOH B O    1 
HETATM 12531 O O    . HOH F 3 .   ? -32.029 20.791  42.019 1.00 34.20 ?  428  HOH B O    1 
HETATM 12532 O O    . HOH F 3 .   ? 11.785  35.974  39.308 1.00 27.34 ?  429  HOH B O    1 
HETATM 12533 O O    . HOH F 3 .   ? 5.426   42.402  61.483 1.00 34.25 ?  430  HOH B O    1 
HETATM 12534 O O    . HOH F 3 .   ? -11.944 56.203  53.942 1.00 35.70 ?  431  HOH B O    1 
HETATM 12535 O O    . HOH F 3 .   ? -30.942 32.209  54.697 1.00 29.85 ?  432  HOH B O    1 
HETATM 12536 O O    . HOH F 3 .   ? 15.934  43.490  25.743 1.00 41.10 ?  433  HOH B O    1 
HETATM 12537 O O    . HOH F 3 .   ? -31.638 28.254  37.935 1.00 46.30 ?  434  HOH B O    1 
HETATM 12538 O O    . HOH F 3 .   ? -2.985  60.714  53.173 1.00 37.87 ?  435  HOH B O    1 
HETATM 12539 O O    . HOH F 3 .   ? -30.309 36.301  52.263 1.00 40.78 ?  436  HOH B O    1 
HETATM 12540 O O    . HOH F 3 .   ? -3.381  52.346  66.022 1.00 36.68 ?  437  HOH B O    1 
HETATM 12541 O O    . HOH F 3 .   ? 17.136  49.602  39.085 1.00 36.83 ?  438  HOH B O    1 
HETATM 12542 O O    . HOH F 3 .   ? 0.099   28.173  25.449 1.00 28.41 ?  439  HOH B O    1 
HETATM 12543 O O    . HOH F 3 .   ? -9.396  18.198  57.193 1.00 39.11 ?  440  HOH B O    1 
HETATM 12544 O O    . HOH F 3 .   ? 17.966  46.806  40.515 1.00 38.90 ?  441  HOH B O    1 
HETATM 12545 O O    . HOH F 3 .   ? -27.034 17.701  43.193 1.00 45.18 ?  442  HOH B O    1 
HETATM 12546 O O    . HOH F 3 .   ? 12.686  34.926  54.391 1.00 30.61 ?  443  HOH B O    1 
HETATM 12547 O O    . HOH F 3 .   ? -0.153  46.816  35.041 1.00 16.43 ?  444  HOH B O    1 
HETATM 12548 O O    . HOH F 3 .   ? 9.727   22.638  50.125 1.00 26.41 ?  445  HOH B O    1 
HETATM 12549 O O    . HOH F 3 .   ? -29.798 40.319  37.969 1.00 40.83 ?  446  HOH B O    1 
HETATM 12550 O O    . HOH F 3 .   ? -4.486  43.245  37.617 1.00 12.10 ?  447  HOH B O    1 
HETATM 12551 O O    . HOH F 3 .   ? -27.365 42.280  45.472 1.00 36.66 ?  448  HOH B O    1 
HETATM 12552 O O    . HOH F 3 .   ? -26.352 56.544  44.421 1.00 41.63 ?  449  HOH B O    1 
HETATM 12553 O O    . HOH F 3 .   ? 14.043  45.558  52.272 1.00 25.49 ?  450  HOH B O    1 
HETATM 12554 O O    . HOH F 3 .   ? -10.991 20.931  62.366 1.00 29.27 ?  451  HOH B O    1 
HETATM 12555 O O    . HOH F 3 .   ? -16.028 46.157  23.270 1.00 23.53 ?  452  HOH B O    1 
HETATM 12556 O O    . HOH F 3 .   ? -18.200 32.094  33.851 1.00 15.10 ?  453  HOH B O    1 
HETATM 12557 O O    . HOH F 3 .   ? 10.784  40.845  60.185 1.00 41.98 ?  454  HOH B O    1 
HETATM 12558 O O    . HOH F 3 .   ? -5.005  37.037  33.606 1.00 16.71 ?  455  HOH B O    1 
HETATM 12559 O O    . HOH F 3 .   ? 16.331  34.199  53.509 1.00 35.10 ?  456  HOH B O    1 
HETATM 12560 O O    . HOH F 3 .   ? 3.220   18.379  61.250 1.00 25.45 ?  457  HOH B O    1 
HETATM 12561 O O    . HOH F 3 .   ? -8.652  27.596  78.598 1.00 33.51 ?  458  HOH B O    1 
HETATM 12562 O O    . HOH F 3 .   ? -23.463 40.185  73.312 1.00 28.16 ?  459  HOH B O    1 
HETATM 12563 O O    . HOH F 3 .   ? -6.437  58.615  50.605 1.00 30.36 ?  460  HOH B O    1 
HETATM 12564 O O    . HOH F 3 .   ? -26.844 31.042  43.165 1.00 27.45 ?  461  HOH B O    1 
HETATM 12565 O O    . HOH F 3 .   ? -29.860 25.688  37.875 1.00 50.38 ?  462  HOH B O    1 
HETATM 12566 O O    . HOH F 3 .   ? -21.756 49.334  65.542 1.00 31.13 ?  463  HOH B O    1 
HETATM 12567 O O    . HOH F 3 .   ? -22.833 44.023  56.115 1.00 17.51 ?  464  HOH B O    1 
HETATM 12568 O O    . HOH F 3 .   ? 1.034   48.461  25.291 1.00 36.05 ?  465  HOH B O    1 
HETATM 12569 O O    . HOH F 3 .   ? -20.253 48.992  33.357 1.00 24.12 ?  466  HOH B O    1 
HETATM 12570 O O    . HOH F 3 .   ? -15.722 37.392  43.242 1.00 15.90 ?  467  HOH B O    1 
HETATM 12571 O O    . HOH F 3 .   ? -23.951 41.441  60.068 1.00 17.01 ?  468  HOH B O    1 
HETATM 12572 O O    . HOH F 3 .   ? 3.704   30.859  27.039 1.00 25.51 ?  469  HOH B O    1 
HETATM 12573 O O    . HOH F 3 .   ? 4.148   56.527  38.283 1.00 31.28 ?  470  HOH B O    1 
HETATM 12574 O O    . HOH F 3 .   ? 11.789  27.684  59.800 1.00 28.92 ?  471  HOH B O    1 
HETATM 12575 O O    . HOH F 3 .   ? -8.508  40.317  67.299 1.00 15.76 ?  472  HOH B O    1 
HETATM 12576 O O    . HOH F 3 .   ? 0.930   14.453  61.103 1.00 38.51 ?  473  HOH B O    1 
HETATM 12577 O O    . HOH F 3 .   ? 3.410   59.848  52.132 1.00 30.44 ?  474  HOH B O    1 
HETATM 12578 O O    . HOH F 3 .   ? -22.623 38.369  35.173 1.00 25.26 ?  475  HOH B O    1 
HETATM 12579 O O    . HOH F 3 .   ? -13.057 24.607  56.704 1.00 23.53 ?  476  HOH B O    1 
HETATM 12580 O O    . HOH F 3 .   ? 15.477  40.502  25.659 1.00 29.83 ?  477  HOH B O    1 
HETATM 12581 O O    . HOH F 3 .   ? -18.027 51.156  29.093 1.00 20.85 ?  478  HOH B O    1 
HETATM 12582 O O    . HOH F 3 .   ? -17.591 34.181  44.711 1.00 11.88 ?  479  HOH B O    1 
HETATM 12583 O O    . HOH F 3 .   ? -19.603 46.931  58.041 1.00 18.34 ?  480  HOH B O    1 
HETATM 12584 O O    . HOH F 3 .   ? -29.071 33.476  51.903 1.00 25.53 ?  481  HOH B O    1 
HETATM 12585 O O    . HOH F 3 .   ? -19.001 21.330  69.068 1.00 30.82 ?  482  HOH B O    1 
HETATM 12586 O O    . HOH F 3 .   ? -8.331  55.200  37.847 1.00 14.67 ?  483  HOH B O    1 
HETATM 12587 O O    . HOH F 3 .   ? -22.532 40.066  49.678 1.00 23.07 ?  484  HOH B O    1 
HETATM 12588 O O    . HOH F 3 .   ? -2.770  17.226  57.668 1.00 32.20 ?  485  HOH B O    1 
HETATM 12589 O O    . HOH F 3 .   ? -1.730  23.896  29.864 1.00 16.10 ?  486  HOH B O    1 
HETATM 12590 O O    . HOH F 3 .   ? -27.754 29.408  60.850 1.00 22.67 ?  487  HOH B O    1 
HETATM 12591 O O    . HOH F 3 .   ? -23.687 15.327  37.351 1.00 22.80 ?  488  HOH B O    1 
HETATM 12592 O O    . HOH F 3 .   ? 20.049  38.914  36.853 1.00 24.15 ?  489  HOH B O    1 
HETATM 12593 O O    . HOH F 3 .   ? -10.380 34.917  30.354 1.00 21.67 ?  490  HOH B O    1 
HETATM 12594 O O    . HOH F 3 .   ? 4.298   38.738  24.478 1.00 27.94 ?  491  HOH B O    1 
HETATM 12595 O O    . HOH F 3 .   ? 10.533  52.113  37.421 1.00 21.97 ?  492  HOH B O    1 
HETATM 12596 O O    . HOH F 3 .   ? 6.557   44.074  21.429 1.00 31.33 ?  493  HOH B O    1 
HETATM 12597 O O    . HOH F 3 .   ? 4.867   47.863  20.266 1.00 39.82 ?  494  HOH B O    1 
HETATM 12598 O O    . HOH F 3 .   ? -15.977 56.591  33.303 1.00 30.02 ?  495  HOH B O    1 
HETATM 12599 O O    . HOH F 3 .   ? 14.980  30.064  61.402 1.00 33.35 ?  496  HOH B O    1 
HETATM 12600 O O    . HOH F 3 .   ? 0.651   45.987  32.539 1.00 14.84 ?  497  HOH B O    1 
HETATM 12601 O O    . HOH F 3 .   ? 2.381   52.380  32.490 1.00 28.19 ?  498  HOH B O    1 
HETATM 12602 O O    . HOH F 3 .   ? 1.660   39.347  33.385 1.00 12.79 ?  499  HOH B O    1 
HETATM 12603 O O    . HOH F 3 .   ? -28.405 43.445  43.035 1.00 31.82 ?  500  HOH B O    1 
HETATM 12604 O O    . HOH F 3 .   ? -0.681  50.559  57.671 1.00 18.42 ?  501  HOH B O    1 
HETATM 12605 O O    . HOH F 3 .   ? 0.319   49.194  66.046 1.00 31.20 ?  502  HOH B O    1 
HETATM 12606 O O    . HOH F 3 .   ? -0.726  22.383  69.460 1.00 16.53 ?  503  HOH B O    1 
HETATM 12607 O O    . HOH F 3 .   ? -6.481  57.195  46.205 1.00 19.25 ?  504  HOH B O    1 
HETATM 12608 O O    . HOH F 3 .   ? 13.020  33.120  52.380 1.00 21.57 ?  505  HOH B O    1 
HETATM 12609 O O    . HOH F 3 .   ? -13.376 24.549  75.788 1.00 21.95 ?  506  HOH B O    1 
HETATM 12610 O O    . HOH F 3 .   ? -5.273  30.656  67.971 1.00 20.98 ?  507  HOH B O    1 
HETATM 12611 O O    . HOH F 3 .   ? -7.085  47.867  25.833 1.00 19.31 ?  508  HOH B O    1 
HETATM 12612 O O    . HOH F 3 .   ? 19.686  31.140  31.971 1.00 27.48 ?  509  HOH B O    1 
HETATM 12613 O O    . HOH F 3 .   ? -13.125 56.228  51.570 1.00 24.52 ?  510  HOH B O    1 
HETATM 12614 O O    . HOH F 3 .   ? 18.563  30.399  36.341 1.00 30.25 ?  511  HOH B O    1 
HETATM 12615 O O    . HOH F 3 .   ? -31.639 23.684  39.748 1.00 35.00 ?  512  HOH B O    1 
HETATM 12616 O O    . HOH F 3 .   ? 2.046   44.326  62.654 1.00 33.99 ?  513  HOH B O    1 
HETATM 12617 O O    . HOH F 3 .   ? -34.626 26.901  52.253 1.00 28.85 ?  514  HOH B O    1 
HETATM 12618 O O    . HOH F 3 .   ? -12.066 37.416  33.787 1.00 14.63 ?  515  HOH B O    1 
HETATM 12619 O O    . HOH F 3 .   ? -10.692 52.331  30.004 1.00 18.99 ?  516  HOH B O    1 
HETATM 12620 O O    . HOH F 3 .   ? -28.436 18.778  36.497 1.00 21.59 ?  517  HOH B O    1 
HETATM 12621 O O    . HOH F 3 .   ? -2.117  37.935  27.091 1.00 19.36 ?  518  HOH B O    1 
HETATM 12622 O O    . HOH F 3 .   ? -1.587  17.015  67.095 1.00 35.57 ?  519  HOH B O    1 
HETATM 12623 O O    . HOH F 3 .   ? -26.739 42.396  36.387 1.00 21.36 ?  520  HOH B O    1 
HETATM 12624 O O    . HOH F 3 .   ? -30.173 21.911  54.926 1.00 33.68 ?  521  HOH B O    1 
HETATM 12625 O O    . HOH F 3 .   ? -22.203 50.734  34.490 1.00 24.24 ?  522  HOH B O    1 
HETATM 12626 O O    . HOH F 3 .   ? -12.222 24.135  59.337 1.00 22.71 ?  523  HOH B O    1 
HETATM 12627 O O    . HOH F 3 .   ? -18.190 51.375  49.409 1.00 27.11 ?  524  HOH B O    1 
HETATM 12628 O O    . HOH F 3 .   ? 11.183  30.430  45.837 1.00 14.17 ?  525  HOH B O    1 
HETATM 12629 O O    . HOH F 3 .   ? -19.860 14.627  34.405 1.00 15.53 ?  526  HOH B O    1 
HETATM 12630 O O    . HOH F 3 .   ? -19.646 35.675  74.277 1.00 39.80 ?  527  HOH B O    1 
HETATM 12631 O O    . HOH F 3 .   ? 0.191   33.797  45.160 1.00 13.01 ?  528  HOH B O    1 
HETATM 12632 O O    . HOH F 3 .   ? -7.930  34.938  31.548 1.00 20.18 ?  529  HOH B O    1 
HETATM 12633 O O    . HOH F 3 .   ? 4.762   35.286  28.150 1.00 20.55 ?  530  HOH B O    1 
HETATM 12634 O O    . HOH F 3 .   ? -10.422 47.212  66.564 1.00 19.97 ?  531  HOH B O    1 
HETATM 12635 O O    . HOH F 3 .   ? -15.986 54.562  58.018 1.00 27.81 ?  532  HOH B O    1 
HETATM 12636 O O    . HOH F 3 .   ? -0.554  57.110  35.685 1.00 23.60 ?  533  HOH B O    1 
HETATM 12637 O O    . HOH F 3 .   ? 0.595   24.041  66.459 1.00 20.65 ?  534  HOH B O    1 
HETATM 12638 O O    . HOH F 3 .   ? -25.117 38.418  75.614 1.00 40.61 ?  535  HOH B O    1 
HETATM 12639 O O    . HOH F 3 .   ? 24.752  30.430  39.501 1.00 30.90 ?  536  HOH B O    1 
HETATM 12640 O O    . HOH F 3 .   ? 24.057  28.480  33.118 1.00 33.18 ?  537  HOH B O    1 
HETATM 12641 O O    . HOH F 3 .   ? 5.469   32.460  66.120 1.00 15.79 ?  538  HOH B O    1 
HETATM 12642 O O    . HOH F 3 .   ? -23.993 50.836  45.575 1.00 21.68 ?  539  HOH B O    1 
HETATM 12643 O O    . HOH F 3 .   ? -6.614  30.928  45.794 1.00 15.20 ?  540  HOH B O    1 
HETATM 12644 O O    . HOH F 3 .   ? -4.638  40.393  33.091 1.00 13.84 ?  541  HOH B O    1 
HETATM 12645 O O    . HOH F 3 .   ? 2.900   38.767  28.735 1.00 20.21 ?  542  HOH B O    1 
HETATM 12646 O O    . HOH F 3 .   ? -8.709  54.292  62.923 1.00 29.96 ?  543  HOH B O    1 
HETATM 12647 O O    . HOH F 3 .   ? 9.610   31.826  33.136 1.00 14.44 ?  544  HOH B O    1 
HETATM 12648 O O    . HOH F 3 .   ? -20.386 49.672  52.520 1.00 35.01 ?  545  HOH B O    1 
HETATM 12649 O O    . HOH F 3 .   ? -20.515 35.942  50.112 1.00 22.40 ?  546  HOH B O    1 
HETATM 12650 O O    . HOH F 3 .   ? -16.663 14.884  31.913 1.00 13.34 ?  547  HOH B O    1 
HETATM 12651 O O    . HOH F 3 .   ? 16.452  34.208  33.603 1.00 19.42 ?  548  HOH B O    1 
HETATM 12652 O O    . HOH F 3 .   ? -25.239 25.940  42.116 1.00 27.30 ?  549  HOH B O    1 
HETATM 12653 O O    . HOH F 3 .   ? -21.929 17.400  35.540 1.00 26.10 ?  550  HOH B O    1 
HETATM 12654 O O    . HOH F 3 .   ? -23.096 22.631  56.881 1.00 33.35 ?  551  HOH B O    1 
HETATM 12655 O O    . HOH F 3 .   ? -24.706 27.318  62.945 1.00 24.26 ?  552  HOH B O    1 
HETATM 12656 O O    . HOH F 3 .   ? -13.021 21.188  70.749 1.00 22.20 ?  553  HOH B O    1 
HETATM 12657 O O    . HOH F 3 .   ? -0.123  26.894  54.132 1.00 14.53 ?  554  HOH B O    1 
HETATM 12658 O O    . HOH F 3 .   ? -2.631  43.175  71.052 1.00 45.24 ?  555  HOH B O    1 
HETATM 12659 O O    . HOH F 3 .   ? -0.524  43.107  67.716 1.00 21.26 ?  556  HOH B O    1 
HETATM 12660 O O    . HOH F 3 .   ? -9.787  38.476  68.950 1.00 19.59 ?  557  HOH B O    1 
HETATM 12661 O O    . HOH F 3 .   ? -20.555 56.945  50.056 1.00 39.71 ?  558  HOH B O    1 
HETATM 12662 O O    . HOH F 3 .   ? 14.190  23.772  35.347 1.00 24.59 ?  559  HOH B O    1 
HETATM 12663 O O    . HOH F 3 .   ? 1.647   57.278  47.173 1.00 16.68 ?  560  HOH B O    1 
HETATM 12664 O O    . HOH F 3 .   ? 16.865  23.076  40.677 1.00 35.18 ?  561  HOH B O    1 
HETATM 12665 O O    . HOH F 3 .   ? -14.279 52.374  51.808 1.00 15.15 ?  562  HOH B O    1 
HETATM 12666 O O    . HOH F 3 .   ? 0.204   44.243  23.555 1.00 27.06 ?  563  HOH B O    1 
HETATM 12667 O O    . HOH F 3 .   ? -2.620  34.104  52.562 1.00 12.54 ?  564  HOH B O    1 
HETATM 12668 O O    . HOH F 3 .   ? -28.003 21.905  44.891 1.00 31.22 ?  565  HOH B O    1 
HETATM 12669 O O    . HOH F 3 .   ? -11.306 45.440  69.902 1.00 28.26 ?  566  HOH B O    1 
HETATM 12670 O O    . HOH F 3 .   ? -7.843  44.628  60.980 1.00 13.95 ?  567  HOH B O    1 
HETATM 12671 O O    . HOH F 3 .   ? -8.869  30.591  52.905 1.00 14.59 ?  568  HOH B O    1 
HETATM 12672 O O    . HOH F 3 .   ? -15.464 27.624  44.412 1.00 26.05 ?  569  HOH B O    1 
HETATM 12673 O O    . HOH F 3 .   ? -17.569 49.525  32.983 1.00 20.08 ?  570  HOH B O    1 
HETATM 12674 O O    . HOH F 3 .   ? -9.680  31.802  49.386 1.00 15.04 ?  571  HOH B O    1 
HETATM 12675 O O    . HOH F 3 .   ? -21.313 43.602  29.827 1.00 33.27 ?  572  HOH B O    1 
HETATM 12676 O O    . HOH F 3 .   ? 0.790   39.036  35.990 1.00 13.63 ?  573  HOH B O    1 
HETATM 12677 O O    . HOH F 3 .   ? -26.635 33.061  61.890 1.00 16.94 ?  574  HOH B O    1 
HETATM 12678 O O    . HOH F 3 .   ? 16.276  29.174  25.053 1.00 34.36 ?  575  HOH B O    1 
HETATM 12679 O O    . HOH F 3 .   ? -18.660 37.754  30.748 1.00 21.44 ?  576  HOH B O    1 
HETATM 12680 O O    . HOH F 3 .   ? 3.640   52.301  52.545 1.00 17.82 ?  577  HOH B O    1 
HETATM 12681 O O    . HOH F 3 .   ? -26.121 34.661  43.934 1.00 26.98 ?  578  HOH B O    1 
HETATM 12682 O O    . HOH F 3 .   ? 1.571   54.213  59.350 1.00 29.19 ?  579  HOH B O    1 
HETATM 12683 O O    . HOH F 3 .   ? 1.479   55.777  42.282 1.00 21.36 ?  580  HOH B O    1 
HETATM 12684 O O    . HOH F 3 .   ? -17.909 39.745  51.028 1.00 13.68 ?  581  HOH B O    1 
HETATM 12685 O O    . HOH F 3 .   ? 0.051   49.594  34.573 1.00 16.75 ?  582  HOH B O    1 
HETATM 12686 O O    . HOH F 3 .   ? -28.475 41.210  65.695 1.00 21.68 ?  583  HOH B O    1 
HETATM 12687 O O    . HOH F 3 .   ? 10.685  34.853  61.534 1.00 28.92 ?  584  HOH B O    1 
HETATM 12688 O O    . HOH F 3 .   ? 13.461  41.981  54.506 1.00 36.44 ?  585  HOH B O    1 
HETATM 12689 O O    . HOH F 3 .   ? -10.202 24.838  52.566 1.00 34.43 ?  586  HOH B O    1 
HETATM 12690 O O    . HOH F 3 .   ? -11.106 54.905  57.660 1.00 29.61 ?  587  HOH B O    1 
HETATM 12691 O O    . HOH F 3 .   ? 16.175  35.337  31.078 1.00 23.44 ?  588  HOH B O    1 
HETATM 12692 O O    . HOH F 3 .   ? -2.222  28.361  71.475 1.00 21.26 ?  589  HOH B O    1 
HETATM 12693 O O    . HOH F 3 .   ? 17.792  26.383  26.011 1.00 18.86 ?  590  HOH B O    1 
HETATM 12694 O O    . HOH F 3 .   ? -32.286 30.367  56.206 1.00 44.32 ?  591  HOH B O    1 
HETATM 12695 O O    . HOH F 3 .   ? -20.527 29.426  34.870 1.00 18.94 ?  592  HOH B O    1 
HETATM 12696 O O    . HOH F 3 .   ? 10.207  54.335  45.919 1.00 22.63 ?  593  HOH B O    1 
HETATM 12697 O O    . HOH F 3 .   ? -10.043 41.544  75.568 1.00 36.56 ?  594  HOH B O    1 
HETATM 12698 O O    . HOH F 3 .   ? -6.706  54.980  49.703 1.00 19.64 ?  595  HOH B O    1 
HETATM 12699 O O    . HOH F 3 .   ? 20.299  33.740  35.527 1.00 33.55 ?  596  HOH B O    1 
HETATM 12700 O O    . HOH F 3 .   ? -7.296  42.693  22.933 1.00 40.53 ?  597  HOH B O    1 
HETATM 12701 O O    . HOH F 3 .   ? 1.056   52.540  51.815 1.00 18.59 ?  598  HOH B O    1 
HETATM 12702 O O    . HOH F 3 .   ? -32.873 34.741  60.755 1.00 40.76 ?  599  HOH B O    1 
HETATM 12703 O O    . HOH F 3 .   ? -1.390  54.553  53.421 1.00 19.43 ?  600  HOH B O    1 
HETATM 12704 O O    . HOH F 3 .   ? -4.979  60.634  40.503 1.00 32.74 ?  601  HOH B O    1 
HETATM 12705 O O    . HOH F 3 .   ? -31.889 23.048  43.760 1.00 24.12 ?  602  HOH B O    1 
HETATM 12706 O O    . HOH F 3 .   ? -19.805 52.655  62.571 1.00 29.45 ?  603  HOH B O    1 
HETATM 12707 O O    . HOH F 3 .   ? -18.498 43.452  25.712 1.00 27.14 ?  604  HOH B O    1 
HETATM 12708 O O    . HOH F 3 .   ? -27.765 31.971  64.153 1.00 20.11 ?  605  HOH B O    1 
HETATM 12709 O O    . HOH F 3 .   ? 8.854   23.370  40.882 1.00 25.15 ?  606  HOH B O    1 
HETATM 12710 O O    . HOH F 3 .   ? -7.167  47.389  63.659 1.00 17.85 ?  607  HOH B O    1 
HETATM 12711 O O    . HOH F 3 .   ? -3.285  55.096  55.386 1.00 17.73 ?  608  HOH B O    1 
HETATM 12712 O O    . HOH F 3 .   ? 0.930   19.245  68.328 1.00 17.92 ?  609  HOH B O    1 
HETATM 12713 O O    . HOH F 3 .   ? -3.785  36.452  69.902 1.00 26.37 ?  610  HOH B O    1 
HETATM 12714 O O    . HOH F 3 .   ? -10.267 55.088  35.861 1.00 15.30 ?  611  HOH B O    1 
HETATM 12715 O O    . HOH F 3 .   ? 18.466  36.360  49.364 1.00 31.75 ?  612  HOH B O    1 
HETATM 12716 O O    . HOH F 3 .   ? -1.716  60.683  40.948 1.00 25.66 ?  613  HOH B O    1 
HETATM 12717 O O    . HOH F 3 .   ? 12.804  27.659  63.550 1.00 18.49 ?  614  HOH B O    1 
HETATM 12718 O O    . HOH F 3 .   ? -4.125  52.402  26.700 1.00 46.73 ?  615  HOH B O    1 
HETATM 12719 O O    . HOH F 3 .   ? -3.872  27.622  73.716 1.00 20.31 ?  616  HOH B O    1 
HETATM 12720 O O    . HOH F 3 .   ? 10.859  51.406  52.051 1.00 24.97 ?  617  HOH B O    1 
HETATM 12721 O O    . HOH F 3 .   ? -0.438  57.226  43.548 1.00 18.06 ?  618  HOH B O    1 
HETATM 12722 O O    . HOH F 3 .   ? 10.984  25.170  28.739 1.00 31.24 ?  619  HOH B O    1 
HETATM 12723 O O    . HOH F 3 .   ? -3.305  41.119  26.452 1.00 36.60 ?  620  HOH B O    1 
HETATM 12724 O O    . HOH F 3 .   ? 4.692   47.919  27.478 1.00 20.40 ?  621  HOH B O    1 
HETATM 12725 O O    . HOH F 3 .   ? -9.293  57.073  57.390 1.00 28.79 ?  622  HOH B O    1 
HETATM 12726 O O    . HOH F 3 .   ? -23.300 42.579  50.149 1.00 21.12 ?  623  HOH B O    1 
HETATM 12727 O O    . HOH F 3 .   ? -24.321 48.568  57.729 1.00 36.76 ?  624  HOH B O    1 
HETATM 12728 O O    . HOH F 3 .   ? -9.075  57.223  53.137 1.00 24.64 ?  625  HOH B O    1 
HETATM 12729 O O    . HOH F 3 .   ? -4.447  29.201  59.028 1.00 14.64 ?  626  HOH B O    1 
HETATM 12730 O O    . HOH F 3 .   ? -19.300 20.194  60.975 1.00 41.39 ?  627  HOH B O    1 
HETATM 12731 O O    . HOH F 3 .   ? -21.673 22.046  41.477 1.00 38.82 ?  628  HOH B O    1 
HETATM 12732 O O    . HOH F 3 .   ? -10.330 31.297  79.745 1.00 31.36 ?  629  HOH B O    1 
HETATM 12733 O O    . HOH F 3 .   ? -8.686  40.067  61.539 1.00 24.80 ?  630  HOH B O    1 
HETATM 12734 O O    . HOH F 3 .   ? 11.588  34.345  26.766 1.00 24.20 ?  631  HOH B O    1 
HETATM 12735 O O    . HOH F 3 .   ? -17.324 41.616  23.981 1.00 33.94 ?  632  HOH B O    1 
HETATM 12736 O O    . HOH F 3 .   ? 0.954   32.012  64.122 1.00 14.82 ?  633  HOH B O    1 
HETATM 12737 O O    . HOH F 3 .   ? -5.858  32.821  69.531 1.00 23.99 ?  634  HOH B O    1 
HETATM 12738 O O    . HOH F 3 .   ? -11.524 20.262  56.825 1.00 32.99 ?  635  HOH B O    1 
HETATM 12739 O O    . HOH F 3 .   ? 18.264  43.329  42.652 1.00 24.10 ?  636  HOH B O    1 
HETATM 12740 O O    . HOH F 3 .   ? -28.449 34.423  60.362 1.00 20.33 ?  637  HOH B O    1 
HETATM 12741 O O    . HOH F 3 .   ? -27.792 16.232  37.098 1.00 22.53 ?  638  HOH B O    1 
HETATM 12742 O O    . HOH F 3 .   ? -16.050 31.888  40.369 1.00 14.77 ?  639  HOH B O    1 
HETATM 12743 O O    . HOH F 3 .   ? -5.916  20.391  53.267 1.00 30.29 ?  640  HOH B O    1 
HETATM 12744 O O    . HOH F 3 .   ? -33.956 29.906  48.675 1.00 25.00 ?  641  HOH B O    1 
HETATM 12745 O O    . HOH F 3 .   ? -10.812 28.658  52.102 1.00 15.18 ?  642  HOH B O    1 
HETATM 12746 O O    . HOH F 3 .   ? -10.276 57.268  47.775 1.00 27.20 ?  643  HOH B O    1 
HETATM 12747 O O    . HOH F 3 .   ? 2.009   59.946  46.510 1.00 32.57 ?  644  HOH B O    1 
HETATM 12748 O O    . HOH F 3 .   ? 17.178  43.521  49.052 1.00 24.01 ?  645  HOH B O    1 
HETATM 12749 O O    . HOH F 3 .   ? -28.674 45.612  57.301 1.00 28.84 ?  646  HOH B O    1 
HETATM 12750 O O    . HOH F 3 .   ? -18.873 25.471  43.586 1.00 27.54 ?  647  HOH B O    1 
HETATM 12751 O O    . HOH F 3 .   ? 16.748  32.494  50.013 1.00 23.60 ?  648  HOH B O    1 
HETATM 12752 O O    . HOH F 3 .   ? -30.815 38.140  50.508 1.00 39.67 ?  649  HOH B O    1 
HETATM 12753 O O    . HOH F 3 .   ? 5.214   24.693  38.114 1.00 19.99 ?  650  HOH B O    1 
HETATM 12754 O O    . HOH F 3 .   ? -22.767 34.150  38.630 1.00 23.78 ?  651  HOH B O    1 
HETATM 12755 O O    . HOH F 3 .   ? 2.332   55.853  54.625 1.00 37.68 ?  652  HOH B O    1 
HETATM 12756 O O    . HOH F 3 .   ? -8.426  20.734  54.370 1.00 30.84 ?  653  HOH B O    1 
HETATM 12757 O O    . HOH F 3 .   ? 1.713   35.027  48.064 1.00 12.83 ?  654  HOH B O    1 
HETATM 12758 O O    . HOH F 3 .   ? 11.297  24.077  32.000 1.00 26.00 ?  655  HOH B O    1 
HETATM 12759 O O    . HOH F 3 .   ? 6.278   37.892  20.437 1.00 37.24 ?  656  HOH B O    1 
HETATM 12760 O O    . HOH F 3 .   ? -0.756  29.072  42.697 1.00 12.69 ?  657  HOH B O    1 
HETATM 12761 O O    . HOH F 3 .   ? 4.317   27.630  65.032 1.00 20.13 ?  658  HOH B O    1 
HETATM 12762 O O    . HOH F 3 .   ? -28.647 33.647  54.782 1.00 21.28 ?  659  HOH B O    1 
HETATM 12763 O O    . HOH F 3 .   ? 12.605  48.922  32.246 1.00 24.52 ?  660  HOH B O    1 
HETATM 12764 O O    . HOH F 3 .   ? -0.661  59.261  53.669 1.00 29.74 ?  661  HOH B O    1 
HETATM 12765 O O    . HOH F 3 .   ? -8.347  37.448  26.179 1.00 38.86 ?  662  HOH B O    1 
HETATM 12766 O O    . HOH F 3 .   ? 5.424   29.091  63.034 1.00 16.80 ?  663  HOH B O    1 
HETATM 12767 O O    . HOH F 3 .   ? -23.137 33.634  34.831 1.00 31.20 ?  664  HOH B O    1 
HETATM 12768 O O    . HOH F 3 .   ? -0.271  39.706  30.013 1.00 14.70 ?  665  HOH B O    1 
HETATM 12769 O O    . HOH F 3 .   ? -25.129 45.897  47.464 1.00 32.88 ?  666  HOH B O    1 
HETATM 12770 O O    . HOH F 3 .   ? -2.674  24.793  52.158 1.00 27.34 ?  667  HOH B O    1 
HETATM 12771 O O    . HOH F 3 .   ? 12.193  25.792  50.904 1.00 23.73 ?  668  HOH B O    1 
HETATM 12772 O O    . HOH F 3 .   ? 3.881   49.303  56.488 1.00 24.30 ?  669  HOH B O    1 
HETATM 12773 O O    . HOH F 3 .   ? 10.560  33.724  58.238 1.00 24.40 ?  670  HOH B O    1 
HETATM 12774 O O    . HOH F 3 .   ? -4.585  24.744  70.715 1.00 25.07 ?  671  HOH B O    1 
HETATM 12775 O O    . HOH F 3 .   ? 1.407   31.291  66.799 1.00 25.75 ?  672  HOH B O    1 
HETATM 12776 O O    . HOH F 3 .   ? -24.260 43.419  74.412 1.00 34.74 ?  673  HOH B O    1 
HETATM 12777 O O    . HOH F 3 .   ? -26.830 45.946  42.852 1.00 22.47 ?  674  HOH B O    1 
HETATM 12778 O O    . HOH F 3 .   ? 6.516   50.117  58.786 1.00 42.45 ?  675  HOH B O    1 
HETATM 12779 O O    . HOH F 3 .   ? -18.112 14.404  28.726 1.00 12.65 ?  676  HOH B O    1 
HETATM 12780 O O    . HOH F 3 .   ? 8.285   43.153  58.107 1.00 23.29 ?  677  HOH B O    1 
HETATM 12781 O O    . HOH F 3 .   ? 3.278   49.706  53.651 1.00 17.40 ?  678  HOH B O    1 
HETATM 12782 O O    . HOH F 3 .   ? 5.221   23.115  34.502 1.00 18.89 ?  679  HOH B O    1 
HETATM 12783 O O    . HOH F 3 .   ? -3.630  60.684  37.637 1.00 37.54 ?  680  HOH B O    1 
HETATM 12784 O O    . HOH F 3 .   ? 9.553   24.932  61.168 1.00 16.34 ?  681  HOH B O    1 
HETATM 12785 O O    . HOH F 3 .   ? -25.979 47.569  32.569 1.00 25.64 ?  682  HOH B O    1 
HETATM 12786 O O    . HOH F 3 .   ? -19.508 25.823  37.178 1.00 30.20 ?  683  HOH B O    1 
HETATM 12787 O O    . HOH F 3 .   ? 20.095  40.796  40.765 1.00 23.06 ?  684  HOH B O    1 
HETATM 12788 O O    . HOH F 3 .   ? -24.162 49.978  31.221 1.00 48.22 ?  685  HOH B O    1 
HETATM 12789 O O    . HOH F 3 .   ? -6.945  44.504  37.613 1.00 13.02 ?  686  HOH B O    1 
HETATM 12790 O O    . HOH F 3 .   ? -3.620  32.296  55.299 1.00 13.53 ?  687  HOH B O    1 
HETATM 12791 O O    . HOH F 3 .   ? -1.851  50.369  24.127 1.00 41.57 ?  688  HOH B O    1 
HETATM 12792 O O    . HOH F 3 .   ? -30.698 36.480  71.286 1.00 44.42 ?  689  HOH B O    1 
HETATM 12793 O O    . HOH F 3 .   ? 27.326  28.480  42.835 1.00 23.91 ?  690  HOH B O    1 
HETATM 12794 O O    . HOH F 3 .   ? -16.204 53.736  33.062 1.00 25.09 ?  691  HOH B O    1 
HETATM 12795 O O    . HOH F 3 .   ? -0.295  38.159  23.749 1.00 37.68 ?  692  HOH B O    1 
HETATM 12796 O O    . HOH F 3 .   ? 6.206   23.347  29.729 1.00 26.25 ?  693  HOH B O    1 
HETATM 12797 O O    . HOH F 3 .   ? -29.100 45.546  61.006 1.00 30.59 ?  694  HOH B O    1 
HETATM 12798 O O    . HOH F 3 .   ? -5.050  56.826  48.649 1.00 21.39 ?  695  HOH B O    1 
HETATM 12799 O O    . HOH F 3 .   ? -16.438 35.721  75.120 1.00 33.69 ?  696  HOH B O    1 
HETATM 12800 O O    . HOH F 3 .   ? -23.279 40.226  31.898 1.00 31.06 ?  697  HOH B O    1 
HETATM 12801 O O    . HOH F 3 .   ? 10.647  50.864  56.259 1.00 38.29 ?  698  HOH B O    1 
HETATM 12802 O O    . HOH F 3 .   ? -12.090 53.538  66.067 1.00 42.33 ?  699  HOH B O    1 
HETATM 12803 O O    . HOH F 3 .   ? -21.437 24.727  35.237 1.00 29.35 ?  700  HOH B O    1 
HETATM 12804 O O    . HOH F 3 .   ? 0.324   48.485  61.774 1.00 25.84 ?  701  HOH B O    1 
HETATM 12805 O O    . HOH F 3 .   ? 0.921   33.788  30.199 1.00 35.72 ?  702  HOH B O    1 
HETATM 12806 O O    . HOH F 3 .   ? -19.363 27.690  46.424 1.00 51.46 ?  703  HOH B O    1 
HETATM 12807 O O    . HOH F 3 .   ? -22.246 46.995  31.018 1.00 31.40 ?  704  HOH B O    1 
HETATM 12808 O O    . HOH F 3 .   ? 11.350  47.706  26.201 1.00 33.80 ?  705  HOH B O    1 
HETATM 12809 O O    . HOH F 3 .   ? 1.101   49.728  59.417 1.00 27.47 ?  706  HOH B O    1 
HETATM 12810 O O    . HOH F 3 .   ? -27.970 26.973  39.150 1.00 31.84 ?  707  HOH B O    1 
HETATM 12811 O O    . HOH F 3 .   ? -25.148 53.322  38.995 1.00 35.46 ?  708  HOH B O    1 
HETATM 12812 O O    . HOH F 3 .   ? 14.395  20.651  27.229 1.00 40.89 ?  709  HOH B O    1 
HETATM 12813 O O    . HOH F 3 .   ? -25.856 29.966  64.689 1.00 21.34 ?  710  HOH B O    1 
HETATM 12814 O O    . HOH F 3 .   ? -8.878  41.013  25.074 1.00 31.16 ?  711  HOH B O    1 
HETATM 12815 O O    . HOH F 3 .   ? 0.832   27.851  51.742 1.00 13.81 ?  712  HOH B O    1 
HETATM 12816 O O    . HOH F 3 .   ? -23.665 23.439  32.816 1.00 20.65 ?  713  HOH B O    1 
HETATM 12817 O O    . HOH F 3 .   ? -19.313 22.368  31.946 1.00 18.57 ?  714  HOH B O    1 
HETATM 12818 O O    . HOH F 3 .   ? -21.673 44.849  50.170 1.00 21.78 ?  715  HOH B O    1 
HETATM 12819 O O    . HOH F 3 .   ? 19.567  43.794  39.534 1.00 31.26 ?  716  HOH B O    1 
HETATM 12820 O O    . HOH F 3 .   ? -15.687 25.831  37.435 1.00 22.40 ?  717  HOH B O    1 
HETATM 12821 O O    . HOH F 3 .   ? -28.765 27.105  59.639 1.00 34.21 ?  718  HOH B O    1 
HETATM 12822 O O    . HOH F 3 .   ? 17.165  35.311  28.153 1.00 39.85 ?  719  HOH B O    1 
HETATM 12823 O O    . HOH F 3 .   ? 4.427   47.611  60.291 1.00 34.23 ?  720  HOH B O    1 
HETATM 12824 O O    . HOH F 3 .   ? -5.368  17.965  67.734 1.00 34.37 ?  721  HOH B O    1 
HETATM 12825 O O    . HOH F 3 .   ? -0.175  41.051  37.506 1.00 11.70 ?  722  HOH B O    1 
HETATM 12826 O O    . HOH F 3 .   ? -16.961 36.379  32.498 1.00 14.01 ?  723  HOH B O    1 
HETATM 12827 O O    . HOH F 3 .   ? -25.220 47.254  64.947 1.00 38.62 ?  724  HOH B O    1 
HETATM 12828 O O    . HOH F 3 .   ? -14.285 29.130  74.678 1.00 34.26 ?  725  HOH B O    1 
HETATM 12829 O O    . HOH F 3 .   ? -11.150 22.636  55.400 1.00 37.03 ?  726  HOH B O    1 
HETATM 12830 O O    . HOH F 3 .   ? -17.414 28.054  41.064 1.00 19.54 ?  727  HOH B O    1 
HETATM 12831 O O    . HOH F 3 .   ? -3.929  32.307  71.438 1.00 28.50 ?  728  HOH B O    1 
HETATM 12832 O O    . HOH F 3 .   ? 8.733   36.955  24.221 1.00 25.47 ?  729  HOH B O    1 
HETATM 12833 O O    . HOH F 3 .   ? -6.765  50.102  64.264 1.00 37.29 ?  730  HOH B O    1 
HETATM 12834 O O    . HOH F 3 .   ? -19.343 20.081  39.389 1.00 37.02 ?  731  HOH B O    1 
HETATM 12835 O O    . HOH F 3 .   ? -21.245 37.094  47.815 1.00 30.08 ?  732  HOH B O    1 
HETATM 12836 O O    . HOH F 3 .   ? 14.207  47.235  43.085 1.00 24.58 ?  733  HOH B O    1 
HETATM 12837 O O    . HOH F 3 .   ? -8.179  29.463  49.923 1.00 14.60 ?  734  HOH B O    1 
HETATM 12838 O O    . HOH F 3 .   ? 2.499   57.727  56.147 1.00 41.31 ?  735  HOH B O    1 
HETATM 12839 O O    . HOH F 3 .   ? -16.743 47.017  33.831 1.00 17.64 ?  736  HOH B O    1 
HETATM 12840 O O    . HOH F 3 .   ? -21.147 40.054  28.462 1.00 39.18 ?  737  HOH B O    1 
HETATM 12841 O O    . HOH F 3 .   ? 20.202  43.698  36.312 1.00 26.79 ?  738  HOH B O    1 
HETATM 12842 O O    . HOH F 3 .   ? -4.065  58.513  60.895 1.00 30.58 ?  739  HOH B O    1 
HETATM 12843 O O    . HOH F 3 .   ? -0.937  19.545  64.136 1.00 25.26 ?  740  HOH B O    1 
HETATM 12844 O O    . HOH F 3 .   ? -11.679 30.480  35.263 1.00 27.47 ?  741  HOH B O    1 
HETATM 12845 O O    . HOH F 3 .   ? 5.144   37.045  66.565 1.00 24.12 ?  742  HOH B O    1 
HETATM 12846 O O    . HOH F 3 .   ? -2.558  39.185  69.772 1.00 39.61 ?  743  HOH B O    1 
HETATM 12847 O O    . HOH F 3 .   ? -20.152 33.608  73.219 1.00 25.39 ?  744  HOH B O    1 
HETATM 12848 O O    . HOH F 3 .   ? -25.638 39.970  36.175 1.00 24.70 ?  745  HOH B O    1 
HETATM 12849 O O    . HOH F 3 .   ? -21.865 25.571  62.183 1.00 19.84 ?  746  HOH B O    1 
HETATM 12850 O O    . HOH F 3 .   ? -22.735 24.718  42.969 1.00 37.59 ?  747  HOH B O    1 
HETATM 12851 O O    . HOH F 3 .   ? -28.193 30.915  69.132 1.00 34.05 ?  748  HOH B O    1 
HETATM 12852 O O    . HOH F 3 .   ? -21.492 60.765  41.345 1.00 27.86 ?  749  HOH B O    1 
HETATM 12853 O O    . HOH F 3 .   ? -21.200 54.239  37.327 1.00 17.60 ?  750  HOH B O    1 
HETATM 12854 O O    . HOH F 3 .   ? 2.146   34.517  63.997 1.00 15.58 ?  751  HOH B O    1 
HETATM 12855 O O    . HOH F 3 .   ? -4.779  42.481  26.242 1.00 30.11 ?  752  HOH B O    1 
HETATM 12856 O O    . HOH F 3 .   ? 7.362   22.968  53.804 1.00 23.22 ?  753  HOH B O    1 
HETATM 12857 O O    . HOH F 3 .   ? -9.026  36.818  75.822 1.00 36.36 ?  754  HOH B O    1 
HETATM 12858 O O    . HOH F 3 .   ? 13.076  33.017  25.264 1.00 32.28 ?  755  HOH B O    1 
HETATM 12859 O O    . HOH F 3 .   ? -29.171 38.756  48.208 1.00 24.50 ?  756  HOH B O    1 
HETATM 12860 O O    . HOH F 3 .   ? -1.778  36.580  68.584 1.00 29.07 ?  757  HOH B O    1 
HETATM 12861 O O    . HOH F 3 .   ? -26.073 36.317  40.371 1.00 33.38 ?  758  HOH B O    1 
HETATM 12862 O O    . HOH F 3 .   ? 2.377   19.535  53.098 1.00 24.29 ?  759  HOH B O    1 
HETATM 12863 O O    . HOH F 3 .   ? 22.925  30.342  46.772 1.00 23.75 ?  760  HOH B O    1 
HETATM 12864 O O    . HOH F 3 .   ? -7.632  33.428  75.095 1.00 29.17 ?  761  HOH B O    1 
HETATM 12865 O O    . HOH F 3 .   ? 13.836  23.749  24.189 1.00 35.71 ?  762  HOH B O    1 
HETATM 12866 O O    . HOH F 3 .   ? 7.261   27.592  61.345 1.00 26.81 ?  763  HOH B O    1 
HETATM 12867 O O    . HOH F 3 .   ? -1.240  32.924  31.343 1.00 27.83 ?  764  HOH B O    1 
HETATM 12868 O O    . HOH F 3 .   ? 6.127   50.142  33.250 1.00 17.94 ?  765  HOH B O    1 
HETATM 12869 O O    . HOH F 3 .   ? -33.203 23.983  55.261 1.00 33.51 ?  766  HOH B O    1 
HETATM 12870 O O    . HOH F 3 .   ? -18.211 50.999  63.927 1.00 23.63 ?  767  HOH B O    1 
HETATM 12871 O O    . HOH F 3 .   ? -17.200 42.504  77.745 1.00 36.05 ?  768  HOH B O    1 
HETATM 12872 O O    . HOH F 3 .   ? 18.689  45.338  33.700 1.00 23.99 ?  769  HOH B O    1 
HETATM 12873 O O    . HOH F 3 .   ? -14.784 28.554  46.927 1.00 20.98 ?  770  HOH B O    1 
HETATM 12874 O O    . HOH F 3 .   ? -18.457 23.580  58.621 1.00 31.36 ?  771  HOH B O    1 
HETATM 12875 O O    . HOH F 3 .   ? -25.598 14.754  40.788 1.00 27.17 ?  772  HOH B O    1 
HETATM 12876 O O    . HOH F 3 .   ? -1.488  41.909  69.757 1.00 35.88 ?  773  HOH B O    1 
HETATM 12877 O O    . HOH F 3 .   ? 5.470   47.245  49.728 1.00 19.93 ?  774  HOH B O    1 
HETATM 12878 O O    . HOH F 3 .   ? 14.795  49.402  47.505 1.00 30.26 ?  775  HOH B O    1 
HETATM 12879 O O    . HOH F 3 .   ? -6.634  40.853  26.494 1.00 31.07 ?  776  HOH B O    1 
HETATM 12880 O O    . HOH F 3 .   ? -19.088 17.935  63.394 1.00 31.16 ?  777  HOH B O    1 
HETATM 12881 O O    . HOH F 3 .   ? -10.015 27.473  80.419 1.00 42.21 ?  778  HOH B O    1 
HETATM 12882 O O    . HOH F 3 .   ? -25.468 25.376  34.325 1.00 32.66 ?  779  HOH B O    1 
HETATM 12883 O O    . HOH F 3 .   ? -18.608 60.069  43.129 1.00 35.36 ?  780  HOH B O    1 
HETATM 12884 O O    . HOH F 3 .   ? 15.365  49.599  43.888 1.00 36.74 ?  781  HOH B O    1 
HETATM 12885 O O    . HOH F 3 .   ? -24.498 44.568  48.739 1.00 32.45 ?  782  HOH B O    1 
HETATM 12886 O O    . HOH F 3 .   ? 6.928   54.768  53.901 1.00 39.03 ?  783  HOH B O    1 
HETATM 12887 O O    . HOH F 3 .   ? -8.286  33.869  70.655 1.00 24.10 ?  784  HOH B O    1 
HETATM 12888 O O    . HOH F 3 .   ? 1.520   48.634  32.552 1.00 17.64 ?  785  HOH B O    1 
HETATM 12889 O O    . HOH F 3 .   ? -11.365 21.966  72.801 1.00 21.14 ?  786  HOH B O    1 
HETATM 12890 O O    . HOH F 3 .   ? 12.589  27.948  26.581 1.00 20.41 ?  787  HOH B O    1 
HETATM 12891 O O    . HOH F 3 .   ? -15.509 19.058  70.502 1.00 24.60 ?  788  HOH B O    1 
HETATM 12892 O O    . HOH F 3 .   ? -21.499 53.225  63.925 1.00 40.55 ?  789  HOH B O    1 
HETATM 12893 O O    . HOH F 3 .   ? 19.615  35.619  31.583 1.00 34.69 ?  790  HOH B O    1 
HETATM 12894 O O    . HOH F 3 .   ? -12.770 48.513  67.047 1.00 28.07 ?  791  HOH B O    1 
HETATM 12895 O O    . HOH F 3 .   ? -30.388 42.545  63.651 1.00 33.75 ?  792  HOH B O    1 
HETATM 12896 O O    . HOH F 3 .   ? -10.942 32.071  41.869 1.00 17.25 ?  793  HOH B O    1 
HETATM 12897 O O    . HOH F 3 .   ? -19.436 45.814  54.761 1.00 18.13 ?  794  HOH B O    1 
HETATM 12898 O O    . HOH F 3 .   ? -8.449  19.023  63.464 1.00 23.47 ?  795  HOH B O    1 
HETATM 12899 O O    . HOH F 3 .   ? -1.357  51.832  29.884 1.00 38.45 ?  796  HOH B O    1 
HETATM 12900 O O    . HOH F 3 .   ? -15.441 38.545  74.151 1.00 28.47 ?  797  HOH B O    1 
HETATM 12901 O O    . HOH F 3 .   ? -8.684  35.476  28.130 1.00 27.65 ?  798  HOH B O    1 
HETATM 12902 O O    . HOH F 3 .   ? -23.424 54.988  46.983 1.00 31.47 ?  799  HOH B O    1 
HETATM 12903 O O    . HOH F 3 .   ? -22.318 28.877  37.092 1.00 34.25 ?  800  HOH B O    1 
HETATM 12904 O O    . HOH F 3 .   ? -6.511  58.299  43.419 1.00 17.62 ?  801  HOH B O    1 
HETATM 12905 O O    . HOH F 3 .   ? -14.492 30.100  38.839 1.00 19.72 ?  802  HOH B O    1 
HETATM 12906 O O    . HOH F 3 .   ? 9.100   40.240  63.067 1.00 37.44 ?  803  HOH B O    1 
HETATM 12907 O O    . HOH F 3 .   ? -2.767  30.093  56.881 1.00 14.87 ?  804  HOH B O    1 
HETATM 12908 O O    . HOH F 3 .   ? -7.459  17.394  60.937 1.00 25.34 ?  805  HOH B O    1 
HETATM 12909 O O    . HOH F 3 .   ? -30.218 20.341  53.521 1.00 41.59 ?  806  HOH B O    1 
HETATM 12910 O O    . HOH F 3 .   ? -15.865 36.466  27.323 1.00 26.28 ?  807  HOH B O    1 
HETATM 12911 O O    . HOH F 3 .   ? -3.276  57.783  43.844 1.00 15.81 ?  808  HOH B O    1 
HETATM 12912 O O    . HOH F 3 .   ? -0.670  26.963  36.263 1.00 14.97 ?  809  HOH B O    1 
HETATM 12913 O O    . HOH F 3 .   ? -21.027 46.069  52.483 1.00 25.96 ?  810  HOH B O    1 
HETATM 12914 O O    . HOH F 3 .   ? 20.415  36.237  38.897 1.00 25.90 ?  811  HOH B O    1 
HETATM 12915 O O    . HOH F 3 .   ? -28.027 46.312  35.317 1.00 22.56 ?  812  HOH B O    1 
HETATM 12916 O O    . HOH F 3 .   ? -27.315 54.299  40.664 1.00 45.87 ?  813  HOH B O    1 
HETATM 12917 O O    . HOH F 3 .   ? -19.266 23.663  36.252 1.00 32.03 ?  814  HOH B O    1 
HETATM 12918 O O    . HOH F 3 .   ? -23.614 44.980  53.758 1.00 32.60 ?  815  HOH B O    1 
HETATM 12919 O O    . HOH F 3 .   ? 4.960   25.543  40.515 1.00 21.20 ?  816  HOH B O    1 
HETATM 12920 O O    . HOH F 3 .   ? 9.488   46.692  18.671 1.00 36.92 ?  817  HOH B O    1 
HETATM 12921 O O    . HOH F 3 .   ? 9.103   24.487  34.134 1.00 24.45 ?  818  HOH B O    1 
HETATM 12922 O O    . HOH F 3 .   ? -17.138 48.232  56.989 1.00 18.32 ?  819  HOH B O    1 
HETATM 12923 O O    . HOH F 3 .   ? 8.775   24.681  36.167 1.00 35.15 ?  820  HOH B O    1 
HETATM 12924 O O    . HOH F 3 .   ? 0.758   53.880  55.076 1.00 21.69 ?  821  HOH B O    1 
HETATM 12925 O O    . HOH F 3 .   ? -0.719  17.545  55.324 1.00 24.58 ?  822  HOH B O    1 
HETATM 12926 O O    . HOH F 3 .   ? -19.916 37.694  29.347 1.00 35.65 ?  823  HOH B O    1 
HETATM 12927 O O    . HOH F 3 .   ? 3.692   57.915  34.168 1.00 45.63 ?  824  HOH B O    1 
HETATM 12928 O O    . HOH F 3 .   ? 1.239   36.594  29.564 1.00 23.82 ?  825  HOH B O    1 
HETATM 12929 O O    . HOH F 3 .   ? 20.584  24.354  42.748 1.00 24.81 ?  826  HOH B O    1 
HETATM 12930 O O    . HOH F 3 .   ? -14.757 17.937  62.099 1.00 37.73 ?  827  HOH B O    1 
HETATM 12931 O O    . HOH F 3 .   ? -31.004 39.269  57.901 1.00 32.77 ?  828  HOH B O    1 
HETATM 12932 O O    . HOH F 3 .   ? -29.589 34.034  66.751 1.00 25.65 ?  829  HOH B O    1 
HETATM 12933 O O    . HOH F 3 .   ? 3.856   56.534  43.154 1.00 31.64 ?  830  HOH B O    1 
HETATM 12934 O O    . HOH F 3 .   ? 13.847  32.582  59.684 1.00 32.38 ?  831  HOH B O    1 
HETATM 12935 O O    . HOH F 3 .   ? -1.667  25.364  66.997 1.00 22.10 ?  832  HOH B O    1 
HETATM 12936 O O    . HOH F 3 .   ? -25.134 42.037  77.420 1.00 39.20 ?  833  HOH B O    1 
HETATM 12937 O O    . HOH F 3 .   ? -0.028  27.523  68.197 1.00 22.24 ?  834  HOH B O    1 
HETATM 12938 O O    . HOH F 3 .   ? -27.629 24.544  50.153 1.00 32.55 ?  835  HOH B O    1 
HETATM 12939 O O    . HOH F 3 .   ? -11.878 43.378  71.425 1.00 25.94 ?  836  HOH B O    1 
HETATM 12940 O O    . HOH F 3 .   ? -3.239  33.518  31.366 1.00 27.06 ?  837  HOH B O    1 
HETATM 12941 O O    . HOH F 3 .   ? -29.210 23.087  48.077 1.00 32.16 ?  838  HOH B O    1 
HETATM 12942 O O    . HOH F 3 .   ? -28.517 47.856  41.814 1.00 26.41 ?  839  HOH B O    1 
HETATM 12943 O O    . HOH F 3 .   ? -29.402 32.814  58.232 1.00 23.45 ?  840  HOH B O    1 
HETATM 12944 O O    . HOH F 3 .   ? -20.107 37.669  45.418 1.00 28.96 ?  841  HOH B O    1 
HETATM 12945 O O    . HOH F 3 .   ? -5.611  61.021  52.851 1.00 40.55 ?  842  HOH B O    1 
HETATM 12946 O O    . HOH F 3 .   ? -35.815 34.103  50.605 1.00 31.40 ?  843  HOH B O    1 
HETATM 12947 O O    . HOH F 3 .   ? 6.134   37.130  23.665 1.00 36.31 ?  844  HOH B O    1 
HETATM 12948 O O    . HOH F 3 .   ? 18.002  45.180  44.439 1.00 37.90 ?  845  HOH B O    1 
HETATM 12949 O O    . HOH F 3 .   ? -22.871 52.353  47.533 1.00 22.65 ?  846  HOH B O    1 
HETATM 12950 O O    . HOH F 3 .   ? -15.667 28.912  76.302 1.00 45.65 ?  847  HOH B O    1 
HETATM 12951 O O    . HOH F 3 .   ? 9.436   47.257  55.650 1.00 30.81 ?  848  HOH B O    1 
HETATM 12952 O O    . HOH F 3 .   ? -26.208 30.067  72.390 1.00 33.98 ?  849  HOH B O    1 
HETATM 12953 O O    . HOH F 3 .   ? -20.796 23.770  59.863 1.00 42.82 ?  850  HOH B O    1 
HETATM 12954 O O    . HOH F 3 .   ? -12.861 40.979  22.701 1.00 44.68 ?  851  HOH B O    1 
HETATM 12955 O O    . HOH F 3 .   ? 11.291  49.071  53.535 1.00 35.29 ?  852  HOH B O    1 
HETATM 12956 O O    . HOH F 3 .   ? -25.784 43.218  48.725 1.00 32.10 ?  853  HOH B O    1 
HETATM 12957 O O    . HOH F 3 .   ? -25.415 23.247  51.279 1.00 44.14 ?  854  HOH B O    1 
HETATM 12958 O O    . HOH F 3 .   ? -10.658 35.578  27.512 1.00 27.28 ?  855  HOH B O    1 
HETATM 12959 O O    . HOH F 3 .   ? -12.381 44.019  23.711 1.00 29.00 ?  856  HOH B O    1 
HETATM 12960 O O    . HOH F 3 .   ? -26.368 27.384  38.081 1.00 49.78 ?  857  HOH B O    1 
HETATM 12961 O O    . HOH F 3 .   ? -22.752 52.070  36.581 1.00 23.77 ?  858  HOH B O    1 
HETATM 12962 O O    . HOH F 3 .   ? 19.898  34.241  25.910 1.00 32.92 ?  859  HOH B O    1 
HETATM 12963 O O    . HOH F 3 .   ? -21.056 17.643  37.564 1.00 28.00 ?  860  HOH B O    1 
HETATM 12964 O O    . HOH F 3 .   ? -7.187  25.849  49.861 1.00 43.51 ?  861  HOH B O    1 
HETATM 12965 O O    . HOH F 3 .   ? -8.547  17.984  71.160 1.00 39.95 ?  862  HOH B O    1 
HETATM 12966 O O    . HOH F 3 .   ? 10.342  26.305  26.422 1.00 28.65 ?  863  HOH B O    1 
HETATM 12967 O O    . HOH F 3 .   ? -3.259  22.238  51.364 1.00 35.45 ?  864  HOH B O    1 
HETATM 12968 O O    . HOH F 3 .   ? 24.242  34.058  43.852 1.00 35.28 ?  865  HOH B O    1 
HETATM 12969 O O    . HOH F 3 .   ? -4.133  19.837  71.432 1.00 25.03 ?  866  HOH B O    1 
HETATM 12970 O O    . HOH F 3 .   ? -11.472 58.352  50.984 1.00 47.00 ?  867  HOH B O    1 
HETATM 12971 O O    . HOH F 3 .   ? -5.924  52.094  25.434 1.00 38.21 ?  868  HOH B O    1 
HETATM 12972 O O    . HOH F 3 .   ? 15.869  35.885  24.855 1.00 44.29 ?  869  HOH B O    1 
HETATM 12973 O O    . HOH F 3 .   ? 17.688  33.342  24.527 1.00 34.53 ?  870  HOH B O    1 
HETATM 12974 O O    . HOH F 3 .   ? -14.045 29.185  35.877 1.00 29.47 ?  871  HOH B O    1 
HETATM 12975 O O    . HOH F 3 .   ? 8.343   58.604  48.157 1.00 37.16 ?  872  HOH B O    1 
HETATM 12976 O O    . HOH F 3 .   ? -9.416  22.462  52.561 1.00 42.10 ?  873  HOH B O    1 
HETATM 12977 O O    . HOH F 3 .   ? -19.567 54.351  51.845 1.00 38.43 ?  874  HOH B O    1 
HETATM 12978 O O    . HOH F 3 .   ? -0.565  30.352  29.207 1.00 32.32 ?  875  HOH B O    1 
HETATM 12979 O O    . HOH F 3 .   ? -14.266 31.645  79.310 1.00 36.85 ?  876  HOH B O    1 
HETATM 12980 O O    . HOH F 3 .   ? -4.614  35.349  27.870 1.00 41.52 ?  877  HOH B O    1 
HETATM 12981 O O    . HOH F 3 .   ? -23.247 31.504  38.074 1.00 33.25 ?  878  HOH B O    1 
HETATM 12982 O O    . HOH F 3 .   ? -14.678 44.047  22.235 1.00 36.23 ?  879  HOH B O    1 
HETATM 12983 O O    . HOH F 3 .   ? -28.183 30.187  67.204 1.00 44.28 ?  880  HOH B O    1 
HETATM 12984 O O    . HOH F 3 .   ? -11.422 46.455  22.759 1.00 30.02 ?  881  HOH B O    1 
HETATM 12985 O O    . HOH F 3 .   ? -2.115  22.112  34.601 1.00 26.54 ?  882  HOH B O    1 
HETATM 12986 O O    . HOH F 3 .   ? -11.649 54.387  31.804 1.00 26.11 ?  883  HOH B O    1 
HETATM 12987 O O    . HOH F 3 .   ? 16.987  49.238  34.545 1.00 31.24 ?  884  HOH B O    1 
HETATM 12988 O O    . HOH F 3 .   ? -30.274 19.794  62.185 1.00 41.21 ?  885  HOH B O    1 
HETATM 12989 O O    . HOH F 3 .   ? 20.987  19.847  33.309 1.00 41.59 ?  886  HOH B O    1 
HETATM 12990 O O    . HOH F 3 .   ? 15.779  45.675  50.249 1.00 28.81 ?  887  HOH B O    1 
HETATM 12991 O O    . HOH F 3 .   ? -12.325 26.685  80.056 1.00 35.13 ?  888  HOH B O    1 
HETATM 12992 O O    . HOH F 3 .   ? -28.897 49.888  43.550 1.00 47.65 ?  889  HOH B O    1 
HETATM 12993 O O    . HOH F 3 .   ? 16.288  50.345  45.868 1.00 43.88 ?  890  HOH B O    1 
HETATM 12994 O O    . HOH F 3 .   ? 3.811   24.384  59.693 1.00 16.73 ?  891  HOH B O    1 
HETATM 12995 O O    . HOH F 3 .   ? -21.280 60.449  44.958 1.00 43.03 ?  892  HOH B O    1 
HETATM 12996 O O    . HOH F 3 .   ? 10.995  24.817  56.991 1.00 30.84 ?  893  HOH B O    1 
HETATM 12997 O O    . HOH F 3 .   ? 2.009   42.869  22.134 1.00 32.12 ?  894  HOH B O    1 
HETATM 12998 O O    . HOH F 3 .   ? 8.832   47.116  25.691 1.00 37.94 ?  895  HOH B O    1 
HETATM 12999 O O    . HOH F 3 .   ? 20.912  37.079  34.951 1.00 46.43 ?  896  HOH B O    1 
HETATM 13000 O O    . HOH F 3 .   ? -5.622  34.078  29.830 1.00 30.66 ?  897  HOH B O    1 
HETATM 13001 O O    . HOH F 3 .   ? 13.541  51.738  48.629 1.00 31.72 ?  898  HOH B O    1 
HETATM 13002 O O    . HOH F 3 .   ? -3.181  30.932  31.303 1.00 38.39 ?  899  HOH B O    1 
HETATM 13003 O O    . HOH F 3 .   ? -26.165 46.676  45.291 1.00 28.32 ?  900  HOH B O    1 
HETATM 13004 O O    . HOH F 3 .   ? 9.539   44.658  56.162 1.00 39.43 ?  901  HOH B O    1 
HETATM 13005 O O    . HOH F 3 .   ? 10.492  50.755  32.757 1.00 33.43 ?  902  HOH B O    1 
HETATM 13006 O O    . HOH F 3 .   ? -23.832 24.353  63.495 1.00 41.12 ?  903  HOH B O    1 
HETATM 13007 O O    . HOH F 3 .   ? 9.371   56.957  46.343 1.00 30.55 ?  904  HOH B O    1 
HETATM 13008 O O    . HOH F 3 .   ? -3.744  28.933  49.131 1.00 18.88 ?  905  HOH B O    1 
HETATM 13009 O O    . HOH F 3 .   ? -9.270  31.175  46.596 1.00 17.67 ?  906  HOH B O    1 
HETATM 13010 O O    . HOH F 3 .   ? 1.502   18.214  63.722 1.00 26.13 ?  907  HOH B O    1 
HETATM 13011 O O    . HOH F 3 .   ? -34.934 25.513  62.277 1.00 36.08 ?  908  HOH B O    1 
HETATM 13012 O O    . HOH F 3 .   ? -16.839 39.167  24.433 1.00 38.51 ?  909  HOH B O    1 
HETATM 13013 O O    . HOH F 3 .   ? -18.210 25.541  40.170 1.00 32.15 ?  910  HOH B O    1 
HETATM 13014 O O    . HOH F 3 .   ? -25.646 27.984  40.621 1.00 30.14 ?  911  HOH B O    1 
HETATM 13015 O O    . HOH F 3 .   ? -35.805 31.662  54.148 1.00 46.18 ?  912  HOH B O    1 
HETATM 13016 O O    . HOH F 3 .   ? 3.796   44.471  60.744 1.00 26.25 ?  913  HOH B O    1 
HETATM 13017 O O    . HOH F 3 .   ? -9.429  30.100  37.707 1.00 22.54 ?  914  HOH B O    1 
HETATM 13018 O O    . HOH F 3 .   ? -2.750  59.121  35.988 1.00 39.84 ?  915  HOH B O    1 
HETATM 13019 O O    . HOH F 3 .   ? 0.873   21.670  64.975 1.00 23.60 ?  916  HOH B O    1 
HETATM 13020 O O    . HOH F 3 .   ? 12.134  43.755  56.659 1.00 44.92 ?  917  HOH B O    1 
HETATM 13021 O O    . HOH F 3 .   ? -12.575 28.727  44.692 1.00 37.09 ?  918  HOH B O    1 
HETATM 13022 O O    . HOH F 3 .   ? -12.782 38.774  77.211 1.00 41.13 ?  919  HOH B O    1 
HETATM 13023 O O    . HOH F 3 .   ? 6.273   31.030  26.586 1.00 29.90 ?  920  HOH B O    1 
HETATM 13024 O O    . HOH F 3 .   ? -18.073 52.121  32.178 1.00 26.47 ?  921  HOH B O    1 
HETATM 13025 O O    . HOH F 3 .   ? -13.918 51.037  66.197 1.00 40.08 ?  922  HOH B O    1 
HETATM 13026 O O    . HOH F 3 .   ? -24.887 54.008  35.302 1.00 42.29 ?  923  HOH B O    1 
HETATM 13027 O O    . HOH F 3 .   ? -32.773 42.680  40.089 1.00 38.85 ?  924  HOH B O    1 
HETATM 13028 O O    . HOH F 3 .   ? -28.339 43.733  34.619 1.00 31.85 ?  925  HOH B O    1 
HETATM 13029 O O    . HOH F 3 .   ? -4.397  34.554  33.693 1.00 21.21 ?  926  HOH B O    1 
HETATM 13030 O O    . HOH F 3 .   ? -11.262 18.283  61.856 1.00 50.51 ?  927  HOH B O    1 
HETATM 13031 O O    . HOH F 3 .   ? -17.299 52.580  51.471 1.00 20.96 ?  928  HOH B O    1 
HETATM 13032 O O    . HOH F 3 .   ? -10.584 42.262  22.788 1.00 39.50 ?  929  HOH B O    1 
HETATM 13033 O O    . HOH F 3 .   ? -32.961 37.437  58.655 1.00 38.71 ?  930  HOH B O    1 
HETATM 13034 O O    . HOH F 3 .   ? -0.262  45.545  68.591 1.00 37.38 ?  931  HOH B O    1 
HETATM 13035 O O    . HOH F 3 .   ? -7.773  52.571  64.839 1.00 36.76 ?  932  HOH B O    1 
HETATM 13036 O O    . HOH F 3 .   ? 13.217  32.708  56.518 1.00 32.50 ?  933  HOH B O    1 
HETATM 13037 O O    . HOH F 3 .   ? 0.136   24.736  52.101 1.00 20.06 ?  934  HOH B O    1 
HETATM 13038 O O    . HOH F 3 .   ? -26.231 41.356  74.494 1.00 40.90 ?  935  HOH B O    1 
HETATM 13039 O O    . HOH F 3 .   ? -0.228  35.885  27.509 1.00 25.28 ?  936  HOH B O    1 
HETATM 13040 O O    . HOH F 3 .   ? -29.341 41.414  47.357 1.00 35.85 ?  937  HOH B O    1 
HETATM 13041 O O    . HOH F 3 .   ? -26.069 46.470  50.096 1.00 45.54 ?  938  HOH B O    1 
HETATM 13042 O O    . HOH F 3 .   ? 2.533   51.793  27.742 1.00 38.11 ?  939  HOH B O    1 
HETATM 13043 O O    . HOH F 3 .   ? -20.109 38.825  49.709 1.00 21.10 ?  940  HOH B O    1 
HETATM 13044 O O    . HOH F 3 .   ? -9.389  25.070  50.215 1.00 39.20 ?  941  HOH B O    1 
HETATM 13045 O O    . HOH F 3 .   ? -18.777 52.839  57.185 1.00 34.91 ?  942  HOH B O    1 
HETATM 13046 O O    . HOH F 3 .   ? 7.354   37.134  68.254 1.00 25.45 ?  943  HOH B O    1 
HETATM 13047 O O    . HOH F 3 .   ? -24.249 57.760  39.500 1.00 40.15 ?  944  HOH B O    1 
HETATM 13048 O O    . HOH F 3 .   ? -6.274  29.141  47.887 1.00 17.26 ?  945  HOH B O    1 
HETATM 13049 O O    . HOH F 3 .   ? -22.620 50.615  57.744 1.00 41.61 ?  946  HOH B O    1 
HETATM 13050 O O    . HOH F 3 .   ? 20.871  18.296  31.186 1.00 28.39 ?  947  HOH B O    1 
HETATM 13051 O O    . HOH F 3 .   ? 14.471  24.336  50.137 1.00 34.29 ?  948  HOH B O    1 
HETATM 13052 O O    . HOH F 3 .   ? -4.924  25.234  48.766 1.00 44.59 ?  949  HOH B O    1 
HETATM 13053 O O    . HOH F 3 .   ? -18.303 50.509  55.732 1.00 29.95 ?  950  HOH B O    1 
HETATM 13054 O O    . HOH F 3 .   ? -1.929  14.652  58.133 1.00 43.71 ?  951  HOH B O    1 
HETATM 13055 O O    . HOH F 3 .   ? -26.434 49.464  46.322 1.00 38.11 ?  952  HOH B O    1 
HETATM 13056 O O    . HOH F 3 .   ? 3.827   37.373  26.530 1.00 23.79 ?  953  HOH B O    1 
HETATM 13057 O O    . HOH F 3 .   ? 15.358  30.711  59.348 1.00 35.76 ?  954  HOH B O    1 
HETATM 13058 O O    . HOH F 3 .   ? 12.586  35.710  58.437 1.00 38.48 ?  955  HOH B O    1 
HETATM 13059 O O    . HOH F 3 .   ? -10.758 58.606  53.410 1.00 47.52 ?  956  HOH B O    1 
HETATM 13060 O O    . HOH F 3 .   ? -6.268  47.357  23.487 1.00 38.94 ?  957  HOH B O    1 
HETATM 13061 O O    . HOH F 3 .   ? -34.841 24.706  53.720 1.00 41.51 ?  958  HOH B O    1 
HETATM 13062 O O    . HOH F 3 .   ? 21.260  38.702  39.746 1.00 31.51 ?  959  HOH B O    1 
HETATM 13063 O O    . HOH F 3 .   ? -13.608 38.361  22.796 1.00 41.19 ?  960  HOH B O    1 
HETATM 13064 O O    . HOH F 3 .   ? 23.911  34.459  41.560 1.00 37.46 ?  961  HOH B O    1 
HETATM 13065 O O    . HOH F 3 .   ? 22.110  31.133  38.706 1.00 26.28 ?  962  HOH B O    1 
HETATM 13066 O O    . HOH F 3 .   ? -31.815 38.487  71.917 1.00 47.58 ?  963  HOH B O    1 
HETATM 13067 O O    . HOH F 3 .   ? -0.788  51.562  33.116 1.00 30.54 ?  964  HOH B O    1 
HETATM 13068 O O    . HOH F 3 .   ? -7.689  17.892  66.117 1.00 35.36 ?  965  HOH B O    1 
HETATM 13069 O O    . HOH F 3 .   ? 11.310  23.323  54.627 1.00 40.80 ?  966  HOH B O    1 
HETATM 13070 O O    . HOH F 3 .   ? -14.353 55.336  31.815 1.00 28.74 ?  967  HOH B O    1 
HETATM 13071 O O    . HOH F 3 .   ? 10.797  23.259  59.399 1.00 20.71 ?  968  HOH B O    1 
HETATM 13072 O O    . HOH F 3 .   ? -2.606  29.721  44.593 1.00 13.43 ?  969  HOH B O    1 
HETATM 13073 O O    . HOH F 3 .   ? -20.658 43.130  27.236 1.00 38.20 ?  970  HOH B O    1 
HETATM 13074 O O    . HOH F 3 .   ? 19.078  33.499  33.317 1.00 27.19 ?  971  HOH B O    1 
HETATM 13075 O O    . HOH F 3 .   ? -6.178  53.439  66.747 1.00 41.97 ?  972  HOH B O    1 
HETATM 13076 O O    . HOH F 3 .   ? 8.667   44.789  60.211 1.00 39.91 ?  973  HOH B O    1 
HETATM 13077 O O    . HOH F 3 .   ? 2.678   33.624  27.970 1.00 25.41 ?  974  HOH B O    1 
HETATM 13078 O O    . HOH F 3 .   ? -5.882  33.248  71.838 1.00 39.51 ?  975  HOH B O    1 
HETATM 13079 O O    . HOH F 3 .   ? -10.470 27.590  49.640 1.00 26.49 ?  976  HOH B O    1 
HETATM 13080 O O    . HOH F 3 .   ? -31.183 33.079  46.779 1.00 34.22 ?  977  HOH B O    1 
HETATM 13081 O O    . HOH F 3 .   ? 3.749   50.061  31.855 1.00 18.89 ?  978  HOH B O    1 
HETATM 13082 O O    . HOH F 3 .   ? -14.571 25.788  39.794 1.00 45.19 ?  979  HOH B O    1 
HETATM 13083 O O    . HOH F 3 .   ? 16.773  39.097  24.168 1.00 42.05 ?  980  HOH B O    1 
HETATM 13084 O O    . HOH F 3 .   ? 13.986  26.093  60.360 1.00 27.13 ?  981  HOH B O    1 
HETATM 13085 O O    . HOH F 3 .   ? -25.030 30.474  39.949 1.00 35.24 ?  982  HOH B O    1 
HETATM 13086 O O    . HOH F 3 .   ? 18.984  48.215  33.121 1.00 45.62 ?  983  HOH B O    1 
HETATM 13087 O O    . HOH F 3 .   ? -18.825 50.956  53.169 1.00 37.53 ?  984  HOH B O    1 
HETATM 13088 O O    . HOH F 3 .   ? -20.503 33.732  31.100 1.00 39.99 ?  985  HOH B O    1 
HETATM 13089 O O    . HOH F 3 .   ? -31.165 21.917  48.691 1.00 42.67 ?  986  HOH B O    1 
HETATM 13090 O O    . HOH F 3 .   ? -15.371 51.549  63.894 1.00 30.19 ?  987  HOH B O    1 
HETATM 13091 O O    . HOH F 3 .   ? 16.416  48.235  49.325 1.00 39.18 ?  988  HOH B O    1 
HETATM 13092 O O    . HOH F 3 .   ? 10.990  55.925  39.410 1.00 39.92 ?  989  HOH B O    1 
HETATM 13093 O O    . HOH F 3 .   ? -22.957 32.390  73.020 1.00 36.17 ?  990  HOH B O    1 
HETATM 13094 O O    . HOH F 3 .   ? 13.497  52.290  51.218 1.00 41.02 ?  991  HOH B O    1 
HETATM 13095 O O    . HOH F 3 .   ? 3.891   29.999  66.488 1.00 20.83 ?  992  HOH B O    1 
HETATM 13096 O O    . HOH F 3 .   ? 0.435   53.306  31.560 1.00 42.27 ?  993  HOH B O    1 
HETATM 13097 O O    . HOH F 3 .   ? 19.108  49.048  46.274 1.00 43.49 ?  994  HOH B O    1 
HETATM 13098 O O    . HOH F 3 .   ? -10.188 16.722  55.682 1.00 43.18 ?  995  HOH B O    1 
HETATM 13099 O O    . HOH F 3 .   ? 11.265  53.075  34.649 1.00 32.74 ?  996  HOH B O    1 
HETATM 13100 O O    . HOH F 3 .   ? 2.484   42.163  64.541 1.00 43.91 ?  997  HOH B O    1 
HETATM 13101 O O    . HOH F 3 .   ? -28.616 26.862  34.758 1.00 32.83 ?  998  HOH B O    1 
HETATM 13102 O O    . HOH F 3 .   ? -10.774 30.924  44.276 1.00 26.05 ?  999  HOH B O    1 
HETATM 13103 O O    . HOH F 3 .   ? -23.317 55.560  38.446 1.00 34.31 ?  1000 HOH B O    1 
HETATM 13104 O O    . HOH F 3 .   ? -31.855 41.324  59.431 1.00 34.13 ?  1001 HOH B O    1 
HETATM 13105 O O    . HOH F 3 .   ? 9.989   36.393  21.945 1.00 35.37 ?  1002 HOH B O    1 
HETATM 13106 O O    . HOH F 3 .   ? 4.234   50.057  29.168 1.00 22.09 ?  1003 HOH B O    1 
HETATM 13107 O O    . HOH F 3 .   ? 0.039   47.298  23.037 1.00 44.13 ?  1004 HOH B O    1 
HETATM 13108 O O    . HOH F 3 .   ? 4.146   53.651  54.735 1.00 35.45 ?  1005 HOH B O    1 
HETATM 13109 O O    . HOH F 3 .   ? 3.985   44.066  20.820 1.00 34.97 ?  1006 HOH B O    1 
HETATM 13110 O O    . HOH F 3 .   ? -16.673 21.955  32.574 1.00 16.89 ?  1007 HOH B O    1 
HETATM 13111 O O    . HOH F 3 .   ? -2.844  52.904  33.982 1.00 32.22 ?  1008 HOH B O    1 
HETATM 13112 O O    . HOH F 3 .   ? -13.132 21.899  74.958 1.00 28.00 ?  1009 HOH B O    1 
HETATM 13113 O O    . HOH F 3 .   ? 2.090   43.241  67.079 1.00 39.74 ?  1010 HOH B O    1 
HETATM 13114 O O    . HOH F 3 .   ? 4.329   51.723  57.258 1.00 38.28 ?  1011 HOH B O    1 
HETATM 13115 O O    . HOH F 3 .   ? -10.807 58.563  55.972 1.00 36.97 ?  1012 HOH B O    1 
HETATM 13116 O O    . HOH F 3 .   ? -18.297 31.730  77.725 1.00 34.36 ?  1013 HOH B O    1 
HETATM 13117 O O    . HOH F 3 .   ? 19.292  36.663  27.978 1.00 43.40 ?  1014 HOH B O    1 
HETATM 13118 O O    . HOH F 3 .   ? -28.528 36.929  41.270 1.00 40.70 ?  1015 HOH B O    1 
HETATM 13119 O O    . HOH F 3 .   ? 6.138   19.596  55.919 1.00 31.57 ?  1016 HOH B O    1 
HETATM 13120 O O    . HOH F 3 .   ? -23.462 36.164  36.324 1.00 24.31 ?  1017 HOH B O    1 
HETATM 13121 O O    . HOH F 3 .   ? -21.538 62.843  45.209 1.00 36.83 ?  1018 HOH B O    1 
HETATM 13122 O O    . HOH F 3 .   ? 1.435   58.979  36.572 1.00 41.06 ?  1019 HOH B O    1 
HETATM 13123 O O    . HOH F 3 .   ? -26.594 52.111  30.001 1.00 41.43 ?  1020 HOH B O    1 
HETATM 13124 O O    . HOH F 3 .   ? -1.507  31.127  26.915 1.00 44.30 ?  1021 HOH B O    1 
HETATM 13125 O O    . HOH F 3 .   ? 20.769  41.311  35.364 1.00 41.12 ?  1022 HOH B O    1 
HETATM 13126 O O    . HOH F 3 .   ? -23.114 37.690  32.528 1.00 39.32 ?  1023 HOH B O    1 
HETATM 13127 O O    . HOH F 3 .   ? -13.502 26.499  35.781 1.00 25.75 ?  1024 HOH B O    1 
HETATM 13128 O O    . HOH F 3 .   ? 16.078  27.652  61.038 1.00 25.42 ?  1025 HOH B O    1 
HETATM 13129 O O    . HOH F 3 .   ? 8.237   37.813  19.362 1.00 45.87 ?  1026 HOH B O    1 
HETATM 13130 O O    . HOH F 3 .   ? 10.637  56.208  41.838 1.00 47.65 ?  1027 HOH B O    1 
HETATM 13131 O O    . HOH F 3 .   ? 18.226  50.585  36.818 1.00 40.79 ?  1028 HOH B O    1 
HETATM 13132 O O    . HOH F 3 .   ? 13.297  29.044  54.676 1.00 31.30 ?  1029 HOH B O    1 
HETATM 13133 O O    . HOH F 3 .   ? -29.097 28.625  63.330 1.00 37.29 ?  1030 HOH B O    1 
HETATM 13134 O O    . HOH F 3 .   ? 9.172   39.272  67.704 1.00 42.14 ?  1031 HOH B O    1 
HETATM 13135 O O    . HOH F 3 .   ? 13.848  37.118  55.464 1.00 33.44 ?  1032 HOH B O    1 
HETATM 13136 O O    . HOH F 3 .   ? -12.393 27.679  47.529 1.00 39.47 ?  1033 HOH B O    1 
HETATM 13137 O O    . HOH F 3 .   ? 12.788  48.283  24.306 1.00 46.42 ?  1034 HOH B O    1 
HETATM 13138 O O    . HOH F 3 .   ? -7.798  48.197  66.298 1.00 39.09 ?  1035 HOH B O    1 
HETATM 13139 O O    . HOH F 3 .   ? 7.415   48.243  27.296 1.00 31.60 ?  1036 HOH B O    1 
HETATM 13140 O O    . HOH F 3 .   ? -20.361 15.525  36.860 1.00 38.75 ?  1037 HOH B O    1 
HETATM 13141 O O    . HOH F 3 .   ? -10.043 28.512  46.995 1.00 24.27 ?  1038 HOH B O    1 
HETATM 13142 O O    . HOH F 3 .   ? -22.015 37.681  30.664 1.00 36.91 ?  1039 HOH B O    1 
HETATM 13143 O O    . HOH F 3 .   ? 0.140   35.339  69.357 1.00 34.13 ?  1040 HOH B O    1 
HETATM 13144 O O    . HOH F 3 .   ? 22.203  31.207  33.361 1.00 45.14 ?  1041 HOH B O    1 
HETATM 13145 O O    . HOH F 3 .   ? 12.789  30.396  25.220 1.00 33.90 ?  1042 HOH B O    1 
HETATM 13146 O O    . HOH F 3 .   ? -30.336 44.626  44.217 1.00 42.57 ?  1043 HOH B O    1 
HETATM 13147 O O    . HOH F 3 .   ? -29.669 30.981  60.065 1.00 28.66 ?  1044 HOH B O    1 
HETATM 13148 O O    . HOH F 3 .   ? -36.932 27.305  48.871 1.00 26.49 ?  1045 HOH B O    1 
HETATM 13149 O O    . HOH F 3 .   ? -2.452  33.675  28.134 1.00 40.01 ?  1046 HOH B O    1 
HETATM 13150 O O    . HOH F 3 .   ? 3.029   48.149  62.697 1.00 35.87 ?  1047 HOH B O    1 
HETATM 13151 O O    . HOH F 3 .   ? 7.630   30.424  24.188 1.00 33.42 ?  1048 HOH B O    1 
HETATM 13152 O O    . HOH F 3 .   ? -0.621  39.292  70.549 1.00 43.07 ?  1049 HOH B O    1 
HETATM 13153 O O    . HOH F 3 .   ? 11.916  22.931  34.148 1.00 43.20 ?  1050 HOH B O    1 
HETATM 13154 O O    . HOH F 3 .   ? 14.623  31.464  53.779 1.00 38.70 ?  1051 HOH B O    1 
HETATM 13155 O O    . HOH F 3 .   ? -15.442 48.021  21.238 1.00 29.34 ?  1052 HOH B O    1 
HETATM 13156 O O    . HOH F 3 .   ? -37.547 30.709  52.046 1.00 29.87 ?  1053 HOH B O    1 
HETATM 13157 O O    . HOH F 3 .   ? -13.937 13.885  69.046 1.00 43.68 ?  1054 HOH B O    1 
HETATM 13158 O O    . HOH F 3 .   ? -32.599 22.826  46.608 1.00 38.80 ?  1055 HOH B O    1 
HETATM 13159 O O    . HOH F 3 .   ? 12.586  54.134  47.363 1.00 31.64 ?  1056 HOH B O    1 
HETATM 13160 O O    . HOH F 3 .   ? 11.362  48.985  28.429 1.00 45.37 ?  1057 HOH B O    1 
HETATM 13161 O O    . HOH F 3 .   ? -16.245 51.189  67.963 1.00 37.66 ?  1058 HOH B O    1 
HETATM 13162 O O    . HOH F 3 .   ? -22.474 48.382  54.416 1.00 40.13 ?  1059 HOH B O    1 
HETATM 13163 O O    . HOH F 3 .   ? 14.939  50.314  32.963 1.00 28.80 ?  1060 HOH B O    1 
HETATM 13164 O O    . HOH F 3 .   ? -9.221  16.154  73.167 1.00 44.66 ?  1061 HOH B O    1 
HETATM 13165 O O    . HOH F 3 .   ? -23.302 26.252  34.476 1.00 39.19 ?  1062 HOH B O    1 
HETATM 13166 O O    . HOH F 3 .   ? 12.336  36.552  60.374 1.00 47.43 ?  1063 HOH B O    1 
HETATM 13167 O O    . HOH F 3 .   ? -31.540 44.498  65.003 1.00 39.24 ?  1064 HOH B O    1 
HETATM 13168 O O    . HOH F 3 .   ? 8.817   22.621  38.129 1.00 36.27 ?  1065 HOH B O    1 
HETATM 13169 O O    . HOH F 3 .   ? 15.586  27.167  63.585 1.00 19.51 ?  1066 HOH B O    1 
HETATM 13170 O O    . HOH F 3 .   ? -9.861  17.427  59.973 1.00 39.68 ?  1067 HOH B O    1 
HETATM 13171 O O    . HOH F 3 .   ? 12.984  48.177  29.576 1.00 35.33 ?  1068 HOH B O    1 
HETATM 13172 O O    . HOH F 3 .   ? 13.962  52.758  34.011 1.00 38.70 ?  1069 HOH B O    1 
HETATM 13173 O O    . HOH F 3 .   ? 5.889   22.201  37.825 1.00 42.72 ?  1070 HOH B O    1 
HETATM 13174 O O    . HOH F 3 .   ? 1.332   47.272  67.670 1.00 44.54 ?  1071 HOH B O    1 
HETATM 13175 O O    . HOH F 3 .   ? 9.137   21.700  55.334 1.00 29.87 ?  1072 HOH B O    1 
HETATM 13176 O O    . HOH F 3 .   ? 13.630  34.043  22.807 1.00 34.80 ?  1073 HOH B O    1 
HETATM 13177 O O    . HOH F 3 .   ? 16.998  19.608  28.054 1.00 32.68 ?  1074 HOH B O    1 
HETATM 13178 O O    . HOH F 3 .   ? -18.859 50.837  66.487 1.00 33.89 ?  1075 HOH B O    1 
HETATM 13179 O O    . HOH F 3 .   ? -24.114 51.434  49.865 1.00 41.37 ?  1076 HOH B O    1 
HETATM 13180 O O    . HOH F 3 .   ? -7.104  33.589  27.105 1.00 39.37 ?  1077 HOH B O    1 
HETATM 13181 O O    . HOH F 3 .   ? -18.640 45.787  24.099 1.00 25.49 ?  1078 HOH B O    1 
HETATM 13182 O O    . HOH F 3 .   ? -36.982 28.049  51.301 1.00 29.74 ?  1079 HOH B O    1 
HETATM 13183 O O    . HOH F 3 .   ? 5.198   19.675  53.262 1.00 23.50 ?  1080 HOH B O    1 
HETATM 13184 O O    . HOH F 3 .   ? -2.856  34.672  71.849 1.00 36.08 ?  1081 HOH B O    1 
HETATM 13185 O O    . HOH F 3 .   ? 16.020  41.649  54.181 1.00 47.97 ?  1082 HOH B O    1 
HETATM 13186 O O    . HOH F 3 .   ? 15.617  35.267  56.190 1.00 47.98 ?  1083 HOH B O    1 
HETATM 13187 O O    . HOH F 3 .   ? 19.050  46.810  31.270 1.00 47.02 ?  1084 HOH B O    1 
HETATM 13188 O O    . HOH F 3 .   ? -29.097 17.301  41.303 1.00 46.20 ?  1085 HOH B O    1 
HETATM 13189 O O    . HOH F 3 .   ? 20.956  31.273  36.004 1.00 38.53 ?  1086 HOH B O    1 
HETATM 13190 O O    . HOH F 3 .   ? -2.743  25.807  37.777 1.00 25.82 ?  1087 HOH B O    1 
HETATM 13191 O O    . HOH F 3 .   ? -27.393 38.200  37.163 1.00 37.39 ?  1088 HOH B O    1 
HETATM 13192 O O    . HOH F 3 .   ? -2.935  26.527  50.099 1.00 29.01 ?  1089 HOH B O    1 
HETATM 13193 O O    . HOH F 3 .   ? 13.345  26.524  53.479 1.00 31.47 ?  1090 HOH B O    1 
HETATM 13194 O O    . HOH F 3 .   ? 0.228   59.767  43.081 1.00 29.12 ?  1091 HOH B O    1 
HETATM 13195 O O    . HOH F 3 .   ? 13.926  19.531  24.574 1.00 33.62 ?  1092 HOH B O    1 
HETATM 13196 O O    . HOH F 3 .   ? -15.842 50.197  70.597 1.00 41.60 ?  1093 HOH B O    1 
HETATM 13197 O O    . HOH F 3 .   ? 12.930  39.491  55.926 1.00 42.34 ?  1094 HOH B O    1 
HETATM 13198 O O    . HOH F 3 .   ? 8.223   50.882  31.517 1.00 26.09 ?  1095 HOH B O    1 
HETATM 13199 O O    . HOH F 3 .   ? -26.672 44.411  47.012 1.00 37.28 ?  1096 HOH B O    1 
HETATM 13200 O O    . HOH F 3 .   ? -0.203  34.305  71.653 1.00 42.04 ?  1097 HOH B O    1 
HETATM 13201 O O    . HOH F 3 .   ? 2.267   50.885  66.079 1.00 41.27 ?  1098 HOH B O    1 
HETATM 13202 O O    . HOH F 3 .   ? -24.725 27.908  35.985 1.00 31.58 ?  1099 HOH B O    1 
HETATM 13203 O O    . HOH F 3 .   ? -17.335 21.913  38.701 1.00 43.20 ?  1100 HOH B O    1 
HETATM 13204 O O    . HOH F 3 .   ? 9.082   34.530  25.457 1.00 32.27 ?  1101 HOH B O    1 
HETATM 13205 O O    . HOH F 3 .   ? -17.920 15.318  36.468 1.00 37.13 ?  1102 HOH B O    1 
HETATM 13206 O O    . HOH F 3 .   ? -16.859 23.698  36.495 1.00 29.02 ?  1103 HOH B O    1 
HETATM 13207 O O    . HOH F 3 .   ? 2.762   51.939  59.925 1.00 32.01 ?  1104 HOH B O    1 
HETATM 13208 O O    . HOH F 3 .   ? -25.433 40.957  31.014 1.00 43.66 ?  1105 HOH B O    1 
HETATM 13209 O O    . HOH F 3 .   ? -37.402 25.407  61.072 1.00 40.38 ?  1106 HOH B O    1 
HETATM 13210 O O    . HOH F 3 .   ? -32.178 40.839  62.534 1.00 43.32 ?  1107 HOH B O    1 
HETATM 13211 O O    . HOH F 3 .   ? 6.492   33.847  26.504 1.00 26.66 ?  1108 HOH B O    1 
HETATM 13212 O O    . HOH F 3 .   ? 17.483  46.694  28.871 1.00 44.65 ?  1109 HOH B O    1 
HETATM 13213 O O    . HOH F 3 .   ? 15.101  35.710  22.281 1.00 32.64 ?  1110 HOH B O    1 
HETATM 13214 O O    . HOH F 3 .   ? -6.333  29.470  43.395 1.00 17.85 ?  1111 HOH B O    1 
HETATM 13215 O O    . HOH F 3 .   ? -14.100 33.810  80.109 1.00 42.43 ?  1112 HOH B O    1 
HETATM 13216 O O    . HOH F 3 .   ? 2.772   59.510  41.355 1.00 44.33 ?  1113 HOH B O    1 
HETATM 13217 O O    . HOH F 3 .   ? -14.920 24.499  41.385 1.00 52.13 ?  1114 HOH B O    1 
HETATM 13218 O O    . HOH F 3 .   ? -11.745 26.019  37.952 1.00 43.51 ?  1115 HOH B O    1 
HETATM 13219 O O    . HOH F 3 .   ? -16.544 23.427  41.186 1.00 50.24 ?  1116 HOH B O    1 
HETATM 13220 O O    . HOH F 3 .   ? 5.180   34.429  24.094 1.00 37.32 ?  1117 HOH B O    1 
HETATM 13221 O O    . HOH F 3 .   ? 16.017  26.631  52.866 1.00 34.94 ?  1118 HOH B O    1 
HETATM 13222 O O    . HOH F 3 .   ? -4.453  27.673  44.264 1.00 15.67 ?  1119 HOH B O    1 
HETATM 13223 O O    . HOH F 3 .   ? -6.605  26.665  47.041 1.00 37.69 ?  1120 HOH B O    1 
HETATM 13224 O O    . HOH F 3 .   ? 8.973   49.520  29.244 1.00 36.37 ?  1121 HOH B O    1 
HETATM 13225 O O    . HOH F 3 .   ? 18.123  28.711  62.022 1.00 41.84 ?  1122 HOH B O    1 
HETATM 13226 O O    . HOH F 3 .   ? -5.784  31.174  30.982 1.00 30.80 ?  1123 HOH B O    1 
HETATM 13227 O O    . HOH F 3 .   ? 16.403  50.651  30.786 1.00 44.96 ?  1124 HOH B O    1 
HETATM 13228 O O    . HOH F 3 .   ? -4.954  26.192  46.368 1.00 43.48 ?  1125 HOH B O    1 
HETATM 13229 O O    . HOH F 3 .   ? 8.999   32.738  23.658 1.00 36.24 ?  1126 HOH B O    1 
HETATM 13230 O O    . HOH F 3 .   ? 9.670   19.194  53.870 1.00 45.42 ?  1127 HOH B O    1 
HETATM 13231 O O    . HOH F 3 .   ? -8.765  28.499  43.264 1.00 27.53 ?  1128 HOH B O    1 
HETATM 13232 O O    . HOH F 3 .   ? -8.761  26.555  45.853 1.00 33.34 ?  1129 HOH B O    1 
HETATM 13233 O O    . HOH F 3 .   ? -13.879 20.345  35.543 1.00 24.72 ?  1130 HOH B O    1 
HETATM 13234 O O    . HOH F 3 .   ? -14.550 20.398  38.121 1.00 37.11 ?  1131 HOH B O    1 
HETATM 13235 O O    . HOH F 3 .   ? -9.289  25.257  38.206 1.00 32.53 ?  1132 HOH B O    1 
# 
