data_9JOG
# 
_entry.id   9JOG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JOG         pdb_00009jog 10.2210/pdb9jog/pdb 
WWPDB D_1300051844 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JOG 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              changyg@ouc.edu.cn 
_pdbx_contact_author.name_first         Yaoguang 
_pdbx_contact_author.name_last          Chang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8234-7272 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chen, G.N.'  1 ? 
'Chang, Y.G.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Complex structure of endo-1.3-fucanase (Fun168D) with fucotetraose from Holothuria tubulosa at 1.40 Angstroms resulution.' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Chen, G.N.'  1 ? 
primary 'Chang, Y.G.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man endo-1.3-fucanase 48005.340 2    ? ? ? ? 
2 branched syn 
;2,4-di-O-sulfo-alpha-L-fucopyranose-(1-3)-alpha-L-fucopyranose-(1-3)-2-O-sulfo-alpha-L-fucopyranose-(1-3)-2-O-sulfo-alpha-L-fucopyranose
;
922.833   2    ? ? ? ? 
3 water    nat water 18.015    1405 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSSTKNGIIELEQETEEELEQNQEIDYSNYPEFSWDTMPLYMHVRKNT
AYTDEEINYLASFPLITLEKSQAQNTYGSTEEGTLATASAIKLKNNKAKVLYYRNVVINWGNYKNDDEFISKNPSALLKN
QNNELVYMPNGSTPFFDITKSFVQEYWLKSVEDMVATPNIDGTFIDANIKVLVPSFFSSKVGVNKQAEIENSYFSMMSRL
KESLSNNLILANIIRVRPEFEENGLEYLGYFNGSYLEGFDSEAFGMSNAEYLVEGIEATQKAAQSGKIITMTLGLGEAID
NNTGIDDQREDVDLNDEELNKRVDYLLAIFLICAEKYSYVYLHDGYLATNSAVWLHQFDQYKKALGAPLGKAIKNGYIYT
RKFENLDVWLNLETQTATLTWKE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSSTKNGIIELEQETEEELEQNQEIDYSNYPEFSWDTMPLYMHVRKNT
AYTDEEINYLASFPLITLEKSQAQNTYGSTEEGTLATASAIKLKNNKAKVLYYRNVVINWGNYKNDDEFISKNPSALLKN
QNNELVYMPNGSTPFFDITKSFVQEYWLKSVEDMVATPNIDGTFIDANIKVLVPSFFSSKVGVNKQAEIENSYFSMMSRL
KESLSNNLILANIIRVRPEFEENGLEYLGYFNGSYLEGFDSEAFGMSNAEYLVEGIEATQKAAQSGKIITMTLGLGEAID
NNTGIDDQREDVDLNDEELNKRVDYLLAIFLICAEKYSYVYLHDGYLATNSAVWLHQFDQYKKALGAPLGKAIKNGYIYT
RKFENLDVWLNLETQTATLTWKE
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  ALA n 
1 23  SER n 
1 24  MET n 
1 25  THR n 
1 26  GLY n 
1 27  GLY n 
1 28  GLN n 
1 29  GLN n 
1 30  MET n 
1 31  GLY n 
1 32  ARG n 
1 33  GLY n 
1 34  SER n 
1 35  SER n 
1 36  THR n 
1 37  LYS n 
1 38  ASN n 
1 39  GLY n 
1 40  ILE n 
1 41  ILE n 
1 42  GLU n 
1 43  LEU n 
1 44  GLU n 
1 45  GLN n 
1 46  GLU n 
1 47  THR n 
1 48  GLU n 
1 49  GLU n 
1 50  GLU n 
1 51  LEU n 
1 52  GLU n 
1 53  GLN n 
1 54  ASN n 
1 55  GLN n 
1 56  GLU n 
1 57  ILE n 
1 58  ASP n 
1 59  TYR n 
1 60  SER n 
1 61  ASN n 
1 62  TYR n 
1 63  PRO n 
1 64  GLU n 
1 65  PHE n 
1 66  SER n 
1 67  TRP n 
1 68  ASP n 
1 69  THR n 
1 70  MET n 
1 71  PRO n 
1 72  LEU n 
1 73  TYR n 
1 74  MET n 
1 75  HIS n 
1 76  VAL n 
1 77  ARG n 
1 78  LYS n 
1 79  ASN n 
1 80  THR n 
1 81  ALA n 
1 82  TYR n 
1 83  THR n 
1 84  ASP n 
1 85  GLU n 
1 86  GLU n 
1 87  ILE n 
1 88  ASN n 
1 89  TYR n 
1 90  LEU n 
1 91  ALA n 
1 92  SER n 
1 93  PHE n 
1 94  PRO n 
1 95  LEU n 
1 96  ILE n 
1 97  THR n 
1 98  LEU n 
1 99  GLU n 
1 100 LYS n 
1 101 SER n 
1 102 GLN n 
1 103 ALA n 
1 104 GLN n 
1 105 ASN n 
1 106 THR n 
1 107 TYR n 
1 108 GLY n 
1 109 SER n 
1 110 THR n 
1 111 GLU n 
1 112 GLU n 
1 113 GLY n 
1 114 THR n 
1 115 LEU n 
1 116 ALA n 
1 117 THR n 
1 118 ALA n 
1 119 SER n 
1 120 ALA n 
1 121 ILE n 
1 122 LYS n 
1 123 LEU n 
1 124 LYS n 
1 125 ASN n 
1 126 ASN n 
1 127 LYS n 
1 128 ALA n 
1 129 LYS n 
1 130 VAL n 
1 131 LEU n 
1 132 TYR n 
1 133 TYR n 
1 134 ARG n 
1 135 ASN n 
1 136 VAL n 
1 137 VAL n 
1 138 ILE n 
1 139 ASN n 
1 140 TRP n 
1 141 GLY n 
1 142 ASN n 
1 143 TYR n 
1 144 LYS n 
1 145 ASN n 
1 146 ASP n 
1 147 ASP n 
1 148 GLU n 
1 149 PHE n 
1 150 ILE n 
1 151 SER n 
1 152 LYS n 
1 153 ASN n 
1 154 PRO n 
1 155 SER n 
1 156 ALA n 
1 157 LEU n 
1 158 LEU n 
1 159 LYS n 
1 160 ASN n 
1 161 GLN n 
1 162 ASN n 
1 163 ASN n 
1 164 GLU n 
1 165 LEU n 
1 166 VAL n 
1 167 TYR n 
1 168 MET n 
1 169 PRO n 
1 170 ASN n 
1 171 GLY n 
1 172 SER n 
1 173 THR n 
1 174 PRO n 
1 175 PHE n 
1 176 PHE n 
1 177 ASP n 
1 178 ILE n 
1 179 THR n 
1 180 LYS n 
1 181 SER n 
1 182 PHE n 
1 183 VAL n 
1 184 GLN n 
1 185 GLU n 
1 186 TYR n 
1 187 TRP n 
1 188 LEU n 
1 189 LYS n 
1 190 SER n 
1 191 VAL n 
1 192 GLU n 
1 193 ASP n 
1 194 MET n 
1 195 VAL n 
1 196 ALA n 
1 197 THR n 
1 198 PRO n 
1 199 ASN n 
1 200 ILE n 
1 201 ASP n 
1 202 GLY n 
1 203 THR n 
1 204 PHE n 
1 205 ILE n 
1 206 ASP n 
1 207 ALA n 
1 208 ASN n 
1 209 ILE n 
1 210 LYS n 
1 211 VAL n 
1 212 LEU n 
1 213 VAL n 
1 214 PRO n 
1 215 SER n 
1 216 PHE n 
1 217 PHE n 
1 218 SER n 
1 219 SER n 
1 220 LYS n 
1 221 VAL n 
1 222 GLY n 
1 223 VAL n 
1 224 ASN n 
1 225 LYS n 
1 226 GLN n 
1 227 ALA n 
1 228 GLU n 
1 229 ILE n 
1 230 GLU n 
1 231 ASN n 
1 232 SER n 
1 233 TYR n 
1 234 PHE n 
1 235 SER n 
1 236 MET n 
1 237 MET n 
1 238 SER n 
1 239 ARG n 
1 240 LEU n 
1 241 LYS n 
1 242 GLU n 
1 243 SER n 
1 244 LEU n 
1 245 SER n 
1 246 ASN n 
1 247 ASN n 
1 248 LEU n 
1 249 ILE n 
1 250 LEU n 
1 251 ALA n 
1 252 ASN n 
1 253 ILE n 
1 254 ILE n 
1 255 ARG n 
1 256 VAL n 
1 257 ARG n 
1 258 PRO n 
1 259 GLU n 
1 260 PHE n 
1 261 GLU n 
1 262 GLU n 
1 263 ASN n 
1 264 GLY n 
1 265 LEU n 
1 266 GLU n 
1 267 TYR n 
1 268 LEU n 
1 269 GLY n 
1 270 TYR n 
1 271 PHE n 
1 272 ASN n 
1 273 GLY n 
1 274 SER n 
1 275 TYR n 
1 276 LEU n 
1 277 GLU n 
1 278 GLY n 
1 279 PHE n 
1 280 ASP n 
1 281 SER n 
1 282 GLU n 
1 283 ALA n 
1 284 PHE n 
1 285 GLY n 
1 286 MET n 
1 287 SER n 
1 288 ASN n 
1 289 ALA n 
1 290 GLU n 
1 291 TYR n 
1 292 LEU n 
1 293 VAL n 
1 294 GLU n 
1 295 GLY n 
1 296 ILE n 
1 297 GLU n 
1 298 ALA n 
1 299 THR n 
1 300 GLN n 
1 301 LYS n 
1 302 ALA n 
1 303 ALA n 
1 304 GLN n 
1 305 SER n 
1 306 GLY n 
1 307 LYS n 
1 308 ILE n 
1 309 ILE n 
1 310 THR n 
1 311 MET n 
1 312 THR n 
1 313 LEU n 
1 314 GLY n 
1 315 LEU n 
1 316 GLY n 
1 317 GLU n 
1 318 ALA n 
1 319 ILE n 
1 320 ASP n 
1 321 ASN n 
1 322 ASN n 
1 323 THR n 
1 324 GLY n 
1 325 ILE n 
1 326 ASP n 
1 327 ASP n 
1 328 GLN n 
1 329 ARG n 
1 330 GLU n 
1 331 ASP n 
1 332 VAL n 
1 333 ASP n 
1 334 LEU n 
1 335 ASN n 
1 336 ASP n 
1 337 GLU n 
1 338 GLU n 
1 339 LEU n 
1 340 ASN n 
1 341 LYS n 
1 342 ARG n 
1 343 VAL n 
1 344 ASP n 
1 345 TYR n 
1 346 LEU n 
1 347 LEU n 
1 348 ALA n 
1 349 ILE n 
1 350 PHE n 
1 351 LEU n 
1 352 ILE n 
1 353 CYS n 
1 354 ALA n 
1 355 GLU n 
1 356 LYS n 
1 357 TYR n 
1 358 SER n 
1 359 TYR n 
1 360 VAL n 
1 361 TYR n 
1 362 LEU n 
1 363 HIS n 
1 364 ASP n 
1 365 GLY n 
1 366 TYR n 
1 367 LEU n 
1 368 ALA n 
1 369 THR n 
1 370 ASN n 
1 371 SER n 
1 372 ALA n 
1 373 VAL n 
1 374 TRP n 
1 375 LEU n 
1 376 HIS n 
1 377 GLN n 
1 378 PHE n 
1 379 ASP n 
1 380 GLN n 
1 381 TYR n 
1 382 LYS n 
1 383 LYS n 
1 384 ALA n 
1 385 LEU n 
1 386 GLY n 
1 387 ALA n 
1 388 PRO n 
1 389 LEU n 
1 390 GLY n 
1 391 LYS n 
1 392 ALA n 
1 393 ILE n 
1 394 LYS n 
1 395 ASN n 
1 396 GLY n 
1 397 TYR n 
1 398 ILE n 
1 399 TYR n 
1 400 THR n 
1 401 ARG n 
1 402 LYS n 
1 403 PHE n 
1 404 GLU n 
1 405 ASN n 
1 406 LEU n 
1 407 ASP n 
1 408 VAL n 
1 409 TRP n 
1 410 LEU n 
1 411 ASN n 
1 412 LEU n 
1 413 GLU n 
1 414 THR n 
1 415 GLN n 
1 416 THR n 
1 417 ALA n 
1 418 THR n 
1 419 LEU n 
1 420 THR n 
1 421 TRP n 
1 422 LYS n 
1 423 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   423 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 AXE80_08865 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Wenyingzhuangia fucanilytica' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1790137 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_branch.entity_id   2 
_pdbx_entity_branch.type        oligosaccharide 
# 
_pdbx_entity_branch_descriptor.ordinal           1 
_pdbx_entity_branch_descriptor.entity_id         2 
_pdbx_entity_branch_descriptor.descriptor        
'[][a-L-Fucp2SO3]{[(3+1)][a-L-Fucp2SO3]{[(3+1)][a-L-Fucp]{[(3+1)][a-L-Fucp2SO34SO3]{}}}}' 
_pdbx_entity_branch_descriptor.type              LINUCS 
_pdbx_entity_branch_descriptor.program           PDB-CARE 
_pdbx_entity_branch_descriptor.program_version   ? 
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 X6Y C1 H1 1 X6Y O3 HO3 sing ? 
2 2 3 FUC C1 O1 2 X6Y O3 HO3 sing ? 
3 2 4 X2Y C1 O1 3 FUC O3 HO3 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                             ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                            ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                          ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                     ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'           y CYSTEINE                            ? 'C3 H7 N O2 S'   121.158 
FUC 'L-saccharide, alpha linking' . alpha-L-fucopyranose                
'alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose' 'C6 H12 O5'      164.156 
GLN 'L-peptide linking'           y GLUTAMINE                           ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                     ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                             ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                           ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                               ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                          ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                             ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                              ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                          ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking'           y PHENYLALANINE                       ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                             ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                              ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                           ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                          ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                            ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                              ? 'C5 H11 N O2'    117.146 
X2Y 'L-saccharide, alpha linking' n 2,4-di-O-sulfo-alpha-L-fucopyranose 6-deoxy-2,4-di-O-sulfo-alpha-L-galactopyranose 
'C6 H12 O11 S2'  324.283 
X6Y 'L-saccharide, alpha linking' n 2-O-sulfo-alpha-L-fucopyranose      6-deoxy-2-O-sulfo-alpha-L-galactopyranose 'C6 H12 O8 S'    
244.220 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
FUC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LFucpa           
FUC 'COMMON NAME'                         GMML     1.0 a-L-fucopyranose 
FUC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Fucp         
FUC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fuc              
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -33 ?   ?   ?   A . n 
A 1 2   GLY 2   -32 ?   ?   ?   A . n 
A 1 3   SER 3   -31 ?   ?   ?   A . n 
A 1 4   SER 4   -30 ?   ?   ?   A . n 
A 1 5   HIS 5   -29 ?   ?   ?   A . n 
A 1 6   HIS 6   -28 ?   ?   ?   A . n 
A 1 7   HIS 7   -27 ?   ?   ?   A . n 
A 1 8   HIS 8   -26 ?   ?   ?   A . n 
A 1 9   HIS 9   -25 ?   ?   ?   A . n 
A 1 10  HIS 10  -24 ?   ?   ?   A . n 
A 1 11  SER 11  -23 ?   ?   ?   A . n 
A 1 12  SER 12  -22 ?   ?   ?   A . n 
A 1 13  GLY 13  -21 ?   ?   ?   A . n 
A 1 14  LEU 14  -20 ?   ?   ?   A . n 
A 1 15  VAL 15  -19 ?   ?   ?   A . n 
A 1 16  PRO 16  -18 ?   ?   ?   A . n 
A 1 17  ARG 17  -17 ?   ?   ?   A . n 
A 1 18  GLY 18  -16 ?   ?   ?   A . n 
A 1 19  SER 19  -15 ?   ?   ?   A . n 
A 1 20  HIS 20  -14 ?   ?   ?   A . n 
A 1 21  MET 21  -13 ?   ?   ?   A . n 
A 1 22  ALA 22  -12 ?   ?   ?   A . n 
A 1 23  SER 23  -11 ?   ?   ?   A . n 
A 1 24  MET 24  -10 ?   ?   ?   A . n 
A 1 25  THR 25  -9  ?   ?   ?   A . n 
A 1 26  GLY 26  -8  ?   ?   ?   A . n 
A 1 27  GLY 27  -7  ?   ?   ?   A . n 
A 1 28  GLN 28  -6  ?   ?   ?   A . n 
A 1 29  GLN 29  -5  ?   ?   ?   A . n 
A 1 30  MET 30  -4  ?   ?   ?   A . n 
A 1 31  GLY 31  -3  ?   ?   ?   A . n 
A 1 32  ARG 32  -2  ?   ?   ?   A . n 
A 1 33  GLY 33  -1  ?   ?   ?   A . n 
A 1 34  SER 34  0   ?   ?   ?   A . n 
A 1 35  SER 35  1   ?   ?   ?   A . n 
A 1 36  THR 36  2   ?   ?   ?   A . n 
A 1 37  LYS 37  3   ?   ?   ?   A . n 
A 1 38  ASN 38  4   ?   ?   ?   A . n 
A 1 39  GLY 39  5   ?   ?   ?   A . n 
A 1 40  ILE 40  6   ?   ?   ?   A . n 
A 1 41  ILE 41  7   ?   ?   ?   A . n 
A 1 42  GLU 42  8   ?   ?   ?   A . n 
A 1 43  LEU 43  9   ?   ?   ?   A . n 
A 1 44  GLU 44  10  ?   ?   ?   A . n 
A 1 45  GLN 45  11  ?   ?   ?   A . n 
A 1 46  GLU 46  12  ?   ?   ?   A . n 
A 1 47  THR 47  13  ?   ?   ?   A . n 
A 1 48  GLU 48  14  ?   ?   ?   A . n 
A 1 49  GLU 49  15  ?   ?   ?   A . n 
A 1 50  GLU 50  16  ?   ?   ?   A . n 
A 1 51  LEU 51  17  17  LEU LEU A . n 
A 1 52  GLU 52  18  18  GLU GLU A . n 
A 1 53  GLN 53  19  19  GLN GLN A . n 
A 1 54  ASN 54  20  20  ASN ASN A . n 
A 1 55  GLN 55  21  21  GLN GLN A . n 
A 1 56  GLU 56  22  22  GLU GLU A . n 
A 1 57  ILE 57  23  23  ILE ILE A . n 
A 1 58  ASP 58  24  24  ASP ASP A . n 
A 1 59  TYR 59  25  25  TYR TYR A . n 
A 1 60  SER 60  26  26  SER SER A . n 
A 1 61  ASN 61  27  27  ASN ASN A . n 
A 1 62  TYR 62  28  28  TYR TYR A . n 
A 1 63  PRO 63  29  29  PRO PRO A . n 
A 1 64  GLU 64  30  30  GLU GLU A . n 
A 1 65  PHE 65  31  31  PHE PHE A . n 
A 1 66  SER 66  32  32  SER SER A . n 
A 1 67  TRP 67  33  33  TRP TRP A . n 
A 1 68  ASP 68  34  34  ASP ASP A . n 
A 1 69  THR 69  35  35  THR THR A . n 
A 1 70  MET 70  36  36  MET MET A . n 
A 1 71  PRO 71  37  37  PRO PRO A . n 
A 1 72  LEU 72  38  38  LEU LEU A . n 
A 1 73  TYR 73  39  39  TYR TYR A . n 
A 1 74  MET 74  40  40  MET MET A . n 
A 1 75  HIS 75  41  41  HIS HIS A . n 
A 1 76  VAL 76  42  42  VAL VAL A . n 
A 1 77  ARG 77  43  43  ARG ARG A . n 
A 1 78  LYS 78  44  44  LYS LYS A . n 
A 1 79  ASN 79  45  45  ASN ASN A . n 
A 1 80  THR 80  46  46  THR THR A . n 
A 1 81  ALA 81  47  47  ALA ALA A . n 
A 1 82  TYR 82  48  48  TYR TYR A . n 
A 1 83  THR 83  49  49  THR THR A . n 
A 1 84  ASP 84  50  50  ASP ASP A . n 
A 1 85  GLU 85  51  51  GLU GLU A . n 
A 1 86  GLU 86  52  52  GLU GLU A . n 
A 1 87  ILE 87  53  53  ILE ILE A . n 
A 1 88  ASN 88  54  54  ASN ASN A . n 
A 1 89  TYR 89  55  55  TYR TYR A . n 
A 1 90  LEU 90  56  56  LEU LEU A . n 
A 1 91  ALA 91  57  57  ALA ALA A . n 
A 1 92  SER 92  58  58  SER SER A . n 
A 1 93  PHE 93  59  59  PHE PHE A . n 
A 1 94  PRO 94  60  60  PRO PRO A . n 
A 1 95  LEU 95  61  61  LEU LEU A . n 
A 1 96  ILE 96  62  62  ILE ILE A . n 
A 1 97  THR 97  63  63  THR THR A . n 
A 1 98  LEU 98  64  64  LEU LEU A . n 
A 1 99  GLU 99  65  65  GLU GLU A . n 
A 1 100 LYS 100 66  66  LYS LYS A . n 
A 1 101 SER 101 67  67  SER SER A . n 
A 1 102 GLN 102 68  68  GLN GLN A . n 
A 1 103 ALA 103 69  69  ALA ALA A . n 
A 1 104 GLN 104 70  70  GLN GLN A . n 
A 1 105 ASN 105 71  71  ASN ASN A . n 
A 1 106 THR 106 72  72  THR THR A . n 
A 1 107 TYR 107 73  73  TYR TYR A . n 
A 1 108 GLY 108 74  74  GLY GLY A . n 
A 1 109 SER 109 75  75  SER SER A . n 
A 1 110 THR 110 76  76  THR THR A . n 
A 1 111 GLU 111 77  77  GLU GLU A . n 
A 1 112 GLU 112 78  78  GLU GLU A . n 
A 1 113 GLY 113 79  79  GLY GLY A . n 
A 1 114 THR 114 80  80  THR THR A . n 
A 1 115 LEU 115 81  81  LEU LEU A . n 
A 1 116 ALA 116 82  82  ALA ALA A . n 
A 1 117 THR 117 83  83  THR THR A . n 
A 1 118 ALA 118 84  84  ALA ALA A . n 
A 1 119 SER 119 85  85  SER SER A . n 
A 1 120 ALA 120 86  86  ALA ALA A . n 
A 1 121 ILE 121 87  87  ILE ILE A . n 
A 1 122 LYS 122 88  88  LYS LYS A . n 
A 1 123 LEU 123 89  89  LEU LEU A . n 
A 1 124 LYS 124 90  90  LYS LYS A . n 
A 1 125 ASN 125 91  91  ASN ASN A . n 
A 1 126 ASN 126 92  92  ASN ASN A . n 
A 1 127 LYS 127 93  93  LYS LYS A . n 
A 1 128 ALA 128 94  94  ALA ALA A . n 
A 1 129 LYS 129 95  95  LYS LYS A . n 
A 1 130 VAL 130 96  96  VAL VAL A . n 
A 1 131 LEU 131 97  97  LEU LEU A . n 
A 1 132 TYR 132 98  98  TYR TYR A . n 
A 1 133 TYR 133 99  99  TYR TYR A . n 
A 1 134 ARG 134 100 100 ARG ARG A . n 
A 1 135 ASN 135 101 101 ASN ASN A . n 
A 1 136 VAL 136 102 102 VAL VAL A . n 
A 1 137 VAL 137 103 103 VAL VAL A . n 
A 1 138 ILE 138 104 104 ILE ILE A . n 
A 1 139 ASN 139 105 105 ASN ASN A . n 
A 1 140 TRP 140 106 106 TRP TRP A . n 
A 1 141 GLY 141 107 107 GLY GLY A . n 
A 1 142 ASN 142 108 108 ASN ASN A . n 
A 1 143 TYR 143 109 109 TYR TYR A . n 
A 1 144 LYS 144 110 110 LYS LYS A . n 
A 1 145 ASN 145 111 111 ASN ASN A . n 
A 1 146 ASP 146 112 112 ASP ASP A . n 
A 1 147 ASP 147 113 113 ASP ASP A . n 
A 1 148 GLU 148 114 114 GLU GLU A . n 
A 1 149 PHE 149 115 115 PHE PHE A . n 
A 1 150 ILE 150 116 116 ILE ILE A . n 
A 1 151 SER 151 117 117 SER SER A . n 
A 1 152 LYS 152 118 118 LYS LYS A . n 
A 1 153 ASN 153 119 119 ASN ASN A . n 
A 1 154 PRO 154 120 120 PRO PRO A . n 
A 1 155 SER 155 121 121 SER SER A . n 
A 1 156 ALA 156 122 122 ALA ALA A . n 
A 1 157 LEU 157 123 123 LEU LEU A . n 
A 1 158 LEU 158 124 124 LEU LEU A . n 
A 1 159 LYS 159 125 125 LYS LYS A . n 
A 1 160 ASN 160 126 126 ASN ASN A . n 
A 1 161 GLN 161 127 127 GLN GLN A . n 
A 1 162 ASN 162 128 128 ASN ASN A . n 
A 1 163 ASN 163 129 129 ASN ASN A . n 
A 1 164 GLU 164 130 130 GLU GLU A . n 
A 1 165 LEU 165 131 131 LEU LEU A . n 
A 1 166 VAL 166 132 132 VAL VAL A . n 
A 1 167 TYR 167 133 133 TYR TYR A . n 
A 1 168 MET 168 134 134 MET MET A . n 
A 1 169 PRO 169 135 135 PRO PRO A . n 
A 1 170 ASN 170 136 136 ASN ASN A . n 
A 1 171 GLY 171 137 137 GLY GLY A . n 
A 1 172 SER 172 138 138 SER SER A . n 
A 1 173 THR 173 139 139 THR THR A . n 
A 1 174 PRO 174 140 140 PRO PRO A . n 
A 1 175 PHE 175 141 141 PHE PHE A . n 
A 1 176 PHE 176 142 142 PHE PHE A . n 
A 1 177 ASP 177 143 143 ASP ASP A . n 
A 1 178 ILE 178 144 144 ILE ILE A . n 
A 1 179 THR 179 145 145 THR THR A . n 
A 1 180 LYS 180 146 146 LYS LYS A . n 
A 1 181 SER 181 147 147 SER SER A . n 
A 1 182 PHE 182 148 148 PHE PHE A . n 
A 1 183 VAL 183 149 149 VAL VAL A . n 
A 1 184 GLN 184 150 150 GLN GLN A . n 
A 1 185 GLU 185 151 151 GLU GLU A . n 
A 1 186 TYR 186 152 152 TYR TYR A . n 
A 1 187 TRP 187 153 153 TRP TRP A . n 
A 1 188 LEU 188 154 154 LEU LEU A . n 
A 1 189 LYS 189 155 155 LYS LYS A . n 
A 1 190 SER 190 156 156 SER SER A . n 
A 1 191 VAL 191 157 157 VAL VAL A . n 
A 1 192 GLU 192 158 158 GLU GLU A . n 
A 1 193 ASP 193 159 159 ASP ASP A . n 
A 1 194 MET 194 160 160 MET MET A . n 
A 1 195 VAL 195 161 161 VAL VAL A . n 
A 1 196 ALA 196 162 162 ALA ALA A . n 
A 1 197 THR 197 163 163 THR THR A . n 
A 1 198 PRO 198 164 164 PRO PRO A . n 
A 1 199 ASN 199 165 165 ASN ASN A . n 
A 1 200 ILE 200 166 166 ILE ILE A . n 
A 1 201 ASP 201 167 167 ASP ASP A . n 
A 1 202 GLY 202 168 168 GLY GLY A . n 
A 1 203 THR 203 169 169 THR THR A . n 
A 1 204 PHE 204 170 170 PHE PHE A . n 
A 1 205 ILE 205 171 171 ILE ILE A . n 
A 1 206 ASP 206 172 172 ASP ASP A . n 
A 1 207 ALA 207 173 173 ALA ALA A . n 
A 1 208 ASN 208 174 174 ASN ASN A . n 
A 1 209 ILE 209 175 175 ILE ILE A . n 
A 1 210 LYS 210 176 176 LYS LYS A . n 
A 1 211 VAL 211 177 177 VAL VAL A . n 
A 1 212 LEU 212 178 178 LEU LEU A . n 
A 1 213 VAL 213 179 179 VAL VAL A . n 
A 1 214 PRO 214 180 180 PRO PRO A . n 
A 1 215 SER 215 181 181 SER SER A . n 
A 1 216 PHE 216 182 182 PHE PHE A . n 
A 1 217 PHE 217 183 183 PHE PHE A . n 
A 1 218 SER 218 184 184 SER SER A . n 
A 1 219 SER 219 185 185 SER SER A . n 
A 1 220 LYS 220 186 186 LYS LYS A . n 
A 1 221 VAL 221 187 187 VAL VAL A . n 
A 1 222 GLY 222 188 188 GLY GLY A . n 
A 1 223 VAL 223 189 189 VAL VAL A . n 
A 1 224 ASN 224 190 190 ASN ASN A . n 
A 1 225 LYS 225 191 191 LYS LYS A . n 
A 1 226 GLN 226 192 192 GLN GLN A . n 
A 1 227 ALA 227 193 193 ALA ALA A . n 
A 1 228 GLU 228 194 194 GLU GLU A . n 
A 1 229 ILE 229 195 195 ILE ILE A . n 
A 1 230 GLU 230 196 196 GLU GLU A . n 
A 1 231 ASN 231 197 197 ASN ASN A . n 
A 1 232 SER 232 198 198 SER SER A . n 
A 1 233 TYR 233 199 199 TYR TYR A . n 
A 1 234 PHE 234 200 200 PHE PHE A . n 
A 1 235 SER 235 201 201 SER SER A . n 
A 1 236 MET 236 202 202 MET MET A . n 
A 1 237 MET 237 203 203 MET MET A . n 
A 1 238 SER 238 204 204 SER SER A . n 
A 1 239 ARG 239 205 205 ARG ARG A . n 
A 1 240 LEU 240 206 206 LEU LEU A . n 
A 1 241 LYS 241 207 207 LYS LYS A . n 
A 1 242 GLU 242 208 208 GLU GLU A . n 
A 1 243 SER 243 209 209 SER SER A . n 
A 1 244 LEU 244 210 210 LEU LEU A . n 
A 1 245 SER 245 211 211 SER SER A . n 
A 1 246 ASN 246 212 212 ASN ASN A . n 
A 1 247 ASN 247 213 213 ASN ASN A . n 
A 1 248 LEU 248 214 214 LEU LEU A . n 
A 1 249 ILE 249 215 215 ILE ILE A . n 
A 1 250 LEU 250 216 216 LEU LEU A . n 
A 1 251 ALA 251 217 217 ALA ALA A . n 
A 1 252 ASN 252 218 218 ASN ASN A . n 
A 1 253 ILE 253 219 219 ILE ILE A . n 
A 1 254 ILE 254 220 220 ILE ILE A . n 
A 1 255 ARG 255 221 221 ARG ARG A . n 
A 1 256 VAL 256 222 222 VAL VAL A . n 
A 1 257 ARG 257 223 223 ARG ARG A . n 
A 1 258 PRO 258 224 224 PRO PRO A . n 
A 1 259 GLU 259 225 225 GLU GLU A . n 
A 1 260 PHE 260 226 226 PHE PHE A . n 
A 1 261 GLU 261 227 227 GLU GLU A . n 
A 1 262 GLU 262 228 228 GLU GLU A . n 
A 1 263 ASN 263 229 229 ASN ASN A . n 
A 1 264 GLY 264 230 230 GLY GLY A . n 
A 1 265 LEU 265 231 231 LEU LEU A . n 
A 1 266 GLU 266 232 232 GLU GLU A . n 
A 1 267 TYR 267 233 233 TYR TYR A . n 
A 1 268 LEU 268 234 234 LEU LEU A . n 
A 1 269 GLY 269 235 235 GLY GLY A . n 
A 1 270 TYR 270 236 236 TYR TYR A . n 
A 1 271 PHE 271 237 237 PHE PHE A . n 
A 1 272 ASN 272 238 238 ASN ASN A . n 
A 1 273 GLY 273 239 239 GLY GLY A . n 
A 1 274 SER 274 240 240 SER SER A . n 
A 1 275 TYR 275 241 241 TYR TYR A . n 
A 1 276 LEU 276 242 242 LEU LEU A . n 
A 1 277 GLU 277 243 243 GLU GLU A . n 
A 1 278 GLY 278 244 244 GLY GLY A . n 
A 1 279 PHE 279 245 245 PHE PHE A . n 
A 1 280 ASP 280 246 246 ASP ASP A . n 
A 1 281 SER 281 247 247 SER SER A . n 
A 1 282 GLU 282 248 248 GLU GLU A . n 
A 1 283 ALA 283 249 249 ALA ALA A . n 
A 1 284 PHE 284 250 250 PHE PHE A . n 
A 1 285 GLY 285 251 251 GLY GLY A . n 
A 1 286 MET 286 252 252 MET MET A . n 
A 1 287 SER 287 253 253 SER SER A . n 
A 1 288 ASN 288 254 254 ASN ASN A . n 
A 1 289 ALA 289 255 255 ALA ALA A . n 
A 1 290 GLU 290 256 256 GLU GLU A . n 
A 1 291 TYR 291 257 257 TYR TYR A . n 
A 1 292 LEU 292 258 258 LEU LEU A . n 
A 1 293 VAL 293 259 259 VAL VAL A . n 
A 1 294 GLU 294 260 260 GLU GLU A . n 
A 1 295 GLY 295 261 261 GLY GLY A . n 
A 1 296 ILE 296 262 262 ILE ILE A . n 
A 1 297 GLU 297 263 263 GLU GLU A . n 
A 1 298 ALA 298 264 264 ALA ALA A . n 
A 1 299 THR 299 265 265 THR THR A . n 
A 1 300 GLN 300 266 266 GLN GLN A . n 
A 1 301 LYS 301 267 267 LYS LYS A . n 
A 1 302 ALA 302 268 268 ALA ALA A . n 
A 1 303 ALA 303 269 269 ALA ALA A . n 
A 1 304 GLN 304 270 270 GLN GLN A . n 
A 1 305 SER 305 271 271 SER SER A . n 
A 1 306 GLY 306 272 272 GLY GLY A . n 
A 1 307 LYS 307 273 273 LYS LYS A . n 
A 1 308 ILE 308 274 274 ILE ILE A . n 
A 1 309 ILE 309 275 275 ILE ILE A . n 
A 1 310 THR 310 276 276 THR THR A . n 
A 1 311 MET 311 277 277 MET MET A . n 
A 1 312 THR 312 278 278 THR THR A . n 
A 1 313 LEU 313 279 279 LEU LEU A . n 
A 1 314 GLY 314 280 280 GLY GLY A . n 
A 1 315 LEU 315 281 281 LEU LEU A . n 
A 1 316 GLY 316 282 282 GLY GLY A . n 
A 1 317 GLU 317 283 283 GLU GLU A . n 
A 1 318 ALA 318 284 284 ALA ALA A . n 
A 1 319 ILE 319 285 285 ILE ILE A . n 
A 1 320 ASP 320 286 286 ASP ASP A . n 
A 1 321 ASN 321 287 287 ASN ASN A . n 
A 1 322 ASN 322 288 288 ASN ASN A . n 
A 1 323 THR 323 289 289 THR THR A . n 
A 1 324 GLY 324 290 290 GLY GLY A . n 
A 1 325 ILE 325 291 291 ILE ILE A . n 
A 1 326 ASP 326 292 292 ASP ASP A . n 
A 1 327 ASP 327 293 293 ASP ASP A . n 
A 1 328 GLN 328 294 294 GLN GLN A . n 
A 1 329 ARG 329 295 295 ARG ARG A . n 
A 1 330 GLU 330 296 296 GLU GLU A . n 
A 1 331 ASP 331 297 297 ASP ASP A . n 
A 1 332 VAL 332 298 298 VAL VAL A . n 
A 1 333 ASP 333 299 299 ASP ASP A . n 
A 1 334 LEU 334 300 300 LEU LEU A . n 
A 1 335 ASN 335 301 301 ASN ASN A . n 
A 1 336 ASP 336 302 302 ASP ASP A . n 
A 1 337 GLU 337 303 303 GLU GLU A . n 
A 1 338 GLU 338 304 304 GLU GLU A . n 
A 1 339 LEU 339 305 305 LEU LEU A . n 
A 1 340 ASN 340 306 306 ASN ASN A . n 
A 1 341 LYS 341 307 307 LYS LYS A . n 
A 1 342 ARG 342 308 308 ARG ARG A . n 
A 1 343 VAL 343 309 309 VAL VAL A . n 
A 1 344 ASP 344 310 310 ASP ASP A . n 
A 1 345 TYR 345 311 311 TYR TYR A . n 
A 1 346 LEU 346 312 312 LEU LEU A . n 
A 1 347 LEU 347 313 313 LEU LEU A . n 
A 1 348 ALA 348 314 314 ALA ALA A . n 
A 1 349 ILE 349 315 315 ILE ILE A . n 
A 1 350 PHE 350 316 316 PHE PHE A . n 
A 1 351 LEU 351 317 317 LEU LEU A . n 
A 1 352 ILE 352 318 318 ILE ILE A . n 
A 1 353 CYS 353 319 319 CYS CYS A . n 
A 1 354 ALA 354 320 320 ALA ALA A . n 
A 1 355 GLU 355 321 321 GLU GLU A . n 
A 1 356 LYS 356 322 322 LYS LYS A . n 
A 1 357 TYR 357 323 323 TYR TYR A . n 
A 1 358 SER 358 324 324 SER SER A . n 
A 1 359 TYR 359 325 325 TYR TYR A . n 
A 1 360 VAL 360 326 326 VAL VAL A . n 
A 1 361 TYR 361 327 327 TYR TYR A . n 
A 1 362 LEU 362 328 328 LEU LEU A . n 
A 1 363 HIS 363 329 329 HIS HIS A . n 
A 1 364 ASP 364 330 330 ASP ASP A . n 
A 1 365 GLY 365 331 331 GLY GLY A . n 
A 1 366 TYR 366 332 332 TYR TYR A . n 
A 1 367 LEU 367 333 333 LEU LEU A . n 
A 1 368 ALA 368 334 334 ALA ALA A . n 
A 1 369 THR 369 335 335 THR THR A . n 
A 1 370 ASN 370 336 336 ASN ASN A . n 
A 1 371 SER 371 337 337 SER SER A . n 
A 1 372 ALA 372 338 338 ALA ALA A . n 
A 1 373 VAL 373 339 339 VAL VAL A . n 
A 1 374 TRP 374 340 340 TRP TRP A . n 
A 1 375 LEU 375 341 341 LEU LEU A . n 
A 1 376 HIS 376 342 342 HIS HIS A . n 
A 1 377 GLN 377 343 343 GLN GLN A . n 
A 1 378 PHE 378 344 344 PHE PHE A . n 
A 1 379 ASP 379 345 345 ASP ASP A . n 
A 1 380 GLN 380 346 346 GLN GLN A . n 
A 1 381 TYR 381 347 347 TYR TYR A . n 
A 1 382 LYS 382 348 348 LYS LYS A . n 
A 1 383 LYS 383 349 349 LYS LYS A . n 
A 1 384 ALA 384 350 350 ALA ALA A . n 
A 1 385 LEU 385 351 351 LEU LEU A . n 
A 1 386 GLY 386 352 352 GLY GLY A . n 
A 1 387 ALA 387 353 353 ALA ALA A . n 
A 1 388 PRO 388 354 354 PRO PRO A . n 
A 1 389 LEU 389 355 355 LEU LEU A . n 
A 1 390 GLY 390 356 356 GLY GLY A . n 
A 1 391 LYS 391 357 357 LYS LYS A . n 
A 1 392 ALA 392 358 358 ALA ALA A . n 
A 1 393 ILE 393 359 359 ILE ILE A . n 
A 1 394 LYS 394 360 360 LYS LYS A . n 
A 1 395 ASN 395 361 361 ASN ASN A . n 
A 1 396 GLY 396 362 362 GLY GLY A . n 
A 1 397 TYR 397 363 363 TYR TYR A . n 
A 1 398 ILE 398 364 364 ILE ILE A . n 
A 1 399 TYR 399 365 365 TYR TYR A . n 
A 1 400 THR 400 366 366 THR THR A . n 
A 1 401 ARG 401 367 367 ARG ARG A . n 
A 1 402 LYS 402 368 368 LYS LYS A . n 
A 1 403 PHE 403 369 369 PHE PHE A . n 
A 1 404 GLU 404 370 370 GLU GLU A . n 
A 1 405 ASN 405 371 371 ASN ASN A . n 
A 1 406 LEU 406 372 372 LEU LEU A . n 
A 1 407 ASP 407 373 373 ASP ASP A . n 
A 1 408 VAL 408 374 374 VAL VAL A . n 
A 1 409 TRP 409 375 375 TRP TRP A . n 
A 1 410 LEU 410 376 376 LEU LEU A . n 
A 1 411 ASN 411 377 377 ASN ASN A . n 
A 1 412 LEU 412 378 378 LEU LEU A . n 
A 1 413 GLU 413 379 379 GLU GLU A . n 
A 1 414 THR 414 380 380 THR THR A . n 
A 1 415 GLN 415 381 381 GLN GLN A . n 
A 1 416 THR 416 382 382 THR THR A . n 
A 1 417 ALA 417 383 383 ALA ALA A . n 
A 1 418 THR 418 384 384 THR THR A . n 
A 1 419 LEU 419 385 385 LEU LEU A . n 
A 1 420 THR 420 386 386 THR THR A . n 
A 1 421 TRP 421 387 387 TRP TRP A . n 
A 1 422 LYS 422 388 388 LYS LYS A . n 
A 1 423 GLU 423 389 ?   ?   ?   A . n 
B 1 1   MET 1   -33 ?   ?   ?   B . n 
B 1 2   GLY 2   -32 ?   ?   ?   B . n 
B 1 3   SER 3   -31 ?   ?   ?   B . n 
B 1 4   SER 4   -30 ?   ?   ?   B . n 
B 1 5   HIS 5   -29 ?   ?   ?   B . n 
B 1 6   HIS 6   -28 ?   ?   ?   B . n 
B 1 7   HIS 7   -27 ?   ?   ?   B . n 
B 1 8   HIS 8   -26 ?   ?   ?   B . n 
B 1 9   HIS 9   -25 ?   ?   ?   B . n 
B 1 10  HIS 10  -24 ?   ?   ?   B . n 
B 1 11  SER 11  -23 ?   ?   ?   B . n 
B 1 12  SER 12  -22 ?   ?   ?   B . n 
B 1 13  GLY 13  -21 ?   ?   ?   B . n 
B 1 14  LEU 14  -20 ?   ?   ?   B . n 
B 1 15  VAL 15  -19 ?   ?   ?   B . n 
B 1 16  PRO 16  -18 ?   ?   ?   B . n 
B 1 17  ARG 17  -17 ?   ?   ?   B . n 
B 1 18  GLY 18  -16 ?   ?   ?   B . n 
B 1 19  SER 19  -15 ?   ?   ?   B . n 
B 1 20  HIS 20  -14 ?   ?   ?   B . n 
B 1 21  MET 21  -13 ?   ?   ?   B . n 
B 1 22  ALA 22  -12 ?   ?   ?   B . n 
B 1 23  SER 23  -11 ?   ?   ?   B . n 
B 1 24  MET 24  -10 ?   ?   ?   B . n 
B 1 25  THR 25  -9  ?   ?   ?   B . n 
B 1 26  GLY 26  -8  ?   ?   ?   B . n 
B 1 27  GLY 27  -7  ?   ?   ?   B . n 
B 1 28  GLN 28  -6  ?   ?   ?   B . n 
B 1 29  GLN 29  -5  ?   ?   ?   B . n 
B 1 30  MET 30  -4  ?   ?   ?   B . n 
B 1 31  GLY 31  -3  ?   ?   ?   B . n 
B 1 32  ARG 32  -2  ?   ?   ?   B . n 
B 1 33  GLY 33  -1  ?   ?   ?   B . n 
B 1 34  SER 34  0   ?   ?   ?   B . n 
B 1 35  SER 35  1   ?   ?   ?   B . n 
B 1 36  THR 36  2   ?   ?   ?   B . n 
B 1 37  LYS 37  3   ?   ?   ?   B . n 
B 1 38  ASN 38  4   ?   ?   ?   B . n 
B 1 39  GLY 39  5   ?   ?   ?   B . n 
B 1 40  ILE 40  6   ?   ?   ?   B . n 
B 1 41  ILE 41  7   ?   ?   ?   B . n 
B 1 42  GLU 42  8   ?   ?   ?   B . n 
B 1 43  LEU 43  9   ?   ?   ?   B . n 
B 1 44  GLU 44  10  ?   ?   ?   B . n 
B 1 45  GLN 45  11  ?   ?   ?   B . n 
B 1 46  GLU 46  12  ?   ?   ?   B . n 
B 1 47  THR 47  13  ?   ?   ?   B . n 
B 1 48  GLU 48  14  ?   ?   ?   B . n 
B 1 49  GLU 49  15  ?   ?   ?   B . n 
B 1 50  GLU 50  16  ?   ?   ?   B . n 
B 1 51  LEU 51  17  ?   ?   ?   B . n 
B 1 52  GLU 52  18  ?   ?   ?   B . n 
B 1 53  GLN 53  19  ?   ?   ?   B . n 
B 1 54  ASN 54  20  ?   ?   ?   B . n 
B 1 55  GLN 55  21  ?   ?   ?   B . n 
B 1 56  GLU 56  22  ?   ?   ?   B . n 
B 1 57  ILE 57  23  23  ILE ILE B . n 
B 1 58  ASP 58  24  24  ASP ASP B . n 
B 1 59  TYR 59  25  25  TYR TYR B . n 
B 1 60  SER 60  26  26  SER SER B . n 
B 1 61  ASN 61  27  27  ASN ASN B . n 
B 1 62  TYR 62  28  28  TYR TYR B . n 
B 1 63  PRO 63  29  29  PRO PRO B . n 
B 1 64  GLU 64  30  30  GLU GLU B . n 
B 1 65  PHE 65  31  31  PHE PHE B . n 
B 1 66  SER 66  32  32  SER SER B . n 
B 1 67  TRP 67  33  33  TRP TRP B . n 
B 1 68  ASP 68  34  34  ASP ASP B . n 
B 1 69  THR 69  35  35  THR THR B . n 
B 1 70  MET 70  36  36  MET MET B . n 
B 1 71  PRO 71  37  37  PRO PRO B . n 
B 1 72  LEU 72  38  38  LEU LEU B . n 
B 1 73  TYR 73  39  39  TYR TYR B . n 
B 1 74  MET 74  40  40  MET MET B . n 
B 1 75  HIS 75  41  41  HIS HIS B . n 
B 1 76  VAL 76  42  42  VAL VAL B . n 
B 1 77  ARG 77  43  43  ARG ARG B . n 
B 1 78  LYS 78  44  44  LYS LYS B . n 
B 1 79  ASN 79  45  45  ASN ASN B . n 
B 1 80  THR 80  46  46  THR THR B . n 
B 1 81  ALA 81  47  47  ALA ALA B . n 
B 1 82  TYR 82  48  48  TYR TYR B . n 
B 1 83  THR 83  49  49  THR THR B . n 
B 1 84  ASP 84  50  50  ASP ASP B . n 
B 1 85  GLU 85  51  51  GLU GLU B . n 
B 1 86  GLU 86  52  52  GLU GLU B . n 
B 1 87  ILE 87  53  53  ILE ILE B . n 
B 1 88  ASN 88  54  54  ASN ASN B . n 
B 1 89  TYR 89  55  55  TYR TYR B . n 
B 1 90  LEU 90  56  56  LEU LEU B . n 
B 1 91  ALA 91  57  57  ALA ALA B . n 
B 1 92  SER 92  58  58  SER SER B . n 
B 1 93  PHE 93  59  59  PHE PHE B . n 
B 1 94  PRO 94  60  60  PRO PRO B . n 
B 1 95  LEU 95  61  61  LEU LEU B . n 
B 1 96  ILE 96  62  62  ILE ILE B . n 
B 1 97  THR 97  63  63  THR THR B . n 
B 1 98  LEU 98  64  64  LEU LEU B . n 
B 1 99  GLU 99  65  65  GLU GLU B . n 
B 1 100 LYS 100 66  66  LYS LYS B . n 
B 1 101 SER 101 67  67  SER SER B . n 
B 1 102 GLN 102 68  68  GLN GLN B . n 
B 1 103 ALA 103 69  69  ALA ALA B . n 
B 1 104 GLN 104 70  70  GLN GLN B . n 
B 1 105 ASN 105 71  71  ASN ASN B . n 
B 1 106 THR 106 72  72  THR THR B . n 
B 1 107 TYR 107 73  73  TYR TYR B . n 
B 1 108 GLY 108 74  74  GLY GLY B . n 
B 1 109 SER 109 75  75  SER SER B . n 
B 1 110 THR 110 76  76  THR THR B . n 
B 1 111 GLU 111 77  77  GLU GLU B . n 
B 1 112 GLU 112 78  78  GLU GLU B . n 
B 1 113 GLY 113 79  79  GLY GLY B . n 
B 1 114 THR 114 80  80  THR THR B . n 
B 1 115 LEU 115 81  81  LEU LEU B . n 
B 1 116 ALA 116 82  82  ALA ALA B . n 
B 1 117 THR 117 83  83  THR THR B . n 
B 1 118 ALA 118 84  84  ALA ALA B . n 
B 1 119 SER 119 85  85  SER SER B . n 
B 1 120 ALA 120 86  86  ALA ALA B . n 
B 1 121 ILE 121 87  87  ILE ILE B . n 
B 1 122 LYS 122 88  88  LYS LYS B . n 
B 1 123 LEU 123 89  89  LEU LEU B . n 
B 1 124 LYS 124 90  90  LYS LYS B . n 
B 1 125 ASN 125 91  91  ASN ASN B . n 
B 1 126 ASN 126 92  92  ASN ASN B . n 
B 1 127 LYS 127 93  93  LYS LYS B . n 
B 1 128 ALA 128 94  94  ALA ALA B . n 
B 1 129 LYS 129 95  95  LYS LYS B . n 
B 1 130 VAL 130 96  96  VAL VAL B . n 
B 1 131 LEU 131 97  97  LEU LEU B . n 
B 1 132 TYR 132 98  98  TYR TYR B . n 
B 1 133 TYR 133 99  99  TYR TYR B . n 
B 1 134 ARG 134 100 100 ARG ARG B . n 
B 1 135 ASN 135 101 101 ASN ASN B . n 
B 1 136 VAL 136 102 102 VAL VAL B . n 
B 1 137 VAL 137 103 103 VAL VAL B . n 
B 1 138 ILE 138 104 104 ILE ILE B . n 
B 1 139 ASN 139 105 105 ASN ASN B . n 
B 1 140 TRP 140 106 106 TRP TRP B . n 
B 1 141 GLY 141 107 107 GLY GLY B . n 
B 1 142 ASN 142 108 108 ASN ASN B . n 
B 1 143 TYR 143 109 109 TYR TYR B . n 
B 1 144 LYS 144 110 110 LYS LYS B . n 
B 1 145 ASN 145 111 111 ASN ASN B . n 
B 1 146 ASP 146 112 112 ASP ASP B . n 
B 1 147 ASP 147 113 113 ASP ASP B . n 
B 1 148 GLU 148 114 114 GLU GLU B . n 
B 1 149 PHE 149 115 115 PHE PHE B . n 
B 1 150 ILE 150 116 116 ILE ILE B . n 
B 1 151 SER 151 117 117 SER SER B . n 
B 1 152 LYS 152 118 118 LYS LYS B . n 
B 1 153 ASN 153 119 119 ASN ASN B . n 
B 1 154 PRO 154 120 120 PRO PRO B . n 
B 1 155 SER 155 121 121 SER SER B . n 
B 1 156 ALA 156 122 122 ALA ALA B . n 
B 1 157 LEU 157 123 123 LEU LEU B . n 
B 1 158 LEU 158 124 124 LEU LEU B . n 
B 1 159 LYS 159 125 125 LYS LYS B . n 
B 1 160 ASN 160 126 126 ASN ASN B . n 
B 1 161 GLN 161 127 127 GLN GLN B . n 
B 1 162 ASN 162 128 128 ASN ASN B . n 
B 1 163 ASN 163 129 129 ASN ASN B . n 
B 1 164 GLU 164 130 130 GLU GLU B . n 
B 1 165 LEU 165 131 131 LEU LEU B . n 
B 1 166 VAL 166 132 132 VAL VAL B . n 
B 1 167 TYR 167 133 133 TYR TYR B . n 
B 1 168 MET 168 134 134 MET MET B . n 
B 1 169 PRO 169 135 135 PRO PRO B . n 
B 1 170 ASN 170 136 136 ASN ASN B . n 
B 1 171 GLY 171 137 137 GLY GLY B . n 
B 1 172 SER 172 138 138 SER SER B . n 
B 1 173 THR 173 139 139 THR THR B . n 
B 1 174 PRO 174 140 140 PRO PRO B . n 
B 1 175 PHE 175 141 141 PHE PHE B . n 
B 1 176 PHE 176 142 142 PHE PHE B . n 
B 1 177 ASP 177 143 143 ASP ASP B . n 
B 1 178 ILE 178 144 144 ILE ILE B . n 
B 1 179 THR 179 145 145 THR THR B . n 
B 1 180 LYS 180 146 146 LYS LYS B . n 
B 1 181 SER 181 147 147 SER SER B . n 
B 1 182 PHE 182 148 148 PHE PHE B . n 
B 1 183 VAL 183 149 149 VAL VAL B . n 
B 1 184 GLN 184 150 150 GLN GLN B . n 
B 1 185 GLU 185 151 151 GLU GLU B . n 
B 1 186 TYR 186 152 152 TYR TYR B . n 
B 1 187 TRP 187 153 153 TRP TRP B . n 
B 1 188 LEU 188 154 154 LEU LEU B . n 
B 1 189 LYS 189 155 155 LYS LYS B . n 
B 1 190 SER 190 156 156 SER SER B . n 
B 1 191 VAL 191 157 157 VAL VAL B . n 
B 1 192 GLU 192 158 158 GLU GLU B . n 
B 1 193 ASP 193 159 159 ASP ASP B . n 
B 1 194 MET 194 160 160 MET MET B . n 
B 1 195 VAL 195 161 161 VAL VAL B . n 
B 1 196 ALA 196 162 162 ALA ALA B . n 
B 1 197 THR 197 163 163 THR THR B . n 
B 1 198 PRO 198 164 164 PRO PRO B . n 
B 1 199 ASN 199 165 165 ASN ASN B . n 
B 1 200 ILE 200 166 166 ILE ILE B . n 
B 1 201 ASP 201 167 167 ASP ASP B . n 
B 1 202 GLY 202 168 168 GLY GLY B . n 
B 1 203 THR 203 169 169 THR THR B . n 
B 1 204 PHE 204 170 170 PHE PHE B . n 
B 1 205 ILE 205 171 171 ILE ILE B . n 
B 1 206 ASP 206 172 172 ASP ASP B . n 
B 1 207 ALA 207 173 173 ALA ALA B . n 
B 1 208 ASN 208 174 174 ASN ASN B . n 
B 1 209 ILE 209 175 175 ILE ILE B . n 
B 1 210 LYS 210 176 176 LYS LYS B . n 
B 1 211 VAL 211 177 177 VAL VAL B . n 
B 1 212 LEU 212 178 178 LEU LEU B . n 
B 1 213 VAL 213 179 179 VAL VAL B . n 
B 1 214 PRO 214 180 180 PRO PRO B . n 
B 1 215 SER 215 181 181 SER SER B . n 
B 1 216 PHE 216 182 182 PHE PHE B . n 
B 1 217 PHE 217 183 183 PHE PHE B . n 
B 1 218 SER 218 184 184 SER SER B . n 
B 1 219 SER 219 185 185 SER SER B . n 
B 1 220 LYS 220 186 186 LYS LYS B . n 
B 1 221 VAL 221 187 187 VAL VAL B . n 
B 1 222 GLY 222 188 188 GLY GLY B . n 
B 1 223 VAL 223 189 189 VAL VAL B . n 
B 1 224 ASN 224 190 190 ASN ASN B . n 
B 1 225 LYS 225 191 191 LYS LYS B . n 
B 1 226 GLN 226 192 192 GLN GLN B . n 
B 1 227 ALA 227 193 193 ALA ALA B . n 
B 1 228 GLU 228 194 194 GLU GLU B . n 
B 1 229 ILE 229 195 195 ILE ILE B . n 
B 1 230 GLU 230 196 196 GLU GLU B . n 
B 1 231 ASN 231 197 197 ASN ASN B . n 
B 1 232 SER 232 198 198 SER SER B . n 
B 1 233 TYR 233 199 199 TYR TYR B . n 
B 1 234 PHE 234 200 200 PHE PHE B . n 
B 1 235 SER 235 201 201 SER SER B . n 
B 1 236 MET 236 202 202 MET MET B . n 
B 1 237 MET 237 203 203 MET MET B . n 
B 1 238 SER 238 204 204 SER SER B . n 
B 1 239 ARG 239 205 205 ARG ARG B . n 
B 1 240 LEU 240 206 206 LEU LEU B . n 
B 1 241 LYS 241 207 207 LYS LYS B . n 
B 1 242 GLU 242 208 208 GLU GLU B . n 
B 1 243 SER 243 209 209 SER SER B . n 
B 1 244 LEU 244 210 210 LEU LEU B . n 
B 1 245 SER 245 211 211 SER SER B . n 
B 1 246 ASN 246 212 212 ASN ASN B . n 
B 1 247 ASN 247 213 213 ASN ASN B . n 
B 1 248 LEU 248 214 214 LEU LEU B . n 
B 1 249 ILE 249 215 215 ILE ILE B . n 
B 1 250 LEU 250 216 216 LEU LEU B . n 
B 1 251 ALA 251 217 217 ALA ALA B . n 
B 1 252 ASN 252 218 218 ASN ASN B . n 
B 1 253 ILE 253 219 219 ILE ILE B . n 
B 1 254 ILE 254 220 220 ILE ILE B . n 
B 1 255 ARG 255 221 221 ARG ARG B . n 
B 1 256 VAL 256 222 222 VAL VAL B . n 
B 1 257 ARG 257 223 223 ARG ARG B . n 
B 1 258 PRO 258 224 224 PRO PRO B . n 
B 1 259 GLU 259 225 225 GLU GLU B . n 
B 1 260 PHE 260 226 226 PHE PHE B . n 
B 1 261 GLU 261 227 227 GLU GLU B . n 
B 1 262 GLU 262 228 228 GLU GLU B . n 
B 1 263 ASN 263 229 229 ASN ASN B . n 
B 1 264 GLY 264 230 230 GLY GLY B . n 
B 1 265 LEU 265 231 231 LEU LEU B . n 
B 1 266 GLU 266 232 232 GLU GLU B . n 
B 1 267 TYR 267 233 233 TYR TYR B . n 
B 1 268 LEU 268 234 234 LEU LEU B . n 
B 1 269 GLY 269 235 235 GLY GLY B . n 
B 1 270 TYR 270 236 236 TYR TYR B . n 
B 1 271 PHE 271 237 237 PHE PHE B . n 
B 1 272 ASN 272 238 238 ASN ASN B . n 
B 1 273 GLY 273 239 239 GLY GLY B . n 
B 1 274 SER 274 240 240 SER SER B . n 
B 1 275 TYR 275 241 241 TYR TYR B . n 
B 1 276 LEU 276 242 242 LEU LEU B . n 
B 1 277 GLU 277 243 243 GLU GLU B . n 
B 1 278 GLY 278 244 244 GLY GLY B . n 
B 1 279 PHE 279 245 245 PHE PHE B . n 
B 1 280 ASP 280 246 246 ASP ASP B . n 
B 1 281 SER 281 247 247 SER SER B . n 
B 1 282 GLU 282 248 248 GLU GLU B . n 
B 1 283 ALA 283 249 249 ALA ALA B . n 
B 1 284 PHE 284 250 250 PHE PHE B . n 
B 1 285 GLY 285 251 251 GLY GLY B . n 
B 1 286 MET 286 252 252 MET MET B . n 
B 1 287 SER 287 253 253 SER SER B . n 
B 1 288 ASN 288 254 254 ASN ASN B . n 
B 1 289 ALA 289 255 255 ALA ALA B . n 
B 1 290 GLU 290 256 256 GLU GLU B . n 
B 1 291 TYR 291 257 257 TYR TYR B . n 
B 1 292 LEU 292 258 258 LEU LEU B . n 
B 1 293 VAL 293 259 259 VAL VAL B . n 
B 1 294 GLU 294 260 260 GLU GLU B . n 
B 1 295 GLY 295 261 261 GLY GLY B . n 
B 1 296 ILE 296 262 262 ILE ILE B . n 
B 1 297 GLU 297 263 263 GLU GLU B . n 
B 1 298 ALA 298 264 264 ALA ALA B . n 
B 1 299 THR 299 265 265 THR THR B . n 
B 1 300 GLN 300 266 266 GLN GLN B . n 
B 1 301 LYS 301 267 267 LYS LYS B . n 
B 1 302 ALA 302 268 268 ALA ALA B . n 
B 1 303 ALA 303 269 269 ALA ALA B . n 
B 1 304 GLN 304 270 270 GLN GLN B . n 
B 1 305 SER 305 271 271 SER SER B . n 
B 1 306 GLY 306 272 272 GLY GLY B . n 
B 1 307 LYS 307 273 273 LYS LYS B . n 
B 1 308 ILE 308 274 274 ILE ILE B . n 
B 1 309 ILE 309 275 275 ILE ILE B . n 
B 1 310 THR 310 276 276 THR THR B . n 
B 1 311 MET 311 277 277 MET MET B . n 
B 1 312 THR 312 278 278 THR THR B . n 
B 1 313 LEU 313 279 279 LEU LEU B . n 
B 1 314 GLY 314 280 280 GLY GLY B . n 
B 1 315 LEU 315 281 281 LEU LEU B . n 
B 1 316 GLY 316 282 282 GLY GLY B . n 
B 1 317 GLU 317 283 283 GLU GLU B . n 
B 1 318 ALA 318 284 284 ALA ALA B . n 
B 1 319 ILE 319 285 285 ILE ILE B . n 
B 1 320 ASP 320 286 286 ASP ASP B . n 
B 1 321 ASN 321 287 287 ASN ASN B . n 
B 1 322 ASN 322 288 288 ASN ASN B . n 
B 1 323 THR 323 289 289 THR THR B . n 
B 1 324 GLY 324 290 290 GLY GLY B . n 
B 1 325 ILE 325 291 291 ILE ILE B . n 
B 1 326 ASP 326 292 292 ASP ASP B . n 
B 1 327 ASP 327 293 293 ASP ASP B . n 
B 1 328 GLN 328 294 294 GLN GLN B . n 
B 1 329 ARG 329 295 295 ARG ARG B . n 
B 1 330 GLU 330 296 296 GLU GLU B . n 
B 1 331 ASP 331 297 297 ASP ASP B . n 
B 1 332 VAL 332 298 298 VAL VAL B . n 
B 1 333 ASP 333 299 299 ASP ASP B . n 
B 1 334 LEU 334 300 300 LEU LEU B . n 
B 1 335 ASN 335 301 301 ASN ASN B . n 
B 1 336 ASP 336 302 302 ASP ASP B . n 
B 1 337 GLU 337 303 303 GLU GLU B . n 
B 1 338 GLU 338 304 304 GLU GLU B . n 
B 1 339 LEU 339 305 305 LEU LEU B . n 
B 1 340 ASN 340 306 306 ASN ASN B . n 
B 1 341 LYS 341 307 307 LYS LYS B . n 
B 1 342 ARG 342 308 308 ARG ARG B . n 
B 1 343 VAL 343 309 309 VAL VAL B . n 
B 1 344 ASP 344 310 310 ASP ASP B . n 
B 1 345 TYR 345 311 311 TYR TYR B . n 
B 1 346 LEU 346 312 312 LEU LEU B . n 
B 1 347 LEU 347 313 313 LEU LEU B . n 
B 1 348 ALA 348 314 314 ALA ALA B . n 
B 1 349 ILE 349 315 315 ILE ILE B . n 
B 1 350 PHE 350 316 316 PHE PHE B . n 
B 1 351 LEU 351 317 317 LEU LEU B . n 
B 1 352 ILE 352 318 318 ILE ILE B . n 
B 1 353 CYS 353 319 319 CYS CYS B . n 
B 1 354 ALA 354 320 320 ALA ALA B . n 
B 1 355 GLU 355 321 321 GLU GLU B . n 
B 1 356 LYS 356 322 322 LYS LYS B . n 
B 1 357 TYR 357 323 323 TYR TYR B . n 
B 1 358 SER 358 324 324 SER SER B . n 
B 1 359 TYR 359 325 325 TYR TYR B . n 
B 1 360 VAL 360 326 326 VAL VAL B . n 
B 1 361 TYR 361 327 327 TYR TYR B . n 
B 1 362 LEU 362 328 328 LEU LEU B . n 
B 1 363 HIS 363 329 329 HIS HIS B . n 
B 1 364 ASP 364 330 330 ASP ASP B . n 
B 1 365 GLY 365 331 331 GLY GLY B . n 
B 1 366 TYR 366 332 332 TYR TYR B . n 
B 1 367 LEU 367 333 333 LEU LEU B . n 
B 1 368 ALA 368 334 334 ALA ALA B . n 
B 1 369 THR 369 335 335 THR THR B . n 
B 1 370 ASN 370 336 336 ASN ASN B . n 
B 1 371 SER 371 337 337 SER SER B . n 
B 1 372 ALA 372 338 338 ALA ALA B . n 
B 1 373 VAL 373 339 339 VAL VAL B . n 
B 1 374 TRP 374 340 340 TRP TRP B . n 
B 1 375 LEU 375 341 341 LEU LEU B . n 
B 1 376 HIS 376 342 342 HIS HIS B . n 
B 1 377 GLN 377 343 343 GLN GLN B . n 
B 1 378 PHE 378 344 344 PHE PHE B . n 
B 1 379 ASP 379 345 345 ASP ASP B . n 
B 1 380 GLN 380 346 346 GLN GLN B . n 
B 1 381 TYR 381 347 347 TYR TYR B . n 
B 1 382 LYS 382 348 348 LYS LYS B . n 
B 1 383 LYS 383 349 349 LYS LYS B . n 
B 1 384 ALA 384 350 350 ALA ALA B . n 
B 1 385 LEU 385 351 351 LEU LEU B . n 
B 1 386 GLY 386 352 352 GLY GLY B . n 
B 1 387 ALA 387 353 353 ALA ALA B . n 
B 1 388 PRO 388 354 354 PRO PRO B . n 
B 1 389 LEU 389 355 355 LEU LEU B . n 
B 1 390 GLY 390 356 356 GLY GLY B . n 
B 1 391 LYS 391 357 357 LYS LYS B . n 
B 1 392 ALA 392 358 358 ALA ALA B . n 
B 1 393 ILE 393 359 359 ILE ILE B . n 
B 1 394 LYS 394 360 360 LYS LYS B . n 
B 1 395 ASN 395 361 361 ASN ASN B . n 
B 1 396 GLY 396 362 362 GLY GLY B . n 
B 1 397 TYR 397 363 363 TYR TYR B . n 
B 1 398 ILE 398 364 364 ILE ILE B . n 
B 1 399 TYR 399 365 365 TYR TYR B . n 
B 1 400 THR 400 366 366 THR THR B . n 
B 1 401 ARG 401 367 367 ARG ARG B . n 
B 1 402 LYS 402 368 368 LYS LYS B . n 
B 1 403 PHE 403 369 369 PHE PHE B . n 
B 1 404 GLU 404 370 370 GLU GLU B . n 
B 1 405 ASN 405 371 371 ASN ASN B . n 
B 1 406 LEU 406 372 372 LEU LEU B . n 
B 1 407 ASP 407 373 373 ASP ASP B . n 
B 1 408 VAL 408 374 374 VAL VAL B . n 
B 1 409 TRP 409 375 375 TRP TRP B . n 
B 1 410 LEU 410 376 376 LEU LEU B . n 
B 1 411 ASN 411 377 377 ASN ASN B . n 
B 1 412 LEU 412 378 378 LEU LEU B . n 
B 1 413 GLU 413 379 379 GLU GLU B . n 
B 1 414 THR 414 380 380 THR THR B . n 
B 1 415 GLN 415 381 381 GLN GLN B . n 
B 1 416 THR 416 382 382 THR THR B . n 
B 1 417 ALA 417 383 383 ALA ALA B . n 
B 1 418 THR 418 384 384 THR THR B . n 
B 1 419 LEU 419 385 385 LEU LEU B . n 
B 1 420 THR 420 386 386 THR THR B . n 
B 1 421 TRP 421 387 387 TRP TRP B . n 
B 1 422 LYS 422 388 388 LYS LYS B . n 
B 1 423 GLU 423 389 ?   ?   ?   B . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 2 X6Y 1 C X6Y 1 A 168 401 n 
C 2 X6Y 2 C X6Y 2 A 168 401 n 
C 2 FUC 3 C FUC 3 A 168 401 n 
C 2 X2Y 4 C X2Y 4 A 168 401 n 
D 2 X6Y 1 D X6Y 1 B 168 401 n 
D 2 X6Y 2 D X6Y 2 B 168 401 n 
D 2 FUC 3 D FUC 3 B 168 401 n 
D 2 X2Y 4 D X2Y 4 B 168 401 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 FUC ? ? FUC ? ? 'SUBJECT OF INVESTIGATION' ? 
2 X2Y ? ? X2Y ? ? 'SUBJECT OF INVESTIGATION' ? 
3 X6Y ? ? X6Y ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 HOH 1   401  1    HOH HOH A . 
E 3 HOH 2   402  1315 HOH HOH A . 
E 3 HOH 3   403  1022 HOH HOH A . 
E 3 HOH 4   404  1246 HOH HOH A . 
E 3 HOH 5   405  1332 HOH HOH A . 
E 3 HOH 6   406  864  HOH HOH A . 
E 3 HOH 7   407  568  HOH HOH A . 
E 3 HOH 8   408  1180 HOH HOH A . 
E 3 HOH 9   409  885  HOH HOH A . 
E 3 HOH 10  410  835  HOH HOH A . 
E 3 HOH 11  411  1064 HOH HOH A . 
E 3 HOH 12  412  823  HOH HOH A . 
E 3 HOH 13  413  634  HOH HOH A . 
E 3 HOH 14  414  429  HOH HOH A . 
E 3 HOH 15  415  1093 HOH HOH A . 
E 3 HOH 16  416  936  HOH HOH A . 
E 3 HOH 17  417  1388 HOH HOH A . 
E 3 HOH 18  418  1092 HOH HOH A . 
E 3 HOH 19  419  211  HOH HOH A . 
E 3 HOH 20  420  340  HOH HOH A . 
E 3 HOH 21  421  643  HOH HOH A . 
E 3 HOH 22  422  1292 HOH HOH A . 
E 3 HOH 23  423  810  HOH HOH A . 
E 3 HOH 24  424  312  HOH HOH A . 
E 3 HOH 25  425  578  HOH HOH A . 
E 3 HOH 26  426  748  HOH HOH A . 
E 3 HOH 27  427  554  HOH HOH A . 
E 3 HOH 28  428  8    HOH HOH A . 
E 3 HOH 29  429  1243 HOH HOH A . 
E 3 HOH 30  430  1372 HOH HOH A . 
E 3 HOH 31  431  1410 HOH HOH A . 
E 3 HOH 32  432  549  HOH HOH A . 
E 3 HOH 33  433  327  HOH HOH A . 
E 3 HOH 34  434  916  HOH HOH A . 
E 3 HOH 35  435  50   HOH HOH A . 
E 3 HOH 36  436  959  HOH HOH A . 
E 3 HOH 37  437  1056 HOH HOH A . 
E 3 HOH 38  438  946  HOH HOH A . 
E 3 HOH 39  439  1244 HOH HOH A . 
E 3 HOH 40  440  330  HOH HOH A . 
E 3 HOH 41  441  308  HOH HOH A . 
E 3 HOH 42  442  505  HOH HOH A . 
E 3 HOH 43  443  344  HOH HOH A . 
E 3 HOH 44  444  987  HOH HOH A . 
E 3 HOH 45  445  118  HOH HOH A . 
E 3 HOH 46  446  172  HOH HOH A . 
E 3 HOH 47  447  772  HOH HOH A . 
E 3 HOH 48  448  390  HOH HOH A . 
E 3 HOH 49  449  721  HOH HOH A . 
E 3 HOH 50  450  551  HOH HOH A . 
E 3 HOH 51  451  1379 HOH HOH A . 
E 3 HOH 52  452  87   HOH HOH A . 
E 3 HOH 53  453  728  HOH HOH A . 
E 3 HOH 54  454  402  HOH HOH A . 
E 3 HOH 55  455  195  HOH HOH A . 
E 3 HOH 56  456  796  HOH HOH A . 
E 3 HOH 57  457  918  HOH HOH A . 
E 3 HOH 58  458  294  HOH HOH A . 
E 3 HOH 59  459  1051 HOH HOH A . 
E 3 HOH 60  460  786  HOH HOH A . 
E 3 HOH 61  461  1084 HOH HOH A . 
E 3 HOH 62  462  85   HOH HOH A . 
E 3 HOH 63  463  4    HOH HOH A . 
E 3 HOH 64  464  419  HOH HOH A . 
E 3 HOH 65  465  125  HOH HOH A . 
E 3 HOH 66  466  462  HOH HOH A . 
E 3 HOH 67  467  1231 HOH HOH A . 
E 3 HOH 68  468  1377 HOH HOH A . 
E 3 HOH 69  469  117  HOH HOH A . 
E 3 HOH 70  470  873  HOH HOH A . 
E 3 HOH 71  471  276  HOH HOH A . 
E 3 HOH 72  472  1074 HOH HOH A . 
E 3 HOH 73  473  10   HOH HOH A . 
E 3 HOH 74  474  865  HOH HOH A . 
E 3 HOH 75  475  3    HOH HOH A . 
E 3 HOH 76  476  346  HOH HOH A . 
E 3 HOH 77  477  256  HOH HOH A . 
E 3 HOH 78  478  412  HOH HOH A . 
E 3 HOH 79  479  562  HOH HOH A . 
E 3 HOH 80  480  156  HOH HOH A . 
E 3 HOH 81  481  75   HOH HOH A . 
E 3 HOH 82  482  106  HOH HOH A . 
E 3 HOH 83  483  484  HOH HOH A . 
E 3 HOH 84  484  814  HOH HOH A . 
E 3 HOH 85  485  107  HOH HOH A . 
E 3 HOH 86  486  648  HOH HOH A . 
E 3 HOH 87  487  121  HOH HOH A . 
E 3 HOH 88  488  446  HOH HOH A . 
E 3 HOH 89  489  1424 HOH HOH A . 
E 3 HOH 90  490  513  HOH HOH A . 
E 3 HOH 91  491  550  HOH HOH A . 
E 3 HOH 92  492  171  HOH HOH A . 
E 3 HOH 93  493  1322 HOH HOH A . 
E 3 HOH 94  494  563  HOH HOH A . 
E 3 HOH 95  495  1423 HOH HOH A . 
E 3 HOH 96  496  727  HOH HOH A . 
E 3 HOH 97  497  66   HOH HOH A . 
E 3 HOH 98  498  90   HOH HOH A . 
E 3 HOH 99  499  1038 HOH HOH A . 
E 3 HOH 100 500  494  HOH HOH A . 
E 3 HOH 101 501  246  HOH HOH A . 
E 3 HOH 102 502  219  HOH HOH A . 
E 3 HOH 103 503  282  HOH HOH A . 
E 3 HOH 104 504  72   HOH HOH A . 
E 3 HOH 105 505  198  HOH HOH A . 
E 3 HOH 106 506  126  HOH HOH A . 
E 3 HOH 107 507  18   HOH HOH A . 
E 3 HOH 108 508  784  HOH HOH A . 
E 3 HOH 109 509  22   HOH HOH A . 
E 3 HOH 110 510  306  HOH HOH A . 
E 3 HOH 111 511  28   HOH HOH A . 
E 3 HOH 112 512  1396 HOH HOH A . 
E 3 HOH 113 513  492  HOH HOH A . 
E 3 HOH 114 514  104  HOH HOH A . 
E 3 HOH 115 515  375  HOH HOH A . 
E 3 HOH 116 516  553  HOH HOH A . 
E 3 HOH 117 517  1250 HOH HOH A . 
E 3 HOH 118 518  739  HOH HOH A . 
E 3 HOH 119 519  528  HOH HOH A . 
E 3 HOH 120 520  552  HOH HOH A . 
E 3 HOH 121 521  369  HOH HOH A . 
E 3 HOH 122 522  447  HOH HOH A . 
E 3 HOH 123 523  393  HOH HOH A . 
E 3 HOH 124 524  174  HOH HOH A . 
E 3 HOH 125 525  636  HOH HOH A . 
E 3 HOH 126 526  37   HOH HOH A . 
E 3 HOH 127 527  20   HOH HOH A . 
E 3 HOH 128 528  1195 HOH HOH A . 
E 3 HOH 129 529  15   HOH HOH A . 
E 3 HOH 130 530  61   HOH HOH A . 
E 3 HOH 131 531  79   HOH HOH A . 
E 3 HOH 132 532  958  HOH HOH A . 
E 3 HOH 133 533  80   HOH HOH A . 
E 3 HOH 134 534  1168 HOH HOH A . 
E 3 HOH 135 535  350  HOH HOH A . 
E 3 HOH 136 536  694  HOH HOH A . 
E 3 HOH 137 537  119  HOH HOH A . 
E 3 HOH 138 538  576  HOH HOH A . 
E 3 HOH 139 539  1281 HOH HOH A . 
E 3 HOH 140 540  47   HOH HOH A . 
E 3 HOH 141 541  1324 HOH HOH A . 
E 3 HOH 142 542  771  HOH HOH A . 
E 3 HOH 143 543  281  HOH HOH A . 
E 3 HOH 144 544  108  HOH HOH A . 
E 3 HOH 145 545  826  HOH HOH A . 
E 3 HOH 146 546  455  HOH HOH A . 
E 3 HOH 147 547  857  HOH HOH A . 
E 3 HOH 148 548  777  HOH HOH A . 
E 3 HOH 149 549  147  HOH HOH A . 
E 3 HOH 150 550  1344 HOH HOH A . 
E 3 HOH 151 551  1012 HOH HOH A . 
E 3 HOH 152 552  24   HOH HOH A . 
E 3 HOH 153 553  359  HOH HOH A . 
E 3 HOH 154 554  776  HOH HOH A . 
E 3 HOH 155 555  704  HOH HOH A . 
E 3 HOH 156 556  97   HOH HOH A . 
E 3 HOH 157 557  245  HOH HOH A . 
E 3 HOH 158 558  876  HOH HOH A . 
E 3 HOH 159 559  82   HOH HOH A . 
E 3 HOH 160 560  83   HOH HOH A . 
E 3 HOH 161 561  415  HOH HOH A . 
E 3 HOH 162 562  1421 HOH HOH A . 
E 3 HOH 163 563  912  HOH HOH A . 
E 3 HOH 164 564  216  HOH HOH A . 
E 3 HOH 165 565  127  HOH HOH A . 
E 3 HOH 166 566  787  HOH HOH A . 
E 3 HOH 167 567  458  HOH HOH A . 
E 3 HOH 168 568  929  HOH HOH A . 
E 3 HOH 169 569  151  HOH HOH A . 
E 3 HOH 170 570  1060 HOH HOH A . 
E 3 HOH 171 571  443  HOH HOH A . 
E 3 HOH 172 572  138  HOH HOH A . 
E 3 HOH 173 573  21   HOH HOH A . 
E 3 HOH 174 574  228  HOH HOH A . 
E 3 HOH 175 575  489  HOH HOH A . 
E 3 HOH 176 576  570  HOH HOH A . 
E 3 HOH 177 577  280  HOH HOH A . 
E 3 HOH 178 578  915  HOH HOH A . 
E 3 HOH 179 579  203  HOH HOH A . 
E 3 HOH 180 580  315  HOH HOH A . 
E 3 HOH 181 581  40   HOH HOH A . 
E 3 HOH 182 582  262  HOH HOH A . 
E 3 HOH 183 583  137  HOH HOH A . 
E 3 HOH 184 584  365  HOH HOH A . 
E 3 HOH 185 585  115  HOH HOH A . 
E 3 HOH 186 586  665  HOH HOH A . 
E 3 HOH 187 587  11   HOH HOH A . 
E 3 HOH 188 588  817  HOH HOH A . 
E 3 HOH 189 589  36   HOH HOH A . 
E 3 HOH 190 590  62   HOH HOH A . 
E 3 HOH 191 591  12   HOH HOH A . 
E 3 HOH 192 592  391  HOH HOH A . 
E 3 HOH 193 593  19   HOH HOH A . 
E 3 HOH 194 594  205  HOH HOH A . 
E 3 HOH 195 595  150  HOH HOH A . 
E 3 HOH 196 596  230  HOH HOH A . 
E 3 HOH 197 597  140  HOH HOH A . 
E 3 HOH 198 598  1299 HOH HOH A . 
E 3 HOH 199 599  272  HOH HOH A . 
E 3 HOH 200 600  160  HOH HOH A . 
E 3 HOH 201 601  54   HOH HOH A . 
E 3 HOH 202 602  470  HOH HOH A . 
E 3 HOH 203 603  404  HOH HOH A . 
E 3 HOH 204 604  558  HOH HOH A . 
E 3 HOH 205 605  232  HOH HOH A . 
E 3 HOH 206 606  1058 HOH HOH A . 
E 3 HOH 207 607  1225 HOH HOH A . 
E 3 HOH 208 608  1318 HOH HOH A . 
E 3 HOH 209 609  811  HOH HOH A . 
E 3 HOH 210 610  526  HOH HOH A . 
E 3 HOH 211 611  187  HOH HOH A . 
E 3 HOH 212 612  249  HOH HOH A . 
E 3 HOH 213 613  92   HOH HOH A . 
E 3 HOH 214 614  409  HOH HOH A . 
E 3 HOH 215 615  101  HOH HOH A . 
E 3 HOH 216 616  1241 HOH HOH A . 
E 3 HOH 217 617  110  HOH HOH A . 
E 3 HOH 218 618  353  HOH HOH A . 
E 3 HOH 219 619  105  HOH HOH A . 
E 3 HOH 220 620  196  HOH HOH A . 
E 3 HOH 221 621  199  HOH HOH A . 
E 3 HOH 222 622  1397 HOH HOH A . 
E 3 HOH 223 623  920  HOH HOH A . 
E 3 HOH 224 624  1298 HOH HOH A . 
E 3 HOH 225 625  240  HOH HOH A . 
E 3 HOH 226 626  1162 HOH HOH A . 
E 3 HOH 227 627  173  HOH HOH A . 
E 3 HOH 228 628  863  HOH HOH A . 
E 3 HOH 229 629  560  HOH HOH A . 
E 3 HOH 230 630  746  HOH HOH A . 
E 3 HOH 231 631  290  HOH HOH A . 
E 3 HOH 232 632  729  HOH HOH A . 
E 3 HOH 233 633  278  HOH HOH A . 
E 3 HOH 234 634  57   HOH HOH A . 
E 3 HOH 235 635  93   HOH HOH A . 
E 3 HOH 236 636  55   HOH HOH A . 
E 3 HOH 237 637  846  HOH HOH A . 
E 3 HOH 238 638  158  HOH HOH A . 
E 3 HOH 239 639  250  HOH HOH A . 
E 3 HOH 240 640  1257 HOH HOH A . 
E 3 HOH 241 641  899  HOH HOH A . 
E 3 HOH 242 642  832  HOH HOH A . 
E 3 HOH 243 643  224  HOH HOH A . 
E 3 HOH 244 644  1169 HOH HOH A . 
E 3 HOH 245 645  242  HOH HOH A . 
E 3 HOH 246 646  1065 HOH HOH A . 
E 3 HOH 247 647  84   HOH HOH A . 
E 3 HOH 248 648  313  HOH HOH A . 
E 3 HOH 249 649  913  HOH HOH A . 
E 3 HOH 250 650  853  HOH HOH A . 
E 3 HOH 251 651  255  HOH HOH A . 
E 3 HOH 252 652  794  HOH HOH A . 
E 3 HOH 253 653  258  HOH HOH A . 
E 3 HOH 254 654  1083 HOH HOH A . 
E 3 HOH 255 655  1267 HOH HOH A . 
E 3 HOH 256 656  972  HOH HOH A . 
E 3 HOH 257 657  908  HOH HOH A . 
E 3 HOH 258 658  352  HOH HOH A . 
E 3 HOH 259 659  301  HOH HOH A . 
E 3 HOH 260 660  233  HOH HOH A . 
E 3 HOH 261 661  522  HOH HOH A . 
E 3 HOH 262 662  477  HOH HOH A . 
E 3 HOH 263 663  629  HOH HOH A . 
E 3 HOH 264 664  880  HOH HOH A . 
E 3 HOH 265 665  52   HOH HOH A . 
E 3 HOH 266 666  909  HOH HOH A . 
E 3 HOH 267 667  434  HOH HOH A . 
E 3 HOH 268 668  970  HOH HOH A . 
E 3 HOH 269 669  23   HOH HOH A . 
E 3 HOH 270 670  543  HOH HOH A . 
E 3 HOH 271 671  178  HOH HOH A . 
E 3 HOH 272 672  637  HOH HOH A . 
E 3 HOH 273 673  410  HOH HOH A . 
E 3 HOH 274 674  1368 HOH HOH A . 
E 3 HOH 275 675  1062 HOH HOH A . 
E 3 HOH 276 676  53   HOH HOH A . 
E 3 HOH 277 677  1336 HOH HOH A . 
E 3 HOH 278 678  1034 HOH HOH A . 
E 3 HOH 279 679  142  HOH HOH A . 
E 3 HOH 280 680  322  HOH HOH A . 
E 3 HOH 281 681  942  HOH HOH A . 
E 3 HOH 282 682  660  HOH HOH A . 
E 3 HOH 283 683  25   HOH HOH A . 
E 3 HOH 284 684  547  HOH HOH A . 
E 3 HOH 285 685  567  HOH HOH A . 
E 3 HOH 286 686  749  HOH HOH A . 
E 3 HOH 287 687  385  HOH HOH A . 
E 3 HOH 288 688  1015 HOH HOH A . 
E 3 HOH 289 689  408  HOH HOH A . 
E 3 HOH 290 690  453  HOH HOH A . 
E 3 HOH 291 691  1307 HOH HOH A . 
E 3 HOH 292 692  1004 HOH HOH A . 
E 3 HOH 293 693  1273 HOH HOH A . 
E 3 HOH 294 694  268  HOH HOH A . 
E 3 HOH 295 695  444  HOH HOH A . 
E 3 HOH 296 696  1098 HOH HOH A . 
E 3 HOH 297 697  98   HOH HOH A . 
E 3 HOH 298 698  273  HOH HOH A . 
E 3 HOH 299 699  468  HOH HOH A . 
E 3 HOH 300 700  580  HOH HOH A . 
E 3 HOH 301 701  210  HOH HOH A . 
E 3 HOH 302 702  600  HOH HOH A . 
E 3 HOH 303 703  1121 HOH HOH A . 
E 3 HOH 304 704  742  HOH HOH A . 
E 3 HOH 305 705  609  HOH HOH A . 
E 3 HOH 306 706  56   HOH HOH A . 
E 3 HOH 307 707  68   HOH HOH A . 
E 3 HOH 308 708  1416 HOH HOH A . 
E 3 HOH 309 709  601  HOH HOH A . 
E 3 HOH 310 710  564  HOH HOH A . 
E 3 HOH 311 711  508  HOH HOH A . 
E 3 HOH 312 712  933  HOH HOH A . 
E 3 HOH 313 713  498  HOH HOH A . 
E 3 HOH 314 714  680  HOH HOH A . 
E 3 HOH 315 715  631  HOH HOH A . 
E 3 HOH 316 716  668  HOH HOH A . 
E 3 HOH 317 717  1301 HOH HOH A . 
E 3 HOH 318 718  604  HOH HOH A . 
E 3 HOH 319 719  251  HOH HOH A . 
E 3 HOH 320 720  506  HOH HOH A . 
E 3 HOH 321 721  367  HOH HOH A . 
E 3 HOH 322 722  780  HOH HOH A . 
E 3 HOH 323 723  687  HOH HOH A . 
E 3 HOH 324 724  180  HOH HOH A . 
E 3 HOH 325 725  722  HOH HOH A . 
E 3 HOH 326 726  1334 HOH HOH A . 
E 3 HOH 327 727  758  HOH HOH A . 
E 3 HOH 328 728  433  HOH HOH A . 
E 3 HOH 329 729  577  HOH HOH A . 
E 3 HOH 330 730  1402 HOH HOH A . 
E 3 HOH 331 731  1316 HOH HOH A . 
E 3 HOH 332 732  1329 HOH HOH A . 
E 3 HOH 333 733  134  HOH HOH A . 
E 3 HOH 334 734  1239 HOH HOH A . 
E 3 HOH 335 735  1405 HOH HOH A . 
E 3 HOH 336 736  451  HOH HOH A . 
E 3 HOH 337 737  559  HOH HOH A . 
E 3 HOH 338 738  592  HOH HOH A . 
E 3 HOH 339 739  841  HOH HOH A . 
E 3 HOH 340 740  1280 HOH HOH A . 
E 3 HOH 341 741  440  HOH HOH A . 
E 3 HOH 342 742  877  HOH HOH A . 
E 3 HOH 343 743  27   HOH HOH A . 
E 3 HOH 344 744  778  HOH HOH A . 
E 3 HOH 345 745  1159 HOH HOH A . 
E 3 HOH 346 746  935  HOH HOH A . 
E 3 HOH 347 747  77   HOH HOH A . 
E 3 HOH 348 748  536  HOH HOH A . 
E 3 HOH 349 749  1055 HOH HOH A . 
E 3 HOH 350 750  527  HOH HOH A . 
E 3 HOH 351 751  438  HOH HOH A . 
E 3 HOH 352 752  1157 HOH HOH A . 
E 3 HOH 353 753  617  HOH HOH A . 
E 3 HOH 354 754  1125 HOH HOH A . 
E 3 HOH 355 755  384  HOH HOH A . 
E 3 HOH 356 756  1186 HOH HOH A . 
E 3 HOH 357 757  1362 HOH HOH A . 
E 3 HOH 358 758  1293 HOH HOH A . 
E 3 HOH 359 759  435  HOH HOH A . 
E 3 HOH 360 760  622  HOH HOH A . 
E 3 HOH 361 761  1395 HOH HOH A . 
E 3 HOH 362 762  102  HOH HOH A . 
E 3 HOH 363 763  432  HOH HOH A . 
E 3 HOH 364 764  260  HOH HOH A . 
E 3 HOH 365 765  611  HOH HOH A . 
E 3 HOH 366 766  566  HOH HOH A . 
E 3 HOH 367 767  60   HOH HOH A . 
E 3 HOH 368 768  488  HOH HOH A . 
E 3 HOH 369 769  892  HOH HOH A . 
E 3 HOH 370 770  797  HOH HOH A . 
E 3 HOH 371 771  495  HOH HOH A . 
E 3 HOH 372 772  545  HOH HOH A . 
E 3 HOH 373 773  1110 HOH HOH A . 
E 3 HOH 374 774  544  HOH HOH A . 
E 3 HOH 375 775  868  HOH HOH A . 
E 3 HOH 376 776  793  HOH HOH A . 
E 3 HOH 377 777  197  HOH HOH A . 
E 3 HOH 378 778  1268 HOH HOH A . 
E 3 HOH 379 779  122  HOH HOH A . 
E 3 HOH 380 780  839  HOH HOH A . 
E 3 HOH 381 781  1302 HOH HOH A . 
E 3 HOH 382 782  904  HOH HOH A . 
E 3 HOH 383 783  426  HOH HOH A . 
E 3 HOH 384 784  368  HOH HOH A . 
E 3 HOH 385 785  1415 HOH HOH A . 
E 3 HOH 386 786  1166 HOH HOH A . 
E 3 HOH 387 787  496  HOH HOH A . 
E 3 HOH 388 788  1000 HOH HOH A . 
E 3 HOH 389 789  638  HOH HOH A . 
E 3 HOH 390 790  356  HOH HOH A . 
E 3 HOH 391 791  521  HOH HOH A . 
E 3 HOH 392 792  986  HOH HOH A . 
E 3 HOH 393 793  1263 HOH HOH A . 
E 3 HOH 394 794  99   HOH HOH A . 
E 3 HOH 395 795  504  HOH HOH A . 
E 3 HOH 396 796  711  HOH HOH A . 
E 3 HOH 397 797  910  HOH HOH A . 
E 3 HOH 398 798  819  HOH HOH A . 
E 3 HOH 399 799  555  HOH HOH A . 
E 3 HOH 400 800  74   HOH HOH A . 
E 3 HOH 401 801  387  HOH HOH A . 
E 3 HOH 402 802  329  HOH HOH A . 
E 3 HOH 403 803  161  HOH HOH A . 
E 3 HOH 404 804  542  HOH HOH A . 
E 3 HOH 405 805  261  HOH HOH A . 
E 3 HOH 406 806  190  HOH HOH A . 
E 3 HOH 407 807  900  HOH HOH A . 
E 3 HOH 408 808  761  HOH HOH A . 
E 3 HOH 409 809  417  HOH HOH A . 
E 3 HOH 410 810  671  HOH HOH A . 
E 3 HOH 411 811  745  HOH HOH A . 
E 3 HOH 412 812  1360 HOH HOH A . 
E 3 HOH 413 813  842  HOH HOH A . 
E 3 HOH 414 814  421  HOH HOH A . 
E 3 HOH 415 815  184  HOH HOH A . 
E 3 HOH 416 816  788  HOH HOH A . 
E 3 HOH 417 817  840  HOH HOH A . 
E 3 HOH 418 818  967  HOH HOH A . 
E 3 HOH 419 819  1277 HOH HOH A . 
E 3 HOH 420 820  1203 HOH HOH A . 
E 3 HOH 421 821  1230 HOH HOH A . 
E 3 HOH 422 822  961  HOH HOH A . 
E 3 HOH 423 823  926  HOH HOH A . 
E 3 HOH 424 824  1237 HOH HOH A . 
E 3 HOH 425 825  239  HOH HOH A . 
E 3 HOH 426 826  1313 HOH HOH A . 
E 3 HOH 427 827  229  HOH HOH A . 
E 3 HOH 428 828  377  HOH HOH A . 
E 3 HOH 429 829  1319 HOH HOH A . 
E 3 HOH 430 830  406  HOH HOH A . 
E 3 HOH 431 831  884  HOH HOH A . 
E 3 HOH 432 832  1366 HOH HOH A . 
E 3 HOH 433 833  1016 HOH HOH A . 
E 3 HOH 434 834  1403 HOH HOH A . 
E 3 HOH 435 835  1144 HOH HOH A . 
E 3 HOH 436 836  1414 HOH HOH A . 
E 3 HOH 437 837  1227 HOH HOH A . 
E 3 HOH 438 838  956  HOH HOH A . 
E 3 HOH 439 839  146  HOH HOH A . 
E 3 HOH 440 840  1048 HOH HOH A . 
E 3 HOH 441 841  1045 HOH HOH A . 
E 3 HOH 442 842  1191 HOH HOH A . 
E 3 HOH 443 843  1020 HOH HOH A . 
E 3 HOH 444 844  1411 HOH HOH A . 
E 3 HOH 445 845  1120 HOH HOH A . 
E 3 HOH 446 846  1215 HOH HOH A . 
E 3 HOH 447 847  1103 HOH HOH A . 
E 3 HOH 448 848  370  HOH HOH A . 
E 3 HOH 449 849  1222 HOH HOH A . 
E 3 HOH 450 850  1036 HOH HOH A . 
E 3 HOH 451 851  714  HOH HOH A . 
E 3 HOH 452 852  911  HOH HOH A . 
E 3 HOH 453 853  769  HOH HOH A . 
E 3 HOH 454 854  801  HOH HOH A . 
E 3 HOH 455 855  922  HOH HOH A . 
E 3 HOH 456 856  965  HOH HOH A . 
E 3 HOH 457 857  651  HOH HOH A . 
E 3 HOH 458 858  485  HOH HOH A . 
E 3 HOH 459 859  572  HOH HOH A . 
E 3 HOH 460 860  1306 HOH HOH A . 
E 3 HOH 461 861  901  HOH HOH A . 
E 3 HOH 462 862  1181 HOH HOH A . 
E 3 HOH 463 863  1205 HOH HOH A . 
E 3 HOH 464 864  482  HOH HOH A . 
E 3 HOH 465 865  1202 HOH HOH A . 
E 3 HOH 466 866  319  HOH HOH A . 
E 3 HOH 467 867  992  HOH HOH A . 
E 3 HOH 468 868  535  HOH HOH A . 
E 3 HOH 469 869  1376 HOH HOH A . 
E 3 HOH 470 870  1212 HOH HOH A . 
E 3 HOH 471 871  100  HOH HOH A . 
E 3 HOH 472 872  700  HOH HOH A . 
E 3 HOH 473 873  1350 HOH HOH A . 
E 3 HOH 474 874  951  HOH HOH A . 
E 3 HOH 475 875  1308 HOH HOH A . 
E 3 HOH 476 876  574  HOH HOH A . 
E 3 HOH 477 877  1029 HOH HOH A . 
E 3 HOH 478 878  642  HOH HOH A . 
E 3 HOH 479 879  1116 HOH HOH A . 
E 3 HOH 480 880  980  HOH HOH A . 
E 3 HOH 481 881  507  HOH HOH A . 
E 3 HOH 482 882  997  HOH HOH A . 
E 3 HOH 483 883  881  HOH HOH A . 
E 3 HOH 484 884  1066 HOH HOH A . 
E 3 HOH 485 885  921  HOH HOH A . 
E 3 HOH 486 886  418  HOH HOH A . 
E 3 HOH 487 887  1077 HOH HOH A . 
E 3 HOH 488 888  1226 HOH HOH A . 
E 3 HOH 489 889  802  HOH HOH A . 
E 3 HOH 490 890  208  HOH HOH A . 
E 3 HOH 491 891  154  HOH HOH A . 
E 3 HOH 492 892  1323 HOH HOH A . 
E 3 HOH 493 893  903  HOH HOH A . 
E 3 HOH 494 894  225  HOH HOH A . 
E 3 HOH 495 895  705  HOH HOH A . 
E 3 HOH 496 896  1406 HOH HOH A . 
E 3 HOH 497 897  303  HOH HOH A . 
E 3 HOH 498 898  702  HOH HOH A . 
E 3 HOH 499 899  360  HOH HOH A . 
E 3 HOH 500 900  1342 HOH HOH A . 
E 3 HOH 501 901  217  HOH HOH A . 
E 3 HOH 502 902  1142 HOH HOH A . 
E 3 HOH 503 903  413  HOH HOH A . 
E 3 HOH 504 904  1238 HOH HOH A . 
E 3 HOH 505 905  807  HOH HOH A . 
E 3 HOH 506 906  1156 HOH HOH A . 
E 3 HOH 507 907  981  HOH HOH A . 
E 3 HOH 508 908  1331 HOH HOH A . 
E 3 HOH 509 909  1152 HOH HOH A . 
E 3 HOH 510 910  222  HOH HOH A . 
E 3 HOH 511 911  860  HOH HOH A . 
E 3 HOH 512 912  1235 HOH HOH A . 
E 3 HOH 513 913  747  HOH HOH A . 
E 3 HOH 514 914  605  HOH HOH A . 
E 3 HOH 515 915  499  HOH HOH A . 
E 3 HOH 516 916  737  HOH HOH A . 
E 3 HOH 517 917  1109 HOH HOH A . 
E 3 HOH 518 918  263  HOH HOH A . 
E 3 HOH 519 919  627  HOH HOH A . 
E 3 HOH 520 920  1154 HOH HOH A . 
E 3 HOH 521 921  1294 HOH HOH A . 
E 3 HOH 522 922  1067 HOH HOH A . 
E 3 HOH 523 923  640  HOH HOH A . 
E 3 HOH 524 924  170  HOH HOH A . 
E 3 HOH 525 925  1179 HOH HOH A . 
E 3 HOH 526 926  1136 HOH HOH A . 
E 3 HOH 527 927  941  HOH HOH A . 
E 3 HOH 528 928  1188 HOH HOH A . 
E 3 HOH 529 929  982  HOH HOH A . 
E 3 HOH 530 930  789  HOH HOH A . 
E 3 HOH 531 931  655  HOH HOH A . 
E 3 HOH 532 932  667  HOH HOH A . 
E 3 HOH 533 933  633  HOH HOH A . 
E 3 HOH 534 934  318  HOH HOH A . 
E 3 HOH 535 935  1001 HOH HOH A . 
E 3 HOH 536 936  657  HOH HOH A . 
E 3 HOH 537 937  1275 HOH HOH A . 
E 3 HOH 538 938  1261 HOH HOH A . 
E 3 HOH 539 939  1113 HOH HOH A . 
E 3 HOH 540 940  266  HOH HOH A . 
E 3 HOH 541 941  537  HOH HOH A . 
E 3 HOH 542 942  111  HOH HOH A . 
E 3 HOH 543 943  309  HOH HOH A . 
E 3 HOH 544 944  348  HOH HOH A . 
E 3 HOH 545 945  1174 HOH HOH A . 
E 3 HOH 546 946  683  HOH HOH A . 
E 3 HOH 547 947  1249 HOH HOH A . 
E 3 HOH 548 948  1303 HOH HOH A . 
E 3 HOH 549 949  238  HOH HOH A . 
E 3 HOH 550 950  1390 HOH HOH A . 
E 3 HOH 551 951  1210 HOH HOH A . 
E 3 HOH 552 952  743  HOH HOH A . 
E 3 HOH 553 953  887  HOH HOH A . 
E 3 HOH 554 954  1127 HOH HOH A . 
E 3 HOH 555 955  1151 HOH HOH A . 
E 3 HOH 556 956  1164 HOH HOH A . 
E 3 HOH 557 957  465  HOH HOH A . 
E 3 HOH 558 958  589  HOH HOH A . 
E 3 HOH 559 959  139  HOH HOH A . 
E 3 HOH 560 960  1057 HOH HOH A . 
E 3 HOH 561 961  420  HOH HOH A . 
E 3 HOH 562 962  1289 HOH HOH A . 
E 3 HOH 563 963  764  HOH HOH A . 
E 3 HOH 564 964  1422 HOH HOH A . 
E 3 HOH 565 965  1375 HOH HOH A . 
E 3 HOH 566 966  207  HOH HOH A . 
E 3 HOH 567 967  575  HOH HOH A . 
E 3 HOH 568 968  927  HOH HOH A . 
E 3 HOH 569 969  302  HOH HOH A . 
E 3 HOH 570 970  532  HOH HOH A . 
E 3 HOH 571 971  1049 HOH HOH A . 
E 3 HOH 572 972  750  HOH HOH A . 
E 3 HOH 573 973  800  HOH HOH A . 
E 3 HOH 574 974  472  HOH HOH A . 
E 3 HOH 575 975  1189 HOH HOH A . 
E 3 HOH 576 976  1118 HOH HOH A . 
E 3 HOH 577 977  808  HOH HOH A . 
E 3 HOH 578 978  1385 HOH HOH A . 
E 3 HOH 579 979  898  HOH HOH A . 
E 3 HOH 580 980  932  HOH HOH A . 
E 3 HOH 581 981  1059 HOH HOH A . 
E 3 HOH 582 982  1347 HOH HOH A . 
E 3 HOH 583 983  1343 HOH HOH A . 
E 3 HOH 584 984  584  HOH HOH A . 
E 3 HOH 585 985  231  HOH HOH A . 
E 3 HOH 586 986  1129 HOH HOH A . 
E 3 HOH 587 987  791  HOH HOH A . 
E 3 HOH 588 988  782  HOH HOH A . 
E 3 HOH 589 989  735  HOH HOH A . 
E 3 HOH 590 990  1005 HOH HOH A . 
E 3 HOH 591 991  707  HOH HOH A . 
E 3 HOH 592 992  623  HOH HOH A . 
E 3 HOH 593 993  585  HOH HOH A . 
E 3 HOH 594 994  775  HOH HOH A . 
E 3 HOH 595 995  862  HOH HOH A . 
E 3 HOH 596 996  818  HOH HOH A . 
E 3 HOH 597 997  557  HOH HOH A . 
E 3 HOH 598 998  767  HOH HOH A . 
E 3 HOH 599 999  998  HOH HOH A . 
E 3 HOH 600 1000 1211 HOH HOH A . 
E 3 HOH 601 1001 1217 HOH HOH A . 
E 3 HOH 602 1002 1177 HOH HOH A . 
E 3 HOH 603 1003 830  HOH HOH A . 
E 3 HOH 604 1004 511  HOH HOH A . 
E 3 HOH 605 1005 1407 HOH HOH A . 
E 3 HOH 606 1006 1183 HOH HOH A . 
E 3 HOH 607 1007 1185 HOH HOH A . 
E 3 HOH 608 1008 1013 HOH HOH A . 
E 3 HOH 609 1009 1153 HOH HOH A . 
E 3 HOH 610 1010 804  HOH HOH A . 
E 3 HOH 611 1011 716  HOH HOH A . 
E 3 HOH 612 1012 1071 HOH HOH A . 
E 3 HOH 613 1013 1140 HOH HOH A . 
E 3 HOH 614 1014 781  HOH HOH A . 
E 3 HOH 615 1015 755  HOH HOH A . 
E 3 HOH 616 1016 561  HOH HOH A . 
E 3 HOH 617 1017 849  HOH HOH A . 
E 3 HOH 618 1018 1072 HOH HOH A . 
E 3 HOH 619 1019 1182 HOH HOH A . 
E 3 HOH 620 1020 1030 HOH HOH A . 
E 3 HOH 621 1021 565  HOH HOH A . 
E 3 HOH 622 1022 624  HOH HOH A . 
E 3 HOH 623 1023 530  HOH HOH A . 
E 3 HOH 624 1024 1075 HOH HOH A . 
E 3 HOH 625 1025 1014 HOH HOH A . 
E 3 HOH 626 1026 1132 HOH HOH A . 
E 3 HOH 627 1027 613  HOH HOH A . 
E 3 HOH 628 1028 1311 HOH HOH A . 
E 3 HOH 629 1029 1359 HOH HOH A . 
E 3 HOH 630 1030 411  HOH HOH A . 
E 3 HOH 631 1031 1300 HOH HOH A . 
E 3 HOH 632 1032 689  HOH HOH A . 
E 3 HOH 633 1033 1149 HOH HOH A . 
E 3 HOH 634 1034 252  HOH HOH A . 
E 3 HOH 635 1035 659  HOH HOH A . 
E 3 HOH 636 1036 1353 HOH HOH A . 
E 3 HOH 637 1037 1137 HOH HOH A . 
E 3 HOH 638 1038 509  HOH HOH A . 
E 3 HOH 639 1039 850  HOH HOH A . 
E 3 HOH 640 1040 752  HOH HOH A . 
E 3 HOH 641 1041 1024 HOH HOH A . 
E 3 HOH 642 1042 483  HOH HOH A . 
E 3 HOH 643 1043 596  HOH HOH A . 
E 3 HOH 644 1044 474  HOH HOH A . 
E 3 HOH 645 1045 888  HOH HOH A . 
E 3 HOH 646 1046 339  HOH HOH A . 
E 3 HOH 647 1047 1021 HOH HOH A . 
E 3 HOH 648 1048 682  HOH HOH A . 
E 3 HOH 649 1049 999  HOH HOH A . 
E 3 HOH 650 1050 1112 HOH HOH A . 
E 3 HOH 651 1051 265  HOH HOH A . 
E 3 HOH 652 1052 361  HOH HOH A . 
E 3 HOH 653 1053 669  HOH HOH A . 
E 3 HOH 654 1054 856  HOH HOH A . 
E 3 HOH 655 1055 582  HOH HOH A . 
E 3 HOH 656 1056 966  HOH HOH A . 
E 3 HOH 657 1057 347  HOH HOH A . 
E 3 HOH 658 1058 1155 HOH HOH A . 
E 3 HOH 659 1059 546  HOH HOH A . 
E 3 HOH 660 1060 503  HOH HOH A . 
E 3 HOH 661 1061 1138 HOH HOH A . 
E 3 HOH 662 1062 1134 HOH HOH A . 
E 3 HOH 663 1063 974  HOH HOH A . 
E 3 HOH 664 1064 120  HOH HOH A . 
E 3 HOH 665 1065 342  HOH HOH A . 
E 3 HOH 666 1066 1264 HOH HOH A . 
E 3 HOH 667 1067 1002 HOH HOH A . 
E 3 HOH 668 1068 1285 HOH HOH A . 
E 3 HOH 669 1069 730  HOH HOH A . 
E 3 HOH 670 1070 1145 HOH HOH A . 
E 3 HOH 671 1071 452  HOH HOH A . 
E 3 HOH 672 1072 1184 HOH HOH A . 
E 3 HOH 673 1073 405  HOH HOH A . 
E 3 HOH 674 1074 76   HOH HOH A . 
E 3 HOH 675 1075 625  HOH HOH A . 
E 3 HOH 676 1076 372  HOH HOH A . 
E 3 HOH 677 1077 1173 HOH HOH A . 
E 3 HOH 678 1078 1358 HOH HOH A . 
E 3 HOH 679 1079 799  HOH HOH A . 
E 3 HOH 680 1080 478  HOH HOH A . 
E 3 HOH 681 1081 153  HOH HOH A . 
E 3 HOH 682 1082 661  HOH HOH A . 
E 3 HOH 683 1083 612  HOH HOH A . 
E 3 HOH 684 1084 534  HOH HOH A . 
E 3 HOH 685 1085 1035 HOH HOH A . 
E 3 HOH 686 1086 1095 HOH HOH A . 
E 3 HOH 687 1087 1380 HOH HOH A . 
E 3 HOH 688 1088 692  HOH HOH A . 
E 3 HOH 689 1089 1297 HOH HOH A . 
E 3 HOH 690 1090 583  HOH HOH A . 
E 3 HOH 691 1091 1206 HOH HOH A . 
E 3 HOH 692 1092 1033 HOH HOH A . 
E 3 HOH 693 1093 383  HOH HOH A . 
E 3 HOH 694 1094 457  HOH HOH A . 
E 3 HOH 695 1095 852  HOH HOH A . 
F 3 HOH 1   401  1023 HOH HOH B . 
F 3 HOH 2   402  616  HOH HOH B . 
F 3 HOH 3   403  1295 HOH HOH B . 
F 3 HOH 4   404  1314 HOH HOH B . 
F 3 HOH 5   405  1271 HOH HOH B . 
F 3 HOH 6   406  2    HOH HOH B . 
F 3 HOH 7   407  1340 HOH HOH B . 
F 3 HOH 8   408  760  HOH HOH B . 
F 3 HOH 9   409  1192 HOH HOH B . 
F 3 HOH 10  410  1278 HOH HOH B . 
F 3 HOH 11  411  214  HOH HOH B . 
F 3 HOH 12  412  1279 HOH HOH B . 
F 3 HOH 13  413  1054 HOH HOH B . 
F 3 HOH 14  414  825  HOH HOH B . 
F 3 HOH 15  415  1346 HOH HOH B . 
F 3 HOH 16  416  1019 HOH HOH B . 
F 3 HOH 17  417  460  HOH HOH B . 
F 3 HOH 18  418  795  HOH HOH B . 
F 3 HOH 19  419  757  HOH HOH B . 
F 3 HOH 20  420  1193 HOH HOH B . 
F 3 HOH 21  421  487  HOH HOH B . 
F 3 HOH 22  422  467  HOH HOH B . 
F 3 HOH 23  423  597  HOH HOH B . 
F 3 HOH 24  424  1266 HOH HOH B . 
F 3 HOH 25  425  654  HOH HOH B . 
F 3 HOH 26  426  732  HOH HOH B . 
F 3 HOH 27  427  1063 HOH HOH B . 
F 3 HOH 28  428  1041 HOH HOH B . 
F 3 HOH 29  429  1010 HOH HOH B . 
F 3 HOH 30  430  595  HOH HOH B . 
F 3 HOH 31  431  907  HOH HOH B . 
F 3 HOH 32  432  897  HOH HOH B . 
F 3 HOH 33  433  14   HOH HOH B . 
F 3 HOH 34  434  253  HOH HOH B . 
F 3 HOH 35  435  816  HOH HOH B . 
F 3 HOH 36  436  1076 HOH HOH B . 
F 3 HOH 37  437  969  HOH HOH B . 
F 3 HOH 38  438  573  HOH HOH B . 
F 3 HOH 39  439  364  HOH HOH B . 
F 3 HOH 40  440  267  HOH HOH B . 
F 3 HOH 41  441  1009 HOH HOH B . 
F 3 HOH 42  442  645  HOH HOH B . 
F 3 HOH 43  443  373  HOH HOH B . 
F 3 HOH 44  444  1417 HOH HOH B . 
F 3 HOH 45  445  397  HOH HOH B . 
F 3 HOH 46  446  34   HOH HOH B . 
F 3 HOH 47  447  679  HOH HOH B . 
F 3 HOH 48  448  304  HOH HOH B . 
F 3 HOH 49  449  524  HOH HOH B . 
F 3 HOH 50  450  740  HOH HOH B . 
F 3 HOH 51  451  878  HOH HOH B . 
F 3 HOH 52  452  317  HOH HOH B . 
F 3 HOH 53  453  848  HOH HOH B . 
F 3 HOH 54  454  493  HOH HOH B . 
F 3 HOH 55  455  165  HOH HOH B . 
F 3 HOH 56  456  812  HOH HOH B . 
F 3 HOH 57  457  1317 HOH HOH B . 
F 3 HOH 58  458  1085 HOH HOH B . 
F 3 HOH 59  459  674  HOH HOH B . 
F 3 HOH 60  460  112  HOH HOH B . 
F 3 HOH 61  461  386  HOH HOH B . 
F 3 HOH 62  462  1221 HOH HOH B . 
F 3 HOH 63  463  479  HOH HOH B . 
F 3 HOH 64  464  123  HOH HOH B . 
F 3 HOH 65  465  471  HOH HOH B . 
F 3 HOH 66  466  1043 HOH HOH B . 
F 3 HOH 67  467  531  HOH HOH B . 
F 3 HOH 68  468  641  HOH HOH B . 
F 3 HOH 69  469  957  HOH HOH B . 
F 3 HOH 70  470  456  HOH HOH B . 
F 3 HOH 71  471  128  HOH HOH B . 
F 3 HOH 72  472  1105 HOH HOH B . 
F 3 HOH 73  473  882  HOH HOH B . 
F 3 HOH 74  474  78   HOH HOH B . 
F 3 HOH 75  475  254  HOH HOH B . 
F 3 HOH 76  476  70   HOH HOH B . 
F 3 HOH 77  477  626  HOH HOH B . 
F 3 HOH 78  478  39   HOH HOH B . 
F 3 HOH 79  479  168  HOH HOH B . 
F 3 HOH 80  480  630  HOH HOH B . 
F 3 HOH 81  481  248  HOH HOH B . 
F 3 HOH 82  482  259  HOH HOH B . 
F 3 HOH 83  483  733  HOH HOH B . 
F 3 HOH 84  484  539  HOH HOH B . 
F 3 HOH 85  485  514  HOH HOH B . 
F 3 HOH 86  486  45   HOH HOH B . 
F 3 HOH 87  487  71   HOH HOH B . 
F 3 HOH 88  488  1037 HOH HOH B . 
F 3 HOH 89  489  94   HOH HOH B . 
F 3 HOH 90  490  1228 HOH HOH B . 
F 3 HOH 91  491  510  HOH HOH B . 
F 3 HOH 92  492  517  HOH HOH B . 
F 3 HOH 93  493  149  HOH HOH B . 
F 3 HOH 94  494  407  HOH HOH B . 
F 3 HOH 95  495  628  HOH HOH B . 
F 3 HOH 96  496  354  HOH HOH B . 
F 3 HOH 97  497  431  HOH HOH B . 
F 3 HOH 98  498  63   HOH HOH B . 
F 3 HOH 99  499  424  HOH HOH B . 
F 3 HOH 100 500  335  HOH HOH B . 
F 3 HOH 101 501  675  HOH HOH B . 
F 3 HOH 102 502  305  HOH HOH B . 
F 3 HOH 103 503  422  HOH HOH B . 
F 3 HOH 104 504  937  HOH HOH B . 
F 3 HOH 105 505  6    HOH HOH B . 
F 3 HOH 106 506  703  HOH HOH B . 
F 3 HOH 107 507  30   HOH HOH B . 
F 3 HOH 108 508  152  HOH HOH B . 
F 3 HOH 109 509  382  HOH HOH B . 
F 3 HOH 110 510  144  HOH HOH B . 
F 3 HOH 111 511  569  HOH HOH B . 
F 3 HOH 112 512  131  HOH HOH B . 
F 3 HOH 113 513  351  HOH HOH B . 
F 3 HOH 114 514  324  HOH HOH B . 
F 3 HOH 115 515  833  HOH HOH B . 
F 3 HOH 116 516  343  HOH HOH B . 
F 3 HOH 117 517  237  HOH HOH B . 
F 3 HOH 118 518  928  HOH HOH B . 
F 3 HOH 119 519  223  HOH HOH B . 
F 3 HOH 120 520  475  HOH HOH B . 
F 3 HOH 121 521  515  HOH HOH B . 
F 3 HOH 122 522  201  HOH HOH B . 
F 3 HOH 123 523  607  HOH HOH B . 
F 3 HOH 124 524  41   HOH HOH B . 
F 3 HOH 125 525  423  HOH HOH B . 
F 3 HOH 126 526  91   HOH HOH B . 
F 3 HOH 127 527  191  HOH HOH B . 
F 3 HOH 128 528  1251 HOH HOH B . 
F 3 HOH 129 529  188  HOH HOH B . 
F 3 HOH 130 530  950  HOH HOH B . 
F 3 HOH 131 531  67   HOH HOH B . 
F 3 HOH 132 532  288  HOH HOH B . 
F 3 HOH 133 533  1088 HOH HOH B . 
F 3 HOH 134 534  114  HOH HOH B . 
F 3 HOH 135 535  141  HOH HOH B . 
F 3 HOH 136 536  287  HOH HOH B . 
F 3 HOH 137 537  1108 HOH HOH B . 
F 3 HOH 138 538  618  HOH HOH B . 
F 3 HOH 139 539  16   HOH HOH B . 
F 3 HOH 140 540  1404 HOH HOH B . 
F 3 HOH 141 541  274  HOH HOH B . 
F 3 HOH 142 542  469  HOH HOH B . 
F 3 HOH 143 543  182  HOH HOH B . 
F 3 HOH 144 544  179  HOH HOH B . 
F 3 HOH 145 545  697  HOH HOH B . 
F 3 HOH 146 546  48   HOH HOH B . 
F 3 HOH 147 547  653  HOH HOH B . 
F 3 HOH 148 548  292  HOH HOH B . 
F 3 HOH 149 549  86   HOH HOH B . 
F 3 HOH 150 550  923  HOH HOH B . 
F 3 HOH 151 551  116  HOH HOH B . 
F 3 HOH 152 552  454  HOH HOH B . 
F 3 HOH 153 553  1146 HOH HOH B . 
F 3 HOH 154 554  81   HOH HOH B . 
F 3 HOH 155 555  652  HOH HOH B . 
F 3 HOH 156 556  243  HOH HOH B . 
F 3 HOH 157 557  186  HOH HOH B . 
F 3 HOH 158 558  1018 HOH HOH B . 
F 3 HOH 159 559  166  HOH HOH B . 
F 3 HOH 160 560  183  HOH HOH B . 
F 3 HOH 161 561  26   HOH HOH B . 
F 3 HOH 162 562  334  HOH HOH B . 
F 3 HOH 163 563  13   HOH HOH B . 
F 3 HOH 164 564  193  HOH HOH B . 
F 3 HOH 165 565  130  HOH HOH B . 
F 3 HOH 166 566  658  HOH HOH B . 
F 3 HOH 167 567  389  HOH HOH B . 
F 3 HOH 168 568  293  HOH HOH B . 
F 3 HOH 169 569  338  HOH HOH B . 
F 3 HOH 170 570  779  HOH HOH B . 
F 3 HOH 171 571  145  HOH HOH B . 
F 3 HOH 172 572  1320 HOH HOH B . 
F 3 HOH 173 573  1124 HOH HOH B . 
F 3 HOH 174 574  374  HOH HOH B . 
F 3 HOH 175 575  949  HOH HOH B . 
F 3 HOH 176 576  209  HOH HOH B . 
F 3 HOH 177 577  944  HOH HOH B . 
F 3 HOH 178 578  984  HOH HOH B . 
F 3 HOH 179 579  1391 HOH HOH B . 
F 3 HOH 180 580  664  HOH HOH B . 
F 3 HOH 181 581  894  HOH HOH B . 
F 3 HOH 182 582  64   HOH HOH B . 
F 3 HOH 183 583  416  HOH HOH B . 
F 3 HOH 184 584  381  HOH HOH B . 
F 3 HOH 185 585  792  HOH HOH B . 
F 3 HOH 186 586  896  HOH HOH B . 
F 3 HOH 187 587  1352 HOH HOH B . 
F 3 HOH 188 588  398  HOH HOH B . 
F 3 HOH 189 589  169  HOH HOH B . 
F 3 HOH 190 590  1224 HOH HOH B . 
F 3 HOH 191 591  376  HOH HOH B . 
F 3 HOH 192 592  32   HOH HOH B . 
F 3 HOH 193 593  430  HOH HOH B . 
F 3 HOH 194 594  7    HOH HOH B . 
F 3 HOH 195 595  226  HOH HOH B . 
F 3 HOH 196 596  189  HOH HOH B . 
F 3 HOH 197 597  89   HOH HOH B . 
F 3 HOH 198 598  774  HOH HOH B . 
F 3 HOH 199 599  51   HOH HOH B . 
F 3 HOH 200 600  996  HOH HOH B . 
F 3 HOH 201 601  947  HOH HOH B . 
F 3 HOH 202 602  220  HOH HOH B . 
F 3 HOH 203 603  1104 HOH HOH B . 
F 3 HOH 204 604  270  HOH HOH B . 
F 3 HOH 205 605  639  HOH HOH B . 
F 3 HOH 206 606  1007 HOH HOH B . 
F 3 HOH 207 607  798  HOH HOH B . 
F 3 HOH 208 608  906  HOH HOH B . 
F 3 HOH 209 609  1223 HOH HOH B . 
F 3 HOH 210 610  310  HOH HOH B . 
F 3 HOH 211 611  9    HOH HOH B . 
F 3 HOH 212 612  540  HOH HOH B . 
F 3 HOH 213 613  135  HOH HOH B . 
F 3 HOH 214 614  163  HOH HOH B . 
F 3 HOH 215 615  155  HOH HOH B . 
F 3 HOH 216 616  264  HOH HOH B . 
F 3 HOH 217 617  874  HOH HOH B . 
F 3 HOH 218 618  1133 HOH HOH B . 
F 3 HOH 219 619  362  HOH HOH B . 
F 3 HOH 220 620  768  HOH HOH B . 
F 3 HOH 221 621  33   HOH HOH B . 
F 3 HOH 222 622  872  HOH HOH B . 
F 3 HOH 223 623  59   HOH HOH B . 
F 3 HOH 224 624  394  HOH HOH B . 
F 3 HOH 225 625  181  HOH HOH B . 
F 3 HOH 226 626  129  HOH HOH B . 
F 3 HOH 227 627  283  HOH HOH B . 
F 3 HOH 228 628  234  HOH HOH B . 
F 3 HOH 229 629  202  HOH HOH B . 
F 3 HOH 230 630  1017 HOH HOH B . 
F 3 HOH 231 631  88   HOH HOH B . 
F 3 HOH 232 632  44   HOH HOH B . 
F 3 HOH 233 633  1387 HOH HOH B . 
F 3 HOH 234 634  300  HOH HOH B . 
F 3 HOH 235 635  541  HOH HOH B . 
F 3 HOH 236 636  337  HOH HOH B . 
F 3 HOH 237 637  132  HOH HOH B . 
F 3 HOH 238 638  103  HOH HOH B . 
F 3 HOH 239 639  828  HOH HOH B . 
F 3 HOH 240 640  994  HOH HOH B . 
F 3 HOH 241 641  295  HOH HOH B . 
F 3 HOH 242 642  241  HOH HOH B . 
F 3 HOH 243 643  891  HOH HOH B . 
F 3 HOH 244 644  247  HOH HOH B . 
F 3 HOH 245 645  831  HOH HOH B . 
F 3 HOH 246 646  1115 HOH HOH B . 
F 3 HOH 247 647  813  HOH HOH B . 
F 3 HOH 248 648  1276 HOH HOH B . 
F 3 HOH 249 649  336  HOH HOH B . 
F 3 HOH 250 650  588  HOH HOH B . 
F 3 HOH 251 651  314  HOH HOH B . 
F 3 HOH 252 652  167  HOH HOH B . 
F 3 HOH 253 653  501  HOH HOH B . 
F 3 HOH 254 654  516  HOH HOH B . 
F 3 HOH 255 655  291  HOH HOH B . 
F 3 HOH 256 656  1248 HOH HOH B . 
F 3 HOH 257 657  437  HOH HOH B . 
F 3 HOH 258 658  486  HOH HOH B . 
F 3 HOH 259 659  710  HOH HOH B . 
F 3 HOH 260 660  963  HOH HOH B . 
F 3 HOH 261 661  299  HOH HOH B . 
F 3 HOH 262 662  815  HOH HOH B . 
F 3 HOH 263 663  200  HOH HOH B . 
F 3 HOH 264 664  204  HOH HOH B . 
F 3 HOH 265 665  1044 HOH HOH B . 
F 3 HOH 266 666  401  HOH HOH B . 
F 3 HOH 267 667  29   HOH HOH B . 
F 3 HOH 268 668  35   HOH HOH B . 
F 3 HOH 269 669  930  HOH HOH B . 
F 3 HOH 270 670  706  HOH HOH B . 
F 3 HOH 271 671  331  HOH HOH B . 
F 3 HOH 272 672  1201 HOH HOH B . 
F 3 HOH 273 673  136  HOH HOH B . 
F 3 HOH 274 674  1326 HOH HOH B . 
F 3 HOH 275 675  46   HOH HOH B . 
F 3 HOH 276 676  31   HOH HOH B . 
F 3 HOH 277 677  497  HOH HOH B . 
F 3 HOH 278 678  1197 HOH HOH B . 
F 3 HOH 279 679  602  HOH HOH B . 
F 3 HOH 280 680  38   HOH HOH B . 
F 3 HOH 281 681  708  HOH HOH B . 
F 3 HOH 282 682  975  HOH HOH B . 
F 3 HOH 283 683  215  HOH HOH B . 
F 3 HOH 284 684  43   HOH HOH B . 
F 3 HOH 285 685  1354 HOH HOH B . 
F 3 HOH 286 686  1073 HOH HOH B . 
F 3 HOH 287 687  491  HOH HOH B . 
F 3 HOH 288 688  378  HOH HOH B . 
F 3 HOH 289 689  296  HOH HOH B . 
F 3 HOH 290 690  983  HOH HOH B . 
F 3 HOH 291 691  805  HOH HOH B . 
F 3 HOH 292 692  1096 HOH HOH B . 
F 3 HOH 293 693  380  HOH HOH B . 
F 3 HOH 294 694  1198 HOH HOH B . 
F 3 HOH 295 695  1196 HOH HOH B . 
F 3 HOH 296 696  688  HOH HOH B . 
F 3 HOH 297 697  955  HOH HOH B . 
F 3 HOH 298 698  931  HOH HOH B . 
F 3 HOH 299 699  744  HOH HOH B . 
F 3 HOH 300 700  738  HOH HOH B . 
F 3 HOH 301 701  734  HOH HOH B . 
F 3 HOH 302 702  693  HOH HOH B . 
F 3 HOH 303 703  1031 HOH HOH B . 
F 3 HOH 304 704  392  HOH HOH B . 
F 3 HOH 305 705  349  HOH HOH B . 
F 3 HOH 306 706  756  HOH HOH B . 
F 3 HOH 307 707  328  HOH HOH B . 
F 3 HOH 308 708  326  HOH HOH B . 
F 3 HOH 309 709  1099 HOH HOH B . 
F 3 HOH 310 710  332  HOH HOH B . 
F 3 HOH 311 711  463  HOH HOH B . 
F 3 HOH 312 712  753  HOH HOH B . 
F 3 HOH 313 713  770  HOH HOH B . 
F 3 HOH 314 714  464  HOH HOH B . 
F 3 HOH 315 715  940  HOH HOH B . 
F 3 HOH 316 716  713  HOH HOH B . 
F 3 HOH 317 717  1412 HOH HOH B . 
F 3 HOH 318 718  177  HOH HOH B . 
F 3 HOH 319 719  42   HOH HOH B . 
F 3 HOH 320 720  5    HOH HOH B . 
F 3 HOH 321 721  723  HOH HOH B . 
F 3 HOH 322 722  284  HOH HOH B . 
F 3 HOH 323 723  164  HOH HOH B . 
F 3 HOH 324 724  175  HOH HOH B . 
F 3 HOH 325 725  58   HOH HOH B . 
F 3 HOH 326 726  236  HOH HOH B . 
F 3 HOH 327 727  321  HOH HOH B . 
F 3 HOH 328 728  49   HOH HOH B . 
F 3 HOH 329 729  1338 HOH HOH B . 
F 3 HOH 330 730  481  HOH HOH B . 
F 3 HOH 331 731  598  HOH HOH B . 
F 3 HOH 332 732  726  HOH HOH B . 
F 3 HOH 333 733  859  HOH HOH B . 
F 3 HOH 334 734  591  HOH HOH B . 
F 3 HOH 335 735  325  HOH HOH B . 
F 3 HOH 336 736  1117 HOH HOH B . 
F 3 HOH 337 737  619  HOH HOH B . 
F 3 HOH 338 738  1236 HOH HOH B . 
F 3 HOH 339 739  109  HOH HOH B . 
F 3 HOH 340 740  396  HOH HOH B . 
F 3 HOH 341 741  341  HOH HOH B . 
F 3 HOH 342 742  635  HOH HOH B . 
F 3 HOH 343 743  461  HOH HOH B . 
F 3 HOH 344 744  1242 HOH HOH B . 
F 3 HOH 345 745  939  HOH HOH B . 
F 3 HOH 346 746  902  HOH HOH B . 
F 3 HOH 347 747  285  HOH HOH B . 
F 3 HOH 348 748  690  HOH HOH B . 
F 3 HOH 349 749  316  HOH HOH B . 
F 3 HOH 350 750  1165 HOH HOH B . 
F 3 HOH 351 751  441  HOH HOH B . 
F 3 HOH 352 752  269  HOH HOH B . 
F 3 HOH 353 753  157  HOH HOH B . 
F 3 HOH 354 754  615  HOH HOH B . 
F 3 HOH 355 755  803  HOH HOH B . 
F 3 HOH 356 756  858  HOH HOH B . 
F 3 HOH 357 757  529  HOH HOH B . 
F 3 HOH 358 758  676  HOH HOH B . 
F 3 HOH 359 759  666  HOH HOH B . 
F 3 HOH 360 760  162  HOH HOH B . 
F 3 HOH 361 761  725  HOH HOH B . 
F 3 HOH 362 762  656  HOH HOH B . 
F 3 HOH 363 763  450  HOH HOH B . 
F 3 HOH 364 764  1339 HOH HOH B . 
F 3 HOH 365 765  69   HOH HOH B . 
F 3 HOH 366 766  73   HOH HOH B . 
F 3 HOH 367 767  741  HOH HOH B . 
F 3 HOH 368 768  221  HOH HOH B . 
F 3 HOH 369 769  838  HOH HOH B . 
F 3 HOH 370 770  185  HOH HOH B . 
F 3 HOH 371 771  124  HOH HOH B . 
F 3 HOH 372 772  480  HOH HOH B . 
F 3 HOH 373 773  449  HOH HOH B . 
F 3 HOH 374 774  414  HOH HOH B . 
F 3 HOH 375 775  695  HOH HOH B . 
F 3 HOH 376 776  192  HOH HOH B . 
F 3 HOH 377 777  95   HOH HOH B . 
F 3 HOH 378 778  448  HOH HOH B . 
F 3 HOH 379 779  297  HOH HOH B . 
F 3 HOH 380 780  985  HOH HOH B . 
F 3 HOH 381 781  1255 HOH HOH B . 
F 3 HOH 382 782  1398 HOH HOH B . 
F 3 HOH 383 783  218  HOH HOH B . 
F 3 HOH 384 784  608  HOH HOH B . 
F 3 HOH 385 785  988  HOH HOH B . 
F 3 HOH 386 786  298  HOH HOH B . 
F 3 HOH 387 787  717  HOH HOH B . 
F 3 HOH 388 788  113  HOH HOH B . 
F 3 HOH 389 789  371  HOH HOH B . 
F 3 HOH 390 790  822  HOH HOH B . 
F 3 HOH 391 791  678  HOH HOH B . 
F 3 HOH 392 792  1369 HOH HOH B . 
F 3 HOH 393 793  323  HOH HOH B . 
F 3 HOH 394 794  459  HOH HOH B . 
F 3 HOH 395 795  1321 HOH HOH B . 
F 3 HOH 396 796  1409 HOH HOH B . 
F 3 HOH 397 797  993  HOH HOH B . 
F 3 HOH 398 798  379  HOH HOH B . 
F 3 HOH 399 799  307  HOH HOH B . 
F 3 HOH 400 800  445  HOH HOH B . 
F 3 HOH 401 801  235  HOH HOH B . 
F 3 HOH 402 802  763  HOH HOH B . 
F 3 HOH 403 803  701  HOH HOH B . 
F 3 HOH 404 804  699  HOH HOH B . 
F 3 HOH 405 805  1378 HOH HOH B . 
F 3 HOH 406 806  311  HOH HOH B . 
F 3 HOH 407 807  1126 HOH HOH B . 
F 3 HOH 408 808  1167 HOH HOH B . 
F 3 HOH 409 809  1327 HOH HOH B . 
F 3 HOH 410 810  1348 HOH HOH B . 
F 3 HOH 411 811  1050 HOH HOH B . 
F 3 HOH 412 812  684  HOH HOH B . 
F 3 HOH 413 813  662  HOH HOH B . 
F 3 HOH 414 814  194  HOH HOH B . 
F 3 HOH 415 815  1011 HOH HOH B . 
F 3 HOH 416 816  355  HOH HOH B . 
F 3 HOH 417 817  159  HOH HOH B . 
F 3 HOH 418 818  366  HOH HOH B . 
F 3 HOH 419 819  945  HOH HOH B . 
F 3 HOH 420 820  427  HOH HOH B . 
F 3 HOH 421 821  890  HOH HOH B . 
F 3 HOH 422 822  428  HOH HOH B . 
F 3 HOH 423 823  17   HOH HOH B . 
F 3 HOH 424 824  698  HOH HOH B . 
F 3 HOH 425 825  345  HOH HOH B . 
F 3 HOH 426 826  649  HOH HOH B . 
F 3 HOH 427 827  1199 HOH HOH B . 
F 3 HOH 428 828  962  HOH HOH B . 
F 3 HOH 429 829  834  HOH HOH B . 
F 3 HOH 430 830  442  HOH HOH B . 
F 3 HOH 431 831  1008 HOH HOH B . 
F 3 HOH 432 832  855  HOH HOH B . 
F 3 HOH 433 833  439  HOH HOH B . 
F 3 HOH 434 834  1150 HOH HOH B . 
F 3 HOH 435 835  1089 HOH HOH B . 
F 3 HOH 436 836  1052 HOH HOH B . 
F 3 HOH 437 837  827  HOH HOH B . 
F 3 HOH 438 838  599  HOH HOH B . 
F 3 HOH 439 839  1400 HOH HOH B . 
F 3 HOH 440 840  976  HOH HOH B . 
F 3 HOH 441 841  357  HOH HOH B . 
F 3 HOH 442 842  1079 HOH HOH B . 
F 3 HOH 443 843  395  HOH HOH B . 
F 3 HOH 444 844  938  HOH HOH B . 
F 3 HOH 445 845  1171 HOH HOH B . 
F 3 HOH 446 846  990  HOH HOH B . 
F 3 HOH 447 847  403  HOH HOH B . 
F 3 HOH 448 848  1097 HOH HOH B . 
F 3 HOH 449 849  1274 HOH HOH B . 
F 3 HOH 450 850  754  HOH HOH B . 
F 3 HOH 451 851  1069 HOH HOH B . 
F 3 HOH 452 852  1234 HOH HOH B . 
F 3 HOH 453 853  646  HOH HOH B . 
F 3 HOH 454 854  883  HOH HOH B . 
F 3 HOH 455 855  1335 HOH HOH B . 
F 3 HOH 456 856  919  HOH HOH B . 
F 3 HOH 457 857  989  HOH HOH B . 
F 3 HOH 458 858  1170 HOH HOH B . 
F 3 HOH 459 859  1139 HOH HOH B . 
F 3 HOH 460 860  766  HOH HOH B . 
F 3 HOH 461 861  851  HOH HOH B . 
F 3 HOH 462 862  1214 HOH HOH B . 
F 3 HOH 463 863  925  HOH HOH B . 
F 3 HOH 464 864  476  HOH HOH B . 
F 3 HOH 465 865  821  HOH HOH B . 
F 3 HOH 466 866  520  HOH HOH B . 
F 3 HOH 467 867  1252 HOH HOH B . 
F 3 HOH 468 868  1296 HOH HOH B . 
F 3 HOH 469 869  1382 HOH HOH B . 
F 3 HOH 470 870  1028 HOH HOH B . 
F 3 HOH 471 871  1178 HOH HOH B . 
F 3 HOH 472 872  614  HOH HOH B . 
F 3 HOH 473 873  1047 HOH HOH B . 
F 3 HOH 474 874  96   HOH HOH B . 
F 3 HOH 475 875  1283 HOH HOH B . 
F 3 HOH 476 876  1053 HOH HOH B . 
F 3 HOH 477 877  1207 HOH HOH B . 
F 3 HOH 478 878  879  HOH HOH B . 
F 3 HOH 479 879  1219 HOH HOH B . 
F 3 HOH 480 880  1161 HOH HOH B . 
F 3 HOH 481 881  875  HOH HOH B . 
F 3 HOH 482 882  1288 HOH HOH B . 
F 3 HOH 483 883  1399 HOH HOH B . 
F 3 HOH 484 884  905  HOH HOH B . 
F 3 HOH 485 885  1364 HOH HOH B . 
F 3 HOH 486 886  715  HOH HOH B . 
F 3 HOH 487 887  621  HOH HOH B . 
F 3 HOH 488 888  809  HOH HOH B . 
F 3 HOH 489 889  1384 HOH HOH B . 
F 3 HOH 490 890  1175 HOH HOH B . 
F 3 HOH 491 891  673  HOH HOH B . 
F 3 HOH 492 892  1218 HOH HOH B . 
F 3 HOH 493 893  133  HOH HOH B . 
F 3 HOH 494 894  1420 HOH HOH B . 
F 3 HOH 495 895  257  HOH HOH B . 
F 3 HOH 496 896  1312 HOH HOH B . 
F 3 HOH 497 897  1260 HOH HOH B . 
F 3 HOH 498 898  991  HOH HOH B . 
F 3 HOH 499 899  1148 HOH HOH B . 
F 3 HOH 500 900  1233 HOH HOH B . 
F 3 HOH 501 901  594  HOH HOH B . 
F 3 HOH 502 902  363  HOH HOH B . 
F 3 HOH 503 903  759  HOH HOH B . 
F 3 HOH 504 904  836  HOH HOH B . 
F 3 HOH 505 905  1357 HOH HOH B . 
F 3 HOH 506 906  213  HOH HOH B . 
F 3 HOH 507 907  610  HOH HOH B . 
F 3 HOH 508 908  1413 HOH HOH B . 
F 3 HOH 509 909  1158 HOH HOH B . 
F 3 HOH 510 910  712  HOH HOH B . 
F 3 HOH 511 911  1090 HOH HOH B . 
F 3 HOH 512 912  1220 HOH HOH B . 
F 3 HOH 513 913  275  HOH HOH B . 
F 3 HOH 514 914  1107 HOH HOH B . 
F 3 HOH 515 915  212  HOH HOH B . 
F 3 HOH 516 916  606  HOH HOH B . 
F 3 HOH 517 917  279  HOH HOH B . 
F 3 HOH 518 918  1262 HOH HOH B . 
F 3 HOH 519 919  847  HOH HOH B . 
F 3 HOH 520 920  861  HOH HOH B . 
F 3 HOH 521 921  1082 HOH HOH B . 
F 3 HOH 522 922  500  HOH HOH B . 
F 3 HOH 523 923  977  HOH HOH B . 
F 3 HOH 524 924  1111 HOH HOH B . 
F 3 HOH 525 925  677  HOH HOH B . 
F 3 HOH 526 926  1100 HOH HOH B . 
F 3 HOH 527 927  1259 HOH HOH B . 
F 3 HOH 528 928  148  HOH HOH B . 
F 3 HOH 529 929  1351 HOH HOH B . 
F 3 HOH 530 930  1128 HOH HOH B . 
F 3 HOH 531 931  1122 HOH HOH B . 
F 3 HOH 532 932  1200 HOH HOH B . 
F 3 HOH 533 933  1068 HOH HOH B . 
F 3 HOH 534 934  783  HOH HOH B . 
F 3 HOH 535 935  586  HOH HOH B . 
F 3 HOH 536 936  663  HOH HOH B . 
F 3 HOH 537 937  1087 HOH HOH B . 
F 3 HOH 538 938  399  HOH HOH B . 
F 3 HOH 539 939  762  HOH HOH B . 
F 3 HOH 540 940  1418 HOH HOH B . 
F 3 HOH 541 941  400  HOH HOH B . 
F 3 HOH 542 942  1194 HOH HOH B . 
F 3 HOH 543 943  632  HOH HOH B . 
F 3 HOH 544 944  1310 HOH HOH B . 
F 3 HOH 545 945  579  HOH HOH B . 
F 3 HOH 546 946  1080 HOH HOH B . 
F 3 HOH 547 947  466  HOH HOH B . 
F 3 HOH 548 948  1078 HOH HOH B . 
F 3 HOH 549 949  670  HOH HOH B . 
F 3 HOH 550 950  1046 HOH HOH B . 
F 3 HOH 551 951  1204 HOH HOH B . 
F 3 HOH 552 952  333  HOH HOH B . 
F 3 HOH 553 953  889  HOH HOH B . 
F 3 HOH 554 954  1229 HOH HOH B . 
F 3 HOH 555 955  1330 HOH HOH B . 
F 3 HOH 556 956  473  HOH HOH B . 
F 3 HOH 557 957  934  HOH HOH B . 
F 3 HOH 558 958  724  HOH HOH B . 
F 3 HOH 559 959  953  HOH HOH B . 
F 3 HOH 560 960  1392 HOH HOH B . 
F 3 HOH 561 961  206  HOH HOH B . 
F 3 HOH 562 962  176  HOH HOH B . 
F 3 HOH 563 963  620  HOH HOH B . 
F 3 HOH 564 964  681  HOH HOH B . 
F 3 HOH 565 965  709  HOH HOH B . 
F 3 HOH 566 966  1282 HOH HOH B . 
F 3 HOH 567 967  765  HOH HOH B . 
F 3 HOH 568 968  320  HOH HOH B . 
F 3 HOH 569 969  1265 HOH HOH B . 
F 3 HOH 570 970  1143 HOH HOH B . 
F 3 HOH 571 971  995  HOH HOH B . 
F 3 HOH 572 972  644  HOH HOH B . 
F 3 HOH 573 973  719  HOH HOH B . 
F 3 HOH 574 974  1287 HOH HOH B . 
F 3 HOH 575 975  837  HOH HOH B . 
F 3 HOH 576 976  1290 HOH HOH B . 
F 3 HOH 577 977  785  HOH HOH B . 
F 3 HOH 578 978  893  HOH HOH B . 
F 3 HOH 579 979  1042 HOH HOH B . 
F 3 HOH 580 980  1032 HOH HOH B . 
F 3 HOH 581 981  227  HOH HOH B . 
F 3 HOH 582 982  843  HOH HOH B . 
F 3 HOH 583 983  587  HOH HOH B . 
F 3 HOH 584 984  425  HOH HOH B . 
F 3 HOH 585 985  271  HOH HOH B . 
F 3 HOH 586 986  691  HOH HOH B . 
F 3 HOH 587 987  1394 HOH HOH B . 
F 3 HOH 588 988  672  HOH HOH B . 
F 3 HOH 589 989  1408 HOH HOH B . 
F 3 HOH 590 990  436  HOH HOH B . 
F 3 HOH 591 991  971  HOH HOH B . 
F 3 HOH 592 992  751  HOH HOH B . 
F 3 HOH 593 993  1163 HOH HOH B . 
F 3 HOH 594 994  1086 HOH HOH B . 
F 3 HOH 595 995  1389 HOH HOH B . 
F 3 HOH 596 996  1371 HOH HOH B . 
F 3 HOH 597 997  869  HOH HOH B . 
F 3 HOH 598 998  571  HOH HOH B . 
F 3 HOH 599 999  512  HOH HOH B . 
F 3 HOH 600 1000 1216 HOH HOH B . 
F 3 HOH 601 1001 1006 HOH HOH B . 
F 3 HOH 602 1002 866  HOH HOH B . 
F 3 HOH 603 1003 647  HOH HOH B . 
F 3 HOH 604 1004 1141 HOH HOH B . 
F 3 HOH 605 1005 143  HOH HOH B . 
F 3 HOH 606 1006 1130 HOH HOH B . 
F 3 HOH 607 1007 829  HOH HOH B . 
F 3 HOH 608 1008 1256 HOH HOH B . 
F 3 HOH 609 1009 731  HOH HOH B . 
F 3 HOH 610 1010 1094 HOH HOH B . 
F 3 HOH 611 1011 1284 HOH HOH B . 
F 3 HOH 612 1012 870  HOH HOH B . 
F 3 HOH 613 1013 1245 HOH HOH B . 
F 3 HOH 614 1014 790  HOH HOH B . 
F 3 HOH 615 1015 1003 HOH HOH B . 
F 3 HOH 616 1016 924  HOH HOH B . 
F 3 HOH 617 1017 1209 HOH HOH B . 
F 3 HOH 618 1018 1291 HOH HOH B . 
F 3 HOH 619 1019 1363 HOH HOH B . 
F 3 HOH 620 1020 581  HOH HOH B . 
F 3 HOH 621 1021 943  HOH HOH B . 
F 3 HOH 622 1022 1160 HOH HOH B . 
F 3 HOH 623 1023 845  HOH HOH B . 
F 3 HOH 624 1024 1258 HOH HOH B . 
F 3 HOH 625 1025 538  HOH HOH B . 
F 3 HOH 626 1026 1208 HOH HOH B . 
F 3 HOH 627 1027 1345 HOH HOH B . 
F 3 HOH 628 1028 1383 HOH HOH B . 
F 3 HOH 629 1029 519  HOH HOH B . 
F 3 HOH 630 1030 1373 HOH HOH B . 
F 3 HOH 631 1031 685  HOH HOH B . 
F 3 HOH 632 1032 979  HOH HOH B . 
F 3 HOH 633 1033 1355 HOH HOH B . 
F 3 HOH 634 1034 1419 HOH HOH B . 
F 3 HOH 635 1035 1337 HOH HOH B . 
F 3 HOH 636 1036 867  HOH HOH B . 
F 3 HOH 637 1037 1341 HOH HOH B . 
F 3 HOH 638 1038 844  HOH HOH B . 
F 3 HOH 639 1039 1254 HOH HOH B . 
F 3 HOH 640 1040 1081 HOH HOH B . 
F 3 HOH 641 1041 1361 HOH HOH B . 
F 3 HOH 642 1042 917  HOH HOH B . 
F 3 HOH 643 1043 978  HOH HOH B . 
F 3 HOH 644 1044 806  HOH HOH B . 
F 3 HOH 645 1045 1187 HOH HOH B . 
F 3 HOH 646 1046 1026 HOH HOH B . 
F 3 HOH 647 1047 1147 HOH HOH B . 
F 3 HOH 648 1048 1381 HOH HOH B . 
F 3 HOH 649 1049 773  HOH HOH B . 
F 3 HOH 650 1050 603  HOH HOH B . 
F 3 HOH 651 1051 1305 HOH HOH B . 
F 3 HOH 652 1052 1247 HOH HOH B . 
F 3 HOH 653 1053 556  HOH HOH B . 
F 3 HOH 654 1054 518  HOH HOH B . 
F 3 HOH 655 1055 286  HOH HOH B . 
F 3 HOH 656 1056 593  HOH HOH B . 
F 3 HOH 657 1057 854  HOH HOH B . 
F 3 HOH 658 1058 968  HOH HOH B . 
F 3 HOH 659 1059 1253 HOH HOH B . 
F 3 HOH 660 1060 1106 HOH HOH B . 
F 3 HOH 661 1061 590  HOH HOH B . 
F 3 HOH 662 1062 548  HOH HOH B . 
F 3 HOH 663 1063 1102 HOH HOH B . 
F 3 HOH 664 1064 718  HOH HOH B . 
F 3 HOH 665 1065 1123 HOH HOH B . 
F 3 HOH 666 1066 1367 HOH HOH B . 
F 3 HOH 667 1067 886  HOH HOH B . 
F 3 HOH 668 1068 914  HOH HOH B . 
F 3 HOH 669 1069 820  HOH HOH B . 
F 3 HOH 670 1070 1131 HOH HOH B . 
F 3 HOH 671 1071 1333 HOH HOH B . 
F 3 HOH 672 1072 502  HOH HOH B . 
F 3 HOH 673 1073 1270 HOH HOH B . 
F 3 HOH 674 1074 973  HOH HOH B . 
F 3 HOH 675 1075 895  HOH HOH B . 
F 3 HOH 676 1076 686  HOH HOH B . 
F 3 HOH 677 1077 358  HOH HOH B . 
F 3 HOH 678 1078 954  HOH HOH B . 
F 3 HOH 679 1079 1039 HOH HOH B . 
F 3 HOH 680 1080 1374 HOH HOH B . 
F 3 HOH 681 1081 650  HOH HOH B . 
F 3 HOH 682 1082 1309 HOH HOH B . 
F 3 HOH 683 1083 1286 HOH HOH B . 
F 3 HOH 684 1084 1135 HOH HOH B . 
F 3 HOH 685 1085 1061 HOH HOH B . 
F 3 HOH 686 1086 696  HOH HOH B . 
F 3 HOH 687 1087 289  HOH HOH B . 
F 3 HOH 688 1088 960  HOH HOH B . 
F 3 HOH 689 1089 1240 HOH HOH B . 
F 3 HOH 690 1090 1370 HOH HOH B . 
F 3 HOH 691 1091 1386 HOH HOH B . 
F 3 HOH 692 1092 1393 HOH HOH B . 
F 3 HOH 693 1093 1272 HOH HOH B . 
F 3 HOH 694 1094 824  HOH HOH B . 
F 3 HOH 695 1095 1101 HOH HOH B . 
F 3 HOH 696 1096 65   HOH HOH B . 
F 3 HOH 697 1097 736  HOH HOH B . 
F 3 HOH 698 1098 1401 HOH HOH B . 
F 3 HOH 699 1099 1325 HOH HOH B . 
F 3 HOH 700 1100 1040 HOH HOH B . 
F 3 HOH 701 1101 1176 HOH HOH B . 
F 3 HOH 702 1102 523  HOH HOH B . 
F 3 HOH 703 1103 490  HOH HOH B . 
F 3 HOH 704 1104 1027 HOH HOH B . 
F 3 HOH 705 1105 1172 HOH HOH B . 
F 3 HOH 706 1106 1091 HOH HOH B . 
F 3 HOH 707 1107 1025 HOH HOH B . 
F 3 HOH 708 1108 533  HOH HOH B . 
F 3 HOH 709 1109 720  HOH HOH B . 
F 3 HOH 710 1110 964  HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLN 19  ? NE2 ? A GLN 53  NE2 
2  1 Y 1 A GLN 21  ? CD  ? A GLN 55  CD  
3  1 Y 1 A GLN 21  ? OE1 ? A GLN 55  OE1 
4  1 Y 1 A GLN 21  ? NE2 ? A GLN 55  NE2 
5  1 Y 1 A GLU 22  ? CD  ? A GLU 56  CD  
6  1 Y 1 A GLU 22  ? OE1 ? A GLU 56  OE1 
7  1 Y 1 A GLU 22  ? OE2 ? A GLU 56  OE2 
8  1 Y 1 A GLU 227 ? CD  ? A GLU 261 CD  
9  1 Y 1 A GLU 227 ? OE1 ? A GLU 261 OE1 
10 1 Y 1 A GLU 227 ? OE2 ? A GLU 261 OE2 
11 1 Y 1 A GLU 283 ? CG  ? A GLU 317 CG  
12 1 Y 1 A GLU 283 ? CD  ? A GLU 317 CD  
13 1 Y 1 A GLU 283 ? OE1 ? A GLU 317 OE1 
14 1 Y 1 A GLU 283 ? OE2 ? A GLU 317 OE2 
15 1 Y 1 A GLU 296 ? CG  ? A GLU 330 CG  
16 1 Y 1 A GLU 296 ? CD  ? A GLU 330 CD  
17 1 Y 1 A GLU 296 ? OE1 ? A GLU 330 OE1 
18 1 Y 1 A GLU 296 ? OE2 ? A GLU 330 OE2 
19 1 Y 1 A ASP 297 ? CG  ? A ASP 331 CG  
20 1 Y 1 A ASP 297 ? OD1 ? A ASP 331 OD1 
21 1 Y 1 A ASP 297 ? OD2 ? A ASP 331 OD2 
22 1 Y 1 B LYS 90  ? NZ  ? B LYS 124 NZ  
23 1 Y 1 B LYS 93  ? CE  ? B LYS 127 CE  
24 1 Y 1 B LYS 93  ? NZ  ? B LYS 127 NZ  
25 1 Y 1 B GLU 194 ? OE1 ? B GLU 228 OE1 
26 1 Y 1 B GLU 194 ? OE2 ? B GLU 228 OE2 
27 1 Y 1 B LYS 267 ? CE  ? B LYS 301 CE  
28 1 Y 1 B LYS 267 ? NZ  ? B LYS 301 NZ  
29 1 Y 1 B ASP 286 ? CG  ? B ASP 320 CG  
30 1 Y 1 B ASP 286 ? OD1 ? B ASP 320 OD1 
31 1 Y 1 B ASP 286 ? OD2 ? B ASP 320 OD2 
32 1 Y 1 B GLU 296 ? CG  ? B GLU 330 CG  
33 1 Y 1 B GLU 296 ? CD  ? B GLU 330 CD  
34 1 Y 1 B GLU 296 ? OE1 ? B GLU 330 OE1 
35 1 Y 1 B GLU 296 ? OE2 ? B GLU 330 OE2 
36 1 Y 1 B GLU 303 ? CG  ? B GLU 337 CG  
37 1 Y 1 B GLU 303 ? CD  ? B GLU 337 CD  
38 1 Y 1 B GLU 303 ? OE1 ? B GLU 337 OE1 
39 1 Y 1 B GLU 303 ? OE2 ? B GLU 337 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? '(1.20.1_4487: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   113.66 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JOG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     54.741 
_cell.length_a_esd                 ? 
_cell.length_b                     138.390 
_cell.length_b_esd                 ? 
_cell.length_c                     62.866 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JOG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JOG 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.27 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.86 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'0.2M Sodium acetate trihydrate, 0.1M TRIS hydrochloride pH 8.5, 30% w/v Polyethylene glycol 4,000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            290 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-09-23 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97923 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL19U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97923 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL19U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9JOG 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.40 
_reflns.d_resolution_low                               39.83 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     167694 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          21.2 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.01 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.055 
_reflns.pdbx_Rpim_I_all                                0.022 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       1095501 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.051 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.40 
_reflns_shell.d_res_low                                     1.42 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           53878 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             8239 
_reflns_shell.percent_possible_obs                          100.0 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               6.5 
_reflns_shell.pdbx_chi_squared                              1.03 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     6.7 
_reflns_shell.pdbx_Rrim_I_all                               0.301 
_reflns_shell.pdbx_Rpim_I_all                               0.116 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.967 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.277 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9JOG 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.40 
_refine.ls_d_res_low                             34.60 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     167589 
_refine.ls_number_reflns_R_free                  2006 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.94 
_refine.ls_percent_reflns_R_free                 1.20 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1404 
_refine.ls_R_factor_R_free                       0.1553 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1402 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 14.59 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.10 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.40 
_refine_hist.d_res_low                        34.60 
_refine_hist.number_atoms_solvent             1405 
_refine_hist.number_atoms_total               7422 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5903 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         114 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008 ? 6231 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.280 ? 8496 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 7.081 ? 826  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.098 ? 947  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.008 ? 1073 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.40 1.44  . . 139 11805 100.00 . . . . 0.1705 . . . . . . . . . . . 0.1723 
'X-RAY DIFFRACTION' 1.44 1.47  . . 149 11770 100.00 . . . . 0.1635 . . . . . . . . . . . 0.1686 
'X-RAY DIFFRACTION' 1.47 1.52  . . 140 11797 100.00 . . . . 0.1596 . . . . . . . . . . . 0.1875 
'X-RAY DIFFRACTION' 1.52 1.57  . . 145 11844 100.00 . . . . 0.1510 . . . . . . . . . . . 0.1554 
'X-RAY DIFFRACTION' 1.57 1.62  . . 147 11798 100.00 . . . . 0.1470 . . . . . . . . . . . 0.1623 
'X-RAY DIFFRACTION' 1.62 1.69  . . 141 11765 100.00 . . . . 0.1471 . . . . . . . . . . . 0.1860 
'X-RAY DIFFRACTION' 1.69 1.76  . . 144 11862 100.00 . . . . 0.1440 . . . . . . . . . . . 0.1434 
'X-RAY DIFFRACTION' 1.76 1.86  . . 139 11830 100.00 . . . . 0.1434 . . . . . . . . . . . 0.1577 
'X-RAY DIFFRACTION' 1.86 1.97  . . 147 11798 100.00 . . . . 0.1445 . . . . . . . . . . . 0.1734 
'X-RAY DIFFRACTION' 1.97 2.13  . . 142 11829 100.00 . . . . 0.1333 . . . . . . . . . . . 0.1463 
'X-RAY DIFFRACTION' 2.13 2.34  . . 140 11821 100.00 . . . . 0.1312 . . . . . . . . . . . 0.1668 
'X-RAY DIFFRACTION' 2.34 2.68  . . 140 11854 100.00 . . . . 0.1335 . . . . . . . . . . . 0.1575 
'X-RAY DIFFRACTION' 2.68 3.37  . . 144 11868 100.00 . . . . 0.1386 . . . . . . . . . . . 0.1360 
'X-RAY DIFFRACTION' 3.37 34.60 . . 149 11942 100.00 . . . . 0.1351 . . . . . . . . . . . 0.1480 
# 
_struct.entry_id                     9JOG 
_struct.title                        'COMPLEX STRUCTURE OF ENDO-1,3-FUCANASE (FUN168D) WITH FUCOTETRAOSE FROM HOLOTHURIA TUBULOSA' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JOG 
_struct_keywords.text            'Endo-1.3-fucanase, GH168, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A1B1Y6G8_9FLAO 
_struct_ref.pdbx_db_accession          A0A1B1Y6G8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;STKNGIIELEQETEEELEQNQEIDYSNYPEFSWDTMPLYMHVRKNTAYTDEEINYLASFPLITLEKSQAQNTYGSTEEGT
LATASAIKLKNNKAKVLYYRNVVINWGNYKNDDEFISKNPSALLKNQNNELVYMPNGSTPFFDITKSFVQEYWLKSVEDM
VATPNIDGTFIDANIKVLVPSFFSSKVGVNKQAEIENSYFSMMSRLKESLSNNLILANIIRVRPEFEENGLEYLGYFNGS
YLEGFDSEAFGMSNAEYLVEGIEATQKAAQSGKIITMTLGLGEAIDNNTGIDDQREDVDLNDEELNKRVDYLLAIFLICA
EKYSYVYLHDGYLATNSAVWLHQFDQYKKALGAPLGKAIKNGYIYTRKFENLDVWLNLETQTATLTWKE
;
_struct_ref.pdbx_align_begin           22 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JOG A 35 ? 423 ? A0A1B1Y6G8 22 ? 410 ? 1 389 
2 1 9JOG B 35 ? 423 ? A0A1B1Y6G8 22 ? 410 ? 1 389 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9JOG MET A 1  ? UNP A0A1B1Y6G8 ? ? 'initiating methionine' -33 1  
1 9JOG GLY A 2  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -32 2  
1 9JOG SER A 3  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -31 3  
1 9JOG SER A 4  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -30 4  
1 9JOG HIS A 5  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -29 5  
1 9JOG HIS A 6  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -28 6  
1 9JOG HIS A 7  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -27 7  
1 9JOG HIS A 8  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -26 8  
1 9JOG HIS A 9  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -25 9  
1 9JOG HIS A 10 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -24 10 
1 9JOG SER A 11 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -23 11 
1 9JOG SER A 12 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -22 12 
1 9JOG GLY A 13 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -21 13 
1 9JOG LEU A 14 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -20 14 
1 9JOG VAL A 15 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -19 15 
1 9JOG PRO A 16 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -18 16 
1 9JOG ARG A 17 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -17 17 
1 9JOG GLY A 18 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -16 18 
1 9JOG SER A 19 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -15 19 
1 9JOG HIS A 20 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -14 20 
1 9JOG MET A 21 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -13 21 
1 9JOG ALA A 22 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -12 22 
1 9JOG SER A 23 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -11 23 
1 9JOG MET A 24 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -10 24 
1 9JOG THR A 25 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -9  25 
1 9JOG GLY A 26 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -8  26 
1 9JOG GLY A 27 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -7  27 
1 9JOG GLN A 28 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -6  28 
1 9JOG GLN A 29 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -5  29 
1 9JOG MET A 30 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -4  30 
1 9JOG GLY A 31 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -3  31 
1 9JOG ARG A 32 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -2  32 
1 9JOG GLY A 33 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -1  33 
1 9JOG SER A 34 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        0   34 
2 9JOG MET B 1  ? UNP A0A1B1Y6G8 ? ? 'initiating methionine' -33 35 
2 9JOG GLY B 2  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -32 36 
2 9JOG SER B 3  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -31 37 
2 9JOG SER B 4  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -30 38 
2 9JOG HIS B 5  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -29 39 
2 9JOG HIS B 6  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -28 40 
2 9JOG HIS B 7  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -27 41 
2 9JOG HIS B 8  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -26 42 
2 9JOG HIS B 9  ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -25 43 
2 9JOG HIS B 10 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -24 44 
2 9JOG SER B 11 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -23 45 
2 9JOG SER B 12 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -22 46 
2 9JOG GLY B 13 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -21 47 
2 9JOG LEU B 14 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -20 48 
2 9JOG VAL B 15 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -19 49 
2 9JOG PRO B 16 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -18 50 
2 9JOG ARG B 17 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -17 51 
2 9JOG GLY B 18 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -16 52 
2 9JOG SER B 19 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -15 53 
2 9JOG HIS B 20 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -14 54 
2 9JOG MET B 21 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -13 55 
2 9JOG ALA B 22 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -12 56 
2 9JOG SER B 23 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -11 57 
2 9JOG MET B 24 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -10 58 
2 9JOG THR B 25 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -9  59 
2 9JOG GLY B 26 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -8  60 
2 9JOG GLY B 27 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -7  61 
2 9JOG GLN B 28 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -6  62 
2 9JOG GLN B 29 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -5  63 
2 9JOG MET B 30 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -4  64 
2 9JOG GLY B 31 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -3  65 
2 9JOG ARG B 32 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -2  66 
2 9JOG GLY B 33 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        -1  67 
2 9JOG SER B 34 ? UNP A0A1B1Y6G8 ? ? 'expression tag'        0   68 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 83  ? SER A 92  ? THR A 49  SER A 58  1 ? 10 
HELX_P HELX_P2  AA2 ALA A 103 ? GLY A 108 ? ALA A 69  GLY A 74  1 ? 6  
HELX_P HELX_P3  AA3 SER A 109 ? ASN A 125 ? SER A 75  ASN A 91  1 ? 17 
HELX_P HELX_P4  AA4 TYR A 143 ? ASN A 153 ? TYR A 109 ASN A 119 1 ? 11 
HELX_P HELX_P5  AA5 PRO A 154 ? LEU A 157 ? PRO A 120 LEU A 123 5 ? 4  
HELX_P HELX_P6  AA6 LYS A 180 ? ALA A 196 ? LYS A 146 ALA A 162 1 ? 17 
HELX_P HELX_P7  AA7 ALA A 207 ? VAL A 213 ? ALA A 173 VAL A 179 1 ? 7  
HELX_P HELX_P8  AA8 VAL A 213 ? GLY A 222 ? VAL A 179 GLY A 188 1 ? 10 
HELX_P HELX_P9  AA9 GLY A 222 ? LEU A 244 ? GLY A 188 LEU A 210 1 ? 23 
HELX_P HELX_P10 AB1 GLY A 264 ? PHE A 271 ? GLY A 230 PHE A 237 5 ? 8  
HELX_P HELX_P11 AB2 SER A 287 ? SER A 305 ? SER A 253 SER A 271 1 ? 19 
HELX_P HELX_P12 AB3 LEU A 315 ? ASP A 320 ? LEU A 281 ASP A 286 1 ? 6  
HELX_P HELX_P13 AB4 ASP A 336 ? ALA A 354 ? ASP A 302 ALA A 320 1 ? 19 
HELX_P HELX_P14 AB5 LEU A 367 ? SER A 371 ? LEU A 333 SER A 337 5 ? 5  
HELX_P HELX_P15 AB6 PHE A 378 ? LYS A 382 ? PHE A 344 LYS A 348 5 ? 5  
HELX_P HELX_P16 AB7 THR B 83  ? SER B 92  ? THR B 49  SER B 58  1 ? 10 
HELX_P HELX_P17 AB8 ALA B 103 ? GLY B 108 ? ALA B 69  GLY B 74  1 ? 6  
HELX_P HELX_P18 AB9 SER B 109 ? ASN B 125 ? SER B 75  ASN B 91  1 ? 17 
HELX_P HELX_P19 AC1 TYR B 143 ? ASN B 153 ? TYR B 109 ASN B 119 1 ? 11 
HELX_P HELX_P20 AC2 PRO B 154 ? LEU B 157 ? PRO B 120 LEU B 123 5 ? 4  
HELX_P HELX_P21 AC3 LYS B 180 ? THR B 197 ? LYS B 146 THR B 163 1 ? 18 
HELX_P HELX_P22 AC4 ALA B 207 ? VAL B 213 ? ALA B 173 VAL B 179 1 ? 7  
HELX_P HELX_P23 AC5 PRO B 214 ? GLY B 222 ? PRO B 180 GLY B 188 1 ? 9  
HELX_P HELX_P24 AC6 GLY B 222 ? LEU B 244 ? GLY B 188 LEU B 210 1 ? 23 
HELX_P HELX_P25 AC7 GLY B 264 ? PHE B 271 ? GLY B 230 PHE B 237 5 ? 8  
HELX_P HELX_P26 AC8 SER B 287 ? SER B 305 ? SER B 253 SER B 271 1 ? 19 
HELX_P HELX_P27 AC9 LEU B 315 ? ASP B 320 ? LEU B 281 ASP B 286 1 ? 6  
HELX_P HELX_P28 AD1 ASP B 336 ? ALA B 354 ? ASP B 302 ALA B 320 1 ? 19 
HELX_P HELX_P29 AD2 LEU B 367 ? SER B 371 ? LEU B 333 SER B 337 5 ? 5  
HELX_P HELX_P30 AD3 PHE B 378 ? LYS B 382 ? PHE B 344 LYS B 348 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? C X6Y . O3 ? ? ? 1_555 C X6Y . C1 ? ? C X6Y 1 C X6Y 2 1_555 ? ? ? ? ? ? ? 1.370 ? ? 
covale2 covale one  ? C X6Y . O3 ? ? ? 1_555 C FUC . C1 ? ? C X6Y 2 C FUC 3 1_555 ? ? ? ? ? ? ? 1.365 ? ? 
covale3 covale both ? C FUC . O3 ? ? ? 1_555 C X2Y . C1 ? ? C FUC 3 C X2Y 4 1_555 ? ? ? ? ? ? ? 1.387 ? ? 
covale4 covale none ? D X6Y . O3 ? ? ? 1_555 D X6Y . C1 ? ? D X6Y 1 D X6Y 2 1_555 ? ? ? ? ? ? ? 1.361 ? ? 
covale5 covale one  ? D X6Y . O3 ? ? ? 1_555 D FUC . C1 ? ? D X6Y 2 D FUC 3 1_555 ? ? ? ? ? ? ? 1.363 ? ? 
covale6 covale both ? D FUC . O3 ? ? ? 1_555 D X2Y . C1 ? ? D FUC 3 D X2Y 4 1_555 ? ? ? ? ? ? ? 1.374 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 4 ? 
AA3 ? 8 ? 
AA4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA3 7 8 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 73  ? LYS A 78  ? TYR A 39  LYS A 44  
AA1 2 LEU A 95  ? GLN A 102 ? LEU A 61  GLN A 68  
AA1 3 LYS A 129 ? ASN A 135 ? LYS A 95  ASN A 101 
AA1 4 GLY A 202 ? ASP A 206 ? GLY A 168 ASP A 172 
AA1 5 LEU A 248 ? ASN A 252 ? LEU A 214 ASN A 218 
AA1 6 GLY A 273 ? LEU A 276 ? GLY A 239 LEU A 242 
AA1 7 ILE A 308 ? GLY A 314 ? ILE A 274 GLY A 280 
AA1 8 SER A 358 ? HIS A 363 ? SER A 324 HIS A 329 
AA2 1 ILE A 393 ? ASN A 395 ? ILE A 359 ASN A 361 
AA2 2 ILE A 398 ? PHE A 403 ? ILE A 364 PHE A 369 
AA2 3 LEU A 406 ? ASN A 411 ? LEU A 372 ASN A 377 
AA2 4 THR A 416 ? TRP A 421 ? THR A 382 TRP A 387 
AA3 1 TYR B 73  ? LYS B 78  ? TYR B 39  LYS B 44  
AA3 2 LEU B 95  ? GLN B 102 ? LEU B 61  GLN B 68  
AA3 3 LYS B 129 ? ASN B 135 ? LYS B 95  ASN B 101 
AA3 4 GLY B 202 ? ASP B 206 ? GLY B 168 ASP B 172 
AA3 5 LEU B 248 ? ASN B 252 ? LEU B 214 ASN B 218 
AA3 6 GLY B 273 ? LEU B 276 ? GLY B 239 LEU B 242 
AA3 7 ILE B 308 ? GLY B 314 ? ILE B 274 GLY B 280 
AA3 8 SER B 358 ? HIS B 363 ? SER B 324 HIS B 329 
AA4 1 ILE B 393 ? ASN B 395 ? ILE B 359 ASN B 361 
AA4 2 ILE B 398 ? PHE B 403 ? ILE B 364 PHE B 369 
AA4 3 LEU B 406 ? ASN B 411 ? LEU B 372 ASN B 377 
AA4 4 THR B 416 ? TRP B 421 ? THR B 382 TRP B 387 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N MET A 74  ? N MET A 40  O THR A 97  ? O THR A 63  
AA1 2 3 N ILE A 96  ? N ILE A 62  O LEU A 131 ? O LEU A 97  
AA1 3 4 N ARG A 134 ? N ARG A 100 O PHE A 204 ? O PHE A 170 
AA1 4 5 N ILE A 205 ? N ILE A 171 O LEU A 250 ? O LEU A 216 
AA1 5 6 N ALA A 251 ? N ALA A 217 O TYR A 275 ? O TYR A 241 
AA1 6 7 N LEU A 276 ? N LEU A 242 O THR A 310 ? O THR A 276 
AA1 7 8 N ILE A 309 ? N ILE A 275 O TYR A 359 ? O TYR A 325 
AA2 1 2 N ASN A 395 ? N ASN A 361 O ILE A 398 ? O ILE A 364 
AA2 2 3 N PHE A 403 ? N PHE A 369 O LEU A 406 ? O LEU A 372 
AA2 3 4 N ASN A 411 ? N ASN A 377 O THR A 416 ? O THR A 382 
AA3 1 2 N MET B 74  ? N MET B 40  O THR B 97  ? O THR B 63  
AA3 2 3 N ILE B 96  ? N ILE B 62  O LEU B 131 ? O LEU B 97  
AA3 3 4 N ARG B 134 ? N ARG B 100 O PHE B 204 ? O PHE B 170 
AA3 4 5 N ILE B 205 ? N ILE B 171 O LEU B 250 ? O LEU B 216 
AA3 5 6 N ALA B 251 ? N ALA B 217 O TYR B 275 ? O TYR B 241 
AA3 6 7 N LEU B 276 ? N LEU B 242 O THR B 310 ? O THR B 276 
AA3 7 8 N ILE B 309 ? N ILE B 275 O TYR B 359 ? O TYR B 325 
AA4 1 2 N ASN B 395 ? N ASN B 361 O ILE B 398 ? O ILE B 364 
AA4 2 3 N PHE B 403 ? N PHE B 369 O LEU B 406 ? O LEU B 372 
AA4 3 4 N ASN B 411 ? N ASN B 377 O THR B 416 ? O THR B 382 
# 
_pdbx_entry_details.entry_id                   9JOG 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 HH21 B ARG 308  ? ? O B HOH 403  ? ? 1.40 
2  1 HE21 B GLN 343  ? ? O B HOH 401  ? ? 1.49 
3  1 HG   A SER 247  ? A O A HOH 406  ? ? 1.59 
4  1 HD21 B ASN 361  ? ? O B HOH 408  ? ? 1.59 
5  1 O    A HOH 541  ? ? O A HOH 622  ? ? 1.82 
6  1 O    A HOH 758  ? ? O A HOH 829  ? ? 1.85 
7  1 O    B HOH 550  ? ? O B HOH 823  ? ? 1.85 
8  1 O    B HOH 403  ? ? O B HOH 424  ? ? 1.86 
9  1 O    A HOH 570  ? ? O A HOH 977  ? ? 1.93 
10 1 O    B HOH 954  ? ? O B HOH 1013 ? ? 1.95 
11 1 O    B HOH 538  ? ? O B HOH 713  ? ? 1.96 
12 1 O    A HOH 812  ? ? O A HOH 921  ? ? 1.96 
13 1 O    B HOH 932  ? ? O B HOH 994  ? ? 1.97 
14 1 O    A HOH 829  ? ? O A HOH 900  ? ? 2.00 
15 1 O    B HOH 1082 ? ? O B HOH 1090 ? ? 2.01 
16 1 O    B HOH 407  ? ? O B HOH 764  ? ? 2.01 
17 1 O    B HOH 469  ? ? O B HOH 813  ? ? 2.02 
18 1 O    B HOH 966  ? ? O B HOH 1028 ? ? 2.02 
19 1 O    B HOH 785  ? ? O B HOH 844  ? ? 2.02 
20 1 O    B HOH 578  ? ? O B HOH 955  ? ? 2.03 
21 1 NE2  B GLN 343  ? ? O B HOH 401  ? ? 2.04 
22 1 O    A HOH 835  ? ? O A HOH 863  ? ? 2.04 
23 1 OD2  B ASP 345  ? ? O B HOH 402  ? ? 2.04 
24 1 O    B HOH 983  ? ? O B HOH 1031 ? ? 2.05 
25 1 O    A HOH 656  ? ? O B HOH 773  ? ? 2.06 
26 1 O    B HOH 403  ? ? O B HOH 737  ? ? 2.06 
27 1 O    B HOH 665  ? ? O B HOH 859  ? ? 2.07 
28 1 O    A HOH 824  ? ? O A HOH 1058 ? ? 2.07 
29 1 O    B HOH 912  ? ? O B HOH 987  ? ? 2.09 
30 1 O    B HOH 420  ? ? O B HOH 729  ? ? 2.09 
31 1 O    B HOH 862  ? ? O B HOH 879  ? ? 2.09 
32 1 O    A HOH 409  ? ? O A HOH 810  ? ? 2.10 
33 1 O    A HOH 852  ? ? O B HOH 897  ? ? 2.10 
34 1 O    A HOH 1007 ? ? O A HOH 1061 ? ? 2.12 
35 1 O    A HOH 778  ? ? O A HOH 812  ? ? 2.12 
36 1 O    A HOH 971  ? ? O A HOH 1068 ? ? 2.15 
37 1 O    B HOH 429  ? ? O B HOH 506  ? ? 2.15 
38 1 O    A HOH 761  ? ? O A HOH 968  ? ? 2.15 
39 1 O    B HOH 630  ? ? O B HOH 1018 ? ? 2.16 
40 1 O    A HOH 937  ? ? O A HOH 975  ? ? 2.16 
41 1 O    B HOH 653  ? ? O B HOH 931  ? ? 2.17 
42 1 O    B HOH 885  ? ? O B HOH 1092 ? ? 2.17 
43 1 O    A HOH 609  ? ? O A HOH 919  ? ? 2.17 
44 1 O    B HOH 413  ? ? O B HOH 950  ? ? 2.17 
45 1 O    A HOH 434  ? ? O A HOH 822  ? ? 2.18 
46 1 O    A HOH 536  ? ? O B HOH 538  ? ? 2.18 
47 1 O    A HOH 939  ? ? O A HOH 1026 ? ? 2.19 
48 1 O    B HOH 682  ? ? O B HOH 877  ? ? 2.19 
49 1 NH2  B ARG 308  ? ? O B HOH 403  ? ? 2.19 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O A HOH 793 ? ? 1_555 O B HOH 781 ? ? 1_554 2.05 
2 1 O A HOH 873 ? ? 1_555 O B HOH 697 ? ? 1_454 2.14 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN A 108 ? ? 81.71   10.64  
2 1 ALA A 173 ? ? 81.38   14.66  
3 1 ILE A 219 ? ? -134.78 -40.78 
4 1 LEU A 351 ? ? -104.04 -65.51 
5 1 ALA B 173 ? ? 80.83   16.38  
6 1 ILE B 219 ? ? -134.70 -41.51 
7 1 LEU B 351 ? ? -106.44 -65.83 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1  1 O ? A HOH 1082 ? 5.85 .    
2  1 O ? A HOH 1083 ? 6.07 .    
3  1 O ? A HOH 1084 ? 6.12 .    
4  1 O ? A HOH 1085 ? .    6.17 
5  1 O ? A HOH 1086 ? 6.23 .    
6  1 O ? A HOH 1087 ? 6.39 .    
7  1 O ? A HOH 1091 ? 6.70 .    
8  1 O ? A HOH 1092 ? .    6.59 
9  1 O ? B HOH 1097 ? 5.92 .    
10 1 O ? B HOH 1098 ? 6.08 .    
11 1 O ? B HOH 1099 ? 6.09 .    
12 1 O ? B HOH 1100 ? 6.17 .    
13 1 O ? B HOH 1104 ? 6.82 .    
14 1 O ? B HOH 1105 ? 6.93 .    
15 1 O ? B HOH 1106 ? 6.95 .    
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET -33 ? A MET 1   
2   1 Y 1 A GLY -32 ? A GLY 2   
3   1 Y 1 A SER -31 ? A SER 3   
4   1 Y 1 A SER -30 ? A SER 4   
5   1 Y 1 A HIS -29 ? A HIS 5   
6   1 Y 1 A HIS -28 ? A HIS 6   
7   1 Y 1 A HIS -27 ? A HIS 7   
8   1 Y 1 A HIS -26 ? A HIS 8   
9   1 Y 1 A HIS -25 ? A HIS 9   
10  1 Y 1 A HIS -24 ? A HIS 10  
11  1 Y 1 A SER -23 ? A SER 11  
12  1 Y 1 A SER -22 ? A SER 12  
13  1 Y 1 A GLY -21 ? A GLY 13  
14  1 Y 1 A LEU -20 ? A LEU 14  
15  1 Y 1 A VAL -19 ? A VAL 15  
16  1 Y 1 A PRO -18 ? A PRO 16  
17  1 Y 1 A ARG -17 ? A ARG 17  
18  1 Y 1 A GLY -16 ? A GLY 18  
19  1 Y 1 A SER -15 ? A SER 19  
20  1 Y 1 A HIS -14 ? A HIS 20  
21  1 Y 1 A MET -13 ? A MET 21  
22  1 Y 1 A ALA -12 ? A ALA 22  
23  1 Y 1 A SER -11 ? A SER 23  
24  1 Y 1 A MET -10 ? A MET 24  
25  1 Y 1 A THR -9  ? A THR 25  
26  1 Y 1 A GLY -8  ? A GLY 26  
27  1 Y 1 A GLY -7  ? A GLY 27  
28  1 Y 1 A GLN -6  ? A GLN 28  
29  1 Y 1 A GLN -5  ? A GLN 29  
30  1 Y 1 A MET -4  ? A MET 30  
31  1 Y 1 A GLY -3  ? A GLY 31  
32  1 Y 1 A ARG -2  ? A ARG 32  
33  1 Y 1 A GLY -1  ? A GLY 33  
34  1 Y 1 A SER 0   ? A SER 34  
35  1 Y 1 A SER 1   ? A SER 35  
36  1 Y 1 A THR 2   ? A THR 36  
37  1 Y 1 A LYS 3   ? A LYS 37  
38  1 Y 1 A ASN 4   ? A ASN 38  
39  1 Y 1 A GLY 5   ? A GLY 39  
40  1 Y 1 A ILE 6   ? A ILE 40  
41  1 Y 1 A ILE 7   ? A ILE 41  
42  1 Y 1 A GLU 8   ? A GLU 42  
43  1 Y 1 A LEU 9   ? A LEU 43  
44  1 Y 1 A GLU 10  ? A GLU 44  
45  1 Y 1 A GLN 11  ? A GLN 45  
46  1 Y 1 A GLU 12  ? A GLU 46  
47  1 Y 1 A THR 13  ? A THR 47  
48  1 Y 1 A GLU 14  ? A GLU 48  
49  1 Y 1 A GLU 15  ? A GLU 49  
50  1 Y 1 A GLU 16  ? A GLU 50  
51  1 Y 1 A GLU 389 ? A GLU 423 
52  1 Y 1 B MET -33 ? B MET 1   
53  1 Y 1 B GLY -32 ? B GLY 2   
54  1 Y 1 B SER -31 ? B SER 3   
55  1 Y 1 B SER -30 ? B SER 4   
56  1 Y 1 B HIS -29 ? B HIS 5   
57  1 Y 1 B HIS -28 ? B HIS 6   
58  1 Y 1 B HIS -27 ? B HIS 7   
59  1 Y 1 B HIS -26 ? B HIS 8   
60  1 Y 1 B HIS -25 ? B HIS 9   
61  1 Y 1 B HIS -24 ? B HIS 10  
62  1 Y 1 B SER -23 ? B SER 11  
63  1 Y 1 B SER -22 ? B SER 12  
64  1 Y 1 B GLY -21 ? B GLY 13  
65  1 Y 1 B LEU -20 ? B LEU 14  
66  1 Y 1 B VAL -19 ? B VAL 15  
67  1 Y 1 B PRO -18 ? B PRO 16  
68  1 Y 1 B ARG -17 ? B ARG 17  
69  1 Y 1 B GLY -16 ? B GLY 18  
70  1 Y 1 B SER -15 ? B SER 19  
71  1 Y 1 B HIS -14 ? B HIS 20  
72  1 Y 1 B MET -13 ? B MET 21  
73  1 Y 1 B ALA -12 ? B ALA 22  
74  1 Y 1 B SER -11 ? B SER 23  
75  1 Y 1 B MET -10 ? B MET 24  
76  1 Y 1 B THR -9  ? B THR 25  
77  1 Y 1 B GLY -8  ? B GLY 26  
78  1 Y 1 B GLY -7  ? B GLY 27  
79  1 Y 1 B GLN -6  ? B GLN 28  
80  1 Y 1 B GLN -5  ? B GLN 29  
81  1 Y 1 B MET -4  ? B MET 30  
82  1 Y 1 B GLY -3  ? B GLY 31  
83  1 Y 1 B ARG -2  ? B ARG 32  
84  1 Y 1 B GLY -1  ? B GLY 33  
85  1 Y 1 B SER 0   ? B SER 34  
86  1 Y 1 B SER 1   ? B SER 35  
87  1 Y 1 B THR 2   ? B THR 36  
88  1 Y 1 B LYS 3   ? B LYS 37  
89  1 Y 1 B ASN 4   ? B ASN 38  
90  1 Y 1 B GLY 5   ? B GLY 39  
91  1 Y 1 B ILE 6   ? B ILE 40  
92  1 Y 1 B ILE 7   ? B ILE 41  
93  1 Y 1 B GLU 8   ? B GLU 42  
94  1 Y 1 B LEU 9   ? B LEU 43  
95  1 Y 1 B GLU 10  ? B GLU 44  
96  1 Y 1 B GLN 11  ? B GLN 45  
97  1 Y 1 B GLU 12  ? B GLU 46  
98  1 Y 1 B THR 13  ? B THR 47  
99  1 Y 1 B GLU 14  ? B GLU 48  
100 1 Y 1 B GLU 15  ? B GLU 49  
101 1 Y 1 B GLU 16  ? B GLU 50  
102 1 Y 1 B LEU 17  ? B LEU 51  
103 1 Y 1 B GLU 18  ? B GLU 52  
104 1 Y 1 B GLN 19  ? B GLN 53  
105 1 Y 1 B ASN 20  ? B ASN 54  
106 1 Y 1 B GLN 21  ? B GLN 55  
107 1 Y 1 B GLU 22  ? B GLU 56  
108 1 Y 1 B GLU 389 ? B GLU 423 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
FUC C1   C N R 88  
FUC C2   C N S 89  
FUC C3   C N R 90  
FUC C4   C N S 91  
FUC C5   C N S 92  
FUC C6   C N N 93  
FUC O1   O N N 94  
FUC O2   O N N 95  
FUC O3   O N N 96  
FUC O4   O N N 97  
FUC O5   O N N 98  
FUC H1   H N N 99  
FUC H2   H N N 100 
FUC H3   H N N 101 
FUC H4   H N N 102 
FUC H5   H N N 103 
FUC H61  H N N 104 
FUC H62  H N N 105 
FUC H63  H N N 106 
FUC HO1  H N N 107 
FUC HO2  H N N 108 
FUC HO3  H N N 109 
FUC HO4  H N N 110 
GLN N    N N N 111 
GLN CA   C N S 112 
GLN C    C N N 113 
GLN O    O N N 114 
GLN CB   C N N 115 
GLN CG   C N N 116 
GLN CD   C N N 117 
GLN OE1  O N N 118 
GLN NE2  N N N 119 
GLN OXT  O N N 120 
GLN H    H N N 121 
GLN H2   H N N 122 
GLN HA   H N N 123 
GLN HB2  H N N 124 
GLN HB3  H N N 125 
GLN HG2  H N N 126 
GLN HG3  H N N 127 
GLN HE21 H N N 128 
GLN HE22 H N N 129 
GLN HXT  H N N 130 
GLU N    N N N 131 
GLU CA   C N S 132 
GLU C    C N N 133 
GLU O    O N N 134 
GLU CB   C N N 135 
GLU CG   C N N 136 
GLU CD   C N N 137 
GLU OE1  O N N 138 
GLU OE2  O N N 139 
GLU OXT  O N N 140 
GLU H    H N N 141 
GLU H2   H N N 142 
GLU HA   H N N 143 
GLU HB2  H N N 144 
GLU HB3  H N N 145 
GLU HG2  H N N 146 
GLU HG3  H N N 147 
GLU HE2  H N N 148 
GLU HXT  H N N 149 
GLY N    N N N 150 
GLY CA   C N N 151 
GLY C    C N N 152 
GLY O    O N N 153 
GLY OXT  O N N 154 
GLY H    H N N 155 
GLY H2   H N N 156 
GLY HA2  H N N 157 
GLY HA3  H N N 158 
GLY HXT  H N N 159 
HIS N    N N N 160 
HIS CA   C N S 161 
HIS C    C N N 162 
HIS O    O N N 163 
HIS CB   C N N 164 
HIS CG   C Y N 165 
HIS ND1  N Y N 166 
HIS CD2  C Y N 167 
HIS CE1  C Y N 168 
HIS NE2  N Y N 169 
HIS OXT  O N N 170 
HIS H    H N N 171 
HIS H2   H N N 172 
HIS HA   H N N 173 
HIS HB2  H N N 174 
HIS HB3  H N N 175 
HIS HD1  H N N 176 
HIS HD2  H N N 177 
HIS HE1  H N N 178 
HIS HE2  H N N 179 
HIS HXT  H N N 180 
HOH O    O N N 181 
HOH H1   H N N 182 
HOH H2   H N N 183 
ILE N    N N N 184 
ILE CA   C N S 185 
ILE C    C N N 186 
ILE O    O N N 187 
ILE CB   C N S 188 
ILE CG1  C N N 189 
ILE CG2  C N N 190 
ILE CD1  C N N 191 
ILE OXT  O N N 192 
ILE H    H N N 193 
ILE H2   H N N 194 
ILE HA   H N N 195 
ILE HB   H N N 196 
ILE HG12 H N N 197 
ILE HG13 H N N 198 
ILE HG21 H N N 199 
ILE HG22 H N N 200 
ILE HG23 H N N 201 
ILE HD11 H N N 202 
ILE HD12 H N N 203 
ILE HD13 H N N 204 
ILE HXT  H N N 205 
LEU N    N N N 206 
LEU CA   C N S 207 
LEU C    C N N 208 
LEU O    O N N 209 
LEU CB   C N N 210 
LEU CG   C N N 211 
LEU CD1  C N N 212 
LEU CD2  C N N 213 
LEU OXT  O N N 214 
LEU H    H N N 215 
LEU H2   H N N 216 
LEU HA   H N N 217 
LEU HB2  H N N 218 
LEU HB3  H N N 219 
LEU HG   H N N 220 
LEU HD11 H N N 221 
LEU HD12 H N N 222 
LEU HD13 H N N 223 
LEU HD21 H N N 224 
LEU HD22 H N N 225 
LEU HD23 H N N 226 
LEU HXT  H N N 227 
LYS N    N N N 228 
LYS CA   C N S 229 
LYS C    C N N 230 
LYS O    O N N 231 
LYS CB   C N N 232 
LYS CG   C N N 233 
LYS CD   C N N 234 
LYS CE   C N N 235 
LYS NZ   N N N 236 
LYS OXT  O N N 237 
LYS H    H N N 238 
LYS H2   H N N 239 
LYS HA   H N N 240 
LYS HB2  H N N 241 
LYS HB3  H N N 242 
LYS HG2  H N N 243 
LYS HG3  H N N 244 
LYS HD2  H N N 245 
LYS HD3  H N N 246 
LYS HE2  H N N 247 
LYS HE3  H N N 248 
LYS HZ1  H N N 249 
LYS HZ2  H N N 250 
LYS HZ3  H N N 251 
LYS HXT  H N N 252 
MET N    N N N 253 
MET CA   C N S 254 
MET C    C N N 255 
MET O    O N N 256 
MET CB   C N N 257 
MET CG   C N N 258 
MET SD   S N N 259 
MET CE   C N N 260 
MET OXT  O N N 261 
MET H    H N N 262 
MET H2   H N N 263 
MET HA   H N N 264 
MET HB2  H N N 265 
MET HB3  H N N 266 
MET HG2  H N N 267 
MET HG3  H N N 268 
MET HE1  H N N 269 
MET HE2  H N N 270 
MET HE3  H N N 271 
MET HXT  H N N 272 
PHE N    N N N 273 
PHE CA   C N S 274 
PHE C    C N N 275 
PHE O    O N N 276 
PHE CB   C N N 277 
PHE CG   C Y N 278 
PHE CD1  C Y N 279 
PHE CD2  C Y N 280 
PHE CE1  C Y N 281 
PHE CE2  C Y N 282 
PHE CZ   C Y N 283 
PHE OXT  O N N 284 
PHE H    H N N 285 
PHE H2   H N N 286 
PHE HA   H N N 287 
PHE HB2  H N N 288 
PHE HB3  H N N 289 
PHE HD1  H N N 290 
PHE HD2  H N N 291 
PHE HE1  H N N 292 
PHE HE2  H N N 293 
PHE HZ   H N N 294 
PHE HXT  H N N 295 
PRO N    N N N 296 
PRO CA   C N S 297 
PRO C    C N N 298 
PRO O    O N N 299 
PRO CB   C N N 300 
PRO CG   C N N 301 
PRO CD   C N N 302 
PRO OXT  O N N 303 
PRO H    H N N 304 
PRO HA   H N N 305 
PRO HB2  H N N 306 
PRO HB3  H N N 307 
PRO HG2  H N N 308 
PRO HG3  H N N 309 
PRO HD2  H N N 310 
PRO HD3  H N N 311 
PRO HXT  H N N 312 
SER N    N N N 313 
SER CA   C N S 314 
SER C    C N N 315 
SER O    O N N 316 
SER CB   C N N 317 
SER OG   O N N 318 
SER OXT  O N N 319 
SER H    H N N 320 
SER H2   H N N 321 
SER HA   H N N 322 
SER HB2  H N N 323 
SER HB3  H N N 324 
SER HG   H N N 325 
SER HXT  H N N 326 
THR N    N N N 327 
THR CA   C N S 328 
THR C    C N N 329 
THR O    O N N 330 
THR CB   C N R 331 
THR OG1  O N N 332 
THR CG2  C N N 333 
THR OXT  O N N 334 
THR H    H N N 335 
THR H2   H N N 336 
THR HA   H N N 337 
THR HB   H N N 338 
THR HG1  H N N 339 
THR HG21 H N N 340 
THR HG22 H N N 341 
THR HG23 H N N 342 
THR HXT  H N N 343 
TRP N    N N N 344 
TRP CA   C N S 345 
TRP C    C N N 346 
TRP O    O N N 347 
TRP CB   C N N 348 
TRP CG   C Y N 349 
TRP CD1  C Y N 350 
TRP CD2  C Y N 351 
TRP NE1  N Y N 352 
TRP CE2  C Y N 353 
TRP CE3  C Y N 354 
TRP CZ2  C Y N 355 
TRP CZ3  C Y N 356 
TRP CH2  C Y N 357 
TRP OXT  O N N 358 
TRP H    H N N 359 
TRP H2   H N N 360 
TRP HA   H N N 361 
TRP HB2  H N N 362 
TRP HB3  H N N 363 
TRP HD1  H N N 364 
TRP HE1  H N N 365 
TRP HE3  H N N 366 
TRP HZ2  H N N 367 
TRP HZ3  H N N 368 
TRP HH2  H N N 369 
TRP HXT  H N N 370 
TYR N    N N N 371 
TYR CA   C N S 372 
TYR C    C N N 373 
TYR O    O N N 374 
TYR CB   C N N 375 
TYR CG   C Y N 376 
TYR CD1  C Y N 377 
TYR CD2  C Y N 378 
TYR CE1  C Y N 379 
TYR CE2  C Y N 380 
TYR CZ   C Y N 381 
TYR OH   O N N 382 
TYR OXT  O N N 383 
TYR H    H N N 384 
TYR H2   H N N 385 
TYR HA   H N N 386 
TYR HB2  H N N 387 
TYR HB3  H N N 388 
TYR HD1  H N N 389 
TYR HD2  H N N 390 
TYR HE1  H N N 391 
TYR HE2  H N N 392 
TYR HH   H N N 393 
TYR HXT  H N N 394 
VAL N    N N N 395 
VAL CA   C N S 396 
VAL C    C N N 397 
VAL O    O N N 398 
VAL CB   C N N 399 
VAL CG1  C N N 400 
VAL CG2  C N N 401 
VAL OXT  O N N 402 
VAL H    H N N 403 
VAL H2   H N N 404 
VAL HA   H N N 405 
VAL HB   H N N 406 
VAL HG11 H N N 407 
VAL HG12 H N N 408 
VAL HG13 H N N 409 
VAL HG21 H N N 410 
VAL HG22 H N N 411 
VAL HG23 H N N 412 
VAL HXT  H N N 413 
X2Y C5   C N S 414 
X2Y C4   C N S 415 
X2Y C3   C N R 416 
X2Y C2   C N S 417 
X2Y C1   C N R 418 
X2Y O5   O N N 419 
X2Y C6   C N N 420 
X2Y O3   O N N 421 
X2Y S1   S N N 422 
X2Y O6   O N N 423 
X2Y O7   O N N 424 
X2Y O8   O N N 425 
X2Y O2   O N N 426 
X2Y S2   S N N 427 
X2Y O9   O N N 428 
X2Y O10  O N N 429 
X2Y O11  O N N 430 
X2Y O4   O N N 431 
X2Y H5   H N N 432 
X2Y H4   H N N 433 
X2Y H3   H N N 434 
X2Y H2   H N N 435 
X2Y H1   H N N 436 
X2Y H61  H N N 437 
X2Y H63  H N N 438 
X2Y H62  H N N 439 
X2Y HO3  H N N 440 
X2Y O1   O N N 441 
X2Y H9   H N N 442 
X2Y H11  H N N 443 
X2Y HO1  H N N 444 
X6Y C5   C N S 445 
X6Y C6   C N N 446 
X6Y C2   C N S 447 
X6Y C4   C N S 448 
X6Y C3   C N R 449 
X6Y C1   C N R 450 
X6Y O5   O N N 451 
X6Y O4   O N N 452 
X6Y O1   O N N 453 
X6Y O3   O N N 454 
X6Y S1   S N N 455 
X6Y O6   O N N 456 
X6Y O7   O N N 457 
X6Y O8   O N N 458 
X6Y O2   O N N 459 
X6Y H5   H N N 460 
X6Y H61  H N N 461 
X6Y H63  H N N 462 
X6Y H62  H N N 463 
X6Y H2   H N N 464 
X6Y H4   H N N 465 
X6Y H3   H N N 466 
X6Y H1   H N N 467 
X6Y HO4  H N N 468 
X6Y HO1  H N N 469 
X6Y HO3  H N N 470 
X6Y H10  H N N 471 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
FUC C1  C2   sing N N 83  
FUC C1  O1   sing N N 84  
FUC C1  O5   sing N N 85  
FUC C1  H1   sing N N 86  
FUC C2  C3   sing N N 87  
FUC C2  O2   sing N N 88  
FUC C2  H2   sing N N 89  
FUC C3  C4   sing N N 90  
FUC C3  O3   sing N N 91  
FUC C3  H3   sing N N 92  
FUC C4  C5   sing N N 93  
FUC C4  O4   sing N N 94  
FUC C4  H4   sing N N 95  
FUC C5  C6   sing N N 96  
FUC C5  O5   sing N N 97  
FUC C5  H5   sing N N 98  
FUC C6  H61  sing N N 99  
FUC C6  H62  sing N N 100 
FUC C6  H63  sing N N 101 
FUC O1  HO1  sing N N 102 
FUC O2  HO2  sing N N 103 
FUC O3  HO3  sing N N 104 
FUC O4  HO4  sing N N 105 
GLN N   CA   sing N N 106 
GLN N   H    sing N N 107 
GLN N   H2   sing N N 108 
GLN CA  C    sing N N 109 
GLN CA  CB   sing N N 110 
GLN CA  HA   sing N N 111 
GLN C   O    doub N N 112 
GLN C   OXT  sing N N 113 
GLN CB  CG   sing N N 114 
GLN CB  HB2  sing N N 115 
GLN CB  HB3  sing N N 116 
GLN CG  CD   sing N N 117 
GLN CG  HG2  sing N N 118 
GLN CG  HG3  sing N N 119 
GLN CD  OE1  doub N N 120 
GLN CD  NE2  sing N N 121 
GLN NE2 HE21 sing N N 122 
GLN NE2 HE22 sing N N 123 
GLN OXT HXT  sing N N 124 
GLU N   CA   sing N N 125 
GLU N   H    sing N N 126 
GLU N   H2   sing N N 127 
GLU CA  C    sing N N 128 
GLU CA  CB   sing N N 129 
GLU CA  HA   sing N N 130 
GLU C   O    doub N N 131 
GLU C   OXT  sing N N 132 
GLU CB  CG   sing N N 133 
GLU CB  HB2  sing N N 134 
GLU CB  HB3  sing N N 135 
GLU CG  CD   sing N N 136 
GLU CG  HG2  sing N N 137 
GLU CG  HG3  sing N N 138 
GLU CD  OE1  doub N N 139 
GLU CD  OE2  sing N N 140 
GLU OE2 HE2  sing N N 141 
GLU OXT HXT  sing N N 142 
GLY N   CA   sing N N 143 
GLY N   H    sing N N 144 
GLY N   H2   sing N N 145 
GLY CA  C    sing N N 146 
GLY CA  HA2  sing N N 147 
GLY CA  HA3  sing N N 148 
GLY C   O    doub N N 149 
GLY C   OXT  sing N N 150 
GLY OXT HXT  sing N N 151 
HIS N   CA   sing N N 152 
HIS N   H    sing N N 153 
HIS N   H2   sing N N 154 
HIS CA  C    sing N N 155 
HIS CA  CB   sing N N 156 
HIS CA  HA   sing N N 157 
HIS C   O    doub N N 158 
HIS C   OXT  sing N N 159 
HIS CB  CG   sing N N 160 
HIS CB  HB2  sing N N 161 
HIS CB  HB3  sing N N 162 
HIS CG  ND1  sing Y N 163 
HIS CG  CD2  doub Y N 164 
HIS ND1 CE1  doub Y N 165 
HIS ND1 HD1  sing N N 166 
HIS CD2 NE2  sing Y N 167 
HIS CD2 HD2  sing N N 168 
HIS CE1 NE2  sing Y N 169 
HIS CE1 HE1  sing N N 170 
HIS NE2 HE2  sing N N 171 
HIS OXT HXT  sing N N 172 
HOH O   H1   sing N N 173 
HOH O   H2   sing N N 174 
ILE N   CA   sing N N 175 
ILE N   H    sing N N 176 
ILE N   H2   sing N N 177 
ILE CA  C    sing N N 178 
ILE CA  CB   sing N N 179 
ILE CA  HA   sing N N 180 
ILE C   O    doub N N 181 
ILE C   OXT  sing N N 182 
ILE CB  CG1  sing N N 183 
ILE CB  CG2  sing N N 184 
ILE CB  HB   sing N N 185 
ILE CG1 CD1  sing N N 186 
ILE CG1 HG12 sing N N 187 
ILE CG1 HG13 sing N N 188 
ILE CG2 HG21 sing N N 189 
ILE CG2 HG22 sing N N 190 
ILE CG2 HG23 sing N N 191 
ILE CD1 HD11 sing N N 192 
ILE CD1 HD12 sing N N 193 
ILE CD1 HD13 sing N N 194 
ILE OXT HXT  sing N N 195 
LEU N   CA   sing N N 196 
LEU N   H    sing N N 197 
LEU N   H2   sing N N 198 
LEU CA  C    sing N N 199 
LEU CA  CB   sing N N 200 
LEU CA  HA   sing N N 201 
LEU C   O    doub N N 202 
LEU C   OXT  sing N N 203 
LEU CB  CG   sing N N 204 
LEU CB  HB2  sing N N 205 
LEU CB  HB3  sing N N 206 
LEU CG  CD1  sing N N 207 
LEU CG  CD2  sing N N 208 
LEU CG  HG   sing N N 209 
LEU CD1 HD11 sing N N 210 
LEU CD1 HD12 sing N N 211 
LEU CD1 HD13 sing N N 212 
LEU CD2 HD21 sing N N 213 
LEU CD2 HD22 sing N N 214 
LEU CD2 HD23 sing N N 215 
LEU OXT HXT  sing N N 216 
LYS N   CA   sing N N 217 
LYS N   H    sing N N 218 
LYS N   H2   sing N N 219 
LYS CA  C    sing N N 220 
LYS CA  CB   sing N N 221 
LYS CA  HA   sing N N 222 
LYS C   O    doub N N 223 
LYS C   OXT  sing N N 224 
LYS CB  CG   sing N N 225 
LYS CB  HB2  sing N N 226 
LYS CB  HB3  sing N N 227 
LYS CG  CD   sing N N 228 
LYS CG  HG2  sing N N 229 
LYS CG  HG3  sing N N 230 
LYS CD  CE   sing N N 231 
LYS CD  HD2  sing N N 232 
LYS CD  HD3  sing N N 233 
LYS CE  NZ   sing N N 234 
LYS CE  HE2  sing N N 235 
LYS CE  HE3  sing N N 236 
LYS NZ  HZ1  sing N N 237 
LYS NZ  HZ2  sing N N 238 
LYS NZ  HZ3  sing N N 239 
LYS OXT HXT  sing N N 240 
MET N   CA   sing N N 241 
MET N   H    sing N N 242 
MET N   H2   sing N N 243 
MET CA  C    sing N N 244 
MET CA  CB   sing N N 245 
MET CA  HA   sing N N 246 
MET C   O    doub N N 247 
MET C   OXT  sing N N 248 
MET CB  CG   sing N N 249 
MET CB  HB2  sing N N 250 
MET CB  HB3  sing N N 251 
MET CG  SD   sing N N 252 
MET CG  HG2  sing N N 253 
MET CG  HG3  sing N N 254 
MET SD  CE   sing N N 255 
MET CE  HE1  sing N N 256 
MET CE  HE2  sing N N 257 
MET CE  HE3  sing N N 258 
MET OXT HXT  sing N N 259 
PHE N   CA   sing N N 260 
PHE N   H    sing N N 261 
PHE N   H2   sing N N 262 
PHE CA  C    sing N N 263 
PHE CA  CB   sing N N 264 
PHE CA  HA   sing N N 265 
PHE C   O    doub N N 266 
PHE C   OXT  sing N N 267 
PHE CB  CG   sing N N 268 
PHE CB  HB2  sing N N 269 
PHE CB  HB3  sing N N 270 
PHE CG  CD1  doub Y N 271 
PHE CG  CD2  sing Y N 272 
PHE CD1 CE1  sing Y N 273 
PHE CD1 HD1  sing N N 274 
PHE CD2 CE2  doub Y N 275 
PHE CD2 HD2  sing N N 276 
PHE CE1 CZ   doub Y N 277 
PHE CE1 HE1  sing N N 278 
PHE CE2 CZ   sing Y N 279 
PHE CE2 HE2  sing N N 280 
PHE CZ  HZ   sing N N 281 
PHE OXT HXT  sing N N 282 
PRO N   CA   sing N N 283 
PRO N   CD   sing N N 284 
PRO N   H    sing N N 285 
PRO CA  C    sing N N 286 
PRO CA  CB   sing N N 287 
PRO CA  HA   sing N N 288 
PRO C   O    doub N N 289 
PRO C   OXT  sing N N 290 
PRO CB  CG   sing N N 291 
PRO CB  HB2  sing N N 292 
PRO CB  HB3  sing N N 293 
PRO CG  CD   sing N N 294 
PRO CG  HG2  sing N N 295 
PRO CG  HG3  sing N N 296 
PRO CD  HD2  sing N N 297 
PRO CD  HD3  sing N N 298 
PRO OXT HXT  sing N N 299 
SER N   CA   sing N N 300 
SER N   H    sing N N 301 
SER N   H2   sing N N 302 
SER CA  C    sing N N 303 
SER CA  CB   sing N N 304 
SER CA  HA   sing N N 305 
SER C   O    doub N N 306 
SER C   OXT  sing N N 307 
SER CB  OG   sing N N 308 
SER CB  HB2  sing N N 309 
SER CB  HB3  sing N N 310 
SER OG  HG   sing N N 311 
SER OXT HXT  sing N N 312 
THR N   CA   sing N N 313 
THR N   H    sing N N 314 
THR N   H2   sing N N 315 
THR CA  C    sing N N 316 
THR CA  CB   sing N N 317 
THR CA  HA   sing N N 318 
THR C   O    doub N N 319 
THR C   OXT  sing N N 320 
THR CB  OG1  sing N N 321 
THR CB  CG2  sing N N 322 
THR CB  HB   sing N N 323 
THR OG1 HG1  sing N N 324 
THR CG2 HG21 sing N N 325 
THR CG2 HG22 sing N N 326 
THR CG2 HG23 sing N N 327 
THR OXT HXT  sing N N 328 
TRP N   CA   sing N N 329 
TRP N   H    sing N N 330 
TRP N   H2   sing N N 331 
TRP CA  C    sing N N 332 
TRP CA  CB   sing N N 333 
TRP CA  HA   sing N N 334 
TRP C   O    doub N N 335 
TRP C   OXT  sing N N 336 
TRP CB  CG   sing N N 337 
TRP CB  HB2  sing N N 338 
TRP CB  HB3  sing N N 339 
TRP CG  CD1  doub Y N 340 
TRP CG  CD2  sing Y N 341 
TRP CD1 NE1  sing Y N 342 
TRP CD1 HD1  sing N N 343 
TRP CD2 CE2  doub Y N 344 
TRP CD2 CE3  sing Y N 345 
TRP NE1 CE2  sing Y N 346 
TRP NE1 HE1  sing N N 347 
TRP CE2 CZ2  sing Y N 348 
TRP CE3 CZ3  doub Y N 349 
TRP CE3 HE3  sing N N 350 
TRP CZ2 CH2  doub Y N 351 
TRP CZ2 HZ2  sing N N 352 
TRP CZ3 CH2  sing Y N 353 
TRP CZ3 HZ3  sing N N 354 
TRP CH2 HH2  sing N N 355 
TRP OXT HXT  sing N N 356 
TYR N   CA   sing N N 357 
TYR N   H    sing N N 358 
TYR N   H2   sing N N 359 
TYR CA  C    sing N N 360 
TYR CA  CB   sing N N 361 
TYR CA  HA   sing N N 362 
TYR C   O    doub N N 363 
TYR C   OXT  sing N N 364 
TYR CB  CG   sing N N 365 
TYR CB  HB2  sing N N 366 
TYR CB  HB3  sing N N 367 
TYR CG  CD1  doub Y N 368 
TYR CG  CD2  sing Y N 369 
TYR CD1 CE1  sing Y N 370 
TYR CD1 HD1  sing N N 371 
TYR CD2 CE2  doub Y N 372 
TYR CD2 HD2  sing N N 373 
TYR CE1 CZ   doub Y N 374 
TYR CE1 HE1  sing N N 375 
TYR CE2 CZ   sing Y N 376 
TYR CE2 HE2  sing N N 377 
TYR CZ  OH   sing N N 378 
TYR OH  HH   sing N N 379 
TYR OXT HXT  sing N N 380 
VAL N   CA   sing N N 381 
VAL N   H    sing N N 382 
VAL N   H2   sing N N 383 
VAL CA  C    sing N N 384 
VAL CA  CB   sing N N 385 
VAL CA  HA   sing N N 386 
VAL C   O    doub N N 387 
VAL C   OXT  sing N N 388 
VAL CB  CG1  sing N N 389 
VAL CB  CG2  sing N N 390 
VAL CB  HB   sing N N 391 
VAL CG1 HG11 sing N N 392 
VAL CG1 HG12 sing N N 393 
VAL CG1 HG13 sing N N 394 
VAL CG2 HG21 sing N N 395 
VAL CG2 HG22 sing N N 396 
VAL CG2 HG23 sing N N 397 
VAL OXT HXT  sing N N 398 
X2Y O7  S1   doub N N 399 
X2Y O8  S1   doub N N 400 
X2Y O6  S1   sing N N 401 
X2Y S1  O2   sing N N 402 
X2Y O2  C2   sing N N 403 
X2Y C2  C1   sing N N 404 
X2Y C2  C3   sing N N 405 
X2Y C1  O5   sing N N 406 
X2Y O5  C5   sing N N 407 
X2Y O3  C3   sing N N 408 
X2Y C3  C4   sing N N 409 
X2Y O4  C4   sing N N 410 
X2Y O4  S2   sing N N 411 
X2Y C5  C4   sing N N 412 
X2Y C5  C6   sing N N 413 
X2Y O9  S2   doub N N 414 
X2Y O10 S2   doub N N 415 
X2Y S2  O11  sing N N 416 
X2Y C5  H5   sing N N 417 
X2Y C4  H4   sing N N 418 
X2Y C3  H3   sing N N 419 
X2Y C2  H2   sing N N 420 
X2Y C1  H1   sing N N 421 
X2Y C6  H61  sing N N 422 
X2Y C6  H63  sing N N 423 
X2Y C6  H62  sing N N 424 
X2Y O3  HO3  sing N N 425 
X2Y C1  O1   sing N N 426 
X2Y O6  H9   sing N N 427 
X2Y O11 H11  sing N N 428 
X2Y O1  HO1  sing N N 429 
X6Y O8  S1   doub N N 430 
X6Y O2  S1   sing N N 431 
X6Y O2  C2   sing N N 432 
X6Y S1  O6   doub N N 433 
X6Y S1  O7   sing N N 434 
X6Y O1  C1   sing N N 435 
X6Y O3  C3   sing N N 436 
X6Y C2  C3   sing N N 437 
X6Y C2  C1   sing N N 438 
X6Y C3  C4   sing N N 439 
X6Y C1  O5   sing N N 440 
X6Y C4  C5   sing N N 441 
X6Y C4  O4   sing N N 442 
X6Y O5  C5   sing N N 443 
X6Y C5  C6   sing N N 444 
X6Y C5  H5   sing N N 445 
X6Y C6  H61  sing N N 446 
X6Y C6  H63  sing N N 447 
X6Y C6  H62  sing N N 448 
X6Y C2  H2   sing N N 449 
X6Y C4  H4   sing N N 450 
X6Y C3  H3   sing N N 451 
X6Y C1  H1   sing N N 452 
X6Y O4  HO4  sing N N 453 
X6Y O1  HO1  sing N N 454 
X6Y O3  HO3  sing N N 455 
X6Y O7  H10  sing N N 456 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           U22A20542 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 X6Y 1 n 
2 X6Y 2 n 
2 FUC 3 n 
2 X2Y 4 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9JOG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.018268 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.008004 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007226 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.017367 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N    . LEU A 1 51  ? -31.851 5.160   16.895 1.00 30.00 ?  17   LEU A N    1 
ATOM   2     C CA   . LEU A 1 51  ? -30.421 5.395   17.057 1.00 30.00 ?  17   LEU A CA   1 
ATOM   3     C C    . LEU A 1 51  ? -29.607 4.483   16.146 1.00 30.00 ?  17   LEU A C    1 
ATOM   4     O O    . LEU A 1 51  ? -29.932 3.304   15.929 1.00 30.00 ?  17   LEU A O    1 
ATOM   5     C CB   . LEU A 1 51  ? -30.006 5.190   18.516 1.00 30.00 ?  17   LEU A CB   1 
ATOM   6     C CG   . LEU A 1 51  ? -30.595 6.172   19.532 1.00 30.00 ?  17   LEU A CG   1 
ATOM   7     C CD1  . LEU A 1 51  ? -30.220 5.765   20.949 1.00 30.00 ?  17   LEU A CD1  1 
ATOM   8     C CD2  . LEU A 1 51  ? -30.136 7.591   19.238 1.00 30.00 ?  17   LEU A CD2  1 
ATOM   9     N N    . GLU A 1 52  ? -28.448 5.022   15.780 1.00 23.08 ?  18   GLU A N    1 
ATOM   10    C CA   . GLU A 1 52  ? -27.540 4.347   14.859 1.00 23.93 ?  18   GLU A CA   1 
ATOM   11    C C    . GLU A 1 52  ? -27.175 2.964   15.374 1.00 22.35 ?  18   GLU A C    1 
ATOM   12    O O    . GLU A 1 52  ? -26.745 2.809   16.518 1.00 22.81 ?  18   GLU A O    1 
ATOM   13    C CB   . GLU A 1 52  ? -26.260 5.178   14.705 1.00 23.30 ?  18   GLU A CB   1 
ATOM   14    C CG   . GLU A 1 52  ? -25.225 4.579   13.752 1.00 21.70 ?  18   GLU A CG   1 
ATOM   15    C CD   . GLU A 1 52  ? -25.613 4.727   12.300 1.00 24.33 ?  18   GLU A CD   1 
ATOM   16    O OE1  . GLU A 1 52  ? -26.600 5.449   12.007 1.00 29.05 ?  18   GLU A OE1  1 
ATOM   17    O OE2  . GLU A 1 52  ? -24.947 4.105   11.445 1.00 24.69 ?  18   GLU A OE2  1 
ATOM   18    H H    . GLU A 1 52  ? -28.186 5.806   16.017 1.00 27.69 ?  18   GLU A H    1 
ATOM   19    H HA   . GLU A 1 52  ? -27.973 4.257   13.995 1.00 28.72 ?  18   GLU A HA   1 
ATOM   20    H HB2  . GLU A 1 52  ? -26.499 6.054   14.365 1.00 27.95 ?  18   GLU A HB2  1 
ATOM   21    H HB3  . GLU A 1 52  ? -25.841 5.263   15.576 1.00 27.95 ?  18   GLU A HB3  1 
ATOM   22    H HG2  . GLU A 1 52  ? -24.377 5.030   13.884 1.00 26.03 ?  18   GLU A HG2  1 
ATOM   23    H HG3  . GLU A 1 52  ? -25.131 3.633   13.942 1.00 26.03 ?  18   GLU A HG3  1 
ATOM   24    N N    . GLN A 1 53  ? -27.316 1.958   14.510 1.00 23.65 ?  19   GLN A N    1 
ATOM   25    C CA   . GLN A 1 53  ? -26.970 0.594   14.879 1.00 28.86 ?  19   GLN A CA   1 
ATOM   26    C C    . GLN A 1 53  ? -25.464 0.366   14.758 1.00 20.96 ?  19   GLN A C    1 
ATOM   27    O O    . GLN A 1 53  ? -24.755 1.064   14.026 1.00 21.16 ?  19   GLN A O    1 
ATOM   28    C CB   . GLN A 1 53  ? -27.694 -0.403  13.970 1.00 34.18 ?  19   GLN A CB   1 
ATOM   29    C CG   . GLN A 1 53  ? -29.214 -0.319  14.011 1.00 39.41 ?  19   GLN A CG   1 
ATOM   30    C CD   . GLN A 1 53  ? -29.851 -1.470  14.779 1.00 50.97 ?  19   GLN A CD   1 
ATOM   31    O OE1  . GLN A 1 53  ? -29.630 -1.632  15.981 1.00 51.28 ?  19   GLN A OE1  1 
ATOM   32    H H    . GLN A 1 53  ? -27.610 2.044   13.706 1.00 28.38 ?  19   GLN A H    1 
ATOM   33    H HA   . GLN A 1 53  ? -27.239 0.440   15.799 1.00 34.63 ?  19   GLN A HA   1 
ATOM   34    H HB2  . GLN A 1 53  ? -27.417 -0.242  13.054 1.00 41.01 ?  19   GLN A HB2  1 
ATOM   35    H HB3  . GLN A 1 53  ? -27.444 -1.301  14.239 1.00 41.01 ?  19   GLN A HB3  1 
ATOM   36    H HG2  . GLN A 1 53  ? -29.473 0.510   14.444 1.00 47.29 ?  19   GLN A HG2  1 
ATOM   37    H HG3  . GLN A 1 53  ? -29.556 -0.339  13.103 1.00 47.29 ?  19   GLN A HG3  1 
ATOM   38    N N    . ASN A 1 54  ? -24.982 -0.642  15.478 1.00 23.23 ?  20   ASN A N    1 
ATOM   39    C CA   . ASN A 1 54  ? -23.569 -0.987  15.411 1.00 23.98 ?  20   ASN A CA   1 
ATOM   40    C C    . ASN A 1 54  ? -23.252 -1.685  14.095 1.00 28.70 ?  20   ASN A C    1 
ATOM   41    O O    . ASN A 1 54  ? -24.039 -2.499  13.597 1.00 24.72 ?  20   ASN A O    1 
ATOM   42    C CB   . ASN A 1 54  ? -23.192 -1.918  16.564 1.00 27.13 ?  20   ASN A CB   1 
ATOM   43    C CG   . ASN A 1 54  ? -23.154 -1.210  17.907 1.00 28.06 ?  20   ASN A CG   1 
ATOM   44    O OD1  . ASN A 1 54  ? -22.623 -0.108  18.027 1.00 23.92 ?  20   ASN A OD1  1 
ATOM   45    N ND2  . ASN A 1 54  ? -23.720 -1.845  18.930 1.00 35.94 ?  20   ASN A ND2  1 
ATOM   46    H H    . ASN A 1 54  ? -25.447 -1.136  16.006 1.00 27.88 ?  20   ASN A H    1 
ATOM   47    H HA   . ASN A 1 54  ? -23.044 -0.174  15.477 1.00 28.78 ?  20   ASN A HA   1 
ATOM   48    H HB2  . ASN A 1 54  ? -23.846 -2.632  16.620 1.00 32.55 ?  20   ASN A HB2  1 
ATOM   49    H HB3  . ASN A 1 54  ? -22.311 -2.288  16.395 1.00 32.55 ?  20   ASN A HB3  1 
ATOM   50    H HD21 . ASN A 1 54  ? -24.082 -2.616  18.810 1.00 43.12 ?  20   ASN A HD21 1 
ATOM   51    H HD22 . ASN A 1 54  ? -23.724 -1.485  19.711 1.00 43.12 ?  20   ASN A HD22 1 
ATOM   52    N N    . GLN A 1 55  ? -22.089 -1.365  13.535 1.00 23.92 ?  21   GLN A N    1 
ATOM   53    C CA   . GLN A 1 55  ? -21.603 -2.023  12.335 1.00 22.04 ?  21   GLN A CA   1 
ATOM   54    C C    . GLN A 1 55  ? -21.088 -3.420  12.655 1.00 24.78 ?  21   GLN A C    1 
ATOM   55    O O    . GLN A 1 55  ? -20.630 -3.697  13.767 1.00 24.46 ?  21   GLN A O    1 
ATOM   56    C CB   . GLN A 1 55  ? -20.451 -1.218  11.726 1.00 35.26 ?  21   GLN A CB   1 
ATOM   57    C CG   . GLN A 1 55  ? -20.519 -1.045  10.216 1.00 44.17 ?  21   GLN A CG   1 
ATOM   58    H H    . GLN A 1 55  ? -21.557 -0.761  13.838 1.00 28.70 ?  21   GLN A H    1 
ATOM   59    H HA   . GLN A 1 55  ? -22.330 -2.091  11.695 1.00 26.44 ?  21   GLN A HA   1 
ATOM   60    H HB2  . GLN A 1 55  ? -20.452 -0.332  12.121 1.00 42.31 ?  21   GLN A HB2  1 
ATOM   61    H HB3  . GLN A 1 55  ? -19.618 -1.671  11.930 1.00 42.31 ?  21   GLN A HB3  1 
ATOM   62    H HG2  . GLN A 1 55  ? -20.750 -1.892  9.805  1.00 53.00 ?  21   GLN A HG2  1 
ATOM   63    H HG3  . GLN A 1 55  ? -21.184 -0.372  10.000 1.00 53.00 ?  21   GLN A HG3  1 
ATOM   64    N N    . GLU A 1 56  ? -21.149 -4.302  11.657 1.00 20.32 ?  22   GLU A N    1 
ATOM   65    C CA   . GLU A 1 56  ? -20.474 -5.594  11.772 1.00 25.16 ?  22   GLU A CA   1 
ATOM   66    C C    . GLU A 1 56  ? -19.003 -5.394  12.118 1.00 23.13 ?  22   GLU A C    1 
ATOM   67    O O    . GLU A 1 56  ? -18.328 -4.536  11.546 1.00 21.03 ?  22   GLU A O    1 
ATOM   68    C CB   . GLU A 1 56  ? -20.561 -6.363  10.454 1.00 24.24 ?  22   GLU A CB   1 
ATOM   69    C CG   . GLU A 1 56  ? -20.095 -7.822  10.576 1.00 31.74 ?  22   GLU A CG   1 
ATOM   70    H H    . GLU A 1 56  ? -21.568 -4.179  10.916 1.00 24.38 ?  22   GLU A H    1 
ATOM   71    H HA   . GLU A 1 56  ? -20.909 -6.111  12.469 1.00 30.20 ?  22   GLU A HA   1 
ATOM   72    H HB2  . GLU A 1 56  ? -21.483 -6.368  10.153 1.00 29.09 ?  22   GLU A HB2  1 
ATOM   73    H HB3  . GLU A 1 56  ? -20.000 -5.924  9.796  1.00 29.09 ?  22   GLU A HB3  1 
ATOM   74    H HG2  . GLU A 1 56  ? -19.278 -7.940  10.067 1.00 38.08 ?  22   GLU A HG2  1 
ATOM   75    H HG3  . GLU A 1 56  ? -19.933 -8.026  11.510 1.00 38.08 ?  22   GLU A HG3  1 
ATOM   76    N N    . ILE A 1 57  ? -18.492 -6.210  13.040 1.00 17.20 ?  23   ILE A N    1 
ATOM   77    C CA   . ILE A 1 57  ? -17.153 -5.969  13.574 1.00 15.87 ?  23   ILE A CA   1 
ATOM   78    C C    . ILE A 1 57  ? -16.105 -6.292  12.518 1.00 17.78 ?  23   ILE A C    1 
ATOM   79    O O    . ILE A 1 57  ? -16.102 -7.378  11.924 1.00 25.24 ?  23   ILE A O    1 
ATOM   80    C CB   . ILE A 1 57  ? -16.934 -6.772  14.870 1.00 22.02 ?  23   ILE A CB   1 
ATOM   81    C CG1  . ILE A 1 57  ? -17.788 -6.186  16.003 1.00 25.62 ?  23   ILE A CG1  1 
ATOM   82    C CG2  . ILE A 1 57  ? -15.451 -6.799  15.260 1.00 32.47 ?  23   ILE A CG2  1 
ATOM   83    C CD1  . ILE A 1 57  ? -17.242 -4.914  16.630 1.00 33.63 ?  23   ILE A CD1  1 
ATOM   84    H H    . ILE A 1 57  ? -18.893 -6.897  13.367 1.00 20.64 ?  23   ILE A H    1 
ATOM   85    H HA   . ILE A 1 57  ? -17.067 -5.027  13.790 1.00 19.05 ?  23   ILE A HA   1 
ATOM   86    H HB   . ILE A 1 57  ? -17.213 -7.687  14.711 1.00 26.42 ?  23   ILE A HB   1 
ATOM   87    H HG12 . ILE A 1 57  ? -18.668 -5.980  15.649 1.00 30.75 ?  23   ILE A HG12 1 
ATOM   88    H HG13 . ILE A 1 57  ? -17.861 -6.849  16.707 1.00 30.75 ?  23   ILE A HG13 1 
ATOM   89    H HG21 . ILE A 1 57  ? -15.353 -7.285  16.095 1.00 38.96 ?  23   ILE A HG21 1 
ATOM   90    H HG22 . ILE A 1 57  ? -14.948 -7.243  14.559 1.00 38.96 ?  23   ILE A HG22 1 
ATOM   91    H HG23 . ILE A 1 57  ? -15.136 -5.889  15.369 1.00 38.96 ?  23   ILE A HG23 1 
ATOM   92    H HD11 . ILE A 1 57  ? -17.853 -4.615  17.321 1.00 40.36 ?  23   ILE A HD11 1 
ATOM   93    H HD12 . ILE A 1 57  ? -16.371 -5.101  17.016 1.00 40.36 ?  23   ILE A HD12 1 
ATOM   94    H HD13 . ILE A 1 57  ? -17.160 -4.233  15.943 1.00 40.36 ?  23   ILE A HD13 1 
ATOM   95    N N    . ASP A 1 58  ? -15.205 -5.342  12.281 1.00 16.43 ?  24   ASP A N    1 
ATOM   96    C CA   . ASP A 1 58  ? -14.076 -5.504  11.381 1.00 18.07 ?  24   ASP A CA   1 
ATOM   97    C C    . ASP A 1 58  ? -12.863 -5.007  12.156 1.00 14.97 ?  24   ASP A C    1 
ATOM   98    O O    . ASP A 1 58  ? -12.803 -3.830  12.525 1.00 15.61 ?  24   ASP A O    1 
ATOM   99    C CB   . ASP A 1 58  ? -14.303 -4.680  10.107 1.00 25.25 ?  24   ASP A CB   1 
ATOM   100   C CG   . ASP A 1 58  ? -13.084 -4.648  9.206  1.00 28.71 ?  24   ASP A CG   1 
ATOM   101   O OD1  . ASP A 1 58  ? -12.079 -5.281  9.551  1.00 35.60 ?  24   ASP A OD1  1 
ATOM   102   O OD2  . ASP A 1 58  ? -13.155 -4.001  8.124  1.00 31.32 ?  24   ASP A OD2  1 
ATOM   103   H H    . ASP A 1 58  ? -15.231 -4.564  12.647 1.00 19.71 ?  24   ASP A H    1 
ATOM   104   H HA   . ASP A 1 58  ? -13.937 -6.426  11.115 1.00 21.68 ?  24   ASP A HA   1 
ATOM   105   H HB2  . ASP A 1 58  ? -15.037 -5.068  9.606  1.00 30.30 ?  24   ASP A HB2  1 
ATOM   106   H HB3  . ASP A 1 58  ? -14.517 -3.767  10.355 1.00 30.30 ?  24   ASP A HB3  1 
ATOM   107   N N    . TYR A 1 59  ? -11.934 -5.903  12.450 1.00 13.20 ?  25   TYR A N    1 
ATOM   108   C CA   . TYR A 1 59  ? -10.770 -5.569  13.253 1.00 11.83 ?  25   TYR A CA   1 
ATOM   109   C C    . TYR A 1 59  ? -9.577  -5.117  12.411 1.00 14.50 ?  25   TYR A C    1 
ATOM   110   O O    . TYR A 1 59  ? -8.481  -4.943  12.955 1.00 13.92 ?  25   TYR A O    1 
ATOM   111   C CB   . TYR A 1 59  ? -10.349 -6.775  14.086 1.00 14.14 ?  25   TYR A CB   1 
ATOM   112   C CG   . TYR A 1 59  ? -11.300 -7.277  15.128 1.00 13.95 ?  25   TYR A CG   1 
ATOM   113   C CD1  . TYR A 1 59  ? -11.826 -6.462  16.104 1.00 15.68 ?  25   TYR A CD1  1 
ATOM   114   C CD2  . TYR A 1 59  ? -11.597 -8.630  15.174 1.00 18.13 ?  25   TYR A CD2  1 
ATOM   115   C CE1  . TYR A 1 59  ? -12.676 -6.987  17.099 1.00 17.03 ?  25   TYR A CE1  1 
ATOM   116   C CE2  . TYR A 1 59  ? -12.419 -9.150  16.117 1.00 20.59 ?  25   TYR A CE2  1 
ATOM   117   C CZ   . TYR A 1 59  ? -12.951 -8.340  17.075 1.00 12.00 ?  25   TYR A CZ   1 
ATOM   118   O OH   . TYR A 1 59  ? -13.751 -8.892  18.046 1.00 14.73 ?  25   TYR A OH   1 
ATOM   119   H H    . TYR A 1 59  ? -11.956 -6.723  12.193 1.00 15.83 ?  25   TYR A H    1 
ATOM   120   H HA   . TYR A 1 59  ? -11.016 -4.844  13.849 1.00 14.20 ?  25   TYR A HA   1 
ATOM   121   H HB2  . TYR A 1 59  ? -10.189 -7.513  13.477 1.00 16.96 ?  25   TYR A HB2  1 
ATOM   122   H HB3  . TYR A 1 59  ? -9.528  -6.543  14.548 1.00 16.96 ?  25   TYR A HB3  1 
ATOM   123   H HD1  . TYR A 1 59  ? -11.619 -5.556  16.108 1.00 18.81 ?  25   TYR A HD1  1 
ATOM   124   H HD2  . TYR A 1 59  ? -11.222 -9.197  14.539 1.00 21.75 ?  25   TYR A HD2  1 
ATOM   125   H HE1  . TYR A 1 59  ? -13.042 -6.436  17.754 1.00 20.43 ?  25   TYR A HE1  1 
ATOM   126   H HE2  . TYR A 1 59  ? -12.619 -10.059 16.111 1.00 24.71 ?  25   TYR A HE2  1 
ATOM   127   H HH   . TYR A 1 59  ? -14.062 -9.626  17.779 1.00 17.67 ?  25   TYR A HH   1 
ATOM   128   N N    . SER A 1 60  ? -9.765  -4.918  11.103 1.00 15.79 ?  26   SER A N    1 
ATOM   129   C CA   . SER A 1 60  ? -8.643  -4.632  10.214 1.00 17.84 ?  26   SER A CA   1 
ATOM   130   C C    . SER A 1 60  ? -7.799  -3.456  10.690 1.00 13.59 ?  26   SER A C    1 
ATOM   131   O O    . SER A 1 60  ? -6.568  -3.475  10.560 1.00 19.46 ?  26   SER A O    1 
ATOM   132   C CB   . SER A 1 60  ? -9.153  -4.359  8.797  1.00 20.65 ?  26   SER A CB   1 
ATOM   133   O OG   . SER A 1 60  ? -9.801  -5.493  8.260  1.00 25.26 ?  26   SER A OG   1 
ATOM   134   H H    . SER A 1 60  ? -10.530 -4.943  10.710 1.00 18.95 ?  26   SER A H    1 
ATOM   135   H HA   . SER A 1 60  ? -8.073  -5.417  10.203 1.00 21.40 ?  26   SER A HA   1 
ATOM   136   H HB2  . SER A 1 60  ? -9.782  -3.622  8.827  1.00 24.78 ?  26   SER A HB2  1 
ATOM   137   H HB3  . SER A 1 60  ? -8.400  -4.130  8.231  1.00 24.78 ?  26   SER A HB3  1 
ATOM   138   H HG   . SER A 1 60  ? -10.512 -5.644  8.681  1.00 30.31 ?  26   SER A HG   1 
ATOM   139   N N    . ASN A 1 61  ? -8.429  -2.419  11.217 1.00 13.59 ?  27   ASN A N    1 
ATOM   140   C CA   . ASN A 1 61  ? -7.720  -1.189  11.549 1.00 15.66 ?  27   ASN A CA   1 
ATOM   141   C C    . ASN A 1 61  ? -7.532  -1.013  13.041 1.00 13.00 ?  27   ASN A C    1 
ATOM   142   O O    . ASN A 1 61  ? -7.160  0.067   13.496 1.00 12.81 ?  27   ASN A O    1 
ATOM   143   C CB   . ASN A 1 61  ? -8.436  0.006   10.931 1.00 15.48 ?  27   ASN A CB   1 
ATOM   144   C CG   . ASN A 1 61  ? -8.634  -0.170  9.450  1.00 16.72 ?  27   ASN A CG   1 
ATOM   145   O OD1  . ASN A 1 61  ? -7.674  -0.417  8.717  1.00 19.30 ?  27   ASN A OD1  1 
ATOM   146   N ND2  . ASN A 1 61  ? -9.878  -0.096  9.008  1.00 17.34 ?  27   ASN A ND2  1 
ATOM   147   H H    . ASN A 1 61  ? -9.270  -2.401  11.394 1.00 16.31 ?  27   ASN A H    1 
ATOM   148   H HA   . ASN A 1 61  ? -6.832  -1.219  11.161 1.00 18.79 ?  27   ASN A HA   1 
ATOM   149   H HB2  . ASN A 1 61  ? -9.308  0.106   11.345 1.00 18.57 ?  27   ASN A HB2  1 
ATOM   150   H HB3  . ASN A 1 61  ? -7.907  0.806   11.075 1.00 18.57 ?  27   ASN A HB3  1 
ATOM   151   H HD21 . ASN A 1 61  ? -10.042 -0.190  8.169  1.00 20.81 ?  27   ASN A HD21 1 
ATOM   152   H HD22 . ASN A 1 61  ? -10.522 0.047   9.559  1.00 20.81 ?  27   ASN A HD22 1 
ATOM   153   N N    . TYR A 1 62  ? -7.750  -2.049  13.805 1.00 12.47 ?  28   TYR A N    1 
ATOM   154   C CA   . TYR A 1 62  ? -7.630  -1.954  15.244 1.00 9.74  ?  28   TYR A CA   1 
ATOM   155   C C    . TYR A 1 62  ? -6.171  -1.943  15.687 1.00 11.90 ?  28   TYR A C    1 
ATOM   156   O O    . TYR A 1 62  ? -5.278  -2.407  14.978 1.00 11.66 ?  28   TYR A O    1 
ATOM   157   C CB   . TYR A 1 62  ? -8.326  -3.143  15.895 1.00 10.61 ?  28   TYR A CB   1 
ATOM   158   C CG   . TYR A 1 62  ? -9.778  -2.961  16.257 1.00 10.70 ?  28   TYR A CG   1 
ATOM   159   C CD1  . TYR A 1 62  ? -10.689 -2.400  15.378 1.00 13.10 ?  28   TYR A CD1  1 
ATOM   160   C CD2  . TYR A 1 62  ? -10.243 -3.427  17.489 1.00 11.22 ?  28   TYR A CD2  1 
ATOM   161   C CE1  . TYR A 1 62  ? -12.044 -2.286  15.746 1.00 12.21 ?  28   TYR A CE1  1 
ATOM   162   C CE2  . TYR A 1 62  ? -11.561 -3.354  17.835 1.00 14.07 ?  28   TYR A CE2  1 
ATOM   163   C CZ   . TYR A 1 62  ? -12.441 -2.760  16.986 1.00 11.25 ?  28   TYR A CZ   1 
ATOM   164   O OH   . TYR A 1 62  ? -13.769 -2.706  17.354 1.00 14.95 ?  28   TYR A OH   1 
ATOM   165   H H    . TYR A 1 62  ? -7.971  -2.829  13.518 1.00 14.97 ?  28   TYR A H    1 
ATOM   166   H HA   . TYR A 1 62  ? -8.046  -1.128  15.537 1.00 11.69 ?  28   TYR A HA   1 
ATOM   167   H HB2  . TYR A 1 62  ? -8.278  -3.892  15.281 1.00 12.73 ?  28   TYR A HB2  1 
ATOM   168   H HB3  . TYR A 1 62  ? -7.854  -3.355  16.715 1.00 12.73 ?  28   TYR A HB3  1 
ATOM   169   H HD1  . TYR A 1 62  ? -10.407 -2.098  14.545 1.00 15.72 ?  28   TYR A HD1  1 
ATOM   170   H HD2  . TYR A 1 62  ? -9.638  -3.798  18.090 1.00 13.46 ?  28   TYR A HD2  1 
ATOM   171   H HE1  . TYR A 1 62  ? -12.661 -1.901  15.167 1.00 14.65 ?  28   TYR A HE1  1 
ATOM   172   H HE2  . TYR A 1 62  ? -11.855 -3.706  18.644 1.00 16.88 ?  28   TYR A HE2  1 
ATOM   173   H HH   . TYR A 1 62  ? -13.871 -3.047  18.114 1.00 17.94 ?  28   TYR A HH   1 
ATOM   174   N N    . PRO A 1 63  ? -5.917  -1.449  16.888 1.00 9.64  ?  29   PRO A N    1 
ATOM   175   C CA   . PRO A 1 63  ? -4.555  -1.462  17.428 1.00 9.66  ?  29   PRO A CA   1 
ATOM   176   C C    . PRO A 1 63  ? -4.078  -2.874  17.727 1.00 10.33 ?  29   PRO A C    1 
ATOM   177   O O    . PRO A 1 63  ? -4.852  -3.826  17.788 1.00 10.82 ?  29   PRO A O    1 
ATOM   178   C CB   . PRO A 1 63  ? -4.669  -0.648  18.725 1.00 10.06 ?  29   PRO A CB   1 
ATOM   179   C CG   . PRO A 1 63  ? -6.119  -0.288  18.869 1.00 14.53 ?  29   PRO A CG   1 
ATOM   180   C CD   . PRO A 1 63  ? -6.916  -1.018  17.872 1.00 10.40 ?  29   PRO A CD   1 
ATOM   181   H HA   . PRO A 1 63  ? -3.947  -1.029  16.809 1.00 11.59 ?  29   PRO A HA   1 
ATOM   182   H HB2  . PRO A 1 63  ? -4.374  -1.188  19.475 1.00 12.07 ?  29   PRO A HB2  1 
ATOM   183   H HB3  . PRO A 1 63  ? -4.123  0.151   18.656 1.00 12.07 ?  29   PRO A HB3  1 
ATOM   184   H HG2  . PRO A 1 63  ? -6.411  -0.527  19.763 1.00 17.44 ?  29   PRO A HG2  1 
ATOM   185   H HG3  . PRO A 1 63  ? -6.217  0.667   18.733 1.00 17.44 ?  29   PRO A HG3  1 
ATOM   186   H HD2  . PRO A 1 63  ? -7.355  -1.783  18.275 1.00 12.48 ?  29   PRO A HD2  1 
ATOM   187   H HD3  . PRO A 1 63  ? -7.574  -0.435  17.462 1.00 12.48 ?  29   PRO A HD3  1 
ATOM   188   N N    . GLU A 1 64  ? -2.782  -2.999  17.964 1.00 9.46  ?  30   GLU A N    1 
ATOM   189   C CA   . GLU A 1 64  ? -2.261  -4.240  18.506 1.00 9.01  ?  30   GLU A CA   1 
ATOM   190   C C    . GLU A 1 64  ? -2.838  -4.476  19.893 1.00 9.20  ?  30   GLU A C    1 
ATOM   191   O O    . GLU A 1 64  ? -3.174  -3.541  20.628 1.00 9.82  ?  30   GLU A O    1 
ATOM   192   C CB   . GLU A 1 64  ? -0.740  -4.181  18.594 1.00 10.70 ?  30   GLU A CB   1 
ATOM   193   C CG   . GLU A 1 64  ? -0.064  -3.907  17.264 1.00 12.03 ?  30   GLU A CG   1 
ATOM   194   C CD   . GLU A 1 64  ? -0.417  -4.910  16.190 1.00 22.33 ?  30   GLU A CD   1 
ATOM   195   O OE1  . GLU A 1 64  ? -0.305  -6.122  16.476 1.00 23.58 ?  30   GLU A OE1  1 
ATOM   196   O OE2  . GLU A 1 64  ? -0.787  -4.488  15.073 1.00 24.86 ?  30   GLU A OE2  1 
ATOM   197   H H    . GLU A 1 64  ? -2.192  -2.389  17.823 1.00 11.35 ?  30   GLU A H    1 
ATOM   198   H HA   . GLU A 1 64  ? -2.505  -4.979  17.926 1.00 10.81 ?  30   GLU A HA   1 
ATOM   199   H HB2  . GLU A 1 64  ? -0.491  -3.471  19.206 1.00 12.84 ?  30   GLU A HB2  1 
ATOM   200   H HB3  . GLU A 1 64  ? -0.413  -5.033  18.924 1.00 12.84 ?  30   GLU A HB3  1 
ATOM   201   H HG2  . GLU A 1 64  ? -0.334  -3.029  16.950 1.00 14.43 ?  30   GLU A HG2  1 
ATOM   202   H HG3  . GLU A 1 64  ? 0.898   -3.933  17.390 1.00 14.43 ?  30   GLU A HG3  1 
ATOM   203   N N    . PHE A 1 65  ? -2.922  -5.739  20.273 1.00 9.27  ?  31   PHE A N    1 
ATOM   204   C CA   . PHE A 1 65  ? -3.391  -6.129  21.592 1.00 8.80  ?  31   PHE A CA   1 
ATOM   205   C C    . PHE A 1 65  ? -2.735  -7.442  21.987 1.00 10.49 ?  31   PHE A C    1 
ATOM   206   O O    . PHE A 1 65  ? -2.631  -8.359  21.172 1.00 11.12 ?  31   PHE A O    1 
ATOM   207   C CB   . PHE A 1 65  ? -4.912  -6.299  21.661 1.00 8.87  ?  31   PHE A CB   1 
ATOM   208   C CG   . PHE A 1 65  ? -5.411  -6.678  23.016 1.00 8.55  ?  31   PHE A CG   1 
ATOM   209   C CD1  . PHE A 1 65  ? -5.717  -5.700  23.965 1.00 8.91  ?  31   PHE A CD1  1 
ATOM   210   C CD2  . PHE A 1 65  ? -5.532  -8.017  23.378 1.00 9.25  ?  31   PHE A CD2  1 
ATOM   211   C CE1  . PHE A 1 65  ? -6.160  -6.047  25.211 1.00 11.29 ?  31   PHE A CE1  1 
ATOM   212   C CE2  . PHE A 1 65  ? -5.959  -8.368  24.624 1.00 10.44 ?  31   PHE A CE2  1 
ATOM   213   C CZ   . PHE A 1 65  ? -6.278  -7.380  25.561 1.00 10.01 ?  31   PHE A CZ   1 
ATOM   214   H H    . PHE A 1 65  ? -2.709  -6.407  19.774 1.00 11.12 ?  31   PHE A H    1 
ATOM   215   H HA   . PHE A 1 65  ? -3.134  -5.433  22.217 1.00 10.56 ?  31   PHE A HA   1 
ATOM   216   H HB2  . PHE A 1 65  ? -5.332  -5.460  21.414 1.00 10.64 ?  31   PHE A HB2  1 
ATOM   217   H HB3  . PHE A 1 65  ? -5.177  -6.997  21.041 1.00 10.64 ?  31   PHE A HB3  1 
ATOM   218   H HD1  . PHE A 1 65  ? -5.619  -4.801  23.746 1.00 10.69 ?  31   PHE A HD1  1 
ATOM   219   H HD2  . PHE A 1 65  ? -5.319  -8.680  22.762 1.00 11.09 ?  31   PHE A HD2  1 
ATOM   220   H HE1  . PHE A 1 65  ? -6.382  -5.385  25.825 1.00 13.55 ?  31   PHE A HE1  1 
ATOM   221   H HE2  . PHE A 1 65  ? -6.038  -9.266  24.851 1.00 12.53 ?  31   PHE A HE2  1 
ATOM   222   H HZ   . PHE A 1 65  ? -6.567  -7.617  26.413 1.00 12.01 ?  31   PHE A HZ   1 
ATOM   223   N N    . SER A 1 66  ? -2.319  -7.527  23.244 1.00 9.08  ?  32   SER A N    1 
ATOM   224   C CA   . SER A 1 66  ? -1.877  -8.775  23.833 1.00 9.85  ?  32   SER A CA   1 
ATOM   225   C C    . SER A 1 66  ? -2.319  -8.845  25.284 1.00 11.93 ?  32   SER A C    1 
ATOM   226   O O    . SER A 1 66  ? -2.329  -7.844  26.001 1.00 11.84 ?  32   SER A O    1 
ATOM   227   C CB   . SER A 1 66  ? -0.360  -8.837  23.782 1.00 12.22 ?  32   SER A CB   1 
ATOM   228   O OG   . SER A 1 66  ? 0.129   -10.007 24.426 1.00 13.95 ?  32   SER A OG   1 
ATOM   229   H H    . SER A 1 66  ? -2.285  -6.859  23.785 1.00 10.89 ?  32   SER A H    1 
ATOM   230   H HA   . SER A 1 66  ? -2.270  -9.528  23.366 1.00 11.82 ?  32   SER A HA   1 
ATOM   231   H HB2  . SER A 1 66  ? -0.076  -8.847  22.854 1.00 14.66 ?  32   SER A HB2  1 
ATOM   232   H HB3  . SER A 1 66  ? 0.002   -8.057  24.231 1.00 14.66 ?  32   SER A HB3  1 
ATOM   233   H HG   . SER A 1 66  ? 0.893   -9.863  24.742 1.00 16.74 ?  32   SER A HG   1 
ATOM   234   N N    . TRP A 1 67  ? -2.649  -10.052 25.729 1.00 12.03 ?  33   TRP A N    1 
ATOM   235   C CA   . TRP A 1 67  ? -2.899  -10.297 27.138 1.00 11.21 ?  33   TRP A CA   1 
ATOM   236   C C    . TRP A 1 67  ? -1.620  -10.578 27.923 1.00 10.92 ?  33   TRP A C    1 
ATOM   237   O O    . TRP A 1 67  ? -1.695  -10.818 29.131 1.00 12.01 ?  33   TRP A O    1 
ATOM   238   C CB   . TRP A 1 67  ? -3.823  -11.502 27.294 1.00 12.67 ?  33   TRP A CB   1 
ATOM   239   C CG   . TRP A 1 67  ? -5.247  -11.310 26.892 1.00 11.05 ?  33   TRP A CG   1 
ATOM   240   C CD1  . TRP A 1 67  ? -5.894  -11.900 25.832 1.00 11.44 ?  33   TRP A CD1  1 
ATOM   241   C CD2  . TRP A 1 67  ? -6.240  -10.551 27.586 1.00 10.54 ?  33   TRP A CD2  1 
ATOM   242   N NE1  . TRP A 1 67  ? -7.211  -11.520 25.810 1.00 11.16 ?  33   TRP A NE1  1 
ATOM   243   C CE2  . TRP A 1 67  ? -7.454  -10.691 26.875 1.00 10.54 ?  33   TRP A CE2  1 
ATOM   244   C CE3  . TRP A 1 67  ? -6.220  -9.733  28.723 1.00 11.08 ?  33   TRP A CE3  1 
ATOM   245   C CZ2  . TRP A 1 67  ? -8.623  -10.062 27.275 1.00 10.59 ?  33   TRP A CZ2  1 
ATOM   246   C CZ3  . TRP A 1 67  ? -7.391  -9.100  29.105 1.00 12.34 ?  33   TRP A CZ3  1 
ATOM   247   C CH2  . TRP A 1 67  ? -8.567  -9.266  28.384 1.00 11.14 ?  33   TRP A CH2  1 
ATOM   248   H H    . TRP A 1 67  ? -2.733  -10.748 25.230 1.00 14.43 ?  33   TRP A H    1 
ATOM   249   H HA   . TRP A 1 67  ? -3.332  -9.514  27.512 1.00 13.45 ?  33   TRP A HA   1 
ATOM   250   H HB2  . TRP A 1 67  ? -3.470  -12.224 26.751 1.00 15.21 ?  33   TRP A HB2  1 
ATOM   251   H HB3  . TRP A 1 67  ? -3.825  -11.760 28.229 1.00 15.21 ?  33   TRP A HB3  1 
ATOM   252   H HD1  . TRP A 1 67  ? -5.496  -12.475 25.218 1.00 13.73 ?  33   TRP A HD1  1 
ATOM   253   H HE1  . TRP A 1 67  ? -7.791  -11.762 25.223 1.00 13.39 ?  33   TRP A HE1  1 
ATOM   254   H HE3  . TRP A 1 67  ? -5.436  -9.618  29.211 1.00 13.30 ?  33   TRP A HE3  1 
ATOM   255   H HZ2  . TRP A 1 67  ? -9.417  -10.177 26.804 1.00 12.70 ?  33   TRP A HZ2  1 
ATOM   256   H HZ3  . TRP A 1 67  ? -7.391  -8.554  29.858 1.00 14.80 ?  33   TRP A HZ3  1 
ATOM   257   H HH2  . TRP A 1 67  ? -9.336  -8.825  28.664 1.00 13.37 ?  33   TRP A HH2  1 
ATOM   258   N N    . ASP A 1 68  ? -0.454  -10.539 27.287 1.00 11.43 ?  34   ASP A N    1 
ATOM   259   C CA   . ASP A 1 68  ? 0.747   -11.023 27.976 1.00 13.32 ?  34   ASP A CA   1 
ATOM   260   C C    . ASP A 1 68  ? 1.026   -10.222 29.245 1.00 13.18 ?  34   ASP A C    1 
ATOM   261   O O    . ASP A 1 68  ? 1.423   -10.788 30.274 1.00 12.18 ?  34   ASP A O    1 
ATOM   262   C CB   . ASP A 1 68  ? 1.967   -10.971 27.071 1.00 13.72 ?  34   ASP A CB   1 
ATOM   263   C CG   . ASP A 1 68  ? 1.969   -12.036 25.991 1.00 16.66 ?  34   ASP A CG   1 
ATOM   264   O OD1  . ASP A 1 68  ? 1.095   -12.921 26.007 1.00 18.06 ?  34   ASP A OD1  1 
ATOM   265   O OD2  . ASP A 1 68  ? 2.861   -11.944 25.125 1.00 20.04 ?  34   ASP A OD2  1 
ATOM   266   H H    . ASP A 1 68  ? -0.330  -10.249 26.486 1.00 13.71 ?  34   ASP A H    1 
ATOM   267   H HA   . ASP A 1 68  ? 0.587   -11.950 28.212 1.00 15.99 ?  34   ASP A HA   1 
ATOM   268   H HB2  . ASP A 1 68  ? 1.996   -10.106 26.634 1.00 16.47 ?  34   ASP A HB2  1 
ATOM   269   H HB3  . ASP A 1 68  ? 2.763   -11.096 27.612 1.00 16.47 ?  34   ASP A HB3  1 
ATOM   270   N N    . THR A 1 69  ? 0.890   -8.895  29.168 1.00 11.71 ?  35   THR A N    1 
ATOM   271   C CA   . THR A 1 69  ? 1.029   -7.976  30.296 1.00 11.30 ?  35   THR A CA   1 
ATOM   272   C C    . THR A 1 69  ? -0.093  -6.952  30.167 1.00 9.98  ?  35   THR A C    1 
ATOM   273   O O    . THR A 1 69  ? -0.824  -6.948  29.183 1.00 10.51 ?  35   THR A O    1 
ATOM   274   C CB   . THR A 1 69  ? 2.399   -7.285  30.312 1.00 11.68 ?  35   THR A CB   1 
ATOM   275   O OG1  . THR A 1 69  ? 2.573   -6.543  29.107 1.00 13.43 ?  35   THR A OG1  1 
ATOM   276   C CG2  . THR A 1 69  ? 3.528   -8.300  30.448 1.00 13.93 ?  35   THR A CG2  1 
ATOM   277   H H    . THR A 1 69  ? 0.707   -8.484  28.435 1.00 14.05 ?  35   THR A H    1 
ATOM   278   H HA   . THR A 1 69  ? 0.943   -8.467  31.128 1.00 13.56 ?  35   THR A HA   1 
ATOM   279   H HB   . THR A 1 69  ? 2.443   -6.687  31.074 1.00 14.01 ?  35   THR A HB   1 
ATOM   280   H HG1  . THR A 1 69  ? 2.065   -5.874  29.106 1.00 16.11 ?  35   THR A HG1  1 
ATOM   281   H HG21 . THR A 1 69  ? 4.378   -7.841  30.536 1.00 16.72 ?  35   THR A HG21 1 
ATOM   282   H HG22 . THR A 1 69  ? 3.385   -8.852  31.234 1.00 16.72 ?  35   THR A HG22 1 
ATOM   283   H HG23 . THR A 1 69  ? 3.558   -8.871  29.664 1.00 16.72 ?  35   THR A HG23 1 
ATOM   284   N N    . MET A 1 70  ? -0.221  -6.063  31.145 1.00 10.09 ?  36   MET A N    1 
ATOM   285   C CA   . MET A 1 70  ? -1.333  -5.115  31.173 1.00 10.28 ?  36   MET A CA   1 
ATOM   286   C C    . MET A 1 70  ? -1.460  -4.366  29.846 1.00 10.13 ?  36   MET A C    1 
ATOM   287   O O    . MET A 1 70  ? -0.478  -3.769  29.373 1.00 10.11 ?  36   MET A O    1 
ATOM   288   C CB   . MET A 1 70  ? -1.098  -4.050  32.239 1.00 9.69  ?  36   MET A CB   1 
ATOM   289   C CG   . MET A 1 70  ? -2.314  -3.398  32.941 1.00 13.53 ?  36   MET A CG   1 
ATOM   290   S SD   . MET A 1 70  ? -3.687  -4.417  33.404 1.00 12.18 ?  36   MET A SD   1 
ATOM   291   C CE   . MET A 1 70  ? -2.910  -5.198  34.823 1.00 15.66 ?  36   MET A CE   1 
ATOM   292   H H    . MET A 1 70  ? 0.322   -5.985  31.808 1.00 12.10 ?  36   MET A H    1 
ATOM   293   H HA   . MET A 1 70  ? -2.134  -5.627  31.362 1.00 12.33 ?  36   MET A HA   1 
ATOM   294   H HB2  . MET A 1 70  ? -0.565  -4.455  32.941 1.00 11.63 ?  36   MET A HB2  1 
ATOM   295   H HB3  . MET A 1 70  ? -0.604  -3.327  31.822 1.00 11.63 ?  36   MET A HB3  1 
ATOM   296   H HG2  . MET A 1 70  ? -1.993  -2.985  33.757 1.00 16.24 ?  36   MET A HG2  1 
ATOM   297   H HG3  . MET A 1 70  ? -2.667  -2.720  32.343 1.00 16.24 ?  36   MET A HG3  1 
ATOM   298   H HE1  . MET A 1 70  ? -3.537  -5.819  35.225 1.00 18.79 ?  36   MET A HE1  1 
ATOM   299   H HE2  . MET A 1 70  ? -2.117  -5.673  34.527 1.00 18.79 ?  36   MET A HE2  1 
ATOM   300   H HE3  . MET A 1 70  ? -2.664  -4.514  35.465 1.00 18.79 ?  36   MET A HE3  1 
ATOM   301   N N    . PRO A 1 71  ? -2.649  -4.345  29.236 1.00 9.37  ?  37   PRO A N    1 
ATOM   302   C CA   . PRO A 1 71  ? -2.848  -3.534  28.019 1.00 9.16  ?  37   PRO A CA   1 
ATOM   303   C C    . PRO A 1 71  ? -3.049  -2.069  28.400 1.00 7.93  ?  37   PRO A C    1 
ATOM   304   O O    . PRO A 1 71  ? -3.957  -1.739  29.163 1.00 9.20  ?  37   PRO A O    1 
ATOM   305   C CB   . PRO A 1 71  ? -4.107  -4.140  27.389 1.00 9.82  ?  37   PRO A CB   1 
ATOM   306   C CG   . PRO A 1 71  ? -4.845  -4.733  28.541 1.00 11.27 ?  37   PRO A CG   1 
ATOM   307   C CD   . PRO A 1 71  ? -3.806  -5.219  29.513 1.00 8.78  ?  37   PRO A CD   1 
ATOM   308   H HA   . PRO A 1 71  ? -2.103  -3.620  27.405 1.00 11.00 ?  37   PRO A HA   1 
ATOM   309   H HB2  . PRO A 1 71  ? -4.631  -3.447  26.958 1.00 11.78 ?  37   PRO A HB2  1 
ATOM   310   H HB3  . PRO A 1 71  ? -3.862  -4.821  26.743 1.00 11.78 ?  37   PRO A HB3  1 
ATOM   311   H HG2  . PRO A 1 71  ? -5.404  -4.055  28.951 1.00 13.52 ?  37   PRO A HG2  1 
ATOM   312   H HG3  . PRO A 1 71  ? -5.392  -5.471  28.230 1.00 13.52 ?  37   PRO A HG3  1 
ATOM   313   H HD2  . PRO A 1 71  ? -4.111  -5.109  30.427 1.00 10.54 ?  37   PRO A HD2  1 
ATOM   314   H HD3  . PRO A 1 71  ? -3.585  -6.148  29.346 1.00 10.54 ?  37   PRO A HD3  1 
ATOM   315   N N    . LEU A 1 72  ? -2.187  -1.203  27.868 1.00 9.37  ?  38   LEU A N    1 
ATOM   316   C CA   . LEU A 1 72  ? -2.089  0.190   28.298 1.00 8.36  ?  38   LEU A CA   1 
ATOM   317   C C    . LEU A 1 72  ? -2.499  1.189   27.221 1.00 9.38  ?  38   LEU A C    1 
ATOM   318   O O    . LEU A 1 72  ? -2.211  1.007   26.035 1.00 9.87  ?  38   LEU A O    1 
ATOM   319   C CB   . LEU A 1 72  ? -0.656  0.515   28.724 1.00 10.32 ?  38   LEU A CB   1 
ATOM   320   C CG   . LEU A 1 72  ? -0.095  -0.347  29.849 1.00 10.04 ?  38   LEU A CG   1 
ATOM   321   C CD1  . LEU A 1 72  ? 1.347   0.082   30.115 1.00 11.59 ?  38   LEU A CD1  1 
ATOM   322   C CD2  . LEU A 1 72  ? -0.923  -0.263  31.111 1.00 10.83 ?  38   LEU A CD2  1 
ATOM   323   H H    . LEU A 1 72  ? -1.635  -1.404  27.240 1.00 11.25 ?  38   LEU A H    1 
ATOM   324   H HA   . LEU A 1 72  ? -2.709  0.301   29.035 1.00 10.03 ?  38   LEU A HA   1 
ATOM   325   H HB2  . LEU A 1 72  ? -0.077  0.401   27.955 1.00 12.38 ?  38   LEU A HB2  1 
ATOM   326   H HB3  . LEU A 1 72  ? -0.630  1.437   29.025 1.00 12.38 ?  38   LEU A HB3  1 
ATOM   327   H HG   . LEU A 1 72  ? -0.119  -1.278  29.578 1.00 12.05 ?  38   LEU A HG   1 
ATOM   328   H HD11 . LEU A 1 72  ? 1.725   -0.492  30.800 1.00 13.91 ?  38   LEU A HD11 1 
ATOM   329   H HD12 . LEU A 1 72  ? 1.858   -0.001  29.295 1.00 13.91 ?  38   LEU A HD12 1 
ATOM   330   H HD13 . LEU A 1 72  ? 1.351   1.004   30.416 1.00 13.91 ?  38   LEU A HD13 1 
ATOM   331   H HD21 . LEU A 1 72  ? -0.550  -0.865  31.774 1.00 12.99 ?  38   LEU A HD21 1 
ATOM   332   H HD22 . LEU A 1 72  ? -0.901  0.648   31.443 1.00 12.99 ?  38   LEU A HD22 1 
ATOM   333   H HD23 . LEU A 1 72  ? -1.836  -0.519  30.908 1.00 12.99 ?  38   LEU A HD23 1 
ATOM   334   N N    . TYR A 1 73  ? -3.127  2.287   27.678 1.00 8.08  ?  39   TYR A N    1 
ATOM   335   C CA   . TYR A 1 73  ? -3.559  3.414   26.863 1.00 8.78  ?  39   TYR A CA   1 
ATOM   336   C C    . TYR A 1 73  ? -2.800  4.660   27.282 1.00 7.72  ?  39   TYR A C    1 
ATOM   337   O O    . TYR A 1 73  ? -2.498  4.852   28.459 1.00 8.69  ?  39   TYR A O    1 
ATOM   338   C CB   . TYR A 1 73  ? -5.056  3.642   27.118 1.00 8.50  ?  39   TYR A CB   1 
ATOM   339   C CG   . TYR A 1 73  ? -5.698  4.870   26.504 1.00 6.82  ?  39   TYR A CG   1 
ATOM   340   C CD1  . TYR A 1 73  ? -5.737  5.030   25.136 1.00 7.63  ?  39   TYR A CD1  1 
ATOM   341   C CD2  . TYR A 1 73  ? -6.331  5.828   27.294 1.00 6.69  ?  39   TYR A CD2  1 
ATOM   342   C CE1  . TYR A 1 73  ? -6.359  6.129   24.569 1.00 7.92  ?  39   TYR A CE1  1 
ATOM   343   C CE2  . TYR A 1 73  ? -6.982  6.918   26.728 1.00 6.70  ?  39   TYR A CE2  1 
ATOM   344   C CZ   . TYR A 1 73  ? -6.978  7.055   25.373 1.00 6.41  ?  39   TYR A CZ   1 
ATOM   345   O OH   . TYR A 1 73  ? -7.585  8.135   24.759 1.00 7.97  ?  39   TYR A OH   1 
ATOM   346   H H    . TYR A 1 73  ? -3.321  2.399   28.508 1.00 9.70  ?  39   TYR A H    1 
ATOM   347   H HA   . TYR A 1 73  ? -3.389  3.256   25.921 1.00 10.54 ?  39   TYR A HA   1 
ATOM   348   H HB2  . TYR A 1 73  ? -5.536  2.874   26.770 1.00 10.20 ?  39   TYR A HB2  1 
ATOM   349   H HB3  . TYR A 1 73  ? -5.187  3.709   28.076 1.00 10.20 ?  39   TYR A HB3  1 
ATOM   350   H HD1  . TYR A 1 73  ? -5.342  4.392   24.588 1.00 9.16  ?  39   TYR A HD1  1 
ATOM   351   H HD2  . TYR A 1 73  ? -6.318  5.736   28.220 1.00 8.03  ?  39   TYR A HD2  1 
ATOM   352   H HE1  . TYR A 1 73  ? -6.357  6.241   23.646 1.00 9.50  ?  39   TYR A HE1  1 
ATOM   353   H HE2  . TYR A 1 73  ? -7.413  7.543   27.266 1.00 8.05  ?  39   TYR A HE2  1 
ATOM   354   H HH   . TYR A 1 73  ? -8.309  8.315   25.145 1.00 9.57  ?  39   TYR A HH   1 
ATOM   355   N N    . MET A 1 74  ? -2.527  5.534   26.321 1.00 7.67  ?  40   MET A N    1 
ATOM   356   C CA   . MET A 1 74  ? -1.939  6.833   26.627 1.00 6.95  ?  40   MET A CA   1 
ATOM   357   C C    . MET A 1 74  ? -2.796  7.933   26.034 1.00 7.54  ?  40   MET A C    1 
ATOM   358   O O    . MET A 1 74  ? -3.342  7.791   24.944 1.00 8.20  ?  40   MET A O    1 
ATOM   359   C CB   . MET A 1 74  ? -0.487  6.908   26.151 1.00 7.79  ?  40   MET A CB   1 
ATOM   360   C CG   . MET A 1 74  ? 0.288   8.204   26.449 1.00 10.15 ?  40   MET A CG   1 
ATOM   361   S SD   . MET A 1 74  ? 0.177   8.839   28.133 1.00 9.55  ?  40   MET A SD   1 
ATOM   362   C CE   . MET A 1 74  ? 0.905   7.490   29.064 1.00 10.96 ?  40   MET A CE   1 
ATOM   363   H H    . MET A 1 74  ? -2.673  5.398   25.484 1.00 9.20  ?  40   MET A H    1 
ATOM   364   H HA   . MET A 1 74  ? -1.920  6.972   27.587 1.00 8.34  ?  40   MET A HA   1 
ATOM   365   H HB2  . MET A 1 74  ? 0.003   6.185   26.573 1.00 9.34  ?  40   MET A HB2  1 
ATOM   366   H HB3  . MET A 1 74  ? -0.483  6.794   25.188 1.00 9.34  ?  40   MET A HB3  1 
ATOM   367   H HG2  . MET A 1 74  ? 1.227   8.042   26.268 1.00 12.18 ?  40   MET A HG2  1 
ATOM   368   H HG3  . MET A 1 74  ? -0.048  8.898   25.861 1.00 12.18 ?  40   MET A HG3  1 
ATOM   369   H HE1  . MET A 1 74  ? 0.891   7.714   30.008 1.00 13.15 ?  40   MET A HE1  1 
ATOM   370   H HE2  . MET A 1 74  ? 0.389   6.684   28.907 1.00 13.15 ?  40   MET A HE2  1 
ATOM   371   H HE3  . MET A 1 74  ? 1.820   7.360   28.768 1.00 13.15 ?  40   MET A HE3  1 
ATOM   372   N N    . HIS A 1 75  ? -2.887  9.041   26.765 1.00 7.48  ?  41   HIS A N    1 
ATOM   373   C CA   . HIS A 1 75  ? -3.791  10.150  26.450 1.00 7.87  ?  41   HIS A CA   1 
ATOM   374   C C    . HIS A 1 75  ? -3.051  11.380  26.959 1.00 6.75  ?  41   HIS A C    1 
ATOM   375   O O    . HIS A 1 75  ? -2.862  11.511  28.170 1.00 7.94  ?  41   HIS A O    1 
ATOM   376   C CB   . HIS A 1 75  ? -5.119  9.917   27.169 1.00 7.31  ?  41   HIS A CB   1 
ATOM   377   C CG   . HIS A 1 75  ? -6.207  10.854  26.757 1.00 6.79  ?  41   HIS A CG   1 
ATOM   378   N ND1  . HIS A 1 75  ? -7.306  10.472  26.008 1.00 6.75  ?  41   HIS A ND1  1 
ATOM   379   C CD2  . HIS A 1 75  ? -6.353  12.177  27.002 1.00 6.77  ?  41   HIS A CD2  1 
ATOM   380   C CE1  . HIS A 1 75  ? -8.073  11.534  25.807 1.00 6.04  ?  41   HIS A CE1  1 
ATOM   381   N NE2  . HIS A 1 75  ? -7.525  12.573  26.414 1.00 7.18  ?  41   HIS A NE2  1 
ATOM   382   H H    . HIS A 1 75  ? -2.421  9.182   27.473 1.00 8.98  ?  41   HIS A H    1 
ATOM   383   H HA   . HIS A 1 75  ? -3.980  10.255  25.504 1.00 9.44  ?  41   HIS A HA   1 
ATOM   384   H HB2  . HIS A 1 75  ? -5.421  9.014   26.980 1.00 8.77  ?  41   HIS A HB2  1 
ATOM   385   H HB3  . HIS A 1 75  ? -4.980  10.027  28.123 1.00 8.77  ?  41   HIS A HB3  1 
ATOM   386   H HD2  . HIS A 1 75  ? -5.767  12.717  27.482 1.00 8.13  ?  41   HIS A HD2  1 
ATOM   387   H HE1  . HIS A 1 75  ? -8.865  11.545  25.319 1.00 7.24  ?  41   HIS A HE1  1 
ATOM   388   H HE2  . HIS A 1 75  ? -7.852  13.369  26.435 1.00 8.61  ?  41   HIS A HE2  1 
ATOM   389   N N    . VAL A 1 76  ? -2.563  12.245  26.069 1.00 6.85  ?  42   VAL A N    1 
ATOM   390   C CA   . VAL A 1 76  ? -1.489  13.146  26.484 1.00 7.53  ?  42   VAL A CA   1 
ATOM   391   C C    . VAL A 1 76  ? -1.450  14.445  25.695 1.00 6.13  ?  42   VAL A C    1 
ATOM   392   O O    . VAL A 1 76  ? -1.769  14.501  24.502 1.00 6.51  ?  42   VAL A O    1 
ATOM   393   C CB   . VAL A 1 76  ? -0.133  12.401  26.379 1.00 7.99  ?  42   VAL A CB   1 
ATOM   394   C CG1  . VAL A 1 76  ? 0.191   12.056  24.910 1.00 8.94  ?  42   VAL A CG1  1 
ATOM   395   C CG2  . VAL A 1 76  ? 1.007   13.158  27.044 1.00 9.61  ?  42   VAL A CG2  1 
ATOM   396   H H    . VAL A 1 76  ? -2.826  12.325  25.254 1.00 8.22  ?  42   VAL A H    1 
ATOM   397   H HA   . VAL A 1 76  ? -1.682  13.428  27.391 1.00 9.04  ?  42   VAL A HA   1 
ATOM   398   H HB   . VAL A 1 76  ? -0.219  11.569  26.870 1.00 9.59  ?  42   VAL A HB   1 
ATOM   399   H HG11 . VAL A 1 76  ? 0.954   11.458  24.887 1.00 10.73 ?  42   VAL A HG11 1 
ATOM   400   H HG12 . VAL A 1 76  ? -0.580  11.623  24.510 1.00 10.73 ?  42   VAL A HG12 1 
ATOM   401   H HG13 . VAL A 1 76  ? 0.396   12.874  24.431 1.00 10.73 ?  42   VAL A HG13 1 
ATOM   402   H HG21 . VAL A 1 76  ? 1.739   12.544  27.210 1.00 11.54 ?  42   VAL A HG21 1 
ATOM   403   H HG22 . VAL A 1 76  ? 1.300   13.870  26.454 1.00 11.54 ?  42   VAL A HG22 1 
ATOM   404   H HG23 . VAL A 1 76  ? 0.692   13.531  27.882 1.00 11.54 ?  42   VAL A HG23 1 
ATOM   405   N N    . ARG A 1 77  ? -1.001  15.500  26.380 1.00 6.55  ?  43   ARG A N    1 
ATOM   406   C CA   . ARG A 1 77  ? -0.553  16.733  25.744 1.00 7.22  ?  43   ARG A CA   1 
ATOM   407   C C    . ARG A 1 77  ? 0.695   17.230  26.470 1.00 7.05  ?  43   ARG A C    1 
ATOM   408   O O    . ARG A 1 77  ? 1.016   16.793  27.581 1.00 7.94  ?  43   ARG A O    1 
ATOM   409   C CB   . ARG A 1 77  ? -1.628  17.829  25.713 1.00 7.73  ?  43   ARG A CB   1 
ATOM   410   C CG   . ARG A 1 77  ? -2.069  18.312  27.069 1.00 7.21  ?  43   ARG A CG   1 
ATOM   411   C CD   . ARG A 1 77  ? -3.194  19.335  26.981 1.00 7.55  ?  43   ARG A CD   1 
ATOM   412   N NE   . ARG A 1 77  ? -3.679  19.734  28.301 1.00 7.62  ?  43   ARG A NE   1 
ATOM   413   C CZ   . ARG A 1 77  ? -3.206  20.732  29.027 1.00 8.39  ?  43   ARG A CZ   1 
ATOM   414   N NH1  . ARG A 1 77  ? -2.195  21.467  28.611 1.00 8.99  ?  43   ARG A NH1  1 
ATOM   415   N NH2  . ARG A 1 77  ? -3.778  20.999  30.198 1.00 10.52 ?  43   ARG A NH2  1 
ATOM   416   H H    . ARG A 1 77  ? -0.946  15.523  27.238 1.00 7.85  ?  43   ARG A H    1 
ATOM   417   H HA   . ARG A 1 77  ? -0.327  16.541  24.821 1.00 8.66  ?  43   ARG A HA   1 
ATOM   418   H HB2  . ARG A 1 77  ? -1.275  18.593  25.231 1.00 9.27  ?  43   ARG A HB2  1 
ATOM   419   H HB3  . ARG A 1 77  ? -2.410  17.481  25.258 1.00 9.27  ?  43   ARG A HB3  1 
ATOM   420   H HG2  . ARG A 1 77  ? -2.388  17.557  27.587 1.00 8.65  ?  43   ARG A HG2  1 
ATOM   421   H HG3  . ARG A 1 77  ? -1.317  18.729  27.518 1.00 8.65  ?  43   ARG A HG3  1 
ATOM   422   H HD2  . ARG A 1 77  ? -2.870  20.127  26.526 1.00 9.06  ?  43   ARG A HD2  1 
ATOM   423   H HD3  . ARG A 1 77  ? -3.937  18.950  26.490 1.00 9.06  ?  43   ARG A HD3  1 
ATOM   424   H HE   . ARG A 1 77  ? -4.329  19.280  28.634 1.00 9.15  ?  43   ARG A HE   1 
ATOM   425   H HH11 . ARG A 1 77  ? -1.828  21.303  27.851 1.00 10.79 ?  43   ARG A HH11 1 
ATOM   426   H HH12 . ARG A 1 77  ? -1.902  22.112  29.099 1.00 10.79 ?  43   ARG A HH12 1 
ATOM   427   H HH21 . ARG A 1 77  ? -4.443  20.525  30.469 1.00 12.62 ?  43   ARG A HH21 1 
ATOM   428   H HH22 . ARG A 1 77  ? -3.483  21.644  30.684 1.00 12.62 ?  43   ARG A HH22 1 
ATOM   429   N N    . LYS A 1 78  ? 1.388   18.154  25.813 1.00 6.45  ?  44   LYS A N    1 
ATOM   430   C CA   . LYS A 1 78  ? 2.566   18.848  26.325 1.00 7.63  ?  44   LYS A CA   1 
ATOM   431   C C    . LYS A 1 78  ? 2.619   20.168  25.559 1.00 6.80  ?  44   LYS A C    1 
ATOM   432   O O    . LYS A 1 78  ? 2.276   20.205  24.377 1.00 6.89  ?  44   LYS A O    1 
ATOM   433   C CB   . LYS A 1 78  ? 3.842   18.040  26.052 1.00 7.88  ?  44   LYS A CB   1 
ATOM   434   C CG   . LYS A 1 78  ? 5.053   18.533  26.823 1.00 8.26  ?  44   LYS A CG   1 
ATOM   435   C CD   . LYS A 1 78  ? 6.326   17.779  26.441 1.00 9.73  ?  44   LYS A CD   1 
ATOM   436   C CE   . LYS A 1 78  ? 7.550   18.417  27.061 1.00 8.31  ?  44   LYS A CE   1 
ATOM   437   N NZ   . LYS A 1 78  ? 8.820   17.798  26.548 1.00 8.98  ?  44   LYS A NZ   1 
ATOM   438   H H    . LYS A 1 78  ? 1.184   18.414  25.019 1.00 7.73  ?  44   LYS A H    1 
ATOM   439   H HA   . LYS A 1 78  ? 2.509   18.999  27.281 1.00 9.16  ?  44   LYS A HA   1 
ATOM   440   H HB2  . LYS A 1 78  ? 3.686   17.116  26.303 1.00 9.46  ?  44   LYS A HB2  1 
ATOM   441   H HB3  . LYS A 1 78  ? 4.050   18.096  25.106 1.00 9.46  ?  44   LYS A HB3  1 
ATOM   442   H HG2  . LYS A 1 78  ? 5.190   19.474  26.633 1.00 9.91  ?  44   LYS A HG2  1 
ATOM   443   H HG3  . LYS A 1 78  ? 4.900   18.405  27.773 1.00 9.91  ?  44   LYS A HG3  1 
ATOM   444   H HD2  . LYS A 1 78  ? 6.265   16.864  26.756 1.00 11.67 ?  44   LYS A HD2  1 
ATOM   445   H HD3  . LYS A 1 78  ? 6.430   17.792  25.476 1.00 11.67 ?  44   LYS A HD3  1 
ATOM   446   H HE2  . LYS A 1 78  ? 7.563   19.362  26.844 1.00 9.97  ?  44   LYS A HE2  1 
ATOM   447   H HE3  . LYS A 1 78  ? 7.520   18.298  28.023 1.00 9.97  ?  44   LYS A HE3  1 
ATOM   448   H HZ1  . LYS A 1 78  ? 8.807   16.919  26.687 1.00 10.77 ?  44   LYS A HZ1  1 
ATOM   449   H HZ2  . LYS A 1 78  ? 8.903   17.952  25.676 1.00 10.77 ?  44   LYS A HZ2  1 
ATOM   450   H HZ3  . LYS A 1 78  ? 9.521   18.147  26.971 1.00 10.77 ?  44   LYS A HZ3  1 
ATOM   451   N N    . ASN A 1 79  ? 3.025   21.260  26.210 1.00 7.64  ?  45   ASN A N    1 
ATOM   452   C CA   . ASN A 1 79  ? 2.965   22.549  25.527 1.00 7.51  ?  45   ASN A CA   1 
ATOM   453   C C    . ASN A 1 79  ? 4.118   22.754  24.548 1.00 8.73  ?  45   ASN A C    1 
ATOM   454   O O    . ASN A 1 79  ? 4.023   23.612  23.656 1.00 9.12  ?  45   ASN A O    1 
ATOM   455   C CB   . ASN A 1 79  ? 2.963   23.698  26.535 1.00 8.29  ?  45   ASN A CB   1 
ATOM   456   C CG   . ASN A 1 79  ? 1.692   23.767  27.337 1.00 8.36  ?  45   ASN A CG   1 
ATOM   457   O OD1  . ASN A 1 79  ? 0.639   24.093  26.804 1.00 9.93  ?  45   ASN A OD1  1 
ATOM   458   N ND2  . ASN A 1 79  ? 1.776   23.429  28.620 1.00 9.52  ?  45   ASN A ND2  1 
ATOM   459   H H    . ASN A 1 79  ? 3.326   21.278  27.015 1.00 9.16  ?  45   ASN A H    1 
ATOM   460   H HA   . ASN A 1 79  ? 2.131   22.584  25.033 1.00 9.01  ?  45   ASN A HA   1 
ATOM   461   H HB2  . ASN A 1 79  ? 3.701   23.578  27.152 1.00 9.95  ?  45   ASN A HB2  1 
ATOM   462   H HB3  . ASN A 1 79  ? 3.062   24.537  26.058 1.00 9.95  ?  45   ASN A HB3  1 
ATOM   463   H HD21 . ASN A 1 79  ? 1.075   23.453  29.117 1.00 11.43 ?  45   ASN A HD21 1 
ATOM   464   H HD22 . ASN A 1 79  ? 2.531   23.185  28.952 1.00 11.43 ?  45   ASN A HD22 1 
ATOM   465   N N    . THR A 1 80  ? 5.193   21.991  24.706 1.00 8.46  ?  46   THR A N    1 
ATOM   466   C CA   . THR A 1 80  ? 6.336   22.005  23.801 1.00 9.77  ?  46   THR A CA   1 
ATOM   467   C C    . THR A 1 80  ? 6.572   20.585  23.302 1.00 9.62  ?  46   THR A C    1 
ATOM   468   O O    . THR A 1 80  ? 5.945   19.629  23.756 1.00 8.63  ?  46   THR A O    1 
ATOM   469   C CB   . THR A 1 80  ? 7.590   22.540  24.508 1.00 9.22  ?  46   THR A CB   1 
ATOM   470   O OG1  . THR A 1 80  ? 7.809   21.782  25.693 1.00 12.00 ?  46   THR A OG1  1 
ATOM   471   C CG2  . THR A 1 80  ? 7.459   24.006  24.848 1.00 10.86 ?  46   THR A CG2  1 
ATOM   472   H H    . THR A 1 80  ? 5.288   21.436  25.356 1.00 10.16 ?  46   THR A H    1 
ATOM   473   H HA   . THR A 1 80  ? 6.156   22.582  23.042 1.00 11.73 ?  46   THR A HA   1 
ATOM   474   H HB   . THR A 1 80  ? 8.354   22.456  23.916 1.00 11.07 ?  46   THR A HB   1 
ATOM   475   H HG1  . THR A 1 80  ? 8.613   21.842  25.928 1.00 14.40 ?  46   THR A HG1  1 
ATOM   476   H HG21 . THR A 1 80  ? 8.247   24.308  25.326 1.00 13.04 ?  46   THR A HG21 1 
ATOM   477   H HG22 . THR A 1 80  ? 7.364   24.528  24.036 1.00 13.04 ?  46   THR A HG22 1 
ATOM   478   H HG23 . THR A 1 80  ? 6.678   24.149  25.406 1.00 13.04 ?  46   THR A HG23 1 
ATOM   479   N N    . ALA A 1 81  ? 7.490   20.448  22.339 1.00 8.43  ?  47   ALA A N    1 
ATOM   480   C CA   . ALA A 1 81  ? 7.764   19.149  21.745 1.00 8.90  ?  47   ALA A CA   1 
ATOM   481   C C    . ALA A 1 81  ? 8.209   18.130  22.791 1.00 8.61  ?  47   ALA A C    1 
ATOM   482   O O    . ALA A 1 81  ? 8.902   18.449  23.761 1.00 10.07 ?  47   ALA A O    1 
ATOM   483   C CB   . ALA A 1 81  ? 8.884   19.276  20.703 1.00 10.39 ?  47   ALA A CB   1 
ATOM   484   H H    . ALA A 1 81  ? 7.962   21.092  22.018 1.00 10.12 ?  47   ALA A H    1 
ATOM   485   H HA   . ALA A 1 81  ? 6.949   18.831  21.326 1.00 10.68 ?  47   ALA A HA   1 
ATOM   486   H HB1  . ALA A 1 81  ? 9.019   18.414  20.278 1.00 12.47 ?  47   ALA A HB1  1 
ATOM   487   H HB2  . ALA A 1 81  ? 8.625   19.935  20.040 1.00 12.47 ?  47   ALA A HB2  1 
ATOM   488   H HB3  . ALA A 1 81  ? 9.699   19.557  21.148 1.00 12.47 ?  47   ALA A HB3  1 
ATOM   489   N N    . TYR A 1 82  ? 7.825   16.879  22.570 1.00 8.62  ?  48   TYR A N    1 
ATOM   490   C CA   . TYR A 1 82  ? 8.329   15.774  23.371 1.00 9.14  ?  48   TYR A CA   1 
ATOM   491   C C    . TYR A 1 82  ? 9.819   15.581  23.113 1.00 11.10 ?  48   TYR A C    1 
ATOM   492   O O    . TYR A 1 82  ? 10.301  15.768  21.995 1.00 11.43 ?  48   TYR A O    1 
ATOM   493   C CB   . TYR A 1 82  ? 7.575   14.478  23.037 1.00 8.89  ?  48   TYR A CB   1 
ATOM   494   C CG   . TYR A 1 82  ? 6.104   14.608  23.364 1.00 7.97  ?  48   TYR A CG   1 
ATOM   495   C CD1  . TYR A 1 82  ? 5.645   14.422  24.663 1.00 9.12  ?  48   TYR A CD1  1 
ATOM   496   C CD2  . TYR A 1 82  ? 5.198   14.989  22.393 1.00 8.46  ?  48   TYR A CD2  1 
ATOM   497   C CE1  . TYR A 1 82  ? 4.297   14.583  24.982 1.00 7.94  ?  48   TYR A CE1  1 
ATOM   498   C CE2  . TYR A 1 82  ? 3.857   15.151  22.698 1.00 8.50  ?  48   TYR A CE2  1 
ATOM   499   C CZ   . TYR A 1 82  ? 3.420   14.972  23.993 1.00 8.13  ?  48   TYR A CZ   1 
ATOM   500   O OH   . TYR A 1 82  ? 2.076   15.132  24.296 1.00 8.61  ?  48   TYR A OH   1 
ATOM   501   H H    . TYR A 1 82  ? 7.269   16.642  21.957 1.00 10.34 ?  48   TYR A H    1 
ATOM   502   H HA   . TYR A 1 82  ? 8.194   15.966  24.312 1.00 10.97 ?  48   TYR A HA   1 
ATOM   503   H HB2  . TYR A 1 82  ? 7.664   14.287  22.090 1.00 10.67 ?  48   TYR A HB2  1 
ATOM   504   H HB3  . TYR A 1 82  ? 7.943   13.747  23.559 1.00 10.67 ?  48   TYR A HB3  1 
ATOM   505   H HD1  . TYR A 1 82  ? 6.247   14.185  25.331 1.00 10.94 ?  48   TYR A HD1  1 
ATOM   506   H HD2  . TYR A 1 82  ? 5.493   15.138  21.524 1.00 10.16 ?  48   TYR A HD2  1 
ATOM   507   H HE1  . TYR A 1 82  ? 3.996   14.431  25.848 1.00 9.52  ?  48   TYR A HE1  1 
ATOM   508   H HE2  . TYR A 1 82  ? 3.252   15.382  22.030 1.00 10.20 ?  48   TYR A HE2  1 
ATOM   509   H HH   . TYR A 1 82  ? 1.657   15.389  23.615 1.00 10.33 ?  48   TYR A HH   1 
ATOM   510   N N    . THR A 1 83  ? 10.545  15.190  24.160 1.00 10.76 ?  49   THR A N    1 
ATOM   511   C CA   . THR A 1 83  ? 11.933  14.779  23.971 1.00 11.16 ?  49   THR A CA   1 
ATOM   512   C C    . THR A 1 83  ? 11.981  13.419  23.277 1.00 12.30 ?  49   THR A C    1 
ATOM   513   O O    . THR A 1 83  ? 10.978  12.713  23.161 1.00 10.23 ?  49   THR A O    1 
ATOM   514   C CB   . THR A 1 83  ? 12.636  14.632  25.317 1.00 11.00 ?  49   THR A CB   1 
ATOM   515   O OG1  . THR A 1 83  ? 12.059  13.520  26.014 1.00 11.74 ?  49   THR A OG1  1 
ATOM   516   C CG2  . THR A 1 83  ? 12.547  15.919  26.135 1.00 12.50 ?  49   THR A CG2  1 
ATOM   517   H H    . THR A 1 83  ? 10.262  15.154  24.972 1.00 12.92 ?  49   THR A H    1 
ATOM   518   H HA   . THR A 1 83  ? 12.385  15.450  23.436 1.00 13.39 ?  49   THR A HA   1 
ATOM   519   H HB   . THR A 1 83  ? 13.583  14.466  25.189 1.00 13.20 ?  49   THR A HB   1 
ATOM   520   H HG1  . THR A 1 83  ? 12.210  13.588  26.837 1.00 14.09 ?  49   THR A HG1  1 
ATOM   521   H HG21 . THR A 1 83  ? 13.147  15.871  26.896 1.00 15.00 ?  49   THR A HG21 1 
ATOM   522   H HG22 . THR A 1 83  ? 12.797  16.679  25.586 1.00 15.00 ?  49   THR A HG22 1 
ATOM   523   H HG23 . THR A 1 83  ? 11.641  16.047  26.456 1.00 15.00 ?  49   THR A HG23 1 
ATOM   524   N N    A ASP A 1 84  ? 13.176  13.033  22.823 0.42 13.20 ?  50   ASP A N    1 
ATOM   525   N N    B ASP A 1 84  ? 13.177  13.050  22.802 0.58 13.22 ?  50   ASP A N    1 
ATOM   526   C CA   A ASP A 1 84  ? 13.313  11.721  22.200 0.42 12.21 ?  50   ASP A CA   1 
ATOM   527   C CA   B ASP A 1 84  ? 13.353  11.729  22.209 0.58 12.22 ?  50   ASP A CA   1 
ATOM   528   C C    A ASP A 1 84  ? 12.925  10.611  23.172 0.42 10.62 ?  50   ASP A C    1 
ATOM   529   C C    B ASP A 1 84  ? 12.924  10.629  23.174 0.58 10.57 ?  50   ASP A C    1 
ATOM   530   O O    A ASP A 1 84  ? 12.247  9.647   22.787 0.42 12.20 ?  50   ASP A O    1 
ATOM   531   O O    B ASP A 1 84  ? 12.218  9.687   22.781 0.58 12.17 ?  50   ASP A O    1 
ATOM   532   C CB   A ASP A 1 84  ? 14.735  11.519  21.675 0.42 13.25 ?  50   ASP A CB   1 
ATOM   533   C CB   B ASP A 1 84  ? 14.814  11.530  21.792 0.58 13.01 ?  50   ASP A CB   1 
ATOM   534   C CG   A ASP A 1 84  ? 14.900  10.195  20.953 0.42 17.55 ?  50   ASP A CG   1 
ATOM   535   C CG   B ASP A 1 84  ? 15.235  12.437  20.651 0.58 16.05 ?  50   ASP A CG   1 
ATOM   536   O OD1  A ASP A 1 84  ? 14.332  10.045  19.852 0.42 17.63 ?  50   ASP A OD1  1 
ATOM   537   O OD1  B ASP A 1 84  ? 14.376  13.123  20.060 0.58 18.78 ?  50   ASP A OD1  1 
ATOM   538   O OD2  A ASP A 1 84  ? 15.581  9.301   21.496 0.42 22.71 ?  50   ASP A OD2  1 
ATOM   539   O OD2  B ASP A 1 84  ? 16.449  12.455  20.336 0.58 21.90 ?  50   ASP A OD2  1 
ATOM   540   H H    A ASP A 1 84  ? 13.898  13.498  22.863 0.42 15.84 ?  50   ASP A H    1 
ATOM   541   H H    B ASP A 1 84  ? 13.885  13.539  22.813 0.58 15.87 ?  50   ASP A H    1 
ATOM   542   H HA   A ASP A 1 84  ? 12.716  11.675  21.437 0.42 14.65 ?  50   ASP A HA   1 
ATOM   543   H HA   B ASP A 1 84  ? 12.800  11.670  21.415 0.58 14.67 ?  50   ASP A HA   1 
ATOM   544   H HB2  A ASP A 1 84  ? 14.949  12.231  21.052 0.42 15.90 ?  50   ASP A HB2  1 
ATOM   545   H HB2  B ASP A 1 84  ? 15.387  11.719  22.551 0.58 15.61 ?  50   ASP A HB2  1 
ATOM   546   H HB3  A ASP A 1 84  ? 15.355  11.535  22.422 0.42 15.90 ?  50   ASP A HB3  1 
ATOM   547   H HB3  B ASP A 1 84  ? 14.937  10.612  21.504 0.58 15.61 ?  50   ASP A HB3  1 
ATOM   548   N N    . GLU A 1 85  ? 13.323  10.732  24.441 1.00 12.70 ?  51   GLU A N    1 
ATOM   549   C CA   . GLU A 1 85  ? 12.923  9.735   25.431 1.00 13.50 ?  51   GLU A CA   1 
ATOM   550   C C    . GLU A 1 85  ? 11.401  9.667   25.547 1.00 11.53 ?  51   GLU A C    1 
ATOM   551   O O    . GLU A 1 85  ? 10.818  8.580   25.639 1.00 12.32 ?  51   GLU A O    1 
ATOM   552   C CB   . GLU A 1 85  ? 13.545  10.064  26.796 1.00 15.14 ?  51   GLU A CB   1 
ATOM   553   C CG   . GLU A 1 85  ? 13.070  9.175   27.931 1.00 16.37 ?  51   GLU A CG   1 
ATOM   554   C CD   . GLU A 1 85  ? 13.507  9.602   29.335 1.00 23.12 ?  51   GLU A CD   1 
ATOM   555   O OE1  . GLU A 1 85  ? 13.766  10.794  29.578 1.00 20.79 ?  51   GLU A OE1  1 
ATOM   556   O OE2  . GLU A 1 85  ? 13.544  8.722   30.224 1.00 27.64 ?  51   GLU A OE2  1 
ATOM   557   H H    . GLU A 1 85  ? 13.820  11.364  24.747 1.00 15.24 ?  51   GLU A H    1 
ATOM   558   H HA   . GLU A 1 85  ? 13.252  8.867   25.152 1.00 16.19 ?  51   GLU A HA   1 
ATOM   559   H HB2  . GLU A 1 85  ? 14.508  9.966   26.729 1.00 18.17 ?  51   GLU A HB2  1 
ATOM   560   H HB3  . GLU A 1 85  ? 13.321  10.979  27.026 1.00 18.17 ?  51   GLU A HB3  1 
ATOM   561   H HG2  . GLU A 1 85  ? 12.100  9.162   27.923 1.00 19.64 ?  51   GLU A HG2  1 
ATOM   562   H HG3  . GLU A 1 85  ? 13.414  8.280   27.782 1.00 19.64 ?  51   GLU A HG3  1 
ATOM   563   N N    . GLU A 1 86  ? 10.741  10.826  25.532 1.00 10.78 ?  52   GLU A N    1 
ATOM   564   C CA   . GLU A 1 86  ? 9.282   10.845  25.636 1.00 9.76  ?  52   GLU A CA   1 
ATOM   565   C C    . GLU A 1 86  ? 8.616   10.241  24.408 1.00 9.15  ?  52   GLU A C    1 
ATOM   566   O O    . GLU A 1 86  ? 7.612   9.535   24.541 1.00 9.96  ?  52   GLU A O    1 
ATOM   567   C CB   . GLU A 1 86  ? 8.824   12.277  25.898 1.00 9.95  ?  52   GLU A CB   1 
ATOM   568   C CG   . GLU A 1 86  ? 9.182   12.779  27.306 1.00 10.75 ?  52   GLU A CG   1 
ATOM   569   C CD   . GLU A 1 86  ? 8.962   14.255  27.514 1.00 9.58  ?  52   GLU A CD   1 
ATOM   570   O OE1  . GLU A 1 86  ? 8.927   15.023  26.530 1.00 10.23 ?  52   GLU A OE1  1 
ATOM   571   O OE2  . GLU A 1 86  ? 8.854   14.654  28.701 1.00 12.99 ?  52   GLU A OE2  1 
ATOM   572   H H    . GLU A 1 86  ? 11.106  11.601  25.463 1.00 12.94 ?  52   GLU A H    1 
ATOM   573   H HA   . GLU A 1 86  ? 9.000   10.301  26.388 1.00 11.71 ?  52   GLU A HA   1 
ATOM   574   H HB2  . GLU A 1 86  ? 9.249   12.866  25.254 1.00 11.94 ?  52   GLU A HB2  1 
ATOM   575   H HB3  . GLU A 1 86  ? 7.860   12.321  25.801 1.00 11.94 ?  52   GLU A HB3  1 
ATOM   576   H HG2  . GLU A 1 86  ? 8.633   12.307  27.951 1.00 12.90 ?  52   GLU A HG2  1 
ATOM   577   H HG3  . GLU A 1 86  ? 10.120  12.597  27.470 1.00 12.90 ?  52   GLU A HG3  1 
ATOM   578   N N    . ILE A 1 87  ? 9.146   10.505  23.214 1.00 9.55  ?  53   ILE A N    1 
ATOM   579   C CA   . ILE A 1 87  ? 8.620   9.859   22.011 1.00 9.52  ?  53   ILE A CA   1 
ATOM   580   C C    . ILE A 1 87  ? 8.740   8.339   22.118 1.00 11.37 ?  53   ILE A C    1 
ATOM   581   O O    . ILE A 1 87  ? 7.807   7.603   21.761 1.00 12.23 ?  53   ILE A O    1 
ATOM   582   C CB   . ILE A 1 87  ? 9.296   10.412  20.746 1.00 10.58 ?  53   ILE A CB   1 
ATOM   583   C CG1  . ILE A 1 87  ? 8.914   11.876  20.500 1.00 10.20 ?  53   ILE A CG1  1 
ATOM   584   C CG2  . ILE A 1 87  ? 8.956   9.528   19.555 1.00 10.98 ?  53   ILE A CG2  1 
ATOM   585   C CD1  . ILE A 1 87  ? 7.450   12.123  20.230 1.00 11.98 ?  53   ILE A CD1  1 
ATOM   586   H H    . ILE A 1 87  ? 9.800   11.046  23.074 1.00 11.46 ?  53   ILE A H    1 
ATOM   587   H HA   . ILE A 1 87  ? 7.676   10.073  21.944 1.00 11.42 ?  53   ILE A HA   1 
ATOM   588   H HB   . ILE A 1 87  ? 10.257  10.397  20.876 1.00 12.69 ?  53   ILE A HB   1 
ATOM   589   H HG12 . ILE A 1 87  ? 9.155   12.392  21.286 1.00 12.23 ?  53   ILE A HG12 1 
ATOM   590   H HG13 . ILE A 1 87  ? 9.408   12.196  19.729 1.00 12.23 ?  53   ILE A HG13 1 
ATOM   591   H HG21 . ILE A 1 87  ? 9.257   9.963   18.743 1.00 13.18 ?  53   ILE A HG21 1 
ATOM   592   H HG22 . ILE A 1 87  ? 9.405   8.674   19.659 1.00 13.18 ?  53   ILE A HG22 1 
ATOM   593   H HG23 . ILE A 1 87  ? 7.996   9.396   19.524 1.00 13.18 ?  53   ILE A HG23 1 
ATOM   594   H HD11 . ILE A 1 87  ? 7.335   13.036  19.923 1.00 14.38 ?  53   ILE A HD11 1 
ATOM   595   H HD12 . ILE A 1 87  ? 7.145   11.504  19.549 1.00 14.38 ?  53   ILE A HD12 1 
ATOM   596   H HD13 . ILE A 1 87  ? 6.950   11.985  21.050 1.00 14.38 ?  53   ILE A HD13 1 
ATOM   597   N N    . ASN A 1 88  ? 9.883   7.838   22.597 1.00 11.30 ?  54   ASN A N    1 
ATOM   598   C CA   . ASN A 1 88  ? 10.047  6.396   22.751 1.00 12.67 ?  54   ASN A CA   1 
ATOM   599   C C    . ASN A 1 88  ? 9.002   5.849   23.709 1.00 13.08 ?  54   ASN A C    1 
ATOM   600   O O    . ASN A 1 88  ? 8.413   4.792   23.468 1.00 13.07 ?  54   ASN A O    1 
ATOM   601   C CB   . ASN A 1 88  ? 11.445  6.071   23.269 1.00 14.35 ?  54   ASN A CB   1 
ATOM   602   C CG   . ASN A 1 88  ? 12.527  6.326   22.256 1.00 19.61 ?  54   ASN A CG   1 
ATOM   603   O OD1  . ASN A 1 88  ? 12.280  6.414   21.061 1.00 22.97 ?  54   ASN A OD1  1 
ATOM   604   N ND2  . ASN A 1 88  ? 13.752  6.452   22.742 1.00 22.99 ?  54   ASN A ND2  1 
ATOM   605   H H    . ASN A 1 88  ? 10.565  8.304   22.835 1.00 13.55 ?  54   ASN A H    1 
ATOM   606   H HA   . ASN A 1 88  ? 9.943   5.972   21.884 1.00 15.20 ?  54   ASN A HA   1 
ATOM   607   H HB2  . ASN A 1 88  ? 11.629  6.622   24.046 1.00 17.23 ?  54   ASN A HB2  1 
ATOM   608   H HB3  . ASN A 1 88  ? 11.480  5.133   23.513 1.00 17.23 ?  54   ASN A HB3  1 
ATOM   609   H HD21 . ASN A 1 88  ? 14.413  6.599   22.211 1.00 27.58 ?  54   ASN A HD21 1 
ATOM   610   H HD22 . ASN A 1 88  ? 13.888  6.388   23.589 1.00 27.58 ?  54   ASN A HD22 1 
ATOM   611   N N    . TYR A 1 89  ? 8.748   6.571   24.797 1.00 11.08 ?  55   TYR A N    1 
ATOM   612   C CA   . TYR A 1 89  ? 7.704   6.166   25.736 1.00 10.46 ?  55   TYR A CA   1 
ATOM   613   C C    . TYR A 1 89  ? 6.340   6.127   25.057 1.00 11.19 ?  55   TYR A C    1 
ATOM   614   O O    . TYR A 1 89  ? 5.621   5.124   25.137 1.00 11.76 ?  55   TYR A O    1 
ATOM   615   C CB   . TYR A 1 89  ? 7.705   7.135   26.917 1.00 11.68 ?  55   TYR A CB   1 
ATOM   616   C CG   . TYR A 1 89  ? 6.687   6.903   27.999 1.00 11.15 ?  55   TYR A CG   1 
ATOM   617   C CD1  . TYR A 1 89  ? 6.740   5.770   28.812 1.00 12.25 ?  55   TYR A CD1  1 
ATOM   618   C CD2  . TYR A 1 89  ? 5.694   7.843   28.259 1.00 11.93 ?  55   TYR A CD2  1 
ATOM   619   C CE1  . TYR A 1 89  ? 5.823   5.575   29.815 1.00 12.39 ?  55   TYR A CE1  1 
ATOM   620   C CE2  . TYR A 1 89  ? 4.787   7.659   29.268 1.00 12.08 ?  55   TYR A CE2  1 
ATOM   621   C CZ   . TYR A 1 89  ? 4.843   6.536   30.044 1.00 12.79 ?  55   TYR A CZ   1 
ATOM   622   O OH   . TYR A 1 89  ? 3.923   6.368   31.053 1.00 13.78 ?  55   TYR A OH   1 
ATOM   623   H H    . TYR A 1 89  ? 9.161   7.293   25.014 1.00 13.30 ?  55   TYR A H    1 
ATOM   624   H HA   . TYR A 1 89  ? 7.886   5.273   26.067 1.00 12.55 ?  55   TYR A HA   1 
ATOM   625   H HB2  . TYR A 1 89  ? 8.578   7.091   27.338 1.00 14.01 ?  55   TYR A HB2  1 
ATOM   626   H HB3  . TYR A 1 89  ? 7.549   8.028   26.571 1.00 14.01 ?  55   TYR A HB3  1 
ATOM   627   H HD1  . TYR A 1 89  ? 7.406   5.137   28.671 1.00 14.70 ?  55   TYR A HD1  1 
ATOM   628   H HD2  . TYR A 1 89  ? 5.645   8.612   27.737 1.00 14.32 ?  55   TYR A HD2  1 
ATOM   629   H HE1  . TYR A 1 89  ? 5.856   4.806   30.337 1.00 14.87 ?  55   TYR A HE1  1 
ATOM   630   H HE2  . TYR A 1 89  ? 4.131   8.300   29.426 1.00 14.50 ?  55   TYR A HE2  1 
ATOM   631   H HH   . TYR A 1 89  ? 4.271   5.950   31.693 1.00 16.54 ?  55   TYR A HH   1 
ATOM   632   N N    . LEU A 1 90  ? 5.960   7.210   24.379 1.00 11.07 ?  56   LEU A N    1 
ATOM   633   C CA   . LEU A 1 90  ? 4.676   7.209   23.688 1.00 10.13 ?  56   LEU A CA   1 
ATOM   634   C C    . LEU A 1 90  ? 4.565   6.038   22.718 1.00 10.62 ?  56   LEU A C    1 
ATOM   635   O O    . LEU A 1 90  ? 3.519   5.380   22.640 1.00 10.35 ?  56   LEU A O    1 
ATOM   636   C CB   . LEU A 1 90  ? 4.482   8.525   22.946 1.00 10.61 ?  56   LEU A CB   1 
ATOM   637   C CG   . LEU A 1 90  ? 4.307   9.771   23.830 1.00 8.65  ?  56   LEU A CG   1 
ATOM   638   C CD1  . LEU A 1 90  ? 4.069   11.021  23.001 1.00 9.89  ?  56   LEU A CD1  1 
ATOM   639   C CD2  . LEU A 1 90  ? 3.161   9.552   24.811 1.00 11.94 ?  56   LEU A CD2  1 
ATOM   640   H H    . LEU A 1 90  ? 6.414   7.937   24.306 1.00 13.28 ?  56   LEU A H    1 
ATOM   641   H HA   . LEU A 1 90  ? 3.971   7.122   24.349 1.00 12.16 ?  56   LEU A HA   1 
ATOM   642   H HB2  . LEU A 1 90  ? 5.261   8.675   22.388 1.00 12.73 ?  56   LEU A HB2  1 
ATOM   643   H HB3  . LEU A 1 90  ? 3.688   8.448   22.395 1.00 12.73 ?  56   LEU A HB3  1 
ATOM   644   H HG   . LEU A 1 90  ? 5.127   9.914   24.328 1.00 10.38 ?  56   LEU A HG   1 
ATOM   645   H HD11 . LEU A 1 90  ? 4.141   11.799  23.576 1.00 11.87 ?  56   LEU A HD11 1 
ATOM   646   H HD12 . LEU A 1 90  ? 4.736   11.066  22.299 1.00 11.87 ?  56   LEU A HD12 1 
ATOM   647   H HD13 . LEU A 1 90  ? 3.182   10.978  22.612 1.00 11.87 ?  56   LEU A HD13 1 
ATOM   648   H HD21 . LEU A 1 90  ? 2.917   10.404  25.206 1.00 14.33 ?  56   LEU A HD21 1 
ATOM   649   H HD22 . LEU A 1 90  ? 2.403   9.180   24.334 1.00 14.33 ?  56   LEU A HD22 1 
ATOM   650   H HD23 . LEU A 1 90  ? 3.451   8.937   25.503 1.00 14.33 ?  56   LEU A HD23 1 
ATOM   651   N N    . ALA A 1 91  ? 5.624   5.782   21.944 1.00 10.35 ?  57   ALA A N    1 
ATOM   652   C CA   . ALA A 1 91  ? 5.586   4.738   20.924 1.00 10.48 ?  57   ALA A CA   1 
ATOM   653   C C    . ALA A 1 91  ? 5.479   3.331   21.499 1.00 11.98 ?  57   ALA A C    1 
ATOM   654   O O    . ALA A 1 91  ? 5.155   2.404   20.742 1.00 13.08 ?  57   ALA A O    1 
ATOM   655   C CB   . ALA A 1 91  ? 6.827   4.842   20.031 1.00 11.05 ?  57   ALA A CB   1 
ATOM   656   H H    . ALA A 1 91  ? 6.375   6.199   21.992 1.00 12.42 ?  57   ALA A H    1 
ATOM   657   H HA   . ALA A 1 91  ? 4.801   4.879   20.373 1.00 12.58 ?  57   ALA A HA   1 
ATOM   658   H HB1  . ALA A 1 91  ? 6.759   4.187   19.318 1.00 13.26 ?  57   ALA A HB1  1 
ATOM   659   H HB2  . ALA A 1 91  ? 6.872   5.735   19.655 1.00 13.26 ?  57   ALA A HB2  1 
ATOM   660   H HB3  . ALA A 1 91  ? 7.617   4.668   20.566 1.00 13.26 ?  57   ALA A HB3  1 
ATOM   661   N N    . SER A 1 92  ? 5.726   3.154   22.793 1.00 10.28 ?  58   SER A N    1 
ATOM   662   C CA   . SER A 1 92  ? 5.582   1.871   23.458 1.00 11.42 ?  58   SER A CA   1 
ATOM   663   C C    . SER A 1 92  ? 4.132   1.523   23.773 1.00 13.00 ?  58   SER A C    1 
ATOM   664   O O    . SER A 1 92  ? 3.862   0.389   24.183 1.00 14.43 ?  58   SER A O    1 
ATOM   665   C CB   . SER A 1 92  ? 6.408   1.828   24.748 1.00 11.58 ?  58   SER A CB   1 
ATOM   666   O OG   . SER A 1 92  ? 5.782   2.525   25.806 1.00 12.88 ?  58   SER A OG   1 
ATOM   667   H H    . SER A 1 92  ? 5.986   3.781   23.321 1.00 12.33 ?  58   SER A H    1 
ATOM   668   H HA   . SER A 1 92  ? 5.934   1.188   22.866 1.00 13.70 ?  58   SER A HA   1 
ATOM   669   H HB2  . SER A 1 92  ? 6.523   0.902   25.012 1.00 13.90 ?  58   SER A HB2  1 
ATOM   670   H HB3  . SER A 1 92  ? 7.272   2.234   24.577 1.00 13.90 ?  58   SER A HB3  1 
ATOM   671   H HG   . SER A 1 92  ? 5.763   3.348   25.636 1.00 15.45 ?  58   SER A HG   1 
ATOM   672   N N    . PHE A 1 93  ? 3.189   2.467   23.608 1.00 10.33 ?  59   PHE A N    1 
ATOM   673   C CA   . PHE A 1 93  ? 1.778   2.194   23.882 1.00 9.00  ?  59   PHE A CA   1 
ATOM   674   C C    . PHE A 1 93  ? 1.073   1.762   22.611 1.00 10.42 ?  59   PHE A C    1 
ATOM   675   O O    . PHE A 1 93  ? 1.367   2.280   21.531 1.00 11.78 ?  59   PHE A O    1 
ATOM   676   C CB   . PHE A 1 93  ? 1.094   3.451   24.413 1.00 9.73  ?  59   PHE A CB   1 
ATOM   677   C CG   . PHE A 1 93  ? 1.524   3.808   25.788 1.00 8.71  ?  59   PHE A CG   1 
ATOM   678   C CD1  . PHE A 1 93  ? 2.655   4.583   25.979 1.00 9.41  ?  59   PHE A CD1  1 
ATOM   679   C CD2  . PHE A 1 93  ? 0.843   3.343   26.887 1.00 9.25  ?  59   PHE A CD2  1 
ATOM   680   C CE1  . PHE A 1 93  ? 3.098   4.880   27.252 1.00 10.09 ?  59   PHE A CE1  1 
ATOM   681   C CE2  . PHE A 1 93  ? 1.267   3.654   28.170 1.00 9.83  ?  59   PHE A CE2  1 
ATOM   682   C CZ   . PHE A 1 93  ? 2.399   4.433   28.357 1.00 10.09 ?  59   PHE A CZ   1 
ATOM   683   H H    . PHE A 1 93  ? 3.343   3.269   23.339 1.00 12.39 ?  59   PHE A H    1 
ATOM   684   H HA   . PHE A 1 93  ? 1.702   1.486   24.540 1.00 10.80 ?  59   PHE A HA   1 
ATOM   685   H HB2  . PHE A 1 93  ? 1.309   4.196   23.830 1.00 11.68 ?  59   PHE A HB2  1 
ATOM   686   H HB3  . PHE A 1 93  ? 0.136   3.306   24.427 1.00 11.68 ?  59   PHE A HB3  1 
ATOM   687   H HD1  . PHE A 1 93  ? 3.121   4.906   25.242 1.00 11.29 ?  59   PHE A HD1  1 
ATOM   688   H HD2  . PHE A 1 93  ? 0.088   2.813   26.768 1.00 11.09 ?  59   PHE A HD2  1 
ATOM   689   H HE1  . PHE A 1 93  ? 3.871   5.384   27.367 1.00 12.11 ?  59   PHE A HE1  1 
ATOM   690   H HE2  . PHE A 1 93  ? 0.792   3.340   28.906 1.00 11.80 ?  59   PHE A HE2  1 
ATOM   691   H HZ   . PHE A 1 93  ? 2.684   4.651   29.215 1.00 12.11 ?  59   PHE A HZ   1 
ATOM   692   N N    . PRO A 1 94  ? 0.125   0.829   22.709 1.00 8.79  ?  60   PRO A N    1 
ATOM   693   C CA   . PRO A 1 94  ? -0.560  0.389   21.481 1.00 10.31 ?  60   PRO A CA   1 
ATOM   694   C C    . PRO A 1 94  ? -1.533  1.408   20.932 1.00 9.79  ?  60   PRO A C    1 
ATOM   695   O O    . PRO A 1 94  ? -1.819  1.405   19.730 1.00 9.70  ?  60   PRO A O    1 
ATOM   696   C CB   . PRO A 1 94  ? -1.277  -0.902  21.910 1.00 11.39 ?  60   PRO A CB   1 
ATOM   697   C CG   . PRO A 1 94  ? -1.386  -0.807  23.403 1.00 13.07 ?  60   PRO A CG   1 
ATOM   698   C CD   . PRO A 1 94  ? -0.122  -0.084  23.843 1.00 10.15 ?  60   PRO A CD   1 
ATOM   699   H HA   . PRO A 1 94  ? 0.098   0.177   20.801 1.00 12.37 ?  60   PRO A HA   1 
ATOM   700   H HB2  . PRO A 1 94  ? -2.155  -0.945  21.500 1.00 13.67 ?  60   PRO A HB2  1 
ATOM   701   H HB3  . PRO A 1 94  ? -0.752  -1.675  21.649 1.00 13.67 ?  60   PRO A HB3  1 
ATOM   702   H HG2  . PRO A 1 94  ? -2.178  -0.300  23.645 1.00 15.68 ?  60   PRO A HG2  1 
ATOM   703   H HG3  . PRO A 1 94  ? -1.430  -1.695  23.789 1.00 15.68 ?  60   PRO A HG3  1 
ATOM   704   H HD2  . PRO A 1 94  ? -0.270  0.410   24.664 1.00 12.17 ?  60   PRO A HD2  1 
ATOM   705   H HD3  . PRO A 1 94  ? 0.614   -0.706  23.958 1.00 12.17 ?  60   PRO A HD3  1 
ATOM   706   N N    . LEU A 1 95  ? -2.055  2.280   21.790 1.00 9.51  ?  61   LEU A N    1 
ATOM   707   C CA   . LEU A 1 95  ? -3.069  3.249   21.401 1.00 9.63  ?  61   LEU A CA   1 
ATOM   708   C C    . LEU A 1 95  ? -2.807  4.532   22.177 1.00 7.58  ?  61   LEU A C    1 
ATOM   709   O O    . LEU A 1 95  ? -2.698  4.496   23.409 1.00 8.99  ?  61   LEU A O    1 
ATOM   710   C CB   . LEU A 1 95  ? -4.459  2.696   21.711 1.00 9.85  ?  61   LEU A CB   1 
ATOM   711   C CG   . LEU A 1 95  ? -5.665  3.540   21.313 1.00 9.01  ?  61   LEU A CG   1 
ATOM   712   C CD1  . LEU A 1 95  ? -5.658  3.844   19.841 1.00 9.68  ?  61   LEU A CD1  1 
ATOM   713   C CD2  . LEU A 1 95  ? -6.935  2.793   21.721 1.00 11.42 ?  61   LEU A CD2  1 
ATOM   714   H H    . LEU A 1 95  ? -1.832  2.330   22.619 1.00 11.41 ?  61   LEU A H    1 
ATOM   715   H HA   . LEU A 1 95  ? -3.025  3.453   20.454 1.00 11.56 ?  61   LEU A HA   1 
ATOM   716   H HB2  . LEU A 1 95  ? -4.548  1.846   21.251 1.00 11.82 ?  61   LEU A HB2  1 
ATOM   717   H HB3  . LEU A 1 95  ? -4.517  2.561   22.670 1.00 11.82 ?  61   LEU A HB3  1 
ATOM   718   H HG   . LEU A 1 95  ? -5.637  4.397   21.767 1.00 10.81 ?  61   LEU A HG   1 
ATOM   719   H HD11 . LEU A 1 95  ? -6.493  4.278   19.605 1.00 11.62 ?  61   LEU A HD11 1 
ATOM   720   H HD12 . LEU A 1 95  ? -4.912  4.432   19.643 1.00 11.62 ?  61   LEU A HD12 1 
ATOM   721   H HD13 . LEU A 1 95  ? -5.566  3.014   19.348 1.00 11.62 ?  61   LEU A HD13 1 
ATOM   722   H HD21 . LEU A 1 95  ? -7.699  3.378   21.597 1.00 13.71 ?  61   LEU A HD21 1 
ATOM   723   H HD22 . LEU A 1 95  ? -7.029  2.003   21.165 1.00 13.71 ?  61   LEU A HD22 1 
ATOM   724   H HD23 . LEU A 1 95  ? -6.864  2.535   22.653 1.00 13.71 ?  61   LEU A HD23 1 
ATOM   725   N N    . ILE A 1 96  ? -2.697  5.642   21.448 1.00 8.96  ?  62   ILE A N    1 
ATOM   726   C CA   . ILE A 1 96  ? -2.342  6.949   21.998 1.00 8.50  ?  62   ILE A CA   1 
ATOM   727   C C    . ILE A 1 96  ? -3.324  7.976   21.457 1.00 9.31  ?  62   ILE A C    1 
ATOM   728   O O    . ILE A 1 96  ? -3.500  8.081   20.242 1.00 9.41  ?  62   ILE A O    1 
ATOM   729   C CB   . ILE A 1 96  ? -0.917  7.371   21.578 1.00 8.15  ?  62   ILE A CB   1 
ATOM   730   C CG1  . ILE A 1 96  ? 0.111   6.316   21.981 1.00 10.41 ?  62   ILE A CG1  1 
ATOM   731   C CG2  . ILE A 1 96  ? -0.570  8.724   22.189 1.00 10.28 ?  62   ILE A CG2  1 
ATOM   732   C CD1  . ILE A 1 96  ? 0.911   5.813   20.816 1.00 15.19 ?  62   ILE A CD1  1 
ATOM   733   H H    . ILE A 1 96  ? -2.828  5.664   20.599 1.00 10.76 ?  62   ILE A H    1 
ATOM   734   H HA   . ILE A 1 96  ? -2.405  6.911   22.965 1.00 10.20 ?  62   ILE A HA   1 
ATOM   735   H HB   . ILE A 1 96  ? -0.897  7.447   20.611 1.00 9.78  ?  62   ILE A HB   1 
ATOM   736   H HG12 . ILE A 1 96  ? 0.726   6.703   22.623 1.00 12.49 ?  62   ILE A HG12 1 
ATOM   737   H HG13 . ILE A 1 96  ? -0.351  5.560   22.378 1.00 12.49 ?  62   ILE A HG13 1 
ATOM   738   H HG21 . ILE A 1 96  ? 0.317   8.985   21.897 1.00 12.34 ?  62   ILE A HG21 1 
ATOM   739   H HG22 . ILE A 1 96  ? -1.221  9.380   21.895 1.00 12.34 ?  62   ILE A HG22 1 
ATOM   740   H HG23 . ILE A 1 96  ? -0.591  8.649   23.156 1.00 12.34 ?  62   ILE A HG23 1 
ATOM   741   H HD11 . ILE A 1 96  ? 1.614   5.231   21.143 1.00 18.23 ?  62   ILE A HD11 1 
ATOM   742   H HD12 . ILE A 1 96  ? 0.325   5.320   20.220 1.00 18.23 ?  62   ILE A HD12 1 
ATOM   743   H HD13 . ILE A 1 96  ? 1.298   6.569   20.349 1.00 18.23 ?  62   ILE A HD13 1 
ATOM   744   N N    . THR A 1 97  ? -3.949  8.753   22.343 1.00 8.24  ?  63   THR A N    1 
ATOM   745   C CA   . THR A 1 97  ? -4.695  9.939   21.927 1.00 7.24  ?  63   THR A CA   1 
ATOM   746   C C    . THR A 1 97  ? -3.862  11.178  22.191 1.00 6.55  ?  63   THR A C    1 
ATOM   747   O O    . THR A 1 97  ? -3.392  11.388  23.312 1.00 7.46  ?  63   THR A O    1 
ATOM   748   C CB   . THR A 1 97  ? -6.033  10.048  22.662 1.00 8.33  ?  63   THR A CB   1 
ATOM   749   O OG1  . THR A 1 97  ? -6.856  8.948   22.250 1.00 8.58  ?  63   THR A OG1  1 
ATOM   750   C CG2  . THR A 1 97  ? -6.735  11.359  22.365 1.00 8.30  ?  63   THR A CG2  1 
ATOM   751   H H    . THR A 1 97  ? -3.954  8.613   23.192 1.00 9.89  ?  63   THR A H    1 
ATOM   752   H HA   . THR A 1 97  ? -4.879  9.878   20.977 1.00 8.69  ?  63   THR A HA   1 
ATOM   753   H HB   . THR A 1 97  ? -5.886  10.025  23.620 1.00 10.00 ?  63   THR A HB   1 
ATOM   754   H HG1  . THR A 1 97  ? -6.869  8.359   22.849 1.00 10.30 ?  63   THR A HG1  1 
ATOM   755   H HG21 . THR A 1 97  ? -7.588  11.390  22.826 1.00 9.96  ?  63   THR A HG21 1 
ATOM   756   H HG22 . THR A 1 97  ? -6.189  12.103  22.662 1.00 9.96  ?  63   THR A HG22 1 
ATOM   757   H HG23 . THR A 1 97  ? -6.890  11.443  21.411 1.00 9.96  ?  63   THR A HG23 1 
ATOM   758   N N    . LEU A 1 98  ? -3.704  12.002  21.160 1.00 7.01  ?  64   LEU A N    1 
ATOM   759   C CA   . LEU A 1 98  ? -3.064  13.305  21.276 1.00 7.23  ?  64   LEU A CA   1 
ATOM   760   C C    . LEU A 1 98  ? -4.157  14.328  21.551 1.00 7.13  ?  64   LEU A C    1 
ATOM   761   O O    . LEU A 1 98  ? -5.021  14.568  20.700 1.00 7.50  ?  64   LEU A O    1 
ATOM   762   C CB   . LEU A 1 98  ? -2.282  13.621  20.010 1.00 7.21  ?  64   LEU A CB   1 
ATOM   763   C CG   . LEU A 1 98  ? -1.120  12.652  19.736 1.00 8.14  ?  64   LEU A CG   1 
ATOM   764   C CD1  . LEU A 1 98  ? -0.402  13.084  18.448 1.00 9.47  ?  64   LEU A CD1  1 
ATOM   765   C CD2  . LEU A 1 98  ? -0.139  12.570  20.866 1.00 9.79  ?  64   LEU A CD2  1 
ATOM   766   H H    . LEU A 1 98  ? -3.967  11.823  20.361 1.00 8.41  ?  64   LEU A H    1 
ATOM   767   H HA   . LEU A 1 98  ? -2.438  13.320  22.017 1.00 8.68  ?  64   LEU A HA   1 
ATOM   768   H HB2  . LEU A 1 98  ? -2.887  13.579  19.252 1.00 8.65  ?  64   LEU A HB2  1 
ATOM   769   H HB3  . LEU A 1 98  ? -1.910  14.513  20.088 1.00 8.65  ?  64   LEU A HB3  1 
ATOM   770   H HG   . LEU A 1 98  ? -1.490  11.761  19.637 1.00 9.76  ?  64   LEU A HG   1 
ATOM   771   H HD11 . LEU A 1 98  ? 0.318   12.461  18.264 1.00 11.37 ?  64   LEU A HD11 1 
ATOM   772   H HD12 . LEU A 1 98  ? -1.038  13.080  17.716 1.00 11.37 ?  64   LEU A HD12 1 
ATOM   773   H HD13 . LEU A 1 98  ? -0.044  13.977  18.571 1.00 11.37 ?  64   LEU A HD13 1 
ATOM   774   H HD21 . LEU A 1 98  ? 0.669   12.135  20.552 1.00 11.75 ?  64   LEU A HD21 1 
ATOM   775   H HD22 . LEU A 1 98  ? 0.067   13.468  21.170 1.00 11.75 ?  64   LEU A HD22 1 
ATOM   776   H HD23 . LEU A 1 98  ? -0.532  12.057  21.589 1.00 11.75 ?  64   LEU A HD23 1 
ATOM   777   N N    . GLU A 1 99  ? -4.110  14.916  22.753 1.00 6.25  ?  65   GLU A N    1 
ATOM   778   C CA   . GLU A 1 99  ? -5.048  15.924  23.222 1.00 6.01  ?  65   GLU A CA   1 
ATOM   779   C C    . GLU A 1 99  ? -4.899  17.239  22.468 1.00 7.00  ?  65   GLU A C    1 
ATOM   780   O O    . GLU A 1 99  ? -4.076  17.354  21.560 1.00 7.12  ?  65   GLU A O    1 
ATOM   781   C CB   . GLU A 1 99  ? -4.870  16.140  24.727 1.00 6.42  ?  65   GLU A CB   1 
ATOM   782   C CG   . GLU A 1 99  ? -5.850  15.337  25.575 1.00 7.17  ?  65   GLU A CG   1 
ATOM   783   C CD   . GLU A 1 99  ? -7.248  15.928  25.618 1.00 6.52  ?  65   GLU A CD   1 
ATOM   784   O OE1  . GLU A 1 99  ? -7.463  17.036  25.087 1.00 7.33  ?  65   GLU A OE1  1 
ATOM   785   O OE2  . GLU A 1 99  ? -8.127  15.243  26.197 1.00 7.69  ?  65   GLU A OE2  1 
ATOM   786   H H    . GLU A 1 99  ? -3.510  14.735  23.342 1.00 7.50  ?  65   GLU A H    1 
ATOM   787   H HA   . GLU A 1 99  ? -5.950  15.610  23.053 1.00 7.21  ?  65   GLU A HA   1 
ATOM   788   H HB2  . GLU A 1 99  ? -3.972  15.873  24.978 1.00 7.70  ?  65   GLU A HB2  1 
ATOM   789   H HB3  . GLU A 1 99  ? -5.005  17.079  24.927 1.00 7.70  ?  65   GLU A HB3  1 
ATOM   790   H HG2  . GLU A 1 99  ? -5.919  14.442  25.208 1.00 8.60  ?  65   GLU A HG2  1 
ATOM   791   H HG3  . GLU A 1 99  ? -5.517  15.298  26.485 1.00 8.60  ?  65   GLU A HG3  1 
ATOM   792   N N    . LYS A 1 100 ? -5.821  18.119  22.793 1.00 30.00 ?  66   LYS A N    1 
ATOM   793   C CA   . LYS A 1 100 ? -5.727  19.500  22.389 1.00 30.00 ?  66   LYS A CA   1 
ATOM   794   C C    . LYS A 1 100 ? -4.479  20.145  23.004 1.00 30.00 ?  66   LYS A C    1 
ATOM   795   O O    . LYS A 1 100 ? -3.900  19.585  23.852 1.00 30.00 ?  66   LYS A O    1 
ATOM   796   C CB   . LYS A 1 100 ? -7.014  20.236  22.865 1.00 30.00 ?  66   LYS A CB   1 
ATOM   797   C CG   . LYS A 1 100 ? -7.204  20.292  24.376 1.00 30.00 ?  66   LYS A CG   1 
ATOM   798   C CD   . LYS A 1 100 ? -8.609  20.776  24.706 1.00 30.00 ?  66   LYS A CD   1 
ATOM   799   C CE   . LYS A 1 100 ? -9.104  20.310  26.064 1.00 30.00 ?  66   LYS A CE   1 
ATOM   800   N NZ   . LYS A 1 100 ? -9.352  18.842  26.196 1.00 30.00 ?  66   LYS A NZ   1 
ATOM   801   N N    . SER A 1 101 ? -4.159  21.345  22.521 1.00 6.54  ?  67   SER A N    1 
ATOM   802   C CA   . SER A 1 101 ? -2.925  22.023  22.916 1.00 7.17  ?  67   SER A CA   1 
ATOM   803   C C    . SER A 1 101 ? -1.729  21.086  22.807 1.00 7.88  ?  67   SER A C    1 
ATOM   804   O O    . SER A 1 101 ? -1.043  20.764  23.777 1.00 7.49  ?  67   SER A O    1 
ATOM   805   C CB   . SER A 1 101 ? -3.050  22.652  24.304 1.00 7.24  ?  67   SER A CB   1 
ATOM   806   O OG   . SER A 1 101 ? -3.893  23.796  24.240 1.00 8.01  ?  67   SER A OG   1 
ATOM   807   H H    . SER A 1 101 ? -4.629  21.790  21.955 1.00 7.85  ?  67   SER A H    1 
ATOM   808   H HA   . SER A 1 101 ? -2.767  22.752  22.295 1.00 8.60  ?  67   SER A HA   1 
ATOM   809   H HB2  . SER A 1 101 ? -3.434  22.005  24.915 1.00 8.68  ?  67   SER A HB2  1 
ATOM   810   H HB3  . SER A 1 101 ? -2.170  22.920  24.614 1.00 8.68  ?  67   SER A HB3  1 
ATOM   811   H HG   . SER A 1 101 ? -4.585  23.618  23.799 1.00 9.61  ?  67   SER A HG   1 
ATOM   812   N N    . GLN A 1 102 ? -1.480  20.662  21.582 1.00 6.43  ?  68   GLN A N    1 
ATOM   813   C CA   . GLN A 1 102 ? -0.463  19.656  21.296 1.00 6.69  ?  68   GLN A CA   1 
ATOM   814   C C    . GLN A 1 102 ? 0.803   20.348  20.792 1.00 7.77  ?  68   GLN A C    1 
ATOM   815   O O    . GLN A 1 102 ? 0.955   20.608  19.594 1.00 7.71  ?  68   GLN A O    1 
ATOM   816   C CB   . GLN A 1 102 ? -0.983  18.629  20.300 1.00 6.99  ?  68   GLN A CB   1 
ATOM   817   C CG   . GLN A 1 102 ? -0.158  17.344  20.280 1.00 7.89  ?  68   GLN A CG   1 
ATOM   818   C CD   . GLN A 1 102 ? -0.142  16.573  21.586 1.00 7.96  ?  68   GLN A CD   1 
ATOM   819   O OE1  . GLN A 1 102 ? 0.920   16.084  22.026 1.00 9.76  ?  68   GLN A OE1  1 
ATOM   820   N NE2  . GLN A 1 102 ? -1.305  16.398  22.195 1.00 7.24  ?  68   GLN A NE2  1 
ATOM   821   H H    . GLN A 1 102 ? -1.893  20.946  20.883 1.00 7.72  ?  68   GLN A H    1 
ATOM   822   H HA   . GLN A 1 102 ? -0.237  19.200  22.122 1.00 8.03  ?  68   GLN A HA   1 
ATOM   823   H HB2  . GLN A 1 102 ? -1.895  18.395  20.537 1.00 8.38  ?  68   GLN A HB2  1 
ATOM   824   H HB3  . GLN A 1 102 ? -0.960  19.014  19.410 1.00 8.38  ?  68   GLN A HB3  1 
ATOM   825   H HG2  . GLN A 1 102 ? -0.522  16.755  19.600 1.00 9.46  ?  68   GLN A HG2  1 
ATOM   826   H HG3  . GLN A 1 102 ? 0.760   17.571  20.065 1.00 9.46  ?  68   GLN A HG3  1 
ATOM   827   H HE21 . GLN A 1 102 ? -2.025  16.716  21.848 1.00 8.69  ?  68   GLN A HE21 1 
ATOM   828   H HE22 . GLN A 1 102 ? -1.341  15.967  22.939 1.00 8.69  ?  68   GLN A HE22 1 
ATOM   829   N N    . ALA A 1 103 ? 1.725   20.597  21.718 1.00 7.42  ?  69   ALA A N    1 
ATOM   830   C CA   . ALA A 1 103 ? 3.067   21.126  21.424 1.00 7.30  ?  69   ALA A CA   1 
ATOM   831   C C    . ALA A 1 103 ? 3.022   22.465  20.695 1.00 8.87  ?  69   ALA A C    1 
ATOM   832   O O    . ALA A 1 103 ? 3.924   22.795  19.913 1.00 8.86  ?  69   ALA A O    1 
ATOM   833   C CB   . ALA A 1 103 ? 3.935   20.102  20.691 1.00 8.23  ?  69   ALA A CB   1 
ATOM   834   H H    . ALA A 1 103 ? 1.598   20.464  22.559 1.00 8.90  ?  69   ALA A H    1 
ATOM   835   H HA   . ALA A 1 103 ? 3.506   21.303  22.271 1.00 8.75  ?  69   ALA A HA   1 
ATOM   836   H HB1  . ALA A 1 103 ? 4.769   20.523  20.431 1.00 9.88  ?  69   ALA A HB1  1 
ATOM   837   H HB2  . ALA A 1 103 ? 4.113   19.355  21.284 1.00 9.88  ?  69   ALA A HB2  1 
ATOM   838   H HB3  . ALA A 1 103 ? 3.461   19.792  19.903 1.00 9.88  ?  69   ALA A HB3  1 
ATOM   839   N N    . GLN A 1 104 ? 1.996   23.277  20.956 1.00 8.33  ?  70   GLN A N    1 
ATOM   840   C CA   . GLN A 1 104 ? 1.786   24.503  20.199 1.00 8.01  ?  70   GLN A CA   1 
ATOM   841   C C    . GLN A 1 104 ? 2.830   25.568  20.479 1.00 10.06 ?  70   GLN A C    1 
ATOM   842   O O    . GLN A 1 104 ? 2.989   26.484  19.658 1.00 10.23 ?  70   GLN A O    1 
ATOM   843   C CB   . GLN A 1 104 ? 0.381   25.055  20.472 1.00 8.86  ?  70   GLN A CB   1 
ATOM   844   C CG   . GLN A 1 104 ? 0.192   25.782  21.799 1.00 9.89  ?  70   GLN A CG   1 
ATOM   845   C CD   . GLN A 1 104 ? 0.176   24.880  23.004 1.00 10.17 ?  70   GLN A CD   1 
ATOM   846   O OE1  . GLN A 1 104 ? -0.018  23.663  22.892 1.00 10.40 ?  70   GLN A OE1  1 
ATOM   847   N NE2  . GLN A 1 104 ? 0.386   25.456  24.165 1.00 10.57 ?  70   GLN A NE2  1 
ATOM   848   H H    . GLN A 1 104 ? 1.409   23.138  21.568 1.00 9.99  ?  70   GLN A H    1 
ATOM   849   H HA   . GLN A 1 104 ? 1.848   24.288  19.255 1.00 9.62  ?  70   GLN A HA   1 
ATOM   850   H HB2  . GLN A 1 104 ? 0.160   25.684  19.767 1.00 10.63 ?  70   GLN A HB2  1 
ATOM   851   H HB3  . GLN A 1 104 ? -0.243  24.312  20.461 1.00 10.63 ?  70   GLN A HB3  1 
ATOM   852   H HG2  . GLN A 1 104 ? 0.920   26.412  21.914 1.00 11.87 ?  70   GLN A HG2  1 
ATOM   853   H HG3  . GLN A 1 104 ? -0.655  26.255  21.776 1.00 11.87 ?  70   GLN A HG3  1 
ATOM   854   H HE21 . GLN A 1 104 ? 0.523   26.304  24.206 1.00 12.69 ?  70   GLN A HE21 1 
ATOM   855   H HE22 . GLN A 1 104 ? 0.387   24.985  24.885 1.00 12.69 ?  70   GLN A HE22 1 
ATOM   856   N N    . ASN A 1 105 ? 3.528   25.498  21.604 1.00 8.26  ?  71   ASN A N    1 
ATOM   857   C CA   . ASN A 1 105 ? 4.559   26.493  21.879 1.00 9.53  ?  71   ASN A CA   1 
ATOM   858   C C    . ASN A 1 105 ? 5.880   26.153  21.213 1.00 10.92 ?  71   ASN A C    1 
ATOM   859   O O    . ASN A 1 105 ? 6.785   26.993  21.236 1.00 14.63 ?  71   ASN A O    1 
ATOM   860   C CB   . ASN A 1 105 ? 4.733   26.715  23.377 1.00 9.91  ?  71   ASN A CB   1 
ATOM   861   C CG   . ASN A 1 105 ? 3.540   27.415  24.003 1.00 11.63 ?  71   ASN A CG   1 
ATOM   862   O OD1  . ASN A 1 105 ? 2.685   27.947  23.300 1.00 14.95 ?  71   ASN A OD1  1 
ATOM   863   N ND2  . ASN A 1 105 ? 3.468   27.383  25.349 1.00 13.52 ?  71   ASN A ND2  1 
ATOM   864   H H    . ASN A 1 105 ? 3.427   24.898  22.212 1.00 9.91  ?  71   ASN A H    1 
ATOM   865   H HA   . ASN A 1 105 ? 4.269   27.349  21.526 1.00 11.44 ?  71   ASN A HA   1 
ATOM   866   H HB2  . ASN A 1 105 ? 4.841   25.856  23.814 1.00 11.89 ?  71   ASN A HB2  1 
ATOM   867   H HB3  . ASN A 1 105 ? 5.517   27.265  23.527 1.00 11.89 ?  71   ASN A HB3  1 
ATOM   868   H HD21 . ASN A 1 105 ? 2.812   27.765  25.753 1.00 16.22 ?  71   ASN A HD21 1 
ATOM   869   H HD22 . ASN A 1 105 ? 4.078   26.981  25.803 1.00 16.22 ?  71   ASN A HD22 1 
ATOM   870   N N    . THR A 1 106 ? 6.001   24.977  20.603 1.00 9.63  ?  72   THR A N    1 
ATOM   871   C CA   . THR A 1 106 ? 7.117   24.643  19.722 1.00 9.50  ?  72   THR A CA   1 
ATOM   872   C C    . THR A 1 106 ? 6.735   24.804  18.258 1.00 10.17 ?  72   THR A C    1 
ATOM   873   O O    . THR A 1 106 ? 7.472   25.423  17.487 1.00 11.97 ?  72   THR A O    1 
ATOM   874   C CB   . THR A 1 106 ? 7.609   23.217  19.963 1.00 9.65  ?  72   THR A CB   1 
ATOM   875   O OG1  . THR A 1 106 ? 7.998   23.072  21.327 1.00 9.99  ?  72   THR A OG1  1 
ATOM   876   C CG2  . THR A 1 106 ? 8.812   22.890  19.060 1.00 10.05 ?  72   THR A CG2  1 
ATOM   877   H H    . THR A 1 106 ? 5.434   24.337  20.687 1.00 11.56 ?  72   THR A H    1 
ATOM   878   H HA   . THR A 1 106 ? 7.856   25.237  19.928 1.00 11.40 ?  72   THR A HA   1 
ATOM   879   H HB   . THR A 1 106 ? 6.894   22.595  19.757 1.00 11.58 ?  72   THR A HB   1 
ATOM   880   H HG1  . THR A 1 106 ? 8.394   23.765  21.588 1.00 11.99 ?  72   THR A HG1  1 
ATOM   881   H HG21 . THR A 1 106 ? 9.172   22.019  19.289 1.00 12.05 ?  72   THR A HG21 1 
ATOM   882   H HG22 . THR A 1 106 ? 8.537   22.883  18.130 1.00 12.05 ?  72   THR A HG22 1 
ATOM   883   H HG23 . THR A 1 106 ? 9.506   23.558  19.178 1.00 12.05 ?  72   THR A HG23 1 
ATOM   884   N N    . TYR A 1 107 ? 5.570   24.289  17.862 1.00 8.93  ?  73   TYR A N    1 
ATOM   885   C CA   . TYR A 1 107 ? 5.164   24.202  16.469 1.00 9.17  ?  73   TYR A CA   1 
ATOM   886   C C    . TYR A 1 107 ? 4.162   25.270  16.065 1.00 9.60  ?  73   TYR A C    1 
ATOM   887   O O    . TYR A 1 107 ? 3.765   25.298  14.900 1.00 13.08 ?  73   TYR A O    1 
ATOM   888   C CB   . TYR A 1 107 ? 4.641   22.786  16.152 1.00 10.63 ?  73   TYR A CB   1 
ATOM   889   C CG   . TYR A 1 107 ? 5.707   21.744  16.366 1.00 9.76  ?  73   TYR A CG   1 
ATOM   890   C CD1  . TYR A 1 107 ? 6.699   21.541  15.419 1.00 11.67 ?  73   TYR A CD1  1 
ATOM   891   C CD2  . TYR A 1 107 ? 5.739   20.973  17.510 1.00 10.63 ?  73   TYR A CD2  1 
ATOM   892   C CE1  . TYR A 1 107 ? 7.698   20.612  15.627 1.00 12.52 ?  73   TYR A CE1  1 
ATOM   893   C CE2  . TYR A 1 107 ? 6.741   20.056  17.721 1.00 11.54 ?  73   TYR A CE2  1 
ATOM   894   C CZ   . TYR A 1 107 ? 7.710   19.880  16.772 1.00 11.83 ?  73   TYR A CZ   1 
ATOM   895   O OH   . TYR A 1 107 ? 8.723   18.957  16.988 1.00 15.00 ?  73   TYR A OH   1 
ATOM   896   H H    . TYR A 1 107 ? 4.981   23.974  18.405 1.00 10.72 ?  73   TYR A H    1 
ATOM   897   H HA   . TYR A 1 107 ? 5.942   24.338  15.907 1.00 11.01 ?  73   TYR A HA   1 
ATOM   898   H HB2  . TYR A 1 107 ? 3.893   22.583  16.736 1.00 12.76 ?  73   TYR A HB2  1 
ATOM   899   H HB3  . TYR A 1 107 ? 4.358   22.749  15.225 1.00 12.76 ?  73   TYR A HB3  1 
ATOM   900   H HD1  . TYR A 1 107 ? 6.691   22.037  14.632 1.00 14.01 ?  73   TYR A HD1  1 
ATOM   901   H HD2  . TYR A 1 107 ? 5.071   21.075  18.150 1.00 12.76 ?  73   TYR A HD2  1 
ATOM   902   H HE1  . TYR A 1 107 ? 8.360   20.488  14.986 1.00 15.03 ?  73   TYR A HE1  1 
ATOM   903   H HE2  . TYR A 1 107 ? 6.760   19.556  18.505 1.00 13.85 ?  73   TYR A HE2  1 
ATOM   904   H HH   . TYR A 1 107 ? 8.558   18.506  17.677 1.00 18.00 ?  73   TYR A HH   1 
ATOM   905   N N    . GLY A 1 108 ? 3.791   26.173  16.957 1.00 9.91  ?  74   GLY A N    1 
ATOM   906   C CA   . GLY A 1 108 ? 2.917   27.283  16.635 1.00 9.09  ?  74   GLY A CA   1 
ATOM   907   C C    . GLY A 1 108 ? 1.427   27.001  16.734 1.00 11.10 ?  74   GLY A C    1 
ATOM   908   O O    . GLY A 1 108 ? 0.649   27.943  16.885 1.00 15.11 ?  74   GLY A O    1 
ATOM   909   H H    . GLY A 1 108 ? 4.040   26.163  17.781 1.00 11.89 ?  74   GLY A H    1 
ATOM   910   H HA2  . GLY A 1 108 ? 3.116   28.016  17.239 1.00 10.91 ?  74   GLY A HA2  1 
ATOM   911   H HA3  . GLY A 1 108 ? 3.101   27.565  15.725 1.00 10.91 ?  74   GLY A HA3  1 
ATOM   912   N N    . SER A 1 109 ? 1.011   25.743  16.639 1.00 8.29  ?  75   SER A N    1 
ATOM   913   C CA   . SER A 1 109 ? -0.398  25.372  16.621 1.00 8.02  ?  75   SER A CA   1 
ATOM   914   C C    . SER A 1 109 ? -0.494  23.903  16.977 1.00 8.02  ?  75   SER A C    1 
ATOM   915   O O    . SER A 1 109 ? 0.448   23.128  16.781 1.00 7.71  ?  75   SER A O    1 
ATOM   916   C CB   . SER A 1 109 ? -1.035  25.570  15.245 1.00 9.19  ?  75   SER A CB   1 
ATOM   917   O OG   . SER A 1 109 ? -0.425  24.741  14.258 1.00 9.56  ?  75   SER A OG   1 
ATOM   918   H H    . SER A 1 109 ? 1.540   25.067  16.581 1.00 9.95  ?  75   SER A H    1 
ATOM   919   H HA   . SER A 1 109 ? -0.869  25.918  17.269 1.00 9.63  ?  75   SER A HA   1 
ATOM   920   H HB2  . SER A 1 109 ? -1.977  25.347  15.302 1.00 11.02 ?  75   SER A HB2  1 
ATOM   921   H HB3  . SER A 1 109 ? -0.930  26.498  14.983 1.00 11.02 ?  75   SER A HB3  1 
ATOM   922   H HG   . SER A 1 109 ? 0.308   25.073  14.016 1.00 11.47 ?  75   SER A HG   1 
ATOM   923   N N    . THR A 1 110 ? -1.679  23.517  17.442 1.00 7.33  ?  76   THR A N    1 
ATOM   924   C CA   . THR A 1 110 ? -1.956  22.104  17.683 1.00 7.22  ?  76   THR A CA   1 
ATOM   925   C C    . THR A 1 110 ? -1.932  21.301  16.396 1.00 7.51  ?  76   THR A C    1 
ATOM   926   O O    . THR A 1 110 ? -1.487  20.148  16.392 1.00 7.84  ?  76   THR A O    1 
ATOM   927   C CB   . THR A 1 110 ? -3.309  21.983  18.377 1.00 7.46  ?  76   THR A CB   1 
ATOM   928   O OG1  . THR A 1 110 ? -3.102  22.456  19.710 1.00 7.97  ?  76   THR A OG1  1 
ATOM   929   C CG2  . THR A 1 110 ? -3.817  20.563  18.412 1.00 7.64  ?  76   THR A CG2  1 
ATOM   930   H H    . THR A 1 110 ? -2.332  24.046  17.625 1.00 8.80  ?  76   THR A H    1 
ATOM   931   H HA   . THR A 1 110 ? -1.272  21.732  18.261 1.00 8.66  ?  76   THR A HA   1 
ATOM   932   H HB   . THR A 1 110 ? -3.987  22.489  17.903 1.00 8.96  ?  76   THR A HB   1 
ATOM   933   H HG1  . THR A 1 110 ? -3.839  22.643  20.066 1.00 9.56  ?  76   THR A HG1  1 
ATOM   934   H HG21 . THR A 1 110 ? -4.632  20.516  18.936 1.00 9.17  ?  76   THR A HG21 1 
ATOM   935   H HG22 . THR A 1 110 ? -4.004  20.255  17.511 1.00 9.17  ?  76   THR A HG22 1 
ATOM   936   H HG23 . THR A 1 110 ? -3.151  19.982  18.812 1.00 9.17  ?  76   THR A HG23 1 
ATOM   937   N N    . GLU A 1 111 ? -2.392  21.874  15.292 1.00 7.48  ?  77   GLU A N    1 
ATOM   938   C CA   . GLU A 1 111 ? -2.391  21.096  14.056 1.00 8.02  ?  77   GLU A CA   1 
ATOM   939   C C    . GLU A 1 111 ? -0.963  20.688  13.688 1.00 7.50  ?  77   GLU A C    1 
ATOM   940   O O    . GLU A 1 111 ? -0.694  19.517  13.400 1.00 8.68  ?  77   GLU A O    1 
ATOM   941   C CB   . GLU A 1 111 ? -3.069  21.876  12.931 1.00 8.52  ?  77   GLU A CB   1 
ATOM   942   C CG   . GLU A 1 111 ? -4.539  22.186  13.155 1.00 8.59  ?  77   GLU A CG   1 
ATOM   943   C CD   . GLU A 1 111 ? -4.799  23.521  13.802 1.00 8.12  ?  77   GLU A CD   1 
ATOM   944   O OE1  . GLU A 1 111 ? -3.965  24.019  14.574 1.00 8.61  ?  77   GLU A OE1  1 
ATOM   945   O OE2  . GLU A 1 111 ? -5.883  24.105  13.546 1.00 8.30  ?  77   GLU A OE2  1 
ATOM   946   H H    . GLU A 1 111 ? -2.697  22.675  15.231 1.00 8.97  ?  77   GLU A H    1 
ATOM   947   H HA   . GLU A 1 111 ? -2.910  20.286  14.182 1.00 9.62  ?  77   GLU A HA   1 
ATOM   948   H HB2  . GLU A 1 111 ? -2.608  22.723  12.824 1.00 10.23 ?  77   GLU A HB2  1 
ATOM   949   H HB3  . GLU A 1 111 ? -3.003  21.357  12.115 1.00 10.23 ?  77   GLU A HB3  1 
ATOM   950   H HG2  . GLU A 1 111 ? -4.991  22.183  12.297 1.00 10.30 ?  77   GLU A HG2  1 
ATOM   951   H HG3  . GLU A 1 111 ? -4.916  21.503  13.731 1.00 10.30 ?  77   GLU A HG3  1 
ATOM   952   N N    . GLU A 1 112 ? -0.025  21.640  13.719 1.00 7.99  ?  78   GLU A N    1 
ATOM   953   C CA   . GLU A 1 112 ? 1.364   21.316  13.388 1.00 7.68  ?  78   GLU A CA   1 
ATOM   954   C C    . GLU A 1 112 ? 2.042   20.497  14.475 1.00 8.57  ?  78   GLU A C    1 
ATOM   955   O O    . GLU A 1 112 ? 2.845   19.616  14.175 1.00 9.08  ?  78   GLU A O    1 
ATOM   956   C CB   . GLU A 1 112 ? 2.156   22.580  13.055 1.00 9.73  ?  78   GLU A CB   1 
ATOM   957   C CG   . GLU A 1 112 ? 1.625   23.295  11.794 1.00 13.34 ?  78   GLU A CG   1 
ATOM   958   C CD   . GLU A 1 112 ? 1.745   22.486  10.505 1.00 17.19 ?  78   GLU A CD   1 
ATOM   959   O OE1  . GLU A 1 112 ? 2.519   21.518  10.454 1.00 17.32 ?  78   GLU A OE1  1 
ATOM   960   O OE2  . GLU A 1 112 ? 1.037   22.838  9.529  1.00 21.51 ?  78   GLU A OE2  1 
ATOM   961   H H    . GLU A 1 112 ? -0.163  22.464  13.924 1.00 9.58  ?  78   GLU A H    1 
ATOM   962   H HA   . GLU A 1 112 ? 1.358   20.767  12.588 1.00 9.21  ?  78   GLU A HA   1 
ATOM   963   H HB2  . GLU A 1 112 ? 2.093   23.198  13.800 1.00 11.67 ?  78   GLU A HB2  1 
ATOM   964   H HB3  . GLU A 1 112 ? 3.083   22.341  12.899 1.00 11.67 ?  78   GLU A HB3  1 
ATOM   965   H HG2  . GLU A 1 112 ? 0.686   23.497  11.925 1.00 16.00 ?  78   GLU A HG2  1 
ATOM   966   H HG3  . GLU A 1 112 ? 2.127   24.116  11.671 1.00 16.00 ?  78   GLU A HG3  1 
ATOM   967   N N    . GLY A 1 113 ? 1.736   20.756  15.743 1.00 8.02  ?  79   GLY A N    1 
ATOM   968   C CA   . GLY A 1 113 ? 2.317   19.957  16.806 1.00 8.82  ?  79   GLY A CA   1 
ATOM   969   C C    . GLY A 1 113 ? 1.865   18.515  16.755 1.00 7.15  ?  79   GLY A C    1 
ATOM   970   O O    . GLY A 1 113 ? 2.626   17.600  17.089 1.00 8.55  ?  79   GLY A O    1 
ATOM   971   H H    . GLY A 1 113 ? 1.203   21.378  16.007 1.00 9.62  ?  79   GLY A H    1 
ATOM   972   H HA2  . GLY A 1 113 ? 3.284   19.978  16.731 1.00 10.58 ?  79   GLY A HA2  1 
ATOM   973   H HA3  . GLY A 1 113 ? 2.060   20.329  17.664 1.00 10.58 ?  79   GLY A HA3  1 
ATOM   974   N N    . THR A 1 114 ? 0.613   18.294  16.361 1.00 7.49  ?  80   THR A N    1 
ATOM   975   C CA   . THR A 1 114 ? 0.099   16.939  16.199 1.00 8.08  ?  80   THR A CA   1 
ATOM   976   C C    . THR A 1 114 ? 0.835   16.219  15.076 1.00 8.80  ?  80   THR A C    1 
ATOM   977   O O    . THR A 1 114 ? 1.251   15.069  15.228 1.00 8.64  ?  80   THR A O    1 
ATOM   978   C CB   . THR A 1 114 ? -1.409  17.006  15.921 1.00 8.96  ?  80   THR A CB   1 
ATOM   979   O OG1  . THR A 1 114 ? -2.067  17.568  17.063 1.00 7.90  ?  80   THR A OG1  1 
ATOM   980   C CG2  . THR A 1 114 ? -2.011  15.652  15.635 1.00 8.85  ?  80   THR A CG2  1 
ATOM   981   H H    . THR A 1 114 ? 0.041   18.911  16.182 1.00 8.99  ?  80   THR A H    1 
ATOM   982   H HA   . THR A 1 114 ? 0.236   16.432  17.015 1.00 9.70  ?  80   THR A HA   1 
ATOM   983   H HB   . THR A 1 114 ? -1.547  17.553  15.132 1.00 10.75 ?  80   THR A HB   1 
ATOM   984   H HG1  . THR A 1 114 ? -2.004  18.405  17.047 1.00 9.48  ?  80   THR A HG1  1 
ATOM   985   H HG21 . THR A 1 114 ? -2.951  15.747  15.413 1.00 10.62 ?  80   THR A HG21 1 
ATOM   986   H HG22 . THR A 1 114 ? -1.552  15.236  14.888 1.00 10.62 ?  80   THR A HG22 1 
ATOM   987   H HG23 . THR A 1 114 ? -1.927  15.080  16.414 1.00 10.62 ?  80   THR A HG23 1 
ATOM   988   N N    . LEU A 1 115 ? 0.994   16.886  13.931 1.00 8.64  ?  81   LEU A N    1 
ATOM   989   C CA   . LEU A 1 115 ? 1.689   16.263  12.806 1.00 9.22  ?  81   LEU A CA   1 
ATOM   990   C C    . LEU A 1 115 ? 3.113   15.884  13.194 1.00 8.16  ?  81   LEU A C    1 
ATOM   991   O O    . LEU A 1 115 ? 3.573   14.772  12.883 1.00 9.46  ?  81   LEU A O    1 
ATOM   992   C CB   . LEU A 1 115 ? 1.672   17.189  11.589 1.00 9.93  ?  81   LEU A CB   1 
ATOM   993   C CG   . LEU A 1 115 ? 0.296   17.394  10.937 1.00 10.70 ?  81   LEU A CG   1 
ATOM   994   C CD1  . LEU A 1 115 ? 0.384   18.477  9.893  1.00 12.95 ?  81   LEU A CD1  1 
ATOM   995   C CD2  . LEU A 1 115 ? -0.228  16.106  10.325 1.00 10.32 ?  81   LEU A CD2  1 
ATOM   996   H H    . LEU A 1 115 ? 0.714   17.686  13.782 1.00 10.37 ?  81   LEU A H    1 
ATOM   997   H HA   . LEU A 1 115 ? 1.221   15.452  12.553 1.00 11.06 ?  81   LEU A HA   1 
ATOM   998   H HB2  . LEU A 1 115 ? 1.996   18.061  11.864 1.00 11.92 ?  81   LEU A HB2  1 
ATOM   999   H HB3  . LEU A 1 115 ? 2.260   16.816  10.914 1.00 11.92 ?  81   LEU A HB3  1 
ATOM   1000  H HG   . LEU A 1 115 ? -0.338  17.664  11.620 1.00 12.83 ?  81   LEU A HG   1 
ATOM   1001  H HD11 . LEU A 1 115 ? -0.510  18.690  9.582  1.00 15.54 ?  81   LEU A HD11 1 
ATOM   1002  H HD12 . LEU A 1 115 ? 0.793   19.264  10.287 1.00 15.54 ?  81   LEU A HD12 1 
ATOM   1003  H HD13 . LEU A 1 115 ? 0.925   18.159  9.153  1.00 15.54 ?  81   LEU A HD13 1 
ATOM   1004  H HD21 . LEU A 1 115 ? -0.991  16.311  9.763  1.00 12.39 ?  81   LEU A HD21 1 
ATOM   1005  H HD22 . LEU A 1 115 ? 0.475   15.701  9.794  1.00 12.39 ?  81   LEU A HD22 1 
ATOM   1006  H HD23 . LEU A 1 115 ? -0.493  15.503  11.037 1.00 12.39 ?  81   LEU A HD23 1 
ATOM   1007  N N    . ALA A 1 116 ? 3.815   16.774  13.900 1.00 8.99  ?  82   ALA A N    1 
ATOM   1008  C CA   . ALA A 1 116 ? 5.204   16.494  14.259 1.00 8.69  ?  82   ALA A CA   1 
ATOM   1009  C C    . ALA A 1 116 ? 5.289   15.366  15.286 1.00 10.26 ?  82   ALA A C    1 
ATOM   1010  O O    . ALA A 1 116 ? 6.156   14.489  15.206 1.00 10.57 ?  82   ALA A O    1 
ATOM   1011  C CB   . ALA A 1 116 ? 5.887   17.758  14.774 1.00 10.28 ?  82   ALA A CB   1 
ATOM   1012  H H    . ALA A 1 116 ? 3.516   17.531  14.178 1.00 10.79 ?  82   ALA A H    1 
ATOM   1013  H HA   . ALA A 1 116 ? 5.682   16.211  13.464 1.00 10.43 ?  82   ALA A HA   1 
ATOM   1014  H HB1  . ALA A 1 116 ? 6.795   17.541  15.038 1.00 12.34 ?  82   ALA A HB1  1 
ATOM   1015  H HB2  . ALA A 1 116 ? 5.898   18.421  14.067 1.00 12.34 ?  82   ALA A HB2  1 
ATOM   1016  H HB3  . ALA A 1 116 ? 5.393   18.095  15.537 1.00 12.34 ?  82   ALA A HB3  1 
ATOM   1017  N N    . THR A 1 117 ? 4.392   15.360  16.267 1.00 9.56  ?  83   THR A N    1 
ATOM   1018  C CA   . THR A 1 117 ? 4.432   14.318  17.276 1.00 8.25  ?  83   THR A CA   1 
ATOM   1019  C C    . THR A 1 117 ? 4.107   12.963  16.667 1.00 7.99  ?  83   THR A C    1 
ATOM   1020  O O    . THR A 1 117 ? 4.791   11.965  16.936 1.00 9.19  ?  83   THR A O    1 
ATOM   1021  C CB   . THR A 1 117 ? 3.447   14.682  18.389 1.00 8.79  ?  83   THR A CB   1 
ATOM   1022  O OG1  . THR A 1 117 ? 3.817   15.922  19.005 1.00 9.08  ?  83   THR A OG1  1 
ATOM   1023  C CG2  . THR A 1 117 ? 3.419   13.620  19.439 1.00 9.76  ?  83   THR A CG2  1 
ATOM   1024  H H    . THR A 1 117 ? 3.763   15.938  16.367 1.00 11.48 ?  83   THR A H    1 
ATOM   1025  H HA   . THR A 1 117 ? 5.320   14.255  17.659 1.00 9.90  ?  83   THR A HA   1 
ATOM   1026  H HB   . THR A 1 117 ? 2.563   14.767  17.999 1.00 10.55 ?  83   THR A HB   1 
ATOM   1027  H HG1  . THR A 1 117 ? 3.905   16.518  18.420 1.00 10.90 ?  83   THR A HG1  1 
ATOM   1028  H HG21 . THR A 1 117 ? 2.897   13.919  20.200 1.00 11.72 ?  83   THR A HG21 1 
ATOM   1029  H HG22 . THR A 1 117 ? 3.019   12.811  19.082 1.00 11.72 ?  83   THR A HG22 1 
ATOM   1030  H HG23 . THR A 1 117 ? 4.321   13.421  19.734 1.00 11.72 ?  83   THR A HG23 1 
ATOM   1031  N N    . ALA A 1 118 ? 3.052   12.902  15.840 1.00 8.85  ?  84   ALA A N    1 
ATOM   1032  C CA   . ALA A 1 118 ? 2.655   11.631  15.247 1.00 8.49  ?  84   ALA A CA   1 
ATOM   1033  C C    . ALA A 1 118 ? 3.749   11.086  14.338 1.00 9.06  ?  84   ALA A C    1 
ATOM   1034  O O    . ALA A 1 118 ? 4.006   9.879   14.331 1.00 9.17  ?  84   ALA A O    1 
ATOM   1035  C CB   . ALA A 1 118 ? 1.337   11.796  14.483 1.00 10.29 ?  84   ALA A CB   1 
ATOM   1036  H H    . ALA A 1 118 ? 2.562   13.572  15.615 1.00 10.62 ?  84   ALA A H    1 
ATOM   1037  H HA   . ALA A 1 118 ? 2.507   10.983  15.953 1.00 10.19 ?  84   ALA A HA   1 
ATOM   1038  H HB1  . ALA A 1 118 ? 1.016   10.921  14.214 1.00 12.35 ?  84   ALA A HB1  1 
ATOM   1039  H HB2  . ALA A 1 118 ? 0.687   12.222  15.064 1.00 12.35 ?  84   ALA A HB2  1 
ATOM   1040  H HB3  . ALA A 1 118 ? 1.493   12.347  13.700 1.00 12.35 ?  84   ALA A HB3  1 
ATOM   1041  N N    A SER A 1 119 ? 4.398   11.954  13.558 0.61 8.94  ?  85   SER A N    1 
ATOM   1042  N N    B SER A 1 119 ? 4.412   11.953  13.568 0.39 8.98  ?  85   SER A N    1 
ATOM   1043  C CA   A SER A 1 119 ? 5.488   11.487  12.710 0.61 10.35 ?  85   SER A CA   1 
ATOM   1044  C CA   B SER A 1 119 ? 5.480   11.468  12.698 0.39 10.34 ?  85   SER A CA   1 
ATOM   1045  C C    A SER A 1 119 ? 6.584   10.854  13.557 0.61 10.30 ?  85   SER A C    1 
ATOM   1046  C C    B SER A 1 119 ? 6.624   10.884  13.520 0.39 10.33 ?  85   SER A C    1 
ATOM   1047  O O    A SER A 1 119 ? 7.076   9.761   13.258 0.61 11.15 ?  85   SER A O    1 
ATOM   1048  O O    B SER A 1 119 ? 7.191   9.847   13.161 0.39 11.13 ?  85   SER A O    1 
ATOM   1049  C CB   A SER A 1 119 ? 6.054   12.655  11.915 0.61 10.75 ?  85   SER A CB   1 
ATOM   1050  C CB   B SER A 1 119 ? 5.968   12.586  11.780 0.39 11.09 ?  85   SER A CB   1 
ATOM   1051  O OG   A SER A 1 119 ? 7.247   12.252  11.269 0.61 12.55 ?  85   SER A OG   1 
ATOM   1052  O OG   B SER A 1 119 ? 6.753   13.539  12.466 0.39 12.34 ?  85   SER A OG   1 
ATOM   1053  H H    A SER A 1 119 ? 4.229   12.795  13.505 0.61 10.72 ?  85   SER A H    1 
ATOM   1054  H H    B SER A 1 119 ? 4.266   12.800  13.533 0.39 10.77 ?  85   SER A H    1 
ATOM   1055  H HA   A SER A 1 119 ? 5.149   10.825  12.087 0.61 12.43 ?  85   SER A HA   1 
ATOM   1056  H HA   B SER A 1 119 ? 5.132   10.763  12.130 0.39 12.41 ?  85   SER A HA   1 
ATOM   1057  H HB2  A SER A 1 119 ? 5.406   12.934  11.248 0.61 12.90 ?  85   SER A HB2  1 
ATOM   1058  H HB2  B SER A 1 119 ? 6.504   12.195  11.072 0.39 13.30 ?  85   SER A HB2  1 
ATOM   1059  H HB3  A SER A 1 119 ? 6.247   13.390  12.517 0.61 12.90 ?  85   SER A HB3  1 
ATOM   1060  H HB3  B SER A 1 119 ? 5.196   13.036  11.401 0.39 13.30 ?  85   SER A HB3  1 
ATOM   1061  H HG   A SER A 1 119 ? 7.548   12.882  10.801 0.61 15.07 ?  85   SER A HG   1 
ATOM   1062  H HG   B SER A 1 119 ? 6.336   13.826  13.136 0.39 14.80 ?  85   SER A HG   1 
ATOM   1063  N N    . ALA A 1 120 ? 6.970   11.527  14.633 1.00 9.40  ?  86   ALA A N    1 
ATOM   1064  C CA   . ALA A 1 120 ? 8.038   11.014  15.484 1.00 10.21 ?  86   ALA A CA   1 
ATOM   1065  C C    . ALA A 1 120 ? 7.656   9.690   16.136 1.00 11.02 ?  86   ALA A C    1 
ATOM   1066  O O    . ALA A 1 120 ? 8.473   8.759   16.191 1.00 11.77 ?  86   ALA A O    1 
ATOM   1067  C CB   . ALA A 1 120 ? 8.429   12.076  16.509 1.00 11.45 ?  86   ALA A CB   1 
ATOM   1068  H H    . ALA A 1 120 ? 6.633   12.275  14.890 1.00 11.27 ?  86   ALA A H    1 
ATOM   1069  H HA   . ALA A 1 120 ? 8.823   10.833  14.943 1.00 12.26 ?  86   ALA A HA   1 
ATOM   1070  H HB1  . ALA A 1 120 ? 9.159   11.738  17.051 1.00 13.75 ?  86   ALA A HB1  1 
ATOM   1071  H HB2  . ALA A 1 120 ? 8.709   12.878  16.041 1.00 13.75 ?  86   ALA A HB2  1 
ATOM   1072  H HB3  . ALA A 1 120 ? 7.663   12.270  17.070 1.00 13.75 ?  86   ALA A HB3  1 
ATOM   1073  N N    . ILE A 1 121 ? 6.408   9.554   16.596 1.00 10.51 ?  87   ILE A N    1 
ATOM   1074  C CA   . ILE A 1 121 ? 5.973   8.283   17.177 1.00 10.32 ?  87   ILE A CA   1 
ATOM   1075  C C    . ILE A 1 121 ? 6.094   7.171   16.149 1.00 9.73  ?  87   ILE A C    1 
ATOM   1076  O O    . ILE A 1 121 ? 6.622   6.085   16.433 1.00 10.54 ?  87   ILE A O    1 
ATOM   1077  C CB   . ILE A 1 121 ? 4.524   8.399   17.696 1.00 10.42 ?  87   ILE A CB   1 
ATOM   1078  C CG1  . ILE A 1 121 ? 4.467   9.335   18.909 1.00 10.17 ?  87   ILE A CG1  1 
ATOM   1079  C CG2  . ILE A 1 121 ? 3.956   7.024   18.027 1.00 10.21 ?  87   ILE A CG2  1 
ATOM   1080  C CD1  . ILE A 1 121 ? 3.035   9.694   19.315 1.00 11.15 ?  87   ILE A CD1  1 
ATOM   1081  H H    . ILE A 1 121 ? 5.808   10.170  16.583 1.00 12.61 ?  87   ILE A H    1 
ATOM   1082  H HA   . ILE A 1 121 ? 6.550   8.073   17.928 1.00 12.38 ?  87   ILE A HA   1 
ATOM   1083  H HB   . ILE A 1 121 ? 3.976   8.783   16.994 1.00 12.51 ?  87   ILE A HB   1 
ATOM   1084  H HG12 . ILE A 1 121 ? 4.892   8.899   19.664 1.00 12.20 ?  87   ILE A HG12 1 
ATOM   1085  H HG13 . ILE A 1 121 ? 4.934   10.158  18.696 1.00 12.20 ?  87   ILE A HG13 1 
ATOM   1086  H HG21 . ILE A 1 121 ? 3.066   7.131   18.397 1.00 12.25 ?  87   ILE A HG21 1 
ATOM   1087  H HG22 . ILE A 1 121 ? 3.916   6.495   17.215 1.00 12.25 ?  87   ILE A HG22 1 
ATOM   1088  H HG23 . ILE A 1 121 ? 4.534   6.591   18.675 1.00 12.25 ?  87   ILE A HG23 1 
ATOM   1089  H HD11 . ILE A 1 121 ? 3.063   10.275  20.091 1.00 13.38 ?  87   ILE A HD11 1 
ATOM   1090  H HD12 . ILE A 1 121 ? 2.603   10.150  18.576 1.00 13.38 ?  87   ILE A HD12 1 
ATOM   1091  H HD13 . ILE A 1 121 ? 2.553   8.880   19.528 1.00 13.38 ?  87   ILE A HD13 1 
ATOM   1092  N N    . LYS A 1 122 ? 5.576   7.418   14.941 1.00 10.04 ?  88   LYS A N    1 
ATOM   1093  C CA   . LYS A 1 122 ? 5.531   6.379   13.914 1.00 11.93 ?  88   LYS A CA   1 
ATOM   1094  C C    . LYS A 1 122 ? 6.918   5.960   13.453 1.00 13.20 ?  88   LYS A C    1 
ATOM   1095  O O    . LYS A 1 122 ? 7.112   4.798   13.075 1.00 13.78 ?  88   LYS A O    1 
ATOM   1096  C CB   . LYS A 1 122 ? 4.693   6.852   12.732 1.00 12.53 ?  88   LYS A CB   1 
ATOM   1097  C CG   . LYS A 1 122 ? 3.216   6.957   13.031 1.00 12.13 ?  88   LYS A CG   1 
ATOM   1098  C CD   . LYS A 1 122 ? 2.569   5.621   13.265 1.00 14.66 ?  88   LYS A CD   1 
ATOM   1099  C CE   . LYS A 1 122 ? 1.042   5.741   13.342 1.00 14.35 ?  88   LYS A CE   1 
ATOM   1100  N NZ   . LYS A 1 122 ? 0.379   4.443   13.120 1.00 17.24 ?  88   LYS A NZ   1 
ATOM   1101  H H    . LYS A 1 122 ? 5.247   8.173   14.694 1.00 12.04 ?  88   LYS A H    1 
ATOM   1102  H HA   . LYS A 1 122 ? 5.105   5.594   14.292 1.00 14.32 ?  88   LYS A HA   1 
ATOM   1103  H HB2  . LYS A 1 122 ? 5.002   7.731   12.463 1.00 15.04 ?  88   LYS A HB2  1 
ATOM   1104  H HB3  . LYS A 1 122 ? 4.802   6.224   12.002 1.00 15.04 ?  88   LYS A HB3  1 
ATOM   1105  H HG2  . LYS A 1 122 ? 3.092   7.492   13.830 1.00 14.56 ?  88   LYS A HG2  1 
ATOM   1106  H HG3  . LYS A 1 122 ? 2.770   7.377   12.279 1.00 14.56 ?  88   LYS A HG3  1 
ATOM   1107  H HD2  . LYS A 1 122 ? 2.792   5.024   12.533 1.00 17.60 ?  88   LYS A HD2  1 
ATOM   1108  H HD3  . LYS A 1 122 ? 2.889   5.252   14.103 1.00 17.60 ?  88   LYS A HD3  1 
ATOM   1109  H HE2  . LYS A 1 122 ? 0.790   6.063   14.221 1.00 17.22 ?  88   LYS A HE2  1 
ATOM   1110  H HE3  . LYS A 1 122 ? 0.735   6.359   12.661 1.00 17.22 ?  88   LYS A HE3  1 
ATOM   1111  H HZ1  . LYS A 1 122 ? 0.593   4.126   12.316 1.00 20.69 ?  88   LYS A HZ1  1 
ATOM   1112  H HZ2  . LYS A 1 122 ? 0.638   3.859   13.739 1.00 20.69 ?  88   LYS A HZ2  1 
ATOM   1113  H HZ3  . LYS A 1 122 ? -0.504  4.541   13.166 1.00 20.69 ?  88   LYS A HZ3  1 
ATOM   1114  N N    . LEU A 1 123 ? 7.888   6.864   13.484 1.00 12.77 ?  89   LEU A N    1 
ATOM   1115  C CA   . LEU A 1 123 ? 9.247   6.485   13.117 1.00 12.53 ?  89   LEU A CA   1 
ATOM   1116  C C    . LEU A 1 123 ? 9.845   5.534   14.140 1.00 16.41 ?  89   LEU A C    1 
ATOM   1117  O O    . LEU A 1 123 ? 10.700  4.711   13.786 1.00 17.67 ?  89   LEU A O    1 
ATOM   1118  C CB   . LEU A 1 123 ? 10.109  7.736   12.971 1.00 13.99 ?  89   LEU A CB   1 
ATOM   1119  C CG   . LEU A 1 123 ? 9.943   8.443   11.630 1.00 21.54 ?  89   LEU A CG   1 
ATOM   1120  C CD1  . LEU A 1 123 ? 10.644  9.793   11.644 1.00 22.64 ?  89   LEU A CD1  1 
ATOM   1121  C CD2  . LEU A 1 123 ? 10.468  7.606   10.457 1.00 27.67 ?  89   LEU A CD2  1 
ATOM   1122  H H    . LEU A 1 123 ? 7.789   7.689   13.708 1.00 15.33 ?  89   LEU A H    1 
ATOM   1123  H HA   . LEU A 1 123 ? 9.236   6.032   12.260 1.00 15.04 ?  89   LEU A HA   1 
ATOM   1124  H HB2  . LEU A 1 123 ? 9.868   8.364   13.670 1.00 16.79 ?  89   LEU A HB2  1 
ATOM   1125  H HB3  . LEU A 1 123 ? 11.041  7.483   13.059 1.00 16.79 ?  89   LEU A HB3  1 
ATOM   1126  H HG   . LEU A 1 123 ? 8.992   8.576   11.492 1.00 25.85 ?  89   LEU A HG   1 
ATOM   1127  H HD11 . LEU A 1 123 ? 10.526  10.220  10.781 1.00 27.17 ?  89   LEU A HD11 1 
ATOM   1128  H HD12 . LEU A 1 123 ? 10.256  10.343  12.342 1.00 27.17 ?  89   LEU A HD12 1 
ATOM   1129  H HD13 . LEU A 1 123 ? 11.589  9.656   11.818 1.00 27.17 ?  89   LEU A HD13 1 
ATOM   1130  H HD21 . LEU A 1 123 ? 10.382  8.120   9.638  1.00 33.21 ?  89   LEU A HD21 1 
ATOM   1131  H HD22 . LEU A 1 123 ? 11.401  7.391   10.615 1.00 33.21 ?  89   LEU A HD22 1 
ATOM   1132  H HD23 . LEU A 1 123 ? 9.947   6.791   10.392 1.00 33.21 ?  89   LEU A HD23 1 
ATOM   1133  N N    . LYS A 1 124 ? 9.422   5.621   15.404 1.00 13.21 ?  90   LYS A N    1 
ATOM   1134  C CA   . LYS A 1 124 ? 9.897   4.691   16.420 1.00 12.29 ?  90   LYS A CA   1 
ATOM   1135  C C    . LYS A 1 124 ? 9.110   3.388   16.407 1.00 15.22 ?  90   LYS A C    1 
ATOM   1136  O O    . LYS A 1 124 ? 9.692   2.315   16.593 1.00 16.76 ?  90   LYS A O    1 
ATOM   1137  C CB   . LYS A 1 124 ? 9.810   5.339   17.804 1.00 16.04 ?  90   LYS A CB   1 
ATOM   1138  C CG   . LYS A 1 124 ? 10.172  4.438   18.957 1.00 27.64 ?  90   LYS A CG   1 
ATOM   1139  C CD   . LYS A 1 124 ? 11.614  3.965   18.888 1.00 35.00 ?  90   LYS A CD   1 
ATOM   1140  C CE   . LYS A 1 124 ? 12.053  3.409   20.233 1.00 31.40 ?  90   LYS A CE   1 
ATOM   1141  N NZ   . LYS A 1 124 ? 12.751  2.100   20.087 1.00 48.55 ?  90   LYS A NZ   1 
ATOM   1142  H H    . LYS A 1 124 ? 8.863   6.207   15.694 1.00 15.85 ?  90   LYS A H    1 
ATOM   1143  H HA   . LYS A 1 124 ? 10.826  4.484   16.237 1.00 14.75 ?  90   LYS A HA   1 
ATOM   1144  H HB2  . LYS A 1 124 ? 10.415  6.097   17.826 1.00 19.25 ?  90   LYS A HB2  1 
ATOM   1145  H HB3  . LYS A 1 124 ? 8.898   5.639   17.945 1.00 19.25 ?  90   LYS A HB3  1 
ATOM   1146  H HG2  . LYS A 1 124 ? 10.053  4.922   19.789 1.00 33.17 ?  90   LYS A HG2  1 
ATOM   1147  H HG3  . LYS A 1 124 ? 9.598   3.656   18.943 1.00 33.17 ?  90   LYS A HG3  1 
ATOM   1148  H HD2  . LYS A 1 124 ? 11.696  3.265   18.221 1.00 42.00 ?  90   LYS A HD2  1 
ATOM   1149  H HD3  . LYS A 1 124 ? 12.191  4.711   18.658 1.00 42.00 ?  90   LYS A HD3  1 
ATOM   1150  H HE2  . LYS A 1 124 ? 12.663  4.034   20.654 1.00 37.69 ?  90   LYS A HE2  1 
ATOM   1151  H HE3  . LYS A 1 124 ? 11.273  3.276   20.794 1.00 37.69 ?  90   LYS A HE3  1 
ATOM   1152  H HZ1  . LYS A 1 124 ? 12.992  1.793   20.887 1.00 58.26 ?  90   LYS A HZ1  1 
ATOM   1153  H HZ2  . LYS A 1 124 ? 12.211  1.508   19.701 1.00 58.26 ?  90   LYS A HZ2  1 
ATOM   1154  H HZ3  . LYS A 1 124 ? 13.479  2.197   19.584 1.00 58.26 ?  90   LYS A HZ3  1 
ATOM   1155  N N    . ASN A 1 125 ? 7.788   3.446   16.225 1.00 13.81 ?  91   ASN A N    1 
ATOM   1156  C CA   . ASN A 1 125 ? 6.965   2.240   16.206 1.00 12.81 ?  91   ASN A CA   1 
ATOM   1157  C C    . ASN A 1 125 ? 5.777   2.482   15.283 1.00 14.85 ?  91   ASN A C    1 
ATOM   1158  O O    . ASN A 1 125 ? 4.788   3.093   15.700 1.00 13.14 ?  91   ASN A O    1 
ATOM   1159  C CB   . ASN A 1 125 ? 6.489   1.874   17.599 1.00 12.57 ?  91   ASN A CB   1 
ATOM   1160  C CG   . ASN A 1 125 ? 5.856   0.506   17.634 1.00 18.22 ?  91   ASN A CG   1 
ATOM   1161  O OD1  . ASN A 1 125 ? 5.428   -0.008  16.595 1.00 16.21 ?  91   ASN A OD1  1 
ATOM   1162  N ND2  . ASN A 1 125 ? 5.870   -0.129  18.799 1.00 22.65 ?  91   ASN A ND2  1 
ATOM   1163  H H    . ASN A 1 125 ? 7.345   4.174   16.111 1.00 16.57 ?  91   ASN A H    1 
ATOM   1164  H HA   . ASN A 1 125 ? 7.498   1.513   15.846 1.00 15.37 ?  91   ASN A HA   1 
ATOM   1165  H HB2  . ASN A 1 125 ? 7.246   1.874   18.206 1.00 15.08 ?  91   ASN A HB2  1 
ATOM   1166  H HB3  . ASN A 1 125 ? 5.829   2.522   17.892 1.00 15.08 ?  91   ASN A HB3  1 
ATOM   1167  H HD21 . ASN A 1 125 ? 5.520   -0.912  18.866 1.00 27.18 ?  91   ASN A HD21 1 
ATOM   1168  H HD22 . ASN A 1 125 ? 6.228   0.242   19.486 1.00 27.18 ?  91   ASN A HD22 1 
ATOM   1169  N N    . ASN A 1 126 ? 5.844   1.962   14.062 1.00 14.52 ?  92   ASN A N    1 
ATOM   1170  C CA   . ASN A 1 126 ? 4.785   2.244   13.102 1.00 15.57 ?  92   ASN A CA   1 
ATOM   1171  C C    . ASN A 1 126 ? 3.509   1.471   13.400 1.00 14.53 ?  92   ASN A C    1 
ATOM   1172  O O    . ASN A 1 126 ? 2.478   1.762   12.780 1.00 18.75 ?  92   ASN A O    1 
ATOM   1173  C CB   . ASN A 1 126 ? 5.245   1.984   11.661 1.00 19.04 ?  92   ASN A CB   1 
ATOM   1174  C CG   . ASN A 1 126 ? 5.879   0.635   11.482 1.00 32.56 ?  92   ASN A CG   1 
ATOM   1175  O OD1  . ASN A 1 126 ? 5.518   -0.329  12.158 1.00 31.29 ?  92   ASN A OD1  1 
ATOM   1176  N ND2  . ASN A 1 126 ? 6.840   0.549   10.561 1.00 41.68 ?  92   ASN A ND2  1 
ATOM   1177  H H    . ASN A 1 126 ? 6.475   1.455   13.774 1.00 17.42 ?  92   ASN A H    1 
ATOM   1178  H HA   . ASN A 1 126 ? 4.580   3.191   13.147 1.00 18.69 ?  92   ASN A HA   1 
ATOM   1179  H HB2  . ASN A 1 126 ? 4.477   2.034   11.071 1.00 22.85 ?  92   ASN A HB2  1 
ATOM   1180  H HB3  . ASN A 1 126 ? 5.899   2.656   11.413 1.00 22.85 ?  92   ASN A HB3  1 
ATOM   1181  H HD21 . ASN A 1 126 ? 7.065   1.245   10.109 1.00 50.02 ?  92   ASN A HD21 1 
ATOM   1182  H HD22 . ASN A 1 126 ? 7.235   -0.202  10.420 1.00 50.02 ?  92   ASN A HD22 1 
ATOM   1183  N N    . LYS A 1 127 ? 3.536   0.548   14.365 1.00 12.90 ?  93   LYS A N    1 
ATOM   1184  C CA   . LYS A 1 127 ? 2.345   -0.190  14.757 1.00 13.72 ?  93   LYS A CA   1 
ATOM   1185  C C    . LYS A 1 127 ? 1.519   0.531   15.815 1.00 11.67 ?  93   LYS A C    1 
ATOM   1186  O O    . LYS A 1 127 ? 0.355   0.174   16.009 1.00 11.82 ?  93   LYS A O    1 
ATOM   1187  C CB   . LYS A 1 127 ? 2.741   -1.581  15.269 1.00 15.08 ?  93   LYS A CB   1 
ATOM   1188  C CG   . LYS A 1 127 ? 3.368   -2.499  14.202 1.00 19.94 ?  93   LYS A CG   1 
ATOM   1189  C CD   . LYS A 1 127 ? 3.461   -3.932  14.722 1.00 35.21 ?  93   LYS A CD   1 
ATOM   1190  C CE   . LYS A 1 127 ? 4.215   -4.839  13.756 1.00 40.36 ?  93   LYS A CE   1 
ATOM   1191  N NZ   . LYS A 1 127 ? 4.358   -6.227  14.290 1.00 44.96 ?  93   LYS A NZ   1 
ATOM   1192  H H    . LYS A 1 127 ? 4.241   0.334   14.808 1.00 15.48 ?  93   LYS A H    1 
ATOM   1193  H HA   . LYS A 1 127 ? 1.778   -0.311  13.979 1.00 16.47 ?  93   LYS A HA   1 
ATOM   1194  H HB2  . LYS A 1 127 ? 3.391   -1.474  15.981 1.00 18.09 ?  93   LYS A HB2  1 
ATOM   1195  H HB3  . LYS A 1 127 ? 1.947   -2.024  15.606 1.00 18.09 ?  93   LYS A HB3  1 
ATOM   1196  H HG2  . LYS A 1 127 ? 2.817   -2.495  13.404 1.00 23.93 ?  93   LYS A HG2  1 
ATOM   1197  H HG3  . LYS A 1 127 ? 4.262   -2.188  13.990 1.00 23.93 ?  93   LYS A HG3  1 
ATOM   1198  H HD2  . LYS A 1 127 ? 3.932   -3.935  15.570 1.00 42.25 ?  93   LYS A HD2  1 
ATOM   1199  H HD3  . LYS A 1 127 ? 2.567   -4.289  14.837 1.00 42.25 ?  93   LYS A HD3  1 
ATOM   1200  H HE2  . LYS A 1 127 ? 3.730   -4.885  12.917 1.00 48.43 ?  93   LYS A HE2  1 
ATOM   1201  H HE3  . LYS A 1 127 ? 5.103   -4.478  13.607 1.00 48.43 ?  93   LYS A HE3  1 
ATOM   1202  H HZ1  . LYS A 1 127 ? 4.801   -6.733  13.706 1.00 53.95 ?  93   LYS A HZ1  1 
ATOM   1203  H HZ2  . LYS A 1 127 ? 4.807   -6.213  15.058 1.00 53.95 ?  93   LYS A HZ2  1 
ATOM   1204  H HZ3  . LYS A 1 127 ? 3.555   -6.584  14.430 1.00 53.95 ?  93   LYS A HZ3  1 
ATOM   1205  N N    . ALA A 1 128 ? 2.076   1.540   16.475 1.00 11.10 ?  94   ALA A N    1 
ATOM   1206  C CA   . ALA A 1 128 ? 1.315   2.319   17.450 1.00 11.16 ?  94   ALA A CA   1 
ATOM   1207  C C    . ALA A 1 128 ? 0.197   3.053   16.733 1.00 11.98 ?  94   ALA A C    1 
ATOM   1208  O O    . ALA A 1 128 ? 0.416   3.645   15.677 1.00 14.33 ?  94   ALA A O    1 
ATOM   1209  C CB   . ALA A 1 128 ? 2.230   3.354   18.100 1.00 12.99 ?  94   ALA A CB   1 
ATOM   1210  H H    . ALA A 1 128 ? 2.891   1.795   16.379 1.00 13.32 ?  94   ALA A H    1 
ATOM   1211  H HA   . ALA A 1 128 ? 0.950   1.736   18.133 1.00 13.40 ?  94   ALA A HA   1 
ATOM   1212  H HB1  . ALA A 1 128 ? 1.698   3.937   18.663 1.00 15.59 ?  94   ALA A HB1  1 
ATOM   1213  H HB2  . ALA A 1 128 ? 2.896   2.895   18.635 1.00 15.59 ?  94   ALA A HB2  1 
ATOM   1214  H HB3  . ALA A 1 128 ? 2.665   3.873   17.405 1.00 15.59 ?  94   ALA A HB3  1 
ATOM   1215  N N    . LYS A 1 129 ? -1.003  3.027   17.304 1.00 8.74  ?  95   LYS A N    1 
ATOM   1216  C CA   . LYS A 1 129 ? -2.129  3.760   16.732 1.00 9.18  ?  95   LYS A CA   1 
ATOM   1217  C C    . LYS A 1 129 ? -2.266  5.113   17.406 1.00 7.58  ?  95   LYS A C    1 
ATOM   1218  O O    . LYS A 1 129 ? -2.278  5.193   18.642 1.00 10.23 ?  95   LYS A O    1 
ATOM   1219  C CB   . LYS A 1 129 ? -3.433  2.989   16.896 1.00 9.57  ?  95   LYS A CB   1 
ATOM   1220  C CG   . LYS A 1 129 ? -3.466  1.668   16.139 1.00 10.24 ?  95   LYS A CG   1 
ATOM   1221  C CD   . LYS A 1 129 ? -3.418  1.849   14.624 1.00 10.63 ?  95   LYS A CD   1 
ATOM   1222  C CE   . LYS A 1 129 ? -3.594  0.529   13.917 1.00 10.58 ?  95   LYS A CE   1 
ATOM   1223  N NZ   . LYS A 1 129 ? -3.698  0.695   12.454 1.00 13.38 ?  95   LYS A NZ   1 
ATOM   1224  H H    . LYS A 1 129 ? -1.189  2.593   18.023 1.00 10.48 ?  95   LYS A H    1 
ATOM   1225  H HA   . LYS A 1 129 ? -1.958  3.894   15.786 1.00 11.01 ?  95   LYS A HA   1 
ATOM   1226  H HB2  . LYS A 1 129 ? -3.563  2.794   17.837 1.00 11.48 ?  95   LYS A HB2  1 
ATOM   1227  H HB3  . LYS A 1 129 ? -4.163  3.537   16.566 1.00 11.48 ?  95   LYS A HB3  1 
ATOM   1228  H HG2  . LYS A 1 129 ? -2.698  1.135   16.401 1.00 12.29 ?  95   LYS A HG2  1 
ATOM   1229  H HG3  . LYS A 1 129 ? -4.286  1.198   16.358 1.00 12.29 ?  95   LYS A HG3  1 
ATOM   1230  H HD2  . LYS A 1 129 ? -4.133  2.443   14.347 1.00 12.75 ?  95   LYS A HD2  1 
ATOM   1231  H HD3  . LYS A 1 129 ? -2.559  2.221   14.370 1.00 12.75 ?  95   LYS A HD3  1 
ATOM   1232  H HE2  . LYS A 1 129 ? -2.828  -0.037  14.103 1.00 12.70 ?  95   LYS A HE2  1 
ATOM   1233  H HE3  . LYS A 1 129 ? -4.406  0.104   14.232 1.00 12.70 ?  95   LYS A HE3  1 
ATOM   1234  H HZ1  . LYS A 1 129 ? -4.475  1.076   12.245 1.00 16.05 ?  95   LYS A HZ1  1 
ATOM   1235  H HZ2  . LYS A 1 129 ? -3.036  1.210   12.157 1.00 16.05 ?  95   LYS A HZ2  1 
ATOM   1236  H HZ3  . LYS A 1 129 ? -3.649  -0.098  12.053 1.00 16.05 ?  95   LYS A HZ3  1 
ATOM   1237  N N    . VAL A 1 130 ? -2.387  6.164   16.596 1.00 8.27  ?  96   VAL A N    1 
ATOM   1238  C CA   . VAL A 1 130 ? -2.419  7.549   17.063 1.00 8.05  ?  96   VAL A CA   1 
ATOM   1239  C C    . VAL A 1 130 ? -3.741  8.185   16.666 1.00 8.91  ?  96   VAL A C    1 
ATOM   1240  O O    . VAL A 1 130 ? -4.077  8.251   15.477 1.00 8.72  ?  96   VAL A O    1 
ATOM   1241  C CB   . VAL A 1 130 ? -1.238  8.361   16.515 1.00 7.30  ?  96   VAL A CB   1 
ATOM   1242  C CG1  . VAL A 1 130 ? -1.286  9.799   16.986 1.00 9.33  ?  96   VAL A CG1  1 
ATOM   1243  C CG2  . VAL A 1 130 ? 0.095   7.734   16.914 1.00 10.70 ?  96   VAL A CG2  1 
ATOM   1244  H H    . VAL A 1 130 ? -2.454  6.097   15.742 1.00 9.93  ?  96   VAL A H    1 
ATOM   1245  H HA   . VAL A 1 130 ? -2.379  7.546   18.032 1.00 9.66  ?  96   VAL A HA   1 
ATOM   1246  H HB   . VAL A 1 130 ? -1.307  8.353   15.547 1.00 8.76  ?  96   VAL A HB   1 
ATOM   1247  H HG11 . VAL A 1 130 ? -0.538  10.282  16.601 1.00 11.20 ?  96   VAL A HG11 1 
ATOM   1248  H HG12 . VAL A 1 130 ? -2.122  10.198  16.697 1.00 11.20 ?  96   VAL A HG12 1 
ATOM   1249  H HG13 . VAL A 1 130 ? -1.228  9.816   17.954 1.00 11.20 ?  96   VAL A HG13 1 
ATOM   1250  H HG21 . VAL A 1 130 ? 0.817   8.262   16.538 1.00 12.84 ?  96   VAL A HG21 1 
ATOM   1251  H HG22 . VAL A 1 130 ? 0.162   7.724   17.882 1.00 12.84 ?  96   VAL A HG22 1 
ATOM   1252  H HG23 . VAL A 1 130 ? 0.134   6.828   16.571 1.00 12.84 ?  96   VAL A HG23 1 
ATOM   1253  N N    . LEU A 1 131 ? -4.469  8.684   17.663 1.00 7.92  ?  97   LEU A N    1 
ATOM   1254  C CA   . LEU A 1 131 ? -5.736  9.367   17.453 1.00 7.30  ?  97   LEU A CA   1 
ATOM   1255  C C    . LEU A 1 131 ? -5.613  10.873  17.687 1.00 7.15  ?  97   LEU A C    1 
ATOM   1256  O O    . LEU A 1 131 ? -4.928  11.332  18.616 1.00 7.88  ?  97   LEU A O    1 
ATOM   1257  C CB   . LEU A 1 131 ? -6.815  8.820   18.390 1.00 8.97  ?  97   LEU A CB   1 
ATOM   1258  C CG   . LEU A 1 131 ? -6.989  7.308   18.435 1.00 7.67  ?  97   LEU A CG   1 
ATOM   1259  C CD1  . LEU A 1 131 ? -8.100  6.954   19.421 1.00 9.53  ?  97   LEU A CD1  1 
ATOM   1260  C CD2  . LEU A 1 131 ? -7.304  6.733   17.061 1.00 9.71  ?  97   LEU A CD2  1 
ATOM   1261  H H    . LEU A 1 131 ? -4.240  8.637   18.491 1.00 9.50  ?  97   LEU A H    1 
ATOM   1262  H HA   . LEU A 1 131 ? -5.997  9.227   16.529 1.00 8.76  ?  97   LEU A HA   1 
ATOM   1263  H HB2  . LEU A 1 131 ? -6.602  9.107   19.292 1.00 10.76 ?  97   LEU A HB2  1 
ATOM   1264  H HB3  . LEU A 1 131 ? -7.667  9.195   18.115 1.00 10.76 ?  97   LEU A HB3  1 
ATOM   1265  H HG   . LEU A 1 131 ? -6.155  6.907   18.726 1.00 9.20  ?  97   LEU A HG   1 
ATOM   1266  H HD11 . LEU A 1 131 ? -8.265  5.999   19.381 1.00 11.43 ?  97   LEU A HD11 1 
ATOM   1267  H HD12 . LEU A 1 131 ? -7.820  7.204   20.315 1.00 11.43 ?  97   LEU A HD12 1 
ATOM   1268  H HD13 . LEU A 1 131 ? -8.904  7.439   19.179 1.00 11.43 ?  97   LEU A HD13 1 
ATOM   1269  H HD21 . LEU A 1 131 ? -7.424  5.773   17.140 1.00 11.66 ?  97   LEU A HD21 1 
ATOM   1270  H HD22 . LEU A 1 131 ? -8.118  7.141   16.726 1.00 11.66 ?  97   LEU A HD22 1 
ATOM   1271  H HD23 . LEU A 1 131 ? -6.567  6.925   16.461 1.00 11.66 ?  97   LEU A HD23 1 
ATOM   1272  N N    . TYR A 1 132 ? -6.342  11.626  16.876 1.00 6.46  ?  98   TYR A N    1 
ATOM   1273  C CA   . TYR A 1 132 ? -6.431  13.073  16.980 1.00 7.88  ?  98   TYR A CA   1 
ATOM   1274  C C    . TYR A 1 132 ? -7.669  13.460  17.778 1.00 6.70  ?  98   TYR A C    1 
ATOM   1275  O O    . TYR A 1 132 ? -8.800  13.161  17.378 1.00 6.89  ?  98   TYR A O    1 
ATOM   1276  C CB   . TYR A 1 132 ? -6.574  13.640  15.579 1.00 7.72  ?  98   TYR A CB   1 
ATOM   1277  C CG   . TYR A 1 132 ? -6.610  15.144  15.469 1.00 7.63  ?  98   TYR A CG   1 
ATOM   1278  C CD1  . TYR A 1 132 ? -5.629  15.928  16.048 1.00 7.42  ?  98   TYR A CD1  1 
ATOM   1279  C CD2  . TYR A 1 132 ? -7.610  15.783  14.742 1.00 7.06  ?  98   TYR A CD2  1 
ATOM   1280  C CE1  . TYR A 1 132 ? -5.621  17.301  15.914 1.00 7.54  ?  98   TYR A CE1  1 
ATOM   1281  C CE2  . TYR A 1 132 ? -7.599  17.173  14.591 1.00 8.03  ?  98   TYR A CE2  1 
ATOM   1282  C CZ   . TYR A 1 132 ? -6.591  17.909  15.185 1.00 7.62  ?  98   TYR A CZ   1 
ATOM   1283  O OH   . TYR A 1 132 ? -6.533  19.282  15.061 1.00 8.30  ?  98   TYR A OH   1 
ATOM   1284  H H    . TYR A 1 132 ? -6.813  11.307  16.231 1.00 7.75  ?  98   TYR A H    1 
ATOM   1285  H HA   . TYR A 1 132 ? -5.648  13.419  17.434 1.00 9.45  ?  98   TYR A HA   1 
ATOM   1286  H HB2  . TYR A 1 132 ? -5.821  13.333  15.051 1.00 9.26  ?  98   TYR A HB2  1 
ATOM   1287  H HB3  . TYR A 1 132 ? -7.403  13.307  15.201 1.00 9.26  ?  98   TYR A HB3  1 
ATOM   1288  H HD1  . TYR A 1 132 ? -4.956  15.518  16.542 1.00 8.90  ?  98   TYR A HD1  1 
ATOM   1289  H HD2  . TYR A 1 132 ? -8.290  15.282  14.354 1.00 8.48  ?  98   TYR A HD2  1 
ATOM   1290  H HE1  . TYR A 1 132 ? -4.954  17.807  16.320 1.00 9.05  ?  98   TYR A HE1  1 
ATOM   1291  H HE2  . TYR A 1 132 ? -8.263  17.598  14.097 1.00 9.63  ?  98   TYR A HE2  1 
ATOM   1292  H HH   . TYR A 1 132 ? -7.020  19.534  14.424 1.00 9.96  ?  98   TYR A HH   1 
ATOM   1293  N N    . TYR A 1 133 ? -7.470  14.140  18.893 1.00 6.56  ?  99   TYR A N    1 
ATOM   1294  C CA   . TYR A 1 133 ? -8.605  14.645  19.672 1.00 6.25  ?  99   TYR A CA   1 
ATOM   1295  C C    . TYR A 1 133 ? -9.392  15.683  18.884 1.00 6.30  ?  99   TYR A C    1 
ATOM   1296  O O    . TYR A 1 133 ? -8.829  16.587  18.262 1.00 6.96  ?  99   TYR A O    1 
ATOM   1297  C CB   . TYR A 1 133 ? -8.065  15.267  20.953 1.00 7.65  ?  99   TYR A CB   1 
ATOM   1298  C CG   . TYR A 1 133 ? -9.094  15.960  21.852 1.00 6.65  ?  99   TYR A CG   1 
ATOM   1299  C CD1  . TYR A 1 133 ? -9.439  17.291  21.647 1.00 6.67  ?  99   TYR A CD1  1 
ATOM   1300  C CD2  . TYR A 1 133 ? -9.680  15.289  22.919 1.00 6.97  ?  99   TYR A CD2  1 
ATOM   1301  C CE1  . TYR A 1 133 ? -10.343 17.939  22.490 1.00 7.11  ?  99   TYR A CE1  1 
ATOM   1302  C CE2  . TYR A 1 133 ? -10.596 15.929  23.760 1.00 6.97  ?  99   TYR A CE2  1 
ATOM   1303  C CZ   . TYR A 1 133 ? -10.910 17.236  23.536 1.00 6.11  ?  99   TYR A CZ   1 
ATOM   1304  O OH   . TYR A 1 133 ? -11.810 17.914  24.338 1.00 7.78  ?  99   TYR A OH   1 
ATOM   1305  H H    . TYR A 1 133 ? -6.698  14.325  19.225 1.00 7.87  ?  99   TYR A H    1 
ATOM   1306  H HA   . TYR A 1 133 ? -9.212  13.920  19.886 1.00 7.51  ?  99   TYR A HA   1 
ATOM   1307  H HB2  . TYR A 1 133 ? -7.652  14.565  21.480 1.00 9.17  ?  99   TYR A HB2  1 
ATOM   1308  H HB3  . TYR A 1 133 ? -7.403  15.933  20.710 1.00 9.17  ?  99   TYR A HB3  1 
ATOM   1309  H HD1  . TYR A 1 133 ? -9.061  17.757  20.936 1.00 8.00  ?  99   TYR A HD1  1 
ATOM   1310  H HD2  . TYR A 1 133 ? -9.459  14.400  23.076 1.00 8.37  ?  99   TYR A HD2  1 
ATOM   1311  H HE1  . TYR A 1 133 ? -10.561 18.832  22.350 1.00 8.54  ?  99   TYR A HE1  1 
ATOM   1312  H HE2  . TYR A 1 133 ? -10.987 15.466  24.466 1.00 8.36  ?  99   TYR A HE2  1 
ATOM   1313  H HH   . TYR A 1 133 ? -11.940 17.485  25.049 1.00 9.33  ?  99   TYR A HH   1 
ATOM   1314  N N    . ARG A 1 134 ? -10.715 15.581  18.950 1.00 6.52  ?  100  ARG A N    1 
ATOM   1315  C CA   . ARG A 1 134 ? -11.546 16.654  18.425 1.00 7.16  ?  100  ARG A CA   1 
ATOM   1316  C C    . ARG A 1 134 ? -12.793 16.787  19.278 1.00 6.92  ?  100  ARG A C    1 
ATOM   1317  O O    . ARG A 1 134 ? -13.555 15.830  19.445 1.00 7.94  ?  100  ARG A O    1 
ATOM   1318  C CB   . ARG A 1 134 ? -11.951 16.429  16.965 1.00 7.78  ?  100  ARG A CB   1 
ATOM   1319  C CG   . ARG A 1 134 ? -12.359 17.727  16.287 1.00 7.89  ?  100  ARG A CG   1 
ATOM   1320  C CD   . ARG A 1 134 ? -11.154 18.543  15.838 1.00 7.84  ?  100  ARG A CD   1 
ATOM   1321  N NE   . ARG A 1 134 ? -11.527 19.649  14.962 1.00 7.85  ?  100  ARG A NE   1 
ATOM   1322  C CZ   . ARG A 1 134 ? -11.377 20.944  15.210 1.00 8.27  ?  100  ARG A CZ   1 
ATOM   1323  N NH1  . ARG A 1 134 ? -10.977 21.398  16.388 1.00 8.12  ?  100  ARG A NH1  1 
ATOM   1324  N NH2  . ARG A 1 134 ? -11.653 21.813  14.248 1.00 7.88  ?  100  ARG A NH2  1 
ATOM   1325  H H    . ARG A 1 134 ? -11.144 14.916  19.287 1.00 7.82  ?  100  ARG A H    1 
ATOM   1326  H HA   . ARG A 1 134 ? -11.029 17.473  18.478 1.00 8.59  ?  100  ARG A HA   1 
ATOM   1327  H HB2  . ARG A 1 134 ? -11.199 16.055  16.479 1.00 9.33  ?  100  ARG A HB2  1 
ATOM   1328  H HB3  . ARG A 1 134 ? -12.703 15.818  16.932 1.00 9.33  ?  100  ARG A HB3  1 
ATOM   1329  H HG2  . ARG A 1 134 ? -12.895 17.523  15.504 1.00 9.47  ?  100  ARG A HG2  1 
ATOM   1330  H HG3  . ARG A 1 134 ? -12.873 18.264  16.910 1.00 9.47  ?  100  ARG A HG3  1 
ATOM   1331  H HD2  . ARG A 1 134 ? -10.712 18.912  16.618 1.00 9.41  ?  100  ARG A HD2  1 
ATOM   1332  H HD3  . ARG A 1 134 ? -10.543 17.967  15.352 1.00 9.41  ?  100  ARG A HD3  1 
ATOM   1333  H HE   . ARG A 1 134 ? -11.880 19.440  14.207 1.00 9.42  ?  100  ARG A HE   1 
ATOM   1334  H HH11 . ARG A 1 134 ? -10.804 20.847  17.025 1.00 9.75  ?  100  ARG A HH11 1 
ATOM   1335  H HH12 . ARG A 1 134 ? -10.890 22.244  16.515 1.00 9.75  ?  100  ARG A HH12 1 
ATOM   1336  H HH21 . ARG A 1 134 ? -11.924 21.534  13.481 1.00 9.45  ?  100  ARG A HH21 1 
ATOM   1337  H HH22 . ARG A 1 134 ? -11.562 22.656  14.391 1.00 9.45  ?  100  ARG A HH22 1 
ATOM   1338  N N    . ASN A 1 135 ? -13.018 17.986  19.781 1.00 6.68  ?  101  ASN A N    1 
ATOM   1339  C CA   . ASN A 1 135 ? -14.224 18.280  20.535 1.00 6.77  ?  101  ASN A CA   1 
ATOM   1340  C C    . ASN A 1 135 ? -15.334 18.683  19.575 1.00 6.73  ?  101  ASN A C    1 
ATOM   1341  O O    . ASN A 1 135 ? -15.147 19.558  18.731 1.00 7.60  ?  101  ASN A O    1 
ATOM   1342  C CB   . ASN A 1 135 ? -13.927 19.390  21.529 1.00 6.33  ?  101  ASN A CB   1 
ATOM   1343  C CG   . ASN A 1 135 ? -14.911 19.431  22.658 1.00 6.07  ?  101  ASN A CG   1 
ATOM   1344  O OD1  . ASN A 1 135 ? -16.099 19.706  22.448 1.00 7.38  ?  101  ASN A OD1  1 
ATOM   1345  N ND2  . ASN A 1 135 ? -14.460 19.065  23.856 1.00 6.10  ?  101  ASN A ND2  1 
ATOM   1346  H H    . ASN A 1 135 ? -12.483 18.654  19.700 1.00 8.02  ?  101  ASN A H    1 
ATOM   1347  H HA   . ASN A 1 135 ? -14.529 17.500  21.024 1.00 8.12  ?  101  ASN A HA   1 
ATOM   1348  H HB2  . ASN A 1 135 ? -13.044 19.250  21.905 1.00 7.60  ?  101  ASN A HB2  1 
ATOM   1349  H HB3  . ASN A 1 135 ? -13.961 20.244  21.070 1.00 7.60  ?  101  ASN A HB3  1 
ATOM   1350  H HD21 . ASN A 1 135 ? -14.988 19.072  24.535 1.00 7.32  ?  101  ASN A HD21 1 
ATOM   1351  H HD22 . ASN A 1 135 ? -13.640 18.822  23.951 1.00 7.32  ?  101  ASN A HD22 1 
ATOM   1352  N N    . VAL A 1 136 ? -16.498 18.060  19.725 1.00 6.26  ?  102  VAL A N    1 
ATOM   1353  C CA   . VAL A 1 136 ? -17.586 18.264  18.779 1.00 7.48  ?  102  VAL A CA   1 
ATOM   1354  C C    . VAL A 1 136 ? -18.318 19.573  18.984 1.00 6.56  ?  102  VAL A C    1 
ATOM   1355  O O    . VAL A 1 136 ? -18.960 20.054  18.046 1.00 8.59  ?  102  VAL A O    1 
ATOM   1356  C CB   . VAL A 1 136 ? -18.536 17.051  18.761 1.00 7.46  ?  102  VAL A CB   1 
ATOM   1357  C CG1  . VAL A 1 136 ? -19.376 16.960  20.038 1.00 8.33  ?  102  VAL A CG1  1 
ATOM   1358  C CG2  . VAL A 1 136 ? -19.413 17.026  17.512 1.00 10.11 ?  102  VAL A CG2  1 
ATOM   1359  H H    . VAL A 1 136 ? -16.682 17.516  20.365 1.00 7.51  ?  102  VAL A H    1 
ATOM   1360  H HA   . VAL A 1 136 ? -17.203 18.325  17.890 1.00 8.98  ?  102  VAL A HA   1 
ATOM   1361  H HB   . VAL A 1 136 ? -17.979 16.258  18.731 1.00 8.95  ?  102  VAL A HB   1 
ATOM   1362  H HG11 . VAL A 1 136 ? -19.954 16.183  19.981 1.00 9.99  ?  102  VAL A HG11 1 
ATOM   1363  H HG12 . VAL A 1 136 ? -18.782 16.875  20.801 1.00 9.99  ?  102  VAL A HG12 1 
ATOM   1364  H HG13 . VAL A 1 136 ? -19.911 17.764  20.123 1.00 9.99  ?  102  VAL A HG13 1 
ATOM   1365  H HG21 . VAL A 1 136 ? -19.943 16.213  17.514 1.00 12.13 ?  102  VAL A HG21 1 
ATOM   1366  H HG22 . VAL A 1 136 ? -19.996 17.801  17.520 1.00 12.13 ?  102  VAL A HG22 1 
ATOM   1367  H HG23 . VAL A 1 136 ? -18.844 17.048  16.726 1.00 12.13 ?  102  VAL A HG23 1 
ATOM   1368  N N    . VAL A 1 137 ? -18.226 20.192  20.159 1.00 6.74  ?  103  VAL A N    1 
ATOM   1369  C CA   . VAL A 1 137 ? -18.958 21.435  20.410 1.00 6.71  ?  103  VAL A CA   1 
ATOM   1370  C C    . VAL A 1 137 ? -18.141 22.533  21.068 1.00 7.46  ?  103  VAL A C    1 
ATOM   1371  O O    . VAL A 1 137 ? -18.545 23.703  20.983 1.00 8.19  ?  103  VAL A O    1 
ATOM   1372  C CB   . VAL A 1 137 ? -20.265 21.225  21.206 1.00 7.34  ?  103  VAL A CB   1 
ATOM   1373  C CG1  . VAL A 1 137 ? -21.373 20.664  20.333 1.00 9.60  ?  103  VAL A CG1  1 
ATOM   1374  C CG2  . VAL A 1 137 ? -20.034 20.392  22.455 1.00 7.87  ?  103  VAL A CG2  1 
ATOM   1375  H H    . VAL A 1 137 ? -17.752 19.916  20.822 1.00 8.09  ?  103  VAL A H    1 
ATOM   1376  H HA   . VAL A 1 137 ? -19.217 21.753  19.531 1.00 8.05  ?  103  VAL A HA   1 
ATOM   1377  H HB   . VAL A 1 137 ? -20.570 22.094  21.508 1.00 8.81  ?  103  VAL A HB   1 
ATOM   1378  H HG11 . VAL A 1 137 ? -22.173 20.554  20.870 1.00 11.52 ?  103  VAL A HG11 1 
ATOM   1379  H HG12 . VAL A 1 137 ? -21.545 21.283  19.605 1.00 11.52 ?  103  VAL A HG12 1 
ATOM   1380  H HG13 . VAL A 1 137 ? -21.092 19.806  19.978 1.00 11.52 ?  103  VAL A HG13 1 
ATOM   1381  H HG21 . VAL A 1 137 ? -20.863 20.336  22.955 1.00 9.45  ?  103  VAL A HG21 1 
ATOM   1382  H HG22 . VAL A 1 137 ? -19.745 19.504  22.193 1.00 9.45  ?  103  VAL A HG22 1 
ATOM   1383  H HG23 . VAL A 1 137 ? -19.350 20.816  22.996 1.00 9.45  ?  103  VAL A HG23 1 
ATOM   1384  N N    . ILE A 1 138 ? -17.063 22.257  21.803 1.00 7.87  ?  104  ILE A N    1 
ATOM   1385  C CA   . ILE A 1 138 ? -16.358 23.300  22.553 1.00 7.08  ?  104  ILE A CA   1 
ATOM   1386  C C    . ILE A 1 138 ? -15.209 23.828  21.712 1.00 7.30  ?  104  ILE A C    1 
ATOM   1387  O O    . ILE A 1 138 ? -14.375 23.058  21.233 1.00 7.72  ?  104  ILE A O    1 
ATOM   1388  C CB   . ILE A 1 138 ? -15.842 22.765  23.903 1.00 7.01  ?  104  ILE A CB   1 
ATOM   1389  C CG1  . ILE A 1 138 ? -16.975 22.222  24.764 1.00 8.79  ?  104  ILE A CG1  1 
ATOM   1390  C CG2  . ILE A 1 138 ? -15.125 23.887  24.647 1.00 7.68  ?  104  ILE A CG2  1 
ATOM   1391  C CD1  . ILE A 1 138 ? -16.524 21.464  25.994 1.00 7.93  ?  104  ILE A CD1  1 
ATOM   1392  H H    . ILE A 1 138 ? -16.720 21.473  21.884 1.00 9.45  ?  104  ILE A H    1 
ATOM   1393  H HA   . ILE A 1 138 ? -16.975 24.029  22.726 1.00 8.50  ?  104  ILE A HA   1 
ATOM   1394  H HB   . ILE A 1 138 ? -15.231 22.035  23.721 1.00 8.41  ?  104  ILE A HB   1 
ATOM   1395  H HG12 . ILE A 1 138 ? -17.520 22.967  25.063 1.00 10.54 ?  104  ILE A HG12 1 
ATOM   1396  H HG13 . ILE A 1 138 ? -17.508 21.616  24.226 1.00 10.54 ?  104  ILE A HG13 1 
ATOM   1397  H HG21 . ILE A 1 138 ? -14.875 23.571  25.530 1.00 9.21  ?  104  ILE A HG21 1 
ATOM   1398  H HG22 . ILE A 1 138 ? -14.332 24.140  24.150 1.00 9.21  ?  104  ILE A HG22 1 
ATOM   1399  H HG23 . ILE A 1 138 ? -15.723 24.647  24.726 1.00 9.21  ?  104  ILE A HG23 1 
ATOM   1400  H HD11 . ILE A 1 138 ? -17.297 21.059  26.416 1.00 9.52  ?  104  ILE A HD11 1 
ATOM   1401  H HD12 . ILE A 1 138 ? -15.894 20.776  25.727 1.00 9.52  ?  104  ILE A HD12 1 
ATOM   1402  H HD13 . ILE A 1 138 ? -16.098 22.083  26.607 1.00 9.52  ?  104  ILE A HD13 1 
ATOM   1403  N N    . ASN A 1 139 ? -15.141 25.146  21.570 1.00 6.87  ?  105  ASN A N    1 
ATOM   1404  C CA   . ASN A 1 139 ? -14.126 25.855  20.769 1.00 7.42  ?  105  ASN A CA   1 
ATOM   1405  C C    . ASN A 1 139 ? -12.909 26.184  21.646 1.00 7.39  ?  105  ASN A C    1 
ATOM   1406  O O    . ASN A 1 139 ? -12.617 27.338  21.950 1.00 8.46  ?  105  ASN A O    1 
ATOM   1407  C CB   . ASN A 1 139 ? -14.787 27.100  20.166 1.00 7.37  ?  105  ASN A CB   1 
ATOM   1408  C CG   . ASN A 1 139 ? -13.854 28.046  19.427 1.00 8.83  ?  105  ASN A CG   1 
ATOM   1409  O OD1  . ASN A 1 139 ? -14.093 29.272  19.427 1.00 10.10 ?  105  ASN A OD1  1 
ATOM   1410  N ND2  . ASN A 1 139 ? -12.857 27.522  18.732 1.00 8.13  ?  105  ASN A ND2  1 
ATOM   1411  H H    . ASN A 1 139 ? -15.696 25.687  21.943 1.00 8.25  ?  105  ASN A H    1 
ATOM   1412  H HA   . ASN A 1 139 ? -13.798 25.292  20.050 1.00 8.90  ?  105  ASN A HA   1 
ATOM   1413  H HB2  . ASN A 1 139 ? -15.463 26.811  19.533 1.00 8.84  ?  105  ASN A HB2  1 
ATOM   1414  H HB3  . ASN A 1 139 ? -15.199 27.605  20.884 1.00 8.84  ?  105  ASN A HB3  1 
ATOM   1415  H HD21 . ASN A 1 139 ? -12.315 28.034  18.305 1.00 9.75  ?  105  ASN A HD21 1 
ATOM   1416  H HD22 . ASN A 1 139 ? -12.752 26.668  18.709 1.00 9.75  ?  105  ASN A HD22 1 
ATOM   1417  N N    . TRP A 1 140 ? -12.190 25.130  22.057 1.00 6.82  ?  106  TRP A N    1 
ATOM   1418  C CA   . TRP A 1 140 ? -10.954 25.277  22.814 1.00 7.26  ?  106  TRP A CA   1 
ATOM   1419  C C    . TRP A 1 140 ? -9.872  25.970  21.979 1.00 8.04  ?  106  TRP A C    1 
ATOM   1420  O O    . TRP A 1 140 ? -9.888  25.963  20.743 1.00 8.02  ?  106  TRP A O    1 
ATOM   1421  C CB   . TRP A 1 140 ? -10.443 23.905  23.271 1.00 7.42  ?  106  TRP A CB   1 
ATOM   1422  C CG   . TRP A 1 140 ? -11.273 23.240  24.349 1.00 7.72  ?  106  TRP A CG   1 
ATOM   1423  C CD1  . TRP A 1 140 ? -11.942 22.054  24.245 1.00 7.58  ?  106  TRP A CD1  1 
ATOM   1424  C CD2  . TRP A 1 140 ? -11.485 23.688  25.707 1.00 7.44  ?  106  TRP A CD2  1 
ATOM   1425  N NE1  . TRP A 1 140 ? -12.546 21.740  25.428 1.00 7.66  ?  106  TRP A NE1  1 
ATOM   1426  C CE2  . TRP A 1 140 ? -12.277 22.708  26.353 1.00 7.96  ?  106  TRP A CE2  1 
ATOM   1427  C CE3  . TRP A 1 140 ? -11.076 24.807  26.441 1.00 6.99  ?  106  TRP A CE3  1 
ATOM   1428  C CZ2  . TRP A 1 140 ? -12.691 22.831  27.675 1.00 7.63  ?  106  TRP A CZ2  1 
ATOM   1429  C CZ3  . TRP A 1 140 ? -11.476 24.923  27.756 1.00 9.38  ?  106  TRP A CZ3  1 
ATOM   1430  C CH2  . TRP A 1 140 ? -12.287 23.939  28.362 1.00 9.32  ?  106  TRP A CH2  1 
ATOM   1431  H H    . TRP A 1 140 ? -12.405 24.311  21.906 1.00 8.18  ?  106  TRP A H    1 
ATOM   1432  H HA   . TRP A 1 140 ? -11.130 25.824  23.595 1.00 8.71  ?  106  TRP A HA   1 
ATOM   1433  H HB2  . TRP A 1 140 ? -10.431 23.311  22.504 1.00 8.90  ?  106  TRP A HB2  1 
ATOM   1434  H HB3  . TRP A 1 140 ? -9.545  24.013  23.621 1.00 8.90  ?  106  TRP A HB3  1 
ATOM   1435  H HD1  . TRP A 1 140 ? -11.980 21.533  23.476 1.00 9.10  ?  106  TRP A HD1  1 
ATOM   1436  H HE1  . TRP A 1 140 ? -13.024 21.039  25.569 1.00 9.19  ?  106  TRP A HE1  1 
ATOM   1437  H HE3  . TRP A 1 140 ? -10.543 25.461  26.049 1.00 8.38  ?  106  TRP A HE3  1 
ATOM   1438  H HZ2  . TRP A 1 140 ? -13.223 22.182  28.076 1.00 9.15  ?  106  TRP A HZ2  1 
ATOM   1439  H HZ3  . TRP A 1 140 ? -11.207 25.663  28.251 1.00 11.26 ?  106  TRP A HZ3  1 
ATOM   1440  H HH2  . TRP A 1 140 ? -12.551 24.049  29.247 1.00 11.18 ?  106  TRP A HH2  1 
ATOM   1441  N N    . GLY A 1 141 ? -8.907  26.552  22.688 1.00 8.25  ?  107  GLY A N    1 
ATOM   1442  C CA   . GLY A 1 141 ? -7.852  27.325  22.067 1.00 8.56  ?  107  GLY A CA   1 
ATOM   1443  C C    . GLY A 1 141 ? -6.783  26.475  21.378 1.00 8.16  ?  107  GLY A C    1 
ATOM   1444  O O    . GLY A 1 141 ? -6.737  25.249  21.504 1.00 7.68  ?  107  GLY A O    1 
ATOM   1445  H H    . GLY A 1 141 ? -8.845  26.511  23.544 1.00 9.91  ?  107  GLY A H    1 
ATOM   1446  H HA2  . GLY A 1 141 ? -8.242  27.913  21.401 1.00 10.27 ?  107  GLY A HA2  1 
ATOM   1447  H HA3  . GLY A 1 141 ? -7.414  27.863  22.746 1.00 10.27 ?  107  GLY A HA3  1 
ATOM   1448  N N    . ASN A 1 142 ? -5.912  27.167  20.632 1.00 7.68  ?  108  ASN A N    1 
ATOM   1449  C CA   . ASN A 1 142 ? -4.631  26.706  20.070 1.00 7.87  ?  108  ASN A CA   1 
ATOM   1450  C C    . ASN A 1 142 ? -4.762  25.918  18.775 1.00 7.71  ?  108  ASN A C    1 
ATOM   1451  O O    . ASN A 1 142 ? -3.757  25.348  18.305 1.00 8.25  ?  108  ASN A O    1 
ATOM   1452  C CB   . ASN A 1 142 ? -3.749  25.994  21.104 1.00 8.35  ?  108  ASN A CB   1 
ATOM   1453  C CG   . ASN A 1 142 ? -3.250  26.939  22.153 1.00 9.25  ?  108  ASN A CG   1 
ATOM   1454  O OD1  . ASN A 1 142 ? -2.951  28.093  21.843 1.00 11.24 ?  108  ASN A OD1  1 
ATOM   1455  N ND2  . ASN A 1 142 ? -3.158  26.484  23.391 1.00 9.06  ?  108  ASN A ND2  1 
ATOM   1456  H H    . ASN A 1 142 ? -6.056  27.987  20.417 1.00 9.21  ?  108  ASN A H    1 
ATOM   1457  H HA   . ASN A 1 142 ? -4.133  27.493  19.798 1.00 9.45  ?  108  ASN A HA   1 
ATOM   1458  H HB2  . ASN A 1 142 ? -4.265  25.300  21.541 1.00 10.03 ?  108  ASN A HB2  1 
ATOM   1459  H HB3  . ASN A 1 142 ? -2.981  25.605  20.656 1.00 10.03 ?  108  ASN A HB3  1 
ATOM   1460  H HD21 . ASN A 1 142 ? -2.876  26.999  24.019 1.00 10.87 ?  108  ASN A HD21 1 
ATOM   1461  H HD22 . ASN A 1 142 ? -3.381  25.672  23.568 1.00 10.87 ?  108  ASN A HD22 1 
ATOM   1462  N N    . TYR A 1 143 ? -5.942  25.897  18.159 1.00 7.64  ?  109  TYR A N    1 
ATOM   1463  C CA   . TYR A 1 143 ? -6.098  25.417  16.785 1.00 7.64  ?  109  TYR A CA   1 
ATOM   1464  C C    . TYR A 1 143 ? -6.001  26.622  15.852 1.00 8.37  ?  109  TYR A C    1 
ATOM   1465  O O    . TYR A 1 143 ? -6.907  27.459  15.825 1.00 8.58  ?  109  TYR A O    1 
ATOM   1466  C CB   . TYR A 1 143 ? -7.443  24.714  16.579 1.00 8.08  ?  109  TYR A CB   1 
ATOM   1467  C CG   . TYR A 1 143 ? -7.638  23.448  17.398 1.00 7.71  ?  109  TYR A CG   1 
ATOM   1468  C CD1  . TYR A 1 143 ? -7.123  22.234  16.979 1.00 7.90  ?  109  TYR A CD1  1 
ATOM   1469  C CD2  . TYR A 1 143 ? -8.339  23.475  18.576 1.00 7.39  ?  109  TYR A CD2  1 
ATOM   1470  C CE1  . TYR A 1 143 ? -7.298  21.071  17.721 1.00 7.30  ?  109  TYR A CE1  1 
ATOM   1471  C CE2  . TYR A 1 143 ? -8.534  22.340  19.346 1.00 6.75  ?  109  TYR A CE2  1 
ATOM   1472  C CZ   . TYR A 1 143 ? -8.012  21.131  18.913 1.00 6.95  ?  109  TYR A CZ   1 
ATOM   1473  O OH   . TYR A 1 143 ? -8.202  20.015  19.691 1.00 6.93  ?  109  TYR A OH   1 
ATOM   1474  H H    . TYR A 1 143 ? -6.677  26.159  18.519 1.00 9.16  ?  109  TYR A H    1 
ATOM   1475  H HA   . TYR A 1 143 ? -5.388  24.784  16.595 1.00 9.17  ?  109  TYR A HA   1 
ATOM   1476  H HB2  . TYR A 1 143 ? -8.152  25.330  16.823 1.00 9.70  ?  109  TYR A HB2  1 
ATOM   1477  H HB3  . TYR A 1 143 ? -7.522  24.471  15.644 1.00 9.70  ?  109  TYR A HB3  1 
ATOM   1478  H HD1  . TYR A 1 143 ? -6.648  22.195  16.180 1.00 9.48  ?  109  TYR A HD1  1 
ATOM   1479  H HD2  . TYR A 1 143 ? -8.696  24.283  18.868 1.00 8.87  ?  109  TYR A HD2  1 
ATOM   1480  H HE1  . TYR A 1 143 ? -6.942  20.264  17.425 1.00 8.76  ?  109  TYR A HE1  1 
ATOM   1481  H HE2  . TYR A 1 143 ? -9.009  22.388  20.144 1.00 8.10  ?  109  TYR A HE2  1 
ATOM   1482  H HH   . TYR A 1 143 ? -7.996  19.325  19.259 1.00 8.31  ?  109  TYR A HH   1 
ATOM   1483  N N    . LYS A 1 144 ? -4.916  26.715  15.075 1.00 8.02  ?  110  LYS A N    1 
ATOM   1484  C CA   . LYS A 1 144 ? -4.764  27.874  14.202 1.00 9.14  ?  110  LYS A CA   1 
ATOM   1485  C C    . LYS A 1 144 ? -5.913  27.971  13.206 1.00 8.24  ?  110  LYS A C    1 
ATOM   1486  O O    . LYS A 1 144 ? -6.376  29.075  12.897 1.00 9.81  ?  110  LYS A O    1 
ATOM   1487  C CB   . LYS A 1 144 ? -3.414  27.835  13.488 1.00 11.04 ?  110  LYS A CB   1 
ATOM   1488  C CG   . LYS A 1 144 ? -3.213  26.683  12.533 1.00 13.60 ?  110  LYS A CG   1 
ATOM   1489  C CD   . LYS A 1 144 ? -1.860  26.826  11.813 1.00 16.40 ?  110  LYS A CD   1 
ATOM   1490  C CE   . LYS A 1 144 ? -1.623  25.673  10.903 1.00 20.44 ?  110  LYS A CE   1 
ATOM   1491  N NZ   . LYS A 1 144 ? -2.598  25.767  9.793  1.00 25.36 ?  110  LYS A NZ   1 
ATOM   1492  H H    . LYS A 1 144 ? -4.279  26.139  15.038 1.00 9.63  ?  110  LYS A H    1 
ATOM   1493  H HA   . LYS A 1 144 ? -4.777  28.676  14.747 1.00 10.96 ?  110  LYS A HA   1 
ATOM   1494  H HB2  . LYS A 1 144 ? -3.316  28.654  12.978 1.00 13.25 ?  110  LYS A HB2  1 
ATOM   1495  H HB3  . LYS A 1 144 ? -2.717  27.778  14.160 1.00 13.25 ?  110  LYS A HB3  1 
ATOM   1496  H HG2  . LYS A 1 144 ? -3.218  25.846  13.023 1.00 16.32 ?  110  LYS A HG2  1 
ATOM   1497  H HG3  . LYS A 1 144 ? -3.920  26.682  11.868 1.00 16.32 ?  110  LYS A HG3  1 
ATOM   1498  H HD2  . LYS A 1 144 ? -1.857  27.640  11.286 1.00 19.69 ?  110  LYS A HD2  1 
ATOM   1499  H HD3  . LYS A 1 144 ? -1.145  26.852  12.469 1.00 19.69 ?  110  LYS A HD3  1 
ATOM   1500  H HE2  . LYS A 1 144 ? -0.723  25.709  10.543 1.00 24.53 ?  110  LYS A HE2  1 
ATOM   1501  H HE3  . LYS A 1 144 ? -1.757  24.838  11.378 1.00 24.53 ?  110  LYS A HE3  1 
ATOM   1502  H HZ1  . LYS A 1 144 ? -2.421  25.148  9.179  1.00 30.43 ?  110  LYS A HZ1  1 
ATOM   1503  H HZ2  . LYS A 1 144 ? -3.423  25.639  10.102 1.00 30.43 ?  110  LYS A HZ2  1 
ATOM   1504  H HZ3  . LYS A 1 144 ? -2.553  26.571  9.415  1.00 30.43 ?  110  LYS A HZ3  1 
ATOM   1505  N N    . ASN A 1 145 ? -6.375  26.836  12.674 1.00 8.09  ?  111  ASN A N    1 
ATOM   1506  C CA   . ASN A 1 145 ? -7.421  26.903  11.660 1.00 8.52  ?  111  ASN A CA   1 
ATOM   1507  C C    . ASN A 1 145 ? -8.757  27.278  12.282 1.00 8.79  ?  111  ASN A C    1 
ATOM   1508  O O    . ASN A 1 145 ? -9.567  27.977  11.650 1.00 8.86  ?  111  ASN A O    1 
ATOM   1509  C CB   . ASN A 1 145 ? -7.516  25.598  10.880 1.00 9.70  ?  111  ASN A CB   1 
ATOM   1510  C CG   . ASN A 1 145 ? -6.270  25.314  10.091 1.00 10.88 ?  111  ASN A CG   1 
ATOM   1511  O OD1  . ASN A 1 145 ? -5.535  26.227  9.742  1.00 13.65 ?  111  ASN A OD1  1 
ATOM   1512  N ND2  . ASN A 1 145 ? -6.032  24.055  9.798  1.00 10.99 ?  111  ASN A ND2  1 
ATOM   1513  H H    . ASN A 1 145 ? -6.108  26.045  12.877 1.00 9.71  ?  111  ASN A H    1 
ATOM   1514  H HA   . ASN A 1 145 ? -7.187  27.586  11.012 1.00 10.23 ?  111  ASN A HA   1 
ATOM   1515  H HB2  . ASN A 1 145 ? -7.654  24.865  11.502 1.00 11.64 ?  111  ASN A HB2  1 
ATOM   1516  H HB3  . ASN A 1 145 ? -8.261  25.651  10.260 1.00 11.64 ?  111  ASN A HB3  1 
ATOM   1517  H HD21 . ASN A 1 145 ? -5.331  23.844  9.348  1.00 13.19 ?  111  ASN A HD21 1 
ATOM   1518  H HD22 . ASN A 1 145 ? -6.578  23.443  10.056 1.00 13.19 ?  111  ASN A HD22 1 
ATOM   1519  N N    . ASP A 1 146 ? -9.007  26.854  13.530 1.00 8.11  ?  112  ASP A N    1 
ATOM   1520  C CA   . ASP A 1 146 ? -10.243 27.255  14.184 1.00 7.69  ?  112  ASP A CA   1 
ATOM   1521  C C    . ASP A 1 146 ? -10.224 28.749  14.476 1.00 8.41  ?  112  ASP A C    1 
ATOM   1522  O O    . ASP A 1 146 ? -11.243 29.433  14.320 1.00 8.74  ?  112  ASP A O    1 
ATOM   1523  C CB   . ASP A 1 146 ? -10.458 26.490  15.503 1.00 7.48  ?  112  ASP A CB   1 
ATOM   1524  C CG   . ASP A 1 146 ? -10.651 24.992  15.332 1.00 7.72  ?  112  ASP A CG   1 
ATOM   1525  O OD1  . ASP A 1 146 ? -10.540 24.459  14.201 1.00 7.84  ?  112  ASP A OD1  1 
ATOM   1526  O OD2  . ASP A 1 146 ? -10.874 24.325  16.368 1.00 8.27  ?  112  ASP A OD2  1 
ATOM   1527  H H    . ASP A 1 146 ? -8.490  26.350  13.997 1.00 9.74  ?  112  ASP A H    1 
ATOM   1528  H HA   . ASP A 1 146 ? -10.979 27.037  13.591 1.00 9.23  ?  112  ASP A HA   1 
ATOM   1529  H HB2  . ASP A 1 146 ? -9.681  26.623  16.069 1.00 8.97  ?  112  ASP A HB2  1 
ATOM   1530  H HB3  . ASP A 1 146 ? -11.250 26.840  15.940 1.00 8.97  ?  112  ASP A HB3  1 
ATOM   1531  N N    . ASP A 1 147 ? -9.094  29.267  14.952 1.00 8.90  ?  113  ASP A N    1 
ATOM   1532  C CA   . ASP A 1 147 ? -9.007  30.703  15.234 1.00 8.35  ?  113  ASP A CA   1 
ATOM   1533  C C    . ASP A 1 147 ? -9.320  31.516  13.988 1.00 9.54  ?  113  ASP A C    1 
ATOM   1534  O O    . ASP A 1 147 ? -10.054 32.505  14.054 1.00 9.16  ?  113  ASP A O    1 
ATOM   1535  C CB   . ASP A 1 147 ? -7.608  31.061  15.745 1.00 10.25 ?  113  ASP A CB   1 
ATOM   1536  C CG   . ASP A 1 147 ? -7.307  30.481  17.128 1.00 11.02 ?  113  ASP A CG   1 
ATOM   1537  O OD1  . ASP A 1 147 ? -8.190  29.901  17.786 1.00 10.69 ?  113  ASP A OD1  1 
ATOM   1538  O OD2  . ASP A 1 147 ? -6.131  30.647  17.530 1.00 14.11 ?  113  ASP A OD2  1 
ATOM   1539  H H    . ASP A 1 147 ? -8.378  28.822  15.118 1.00 10.68 ?  113  ASP A H    1 
ATOM   1540  H HA   . ASP A 1 147 ? -9.651  30.923  15.926 1.00 10.02 ?  113  ASP A HA   1 
ATOM   1541  H HB2  . ASP A 1 147 ? -6.948  30.712  15.126 1.00 12.30 ?  113  ASP A HB2  1 
ATOM   1542  H HB3  . ASP A 1 147 ? -7.531  32.026  15.803 1.00 12.30 ?  113  ASP A HB3  1 
ATOM   1543  N N    . GLU A 1 148 ? -8.784  31.106  12.846 1.00 9.76  ?  114  GLU A N    1 
ATOM   1544  C CA   . GLU A 1 148 ? -9.051  31.827  11.605 1.00 9.99  ?  114  GLU A CA   1 
ATOM   1545  C C    . GLU A 1 148 ? -10.517 31.702  11.208 1.00 10.93 ?  114  GLU A C    1 
ATOM   1546  O O    . GLU A 1 148 ? -11.140 32.695  10.820 1.00 11.22 ?  114  GLU A O    1 
ATOM   1547  C CB   . GLU A 1 148 ? -8.136  31.304  10.515 1.00 12.88 ?  114  GLU A CB   1 
ATOM   1548  C CG   . GLU A 1 148 ? -8.426  31.836  9.134  1.00 16.22 ?  114  GLU A CG   1 
ATOM   1549  C CD   . GLU A 1 148 ? -7.344  31.485  8.131  1.00 37.58 ?  114  GLU A CD   1 
ATOM   1550  O OE1  . GLU A 1 148 ? -6.370  30.792  8.506  1.00 40.51 ?  114  GLU A OE1  1 
ATOM   1551  O OE2  . GLU A 1 148 ? -7.471  31.906  6.962  1.00 46.09 ?  114  GLU A OE2  1 
ATOM   1552  H H    . GLU A 1 148 ? -8.268  30.424  12.761 1.00 11.71 ?  114  GLU A H    1 
ATOM   1553  H HA   . GLU A 1 148 ? -8.862  32.771  11.724 1.00 11.99 ?  114  GLU A HA   1 
ATOM   1554  H HB2  . GLU A 1 148 ? -7.223  31.549  10.736 1.00 15.46 ?  114  GLU A HB2  1 
ATOM   1555  H HB3  . GLU A 1 148 ? -8.221  30.338  10.480 1.00 15.46 ?  114  GLU A HB3  1 
ATOM   1556  H HG2  . GLU A 1 148 ? -9.262  31.458  8.818  1.00 19.46 ?  114  GLU A HG2  1 
ATOM   1557  H HG3  . GLU A 1 148 ? -8.495  32.803  9.175  1.00 19.46 ?  114  GLU A HG3  1 
ATOM   1558  N N    . PHE A 1 149 ? -11.082 30.501  11.302 1.00 9.97  ?  115  PHE A N    1 
ATOM   1559  C CA   . PHE A 1 149 ? -12.476 30.265  10.940 1.00 8.91  ?  115  PHE A CA   1 
ATOM   1560  C C    . PHE A 1 149 ? -13.421 31.115  11.772 1.00 10.11 ?  115  PHE A C    1 
ATOM   1561  O O    . PHE A 1 149 ? -14.334 31.759  11.230 1.00 10.01 ?  115  PHE A O    1 
ATOM   1562  C CB   . PHE A 1 149 ? -12.762 28.777  11.122 1.00 9.31  ?  115  PHE A CB   1 
ATOM   1563  C CG   . PHE A 1 149 ? -14.189 28.378  10.917 1.00 9.08  ?  115  PHE A CG   1 
ATOM   1564  C CD1  . PHE A 1 149 ? -14.761 28.415  9.651  1.00 9.67  ?  115  PHE A CD1  1 
ATOM   1565  C CD2  . PHE A 1 149 ? -14.957 27.936  11.976 1.00 10.26 ?  115  PHE A CD2  1 
ATOM   1566  C CE1  . PHE A 1 149 ? -16.080 28.018  9.467  1.00 10.20 ?  115  PHE A CE1  1 
ATOM   1567  C CE2  . PHE A 1 149 ? -16.266 27.535  11.788 1.00 9.71  ?  115  PHE A CE2  1 
ATOM   1568  C CZ   . PHE A 1 149 ? -16.821 27.579  10.529 1.00 10.95 ?  115  PHE A CZ   1 
ATOM   1569  H H    . PHE A 1 149 ? -10.674 29.795  11.577 1.00 11.97 ?  115  PHE A H    1 
ATOM   1570  H HA   . PHE A 1 149 ? -12.626 30.510  10.014 1.00 10.69 ?  115  PHE A HA   1 
ATOM   1571  H HB2  . PHE A 1 149 ? -12.227 28.281  10.482 1.00 11.18 ?  115  PHE A HB2  1 
ATOM   1572  H HB3  . PHE A 1 149 ? -12.517 28.525  12.026 1.00 11.18 ?  115  PHE A HB3  1 
ATOM   1573  H HD1  . PHE A 1 149 ? -14.260 28.708  8.924  1.00 11.60 ?  115  PHE A HD1  1 
ATOM   1574  H HD2  . PHE A 1 149 ? -14.588 27.908  12.829 1.00 12.31 ?  115  PHE A HD2  1 
ATOM   1575  H HE1  . PHE A 1 149 ? -16.460 28.050  8.619  1.00 12.23 ?  115  PHE A HE1  1 
ATOM   1576  H HE2  . PHE A 1 149 ? -16.771 27.237  12.510 1.00 11.66 ?  115  PHE A HE2  1 
ATOM   1577  H HZ   . PHE A 1 149 ? -17.702 27.310  10.400 1.00 13.14 ?  115  PHE A HZ   1 
ATOM   1578  N N    . ILE A 1 150 ? -13.209 31.159  13.085 1.00 10.15 ?  116  ILE A N    1 
ATOM   1579  C CA   . ILE A 1 150 ? -14.072 31.922  13.973 1.00 10.91 ?  116  ILE A CA   1 
ATOM   1580  C C    . ILE A 1 150 ? -13.870 33.420  13.770 1.00 10.88 ?  116  ILE A C    1 
ATOM   1581  O O    . ILE A 1 150 ? -14.838 34.197  13.816 1.00 11.17 ?  116  ILE A O    1 
ATOM   1582  C CB   . ILE A 1 150 ? -13.835 31.490  15.435 1.00 10.22 ?  116  ILE A CB   1 
ATOM   1583  C CG1  . ILE A 1 150 ? -14.208 30.022  15.653 1.00 10.25 ?  116  ILE A CG1  1 
ATOM   1584  C CG2  . ILE A 1 150 ? -14.583 32.425  16.389 1.00 11.21 ?  116  ILE A CG2  1 
ATOM   1585  C CD1  . ILE A 1 150 ? -15.619 29.661  15.239 1.00 11.36 ?  116  ILE A CD1  1 
ATOM   1586  H H    . ILE A 1 150 ? -12.567 30.753  13.488 1.00 12.19 ?  116  ILE A H    1 
ATOM   1587  H HA   . ILE A 1 150 ? -14.996 31.728  13.753 1.00 13.09 ?  116  ILE A HA   1 
ATOM   1588  H HB   . ILE A 1 150 ? -12.887 31.564  15.626 1.00 12.26 ?  116  ILE A HB   1 
ATOM   1589  H HG12 . ILE A 1 150 ? -13.601 29.470  15.136 1.00 12.30 ?  116  ILE A HG12 1 
ATOM   1590  H HG13 . ILE A 1 150 ? -14.119 29.819  16.597 1.00 12.30 ?  116  ILE A HG13 1 
ATOM   1591  H HG21 . ILE A 1 150 ? -14.603 32.025  17.273 1.00 13.45 ?  116  ILE A HG21 1 
ATOM   1592  H HG22 . ILE A 1 150 ? -14.122 33.278  16.423 1.00 13.45 ?  116  ILE A HG22 1 
ATOM   1593  H HG23 . ILE A 1 150 ? -15.488 32.552  16.063 1.00 13.45 ?  116  ILE A HG23 1 
ATOM   1594  H HD11 . ILE A 1 150 ? -15.817 28.762  15.544 1.00 13.63 ?  116  ILE A HD11 1 
ATOM   1595  H HD12 . ILE A 1 150 ? -16.238 30.291  15.641 1.00 13.63 ?  116  ILE A HD12 1 
ATOM   1596  H HD13 . ILE A 1 150 ? -15.686 29.705  14.272 1.00 13.63 ?  116  ILE A HD13 1 
ATOM   1597  N N    A SER A 1 151 ? -12.622 33.855  13.549 0.62 10.27 ?  117  SER A N    1 
ATOM   1598  N N    B SER A 1 151 ? -12.621 33.851  13.556 0.38 10.37 ?  117  SER A N    1 
ATOM   1599  C CA   A SER A 1 151 ? -12.367 35.269  13.291 0.62 12.97 ?  117  SER A CA   1 
ATOM   1600  C CA   B SER A 1 151 ? -12.354 35.261  13.292 0.38 12.96 ?  117  SER A CA   1 
ATOM   1601  C C    A SER A 1 151 ? -13.125 35.730  12.058 0.62 12.76 ?  117  SER A C    1 
ATOM   1602  C C    B SER A 1 151 ? -13.103 35.732  12.057 0.38 12.80 ?  117  SER A C    1 
ATOM   1603  O O    A SER A 1 151 ? -13.744 36.806  12.057 0.62 14.84 ?  117  SER A O    1 
ATOM   1604  O O    B SER A 1 151 ? -13.704 36.817  12.058 0.38 14.89 ?  117  SER A O    1 
ATOM   1605  C CB   A SER A 1 151 ? -10.874 35.511  13.085 0.62 12.52 ?  117  SER A CB   1 
ATOM   1606  C CB   B SER A 1 151 ? -10.853 35.472  13.100 0.38 12.54 ?  117  SER A CB   1 
ATOM   1607  O OG   A SER A 1 151 ? -10.629 36.890  12.819 0.62 14.58 ?  117  SER A OG   1 
ATOM   1608  O OG   B SER A 1 151 ? -10.182 35.529  14.347 0.38 19.24 ?  117  SER A OG   1 
ATOM   1609  H H    A SER A 1 151 ? -11.921 33.357  13.543 0.62 12.33 ?  117  SER A H    1 
ATOM   1610  H H    B SER A 1 151 ? -11.921 33.351  13.560 0.38 12.45 ?  117  SER A H    1 
ATOM   1611  H HA   A SER A 1 151 ? -12.660 35.780  14.062 0.62 15.56 ?  117  SER A HA   1 
ATOM   1612  H HA   B SER A 1 151 ? -12.647 35.787  14.052 0.38 15.55 ?  117  SER A HA   1 
ATOM   1613  H HB2  A SER A 1 151 ? -10.396 35.252  13.888 0.62 15.03 ?  117  SER A HB2  1 
ATOM   1614  H HB2  B SER A 1 151 ? -10.495 34.733  12.583 0.38 15.04 ?  117  SER A HB2  1 
ATOM   1615  H HB3  A SER A 1 151 ? -10.567 34.982  12.332 0.62 15.03 ?  117  SER A HB3  1 
ATOM   1616  H HB3  B SER A 1 151 ? -10.710 36.307  12.627 0.38 15.04 ?  117  SER A HB3  1 
ATOM   1617  H HG   A SER A 1 151 ? -9.816  37.009  12.645 0.62 17.49 ?  117  SER A HG   1 
ATOM   1618  H HG   B SER A 1 151 ? -10.407 34.875  14.824 0.38 23.08 ?  117  SER A HG   1 
ATOM   1619  N N    . LYS A 1 152 ? -13.067 34.937  10.990 1.00 12.17 ?  118  LYS A N    1 
ATOM   1620  C CA   . LYS A 1 152 ? -13.710 35.306  9.734  1.00 11.89 ?  118  LYS A CA   1 
ATOM   1621  C C    . LYS A 1 152 ? -15.212 35.086  9.753  1.00 13.74 ?  118  LYS A C    1 
ATOM   1622  O O    . LYS A 1 152 ? -15.920 35.745  8.975  1.00 15.58 ?  118  LYS A O    1 
ATOM   1623  C CB   . LYS A 1 152 ? -13.036 34.566  8.582  1.00 13.86 ?  118  LYS A CB   1 
ATOM   1624  C CG   . LYS A 1 152 ? -11.580 35.001  8.412  1.00 21.05 ?  118  LYS A CG   1 
ATOM   1625  C CD   . LYS A 1 152 ? -10.792 34.226  7.385  1.00 33.36 ?  118  LYS A CD   1 
ATOM   1626  C CE   . LYS A 1 152 ? -9.529  35.022  7.015  1.00 47.77 ?  118  LYS A CE   1 
ATOM   1627  N NZ   . LYS A 1 152 ? -8.255  34.287  7.239  1.00 39.48 ?  118  LYS A NZ   1 
ATOM   1628  H H    . LYS A 1 152 ? -12.659 34.180  10.969 1.00 14.61 ?  118  LYS A H    1 
ATOM   1629  H HA   . LYS A 1 152 ? -13.586 36.253  9.566  1.00 14.26 ?  118  LYS A HA   1 
ATOM   1630  H HB2  . LYS A 1 152 ? -13.051 33.612  8.761  1.00 16.63 ?  118  LYS A HB2  1 
ATOM   1631  H HB3  . LYS A 1 152 ? -13.511 34.756  7.758  1.00 16.63 ?  118  LYS A HB3  1 
ATOM   1632  H HG2  . LYS A 1 152 ? -11.568 35.933  8.142  1.00 25.26 ?  118  LYS A HG2  1 
ATOM   1633  H HG3  . LYS A 1 152 ? -11.127 34.896  9.263  1.00 25.26 ?  118  LYS A HG3  1 
ATOM   1634  H HD2  . LYS A 1 152 ? -10.527 33.367  7.750  1.00 40.03 ?  118  LYS A HD2  1 
ATOM   1635  H HD3  . LYS A 1 152 ? -11.328 34.095  6.586  1.00 40.03 ?  118  LYS A HD3  1 
ATOM   1636  H HE2  . LYS A 1 152 ? -9.573  35.254  6.074  1.00 57.32 ?  118  LYS A HE2  1 
ATOM   1637  H HE3  . LYS A 1 152 ? -9.502  35.828  7.554  1.00 57.32 ?  118  LYS A HE3  1 
ATOM   1638  H HZ1  . LYS A 1 152 ? -7.577  34.734  6.874  1.00 47.38 ?  118  LYS A HZ1  1 
ATOM   1639  H HZ2  . LYS A 1 152 ? -8.105  34.196  8.111  1.00 47.38 ?  118  LYS A HZ2  1 
ATOM   1640  H HZ3  . LYS A 1 152 ? -8.300  33.479  6.868  1.00 47.38 ?  118  LYS A HZ3  1 
ATOM   1641  N N    . ASN A 1 153 ? -15.722 34.226  10.636 1.00 12.17 ?  119  ASN A N    1 
ATOM   1642  C CA   . ASN A 1 153 ? -17.124 33.801  10.617 1.00 11.42 ?  119  ASN A CA   1 
ATOM   1643  C C    . ASN A 1 153 ? -17.666 33.791  12.037 1.00 9.82  ?  119  ASN A C    1 
ATOM   1644  O O    . ASN A 1 153 ? -17.918 32.728  12.624 1.00 11.22 ?  119  ASN A O    1 
ATOM   1645  C CB   . ASN A 1 153 ? -17.241 32.419  9.982  1.00 11.21 ?  119  ASN A CB   1 
ATOM   1646  C CG   . ASN A 1 153 ? -16.615 32.348  8.613  1.00 12.15 ?  119  ASN A CG   1 
ATOM   1647  O OD1  . ASN A 1 153 ? -17.185 32.860  7.639  1.00 16.61 ?  119  ASN A OD1  1 
ATOM   1648  N ND2  . ASN A 1 153 ? -15.434 31.764  8.510  1.00 14.16 ?  119  ASN A ND2  1 
ATOM   1649  H H    . ASN A 1 153 ? -15.265 33.867  11.271 1.00 14.60 ?  119  ASN A H    1 
ATOM   1650  H HA   . ASN A 1 153 ? -17.646 34.437  10.103 1.00 13.71 ?  119  ASN A HA   1 
ATOM   1651  H HB2  . ASN A 1 153 ? -16.793 31.772  10.550 1.00 13.45 ?  119  ASN A HB2  1 
ATOM   1652  H HB3  . ASN A 1 153 ? -18.179 32.190  9.894  1.00 13.45 ?  119  ASN A HB3  1 
ATOM   1653  H HD21 . ASN A 1 153 ? -15.048 31.707  7.744  1.00 16.99 ?  119  ASN A HD21 1 
ATOM   1654  H HD22 . ASN A 1 153 ? -15.051 31.442  9.210  1.00 16.99 ?  119  ASN A HD22 1 
ATOM   1655  N N    . PRO A 1 154 ? -17.890 34.968  12.616 1.00 10.03 ?  120  PRO A N    1 
ATOM   1656  C CA   . PRO A 1 154 ? -18.417 35.013  13.995 1.00 11.98 ?  120  PRO A CA   1 
ATOM   1657  C C    . PRO A 1 154 ? -19.775 34.341  14.170 1.00 12.20 ?  120  PRO A C    1 
ATOM   1658  O O    . PRO A 1 154 ? -20.131 33.958  15.299 1.00 11.50 ?  120  PRO A O    1 
ATOM   1659  C CB   . PRO A 1 154 ? -18.472 36.515  14.322 1.00 13.83 ?  120  PRO A CB   1 
ATOM   1660  C CG   . PRO A 1 154 ? -18.457 37.187  12.968 1.00 16.91 ?  120  PRO A CG   1 
ATOM   1661  C CD   . PRO A 1 154 ? -17.630 36.310  12.068 1.00 12.72 ?  120  PRO A CD   1 
ATOM   1662  H HA   . PRO A 1 154 ? -17.782 34.591  14.594 1.00 14.37 ?  120  PRO A HA   1 
ATOM   1663  H HB2  . PRO A 1 154 ? -19.286 36.722  14.807 1.00 16.60 ?  120  PRO A HB2  1 
ATOM   1664  H HB3  . PRO A 1 154 ? -17.698 36.771  14.848 1.00 16.60 ?  120  PRO A HB3  1 
ATOM   1665  H HG2  . PRO A 1 154 ? -19.364 37.262  12.632 1.00 20.29 ?  120  PRO A HG2  1 
ATOM   1666  H HG3  . PRO A 1 154 ? -18.059 38.068  13.047 1.00 20.29 ?  120  PRO A HG3  1 
ATOM   1667  H HD2  . PRO A 1 154 ? -17.927 36.375  11.147 1.00 15.27 ?  120  PRO A HD2  1 
ATOM   1668  H HD3  . PRO A 1 154 ? -16.689 36.535  12.130 1.00 15.27 ?  120  PRO A HD3  1 
ATOM   1669  N N    . SER A 1 155 ? -20.547 34.183  13.094 1.00 11.06 ?  121  SER A N    1 
ATOM   1670  C CA   . SER A 1 155 ? -21.821 33.481  13.182 1.00 10.45 ?  121  SER A CA   1 
ATOM   1671  C C    . SER A 1 155 ? -21.652 31.988  13.445 1.00 9.96  ?  121  SER A C    1 
ATOM   1672  O O    . SER A 1 155 ? -22.643 31.289  13.665 1.00 10.80 ?  121  SER A O    1 
ATOM   1673  C CB   . SER A 1 155 ? -22.620 33.688  11.884 1.00 12.47 ?  121  SER A CB   1 
ATOM   1674  O OG   . SER A 1 155 ? -22.016 33.067  10.766 1.00 12.35 ?  121  SER A OG   1 
ATOM   1675  H H    . SER A 1 155 ? -20.354 34.473  12.308 1.00 13.27 ?  121  SER A H    1 
ATOM   1676  H HA   . SER A 1 155 ? -22.334 33.855  13.915 1.00 12.54 ?  121  SER A HA   1 
ATOM   1677  H HB2  . SER A 1 155 ? -23.506 33.312  12.004 1.00 14.97 ?  121  SER A HB2  1 
ATOM   1678  H HB3  . SER A 1 155 ? -22.684 34.640  11.711 1.00 14.97 ?  121  SER A HB3  1 
ATOM   1679  H HG   . SER A 1 155 ? -21.369 33.529  10.496 1.00 14.82 ?  121  SER A HG   1 
ATOM   1680  N N    . ALA A 1 156 ? -20.423 31.476  13.439 1.00 8.82  ?  122  ALA A N    1 
ATOM   1681  C CA   . ALA A 1 156 ? -20.203 30.070  13.727 1.00 8.90  ?  122  ALA A CA   1 
ATOM   1682  C C    . ALA A 1 156 ? -20.384 29.704  15.198 1.00 8.73  ?  122  ALA A C    1 
ATOM   1683  O O    . ALA A 1 156 ? -20.475 28.505  15.506 1.00 10.21 ?  122  ALA A O    1 
ATOM   1684  C CB   . ALA A 1 156 ? -18.790 29.682  13.305 1.00 10.16 ?  122  ALA A CB   1 
ATOM   1685  H H    . ALA A 1 156 ? -19.707 31.922  13.271 1.00 10.58 ?  122  ALA A H    1 
ATOM   1686  H HA   . ALA A 1 156 ? -20.848 29.559  13.214 1.00 10.67 ?  122  ALA A HA   1 
ATOM   1687  H HB1  . ALA A 1 156 ? -18.622 28.764  13.570 1.00 12.19 ?  122  ALA A HB1  1 
ATOM   1688  H HB2  . ALA A 1 156 ? -18.713 29.767  12.342 1.00 12.19 ?  122  ALA A HB2  1 
ATOM   1689  H HB3  . ALA A 1 156 ? -18.156 30.273  13.741 1.00 12.19 ?  122  ALA A HB3  1 
ATOM   1690  N N    . LEU A 1 157 ? -20.430 30.672  16.107 1.00 8.32  ?  123  LEU A N    1 
ATOM   1691  C CA   . LEU A 1 157 ? -20.513 30.381  17.534 1.00 9.37  ?  123  LEU A CA   1 
ATOM   1692  C C    . LEU A 1 157 ? -21.952 30.359  18.037 1.00 10.26 ?  123  LEU A C    1 
ATOM   1693  O O    . LEU A 1 157 ? -22.839 31.060  17.537 1.00 10.90 ?  123  LEU A O    1 
ATOM   1694  C CB   . LEU A 1 157 ? -19.697 31.388  18.342 1.00 9.68  ?  123  LEU A CB   1 
ATOM   1695  C CG   . LEU A 1 157 ? -18.193 31.369  18.085 1.00 8.67  ?  123  LEU A CG   1 
ATOM   1696  C CD1  . LEU A 1 157 ? -17.541 32.430  18.941 1.00 11.22 ?  123  LEU A CD1  1 
ATOM   1697  C CD2  . LEU A 1 157 ? -17.575 29.984  18.355 1.00 9.23  ?  123  LEU A CD2  1 
ATOM   1698  H H    . LEU A 1 157 ? -20.415 31.512  15.921 1.00 9.98  ?  123  LEU A H    1 
ATOM   1699  H HA   . LEU A 1 157 ? -20.147 29.494  17.681 1.00 11.25 ?  123  LEU A HA   1 
ATOM   1700  H HB2  . LEU A 1 157 ? -20.015 32.279  18.129 1.00 11.61 ?  123  LEU A HB2  1 
ATOM   1701  H HB3  . LEU A 1 157 ? -19.832 31.204  19.284 1.00 11.61 ?  123  LEU A HB3  1 
ATOM   1702  H HG   . LEU A 1 157 ? -18.025 31.558  17.149 1.00 10.40 ?  123  LEU A HG   1 
ATOM   1703  H HD11 . LEU A 1 157 ? -16.594 32.466  18.732 1.00 13.46 ?  123  LEU A HD11 1 
ATOM   1704  H HD12 . LEU A 1 157 ? -17.954 33.286  18.752 1.00 13.46 ?  123  LEU A HD12 1 
ATOM   1705  H HD13 . LEU A 1 157 ? -17.665 32.202  19.876 1.00 13.46 ?  123  LEU A HD13 1 
ATOM   1706  H HD21 . LEU A 1 157 ? -16.608 30.059  18.334 1.00 11.08 ?  123  LEU A HD21 1 
ATOM   1707  H HD22 . LEU A 1 157 ? -17.864 29.674  19.227 1.00 11.08 ?  123  LEU A HD22 1 
ATOM   1708  H HD23 . LEU A 1 157 ? -17.874 29.366  17.669 1.00 11.08 ?  123  LEU A HD23 1 
ATOM   1709  N N    . LEU A 1 158 ? -22.162 29.572  19.079 1.00 8.44  ?  124  LEU A N    1 
ATOM   1710  C CA   . LEU A 1 158 ? -23.485 29.298  19.628 1.00 8.29  ?  124  LEU A CA   1 
ATOM   1711  C C    . LEU A 1 158 ? -23.991 30.440  20.503 1.00 10.17 ?  124  LEU A C    1 
ATOM   1712  O O    . LEU A 1 158 ? -23.285 30.941  21.379 1.00 11.17 ?  124  LEU A O    1 
ATOM   1713  C CB   . LEU A 1 158 ? -23.417 28.017  20.453 1.00 7.78  ?  124  LEU A CB   1 
ATOM   1714  C CG   . LEU A 1 158 ? -24.712 27.545  21.102 1.00 8.46  ?  124  LEU A CG   1 
ATOM   1715  C CD1  . LEU A 1 158 ? -25.765 27.192  20.068 1.00 9.81  ?  124  LEU A CD1  1 
ATOM   1716  C CD2  . LEU A 1 158 ? -24.451 26.363  21.998 1.00 10.29 ?  124  LEU A CD2  1 
ATOM   1717  H H    . LEU A 1 158 ? -21.534 29.168  19.504 1.00 10.13 ?  124  LEU A H    1 
ATOM   1718  H HA   . LEU A 1 158 ? -24.115 29.201  18.897 1.00 9.95  ?  124  LEU A HA   1 
ATOM   1719  H HB2  . LEU A 1 158 ? -23.115 27.303  19.871 1.00 9.33  ?  124  LEU A HB2  1 
ATOM   1720  H HB3  . LEU A 1 158 ? -22.776 28.156  21.168 1.00 9.33  ?  124  LEU A HB3  1 
ATOM   1721  H HG   . LEU A 1 158 ? -25.062 28.274  21.638 1.00 10.15 ?  124  LEU A HG   1 
ATOM   1722  H HD11 . LEU A 1 158 ? -26.471 26.684  20.497 1.00 11.77 ?  124  LEU A HD11 1 
ATOM   1723  H HD12 . LEU A 1 158 ? -26.127 28.011  19.695 1.00 11.77 ?  124  LEU A HD12 1 
ATOM   1724  H HD13 . LEU A 1 158 ? -25.354 26.662  19.367 1.00 11.77 ?  124  LEU A HD13 1 
ATOM   1725  H HD21 . LEU A 1 158 ? -25.276 26.119  22.448 1.00 12.35 ?  124  LEU A HD21 1 
ATOM   1726  H HD22 . LEU A 1 158 ? -24.138 25.621  21.458 1.00 12.35 ?  124  LEU A HD22 1 
ATOM   1727  H HD23 . LEU A 1 158 ? -23.777 26.604  22.652 1.00 12.35 ?  124  LEU A HD23 1 
ATOM   1728  N N    . LYS A 1 159 ? -25.255 30.818  20.288 1.00 10.14 ?  125  LYS A N    1 
ATOM   1729  C CA   . LYS A 1 159 ? -25.915 31.870  21.039 1.00 11.07 ?  125  LYS A CA   1 
ATOM   1730  C C    . LYS A 1 159 ? -27.203 31.347  21.657 1.00 12.74 ?  125  LYS A C    1 
ATOM   1731  O O    . LYS A 1 159 ? -27.819 30.397  21.165 1.00 12.93 ?  125  LYS A O    1 
ATOM   1732  C CB   . LYS A 1 159 ? -26.243 33.027  20.097 1.00 14.15 ?  125  LYS A CB   1 
ATOM   1733  C CG   . LYS A 1 159 ? -25.042 33.875  19.793 1.00 14.46 ?  125  LYS A CG   1 
ATOM   1734  C CD   . LYS A 1 159 ? -25.288 34.924  18.715 1.00 21.18 ?  125  LYS A CD   1 
ATOM   1735  C CE   . LYS A 1 159 ? -23.969 35.629  18.410 1.00 26.22 ?  125  LYS A CE   1 
ATOM   1736  N NZ   . LYS A 1 159 ? -24.109 36.651  17.336 1.00 41.26 ?  125  LYS A NZ   1 
ATOM   1737  H H    . LYS A 1 159 ? -25.761 30.463  19.691 1.00 12.17 ?  125  LYS A H    1 
ATOM   1738  H HA   . LYS A 1 159 ? -25.347 32.178  21.762 1.00 13.28 ?  125  LYS A HA   1 
ATOM   1739  H HB2  . LYS A 1 159 ? -26.579 32.669  19.261 1.00 16.98 ?  125  LYS A HB2  1 
ATOM   1740  H HB3  . LYS A 1 159 ? -26.915 33.591  20.511 1.00 16.98 ?  125  LYS A HB3  1 
ATOM   1741  H HG2  . LYS A 1 159 ? -24.775 34.340  20.601 1.00 17.36 ?  125  LYS A HG2  1 
ATOM   1742  H HG3  . LYS A 1 159 ? -24.323 33.301  19.487 1.00 17.36 ?  125  LYS A HG3  1 
ATOM   1743  H HD2  . LYS A 1 159 ? -25.615 34.500  17.906 1.00 25.42 ?  125  LYS A HD2  1 
ATOM   1744  H HD3  . LYS A 1 159 ? -25.931 35.579  19.029 1.00 25.42 ?  125  LYS A HD3  1 
ATOM   1745  H HE2  . LYS A 1 159 ? -23.653 36.074  19.212 1.00 31.46 ?  125  LYS A HE2  1 
ATOM   1746  H HE3  . LYS A 1 159 ? -23.318 34.972  18.118 1.00 31.46 ?  125  LYS A HE3  1 
ATOM   1747  H HZ1  . LYS A 1 159 ? -23.326 37.048  17.189 1.00 49.51 ?  125  LYS A HZ1  1 
ATOM   1748  H HZ2  . LYS A 1 159 ? -24.383 36.266  16.582 1.00 49.51 ?  125  LYS A HZ2  1 
ATOM   1749  H HZ3  . LYS A 1 159 ? -24.704 37.268  17.578 1.00 49.51 ?  125  LYS A HZ3  1 
ATOM   1750  N N    . ASN A 1 160 ? -27.608 31.991  22.755 1.00 13.37 ?  126  ASN A N    1 
ATOM   1751  C CA   . ASN A 1 160 ? -28.878 31.700  23.395 1.00 13.71 ?  126  ASN A CA   1 
ATOM   1752  C C    . ASN A 1 160 ? -30.002 32.413  22.650 1.00 14.45 ?  126  ASN A C    1 
ATOM   1753  O O    . ASN A 1 160 ? -29.792 33.071  21.629 1.00 14.81 ?  126  ASN A O    1 
ATOM   1754  C CB   . ASN A 1 160 ? -28.847 32.032  24.889 1.00 13.52 ?  126  ASN A CB   1 
ATOM   1755  C CG   . ASN A 1 160 ? -28.707 33.511  25.182 1.00 15.66 ?  126  ASN A CG   1 
ATOM   1756  O OD1  . ASN A 1 160 ? -28.942 34.367  24.328 1.00 15.27 ?  126  ASN A OD1  1 
ATOM   1757  N ND2  . ASN A 1 160 ? -28.325 33.819  26.421 1.00 17.26 ?  126  ASN A ND2  1 
ATOM   1758  H H    . ASN A 1 160 ? -27.155 32.607  23.148 1.00 16.04 ?  126  ASN A H    1 
ATOM   1759  H HA   . ASN A 1 160 ? -29.043 30.746  23.342 1.00 16.46 ?  126  ASN A HA   1 
ATOM   1760  H HB2  . ASN A 1 160 ? -29.674 31.728  25.294 1.00 16.23 ?  126  ASN A HB2  1 
ATOM   1761  H HB3  . ASN A 1 160 ? -28.092 31.578  25.295 1.00 16.23 ?  126  ASN A HB3  1 
ATOM   1762  H HD21 . ASN A 1 160 ? -28.227 34.642  26.649 1.00 20.71 ?  126  ASN A HD21 1 
ATOM   1763  H HD22 . ASN A 1 160 ? -28.176 33.194  26.992 1.00 20.71 ?  126  ASN A HD22 1 
ATOM   1764  N N    . GLN A 1 161 ? -31.223 32.244  23.160 1.00 15.29 ?  127  GLN A N    1 
ATOM   1765  C CA   . GLN A 1 161 ? -32.402 32.761  22.477 1.00 19.50 ?  127  GLN A CA   1 
ATOM   1766  C C    . GLN A 1 161 ? -32.465 34.276  22.536 1.00 19.24 ?  127  GLN A C    1 
ATOM   1767  O O    . GLN A 1 161 ? -33.207 34.882  21.755 1.00 26.67 ?  127  GLN A O    1 
ATOM   1768  C CB   . GLN A 1 161 ? -33.664 32.130  23.068 1.00 16.74 ?  127  GLN A CB   1 
ATOM   1769  C CG   . GLN A 1 161 ? -33.876 30.681  22.669 1.00 16.39 ?  127  GLN A CG   1 
ATOM   1770  C CD   . GLN A 1 161 ? -34.872 29.984  23.573 1.00 15.63 ?  127  GLN A CD   1 
ATOM   1771  O OE1  . GLN A 1 161 ? -34.554 29.598  24.696 1.00 17.17 ?  127  GLN A OE1  1 
ATOM   1772  N NE2  . GLN A 1 161 ? -36.107 29.831  23.086 1.00 18.60 ?  127  GLN A NE2  1 
ATOM   1773  H H    . GLN A 1 161 ? -31.392 31.835  23.897 1.00 18.35 ?  127  GLN A H    1 
ATOM   1774  H HA   . GLN A 1 161 ? -32.374 32.510  21.541 1.00 23.39 ?  127  GLN A HA   1 
ATOM   1775  H HB2  . GLN A 1 161 ? -33.604 32.164  24.036 1.00 20.09 ?  127  GLN A HB2  1 
ATOM   1776  H HB3  . GLN A 1 161 ? -34.435 32.635  22.765 1.00 20.09 ?  127  GLN A HB3  1 
ATOM   1777  H HG2  . GLN A 1 161 ? -34.214 30.646  21.761 1.00 19.66 ?  127  GLN A HG2  1 
ATOM   1778  H HG3  . GLN A 1 161 ? -33.031 30.207  22.727 1.00 19.66 ?  127  GLN A HG3  1 
ATOM   1779  H HE21 . GLN A 1 161 ? -36.298 30.122  22.299 1.00 22.32 ?  127  GLN A HE21 1 
ATOM   1780  H HE22 . GLN A 1 161 ? -36.711 29.442  23.559 1.00 22.32 ?  127  GLN A HE22 1 
ATOM   1781  N N    . ASN A 1 162 ? -31.692 34.895  23.417 1.00 15.55 ?  128  ASN A N    1 
ATOM   1782  C CA   . ASN A 1 162 ? -31.540 36.340  23.480 1.00 20.78 ?  128  ASN A CA   1 
ATOM   1783  C C    . ASN A 1 162 ? -30.354 36.834  22.660 1.00 17.84 ?  128  ASN A C    1 
ATOM   1784  O O    . ASN A 1 162 ? -29.900 37.966  22.858 1.00 21.10 ?  128  ASN A O    1 
ATOM   1785  C CB   . ASN A 1 162 ? -31.372 36.793  24.933 1.00 22.82 ?  128  ASN A CB   1 
ATOM   1786  C CG   . ASN A 1 162 ? -31.826 38.220  25.150 1.00 37.05 ?  128  ASN A CG   1 
ATOM   1787  O OD1  . ASN A 1 162 ? -32.618 38.755  24.373 1.00 34.72 ?  128  ASN A OD1  1 
ATOM   1788  N ND2  . ASN A 1 162 ? -31.309 38.853  26.198 1.00 41.17 ?  128  ASN A ND2  1 
ATOM   1789  H H    . ASN A 1 162 ? -31.228 34.483  24.013 1.00 18.67 ?  128  ASN A H    1 
ATOM   1790  H HA   . ASN A 1 162 ? -32.347 36.748  23.129 1.00 24.93 ?  128  ASN A HA   1 
ATOM   1791  H HB2  . ASN A 1 162 ? -31.901 36.218  25.507 1.00 27.38 ?  128  ASN A HB2  1 
ATOM   1792  H HB3  . ASN A 1 162 ? -30.435 36.734  25.177 1.00 27.38 ?  128  ASN A HB3  1 
ATOM   1793  H HD21 . ASN A 1 162 ? -30.748 38.450  26.710 1.00 49.40 ?  128  ASN A HD21 1 
ATOM   1794  H HD22 . ASN A 1 162 ? -31.536 39.666  26.364 1.00 49.40 ?  128  ASN A HD22 1 
ATOM   1795  N N    . ASN A 1 163 ? -29.803 35.989  21.787 1.00 18.25 ?  129  ASN A N    1 
ATOM   1796  C CA   . ASN A 1 163 ? -28.713 36.370  20.894 1.00 17.17 ?  129  ASN A CA   1 
ATOM   1797  C C    . ASN A 1 163 ? -27.403 36.662  21.631 1.00 22.21 ?  129  ASN A C    1 
ATOM   1798  O O    . ASN A 1 163 ? -26.577 37.432  21.144 1.00 19.01 ?  129  ASN A O    1 
ATOM   1799  C CB   . ASN A 1 163 ? -29.113 37.565  20.015 1.00 21.26 ?  129  ASN A CB   1 
ATOM   1800  C CG   . ASN A 1 163 ? -28.229 37.723  18.798 1.00 32.27 ?  129  ASN A CG   1 
ATOM   1801  O OD1  . ASN A 1 163 ? -27.819 36.738  18.182 1.00 34.36 ?  129  ASN A OD1  1 
ATOM   1802  N ND2  . ASN A 1 163 ? -27.918 38.969  18.451 1.00 39.08 ?  129  ASN A ND2  1 
ATOM   1803  H H    . ASN A 1 163 ? -30.051 35.171  21.693 1.00 21.90 ?  129  ASN A H    1 
ATOM   1804  H HA   . ASN A 1 163 ? -28.533 35.612  20.315 1.00 20.60 ?  129  ASN A HA   1 
ATOM   1805  H HB2  . ASN A 1 163 ? -30.025 37.440  19.708 1.00 25.51 ?  129  ASN A HB2  1 
ATOM   1806  H HB3  . ASN A 1 163 ? -29.048 38.379  20.539 1.00 25.51 ?  129  ASN A HB3  1 
ATOM   1807  H HD21 . ASN A 1 163 ? -28.217 39.631  18.910 1.00 46.90 ?  129  ASN A HD21 1 
ATOM   1808  H HD22 . ASN A 1 163 ? -27.418 39.112  17.766 1.00 46.90 ?  129  ASN A HD22 1 
ATOM   1809  N N    . GLU A 1 164 ? -27.164 36.053  22.792 1.00 16.28 ?  130  GLU A N    1 
ATOM   1810  C CA   . GLU A 1 164 ? -25.907 36.223  23.508 1.00 15.35 ?  130  GLU A CA   1 
ATOM   1811  C C    . GLU A 1 164 ? -25.045 34.967  23.385 1.00 11.12 ?  130  GLU A C    1 
ATOM   1812  O O    . GLU A 1 164 ? -25.549 33.848  23.489 1.00 13.30 ?  130  GLU A O    1 
ATOM   1813  C CB   . GLU A 1 164 ? -26.113 36.542  24.996 1.00 17.14 ?  130  GLU A CB   1 
ATOM   1814  C CG   . GLU A 1 164 ? -27.085 37.708  25.259 1.00 20.78 ?  130  GLU A CG   1 
ATOM   1815  C CD   . GLU A 1 164 ? -27.744 37.672  26.633 1.00 28.75 ?  130  GLU A CD   1 
ATOM   1816  O OE1  . GLU A 1 164 ? -27.992 36.587  27.195 1.00 24.48 ?  130  GLU A OE1  1 
ATOM   1817  O OE2  . GLU A 1 164 ? -28.046 38.766  27.152 1.00 37.96 ?  130  GLU A OE2  1 
ATOM   1818  H H    . GLU A 1 164 ? -27.724 35.532  23.186 1.00 19.53 ?  130  GLU A H    1 
ATOM   1819  H HA   . GLU A 1 164 ? -25.437 36.968  23.103 1.00 18.42 ?  130  GLU A HA   1 
ATOM   1820  H HB2  . GLU A 1 164 ? -26.471 35.755  25.436 1.00 20.57 ?  130  GLU A HB2  1 
ATOM   1821  H HB3  . GLU A 1 164 ? -25.257 36.779  25.384 1.00 20.57 ?  130  GLU A HB3  1 
ATOM   1822  H HG2  . GLU A 1 164 ? -26.596 38.543  25.189 1.00 24.94 ?  130  GLU A HG2  1 
ATOM   1823  H HG3  . GLU A 1 164 ? -27.791 37.681  24.594 1.00 24.94 ?  130  GLU A HG3  1 
ATOM   1824  N N    . LEU A 1 165 ? -23.747 35.173  23.196 1.00 12.70 ?  131  LEU A N    1 
ATOM   1825  C CA   . LEU A 1 165 ? -22.818 34.049  23.216 1.00 12.83 ?  131  LEU A CA   1 
ATOM   1826  C C    . LEU A 1 165 ? -22.872 33.365  24.572 1.00 12.29 ?  131  LEU A C    1 
ATOM   1827  O O    . LEU A 1 165 ? -22.979 34.020  25.616 1.00 13.08 ?  131  LEU A O    1 
ATOM   1828  C CB   . LEU A 1 165 ? -21.405 34.529  22.974 1.00 12.61 ?  131  LEU A CB   1 
ATOM   1829  C CG   . LEU A 1 165 ? -21.126 34.947  21.531 1.00 13.99 ?  131  LEU A CG   1 
ATOM   1830  C CD1  . LEU A 1 165 ? -19.820 35.699  21.451 1.00 17.29 ?  131  LEU A CD1  1 
ATOM   1831  C CD2  . LEU A 1 165 ? -21.068 33.742  20.593 1.00 15.27 ?  131  LEU A CD2  1 
ATOM   1832  H H    . LEU A 1 165 ? -23.384 35.940  23.057 1.00 15.24 ?  131  LEU A H    1 
ATOM   1833  H HA   . LEU A 1 165 ? -23.060 33.421  22.518 1.00 15.40 ?  131  LEU A HA   1 
ATOM   1834  H HB2  . LEU A 1 165 ? -21.237 35.297  23.542 1.00 15.14 ?  131  LEU A HB2  1 
ATOM   1835  H HB3  . LEU A 1 165 ? -20.792 33.811  23.197 1.00 15.14 ?  131  LEU A HB3  1 
ATOM   1836  H HG   . LEU A 1 165 ? -21.854 35.520  21.242 1.00 16.79 ?  131  LEU A HG   1 
ATOM   1837  H HD11 . LEU A 1 165 ? -19.650 35.939  20.527 1.00 20.75 ?  131  LEU A HD11 1 
ATOM   1838  H HD12 . LEU A 1 165 ? -19.883 36.500  21.994 1.00 20.75 ?  131  LEU A HD12 1 
ATOM   1839  H HD13 . LEU A 1 165 ? -19.107 35.130  21.781 1.00 20.75 ?  131  LEU A HD13 1 
ATOM   1840  H HD21 . LEU A 1 165 ? -20.888 34.052  19.691 1.00 18.32 ?  131  LEU A HD21 1 
ATOM   1841  H HD22 . LEU A 1 165 ? -20.359 33.148  20.886 1.00 18.32 ?  131  LEU A HD22 1 
ATOM   1842  H HD23 . LEU A 1 165 ? -21.919 33.279  20.620 1.00 18.32 ?  131  LEU A HD23 1 
ATOM   1843  N N    . VAL A 1 166 ? -22.800 32.037  24.551 1.00 10.13 ?  132  VAL A N    1 
ATOM   1844  C CA   . VAL A 1 166 ? -22.748 31.243  25.772 1.00 10.46 ?  132  VAL A CA   1 
ATOM   1845  C C    . VAL A 1 166 ? -21.376 30.583  25.893 1.00 7.94  ?  132  VAL A C    1 
ATOM   1846  O O    . VAL A 1 166 ? -20.664 30.359  24.906 1.00 9.03  ?  132  VAL A O    1 
ATOM   1847  C CB   . VAL A 1 166 ? -23.896 30.221  25.883 1.00 10.98 ?  132  VAL A CB   1 
ATOM   1848  C CG1  . VAL A 1 166 ? -25.235 30.957  25.913 1.00 12.60 ?  132  VAL A CG1  1 
ATOM   1849  C CG2  . VAL A 1 166 ? -23.847 29.234  24.756 1.00 10.52 ?  132  VAL A CG2  1 
ATOM   1850  H H    . VAL A 1 166 ? -22.780 31.567  23.831 1.00 12.15 ?  132  VAL A H    1 
ATOM   1851  H HA   . VAL A 1 166 ? -22.841 31.845  26.527 1.00 12.56 ?  132  VAL A HA   1 
ATOM   1852  H HB   . VAL A 1 166 ? -23.801 29.718  26.707 1.00 13.17 ?  132  VAL A HB   1 
ATOM   1853  H HG11 . VAL A 1 166 ? -25.938 30.325  26.131 1.00 15.12 ?  132  VAL A HG11 1 
ATOM   1854  H HG12 . VAL A 1 166 ? -25.197 31.655  26.585 1.00 15.12 ?  132  VAL A HG12 1 
ATOM   1855  H HG13 . VAL A 1 166 ? -25.400 31.347  25.040 1.00 15.12 ?  132  VAL A HG13 1 
ATOM   1856  H HG21 . VAL A 1 166 ? -24.601 28.629  24.832 1.00 12.63 ?  132  VAL A HG21 1 
ATOM   1857  H HG22 . VAL A 1 166 ? -23.890 29.713  23.914 1.00 12.63 ?  132  VAL A HG22 1 
ATOM   1858  H HG23 . VAL A 1 166 ? -23.017 28.734  24.809 1.00 12.63 ?  132  VAL A HG23 1 
ATOM   1859  N N    . TYR A 1 167 ? -20.998 30.275  27.126 1.00 9.65  ?  133  TYR A N    1 
ATOM   1860  C CA   . TYR A 1 167 ? -19.623 29.913  27.425 1.00 9.15  ?  133  TYR A CA   1 
ATOM   1861  C C    . TYR A 1 167 ? -19.539 28.752  28.395 1.00 8.92  ?  133  TYR A C    1 
ATOM   1862  O O    . TYR A 1 167 ? -20.480 28.438  29.128 1.00 9.91  ?  133  TYR A O    1 
ATOM   1863  C CB   . TYR A 1 167 ? -18.878 31.097  28.077 1.00 10.33 ?  133  TYR A CB   1 
ATOM   1864  C CG   . TYR A 1 167 ? -18.721 32.252  27.153 1.00 10.18 ?  133  TYR A CG   1 
ATOM   1865  C CD1  . TYR A 1 167 ? -17.716 32.264  26.209 1.00 11.26 ?  133  TYR A CD1  1 
ATOM   1866  C CD2  . TYR A 1 167 ? -19.611 33.322  27.184 1.00 13.13 ?  133  TYR A CD2  1 
ATOM   1867  C CE1  . TYR A 1 167 ? -17.582 33.304  25.322 1.00 14.58 ?  133  TYR A CE1  1 
ATOM   1868  C CE2  . TYR A 1 167 ? -19.478 34.364  26.291 1.00 14.22 ?  133  TYR A CE2  1 
ATOM   1869  C CZ   . TYR A 1 167 ? -18.453 34.342  25.377 1.00 14.96 ?  133  TYR A CZ   1 
ATOM   1870  O OH   . TYR A 1 167 ? -18.282 35.382  24.466 1.00 20.48 ?  133  TYR A OH   1 
ATOM   1871  H H    . TYR A 1 167 ? -21.522 30.268  27.808 1.00 11.58 ?  133  TYR A H    1 
ATOM   1872  H HA   . TYR A 1 167 ? -19.213 29.640  26.590 1.00 10.97 ?  133  TYR A HA   1 
ATOM   1873  H HB2  . TYR A 1 167 ? -19.377 31.397  28.852 1.00 12.40 ?  133  TYR A HB2  1 
ATOM   1874  H HB3  . TYR A 1 167 ? -17.993 30.804  28.345 1.00 12.40 ?  133  TYR A HB3  1 
ATOM   1875  H HD1  . TYR A 1 167 ? -17.116 31.554  26.172 1.00 13.51 ?  133  TYR A HD1  1 
ATOM   1876  H HD2  . TYR A 1 167 ? -20.298 33.333  27.810 1.00 15.76 ?  133  TYR A HD2  1 
ATOM   1877  H HE1  . TYR A 1 167 ? -16.900 33.297  24.690 1.00 17.50 ?  133  TYR A HE1  1 
ATOM   1878  H HE2  . TYR A 1 167 ? -20.077 35.075  26.307 1.00 17.06 ?  133  TYR A HE2  1 
ATOM   1879  H HH   . TYR A 1 167 ? -17.680 35.184  23.915 1.00 24.58 ?  133  TYR A HH   1 
ATOM   1880  N N    . MET A 1 168 ? -18.347 28.157  28.422 1.00 8.85  ?  134  MET A N    1 
ATOM   1881  C CA   . MET A 1 168 ? -17.983 27.173  29.411 1.00 7.97  ?  134  MET A CA   1 
ATOM   1882  C C    . MET A 1 168 ? -17.805 27.887  30.759 1.00 8.75  ?  134  MET A C    1 
ATOM   1883  O O    . MET A 1 168 ? -17.898 29.118  30.821 1.00 8.48  ?  134  MET A O    1 
ATOM   1884  C CB   . MET A 1 168 ? -16.681 26.480  29.019 1.00 8.19  ?  134  MET A CB   1 
ATOM   1885  C CG   . MET A 1 168 ? -16.996 25.533  27.888 1.00 11.26 ?  134  MET A CG   1 
ATOM   1886  S SD   . MET A 1 168 ? -17.732 24.003  28.398 1.00 9.62  ?  134  MET A SD   1 
ATOM   1887  C CE   . MET A 1 168 ? -16.370 23.237  29.359 1.00 10.66 ?  134  MET A CE   1 
ATOM   1888  H H    . MET A 1 168 ? -17.719 28.318  27.857 1.00 10.62 ?  134  MET A H    1 
ATOM   1889  H HA   . MET A 1 168 ? -18.674 26.496  29.474 1.00 9.57  ?  134  MET A HA   1 
ATOM   1890  H HB2  . MET A 1 168 ? -16.029 27.133  28.720 1.00 9.82  ?  134  MET A HB2  1 
ATOM   1891  H HB3  . MET A 1 168 ? -16.328 25.979  29.771 1.00 9.82  ?  134  MET A HB3  1 
ATOM   1892  H HG2  . MET A 1 168 ? -17.616 25.969  27.283 1.00 13.51 ?  134  MET A HG2  1 
ATOM   1893  H HG3  . MET A 1 168 ? -16.172 25.321  27.423 1.00 13.51 ?  134  MET A HG3  1 
ATOM   1894  H HE1  . MET A 1 168 ? -16.671 22.384  29.710 1.00 12.80 ?  134  MET A HE1  1 
ATOM   1895  H HE2  . MET A 1 168 ? -15.607 23.103  28.774 1.00 12.80 ?  134  MET A HE2  1 
ATOM   1896  H HE3  . MET A 1 168 ? -16.127 23.828  30.088 1.00 12.80 ?  134  MET A HE3  1 
ATOM   1897  N N    . PRO A 1 169 ? -17.554 27.154  31.850 1.00 7.76  ?  135  PRO A N    1 
ATOM   1898  C CA   . PRO A 1 169 ? -17.450 27.806  33.168 1.00 8.60  ?  135  PRO A CA   1 
ATOM   1899  C C    . PRO A 1 169 ? -16.361 28.851  33.283 1.00 8.98  ?  135  PRO A C    1 
ATOM   1900  O O    . PRO A 1 169 ? -16.460 29.721  34.170 1.00 10.02 ?  135  PRO A O    1 
ATOM   1901  C CB   . PRO A 1 169 ? -17.251 26.621  34.129 1.00 11.07 ?  135  PRO A CB   1 
ATOM   1902  C CG   . PRO A 1 169 ? -17.989 25.483  33.437 1.00 11.33 ?  135  PRO A CG   1 
ATOM   1903  C CD   . PRO A 1 169 ? -17.635 25.679  31.980 1.00 9.37  ?  135  PRO A CD   1 
ATOM   1904  H HA   . PRO A 1 169 ? -18.290 28.243  33.382 1.00 10.32 ?  135  PRO A HA   1 
ATOM   1905  H HB2  . PRO A 1 169 ? -16.307 26.421  34.227 1.00 13.28 ?  135  PRO A HB2  1 
ATOM   1906  H HB3  . PRO A 1 169 ? -17.639 26.820  34.995 1.00 13.28 ?  135  PRO A HB3  1 
ATOM   1907  H HG2  . PRO A 1 169 ? -17.674 24.626  33.766 1.00 13.60 ?  135  PRO A HG2  1 
ATOM   1908  H HG3  . PRO A 1 169 ? -18.945 25.563  33.583 1.00 13.60 ?  135  PRO A HG3  1 
ATOM   1909  H HD2  . PRO A 1 169 ? -16.782 25.266  31.772 1.00 11.24 ?  135  PRO A HD2  1 
ATOM   1910  H HD3  . PRO A 1 169 ? -18.327 25.318  31.404 1.00 11.24 ?  135  PRO A HD3  1 
ATOM   1911  N N    . ASN A 1 170 ? -15.335 28.837  32.437 1.00 8.78  ?  136  ASN A N    1 
ATOM   1912  C CA   . ASN A 1 170 ? -14.331 29.895  32.469 1.00 8.40  ?  136  ASN A CA   1 
ATOM   1913  C C    . ASN A 1 170 ? -14.855 31.221  31.938 1.00 8.45  ?  136  ASN A C    1 
ATOM   1914  O O    . ASN A 1 170 ? -14.160 32.238  32.072 1.00 9.43  ?  136  ASN A O    1 
ATOM   1915  C CB   . ASN A 1 170 ? -13.039 29.488  31.760 1.00 9.39  ?  136  ASN A CB   1 
ATOM   1916  C CG   . ASN A 1 170 ? -13.241 29.156  30.298 1.00 10.47 ?  136  ASN A CG   1 
ATOM   1917  O OD1  . ASN A 1 170 ? -14.204 29.591  29.676 1.00 8.71  ?  136  ASN A OD1  1 
ATOM   1918  N ND2  . ASN A 1 170 ? -12.311 28.391  29.730 1.00 10.50 ?  136  ASN A ND2  1 
ATOM   1919  H H    . ASN A 1 170 ? -15.199 28.233  31.840 1.00 10.54 ?  136  ASN A H    1 
ATOM   1920  H HA   . ASN A 1 170 ? -14.079 30.031  33.396 1.00 10.08 ?  136  ASN A HA   1 
ATOM   1921  H HB2  . ASN A 1 170 ? -12.406 30.220  31.815 1.00 11.27 ?  136  ASN A HB2  1 
ATOM   1922  H HB3  . ASN A 1 170 ? -12.675 28.701  32.197 1.00 11.27 ?  136  ASN A HB3  1 
ATOM   1923  H HD21 . ASN A 1 170 ? -12.380 28.174  28.901 1.00 12.60 ?  136  ASN A HD21 1 
ATOM   1924  H HD22 . ASN A 1 170 ? -11.641 28.113  30.193 1.00 12.60 ?  136  ASN A HD22 1 
ATOM   1925  N N    . GLY A 1 171 ? -16.057 31.246  31.371 1.00 8.46  ?  137  GLY A N    1 
ATOM   1926  C CA   . GLY A 1 171 ? -16.631 32.488  30.888 1.00 8.33  ?  137  GLY A CA   1 
ATOM   1927  C C    . GLY A 1 171 ? -16.012 33.040  29.634 1.00 8.71  ?  137  GLY A C    1 
ATOM   1928  O O    . GLY A 1 171 ? -16.332 34.175  29.239 1.00 9.88  ?  137  GLY A O    1 
ATOM   1929  H H    . GLY A 1 171 ? -16.558 30.556  31.256 1.00 10.15 ?  137  GLY A H    1 
ATOM   1930  H HA2  . GLY A 1 171 ? -17.574 32.344  30.711 1.00 10.00 ?  137  GLY A HA2  1 
ATOM   1931  H HA3  . GLY A 1 171 ? -16.540 33.160  31.581 1.00 10.00 ?  137  GLY A HA3  1 
ATOM   1932  N N    . SER A 1 172 ? -15.138 32.291  28.975 1.00 8.35  ?  138  SER A N    1 
ATOM   1933  C CA   . SER A 1 172 ? -14.461 32.787  27.780 1.00 9.49  ?  138  SER A CA   1 
ATOM   1934  C C    . SER A 1 172 ? -14.362 31.781  26.652 1.00 9.42  ?  138  SER A C    1 
ATOM   1935  O O    . SER A 1 172 ? -14.251 32.209  25.504 1.00 10.57 ?  138  SER A O    1 
ATOM   1936  C CB   . SER A 1 172 ? -13.069 33.326  28.113 1.00 17.52 ?  138  SER A CB   1 
ATOM   1937  O OG   . SER A 1 172 ? -12.292 32.367  28.749 1.00 21.61 ?  138  SER A OG   1 
ATOM   1938  H H    . SER A 1 172 ? -14.918 31.490  29.198 1.00 10.02 ?  138  SER A H    1 
ATOM   1939  H HA   . SER A 1 172 ? -14.969 33.541  27.440 1.00 11.39 ?  138  SER A HA   1 
ATOM   1940  H HB2  . SER A 1 172 ? -12.629 33.590  27.290 1.00 21.02 ?  138  SER A HB2  1 
ATOM   1941  H HB3  . SER A 1 172 ? -13.161 34.094  28.700 1.00 21.02 ?  138  SER A HB3  1 
ATOM   1942  H HG   . SER A 1 172 ? -11.488 32.449  28.519 1.00 25.93 ?  138  SER A HG   1 
ATOM   1943  N N    . THR A 1 173 ? -14.427 30.477  26.905 1.00 8.55  ?  139  THR A N    1 
ATOM   1944  C CA   . THR A 1 173 ? -14.392 29.484  25.841 1.00 7.89  ?  139  THR A CA   1 
ATOM   1945  C C    . THR A 1 173 ? -15.816 29.255  25.346 1.00 7.35  ?  139  THR A C    1 
ATOM   1946  O O    . THR A 1 173 ? -16.667 28.818  26.127 1.00 8.17  ?  139  THR A O    1 
ATOM   1947  C CB   . THR A 1 173 ? -13.813 28.178  26.357 1.00 7.57  ?  139  THR A CB   1 
ATOM   1948  O OG1  . THR A 1 173 ? -12.496 28.396  26.871 1.00 9.13  ?  139  THR A OG1  1 
ATOM   1949  C CG2  . THR A 1 173 ? -13.765 27.106  25.260 1.00 8.41  ?  139  THR A CG2  1 
ATOM   1950  H H    . THR A 1 173 ? -14.493 30.140  27.694 1.00 10.26 ?  139  THR A H    1 
ATOM   1951  H HA   . THR A 1 173 ? -13.842 29.795  25.105 1.00 9.47  ?  139  THR A HA   1 
ATOM   1952  H HB   . THR A 1 173 ? -14.387 27.848  27.066 1.00 9.08  ?  139  THR A HB   1 
ATOM   1953  H HG1  . THR A 1 173 ? -11.989 28.661  26.257 1.00 10.95 ?  139  THR A HG1  1 
ATOM   1954  H HG21 . THR A 1 173 ? -13.383 26.287  25.614 1.00 10.10 ?  139  THR A HG21 1 
ATOM   1955  H HG22 . THR A 1 173 ? -14.661 26.921  24.937 1.00 10.10 ?  139  THR A HG22 1 
ATOM   1956  H HG23 . THR A 1 173 ? -13.220 27.413  24.519 1.00 10.10 ?  139  THR A HG23 1 
ATOM   1957  N N    . PRO A 1 174 ? -16.109 29.548  24.072 1.00 7.39  ?  140  PRO A N    1 
ATOM   1958  C CA   . PRO A 1 174 ? -17.462 29.395  23.530 1.00 7.74  ?  140  PRO A CA   1 
ATOM   1959  C C    . PRO A 1 174 ? -17.640 28.047  22.853 1.00 6.49  ?  140  PRO A C    1 
ATOM   1960  O O    . PRO A 1 174 ? -16.786 27.166  22.980 1.00 8.08  ?  140  PRO A O    1 
ATOM   1961  C CB   . PRO A 1 174 ? -17.528 30.540  22.517 1.00 8.86  ?  140  PRO A CB   1 
ATOM   1962  C CG   . PRO A 1 174 ? -16.140 30.547  21.939 1.00 9.44  ?  140  PRO A CG   1 
ATOM   1963  C CD   . PRO A 1 174 ? -15.191 30.130  23.079 1.00 7.86  ?  140  PRO A CD   1 
ATOM   1964  H HA   . PRO A 1 174 ? -18.141 29.512  24.213 1.00 9.28  ?  140  PRO A HA   1 
ATOM   1965  H HB2  . PRO A 1 174 ? -18.196 30.356  21.839 1.00 10.64 ?  140  PRO A HB2  1 
ATOM   1966  H HB3  . PRO A 1 174 ? -17.731 31.377  22.964 1.00 10.64 ?  140  PRO A HB3  1 
ATOM   1967  H HG2  . PRO A 1 174 ? -16.091 29.914  21.205 1.00 11.33 ?  140  PRO A HG2  1 
ATOM   1968  H HG3  . PRO A 1 174 ? -15.924 31.438  21.623 1.00 11.33 ?  140  PRO A HG3  1 
ATOM   1969  H HD2  . PRO A 1 174 ? -14.549 29.471  22.772 1.00 9.43  ?  140  PRO A HD2  1 
ATOM   1970  H HD3  . PRO A 1 174 ? -14.728 30.900  23.444 1.00 9.43  ?  140  PRO A HD3  1 
ATOM   1971  N N    . PHE A 1 175 ? -18.786 27.857  22.189 1.00 6.88  ?  141  PHE A N    1 
ATOM   1972  C CA   . PHE A 1 175 ? -19.157 26.611  21.541 1.00 7.49  ?  141  PHE A CA   1 
ATOM   1973  C C    . PHE A 1 175 ? -19.410 26.828  20.057 1.00 9.18  ?  141  PHE A C    1 
ATOM   1974  O O    . PHE A 1 175 ? -19.907 27.885  19.636 1.00 8.50  ?  141  PHE A O    1 
ATOM   1975  C CB   . PHE A 1 175 ? -20.455 26.045  22.136 1.00 8.30  ?  141  PHE A CB   1 
ATOM   1976  C CG   . PHE A 1 175 ? -20.419 25.814  23.620 1.00 7.00  ?  141  PHE A CG   1 
ATOM   1977  C CD1  . PHE A 1 175 ? -20.789 26.813  24.493 1.00 8.24  ?  141  PHE A CD1  1 
ATOM   1978  C CD2  . PHE A 1 175 ? -20.038 24.589  24.154 1.00 7.11  ?  141  PHE A CD2  1 
ATOM   1979  C CE1  . PHE A 1 175 ? -20.786 26.602  25.863 1.00 8.94  ?  141  PHE A CE1  1 
ATOM   1980  C CE2  . PHE A 1 175 ? -20.035 24.372  25.522 1.00 8.14  ?  141  PHE A CE2  1 
ATOM   1981  C CZ   . PHE A 1 175 ? -20.410 25.389  26.375 1.00 8.26  ?  141  PHE A CZ   1 
ATOM   1982  H H    . PHE A 1 175 ? -19.386 28.467  22.101 1.00 8.26  ?  141  PHE A H    1 
ATOM   1983  H HA   . PHE A 1 175 ? -18.426 25.984  21.656 1.00 8.98  ?  141  PHE A HA   1 
ATOM   1984  H HB2  . PHE A 1 175 ? -21.175 26.669  21.955 1.00 9.96  ?  141  PHE A HB2  1 
ATOM   1985  H HB3  . PHE A 1 175 ? -20.641 25.192  21.713 1.00 9.96  ?  141  PHE A HB3  1 
ATOM   1986  H HD1  . PHE A 1 175 ? -21.044 27.642  24.158 1.00 9.89  ?  141  PHE A HD1  1 
ATOM   1987  H HD2  . PHE A 1 175 ? -19.780 23.902  23.582 1.00 8.53  ?  141  PHE A HD2  1 
ATOM   1988  H HE1  . PHE A 1 175 ? -21.041 27.288  26.437 1.00 10.73 ?  141  PHE A HE1  1 
ATOM   1989  H HE2  . PHE A 1 175 ? -19.781 23.545  25.864 1.00 9.77  ?  141  PHE A HE2  1 
ATOM   1990  H HZ   . PHE A 1 175 ? -20.408 25.252  27.295 1.00 9.91  ?  141  PHE A HZ   1 
ATOM   1991  N N    . PHE A 1 176 ? -19.074 25.820  19.258 1.00 8.02  ?  142  PHE A N    1 
ATOM   1992  C CA   . PHE A 1 176 ? -19.481 25.817  17.860 1.00 8.49  ?  142  PHE A CA   1 
ATOM   1993  C C    . PHE A 1 176 ? -20.991 25.632  17.782 1.00 9.67  ?  142  PHE A C    1 
ATOM   1994  O O    . PHE A 1 176 ? -21.544 24.745  18.444 1.00 10.48 ?  142  PHE A O    1 
ATOM   1995  C CB   . PHE A 1 176 ? -18.841 24.636  17.127 1.00 8.40  ?  142  PHE A CB   1 
ATOM   1996  C CG   . PHE A 1 176 ? -17.342 24.608  17.130 1.00 9.64  ?  142  PHE A CG   1 
ATOM   1997  C CD1  . PHE A 1 176 ? -16.595 25.588  16.531 1.00 10.88 ?  142  PHE A CD1  1 
ATOM   1998  C CD2  . PHE A 1 176 ? -16.684 23.536  17.701 1.00 9.30  ?  142  PHE A CD2  1 
ATOM   1999  C CE1  . PHE A 1 176 ? -15.203 25.516  16.531 1.00 11.91 ?  142  PHE A CE1  1 
ATOM   2000  C CE2  . PHE A 1 176 ? -15.284 23.468  17.691 1.00 10.19 ?  142  PHE A CE2  1 
ATOM   2001  C CZ   . PHE A 1 176 ? -14.569 24.458  17.123 1.00 11.40 ?  142  PHE A CZ   1 
ATOM   2002  H H    . PHE A 1 176 ? -18.617 25.133  19.499 1.00 9.62  ?  142  PHE A H    1 
ATOM   2003  H HA   . PHE A 1 176 ? -19.209 26.649  17.441 1.00 10.19 ?  142  PHE A HA   1 
ATOM   2004  H HB2  . PHE A 1 176 ? -19.146 23.816  17.547 1.00 10.08 ?  142  PHE A HB2  1 
ATOM   2005  H HB3  . PHE A 1 176 ? -19.127 24.661  16.201 1.00 10.08 ?  142  PHE A HB3  1 
ATOM   2006  H HD1  . PHE A 1 176 ? -17.019 26.307  16.120 1.00 13.05 ?  142  PHE A HD1  1 
ATOM   2007  H HD2  . PHE A 1 176 ? -17.175 22.852  18.095 1.00 11.16 ?  142  PHE A HD2  1 
ATOM   2008  H HE1  . PHE A 1 176 ? -14.703 26.189  16.128 1.00 14.30 ?  142  PHE A HE1  1 
ATOM   2009  H HE2  . PHE A 1 176 ? -14.851 22.741  18.076 1.00 12.22 ?  142  PHE A HE2  1 
ATOM   2010  H HZ   . PHE A 1 176 ? -13.639 24.422  17.134 1.00 13.67 ?  142  PHE A HZ   1 
ATOM   2011  N N    . ASP A 1 177 ? -21.659 26.426  16.925 1.00 8.18  ?  143  ASP A N    1 
ATOM   2012  C CA   . ASP A 1 177 ? -23.074 26.170  16.639 1.00 8.79  ?  143  ASP A CA   1 
ATOM   2013  C C    . ASP A 1 177 ? -23.154 25.154  15.512 1.00 7.48  ?  143  ASP A C    1 
ATOM   2014  O O    . ASP A 1 177 ? -23.240 25.501  14.331 1.00 9.16  ?  143  ASP A O    1 
ATOM   2015  C CB   . ASP A 1 177 ? -23.860 27.426  16.284 1.00 8.64  ?  143  ASP A CB   1 
ATOM   2016  C CG   . ASP A 1 177 ? -25.347 27.126  16.148 1.00 9.66  ?  143  ASP A CG   1 
ATOM   2017  O OD1  . ASP A 1 177 ? -25.709 25.941  16.198 1.00 8.96  ?  143  ASP A OD1  1 
ATOM   2018  O OD2  . ASP A 1 177 ? -26.138 28.092  16.007 1.00 9.78  ?  143  ASP A OD2  1 
ATOM   2019  H H    . ASP A 1 177 ? -21.320 27.099  16.511 1.00 9.82  ?  143  ASP A H    1 
ATOM   2020  H HA   . ASP A 1 177 ? -23.463 25.806  17.449 1.00 10.54 ?  143  ASP A HA   1 
ATOM   2021  H HB2  . ASP A 1 177 ? -23.743 28.088  16.983 1.00 10.37 ?  143  ASP A HB2  1 
ATOM   2022  H HB3  . ASP A 1 177 ? -23.540 27.777  15.438 1.00 10.37 ?  143  ASP A HB3  1 
ATOM   2023  N N    . ILE A 1 178 ? -23.164 23.882  15.887 1.00 8.44  ?  144  ILE A N    1 
ATOM   2024  C CA   . ILE A 1 178 ? -23.113 22.805  14.914 1.00 7.76  ?  144  ILE A CA   1 
ATOM   2025  C C    . ILE A 1 178 ? -24.439 22.627  14.184 1.00 8.79  ?  144  ILE A C    1 
ATOM   2026  O O    . ILE A 1 178 ? -24.528 21.795  13.280 1.00 9.11  ?  144  ILE A O    1 
ATOM   2027  C CB   . ILE A 1 178 ? -22.632 21.473  15.525 1.00 8.04  ?  144  ILE A CB   1 
ATOM   2028  C CG1  . ILE A 1 178 ? -23.545 20.985  16.642 1.00 8.20  ?  144  ILE A CG1  1 
ATOM   2029  C CG2  . ILE A 1 178 ? -21.187 21.608  16.019 1.00 8.64  ?  144  ILE A CG2  1 
ATOM   2030  C CD1  . ILE A 1 178 ? -23.217 19.574  17.084 1.00 10.27 ?  144  ILE A CD1  1 
ATOM   2031  H H    . ILE A 1 178 ? -23.200 23.616  16.704 1.00 10.12 ?  144  ILE A H    1 
ATOM   2032  H HA   . ILE A 1 178 ? -22.466 23.083  14.247 1.00 9.31  ?  144  ILE A HA   1 
ATOM   2033  H HB   . ILE A 1 178 ? -22.667 20.805  14.823 1.00 9.65  ?  144  ILE A HB   1 
ATOM   2034  H HG12 . ILE A 1 178 ? -23.449 21.571  17.409 1.00 9.85  ?  144  ILE A HG12 1 
ATOM   2035  H HG13 . ILE A 1 178 ? -24.463 20.997  16.329 1.00 9.85  ?  144  ILE A HG13 1 
ATOM   2036  H HG21 . ILE A 1 178 ? -20.923 20.781  16.453 1.00 10.36 ?  144  ILE A HG21 1 
ATOM   2037  H HG22 . ILE A 1 178 ? -20.609 21.783  15.260 1.00 10.36 ?  144  ILE A HG22 1 
ATOM   2038  H HG23 . ILE A 1 178 ? -21.136 22.343  16.650 1.00 10.36 ?  144  ILE A HG23 1 
ATOM   2039  H HD11 . ILE A 1 178 ? -23.929 19.249  17.657 1.00 12.33 ?  144  ILE A HD11 1 
ATOM   2040  H HD12 . ILE A 1 178 ? -23.139 19.008  16.300 1.00 12.33 ?  144  ILE A HD12 1 
ATOM   2041  H HD13 . ILE A 1 178 ? -22.379 19.583  17.571 1.00 12.33 ?  144  ILE A HD13 1 
ATOM   2042  N N    . THR A 1 179 ? -25.463 23.408  14.542 1.00 8.85  ?  145  THR A N    1 
ATOM   2043  C CA   . THR A 1 179 ? -26.708 23.339  13.782 1.00 9.00  ?  145  THR A CA   1 
ATOM   2044  C C    . THR A 1 179 ? -26.585 24.018  12.434 1.00 10.46 ?  145  THR A C    1 
ATOM   2045  O O    . THR A 1 179 ? -27.428 23.773  11.560 1.00 10.66 ?  145  THR A O    1 
ATOM   2046  C CB   . THR A 1 179 ? -27.873 23.983  14.530 1.00 9.18  ?  145  THR A CB   1 
ATOM   2047  O OG1  . THR A 1 179 ? -27.703 25.398  14.575 1.00 9.66  ?  145  THR A OG1  1 
ATOM   2048  C CG2  . THR A 1 179 ? -28.029 23.402  15.916 1.00 11.04 ?  145  THR A CG2  1 
ATOM   2049  H H    . THR A 1 179 ? -25.460 23.965  15.197 1.00 10.62 ?  145  THR A H    1 
ATOM   2050  H HA   . THR A 1 179 ? -26.916 22.399  13.665 1.00 10.80 ?  145  THR A HA   1 
ATOM   2051  H HB   . THR A 1 179 ? -28.700 23.795  14.059 1.00 11.01 ?  145  THR A HB   1 
ATOM   2052  H HG1  . THR A 1 179 ? -27.505 25.639  15.355 1.00 11.59 ?  145  THR A HG1  1 
ATOM   2053  H HG21 . THR A 1 179 ? -28.830 23.753  16.336 1.00 13.24 ?  145  THR A HG21 1 
ATOM   2054  H HG22 . THR A 1 179 ? -28.099 22.435  15.865 1.00 13.24 ?  145  THR A HG22 1 
ATOM   2055  H HG23 . THR A 1 179 ? -27.261 23.633  16.462 1.00 13.24 ?  145  THR A HG23 1 
ATOM   2056  N N    . LYS A 1 180 ? -25.557 24.843  12.237 1.00 10.05 ?  146  LYS A N    1 
ATOM   2057  C CA   . LYS A 1 180 ? -25.358 25.552  10.979 1.00 10.35 ?  146  LYS A CA   1 
ATOM   2058  C C    . LYS A 1 180 ? -24.558 24.704  9.999  1.00 10.75 ?  146  LYS A C    1 
ATOM   2059  O O    . LYS A 1 180 ? -23.515 24.139  10.347 1.00 9.88  ?  146  LYS A O    1 
ATOM   2060  C CB   . LYS A 1 180 ? -24.655 26.880  11.241 1.00 10.24 ?  146  LYS A CB   1 
ATOM   2061  C CG   . LYS A 1 180 ? -25.569 27.844  12.024 1.00 14.13 ?  146  LYS A CG   1 
ATOM   2062  C CD   . LYS A 1 180 ? -24.962 29.203  12.290 1.00 11.75 ?  146  LYS A CD   1 
ATOM   2063  C CE   . LYS A 1 180 ? -26.038 30.255  12.600 1.00 14.23 ?  146  LYS A CE   1 
ATOM   2064  N NZ   . LYS A 1 180 ? -26.865 29.855  13.753 1.00 14.55 ?  146  LYS A NZ   1 
ATOM   2065  H H    . LYS A 1 180 ? -24.953 25.009  12.827 1.00 12.06 ?  146  LYS A H    1 
ATOM   2066  H HA   . LYS A 1 180 ? -26.218 25.727  10.568 1.00 12.42 ?  146  LYS A HA   1 
ATOM   2067  H HB2  . LYS A 1 180 ? -23.853 26.722  11.764 1.00 12.29 ?  146  LYS A HB2  1 
ATOM   2068  H HB3  . LYS A 1 180 ? -24.423 27.294  10.395 1.00 12.29 ?  146  LYS A HB3  1 
ATOM   2069  H HG2  . LYS A 1 180 ? -26.383 27.982  11.515 1.00 16.95 ?  146  LYS A HG2  1 
ATOM   2070  H HG3  . LYS A 1 180 ? -25.779 27.444  12.882 1.00 16.95 ?  146  LYS A HG3  1 
ATOM   2071  H HD2  . LYS A 1 180 ? -24.366 29.143  13.053 1.00 14.10 ?  146  LYS A HD2  1 
ATOM   2072  H HD3  . LYS A 1 180 ? -24.470 29.493  11.506 1.00 14.10 ?  146  LYS A HD3  1 
ATOM   2073  H HE2  . LYS A 1 180 ? -25.610 31.100  12.810 1.00 17.07 ?  146  LYS A HE2  1 
ATOM   2074  H HE3  . LYS A 1 180 ? -26.618 30.359  11.830 1.00 17.07 ?  146  LYS A HE3  1 
ATOM   2075  H HZ1  . LYS A 1 180 ? -27.414 30.518  13.979 1.00 17.45 ?  146  LYS A HZ1  1 
ATOM   2076  H HZ2  . LYS A 1 180 ? -27.349 29.137  13.546 1.00 17.45 ?  146  LYS A HZ2  1 
ATOM   2077  H HZ3  . LYS A 1 180 ? -26.345 29.662  14.449 1.00 17.45 ?  146  LYS A HZ3  1 
ATOM   2078  N N    . SER A 1 181 ? -25.053 24.612  8.764  1.00 9.71  ?  147  SER A N    1 
ATOM   2079  C CA   . SER A 1 181 ? -24.411 23.756  7.774  1.00 11.12 ?  147  SER A CA   1 
ATOM   2080  C C    . SER A 1 181 ? -22.938 24.093  7.592  1.00 8.49  ?  147  SER A C    1 
ATOM   2081  O O    . SER A 1 181 ? -22.110 23.181  7.506  1.00 9.68  ?  147  SER A O    1 
ATOM   2082  C CB   . SER A 1 181 ? -25.154 23.807  6.431  1.00 11.99 ?  147  SER A CB   1 
ATOM   2083  O OG   . SER A 1 181 ? -25.290 25.125  5.953  1.00 13.07 ?  147  SER A OG   1 
ATOM   2084  H H    . SER A 1 181 ? -25.749 25.029  8.480  1.00 11.65 ?  147  SER A H    1 
ATOM   2085  H HA   . SER A 1 181 ? -24.465 22.843  8.098  1.00 13.35 ?  147  SER A HA   1 
ATOM   2086  H HB2  . SER A 1 181 ? -24.655 23.290  5.779  1.00 14.39 ?  147  SER A HB2  1 
ATOM   2087  H HB3  . SER A 1 181 ? -26.038 23.427  6.550  1.00 14.39 ?  147  SER A HB3  1 
ATOM   2088  H HG   . SER A 1 181 ? -24.537 25.495  5.914  1.00 15.69 ?  147  SER A HG   1 
ATOM   2089  N N    . PHE A 1 182 ? -22.580 25.377  7.532  1.00 8.72  ?  148  PHE A N    1 
ATOM   2090  C CA   . PHE A 1 182 ? -21.187 25.699  7.232  1.00 7.44  ?  148  PHE A CA   1 
ATOM   2091  C C    . PHE A 1 182 ? -20.274 25.322  8.379  1.00 8.47  ?  148  PHE A C    1 
ATOM   2092  O O    . PHE A 1 182 ? -19.099 25.021  8.146  1.00 8.80  ?  148  PHE A O    1 
ATOM   2093  C CB   . PHE A 1 182 ? -21.001 27.156  6.798  1.00 9.12  ?  148  PHE A CB   1 
ATOM   2094  C CG   . PHE A 1 182 ? -20.853 28.164  7.918  1.00 9.62  ?  148  PHE A CG   1 
ATOM   2095  C CD1  . PHE A 1 182 ? -21.964 28.681  8.572  1.00 10.12 ?  148  PHE A CD1  1 
ATOM   2096  C CD2  . PHE A 1 182 ? -19.603 28.655  8.262  1.00 10.72 ?  148  PHE A CD2  1 
ATOM   2097  C CE1  . PHE A 1 182 ? -21.814 29.641  9.565  1.00 10.00 ?  148  PHE A CE1  1 
ATOM   2098  C CE2  . PHE A 1 182 ? -19.453 29.608  9.254  1.00 11.62 ?  148  PHE A CE2  1 
ATOM   2099  C CZ   . PHE A 1 182 ? -20.548 30.096  9.908  1.00 10.36 ?  148  PHE A CZ   1 
ATOM   2100  H H    . PHE A 1 182 ? -23.101 26.050  7.656  1.00 10.46 ?  148  PHE A H    1 
ATOM   2101  H HA   . PHE A 1 182 ? -20.921 25.177  6.459  1.00 8.93  ?  148  PHE A HA   1 
ATOM   2102  H HB2  . PHE A 1 182 ? -20.199 27.211  6.255  1.00 10.94 ?  148  PHE A HB2  1 
ATOM   2103  H HB3  . PHE A 1 182 ? -21.775 27.418  6.276  1.00 10.94 ?  148  PHE A HB3  1 
ATOM   2104  H HD1  . PHE A 1 182 ? -22.815 28.382  8.344  1.00 12.14 ?  148  PHE A HD1  1 
ATOM   2105  H HD2  . PHE A 1 182 ? -18.851 28.338  7.816  1.00 12.86 ?  148  PHE A HD2  1 
ATOM   2106  H HE1  . PHE A 1 182 ? -22.563 29.978  10.002 1.00 11.99 ?  148  PHE A HE1  1 
ATOM   2107  H HE2  . PHE A 1 182 ? -18.604 29.917  9.476  1.00 13.94 ?  148  PHE A HE2  1 
ATOM   2108  H HZ   . PHE A 1 182 ? -20.446 30.731  10.580 1.00 12.43 ?  148  PHE A HZ   1 
ATOM   2109  N N    . VAL A 1 183 ? -20.801 25.305  9.606  1.00 9.18  ?  149  VAL A N    1 
ATOM   2110  C CA   . VAL A 1 183 ? -20.021 24.860  10.755 1.00 9.53  ?  149  VAL A CA   1 
ATOM   2111  C C    . VAL A 1 183 ? -19.817 23.359  10.694 1.00 7.98  ?  149  VAL A C    1 
ATOM   2112  O O    . VAL A 1 183 ? -18.718 22.865  10.933 1.00 8.41  ?  149  VAL A O    1 
ATOM   2113  C CB   . VAL A 1 183 ? -20.705 25.283  12.061 1.00 7.32  ?  149  VAL A CB   1 
ATOM   2114  C CG1  . VAL A 1 183 ? -19.962 24.716  13.261 1.00 9.11  ?  149  VAL A CG1  1 
ATOM   2115  C CG2  . VAL A 1 183 ? -20.777 26.810  12.152 1.00 9.40  ?  149  VAL A CG2  1 
ATOM   2116  H H    . VAL A 1 183 ? -21.604 25.545  9.796  1.00 11.01 ?  149  VAL A H    1 
ATOM   2117  H HA   . VAL A 1 183 ? -19.149 25.284  10.724 1.00 11.43 ?  149  VAL A HA   1 
ATOM   2118  H HB   . VAL A 1 183 ? -21.609 24.932  12.069 1.00 8.78  ?  149  VAL A HB   1 
ATOM   2119  H HG11 . VAL A 1 183 ? -20.364 25.063  14.073 1.00 10.93 ?  149  VAL A HG11 1 
ATOM   2120  H HG12 . VAL A 1 183 ? -20.029 23.749  13.246 1.00 10.93 ?  149  VAL A HG12 1 
ATOM   2121  H HG13 . VAL A 1 183 ? -19.031 24.985  13.212 1.00 10.93 ?  149  VAL A HG13 1 
ATOM   2122  H HG21 . VAL A 1 183 ? -21.137 27.058  13.019 1.00 11.28 ?  149  VAL A HG21 1 
ATOM   2123  H HG22 . VAL A 1 183 ? -19.885 27.175  12.048 1.00 11.28 ?  149  VAL A HG22 1 
ATOM   2124  H HG23 . VAL A 1 183 ? -21.355 27.142  11.448 1.00 11.28 ?  149  VAL A HG23 1 
ATOM   2125  N N    . GLN A 1 184 ? -20.885 22.610  10.403 1.00 8.70  ?  150  GLN A N    1 
ATOM   2126  C CA   . GLN A 1 184 ? -20.739 21.171  10.224 1.00 8.40  ?  150  GLN A CA   1 
ATOM   2127  C C    . GLN A 1 184 ? -19.669 20.853  9.189  1.00 8.42  ?  150  GLN A C    1 
ATOM   2128  O O    . GLN A 1 184 ? -18.819 19.973  9.391  1.00 9.60  ?  150  GLN A O    1 
ATOM   2129  C CB   . GLN A 1 184 ? -22.064 20.556  9.769  1.00 8.73  ?  150  GLN A CB   1 
ATOM   2130  C CG   . GLN A 1 184 ? -23.159 20.659  10.789 1.00 9.16  ?  150  GLN A CG   1 
ATOM   2131  C CD   . GLN A 1 184 ? -24.506 20.233  10.242 1.00 9.75  ?  150  GLN A CD   1 
ATOM   2132  O OE1  . GLN A 1 184 ? -24.593 19.451  9.295  1.00 10.76 ?  150  GLN A OE1  1 
ATOM   2133  N NE2  . GLN A 1 184 ? -25.570 20.763  10.832 1.00 11.09 ?  150  GLN A NE2  1 
ATOM   2134  H H    . GLN A 1 184 ? -21.686 22.907  10.306 1.00 10.44 ?  150  GLN A H    1 
ATOM   2135  H HA   . GLN A 1 184 ? -20.487 20.785  11.078 1.00 10.08 ?  150  GLN A HA   1 
ATOM   2136  H HB2  . GLN A 1 184 ? -22.362 21.015  8.968  1.00 10.48 ?  150  GLN A HB2  1 
ATOM   2137  H HB3  . GLN A 1 184 ? -21.923 19.616  9.580  1.00 10.48 ?  150  GLN A HB3  1 
ATOM   2138  H HG2  . GLN A 1 184 ? -22.946 20.085  11.542 1.00 10.99 ?  150  GLN A HG2  1 
ATOM   2139  H HG3  . GLN A 1 184 ? -23.232 21.580  11.085 1.00 10.99 ?  150  GLN A HG3  1 
ATOM   2140  H HE21 . GLN A 1 184 ? -25.470 21.314  11.485 1.00 13.31 ?  150  GLN A HE21 1 
ATOM   2141  H HE22 . GLN A 1 184 ? -26.360 20.556  10.561 1.00 13.31 ?  150  GLN A HE22 1 
ATOM   2142  N N    . GLU A 1 185 ? -19.722 21.529  8.043  1.00 8.82  ?  151  GLU A N    1 
ATOM   2143  C CA   . GLU A 1 185 ? -18.779 21.223  6.970  1.00 8.25  ?  151  GLU A CA   1 
ATOM   2144  C C    . GLU A 1 185 ? -17.352 21.580  7.365  1.00 8.69  ?  151  GLU A C    1 
ATOM   2145  O O    . GLU A 1 185 ? -16.421 20.815  7.085  1.00 9.26  ?  151  GLU A O    1 
ATOM   2146  C CB   . GLU A 1 185 ? -19.207 21.912  5.665  1.00 9.52  ?  151  GLU A CB   1 
ATOM   2147  C CG   . GLU A 1 185 ? -20.551 21.410  5.141  1.00 9.96  ?  151  GLU A CG   1 
ATOM   2148  C CD   . GLU A 1 185 ? -20.609 19.908  4.878  1.00 10.72 ?  151  GLU A CD   1 
ATOM   2149  O OE1  . GLU A 1 185 ? -19.585 19.288  4.535  1.00 13.23 ?  151  GLU A OE1  1 
ATOM   2150  O OE2  . GLU A 1 185 ? -21.714 19.334  4.960  1.00 13.10 ?  151  GLU A OE2  1 
ATOM   2151  H H    . GLU A 1 185 ? -20.281 22.157  7.864  1.00 10.58 ?  151  GLU A H    1 
ATOM   2152  H HA   . GLU A 1 185 ? -18.797 20.268  6.798  1.00 9.89  ?  151  GLU A HA   1 
ATOM   2153  H HB2  . GLU A 1 185 ? -19.284 22.866  5.823  1.00 11.42 ?  151  GLU A HB2  1 
ATOM   2154  H HB3  . GLU A 1 185 ? -18.537 21.742  4.984  1.00 11.42 ?  151  GLU A HB3  1 
ATOM   2155  H HG2  . GLU A 1 185 ? -21.236 21.619  5.795  1.00 11.95 ?  151  GLU A HG2  1 
ATOM   2156  H HG3  . GLU A 1 185 ? -20.745 21.861  4.304  1.00 11.95 ?  151  GLU A HG3  1 
ATOM   2157  N N    . TYR A 1 186 ? -17.158 22.719  8.026  1.00 8.18  ?  152  TYR A N    1 
ATOM   2158  C CA   . TYR A 1 186 ? -15.826 23.076  8.498  1.00 8.13  ?  152  TYR A CA   1 
ATOM   2159  C C    . TYR A 1 186 ? -15.302 22.014  9.456  1.00 7.71  ?  152  TYR A C    1 
ATOM   2160  O O    . TYR A 1 186 ? -14.157 21.551  9.343  1.00 8.55  ?  152  TYR A O    1 
ATOM   2161  C CB   . TYR A 1 186 ? -15.843 24.435  9.214  1.00 9.44  ?  152  TYR A CB   1 
ATOM   2162  C CG   . TYR A 1 186 ? -14.507 24.678  9.876  1.00 8.99  ?  152  TYR A CG   1 
ATOM   2163  C CD1  . TYR A 1 186 ? -13.415 25.134  9.139  1.00 9.04  ?  152  TYR A CD1  1 
ATOM   2164  C CD2  . TYR A 1 186 ? -14.311 24.370  11.219 1.00 9.02  ?  152  TYR A CD2  1 
ATOM   2165  C CE1  . TYR A 1 186 ? -12.179 25.288  9.716  1.00 8.82  ?  152  TYR A CE1  1 
ATOM   2166  C CE2  . TYR A 1 186 ? -13.052 24.526  11.805 1.00 8.37  ?  152  TYR A CE2  1 
ATOM   2167  C CZ   . TYR A 1 186 ? -12.005 24.985  11.050 1.00 9.11  ?  152  TYR A CZ   1 
ATOM   2168  O OH   . TYR A 1 186 ? -10.742 25.114  11.587 1.00 9.26  ?  152  TYR A OH   1 
ATOM   2169  H H    . TYR A 1 186 ? -17.772 23.293  8.210  1.00 9.82  ?  152  TYR A H    1 
ATOM   2170  H HA   . TYR A 1 186 ? -15.242 23.145  7.727  1.00 9.76  ?  152  TYR A HA   1 
ATOM   2171  H HB2  . TYR A 1 186 ? -16.007 25.142  8.571  1.00 11.32 ?  152  TYR A HB2  1 
ATOM   2172  H HB3  . TYR A 1 186 ? -16.535 24.438  9.894  1.00 11.32 ?  152  TYR A HB3  1 
ATOM   2173  H HD1  . TYR A 1 186 ? -13.526 25.337  8.238  1.00 10.85 ?  152  TYR A HD1  1 
ATOM   2174  H HD2  . TYR A 1 186 ? -15.023 24.058  11.730 1.00 10.82 ?  152  TYR A HD2  1 
ATOM   2175  H HE1  . TYR A 1 186 ? -11.462 25.596  9.209  1.00 10.58 ?  152  TYR A HE1  1 
ATOM   2176  H HE2  . TYR A 1 186 ? -12.926 24.319  12.702 1.00 10.05 ?  152  TYR A HE2  1 
ATOM   2177  H HH   . TYR A 1 186 ? -10.708 24.732  12.334 1.00 11.11 ?  152  TYR A HH   1 
ATOM   2178  N N    . TRP A 1 187 ? -16.128 21.622  10.423 1.00 8.33  ?  153  TRP A N    1 
ATOM   2179  C CA   . TRP A 1 187 ? -15.667 20.717  11.467 1.00 7.46  ?  153  TRP A CA   1 
ATOM   2180  C C    . TRP A 1 187 ? -15.363 19.349  10.887 1.00 8.87  ?  153  TRP A C    1 
ATOM   2181  O O    . TRP A 1 187 ? -14.304 18.771  11.152 1.00 8.04  ?  153  TRP A O    1 
ATOM   2182  C CB   . TRP A 1 187 ? -16.735 20.636  12.560 1.00 8.22  ?  153  TRP A CB   1 
ATOM   2183  C CG   . TRP A 1 187 ? -16.320 19.889  13.809 1.00 7.13  ?  153  TRP A CG   1 
ATOM   2184  C CD1  . TRP A 1 187 ? -15.805 20.422  14.964 1.00 8.10  ?  153  TRP A CD1  1 
ATOM   2185  C CD2  . TRP A 1 187 ? -16.409 18.473  14.022 1.00 6.96  ?  153  TRP A CD2  1 
ATOM   2186  N NE1  . TRP A 1 187 ? -15.569 19.420  15.867 1.00 7.72  ?  153  TRP A NE1  1 
ATOM   2187  C CE2  . TRP A 1 187 ? -15.929 18.217  15.324 1.00 7.71  ?  153  TRP A CE2  1 
ATOM   2188  C CE3  . TRP A 1 187 ? -16.863 17.395  13.245 1.00 8.10  ?  153  TRP A CE3  1 
ATOM   2189  C CZ2  . TRP A 1 187 ? -15.882 16.932  15.864 1.00 7.33  ?  153  TRP A CZ2  1 
ATOM   2190  C CZ3  . TRP A 1 187 ? -16.815 16.121  13.785 1.00 9.03  ?  153  TRP A CZ3  1 
ATOM   2191  C CH2  . TRP A 1 187 ? -16.338 15.903  15.085 1.00 8.25  ?  153  TRP A CH2  1 
ATOM   2192  H H    . TRP A 1 187 ? -16.950 21.863  10.496 1.00 10.00 ?  153  TRP A H    1 
ATOM   2193  H HA   . TRP A 1 187 ? -14.851 21.055  11.868 1.00 8.95  ?  153  TRP A HA   1 
ATOM   2194  H HB2  . TRP A 1 187 ? -16.971 21.538  12.826 1.00 9.86  ?  153  TRP A HB2  1 
ATOM   2195  H HB3  . TRP A 1 187 ? -17.512 20.183  12.196 1.00 9.86  ?  153  TRP A HB3  1 
ATOM   2196  H HD1  . TRP A 1 187 ? -15.641 21.326  15.110 1.00 9.72  ?  153  TRP A HD1  1 
ATOM   2197  H HE1  . TRP A 1 187 ? -15.244 19.530  16.656 1.00 9.26  ?  153  TRP A HE1  1 
ATOM   2198  H HE3  . TRP A 1 187 ? -17.189 17.535  12.385 1.00 9.72  ?  153  TRP A HE3  1 
ATOM   2199  H HZ2  . TRP A 1 187 ? -15.552 16.780  16.720 1.00 8.80  ?  153  TRP A HZ2  1 
ATOM   2200  H HZ3  . TRP A 1 187 ? -17.104 15.398  13.276 1.00 10.84 ?  153  TRP A HZ3  1 
ATOM   2201  H HH2  . TRP A 1 187 ? -16.332 15.038  15.427 1.00 9.90  ?  153  TRP A HH2  1 
ATOM   2202  N N    . LEU A 1 188 ? -16.272 18.817  10.063 1.00 8.48  ?  154  LEU A N    1 
ATOM   2203  C CA   . LEU A 1 188 ? -16.047 17.507  9.466  1.00 9.08  ?  154  LEU A CA   1 
ATOM   2204  C C    . LEU A 1 188 ? -14.786 17.498  8.615  1.00 8.37  ?  154  LEU A C    1 
ATOM   2205  O O    . LEU A 1 188 ? -13.986 16.562  8.703  1.00 8.82  ?  154  LEU A O    1 
ATOM   2206  C CB   . LEU A 1 188 ? -17.262 17.090  8.636  1.00 9.51  ?  154  LEU A CB   1 
ATOM   2207  C CG   . LEU A 1 188 ? -18.503 16.713  9.442  1.00 10.24 ?  154  LEU A CG   1 
ATOM   2208  C CD1  . LEU A 1 188 ? -19.737 16.633  8.529  1.00 10.16 ?  154  LEU A CD1  1 
ATOM   2209  C CD2  . LEU A 1 188 ? -18.305 15.404  10.169 1.00 9.80  ?  154  LEU A CD2  1 
ATOM   2210  H H    . LEU A 1 188 ? -17.013 19.191  9.839  1.00 10.18 ?  154  LEU A H    1 
ATOM   2211  H HA   . LEU A 1 188 ? -15.935 16.857  10.177 1.00 10.90 ?  154  LEU A HA   1 
ATOM   2212  H HB2  . LEU A 1 188 ? -17.504 17.829  8.057  1.00 11.42 ?  154  LEU A HB2  1 
ATOM   2213  H HB3  . LEU A 1 188 ? -17.016 16.317  8.103  1.00 11.42 ?  154  LEU A HB3  1 
ATOM   2214  H HG   . LEU A 1 188 ? -18.656 17.403  10.106 1.00 12.29 ?  154  LEU A HG   1 
ATOM   2215  H HD11 . LEU A 1 188 ? -20.170 15.775  8.658  1.00 12.19 ?  154  LEU A HD11 1 
ATOM   2216  H HD12 . LEU A 1 188 ? -20.348 17.350  8.761  1.00 12.19 ?  154  LEU A HD12 1 
ATOM   2217  H HD13 . LEU A 1 188 ? -19.454 16.726  7.606  1.00 12.19 ?  154  LEU A HD13 1 
ATOM   2218  H HD21 . LEU A 1 188 ? -19.087 15.223  10.713 1.00 11.75 ?  154  LEU A HD21 1 
ATOM   2219  H HD22 . LEU A 1 188 ? -18.184 14.696  9.517  1.00 11.75 ?  154  LEU A HD22 1 
ATOM   2220  H HD23 . LEU A 1 188 ? -17.519 15.471  10.733 1.00 11.75 ?  154  LEU A HD23 1 
ATOM   2221  N N    . LYS A 1 189 ? -14.591 18.527  7.797  1.00 7.98  ?  155  LYS A N    1 
ATOM   2222  C CA   . LYS A 1 189 ? -13.394 18.594  6.974  1.00 8.77  ?  155  LYS A CA   1 
ATOM   2223  C C    . LYS A 1 189 ? -12.138 18.677  7.834  1.00 10.51 ?  155  LYS A C    1 
ATOM   2224  O O    . LYS A 1 189 ? -11.113 18.077  7.493  1.00 9.49  ?  155  LYS A O    1 
ATOM   2225  C CB   . LYS A 1 189 ? -13.494 19.765  5.995  1.00 10.40 ?  155  LYS A CB   1 
ATOM   2226  C CG   . LYS A 1 189 ? -12.224 20.042  5.208  1.00 13.03 ?  155  LYS A CG   1 
ATOM   2227  C CD   . LYS A 1 189 ? -12.455 21.124  4.152  1.00 14.27 ?  155  LYS A CD   1 
ATOM   2228  C CE   . LYS A 1 189 ? -11.162 21.747  3.698  1.00 18.88 ?  155  LYS A CE   1 
ATOM   2229  N NZ   . LYS A 1 189 ? -10.331 20.746  3.001  1.00 20.60 ?  155  LYS A NZ   1 
ATOM   2230  H H    . LYS A 1 189 ? -15.130 19.191  7.702  1.00 9.58  ?  155  LYS A H    1 
ATOM   2231  H HA   . LYS A 1 189 ? -13.325 17.785  6.443  1.00 10.53 ?  155  LYS A HA   1 
ATOM   2232  H HB2  . LYS A 1 189 ? -14.199 19.574  5.356  1.00 12.48 ?  155  LYS A HB2  1 
ATOM   2233  H HB3  . LYS A 1 189 ? -13.709 20.568  6.495  1.00 12.48 ?  155  LYS A HB3  1 
ATOM   2234  H HG2  . LYS A 1 189 ? -11.529 20.346  5.812  1.00 15.63 ?  155  LYS A HG2  1 
ATOM   2235  H HG3  . LYS A 1 189 ? -11.939 19.230  4.758  1.00 15.63 ?  155  LYS A HG3  1 
ATOM   2236  H HD2  . LYS A 1 189 ? -12.890 20.730  3.380  1.00 17.12 ?  155  LYS A HD2  1 
ATOM   2237  H HD3  . LYS A 1 189 ? -13.014 21.822  4.528  1.00 17.12 ?  155  LYS A HD3  1 
ATOM   2238  H HE2  . LYS A 1 189 ? -11.349 22.476  3.086  1.00 22.66 ?  155  LYS A HE2  1 
ATOM   2239  H HE3  . LYS A 1 189 ? -10.672 22.077  4.467  1.00 22.66 ?  155  LYS A HE3  1 
ATOM   2240  H HZ1  . LYS A 1 189 ? -10.092 20.102  3.566  1.00 24.72 ?  155  LYS A HZ1  1 
ATOM   2241  H HZ2  . LYS A 1 189 ? -10.790 20.384  2.329  1.00 24.72 ?  155  LYS A HZ2  1 
ATOM   2242  H HZ3  . LYS A 1 189 ? -9.599  21.132  2.675  1.00 24.72 ?  155  LYS A HZ3  1 
ATOM   2243  N N    . SER A 1 190 ? -12.187 19.400  8.959  1.00 8.07  ?  156  SER A N    1 
ATOM   2244  C CA   . SER A 1 190 ? -10.994 19.501  9.792  1.00 7.64  ?  156  SER A CA   1 
ATOM   2245  C C    . SER A 1 190 ? -10.590 18.129  10.322 1.00 8.48  ?  156  SER A C    1 
ATOM   2246  O O    . SER A 1 190 ? -9.402  17.803  10.367 1.00 8.86  ?  156  SER A O    1 
ATOM   2247  C CB   . SER A 1 190 ? -11.201 20.519  10.918 1.00 9.00  ?  156  SER A CB   1 
ATOM   2248  O OG   . SER A 1 190 ? -12.034 20.021  11.961 1.00 8.68  ?  156  SER A OG   1 
ATOM   2249  H H    . SER A 1 190 ? -12.876 19.825  9.249  1.00 9.68  ?  156  SER A H    1 
ATOM   2250  H HA   . SER A 1 190 ? -10.257 19.836  9.258  1.00 9.17  ?  156  SER A HA   1 
ATOM   2251  H HB2  . SER A 1 190 ? -10.335 20.743  11.295 1.00 10.80 ?  156  SER A HB2  1 
ATOM   2252  H HB3  . SER A 1 190 ? -11.615 21.313  10.545 1.00 10.80 ?  156  SER A HB3  1 
ATOM   2253  H HG   . SER A 1 190 ? -12.793 19.830  11.656 1.00 10.41 ?  156  SER A HG   1 
ATOM   2254  N N    . VAL A 1 191 ? -11.564 17.295  10.691 1.00 7.54  ?  157  VAL A N    1 
ATOM   2255  C CA   . VAL A 1 191 ? -11.256 15.964  11.200 1.00 8.38  ?  157  VAL A CA   1 
ATOM   2256  C C    . VAL A 1 191 ? -10.764 15.076  10.072 1.00 8.95  ?  157  VAL A C    1 
ATOM   2257  O O    . VAL A 1 191 ? -9.726  14.415  10.183 1.00 9.02  ?  157  VAL A O    1 
ATOM   2258  C CB   . VAL A 1 191 ? -12.493 15.365  11.894 1.00 8.25  ?  157  VAL A CB   1 
ATOM   2259  C CG1  . VAL A 1 191 ? -12.242 13.903  12.271 1.00 8.68  ?  157  VAL A CG1  1 
ATOM   2260  C CG2  . VAL A 1 191 ? -12.854 16.158  13.147 1.00 8.32  ?  157  VAL A CG2  1 
ATOM   2261  H H    . VAL A 1 191 ? -12.404 17.477  10.656 1.00 9.05  ?  157  VAL A H    1 
ATOM   2262  H HA   . VAL A 1 191 ? -10.546 16.034  11.857 1.00 10.05 ?  157  VAL A HA   1 
ATOM   2263  H HB   . VAL A 1 191 ? -13.238 15.409  11.274 1.00 9.90  ?  157  VAL A HB   1 
ATOM   2264  H HG11 . VAL A 1 191 ? -13.005 13.569  12.768 1.00 10.42 ?  157  VAL A HG11 1 
ATOM   2265  H HG12 . VAL A 1 191 ? -12.122 13.384  11.461 1.00 10.42 ?  157  VAL A HG12 1 
ATOM   2266  H HG13 . VAL A 1 191 ? -11.443 13.851  12.818 1.00 10.42 ?  157  VAL A HG13 1 
ATOM   2267  H HG21 . VAL A 1 191 ? -13.688 15.817  13.507 1.00 9.99  ?  157  VAL A HG21 1 
ATOM   2268  H HG22 . VAL A 1 191 ? -12.145 16.055  13.801 1.00 9.99  ?  157  VAL A HG22 1 
ATOM   2269  H HG23 . VAL A 1 191 ? -12.953 17.094  12.911 1.00 9.99  ?  157  VAL A HG23 1 
ATOM   2270  N N    . GLU A 1 192 ? -11.506 15.050  8.961  1.00 7.84  ?  158  GLU A N    1 
ATOM   2271  C CA   . GLU A 1 192 ? -11.146 14.183  7.838  1.00 9.17  ?  158  GLU A CA   1 
ATOM   2272  C C    . GLU A 1 192 ? -9.767  14.528  7.300  1.00 8.91  ?  158  GLU A C    1 
ATOM   2273  O O    . GLU A 1 192 ? -8.974  13.632  6.989  1.00 9.76  ?  158  GLU A O    1 
ATOM   2274  C CB   . GLU A 1 192 ? -12.223 14.285  6.752  1.00 9.78  ?  158  GLU A CB   1 
ATOM   2275  C CG   . GLU A 1 192 ? -13.563 13.696  7.218  1.00 11.04 ?  158  GLU A CG   1 
ATOM   2276  C CD   . GLU A 1 192 ? -14.761 14.001  6.337  1.00 12.10 ?  158  GLU A CD   1 
ATOM   2277  O OE1  . GLU A 1 192 ? -14.637 14.837  5.415  1.00 15.26 ?  158  GLU A OE1  1 
ATOM   2278  O OE2  . GLU A 1 192 ? -15.821 13.383  6.598  1.00 13.33 ?  158  GLU A OE2  1 
ATOM   2279  H H    . GLU A 1 192 ? -12.215 15.519  8.833  1.00 9.41  ?  158  GLU A H    1 
ATOM   2280  H HA   . GLU A 1 192 ? -11.114 13.259  8.133  1.00 11.01 ?  158  GLU A HA   1 
ATOM   2281  H HB2  . GLU A 1 192 ? -12.362 15.219  6.528  1.00 11.74 ?  158  GLU A HB2  1 
ATOM   2282  H HB3  . GLU A 1 192 ? -11.931 13.796  5.967  1.00 11.74 ?  158  GLU A HB3  1 
ATOM   2283  H HG2  . GLU A 1 192 ? -13.474 12.731  7.256  1.00 13.25 ?  158  GLU A HG2  1 
ATOM   2284  H HG3  . GLU A 1 192 ? -13.760 14.047  8.100  1.00 13.25 ?  158  GLU A HG3  1 
ATOM   2285  N N    . ASP A 1 193 ? -9.458  15.811  7.187  1.00 9.09  ?  159  ASP A N    1 
ATOM   2286  C CA   . ASP A 1 193 ? -8.170  16.197  6.625  1.00 8.90  ?  159  ASP A CA   1 
ATOM   2287  C C    . ASP A 1 193 ? -7.037  15.758  7.547  1.00 9.55  ?  159  ASP A C    1 
ATOM   2288  O O    . ASP A 1 193 ? -5.979  15.317  7.081  1.00 10.43 ?  159  ASP A O    1 
ATOM   2289  C CB   . ASP A 1 193 ? -8.098  17.714  6.405  1.00 9.86  ?  159  ASP A CB   1 
ATOM   2290  C CG   . ASP A 1 193 ? -8.871  18.201  5.187  1.00 11.48 ?  159  ASP A CG   1 
ATOM   2291  O OD1  . ASP A 1 193 ? -9.368  17.375  4.422  1.00 15.18 ?  159  ASP A OD1  1 
ATOM   2292  O OD2  . ASP A 1 193 ? -8.957  19.441  5.041  1.00 13.38 ?  159  ASP A OD2  1 
ATOM   2293  H H    . ASP A 1 193 ? -9.964  16.465  7.422  1.00 10.91 ?  159  ASP A H    1 
ATOM   2294  H HA   . ASP A 1 193 ? -8.072  15.769  5.760  1.00 10.69 ?  159  ASP A HA   1 
ATOM   2295  H HB2  . ASP A 1 193 ? -8.466  18.159  7.184  1.00 11.83 ?  159  ASP A HB2  1 
ATOM   2296  H HB3  . ASP A 1 193 ? -7.170  17.967  6.285  1.00 11.83 ?  159  ASP A HB3  1 
ATOM   2297  N N    . MET A 1 194 ? -7.212  15.881  8.866  1.00 9.02  ?  160  MET A N    1 
ATOM   2298  C CA   . MET A 1 194 ? -6.133  15.470  9.757  1.00 8.56  ?  160  MET A CA   1 
ATOM   2299  C C    . MET A 1 194 ? -5.977  13.950  9.767  1.00 10.41 ?  160  MET A C    1 
ATOM   2300  O O    . MET A 1 194 ? -4.858  13.421  9.725  1.00 9.54  ?  160  MET A O    1 
ATOM   2301  C CB   . MET A 1 194 ? -6.376  16.006  11.170 1.00 8.68  ?  160  MET A CB   1 
ATOM   2302  C CG   . MET A 1 194 ? -5.281  15.606  12.138 1.00 8.41  ?  160  MET A CG   1 
ATOM   2303  S SD   . MET A 1 194 ? -3.654  16.330  11.823 1.00 10.34 ?  160  MET A SD   1 
ATOM   2304  C CE   . MET A 1 194 ? -3.877  17.981  12.480 1.00 11.17 ?  160  MET A CE   1 
ATOM   2305  H H    . MET A 1 194 ? -7.918  16.188  9.251  1.00 10.82 ?  160  MET A H    1 
ATOM   2306  H HA   . MET A 1 194 ? -5.305  15.864  9.441  1.00 10.27 ?  160  MET A HA   1 
ATOM   2307  H HB2  . MET A 1 194 ? -6.413  16.975  11.140 1.00 10.42 ?  160  MET A HB2  1 
ATOM   2308  H HB3  . MET A 1 194 ? -7.216  15.652  11.503 1.00 10.42 ?  160  MET A HB3  1 
ATOM   2309  H HG2  . MET A 1 194 ? -5.548  15.877  13.030 1.00 10.09 ?  160  MET A HG2  1 
ATOM   2310  H HG3  . MET A 1 194 ? -5.178  14.642  12.101 1.00 10.09 ?  160  MET A HG3  1 
ATOM   2311  H HE1  . MET A 1 194 ? -3.028  18.449  12.452 1.00 13.40 ?  160  MET A HE1  1 
ATOM   2312  H HE2  . MET A 1 194 ? -4.531  18.450  11.939 1.00 13.40 ?  160  MET A HE2  1 
ATOM   2313  H HE3  . MET A 1 194 ? -4.190  17.917  13.396 1.00 13.40 ?  160  MET A HE3  1 
ATOM   2314  N N    . VAL A 1 195 ? -7.086  13.220  9.806  1.00 8.38  ?  161  VAL A N    1 
ATOM   2315  C CA   . VAL A 1 195 ? -6.992  11.769  9.820  1.00 8.73  ?  161  VAL A CA   1 
ATOM   2316  C C    . VAL A 1 195 ? -6.401  11.245  8.513  1.00 9.73  ?  161  VAL A C    1 
ATOM   2317  O O    . VAL A 1 195 ? -5.758  10.181  8.504  1.00 9.49  ?  161  VAL A O    1 
ATOM   2318  C CB   . VAL A 1 195 ? -8.355  11.139  10.165 1.00 8.96  ?  161  VAL A CB   1 
ATOM   2319  C CG1  . VAL A 1 195 ? -8.311  9.639   10.047 1.00 9.67  ?  161  VAL A CG1  1 
ATOM   2320  C CG2  . VAL A 1 195 ? -8.780  11.544  11.577 1.00 9.80  ?  161  VAL A CG2  1 
ATOM   2321  H H    . VAL A 1 195 ? -7.887  13.534  9.824  1.00 10.06 ?  161  VAL A H    1 
ATOM   2322  H HA   . VAL A 1 195 ? -6.379  11.507  10.525 1.00 10.47 ?  161  VAL A HA   1 
ATOM   2323  H HB   . VAL A 1 195 ? -9.012  11.466  9.530  1.00 10.75 ?  161  VAL A HB   1 
ATOM   2324  H HG11 . VAL A 1 195 ? -9.117  9.267   10.438 1.00 11.61 ?  161  VAL A HG11 1 
ATOM   2325  H HG12 . VAL A 1 195 ? -8.257  9.397   9.109  1.00 11.61 ?  161  VAL A HG12 1 
ATOM   2326  H HG13 . VAL A 1 195 ? -7.531  9.308   10.519 1.00 11.61 ?  161  VAL A HG13 1 
ATOM   2327  H HG21 . VAL A 1 195 ? -9.594  11.072  11.810 1.00 11.76 ?  161  VAL A HG21 1 
ATOM   2328  H HG22 . VAL A 1 195 ? -8.073  11.310  12.199 1.00 11.76 ?  161  VAL A HG22 1 
ATOM   2329  H HG23 . VAL A 1 195 ? -8.934  12.501  11.598 1.00 11.76 ?  161  VAL A HG23 1 
ATOM   2330  N N    . ALA A 1 196 ? -6.589  11.958  7.403  1.00 10.22 ?  162  ALA A N    1 
ATOM   2331  C CA   . ALA A 1 196 ? -6.054  11.484  6.128  1.00 9.57  ?  162  ALA A CA   1 
ATOM   2332  C C    . ALA A 1 196 ? -4.533  11.541  6.055  1.00 12.01 ?  162  ALA A C    1 
ATOM   2333  O O    . ALA A 1 196 ? -3.949  10.908  5.159  1.00 12.19 ?  162  ALA A O    1 
ATOM   2334  C CB   . ALA A 1 196 ? -6.634  12.281  4.966  1.00 11.12 ?  162  ALA A CB   1 
ATOM   2335  H H    . ALA A 1 196 ? -7.014  12.705  7.362  1.00 12.26 ?  162  ALA A H    1 
ATOM   2336  H HA   . ALA A 1 196 ? -6.328  10.559  6.031  1.00 11.49 ?  162  ALA A HA   1 
ATOM   2337  H HB1  . ALA A 1 196 ? -6.282  11.927  4.134  1.00 13.34 ?  162  ALA A HB1  1 
ATOM   2338  H HB2  . ALA A 1 196 ? -7.600  12.200  4.978  1.00 13.34 ?  162  ALA A HB2  1 
ATOM   2339  H HB3  . ALA A 1 196 ? -6.378  13.212  5.064  1.00 13.34 ?  162  ALA A HB3  1 
ATOM   2340  N N    . THR A 1 197 ? -3.878  12.266  6.958  1.00 9.28  ?  163  THR A N    1 
ATOM   2341  C CA   . THR A 1 197 ? -2.419  12.374  6.928  1.00 10.72 ?  163  THR A CA   1 
ATOM   2342  C C    . THR A 1 197 ? -1.785  11.043  7.345  1.00 10.94 ?  163  THR A C    1 
ATOM   2343  O O    . THR A 1 197 ? -2.439  10.188  7.936  1.00 11.09 ?  163  THR A O    1 
ATOM   2344  C CB   . THR A 1 197 ? -1.919  13.553  7.773  1.00 9.42  ?  163  THR A CB   1 
ATOM   2345  O OG1  . THR A 1 197 ? -2.159  13.317  9.175  1.00 10.79 ?  163  THR A OG1  1 
ATOM   2346  C CG2  . THR A 1 197 ? -2.574  14.857  7.333  1.00 10.71 ?  163  THR A CG2  1 
ATOM   2347  H H    . THR A 1 197 ? -4.252  12.703  7.597  1.00 11.14 ?  163  THR A H    1 
ATOM   2348  H HA   . THR A 1 197 ? -2.122  12.563  6.024  1.00 12.87 ?  163  THR A HA   1 
ATOM   2349  H HB   . THR A 1 197 ? -0.962  13.646  7.644  1.00 11.31 ?  163  THR A HB   1 
ATOM   2350  H HG1  . THR A 1 197 ? -2.968  13.128  9.300  1.00 12.95 ?  163  THR A HG1  1 
ATOM   2351  H HG21 . THR A 1 197 ? -2.244  15.593  7.872  1.00 12.86 ?  163  THR A HG21 1 
ATOM   2352  H HG22 . THR A 1 197 ? -2.369  15.033  6.401  1.00 12.86 ?  163  THR A HG22 1 
ATOM   2353  H HG23 . THR A 1 197 ? -3.537  14.797  7.437  1.00 12.86 ?  163  THR A HG23 1 
ATOM   2354  N N    . PRO A 1 198 ? -0.518  10.816  6.992  1.00 11.56 ?  164  PRO A N    1 
ATOM   2355  C CA   . PRO A 1 198 ? 0.006   9.440   7.038  1.00 11.68 ?  164  PRO A CA   1 
ATOM   2356  C C    . PRO A 1 198 ? 0.193   8.875   8.429  1.00 10.88 ?  164  PRO A C    1 
ATOM   2357  O O    . PRO A 1 198 ? 0.158   7.650   8.593  1.00 15.27 ?  164  PRO A O    1 
ATOM   2358  C CB   . PRO A 1 198 ? 1.332   9.519   6.263  1.00 15.54 ?  164  PRO A CB   1 
ATOM   2359  C CG   . PRO A 1 198 ? 1.623   10.927  6.085  1.00 19.42 ?  164  PRO A CG   1 
ATOM   2360  C CD   . PRO A 1 198 ? 0.360   11.726  6.249  1.00 13.26 ?  164  PRO A CD   1 
ATOM   2361  H HA   . PRO A 1 198 ? -0.600  8.857   6.555  1.00 14.02 ?  164  PRO A HA   1 
ATOM   2362  H HB2  . PRO A 1 198 ? 2.033   9.087   6.776  1.00 18.64 ?  164  PRO A HB2  1 
ATOM   2363  H HB3  . PRO A 1 198 ? 1.231   9.079   5.404  1.00 18.64 ?  164  PRO A HB3  1 
ATOM   2364  H HG2  . PRO A 1 198 ? 2.274   11.198  6.751  1.00 23.30 ?  164  PRO A HG2  1 
ATOM   2365  H HG3  . PRO A 1 198 ? 1.984   11.061  5.195  1.00 23.30 ?  164  PRO A HG3  1 
ATOM   2366  H HD2  . PRO A 1 198 ? 0.527   12.535  6.757  1.00 15.91 ?  164  PRO A HD2  1 
ATOM   2367  H HD3  . PRO A 1 198 ? -0.023  11.948  5.386  1.00 15.91 ?  164  PRO A HD3  1 
ATOM   2368  N N    . ASN A 1 199 ? 0.366   9.703   9.443  1.00 10.32 ?  165  ASN A N    1 
ATOM   2369  C CA   . ASN A 1 199 ? 0.747   9.216   10.758 1.00 10.97 ?  165  ASN A CA   1 
ATOM   2370  C C    . ASN A 1 199 ? -0.386  9.275   11.766 1.00 10.73 ?  165  ASN A C    1 
ATOM   2371  O O    . ASN A 1 199 ? -0.155  9.021   12.949 1.00 10.82 ?  165  ASN A O    1 
ATOM   2372  C CB   . ASN A 1 199 ? 1.968   9.989   11.244 1.00 10.29 ?  165  ASN A CB   1 
ATOM   2373  C CG   . ASN A 1 199 ? 3.132   9.855   10.288 1.00 10.92 ?  165  ASN A CG   1 
ATOM   2374  O OD1  . ASN A 1 199 ? 3.562   8.735   10.009 1.00 14.47 ?  165  ASN A OD1  1 
ATOM   2375  N ND2  . ASN A 1 199 ? 3.604   10.958  9.746  1.00 11.31 ?  165  ASN A ND2  1 
ATOM   2376  H H    . ASN A 1 199 ? 0.269   10.556  9.395  1.00 12.39 ?  165  ASN A H    1 
ATOM   2377  H HA   . ASN A 1 199 ? 0.995   8.280   10.694 1.00 13.16 ?  165  ASN A HA   1 
ATOM   2378  H HB2  . ASN A 1 199 ? 1.742   10.930  11.318 1.00 12.35 ?  165  ASN A HB2  1 
ATOM   2379  H HB3  . ASN A 1 199 ? 2.242   9.645   12.108 1.00 12.35 ?  165  ASN A HB3  1 
ATOM   2380  H HD21 . ASN A 1 199 ? 4.265   10.918  9.198  1.00 13.57 ?  165  ASN A HD21 1 
ATOM   2381  H HD22 . ASN A 1 199 ? 3.250   11.717  9.939  1.00 13.57 ?  165  ASN A HD22 1 
ATOM   2382  N N    . ILE A 1 200 ? -1.592  9.612   11.330 1.00 9.14  ?  166  ILE A N    1 
ATOM   2383  C CA   . ILE A 1 200 ? -2.785  9.650   12.173 1.00 9.33  ?  166  ILE A CA   1 
ATOM   2384  C C    . ILE A 1 200 ? -3.708  8.520   11.746 1.00 8.74  ?  166  ILE A C    1 
ATOM   2385  O O    . ILE A 1 200 ? -4.015  8.366   10.557 1.00 8.35  ?  166  ILE A O    1 
ATOM   2386  C CB   . ILE A 1 200 ? -3.496  11.009  12.065 1.00 8.92  ?  166  ILE A CB   1 
ATOM   2387  C CG1  . ILE A 1 200 ? -2.585  12.152  12.495 1.00 10.65 ?  166  ILE A CG1  1 
ATOM   2388  C CG2  . ILE A 1 200 ? -4.810  10.989  12.852 1.00 8.84  ?  166  ILE A CG2  1 
ATOM   2389  C CD1  . ILE A 1 200 ? -2.270  12.174  13.954 1.00 13.76 ?  166  ILE A CD1  1 
ATOM   2390  H H    . ILE A 1 200 ? -1.754  9.832   10.515 1.00 10.97 ?  166  ILE A H    1 
ATOM   2391  H HA   . ILE A 1 200 ? -2.534  9.505   13.099 1.00 11.19 ?  166  ILE A HA   1 
ATOM   2392  H HB   . ILE A 1 200 ? -3.711  11.165  11.132 1.00 10.70 ?  166  ILE A HB   1 
ATOM   2393  H HG12 . ILE A 1 200 ? -1.746  12.076  12.015 1.00 12.78 ?  166  ILE A HG12 1 
ATOM   2394  H HG13 . ILE A 1 200 ? -3.018  12.992  12.276 1.00 12.78 ?  166  ILE A HG13 1 
ATOM   2395  H HG21 . ILE A 1 200 ? -5.195  11.880  12.847 1.00 10.61 ?  166  ILE A HG21 1 
ATOM   2396  H HG22 . ILE A 1 200 ? -5.420  10.363  12.433 1.00 10.61 ?  166  ILE A HG22 1 
ATOM   2397  H HG23 . ILE A 1 200 ? -4.627  10.713  13.764 1.00 10.61 ?  166  ILE A HG23 1 
ATOM   2398  H HD11 . ILE A 1 200 ? -1.654  12.902  14.133 1.00 16.51 ?  166  ILE A HD11 1 
ATOM   2399  H HD12 . ILE A 1 200 ? -3.091  12.306  14.453 1.00 16.51 ?  166  ILE A HD12 1 
ATOM   2400  H HD13 . ILE A 1 200 ? -1.864  11.329  14.203 1.00 16.51 ?  166  ILE A HD13 1 
ATOM   2401  N N    . ASP A 1 201 ? -4.164  7.737   12.717 1.00 8.61  ?  167  ASP A N    1 
ATOM   2402  C CA   . ASP A 1 201 ? -4.982  6.568   12.430 1.00 8.69  ?  167  ASP A CA   1 
ATOM   2403  C C    . ASP A 1 201 ? -6.460  6.782   12.675 1.00 8.34  ?  167  ASP A C    1 
ATOM   2404  O O    . ASP A 1 201 ? -7.266  5.954   12.245 1.00 9.15  ?  167  ASP A O    1 
ATOM   2405  C CB   . ASP A 1 201 ? -4.502  5.388   13.259 1.00 9.03  ?  167  ASP A CB   1 
ATOM   2406  C CG   . ASP A 1 201 ? -3.078  5.051   12.949 1.00 9.80  ?  167  ASP A CG   1 
ATOM   2407  O OD1  . ASP A 1 201 ? -2.807  4.687   11.767 1.00 11.52 ?  167  ASP A OD1  1 
ATOM   2408  O OD2  . ASP A 1 201 ? -2.229  5.179   13.828 1.00 10.20 ?  167  ASP A OD2  1 
ATOM   2409  H H    . ASP A 1 201 ? -4.011  7.864   13.554 1.00 10.34 ?  167  ASP A H    1 
ATOM   2410  H HA   . ASP A 1 201 ? -4.877  6.345   11.491 1.00 10.43 ?  167  ASP A HA   1 
ATOM   2411  H HB2  . ASP A 1 201 ? -4.567  5.609   14.201 1.00 10.84 ?  167  ASP A HB2  1 
ATOM   2412  H HB3  . ASP A 1 201 ? -5.050  4.612   13.061 1.00 10.84 ?  167  ASP A HB3  1 
ATOM   2413  N N    . GLY A 1 202 ? -6.834  7.851   13.365 1.00 7.95  ?  168  GLY A N    1 
ATOM   2414  C CA   . GLY A 1 202 ? -8.229  8.040   13.695 1.00 7.45  ?  168  GLY A CA   1 
ATOM   2415  C C    . GLY A 1 202 ? -8.397  9.259   14.559 1.00 7.53  ?  168  GLY A C    1 
ATOM   2416  O O    . GLY A 1 202 ? -7.506  10.099  14.664 1.00 8.50  ?  168  GLY A O    1 
ATOM   2417  H H    . GLY A 1 202 ? -6.307  8.469   13.646 1.00 9.54  ?  168  GLY A H    1 
ATOM   2418  H HA2  . GLY A 1 202 ? -8.747  8.155   12.883 1.00 8.94  ?  168  GLY A HA2  1 
ATOM   2419  H HA3  . GLY A 1 202 ? -8.562  7.265   14.175 1.00 8.94  ?  168  GLY A HA3  1 
ATOM   2420  N N    . THR A 1 203 ? -9.577  9.344   15.159 1.00 7.05  ?  169  THR A N    1 
ATOM   2421  C CA   . THR A 1 203 ? -9.955  10.514  15.934 1.00 7.09  ?  169  THR A CA   1 
ATOM   2422  C C    . THR A 1 203 ? -10.618 10.063  17.221 1.00 7.22  ?  169  THR A C    1 
ATOM   2423  O O    . THR A 1 203 ? -11.240 9.002   17.286 1.00 8.18  ?  169  THR A O    1 
ATOM   2424  C CB   . THR A 1 203 ? -10.851 11.449  15.106 1.00 8.40  ?  169  THR A CB   1 
ATOM   2425  O OG1  . THR A 1 203 ? -11.099 12.667  15.823 1.00 7.81  ?  169  THR A OG1  1 
ATOM   2426  C CG2  . THR A 1 203 ? -12.191 10.820  14.803 1.00 9.26  ?  169  THR A CG2  1 
ATOM   2427  H H    . THR A 1 203 ? -10.180 8.732   15.132 1.00 8.47  ?  169  THR A H    1 
ATOM   2428  H HA   . THR A 1 203 ? -9.175  11.028  16.196 1.00 8.51  ?  169  THR A HA   1 
ATOM   2429  H HB   . THR A 1 203 ? -10.390 11.630  14.272 1.00 10.08 ?  169  THR A HB   1 
ATOM   2430  H HG1  . THR A 1 203 ? -10.371 13.037  16.022 1.00 9.37  ?  169  THR A HG1  1 
ATOM   2431  H HG21 . THR A 1 203 ? -12.664 11.350  14.143 1.00 11.11 ?  169  THR A HG21 1 
ATOM   2432  H HG22 . THR A 1 203 ? -12.065 9.923   14.455 1.00 11.11 ?  169  THR A HG22 1 
ATOM   2433  H HG23 . THR A 1 203 ? -12.725 10.772  15.611 1.00 11.11 ?  169  THR A HG23 1 
ATOM   2434  N N    . PHE A 1 204 ? -10.424 10.879  18.255 1.00 7.04  ?  170  PHE A N    1 
ATOM   2435  C CA   . PHE A 1 204 ? -11.096 10.785  19.550 1.00 6.35  ?  170  PHE A CA   1 
ATOM   2436  C C    . PHE A 1 204 ? -12.118 11.907  19.600 1.00 6.35  ?  170  PHE A C    1 
ATOM   2437  O O    . PHE A 1 204 ? -11.747 13.078  19.645 1.00 7.03  ?  170  PHE A O    1 
ATOM   2438  C CB   . PHE A 1 204 ? -10.056 10.985  20.650 1.00 8.44  ?  170  PHE A CB   1 
ATOM   2439  C CG   . PHE A 1 204 ? -10.594 10.935  22.066 1.00 6.64  ?  170  PHE A CG   1 
ATOM   2440  C CD1  . PHE A 1 204 ? -11.323 11.985  22.625 1.00 8.59  ?  170  PHE A CD1  1 
ATOM   2441  C CD2  . PHE A 1 204 ? -10.284 9.856   22.872 1.00 8.57  ?  170  PHE A CD2  1 
ATOM   2442  C CE1  . PHE A 1 204 ? -11.778 11.899  23.944 1.00 8.81  ?  170  PHE A CE1  1 
ATOM   2443  C CE2  . PHE A 1 204 ? -10.724 9.784   24.180 1.00 8.71  ?  170  PHE A CE2  1 
ATOM   2444  C CZ   . PHE A 1 204 ? -11.467 10.809  24.713 1.00 9.16  ?  170  PHE A CZ   1 
ATOM   2445  H H    . PHE A 1 204 ? -9.872  11.538  18.229 1.00 8.45  ?  170  PHE A H    1 
ATOM   2446  H HA   . PHE A 1 204 ? -11.543 9.932   19.658 1.00 7.62  ?  170  PHE A HA   1 
ATOM   2447  H HB2  . PHE A 1 204 ? -9.388  10.287  20.569 1.00 10.12 ?  170  PHE A HB2  1 
ATOM   2448  H HB3  . PHE A 1 204 ? -9.644  11.854  20.527 1.00 10.12 ?  170  PHE A HB3  1 
ATOM   2449  H HD1  . PHE A 1 204 ? -11.508 12.744  22.119 1.00 10.31 ?  170  PHE A HD1  1 
ATOM   2450  H HD2  . PHE A 1 204 ? -9.769  9.163   22.527 1.00 10.29 ?  170  PHE A HD2  1 
ATOM   2451  H HE1  . PHE A 1 204 ? -12.294 12.585  24.301 1.00 10.58 ?  170  PHE A HE1  1 
ATOM   2452  H HE2  . PHE A 1 204 ? -10.518 9.041   24.700 1.00 10.45 ?  170  PHE A HE2  1 
ATOM   2453  H HZ   . PHE A 1 204 ? -11.758 10.763  25.595 1.00 10.99 ?  170  PHE A HZ   1 
ATOM   2454  N N    . ILE A 1 205 ? -13.405 11.554  19.543 1.00 7.11  ?  171  ILE A N    1 
ATOM   2455  C CA   . ILE A 1 205 ? -14.469 12.547  19.591 1.00 7.48  ?  171  ILE A CA   1 
ATOM   2456  C C    . ILE A 1 205 ? -14.870 12.782  21.033 1.00 7.24  ?  171  ILE A C    1 
ATOM   2457  O O    . ILE A 1 205 ? -15.229 11.847  21.750 1.00 7.72  ?  171  ILE A O    1 
ATOM   2458  C CB   . ILE A 1 205 ? -15.676 12.103  18.761 1.00 7.94  ?  171  ILE A CB   1 
ATOM   2459  C CG1  . ILE A 1 205 ? -15.259 11.825  17.322 1.00 9.14  ?  171  ILE A CG1  1 
ATOM   2460  C CG2  . ILE A 1 205 ? -16.763 13.188  18.811 1.00 9.38  ?  171  ILE A CG2  1 
ATOM   2461  C CD1  . ILE A 1 205 ? -14.515 12.955  16.662 1.00 10.94 ?  171  ILE A CD1  1 
ATOM   2462  H H    . ILE A 1 205 ? -13.683 10.743  19.477 1.00 8.53  ?  171  ILE A H    1 
ATOM   2463  H HA   . ILE A 1 205 ? -14.132 13.380  19.228 1.00 8.97  ?  171  ILE A HA   1 
ATOM   2464  H HB   . ILE A 1 205 ? -16.030 11.281  19.136 1.00 9.53  ?  171  ILE A HB   1 
ATOM   2465  H HG12 . ILE A 1 205 ? -14.681 11.047  17.312 1.00 10.97 ?  171  ILE A HG12 1 
ATOM   2466  H HG13 . ILE A 1 205 ? -16.057 11.653  16.797 1.00 10.97 ?  171  ILE A HG13 1 
ATOM   2467  H HG21 . ILE A 1 205 ? -17.472 12.953  18.193 1.00 11.26 ?  171  ILE A HG21 1 
ATOM   2468  H HG22 . ILE A 1 205 ? -17.116 13.241  19.714 1.00 11.26 ?  171  ILE A HG22 1 
ATOM   2469  H HG23 . ILE A 1 205 ? -16.372 14.039  18.559 1.00 11.26 ?  171  ILE A HG23 1 
ATOM   2470  H HD11 . ILE A 1 205 ? -14.467 12.787  15.708 1.00 13.13 ?  171  ILE A HD11 1 
ATOM   2471  H HD12 . ILE A 1 205 ? -14.989 13.785  16.828 1.00 13.13 ?  171  ILE A HD12 1 
ATOM   2472  H HD13 . ILE A 1 205 ? -13.621 13.005  17.035 1.00 13.13 ?  171  ILE A HD13 1 
ATOM   2473  N N    . ASP A 1 206 ? -14.837 14.041  21.448 1.00 6.24  ?  172  ASP A N    1 
ATOM   2474  C CA   . ASP A 1 206 ? -15.157 14.449  22.803 1.00 7.46  ?  172  ASP A CA   1 
ATOM   2475  C C    . ASP A 1 206 ? -16.393 15.345  22.829 1.00 6.79  ?  172  ASP A C    1 
ATOM   2476  O O    . ASP A 1 206 ? -16.725 16.019  21.849 1.00 7.09  ?  172  ASP A O    1 
ATOM   2477  C CB   . ASP A 1 206 ? -13.954 15.173  23.446 1.00 6.57  ?  172  ASP A CB   1 
ATOM   2478  C CG   . ASP A 1 206 ? -14.119 15.362  24.931 1.00 7.57  ?  172  ASP A CG   1 
ATOM   2479  O OD1  . ASP A 1 206 ? -14.802 14.519  25.560 1.00 7.24  ?  172  ASP A OD1  1 
ATOM   2480  O OD2  . ASP A 1 206 ? -13.541 16.343  25.450 1.00 8.71  ?  172  ASP A OD2  1 
ATOM   2481  H H    . ASP A 1 206 ? -14.623 14.702  20.941 1.00 7.49  ?  172  ASP A H    1 
ATOM   2482  H HA   . ASP A 1 206 ? -15.371 13.666  23.333 1.00 8.95  ?  172  ASP A HA   1 
ATOM   2483  H HB2  . ASP A 1 206 ? -13.152 14.648  23.297 1.00 7.89  ?  172  ASP A HB2  1 
ATOM   2484  H HB3  . ASP A 1 206 ? -13.858 16.049  23.041 1.00 7.89  ?  172  ASP A HB3  1 
ATOM   2485  N N    . ALA A 1 207 ? -17.062 15.316  23.991 1.00 7.35  ?  173  ALA A N    1 
ATOM   2486  C CA   . ALA A 1 207 ? -18.220 16.138  24.355 1.00 8.37  ?  173  ALA A CA   1 
ATOM   2487  C C    . ALA A 1 207 ? -19.549 15.622  23.816 1.00 7.09  ?  173  ALA A C    1 
ATOM   2488  O O    . ALA A 1 207 ? -20.576 16.333  23.869 1.00 8.01  ?  173  ALA A O    1 
ATOM   2489  C CB   . ALA A 1 207 ? -18.011 17.629  24.082 1.00 8.25  ?  173  ALA A CB   1 
ATOM   2490  H H    . ALA A 1 207 ? -16.843 14.785  24.631 1.00 8.82  ?  173  ALA A H    1 
ATOM   2491  H HA   . ALA A 1 207 ? -18.317 16.072  25.318 1.00 10.04 ?  173  ALA A HA   1 
ATOM   2492  H HB1  . ALA A 1 207 ? -18.771 18.123  24.428 1.00 9.90  ?  173  ALA A HB1  1 
ATOM   2493  H HB2  . ALA A 1 207 ? -17.198 17.920  24.523 1.00 9.90  ?  173  ALA A HB2  1 
ATOM   2494  H HB3  . ALA A 1 207 ? -17.936 17.767  23.124 1.00 9.90  ?  173  ALA A HB3  1 
ATOM   2495  N N    . ASN A 1 208 ? -19.553 14.372  23.360 1.00 7.17  ?  174  ASN A N    1 
ATOM   2496  C CA   . ASN A 1 208 ? -20.791 13.694  23.011 1.00 7.25  ?  174  ASN A CA   1 
ATOM   2497  C C    . ASN A 1 208 ? -21.803 13.804  24.133 1.00 8.24  ?  174  ASN A C    1 
ATOM   2498  O O    . ASN A 1 208 ? -22.998 13.995  23.878 1.00 8.10  ?  174  ASN A O    1 
ATOM   2499  C CB   . ASN A 1 208 ? -20.500 12.209  22.764 1.00 8.48  ?  174  ASN A CB   1 
ATOM   2500  C CG   . ASN A 1 208 ? -19.257 11.990  21.920 1.00 8.83  ?  174  ASN A CG   1 
ATOM   2501  O OD1  . ASN A 1 208 ? -18.131 11.972  22.415 1.00 12.24 ?  174  ASN A OD1  1 
ATOM   2502  N ND2  . ASN A 1 208 ? -19.445 11.854  20.647 1.00 12.30 ?  174  ASN A ND2  1 
ATOM   2503  H H    . ASN A 1 208 ? -18.848 13.894  23.243 1.00 8.60  ?  174  ASN A H    1 
ATOM   2504  H HA   . ASN A 1 208 ? -21.156 14.099  22.209 1.00 8.70  ?  174  ASN A HA   1 
ATOM   2505  H HB2  . ASN A 1 208 ? -20.366 11.767  23.617 1.00 10.17 ?  174  ASN A HB2  1 
ATOM   2506  H HB3  . ASN A 1 208 ? -21.253 11.812  22.299 1.00 10.17 ?  174  ASN A HB3  1 
ATOM   2507  H HD21 . ASN A 1 208 ? -18.773 11.727  20.124 1.00 14.76 ?  174  ASN A HD21 1 
ATOM   2508  H HD22 . ASN A 1 208 ? -20.241 11.890  20.323 1.00 14.76 ?  174  ASN A HD22 1 
ATOM   2509  N N    . ILE A 1 209 ? -21.351 13.658  25.375 1.00 7.53  ?  175  ILE A N    1 
ATOM   2510  C CA   . ILE A 1 209 ? -22.274 13.630  26.506 1.00 8.34  ?  175  ILE A CA   1 
ATOM   2511  C C    . ILE A 1 209 ? -22.868 15.008  26.762 1.00 7.70  ?  175  ILE A C    1 
ATOM   2512  O O    . ILE A 1 209 ? -24.030 15.109  27.174 1.00 8.69  ?  175  ILE A O    1 
ATOM   2513  C CB   . ILE A 1 209 ? -21.569 13.011  27.718 1.00 7.51  ?  175  ILE A CB   1 
ATOM   2514  C CG1  . ILE A 1 209 ? -21.300 11.537  27.404 1.00 9.44  ?  175  ILE A CG1  1 
ATOM   2515  C CG2  . ILE A 1 209 ? -22.419 13.164  28.972 1.00 9.24  ?  175  ILE A CG2  1 
ATOM   2516  C CD1  . ILE A 1 209 ? -20.356 10.862  28.356 1.00 10.90 ?  175  ILE A CD1  1 
ATOM   2517  H H    . ILE A 1 209 ? -20.522 13.575  25.590 1.00 9.04  ?  175  ILE A H    1 
ATOM   2518  H HA   . ILE A 1 209 ? -23.032 13.061  26.301 1.00 10.01 ?  175  ILE A HA   1 
ATOM   2519  H HB   . ILE A 1 209 ? -20.731 13.468  27.887 1.00 9.01  ?  175  ILE A HB   1 
ATOM   2520  H HG12 . ILE A 1 209 ? -22.142 11.055  27.435 1.00 11.33 ?  175  ILE A HG12 1 
ATOM   2521  H HG13 . ILE A 1 209 ? -20.915 11.475  26.515 1.00 11.33 ?  175  ILE A HG13 1 
ATOM   2522  H HG21 . ILE A 1 209 ? -22.008 12.665  29.695 1.00 11.09 ?  175  ILE A HG21 1 
ATOM   2523  H HG22 . ILE A 1 209 ? -22.470 14.104  29.206 1.00 11.09 ?  175  ILE A HG22 1 
ATOM   2524  H HG23 . ILE A 1 209 ? -23.308 12.818  28.796 1.00 11.09 ?  175  ILE A HG23 1 
ATOM   2525  H HD11 . ILE A 1 209 ? -20.242 9.938   28.085 1.00 13.08 ?  175  ILE A HD11 1 
ATOM   2526  H HD12 . ILE A 1 209 ? -19.502 11.321  28.332 1.00 13.08 ?  175  ILE A HD12 1 
ATOM   2527  H HD13 . ILE A 1 209 ? -20.728 10.901  29.250 1.00 13.08 ?  175  ILE A HD13 1 
ATOM   2528  N N    . LYS A 1 210 ? -22.117 16.083  26.489 1.00 7.58  ?  176  LYS A N    1 
ATOM   2529  C CA   . LYS A 1 210 ? -22.667 17.428  26.609 1.00 7.80  ?  176  LYS A CA   1 
ATOM   2530  C C    . LYS A 1 210 ? -23.782 17.655  25.601 1.00 8.22  ?  176  LYS A C    1 
ATOM   2531  O O    . LYS A 1 210 ? -24.740 18.375  25.889 1.00 8.86  ?  176  LYS A O    1 
ATOM   2532  C CB   . LYS A 1 210 ? -21.557 18.466  26.450 1.00 7.86  ?  176  LYS A CB   1 
ATOM   2533  C CG   . LYS A 1 210 ? -20.690 18.609  27.700 1.00 8.78  ?  176  LYS A CG   1 
ATOM   2534  C CD   . LYS A 1 210 ? -19.479 19.491  27.469 1.00 7.14  ?  176  LYS A CD   1 
ATOM   2535  C CE   . LYS A 1 210 ? -18.762 19.834  28.773 1.00 8.48  ?  176  LYS A CE   1 
ATOM   2536  N NZ   . LYS A 1 210 ? -18.091 18.660  29.369 1.00 8.71  ?  176  LYS A NZ   1 
ATOM   2537  H H    . LYS A 1 210 ? -21.296 16.056  26.236 1.00 9.10  ?  176  LYS A H    1 
ATOM   2538  H HA   . LYS A 1 210 ? -23.044 17.538  27.495 1.00 9.36  ?  176  LYS A HA   1 
ATOM   2539  H HB2  . LYS A 1 210 ? -20.981 18.202  25.715 1.00 9.44  ?  176  LYS A HB2  1 
ATOM   2540  H HB3  . LYS A 1 210 ? -21.958 19.329  26.263 1.00 9.44  ?  176  LYS A HB3  1 
ATOM   2541  H HG2  . LYS A 1 210 ? -21.220 19.005  28.410 1.00 10.54 ?  176  LYS A HG2  1 
ATOM   2542  H HG3  . LYS A 1 210 ? -20.376 17.732  27.970 1.00 10.54 ?  176  LYS A HG3  1 
ATOM   2543  H HD2  . LYS A 1 210 ? -18.852 19.028  26.892 1.00 8.57  ?  176  LYS A HD2  1 
ATOM   2544  H HD3  . LYS A 1 210 ? -19.763 20.320  27.053 1.00 8.57  ?  176  LYS A HD3  1 
ATOM   2545  H HE2  . LYS A 1 210 ? -18.088 20.510  28.597 1.00 10.17 ?  176  LYS A HE2  1 
ATOM   2546  H HE3  . LYS A 1 210 ? -19.409 20.170  29.413 1.00 10.17 ?  176  LYS A HE3  1 
ATOM   2547  H HZ1  . LYS A 1 210 ? -17.446 18.371  28.828 1.00 10.46 ?  176  LYS A HZ1  1 
ATOM   2548  H HZ2  . LYS A 1 210 ? -17.733 18.879  30.154 1.00 10.46 ?  176  LYS A HZ2  1 
ATOM   2549  H HZ3  . LYS A 1 210 ? -18.679 18.004  29.493 1.00 10.46 ?  176  LYS A HZ3  1 
ATOM   2550  N N    . VAL A 1 211 ? -23.666 17.079  24.407 1.00 7.49  ?  177  VAL A N    1 
ATOM   2551  C CA   . VAL A 1 211 ? -24.750 17.129  23.430 1.00 7.67  ?  177  VAL A CA   1 
ATOM   2552  C C    . VAL A 1 211 ? -25.943 16.314  23.897 1.00 8.25  ?  177  VAL A C    1 
ATOM   2553  O O    . VAL A 1 211 ? -27.097 16.755  23.780 1.00 9.12  ?  177  VAL A O    1 
ATOM   2554  C CB   . VAL A 1 211 ? -24.253 16.624  22.064 1.00 7.90  ?  177  VAL A CB   1 
ATOM   2555  C CG1  . VAL A 1 211 ? -25.440 16.440  21.104 1.00 8.88  ?  177  VAL A CG1  1 
ATOM   2556  C CG2  . VAL A 1 211 ? -23.186 17.537  21.485 1.00 9.04  ?  177  VAL A CG2  1 
ATOM   2557  H H    . VAL A 1 211 ? -22.970 16.652  24.137 1.00 8.99  ?  177  VAL A H    1 
ATOM   2558  H HA   . VAL A 1 211 ? -25.030 18.054  23.344 1.00 9.20  ?  177  VAL A HA   1 
ATOM   2559  H HB   . VAL A 1 211 ? -23.831 15.759  22.184 1.00 9.48  ?  177  VAL A HB   1 
ATOM   2560  H HG11 . VAL A 1 211 ? -25.100 16.261  20.213 1.00 10.66 ?  177  VAL A HG11 1 
ATOM   2561  H HG12 . VAL A 1 211 ? -25.979 15.694  21.408 1.00 10.66 ?  177  VAL A HG12 1 
ATOM   2562  H HG13 . VAL A 1 211 ? -25.971 17.252  21.099 1.00 10.66 ?  177  VAL A HG13 1 
ATOM   2563  H HG21 . VAL A 1 211 ? -22.846 17.144  20.665 1.00 10.85 ?  177  VAL A HG21 1 
ATOM   2564  H HG22 . VAL A 1 211 ? -23.579 18.403  21.298 1.00 10.85 ?  177  VAL A HG22 1 
ATOM   2565  H HG23 . VAL A 1 211 ? -22.467 17.631  22.129 1.00 10.85 ?  177  VAL A HG23 1 
ATOM   2566  N N    . LEU A 1 212 ? -25.705 15.115  24.418 1.00 8.20  ?  178  LEU A N    1 
ATOM   2567  C CA   . LEU A 1 212 ? -26.759 14.122  24.583 1.00 8.48  ?  178  LEU A CA   1 
ATOM   2568  C C    . LEU A 1 212 ? -27.493 14.184  25.913 1.00 10.76 ?  178  LEU A C    1 
ATOM   2569  O O    . LEU A 1 212 ? -28.617 13.667  25.992 1.00 11.73 ?  178  LEU A O    1 
ATOM   2570  C CB   . LEU A 1 212 ? -26.197 12.721  24.354 1.00 9.32  ?  178  LEU A CB   1 
ATOM   2571  C CG   . LEU A 1 212 ? -25.721 12.485  22.918 1.00 10.31 ?  178  LEU A CG   1 
ATOM   2572  C CD1  . LEU A 1 212 ? -24.883 11.232  22.851 1.00 11.75 ?  178  LEU A CD1  1 
ATOM   2573  C CD2  . LEU A 1 212 ? -26.896 12.415  21.959 1.00 11.89 ?  178  LEU A CD2  1 
ATOM   2574  H H    . LEU A 1 212 ? -24.933 14.850  24.687 1.00 9.84  ?  178  LEU A H    1 
ATOM   2575  H HA   . LEU A 1 212 ? -27.433 14.288  23.905 1.00 10.18 ?  178  LEU A HA   1 
ATOM   2576  H HB2  . LEU A 1 212 ? -25.439 12.588  24.945 1.00 11.18 ?  178  LEU A HB2  1 
ATOM   2577  H HB3  . LEU A 1 212 ? -26.889 12.071  24.550 1.00 11.18 ?  178  LEU A HB3  1 
ATOM   2578  H HG   . LEU A 1 212 ? -25.170 13.232  22.637 1.00 12.37 ?  178  LEU A HG   1 
ATOM   2579  H HD11 . LEU A 1 212 ? -24.634 11.068  21.928 1.00 14.10 ?  178  LEU A HD11 1 
ATOM   2580  H HD12 . LEU A 1 212 ? -24.088 11.355  23.392 1.00 14.10 ?  178  LEU A HD12 1 
ATOM   2581  H HD13 . LEU A 1 212 ? -25.402 10.487  23.190 1.00 14.10 ?  178  LEU A HD13 1 
ATOM   2582  H HD21 . LEU A 1 212 ? -26.569 12.183  21.076 1.00 14.27 ?  178  LEU A HD21 1 
ATOM   2583  H HD22 . LEU A 1 212 ? -27.517 11.738  22.270 1.00 14.27 ?  178  LEU A HD22 1 
ATOM   2584  H HD23 . LEU A 1 212 ? -27.335 13.279  21.934 1.00 14.27 ?  178  LEU A HD23 1 
ATOM   2585  N N    . VAL A 1 213 ? -26.930 14.814  26.935 1.00 9.33  ?  179  VAL A N    1 
ATOM   2586  C CA   . VAL A 1 213 ? -27.635 15.058  28.192 1.00 8.90  ?  179  VAL A CA   1 
ATOM   2587  C C    . VAL A 1 213 ? -28.413 16.356  28.013 1.00 9.44  ?  179  VAL A C    1 
ATOM   2588  O O    . VAL A 1 213 ? -27.790 17.419  27.888 1.00 10.06 ?  179  VAL A O    1 
ATOM   2589  C CB   . VAL A 1 213 ? -26.660 15.162  29.371 1.00 8.84  ?  179  VAL A CB   1 
ATOM   2590  C CG1  . VAL A 1 213 ? -27.341 15.684  30.622 1.00 11.96 ?  179  VAL A CG1  1 
ATOM   2591  C CG2  . VAL A 1 213 ? -26.029 13.813  29.634 1.00 11.02 ?  179  VAL A CG2  1 
ATOM   2592  H H    . VAL A 1 213 ? -26.125 15.117  26.928 1.00 11.20 ?  179  VAL A H    1 
ATOM   2593  H HA   . VAL A 1 213 ? -28.255 14.334  28.372 1.00 10.68 ?  179  VAL A HA   1 
ATOM   2594  H HB   . VAL A 1 213 ? -25.966 15.799  29.139 1.00 10.60 ?  179  VAL A HB   1 
ATOM   2595  H HG11 . VAL A 1 213 ? -26.825 15.415  31.398 1.00 14.35 ?  179  VAL A HG11 1 
ATOM   2596  H HG12 . VAL A 1 213 ? -27.388 16.652  30.576 1.00 14.35 ?  179  VAL A HG12 1 
ATOM   2597  H HG13 . VAL A 1 213 ? -28.235 15.312  30.674 1.00 14.35 ?  179  VAL A HG13 1 
ATOM   2598  H HG21 . VAL A 1 213 ? -25.355 13.908  30.324 1.00 13.22 ?  179  VAL A HG21 1 
ATOM   2599  H HG22 . VAL A 1 213 ? -26.717 13.194  29.926 1.00 13.22 ?  179  VAL A HG22 1 
ATOM   2600  H HG23 . VAL A 1 213 ? -25.621 13.490  28.815 1.00 13.22 ?  179  VAL A HG23 1 
ATOM   2601  N N    . PRO A 1 214 ? -29.746 16.317  27.917 1.00 9.19  ?  180  PRO A N    1 
ATOM   2602  C CA   . PRO A 1 214 ? -30.455 17.520  27.458 1.00 10.04 ?  180  PRO A CA   1 
ATOM   2603  C C    . PRO A 1 214 ? -30.213 18.761  28.281 1.00 8.34  ?  180  PRO A C    1 
ATOM   2604  O O    . PRO A 1 214 ? -30.157 19.855  27.722 1.00 9.17  ?  180  PRO A O    1 
ATOM   2605  C CB   . PRO A 1 214 ? -31.929 17.090  27.455 1.00 11.49 ?  180  PRO A CB   1 
ATOM   2606  C CG   . PRO A 1 214 ? -31.896 15.628  27.218 1.00 13.24 ?  180  PRO A CG   1 
ATOM   2607  C CD   . PRO A 1 214 ? -30.632 15.139  27.964 1.00 10.18 ?  180  PRO A CD   1 
ATOM   2608  H HA   . PRO A 1 214 ? -30.178 17.711  26.548 1.00 12.05 ?  180  PRO A HA   1 
ATOM   2609  H HB2  . PRO A 1 214 ? -32.336 17.295  28.312 1.00 13.79 ?  180  PRO A HB2  1 
ATOM   2610  H HB3  . PRO A 1 214 ? -32.406 17.547  26.744 1.00 13.79 ?  180  PRO A HB3  1 
ATOM   2611  H HG2  . PRO A 1 214 ? -32.695 15.214  27.580 1.00 15.89 ?  180  PRO A HG2  1 
ATOM   2612  H HG3  . PRO A 1 214 ? -31.830 15.447  26.267 1.00 15.89 ?  180  PRO A HG3  1 
ATOM   2613  H HD2  . PRO A 1 214 ? -30.842 14.899  28.880 1.00 12.22 ?  180  PRO A HD2  1 
ATOM   2614  H HD3  . PRO A 1 214 ? -30.230 14.384  27.507 1.00 12.22 ?  180  PRO A HD3  1 
ATOM   2615  N N    . SER A 1 215 ? -30.055 18.626  29.596 1.00 10.28 ?  181  SER A N    1 
ATOM   2616  C CA   . SER A 1 215 ? -29.947 19.821  30.415 1.00 9.28  ?  181  SER A CA   1 
ATOM   2617  C C    . SER A 1 215 ? -28.678 20.620  30.146 1.00 9.34  ?  181  SER A C    1 
ATOM   2618  O O    . SER A 1 215 ? -28.645 21.821  30.429 1.00 10.04 ?  181  SER A O    1 
ATOM   2619  C CB   . SER A 1 215 ? -30.048 19.485  31.898 1.00 11.08 ?  181  SER A CB   1 
ATOM   2620  O OG   . SER A 1 215 ? -28.853 18.855  32.346 1.00 11.46 ?  181  SER A OG   1 
ATOM   2621  H H    . SER A 1 215 ? -30.009 17.879  30.020 1.00 12.33 ?  181  SER A H    1 
ATOM   2622  H HA   . SER A 1 215 ? -30.703 20.389  30.196 1.00 11.13 ?  181  SER A HA   1 
ATOM   2623  H HB2  . SER A 1 215 ? -30.182 20.304  32.400 1.00 13.30 ?  181  SER A HB2  1 
ATOM   2624  H HB3  . SER A 1 215 ? -30.796 18.883  32.037 1.00 13.30 ?  181  SER A HB3  1 
ATOM   2625  H HG   . SER A 1 215 ? -28.745 18.125  31.943 1.00 13.75 ?  181  SER A HG   1 
ATOM   2626  N N    . PHE A 1 216 ? -27.620 19.998  29.611 1.00 8.13  ?  182  PHE A N    1 
ATOM   2627  C CA   . PHE A 1 216 ? -26.378 20.746  29.439 1.00 8.98  ?  182  PHE A CA   1 
ATOM   2628  C C    . PHE A 1 216 ? -26.590 21.949  28.531 1.00 8.29  ?  182  PHE A C    1 
ATOM   2629  O O    . PHE A 1 216 ? -26.235 23.087  28.877 1.00 9.40  ?  182  PHE A O    1 
ATOM   2630  C CB   . PHE A 1 216 ? -25.232 19.870  28.904 1.00 8.52  ?  182  PHE A CB   1 
ATOM   2631  C CG   . PHE A 1 216 ? -23.955 20.626  28.808 1.00 7.26  ?  182  PHE A CG   1 
ATOM   2632  C CD1  . PHE A 1 216 ? -23.179 20.819  29.936 1.00 10.05 ?  182  PHE A CD1  1 
ATOM   2633  C CD2  . PHE A 1 216 ? -23.561 21.236  27.622 1.00 9.02  ?  182  PHE A CD2  1 
ATOM   2634  C CE1  . PHE A 1 216 ? -22.016 21.575  29.881 1.00 8.44  ?  182  PHE A CE1  1 
ATOM   2635  C CE2  . PHE A 1 216 ? -22.399 21.998  27.574 1.00 9.68  ?  182  PHE A CE2  1 
ATOM   2636  C CZ   . PHE A 1 216 ? -21.635 22.169  28.715 1.00 8.71  ?  182  PHE A CZ   1 
ATOM   2637  H H    . PHE A 1 216 ? -27.599 19.179  29.352 1.00 9.76  ?  182  PHE A H    1 
ATOM   2638  H HA   . PHE A 1 216 ? -26.105 21.050  30.319 1.00 10.78 ?  182  PHE A HA   1 
ATOM   2639  H HB2  . PHE A 1 216 ? -25.097 19.120  29.505 1.00 10.23 ?  182  PHE A HB2  1 
ATOM   2640  H HB3  . PHE A 1 216 ? -25.463 19.548  28.019 1.00 10.23 ?  182  PHE A HB3  1 
ATOM   2641  H HD1  . PHE A 1 216 ? -23.440 20.438  30.743 1.00 12.06 ?  182  PHE A HD1  1 
ATOM   2642  H HD2  . PHE A 1 216 ? -24.078 21.134  26.856 1.00 10.82 ?  182  PHE A HD2  1 
ATOM   2643  H HE1  . PHE A 1 216 ? -21.493 21.675  30.643 1.00 10.12 ?  182  PHE A HE1  1 
ATOM   2644  H HE2  . PHE A 1 216 ? -22.136 22.394  26.774 1.00 11.61 ?  182  PHE A HE2  1 
ATOM   2645  H HZ   . PHE A 1 216 ? -20.864 22.688  28.686 1.00 10.46 ?  182  PHE A HZ   1 
ATOM   2646  N N    . PHE A 1 217 ? -27.124 21.713  27.330 1.00 7.81  ?  183  PHE A N    1 
ATOM   2647  C CA   . PHE A 1 217 ? -27.421 22.832  26.442 1.00 8.75  ?  183  PHE A CA   1 
ATOM   2648  C C    . PHE A 1 217 ? -28.791 23.465  26.681 1.00 8.43  ?  183  PHE A C    1 
ATOM   2649  O O    . PHE A 1 217 ? -28.932 24.670  26.445 1.00 8.74  ?  183  PHE A O    1 
ATOM   2650  C CB   . PHE A 1 217 ? -27.231 22.472  24.966 1.00 8.89  ?  183  PHE A CB   1 
ATOM   2651  C CG   . PHE A 1 217 ? -25.785 22.456  24.540 1.00 7.40  ?  183  PHE A CG   1 
ATOM   2652  C CD1  . PHE A 1 217 ? -25.002 23.583  24.637 1.00 9.35  ?  183  PHE A CD1  1 
ATOM   2653  C CD2  . PHE A 1 217 ? -25.207 21.300  24.067 1.00 8.88  ?  183  PHE A CD2  1 
ATOM   2654  C CE1  . PHE A 1 217 ? -23.653 23.561  24.250 1.00 8.92  ?  183  PHE A CE1  1 
ATOM   2655  C CE2  . PHE A 1 217 ? -23.874 21.268  23.690 1.00 9.42  ?  183  PHE A CE2  1 
ATOM   2656  C CZ   . PHE A 1 217 ? -23.096 22.398  23.785 1.00 8.48  ?  183  PHE A CZ   1 
ATOM   2657  H H    . PHE A 1 217 ? -27.317 20.935  27.018 1.00 9.38  ?  183  PHE A H    1 
ATOM   2658  H HA   . PHE A 1 217 ? -26.762 23.520  26.624 1.00 10.50 ?  183  PHE A HA   1 
ATOM   2659  H HB2  . PHE A 1 217 ? -27.599 21.588  24.809 1.00 10.67 ?  183  PHE A HB2  1 
ATOM   2660  H HB3  . PHE A 1 217 ? -27.696 23.126  24.421 1.00 10.67 ?  183  PHE A HB3  1 
ATOM   2661  H HD1  . PHE A 1 217 ? -25.372 24.371  24.965 1.00 11.22 ?  183  PHE A HD1  1 
ATOM   2662  H HD2  . PHE A 1 217 ? -25.720 20.527  24.000 1.00 10.66 ?  183  PHE A HD2  1 
ATOM   2663  H HE1  . PHE A 1 217 ? -23.139 24.334  24.309 1.00 10.71 ?  183  PHE A HE1  1 
ATOM   2664  H HE2  . PHE A 1 217 ? -23.504 20.477  23.370 1.00 11.31 ?  183  PHE A HE2  1 
ATOM   2665  H HZ   . PHE A 1 217 ? -22.200 22.373  23.536 1.00 10.18 ?  183  PHE A HZ   1 
ATOM   2666  N N    A SER A 1 218 ? -29.794 22.724  27.166 0.73 9.30  ?  184  SER A N    1 
ATOM   2667  N N    B SER A 1 218 ? -29.790 22.716  27.159 0.27 9.35  ?  184  SER A N    1 
ATOM   2668  C CA   A SER A 1 218 ? -31.085 23.397  27.313 0.73 9.76  ?  184  SER A CA   1 
ATOM   2669  C CA   B SER A 1 218 ? -31.100 23.331  27.368 0.27 9.84  ?  184  SER A CA   1 
ATOM   2670  C C    A SER A 1 218 ? -31.015 24.502  28.355 0.73 10.09 ?  184  SER A C    1 
ATOM   2671  C C    B SER A 1 218 ? -31.016 24.483  28.361 0.27 10.09 ?  184  SER A C    1 
ATOM   2672  O O    A SER A 1 218 ? -31.713 25.517  28.215 0.73 11.04 ?  184  SER A O    1 
ATOM   2673  O O    B SER A 1 218 ? -31.710 25.497  28.207 0.27 11.12 ?  184  SER A O    1 
ATOM   2674  C CB   A SER A 1 218 ? -32.196 22.414  27.631 0.73 11.70 ?  184  SER A CB   1 
ATOM   2675  C CB   B SER A 1 218 ? -32.115 22.291  27.832 0.27 11.69 ?  184  SER A CB   1 
ATOM   2676  O OG   A SER A 1 218 ? -32.120 21.955  28.958 0.73 11.23 ?  184  SER A OG   1 
ATOM   2677  O OG   B SER A 1 218 ? -32.403 21.372  26.795 0.27 10.71 ?  184  SER A OG   1 
ATOM   2678  H H    A SER A 1 218 ? -29.754 21.897  27.398 0.73 11.17 ?  184  SER A H    1 
ATOM   2679  H H    B SER A 1 218 ? -29.736 21.882  27.361 0.27 11.23 ?  184  SER A H    1 
ATOM   2680  H HA   A SER A 1 218 ? -31.316 23.798  26.460 0.73 11.72 ?  184  SER A HA   1 
ATOM   2681  H HA   B SER A 1 218 ? -31.412 23.685  26.520 0.27 11.81 ?  184  SER A HA   1 
ATOM   2682  H HB2  A SER A 1 218 ? -33.050 22.855  27.501 0.73 14.04 ?  184  SER A HB2  1 
ATOM   2683  H HB2  B SER A 1 218 ? -31.750 21.809  28.590 0.27 14.02 ?  184  SER A HB2  1 
ATOM   2684  H HB3  A SER A 1 218 ? -32.121 21.653  27.033 0.73 14.04 ?  184  SER A HB3  1 
ATOM   2685  H HB3  B SER A 1 218 ? -32.934 22.743  28.090 0.27 14.02 ?  184  SER A HB3  1 
ATOM   2686  H HG   A SER A 1 218 ? -32.525 21.223  29.032 0.73 13.47 ?  184  SER A HG   1 
ATOM   2687  H HG   B SER A 1 218 ? -33.207 21.443  26.562 0.27 12.85 ?  184  SER A HG   1 
ATOM   2688  N N    . SER A 1 219 ? -30.163 24.353  29.380 1.00 9.27  ?  185  SER A N    1 
ATOM   2689  C CA   . SER A 1 219 ? -29.999 25.368  30.408 1.00 9.66  ?  185  SER A CA   1 
ATOM   2690  C C    . SER A 1 219 ? -29.222 26.575  29.914 1.00 11.18 ?  185  SER A C    1 
ATOM   2691  O O    . SER A 1 219 ? -29.151 27.585  30.630 1.00 14.29 ?  185  SER A O    1 
ATOM   2692  C CB   . SER A 1 219 ? -29.317 24.775  31.640 1.00 10.98 ?  185  SER A CB   1 
ATOM   2693  O OG   . SER A 1 219 ? -27.979 24.358  31.340 1.00 12.64 ?  185  SER A OG   1 
ATOM   2694  H H    . SER A 1 219 ? -29.666 23.661  29.496 1.00 11.13 ?  185  SER A H    1 
ATOM   2695  H HA   . SER A 1 219 ? -30.878 25.672  30.683 1.00 11.59 ?  185  SER A HA   1 
ATOM   2696  H HB2  . SER A 1 219 ? -29.287 25.449  32.338 1.00 13.18 ?  185  SER A HB2  1 
ATOM   2697  H HB3  . SER A 1 219 ? -29.825 24.007  31.942 1.00 13.18 ?  185  SER A HB3  1 
ATOM   2698  H HG   . SER A 1 219 ? -27.994 23.674  30.852 1.00 15.17 ?  185  SER A HG   1 
ATOM   2699  N N    . LYS A 1 220 ? -28.651 26.506  28.709 1.00 10.14 ?  186  LYS A N    1 
ATOM   2700  C CA   . LYS A 1 220 ? -27.892 27.600  28.113 1.00 9.57  ?  186  LYS A CA   1 
ATOM   2701  C C    . LYS A 1 220 ? -28.602 28.247  26.936 1.00 9.21  ?  186  LYS A C    1 
ATOM   2702  O O    . LYS A 1 220 ? -28.544 29.468  26.774 1.00 11.00 ?  186  LYS A O    1 
ATOM   2703  C CB   . LYS A 1 220 ? -26.524 27.090  27.621 1.00 11.50 ?  186  LYS A CB   1 
ATOM   2704  C CG   . LYS A 1 220 ? -25.607 26.574  28.725 1.00 12.07 ?  186  LYS A CG   1 
ATOM   2705  C CD   . LYS A 1 220 ? -24.336 25.936  28.122 1.00 12.96 ?  186  LYS A CD   1 
ATOM   2706  C CE   . LYS A 1 220 ? -23.349 25.491  29.170 1.00 15.20 ?  186  LYS A CE   1 
ATOM   2707  N NZ   . LYS A 1 220 ? -23.954 24.530  30.103 1.00 15.31 ?  186  LYS A NZ   1 
ATOM   2708  H H    . LYS A 1 220 ? -28.692 25.811  28.203 1.00 12.17 ?  186  LYS A H    1 
ATOM   2709  H HA   . LYS A 1 220 ? -27.743 28.275  28.794 1.00 11.49 ?  186  LYS A HA   1 
ATOM   2710  H HB2  . LYS A 1 220 ? -26.671 26.361  26.998 1.00 13.79 ?  186  LYS A HB2  1 
ATOM   2711  H HB3  . LYS A 1 220 ? -26.064 27.819  27.175 1.00 13.79 ?  186  LYS A HB3  1 
ATOM   2712  H HG2  . LYS A 1 220 ? -25.341 27.311  29.297 1.00 14.48 ?  186  LYS A HG2  1 
ATOM   2713  H HG3  . LYS A 1 220 ? -26.073 25.901  29.246 1.00 14.48 ?  186  LYS A HG3  1 
ATOM   2714  H HD2  . LYS A 1 220 ? -24.590 25.158  27.601 1.00 15.55 ?  186  LYS A HD2  1 
ATOM   2715  H HD3  . LYS A 1 220 ? -23.896 26.587  27.553 1.00 15.55 ?  186  LYS A HD3  1 
ATOM   2716  H HE2  . LYS A 1 220 ? -22.593 25.064  28.738 1.00 18.24 ?  186  LYS A HE2  1 
ATOM   2717  H HE3  . LYS A 1 220 ? -23.049 26.262  29.677 1.00 18.24 ?  186  LYS A HE3  1 
ATOM   2718  H HZ1  . LYS A 1 220 ? -23.328 24.185  30.633 1.00 18.37 ?  186  LYS A HZ1  1 
ATOM   2719  H HZ2  . LYS A 1 220 ? -24.566 24.937  30.605 1.00 18.37 ?  186  LYS A HZ2  1 
ATOM   2720  H HZ3  . LYS A 1 220 ? -24.345 23.870  29.650 1.00 18.37 ?  186  LYS A HZ3  1 
ATOM   2721  N N    . VAL A 1 221 ? -29.246 27.444  26.089 1.00 9.74  ?  187  VAL A N    1 
ATOM   2722  C CA   . VAL A 1 221 ? -29.770 27.921  24.817 1.00 9.78  ?  187  VAL A CA   1 
ATOM   2723  C C    . VAL A 1 221 ? -31.210 27.511  24.573 1.00 10.48 ?  187  VAL A C    1 
ATOM   2724  O O    . VAL A 1 221 ? -31.746 27.795  23.492 1.00 11.19 ?  187  VAL A O    1 
ATOM   2725  C CB   . VAL A 1 221 ? -28.877 27.499  23.627 1.00 10.61 ?  187  VAL A CB   1 
ATOM   2726  C CG1  . VAL A 1 221 ? -27.486 28.106  23.766 1.00 12.27 ?  187  VAL A CG1  1 
ATOM   2727  C CG2  . VAL A 1 221 ? -28.775 25.983  23.506 1.00 11.76 ?  187  VAL A CG2  1 
ATOM   2728  H H    . VAL A 1 221 ? -29.393 26.609  26.233 1.00 11.69 ?  187  VAL A H    1 
ATOM   2729  H HA   . VAL A 1 221 ? -29.764 28.890  24.844 1.00 11.73 ?  187  VAL A HA   1 
ATOM   2730  H HB   . VAL A 1 221 ? -29.290 27.831  22.815 1.00 12.73 ?  187  VAL A HB   1 
ATOM   2731  H HG11 . VAL A 1 221 ? -26.921 27.765  23.055 1.00 14.72 ?  187  VAL A HG11 1 
ATOM   2732  H HG12 . VAL A 1 221 ? -27.555 29.072  23.700 1.00 14.72 ?  187  VAL A HG12 1 
ATOM   2733  H HG13 . VAL A 1 221 ? -27.118 27.859  24.628 1.00 14.72 ?  187  VAL A HG13 1 
ATOM   2734  H HG21 . VAL A 1 221 ? -28.272 25.764  22.707 1.00 14.11 ?  187  VAL A HG21 1 
ATOM   2735  H HG22 . VAL A 1 221 ? -28.322 25.634  24.289 1.00 14.11 ?  187  VAL A HG22 1 
ATOM   2736  H HG23 . VAL A 1 221 ? -29.669 25.610  23.448 1.00 14.11 ?  187  VAL A HG23 1 
ATOM   2737  N N    . GLY A 1 222 ? -31.835 26.821  25.519 1.00 9.27  ?  188  GLY A N    1 
ATOM   2738  C CA   . GLY A 1 222 ? -33.234 26.442  25.438 1.00 9.82  ?  188  GLY A CA   1 
ATOM   2739  C C    . GLY A 1 222 ? -33.441 25.037  24.886 1.00 9.74  ?  188  GLY A C    1 
ATOM   2740  O O    . GLY A 1 222 ? -32.551 24.422  24.295 1.00 9.87  ?  188  GLY A O    1 
ATOM   2741  H H    . GLY A 1 222 ? -31.454 26.553  26.242 1.00 11.13 ?  188  GLY A H    1 
ATOM   2742  H HA2  . GLY A 1 222 ? -33.625 26.479  26.325 1.00 11.78 ?  188  GLY A HA2  1 
ATOM   2743  H HA3  . GLY A 1 222 ? -33.700 27.067  24.861 1.00 11.78 ?  188  GLY A HA3  1 
ATOM   2744  N N    . VAL A 1 223 ? -34.666 24.534  25.070 1.00 10.15 ?  189  VAL A N    1 
ATOM   2745  C CA   . VAL A 1 223 ? -35.018 23.153  24.741 1.00 10.04 ?  189  VAL A CA   1 
ATOM   2746  C C    . VAL A 1 223 ? -34.948 22.896  23.242 1.00 10.69 ?  189  VAL A C    1 
ATOM   2747  O O    . VAL A 1 223 ? -34.447 21.850  22.800 1.00 10.11 ?  189  VAL A O    1 
ATOM   2748  C CB   . VAL A 1 223 ? -36.405 22.807  25.326 1.00 12.47 ?  189  VAL A CB   1 
ATOM   2749  C CG1  . VAL A 1 223 ? -36.960 21.523  24.753 1.00 15.92 ?  189  VAL A CG1  1 
ATOM   2750  C CG2  . VAL A 1 223 ? -36.325 22.737  26.849 1.00 13.75 ?  189  VAL A CG2  1 
ATOM   2751  H H    . VAL A 1 223 ? -35.326 24.982  25.392 1.00 12.19 ?  189  VAL A H    1 
ATOM   2752  H HA   . VAL A 1 223 ? -34.360 22.571  25.153 1.00 12.05 ?  189  VAL A HA   1 
ATOM   2753  H HB   . VAL A 1 223 ? -37.025 23.511  25.076 1.00 14.97 ?  189  VAL A HB   1 
ATOM   2754  H HG11 . VAL A 1 223 ? -37.760 21.279  25.242 1.00 19.11 ?  189  VAL A HG11 1 
ATOM   2755  H HG12 . VAL A 1 223 ? -37.174 21.662  23.817 1.00 19.11 ?  189  VAL A HG12 1 
ATOM   2756  H HG13 . VAL A 1 223 ? -36.293 20.825  24.839 1.00 19.11 ?  189  VAL A HG13 1 
ATOM   2757  H HG21 . VAL A 1 223 ? -37.194 22.486  27.200 1.00 16.50 ?  189  VAL A HG21 1 
ATOM   2758  H HG22 . VAL A 1 223 ? -35.663 22.073  27.100 1.00 16.50 ?  189  VAL A HG22 1 
ATOM   2759  H HG23 . VAL A 1 223 ? -36.068 23.607  27.192 1.00 16.50 ?  189  VAL A HG23 1 
ATOM   2760  N N    . ASN A 1 224 ? -35.488 23.806  22.436 1.00 11.25 ?  190  ASN A N    1 
ATOM   2761  C CA   . ASN A 1 224 ? -35.512 23.538  21.007 1.00 10.67 ?  190  ASN A CA   1 
ATOM   2762  C C    . ASN A 1 224 ? -34.106 23.552  20.415 1.00 11.09 ?  190  ASN A C    1 
ATOM   2763  O O    . ASN A 1 224 ? -33.764 22.684  19.607 1.00 10.46 ?  190  ASN A O    1 
ATOM   2764  C CB   . ASN A 1 224 ? -36.431 24.526  20.287 1.00 12.52 ?  190  ASN A CB   1 
ATOM   2765  C CG   . ASN A 1 224 ? -37.896 24.216  20.517 1.00 19.02 ?  190  ASN A CG   1 
ATOM   2766  O OD1  . ASN A 1 224 ? -38.328 23.078  20.375 1.00 26.63 ?  190  ASN A OD1  1 
ATOM   2767  N ND2  . ASN A 1 224 ? -38.655 25.231  20.881 1.00 22.75 ?  190  ASN A ND2  1 
ATOM   2768  H H    . ASN A 1 224 ? -35.832 24.554  22.683 1.00 13.50 ?  190  ASN A H    1 
ATOM   2769  H HA   . ASN A 1 224 ? -35.880 22.653  20.864 1.00 12.80 ?  190  ASN A HA   1 
ATOM   2770  H HB2  . ASN A 1 224 ? -36.256 25.421  20.617 1.00 15.02 ?  190  ASN A HB2  1 
ATOM   2771  H HB3  . ASN A 1 224 ? -36.259 24.484  19.333 1.00 15.02 ?  190  ASN A HB3  1 
ATOM   2772  H HD21 . ASN A 1 224 ? -38.311 26.013  20.974 1.00 27.30 ?  190  ASN A HD21 1 
ATOM   2773  H HD22 . ASN A 1 224 ? -39.495 25.110  21.024 1.00 27.30 ?  190  ASN A HD22 1 
ATOM   2774  N N    . LYS A 1 225 ? -33.278 24.512  20.818 1.00 10.43 ?  191  LYS A N    1 
ATOM   2775  C CA   . LYS A 1 225 ? -31.912 24.564  20.302 1.00 9.70  ?  191  LYS A CA   1 
ATOM   2776  C C    . LYS A 1 225 ? -31.123 23.326  20.725 1.00 9.74  ?  191  LYS A C    1 
ATOM   2777  O O    . LYS A 1 225 ? -30.321 22.802  19.944 1.00 10.38 ?  191  LYS A O    1 
ATOM   2778  C CB   . LYS A 1 225 ? -31.212 25.849  20.730 1.00 10.83 ?  191  LYS A CB   1 
ATOM   2779  C CG   . LYS A 1 225 ? -29.876 26.104  20.053 1.00 10.24 ?  191  LYS A CG   1 
ATOM   2780  C CD   . LYS A 1 225 ? -30.028 26.476  18.579 1.00 10.66 ?  191  LYS A CD   1 
ATOM   2781  C CE   . LYS A 1 225 ? -28.698 26.878  17.979 1.00 11.35 ?  191  LYS A CE   1 
ATOM   2782  N NZ   . LYS A 1 225 ? -28.848 27.396  16.573 1.00 11.15 ?  191  LYS A NZ   1 
ATOM   2783  H H    . LYS A 1 225 ? -33.476 25.134  21.378 1.00 12.52 ?  191  LYS A H    1 
ATOM   2784  H HA   . LYS A 1 225 ? -31.947 24.579  19.332 1.00 11.64 ?  191  LYS A HA   1 
ATOM   2785  H HB2  . LYS A 1 225 ? -31.791 26.599  20.523 1.00 13.00 ?  191  LYS A HB2  1 
ATOM   2786  H HB3  . LYS A 1 225 ? -31.051 25.808  21.686 1.00 13.00 ?  191  LYS A HB3  1 
ATOM   2787  H HG2  . LYS A 1 225 ? -29.427 26.837  20.503 1.00 12.29 ?  191  LYS A HG2  1 
ATOM   2788  H HG3  . LYS A 1 225 ? -29.335 25.301  20.106 1.00 12.29 ?  191  LYS A HG3  1 
ATOM   2789  H HD2  . LYS A 1 225 ? -30.369 25.713  18.087 1.00 12.79 ?  191  LYS A HD2  1 
ATOM   2790  H HD3  . LYS A 1 225 ? -30.640 27.224  18.496 1.00 12.79 ?  191  LYS A HD3  1 
ATOM   2791  H HE2  . LYS A 1 225 ? -28.303 27.579  18.520 1.00 13.62 ?  191  LYS A HE2  1 
ATOM   2792  H HE3  . LYS A 1 225 ? -28.112 26.105  17.957 1.00 13.62 ?  191  LYS A HE3  1 
ATOM   2793  H HZ1  . LYS A 1 225 ? -29.234 26.779  16.060 1.00 13.38 ?  191  LYS A HZ1  1 
ATOM   2794  H HZ2  . LYS A 1 225 ? -29.353 28.129  16.570 1.00 13.38 ?  191  LYS A HZ2  1 
ATOM   2795  H HZ3  . LYS A 1 225 ? -28.049 27.594  16.234 1.00 13.38 ?  191  LYS A HZ3  1 
ATOM   2796  N N    . GLN A 1 226 ? -31.342 22.825  21.951 1.00 8.61  ?  192  GLN A N    1 
ATOM   2797  C CA   . GLN A 1 226 ? -30.685 21.585  22.354 1.00 9.32  ?  192  GLN A CA   1 
ATOM   2798  C C    . GLN A 1 226 ? -31.051 20.445  21.423 1.00 10.58 ?  192  GLN A C    1 
ATOM   2799  O O    . GLN A 1 226 ? -30.189 19.646  21.043 1.00 9.38  ?  192  GLN A O    1 
ATOM   2800  C CB   . GLN A 1 226 ? -31.034 21.195  23.788 1.00 9.92  ?  192  GLN A CB   1 
ATOM   2801  C CG   . GLN A 1 226 ? -30.204 20.003  24.329 1.00 9.66  ?  192  GLN A CG   1 
ATOM   2802  C CD   . GLN A 1 226 ? -30.723 18.656  23.913 1.00 10.08 ?  192  GLN A CD   1 
ATOM   2803  O OE1  . GLN A 1 226 ? -31.920 18.480  23.651 1.00 11.11 ?  192  GLN A OE1  1 
ATOM   2804  N NE2  . GLN A 1 226 ? -29.834 17.682  23.835 1.00 10.65 ?  192  GLN A NE2  1 
ATOM   2805  H H    . GLN A 1 226 ? -31.852 23.178  22.547 1.00 10.33 ?  192  GLN A H    1 
ATOM   2806  H HA   . GLN A 1 226 ? -29.728 21.744  22.318 1.00 11.18 ?  192  GLN A HA   1 
ATOM   2807  H HB2  . GLN A 1 226 ? -30.871 21.957  24.367 1.00 11.91 ?  192  GLN A HB2  1 
ATOM   2808  H HB3  . GLN A 1 226 ? -31.971 20.945  23.825 1.00 11.91 ?  192  GLN A HB3  1 
ATOM   2809  H HG2  . GLN A 1 226 ? -29.295 20.083  24.001 1.00 11.59 ?  192  GLN A HG2  1 
ATOM   2810  H HG3  . GLN A 1 226 ? -30.211 20.034  25.299 1.00 11.59 ?  192  GLN A HG3  1 
ATOM   2811  H HE21 . GLN A 1 226 ? -29.008 17.837  24.019 1.00 12.79 ?  192  GLN A HE21 1 
ATOM   2812  H HE22 . GLN A 1 226 ? -30.081 16.892  23.601 1.00 12.79 ?  192  GLN A HE22 1 
ATOM   2813  N N    . ALA A 1 227 ? -32.338 20.318  21.068 1.00 9.52  ?  193  ALA A N    1 
ATOM   2814  C CA   . ALA A 1 227 ? -32.745 19.242  20.179 1.00 10.08 ?  193  ALA A CA   1 
ATOM   2815  C C    . ALA A 1 227 ? -32.121 19.402  18.800 1.00 9.47  ?  193  ALA A C    1 
ATOM   2816  O O    . ALA A 1 227 ? -31.760 18.414  18.150 1.00 10.35 ?  193  ALA A O    1 
ATOM   2817  C CB   . ALA A 1 227 ? -34.272 19.182  20.073 1.00 12.08 ?  193  ALA A CB   1 
ATOM   2818  H H    . ALA A 1 227 ? -32.976 20.833  21.327 1.00 11.43 ?  193  ALA A H    1 
ATOM   2819  H HA   . ALA A 1 227 ? -32.440 18.401  20.554 1.00 12.09 ?  193  ALA A HA   1 
ATOM   2820  H HB1  . ALA A 1 227 ? -34.519 18.458  19.476 1.00 14.50 ?  193  ALA A HB1  1 
ATOM   2821  H HB2  . ALA A 1 227 ? -34.644 19.024  20.955 1.00 14.50 ?  193  ALA A HB2  1 
ATOM   2822  H HB3  . ALA A 1 227 ? -34.598 20.026  19.723 1.00 14.50 ?  193  ALA A HB3  1 
ATOM   2823  N N    . GLU A 1 228 ? -31.982 20.641  18.344 1.00 9.12  ?  194  GLU A N    1 
ATOM   2824  C CA   . GLU A 1 228 ? -31.350 20.911  17.051 1.00 9.85  ?  194  GLU A CA   1 
ATOM   2825  C C    . GLU A 1 228 ? -29.858 20.583  17.072 1.00 9.64  ?  194  GLU A C    1 
ATOM   2826  O O    . GLU A 1 228 ? -29.329 19.994  16.118 1.00 9.30  ?  194  GLU A O    1 
ATOM   2827  C CB   . GLU A 1 228 ? -31.579 22.374  16.674 1.00 9.46  ?  194  GLU A CB   1 
ATOM   2828  C CG   . GLU A 1 228 ? -33.074 22.672  16.380 1.00 10.53 ?  194  GLU A CG   1 
ATOM   2829  C CD   . GLU A 1 228 ? -33.536 24.083  16.701 1.00 12.43 ?  194  GLU A CD   1 
ATOM   2830  O OE1  . GLU A 1 228 ? -32.729 25.007  16.839 1.00 12.11 ?  194  GLU A OE1  1 
ATOM   2831  O OE2  . GLU A 1 228 ? -34.779 24.261  16.811 1.00 15.54 ?  194  GLU A OE2  1 
ATOM   2832  H H    . GLU A 1 228 ? -32.243 21.347  18.760 1.00 10.95 ?  194  GLU A H    1 
ATOM   2833  H HA   . GLU A 1 228 ? -31.759 20.349  16.374 1.00 11.82 ?  194  GLU A HA   1 
ATOM   2834  H HB2  . GLU A 1 228 ? -31.296 22.941  17.409 1.00 11.35 ?  194  GLU A HB2  1 
ATOM   2835  H HB3  . GLU A 1 228 ? -31.066 22.583  15.878 1.00 11.35 ?  194  GLU A HB3  1 
ATOM   2836  H HG2  . GLU A 1 228 ? -33.235 22.524  15.435 1.00 12.63 ?  194  GLU A HG2  1 
ATOM   2837  H HG3  . GLU A 1 228 ? -33.616 22.064  16.907 1.00 12.63 ?  194  GLU A HG3  1 
ATOM   2838  N N    . ILE A 1 229 ? -29.169 20.937  18.163 1.00 8.09  ?  195  ILE A N    1 
ATOM   2839  C CA   . ILE A 1 229 ? -27.766 20.557  18.317 1.00 8.34  ?  195  ILE A CA   1 
ATOM   2840  C C    . ILE A 1 229 ? -27.624 19.036  18.263 1.00 9.77  ?  195  ILE A C    1 
ATOM   2841  O O    . ILE A 1 229 ? -26.747 18.505  17.570 1.00 8.74  ?  195  ILE A O    1 
ATOM   2842  C CB   . ILE A 1 229 ? -27.189 21.146  19.615 1.00 10.04 ?  195  ILE A CB   1 
ATOM   2843  C CG1  . ILE A 1 229 ? -27.043 22.650  19.493 1.00 8.73  ?  195  ILE A CG1  1 
ATOM   2844  C CG2  . ILE A 1 229 ? -25.830 20.503  19.942 1.00 8.41  ?  195  ILE A CG2  1 
ATOM   2845  C CD1  . ILE A 1 229 ? -26.868 23.355  20.868 1.00 8.83  ?  195  ILE A CD1  1 
ATOM   2846  H H    . ILE A 1 229 ? -29.489 21.392  18.819 1.00 9.70  ?  195  ILE A H    1 
ATOM   2847  H HA   . ILE A 1 229 ? -27.258 20.926  17.578 1.00 10.00 ?  195  ILE A HA   1 
ATOM   2848  H HB   . ILE A 1 229 ? -27.806 20.952  20.337 1.00 12.04 ?  195  ILE A HB   1 
ATOM   2849  H HG12 . ILE A 1 229 ? -26.262 22.848  18.953 1.00 10.48 ?  195  ILE A HG12 1 
ATOM   2850  H HG13 . ILE A 1 229 ? -27.838 23.011  19.071 1.00 10.48 ?  195  ILE A HG13 1 
ATOM   2851  H HG21 . ILE A 1 229 ? -25.452 20.942  20.720 1.00 10.09 ?  195  ILE A HG21 1 
ATOM   2852  H HG22 . ILE A 1 229 ? -25.964 19.560  20.127 1.00 10.09 ?  195  ILE A HG22 1 
ATOM   2853  H HG23 . ILE A 1 229 ? -25.238 20.610  19.181 1.00 10.09 ?  195  ILE A HG23 1 
ATOM   2854  H HD11 . ILE A 1 229 ? -26.744 24.306  20.722 1.00 10.59 ?  195  ILE A HD11 1 
ATOM   2855  H HD12 . ILE A 1 229 ? -27.662 23.203  21.404 1.00 10.59 ?  195  ILE A HD12 1 
ATOM   2856  H HD13 . ILE A 1 229 ? -26.091 22.985  21.315 1.00 10.59 ?  195  ILE A HD13 1 
ATOM   2857  N N    . GLU A 1 230 ? -28.491 18.311  18.985 1.00 8.57  ?  196  GLU A N    1 
ATOM   2858  C CA   . GLU A 1 230 ? -28.465 16.854  18.968 1.00 9.80  ?  196  GLU A CA   1 
ATOM   2859  C C    . GLU A 1 230 ? -28.686 16.296  17.571 1.00 9.62  ?  196  GLU A C    1 
ATOM   2860  O O    . GLU A 1 230 ? -27.969 15.388  17.137 1.00 9.16  ?  196  GLU A O    1 
ATOM   2861  C CB   . GLU A 1 230 ? -29.516 16.309  19.933 1.00 10.10 ?  196  GLU A CB   1 
ATOM   2862  C CG   . GLU A 1 230 ? -29.471 14.818  20.122 1.00 12.34 ?  196  GLU A CG   1 
ATOM   2863  C CD   . GLU A 1 230 ? -30.618 14.237  20.923 1.00 19.41 ?  196  GLU A CD   1 
ATOM   2864  O OE1  . GLU A 1 230 ? -31.768 14.698  20.773 1.00 26.13 ?  196  GLU A OE1  1 
ATOM   2865  O OE2  . GLU A 1 230 ? -30.364 13.300  21.693 1.00 24.14 ?  196  GLU A OE2  1 
ATOM   2866  H H    . GLU A 1 230 ? -29.103 18.644  19.490 1.00 10.29 ?  196  GLU A H    1 
ATOM   2867  H HA   . GLU A 1 230 ? -27.588 16.562  19.263 1.00 11.75 ?  196  GLU A HA   1 
ATOM   2868  H HB2  . GLU A 1 230 ? -29.380 16.719  20.801 1.00 12.12 ?  196  GLU A HB2  1 
ATOM   2869  H HB3  . GLU A 1 230 ? -30.395 16.535  19.592 1.00 12.12 ?  196  GLU A HB3  1 
ATOM   2870  H HG2  . GLU A 1 230 ? -29.485 14.397  19.248 1.00 14.80 ?  196  GLU A HG2  1 
ATOM   2871  H HG3  . GLU A 1 230 ? -28.649 14.592  20.586 1.00 14.80 ?  196  GLU A HG3  1 
ATOM   2872  N N    . ASN A 1 231 ? -29.703 16.800  16.860 1.00 9.21  ?  197  ASN A N    1 
ATOM   2873  C CA   . ASN A 1 231 ? -29.946 16.324  15.502 1.00 9.57  ?  197  ASN A CA   1 
ATOM   2874  C C    . ASN A 1 231 ? -28.701 16.485  14.634 1.00 8.19  ?  197  ASN A C    1 
ATOM   2875  O O    . ASN A 1 231 ? -28.334 15.582  13.873 1.00 8.96  ?  197  ASN A O    1 
ATOM   2876  C CB   . ASN A 1 231 ? -31.119 17.104  14.900 1.00 10.53 ?  197  ASN A CB   1 
ATOM   2877  C CG   . ASN A 1 231 ? -31.382 16.755  13.450 1.00 15.26 ?  197  ASN A CG   1 
ATOM   2878  O OD1  . ASN A 1 231 ? -31.796 15.645  13.127 1.00 16.51 ?  197  ASN A OD1  1 
ATOM   2879  N ND2  . ASN A 1 231 ? -31.088 17.695  12.565 1.00 15.88 ?  197  ASN A ND2  1 
ATOM   2880  H H    . ASN A 1 231 ? -30.250 17.404  17.137 1.00 11.05 ?  197  ASN A H    1 
ATOM   2881  H HA   . ASN A 1 231 ? -30.175 15.382  15.529 1.00 11.48 ?  197  ASN A HA   1 
ATOM   2882  H HB2  . ASN A 1 231 ? -31.922 16.905  15.406 1.00 12.63 ?  197  ASN A HB2  1 
ATOM   2883  H HB3  . ASN A 1 231 ? -30.924 18.053  14.948 1.00 12.63 ?  197  ASN A HB3  1 
ATOM   2884  H HD21 . ASN A 1 231 ? -30.768 18.449  12.828 1.00 19.06 ?  197  ASN A HD21 1 
ATOM   2885  H HD22 . ASN A 1 231 ? -31.218 17.552  11.727 1.00 19.06 ?  197  ASN A HD22 1 
ATOM   2886  N N    . SER A 1 232 ? -28.058 17.642  14.708 1.00 9.23  ?  198  SER A N    1 
ATOM   2887  C CA   . SER A 1 232 ? -26.887 17.885  13.878 1.00 8.22  ?  198  SER A CA   1 
ATOM   2888  C C    . SER A 1 232 ? -25.713 17.013  14.305 1.00 10.42 ?  198  SER A C    1 
ATOM   2889  O O    . SER A 1 232 ? -24.929 16.566  13.459 1.00 9.73  ?  198  SER A O    1 
ATOM   2890  C CB   . SER A 1 232 ? -26.514 19.355  13.948 1.00 10.02 ?  198  SER A CB   1 
ATOM   2891  O OG   . SER A 1 232 ? -27.542 20.173  13.407 1.00 9.93  ?  198  SER A OG   1 
ATOM   2892  H H    . SER A 1 232 ? -28.274 18.295  15.224 1.00 11.08 ?  198  SER A H    1 
ATOM   2893  H HA   . SER A 1 232 ? -27.099 17.665  12.957 1.00 9.87  ?  198  SER A HA   1 
ATOM   2894  H HB2  . SER A 1 232 ? -26.373 19.599  14.876 1.00 12.03 ?  198  SER A HB2  1 
ATOM   2895  H HB3  . SER A 1 232 ? -25.699 19.497  13.441 1.00 12.03 ?  198  SER A HB3  1 
ATOM   2896  H HG   . SER A 1 232 ? -27.804 19.858  12.674 1.00 11.91 ?  198  SER A HG   1 
ATOM   2897  N N    . TYR A 1 233 ? -25.564 16.784  15.614 1.00 8.02  ?  199  TYR A N    1 
ATOM   2898  C CA   . TYR A 1 233 ? -24.549 15.871  16.119 1.00 8.76  ?  199  TYR A CA   1 
ATOM   2899  C C    . TYR A 1 233 ? -24.696 14.500  15.480 1.00 8.64  ?  199  TYR A C    1 
ATOM   2900  O O    . TYR A 1 233 ? -23.722 13.925  14.992 1.00 8.70  ?  199  TYR A O    1 
ATOM   2901  C CB   . TYR A 1 233 ? -24.643 15.796  17.653 1.00 8.78  ?  199  TYR A CB   1 
ATOM   2902  C CG   . TYR A 1 233 ? -23.943 14.590  18.244 1.00 8.44  ?  199  TYR A CG   1 
ATOM   2903  C CD1  . TYR A 1 233 ? -22.572 14.616  18.485 1.00 9.38  ?  199  TYR A CD1  1 
ATOM   2904  C CD2  . TYR A 1 233 ? -24.638 13.438  18.536 1.00 9.32  ?  199  TYR A CD2  1 
ATOM   2905  C CE1  . TYR A 1 233 ? -21.928 13.526  19.023 1.00 10.51 ?  199  TYR A CE1  1 
ATOM   2906  C CE2  . TYR A 1 233 ? -23.993 12.333  19.058 1.00 9.83  ?  199  TYR A CE2  1 
ATOM   2907  C CZ   . TYR A 1 233 ? -22.634 12.394  19.289 1.00 10.04 ?  199  TYR A CZ   1 
ATOM   2908  O OH   . TYR A 1 233 ? -22.028 11.255  19.796 1.00 12.77 ?  199  TYR A OH   1 
ATOM   2909  H H    . TYR A 1 233 ? -26.043 17.148  16.230 1.00 9.63  ?  199  TYR A H    1 
ATOM   2910  H HA   . TYR A 1 233 ? -23.666 16.204  15.895 1.00 10.51 ?  199  TYR A HA   1 
ATOM   2911  H HB2  . TYR A 1 233 ? -24.234 16.590  18.031 1.00 10.54 ?  199  TYR A HB2  1 
ATOM   2912  H HB3  . TYR A 1 233 ? -25.578 15.750  17.908 1.00 10.54 ?  199  TYR A HB3  1 
ATOM   2913  H HD1  . TYR A 1 233 ? -22.085 15.381  18.280 1.00 11.26 ?  199  TYR A HD1  1 
ATOM   2914  H HD2  . TYR A 1 233 ? -25.554 13.403  18.379 1.00 11.19 ?  199  TYR A HD2  1 
ATOM   2915  H HE1  . TYR A 1 233 ? -21.016 13.564  19.204 1.00 12.62 ?  199  TYR A HE1  1 
ATOM   2916  H HE2  . TYR A 1 233 ? -24.469 11.558  19.252 1.00 11.80 ?  199  TYR A HE2  1 
ATOM   2917  H HH   . TYR A 1 233 ? -21.435 10.985  19.266 1.00 15.33 ?  199  TYR A HH   1 
ATOM   2918  N N    . PHE A 1 234 ? -25.915 13.955  15.456 1.00 8.47  ?  200  PHE A N    1 
ATOM   2919  C CA   . PHE A 1 234 ? -26.099 12.631  14.868 1.00 8.39  ?  200  PHE A CA   1 
ATOM   2920  C C    . PHE A 1 234 ? -25.732 12.633  13.388 1.00 8.40  ?  200  PHE A C    1 
ATOM   2921  O O    . PHE A 1 234 ? -25.117 11.682  12.903 1.00 10.10 ?  200  PHE A O    1 
ATOM   2922  C CB   . PHE A 1 234 ? -27.537 12.143  15.028 1.00 10.01 ?  200  PHE A CB   1 
ATOM   2923  C CG   . PHE A 1 234 ? -27.925 11.785  16.432 1.00 10.92 ?  200  PHE A CG   1 
ATOM   2924  C CD1  . PHE A 1 234 ? -27.109 11.026  17.248 1.00 13.25 ?  200  PHE A CD1  1 
ATOM   2925  C CD2  . PHE A 1 234 ? -29.161 12.197  16.913 1.00 13.73 ?  200  PHE A CD2  1 
ATOM   2926  C CE1  . PHE A 1 234 ? -27.521 10.706  18.556 1.00 14.50 ?  200  PHE A CE1  1 
ATOM   2927  C CE2  . PHE A 1 234 ? -29.571 11.867  18.183 1.00 16.87 ?  200  PHE A CE2  1 
ATOM   2928  C CZ   . PHE A 1 234 ? -28.755 11.148  19.005 1.00 14.69 ?  200  PHE A CZ   1 
ATOM   2929  H H    . PHE A 1 234 ? -26.630 14.321  15.765 1.00 10.16 ?  200  PHE A H    1 
ATOM   2930  H HA   . PHE A 1 234 ? -25.519 12.018  15.346 1.00 10.07 ?  200  PHE A HA   1 
ATOM   2931  H HB2  . PHE A 1 234 ? -28.136 12.845  14.729 1.00 12.01 ?  200  PHE A HB2  1 
ATOM   2932  H HB3  . PHE A 1 234 ? -27.656 11.350  14.481 1.00 12.01 ?  200  PHE A HB3  1 
ATOM   2933  H HD1  . PHE A 1 234 ? -26.286 10.727  16.933 1.00 15.90 ?  200  PHE A HD1  1 
ATOM   2934  H HD2  . PHE A 1 234 ? -29.719 12.703  16.368 1.00 16.47 ?  200  PHE A HD2  1 
ATOM   2935  H HE1  . PHE A 1 234 ? -26.970 10.204  19.112 1.00 17.40 ?  200  PHE A HE1  1 
ATOM   2936  H HE2  . PHE A 1 234 ? -30.409 12.136  18.484 1.00 20.25 ?  200  PHE A HE2  1 
ATOM   2937  H HZ   . PHE A 1 234 ? -29.028 10.952  19.872 1.00 17.63 ?  200  PHE A HZ   1 
ATOM   2938  N N    . SER A 1 235 ? -26.104 13.685  12.653 1.00 9.45  ?  201  SER A N    1 
ATOM   2939  C CA   . SER A 1 235 ? -25.734 13.797  11.240 1.00 10.77 ?  201  SER A CA   1 
ATOM   2940  C C    . SER A 1 235 ? -24.222 13.791  11.064 1.00 11.07 ?  201  SER A C    1 
ATOM   2941  O O    . SER A 1 235 ? -23.687 13.122  10.178 1.00 11.10 ?  201  SER A O    1 
ATOM   2942  C CB   . SER A 1 235 ? -26.326 15.097  10.682 1.00 14.80 ?  201  SER A CB   1 
ATOM   2943  O OG   . SER A 1 235 ? -26.033 15.283  9.308  1.00 17.95 ?  201  SER A OG   1 
ATOM   2944  H H    . SER A 1 235 ? -26.570 14.345  12.947 1.00 11.34 ?  201  SER A H    1 
ATOM   2945  H HA   . SER A 1 235 ? -26.092 13.042  10.748 1.00 12.93 ?  201  SER A HA   1 
ATOM   2946  H HB2  . SER A 1 235 ? -27.290 15.069  10.791 1.00 17.76 ?  201  SER A HB2  1 
ATOM   2947  H HB3  . SER A 1 235 ? -25.958 15.844  11.180 1.00 17.76 ?  201  SER A HB3  1 
ATOM   2948  H HG   . SER A 1 235 ? -25.217 15.453  9.208  1.00 21.54 ?  201  SER A HG   1 
ATOM   2949  N N    . MET A 1 236 ? -23.513 14.523  11.914 1.00 9.05  ?  202  MET A N    1 
ATOM   2950  C CA   . MET A 1 236 ? -22.065 14.643  11.803 1.00 8.30  ?  202  MET A CA   1 
ATOM   2951  C C    . MET A 1 236 ? -21.405 13.313  12.144 1.00 9.10  ?  202  MET A C    1 
ATOM   2952  O O    . MET A 1 236 ? -20.455 12.900  11.460 1.00 9.87  ?  202  MET A O    1 
ATOM   2953  C CB   . MET A 1 236 ? -21.743 15.715  12.834 1.00 10.91 ?  202  MET A CB   1 
ATOM   2954  C CG   . MET A 1 236 ? -21.871 17.137  12.298 1.00 8.87  ?  202  MET A CG   1 
ATOM   2955  S SD   . MET A 1 236 ? -21.802 18.364  13.629 1.00 11.58 ?  202  MET A SD   1 
ATOM   2956  C CE   . MET A 1 236 ? -19.999 18.540  13.587 1.00 13.32 ?  202  MET A CE   1 
ATOM   2957  H H    . MET A 1 236 ? -23.848 14.965  12.571 1.00 10.86 ?  202  MET A H    1 
ATOM   2958  H HA   . MET A 1 236 ? -21.747 14.890  10.921 1.00 9.96  ?  202  MET A HA   1 
ATOM   2959  H HB2  . MET A 1 236 ? -22.354 15.624  13.582 1.00 13.09 ?  202  MET A HB2  1 
ATOM   2960  H HB3  . MET A 1 236 ? -20.829 15.593  13.136 1.00 13.09 ?  202  MET A HB3  1 
ATOM   2961  H HG2  . MET A 1 236 ? -21.142 17.314  11.683 1.00 10.64 ?  202  MET A HG2  1 
ATOM   2962  H HG3  . MET A 1 236 ? -22.721 17.231  11.841 1.00 10.64 ?  202  MET A HG3  1 
ATOM   2963  H HE1  . MET A 1 236 ? -19.734 19.232  14.212 1.00 15.98 ?  202  MET A HE1  1 
ATOM   2964  H HE2  . MET A 1 236 ? -19.593 17.695  13.838 1.00 15.98 ?  202  MET A HE2  1 
ATOM   2965  H HE3  . MET A 1 236 ? -19.726 18.783  12.688 1.00 15.98 ?  202  MET A HE3  1 
ATOM   2966  N N    . MET A 1 237 ? -21.881 12.623  13.176 1.00 9.44  ?  203  MET A N    1 
ATOM   2967  C CA   . MET A 1 237 ? -21.360 11.295  13.455 1.00 8.50  ?  203  MET A CA   1 
ATOM   2968  C C    . MET A 1 237 ? -21.603 10.294  12.355 1.00 10.69 ?  203  MET A C    1 
ATOM   2969  O O    . MET A 1 237 ? -20.753 9.445   12.079 1.00 10.42 ?  203  MET A O    1 
ATOM   2970  C CB   . MET A 1 237 ? -21.763 10.782  14.816 1.00 9.50  ?  203  MET A CB   1 
ATOM   2971  C CG   . MET A 1 237 ? -21.527 11.590  16.104 1.00 9.44  ?  203  MET A CG   1 
ATOM   2972  S SD   . MET A 1 237 ? -19.731 11.990  16.289 1.00 9.82  ?  203  MET A SD   1 
ATOM   2973  C CE   . MET A 1 237 ? -19.618 13.543  15.361 1.00 11.22 ?  203  MET A CE   1 
ATOM   2974  H H    . MET A 1 237 ? -22.492 12.896  13.717 1.00 11.33 ?  203  MET A H    1 
ATOM   2975  H HA   . MET A 1 237 ? -20.398 11.405  13.505 1.00 10.20 ?  203  MET A HA   1 
ATOM   2976  H HB2  . MET A 1 237 ? -22.720 10.625  14.781 1.00 11.40 ?  203  MET A HB2  1 
ATOM   2977  H HB3  . MET A 1 237 ? -21.294 9.944   14.947 1.00 11.40 ?  203  MET A HB3  1 
ATOM   2978  H HG2  . MET A 1 237 ? -22.028 12.420  16.064 1.00 11.32 ?  203  MET A HG2  1 
ATOM   2979  H HG3  . MET A 1 237 ? -21.810 11.068  16.872 1.00 11.32 ?  203  MET A HG3  1 
ATOM   2980  H HE1  . MET A 1 237 ? -18.711 13.882  15.422 1.00 13.46 ?  203  MET A HE1  1 
ATOM   2981  H HE2  . MET A 1 237 ? -19.847 13.374  14.434 1.00 13.46 ?  203  MET A HE2  1 
ATOM   2982  H HE3  . MET A 1 237 ? -20.238 14.184  15.743 1.00 13.46 ?  203  MET A HE3  1 
ATOM   2983  N N    . SER A 1 238 ? -22.773 10.360  11.722 1.00 9.29  ?  204  SER A N    1 
ATOM   2984  C CA   . SER A 1 238 ? -23.038 9.500   10.574 1.00 10.48 ?  204  SER A CA   1 
ATOM   2985  C C    . SER A 1 238 ? -22.042 9.784   9.466  1.00 9.92  ?  204  SER A C    1 
ATOM   2986  O O    . SER A 1 238 ? -21.538 8.857   8.823  1.00 11.06 ?  204  SER A O    1 
ATOM   2987  C CB   . SER A 1 238 ? -24.457 9.766   10.081 1.00 13.15 ?  204  SER A CB   1 
ATOM   2988  O OG   . SER A 1 238 ? -25.378 9.060   10.878 1.00 22.60 ?  204  SER A OG   1 
ATOM   2989  H H    . SER A 1 238 ? -23.420 10.885  11.935 1.00 11.15 ?  204  SER A H    1 
ATOM   2990  H HA   . SER A 1 238 ? -22.960 8.567   10.829 1.00 12.58 ?  204  SER A HA   1 
ATOM   2991  H HB2  . SER A 1 238 ? -24.644 10.716  10.141 1.00 15.78 ?  204  SER A HB2  1 
ATOM   2992  H HB3  . SER A 1 238 ? -24.537 9.470   9.161  1.00 15.78 ?  204  SER A HB3  1 
ATOM   2993  H HG   . SER A 1 238 ? -26.161 9.205   10.609 1.00 27.12 ?  204  SER A HG   1 
ATOM   2994  N N    . ARG A 1 239 ? -21.739 11.055  9.228  1.00 9.67  ?  205  ARG A N    1 
ATOM   2995  C CA   . ARG A 1 239 ? -20.762 11.399  8.204  1.00 10.87 ?  205  ARG A CA   1 
ATOM   2996  C C    . ARG A 1 239 ? -19.400 10.794  8.519  1.00 11.05 ?  205  ARG A C    1 
ATOM   2997  O O    . ARG A 1 239 ? -18.749 10.209  7.644  1.00 11.03 ?  205  ARG A O    1 
ATOM   2998  C CB   . ARG A 1 239 ? -20.634 12.914  8.071  1.00 12.64 ?  205  ARG A CB   1 
ATOM   2999  C CG   . ARG A 1 239 ? -21.807 13.602  7.381  1.00 15.36 ?  205  ARG A CG   1 
ATOM   3000  C CD   . ARG A 1 239 ? -21.669 13.608  5.852  1.00 16.14 ?  205  ARG A CD   1 
ATOM   3001  N NE   . ARG A 1 239 ? -20.580 14.450  5.380  1.00 13.36 ?  205  ARG A NE   1 
ATOM   3002  C CZ   . ARG A 1 239 ? -20.667 15.761  5.212  1.00 13.05 ?  205  ARG A CZ   1 
ATOM   3003  N NH1  . ARG A 1 239 ? -21.779 16.420  5.482  1.00 13.68 ?  205  ARG A NH1  1 
ATOM   3004  N NH2  . ARG A 1 239 ? -19.605 16.425  4.790  1.00 13.60 ?  205  ARG A NH2  1 
ATOM   3005  H H    . ARG A 1 239 ? -22.079 11.729  9.641  1.00 11.60 ?  205  ARG A H    1 
ATOM   3006  H HA   . ARG A 1 239 ? -21.076 11.042  7.358  1.00 13.04 ?  205  ARG A HA   1 
ATOM   3007  H HB2  . ARG A 1 239 ? -20.556 13.295  8.960  1.00 15.17 ?  205  ARG A HB2  1 
ATOM   3008  H HB3  . ARG A 1 239 ? -19.837 13.111  7.555  1.00 15.17 ?  205  ARG A HB3  1 
ATOM   3009  H HG2  . ARG A 1 239 ? -22.627 13.135  7.607  1.00 18.43 ?  205  ARG A HG2  1 
ATOM   3010  H HG3  . ARG A 1 239 ? -21.857 14.523  7.681  1.00 18.43 ?  205  ARG A HG3  1 
ATOM   3011  H HD2  . ARG A 1 239 ? -21.500 12.702  5.548  1.00 19.37 ?  205  ARG A HD2  1 
ATOM   3012  H HD3  . ARG A 1 239 ? -22.493 13.939  5.463  1.00 19.37 ?  205  ARG A HD3  1 
ATOM   3013  H HE   . ARG A 1 239 ? -19.830 14.071  5.197  1.00 16.03 ?  205  ARG A HE   1 
ATOM   3014  H HH11 . ARG A 1 239 ? -22.469 15.998  5.774  1.00 16.41 ?  205  ARG A HH11 1 
ATOM   3015  H HH12 . ARG A 1 239 ? -21.813 17.272  5.366  1.00 16.41 ?  205  ARG A HH12 1 
ATOM   3016  H HH21 . ARG A 1 239 ? -18.872 16.006  4.628  1.00 16.32 ?  205  ARG A HH21 1 
ATOM   3017  H HH22 . ARG A 1 239 ? -19.647 17.277  4.677  1.00 16.32 ?  205  ARG A HH22 1 
ATOM   3018  N N    . LEU A 1 240 ? -18.933 10.933  9.770  1.00 9.38  ?  206  LEU A N    1 
ATOM   3019  C CA   . LEU A 1 240 ? -17.624 10.383  10.124 1.00 10.03 ?  206  LEU A CA   1 
ATOM   3020  C C    . LEU A 1 240 ? -17.614 8.863   10.086 1.00 9.95  ?  206  LEU A C    1 
ATOM   3021  O O    . LEU A 1 240 ? -16.614 8.257   9.693  1.00 9.78  ?  206  LEU A O    1 
ATOM   3022  C CB   . LEU A 1 240 ? -17.191 10.834  11.516 1.00 10.63 ?  206  LEU A CB   1 
ATOM   3023  C CG   . LEU A 1 240 ? -16.803 12.296  11.677 1.00 11.13 ?  206  LEU A CG   1 
ATOM   3024  C CD1  . LEU A 1 240 ? -16.296 12.496  13.118 1.00 12.24 ?  206  LEU A CD1  1 
ATOM   3025  C CD2  . LEU A 1 240 ? -15.765 12.750  10.679 1.00 11.16 ?  206  LEU A CD2  1 
ATOM   3026  H H    A LEU A 1 240 ? -19.346 11.330  10.411 0.29 11.26 ?  206  LEU A H    1 
ATOM   3027  H H    B LEU A 1 240 ? -19.346 11.330  10.411 0.71 11.26 ?  206  LEU A H    1 
ATOM   3028  H HA   . LEU A 1 240 ? -16.993 10.725  9.472  1.00 12.04 ?  206  LEU A HA   1 
ATOM   3029  H HB2  . LEU A 1 240 ? -17.927 10.668  12.126 1.00 12.76 ?  206  LEU A HB2  1 
ATOM   3030  H HB3  . LEU A 1 240 ? -16.420 10.306  11.775 1.00 12.76 ?  206  LEU A HB3  1 
ATOM   3031  H HG   . LEU A 1 240 ? -17.580 12.850  11.506 1.00 13.35 ?  206  LEU A HG   1 
ATOM   3032  H HD11 . LEU A 1 240 ? -16.012 13.417  13.229 1.00 14.68 ?  206  LEU A HD11 1 
ATOM   3033  H HD12 . LEU A 1 240 ? -17.015 12.295  13.737 1.00 14.68 ?  206  LEU A HD12 1 
ATOM   3034  H HD13 . LEU A 1 240 ? -15.548 11.898  13.276 1.00 14.68 ?  206  LEU A HD13 1 
ATOM   3035  H HD21 . LEU A 1 240 ? -15.474 13.646  10.911 1.00 13.40 ?  206  LEU A HD21 1 
ATOM   3036  H HD22 . LEU A 1 240 ? -15.011 12.140  10.707 1.00 13.40 ?  206  LEU A HD22 1 
ATOM   3037  H HD23 . LEU A 1 240 ? -16.158 12.750  9.792  1.00 13.40 ?  206  LEU A HD23 1 
ATOM   3038  N N    . LYS A 1 241 ? -18.703 8.218   10.519 1.00 9.71  ?  207  LYS A N    1 
ATOM   3039  C CA   . LYS A 1 241 ? -18.730 6.756   10.489 1.00 9.06  ?  207  LYS A CA   1 
ATOM   3040  C C    . LYS A 1 241 ? -18.435 6.247   9.087  1.00 10.43 ?  207  LYS A C    1 
ATOM   3041  O O    . LYS A 1 241 ? -17.741 5.239   8.914  1.00 12.36 ?  207  LYS A O    1 
ATOM   3042  C CB   . LYS A 1 241 ? -20.093 6.258   10.972 1.00 11.32 ?  207  LYS A CB   1 
ATOM   3043  C CG   . LYS A 1 241 ? -20.239 4.726   11.013 1.00 12.59 ?  207  LYS A CG   1 
ATOM   3044  C CD   . LYS A 1 241 ? -21.602 4.297   11.510 1.00 12.76 ?  207  LYS A CD   1 
ATOM   3045  C CE   . LYS A 1 241 ? -21.727 2.776   11.538 1.00 16.66 ?  207  LYS A CE   1 
ATOM   3046  N NZ   . LYS A 1 241 ? -23.012 2.401   12.189 1.00 17.78 ?  207  LYS A NZ   1 
ATOM   3047  H H    . LYS A 1 241 ? -19.414 8.592   10.824 1.00 11.65 ?  207  LYS A H    1 
ATOM   3048  H HA   . LYS A 1 241 ? -18.054 6.404   11.089 1.00 10.87 ?  207  LYS A HA   1 
ATOM   3049  H HB2  . LYS A 1 241 ? -20.242 6.590   11.871 1.00 13.59 ?  207  LYS A HB2  1 
ATOM   3050  H HB3  . LYS A 1 241 ? -20.776 6.601   10.374 1.00 13.59 ?  207  LYS A HB3  1 
ATOM   3051  H HG2  . LYS A 1 241 ? -20.118 4.370   10.119 1.00 15.11 ?  207  LYS A HG2  1 
ATOM   3052  H HG3  . LYS A 1 241 ? -19.569 4.358   11.610 1.00 15.11 ?  207  LYS A HG3  1 
ATOM   3053  H HD2  . LYS A 1 241 ? -21.736 4.631   12.411 1.00 15.32 ?  207  LYS A HD2  1 
ATOM   3054  H HD3  . LYS A 1 241 ? -22.286 4.649   10.920 1.00 15.32 ?  207  LYS A HD3  1 
ATOM   3055  H HE2  . LYS A 1 241 ? -21.720 2.429   10.632 1.00 19.99 ?  207  LYS A HE2  1 
ATOM   3056  H HE3  . LYS A 1 241 ? -20.994 2.394   12.046 1.00 19.99 ?  207  LYS A HE3  1 
ATOM   3057  H HZ1  . LYS A 1 241 ? -23.061 2.765   12.999 1.00 21.34 ?  207  LYS A HZ1  1 
ATOM   3058  H HZ2  . LYS A 1 241 ? -23.697 2.690   11.700 1.00 21.34 ?  207  LYS A HZ2  1 
ATOM   3059  H HZ3  . LYS A 1 241 ? -23.066 1.516   12.266 1.00 21.34 ?  207  LYS A HZ3  1 
ATOM   3060  N N    . GLU A 1 242 ? -18.942 6.938   8.074  1.00 10.87 ?  208  GLU A N    1 
ATOM   3061  C CA   . GLU A 1 242 ? -18.679 6.575   6.686  1.00 11.85 ?  208  GLU A CA   1 
ATOM   3062  C C    . GLU A 1 242 ? -17.284 7.008   6.234  1.00 12.54 ?  208  GLU A C    1 
ATOM   3063  O O    . GLU A 1 242 ? -16.534 6.206   5.667  1.00 13.10 ?  208  GLU A O    1 
ATOM   3064  C CB   . GLU A 1 242 ? -19.754 7.191   5.789  1.00 15.17 ?  208  GLU A CB   1 
ATOM   3065  C CG   . GLU A 1 242 ? -19.799 6.648   4.375  1.00 29.38 ?  208  GLU A CG   1 
ATOM   3066  C CD   . GLU A 1 242 ? -19.962 5.144   4.354  1.00 35.45 ?  208  GLU A CD   1 
ATOM   3067  O OE1  . GLU A 1 242 ? -19.059 4.453   3.834  1.00 43.36 ?  208  GLU A OE1  1 
ATOM   3068  O OE2  . GLU A 1 242 ? -20.975 4.652   4.891  1.00 46.04 ?  208  GLU A OE2  1 
ATOM   3069  H H    . GLU A 1 242 ? -19.447 7.628   8.162  1.00 13.04 ?  208  GLU A H    1 
ATOM   3070  H HA   . GLU A 1 242 ? -18.720 5.610   6.601  1.00 14.22 ?  208  GLU A HA   1 
ATOM   3071  H HB2  . GLU A 1 242 ? -20.621 7.025   6.191  1.00 18.20 ?  208  GLU A HB2  1 
ATOM   3072  H HB3  . GLU A 1 242 ? -19.594 8.146   5.728  1.00 18.20 ?  208  GLU A HB3  1 
ATOM   3073  H HG2  . GLU A 1 242 ? -20.551 7.041   3.905  1.00 35.26 ?  208  GLU A HG2  1 
ATOM   3074  H HG3  . GLU A 1 242 ? -18.971 6.870   3.921  1.00 35.26 ?  208  GLU A HG3  1 
ATOM   3075  N N    . SER A 1 243 ? -16.911 8.267   6.444  1.00 10.56 ?  209  SER A N    1 
ATOM   3076  C CA   . SER A 1 243 ? -15.656 8.735   5.865  1.00 10.72 ?  209  SER A CA   1 
ATOM   3077  C C    . SER A 1 243 ? -14.443 8.144   6.566  1.00 12.35 ?  209  SER A C    1 
ATOM   3078  O O    . SER A 1 243 ? -13.380 7.995   5.944  1.00 12.45 ?  209  SER A O    1 
ATOM   3079  C CB   . SER A 1 243 ? -15.570 10.250  5.899  1.00 11.85 ?  209  SER A CB   1 
ATOM   3080  O OG   . SER A 1 243 ? -15.592 10.703  7.239  1.00 12.41 ?  209  SER A OG   1 
ATOM   3081  H H    . SER A 1 243 ? -17.350 8.849   6.899  1.00 12.67 ?  209  SER A H    1 
ATOM   3082  H HA   . SER A 1 243 ? -15.644 8.452   4.937  1.00 12.86 ?  209  SER A HA   1 
ATOM   3083  H HB2  . SER A 1 243 ? -14.743 10.533  5.480  1.00 14.22 ?  209  SER A HB2  1 
ATOM   3084  H HB3  . SER A 1 243 ? -16.328 10.624  5.423  1.00 14.22 ?  209  SER A HB3  1 
ATOM   3085  H HG   . SER A 1 243 ? -15.844 11.504  7.267  1.00 14.89 ?  209  SER A HG   1 
ATOM   3086  N N    . LEU A 1 244 ? -14.573 7.795   7.844  1.00 10.25 ?  210  LEU A N    1 
ATOM   3087  C CA   . LEU A 1 244 ? -13.485 7.202   8.606  1.00 9.37  ?  210  LEU A CA   1 
ATOM   3088  C C    . LEU A 1 244 ? -13.624 5.696   8.763  1.00 9.79  ?  210  LEU A C    1 
ATOM   3089  O O    . LEU A 1 244 ? -13.025 5.108   9.669  1.00 9.94  ?  210  LEU A O    1 
ATOM   3090  C CB   . LEU A 1 244 ? -13.392 7.889   9.966  1.00 9.33  ?  210  LEU A CB   1 
ATOM   3091  C CG   . LEU A 1 244 ? -13.219 9.402   9.921  1.00 10.85 ?  210  LEU A CG   1 
ATOM   3092  C CD1  . LEU A 1 244 ? -12.929 9.933   11.324 1.00 10.32 ?  210  LEU A CD1  1 
ATOM   3093  C CD2  . LEU A 1 244 ? -12.128 9.819   8.976  1.00 12.08 ?  210  LEU A CD2  1 
ATOM   3094  H H    . LEU A 1 244 ? -15.297 7.895   8.297  1.00 12.30 ?  210  LEU A H    1 
ATOM   3095  H HA   . LEU A 1 244 ? -12.651 7.351   8.134  1.00 11.25 ?  210  LEU A HA   1 
ATOM   3096  H HB2  . LEU A 1 244 ? -14.208 7.705   10.457 1.00 11.19 ?  210  LEU A HB2  1 
ATOM   3097  H HB3  . LEU A 1 244 ? -12.629 7.524   10.441 1.00 11.19 ?  210  LEU A HB3  1 
ATOM   3098  H HG   . LEU A 1 244 ? -14.044 9.792   9.592  1.00 13.02 ?  210  LEU A HG   1 
ATOM   3099  H HD11 . LEU A 1 244 ? -12.865 10.901  11.289 1.00 12.39 ?  210  LEU A HD11 1 
ATOM   3100  H HD12 . LEU A 1 244 ? -13.651 9.671   11.916 1.00 12.39 ?  210  LEU A HD12 1 
ATOM   3101  H HD13 . LEU A 1 244 ? -12.092 9.557   11.637 1.00 12.39 ?  210  LEU A HD13 1 
ATOM   3102  H HD21 . LEU A 1 244 ? -11.999 10.777  9.045  1.00 14.49 ?  210  LEU A HD21 1 
ATOM   3103  H HD22 . LEU A 1 244 ? -11.309 9.357   9.216  1.00 14.49 ?  210  LEU A HD22 1 
ATOM   3104  H HD23 . LEU A 1 244 ? -12.387 9.584   8.071  1.00 14.49 ?  210  LEU A HD23 1 
ATOM   3105  N N    . SER A 1 245 ? -14.356 5.042   7.854  1.00 10.83 ?  211  SER A N    1 
ATOM   3106  C CA   . SER A 1 245 ? -14.558 3.604   7.962  1.00 12.15 ?  211  SER A CA   1 
ATOM   3107  C C    . SER A 1 245 ? -13.284 2.777   7.794  1.00 10.98 ?  211  SER A C    1 
ATOM   3108  O O    . SER A 1 245 ? -13.276 1.608   8.199  1.00 13.32 ?  211  SER A O    1 
ATOM   3109  C CB   . SER A 1 245 ? -15.610 3.151   6.945  1.00 13.43 ?  211  SER A CB   1 
ATOM   3110  O OG   . SER A 1 245 ? -15.129 3.313   5.630  1.00 16.81 ?  211  SER A OG   1 
ATOM   3111  H H    . SER A 1 245 ? -14.738 5.408   7.175  1.00 13.00 ?  211  SER A H    1 
ATOM   3112  H HA   . SER A 1 245 ? -14.886 3.422   8.857  1.00 14.58 ?  211  SER A HA   1 
ATOM   3113  H HB2  . SER A 1 245 ? -15.814 2.214   7.095  1.00 16.11 ?  211  SER A HB2  1 
ATOM   3114  H HB3  . SER A 1 245 ? -16.411 3.686   7.058  1.00 16.11 ?  211  SER A HB3  1 
ATOM   3115  H HG   . SER A 1 245 ? -15.627 2.907   5.090  1.00 20.17 ?  211  SER A HG   1 
ATOM   3116  N N    . ASN A 1 246 ? -12.218 3.336   7.224  1.00 10.79 ?  212  ASN A N    1 
ATOM   3117  C CA   . ASN A 1 246 ? -10.916 2.676   7.159  1.00 11.49 ?  212  ASN A CA   1 
ATOM   3118  C C    . ASN A 1 246 ? -9.957  3.190   8.223  1.00 11.85 ?  212  ASN A C    1 
ATOM   3119  O O    . ASN A 1 246 ? -8.741  2.985   8.123  1.00 13.09 ?  212  ASN A O    1 
ATOM   3120  C CB   . ASN A 1 246 ? -10.317 2.822   5.763  1.00 13.94 ?  212  ASN A CB   1 
ATOM   3121  C CG   . ASN A 1 246 ? -11.201 2.212   4.694  1.00 19.57 ?  212  ASN A CG   1 
ATOM   3122  O OD1  . ASN A 1 246 ? -11.652 1.087   4.837  1.00 20.49 ?  212  ASN A OD1  1 
ATOM   3123  N ND2  . ASN A 1 246 ? -11.469 2.968   3.629  1.00 23.86 ?  212  ASN A ND2  1 
ATOM   3124  H H    . ASN A 1 246 ? -12.225 4.115   6.859  1.00 12.95 ?  212  ASN A H    1 
ATOM   3125  H HA   . ASN A 1 246 ? -11.039 1.727   7.319  1.00 13.79 ?  212  ASN A HA   1 
ATOM   3126  H HB2  . ASN A 1 246 ? -10.206 3.764   5.561  1.00 16.73 ?  212  ASN A HB2  1 
ATOM   3127  H HB3  . ASN A 1 246 ? -9.458  2.373   5.736  1.00 16.73 ?  212  ASN A HB3  1 
ATOM   3128  H HD21 . ASN A 1 246 ? -11.966 2.661   2.999  1.00 28.63 ?  212  ASN A HD21 1 
ATOM   3129  H HD22 . ASN A 1 246 ? -11.144 3.762   3.573  1.00 28.63 ?  212  ASN A HD22 1 
ATOM   3130  N N    . ASN A 1 247 ? -10.506 3.824   9.257  1.00 9.23  ?  213  ASN A N    1 
ATOM   3131  C CA   . ASN A 1 247 ? -9.763  4.430   10.354 1.00 9.36  ?  213  ASN A CA   1 
ATOM   3132  C C    . ASN A 1 247 ? -10.463 4.063   11.663 1.00 9.71  ?  213  ASN A C    1 
ATOM   3133  O O    . ASN A 1 247 ? -11.414 3.283   11.690 1.00 10.56 ?  213  ASN A O    1 
ATOM   3134  C CB   . ASN A 1 247 ? -9.718  5.953   10.154 1.00 9.19  ?  213  ASN A CB   1 
ATOM   3135  C CG   . ASN A 1 247 ? -8.847  6.355   8.980  1.00 10.71 ?  213  ASN A CG   1 
ATOM   3136  O OD1  . ASN A 1 247 ? -9.345  6.738   7.910  1.00 11.64 ?  213  ASN A OD1  1 
ATOM   3137  N ND2  . ASN A 1 247 ? -7.547  6.262   9.165  1.00 10.19 ?  213  ASN A ND2  1 
ATOM   3138  H H    . ASN A 1 247 ? -11.356 3.922   9.348  1.00 11.08 ?  213  ASN A H    1 
ATOM   3139  H HA   . ASN A 1 247 ? -8.863  4.068   10.371 1.00 11.23 ?  213  ASN A HA   1 
ATOM   3140  H HB2  . ASN A 1 247 ? -10.617 6.278   9.988  1.00 11.03 ?  213  ASN A HB2  1 
ATOM   3141  H HB3  . ASN A 1 247 ? -9.358  6.368   10.953 1.00 11.03 ?  213  ASN A HB3  1 
ATOM   3142  H HD21 . ASN A 1 247 ? -7.006  6.478   8.532  1.00 12.23 ?  213  ASN A HD21 1 
ATOM   3143  H HD22 . ASN A 1 247 ? -7.238  5.986   9.919  1.00 12.23 ?  213  ASN A HD22 1 
ATOM   3144  N N    . LEU A 1 248 ? -10.018 4.653   12.769 1.00 8.54  ?  214  LEU A N    1 
ATOM   3145  C CA   . LEU A 1 248 ? -10.629 4.436   14.075 1.00 9.94  ?  214  LEU A CA   1 
ATOM   3146  C C    . LEU A 1 248 ? -11.348 5.686   14.571 1.00 7.33  ?  214  LEU A C    1 
ATOM   3147  O O    . LEU A 1 248 ? -10.856 6.810   14.417 1.00 9.28  ?  214  LEU A O    1 
ATOM   3148  C CB   . LEU A 1 248 ? -9.570  4.038   15.103 1.00 9.19  ?  214  LEU A CB   1 
ATOM   3149  C CG   . LEU A 1 248 ? -8.925  2.669   14.871 1.00 9.78  ?  214  LEU A CG   1 
ATOM   3150  C CD1  . LEU A 1 248 ? -7.789  2.433   15.846 1.00 11.04 ?  214  LEU A CD1  1 
ATOM   3151  C CD2  . LEU A 1 248 ? -9.937  1.539   14.976 1.00 11.09 ?  214  LEU A CD2  1 
ATOM   3152  H H    . LEU A 1 248 ? -9.350  5.194   12.787 1.00 10.25 ?  214  LEU A H    1 
ATOM   3153  H HA   . LEU A 1 248 ? -11.288 3.730   13.990 1.00 11.93 ?  214  LEU A HA   1 
ATOM   3154  H HB2  . LEU A 1 248 ? -8.862  4.700   15.086 1.00 11.03 ?  214  LEU A HB2  1 
ATOM   3155  H HB3  . LEU A 1 248 ? -9.986  4.019   15.980 1.00 11.03 ?  214  LEU A HB3  1 
ATOM   3156  H HG   . LEU A 1 248 ? -8.569  2.664   13.969 1.00 11.74 ?  214  LEU A HG   1 
ATOM   3157  H HD11 . LEU A 1 248 ? -7.301  1.640   15.576 1.00 13.25 ?  214  LEU A HD11 1 
ATOM   3158  H HD12 . LEU A 1 248 ? -7.200  3.204   15.836 1.00 13.25 ?  214  LEU A HD12 1 
ATOM   3159  H HD13 . LEU A 1 248 ? -8.157  2.310   16.735 1.00 13.25 ?  214  LEU A HD13 1 
ATOM   3160  H HD21 . LEU A 1 248 ? -9.466  0.691   14.975 1.00 13.30 ?  214  LEU A HD21 1 
ATOM   3161  H HD22 . LEU A 1 248 ? -10.437 1.639   15.801 1.00 13.30 ?  214  LEU A HD22 1 
ATOM   3162  H HD23 . LEU A 1 248 ? -10.540 1.583   14.217 1.00 13.30 ?  214  LEU A HD23 1 
ATOM   3163  N N    . ILE A 1 249 ? -12.491 5.474   15.200 1.00 7.87  ?  215  ILE A N    1 
ATOM   3164  C CA   . ILE A 1 249 ? -13.231 6.524   15.885 1.00 7.80  ?  215  ILE A CA   1 
ATOM   3165  C C    . ILE A 1 249 ? -13.488 6.060   17.307 1.00 8.29  ?  215  ILE A C    1 
ATOM   3166  O O    . ILE A 1 249 ? -14.207 5.074   17.530 1.00 9.07  ?  215  ILE A O    1 
ATOM   3167  C CB   . ILE A 1 249 ? -14.554 6.879   15.203 1.00 9.08  ?  215  ILE A CB   1 
ATOM   3168  C CG1  . ILE A 1 249 ? -14.440 6.991   13.689 1.00 10.02 ?  215  ILE A CG1  1 
ATOM   3169  C CG2  . ILE A 1 249 ? -15.089 8.203   15.785 1.00 10.65 ?  215  ILE A CG2  1 
ATOM   3170  C CD1  . ILE A 1 249 ? -15.803 7.195   13.018 1.00 12.62 ?  215  ILE A CD1  1 
ATOM   3171  H H    . ILE A 1 249 ? -12.872 4.704   15.247 1.00 9.45  ?  215  ILE A H    1 
ATOM   3172  H HA   . ILE A 1 249 ? -12.675 7.319   15.906 1.00 9.36  ?  215  ILE A HA   1 
ATOM   3173  H HB   . ILE A 1 249 ? -15.167 6.150   15.381 1.00 10.89 ?  215  ILE A HB   1 
ATOM   3174  H HG12 . ILE A 1 249 ? -13.878 7.750   13.468 1.00 12.02 ?  215  ILE A HG12 1 
ATOM   3175  H HG13 . ILE A 1 249 ? -14.050 6.175   13.339 1.00 12.02 ?  215  ILE A HG13 1 
ATOM   3176  H HG21 . ILE A 1 249 ? -16.012 8.318   15.510 1.00 12.77 ?  215  ILE A HG21 1 
ATOM   3177  H HG22 . ILE A 1 249 ? -15.034 8.168   16.752 1.00 12.77 ?  215  ILE A HG22 1 
ATOM   3178  H HG23 . ILE A 1 249 ? -14.550 8.936   15.449 1.00 12.77 ?  215  ILE A HG23 1 
ATOM   3179  H HD11 . ILE A 1 249 ? -15.716 7.025   12.067 1.00 15.14 ?  215  ILE A HD11 1 
ATOM   3180  H HD12 . ILE A 1 249 ? -16.442 6.577   13.407 1.00 15.14 ?  215  ILE A HD12 1 
ATOM   3181  H HD13 . ILE A 1 249 ? -16.094 8.108   13.165 1.00 15.14 ?  215  ILE A HD13 1 
ATOM   3182  N N    . LEU A 1 250 ? -12.899 6.750   18.274 1.00 8.41  ?  216  LEU A N    1 
ATOM   3183  C CA   . LEU A 1 250 ? -13.129 6.496   19.686 1.00 8.29  ?  216  LEU A CA   1 
ATOM   3184  C C    . LEU A 1 250 ? -13.908 7.677   20.229 1.00 8.95  ?  216  LEU A C    1 
ATOM   3185  O O    . LEU A 1 250 ? -13.661 8.816   19.825 1.00 12.67 ?  216  LEU A O    1 
ATOM   3186  C CB   . LEU A 1 250 ? -11.797 6.399   20.412 1.00 9.71  ?  216  LEU A CB   1 
ATOM   3187  C CG   . LEU A 1 250 ? -11.744 5.758   21.781 1.00 12.80 ?  216  LEU A CG   1 
ATOM   3188  C CD1  . LEU A 1 250 ? -12.092 4.276   21.684 1.00 16.97 ?  216  LEU A CD1  1 
ATOM   3189  C CD2  . LEU A 1 250 ? -10.370 5.943   22.384 1.00 15.09 ?  216  LEU A CD2  1 
ATOM   3190  H H    . LEU A 1 250 ? -12.344 7.391   18.131 1.00 10.09 ?  216  LEU A H    1 
ATOM   3191  H HA   . LEU A 1 250 ? -13.624 5.674   19.829 1.00 9.95  ?  216  LEU A HA   1 
ATOM   3192  H HB2  . LEU A 1 250 ? -11.197 5.887   19.848 1.00 11.65 ?  216  LEU A HB2  1 
ATOM   3193  H HB3  . LEU A 1 250 ? -11.461 7.302   20.521 1.00 11.65 ?  216  LEU A HB3  1 
ATOM   3194  H HG   . LEU A 1 250 ? -12.393 6.182   22.363 1.00 15.36 ?  216  LEU A HG   1 
ATOM   3195  H HD11 . LEU A 1 250 ? -12.269 3.934   22.574 1.00 20.36 ?  216  LEU A HD11 1 
ATOM   3196  H HD12 . LEU A 1 250 ? -12.879 4.172   21.127 1.00 20.36 ?  216  LEU A HD12 1 
ATOM   3197  H HD13 . LEU A 1 250 ? -11.343 3.801   21.290 1.00 20.36 ?  216  LEU A HD13 1 
ATOM   3198  H HD21 . LEU A 1 250 ? -10.366 5.571   23.280 1.00 18.11 ?  216  LEU A HD21 1 
ATOM   3199  H HD22 . LEU A 1 250 ? -9.718  5.483   21.832 1.00 18.11 ?  216  LEU A HD22 1 
ATOM   3200  H HD23 . LEU A 1 250 ? -10.165 6.890   22.418 1.00 18.11 ?  216  LEU A HD23 1 
ATOM   3201  N N    . ALA A 1 251 ? -14.865 7.432   21.102 1.00 7.28  ?  217  ALA A N    1 
ATOM   3202  C CA   . ALA A 1 251 ? -15.674 8.517   21.653 1.00 8.02  ?  217  ALA A CA   1 
ATOM   3203  C C    . ALA A 1 251 ? -15.742 8.468   23.175 1.00 7.27  ?  217  ALA A C    1 
ATOM   3204  O O    . ALA A 1 251 ? -15.750 7.398   23.789 1.00 8.05  ?  217  ALA A O    1 
ATOM   3205  C CB   . ALA A 1 251 ? -17.104 8.474   21.136 1.00 9.77  ?  217  ALA A CB   1 
ATOM   3206  H H    . ALA A 1 251 ? -15.070 6.650   21.394 1.00 8.73  ?  217  ALA A H    1 
ATOM   3207  H HA   . ALA A 1 251 ? -15.243 9.346   21.394 1.00 9.62  ?  217  ALA A HA   1 
ATOM   3208  H HB1  . ALA A 1 251 ? -17.599 9.217   21.515 1.00 11.72 ?  217  ALA A HB1  1 
ATOM   3209  H HB2  . ALA A 1 251 ? -17.092 8.543   20.169 1.00 11.72 ?  217  ALA A HB2  1 
ATOM   3210  H HB3  . ALA A 1 251 ? -17.511 7.635   21.404 1.00 11.72 ?  217  ALA A HB3  1 
ATOM   3211  N N    . ASN A 1 252 ? -15.831 9.647   23.795 1.00 7.99  ?  218  ASN A N    1 
ATOM   3212  C CA   . ASN A 1 252 ? -16.065 9.769   25.242 1.00 7.46  ?  218  ASN A CA   1 
ATOM   3213  C C    . ASN A 1 252 ? -17.570 9.654   25.444 1.00 7.23  ?  218  ASN A C    1 
ATOM   3214  O O    . ASN A 1 252 ? -18.293 10.658  25.419 1.00 8.22  ?  218  ASN A O    1 
ATOM   3215  C CB   . ASN A 1 252 ? -15.515 11.112  25.705 1.00 7.27  ?  218  ASN A CB   1 
ATOM   3216  C CG   . ASN A 1 252 ? -15.620 11.332  27.188 1.00 6.24  ?  218  ASN A CG   1 
ATOM   3217  O OD1  . ASN A 1 252 ? -16.078 10.470  27.946 1.00 7.15  ?  218  ASN A OD1  1 
ATOM   3218  N ND2  . ASN A 1 252 ? -15.185 12.506  27.625 1.00 6.67  ?  218  ASN A ND2  1 
ATOM   3219  H H    . ASN A 1 252 ? -15.759 10.405  23.395 1.00 9.59  ?  218  ASN A H    1 
ATOM   3220  H HA   . ASN A 1 252 ? -15.633 9.064   25.750 1.00 8.95  ?  218  ASN A HA   1 
ATOM   3221  H HB2  . ASN A 1 252 ? -14.577 11.165  25.465 1.00 8.72  ?  218  ASN A HB2  1 
ATOM   3222  H HB3  . ASN A 1 252 ? -16.010 11.821  25.266 1.00 8.72  ?  218  ASN A HB3  1 
ATOM   3223  H HD21 . ASN A 1 252 ? -15.219 12.692  28.464 1.00 8.01  ?  218  ASN A HD21 1 
ATOM   3224  H HD22 . ASN A 1 252 ? -14.870 13.082  27.070 1.00 8.01  ?  218  ASN A HD22 1 
ATOM   3225  N N    . ILE A 1 253 ? -18.068 8.417   25.596 1.00 7.46  ?  219  ILE A N    1 
ATOM   3226  C CA   . ILE A 1 253 ? -19.512 8.178   25.513 1.00 8.59  ?  219  ILE A CA   1 
ATOM   3227  C C    . ILE A 1 253 ? -20.100 7.275   26.598 1.00 8.89  ?  219  ILE A C    1 
ATOM   3228  O O    . ILE A 1 253 ? -21.200 7.559   27.095 1.00 10.43 ?  219  ILE A O    1 
ATOM   3229  C CB   . ILE A 1 253 ? -19.912 7.729   24.084 1.00 9.90  ?  219  ILE A CB   1 
ATOM   3230  C CG1  . ILE A 1 253 ? -21.431 7.653   23.929 1.00 11.76 ?  219  ILE A CG1  1 
ATOM   3231  C CG2  . ILE A 1 253 ? -19.294 6.404   23.709 1.00 11.26 ?  219  ILE A CG2  1 
ATOM   3232  C CD1  . ILE A 1 253 ? -22.135 8.970   24.171 1.00 13.22 ?  219  ILE A CD1  1 
ATOM   3233  H H    . ILE A 1 253 ? -17.596 7.714   25.745 1.00 8.95  ?  219  ILE A H    1 
ATOM   3234  H HA   . ILE A 1 253 ? -19.923 9.031   25.720 1.00 10.30 ?  219  ILE A HA   1 
ATOM   3235  H HB   . ILE A 1 253 ? -19.567 8.406   23.482 1.00 11.88 ?  219  ILE A HB   1 
ATOM   3236  H HG12 . ILE A 1 253 ? -21.639 7.368   23.025 1.00 14.12 ?  219  ILE A HG12 1 
ATOM   3237  H HG13 . ILE A 1 253 ? -21.778 7.010   24.567 1.00 14.12 ?  219  ILE A HG13 1 
ATOM   3238  H HG21 . ILE A 1 253 ? -19.425 6.251   22.760 1.00 13.52 ?  219  ILE A HG21 1 
ATOM   3239  H HG22 . ILE A 1 253 ? -18.345 6.429   23.912 1.00 13.52 ?  219  ILE A HG22 1 
ATOM   3240  H HG23 . ILE A 1 253 ? -19.722 5.700   24.220 1.00 13.52 ?  219  ILE A HG23 1 
ATOM   3241  H HD11 . ILE A 1 253 ? -23.037 8.915   23.819 1.00 15.86 ?  219  ILE A HD11 1 
ATOM   3242  H HD12 . ILE A 1 253 ? -22.162 9.143   25.125 1.00 15.86 ?  219  ILE A HD12 1 
ATOM   3243  H HD13 . ILE A 1 253 ? -21.647 9.677   23.721 1.00 15.86 ?  219  ILE A HD13 1 
ATOM   3244  N N    . ILE A 1 254 ? -19.432 6.191   26.984 1.00 7.80  ?  220  ILE A N    1 
ATOM   3245  C CA   . ILE A 1 254 ? -19.995 5.347   28.038 1.00 8.72  ?  220  ILE A CA   1 
ATOM   3246  C C    . ILE A 1 254 ? -19.842 6.048   29.377 1.00 8.76  ?  220  ILE A C    1 
ATOM   3247  O O    . ILE A 1 254 ? -18.739 6.429   29.769 1.00 9.25  ?  220  ILE A O    1 
ATOM   3248  C CB   . ILE A 1 254 ? -19.336 3.966   28.064 1.00 9.72  ?  220  ILE A CB   1 
ATOM   3249  C CG1  . ILE A 1 254 ? -19.712 3.172   26.819 1.00 10.18 ?  220  ILE A CG1  1 
ATOM   3250  C CG2  . ILE A 1 254 ? -19.748 3.206   29.347 1.00 11.13 ?  220  ILE A CG2  1 
ATOM   3251  C CD1  . ILE A 1 254 ? -18.939 1.864   26.688 1.00 12.58 ?  220  ILE A CD1  1 
ATOM   3252  H H    . ILE A 1 254 ? -18.677 5.930   26.663 1.00 9.36  ?  220  ILE A H    1 
ATOM   3253  H HA   . ILE A 1 254 ? -20.938 5.219   27.854 1.00 10.46 ?  220  ILE A HA   1 
ATOM   3254  H HB   . ILE A 1 254 ? -18.373 4.082   28.068 1.00 11.66 ?  220  ILE A HB   1 
ATOM   3255  H HG12 . ILE A 1 254 ? -20.657 2.958   26.856 1.00 12.22 ?  220  ILE A HG12 1 
ATOM   3256  H HG13 . ILE A 1 254 ? -19.524 3.710   26.034 1.00 12.22 ?  220  ILE A HG13 1 
ATOM   3257  H HG21 . ILE A 1 254 ? -19.585 2.258   29.218 1.00 13.36 ?  220  ILE A HG21 1 
ATOM   3258  H HG22 . ILE A 1 254 ? -19.220 3.534   30.092 1.00 13.36 ?  220  ILE A HG22 1 
ATOM   3259  H HG23 . ILE A 1 254 ? -20.690 3.359   29.516 1.00 13.36 ?  220  ILE A HG23 1 
ATOM   3260  H HD11 . ILE A 1 254 ? -19.007 1.548   25.773 1.00 15.10 ?  220  ILE A HD11 1 
ATOM   3261  H HD12 . ILE A 1 254 ? -18.009 2.023   26.914 1.00 15.10 ?  220  ILE A HD12 1 
ATOM   3262  H HD13 . ILE A 1 254 ? -19.320 1.210   27.294 1.00 15.10 ?  220  ILE A HD13 1 
ATOM   3263  N N    . ARG A 1 255 ? -20.950 6.169   30.109 1.00 9.10  ?  221  ARG A N    1 
ATOM   3264  C CA   . ARG A 1 255 ? -21.024 6.977   31.312 1.00 8.53  ?  221  ARG A CA   1 
ATOM   3265  C C    . ARG A 1 255 ? -22.332 6.679   32.031 1.00 10.35 ?  221  ARG A C    1 
ATOM   3266  O O    . ARG A 1 255 ? -23.396 6.704   31.410 1.00 10.78 ?  221  ARG A O    1 
ATOM   3267  C CB   . ARG A 1 255 ? -20.953 8.453   30.923 1.00 10.06 ?  221  ARG A CB   1 
ATOM   3268  C CG   . ARG A 1 255 ? -20.855 9.407   32.100 1.00 10.24 ?  221  ARG A CG   1 
ATOM   3269  C CD   . ARG A 1 255 ? -19.420 9.578   32.577 1.00 10.10 ?  221  ARG A CD   1 
ATOM   3270  N NE   . ARG A 1 255 ? -18.543 10.149  31.555 1.00 8.48  ?  221  ARG A NE   1 
ATOM   3271  C CZ   . ARG A 1 255 ? -18.516 11.426  31.205 1.00 9.15  ?  221  ARG A CZ   1 
ATOM   3272  N NH1  . ARG A 1 255 ? -19.309 12.320  31.775 1.00 9.14  ?  221  ARG A NH1  1 
ATOM   3273  N NH2  . ARG A 1 255 ? -17.670 11.817  30.262 1.00 8.49  ?  221  ARG A NH2  1 
ATOM   3274  H H    . ARG A 1 255 ? -21.692 5.778   29.919 1.00 10.91 ?  221  ARG A H    1 
ATOM   3275  H HA   . ARG A 1 255 ? -20.288 6.781   31.912 1.00 10.23 ?  221  ARG A HA   1 
ATOM   3276  H HB2  . ARG A 1 255 ? -20.169 8.589   30.368 1.00 12.07 ?  221  ARG A HB2  1 
ATOM   3277  H HB3  . ARG A 1 255 ? -21.755 8.681   30.426 1.00 12.07 ?  221  ARG A HB3  1 
ATOM   3278  H HG2  . ARG A 1 255 ? -21.192 10.278  31.835 1.00 12.28 ?  221  ARG A HG2  1 
ATOM   3279  H HG3  . ARG A 1 255 ? -21.380 9.060   32.838 1.00 12.28 ?  221  ARG A HG3  1 
ATOM   3280  H HD2  . ARG A 1 255 ? -19.411 10.172  33.344 1.00 12.12 ?  221  ARG A HD2  1 
ATOM   3281  H HD3  . ARG A 1 255 ? -19.064 8.710   32.825 1.00 12.12 ?  221  ARG A HD3  1 
ATOM   3282  H HE   . ARG A 1 255 ? -18.003 9.615   31.151 1.00 10.18 ?  221  ARG A HE   1 
ATOM   3283  H HH11 . ARG A 1 255 ? -19.859 12.078  32.389 1.00 10.97 ?  221  ARG A HH11 1 
ATOM   3284  H HH12 . ARG A 1 255 ? -19.273 13.144  31.530 1.00 10.97 ?  221  ARG A HH12 1 
ATOM   3285  H HH21 . ARG A 1 255 ? -17.150 11.245  29.887 1.00 10.19 ?  221  ARG A HH21 1 
ATOM   3286  H HH22 . ARG A 1 255 ? -17.642 12.644  30.025 1.00 10.19 ?  221  ARG A HH22 1 
ATOM   3287  N N    . VAL A 1 256 ? -22.266 6.431   33.339 1.00 10.15 ?  222  VAL A N    1 
ATOM   3288  C CA   . VAL A 1 256 ? -23.499 6.287   34.108 1.00 9.82  ?  222  VAL A CA   1 
ATOM   3289  C C    . VAL A 1 256 ? -24.220 7.630   34.093 1.00 10.63 ?  222  VAL A C    1 
ATOM   3290  O O    . VAL A 1 256 ? -23.684 8.639   34.570 1.00 12.24 ?  222  VAL A O    1 
ATOM   3291  C CB   . VAL A 1 256 ? -23.199 5.820   35.535 1.00 11.53 ?  222  VAL A CB   1 
ATOM   3292  C CG1  . VAL A 1 256 ? -24.478 5.828   36.375 1.00 12.37 ?  222  VAL A CG1  1 
ATOM   3293  C CG2  . VAL A 1 256 ? -22.560 4.457   35.537 1.00 11.92 ?  222  VAL A CG2  1 
ATOM   3294  H H    . VAL A 1 256 ? -21.540 6.344   33.791 1.00 12.17 ?  222  VAL A H    1 
ATOM   3295  H HA   . VAL A 1 256 ? -24.072 5.623   33.695 1.00 11.79 ?  222  VAL A HA   1 
ATOM   3296  H HB   . VAL A 1 256 ? -22.567 6.436   35.938 1.00 13.84 ?  222  VAL A HB   1 
ATOM   3297  H HG11 . VAL A 1 256 ? -24.284 5.455   37.249 1.00 14.84 ?  222  VAL A HG11 1 
ATOM   3298  H HG12 . VAL A 1 256 ? -24.790 6.742   36.467 1.00 14.84 ?  222  VAL A HG12 1 
ATOM   3299  H HG13 . VAL A 1 256 ? -25.152 5.292   35.929 1.00 14.84 ?  222  VAL A HG13 1 
ATOM   3300  H HG21 . VAL A 1 256 ? -22.344 4.211   36.450 1.00 14.30 ?  222  VAL A HG21 1 
ATOM   3301  H HG22 . VAL A 1 256 ? -23.183 3.815   35.160 1.00 14.30 ?  222  VAL A HG22 1 
ATOM   3302  H HG23 . VAL A 1 256 ? -21.751 4.486   35.002 1.00 14.30 ?  222  VAL A HG23 1 
ATOM   3303  N N    . ARG A 1 257 ? -25.451 7.644   33.563 1.00 10.93 ?  223  ARG A N    1 
ATOM   3304  C CA   . ARG A 1 257 ? -26.266 8.853   33.461 1.00 11.40 ?  223  ARG A CA   1 
ATOM   3305  C C    . ARG A 1 257 ? -27.720 8.453   33.684 1.00 12.09 ?  223  ARG A C    1 
ATOM   3306  O O    . ARG A 1 257 ? -28.199 7.510   33.036 1.00 12.32 ?  223  ARG A O    1 
ATOM   3307  C CB   . ARG A 1 257 ? -26.176 9.515   32.080 1.00 11.44 ?  223  ARG A CB   1 
ATOM   3308  C CG   . ARG A 1 257 ? -24.828 10.139  31.689 1.00 10.44 ?  223  ARG A CG   1 
ATOM   3309  C CD   . ARG A 1 257 ? -24.368 11.254  32.594 1.00 9.80  ?  223  ARG A CD   1 
ATOM   3310  N NE   . ARG A 1 257 ? -25.416 12.211  32.911 1.00 11.05 ?  223  ARG A NE   1 
ATOM   3311  C CZ   . ARG A 1 257 ? -25.206 13.329  33.586 1.00 11.55 ?  223  ARG A CZ   1 
ATOM   3312  N NH1  . ARG A 1 257 ? -23.997 13.679  33.963 1.00 11.79 ?  223  ARG A NH1  1 
ATOM   3313  N NH2  . ARG A 1 257 ? -26.240 14.109  33.886 1.00 12.26 ?  223  ARG A NH2  1 
ATOM   3314  H H    . ARG A 1 257 ? -25.842 6.945   33.250 1.00 13.12 ?  223  ARG A H    1 
ATOM   3315  H HA   . ARG A 1 257 ? -25.958 9.474   34.139 1.00 13.68 ?  223  ARG A HA   1 
ATOM   3316  H HB2  . ARG A 1 257 ? -26.379 8.841   31.412 1.00 13.73 ?  223  ARG A HB2  1 
ATOM   3317  H HB3  . ARG A 1 257 ? -26.836 10.225  32.046 1.00 13.73 ?  223  ARG A HB3  1 
ATOM   3318  H HG2  . ARG A 1 257 ? -24.148 9.447   31.710 1.00 12.52 ?  223  ARG A HG2  1 
ATOM   3319  H HG3  . ARG A 1 257 ? -24.903 10.503  30.793 1.00 12.52 ?  223  ARG A HG3  1 
ATOM   3320  H HD2  . ARG A 1 257 ? -24.053 10.872  33.428 1.00 11.76 ?  223  ARG A HD2  1 
ATOM   3321  H HD3  . ARG A 1 257 ? -23.649 11.737  32.157 1.00 11.76 ?  223  ARG A HD3  1 
ATOM   3322  H HE   . ARG A 1 257 ? -26.216 12.040  32.646 1.00 13.26 ?  223  ARG A HE   1 
ATOM   3323  H HH11 . ARG A 1 257 ? -23.324 13.177  33.772 1.00 14.15 ?  223  ARG A HH11 1 
ATOM   3324  H HH12 . ARG A 1 257 ? -23.877 14.409  34.401 1.00 14.15 ?  223  ARG A HH12 1 
ATOM   3325  H HH21 . ARG A 1 257 ? -27.033 13.885  33.642 1.00 14.71 ?  223  ARG A HH21 1 
ATOM   3326  H HH22 . ARG A 1 257 ? -26.115 14.838  34.324 1.00 14.71 ?  223  ARG A HH22 1 
ATOM   3327  N N    . PRO A 1 258 ? -28.478 9.190   34.503 1.00 13.32 ?  224  PRO A N    1 
ATOM   3328  C CA   . PRO A 1 258 ? -29.910 8.868   34.590 1.00 14.47 ?  224  PRO A CA   1 
ATOM   3329  C C    . PRO A 1 258 ? -30.625 9.057   33.260 1.00 16.44 ?  224  PRO A C    1 
ATOM   3330  O O    . PRO A 1 258 ? -31.622 8.375   32.987 1.00 17.47 ?  224  PRO A O    1 
ATOM   3331  C CB   . PRO A 1 258 ? -30.439 9.806   35.686 1.00 16.83 ?  224  PRO A CB   1 
ATOM   3332  C CG   . PRO A 1 258 ? -29.381 10.733  35.997 1.00 18.62 ?  224  PRO A CG   1 
ATOM   3333  C CD   . PRO A 1 258 ? -28.063 10.217  35.466 1.00 13.52 ?  224  PRO A CD   1 
ATOM   3334  H HA   . PRO A 1 258 ? -30.035 7.958   34.901 1.00 17.37 ?  224  PRO A HA   1 
ATOM   3335  H HB2  . PRO A 1 258 ? -31.219 10.279  35.356 1.00 20.19 ?  224  PRO A HB2  1 
ATOM   3336  H HB3  . PRO A 1 258 ? -30.675 9.285   36.470 1.00 20.19 ?  224  PRO A HB3  1 
ATOM   3337  H HG2  . PRO A 1 258 ? -29.588 11.587  35.586 1.00 22.34 ?  224  PRO A HG2  1 
ATOM   3338  H HG3  . PRO A 1 258 ? -29.330 10.832  36.960 1.00 22.34 ?  224  PRO A HG3  1 
ATOM   3339  H HD2  . PRO A 1 258 ? -27.566 10.924  35.026 1.00 16.23 ?  224  PRO A HD2  1 
ATOM   3340  H HD3  . PRO A 1 258 ? -27.531 9.830   36.178 1.00 16.23 ?  224  PRO A HD3  1 
ATOM   3341  N N    . GLU A 1 259 ? -30.118 9.943   32.398 1.00 13.65 ?  225  GLU A N    1 
ATOM   3342  C CA   . GLU A 1 259 ? -30.721 10.241  31.117 1.00 12.95 ?  225  GLU A CA   1 
ATOM   3343  C C    . GLU A 1 259 ? -30.447 9.183   30.061 1.00 14.07 ?  225  GLU A C    1 
ATOM   3344  O O    . GLU A 1 259 ? -31.102 9.198   29.008 1.00 16.04 ?  225  GLU A O    1 
ATOM   3345  C CB   . GLU A 1 259 ? -30.173 11.586  30.614 1.00 14.62 ?  225  GLU A CB   1 
ATOM   3346  C CG   . GLU A 1 259 ? -30.320 12.757  31.599 1.00 14.68 ?  225  GLU A CG   1 
ATOM   3347  C CD   . GLU A 1 259 ? -29.149 12.932  32.553 1.00 14.44 ?  225  GLU A CD   1 
ATOM   3348  O OE1  . GLU A 1 259 ? -28.285 12.032  32.636 1.00 13.46 ?  225  GLU A OE1  1 
ATOM   3349  O OE2  . GLU A 1 259 ? -29.088 13.970  33.254 1.00 16.17 ?  225  GLU A OE2  1 
ATOM   3350  H H    . GLU A 1 259 ? -29.401 10.395  32.546 1.00 16.38 ?  225  GLU A H    1 
ATOM   3351  H HA   . GLU A 1 259 ? -31.682 10.301  31.230 1.00 15.54 ?  225  GLU A HA   1 
ATOM   3352  H HB2  . GLU A 1 259 ? -29.228 11.481  30.426 1.00 17.55 ?  225  GLU A HB2  1 
ATOM   3353  H HB3  . GLU A 1 259 ? -30.648 11.827  29.804 1.00 17.55 ?  225  GLU A HB3  1 
ATOM   3354  H HG2  . GLU A 1 259 ? -30.408 13.578  31.091 1.00 17.62 ?  225  GLU A HG2  1 
ATOM   3355  H HG3  . GLU A 1 259 ? -31.114 12.611  32.136 1.00 17.62 ?  225  GLU A HG3  1 
ATOM   3356  N N    . PHE A 1 260 ? -29.487 8.292   30.293 1.00 11.70 ?  226  PHE A N    1 
ATOM   3357  C CA   . PHE A 1 260 ? -29.101 7.276   29.320 1.00 12.17 ?  226  PHE A CA   1 
ATOM   3358  C C    . PHE A 1 260 ? -29.625 5.933   29.823 1.00 12.20 ?  226  PHE A C    1 
ATOM   3359  O O    . PHE A 1 260 ? -29.061 5.358   30.751 1.00 13.36 ?  226  PHE A O    1 
ATOM   3360  C CB   . PHE A 1 260 ? -27.578 7.139   29.195 1.00 12.37 ?  226  PHE A CB   1 
ATOM   3361  C CG   . PHE A 1 260 ? -26.844 8.335   28.600 1.00 12.17 ?  226  PHE A CG   1 
ATOM   3362  C CD1  . PHE A 1 260 ? -27.486 9.470   28.134 1.00 12.01 ?  226  PHE A CD1  1 
ATOM   3363  C CD2  . PHE A 1 260 ? -25.457 8.277   28.501 1.00 12.10 ?  226  PHE A CD2  1 
ATOM   3364  C CE1  . PHE A 1 260 ? -26.739 10.534  27.587 1.00 12.60 ?  226  PHE A CE1  1 
ATOM   3365  C CE2  . PHE A 1 260 ? -24.717 9.330   27.960 1.00 12.27 ?  226  PHE A CE2  1 
ATOM   3366  C CZ   . PHE A 1 260 ? -25.362 10.446  27.501 1.00 12.29 ?  226  PHE A CZ   1 
ATOM   3367  H H    . PHE A 1 260 ? -29.035 8.256   31.024 1.00 14.04 ?  226  PHE A H    1 
ATOM   3368  H HA   . PHE A 1 260 ? -29.486 7.527   28.465 1.00 14.60 ?  226  PHE A HA   1 
ATOM   3369  H HB2  . PHE A 1 260 ? -27.214 6.991   30.082 1.00 14.85 ?  226  PHE A HB2  1 
ATOM   3370  H HB3  . PHE A 1 260 ? -27.389 6.375   28.627 1.00 14.85 ?  226  PHE A HB3  1 
ATOM   3371  H HD1  . PHE A 1 260 ? -28.413 9.530   28.181 1.00 14.41 ?  226  PHE A HD1  1 
ATOM   3372  H HD2  . PHE A 1 260 ? -25.012 7.518   28.802 1.00 14.52 ?  226  PHE A HD2  1 
ATOM   3373  H HE1  . PHE A 1 260 ? -27.174 11.297  27.283 1.00 15.12 ?  226  PHE A HE1  1 
ATOM   3374  H HE2  . PHE A 1 260 ? -23.790 9.273   27.912 1.00 14.72 ?  226  PHE A HE2  1 
ATOM   3375  H HZ   . PHE A 1 260 ? -24.873 11.147  27.132 1.00 14.75 ?  226  PHE A HZ   1 
ATOM   3376  N N    . GLU A 1 261 ? -30.664 5.403   29.187 1.00 14.80 ?  227  GLU A N    1 
ATOM   3377  C CA   . GLU A 1 261 ? -31.194 4.122   29.641 1.00 15.72 ?  227  GLU A CA   1 
ATOM   3378  C C    . GLU A 1 261 ? -30.136 3.025   29.657 1.00 15.83 ?  227  GLU A C    1 
ATOM   3379  O O    . GLU A 1 261 ? -30.177 2.135   30.517 1.00 16.04 ?  227  GLU A O    1 
ATOM   3380  C CB   . GLU A 1 261 ? -32.365 3.695   28.756 1.00 20.98 ?  227  GLU A CB   1 
ATOM   3381  C CG   . GLU A 1 261 ? -33.482 2.993   29.517 1.00 38.46 ?  227  GLU A CG   1 
ATOM   3382  H H    . GLU A 1 261 ? -31.067 5.751   28.511 1.00 17.76 ?  227  GLU A H    1 
ATOM   3383  H HA   . GLU A 1 261 ? -31.515 4.237   30.549 1.00 18.87 ?  227  GLU A HA   1 
ATOM   3384  H HB2  . GLU A 1 261 ? -32.742 4.484   28.336 1.00 25.18 ?  227  GLU A HB2  1 
ATOM   3385  H HB3  . GLU A 1 261 ? -32.037 3.083   28.079 1.00 25.18 ?  227  GLU A HB3  1 
ATOM   3386  H HG2  . GLU A 1 261 ? -34.202 2.786   28.901 1.00 46.15 ?  227  GLU A HG2  1 
ATOM   3387  H HG3  . GLU A 1 261 ? -33.134 2.177   29.907 1.00 46.15 ?  227  GLU A HG3  1 
ATOM   3388  N N    . GLU A 1 262 ? -29.181 3.055   28.724 1.00 13.30 ?  228  GLU A N    1 
ATOM   3389  C CA   . GLU A 1 262 ? -28.140 2.039   28.668 1.00 14.56 ?  228  GLU A CA   1 
ATOM   3390  C C    . GLU A 1 262 ? -26.753 2.604   28.966 1.00 13.06 ?  228  GLU A C    1 
ATOM   3391  O O    . GLU A 1 262 ? -25.740 1.966   28.649 1.00 12.82 ?  228  GLU A O    1 
ATOM   3392  C CB   . GLU A 1 262 ? -28.166 1.311   27.324 1.00 15.06 ?  228  GLU A CB   1 
ATOM   3393  C CG   . GLU A 1 262 ? -29.527 0.696   26.975 1.00 18.64 ?  228  GLU A CG   1 
ATOM   3394  C CD   . GLU A 1 262 ? -29.505 0.021   25.627 1.00 25.21 ?  228  GLU A CD   1 
ATOM   3395  O OE1  . GLU A 1 262 ? -28.763 -0.970  25.493 1.00 34.35 ?  228  GLU A OE1  1 
ATOM   3396  O OE2  . GLU A 1 262 ? -30.201 0.496   24.703 1.00 27.57 ?  228  GLU A OE2  1 
ATOM   3397  H H    . GLU A 1 262 ? -29.120 3.656   28.112 1.00 15.96 ?  228  GLU A H    1 
ATOM   3398  H HA   . GLU A 1 262 ? -28.325 1.376   29.352 1.00 17.47 ?  228  GLU A HA   1 
ATOM   3399  H HB2  . GLU A 1 262 ? -27.939 1.943   26.623 1.00 18.08 ?  228  GLU A HB2  1 
ATOM   3400  H HB3  . GLU A 1 262 ? -27.514 0.593   27.346 1.00 18.08 ?  228  GLU A HB3  1 
ATOM   3401  H HG2  . GLU A 1 262 ? -29.759 0.032   27.644 1.00 22.37 ?  228  GLU A HG2  1 
ATOM   3402  H HG3  . GLU A 1 262 ? -30.199 1.395   26.955 1.00 22.37 ?  228  GLU A HG3  1 
ATOM   3403  N N    . ASN A 1 263 ? -26.695 3.766   29.618 1.00 11.51 ?  229  ASN A N    1 
ATOM   3404  C CA   . ASN A 1 263 ? -25.439 4.336   30.105 1.00 12.01 ?  229  ASN A CA   1 
ATOM   3405  C C    . ASN A 1 263 ? -24.412 4.508   28.994 1.00 11.23 ?  229  ASN A C    1 
ATOM   3406  O O    . ASN A 1 263 ? -23.203 4.372   29.218 1.00 10.67 ?  229  ASN A O    1 
ATOM   3407  C CB   . ASN A 1 263 ? -24.903 3.545   31.292 1.00 11.86 ?  229  ASN A CB   1 
ATOM   3408  C CG   . ASN A 1 263 ? -25.722 3.786   32.536 1.00 11.27 ?  229  ASN A CG   1 
ATOM   3409  O OD1  . ASN A 1 263 ? -26.331 4.851   32.700 1.00 11.61 ?  229  ASN A OD1  1 
ATOM   3410  N ND2  . ASN A 1 263 ? -25.764 2.793   33.410 1.00 11.94 ?  229  ASN A ND2  1 
ATOM   3411  H H    . ASN A 1 263 ? -27.383 4.251   29.795 1.00 13.81 ?  229  ASN A H    1 
ATOM   3412  H HA   . ASN A 1 263 ? -25.614 5.235   30.423 1.00 14.41 ?  229  ASN A HA   1 
ATOM   3413  H HB2  . ASN A 1 263 ? -24.933 2.598   31.086 1.00 14.23 ?  229  ASN A HB2  1 
ATOM   3414  H HB3  . ASN A 1 263 ? -23.989 3.816   31.472 1.00 14.23 ?  229  ASN A HB3  1 
ATOM   3415  H HD21 . ASN A 1 263 ? -26.217 2.878   34.136 1.00 14.33 ?  229  ASN A HD21 1 
ATOM   3416  H HD22 . ASN A 1 263 ? -25.338 2.063   33.253 1.00 14.33 ?  229  ASN A HD22 1 
ATOM   3417  N N    . GLY A 1 264 ? -24.895 4.854   27.797 1.00 10.87 ?  230  GLY A N    1 
ATOM   3418  C CA   . GLY A 1 264 ? -24.043 5.162   26.665 1.00 13.17 ?  230  GLY A CA   1 
ATOM   3419  C C    . GLY A 1 264 ? -23.960 4.074   25.617 1.00 12.17 ?  230  GLY A C    1 
ATOM   3420  O O    . GLY A 1 264 ? -23.591 4.368   24.477 1.00 11.34 ?  230  GLY A O    1 
ATOM   3421  H H    . GLY A 1 264 ? -25.734 4.918   27.621 1.00 13.05 ?  230  GLY A H    1 
ATOM   3422  H HA2  . GLY A 1 264 ? -24.378 5.963   26.233 1.00 15.81 ?  230  GLY A HA2  1 
ATOM   3423  H HA3  . GLY A 1 264 ? -23.144 5.329   26.989 1.00 15.81 ?  230  GLY A HA3  1 
ATOM   3424  N N    . LEU A 1 265 ? -24.301 2.830   25.968 1.00 11.96 ?  231  LEU A N    1 
ATOM   3425  C CA   . LEU A 1 265 ? -24.241 1.733   24.999 1.00 12.06 ?  231  LEU A CA   1 
ATOM   3426  C C    . LEU A 1 265 ? -25.142 1.994   23.805 1.00 14.23 ?  231  LEU A C    1 
ATOM   3427  O O    . LEU A 1 265 ? -24.871 1.504   22.701 1.00 15.10 ?  231  LEU A O    1 
ATOM   3428  C CB   . LEU A 1 265 ? -24.691 0.431   25.664 1.00 14.42 ?  231  LEU A CB   1 
ATOM   3429  C CG   . LEU A 1 265 ? -23.803 -0.131  26.759 1.00 18.89 ?  231  LEU A CG   1 
ATOM   3430  C CD1  . LEU A 1 265 ? -24.357 -1.453  27.249 1.00 22.53 ?  231  LEU A CD1  1 
ATOM   3431  C CD2  . LEU A 1 265 ? -22.400 -0.326  26.247 1.00 21.63 ?  231  LEU A CD2  1 
ATOM   3432  H H    . LEU A 1 265 ? -24.568 2.597   26.752 1.00 14.35 ?  231  LEU A H    1 
ATOM   3433  H HA   . LEU A 1 265 ? -23.323 1.646   24.696 1.00 14.47 ?  231  LEU A HA   1 
ATOM   3434  H HB2  . LEU A 1 265 ? -25.563 0.584   26.059 1.00 17.30 ?  231  LEU A HB2  1 
ATOM   3435  H HB3  . LEU A 1 265 ? -24.754 -0.249  24.974 1.00 17.30 ?  231  LEU A HB3  1 
ATOM   3436  H HG   . LEU A 1 265 ? -23.777 0.494   27.500 1.00 22.67 ?  231  LEU A HG   1 
ATOM   3437  H HD11 . LEU A 1 265 ? -23.745 -1.831  27.899 1.00 27.03 ?  231  LEU A HD11 1 
ATOM   3438  H HD12 . LEU A 1 265 ? -25.223 -1.299  27.659 1.00 27.03 ?  231  LEU A HD12 1 
ATOM   3439  H HD13 . LEU A 1 265 ? -24.451 -2.055  26.494 1.00 27.03 ?  231  LEU A HD13 1 
ATOM   3440  H HD21 . LEU A 1 265 ? -21.873 -0.768  26.931 1.00 25.96 ?  231  LEU A HD21 1 
ATOM   3441  H HD22 . LEU A 1 265 ? -22.429 -0.872  25.446 1.00 25.96 ?  231  LEU A HD22 1 
ATOM   3442  H HD23 . LEU A 1 265 ? -22.016 0.541   26.043 1.00 25.96 ?  231  LEU A HD23 1 
ATOM   3443  N N    . GLU A 1 266 ? -26.227 2.739   24.007 1.00 11.08 ?  232  GLU A N    1 
ATOM   3444  C CA   . GLU A 1 266 ? -27.169 3.005   22.932 1.00 12.50 ?  232  GLU A CA   1 
ATOM   3445  C C    . GLU A 1 266 ? -26.608 3.965   21.902 1.00 12.52 ?  232  GLU A C    1 
ATOM   3446  O O    . GLU A 1 266 ? -27.200 4.120   20.830 1.00 13.61 ?  232  GLU A O    1 
ATOM   3447  C CB   . GLU A 1 266 ? -28.498 3.535   23.487 1.00 14.28 ?  232  GLU A CB   1 
ATOM   3448  C CG   . GLU A 1 266 ? -28.412 4.871   24.242 1.00 13.74 ?  232  GLU A CG   1 
ATOM   3449  C CD   . GLU A 1 266 ? -28.195 4.700   25.739 1.00 14.09 ?  232  GLU A CD   1 
ATOM   3450  O OE1  . GLU A 1 266 ? -27.105 4.273   26.146 1.00 13.03 ?  232  GLU A OE1  1 
ATOM   3451  O OE2  . GLU A 1 266 ? -29.122 4.995   26.534 1.00 17.30 ?  232  GLU A OE2  1 
ATOM   3452  H H    . GLU A 1 266 ? -26.437 3.100   24.759 1.00 13.30 ?  232  GLU A H    1 
ATOM   3453  H HA   . GLU A 1 266 ? -27.370 2.169   22.484 1.00 15.00 ?  232  GLU A HA   1 
ATOM   3454  H HB2  . GLU A 1 266 ? -29.110 3.661   22.745 1.00 17.13 ?  232  GLU A HB2  1 
ATOM   3455  H HB3  . GLU A 1 266 ? -28.856 2.877   24.104 1.00 17.13 ?  232  GLU A HB3  1 
ATOM   3456  H HG2  . GLU A 1 266 ? -27.669 5.384   23.889 1.00 16.49 ?  232  GLU A HG2  1 
ATOM   3457  H HG3  . GLU A 1 266 ? -29.242 5.357   24.115 1.00 16.49 ?  232  GLU A HG3  1 
ATOM   3458  N N    . TYR A 1 267 ? -25.469 4.601   22.194 1.00 11.55 ?  233  TYR A N    1 
ATOM   3459  C CA   . TYR A 1 267 ? -24.888 5.603   21.317 1.00 13.81 ?  233  TYR A CA   1 
ATOM   3460  C C    . TYR A 1 267 ? -23.596 5.126   20.688 1.00 14.08 ?  233  TYR A C    1 
ATOM   3461  O O    . TYR A 1 267 ? -22.925 5.909   20.012 1.00 18.89 ?  233  TYR A O    1 
ATOM   3462  C CB   . TYR A 1 267 ? -24.614 6.878   22.113 1.00 15.62 ?  233  TYR A CB   1 
ATOM   3463  C CG   . TYR A 1 267 ? -25.832 7.527   22.705 1.00 13.55 ?  233  TYR A CG   1 
ATOM   3464  C CD1  . TYR A 1 267 ? -26.850 7.976   21.896 1.00 12.95 ?  233  TYR A CD1  1 
ATOM   3465  C CD2  . TYR A 1 267 ? -25.955 7.715   24.074 1.00 15.18 ?  233  TYR A CD2  1 
ATOM   3466  C CE1  . TYR A 1 267 ? -27.965 8.592   22.424 1.00 15.75 ?  233  TYR A CE1  1 
ATOM   3467  C CE2  . TYR A 1 267 ? -27.053 8.321   24.613 1.00 17.38 ?  233  TYR A CE2  1 
ATOM   3468  C CZ   . TYR A 1 267 ? -28.068 8.759   23.793 1.00 16.83 ?  233  TYR A CZ   1 
ATOM   3469  O OH   . TYR A 1 267 ? -29.193 9.382   24.320 1.00 21.19 ?  233  TYR A OH   1 
ATOM   3470  H H    . TYR A 1 267 ? -25.012 4.462   22.909 1.00 13.86 ?  233  TYR A H    1 
ATOM   3471  H HA   . TYR A 1 267 ? -25.518 5.803   20.608 1.00 16.57 ?  233  TYR A HA   1 
ATOM   3472  H HB2  . TYR A 1 267 ? -24.015 6.661   22.844 1.00 18.75 ?  233  TYR A HB2  1 
ATOM   3473  H HB3  . TYR A 1 267 ? -24.197 7.525   21.523 1.00 18.75 ?  233  TYR A HB3  1 
ATOM   3474  H HD1  . TYR A 1 267 ? -26.785 7.861   20.975 1.00 15.54 ?  233  TYR A HD1  1 
ATOM   3475  H HD2  . TYR A 1 267 ? -25.275 7.422   24.637 1.00 18.22 ?  233  TYR A HD2  1 
ATOM   3476  H HE1  . TYR A 1 267 ? -28.643 8.892   21.864 1.00 18.89 ?  233  TYR A HE1  1 
ATOM   3477  H HE2  . TYR A 1 267 ? -27.116 8.438   25.534 1.00 20.86 ?  233  TYR A HE2  1 
ATOM   3478  H HH   . TYR A 1 267 ? -29.696 9.640   23.699 1.00 25.43 ?  233  TYR A HH   1 
ATOM   3479  N N    . LEU A 1 268 ? -23.227 3.879   20.892 1.00 12.05 ?  234  LEU A N    1 
ATOM   3480  C CA   . LEU A 1 268 ? -21.950 3.382   20.408 1.00 14.53 ?  234  LEU A CA   1 
ATOM   3481  C C    . LEU A 1 268 ? -21.960 3.034   18.932 1.00 18.35 ?  234  LEU A C    1 
ATOM   3482  O O    . LEU A 1 268 ? -20.898 2.692   18.398 1.00 15.41 ?  234  LEU A O    1 
ATOM   3483  C CB   . LEU A 1 268 ? -21.554 2.128   21.165 1.00 18.54 ?  234  LEU A CB   1 
ATOM   3484  C CG   . LEU A 1 268 ? -20.719 2.306   22.413 1.00 24.11 ?  234  LEU A CG   1 
ATOM   3485  C CD1  . LEU A 1 268 ? -20.483 0.931   23.049 1.00 24.10 ?  234  LEU A CD1  1 
ATOM   3486  C CD2  . LEU A 1 268 ? -19.386 2.985   22.085 1.00 23.71 ?  234  LEU A CD2  1 
ATOM   3487  H H    . LEU A 1 268 ? -23.699 3.294   21.310 1.00 14.46 ?  234  LEU A H    1 
ATOM   3488  H HA   . LEU A 1 268 ? -21.292 4.077   20.565 1.00 17.43 ?  234  LEU A HA   1 
ATOM   3489  H HB2  . LEU A 1 268 ? -22.368 1.674   21.434 1.00 22.25 ?  234  LEU A HB2  1 
ATOM   3490  H HB3  . LEU A 1 268 ? -21.044 1.566   20.563 1.00 22.25 ?  234  LEU A HB3  1 
ATOM   3491  H HG   . LEU A 1 268 ? -21.184 2.877   23.044 1.00 28.93 ?  234  LEU A HG   1 
ATOM   3492  H HD11 . LEU A 1 268 ? -19.860 1.027   23.786 1.00 28.92 ?  234  LEU A HD11 1 
ATOM   3493  H HD12 . LEU A 1 268 ? -21.329 0.584   23.373 1.00 28.92 ?  234  LEU A HD12 1 
ATOM   3494  H HD13 . LEU A 1 268 ? -20.115 0.333   22.380 1.00 28.92 ?  234  LEU A HD13 1 
ATOM   3495  H HD21 . LEU A 1 268 ? -18.776 2.858   22.829 1.00 28.46 ?  234  LEU A HD21 1 
ATOM   3496  H HD22 . LEU A 1 268 ? -19.016 2.584   21.283 1.00 28.46 ?  234  LEU A HD22 1 
ATOM   3497  H HD23 . LEU A 1 268 ? -19.540 3.931   21.942 1.00 28.46 ?  234  LEU A HD23 1 
ATOM   3498  N N    . GLY A 1 269 ? -23.113 3.110   18.264 1.00 22.44 ?  235  GLY A N    1 
ATOM   3499  C CA   . GLY A 1 269 ? -23.207 2.622   16.896 1.00 21.62 ?  235  GLY A CA   1 
ATOM   3500  C C    . GLY A 1 269 ? -22.322 3.361   15.926 1.00 15.31 ?  235  GLY A C    1 
ATOM   3501  O O    . GLY A 1 269 ? -21.969 2.817   14.867 1.00 14.87 ?  235  GLY A O    1 
ATOM   3502  H H    . GLY A 1 269 ? -23.843 3.437   18.579 1.00 26.93 ?  235  GLY A H    1 
ATOM   3503  H HA2  . GLY A 1 269 ? -22.957 1.685   16.878 1.00 25.94 ?  235  GLY A HA2  1 
ATOM   3504  H HA3  . GLY A 1 269 ? -24.125 2.710   16.593 1.00 25.94 ?  235  GLY A HA3  1 
ATOM   3505  N N    . TYR A 1 270 ? -21.949 4.591   16.254 1.00 13.25 ?  236  TYR A N    1 
ATOM   3506  C CA   . TYR A 1 270 ? -21.138 5.369   15.351 1.00 12.00 ?  236  TYR A CA   1 
ATOM   3507  C C    . TYR A 1 270 ? -19.657 5.084   15.496 1.00 10.01 ?  236  TYR A C    1 
ATOM   3508  O O    . TYR A 1 270 ? -18.881 5.530   14.649 1.00 13.39 ?  236  TYR A O    1 
ATOM   3509  C CB   . TYR A 1 270 ? -21.282 6.872   15.606 1.00 15.81 ?  236  TYR A CB   1 
ATOM   3510  C CG   . TYR A 1 270 ? -22.654 7.428   15.349 1.00 16.61 ?  236  TYR A CG   1 
ATOM   3511  C CD1  . TYR A 1 270 ? -23.140 7.569   14.063 1.00 14.58 ?  236  TYR A CD1  1 
ATOM   3512  C CD2  . TYR A 1 270 ? -23.452 7.809   16.398 1.00 21.25 ?  236  TYR A CD2  1 
ATOM   3513  C CE1  . TYR A 1 270 ? -24.406 8.081   13.836 1.00 16.01 ?  236  TYR A CE1  1 
ATOM   3514  C CE2  . TYR A 1 270 ? -24.702 8.332   16.181 1.00 22.63 ?  236  TYR A CE2  1 
ATOM   3515  C CZ   . TYR A 1 270 ? -25.167 8.456   14.900 1.00 19.48 ?  236  TYR A CZ   1 
ATOM   3516  O OH   . TYR A 1 270 ? -26.429 8.969   14.690 1.00 22.11 ?  236  TYR A OH   1 
ATOM   3517  H H    . TYR A 1 270 ? -22.154 4.987   16.990 1.00 15.90 ?  236  TYR A H    1 
ATOM   3518  H HA   . TYR A 1 270 ? -21.454 5.156   14.459 1.00 14.40 ?  236  TYR A HA   1 
ATOM   3519  H HB2  . TYR A 1 270 ? -21.065 7.049   16.535 1.00 18.97 ?  236  TYR A HB2  1 
ATOM   3520  H HB3  . TYR A 1 270 ? -20.663 7.343   15.025 1.00 18.97 ?  236  TYR A HB3  1 
ATOM   3521  H HD1  . TYR A 1 270 ? -22.610 7.317   13.341 1.00 17.50 ?  236  TYR A HD1  1 
ATOM   3522  H HD2  . TYR A 1 270 ? -23.141 7.712   17.269 1.00 25.50 ?  236  TYR A HD2  1 
ATOM   3523  H HE1  . TYR A 1 270 ? -24.732 8.167   12.970 1.00 19.21 ?  236  TYR A HE1  1 
ATOM   3524  H HE2  . TYR A 1 270 ? -25.230 8.599   16.898 1.00 27.16 ?  236  TYR A HE2  1 
ATOM   3525  H HH   . TYR A 1 270 ? -26.379 9.683   14.250 1.00 26.54 ?  236  TYR A HH   1 
ATOM   3526  N N    . PHE A 1 271 ? -19.249 4.369   16.541 1.00 8.63  ?  237  PHE A N    1 
ATOM   3527  C CA   . PHE A 1 271 ? -17.862 4.386   17.006 1.00 7.31  ?  237  PHE A CA   1 
ATOM   3528  C C    . PHE A 1 271 ? -17.250 2.996   17.087 1.00 8.17  ?  237  PHE A C    1 
ATOM   3529  O O    . PHE A 1 271 ? -17.945 2.010   17.300 1.00 9.34  ?  237  PHE A O    1 
ATOM   3530  C CB   . PHE A 1 271 ? -17.801 5.061   18.373 1.00 8.37  ?  237  PHE A CB   1 
ATOM   3531  C CG   . PHE A 1 271 ? -18.485 6.409   18.410 1.00 8.28  ?  237  PHE A CG   1 
ATOM   3532  C CD1  . PHE A 1 271 ? -18.039 7.428   17.602 1.00 10.13 ?  237  PHE A CD1  1 
ATOM   3533  C CD2  . PHE A 1 271 ? -19.590 6.646   19.207 1.00 9.19  ?  237  PHE A CD2  1 
ATOM   3534  C CE1  . PHE A 1 271 ? -18.654 8.673   17.629 1.00 10.94 ?  237  PHE A CE1  1 
ATOM   3535  C CE2  . PHE A 1 271 ? -20.209 7.904   19.216 1.00 9.80  ?  237  PHE A CE2  1 
ATOM   3536  C CZ   . PHE A 1 271 ? -19.737 8.879   18.431 1.00 10.13 ?  237  PHE A CZ   1 
ATOM   3537  H H    . PHE A 1 271 ? -19.763 3.859   17.005 1.00 10.35 ?  237  PHE A H    1 
ATOM   3538  H HA   . PHE A 1 271 ? -17.319 4.868   16.363 1.00 8.77  ?  237  PHE A HA   1 
ATOM   3539  H HB2  . PHE A 1 271 ? -18.236 4.489   19.024 1.00 10.05 ?  237  PHE A HB2  1 
ATOM   3540  H HB3  . PHE A 1 271 ? -16.871 5.193   18.616 1.00 10.05 ?  237  PHE A HB3  1 
ATOM   3541  H HD1  . PHE A 1 271 ? -17.319 7.283   17.032 1.00 12.16 ?  237  PHE A HD1  1 
ATOM   3542  H HD2  . PHE A 1 271 ? -19.926 5.964   19.742 1.00 11.03 ?  237  PHE A HD2  1 
ATOM   3543  H HE1  . PHE A 1 271 ? -18.328 9.365   17.100 1.00 13.13 ?  237  PHE A HE1  1 
ATOM   3544  H HE2  . PHE A 1 271 ? -20.944 8.060   19.765 1.00 11.76 ?  237  PHE A HE2  1 
ATOM   3545  H HZ   . PHE A 1 271 ? -20.154 9.711   18.433 1.00 12.15 ?  237  PHE A HZ   1 
ATOM   3546  N N    . ASN A 1 272 ? -15.924 2.931   16.958 1.00 8.72  ?  238  ASN A N    1 
ATOM   3547  C CA   . ASN A 1 272 ? -15.210 1.685   17.185 1.00 7.75  ?  238  ASN A CA   1 
ATOM   3548  C C    . ASN A 1 272 ? -15.035 1.386   18.658 1.00 8.61  ?  238  ASN A C    1 
ATOM   3549  O O    . ASN A 1 272 ? -14.654 0.270   19.001 1.00 9.34  ?  238  ASN A O    1 
ATOM   3550  C CB   . ASN A 1 272 ? -13.842 1.736   16.502 1.00 8.16  ?  238  ASN A CB   1 
ATOM   3551  C CG   . ASN A 1 272 ? -13.952 1.924   15.009 1.00 9.95  ?  238  ASN A CG   1 
ATOM   3552  O OD1  . ASN A 1 272 ? -13.641 2.976   14.455 1.00 9.91  ?  238  ASN A OD1  1 
ATOM   3553  N ND2  . ASN A 1 272 ? -14.426 0.893   14.334 1.00 9.65  ?  238  ASN A ND2  1 
ATOM   3554  H H    . ASN A 1 272 ? -15.421 3.594   16.741 1.00 10.46 ?  238  ASN A H    1 
ATOM   3555  H HA   . ASN A 1 272 ? -15.709 0.954   16.787 1.00 9.31  ?  238  ASN A HA   1 
ATOM   3556  H HB2  . ASN A 1 272 ? -13.334 2.480   16.862 1.00 9.79  ?  238  ASN A HB2  1 
ATOM   3557  H HB3  . ASN A 1 272 ? -13.373 0.903   16.667 1.00 9.79  ?  238  ASN A HB3  1 
ATOM   3558  H HD21 . ASN A 1 272 ? -14.512 0.941   13.480 1.00 11.59 ?  238  ASN A HD21 1 
ATOM   3559  H HD22 . ASN A 1 272 ? -14.649 0.173   14.749 1.00 11.59 ?  238  ASN A HD22 1 
ATOM   3560  N N    . GLY A 1 273 ? -15.248 2.357   19.542 1.00 8.11  ?  239  GLY A N    1 
ATOM   3561  C CA   . GLY A 1 273 ? -15.150 2.084   20.960 1.00 9.51  ?  239  GLY A CA   1 
ATOM   3562  C C    . GLY A 1 273 ? -15.399 3.336   21.765 1.00 6.96  ?  239  GLY A C    1 
ATOM   3563  O O    . GLY A 1 273 ? -15.677 4.415   21.224 1.00 7.61  ?  239  GLY A O    1 
ATOM   3564  H H    . GLY A 1 273 ? -15.447 3.169   19.344 1.00 9.73  ?  239  GLY A H    1 
ATOM   3565  H HA2  . GLY A 1 273 ? -15.807 1.416   21.211 1.00 11.41 ?  239  GLY A HA2  1 
ATOM   3566  H HA3  . GLY A 1 273 ? -14.264 1.750   21.169 1.00 11.41 ?  239  GLY A HA3  1 
ATOM   3567  N N    . SER A 1 274 ? -15.260 3.175   23.082 1.00 7.32  ?  240  SER A N    1 
ATOM   3568  C CA   . SER A 1 274 ? -15.417 4.283   24.006 1.00 7.52  ?  240  SER A CA   1 
ATOM   3569  C C    . SER A 1 274 ? -14.211 4.436   24.910 1.00 7.69  ?  240  SER A C    1 
ATOM   3570  O O    . SER A 1 274 ? -13.651 3.456   25.400 1.00 8.38  ?  240  SER A O    1 
ATOM   3571  C CB   . SER A 1 274 ? -16.661 4.093   24.911 1.00 7.77  ?  240  SER A CB   1 
ATOM   3572  O OG   . SER A 1 274 ? -16.936 5.247   25.701 1.00 8.35  ?  240  SER A OG   1 
ATOM   3573  H H    . SER A 1 274 ? -15.073 2.426   23.460 1.00 8.79  ?  240  SER A H    1 
ATOM   3574  H HA   . SER A 1 274 ? -15.504 5.090   23.475 1.00 9.02  ?  240  SER A HA   1 
ATOM   3575  H HB2  . SER A 1 274 ? -17.429 3.912   24.347 1.00 9.33  ?  240  SER A HB2  1 
ATOM   3576  H HB3  . SER A 1 274 ? -16.501 3.342   25.504 1.00 9.33  ?  240  SER A HB3  1 
ATOM   3577  H HG   . SER A 1 274 ? -16.299 5.393   26.228 1.00 10.02 ?  240  SER A HG   1 
ATOM   3578  N N    . TYR A 1 275 ? -13.873 5.694   25.178 1.00 6.79  ?  241  TYR A N    1 
ATOM   3579  C CA   . TYR A 1 275 ? -13.087 6.107   26.331 1.00 7.91  ?  241  TYR A CA   1 
ATOM   3580  C C    . TYR A 1 275 ? -14.013 6.285   27.532 1.00 7.03  ?  241  TYR A C    1 
ATOM   3581  O O    . TYR A 1 275 ? -15.201 6.593   27.386 1.00 8.07  ?  241  TYR A O    1 
ATOM   3582  C CB   . TYR A 1 275 ? -12.407 7.417   25.940 1.00 7.28  ?  241  TYR A CB   1 
ATOM   3583  C CG   . TYR A 1 275 ? -11.955 8.371   27.028 1.00 7.12  ?  241  TYR A CG   1 
ATOM   3584  C CD1  . TYR A 1 275 ? -12.874 9.192   27.675 1.00 6.05  ?  241  TYR A CD1  1 
ATOM   3585  C CD2  . TYR A 1 275 ? -10.599 8.551   27.320 1.00 6.90  ?  241  TYR A CD2  1 
ATOM   3586  C CE1  . TYR A 1 275 ? -12.478 10.111  28.631 1.00 7.30  ?  241  TYR A CE1  1 
ATOM   3587  C CE2  . TYR A 1 275 ? -10.194 9.483   28.257 1.00 7.05  ?  241  TYR A CE2  1 
ATOM   3588  C CZ   . TYR A 1 275 ? -11.137 10.259  28.912 1.00 7.11  ?  241  TYR A CZ   1 
ATOM   3589  O OH   . TYR A 1 275 ? -10.696 11.171  29.863 1.00 8.21  ?  241  TYR A OH   1 
ATOM   3590  H H    . TYR A 1 275 ? -14.100 6.359   24.681 1.00 8.15  ?  241  TYR A H    1 
ATOM   3591  H HA   . TYR A 1 275 ? -12.414 5.460   26.596 1.00 9.49  ?  241  TYR A HA   1 
ATOM   3592  H HB2  . TYR A 1 275 ? -11.614 7.191   25.429 1.00 8.74  ?  241  TYR A HB2  1 
ATOM   3593  H HB3  . TYR A 1 275 ? -13.029 7.912   25.385 1.00 8.74  ?  241  TYR A HB3  1 
ATOM   3594  H HD1  . TYR A 1 275 ? -13.776 9.121   27.459 1.00 7.26  ?  241  TYR A HD1  1 
ATOM   3595  H HD2  . TYR A 1 275 ? -9.962  8.036   26.879 1.00 8.28  ?  241  TYR A HD2  1 
ATOM   3596  H HE1  . TYR A 1 275 ? -13.111 10.624  29.080 1.00 8.76  ?  241  TYR A HE1  1 
ATOM   3597  H HE2  . TYR A 1 275 ? -9.290  9.590   28.447 1.00 8.46  ?  241  TYR A HE2  1 
ATOM   3598  H HH   . TYR A 1 275 ? -11.347 11.457  30.311 1.00 9.85  ?  241  TYR A HH   1 
ATOM   3599  N N    . LEU A 1 276 ? -13.474 6.026   28.721 1.00 7.09  ?  242  LEU A N    1 
ATOM   3600  C CA   . LEU A 1 276 ? -14.242 6.156   29.953 1.00 7.98  ?  242  LEU A CA   1 
ATOM   3601  C C    . LEU A 1 276 ? -13.539 7.116   30.893 1.00 8.15  ?  242  LEU A C    1 
ATOM   3602  O O    . LEU A 1 276 ? -12.339 6.976   31.143 1.00 7.88  ?  242  LEU A O    1 
ATOM   3603  C CB   . LEU A 1 276 ? -14.353 4.817   30.693 1.00 9.18  ?  242  LEU A CB   1 
ATOM   3604  C CG   . LEU A 1 276 ? -14.771 3.593   29.899 1.00 10.40 ?  242  LEU A CG   1 
ATOM   3605  C CD1  . LEU A 1 276 ? -14.640 2.325   30.718 1.00 11.75 ?  242  LEU A CD1  1 
ATOM   3606  C CD2  . LEU A 1 276 ? -16.178 3.764   29.449 1.00 13.97 ?  242  LEU A CD2  1 
ATOM   3607  H H    . LEU A 1 276 ? -12.661 5.772   28.838 1.00 8.51  ?  242  LEU A H    1 
ATOM   3608  H HA   . LEU A 1 276 ? -15.122 6.489   29.718 1.00 9.57  ?  242  LEU A HA   1 
ATOM   3609  H HB2  . LEU A 1 276 ? -13.483 4.618   31.073 1.00 11.01 ?  242  LEU A HB2  1 
ATOM   3610  H HB3  . LEU A 1 276 ? -15.007 4.925   31.401 1.00 11.01 ?  242  LEU A HB3  1 
ATOM   3611  H HG   . LEU A 1 276 ? -14.187 3.499   29.130 1.00 12.48 ?  242  LEU A HG   1 
ATOM   3612  H HD11 . LEU A 1 276 ? -15.129 1.613   30.277 1.00 14.10 ?  242  LEU A HD11 1 
ATOM   3613  H HD12 . LEU A 1 276 ? -13.701 2.089   30.785 1.00 14.10 ?  242  LEU A HD12 1 
ATOM   3614  H HD13 . LEU A 1 276 ? -15.006 2.481   31.602 1.00 14.10 ?  242  LEU A HD13 1 
ATOM   3615  H HD21 . LEU A 1 276 ? -16.419 3.019   28.877 1.00 16.76 ?  242  LEU A HD21 1 
ATOM   3616  H HD22 . LEU A 1 276 ? -16.757 3.785   30.227 1.00 16.76 ?  242  LEU A HD22 1 
ATOM   3617  H HD23 . LEU A 1 276 ? -16.253 4.596   28.958 1.00 16.76 ?  242  LEU A HD23 1 
ATOM   3618  N N    . GLU A 1 277 ? -14.305 8.074   31.417 1.00 7.51  ?  243  GLU A N    1 
ATOM   3619  C CA   . GLU A 1 277 ? -13.874 8.924   32.517 1.00 8.45  ?  243  GLU A CA   1 
ATOM   3620  C C    . GLU A 1 277 ? -15.047 9.101   33.471 1.00 8.77  ?  243  GLU A C    1 
ATOM   3621  O O    . GLU A 1 277 ? -16.179 8.686   33.206 1.00 9.54  ?  243  GLU A O    1 
ATOM   3622  C CB   . GLU A 1 277 ? -13.329 10.276  32.025 1.00 8.31  ?  243  GLU A CB   1 
ATOM   3623  C CG   . GLU A 1 277 ? -14.398 11.168  31.434 1.00 7.46  ?  243  GLU A CG   1 
ATOM   3624  C CD   . GLU A 1 277 ? -13.881 12.487  30.906 1.00 7.79  ?  243  GLU A CD   1 
ATOM   3625  O OE1  . GLU A 1 277 ? -12.639 12.690  30.866 1.00 8.85  ?  243  GLU A OE1  1 
ATOM   3626  O OE2  . GLU A 1 277 ? -14.726 13.322  30.504 1.00 9.26  ?  243  GLU A OE2  1 
ATOM   3627  H H    . GLU A 1 277 ? -15.100 8.253   31.141 1.00 9.02  ?  243  GLU A H    1 
ATOM   3628  H HA   . GLU A 1 277 ? -13.153 8.492   33.001 1.00 10.14 ?  243  GLU A HA   1 
ATOM   3629  H HB2  . GLU A 1 277 ? -12.930 10.745  32.775 1.00 9.97  ?  243  GLU A HB2  1 
ATOM   3630  H HB3  . GLU A 1 277 ? -12.662 10.115  31.340 1.00 9.97  ?  243  GLU A HB3  1 
ATOM   3631  H HG2  . GLU A 1 277 ? -14.819 10.701  30.696 1.00 8.96  ?  243  GLU A HG2  1 
ATOM   3632  H HG3  . GLU A 1 277 ? -15.054 11.364  32.121 1.00 8.96  ?  243  GLU A HG3  1 
ATOM   3633  N N    . GLY A 1 278 ? -14.762 9.722   34.612 1.00 8.87  ?  244  GLY A N    1 
ATOM   3634  C CA   . GLY A 1 278 ? -15.794 9.821   35.627 1.00 10.81 ?  244  GLY A CA   1 
ATOM   3635  C C    . GLY A 1 278 ? -16.232 8.476   36.152 1.00 11.29 ?  244  GLY A C    1 
ATOM   3636  O O    . GLY A 1 278 ? -17.315 8.368   36.733 1.00 12.23 ?  244  GLY A O    1 
ATOM   3637  H H    . GLY A 1 278 ? -14.006 10.080  34.812 1.00 10.65 ?  244  GLY A H    1 
ATOM   3638  H HA2  . GLY A 1 278 ? -15.459 10.344  36.373 1.00 12.98 ?  244  GLY A HA2  1 
ATOM   3639  H HA3  . GLY A 1 278 ? -16.569 10.268  35.251 1.00 12.98 ?  244  GLY A HA3  1 
ATOM   3640  N N    . PHE A 1 279 ? -15.405 7.445   35.981 1.00 9.58  ?  245  PHE A N    1 
ATOM   3641  C CA   . PHE A 1 279 ? -15.878 6.078   36.150 1.00 10.13 ?  245  PHE A CA   1 
ATOM   3642  C C    . PHE A 1 279 ? -16.091 5.734   37.612 1.00 12.40 ?  245  PHE A C    1 
ATOM   3643  O O    . PHE A 1 279 ? -16.978 4.930   37.934 1.00 11.79 ?  245  PHE A O    1 
ATOM   3644  C CB   . PHE A 1 279 ? -14.879 5.123   35.513 1.00 10.79 ?  245  PHE A CB   1 
ATOM   3645  C CG   . PHE A 1 279 ? -15.449 3.765   35.220 1.00 10.34 ?  245  PHE A CG   1 
ATOM   3646  C CD1  . PHE A 1 279 ? -16.396 3.596   34.233 1.00 10.65 ?  245  PHE A CD1  1 
ATOM   3647  C CD2  . PHE A 1 279 ? -15.041 2.657   35.949 1.00 10.91 ?  245  PHE A CD2  1 
ATOM   3648  C CE1  . PHE A 1 279 ? -16.922 2.334   33.968 1.00 10.52 ?  245  PHE A CE1  1 
ATOM   3649  C CE2  . PHE A 1 279 ? -15.555 1.404   35.683 1.00 11.14 ?  245  PHE A CE2  1 
ATOM   3650  C CZ   . PHE A 1 279 ? -16.479 1.239   34.686 1.00 11.92 ?  245  PHE A CZ   1 
ATOM   3651  H H    . PHE A 1 279 ? -14.575 7.511   35.770 1.00 11.50 ?  245  PHE A H    1 
ATOM   3652  H HA   . PHE A 1 279 ? -16.731 5.974   35.701 1.00 12.16 ?  245  PHE A HA   1 
ATOM   3653  H HB2  . PHE A 1 279 ? -14.573 5.504   34.675 1.00 12.95 ?  245  PHE A HB2  1 
ATOM   3654  H HB3  . PHE A 1 279 ? -14.129 5.006   36.118 1.00 12.95 ?  245  PHE A HB3  1 
ATOM   3655  H HD1  . PHE A 1 279 ? -16.686 4.330   33.741 1.00 12.78 ?  245  PHE A HD1  1 
ATOM   3656  H HD2  . PHE A 1 279 ? -14.412 2.760   36.626 1.00 13.09 ?  245  PHE A HD2  1 
ATOM   3657  H HE1  . PHE A 1 279 ? -17.570 2.228   33.309 1.00 12.62 ?  245  PHE A HE1  1 
ATOM   3658  H HE2  . PHE A 1 279 ? -15.273 0.671   36.181 1.00 13.37 ?  245  PHE A HE2  1 
ATOM   3659  H HZ   . PHE A 1 279 ? -16.808 0.391   34.492 1.00 14.30 ?  245  PHE A HZ   1 
ATOM   3660  N N    . ASP A 1 280 ? -15.318 6.345   38.505 1.00 12.02 ?  246  ASP A N    1 
ATOM   3661  C CA   . ASP A 1 280 ? -15.461 6.136   39.940 1.00 13.07 ?  246  ASP A CA   1 
ATOM   3662  C C    . ASP A 1 280 ? -15.915 7.391   40.667 1.00 13.79 ?  246  ASP A C    1 
ATOM   3663  O O    . ASP A 1 280 ? -15.723 7.493   41.892 1.00 17.57 ?  246  ASP A O    1 
ATOM   3664  C CB   . ASP A 1 280 ? -14.173 5.576   40.548 1.00 13.52 ?  246  ASP A CB   1 
ATOM   3665  C CG   . ASP A 1 280 ? -12.983 6.485   40.378 1.00 15.77 ?  246  ASP A CG   1 
ATOM   3666  O OD1  . ASP A 1 280 ? -13.070 7.477   39.618 1.00 14.40 ?  246  ASP A OD1  1 
ATOM   3667  O OD2  . ASP A 1 280 ? -11.940 6.171   40.992 1.00 18.58 ?  246  ASP A OD2  1 
ATOM   3668  H H    . ASP A 1 280 ? -14.692 6.897   38.299 1.00 14.43 ?  246  ASP A H    1 
ATOM   3669  H HA   . ASP A 1 280 ? -16.147 5.464   40.077 1.00 15.68 ?  246  ASP A HA   1 
ATOM   3670  H HB2  . ASP A 1 280 ? -14.309 5.439   41.499 1.00 16.22 ?  246  ASP A HB2  1 
ATOM   3671  H HB3  . ASP A 1 280 ? -13.965 4.731   40.119 1.00 16.22 ?  246  ASP A HB3  1 
ATOM   3672  N N    A SER A 1 281 ? -16.523 8.339   39.957 0.53 13.77 ?  247  SER A N    1 
ATOM   3673  N N    B SER A 1 281 ? -16.516 8.342   39.957 0.47 13.77 ?  247  SER A N    1 
ATOM   3674  C CA   A SER A 1 281 ? -16.971 9.611   40.527 0.53 15.63 ?  247  SER A CA   1 
ATOM   3675  C CA   B SER A 1 281 ? -16.968 9.609   40.534 0.47 15.62 ?  247  SER A CA   1 
ATOM   3676  C C    A SER A 1 281 ? -18.497 9.613   40.543 0.53 14.54 ?  247  SER A C    1 
ATOM   3677  C C    B SER A 1 281 ? -18.494 9.612   40.544 0.47 14.55 ?  247  SER A C    1 
ATOM   3678  O O    A SER A 1 281 ? -19.147 10.029  39.582 0.53 15.15 ?  247  SER A O    1 
ATOM   3679  O O    B SER A 1 281 ? -19.141 10.028  39.581 0.47 15.15 ?  247  SER A O    1 
ATOM   3680  C CB   A SER A 1 281 ? -16.441 10.784  39.713 0.53 20.14 ?  247  SER A CB   1 
ATOM   3681  C CB   B SER A 1 281 ? -16.430 10.791  39.739 0.47 20.13 ?  247  SER A CB   1 
ATOM   3682  O OG   A SER A 1 281 ? -15.027 10.768  39.666 0.53 26.56 ?  247  SER A OG   1 
ATOM   3683  O OG   B SER A 1 281 ? -16.838 12.014  40.324 0.47 21.71 ?  247  SER A OG   1 
ATOM   3684  H H    A SER A 1 281 ? -16.693 8.267   39.117 0.53 16.53 ?  247  SER A H    1 
ATOM   3685  H H    B SER A 1 281 ? -16.679 8.276   39.115 0.47 16.52 ?  247  SER A H    1 
ATOM   3686  H HA   A SER A 1 281 ? -16.647 9.679   41.439 0.53 18.75 ?  247  SER A HA   1 
ATOM   3687  H HA   B SER A 1 281 ? -16.649 9.667   41.448 0.47 18.75 ?  247  SER A HA   1 
ATOM   3688  H HB2  A SER A 1 281 ? -16.787 10.722  38.809 0.53 24.17 ?  247  SER A HB2  1 
ATOM   3689  H HB2  B SER A 1 281 ? -15.461 10.753  39.731 0.47 24.16 ?  247  SER A HB2  1 
ATOM   3690  H HB3  A SER A 1 281 ? -16.734 11.612  40.124 0.53 24.17 ?  247  SER A HB3  1 
ATOM   3691  H HB3  B SER A 1 281 ? -16.771 10.745  38.832 0.47 24.16 ?  247  SER A HB3  1 
ATOM   3692  H HG   A SER A 1 281 ? -14.746 11.448  39.261 0.53 31.87 ?  247  SER A HG   1 
ATOM   3693  H HG   B SER A 1 281 ? -16.631 12.656  39.824 0.47 26.05 ?  247  SER A HG   1 
ATOM   3694  N N    . GLU A 1 282 ? -19.065 9.171   41.662 1.00 14.23 ?  248  GLU A N    1 
ATOM   3695  C CA   . GLU A 1 282 ? -20.505 9.010   41.750 1.00 14.47 ?  248  GLU A CA   1 
ATOM   3696  C C    . GLU A 1 282 ? -21.248 10.343  41.753 1.00 13.53 ?  248  GLU A C    1 
ATOM   3697  O O    . GLU A 1 282 ? -20.708 11.414  42.059 1.00 16.57 ?  248  GLU A O    1 
ATOM   3698  C CB   . GLU A 1 282 ? -20.874 8.151   42.967 1.00 15.69 ?  248  GLU A CB   1 
ATOM   3699  C CG   . GLU A 1 282 ? -20.734 8.818   44.332 1.00 18.77 ?  248  GLU A CG   1 
ATOM   3700  C CD   . GLU A 1 282 ? -19.320 8.779   44.900 1.00 20.45 ?  248  GLU A CD   1 
ATOM   3701  O OE1  . GLU A 1 282 ? -18.375 8.328   44.218 1.00 19.44 ?  248  GLU A OE1  1 
ATOM   3702  O OE2  . GLU A 1 282 ? -19.147 9.198   46.066 1.00 26.19 ?  248  GLU A OE2  1 
ATOM   3703  H H    . GLU A 1 282 ? -18.636 8.960   42.377 1.00 17.07 ?  248  GLU A H    1 
ATOM   3704  H HA   . GLU A 1 282 ? -20.813 8.546   40.957 1.00 17.37 ?  248  GLU A HA   1 
ATOM   3705  H HB2  . GLU A 1 282 ? -21.801 7.881   42.876 1.00 18.83 ?  248  GLU A HB2  1 
ATOM   3706  H HB3  . GLU A 1 282 ? -20.299 7.370   42.971 1.00 18.83 ?  248  GLU A HB3  1 
ATOM   3707  H HG2  . GLU A 1 282 ? -20.993 9.749   44.251 1.00 22.52 ?  248  GLU A HG2  1 
ATOM   3708  H HG3  . GLU A 1 282 ? -21.317 8.365   44.961 1.00 22.52 ?  248  GLU A HG3  1 
ATOM   3709  N N    . ALA A 1 283 ? -22.521 10.253  41.395 1.00 13.41 ?  249  ALA A N    1 
ATOM   3710  C CA   . ALA A 1 283 ? -23.420 11.389  41.298 1.00 14.28 ?  249  ALA A CA   1 
ATOM   3711  C C    . ALA A 1 283 ? -24.850 10.868  41.387 1.00 14.53 ?  249  ALA A C    1 
ATOM   3712  O O    . ALA A 1 283 ? -25.090 9.667   41.548 1.00 14.33 ?  249  ALA A O    1 
ATOM   3713  C CB   . ALA A 1 283 ? -23.178 12.157  39.993 1.00 16.90 ?  249  ALA A CB   1 
ATOM   3714  H H    . ALA A 1 283 ? -22.904 9.509   41.194 1.00 16.09 ?  249  ALA A H    1 
ATOM   3715  H HA   . ALA A 1 283 ? -23.268 11.991  42.044 1.00 17.13 ?  249  ALA A HA   1 
ATOM   3716  H HB1  . ALA A 1 283 ? -23.768 12.927  39.966 1.00 20.28 ?  249  ALA A HB1  1 
ATOM   3717  H HB2  . ALA A 1 283 ? -22.253 12.448  39.965 1.00 20.28 ?  249  ALA A HB2  1 
ATOM   3718  H HB3  . ALA A 1 283 ? -23.364 11.571  39.243 1.00 20.28 ?  249  ALA A HB3  1 
ATOM   3719  N N    . PHE A 1 284 ? -25.809 11.781  41.265 1.00 15.43 ?  250  PHE A N    1 
ATOM   3720  C CA   . PHE A 1 284 ? -27.224 11.439  41.156 1.00 16.37 ?  250  PHE A CA   1 
ATOM   3721  C C    . PHE A 1 284 ? -27.752 10.770  42.417 1.00 16.27 ?  250  PHE A C    1 
ATOM   3722  O O    . PHE A 1 284 ? -28.737 10.037  42.365 1.00 19.60 ?  250  PHE A O    1 
ATOM   3723  C CB   . PHE A 1 284 ? -27.518 10.569  39.923 1.00 14.96 ?  250  PHE A CB   1 
ATOM   3724  C CG   . PHE A 1 284 ? -26.620 10.861  38.747 1.00 13.32 ?  250  PHE A CG   1 
ATOM   3725  C CD1  . PHE A 1 284 ? -26.671 12.087  38.115 1.00 14.23 ?  250  PHE A CD1  1 
ATOM   3726  C CD2  . PHE A 1 284 ? -25.737 9.907   38.287 1.00 13.97 ?  250  PHE A CD2  1 
ATOM   3727  C CE1  . PHE A 1 284 ? -25.841 12.365  37.048 1.00 15.49 ?  250  PHE A CE1  1 
ATOM   3728  C CE2  . PHE A 1 284 ? -24.907 10.181  37.216 1.00 14.67 ?  250  PHE A CE2  1 
ATOM   3729  C CZ   . PHE A 1 284 ? -24.959 11.416  36.604 1.00 12.92 ?  250  PHE A CZ   1 
ATOM   3730  H H    . PHE A 1 284 ? -25.660 12.628  41.242 1.00 18.51 ?  250  PHE A H    1 
ATOM   3731  H HA   . PHE A 1 284 ? -27.715 12.267  41.040 1.00 19.64 ?  250  PHE A HA   1 
ATOM   3732  H HB2  . PHE A 1 284 ? -27.398 9.637   40.163 1.00 17.95 ?  250  PHE A HB2  1 
ATOM   3733  H HB3  . PHE A 1 284 ? -28.434 10.725  39.643 1.00 17.95 ?  250  PHE A HB3  1 
ATOM   3734  H HD1  . PHE A 1 284 ? -27.272 12.732  38.412 1.00 17.07 ?  250  PHE A HD1  1 
ATOM   3735  H HD2  . PHE A 1 284 ? -25.700 9.074   38.700 1.00 16.76 ?  250  PHE A HD2  1 
ATOM   3736  H HE1  . PHE A 1 284 ? -25.881 13.195  36.631 1.00 18.59 ?  250  PHE A HE1  1 
ATOM   3737  H HE2  . PHE A 1 284 ? -24.315 9.533   36.908 1.00 17.60 ?  250  PHE A HE2  1 
ATOM   3738  H HZ   . PHE A 1 284 ? -24.394 11.605  35.890 1.00 15.51 ?  250  PHE A HZ   1 
ATOM   3739  N N    . GLY A 1 285 ? -27.105 11.015  43.546 1.00 17.15 ?  251  GLY A N    1 
ATOM   3740  C CA   . GLY A 1 285 ? -27.474 10.356  44.780 1.00 19.60 ?  251  GLY A CA   1 
ATOM   3741  C C    . GLY A 1 285 ? -27.067 8.905   44.887 1.00 21.77 ?  251  GLY A C    1 
ATOM   3742  O O    . GLY A 1 285 ? -27.408 8.259   45.887 1.00 22.52 ?  251  GLY A O    1 
ATOM   3743  H H    . GLY A 1 285 ? -26.446 11.563  43.621 1.00 20.58 ?  251  GLY A H    1 
ATOM   3744  H HA2  . GLY A 1 285 ? -27.063 10.831  45.519 1.00 23.52 ?  251  GLY A HA2  1 
ATOM   3745  H HA3  . GLY A 1 285 ? -28.439 10.397  44.875 1.00 23.52 ?  251  GLY A HA3  1 
ATOM   3746  N N    . MET A 1 286 ? -26.365 8.359   43.898 1.00 17.32 ?  252  MET A N    1 
ATOM   3747  C CA   . MET A 1 286 ? -25.910 6.981   43.977 1.00 17.70 ?  252  MET A CA   1 
ATOM   3748  C C    . MET A 1 286 ? -24.705 6.876   44.896 1.00 16.77 ?  252  MET A C    1 
ATOM   3749  O O    . MET A 1 286 ? -23.879 7.783   44.981 1.00 18.07 ?  252  MET A O    1 
ATOM   3750  C CB   . MET A 1 286 ? -25.495 6.469   42.594 1.00 16.62 ?  252  MET A CB   1 
ATOM   3751  C CG   . MET A 1 286 ? -26.570 6.581   41.548 1.00 14.45 ?  252  MET A CG   1 
ATOM   3752  S SD   . MET A 1 286 ? -25.991 6.165   39.881 1.00 15.62 ?  252  MET A SD   1 
ATOM   3753  C CE   . MET A 1 286 ? -26.091 4.377   39.946 1.00 18.79 ?  252  MET A CE   1 
ATOM   3754  H H    . MET A 1 286 ? -26.141 8.767   43.175 1.00 20.79 ?  252  MET A H    1 
ATOM   3755  H HA   . MET A 1 286 ? -26.639 6.435   44.310 1.00 21.24 ?  252  MET A HA   1 
ATOM   3756  H HB2  . MET A 1 286 ? -24.732 6.983   42.288 1.00 19.94 ?  252  MET A HB2  1 
ATOM   3757  H HB3  . MET A 1 286 ? -25.255 5.532   42.669 1.00 19.94 ?  252  MET A HB3  1 
ATOM   3758  H HG2  . MET A 1 286 ? -27.293 5.974   41.773 1.00 17.34 ?  252  MET A HG2  1 
ATOM   3759  H HG3  . MET A 1 286 ? -26.898 7.494   41.531 1.00 17.34 ?  252  MET A HG3  1 
ATOM   3760  H HE1  . MET A 1 286 ? -25.779 4.013   39.103 1.00 22.55 ?  252  MET A HE1  1 
ATOM   3761  H HE2  . MET A 1 286 ? -25.533 4.056   40.672 1.00 22.55 ?  252  MET A HE2  1 
ATOM   3762  H HE3  . MET A 1 286 ? -27.013 4.118   40.097 1.00 22.55 ?  252  MET A HE3  1 
ATOM   3763  N N    . SER A 1 287 ? -24.606 5.754   45.592 1.00 15.54 ?  253  SER A N    1 
ATOM   3764  C CA   . SER A 1 287 ? -23.381 5.472   46.312 1.00 16.35 ?  253  SER A CA   1 
ATOM   3765  C C    . SER A 1 287 ? -22.256 5.176   45.323 1.00 16.18 ?  253  SER A C    1 
ATOM   3766  O O    . SER A 1 287 ? -22.485 4.812   44.167 1.00 15.68 ?  253  SER A O    1 
ATOM   3767  C CB   . SER A 1 287 ? -23.569 4.281   47.249 1.00 17.22 ?  253  SER A CB   1 
ATOM   3768  O OG   . SER A 1 287 ? -23.665 3.086   46.496 1.00 19.09 ?  253  SER A OG   1 
ATOM   3769  H H    . SER A 1 287 ? -25.220 5.156   45.661 1.00 18.65 ?  253  SER A H    1 
ATOM   3770  H HA   . SER A 1 287 ? -23.135 6.241   46.851 1.00 19.62 ?  253  SER A HA   1 
ATOM   3771  H HB2  . SER A 1 287 ? -22.807 4.221   47.847 1.00 20.67 ?  253  SER A HB2  1 
ATOM   3772  H HB3  . SER A 1 287 ? -24.383 4.402   47.762 1.00 20.67 ?  253  SER A HB3  1 
ATOM   3773  H HG   . SER A 1 287 ? -23.375 2.439   46.946 1.00 22.91 ?  253  SER A HG   1 
ATOM   3774  N N    . ASN A 1 288 ? -21.024 5.341   45.787 1.00 15.43 ?  254  ASN A N    1 
ATOM   3775  C CA   . ASN A 1 288 ? -19.877 4.998   44.957 1.00 16.52 ?  254  ASN A CA   1 
ATOM   3776  C C    . ASN A 1 288 ? -19.988 3.573   44.427 1.00 14.89 ?  254  ASN A C    1 
ATOM   3777  O O    . ASN A 1 288 ? -19.779 3.320   43.231 1.00 15.52 ?  254  ASN A O    1 
ATOM   3778  C CB   . ASN A 1 288 ? -18.586 5.195   45.749 1.00 17.86 ?  254  ASN A CB   1 
ATOM   3779  C CG   . ASN A 1 288 ? -17.350 4.902   44.930 1.00 18.20 ?  254  ASN A CG   1 
ATOM   3780  O OD1  . ASN A 1 288 ? -16.773 3.827   45.047 1.00 18.97 ?  254  ASN A OD1  1 
ATOM   3781  N ND2  . ASN A 1 288 ? -16.925 5.863   44.115 1.00 22.12 ?  254  ASN A ND2  1 
ATOM   3782  H H    . ASN A 1 288 ? -20.827 5.645   46.567 1.00 18.51 ?  254  ASN A H    1 
ATOM   3783  H HA   . ASN A 1 288 ? -19.848 5.594   44.192 1.00 19.83 ?  254  ASN A HA   1 
ATOM   3784  H HB2  . ASN A 1 288 ? -18.536 6.116   46.049 1.00 21.43 ?  254  ASN A HB2  1 
ATOM   3785  H HB3  . ASN A 1 288 ? -18.589 4.597   46.513 1.00 21.43 ?  254  ASN A HB3  1 
ATOM   3786  H HD21 . ASN A 1 288 ? -16.225 5.737   43.631 1.00 26.54 ?  254  ASN A HD21 1 
ATOM   3787  H HD22 . ASN A 1 288 ? -17.350 6.609   44.071 1.00 26.54 ?  254  ASN A HD22 1 
ATOM   3788  N N    . ALA A 1 289 ? -20.349 2.622   45.293 1.00 15.66 ?  255  ALA A N    1 
ATOM   3789  C CA   . ALA A 1 289 ? -20.449 1.235   44.853 1.00 14.17 ?  255  ALA A CA   1 
ATOM   3790  C C    . ALA A 1 289 ? -21.560 1.047   43.822 1.00 16.00 ?  255  ALA A C    1 
ATOM   3791  O O    . ALA A 1 289 ? -21.361 0.365   42.809 1.00 15.89 ?  255  ALA A O    1 
ATOM   3792  C CB   . ALA A 1 289 ? -20.660 0.317   46.062 1.00 18.58 ?  255  ALA A CB   1 
ATOM   3793  H H    . ALA A 1 289 ? -20.536 2.753   46.122 1.00 18.79 ?  255  ALA A H    1 
ATOM   3794  H HA   . ALA A 1 289 ? -19.614 0.983   44.428 1.00 17.01 ?  255  ALA A HA   1 
ATOM   3795  H HB1  . ALA A 1 289 ? -20.650 -0.606  45.763 1.00 22.29 ?  255  ALA A HB1  1 
ATOM   3796  H HB2  . ALA A 1 289 ? -19.945 0.466   46.700 1.00 22.29 ?  255  ALA A HB2  1 
ATOM   3797  H HB3  . ALA A 1 289 ? -21.515 0.524   46.470 1.00 22.29 ?  255  ALA A HB3  1 
ATOM   3798  N N    . GLU A 1 290 ? -22.733 1.640   44.050 1.00 14.38 ?  256  GLU A N    1 
ATOM   3799  C CA   . GLU A 1 290 ? -23.834 1.496   43.099 1.00 17.00 ?  256  GLU A CA   1 
ATOM   3800  C C    . GLU A 1 290 ? -23.447 2.051   41.730 1.00 13.99 ?  256  GLU A C    1 
ATOM   3801  O O    . GLU A 1 290 ? -23.764 1.460   40.695 1.00 14.28 ?  256  GLU A O    1 
ATOM   3802  C CB   . GLU A 1 290 ? -25.074 2.230   43.610 1.00 18.62 ?  256  GLU A CB   1 
ATOM   3803  C CG   . GLU A 1 290 ? -25.742 1.589   44.834 1.00 21.88 ?  256  GLU A CG   1 
ATOM   3804  C CD   . GLU A 1 290 ? -26.806 2.489   45.474 1.00 32.29 ?  256  GLU A CD   1 
ATOM   3805  O OE1  . GLU A 1 290 ? -26.735 3.740   45.343 1.00 23.84 ?  256  GLU A OE1  1 
ATOM   3806  O OE2  . GLU A 1 290 ? -27.713 1.935   46.137 1.00 35.14 ?  256  GLU A OE2  1 
ATOM   3807  H H    . GLU A 1 290 ? -22.915 2.124   44.738 1.00 17.26 ?  256  GLU A H    1 
ATOM   3808  H HA   . GLU A 1 290 ? -24.045 0.553   43.013 1.00 20.40 ?  256  GLU A HA   1 
ATOM   3809  H HB2  . GLU A 1 290 ? -24.817 3.133   43.857 1.00 22.34 ?  256  GLU A HB2  1 
ATOM   3810  H HB3  . GLU A 1 290 ? -25.732 2.256   42.898 1.00 22.34 ?  256  GLU A HB3  1 
ATOM   3811  H HG2  . GLU A 1 290 ? -26.172 0.764   44.561 1.00 26.25 ?  256  GLU A HG2  1 
ATOM   3812  H HG3  . GLU A 1 290 ? -25.064 1.405   45.502 1.00 26.25 ?  256  GLU A HG3  1 
ATOM   3813  N N    . TYR A 1 291 ? -22.794 3.214   41.718 1.00 14.43 ?  257  TYR A N    1 
ATOM   3814  C CA   . TYR A 1 291 ? -22.360 3.857   40.480 1.00 13.37 ?  257  TYR A CA   1 
ATOM   3815  C C    . TYR A 1 291 ? -21.343 2.999   39.735 1.00 11.67 ?  257  TYR A C    1 
ATOM   3816  O O    . TYR A 1 291 ? -21.467 2.810   38.520 1.00 12.36 ?  257  TYR A O    1 
ATOM   3817  C CB   . TYR A 1 291 ? -21.781 5.210   40.874 1.00 12.10 ?  257  TYR A CB   1 
ATOM   3818  C CG   . TYR A 1 291 ? -21.322 6.107   39.759 1.00 11.54 ?  257  TYR A CG   1 
ATOM   3819  C CD1  . TYR A 1 291 ? -20.015 6.054   39.303 1.00 13.73 ?  257  TYR A CD1  1 
ATOM   3820  C CD2  . TYR A 1 291 ? -22.174 7.034   39.195 1.00 14.03 ?  257  TYR A CD2  1 
ATOM   3821  C CE1  . TYR A 1 291 ? -19.581 6.886   38.319 1.00 12.60 ?  257  TYR A CE1  1 
ATOM   3822  C CE2  . TYR A 1 291 ? -21.740 7.875   38.195 1.00 12.92 ?  257  TYR A CE2  1 
ATOM   3823  C CZ   . TYR A 1 291 ? -20.444 7.788   37.767 1.00 13.09 ?  257  TYR A CZ   1 
ATOM   3824  O OH   . TYR A 1 291 ? -20.029 8.659   36.792 1.00 15.82 ?  257  TYR A OH   1 
ATOM   3825  H H    . TYR A 1 291 ? -22.587 3.659   42.425 1.00 17.32 ?  257  TYR A H    1 
ATOM   3826  H HA   . TYR A 1 291 ? -23.101 3.985   39.867 1.00 16.05 ?  257  TYR A HA   1 
ATOM   3827  H HB2  . TYR A 1 291 ? -22.463 5.696   41.364 1.00 14.52 ?  257  TYR A HB2  1 
ATOM   3828  H HB3  . TYR A 1 291 ? -21.013 5.052   41.444 1.00 14.52 ?  257  TYR A HB3  1 
ATOM   3829  H HD1  . TYR A 1 291 ? -19.425 5.440   39.676 1.00 16.48 ?  257  TYR A HD1  1 
ATOM   3830  H HD2  . TYR A 1 291 ? -23.053 7.091   39.493 1.00 16.84 ?  257  TYR A HD2  1 
ATOM   3831  H HE1  . TYR A 1 291 ? -18.700 6.841   38.023 1.00 15.11 ?  257  TYR A HE1  1 
ATOM   3832  H HE2  . TYR A 1 291 ? -22.321 8.495   37.816 1.00 15.50 ?  257  TYR A HE2  1 
ATOM   3833  H HH   . TYR A 1 291 ? -19.192 8.735   36.812 1.00 18.98 ?  257  TYR A HH   1 
ATOM   3834  N N    . LEU A 1 292 ? -20.362 2.438   40.447 1.00 12.53 ?  258  LEU A N    1 
ATOM   3835  C CA   . LEU A 1 292 ? -19.402 1.547   39.804 1.00 13.19 ?  258  LEU A CA   1 
ATOM   3836  C C    . LEU A 1 292 ? -20.067 0.268   39.296 1.00 13.27 ?  258  LEU A C    1 
ATOM   3837  O O    . LEU A 1 292 ? -19.696 -0.236  38.234 1.00 12.91 ?  258  LEU A O    1 
ATOM   3838  C CB   . LEU A 1 292 ? -18.241 1.243   40.749 1.00 12.27 ?  258  LEU A CB   1 
ATOM   3839  C CG   . LEU A 1 292 ? -17.107 2.261   40.643 1.00 13.46 ?  258  LEU A CG   1 
ATOM   3840  C CD1  . LEU A 1 292 ? -16.227 2.284   41.876 1.00 17.09 ?  258  LEU A CD1  1 
ATOM   3841  C CD2  . LEU A 1 292 ? -16.280 1.973   39.388 1.00 14.89 ?  258  LEU A CD2  1 
ATOM   3842  H H    . LEU A 1 292 ? -20.234 2.557   41.289 1.00 15.03 ?  258  LEU A H    1 
ATOM   3843  H HA   . LEU A 1 292 ? -19.031 2.000   39.030 1.00 15.83 ?  258  LEU A HA   1 
ATOM   3844  H HB2  . LEU A 1 292 ? -18.568 1.251   41.662 1.00 14.73 ?  258  LEU A HB2  1 
ATOM   3845  H HB3  . LEU A 1 292 ? -17.880 0.369   40.533 1.00 14.73 ?  258  LEU A HB3  1 
ATOM   3846  H HG   . LEU A 1 292 ? -17.496 3.147   40.577 1.00 16.16 ?  258  LEU A HG   1 
ATOM   3847  H HD11 . LEU A 1 292 ? -15.561 2.981   41.776 1.00 20.51 ?  258  LEU A HD11 1 
ATOM   3848  H HD12 . LEU A 1 292 ? -16.778 2.462   42.654 1.00 20.51 ?  258  LEU A HD12 1 
ATOM   3849  H HD13 . LEU A 1 292 ? -15.792 1.422   41.969 1.00 20.51 ?  258  LEU A HD13 1 
ATOM   3850  H HD21 . LEU A 1 292 ? -15.490 2.535   39.395 1.00 17.86 ?  258  LEU A HD21 1 
ATOM   3851  H HD22 . LEU A 1 292 ? -16.022 1.038   39.388 1.00 17.86 ?  258  LEU A HD22 1 
ATOM   3852  H HD23 . LEU A 1 292 ? -16.818 2.168   38.604 1.00 17.86 ?  258  LEU A HD23 1 
ATOM   3853  N N    . VAL A 1 293 ? -21.051 -0.282  40.019 1.00 12.60 ?  259  VAL A N    1 
ATOM   3854  C CA   . VAL A 1 293 ? -21.734 -1.479  39.518 1.00 13.38 ?  259  VAL A CA   1 
ATOM   3855  C C    . VAL A 1 293 ? -22.309 -1.214  38.131 1.00 12.77 ?  259  VAL A C    1 
ATOM   3856  O O    . VAL A 1 293 ? -22.159 -2.024  37.209 1.00 13.17 ?  259  VAL A O    1 
ATOM   3857  C CB   . VAL A 1 293 ? -22.817 -1.949  40.512 1.00 15.01 ?  259  VAL A CB   1 
ATOM   3858  C CG1  . VAL A 1 293 ? -23.817 -2.877  39.832 1.00 15.68 ?  259  VAL A CG1  1 
ATOM   3859  C CG2  . VAL A 1 293 ? -22.169 -2.614  41.719 1.00 17.34 ?  259  VAL A CG2  1 
ATOM   3860  H H    . VAL A 1 293 ? -21.333 0.009   40.778 1.00 15.12 ?  259  VAL A H    1 
ATOM   3861  H HA   . VAL A 1 293 ? -21.084 -2.195  39.440 1.00 16.05 ?  259  VAL A HA   1 
ATOM   3862  H HB   . VAL A 1 293 ? -23.314 -1.179  40.828 1.00 18.01 ?  259  VAL A HB   1 
ATOM   3863  H HG11 . VAL A 1 293 ? -24.341 -3.330  40.511 1.00 18.82 ?  259  VAL A HG11 1 
ATOM   3864  H HG12 . VAL A 1 293 ? -24.400 -2.350  39.262 1.00 18.82 ?  259  VAL A HG12 1 
ATOM   3865  H HG13 . VAL A 1 293 ? -23.334 -3.527  39.298 1.00 18.82 ?  259  VAL A HG13 1 
ATOM   3866  H HG21 . VAL A 1 293 ? -22.863 -2.881  42.342 1.00 20.80 ?  259  VAL A HG21 1 
ATOM   3867  H HG22 . VAL A 1 293 ? -21.673 -3.392  41.422 1.00 20.80 ?  259  VAL A HG22 1 
ATOM   3868  H HG23 . VAL A 1 293 ? -21.569 -1.981  42.143 1.00 20.80 ?  259  VAL A HG23 1 
ATOM   3869  N N    . GLU A 1 294 ? -22.968 -0.069  37.957 1.00 11.50 ?  260  GLU A N    1 
ATOM   3870  C CA   . GLU A 1 294 ? -23.566 0.241   36.661 1.00 11.84 ?  260  GLU A CA   1 
ATOM   3871  C C    . GLU A 1 294 ? -22.495 0.483   35.601 1.00 12.90 ?  260  GLU A C    1 
ATOM   3872  O O    . GLU A 1 294 ? -22.647 0.061   34.446 1.00 12.02 ?  260  GLU A O    1 
ATOM   3873  C CB   . GLU A 1 294 ? -24.482 1.448   36.793 1.00 12.72 ?  260  GLU A CB   1 
ATOM   3874  C CG   . GLU A 1 294 ? -25.838 1.108   37.441 1.00 14.39 ?  260  GLU A CG   1 
ATOM   3875  C CD   . GLU A 1 294 ? -26.911 2.146   37.175 1.00 18.87 ?  260  GLU A CD   1 
ATOM   3876  O OE1  . GLU A 1 294 ? -26.779 2.969   36.241 1.00 14.75 ?  260  GLU A OE1  1 
ATOM   3877  O OE2  . GLU A 1 294 ? -27.939 2.116   37.890 1.00 20.74 ?  260  GLU A OE2  1 
ATOM   3878  H H    . GLU A 1 294 ? -23.082 0.533   38.560 1.00 13.80 ?  260  GLU A H    1 
ATOM   3879  H HA   . GLU A 1 294 ? -24.104 -0.512  36.371 1.00 14.21 ?  260  GLU A HA   1 
ATOM   3880  H HB2  . GLU A 1 294 ? -24.046 2.115   37.346 1.00 15.26 ?  260  GLU A HB2  1 
ATOM   3881  H HB3  . GLU A 1 294 ? -24.655 1.809   35.910 1.00 15.26 ?  260  GLU A HB3  1 
ATOM   3882  H HG2  . GLU A 1 294 ? -26.150 0.260   37.089 1.00 17.26 ?  260  GLU A HG2  1 
ATOM   3883  H HG3  . GLU A 1 294 ? -25.719 1.044   38.402 1.00 17.26 ?  260  GLU A HG3  1 
ATOM   3884  N N    . GLY A 1 295 ? -21.410 1.166   35.962 1.00 11.14 ?  261  GLY A N    1 
ATOM   3885  C CA   . GLY A 1 295 ? -20.359 1.405   34.986 1.00 13.00 ?  261  GLY A CA   1 
ATOM   3886  C C    . GLY A 1 295 ? -19.676 0.121   34.556 1.00 10.95 ?  261  GLY A C    1 
ATOM   3887  O O    . GLY A 1 295 ? -19.350 -0.060  33.382 1.00 10.79 ?  261  GLY A O    1 
ATOM   3888  H H    . GLY A 1 295 ? -21.265 1.493   36.744 1.00 13.36 ?  261  GLY A H    1 
ATOM   3889  H HA2  . GLY A 1 295 ? -20.739 1.828   34.200 1.00 15.60 ?  261  GLY A HA2  1 
ATOM   3890  H HA3  . GLY A 1 295 ? -19.691 1.994   35.370 1.00 15.60 ?  261  GLY A HA3  1 
ATOM   3891  N N    . ILE A 1 296 ? -19.455 -0.786  35.503 1.00 11.22 ?  262  ILE A N    1 
ATOM   3892  C CA   . ILE A 1 296 ? -18.846 -2.076  35.191 1.00 11.65 ?  262  ILE A CA   1 
ATOM   3893  C C    . ILE A 1 296 ? -19.734 -2.866  34.230 1.00 11.40 ?  262  ILE A C    1 
ATOM   3894  O O    . ILE A 1 296 ? -19.256 -3.458  33.255 1.00 11.45 ?  262  ILE A O    1 
ATOM   3895  C CB   . ILE A 1 296 ? -18.569 -2.849  36.499 1.00 12.32 ?  262  ILE A CB   1 
ATOM   3896  C CG1  . ILE A 1 296 ? -17.372 -2.227  37.230 1.00 11.73 ?  262  ILE A CG1  1 
ATOM   3897  C CG2  . ILE A 1 296 ? -18.359 -4.326  36.237 1.00 11.33 ?  262  ILE A CG2  1 
ATOM   3898  C CD1  . ILE A 1 296 ? -17.234 -2.664  38.683 1.00 13.82 ?  262  ILE A CD1  1 
ATOM   3899  H H    . ILE A 1 296 ? -19.648 -0.681  36.335 1.00 13.47 ?  262  ILE A H    1 
ATOM   3900  H HA   . ILE A 1 296 ? -17.999 -1.930  34.743 1.00 13.99 ?  262  ILE A HA   1 
ATOM   3901  H HB   . ILE A 1 296 ? -19.349 -2.773  37.070 1.00 14.78 ?  262  ILE A HB   1 
ATOM   3902  H HG12 . ILE A 1 296 ? -16.559 -2.482  36.767 1.00 14.07 ?  262  ILE A HG12 1 
ATOM   3903  H HG13 . ILE A 1 296 ? -17.470 -1.262  37.221 1.00 14.07 ?  262  ILE A HG13 1 
ATOM   3904  H HG21 . ILE A 1 296 ? -18.084 -4.757  37.061 1.00 13.60 ?  262  ILE A HG21 1 
ATOM   3905  H HG22 . ILE A 1 296 ? -19.191 -4.712  35.922 1.00 13.60 ?  262  ILE A HG22 1 
ATOM   3906  H HG23 . ILE A 1 296 ? -17.669 -4.432  35.563 1.00 13.60 ?  262  ILE A HG23 1 
ATOM   3907  H HD11 . ILE A 1 296 ? -16.427 -2.275  39.054 1.00 16.58 ?  262  ILE A HD11 1 
ATOM   3908  H HD12 . ILE A 1 296 ? -18.009 -2.357  39.180 1.00 16.58 ?  262  ILE A HD12 1 
ATOM   3909  H HD13 . ILE A 1 296 ? -17.181 -3.632  38.717 1.00 16.58 ?  262  ILE A HD13 1 
ATOM   3910  N N    . GLU A 1 297 ? -21.036 -2.902  34.499 1.00 11.19 ?  263  GLU A N    1 
ATOM   3911  C CA   . GLU A 1 297 ? -21.945 -3.630  33.618 1.00 11.88 ?  263  GLU A CA   1 
ATOM   3912  C C    . GLU A 1 297 ? -21.899 -3.076  32.199 1.00 12.49 ?  263  GLU A C    1 
ATOM   3913  O O    . GLU A 1 297 ? -21.834 -3.832  31.219 1.00 12.41 ?  263  GLU A O    1 
ATOM   3914  C CB   . GLU A 1 297 ? -23.364 -3.544  34.194 1.00 13.55 ?  263  GLU A CB   1 
ATOM   3915  C CG   . GLU A 1 297 ? -24.497 -4.013  33.294 1.00 24.83 ?  263  GLU A CG   1 
ATOM   3916  C CD   . GLU A 1 297 ? -24.319 -5.426  32.804 1.00 32.96 ?  263  GLU A CD   1 
ATOM   3917  O OE1  . GLU A 1 297 ? -23.775 -6.254  33.560 1.00 36.60 ?  263  GLU A OE1  1 
ATOM   3918  O OE2  . GLU A 1 297 ? -24.752 -5.709  31.665 1.00 43.57 ?  263  GLU A OE2  1 
ATOM   3919  H H    . GLU A 1 297 ? -21.413 -2.521  35.171 1.00 13.43 ?  263  GLU A H    1 
ATOM   3920  H HA   . GLU A 1 297 ? -21.680 -4.563  33.575 1.00 14.26 ?  263  GLU A HA   1 
ATOM   3921  H HB2  . GLU A 1 297 ? -23.396 -4.087  34.997 1.00 16.26 ?  263  GLU A HB2  1 
ATOM   3922  H HB3  . GLU A 1 297 ? -23.543 -2.616  34.414 1.00 16.26 ?  263  GLU A HB3  1 
ATOM   3923  H HG2  . GLU A 1 297 ? -25.330 -3.972  33.789 1.00 29.80 ?  263  GLU A HG2  1 
ATOM   3924  H HG3  . GLU A 1 297 ? -24.544 -3.433  32.518 1.00 29.80 ?  263  GLU A HG3  1 
ATOM   3925  N N    . ALA A 1 298 ? -21.962 -1.748  32.060 1.00 11.27 ?  264  ALA A N    1 
ATOM   3926  C CA   . ALA A 1 298 ? -21.930 -1.146  30.728 1.00 9.34  ?  264  ALA A CA   1 
ATOM   3927  C C    . ALA A 1 298 ? -20.633 -1.480  30.004 1.00 9.72  ?  264  ALA A C    1 
ATOM   3928  O O    . ALA A 1 298 ? -20.643 -1.807  28.806 1.00 10.30 ?  264  ALA A O    1 
ATOM   3929  C CB   . ALA A 1 298 ? -22.090 0.365   30.858 1.00 12.02 ?  264  ALA A CB   1 
ATOM   3930  H H    . ALA A 1 298 ? -22.021 -1.186  32.708 1.00 13.52 ?  264  ALA A H    1 
ATOM   3931  H HA   . ALA A 1 298 ? -22.666 -1.494  30.200 1.00 11.21 ?  264  ALA A HA   1 
ATOM   3932  H HB1  . ALA A 1 298 ? -22.086 0.761   29.973 1.00 14.43 ?  264  ALA A HB1  1 
ATOM   3933  H HB2  . ALA A 1 298 ? -22.931 0.557   31.302 1.00 14.43 ?  264  ALA A HB2  1 
ATOM   3934  H HB3  . ALA A 1 298 ? -21.352 0.717   31.381 1.00 14.43 ?  264  ALA A HB3  1 
ATOM   3935  N N    . THR A 1 299 ? -19.507 -1.386  30.716 1.00 10.38 ?  265  THR A N    1 
ATOM   3936  C CA   . THR A 1 299 ? -18.203 -1.618  30.106 1.00 9.83  ?  265  THR A CA   1 
ATOM   3937  C C    . THR A 1 299 ? -18.042 -3.076  29.696 1.00 11.24 ?  265  THR A C    1 
ATOM   3938  O O    . THR A 1 299 ? -17.530 -3.359  28.612 1.00 10.14 ?  265  THR A O    1 
ATOM   3939  C CB   . THR A 1 299 ? -17.094 -1.189  31.077 1.00 10.57 ?  265  THR A CB   1 
ATOM   3940  O OG1  . THR A 1 299 ? -17.279 0.187   31.456 1.00 10.64 ?  265  THR A OG1  1 
ATOM   3941  C CG2  . THR A 1 299 ? -15.719 -1.314  30.448 1.00 9.28  ?  265  THR A CG2  1 
ATOM   3942  H H    . THR A 1 299 ? -19.473 -1.188  31.552 1.00 12.45 ?  265  THR A H    1 
ATOM   3943  H HA   . THR A 1 299 ? -18.121 -1.078  29.305 1.00 11.80 ?  265  THR A HA   1 
ATOM   3944  H HB   . THR A 1 299 ? -17.136 -1.768  31.855 1.00 12.69 ?  265  THR A HB   1 
ATOM   3945  H HG1  . THR A 1 299 ? -17.999 0.274   31.879 1.00 12.77 ?  265  THR A HG1  1 
ATOM   3946  H HG21 . THR A 1 299 ? -15.039 -1.021  31.075 1.00 11.13 ?  265  THR A HG21 1 
ATOM   3947  H HG22 . THR A 1 299 ? -15.547 -2.238  30.207 1.00 11.13 ?  265  THR A HG22 1 
ATOM   3948  H HG23 . THR A 1 299 ? -15.668 -0.766  29.649 1.00 11.13 ?  265  THR A HG23 1 
ATOM   3949  N N    . GLN A 1 300 ? -18.433 -4.005  30.572 1.00 10.84 ?  266  GLN A N    1 
ATOM   3950  C CA   . GLN A 1 300 ? -18.410 -5.426  30.228 1.00 10.50 ?  266  GLN A CA   1 
ATOM   3951  C C    . GLN A 1 300 ? -19.195 -5.687  28.952 1.00 10.88 ?  266  GLN A C    1 
ATOM   3952  O O    . GLN A 1 300 ? -18.717 -6.381  28.049 1.00 10.38 ?  266  GLN A O    1 
ATOM   3953  C CB   . GLN A 1 300 ? -18.976 -6.263  31.381 1.00 11.52 ?  266  GLN A CB   1 
ATOM   3954  C CG   . GLN A 1 300 ? -18.039 -6.380  32.565 1.00 11.80 ?  266  GLN A CG   1 
ATOM   3955  C CD   . GLN A 1 300 ? -18.701 -6.986  33.776 1.00 10.91 ?  266  GLN A CD   1 
ATOM   3956  O OE1  . GLN A 1 300 ? -19.936 -7.010  33.891 1.00 13.07 ?  266  GLN A OE1  1 
ATOM   3957  N NE2  . GLN A 1 300 ? -17.878 -7.490  34.695 1.00 12.39 ?  266  GLN A NE2  1 
ATOM   3958  H H    . GLN A 1 300 ? -18.714 -3.840  31.367 1.00 13.01 ?  266  GLN A H    1 
ATOM   3959  H HA   . GLN A 1 300 ? -17.489 -5.696  30.086 1.00 12.60 ?  266  GLN A HA   1 
ATOM   3960  H HB2  . GLN A 1 300 ? -19.797 -5.850  31.692 1.00 13.82 ?  266  GLN A HB2  1 
ATOM   3961  H HB3  . GLN A 1 300 ? -19.157 -7.158  31.056 1.00 13.82 ?  266  GLN A HB3  1 
ATOM   3962  H HG2  . GLN A 1 300 ? -17.289 -6.944  32.320 1.00 14.16 ?  266  GLN A HG2  1 
ATOM   3963  H HG3  . GLN A 1 300 ? -17.723 -5.496  32.808 1.00 14.16 ?  266  GLN A HG3  1 
ATOM   3964  H HE21 . GLN A 1 300 ? -17.027 -7.456  34.575 1.00 14.86 ?  266  GLN A HE21 1 
ATOM   3965  H HE22 . GLN A 1 300 ? -18.198 -7.849  35.408 1.00 14.86 ?  266  GLN A HE22 1 
ATOM   3966  N N    . LYS A 1 301 ? -20.405 -5.135  28.859 1.00 9.73  ?  267  LYS A N    1 
ATOM   3967  C CA   . LYS A 1 301 ? -21.223 -5.373  27.675 1.00 10.08 ?  267  LYS A CA   1 
ATOM   3968  C C    . LYS A 1 301 ? -20.564 -4.798  26.429 1.00 11.78 ?  267  LYS A C    1 
ATOM   3969  O O    . LYS A 1 301 ? -20.509 -5.456  25.386 1.00 11.84 ?  267  LYS A O    1 
ATOM   3970  C CB   . LYS A 1 301 ? -22.622 -4.808  27.876 1.00 12.59 ?  267  LYS A CB   1 
ATOM   3971  C CG   . LYS A 1 301 ? -23.464 -5.599  28.862 1.00 19.22 ?  267  LYS A CG   1 
ATOM   3972  C CD   . LYS A 1 301 ? -23.493 -7.115  28.543 1.00 33.77 ?  267  LYS A CD   1 
ATOM   3973  C CE   . LYS A 1 301 ? -23.729 -7.987  29.782 1.00 41.00 ?  267  LYS A CE   1 
ATOM   3974  N NZ   . LYS A 1 301 ? -22.546 -8.879  30.035 1.00 38.42 ?  267  LYS A NZ   1 
ATOM   3975  H H    . LYS A 1 301 ? -20.766 -4.630  29.454 1.00 11.68 ?  267  LYS A H    1 
ATOM   3976  H HA   . LYS A 1 301 ? -21.316 -6.329  27.543 1.00 12.09 ?  267  LYS A HA   1 
ATOM   3977  H HB2  . LYS A 1 301 ? -22.547 -3.901  28.211 1.00 15.11 ?  267  LYS A HB2  1 
ATOM   3978  H HB3  . LYS A 1 301 ? -23.085 -4.810  27.024 1.00 15.11 ?  267  LYS A HB3  1 
ATOM   3979  H HG2  . LYS A 1 301 ? -23.096 -5.487  29.753 1.00 23.06 ?  267  LYS A HG2  1 
ATOM   3980  H HG3  . LYS A 1 301 ? -24.375 -5.269  28.836 1.00 23.06 ?  267  LYS A HG3  1 
ATOM   3981  H HD2  . LYS A 1 301 ? -24.210 -7.290  27.914 1.00 40.52 ?  267  LYS A HD2  1 
ATOM   3982  H HD3  . LYS A 1 301 ? -22.641 -7.371  28.156 1.00 40.52 ?  267  LYS A HD3  1 
ATOM   3983  H HE2  . LYS A 1 301 ? -23.860 -7.420  30.558 1.00 49.19 ?  267  LYS A HE2  1 
ATOM   3984  H HE3  . LYS A 1 301 ? -24.511 -8.544  29.642 1.00 49.19 ?  267  LYS A HE3  1 
ATOM   3985  H HZ1  . LYS A 1 301 ? -22.702 -9.397  30.742 1.00 46.10 ?  267  LYS A HZ1  1 
ATOM   3986  H HZ2  . LYS A 1 301 ? -22.397 -9.395  29.326 1.00 46.10 ?  267  LYS A HZ2  1 
ATOM   3987  H HZ3  . LYS A 1 301 ? -21.822 -8.386  30.192 1.00 46.10 ?  267  LYS A HZ3  1 
ATOM   3988  N N    . ALA A 1 302 ? -20.042 -3.577  26.518 1.00 9.91  ?  268  ALA A N    1 
ATOM   3989  C CA   . ALA A 1 302 ? -19.389 -2.967  25.369 1.00 9.94  ?  268  ALA A CA   1 
ATOM   3990  C C    . ALA A 1 302 ? -18.157 -3.760  24.948 1.00 9.84  ?  268  ALA A C    1 
ATOM   3991  O O    . ALA A 1 302 ? -17.964 -4.043  23.761 1.00 9.89  ?  268  ALA A O    1 
ATOM   3992  C CB   . ALA A 1 302 ? -19.022 -1.525  25.721 1.00 10.83 ?  268  ALA A CB   1 
ATOM   3993  H H    . ALA A 1 302 ? -20.053 -3.087  27.225 1.00 11.89 ?  268  ALA A H    1 
ATOM   3994  H HA   . ALA A 1 302 ? -19.997 -2.958  24.613 1.00 11.93 ?  268  ALA A HA   1 
ATOM   3995  H HB1  . ALA A 1 302 ? -18.690 -1.080  24.926 1.00 12.99 ?  268  ALA A HB1  1 
ATOM   3996  H HB2  . ALA A 1 302 ? -19.813 -1.069  26.049 1.00 12.99 ?  268  ALA A HB2  1 
ATOM   3997  H HB3  . ALA A 1 302 ? -18.337 -1.532  26.407 1.00 12.99 ?  268  ALA A HB3  1 
ATOM   3998  N N    . ALA A 1 303 ? -17.301 -4.108  25.909 1.00 9.87  ?  269  ALA A N    1 
ATOM   3999  C CA   . ALA A 1 303 ? -16.088 -4.856  25.591 1.00 9.61  ?  269  ALA A CA   1 
ATOM   4000  C C    . ALA A 1 303 ? -16.425 -6.216  24.984 1.00 9.83  ?  269  ALA A C    1 
ATOM   4001  O O    . ALA A 1 303 ? -15.770 -6.654  24.029 1.00 10.19 ?  269  ALA A O    1 
ATOM   4002  C CB   . ALA A 1 303 ? -15.228 -5.021  26.843 1.00 10.00 ?  269  ALA A CB   1 
ATOM   4003  H H    . ALA A 1 303 ? -17.398 -3.926  26.744 1.00 11.84 ?  269  ALA A H    1 
ATOM   4004  H HA   . ALA A 1 303 ? -15.573 -4.355  24.939 1.00 11.53 ?  269  ALA A HA   1 
ATOM   4005  H HB1  . ALA A 1 303 ? -14.369 -5.394  26.589 1.00 12.01 ?  269  ALA A HB1  1 
ATOM   4006  H HB2  . ALA A 1 303 ? -15.102 -4.152  27.256 1.00 12.01 ?  269  ALA A HB2  1 
ATOM   4007  H HB3  . ALA A 1 303 ? -15.679 -5.618  27.459 1.00 12.01 ?  269  ALA A HB3  1 
ATOM   4008  N N    . GLN A 1 304 ? -17.430 -6.894  25.532 1.00 9.87  ?  270  GLN A N    1 
ATOM   4009  C CA   . GLN A 1 304 ? -17.801 -8.210  25.017 1.00 10.67 ?  270  GLN A CA   1 
ATOM   4010  C C    . GLN A 1 304 ? -18.415 -8.120  23.630 1.00 13.74 ?  270  GLN A C    1 
ATOM   4011  O O    . GLN A 1 304 ? -18.411 -9.118  22.895 1.00 13.23 ?  270  GLN A O    1 
ATOM   4012  C CB   . GLN A 1 304 ? -18.748 -8.872  26.017 1.00 11.70 ?  270  GLN A CB   1 
ATOM   4013  C CG   . GLN A 1 304 ? -18.051 -9.310  27.310 1.00 12.57 ?  270  GLN A CG   1 
ATOM   4014  C CD   . GLN A 1 304 ? -19.002 -9.618  28.456 1.00 14.06 ?  270  GLN A CD   1 
ATOM   4015  O OE1  . GLN A 1 304 ? -20.157 -9.976  28.240 1.00 18.60 ?  270  GLN A OE1  1 
ATOM   4016  N NE2  . GLN A 1 304 ? -18.513 -9.504  29.681 1.00 13.28 ?  270  GLN A NE2  1 
ATOM   4017  H H    . GLN A 1 304 ? -17.907 -6.619  26.193 1.00 11.85 ?  270  GLN A H    1 
ATOM   4018  H HA   . GLN A 1 304 ? -17.020 -8.780  24.933 1.00 12.80 ?  270  GLN A HA   1 
ATOM   4019  H HB2  . GLN A 1 304 ? -19.446 -8.242  26.253 1.00 14.05 ?  270  GLN A HB2  1 
ATOM   4020  H HB3  . GLN A 1 304 ? -19.137 -9.660  25.607 1.00 14.05 ?  270  GLN A HB3  1 
ATOM   4021  H HG2  . GLN A 1 304 ? -17.538 -10.113 27.130 1.00 15.08 ?  270  GLN A HG2  1 
ATOM   4022  H HG3  . GLN A 1 304 ? -17.461 -8.597  27.602 1.00 15.08 ?  270  GLN A HG3  1 
ATOM   4023  H HE21 . GLN A 1 304 ? -17.695 -9.265  29.797 1.00 15.93 ?  270  GLN A HE21 1 
ATOM   4024  H HE22 . GLN A 1 304 ? -19.014 -9.668  30.361 1.00 15.93 ?  270  GLN A HE22 1 
ATOM   4025  N N    . SER A 1 305 ? -18.922 -6.950  23.245 1.00 12.65 ?  271  SER A N    1 
ATOM   4026  C CA   . SER A 1 305 ? -19.411 -6.728  21.889 1.00 11.96 ?  271  SER A CA   1 
ATOM   4027  C C    . SER A 1 305 ? -18.290 -6.449  20.891 1.00 12.46 ?  271  SER A C    1 
ATOM   4028  O O    . SER A 1 305 ? -18.572 -6.269  19.704 1.00 12.99 ?  271  SER A O    1 
ATOM   4029  C CB   . SER A 1 305 ? -20.470 -5.621  21.860 1.00 14.27 ?  271  SER A CB   1 
ATOM   4030  O OG   . SER A 1 305 ? -19.908 -4.316  21.923 1.00 14.54 ?  271  SER A OG   1 
ATOM   4031  H H    . SER A 1 305 ? -18.993 -6.263  23.758 1.00 15.18 ?  271  SER A H    1 
ATOM   4032  H HA   . SER A 1 305 ? -19.861 -7.533  21.590 1.00 14.35 ?  271  SER A HA   1 
ATOM   4033  H HB2  . SER A 1 305 ? -20.974 -5.700  21.034 1.00 17.13 ?  271  SER A HB2  1 
ATOM   4034  H HB3  . SER A 1 305 ? -21.059 -5.740  22.621 1.00 17.13 ?  271  SER A HB3  1 
ATOM   4035  H HG   . SER A 1 305 ? -19.371 -4.265  22.567 1.00 17.45 ?  271  SER A HG   1 
ATOM   4036  N N    . GLY A 1 306 ? -17.030 -6.390  21.322 1.00 10.66 ?  272  GLY A N    1 
ATOM   4037  C CA   . GLY A 1 306 ? -15.932 -6.160  20.407 1.00 11.17 ?  272  GLY A CA   1 
ATOM   4038  C C    . GLY A 1 306 ? -15.519 -4.712  20.236 1.00 9.30  ?  272  GLY A C    1 
ATOM   4039  O O    . GLY A 1 306 ? -14.691 -4.424  19.369 1.00 10.09 ?  272  GLY A O    1 
ATOM   4040  H H    . GLY A 1 306 ? -16.792 -6.482  22.143 1.00 12.79 ?  272  GLY A H    1 
ATOM   4041  H HA2  . GLY A 1 306 ? -15.157 -6.650  20.725 1.00 13.41 ?  272  GLY A HA2  1 
ATOM   4042  H HA3  . GLY A 1 306 ? -16.182 -6.498  19.533 1.00 13.41 ?  272  GLY A HA3  1 
ATOM   4043  N N    . LYS A 1 307 ? -16.050 -3.810  21.057 1.00 10.36 ?  273  LYS A N    1 
ATOM   4044  C CA   . LYS A 1 307 ? -15.685 -2.395  21.016 1.00 8.64  ?  273  LYS A CA   1 
ATOM   4045  C C    . LYS A 1 307 ? -14.405 -2.167  21.799 1.00 8.52  ?  273  LYS A C    1 
ATOM   4046  O O    . LYS A 1 307 ? -14.167 -2.801  22.825 1.00 9.24  ?  273  LYS A O    1 
ATOM   4047  C CB   . LYS A 1 307 ? -16.802 -1.547  21.626 1.00 10.22 ?  273  LYS A CB   1 
ATOM   4048  C CG   . LYS A 1 307 ? -18.136 -1.627  20.911 1.00 11.31 ?  273  LYS A CG   1 
ATOM   4049  C CD   . LYS A 1 307 ? -18.195 -0.787  19.669 1.00 14.72 ?  273  LYS A CD   1 
ATOM   4050  C CE   . LYS A 1 307 ? -19.603 -0.878  19.044 1.00 14.64 ?  273  LYS A CE   1 
ATOM   4051  N NZ   . LYS A 1 307 ? -19.808 0.009   17.881 1.00 15.18 ?  273  LYS A NZ   1 
ATOM   4052  H H    . LYS A 1 307 ? -16.636 -3.995  21.659 1.00 12.43 ?  273  LYS A H    1 
ATOM   4053  H HA   . LYS A 1 307 ? -15.549 -2.121  20.096 1.00 10.36 ?  273  LYS A HA   1 
ATOM   4054  H HB2  . LYS A 1 307 ? -16.944 -1.840  22.540 1.00 12.27 ?  273  LYS A HB2  1 
ATOM   4055  H HB3  . LYS A 1 307 ? -16.522 -0.618  21.615 1.00 12.27 ?  273  LYS A HB3  1 
ATOM   4056  H HG2  . LYS A 1 307 ? -18.301 -2.548  20.656 1.00 13.57 ?  273  LYS A HG2  1 
ATOM   4057  H HG3  . LYS A 1 307 ? -18.833 -1.319  21.512 1.00 13.57 ?  273  LYS A HG3  1 
ATOM   4058  H HD2  . LYS A 1 307 ? -18.011 0.139   19.890 1.00 17.66 ?  273  LYS A HD2  1 
ATOM   4059  H HD3  . LYS A 1 307 ? -17.546 -1.110  19.024 1.00 17.66 ?  273  LYS A HD3  1 
ATOM   4060  H HE2  . LYS A 1 307 ? -19.753 -1.790  18.748 1.00 17.57 ?  273  LYS A HE2  1 
ATOM   4061  H HE3  . LYS A 1 307 ? -20.257 -0.636  19.717 1.00 17.57 ?  273  LYS A HE3  1 
ATOM   4062  H HZ1  . LYS A 1 307 ? -19.697 0.859   18.123 1.00 18.22 ?  273  LYS A HZ1  1 
ATOM   4063  H HZ2  . LYS A 1 307 ? -19.221 -0.188  17.241 1.00 18.22 ?  273  LYS A HZ2  1 
ATOM   4064  H HZ3  . LYS A 1 307 ? -20.631 -0.095  17.560 1.00 18.22 ?  273  LYS A HZ3  1 
ATOM   4065  N N    . ILE A 1 308 ? -13.580 -1.251  21.294 1.00 7.50  ?  274  ILE A N    1 
ATOM   4066  C CA   . ILE A 1 308 ? -12.413 -0.790  22.031 1.00 8.63  ?  274  ILE A CA   1 
ATOM   4067  C C    . ILE A 1 308 ? -12.871 -0.067  23.282 1.00 7.41  ?  274  ILE A C    1 
ATOM   4068  O O    . ILE A 1 308 ? -13.869 0.670   23.269 1.00 8.46  ?  274  ILE A O    1 
ATOM   4069  C CB   . ILE A 1 308 ? -11.581 0.163   21.157 1.00 8.71  ?  274  ILE A CB   1 
ATOM   4070  C CG1  . ILE A 1 308 ? -11.042 -0.555  19.916 1.00 9.82  ?  274  ILE A CG1  1 
ATOM   4071  C CG2  . ILE A 1 308 ? -10.433 0.761   21.960 1.00 8.66  ?  274  ILE A CG2  1 
ATOM   4072  C CD1  . ILE A 1 308 ? -10.519 0.382   18.841 1.00 11.52 ?  274  ILE A CD1  1 
ATOM   4073  H H    . ILE A 1 308 ? -13.675 -0.880  20.524 1.00 9.01  ?  274  ILE A H    1 
ATOM   4074  H HA   . ILE A 1 308 ? -11.870 -1.556  22.276 1.00 10.35 ?  274  ILE A HA   1 
ATOM   4075  H HB   . ILE A 1 308 ? -12.166 0.879   20.863 1.00 10.46 ?  274  ILE A HB   1 
ATOM   4076  H HG12 . ILE A 1 308 ? -10.311 -1.134  20.184 1.00 11.79 ?  274  ILE A HG12 1 
ATOM   4077  H HG13 . ILE A 1 308 ? -11.756 -1.082  19.526 1.00 11.79 ?  274  ILE A HG13 1 
ATOM   4078  H HG21 . ILE A 1 308 ? -9.809  1.186   21.351 1.00 10.39 ?  274  ILE A HG21 1 
ATOM   4079  H HG22 . ILE A 1 308 ? -10.789 1.418   22.579 1.00 10.39 ?  274  ILE A HG22 1 
ATOM   4080  H HG23 . ILE A 1 308 ? -9.987  0.053   22.450 1.00 10.39 ?  274  ILE A HG23 1 
ATOM   4081  H HD11 . ILE A 1 308 ? -10.409 -0.114  18.015 1.00 13.82 ?  274  ILE A HD11 1 
ATOM   4082  H HD12 . ILE A 1 308 ? -11.157 1.102   18.712 1.00 13.82 ?  274  ILE A HD12 1 
ATOM   4083  H HD13 . ILE A 1 308 ? -9.665  0.744   19.126 1.00 13.82 ?  274  ILE A HD13 1 
ATOM   4084  N N    . ILE A 1 309 ? -12.184 -0.331  24.386 1.00 7.31  ?  275  ILE A N    1 
ATOM   4085  C CA   . ILE A 1 309 ? -12.409 0.373   25.645 1.00 7.77  ?  275  ILE A CA   1 
ATOM   4086  C C    . ILE A 1 309 ? -11.089 0.973   26.077 1.00 8.04  ?  275  ILE A C    1 
ATOM   4087  O O    . ILE A 1 309 ? -10.073 0.273   26.129 1.00 8.39  ?  275  ILE A O    1 
ATOM   4088  C CB   . ILE A 1 309 ? -12.931 -0.571  26.747 1.00 8.93  ?  275  ILE A CB   1 
ATOM   4089  C CG1  . ILE A 1 309 ? -14.353 -1.030  26.416 1.00 10.62 ?  275  ILE A CG1  1 
ATOM   4090  C CG2  . ILE A 1 309 ? -12.876 0.076   28.105 1.00 10.05 ?  275  ILE A CG2  1 
ATOM   4091  C CD1  . ILE A 1 309 ? -15.402 0.091   26.504 1.00 11.85 ?  275  ILE A CD1  1 
ATOM   4092  H H    . ILE A 1 309 ? -11.568 -0.929  24.433 1.00 8.77  ?  275  ILE A H    1 
ATOM   4093  H HA   . ILE A 1 309 ? -13.060 1.078   25.503 1.00 9.32  ?  275  ILE A HA   1 
ATOM   4094  H HB   . ILE A 1 309 ? -12.351 -1.347  26.774 1.00 10.72 ?  275  ILE A HB   1 
ATOM   4095  H HG12 . ILE A 1 309 ? -14.366 -1.377  25.510 1.00 12.75 ?  275  ILE A HG12 1 
ATOM   4096  H HG13 . ILE A 1 309 ? -14.609 -1.726  27.041 1.00 12.75 ?  275  ILE A HG13 1 
ATOM   4097  H HG21 . ILE A 1 309 ? -13.417 -0.439  28.723 1.00 12.07 ?  275  ILE A HG21 1 
ATOM   4098  H HG22 . ILE A 1 309 ? -11.955 0.095   28.408 1.00 12.07 ?  275  ILE A HG22 1 
ATOM   4099  H HG23 . ILE A 1 309 ? -13.220 0.981   28.038 1.00 12.07 ?  275  ILE A HG23 1 
ATOM   4100  H HD11 . ILE A 1 309 ? -16.275 -0.277  26.296 1.00 14.22 ?  275  ILE A HD11 1 
ATOM   4101  H HD12 . ILE A 1 309 ? -15.401 0.454   27.403 1.00 14.22 ?  275  ILE A HD12 1 
ATOM   4102  H HD13 . ILE A 1 309 ? -15.176 0.786   25.866 1.00 14.22 ?  275  ILE A HD13 1 
ATOM   4103  N N    . THR A 1 310 ? -11.082 2.275   26.384 1.00 8.11  ?  276  THR A N    1 
ATOM   4104  C CA   . THR A 1 310 ? -9.910  2.911   26.993 1.00 8.19  ?  276  THR A CA   1 
ATOM   4105  C C    . THR A 1 310 ? -10.355 3.481   28.335 1.00 7.20  ?  276  THR A C    1 
ATOM   4106  O O    . THR A 1 310 ? -10.926 4.580   28.398 1.00 7.89  ?  276  THR A O    1 
ATOM   4107  C CB   . THR A 1 310 ? -9.232  3.937   26.080 1.00 7.73  ?  276  THR A CB   1 
ATOM   4108  O OG1  . THR A 1 310 ? -10.089 5.065   25.837 1.00 8.26  ?  276  THR A OG1  1 
ATOM   4109  C CG2  . THR A 1 310 ? -8.876  3.330   24.755 1.00 8.14  ?  276  THR A CG2  1 
ATOM   4110  H H    . THR A 1 310 ? -11.743 2.808   26.248 1.00 9.73  ?  276  THR A H    1 
ATOM   4111  H HA   . THR A 1 310 ? -9.232  2.238   27.159 1.00 9.83  ?  276  THR A HA   1 
ATOM   4112  H HB   . THR A 1 310 ? -8.424  4.235   26.526 1.00 9.27  ?  276  THR A HB   1 
ATOM   4113  H HG1  . THR A 1 310 ? -10.239 5.472   26.557 1.00 9.91  ?  276  THR A HG1  1 
ATOM   4114  H HG21 . THR A 1 310 ? -8.349  3.956   24.235 1.00 9.76  ?  276  THR A HG21 1 
ATOM   4115  H HG22 . THR A 1 310 ? -8.362  2.519   24.889 1.00 9.76  ?  276  THR A HG22 1 
ATOM   4116  H HG23 . THR A 1 310 ? -9.683  3.113   24.262 1.00 9.76  ?  276  THR A HG23 1 
ATOM   4117  N N    . MET A 1 311 ? -10.143 2.719   29.390 1.00 8.02  ?  277  MET A N    1 
ATOM   4118  C CA   . MET A 1 311 ? -10.512 3.113   30.733 1.00 9.03  ?  277  MET A CA   1 
ATOM   4119  C C    . MET A 1 311 ? -9.462  4.015   31.346 1.00 8.29  ?  277  MET A C    1 
ATOM   4120  O O    . MET A 1 311 ? -8.320  3.588   31.549 1.00 9.02  ?  277  MET A O    1 
ATOM   4121  C CB   . MET A 1 311 ? -10.608 1.932   31.702 1.00 8.80  ?  277  MET A CB   1 
ATOM   4122  C CG   . MET A 1 311 ? -11.568 2.180   32.853 1.00 11.09 ?  277  MET A CG   1 
ATOM   4123  S SD   . MET A 1 311 ? -11.687 0.811   34.036 1.00 10.50 ?  277  MET A SD   1 
ATOM   4124  C CE   . MET A 1 311 ? -13.190 0.039   33.260 1.00 12.99 ?  277  MET A CE   1 
ATOM   4125  H H    . MET A 1 311 ? -9.773  1.944   29.354 1.00 9.63  ?  277  MET A H    1 
ATOM   4126  H HA   . MET A 1 311 ? -11.374 3.544   30.623 1.00 10.84 ?  277  MET A HA   1 
ATOM   4127  H HB2  . MET A 1 311 ? -10.920 1.152   31.217 1.00 10.56 ?  277  MET A HB2  1 
ATOM   4128  H HB3  . MET A 1 311 ? -9.730  1.761   32.077 1.00 10.56 ?  277  MET A HB3  1 
ATOM   4129  H HG2  . MET A 1 311 ? -11.270 2.964   33.341 1.00 13.31 ?  277  MET A HG2  1 
ATOM   4130  H HG3  . MET A 1 311 ? -12.454 2.332   32.490 1.00 13.31 ?  277  MET A HG3  1 
ATOM   4131  H HE1  . MET A 1 311 ? -13.455 -0.733  33.784 1.00 15.59 ?  277  MET A HE1  1 
ATOM   4132  H HE2  . MET A 1 311 ? -13.909 0.691   33.246 1.00 15.59 ?  277  MET A HE2  1 
ATOM   4133  H HE3  . MET A 1 311 ? -12.974 -0.234  32.355 1.00 15.59 ?  277  MET A HE3  1 
ATOM   4134  N N    . THR A 1 312 ? -9.856  5.230   31.707 1.00 7.93  ?  278  THR A N    1 
ATOM   4135  C CA   . THR A 1 312 ? -8.986  6.125   32.456 1.00 7.89  ?  278  THR A CA   1 
ATOM   4136  C C    . THR A 1 312 ? -9.505  6.224   33.881 1.00 7.98  ?  278  THR A C    1 
ATOM   4137  O O    . THR A 1 312 ? -10.712 6.289   34.113 1.00 9.58  ?  278  THR A O    1 
ATOM   4138  C CB   . THR A 1 312 ? -8.859  7.509   31.806 1.00 7.68  ?  278  THR A CB   1 
ATOM   4139  O OG1  . THR A 1 312 ? -10.064 8.276   31.941 1.00 8.20  ?  278  THR A OG1  1 
ATOM   4140  C CG2  . THR A 1 312 ? -8.493  7.346   30.345 1.00 8.89  ?  278  THR A CG2  1 
ATOM   4141  H H    . THR A 1 312 ? -10.630 5.560   31.529 1.00 9.52  ?  278  THR A H    1 
ATOM   4142  H HA   . THR A 1 312 ? -8.085  5.766   32.477 1.00 9.46  ?  278  THR A HA   1 
ATOM   4143  H HB   . THR A 1 312 ? -8.161  8.010   32.256 1.00 9.21  ?  278  THR A HB   1 
ATOM   4144  H HG1  . THR A 1 312 ? -10.634 8.016   31.382 1.00 9.84  ?  278  THR A HG1  1 
ATOM   4145  H HG21 . THR A 1 312 ? -8.275  8.209   29.960 1.00 10.67 ?  278  THR A HG21 1 
ATOM   4146  H HG22 . THR A 1 312 ? -7.726  6.759   30.259 1.00 10.67 ?  278  THR A HG22 1 
ATOM   4147  H HG23 . THR A 1 312 ? -9.239  6.963   29.857 1.00 10.67 ?  278  THR A HG23 1 
ATOM   4148  N N    . LEU A 1 313 ? -8.577  6.188   34.831 1.00 9.40  ?  279  LEU A N    1 
ATOM   4149  C CA   . LEU A 1 313 ? -8.878  6.241   36.257 1.00 8.83  ?  279  LEU A CA   1 
ATOM   4150  C C    . LEU A 1 313 ? -7.819  7.125   36.893 1.00 8.92  ?  279  LEU A C    1 
ATOM   4151  O O    . LEU A 1 313 ? -6.626  6.935   36.658 1.00 10.08 ?  279  LEU A O    1 
ATOM   4152  C CB   . LEU A 1 313 ? -8.837  4.842   36.890 1.00 10.31 ?  279  LEU A CB   1 
ATOM   4153  C CG   . LEU A 1 313 ? -9.984  3.936   36.430 1.00 11.13 ?  279  LEU A CG   1 
ATOM   4154  C CD1  . LEU A 1 313 ? -9.710  2.464   36.790 1.00 12.64 ?  279  LEU A CD1  1 
ATOM   4155  C CD2  . LEU A 1 313 ? -11.298 4.353   37.025 1.00 16.51 ?  279  LEU A CD2  1 
ATOM   4156  H H    . LEU A 1 313 ? -7.735  6.131   34.669 1.00 11.28 ?  279  LEU A H    1 
ATOM   4157  H HA   . LEU A 1 313 ? -9.762  6.610   36.410 1.00 10.60 ?  279  LEU A HA   1 
ATOM   4158  H HB2  . LEU A 1 313 ? -8.002  4.413   36.648 1.00 12.38 ?  279  LEU A HB2  1 
ATOM   4159  H HB3  . LEU A 1 313 ? -8.897  4.934   37.854 1.00 12.38 ?  279  LEU A HB3  1 
ATOM   4160  H HG   . LEU A 1 313 ? -10.044 4.018   35.465 1.00 13.35 ?  279  LEU A HG   1 
ATOM   4161  H HD11 . LEU A 1 313 ? -10.396 1.908   36.389 1.00 15.16 ?  279  LEU A HD11 1 
ATOM   4162  H HD12 . LEU A 1 313 ? -8.838  2.212   36.447 1.00 15.16 ?  279  LEU A HD12 1 
ATOM   4163  H HD13 . LEU A 1 313 ? -9.727  2.367   37.755 1.00 15.16 ?  279  LEU A HD13 1 
ATOM   4164  H HD21 . LEU A 1 313 ? -11.993 3.757   36.705 1.00 19.81 ?  279  LEU A HD21 1 
ATOM   4165  H HD22 . LEU A 1 313 ? -11.237 4.302   37.992 1.00 19.81 ?  279  LEU A HD22 1 
ATOM   4166  H HD23 . LEU A 1 313 ? -11.492 5.264   36.754 1.00 19.81 ?  279  LEU A HD23 1 
ATOM   4167  N N    . GLY A 1 314 ? -8.256  8.092   37.693 1.00 9.41  ?  280  GLY A N    1 
ATOM   4168  C CA   . GLY A 1 314 ? -7.324  9.035   38.296 1.00 10.28 ?  280  GLY A CA   1 
ATOM   4169  C C    . GLY A 1 314 ? -6.662  8.505   39.554 1.00 13.33 ?  280  GLY A C    1 
ATOM   4170  O O    . GLY A 1 314 ? -7.302  7.892   40.413 1.00 13.45 ?  280  GLY A O    1 
ATOM   4171  H H    . GLY A 1 314 ? -9.081  8.223   37.900 1.00 11.30 ?  280  GLY A H    1 
ATOM   4172  H HA2  . GLY A 1 314 ? -6.628  9.247   37.656 1.00 12.34 ?  280  GLY A HA2  1 
ATOM   4173  H HA3  . GLY A 1 314 ? -7.800  9.848   38.527 1.00 12.34 ?  280  GLY A HA3  1 
ATOM   4174  N N    . LEU A 1 315 ? -5.353  8.727   39.630 1.00 11.54 ?  281  LEU A N    1 
ATOM   4175  C CA   . LEU A 1 315 ? -4.551  8.580   40.836 1.00 13.92 ?  281  LEU A CA   1 
ATOM   4176  C C    . LEU A 1 315 ? -4.250  9.913   41.522 1.00 18.35 ?  281  LEU A C    1 
ATOM   4177  O O    . LEU A 1 315 ? -3.556  9.915   42.554 1.00 17.70 ?  281  LEU A O    1 
ATOM   4178  C CB   . LEU A 1 315 ? -3.198  7.995   40.456 1.00 15.90 ?  281  LEU A CB   1 
ATOM   4179  C CG   . LEU A 1 315 ? -3.099  6.526   40.107 1.00 13.83 ?  281  LEU A CG   1 
ATOM   4180  C CD1  . LEU A 1 315 ? -1.703  6.198   39.626 1.00 22.56 ?  281  LEU A CD1  1 
ATOM   4181  C CD2  . LEU A 1 315 ? -3.410  5.705   41.326 1.00 17.06 ?  281  LEU A CD2  1 
ATOM   4182  H H    . LEU A 1 315 ? -4.881  8.979   38.957 1.00 13.85 ?  281  LEU A H    1 
ATOM   4183  H HA   . LEU A 1 315 ? -5.032  7.999   41.447 1.00 16.70 ?  281  LEU A HA   1 
ATOM   4184  H HB2  . LEU A 1 315 ? -2.879  8.482   39.680 1.00 19.08 ?  281  LEU A HB2  1 
ATOM   4185  H HB3  . LEU A 1 315 ? -2.599  8.138   41.206 1.00 19.08 ?  281  LEU A HB3  1 
ATOM   4186  H HG   . LEU A 1 315 ? -3.731  6.315   39.401 1.00 16.60 ?  281  LEU A HG   1 
ATOM   4187  H HD11 . LEU A 1 315 ? -1.675  5.270   39.345 1.00 27.07 ?  281  LEU A HD11 1 
ATOM   4188  H HD12 . LEU A 1 315 ? -1.482  6.776   38.879 1.00 27.07 ?  281  LEU A HD12 1 
ATOM   4189  H HD13 . LEU A 1 315 ? -1.077  6.342   40.353 1.00 27.07 ?  281  LEU A HD13 1 
ATOM   4190  H HD21 . LEU A 1 315 ? -3.268  4.768   41.121 1.00 20.47 ?  281  LEU A HD21 1 
ATOM   4191  H HD22 . LEU A 1 315 ? -2.822  5.978   42.048 1.00 20.47 ?  281  LEU A HD22 1 
ATOM   4192  H HD23 . LEU A 1 315 ? -4.335  5.853   41.579 1.00 20.47 ?  281  LEU A HD23 1 
ATOM   4193  N N    . GLY A 1 316 ? -4.713  11.040  40.973 1.00 18.75 ?  282  GLY A N    1 
ATOM   4194  C CA   . GLY A 1 316 ? -4.288  12.336  41.486 1.00 19.98 ?  282  GLY A CA   1 
ATOM   4195  C C    . GLY A 1 316 ? -4.532  12.512  42.972 1.00 26.18 ?  282  GLY A C    1 
ATOM   4196  O O    . GLY A 1 316 ? -3.701  13.090  43.682 1.00 25.03 ?  282  GLY A O    1 
ATOM   4197  H H    . GLY A 1 316 ? -5.265  11.077  40.314 1.00 22.50 ?  282  GLY A H    1 
ATOM   4198  H HA2  . GLY A 1 316 ? -3.338  12.445  41.323 1.00 23.98 ?  282  GLY A HA2  1 
ATOM   4199  H HA3  . GLY A 1 316 ? -4.771  13.036  41.018 1.00 23.98 ?  282  GLY A HA3  1 
ATOM   4200  N N    . GLU A 1 317 ? -5.667  12.015  43.466 1.00 23.99 ?  283  GLU A N    1 
ATOM   4201  C CA   . GLU A 1 317 ? -5.999  12.173  44.878 1.00 30.01 ?  283  GLU A CA   1 
ATOM   4202  C C    . GLU A 1 317 ? -5.104  11.318  45.765 1.00 33.05 ?  283  GLU A C    1 
ATOM   4203  O O    . GLU A 1 317 ? -4.767  11.727  46.882 1.00 33.74 ?  283  GLU A O    1 
ATOM   4204  C CB   . GLU A 1 317 ? -7.469  11.820  45.114 1.00 30.23 ?  283  GLU A CB   1 
ATOM   4205  H H    . GLU A 1 317 ? -6.255  11.587  43.008 1.00 28.79 ?  283  GLU A H    1 
ATOM   4206  H HA   . GLU A 1 317 ? -5.867  13.102  45.126 1.00 36.01 ?  283  GLU A HA   1 
ATOM   4207  H HB2  . GLU A 1 317 ? -7.697  11.034  44.592 1.00 36.28 ?  283  GLU A HB2  1 
ATOM   4208  H HB3  . GLU A 1 317 ? -7.604  11.642  46.058 1.00 36.28 ?  283  GLU A HB3  1 
ATOM   4209  N N    . ALA A 1 318 ? -4.708  10.139  45.288 1.00 23.69 ?  284  ALA A N    1 
ATOM   4210  C CA   . ALA A 1 318 ? -3.824  9.262   46.042 1.00 23.25 ?  284  ALA A CA   1 
ATOM   4211  C C    . ALA A 1 318 ? -2.379  9.743   46.023 1.00 30.88 ?  284  ALA A C    1 
ATOM   4212  O O    . ALA A 1 318 ? -1.596  9.357   46.900 1.00 30.81 ?  284  ALA A O    1 
ATOM   4213  C CB   . ALA A 1 318 ? -3.882  7.855   45.446 1.00 23.11 ?  284  ALA A CB   1 
ATOM   4214  H H    . ALA A 1 318 ? -4.941  9.823   44.523 1.00 28.42 ?  284  ALA A H    1 
ATOM   4215  H HA   . ALA A 1 318 ? -4.122  9.226   46.965 1.00 27.90 ?  284  ALA A HA   1 
ATOM   4216  H HB1  . ALA A 1 318 ? -3.278  7.278   45.939 1.00 27.73 ?  284  ALA A HB1  1 
ATOM   4217  H HB2  . ALA A 1 318 ? -4.789  7.520   45.515 1.00 27.73 ?  284  ALA A HB2  1 
ATOM   4218  H HB3  . ALA A 1 318 ? -3.614  7.896   44.515 1.00 27.73 ?  284  ALA A HB3  1 
ATOM   4219  N N    . ILE A 1 319 ? -2.018  10.564  45.043 1.00 19.80 ?  285  ILE A N    1 
ATOM   4220  C CA   . ILE A 1 319 ? -0.664  11.090  44.910 1.00 22.57 ?  285  ILE A CA   1 
ATOM   4221  C C    . ILE A 1 319 ? -0.506  12.417  45.636 1.00 25.60 ?  285  ILE A C    1 
ATOM   4222  O O    . ILE A 1 319 ? 0.566   12.709  46.168 1.00 30.85 ?  285  ILE A O    1 
ATOM   4223  C CB   . ILE A 1 319 ? -0.344  11.237  43.410 1.00 25.61 ?  285  ILE A CB   1 
ATOM   4224  C CG1  . ILE A 1 319 ? 0.048   9.886   42.809 1.00 22.66 ?  285  ILE A CG1  1 
ATOM   4225  C CG2  . ILE A 1 319 ? 0.772   12.250  43.202 1.00 31.11 ?  285  ILE A CG2  1 
ATOM   4226  C CD1  . ILE A 1 319 ? 0.034   9.876   41.293 1.00 25.98 ?  285  ILE A CD1  1 
ATOM   4227  H H    . ILE A 1 319 ? -2.551  10.838  44.426 1.00 23.76 ?  285  ILE A H    1 
ATOM   4228  H HA   . ILE A 1 319 ? -0.038  10.467  45.311 1.00 27.08 ?  285  ILE A HA   1 
ATOM   4229  H HB   . ILE A 1 319 ? -1.143  11.554  42.961 1.00 30.74 ?  285  ILE A HB   1 
ATOM   4230  H HG12 . ILE A 1 319 ? 0.945   9.662   43.100 1.00 27.19 ?  285  ILE A HG12 1 
ATOM   4231  H HG13 . ILE A 1 319 ? -0.579  9.213   43.117 1.00 27.19 ?  285  ILE A HG13 1 
ATOM   4232  H HG21 . ILE A 1 319 ? 1.055   12.222  42.275 1.00 37.34 ?  285  ILE A HG21 1 
ATOM   4233  H HG22 . ILE A 1 319 ? 0.440   13.135  43.420 1.00 37.34 ?  285  ILE A HG22 1 
ATOM   4234  H HG23 . ILE A 1 319 ? 1.516   12.023  43.782 1.00 37.34 ?  285  ILE A HG23 1 
ATOM   4235  H HD11 . ILE A 1 319 ? 0.269   8.988   40.981 1.00 31.18 ?  285  ILE A HD11 1 
ATOM   4236  H HD12 . ILE A 1 319 ? -0.855  10.111  40.984 1.00 31.18 ?  285  ILE A HD12 1 
ATOM   4237  H HD13 . ILE A 1 319 ? 0.679   10.523  40.967 1.00 31.18 ?  285  ILE A HD13 1 
ATOM   4238  N N    . ASP A 1 320 ? -1.536  13.260  45.641 1.00 22.47 ?  286  ASP A N    1 
ATOM   4239  C CA   . ASP A 1 320 ? -1.390  14.596  46.206 1.00 23.90 ?  286  ASP A CA   1 
ATOM   4240  C C    . ASP A 1 320 ? -0.883  14.521  47.641 1.00 32.49 ?  286  ASP A C    1 
ATOM   4241  O O    . ASP A 1 320 ? -1.318  13.679  48.433 1.00 25.51 ?  286  ASP A O    1 
ATOM   4242  C CB   . ASP A 1 320 ? -2.718  15.347  46.170 1.00 31.50 ?  286  ASP A CB   1 
ATOM   4243  C CG   . ASP A 1 320 ? -2.550  16.819  46.488 1.00 45.51 ?  286  ASP A CG   1 
ATOM   4244  O OD1  . ASP A 1 320 ? -2.188  17.598  45.577 1.00 45.54 ?  286  ASP A OD1  1 
ATOM   4245  O OD2  . ASP A 1 320 ? -2.744  17.188  47.667 1.00 43.12 ?  286  ASP A OD2  1 
ATOM   4246  H H    . ASP A 1 320 ? -2.318  13.084  45.328 1.00 26.96 ?  286  ASP A H    1 
ATOM   4247  H HA   . ASP A 1 320 ? -0.749  15.090  45.671 1.00 28.68 ?  286  ASP A HA   1 
ATOM   4248  H HB2  . ASP A 1 320 ? -3.104  15.271  45.284 1.00 37.80 ?  286  ASP A HB2  1 
ATOM   4249  H HB3  . ASP A 1 320 ? -3.319  14.962  46.828 1.00 37.80 ?  286  ASP A HB3  1 
ATOM   4250  N N    . ASN A 1 321 ? 0.038   15.429  47.974 1.00 30.08 ?  287  ASN A N    1 
ATOM   4251  C CA   . ASN A 1 321 ? 0.728   15.427  49.259 1.00 29.67 ?  287  ASN A CA   1 
ATOM   4252  C C    . ASN A 1 321 ? 0.775   16.825  49.869 1.00 35.01 ?  287  ASN A C    1 
ATOM   4253  O O    . ASN A 1 321 ? 1.659   17.108  50.685 1.00 30.57 ?  287  ASN A O    1 
ATOM   4254  C CB   . ASN A 1 321 ? 2.145   14.866  49.095 1.00 30.83 ?  287  ASN A CB   1 
ATOM   4255  C CG   . ASN A 1 321 ? 2.936   15.588  48.008 1.00 33.94 ?  287  ASN A CG   1 
ATOM   4256  O OD1  . ASN A 1 321 ? 2.601   16.711  47.640 1.00 28.82 ?  287  ASN A OD1  1 
ATOM   4257  N ND2  . ASN A 1 321 ? 3.977   14.941  47.480 1.00 30.37 ?  287  ASN A ND2  1 
ATOM   4258  H H    . ASN A 1 321 ? 0.286   16.070  47.457 1.00 36.09 ?  287  ASN A H    1 
ATOM   4259  H HA   . ASN A 1 321 ? 0.248   14.856  49.880 1.00 35.60 ?  287  ASN A HA   1 
ATOM   4260  H HB2  . ASN A 1 321 ? 2.625   14.965  49.932 1.00 36.99 ?  287  ASN A HB2  1 
ATOM   4261  H HB3  . ASN A 1 321 ? 2.089   13.928  48.854 1.00 36.99 ?  287  ASN A HB3  1 
ATOM   4262  H HD21 . ASN A 1 321 ? 4.448   15.314  46.864 1.00 36.45 ?  287  ASN A HD21 1 
ATOM   4263  H HD22 . ASN A 1 321 ? 4.176   14.151  47.755 1.00 36.45 ?  287  ASN A HD22 1 
ATOM   4264  N N    . ASN A 1 322 ? -0.153  17.705  49.487 1.00 23.29 ?  288  ASN A N    1 
ATOM   4265  C CA   . ASN A 1 322 ? -0.233  19.060  50.035 1.00 30.62 ?  288  ASN A CA   1 
ATOM   4266  C C    . ASN A 1 322 ? 1.059   19.842  49.795 1.00 27.14 ?  288  ASN A C    1 
ATOM   4267  O O    . ASN A 1 322 ? 1.562   20.533  50.688 1.00 22.60 ?  288  ASN A O    1 
ATOM   4268  C CB   . ASN A 1 322 ? -0.591  19.052  51.526 1.00 33.90 ?  288  ASN A CB   1 
ATOM   4269  C CG   . ASN A 1 322 ? -2.042  18.697  51.780 1.00 39.97 ?  288  ASN A CG   1 
ATOM   4270  O OD1  . ASN A 1 322 ? -2.924  19.024  50.985 1.00 42.61 ?  288  ASN A OD1  1 
ATOM   4271  N ND2  . ASN A 1 322 ? -2.300  18.038  52.909 1.00 37.05 ?  288  ASN A ND2  1 
ATOM   4272  H H    . ASN A 1 322 ? -0.760  17.537  48.901 1.00 27.95 ?  288  ASN A H    1 
ATOM   4273  H HA   . ASN A 1 322 ? -0.944  19.523  49.565 1.00 36.74 ?  288  ASN A HA   1 
ATOM   4274  H HB2  . ASN A 1 322 ? -0.038  18.398  51.980 1.00 40.69 ?  288  ASN A HB2  1 
ATOM   4275  H HB3  . ASN A 1 322 ? -0.431  19.935  51.894 1.00 40.69 ?  288  ASN A HB3  1 
ATOM   4276  H HD21 . ASN A 1 322 ? -1.659  17.839  53.446 1.00 44.46 ?  288  ASN A HD21 1 
ATOM   4277  H HD22 . ASN A 1 322 ? -3.107  17.813  53.100 1.00 44.46 ?  288  ASN A HD22 1 
ATOM   4278  N N    . THR A 1 323 ? 1.605   19.726  48.583 1.00 17.00 ?  289  THR A N    1 
ATOM   4279  C CA   . THR A 1 323 ? 2.760   20.514  48.171 1.00 14.69 ?  289  THR A CA   1 
ATOM   4280  C C    . THR A 1 323 ? 2.615   20.869  46.700 1.00 16.00 ?  289  THR A C    1 
ATOM   4281  O O    . THR A 1 323 ? 1.838   20.250  45.974 1.00 19.15 ?  289  THR A O    1 
ATOM   4282  C CB   . THR A 1 323 ? 4.093   19.768  48.376 1.00 15.18 ?  289  THR A CB   1 
ATOM   4283  O OG1  . THR A 1 323 ? 4.172   18.645  47.476 1.00 17.70 ?  289  THR A OG1  1 
ATOM   4284  C CG2  . THR A 1 323 ? 4.242   19.263  49.800 1.00 19.15 ?  289  THR A CG2  1 
ATOM   4285  H H    . THR A 1 323 ? 1.318   19.190  47.975 1.00 20.40 ?  289  THR A H    1 
ATOM   4286  H HA   . THR A 1 323 ? 2.781   21.325  48.703 1.00 17.62 ?  289  THR A HA   1 
ATOM   4287  H HB   . THR A 1 323 ? 4.817   20.387  48.198 1.00 18.21 ?  289  THR A HB   1 
ATOM   4288  H HG1  . THR A 1 323 ? 3.542   18.111  47.626 1.00 21.24 ?  289  THR A HG1  1 
ATOM   4289  H HG21 . THR A 1 323 ? 5.128   18.891  49.930 1.00 22.98 ?  289  THR A HG21 1 
ATOM   4290  H HG22 . THR A 1 323 ? 4.112   19.993  50.426 1.00 22.98 ?  289  THR A HG22 1 
ATOM   4291  H HG23 . THR A 1 323 ? 3.582   18.574  49.979 1.00 22.98 ?  289  THR A HG23 1 
ATOM   4292  N N    . GLY A 1 324 ? 3.355   21.887  46.264 1.00 12.99 ?  290  GLY A N    1 
ATOM   4293  C CA   . GLY A 1 324 ? 3.430   22.252  44.868 1.00 12.08 ?  290  GLY A CA   1 
ATOM   4294  C C    . GLY A 1 324 ? 2.762   23.557  44.491 1.00 13.08 ?  290  GLY A C    1 
ATOM   4295  O O    . GLY A 1 324 ? 2.914   23.987  43.339 1.00 15.50 ?  290  GLY A O    1 
ATOM   4296  H H    . GLY A 1 324 ? 3.830   22.388  46.777 1.00 15.59 ?  290  GLY A H    1 
ATOM   4297  H HA2  . GLY A 1 324 ? 4.364   22.320  44.619 1.00 14.50 ?  290  GLY A HA2  1 
ATOM   4298  H HA3  . GLY A 1 324 ? 3.013   21.550  44.345 1.00 14.50 ?  290  GLY A HA3  1 
ATOM   4299  N N    . ILE A 1 325 ? 2.030   24.194  45.400 1.00 12.26 ?  291  ILE A N    1 
ATOM   4300  C CA   . ILE A 1 325 ? 1.338   25.448  45.088 1.00 11.69 ?  291  ILE A CA   1 
ATOM   4301  C C    . ILE A 1 325 ? 2.252   26.646  45.323 1.00 10.42 ?  291  ILE A C    1 
ATOM   4302  O O    . ILE A 1 325 ? 2.470   27.467  44.420 1.00 11.25 ?  291  ILE A O    1 
ATOM   4303  C CB   . ILE A 1 325 ? 0.031   25.558  45.890 1.00 11.17 ?  291  ILE A CB   1 
ATOM   4304  C CG1  . ILE A 1 325 ? -0.914  24.402  45.540 1.00 13.59 ?  291  ILE A CG1  1 
ATOM   4305  C CG2  . ILE A 1 325 ? -0.637  26.900  45.630 1.00 11.14 ?  291  ILE A CG2  1 
ATOM   4306  C CD1  . ILE A 1 325 ? -2.213  24.400  46.339 1.00 21.80 ?  291  ILE A CD1  1 
ATOM   4307  H H    . ILE A 1 325 ? 1.915   23.922  46.207 1.00 14.71 ?  291  ILE A H    1 
ATOM   4308  H HA   . ILE A 1 325 ? 1.122   25.454  44.142 1.00 14.03 ?  291  ILE A HA   1 
ATOM   4309  H HB   . ILE A 1 325 ? 0.244   25.498  46.834 1.00 13.40 ?  291  ILE A HB   1 
ATOM   4310  H HG12 . ILE A 1 325 ? -1.145  24.463  44.600 1.00 16.30 ?  291  ILE A HG12 1 
ATOM   4311  H HG13 . ILE A 1 325 ? -0.458  23.564  45.715 1.00 16.30 ?  291  ILE A HG13 1 
ATOM   4312  H HG21 . ILE A 1 325 ? -1.509  26.907  46.056 1.00 13.37 ?  291  ILE A HG21 1 
ATOM   4313  H HG22 . ILE A 1 325 ? -0.083  27.606  45.999 1.00 13.37 ?  291  ILE A HG22 1 
ATOM   4314  H HG23 . ILE A 1 325 ? -0.736  27.024  44.673 1.00 13.37 ?  291  ILE A HG23 1 
ATOM   4315  H HD11 . ILE A 1 325 ? -2.954  24.574  45.738 1.00 26.16 ?  291  ILE A HD11 1 
ATOM   4316  H HD12 . ILE A 1 325 ? -2.324  23.533  46.759 1.00 26.16 ?  291  ILE A HD12 1 
ATOM   4317  H HD13 . ILE A 1 325 ? -2.168  25.092  47.017 1.00 26.16 ?  291  ILE A HD13 1 
ATOM   4318  N N    . ASP A 1 326 ? 2.785   26.756  46.539 1.00 10.88 ?  292  ASP A N    1 
ATOM   4319  C CA   . ASP A 1 326 ? 3.722   27.811  46.902 1.00 9.17  ?  292  ASP A CA   1 
ATOM   4320  C C    . ASP A 1 326 ? 5.070   27.251  47.329 1.00 12.20 ?  292  ASP A C    1 
ATOM   4321  O O    . ASP A 1 326 ? 5.897   27.989  47.867 1.00 12.24 ?  292  ASP A O    1 
ATOM   4322  C CB   . ASP A 1 326 ? 3.144   28.678  48.023 1.00 10.74 ?  292  ASP A CB   1 
ATOM   4323  C CG   . ASP A 1 326 ? 1.941   29.468  47.578 1.00 9.74  ?  292  ASP A CG   1 
ATOM   4324  O OD1  . ASP A 1 326 ? 2.119   30.304  46.678 1.00 10.57 ?  292  ASP A OD1  1 
ATOM   4325  O OD2  . ASP A 1 326 ? 0.853   29.244  48.140 1.00 10.16 ?  292  ASP A OD2  1 
ATOM   4326  H H    . ASP A 1 326 ? 2.614   26.216  47.186 1.00 13.05 ?  292  ASP A H    1 
ATOM   4327  H HA   . ASP A 1 326 ? 3.861   28.381  46.129 1.00 11.00 ?  292  ASP A HA   1 
ATOM   4328  H HB2  . ASP A 1 326 ? 2.874   28.106  48.758 1.00 12.89 ?  292  ASP A HB2  1 
ATOM   4329  H HB3  . ASP A 1 326 ? 3.823   29.304  48.321 1.00 12.89 ?  292  ASP A HB3  1 
ATOM   4330  N N    . ASP A 1 327 ? 5.309   25.964  47.102 1.00 10.74 ?  293  ASP A N    1 
ATOM   4331  C CA   . ASP A 1 327 ? 6.555   25.288  47.443 1.00 10.97 ?  293  ASP A CA   1 
ATOM   4332  C C    . ASP A 1 327 ? 6.815   24.241  46.371 1.00 11.62 ?  293  ASP A C    1 
ATOM   4333  O O    . ASP A 1 327 ? 5.995   24.011  45.481 1.00 11.75 ?  293  ASP A O    1 
ATOM   4334  C CB   . ASP A 1 327 ? 6.554   24.726  48.877 1.00 12.04 ?  293  ASP A CB   1 
ATOM   4335  C CG   . ASP A 1 327 ? 5.335   23.883  49.213 1.00 12.45 ?  293  ASP A CG   1 
ATOM   4336  O OD1  . ASP A 1 327 ? 4.717   23.321  48.303 1.00 12.54 ?  293  ASP A OD1  1 
ATOM   4337  O OD2  . ASP A 1 327 ? 4.983   23.758  50.412 1.00 13.13 ?  293  ASP A OD2  1 
ATOM   4338  H H    . ASP A 1 327 ? 4.739   25.436  46.733 1.00 12.88 ?  293  ASP A H    1 
ATOM   4339  H HA   . ASP A 1 327 ? 7.294   25.915  47.423 1.00 13.17 ?  293  ASP A HA   1 
ATOM   4340  H HB2  . ASP A 1 327 ? 7.339   24.168  48.993 1.00 14.45 ?  293  ASP A HB2  1 
ATOM   4341  H HB3  . ASP A 1 327 ? 6.579   25.469  49.501 1.00 14.45 ?  293  ASP A HB3  1 
ATOM   4342  N N    . GLN A 1 328 ? 7.998   23.645  46.421 1.00 11.73 ?  294  GLN A N    1 
ATOM   4343  C CA   . GLN A 1 328 ? 8.292   22.549  45.503 1.00 12.57 ?  294  GLN A CA   1 
ATOM   4344  C C    . GLN A 1 328 ? 7.318   21.398  45.731 1.00 11.27 ?  294  GLN A C    1 
ATOM   4345  O O    . GLN A 1 328 ? 6.996   21.042  46.869 1.00 12.64 ?  294  GLN A O    1 
ATOM   4346  C CB   . GLN A 1 328 ? 9.726   22.077  45.740 1.00 15.37 ?  294  GLN A CB   1 
ATOM   4347  C CG   . GLN A 1 328 ? 10.087  20.730  45.122 1.00 21.29 ?  294  GLN A CG   1 
ATOM   4348  C CD   . GLN A 1 328 ? 11.564  20.413  45.279 1.00 21.30 ?  294  GLN A CD   1 
ATOM   4349  O OE1  . GLN A 1 328 ? 12.231  20.950  46.164 1.00 24.33 ?  294  GLN A OE1  1 
ATOM   4350  N NE2  . GLN A 1 328 ? 12.074  19.529  44.431 1.00 28.54 ?  294  GLN A NE2  1 
ATOM   4351  H H    . GLN A 1 328 ? 8.633   23.848  46.964 1.00 14.07 ?  294  GLN A H    1 
ATOM   4352  H HA   . GLN A 1 328 ? 8.205   22.843  44.583 1.00 15.08 ?  294  GLN A HA   1 
ATOM   4353  H HB2  . GLN A 1 328 ? 10.330  22.737  45.366 1.00 18.44 ?  294  GLN A HB2  1 
ATOM   4354  H HB3  . GLN A 1 328 ? 9.868   22.002  46.697 1.00 18.44 ?  294  GLN A HB3  1 
ATOM   4355  H HG2  . GLN A 1 328 ? 9.578   20.030  45.561 1.00 25.54 ?  294  GLN A HG2  1 
ATOM   4356  H HG3  . GLN A 1 328 ? 9.879   20.747  44.175 1.00 25.54 ?  294  GLN A HG3  1 
ATOM   4357  H HE21 . GLN A 1 328 ? 11.573  19.169  43.832 1.00 34.25 ?  294  GLN A HE21 1 
ATOM   4358  H HE22 . GLN A 1 328 ? 12.906  19.317  44.480 1.00 34.25 ?  294  GLN A HE22 1 
ATOM   4359  N N    . ARG A 1 329 ? 6.815   20.840  44.631 1.00 13.22 ?  295  ARG A N    1 
ATOM   4360  C CA   . ARG A 1 329 ? 6.060   19.595  44.709 1.00 13.30 ?  295  ARG A CA   1 
ATOM   4361  C C    . ARG A 1 329 ? 6.976   18.461  45.154 1.00 13.49 ?  295  ARG A C    1 
ATOM   4362  O O    . ARG A 1 329 ? 7.966   18.149  44.482 1.00 16.98 ?  295  ARG A O    1 
ATOM   4363  C CB   . ARG A 1 329 ? 5.425   19.268  43.360 1.00 15.27 ?  295  ARG A CB   1 
ATOM   4364  C CG   . ARG A 1 329 ? 4.313   18.248  43.468 1.00 15.35 ?  295  ARG A CG   1 
ATOM   4365  C CD   . ARG A 1 329 ? 3.904   17.779  42.088 1.00 22.82 ?  295  ARG A CD   1 
ATOM   4366  N NE   . ARG A 1 329 ? 2.936   16.698  42.170 1.00 22.05 ?  295  ARG A NE   1 
ATOM   4367  C CZ   . ARG A 1 329 ? 2.256   16.235  41.132 1.00 26.07 ?  295  ARG A CZ   1 
ATOM   4368  N NH1  . ARG A 1 329 ? 2.472   16.696  39.909 1.00 26.71 ?  295  ARG A NH1  1 
ATOM   4369  N NH2  . ARG A 1 329 ? 1.348   15.283  41.325 1.00 19.84 ?  295  ARG A NH2  1 
ATOM   4370  H H    . ARG A 1 329 ? 6.896   21.161  43.837 1.00 15.87 ?  295  ARG A H    1 
ATOM   4371  H HA   . ARG A 1 329 ? 5.349   19.695  45.361 1.00 15.96 ?  295  ARG A HA   1 
ATOM   4372  H HB2  . ARG A 1 329 ? 5.052   20.079  42.982 1.00 18.32 ?  295  ARG A HB2  1 
ATOM   4373  H HB3  . ARG A 1 329 ? 6.105   18.909  42.769 1.00 18.32 ?  295  ARG A HB3  1 
ATOM   4374  H HG2  . ARG A 1 329 ? 4.621   17.483  43.978 1.00 18.42 ?  295  ARG A HG2  1 
ATOM   4375  H HG3  . ARG A 1 329 ? 3.544   18.649  43.901 1.00 18.42 ?  295  ARG A HG3  1 
ATOM   4376  H HD2  . ARG A 1 329 ? 3.500   18.516  41.603 1.00 27.38 ?  295  ARG A HD2  1 
ATOM   4377  H HD3  . ARG A 1 329 ? 4.685   17.457  41.611 1.00 27.38 ?  295  ARG A HD3  1 
ATOM   4378  H HE   . ARG A 1 329 ? 2.797   16.338  42.939 1.00 26.46 ?  295  ARG A HE   1 
ATOM   4379  H HH11 . ARG A 1 329 ? 3.063   17.307  39.777 1.00 32.05 ?  295  ARG A HH11 1 
ATOM   4380  H HH12 . ARG A 1 329 ? 2.022   16.384  39.246 1.00 32.05 ?  295  ARG A HH12 1 
ATOM   4381  H HH21 . ARG A 1 329 ? 1.209   14.976  42.117 1.00 23.81 ?  295  ARG A HH21 1 
ATOM   4382  H HH22 . ARG A 1 329 ? 0.900   14.974  40.659 1.00 23.81 ?  295  ARG A HH22 1 
ATOM   4383  N N    . GLU A 1 330 ? 6.653   17.870  46.293 1.00 16.48 ?  296  GLU A N    1 
ATOM   4384  C CA   . GLU A 1 330 ? 7.503   16.827  46.848 1.00 19.77 ?  296  GLU A CA   1 
ATOM   4385  C C    . GLU A 1 330 ? 7.459   15.603  45.947 1.00 24.62 ?  296  GLU A C    1 
ATOM   4386  O O    . GLU A 1 330 ? 6.401   15.233  45.434 1.00 19.55 ?  296  GLU A O    1 
ATOM   4387  C CB   . GLU A 1 330 ? 7.034   16.477  48.252 1.00 21.80 ?  296  GLU A CB   1 
ATOM   4388  H H    . GLU A 1 330 ? 5.955   18.052  46.761 1.00 19.77 ?  296  GLU A H    1 
ATOM   4389  H HA   . GLU A 1 330 ? 8.422   17.129  46.907 1.00 23.72 ?  296  GLU A HA   1 
ATOM   4390  N N    . ASP A 1 331 ? 8.628   15.007  45.719 1.00 24.75 ?  297  ASP A N    1 
ATOM   4391  C CA   . ASP A 1 331 ? 8.711   13.833  44.867 1.00 27.39 ?  297  ASP A CA   1 
ATOM   4392  C C    . ASP A 1 331 ? 7.878   12.709  45.463 1.00 29.23 ?  297  ASP A C    1 
ATOM   4393  O O    . ASP A 1 331 ? 7.898   12.462  46.672 1.00 24.45 ?  297  ASP A O    1 
ATOM   4394  C CB   . ASP A 1 331 ? 10.168  13.387  44.725 1.00 36.84 ?  297  ASP A CB   1 
ATOM   4395  H H    . ASP A 1 331 ? 9.381   15.264  46.046 1.00 29.69 ?  297  ASP A H    1 
ATOM   4396  H HA   . ASP A 1 331 ? 8.373   14.042  43.982 1.00 32.87 ?  297  ASP A HA   1 
ATOM   4397  H HB2  . ASP A 1 331 ? 10.611  13.465  45.583 1.00 44.20 ?  297  ASP A HB2  1 
ATOM   4398  H HB3  . ASP A 1 331 ? 10.191  12.467  44.417 1.00 44.20 ?  297  ASP A HB3  1 
ATOM   4399  N N    . VAL A 1 332 ? 7.133   12.038  44.608 1.00 27.31 ?  298  VAL A N    1 
ATOM   4400  C CA   . VAL A 1 332 ? 6.251   10.958  45.022 1.00 30.92 ?  298  VAL A CA   1 
ATOM   4401  C C    . VAL A 1 332 ? 7.045   9.658   45.050 1.00 25.69 ?  298  VAL A C    1 
ATOM   4402  O O    . VAL A 1 332 ? 7.804   9.367   44.118 1.00 23.94 ?  298  VAL A O    1 
ATOM   4403  C CB   . VAL A 1 332 ? 5.056   10.848  44.061 1.00 33.07 ?  298  VAL A CB   1 
ATOM   4404  C CG1  . VAL A 1 332 ? 4.040   9.864   44.602 1.00 36.82 ?  298  VAL A CG1  1 
ATOM   4405  C CG2  . VAL A 1 332 ? 4.428   12.230  43.831 1.00 37.04 ?  298  VAL A CG2  1 
ATOM   4406  H H    . VAL A 1 332 ? 7.117   12.191  43.762 1.00 32.77 ?  298  VAL A H    1 
ATOM   4407  H HA   . VAL A 1 332 ? 5.922   11.131  45.918 1.00 37.11 ?  298  VAL A HA   1 
ATOM   4408  H HB   . VAL A 1 332 ? 5.362   10.517  43.202 1.00 39.68 ?  298  VAL A HB   1 
ATOM   4409  H HG11 . VAL A 1 332 ? 3.274   9.842   44.007 1.00 44.18 ?  298  VAL A HG11 1 
ATOM   4410  H HG12 . VAL A 1 332 ? 4.447   8.985   44.650 1.00 44.18 ?  298  VAL A HG12 1 
ATOM   4411  H HG13 . VAL A 1 332 ? 3.764   10.149  45.487 1.00 44.18 ?  298  VAL A HG13 1 
ATOM   4412  H HG21 . VAL A 1 332 ? 3.656   12.133  43.251 1.00 44.45 ?  298  VAL A HG21 1 
ATOM   4413  H HG22 . VAL A 1 332 ? 4.156   12.600  44.685 1.00 44.45 ?  298  VAL A HG22 1 
ATOM   4414  H HG23 . VAL A 1 332 ? 5.084   12.810  43.414 1.00 44.45 ?  298  VAL A HG23 1 
ATOM   4415  N N    . ASP A 1 333 ? 6.882   8.889   46.127 1.00 24.29 ?  299  ASP A N    1 
ATOM   4416  C CA   . ASP A 1 333 ? 7.427   7.535   46.196 1.00 20.67 ?  299  ASP A CA   1 
ATOM   4417  C C    . ASP A 1 333 ? 6.504   6.603   45.424 1.00 17.68 ?  299  ASP A C    1 
ATOM   4418  O O    . ASP A 1 333 ? 5.478   6.152   45.942 1.00 19.60 ?  299  ASP A O    1 
ATOM   4419  C CB   . ASP A 1 333 ? 7.560   7.069   47.638 1.00 26.10 ?  299  ASP A CB   1 
ATOM   4420  C CG   . ASP A 1 333 ? 8.184   5.695   47.743 1.00 25.68 ?  299  ASP A CG   1 
ATOM   4421  O OD1  . ASP A 1 333 ? 8.571   5.129   46.694 1.00 22.50 ?  299  ASP A OD1  1 
ATOM   4422  O OD2  . ASP A 1 333 ? 8.288   5.184   48.880 1.00 37.38 ?  299  ASP A OD2  1 
ATOM   4423  H H    . ASP A 1 333 ? 6.458   9.132   46.834 1.00 29.15 ?  299  ASP A H    1 
ATOM   4424  H HA   . ASP A 1 333 ? 8.306   7.534   45.784 1.00 24.81 ?  299  ASP A HA   1 
ATOM   4425  H HB2  . ASP A 1 333 ? 8.121   7.693   48.124 1.00 31.32 ?  299  ASP A HB2  1 
ATOM   4426  H HB3  . ASP A 1 333 ? 6.679   7.031   48.042 1.00 31.32 ?  299  ASP A HB3  1 
ATOM   4427  N N    . LEU A 1 334 ? 6.872   6.304   44.179 1.00 17.47 ?  300  LEU A N    1 
ATOM   4428  C CA   . LEU A 1 334 ? 6.009   5.457   43.365 1.00 19.72 ?  300  LEU A CA   1 
ATOM   4429  C C    . LEU A 1 334 ? 6.025   3.999   43.796 1.00 21.92 ?  300  LEU A C    1 
ATOM   4430  O O    . LEU A 1 334 ? 5.188   3.226   43.308 1.00 20.52 ?  300  LEU A O    1 
ATOM   4431  C CB   . LEU A 1 334 ? 6.346   5.596   41.885 1.00 19.41 ?  300  LEU A CB   1 
ATOM   4432  C CG   . LEU A 1 334 ? 6.218   7.039   41.381 1.00 19.30 ?  300  LEU A CG   1 
ATOM   4433  C CD1  . LEU A 1 334 ? 7.073   7.270   40.145 1.00 24.27 ?  300  LEU A CD1  1 
ATOM   4434  C CD2  . LEU A 1 334 ? 4.758   7.383   41.133 1.00 23.87 ?  300  LEU A CD2  1 
ATOM   4435  H H    . LEU A 1 334 ? 7.594   6.571   43.796 1.00 20.97 ?  300  LEU A H    1 
ATOM   4436  H HA   . LEU A 1 334 ? 5.096   5.771   43.466 1.00 23.66 ?  300  LEU A HA   1 
ATOM   4437  H HB2  . LEU A 1 334 ? 7.261   5.307   41.741 1.00 23.29 ?  300  LEU A HB2  1 
ATOM   4438  H HB3  . LEU A 1 334 ? 5.738   5.042   41.370 1.00 23.29 ?  300  LEU A HB3  1 
ATOM   4439  H HG   . LEU A 1 334 ? 6.550   7.645   42.062 1.00 23.15 ?  300  LEU A HG   1 
ATOM   4440  H HD11 . LEU A 1 334 ? 7.005   8.201   39.883 1.00 29.12 ?  300  LEU A HD11 1 
ATOM   4441  H HD12 . LEU A 1 334 ? 7.995   7.051   40.353 1.00 29.12 ?  300  LEU A HD12 1 
ATOM   4442  H HD13 . LEU A 1 334 ? 6.752   6.701   39.428 1.00 29.12 ?  300  LEU A HD13 1 
ATOM   4443  H HD21 . LEU A 1 334 ? 4.699   8.295   40.808 1.00 28.65 ?  300  LEU A HD21 1 
ATOM   4444  H HD22 . LEU A 1 334 ? 4.397   6.772   40.472 1.00 28.65 ?  300  LEU A HD22 1 
ATOM   4445  H HD23 . LEU A 1 334 ? 4.268   7.297   41.966 1.00 28.65 ?  300  LEU A HD23 1 
ATOM   4446  N N    . ASN A 1 335 ? 6.933   3.615   44.697 1.00 19.85 ?  301  ASN A N    1 
ATOM   4447  C CA   . ASN A 1 335 ? 6.908   2.296   45.321 1.00 19.88 ?  301  ASN A CA   1 
ATOM   4448  C C    . ASN A 1 335 ? 6.154   2.275   46.639 1.00 20.03 ?  301  ASN A C    1 
ATOM   4449  O O    . ASN A 1 335 ? 6.118   1.229   47.295 1.00 23.18 ?  301  ASN A O    1 
ATOM   4450  C CB   . ASN A 1 335 ? 8.328   1.753   45.542 1.00 22.98 ?  301  ASN A CB   1 
ATOM   4451  C CG   . ASN A 1 335 ? 9.124   1.693   44.270 1.00 30.05 ?  301  ASN A CG   1 
ATOM   4452  O OD1  . ASN A 1 335 ? 8.731   1.017   43.319 1.00 36.61 ?  301  ASN A OD1  1 
ATOM   4453  N ND2  . ASN A 1 335 ? 10.245  2.403   44.232 1.00 40.32 ?  301  ASN A ND2  1 
ATOM   4454  H H    . ASN A 1 335 ? 7.582   4.111   44.966 1.00 23.82 ?  301  ASN A H    1 
ATOM   4455  H HA   . ASN A 1 335 ? 6.464   1.692   44.706 1.00 23.86 ?  301  ASN A HA   1 
ATOM   4456  H HB2  . ASN A 1 335 ? 8.796   2.333   46.163 1.00 27.58 ?  301  ASN A HB2  1 
ATOM   4457  H HB3  . ASN A 1 335 ? 8.271   0.856   45.905 1.00 27.58 ?  301  ASN A HB3  1 
ATOM   4458  H HD21 . ASN A 1 335 ? 10.482  2.868   44.916 1.00 48.38 ?  301  ASN A HD21 1 
ATOM   4459  H HD22 . ASN A 1 335 ? 10.733  2.399   43.525 1.00 48.38 ?  301  ASN A HD22 1 
ATOM   4460  N N    . ASP A 1 336 ? 5.553   3.392   47.045 1.00 18.72 ?  302  ASP A N    1 
ATOM   4461  C CA   . ASP A 1 336 ? 4.820   3.444   48.302 1.00 21.17 ?  302  ASP A CA   1 
ATOM   4462  C C    . ASP A 1 336 ? 3.766   2.341   48.371 1.00 25.78 ?  302  ASP A C    1 
ATOM   4463  O O    . ASP A 1 336 ? 3.039   2.088   47.407 1.00 19.98 ?  302  ASP A O    1 
ATOM   4464  C CB   . ASP A 1 336 ? 4.160   4.816   48.442 1.00 21.12 ?  302  ASP A CB   1 
ATOM   4465  C CG   . ASP A 1 336 ? 3.353   4.947   49.703 1.00 27.25 ?  302  ASP A CG   1 
ATOM   4466  O OD1  . ASP A 1 336 ? 3.973   5.133   50.773 1.00 29.42 ?  302  ASP A OD1  1 
ATOM   4467  O OD2  . ASP A 1 336 ? 2.109   4.909   49.630 1.00 24.68 ?  302  ASP A OD2  1 
ATOM   4468  H H    . ASP A 1 336 ? 5.557   4.133   46.609 1.00 22.46 ?  302  ASP A H    1 
ATOM   4469  H HA   . ASP A 1 336 ? 5.432   3.311   49.043 1.00 25.41 ?  302  ASP A HA   1 
ATOM   4470  H HB2  . ASP A 1 336 ? 4.849   5.499   48.455 1.00 25.34 ?  302  ASP A HB2  1 
ATOM   4471  H HB3  . ASP A 1 336 ? 3.565   4.959   47.689 1.00 25.34 ?  302  ASP A HB3  1 
ATOM   4472  N N    . GLU A 1 337 ? 3.676   1.694   49.535 1.00 20.11 ?  303  GLU A N    1 
ATOM   4473  C CA   . GLU A 1 337 ? 2.774   0.555   49.701 1.00 19.14 ?  303  GLU A CA   1 
ATOM   4474  C C    . GLU A 1 337 ? 1.317   0.964   49.528 1.00 21.32 ?  303  GLU A C    1 
ATOM   4475  O O    . GLU A 1 337 ? 0.536   0.265   48.870 1.00 19.56 ?  303  GLU A O    1 
ATOM   4476  C CB   . GLU A 1 337 ? 2.984   -0.064  51.087 1.00 27.69 ?  303  GLU A CB   1 
ATOM   4477  C CG   . GLU A 1 337 ? 2.123   -1.279  51.376 1.00 36.55 ?  303  GLU A CG   1 
ATOM   4478  C CD   . GLU A 1 337 ? 2.236   -1.736  52.819 1.00 46.86 ?  303  GLU A CD   1 
ATOM   4479  O OE1  . GLU A 1 337 ? 1.204   -1.747  53.525 1.00 47.66 ?  303  GLU A OE1  1 
ATOM   4480  O OE2  . GLU A 1 337 ? 3.360   -2.079  53.244 1.00 49.20 ?  303  GLU A OE2  1 
ATOM   4481  H H    . GLU A 1 337 ? 4.124   1.894   50.242 1.00 24.14 ?  303  GLU A H    1 
ATOM   4482  H HA   . GLU A 1 337 ? 2.982   -0.106  49.022 1.00 22.97 ?  303  GLU A HA   1 
ATOM   4483  H HB2  . GLU A 1 337 ? 3.912   -0.338  51.165 1.00 33.23 ?  303  GLU A HB2  1 
ATOM   4484  H HB3  . GLU A 1 337 ? 2.779   0.606   51.758 1.00 33.23 ?  303  GLU A HB3  1 
ATOM   4485  H HG2  . GLU A 1 337 ? 1.194   -1.059  51.201 1.00 43.86 ?  303  GLU A HG2  1 
ATOM   4486  H HG3  . GLU A 1 337 ? 2.404   -2.011  50.804 1.00 43.86 ?  303  GLU A HG3  1 
ATOM   4487  N N    . GLU A 1 338 ? 0.919   2.077   50.137 1.00 20.41 ?  304  GLU A N    1 
ATOM   4488  C CA   . GLU A 1 338 ? -0.471  2.504   50.029 1.00 20.67 ?  304  GLU A CA   1 
ATOM   4489  C C    . GLU A 1 338 ? -0.815  2.931   48.607 1.00 20.72 ?  304  GLU A C    1 
ATOM   4490  O O    . GLU A 1 338 ? -1.909  2.636   48.116 1.00 21.13 ?  304  GLU A O    1 
ATOM   4491  C CB   . GLU A 1 338 ? -0.766  3.627   51.024 1.00 30.39 ?  304  GLU A CB   1 
ATOM   4492  C CG   . GLU A 1 338 ? -0.863  3.158   52.472 1.00 42.78 ?  304  GLU A CG   1 
ATOM   4493  C CD   . GLU A 1 338 ? -1.986  2.157   52.693 1.00 43.82 ?  304  GLU A CD   1 
ATOM   4494  O OE1  . GLU A 1 338 ? -1.695  1.009   53.098 1.00 44.72 ?  304  GLU A OE1  1 
ATOM   4495  O OE2  . GLU A 1 338 ? -3.160  2.519   52.455 1.00 45.92 ?  304  GLU A OE2  1 
ATOM   4496  H H    . GLU A 1 338 ? 1.422   2.592   50.608 1.00 24.50 ?  304  GLU A H    1 
ATOM   4497  H HA   . GLU A 1 338 ? -1.042  1.755   50.259 1.00 24.81 ?  304  GLU A HA   1 
ATOM   4498  H HB2  . GLU A 1 338 ? -0.053  4.283   50.974 1.00 36.47 ?  304  GLU A HB2  1 
ATOM   4499  H HB3  . GLU A 1 338 ? -1.612  4.038   50.789 1.00 36.47 ?  304  GLU A HB3  1 
ATOM   4500  H HG2  . GLU A 1 338 ? -0.029  2.732   52.723 1.00 51.34 ?  304  GLU A HG2  1 
ATOM   4501  H HG3  . GLU A 1 338 ? -1.029  3.925   53.043 1.00 51.34 ?  304  GLU A HG3  1 
ATOM   4502  N N    . LEU A 1 339 ? 0.095   3.639   47.934 1.00 18.10 ?  305  LEU A N    1 
ATOM   4503  C CA   . LEU A 1 339 ? -0.167  3.994   46.546 1.00 17.41 ?  305  LEU A CA   1 
ATOM   4504  C C    . LEU A 1 339 ? -0.348  2.734   45.708 1.00 17.95 ?  305  LEU A C    1 
ATOM   4505  O O    . LEU A 1 339 ? -1.230  2.673   44.841 1.00 16.99 ?  305  LEU A O    1 
ATOM   4506  C CB   . LEU A 1 339 ? 0.971   4.849   45.983 1.00 19.03 ?  305  LEU A CB   1 
ATOM   4507  C CG   . LEU A 1 339 ? 0.856   5.223   44.496 1.00 19.27 ?  305  LEU A CG   1 
ATOM   4508  C CD1  . LEU A 1 339 ? -0.413  6.032   44.237 1.00 21.20 ?  305  LEU A CD1  1 
ATOM   4509  C CD2  . LEU A 1 339 ? 2.108   5.955   44.003 1.00 19.70 ?  305  LEU A CD2  1 
ATOM   4510  H H    . LEU A 1 339 ? 0.846   3.915   48.250 1.00 21.72 ?  305  LEU A H    1 
ATOM   4511  H HA   . LEU A 1 339 ? -0.977  4.526   46.501 1.00 20.90 ?  305  LEU A HA   1 
ATOM   4512  H HB2  . LEU A 1 339 ? 1.006   5.677   46.487 1.00 22.83 ?  305  LEU A HB2  1 
ATOM   4513  H HB3  . LEU A 1 339 ? 1.801   4.358   46.093 1.00 22.83 ?  305  LEU A HB3  1 
ATOM   4514  H HG   . LEU A 1 339 ? 0.791   4.407   43.977 1.00 23.13 ?  305  LEU A HG   1 
ATOM   4515  H HD11 . LEU A 1 339 ? -0.435  6.295   43.304 1.00 25.44 ?  305  LEU A HD11 1 
ATOM   4516  H HD12 . LEU A 1 339 ? -1.186  5.482   44.444 1.00 25.44 ?  305  LEU A HD12 1 
ATOM   4517  H HD13 . LEU A 1 339 ? -0.407  6.820   44.803 1.00 25.44 ?  305  LEU A HD13 1 
ATOM   4518  H HD21 . LEU A 1 339 ? 2.002   6.161   43.061 1.00 23.64 ?  305  LEU A HD21 1 
ATOM   4519  H HD22 . LEU A 1 339 ? 2.214   6.775   44.510 1.00 23.64 ?  305  LEU A HD22 1 
ATOM   4520  H HD23 . LEU A 1 339 ? 2.880   5.383   44.133 1.00 23.64 ?  305  LEU A HD23 1 
ATOM   4521  N N    . ASN A 1 340 ? 0.473   1.713   45.958 1.00 15.14 ?  306  ASN A N    1 
ATOM   4522  C CA   . ASN A 1 340 ? 0.373   0.491   45.160 1.00 15.32 ?  306  ASN A CA   1 
ATOM   4523  C C    . ASN A 1 340 ? -0.892  -0.300  45.472 1.00 18.07 ?  306  ASN A C    1 
ATOM   4524  O O    . ASN A 1 340 ? -1.412  -0.984  44.584 1.00 14.98 ?  306  ASN A O    1 
ATOM   4525  C CB   . ASN A 1 340 ? 1.655   -0.317  45.285 1.00 17.13 ?  306  ASN A CB   1 
ATOM   4526  C CG   . ASN A 1 340 ? 2.708   0.155   44.313 1.00 21.36 ?  306  ASN A CG   1 
ATOM   4527  O OD1  . ASN A 1 340 ? 2.841   -0.392  43.221 1.00 24.28 ?  306  ASN A OD1  1 
ATOM   4528  N ND2  . ASN A 1 340 ? 3.422   1.229   44.672 1.00 17.95 ?  306  ASN A ND2  1 
ATOM   4529  H H    . ASN A 1 340 ? 1.080   1.701   46.567 1.00 18.17 ?  306  ASN A H    1 
ATOM   4530  H HA   . ASN A 1 340 ? 0.299   0.717   44.220 1.00 18.39 ?  306  ASN A HA   1 
ATOM   4531  H HB2  . ASN A 1 340 ? 2.007   -0.222  46.184 1.00 20.55 ?  306  ASN A HB2  1 
ATOM   4532  H HB3  . ASN A 1 340 ? 1.465   -1.250  45.100 1.00 20.55 ?  306  ASN A HB3  1 
ATOM   4533  H HD21 . ASN A 1 340 ? 4.033   1.534   44.149 1.00 21.54 ?  306  ASN A HD21 1 
ATOM   4534  H HD22 . ASN A 1 340 ? 3.269   1.615   45.425 1.00 21.54 ?  306  ASN A HD22 1 
ATOM   4535  N N    . LYS A 1 341 ? -1.427  -0.199  46.689 1.00 17.65 ?  307  LYS A N    1 
ATOM   4536  C CA   . LYS A 1 341 ? -2.754  -0.749  46.960 1.00 16.33 ?  307  LYS A CA   1 
ATOM   4537  C C    . LYS A 1 341 ? -3.825  -0.046  46.130 1.00 16.73 ?  307  LYS A C    1 
ATOM   4538  O O    . LYS A 1 341 ? -4.791  -0.673  45.681 1.00 16.29 ?  307  LYS A O    1 
ATOM   4539  C CB   . LYS A 1 341 ? -3.080  -0.606  48.446 1.00 20.61 ?  307  LYS A CB   1 
ATOM   4540  C CG   . LYS A 1 341 ? -2.420  -1.636  49.342 1.00 26.81 ?  307  LYS A CG   1 
ATOM   4541  C CD   . LYS A 1 341 ? -2.998  -1.563  50.748 1.00 33.24 ?  307  LYS A CD   1 
ATOM   4542  C CE   . LYS A 1 341 ? -1.999  -2.016  51.793 1.00 38.60 ?  307  LYS A CE   1 
ATOM   4543  N NZ   . LYS A 1 341 ? -2.524  -1.774  53.170 1.00 45.50 ?  307  LYS A NZ   1 
ATOM   4544  H H    . LYS A 1 341 ? -1.049  0.176   47.364 1.00 21.18 ?  307  LYS A H    1 
ATOM   4545  H HA   . LYS A 1 341 ? -2.751  -1.691  46.728 1.00 19.60 ?  307  LYS A HA   1 
ATOM   4546  H HB2  . LYS A 1 341 ? -2.788  0.270   48.743 1.00 24.74 ?  307  LYS A HB2  1 
ATOM   4547  H HB3  . LYS A 1 341 ? -4.040  -0.691  48.561 1.00 24.74 ?  307  LYS A HB3  1 
ATOM   4548  H HG2  . LYS A 1 341 ? -2.578  -2.525  48.987 1.00 32.17 ?  307  LYS A HG2  1 
ATOM   4549  H HG3  . LYS A 1 341 ? -1.466  -1.463  49.389 1.00 32.17 ?  307  LYS A HG3  1 
ATOM   4550  H HD2  . LYS A 1 341 ? -3.247  -0.647  50.945 1.00 39.89 ?  307  LYS A HD2  1 
ATOM   4551  H HD3  . LYS A 1 341 ? -3.777  -2.138  50.804 1.00 39.89 ?  307  LYS A HD3  1 
ATOM   4552  H HE2  . LYS A 1 341 ? -1.831  -2.966  51.689 1.00 46.31 ?  307  LYS A HE2  1 
ATOM   4553  H HE3  . LYS A 1 341 ? -1.172  -1.520  51.687 1.00 46.31 ?  307  LYS A HE3  1 
ATOM   4554  H HZ1  . LYS A 1 341 ? -1.930  -2.047  53.774 1.00 54.60 ?  307  LYS A HZ1  1 
ATOM   4555  H HZ2  . LYS A 1 341 ? -2.679  -0.906  53.288 1.00 54.60 ?  307  LYS A HZ2  1 
ATOM   4556  H HZ3  . LYS A 1 341 ? -3.284  -2.223  53.289 1.00 54.60 ?  307  LYS A HZ3  1 
ATOM   4557  N N    . ARG A 1 342 ? -3.696  1.268   45.944 1.00 15.74 ?  308  ARG A N    1 
ATOM   4558  C CA   . ARG A 1 342 ? -4.644  1.993   45.106 1.00 14.76 ?  308  ARG A CA   1 
ATOM   4559  C C    . ARG A 1 342 ? -4.500  1.583   43.643 1.00 13.88 ?  308  ARG A C    1 
ATOM   4560  O O    . ARG A 1 342 ? -5.503  1.406   42.943 1.00 14.39 ?  308  ARG A O    1 
ATOM   4561  C CB   . ARG A 1 342 ? -4.414  3.495   45.271 1.00 16.10 ?  308  ARG A CB   1 
ATOM   4562  C CG   . ARG A 1 342 ? -5.432  4.375   44.587 1.00 17.11 ?  308  ARG A CG   1 
ATOM   4563  C CD   . ARG A 1 342 ? -6.851  4.106   45.027 1.00 21.42 ?  308  ARG A CD   1 
ATOM   4564  N NE   . ARG A 1 342 ? -7.803  4.977   44.345 1.00 23.79 ?  308  ARG A NE   1 
ATOM   4565  C CZ   . ARG A 1 342 ? -9.109  4.996   44.578 1.00 19.16 ?  308  ARG A CZ   1 
ATOM   4566  N NH1  . ARG A 1 342 ? -9.666  4.188   45.464 1.00 27.17 ?  308  ARG A NH1  1 
ATOM   4567  N NH2  . ARG A 1 342 ? -9.872  5.854   43.913 1.00 26.10 ?  308  ARG A NH2  1 
ATOM   4568  H H    . ARG A 1 342 ? -3.076  1.755   46.287 1.00 18.89 ?  308  ARG A H    1 
ATOM   4569  H HA   . ARG A 1 342 ? -5.551  1.789   45.385 1.00 17.72 ?  308  ARG A HA   1 
ATOM   4570  H HB2  . ARG A 1 342 ? -4.436  3.706   46.218 1.00 19.32 ?  308  ARG A HB2  1 
ATOM   4571  H HB3  . ARG A 1 342 ? -3.545  3.714   44.902 1.00 19.32 ?  308  ARG A HB3  1 
ATOM   4572  H HG2  . ARG A 1 342 ? -5.230  5.303   44.788 1.00 20.53 ?  308  ARG A HG2  1 
ATOM   4573  H HG3  . ARG A 1 342 ? -5.385  4.225   43.630 1.00 20.53 ?  308  ARG A HG3  1 
ATOM   4574  H HD2  . ARG A 1 342 ? -7.080  3.186   44.822 1.00 25.70 ?  308  ARG A HD2  1 
ATOM   4575  H HD3  . ARG A 1 342 ? -6.925  4.263   45.981 1.00 25.70 ?  308  ARG A HD3  1 
ATOM   4576  H HE   . ARG A 1 342 ? -7.496  5.517   43.750 1.00 28.55 ?  308  ARG A HE   1 
ATOM   4577  H HH11 . ARG A 1 342 ? -9.179  3.633   45.906 1.00 32.60 ?  308  ARG A HH11 1 
ATOM   4578  H HH12 . ARG A 1 342 ? -10.515 4.217   45.599 1.00 32.60 ?  308  ARG A HH12 1 
ATOM   4579  H HH21 . ARG A 1 342 ? -9.519  6.388   43.339 1.00 31.33 ?  308  ARG A HH21 1 
ATOM   4580  H HH22 . ARG A 1 342 ? -10.720 5.875   44.056 1.00 31.33 ?  308  ARG A HH22 1 
ATOM   4581  N N    . VAL A 1 343 ? -3.264  1.412   43.175 1.00 12.75 ?  309  VAL A N    1 
ATOM   4582  C CA   . VAL A 1 343 ? -3.037  0.924   41.820 1.00 12.28 ?  309  VAL A CA   1 
ATOM   4583  C C    . VAL A 1 343 ? -3.687  -0.437  41.641 1.00 15.25 ?  309  VAL A C    1 
ATOM   4584  O O    . VAL A 1 343 ? -4.374  -0.686  40.642 1.00 13.36 ?  309  VAL A O    1 
ATOM   4585  C CB   . VAL A 1 343 ? -1.531  0.897   41.514 1.00 12.32 ?  309  VAL A CB   1 
ATOM   4586  C CG1  . VAL A 1 343 ? -1.230  0.156   40.241 1.00 13.07 ?  309  VAL A CG1  1 
ATOM   4587  C CG2  . VAL A 1 343 ? -0.976  2.324   41.430 1.00 14.57 ?  309  VAL A CG2  1 
ATOM   4588  H H    . VAL A 1 343 ? -2.546  1.571   43.620 1.00 15.31 ?  309  VAL A H    1 
ATOM   4589  H HA   . VAL A 1 343 ? -3.453  1.531   41.188 1.00 14.74 ?  309  VAL A HA   1 
ATOM   4590  H HB   . VAL A 1 343 ? -1.093  0.426   42.240 1.00 14.78 ?  309  VAL A HB   1 
ATOM   4591  H HG11 . VAL A 1 343 ? -0.306  0.316   39.993 1.00 15.68 ?  309  VAL A HG11 1 
ATOM   4592  H HG12 . VAL A 1 343 ? -1.374  -0.793  40.386 1.00 15.68 ?  309  VAL A HG12 1 
ATOM   4593  H HG13 . VAL A 1 343 ? -1.821  0.477   39.541 1.00 15.68 ?  309  VAL A HG13 1 
ATOM   4594  H HG21 . VAL A 1 343 ? -0.027  2.283   41.234 1.00 17.49 ?  309  VAL A HG21 1 
ATOM   4595  H HG22 . VAL A 1 343 ? -1.439  2.803   40.725 1.00 17.49 ?  309  VAL A HG22 1 
ATOM   4596  H HG23 . VAL A 1 343 ? -1.118  2.769   42.281 1.00 17.49 ?  309  VAL A HG23 1 
ATOM   4597  N N    . ASP A 1 344 ? -3.494  -1.338  42.611 1.00 13.94 ?  310  ASP A N    1 
ATOM   4598  C CA   . ASP A 1 344 ? -4.125  -2.657  42.530 1.00 11.97 ?  310  ASP A CA   1 
ATOM   4599  C C    . ASP A 1 344 ? -5.641  -2.538  42.425 1.00 12.98 ?  310  ASP A C    1 
ATOM   4600  O O    . ASP A 1 344 ? -6.282  -3.267  41.659 1.00 12.64 ?  310  ASP A O    1 
ATOM   4601  C CB   . ASP A 1 344 ? -3.804  -3.474  43.782 1.00 11.99 ?  310  ASP A CB   1 
ATOM   4602  C CG   . ASP A 1 344 ? -2.379  -3.945  43.839 1.00 13.92 ?  310  ASP A CG   1 
ATOM   4603  O OD1  . ASP A 1 344 ? -1.638  -3.887  42.846 1.00 15.07 ?  310  ASP A OD1  1 
ATOM   4604  O OD2  . ASP A 1 344 ? -1.981  -4.384  44.948 1.00 16.80 ?  310  ASP A OD2  1 
ATOM   4605  H H    . ASP A 1 344 ? -3.011  -1.212  43.311 1.00 16.72 ?  310  ASP A H    1 
ATOM   4606  H HA   . ASP A 1 344 ? -3.774  -3.106  41.745 1.00 14.36 ?  310  ASP A HA   1 
ATOM   4607  H HB2  . ASP A 1 344 ? -3.967  -2.924  44.564 1.00 14.39 ?  310  ASP A HB2  1 
ATOM   4608  H HB3  . ASP A 1 344 ? -4.376  -4.256  43.800 1.00 14.39 ?  310  ASP A HB3  1 
ATOM   4609  N N    . TYR A 1 345 ? -6.241  -1.673  43.236 1.00 12.32 ?  311  TYR A N    1 
ATOM   4610  C CA   . TYR A 1 345 ? -7.686  -1.504  43.243 1.00 11.74 ?  311  TYR A CA   1 
ATOM   4611  C C    . TYR A 1 345 ? -8.197  -1.012  41.892 1.00 12.01 ?  311  TYR A C    1 
ATOM   4612  O O    . TYR A 1 345 ? -9.179  -1.540  41.358 1.00 11.94 ?  311  TYR A O    1 
ATOM   4613  C CB   . TYR A 1 345 ? -8.087  -0.523  44.352 1.00 13.25 ?  311  TYR A CB   1 
ATOM   4614  C CG   . TYR A 1 345 ? -9.562  -0.182  44.376 1.00 13.33 ?  311  TYR A CG   1 
ATOM   4615  C CD1  . TYR A 1 345 ? -10.511 -1.136  44.697 1.00 15.18 ?  311  TYR A CD1  1 
ATOM   4616  C CD2  . TYR A 1 345 ? -10.012 1.101   44.063 1.00 14.56 ?  311  TYR A CD2  1 
ATOM   4617  C CE1  . TYR A 1 345 ? -11.855 -0.833  44.706 1.00 16.22 ?  311  TYR A CE1  1 
ATOM   4618  C CE2  . TYR A 1 345 ? -11.370 1.416   44.089 1.00 15.83 ?  311  TYR A CE2  1 
ATOM   4619  C CZ   . TYR A 1 345 ? -12.290 0.440   44.408 1.00 14.79 ?  311  TYR A CZ   1 
ATOM   4620  O OH   . TYR A 1 345 ? -13.642 0.697   44.447 1.00 19.23 ?  311  TYR A OH   1 
ATOM   4621  H H    . TYR A 1 345 ? -5.829  -1.166  43.796 1.00 14.78 ?  311  TYR A H    1 
ATOM   4622  H HA   . TYR A 1 345 ? -8.097  -2.363  43.423 1.00 14.09 ?  311  TYR A HA   1 
ATOM   4623  H HB2  . TYR A 1 345 ? -7.862  -0.916  45.210 1.00 15.90 ?  311  TYR A HB2  1 
ATOM   4624  H HB3  . TYR A 1 345 ? -7.596  0.305   44.227 1.00 15.90 ?  311  TYR A HB3  1 
ATOM   4625  H HD1  . TYR A 1 345 ? -10.237 -1.999  44.911 1.00 18.22 ?  311  TYR A HD1  1 
ATOM   4626  H HD2  . TYR A 1 345 ? -9.395  1.757   43.833 1.00 17.47 ?  311  TYR A HD2  1 
ATOM   4627  H HE1  . TYR A 1 345 ? -12.475 -1.494  44.916 1.00 19.46 ?  311  TYR A HE1  1 
ATOM   4628  H HE2  . TYR A 1 345 ? -11.654 2.279   43.892 1.00 18.99 ?  311  TYR A HE2  1 
ATOM   4629  H HH   . TYR A 1 345 ? -13.789 1.495   44.230 1.00 23.08 ?  311  TYR A HH   1 
ATOM   4630  N N    . LEU A 1 346 ? -7.571  0.032   41.349 1.00 11.27 ?  312  LEU A N    1 
ATOM   4631  C CA   . LEU A 1 346 ? -8.033  0.576   40.079 1.00 11.59 ?  312  LEU A CA   1 
ATOM   4632  C C    . LEU A 1 346 ? -7.814  -0.414  38.945 1.00 11.25 ?  312  LEU A C    1 
ATOM   4633  O O    . LEU A 1 346 ? -8.674  -0.562  38.061 1.00 11.31 ?  312  LEU A O    1 
ATOM   4634  C CB   . LEU A 1 346 ? -7.320  1.895   39.804 1.00 11.49 ?  312  LEU A CB   1 
ATOM   4635  C CG   . LEU A 1 346 ? -7.619  2.988   40.828 1.00 11.24 ?  312  LEU A CG   1 
ATOM   4636  C CD1  . LEU A 1 346 ? -6.791  4.228   40.491 1.00 13.96 ?  312  LEU A CD1  1 
ATOM   4637  C CD2  . LEU A 1 346 ? -9.083  3.353   40.874 1.00 14.44 ?  312  LEU A CD2  1 
ATOM   4638  H H    . LEU A 1 346 ? -6.891  0.434   41.690 1.00 13.52 ?  312  LEU A H    1 
ATOM   4639  H HA   . LEU A 1 346 ? -8.985  0.754   40.130 1.00 13.91 ?  312  LEU A HA   1 
ATOM   4640  H HB2  . LEU A 1 346 ? -6.363  1.738   39.810 1.00 13.78 ?  312  LEU A HB2  1 
ATOM   4641  H HB3  . LEU A 1 346 ? -7.596  2.222   38.933 1.00 13.78 ?  312  LEU A HB3  1 
ATOM   4642  H HG   . LEU A 1 346 ? -7.385  2.653   41.708 1.00 13.48 ?  312  LEU A HG   1 
ATOM   4643  H HD11 . LEU A 1 346 ? -6.981  4.922   41.142 1.00 16.76 ?  312  LEU A HD11 1 
ATOM   4644  H HD12 . LEU A 1 346 ? -5.850  3.997   40.519 1.00 16.76 ?  312  LEU A HD12 1 
ATOM   4645  H HD13 . LEU A 1 346 ? -7.029  4.536   39.602 1.00 16.76 ?  312  LEU A HD13 1 
ATOM   4646  H HD21 . LEU A 1 346 ? -9.200  4.117   41.460 1.00 17.32 ?  312  LEU A HD21 1 
ATOM   4647  H HD22 . LEU A 1 346 ? -9.382  3.574   39.978 1.00 17.32 ?  312  LEU A HD22 1 
ATOM   4648  H HD23 . LEU A 1 346 ? -9.586  2.596   41.213 1.00 17.32 ?  312  LEU A HD23 1 
ATOM   4649  N N    . LEU A 1 347 ? -6.679  -1.106  38.946 1.00 10.82 ?  313  LEU A N    1 
ATOM   4650  C CA   . LEU A 1 347 ? -6.472  -2.136  37.936 1.00 9.82  ?  313  LEU A CA   1 
ATOM   4651  C C    . LEU A 1 347 ? -7.470  -3.272  38.087 1.00 12.93 ?  313  LEU A C    1 
ATOM   4652  O O    . LEU A 1 347 ? -7.893  -3.849  37.084 1.00 11.35 ?  313  LEU A O    1 
ATOM   4653  C CB   . LEU A 1 347 ? -5.052  -2.685  37.982 1.00 10.74 ?  313  LEU A CB   1 
ATOM   4654  C CG   . LEU A 1 347 ? -3.953  -1.720  37.546 1.00 11.75 ?  313  LEU A CG   1 
ATOM   4655  C CD1  . LEU A 1 347 ? -2.590  -2.374  37.702 1.00 13.04 ?  313  LEU A CD1  1 
ATOM   4656  C CD2  . LEU A 1 347 ? -4.172  -1.279  36.096 1.00 13.62 ?  313  LEU A CD2  1 
ATOM   4657  H H    . LEU A 1 347 ? -6.032  -1.003  39.504 1.00 12.98 ?  313  LEU A H    1 
ATOM   4658  H HA   . LEU A 1 347 ? -6.595  -1.724  37.066 1.00 11.79 ?  313  LEU A HA   1 
ATOM   4659  H HB2  . LEU A 1 347 ? -4.858  -2.949  38.896 1.00 12.88 ?  313  LEU A HB2  1 
ATOM   4660  H HB3  . LEU A 1 347 ? -5.006  -3.457  37.397 1.00 12.88 ?  313  LEU A HB3  1 
ATOM   4661  H HG   . LEU A 1 347 ? -3.979  -0.929  38.108 1.00 14.10 ?  313  LEU A HG   1 
ATOM   4662  H HD11 . LEU A 1 347 ? -1.910  -1.774  37.356 1.00 15.65 ?  313  LEU A HD11 1 
ATOM   4663  H HD12 . LEU A 1 347 ? -2.429  -2.548  38.642 1.00 15.65 ?  313  LEU A HD12 1 
ATOM   4664  H HD13 . LEU A 1 347 ? -2.581  -3.207  37.205 1.00 15.65 ?  313  LEU A HD13 1 
ATOM   4665  H HD21 . LEU A 1 347 ? -3.388  -0.797  35.791 1.00 16.35 ?  313  LEU A HD21 1 
ATOM   4666  H HD22 . LEU A 1 347 ? -4.313  -2.065  35.545 1.00 16.35 ?  313  LEU A HD22 1 
ATOM   4667  H HD23 . LEU A 1 347 ? -4.951  -0.703  36.056 1.00 16.35 ?  313  LEU A HD23 1 
ATOM   4668  N N    . ALA A 1 348 ? -7.858  -3.615  39.316 1.00 10.75 ?  314  ALA A N    1 
ATOM   4669  C CA   . ALA A 1 348 ? -8.850  -4.660  39.497 1.00 11.71 ?  314  ALA A CA   1 
ATOM   4670  C C    . ALA A 1 348 ? -10.180 -4.270  38.878 1.00 11.13 ?  314  ALA A C    1 
ATOM   4671  O O    . ALA A 1 348 ? -10.843 -5.104  38.253 1.00 10.51 ?  314  ALA A O    1 
ATOM   4672  C CB   . ALA A 1 348 ? -9.007  -5.016  40.977 1.00 13.09 ?  314  ALA A CB   1 
ATOM   4673  H H    . ALA A 1 348 ? -7.566  -3.262  40.043 1.00 12.90 ?  314  ALA A H    1 
ATOM   4674  H HA   . ALA A 1 348 ? -8.537  -5.461  39.048 1.00 14.05 ?  314  ALA A HA   1 
ATOM   4675  H HB1  . ALA A 1 348 ? -9.664  -5.725  41.064 1.00 15.71 ?  314  ALA A HB1  1 
ATOM   4676  H HB2  . ALA A 1 348 ? -8.151  -5.313  41.323 1.00 15.71 ?  314  ALA A HB2  1 
ATOM   4677  H HB3  . ALA A 1 348 ? -9.305  -4.230  41.461 1.00 15.71 ?  314  ALA A HB3  1 
ATOM   4678  N N    . ILE A 1 349 ? -10.593 -3.012  39.037 1.00 10.74 ?  315  ILE A N    1 
ATOM   4679  C CA   . ILE A 1 349 ? -11.816 -2.557  38.388 1.00 9.51  ?  315  ILE A CA   1 
ATOM   4680  C C    . ILE A 1 349 ? -11.708 -2.764  36.881 1.00 10.41 ?  315  ILE A C    1 
ATOM   4681  O O    . ILE A 1 349 ? -12.621 -3.305  36.243 1.00 10.90 ?  315  ILE A O    1 
ATOM   4682  C CB   . ILE A 1 349 ? -12.080 -1.076  38.718 1.00 9.77  ?  315  ILE A CB   1 
ATOM   4683  C CG1  . ILE A 1 349 ? -12.499 -0.902  40.180 1.00 12.62 ?  315  ILE A CG1  1 
ATOM   4684  C CG2  . ILE A 1 349 ? -13.165 -0.516  37.792 1.00 11.77 ?  315  ILE A CG2  1 
ATOM   4685  C CD1  . ILE A 1 349 ? -12.546 0.543   40.682 1.00 13.72 ?  315  ILE A CD1  1 
ATOM   4686  H H    . ILE A 1 349 ? -10.189 -2.415  39.507 1.00 12.89 ?  315  ILE A H    1 
ATOM   4687  H HA   . ILE A 1 349 ? -12.559 -3.082  38.724 1.00 11.41 ?  315  ILE A HA   1 
ATOM   4688  H HB   . ILE A 1 349 ? -11.254 -0.587  38.580 1.00 11.72 ?  315  ILE A HB   1 
ATOM   4689  H HG12 . ILE A 1 349 ? -13.388 -1.275  40.290 1.00 15.14 ?  315  ILE A HG12 1 
ATOM   4690  H HG13 . ILE A 1 349 ? -11.867 -1.381  40.738 1.00 15.14 ?  315  ILE A HG13 1 
ATOM   4691  H HG21 . ILE A 1 349 ? -13.444 0.353   38.121 1.00 14.13 ?  315  ILE A HG21 1 
ATOM   4692  H HG22 . ILE A 1 349 ? -12.803 -0.431  36.897 1.00 14.13 ?  315  ILE A HG22 1 
ATOM   4693  H HG23 . ILE A 1 349 ? -13.920 -1.125  37.786 1.00 14.13 ?  315  ILE A HG23 1 
ATOM   4694  H HD11 . ILE A 1 349 ? -12.774 0.542   41.625 1.00 16.46 ?  315  ILE A HD11 1 
ATOM   4695  H HD12 . ILE A 1 349 ? -11.676 0.951   40.553 1.00 16.46 ?  315  ILE A HD12 1 
ATOM   4696  H HD13 . ILE A 1 349 ? -13.218 1.030   40.180 1.00 16.46 ?  315  ILE A HD13 1 
ATOM   4697  N N    . PHE A 1 350 ? -10.581 -2.334  36.296 1.00 8.66  ?  316  PHE A N    1 
ATOM   4698  C CA   . PHE A 1 350 ? -10.350 -2.513  34.862 1.00 9.30  ?  316  PHE A CA   1 
ATOM   4699  C C    . PHE A 1 350 ? -10.407 -3.985  34.474 1.00 9.29  ?  316  PHE A C    1 
ATOM   4700  O O    . PHE A 1 350 ? -11.100 -4.355  33.516 1.00 9.71  ?  316  PHE A O    1 
ATOM   4701  C CB   . PHE A 1 350 ? -9.005  -1.898  34.467 1.00 10.14 ?  316  PHE A CB   1 
ATOM   4702  C CG   . PHE A 1 350 ? -8.578  -2.250  33.079 1.00 9.25  ?  316  PHE A CG   1 
ATOM   4703  C CD1  . PHE A 1 350 ? -9.251  -1.740  31.995 1.00 9.17  ?  316  PHE A CD1  1 
ATOM   4704  C CD2  . PHE A 1 350 ? -7.509  -3.101  32.853 1.00 10.28 ?  316  PHE A CD2  1 
ATOM   4705  C CE1  . PHE A 1 350 ? -8.864  -2.073  30.710 1.00 9.26  ?  316  PHE A CE1  1 
ATOM   4706  C CE2  . PHE A 1 350 ? -7.125  -3.425  31.559 1.00 9.67  ?  316  PHE A CE2  1 
ATOM   4707  C CZ   . PHE A 1 350 ? -7.807  -2.910  30.487 1.00 8.70  ?  316  PHE A CZ   1 
ATOM   4708  H H    . PHE A 1 350 ? -9.939  -1.936  36.707 1.00 10.39 ?  316  PHE A H    1 
ATOM   4709  H HA   . PHE A 1 350 ? -11.047 -2.049  34.372 1.00 11.16 ?  316  PHE A HA   1 
ATOM   4710  H HB2  . PHE A 1 350 ? -9.074  -0.932  34.522 1.00 12.17 ?  316  PHE A HB2  1 
ATOM   4711  H HB3  . PHE A 1 350 ? -8.323  -2.217  35.078 1.00 12.17 ?  316  PHE A HB3  1 
ATOM   4712  H HD1  . PHE A 1 350 ? -9.972  -1.167  32.126 1.00 11.00 ?  316  PHE A HD1  1 
ATOM   4713  H HD2  . PHE A 1 350 ? -7.044  -3.458  33.574 1.00 12.33 ?  316  PHE A HD2  1 
ATOM   4714  H HE1  . PHE A 1 350 ? -9.330  -1.722  29.987 1.00 11.12 ?  316  PHE A HE1  1 
ATOM   4715  H HE2  . PHE A 1 350 ? -6.403  -3.994  31.419 1.00 11.60 ?  316  PHE A HE2  1 
ATOM   4716  H HZ   . PHE A 1 350 ? -7.554  -3.128  29.619 1.00 10.44 ?  316  PHE A HZ   1 
ATOM   4717  N N    . LEU A 1 351 ? -9.700  -4.851  35.220 1.00 9.43  ?  317  LEU A N    1 
ATOM   4718  C CA   . LEU A 1 351 ? -9.593  -6.260  34.828 1.00 9.64  ?  317  LEU A CA   1 
ATOM   4719  C C    . LEU A 1 351 ? -10.909 -7.005  34.981 1.00 9.95  ?  317  LEU A C    1 
ATOM   4720  O O    . LEU A 1 351 ? -11.138 -7.989  34.269 1.00 10.61 ?  317  LEU A O    1 
ATOM   4721  C CB   . LEU A 1 351 ? -8.479  -6.937  35.613 1.00 10.96 ?  317  LEU A CB   1 
ATOM   4722  C CG   . LEU A 1 351 ? -7.072  -6.475  35.254 1.00 11.31 ?  317  LEU A CG   1 
ATOM   4723  C CD1  . LEU A 1 351 ? -6.090  -7.002  36.293 1.00 15.03 ?  317  LEU A CD1  1 
ATOM   4724  C CD2  . LEU A 1 351 ? -6.696  -6.926  33.850 1.00 13.24 ?  317  LEU A CD2  1 
ATOM   4725  H H    . LEU A 1 351 ? -9.281  -4.650  35.944 1.00 11.32 ?  317  LEU A H    1 
ATOM   4726  H HA   . LEU A 1 351 ? -9.357  -6.302  33.888 1.00 11.57 ?  317  LEU A HA   1 
ATOM   4727  H HB2  . LEU A 1 351 ? -8.614  -6.755  36.556 1.00 13.15 ?  317  LEU A HB2  1 
ATOM   4728  H HB3  . LEU A 1 351 ? -8.524  -7.892  35.449 1.00 13.15 ?  317  LEU A HB3  1 
ATOM   4729  H HG   . LEU A 1 351 ? -7.030  -5.506  35.256 1.00 13.57 ?  317  LEU A HG   1 
ATOM   4730  H HD11 . LEU A 1 351 ? -5.195  -6.988  35.919 1.00 18.04 ?  317  LEU A HD11 1 
ATOM   4731  H HD12 . LEU A 1 351 ? -6.128  -6.436  37.080 1.00 18.04 ?  317  LEU A HD12 1 
ATOM   4732  H HD13 . LEU A 1 351 ? -6.335  -7.911  36.528 1.00 18.04 ?  317  LEU A HD13 1 
ATOM   4733  H HD21 . LEU A 1 351 ? -5.775  -6.680  33.675 1.00 15.89 ?  317  LEU A HD21 1 
ATOM   4734  H HD22 . LEU A 1 351 ? -6.798  -7.889  33.791 1.00 15.89 ?  317  LEU A HD22 1 
ATOM   4735  H HD23 . LEU A 1 351 ? -7.282  -6.492  33.211 1.00 15.89 ?  317  LEU A HD23 1 
ATOM   4736  N N    . ILE A 1 352 ? -11.778 -6.570  35.890 1.00 9.80  ?  318  ILE A N    1 
ATOM   4737  C CA   . ILE A 1 352 ? -13.115 -7.136  36.011 1.00 10.77 ?  318  ILE A CA   1 
ATOM   4738  C C    . ILE A 1 352 ? -13.941 -6.888  34.750 1.00 11.54 ?  318  ILE A C    1 
ATOM   4739  O O    . ILE A 1 352 ? -14.873 -7.653  34.456 1.00 10.87 ?  318  ILE A O    1 
ATOM   4740  C CB   . ILE A 1 352 ? -13.808 -6.583  37.280 1.00 13.59 ?  318  ILE A CB   1 
ATOM   4741  C CG1  . ILE A 1 352 ? -13.287 -7.249  38.572 1.00 17.82 ?  318  ILE A CG1  1 
ATOM   4742  C CG2  . ILE A 1 352 ? -15.338 -6.684  37.192 1.00 18.93 ?  318  ILE A CG2  1 
ATOM   4743  C CD1  . ILE A 1 352 ? -12.995 -8.711  38.516 1.00 20.91 ?  318  ILE A CD1  1 
ATOM   4744  H H    . ILE A 1 352 ? -11.616 -5.942  36.454 1.00 11.76 ?  318  ILE A H    1 
ATOM   4745  H HA   . ILE A 1 352 ? -13.044 -8.097  36.117 1.00 12.92 ?  318  ILE A HA   1 
ATOM   4746  H HB   . ILE A 1 352 ? -13.572 -5.643  37.323 1.00 16.31 ?  318  ILE A HB   1 
ATOM   4747  H HG12 . ILE A 1 352 ? -12.462 -6.807  38.824 1.00 21.38 ?  318  ILE A HG12 1 
ATOM   4748  H HG13 . ILE A 1 352 ? -13.956 -7.123  39.263 1.00 21.38 ?  318  ILE A HG13 1 
ATOM   4749  H HG21 . ILE A 1 352 ? -15.721 -6.415  38.042 1.00 22.72 ?  318  ILE A HG21 1 
ATOM   4750  H HG22 . ILE A 1 352 ? -15.653 -6.097  36.487 1.00 22.72 ?  318  ILE A HG22 1 
ATOM   4751  H HG23 . ILE A 1 352 ? -15.583 -7.601  36.994 1.00 22.72 ?  318  ILE A HG23 1 
ATOM   4752  H HD11 . ILE A 1 352 ? -12.804 -9.030  39.412 1.00 25.09 ?  318  ILE A HD11 1 
ATOM   4753  H HD12 . ILE A 1 352 ? -13.768 -9.175  38.158 1.00 25.09 ?  318  ILE A HD12 1 
ATOM   4754  H HD13 . ILE A 1 352 ? -12.226 -8.858  37.942 1.00 25.09 ?  318  ILE A HD13 1 
ATOM   4755  N N    . CYS A 1 353 ? -13.599 -5.854  33.970 1.00 10.03 ?  319  CYS A N    1 
ATOM   4756  C CA   . CYS A 1 353 ? -14.348 -5.498  32.772 1.00 9.79  ?  319  CYS A CA   1 
ATOM   4757  C C    . CYS A 1 353 ? -13.697 -5.951  31.475 1.00 9.83  ?  319  CYS A C    1 
ATOM   4758  O O    . CYS A 1 353 ? -14.401 -6.152  30.484 1.00 10.65 ?  319  CYS A O    1 
ATOM   4759  C CB   . CYS A 1 353 ? -14.450 -3.968  32.670 1.00 10.45 ?  319  CYS A CB   1 
ATOM   4760  S SG   . CYS A 1 353 ? -15.320 -3.164  34.027 1.00 11.46 ?  319  CYS A SG   1 
ATOM   4761  H H    . CYS A 1 353 ? -12.925 -5.341  34.121 1.00 12.03 ?  319  CYS A H    1 
ATOM   4762  H HA   . CYS A 1 353 ? -15.226 -5.903  32.847 1.00 11.74 ?  319  CYS A HA   1 
ATOM   4763  H HB2  . CYS A 1 353 ? -13.551 -3.603  32.645 1.00 12.54 ?  319  CYS A HB2  1 
ATOM   4764  H HB3  . CYS A 1 353 ? -14.920 -3.747  31.852 1.00 12.54 ?  319  CYS A HB3  1 
ATOM   4765  H HG   . CYS A 1 353 ? -14.716 -3.354  35.046 1.00 13.75 ?  319  CYS A HG   1 
ATOM   4766  N N    . ALA A 1 354 ? -12.379 -6.080  31.450 1.00 9.04  ?  320  ALA A N    1 
ATOM   4767  C CA   . ALA A 1 354 ? -11.611 -6.093  30.211 1.00 10.19 ?  320  ALA A CA   1 
ATOM   4768  C C    . ALA A 1 354 ? -11.936 -7.270  29.300 1.00 9.09  ?  320  ALA A C    1 
ATOM   4769  O O    . ALA A 1 354 ? -12.164 -8.404  29.742 1.00 10.46 ?  320  ALA A O    1 
ATOM   4770  C CB   . ALA A 1 354 ? -10.123 -6.138  30.534 1.00 10.93 ?  320  ALA A CB   1 
ATOM   4771  H H    . ALA A 1 354 ? -11.891 -6.164  32.153 1.00 10.85 ?  320  ALA A H    1 
ATOM   4772  H HA   . ALA A 1 354 ? -11.839 -5.286  29.724 1.00 12.22 ?  320  ALA A HA   1 
ATOM   4773  H HB1  . ALA A 1 354 ? -9.619  -6.099  29.706 1.00 13.11 ?  320  ALA A HB1  1 
ATOM   4774  H HB2  . ALA A 1 354 ? -9.898  -5.378  31.094 1.00 13.11 ?  320  ALA A HB2  1 
ATOM   4775  H HB3  . ALA A 1 354 ? -9.926  -6.964  31.003 1.00 13.11 ?  320  ALA A HB3  1 
ATOM   4776  N N    . GLU A 1 355 ? -11.867 -7.002  27.999 1.00 8.97  ?  321  GLU A N    1 
ATOM   4777  C CA   . GLU A 1 355 ? -11.830 -8.010  26.940 1.00 7.94  ?  321  GLU A CA   1 
ATOM   4778  C C    . GLU A 1 355 ? -10.734 -7.615  25.961 1.00 9.68  ?  321  GLU A C    1 
ATOM   4779  O O    . GLU A 1 355 ? -10.046 -6.608  26.144 1.00 9.59  ?  321  GLU A O    1 
ATOM   4780  C CB   . GLU A 1 355 ? -13.182 -8.136  26.233 1.00 10.42 ?  321  GLU A CB   1 
ATOM   4781  C CG   . GLU A 1 355 ? -14.320 -8.573  27.126 1.00 10.18 ?  321  GLU A CG   1 
ATOM   4782  C CD   . GLU A 1 355 ? -14.214 -10.023 27.582 1.00 12.84 ?  321  GLU A CD   1 
ATOM   4783  O OE1  . GLU A 1 355 ? -13.527 -10.808 26.889 1.00 16.34 ?  321  GLU A OE1  1 
ATOM   4784  O OE2  . GLU A 1 355 ? -14.798 -10.346 28.640 1.00 13.18 ?  321  GLU A OE2  1 
ATOM   4785  H H    . GLU A 1 355 ? -11.840 -6.201  27.688 1.00 10.76 ?  321  GLU A H    1 
ATOM   4786  H HA   . GLU A 1 355 ? -11.621 -8.877  27.320 1.00 9.53  ?  321  GLU A HA   1 
ATOM   4787  H HB2  . GLU A 1 355 ? -13.417 -7.272  25.860 1.00 12.50 ?  321  GLU A HB2  1 
ATOM   4788  H HB3  . GLU A 1 355 ? -13.098 -8.792  25.523 1.00 12.50 ?  321  GLU A HB3  1 
ATOM   4789  H HG2  . GLU A 1 355 ? -14.330 -8.013  27.917 1.00 12.22 ?  321  GLU A HG2  1 
ATOM   4790  H HG3  . GLU A 1 355 ? -15.154 -8.476  26.640 1.00 12.22 ?  321  GLU A HG3  1 
ATOM   4791  N N    . LYS A 1 356 ? -10.539 -8.410  24.919 1.00 9.49  ?  322  LYS A N    1 
ATOM   4792  C CA   . LYS A 1 356 ? -9.668  -8.020  23.834 1.00 10.58 ?  322  LYS A CA   1 
ATOM   4793  C C    . LYS A 1 356 ? -10.014 -6.593  23.414 1.00 8.43  ?  322  LYS A C    1 
ATOM   4794  O O    . LYS A 1 356 ? -11.181 -6.252  23.265 1.00 9.39  ?  322  LYS A O    1 
ATOM   4795  C CB   . LYS A 1 356 ? -9.868  -9.010  22.683 1.00 13.91 ?  322  LYS A CB   1 
ATOM   4796  C CG   . LYS A 1 356 ? -8.939  -8.783  21.542 1.00 12.99 ?  322  LYS A CG   1 
ATOM   4797  C CD   . LYS A 1 356 ? -9.053  -9.902  20.511 1.00 10.58 ?  322  LYS A CD   1 
ATOM   4798  C CE   . LYS A 1 356 ? -10.462 -10.063 19.958 1.00 11.74 ?  322  LYS A CE   1 
ATOM   4799  N NZ   . LYS A 1 356 ? -10.439 -11.023 18.786 1.00 10.31 ?  322  LYS A NZ   1 
ATOM   4800  H H    . LYS A 1 356 ? -10.903 -9.183  24.820 1.00 11.39 ?  322  LYS A H    1 
ATOM   4801  H HA   . LYS A 1 356 ? -8.733  -8.041  24.089 1.00 12.70 ?  322  LYS A HA   1 
ATOM   4802  H HB2  . LYS A 1 356 ? -9.718  -9.909  23.015 1.00 16.69 ?  322  LYS A HB2  1 
ATOM   4803  H HB3  . LYS A 1 356 ? -10.775 -8.925  22.351 1.00 16.69 ?  322  LYS A HB3  1 
ATOM   4804  H HG2  . LYS A 1 356 ? -9.158  -7.943  21.109 1.00 15.59 ?  322  LYS A HG2  1 
ATOM   4805  H HG3  . LYS A 1 356 ? -8.026  -8.759  21.869 1.00 15.59 ?  322  LYS A HG3  1 
ATOM   4806  H HD2  . LYS A 1 356 ? -8.462  -9.706  19.767 1.00 12.70 ?  322  LYS A HD2  1 
ATOM   4807  H HD3  . LYS A 1 356 ? -8.798  -10.740 20.926 1.00 12.70 ?  322  LYS A HD3  1 
ATOM   4808  H HE2  . LYS A 1 356 ? -11.045 -10.422 20.645 1.00 14.08 ?  322  LYS A HE2  1 
ATOM   4809  H HE3  . LYS A 1 356 ? -10.796 -9.205  19.653 1.00 14.08 ?  322  LYS A HE3  1 
ATOM   4810  H HZ1  . LYS A 1 356 ? -10.131 -11.815 19.048 1.00 12.37 ?  322  LYS A HZ1  1 
ATOM   4811  H HZ2  . LYS A 1 356 ? -11.261 -11.126 18.461 1.00 12.37 ?  322  LYS A HZ2  1 
ATOM   4812  H HZ3  . LYS A 1 356 ? -9.912  -10.706 18.143 1.00 12.37 ?  322  LYS A HZ3  1 
ATOM   4813  N N    . TYR A 1 357 ? -8.981  -5.755  23.269 1.00 8.13  ?  323  TYR A N    1 
ATOM   4814  C CA   . TYR A 1 357 ? -9.079  -4.341  22.869 1.00 8.28  ?  323  TYR A CA   1 
ATOM   4815  C C    . TYR A 1 357 ? -9.549  -3.433  23.991 1.00 9.13  ?  323  TYR A C    1 
ATOM   4816  O O    . TYR A 1 357 ? -9.998  -2.309  23.724 1.00 9.22  ?  323  TYR A O    1 
ATOM   4817  C CB   . TYR A 1 357 ? -9.884  -4.136  21.586 1.00 10.20 ?  323  TYR A CB   1 
ATOM   4818  C CG   . TYR A 1 357 ? -9.339  -4.948  20.423 1.00 9.44  ?  323  TYR A CG   1 
ATOM   4819  C CD1  . TYR A 1 357 ? -8.045  -4.788  19.993 1.00 9.70  ?  323  TYR A CD1  1 
ATOM   4820  C CD2  . TYR A 1 357 ? -10.136 -5.874  19.766 1.00 11.23 ?  323  TYR A CD2  1 
ATOM   4821  C CE1  . TYR A 1 357 ? -7.536  -5.521  18.944 1.00 10.07 ?  323  TYR A CE1  1 
ATOM   4822  C CE2  . TYR A 1 357 ? -9.636  -6.612  18.693 1.00 11.45 ?  323  TYR A CE2  1 
ATOM   4823  C CZ   . TYR A 1 357 ? -8.349  -6.450  18.311 1.00 9.96  ?  323  TYR A CZ   1 
ATOM   4824  O OH   . TYR A 1 357 ? -7.840  -7.151  17.231 1.00 12.35 ?  323  TYR A OH   1 
ATOM   4825  H H    . TYR A 1 357 ? -8.166  -5.996  23.404 1.00 9.75  ?  323  TYR A H    1 
ATOM   4826  H HA   . TYR A 1 357 ? -8.182  -4.039  22.656 1.00 9.93  ?  323  TYR A HA   1 
ATOM   4827  H HB2  . TYR A 1 357 ? -10.802 -4.409  21.741 1.00 12.24 ?  323  TYR A HB2  1 
ATOM   4828  H HB3  . TYR A 1 357 ? -9.853  -3.198  21.340 1.00 12.24 ?  323  TYR A HB3  1 
ATOM   4829  H HD1  . TYR A 1 357 ? -7.499  -4.169  20.421 1.00 11.64 ?  323  TYR A HD1  1 
ATOM   4830  H HD2  . TYR A 1 357 ? -11.014 -6.005  20.044 1.00 13.47 ?  323  TYR A HD2  1 
ATOM   4831  H HE1  . TYR A 1 357 ? -6.659  -5.395  18.664 1.00 12.08 ?  323  TYR A HE1  1 
ATOM   4832  H HE2  . TYR A 1 357 ? -10.185 -7.212  18.242 1.00 13.74 ?  323  TYR A HE2  1 
ATOM   4833  H HH   . TYR A 1 357 ? -7.004  -7.080  17.211 1.00 14.82 ?  323  TYR A HH   1 
ATOM   4834  N N    . SER A 1 358 ? -9.417  -3.874  25.238 1.00 8.71  ?  324  SER A N    1 
ATOM   4835  C CA   . SER A 1 358 ? -9.559  -3.012  26.402 1.00 8.33  ?  324  SER A CA   1 
ATOM   4836  C C    . SER A 1 358 ? -8.184  -2.599  26.894 1.00 8.98  ?  324  SER A C    1 
ATOM   4837  O O    . SER A 1 358 ? -7.292  -3.442  27.020 1.00 9.17  ?  324  SER A O    1 
ATOM   4838  C CB   . SER A 1 358 ? -10.266 -3.770  27.519 1.00 8.49  ?  324  SER A CB   1 
ATOM   4839  O OG   . SER A 1 358 ? -11.634 -4.069  27.233 1.00 8.91  ?  324  SER A OG   1 
ATOM   4840  H H    . SER A 1 358 ? -9.240  -4.691  25.439 1.00 10.46 ?  324  SER A H    1 
ATOM   4841  H HA   . SER A 1 358 ? -10.065 -2.219  26.164 1.00 9.99  ?  324  SER A HA   1 
ATOM   4842  H HB2  . SER A 1 358 ? -9.796  -4.605  27.665 1.00 10.19 ?  324  SER A HB2  1 
ATOM   4843  H HB3  . SER A 1 358 ? -10.235 -3.227  28.322 1.00 10.19 ?  324  SER A HB3  1 
ATOM   4844  H HG   . SER A 1 358 ? -11.799 -3.913  26.424 1.00 10.70 ?  324  SER A HG   1 
ATOM   4845  N N    . TYR A 1 359 ? -8.028  -1.310  27.203 1.00 9.01  ?  325  TYR A N    1 
ATOM   4846  C CA   . TYR A 1 359 ? -6.758  -0.725  27.618 1.00 7.77  ?  325  TYR A CA   1 
ATOM   4847  C C    . TYR A 1 359 ? -7.005  0.228   28.776 1.00 8.49  ?  325  TYR A C    1 
ATOM   4848  O O    . TYR A 1 359 ? -8.073  0.837   28.867 1.00 8.67  ?  325  TYR A O    1 
ATOM   4849  C CB   . TYR A 1 359 ? -6.146  0.079   26.450 1.00 7.87  ?  325  TYR A CB   1 
ATOM   4850  C CG   . TYR A 1 359 ? -5.995  -0.687  25.141 1.00 7.43  ?  325  TYR A CG   1 
ATOM   4851  C CD1  . TYR A 1 359 ? -7.033  -0.731  24.216 1.00 8.72  ?  325  TYR A CD1  1 
ATOM   4852  C CD2  . TYR A 1 359 ? -4.810  -1.326  24.832 1.00 8.79  ?  325  TYR A CD2  1 
ATOM   4853  C CE1  . TYR A 1 359 ? -6.896  -1.424  23.033 1.00 8.57  ?  325  TYR A CE1  1 
ATOM   4854  C CE2  . TYR A 1 359 ? -4.661  -2.029  23.646 1.00 8.03  ?  325  TYR A CE2  1 
ATOM   4855  C CZ   . TYR A 1 359 ? -5.714  -2.064  22.747 1.00 7.97  ?  325  TYR A CZ   1 
ATOM   4856  O OH   . TYR A 1 359 ? -5.616  -2.747  21.537 1.00 9.13  ?  325  TYR A OH   1 
ATOM   4857  H H    . TYR A 1 359 ? -8.667  -0.736  27.177 1.00 10.81 ?  325  TYR A H    1 
ATOM   4858  H HA   . TYR A 1 359 ? -6.145  -1.419  27.907 1.00 9.32  ?  325  TYR A HA   1 
ATOM   4859  H HB2  . TYR A 1 359 ? -6.716  0.844   26.274 1.00 9.45  ?  325  TYR A HB2  1 
ATOM   4860  H HB3  . TYR A 1 359 ? -5.262  0.379   26.714 1.00 9.45  ?  325  TYR A HB3  1 
ATOM   4861  H HD1  . TYR A 1 359 ? -7.830  -0.287  24.398 1.00 10.46 ?  325  TYR A HD1  1 
ATOM   4862  H HD2  . TYR A 1 359 ? -4.100  -1.285  25.431 1.00 10.55 ?  325  TYR A HD2  1 
ATOM   4863  H HE1  . TYR A 1 359 ? -7.602  -1.458  22.430 1.00 10.28 ?  325  TYR A HE1  1 
ATOM   4864  H HE2  . TYR A 1 359 ? -3.865  -2.472  23.457 1.00 9.64  ?  325  TYR A HE2  1 
ATOM   4865  H HH   . TYR A 1 359 ? -4.818  -2.970  21.397 1.00 10.96 ?  325  TYR A HH   1 
ATOM   4866  N N    . VAL A 1 360 ? -6.013  0.375   29.655 1.00 8.05  ?  326  VAL A N    1 
ATOM   4867  C CA   . VAL A 1 360 ? -6.157  1.179   30.874 1.00 8.44  ?  326  VAL A CA   1 
ATOM   4868  C C    . VAL A 1 360 ? -5.082  2.258   30.984 1.00 7.32  ?  326  VAL A C    1 
ATOM   4869  O O    . VAL A 1 360 ? -3.940  2.086   30.556 1.00 7.89  ?  326  VAL A O    1 
ATOM   4870  C CB   . VAL A 1 360 ? -6.160  0.259   32.125 1.00 8.89  ?  326  VAL A CB   1 
ATOM   4871  C CG1  . VAL A 1 360 ? -4.771  -0.360  32.354 1.00 10.36 ?  326  VAL A CG1  1 
ATOM   4872  C CG2  . VAL A 1 360 ? -6.615  1.003   33.373 1.00 9.56  ?  326  VAL A CG2  1 
ATOM   4873  H H    . VAL A 1 360 ? -5.237  0.016   29.568 1.00 9.66  ?  326  VAL A H    1 
ATOM   4874  H HA   . VAL A 1 360 ? -6.993  1.668   30.817 1.00 10.12 ?  326  VAL A HA   1 
ATOM   4875  H HB   . VAL A 1 360 ? -6.795  -0.456  31.960 1.00 10.67 ?  326  VAL A HB   1 
ATOM   4876  H HG11 . VAL A 1 360 ? -4.853  -1.096  32.980 1.00 12.43 ?  326  VAL A HG11 1 
ATOM   4877  H HG12 . VAL A 1 360 ? -4.425  -0.682  31.507 1.00 12.43 ?  326  VAL A HG12 1 
ATOM   4878  H HG13 . VAL A 1 360 ? -4.180  0.318   32.716 1.00 12.43 ?  326  VAL A HG13 1 
ATOM   4879  H HG21 . VAL A 1 360 ? -6.729  0.366   34.096 1.00 11.47 ?  326  VAL A HG21 1 
ATOM   4880  H HG22 . VAL A 1 360 ? -5.941  1.658   33.613 1.00 11.47 ?  326  VAL A HG22 1 
ATOM   4881  H HG23 . VAL A 1 360 ? -7.457  1.447   33.187 1.00 11.47 ?  326  VAL A HG23 1 
ATOM   4882  N N    . TYR A 1 361 ? -5.465  3.393   31.576 1.00 8.48  ?  327  TYR A N    1 
ATOM   4883  C CA   . TYR A 1 361 ? -4.523  4.457   31.942 1.00 8.61  ?  327  TYR A CA   1 
ATOM   4884  C C    . TYR A 1 361 ? -4.864  4.960   33.334 1.00 10.00 ?  327  TYR A C    1 
ATOM   4885  O O    . TYR A 1 361 ? -5.917  5.567   33.535 1.00 9.09  ?  327  TYR A O    1 
ATOM   4886  C CB   . TYR A 1 361 ? -4.568  5.607   30.941 1.00 7.90  ?  327  TYR A CB   1 
ATOM   4887  C CG   . TYR A 1 361 ? -3.531  6.710   31.129 1.00 9.81  ?  327  TYR A CG   1 
ATOM   4888  C CD1  . TYR A 1 361 ? -2.397  6.511   31.893 1.00 9.50  ?  327  TYR A CD1  1 
ATOM   4889  C CD2  . TYR A 1 361 ? -3.689  7.937   30.503 1.00 10.03 ?  327  TYR A CD2  1 
ATOM   4890  C CE1  . TYR A 1 361 ? -1.434  7.519   32.040 1.00 9.92  ?  327  TYR A CE1  1 
ATOM   4891  C CE2  . TYR A 1 361 ? -2.739  8.932   30.629 1.00 9.34  ?  327  TYR A CE2  1 
ATOM   4892  C CZ   . TYR A 1 361 ? -1.617  8.724   31.403 1.00 9.74  ?  327  TYR A CZ   1 
ATOM   4893  O OH   . TYR A 1 361 ? -0.657  9.729   31.531 1.00 10.81 ?  327  TYR A OH   1 
ATOM   4894  H H    . TYR A 1 361 ? -6.280  3.574   31.780 1.00 10.17 ?  327  TYR A H    1 
ATOM   4895  H HA   . TYR A 1 361 ? -3.627  4.084   31.961 1.00 10.34 ?  327  TYR A HA   1 
ATOM   4896  H HB2  . TYR A 1 361 ? -4.435  5.240   30.053 1.00 9.48  ?  327  TYR A HB2  1 
ATOM   4897  H HB3  . TYR A 1 361 ? -5.442  6.025   31.000 1.00 9.48  ?  327  TYR A HB3  1 
ATOM   4898  H HD1  . TYR A 1 361 ? -2.271  5.693   32.317 1.00 11.40 ?  327  TYR A HD1  1 
ATOM   4899  H HD2  . TYR A 1 361 ? -4.449  8.094   29.990 1.00 12.03 ?  327  TYR A HD2  1 
ATOM   4900  H HE1  . TYR A 1 361 ? -0.680  7.374   32.564 1.00 11.90 ?  327  TYR A HE1  1 
ATOM   4901  H HE2  . TYR A 1 361 ? -2.855  9.743   30.189 1.00 11.21 ?  327  TYR A HE2  1 
ATOM   4902  H HH   . TYR A 1 361 ? -0.882  10.401  31.081 1.00 12.97 ?  327  TYR A HH   1 
ATOM   4903  N N    . LEU A 1 362 ? -3.964  4.714   34.283 1.00 9.42  ?  328  LEU A N    1 
ATOM   4904  C CA   . LEU A 1 362 ? -4.032  5.297   35.624 1.00 9.24  ?  328  LEU A CA   1 
ATOM   4905  C C    . LEU A 1 362 ? -3.181  6.559   35.606 1.00 8.76  ?  328  LEU A C    1 
ATOM   4906  O O    . LEU A 1 362 ? -1.963  6.496   35.421 1.00 10.48 ?  328  LEU A O    1 
ATOM   4907  C CB   . LEU A 1 362 ? -3.510  4.316   36.669 1.00 10.08 ?  328  LEU A CB   1 
ATOM   4908  C CG   . LEU A 1 362 ? -4.093  2.907   36.640 1.00 11.57 ?  328  LEU A CG   1 
ATOM   4909  C CD1  . LEU A 1 362 ? -3.485  2.115   37.826 1.00 13.97 ?  328  LEU A CD1  1 
ATOM   4910  C CD2  . LEU A 1 362 ? -5.602  2.894   36.692 1.00 11.86 ?  328  LEU A CD2  1 
ATOM   4911  H H    . LEU A 1 362 ? -3.285  4.198   34.173 1.00 11.30 ?  328  LEU A H    1 
ATOM   4912  H HA   . LEU A 1 362 ? -4.950  5.516   35.848 1.00 11.08 ?  328  LEU A HA   1 
ATOM   4913  H HB2  . LEU A 1 362 ? -2.551  4.229   36.545 1.00 12.09 ?  328  LEU A HB2  1 
ATOM   4914  H HB3  . LEU A 1 362 ? -3.699  4.683   37.546 1.00 12.09 ?  328  LEU A HB3  1 
ATOM   4915  H HG   . LEU A 1 362 ? -3.866  2.482   35.798 1.00 13.88 ?  328  LEU A HG   1 
ATOM   4916  H HD11 . LEU A 1 362 ? -3.933  1.258   37.896 1.00 16.76 ?  328  LEU A HD11 1 
ATOM   4917  H HD12 . LEU A 1 362 ? -2.538  1.981   37.665 1.00 16.76 ?  328  LEU A HD12 1 
ATOM   4918  H HD13 . LEU A 1 362 ? -3.613  2.623   38.643 1.00 16.76 ?  328  LEU A HD13 1 
ATOM   4919  H HD21 . LEU A 1 362 ? -5.911  1.975   36.646 1.00 14.23 ?  328  LEU A HD21 1 
ATOM   4920  H HD22 . LEU A 1 362 ? -5.892  3.299   37.524 1.00 14.23 ?  328  LEU A HD22 1 
ATOM   4921  H HD23 . LEU A 1 362 ? -5.948  3.398   35.939 1.00 14.23 ?  328  LEU A HD23 1 
ATOM   4922  N N    . HIS A 1 363 ? -3.828  7.716   35.738 1.00 8.52  ?  329  HIS A N    1 
ATOM   4923  C CA   . HIS A 1 363 ? -3.154  8.956   35.390 1.00 8.53  ?  329  HIS A CA   1 
ATOM   4924  C C    . HIS A 1 363 ? -3.114  9.957   36.531 1.00 8.66  ?  329  HIS A C    1 
ATOM   4925  O O    . HIS A 1 363 ? -3.867  9.871   37.501 1.00 9.46  ?  329  HIS A O    1 
ATOM   4926  C CB   . HIS A 1 363 ? -3.857  9.615   34.195 1.00 10.02 ?  329  HIS A CB   1 
ATOM   4927  C CG   . HIS A 1 363 ? -5.254  10.061  34.492 1.00 9.92  ?  329  HIS A CG   1 
ATOM   4928  N ND1  . HIS A 1 363 ? -5.546  11.267  35.097 1.00 9.71  ?  329  HIS A ND1  1 
ATOM   4929  C CD2  . HIS A 1 363 ? -6.446  9.460   34.255 1.00 9.22  ?  329  HIS A CD2  1 
ATOM   4930  C CE1  . HIS A 1 363 ? -6.857  11.390  35.208 1.00 10.44 ?  329  HIS A CE1  1 
ATOM   4931  N NE2  . HIS A 1 363 ? -7.424  10.310  34.701 1.00 10.60 ?  329  HIS A NE2  1 
ATOM   4932  H H    . HIS A 1 363 ? -4.636  7.801   36.021 1.00 10.23 ?  329  HIS A H    1 
ATOM   4933  H HA   . HIS A 1 363 ? -2.232  8.738   35.181 1.00 10.23 ?  329  HIS A HA   1 
ATOM   4934  H HB2  . HIS A 1 363 ? -3.349  10.396  33.925 1.00 12.03 ?  329  HIS A HB2  1 
ATOM   4935  H HB3  . HIS A 1 363 ? -3.899  8.977   33.466 1.00 12.03 ?  329  HIS A HB3  1 
ATOM   4936  H HD2  . HIS A 1 363 ? -6.576  8.626   33.864 1.00 11.07 ?  329  HIS A HD2  1 
ATOM   4937  H HE1  . HIS A 1 363 ? -7.305  12.115  35.581 1.00 12.53 ?  329  HIS A HE1  1 
ATOM   4938  H HE2  . HIS A 1 363 ? -8.271  10.165  34.657 1.00 12.72 ?  329  HIS A HE2  1 
ATOM   4939  N N    . ASP A 1 364 ? -2.244  10.947  36.339 1.00 8.78  ?  330  ASP A N    1 
ATOM   4940  C CA   . ASP A 1 364 ? -2.197  12.157  37.158 1.00 8.98  ?  330  ASP A CA   1 
ATOM   4941  C C    . ASP A 1 364 ? -2.368  13.356  36.237 1.00 9.18  ?  330  ASP A C    1 
ATOM   4942  O O    . ASP A 1 364 ? -1.509  14.239  36.191 1.00 9.05  ?  330  ASP A O    1 
ATOM   4943  C CB   . ASP A 1 364 ? -0.870  12.213  37.920 1.00 9.74  ?  330  ASP A CB   1 
ATOM   4944  C CG   . ASP A 1 364 ? -0.762  13.404  38.874 1.00 9.10  ?  330  ASP A CG   1 
ATOM   4945  O OD1  . ASP A 1 364 ? -1.803  13.894  39.328 1.00 11.40 ?  330  ASP A OD1  1 
ATOM   4946  O OD2  . ASP A 1 364 ? 0.392   13.819  39.149 1.00 10.25 ?  330  ASP A OD2  1 
ATOM   4947  H H    . ASP A 1 364 ? -1.648  10.942  35.719 1.00 10.54 ?  330  ASP A H    1 
ATOM   4948  H HA   . ASP A 1 364 ? -2.903  12.171  37.823 1.00 10.78 ?  330  ASP A HA   1 
ATOM   4949  H HB2  . ASP A 1 364 ? -0.777  11.403  38.446 1.00 11.68 ?  330  ASP A HB2  1 
ATOM   4950  H HB3  . ASP A 1 364 ? -0.144  12.279  37.280 1.00 11.68 ?  330  ASP A HB3  1 
ATOM   4951  N N    . GLY A 1 365 ? -3.465  13.366  35.490 1.00 9.31  ?  331  GLY A N    1 
ATOM   4952  C CA   . GLY A 1 365 ? -3.759  14.397  34.519 1.00 8.66  ?  331  GLY A CA   1 
ATOM   4953  C C    . GLY A 1 365 ? -3.115  14.100  33.179 1.00 9.10  ?  331  GLY A C    1 
ATOM   4954  O O    . GLY A 1 365 ? -2.176  13.313  33.068 1.00 10.07 ?  331  GLY A O    1 
ATOM   4955  H H    . GLY A 1 365 ? -4.075  12.762  35.532 1.00 11.17 ?  331  GLY A H    1 
ATOM   4956  H HA2  . GLY A 1 365 ? -4.718  14.461  34.394 1.00 10.39 ?  331  GLY A HA2  1 
ATOM   4957  H HA3  . GLY A 1 365 ? -3.425  15.249  34.841 1.00 10.39 ?  331  GLY A HA3  1 
ATOM   4958  N N    . TYR A 1 366 ? -3.615  14.763  32.137 1.00 7.87  ?  332  TYR A N    1 
ATOM   4959  C CA   . TYR A 1 366 ? -3.146  14.464  30.791 1.00 8.17  ?  332  TYR A CA   1 
ATOM   4960  C C    . TYR A 1 366 ? -1.992  15.348  30.331 1.00 9.05  ?  332  TYR A C    1 
ATOM   4961  O O    . TYR A 1 366 ? -1.325  14.996  29.353 1.00 11.99 ?  332  TYR A O    1 
ATOM   4962  C CB   . TYR A 1 366 ? -4.328  14.519  29.825 1.00 8.38  ?  332  TYR A CB   1 
ATOM   4963  C CG   . TYR A 1 366 ? -5.421  13.510  30.172 1.00 7.54  ?  332  TYR A CG   1 
ATOM   4964  C CD1  . TYR A 1 366 ? -5.106  12.234  30.653 1.00 8.34  ?  332  TYR A CD1  1 
ATOM   4965  C CD2  . TYR A 1 366 ? -6.746  13.826  30.040 1.00 8.07  ?  332  TYR A CD2  1 
ATOM   4966  C CE1  . TYR A 1 366 ? -6.086  11.314  30.973 1.00 8.19  ?  332  TYR A CE1  1 
ATOM   4967  C CE2  . TYR A 1 366 ? -7.745  12.890  30.358 1.00 8.26  ?  332  TYR A CE2  1 
ATOM   4968  C CZ   . TYR A 1 366 ? -7.397  11.639  30.816 1.00 7.90  ?  332  TYR A CZ   1 
ATOM   4969  O OH   . TYR A 1 366 ? -8.339  10.702  31.170 1.00 9.19  ?  332  TYR A OH   1 
ATOM   4970  H H    . TYR A 1 366 ? -4.215  15.377  32.186 1.00 9.45  ?  332  TYR A H    1 
ATOM   4971  H HA   . TYR A 1 366 ? -2.797  13.560  30.759 1.00 9.81  ?  332  TYR A HA   1 
ATOM   4972  H HB2  . TYR A 1 366 ? -4.719  15.406  29.853 1.00 10.06 ?  332  TYR A HB2  1 
ATOM   4973  H HB3  . TYR A 1 366 ? -4.013  14.324  28.928 1.00 10.06 ?  332  TYR A HB3  1 
ATOM   4974  H HD1  . TYR A 1 366 ? -4.213  11.998  30.761 1.00 10.01 ?  332  TYR A HD1  1 
ATOM   4975  H HD2  . TYR A 1 366 ? -6.988  14.670  29.736 1.00 9.69  ?  332  TYR A HD2  1 
ATOM   4976  H HE1  . TYR A 1 366 ? -5.849  10.474  31.295 1.00 9.83  ?  332  TYR A HE1  1 
ATOM   4977  H HE2  . TYR A 1 366 ? -8.642  13.115  30.258 1.00 9.91  ?  332  TYR A HE2  1 
ATOM   4978  H HH   . TYR A 1 366 ? -9.080  10.896  30.827 1.00 11.02 ?  332  TYR A HH   1 
ATOM   4979  N N    . LEU A 1 367 ? -1.674  16.410  31.058 1.00 8.40  ?  333  LEU A N    1 
ATOM   4980  C CA   . LEU A 1 367 ? -0.509  17.229  30.743 1.00 8.51  ?  333  LEU A CA   1 
ATOM   4981  C C    . LEU A 1 367 ? 0.758   16.538  31.248 1.00 7.22  ?  333  LEU A C    1 
ATOM   4982  O O    . LEU A 1 367 ? 0.951   16.365  32.461 1.00 8.68  ?  333  LEU A O    1 
ATOM   4983  C CB   . LEU A 1 367 ? -0.645  18.610  31.374 1.00 8.07  ?  333  LEU A CB   1 
ATOM   4984  C CG   . LEU A 1 367 ? 0.555   19.538  31.165 1.00 7.81  ?  333  LEU A CG   1 
ATOM   4985  C CD1  . LEU A 1 367 ? 0.895   19.753  29.709 1.00 8.63  ?  333  LEU A CD1  1 
ATOM   4986  C CD2  . LEU A 1 367 ? 0.276   20.864  31.858 1.00 9.12  ?  333  LEU A CD2  1 
ATOM   4987  H H    . LEU A 1 367 ? -2.118  16.680  31.743 1.00 10.08 ?  333  LEU A H    1 
ATOM   4988  H HA   . LEU A 1 367 ? -0.443  17.334  29.781 1.00 10.21 ?  333  LEU A HA   1 
ATOM   4989  H HB2  . LEU A 1 367 ? -1.421  19.047  30.990 1.00 9.69  ?  333  LEU A HB2  1 
ATOM   4990  H HB3  . LEU A 1 367 ? -0.765  18.499  32.330 1.00 9.69  ?  333  LEU A HB3  1 
ATOM   4991  H HG   . LEU A 1 367 ? 1.339   19.119  31.553 1.00 9.37  ?  333  LEU A HG   1 
ATOM   4992  H HD11 . LEU A 1 367 ? 1.639   20.373  29.646 1.00 10.35 ?  333  LEU A HD11 1 
ATOM   4993  H HD12 . LEU A 1 367 ? 1.139   18.902  29.313 1.00 10.35 ?  333  LEU A HD12 1 
ATOM   4994  H HD13 . LEU A 1 367 ? 0.121   20.120  29.254 1.00 10.35 ?  333  LEU A HD13 1 
ATOM   4995  H HD21 . LEU A 1 367 ? 1.061   21.429  31.787 1.00 10.94 ?  333  LEU A HD21 1 
ATOM   4996  H HD22 . LEU A 1 367 ? -0.480  21.293  31.426 1.00 10.94 ?  333  LEU A HD22 1 
ATOM   4997  H HD23 . LEU A 1 367 ? 0.072   20.696  32.791 1.00 10.94 ?  333  LEU A HD23 1 
ATOM   4998  N N    . ALA A 1 368 ? 1.645   16.176  30.325 1.00 7.07  ?  334  ALA A N    1 
ATOM   4999  C CA   . ALA A 1 368 ? 2.800   15.354  30.672 1.00 8.08  ?  334  ALA A CA   1 
ATOM   5000  C C    . ALA A 1 368 ? 3.661   16.002  31.738 1.00 9.10  ?  334  ALA A C    1 
ATOM   5001  O O    . ALA A 1 368 ? 4.147   15.320  32.648 1.00 10.18 ?  334  ALA A O    1 
ATOM   5002  C CB   . ALA A 1 368 ? 3.641   15.102  29.421 1.00 10.70 ?  334  ALA A CB   1 
ATOM   5003  H H    . ALA A 1 368 ? 1.602   16.392  29.493 1.00 8.48  ?  334  ALA A H    1 
ATOM   5004  H HA   . ALA A 1 368 ? 2.476   14.509  31.020 1.00 9.70  ?  334  ALA A HA   1 
ATOM   5005  H HB1  . ALA A 1 368 ? 4.415   14.568  29.663 1.00 12.84 ?  334  ALA A HB1  1 
ATOM   5006  H HB2  . ALA A 1 368 ? 3.103   14.626  28.768 1.00 12.84 ?  334  ALA A HB2  1 
ATOM   5007  H HB3  . ALA A 1 368 ? 3.928   15.953  29.055 1.00 12.84 ?  334  ALA A HB3  1 
ATOM   5008  N N    . THR A 1 369 ? 3.881   17.311  31.637 1.00 8.02  ?  335  THR A N    1 
ATOM   5009  C CA   . THR A 1 369 ? 4.836   18.014  32.481 1.00 8.01  ?  335  THR A CA   1 
ATOM   5010  C C    . THR A 1 369 ? 4.318   18.256  33.888 1.00 9.36  ?  335  THR A C    1 
ATOM   5011  O O    . THR A 1 369 ? 5.079   18.736  34.742 1.00 10.23 ?  335  THR A O    1 
ATOM   5012  C CB   . THR A 1 369 ? 5.220   19.336  31.821 1.00 8.05  ?  335  THR A CB   1 
ATOM   5013  O OG1  . THR A 1 369 ? 4.044   20.012  31.351 1.00 8.34  ?  335  THR A OG1  1 
ATOM   5014  C CG2  . THR A 1 369 ? 6.169   19.117  30.642 1.00 10.50 ?  335  THR A CG2  1 
ATOM   5015  H H    . THR A 1 369 ? 3.479   17.823  31.075 1.00 9.62  ?  335  THR A H    1 
ATOM   5016  H HA   . THR A 1 369 ? 5.642   17.481  32.566 1.00 9.61  ?  335  THR A HA   1 
ATOM   5017  H HB   . THR A 1 369 ? 5.674   19.886  32.479 1.00 9.66  ?  335  THR A HB   1 
ATOM   5018  H HG1  . THR A 1 369 ? 3.711   20.473  31.970 1.00 10.01 ?  335  THR A HG1  1 
ATOM   5019  H HG21 . THR A 1 369 ? 6.514   19.969  30.331 1.00 12.60 ?  335  THR A HG21 1 
ATOM   5020  H HG22 . THR A 1 369 ? 6.913   18.558  30.914 1.00 12.60 ?  335  THR A HG22 1 
ATOM   5021  H HG23 . THR A 1 369 ? 5.699   18.683  29.913 1.00 12.60 ?  335  THR A HG23 1 
ATOM   5022  N N    . ASN A 1 370 ? 3.060   17.931  34.167 1.00 8.72  ?  336  ASN A N    1 
ATOM   5023  C CA   . ASN A 1 370 ? 2.501   18.086  35.500 1.00 8.90  ?  336  ASN A CA   1 
ATOM   5024  C C    . ASN A 1 370 ? 2.018   16.765  36.081 1.00 10.20 ?  336  ASN A C    1 
ATOM   5025  O O    . ASN A 1 370 ? 1.295   16.761  37.081 1.00 11.30 ?  336  ASN A O    1 
ATOM   5026  C CB   . ASN A 1 370 ? 1.380   19.134  35.504 1.00 11.09 ?  336  ASN A CB   1 
ATOM   5027  C CG   . ASN A 1 370 ? 1.085   19.667  36.894 1.00 11.53 ?  336  ASN A CG   1 
ATOM   5028  O OD1  . ASN A 1 370 ? 1.991   19.948  37.651 1.00 14.21 ?  336  ASN A OD1  1 
ATOM   5029  N ND2  . ASN A 1 370 ? -0.189  19.820  37.210 1.00 14.68 ?  336  ASN A ND2  1 
ATOM   5030  H H    . ASN A 1 370 ? 2.505   17.614  33.592 1.00 10.46 ?  336  ASN A H    1 
ATOM   5031  H HA   . ASN A 1 370 ? 3.195   18.421  36.090 1.00 10.68 ?  336  ASN A HA   1 
ATOM   5032  H HB2  . ASN A 1 370 ? 1.643   19.881  34.945 1.00 13.31 ?  336  ASN A HB2  1 
ATOM   5033  H HB3  . ASN A 1 370 ? 0.568   18.730  35.158 1.00 13.31 ?  336  ASN A HB3  1 
ATOM   5034  H HD21 . ASN A 1 370 ? -0.406  20.119  37.987 1.00 17.62 ?  336  ASN A HD21 1 
ATOM   5035  H HD22 . ASN A 1 370 ? -0.801  19.620  36.640 1.00 17.62 ?  336  ASN A HD22 1 
ATOM   5036  N N    . SER A 1 371 ? 2.396   15.638  35.489 1.00 9.30  ?  337  SER A N    1 
ATOM   5037  C CA   . SER A 1 371 ? 1.974   14.326  35.953 1.00 9.36  ?  337  SER A CA   1 
ATOM   5038  C C    . SER A 1 371 ? 3.106   13.616  36.680 1.00 9.84  ?  337  SER A C    1 
ATOM   5039  O O    . SER A 1 371 ? 4.194   13.433  36.122 1.00 10.74 ?  337  SER A O    1 
ATOM   5040  C CB   . SER A 1 371 ? 1.522   13.468  34.770 1.00 10.24 ?  337  SER A CB   1 
ATOM   5041  O OG   . SER A 1 371 ? 1.453   12.119  35.190 1.00 9.43  ?  337  SER A OG   1 
ATOM   5042  H H    . SER A 1 371 ? 2.910   15.608  34.799 1.00 11.16 ?  337  SER A H    1 
ATOM   5043  H HA   . SER A 1 371 ? 1.242   14.440  36.579 1.00 11.23 ?  337  SER A HA   1 
ATOM   5044  H HB2  . SER A 1 371 ? 0.647   13.761  34.472 1.00 12.29 ?  337  SER A HB2  1 
ATOM   5045  H HB3  . SER A 1 371 ? 2.163   13.550  34.046 1.00 12.29 ?  337  SER A HB3  1 
ATOM   5046  H HG   . SER A 1 371 ? 1.154   11.639  34.569 1.00 11.32 ?  337  SER A HG   1 
ATOM   5047  N N    . ALA A 1 372 ? 2.812   13.144  37.892 1.00 11.14 ?  338  ALA A N    1 
ATOM   5048  C CA   . ALA A 1 372 ? 3.806   12.414  38.667 1.00 11.91 ?  338  ALA A CA   1 
ATOM   5049  C C    . ALA A 1 372 ? 4.063   11.018  38.129 1.00 13.49 ?  338  ALA A C    1 
ATOM   5050  O O    . ALA A 1 372 ? 5.046   10.390  38.546 1.00 13.41 ?  338  ALA A O    1 
ATOM   5051  C CB   . ALA A 1 372 ? 3.352   12.301  40.119 1.00 15.25 ?  338  ALA A CB   1 
ATOM   5052  H H    . ALA A 1 372 ? 2.051   13.235  38.281 1.00 13.37 ?  338  ALA A H    1 
ATOM   5053  H HA   . ALA A 1 372 ? 4.638   12.911  38.639 1.00 14.29 ?  338  ALA A HA   1 
ATOM   5054  H HB1  . ALA A 1 372 ? 4.009   11.791  40.617 1.00 18.30 ?  338  ALA A HB1  1 
ATOM   5055  H HB2  . ALA A 1 372 ? 3.270   13.191  40.495 1.00 18.30 ?  338  ALA A HB2  1 
ATOM   5056  H HB3  . ALA A 1 372 ? 2.493   11.850  40.148 1.00 18.30 ?  338  ALA A HB3  1 
ATOM   5057  N N    . VAL A 1 373 ? 3.196   10.495  37.254 1.00 11.22 ?  339  VAL A N    1 
ATOM   5058  C CA   . VAL A 1 373 ? 3.391   9.167   36.682 1.00 11.48 ?  339  VAL A CA   1 
ATOM   5059  C C    . VAL A 1 373 ? 3.937   9.210   35.272 1.00 10.91 ?  339  VAL A C    1 
ATOM   5060  O O    . VAL A 1 373 ? 4.145   8.156   34.659 1.00 12.35 ?  339  VAL A O    1 
ATOM   5061  C CB   . VAL A 1 373 ? 2.129   8.283   36.770 1.00 11.94 ?  339  VAL A CB   1 
ATOM   5062  C CG1  . VAL A 1 373 ? 1.699   8.095   38.220 1.00 12.95 ?  339  VAL A CG1  1 
ATOM   5063  C CG2  . VAL A 1 373 ? 0.962   8.845   35.954 1.00 10.86 ?  339  VAL A CG2  1 
ATOM   5064  H H    . VAL A 1 373 ? 2.486   10.894  36.979 1.00 13.46 ?  339  VAL A H    1 
ATOM   5065  H HA   . VAL A 1 373 ? 4.061   8.725   37.228 1.00 13.78 ?  339  VAL A HA   1 
ATOM   5066  H HB   . VAL A 1 373 ? 2.361   7.422   36.389 1.00 14.33 ?  339  VAL A HB   1 
ATOM   5067  H HG11 . VAL A 1 373 ? 0.912   7.530   38.246 1.00 15.55 ?  339  VAL A HG11 1 
ATOM   5068  H HG12 . VAL A 1 373 ? 2.423   7.677   38.712 1.00 15.55 ?  339  VAL A HG12 1 
ATOM   5069  H HG13 . VAL A 1 373 ? 1.497   8.963   38.604 1.00 15.55 ?  339  VAL A HG13 1 
ATOM   5070  H HG21 . VAL A 1 373 ? 0.244   8.193   35.939 1.00 13.04 ?  339  VAL A HG21 1 
ATOM   5071  H HG22 . VAL A 1 373 ? 0.654   9.667   36.368 1.00 13.04 ?  339  VAL A HG22 1 
ATOM   5072  H HG23 . VAL A 1 373 ? 1.265   9.024   35.050 1.00 13.04 ?  339  VAL A HG23 1 
ATOM   5073  N N    . TRP A 1 374 ? 4.197   10.394  34.735 1.00 10.77 ?  340  TRP A N    1 
ATOM   5074  C CA   . TRP A 1 374 ? 4.761   10.480  33.399 1.00 10.75 ?  340  TRP A CA   1 
ATOM   5075  C C    . TRP A 1 374 ? 6.065   9.704   33.336 1.00 12.12 ?  340  TRP A C    1 
ATOM   5076  O O    . TRP A 1 374 ? 6.924   9.841   34.204 1.00 13.39 ?  340  TRP A O    1 
ATOM   5077  C CB   . TRP A 1 374 ? 5.012   11.946  33.076 1.00 12.24 ?  340  TRP A CB   1 
ATOM   5078  C CG   . TRP A 1 374 ? 5.595   12.248  31.733 1.00 10.46 ?  340  TRP A CG   1 
ATOM   5079  C CD1  . TRP A 1 374 ? 6.748   12.928  31.496 1.00 12.10 ?  340  TRP A CD1  1 
ATOM   5080  C CD2  . TRP A 1 374 ? 5.051   11.913  30.450 1.00 9.11  ?  340  TRP A CD2  1 
ATOM   5081  N NE1  . TRP A 1 374 ? 6.958   13.040  30.152 1.00 11.14 ?  340  TRP A NE1  1 
ATOM   5082  C CE2  . TRP A 1 374 ? 5.936   12.424  29.483 1.00 8.87  ?  340  TRP A CE2  1 
ATOM   5083  C CE3  . TRP A 1 374 ? 3.909   11.229  30.021 1.00 11.43 ?  340  TRP A CE3  1 
ATOM   5084  C CZ2  . TRP A 1 374 ? 5.713   12.288  28.121 1.00 9.74  ?  340  TRP A CZ2  1 
ATOM   5085  C CZ3  . TRP A 1 374 ? 3.696   11.086  28.656 1.00 10.94 ?  340  TRP A CZ3  1 
ATOM   5086  C CH2  . TRP A 1 374 ? 4.597   11.612  27.725 1.00 11.24 ?  340  TRP A CH2  1 
ATOM   5087  H H    . TRP A 1 374 ? 4.058   11.151  35.118 1.00 12.92 ?  340  TRP A H    1 
ATOM   5088  H HA   . TRP A 1 374 ? 4.151   10.104  32.745 1.00 12.90 ?  340  TRP A HA   1 
ATOM   5089  H HB2  . TRP A 1 374 ? 4.164   12.414  33.128 1.00 14.68 ?  340  TRP A HB2  1 
ATOM   5090  H HB3  . TRP A 1 374 ? 5.628   12.298  33.738 1.00 14.68 ?  340  TRP A HB3  1 
ATOM   5091  H HD1  . TRP A 1 374 ? 7.312   13.268  32.154 1.00 14.52 ?  340  TRP A HD1  1 
ATOM   5092  H HE1  . TRP A 1 374 ? 7.627   13.435  29.783 1.00 13.37 ?  340  TRP A HE1  1 
ATOM   5093  H HE3  . TRP A 1 374 ? 3.306   10.878  30.636 1.00 13.72 ?  340  TRP A HE3  1 
ATOM   5094  H HZ2  . TRP A 1 374 ? 6.305   12.646  27.499 1.00 11.69 ?  340  TRP A HZ2  1 
ATOM   5095  H HZ3  . TRP A 1 374 ? 2.941   10.633  28.356 1.00 13.13 ?  340  TRP A HZ3  1 
ATOM   5096  H HH2  . TRP A 1 374 ? 4.431   11.499  26.817 1.00 13.48 ?  340  TRP A HH2  1 
ATOM   5097  N N    . LEU A 1 375 ? 6.207   8.885   32.299 1.00 11.11 ?  341  LEU A N    1 
ATOM   5098  C CA   . LEU A 1 375 ? 7.370   8.043   32.022 1.00 13.22 ?  341  LEU A CA   1 
ATOM   5099  C C    . LEU A 1 375 ? 7.474   6.833   32.951 1.00 15.45 ?  341  LEU A C    1 
ATOM   5100  O O    . LEU A 1 375 ? 8.433   6.045   32.815 1.00 17.83 ?  341  LEU A O    1 
ATOM   5101  C CB   . LEU A 1 375 ? 8.695   8.825   32.040 1.00 15.05 ?  341  LEU A CB   1 
ATOM   5102  C CG   . LEU A 1 375 ? 8.791   9.939   31.011 1.00 13.64 ?  341  LEU A CG   1 
ATOM   5103  C CD1  . LEU A 1 375 ? 10.014  10.798  31.182 1.00 19.38 ?  341  LEU A CD1  1 
ATOM   5104  C CD2  . LEU A 1 375 ? 8.776   9.378   29.612 1.00 18.27 ?  341  LEU A CD2  1 
ATOM   5105  H H    . LEU A 1 375 ? 5.597   8.795   31.699 1.00 13.33 ?  341  LEU A H    1 
ATOM   5106  H HA   . LEU A 1 375 ? 7.261   7.694   31.123 1.00 15.87 ?  341  LEU A HA   1 
ATOM   5107  H HB2  . LEU A 1 375 ? 8.802   9.227   32.917 1.00 18.06 ?  341  LEU A HB2  1 
ATOM   5108  H HB3  . LEU A 1 375 ? 9.420   8.205   31.869 1.00 18.06 ?  341  LEU A HB3  1 
ATOM   5109  H HG   . LEU A 1 375 ? 8.017   10.507  31.148 1.00 16.37 ?  341  LEU A HG   1 
ATOM   5110  H HD11 . LEU A 1 375 ? 10.019  11.480  30.492 1.00 23.26 ?  341  LEU A HD11 1 
ATOM   5111  H HD12 . LEU A 1 375 ? 9.988   11.213  32.058 1.00 23.26 ?  341  LEU A HD12 1 
ATOM   5112  H HD13 . LEU A 1 375 ? 10.804  10.242  31.102 1.00 23.26 ?  341  LEU A HD13 1 
ATOM   5113  H HD21 . LEU A 1 375 ? 8.930   10.098  28.981 1.00 21.92 ?  341  LEU A HD21 1 
ATOM   5114  H HD22 . LEU A 1 375 ? 9.477   8.712   29.531 1.00 21.92 ?  341  LEU A HD22 1 
ATOM   5115  H HD23 . LEU A 1 375 ? 7.912   8.971   29.444 1.00 21.92 ?  341  LEU A HD23 1 
ATOM   5116  N N    . HIS A 1 376 ? 6.525   6.614   33.852 1.00 12.04 ?  342  HIS A N    1 
ATOM   5117  C CA   . HIS A 1 376 ? 6.661   5.562   34.848 1.00 13.31 ?  342  HIS A CA   1 
ATOM   5118  C C    . HIS A 1 376 ? 5.902   4.303   34.460 1.00 14.86 ?  342  HIS A C    1 
ATOM   5119  O O    . HIS A 1 376 ? 4.779   4.355   33.953 1.00 17.65 ?  342  HIS A O    1 
ATOM   5120  C CB   . HIS A 1 376 ? 6.190   6.032   36.229 1.00 13.73 ?  342  HIS A CB   1 
ATOM   5121  C CG   . HIS A 1 376 ? 6.367   5.008   37.301 1.00 16.14 ?  342  HIS A CG   1 
ATOM   5122  N ND1  . HIS A 1 376 ? 7.607   4.687   37.807 1.00 20.50 ?  342  HIS A ND1  1 
ATOM   5123  C CD2  . HIS A 1 376 ? 5.471   4.276   38.003 1.00 16.08 ?  342  HIS A CD2  1 
ATOM   5124  C CE1  . HIS A 1 376 ? 7.472   3.761   38.740 1.00 17.72 ?  342  HIS A CE1  1 
ATOM   5125  N NE2  . HIS A 1 376 ? 6.184   3.502   38.885 1.00 18.73 ?  342  HIS A NE2  1 
ATOM   5126  H H    . HIS A 1 376 ? 5.793   7.062   33.905 1.00 14.45 ?  342  HIS A H    1 
ATOM   5127  H HA   . HIS A 1 376 ? 7.602   5.331   34.897 1.00 15.97 ?  342  HIS A HA   1 
ATOM   5128  H HB2  . HIS A 1 376 ? 6.699   6.818   36.482 1.00 16.47 ?  342  HIS A HB2  1 
ATOM   5129  H HB3  . HIS A 1 376 ? 5.246   6.250   36.180 1.00 16.47 ?  342  HIS A HB3  1 
ATOM   5130  H HD1  . HIS A 1 376 ? 8.352   5.035   37.556 1.00 24.60 ?  342  HIS A HD1  1 
ATOM   5131  H HD2  . HIS A 1 376 ? 4.546   4.295   37.906 1.00 19.29 ?  342  HIS A HD2  1 
ATOM   5132  H HE1  . HIS A 1 376 ? 8.164   3.360   39.214 1.00 21.26 ?  342  HIS A HE1  1 
ATOM   5133  N N    . GLN A 1 377 ? 6.499   3.161   34.749 1.00 15.62 ?  343  GLN A N    1 
ATOM   5134  C CA   . GLN A 1 377 ? 5.821   1.882   34.583 1.00 18.17 ?  343  GLN A CA   1 
ATOM   5135  C C    . GLN A 1 377 ? 5.722   1.229   35.959 1.00 15.87 ?  343  GLN A C    1 
ATOM   5136  O O    . GLN A 1 377 ? 6.740   0.900   36.577 1.00 16.51 ?  343  GLN A O    1 
ATOM   5137  C CB   . GLN A 1 377 ? 6.519   1.020   33.524 1.00 23.09 ?  343  GLN A CB   1 
ATOM   5138  C CG   . GLN A 1 377 ? 6.406   1.604   32.040 1.00 32.79 ?  343  GLN A CG   1 
ATOM   5139  C CD   . GLN A 1 377 ? 5.242   1.038   31.144 1.00 42.12 ?  343  GLN A CD   1 
ATOM   5140  O OE1  . GLN A 1 377 ? 4.677   1.754   30.253 1.00 19.73 ?  343  GLN A OE1  1 
ATOM   5141  N NE2  . GLN A 1 377 ? 4.900   -0.243  31.362 1.00 33.20 ?  343  GLN A NE2  1 
ATOM   5142  H H    . GLN A 1 377 ? 7.304   3.098   35.045 1.00 18.74 ?  343  GLN A H    1 
ATOM   5143  H HA   . GLN A 1 377 ? 4.913   2.006   34.267 1.00 21.80 ?  343  GLN A HA   1 
ATOM   5144  H HB2  . GLN A 1 377 ? 7.461   0.957   33.746 1.00 27.71 ?  343  GLN A HB2  1 
ATOM   5145  H HB3  . GLN A 1 377 ? 6.117   0.137   33.527 1.00 27.71 ?  343  GLN A HB3  1 
ATOM   5146  H HG2  . GLN A 1 377 ? 6.274   2.563   32.104 1.00 39.34 ?  343  GLN A HG2  1 
ATOM   5147  H HG3  . GLN A 1 377 ? 7.237   1.413   31.578 1.00 39.34 ?  343  GLN A HG3  1 
ATOM   5148  H HE21 . GLN A 1 377 ? 5.312   -0.702  31.962 1.00 39.85 ?  343  GLN A HE21 1 
ATOM   5149  H HE22 . GLN A 1 377 ? 4.271   -0.604  30.901 1.00 39.85 ?  343  GLN A HE22 1 
ATOM   5150  N N    . PHE A 1 378 ? 4.496   1.112   36.461 1.00 14.54 ?  344  PHE A N    1 
ATOM   5151  C CA   . PHE A 1 378 ? 4.252   0.397   37.704 1.00 13.70 ?  344  PHE A CA   1 
ATOM   5152  C C    . PHE A 1 378 ? 4.604   -1.077  37.535 1.00 15.16 ?  344  PHE A C    1 
ATOM   5153  O O    . PHE A 1 378 ? 4.562   -1.632  36.432 1.00 13.55 ?  344  PHE A O    1 
ATOM   5154  C CB   . PHE A 1 378 ? 2.790   0.541   38.111 1.00 14.90 ?  344  PHE A CB   1 
ATOM   5155  C CG   . PHE A 1 378 ? 2.452   1.909   38.638 1.00 16.51 ?  344  PHE A CG   1 
ATOM   5156  C CD1  . PHE A 1 378 ? 2.826   2.275   39.910 1.00 16.64 ?  344  PHE A CD1  1 
ATOM   5157  C CD2  . PHE A 1 378 ? 1.791   2.829   37.848 1.00 18.58 ?  344  PHE A CD2  1 
ATOM   5158  C CE1  . PHE A 1 378 ? 2.533   3.540   40.402 1.00 18.83 ?  344  PHE A CE1  1 
ATOM   5159  C CE2  . PHE A 1 378 ? 1.485   4.095   38.340 1.00 22.10 ?  344  PHE A CE2  1 
ATOM   5160  C CZ   . PHE A 1 378 ? 1.863   4.443   39.616 1.00 18.75 ?  344  PHE A CZ   1 
ATOM   5161  H H    . PHE A 1 378 ? 3.788   1.439   36.099 1.00 17.45 ?  344  PHE A H    1 
ATOM   5162  H HA   . PHE A 1 378 ? 4.802   0.767   38.413 1.00 16.43 ?  344  PHE A HA   1 
ATOM   5163  H HB2  . PHE A 1 378 ? 2.231   0.374   37.336 1.00 17.88 ?  344  PHE A HB2  1 
ATOM   5164  H HB3  . PHE A 1 378 ? 2.593   -0.104  38.808 1.00 17.88 ?  344  PHE A HB3  1 
ATOM   5165  H HD1  . PHE A 1 378 ? 3.282   1.668   40.448 1.00 19.97 ?  344  PHE A HD1  1 
ATOM   5166  H HD2  . PHE A 1 378 ? 1.548   2.600   36.980 1.00 22.30 ?  344  PHE A HD2  1 
ATOM   5167  H HE1  . PHE A 1 378 ? 2.790   3.776   41.264 1.00 22.60 ?  344  PHE A HE1  1 
ATOM   5168  H HE2  . PHE A 1 378 ? 1.026   4.703   37.807 1.00 26.52 ?  344  PHE A HE2  1 
ATOM   5169  H HZ   . PHE A 1 378 ? 1.664   5.290   39.945 1.00 22.50 ?  344  PHE A HZ   1 
ATOM   5170  N N    . ASP A 1 379 ? 4.971   -1.713  38.649 1.00 15.33 ?  345  ASP A N    1 
ATOM   5171  C CA   . ASP A 1 379 ? 5.355   -3.121  38.566 1.00 15.93 ?  345  ASP A CA   1 
ATOM   5172  C C    . ASP A 1 379 ? 4.200   -3.957  38.040 1.00 13.96 ?  345  ASP A C    1 
ATOM   5173  O O    . ASP A 1 379 ? 4.419   -4.963  37.352 1.00 14.80 ?  345  ASP A O    1 
ATOM   5174  C CB   . ASP A 1 379 ? 5.805   -3.640  39.933 1.00 19.10 ?  345  ASP A CB   1 
ATOM   5175  C CG   . ASP A 1 379 ? 7.143   -3.052  40.373 1.00 27.37 ?  345  ASP A CG   1 
ATOM   5176  O OD1  . ASP A 1 379 ? 7.877   -2.504  39.529 1.00 27.18 ?  345  ASP A OD1  1 
ATOM   5177  O OD2  . ASP A 1 379 ? 7.459   -3.154  41.574 1.00 34.26 ?  345  ASP A OD2  1 
ATOM   5178  H H    . ASP A 1 379 ? 5.006   -1.365  39.435 1.00 18.39 ?  345  ASP A H    1 
ATOM   5179  H HA   . ASP A 1 379 ? 6.109   -3.209  37.962 1.00 19.12 ?  345  ASP A HA   1 
ATOM   5180  H HB2  . ASP A 1 379 ? 5.139   -3.403  40.597 1.00 22.92 ?  345  ASP A HB2  1 
ATOM   5181  H HB3  . ASP A 1 379 ? 5.901   -4.605  39.889 1.00 22.92 ?  345  ASP A HB3  1 
ATOM   5182  N N    . GLN A 1 380 ? 2.968   -3.548  38.352 1.00 13.20 ?  346  GLN A N    1 
ATOM   5183  C CA   . GLN A 1 380 ? 1.769   -4.258  37.925 1.00 13.90 ?  346  GLN A CA   1 
ATOM   5184  C C    . GLN A 1 380 ? 1.624   -4.256  36.412 1.00 14.23 ?  346  GLN A C    1 
ATOM   5185  O O    . GLN A 1 380 ? 0.829   -5.038  35.875 1.00 15.93 ?  346  GLN A O    1 
ATOM   5186  C CB   . GLN A 1 380 ? 0.529   -3.580  38.537 1.00 13.39 ?  346  GLN A CB   1 
ATOM   5187  C CG   . GLN A 1 380 ? 0.405   -3.660  40.066 1.00 12.20 ?  346  GLN A CG   1 
ATOM   5188  C CD   . GLN A 1 380 ? 1.108   -2.518  40.797 1.00 12.53 ?  346  GLN A CD   1 
ATOM   5189  O OE1  . GLN A 1 380 ? 2.064   -1.935  40.289 1.00 13.76 ?  346  GLN A OE1  1 
ATOM   5190  N NE2  . GLN A 1 380 ? 0.652   -2.227  42.011 1.00 14.78 ?  346  GLN A NE2  1 
ATOM   5191  H H    . GLN A 1 380 ? 2.798   -2.846  38.820 1.00 15.84 ?  346  GLN A H    1 
ATOM   5192  H HA   . GLN A 1 380 ? 1.819   -5.176  38.235 1.00 16.68 ?  346  GLN A HA   1 
ATOM   5193  H HB2  . GLN A 1 380 ? 0.550   -2.639  38.300 1.00 16.06 ?  346  GLN A HB2  1 
ATOM   5194  H HB3  . GLN A 1 380 ? -0.261  -3.999  38.163 1.00 16.06 ?  346  GLN A HB3  1 
ATOM   5195  H HG2  . GLN A 1 380 ? -0.534  -3.631  40.305 1.00 14.64 ?  346  GLN A HG2  1 
ATOM   5196  H HG3  . GLN A 1 380 ? 0.799   -4.493  40.369 1.00 14.64 ?  346  GLN A HG3  1 
ATOM   5197  H HE21 . GLN A 1 380 ? -0.004  -2.673  42.343 1.00 17.73 ?  346  GLN A HE21 1 
ATOM   5198  H HE22 . GLN A 1 380 ? 1.013   -1.592  42.466 1.00 17.73 ?  346  GLN A HE22 1 
ATOM   5199  N N    . TYR A 1 381 ? 2.339   -3.373  35.713 1.00 12.65 ?  347  TYR A N    1 
ATOM   5200  C CA   . TYR A 1 381 ? 2.287   -3.339  34.263 1.00 11.94 ?  347  TYR A CA   1 
ATOM   5201  C C    . TYR A 1 381 ? 3.288   -4.294  33.626 1.00 13.52 ?  347  TYR A C    1 
ATOM   5202  O O    . TYR A 1 381 ? 3.201   -4.547  32.424 1.00 14.33 ?  347  TYR A O    1 
ATOM   5203  C CB   . TYR A 1 381 ? 2.608   -1.927  33.752 1.00 12.07 ?  347  TYR A CB   1 
ATOM   5204  C CG   . TYR A 1 381 ? 1.688   -0.810  34.190 1.00 12.73 ?  347  TYR A CG   1 
ATOM   5205  C CD1  . TYR A 1 381 ? 0.501   -1.049  34.853 1.00 13.69 ?  347  TYR A CD1  1 
ATOM   5206  C CD2  . TYR A 1 381 ? 2.032   0.500   33.921 1.00 13.41 ?  347  TYR A CD2  1 
ATOM   5207  C CE1  . TYR A 1 381 ? -0.330  0.010   35.234 1.00 19.26 ?  347  TYR A CE1  1 
ATOM   5208  C CE2  . TYR A 1 381 ? 1.221   1.551   34.296 1.00 15.11 ?  347  TYR A CE2  1 
ATOM   5209  C CZ   . TYR A 1 381 ? 0.055   1.301   34.951 1.00 17.08 ?  347  TYR A CZ   1 
ATOM   5210  O OH   . TYR A 1 381 ? -0.739  2.368   35.319 1.00 21.74 ?  347  TYR A OH   1 
ATOM   5211  H H    . TYR A 1 381 ? 2.861   -2.786  36.061 1.00 15.18 ?  347  TYR A H    1 
ATOM   5212  H HA   . TYR A 1 381 ? 1.388   -3.577  33.985 1.00 14.33 ?  347  TYR A HA   1 
ATOM   5213  H HB2  . TYR A 1 381 ? 3.499   -1.694  34.056 1.00 14.48 ?  347  TYR A HB2  1 
ATOM   5214  H HB3  . TYR A 1 381 ? 2.584   -1.948  32.782 1.00 14.48 ?  347  TYR A HB3  1 
ATOM   5215  H HD1  . TYR A 1 381 ? 0.251   -1.923  35.049 1.00 16.43 ?  347  TYR A HD1  1 
ATOM   5216  H HD2  . TYR A 1 381 ? 2.829   0.678   33.477 1.00 16.09 ?  347  TYR A HD2  1 
ATOM   5217  H HE1  . TYR A 1 381 ? -1.133  -0.156  35.673 1.00 23.11 ?  347  TYR A HE1  1 
ATOM   5218  H HE2  . TYR A 1 381 ? 1.470   2.425   34.102 1.00 18.14 ?  347  TYR A HE2  1 
ATOM   5219  H HH   . TYR A 1 381 ? -0.499  3.060   34.907 1.00 26.09 ?  347  TYR A HH   1 
ATOM   5220  N N    . LYS A 1 382 ? 4.268   -4.789  34.391 1.00 13.52 ?  348  LYS A N    1 
ATOM   5221  C CA   . LYS A 1 382 ? 5.311   -5.644  33.843 1.00 14.80 ?  348  LYS A CA   1 
ATOM   5222  C C    . LYS A 1 382 ? 5.071   -7.124  34.106 1.00 13.50 ?  348  LYS A C    1 
ATOM   5223  O O    . LYS A 1 382 ? 5.639   -7.964  33.400 1.00 16.36 ?  348  LYS A O    1 
ATOM   5224  C CB   . LYS A 1 382 ? 6.670   -5.309  34.475 1.00 19.15 ?  348  LYS A CB   1 
ATOM   5225  C CG   . LYS A 1 382 ? 7.067   -3.838  34.461 1.00 24.96 ?  348  LYS A CG   1 
ATOM   5226  C CD   . LYS A 1 382 ? 8.142   -3.583  35.521 1.00 29.86 ?  348  LYS A CD   1 
ATOM   5227  C CE   . LYS A 1 382 ? 8.570   -2.124  35.569 1.00 31.57 ?  348  LYS A CE   1 
ATOM   5228  N NZ   . LYS A 1 382 ? 9.821   -1.959  36.362 1.00 37.67 ?  348  LYS A NZ   1 
ATOM   5229  H H    . LYS A 1 382 ? 4.345   -4.640  35.234 1.00 16.22 ?  348  LYS A H    1 
ATOM   5230  H HA   . LYS A 1 382 ? 5.350   -5.484  32.887 1.00 17.76 ?  348  LYS A HA   1 
ATOM   5231  H HB2  . LYS A 1 382 ? 6.651   -5.592  35.402 1.00 22.98 ?  348  LYS A HB2  1 
ATOM   5232  H HB3  . LYS A 1 382 ? 7.357   -5.796  33.993 1.00 22.98 ?  348  LYS A HB3  1 
ATOM   5233  H HG2  . LYS A 1 382 ? 7.425   -3.603  33.591 1.00 29.95 ?  348  LYS A HG2  1 
ATOM   5234  H HG3  . LYS A 1 382 ? 6.294   -3.288  34.661 1.00 29.95 ?  348  LYS A HG3  1 
ATOM   5235  H HD2  . LYS A 1 382 ? 7.792   -3.823  36.393 1.00 35.84 ?  348  LYS A HD2  1 
ATOM   5236  H HD3  . LYS A 1 382 ? 8.923   -4.120  35.318 1.00 35.84 ?  348  LYS A HD3  1 
ATOM   5237  H HE2  . LYS A 1 382 ? 8.734   -1.806  34.667 1.00 37.89 ?  348  LYS A HE2  1 
ATOM   5238  H HE3  . LYS A 1 382 ? 7.871   -1.596  35.985 1.00 37.89 ?  348  LYS A HE3  1 
ATOM   5239  H HZ1  . LYS A 1 382 ? 10.056  -1.101  36.385 1.00 45.21 ?  348  LYS A HZ1  1 
ATOM   5240  H HZ2  . LYS A 1 382 ? 9.693   -2.246  37.195 1.00 45.21 ?  348  LYS A HZ2  1 
ATOM   5241  H HZ3  . LYS A 1 382 ? 10.480  -2.429  35.992 1.00 45.21 ?  348  LYS A HZ3  1 
ATOM   5242  N N    . LYS A 1 383 ? 4.270   -7.447  35.106 1.00 12.82 ?  349  LYS A N    1 
ATOM   5243  C CA   . LYS A 1 383 ? 4.051   -8.832  35.492 1.00 13.22 ?  349  LYS A CA   1 
ATOM   5244  C C    . LYS A 1 383 ? 3.153   -9.544  34.488 1.00 16.06 ?  349  LYS A C    1 
ATOM   5245  O O    . LYS A 1 383 ? 2.300   -8.937  33.831 1.00 14.81 ?  349  LYS A O    1 
ATOM   5246  C CB   . LYS A 1 383 ? 3.423   -8.878  36.877 1.00 14.59 ?  349  LYS A CB   1 
ATOM   5247  C CG   . LYS A 1 383 ? 4.401   -8.494  37.994 1.00 16.05 ?  349  LYS A CG   1 
ATOM   5248  C CD   . LYS A 1 383 ? 3.741   -8.359  39.348 1.00 17.39 ?  349  LYS A CD   1 
ATOM   5249  C CE   . LYS A 1 383 ? 4.780   -7.945  40.392 1.00 20.53 ?  349  LYS A CE   1 
ATOM   5250  N NZ   . LYS A 1 383 ? 4.205   -7.922  41.756 1.00 25.96 ?  349  LYS A NZ   1 
ATOM   5251  H H    . LYS A 1 383 ? 3.835   -6.879  35.583 1.00 15.38 ?  349  LYS A H    1 
ATOM   5252  H HA   . LYS A 1 383 ? 4.898   -9.304  35.515 1.00 15.86 ?  349  LYS A HA   1 
ATOM   5253  H HB2  . LYS A 1 383 ? 2.679   -8.256  36.905 1.00 17.50 ?  349  LYS A HB2  1 
ATOM   5254  H HB3  . LYS A 1 383 ? 3.110   -9.779  37.050 1.00 17.50 ?  349  LYS A HB3  1 
ATOM   5255  H HG2  . LYS A 1 383 ? 5.083   -9.180  38.063 1.00 19.26 ?  349  LYS A HG2  1 
ATOM   5256  H HG3  . LYS A 1 383 ? 4.809   -7.642  37.775 1.00 19.26 ?  349  LYS A HG3  1 
ATOM   5257  H HD2  . LYS A 1 383 ? 3.051   -7.679  39.309 1.00 20.87 ?  349  LYS A HD2  1 
ATOM   5258  H HD3  . LYS A 1 383 ? 3.356   -9.209  39.611 1.00 20.87 ?  349  LYS A HD3  1 
ATOM   5259  H HE2  . LYS A 1 383 ? 5.514   -8.579  40.382 1.00 24.64 ?  349  LYS A HE2  1 
ATOM   5260  H HE3  . LYS A 1 383 ? 5.107   -7.056  40.184 1.00 24.64 ?  349  LYS A HE3  1 
ATOM   5261  H HZ1  . LYS A 1 383 ? 4.820   -7.652  42.340 1.00 31.15 ?  349  LYS A HZ1  1 
ATOM   5262  H HZ2  . LYS A 1 383 ? 3.513   -7.363  41.785 1.00 31.15 ?  349  LYS A HZ2  1 
ATOM   5263  H HZ3  . LYS A 1 383 ? 3.929   -8.736  41.983 1.00 31.15 ?  349  LYS A HZ3  1 
ATOM   5264  N N    . ALA A 1 384 ? 3.370   -10.857 34.366 1.00 14.99 ?  350  ALA A N    1 
ATOM   5265  C CA   . ALA A 1 384 ? 2.590   -11.684 33.454 1.00 13.61 ?  350  ALA A CA   1 
ATOM   5266  C C    . ALA A 1 384 ? 1.130   -11.667 33.862 1.00 12.34 ?  350  ALA A C    1 
ATOM   5267  O O    . ALA A 1 384 ? 0.782   -11.899 35.019 1.00 13.70 ?  350  ALA A O    1 
ATOM   5268  C CB   . ALA A 1 384 ? 3.112   -13.131 33.449 1.00 14.28 ?  350  ALA A CB   1 
ATOM   5269  H H    . ALA A 1 384 ? 3.967   -11.293 34.805 1.00 17.99 ?  350  ALA A H    1 
ATOM   5270  H HA   . ALA A 1 384 ? 2.675   -11.330 32.554 1.00 16.33 ?  350  ALA A HA   1 
ATOM   5271  H HB1  . ALA A 1 384 ? 2.598   -13.651 32.811 1.00 17.13 ?  350  ALA A HB1  1 
ATOM   5272  H HB2  . ALA A 1 384 ? 4.048   -13.129 33.195 1.00 17.13 ?  350  ALA A HB2  1 
ATOM   5273  H HB3  . ALA A 1 384 ? 3.012   -13.506 34.338 1.00 17.13 ?  350  ALA A HB3  1 
ATOM   5274  N N    . LEU A 1 385 ? 0.268   -11.367 32.893 1.00 12.28 ?  351  LEU A N    1 
ATOM   5275  C CA   . LEU A 1 385 ? -1.163  -11.281 33.115 1.00 12.65 ?  351  LEU A CA   1 
ATOM   5276  C C    . LEU A 1 385 ? -1.826  -12.531 32.547 1.00 12.88 ?  351  LEU A C    1 
ATOM   5277  O O    . LEU A 1 385 ? -2.378  -13.334 33.307 1.00 13.67 ?  351  LEU A O    1 
ATOM   5278  C CB   . LEU A 1 385 ? -1.692  -9.985  32.481 1.00 11.43 ?  351  LEU A CB   1 
ATOM   5279  C CG   . LEU A 1 385 ? -3.209  -9.813  32.396 1.00 11.30 ?  351  LEU A CG   1 
ATOM   5280  C CD1  . LEU A 1 385 ? -3.799  -9.822  33.768 1.00 12.63 ?  351  LEU A CD1  1 
ATOM   5281  C CD2  . LEU A 1 385 ? -3.578  -8.497  31.682 1.00 11.64 ?  351  LEU A CD2  1 
ATOM   5282  H H    . LEU A 1 385 ? 0.497   -11.206 32.080 1.00 14.74 ?  351  LEU A H    1 
ATOM   5283  H HA   . LEU A 1 385 ? -1.384  -11.241 34.058 1.00 15.17 ?  351  LEU A HA   1 
ATOM   5284  H HB2  . LEU A 1 385 ? -1.353  -9.240  33.002 1.00 13.71 ?  351  LEU A HB2  1 
ATOM   5285  H HB3  . LEU A 1 385 ? -1.353  -9.937  31.574 1.00 13.71 ?  351  LEU A HB3  1 
ATOM   5286  H HG   . LEU A 1 385 ? -3.579  -10.548 31.882 1.00 13.56 ?  351  LEU A HG   1 
ATOM   5287  H HD11 . LEU A 1 385 ? -4.757  -9.690  33.700 1.00 15.16 ?  351  LEU A HD11 1 
ATOM   5288  H HD12 . LEU A 1 385 ? -3.612  -10.677 34.186 1.00 15.16 ?  351  LEU A HD12 1 
ATOM   5289  H HD13 . LEU A 1 385 ? -3.401  -9.106  34.287 1.00 15.16 ?  351  LEU A HD13 1 
ATOM   5290  H HD21 . LEU A 1 385 ? -4.529  -8.496  31.494 1.00 13.97 ?  351  LEU A HD21 1 
ATOM   5291  H HD22 . LEU A 1 385 ? -3.354  -7.751  32.260 1.00 13.97 ?  351  LEU A HD22 1 
ATOM   5292  H HD23 . LEU A 1 385 ? -3.077  -8.436  30.854 1.00 13.97 ?  351  LEU A HD23 1 
ATOM   5293  N N    . GLY A 1 386 ? -1.770  -12.703 31.237 1.00 12.03 ?  352  GLY A N    1 
ATOM   5294  C CA   . GLY A 1 386 ? -2.403  -13.831 30.577 1.00 11.79 ?  352  GLY A CA   1 
ATOM   5295  C C    . GLY A 1 386 ? -3.871  -13.581 30.270 1.00 11.05 ?  352  GLY A C    1 
ATOM   5296  O O    . GLY A 1 386 ? -4.521  -12.706 30.833 1.00 12.62 ?  352  GLY A O    1 
ATOM   5297  H H    . GLY A 1 386 ? -1.364  -12.170 30.698 1.00 14.43 ?  352  GLY A H    1 
ATOM   5298  H HA2  . GLY A 1 386 ? -1.943  -14.012 29.742 1.00 14.15 ?  352  GLY A HA2  1 
ATOM   5299  H HA3  . GLY A 1 386 ? -2.339  -14.613 31.147 1.00 14.15 ?  352  GLY A HA3  1 
ATOM   5300  N N    . ALA A 1 387 ? -4.407  -14.383 29.358 1.00 11.41 ?  353  ALA A N    1 
ATOM   5301  C CA   . ALA A 1 387 ? -5.785  -14.194 28.943 1.00 11.95 ?  353  ALA A CA   1 
ATOM   5302  C C    . ALA A 1 387 ? -6.756  -14.604 30.056 1.00 11.74 ?  353  ALA A C    1 
ATOM   5303  O O    . ALA A 1 387 ? -6.433  -15.455 30.898 1.00 12.05 ?  353  ALA A O    1 
ATOM   5304  C CB   . ALA A 1 387 ? -6.059  -15.022 27.694 1.00 13.68 ?  353  ALA A CB   1 
ATOM   5305  H H    . ALA A 1 387 ? -3.999  -15.034 28.971 1.00 13.69 ?  353  ALA A H    1 
ATOM   5306  H HA   . ALA A 1 387 ? -5.940  -13.257 28.746 1.00 14.34 ?  353  ALA A HA   1 
ATOM   5307  H HB1  . ALA A 1 387 ? -6.960  -14.838 27.385 1.00 16.41 ?  353  ALA A HB1  1 
ATOM   5308  H HB2  . ALA A 1 387 ? -5.418  -14.781 27.007 1.00 16.41 ?  353  ALA A HB2  1 
ATOM   5309  H HB3  . ALA A 1 387 ? -5.970  -15.963 27.913 1.00 16.41 ?  353  ALA A HB3  1 
ATOM   5310  N N    . PRO A 1 388 ? -7.965  -14.036 30.065 1.00 11.11 ?  354  PRO A N    1 
ATOM   5311  C CA   . PRO A 1 388 ? -8.948  -14.442 31.076 1.00 13.37 ?  354  PRO A CA   1 
ATOM   5312  C C    . PRO A 1 388 ? -9.280  -15.919 30.938 1.00 13.96 ?  354  PRO A C    1 
ATOM   5313  O O    . PRO A 1 388 ? -9.305  -16.472 29.836 1.00 13.97 ?  354  PRO A O    1 
ATOM   5314  C CB   . PRO A 1 388 ? -10.173 -13.570 30.781 1.00 12.59 ?  354  PRO A CB   1 
ATOM   5315  C CG   . PRO A 1 388 ? -9.901  -12.905 29.460 1.00 21.50 ?  354  PRO A CG   1 
ATOM   5316  C CD   . PRO A 1 388 ? -8.434  -12.922 29.219 1.00 13.62 ?  354  PRO A CD   1 
ATOM   5317  H HA   . PRO A 1 388 ? -8.625  -14.246 31.969 1.00 16.05 ?  354  PRO A HA   1 
ATOM   5318  H HB2  . PRO A 1 388 ? -10.965 -14.127 30.729 1.00 15.10 ?  354  PRO A HB2  1 
ATOM   5319  H HB3  . PRO A 1 388 ? -10.278 -12.908 31.483 1.00 15.10 ?  354  PRO A HB3  1 
ATOM   5320  H HG2  . PRO A 1 388 ? -10.361 -13.394 28.759 1.00 25.80 ?  354  PRO A HG2  1 
ATOM   5321  H HG3  . PRO A 1 388 ? -10.224 -11.991 29.493 1.00 25.80 ?  354  PRO A HG3  1 
ATOM   5322  H HD2  . PRO A 1 388 ? -8.239  -13.093 28.284 1.00 16.34 ?  354  PRO A HD2  1 
ATOM   5323  H HD3  . PRO A 1 388 ? -8.029  -12.085 29.494 1.00 16.34 ?  354  PRO A HD3  1 
ATOM   5324  N N    . LEU A 1 389 ? -9.552  -16.545 32.080 1.00 12.89 ?  355  LEU A N    1 
ATOM   5325  C CA   . LEU A 1 389 ? -10.070 -17.907 32.138 1.00 13.43 ?  355  LEU A CA   1 
ATOM   5326  C C    . LEU A 1 389 ? -11.573 -17.929 32.300 1.00 15.91 ?  355  LEU A C    1 
ATOM   5327  O O    . LEU A 1 389 ? -12.188 -19.000 32.236 1.00 15.10 ?  355  LEU A O    1 
ATOM   5328  C CB   . LEU A 1 389 ? -9.415  -18.661 33.285 1.00 13.97 ?  355  LEU A CB   1 
ATOM   5329  C CG   . LEU A 1 389 ? -7.935  -18.906 33.060 1.00 15.74 ?  355  LEU A CG   1 
ATOM   5330  C CD1  . LEU A 1 389 ? -7.296  -19.450 34.323 1.00 21.33 ?  355  LEU A CD1  1 
ATOM   5331  C CD2  . LEU A 1 389 ? -7.732  -19.851 31.890 1.00 21.70 ?  355  LEU A CD2  1 
ATOM   5332  H H    . LEU A 1 389 ? -9.441  -16.191 32.856 1.00 15.47 ?  355  LEU A H    1 
ATOM   5333  H HA   . LEU A 1 389 ? -9.848  -18.380 31.321 1.00 16.12 ?  355  LEU A HA   1 
ATOM   5334  H HB2  . LEU A 1 389 ? -9.514  -18.143 34.099 1.00 16.76 ?  355  LEU A HB2  1 
ATOM   5335  H HB3  . LEU A 1 389 ? -9.850  -19.522 33.384 1.00 16.76 ?  355  LEU A HB3  1 
ATOM   5336  H HG   . LEU A 1 389 ? -7.495  -18.069 32.844 1.00 18.89 ?  355  LEU A HG   1 
ATOM   5337  H HD11 . LEU A 1 389 ? -6.359  -19.633 34.149 1.00 25.60 ?  355  LEU A HD11 1 
ATOM   5338  H HD12 . LEU A 1 389 ? -7.379  -18.790 35.028 1.00 25.60 ?  355  LEU A HD12 1 
ATOM   5339  H HD13 . LEU A 1 389 ? -7.751  -20.268 34.579 1.00 25.60 ?  355  LEU A HD13 1 
ATOM   5340  H HD21 . LEU A 1 389 ? -6.812  -20.159 31.888 1.00 26.04 ?  355  LEU A HD21 1 
ATOM   5341  H HD22 . LEU A 1 389 ? -8.333  -20.606 31.986 1.00 26.04 ?  355  LEU A HD22 1 
ATOM   5342  H HD23 . LEU A 1 389 ? -7.924  -19.378 31.065 1.00 26.04 ?  355  LEU A HD23 1 
ATOM   5343  N N    . GLY A 1 390 ? -12.175 -16.777 32.516 1.00 20.20 ?  356  GLY A N    1 
ATOM   5344  C CA   . GLY A 1 390 ? -13.612 -16.656 32.449 1.00 18.82 ?  356  GLY A CA   1 
ATOM   5345  C C    . GLY A 1 390 ? -13.994 -15.224 32.726 1.00 17.28 ?  356  GLY A C    1 
ATOM   5346  O O    . GLY A 1 390 ? -13.154 -14.385 33.072 1.00 16.98 ?  356  GLY A O    1 
ATOM   5347  H H    . GLY A 1 390 ? -11.769 -16.043 32.704 1.00 24.23 ?  356  GLY A H    1 
ATOM   5348  H HA2  . GLY A 1 390 ? -13.929 -16.906 31.568 1.00 22.58 ?  356  GLY A HA2  1 
ATOM   5349  H HA3  . GLY A 1 390 ? -14.028 -17.231 33.110 1.00 22.58 ?  356  GLY A HA3  1 
ATOM   5350  N N    . LYS A 1 391 ? -15.285 -14.968 32.589 1.00 15.21 ?  357  LYS A N    1 
ATOM   5351  C CA   . LYS A 1 391 ? -15.842 -13.682 32.955 1.00 14.48 ?  357  LYS A CA   1 
ATOM   5352  C C    . LYS A 1 391 ? -15.726 -13.459 34.460 1.00 16.61 ?  357  LYS A C    1 
ATOM   5353  O O    . LYS A 1 391 ? -15.558 -14.389 35.254 1.00 16.72 ?  357  LYS A O    1 
ATOM   5354  C CB   . LYS A 1 391 ? -17.307 -13.622 32.532 1.00 13.85 ?  357  LYS A CB   1 
ATOM   5355  C CG   . LYS A 1 391 ? -17.482 -13.516 31.030 1.00 19.39 ?  357  LYS A CG   1 
ATOM   5356  C CD   . LYS A 1 391 ? -18.909 -13.750 30.589 1.00 28.37 ?  357  LYS A CD   1 
ATOM   5357  C CE   . LYS A 1 391 ? -19.131 -13.223 29.170 1.00 27.28 ?  357  LYS A CE   1 
ATOM   5358  N NZ   . LYS A 1 391 ? -18.257 -13.901 28.146 1.00 22.27 ?  357  LYS A NZ   1 
ATOM   5359  H H    . LYS A 1 391 ? -15.862 -15.527 32.283 1.00 18.25 ?  357  LYS A H    1 
ATOM   5360  H HA   . LYS A 1 391 ? -15.358 -12.970 32.509 1.00 17.38 ?  357  LYS A HA   1 
ATOM   5361  H HB2  . LYS A 1 391 ? -17.754 -14.429 32.830 1.00 16.62 ?  357  LYS A HB2  1 
ATOM   5362  H HB3  . LYS A 1 391 ? -17.721 -12.844 32.938 1.00 16.62 ?  357  LYS A HB3  1 
ATOM   5363  H HG2  . LYS A 1 391 ? -17.222 -12.627 30.743 1.00 23.27 ?  357  LYS A HG2  1 
ATOM   5364  H HG3  . LYS A 1 391 ? -16.922 -14.181 30.599 1.00 23.27 ?  357  LYS A HG3  1 
ATOM   5365  H HD2  . LYS A 1 391 ? -19.100 -14.701 30.597 1.00 34.04 ?  357  LYS A HD2  1 
ATOM   5366  H HD3  . LYS A 1 391 ? -19.514 -13.285 31.188 1.00 34.04 ?  357  LYS A HD3  1 
ATOM   5367  H HE2  . LYS A 1 391 ? -20.056 -13.373 28.919 1.00 32.73 ?  357  LYS A HE2  1 
ATOM   5368  H HE3  . LYS A 1 391 ? -18.932 -12.274 29.152 1.00 32.73 ?  357  LYS A HE3  1 
ATOM   5369  H HZ1  . LYS A 1 391 ? -18.452 -13.600 27.332 1.00 26.72 ?  357  LYS A HZ1  1 
ATOM   5370  H HZ2  . LYS A 1 391 ? -17.400 -13.732 28.318 1.00 26.72 ?  357  LYS A HZ2  1 
ATOM   5371  H HZ3  . LYS A 1 391 ? -18.388 -14.781 28.168 1.00 26.72 ?  357  LYS A HZ3  1 
ATOM   5372  N N    . ALA A 1 392 ? -15.815 -12.198 34.857 1.00 14.10 ?  358  ALA A N    1 
ATOM   5373  C CA   . ALA A 1 392 ? -15.874 -11.885 36.271 1.00 13.12 ?  358  ALA A CA   1 
ATOM   5374  C C    . ALA A 1 392 ? -17.117 -12.505 36.890 1.00 14.51 ?  358  ALA A C    1 
ATOM   5375  O O    . ALA A 1 392 ? -18.150 -12.670 36.243 1.00 16.49 ?  358  ALA A O    1 
ATOM   5376  C CB   . ALA A 1 392 ? -15.923 -10.371 36.458 1.00 13.83 ?  358  ALA A CB   1 
ATOM   5377  H H    . ALA A 1 392 ? -15.841 -11.516 34.334 1.00 16.92 ?  358  ALA A H    1 
ATOM   5378  H HA   . ALA A 1 392 ? -15.090 -12.236 36.721 1.00 15.75 ?  358  ALA A HA   1 
ATOM   5379  H HB1  . ALA A 1 392 ? -15.965 -10.171 37.406 1.00 16.60 ?  358  ALA A HB1  1 
ATOM   5380  H HB2  . ALA A 1 392 ? -15.124 -9.979  36.071 1.00 16.60 ?  358  ALA A HB2  1 
ATOM   5381  H HB3  . ALA A 1 392 ? -16.711 -10.023 36.011 1.00 16.60 ?  358  ALA A HB3  1 
ATOM   5382  N N    . ILE A 1 393 ? -16.997 -12.867 38.163 1.00 16.32 ?  359  ILE A N    1 
ATOM   5383  C CA   . ILE A 1 393 ? -18.117 -13.339 38.962 1.00 17.11 ?  359  ILE A CA   1 
ATOM   5384  C C    . ILE A 1 393 ? -18.459 -12.255 39.967 1.00 14.20 ?  359  ILE A C    1 
ATOM   5385  O O    . ILE A 1 393 ? -17.589 -11.809 40.725 1.00 16.65 ?  359  ILE A O    1 
ATOM   5386  C CB   . ILE A 1 393 ? -17.762 -14.654 39.677 1.00 20.23 ?  359  ILE A CB   1 
ATOM   5387  C CG1  . ILE A 1 393 ? -17.431 -15.732 38.646 1.00 21.05 ?  359  ILE A CG1  1 
ATOM   5388  C CG2  . ILE A 1 393 ? -18.896 -15.088 40.586 1.00 21.98 ?  359  ILE A CG2  1 
ATOM   5389  C CD1  . ILE A 1 393 ? -16.793 -16.977 39.243 1.00 24.14 ?  359  ILE A CD1  1 
ATOM   5390  H H    . ILE A 1 393 ? -16.255 -12.845 38.596 1.00 19.59 ?  359  ILE A H    1 
ATOM   5391  H HA   . ILE A 1 393 ? -18.889 -13.492 38.394 1.00 20.53 ?  359  ILE A HA   1 
ATOM   5392  H HB   . ILE A 1 393 ? -16.979 -14.511 40.231 1.00 24.27 ?  359  ILE A HB   1 
ATOM   5393  H HG12 . ILE A 1 393 ? -18.251 -16.003 38.203 1.00 25.25 ?  359  ILE A HG12 1 
ATOM   5394  H HG13 . ILE A 1 393 ? -16.811 -15.363 37.997 1.00 25.25 ?  359  ILE A HG13 1 
ATOM   5395  H HG21 . ILE A 1 393 ? -18.780 -16.025 40.810 1.00 26.38 ?  359  ILE A HG21 1 
ATOM   5396  H HG22 . ILE A 1 393 ? -18.878 -14.550 41.392 1.00 26.38 ?  359  ILE A HG22 1 
ATOM   5397  H HG23 . ILE A 1 393 ? -19.739 -14.962 40.122 1.00 26.38 ?  359  ILE A HG23 1 
ATOM   5398  H HD11 . ILE A 1 393 ? -16.409 -17.509 38.529 1.00 28.97 ?  359  ILE A HD11 1 
ATOM   5399  H HD12 . ILE A 1 393 ? -16.099 -16.708 39.865 1.00 28.97 ?  359  ILE A HD12 1 
ATOM   5400  H HD13 . ILE A 1 393 ? -17.474 -17.489 39.708 1.00 28.97 ?  359  ILE A HD13 1 
ATOM   5401  N N    . LYS A 1 394 ? -19.729 -11.872 40.001 1.00 15.32 ?  360  LYS A N    1 
ATOM   5402  C CA   . LYS A 1 394 ? -20.225 -10.814 40.868 1.00 17.88 ?  360  LYS A CA   1 
ATOM   5403  C C    . LYS A 1 394 ? -21.060 -11.427 41.981 1.00 19.83 ?  360  LYS A C    1 
ATOM   5404  O O    . LYS A 1 394 ? -21.984 -12.204 41.710 1.00 19.77 ?  360  LYS A O    1 
ATOM   5405  C CB   . LYS A 1 394 ? -21.093 -9.843  40.065 1.00 17.01 ?  360  LYS A CB   1 
ATOM   5406  C CG   . LYS A 1 394 ? -21.670 -8.687  40.886 1.00 18.28 ?  360  LYS A CG   1 
ATOM   5407  C CD   . LYS A 1 394 ? -22.547 -7.786  40.031 1.00 21.10 ?  360  LYS A CD   1 
ATOM   5408  C CE   . LYS A 1 394 ? -23.028 -6.553  40.789 1.00 22.10 ?  360  LYS A CE   1 
ATOM   5409  N NZ   . LYS A 1 394 ? -23.916 -6.923  41.925 1.00 24.16 ?  360  LYS A NZ   1 
ATOM   5410  H H    . LYS A 1 394 ? -20.343 -12.223 39.512 1.00 18.38 ?  360  LYS A H    1 
ATOM   5411  H HA   . LYS A 1 394 ? -19.479 -10.335 41.262 1.00 21.46 ?  360  LYS A HA   1 
ATOM   5412  H HB2  . LYS A 1 394 ? -20.553 -9.460  39.356 1.00 20.41 ?  360  LYS A HB2  1 
ATOM   5413  H HB3  . LYS A 1 394 ? -21.838 -10.335 39.686 1.00 20.41 ?  360  LYS A HB3  1 
ATOM   5414  H HG2  . LYS A 1 394 ? -22.210 -9.043  41.608 1.00 21.93 ?  360  LYS A HG2  1 
ATOM   5415  H HG3  . LYS A 1 394 ? -20.944 -8.154  41.246 1.00 21.93 ?  360  LYS A HG3  1 
ATOM   5416  H HD2  . LYS A 1 394 ? -22.040 -7.487  39.260 1.00 25.33 ?  360  LYS A HD2  1 
ATOM   5417  H HD3  . LYS A 1 394 ? -23.327 -8.284  39.741 1.00 25.33 ?  360  LYS A HD3  1 
ATOM   5418  H HE2  . LYS A 1 394 ? -22.262 -6.075  41.143 1.00 26.52 ?  360  LYS A HE2  1 
ATOM   5419  H HE3  . LYS A 1 394 ? -23.526 -5.979  40.186 1.00 26.52 ?  360  LYS A HE3  1 
ATOM   5420  H HZ1  . LYS A 1 394 ? -24.608 -7.399  41.628 1.00 28.99 ?  360  LYS A HZ1  1 
ATOM   5421  H HZ2  . LYS A 1 394 ? -23.465 -7.408  42.519 1.00 28.99 ?  360  LYS A HZ2  1 
ATOM   5422  H HZ3  . LYS A 1 394 ? -24.222 -6.188  42.324 1.00 28.99 ?  360  LYS A HZ3  1 
ATOM   5423  N N    . ASN A 1 395 ? -20.740 -11.062 43.221 1.00 18.02 ?  361  ASN A N    1 
ATOM   5424  C CA   . ASN A 1 395 ? -21.515 -11.440 44.403 1.00 21.29 ?  361  ASN A CA   1 
ATOM   5425  C C    . ASN A 1 395 ? -21.668 -10.174 45.241 1.00 16.37 ?  361  ASN A C    1 
ATOM   5426  O O    . ASN A 1 395 ? -20.772 -9.815  46.011 1.00 17.96 ?  361  ASN A O    1 
ATOM   5427  C CB   . ASN A 1 395 ? -20.816 -12.535 45.187 1.00 25.86 ?  361  ASN A CB   1 
ATOM   5428  C CG   . ASN A 1 395 ? -21.692 -13.109 46.271 1.00 32.82 ?  361  ASN A CG   1 
ATOM   5429  O OD1  . ASN A 1 395 ? -22.625 -12.459 46.736 1.00 39.03 ?  361  ASN A OD1  1 
ATOM   5430  N ND2  . ASN A 1 395 ? -21.401 -14.338 46.680 1.00 48.08 ?  361  ASN A ND2  1 
ATOM   5431  H H    . ASN A 1 395 ? -20.054 -10.579 43.410 1.00 21.62 ?  361  ASN A H    1 
ATOM   5432  H HA   . ASN A 1 395 ? -22.391 -11.767 44.143 1.00 25.55 ?  361  ASN A HA   1 
ATOM   5433  H HB2  . ASN A 1 395 ? -20.573 -13.253 44.582 1.00 31.03 ?  361  ASN A HB2  1 
ATOM   5434  H HB3  . ASN A 1 395 ? -20.020 -12.169 45.603 1.00 31.03 ?  361  ASN A HB3  1 
ATOM   5435  H HD21 . ASN A 1 395 ? -20.741 -14.763 46.328 1.00 57.70 ?  361  ASN A HD21 1 
ATOM   5436  H HD22 . ASN A 1 395 ? -21.871 -14.709 47.297 1.00 57.70 ?  361  ASN A HD22 1 
ATOM   5437  N N    . GLY A 1 396 ? -22.808 -9.518  45.103 1.00 17.89 ?  362  GLY A N    1 
ATOM   5438  C CA   . GLY A 1 396 ? -22.975 -8.227  45.751 1.00 20.20 ?  362  GLY A CA   1 
ATOM   5439  C C    . GLY A 1 396 ? -21.994 -7.226  45.170 1.00 18.51 ?  362  GLY A C    1 
ATOM   5440  O O    . GLY A 1 396 ? -21.927 -7.038  43.951 1.00 19.94 ?  362  GLY A O    1 
ATOM   5441  H H    . GLY A 1 396 ? -23.487 -9.791  44.650 1.00 21.47 ?  362  GLY A H    1 
ATOM   5442  H HA2  . GLY A 1 396 ? -23.878 -7.901  45.613 1.00 24.25 ?  362  GLY A HA2  1 
ATOM   5443  H HA3  . GLY A 1 396 ? -22.813 -8.311  46.704 1.00 24.25 ?  362  GLY A HA3  1 
ATOM   5444  N N    . TYR A 1 397 ? -21.209 -6.589  46.035 1.00 18.88 ?  363  TYR A N    1 
ATOM   5445  C CA   . TYR A 1 397 ? -20.196 -5.630  45.614 1.00 16.09 ?  363  TYR A CA   1 
ATOM   5446  C C    . TYR A 1 397 ? -18.822 -6.272  45.494 1.00 18.17 ?  363  TYR A C    1 
ATOM   5447  O O    . TYR A 1 397 ? -17.830 -5.564  45.306 1.00 18.87 ?  363  TYR A O    1 
ATOM   5448  C CB   . TYR A 1 397 ? -20.141 -4.442  46.580 1.00 19.16 ?  363  TYR A CB   1 
ATOM   5449  C CG   . TYR A 1 397 ? -21.414 -3.634  46.620 1.00 19.45 ?  363  TYR A CG   1 
ATOM   5450  C CD1  . TYR A 1 397 ? -21.975 -3.125  45.462 1.00 19.42 ?  363  TYR A CD1  1 
ATOM   5451  C CD2  . TYR A 1 397 ? -22.047 -3.362  47.826 1.00 25.10 ?  363  TYR A CD2  1 
ATOM   5452  C CE1  . TYR A 1 397 ? -23.136 -2.388  45.499 1.00 21.62 ?  363  TYR A CE1  1 
ATOM   5453  C CE2  . TYR A 1 397 ? -23.208 -2.620  47.872 1.00 30.38 ?  363  TYR A CE2  1 
ATOM   5454  C CZ   . TYR A 1 397 ? -23.751 -2.136  46.710 1.00 24.76 ?  363  TYR A CZ   1 
ATOM   5455  O OH   . TYR A 1 397 ? -24.917 -1.396  46.752 1.00 32.24 ?  363  TYR A OH   1 
ATOM   5456  H H    . TYR A 1 397 ? -21.247 -6.699  46.887 1.00 22.66 ?  363  TYR A H    1 
ATOM   5457  H HA   . TYR A 1 397 ? -20.445 -5.279  44.745 1.00 19.31 ?  363  TYR A HA   1 
ATOM   5458  H HB2  . TYR A 1 397 ? -19.973 -4.776  47.475 1.00 22.99 ?  363  TYR A HB2  1 
ATOM   5459  H HB3  . TYR A 1 397 ? -19.422 -3.851  46.306 1.00 22.99 ?  363  TYR A HB3  1 
ATOM   5460  H HD1  . TYR A 1 397 ? -21.561 -3.283  44.644 1.00 23.30 ?  363  TYR A HD1  1 
ATOM   5461  H HD2  . TYR A 1 397 ? -21.681 -3.686  48.617 1.00 30.12 ?  363  TYR A HD2  1 
ATOM   5462  H HE1  . TYR A 1 397 ? -23.507 -2.061  44.712 1.00 25.94 ?  363  TYR A HE1  1 
ATOM   5463  H HE2  . TYR A 1 397 ? -23.621 -2.449  48.687 1.00 36.46 ?  363  TYR A HE2  1 
ATOM   5464  H HH   . TYR A 1 397 ? -25.182 -1.323  47.545 1.00 38.69 ?  363  TYR A HH   1 
ATOM   5465  N N    . ILE A 1 398 ? -18.736 -7.594  45.614 1.00 17.13 ?  364  ILE A N    1 
ATOM   5466  C CA   . ILE A 1 398 ? -17.477 -8.310  45.489 1.00 16.27 ?  364  ILE A CA   1 
ATOM   5467  C C    . ILE A 1 398 ? -17.435 -8.976  44.124 1.00 19.67 ?  364  ILE A C    1 
ATOM   5468  O O    . ILE A 1 398 ? -18.389 -9.667  43.727 1.00 19.49 ?  364  ILE A O    1 
ATOM   5469  C CB   . ILE A 1 398 ? -17.315 -9.342  46.619 1.00 19.29 ?  364  ILE A CB   1 
ATOM   5470  C CG1  . ILE A 1 398 ? -17.158 -8.612  47.953 1.00 24.15 ?  364  ILE A CG1  1 
ATOM   5471  C CG2  . ILE A 1 398 ? -16.123 -10.240 46.347 1.00 19.94 ?  364  ILE A CG2  1 
ATOM   5472  C CD1  . ILE A 1 398 ? -17.301 -9.508  49.165 1.00 29.12 ?  364  ILE A CD1  1 
ATOM   5473  H H    . ILE A 1 398 ? -19.409 -8.105  45.771 1.00 20.55 ?  364  ILE A H    1 
ATOM   5474  H HA   . ILE A 1 398 ? -16.740 -7.681  45.542 1.00 19.52 ?  364  ILE A HA   1 
ATOM   5475  H HB   . ILE A 1 398 ? -18.106 -9.902  46.659 1.00 23.14 ?  364  ILE A HB   1 
ATOM   5476  H HG12 . ILE A 1 398 ? -16.277 -8.209  47.986 1.00 28.98 ?  364  ILE A HG12 1 
ATOM   5477  H HG13 . ILE A 1 398 ? -17.840 -7.924  48.013 1.00 28.98 ?  364  ILE A HG13 1 
ATOM   5478  H HG21 . ILE A 1 398 ? -15.939 -10.770 47.138 1.00 23.93 ?  364  ILE A HG21 1 
ATOM   5479  H HG22 . ILE A 1 398 ? -16.330 -10.823 45.600 1.00 23.93 ?  364  ILE A HG22 1 
ATOM   5480  H HG23 . ILE A 1 398 ? -15.354 -9.688  46.132 1.00 23.93 ?  364  ILE A HG23 1 
ATOM   5481  H HD11 . ILE A 1 398 ? -17.258 -8.963  49.967 1.00 34.94 ?  364  ILE A HD11 1 
ATOM   5482  H HD12 . ILE A 1 398 ? -18.156 -9.964  49.121 1.00 34.94 ?  364  ILE A HD12 1 
ATOM   5483  H HD13 . ILE A 1 398 ? -16.580 -10.156 49.165 1.00 34.94 ?  364  ILE A HD13 1 
ATOM   5484  N N    . TYR A 1 399 ? -16.334 -8.770  43.405 1.00 16.51 ?  365  TYR A N    1 
ATOM   5485  C CA   . TYR A 1 399 ? -16.122 -9.378  42.100 1.00 14.30 ?  365  TYR A CA   1 
ATOM   5486  C C    . TYR A 1 399 ? -14.821 -10.164 42.121 1.00 14.08 ?  365  TYR A C    1 
ATOM   5487  O O    . TYR A 1 399 ? -13.844 -9.734  42.735 1.00 16.20 ?  365  TYR A O    1 
ATOM   5488  C CB   . TYR A 1 399 ? -15.973 -8.323  40.994 1.00 14.95 ?  365  TYR A CB   1 
ATOM   5489  C CG   . TYR A 1 399 ? -17.165 -7.452  40.751 1.00 14.86 ?  365  TYR A CG   1 
ATOM   5490  C CD1  . TYR A 1 399 ? -17.496 -6.438  41.636 1.00 15.77 ?  365  TYR A CD1  1 
ATOM   5491  C CD2  . TYR A 1 399 ? -17.939 -7.603  39.612 1.00 14.31 ?  365  TYR A CD2  1 
ATOM   5492  C CE1  . TYR A 1 399 ? -18.566 -5.625  41.406 1.00 17.00 ?  365  TYR A CE1  1 
ATOM   5493  C CE2  . TYR A 1 399 ? -19.012 -6.779  39.368 1.00 14.24 ?  365  TYR A CE2  1 
ATOM   5494  C CZ   . TYR A 1 399 ? -19.318 -5.790  40.270 1.00 16.71 ?  365  TYR A CZ   1 
ATOM   5495  O OH   . TYR A 1 399 ? -20.390 -4.957  40.048 1.00 20.91 ?  365  TYR A OH   1 
ATOM   5496  H H    . TYR A 1 399 ? -15.682 -8.271  43.661 1.00 19.81 ?  365  TYR A H    1 
ATOM   5497  H HA   . TYR A 1 399 ? -16.879 -9.954  41.908 1.00 17.16 ?  365  TYR A HA   1 
ATOM   5498  H HB2  . TYR A 1 399 ? -15.235 -7.739  41.230 1.00 17.94 ?  365  TYR A HB2  1 
ATOM   5499  H HB3  . TYR A 1 399 ? -15.779 -8.782  40.162 1.00 17.94 ?  365  TYR A HB3  1 
ATOM   5500  H HD1  . TYR A 1 399 ? -16.981 -6.311  42.399 1.00 18.92 ?  365  TYR A HD1  1 
ATOM   5501  H HD2  . TYR A 1 399 ? -17.729 -8.274  39.003 1.00 17.17 ?  365  TYR A HD2  1 
ATOM   5502  H HE1  . TYR A 1 399 ? -18.786 -4.960  42.018 1.00 20.40 ?  365  TYR A HE1  1 
ATOM   5503  H HE2  . TYR A 1 399 ? -19.525 -6.890  38.601 1.00 17.09 ?  365  TYR A HE2  1 
ATOM   5504  H HH   . TYR A 1 399 ? -20.723 -5.112  39.293 1.00 25.10 ?  365  TYR A HH   1 
ATOM   5505  N N    . THR A 1 400 ? -14.791 -11.301 41.418 1.00 14.68 ?  366  THR A N    1 
ATOM   5506  C CA   . THR A 1 400 ? -13.558 -12.044 41.212 1.00 13.90 ?  366  THR A CA   1 
ATOM   5507  C C    . THR A 1 400 ? -13.380 -12.349 39.730 1.00 12.88 ?  366  THR A C    1 
ATOM   5508  O O    . THR A 1 400 ? -14.352 -12.427 38.973 1.00 13.78 ?  366  THR A O    1 
ATOM   5509  C CB   . THR A 1 400 ? -13.536 -13.367 42.020 1.00 15.72 ?  366  THR A CB   1 
ATOM   5510  O OG1  . THR A 1 400 ? -14.620 -14.189 41.588 1.00 17.64 ?  366  THR A OG1  1 
ATOM   5511  C CG2  . THR A 1 400 ? -13.664 -13.077 43.503 1.00 19.71 ?  366  THR A CG2  1 
ATOM   5512  H H    . THR A 1 400 ? -15.481 -11.660 41.051 1.00 17.61 ?  366  THR A H    1 
ATOM   5513  H HA   . THR A 1 400 ? -12.810 -11.499 41.504 1.00 16.67 ?  366  THR A HA   1 
ATOM   5514  H HB   . THR A 1 400 ? -12.699 -13.836 41.878 1.00 18.86 ?  366  THR A HB   1 
ATOM   5515  H HG1  . THR A 1 400 ? -14.533 -14.965 41.898 1.00 21.16 ?  366  THR A HG1  1 
ATOM   5516  H HG21 . THR A 1 400 ? -13.720 -13.908 44.000 1.00 23.65 ?  366  THR A HG21 1 
ATOM   5517  H HG22 . THR A 1 400 ? -12.892 -12.578 43.812 1.00 23.65 ?  366  THR A HG22 1 
ATOM   5518  H HG23 . THR A 1 400 ? -14.464 -12.555 43.671 1.00 23.65 ?  366  THR A HG23 1 
ATOM   5519  N N    . ARG A 1 401 ? -12.129 -12.528 39.319 1.00 13.97 ?  367  ARG A N    1 
ATOM   5520  C CA   . ARG A 1 401 ? -11.886 -12.971 37.956 1.00 12.71 ?  367  ARG A CA   1 
ATOM   5521  C C    . ARG A 1 401 ? -10.537 -13.659 37.895 1.00 12.47 ?  367  ARG A C    1 
ATOM   5522  O O    . ARG A 1 401 ? -9.585  -13.237 38.557 1.00 13.12 ?  367  ARG A O    1 
ATOM   5523  C CB   . ARG A 1 401 ? -11.941 -11.816 36.946 1.00 12.76 ?  367  ARG A CB   1 
ATOM   5524  C CG   . ARG A 1 401 ? -12.103 -12.307 35.522 1.00 11.96 ?  367  ARG A CG   1 
ATOM   5525  C CD   . ARG A 1 401 ? -12.314 -11.147 34.555 1.00 11.29 ?  367  ARG A CD   1 
ATOM   5526  N NE   . ARG A 1 401 ? -12.564 -11.614 33.204 1.00 12.71 ?  367  ARG A NE   1 
ATOM   5527  C CZ   . ARG A 1 401 ? -12.654 -10.813 32.154 1.00 11.70 ?  367  ARG A CZ   1 
ATOM   5528  N NH1  . ARG A 1 401 ? -12.468 -9.512  32.272 1.00 10.61 ?  367  ARG A NH1  1 
ATOM   5529  N NH2  . ARG A 1 401 ? -12.974 -11.323 30.969 1.00 11.19 ?  367  ARG A NH2  1 
ATOM   5530  H H    . ARG A 1 401 ? -11.426 -12.404 39.799 1.00 16.76 ?  367  ARG A H    1 
ATOM   5531  H HA   . ARG A 1 401 ? -12.573 -13.611 37.710 1.00 15.25 ?  367  ARG A HA   1 
ATOM   5532  H HB2  . ARG A 1 401 ? -12.697 -11.246 37.157 1.00 15.32 ?  367  ARG A HB2  1 
ATOM   5533  H HB3  . ARG A 1 401 ? -11.117 -11.308 36.999 1.00 15.32 ?  367  ARG A HB3  1 
ATOM   5534  H HG2  . ARG A 1 401 ? -11.303 -12.786 35.255 1.00 14.35 ?  367  ARG A HG2  1 
ATOM   5535  H HG3  . ARG A 1 401 ? -12.874 -12.893 35.470 1.00 14.35 ?  367  ARG A HG3  1 
ATOM   5536  H HD2  . ARG A 1 401 ? -13.079 -10.625 34.843 1.00 13.55 ?  367  ARG A HD2  1 
ATOM   5537  H HD3  . ARG A 1 401 ? -11.519 -10.592 34.542 1.00 13.55 ?  367  ARG A HD3  1 
ATOM   5538  H HE   . ARG A 1 401 ? -12.659 -12.460 33.078 1.00 15.25 ?  367  ARG A HE   1 
ATOM   5539  H HH11 . ARG A 1 401 ? -12.285 -9.172  33.040 1.00 12.73 ?  367  ARG A HH11 1 
ATOM   5540  H HH12 . ARG A 1 401 ? -12.530 -9.005  31.580 1.00 12.73 ?  367  ARG A HH12 1 
ATOM   5541  H HH21 . ARG A 1 401 ? -13.120 -12.167 30.889 1.00 13.43 ?  367  ARG A HH21 1 
ATOM   5542  H HH22 . ARG A 1 401 ? -13.034 -10.810 30.282 1.00 13.43 ?  367  ARG A HH22 1 
ATOM   5543  N N    . LYS A 1 402 ? -10.468 -14.729 37.112 1.00 13.77 ?  368  LYS A N    1 
ATOM   5544  C CA   . LYS A 1 402 ? -9.230  -15.459 36.908 1.00 12.97 ?  368  LYS A CA   1 
ATOM   5545  C C    . LYS A 1 402 ? -8.663  -15.252 35.511 1.00 13.49 ?  368  LYS A C    1 
ATOM   5546  O O    . LYS A 1 402 ? -9.387  -15.325 34.509 1.00 13.13 ?  368  LYS A O    1 
ATOM   5547  C CB   . LYS A 1 402 ? -9.445  -16.958 37.159 1.00 16.59 ?  368  LYS A CB   1 
ATOM   5548  C CG   . LYS A 1 402 ? -10.014 -17.237 38.551 1.00 21.89 ?  368  LYS A CG   1 
ATOM   5549  C CD   . LYS A 1 402 ? -10.139 -18.729 38.851 1.00 31.73 ?  368  LYS A CD   1 
ATOM   5550  C CE   . LYS A 1 402 ? -8.782  -19.376 39.072 1.00 41.29 ?  368  LYS A CE   1 
ATOM   5551  N NZ   . LYS A 1 402 ? -8.396  -19.350 40.515 1.00 39.57 ?  368  LYS A NZ   1 
ATOM   5552  H H    . LYS A 1 402 ? -11.138 -15.055 36.682 1.00 16.52 ?  368  LYS A H    1 
ATOM   5553  H HA   . LYS A 1 402 ? -8.569  -15.114 37.529 1.00 15.56 ?  368  LYS A HA   1 
ATOM   5554  H HB2  . LYS A 1 402 ? -10.069 -17.303 36.502 1.00 19.91 ?  368  LYS A HB2  1 
ATOM   5555  H HB3  . LYS A 1 402 ? -8.594  -17.418 37.083 1.00 19.91 ?  368  LYS A HB3  1 
ATOM   5556  H HG2  . LYS A 1 402 ? -9.427  -16.846 39.217 1.00 26.27 ?  368  LYS A HG2  1 
ATOM   5557  H HG3  . LYS A 1 402 ? -10.898 -16.844 38.616 1.00 26.27 ?  368  LYS A HG3  1 
ATOM   5558  H HD2  . LYS A 1 402 ? -10.668 -18.850 39.655 1.00 38.08 ?  368  LYS A HD2  1 
ATOM   5559  H HD3  . LYS A 1 402 ? -10.568 -19.171 38.102 1.00 38.08 ?  368  LYS A HD3  1 
ATOM   5560  H HE2  . LYS A 1 402 ? -8.814  -20.300 38.780 1.00 49.55 ?  368  LYS A HE2  1 
ATOM   5561  H HE3  . LYS A 1 402 ? -8.109  -18.892 38.567 1.00 49.55 ?  368  LYS A HE3  1 
ATOM   5562  H HZ1  . LYS A 1 402 ? -7.590  -19.713 40.622 1.00 47.48 ?  368  LYS A HZ1  1 
ATOM   5563  H HZ2  . LYS A 1 402 ? -8.375  -18.510 40.810 1.00 47.48 ?  368  LYS A HZ2  1 
ATOM   5564  H HZ3  . LYS A 1 402 ? -8.986  -19.811 40.996 1.00 47.48 ?  368  LYS A HZ3  1 
ATOM   5565  N N    . PHE A 1 403 ? -7.357  -15.023 35.469 1.00 11.59 ?  369  PHE A N    1 
ATOM   5566  C CA   . PHE A 1 403 ? -6.541  -14.934 34.271 1.00 12.23 ?  369  PHE A CA   1 
ATOM   5567  C C    . PHE A 1 403 ? -5.474  -16.019 34.360 1.00 13.77 ?  369  PHE A C    1 
ATOM   5568  O O    . PHE A 1 403 ? -5.217  -16.574 35.435 1.00 14.23 ?  369  PHE A O    1 
ATOM   5569  C CB   . PHE A 1 403 ? -5.883  -13.548 34.144 1.00 11.94 ?  369  PHE A CB   1 
ATOM   5570  C CG   . PHE A 1 403 ? -6.857  -12.412 33.996 1.00 11.71 ?  369  PHE A CG   1 
ATOM   5571  C CD1  . PHE A 1 403 ? -7.551  -11.919 35.089 1.00 11.69 ?  369  PHE A CD1  1 
ATOM   5572  C CD2  . PHE A 1 403 ? -7.057  -11.833 32.755 1.00 10.94 ?  369  PHE A CD2  1 
ATOM   5573  C CE1  . PHE A 1 403 ? -8.430  -10.872 34.948 1.00 12.80 ?  369  PHE A CE1  1 
ATOM   5574  C CE2  . PHE A 1 403 ? -7.937  -10.760 32.609 1.00 11.75 ?  369  PHE A CE2  1 
ATOM   5575  C CZ   . PHE A 1 403 ? -8.624  -10.294 33.710 1.00 11.68 ?  369  PHE A CZ   1 
ATOM   5576  H H    . PHE A 1 403 ? -6.886  -14.906 36.179 1.00 13.91 ?  369  PHE A H    1 
ATOM   5577  H HA   . PHE A 1 403 ? -7.079  -15.071 33.475 1.00 14.67 ?  369  PHE A HA   1 
ATOM   5578  H HB2  . PHE A 1 403 ? -5.356  -13.381 34.941 1.00 14.32 ?  369  PHE A HB2  1 
ATOM   5579  H HB3  . PHE A 1 403 ? -5.310  -13.548 33.361 1.00 14.32 ?  369  PHE A HB3  1 
ATOM   5580  H HD1  . PHE A 1 403 ? -7.420  -12.301 35.926 1.00 14.02 ?  369  PHE A HD1  1 
ATOM   5581  H HD2  . PHE A 1 403 ? -6.602  -12.162 32.013 1.00 13.13 ?  369  PHE A HD2  1 
ATOM   5582  H HE1  . PHE A 1 403 ? -8.895  -10.553 35.688 1.00 15.36 ?  369  PHE A HE1  1 
ATOM   5583  H HE2  . PHE A 1 403 ? -8.059  -10.363 31.777 1.00 14.10 ?  369  PHE A HE2  1 
ATOM   5584  H HZ   . PHE A 1 403 ? -9.220  -9.586  33.618 1.00 14.02 ?  369  PHE A HZ   1 
ATOM   5585  N N    . GLU A 1 404 ? -4.835  -16.305 33.224 1.00 12.45 ?  370  GLU A N    1 
ATOM   5586  C CA   . GLU A 1 404 ? -3.858  -17.393 33.194 1.00 14.25 ?  370  GLU A CA   1 
ATOM   5587  C C    . GLU A 1 404 ? -2.780  -17.207 34.258 1.00 16.28 ?  370  GLU A C    1 
ATOM   5588  O O    . GLU A 1 404 ? -2.357  -18.176 34.893 1.00 16.02 ?  370  GLU A O    1 
ATOM   5589  C CB   . GLU A 1 404 ? -3.268  -17.533 31.794 1.00 14.19 ?  370  GLU A CB   1 
ATOM   5590  C CG   . GLU A 1 404 ? -4.279  -18.154 30.847 1.00 17.44 ?  370  GLU A CG   1 
ATOM   5591  C CD   . GLU A 1 404 ? -3.981  -18.004 29.373 1.00 29.61 ?  370  GLU A CD   1 
ATOM   5592  O OE1  . GLU A 1 404 ? -3.098  -17.196 28.974 1.00 28.32 ?  370  GLU A OE1  1 
ATOM   5593  O OE2  . GLU A 1 404 ? -4.696  -18.681 28.597 1.00 23.42 ?  370  GLU A OE2  1 
ATOM   5594  H H    . GLU A 1 404 ? -4.946  -15.895 32.476 1.00 14.94 ?  370  GLU A H    1 
ATOM   5595  H HA   . GLU A 1 404 ? -4.308  -18.228 33.396 1.00 17.10 ?  370  GLU A HA   1 
ATOM   5596  H HB2  . GLU A 1 404 ? -3.025  -16.657 31.455 1.00 17.03 ?  370  GLU A HB2  1 
ATOM   5597  H HB3  . GLU A 1 404 ? -2.485  -18.104 31.828 1.00 17.03 ?  370  GLU A HB3  1 
ATOM   5598  H HG2  . GLU A 1 404 ? -4.327  -19.105 31.034 1.00 20.93 ?  370  GLU A HG2  1 
ATOM   5599  H HG3  . GLU A 1 404 ? -5.142  -17.740 31.008 1.00 20.93 ?  370  GLU A HG3  1 
ATOM   5600  N N    . ASN A 1 405 ? -2.353  -15.967 34.514 1.00 13.14 ?  371  ASN A N    1 
ATOM   5601  C CA   . ASN A 1 405 ? -1.270  -15.712 35.458 1.00 13.90 ?  371  ASN A CA   1 
ATOM   5602  C C    . ASN A 1 405 ? -1.660  -14.756 36.583 1.00 13.01 ?  371  ASN A C    1 
ATOM   5603  O O    . ASN A 1 405 ? -0.779  -14.181 37.232 1.00 14.65 ?  371  ASN A O    1 
ATOM   5604  C CB   . ASN A 1 405 ? -0.033  -15.186 34.730 1.00 15.17 ?  371  ASN A CB   1 
ATOM   5605  C CG   . ASN A 1 405 ? 0.438   -16.107 33.632 1.00 19.96 ?  371  ASN A CG   1 
ATOM   5606  O OD1  . ASN A 1 405 ? 0.223   -15.852 32.445 1.00 22.68 ?  371  ASN A OD1  1 
ATOM   5607  N ND2  . ASN A 1 405 ? 1.067   -17.198 34.024 1.00 29.65 ?  371  ASN A ND2  1 
ATOM   5608  H H    . ASN A 1 405 ? -2.678  -15.258 34.151 1.00 15.77 ?  371  ASN A H    1 
ATOM   5609  H HA   . ASN A 1 405 ? -1.045  -16.559 35.874 1.00 16.68 ?  371  ASN A HA   1 
ATOM   5610  H HB2  . ASN A 1 405 ? -0.244  -14.327 34.331 1.00 18.21 ?  371  ASN A HB2  1 
ATOM   5611  H HB3  . ASN A 1 405 ? 0.691   -15.086 35.368 1.00 18.21 ?  371  ASN A HB3  1 
ATOM   5612  H HD21 . ASN A 1 405 ? 1.187   -17.348 34.863 1.00 35.58 ?  371  ASN A HD21 1 
ATOM   5613  H HD22 . ASN A 1 405 ? 1.358   -17.760 33.442 1.00 35.58 ?  371  ASN A HD22 1 
ATOM   5614  N N    . LEU A 1 406 ? -2.948  -14.599 36.865 1.00 11.95 ?  372  LEU A N    1 
ATOM   5615  C CA   . LEU A 1 406 ? -3.381  -13.644 37.877 1.00 12.05 ?  372  LEU A CA   1 
ATOM   5616  C C    . LEU A 1 406 ? -4.783  -13.985 38.361 1.00 12.93 ?  372  LEU A C    1 
ATOM   5617  O O    . LEU A 1 406 ? -5.665  -14.278 37.553 1.00 13.98 ?  372  LEU A O    1 
ATOM   5618  C CB   . LEU A 1 406 ? -3.398  -12.224 37.271 1.00 13.86 ?  372  LEU A CB   1 
ATOM   5619  C CG   . LEU A 1 406 ? -4.038  -11.114 38.113 1.00 12.01 ?  372  LEU A CG   1 
ATOM   5620  C CD1  . LEU A 1 406 ? -3.228  -10.854 39.382 1.00 14.28 ?  372  LEU A CD1  1 
ATOM   5621  C CD2  . LEU A 1 406 ? -4.176  -9.849  37.256 1.00 13.08 ?  372  LEU A CD2  1 
ATOM   5622  H H    . LEU A 1 406 ? -3.588  -15.031 36.486 1.00 14.34 ?  372  LEU A H    1 
ATOM   5623  H HA   . LEU A 1 406 ? -2.783  -13.693 38.639 1.00 14.46 ?  372  LEU A HA   1 
ATOM   5624  H HB2  . LEU A 1 406 ? -2.480  -11.960 37.106 1.00 16.64 ?  372  LEU A HB2  1 
ATOM   5625  H HB3  . LEU A 1 406 ? -3.888  -12.263 36.435 1.00 16.64 ?  372  LEU A HB3  1 
ATOM   5626  H HG   . LEU A 1 406 ? -4.923  -11.385 38.403 1.00 14.41 ?  372  LEU A HG   1 
ATOM   5627  H HD11 . LEU A 1 406 ? -3.767  -10.335 40.000 1.00 17.14 ?  372  LEU A HD11 1 
ATOM   5628  H HD12 . LEU A 1 406 ? -2.989  -11.704 39.784 1.00 17.14 ?  372  LEU A HD12 1 
ATOM   5629  H HD13 . LEU A 1 406 ? -2.425  -10.362 39.149 1.00 17.14 ?  372  LEU A HD13 1 
ATOM   5630  H HD21 . LEU A 1 406 ? -4.566  -9.143  37.795 1.00 15.69 ?  372  LEU A HD21 1 
ATOM   5631  H HD22 . LEU A 1 406 ? -3.297  -9.581  36.945 1.00 15.69 ?  372  LEU A HD22 1 
ATOM   5632  H HD23 . LEU A 1 406 ? -4.750  -10.042 36.498 1.00 15.69 ?  372  LEU A HD23 1 
ATOM   5633  N N    . ASP A 1 407 ? -4.999  -13.883 39.674 1.00 13.33 ?  373  ASP A N    1 
ATOM   5634  C CA   . ASP A 1 407 ? -6.326  -13.930 40.274 1.00 13.45 ?  373  ASP A CA   1 
ATOM   5635  C C    . ASP A 1 407 ? -6.674  -12.553 40.828 1.00 14.20 ?  373  ASP A C    1 
ATOM   5636  O O    . ASP A 1 407 ? -5.868  -11.951 41.542 1.00 16.14 ?  373  ASP A O    1 
ATOM   5637  C CB   . ASP A 1 407 ? -6.395  -14.972 41.407 1.00 15.01 ?  373  ASP A CB   1 
ATOM   5638  C CG   . ASP A 1 407 ? -6.231  -16.393 40.911 1.00 21.96 ?  373  ASP A CG   1 
ATOM   5639  O OD1  . ASP A 1 407 ? -6.575  -16.684 39.752 1.00 24.77 ?  373  ASP A OD1  1 
ATOM   5640  O OD2  . ASP A 1 407 ? -5.741  -17.222 41.703 1.00 29.65 ?  373  ASP A OD2  1 
ATOM   5641  H H    . ASP A 1 407 ? -4.371  -13.783 40.252 1.00 15.99 ?  373  ASP A H    1 
ATOM   5642  H HA   . ASP A 1 407 ? -6.973  -14.174 39.594 1.00 16.14 ?  373  ASP A HA   1 
ATOM   5643  H HB2  . ASP A 1 407 ? -5.685  -14.793 42.044 1.00 18.01 ?  373  ASP A HB2  1 
ATOM   5644  H HB3  . ASP A 1 407 ? -7.258  -14.905 41.845 1.00 18.01 ?  373  ASP A HB3  1 
ATOM   5645  N N    . VAL A 1 408 ? -7.872  -12.076 40.518 1.00 13.57 ?  374  VAL A N    1 
ATOM   5646  C CA   . VAL A 1 408 ? -8.345  -10.756 40.930 1.00 13.88 ?  374  VAL A CA   1 
ATOM   5647  C C    . VAL A 1 408 ? -9.482  -10.929 41.928 1.00 13.95 ?  374  VAL A C    1 
ATOM   5648  O O    . VAL A 1 408 ? -10.425 -11.684 41.680 1.00 14.67 ?  374  VAL A O    1 
ATOM   5649  C CB   . VAL A 1 408 ? -8.825  -9.950  39.704 1.00 13.10 ?  374  VAL A CB   1 
ATOM   5650  C CG1  . VAL A 1 408 ? -9.361  -8.588  40.140 1.00 14.78 ?  374  VAL A CG1  1 
ATOM   5651  C CG2  . VAL A 1 408 ? -7.720  -9.798  38.684 1.00 12.98 ?  374  VAL A CG2  1 
ATOM   5652  H H    . VAL A 1 408 ? -8.450  -12.512 40.054 1.00 16.29 ?  374  VAL A H    1 
ATOM   5653  H HA   . VAL A 1 408 ? -7.626  -10.279 41.373 1.00 16.66 ?  374  VAL A HA   1 
ATOM   5654  H HB   . VAL A 1 408 ? -9.547  -10.437 39.277 1.00 15.72 ?  374  VAL A HB   1 
ATOM   5655  H HG11 . VAL A 1 408 ? -9.450  -8.019  39.359 1.00 17.73 ?  374  VAL A HG11 1 
ATOM   5656  H HG12 . VAL A 1 408 ? -10.226 -8.709  40.562 1.00 17.73 ?  374  VAL A HG12 1 
ATOM   5657  H HG13 . VAL A 1 408 ? -8.739  -8.190  40.769 1.00 17.73 ?  374  VAL A HG13 1 
ATOM   5658  H HG21 . VAL A 1 408 ? -8.062  -9.310  37.919 1.00 15.57 ?  374  VAL A HG21 1 
ATOM   5659  H HG22 . VAL A 1 408 ? -6.984  -9.310  39.086 1.00 15.57 ?  374  VAL A HG22 1 
ATOM   5660  H HG23 . VAL A 1 408 ? -7.421  -10.679 38.408 1.00 15.57 ?  374  VAL A HG23 1 
ATOM   5661  N N    . TRP A 1 409 ? -9.406  -10.205 43.046 1.00 14.47 ?  375  TRP A N    1 
ATOM   5662  C CA   . TRP A 1 409 ? -10.510 -10.060 43.987 1.00 16.44 ?  375  TRP A CA   1 
ATOM   5663  C C    . TRP A 1 409 ? -10.717 -8.566  44.204 1.00 14.58 ?  375  TRP A C    1 
ATOM   5664  O O    . TRP A 1 409 ? -9.739  -7.842  44.397 1.00 15.62 ?  375  TRP A O    1 
ATOM   5665  C CB   . TRP A 1 409 ? -10.168 -10.795 45.303 1.00 17.18 ?  375  TRP A CB   1 
ATOM   5666  C CG   . TRP A 1 409 ? -11.197 -10.662 46.388 1.00 15.57 ?  375  TRP A CG   1 
ATOM   5667  C CD1  . TRP A 1 409 ? -12.239 -11.510 46.650 1.00 19.77 ?  375  TRP A CD1  1 
ATOM   5668  C CD2  . TRP A 1 409 ? -11.280 -9.618  47.362 1.00 18.74 ?  375  TRP A CD2  1 
ATOM   5669  N NE1  . TRP A 1 409 ? -12.963 -11.052 47.730 1.00 22.18 ?  375  TRP A NE1  1 
ATOM   5670  C CE2  . TRP A 1 409 ? -12.395 -9.894  48.183 1.00 21.25 ?  375  TRP A CE2  1 
ATOM   5671  C CE3  . TRP A 1 409 ? -10.515 -8.480  47.623 1.00 21.35 ?  375  TRP A CE3  1 
ATOM   5672  C CZ2  . TRP A 1 409 ? -12.766 -9.065  49.241 1.00 22.53 ?  375  TRP A CZ2  1 
ATOM   5673  C CZ3  . TRP A 1 409 ? -10.888 -7.662  48.679 1.00 22.97 ?  375  TRP A CZ3  1 
ATOM   5674  C CH2  . TRP A 1 409 ? -12.000 -7.960  49.468 1.00 20.88 ?  375  TRP A CH2  1 
ATOM   5675  H H    . TRP A 1 409 ? -8.701  -9.776  43.287 1.00 17.36 ?  375  TRP A H    1 
ATOM   5676  H HA   . TRP A 1 409 ? -11.339 -10.432 43.650 1.00 19.73 ?  375  TRP A HA   1 
ATOM   5677  H HB2  . TRP A 1 409 ? -10.069 -11.741 45.110 1.00 20.62 ?  375  TRP A HB2  1 
ATOM   5678  H HB3  . TRP A 1 409 ? -9.334  -10.438 45.647 1.00 20.62 ?  375  TRP A HB3  1 
ATOM   5679  H HD1  . TRP A 1 409 ? -12.431 -12.283 46.169 1.00 23.72 ?  375  TRP A HD1  1 
ATOM   5680  H HE1  . TRP A 1 409 ? -13.658 -11.432 48.064 1.00 26.61 ?  375  TRP A HE1  1 
ATOM   5681  H HE3  . TRP A 1 409 ? -9.774  -8.274  47.101 1.00 25.62 ?  375  TRP A HE3  1 
ATOM   5682  H HZ2  . TRP A 1 409 ? -13.506 -9.258  49.770 1.00 27.03 ?  375  TRP A HZ2  1 
ATOM   5683  H HZ3  . TRP A 1 409 ? -10.386 -6.901  48.866 1.00 27.57 ?  375  TRP A HZ3  1 
ATOM   5684  H HH2  . TRP A 1 409 ? -12.225 -7.389  50.167 1.00 25.06 ?  375  TRP A HH2  1 
ATOM   5685  N N    . LEU A 1 410 ? -11.976 -8.125  44.155 1.00 15.18 ?  376  LEU A N    1 
ATOM   5686  C CA   . LEU A 1 410 ? -12.345 -6.713  44.242 1.00 18.85 ?  376  LEU A CA   1 
ATOM   5687  C C    . LEU A 1 410 ? -13.546 -6.539  45.158 1.00 16.59 ?  376  LEU A C    1 
ATOM   5688  O O    . LEU A 1 410 ? -14.563 -7.214  44.982 1.00 17.44 ?  376  LEU A O    1 
ATOM   5689  C CB   . LEU A 1 410 ? -12.713 -6.200  42.834 1.00 17.86 ?  376  LEU A CB   1 
ATOM   5690  C CG   . LEU A 1 410 ? -13.353 -4.827  42.680 1.00 14.36 ?  376  LEU A CG   1 
ATOM   5691  C CD1  . LEU A 1 410 ? -12.391 -3.745  43.095 1.00 18.49 ?  376  LEU A CD1  1 
ATOM   5692  C CD2  . LEU A 1 410 ? -13.769 -4.608  41.232 1.00 17.62 ?  376  LEU A CD2  1 
ATOM   5693  H H    . LEU A 1 410 ? -12.657 -8.643  44.069 1.00 18.22 ?  376  LEU A H    1 
ATOM   5694  H HA   . LEU A 1 410 ? -11.609 -6.204  44.616 1.00 22.62 ?  376  LEU A HA   1 
ATOM   5695  H HB2  . LEU A 1 410 ? -11.896 -6.180  42.311 1.00 21.43 ?  376  LEU A HB2  1 
ATOM   5696  H HB3  . LEU A 1 410 ? -13.337 -6.836  42.449 1.00 21.43 ?  376  LEU A HB3  1 
ATOM   5697  H HG   . LEU A 1 410 ? -14.138 -4.779  43.248 1.00 17.24 ?  376  LEU A HG   1 
ATOM   5698  H HD11 . LEU A 1 410 ? -12.816 -2.881  42.975 1.00 22.19 ?  376  LEU A HD11 1 
ATOM   5699  H HD12 . LEU A 1 410 ? -12.156 -3.872  44.028 1.00 22.19 ?  376  LEU A HD12 1 
ATOM   5700  H HD13 . LEU A 1 410 ? -11.595 -3.801  42.543 1.00 22.19 ?  376  LEU A HD13 1 
ATOM   5701  H HD21 . LEU A 1 410 ? -14.164 -3.726  41.147 1.00 21.15 ?  376  LEU A HD21 1 
ATOM   5702  H HD22 . LEU A 1 410 ? -12.986 -4.676  40.665 1.00 21.15 ?  376  LEU A HD22 1 
ATOM   5703  H HD23 . LEU A 1 410 ? -14.417 -5.286  40.984 1.00 21.15 ?  376  LEU A HD23 1 
ATOM   5704  N N    . ASN A 1 411 ? -13.460 -5.590  46.092 1.00 15.75 ?  377  ASN A N    1 
ATOM   5705  C CA   . ASN A 1 411 ? -14.596 -5.215  46.932 1.00 18.15 ?  377  ASN A CA   1 
ATOM   5706  C C    . ASN A 1 411 ? -14.866 -3.724  46.762 1.00 16.22 ?  377  ASN A C    1 
ATOM   5707  O O    . ASN A 1 411 ? -14.086 -2.887  47.231 1.00 17.85 ?  377  ASN A O    1 
ATOM   5708  C CB   . ASN A 1 411 ? -14.332 -5.583  48.394 1.00 19.80 ?  377  ASN A CB   1 
ATOM   5709  C CG   . ASN A 1 411 ? -15.538 -5.350  49.285 1.00 24.42 ?  377  ASN A CG   1 
ATOM   5710  O OD1  . ASN A 1 411 ? -16.452 -4.619  48.938 1.00 21.09 ?  377  ASN A OD1  1 
ATOM   5711  N ND2  . ASN A 1 411 ? -15.540 -5.988  50.449 1.00 29.50 ?  377  ASN A ND2  1 
ATOM   5712  H H    . ASN A 1 411 ? -12.744 -5.144  46.259 1.00 18.90 ?  377  ASN A H    1 
ATOM   5713  H HA   . ASN A 1 411 ? -15.390 -5.688  46.637 1.00 21.78 ?  377  ASN A HA   1 
ATOM   5714  H HB2  . ASN A 1 411 ? -14.098 -6.523  48.446 1.00 23.77 ?  377  ASN A HB2  1 
ATOM   5715  H HB3  . ASN A 1 411 ? -13.602 -5.040  48.730 1.00 23.77 ?  377  ASN A HB3  1 
ATOM   5716  H HD21 . ASN A 1 411 ? -16.200 -5.890  50.992 1.00 35.40 ?  377  ASN A HD21 1 
ATOM   5717  H HD22 . ASN A 1 411 ? -14.881 -6.498  50.661 1.00 35.40 ?  377  ASN A HD22 1 
ATOM   5718  N N    . LEU A 1 412 ? -15.968 -3.392  46.083 1.00 16.37 ?  378  LEU A N    1 
ATOM   5719  C CA   . LEU A 1 412 ? -16.268 -1.985  45.830 1.00 15.64 ?  378  LEU A CA   1 
ATOM   5720  C C    . LEU A 1 412 ? -16.657 -1.245  47.106 1.00 21.67 ?  378  LEU A C    1 
ATOM   5721  O O    . LEU A 1 412 ? -16.439 -0.033  47.206 1.00 22.27 ?  378  LEU A O    1 
ATOM   5722  C CB   . LEU A 1 412 ? -17.397 -1.840  44.813 1.00 16.96 ?  378  LEU A CB   1 
ATOM   5723  C CG   . LEU A 1 412 ? -17.193 -2.406  43.410 1.00 14.80 ?  378  LEU A CG   1 
ATOM   5724  C CD1  . LEU A 1 412 ? -18.457 -2.226  42.587 1.00 16.57 ?  378  LEU A CD1  1 
ATOM   5725  C CD2  . LEU A 1 412 ? -16.023 -1.735  42.707 1.00 16.61 ?  378  LEU A CD2  1 
ATOM   5726  H H    . LEU A 1 412 ? -16.542 -3.949  45.766 1.00 19.64 ?  378  LEU A H    1 
ATOM   5727  H HA   . LEU A 1 412 ? -15.467 -1.581  45.461 1.00 18.77 ?  378  LEU A HA   1 
ATOM   5728  H HB2  . LEU A 1 412 ? -18.178 -2.284  45.179 1.00 20.35 ?  378  LEU A HB2  1 
ATOM   5729  H HB3  . LEU A 1 412 ? -17.574 -0.892  44.706 1.00 20.35 ?  378  LEU A HB3  1 
ATOM   5730  H HG   . LEU A 1 412 ? -16.993 -3.352  43.486 1.00 17.76 ?  378  LEU A HG   1 
ATOM   5731  H HD11 . LEU A 1 412 ? -18.294 -2.543  41.685 1.00 19.89 ?  378  LEU A HD11 1 
ATOM   5732  H HD12 . LEU A 1 412 ? -19.174 -2.737  42.993 1.00 19.89 ?  378  LEU A HD12 1 
ATOM   5733  H HD13 . LEU A 1 412 ? -18.691 -1.285  42.569 1.00 19.89 ?  378  LEU A HD13 1 
ATOM   5734  H HD21 . LEU A 1 412 ? -15.970 -2.064  41.796 1.00 19.93 ?  378  LEU A HD21 1 
ATOM   5735  H HD22 . LEU A 1 412 ? -16.164 -0.775  42.705 1.00 19.93 ?  378  LEU A HD22 1 
ATOM   5736  H HD23 . LEU A 1 412 ? -15.205 -1.947  43.183 1.00 19.93 ?  378  LEU A HD23 1 
ATOM   5737  N N    . GLU A 1 413 ? -17.260 -1.939  48.073 1.00 20.88 ?  379  GLU A N    1 
ATOM   5738  C CA   . GLU A 1 413 ? -17.695 -1.278  49.304 1.00 26.25 ?  379  GLU A CA   1 
ATOM   5739  C C    . GLU A 1 413 ? -16.508 -0.740  50.096 1.00 23.32 ?  379  GLU A C    1 
ATOM   5740  O O    . GLU A 1 413 ? -16.508 0.417   50.532 1.00 27.02 ?  379  GLU A O    1 
ATOM   5741  C CB   . GLU A 1 413 ? -18.496 -2.260  50.159 1.00 28.41 ?  379  GLU A CB   1 
ATOM   5742  C CG   . GLU A 1 413 ? -19.572 -1.621  51.011 1.00 40.11 ?  379  GLU A CG   1 
ATOM   5743  C CD   . GLU A 1 413 ? -20.840 -2.444  51.038 1.00 41.50 ?  379  GLU A CD   1 
ATOM   5744  O OE1  . GLU A 1 413 ? -21.934 -1.850  50.922 1.00 49.79 ?  379  GLU A OE1  1 
ATOM   5745  O OE2  . GLU A 1 413 ? -20.740 -3.683  51.167 1.00 45.74 ?  379  GLU A OE2  1 
ATOM   5746  H H    . GLU A 1 413 ? -17.426 -2.782  48.042 1.00 25.06 ?  379  GLU A H    1 
ATOM   5747  H HA   . GLU A 1 413 ? -18.265 -0.529  49.069 1.00 31.50 ?  379  GLU A HA   1 
ATOM   5748  H HB2  . GLU A 1 413 ? -18.930 -2.898  49.571 1.00 34.10 ?  379  GLU A HB2  1 
ATOM   5749  H HB3  . GLU A 1 413 ? -17.885 -2.719  50.756 1.00 34.10 ?  379  GLU A HB3  1 
ATOM   5750  H HG2  . GLU A 1 413 ? -19.248 -1.534  51.921 1.00 48.13 ?  379  GLU A HG2  1 
ATOM   5751  H HG3  . GLU A 1 413 ? -19.787 -0.746  50.651 1.00 48.13 ?  379  GLU A HG3  1 
ATOM   5752  N N    . THR A 1 414 ? -15.494 -1.573  50.309 1.00 20.65 ?  380  THR A N    1 
ATOM   5753  C CA   . THR A 1 414 ? -14.301 -1.172  51.041 1.00 22.99 ?  380  THR A CA   1 
ATOM   5754  C C    . THR A 1 414 ? -13.259 -0.505  50.157 1.00 20.44 ?  380  THR A C    1 
ATOM   5755  O O    . THR A 1 414 ? -12.244 -0.019  50.671 1.00 22.91 ?  380  THR A O    1 
ATOM   5756  C CB   . THR A 1 414 ? -13.690 -2.405  51.702 1.00 23.43 ?  380  THR A CB   1 
ATOM   5757  O OG1  . THR A 1 414 ? -13.318 -3.345  50.683 1.00 22.09 ?  380  THR A OG1  1 
ATOM   5758  C CG2  . THR A 1 414 ? -14.695 -3.048  52.653 1.00 30.60 ?  380  THR A CG2  1 
ATOM   5759  H H    . THR A 1 414 ? -15.474 -2.388  50.035 1.00 24.78 ?  380  THR A H    1 
ATOM   5760  H HA   . THR A 1 414 ? -14.543 -0.537  51.732 1.00 27.58 ?  380  THR A HA   1 
ATOM   5761  H HB   . THR A 1 414 ? -12.906 -2.155  52.216 1.00 28.12 ?  380  THR A HB   1 
ATOM   5762  H HG1  . THR A 1 414 ? -12.975 -4.027  51.032 1.00 26.51 ?  380  THR A HG1  1 
ATOM   5763  H HG21 . THR A 1 414 ? -14.299 -3.825  53.078 1.00 36.72 ?  380  THR A HG21 1 
ATOM   5764  H HG22 . THR A 1 414 ? -14.956 -2.413  53.338 1.00 36.72 ?  380  THR A HG22 1 
ATOM   5765  H HG23 . THR A 1 414 ? -15.485 -3.325  52.163 1.00 36.72 ?  380  THR A HG23 1 
ATOM   5766  N N    . GLN A 1 415 ? -13.489 -0.458  48.842 1.00 19.76 ?  381  GLN A N    1 
ATOM   5767  C CA   . GLN A 1 415 ? -12.529 0.114   47.903 1.00 20.99 ?  381  GLN A CA   1 
ATOM   5768  C C    . GLN A 1 415 ? -11.164 -0.559  48.042 1.00 17.98 ?  381  GLN A C    1 
ATOM   5769  O O    . GLN A 1 415 ? -10.117 0.091   48.091 1.00 19.88 ?  381  GLN A O    1 
ATOM   5770  C CB   . GLN A 1 415 ? -12.436 1.638   48.056 1.00 20.52 ?  381  GLN A CB   1 
ATOM   5771  C CG   . GLN A 1 415 ? -13.730 2.363   47.666 1.00 20.63 ?  381  GLN A CG   1 
ATOM   5772  C CD   . GLN A 1 415 ? -13.558 3.859   47.389 1.00 25.57 ?  381  GLN A CD   1 
ATOM   5773  O OE1  . GLN A 1 415 ? -12.484 4.328   46.998 1.00 32.02 ?  381  GLN A OE1  1 
ATOM   5774  N NE2  . GLN A 1 415 ? -14.627 4.607   47.588 1.00 36.43 ?  381  GLN A NE2  1 
ATOM   5775  H H    . GLN A 1 415 ? -14.203 -0.756  48.468 1.00 23.72 ?  381  GLN A H    1 
ATOM   5776  H HA   . GLN A 1 415 ? -12.840 -0.059  47.001 1.00 25.18 ?  381  GLN A HA   1 
ATOM   5777  H HB2  . GLN A 1 415 ? -12.242 1.849   48.982 1.00 24.62 ?  381  GLN A HB2  1 
ATOM   5778  H HB3  . GLN A 1 415 ? -11.725 1.968   47.484 1.00 24.62 ?  381  GLN A HB3  1 
ATOM   5779  H HG2  . GLN A 1 415 ? -14.084 1.955   46.861 1.00 24.75 ?  381  GLN A HG2  1 
ATOM   5780  H HG3  . GLN A 1 415 ? -14.367 2.272   48.392 1.00 24.75 ?  381  GLN A HG3  1 
ATOM   5781  H HE21 . GLN A 1 415 ? -15.360 4.247   47.856 1.00 43.72 ?  381  GLN A HE21 1 
ATOM   5782  H HE22 . GLN A 1 415 ? -14.591 5.455   47.448 1.00 43.72 ?  381  GLN A HE22 1 
ATOM   5783  N N    . THR A 1 416 ? -11.184 -1.891  48.105 1.00 19.54 ?  382  THR A N    1 
ATOM   5784  C CA   . THR A 1 416 ? -9.969  -2.677  48.222 1.00 17.39 ?  382  THR A CA   1 
ATOM   5785  C C    . THR A 1 416 ? -9.966  -3.787  47.180 1.00 16.99 ?  382  THR A C    1 
ATOM   5786  O O    . THR A 1 416 ? -11.015 -4.211  46.688 1.00 17.82 ?  382  THR A O    1 
ATOM   5787  C CB   . THR A 1 416 ? -9.832  -3.308  49.626 1.00 21.01 ?  382  THR A CB   1 
ATOM   5788  O OG1  . THR A 1 416 ? -10.996 -4.093  49.902 1.00 24.97 ?  382  THR A OG1  1 
ATOM   5789  C CG2  . THR A 1 416 ? -9.659  -2.231  50.689 1.00 22.58 ?  382  THR A CG2  1 
ATOM   5790  H H    . THR A 1 416 ? -11.903 -2.363  48.081 1.00 23.45 ?  382  THR A H    1 
ATOM   5791  H HA   . THR A 1 416 ? -9.208  -2.097  48.060 1.00 20.87 ?  382  THR A HA   1 
ATOM   5792  H HB   . THR A 1 416 ? -9.047  -3.877  49.657 1.00 25.21 ?  382  THR A HB   1 
ATOM   5793  H HG1  . THR A 1 416 ? -10.929 -4.450  50.659 1.00 29.97 ?  382  THR A HG1  1 
ATOM   5794  H HG21 . THR A 1 416 ? -9.492  -2.641  51.552 1.00 27.09 ?  382  THR A HG21 1 
ATOM   5795  H HG22 . THR A 1 416 ? -8.909  -1.659  50.463 1.00 27.09 ?  382  THR A HG22 1 
ATOM   5796  H HG23 . THR A 1 416 ? -10.462 -1.690  50.748 1.00 27.09 ?  382  THR A HG23 1 
ATOM   5797  N N    . ALA A 1 417 ? -8.765  -4.247  46.847 1.00 16.43 ?  383  ALA A N    1 
ATOM   5798  C CA   . ALA A 1 417 ? -8.609  -5.364  45.924 1.00 16.33 ?  383  ALA A CA   1 
ATOM   5799  C C    . ALA A 1 417 ? -7.331  -6.121  46.253 1.00 17.86 ?  383  ALA A C    1 
ATOM   5800  O O    . ALA A 1 417 ? -6.416  -5.585  46.881 1.00 22.63 ?  383  ALA A O    1 
ATOM   5801  C CB   . ALA A 1 417 ? -8.512  -4.887  44.465 1.00 16.22 ?  383  ALA A CB   1 
ATOM   5802  H H    . ALA A 1 417 ? -8.023  -3.928  47.142 1.00 19.71 ?  383  ALA A H    1 
ATOM   5803  H HA   . ALA A 1 417 ? -9.373  -5.951  46.032 1.00 19.59 ?  383  ALA A HA   1 
ATOM   5804  H HB1  . ALA A 1 417 ? -8.472  -5.660  43.882 1.00 19.47 ?  383  ALA A HB1  1 
ATOM   5805  H HB2  . ALA A 1 417 ? -9.295  -4.353  44.255 1.00 19.47 ?  383  ALA A HB2  1 
ATOM   5806  H HB3  . ALA A 1 417 ? -7.710  -4.352  44.361 1.00 19.47 ?  383  ALA A HB3  1 
ATOM   5807  N N    . THR A 1 418 ? -7.260  -7.370  45.800 1.00 17.57 ?  384  THR A N    1 
ATOM   5808  C CA   . THR A 1 418 ? -6.010  -8.111  45.804 1.00 19.08 ?  384  THR A CA   1 
ATOM   5809  C C    . THR A 1 418 ? -5.735  -8.621  44.399 1.00 15.95 ?  384  THR A C    1 
ATOM   5810  O O    . THR A 1 418 ? -6.653  -9.069  43.703 1.00 19.90 ?  384  THR A O    1 
ATOM   5811  C CB   . THR A 1 418 ? -6.021  -9.288  46.780 1.00 21.47 ?  384  THR A CB   1 
ATOM   5812  O OG1  . THR A 1 418 ? -7.007  -10.235 46.377 1.00 25.35 ?  384  THR A OG1  1 
ATOM   5813  C CG2  . THR A 1 418 ? -6.317  -8.804  48.198 1.00 20.48 ?  384  THR A CG2  1 
ATOM   5814  H H    . THR A 1 418 ? -7.928  -7.809  45.484 1.00 21.09 ?  384  THR A H    1 
ATOM   5815  H HA   . THR A 1 418 ? -5.295  -7.515  46.078 1.00 22.89 ?  384  THR A HA   1 
ATOM   5816  H HB   . THR A 1 418 ? -5.151  -9.716  46.782 1.00 25.77 ?  384  THR A HB   1 
ATOM   5817  H HG1  . THR A 1 418 ? -7.007  -10.891 46.903 1.00 30.42 ?  384  THR A HG1  1 
ATOM   5818  H HG21 . THR A 1 418 ? -6.264  -9.547  48.820 1.00 24.57 ?  384  THR A HG21 1 
ATOM   5819  H HG22 . THR A 1 418 ? -5.673  -8.128  48.459 1.00 24.57 ?  384  THR A HG22 1 
ATOM   5820  H HG23 . THR A 1 418 ? -7.208  -8.423  48.240 1.00 24.57 ?  384  THR A HG23 1 
ATOM   5821  N N    . LEU A 1 419 ? -4.491  -8.492  43.975 1.00 17.18 ?  385  LEU A N    1 
ATOM   5822  C CA   . LEU A 1 419 ? -3.995  -9.053  42.725 1.00 16.78 ?  385  LEU A CA   1 
ATOM   5823  C C    . LEU A 1 419 ? -2.986  -10.123 43.121 1.00 21.13 ?  385  LEU A C    1 
ATOM   5824  O O    . LEU A 1 419 ? -1.904  -9.803  43.627 1.00 18.05 ?  385  LEU A O    1 
ATOM   5825  C CB   . LEU A 1 419 ? -3.328  -7.977  41.872 1.00 15.90 ?  385  LEU A CB   1 
ATOM   5826  C CG   . LEU A 1 419 ? -4.203  -6.794  41.434 1.00 15.25 ?  385  LEU A CG   1 
ATOM   5827  C CD1  . LEU A 1 419 ? -3.429  -5.863  40.500 1.00 15.04 ?  385  LEU A CD1  1 
ATOM   5828  C CD2  . LEU A 1 419 ? -5.497  -7.230  40.746 1.00 15.97 ?  385  LEU A CD2  1 
ATOM   5829  H H    . LEU A 1 419 ? -3.886  -8.065  44.412 1.00 20.62 ?  385  LEU A H    1 
ATOM   5830  H HA   . LEU A 1 419 ? -4.718  -9.440  42.208 1.00 20.13 ?  385  LEU A HA   1 
ATOM   5831  H HB2  . LEU A 1 419 ? -2.588  -7.609  42.380 1.00 19.08 ?  385  LEU A HB2  1 
ATOM   5832  H HB3  . LEU A 1 419 ? -2.997  -8.399  41.063 1.00 19.08 ?  385  LEU A HB3  1 
ATOM   5833  H HG   . LEU A 1 419 ? -4.449  -6.317  42.242 1.00 18.30 ?  385  LEU A HG   1 
ATOM   5834  H HD11 . LEU A 1 419 ? -4.002  -5.123  40.245 1.00 18.05 ?  385  LEU A HD11 1 
ATOM   5835  H HD12 . LEU A 1 419 ? -2.645  -5.530  40.965 1.00 18.05 ?  385  LEU A HD12 1 
ATOM   5836  H HD13 . LEU A 1 419 ? -3.160  -6.360  39.712 1.00 18.05 ?  385  LEU A HD13 1 
ATOM   5837  H HD21 . LEU A 1 419 ? -6.013  -6.442  40.516 1.00 19.17 ?  385  LEU A HD21 1 
ATOM   5838  H HD22 . LEU A 1 419 ? -5.276  -7.727  39.943 1.00 19.17 ?  385  LEU A HD22 1 
ATOM   5839  H HD23 . LEU A 1 419 ? -6.003  -7.792  41.354 1.00 19.17 ?  385  LEU A HD23 1 
ATOM   5840  N N    . THR A 1 420 ? -3.342  -11.388 42.914 1.00 17.40 ?  386  THR A N    1 
ATOM   5841  C CA   . THR A 1 420 ? -2.464  -12.510 43.253 1.00 16.88 ?  386  THR A CA   1 
ATOM   5842  C C    . THR A 1 420 ? -1.824  -12.988 41.960 1.00 13.15 ?  386  THR A C    1 
ATOM   5843  O O    . THR A 1 420 ? -2.436  -13.733 41.187 1.00 15.54 ?  386  THR A O    1 
ATOM   5844  C CB   . THR A 1 420 ? -3.229  -13.628 43.943 1.00 18.31 ?  386  THR A CB   1 
ATOM   5845  O OG1  . THR A 1 420 ? -3.937  -13.097 45.063 1.00 21.21 ?  386  THR A OG1  1 
ATOM   5846  C CG2  . THR A 1 420 ? -2.251  -14.707 44.418 1.00 21.32 ?  386  THR A CG2  1 
ATOM   5847  H H    . THR A 1 420 ? -4.096  -11.627 42.575 1.00 20.88 ?  386  THR A H    1 
ATOM   5848  H HA   . THR A 1 420 ? -1.773  -12.205 43.862 1.00 20.26 ?  386  THR A HA   1 
ATOM   5849  H HB   . THR A 1 420 ? -3.862  -14.031 43.328 1.00 21.97 ?  386  THR A HB   1 
ATOM   5850  H HG1  . THR A 1 420 ? -4.611  -12.670 44.800 1.00 25.45 ?  386  THR A HG1  1 
ATOM   5851  H HG21 . THR A 1 420 ? -2.706  -15.334 45.001 1.00 25.59 ?  386  THR A HG21 1 
ATOM   5852  H HG22 . THR A 1 420 ? -1.893  -15.189 43.656 1.00 25.59 ?  386  THR A HG22 1 
ATOM   5853  H HG23 . THR A 1 420 ? -1.518  -14.299 44.905 1.00 25.59 ?  386  THR A HG23 1 
ATOM   5854  N N    . TRP A 1 421 ? -0.604  -12.541 41.716 1.00 15.56 ?  387  TRP A N    1 
ATOM   5855  C CA   . TRP A 1 421 ? 0.122   -12.889 40.506 1.00 16.13 ?  387  TRP A CA   1 
ATOM   5856  C C    . TRP A 1 421 ? 0.701   -14.292 40.628 1.00 18.09 ?  387  TRP A C    1 
ATOM   5857  O O    . TRP A 1 421 ? 1.235   -14.669 41.674 1.00 19.54 ?  387  TRP A O    1 
ATOM   5858  C CB   . TRP A 1 421 ? 1.247   -11.881 40.256 1.00 17.62 ?  387  TRP A CB   1 
ATOM   5859  C CG   . TRP A 1 421 ? 0.781   -10.443 40.133 1.00 15.52 ?  387  TRP A CG   1 
ATOM   5860  C CD1  . TRP A 1 421 ? 0.688   -9.538  41.139 1.00 17.36 ?  387  TRP A CD1  1 
ATOM   5861  C CD2  . TRP A 1 421 ? 0.321   -9.779  38.947 1.00 15.69 ?  387  TRP A CD2  1 
ATOM   5862  N NE1  . TRP A 1 421 ? 0.220   -8.334  40.655 1.00 16.77 ?  387  TRP A NE1  1 
ATOM   5863  C CE2  . TRP A 1 421 ? -0.018  -8.464  39.313 1.00 15.36 ?  387  TRP A CE2  1 
ATOM   5864  C CE3  . TRP A 1 421 ? 0.177   -10.165 37.612 1.00 15.62 ?  387  TRP A CE3  1 
ATOM   5865  C CZ2  . TRP A 1 421 ? -0.493  -7.536  38.393 1.00 15.62 ?  387  TRP A CZ2  1 
ATOM   5866  C CZ3  . TRP A 1 421 ? -0.297  -9.238  36.704 1.00 14.44 ?  387  TRP A CZ3  1 
ATOM   5867  C CH2  . TRP A 1 421 ? -0.626  -7.945  37.101 1.00 14.97 ?  387  TRP A CH2  1 
ATOM   5868  H H    . TRP A 1 421 ? -0.165  -12.024 42.245 1.00 18.67 ?  387  TRP A H    1 
ATOM   5869  H HA   . TRP A 1 421 ? -0.480  -12.868 39.745 1.00 19.36 ?  387  TRP A HA   1 
ATOM   5870  H HB2  . TRP A 1 421 ? 1.873   -11.925 40.996 1.00 21.14 ?  387  TRP A HB2  1 
ATOM   5871  H HB3  . TRP A 1 421 ? 1.695   -12.116 39.428 1.00 21.14 ?  387  TRP A HB3  1 
ATOM   5872  H HD1  . TRP A 1 421 ? 0.909   -9.704  42.027 1.00 20.83 ?  387  TRP A HD1  1 
ATOM   5873  H HE1  . TRP A 1 421 ? 0.098   -7.620  41.119 1.00 20.13 ?  387  TRP A HE1  1 
ATOM   5874  H HE3  . TRP A 1 421 ? 0.395   -11.027 37.341 1.00 18.75 ?  387  TRP A HE3  1 
ATOM   5875  H HZ2  . TRP A 1 421 ? -0.712  -6.670  38.651 1.00 18.74 ?  387  TRP A HZ2  1 
ATOM   5876  H HZ3  . TRP A 1 421 ? -0.397  -9.483  35.812 1.00 17.33 ?  387  TRP A HZ3  1 
ATOM   5877  H HH2  . TRP A 1 421 ? -0.945  -7.344  36.467 1.00 17.97 ?  387  TRP A HH2  1 
ATOM   5878  N N    . LYS A 1 422 ? 0.587   -15.063 39.553 1.00 17.78 ?  388  LYS A N    1 
ATOM   5879  C CA   . LYS A 1 422 ? 1.073   -16.439 39.515 1.00 20.64 ?  388  LYS A CA   1 
ATOM   5880  C C    . LYS A 1 422 ? 2.352   -16.442 38.698 1.00 25.25 ?  388  LYS A C    1 
ATOM   5881  O O    . LYS A 1 422 ? 2.360   -15.965 37.554 1.00 30.59 ?  388  LYS A O    1 
ATOM   5882  C CB   . LYS A 1 422 ? 0.049   -17.396 38.879 1.00 24.38 ?  388  LYS A CB   1 
ATOM   5883  C CG   . LYS A 1 422 ? -1.410  -17.250 39.328 1.00 30.82 ?  388  LYS A CG   1 
ATOM   5884  C CD   . LYS A 1 422 ? -2.403  -18.027 38.407 1.00 32.60 ?  388  LYS A CD   1 
ATOM   5885  C CE   . LYS A 1 422 ? -3.877  -17.867 38.864 1.00 38.02 ?  388  LYS A CE   1 
ATOM   5886  N NZ   . LYS A 1 422 ? -4.952  -17.999 37.787 1.00 35.25 ?  388  LYS A NZ   1 
ATOM   5887  H H    . LYS A 1 422 ? 0.223   -14.808 38.816 1.00 21.34 ?  388  LYS A H    1 
ATOM   5888  H HA   . LYS A 1 422 ? 1.226   -16.768 40.415 1.00 24.76 ?  388  LYS A HA   1 
ATOM   5889  H HB2  . LYS A 1 422 ? 0.065   -17.257 37.919 1.00 29.25 ?  388  LYS A HB2  1 
ATOM   5890  H HB3  . LYS A 1 422 ? 0.319   -18.305 39.087 1.00 29.25 ?  388  LYS A HB3  1 
ATOM   5891  H HG2  . LYS A 1 422 ? -1.501  -17.599 40.229 1.00 36.98 ?  388  LYS A HG2  1 
ATOM   5892  H HG3  . LYS A 1 422 ? -1.655  -16.312 39.309 1.00 36.98 ?  388  LYS A HG3  1 
ATOM   5893  H HD2  . LYS A 1 422 ? -2.329  -17.688 37.501 1.00 39.12 ?  388  LYS A HD2  1 
ATOM   5894  H HD3  . LYS A 1 422 ? -2.182  -18.972 38.426 1.00 39.12 ?  388  LYS A HD3  1 
ATOM   5895  H HE2  . LYS A 1 422 ? -4.061  -18.548 39.530 1.00 45.63 ?  388  LYS A HE2  1 
ATOM   5896  H HE3  . LYS A 1 422 ? -3.976  -16.985 39.255 1.00 45.63 ?  388  LYS A HE3  1 
ATOM   5897  H HZ1  . LYS A 1 422 ? -5.758  -17.877 38.144 1.00 42.30 ?  388  LYS A HZ1  1 
ATOM   5898  H HZ2  . LYS A 1 422 ? -4.822  -17.388 37.152 1.00 42.30 ?  388  LYS A HZ2  1 
ATOM   5899  H HZ3  . LYS A 1 422 ? -4.917  -18.809 37.420 1.00 42.30 ?  388  LYS A HZ3  1 
ATOM   5900  N N    . ILE B 1 57  ? 1.915   54.521  62.366 1.00 52.07 ?  23   ILE B N    1 
ATOM   5901  C CA   . ILE B 1 57  ? 0.659   54.067  61.784 1.00 43.45 ?  23   ILE B CA   1 
ATOM   5902  C C    . ILE B 1 57  ? -0.219  55.230  61.300 1.00 31.72 ?  23   ILE B C    1 
ATOM   5903  O O    . ILE B 1 57  ? -0.988  55.826  62.050 1.00 28.49 ?  23   ILE B O    1 
ATOM   5904  C CB   . ILE B 1 57  ? -0.121  53.173  62.756 1.00 46.18 ?  23   ILE B CB   1 
ATOM   5905  C CG1  . ILE B 1 57  ? 0.555   51.817  62.966 1.00 40.19 ?  23   ILE B CG1  1 
ATOM   5906  C CG2  . ILE B 1 57  ? -1.489  52.928  62.208 1.00 39.00 ?  23   ILE B CG2  1 
ATOM   5907  C CD1  . ILE B 1 57  ? 0.316   50.818  61.835 1.00 42.07 ?  23   ILE B CD1  1 
ATOM   5908  H H    . ILE B 1 57  ? 1.875   54.685  63.206 1.00 62.48 ?  23   ILE B H    1 
ATOM   5909  H HA   . ILE B 1 57  ? 0.889   53.542  61.001 1.00 52.14 ?  23   ILE B HA   1 
ATOM   5910  H HB   . ILE B 1 57  ? -0.152  53.636  63.607 1.00 55.42 ?  23   ILE B HB   1 
ATOM   5911  H HG12 . ILE B 1 57  ? 1.512   51.955  63.040 1.00 48.22 ?  23   ILE B HG12 1 
ATOM   5912  H HG13 . ILE B 1 57  ? 0.212   51.423  63.784 1.00 48.22 ?  23   ILE B HG13 1 
ATOM   5913  H HG21 . ILE B 1 57  ? -1.884  52.173  62.671 1.00 46.81 ?  23   ILE B HG21 1 
ATOM   5914  H HG22 . ILE B 1 57  ? -2.031  53.721  62.347 1.00 46.81 ?  23   ILE B HG22 1 
ATOM   5915  H HG23 . ILE B 1 57  ? -1.420  52.736  61.260 1.00 46.81 ?  23   ILE B HG23 1 
ATOM   5916  H HD11 . ILE B 1 57  ? 0.976   50.110  61.895 1.00 50.48 ?  23   ILE B HD11 1 
ATOM   5917  H HD12 . ILE B 1 57  ? -0.576  50.448  61.924 1.00 50.48 ?  23   ILE B HD12 1 
ATOM   5918  H HD13 . ILE B 1 57  ? 0.400   51.278  60.985 1.00 50.48 ?  23   ILE B HD13 1 
ATOM   5919  N N    . ASP B 1 58  ? -0.122  55.520  60.014 1.00 25.73 ?  24   ASP B N    1 
ATOM   5920  C CA   . ASP B 1 58  ? -0.906  56.566  59.373 1.00 24.79 ?  24   ASP B CA   1 
ATOM   5921  C C    . ASP B 1 58  ? -2.127  55.893  58.751 1.00 17.98 ?  24   ASP B C    1 
ATOM   5922  O O    . ASP B 1 58  ? -1.985  54.993  57.914 1.00 17.61 ?  24   ASP B O    1 
ATOM   5923  C CB   . ASP B 1 58  ? -0.001  57.277  58.368 1.00 24.14 ?  24   ASP B CB   1 
ATOM   5924  C CG   . ASP B 1 58  ? -0.745  58.103  57.346 1.00 20.75 ?  24   ASP B CG   1 
ATOM   5925  O OD1  . ASP B 1 58  ? -1.914  58.460  57.558 1.00 18.60 ?  24   ASP B OD1  1 
ATOM   5926  O OD2  . ASP B 1 58  ? -0.096  58.485  56.346 1.00 27.75 ?  24   ASP B OD2  1 
ATOM   5927  H H    . ASP B 1 58  ? 0.407   55.112  59.473 1.00 30.87 ?  24   ASP B H    1 
ATOM   5928  H HA   . ASP B 1 58  ? -1.246  57.237  59.985 1.00 29.75 ?  24   ASP B HA   1 
ATOM   5929  H HB2  . ASP B 1 58  ? 0.593   57.872  58.851 1.00 28.97 ?  24   ASP B HB2  1 
ATOM   5930  H HB3  . ASP B 1 58  ? 0.515   56.611  57.888 1.00 28.97 ?  24   ASP B HB3  1 
ATOM   5931  N N    . TYR B 1 59  ? -3.311  56.270  59.231 1.00 16.83 ?  25   TYR B N    1 
ATOM   5932  C CA   . TYR B 1 59  ? -4.577  55.711  58.765 1.00 13.63 ?  25   TYR B CA   1 
ATOM   5933  C C    . TYR B 1 59  ? -5.245  56.548  57.692 1.00 14.83 ?  25   TYR B C    1 
ATOM   5934  O O    . TYR B 1 59  ? -6.368  56.227  57.286 1.00 15.15 ?  25   TYR B O    1 
ATOM   5935  C CB   . TYR B 1 59  ? -5.579  55.529  59.921 1.00 17.95 ?  25   TYR B CB   1 
ATOM   5936  C CG   . TYR B 1 59  ? -5.150  54.536  60.962 1.00 17.30 ?  25   TYR B CG   1 
ATOM   5937  C CD1  . TYR B 1 59  ? -5.212  53.180  60.690 1.00 16.79 ?  25   TYR B CD1  1 
ATOM   5938  C CD2  . TYR B 1 59  ? -4.721  54.927  62.225 1.00 21.03 ?  25   TYR B CD2  1 
ATOM   5939  C CE1  . TYR B 1 59  ? -4.840  52.242  61.616 1.00 17.56 ?  25   TYR B CE1  1 
ATOM   5940  C CE2  . TYR B 1 59  ? -4.348  53.973  63.179 1.00 24.98 ?  25   TYR B CE2  1 
ATOM   5941  C CZ   . TYR B 1 59  ? -4.418  52.630  62.862 1.00 21.20 ?  25   TYR B CZ   1 
ATOM   5942  O OH   . TYR B 1 59  ? -4.043  51.655  63.773 1.00 21.15 ?  25   TYR B OH   1 
ATOM   5943  H H    . TYR B 1 59  ? -3.409  56.864  59.845 1.00 20.19 ?  25   TYR B H    1 
ATOM   5944  H HA   . TYR B 1 59  ? -4.375  54.835  58.402 1.00 16.35 ?  25   TYR B HA   1 
ATOM   5945  H HB2  . TYR B 1 59  ? -5.700  56.384  60.363 1.00 21.54 ?  25   TYR B HB2  1 
ATOM   5946  H HB3  . TYR B 1 59  ? -6.423  55.222  59.554 1.00 21.54 ?  25   TYR B HB3  1 
ATOM   5947  H HD1  . TYR B 1 59  ? -5.514  52.899  59.857 1.00 20.15 ?  25   TYR B HD1  1 
ATOM   5948  H HD2  . TYR B 1 59  ? -4.682  55.832  62.439 1.00 25.24 ?  25   TYR B HD2  1 
ATOM   5949  H HE1  . TYR B 1 59  ? -4.875  51.338  61.399 1.00 21.07 ?  25   TYR B HE1  1 
ATOM   5950  H HE2  . TYR B 1 59  ? -4.056  54.241  64.021 1.00 29.97 ?  25   TYR B HE2  1 
ATOM   5951  H HH   . TYR B 1 59  ? -3.766  52.014  64.480 1.00 25.38 ?  25   TYR B HH   1 
ATOM   5952  N N    . SER B 1 60  ? -4.599  57.623  57.239 1.00 15.63 ?  26   SER B N    1 
ATOM   5953  C CA   . SER B 1 60  ? -5.290  58.596  56.402 1.00 14.82 ?  26   SER B CA   1 
ATOM   5954  C C    . SER B 1 60  ? -5.746  58.025  55.071 1.00 16.60 ?  26   SER B C    1 
ATOM   5955  O O    . SER B 1 60  ? -6.685  58.557  54.477 1.00 16.31 ?  26   SER B O    1 
ATOM   5956  C CB   . SER B 1 60  ? -4.413  59.835  56.183 1.00 17.44 ?  26   SER B CB   1 
ATOM   5957  O OG   . SER B 1 60  ? -3.230  59.535  55.469 1.00 19.54 ?  26   SER B OG   1 
ATOM   5958  H H    . SER B 1 60  ? -3.774  57.808  57.400 1.00 18.75 ?  26   SER B H    1 
ATOM   5959  H HA   . SER B 1 60  ? -6.087  58.881  56.874 1.00 17.78 ?  26   SER B HA   1 
ATOM   5960  H HB2  . SER B 1 60  ? -4.921  60.490  55.680 1.00 20.92 ?  26   SER B HB2  1 
ATOM   5961  H HB3  . SER B 1 60  ? -4.168  60.198  57.049 1.00 20.92 ?  26   SER B HB3  1 
ATOM   5962  H HG   . SER B 1 60  ? -2.799  60.240  55.318 1.00 23.45 ?  26   SER B HG   1 
ATOM   5963  N N    . ASN B 1 61  ? -5.126  56.947  54.594 1.00 12.81 ?  27   ASN B N    1 
ATOM   5964  C CA   . ASN B 1 61  ? -5.479  56.359  53.309 1.00 13.68 ?  27   ASN B CA   1 
ATOM   5965  C C    . ASN B 1 61  ? -6.267  55.072  53.452 1.00 11.40 ?  27   ASN B C    1 
ATOM   5966  O O    . ASN B 1 61  ? -6.534  54.414  52.450 1.00 12.12 ?  27   ASN B O    1 
ATOM   5967  C CB   . ASN B 1 61  ? -4.215  56.156  52.481 1.00 11.64 ?  27   ASN B CB   1 
ATOM   5968  C CG   . ASN B 1 61  ? -3.410  57.413  52.386 1.00 16.45 ?  27   ASN B CG   1 
ATOM   5969  O OD1  . ASN B 1 61  ? -3.933  58.464  51.996 1.00 18.47 ?  27   ASN B OD1  1 
ATOM   5970  N ND2  . ASN B 1 61  ? -2.150  57.332  52.764 1.00 15.64 ?  27   ASN B ND2  1 
ATOM   5971  H H    . ASN B 1 61  ? -4.491  56.536  55.004 1.00 15.37 ?  27   ASN B H    1 
ATOM   5972  H HA   . ASN B 1 61  ? -6.049  56.972  52.819 1.00 16.41 ?  27   ASN B HA   1 
ATOM   5973  H HB2  . ASN B 1 61  ? -3.666  55.473  52.897 1.00 13.97 ?  27   ASN B HB2  1 
ATOM   5974  H HB3  . ASN B 1 61  ? -4.460  55.882  51.584 1.00 13.97 ?  27   ASN B HB3  1 
ATOM   5975  H HD21 . ASN B 1 61  ? -1.645  58.027  52.728 1.00 18.77 ?  27   ASN B HD21 1 
ATOM   5976  H HD22 . ASN B 1 61  ? -1.833  56.584  53.046 1.00 18.77 ?  27   ASN B HD22 1 
ATOM   5977  N N    . TYR B 1 62  ? -6.682  54.726  54.650 1.00 11.26 ?  28   TYR B N    1 
ATOM   5978  C CA   . TYR B 1 62  ? -7.359  53.457  54.866 1.00 10.54 ?  28   TYR B CA   1 
ATOM   5979  C C    . TYR B 1 62  ? -8.801  53.524  54.372 1.00 12.16 ?  28   TYR B C    1 
ATOM   5980  O O    . TYR B 1 62  ? -9.376  54.606  54.207 1.00 12.65 ?  28   TYR B O    1 
ATOM   5981  C CB   . TYR B 1 62  ? -7.363  53.118  56.352 1.00 11.98 ?  28   TYR B CB   1 
ATOM   5982  C CG   . TYR B 1 62  ? -6.182  52.316  56.879 1.00 10.97 ?  28   TYR B CG   1 
ATOM   5983  C CD1  . TYR B 1 62  ? -4.882  52.578  56.478 1.00 10.96 ?  28   TYR B CD1  1 
ATOM   5984  C CD2  . TYR B 1 62  ? -6.376  51.302  57.815 1.00 11.07 ?  28   TYR B CD2  1 
ATOM   5985  C CE1  . TYR B 1 62  ? -3.818  51.854  56.990 1.00 11.48 ?  28   TYR B CE1  1 
ATOM   5986  C CE2  . TYR B 1 62  ? -5.329  50.583  58.330 1.00 11.44 ?  28   TYR B CE2  1 
ATOM   5987  C CZ   . TYR B 1 62  ? -4.049  50.847  57.924 1.00 12.72 ?  28   TYR B CZ   1 
ATOM   5988  O OH   . TYR B 1 62  ? -2.997  50.116  58.454 1.00 12.76 ?  28   TYR B OH   1 
ATOM   5989  H H    . TYR B 1 62  ? -6.586  55.204  55.358 1.00 13.51 ?  28   TYR B H    1 
ATOM   5990  H HA   . TYR B 1 62  ? -6.893  52.759  54.381 1.00 12.65 ?  28   TYR B HA   1 
ATOM   5991  H HB2  . TYR B 1 62  ? -7.383  53.951  56.848 1.00 14.37 ?  28   TYR B HB2  1 
ATOM   5992  H HB3  . TYR B 1 62  ? -8.162  52.601  56.539 1.00 14.37 ?  28   TYR B HB3  1 
ATOM   5993  H HD1  . TYR B 1 62  ? -4.721  53.250  55.856 1.00 13.15 ?  28   TYR B HD1  1 
ATOM   5994  H HD2  . TYR B 1 62  ? -7.240  51.107  58.099 1.00 13.28 ?  28   TYR B HD2  1 
ATOM   5995  H HE1  . TYR B 1 62  ? -2.951  52.040  56.711 1.00 13.77 ?  28   TYR B HE1  1 
ATOM   5996  H HE2  . TYR B 1 62  ? -5.489  49.915  58.956 1.00 13.72 ?  28   TYR B HE2  1 
ATOM   5997  H HH   . TYR B 1 62  ? -3.267  49.647  59.096 1.00 15.31 ?  28   TYR B HH   1 
ATOM   5998  N N    . PRO B 1 63  ? -9.416  52.364  54.148 1.00 10.35 ?  29   PRO B N    1 
ATOM   5999  C CA   . PRO B 1 63  ? -10.817 52.328  53.740 1.00 10.48 ?  29   PRO B CA   1 
ATOM   6000  C C    . PRO B 1 63  ? -11.741 52.717  54.883 1.00 11.49 ?  29   PRO B C    1 
ATOM   6001  O O    . PRO B 1 63  ? -11.349 52.798  56.052 1.00 12.77 ?  29   PRO B O    1 
ATOM   6002  C CB   . PRO B 1 63  ? -11.044 50.861  53.338 1.00 9.89  ?  29   PRO B CB   1 
ATOM   6003  C CG   . PRO B 1 63  ? -9.795  50.145  53.633 1.00 14.05 ?  29   PRO B CG   1 
ATOM   6004  C CD   . PRO B 1 63  ? -8.875  51.022  54.404 1.00 10.53 ?  29   PRO B CD   1 
ATOM   6005  H HA   . PRO B 1 63  ? -10.962 52.910  52.978 1.00 12.58 ?  29   PRO B HA   1 
ATOM   6006  H HB2  . PRO B 1 63  ? -11.777 50.493  53.855 1.00 11.86 ?  29   PRO B HB2  1 
ATOM   6007  H HB3  . PRO B 1 63  ? -11.249 50.813  52.391 1.00 11.86 ?  29   PRO B HB3  1 
ATOM   6008  H HG2  . PRO B 1 63  ? -10.007 49.354  54.153 1.00 16.86 ?  29   PRO B HG2  1 
ATOM   6009  H HG3  . PRO B 1 63  ? -9.379  49.890  52.795 1.00 16.86 ?  29   PRO B HG3  1 
ATOM   6010  H HD2  . PRO B 1 63  ? -8.904  50.810  55.350 1.00 12.63 ?  29   PRO B HD2  1 
ATOM   6011  H HD3  . PRO B 1 63  ? -7.965  50.946  54.075 1.00 12.63 ?  29   PRO B HD3  1 
ATOM   6012  N N    . GLU B 1 64  ? -12.999 52.940  54.524 1.00 10.41 ?  30   GLU B N    1 
ATOM   6013  C CA   . GLU B 1 64  ? -14.037 53.071  55.532 1.00 9.61  ?  30   GLU B CA   1 
ATOM   6014  C C    . GLU B 1 64  ? -14.163 51.768  56.306 1.00 12.27 ?  30   GLU B C    1 
ATOM   6015  O O    . GLU B 1 64  ? -13.898 50.678  55.788 1.00 10.83 ?  30   GLU B O    1 
ATOM   6016  C CB   . GLU B 1 64  ? -15.379 53.389  54.872 1.00 11.88 ?  30   GLU B CB   1 
ATOM   6017  C CG   . GLU B 1 64  ? -15.373 54.683  54.041 1.00 13.33 ?  30   GLU B CG   1 
ATOM   6018  C CD   . GLU B 1 64  ? -14.975 55.924  54.801 1.00 20.73 ?  30   GLU B CD   1 
ATOM   6019  O OE1  . GLU B 1 64  ? -15.545 56.177  55.873 1.00 22.38 ?  30   GLU B OE1  1 
ATOM   6020  O OE2  . GLU B 1 64  ? -14.101 56.661  54.301 1.00 27.48 ?  30   GLU B OE2  1 
ATOM   6021  H H    . GLU B 1 64  ? -13.274 53.019  53.713 1.00 12.50 ?  30   GLU B H    1 
ATOM   6022  H HA   . GLU B 1 64  ? -13.813 53.792  56.141 1.00 11.54 ?  30   GLU B HA   1 
ATOM   6023  H HB2  . GLU B 1 64  ? -15.616 52.659  54.279 1.00 14.26 ?  30   GLU B HB2  1 
ATOM   6024  H HB3  . GLU B 1 64  ? -16.051 53.486  55.565 1.00 14.26 ?  30   GLU B HB3  1 
ATOM   6025  H HG2  . GLU B 1 64  ? -14.746 54.576  53.310 1.00 16.00 ?  30   GLU B HG2  1 
ATOM   6026  H HG3  . GLU B 1 64  ? -16.267 54.830  53.694 1.00 16.00 ?  30   GLU B HG3  1 
ATOM   6027  N N    . PHE B 1 65  ? -14.618 51.874  57.546 1.00 11.22 ?  31   PHE B N    1 
ATOM   6028  C CA   . PHE B 1 65  ? -14.853 50.706  58.371 1.00 10.80 ?  31   PHE B CA   1 
ATOM   6029  C C    . PHE B 1 65  ? -15.970 51.004  59.357 1.00 12.41 ?  31   PHE B C    1 
ATOM   6030  O O    . PHE B 1 65  ? -15.984 52.068  59.981 1.00 13.34 ?  31   PHE B O    1 
ATOM   6031  C CB   . PHE B 1 65  ? -13.619 50.284  59.164 1.00 12.18 ?  31   PHE B CB   1 
ATOM   6032  C CG   . PHE B 1 65  ? -13.866 49.068  59.999 1.00 10.35 ?  31   PHE B CG   1 
ATOM   6033  C CD1  . PHE B 1 65  ? -13.706 47.799  59.459 1.00 9.94  ?  31   PHE B CD1  1 
ATOM   6034  C CD2  . PHE B 1 65  ? -14.338 49.182  61.298 1.00 11.75 ?  31   PHE B CD2  1 
ATOM   6035  C CE1  . PHE B 1 65  ? -13.966 46.699  60.202 1.00 11.04 ?  31   PHE B CE1  1 
ATOM   6036  C CE2  . PHE B 1 65  ? -14.602 48.079  62.053 1.00 11.07 ?  31   PHE B CE2  1 
ATOM   6037  C CZ   . PHE B 1 65  ? -14.428 46.825  61.505 1.00 10.91 ?  31   PHE B CZ   1 
ATOM   6038  H H    . PHE B 1 65  ? -14.799 52.620  57.934 1.00 13.47 ?  31   PHE B H    1 
ATOM   6039  H HA   . PHE B 1 65  ? -15.113 49.978  57.786 1.00 12.96 ?  31   PHE B HA   1 
ATOM   6040  H HB2  . PHE B 1 65  ? -12.898 50.085  58.546 1.00 14.62 ?  31   PHE B HB2  1 
ATOM   6041  H HB3  . PHE B 1 65  ? -13.359 51.008  59.755 1.00 14.62 ?  31   PHE B HB3  1 
ATOM   6042  H HD1  . PHE B 1 65  ? -13.417 47.705  58.580 1.00 11.93 ?  31   PHE B HD1  1 
ATOM   6043  H HD2  . PHE B 1 65  ? -14.478 50.027  61.661 1.00 14.10 ?  31   PHE B HD2  1 
ATOM   6044  H HE1  . PHE B 1 65  ? -13.835 45.853  59.838 1.00 13.24 ?  31   PHE B HE1  1 
ATOM   6045  H HE2  . PHE B 1 65  ? -14.896 48.171  62.930 1.00 13.28 ?  31   PHE B HE2  1 
ATOM   6046  H HZ   . PHE B 1 65  ? -14.619 46.066  62.008 1.00 13.09 ?  31   PHE B HZ   1 
ATOM   6047  N N    . SER B 1 66  ? -16.880 50.052  59.513 1.00 12.27 ?  32   SER B N    1 
ATOM   6048  C CA   . SER B 1 66  ? -17.899 50.121  60.547 1.00 12.84 ?  32   SER B CA   1 
ATOM   6049  C C    . SER B 1 66  ? -18.127 48.727  61.114 1.00 13.45 ?  32   SER B C    1 
ATOM   6050  O O    . SER B 1 66  ? -18.153 47.744  60.367 1.00 12.89 ?  32   SER B O    1 
ATOM   6051  C CB   . SER B 1 66  ? -19.218 50.652  59.974 1.00 15.04 ?  32   SER B CB   1 
ATOM   6052  O OG   . SER B 1 66  ? -20.238 50.626  60.959 1.00 15.51 ?  32   SER B OG   1 
ATOM   6053  H H    . SER B 1 66  ? -16.927 49.345  59.024 1.00 14.73 ?  32   SER B H    1 
ATOM   6054  H HA   . SER B 1 66  ? -17.604 50.706  61.262 1.00 15.41 ?  32   SER B HA   1 
ATOM   6055  H HB2  . SER B 1 66  ? -19.088 51.566  59.677 1.00 18.05 ?  32   SER B HB2  1 
ATOM   6056  H HB3  . SER B 1 66  ? -19.486 50.095  59.227 1.00 18.05 ?  32   SER B HB3  1 
ATOM   6057  H HG   . SER B 1 66  ? -20.990 50.718  60.597 1.00 18.61 ?  32   SER B HG   1 
ATOM   6058  N N    . TRP B 1 67  ? -18.325 48.653  62.428 1.00 12.90 ?  33   TRP B N    1 
ATOM   6059  C CA   . TRP B 1 67  ? -18.784 47.435  63.079 1.00 12.01 ?  33   TRP B CA   1 
ATOM   6060  C C    . TRP B 1 67  ? -20.299 47.234  62.996 1.00 12.22 ?  33   TRP B C    1 
ATOM   6061  O O    . TRP B 1 67  ? -20.791 46.224  63.513 1.00 13.15 ?  33   TRP B O    1 
ATOM   6062  C CB   . TRP B 1 67  ? -18.411 47.441  64.565 1.00 12.64 ?  33   TRP B CB   1 
ATOM   6063  C CG   . TRP B 1 67  ? -16.944 47.276  64.890 1.00 12.36 ?  33   TRP B CG   1 
ATOM   6064  C CD1  . TRP B 1 67  ? -16.118 48.204  65.461 1.00 13.87 ?  33   TRP B CD1  1 
ATOM   6065  C CD2  . TRP B 1 67  ? -16.155 46.099  64.707 1.00 12.32 ?  33   TRP B CD2  1 
ATOM   6066  N NE1  . TRP B 1 67  ? -14.857 47.677  65.627 1.00 14.48 ?  33   TRP B NE1  1 
ATOM   6067  C CE2  . TRP B 1 67  ? -14.858 46.379  65.180 1.00 12.50 ?  33   TRP B CE2  1 
ATOM   6068  C CE3  . TRP B 1 67  ? -16.425 44.834  64.202 1.00 12.59 ?  33   TRP B CE3  1 
ATOM   6069  C CZ2  . TRP B 1 67  ? -13.836 45.440  65.142 1.00 13.73 ?  33   TRP B CZ2  1 
ATOM   6070  C CZ3  . TRP B 1 67  ? -15.414 43.898  64.171 1.00 12.69 ?  33   TRP B CZ3  1 
ATOM   6071  C CH2  . TRP B 1 67  ? -14.138 44.200  64.642 1.00 14.25 ?  33   TRP B CH2  1 
ATOM   6072  H H    . TRP B 1 67  ? -18.197 49.307  62.971 1.00 15.48 ?  33   TRP B H    1 
ATOM   6073  H HA   . TRP B 1 67  ? -18.336 46.696  62.639 1.00 14.41 ?  33   TRP B HA   1 
ATOM   6074  H HB2  . TRP B 1 67  ? -18.694 48.288  64.944 1.00 15.17 ?  33   TRP B HB2  1 
ATOM   6075  H HB3  . TRP B 1 67  ? -18.882 46.711  64.997 1.00 15.17 ?  33   TRP B HB3  1 
ATOM   6076  H HD1  . TRP B 1 67  ? -16.370 49.066  65.702 1.00 16.65 ?  33   TRP B HD1  1 
ATOM   6077  H HE1  . TRP B 1 67  ? -14.180 48.092  65.957 1.00 17.38 ?  33   TRP B HE1  1 
ATOM   6078  H HE3  . TRP B 1 67  ? -17.275 44.621  63.890 1.00 15.10 ?  33   TRP B HE3  1 
ATOM   6079  H HZ2  . TRP B 1 67  ? -12.981 45.644  65.445 1.00 16.47 ?  33   TRP B HZ2  1 
ATOM   6080  H HZ3  . TRP B 1 67  ? -15.586 43.050  63.830 1.00 15.23 ?  33   TRP B HZ3  1 
ATOM   6081  H HH2  . TRP B 1 67  ? -13.477 43.547  64.616 1.00 17.10 ?  33   TRP B HH2  1 
ATOM   6082  N N    . ASP B 1 68  ? -21.048 48.166  62.399 1.00 13.20 ?  34   ASP B N    1 
ATOM   6083  C CA   . ASP B 1 68  ? -22.509 48.095  62.487 1.00 12.54 ?  34   ASP B CA   1 
ATOM   6084  C C    . ASP B 1 68  ? -23.033 46.758  61.976 1.00 13.85 ?  34   ASP B C    1 
ATOM   6085  O O    . ASP B 1 68  ? -23.943 46.165  62.572 1.00 13.46 ?  34   ASP B O    1 
ATOM   6086  C CB   . ASP B 1 68  ? -23.165 49.231  61.697 1.00 15.69 ?  34   ASP B CB   1 
ATOM   6087  C CG   . ASP B 1 68  ? -23.035 50.596  62.361 1.00 16.79 ?  34   ASP B CG   1 
ATOM   6088  O OD1  . ASP B 1 68  ? -22.543 50.679  63.502 1.00 19.01 ?  34   ASP B OD1  1 
ATOM   6089  O OD2  . ASP B 1 68  ? -23.441 51.588  61.712 1.00 20.82 ?  34   ASP B OD2  1 
ATOM   6090  H H    . ASP B 1 68  ? -20.743 48.832  61.948 1.00 15.84 ?  34   ASP B H    1 
ATOM   6091  H HA   . ASP B 1 68  ? -22.750 48.195  63.421 1.00 15.04 ?  34   ASP B HA   1 
ATOM   6092  H HB2  . ASP B 1 68  ? -22.747 49.286  60.824 1.00 18.83 ?  34   ASP B HB2  1 
ATOM   6093  H HB3  . ASP B 1 68  ? -24.111 49.038  61.600 1.00 18.83 ?  34   ASP B HB3  1 
ATOM   6094  N N    . THR B 1 69  ? -22.504 46.291  60.845 1.00 11.75 ?  35   THR B N    1 
ATOM   6095  C CA   . THR B 1 69  ? -22.807 44.987  60.270 1.00 11.01 ?  35   THR B CA   1 
ATOM   6096  C C    . THR B 1 69  ? -21.487 44.409  59.772 1.00 11.32 ?  35   THR B C    1 
ATOM   6097  O O    . THR B 1 69  ? -20.448 45.083  59.793 1.00 10.69 ?  35   THR B O    1 
ATOM   6098  C CB   . THR B 1 69  ? -23.808 45.106  59.117 1.00 12.12 ?  35   THR B CB   1 
ATOM   6099  O OG1  . THR B 1 69  ? -23.254 45.916  58.074 1.00 13.33 ?  35   THR B OG1  1 
ATOM   6100  C CG2  . THR B 1 69  ? -25.134 45.734  59.599 1.00 15.00 ?  35   THR B CG2  1 
ATOM   6101  H H    . THR B 1 69  ? -21.941 46.735  60.371 1.00 14.10 ?  35   THR B H    1 
ATOM   6102  H HA   . THR B 1 69  ? -23.193 44.398  60.936 1.00 13.21 ?  35   THR B HA   1 
ATOM   6103  H HB   . THR B 1 69  ? -24.000 44.219  58.773 1.00 14.55 ?  35   THR B HB   1 
ATOM   6104  H HG1  . THR B 1 69  ? -22.745 45.454  57.592 1.00 16.00 ?  35   THR B HG1  1 
ATOM   6105  H HG21 . THR B 1 69  ? -25.767 45.776  58.865 1.00 18.00 ?  35   THR B HG21 1 
ATOM   6106  H HG22 . THR B 1 69  ? -25.515 45.199  60.313 1.00 18.00 ?  35   THR B HG22 1 
ATOM   6107  H HG23 . THR B 1 69  ? -24.975 46.632  59.930 1.00 18.00 ?  35   THR B HG23 1 
ATOM   6108  N N    . MET B 1 70  ? -21.523 43.142  59.327 1.00 10.12 ?  36   MET B N    1 
ATOM   6109  C CA   . MET B 1 70  ? -20.299 42.521  58.818 1.00 10.28 ?  36   MET B CA   1 
ATOM   6110  C C    . MET B 1 70  ? -19.439 43.370  57.923 1.00 8.62  ?  36   MET B C    1 
ATOM   6111  O O    . MET B 1 70  ? -19.930 43.831  56.887 1.00 10.24 ?  36   MET B O    1 
ATOM   6112  C CB   . MET B 1 70  ? -20.608 41.210  58.095 1.00 10.21 ?  36   MET B CB   1 
ATOM   6113  C CG   . MET B 1 70  ? -19.523 40.158  58.185 1.00 9.88  ?  36   MET B CG   1 
ATOM   6114  S SD   . MET B 1 70  ? -18.922 39.602  59.733 1.00 10.99 ?  36   MET B SD   1 
ATOM   6115  C CE   . MET B 1 70  ? -20.560 39.072  60.459 1.00 13.36 ?  36   MET B CE   1 
ATOM   6116  H H    . MET B 1 70  ? -22.222 42.642  59.312 1.00 12.14 ?  36   MET B H    1 
ATOM   6117  H HA   . MET B 1 70  ? -19.777 42.368  59.621 1.00 12.34 ?  36   MET B HA   1 
ATOM   6118  H HB2  . MET B 1 70  ? -21.414 40.830  58.478 1.00 12.26 ?  36   MET B HB2  1 
ATOM   6119  H HB3  . MET B 1 70  ? -20.747 41.403  57.155 1.00 12.26 ?  36   MET B HB3  1 
ATOM   6120  H HG2  . MET B 1 70  ? -19.858 39.367  57.734 1.00 11.86 ?  36   MET B HG2  1 
ATOM   6121  H HG3  . MET B 1 70  ? -18.751 40.507  57.713 1.00 11.86 ?  36   MET B HG3  1 
ATOM   6122  H HE1  . MET B 1 70  ? -20.410 38.712  61.348 1.00 16.03 ?  36   MET B HE1  1 
ATOM   6123  H HE2  . MET B 1 70  ? -21.147 39.843  60.509 1.00 16.03 ?  36   MET B HE2  1 
ATOM   6124  H HE3  . MET B 1 70  ? -20.953 38.393  59.889 1.00 16.03 ?  36   MET B HE3  1 
ATOM   6125  N N    . PRO B 1 71  ? -18.150 43.550  58.233 1.00 9.12  ?  37   PRO B N    1 
ATOM   6126  C CA   . PRO B 1 71  ? -17.251 44.271  57.316 1.00 8.95  ?  37   PRO B CA   1 
ATOM   6127  C C    . PRO B 1 71  ? -16.805 43.345  56.193 1.00 8.71  ?  37   PRO B C    1 
ATOM   6128  O O    . PRO B 1 71  ? -16.218 42.286  56.437 1.00 9.24  ?  37   PRO B O    1 
ATOM   6129  C CB   . PRO B 1 71  ? -16.081 44.685  58.219 1.00 9.74  ?  37   PRO B CB   1 
ATOM   6130  C CG   . PRO B 1 71  ? -16.054 43.645  59.306 1.00 10.68 ?  37   PRO B CG   1 
ATOM   6131  C CD   . PRO B 1 71  ? -17.514 43.326  59.547 1.00 9.49  ?  37   PRO B CD   1 
ATOM   6132  H HA   . PRO B 1 71  ? -17.674 45.063  56.948 1.00 10.74 ?  37   PRO B HA   1 
ATOM   6133  H HB2  . PRO B 1 71  ? -15.254 44.682  57.713 1.00 11.69 ?  37   PRO B HB2  1 
ATOM   6134  H HB3  . PRO B 1 71  ? -16.242 45.568  58.586 1.00 11.69 ?  37   PRO B HB3  1 
ATOM   6135  H HG2  . PRO B 1 71  ? -15.569 42.860  59.006 1.00 12.82 ?  37   PRO B HG2  1 
ATOM   6136  H HG3  . PRO B 1 71  ? -15.638 44.006  60.105 1.00 12.82 ?  37   PRO B HG3  1 
ATOM   6137  H HD2  . PRO B 1 71  ? -17.621 42.404  59.827 1.00 11.39 ?  37   PRO B HD2  1 
ATOM   6138  H HD3  . PRO B 1 71  ? -17.889 43.922  60.215 1.00 11.39 ?  37   PRO B HD3  1 
ATOM   6139  N N    . LEU B 1 72  ? -17.102 43.735  54.964 1.00 7.85  ?  38   LEU B N    1 
ATOM   6140  C CA   . LEU B 1 72  ? -16.962 42.838  53.824 1.00 7.88  ?  38   LEU B CA   1 
ATOM   6141  C C    . LEU B 1 72  ? -15.882 43.295  52.846 1.00 8.61  ?  38   LEU B C    1 
ATOM   6142  O O    . LEU B 1 72  ? -15.696 44.494  52.599 1.00 9.27  ?  38   LEU B O    1 
ATOM   6143  C CB   . LEU B 1 72  ? -18.276 42.755  53.049 1.00 9.31  ?  38   LEU B CB   1 
ATOM   6144  C CG   . LEU B 1 72  ? -19.458 42.219  53.860 1.00 8.71  ?  38   LEU B CG   1 
ATOM   6145  C CD1  . LEU B 1 72  ? -20.712 42.286  53.022 1.00 11.77 ?  38   LEU B CD1  1 
ATOM   6146  C CD2  . LEU B 1 72  ? -19.254 40.797  54.368 1.00 9.46  ?  38   LEU B CD2  1 
ATOM   6147  H H    . LEU B 1 72  ? -17.388 44.521  54.761 1.00 9.42  ?  38   LEU B H    1 
ATOM   6148  H HA   . LEU B 1 72  ? -16.704 41.968  54.168 1.00 9.45  ?  38   LEU B HA   1 
ATOM   6149  H HB2  . LEU B 1 72  ? -18.509 43.645  52.742 1.00 11.18 ?  38   LEU B HB2  1 
ATOM   6150  H HB3  . LEU B 1 72  ? -18.149 42.164  52.289 1.00 11.18 ?  38   LEU B HB3  1 
ATOM   6151  H HG   . LEU B 1 72  ? -19.546 42.777  54.649 1.00 10.45 ?  38   LEU B HG   1 
ATOM   6152  H HD11 . LEU B 1 72  ? -21.457 41.941  53.539 1.00 14.13 ?  38   LEU B HD11 1 
ATOM   6153  H HD12 . LEU B 1 72  ? -20.879 43.209  52.777 1.00 14.13 ?  38   LEU B HD12 1 
ATOM   6154  H HD13 . LEU B 1 72  ? -20.587 41.749  52.224 1.00 14.13 ?  38   LEU B HD13 1 
ATOM   6155  H HD21 . LEU B 1 72  ? -20.074 40.490  54.786 1.00 11.35 ?  38   LEU B HD21 1 
ATOM   6156  H HD22 . LEU B 1 72  ? -19.030 40.223  53.619 1.00 11.35 ?  38   LEU B HD22 1 
ATOM   6157  H HD23 . LEU B 1 72  ? -18.531 40.794  55.015 1.00 11.35 ?  38   LEU B HD23 1 
ATOM   6158  N N    . TYR B 1 73  ? -15.211 42.309  52.247 1.00 7.99  ?  39   TYR B N    1 
ATOM   6159  C CA   . TYR B 1 73  ? -14.194 42.483  51.217 1.00 7.34  ?  39   TYR B CA   1 
ATOM   6160  C C    . TYR B 1 73  ? -14.686 41.880  49.906 1.00 7.93  ?  39   TYR B C    1 
ATOM   6161  O O    . TYR B 1 73  ? -15.368 40.855  49.897 1.00 8.10  ?  39   TYR B O    1 
ATOM   6162  C CB   . TYR B 1 73  ? -12.939 41.706  51.641 1.00 7.42  ?  39   TYR B CB   1 
ATOM   6163  C CG   . TYR B 1 73  ? -11.774 41.642  50.667 1.00 7.74  ?  39   TYR B CG   1 
ATOM   6164  C CD1  . TYR B 1 73  ? -11.143 42.780  50.216 1.00 8.34  ?  39   TYR B CD1  1 
ATOM   6165  C CD2  . TYR B 1 73  ? -11.268 40.420  50.242 1.00 7.91  ?  39   TYR B CD2  1 
ATOM   6166  C CE1  . TYR B 1 73  ? -10.045 42.701  49.377 1.00 7.76  ?  39   TYR B CE1  1 
ATOM   6167  C CE2  . TYR B 1 73  ? -10.173 40.338  49.434 1.00 7.79  ?  39   TYR B CE2  1 
ATOM   6168  C CZ   . TYR B 1 73  ? -9.577  41.471  48.980 1.00 7.22  ?  39   TYR B CZ   1 
ATOM   6169  O OH   . TYR B 1 73  ? -8.477  41.410  48.154 1.00 7.55  ?  39   TYR B OH   1 
ATOM   6170  H H    . TYR B 1 73  ? -15.338 41.480  52.435 1.00 9.59  ?  39   TYR B H    1 
ATOM   6171  H HA   . TYR B 1 73  ? -13.997 43.423  51.082 1.00 8.81  ?  39   TYR B HA   1 
ATOM   6172  H HB2  . TYR B 1 73  ? -12.600 42.114  52.453 1.00 8.90  ?  39   TYR B HB2  1 
ATOM   6173  H HB3  . TYR B 1 73  ? -13.204 40.790  51.816 1.00 8.90  ?  39   TYR B HB3  1 
ATOM   6174  H HD1  . TYR B 1 73  ? -11.460 43.614  50.479 1.00 10.01 ?  39   TYR B HD1  1 
ATOM   6175  H HD2  . TYR B 1 73  ? -11.688 39.636  50.516 1.00 9.49  ?  39   TYR B HD2  1 
ATOM   6176  H HE1  . TYR B 1 73  ? -9.625  43.477  49.084 1.00 9.31  ?  39   TYR B HE1  1 
ATOM   6177  H HE2  . TYR B 1 73  ? -9.834  39.506  49.194 1.00 9.35  ?  39   TYR B HE2  1 
ATOM   6178  H HH   . TYR B 1 73  ? -8.028  40.722  48.324 1.00 9.06  ?  39   TYR B HH   1 
ATOM   6179  N N    . MET B 1 74  ? -14.304 42.491  48.785 1.00 8.47  ?  40   MET B N    1 
ATOM   6180  C CA   . MET B 1 74  ? -14.607 41.902  47.485 1.00 6.93  ?  40   MET B CA   1 
ATOM   6181  C C    . MET B 1 74  ? -13.304 41.783  46.691 1.00 7.47  ?  40   MET B C    1 
ATOM   6182  O O    . MET B 1 74  ? -12.421 42.634  46.784 1.00 7.53  ?  40   MET B O    1 
ATOM   6183  C CB   . MET B 1 74  ? -15.592 42.774  46.705 1.00 8.17  ?  40   MET B CB   1 
ATOM   6184  C CG   . MET B 1 74  ? -16.124 42.232  45.374 1.00 9.97  ?  40   MET B CG   1 
ATOM   6185  S SD   . MET B 1 74  ? -16.464 40.450  45.241 1.00 9.51  ?  40   MET B SD   1 
ATOM   6186  C CE   . MET B 1 74  ? -17.781 40.298  46.398 1.00 11.85 ?  40   MET B CE   1 
ATOM   6187  H H    . MET B 1 74  ? -13.876 43.236  48.754 1.00 10.16 ?  40   MET B H    1 
ATOM   6188  H HA   . MET B 1 74  ? -15.004 41.026  47.606 1.00 8.31  ?  40   MET B HA   1 
ATOM   6189  H HB2  . MET B 1 74  ? -16.364 42.929  47.272 1.00 9.80  ?  40   MET B HB2  1 
ATOM   6190  H HB3  . MET B 1 74  ? -15.151 43.615  46.507 1.00 9.80  ?  40   MET B HB3  1 
ATOM   6191  H HG2  . MET B 1 74  ? -16.959 42.687  45.184 1.00 11.97 ?  40   MET B HG2  1 
ATOM   6192  H HG3  . MET B 1 74  ? -15.469 42.439  44.689 1.00 11.97 ?  40   MET B HG3  1 
ATOM   6193  H HE1  . MET B 1 74  ? -18.070 39.372  46.427 1.00 14.22 ?  40   MET B HE1  1 
ATOM   6194  H HE2  . MET B 1 74  ? -17.466 40.573  47.273 1.00 14.22 ?  40   MET B HE2  1 
ATOM   6195  H HE3  . MET B 1 74  ? -18.516 40.865  46.117 1.00 14.22 ?  40   MET B HE3  1 
ATOM   6196  N N    . HIS B 1 75  ? -13.197 40.705  45.917 1.00 6.75  ?  41   HIS B N    1 
ATOM   6197  C CA   . HIS B 1 75  ? -11.971 40.317  45.222 1.00 6.99  ?  41   HIS B CA   1 
ATOM   6198  C C    . HIS B 1 75  ? -12.460 39.635  43.953 1.00 7.11  ?  41   HIS B C    1 
ATOM   6199  O O    . HIS B 1 75  ? -13.094 38.585  44.054 1.00 7.36  ?  41   HIS B O    1 
ATOM   6200  C CB   . HIS B 1 75  ? -11.172 39.378  46.112 1.00 6.60  ?  41   HIS B CB   1 
ATOM   6201  C CG   . HIS B 1 75  ? -9.800  39.076  45.610 1.00 6.94  ?  41   HIS B CG   1 
ATOM   6202  N ND1  . HIS B 1 75  ? -8.656  39.538  46.227 1.00 7.16  ?  41   HIS B ND1  1 
ATOM   6203  C CD2  . HIS B 1 75  ? -9.391  38.329  44.556 1.00 7.90  ?  41   HIS B CD2  1 
ATOM   6204  C CE1  . HIS B 1 75  ? -7.604  39.085  45.566 1.00 7.31  ?  41   HIS B CE1  1 
ATOM   6205  N NE2  . HIS B 1 75  ? -8.022  38.366  44.542 1.00 7.51  ?  41   HIS B NE2  1 
ATOM   6206  H H    . HIS B 1 75  ? -13.846 40.160  45.771 1.00 8.10  ?  41   HIS B H    1 
ATOM   6207  H HA   . HIS B 1 75  ? -11.401 41.066  44.990 1.00 8.39  ?  41   HIS B HA   1 
ATOM   6208  H HB2  . HIS B 1 75  ? -11.081 39.784  46.988 1.00 7.93  ?  41   HIS B HB2  1 
ATOM   6209  H HB3  . HIS B 1 75  ? -11.650 38.537  46.184 1.00 7.93  ?  41   HIS B HB3  1 
ATOM   6210  H HD2  . HIS B 1 75  ? -9.937  37.876  43.955 1.00 9.48  ?  41   HIS B HD2  1 
ATOM   6211  H HE1  . HIS B 1 75  ? -6.715  39.247  45.787 1.00 8.77  ?  41   HIS B HE1  1 
ATOM   6212  H HE2  . HIS B 1 75  ? -7.517  37.983  43.960 1.00 9.01  ?  41   HIS B HE2  1 
ATOM   6213  N N    . VAL B 1 76  ? -12.273 40.243  42.778 1.00 7.48  ?  42   VAL B N    1 
ATOM   6214  C CA   . VAL B 1 76  ? -13.127 39.868  41.646 1.00 7.32  ?  42   VAL B CA   1 
ATOM   6215  C C    . VAL B 1 76  ? -12.491 40.125  40.290 1.00 7.20  ?  42   VAL B C    1 
ATOM   6216  O O    . VAL B 1 76  ? -11.723 41.073  40.096 1.00 6.95  ?  42   VAL B O    1 
ATOM   6217  C CB   . VAL B 1 76  ? -14.479 40.629  41.763 1.00 7.80  ?  42   VAL B CB   1 
ATOM   6218  C CG1  . VAL B 1 76  ? -14.294 42.155  41.599 1.00 9.41  ?  42   VAL B CG1  1 
ATOM   6219  C CG2  . VAL B 1 76  ? -15.520 40.094  40.749 1.00 9.92  ?  42   VAL B CG2  1 
ATOM   6220  H H    . VAL B 1 76  ? -11.684 40.849  42.618 1.00 8.98  ?  42   VAL B H    1 
ATOM   6221  H HA   . VAL B 1 76  ? -13.237 38.905  41.675 1.00 8.79  ?  42   VAL B HA   1 
ATOM   6222  H HB   . VAL B 1 76  ? -14.823 40.469  42.656 1.00 9.36  ?  42   VAL B HB   1 
ATOM   6223  H HG11 . VAL B 1 76  ? -15.131 42.599  41.805 1.00 11.30 ?  42   VAL B HG11 1 
ATOM   6224  H HG12 . VAL B 1 76  ? -13.601 42.456  42.208 1.00 11.30 ?  42   VAL B HG12 1 
ATOM   6225  H HG13 . VAL B 1 76  ? -14.035 42.345  40.684 1.00 11.30 ?  42   VAL B HG13 1 
ATOM   6226  H HG21 . VAL B 1 76  ? -16.378 40.509  40.929 1.00 11.90 ?  42   VAL B HG21 1 
ATOM   6227  H HG22 . VAL B 1 76  ? -15.228 40.314  39.851 1.00 11.90 ?  42   VAL B HG22 1 
ATOM   6228  H HG23 . VAL B 1 76  ? -15.591 39.132  40.847 1.00 11.90 ?  42   VAL B HG23 1 
ATOM   6229  N N    . ARG B 1 77  ? -12.877 39.276  39.330 1.00 7.59  ?  43   ARG B N    1 
ATOM   6230  C CA   . ARG B 1 77  ? -12.665 39.524  37.913 1.00 7.97  ?  43   ARG B CA   1 
ATOM   6231  C C    . ARG B 1 77  ? -13.897 39.055  37.141 1.00 7.44  ?  43   ARG B C    1 
ATOM   6232  O O    . ARG B 1 77  ? -14.750 38.320  37.656 1.00 7.46  ?  43   ARG B O    1 
ATOM   6233  C CB   . ARG B 1 77  ? -11.406 38.827  37.385 1.00 7.91  ?  43   ARG B CB   1 
ATOM   6234  C CG   . ARG B 1 77  ? -11.440 37.314  37.488 1.00 7.74  ?  43   ARG B CG   1 
ATOM   6235  C CD   . ARG B 1 77  ? -10.174 36.662  36.946 1.00 8.25  ?  43   ARG B CD   1 
ATOM   6236  N NE   . ARG B 1 77  ? -10.188 35.207  37.072 1.00 8.55  ?  43   ARG B NE   1 
ATOM   6237  C CZ   . ARG B 1 77  ? -10.618 34.369  36.146 1.00 8.54  ?  43   ARG B CZ   1 
ATOM   6238  N NH1  . ARG B 1 77  ? -11.084 34.792  34.993 1.00 9.13  ?  43   ARG B NH1  1 
ATOM   6239  N NH2  . ARG B 1 77  ? -10.562 33.060  36.390 1.00 10.39 ?  43   ARG B NH2  1 
ATOM   6240  H H    . ARG B 1 77  ? -13.276 38.530  39.487 1.00 9.11  ?  43   ARG B H    1 
ATOM   6241  H HA   . ARG B 1 77  ? -12.555 40.478  37.776 1.00 9.57  ?  43   ARG B HA   1 
ATOM   6242  H HB2  . ARG B 1 77  ? -11.295 39.056  36.449 1.00 9.49  ?  43   ARG B HB2  1 
ATOM   6243  H HB3  . ARG B 1 77  ? -10.642 39.139  37.896 1.00 9.49  ?  43   ARG B HB3  1 
ATOM   6244  H HG2  . ARG B 1 77  ? -11.533 37.062  38.420 1.00 9.29  ?  43   ARG B HG2  1 
ATOM   6245  H HG3  . ARG B 1 77  ? -12.193 36.979  36.976 1.00 9.29  ?  43   ARG B HG3  1 
ATOM   6246  H HD2  . ARG B 1 77  ? -10.083 36.881  36.005 1.00 9.90  ?  43   ARG B HD2  1 
ATOM   6247  H HD3  . ARG B 1 77  ? -9.409  36.998  37.440 1.00 9.90  ?  43   ARG B HD3  1 
ATOM   6248  H HE   . ARG B 1 77  ? -9.893  34.869  37.806 1.00 10.26 ?  43   ARG B HE   1 
ATOM   6249  H HH11 . ARG B 1 77  ? -11.115 35.635  34.825 1.00 10.96 ?  43   ARG B HH11 1 
ATOM   6250  H HH12 . ARG B 1 77  ? -11.358 34.226  34.407 1.00 10.96 ?  43   ARG B HH12 1 
ATOM   6251  H HH21 . ARG B 1 77  ? -10.251 32.774  37.139 1.00 12.46 ?  43   ARG B HH21 1 
ATOM   6252  H HH22 . ARG B 1 77  ? -10.838 32.500  35.798 1.00 12.46 ?  43   ARG B HH22 1 
ATOM   6253  N N    . LYS B 1 78  ? -13.963 39.499  35.888 1.00 8.06  ?  44   LYS B N    1 
ATOM   6254  C CA   . LYS B 1 78  ? -15.005 39.143  34.928 1.00 7.75  ?  44   LYS B CA   1 
ATOM   6255  C C    . LYS B 1 78  ? -14.375 39.360  33.562 1.00 7.72  ?  44   LYS B C    1 
ATOM   6256  O O    . LYS B 1 78  ? -13.588 40.281  33.385 1.00 7.49  ?  44   LYS B O    1 
ATOM   6257  C CB   . LYS B 1 78  ? -16.226 40.063  35.099 1.00 7.81  ?  44   LYS B CB   1 
ATOM   6258  C CG   . LYS B 1 78  ? -17.475 39.594  34.364 1.00 9.39  ?  44   LYS B CG   1 
ATOM   6259  C CD   . LYS B 1 78  ? -18.633 40.593  34.471 1.00 8.73  ?  44   LYS B CD   1 
ATOM   6260  C CE   . LYS B 1 78  ? -19.762 40.185  33.558 1.00 8.34  ?  44   LYS B CE   1 
ATOM   6261  N NZ   . LYS B 1 78  ? -20.822 41.234  33.507 1.00 9.72  ?  44   LYS B NZ   1 
ATOM   6262  H H    . LYS B 1 78  ? -13.384 40.037  35.550 1.00 9.67  ?  44   LYS B H    1 
ATOM   6263  H HA   . LYS B 1 78  ? -15.303 38.225  35.028 1.00 9.30  ?  44   LYS B HA   1 
ATOM   6264  H HB2  . LYS B 1 78  ? -16.444 40.116  36.043 1.00 9.37  ?  44   LYS B HB2  1 
ATOM   6265  H HB3  . LYS B 1 78  ? -16.000 40.943  34.761 1.00 9.37  ?  44   LYS B HB3  1 
ATOM   6266  H HG2  . LYS B 1 78  ? -17.264 39.478  33.424 1.00 11.27 ?  44   LYS B HG2  1 
ATOM   6267  H HG3  . LYS B 1 78  ? -17.769 38.751  34.745 1.00 11.27 ?  44   LYS B HG3  1 
ATOM   6268  H HD2  . LYS B 1 78  ? -18.964 40.611  35.383 1.00 10.47 ?  44   LYS B HD2  1 
ATOM   6269  H HD3  . LYS B 1 78  ? -18.328 41.476  34.211 1.00 10.47 ?  44   LYS B HD3  1 
ATOM   6270  H HE2  . LYS B 1 78  ? -19.418 40.053  32.660 1.00 10.01 ?  44   LYS B HE2  1 
ATOM   6271  H HE3  . LYS B 1 78  ? -20.160 39.363  33.884 1.00 10.01 ?  44   LYS B HE3  1 
ATOM   6272  H HZ1  . LYS B 1 78  ? -21.048 41.480  34.332 1.00 11.66 ?  44   LYS B HZ1  1 
ATOM   6273  H HZ2  . LYS B 1 78  ? -20.524 41.947  33.065 1.00 11.66 ?  44   LYS B HZ2  1 
ATOM   6274  H HZ3  . LYS B 1 78  ? -21.544 40.918  33.092 1.00 11.66 ?  44   LYS B HZ3  1 
ATOM   6275  N N    . ASN B 1 79  ? -14.693 38.505  32.591 1.00 7.98  ?  45   ASN B N    1 
ATOM   6276  C CA   . ASN B 1 79  ? -14.033 38.648  31.296 1.00 8.36  ?  45   ASN B CA   1 
ATOM   6277  C C    . ASN B 1 79  ? -14.546 39.819  30.468 1.00 8.62  ?  45   ASN B C    1 
ATOM   6278  O O    . ASN B 1 79  ? -13.857 40.263  29.543 1.00 8.90  ?  45   ASN B O    1 
ATOM   6279  C CB   . ASN B 1 79  ? -14.144 37.351  30.494 1.00 8.66  ?  45   ASN B CB   1 
ATOM   6280  C CG   . ASN B 1 79  ? -13.340 36.233  31.095 1.00 8.16  ?  45   ASN B CG   1 
ATOM   6281  O OD1  . ASN B 1 79  ? -12.125 36.309  31.189 1.00 10.46 ?  45   ASN B OD1  1 
ATOM   6282  N ND2  . ASN B 1 79  ? -14.031 35.186  31.509 1.00 9.78  ?  45   ASN B ND2  1 
ATOM   6283  H H    . ASN B 1 79  ? -15.262 37.863  32.655 1.00 9.57  ?  45   ASN B H    1 
ATOM   6284  H HA   . ASN B 1 79  ? -13.091 38.814  31.460 1.00 10.04 ?  45   ASN B HA   1 
ATOM   6285  H HB2  . ASN B 1 79  ? -15.073 37.073  30.468 1.00 10.39 ?  45   ASN B HB2  1 
ATOM   6286  H HB3  . ASN B 1 79  ? -13.819 37.505  29.594 1.00 10.39 ?  45   ASN B HB3  1 
ATOM   6287  H HD21 . ASN B 1 79  ? -13.625 34.515  31.862 1.00 11.74 ?  45   ASN B HD21 1 
ATOM   6288  H HD22 . ASN B 1 79  ? -14.887 35.175  31.426 1.00 11.74 ?  45   ASN B HD22 1 
ATOM   6289  N N    . THR B 1 80  ? -15.734 40.307  30.782 1.00 8.26  ?  46   THR B N    1 
ATOM   6290  C CA   . THR B 1 80  ? -16.341 41.444  30.102 1.00 9.04  ?  46   THR B CA   1 
ATOM   6291  C C    . THR B 1 80  ? -16.758 42.445  31.168 1.00 10.21 ?  46   THR B C    1 
ATOM   6292  O O    . THR B 1 80  ? -16.673 42.175  32.367 1.00 10.12 ?  46   THR B O    1 
ATOM   6293  C CB   . THR B 1 80  ? -17.551 41.001  29.269 1.00 10.52 ?  46   THR B CB   1 
ATOM   6294  O OG1  . THR B 1 80  ? -18.477 40.335  30.123 1.00 11.20 ?  46   THR B OG1  1 
ATOM   6295  C CG2  . THR B 1 80  ? -17.136 40.077  28.116 1.00 9.97  ?  46   THR B CG2  1 
ATOM   6296  H H    . THR B 1 80  ? -16.228 39.986  31.408 1.00 9.91  ?  46   THR B H    1 
ATOM   6297  H HA   . THR B 1 80  ? -15.708 41.866  29.501 1.00 10.85 ?  46   THR B HA   1 
ATOM   6298  H HB   . THR B 1 80  ? -17.972 41.778  28.868 1.00 12.63 ?  46   THR B HB   1 
ATOM   6299  H HG1  . THR B 1 80  ? -19.121 40.038  29.673 1.00 13.44 ?  46   THR B HG1  1 
ATOM   6300  H HG21 . THR B 1 80  ? -17.924 39.721  27.676 1.00 11.96 ?  46   THR B HG21 1 
ATOM   6301  H HG22 . THR B 1 80  ? -16.610 40.570  27.468 1.00 11.96 ?  46   THR B HG22 1 
ATOM   6302  H HG23 . THR B 1 80  ? -16.606 39.339  28.456 1.00 11.96 ?  46   THR B HG23 1 
ATOM   6303  N N    . ALA B 1 81  ? -17.214 43.611  30.716 1.00 9.37  ?  47   ALA B N    1 
ATOM   6304  C CA   . ALA B 1 81  ? -17.582 44.683  31.622 1.00 8.93  ?  47   ALA B CA   1 
ATOM   6305  C C    . ALA B 1 81  ? -18.669 44.247  32.600 1.00 9.41  ?  47   ALA B C    1 
ATOM   6306  O O    . ALA B 1 81  ? -19.578 43.485  32.273 1.00 8.70  ?  47   ALA B O    1 
ATOM   6307  C CB   . ALA B 1 81  ? -18.101 45.883  30.813 1.00 10.13 ?  47   ALA B CB   1 
ATOM   6308  H H    . ALA B 1 81  ? -17.319 43.803  29.885 1.00 11.24 ?  47   ALA B H    1 
ATOM   6309  H HA   . ALA B 1 81  ? -16.800 44.940  32.135 1.00 10.71 ?  47   ALA B HA   1 
ATOM   6310  H HB1  . ALA B 1 81  ? -18.343 46.595  31.425 1.00 12.15 ?  47   ALA B HB1  1 
ATOM   6311  H HB2  . ALA B 1 81  ? -17.402 46.185  30.213 1.00 12.15 ?  47   ALA B HB2  1 
ATOM   6312  H HB3  . ALA B 1 81  ? -18.879 45.607  30.303 1.00 12.15 ?  47   ALA B HB3  1 
ATOM   6313  N N    . TYR B 1 82  ? -18.597 44.790  33.810 1.00 8.80  ?  48   TYR B N    1 
ATOM   6314  C CA   . TYR B 1 82  ? -19.681 44.623  34.770 1.00 8.69  ?  48   TYR B CA   1 
ATOM   6315  C C    . TYR B 1 82  ? -20.930 45.362  34.293 1.00 10.67 ?  48   TYR B C    1 
ATOM   6316  O O    . TYR B 1 82  ? -20.848 46.409  33.647 1.00 11.37 ?  48   TYR B O    1 
ATOM   6317  C CB   . TYR B 1 82  ? -19.235 45.158  36.140 1.00 10.11 ?  48   TYR B CB   1 
ATOM   6318  C CG   . TYR B 1 82  ? -18.035 44.390  36.661 1.00 8.15  ?  48   TYR B CG   1 
ATOM   6319  C CD1  . TYR B 1 82  ? -18.207 43.185  37.294 1.00 8.86  ?  48   TYR B CD1  1 
ATOM   6320  C CD2  . TYR B 1 82  ? -16.745 44.861  36.486 1.00 9.08  ?  48   TYR B CD2  1 
ATOM   6321  C CE1  . TYR B 1 82  ? -17.127 42.446  37.720 1.00 7.97  ?  48   TYR B CE1  1 
ATOM   6322  C CE2  . TYR B 1 82  ? -15.651 44.141  36.933 1.00 7.81  ?  48   TYR B CE2  1 
ATOM   6323  C CZ   . TYR B 1 82  ? -15.866 42.908  37.532 1.00 7.88  ?  48   TYR B CZ   1 
ATOM   6324  O OH   . TYR B 1 82  ? -14.784 42.161  37.987 1.00 8.00  ?  48   TYR B OH   1 
ATOM   6325  H H    . TYR B 1 82  ? -17.935 45.257  34.099 1.00 10.56 ?  48   TYR B H    1 
ATOM   6326  H HA   . TYR B 1 82  ? -19.908 43.684  34.864 1.00 10.43 ?  48   TYR B HA   1 
ATOM   6327  H HB2  . TYR B 1 82  ? -18.989 46.092  36.057 1.00 12.13 ?  48   TYR B HB2  1 
ATOM   6328  H HB3  . TYR B 1 82  ? -19.962 45.061  36.775 1.00 12.13 ?  48   TYR B HB3  1 
ATOM   6329  H HD1  . TYR B 1 82  ? -19.068 42.862  37.438 1.00 10.63 ?  48   TYR B HD1  1 
ATOM   6330  H HD2  . TYR B 1 82  ? -16.611 45.677  36.061 1.00 10.89 ?  48   TYR B HD2  1 
ATOM   6331  H HE1  . TYR B 1 82  ? -17.263 41.626  38.138 1.00 9.57  ?  48   TYR B HE1  1 
ATOM   6332  H HE2  . TYR B 1 82  ? -14.790 44.476  36.834 1.00 9.37  ?  48   TYR B HE2  1 
ATOM   6333  H HH   . TYR B 1 82  ? -14.064 42.540  37.776 1.00 9.60  ?  48   TYR B HH   1 
ATOM   6334  N N    . THR B 1 83  ? -22.094 44.806  34.616 1.00 9.59  ?  49   THR B N    1 
ATOM   6335  C CA   . THR B 1 83  ? -23.344 45.523  34.381 1.00 10.24 ?  49   THR B CA   1 
ATOM   6336  C C    . THR B 1 83  ? -23.476 46.649  35.403 1.00 10.68 ?  49   THR B C    1 
ATOM   6337  O O    . THR B 1 83  ? -22.733 46.724  36.385 1.00 9.71  ?  49   THR B O    1 
ATOM   6338  C CB   . THR B 1 83  ? -24.526 44.572  34.553 1.00 10.09 ?  49   THR B CB   1 
ATOM   6339  O OG1  . THR B 1 83  ? -24.603 44.235  35.943 1.00 10.88 ?  49   THR B OG1  1 
ATOM   6340  C CG2  . THR B 1 83  ? -24.390 43.327  33.706 1.00 12.21 ?  49   THR B CG2  1 
ATOM   6341  H H    . THR B 1 83  ? -22.187 44.026  34.966 1.00 11.51 ?  49   THR B H    1 
ATOM   6342  H HA   . THR B 1 83  ? -23.351 45.887  33.482 1.00 12.29 ?  49   THR B HA   1 
ATOM   6343  H HB   . THR B 1 83  ? -25.346 44.997  34.256 1.00 12.11 ?  49   THR B HB   1 
ATOM   6344  H HG1  . THR B 1 83  ? -25.002 43.502  36.039 1.00 13.05 ?  49   THR B HG1  1 
ATOM   6345  H HG21 . THR B 1 83  ? -25.181 42.774  33.799 1.00 14.65 ?  49   THR B HG21 1 
ATOM   6346  H HG22 . THR B 1 83  ? -24.285 43.570  32.772 1.00 14.65 ?  49   THR B HG22 1 
ATOM   6347  H HG23 . THR B 1 83  ? -23.614 42.817  33.987 1.00 14.65 ?  49   THR B HG23 1 
ATOM   6348  N N    A ASP B 1 84  ? -24.446 47.540  35.170 0.50 11.94 ?  50   ASP B N    1 
ATOM   6349  N N    B ASP B 1 84  ? -24.449 47.538  35.185 0.50 11.92 ?  50   ASP B N    1 
ATOM   6350  C CA   A ASP B 1 84  ? -24.705 48.601  36.137 0.50 11.09 ?  50   ASP B CA   1 
ATOM   6351  C CA   B ASP B 1 84  ? -24.670 48.606  36.155 0.50 11.09 ?  50   ASP B CA   1 
ATOM   6352  C C    A ASP B 1 84  ? -25.003 48.024  37.515 0.50 10.09 ?  50   ASP B C    1 
ATOM   6353  C C    B ASP B 1 84  ? -25.013 48.036  37.528 0.50 10.10 ?  50   ASP B C    1 
ATOM   6354  O O    A ASP B 1 84  ? -24.498 48.521  38.529 0.50 11.22 ?  50   ASP B O    1 
ATOM   6355  O O    B ASP B 1 84  ? -24.539 48.540  38.552 0.50 11.20 ?  50   ASP B O    1 
ATOM   6356  C CB   A ASP B 1 84  ? -25.877 49.476  35.685 0.50 13.08 ?  50   ASP B CB   1 
ATOM   6357  C CB   B ASP B 1 84  ? -25.762 49.569  35.678 0.50 13.10 ?  50   ASP B CB   1 
ATOM   6358  C CG   A ASP B 1 84  ? -25.624 50.168  34.365 0.50 16.41 ?  50   ASP B CG   1 
ATOM   6359  C CG   B ASP B 1 84  ? -25.913 50.783  36.593 0.50 13.33 ?  50   ASP B CG   1 
ATOM   6360  O OD1  A ASP B 1 84  ? -24.451 50.358  33.994 0.50 16.02 ?  50   ASP B OD1  1 
ATOM   6361  O OD1  B ASP B 1 84  ? -25.015 51.658  36.614 0.50 18.79 ?  50   ASP B OD1  1 
ATOM   6362  O OD2  A ASP B 1 84  ? -26.618 50.544  33.706 0.50 22.54 ?  50   ASP B OD2  1 
ATOM   6363  O OD2  B ASP B 1 84  ? -26.936 50.843  37.306 0.50 19.93 ?  50   ASP B OD2  1 
ATOM   6364  H H    A ASP B 1 84  ? -24.954 47.549  34.476 0.50 14.33 ?  50   ASP B H    1 
ATOM   6365  H H    B ASP B 1 84  ? -24.977 47.542  34.506 0.50 14.31 ?  50   ASP B H    1 
ATOM   6366  H HA   A ASP B 1 84  ? -23.913 49.158  36.189 0.50 13.31 ?  50   ASP B HA   1 
ATOM   6367  H HA   B ASP B 1 84  ? -23.851 49.121  36.232 0.50 13.31 ?  50   ASP B HA   1 
ATOM   6368  H HB2  A ASP B 1 84  ? -26.665 48.919  35.585 0.50 15.69 ?  50   ASP B HB2  1 
ATOM   6369  H HB2  B ASP B 1 84  ? -25.537 49.888  34.790 0.50 15.72 ?  50   ASP B HB2  1 
ATOM   6370  H HB3  A ASP B 1 84  ? -26.036 50.159  36.355 0.50 15.69 ?  50   ASP B HB3  1 
ATOM   6371  H HB3  B ASP B 1 84  ? -26.611 49.100  35.657 0.50 15.72 ?  50   ASP B HB3  1 
ATOM   6372  N N    . GLU B 1 85  ? -25.843 46.989  37.572 1.00 10.60 ?  51   GLU B N    1 
ATOM   6373  C CA   . GLU B 1 85  ? -26.161 46.359  38.848 1.00 11.67 ?  51   GLU B CA   1 
ATOM   6374  C C    . GLU B 1 85  ? -24.899 45.826  39.524 1.00 10.69 ?  51   GLU B C    1 
ATOM   6375  O O    . GLU B 1 85  ? -24.737 45.953  40.741 1.00 11.28 ?  51   GLU B O    1 
ATOM   6376  C CB   . GLU B 1 85  ? -27.170 45.228  38.637 1.00 13.80 ?  51   GLU B CB   1 
ATOM   6377  C CG   . GLU B 1 85  ? -27.451 44.385  39.892 1.00 15.88 ?  51   GLU B CG   1 
ATOM   6378  C CD   . GLU B 1 85  ? -28.309 43.136  39.636 1.00 19.41 ?  51   GLU B CD   1 
ATOM   6379  O OE1  . GLU B 1 85  ? -28.300 42.587  38.515 1.00 18.84 ?  51   GLU B OE1  1 
ATOM   6380  O OE2  . GLU B 1 85  ? -28.964 42.665  40.594 1.00 24.61 ?  51   GLU B OE2  1 
ATOM   6381  H H    . GLU B 1 85  ? -26.235 46.641  36.891 1.00 12.72 ?  51   GLU B H    1 
ATOM   6382  H HA   . GLU B 1 85  ? -26.565 47.019  39.432 1.00 14.00 ?  51   GLU B HA   1 
ATOM   6383  H HB2  . GLU B 1 85  ? -28.012 45.615  38.349 1.00 16.56 ?  51   GLU B HB2  1 
ATOM   6384  H HB3  . GLU B 1 85  ? -26.828 44.631  37.953 1.00 16.56 ?  51   GLU B HB3  1 
ATOM   6385  H HG2  . GLU B 1 85  ? -26.605 44.089  40.263 1.00 19.06 ?  51   GLU B HG2  1 
ATOM   6386  H HG3  . GLU B 1 85  ? -27.921 44.937  40.538 1.00 19.06 ?  51   GLU B HG3  1 
ATOM   6387  N N    . GLU B 1 86  ? -23.992 45.228  38.742 1.00 10.29 ?  52   GLU B N    1 
ATOM   6388  C CA   . GLU B 1 86  ? -22.750 44.710  39.296 1.00 9.72  ?  52   GLU B CA   1 
ATOM   6389  C C    . GLU B 1 86  ? -21.836 45.820  39.791 1.00 10.36 ?  52   GLU B C    1 
ATOM   6390  O O    . GLU B 1 86  ? -21.205 45.673  40.847 1.00 10.04 ?  52   GLU B O    1 
ATOM   6391  C CB   . GLU B 1 86  ? -22.073 43.827  38.258 1.00 9.63  ?  52   GLU B CB   1 
ATOM   6392  C CG   . GLU B 1 86  ? -22.851 42.530  38.006 1.00 10.66 ?  52   GLU B CG   1 
ATOM   6393  C CD   . GLU B 1 86  ? -22.338 41.696  36.856 1.00 10.61 ?  52   GLU B CD   1 
ATOM   6394  O OE1  . GLU B 1 86  ? -21.680 42.237  35.962 1.00 9.92  ?  52   GLU B OE1  1 
ATOM   6395  O OE2  . GLU B 1 86  ? -22.633 40.481  36.858 1.00 12.58 ?  52   GLU B OE2  1 
ATOM   6396  H H    . GLU B 1 86  ? -24.076 45.113  37.893 1.00 12.34 ?  52   GLU B H    1 
ATOM   6397  H HA   . GLU B 1 86  ? -22.947 44.161  40.071 1.00 11.67 ?  52   GLU B HA   1 
ATOM   6398  H HB2  . GLU B 1 86  ? -22.012 44.311  37.420 1.00 11.56 ?  52   GLU B HB2  1 
ATOM   6399  H HB3  . GLU B 1 86  ? -21.185 43.592  38.571 1.00 11.56 ?  52   GLU B HB3  1 
ATOM   6400  H HG2  . GLU B 1 86  ? -22.804 41.983  38.806 1.00 12.79 ?  52   GLU B HG2  1 
ATOM   6401  H HG3  . GLU B 1 86  ? -23.774 42.757  37.813 1.00 12.79 ?  52   GLU B HG3  1 
ATOM   6402  N N    . ILE B 1 87  ? -21.759 46.946  39.064 1.00 9.91  ?  53   ILE B N    1 
ATOM   6403  C CA   . ILE B 1 87  ? -20.980 48.079  39.551 1.00 9.52  ?  53   ILE B CA   1 
ATOM   6404  C C    . ILE B 1 87  ? -21.541 48.576  40.873 1.00 10.61 ?  53   ILE B C    1 
ATOM   6405  O O    . ILE B 1 87  ? -20.790 48.889  41.796 1.00 10.52 ?  53   ILE B O    1 
ATOM   6406  C CB   . ILE B 1 87  ? -20.932 49.209  38.504 1.00 9.37  ?  53   ILE B CB   1 
ATOM   6407  C CG1  . ILE B 1 87  ? -20.093 48.816  37.286 1.00 10.37 ?  53   ILE B CG1  1 
ATOM   6408  C CG2  . ILE B 1 87  ? -20.418 50.499  39.136 1.00 12.56 ?  53   ILE B CG2  1 
ATOM   6409  C CD1  . ILE B 1 87  ? -18.621 48.565  37.558 1.00 10.52 ?  53   ILE B CD1  1 
ATOM   6410  H H    . ILE B 1 87  ? -22.141 47.070  38.304 1.00 11.89 ?  53   ILE B H    1 
ATOM   6411  H HA   . ILE B 1 87  ? -20.070 47.776  39.698 1.00 11.42 ?  53   ILE B HA   1 
ATOM   6412  H HB   . ILE B 1 87  ? -21.837 49.359  38.190 1.00 11.25 ?  53   ILE B HB   1 
ATOM   6413  H HG12 . ILE B 1 87  ? -20.461 47.999  36.913 1.00 12.44 ?  53   ILE B HG12 1 
ATOM   6414  H HG13 . ILE B 1 87  ? -20.148 49.532  36.634 1.00 12.44 ?  53   ILE B HG13 1 
ATOM   6415  H HG21 . ILE B 1 87  ? -20.183 51.124  38.432 1.00 15.08 ?  53   ILE B HG21 1 
ATOM   6416  H HG22 . ILE B 1 87  ? -21.115 50.876  39.694 1.00 15.08 ?  53   ILE B HG22 1 
ATOM   6417  H HG23 . ILE B 1 87  ? -19.636 50.297  39.674 1.00 15.08 ?  53   ILE B HG23 1 
ATOM   6418  H HD11 . ILE B 1 87  ? -18.163 48.426  36.714 1.00 12.63 ?  53   ILE B HD11 1 
ATOM   6419  H HD12 . ILE B 1 87  ? -18.248 49.336  38.013 1.00 12.63 ?  53   ILE B HD12 1 
ATOM   6420  H HD13 . ILE B 1 87  ? -18.533 47.776  38.116 1.00 12.63 ?  53   ILE B HD13 1 
ATOM   6421  N N    . ASN B 1 88  ? -22.866 48.661  40.987 1.00 10.80 ?  54   ASN B N    1 
ATOM   6422  C CA   . ASN B 1 88  ? -23.456 49.093  42.249 1.00 11.03 ?  54   ASN B CA   1 
ATOM   6423  C C    . ASN B 1 88  ? -23.104 48.136  43.377 1.00 10.74 ?  54   ASN B C    1 
ATOM   6424  O O    . ASN B 1 88  ? -22.833 48.561  44.509 1.00 11.17 ?  54   ASN B O    1 
ATOM   6425  C CB   . ASN B 1 88  ? -24.977 49.180  42.118 1.00 13.39 ?  54   ASN B CB   1 
ATOM   6426  C CG   . ASN B 1 88  ? -25.431 50.301  41.212 1.00 18.04 ?  54   ASN B CG   1 
ATOM   6427  O OD1  . ASN B 1 88  ? -24.693 51.238  40.932 1.00 19.45 ?  54   ASN B OD1  1 
ATOM   6428  N ND2  . ASN B 1 88  ? -26.654 50.185  40.726 1.00 23.58 ?  54   ASN B ND2  1 
ATOM   6429  H H    . ASN B 1 88  ? -23.431 48.479  40.365 1.00 12.96 ?  54   ASN B H    1 
ATOM   6430  H HA   . ASN B 1 88  ? -23.109 49.974  42.461 1.00 13.23 ?  54   ASN B HA   1 
ATOM   6431  H HB2  . ASN B 1 88  ? -25.310 48.346  41.751 1.00 16.07 ?  54   ASN B HB2  1 
ATOM   6432  H HB3  . ASN B 1 88  ? -25.360 49.332  42.996 1.00 16.07 ?  54   ASN B HB3  1 
ATOM   6433  H HD21 . ASN B 1 88  ? -26.968 50.792  40.204 1.00 28.30 ?  54   ASN B HD21 1 
ATOM   6434  H HD22 . ASN B 1 88  ? -27.135 49.503  40.931 1.00 28.30 ?  54   ASN B HD22 1 
ATOM   6435  N N    . TYR B 1 89  ? -23.117 46.834  43.089 1.00 9.76  ?  55   TYR B N    1 
ATOM   6436  C CA   . TYR B 1 89  ? -22.722 45.853  44.096 1.00 9.54  ?  55   TYR B CA   1 
ATOM   6437  C C    . TYR B 1 89  ? -21.267 46.066  44.502 1.00 9.13  ?  55   TYR B C    1 
ATOM   6438  O O    . TYR B 1 89  ? -20.956 46.153  45.694 1.00 10.11 ?  55   TYR B O    1 
ATOM   6439  C CB   . TYR B 1 89  ? -22.932 44.461  43.516 1.00 10.53 ?  55   TYR B CB   1 
ATOM   6440  C CG   . TYR B 1 89  ? -22.550 43.284  44.385 1.00 11.32 ?  55   TYR B CG   1 
ATOM   6441  C CD1  . TYR B 1 89  ? -23.248 42.990  45.548 1.00 11.45 ?  55   TYR B CD1  1 
ATOM   6442  C CD2  . TYR B 1 89  ? -21.530 42.417  43.999 1.00 10.84 ?  55   TYR B CD2  1 
ATOM   6443  C CE1  . TYR B 1 89  ? -22.907 41.876  46.326 1.00 12.37 ?  55   TYR B CE1  1 
ATOM   6444  C CE2  . TYR B 1 89  ? -21.208 41.315  44.748 1.00 11.01 ?  55   TYR B CE2  1 
ATOM   6445  C CZ   . TYR B 1 89  ? -21.887 41.052  45.903 1.00 12.59 ?  55   TYR B CZ   1 
ATOM   6446  O OH   . TYR B 1 89  ? -21.530 39.941  46.632 1.00 13.55 ?  55   TYR B OH   1 
ATOM   6447  H H    . TYR B 1 89  ? -23.346 46.498  42.331 1.00 11.71 ?  55   TYR B H    1 
ATOM   6448  H HA   . TYR B 1 89  ? -23.267 45.944  44.893 1.00 11.45 ?  55   TYR B HA   1 
ATOM   6449  H HB2  . TYR B 1 89  ? -23.875 44.363  43.310 1.00 12.64 ?  55   TYR B HB2  1 
ATOM   6450  H HB3  . TYR B 1 89  ? -22.406 44.393  42.704 1.00 12.64 ?  55   TYR B HB3  1 
ATOM   6451  H HD1  . TYR B 1 89  ? -23.951 43.539  45.814 1.00 13.74 ?  55   TYR B HD1  1 
ATOM   6452  H HD2  . TYR B 1 89  ? -21.059 42.590  43.216 1.00 13.00 ?  55   TYR B HD2  1 
ATOM   6453  H HE1  . TYR B 1 89  ? -23.363 41.694  47.116 1.00 14.85 ?  55   TYR B HE1  1 
ATOM   6454  H HE2  . TYR B 1 89  ? -20.526 40.746  44.469 1.00 13.21 ?  55   TYR B HE2  1 
ATOM   6455  H HH   . TYR B 1 89  ? -22.154 39.725  47.152 1.00 16.26 ?  55   TYR B HH   1 
ATOM   6456  N N    . LEU B 1 90  ? -20.360 46.185  43.528 1.00 9.02  ?  56   LEU B N    1 
ATOM   6457  C CA   . LEU B 1 90  ? -18.963 46.426  43.879 1.00 8.90  ?  56   LEU B CA   1 
ATOM   6458  C C    . LEU B 1 90  ? -18.805 47.679  44.733 1.00 9.58  ?  56   LEU B C    1 
ATOM   6459  O O    . LEU B 1 90  ? -18.058 47.682  45.720 1.00 9.81  ?  56   LEU B O    1 
ATOM   6460  C CB   . LEU B 1 90  ? -18.096 46.521  42.623 1.00 9.35  ?  56   LEU B CB   1 
ATOM   6461  C CG   . LEU B 1 90  ? -18.014 45.240  41.796 1.00 8.10  ?  56   LEU B CG   1 
ATOM   6462  C CD1  . LEU B 1 90  ? -17.154 45.407  40.557 1.00 10.31 ?  56   LEU B CD1  1 
ATOM   6463  C CD2  . LEU B 1 90  ? -17.493 44.078  42.654 1.00 11.30 ?  56   LEU B CD2  1 
ATOM   6464  H H    . LEU B 1 90  ? -20.524 46.132  42.685 1.00 10.83 ?  56   LEU B H    1 
ATOM   6465  H HA   . LEU B 1 90  ? -18.649 45.669  44.397 1.00 10.68 ?  56   LEU B HA   1 
ATOM   6466  H HB2  . LEU B 1 90  ? -18.460 47.214  42.051 1.00 11.23 ?  56   LEU B HB2  1 
ATOM   6467  H HB3  . LEU B 1 90  ? -17.193 46.752  42.891 1.00 11.23 ?  56   LEU B HB3  1 
ATOM   6468  H HG   . LEU B 1 90  ? -18.911 45.029  41.491 1.00 9.72  ?  56   LEU B HG   1 
ATOM   6469  H HD11 . LEU B 1 90  ? -17.206 44.598  40.025 1.00 12.37 ?  56   LEU B HD11 1 
ATOM   6470  H HD12 . LEU B 1 90  ? -17.482 46.163  40.044 1.00 12.37 ?  56   LEU B HD12 1 
ATOM   6471  H HD13 . LEU B 1 90  ? -16.236 45.566  40.829 1.00 12.37 ?  56   LEU B HD13 1 
ATOM   6472  H HD21 . LEU B 1 90  ? -17.375 43.297  42.090 1.00 13.56 ?  56   LEU B HD21 1 
ATOM   6473  H HD22 . LEU B 1 90  ? -16.643 44.332  43.047 1.00 13.56 ?  56   LEU B HD22 1 
ATOM   6474  H HD23 . LEU B 1 90  ? -18.137 43.887  43.353 1.00 13.56 ?  56   LEU B HD23 1 
ATOM   6475  N N    . ALA B 1 91  ? -19.506 48.763  44.379 1.00 9.81  ?  57   ALA B N    1 
ATOM   6476  C CA   . ALA B 1 91  ? -19.361 50.036  45.073 1.00 9.65  ?  57   ALA B CA   1 
ATOM   6477  C C    . ALA B 1 91  ? -19.884 49.986  46.499 1.00 10.15 ?  57   ALA B C    1 
ATOM   6478  O O    . ALA B 1 91  ? -19.568 50.892  47.288 1.00 12.46 ?  57   ALA B O    1 
ATOM   6479  C CB   . ALA B 1 91  ? -20.075 51.114  44.256 1.00 11.08 ?  57   ALA B CB   1 
ATOM   6480  H H    . ALA B 1 91  ? -20.075 48.782  43.734 1.00 11.77 ?  57   ALA B H    1 
ATOM   6481  H HA   . ALA B 1 91  ? -18.425 50.282  45.137 1.00 11.58 ?  57   ALA B HA   1 
ATOM   6482  H HB1  . ALA B 1 91  ? -19.921 51.978  44.669 1.00 13.29 ?  57   ALA B HB1  1 
ATOM   6483  H HB2  . ALA B 1 91  ? -19.720 51.112  43.353 1.00 13.29 ?  57   ALA B HB2  1 
ATOM   6484  H HB3  . ALA B 1 91  ? -21.025 50.920  44.238 1.00 13.29 ?  57   ALA B HB3  1 
ATOM   6485  N N    . SER B 1 92  ? -20.653 48.956  46.847 1.00 10.36 ?  58   SER B N    1 
ATOM   6486  C CA   . SER B 1 92  ? -21.158 48.813  48.207 1.00 9.73  ?  58   SER B CA   1 
ATOM   6487  C C    . SER B 1 92  ? -20.141 48.220  49.168 1.00 10.79 ?  58   SER B C    1 
ATOM   6488  O O    . SER B 1 92  ? -20.394 48.210  50.379 1.00 12.50 ?  58   SER B O    1 
ATOM   6489  C CB   . SER B 1 92  ? -22.417 47.953  48.223 1.00 11.83 ?  58   SER B CB   1 
ATOM   6490  O OG   . SER B 1 92  ? -22.141 46.579  48.058 1.00 11.60 ?  58   SER B OG   1 
ATOM   6491  H H    . SER B 1 92  ? -20.895 48.327  46.313 1.00 12.43 ?  58   SER B H    1 
ATOM   6492  H HA   . SER B 1 92  ? -21.395 49.697  48.530 1.00 11.68 ?  58   SER B HA   1 
ATOM   6493  H HB2  . SER B 1 92  ? -22.865 48.077  49.075 1.00 14.19 ?  58   SER B HB2  1 
ATOM   6494  H HB3  . SER B 1 92  ? -22.996 48.240  47.499 1.00 14.19 ?  58   SER B HB3  1 
ATOM   6495  H HG   . SER B 1 92  ? -21.718 46.455  47.343 1.00 13.92 ?  58   SER B HG   1 
ATOM   6496  N N    . PHE B 1 93  ? -18.993 47.741  48.673 1.00 9.92  ?  59   PHE B N    1 
ATOM   6497  C CA   . PHE B 1 93  ? -17.966 47.182  49.541 1.00 10.00 ?  59   PHE B CA   1 
ATOM   6498  C C    . PHE B 1 93  ? -16.957 48.256  49.914 1.00 10.02 ?  59   PHE B C    1 
ATOM   6499  O O    . PHE B 1 93  ? -16.615 49.106  49.090 1.00 11.97 ?  59   PHE B O    1 
ATOM   6500  C CB   . PHE B 1 93  ? -17.223 46.047  48.830 1.00 9.56  ?  59   PHE B CB   1 
ATOM   6501  C CG   . PHE B 1 93  ? -18.050 44.822  48.649 1.00 9.77  ?  59   PHE B CG   1 
ATOM   6502  C CD1  . PHE B 1 93  ? -18.879 44.704  47.555 1.00 10.39 ?  59   PHE B CD1  1 
ATOM   6503  C CD2  . PHE B 1 93  ? -18.012 43.790  49.573 1.00 9.49  ?  59   PHE B CD2  1 
ATOM   6504  C CE1  . PHE B 1 93  ? -19.689 43.601  47.385 1.00 9.96  ?  59   PHE B CE1  1 
ATOM   6505  C CE2  . PHE B 1 93  ? -18.816 42.680  49.412 1.00 10.64 ?  59   PHE B CE2  1 
ATOM   6506  C CZ   . PHE B 1 93  ? -19.645 42.570  48.316 1.00 10.39 ?  59   PHE B CZ   1 
ATOM   6507  H H    . PHE B 1 93  ? -18.788 47.730  47.838 1.00 11.90 ?  59   PHE B H    1 
ATOM   6508  H HA   . PHE B 1 93  ? -18.376 46.835  50.349 1.00 12.00 ?  59   PHE B HA   1 
ATOM   6509  H HB2  . PHE B 1 93  ? -16.949 46.354  47.952 1.00 11.47 ?  59   PHE B HB2  1 
ATOM   6510  H HB3  . PHE B 1 93  ? -16.444 45.805  49.355 1.00 11.47 ?  59   PHE B HB3  1 
ATOM   6511  H HD1  . PHE B 1 93  ? -18.892 45.382  46.919 1.00 12.47 ?  59   PHE B HD1  1 
ATOM   6512  H HD2  . PHE B 1 93  ? -17.441 43.845  50.305 1.00 11.38 ?  59   PHE B HD2  1 
ATOM   6513  H HE1  . PHE B 1 93  ? -20.260 43.548  46.653 1.00 11.95 ?  59   PHE B HE1  1 
ATOM   6514  H HE2  . PHE B 1 93  ? -18.798 42.001  50.048 1.00 12.77 ?  59   PHE B HE2  1 
ATOM   6515  H HZ   . PHE B 1 93  ? -20.171 41.812  48.201 1.00 12.47 ?  59   PHE B HZ   1 
ATOM   6516  N N    . PRO B 1 94  ? -16.449 48.248  51.140 1.00 9.00  ?  60   PRO B N    1 
ATOM   6517  C CA   . PRO B 1 94  ? -15.448 49.267  51.505 1.00 10.11 ?  60   PRO B CA   1 
ATOM   6518  C C    . PRO B 1 94  ? -14.105 49.084  50.826 1.00 9.31  ?  60   PRO B C    1 
ATOM   6519  O O    . PRO B 1 94  ? -13.358 50.054  50.667 1.00 9.26  ?  60   PRO B O    1 
ATOM   6520  C CB   . PRO B 1 94  ? -15.335 49.129  53.025 1.00 10.18 ?  60   PRO B CB   1 
ATOM   6521  C CG   . PRO B 1 94  ? -15.892 47.757  53.326 1.00 12.83 ?  60   PRO B CG   1 
ATOM   6522  C CD   . PRO B 1 94  ? -16.926 47.477  52.296 1.00 9.99  ?  60   PRO B CD   1 
ATOM   6523  H HA   . PRO B 1 94  ? -15.792 50.147  51.287 1.00 12.14 ?  60   PRO B HA   1 
ATOM   6524  H HB2  . PRO B 1 94  ? -14.406 49.195  53.296 1.00 12.22 ?  60   PRO B HB2  1 
ATOM   6525  H HB3  . PRO B 1 94  ? -15.858 49.820  53.460 1.00 12.22 ?  60   PRO B HB3  1 
ATOM   6526  H HG2  . PRO B 1 94  ? -15.179 47.101  53.279 1.00 15.39 ?  60   PRO B HG2  1 
ATOM   6527  H HG3  . PRO B 1 94  ? -16.286 47.756  54.212 1.00 15.39 ?  60   PRO B HG3  1 
ATOM   6528  H HD2  . PRO B 1 94  ? -16.963 46.530  52.090 1.00 11.99 ?  60   PRO B HD2  1 
ATOM   6529  H HD3  . PRO B 1 94  ? -17.798 47.788  52.585 1.00 11.99 ?  60   PRO B HD3  1 
ATOM   6530  N N    . LEU B 1 95  ? -13.757 47.856  50.443 1.00 8.97  ?  61   LEU B N    1 
ATOM   6531  C CA   . LEU B 1 95  ? -12.436 47.541  49.902 1.00 8.99  ?  61   LEU B CA   1 
ATOM   6532  C C    . LEU B 1 95  ? -12.622 46.468  48.844 1.00 9.59  ?  61   LEU B C    1 
ATOM   6533  O O    . LEU B 1 95  ? -13.224 45.420  49.123 1.00 8.42  ?  61   LEU B O    1 
ATOM   6534  C CB   . LEU B 1 95  ? -11.497 47.064  51.016 1.00 9.11  ?  61   LEU B CB   1 
ATOM   6535  C CG   . LEU B 1 95  ? -10.061 46.762  50.634 1.00 8.76  ?  61   LEU B CG   1 
ATOM   6536  C CD1  . LEU B 1 95  ? -9.380  47.978  50.000 1.00 10.66 ?  61   LEU B CD1  1 
ATOM   6537  C CD2  . LEU B 1 95  ? -9.286  46.257  51.836 1.00 9.49  ?  61   LEU B CD2  1 
ATOM   6538  H H    . LEU B 1 95  ? -14.279 47.174  50.488 1.00 10.76 ?  61   LEU B H    1 
ATOM   6539  H HA   . LEU B 1 95  ? -12.038 48.323  49.488 1.00 10.79 ?  61   LEU B HA   1 
ATOM   6540  H HB2  . LEU B 1 95  ? -11.468 47.755  51.697 1.00 10.93 ?  61   LEU B HB2  1 
ATOM   6541  H HB3  . LEU B 1 95  ? -11.867 46.248  51.388 1.00 10.93 ?  61   LEU B HB3  1 
ATOM   6542  H HG   . LEU B 1 95  ? -10.060 46.060  49.964 1.00 10.51 ?  61   LEU B HG   1 
ATOM   6543  H HD11 . LEU B 1 95  ? -8.442  47.775  49.855 1.00 12.79 ?  61   LEU B HD11 1 
ATOM   6544  H HD12 . LEU B 1 95  ? -9.810  48.175  49.154 1.00 12.79 ?  61   LEU B HD12 1 
ATOM   6545  H HD13 . LEU B 1 95  ? -9.465  48.736  50.600 1.00 12.79 ?  61   LEU B HD13 1 
ATOM   6546  H HD21 . LEU B 1 95  ? -8.390  46.015  51.555 1.00 11.39 ?  61   LEU B HD21 1 
ATOM   6547  H HD22 . LEU B 1 95  ? -9.246  46.960  52.504 1.00 11.39 ?  61   LEU B HD22 1 
ATOM   6548  H HD23 . LEU B 1 95  ? -9.739  45.481  52.200 1.00 11.39 ?  61   LEU B HD23 1 
ATOM   6549  N N    . ILE B 1 96  ? -12.135 46.737  47.637 1.00 8.58  ?  62   ILE B N    1 
ATOM   6550  C CA   . ILE B 1 96  ? -12.303 45.871  46.475 1.00 7.63  ?  62   ILE B CA   1 
ATOM   6551  C C    . ILE B 1 96  ? -10.944 45.690  45.826 1.00 7.85  ?  62   ILE B C    1 
ATOM   6552  O O    . ILE B 1 96  ? -10.275 46.678  45.511 1.00 9.19  ?  62   ILE B O    1 
ATOM   6553  C CB   . ILE B 1 96  ? -13.257 46.489  45.431 1.00 8.39  ?  62   ILE B CB   1 
ATOM   6554  C CG1  . ILE B 1 96  ? -14.584 46.840  46.073 1.00 9.35  ?  62   ILE B CG1  1 
ATOM   6555  C CG2  . ILE B 1 96  ? -13.441 45.537  44.256 1.00 10.38 ?  62   ILE B CG2  1 
ATOM   6556  C CD1  . ILE B 1 96  ? -14.893 48.303  45.992 1.00 13.94 ?  62   ILE B CD1  1 
ATOM   6557  H H    . ILE B 1 96  ? -11.684 47.447  47.458 1.00 10.29 ?  62   ILE B H    1 
ATOM   6558  H HA   . ILE B 1 96  ? -12.652 45.016  46.771 1.00 9.16  ?  62   ILE B HA   1 
ATOM   6559  H HB   . ILE B 1 96  ? -12.865 47.309  45.094 1.00 10.06 ?  62   ILE B HB   1 
ATOM   6560  H HG12 . ILE B 1 96  ? -15.293 46.357  45.619 1.00 11.21 ?  62   ILE B HG12 1 
ATOM   6561  H HG13 . ILE B 1 96  ? -14.559 46.588  47.010 1.00 11.21 ?  62   ILE B HG13 1 
ATOM   6562  H HG21 . ILE B 1 96  ? -14.173 45.853  43.704 1.00 12.45 ?  62   ILE B HG21 1 
ATOM   6563  H HG22 . ILE B 1 96  ? -12.622 45.514  43.737 1.00 12.45 ?  62   ILE B HG22 1 
ATOM   6564  H HG23 . ILE B 1 96  ? -13.642 44.650  44.596 1.00 12.45 ?  62   ILE B HG23 1 
ATOM   6565  H HD11 . ILE B 1 96  ? -15.721 48.477  46.467 1.00 16.72 ?  62   ILE B HD11 1 
ATOM   6566  H HD12 . ILE B 1 96  ? -14.167 48.801  46.399 1.00 16.72 ?  62   ILE B HD12 1 
ATOM   6567  H HD13 . ILE B 1 96  ? -14.986 48.555  45.060 1.00 16.72 ?  62   ILE B HD13 1 
ATOM   6568  N N    . THR B 1 97  ? -10.537 44.432  45.586 1.00 7.64  ?  63   THR B N    1 
ATOM   6569  C CA   . THR B 1 97  ? -9.389  44.135  44.732 1.00 7.49  ?  63   THR B CA   1 
ATOM   6570  C C    . THR B 1 97  ? -9.889  43.698  43.368 1.00 7.24  ?  63   THR B C    1 
ATOM   6571  O O    . THR B 1 97  ? -10.691 42.761  43.266 1.00 7.85  ?  63   THR B O    1 
ATOM   6572  C CB   . THR B 1 97  ? -8.494  43.045  45.328 1.00 8.15  ?  63   THR B CB   1 
ATOM   6573  O OG1  . THR B 1 97  ? -7.915  43.545  46.533 1.00 8.97  ?  63   THR B OG1  1 
ATOM   6574  C CG2  . THR B 1 97  ? -7.376  42.648  44.388 1.00 7.87  ?  63   THR B CG2  1 
ATOM   6575  H H    . THR B 1 97  ? -10.917 43.734  45.913 1.00 9.16  ?  63   THR B H    1 
ATOM   6576  H HA   . THR B 1 97  ? -8.851  44.936  44.638 1.00 8.99  ?  63   THR B HA   1 
ATOM   6577  H HB   . THR B 1 97  ? -9.031  42.254  45.495 1.00 9.78  ?  63   THR B HB   1 
ATOM   6578  H HG1  . THR B 1 97  ? -8.504  43.617  47.127 1.00 10.76 ?  63   THR B HG1  1 
ATOM   6579  H HG21 . THR B 1 97  ? -6.787  42.011  44.822 1.00 9.45  ?  63   THR B HG21 1 
ATOM   6580  H HG22 . THR B 1 97  ? -7.743  42.241  43.588 1.00 9.45  ?  63   THR B HG22 1 
ATOM   6581  H HG23 . THR B 1 97  ? -6.861  43.430  44.135 1.00 9.45  ?  63   THR B HG23 1 
ATOM   6582  N N    . LEU B 1 98  ? -9.401  44.375  42.334 1.00 7.00  ?  64   LEU B N    1 
ATOM   6583  C CA   . LEU B 1 98  ? -9.642  43.973  40.955 1.00 7.13  ?  64   LEU B CA   1 
ATOM   6584  C C    . LEU B 1 98  ? -8.505  43.051  40.523 1.00 7.21  ?  64   LEU B C    1 
ATOM   6585  O O    . LEU B 1 98  ? -7.337  43.469  40.445 1.00 7.55  ?  64   LEU B O    1 
ATOM   6586  C CB   . LEU B 1 98  ? -9.743  45.196  40.050 1.00 8.12  ?  64   LEU B CB   1 
ATOM   6587  C CG   . LEU B 1 98  ? -10.884 46.154  40.394 1.00 7.96  ?  64   LEU B CG   1 
ATOM   6588  C CD1  . LEU B 1 98  ? -10.832 47.372  39.488 1.00 9.66  ?  64   LEU B CD1  1 
ATOM   6589  C CD2  . LEU B 1 98  ? -12.232 45.464  40.343 1.00 8.17  ?  64   LEU B CD2  1 
ATOM   6590  H H    . LEU B 1 98  ? -8.919  45.083  42.407 1.00 8.40  ?  64   LEU B H    1 
ATOM   6591  H HA   . LEU B 1 98  ? -10.477 43.484  40.895 1.00 8.56  ?  64   LEU B HA   1 
ATOM   6592  H HB2  . LEU B 1 98  ? -8.914  45.695  40.112 1.00 9.74  ?  64   LEU B HB2  1 
ATOM   6593  H HB3  . LEU B 1 98  ? -9.880  44.893  39.138 1.00 9.74  ?  64   LEU B HB3  1 
ATOM   6594  H HG   . LEU B 1 98  ? -10.775 46.458  41.308 1.00 9.55  ?  64   LEU B HG   1 
ATOM   6595  H HD11 . LEU B 1 98  ? -11.452 48.040  39.821 1.00 11.60 ?  64   LEU B HD11 1 
ATOM   6596  H HD12 . LEU B 1 98  ? -9.930  47.728  39.488 1.00 11.60 ?  64   LEU B HD12 1 
ATOM   6597  H HD13 . LEU B 1 98  ? -11.083 47.107  38.589 1.00 11.60 ?  64   LEU B HD13 1 
ATOM   6598  H HD21 . LEU B 1 98  ? -12.925 46.110  40.549 1.00 9.80  ?  64   LEU B HD21 1 
ATOM   6599  H HD22 . LEU B 1 98  ? -12.369 45.104  39.452 1.00 9.80  ?  64   LEU B HD22 1 
ATOM   6600  H HD23 . LEU B 1 98  ? -12.244 44.746  40.995 1.00 9.80  ?  64   LEU B HD23 1 
ATOM   6601  N N    . GLU B 1 99  ? -8.860  41.794  40.261 1.00 6.95  ?  65   GLU B N    1 
ATOM   6602  C CA   . GLU B 1 99  ? -7.936  40.750  39.872 1.00 6.15  ?  65   GLU B CA   1 
ATOM   6603  C C    . GLU B 1 99  ? -7.415  40.956  38.456 1.00 6.93  ?  65   GLU B C    1 
ATOM   6604  O O    . GLU B 1 99  ? -7.844  41.849  37.714 1.00 7.94  ?  65   GLU B O    1 
ATOM   6605  C CB   . GLU B 1 99  ? -8.646  39.401  39.934 1.00 7.40  ?  65   GLU B CB   1 
ATOM   6606  C CG   . GLU B 1 99  ? -8.365  38.605  41.198 1.00 7.19  ?  65   GLU B CG   1 
ATOM   6607  C CD   . GLU B 1 99  ? -7.010  37.955  41.234 1.00 7.34  ?  65   GLU B CD   1 
ATOM   6608  O OE1  . GLU B 1 99  ? -6.304  37.972  40.204 1.00 7.51  ?  65   GLU B OE1  1 
ATOM   6609  O OE2  . GLU B 1 99  ? -6.679  37.452  42.325 1.00 8.07  ?  65   GLU B OE2  1 
ATOM   6610  H H    . GLU B 1 99  ? -9.672  41.513  40.304 1.00 8.34  ?  65   GLU B H    1 
ATOM   6611  H HA   . GLU B 1 99  ? -7.179  40.767  40.478 1.00 7.38  ?  65   GLU B HA   1 
ATOM   6612  H HB2  . GLU B 1 99  ? -9.603  39.553  39.888 1.00 8.89  ?  65   GLU B HB2  1 
ATOM   6613  H HB3  . GLU B 1 99  ? -8.358  38.865  39.179 1.00 8.89  ?  65   GLU B HB3  1 
ATOM   6614  H HG2  . GLU B 1 99  ? -8.424  39.202  41.960 1.00 8.62  ?  65   GLU B HG2  1 
ATOM   6615  H HG3  . GLU B 1 99  ? -9.029  37.902  41.276 1.00 8.62  ?  65   GLU B HG3  1 
ATOM   6616  N N    . LYS B 1 100 ? -6.449  40.114  38.095 1.00 7.12  ?  66   LYS B N    1 
ATOM   6617  C CA   . LYS B 1 100 ? -6.004  39.965  36.726 1.00 7.24  ?  66   LYS B CA   1 
ATOM   6618  C C    . LYS B 1 100 ? -7.183  39.567  35.827 1.00 7.55  ?  66   LYS B C    1 
ATOM   6619  O O    . LYS B 1 100 ? -8.251  39.180  36.281 1.00 7.25  ?  66   LYS B O    1 
ATOM   6620  C CB   . LYS B 1 100 ? -4.917  38.895  36.655 1.00 8.24  ?  66   LYS B CB   1 
ATOM   6621  C CG   . LYS B 1 100 ? -5.375  37.526  37.081 1.00 9.40  ?  66   LYS B CG   1 
ATOM   6622  C CD   . LYS B 1 100 ? -4.179  36.579  37.251 1.00 11.29 ?  66   LYS B CD   1 
ATOM   6623  C CE   . LYS B 1 100 ? -4.428  35.446  38.206 1.00 12.00 ?  66   LYS B CE   1 
ATOM   6624  N NZ   . LYS B 1 100 ? -4.632  35.797  39.645 1.00 8.20  ?  66   LYS B NZ   1 
ATOM   6625  H H    . LYS B 1 100 ? -6.025  39.606  38.645 1.00 8.54  ?  66   LYS B H    1 
ATOM   6626  H HA   . LYS B 1 100 ? -5.642  40.805  36.404 1.00 8.69  ?  66   LYS B HA   1 
ATOM   6627  H HB2  . LYS B 1 100 ? -4.604  38.829  35.740 1.00 9.88  ?  66   LYS B HB2  1 
ATOM   6628  H HB3  . LYS B 1 100 ? -4.186  39.155  37.238 1.00 9.88  ?  66   LYS B HB3  1 
ATOM   6629  H HG2  . LYS B 1 100 ? -5.841  37.589  37.930 1.00 11.28 ?  66   LYS B HG2  1 
ATOM   6630  H HG3  . LYS B 1 100 ? -5.966  37.157  36.406 1.00 11.28 ?  66   LYS B HG3  1 
ATOM   6631  H HD2  . LYS B 1 100 ? -3.961  36.194  36.388 1.00 13.55 ?  66   LYS B HD2  1 
ATOM   6632  H HD3  . LYS B 1 100 ? -3.425  37.087  37.589 1.00 13.55 ?  66   LYS B HD3  1 
ATOM   6633  H HE2  . LYS B 1 100 ? -5.227  34.979  37.915 1.00 14.40 ?  66   LYS B HE2  1 
ATOM   6634  H HE3  . LYS B 1 100 ? -3.664  34.850  38.168 1.00 14.40 ?  66   LYS B HE3  1 
ATOM   6635  H HZ1  . LYS B 1 100 ? -4.864  35.072  40.106 1.00 9.84  ?  66   LYS B HZ1  1 
ATOM   6636  H HZ2  . LYS B 1 100 ? -3.881  36.129  39.987 1.00 9.84  ?  66   LYS B HZ2  1 
ATOM   6637  H HZ3  . LYS B 1 100 ? -5.278  36.406  39.721 1.00 9.84  ?  66   LYS B HZ3  1 
ATOM   6638  N N    . SER B 1 101 ? -6.957  39.668  34.520 1.00 7.11  ?  67   SER B N    1 
ATOM   6639  C CA   . SER B 1 101 ? -7.992  39.425  33.516 1.00 7.01  ?  67   SER B CA   1 
ATOM   6640  C C    . SER B 1 101 ? -9.261  40.217  33.849 1.00 7.68  ?  67   SER B C    1 
ATOM   6641  O O    . SER B 1 101 ? -10.346 39.694  34.103 1.00 7.47  ?  67   SER B O    1 
ATOM   6642  C CB   . SER B 1 101 ? -8.268  37.943  33.318 1.00 7.96  ?  67   SER B CB   1 
ATOM   6643  O OG   . SER B 1 101 ? -7.187  37.311  32.656 1.00 9.29  ?  67   SER B OG   1 
ATOM   6644  H H    . SER B 1 101 ? -6.195  39.880  34.181 1.00 8.53  ?  67   SER B H    1 
ATOM   6645  H HA   . SER B 1 101 ? -7.663  39.750  32.663 1.00 8.42  ?  67   SER B HA   1 
ATOM   6646  H HB2  . SER B 1 101 ? -8.393  37.527  34.185 1.00 9.55  ?  67   SER B HB2  1 
ATOM   6647  H HB3  . SER B 1 101 ? -9.070  37.840  32.782 1.00 9.55  ?  67   SER B HB3  1 
ATOM   6648  H HG   . SER B 1 101 ? -6.469  37.468  33.063 1.00 11.15 ?  67   SER B HG   1 
ATOM   6649  N N    . GLN B 1 102 ? -9.091  41.534  33.845 1.00 7.23  ?  68   GLN B N    1 
ATOM   6650  C CA   . GLN B 1 102 ? -10.142 42.456  34.291 1.00 7.27  ?  68   GLN B CA   1 
ATOM   6651  C C    . GLN B 1 102 ? -10.857 43.043  33.088 1.00 7.97  ?  68   GLN B C    1 
ATOM   6652  O O    . GLN B 1 102 ? -10.419 44.056  32.524 1.00 8.34  ?  68   GLN B O    1 
ATOM   6653  C CB   . GLN B 1 102 ? -9.550  43.546  35.175 1.00 7.88  ?  68   GLN B CB   1 
ATOM   6654  C CG   . GLN B 1 102 ? -10.579 44.290  36.019 1.00 7.93  ?  68   GLN B CG   1 
ATOM   6655  C CD   . GLN B 1 102 ? -11.351 43.408  36.982 1.00 7.58  ?  68   GLN B CD   1 
ATOM   6656  O OE1  . GLN B 1 102 ? -12.576 43.496  37.085 1.00 9.10  ?  68   GLN B OE1  1 
ATOM   6657  N NE2  . GLN B 1 102 ? -10.637 42.564  37.719 1.00 8.28  ?  68   GLN B NE2  1 
ATOM   6658  H H    . GLN B 1 102 ? -8.370  41.926  33.586 1.00 8.67  ?  68   GLN B H    1 
ATOM   6659  H HA   . GLN B 1 102 ? -10.798 41.951  34.797 1.00 8.73  ?  68   GLN B HA   1 
ATOM   6660  H HB2  . GLN B 1 102 ? -8.910  43.141  35.781 1.00 9.45  ?  68   GLN B HB2  1 
ATOM   6661  H HB3  . GLN B 1 102 ? -9.106  44.197  34.610 1.00 9.45  ?  68   GLN B HB3  1 
ATOM   6662  H HG2  . GLN B 1 102 ? -10.121 44.966  36.543 1.00 9.51  ?  68   GLN B HG2  1 
ATOM   6663  H HG3  . GLN B 1 102 ? -11.222 44.710  35.426 1.00 9.51  ?  68   GLN B HG3  1 
ATOM   6664  H HE21 . GLN B 1 102 ? -9.781  42.538  37.636 1.00 9.94  ?  68   GLN B HE21 1 
ATOM   6665  H HE22 . GLN B 1 102 ? -11.030 42.043  38.280 1.00 9.94  ?  68   GLN B HE22 1 
ATOM   6666  N N    . ALA B 1 103 ? -11.975 42.414  32.721 1.00 7.57  ?  69   ALA B N    1 
ATOM   6667  C CA   . ALA B 1 103 ? -12.854 42.876  31.635 1.00 7.72  ?  69   ALA B CA   1 
ATOM   6668  C C    . ALA B 1 103 ? -12.109 43.065  30.321 1.00 9.59  ?  69   ALA B C    1 
ATOM   6669  O O    . ALA B 1 103 ? -12.466 43.923  29.494 1.00 9.84  ?  69   ALA B O    1 
ATOM   6670  C CB   . ALA B 1 103 ? -13.599 44.139  32.053 1.00 9.13  ?  69   ALA B CB   1 
ATOM   6671  H H    . ALA B 1 103 ? -12.258 41.693  33.095 1.00 9.08  ?  69   ALA B H    1 
ATOM   6672  H HA   . ALA B 1 103 ? -13.513 42.186  31.461 1.00 9.26  ?  69   ALA B HA   1 
ATOM   6673  H HB1  . ALA B 1 103 ? -14.187 44.412  31.332 1.00 10.96 ?  69   ALA B HB1  1 
ATOM   6674  H HB2  . ALA B 1 103 ? -14.118 43.949  32.850 1.00 10.96 ?  69   ALA B HB2  1 
ATOM   6675  H HB3  . ALA B 1 103 ? -12.954 44.839  32.238 1.00 10.96 ?  69   ALA B HB3  1 
ATOM   6676  N N    . GLN B 1 104 ? -11.123 42.213  30.066 1.00 10.29 ?  70   GLN B N    1 
ATOM   6677  C CA   . GLN B 1 104 ? -10.257 42.393  28.913 1.00 9.57  ?  70   GLN B CA   1 
ATOM   6678  C C    . GLN B 1 104 ? -10.958 42.107  27.594 1.00 10.05 ?  70   GLN B C    1 
ATOM   6679  O O    . GLN B 1 104 ? -10.486 42.583  26.551 1.00 11.99 ?  70   GLN B O    1 
ATOM   6680  C CB   . GLN B 1 104 ? -9.000  41.513  29.042 1.00 9.86  ?  70   GLN B CB   1 
ATOM   6681  C CG   . GLN B 1 104 ? -9.194  40.034  28.724 1.00 9.31  ?  70   GLN B CG   1 
ATOM   6682  C CD   . GLN B 1 104 ? -9.940  39.278  29.799 1.00 9.91  ?  70   GLN B CD   1 
ATOM   6683  O OE1  . GLN B 1 104 ? -10.035 39.726  30.940 1.00 9.66  ?  70   GLN B OE1  1 
ATOM   6684  N NE2  . GLN B 1 104 ? -10.439 38.105  29.458 1.00 11.35 ?  70   GLN B NE2  1 
ATOM   6685  H H    . GLN B 1 104 ? -10.937 41.523  30.545 1.00 12.35 ?  70   GLN B H    1 
ATOM   6686  H HA   . GLN B 1 104 ? -9.970  43.320  28.896 1.00 11.48 ?  70   GLN B HA   1 
ATOM   6687  H HB2  . GLN B 1 104 ? -8.327  41.852  28.432 1.00 11.83 ?  70   GLN B HB2  1 
ATOM   6688  H HB3  . GLN B 1 104 ? -8.680  41.571  29.956 1.00 11.83 ?  70   GLN B HB3  1 
ATOM   6689  H HG2  . GLN B 1 104 ? -9.700  39.955  27.900 1.00 11.17 ?  70   GLN B HG2  1 
ATOM   6690  H HG3  . GLN B 1 104 ? -8.323  39.620  28.620 1.00 11.17 ?  70   GLN B HG3  1 
ATOM   6691  H HE21 . GLN B 1 104 ? -10.331 37.808  28.658 1.00 13.62 ?  70   GLN B HE21 1 
ATOM   6692  H HE22 . GLN B 1 104 ? -10.872 37.637  30.035 1.00 13.62 ?  70   GLN B HE22 1 
ATOM   6693  N N    . ASN B 1 105 ? -12.048 41.353  27.607 1.00 9.42  ?  71   ASN B N    1 
ATOM   6694  C CA   . ASN B 1 105 ? -12.759 41.069  26.369 1.00 11.43 ?  71   ASN B CA   1 
ATOM   6695  C C    . ASN B 1 105 ? -13.763 42.151  26.012 1.00 13.68 ?  71   ASN B C    1 
ATOM   6696  O O    . ASN B 1 105 ? -14.381 42.074  24.945 1.00 17.72 ?  71   ASN B O    1 
ATOM   6697  C CB   . ASN B 1 105 ? -13.423 39.689  26.417 1.00 11.40 ?  71   ASN B CB   1 
ATOM   6698  C CG   . ASN B 1 105 ? -12.408 38.559  26.446 1.00 11.98 ?  71   ASN B CG   1 
ATOM   6699  O OD1  . ASN B 1 105 ? -11.222 38.770  26.185 1.00 13.51 ?  71   ASN B OD1  1 
ATOM   6700  N ND2  . ASN B 1 105 ? -12.865 37.371  26.792 1.00 14.39 ?  71   ASN B ND2  1 
ATOM   6701  H H    . ASN B 1 105 ? -12.391 41.000  28.311 1.00 11.31 ?  71   ASN B H    1 
ATOM   6702  H HA   . ASN B 1 105 ? -12.116 41.025  25.644 1.00 13.71 ?  71   ASN B HA   1 
ATOM   6703  H HB2  . ASN B 1 105 ? -13.967 39.626  27.218 1.00 13.68 ?  71   ASN B HB2  1 
ATOM   6704  H HB3  . ASN B 1 105 ? -13.977 39.576  25.630 1.00 13.68 ?  71   ASN B HB3  1 
ATOM   6705  H HD21 . ASN B 1 105 ? -12.331 36.698  26.824 1.00 17.27 ?  71   ASN B HD21 1 
ATOM   6706  H HD22 . ASN B 1 105 ? -13.697 37.270  26.985 1.00 17.27 ?  71   ASN B HD22 1 
ATOM   6707  N N    . THR B 1 106 ? -13.920 43.167  26.853 1.00 9.83  ?  72   THR B N    1 
ATOM   6708  C CA   . THR B 1 106 ? -14.624 44.389  26.494 1.00 11.09 ?  72   THR B CA   1 
ATOM   6709  C C    . THR B 1 106 ? -13.665 45.530  26.178 1.00 10.82 ?  72   THR B C    1 
ATOM   6710  O O    . THR B 1 106 ? -13.864 46.259  25.196 1.00 12.38 ?  72   THR B O    1 
ATOM   6711  C CB   . THR B 1 106 ? -15.551 44.813  27.635 1.00 9.28  ?  72   THR B CB   1 
ATOM   6712  O OG1  . THR B 1 106 ? -16.512 43.798  27.892 1.00 11.08 ?  72   THR B OG1  1 
ATOM   6713  C CG2  . THR B 1 106 ? -16.251 46.154  27.278 1.00 10.68 ?  72   THR B CG2  1 
ATOM   6714  H H    . THR B 1 106 ? -13.620 43.172  27.659 1.00 11.79 ?  72   THR B H    1 
ATOM   6715  H HA   . THR B 1 106 ? -15.173 44.225  25.711 1.00 13.31 ?  72   THR B HA   1 
ATOM   6716  H HB   . THR B 1 106 ? -15.037 44.948  28.446 1.00 11.13 ?  72   THR B HB   1 
ATOM   6717  H HG1  . THR B 1 106 ? -17.057 43.751  27.255 1.00 13.30 ?  72   THR B HG1  1 
ATOM   6718  H HG21 . THR B 1 106 ? -16.957 46.340  27.916 1.00 12.82 ?  72   THR B HG21 1 
ATOM   6719  H HG22 . THR B 1 106 ? -15.607 46.880  27.300 1.00 12.82 ?  72   THR B HG22 1 
ATOM   6720  H HG23 . THR B 1 106 ? -16.636 46.101  26.389 1.00 12.82 ?  72   THR B HG23 1 
ATOM   6721  N N    . TYR B 1 107 ? -12.621 45.705  26.982 1.00 10.18 ?  73   TYR B N    1 
ATOM   6722  C CA   . TYR B 1 107 ? -11.752 46.870  26.914 1.00 11.09 ?  73   TYR B CA   1 
ATOM   6723  C C    . TYR B 1 107 ? -10.415 46.586  26.250 1.00 9.73  ?  73   TYR B C    1 
ATOM   6724  O O    . TYR B 1 107 ? -9.613  47.510  26.105 1.00 13.34 ?  73   TYR B O    1 
ATOM   6725  C CB   . TYR B 1 107 ? -11.556 47.459  28.326 1.00 11.18 ?  73   TYR B CB   1 
ATOM   6726  C CG   . TYR B 1 107 ? -12.865 47.905  28.916 1.00 8.78  ?  73   TYR B CG   1 
ATOM   6727  C CD1  . TYR B 1 107 ? -13.460 49.109  28.507 1.00 10.53 ?  73   TYR B CD1  1 
ATOM   6728  C CD2  . TYR B 1 107 ? -13.538 47.134  29.861 1.00 10.63 ?  73   TYR B CD2  1 
ATOM   6729  C CE1  . TYR B 1 107 ? -14.674 49.507  29.021 1.00 11.08 ?  73   TYR B CE1  1 
ATOM   6730  C CE2  . TYR B 1 107 ? -14.755 47.525  30.380 1.00 10.04 ?  73   TYR B CE2  1 
ATOM   6731  C CZ   . TYR B 1 107 ? -15.325 48.718  29.941 1.00 12.26 ?  73   TYR B CZ   1 
ATOM   6732  O OH   . TYR B 1 107 ? -16.543 49.125  30.438 1.00 13.53 ?  73   TYR B OH   1 
ATOM   6733  H H    . TYR B 1 107 ? -12.391 45.145  27.593 1.00 12.21 ?  73   TYR B H    1 
ATOM   6734  H HA   . TYR B 1 107 ? -12.183 47.552  26.376 1.00 13.31 ?  73   TYR B HA   1 
ATOM   6735  H HB2  . TYR B 1 107 ? -11.172 46.783  28.906 1.00 13.41 ?  73   TYR B HB2  1 
ATOM   6736  H HB3  . TYR B 1 107 ? -10.965 48.227  28.275 1.00 13.41 ?  73   TYR B HB3  1 
ATOM   6737  H HD1  . TYR B 1 107 ? -13.029 49.645  27.881 1.00 12.63 ?  73   TYR B HD1  1 
ATOM   6738  H HD2  . TYR B 1 107 ? -13.158 46.335  30.149 1.00 12.75 ?  73   TYR B HD2  1 
ATOM   6739  H HE1  . TYR B 1 107 ? -15.054 50.310  28.745 1.00 13.29 ?  73   TYR B HE1  1 
ATOM   6740  H HE2  . TYR B 1 107 ? -15.188 47.000  31.013 1.00 12.05 ?  73   TYR B HE2  1 
ATOM   6741  H HH   . TYR B 1 107 ? -16.776 48.626  31.072 1.00 16.24 ?  73   TYR B HH   1 
ATOM   6742  N N    . GLY B 1 108 ? -10.171 45.350  25.833 1.00 10.56 ?  74   GLY B N    1 
ATOM   6743  C CA   . GLY B 1 108 ? -8.969  44.989  25.109 1.00 11.11 ?  74   GLY B CA   1 
ATOM   6744  C C    . GLY B 1 108 ? -7.790  44.571  25.959 1.00 12.52 ?  74   GLY B C    1 
ATOM   6745  O O    . GLY B 1 108 ? -6.843  43.973  25.428 1.00 14.50 ?  74   GLY B O    1 
ATOM   6746  H H    . GLY B 1 108 ? -10.704 44.687  25.962 1.00 12.67 ?  74   GLY B H    1 
ATOM   6747  H HA2  . GLY B 1 108 ? -9.177  44.251  24.516 1.00 13.33 ?  74   GLY B HA2  1 
ATOM   6748  H HA3  . GLY B 1 108 ? -8.690  45.752  24.579 1.00 13.33 ?  74   GLY B HA3  1 
ATOM   6749  N N    . SER B 1 109 ? -7.810  44.859  27.255 1.00 10.10 ?  75   SER B N    1 
ATOM   6750  C CA   . SER B 1 109 ? -6.683  44.599  28.129 1.00 9.64  ?  75   SER B CA   1 
ATOM   6751  C C    . SER B 1 109 ? -7.154  44.744  29.565 1.00 9.91  ?  75   SER B C    1 
ATOM   6752  O O    . SER B 1 109 ? -8.131  45.439  29.851 1.00 9.76  ?  75   SER B O    1 
ATOM   6753  C CB   . SER B 1 109 ? -5.529  45.563  27.879 1.00 10.53 ?  75   SER B CB   1 
ATOM   6754  O OG   . SER B 1 109 ? -5.868  46.895  28.221 1.00 11.55 ?  75   SER B OG   1 
ATOM   6755  H H    . SER B 1 109 ? -8.482  45.214  27.657 1.00 12.12 ?  75   SER B H    1 
ATOM   6756  H HA   . SER B 1 109 ? -6.372  43.693  27.979 1.00 11.57 ?  75   SER B HA   1 
ATOM   6757  H HB2  . SER B 1 109 ? -4.771  45.287  28.417 1.00 12.63 ?  75   SER B HB2  1 
ATOM   6758  H HB3  . SER B 1 109 ? -5.297  45.532  26.938 1.00 12.63 ?  75   SER B HB3  1 
ATOM   6759  H HG   . SER B 1 109 ? -6.467  47.181  27.706 1.00 13.86 ?  75   SER B HG   1 
ATOM   6760  N N    . THR B 1 110 ? -6.418  44.106  30.470 1.00 8.67  ?  76   THR B N    1 
ATOM   6761  C CA   . THR B 1 110 ? -6.674  44.299  31.896 1.00 8.25  ?  76   THR B CA   1 
ATOM   6762  C C    . THR B 1 110 ? -6.392  45.728  32.323 1.00 8.99  ?  76   THR B C    1 
ATOM   6763  O O    . THR B 1 110 ? -7.093  46.263  33.195 1.00 8.79  ?  76   THR B O    1 
ATOM   6764  C CB   . THR B 1 110 ? -5.830  43.312  32.683 1.00 8.29  ?  76   THR B CB   1 
ATOM   6765  O OG1  . THR B 1 110 ? -6.413  42.030  32.451 1.00 8.44  ?  76   THR B OG1  1 
ATOM   6766  C CG2  . THR B 1 110 ? -5.807  43.618  34.158 1.00 8.30  ?  76   THR B CG2  1 
ATOM   6767  H H    . THR B 1 110 ? -5.774  43.565  30.290 1.00 10.40 ?  76   THR B H    1 
ATOM   6768  H HA   . THR B 1 110 ? -7.609  44.125  32.087 1.00 9.90  ?  76   THR B HA   1 
ATOM   6769  H HB   . THR B 1 110 ? -4.901  43.346  32.404 1.00 9.95  ?  76   THR B HB   1 
ATOM   6770  H HG1  . THR B 1 110 ? -5.839  41.428  32.570 1.00 10.13 ?  76   THR B HG1  1 
ATOM   6771  H HG21 . THR B 1 110 ? -5.324  42.924  34.633 1.00 9.96  ?  76   THR B HG21 1 
ATOM   6772  H HG22 . THR B 1 110 ? -5.370  44.470  34.313 1.00 9.96  ?  76   THR B HG22 1 
ATOM   6773  H HG23 . THR B 1 110 ? -6.713  43.662  34.501 1.00 9.96  ?  76   THR B HG23 1 
ATOM   6774  N N    . GLU B 1 111 ? -5.376  46.367  31.738 1.00 9.05  ?  77   GLU B N    1 
ATOM   6775  C CA   . GLU B 1 111 ? -5.069  47.737  32.141 1.00 9.19  ?  77   GLU B CA   1 
ATOM   6776  C C    . GLU B 1 111 ? -6.267  48.648  31.883 1.00 9.55  ?  77   GLU B C    1 
ATOM   6777  O O    . GLU B 1 111 ? -6.720  49.378  32.777 1.00 9.62  ?  77   GLU B O    1 
ATOM   6778  C CB   . GLU B 1 111 ? -3.807  48.242  31.437 1.00 9.61  ?  77   GLU B CB   1 
ATOM   6779  C CG   . GLU B 1 111 ? -2.521  47.489  31.778 1.00 10.25 ?  77   GLU B CG   1 
ATOM   6780  C CD   . GLU B 1 111 ? -2.206  46.335  30.818 1.00 10.24 ?  77   GLU B CD   1 
ATOM   6781  O OE1  . GLU B 1 111 ? -3.146  45.773  30.223 1.00 9.25  ?  77   GLU B OE1  1 
ATOM   6782  O OE2  . GLU B 1 111 ? -0.994  46.013  30.675 1.00 9.50  ?  77   GLU B OE2  1 
ATOM   6783  H H    . GLU B 1 111 ? -4.867  46.040  31.127 1.00 10.86 ?  77   GLU B H    1 
ATOM   6784  H HA   . GLU B 1 111 ? -4.877  47.755  33.092 1.00 11.03 ?  77   GLU B HA   1 
ATOM   6785  H HB2  . GLU B 1 111 ? -3.940  48.167  30.479 1.00 11.53 ?  77   GLU B HB2  1 
ATOM   6786  H HB3  . GLU B 1 111 ? -3.671  49.171  31.681 1.00 11.53 ?  77   GLU B HB3  1 
ATOM   6787  H HG2  . GLU B 1 111 ? -1.778  48.111  31.747 1.00 12.30 ?  77   GLU B HG2  1 
ATOM   6788  H HG3  . GLU B 1 111 ? -2.605  47.116  32.670 1.00 12.30 ?  77   GLU B HG3  1 
ATOM   6789  N N    . GLU B 1 112 ? -6.835  48.583  30.682 1.00 9.41  ?  78   GLU B N    1 
ATOM   6790  C CA   . GLU B 1 112 ? -7.954  49.461  30.367 1.00 9.35  ?  78   GLU B CA   1 
ATOM   6791  C C    . GLU B 1 112 ? -9.249  48.984  31.011 1.00 8.89  ?  78   GLU B C    1 
ATOM   6792  O O    . GLU B 1 112 ? -10.091 49.815  31.377 1.00 10.49 ?  78   GLU B O    1 
ATOM   6793  C CB   . GLU B 1 112 ? -8.099  49.638  28.863 1.00 11.24 ?  78   GLU B CB   1 
ATOM   6794  C CG   . GLU B 1 112 ? -6.950  50.420  28.263 1.00 12.91 ?  78   GLU B CG   1 
ATOM   6795  C CD   . GLU B 1 112 ? -6.928  51.904  28.635 1.00 15.89 ?  78   GLU B CD   1 
ATOM   6796  O OE1  . GLU B 1 112 ? -8.009  52.510  28.800 1.00 16.48 ?  78   GLU B OE1  1 
ATOM   6797  O OE2  . GLU B 1 112 ? -5.804  52.445  28.784 1.00 21.98 ?  78   GLU B OE2  1 
ATOM   6798  H H    . GLU B 1 112 ? -6.597  48.052  30.049 1.00 11.29 ?  78   GLU B H    1 
ATOM   6799  H HA   . GLU B 1 112 ? -7.769  50.345  30.721 1.00 11.22 ?  78   GLU B HA   1 
ATOM   6800  H HB2  . GLU B 1 112 ? -8.122  48.765  28.442 1.00 13.48 ?  78   GLU B HB2  1 
ATOM   6801  H HB3  . GLU B 1 112 ? -8.921  50.118  28.678 1.00 13.48 ?  78   GLU B HB3  1 
ATOM   6802  H HG2  . GLU B 1 112 ? -6.117  50.030  28.568 1.00 15.49 ?  78   GLU B HG2  1 
ATOM   6803  H HG3  . GLU B 1 112 ? -7.009  50.363  27.296 1.00 15.49 ?  78   GLU B HG3  1 
ATOM   6804  N N    . GLY B 1 113 ? -9.444  47.673  31.179 1.00 8.59  ?  79   GLY B N    1 
ATOM   6805  C CA   . GLY B 1 113 ? -10.618 47.197  31.891 1.00 9.19  ?  79   GLY B CA   1 
ATOM   6806  C C    . GLY B 1 113 ? -10.617 47.589  33.359 1.00 8.67  ?  79   GLY B C    1 
ATOM   6807  O O    . GLY B 1 113 ? -11.670 47.874  33.941 1.00 9.36  ?  79   GLY B O    1 
ATOM   6808  H H    . GLY B 1 113 ? -8.919  47.055  30.894 1.00 10.31 ?  79   GLY B H    1 
ATOM   6809  H HA2  . GLY B 1 113 ? -11.414 47.568  31.478 1.00 11.03 ?  79   GLY B HA2  1 
ATOM   6810  H HA3  . GLY B 1 113 ? -10.655 46.230  31.835 1.00 11.03 ?  79   GLY B HA3  1 
ATOM   6811  N N    . THR B 1 114 ? -9.439  47.598  33.979 1.00 8.60  ?  80   THR B N    1 
ATOM   6812  C CA   . THR B 1 114 ? -9.303  48.078  35.351 1.00 8.94  ?  80   THR B CA   1 
ATOM   6813  C C    . THR B 1 114 ? -9.665  49.551  35.438 1.00 8.77  ?  80   THR B C    1 
ATOM   6814  O O    . THR B 1 114 ? -10.415 49.959  36.327 1.00 9.19  ?  80   THR B O    1 
ATOM   6815  C CB   . THR B 1 114 ? -7.858  47.854  35.804 1.00 7.77  ?  80   THR B CB   1 
ATOM   6816  O OG1  . THR B 1 114 ? -7.596  46.440  35.834 1.00 8.66  ?  80   THR B OG1  1 
ATOM   6817  C CG2  . THR B 1 114 ? -7.590  48.426  37.186 1.00 8.89  ?  80   THR B CG2  1 
ATOM   6818  H H    . THR B 1 114 ? -8.701  47.331  33.627 1.00 10.32 ?  80   THR B H    1 
ATOM   6819  H HA   . THR B 1 114 ? -9.899  47.585  35.937 1.00 10.73 ?  80   THR B HA   1 
ATOM   6820  H HB   . THR B 1 114 ? -7.265  48.306  35.184 1.00 9.32  ?  80   THR B HB   1 
ATOM   6821  H HG1  . THR B 1 114 ? -7.385  46.171  35.067 1.00 10.39 ?  80   THR B HG1  1 
ATOM   6822  H HG21 . THR B 1 114 ? -6.654  48.311  37.417 1.00 10.67 ?  80   THR B HG21 1 
ATOM   6823  H HG22 . THR B 1 114 ? -7.804  49.372  37.201 1.00 10.67 ?  80   THR B HG22 1 
ATOM   6824  H HG23 . THR B 1 114 ? -8.135  47.969  37.846 1.00 10.67 ?  80   THR B HG23 1 
ATOM   6825  N N    . LEU B 1 115 ? -9.132  50.368  34.525 1.00 8.45  ?  81   LEU B N    1 
ATOM   6826  C CA   . LEU B 1 115 ? -9.417  51.798  34.560 1.00 8.35  ?  81   LEU B CA   1 
ATOM   6827  C C    . LEU B 1 115 ? -10.906 52.063  34.379 1.00 9.39  ?  81   LEU B C    1 
ATOM   6828  O O    . LEU B 1 115 ? -11.489 52.869  35.113 1.00 9.00  ?  81   LEU B O    1 
ATOM   6829  C CB   . LEU B 1 115 ? -8.603  52.519  33.485 1.00 10.52 ?  81   LEU B CB   1 
ATOM   6830  C CG   . LEU B 1 115 ? -7.108  52.601  33.732 1.00 11.81 ?  81   LEU B CG   1 
ATOM   6831  C CD1  . LEU B 1 115 ? -6.394  53.134  32.510 1.00 16.21 ?  81   LEU B CD1  1 
ATOM   6832  C CD2  . LEU B 1 115 ? -6.783  53.452  34.943 1.00 10.63 ?  81   LEU B CD2  1 
ATOM   6833  H H    . LEU B 1 115 ? -8.612  50.121  33.886 1.00 10.14 ?  81   LEU B H    1 
ATOM   6834  H HA   . LEU B 1 115 ? -9.152  52.153  35.423 1.00 10.02 ?  81   LEU B HA   1 
ATOM   6835  H HB2  . LEU B 1 115 ? -8.731  52.053  32.645 1.00 12.62 ?  81   LEU B HB2  1 
ATOM   6836  H HB3  . LEU B 1 115 ? -8.933  53.429  33.414 1.00 12.62 ?  81   LEU B HB3  1 
ATOM   6837  H HG   . LEU B 1 115 ? -6.786  51.704  33.913 1.00 14.18 ?  81   LEU B HG   1 
ATOM   6838  H HD11 . LEU B 1 115 ? -5.447  53.206  32.704 1.00 19.45 ?  81   LEU B HD11 1 
ATOM   6839  H HD12 . LEU B 1 115 ? -6.535  52.523  31.770 1.00 19.45 ?  81   LEU B HD12 1 
ATOM   6840  H HD13 . LEU B 1 115 ? -6.754  54.008  32.290 1.00 19.45 ?  81   LEU B HD13 1 
ATOM   6841  H HD21 . LEU B 1 115 ? -5.821  53.567  34.998 1.00 12.76 ?  81   LEU B HD21 1 
ATOM   6842  H HD22 . LEU B 1 115 ? -7.214  54.316  34.846 1.00 12.76 ?  81   LEU B HD22 1 
ATOM   6843  H HD23 . LEU B 1 115 ? -7.109  53.006  35.740 1.00 12.76 ?  81   LEU B HD23 1 
ATOM   6844  N N    . ALA B 1 116 ? -11.561 51.346  33.468 1.00 8.80  ?  82   ALA B N    1 
ATOM   6845  C CA   . ALA B 1 116 ? -12.985 51.580  33.228 1.00 10.55 ?  82   ALA B CA   1 
ATOM   6846  C C    . ALA B 1 116 ? -13.803 51.162  34.439 1.00 9.85  ?  82   ALA B C    1 
ATOM   6847  O O    . ALA B 1 116 ? -14.725 51.868  34.878 1.00 9.94  ?  82   ALA B O    1 
ATOM   6848  C CB   . ALA B 1 116 ? -13.439 50.814  31.987 1.00 9.07  ?  82   ALA B CB   1 
ATOM   6849  H H    . ALA B 1 116 ? -11.212 50.728  32.982 1.00 10.56 ?  82   ALA B H    1 
ATOM   6850  H HA   . ALA B 1 116 ? -13.131 52.525  33.066 1.00 12.65 ?  82   ALA B HA   1 
ATOM   6851  H HB1  . ALA B 1 116 ? -14.395 50.933  31.875 1.00 10.88 ?  82   ALA B HB1  1 
ATOM   6852  H HB2  . ALA B 1 116 ? -12.969 51.161  31.212 1.00 10.88 ?  82   ALA B HB2  1 
ATOM   6853  H HB3  . ALA B 1 116 ? -13.234 49.873  32.104 1.00 10.88 ?  82   ALA B HB3  1 
ATOM   6854  N N    . THR B 1 117 ? -13.473 50.010  35.006 1.00 9.49  ?  83   THR B N    1 
ATOM   6855  C CA   . THR B 1 117 ? -14.234 49.490  36.134 1.00 8.97  ?  83   THR B CA   1 
ATOM   6856  C C    . THR B 1 117 ? -14.071 50.391  37.343 1.00 8.57  ?  83   THR B C    1 
ATOM   6857  O O    . THR B 1 117 ? -15.054 50.732  38.016 1.00 9.08  ?  83   THR B O    1 
ATOM   6858  C CB   . THR B 1 117 ? -13.748 48.067  36.451 1.00 8.61  ?  83   THR B CB   1 
ATOM   6859  O OG1  . THR B 1 117 ? -13.992 47.217  35.323 1.00 9.18  ?  83   THR B OG1  1 
ATOM   6860  C CG2  . THR B 1 117 ? -14.465 47.498  37.647 1.00 9.10  ?  83   THR B CG2  1 
ATOM   6861  H H    . THR B 1 117 ? -12.817 49.512  34.759 1.00 11.38 ?  83   THR B H    1 
ATOM   6862  H HA   . THR B 1 117 ? -15.176 49.452  35.909 1.00 10.76 ?  83   THR B HA   1 
ATOM   6863  H HB   . THR B 1 117 ? -12.799 48.097  36.651 1.00 10.33 ?  83   THR B HB   1 
ATOM   6864  H HG1  . THR B 1 117 ? -13.341 47.248  34.793 1.00 11.02 ?  83   THR B HG1  1 
ATOM   6865  H HG21 . THR B 1 117 ? -14.167 46.590  37.811 1.00 10.92 ?  83   THR B HG21 1 
ATOM   6866  H HG22 . THR B 1 117 ? -14.281 48.037  38.432 1.00 10.92 ?  83   THR B HG22 1 
ATOM   6867  H HG23 . THR B 1 117 ? -15.422 47.491  37.487 1.00 10.92 ?  83   THR B HG23 1 
ATOM   6868  N N    . ALA B 1 118 ? -12.831 50.786  37.638 1.00 8.35  ?  84   ALA B N    1 
ATOM   6869  C CA   . ALA B 1 118 ? -12.592 51.643  38.785 1.00 7.89  ?  84   ALA B CA   1 
ATOM   6870  C C    . ALA B 1 118 ? -13.303 52.978  38.635 1.00 10.59 ?  84   ALA B C    1 
ATOM   6871  O O    . ALA B 1 118 ? -13.843 53.506  39.613 1.00 8.67  ?  84   ALA B O    1 
ATOM   6872  C CB   . ALA B 1 118 ? -11.094 51.843  38.986 1.00 9.63  ?  84   ALA B CB   1 
ATOM   6873  H H    . ALA B 1 118 ? -12.126 50.572  37.194 1.00 10.02 ?  84   ALA B H    1 
ATOM   6874  H HA   . ALA B 1 118 ? -12.942 51.210  39.579 1.00 9.46  ?  84   ALA B HA   1 
ATOM   6875  H HB1  . ALA B 1 118 ? -10.953 52.434  39.742 1.00 11.55 ?  84   ALA B HB1  1 
ATOM   6876  H HB2  . ALA B 1 118 ? -10.681 50.982  39.158 1.00 11.55 ?  84   ALA B HB2  1 
ATOM   6877  H HB3  . ALA B 1 118 ? -10.717 52.236  38.184 1.00 11.55 ?  84   ALA B HB3  1 
ATOM   6878  N N    . SER B 1 119 ? -13.296 53.547  37.432 1.00 9.43  ?  85   SER B N    1 
ATOM   6879  C CA   . SER B 1 119 ? -13.954 54.838  37.243 1.00 9.60  ?  85   SER B CA   1 
ATOM   6880  C C    . SER B 1 119 ? -15.440 54.710  37.519 1.00 10.00 ?  85   SER B C    1 
ATOM   6881  O O    . SER B 1 119 ? -16.030 55.577  38.175 1.00 9.94  ?  85   SER B O    1 
ATOM   6882  C CB   . SER B 1 119 ? -13.705 55.328  35.824 1.00 10.16 ?  85   SER B CB   1 
ATOM   6883  O OG   . SER B 1 119 ? -14.301 56.616  35.624 1.00 12.06 ?  85   SER B OG   1 
ATOM   6884  H H    . SER B 1 119 ? -12.928 53.217  36.728 1.00 11.32 ?  85   SER B H    1 
ATOM   6885  H HA   . SER B 1 119 ? -13.584 55.494  37.854 1.00 11.53 ?  85   SER B HA   1 
ATOM   6886  H HB2  . SER B 1 119 ? -12.749 55.394  35.675 1.00 12.19 ?  85   SER B HB2  1 
ATOM   6887  H HB3  . SER B 1 119 ? -14.096 54.697  35.198 1.00 12.19 ?  85   SER B HB3  1 
ATOM   6888  H HG   . SER B 1 119 ? -15.105 56.529  35.397 1.00 14.47 ?  85   SER B HG   1 
ATOM   6889  N N    . ALA B 1 120 ? -16.054 53.617  37.057 1.00 8.92  ?  86   ALA B N    1 
ATOM   6890  C CA   . ALA B 1 120 ? -17.483 53.423  37.257 1.00 8.66  ?  86   ALA B CA   1 
ATOM   6891  C C    . ALA B 1 120 ? -17.816 53.191  38.727 1.00 10.65 ?  86   ALA B C    1 
ATOM   6892  O O    . ALA B 1 120 ? -18.825 53.698  39.232 1.00 10.09 ?  86   ALA B O    1 
ATOM   6893  C CB   . ALA B 1 120 ? -17.984 52.264  36.400 1.00 10.24 ?  86   ALA B CB   1 
ATOM   6894  H H    . ALA B 1 120 ? -15.667 52.980  36.628 1.00 10.71 ?  86   ALA B H    1 
ATOM   6895  H HA   . ALA B 1 120 ? -17.946 54.226  36.972 1.00 10.39 ?  86   ALA B HA   1 
ATOM   6896  H HB1  . ALA B 1 120 ? -18.939 52.158  36.539 1.00 12.29 ?  86   ALA B HB1  1 
ATOM   6897  H HB2  . ALA B 1 120 ? -17.805 52.460  35.467 1.00 12.29 ?  86   ALA B HB2  1 
ATOM   6898  H HB3  . ALA B 1 120 ? -17.520 51.454  36.663 1.00 12.29 ?  86   ALA B HB3  1 
ATOM   6899  N N    . ILE B 1 121 ? -17.001 52.396  39.431 1.00 9.22  ?  87   ILE B N    1 
ATOM   6900  C CA   . ILE B 1 121 ? -17.207 52.171  40.867 1.00 10.04 ?  87   ILE B CA   1 
ATOM   6901  C C    . ILE B 1 121 ? -17.164 53.497  41.608 1.00 10.33 ?  87   ILE B C    1 
ATOM   6902  O O    . ILE B 1 121 ? -18.044 53.806  42.426 1.00 9.93  ?  87   ILE B O    1 
ATOM   6903  C CB   . ILE B 1 121 ? -16.141 51.203  41.421 1.00 9.46  ?  87   ILE B CB   1 
ATOM   6904  C CG1  . ILE B 1 121 ? -16.349 49.786  40.895 1.00 8.67  ?  87   ILE B CG1  1 
ATOM   6905  C CG2  . ILE B 1 121 ? -16.148 51.185  42.961 1.00 8.76  ?  87   ILE B CG2  1 
ATOM   6906  C CD1  . ILE B 1 121 ? -15.158 48.854  41.224 1.00 10.64 ?  87   ILE B CD1  1 
ATOM   6907  H H    . ILE B 1 121 ? -16.326 51.977  39.103 1.00 11.06 ?  87   ILE B H    1 
ATOM   6908  H HA   . ILE B 1 121 ? -18.080 51.768  40.993 1.00 12.04 ?  87   ILE B HA   1 
ATOM   6909  H HB   . ILE B 1 121 ? -15.281 51.529  41.113 1.00 11.35 ?  87   ILE B HB   1 
ATOM   6910  H HG12 . ILE B 1 121 ? -17.147 49.411  41.301 1.00 10.40 ?  87   ILE B HG12 1 
ATOM   6911  H HG13 . ILE B 1 121 ? -16.451 49.817  39.931 1.00 10.40 ?  87   ILE B HG13 1 
ATOM   6912  H HG21 . ILE B 1 121 ? -15.507 50.527  43.272 1.00 10.51 ?  87   ILE B HG21 1 
ATOM   6913  H HG22 . ILE B 1 121 ? -15.903 52.065  43.288 1.00 10.51 ?  87   ILE B HG22 1 
ATOM   6914  H HG23 . ILE B 1 121 ? -17.037 50.954  43.270 1.00 10.51 ?  87   ILE B HG23 1 
ATOM   6915  H HD11 . ILE B 1 121 ? -15.241 48.040  40.704 1.00 12.77 ?  87   ILE B HD11 1 
ATOM   6916  H HD12 . ILE B 1 121 ? -14.331 49.308  40.999 1.00 12.77 ?  87   ILE B HD12 1 
ATOM   6917  H HD13 . ILE B 1 121 ? -15.173 48.645  42.171 1.00 12.77 ?  87   ILE B HD13 1 
ATOM   6918  N N    . LYS B 1 122 ? -16.121 54.297  41.348 1.00 9.90  ?  88   LYS B N    1 
ATOM   6919  C CA   . LYS B 1 122 ? -15.955 55.549  42.081 1.00 9.61  ?  88   LYS B CA   1 
ATOM   6920  C C    . LYS B 1 122 ? -17.076 56.532  41.785 1.00 11.14 ?  88   LYS B C    1 
ATOM   6921  O O    . LYS B 1 122 ? -17.403 57.347  42.648 1.00 11.95 ?  88   LYS B O    1 
ATOM   6922  C CB   . LYS B 1 122 ? -14.608 56.185  41.755 1.00 10.67 ?  88   LYS B CB   1 
ATOM   6923  C CG   . LYS B 1 122 ? -13.394 55.442  42.315 1.00 11.27 ?  88   LYS B CG   1 
ATOM   6924  C CD   . LYS B 1 122 ? -13.275 55.608  43.798 1.00 14.38 ?  88   LYS B CD   1 
ATOM   6925  C CE   . LYS B 1 122 ? -11.952 55.022  44.284 1.00 13.18 ?  88   LYS B CE   1 
ATOM   6926  N NZ   . LYS B 1 122 ? -11.677 55.474  45.634 1.00 14.53 ?  88   LYS B NZ   1 
ATOM   6927  H H    . LYS B 1 122 ? -15.510 54.138  40.764 1.00 11.88 ?  88   LYS B H    1 
ATOM   6928  H HA   . LYS B 1 122 ? -15.971 55.348  43.030 1.00 11.54 ?  88   LYS B HA   1 
ATOM   6929  H HB2  . LYS B 1 122 ? -14.510 56.218  40.790 1.00 12.80 ?  88   LYS B HB2  1 
ATOM   6930  H HB3  . LYS B 1 122 ? -14.595 57.083  42.121 1.00 12.80 ?  88   LYS B HB3  1 
ATOM   6931  H HG2  . LYS B 1 122 ? -13.481 54.495  42.122 1.00 13.52 ?  88   LYS B HG2  1 
ATOM   6932  H HG3  . LYS B 1 122 ? -12.588 55.792  41.905 1.00 13.52 ?  88   LYS B HG3  1 
ATOM   6933  H HD2  . LYS B 1 122 ? -13.300 56.551  44.024 1.00 17.26 ?  88   LYS B HD2  1 
ATOM   6934  H HD3  . LYS B 1 122 ? -14.003 55.142  44.239 1.00 17.26 ?  88   LYS B HD3  1 
ATOM   6935  H HE2  . LYS B 1 122 ? -12.004 54.053  44.284 1.00 15.81 ?  88   LYS B HE2  1 
ATOM   6936  H HE3  . LYS B 1 122 ? -11.232 55.315  43.704 1.00 15.81 ?  88   LYS B HE3  1 
ATOM   6937  H HZ1  . LYS B 1 122 ? -11.494 56.345  45.632 1.00 17.44 ?  88   LYS B HZ1  1 
ATOM   6938  H HZ2  . LYS B 1 122 ? -12.384 55.328  46.154 1.00 17.44 ?  88   LYS B HZ2  1 
ATOM   6939  H HZ3  . LYS B 1 122 ? -10.978 55.033  45.966 1.00 17.44 ?  88   LYS B HZ3  1 
ATOM   6940  N N    . LEU B 1 123 ? -17.653 56.483  40.586 1.00 10.37 ?  89   LEU B N    1 
ATOM   6941  C CA   . LEU B 1 123 ? -18.782 57.360  40.288 1.00 12.18 ?  89   LEU B CA   1 
ATOM   6942  C C    . LEU B 1 123 ? -19.987 57.015  41.145 1.00 13.62 ?  89   LEU B C    1 
ATOM   6943  O O    . LEU B 1 123 ? -20.746 57.914  41.538 1.00 13.62 ?  89   LEU B O    1 
ATOM   6944  C CB   . LEU B 1 123 ? -19.111 57.289  38.801 1.00 11.40 ?  89   LEU B CB   1 
ATOM   6945  C CG   . LEU B 1 123 ? -20.235 58.188  38.274 1.00 11.96 ?  89   LEU B CG   1 
ATOM   6946  C CD1  . LEU B 1 123 ? -19.874 59.639  38.498 1.00 12.71 ?  89   LEU B CD1  1 
ATOM   6947  C CD2  . LEU B 1 123 ? -20.455 57.935  36.800 1.00 13.74 ?  89   LEU B CD2  1 
ATOM   6948  H H    . LEU B 1 123 ? -17.417 55.964  39.943 1.00 12.44 ?  89   LEU B H    1 
ATOM   6949  H HA   . LEU B 1 123 ? -18.543 58.279  40.485 1.00 14.61 ?  89   LEU B HA   1 
ATOM   6950  H HB2  . LEU B 1 123 ? -18.310 57.528  38.309 1.00 13.68 ?  89   LEU B HB2  1 
ATOM   6951  H HB3  . LEU B 1 123 ? -19.365 56.376  38.597 1.00 13.68 ?  89   LEU B HB3  1 
ATOM   6952  H HG   . LEU B 1 123 ? -21.059 57.990  38.746 1.00 14.35 ?  89   LEU B HG   1 
ATOM   6953  H HD11 . LEU B 1 123 ? -20.551 60.200  38.088 1.00 15.25 ?  89   LEU B HD11 1 
ATOM   6954  H HD12 . LEU B 1 123 ? -19.835 59.810  39.452 1.00 15.25 ?  89   LEU B HD12 1 
ATOM   6955  H HD13 . LEU B 1 123 ? -19.010 59.815  38.094 1.00 15.25 ?  89   LEU B HD13 1 
ATOM   6956  H HD21 . LEU B 1 123 ? -21.129 58.550  36.471 1.00 16.49 ?  89   LEU B HD21 1 
ATOM   6957  H HD22 . LEU B 1 123 ? -19.620 58.076  36.327 1.00 16.49 ?  89   LEU B HD22 1 
ATOM   6958  H HD23 . LEU B 1 123 ? -20.754 57.020  36.678 1.00 16.49 ?  89   LEU B HD23 1 
ATOM   6959  N N    . LYS B 1 124 ? -20.175 55.733  41.465 1.00 11.08 ?  90   LYS B N    1 
ATOM   6960  C CA   . LYS B 1 124 ? -21.286 55.309  42.306 1.00 10.83 ?  90   LYS B CA   1 
ATOM   6961  C C    . LYS B 1 124 ? -20.981 55.522  43.786 1.00 13.13 ?  90   LYS B C    1 
ATOM   6962  O O    . LYS B 1 124 ? -21.875 55.897  44.560 1.00 15.98 ?  90   LYS B O    1 
ATOM   6963  C CB   . LYS B 1 124 ? -21.579 53.834  42.032 1.00 13.16 ?  90   LYS B CB   1 
ATOM   6964  C CG   . LYS B 1 124 ? -22.495 53.595  40.869 1.00 28.11 ?  90   LYS B CG   1 
ATOM   6965  C CD   . LYS B 1 124 ? -23.847 54.241  41.135 1.00 36.23 ?  90   LYS B CD   1 
ATOM   6966  C CE   . LYS B 1 124 ? -24.263 54.023  42.585 1.00 29.20 ?  90   LYS B CE   1 
ATOM   6967  H H    . LYS B 1 124 ? -19.669 55.088  41.205 1.00 13.29 ?  90   LYS B H    1 
ATOM   6968  H HA   . LYS B 1 124 ? -22.074 55.831  42.089 1.00 13.00 ?  90   LYS B HA   1 
ATOM   6969  N N    . ASN B 1 125 ? -19.734 55.296  44.216 1.00 10.90 ?  91   ASN B N    1 
ATOM   6970  C CA   . ASN B 1 125 ? -19.360 55.500  45.612 1.00 10.57 ?  91   ASN B CA   1 
ATOM   6971  C C    . ASN B 1 125 ? -17.891 55.906  45.652 1.00 11.39 ?  91   ASN B C    1 
ATOM   6972  O O    . ASN B 1 125 ? -17.007 55.051  45.571 1.00 11.46 ?  91   ASN B O    1 
ATOM   6973  C CB   . ASN B 1 125 ? -19.587 54.249  46.445 1.00 11.74 ?  91   ASN B CB   1 
ATOM   6974  C CG   . ASN B 1 125 ? -19.406 54.518  47.925 1.00 14.37 ?  91   ASN B CG   1 
ATOM   6975  O OD1  . ASN B 1 125 ? -18.803 55.513  48.325 1.00 13.89 ?  91   ASN B OD1  1 
ATOM   6976  N ND2  . ASN B 1 125 ? -19.967 53.640  48.754 1.00 24.44 ?  91   ASN B ND2  1 
ATOM   6977  H H    . ASN B 1 125 ? -19.090 55.023  43.716 1.00 13.08 ?  91   ASN B H    1 
ATOM   6978  H HA   . ASN B 1 125 ? -19.902 56.221  45.969 1.00 12.68 ?  91   ASN B HA   1 
ATOM   6979  H HB2  . ASN B 1 125 ? -20.491 53.929  46.302 1.00 14.09 ?  91   ASN B HB2  1 
ATOM   6980  H HB3  . ASN B 1 125 ? -18.948 53.568  46.180 1.00 14.09 ?  91   ASN B HB3  1 
ATOM   6981  H HD21 . ASN B 1 125 ? -20.400 52.967  48.439 1.00 29.33 ?  91   ASN B HD21 1 
ATOM   6982  H HD22 . ASN B 1 125 ? -19.895 53.745  49.604 1.00 29.33 ?  91   ASN B HD22 1 
ATOM   6983  N N    . ASN B 1 126 ? -17.615 57.196  45.826 1.00 11.14 ?  92   ASN B N    1 
ATOM   6984  C CA   . ASN B 1 126 ? -16.225 57.610  45.745 1.00 13.22 ?  92   ASN B CA   1 
ATOM   6985  C C    . ASN B 1 126 ? -15.428 57.232  46.985 1.00 12.48 ?  92   ASN B C    1 
ATOM   6986  O O    . ASN B 1 126 ? -14.193 57.303  46.953 1.00 15.19 ?  92   ASN B O    1 
ATOM   6987  C CB   . ASN B 1 126 ? -16.069 59.099  45.399 1.00 19.00 ?  92   ASN B CB   1 
ATOM   6988  C CG   . ASN B 1 126 ? -16.721 60.006  46.395 1.00 20.41 ?  92   ASN B CG   1 
ATOM   6989  O OD1  . ASN B 1 126 ? -16.317 60.064  47.551 1.00 29.61 ?  92   ASN B OD1  1 
ATOM   6990  N ND2  . ASN B 1 126 ? -17.688 60.804  45.929 1.00 25.25 ?  92   ASN B ND2  1 
ATOM   6991  H H    . ASN B 1 126 ? -18.189 57.817  45.984 1.00 13.37 ?  92   ASN B H    1 
ATOM   6992  H HA   . ASN B 1 126 ? -15.822 57.152  44.992 1.00 15.86 ?  92   ASN B HA   1 
ATOM   6993  H HB2  . ASN B 1 126 ? -15.125 59.318  45.369 1.00 22.80 ?  92   ASN B HB2  1 
ATOM   6994  H HB3  . ASN B 1 126 ? -16.476 59.265  44.534 1.00 22.80 ?  92   ASN B HB3  1 
ATOM   6995  H HD21 . ASN B 1 126 ? -17.903 60.778  45.096 1.00 30.30 ?  92   ASN B HD21 1 
ATOM   6996  H HD22 . ASN B 1 126 ? -18.094 61.344  46.461 1.00 30.30 ?  92   ASN B HD22 1 
ATOM   6997  N N    . LYS B 1 127 ? -16.090 56.751  48.034 1.00 10.66 ?  93   LYS B N    1 
ATOM   6998  C CA   . LYS B 1 127 ? -15.415 56.318  49.246 1.00 11.78 ?  93   LYS B CA   1 
ATOM   6999  C C    . LYS B 1 127 ? -14.944 54.865  49.194 1.00 11.77 ?  93   LYS B C    1 
ATOM   7000  O O    . LYS B 1 127 ? -14.130 54.479  50.036 1.00 12.74 ?  93   LYS B O    1 
ATOM   7001  C CB   . LYS B 1 127 ? -16.330 56.501  50.460 1.00 14.43 ?  93   LYS B CB   1 
ATOM   7002  C CG   . LYS B 1 127 ? -16.733 57.958  50.766 1.00 17.87 ?  93   LYS B CG   1 
ATOM   7003  C CD   . LYS B 1 127 ? -17.366 58.059  52.145 1.00 28.85 ?  93   LYS B CD   1 
ATOM   7004  H H    . LYS B 1 127 ? -16.946 56.665  48.065 1.00 12.79 ?  93   LYS B H    1 
ATOM   7005  H HA   . LYS B 1 127 ? -14.633 56.879  49.369 1.00 14.14 ?  93   LYS B HA   1 
ATOM   7006  H HB2  . LYS B 1 127 ? -17.146 56.001  50.307 1.00 17.32 ?  93   LYS B HB2  1 
ATOM   7007  H HB3  . LYS B 1 127 ? -15.872 56.157  51.243 1.00 17.32 ?  93   LYS B HB3  1 
ATOM   7008  H HG2  . LYS B 1 127 ? -15.946 58.524  50.745 1.00 21.44 ?  93   LYS B HG2  1 
ATOM   7009  H HG3  . LYS B 1 127 ? -17.378 58.261  50.107 1.00 21.44 ?  93   LYS B HG3  1 
ATOM   7010  H HD3  . LYS B 1 127 ? -16.734 57.736  52.807 1.00 34.62 ?  93   LYS B HD3  1 
ATOM   7011  N N    . ALA B 1 128 ? -15.423 54.068  48.236 1.00 10.61 ?  94   ALA B N    1 
ATOM   7012  C CA   . ALA B 1 128 ? -14.932 52.702  48.073 1.00 10.23 ?  94   ALA B CA   1 
ATOM   7013  C C    . ALA B 1 128 ? -13.448 52.742  47.723 1.00 10.47 ?  94   ALA B C    1 
ATOM   7014  O O    . ALA B 1 128 ? -13.014 53.548  46.898 1.00 13.13 ?  94   ALA B O    1 
ATOM   7015  C CB   . ALA B 1 128 ? -15.694 52.007  46.944 1.00 12.29 ?  94   ALA B CB   1 
ATOM   7016  H H    . ALA B 1 128 ? -16.031 54.294  47.671 1.00 12.73 ?  94   ALA B H    1 
ATOM   7017  H HA   . ALA B 1 128 ? -15.063 52.200  48.893 1.00 12.28 ?  94   ALA B HA   1 
ATOM   7018  H HB1  . ALA B 1 128 ? -15.399 51.084  46.885 1.00 14.75 ?  94   ALA B HB1  1 
ATOM   7019  H HB2  . ALA B 1 128 ? -16.644 52.038  47.138 1.00 14.75 ?  94   ALA B HB2  1 
ATOM   7020  H HB3  . ALA B 1 128 ? -15.511 52.466  46.110 1.00 14.75 ?  94   ALA B HB3  1 
ATOM   7021  N N    . LYS B 1 129 ? -12.647 51.875  48.343 1.00 8.81  ?  95   LYS B N    1 
ATOM   7022  C CA   . LYS B 1 129 ? -11.232 51.773  48.001 1.00 9.25  ?  95   LYS B CA   1 
ATOM   7023  C C    . LYS B 1 129 ? -11.027 50.641  47.009 1.00 7.95  ?  95   LYS B C    1 
ATOM   7024  O O    . LYS B 1 129 ? -11.512 49.530  47.227 1.00 9.41  ?  95   LYS B O    1 
ATOM   7025  C CB   . LYS B 1 129 ? -10.365 51.534  49.242 1.00 9.77  ?  95   LYS B CB   1 
ATOM   7026  C CG   . LYS B 1 129 ? -10.358 52.709  50.219 1.00 9.61  ?  95   LYS B CG   1 
ATOM   7027  C CD   . LYS B 1 129 ? -9.770  53.981  49.626 1.00 10.85 ?  95   LYS B CD   1 
ATOM   7028  C CE   . LYS B 1 129 ? -9.655  55.014  50.736 1.00 13.54 ?  95   LYS B CE   1 
ATOM   7029  N NZ   . LYS B 1 129 ? -8.926  56.211  50.248 1.00 18.68 ?  95   LYS B NZ   1 
ATOM   7030  H H    . LYS B 1 129 ? -12.902 51.336  48.963 1.00 10.58 ?  95   LYS B H    1 
ATOM   7031  H HA   . LYS B 1 129 ? -10.950 52.607  47.593 1.00 11.10 ?  95   LYS B HA   1 
ATOM   7032  H HB2  . LYS B 1 129 ? -10.703 50.757  49.714 1.00 11.72 ?  95   LYS B HB2  1 
ATOM   7033  H HB3  . LYS B 1 129 ? -9.450  51.378  48.958 1.00 11.72 ?  95   LYS B HB3  1 
ATOM   7034  H HG2  . LYS B 1 129 ? -11.270 52.901  50.487 1.00 11.53 ?  95   LYS B HG2  1 
ATOM   7035  H HG3  . LYS B 1 129 ? -9.827  52.470  50.995 1.00 11.53 ?  95   LYS B HG3  1 
ATOM   7036  H HD2  . LYS B 1 129 ? -8.888  53.803  49.263 1.00 13.02 ?  95   LYS B HD2  1 
ATOM   7037  H HD3  . LYS B 1 129 ? -10.352 54.324  48.930 1.00 13.02 ?  95   LYS B HD3  1 
ATOM   7038  H HE2  . LYS B 1 129 ? -10.541 55.285  51.023 1.00 16.25 ?  95   LYS B HE2  1 
ATOM   7039  H HE3  . LYS B 1 129 ? -9.166  54.636  51.484 1.00 16.25 ?  95   LYS B HE3  1 
ATOM   7040  H HZ1  . LYS B 1 129 ? -8.084  55.997  50.056 1.00 22.41 ?  95   LYS B HZ1  1 
ATOM   7041  H HZ2  . LYS B 1 129 ? -9.318  56.527  49.514 1.00 22.41 ?  95   LYS B HZ2  1 
ATOM   7042  H HZ3  . LYS B 1 129 ? -8.928  56.844  50.873 1.00 22.41 ?  95   LYS B HZ3  1 
ATOM   7043  N N    . VAL B 1 130 ? -10.292 50.922  45.942 1.00 8.31  ?  96   VAL B N    1 
ATOM   7044  C CA   . VAL B 1 130 ? -10.095 49.978  44.842 1.00 7.11  ?  96   VAL B CA   1 
ATOM   7045  C C    . VAL B 1 130 ? -8.603  49.696  44.702 1.00 7.90  ?  96   VAL B C    1 
ATOM   7046  O O    . VAL B 1 130 ? -7.800  50.630  44.531 1.00 8.81  ?  96   VAL B O    1 
ATOM   7047  C CB   . VAL B 1 130 ? -10.672 50.522  43.522 1.00 9.16  ?  96   VAL B CB   1 
ATOM   7048  C CG1  . VAL B 1 130 ? -10.434 49.543  42.371 1.00 10.55 ?  96   VAL B CG1  1 
ATOM   7049  C CG2  . VAL B 1 130 ? -12.171 50.818  43.669 1.00 11.92 ?  96   VAL B CG2  1 
ATOM   7050  H H    . VAL B 1 130 ? -9.886  51.671  45.826 1.00 9.97  ?  96   VAL B H    1 
ATOM   7051  H HA   . VAL B 1 130 ? -10.536 49.142  45.060 1.00 8.54  ?  96   VAL B HA   1 
ATOM   7052  H HB   . VAL B 1 130 ? -10.215 51.351  43.309 1.00 11.00 ?  96   VAL B HB   1 
ATOM   7053  H HG11 . VAL B 1 130 ? -10.752 49.942  41.546 1.00 12.66 ?  96   VAL B HG11 1 
ATOM   7054  H HG12 . VAL B 1 130 ? -9.484  49.359  42.305 1.00 12.66 ?  96   VAL B HG12 1 
ATOM   7055  H HG13 . VAL B 1 130 ? -10.918 48.722  42.550 1.00 12.66 ?  96   VAL B HG13 1 
ATOM   7056  H HG21 . VAL B 1 130 ? -12.503 51.186  42.835 1.00 14.31 ?  96   VAL B HG21 1 
ATOM   7057  H HG22 . VAL B 1 130 ? -12.637 49.993  43.876 1.00 14.31 ?  96   VAL B HG22 1 
ATOM   7058  H HG23 . VAL B 1 130 ? -12.297 51.459  44.386 1.00 14.31 ?  96   VAL B HG23 1 
ATOM   7059  N N    . LEU B 1 131 ? -8.231  48.406  44.778 1.00 7.91  ?  97   LEU B N    1 
ATOM   7060  C CA   . LEU B 1 131 ? -6.848  47.962  44.643 1.00 7.87  ?  97   LEU B CA   1 
ATOM   7061  C C    . LEU B 1 131 ? -6.625  47.271  43.301 1.00 8.13  ?  97   LEU B C    1 
ATOM   7062  O O    . LEU B 1 131 ? -7.483  46.523  42.816 1.00 8.31  ?  97   LEU B O    1 
ATOM   7063  C CB   . LEU B 1 131 ? -6.448  46.993  45.767 1.00 7.80  ?  97   LEU B CB   1 
ATOM   7064  C CG   . LEU B 1 131 ? -6.707  47.473  47.186 1.00 7.74  ?  97   LEU B CG   1 
ATOM   7065  C CD1  . LEU B 1 131 ? -6.264  46.419  48.192 1.00 9.33  ?  97   LEU B CD1  1 
ATOM   7066  C CD2  . LEU B 1 131 ? -6.016  48.810  47.474 1.00 10.28 ?  97   LEU B CD2  1 
ATOM   7067  H H    . LEU B 1 131 ? -8.782  47.759  44.911 1.00 9.50  ?  97   LEU B H    1 
ATOM   7068  H HA   . LEU B 1 131 ? -6.280  48.746  44.686 1.00 9.44  ?  97   LEU B HA   1 
ATOM   7069  H HB2  . LEU B 1 131 ? -6.946  46.169  45.648 1.00 9.36  ?  97   LEU B HB2  1 
ATOM   7070  H HB3  . LEU B 1 131 ? -5.496  46.819  45.692 1.00 9.36  ?  97   LEU B HB3  1 
ATOM   7071  H HG   . LEU B 1 131 ? -7.661  47.619  47.285 1.00 9.29  ?  97   LEU B HG   1 
ATOM   7072  H HD11 . LEU B 1 131 ? -6.310  46.794  49.085 1.00 11.20 ?  97   LEU B HD11 1 
ATOM   7073  H HD12 . LEU B 1 131 ? -6.853  45.651  48.125 1.00 11.20 ?  97   LEU B HD12 1 
ATOM   7074  H HD13 . LEU B 1 131 ? -5.352  46.154  47.991 1.00 11.20 ?  97   LEU B HD13 1 
ATOM   7075  H HD21 . LEU B 1 131 ? -6.133  49.031  48.411 1.00 12.33 ?  97   LEU B HD21 1 
ATOM   7076  H HD22 . LEU B 1 131 ? -5.071  48.727  47.269 1.00 12.33 ?  97   LEU B HD22 1 
ATOM   7077  H HD23 . LEU B 1 131 ? -6.415  49.498  46.919 1.00 12.33 ?  97   LEU B HD23 1 
ATOM   7078  N N    . TYR B 1 132 ? -5.437  47.488  42.727 1.00 7.05  ?  98   TYR B N    1 
ATOM   7079  C CA   . TYR B 1 132 ? -4.996  46.839  41.500 1.00 8.26  ?  98   TYR B CA   1 
ATOM   7080  C C    . TYR B 1 132 ? -4.132  45.630  41.838 1.00 7.30  ?  98   TYR B C    1 
ATOM   7081  O O    . TYR B 1 132 ? -3.068  45.763  42.459 1.00 7.52  ?  98   TYR B O    1 
ATOM   7082  C CB   . TYR B 1 132 ? -4.138  47.826  40.714 1.00 8.23  ?  98   TYR B CB   1 
ATOM   7083  C CG   . TYR B 1 132 ? -3.644  47.356  39.370 1.00 7.59  ?  98   TYR B CG   1 
ATOM   7084  C CD1  . TYR B 1 132 ? -4.533  46.876  38.427 1.00 7.91  ?  98   TYR B CD1  1 
ATOM   7085  C CD2  . TYR B 1 132 ? -2.300  47.458  39.024 1.00 8.03  ?  98   TYR B CD2  1 
ATOM   7086  C CE1  . TYR B 1 132 ? -4.108  46.504  37.172 1.00 7.40  ?  98   TYR B CE1  1 
ATOM   7087  C CE2  . TYR B 1 132 ? -1.858  47.078  37.767 1.00 8.90  ?  98   TYR B CE2  1 
ATOM   7088  C CZ   . TYR B 1 132 ? -2.779  46.618  36.839 1.00 8.89  ?  98   TYR B CZ   1 
ATOM   7089  O OH   . TYR B 1 132 ? -2.390  46.266  35.575 1.00 10.35 ?  98   TYR B OH   1 
ATOM   7090  H H    . TYR B 1 132 ? -4.850  48.029  43.046 1.00 8.46  ?  98   TYR B H    1 
ATOM   7091  H HA   . TYR B 1 132 ? -5.766  46.544  40.990 1.00 9.91  ?  98   TYR B HA   1 
ATOM   7092  H HB2  . TYR B 1 132 ? -4.663  48.627  40.561 1.00 9.88  ?  98   TYR B HB2  1 
ATOM   7093  H HB3  . TYR B 1 132 ? -3.356  48.038  41.247 1.00 9.88  ?  98   TYR B HB3  1 
ATOM   7094  H HD1  . TYR B 1 132 ? -5.434  46.803  38.645 1.00 9.49  ?  98   TYR B HD1  1 
ATOM   7095  H HD2  . TYR B 1 132 ? -1.691  47.785  39.645 1.00 9.64  ?  98   TYR B HD2  1 
ATOM   7096  H HE1  . TYR B 1 132 ? -4.718  46.177  36.551 1.00 8.88  ?  98   TYR B HE1  1 
ATOM   7097  H HE2  . TYR B 1 132 ? -0.955  47.131  37.549 1.00 10.68 ?  98   TYR B HE2  1 
ATOM   7098  H HH   . TYR B 1 132 ? -1.690  46.680  35.364 1.00 12.42 ?  98   TYR B HH   1 
ATOM   7099  N N    . TYR B 1 133 ? -4.575  44.463  41.394 1.00 7.60  ?  99   TYR B N    1 
ATOM   7100  C CA   . TYR B 1 133 ? -3.777  43.254  41.565 1.00 6.30  ?  99   TYR B CA   1 
ATOM   7101  C C    . TYR B 1 133 ? -2.486  43.349  40.770 1.00 6.94  ?  99   TYR B C    1 
ATOM   7102  O O    . TYR B 1 133 ? -2.469  43.768  39.616 1.00 6.81  ?  99   TYR B O    1 
ATOM   7103  C CB   . TYR B 1 133 ? -4.598  42.062  41.094 1.00 7.90  ?  99   TYR B CB   1 
ATOM   7104  C CG   . TYR B 1 133 ? -3.885  40.725  41.074 1.00 7.19  ?  99   TYR B CG   1 
ATOM   7105  C CD1  . TYR B 1 133 ? -3.141  40.329  39.963 1.00 6.19  ?  99   TYR B CD1  1 
ATOM   7106  C CD2  . TYR B 1 133 ? -3.981  39.849  42.150 1.00 8.00  ?  99   TYR B CD2  1 
ATOM   7107  C CE1  . TYR B 1 133 ? -2.494  39.089  39.948 1.00 7.01  ?  99   TYR B CE1  1 
ATOM   7108  C CE2  . TYR B 1 133 ? -3.371  38.607  42.126 1.00 7.47  ?  99   TYR B CE2  1 
ATOM   7109  C CZ   . TYR B 1 133 ? -2.608  38.264  41.033 1.00 6.64  ?  99   TYR B CZ   1 
ATOM   7110  O OH   . TYR B 1 133 ? -1.992  37.023  40.981 1.00 7.19  ?  99   TYR B OH   1 
ATOM   7111  H H    . TYR B 1 133 ? -5.327  44.342  40.994 1.00 9.11  ?  99   TYR B H    1 
ATOM   7112  H HA   . TYR B 1 133 ? -3.540  43.133  42.498 1.00 7.56  ?  99   TYR B HA   1 
ATOM   7113  H HB2  . TYR B 1 133 ? -5.362  41.969  41.683 1.00 9.48  ?  99   TYR B HB2  1 
ATOM   7114  H HB3  . TYR B 1 133 ? -4.896  42.239  40.188 1.00 9.48  ?  99   TYR B HB3  1 
ATOM   7115  H HD1  . TYR B 1 133 ? -3.075  40.893  39.227 1.00 7.43  ?  99   TYR B HD1  1 
ATOM   7116  H HD2  . TYR B 1 133 ? -4.466  40.103  42.902 1.00 9.60  ?  99   TYR B HD2  1 
ATOM   7117  H HE1  . TYR B 1 133 ? -1.992  38.828  39.209 1.00 8.41  ?  99   TYR B HE1  1 
ATOM   7118  H HE2  . TYR B 1 133 ? -3.474  38.015  42.835 1.00 8.97  ?  99   TYR B HE2  1 
ATOM   7119  H HH   . TYR B 1 133 ? -2.029  36.652  41.734 1.00 8.62  ?  99   TYR B HH   1 
ATOM   7120  N N    . ARG B 1 134 ? -1.395  42.904  41.376 1.00 6.74  ?  100  ARG B N    1 
ATOM   7121  C CA   . ARG B 1 134 ? -0.150  42.754  40.631 1.00 6.76  ?  100  ARG B CA   1 
ATOM   7122  C C    . ARG B 1 134 ? 0.626   41.578  41.189 1.00 7.16  ?  100  ARG B C    1 
ATOM   7123  O O    . ARG B 1 134 ? 0.952   41.542  42.376 1.00 7.56  ?  100  ARG B O    1 
ATOM   7124  C CB   . ARG B 1 134 ? 0.724   44.011  40.661 1.00 7.33  ?  100  ARG B CB   1 
ATOM   7125  C CG   . ARG B 1 134 ? 1.744   44.053  39.522 1.00 7.41  ?  100  ARG B CG   1 
ATOM   7126  C CD   . ARG B 1 134 ? 1.127   44.442  38.195 1.00 9.61  ?  100  ARG B CD   1 
ATOM   7127  N NE   . ARG B 1 134 ? 2.133   44.742  37.179 1.00 9.51  ?  100  ARG B NE   1 
ATOM   7128  C CZ   . ARG B 1 134 ? 2.263   44.110  36.018 1.00 8.63  ?  100  ARG B CZ   1 
ATOM   7129  N NH1  . ARG B 1 134 ? 1.528   43.060  35.708 1.00 9.98  ?  100  ARG B NH1  1 
ATOM   7130  N NH2  . ARG B 1 134 ? 3.161   44.538  35.136 1.00 9.89  ?  100  ARG B NH2  1 
ATOM   7131  H H    . ARG B 1 134 ? -1.348  42.685  42.206 1.00 8.09  ?  100  ARG B H    1 
ATOM   7132  H HA   . ARG B 1 134 ? -0.386  42.576  39.707 1.00 8.11  ?  100  ARG B HA   1 
ATOM   7133  H HB2  . ARG B 1 134 ? 0.154   44.793  40.583 1.00 8.79  ?  100  ARG B HB2  1 
ATOM   7134  H HB3  . ARG B 1 134 ? 1.210   44.038  41.500 1.00 8.79  ?  100  ARG B HB3  1 
ATOM   7135  H HG2  . ARG B 1 134 ? 2.430   44.704  39.735 1.00 8.90  ?  100  ARG B HG2  1 
ATOM   7136  H HG3  . ARG B 1 134 ? 2.141   43.173  39.421 1.00 8.90  ?  100  ARG B HG3  1 
ATOM   7137  H HD2  . ARG B 1 134 ? 0.581   43.709  37.871 1.00 11.53 ?  100  ARG B HD2  1 
ATOM   7138  H HD3  . ARG B 1 134 ? 0.579   45.233  38.319 1.00 11.53 ?  100  ARG B HD3  1 
ATOM   7139  H HE   . ARG B 1 134 ? 2.687   45.378  37.347 1.00 11.42 ?  100  ARG B HE   1 
ATOM   7140  H HH11 . ARG B 1 134 ? 0.944   42.765  36.265 1.00 11.98 ?  100  ARG B HH11 1 
ATOM   7141  H HH12 . ARG B 1 134 ? 1.633   42.671  34.948 1.00 11.98 ?  100  ARG B HH12 1 
ATOM   7142  H HH21 . ARG B 1 134 ? 3.653   45.219  35.319 1.00 11.87 ?  100  ARG B HH21 1 
ATOM   7143  H HH22 . ARG B 1 134 ? 3.249   44.134  34.382 1.00 11.87 ?  100  ARG B HH22 1 
ATOM   7144  N N    . ASN B 1 135 ? 0.954   40.640  40.319 1.00 7.04  ?  101  ASN B N    1 
ATOM   7145  C CA   . ASN B 1 135 ? 1.773   39.504  40.710 1.00 6.10  ?  101  ASN B CA   1 
ATOM   7146  C C    . ASN B 1 135 ? 3.243   39.885  40.570 1.00 7.63  ?  101  ASN B C    1 
ATOM   7147  O O    . ASN B 1 135 ? 3.664   40.363  39.510 1.00 7.80  ?  101  ASN B O    1 
ATOM   7148  C CB   . ASN B 1 135 ? 1.421   38.303  39.844 1.00 7.19  ?  101  ASN B CB   1 
ATOM   7149  C CG   . ASN B 1 135 ? 1.823   37.016  40.491 1.00 6.58  ?  101  ASN B CG   1 
ATOM   7150  O OD1  . ASN B 1 135 ? 3.023   36.752  40.667 1.00 7.24  ?  101  ASN B OD1  1 
ATOM   7151  N ND2  . ASN B 1 135 ? 0.845   36.218  40.893 1.00 7.70  ?  101  ASN B ND2  1 
ATOM   7152  H H    . ASN B 1 135 ? 0.714   40.637  39.493 1.00 8.45  ?  101  ASN B H    1 
ATOM   7153  H HA   . ASN B 1 135 ? 1.618   39.261  41.636 1.00 7.32  ?  101  ASN B HA   1 
ATOM   7154  H HB2  . ASN B 1 135 ? 0.463   38.283  39.699 1.00 8.62  ?  101  ASN B HB2  1 
ATOM   7155  H HB3  . ASN B 1 135 ? 1.885   38.374  38.995 1.00 8.62  ?  101  ASN B HB3  1 
ATOM   7156  H HD21 . ASN B 1 135 ? 1.029   35.467  41.270 1.00 9.24  ?  101  ASN B HD21 1 
ATOM   7157  H HD22 . ASN B 1 135 ? 0.025   36.451  40.777 1.00 9.24  ?  101  ASN B HD22 1 
ATOM   7158  N N    . VAL B 1 136 ? 4.019   39.667  41.642 1.00 7.67  ?  102  VAL B N    1 
ATOM   7159  C CA   . VAL B 1 136 ? 5.422   40.080  41.667 1.00 7.53  ?  102  VAL B CA   1 
ATOM   7160  C C    . VAL B 1 136 ? 6.327   39.195  40.811 1.00 8.18  ?  102  VAL B C    1 
ATOM   7161  O O    . VAL B 1 136 ? 7.400   39.654  40.396 1.00 9.37  ?  102  VAL B O    1 
ATOM   7162  C CB   . VAL B 1 136 ? 5.929   40.200  43.122 1.00 7.95  ?  102  VAL B CB   1 
ATOM   7163  C CG1  . VAL B 1 136 ? 6.169   38.832  43.749 1.00 8.78  ?  102  VAL B CG1  1 
ATOM   7164  C CG2  . VAL B 1 136 ? 7.192   41.068  43.196 1.00 9.86  ?  102  VAL B CG2  1 
ATOM   7165  H H    . VAL B 1 136 ? 3.755   39.282  42.364 1.00 9.21  ?  102  VAL B H    1 
ATOM   7166  H HA   . VAL B 1 136 ? 5.473   40.964  41.270 1.00 9.04  ?  102  VAL B HA   1 
ATOM   7167  H HB   . VAL B 1 136 ? 5.235   40.637  43.641 1.00 9.54  ?  102  VAL B HB   1 
ATOM   7168  H HG11 . VAL B 1 136 ? 6.277   38.939  44.707 1.00 10.54 ?  102  VAL B HG11 1 
ATOM   7169  H HG12 . VAL B 1 136 ? 5.408   38.261  43.563 1.00 10.54 ?  102  VAL B HG12 1 
ATOM   7170  H HG13 . VAL B 1 136 ? 6.973   38.446  43.367 1.00 10.54 ?  102  VAL B HG13 1 
ATOM   7171  H HG21 . VAL B 1 136 ? 7.428   41.203  44.127 1.00 11.83 ?  102  VAL B HG21 1 
ATOM   7172  H HG22 . VAL B 1 136 ? 7.914   40.614  42.734 1.00 11.83 ?  102  VAL B HG22 1 
ATOM   7173  H HG23 . VAL B 1 136 ? 7.014   41.922  42.773 1.00 11.83 ?  102  VAL B HG23 1 
ATOM   7174  N N    . VAL B 1 137 ? 5.924   37.964  40.489 1.00 8.68  ?  103  VAL B N    1 
ATOM   7175  C CA   . VAL B 1 137 ? 6.793   37.074  39.717 1.00 8.02  ?  103  VAL B CA   1 
ATOM   7176  C C    . VAL B 1 137 ? 6.111   36.341  38.577 1.00 8.51  ?  103  VAL B C    1 
ATOM   7177  O O    . VAL B 1 137 ? 6.821   35.901  37.657 1.00 9.91  ?  103  VAL B O    1 
ATOM   7178  C CB   . VAL B 1 137 ? 7.569   36.055  40.587 1.00 9.48  ?  103  VAL B CB   1 
ATOM   7179  C CG1  . VAL B 1 137 ? 8.739   36.688  41.280 1.00 11.16 ?  103  VAL B CG1  1 
ATOM   7180  C CG2  . VAL B 1 137 ? 6.662   35.334  41.566 1.00 9.04  ?  103  VAL B CG2  1 
ATOM   7181  H H    . VAL B 1 137 ? 5.163   37.625  40.702 1.00 10.41 ?  103  VAL B H    1 
ATOM   7182  H HA   . VAL B 1 137 ? 7.456   37.664  39.327 1.00 9.62  ?  103  VAL B HA   1 
ATOM   7183  H HB   . VAL B 1 137 ? 7.926   35.381  39.987 1.00 11.37 ?  103  VAL B HB   1 
ATOM   7184  H HG11 . VAL B 1 137 ? 9.236   36.002  41.751 1.00 13.39 ?  103  VAL B HG11 1 
ATOM   7185  H HG12 . VAL B 1 137 ? 9.307   37.112  40.618 1.00 13.39 ?  103  VAL B HG12 1 
ATOM   7186  H HG13 . VAL B 1 137 ? 8.413   37.351  41.909 1.00 13.39 ?  103  VAL B HG13 1 
ATOM   7187  H HG21 . VAL B 1 137 ? 7.185   34.684  42.061 1.00 10.85 ?  103  VAL B HG21 1 
ATOM   7188  H HG22 . VAL B 1 137 ? 6.276   35.982  42.175 1.00 10.85 ?  103  VAL B HG22 1 
ATOM   7189  H HG23 . VAL B 1 137 ? 5.958   34.884  41.072 1.00 10.85 ?  103  VAL B HG23 1 
ATOM   7190  N N    . ILE B 1 138 ? 4.806   36.110  38.573 1.00 8.49  ?  104  ILE B N    1 
ATOM   7191  C CA   . ILE B 1 138 ? 4.181   35.287  37.541 1.00 7.70  ?  104  ILE B CA   1 
ATOM   7192  C C    . ILE B 1 138 ? 3.677   36.180  36.421 1.00 8.39  ?  104  ILE B C    1 
ATOM   7193  O O    . ILE B 1 138 ? 2.923   37.128  36.666 1.00 8.80  ?  104  ILE B O    1 
ATOM   7194  C CB   . ILE B 1 138 ? 3.029   34.443  38.113 1.00 7.86  ?  104  ILE B CB   1 
ATOM   7195  C CG1  . ILE B 1 138 ? 3.510   33.563  39.269 1.00 9.57  ?  104  ILE B CG1  1 
ATOM   7196  C CG2  . ILE B 1 138 ? 2.406   33.574  37.009 1.00 8.41  ?  104  ILE B CG2  1 
ATOM   7197  C CD1  . ILE B 1 138 ? 2.408   32.893  40.037 1.00 7.76  ?  104  ILE B CD1  1 
ATOM   7198  H H    . ILE B 1 138 ? 4.257   36.419  39.158 1.00 10.18 ?  104  ILE B H    1 
ATOM   7199  H HA   . ILE B 1 138 ? 4.854   34.690  37.180 1.00 9.24  ?  104  ILE B HA   1 
ATOM   7200  H HB   . ILE B 1 138 ? 2.357   35.051  38.457 1.00 9.43  ?  104  ILE B HB   1 
ATOM   7201  H HG12 . ILE B 1 138 ? 4.084   32.868  38.911 1.00 11.48 ?  104  ILE B HG12 1 
ATOM   7202  H HG13 . ILE B 1 138 ? 4.008   34.116  39.892 1.00 11.48 ?  104  ILE B HG13 1 
ATOM   7203  H HG21 . ILE B 1 138 ? 1.741   32.990  37.404 1.00 10.09 ?  104  ILE B HG21 1 
ATOM   7204  H HG22 . ILE B 1 138 ? 1.990   34.151  36.350 1.00 10.09 ?  104  ILE B HG22 1 
ATOM   7205  H HG23 . ILE B 1 138 ? 3.104   33.045  36.591 1.00 10.09 ?  104  ILE B HG23 1 
ATOM   7206  H HD11 . ILE B 1 138 ? 2.787   32.456  40.816 1.00 9.31  ?  104  ILE B HD11 1 
ATOM   7207  H HD12 . ILE B 1 138 ? 1.763   33.562  40.315 1.00 9.31  ?  104  ILE B HD12 1 
ATOM   7208  H HD13 . ILE B 1 138 ? 1.979   32.237  39.466 1.00 9.31  ?  104  ILE B HD13 1 
ATOM   7209  N N    . ASN B 1 139 ? 4.023   35.828  35.185 1.00 8.60  ?  105  ASN B N    1 
ATOM   7210  C CA   . ASN B 1 139 ? 3.652   36.587  33.985 1.00 7.86  ?  105  ASN B CA   1 
ATOM   7211  C C    . ASN B 1 139 ? 2.330   36.063  33.410 1.00 7.46  ?  105  ASN B C    1 
ATOM   7212  O O    . ASN B 1 139 ? 2.287   35.439  32.349 1.00 9.04  ?  105  ASN B O    1 
ATOM   7213  C CB   . ASN B 1 139 ? 4.820   36.483  32.996 1.00 8.41  ?  105  ASN B CB   1 
ATOM   7214  C CG   . ASN B 1 139 ? 4.557   37.080  31.627 1.00 9.80  ?  105  ASN B CG   1 
ATOM   7215  O OD1  . ASN B 1 139 ? 5.046   36.547  30.624 1.00 10.61 ?  105  ASN B OD1  1 
ATOM   7216  N ND2  . ASN B 1 139 ? 3.871   38.212  31.567 1.00 10.75 ?  105  ASN B ND2  1 
ATOM   7217  H H    . ASN B 1 139 ? 4.490   35.129  35.004 1.00 10.32 ?  105  ASN B H    1 
ATOM   7218  H HA   . ASN B 1 139 ? 3.491   37.519  34.203 1.00 9.44  ?  105  ASN B HA   1 
ATOM   7219  H HB2  . ASN B 1 139 ? 5.584   36.947  33.372 1.00 10.09 ?  105  ASN B HB2  1 
ATOM   7220  H HB3  . ASN B 1 139 ? 5.032   35.545  32.867 1.00 10.09 ?  105  ASN B HB3  1 
ATOM   7221  H HD21 . ASN B 1 139 ? 3.706   38.575  30.805 1.00 12.90 ?  105  ASN B HD21 1 
ATOM   7222  H HD22 . ASN B 1 139 ? 3.591   38.584  32.290 1.00 12.90 ?  105  ASN B HD22 1 
ATOM   7223  N N    . TRP B 1 140 ? 1.241   36.302  34.157 1.00 8.04  ?  106  TRP B N    1 
ATOM   7224  C CA   . TRP B 1 140 ? -0.094  35.940  33.713 1.00 8.64  ?  106  TRP B CA   1 
ATOM   7225  C C    . TRP B 1 140 ? -0.506  36.762  32.486 1.00 8.12  ?  106  TRP B C    1 
ATOM   7226  O O    . TRP B 1 140 ? 0.003   37.860  32.221 1.00 8.26  ?  106  TRP B O    1 
ATOM   7227  C CB   . TRP B 1 140 ? -1.102  36.169  34.844 1.00 8.89  ?  106  TRP B CB   1 
ATOM   7228  C CG   . TRP B 1 140 ? -1.003  35.243  36.036 1.00 7.52  ?  106  TRP B CG   1 
ATOM   7229  C CD1  . TRP B 1 140 ? -0.698  35.595  37.319 1.00 7.95  ?  106  TRP B CD1  1 
ATOM   7230  C CD2  . TRP B 1 140 ? -1.247  33.831  36.061 1.00 7.29  ?  106  TRP B CD2  1 
ATOM   7231  N NE1  . TRP B 1 140 ? -0.741  34.488  38.142 1.00 7.76  ?  106  TRP B NE1  1 
ATOM   7232  C CE2  . TRP B 1 140 ? -1.072  33.394  37.389 1.00 8.31  ?  106  TRP B CE2  1 
ATOM   7233  C CE3  . TRP B 1 140 ? -1.597  32.888  35.088 1.00 8.30  ?  106  TRP B CE3  1 
ATOM   7234  C CZ2  . TRP B 1 140 ? -1.217  32.060  37.765 1.00 8.75  ?  106  TRP B CZ2  1 
ATOM   7235  C CZ3  . TRP B 1 140 ? -1.733  31.562  35.463 1.00 9.42  ?  106  TRP B CZ3  1 
ATOM   7236  C CH2  . TRP B 1 140 ? -1.549  31.163  36.788 1.00 8.84  ?  106  TRP B CH2  1 
ATOM   7237  H H    . TRP B 1 140 ? 1.258   36.677  34.931 1.00 9.65  ?  106  TRP B H    1 
ATOM   7238  H HA   . TRP B 1 140 ? -0.105  35.002  33.465 1.00 10.37 ?  106  TRP B HA   1 
ATOM   7239  H HB2  . TRP B 1 140 ? -0.983  37.072  35.176 1.00 10.66 ?  106  TRP B HB2  1 
ATOM   7240  H HB3  . TRP B 1 140 ? -1.994  36.065  34.478 1.00 10.66 ?  106  TRP B HB3  1 
ATOM   7241  H HD1  . TRP B 1 140 ? -0.492  36.458  37.599 1.00 9.54  ?  106  TRP B HD1  1 
ATOM   7242  H HE1  . TRP B 1 140 ? -0.585  34.486  38.988 1.00 9.31  ?  106  TRP B HE1  1 
ATOM   7243  H HE3  . TRP B 1 140 ? -1.736  33.146  34.205 1.00 9.96  ?  106  TRP B HE3  1 
ATOM   7244  H HZ2  . TRP B 1 140 ? -1.093  31.791  38.646 1.00 10.50 ?  106  TRP B HZ2  1 
ATOM   7245  H HZ3  . TRP B 1 140 ? -1.952  30.926  34.821 1.00 11.30 ?  106  TRP B HZ3  1 
ATOM   7246  H HH2  . TRP B 1 140 ? -1.655  30.266  37.012 1.00 10.61 ?  106  TRP B HH2  1 
ATOM   7247  N N    . GLY B 1 141 ? -1.445  36.211  31.727 1.00 8.07  ?  107  GLY B N    1 
ATOM   7248  C CA   . GLY B 1 141 ? -1.879  36.841  30.499 1.00 8.92  ?  107  GLY B CA   1 
ATOM   7249  C C    . GLY B 1 141 ? -2.790  38.038  30.690 1.00 8.50  ?  107  GLY B C    1 
ATOM   7250  O O    . GLY B 1 141 ? -3.242  38.371  31.779 1.00 8.11  ?  107  GLY B O    1 
ATOM   7251  H H    . GLY B 1 141 ? -1.845  35.471  31.905 1.00 9.69  ?  107  GLY B H    1 
ATOM   7252  H HA2  . GLY B 1 141 ? -1.097  37.139  30.008 1.00 10.71 ?  107  GLY B HA2  1 
ATOM   7253  H HA3  . GLY B 1 141 ? -2.357  36.187  29.965 1.00 10.71 ?  107  GLY B HA3  1 
ATOM   7254  N N    . ASN B 1 142 ? -3.070  38.679  29.562 1.00 8.51  ?  108  ASN B N    1 
ATOM   7255  C CA   . ASN B 1 142 ? -4.056  39.746  29.353 1.00 8.75  ?  108  ASN B CA   1 
ATOM   7256  C C    . ASN B 1 142 ? -3.626  41.126  29.827 1.00 8.89  ?  108  ASN B C    1 
ATOM   7257  O O    . ASN B 1 142 ? -4.480  42.028  29.846 1.00 10.11 ?  108  ASN B O    1 
ATOM   7258  C CB   . ASN B 1 142 ? -5.447  39.371  29.874 1.00 9.77  ?  108  ASN B CB   1 
ATOM   7259  C CG   . ASN B 1 142 ? -6.074  38.253  29.085 1.00 10.11 ?  108  ASN B CG   1 
ATOM   7260  O OD1  . ASN B 1 142 ? -5.945  38.208  27.855 1.00 13.15 ?  108  ASN B OD1  1 
ATOM   7261  N ND2  . ASN B 1 142 ? -6.750  37.354  29.768 1.00 10.67 ?  108  ASN B ND2  1 
ATOM   7262  H H    . ASN B 1 142 ? -2.662  38.496  28.827 1.00 10.21 ?  108  ASN B H    1 
ATOM   7263  H HA   . ASN B 1 142 ? -4.140  39.864  28.394 1.00 10.50 ?  108  ASN B HA   1 
ATOM   7264  H HB2  . ASN B 1 142 ? -5.373  39.084  30.797 1.00 11.73 ?  108  ASN B HB2  1 
ATOM   7265  H HB3  . ASN B 1 142 ? -6.028  40.145  29.812 1.00 11.73 ?  108  ASN B HB3  1 
ATOM   7266  H HD21 . ASN B 1 142 ? -7.126  36.697  29.360 1.00 12.80 ?  108  ASN B HD21 1 
ATOM   7267  H HD22 . ASN B 1 142 ? -6.816  37.424  30.623 1.00 12.80 ?  108  ASN B HD22 1 
ATOM   7268  N N    . TYR B 1 143 ? -2.350  41.342  30.133 1.00 8.34  ?  109  TYR B N    1 
ATOM   7269  C CA   . TYR B 1 143 ? -1.788  42.677  30.323 1.00 9.05  ?  109  TYR B CA   1 
ATOM   7270  C C    . TYR B 1 143 ? -1.158  43.102  29.003 1.00 10.03 ?  109  TYR B C    1 
ATOM   7271  O O    . TYR B 1 143 ? -0.092  42.593  28.630 1.00 10.65 ?  109  TYR B O    1 
ATOM   7272  C CB   . TYR B 1 143 ? -0.731  42.685  31.421 1.00 8.99  ?  109  TYR B CB   1 
ATOM   7273  C CG   . TYR B 1 143 ? -1.248  42.359  32.804 1.00 8.67  ?  109  TYR B CG   1 
ATOM   7274  C CD1  . TYR B 1 143 ? -1.847  43.333  33.601 1.00 8.53  ?  109  TYR B CD1  1 
ATOM   7275  C CD2  . TYR B 1 143 ? -1.148  41.080  33.304 1.00 8.63  ?  109  TYR B CD2  1 
ATOM   7276  C CE1  . TYR B 1 143 ? -2.300  43.041  34.867 1.00 9.05  ?  109  TYR B CE1  1 
ATOM   7277  C CE2  . TYR B 1 143 ? -1.600  40.772  34.563 1.00 8.65  ?  109  TYR B CE2  1 
ATOM   7278  C CZ   . TYR B 1 143 ? -2.185  41.753  35.344 1.00 8.19  ?  109  TYR B CZ   1 
ATOM   7279  O OH   . TYR B 1 143 ? -2.619  41.428  36.618 1.00 7.99  ?  109  TYR B OH   1 
ATOM   7280  H H    . TYR B 1 143 ? -1.773  40.713  30.240 1.00 10.01 ?  109  TYR B H    1 
ATOM   7281  H HA   . TYR B 1 143 ? -2.499  43.288  30.572 1.00 10.86 ?  109  TYR B HA   1 
ATOM   7282  H HB2  . TYR B 1 143 ? -0.054  42.027  31.200 1.00 10.79 ?  109  TYR B HB2  1 
ATOM   7283  H HB3  . TYR B 1 143 ? -0.335  43.570  31.459 1.00 10.79 ?  109  TYR B HB3  1 
ATOM   7284  H HD1  . TYR B 1 143 ? -1.942  44.198  33.271 1.00 10.24 ?  109  TYR B HD1  1 
ATOM   7285  H HD2  . TYR B 1 143 ? -0.768  40.413  32.779 1.00 10.36 ?  109  TYR B HD2  1 
ATOM   7286  H HE1  . TYR B 1 143 ? -2.679  43.705  35.395 1.00 10.86 ?  109  TYR B HE1  1 
ATOM   7287  H HE2  . TYR B 1 143 ? -1.512  39.906  34.891 1.00 10.39 ?  109  TYR B HE2  1 
ATOM   7288  H HH   . TYR B 1 143 ? -2.881  42.119  37.018 1.00 9.59  ?  109  TYR B HH   1 
ATOM   7289  N N    . LYS B 1 144 ? -1.792  44.050  28.300 1.00 9.81  ?  110  LYS B N    1 
ATOM   7290  C CA   . LYS B 1 144 ? -1.237  44.449  27.006 1.00 10.26 ?  110  LYS B CA   1 
ATOM   7291  C C    . LYS B 1 144 ? 0.177   45.006  27.148 1.00 10.86 ?  110  LYS B C    1 
ATOM   7292  O O    . LYS B 1 144 ? 1.023   44.770  26.274 1.00 11.60 ?  110  LYS B O    1 
ATOM   7293  C CB   . LYS B 1 144 ? -2.149  45.436  26.286 1.00 13.32 ?  110  LYS B CB   1 
ATOM   7294  C CG   . LYS B 1 144 ? -2.284  46.768  26.930 1.00 15.86 ?  110  LYS B CG   1 
ATOM   7295  C CD   . LYS B 1 144 ? -3.120  47.687  26.040 1.00 15.54 ?  110  LYS B CD   1 
ATOM   7296  C CE   . LYS B 1 144 ? -3.372  49.018  26.702 1.00 20.14 ?  110  LYS B CE   1 
ATOM   7297  N NZ   . LYS B 1 144 ? -2.137  49.848  26.814 1.00 24.32 ?  110  LYS B NZ   1 
ATOM   7298  H H    . LYS B 1 144 ? -2.511  44.457  28.541 1.00 11.78 ?  110  LYS B H    1 
ATOM   7299  H HA   . LYS B 1 144 ? -1.191  43.661  26.443 1.00 12.32 ?  110  LYS B HA   1 
ATOM   7300  H HB2  . LYS B 1 144 ? -1.798  45.581  25.394 1.00 15.98 ?  110  LYS B HB2  1 
ATOM   7301  H HB3  . LYS B 1 144 ? -3.037  45.049  26.235 1.00 15.98 ?  110  LYS B HB3  1 
ATOM   7302  H HG2  . LYS B 1 144 ? -2.728  46.675  27.787 1.00 19.03 ?  110  LYS B HG2  1 
ATOM   7303  H HG3  . LYS B 1 144 ? -1.407  47.165  27.052 1.00 19.03 ?  110  LYS B HG3  1 
ATOM   7304  H HD2  . LYS B 1 144 ? -2.647  47.846  25.208 1.00 18.64 ?  110  LYS B HD2  1 
ATOM   7305  H HD3  . LYS B 1 144 ? -3.976  47.269  25.860 1.00 18.64 ?  110  LYS B HD3  1 
ATOM   7306  H HE2  . LYS B 1 144 ? -4.021  49.514  26.179 1.00 24.17 ?  110  LYS B HE2  1 
ATOM   7307  H HE3  . LYS B 1 144 ? -3.714  48.866  27.597 1.00 24.17 ?  110  LYS B HE3  1 
ATOM   7308  H HZ1  . LYS B 1 144 ? -2.331  50.634  27.183 1.00 29.18 ?  110  LYS B HZ1  1 
ATOM   7309  H HZ2  . LYS B 1 144 ? -1.535  49.432  27.320 1.00 29.18 ?  110  LYS B HZ2  1 
ATOM   7310  H HZ3  . LYS B 1 144 ? -1.789  49.986  26.006 1.00 29.18 ?  110  LYS B HZ3  1 
ATOM   7311  N N    . ASN B 1 145 ? 0.473   45.714  28.238 1.00 9.92  ?  111  ASN B N    1 
ATOM   7312  C CA   . ASN B 1 145 ? 1.796   46.315  28.356 1.00 11.15 ?  111  ASN B CA   1 
ATOM   7313  C C    . ASN B 1 145 ? 2.840   45.260  28.681 1.00 10.73 ?  111  ASN B C    1 
ATOM   7314  O O    . ASN B 1 145 ? 3.993   45.364  28.239 1.00 11.64 ?  111  ASN B O    1 
ATOM   7315  C CB   . ASN B 1 145 ? 1.815   47.426  29.406 1.00 11.25 ?  111  ASN B CB   1 
ATOM   7316  C CG   . ASN B 1 145 ? 0.922   48.592  29.034 1.00 12.46 ?  111  ASN B CG   1 
ATOM   7317  O OD1  . ASN B 1 145 ? 0.548   48.760  27.872 1.00 14.46 ?  111  ASN B OD1  1 
ATOM   7318  N ND2  . ASN B 1 145 ? 0.548   49.390  30.026 1.00 12.60 ?  111  ASN B ND2  1 
ATOM   7319  H H    . ASN B 1 145 ? -0.057  45.856  28.900 1.00 11.90 ?  111  ASN B H    1 
ATOM   7320  H HA   . ASN B 1 145 ? 2.024   46.736  27.512 1.00 13.38 ?  111  ASN B HA   1 
ATOM   7321  H HB2  . ASN B 1 145 ? 1.505   47.068  30.252 1.00 13.51 ?  111  ASN B HB2  1 
ATOM   7322  H HB3  . ASN B 1 145 ? 2.721   47.759  29.498 1.00 13.51 ?  111  ASN B HB3  1 
ATOM   7323  H HD21 . ASN B 1 145 ? 0.041   50.066  29.866 1.00 15.12 ?  111  ASN B HD21 1 
ATOM   7324  H HD22 . ASN B 1 145 ? 0.812   49.231  30.829 1.00 15.12 ?  111  ASN B HD22 1 
ATOM   7325  N N    . ASP B 1 146 ? 2.461   44.231  29.446 1.00 10.08 ?  112  ASP B N    1 
ATOM   7326  C CA   . ASP B 1 146 ? 3.397   43.146  29.701 1.00 10.36 ?  112  ASP B CA   1 
ATOM   7327  C C    . ASP B 1 146 ? 3.672   42.362  28.425 1.00 11.28 ?  112  ASP B C    1 
ATOM   7328  O O    . ASP B 1 146 ? 4.825   41.997  28.154 1.00 11.16 ?  112  ASP B O    1 
ATOM   7329  C CB   . ASP B 1 146 ? 2.843   42.170  30.734 1.00 9.38  ?  112  ASP B CB   1 
ATOM   7330  C CG   . ASP B 1 146 ? 2.660   42.781  32.112 1.00 9.77  ?  112  ASP B CG   1 
ATOM   7331  O OD1  . ASP B 1 146 ? 2.876   44.004  32.320 1.00 10.10 ?  112  ASP B OD1  1 
ATOM   7332  O OD2  . ASP B 1 146 ? 2.248   42.021  33.005 1.00 9.51  ?  112  ASP B OD2  1 
ATOM   7333  H H    . ASP B 1 146 ? 1.689   44.144  29.815 1.00 12.09 ?  112  ASP B H    1 
ATOM   7334  H HA   . ASP B 1 146 ? 4.213   43.542  30.045 1.00 12.44 ?  112  ASP B HA   1 
ATOM   7335  H HB2  . ASP B 1 146 ? 1.977   41.854  30.434 1.00 11.26 ?  112  ASP B HB2  1 
ATOM   7336  H HB3  . ASP B 1 146 ? 3.457   41.424  30.820 1.00 11.26 ?  112  ASP B HB3  1 
ATOM   7337  N N    . ASP B 1 147 ? 2.636   42.091  27.628 1.00 10.61 ?  113  ASP B N    1 
ATOM   7338  C CA   . ASP B 1 147 ? 2.843   41.365  26.374 1.00 12.39 ?  113  ASP B CA   1 
ATOM   7339  C C    . ASP B 1 147 ? 3.817   42.120  25.466 1.00 12.61 ?  113  ASP B C    1 
ATOM   7340  O O    . ASP B 1 147 ? 4.720   41.522  24.873 1.00 13.17 ?  113  ASP B O    1 
ATOM   7341  C CB   . ASP B 1 147 ? 1.515   41.128  25.649 1.00 11.43 ?  113  ASP B CB   1 
ATOM   7342  C CG   . ASP B 1 147 ? 0.585   40.193  26.386 1.00 11.85 ?  113  ASP B CG   1 
ATOM   7343  O OD1  . ASP B 1 147 ? 0.983   39.597  27.409 1.00 12.14 ?  113  ASP B OD1  1 
ATOM   7344  O OD2  . ASP B 1 147 ? -0.558  40.033  25.907 1.00 15.20 ?  113  ASP B OD2  1 
ATOM   7345  H H    . ASP B 1 147 ? 1.820   42.311  27.787 1.00 12.73 ?  113  ASP B H    1 
ATOM   7346  H HA   . ASP B 1 147 ? 3.218   40.495  26.582 1.00 14.87 ?  113  ASP B HA   1 
ATOM   7347  H HB2  . ASP B 1 147 ? 1.059   41.978  25.545 1.00 13.72 ?  113  ASP B HB2  1 
ATOM   7348  H HB3  . ASP B 1 147 ? 1.697   40.740  24.779 1.00 13.72 ?  113  ASP B HB3  1 
ATOM   7349  N N    . GLU B 1 148 ? 3.682   43.443  25.389 1.00 11.57 ?  114  GLU B N    1 
ATOM   7350  C CA   . GLU B 1 148 ? 4.592   44.234  24.564 1.00 12.76 ?  114  GLU B CA   1 
ATOM   7351  C C    . GLU B 1 148 ? 6.010   44.190  25.126 1.00 15.04 ?  114  GLU B C    1 
ATOM   7352  O O    . GLU B 1 148 ? 6.984   44.006  24.380 1.00 15.71 ?  114  GLU B O    1 
ATOM   7353  C CB   . GLU B 1 148 ? 4.075   45.669  24.504 1.00 14.91 ?  114  GLU B CB   1 
ATOM   7354  C CG   . GLU B 1 148 ? 5.083   46.679  23.985 1.00 20.79 ?  114  GLU B CG   1 
ATOM   7355  C CD   . GLU B 1 148 ? 4.500   48.079  23.909 1.00 28.43 ?  114  GLU B CD   1 
ATOM   7356  O OE1  . GLU B 1 148 ? 4.082   48.597  24.965 1.00 22.75 ?  114  GLU B OE1  1 
ATOM   7357  O OE2  . GLU B 1 148 ? 4.467   48.665  22.804 1.00 30.54 ?  114  GLU B OE2  1 
ATOM   7358  H H    . GLU B 1 148 ? 3.080   43.901  25.798 1.00 13.89 ?  114  GLU B H    1 
ATOM   7359  H HA   . GLU B 1 148 ? 4.621   43.874  23.664 1.00 15.31 ?  114  GLU B HA   1 
ATOM   7360  H HB2  . GLU B 1 148 ? 3.304   45.695  23.916 1.00 17.89 ?  114  GLU B HB2  1 
ATOM   7361  H HB3  . GLU B 1 148 ? 3.820   45.943  25.399 1.00 17.89 ?  114  GLU B HB3  1 
ATOM   7362  H HG2  . GLU B 1 148 ? 5.848   46.702  24.581 1.00 24.95 ?  114  GLU B HG2  1 
ATOM   7363  H HG3  . GLU B 1 148 ? 5.365   46.420  23.094 1.00 24.95 ?  114  GLU B HG3  1 
ATOM   7364  N N    . PHE B 1 149 ? 6.148   44.362  26.440 1.00 12.55 ?  115  PHE B N    1 
ATOM   7365  C CA   . PHE B 1 149 ? 7.453   44.357  27.101 1.00 13.10 ?  115  PHE B CA   1 
ATOM   7366  C C    . PHE B 1 149 ? 8.163   43.024  26.928 1.00 15.93 ?  115  PHE B C    1 
ATOM   7367  O O    . PHE B 1 149 ? 9.369   42.982  26.643 1.00 15.35 ?  115  PHE B O    1 
ATOM   7368  C CB   . PHE B 1 149 ? 7.235   44.663  28.589 1.00 13.19 ?  115  PHE B CB   1 
ATOM   7369  C CG   . PHE B 1 149 ? 8.465   44.570  29.443 1.00 11.86 ?  115  PHE B CG   1 
ATOM   7370  C CD1  . PHE B 1 149 ? 9.491   45.482  29.323 1.00 14.25 ?  115  PHE B CD1  1 
ATOM   7371  C CD2  . PHE B 1 149 ? 8.586   43.569  30.384 1.00 12.83 ?  115  PHE B CD2  1 
ATOM   7372  C CE1  . PHE B 1 149 ? 10.611  45.390  30.129 1.00 14.64 ?  115  PHE B CE1  1 
ATOM   7373  C CE2  . PHE B 1 149 ? 9.695   43.473  31.172 1.00 13.21 ?  115  PHE B CE2  1 
ATOM   7374  C CZ   . PHE B 1 149 ? 10.711  44.387  31.043 1.00 14.97 ?  115  PHE B CZ   1 
ATOM   7375  H H    . PHE B 1 149 ? 5.492   44.486  26.982 1.00 15.06 ?  115  PHE B H    1 
ATOM   7376  H HA   . PHE B 1 149 ? 8.022   45.037  26.707 1.00 15.72 ?  115  PHE B HA   1 
ATOM   7377  H HB2  . PHE B 1 149 ? 6.893   45.568  28.670 1.00 15.82 ?  115  PHE B HB2  1 
ATOM   7378  H HB3  . PHE B 1 149 ? 6.588   44.032  28.941 1.00 15.82 ?  115  PHE B HB3  1 
ATOM   7379  H HD1  . PHE B 1 149 ? 9.430   46.165  28.695 1.00 17.10 ?  115  PHE B HD1  1 
ATOM   7380  H HD2  . PHE B 1 149 ? 7.900   42.949  30.483 1.00 15.39 ?  115  PHE B HD2  1 
ATOM   7381  H HE1  . PHE B 1 149 ? 11.296  46.014  30.046 1.00 17.57 ?  115  PHE B HE1  1 
ATOM   7382  H HE2  . PHE B 1 149 ? 9.763   42.788  31.797 1.00 15.85 ?  115  PHE B HE2  1 
ATOM   7383  H HZ   . PHE B 1 149 ? 11.467  44.320  31.580 1.00 17.97 ?  115  PHE B HZ   1 
ATOM   7384  N N    . ILE B 1 150 ? 7.441   41.920  27.119 1.00 13.57 ?  116  ILE B N    1 
ATOM   7385  C CA   . ILE B 1 150 ? 8.048   40.593  27.020 1.00 13.18 ?  116  ILE B CA   1 
ATOM   7386  C C    . ILE B 1 150 ? 8.378   40.248  25.571 1.00 17.53 ?  116  ILE B C    1 
ATOM   7387  O O    . ILE B 1 150 ? 9.388   39.588  25.299 1.00 18.99 ?  116  ILE B O    1 
ATOM   7388  C CB   . ILE B 1 150 ? 7.113   39.551  27.657 1.00 13.22 ?  116  ILE B CB   1 
ATOM   7389  C CG1  . ILE B 1 150 ? 6.966   39.774  29.167 1.00 14.15 ?  116  ILE B CG1  1 
ATOM   7390  C CG2  . ILE B 1 150 ? 7.601   38.119  27.387 1.00 17.19 ?  116  ILE B CG2  1 
ATOM   7391  C CD1  . ILE B 1 150 ? 8.249   39.817  29.952 1.00 15.29 ?  116  ILE B CD1  1 
ATOM   7392  H H    . ILE B 1 150 ? 6.601   41.912  27.307 1.00 16.28 ?  116  ILE B H    1 
ATOM   7393  H HA   . ILE B 1 150 ? 8.885   40.597  27.510 1.00 15.81 ?  116  ILE B HA   1 
ATOM   7394  H HB   . ILE B 1 150 ? 6.244   39.667  27.241 1.00 15.86 ?  116  ILE B HB   1 
ATOM   7395  H HG12 . ILE B 1 150 ? 6.515   40.621  29.306 1.00 16.98 ?  116  ILE B HG12 1 
ATOM   7396  H HG13 . ILE B 1 150 ? 6.432   39.050  29.530 1.00 16.98 ?  116  ILE B HG13 1 
ATOM   7397  H HG21 . ILE B 1 150 ? 7.080   37.501  27.924 1.00 20.63 ?  116  ILE B HG21 1 
ATOM   7398  H HG22 . ILE B 1 150 ? 7.486   37.918  26.445 1.00 20.63 ?  116  ILE B HG22 1 
ATOM   7399  H HG23 . ILE B 1 150 ? 8.539   38.055  27.626 1.00 20.63 ?  116  ILE B HG23 1 
ATOM   7400  H HD11 . ILE B 1 150 ? 8.039   39.834  30.899 1.00 18.34 ?  116  ILE B HD11 1 
ATOM   7401  H HD12 . ILE B 1 150 ? 8.774   39.029  29.743 1.00 18.34 ?  116  ILE B HD12 1 
ATOM   7402  H HD13 . ILE B 1 150 ? 8.741   40.617  29.708 1.00 18.34 ?  116  ILE B HD13 1 
ATOM   7403  N N    . SER B 1 151 ? 7.530   40.646  24.618 1.00 17.45 ?  117  SER B N    1 
ATOM   7404  C CA   . SER B 1 151 ? 7.859   40.442  23.209 1.00 20.44 ?  117  SER B CA   1 
ATOM   7405  C C    . SER B 1 151 ? 9.150   41.162  22.837 1.00 20.62 ?  117  SER B C    1 
ATOM   7406  O O    . SER B 1 151 ? 10.006  40.592  22.145 1.00 24.15 ?  117  SER B O    1 
ATOM   7407  C CB   . SER B 1 151 ? 6.707   40.900  22.315 1.00 20.53 ?  117  SER B CB   1 
ATOM   7408  O OG   . SER B 1 151 ? 5.628   39.984  22.348 1.00 30.16 ?  117  SER B OG   1 
ATOM   7409  H H    . SER B 1 151 ? 6.773   41.029  24.760 1.00 20.94 ?  117  SER B H    1 
ATOM   7410  H HA   . SER B 1 151 ? 7.987   39.492  23.057 1.00 24.53 ?  117  SER B HA   1 
ATOM   7411  H HB2  . SER B 1 151 ? 6.394   41.764  22.626 1.00 24.64 ?  117  SER B HB2  1 
ATOM   7412  H HB3  . SER B 1 151 ? 7.029   40.973  21.403 1.00 24.64 ?  117  SER B HB3  1 
ATOM   7413  H HG   . SER B 1 151 ? 4.923   40.361  22.089 1.00 36.19 ?  117  SER B HG   1 
ATOM   7414  N N    . LYS B 1 152 ? 9.315   42.410  23.286 1.00 17.14 ?  118  LYS B N    1 
ATOM   7415  C CA   . LYS B 1 152 ? 10.518  43.172  22.964 1.00 19.13 ?  118  LYS B CA   1 
ATOM   7416  C C    . LYS B 1 152 ? 11.731  42.675  23.730 1.00 24.87 ?  118  LYS B C    1 
ATOM   7417  O O    . LYS B 1 152 ? 12.856  42.773  23.226 1.00 22.10 ?  118  LYS B O    1 
ATOM   7418  C CB   . LYS B 1 152 ? 10.306  44.669  23.205 1.00 21.54 ?  118  LYS B CB   1 
ATOM   7419  C CG   . LYS B 1 152 ? 9.157   45.265  22.387 1.00 40.85 ?  118  LYS B CG   1 
ATOM   7420  C CD   . LYS B 1 152 ? 8.887   46.732  22.718 1.00 39.35 ?  118  LYS B CD   1 
ATOM   7421  C CE   . LYS B 1 152 ? 8.065   47.438  21.625 1.00 43.44 ?  118  LYS B CE   1 
ATOM   7422  N NZ   . LYS B 1 152 ? 7.349   46.510  20.704 1.00 31.28 ?  118  LYS B NZ   1 
ATOM   7423  H H    . LYS B 1 152 ? 8.748   42.833  23.775 1.00 20.57 ?  118  LYS B H    1 
ATOM   7424  H HA   . LYS B 1 152 ? 10.695  43.056  22.017 1.00 22.96 ?  118  LYS B HA   1 
ATOM   7425  H HB2  . LYS B 1 152 ? 10.106  44.810  24.143 1.00 25.84 ?  118  LYS B HB2  1 
ATOM   7426  H HB3  . LYS B 1 152 ? 11.118  45.142  22.964 1.00 25.84 ?  118  LYS B HB3  1 
ATOM   7427  H HG2  . LYS B 1 152 ? 9.378   45.208  21.444 1.00 49.02 ?  118  LYS B HG2  1 
ATOM   7428  H HG3  . LYS B 1 152 ? 8.347   44.764  22.569 1.00 49.02 ?  118  LYS B HG3  1 
ATOM   7429  H HD2  . LYS B 1 152 ? 8.390   46.785  23.549 1.00 47.21 ?  118  LYS B HD2  1 
ATOM   7430  H HD3  . LYS B 1 152 ? 9.732   47.199  22.807 1.00 47.21 ?  118  LYS B HD3  1 
ATOM   7431  H HE2  . LYS B 1 152 ? 7.400   48.000  22.051 1.00 52.13 ?  118  LYS B HE2  1 
ATOM   7432  H HE3  . LYS B 1 152 ? 8.664   47.980  21.088 1.00 52.13 ?  118  LYS B HE3  1 
ATOM   7433  H HZ1  . LYS B 1 152 ? 6.885   46.975  20.104 1.00 37.54 ?  118  LYS B HZ1  1 
ATOM   7434  H HZ2  . LYS B 1 152 ? 7.933   45.991  20.279 1.00 37.54 ?  118  LYS B HZ2  1 
ATOM   7435  H HZ3  . LYS B 1 152 ? 6.788   45.996  21.166 1.00 37.54 ?  118  LYS B HZ3  1 
ATOM   7436  N N    . ASN B 1 153 ? 11.528  42.121  24.924 1.00 18.67 ?  119  ASN B N    1 
ATOM   7437  C CA   . ASN B 1 153 ? 12.617  41.748  25.825 1.00 17.81 ?  119  ASN B CA   1 
ATOM   7438  C C    . ASN B 1 153 ? 12.406  40.328  26.321 1.00 19.43 ?  119  ASN B C    1 
ATOM   7439  O O    . ASN B 1 153 ? 12.078  40.105  27.491 1.00 16.16 ?  119  ASN B O    1 
ATOM   7440  C CB   . ASN B 1 153 ? 12.702  42.711  27.007 1.00 17.58 ?  119  ASN B CB   1 
ATOM   7441  C CG   . ASN B 1 153 ? 12.796  44.153  26.582 1.00 21.24 ?  119  ASN B CG   1 
ATOM   7442  O OD1  . ASN B 1 153 ? 13.859  44.614  26.159 1.00 25.76 ?  119  ASN B OD1  1 
ATOM   7443  N ND2  . ASN B 1 153 ? 11.694  44.883  26.691 1.00 19.53 ?  119  ASN B ND2  1 
ATOM   7444  H H    . ASN B 1 153 ? 10.748  41.947  25.241 1.00 22.40 ?  119  ASN B H    1 
ATOM   7445  H HA   . ASN B 1 153 ? 13.450  41.779  25.328 1.00 21.37 ?  119  ASN B HA   1 
ATOM   7446  H HB2  . ASN B 1 153 ? 11.907  42.611  27.553 1.00 21.10 ?  119  ASN B HB2  1 
ATOM   7447  H HB3  . ASN B 1 153 ? 13.492  42.501  27.529 1.00 21.10 ?  119  ASN B HB3  1 
ATOM   7448  H HD21 . ASN B 1 153 ? 11.702  45.711  26.460 1.00 23.43 ?  119  ASN B HD21 1 
ATOM   7449  H HD22 . ASN B 1 153 ? 10.971  44.527  26.993 1.00 23.43 ?  119  ASN B HD22 1 
ATOM   7450  N N    . PRO B 1 154 ? 12.606  39.333  25.458 1.00 16.42 ?  120  PRO B N    1 
ATOM   7451  C CA   . PRO B 1 154 ? 12.454  37.940  25.901 1.00 14.78 ?  120  PRO B CA   1 
ATOM   7452  C C    . PRO B 1 154 ? 13.376  37.572  27.052 1.00 14.82 ?  120  PRO B C    1 
ATOM   7453  O O    . PRO B 1 154 ? 13.072  36.634  27.805 1.00 15.99 ?  120  PRO B O    1 
ATOM   7454  C CB   . PRO B 1 154 ? 12.743  37.126  24.630 1.00 19.73 ?  120  PRO B CB   1 
ATOM   7455  C CG   . PRO B 1 154 ? 13.470  38.089  23.719 1.00 24.82 ?  120  PRO B CG   1 
ATOM   7456  C CD   . PRO B 1 154 ? 12.941  39.443  24.028 1.00 21.82 ?  120  PRO B CD   1 
ATOM   7457  H HA   . PRO B 1 154 ? 11.538  37.767  26.169 1.00 17.74 ?  120  PRO B HA   1 
ATOM   7458  H HB2  . PRO B 1 154 ? 13.300  36.361  24.845 1.00 23.68 ?  120  PRO B HB2  1 
ATOM   7459  H HB3  . PRO B 1 154 ? 11.911  36.828  24.230 1.00 23.68 ?  120  PRO B HB3  1 
ATOM   7460  H HG2  . PRO B 1 154 ? 14.423  38.046  23.896 1.00 29.78 ?  120  PRO B HG2  1 
ATOM   7461  H HG3  . PRO B 1 154 ? 13.294  37.856  22.794 1.00 29.78 ?  120  PRO B HG3  1 
ATOM   7462  H HD2  . PRO B 1 154 ? 13.616  40.123  23.880 1.00 26.19 ?  120  PRO B HD2  1 
ATOM   7463  H HD3  . PRO B 1 154 ? 12.151  39.638  23.499 1.00 26.19 ?  120  PRO B HD3  1 
ATOM   7464  N N    . SER B 1 155 ? 14.480  38.311  27.245 1.00 16.35 ?  121  SER B N    1 
ATOM   7465  C CA   . SER B 1 155 ? 15.347  38.036  28.374 1.00 14.02 ?  121  SER B CA   1 
ATOM   7466  C C    . SER B 1 155 ? 14.747  38.480  29.694 1.00 13.42 ?  121  SER B C    1 
ATOM   7467  O O    . SER B 1 155 ? 15.332  38.197  30.741 1.00 13.96 ?  121  SER B O    1 
ATOM   7468  C CB   . SER B 1 155 ? 16.703  38.711  28.187 1.00 15.35 ?  121  SER B CB   1 
ATOM   7469  O OG   . SER B 1 155 ? 16.577  40.112  28.279 1.00 20.41 ?  121  SER B OG   1 
ATOM   7470  H H    . SER B 1 155 ? 14.734  38.960  26.742 1.00 19.62 ?  121  SER B H    1 
ATOM   7471  H HA   . SER B 1 155 ? 15.496  37.079  28.411 1.00 16.83 ?  121  SER B HA   1 
ATOM   7472  H HB2  . SER B 1 155 ? 17.309  38.402  28.879 1.00 18.43 ?  121  SER B HB2  1 
ATOM   7473  H HB3  . SER B 1 155 ? 17.053  38.482  27.312 1.00 18.43 ?  121  SER B HB3  1 
ATOM   7474  H HG   . SER B 1 155 ? 17.299  40.449  28.547 1.00 24.50 ?  121  SER B HG   1 
ATOM   7475  N N    . ALA B 1 156 ? 13.575  39.118  29.667 1.00 12.52 ?  122  ALA B N    1 
ATOM   7476  C CA   . ALA B 1 156 ? 12.902  39.481  30.906 1.00 12.36 ?  122  ALA B CA   1 
ATOM   7477  C C    . ALA B 1 156 ? 12.299  38.285  31.630 1.00 12.92 ?  122  ALA B C    1 
ATOM   7478  O O    . ALA B 1 156 ? 11.961  38.407  32.817 1.00 12.31 ?  122  ALA B O    1 
ATOM   7479  C CB   . ALA B 1 156 ? 11.780  40.478  30.619 1.00 12.80 ?  122  ALA B CB   1 
ATOM   7480  H H    . ALA B 1 156 ? 13.158  39.348  28.951 1.00 15.02 ?  122  ALA B H    1 
ATOM   7481  H HA   . ALA B 1 156 ? 13.557  39.897  31.488 1.00 14.83 ?  122  ALA B HA   1 
ATOM   7482  H HB1  . ALA B 1 156 ? 11.334  40.700  31.451 1.00 15.36 ?  122  ALA B HB1  1 
ATOM   7483  H HB2  . ALA B 1 156 ? 12.161  41.278  30.224 1.00 15.36 ?  122  ALA B HB2  1 
ATOM   7484  H HB3  . ALA B 1 156 ? 11.148  40.075  30.003 1.00 15.36 ?  122  ALA B HB3  1 
ATOM   7485  N N    . LEU B 1 157 ? 12.179  37.138  30.966 1.00 11.07 ?  123  LEU B N    1 
ATOM   7486  C CA   . LEU B 1 157 ? 11.578  35.965  31.571 1.00 13.20 ?  123  LEU B CA   1 
ATOM   7487  C C    . LEU B 1 157 ? 12.629  35.071  32.209 1.00 13.26 ?  123  LEU B C    1 
ATOM   7488  O O    . LEU B 1 157 ? 13.763  34.952  31.729 1.00 14.55 ?  123  LEU B O    1 
ATOM   7489  C CB   . LEU B 1 157 ? 10.808  35.156  30.538 1.00 12.81 ?  123  LEU B CB   1 
ATOM   7490  C CG   . LEU B 1 157 ? 9.585   35.875  29.983 1.00 12.62 ?  123  LEU B CG   1 
ATOM   7491  C CD1  . LEU B 1 157 ? 8.873   35.007  28.965 1.00 15.02 ?  123  LEU B CD1  1 
ATOM   7492  C CD2  . LEU B 1 157 ? 8.621   36.290  31.095 1.00 14.34 ?  123  LEU B CD2  1 
ATOM   7493  H H    . LEU B 1 157 ? 12.443  37.018  30.157 1.00 13.28 ?  123  LEU B H    1 
ATOM   7494  H HA   . LEU B 1 157 ? 10.964  36.260  32.263 1.00 15.84 ?  123  LEU B HA   1 
ATOM   7495  H HB2  . LEU B 1 157 ? 11.399  34.958  29.795 1.00 15.37 ?  123  LEU B HB2  1 
ATOM   7496  H HB3  . LEU B 1 157 ? 10.506  34.332  30.950 1.00 15.37 ?  123  LEU B HB3  1 
ATOM   7497  H HG   . LEU B 1 157 ? 9.886   36.684  29.541 1.00 15.14 ?  123  LEU B HG   1 
ATOM   7498  H HD11 . LEU B 1 157 ? 8.132   35.506  28.588 1.00 18.02 ?  123  LEU B HD11 1 
ATOM   7499  H HD12 . LEU B 1 157 ? 9.499   34.765  28.264 1.00 18.02 ?  123  LEU B HD12 1 
ATOM   7500  H HD13 . LEU B 1 157 ? 8.544   34.208  29.406 1.00 18.02 ?  123  LEU B HD13 1 
ATOM   7501  H HD21 . LEU B 1 157 ? 7.775   36.551  30.699 1.00 17.20 ?  123  LEU B HD21 1 
ATOM   7502  H HD22 . LEU B 1 157 ? 8.488   35.539  31.694 1.00 17.20 ?  123  LEU B HD22 1 
ATOM   7503  H HD23 . LEU B 1 157 ? 9.003   37.037  31.581 1.00 17.20 ?  123  LEU B HD23 1 
ATOM   7504  N N    . LEU B 1 158 ? 12.225  34.413  33.282 1.00 11.11 ?  124  LEU B N    1 
ATOM   7505  C CA   . LEU B 1 158 ? 13.120  33.596  34.091 1.00 9.35  ?  124  LEU B CA   1 
ATOM   7506  C C    . LEU B 1 158 ? 13.467  32.280  33.407 1.00 12.06 ?  124  LEU B C    1 
ATOM   7507  O O    . LEU B 1 158 ? 12.588  31.529  32.966 1.00 12.03 ?  124  LEU B O    1 
ATOM   7508  C CB   . LEU B 1 158 ? 12.448  33.306  35.436 1.00 10.07 ?  124  LEU B CB   1 
ATOM   7509  C CG   . LEU B 1 158 ? 13.244  32.500  36.456 1.00 11.23 ?  124  LEU B CG   1 
ATOM   7510  C CD1  . LEU B 1 158 ? 14.497  33.259  36.889 1.00 12.53 ?  124  LEU B CD1  1 
ATOM   7511  C CD2  . LEU B 1 158 ? 12.400  32.177  37.662 1.00 11.33 ?  124  LEU B CD2  1 
ATOM   7512  H H    . LEU B 1 158 ? 11.416  34.421  33.574 1.00 13.33 ?  124  LEU B H    1 
ATOM   7513  H HA   . LEU B 1 158 ? 13.949  34.080  34.224 1.00 11.21 ?  124  LEU B HA   1 
ATOM   7514  H HB2  . LEU B 1 158 ? 12.237  34.157  35.852 1.00 12.08 ?  124  LEU B HB2  1 
ATOM   7515  H HB3  . LEU B 1 158 ? 11.632  32.812  35.260 1.00 12.08 ?  124  LEU B HB3  1 
ATOM   7516  H HG   . LEU B 1 158 ? 13.516  31.667  36.040 1.00 13.48 ?  124  LEU B HG   1 
ATOM   7517  H HD11 . LEU B 1 158 ? 14.971  32.734  37.553 1.00 15.04 ?  124  LEU B HD11 1 
ATOM   7518  H HD12 . LEU B 1 158 ? 15.063  33.402  36.114 1.00 15.04 ?  124  LEU B HD12 1 
ATOM   7519  H HD13 . LEU B 1 158 ? 14.234  34.112  37.269 1.00 15.04 ?  124  LEU B HD13 1 
ATOM   7520  H HD21 . LEU B 1 158 ? 12.936  31.678  38.298 1.00 13.60 ?  124  LEU B HD21 1 
ATOM   7521  H HD22 . LEU B 1 158 ? 12.095  33.005  38.065 1.00 13.60 ?  124  LEU B HD22 1 
ATOM   7522  H HD23 . LEU B 1 158 ? 11.639  31.646  37.382 1.00 13.60 ?  124  LEU B HD23 1 
ATOM   7523  N N    . LYS B 1 159 ? 14.762  31.973  33.384 1.00 10.95 ?  125  LYS B N    1 
ATOM   7524  C CA   . LYS B 1 159 ? 15.277  30.779  32.741 1.00 12.16 ?  125  LYS B CA   1 
ATOM   7525  C C    . LYS B 1 159 ? 16.175  30.038  33.718 1.00 10.63 ?  125  LYS B C    1 
ATOM   7526  O O    . LYS B 1 159 ? 16.754  30.626  34.635 1.00 12.61 ?  125  LYS B O    1 
ATOM   7527  C CB   . LYS B 1 159 ? 16.061  31.151  31.488 1.00 13.03 ?  125  LYS B CB   1 
ATOM   7528  C CG   . LYS B 1 159 ? 15.131  31.499  30.342 1.00 15.90 ?  125  LYS B CG   1 
ATOM   7529  C CD   . LYS B 1 159 ? 15.826  32.175  29.189 1.00 21.27 ?  125  LYS B CD   1 
ATOM   7530  C CE   . LYS B 1 159 ? 14.818  32.860  28.300 1.00 25.49 ?  125  LYS B CE   1 
ATOM   7531  N NZ   . LYS B 1 159 ? 15.492  33.419  27.097 1.00 34.52 ?  125  LYS B NZ   1 
ATOM   7532  H H    . LYS B 1 159 ? 15.374  32.458  33.744 1.00 13.14 ?  125  LYS B H    1 
ATOM   7533  H HA   . LYS B 1 159 ? 14.554  30.184  32.490 1.00 14.59 ?  125  LYS B HA   1 
ATOM   7534  H HB2  . LYS B 1 159 ? 16.619  31.922  31.675 1.00 15.63 ?  125  LYS B HB2  1 
ATOM   7535  H HB3  . LYS B 1 159 ? 16.613  30.400  31.219 1.00 15.63 ?  125  LYS B HB3  1 
ATOM   7536  H HG2  . LYS B 1 159 ? 14.727  30.683  30.007 1.00 19.07 ?  125  LYS B HG2  1 
ATOM   7537  H HG3  . LYS B 1 159 ? 14.442  32.100  30.667 1.00 19.07 ?  125  LYS B HG3  1 
ATOM   7538  H HD2  . LYS B 1 159 ? 16.444  32.842  29.528 1.00 25.53 ?  125  LYS B HD2  1 
ATOM   7539  H HD3  . LYS B 1 159 ? 16.305  31.515  28.664 1.00 25.53 ?  125  LYS B HD3  1 
ATOM   7540  H HE2  . LYS B 1 159 ? 14.150  32.219  28.012 1.00 30.59 ?  125  LYS B HE2  1 
ATOM   7541  H HE3  . LYS B 1 159 ? 14.395  33.585  28.785 1.00 30.59 ?  125  LYS B HE3  1 
ATOM   7542  H HZ1  . LYS B 1 159 ? 14.895  33.820  26.573 1.00 41.43 ?  125  LYS B HZ1  1 
ATOM   7543  H HZ2  . LYS B 1 159 ? 16.107  34.014  27.342 1.00 41.43 ?  125  LYS B HZ2  1 
ATOM   7544  H HZ3  . LYS B 1 159 ? 15.887  32.767  26.639 1.00 41.43 ?  125  LYS B HZ3  1 
ATOM   7545  N N    . ASN B 1 160 ? 16.294  28.732  33.507 1.00 11.72 ?  126  ASN B N    1 
ATOM   7546  C CA   . ASN B 1 160 ? 17.193  27.912  34.303 1.00 13.78 ?  126  ASN B CA   1 
ATOM   7547  C C    . ASN B 1 160 ? 18.614  28.011  33.741 1.00 12.82 ?  126  ASN B C    1 
ATOM   7548  O O    . ASN B 1 160 ? 18.903  28.785  32.824 1.00 11.98 ?  126  ASN B O    1 
ATOM   7549  C CB   . ASN B 1 160 ? 16.692  26.474  34.395 1.00 13.94 ?  126  ASN B CB   1 
ATOM   7550  C CG   . ASN B 1 160 ? 16.737  25.738  33.069 1.00 14.84 ?  126  ASN B CG   1 
ATOM   7551  O OD1  . ASN B 1 160 ? 17.396  26.159  32.113 1.00 13.01 ?  126  ASN B OD1  1 
ATOM   7552  N ND2  . ASN B 1 160 ? 16.041  24.614  33.008 1.00 17.71 ?  126  ASN B ND2  1 
ATOM   7553  H H    . ASN B 1 160 ? 15.862  28.297  32.904 1.00 14.06 ?  126  ASN B H    1 
ATOM   7554  H HA   . ASN B 1 160 ? 17.199  28.271  35.204 1.00 16.53 ?  126  ASN B HA   1 
ATOM   7555  H HB2  . ASN B 1 160 ? 17.247  25.988  35.025 1.00 16.73 ?  126  ASN B HB2  1 
ATOM   7556  H HB3  . ASN B 1 160 ? 15.771  26.481  34.701 1.00 16.73 ?  126  ASN B HB3  1 
ATOM   7557  H HD21 . ASN B 1 160 ? 16.030  24.154  32.281 1.00 21.25 ?  126  ASN B HD21 1 
ATOM   7558  H HD22 . ASN B 1 160 ? 15.600  24.344  33.695 1.00 21.25 ?  126  ASN B HD22 1 
ATOM   7559  N N    . GLN B 1 161 ? 19.500  27.184  34.286 1.00 14.75 ?  127  GLN B N    1 
ATOM   7560  C CA   . GLN B 1 161 ? 20.911  27.268  33.948 1.00 16.41 ?  127  GLN B CA   1 
ATOM   7561  C C    . GLN B 1 161 ? 21.205  26.793  32.535 1.00 15.36 ?  127  GLN B C    1 
ATOM   7562  O O    . GLN B 1 161 ? 22.275  27.104  32.006 1.00 16.31 ?  127  GLN B O    1 
ATOM   7563  C CB   . GLN B 1 161 ? 21.717  26.489  34.988 1.00 19.40 ?  127  GLN B CB   1 
ATOM   7564  C CG   . GLN B 1 161 ? 21.470  26.983  36.427 1.00 36.01 ?  127  GLN B CG   1 
ATOM   7565  C CD   . GLN B 1 161 ? 20.491  26.117  37.224 1.00 34.80 ?  127  GLN B CD   1 
ATOM   7566  O OE1  . GLN B 1 161 ? 19.333  25.886  36.824 1.00 27.44 ?  127  GLN B OE1  1 
ATOM   7567  N NE2  . GLN B 1 161 ? 20.950  25.664  38.390 1.00 31.28 ?  127  GLN B NE2  1 
ATOM   7568  H H    . GLN B 1 161 ? 19.308  26.567  34.853 1.00 17.70 ?  127  GLN B H    1 
ATOM   7569  H HA   . GLN B 1 161 ? 21.204  28.192  33.984 1.00 19.70 ?  127  GLN B HA   1 
ATOM   7570  H HB2  . GLN B 1 161 ? 21.466  25.553  34.944 1.00 23.28 ?  127  GLN B HB2  1 
ATOM   7571  H HB3  . GLN B 1 161 ? 22.662  26.589  34.794 1.00 23.28 ?  127  GLN B HB3  1 
ATOM   7572  H HG2  . GLN B 1 161 ? 22.314  26.987  36.904 1.00 43.22 ?  127  GLN B HG2  1 
ATOM   7573  H HG3  . GLN B 1 161 ? 21.105  27.881  36.389 1.00 43.22 ?  127  GLN B HG3  1 
ATOM   7574  H HE21 . GLN B 1 161 ? 21.747  25.864  38.646 1.00 37.54 ?  127  GLN B HE21 1 
ATOM   7575  H HE22 . GLN B 1 161 ? 20.450  25.171  38.887 1.00 37.54 ?  127  GLN B HE22 1 
ATOM   7576  N N    . ASN B 1 162 ? 20.276  26.094  31.903 1.00 13.83 ?  128  ASN B N    1 
ATOM   7577  C CA   . ASN B 1 162 ? 20.384  25.687  30.513 1.00 14.75 ?  128  ASN B CA   1 
ATOM   7578  C C    . ASN B 1 162 ? 19.680  26.658  29.587 1.00 15.25 ?  128  ASN B C    1 
ATOM   7579  O O    . ASN B 1 162 ? 19.540  26.385  28.392 1.00 14.77 ?  128  ASN B O    1 
ATOM   7580  C CB   . ASN B 1 162 ? 19.869  24.272  30.392 1.00 20.27 ?  128  ASN B CB   1 
ATOM   7581  C CG   . ASN B 1 162 ? 20.592  23.361  31.322 1.00 30.98 ?  128  ASN B CG   1 
ATOM   7582  O OD1  . ASN B 1 162 ? 21.761  23.058  31.108 1.00 23.51 ?  128  ASN B OD1  1 
ATOM   7583  N ND2  . ASN B 1 162 ? 19.948  23.013  32.429 1.00 32.08 ?  128  ASN B ND2  1 
ATOM   7584  H H    . ASN B 1 162 ? 19.545  25.834  32.273 1.00 16.59 ?  128  ASN B H    1 
ATOM   7585  H HA   . ASN B 1 162 ? 21.308  25.673  30.219 1.00 17.69 ?  128  ASN B HA   1 
ATOM   7586  H HB2  . ASN B 1 162 ? 18.925  24.252  30.614 1.00 24.33 ?  128  ASN B HB2  1 
ATOM   7587  H HB3  . ASN B 1 162 ? 20.004  23.956  29.485 1.00 24.33 ?  128  ASN B HB3  1 
ATOM   7588  H HD21 . ASN B 1 162 ? 19.156  23.311  32.578 1.00 38.49 ?  128  ASN B HD21 1 
ATOM   7589  H HD22 . ASN B 1 162 ? 20.324  22.488  32.998 1.00 38.49 ?  128  ASN B HD22 1 
ATOM   7590  N N    . ASN B 1 163 ? 19.272  27.811  30.115 1.00 12.39 ?  129  ASN B N    1 
ATOM   7591  C CA   . ASN B 1 163 ? 18.611  28.856  29.357 1.00 12.80 ?  129  ASN B CA   1 
ATOM   7592  C C    . ASN B 1 163 ? 17.227  28.435  28.853 1.00 11.92 ?  129  ASN B C    1 
ATOM   7593  O O    . ASN B 1 163 ? 16.736  28.997  27.871 1.00 14.33 ?  129  ASN B O    1 
ATOM   7594  C CB   . ASN B 1 163 ? 19.480  29.395  28.223 1.00 15.17 ?  129  ASN B CB   1 
ATOM   7595  C CG   . ASN B 1 163 ? 19.333  30.879  28.069 1.00 18.74 ?  129  ASN B CG   1 
ATOM   7596  O OD1  . ASN B 1 163 ? 19.310  31.610  29.070 1.00 21.70 ?  129  ASN B OD1  1 
ATOM   7597  N ND2  . ASN B 1 163 ? 19.203  31.342  26.836 1.00 21.15 ?  129  ASN B ND2  1 
ATOM   7598  H H    . ASN B 1 163 ? 19.374  28.014  30.944 1.00 14.86 ?  129  ASN B H    1 
ATOM   7599  H HA   . ASN B 1 163 ? 18.463  29.598  29.963 1.00 15.36 ?  129  ASN B HA   1 
ATOM   7600  H HB2  . ASN B 1 163 ? 20.411  29.199  28.413 1.00 18.20 ?  129  ASN B HB2  1 
ATOM   7601  H HB3  . ASN B 1 163 ? 19.216  28.975  27.390 1.00 18.20 ?  129  ASN B HB3  1 
ATOM   7602  H HD21 . ASN B 1 163 ? 19.205  30.799  26.170 1.00 25.38 ?  129  ASN B HD21 1 
ATOM   7603  H HD22 . ASN B 1 163 ? 19.116  32.187  26.701 1.00 25.38 ?  129  ASN B HD22 1 
ATOM   7604  N N    . GLU B 1 164 ? 16.591  27.508  29.565 1.00 11.98 ?  130  GLU B N    1 
ATOM   7605  C CA   . GLU B 1 164 ? 15.213  27.105  29.293 1.00 12.68 ?  130  GLU B CA   1 
ATOM   7606  C C    . GLU B 1 164 ? 14.265  27.898  30.185 1.00 11.11 ?  130  GLU B C    1 
ATOM   7607  O O    . GLU B 1 164 ? 14.511  28.058  31.385 1.00 11.82 ?  130  GLU B O    1 
ATOM   7608  C CB   . GLU B 1 164 ? 15.002  25.617  29.591 1.00 13.83 ?  130  GLU B CB   1 
ATOM   7609  C CG   . GLU B 1 164 ? 16.016  24.662  28.971 1.00 16.98 ?  130  GLU B CG   1 
ATOM   7610  C CD   . GLU B 1 164 ? 15.803  23.222  29.421 1.00 27.26 ?  130  GLU B CD   1 
ATOM   7611  O OE1  . GLU B 1 164 ? 16.360  22.846  30.484 1.00 26.22 ?  130  GLU B OE1  1 
ATOM   7612  O OE2  . GLU B 1 164 ? 15.126  22.458  28.696 1.00 36.21 ?  130  GLU B OE2  1 
ATOM   7613  H H    . GLU B 1 164 ? 16.944  27.087  30.227 1.00 14.38 ?  130  GLU B H    1 
ATOM   7614  H HA   . GLU B 1 164 ? 15.018  27.272  28.358 1.00 15.22 ?  130  GLU B HA   1 
ATOM   7615  H HB2  . GLU B 1 164 ? 15.040  25.492  30.552 1.00 16.60 ?  130  GLU B HB2  1 
ATOM   7616  H HB3  . GLU B 1 164 ? 14.127  25.363  29.258 1.00 16.60 ?  130  GLU B HB3  1 
ATOM   7617  H HG2  . GLU B 1 164 ? 15.932  24.691  28.005 1.00 20.38 ?  130  GLU B HG2  1 
ATOM   7618  H HG3  . GLU B 1 164 ? 16.910  24.932  29.234 1.00 20.38 ?  130  GLU B HG3  1 
ATOM   7619  N N    . LEU B 1 165 ? 13.170  28.355  29.589 1.00 12.21 ?  131  LEU B N    1 
ATOM   7620  C CA   . LEU B 1 165 ? 12.090  28.935  30.380 1.00 11.74 ?  131  LEU B CA   1 
ATOM   7621  C C    . LEU B 1 165 ? 11.577  27.919  31.392 1.00 12.95 ?  131  LEU B C    1 
ATOM   7622  O O    . LEU B 1 165 ? 11.501  26.719  31.122 1.00 12.95 ?  131  LEU B O    1 
ATOM   7623  C CB   . LEU B 1 165 ? 10.944  29.336  29.458 1.00 14.09 ?  131  LEU B CB   1 
ATOM   7624  C CG   . LEU B 1 165 ? 11.192  30.570  28.607 1.00 13.20 ?  131  LEU B CG   1 
ATOM   7625  C CD1  . LEU B 1 165 ? 10.125  30.665  27.533 1.00 17.59 ?  131  LEU B CD1  1 
ATOM   7626  C CD2  . LEU B 1 165 ? 11.234  31.833  29.460 1.00 14.23 ?  131  LEU B CD2  1 
ATOM   7627  H H    . LEU B 1 165 ? 13.029  28.343  28.741 1.00 14.65 ?  131  LEU B H    1 
ATOM   7628  H HA   . LEU B 1 165 ? 12.415  29.718  30.851 1.00 14.09 ?  131  LEU B HA   1 
ATOM   7629  H HB2  . LEU B 1 165 ? 10.767  28.599  28.853 1.00 16.90 ?  131  LEU B HB2  1 
ATOM   7630  H HB3  . LEU B 1 165 ? 10.162  29.514  30.003 1.00 16.90 ?  131  LEU B HB3  1 
ATOM   7631  H HG   . LEU B 1 165 ? 12.059  30.497  28.177 1.00 15.84 ?  131  LEU B HG   1 
ATOM   7632  H HD11 . LEU B 1 165 ? 10.199  31.525  27.090 1.00 21.11 ?  131  LEU B HD11 1 
ATOM   7633  H HD12 . LEU B 1 165 ? 10.257  29.949  26.892 1.00 21.11 ?  131  LEU B HD12 1 
ATOM   7634  H HD13 . LEU B 1 165 ? 9.252   30.581  27.948 1.00 21.11 ?  131  LEU B HD13 1 
ATOM   7635  H HD21 . LEU B 1 165 ? 11.511  32.579  28.906 1.00 17.07 ?  131  LEU B HD21 1 
ATOM   7636  H HD22 . LEU B 1 165 ? 10.350  31.999  29.822 1.00 17.07 ?  131  LEU B HD22 1 
ATOM   7637  H HD23 . LEU B 1 165 ? 11.868  31.705  30.183 1.00 17.07 ?  131  LEU B HD23 1 
ATOM   7638  N N    . VAL B 1 166 ? 11.227  28.404  32.571 1.00 10.60 ?  132  VAL B N    1 
ATOM   7639  C CA   . VAL B 1 166 ? 10.535  27.608  33.577 1.00 11.35 ?  132  VAL B CA   1 
ATOM   7640  C C    . VAL B 1 166 ? 9.109   28.136  33.738 1.00 9.33  ?  132  VAL B C    1 
ATOM   7641  O O    . VAL B 1 166 ? 8.817   29.291  33.437 1.00 10.11 ?  132  VAL B O    1 
ATOM   7642  C CB   . VAL B 1 166 ? 11.281  27.562  34.919 1.00 9.76  ?  132  VAL B CB   1 
ATOM   7643  C CG1  . VAL B 1 166 ? 12.651  26.894  34.732 1.00 13.86 ?  132  VAL B CG1  1 
ATOM   7644  C CG2  . VAL B 1 166 ? 11.433  28.948  35.523 1.00 10.71 ?  132  VAL B CG2  1 
ATOM   7645  H H    . VAL B 1 166 ? 11.381  29.212  32.821 1.00 12.72 ?  132  VAL B H    1 
ATOM   7646  H HA   . VAL B 1 166 ? 10.474  26.694  33.258 1.00 13.62 ?  132  VAL B HA   1 
ATOM   7647  H HB   . VAL B 1 166 ? 10.759  27.036  35.544 1.00 11.71 ?  132  VAL B HB   1 
ATOM   7648  H HG11 . VAL B 1 166 ? 13.182  27.033  35.532 1.00 16.63 ?  132  VAL B HG11 1 
ATOM   7649  H HG12 . VAL B 1 166 ? 12.522  25.944  34.583 1.00 16.63 ?  132  VAL B HG12 1 
ATOM   7650  H HG13 . VAL B 1 166 ? 13.095  27.292  33.967 1.00 16.63 ?  132  VAL B HG13 1 
ATOM   7651  H HG21 . VAL B 1 166 ? 11.863  28.869  36.389 1.00 12.85 ?  132  VAL B HG21 1 
ATOM   7652  H HG22 . VAL B 1 166 ? 11.976  29.493  34.933 1.00 12.85 ?  132  VAL B HG22 1 
ATOM   7653  H HG23 . VAL B 1 166 ? 10.554  29.346  35.625 1.00 12.85 ?  132  VAL B HG23 1 
ATOM   7654  N N    . TYR B 1 167 ? 8.221   27.272  34.221 1.00 9.24  ?  133  TYR B N    1 
ATOM   7655  C CA   . TYR B 1 167 ? 6.797   27.540  34.149 1.00 9.07  ?  133  TYR B CA   1 
ATOM   7656  C C    . TYR B 1 167 ? 6.055   27.153  35.416 1.00 8.39  ?  133  TYR B C    1 
ATOM   7657  O O    . TYR B 1 167 ? 6.517   26.362  36.241 1.00 10.30 ?  133  TYR B O    1 
ATOM   7658  C CB   . TYR B 1 167 ? 6.176   26.716  33.025 1.00 9.84  ?  133  TYR B CB   1 
ATOM   7659  C CG   . TYR B 1 167 ? 6.729   26.994  31.674 1.00 10.71 ?  133  TYR B CG   1 
ATOM   7660  C CD1  . TYR B 1 167 ? 6.352   28.107  30.956 1.00 12.24 ?  133  TYR B CD1  1 
ATOM   7661  C CD2  . TYR B 1 167 ? 7.634   26.102  31.094 1.00 15.12 ?  133  TYR B CD2  1 
ATOM   7662  C CE1  . TYR B 1 167 ? 6.882   28.345  29.677 1.00 14.11 ?  133  TYR B CE1  1 
ATOM   7663  C CE2  . TYR B 1 167 ? 8.143   26.321  29.853 1.00 18.42 ?  133  TYR B CE2  1 
ATOM   7664  C CZ   . TYR B 1 167 ? 7.775   27.432  29.155 1.00 14.95 ?  133  TYR B CZ   1 
ATOM   7665  O OH   . TYR B 1 167 ? 8.302   27.597  27.889 1.00 25.41 ?  133  TYR B OH   1 
ATOM   7666  H H    . TYR B 1 167 ? 8.423   26.524  34.595 1.00 11.09 ?  133  TYR B H    1 
ATOM   7667  H HA   . TYR B 1 167 ? 6.696   28.497  34.029 1.00 10.88 ?  133  TYR B HA   1 
ATOM   7668  H HB2  . TYR B 1 167 ? 6.324   25.776  33.214 1.00 11.81 ?  133  TYR B HB2  1 
ATOM   7669  H HB3  . TYR B 1 167 ? 5.225   26.903  32.995 1.00 11.81 ?  133  TYR B HB3  1 
ATOM   7670  H HD1  . TYR B 1 167 ? 5.742   28.707  31.321 1.00 14.69 ?  133  TYR B HD1  1 
ATOM   7671  H HD2  . TYR B 1 167 ? 7.893   25.344  31.565 1.00 18.14 ?  133  TYR B HD2  1 
ATOM   7672  H HE1  . TYR B 1 167 ? 6.636   29.100  29.193 1.00 16.93 ?  133  TYR B HE1  1 
ATOM   7673  H HE2  . TYR B 1 167 ? 8.742   25.714  29.481 1.00 22.10 ?  133  TYR B HE2  1 
ATOM   7674  H HH   . TYR B 1 167 ? 8.745   26.917  27.671 1.00 30.49 ?  133  TYR B HH   1 
ATOM   7675  N N    . MET B 1 168 ? 4.863   27.726  35.536 1.00 7.86  ?  134  MET B N    1 
ATOM   7676  C CA   . MET B 1 168 ? 3.839   27.303  36.479 1.00 8.68  ?  134  MET B CA   1 
ATOM   7677  C C    . MET B 1 168 ? 3.367   25.897  36.134 1.00 8.76  ?  134  MET B C    1 
ATOM   7678  O O    . MET B 1 168 ? 3.764   25.337  35.107 1.00 8.60  ?  134  MET B O    1 
ATOM   7679  C CB   . MET B 1 168 ? 2.679   28.290  36.366 1.00 7.96  ?  134  MET B CB   1 
ATOM   7680  C CG   . MET B 1 168 ? 2.986   29.573  37.101 1.00 8.88  ?  134  MET B CG   1 
ATOM   7681  S SD   . MET B 1 168 ? 3.134   29.470  38.867 1.00 9.26  ?  134  MET B SD   1 
ATOM   7682  C CE   . MET B 1 168 ? 1.449   29.115  39.358 1.00 9.78  ?  134  MET B CE   1 
ATOM   7683  H H    . MET B 1 168 ? 4.611   28.395  35.058 1.00 9.43  ?  134  MET B H    1 
ATOM   7684  H HA   . MET B 1 168 ? 4.184   27.293  37.386 1.00 10.42 ?  134  MET B HA   1 
ATOM   7685  H HB2  . MET B 1 168 ? 2.524   28.499  35.431 1.00 9.55  ?  134  MET B HB2  1 
ATOM   7686  H HB3  . MET B 1 168 ? 1.882   27.896  36.754 1.00 9.55  ?  134  MET B HB3  1 
ATOM   7687  H HG2  . MET B 1 168 ? 3.829   29.916  36.766 1.00 10.66 ?  134  MET B HG2  1 
ATOM   7688  H HG3  . MET B 1 168 ? 2.273   30.204  36.913 1.00 10.66 ?  134  MET B HG3  1 
ATOM   7689  H HE1  . MET B 1 168 ? 1.417   29.006  40.321 1.00 11.73 ?  134  MET B HE1  1 
ATOM   7690  H HE2  . MET B 1 168 ? 0.880   29.853  39.089 1.00 11.73 ?  134  MET B HE2  1 
ATOM   7691  H HE3  . MET B 1 168 ? 1.159   28.298  38.923 1.00 11.73 ?  134  MET B HE3  1 
ATOM   7692  N N    . PRO B 1 169 ? 2.533   25.295  36.978 1.00 8.13  ?  135  PRO B N    1 
ATOM   7693  C CA   . PRO B 1 169 ? 2.094   23.921  36.702 1.00 9.03  ?  135  PRO B CA   1 
ATOM   7694  C C    . PRO B 1 169 ? 1.372   23.746  35.394 1.00 8.44  ?  135  PRO B C    1 
ATOM   7695  O O    . PRO B 1 169 ? 1.314   22.602  34.904 1.00 9.83  ?  135  PRO B O    1 
ATOM   7696  C CB   . PRO B 1 169 ? 1.197   23.594  37.904 1.00 9.19  ?  135  PRO B CB   1 
ATOM   7697  C CG   . PRO B 1 169 ? 1.827   24.402  39.031 1.00 8.67  ?  135  PRO B CG   1 
ATOM   7698  C CD   . PRO B 1 169 ? 2.173   25.718  38.351 1.00 8.50  ?  135  PRO B CD   1 
ATOM   7699  H HA   . PRO B 1 169 ? 2.860   23.326  36.705 1.00 10.83 ?  135  PRO B HA   1 
ATOM   7700  H HB2  . PRO B 1 169 ? 0.285   23.877  37.732 1.00 11.03 ?  135  PRO B HB2  1 
ATOM   7701  H HB3  . PRO B 1 169 ? 1.219   22.643  38.094 1.00 11.03 ?  135  PRO B HB3  1 
ATOM   7702  H HG2  . PRO B 1 169 ? 1.192   24.531  39.752 1.00 10.41 ?  135  PRO B HG2  1 
ATOM   7703  H HG3  . PRO B 1 169 ? 2.621   23.956  39.364 1.00 10.41 ?  135  PRO B HG3  1 
ATOM   7704  H HD2  . PRO B 1 169 ? 1.408   26.314  38.341 1.00 10.19 ?  135  PRO B HD2  1 
ATOM   7705  H HD3  . PRO B 1 169 ? 2.924   26.148  38.790 1.00 10.19 ?  135  PRO B HD3  1 
ATOM   7706  N N    . ASN B 1 170 ? 0.790   24.795  34.811 1.00 8.05  ?  136  ASN B N    1 
ATOM   7707  C CA   . ASN B 1 170 ? 0.145   24.666  33.513 1.00 8.34  ?  136  ASN B CA   1 
ATOM   7708  C C    . ASN B 1 170 ? 1.141   24.461  32.386 1.00 8.54  ?  136  ASN B C    1 
ATOM   7709  O O    . ASN B 1 170 ? 0.718   24.182  31.256 1.00 9.20  ?  136  ASN B O    1 
ATOM   7710  C CB   . ASN B 1 170 ? -0.795  25.833  33.225 1.00 9.11  ?  136  ASN B CB   1 
ATOM   7711  C CG   . ASN B 1 170 ? -0.095  27.159  33.155 1.00 8.69  ?  136  ASN B CG   1 
ATOM   7712  O OD1  . ASN B 1 170 ? 1.116   27.260  32.960 1.00 8.61  ?  136  ASN B OD1  1 
ATOM   7713  N ND2  . ASN B 1 170 ? -0.871  28.208  33.292 1.00 10.02 ?  136  ASN B ND2  1 
ATOM   7714  H H    . ASN B 1 170 ? 0.757   25.586  35.148 1.00 9.66  ?  136  ASN B H    1 
ATOM   7715  H HA   . ASN B 1 170 ? -0.428  23.884  33.538 1.00 10.00 ?  136  ASN B HA   1 
ATOM   7716  H HB2  . ASN B 1 170 ? -1.230  25.682  32.372 1.00 10.93 ?  136  ASN B HB2  1 
ATOM   7717  H HB3  . ASN B 1 170 ? -1.457  25.884  33.932 1.00 10.93 ?  136  ASN B HB3  1 
ATOM   7718  H HD21 . ASN B 1 170 ? -0.534  28.998  33.262 1.00 12.02 ?  136  ASN B HD21 1 
ATOM   7719  H HD22 . ASN B 1 170 ? -1.716  28.105  33.411 1.00 12.02 ?  136  ASN B HD22 1 
ATOM   7720  N N    . GLY B 1 171 ? 2.436   24.625  32.657 1.00 8.75  ?  137  GLY B N    1 
ATOM   7721  C CA   . GLY B 1 171 ? 3.480   24.385  31.674 1.00 8.65  ?  137  GLY B CA   1 
ATOM   7722  C C    . GLY B 1 171 ? 3.607   25.452  30.621 1.00 9.86  ?  137  GLY B C    1 
ATOM   7723  O O    . GLY B 1 171 ? 4.366   25.273  29.659 1.00 9.83  ?  137  GLY B O    1 
ATOM   7724  H H    . GLY B 1 171 ? 2.738   24.882  33.420 1.00 10.50 ?  137  GLY B H    1 
ATOM   7725  H HA2  . GLY B 1 171 ? 4.332   24.319  32.134 1.00 10.38 ?  137  GLY B HA2  1 
ATOM   7726  H HA3  . GLY B 1 171 ? 3.298   23.544  31.225 1.00 10.38 ?  137  GLY B HA3  1 
ATOM   7727  N N    A SER B 1 172 ? 2.900   26.565  30.770 0.66 9.51  ?  138  SER B N    1 
ATOM   7728  N N    B SER B 1 172 ? 2.906   26.570  30.780 0.34 9.55  ?  138  SER B N    1 
ATOM   7729  C CA   A SER B 1 172 ? 2.912   27.615  29.757 0.66 9.45  ?  138  SER B CA   1 
ATOM   7730  C CA   B SER B 1 172 ? 2.891   27.611  29.760 0.34 9.53  ?  138  SER B CA   1 
ATOM   7731  C C    A SER B 1 172 ? 3.022   29.024  30.322 0.66 10.42 ?  138  SER B C    1 
ATOM   7732  C C    B SER B 1 172 ? 2.992   29.026  30.310 0.34 10.43 ?  138  SER B C    1 
ATOM   7733  O O    A SER B 1 172 ? 3.510   29.901  29.604 0.66 11.57 ?  138  SER B O    1 
ATOM   7734  O O    B SER B 1 172 ? 3.421   29.913  29.566 0.34 11.56 ?  138  SER B O    1 
ATOM   7735  C CB   A SER B 1 172 ? 1.668   27.504  28.867 0.66 11.44 ?  138  SER B CB   1 
ATOM   7736  C CB   B SER B 1 172 ? 1.624   27.483  28.905 0.34 11.41 ?  138  SER B CB   1 
ATOM   7737  O OG   A SER B 1 172 ? 0.484   27.638  29.633 0.66 16.44 ?  138  SER B OG   1 
ATOM   7738  O OG   B SER B 1 172 ? 1.621   28.423  27.851 0.34 9.08  ?  138  SER B OG   1 
ATOM   7739  H H    A SER B 1 172 ? 2.403   26.738  31.450 0.66 11.41 ?  138  SER B H    1 
ATOM   7740  H H    B SER B 1 172 ? 2.430   26.750  31.473 0.34 11.47 ?  138  SER B H    1 
ATOM   7741  H HA   A SER B 1 172 ? 3.683   27.491  29.181 0.66 11.34 ?  138  SER B HA   1 
ATOM   7742  H HA   B SER B 1 172 ? 3.652   27.490  29.171 0.34 11.44 ?  138  SER B HA   1 
ATOM   7743  H HB2  A SER B 1 172 ? 1.694   28.208  28.200 0.66 13.73 ?  138  SER B HB2  1 
ATOM   7744  H HB2  B SER B 1 172 ? 1.588   26.589  28.529 0.34 13.70 ?  138  SER B HB2  1 
ATOM   7745  H HB3  A SER B 1 172 ? 1.667   26.636  28.434 0.66 13.73 ?  138  SER B HB3  1 
ATOM   7746  H HB3  B SER B 1 172 ? 0.849   27.638  29.467 0.34 13.70 ?  138  SER B HB3  1 
ATOM   7747  H HG   A SER B 1 172 ? -0.189  27.503  29.149 0.66 19.72 ?  138  SER B HG   1 
ATOM   7748  H HG   B SER B 1 172 ? 1.147   28.142  27.217 0.34 10.89 ?  138  SER B HG   1 
ATOM   7749  N N    . THR B 1 173 ? 2.627   29.284  31.565 1.00 8.96  ?  139  THR B N    1 
ATOM   7750  C CA   . THR B 1 173 ? 2.771   30.619  32.147 1.00 9.00  ?  139  THR B CA   1 
ATOM   7751  C C    . THR B 1 173 ? 4.154   30.744  32.765 1.00 8.69  ?  139  THR B C    1 
ATOM   7752  O O    . THR B 1 173 ? 4.485   29.963  33.661 1.00 9.41  ?  139  THR B O    1 
ATOM   7753  C CB   . THR B 1 173 ? 1.732   30.833  33.243 1.00 7.77  ?  139  THR B CB   1 
ATOM   7754  O OG1  . THR B 1 173 ? 0.419   30.668  32.679 1.00 10.32 ?  139  THR B OG1  1 
ATOM   7755  C CG2  . THR B 1 173 ? 1.864   32.223  33.863 1.00 8.93  ?  139  THR B CG2  1 
ATOM   7756  H H    . THR B 1 173 ? 2.272   28.706  32.094 1.00 10.76 ?  139  THR B H    1 
ATOM   7757  H HA   . THR B 1 173 ? 2.658   31.290  31.456 1.00 10.80 ?  139  THR B HA   1 
ATOM   7758  H HB   . THR B 1 173 ? 1.867   30.187  33.953 1.00 9.32  ?  139  THR B HB   1 
ATOM   7759  H HG1  . THR B 1 173 ? 0.316   31.192  32.031 1.00 12.38 ?  139  THR B HG1  1 
ATOM   7760  H HG21 . THR B 1 173 ? 1.126   32.387  34.470 1.00 10.71 ?  139  THR B HG21 1 
ATOM   7761  H HG22 . THR B 1 173 ? 2.698   32.289  34.355 1.00 10.71 ?  139  THR B HG22 1 
ATOM   7762  H HG23 . THR B 1 173 ? 1.855   32.899  33.167 1.00 10.71 ?  139  THR B HG23 1 
ATOM   7763  N N    . PRO B 1 174 ? 4.984   31.695  32.307 1.00 7.84  ?  140  PRO B N    1 
ATOM   7764  C CA   . PRO B 1 174 ? 6.359   31.834  32.795 1.00 8.08  ?  140  PRO B CA   1 
ATOM   7765  C C    . PRO B 1 174 ? 6.434   32.890  33.890 1.00 8.40  ?  140  PRO B C    1 
ATOM   7766  O O    . PRO B 1 174 ? 5.389   33.374  34.375 1.00 8.68  ?  140  PRO B O    1 
ATOM   7767  C CB   . PRO B 1 174 ? 7.095   32.297  31.531 1.00 9.52  ?  140  PRO B CB   1 
ATOM   7768  C CG   . PRO B 1 174 ? 6.104   33.199  30.865 1.00 9.05  ?  140  PRO B CG   1 
ATOM   7769  C CD   . PRO B 1 174 ? 4.728   32.598  31.176 1.00 9.12  ?  140  PRO B CD   1 
ATOM   7770  H HA   . PRO B 1 174 ? 6.729   30.994  33.108 1.00 9.70  ?  140  PRO B HA   1 
ATOM   7771  H HB2  . PRO B 1 174 ? 7.904   32.776  31.769 1.00 11.43 ?  140  PRO B HB2  1 
ATOM   7772  H HB3  . PRO B 1 174 ? 7.312   31.536  30.970 1.00 11.43 ?  140  PRO B HB3  1 
ATOM   7773  H HG2  . PRO B 1 174 ? 6.179   34.095  31.229 1.00 10.86 ?  140  PRO B HG2  1 
ATOM   7774  H HG3  . PRO B 1 174 ? 6.265   33.215  29.909 1.00 10.86 ?  140  PRO B HG3  1 
ATOM   7775  H HD2  . PRO B 1 174 ? 4.100   33.293  31.428 1.00 10.95 ?  140  PRO B HD2  1 
ATOM   7776  H HD3  . PRO B 1 174 ? 4.389   32.105  30.413 1.00 10.95 ?  140  PRO B HD3  1 
ATOM   7777  N N    . PHE B 1 175 ? 7.655   33.239  34.298 1.00 8.45  ?  141  PHE B N    1 
ATOM   7778  C CA   . PHE B 1 175 ? 7.899   34.144  35.412 1.00 9.74  ?  141  PHE B CA   1 
ATOM   7779  C C    . PHE B 1 175 ? 8.767   35.306  34.954 1.00 11.37 ?  141  PHE B C    1 
ATOM   7780  O O    . PHE B 1 175 ? 9.608   35.162  34.058 1.00 10.26 ?  141  PHE B O    1 
ATOM   7781  C CB   . PHE B 1 175 ? 8.642   33.452  36.582 1.00 9.51  ?  141  PHE B CB   1 
ATOM   7782  C CG   . PHE B 1 175 ? 7.960   32.223  37.104 1.00 8.82  ?  141  PHE B CG   1 
ATOM   7783  C CD1  . PHE B 1 175 ? 8.242   30.981  36.562 1.00 9.05  ?  141  PHE B CD1  1 
ATOM   7784  C CD2  . PHE B 1 175 ? 7.028   32.295  38.140 1.00 8.30  ?  141  PHE B CD2  1 
ATOM   7785  C CE1  . PHE B 1 175 ? 7.607   29.838  37.032 1.00 9.49  ?  141  PHE B CE1  1 
ATOM   7786  C CE2  . PHE B 1 175 ? 6.399   31.146  38.612 1.00 8.65  ?  141  PHE B CE2  1 
ATOM   7787  C CZ   . PHE B 1 175 ? 6.701   29.914  38.069 1.00 8.86  ?  141  PHE B CZ   1 
ATOM   7788  H H    . PHE B 1 175 ? 8.379   32.953  33.931 1.00 10.14 ?  141  PHE B H    1 
ATOM   7789  H HA   . PHE B 1 175 ? 7.040   34.467  35.727 1.00 11.69 ?  141  PHE B HA   1 
ATOM   7790  H HB2  . PHE B 1 175 ? 9.525   33.190  36.277 1.00 11.42 ?  141  PHE B HB2  1 
ATOM   7791  H HB3  . PHE B 1 175 ? 8.718   34.080  37.317 1.00 11.42 ?  141  PHE B HB3  1 
ATOM   7792  H HD1  . PHE B 1 175 ? 8.864   30.910  35.874 1.00 10.86 ?  141  PHE B HD1  1 
ATOM   7793  H HD2  . PHE B 1 175 ? 6.825   33.119  38.520 1.00 9.96  ?  141  PHE B HD2  1 
ATOM   7794  H HE1  . PHE B 1 175 ? 7.795   29.014  36.644 1.00 11.39 ?  141  PHE B HE1  1 
ATOM   7795  H HE2  . PHE B 1 175 ? 5.772   31.210  39.297 1.00 10.38 ?  141  PHE B HE2  1 
ATOM   7796  H HZ   . PHE B 1 175 ? 6.297   29.143  38.398 1.00 10.63 ?  141  PHE B HZ   1 
ATOM   7797  N N    . PHE B 1 176 ? 8.570   36.464  35.579 1.00 9.88  ?  142  PHE B N    1 
ATOM   7798  C CA   . PHE B 1 176 ? 9.507   37.571  35.426 1.00 10.21 ?  142  PHE B CA   1 
ATOM   7799  C C    . PHE B 1 176 ? 10.810  37.238  36.139 1.00 9.70  ?  142  PHE B C    1 
ATOM   7800  O O    . PHE B 1 176 ? 10.798  36.786  37.286 1.00 12.34 ?  142  PHE B O    1 
ATOM   7801  C CB   . PHE B 1 176 ? 8.944   38.835  36.084 1.00 10.10 ?  142  PHE B CB   1 
ATOM   7802  C CG   . PHE B 1 176 ? 7.616   39.287  35.551 1.00 11.06 ?  142  PHE B CG   1 
ATOM   7803  C CD1  . PHE B 1 176 ? 7.472   39.642  34.237 1.00 12.50 ?  142  PHE B CD1  1 
ATOM   7804  C CD2  . PHE B 1 176 ? 6.530   39.394  36.396 1.00 10.13 ?  142  PHE B CD2  1 
ATOM   7805  C CE1  . PHE B 1 176 ? 6.242   40.088  33.754 1.00 15.50 ?  142  PHE B CE1  1 
ATOM   7806  C CE2  . PHE B 1 176 ? 5.309   39.828  35.918 1.00 11.52 ?  142  PHE B CE2  1 
ATOM   7807  C CZ   . PHE B 1 176 ? 5.173   40.171  34.622 1.00 12.01 ?  142  PHE B CZ   1 
ATOM   7808  H H    . PHE B 1 176 ? 7.903   36.634  36.095 1.00 11.85 ?  142  PHE B H    1 
ATOM   7809  H HA   . PHE B 1 176 ? 9.660   37.729  34.481 1.00 12.25 ?  142  PHE B HA   1 
ATOM   7810  H HB2  . PHE B 1 176 ? 8.835   38.665  37.033 1.00 12.11 ?  142  PHE B HB2  1 
ATOM   7811  H HB3  . PHE B 1 176 ? 9.575   39.560  35.948 1.00 12.11 ?  142  PHE B HB3  1 
ATOM   7812  H HD1  . PHE B 1 176 ? 8.200   39.585  33.662 1.00 14.99 ?  142  PHE B HD1  1 
ATOM   7813  H HD2  . PHE B 1 176 ? 6.621   39.172  37.295 1.00 12.16 ?  142  PHE B HD2  1 
ATOM   7814  H HE1  . PHE B 1 176 ? 6.144   40.326  32.860 1.00 18.61 ?  142  PHE B HE1  1 
ATOM   7815  H HE2  . PHE B 1 176 ? 4.580   39.883  36.492 1.00 13.82 ?  142  PHE B HE2  1 
ATOM   7816  H HZ   . PHE B 1 176 ? 4.349   40.466  34.309 1.00 14.41 ?  142  PHE B HZ   1 
ATOM   7817  N N    . ASP B 1 177 ? 11.944  37.509  35.476 1.00 10.41 ?  143  ASP B N    1 
ATOM   7818  C CA   . ASP B 1 177 ? 13.239  37.417  36.148 1.00 11.47 ?  143  ASP B CA   1 
ATOM   7819  C C    . ASP B 1 177 ? 13.490  38.740  36.850 1.00 10.60 ?  143  ASP B C    1 
ATOM   7820  O O    . ASP B 1 177 ? 14.128  39.649  36.306 1.00 11.48 ?  143  ASP B O    1 
ATOM   7821  C CB   . ASP B 1 177 ? 14.378  37.088  35.202 1.00 13.81 ?  143  ASP B CB   1 
ATOM   7822  C CG   . ASP B 1 177 ? 15.676  36.861  35.953 1.00 12.24 ?  143  ASP B CG   1 
ATOM   7823  O OD1  . ASP B 1 177 ? 15.729  37.135  37.157 1.00 12.89 ?  143  ASP B OD1  1 
ATOM   7824  O OD2  . ASP B 1 177 ? 16.639  36.353  35.331 1.00 16.59 ?  143  ASP B OD2  1 
ATOM   7825  H H    . ASP B 1 177 ? 11.983  37.743  34.649 1.00 12.49 ?  143  ASP B H    1 
ATOM   7826  H HA   . ASP B 1 177 ? 13.182  36.697  36.796 1.00 13.76 ?  143  ASP B HA   1 
ATOM   7827  H HB2  . ASP B 1 177 ? 14.163  36.280  34.711 1.00 16.57 ?  143  ASP B HB2  1 
ATOM   7828  H HB3  . ASP B 1 177 ? 14.506  37.826  34.586 1.00 16.57 ?  143  ASP B HB3  1 
ATOM   7829  N N    . ILE B 1 178 ? 13.008  38.839  38.087 1.00 9.84  ?  144  ILE B N    1 
ATOM   7830  C CA   . ILE B 1 178 ? 13.120  40.095  38.823 1.00 10.45 ?  144  ILE B CA   1 
ATOM   7831  C C    . ILE B 1 178 ? 14.526  40.350  39.327 1.00 13.27 ?  144  ILE B C    1 
ATOM   7832  O O    . ILE B 1 178 ? 14.763  41.386  39.955 1.00 12.32 ?  144  ILE B O    1 
ATOM   7833  C CB   . ILE B 1 178 ? 12.096  40.183  39.970 1.00 10.89 ?  144  ILE B CB   1 
ATOM   7834  C CG1  . ILE B 1 178 ? 12.308  39.081  41.002 1.00 11.89 ?  144  ILE B CG1  1 
ATOM   7835  C CG2  . ILE B 1 178 ? 10.668  40.100  39.400 1.00 11.91 ?  144  ILE B CG2  1 
ATOM   7836  C CD1  . ILE B 1 178 ? 11.522  39.296  42.272 1.00 11.37 ?  144  ILE B CD1  1 
ATOM   7837  H H    . ILE B 1 178 ? 12.619  38.203  38.515 1.00 11.80 ?  144  ILE B H    1 
ATOM   7838  H HA   . ILE B 1 178 ? 12.904  40.818  38.212 1.00 12.54 ?  144  ILE B HA   1 
ATOM   7839  H HB   . ILE B 1 178 ? 12.225  41.035  40.415 1.00 13.07 ?  144  ILE B HB   1 
ATOM   7840  H HG12 . ILE B 1 178 ? 12.030  38.234  40.620 1.00 14.27 ?  144  ILE B HG12 1 
ATOM   7841  H HG13 . ILE B 1 178 ? 13.248  39.047  41.236 1.00 14.27 ?  144  ILE B HG13 1 
ATOM   7842  H HG21 . ILE B 1 178 ? 10.032  40.242  40.119 1.00 14.29 ?  144  ILE B HG21 1 
ATOM   7843  H HG22 . ILE B 1 178 ? 10.558  40.783  38.721 1.00 14.29 ?  144  ILE B HG22 1 
ATOM   7844  H HG23 . ILE B 1 178 ? 10.534  39.222  39.010 1.00 14.29 ?  144  ILE B HG23 1 
ATOM   7845  H HD11 . ILE B 1 178 ? 11.758  38.604  42.910 1.00 13.64 ?  144  ILE B HD11 1 
ATOM   7846  H HD12 . ILE B 1 178 ? 11.740  40.169  42.634 1.00 13.64 ?  144  ILE B HD12 1 
ATOM   7847  H HD13 . ILE B 1 178 ? 10.575  39.250  42.069 1.00 13.64 ?  144  ILE B HD13 1 
ATOM   7848  N N    . THR B 1 179 ? 15.471  39.440  39.081 1.00 11.81 ?  145  THR B N    1 
ATOM   7849  C CA   . THR B 1 179 ? 16.862  39.756  39.403 1.00 13.04 ?  145  THR B CA   1 
ATOM   7850  C C    . THR B 1 179 ? 17.447  40.783  38.452 1.00 14.23 ?  145  THR B C    1 
ATOM   7851  O O    . THR B 1 179 ? 18.485  41.374  38.777 1.00 14.39 ?  145  THR B O    1 
ATOM   7852  C CB   . THR B 1 179 ? 17.779  38.516  39.397 1.00 14.86 ?  145  THR B CB   1 
ATOM   7853  O OG1  . THR B 1 179 ? 18.043  38.097  38.052 1.00 13.48 ?  145  THR B OG1  1 
ATOM   7854  C CG2  . THR B 1 179 ? 17.207  37.395  40.238 1.00 14.34 ?  145  THR B CG2  1 
ATOM   7855  H H    . THR B 1 179 ? 15.338  38.661  38.742 1.00 14.17 ?  145  THR B H    1 
ATOM   7856  H HA   . THR B 1 179 ? 16.858  40.102  40.309 1.00 15.64 ?  145  THR B HA   1 
ATOM   7857  H HB   . THR B 1 179 ? 18.629  38.747  39.802 1.00 17.83 ?  145  THR B HB   1 
ATOM   7858  H HG1  . THR B 1 179 ? 17.323  37.911  37.662 1.00 16.18 ?  145  THR B HG1  1 
ATOM   7859  H HG21 . THR B 1 179 ? 17.812  36.637  40.236 1.00 17.21 ?  145  THR B HG21 1 
ATOM   7860  H HG22 . THR B 1 179 ? 17.083  37.697  41.152 1.00 17.21 ?  145  THR B HG22 1 
ATOM   7861  H HG23 . THR B 1 179 ? 16.351  37.115  39.880 1.00 17.21 ?  145  THR B HG23 1 
ATOM   7862  N N    . LYS B 1 180 ? 16.821  41.017  37.300 1.00 11.96 ?  146  LYS B N    1 
ATOM   7863  C CA   . LYS B 1 180 ? 17.346  41.956  36.316 1.00 14.46 ?  146  LYS B CA   1 
ATOM   7864  C C    . LYS B 1 180 ? 16.789  43.352  36.575 1.00 16.06 ?  146  LYS B C    1 
ATOM   7865  O O    . LYS B 1 180 ? 15.572  43.533  36.699 1.00 12.65 ?  146  LYS B O    1 
ATOM   7866  C CB   . LYS B 1 180 ? 16.955  41.495  34.918 1.00 12.71 ?  146  LYS B CB   1 
ATOM   7867  C CG   . LYS B 1 180 ? 17.552  40.145  34.596 1.00 14.60 ?  146  LYS B CG   1 
ATOM   7868  C CD   . LYS B 1 180 ? 17.413  39.736  33.179 1.00 16.23 ?  146  LYS B CD   1 
ATOM   7869  C CE   . LYS B 1 180 ? 18.207  38.460  32.939 1.00 22.19 ?  146  LYS B CE   1 
ATOM   7870  N NZ   . LYS B 1 180 ? 17.818  37.788  31.714 1.00 25.21 ?  146  LYS B NZ   1 
ATOM   7871  H H    . LYS B 1 180 ? 16.085  40.640  37.065 1.00 14.35 ?  146  LYS B H    1 
ATOM   7872  H HA   . LYS B 1 180 ? 18.312  42.001  36.384 1.00 17.36 ?  146  LYS B HA   1 
ATOM   7873  H HB2  . LYS B 1 180 ? 15.990  41.424  34.862 1.00 15.25 ?  146  LYS B HB2  1 
ATOM   7874  H HB3  . LYS B 1 180 ? 17.279  42.136  34.267 1.00 15.25 ?  146  LYS B HB3  1 
ATOM   7875  H HG2  . LYS B 1 180 ? 18.500  40.168  34.802 1.00 17.52 ?  146  LYS B HG2  1 
ATOM   7876  H HG3  . LYS B 1 180 ? 17.111  39.473  35.139 1.00 17.52 ?  146  LYS B HG3  1 
ATOM   7877  H HD2  . LYS B 1 180 ? 16.480  39.567  32.975 1.00 19.48 ?  146  LYS B HD2  1 
ATOM   7878  H HD3  . LYS B 1 180 ? 17.758  40.433  32.600 1.00 19.48 ?  146  LYS B HD3  1 
ATOM   7879  H HE2  . LYS B 1 180 ? 19.150  38.679  32.876 1.00 26.62 ?  146  LYS B HE2  1 
ATOM   7880  H HE3  . LYS B 1 180 ? 18.058  37.849  33.678 1.00 26.62 ?  146  LYS B HE3  1 
ATOM   7881  H HZ1  . LYS B 1 180 ? 18.316  37.061  31.594 1.00 30.25 ?  146  LYS B HZ1  1 
ATOM   7882  H HZ2  . LYS B 1 180 ? 16.962  37.548  31.758 1.00 30.25 ?  146  LYS B HZ2  1 
ATOM   7883  H HZ3  . LYS B 1 180 ? 17.930  38.333  31.020 1.00 30.25 ?  146  LYS B HZ3  1 
ATOM   7884  N N    . SER B 1 181 ? 17.678  44.344  36.617 1.00 14.35 ?  147  SER B N    1 
ATOM   7885  C CA   . SER B 1 181 ? 17.259  45.689  36.983 1.00 12.69 ?  147  SER B CA   1 
ATOM   7886  C C    . SER B 1 181 ? 16.176  46.215  36.038 1.00 13.12 ?  147  SER B C    1 
ATOM   7887  O O    . SER B 1 181 ? 15.203  46.834  36.495 1.00 13.00 ?  147  SER B O    1 
ATOM   7888  C CB   . SER B 1 181 ? 18.479  46.615  37.028 1.00 16.53 ?  147  SER B CB   1 
ATOM   7889  O OG   . SER B 1 181 ? 18.091  47.959  36.819 1.00 26.30 ?  147  SER B OG   1 
ATOM   7890  H H    . SER B 1 181 ? 18.516  44.264  36.441 1.00 17.22 ?  147  SER B H    1 
ATOM   7891  H HA   . SER B 1 181 ? 16.872  45.674  37.872 1.00 15.23 ?  147  SER B HA   1 
ATOM   7892  H HB2  . SER B 1 181 ? 18.903  46.539  37.897 1.00 19.84 ?  147  SER B HB2  1 
ATOM   7893  H HB3  . SER B 1 181 ? 19.102  46.354  36.332 1.00 19.84 ?  147  SER B HB3  1 
ATOM   7894  N N    . PHE B 1 182 ? 16.292  45.972  34.726 1.00 12.76 ?  148  PHE B N    1 
ATOM   7895  C CA   . PHE B 1 182 ? 15.304  46.532  33.804 1.00 12.08 ?  148  PHE B CA   1 
ATOM   7896  C C    . PHE B 1 182 ? 13.930  45.919  34.046 1.00 12.76 ?  148  PHE B C    1 
ATOM   7897  O O    . PHE B 1 182 ? 12.906  46.564  33.790 1.00 12.77 ?  148  PHE B O    1 
ATOM   7898  C CB   . PHE B 1 182 ? 15.755  46.446  32.333 1.00 13.93 ?  148  PHE B CB   1 
ATOM   7899  C CG   . PHE B 1 182 ? 15.514  45.109  31.669 1.00 14.18 ?  148  PHE B CG   1 
ATOM   7900  C CD1  . PHE B 1 182 ? 16.450  44.086  31.755 1.00 15.33 ?  148  PHE B CD1  1 
ATOM   7901  C CD2  . PHE B 1 182 ? 14.383  44.902  30.891 1.00 15.41 ?  148  PHE B CD2  1 
ATOM   7902  C CE1  . PHE B 1 182 ? 16.233  42.867  31.126 1.00 15.96 ?  148  PHE B CE1  1 
ATOM   7903  C CE2  . PHE B 1 182 ? 14.161  43.691  30.257 1.00 15.29 ?  148  PHE B CE2  1 
ATOM   7904  C CZ   . PHE B 1 182 ? 15.090  42.673  30.374 1.00 15.69 ?  148  PHE B CZ   1 
ATOM   7905  H H    . PHE B 1 182 ? 16.912  45.502  34.359 1.00 15.32 ?  148  PHE B H    1 
ATOM   7906  H HA   . PHE B 1 182 ? 15.230  47.485  33.968 1.00 14.50 ?  148  PHE B HA   1 
ATOM   7907  H HB2  . PHE B 1 182 ? 15.271  47.115  31.824 1.00 16.72 ?  148  PHE B HB2  1 
ATOM   7908  H HB3  . PHE B 1 182 ? 16.708  46.624  32.293 1.00 16.72 ?  148  PHE B HB3  1 
ATOM   7909  H HD1  . PHE B 1 182 ? 17.233  44.220  32.239 1.00 18.39 ?  148  PHE B HD1  1 
ATOM   7910  H HD2  . PHE B 1 182 ? 13.763  45.589  30.794 1.00 18.49 ?  148  PHE B HD2  1 
ATOM   7911  H HE1  . PHE B 1 182 ? 16.857  42.182  31.211 1.00 19.16 ?  148  PHE B HE1  1 
ATOM   7912  H HE2  . PHE B 1 182 ? 13.389  43.562  29.755 1.00 18.35 ?  148  PHE B HE2  1 
ATOM   7913  H HZ   . PHE B 1 182 ? 14.945  41.859  29.946 1.00 18.83 ?  148  PHE B HZ   1 
ATOM   7914  N N    . VAL B 1 183 ? 13.896  44.677  34.534 1.00 11.80 ?  149  VAL B N    1 
ATOM   7915  C CA   . VAL B 1 183 ? 12.617  44.050  34.867 1.00 12.06 ?  149  VAL B CA   1 
ATOM   7916  C C    . VAL B 1 183 ? 12.051  44.655  36.140 1.00 9.93  ?  149  VAL B C    1 
ATOM   7917  O O    . VAL B 1 183 ? 10.848  44.939  36.221 1.00 10.55 ?  149  VAL B O    1 
ATOM   7918  C CB   . VAL B 1 183 ? 12.779  42.524  34.981 1.00 12.20 ?  149  VAL B CB   1 
ATOM   7919  C CG1  . VAL B 1 183 ? 11.472  41.874  35.450 1.00 11.78 ?  149  VAL B CG1  1 
ATOM   7920  C CG2  . VAL B 1 183 ? 13.228  41.935  33.662 1.00 12.51 ?  149  VAL B CG2  1 
ATOM   7921  H H    . VAL B 1 183 ? 14.586  44.185  34.678 1.00 14.16 ?  149  VAL B H    1 
ATOM   7922  H HA   . VAL B 1 183 ? 11.991  44.225  34.147 1.00 14.48 ?  149  VAL B HA   1 
ATOM   7923  H HB   . VAL B 1 183 ? 13.461  42.332  35.643 1.00 14.64 ?  149  VAL B HB   1 
ATOM   7924  H HG11 . VAL B 1 183 ? 11.524  40.917  35.301 1.00 14.13 ?  149  VAL B HG11 1 
ATOM   7925  H HG12 . VAL B 1 183 ? 11.351  42.055  36.395 1.00 14.13 ?  149  VAL B HG12 1 
ATOM   7926  H HG13 . VAL B 1 183 ? 10.734  42.248  34.944 1.00 14.13 ?  149  VAL B HG13 1 
ATOM   7927  H HG21 . VAL B 1 183 ? 13.317  40.974  33.758 1.00 15.02 ?  149  VAL B HG21 1 
ATOM   7928  H HG22 . VAL B 1 183 ? 12.566  42.140  32.983 1.00 15.02 ?  149  VAL B HG22 1 
ATOM   7929  H HG23 . VAL B 1 183 ? 14.083  42.324  33.417 1.00 15.02 ?  149  VAL B HG23 1 
ATOM   7930  N N    . GLN B 1 184 ? 12.885  44.834  37.158 1.00 10.69 ?  150  GLN B N    1 
ATOM   7931  C CA   . GLN B 1 184 ? 12.441  45.517  38.366 1.00 11.65 ?  150  GLN B CA   1 
ATOM   7932  C C    . GLN B 1 184 ? 11.830  46.869  38.035 1.00 11.95 ?  150  GLN B C    1 
ATOM   7933  O O    . GLN B 1 184 ? 10.779  47.242  38.571 1.00 11.80 ?  150  GLN B O    1 
ATOM   7934  C CB   . GLN B 1 184 ? 13.622  45.726  39.314 1.00 11.82 ?  150  GLN B CB   1 
ATOM   7935  C CG   . GLN B 1 184 ? 14.267  44.448  39.802 1.00 12.20 ?  150  GLN B CG   1 
ATOM   7936  C CD   . GLN B 1 184 ? 15.582  44.701  40.505 1.00 14.40 ?  150  GLN B CD   1 
ATOM   7937  O OE1  . GLN B 1 184 ? 15.850  45.814  40.976 1.00 16.96 ?  150  GLN B OE1  1 
ATOM   7938  N NE2  . GLN B 1 184 ? 16.394  43.676  40.610 1.00 13.65 ?  150  GLN B NE2  1 
ATOM   7939  H H    . GLN B 1 184 ? 13.704  44.573  37.174 1.00 12.83 ?  150  GLN B H    1 
ATOM   7940  H HA   . GLN B 1 184 ? 11.776  44.961  38.802 1.00 13.98 ?  150  GLN B HA   1 
ATOM   7941  H HB2  . GLN B 1 184 ? 14.302  46.240  38.851 1.00 14.18 ?  150  GLN B HB2  1 
ATOM   7942  H HB3  . GLN B 1 184 ? 13.311  46.214  40.093 1.00 14.18 ?  150  GLN B HB3  1 
ATOM   7943  H HG2  . GLN B 1 184 ? 13.670  44.009  40.428 1.00 14.64 ?  150  GLN B HG2  1 
ATOM   7944  H HG3  . GLN B 1 184 ? 14.437  43.868  39.044 1.00 14.64 ?  150  GLN B HG3  1 
ATOM   7945  H HE21 . GLN B 1 184 ? 16.165  42.912  40.287 1.00 16.38 ?  150  GLN B HE21 1 
ATOM   7946  H HE22 . GLN B 1 184 ? 17.154  43.768  41.001 1.00 16.38 ?  150  GLN B HE22 1 
ATOM   7947  N N    . GLU B 1 185 ? 12.493  47.636  37.169 1.00 11.46 ?  151  GLU B N    1 
ATOM   7948  C CA   . GLU B 1 185 ? 12.040  48.992  36.889 1.00 11.92 ?  151  GLU B CA   1 
ATOM   7949  C C    . GLU B 1 185 ? 10.749  48.977  36.086 1.00 11.12 ?  151  GLU B C    1 
ATOM   7950  O O    . GLU B 1 185 ? 9.842   49.783  36.338 1.00 11.33 ?  151  GLU B O    1 
ATOM   7951  C CB   . GLU B 1 185 ? 13.141  49.782  36.166 1.00 13.17 ?  151  GLU B CB   1 
ATOM   7952  C CG   . GLU B 1 185 ? 14.433  49.960  36.972 1.00 15.26 ?  151  GLU B CG   1 
ATOM   7953  C CD   . GLU B 1 185 ? 14.230  50.736  38.258 1.00 16.62 ?  151  GLU B CD   1 
ATOM   7954  O OE1  . GLU B 1 185 ? 13.331  51.611  38.293 1.00 17.35 ?  151  GLU B OE1  1 
ATOM   7955  O OE2  . GLU B 1 185 ? 14.941  50.467  39.249 1.00 20.06 ?  151  GLU B OE2  1 
ATOM   7956  H H    . GLU B 1 185 ? 13.197  47.397  36.737 1.00 13.75 ?  151  GLU B H    1 
ATOM   7957  H HA   . GLU B 1 185 ? 11.862  49.449  37.726 1.00 14.31 ?  151  GLU B HA   1 
ATOM   7958  H HB2  . GLU B 1 185 ? 13.370  49.314  35.348 1.00 15.80 ?  151  GLU B HB2  1 
ATOM   7959  H HB3  . GLU B 1 185 ? 12.801  50.666  35.960 1.00 15.80 ?  151  GLU B HB3  1 
ATOM   7960  H HG2  . GLU B 1 185 ? 14.783  49.086  37.204 1.00 18.31 ?  151  GLU B HG2  1 
ATOM   7961  H HG3  . GLU B 1 185 ? 15.078  50.443  36.431 1.00 18.31 ?  151  GLU B HG3  1 
ATOM   7962  N N    . TYR B 1 186 ? 10.636  48.066  35.116 1.00 10.74 ?  152  TYR B N    1 
ATOM   7963  C CA   . TYR B 1 186 ? 9.378   47.924  34.388 1.00 10.06 ?  152  TYR B CA   1 
ATOM   7964  C C    . TYR B 1 186 ? 8.239   47.587  35.348 1.00 10.29 ?  152  TYR B C    1 
ATOM   7965  O O    . TYR B 1 186 ? 7.154   48.186  35.301 1.00 10.18 ?  152  TYR B O    1 
ATOM   7966  C CB   . TYR B 1 186 ? 9.477   46.825  33.317 1.00 11.69 ?  152  TYR B CB   1 
ATOM   7967  C CG   . TYR B 1 186 ? 8.105   46.561  32.727 1.00 10.31 ?  152  TYR B CG   1 
ATOM   7968  C CD1  . TYR B 1 186 ? 7.599   47.384  31.742 1.00 11.17 ?  152  TYR B CD1  1 
ATOM   7969  C CD2  . TYR B 1 186 ? 7.290   45.536  33.204 1.00 10.26 ?  152  TYR B CD2  1 
ATOM   7970  C CE1  . TYR B 1 186 ? 6.334   47.228  31.248 1.00 10.90 ?  152  TYR B CE1  1 
ATOM   7971  C CE2  . TYR B 1 186 ? 6.025   45.355  32.702 1.00 9.86  ?  152  TYR B CE2  1 
ATOM   7972  C CZ   . TYR B 1 186 ? 5.535   46.201  31.736 1.00 9.24  ?  152  TYR B CZ   1 
ATOM   7973  O OH   . TYR B 1 186 ? 4.271   46.061  31.232 1.00 11.69 ?  152  TYR B OH   1 
ATOM   7974  H H    . TYR B 1 186 ? 11.260  47.530  34.866 1.00 12.88 ?  152  TYR B H    1 
ATOM   7975  H HA   . TYR B 1 186 ? 9.196   48.766  33.942 1.00 12.07 ?  152  TYR B HA   1 
ATOM   7976  H HB2  . TYR B 1 186 ? 10.073  47.112  32.607 1.00 14.03 ?  152  TYR B HB2  1 
ATOM   7977  H HB3  . TYR B 1 186 ? 9.808   46.006  33.718 1.00 14.03 ?  152  TYR B HB3  1 
ATOM   7978  H HD1  . TYR B 1 186 ? 8.134   48.065  31.404 1.00 13.41 ?  152  TYR B HD1  1 
ATOM   7979  H HD2  . TYR B 1 186 ? 7.606   44.968  33.869 1.00 12.31 ?  152  TYR B HD2  1 
ATOM   7980  H HE1  . TYR B 1 186 ? 6.011   47.803  30.592 1.00 13.08 ?  152  TYR B HE1  1 
ATOM   7981  H HE2  . TYR B 1 186 ? 5.498   44.657  33.018 1.00 11.83 ?  152  TYR B HE2  1 
ATOM   7982  H HH   . TYR B 1 186 ? 3.826   45.536  31.714 1.00 14.03 ?  152  TYR B HH   1 
ATOM   7983  N N    . TRP B 1 187 ? 8.473   46.620  36.230 1.00 9.78  ?  153  TRP B N    1 
ATOM   7984  C CA   . TRP B 1 187 ? 7.418   46.163  37.127 1.00 9.53  ?  153  TRP B CA   1 
ATOM   7985  C C    . TRP B 1 187 ? 7.008   47.270  38.091 1.00 9.73  ?  153  TRP B C    1 
ATOM   7986  O O    . TRP B 1 187 ? 5.814   47.565  38.244 1.00 9.24  ?  153  TRP B O    1 
ATOM   7987  C CB   . TRP B 1 187 ? 7.884   44.906  37.865 1.00 9.48  ?  153  TRP B CB   1 
ATOM   7988  C CG   . TRP B 1 187 ? 6.800   44.215  38.641 1.00 9.00  ?  153  TRP B CG   1 
ATOM   7989  C CD1  . TRP B 1 187 ? 6.016   43.176  38.215 1.00 9.38  ?  153  TRP B CD1  1 
ATOM   7990  C CD2  . TRP B 1 187 ? 6.410   44.488  39.990 1.00 9.45  ?  153  TRP B CD2  1 
ATOM   7991  N NE1  . TRP B 1 187 ? 5.148   42.812  39.218 1.00 8.39  ?  153  TRP B NE1  1 
ATOM   7992  C CE2  . TRP B 1 187 ? 5.368   43.602  40.311 1.00 8.45  ?  153  TRP B CE2  1 
ATOM   7993  C CE3  . TRP B 1 187 ? 6.837   45.408  40.957 1.00 9.81  ?  153  TRP B CE3  1 
ATOM   7994  C CZ2  . TRP B 1 187 ? 4.748   43.610  41.552 1.00 8.57  ?  153  TRP B CZ2  1 
ATOM   7995  C CZ3  . TRP B 1 187 ? 6.227   45.402  42.199 1.00 9.68  ?  153  TRP B CZ3  1 
ATOM   7996  C CH2  . TRP B 1 187 ? 5.197   44.505  42.491 1.00 9.42  ?  153  TRP B CH2  1 
ATOM   7997  H H    . TRP B 1 187 ? 9.226   46.217  36.329 1.00 11.74 ?  153  TRP B H    1 
ATOM   7998  H HA   . TRP B 1 187 ? 6.631   45.924  36.613 1.00 11.44 ?  153  TRP B HA   1 
ATOM   7999  H HB2  . TRP B 1 187 ? 8.231   44.275  37.216 1.00 11.38 ?  153  TRP B HB2  1 
ATOM   8000  H HB3  . TRP B 1 187 ? 8.582   45.155  38.492 1.00 11.38 ?  153  TRP B HB3  1 
ATOM   8001  H HD1  . TRP B 1 187 ? 6.063   42.777  37.376 1.00 11.26 ?  153  TRP B HD1  1 
ATOM   8002  H HE1  . TRP B 1 187 ? 4.560   42.186  39.165 1.00 10.07 ?  153  TRP B HE1  1 
ATOM   8003  H HE3  . TRP B 1 187 ? 7.517   46.013  40.767 1.00 11.77 ?  153  TRP B HE3  1 
ATOM   8004  H HZ2  . TRP B 1 187 ? 4.049   43.027  41.742 1.00 10.29 ?  153  TRP B HZ2  1 
ATOM   8005  H HZ3  . TRP B 1 187 ? 6.507   46.004  42.850 1.00 11.61 ?  153  TRP B HZ3  1 
ATOM   8006  H HH2  . TRP B 1 187 ? 4.809   44.515  43.336 1.00 11.31 ?  153  TRP B HH2  1 
ATOM   8007  N N    . LEU B 1 188 ? 7.983   47.889  38.763 1.00 10.31 ?  154  LEU B N    1 
ATOM   8008  C CA   . LEU B 1 188 ? 7.670   48.957  39.706 1.00 9.60  ?  154  LEU B CA   1 
ATOM   8009  C C    . LEU B 1 188 ? 6.911   50.090  39.029 1.00 9.88  ?  154  LEU B C    1 
ATOM   8010  O O    . LEU B 1 188 ? 5.916   50.587  39.566 1.00 10.11 ?  154  LEU B O    1 
ATOM   8011  C CB   . LEU B 1 188 ? 8.950   49.494  40.360 1.00 10.73 ?  154  LEU B CB   1 
ATOM   8012  C CG   . LEU B 1 188 ? 9.618   48.531  41.345 1.00 11.31 ?  154  LEU B CG   1 
ATOM   8013  C CD1  . LEU B 1 188 ? 11.043  49.002  41.614 1.00 11.84 ?  154  LEU B CD1  1 
ATOM   8014  C CD2  . LEU B 1 188 ? 8.829   48.414  42.636 1.00 12.64 ?  154  LEU B CD2  1 
ATOM   8015  H H    . LEU B 1 188 ? 8.821   47.710  38.690 1.00 12.37 ?  154  LEU B H    1 
ATOM   8016  H HA   . LEU B 1 188 ? 7.108   48.586  40.404 1.00 11.52 ?  154  LEU B HA   1 
ATOM   8017  H HB2  . LEU B 1 188 ? 9.593   49.691  39.661 1.00 12.87 ?  154  LEU B HB2  1 
ATOM   8018  H HB3  . LEU B 1 188 ? 8.730   50.304  40.847 1.00 12.87 ?  154  LEU B HB3  1 
ATOM   8019  H HG   . LEU B 1 188 ? 9.646   47.642  40.958 1.00 13.57 ?  154  LEU B HG   1 
ATOM   8020  H HD11 . LEU B 1 188 ? 11.185  49.046  42.572 1.00 14.21 ?  154  LEU B HD11 1 
ATOM   8021  H HD12 . LEU B 1 188 ? 11.664  48.372  41.216 1.00 14.21 ?  154  LEU B HD12 1 
ATOM   8022  H HD13 . LEU B 1 188 ? 11.165  49.880  41.220 1.00 14.21 ?  154  LEU B HD13 1 
ATOM   8023  H HD21 . LEU B 1 188 ? 9.333   47.878  43.267 1.00 15.16 ?  154  LEU B HD21 1 
ATOM   8024  H HD22 . LEU B 1 188 ? 8.683   49.302  42.999 1.00 15.16 ?  154  LEU B HD22 1 
ATOM   8025  H HD23 . LEU B 1 188 ? 7.977   47.990  42.448 1.00 15.16 ?  154  LEU B HD23 1 
ATOM   8026  N N    . LYS B 1 189 ? 7.362   50.518  37.849 1.00 10.60 ?  155  LYS B N    1 
ATOM   8027  C CA   . LYS B 1 189 ? 6.683   51.610  37.166 1.00 10.70 ?  155  LYS B CA   1 
ATOM   8028  C C    . LYS B 1 189 ? 5.274   51.197  36.767 1.00 10.80 ?  155  LYS B C    1 
ATOM   8029  O O    . LYS B 1 189 ? 4.348   52.007  36.813 1.00 11.32 ?  155  LYS B O    1 
ATOM   8030  C CB   . LYS B 1 189 ? 7.503   52.054  35.951 1.00 12.98 ?  155  LYS B CB   1 
ATOM   8031  C CG   . LYS B 1 189 ? 6.812   53.070  35.066 1.00 16.95 ?  155  LYS B CG   1 
ATOM   8032  C CD   . LYS B 1 189 ? 7.787   53.625  34.028 1.00 20.82 ?  155  LYS B CD   1 
ATOM   8033  C CE   . LYS B 1 189 ? 7.051   54.133  32.801 1.00 28.74 ?  155  LYS B CE   1 
ATOM   8034  N NZ   . LYS B 1 189 ? 6.245   55.311  33.150 1.00 26.01 ?  155  LYS B NZ   1 
ATOM   8035  H H    . LYS B 1 189 ? 8.044   50.198  37.434 1.00 12.71 ?  155  LYS B H    1 
ATOM   8036  H HA   . LYS B 1 189 ? 6.611   52.373  37.760 1.00 12.84 ?  155  LYS B HA   1 
ATOM   8037  H HB2  . LYS B 1 189 ? 8.330   52.453  36.265 1.00 15.57 ?  155  LYS B HB2  1 
ATOM   8038  H HB3  . LYS B 1 189 ? 7.697   51.275  35.407 1.00 15.57 ?  155  LYS B HB3  1 
ATOM   8039  H HG2  . LYS B 1 189 ? 6.073   52.647  34.602 1.00 20.34 ?  155  LYS B HG2  1 
ATOM   8040  H HG3  . LYS B 1 189 ? 6.487   53.805  35.609 1.00 20.34 ?  155  LYS B HG3  1 
ATOM   8041  H HD2  . LYS B 1 189 ? 8.284   54.363  34.414 1.00 24.99 ?  155  LYS B HD2  1 
ATOM   8042  H HD3  . LYS B 1 189 ? 8.397   52.924  33.751 1.00 24.99 ?  155  LYS B HD3  1 
ATOM   8043  H HE2  . LYS B 1 189 ? 7.691   54.385  32.117 1.00 34.49 ?  155  LYS B HE2  1 
ATOM   8044  H HE3  . LYS B 1 189 ? 6.461   53.441  32.464 1.00 34.49 ?  155  LYS B HE3  1 
ATOM   8045  H HZ1  . LYS B 1 189 ? 5.563   55.070  33.668 1.00 31.21 ?  155  LYS B HZ1  1 
ATOM   8046  H HZ2  . LYS B 1 189 ? 6.745   55.903  33.588 1.00 31.21 ?  155  LYS B HZ2  1 
ATOM   8047  H HZ3  . LYS B 1 189 ? 5.928   55.692  32.411 1.00 31.21 ?  155  LYS B HZ3  1 
ATOM   8048  N N    . SER B 1 190 ? 5.073   49.935  36.382 1.00 10.41 ?  156  SER B N    1 
ATOM   8049  C CA   . SER B 1 190 ? 3.731   49.515  36.005 1.00 9.35  ?  156  SER B CA   1 
ATOM   8050  C C    . SER B 1 190 ? 2.778   49.656  37.180 1.00 9.70  ?  156  SER B C    1 
ATOM   8051  O O    . SER B 1 190 ? 1.628   50.081  37.008 1.00 10.03 ?  156  SER B O    1 
ATOM   8052  C CB   . SER B 1 190 ? 3.744   48.089  35.434 1.00 10.12 ?  156  SER B CB   1 
ATOM   8053  O OG   . SER B 1 190 ? 3.864   47.078  36.432 1.00 9.80  ?  156  SER B OG   1 
ATOM   8054  H H    . SER B 1 190 ? 5.678   49.326  36.333 1.00 12.49 ?  156  SER B H    1 
ATOM   8055  H HA   . SER B 1 190 ? 3.404   50.085  35.291 1.00 11.22 ?  156  SER B HA   1 
ATOM   8056  H HB2  . SER B 1 190 ? 2.915   47.945  34.953 1.00 12.14 ?  156  SER B HB2  1 
ATOM   8057  H HB3  . SER B 1 190 ? 4.498   48.010  34.828 1.00 12.14 ?  156  SER B HB3  1 
ATOM   8058  H HG   . SER B 1 190 ? 4.525   47.237  36.925 1.00 11.77 ?  156  SER B HG   1 
ATOM   8059  N N    . VAL B 1 191 ? 3.245   49.321  38.385 1.00 8.85  ?  157  VAL B N    1 
ATOM   8060  C CA   . VAL B 1 191 ? 2.412   49.452  39.578 1.00 9.73  ?  157  VAL B CA   1 
ATOM   8061  C C    . VAL B 1 191 ? 2.192   50.918  39.924 1.00 9.39  ?  157  VAL B C    1 
ATOM   8062  O O    . VAL B 1 191 ? 1.065   51.355  40.187 1.00 10.06 ?  157  VAL B O    1 
ATOM   8063  C CB   . VAL B 1 191 ? 3.019   48.679  40.762 1.00 8.54  ?  157  VAL B CB   1 
ATOM   8064  C CG1  . VAL B 1 191 ? 2.219   48.924  42.019 1.00 9.76  ?  157  VAL B CG1  1 
ATOM   8065  C CG2  . VAL B 1 191 ? 3.059   47.190  40.451 1.00 9.29  ?  157  VAL B CG2  1 
ATOM   8066  H H    . VAL B 1 191 ? 4.036   49.017  38.537 1.00 10.62 ?  157  VAL B H    1 
ATOM   8067  H HA   . VAL B 1 191 ? 1.547   49.058  39.380 1.00 11.68 ?  157  VAL B HA   1 
ATOM   8068  H HB   . VAL B 1 191 ? 3.925   48.992  40.909 1.00 10.25 ?  157  VAL B HB   1 
ATOM   8069  H HG11 . VAL B 1 191 ? 2.537   48.328  42.716 1.00 11.72 ?  157  VAL B HG11 1 
ATOM   8070  H HG12 . VAL B 1 191 ? 2.336   49.847  42.293 1.00 11.72 ?  157  VAL B HG12 1 
ATOM   8071  H HG13 . VAL B 1 191 ? 1.283   48.749  41.836 1.00 11.72 ?  157  VAL B HG13 1 
ATOM   8072  H HG21 . VAL B 1 191 ? 3.546   46.733  41.155 1.00 11.15 ?  157  VAL B HG21 1 
ATOM   8073  H HG22 . VAL B 1 191 ? 2.151   46.852  40.405 1.00 11.15 ?  157  VAL B HG22 1 
ATOM   8074  H HG23 . VAL B 1 191 ? 3.505   47.057  39.600 1.00 11.15 ?  157  VAL B HG23 1 
ATOM   8075  N N    . GLU B 1 192 ? 3.275   51.683  39.978 1.00 9.07  ?  158  GLU B N    1 
ATOM   8076  C CA   . GLU B 1 192 ? 3.188   53.089  40.345 1.00 9.55  ?  158  GLU B CA   1 
ATOM   8077  C C    . GLU B 1 192 ? 2.326   53.865  39.362 1.00 10.40 ?  158  GLU B C    1 
ATOM   8078  O O    . GLU B 1 192 ? 1.502   54.690  39.780 1.00 10.29 ?  158  GLU B O    1 
ATOM   8079  C CB   . GLU B 1 192 ? 4.605   53.663  40.430 1.00 10.80 ?  158  GLU B CB   1 
ATOM   8080  C CG   . GLU B 1 192 ? 5.396   53.101  41.602 1.00 11.92 ?  158  GLU B CG   1 
ATOM   8081  C CD   . GLU B 1 192 ? 6.904   53.311  41.532 1.00 14.17 ?  158  GLU B CD   1 
ATOM   8082  O OE1  . GLU B 1 192 ? 7.401   53.797  40.504 1.00 18.07 ?  158  GLU B OE1  1 
ATOM   8083  O OE2  . GLU B 1 192 ? 7.582   52.952  42.529 1.00 15.72 ?  158  GLU B OE2  1 
ATOM   8084  H H    . GLU B 1 192 ? 4.073   51.413  39.808 1.00 10.89 ?  158  GLU B H    1 
ATOM   8085  H HA   . GLU B 1 192 ? 2.771   53.179  41.215 1.00 11.46 ?  158  GLU B HA   1 
ATOM   8086  H HB2  . GLU B 1 192 ? 5.083   53.448  39.614 1.00 12.96 ?  158  GLU B HB2  1 
ATOM   8087  H HB3  . GLU B 1 192 ? 4.549   54.626  40.538 1.00 12.96 ?  158  GLU B HB3  1 
ATOM   8088  H HG2  . GLU B 1 192 ? 5.082   53.527  42.416 1.00 14.31 ?  158  GLU B HG2  1 
ATOM   8089  H HG3  . GLU B 1 192 ? 5.239   52.145  41.647 1.00 14.31 ?  158  GLU B HG3  1 
ATOM   8090  N N    . ASP B 1 193 ? 2.460   53.587  38.067 1.00 9.88  ?  159  ASP B N    1 
ATOM   8091  C CA   . ASP B 1 193 ? 1.640   54.285  37.085 1.00 11.16 ?  159  ASP B CA   1 
ATOM   8092  C C    . ASP B 1 193 ? 0.156   53.977  37.271 1.00 10.23 ?  159  ASP B C    1 
ATOM   8093  O O    . ASP B 1 193 ? -0.685  54.871  37.157 1.00 12.43 ?  159  ASP B O    1 
ATOM   8094  C CB   . ASP B 1 193 ? 2.056   53.930  35.657 1.00 11.18 ?  159  ASP B CB   1 
ATOM   8095  C CG   . ASP B 1 193 ? 3.333   54.610  35.217 1.00 12.37 ?  159  ASP B CG   1 
ATOM   8096  O OD1  . ASP B 1 193 ? 3.847   55.471  35.949 1.00 16.53 ?  159  ASP B OD1  1 
ATOM   8097  O OD2  . ASP B 1 193 ? 3.813   54.245  34.133 1.00 16.45 ?  159  ASP B OD2  1 
ATOM   8098  H H    . ASP B 1 193 ? 3.008   53.011  37.738 1.00 11.85 ?  159  ASP B H    1 
ATOM   8099  H HA   . ASP B 1 193 ? 1.785   55.235  37.214 1.00 13.39 ?  159  ASP B HA   1 
ATOM   8100  H HB2  . ASP B 1 193 ? 2.195   52.972  35.599 1.00 13.42 ?  159  ASP B HB2  1 
ATOM   8101  H HB3  . ASP B 1 193 ? 1.351   54.201  35.048 1.00 13.42 ?  159  ASP B HB3  1 
ATOM   8102  N N    . MET B 1 194 ? -0.207  52.702  37.486 1.00 8.76  ?  160  MET B N    1 
ATOM   8103  C CA   . MET B 1 194 ? -1.627  52.389  37.671 1.00 8.41  ?  160  MET B CA   1 
ATOM   8104  C C    . MET B 1 194 ? -2.166  52.992  38.961 1.00 9.24  ?  160  MET B C    1 
ATOM   8105  O O    . MET B 1 194 ? -3.283  53.537  38.985 1.00 9.52  ?  160  MET B O    1 
ATOM   8106  C CB   . MET B 1 194 ? -1.841  50.874  37.681 1.00 9.22  ?  160  MET B CB   1 
ATOM   8107  C CG   . MET B 1 194 ? -3.287  50.431  37.672 1.00 8.09  ?  160  MET B CG   1 
ATOM   8108  S SD   . MET B 1 194 ? -4.307  51.037  36.310 1.00 10.67 ?  160  MET B SD   1 
ATOM   8109  C CE   . MET B 1 194 ? -3.914  49.794  35.081 1.00 14.07 ?  160  MET B CE   1 
ATOM   8110  H H    . MET B 1 194 ? 0.329   52.031  37.527 1.00 10.51 ?  160  MET B H    1 
ATOM   8111  H HA   . MET B 1 194 ? -2.112  52.760  36.917 1.00 10.09 ?  160  MET B HA   1 
ATOM   8112  H HB2  . MET B 1 194 ? -1.418  50.499  36.893 1.00 11.06 ?  160  MET B HB2  1 
ATOM   8113  H HB3  . MET B 1 194 ? -1.432  50.511  38.482 1.00 11.06 ?  160  MET B HB3  1 
ATOM   8114  H HG2  . MET B 1 194 ? -3.305  49.462  37.630 1.00 9.71  ?  160  MET B HG2  1 
ATOM   8115  H HG3  . MET B 1 194 ? -3.701  50.735  38.494 1.00 9.71  ?  160  MET B HG3  1 
ATOM   8116  H HE1  . MET B 1 194 ? -4.322  50.044  34.237 1.00 16.88 ?  160  MET B HE1  1 
ATOM   8117  H HE2  . MET B 1 194 ? -2.951  49.743  34.980 1.00 16.88 ?  160  MET B HE2  1 
ATOM   8118  H HE3  . MET B 1 194 ? -4.262  48.938  35.376 1.00 16.88 ?  160  MET B HE3  1 
ATOM   8119  N N    . VAL B 1 195 ? -1.402  52.901  40.050 1.00 10.03 ?  161  VAL B N    1 
ATOM   8120  C CA   . VAL B 1 195 ? -1.876  53.444  41.312 1.00 9.44  ?  161  VAL B CA   1 
ATOM   8121  C C    . VAL B 1 195 ? -2.011  54.966  41.241 1.00 10.43 ?  161  VAL B C    1 
ATOM   8122  O O    . VAL B 1 195 ? -2.850  55.545  41.935 1.00 11.60 ?  161  VAL B O    1 
ATOM   8123  C CB   . VAL B 1 195 ? -0.998  52.976  42.492 1.00 8.93  ?  161  VAL B CB   1 
ATOM   8124  C CG1  . VAL B 1 195 ? -1.401  53.682  43.786 1.00 10.88 ?  161  VAL B CG1  1 
ATOM   8125  C CG2  . VAL B 1 195 ? -1.088  51.457  42.646 1.00 9.64  ?  161  VAL B CG2  1 
ATOM   8126  H H    . VAL B 1 195 ? -0.623  52.537  40.080 1.00 12.04 ?  161  VAL B H    1 
ATOM   8127  H HA   . VAL B 1 195 ? -2.763  53.088  41.474 1.00 11.33 ?  161  VAL B HA   1 
ATOM   8128  H HB   . VAL B 1 195 ? -0.075  53.210  42.309 1.00 10.72 ?  161  VAL B HB   1 
ATOM   8129  H HG11 . VAL B 1 195 ? -0.963  53.245  44.533 1.00 13.06 ?  161  VAL B HG11 1 
ATOM   8130  H HG12 . VAL B 1 195 ? -1.124  54.610  43.738 1.00 13.06 ?  161  VAL B HG12 1 
ATOM   8131  H HG13 . VAL B 1 195 ? -2.364  53.628  43.888 1.00 13.06 ?  161  VAL B HG13 1 
ATOM   8132  H HG21 . VAL B 1 195 ? -0.434  51.167  43.301 1.00 11.56 ?  161  VAL B HG21 1 
ATOM   8133  H HG22 . VAL B 1 195 ? -1.981  51.222  42.943 1.00 11.56 ?  161  VAL B HG22 1 
ATOM   8134  H HG23 . VAL B 1 195 ? -0.904  51.042  41.789 1.00 11.56 ?  161  VAL B HG23 1 
ATOM   8135  N N    . ALA B 1 196 ? -1.230  55.636  40.388 1.00 10.09 ?  162  ALA B N    1 
ATOM   8136  C CA   . ALA B 1 196 ? -1.316  57.090  40.271 1.00 10.57 ?  162  ALA B CA   1 
ATOM   8137  C C    . ALA B 1 196 ? -2.582  57.548  39.565 1.00 10.37 ?  162  ALA B C    1 
ATOM   8138  O O    . ALA B 1 196 ? -2.907  58.735  39.641 1.00 13.18 ?  162  ALA B O    1 
ATOM   8139  C CB   . ALA B 1 196 ? -0.090  57.613  39.533 1.00 11.49 ?  162  ALA B CB   1 
ATOM   8140  H H    . ALA B 1 196 ? -0.646  55.273  39.871 1.00 12.11 ?  162  ALA B H    1 
ATOM   8141  H HA   . ALA B 1 196 ? -1.327  57.476  41.160 1.00 12.69 ?  162  ALA B HA   1 
ATOM   8142  H HB1  . ALA B 1 196 ? -0.172  58.573  39.425 1.00 13.79 ?  162  ALA B HB1  1 
ATOM   8143  H HB2  . ALA B 1 196 ? 0.703   57.405  40.052 1.00 13.79 ?  162  ALA B HB2  1 
ATOM   8144  H HB3  . ALA B 1 196 ? -0.039  57.185  38.664 1.00 13.79 ?  162  ALA B HB3  1 
ATOM   8145  N N    . THR B 1 197 ? -3.286  56.677  38.862 1.00 9.55  ?  163  THR B N    1 
ATOM   8146  C CA   . THR B 1 197 ? -4.516  57.070  38.196 1.00 10.93 ?  163  THR B CA   1 
ATOM   8147  C C    . THR B 1 197 ? -5.586  57.384  39.237 1.00 10.24 ?  163  THR B C    1 
ATOM   8148  O O    . THR B 1 197 ? -5.507  56.931  40.371 1.00 9.79  ?  163  THR B O    1 
ATOM   8149  C CB   . THR B 1 197 ? -4.966  56.018  37.184 1.00 9.85  ?  163  THR B CB   1 
ATOM   8150  O OG1  . THR B 1 197 ? -5.404  54.821  37.851 1.00 10.72 ?  163  THR B OG1  1 
ATOM   8151  C CG2  . THR B 1 197 ? -3.828  55.707  36.209 1.00 10.12 ?  163  THR B CG2  1 
ATOM   8152  H H    . THR B 1 197 ? -3.073  55.851  38.753 1.00 11.46 ?  163  THR B H    1 
ATOM   8153  H HA   . THR B 1 197 ? -4.375  57.876  37.676 1.00 13.12 ?  163  THR B HA   1 
ATOM   8154  H HB   . THR B 1 197 ? -5.717  56.360  36.674 1.00 11.82 ?  163  THR B HB   1 
ATOM   8155  H HG1  . THR B 1 197 ? -4.909  54.663  38.511 1.00 12.86 ?  163  THR B HG1  1 
ATOM   8156  H HG21 . THR B 1 197 ? -4.110  55.029  35.575 1.00 12.15 ?  163  THR B HG21 1 
ATOM   8157  H HG22 . THR B 1 197 ? -3.580  56.508  35.722 1.00 12.15 ?  163  THR B HG22 1 
ATOM   8158  H HG23 . THR B 1 197 ? -3.054  55.381  36.695 1.00 12.15 ?  163  THR B HG23 1 
ATOM   8159  N N    . PRO B 1 198 ? -6.579  58.208  38.893 1.00 8.94  ?  164  PRO B N    1 
ATOM   8160  C CA   . PRO B 1 198 ? -7.389  58.833  39.944 1.00 10.31 ?  164  PRO B CA   1 
ATOM   8161  C C    . PRO B 1 198 ? -8.348  57.898  40.659 1.00 10.38 ?  164  PRO B C    1 
ATOM   8162  O O    . PRO B 1 198 ? -8.721  58.188  41.802 1.00 13.80 ?  164  PRO B O    1 
ATOM   8163  C CB   . PRO B 1 198 ? -8.159  59.943  39.197 1.00 11.44 ?  164  PRO B CB   1 
ATOM   8164  C CG   . PRO B 1 198 ? -8.138  59.544  37.798 1.00 11.08 ?  164  PRO B CG   1 
ATOM   8165  C CD   . PRO B 1 198 ? -6.854  58.792  37.566 1.00 10.81 ?  164  PRO B CD   1 
ATOM   8166  H HA   . PRO B 1 198 ? -6.795  59.228  40.600 1.00 12.38 ?  164  PRO B HA   1 
ATOM   8167  H HB2  . PRO B 1 198 ? -9.069  59.993  39.529 1.00 13.73 ?  164  PRO B HB2  1 
ATOM   8168  H HB3  . PRO B 1 198 ? -7.713  60.795  39.322 1.00 13.73 ?  164  PRO B HB3  1 
ATOM   8169  H HG2  . PRO B 1 198 ? -8.901  58.975  37.615 1.00 13.29 ?  164  PRO B HG2  1 
ATOM   8170  H HG3  . PRO B 1 198 ? -8.172  60.336  37.238 1.00 13.29 ?  164  PRO B HG3  1 
ATOM   8171  H HD2  . PRO B 1 198 ? -6.974  58.098  36.899 1.00 12.97 ?  164  PRO B HD2  1 
ATOM   8172  H HD3  . PRO B 1 198 ? -6.143  59.393  37.296 1.00 12.97 ?  164  PRO B HD3  1 
ATOM   8173  N N    . ASN B 1 199 ? -8.763  56.795  40.039 1.00 9.64  ?  165  ASN B N    1 
ATOM   8174  C CA   . ASN B 1 199 ? -9.791  55.931  40.595 1.00 8.94  ?  165  ASN B CA   1 
ATOM   8175  C C    . ASN B 1 199 ? -9.232  54.671  41.245 1.00 8.98  ?  165  ASN B C    1 
ATOM   8176  O O    . ASN B 1 199 ? -10.015 53.803  41.649 1.00 9.83  ?  165  ASN B O    1 
ATOM   8177  C CB   . ASN B 1 199 ? -10.785 55.569  39.495 1.00 9.13  ?  165  ASN B CB   1 
ATOM   8178  C CG   . ASN B 1 199 ? -11.361 56.797  38.829 1.00 9.82  ?  165  ASN B CG   1 
ATOM   8179  O OD1  . ASN B 1 199 ? -11.157 57.040  37.615 1.00 12.86 ?  165  ASN B OD1  1 
ATOM   8180  N ND2  . ASN B 1 199 ? -12.072 57.559  39.596 1.00 8.03  ?  165  ASN B ND2  1 
ATOM   8181  H H    . ASN B 1 199 ? -8.456  56.525  39.282 1.00 11.56 ?  165  ASN B H    1 
ATOM   8182  H HA   . ASN B 1 199 ? -10.264 56.414  41.291 1.00 10.72 ?  165  ASN B HA   1 
ATOM   8183  H HB2  . ASN B 1 199 ? -10.334 55.040  38.819 1.00 10.95 ?  165  ASN B HB2  1 
ATOM   8184  H HB3  . ASN B 1 199 ? -11.516 55.062  39.881 1.00 10.95 ?  165  ASN B HB3  1 
ATOM   8185  H HD21 . ASN B 1 199 ? -12.429 58.275  39.280 1.00 9.64  ?  165  ASN B HD21 1 
ATOM   8186  H HD22 . ASN B 1 199 ? -12.187 57.351  40.422 1.00 9.64  ?  165  ASN B HD22 1 
ATOM   8187  N N    . ILE B 1 200 ? -7.915  54.571  41.358 1.00 8.35  ?  166  ILE B N    1 
ATOM   8188  C CA   . ILE B 1 200 ? -7.236  53.444  42.000 1.00 8.75  ?  166  ILE B CA   1 
ATOM   8189  C C    . ILE B 1 200 ? -6.554  53.953  43.262 1.00 8.84  ?  166  ILE B C    1 
ATOM   8190  O O    . ILE B 1 200 ? -5.863  54.981  43.241 1.00 9.08  ?  166  ILE B O    1 
ATOM   8191  C CB   . ILE B 1 200 ? -6.217  52.819  41.036 1.00 8.64  ?  166  ILE B CB   1 
ATOM   8192  C CG1  . ILE B 1 200 ? -6.922  52.206  39.829 1.00 11.34 ?  166  ILE B CG1  1 
ATOM   8193  C CG2  . ILE B 1 200 ? -5.360  51.777  41.748 1.00 9.42  ?  166  ILE B CG2  1 
ATOM   8194  C CD1  . ILE B 1 200 ? -7.677  50.952  40.119 1.00 12.65 ?  166  ILE B CD1  1 
ATOM   8195  H H    . ILE B 1 200 ? -7.369  55.165  41.059 1.00 10.03 ?  166  ILE B H    1 
ATOM   8196  H HA   . ILE B 1 200 ? -7.882  52.768  42.261 1.00 10.50 ?  166  ILE B HA   1 
ATOM   8197  H HB   . ILE B 1 200 ? -5.632  53.526  40.722 1.00 10.37 ?  166  ILE B HB   1 
ATOM   8198  H HG12 . ILE B 1 200 ? -7.554  52.854  39.480 1.00 13.61 ?  166  ILE B HG12 1 
ATOM   8199  H HG13 . ILE B 1 200 ? -6.255  51.997  39.156 1.00 13.61 ?  166  ILE B HG13 1 
ATOM   8200  H HG21 . ILE B 1 200 ? -4.805  51.324  41.094 1.00 11.31 ?  166  ILE B HG21 1 
ATOM   8201  H HG22 . ILE B 1 200 ? -4.802  52.222  42.404 1.00 11.31 ?  166  ILE B HG22 1 
ATOM   8202  H HG23 . ILE B 1 200 ? -5.942  51.137  42.187 1.00 11.31 ?  166  ILE B HG23 1 
ATOM   8203  H HD11 . ILE B 1 200 ? -8.322  50.801  39.411 1.00 15.18 ?  166  ILE B HD11 1 
ATOM   8204  H HD12 . ILE B 1 200 ? -7.053  50.211  40.162 1.00 15.18 ?  166  ILE B HD12 1 
ATOM   8205  H HD13 . ILE B 1 200 ? -8.135  51.049  40.969 1.00 15.18 ?  166  ILE B HD13 1 
ATOM   8206  N N    . ASP B 1 201 ? -6.723  53.233  44.360 1.00 8.14  ?  167  ASP B N    1 
ATOM   8207  C CA   . ASP B 1 201 ? -6.200  53.675  45.648 1.00 8.78  ?  167  ASP B CA   1 
ATOM   8208  C C    . ASP B 1 201 ? -4.953  52.940  46.095 1.00 7.75  ?  167  ASP B C    1 
ATOM   8209  O O    . ASP B 1 201 ? -4.299  53.364  47.059 1.00 9.44  ?  167  ASP B O    1 
ATOM   8210  C CB   . ASP B 1 201 ? -7.305  53.534  46.695 1.00 8.67  ?  167  ASP B CB   1 
ATOM   8211  C CG   . ASP B 1 201 ? -8.519  54.346  46.338 1.00 10.27 ?  167  ASP B CG   1 
ATOM   8212  O OD1  . ASP B 1 201 ? -8.392  55.602  46.314 1.00 11.86 ?  167  ASP B OD1  1 
ATOM   8213  O OD2  . ASP B 1 201 ? -9.574  53.767  46.060 1.00 9.76  ?  167  ASP B OD2  1 
ATOM   8214  H H    . ASP B 1 201 ? -7.139  52.481  44.387 1.00 9.76  ?  167  ASP B H    1 
ATOM   8215  H HA   . ASP B 1 201 ? -5.945  54.609  45.590 1.00 10.53 ?  167  ASP B HA   1 
ATOM   8216  H HB2  . ASP B 1 201 ? -7.569  52.603  46.758 1.00 10.40 ?  167  ASP B HB2  1 
ATOM   8217  H HB3  . ASP B 1 201 ? -6.974  53.844  47.553 1.00 10.40 ?  167  ASP B HB3  1 
ATOM   8218  N N    . GLY B 1 202 ? -4.618  51.838  45.444 1.00 8.27  ?  168  GLY B N    1 
ATOM   8219  C CA   . GLY B 1 202 ? -3.504  51.047  45.913 1.00 7.52  ?  168  GLY B CA   1 
ATOM   8220  C C    . GLY B 1 202 ? -3.382  49.778  45.106 1.00 7.69  ?  168  GLY B C    1 
ATOM   8221  O O    . GLY B 1 202 ? -3.978  49.645  44.039 1.00 7.84  ?  168  GLY B O    1 
ATOM   8222  H H    . GLY B 1 202 ? -5.013  51.536  44.742 1.00 9.93  ?  168  GLY B H    1 
ATOM   8223  H HA2  . GLY B 1 202 ? -2.681  51.553  45.827 1.00 9.02  ?  168  GLY B HA2  1 
ATOM   8224  H HA3  . GLY B 1 202 ? -3.635  50.814  46.846 1.00 9.02  ?  168  GLY B HA3  1 
ATOM   8225  N N    . THR B 1 203 ? -2.577  48.856  45.643 1.00 7.68  ?  169  THR B N    1 
ATOM   8226  C CA   . THR B 1 203 ? -2.236  47.629  44.948 1.00 7.86  ?  169  THR B CA   1 
ATOM   8227  C C    . THR B 1 203 ? -2.306  46.456  45.905 1.00 7.43  ?  169  THR B C    1 
ATOM   8228  O O    . THR B 1 203 ? -2.125  46.588  47.123 1.00 8.11  ?  169  THR B O    1 
ATOM   8229  C CB   . THR B 1 203 ? -0.865  47.779  44.268 1.00 8.51  ?  169  THR B CB   1 
ATOM   8230  O OG1  . THR B 1 203 ? -0.588  46.642  43.431 1.00 8.18  ?  169  THR B OG1  1 
ATOM   8231  C CG2  . THR B 1 203 ? 0.250   47.891  45.271 1.00 9.40  ?  169  THR B CG2  1 
ATOM   8232  H H    . THR B 1 203 ? -2.215  48.926  46.420 1.00 9.22  ?  169  THR B H    1 
ATOM   8233  H HA   . THR B 1 203 ? -2.882  47.419  44.256 1.00 9.43  ?  169  THR B HA   1 
ATOM   8234  H HB   . THR B 1 203 ? -0.894  48.590  43.737 1.00 10.21 ?  169  THR B HB   1 
ATOM   8235  H HG1  . THR B 1 203 ? -1.115  46.632  42.777 1.00 9.82  ?  169  THR B HG1  1 
ATOM   8236  H HG21 . THR B 1 203 ? 1.089   48.064  44.816 1.00 11.28 ?  169  THR B HG21 1 
ATOM   8237  H HG22 . THR B 1 203 ? 0.070   48.618  45.887 1.00 11.28 ?  169  THR B HG22 1 
ATOM   8238  H HG23 . THR B 1 203 ? 0.328   47.065  45.774 1.00 11.28 ?  169  THR B HG23 1 
ATOM   8239  N N    . PHE B 1 204 ? -2.589  45.294  45.301 1.00 7.81  ?  170  PHE B N    1 
ATOM   8240  C CA   . PHE B 1 204 ? -2.597  43.985  45.946 1.00 7.19  ?  170  PHE B CA   1 
ATOM   8241  C C    . PHE B 1 204 ? -1.400  43.242  45.362 1.00 7.21  ?  170  PHE B C    1 
ATOM   8242  O O    . PHE B 1 204 ? -1.412  42.910  44.171 1.00 7.59  ?  170  PHE B O    1 
ATOM   8243  C CB   . PHE B 1 204 ? -3.906  43.273  45.608 1.00 8.10  ?  170  PHE B CB   1 
ATOM   8244  C CG   . PHE B 1 204 ? -4.034  41.869  46.172 1.00 8.00  ?  170  PHE B CG   1 
ATOM   8245  C CD1  . PHE B 1 204 ? -3.325  40.785  45.664 1.00 8.85  ?  170  PHE B CD1  1 
ATOM   8246  C CD2  . PHE B 1 204 ? -4.916  41.653  47.201 1.00 9.08  ?  170  PHE B CD2  1 
ATOM   8247  C CE1  . PHE B 1 204 ? -3.475  39.513  46.203 1.00 8.72  ?  170  PHE B CE1  1 
ATOM   8248  C CE2  . PHE B 1 204 ? -5.086  40.387  47.734 1.00 8.67  ?  170  PHE B CE2  1 
ATOM   8249  C CZ   . PHE B 1 204 ? -4.351  39.316  47.236 1.00 9.72  ?  170  PHE B CZ   1 
ATOM   8250  H H    . PHE B 1 204 ? -2.790  45.241  44.467 1.00 9.37  ?  170  PHE B H    1 
ATOM   8251  H HA   . PHE B 1 204 ? -2.513  44.042  46.911 1.00 8.63  ?  170  PHE B HA   1 
ATOM   8252  H HB2  . PHE B 1 204 ? -4.642  43.797  45.962 1.00 9.72  ?  170  PHE B HB2  1 
ATOM   8253  H HB3  . PHE B 1 204 ? -3.980  43.207  44.643 1.00 9.72  ?  170  PHE B HB3  1 
ATOM   8254  H HD1  . PHE B 1 204 ? -2.741  40.913  44.952 1.00 10.62 ?  170  PHE B HD1  1 
ATOM   8255  H HD2  . PHE B 1 204 ? -5.405  42.365  47.544 1.00 10.90 ?  170  PHE B HD2  1 
ATOM   8256  H HE1  . PHE B 1 204 ? -2.984  38.800  45.864 1.00 10.46 ?  170  PHE B HE1  1 
ATOM   8257  H HE2  . PHE B 1 204 ? -5.692  40.252  48.426 1.00 10.41 ?  170  PHE B HE2  1 
ATOM   8258  H HZ   . PHE B 1 204 ? -4.454  38.468  47.604 1.00 11.67 ?  170  PHE B HZ   1 
ATOM   8259  N N    . ILE B 1 205 ? -0.372  43.003  46.178 1.00 7.55  ?  171  ILE B N    1 
ATOM   8260  C CA   . ILE B 1 205 ? 0.840   42.334  45.712 1.00 7.09  ?  171  ILE B CA   1 
ATOM   8261  C C    . ILE B 1 205 ? 0.729   40.848  46.004 1.00 8.17  ?  171  ILE B C    1 
ATOM   8262  O O    . ILE B 1 205 ? 0.574   40.440  47.159 1.00 8.11  ?  171  ILE B O    1 
ATOM   8263  C CB   . ILE B 1 205 ? 2.098   42.930  46.351 1.00 8.86  ?  171  ILE B CB   1 
ATOM   8264  C CG1  . ILE B 1 205 ? 2.200   44.434  46.072 1.00 9.49  ?  171  ILE B CG1  1 
ATOM   8265  C CG2  . ILE B 1 205 ? 3.341   42.216  45.839 1.00 9.71  ?  171  ILE B CG2  1 
ATOM   8266  C CD1  . ILE B 1 205 ? 2.063   44.824  44.604 1.00 11.58 ?  171  ILE B CD1  1 
ATOM   8267  H H    . ILE B 1 205 ? -0.355  43.220  47.011 1.00 9.06  ?  171  ILE B H    1 
ATOM   8268  H HA   . ILE B 1 205 ? 0.905   42.449  44.751 1.00 8.51  ?  171  ILE B HA   1 
ATOM   8269  H HB   . ILE B 1 205 ? 2.031   42.804  47.310 1.00 10.63 ?  171  ILE B HB   1 
ATOM   8270  H HG12 . ILE B 1 205 ? 1.495   44.887  46.560 1.00 11.39 ?  171  ILE B HG12 1 
ATOM   8271  H HG13 . ILE B 1 205 ? 3.067   44.746  46.376 1.00 11.39 ?  171  ILE B HG13 1 
ATOM   8272  H HG21 . ILE B 1 205 ? 4.128   42.669  46.180 1.00 11.66 ?  171  ILE B HG21 1 
ATOM   8273  H HG22 . ILE B 1 205 ? 3.328   41.297  46.149 1.00 11.66 ?  171  ILE B HG22 1 
ATOM   8274  H HG23 . ILE B 1 205 ? 3.341   42.238  44.869 1.00 11.66 ?  171  ILE B HG23 1 
ATOM   8275  H HD11 . ILE B 1 205 ? 2.352   45.743  44.493 1.00 13.89 ?  171  ILE B HD11 1 
ATOM   8276  H HD12 . ILE B 1 205 ? 2.618   44.235  44.068 1.00 13.89 ?  171  ILE B HD12 1 
ATOM   8277  H HD13 . ILE B 1 205 ? 1.135   44.734  44.339 1.00 13.89 ?  171  ILE B HD13 1 
ATOM   8278  N N    . ASP B 1 206 ? 0.765   40.047  44.946 1.00 6.69  ?  172  ASP B N    1 
ATOM   8279  C CA   . ASP B 1 206 ? 0.604   38.607  45.031 1.00 8.15  ?  172  ASP B CA   1 
ATOM   8280  C C    . ASP B 1 206 ? 1.922   37.902  44.719 1.00 6.37  ?  172  ASP B C    1 
ATOM   8281  O O    . ASP B 1 206 ? 2.819   38.431  44.049 1.00 7.64  ?  172  ASP B O    1 
ATOM   8282  C CB   . ASP B 1 206 ? -0.498  38.141  44.069 1.00 7.58  ?  172  ASP B CB   1 
ATOM   8283  C CG   . ASP B 1 206 ? -0.917  36.715  44.310 1.00 7.66  ?  172  ASP B CG   1 
ATOM   8284  O OD1  . ASP B 1 206 ? -0.799  36.271  45.479 1.00 7.85  ?  172  ASP B OD1  1 
ATOM   8285  O OD2  . ASP B 1 206 ? -1.371  36.048  43.344 1.00 8.79  ?  172  ASP B OD2  1 
ATOM   8286  H H    . ASP B 1 206 ? 0.887   40.327  44.142 1.00 8.03  ?  172  ASP B H    1 
ATOM   8287  H HA   . ASP B 1 206 ? 0.349   38.356  45.933 1.00 9.78  ?  172  ASP B HA   1 
ATOM   8288  H HB2  . ASP B 1 206 ? -1.278  38.706  44.183 1.00 9.10  ?  172  ASP B HB2  1 
ATOM   8289  H HB3  . ASP B 1 206 ? -0.171  38.207  43.158 1.00 9.10  ?  172  ASP B HB3  1 
ATOM   8290  N N    . ALA B 1 207 ? 2.025   36.682  45.268 1.00 7.36  ?  173  ALA B N    1 
ATOM   8291  C CA   . ALA B 1 207 ? 3.087   35.702  45.042 1.00 8.26  ?  173  ALA B CA   1 
ATOM   8292  C C    . ALA B 1 207 ? 4.346   35.968  45.859 1.00 8.36  ?  173  ALA B C    1 
ATOM   8293  O O    . ALA B 1 207 ? 5.403   35.364  45.602 1.00 8.18  ?  173  ALA B O    1 
ATOM   8294  C CB   . ALA B 1 207 ? 3.404   35.467  43.564 1.00 9.40  ?  173  ALA B CB   1 
ATOM   8295  H H    . ALA B 1 207 ? 1.439   36.380  45.820 1.00 8.83  ?  173  ALA B H    1 
ATOM   8296  H HA   . ALA B 1 207 ? 2.749   34.851  45.360 1.00 9.91  ?  173  ALA B HA   1 
ATOM   8297  H HB1  . ALA B 1 207 ? 4.060   34.756  43.491 1.00 11.28 ?  173  ALA B HB1  1 
ATOM   8298  H HB2  . ALA B 1 207 ? 2.589   35.214  43.103 1.00 11.28 ?  173  ALA B HB2  1 
ATOM   8299  H HB3  . ALA B 1 207 ? 3.760   36.285  43.184 1.00 11.28 ?  173  ALA B HB3  1 
ATOM   8300  N N    . ASN B 1 208 ? 4.222   36.804  46.886 1.00 8.51  ?  174  ASN B N    1 
ATOM   8301  C CA   . ASN B 1 208 ? 5.297   36.990  47.847 1.00 8.45  ?  174  ASN B CA   1 
ATOM   8302  C C    . ASN B 1 208 ? 5.809   35.659  48.372 1.00 9.00  ?  174  ASN B C    1 
ATOM   8303  O O    . ASN B 1 208 ? 7.026   35.467  48.525 1.00 9.31  ?  174  ASN B O    1 
ATOM   8304  C CB   . ASN B 1 208 ? 4.790   37.829  49.017 1.00 9.66  ?  174  ASN B CB   1 
ATOM   8305  C CG   . ASN B 1 208 ? 4.004   39.038  48.560 1.00 8.09  ?  174  ASN B CG   1 
ATOM   8306  O OD1  . ASN B 1 208 ? 4.589   40.073  48.220 1.00 9.22  ?  174  ASN B OD1  1 
ATOM   8307  N ND2  . ASN B 1 208 ? 2.692   38.913  48.509 1.00 8.41  ?  174  ASN B ND2  1 
ATOM   8308  H H    . ASN B 1 208 ? 3.522   37.276  47.049 1.00 10.22 ?  174  ASN B H    1 
ATOM   8309  H HA   . ASN B 1 208 ? 6.030   37.453  47.411 1.00 10.13 ?  174  ASN B HA   1 
ATOM   8310  H HB2  . ASN B 1 208 ? 4.209   37.283  49.570 1.00 11.59 ?  174  ASN B HB2  1 
ATOM   8311  H HB3  . ASN B 1 208 ? 5.547   38.140  49.536 1.00 11.59 ?  174  ASN B HB3  1 
ATOM   8312  H HD21 . ASN B 1 208 ? 2.207   39.576  48.254 1.00 10.09 ?  174  ASN B HD21 1 
ATOM   8313  H HD22 . ASN B 1 208 ? 2.321   38.169  48.729 1.00 10.09 ?  174  ASN B HD22 1 
ATOM   8314  N N    . ILE B 1 209 ? 4.900   34.723  48.642 1.00 8.43  ?  175  ILE B N    1 
ATOM   8315  C CA   . ILE B 1 209 ? 5.283   33.482  49.305 1.00 8.60  ?  175  ILE B CA   1 
ATOM   8316  C C    . ILE B 1 209 ? 6.039   32.579  48.355 1.00 9.22  ?  175  ILE B C    1 
ATOM   8317  O O    . ILE B 1 209 ? 6.931   31.832  48.784 1.00 9.83  ?  175  ILE B O    1 
ATOM   8318  C CB   . ILE B 1 209 ? 4.031   32.846  49.916 1.00 8.87  ?  175  ILE B CB   1 
ATOM   8319  C CG1  . ILE B 1 209 ? 3.528   33.747  51.054 1.00 10.87 ?  175  ILE B CG1  1 
ATOM   8320  C CG2  . ILE B 1 209 ? 4.347   31.476  50.470 1.00 9.89  ?  175  ILE B CG2  1 
ATOM   8321  C CD1  . ILE B 1 209 ? 2.168   33.431  51.560 1.00 12.35 ?  175  ILE B CD1  1 
ATOM   8322  H H    . ILE B 1 209 ? 4.063   34.782  48.454 1.00 10.11 ?  175  ILE B H    1 
ATOM   8323  H HA   . ILE B 1 209 ? 5.898   33.659  50.034 1.00 10.32 ?  175  ILE B HA   1 
ATOM   8324  H HB   . ILE B 1 209 ? 3.354   32.756  49.227 1.00 10.65 ?  175  ILE B HB   1 
ATOM   8325  H HG12 . ILE B 1 209 ? 4.141   33.667  51.801 1.00 13.05 ?  175  ILE B HG12 1 
ATOM   8326  H HG13 . ILE B 1 209 ? 3.512   34.663  50.734 1.00 13.05 ?  175  ILE B HG13 1 
ATOM   8327  H HG21 . ILE B 1 209 ? 3.581   31.152  50.968 1.00 11.86 ?  175  ILE B HG21 1 
ATOM   8328  H HG22 . ILE B 1 209 ? 4.541   30.875  49.733 1.00 11.86 ?  175  ILE B HG22 1 
ATOM   8329  H HG23 . ILE B 1 209 ? 5.119   31.542  51.054 1.00 11.86 ?  175  ILE B HG23 1 
ATOM   8330  H HD11 . ILE B 1 209 ? 1.880   34.139  52.157 1.00 14.81 ?  175  ILE B HD11 1 
ATOM   8331  H HD12 . ILE B 1 209 ? 1.559   33.363  50.809 1.00 14.81 ?  175  ILE B HD12 1 
ATOM   8332  H HD13 . ILE B 1 209 ? 2.198   32.587  52.039 1.00 14.81 ?  175  ILE B HD13 1 
ATOM   8333  N N    . LYS B 1 210 ? 5.756   32.657  47.044 1.00 8.55  ?  176  LYS B N    1 
ATOM   8334  C CA   . LYS B 1 210 ? 6.543   31.918  46.062 1.00 9.13  ?  176  LYS B CA   1 
ATOM   8335  C C    . LYS B 1 210 ? 7.988   32.395  46.027 1.00 9.39  ?  176  LYS B C    1 
ATOM   8336  O O    . LYS B 1 210 ? 8.894   31.594  45.751 1.00 9.56  ?  176  LYS B O    1 
ATOM   8337  C CB   . LYS B 1 210 ? 5.902   32.035  44.677 1.00 8.53  ?  176  LYS B CB   1 
ATOM   8338  C CG   . LYS B 1 210 ? 4.677   31.161  44.539 1.00 9.21  ?  176  LYS B CG   1 
ATOM   8339  C CD   . LYS B 1 210 ? 3.949   31.379  43.242 1.00 8.66  ?  176  LYS B CD   1 
ATOM   8340  C CE   . LYS B 1 210 ? 2.877   30.322  42.985 1.00 10.64 ?  176  LYS B CE   1 
ATOM   8341  N NZ   . LYS B 1 210 ? 1.729   30.466  43.914 1.00 9.45  ?  176  LYS B NZ   1 
ATOM   8342  H H    . LYS B 1 210 ? 5.119   33.126  46.706 1.00 10.27 ?  176  LYS B H    1 
ATOM   8343  H HA   . LYS B 1 210 ? 6.549   30.980  46.308 1.00 10.95 ?  176  LYS B HA   1 
ATOM   8344  H HB2  . LYS B 1 210 ? 5.634   32.956  44.527 1.00 10.24 ?  176  LYS B HB2  1 
ATOM   8345  H HB3  . LYS B 1 210 ? 6.545   31.763  44.005 1.00 10.24 ?  176  LYS B HB3  1 
ATOM   8346  H HG2  . LYS B 1 210 ? 4.947   30.230  44.578 1.00 11.06 ?  176  LYS B HG2  1 
ATOM   8347  H HG3  . LYS B 1 210 ? 4.064   31.359  45.264 1.00 11.06 ?  176  LYS B HG3  1 
ATOM   8348  H HD2  . LYS B 1 210 ? 3.516   32.247  43.263 1.00 10.39 ?  176  LYS B HD2  1 
ATOM   8349  H HD3  . LYS B 1 210 ? 4.586   31.344  42.511 1.00 10.39 ?  176  LYS B HD3  1 
ATOM   8350  H HE2  . LYS B 1 210 ? 2.547   30.415  42.077 1.00 12.76 ?  176  LYS B HE2  1 
ATOM   8351  H HE3  . LYS B 1 210 ? 3.260   29.440  43.110 1.00 12.76 ?  176  LYS B HE3  1 
ATOM   8352  H HZ1  . LYS B 1 210 ? 1.362   31.272  43.822 1.00 11.34 ?  176  LYS B HZ1  1 
ATOM   8353  H HZ2  . LYS B 1 210 ? 1.114   29.848  43.736 1.00 11.34 ?  176  LYS B HZ2  1 
ATOM   8354  H HZ3  . LYS B 1 210 ? 2.003   30.367  44.755 1.00 11.34 ?  176  LYS B HZ3  1 
ATOM   8355  N N    . VAL B 1 211 ? 8.238   33.685  46.284 1.00 9.26  ?  177  VAL B N    1 
ATOM   8356  C CA   . VAL B 1 211 ? 9.620   34.162  46.386 1.00 10.02 ?  177  VAL B CA   1 
ATOM   8357  C C    . VAL B 1 211 ? 10.261  33.688  47.677 1.00 9.98  ?  177  VAL B C    1 
ATOM   8358  O O    . VAL B 1 211 ? 11.438  33.307  47.698 1.00 9.98  ?  177  VAL B O    1 
ATOM   8359  C CB   . VAL B 1 211 ? 9.638   35.698  46.337 1.00 9.46  ?  177  VAL B CB   1 
ATOM   8360  C CG1  . VAL B 1 211 ? 11.039  36.219  46.680 1.00 10.47 ?  177  VAL B CG1  1 
ATOM   8361  C CG2  . VAL B 1 211 ? 9.203   36.188  44.985 1.00 10.40 ?  177  VAL B CG2  1 
ATOM   8362  H H    . VAL B 1 211 ? 7.639   34.291  46.400 1.00 11.11 ?  177  VAL B H    1 
ATOM   8363  H HA   . VAL B 1 211 ? 10.119  33.799  45.638 1.00 12.03 ?  177  VAL B HA   1 
ATOM   8364  H HB   . VAL B 1 211 ? 9.013   36.045  46.994 1.00 11.35 ?  177  VAL B HB   1 
ATOM   8365  H HG11 . VAL B 1 211 ? 11.166  37.084  46.262 1.00 12.56 ?  177  VAL B HG11 1 
ATOM   8366  H HG12 . VAL B 1 211 ? 11.118  36.302  47.644 1.00 12.56 ?  177  VAL B HG12 1 
ATOM   8367  H HG13 . VAL B 1 211 ? 11.700  35.591  46.348 1.00 12.56 ?  177  VAL B HG13 1 
ATOM   8368  H HG21 . VAL B 1 211 ? 9.143   37.156  45.004 1.00 12.48 ?  177  VAL B HG21 1 
ATOM   8369  H HG22 . VAL B 1 211 ? 9.856   35.911  44.323 1.00 12.48 ?  177  VAL B HG22 1 
ATOM   8370  H HG23 . VAL B 1 211 ? 8.336   35.807  44.774 1.00 12.48 ?  177  VAL B HG23 1 
ATOM   8371  N N    . LEU B 1 212 ? 9.516   33.735  48.767 1.00 9.78  ?  178  LEU B N    1 
ATOM   8372  C CA   . LEU B 1 212 ? 10.090  33.644  50.108 1.00 10.76 ?  178  LEU B CA   1 
ATOM   8373  C C    . LEU B 1 212 ? 10.244  32.219  50.614 1.00 14.94 ?  178  LEU B C    1 
ATOM   8374  O O    . LEU B 1 212 ? 11.004  31.996  51.562 1.00 13.42 ?  178  LEU B O    1 
ATOM   8375  C CB   . LEU B 1 212 ? 9.264   34.472  51.092 1.00 9.80  ?  178  LEU B CB   1 
ATOM   8376  C CG   . LEU B 1 212 ? 9.311   35.976  50.813 1.00 10.08 ?  178  LEU B CG   1 
ATOM   8377  C CD1  . LEU B 1 212 ? 8.238   36.685  51.599 1.00 11.84 ?  178  LEU B CD1  1 
ATOM   8378  C CD2  . LEU B 1 212 ? 10.689  36.555  51.124 1.00 13.03 ?  178  LEU B CD2  1 
ATOM   8379  H H    . LEU B 1 212 ? 8.660   33.822  48.763 1.00 11.73 ?  178  LEU B H    1 
ATOM   8380  H HA   . LEU B 1 212 ? 10.982  34.024  50.088 1.00 12.91 ?  178  LEU B HA   1 
ATOM   8381  H HB2  . LEU B 1 212 ? 8.338   34.187  51.039 1.00 11.76 ?  178  LEU B HB2  1 
ATOM   8382  H HB3  . LEU B 1 212 ? 9.606   34.324  51.988 1.00 11.76 ?  178  LEU B HB3  1 
ATOM   8383  H HG   . LEU B 1 212 ? 9.144   36.125  49.870 1.00 12.10 ?  178  LEU B HG   1 
ATOM   8384  H HD11 . LEU B 1 212 ? 8.258   37.630  51.379 1.00 14.21 ?  178  LEU B HD11 1 
ATOM   8385  H HD12 . LEU B 1 212 ? 7.375   36.309  51.366 1.00 14.21 ?  178  LEU B HD12 1 
ATOM   8386  H HD13 . LEU B 1 212 ? 8.408   36.563  52.547 1.00 14.21 ?  178  LEU B HD13 1 
ATOM   8387  H HD21 . LEU B 1 212 ? 10.656  37.520  51.024 1.00 15.63 ?  178  LEU B HD21 1 
ATOM   8388  H HD22 . LEU B 1 212 ? 10.931  36.325  52.035 1.00 15.63 ?  178  LEU B HD22 1 
ATOM   8389  H HD23 . LEU B 1 212 ? 11.336  36.181  50.506 1.00 15.63 ?  178  LEU B HD23 1 
ATOM   8390  N N    . VAL B 1 213 ? 9.540   31.252  50.034 1.00 10.24 ?  179  VAL B N    1 
ATOM   8391  C CA   . VAL B 1 213 ? 9.745   29.838  50.340 1.00 11.50 ?  179  VAL B CA   1 
ATOM   8392  C C    . VAL B 1 213 ? 10.832  29.334  49.396 1.00 11.69 ?  179  VAL B C    1 
ATOM   8393  O O    . VAL B 1 213 ? 10.592  29.262  48.183 1.00 11.21 ?  179  VAL B O    1 
ATOM   8394  C CB   . VAL B 1 213 ? 8.444   29.052  50.154 1.00 10.75 ?  179  VAL B CB   1 
ATOM   8395  C CG1  . VAL B 1 213 ? 8.700   27.559  50.254 1.00 14.55 ?  179  VAL B CG1  1 
ATOM   8396  C CG2  . VAL B 1 213 ? 7.441   29.477  51.180 1.00 11.45 ?  179  VAL B CG2  1 
ATOM   8397  H H    . VAL B 1 213 ? 8.927   31.391  49.448 1.00 12.29 ?  179  VAL B H    1 
ATOM   8398  H HA   . VAL B 1 213 ? 10.048  29.727  51.255 1.00 13.80 ?  179  VAL B HA   1 
ATOM   8399  H HB   . VAL B 1 213 ? 8.088   29.237  49.271 1.00 12.91 ?  179  VAL B HB   1 
ATOM   8400  H HG11 . VAL B 1 213 ? 7.858   27.105  50.416 1.00 17.46 ?  179  VAL B HG11 1 
ATOM   8401  H HG12 . VAL B 1 213 ? 9.088   27.249  49.421 1.00 17.46 ?  179  VAL B HG12 1 
ATOM   8402  H HG13 . VAL B 1 213 ? 9.312   27.392  50.987 1.00 17.46 ?  179  VAL B HG13 1 
ATOM   8403  H HG21 . VAL B 1 213 ? 6.626   28.967  51.054 1.00 13.74 ?  179  VAL B HG21 1 
ATOM   8404  H HG22 . VAL B 1 213 ? 7.803   29.309  52.064 1.00 13.74 ?  179  VAL B HG22 1 
ATOM   8405  H HG23 . VAL B 1 213 ? 7.260   30.423  51.071 1.00 13.74 ?  179  VAL B HG23 1 
ATOM   8406  N N    . PRO B 1 214 ? 12.044  29.044  49.877 1.00 11.84 ?  180  PRO B N    1 
ATOM   8407  C CA   . PRO B 1 214 ? 13.145  28.846  48.925 1.00 13.73 ?  180  PRO B CA   1 
ATOM   8408  C C    . PRO B 1 214 ? 12.921  27.739  47.911 1.00 10.88 ?  180  PRO B C    1 
ATOM   8409  O O    . PRO B 1 214 ? 13.381  27.854  46.772 1.00 11.39 ?  180  PRO B O    1 
ATOM   8410  C CB   . PRO B 1 214 ? 14.356  28.591  49.837 1.00 13.28 ?  180  PRO B CB   1 
ATOM   8411  C CG   . PRO B 1 214 ? 14.003  29.320  51.093 1.00 16.55 ?  180  PRO B CG   1 
ATOM   8412  C CD   . PRO B 1 214 ? 12.530  29.146  51.270 1.00 12.66 ?  180  PRO B CD   1 
ATOM   8413  H HA   . PRO B 1 214 ? 13.294  29.667  48.431 1.00 16.48 ?  180  PRO B HA   1 
ATOM   8414  H HB2  . PRO B 1 214 ? 14.462  27.640  49.999 1.00 15.93 ?  180  PRO B HB2  1 
ATOM   8415  H HB3  . PRO B 1 214 ? 15.162  28.951  49.435 1.00 15.93 ?  180  PRO B HB3  1 
ATOM   8416  H HG2  . PRO B 1 214 ? 14.486  28.935  51.841 1.00 19.86 ?  180  PRO B HG2  1 
ATOM   8417  H HG3  . PRO B 1 214 ? 14.229  30.259  51.001 1.00 19.86 ?  180  PRO B HG3  1 
ATOM   8418  H HD2  . PRO B 1 214 ? 12.333  28.336  51.767 1.00 15.19 ?  180  PRO B HD2  1 
ATOM   8419  H HD3  . PRO B 1 214 ? 12.141  29.913  51.718 1.00 15.19 ?  180  PRO B HD3  1 
ATOM   8420  N N    . SER B 1 215 ? 12.245  26.655  48.295 1.00 12.34 ?  181  SER B N    1 
ATOM   8421  C CA   . SER B 1 215 ? 12.127  25.537  47.372 1.00 12.82 ?  181  SER B CA   1 
ATOM   8422  C C    . SER B 1 215 ? 11.306  25.871  46.135 1.00 11.98 ?  181  SER B C    1 
ATOM   8423  O O    . SER B 1 215 ? 11.494  25.216  45.109 1.00 12.32 ?  181  SER B O    1 
ATOM   8424  C CB   . SER B 1 215 ? 11.515  24.316  48.061 1.00 13.21 ?  181  SER B CB   1 
ATOM   8425  O OG   . SER B 1 215 ? 10.147  24.515  48.337 1.00 13.61 ?  181  SER B OG   1 
ATOM   8426  H H    . SER B 1 215 ? 11.860  26.550  49.057 1.00 14.81 ?  181  SER B H    1 
ATOM   8427  H HA   . SER B 1 215 ? 13.026  25.304  47.089 1.00 15.38 ?  181  SER B HA   1 
ATOM   8428  H HB2  . SER B 1 215 ? 11.608  23.547  47.478 1.00 15.85 ?  181  SER B HB2  1 
ATOM   8429  H HB3  . SER B 1 215 ? 11.983  24.159  48.896 1.00 15.85 ?  181  SER B HB3  1 
ATOM   8430  H HG   . SER B 1 215 ? 9.856   23.888  48.814 1.00 16.33 ?  181  SER B HG   1 
ATOM   8431  N N    . PHE B 1 216 ? 10.413  26.873  46.193 1.00 10.78 ?  182  PHE B N    1 
ATOM   8432  C CA   . PHE B 1 216 ? 9.572   27.137  45.030 1.00 11.00 ?  182  PHE B CA   1 
ATOM   8433  C C    . PHE B 1 216 ? 10.423  27.445  43.804 1.00 10.29 ?  182  PHE B C    1 
ATOM   8434  O O    . PHE B 1 216 ? 10.260  26.829  42.751 1.00 10.71 ?  182  PHE B O    1 
ATOM   8435  C CB   . PHE B 1 216 ? 8.545   28.248  45.272 1.00 10.55 ?  182  PHE B CB   1 
ATOM   8436  C CG   . PHE B 1 216 ? 7.626   28.420  44.108 1.00 9.46  ?  182  PHE B CG   1 
ATOM   8437  C CD1  . PHE B 1 216 ? 6.501   27.624  43.976 1.00 10.93 ?  182  PHE B CD1  1 
ATOM   8438  C CD2  . PHE B 1 216 ? 7.922   29.317  43.097 1.00 11.00 ?  182  PHE B CD2  1 
ATOM   8439  C CE1  . PHE B 1 216 ? 5.675   27.741  42.877 1.00 11.47 ?  182  PHE B CE1  1 
ATOM   8440  C CE2  . PHE B 1 216 ? 7.090   29.433  41.990 1.00 11.33 ?  182  PHE B CE2  1 
ATOM   8441  C CZ   . PHE B 1 216 ? 5.968   28.639  41.890 1.00 11.47 ?  182  PHE B CZ   1 
ATOM   8442  H H    . PHE B 1 216 ? 10.285  27.390  46.868 1.00 12.93 ?  182  PHE B H    1 
ATOM   8443  H HA   . PHE B 1 216 ? 9.055   26.333  44.868 1.00 13.20 ?  182  PHE B HA   1 
ATOM   8444  H HB2  . PHE B 1 216 ? 8.011   28.025  46.050 1.00 12.66 ?  182  PHE B HB2  1 
ATOM   8445  H HB3  . PHE B 1 216 ? 9.011   29.086  45.419 1.00 12.66 ?  182  PHE B HB3  1 
ATOM   8446  H HD1  . PHE B 1 216 ? 6.298   27.003  44.638 1.00 13.12 ?  182  PHE B HD1  1 
ATOM   8447  H HD2  . PHE B 1 216 ? 8.684   29.847  43.158 1.00 13.20 ?  182  PHE B HD2  1 
ATOM   8448  H HE1  . PHE B 1 216 ? 4.917   27.206  42.807 1.00 13.77 ?  182  PHE B HE1  1 
ATOM   8449  H HE2  . PHE B 1 216 ? 7.290   30.044  41.318 1.00 13.59 ?  182  PHE B HE2  1 
ATOM   8450  H HZ   . PHE B 1 216 ? 5.410   28.715  41.150 1.00 13.77 ?  182  PHE B HZ   1 
ATOM   8451  N N    . PHE B 1 217 ? 11.340  28.417  43.913 1.00 9.97  ?  183  PHE B N    1 
ATOM   8452  C CA   . PHE B 1 217 ? 12.220  28.707  42.785 1.00 9.96  ?  183  PHE B CA   1 
ATOM   8453  C C    . PHE B 1 217 ? 13.514  27.890  42.770 1.00 10.11 ?  183  PHE B C    1 
ATOM   8454  O O    . PHE B 1 217 ? 14.047  27.642  41.692 1.00 12.08 ?  183  PHE B O    1 
ATOM   8455  C CB   . PHE B 1 217 ? 12.537  30.209  42.709 1.00 9.45  ?  183  PHE B CB   1 
ATOM   8456  C CG   . PHE B 1 217 ? 11.404  31.026  42.153 1.00 9.18  ?  183  PHE B CG   1 
ATOM   8457  C CD1  . PHE B 1 217 ? 10.945  30.809  40.878 1.00 9.73  ?  183  PHE B CD1  1 
ATOM   8458  C CD2  . PHE B 1 217 ? 10.776  31.988  42.930 1.00 10.79 ?  183  PHE B CD2  1 
ATOM   8459  C CE1  . PHE B 1 217 ? 9.890   31.547  40.353 1.00 9.94  ?  183  PHE B CE1  1 
ATOM   8460  C CE2  . PHE B 1 217 ? 9.719   32.736  42.406 1.00 11.47 ?  183  PHE B CE2  1 
ATOM   8461  C CZ   . PHE B 1 217 ? 9.273   32.507  41.128 1.00 9.52  ?  183  PHE B CZ   1 
ATOM   8462  H H    . PHE B 1 217 ? 11.465  28.905  44.610 1.00 11.96 ?  183  PHE B H    1 
ATOM   8463  H HA   . PHE B 1 217 ? 11.740  28.474  41.975 1.00 11.95 ?  183  PHE B HA   1 
ATOM   8464  H HB2  . PHE B 1 217 ? 12.729  30.535  43.602 1.00 11.34 ?  183  PHE B HB2  1 
ATOM   8465  H HB3  . PHE B 1 217 ? 13.308  30.339  42.135 1.00 11.34 ?  183  PHE B HB3  1 
ATOM   8466  H HD1  . PHE B 1 217 ? 11.349  30.154  40.355 1.00 11.68 ?  183  PHE B HD1  1 
ATOM   8467  H HD2  . PHE B 1 217 ? 11.060  32.136  43.803 1.00 12.94 ?  183  PHE B HD2  1 
ATOM   8468  H HE1  . PHE B 1 217 ? 9.602   31.393  39.483 1.00 11.93 ?  183  PHE B HE1  1 
ATOM   8469  H HE2  . PHE B 1 217 ? 9.315   33.393  42.926 1.00 13.77 ?  183  PHE B HE2  1 
ATOM   8470  H HZ   . PHE B 1 217 ? 8.560   32.996  40.786 1.00 11.43 ?  183  PHE B HZ   1 
ATOM   8471  N N    A SER B 1 218 ? 14.045  27.499  43.928 0.72 12.71 ?  184  SER B N    1 
ATOM   8472  N N    B SER B 1 218 ? 14.040  27.499  43.934 0.28 12.75 ?  184  SER B N    1 
ATOM   8473  C CA   A SER B 1 218 ? 15.293  26.729  43.874 0.72 13.02 ?  184  SER B CA   1 
ATOM   8474  C CA   B SER B 1 218 ? 15.264  26.699  43.936 0.28 13.09 ?  184  SER B CA   1 
ATOM   8475  C C    A SER B 1 218 ? 15.113  25.433  43.091 0.72 14.79 ?  184  SER B C    1 
ATOM   8476  C C    B SER B 1 218 ? 15.094  25.453  43.080 0.28 14.80 ?  184  SER B C    1 
ATOM   8477  O O    A SER B 1 218 ? 16.025  25.021  42.362 0.72 14.41 ?  184  SER B O    1 
ATOM   8478  O O    B SER B 1 218 ? 15.995  25.077  42.319 0.28 14.36 ?  184  SER B O    1 
ATOM   8479  C CB   A SER B 1 218 ? 15.845  26.468  45.273 0.72 15.91 ?  184  SER B CB   1 
ATOM   8480  C CB   B SER B 1 218 ? 15.629  26.294  45.362 0.28 14.93 ?  184  SER B CB   1 
ATOM   8481  O OG   A SER B 1 218 ? 15.139  25.451  45.945 0.72 15.32 ?  184  SER B OG   1 
ATOM   8482  O OG   B SER B 1 218 ? 16.203  27.384  46.059 0.28 15.23 ?  184  SER B OG   1 
ATOM   8483  H H    A SER B 1 218 ? 13.726  27.655  44.711 0.72 15.26 ?  184  SER B H    1 
ATOM   8484  H H    B SER B 1 218 ? 13.718  27.680  44.711 0.28 15.30 ?  184  SER B H    1 
ATOM   8485  H HA   A SER B 1 218 ? 15.962  27.261  43.415 0.72 15.62 ?  184  SER B HA   1 
ATOM   8486  H HA   B SER B 1 218 ? 15.987  27.236  43.577 0.28 15.70 ?  184  SER B HA   1 
ATOM   8487  H HB2  A SER B 1 218 ? 16.774  26.200  45.194 0.72 19.09 ?  184  SER B HB2  1 
ATOM   8488  H HB2  B SER B 1 218 ? 14.827  26.009  45.826 0.28 17.91 ?  184  SER B HB2  1 
ATOM   8489  H HB3  A SER B 1 218 ? 15.779  27.286  45.790 0.72 19.09 ?  184  SER B HB3  1 
ATOM   8490  H HB3  B SER B 1 218 ? 16.270  25.566  45.330 0.28 17.91 ?  184  SER B HB3  1 
ATOM   8491  H HG   A SER B 1 218 ? 15.142  25.599  46.772 0.72 18.38 ?  184  SER B HG   1 
ATOM   8492  H HG   B SER B 1 218 ? 16.712  27.815  45.548 0.28 18.28 ?  184  SER B HG   1 
ATOM   8493  N N    . SER B 1 219 ? 13.928  24.816  43.178 1.00 14.08 ?  185  SER B N    1 
ATOM   8494  C CA   . SER B 1 219 ? 13.646  23.593  42.429 1.00 13.11 ?  185  SER B CA   1 
ATOM   8495  C C    . SER B 1 219 ? 13.518  23.831  40.934 1.00 14.37 ?  185  SER B C    1 
ATOM   8496  O O    . SER B 1 219 ? 13.518  22.864  40.167 1.00 17.33 ?  185  SER B O    1 
ATOM   8497  C CB   . SER B 1 219 ? 12.370  22.965  42.965 1.00 14.47 ?  185  SER B CB   1 
ATOM   8498  O OG   . SER B 1 219 ? 11.243  23.799  42.713 1.00 15.84 ?  185  SER B OG   1 
ATOM   8499  H H    . SER B 1 219 ? 13.274  25.090  43.664 1.00 16.89 ?  185  SER B H    1 
ATOM   8500  H HA   . SER B 1 219 ? 14.374  22.966  42.557 1.00 15.73 ?  185  SER B HA   1 
ATOM   8501  H HB2  . SER B 1 219 ? 12.232  22.110  42.528 1.00 17.37 ?  185  SER B HB2  1 
ATOM   8502  H HB3  . SER B 1 219 ? 12.459  22.838  43.922 1.00 17.37 ?  185  SER B HB3  1 
ATOM   8503  H HG   . SER B 1 219 ? 10.746  23.822  43.390 1.00 19.01 ?  185  SER B HG   1 
ATOM   8504  N N    . LYS B 1 220 ? 13.405  25.084  40.496 1.00 11.45 ?  186  LYS B N    1 
ATOM   8505  C CA   . LYS B 1 220 ? 13.241  25.430  39.097 1.00 12.31 ?  186  LYS B CA   1 
ATOM   8506  C C    . LYS B 1 220 ? 14.514  25.991  38.472 1.00 12.51 ?  186  LYS B C    1 
ATOM   8507  O O    . LYS B 1 220 ? 14.824  25.688  37.319 1.00 14.13 ?  186  LYS B O    1 
ATOM   8508  C CB   . LYS B 1 220 ? 12.106  26.470  38.959 1.00 13.29 ?  186  LYS B CB   1 
ATOM   8509  C CG   . LYS B 1 220 ? 10.718  25.955  39.379 1.00 12.27 ?  186  LYS B CG   1 
ATOM   8510  C CD   . LYS B 1 220 ? 9.691   27.094  39.341 1.00 13.14 ?  186  LYS B CD   1 
ATOM   8511  C CE   . LYS B 1 220 ? 8.272   26.589  39.562 1.00 14.52 ?  186  LYS B CE   1 
ATOM   8512  N NZ   . LYS B 1 220 ? 8.081   26.105  40.947 1.00 14.66 ?  186  LYS B NZ   1 
ATOM   8513  H H    . LYS B 1 220 ? 13.421  25.771  41.013 1.00 13.74 ?  186  LYS B H    1 
ATOM   8514  H HA   . LYS B 1 220 ? 12.994  24.636  38.597 1.00 14.77 ?  186  LYS B HA   1 
ATOM   8515  H HB2  . LYS B 1 220 ? 12.317  27.234  39.518 1.00 15.95 ?  186  LYS B HB2  1 
ATOM   8516  H HB3  . LYS B 1 220 ? 12.049  26.744  38.031 1.00 15.95 ?  186  LYS B HB3  1 
ATOM   8517  H HG2  . LYS B 1 220 ? 10.431  25.259  38.768 1.00 14.73 ?  186  LYS B HG2  1 
ATOM   8518  H HG3  . LYS B 1 220 ? 10.761  25.606  40.283 1.00 14.73 ?  186  LYS B HG3  1 
ATOM   8519  H HD2  . LYS B 1 220 ? 9.897   27.734  40.041 1.00 15.77 ?  186  LYS B HD2  1 
ATOM   8520  H HD3  . LYS B 1 220 ? 9.726   27.528  38.474 1.00 15.77 ?  186  LYS B HD3  1 
ATOM   8521  H HE2  . LYS B 1 220 ? 7.645   27.312  39.402 1.00 17.43 ?  186  LYS B HE2  1 
ATOM   8522  H HE3  . LYS B 1 220 ? 8.094   25.855  38.955 1.00 17.43 ?  186  LYS B HE3  1 
ATOM   8523  H HZ1  . LYS B 1 220 ? 7.217   25.958  41.101 1.00 17.59 ?  186  LYS B HZ1  1 
ATOM   8524  H HZ2  . LYS B 1 220 ? 8.530   25.346  41.068 1.00 17.59 ?  186  LYS B HZ2  1 
ATOM   8525  H HZ3  . LYS B 1 220 ? 8.379   26.712  41.526 1.00 17.59 ?  186  LYS B HZ3  1 
ATOM   8526  N N    . VAL B 1 221 ? 15.234  26.853  39.193 1.00 13.32 ?  187  VAL B N    1 
ATOM   8527  C CA   . VAL B 1 221 ? 16.309  27.640  38.603 1.00 14.95 ?  187  VAL B CA   1 
ATOM   8528  C C    . VAL B 1 221 ? 17.595  27.575  39.399 1.00 17.01 ?  187  VAL B C    1 
ATOM   8529  O O    . VAL B 1 221 ? 18.563  28.250  39.038 1.00 17.36 ?  187  VAL B O    1 
ATOM   8530  C CB   . VAL B 1 221 ? 15.893  29.108  38.363 1.00 13.68 ?  187  VAL B CB   1 
ATOM   8531  C CG1  . VAL B 1 221 ? 14.826  29.172  37.305 1.00 15.67 ?  187  VAL B CG1  1 
ATOM   8532  C CG2  . VAL B 1 221 ? 15.440  29.788  39.668 1.00 12.07 ?  187  VAL B CG2  1 
ATOM   8533  H H    . VAL B 1 221 ? 15.116  26.998  40.033 1.00 15.98 ?  187  VAL B H    1 
ATOM   8534  H HA   . VAL B 1 221 ? 16.506  27.261  37.732 1.00 17.94 ?  187  VAL B HA   1 
ATOM   8535  H HB   . VAL B 1 221 ? 16.663  29.606  38.047 1.00 16.42 ?  187  VAL B HB   1 
ATOM   8536  H HG11 . VAL B 1 221 ? 14.609  30.101  37.130 1.00 18.81 ?  187  VAL B HG11 1 
ATOM   8537  H HG12 . VAL B 1 221 ? 15.158  28.752  36.496 1.00 18.81 ?  187  VAL B HG12 1 
ATOM   8538  H HG13 . VAL B 1 221 ? 14.038  28.703  37.622 1.00 18.81 ?  187  VAL B HG13 1 
ATOM   8539  H HG21 . VAL B 1 221 ? 15.540  30.749  39.575 1.00 14.49 ?  187  VAL B HG21 1 
ATOM   8540  H HG22 . VAL B 1 221 ? 14.510  29.567  39.834 1.00 14.49 ?  187  VAL B HG22 1 
ATOM   8541  H HG23 . VAL B 1 221 ? 15.991  29.468  40.399 1.00 14.49 ?  187  VAL B HG23 1 
ATOM   8542  N N    . GLY B 1 222 ? 17.629  26.799  40.463 1.00 15.00 ?  188  GLY B N    1 
ATOM   8543  C CA   . GLY B 1 222 ? 18.842  26.591  41.219 1.00 16.11 ?  188  GLY B CA   1 
ATOM   8544  C C    . GLY B 1 222 ? 18.902  27.505  42.427 1.00 17.08 ?  188  GLY B C    1 
ATOM   8545  O O    . GLY B 1 222 ? 18.208  28.529  42.515 1.00 17.41 ?  188  GLY B O    1 
ATOM   8546  H H    . GLY B 1 222 ? 16.948  26.373  40.773 1.00 18.00 ?  188  GLY B H    1 
ATOM   8547  H HA2  . GLY B 1 222 ? 18.882  25.671  41.524 1.00 19.33 ?  188  GLY B HA2  1 
ATOM   8548  H HA3  . GLY B 1 222 ? 19.611  26.771  40.656 1.00 19.33 ?  188  GLY B HA3  1 
ATOM   8549  N N    . VAL B 1 223 ? 19.756  27.123  43.380 1.00 19.04 ?  189  VAL B N    1 
ATOM   8550  C CA   . VAL B 1 223 ? 19.764  27.798  44.673 1.00 19.52 ?  189  VAL B CA   1 
ATOM   8551  C C    . VAL B 1 223 ? 20.313  29.216  44.553 1.00 17.17 ?  189  VAL B C    1 
ATOM   8552  O O    . VAL B 1 223 ? 19.813  30.134  45.221 1.00 17.84 ?  189  VAL B O    1 
ATOM   8553  C CB   . VAL B 1 223 ? 20.522  26.982  45.742 1.00 17.06 ?  189  VAL B CB   1 
ATOM   8554  C CG1  . VAL B 1 223 ? 19.747  25.715  46.066 1.00 18.28 ?  189  VAL B CG1  1 
ATOM   8555  C CG2  . VAL B 1 223 ? 21.963  26.662  45.288 1.00 20.10 ?  189  VAL B CG2  1 
ATOM   8556  H H    . VAL B 1 223 ? 20.330  26.486  43.302 1.00 22.85 ?  189  VAL B H    1 
ATOM   8557  H HA   . VAL B 1 223 ? 18.841  27.861  44.964 1.00 23.42 ?  189  VAL B HA   1 
ATOM   8558  H HB   . VAL B 1 223 ? 20.596  27.511  46.552 1.00 20.47 ?  189  VAL B HB   1 
ATOM   8559  H HG11 . VAL B 1 223 ? 20.133  25.301  46.853 1.00 21.93 ?  189  VAL B HG11 1 
ATOM   8560  H HG12 . VAL B 1 223 ? 18.820  25.947  46.234 1.00 21.93 ?  189  VAL B HG12 1 
ATOM   8561  H HG13 . VAL B 1 223 ? 19.804  25.108  45.311 1.00 21.93 ?  189  VAL B HG13 1 
ATOM   8562  H HG21 . VAL B 1 223 ? 22.423  26.195  46.003 1.00 24.12 ?  189  VAL B HG21 1 
ATOM   8563  H HG22 . VAL B 1 223 ? 21.927  26.102  44.496 1.00 24.12 ?  189  VAL B HG22 1 
ATOM   8564  H HG23 . VAL B 1 223 ? 22.422  27.492  45.086 1.00 24.12 ?  189  VAL B HG23 1 
ATOM   8565  N N    . ASN B 1 224 ? 21.330  29.434  43.701 1.00 17.49 ?  190  ASN B N    1 
ATOM   8566  C CA   . ASN B 1 224 ? 21.882  30.787  43.593 1.00 19.43 ?  190  ASN B CA   1 
ATOM   8567  C C    . ASN B 1 224 ? 20.835  31.744  43.056 1.00 20.01 ?  190  ASN B C    1 
ATOM   8568  O O    . ASN B 1 224 ? 20.687  32.873  43.539 1.00 18.27 ?  190  ASN B O    1 
ATOM   8569  C CB   . ASN B 1 224 ? 23.103  30.823  42.668 1.00 21.16 ?  190  ASN B CB   1 
ATOM   8570  C CG   . ASN B 1 224 ? 24.298  30.004  43.162 1.00 17.05 ?  190  ASN B CG   1 
ATOM   8571  O OD1  . ASN B 1 224 ? 24.401  29.546  44.330 1.00 19.86 ?  190  ASN B OD1  1 
ATOM   8572  N ND2  . ASN B 1 224 ? 25.191  29.740  42.212 1.00 17.51 ?  190  ASN B ND2  1 
ATOM   8573  H H    . ASN B 1 224 ? 21.700  28.841  43.200 1.00 20.99 ?  190  ASN B H    1 
ATOM   8574  H HA   . ASN B 1 224 ? 22.167  31.062  44.478 1.00 23.32 ?  190  ASN B HA   1 
ATOM   8575  H HB2  . ASN B 1 224 ? 22.845  30.470  41.802 1.00 25.39 ?  190  ASN B HB2  1 
ATOM   8576  H HB3  . ASN B 1 224 ? 23.396  31.743  42.578 1.00 25.39 ?  190  ASN B HB3  1 
ATOM   8577  H HD21 . ASN B 1 224 ? 25.063  30.025  41.411 1.00 21.02 ?  190  ASN B HD21 1 
ATOM   8578  H HD22 . ASN B 1 224 ? 25.896  29.284  42.399 1.00 21.02 ?  190  ASN B HD22 1 
ATOM   8579  N N    . LYS B 1 225 ? 20.092  31.308  42.046 1.00 17.00 ?  191  LYS B N    1 
ATOM   8580  C CA   . LYS B 1 225 ? 19.101  32.188  41.445 1.00 15.07 ?  191  LYS B CA   1 
ATOM   8581  C C    . LYS B 1 225 ? 17.961  32.496  42.413 1.00 15.55 ?  191  LYS B C    1 
ATOM   8582  O O    . LYS B 1 225 ? 17.488  33.639  42.454 1.00 13.68 ?  191  LYS B O    1 
ATOM   8583  C CB   . LYS B 1 225 ? 18.605  31.581  40.136 1.00 18.61 ?  191  LYS B CB   1 
ATOM   8584  C CG   . LYS B 1 225 ? 17.771  32.502  39.305 1.00 16.95 ?  191  LYS B CG   1 
ATOM   8585  C CD   . LYS B 1 225 ? 18.615  33.623  38.713 1.00 21.16 ?  191  LYS B CD   1 
ATOM   8586  C CE   . LYS B 1 225 ? 17.850  34.415  37.671 1.00 20.11 ?  191  LYS B CE   1 
ATOM   8587  N NZ   . LYS B 1 225 ? 18.711  35.365  36.909 1.00 18.36 ?  191  LYS B NZ   1 
ATOM   8588  H H    . LYS B 1 225 ? 20.141  30.524  41.697 1.00 20.41 ?  191  LYS B H    1 
ATOM   8589  H HA   . LYS B 1 225 ? 19.512  33.039  41.228 1.00 18.09 ?  191  LYS B HA   1 
ATOM   8590  H HB2  . LYS B 1 225 ? 19.374  31.322  39.604 1.00 22.33 ?  191  LYS B HB2  1 
ATOM   8591  H HB3  . LYS B 1 225 ? 18.066  30.801  40.341 1.00 22.33 ?  191  LYS B HB3  1 
ATOM   8592  H HG2  . LYS B 1 225 ? 17.368  32.004  38.577 1.00 20.34 ?  191  LYS B HG2  1 
ATOM   8593  H HG3  . LYS B 1 225 ? 17.079  32.898  39.858 1.00 20.34 ?  191  LYS B HG3  1 
ATOM   8594  H HD2  . LYS B 1 225 ? 18.882  34.231  39.420 1.00 25.39 ?  191  LYS B HD2  1 
ATOM   8595  H HD3  . LYS B 1 225 ? 19.400  33.243  38.289 1.00 25.39 ?  191  LYS B HD3  1 
ATOM   8596  H HE2  . LYS B 1 225 ? 17.453  33.799  37.036 1.00 24.14 ?  191  LYS B HE2  1 
ATOM   8597  H HE3  . LYS B 1 225 ? 17.157  34.930  38.113 1.00 24.14 ?  191  LYS B HE3  1 
ATOM   8598  H HZ1  . LYS B 1 225 ? 19.028  35.993  37.455 1.00 22.03 ?  191  LYS B HZ1  1 
ATOM   8599  H HZ2  . LYS B 1 225 ? 19.395  34.929  36.543 1.00 22.03 ?  191  LYS B HZ2  1 
ATOM   8600  H HZ3  . LYS B 1 225 ? 18.238  35.754  36.264 1.00 22.03 ?  191  LYS B HZ3  1 
ATOM   8601  N N    . GLN B 1 226 ? 17.524  31.529  43.224 1.00 12.90 ?  192  GLN B N    1 
ATOM   8602  C CA   . GLN B 1 226 ? 16.466  31.830  44.187 1.00 11.97 ?  192  GLN B CA   1 
ATOM   8603  C C    . GLN B 1 226 ? 16.914  32.890  45.171 1.00 15.99 ?  192  GLN B C    1 
ATOM   8604  O O    . GLN B 1 226 ? 16.142  33.783  45.530 1.00 13.42 ?  192  GLN B O    1 
ATOM   8605  C CB   . GLN B 1 226 ? 16.013  30.571  44.935 1.00 13.16 ?  192  GLN B CB   1 
ATOM   8606  C CG   . GLN B 1 226 ? 14.798  30.773  45.876 1.00 12.47 ?  192  GLN B CG   1 
ATOM   8607  C CD   . GLN B 1 226 ? 15.134  31.471  47.180 1.00 17.48 ?  192  GLN B CD   1 
ATOM   8608  O OE1  . GLN B 1 226 ? 16.253  31.348  47.689 1.00 15.37 ?  192  GLN B OE1  1 
ATOM   8609  N NE2  . GLN B 1 226 ? 14.159  32.163  47.764 1.00 14.43 ?  192  GLN B NE2  1 
ATOM   8610  H H    . GLN B 1 226 ? 17.814  30.719  43.236 1.00 15.48 ?  192  GLN B H    1 
ATOM   8611  H HA   . GLN B 1 226 ? 15.700  32.161  43.693 1.00 14.36 ?  192  GLN B HA   1 
ATOM   8612  H HB2  . GLN B 1 226 ? 15.767  29.897  44.282 1.00 15.80 ?  192  GLN B HB2  1 
ATOM   8613  H HB3  . GLN B 1 226 ? 16.752  30.253  45.478 1.00 15.80 ?  192  GLN B HB3  1 
ATOM   8614  H HG2  . GLN B 1 226 ? 14.135  31.313  45.416 1.00 14.97 ?  192  GLN B HG2  1 
ATOM   8615  H HG3  . GLN B 1 226 ? 14.425  29.905  46.094 1.00 14.97 ?  192  GLN B HG3  1 
ATOM   8616  H HE21 . GLN B 1 226 ? 13.381  32.199  47.400 1.00 17.31 ?  192  GLN B HE21 1 
ATOM   8617  H HE22 . GLN B 1 226 ? 14.307  32.573  48.505 1.00 17.31 ?  192  GLN B HE22 1 
ATOM   8618  N N    . ALA B 1 227 ? 18.161  32.804  45.635 1.00 16.10 ?  193  ALA B N    1 
ATOM   8619  C CA   . ALA B 1 227 ? 18.631  33.778  46.609 1.00 14.70 ?  193  ALA B CA   1 
ATOM   8620  C C    . ALA B 1 227 ? 18.641  35.167  46.003 1.00 12.66 ?  193  ALA B C    1 
ATOM   8621  O O    . ALA B 1 227 ? 18.311  36.152  46.680 1.00 13.77 ?  193  ALA B O    1 
ATOM   8622  C CB   . ALA B 1 227 ? 20.042  33.400  47.054 1.00 17.01 ?  193  ALA B CB   1 
ATOM   8623  H H    . ALA B 1 227 ? 18.736  32.208  45.407 1.00 19.33 ?  193  ALA B H    1 
ATOM   8624  H HA   . ALA B 1 227 ? 18.045  33.776  47.382 1.00 17.64 ?  193  ALA B HA   1 
ATOM   8625  H HB1  . ALA B 1 227 ? 20.337  34.025  47.735 1.00 20.41 ?  193  ALA B HB1  1 
ATOM   8626  H HB2  . ALA B 1 227 ? 20.029  32.500  47.414 1.00 20.41 ?  193  ALA B HB2  1 
ATOM   8627  H HB3  . ALA B 1 227 ? 20.637  33.441  46.288 1.00 20.41 ?  193  ALA B HB3  1 
ATOM   8628  N N    . GLU B 1 228 ? 18.996  35.251  44.732 1.00 12.81 ?  194  GLU B N    1 
ATOM   8629  C CA   . GLU B 1 228 ? 19.033  36.520  44.025 1.00 13.56 ?  194  GLU B CA   1 
ATOM   8630  C C    . GLU B 1 228 ? 17.617  37.052  43.795 1.00 15.40 ?  194  GLU B C    1 
ATOM   8631  O O    . GLU B 1 228 ? 17.377  38.263  43.907 1.00 12.50 ?  194  GLU B O    1 
ATOM   8632  C CB   . GLU B 1 228 ? 19.738  36.303  42.690 1.00 15.43 ?  194  GLU B CB   1 
ATOM   8633  C CG   . GLU B 1 228 ? 21.257  36.196  42.800 1.00 17.89 ?  194  GLU B CG   1 
ATOM   8634  C CD   . GLU B 1 228 ? 21.848  35.272  41.754 1.00 31.11 ?  194  GLU B CD   1 
ATOM   8635  H H    . GLU B 1 228 ? 19.224  34.579  44.246 1.00 15.38 ?  194  GLU B H    1 
ATOM   8636  H HA   . GLU B 1 228 ? 19.522  37.179  44.542 1.00 16.28 ?  194  GLU B HA   1 
ATOM   8637  H HB2  . GLU B 1 228 ? 19.411  35.478  42.297 1.00 18.52 ?  194  GLU B HB2  1 
ATOM   8638  H HB3  . GLU B 1 228 ? 19.536  37.051  42.106 1.00 18.52 ?  194  GLU B HB3  1 
ATOM   8639  H HG2  . GLU B 1 228 ? 21.646  37.076  42.680 1.00 21.46 ?  194  GLU B HG2  1 
ATOM   8640  H HG3  . GLU B 1 228 ? 21.488  35.847  43.675 1.00 21.46 ?  194  GLU B HG3  1 
ATOM   8641  N N    . ILE B 1 229 ? 16.668  36.168  43.465 1.00 12.76 ?  195  ILE B N    1 
ATOM   8642  C CA   . ILE B 1 229 ? 15.266  36.572  43.314 1.00 11.07 ?  195  ILE B CA   1 
ATOM   8643  C C    . ILE B 1 229 ? 14.763  37.176  44.617 1.00 11.33 ?  195  ILE B C    1 
ATOM   8644  O O    . ILE B 1 229 ? 14.138  38.239  44.631 1.00 11.17 ?  195  ILE B O    1 
ATOM   8645  C CB   . ILE B 1 229 ? 14.423  35.354  42.888 1.00 9.83  ?  195  ILE B CB   1 
ATOM   8646  C CG1  . ILE B 1 229 ? 14.742  34.964  41.456 1.00 11.96 ?  195  ILE B CG1  1 
ATOM   8647  C CG2  . ILE B 1 229 ? 12.937  35.654  43.047 1.00 10.95 ?  195  ILE B CG2  1 
ATOM   8648  C CD1  . ILE B 1 229 ? 14.181  33.606  41.045 1.00 13.38 ?  195  ILE B CD1  1 
ATOM   8649  H H    . ILE B 1 229 ? 16.809  35.331  43.324 1.00 15.32 ?  195  ILE B H    1 
ATOM   8650  H HA   . ILE B 1 229 ? 15.193  37.248  42.622 1.00 13.28 ?  195  ILE B HA   1 
ATOM   8651  H HB   . ILE B 1 229 ? 14.649  34.607  43.466 1.00 11.79 ?  195  ILE B HB   1 
ATOM   8652  H HG12 . ILE B 1 229 ? 14.366  35.631  40.861 1.00 14.35 ?  195  ILE B HG12 1 
ATOM   8653  H HG13 . ILE B 1 229 ? 15.706  34.930  41.350 1.00 14.35 ?  195  ILE B HG13 1 
ATOM   8654  H HG21 . ILE B 1 229 ? 12.425  34.940  42.637 1.00 13.14 ?  195  ILE B HG21 1 
ATOM   8655  H HG22 . ILE B 1 229 ? 12.726  35.712  43.992 1.00 13.14 ?  195  ILE B HG22 1 
ATOM   8656  H HG23 . ILE B 1 229 ? 12.737  36.497  42.611 1.00 13.14 ?  195  ILE B HG23 1 
ATOM   8657  H HD11 . ILE B 1 229 ? 14.458  33.413  40.135 1.00 16.06 ?  195  ILE B HD11 1 
ATOM   8658  H HD12 . ILE B 1 229 ? 14.525  32.927  41.646 1.00 16.06 ?  195  ILE B HD12 1 
ATOM   8659  H HD13 . ILE B 1 229 ? 13.213  33.635  41.097 1.00 16.06 ?  195  ILE B HD13 1 
ATOM   8660  N N    . GLU B 1 230 ? 15.068  36.528  45.738 1.00 10.99 ?  196  GLU B N    1 
ATOM   8661  C CA   . GLU B 1 230 ? 14.647  37.020  47.041 1.00 11.27 ?  196  GLU B CA   1 
ATOM   8662  C C    . GLU B 1 230 ? 15.252  38.387  47.359 1.00 13.71 ?  196  GLU B C    1 
ATOM   8663  O O    . GLU B 1 230 ? 14.557  39.285  47.859 1.00 12.63 ?  196  GLU B O    1 
ATOM   8664  C CB   . GLU B 1 230 ? 15.021  35.990  48.111 1.00 13.36 ?  196  GLU B CB   1 
ATOM   8665  C CG   . GLU B 1 230 ? 14.670  36.390  49.526 1.00 13.92 ?  196  GLU B CG   1 
ATOM   8666  C CD   . GLU B 1 230 ? 14.950  35.275  50.508 1.00 21.00 ?  196  GLU B CD   1 
ATOM   8667  O OE1  . GLU B 1 230 ? 14.665  34.098  50.184 1.00 17.99 ?  196  GLU B OE1  1 
ATOM   8668  O OE2  . GLU B 1 230 ? 15.509  35.563  51.583 1.00 24.86 ?  196  GLU B OE2  1 
ATOM   8669  H H    . GLU B 1 230 ? 15.520  35.797  45.770 1.00 13.19 ?  196  GLU B H    1 
ATOM   8670  H HA   . GLU B 1 230 ? 13.684  37.132  47.038 1.00 13.53 ?  196  GLU B HA   1 
ATOM   8671  H HB2  . GLU B 1 230 ? 14.555  35.162  47.918 1.00 16.04 ?  196  GLU B HB2  1 
ATOM   8672  H HB3  . GLU B 1 230 ? 15.980  35.847  48.078 1.00 16.04 ?  196  GLU B HB3  1 
ATOM   8673  H HG2  . GLU B 1 230 ? 15.200  37.161  49.782 1.00 16.71 ?  196  GLU B HG2  1 
ATOM   8674  H HG3  . GLU B 1 230 ? 13.726  36.606  49.572 1.00 16.71 ?  196  GLU B HG3  1 
ATOM   8675  N N    . ASN B 1 231 ? 16.556  38.551  47.115 1.00 12.61 ?  197  ASN B N    1 
ATOM   8676  C CA   . ASN B 1 231 ? 17.191  39.842  47.373 1.00 14.45 ?  197  ASN B CA   1 
ATOM   8677  C C    . ASN B 1 231 ? 16.526  40.941  46.558 1.00 12.28 ?  197  ASN B C    1 
ATOM   8678  O O    . ASN B 1 231 ? 16.250  42.038  47.070 1.00 12.68 ?  197  ASN B O    1 
ATOM   8679  C CB   . ASN B 1 231 ? 18.680  39.745  47.031 1.00 17.38 ?  197  ASN B CB   1 
ATOM   8680  C CG   . ASN B 1 231 ? 19.407  41.069  47.177 1.00 22.84 ?  197  ASN B CG   1 
ATOM   8681  O OD1  . ASN B 1 231 ? 19.651  41.526  48.288 1.00 29.22 ?  197  ASN B OD1  1 
ATOM   8682  N ND2  . ASN B 1 231 ? 19.769  41.681  46.050 1.00 24.33 ?  197  ASN B ND2  1 
ATOM   8683  H H    . ASN B 1 231 ? 17.082  37.945  46.806 1.00 15.13 ?  197  ASN B H    1 
ATOM   8684  H HA   . ASN B 1 231 ? 17.103  40.069  48.312 1.00 17.34 ?  197  ASN B HA   1 
ATOM   8685  H HB2  . ASN B 1 231 ? 19.099  39.106  47.627 1.00 20.85 ?  197  ASN B HB2  1 
ATOM   8686  H HB3  . ASN B 1 231 ? 18.774  39.452  46.111 1.00 20.85 ?  197  ASN B HB3  1 
ATOM   8687  H HD21 . ASN B 1 231 ? 19.588  41.324  45.289 1.00 29.20 ?  197  ASN B HD21 1 
ATOM   8688  H HD22 . ASN B 1 231 ? 20.184  42.434  46.083 1.00 29.20 ?  197  ASN B HD22 1 
ATOM   8689  N N    . SER B 1 232 ? 16.267  40.673  45.281 1.00 11.12 ?  198  SER B N    1 
ATOM   8690  C CA   . SER B 1 232 ? 15.639  41.669  44.422 1.00 11.42 ?  198  SER B CA   1 
ATOM   8691  C C    . SER B 1 232 ? 14.213  41.966  44.875 1.00 11.21 ?  198  SER B C    1 
ATOM   8692  O O    . SER B 1 232 ? 13.778  43.126  44.862 1.00 12.33 ?  198  SER B O    1 
ATOM   8693  C CB   . SER B 1 232 ? 15.647  41.194  42.972 1.00 11.50 ?  198  SER B CB   1 
ATOM   8694  O OG   . SER B 1 232 ? 16.979  40.984  42.528 1.00 14.04 ?  198  SER B OG   1 
ATOM   8695  H H    . SER B 1 232 ? 16.443  39.928  44.891 1.00 13.34 ?  198  SER B H    1 
ATOM   8696  H HA   . SER B 1 232 ? 16.152  42.491  44.471 1.00 13.70 ?  198  SER B HA   1 
ATOM   8697  H HB2  . SER B 1 232 ? 15.156  40.360  42.909 1.00 13.80 ?  198  SER B HB2  1 
ATOM   8698  H HB3  . SER B 1 232 ? 15.229  41.868  42.414 1.00 13.80 ?  198  SER B HB3  1 
ATOM   8699  H HG   . SER B 1 232 ? 17.403  41.709  42.536 1.00 16.85 ?  198  SER B HG   1 
ATOM   8700  N N    . TYR B 1 233 ? 13.483  40.931  45.293 1.00 10.33 ?  199  TYR B N    1 
ATOM   8701  C CA   . TYR B 1 233 ? 12.124  41.096  45.813 1.00 10.62 ?  199  TYR B CA   1 
ATOM   8702  C C    . TYR B 1 233 ? 12.094  42.085  46.979 1.00 11.21 ?  199  TYR B C    1 
ATOM   8703  O O    . TYR B 1 233 ? 11.260  43.000  47.011 1.00 11.02 ?  199  TYR B O    1 
ATOM   8704  C CB   . TYR B 1 233 ? 11.561  39.728  46.237 1.00 9.77  ?  199  TYR B CB   1 
ATOM   8705  C CG   . TYR B 1 233 ? 10.321  39.840  47.099 1.00 9.01  ?  199  TYR B CG   1 
ATOM   8706  C CD1  . TYR B 1 233 ? 9.054   40.018  46.531 1.00 9.97  ?  199  TYR B CD1  1 
ATOM   8707  C CD2  . TYR B 1 233 ? 10.399  39.800  48.475 1.00 10.77 ?  199  TYR B CD2  1 
ATOM   8708  C CE1  . TYR B 1 233 ? 7.925   40.141  47.327 1.00 9.39  ?  199  TYR B CE1  1 
ATOM   8709  C CE2  . TYR B 1 233 ? 9.278   39.941  49.274 1.00 9.19  ?  199  TYR B CE2  1 
ATOM   8710  C CZ   . TYR B 1 233 ? 8.034   40.107  48.697 1.00 9.28  ?  199  TYR B CZ   1 
ATOM   8711  O OH   . TYR B 1 233 ? 6.940   40.253  49.512 1.00 9.73  ?  199  TYR B OH   1 
ATOM   8712  H H    . TYR B 1 233 ? 13.753  40.115  45.287 1.00 12.40 ?  199  TYR B H    1 
ATOM   8713  H HA   . TYR B 1 233 ? 11.557  41.451  45.110 1.00 12.74 ?  199  TYR B HA   1 
ATOM   8714  H HB2  . TYR B 1 233 ? 11.329  39.222  45.442 1.00 11.72 ?  199  TYR B HB2  1 
ATOM   8715  H HB3  . TYR B 1 233 ? 12.237  39.253  46.746 1.00 11.72 ?  199  TYR B HB3  1 
ATOM   8716  H HD1  . TYR B 1 233 ? 8.968   40.054  45.606 1.00 11.97 ?  199  TYR B HD1  1 
ATOM   8717  H HD2  . TYR B 1 233 ? 11.229  39.676  48.878 1.00 12.92 ?  199  TYR B HD2  1 
ATOM   8718  H HE1  . TYR B 1 233 ? 7.090   40.248  46.931 1.00 11.26 ?  199  TYR B HE1  1 
ATOM   8719  H HE2  . TYR B 1 233 ? 9.362   39.925  50.200 1.00 11.02 ?  199  TYR B HE2  1 
ATOM   8720  H HH   . TYR B 1 233 ? 6.949   41.012  49.871 1.00 11.68 ?  199  TYR B HH   1 
ATOM   8721  N N    . PHE B 1 234 ? 13.006  41.937  47.945 1.00 10.43 ?  200  PHE B N    1 
ATOM   8722  C CA   . PHE B 1 234 ? 13.014  42.860  49.077 1.00 9.96  ?  200  PHE B CA   1 
ATOM   8723  C C    . PHE B 1 234 ? 13.304  44.294  48.623 1.00 12.49 ?  200  PHE B C    1 
ATOM   8724  O O    . PHE B 1 234 ? 12.701  45.248  49.134 1.00 12.69 ?  200  PHE B O    1 
ATOM   8725  C CB   . PHE B 1 234 ? 14.025  42.417  50.136 1.00 12.36 ?  200  PHE B CB   1 
ATOM   8726  C CG   . PHE B 1 234 ? 13.592  41.211  50.919 1.00 12.75 ?  200  PHE B CG   1 
ATOM   8727  C CD1  . PHE B 1 234 ? 12.335  41.156  51.505 1.00 16.33 ?  200  PHE B CD1  1 
ATOM   8728  C CD2  . PHE B 1 234 ? 14.451  40.141  51.093 1.00 18.69 ?  200  PHE B CD2  1 
ATOM   8729  C CE1  . PHE B 1 234 ? 11.948  40.039  52.242 1.00 21.10 ?  200  PHE B CE1  1 
ATOM   8730  C CE2  . PHE B 1 234 ? 14.061  39.029  51.833 1.00 19.79 ?  200  PHE B CE2  1 
ATOM   8731  C CZ   . PHE B 1 234 ? 12.817  38.992  52.398 1.00 18.03 ?  200  PHE B CZ   1 
ATOM   8732  H H    . PHE B 1 234 ? 13.612  41.327  47.966 1.00 12.52 ?  200  PHE B H    1 
ATOM   8733  H HA   . PHE B 1 234 ? 12.136  42.842  49.489 1.00 11.95 ?  200  PHE B HA   1 
ATOM   8734  H HB2  . PHE B 1 234 ? 14.862  42.200  49.696 1.00 14.83 ?  200  PHE B HB2  1 
ATOM   8735  H HB3  . PHE B 1 234 ? 14.159  43.145  50.763 1.00 14.83 ?  200  PHE B HB3  1 
ATOM   8736  H HD1  . PHE B 1 234 ? 11.747  41.870  51.405 1.00 19.60 ?  200  PHE B HD1  1 
ATOM   8737  H HD2  . PHE B 1 234 ? 15.298  40.165  50.711 1.00 22.43 ?  200  PHE B HD2  1 
ATOM   8738  H HE1  . PHE B 1 234 ? 11.102  40.004  52.627 1.00 25.32 ?  200  PHE B HE1  1 
ATOM   8739  H HE2  . PHE B 1 234 ? 14.644  38.313  51.943 1.00 23.75 ?  200  PHE B HE2  1 
ATOM   8740  H HZ   . PHE B 1 234 ? 12.559  38.248  52.893 1.00 21.63 ?  200  PHE B HZ   1 
ATOM   8741  N N    . SER B 1 235 ? 14.210  44.466  47.659 1.00 12.17 ?  201  SER B N    1 
ATOM   8742  C CA   . SER B 1 235 ? 14.488  45.797  47.131 1.00 12.56 ?  201  SER B CA   1 
ATOM   8743  C C    . SER B 1 235 ? 13.238  46.395  46.495 1.00 11.64 ?  201  SER B C    1 
ATOM   8744  O O    . SER B 1 235 ? 12.926  47.584  46.687 1.00 13.05 ?  201  SER B O    1 
ATOM   8745  C CB   . SER B 1 235 ? 15.612  45.676  46.099 1.00 15.26 ?  201  SER B CB   1 
ATOM   8746  O OG   . SER B 1 235 ? 15.932  46.935  45.541 1.00 26.96 ?  201  SER B OG   1 
ATOM   8747  H H    . SER B 1 235 ? 14.671  43.836  47.299 1.00 14.60 ?  201  SER B H    1 
ATOM   8748  H HA   . SER B 1 235 ? 14.772  46.392  47.842 1.00 15.08 ?  201  SER B HA   1 
ATOM   8749  H HB2  . SER B 1 235 ? 16.401  45.315  46.535 1.00 18.31 ?  201  SER B HB2  1 
ATOM   8750  H HB3  . SER B 1 235 ? 15.324  45.081  45.389 1.00 18.31 ?  201  SER B HB3  1 
ATOM   8751  H HG   . SER B 1 235 ? 16.531  46.847  44.958 1.00 32.35 ?  201  SER B HG   1 
ATOM   8752  N N    . MET B 1 236 ? 12.496  45.583  45.745 1.00 11.21 ?  202  MET B N    1 
ATOM   8753  C CA   . MET B 1 236 ? 11.269  46.050  45.124 1.00 10.82 ?  202  MET B CA   1 
ATOM   8754  C C    . MET B 1 236 ? 10.203  46.420  46.149 1.00 10.79 ?  202  MET B C    1 
ATOM   8755  O O    . MET B 1 236 ? 9.511   47.441  45.994 1.00 10.98 ?  202  MET B O    1 
ATOM   8756  C CB   . MET B 1 236 ? 10.719  45.023  44.135 1.00 10.75 ?  202  MET B CB   1 
ATOM   8757  C CG   . MET B 1 236 ? 11.537  44.849  42.876 1.00 10.01 ?  202  MET B CG   1 
ATOM   8758  S SD   . MET B 1 236 ? 11.302  43.264  42.050 1.00 11.55 ?  202  MET B SD   1 
ATOM   8759  C CE   . MET B 1 236 ? 9.748   43.580  41.269 1.00 12.85 ?  202  MET B CE   1 
ATOM   8760  H H    . MET B 1 236 ? 12.682  44.759  45.583 1.00 13.45 ?  202  MET B H    1 
ATOM   8761  H HA   . MET B 1 236 ? 11.500  46.844  44.618 1.00 12.98 ?  202  MET B HA   1 
ATOM   8762  H HB2  . MET B 1 236 ? 10.680  44.160  44.578 1.00 12.90 ?  202  MET B HB2  1 
ATOM   8763  H HB3  . MET B 1 236 ? 9.829   45.299  43.868 1.00 12.90 ?  202  MET B HB3  1 
ATOM   8764  H HG2  . MET B 1 236 ? 11.291  45.546  42.248 1.00 12.01 ?  202  MET B HG2  1 
ATOM   8765  H HG3  . MET B 1 236 ? 12.477  44.924  43.104 1.00 12.01 ?  202  MET B HG3  1 
ATOM   8766  H HE1  . MET B 1 236 ? 9.485   42.798  40.760 1.00 15.42 ?  202  MET B HE1  1 
ATOM   8767  H HE2  . MET B 1 236 ? 9.084   43.769  41.951 1.00 15.42 ?  202  MET B HE2  1 
ATOM   8768  H HE3  . MET B 1 236 ? 9.841   44.344  40.678 1.00 15.42 ?  202  MET B HE3  1 
ATOM   8769  N N    . MET B 1 237 ? 10.047  45.615  47.201 1.00 9.82  ?  203  MET B N    1 
ATOM   8770  C CA   . MET B 1 237 ? 9.061   45.960  48.217 1.00 9.90  ?  203  MET B CA   1 
ATOM   8771  C C    . MET B 1 237 ? 9.437   47.219  48.975 1.00 12.37 ?  203  MET B C    1 
ATOM   8772  O O    . MET B 1 237 ? 8.556   48.018  49.309 1.00 11.19 ?  203  MET B O    1 
ATOM   8773  C CB   . MET B 1 237 ? 8.662   44.807  49.145 1.00 10.41 ?  203  MET B CB   1 
ATOM   8774  C CG   . MET B 1 237 ? 8.326   43.533  48.388 1.00 9.81  ?  203  MET B CG   1 
ATOM   8775  S SD   . MET B 1 237 ? 6.730   43.694  47.551 1.00 10.56 ?  203  MET B SD   1 
ATOM   8776  C CE   . MET B 1 237 ? 7.277   43.962  45.863 1.00 12.75 ?  203  MET B CE   1 
ATOM   8777  H H    . MET B 1 237 ? 10.485  44.889  47.344 1.00 11.79 ?  203  MET B H    1 
ATOM   8778  H HA   . MET B 1 237 ? 8.241   46.129  47.727 1.00 11.88 ?  203  MET B HA   1 
ATOM   8779  H HB2  . MET B 1 237 ? 9.400   44.614  49.745 1.00 12.50 ?  203  MET B HB2  1 
ATOM   8780  H HB3  . MET B 1 237 ? 7.879   45.069  49.655 1.00 12.50 ?  203  MET B HB3  1 
ATOM   8781  H HG2  . MET B 1 237 ? 9.009   43.362  47.720 1.00 11.78 ?  203  MET B HG2  1 
ATOM   8782  H HG3  . MET B 1 237 ? 8.275   42.790  49.009 1.00 11.78 ?  203  MET B HG3  1 
ATOM   8783  H HE1  . MET B 1 237 ? 6.500   44.016  45.285 1.00 15.30 ?  203  MET B HE1  1 
ATOM   8784  H HE2  . MET B 1 237 ? 7.778   44.791  45.822 1.00 15.30 ?  203  MET B HE2  1 
ATOM   8785  H HE3  . MET B 1 237 ? 7.840   43.221  45.593 1.00 15.30 ?  203  MET B HE3  1 
ATOM   8786  N N    . SER B 1 238 ? 10.730  47.416  49.244 1.00 11.47 ?  204  SER B N    1 
ATOM   8787  C CA   . SER B 1 238 ? 11.174  48.664  49.866 1.00 13.22 ?  204  SER B CA   1 
ATOM   8788  C C    . SER B 1 238 ? 10.868  49.854  48.971 1.00 12.23 ?  204  SER B C    1 
ATOM   8789  O O    . SER B 1 238 ? 10.409  50.899  49.451 1.00 12.66 ?  204  SER B O    1 
ATOM   8790  C CB   . SER B 1 238 ? 12.665  48.603  50.153 1.00 14.40 ?  204  SER B CB   1 
ATOM   8791  O OG   . SER B 1 238 ? 12.917  47.731  51.230 1.00 20.94 ?  204  SER B OG   1 
ATOM   8792  H H    . SER B 1 238 ? 11.359  46.853  49.078 1.00 13.76 ?  204  SER B H    1 
ATOM   8793  H HA   . SER B 1 238 ? 10.705  48.777  50.708 1.00 15.86 ?  204  SER B HA   1 
ATOM   8794  H HB2  . SER B 1 238 ? 13.128  48.278  49.365 1.00 17.28 ?  204  SER B HB2  1 
ATOM   8795  H HB3  . SER B 1 238 ? 12.982  49.491  50.381 1.00 17.28 ?  204  SER B HB3  1 
ATOM   8796  H HG   . SER B 1 238 ? 13.737  47.727  51.412 1.00 25.13 ?  204  SER B HG   1 
ATOM   8797  N N    . ARG B 1 239 ? 11.055  49.704  47.661 1.00 11.68 ?  205  ARG B N    1 
ATOM   8798  C CA   . ARG B 1 239 ? 10.734  50.788  46.737 1.00 13.22 ?  205  ARG B CA   1 
ATOM   8799  C C    . ARG B 1 239 ? 9.251   51.132  46.789 1.00 13.35 ?  205  ARG B C    1 
ATOM   8800  O O    . ARG B 1 239 ? 8.874   52.311  46.861 1.00 14.39 ?  205  ARG B O    1 
ATOM   8801  C CB   . ARG B 1 239 ? 11.119  50.416  45.305 1.00 15.27 ?  205  ARG B CB   1 
ATOM   8802  C CG   . ARG B 1 239 ? 12.609  50.468  44.987 1.00 16.19 ?  205  ARG B CG   1 
ATOM   8803  C CD   . ARG B 1 239 ? 13.054  51.865  44.540 1.00 19.43 ?  205  ARG B CD   1 
ATOM   8804  N NE   . ARG B 1 239 ? 12.545  52.262  43.228 1.00 19.29 ?  205  ARG B NE   1 
ATOM   8805  C CZ   . ARG B 1 239 ? 13.045  51.888  42.057 1.00 16.29 ?  205  ARG B CZ   1 
ATOM   8806  N NH1  . ARG B 1 239 ? 14.102  51.098  41.974 1.00 18.34 ?  205  ARG B NH1  1 
ATOM   8807  N NH2  . ARG B 1 239 ? 12.474  52.327  40.938 1.00 16.34 ?  205  ARG B NH2  1 
ATOM   8808  H H    . ARG B 1 239 ? 11.362  48.993  47.286 1.00 14.02 ?  205  ARG B H    1 
ATOM   8809  H HA   . ARG B 1 239 ? 11.252  51.564  47.001 1.00 15.86 ?  205  ARG B HA   1 
ATOM   8810  H HB2  . ARG B 1 239 ? 10.820  49.509  45.136 1.00 18.32 ?  205  ARG B HB2  1 
ATOM   8811  H HB3  . ARG B 1 239 ? 10.673  51.030  44.701 1.00 18.32 ?  205  ARG B HB3  1 
ATOM   8812  H HG2  . ARG B 1 239 ? 13.113  50.230  45.780 1.00 19.42 ?  205  ARG B HG2  1 
ATOM   8813  H HG3  . ARG B 1 239 ? 12.804  49.845  44.270 1.00 19.42 ?  205  ARG B HG3  1 
ATOM   8814  H HD2  . ARG B 1 239 ? 12.738  52.514  45.187 1.00 23.31 ?  205  ARG B HD2  1 
ATOM   8815  H HD3  . ARG B 1 239 ? 14.023  51.884  44.497 1.00 23.31 ?  205  ARG B HD3  1 
ATOM   8816  H HE   . ARG B 1 239 ? 11.862  52.784  43.214 1.00 23.15 ?  205  ARG B HE   1 
ATOM   8817  H HH11 . ARG B 1 239 ? 14.484  50.813  42.690 1.00 22.01 ?  205  ARG B HH11 1 
ATOM   8818  H HH12 . ARG B 1 239 ? 14.408  50.868  41.203 1.00 22.01 ?  205  ARG B HH12 1 
ATOM   8819  H HH21 . ARG B 1 239 ? 11.790  52.847  40.979 1.00 19.61 ?  205  ARG B HH21 1 
ATOM   8820  H HH22 . ARG B 1 239 ? 12.789  52.091  40.173 1.00 19.61 ?  205  ARG B HH22 1 
ATOM   8821  N N    . LEU B 1 240 ? 8.382   50.117  46.720 1.00 11.95 ?  206  LEU B N    1 
ATOM   8822  C CA   . LEU B 1 240 ? 6.951   50.393  46.718 1.00 10.62 ?  206  LEU B CA   1 
ATOM   8823  C C    . LEU B 1 240 ? 6.491   50.979  48.042 1.00 11.31 ?  206  LEU B C    1 
ATOM   8824  O O    . LEU B 1 240 ? 5.599   51.836  48.069 1.00 11.13 ?  206  LEU B O    1 
ATOM   8825  C CB   . LEU B 1 240 ? 6.154   49.115  46.489 1.00 15.14 ?  206  LEU B CB   1 
ATOM   8826  C CG   . LEU B 1 240 ? 6.020   48.558  45.094 1.00 15.76 ?  206  LEU B CG   1 
ATOM   8827  C CD1  . LEU B 1 240 ? 5.055   47.381  45.184 1.00 15.85 ?  206  LEU B CD1  1 
ATOM   8828  C CD2  . LEU B 1 240 ? 5.517   49.595  44.144 1.00 14.67 ?  206  LEU B CD2  1 
ATOM   8829  H H    A LEU B 1 240 ? 8.594   49.285  46.675 0.26 14.34 ?  206  LEU B H    1 
ATOM   8830  H H    B LEU B 1 240 ? 8.594   49.285  46.675 0.74 14.34 ?  206  LEU B H    1 
ATOM   8831  H HA   . LEU B 1 240 ? 6.786   51.021  45.997 1.00 12.74 ?  206  LEU B HA   1 
ATOM   8832  H HB2  . LEU B 1 240 ? 6.570   48.418  47.020 1.00 18.17 ?  206  LEU B HB2  1 
ATOM   8833  H HB3  . LEU B 1 240 ? 5.252   49.278  46.804 1.00 18.17 ?  206  LEU B HB3  1 
ATOM   8834  H HG   . LEU B 1 240 ? 6.878   48.270  44.745 1.00 18.91 ?  206  LEU B HG   1 
ATOM   8835  H HD11 . LEU B 1 240 ? 4.978   46.968  44.310 1.00 19.02 ?  206  LEU B HD11 1 
ATOM   8836  H HD12 . LEU B 1 240 ? 5.400   46.738  45.824 1.00 19.02 ?  206  LEU B HD12 1 
ATOM   8837  H HD13 . LEU B 1 240 ? 4.188   47.704  45.475 1.00 19.02 ?  206  LEU B HD13 1 
ATOM   8838  H HD21 . LEU B 1 240 ? 5.356   49.182  43.281 1.00 17.61 ?  206  LEU B HD21 1 
ATOM   8839  H HD22 . LEU B 1 240 ? 4.691   49.968  44.491 1.00 17.61 ?  206  LEU B HD22 1 
ATOM   8840  H HD23 . LEU B 1 240 ? 6.184   50.294  44.056 1.00 17.61 ?  206  LEU B HD23 1 
ATOM   8841  N N    . LYS B 1 241 ? 7.060   50.508  49.160 1.00 12.23 ?  207  LYS B N    1 
ATOM   8842  C CA   . LYS B 1 241 ? 6.676   51.051  50.453 1.00 11.81 ?  207  LYS B CA   1 
ATOM   8843  C C    . LYS B 1 241 ? 6.826   52.560  50.453 1.00 12.00 ?  207  LYS B C    1 
ATOM   8844  O O    . LYS B 1 241 ? 6.008   53.280  51.042 1.00 13.42 ?  207  LYS B O    1 
ATOM   8845  C CB   . LYS B 1 241 ? 7.525   50.437  51.560 1.00 12.18 ?  207  LYS B CB   1 
ATOM   8846  C CG   . LYS B 1 241 ? 7.135   50.894  52.946 1.00 12.61 ?  207  LYS B CG   1 
ATOM   8847  C CD   . LYS B 1 241 ? 7.953   50.227  53.999 1.00 13.65 ?  207  LYS B CD   1 
ATOM   8848  C CE   . LYS B 1 241 ? 7.489   50.659  55.383 1.00 15.93 ?  207  LYS B CE   1 
ATOM   8849  N NZ   . LYS B 1 241 ? 8.238   49.982  56.459 1.00 20.33 ?  207  LYS B NZ   1 
ATOM   8850  H H    . LYS B 1 241 ? 7.656   49.889  49.190 1.00 14.68 ?  207  LYS B H    1 
ATOM   8851  H HA   . LYS B 1 241 ? 5.750   50.824  50.633 1.00 14.17 ?  207  LYS B HA   1 
ATOM   8852  H HB2  . LYS B 1 241 ? 7.430   49.472  51.527 1.00 14.62 ?  207  LYS B HB2  1 
ATOM   8853  H HB3  . LYS B 1 241 ? 8.452   50.684  51.415 1.00 14.62 ?  207  LYS B HB3  1 
ATOM   8854  H HG2  . LYS B 1 241 ? 7.271   51.852  53.018 1.00 15.13 ?  207  LYS B HG2  1 
ATOM   8855  H HG3  . LYS B 1 241 ? 6.203   50.679  53.104 1.00 15.13 ?  207  LYS B HG3  1 
ATOM   8856  H HD2  . LYS B 1 241 ? 7.855   49.265  53.927 1.00 16.38 ?  207  LYS B HD2  1 
ATOM   8857  H HD3  . LYS B 1 241 ? 8.885   50.474  53.894 1.00 16.38 ?  207  LYS B HD3  1 
ATOM   8858  H HE2  . LYS B 1 241 ? 7.621   51.615  55.479 1.00 19.12 ?  207  LYS B HE2  1 
ATOM   8859  H HE3  . LYS B 1 241 ? 6.550   50.442  55.486 1.00 19.12 ?  207  LYS B HE3  1 
ATOM   8860  H HZ1  . LYS B 1 241 ? 8.103   49.104  56.418 1.00 24.40 ?  207  LYS B HZ1  1 
ATOM   8861  H HZ2  . LYS B 1 241 ? 9.109   50.145  56.373 1.00 24.40 ?  207  LYS B HZ2  1 
ATOM   8862  H HZ3  . LYS B 1 241 ? 7.966   50.280  57.253 1.00 24.40 ?  207  LYS B HZ3  1 
ATOM   8863  N N    . GLU B 1 242 ? 7.861   53.055  49.797 1.00 12.05 ?  208  GLU B N    1 
ATOM   8864  C CA   . GLU B 1 242 ? 8.068   54.498  49.771 1.00 12.39 ?  208  GLU B CA   1 
ATOM   8865  C C    . GLU B 1 242 ? 7.225   55.169  48.701 1.00 13.05 ?  208  GLU B C    1 
ATOM   8866  O O    . GLU B 1 242 ? 6.591   56.201  48.964 1.00 14.70 ?  208  GLU B O    1 
ATOM   8867  C CB   . GLU B 1 242 ? 9.553   54.792  49.567 1.00 16.05 ?  208  GLU B CB   1 
ATOM   8868  C CG   . GLU B 1 242 ? 10.377  54.229  50.711 1.00 25.64 ?  208  GLU B CG   1 
ATOM   8869  C CD   . GLU B 1 242 ? 9.955   54.783  52.062 1.00 37.84 ?  208  GLU B CD   1 
ATOM   8870  O OE1  . GLU B 1 242 ? 9.910   53.989  53.044 1.00 27.01 ?  208  GLU B OE1  1 
ATOM   8871  O OE2  . GLU B 1 242 ? 9.703   56.012  52.140 1.00 35.47 ?  208  GLU B OE2  1 
ATOM   8872  H H    . GLU B 1 242 ? 8.445   52.592  49.369 1.00 14.46 ?  208  GLU B H    1 
ATOM   8873  H HA   . GLU B 1 242 ? 7.798   54.874  50.623 1.00 14.86 ?  208  GLU B HA   1 
ATOM   8874  H HB2  . GLU B 1 242 ? 9.853   54.382  48.740 1.00 19.26 ?  208  GLU B HB2  1 
ATOM   8875  H HB3  . GLU B 1 242 ? 9.691   55.751  49.531 1.00 19.26 ?  208  GLU B HB3  1 
ATOM   8876  H HG2  . GLU B 1 242 ? 10.270  53.266  50.734 1.00 30.77 ?  208  GLU B HG2  1 
ATOM   8877  H HG3  . GLU B 1 242 ? 11.309  54.456  50.571 1.00 30.77 ?  208  GLU B HG3  1 
ATOM   8878  N N    . SER B 1 243 ? 7.210   54.626  47.485 1.00 11.42 ?  209  SER B N    1 
ATOM   8879  C CA   . SER B 1 243 ? 6.500   55.325  46.421 1.00 12.28 ?  209  SER B CA   1 
ATOM   8880  C C    . SER B 1 243 ? 4.988   55.310  46.634 1.00 11.67 ?  209  SER B C    1 
ATOM   8881  O O    . SER B 1 243 ? 4.289   56.228  46.181 1.00 13.68 ?  209  SER B O    1 
ATOM   8882  C CB   . SER B 1 243 ? 6.852   54.758  45.054 1.00 14.46 ?  209  SER B CB   1 
ATOM   8883  O OG   . SER B 1 243 ? 6.401   53.418  44.948 1.00 14.10 ?  209  SER B OG   1 
ATOM   8884  H H    . SER B 1 243 ? 7.586   53.885  47.261 1.00 13.71 ?  209  SER B H    1 
ATOM   8885  H HA   . SER B 1 243 ? 6.796   56.249  46.430 1.00 14.73 ?  209  SER B HA   1 
ATOM   8886  H HB2  . SER B 1 243 ? 6.423   55.293  44.368 1.00 17.35 ?  209  SER B HB2  1 
ATOM   8887  H HB3  . SER B 1 243 ? 7.814   54.780  44.938 1.00 17.35 ?  209  SER B HB3  1 
ATOM   8888  H HG   . SER B 1 243 ? 6.623   53.099  44.203 1.00 16.92 ?  209  SER B HG   1 
ATOM   8889  N N    . LEU B 1 244 ? 4.453   54.283  47.297 1.00 11.08 ?  210  LEU B N    1 
ATOM   8890  C CA   . LEU B 1 244 ? 3.022   54.182  47.541 1.00 10.34 ?  210  LEU B CA   1 
ATOM   8891  C C    . LEU B 1 244 ? 2.636   54.587  48.956 1.00 11.48 ?  210  LEU B C    1 
ATOM   8892  O O    . LEU B 1 244 ? 1.580   54.193  49.461 1.00 11.13 ?  210  LEU B O    1 
ATOM   8893  C CB   . LEU B 1 244 ? 2.527   52.774  47.215 1.00 10.10 ?  210  LEU B CB   1 
ATOM   8894  C CG   . LEU B 1 244 ? 2.801   52.329  45.785 1.00 12.54 ?  210  LEU B CG   1 
ATOM   8895  C CD1  . LEU B 1 244 ? 2.135   50.969  45.560 1.00 12.42 ?  210  LEU B CD1  1 
ATOM   8896  C CD2  . LEU B 1 244 ? 2.324   53.346  44.778 1.00 14.08 ?  210  LEU B CD2  1 
ATOM   8897  H H    . LEU B 1 244 ? 4.908   53.627  47.616 1.00 13.29 ?  210  LEU B H    1 
ATOM   8898  H HA   . LEU B 1 244 ? 2.567   54.797  46.944 1.00 12.41 ?  210  LEU B HA   1 
ATOM   8899  H HB2  . LEU B 1 244 ? 2.968   52.147  47.809 1.00 12.12 ?  210  LEU B HB2  1 
ATOM   8900  H HB3  . LEU B 1 244 ? 1.567   52.744  47.354 1.00 12.12 ?  210  LEU B HB3  1 
ATOM   8901  H HG   . LEU B 1 244 ? 3.758   52.246  45.647 1.00 15.05 ?  210  LEU B HG   1 
ATOM   8902  H HD11 . LEU B 1 244 ? 2.363   50.649  44.674 1.00 14.91 ?  210  LEU B HD11 1 
ATOM   8903  H HD12 . LEU B 1 244 ? 2.456   50.346  46.230 1.00 14.91 ?  210  LEU B HD12 1 
ATOM   8904  H HD13 . LEU B 1 244 ? 1.174   51.072  45.638 1.00 14.91 ?  210  LEU B HD13 1 
ATOM   8905  H HD21 . LEU B 1 244 ? 2.331   52.944  43.896 1.00 16.90 ?  210  LEU B HD21 1 
ATOM   8906  H HD22 . LEU B 1 244 ? 1.423   53.621  45.010 1.00 16.90 ?  210  LEU B HD22 1 
ATOM   8907  H HD23 . LEU B 1 244 ? 2.919   54.112  44.797 1.00 16.90 ?  210  LEU B HD23 1 
ATOM   8908  N N    . SER B 1 245 ? 3.450   55.435  49.598 1.00 12.70 ?  211  SER B N    1 
ATOM   8909  C CA   . SER B 1 245 ? 3.186   55.821  50.979 1.00 13.06 ?  211  SER B CA   1 
ATOM   8910  C C    . SER B 1 245 ? 1.925   56.662  51.145 1.00 12.39 ?  211  SER B C    1 
ATOM   8911  O O    . SER B 1 245 ? 1.438   56.793  52.276 1.00 15.42 ?  211  SER B O    1 
ATOM   8912  C CB   . SER B 1 245 ? 4.388   56.567  51.562 1.00 15.73 ?  211  SER B CB   1 
ATOM   8913  O OG   . SER B 1 245 ? 4.594   57.800  50.887 1.00 18.27 ?  211  SER B OG   1 
ATOM   8914  H H    . SER B 1 245 ? 4.152   55.794  49.256 1.00 15.24 ?  211  SER B H    1 
ATOM   8915  H HA   . SER B 1 245 ? 3.056   55.007  51.490 1.00 15.67 ?  211  SER B HA   1 
ATOM   8916  H HB2  . SER B 1 245 ? 4.224   56.745  52.502 1.00 18.87 ?  211  SER B HB2  1 
ATOM   8917  H HB3  . SER B 1 245 ? 5.181   56.016  51.462 1.00 18.87 ?  211  SER B HB3  1 
ATOM   8918  H HG   . SER B 1 245 ? 5.401   58.027  50.943 1.00 21.93 ?  211  SER B HG   1 
ATOM   8919  N N    . ASN B 1 246 ? 1.381   57.220  50.067 1.00 10.63 ?  212  ASN B N    1 
ATOM   8920  C CA   . ASN B 1 246 ? 0.109   57.925  50.117 1.00 13.25 ?  212  ASN B CA   1 
ATOM   8921  C C    . ASN B 1 246 ? -1.032  57.086  49.565 1.00 12.30 ?  212  ASN B C    1 
ATOM   8922  O O    . ASN B 1 246 ? -2.082  57.625  49.210 1.00 13.84 ?  212  ASN B O    1 
ATOM   8923  C CB   . ASN B 1 246 ? 0.209   59.263  49.384 1.00 14.38 ?  212  ASN B CB   1 
ATOM   8924  C CG   . ASN B 1 246 ? 1.205   60.196  50.025 1.00 20.01 ?  212  ASN B CG   1 
ATOM   8925  O OD1  . ASN B 1 246 ? 1.169   60.410  51.233 1.00 19.23 ?  212  ASN B OD1  1 
ATOM   8926  N ND2  . ASN B 1 246 ? 2.119   60.731  49.226 1.00 26.11 ?  212  ASN B ND2  1 
ATOM   8927  H H    . ASN B 1 246 ? 1.737   57.201  49.284 1.00 12.76 ?  212  ASN B H    1 
ATOM   8928  H HA   . ASN B 1 246 ? -0.098  58.125  51.044 1.00 15.90 ?  212  ASN B HA   1 
ATOM   8929  H HB2  . ASN B 1 246 ? 0.491   59.103  48.469 1.00 17.25 ?  212  ASN B HB2  1 
ATOM   8930  H HB3  . ASN B 1 246 ? -0.659  59.696  49.393 1.00 17.25 ?  212  ASN B HB3  1 
ATOM   8931  H HD21 . ASN B 1 246 ? 2.708   61.270  49.547 1.00 31.33 ?  212  ASN B HD21 1 
ATOM   8932  H HD22 . ASN B 1 246 ? 2.123   60.539  48.388 1.00 31.33 ?  212  ASN B HD22 1 
ATOM   8933  N N    . ASN B 1 247 ? -0.819  55.773  49.478 1.00 10.42 ?  213  ASN B N    1 
ATOM   8934  C CA   . ASN B 1 247 ? -1.763  54.817  48.928 1.00 10.45 ?  213  ASN B CA   1 
ATOM   8935  C C    . ASN B 1 247 ? -1.754  53.592  49.829 1.00 10.05 ?  213  ASN B C    1 
ATOM   8936  O O    . ASN B 1 247 ? -1.151  53.599  50.901 1.00 11.12 ?  213  ASN B O    1 
ATOM   8937  C CB   . ASN B 1 247 ? -1.347  54.484  47.494 1.00 9.30  ?  213  ASN B CB   1 
ATOM   8938  C CG   . ASN B 1 247 ? -1.482  55.650  46.564 1.00 11.38 ?  213  ASN B CG   1 
ATOM   8939  O OD1  . ASN B 1 247 ? -0.489  56.272  46.193 1.00 12.65 ?  213  ASN B OD1  1 
ATOM   8940  N ND2  . ASN B 1 247 ? -2.703  55.913  46.128 1.00 11.28 ?  213  ASN B ND2  1 
ATOM   8941  H H    . ASN B 1 247 ? -0.093  55.397  49.747 1.00 12.50 ?  213  ASN B H    1 
ATOM   8942  H HA   . ASN B 1 247 ? -2.660  55.188  48.928 1.00 12.54 ?  213  ASN B HA   1 
ATOM   8943  H HB2  . ASN B 1 247 ? -0.417  54.205  47.492 1.00 11.16 ?  213  ASN B HB2  1 
ATOM   8944  H HB3  . ASN B 1 247 ? -1.908  53.767  47.160 1.00 11.16 ?  213  ASN B HB3  1 
ATOM   8945  H HD21 . ASN B 1 247 ? -2.836  56.573  45.592 1.00 13.54 ?  213  ASN B HD21 1 
ATOM   8946  H HD22 . ASN B 1 247 ? -3.365  55.425  46.381 1.00 13.54 ?  213  ASN B HD22 1 
ATOM   8947  N N    . LEU B 1 248 ? -2.448  52.547  49.395 1.00 8.91  ?  214  LEU B N    1 
ATOM   8948  C CA   . LEU B 1 248 ? -2.527  51.288  50.130 1.00 9.46  ?  214  LEU B CA   1 
ATOM   8949  C C    . LEU B 1 248 ? -1.754  50.175  49.429 1.00 8.90  ?  214  LEU B C    1 
ATOM   8950  O O    . LEU B 1 248 ? -1.805  50.036  48.208 1.00 9.47  ?  214  LEU B O    1 
ATOM   8951  C CB   . LEU B 1 248 ? -3.977  50.854  50.315 1.00 8.74  ?  214  LEU B CB   1 
ATOM   8952  C CG   . LEU B 1 248 ? -4.838  51.754  51.210 1.00 9.35  ?  214  LEU B CG   1 
ATOM   8953  C CD1  . LEU B 1 248 ? -6.276  51.290  51.168 1.00 11.35 ?  214  LEU B CD1  1 
ATOM   8954  C CD2  . LEU B 1 248 ? -4.302  51.758  52.640 1.00 11.95 ?  214  LEU B CD2  1 
ATOM   8955  H H    . LEU B 1 248 ? -2.894  52.542  48.659 1.00 10.69 ?  214  LEU B H    1 
ATOM   8956  H HA   . LEU B 1 248 ? -2.117  51.421  50.999 1.00 11.35 ?  214  LEU B HA   1 
ATOM   8957  H HB2  . LEU B 1 248 ? -4.398  50.829  49.442 1.00 10.49 ?  214  LEU B HB2  1 
ATOM   8958  H HB3  . LEU B 1 248 ? -3.979  49.969  50.711 1.00 10.49 ?  214  LEU B HB3  1 
ATOM   8959  H HG   . LEU B 1 248 ? -4.805  52.668  50.885 1.00 11.22 ?  214  LEU B HG   1 
ATOM   8960  H HD11 . LEU B 1 248 ? -6.798  51.821  51.789 1.00 13.61 ?  214  LEU B HD11 1 
ATOM   8961  H HD12 . LEU B 1 248 ? -6.618  51.403  50.267 1.00 13.61 ?  214  LEU B HD12 1 
ATOM   8962  H HD13 . LEU B 1 248 ? -6.313  50.354  51.420 1.00 13.61 ?  214  LEU B HD13 1 
ATOM   8963  H HD21 . LEU B 1 248 ? -4.935  52.217  53.213 1.00 14.34 ?  214  LEU B HD21 1 
ATOM   8964  H HD22 . LEU B 1 248 ? -4.189  50.842  52.937 1.00 14.34 ?  214  LEU B HD22 1 
ATOM   8965  H HD23 . LEU B 1 248 ? -3.448  52.219  52.655 1.00 14.34 ?  214  LEU B HD23 1 
ATOM   8966  N N    . ILE B 1 249 ? -1.053  49.373  50.222 1.00 8.70  ?  215  ILE B N    1 
ATOM   8967  C CA   . ILE B 1 249 ? -0.393  48.166  49.733 1.00 9.41  ?  215  ILE B CA   1 
ATOM   8968  C C    . ILE B 1 249 ? -0.903  47.003  50.575 1.00 8.92  ?  215  ILE B C    1 
ATOM   8969  O O    . ILE B 1 249 ? -0.625  46.936  51.778 1.00 9.78  ?  215  ILE B O    1 
ATOM   8970  C CB   . ILE B 1 249 ? 1.138   48.243  49.810 1.00 9.77  ?  215  ILE B CB   1 
ATOM   8971  C CG1  . ILE B 1 249 ? 1.677   49.606  49.358 1.00 11.62 ?  215  ILE B CG1  1 
ATOM   8972  C CG2  . ILE B 1 249 ? 1.736   47.094  48.989 1.00 11.07 ?  215  ILE B CG2  1 
ATOM   8973  C CD1  . ILE B 1 249 ? 3.166   49.740  49.603 1.00 13.96 ?  215  ILE B CD1  1 
ATOM   8974  H H    . ILE B 1 249 ? -0.943  49.510  51.064 1.00 10.44 ?  215  ILE B H    1 
ATOM   8975  H HA   . ILE B 1 249 ? -0.645  48.033  48.806 1.00 11.30 ?  215  ILE B HA   1 
ATOM   8976  H HB   . ILE B 1 249 ? 1.405   48.149  50.737 1.00 11.72 ?  215  ILE B HB   1 
ATOM   8977  H HG12 . ILE B 1 249 ? 1.516   49.712  48.407 1.00 13.95 ?  215  ILE B HG12 1 
ATOM   8978  H HG13 . ILE B 1 249 ? 1.224   50.307  49.852 1.00 13.95 ?  215  ILE B HG13 1 
ATOM   8979  H HG21 . ILE B 1 249 ? 2.699   47.091  49.106 1.00 13.28 ?  215  ILE B HG21 1 
ATOM   8980  H HG22 . ILE B 1 249 ? 1.362   46.255  49.301 1.00 13.28 ?  215  ILE B HG22 1 
ATOM   8981  H HG23 . ILE B 1 249 ? 1.517   47.227  48.054 1.00 13.28 ?  215  ILE B HG23 1 
ATOM   8982  H HD11 . ILE B 1 249 ? 3.439   50.649  49.400 1.00 16.75 ?  215  ILE B HD11 1 
ATOM   8983  H HD12 . ILE B 1 249 ? 3.352   49.540  50.534 1.00 16.75 ?  215  ILE B HD12 1 
ATOM   8984  H HD13 . ILE B 1 249 ? 3.638   49.117  49.030 1.00 16.75 ?  215  ILE B HD13 1 
ATOM   8985  N N    . LEU B 1 250 ? -1.644  46.088  49.959 1.00 8.94  ?  216  LEU B N    1 
ATOM   8986  C CA   . LEU B 1 250 ? -2.109  44.868  50.611 1.00 8.44  ?  216  LEU B CA   1 
ATOM   8987  C C    . LEU B 1 250 ? -1.356  43.699  49.990 1.00 9.40  ?  216  LEU B C    1 
ATOM   8988  O O    . LEU B 1 250 ? -1.203  43.655  48.775 1.00 11.47 ?  216  LEU B O    1 
ATOM   8989  C CB   . LEU B 1 250 ? -3.604  44.728  50.354 1.00 8.81  ?  216  LEU B CB   1 
ATOM   8990  C CG   . LEU B 1 250 ? -4.356  43.585  51.022 1.00 12.69 ?  216  LEU B CG   1 
ATOM   8991  C CD1  . LEU B 1 250 ? -4.422  43.753  52.501 1.00 14.57 ?  216  LEU B CD1  1 
ATOM   8992  C CD2  . LEU B 1 250 ? -5.743  43.482  50.433 1.00 15.61 ?  216  LEU B CD2  1 
ATOM   8993  H H    . LEU B 1 250 ? -1.898  46.153  49.140 1.00 10.72 ?  216  LEU B H    1 
ATOM   8994  H HA   . LEU B 1 250 ? -1.950  44.868  51.568 1.00 10.12 ?  216  LEU B HA   1 
ATOM   8995  H HB2  . LEU B 1 250 ? -4.029  45.548  50.651 1.00 10.57 ?  216  LEU B HB2  1 
ATOM   8996  H HB3  . LEU B 1 250 ? -3.726  44.617  49.398 1.00 10.57 ?  216  LEU B HB3  1 
ATOM   8997  H HG   . LEU B 1 250 ? -3.878  42.757  50.857 1.00 15.23 ?  216  LEU B HG   1 
ATOM   8998  H HD11 . LEU B 1 250 ? -4.858  42.978  52.887 1.00 17.48 ?  216  LEU B HD11 1 
ATOM   8999  H HD12 . LEU B 1 250 ? -3.521  43.834  52.850 1.00 17.48 ?  216  LEU B HD12 1 
ATOM   9000  H HD13 . LEU B 1 250 ? -4.929  44.554  52.705 1.00 17.48 ?  216  LEU B HD13 1 
ATOM   9001  H HD21 . LEU B 1 250 ? -6.290  42.924  51.008 1.00 18.74 ?  216  LEU B HD21 1 
ATOM   9002  H HD22 . LEU B 1 250 ? -6.127  44.371  50.371 1.00 18.74 ?  216  LEU B HD22 1 
ATOM   9003  H HD23 . LEU B 1 250 ? -5.682  43.086  49.549 1.00 18.74 ?  216  LEU B HD23 1 
ATOM   9004  N N    . ALA B 1 251 ? -0.873  42.754  50.798 1.00 8.95  ?  217  ALA B N    1 
ATOM   9005  C CA   . ALA B 1 251 ? -0.085  41.648  50.265 1.00 8.46  ?  217  ALA B CA   1 
ATOM   9006  C C    . ALA B 1 251 ? -0.646  40.302  50.705 1.00 9.41  ?  217  ALA B C    1 
ATOM   9007  O O    . ALA B 1 251 ? -1.158  40.155  51.813 1.00 9.52  ?  217  ALA B O    1 
ATOM   9008  C CB   . ALA B 1 251 ? 1.381   41.735  50.739 1.00 9.36  ?  217  ALA B CB   1 
ATOM   9009  H H    . ALA B 1 251 ? -0.989  42.735  51.650 1.00 10.74 ?  217  ALA B H    1 
ATOM   9010  H HA   . ALA B 1 251 ? -0.128  41.687  49.297 1.00 10.15 ?  217  ALA B HA   1 
ATOM   9011  H HB1  . ALA B 1 251 ? 1.854   40.940  50.448 1.00 11.23 ?  217  ALA B HB1  1 
ATOM   9012  H HB2  . ALA B 1 251 ? 1.791   42.524  50.353 1.00 11.23 ?  217  ALA B HB2  1 
ATOM   9013  H HB3  . ALA B 1 251 ? 1.397   41.793  51.707 1.00 11.23 ?  217  ALA B HB3  1 
ATOM   9014  N N    . ASN B 1 252 ? -0.518  39.302  49.829 1.00 9.05  ?  218  ASN B N    1 
ATOM   9015  C CA   . ASN B 1 252 ? -0.850  37.912  50.158 1.00 8.16  ?  218  ASN B CA   1 
ATOM   9016  C C    . ASN B 1 252 ? 0.373   37.362  50.884 1.00 7.04  ?  218  ASN B C    1 
ATOM   9017  O O    . ASN B 1 252 ? 1.312   36.859  50.260 1.00 8.26  ?  218  ASN B O    1 
ATOM   9018  C CB   . ASN B 1 252 ? -1.155  37.174  48.861 1.00 7.74  ?  218  ASN B CB   1 
ATOM   9019  C CG   . ASN B 1 252 ? -1.575  35.737  49.063 1.00 7.91  ?  218  ASN B CG   1 
ATOM   9020  O OD1  . ASN B 1 252 ? -1.712  35.251  50.182 1.00 8.42  ?  218  ASN B OD1  1 
ATOM   9021  N ND2  . ASN B 1 252 ? -1.809  35.056  47.946 1.00 8.21  ?  218  ASN B ND2  1 
ATOM   9022  H H    . ASN B 1 252 ? -0.236  39.405  49.023 1.00 10.86 ?  218  ASN B H    1 
ATOM   9023  H HA   . ASN B 1 252 ? -1.620  37.830  50.742 1.00 9.79  ?  218  ASN B HA   1 
ATOM   9024  H HB2  . ASN B 1 252 ? -1.878  37.631  48.404 1.00 9.29  ?  218  ASN B HB2  1 
ATOM   9025  H HB3  . ASN B 1 252 ? -0.359  37.174  48.307 1.00 9.29  ?  218  ASN B HB3  1 
ATOM   9026  H HD21 . ASN B 1 252 ? -2.052  34.232  47.987 1.00 9.85  ?  218  ASN B HD21 1 
ATOM   9027  H HD22 . ASN B 1 252 ? -1.717  35.439  47.181 1.00 9.85  ?  218  ASN B HD22 1 
ATOM   9028  N N    . ILE B 1 253 ? 0.404   37.522  52.217 1.00 8.78  ?  219  ILE B N    1 
ATOM   9029  C CA   . ILE B 1 253 ? 1.630   37.257  52.975 1.00 8.91  ?  219  ILE B CA   1 
ATOM   9030  C C    . ILE B 1 253 ? 1.473   36.449  54.253 1.00 8.53  ?  219  ILE B C    1 
ATOM   9031  O O    . ILE B 1 253 ? 2.311   35.582  54.517 1.00 9.35  ?  219  ILE B O    1 
ATOM   9032  C CB   . ILE B 1 253 ? 2.424   38.564  53.213 1.00 9.54  ?  219  ILE B CB   1 
ATOM   9033  C CG1  . ILE B 1 253 ? 3.804   38.271  53.815 1.00 10.29 ?  219  ILE B CG1  1 
ATOM   9034  C CG2  . ILE B 1 253 ? 1.668   39.551  54.092 1.00 10.17 ?  219  ILE B CG2  1 
ATOM   9035  C CD1  . ILE B 1 253 ? 4.692   37.467  52.932 1.00 13.20 ?  219  ILE B CD1  1 
ATOM   9036  H H    . ILE B 1 253 ? -0.263  37.779  52.695 1.00 10.54 ?  219  ILE B H    1 
ATOM   9037  H HA   . ILE B 1 253 ? 2.132   36.647  52.411 1.00 10.69 ?  219  ILE B HA   1 
ATOM   9038  H HB   . ILE B 1 253 ? 2.541   38.973  52.341 1.00 11.45 ?  219  ILE B HB   1 
ATOM   9039  H HG12 . ILE B 1 253 ? 4.250   39.114  53.994 1.00 12.35 ?  219  ILE B HG12 1 
ATOM   9040  H HG13 . ILE B 1 253 ? 3.684   37.778  54.641 1.00 12.35 ?  219  ILE B HG13 1 
ATOM   9041  H HG21 . ILE B 1 253 ? 2.062   40.431  53.989 1.00 12.20 ?  219  ILE B HG21 1 
ATOM   9042  H HG22 . ILE B 1 253 ? 0.738   39.570  53.817 1.00 12.20 ?  219  ILE B HG22 1 
ATOM   9043  H HG23 . ILE B 1 253 ? 1.734   39.265  55.017 1.00 12.20 ?  219  ILE B HG23 1 
ATOM   9044  H HD11 . ILE B 1 253 ? 5.615   37.615  53.192 1.00 15.84 ?  219  ILE B HD11 1 
ATOM   9045  H HD12 . ILE B 1 253 ? 4.468   36.528  53.030 1.00 15.84 ?  219  ILE B HD12 1 
ATOM   9046  H HD13 . ILE B 1 253 ? 4.559   37.744  52.012 1.00 15.84 ?  219  ILE B HD13 1 
ATOM   9047  N N    . ILE B 1 254 ? 0.446   36.698  55.058 1.00 8.48  ?  220  ILE B N    1 
ATOM   9048  C CA   . ILE B 1 254 ? 0.286   35.891  56.271 1.00 8.33  ?  220  ILE B CA   1 
ATOM   9049  C C    . ILE B 1 254 ? -0.170  34.492  55.876 1.00 8.42  ?  220  ILE B C    1 
ATOM   9050  O O    . ILE B 1 254 ? -1.182  34.324  55.182 1.00 8.65  ?  220  ILE B O    1 
ATOM   9051  C CB   . ILE B 1 254 ? -0.697  36.541  57.251 1.00 8.26  ?  220  ILE B CB   1 
ATOM   9052  C CG1  . ILE B 1 254 ? -0.108  37.835  57.818 1.00 9.19  ?  220  ILE B CG1  1 
ATOM   9053  C CG2  . ILE B 1 254 ? -1.047  35.552  58.364 1.00 9.55  ?  220  ILE B CG2  1 
ATOM   9054  C CD1  . ILE B 1 254 ? -1.050  38.607  58.740 1.00 11.85 ?  220  ILE B CD1  1 
ATOM   9055  H H    . ILE B 1 254 ? -0.152  37.303  54.933 1.00 10.17 ?  220  ILE B H    1 
ATOM   9056  H HA   . ILE B 1 254 ? 1.144   35.829  56.719 1.00 9.99  ?  220  ILE B HA   1 
ATOM   9057  H HB   . ILE B 1 254 ? -1.512  36.772  56.779 1.00 9.91  ?  220  ILE B HB   1 
ATOM   9058  H HG12 . ILE B 1 254 ? 0.687   37.616  58.329 1.00 11.03 ?  220  ILE B HG12 1 
ATOM   9059  H HG13 . ILE B 1 254 ? 0.123   38.420  57.080 1.00 11.03 ?  220  ILE B HG13 1 
ATOM   9060  H HG21 . ILE B 1 254 ? -1.601  36.000  59.022 1.00 11.46 ?  220  ILE B HG21 1 
ATOM   9061  H HG22 . ILE B 1 254 ? -1.529  34.803  57.980 1.00 11.46 ?  220  ILE B HG22 1 
ATOM   9062  H HG23 . ILE B 1 254 ? -0.227  35.240  58.779 1.00 11.46 ?  220  ILE B HG23 1 
ATOM   9063  H HD11 . ILE B 1 254 ? -0.705  39.505  58.864 1.00 14.22 ?  220  ILE B HD11 1 
ATOM   9064  H HD12 . ILE B 1 254 ? -1.930  38.644  58.334 1.00 14.22 ?  220  ILE B HD12 1 
ATOM   9065  H HD13 . ILE B 1 254 ? -1.099  38.151  59.595 1.00 14.22 ?  220  ILE B HD13 1 
ATOM   9066  N N    . ARG B 1 255 ? 0.541   33.480  56.356 1.00 8.90  ?  221  ARG B N    1 
ATOM   9067  C CA   . ARG B 1 255 ? 0.339   32.101  55.939 1.00 7.92  ?  221  ARG B CA   1 
ATOM   9068  C C    . ARG B 1 255 ? 1.129   31.199  56.871 1.00 9.06  ?  221  ARG B C    1 
ATOM   9069  O O    . ARG B 1 255 ? 2.329   31.408  57.100 1.00 9.17  ?  221  ARG B O    1 
ATOM   9070  C CB   . ARG B 1 255 ? 0.852   31.914  54.514 1.00 8.33  ?  221  ARG B CB   1 
ATOM   9071  C CG   . ARG B 1 255 ? 0.531   30.555  53.885 1.00 9.41  ?  221  ARG B CG   1 
ATOM   9072  C CD   . ARG B 1 255 ? -0.866  30.522  53.295 1.00 8.53  ?  221  ARG B CD   1 
ATOM   9073  N NE   . ARG B 1 255 ? -1.053  31.507  52.232 1.00 9.31  ?  221  ARG B NE   1 
ATOM   9074  C CZ   . ARG B 1 255 ? -0.571  31.372  51.006 1.00 9.37  ?  221  ARG B CZ   1 
ATOM   9075  N NH1  . ARG B 1 255 ? 0.144   30.318  50.660 1.00 9.54  ?  221  ARG B NH1  1 
ATOM   9076  N NH2  . ARG B 1 255 ? -0.801  32.316  50.102 1.00 8.43  ?  221  ARG B NH2  1 
ATOM   9077  H H    . ARG B 1 255 ? 1.165   33.569  56.941 1.00 10.68 ?  221  ARG B H    1 
ATOM   9078  H HA   . ARG B 1 255 ? -0.603  31.872  55.963 1.00 9.50  ?  221  ARG B HA   1 
ATOM   9079  H HB2  . ARG B 1 255 ? 0.454   32.596  53.952 1.00 9.99  ?  221  ARG B HB2  1 
ATOM   9080  H HB3  . ARG B 1 255 ? 1.817   32.011  54.520 1.00 9.99  ?  221  ARG B HB3  1 
ATOM   9081  H HG2  . ARG B 1 255 ? 1.166   30.374  53.174 1.00 11.30 ?  221  ARG B HG2  1 
ATOM   9082  H HG3  . ARG B 1 255 ? 0.590   29.866  54.565 1.00 11.30 ?  221  ARG B HG3  1 
ATOM   9083  H HD2  . ARG B 1 255 ? -1.030  29.642  52.921 1.00 10.23 ?  221  ARG B HD2  1 
ATOM   9084  H HD3  . ARG B 1 255 ? -1.510  30.710  53.995 1.00 10.23 ?  221  ARG B HD3  1 
ATOM   9085  H HE   . ARG B 1 255 ? -1.503  32.217  52.413 1.00 11.17 ?  221  ARG B HE   1 
ATOM   9086  H HH11 . ARG B 1 255 ? 0.306   29.700  51.236 1.00 11.45 ?  221  ARG B HH11 1 
ATOM   9087  H HH12 . ARG B 1 255 ? 0.449   30.249  49.859 1.00 11.45 ?  221  ARG B HH12 1 
ATOM   9088  H HH21 . ARG B 1 255 ? -1.261  33.011  50.314 1.00 10.12 ?  221  ARG B HH21 1 
ATOM   9089  H HH22 . ARG B 1 255 ? -0.489  32.233  49.305 1.00 10.12 ?  221  ARG B HH22 1 
ATOM   9090  N N    . VAL B 1 256 ? 0.484   30.159  57.380 1.00 9.43  ?  222  VAL B N    1 
ATOM   9091  C CA   . VAL B 1 256 ? 1.214   29.177  58.172 1.00 9.75  ?  222  VAL B CA   1 
ATOM   9092  C C    . VAL B 1 256 ? 2.197   28.456  57.254 1.00 9.59  ?  222  VAL B C    1 
ATOM   9093  O O    . VAL B 1 256 ? 1.816   27.880  56.227 1.00 9.44  ?  222  VAL B O    1 
ATOM   9094  C CB   . VAL B 1 256 ? 0.257   28.201  58.862 1.00 9.29  ?  222  VAL B CB   1 
ATOM   9095  C CG1  . VAL B 1 256 ? 1.049   27.041  59.513 1.00 12.47 ?  222  VAL B CG1  1 
ATOM   9096  C CG2  . VAL B 1 256 ? -0.591  28.905  59.889 1.00 11.50 ?  222  VAL B CG2  1 
ATOM   9097  H H    . VAL B 1 256 ? -0.356  30.002  57.285 1.00 11.31 ?  222  VAL B H    1 
ATOM   9098  H HA   . VAL B 1 256 ? 1.719   29.629  58.865 1.00 11.70 ?  222  VAL B HA   1 
ATOM   9099  H HB   . VAL B 1 256 ? -0.339  27.831  58.193 1.00 11.15 ?  222  VAL B HB   1 
ATOM   9100  H HG11 . VAL B 1 256 ? 0.457   26.545  60.100 1.00 14.96 ?  222  VAL B HG11 1 
ATOM   9101  H HG12 . VAL B 1 256 ? 1.386   26.458  58.814 1.00 14.96 ?  222  VAL B HG12 1 
ATOM   9102  H HG13 . VAL B 1 256 ? 1.788   27.409  60.022 1.00 14.96 ?  222  VAL B HG13 1 
ATOM   9103  H HG21 . VAL B 1 256 ? -1.180  28.258  60.309 1.00 13.80 ?  222  VAL B HG21 1 
ATOM   9104  H HG22 . VAL B 1 256 ? -0.012  29.306  60.556 1.00 13.80 ?  222  VAL B HG22 1 
ATOM   9105  H HG23 . VAL B 1 256 ? -1.115  29.592  59.449 1.00 13.80 ?  222  VAL B HG23 1 
ATOM   9106  N N    . ARG B 1 257 ? 3.484   28.504  57.613 1.00 8.30  ?  223  ARG B N    1 
ATOM   9107  C CA   . ARG B 1 257 ? 4.568   27.943  56.806 1.00 9.81  ?  223  ARG B CA   1 
ATOM   9108  C C    . ARG B 1 257 ? 5.656   27.461  57.762 1.00 8.27  ?  223  ARG B C    1 
ATOM   9109  O O    . ARG B 1 257 ? 6.067   28.239  58.640 1.00 9.76  ?  223  ARG B O    1 
ATOM   9110  C CB   . ARG B 1 257 ? 5.222   28.962  55.862 1.00 10.37 ?  223  ARG B CB   1 
ATOM   9111  C CG   . ARG B 1 257 ? 4.377   29.517  54.718 1.00 9.66  ?  223  ARG B CG   1 
ATOM   9112  C CD   . ARG B 1 257 ? 3.956   28.467  53.723 1.00 10.07 ?  223  ARG B CD   1 
ATOM   9113  N NE   . ARG B 1 257 ? 5.032   27.582  53.300 1.00 9.92  ?  223  ARG B NE   1 
ATOM   9114  C CZ   . ARG B 1 257 ? 4.887   26.649  52.374 1.00 10.40 ?  223  ARG B CZ   1 
ATOM   9115  N NH1  . ARG B 1 257 ? 3.752   26.518  51.709 1.00 11.49 ?  223  ARG B NH1  1 
ATOM   9116  N NH2  . ARG B 1 257 ? 5.885   25.799  52.143 1.00 10.28 ?  223  ARG B NH2  1 
ATOM   9117  H H    . ARG B 1 257 ? 3.762   28.868  58.341 1.00 9.96  ?  223  ARG B H    1 
ATOM   9118  H HA   . ARG B 1 257 ? 4.196   27.212  56.288 1.00 11.77 ?  223  ARG B HA   1 
ATOM   9119  H HB2  . ARG B 1 257 ? 5.503   29.722  56.396 1.00 12.44 ?  223  ARG B HB2  1 
ATOM   9120  H HB3  . ARG B 1 257 ? 5.994   28.537  55.457 1.00 12.44 ?  223  ARG B HB3  1 
ATOM   9121  H HG2  . ARG B 1 257 ? 3.573   29.917  55.086 1.00 11.59 ?  223  ARG B HG2  1 
ATOM   9122  H HG3  . ARG B 1 257 ? 4.893   30.187  54.242 1.00 11.59 ?  223  ARG B HG3  1 
ATOM   9123  H HD2  . ARG B 1 257 ? 3.264   27.918  54.124 1.00 12.09 ?  223  ARG B HD2  1 
ATOM   9124  H HD3  . ARG B 1 257 ? 3.611   28.909  52.931 1.00 12.09 ?  223  ARG B HD3  1 
ATOM   9125  H HE   . ARG B 1 257 ? 5.802   27.670  53.672 1.00 11.90 ?  223  ARG B HE   1 
ATOM   9126  H HH11 . ARG B 1 257 ? 3.093   27.045  51.875 1.00 13.79 ?  223  ARG B HH11 1 
ATOM   9127  H HH12 . ARG B 1 257 ? 3.673   25.907  51.109 1.00 13.79 ?  223  ARG B HH12 1 
ATOM   9128  H HH21 . ARG B 1 257 ? 6.615   25.860  52.593 1.00 12.33 ?  223  ARG B HH21 1 
ATOM   9129  H HH22 . ARG B 1 257 ? 5.800   25.189  51.542 1.00 12.33 ?  223  ARG B HH22 1 
ATOM   9130  N N    . PRO B 1 258 ? 6.215   26.261  57.567 1.00 9.41  ?  224  PRO B N    1 
ATOM   9131  C CA   . PRO B 1 258 ? 7.371   25.883  58.407 1.00 8.55  ?  224  PRO B CA   1 
ATOM   9132  C C    . PRO B 1 258 ? 8.565   26.793  58.240 1.00 12.85 ?  224  PRO B C    1 
ATOM   9133  O O    . PRO B 1 258 ? 9.376   26.934  59.165 1.00 11.73 ?  224  PRO B O    1 
ATOM   9134  C CB   . PRO B 1 258 ? 7.678   24.438  58.005 1.00 11.37 ?  224  PRO B CB   1 
ATOM   9135  C CG   . PRO B 1 258 ? 6.899   24.168  56.799 1.00 17.07 ?  224  PRO B CG   1 
ATOM   9136  C CD   . PRO B 1 258 ? 5.789   25.177  56.672 1.00 9.49  ?  224  PRO B CD   1 
ATOM   9137  H HA   . PRO B 1 258 ? 7.101   25.883  59.338 1.00 10.26 ?  224  PRO B HA   1 
ATOM   9138  H HB2  . PRO B 1 258 ? 8.627   24.346  57.825 1.00 13.65 ?  224  PRO B HB2  1 
ATOM   9139  H HB3  . PRO B 1 258 ? 7.417   23.839  58.722 1.00 13.65 ?  224  PRO B HB3  1 
ATOM   9140  H HG2  . PRO B 1 258 ? 7.486   24.226  56.030 1.00 20.49 ?  224  PRO B HG2  1 
ATOM   9141  H HG3  . PRO B 1 258 ? 6.525   23.275  56.865 1.00 20.49 ?  224  PRO B HG3  1 
ATOM   9142  H HD2  . PRO B 1 258 ? 5.713   25.493  55.758 1.00 11.39 ?  224  PRO B HD2  1 
ATOM   9143  H HD3  . PRO B 1 258 ? 4.944   24.800  56.964 1.00 11.39 ?  224  PRO B HD3  1 
ATOM   9144  N N    . GLU B 1 259 ? 8.700   27.418  57.077 1.00 10.85 ?  225  GLU B N    1 
ATOM   9145  C CA   . GLU B 1 259 ? 9.813   28.309  56.792 1.00 10.99 ?  225  GLU B CA   1 
ATOM   9146  C C    . GLU B 1 259 ? 9.699   29.656  57.488 1.00 10.41 ?  225  GLU B C    1 
ATOM   9147  O O    . GLU B 1 259 ? 10.693  30.388  57.539 1.00 13.28 ?  225  GLU B O    1 
ATOM   9148  C CB   . GLU B 1 259 ? 9.881   28.546  55.277 1.00 13.23 ?  225  GLU B CB   1 
ATOM   9149  C CG   . GLU B 1 259 ? 10.003  27.270  54.462 1.00 13.00 ?  225  GLU B CG   1 
ATOM   9150  C CD   . GLU B 1 259 ? 8.671   26.650  54.045 1.00 12.32 ?  225  GLU B CD   1 
ATOM   9151  O OE1  . GLU B 1 259 ? 7.606   27.092  54.515 1.00 11.57 ?  225  GLU B OE1  1 
ATOM   9152  O OE2  . GLU B 1 259 ? 8.696   25.673  53.262 1.00 14.43 ?  225  GLU B OE2  1 
ATOM   9153  H H    . GLU B 1 259 ? 8.149   27.341  56.421 1.00 13.02 ?  225  GLU B H    1 
ATOM   9154  H HA   . GLU B 1 259 ? 10.630  27.887  57.102 1.00 13.19 ?  225  GLU B HA   1 
ATOM   9155  H HB2  . GLU B 1 259 ? 9.071   29.000  54.996 1.00 15.88 ?  225  GLU B HB2  1 
ATOM   9156  H HB3  . GLU B 1 259 ? 10.655  29.097  55.082 1.00 15.88 ?  225  GLU B HB3  1 
ATOM   9157  H HG2  . GLU B 1 259 ? 10.500  27.467  53.653 1.00 15.60 ?  225  GLU B HG2  1 
ATOM   9158  H HG3  . GLU B 1 259 ? 10.478  26.610  54.991 1.00 15.60 ?  225  GLU B HG3  1 
ATOM   9159  N N    . PHE B 1 260 ? 8.519   30.021  57.973 1.00 9.22  ?  226  PHE B N    1 
ATOM   9160  C CA   . PHE B 1 260 ? 8.261   31.335  58.554 1.00 10.50 ?  226  PHE B CA   1 
ATOM   9161  C C    . PHE B 1 260 ? 7.982   31.137  60.044 1.00 10.58 ?  226  PHE B C    1 
ATOM   9162  O O    . PHE B 1 260 ? 6.875   30.758  60.425 1.00 9.92  ?  226  PHE B O    1 
ATOM   9163  C CB   . PHE B 1 260 ? 7.004   31.993  57.955 1.00 10.99 ?  226  PHE B CB   1 
ATOM   9164  C CG   . PHE B 1 260 ? 7.017   32.272  56.455 1.00 12.37 ?  226  PHE B CG   1 
ATOM   9165  C CD1  . PHE B 1 260 ? 8.139   32.145  55.671 1.00 12.03 ?  226  PHE B CD1  1 
ATOM   9166  C CD2  . PHE B 1 260 ? 5.836   32.699  55.867 1.00 11.01 ?  226  PHE B CD2  1 
ATOM   9167  C CE1  . PHE B 1 260 ? 8.070   32.432  54.284 1.00 12.46 ?  226  PHE B CE1  1 
ATOM   9168  C CE2  . PHE B 1 260 ? 5.766   32.983  54.504 1.00 13.89 ?  226  PHE B CE2  1 
ATOM   9169  C CZ   . PHE B 1 260 ? 6.874   32.823  53.719 1.00 12.41 ?  226  PHE B CZ   1 
ATOM   9170  H H    . PHE B 1 260 ? 7.829   29.508  57.977 1.00 11.07 ?  226  PHE B H    1 
ATOM   9171  H HA   . PHE B 1 260 ? 9.047   31.881  58.394 1.00 12.60 ?  226  PHE B HA   1 
ATOM   9172  H HB2  . PHE B 1 260 ? 6.249   31.407  58.127 1.00 13.18 ?  226  PHE B HB2  1 
ATOM   9173  H HB3  . PHE B 1 260 ? 6.870   32.844  58.400 1.00 13.18 ?  226  PHE B HB3  1 
ATOM   9174  H HD1  . PHE B 1 260 ? 8.943   31.870  56.050 1.00 14.43 ?  226  PHE B HD1  1 
ATOM   9175  H HD2  . PHE B 1 260 ? 5.075   32.798  56.393 1.00 13.22 ?  226  PHE B HD2  1 
ATOM   9176  H HE1  . PHE B 1 260 ? 8.832   32.356  53.755 1.00 14.95 ?  226  PHE B HE1  1 
ATOM   9177  H HE2  . PHE B 1 260 ? 4.968   33.281  54.130 1.00 16.67 ?  226  PHE B HE2  1 
ATOM   9178  H HZ   . PHE B 1 260 ? 6.822   32.978  52.803 1.00 14.89 ?  226  PHE B HZ   1 
ATOM   9179  N N    . GLU B 1 261 ? 8.960   31.455  60.895 1.00 11.36 ?  227  GLU B N    1 
ATOM   9180  C CA   . GLU B 1 261 ? 8.748   31.290  62.331 1.00 11.70 ?  227  GLU B CA   1 
ATOM   9181  C C    . GLU B 1 261 ? 7.560   32.096  62.842 1.00 10.94 ?  227  GLU B C    1 
ATOM   9182  O O    . GLU B 1 261 ? 6.902   31.693  63.810 1.00 11.73 ?  227  GLU B O    1 
ATOM   9183  C CB   . GLU B 1 261 ? 10.013  31.675  63.092 1.00 14.96 ?  227  GLU B CB   1 
ATOM   9184  C CG   . GLU B 1 261 ? 11.102  30.614  63.029 1.00 13.80 ?  227  GLU B CG   1 
ATOM   9185  C CD   . GLU B 1 261 ? 11.878  30.649  61.745 1.00 15.61 ?  227  GLU B CD   1 
ATOM   9186  O OE1  . GLU B 1 261 ? 11.709  31.613  60.957 1.00 16.69 ?  227  GLU B OE1  1 
ATOM   9187  O OE2  . GLU B 1 261 ? 12.686  29.725  61.521 1.00 17.66 ?  227  GLU B OE2  1 
ATOM   9188  H H    . GLU B 1 261 ? 9.733   31.759  60.672 1.00 13.63 ?  227  GLU B H    1 
ATOM   9189  H HA   . GLU B 1 261 ? 8.558   30.355  62.503 1.00 14.04 ?  227  GLU B HA   1 
ATOM   9190  H HB2  . GLU B 1 261 ? 10.371  32.492  62.711 1.00 17.95 ?  227  GLU B HB2  1 
ATOM   9191  H HB3  . GLU B 1 261 ? 9.787   31.814  64.025 1.00 17.95 ?  227  GLU B HB3  1 
ATOM   9192  H HG2  . GLU B 1 261 ? 11.725  30.758  63.758 1.00 16.56 ?  227  GLU B HG2  1 
ATOM   9193  H HG3  . GLU B 1 261 ? 10.694  29.738  63.108 1.00 16.56 ?  227  GLU B HG3  1 
ATOM   9194  N N    . GLU B 1 262 ? 7.246   33.231  62.210 1.00 9.77  ?  228  GLU B N    1 
ATOM   9195  C CA   . GLU B 1 262 ? 6.092   34.033  62.593 1.00 10.72 ?  228  GLU B CA   1 
ATOM   9196  C C    . GLU B 1 262 ? 4.956   33.961  61.575 1.00 10.28 ?  228  GLU B C    1 
ATOM   9197  O O    . GLU B 1 262 ? 4.029   34.776  61.624 1.00 10.47 ?  228  GLU B O    1 
ATOM   9198  C CB   . GLU B 1 262 ? 6.496   35.480  62.848 1.00 11.64 ?  228  GLU B CB   1 
ATOM   9199  C CG   . GLU B 1 262 ? 7.584   35.666  63.888 1.00 14.04 ?  228  GLU B CG   1 
ATOM   9200  C CD   . GLU B 1 262 ? 7.995   37.118  64.008 1.00 20.35 ?  228  GLU B CD   1 
ATOM   9201  O OE1  . GLU B 1 262 ? 7.177   37.921  64.494 1.00 27.16 ?  228  GLU B OE1  1 
ATOM   9202  O OE2  . GLU B 1 262 ? 9.119   37.438  63.580 1.00 30.47 ?  228  GLU B OE2  1 
ATOM   9203  H H    . GLU B 1 262 ? 7.694   33.556  61.551 1.00 11.73 ?  228  GLU B H    1 
ATOM   9204  H HA   . GLU B 1 262 ? 5.751   33.676  63.427 1.00 12.87 ?  228  GLU B HA   1 
ATOM   9205  H HB2  . GLU B 1 262 ? 6.820   35.859  62.016 1.00 13.97 ?  228  GLU B HB2  1 
ATOM   9206  H HB3  . GLU B 1 262 ? 5.715   35.967  63.153 1.00 13.97 ?  228  GLU B HB3  1 
ATOM   9207  H HG2  . GLU B 1 262 ? 7.257   35.369  64.751 1.00 16.85 ?  228  GLU B HG2  1 
ATOM   9208  H HG3  . GLU B 1 262 ? 8.364   35.148  63.633 1.00 16.85 ?  228  GLU B HG3  1 
ATOM   9209  N N    . ASN B 1 263 ? 4.977   32.972  60.682 1.00 9.27  ?  229  ASN B N    1 
ATOM   9210  C CA   . ASN B 1 263 ? 3.858   32.718  59.777 1.00 9.81  ?  229  ASN B CA   1 
ATOM   9211  C C    . ASN B 1 263 ? 3.489   33.942  58.950 1.00 9.91  ?  229  ASN B C    1 
ATOM   9212  O O    . ASN B 1 263 ? 2.309   34.189  58.661 1.00 9.60  ?  229  ASN B O    1 
ATOM   9213  C CB   . ASN B 1 263 ? 2.677   32.112  60.533 1.00 9.49  ?  229  ASN B CB   1 
ATOM   9214  C CG   . ASN B 1 263 ? 2.998   30.710  61.029 1.00 9.57  ?  229  ASN B CG   1 
ATOM   9215  O OD1  . ASN B 1 263 ? 3.680   29.953  60.334 1.00 10.27 ?  229  ASN B OD1  1 
ATOM   9216  N ND2  . ASN B 1 263 ? 2.552   30.381  62.248 1.00 11.62 ?  229  ASN B ND2  1 
ATOM   9217  H H    . ASN B 1 263 ? 5.635   32.429  60.579 1.00 11.12 ?  229  ASN B H    1 
ATOM   9218  H HA   . ASN B 1 263 ? 4.133   32.060  59.119 1.00 11.78 ?  229  ASN B HA   1 
ATOM   9219  H HB2  . ASN B 1 263 ? 2.468   32.668  61.300 1.00 11.39 ?  229  ASN B HB2  1 
ATOM   9220  H HB3  . ASN B 1 263 ? 1.910   32.060  59.942 1.00 11.39 ?  229  ASN B HB3  1 
ATOM   9221  H HD21 . ASN B 1 263 ? 2.711   29.599  62.567 1.00 13.95 ?  229  ASN B HD21 1 
ATOM   9222  H HD22 . ASN B 1 263 ? 2.107   30.953  62.711 1.00 13.95 ?  229  ASN B HD22 1 
ATOM   9223  N N    . GLY B 1 264 ? 4.525   34.688  58.532 1.00 9.89  ?  230  GLY B N    1 
ATOM   9224  C CA   . GLY B 1 264 ? 4.399   35.807  57.621 1.00 9.59  ?  230  GLY B CA   1 
ATOM   9225  C C    . GLY B 1 264 ? 4.457   37.174  58.269 1.00 11.42 ?  230  GLY B C    1 
ATOM   9226  O O    . GLY B 1 264 ? 4.695   38.161  57.562 1.00 11.41 ?  230  GLY B O    1 
ATOM   9227  H H    . GLY B 1 264 ? 5.337   34.550  58.779 1.00 11.87 ?  230  GLY B H    1 
ATOM   9228  H HA2  . GLY B 1 264 ? 5.116   35.758  56.970 1.00 11.51 ?  230  GLY B HA2  1 
ATOM   9229  H HA3  . GLY B 1 264 ? 3.548   35.735  57.159 1.00 11.51 ?  230  GLY B HA3  1 
ATOM   9230  N N    . LEU B 1 265 ? 4.253   37.270  59.586 1.00 10.60 ?  231  LEU B N    1 
ATOM   9231  C CA   . LEU B 1 265 ? 4.348   38.571  60.248 1.00 11.18 ?  231  LEU B CA   1 
ATOM   9232  C C    . LEU B 1 265 ? 5.720   39.192  60.068 1.00 12.42 ?  231  LEU B C    1 
ATOM   9233  O O    . LEU B 1 265 ? 5.860   40.425  60.070 1.00 13.27 ?  231  LEU B O    1 
ATOM   9234  C CB   . LEU B 1 265 ? 4.098   38.457  61.746 1.00 11.81 ?  231  LEU B CB   1 
ATOM   9235  C CG   . LEU B 1 265 ? 2.725   37.993  62.142 1.00 12.11 ?  231  LEU B CG   1 
ATOM   9236  C CD1  . LEU B 1 265 ? 2.594   38.011  63.677 1.00 16.45 ?  231  LEU B CD1  1 
ATOM   9237  C CD2  . LEU B 1 265 ? 1.600   38.849  61.524 1.00 14.27 ?  231  LEU B CD2  1 
ATOM   9238  H H    . LEU B 1 265 ? 4.063   36.612  60.106 1.00 12.71 ?  231  LEU B H    1 
ATOM   9239  H HA   . LEU B 1 265 ? 3.664   39.134  59.852 1.00 13.42 ?  231  LEU B HA   1 
ATOM   9240  H HB2  . LEU B 1 265 ? 4.734   37.824  62.113 1.00 14.17 ?  231  LEU B HB2  1 
ATOM   9241  H HB3  . LEU B 1 265 ? 4.233   39.332  62.144 1.00 14.17 ?  231  LEU B HB3  1 
ATOM   9242  H HG   . LEU B 1 265 ? 2.612   37.090  61.805 1.00 14.53 ?  231  LEU B HG   1 
ATOM   9243  H HD11 . LEU B 1 265 ? 1.706   37.708  63.922 1.00 19.74 ?  231  LEU B HD11 1 
ATOM   9244  H HD12 . LEU B 1 265 ? 3.262   37.419  64.058 1.00 19.74 ?  231  LEU B HD12 1 
ATOM   9245  H HD13 . LEU B 1 265 ? 2.734   38.916  63.995 1.00 19.74 ?  231  LEU B HD13 1 
ATOM   9246  H HD21 . LEU B 1 265 ? 0.756   38.611  61.939 1.00 17.13 ?  231  LEU B HD21 1 
ATOM   9247  H HD22 . LEU B 1 265 ? 1.793   39.787  61.682 1.00 17.13 ?  231  LEU B HD22 1 
ATOM   9248  H HD23 . LEU B 1 265 ? 1.559   38.676  60.570 1.00 17.13 ?  231  LEU B HD23 1 
ATOM   9249  N N    . GLU B 1 266 ? 6.749   38.375  59.925 1.00 11.49 ?  232  GLU B N    1 
ATOM   9250  C CA   . GLU B 1 266 ? 8.085   38.934  59.804 1.00 11.98 ?  232  GLU B CA   1 
ATOM   9251  C C    . GLU B 1 266 ? 8.280   39.727  58.514 1.00 14.42 ?  232  GLU B C    1 
ATOM   9252  O O    . GLU B 1 266 ? 9.269   40.448  58.401 1.00 16.00 ?  232  GLU B O    1 
ATOM   9253  C CB   . GLU B 1 266 ? 9.144   37.836  60.003 1.00 16.36 ?  232  GLU B CB   1 
ATOM   9254  C CG   . GLU B 1 266 ? 9.084   36.655  59.050 1.00 12.74 ?  232  GLU B CG   1 
ATOM   9255  C CD   . GLU B 1 266 ? 8.236   35.508  59.549 1.00 11.61 ?  232  GLU B CD   1 
ATOM   9256  O OE1  . GLU B 1 266 ? 7.000   35.597  59.475 1.00 10.55 ?  232  GLU B OE1  1 
ATOM   9257  O OE2  . GLU B 1 266 ? 8.790   34.482  60.013 1.00 13.74 ?  232  GLU B OE2  1 
ATOM   9258  H H    . GLU B 1 266 ? 6.703   37.517  59.896 1.00 13.79 ?  232  GLU B H    1 
ATOM   9259  H HA   . GLU B 1 266 ? 8.241   39.569  60.521 1.00 14.37 ?  232  GLU B HA   1 
ATOM   9260  H HB2  . GLU B 1 266 ? 10.020  38.239  59.901 1.00 19.63 ?  232  GLU B HB2  1 
ATOM   9261  H HB3  . GLU B 1 266 ? 9.045   37.481  60.901 1.00 19.63 ?  232  GLU B HB3  1 
ATOM   9262  H HG2  . GLU B 1 266 ? 8.710   36.954  58.207 1.00 15.29 ?  232  GLU B HG2  1 
ATOM   9263  H HG3  . GLU B 1 266 ? 9.984   36.319  58.913 1.00 15.29 ?  232  GLU B HG3  1 
ATOM   9264  N N    . TYR B 1 267 ? 7.338   39.673  57.573 1.00 11.71 ?  233  TYR B N    1 
ATOM   9265  C CA   . TYR B 1 267 ? 7.412   40.416  56.323 1.00 13.33 ?  233  TYR B CA   1 
ATOM   9266  C C    . TYR B 1 267 ? 6.368   41.517  56.249 1.00 12.11 ?  233  TYR B C    1 
ATOM   9267  O O    . TYR B 1 267 ? 6.353   42.291  55.279 1.00 13.85 ?  233  TYR B O    1 
ATOM   9268  C CB   . TYR B 1 267 ? 7.205   39.462  55.150 1.00 13.55 ?  233  TYR B CB   1 
ATOM   9269  C CG   . TYR B 1 267 ? 8.105   38.259  55.210 1.00 12.61 ?  233  TYR B CG   1 
ATOM   9270  C CD1  . TYR B 1 267 ? 9.479   38.382  55.066 1.00 13.69 ?  233  TYR B CD1  1 
ATOM   9271  C CD2  . TYR B 1 267 ? 7.583   36.994  55.446 1.00 13.41 ?  233  TYR B CD2  1 
ATOM   9272  C CE1  . TYR B 1 267 ? 10.301  37.256  55.143 1.00 14.56 ?  233  TYR B CE1  1 
ATOM   9273  C CE2  . TYR B 1 267 ? 8.387   35.880  55.497 1.00 16.26 ?  233  TYR B CE2  1 
ATOM   9274  C CZ   . TYR B 1 267 ? 9.740   36.008  55.349 1.00 17.16 ?  233  TYR B CZ   1 
ATOM   9275  O OH   . TYR B 1 267 ? 10.551  34.886  55.425 1.00 20.50 ?  233  TYR B OH   1 
ATOM   9276  H H    . TYR B 1 267 ? 6.624   39.198  57.640 1.00 14.05 ?  233  TYR B H    1 
ATOM   9277  H HA   . TYR B 1 267 ? 8.291   40.817  56.244 1.00 15.99 ?  233  TYR B HA   1 
ATOM   9278  H HB2  . TYR B 1 267 ? 6.287   39.150  55.155 1.00 16.26 ?  233  TYR B HB2  1 
ATOM   9279  H HB3  . TYR B 1 267 ? 7.390   39.934  54.323 1.00 16.26 ?  233  TYR B HB3  1 
ATOM   9280  H HD1  . TYR B 1 267 ? 9.856   39.220  54.917 1.00 16.43 ?  233  TYR B HD1  1 
ATOM   9281  H HD2  . TYR B 1 267 ? 6.667   36.899  55.573 1.00 16.09 ?  233  TYR B HD2  1 
ATOM   9282  H HE1  . TYR B 1 267 ? 11.223  37.344  55.057 1.00 17.47 ?  233  TYR B HE1  1 
ATOM   9283  H HE2  . TYR B 1 267 ? 8.010   35.040  55.632 1.00 19.51 ?  233  TYR B HE2  1 
ATOM   9284  H HH   . TYR B 1 267 ? 11.351  35.099  55.283 1.00 24.60 ?  233  TYR B HH   1 
ATOM   9285  N N    . LEU B 1 268 ? 5.510   41.624  57.242 1.00 10.84 ?  234  LEU B N    1 
ATOM   9286  C CA   . LEU B 1 268 ? 4.355   42.509  57.140 1.00 13.02 ?  234  LEU B CA   1 
ATOM   9287  C C    . LEU B 1 268 ? 4.733   43.983  57.220 1.00 15.42 ?  234  LEU B C    1 
ATOM   9288  O O    . LEU B 1 268 ? 3.918   44.825  56.852 1.00 13.81 ?  234  LEU B O    1 
ATOM   9289  C CB   . LEU B 1 268 ? 3.355   42.155  58.239 1.00 13.45 ?  234  LEU B CB   1 
ATOM   9290  C CG   . LEU B 1 268 ? 1.942   42.704  58.110 1.00 13.69 ?  234  LEU B CG   1 
ATOM   9291  C CD1  . LEU B 1 268 ? 1.345   42.490  56.718 1.00 15.59 ?  234  LEU B CD1  1 
ATOM   9292  C CD2  . LEU B 1 268 ? 1.091   42.074  59.187 1.00 14.21 ?  234  LEU B CD2  1 
ATOM   9293  H H    . LEU B 1 268 ? 5.567   41.200  57.988 1.00 13.00 ?  234  LEU B H    1 
ATOM   9294  H HA   . LEU B 1 268 ? 3.927   42.375  56.281 1.00 15.62 ?  234  LEU B HA   1 
ATOM   9295  H HB2  . LEU B 1 268 ? 3.278   41.188  58.269 1.00 16.14 ?  234  LEU B HB2  1 
ATOM   9296  H HB3  . LEU B 1 268 ? 3.708   42.486  59.079 1.00 16.14 ?  234  LEU B HB3  1 
ATOM   9297  H HG   . LEU B 1 268 ? 1.958   43.667  58.225 1.00 16.43 ?  234  LEU B HG   1 
ATOM   9298  H HD11 . LEU B 1 268 ? 0.410   42.747  56.732 1.00 18.70 ?  234  LEU B HD11 1 
ATOM   9299  H HD12 . LEU B 1 268 ? 1.829   43.036  56.079 1.00 18.70 ?  234  LEU B HD12 1 
ATOM   9300  H HD13 . LEU B 1 268 ? 1.427   41.553  56.480 1.00 18.70 ?  234  LEU B HD13 1 
ATOM   9301  H HD21 . LEU B 1 268 ? 0.158   42.271  59.008 1.00 17.05 ?  234  LEU B HD21 1 
ATOM   9302  H HD22 . LEU B 1 268 ? 1.234   41.115  59.182 1.00 17.05 ?  234  LEU B HD22 1 
ATOM   9303  H HD23 . LEU B 1 268 ? 1.348   42.442  60.047 1.00 17.05 ?  234  LEU B HD23 1 
ATOM   9304  N N    . GLY B 1 269 ? 5.938   44.318  57.683 1.00 13.39 ?  235  GLY B N    1 
ATOM   9305  C CA   . GLY B 1 269 ? 6.347   45.707  57.757 1.00 12.78 ?  235  GLY B CA   1 
ATOM   9306  C C    . GLY B 1 269 ? 6.415   46.421  56.425 1.00 11.78 ?  235  GLY B C    1 
ATOM   9307  O O    . GLY B 1 269 ? 6.383   47.654  56.395 1.00 13.61 ?  235  GLY B O    1 
ATOM   9308  H H    . GLY B 1 269 ? 6.530   43.759  57.957 1.00 16.07 ?  235  GLY B H    1 
ATOM   9309  H HA2  . GLY B 1 269 ? 5.717   46.187  58.318 1.00 15.33 ?  235  GLY B HA2  1 
ATOM   9310  H HA3  . GLY B 1 269 ? 7.227   45.751  58.162 1.00 15.33 ?  235  GLY B HA3  1 
ATOM   9311  N N    . TYR B 1 270 ? 6.460   45.687  55.315 1.00 9.89  ?  236  TYR B N    1 
ATOM   9312  C CA   . TYR B 1 270 ? 6.476   46.339  54.019 1.00 9.63  ?  236  TYR B CA   1 
ATOM   9313  C C    . TYR B 1 270 ? 5.112   46.862  53.588 1.00 10.66 ?  236  TYR B C    1 
ATOM   9314  O O    . TYR B 1 270 ? 5.042   47.658  52.644 1.00 11.36 ?  236  TYR B O    1 
ATOM   9315  C CB   . TYR B 1 270 ? 6.931   45.371  52.911 1.00 12.63 ?  236  TYR B CB   1 
ATOM   9316  C CG   . TYR B 1 270 ? 8.388   44.988  52.987 1.00 14.30 ?  236  TYR B CG   1 
ATOM   9317  C CD1  . TYR B 1 270 ? 9.361   45.875  52.589 1.00 14.06 ?  236  TYR B CD1  1 
ATOM   9318  C CD2  . TYR B 1 270 ? 8.787   43.726  53.401 1.00 18.68 ?  236  TYR B CD2  1 
ATOM   9319  C CE1  . TYR B 1 270 ? 10.710  45.544  52.641 1.00 14.78 ?  236  TYR B CE1  1 
ATOM   9320  C CE2  . TYR B 1 270 ? 10.138  43.379  53.459 1.00 20.55 ?  236  TYR B CE2  1 
ATOM   9321  C CZ   . TYR B 1 270 ? 11.089  44.292  53.064 1.00 18.97 ?  236  TYR B CZ   1 
ATOM   9322  O OH   . TYR B 1 270 ? 12.433  43.952  53.105 1.00 23.39 ?  236  TYR B OH   1 
ATOM   9323  H H    . TYR B 1 270 ? 6.483   44.827  55.291 1.00 11.87 ?  236  TYR B H    1 
ATOM   9324  H HA   . TYR B 1 270 ? 7.106   47.072  54.094 1.00 11.56 ?  236  TYR B HA   1 
ATOM   9325  H HB2  . TYR B 1 270 ? 6.408   44.557  52.975 1.00 15.16 ?  236  TYR B HB2  1 
ATOM   9326  H HB3  . TYR B 1 270 ? 6.782   45.793  52.050 1.00 15.16 ?  236  TYR B HB3  1 
ATOM   9327  H HD1  . TYR B 1 270 ? 9.111   46.715  52.279 1.00 16.87 ?  236  TYR B HD1  1 
ATOM   9328  H HD2  . TYR B 1 270 ? 8.143   43.100  53.645 1.00 22.42 ?  236  TYR B HD2  1 
ATOM   9329  H HE1  . TYR B 1 270 ? 11.353  46.167  52.389 1.00 17.73 ?  236  TYR B HE1  1 
ATOM   9330  H HE2  . TYR B 1 270 ? 10.394  42.538  53.762 1.00 24.66 ?  236  TYR B HE2  1 
ATOM   9331  H HH   . TYR B 1 270 ? 12.892  44.547  52.728 1.00 28.07 ?  236  TYR B HH   1 
ATOM   9332  N N    . PHE B 1 271 ? 4.040   46.427  54.241 1.00 8.98  ?  237  PHE B N    1 
ATOM   9333  C CA   . PHE B 1 271 ? 2.701   46.535  53.688 1.00 8.83  ?  237  PHE B CA   1 
ATOM   9334  C C    . PHE B 1 271 ? 1.746   47.150  54.694 1.00 9.65  ?  237  PHE B C    1 
ATOM   9335  O O    . PHE B 1 271 ? 2.007   47.182  55.892 1.00 10.74 ?  237  PHE B O    1 
ATOM   9336  C CB   . PHE B 1 271 ? 2.185   45.136  53.333 1.00 9.32  ?  237  PHE B CB   1 
ATOM   9337  C CG   . PHE B 1 271 ? 3.136   44.345  52.489 1.00 9.57  ?  237  PHE B CG   1 
ATOM   9338  C CD1  . PHE B 1 271 ? 3.490   44.782  51.235 1.00 9.95  ?  237  PHE B CD1  1 
ATOM   9339  C CD2  . PHE B 1 271 ? 3.708   43.182  52.964 1.00 10.38 ?  237  PHE B CD2  1 
ATOM   9340  C CE1  . PHE B 1 271 ? 4.373   44.059  50.466 1.00 10.82 ?  237  PHE B CE1  1 
ATOM   9341  C CE2  . PHE B 1 271 ? 4.596   42.454  52.182 1.00 10.67 ?  237  PHE B CE2  1 
ATOM   9342  C CZ   . PHE B 1 271 ? 4.916   42.880  50.946 1.00 9.59  ?  237  PHE B CZ   1 
ATOM   9343  H H    . PHE B 1 271 ? 4.066   46.061  55.019 1.00 10.78 ?  237  PHE B H    1 
ATOM   9344  H HA   . PHE B 1 271 ? 2.722   47.112  52.909 1.00 10.60 ?  237  PHE B HA   1 
ATOM   9345  H HB2  . PHE B 1 271 ? 2.033   44.640  54.153 1.00 11.19 ?  237  PHE B HB2  1 
ATOM   9346  H HB3  . PHE B 1 271 ? 1.354   45.224  52.841 1.00 11.19 ?  237  PHE B HB3  1 
ATOM   9347  H HD1  . PHE B 1 271 ? 3.130   45.572  50.904 1.00 11.94 ?  237  PHE B HD1  1 
ATOM   9348  H HD2  . PHE B 1 271 ? 3.496   42.882  53.818 1.00 12.46 ?  237  PHE B HD2  1 
ATOM   9349  H HE1  . PHE B 1 271 ? 4.606   44.365  49.619 1.00 12.98 ?  237  PHE B HE1  1 
ATOM   9350  H HE2  . PHE B 1 271 ? 4.971   41.670  52.514 1.00 12.80 ?  237  PHE B HE2  1 
ATOM   9351  H HZ   . PHE B 1 271 ? 5.499   42.384  50.417 1.00 11.51 ?  237  PHE B HZ   1 
ATOM   9352  N N    . ASN B 1 272 ? 0.611   47.635  54.199 1.00 8.23  ?  238  ASN B N    1 
ATOM   9353  C CA   . ASN B 1 272 ? -0.429  48.126  55.083 1.00 8.16  ?  238  ASN B CA   1 
ATOM   9354  C C    . ASN B 1 272 ? -1.317  47.017  55.619 1.00 8.95  ?  238  ASN B C    1 
ATOM   9355  O O    . ASN B 1 272 ? -2.107  47.262  56.527 1.00 9.05  ?  238  ASN B O    1 
ATOM   9356  C CB   . ASN B 1 272 ? -1.315  49.156  54.379 1.00 8.75  ?  238  ASN B CB   1 
ATOM   9357  C CG   . ASN B 1 272 ? -0.539  50.353  53.898 1.00 9.91  ?  238  ASN B CG   1 
ATOM   9358  O OD1  . ASN B 1 272 ? -0.401  50.598  52.702 1.00 9.20  ?  238  ASN B OD1  1 
ATOM   9359  N ND2  . ASN B 1 272 ? -0.039  51.122  54.845 1.00 11.71 ?  238  ASN B ND2  1 
ATOM   9360  H H    . ASN B 1 272 ? 0.425   47.688  53.361 1.00 9.88  ?  238  ASN B H    1 
ATOM   9361  H HA   . ASN B 1 272 ? 0.007   48.570  55.827 1.00 9.79  ?  238  ASN B HA   1 
ATOM   9362  H HB2  . ASN B 1 272 ? -1.734  48.740  53.610 1.00 10.50 ?  238  ASN B HB2  1 
ATOM   9363  H HB3  . ASN B 1 272 ? -1.993  49.466  54.999 1.00 10.50 ?  238  ASN B HB3  1 
ATOM   9364  H HD21 . ASN B 1 272 ? 0.415   51.822  54.635 1.00 14.05 ?  238  ASN B HD21 1 
ATOM   9365  H HD22 . ASN B 1 272 ? -0.167  50.924  55.672 1.00 14.05 ?  238  ASN B HD22 1 
ATOM   9366  N N    . GLY B 1 273 ? -1.217  45.813  55.071 1.00 9.30  ?  239  GLY B N    1 
ATOM   9367  C CA   . GLY B 1 273 ? -2.022  44.718  55.566 1.00 8.95  ?  239  GLY B CA   1 
ATOM   9368  C C    . GLY B 1 273 ? -1.779  43.467  54.761 1.00 7.44  ?  239  GLY B C    1 
ATOM   9369  O O    . GLY B 1 273 ? -0.983  43.448  53.815 1.00 8.06  ?  239  GLY B O    1 
ATOM   9370  H H    . GLY B 1 273 ? -0.695  45.611  54.418 1.00 11.16 ?  239  GLY B H    1 
ATOM   9371  H HA2  . GLY B 1 273 ? -1.798  44.540  56.493 1.00 10.74 ?  239  GLY B HA2  1 
ATOM   9372  H HA3  . GLY B 1 273 ? -2.962  44.949  55.508 1.00 10.74 ?  239  GLY B HA3  1 
ATOM   9373  N N    . SER B 1 274 ? -2.461  42.411  55.185 1.00 8.06  ?  240  SER B N    1 
ATOM   9374  C CA   . SER B 1 274 ? -2.400  41.131  54.499 1.00 7.38  ?  240  SER B CA   1 
ATOM   9375  C C    . SER B 1 274 ? -3.780  40.635  54.093 1.00 7.91  ?  240  SER B C    1 
ATOM   9376  O O    . SER B 1 274 ? -4.751  40.735  54.846 1.00 8.39  ?  240  SER B O    1 
ATOM   9377  C CB   . SER B 1 274 ? -1.757  40.058  55.385 1.00 8.75  ?  240  SER B CB   1 
ATOM   9378  O OG   . SER B 1 274 ? -1.509  38.841  54.684 1.00 9.24  ?  240  SER B OG   1 
ATOM   9379  H H    . SER B 1 274 ? -2.972  42.414  55.877 1.00 9.68  ?  240  SER B H    1 
ATOM   9380  H HA   . SER B 1 274 ? -1.878  41.263  53.692 1.00 8.85  ?  240  SER B HA   1 
ATOM   9381  H HB2  . SER B 1 274 ? -0.912  40.399  55.718 1.00 10.50 ?  240  SER B HB2  1 
ATOM   9382  H HB3  . SER B 1 274 ? -2.355  39.870  56.125 1.00 10.50 ?  240  SER B HB3  1 
ATOM   9383  H HG   . SER B 1 274 ? -2.059  38.754  54.056 1.00 11.09 ?  240  SER B HG   1 
ATOM   9384  N N    . TYR B 1 275 ? -3.829  40.081  52.887 1.00 8.78  ?  241  TYR B N    1 
ATOM   9385  C CA   . TYR B 1 275 ? -4.877  39.168  52.463 1.00 7.70  ?  241  TYR B CA   1 
ATOM   9386  C C    . TYR B 1 275 ? -4.513  37.774  52.964 1.00 7.79  ?  241  TYR B C    1 
ATOM   9387  O O    . TYR B 1 275 ? -3.330  37.429  53.129 1.00 7.92  ?  241  TYR B O    1 
ATOM   9388  C CB   . TYR B 1 275 ? -4.952  39.249  50.938 1.00 8.61  ?  241  TYR B CB   1 
ATOM   9389  C CG   . TYR B 1 275 ? -5.519  38.080  50.177 1.00 8.03  ?  241  TYR B CG   1 
ATOM   9390  C CD1  . TYR B 1 275 ? -4.756  36.949  49.959 1.00 8.00  ?  241  TYR B CD1  1 
ATOM   9391  C CD2  . TYR B 1 275 ? -6.772  38.147  49.581 1.00 8.05  ?  241  TYR B CD2  1 
ATOM   9392  C CE1  . TYR B 1 275 ? -5.247  35.899  49.202 1.00 7.80  ?  241  TYR B CE1  1 
ATOM   9393  C CE2  . TYR B 1 275 ? -7.260  37.102  48.803 1.00 8.84  ?  241  TYR B CE2  1 
ATOM   9394  C CZ   . TYR B 1 275 ? -6.493  35.976  48.626 1.00 8.74  ?  241  TYR B CZ   1 
ATOM   9395  O OH   . TYR B 1 275 ? -6.988  34.937  47.866 1.00 8.74  ?  241  TYR B OH   1 
ATOM   9396  H H    . TYR B 1 275 ? -3.244  40.225  52.273 1.00 10.54 ?  241  TYR B H    1 
ATOM   9397  H HA   . TYR B 1 275 ? -5.758  39.376  52.813 1.00 9.24  ?  241  TYR B HA   1 
ATOM   9398  H HB2  . TYR B 1 275 ? -5.503  40.015  50.713 1.00 10.33 ?  241  TYR B HB2  1 
ATOM   9399  H HB3  . TYR B 1 275 ? -4.050  39.380  50.608 1.00 10.33 ?  241  TYR B HB3  1 
ATOM   9400  H HD1  . TYR B 1 275 ? -3.903  36.893  50.324 1.00 9.60  ?  241  TYR B HD1  1 
ATOM   9401  H HD2  . TYR B 1 275 ? -7.295  38.906  49.705 1.00 9.66  ?  241  TYR B HD2  1 
ATOM   9402  H HE1  . TYR B 1 275 ? -4.730  35.135  49.082 1.00 9.36  ?  241  TYR B HE1  1 
ATOM   9403  H HE2  . TYR B 1 275 ? -8.099  37.164  48.406 1.00 10.60 ?  241  TYR B HE2  1 
ATOM   9404  H HH   . TYR B 1 275 ? -6.394  34.353  47.755 1.00 10.49 ?  241  TYR B HH   1 
ATOM   9405  N N    . LEU B 1 276 ? -5.537  37.001  53.276 1.00 7.88  ?  242  LEU B N    1 
ATOM   9406  C CA   . LEU B 1 276 ? -5.366  35.632  53.740 1.00 7.67  ?  242  LEU B CA   1 
ATOM   9407  C C    . LEU B 1 276 ? -6.057  34.662  52.802 1.00 8.52  ?  242  LEU B C    1 
ATOM   9408  O O    . LEU B 1 276 ? -7.240  34.837  52.497 1.00 8.41  ?  242  LEU B O    1 
ATOM   9409  C CB   . LEU B 1 276 ? -5.978  35.442  55.127 1.00 8.55  ?  242  LEU B CB   1 
ATOM   9410  C CG   . LEU B 1 276 ? -5.600  36.460  56.187 1.00 8.25  ?  242  LEU B CG   1 
ATOM   9411  C CD1  . LEU B 1 276 ? -6.454  36.271  57.435 1.00 9.21  ?  242  LEU B CD1  1 
ATOM   9412  C CD2  . LEU B 1 276 ? -4.120  36.363  56.534 1.00 11.94 ?  242  LEU B CD2  1 
ATOM   9413  H H    . LEU B 1 276 ? -6.359  37.249  53.227 1.00 9.45  ?  242  LEU B H    1 
ATOM   9414  H HA   . LEU B 1 276 ? -4.415  35.443  53.757 1.00 9.20  ?  242  LEU B HA   1 
ATOM   9415  H HB2  . LEU B 1 276 ? -6.943  35.472  55.035 1.00 10.26 ?  242  LEU B HB2  1 
ATOM   9416  H HB3  . LEU B 1 276 ? -5.704  34.572  55.458 1.00 10.26 ?  242  LEU B HB3  1 
ATOM   9417  H HG   . LEU B 1 276 ? -5.764  37.350  55.836 1.00 9.90  ?  242  LEU B HG   1 
ATOM   9418  H HD11 . LEU B 1 276 ? -6.137  36.871  58.128 1.00 11.06 ?  242  LEU B HD11 1 
ATOM   9419  H HD12 . LEU B 1 276 ? -7.378  36.474  57.220 1.00 11.06 ?  242  LEU B HD12 1 
ATOM   9420  H HD13 . LEU B 1 276 ? -6.378  35.351  57.734 1.00 11.06 ?  242  LEU B HD13 1 
ATOM   9421  H HD21 . LEU B 1 276 ? -3.907  37.036  57.198 1.00 14.33 ?  242  LEU B HD21 1 
ATOM   9422  H HD22 . LEU B 1 276 ? -3.937  35.479  56.888 1.00 14.33 ?  242  LEU B HD22 1 
ATOM   9423  H HD23 . LEU B 1 276 ? -3.597  36.512  55.731 1.00 14.33 ?  242  LEU B HD23 1 
ATOM   9424  N N    . GLU B 1 277 ? -5.330  33.623  52.386 1.00 7.67  ?  243  GLU B N    1 
ATOM   9425  C CA   . GLU B 1 277 ? -5.920  32.458  51.728 1.00 7.38  ?  243  GLU B CA   1 
ATOM   9426  C C    . GLU B 1 277 ? -5.212  31.214  52.253 1.00 8.65  ?  243  GLU B C    1 
ATOM   9427  O O    . GLU B 1 277 ? -4.201  31.288  52.967 1.00 8.51  ?  243  GLU B O    1 
ATOM   9428  C CB   . GLU B 1 277 ? -5.828  32.560  50.199 1.00 7.48  ?  243  GLU B CB   1 
ATOM   9429  C CG   . GLU B 1 277 ? -4.412  32.465  49.673 1.00 7.73  ?  243  GLU B CG   1 
ATOM   9430  C CD   . GLU B 1 277 ? -4.284  32.601  48.166 1.00 7.02  ?  243  GLU B CD   1 
ATOM   9431  O OE1  . GLU B 1 277 ? -5.302  32.926  47.499 1.00 9.13  ?  243  GLU B OE1  1 
ATOM   9432  O OE2  . GLU B 1 277 ? -3.153  32.415  47.647 1.00 8.05  ?  243  GLU B OE2  1 
ATOM   9433  H H    . GLU B 1 277 ? -4.477  33.569  52.475 1.00 9.20  ?  243  GLU B H    1 
ATOM   9434  H HA   . GLU B 1 277 ? -6.862  32.390  51.950 1.00 8.86  ?  243  GLU B HA   1 
ATOM   9435  H HB2  . GLU B 1 277 ? -6.341  31.837  49.805 1.00 8.98  ?  243  GLU B HB2  1 
ATOM   9436  H HB3  . GLU B 1 277 ? -6.192  33.415  49.919 1.00 8.98  ?  243  GLU B HB3  1 
ATOM   9437  H HG2  . GLU B 1 277 ? -3.885  33.173  50.076 1.00 9.27  ?  243  GLU B HG2  1 
ATOM   9438  H HG3  . GLU B 1 277 ? -4.049  31.600  49.920 1.00 9.27  ?  243  GLU B HG3  1 
ATOM   9439  N N    . GLY B 1 278 ? -5.733  30.055  51.864 1.00 8.20  ?  244  GLY B N    1 
ATOM   9440  C CA   . GLY B 1 278 ? -5.247  28.816  52.437 1.00 9.00  ?  244  GLY B CA   1 
ATOM   9441  C C    . GLY B 1 278 ? -5.418  28.756  53.925 1.00 10.03 ?  244  GLY B C    1 
ATOM   9442  O O    . GLY B 1 278 ? -4.718  27.998  54.601 1.00 11.37 ?  244  GLY B O    1 
ATOM   9443  H H    . GLY B 1 278 ? -6.357  29.965  51.279 1.00 9.84  ?  244  GLY B H    1 
ATOM   9444  H HA2  . GLY B 1 278 ? -5.731  28.072  52.045 1.00 10.80 ?  244  GLY B HA2  1 
ATOM   9445  H HA3  . GLY B 1 278 ? -4.303  28.720  52.235 1.00 10.80 ?  244  GLY B HA3  1 
ATOM   9446  N N    . PHE B 1 279 ? -6.338  29.548  54.470 1.00 9.52  ?  245  PHE B N    1 
ATOM   9447  C CA   . PHE B 1 279 ? -6.351  29.787  55.905 1.00 10.39 ?  245  PHE B CA   1 
ATOM   9448  C C    . PHE B 1 279 ? -6.849  28.574  56.679 1.00 9.63  ?  245  PHE B C    1 
ATOM   9449  O O    . PHE B 1 279 ? -6.418  28.347  57.812 1.00 9.78  ?  245  PHE B O    1 
ATOM   9450  C CB   . PHE B 1 279 ? -7.211  31.015  56.206 1.00 8.87  ?  245  PHE B CB   1 
ATOM   9451  C CG   . PHE B 1 279 ? -6.999  31.603  57.580 1.00 8.36  ?  245  PHE B CG   1 
ATOM   9452  C CD1  . PHE B 1 279 ? -5.803  32.233  57.888 1.00 7.80  ?  245  PHE B CD1  1 
ATOM   9453  C CD2  . PHE B 1 279 ? -7.989  31.523  58.558 1.00 9.61  ?  245  PHE B CD2  1 
ATOM   9454  C CE1  . PHE B 1 279 ? -5.590  32.794  59.138 1.00 9.76  ?  245  PHE B CE1  1 
ATOM   9455  C CE2  . PHE B 1 279 ? -7.787  32.080  59.817 1.00 9.96  ?  245  PHE B CE2  1 
ATOM   9456  C CZ   . PHE B 1 279 ? -6.567  32.703  60.112 1.00 9.96  ?  245  PHE B CZ   1 
ATOM   9457  H H    . PHE B 1 279 ? -6.958  29.954  54.034 1.00 11.42 ?  245  PHE B H    1 
ATOM   9458  H HA   . PHE B 1 279 ? -5.447  29.967  56.208 1.00 12.47 ?  245  PHE B HA   1 
ATOM   9459  H HB2  . PHE B 1 279 ? -7.004  31.705  55.557 1.00 10.64 ?  245  PHE B HB2  1 
ATOM   9460  H HB3  . PHE B 1 279 ? -8.146  30.764  56.136 1.00 10.64 ?  245  PHE B HB3  1 
ATOM   9461  H HD1  . PHE B 1 279 ? -5.132  32.280  57.246 1.00 9.36  ?  245  PHE B HD1  1 
ATOM   9462  H HD2  . PHE B 1 279 ? -8.792  31.094  58.368 1.00 11.53 ?  245  PHE B HD2  1 
ATOM   9463  H HE1  . PHE B 1 279 ? -4.791  33.232  59.321 1.00 11.72 ?  245  PHE B HE1  1 
ATOM   9464  H HE2  . PHE B 1 279 ? -8.459  32.039  60.459 1.00 11.95 ?  245  PHE B HE2  1 
ATOM   9465  H HZ   . PHE B 1 279 ? -6.415  33.054  60.960 1.00 11.96 ?  245  PHE B HZ   1 
ATOM   9466  N N    . ASP B 1 280 ? -7.739  27.781  56.081 1.00 9.89  ?  246  ASP B N    1 
ATOM   9467  C CA   . ASP B 1 280 ? -8.289  26.579  56.698 1.00 11.08 ?  246  ASP B CA   1 
ATOM   9468  C C    . ASP B 1 280 ? -7.866  25.330  55.951 1.00 11.87 ?  246  ASP B C    1 
ATOM   9469  O O    . ASP B 1 280 ? -8.503  24.281  56.099 1.00 14.10 ?  246  ASP B O    1 
ATOM   9470  C CB   . ASP B 1 280 ? -9.815  26.683  56.801 1.00 11.31 ?  246  ASP B CB   1 
ATOM   9471  C CG   . ASP B 1 280 ? -10.500 26.820  55.458 1.00 13.37 ?  246  ASP B CG   1 
ATOM   9472  O OD1  . ASP B 1 280 ? -9.844  27.069  54.424 1.00 12.72 ?  246  ASP B OD1  1 
ATOM   9473  O OD2  . ASP B 1 280 ? -11.732 26.642  55.475 1.00 15.90 ?  246  ASP B OD2  1 
ATOM   9474  H H    . ASP B 1 280 ? -8.048  27.925  55.292 1.00 11.87 ?  246  ASP B H    1 
ATOM   9475  H HA   . ASP B 1 280 ? -7.954  26.500  57.605 1.00 13.30 ?  246  ASP B HA   1 
ATOM   9476  H HB2  . ASP B 1 280 ? -10.156 25.882  57.229 1.00 13.57 ?  246  ASP B HB2  1 
ATOM   9477  H HB3  . ASP B 1 280 ? -10.041 27.464  57.331 1.00 13.57 ?  246  ASP B HB3  1 
ATOM   9478  N N    . SER B 1 281 ? -6.803  25.417  55.167 1.00 11.34 ?  247  SER B N    1 
ATOM   9479  C CA   . SER B 1 281 ? -6.310  24.314  54.355 1.00 13.04 ?  247  SER B CA   1 
ATOM   9480  C C    . SER B 1 281 ? -4.968  23.860  54.916 1.00 13.19 ?  247  SER B C    1 
ATOM   9481  O O    . SER B 1 281 ? -3.915  24.359  54.534 1.00 14.19 ?  247  SER B O    1 
ATOM   9482  C CB   . SER B 1 281 ? -6.141  24.768  52.925 1.00 19.53 ?  247  SER B CB   1 
ATOM   9483  O OG   . SER B 1 281 ? -6.015  23.646  52.070 1.00 29.52 ?  247  SER B OG   1 
ATOM   9484  H H    . SER B 1 281 ? -6.332  26.132  55.086 1.00 13.61 ?  247  SER B H    1 
ATOM   9485  H HA   . SER B 1 281 ? -6.938  23.577  54.409 1.00 15.65 ?  247  SER B HA   1 
ATOM   9486  H HB2  . SER B 1 281 ? -6.918  25.285  52.661 1.00 23.44 ?  247  SER B HB2  1 
ATOM   9487  H HB3  . SER B 1 281 ? -5.341  25.312  52.856 1.00 23.44 ?  247  SER B HB3  1 
ATOM   9488  H HG   . SER B 1 281 ? -5.946  23.899  51.272 1.00 35.42 ?  247  SER B HG   1 
ATOM   9489  N N    . GLU B 1 282 ? -5.006  22.859  55.788 1.00 11.65 ?  248  GLU B N    1 
ATOM   9490  C CA   . GLU B 1 282 ? -3.801  22.460  56.491 1.00 13.26 ?  248  GLU B CA   1 
ATOM   9491  C C    . GLU B 1 282 ? -2.817  21.745  55.570 1.00 12.05 ?  248  GLU B C    1 
ATOM   9492  O O    . GLU B 1 282 ? -3.160  21.218  54.509 1.00 14.29 ?  248  GLU B O    1 
ATOM   9493  C CB   . GLU B 1 282 ? -4.148  21.587  57.702 1.00 14.62 ?  248  GLU B CB   1 
ATOM   9494  C CG   . GLU B 1 282 ? -4.603  20.170  57.394 1.00 15.57 ?  248  GLU B CG   1 
ATOM   9495  C CD   . GLU B 1 282 ? -6.083  20.038  57.064 1.00 14.99 ?  248  GLU B CD   1 
ATOM   9496  O OE1  . GLU B 1 282 ? -6.807  21.045  56.890 1.00 14.25 ?  248  GLU B OE1  1 
ATOM   9497  O OE2  . GLU B 1 282 ? -6.548  18.885  56.973 1.00 21.62 ?  248  GLU B OE2  1 
ATOM   9498  H H    . GLU B 1 282 ? -5.708  22.403  55.985 1.00 13.98 ?  248  GLU B H    1 
ATOM   9499  H HA   . GLU B 1 282 ? -3.351  23.255  56.816 1.00 15.91 ?  248  GLU B HA   1 
ATOM   9500  H HB2  . GLU B 1 282 ? -3.360  21.519  58.263 1.00 17.54 ?  248  GLU B HB2  1 
ATOM   9501  H HB3  . GLU B 1 282 ? -4.867  22.018  58.190 1.00 17.54 ?  248  GLU B HB3  1 
ATOM   9502  H HG2  . GLU B 1 282 ? -4.102  19.844  56.630 1.00 18.68 ?  248  GLU B HG2  1 
ATOM   9503  H HG3  . GLU B 1 282 ? -4.425  19.613  58.169 1.00 18.68 ?  248  GLU B HG3  1 
ATOM   9504  N N    . ALA B 1 283 ? -1.568  21.749  56.008 1.00 11.96 ?  249  ALA B N    1 
ATOM   9505  C CA   . ALA B 1 283 ? -0.461  21.139  55.293 1.00 11.54 ?  249  ALA B CA   1 
ATOM   9506  C C    . ALA B 1 283 ? 0.599   20.775  56.327 1.00 10.14 ?  249  ALA B C    1 
ATOM   9507  O O    . ALA B 1 283 ? 0.423   20.985  57.531 1.00 11.90 ?  249  ALA B O    1 
ATOM   9508  C CB   . ALA B 1 283 ? 0.089   22.081  54.216 1.00 14.02 ?  249  ALA B CB   1 
ATOM   9509  H H    . ALA B 1 283 ? -1.326  22.114  56.748 1.00 14.35 ?  249  ALA B H    1 
ATOM   9510  H HA   . ALA B 1 283 ? -0.759  20.330  54.848 1.00 13.85 ?  249  ALA B HA   1 
ATOM   9511  H HB1  . ALA B 1 283 ? 0.816   21.638  53.751 1.00 16.83 ?  249  ALA B HB1  1 
ATOM   9512  H HB2  . ALA B 1 283 ? -0.621  22.297  53.592 1.00 16.83 ?  249  ALA B HB2  1 
ATOM   9513  H HB3  . ALA B 1 283 ? 0.413   22.891  54.641 1.00 16.83 ?  249  ALA B HB3  1 
ATOM   9514  N N    . PHE B 1 284 ? 1.713   20.232  55.843 1.00 12.64 ?  250  PHE B N    1 
ATOM   9515  C CA   . PHE B 1 284 ? 2.909   19.995  56.651 1.00 12.60 ?  250  PHE B CA   1 
ATOM   9516  C C    . PHE B 1 284 ? 2.689   18.950  57.735 1.00 12.84 ?  250  PHE B C    1 
ATOM   9517  O O    . PHE B 1 284 ? 3.428   18.933  58.724 1.00 15.66 ?  250  PHE B O    1 
ATOM   9518  C CB   . PHE B 1 284 ? 3.430   21.298  57.286 1.00 13.28 ?  250  PHE B CB   1 
ATOM   9519  C CG   . PHE B 1 284 ? 3.271   22.501  56.404 1.00 11.58 ?  250  PHE B CG   1 
ATOM   9520  C CD1  . PHE B 1 284 ? 3.923   22.573  55.191 1.00 12.27 ?  250  PHE B CD1  1 
ATOM   9521  C CD2  . PHE B 1 284 ? 2.426   23.535  56.777 1.00 12.84 ?  250  PHE B CD2  1 
ATOM   9522  C CE1  . PHE B 1 284 ? 3.742   23.672  54.361 1.00 12.73 ?  250  PHE B CE1  1 
ATOM   9523  C CE2  . PHE B 1 284 ? 2.258   24.629  55.962 1.00 13.19 ?  250  PHE B CE2  1 
ATOM   9524  C CZ   . PHE B 1 284 ? 2.902   24.687  54.756 1.00 11.51 ?  250  PHE B CZ   1 
ATOM   9525  H H    . PHE B 1 284 ? 1.803   19.984  55.025 1.00 15.16 ?  250  PHE B H    1 
ATOM   9526  H HA   . PHE B 1 284 ? 3.597   19.655  56.058 1.00 15.12 ?  250  PHE B HA   1 
ATOM   9527  H HB2  . PHE B 1 284 ? 2.939   21.464  58.106 1.00 15.93 ?  250  PHE B HB2  1 
ATOM   9528  H HB3  . PHE B 1 284 ? 4.375   21.195  57.481 1.00 15.93 ?  250  PHE B HB3  1 
ATOM   9529  H HD1  . PHE B 1 284 ? 4.487   21.882  54.928 1.00 14.73 ?  250  PHE B HD1  1 
ATOM   9530  H HD2  . PHE B 1 284 ? 1.969   23.487  57.586 1.00 15.41 ?  250  PHE B HD2  1 
ATOM   9531  H HE1  . PHE B 1 284 ? 4.185   23.722  53.545 1.00 15.28 ?  250  PHE B HE1  1 
ATOM   9532  H HE2  . PHE B 1 284 ? 1.706   25.329  56.229 1.00 15.83 ?  250  PHE B HE2  1 
ATOM   9533  H HZ   . PHE B 1 284 ? 2.771   25.420  54.199 1.00 13.82 ?  250  PHE B HZ   1 
ATOM   9534  N N    . GLY B 1 285 ? 1.660   18.115  57.598 1.00 11.90 ?  251  GLY B N    1 
ATOM   9535  C CA   . GLY B 1 285 ? 1.342   17.140  58.624 1.00 13.58 ?  251  GLY B CA   1 
ATOM   9536  C C    . GLY B 1 285 ? 0.602   17.694  59.821 1.00 15.77 ?  251  GLY B C    1 
ATOM   9537  O O    . GLY B 1 285 ? 0.362   16.964  60.787 1.00 15.84 ?  251  GLY B O    1 
ATOM   9538  H H    . GLY B 1 285 ? 1.134   18.098  56.917 1.00 14.28 ?  251  GLY B H    1 
ATOM   9539  H HA2  . GLY B 1 285 ? 0.792   16.444  58.232 1.00 16.30 ?  251  GLY B HA2  1 
ATOM   9540  H HA3  . GLY B 1 285 ? 2.169   16.746  58.945 1.00 16.30 ?  251  GLY B HA3  1 
ATOM   9541  N N    . MET B 1 286 ? 0.194   18.957  59.783 1.00 11.25 ?  252  MET B N    1 
ATOM   9542  C CA   . MET B 1 286 ? -0.489  19.580  60.901 1.00 13.71 ?  252  MET B CA   1 
ATOM   9543  C C    . MET B 1 286 ? -1.961  19.207  60.863 1.00 12.49 ?  252  MET B C    1 
ATOM   9544  O O    . MET B 1 286 ? -2.544  19.025  59.794 1.00 13.18 ?  252  MET B O    1 
ATOM   9545  C CB   . MET B 1 286 ? -0.386  21.096  60.705 1.00 12.16 ?  252  MET B CB   1 
ATOM   9546  C CG   . MET B 1 286 ? 1.002   21.634  60.886 1.00 11.67 ?  252  MET B CG   1 
ATOM   9547  S SD   . MET B 1 286 ? 1.105   23.429  60.723 1.00 12.84 ?  252  MET B SD   1 
ATOM   9548  C CE   . MET B 1 286 ? 0.542   23.916  62.367 1.00 14.05 ?  252  MET B CE   1 
ATOM   9549  H H    . MET B 1 286 ? 0.304   19.481  59.109 1.00 13.50 ?  252  MET B H    1 
ATOM   9550  H HA   . MET B 1 286 ? -0.099  19.309  61.747 1.00 16.46 ?  252  MET B HA   1 
ATOM   9551  H HB2  . MET B 1 286 ? -0.674  21.314  59.804 1.00 14.59 ?  252  MET B HB2  1 
ATOM   9552  H HB3  . MET B 1 286 ? -0.961  21.534  61.352 1.00 14.59 ?  252  MET B HB3  1 
ATOM   9553  H HG2  . MET B 1 286 ? 1.316   21.398  61.773 1.00 14.00 ?  252  MET B HG2  1 
ATOM   9554  H HG3  . MET B 1 286 ? 1.580   21.241  60.214 1.00 14.00 ?  252  MET B HG3  1 
ATOM   9555  H HE1  . MET B 1 286 ? 0.540   24.884  62.426 1.00 16.86 ?  252  MET B HE1  1 
ATOM   9556  H HE2  . MET B 1 286 ? -0.355  23.575  62.507 1.00 16.86 ?  252  MET B HE2  1 
ATOM   9557  H HE3  . MET B 1 286 ? 1.145   23.545  63.030 1.00 16.86 ?  252  MET B HE3  1 
ATOM   9558  N N    . SER B 1 287 ? -2.569  19.144  62.041 1.00 13.12 ?  253  SER B N    1 
ATOM   9559  C CA   . SER B 1 287 ? -4.011  19.010  62.098 1.00 14.08 ?  253  SER B CA   1 
ATOM   9560  C C    . SER B 1 287 ? -4.675  20.288  61.588 1.00 13.87 ?  253  SER B C    1 
ATOM   9561  O O    . SER B 1 287 ? -4.120  21.387  61.660 1.00 12.88 ?  253  SER B O    1 
ATOM   9562  C CB   . SER B 1 287 ? -4.493  18.722  63.524 1.00 12.74 ?  253  SER B CB   1 
ATOM   9563  O OG   . SER B 1 287 ? -4.286  19.812  64.392 1.00 14.98 ?  253  SER B OG   1 
ATOM   9564  H H    . SER B 1 287 ? -2.174  19.176  62.804 1.00 15.74 ?  253  SER B H    1 
ATOM   9565  H HA   . SER B 1 287 ? -4.278  18.262  61.542 1.00 16.90 ?  253  SER B HA   1 
ATOM   9566  H HB2  . SER B 1 287 ? -5.443  18.526  63.495 1.00 15.29 ?  253  SER B HB2  1 
ATOM   9567  H HB3  . SER B 1 287 ? -4.006  17.957  63.866 1.00 15.29 ?  253  SER B HB3  1 
ATOM   9568  H HG   . SER B 1 287 ? -4.526  19.608  65.171 1.00 17.98 ?  253  SER B HG   1 
ATOM   9569  N N    . ASN B 1 288 ? -5.891  20.138  61.076 1.00 12.59 ?  254  ASN B N    1 
ATOM   9570  C CA   . ASN B 1 288 ? -6.648  21.311  60.657 1.00 12.01 ?  254  ASN B CA   1 
ATOM   9571  C C    . ASN B 1 288 ? -6.798  22.294  61.810 1.00 11.84 ?  254  ASN B C    1 
ATOM   9572  O O    . ASN B 1 288 ? -6.616  23.509  61.640 1.00 11.54 ?  254  ASN B O    1 
ATOM   9573  C CB   . ASN B 1 288 ? -8.024  20.880  60.141 1.00 11.98 ?  254  ASN B CB   1 
ATOM   9574  C CG   . ASN B 1 288 ? -8.886  22.053  59.727 1.00 14.59 ?  254  ASN B CG   1 
ATOM   9575  O OD1  . ASN B 1 288 ? -9.779  22.471  60.463 1.00 15.31 ?  254  ASN B OD1  1 
ATOM   9576  N ND2  . ASN B 1 288 ? -8.636  22.566  58.531 1.00 16.29 ?  254  ASN B ND2  1 
ATOM   9577  H H    . ASN B 1 288 ? -6.292  19.385  60.963 1.00 15.11 ?  254  ASN B H    1 
ATOM   9578  H HA   . ASN B 1 288 ? -6.179  21.756  59.934 1.00 14.41 ?  254  ASN B HA   1 
ATOM   9579  H HB2  . ASN B 1 288 ? -7.907  20.306  59.368 1.00 14.38 ?  254  ASN B HB2  1 
ATOM   9580  H HB3  . ASN B 1 288 ? -8.489  20.399  60.844 1.00 14.38 ?  254  ASN B HB3  1 
ATOM   9581  H HD21 . ASN B 1 288 ? -9.096  23.234  58.245 1.00 19.55 ?  254  ASN B HD21 1 
ATOM   9582  H HD22 . ASN B 1 288 ? -8.014  22.231  58.041 1.00 19.55 ?  254  ASN B HD22 1 
ATOM   9583  N N    . ALA B 1 289 ? -7.108  21.797  63.013 1.00 11.26 ?  255  ALA B N    1 
ATOM   9584  C CA   . ALA B 1 289 ? -7.336  22.688  64.136 1.00 11.24 ?  255  ALA B CA   1 
ATOM   9585  C C    . ALA B 1 289 ? -6.060  23.431  64.532 1.00 11.65 ?  255  ALA B C    1 
ATOM   9586  O O    . ALA B 1 289 ? -6.102  24.626  64.813 1.00 11.65 ?  255  ALA B O    1 
ATOM   9587  C CB   . ALA B 1 289 ? -7.919  21.931  65.330 1.00 13.80 ?  255  ALA B CB   1 
ATOM   9588  H H    . ALA B 1 289 ? -7.190  20.960  63.196 1.00 13.52 ?  255  ALA B H    1 
ATOM   9589  H HA   . ALA B 1 289 ? -7.993  23.348  63.865 1.00 13.49 ?  255  ALA B HA   1 
ATOM   9590  H HB1  . ALA B 1 289 ? -8.083  22.558  66.052 1.00 16.55 ?  255  ALA B HB1  1 
ATOM   9591  H HB2  . ALA B 1 289 ? -8.752  21.512  65.062 1.00 16.55 ?  255  ALA B HB2  1 
ATOM   9592  H HB3  . ALA B 1 289 ? -7.285  21.255  65.616 1.00 16.55 ?  255  ALA B HB3  1 
ATOM   9593  N N    . GLU B 1 290 ? -4.917  22.727  64.624 1.00 11.48 ?  256  GLU B N    1 
ATOM   9594  C CA   . GLU B 1 290 ? -3.695  23.424  65.032 1.00 12.82 ?  256  GLU B CA   1 
ATOM   9595  C C    . GLU B 1 290 ? -3.200  24.390  63.966 1.00 10.71 ?  256  GLU B C    1 
ATOM   9596  O O    . GLU B 1 290 ? -2.648  25.448  64.299 1.00 11.84 ?  256  GLU B O    1 
ATOM   9597  C CB   . GLU B 1 290 ? -2.587  22.458  65.449 1.00 13.09 ?  256  GLU B CB   1 
ATOM   9598  C CG   . GLU B 1 290 ? -2.894  21.709  66.739 1.00 14.65 ?  256  GLU B CG   1 
ATOM   9599  C CD   . GLU B 1 290 ? -2.075  20.464  66.915 1.00 16.03 ?  256  GLU B CD   1 
ATOM   9600  O OE1  . GLU B 1 290 ? -1.153  20.501  67.766 1.00 16.80 ?  256  GLU B OE1  1 
ATOM   9601  O OE2  . GLU B 1 290 ? -2.333  19.450  66.233 1.00 17.07 ?  256  GLU B OE2  1 
ATOM   9602  H H    . GLU B 1 290 ? -4.832  21.887  64.463 1.00 13.78 ?  256  GLU B H    1 
ATOM   9603  H HA   . GLU B 1 290 ? -3.915  23.940  65.824 1.00 15.39 ?  256  GLU B HA   1 
ATOM   9604  H HB2  . GLU B 1 290 ? -2.462  21.802  64.746 1.00 15.71 ?  256  GLU B HB2  1 
ATOM   9605  H HB3  . GLU B 1 290 ? -1.768  22.960  65.584 1.00 15.71 ?  256  GLU B HB3  1 
ATOM   9606  H HG2  . GLU B 1 290 ? -2.713  22.293  67.492 1.00 17.58 ?  256  GLU B HG2  1 
ATOM   9607  H HG3  . GLU B 1 290 ? -3.829  21.452  66.737 1.00 17.58 ?  256  GLU B HG3  1 
ATOM   9608  N N    . TYR B 1 291 ? -3.394  24.039  62.697 1.00 9.98  ?  257  TYR B N    1 
ATOM   9609  C CA   . TYR B 1 291 ? -3.076  24.949  61.600 1.00 10.03 ?  257  TYR B CA   1 
ATOM   9610  C C    . TYR B 1 291 ? -3.900  26.227  61.704 1.00 10.86 ?  257  TYR B C    1 
ATOM   9611  O O    . TYR B 1 291 ? -3.366  27.331  61.563 1.00 10.83 ?  257  TYR B O    1 
ATOM   9612  C CB   . TYR B 1 291 ? -3.334  24.220  60.289 1.00 10.17 ?  257  TYR B CB   1 
ATOM   9613  C CG   . TYR B 1 291 ? -3.046  24.980  59.021 1.00 10.51 ?  257  TYR B CG   1 
ATOM   9614  C CD1  . TYR B 1 291 ? -4.032  25.768  58.432 1.00 10.15 ?  257  TYR B CD1  1 
ATOM   9615  C CD2  . TYR B 1 291 ? -1.830  24.860  58.364 1.00 10.76 ?  257  TYR B CD2  1 
ATOM   9616  C CE1  . TYR B 1 291 ? -3.794  26.429  57.256 1.00 12.11 ?  257  TYR B CE1  1 
ATOM   9617  C CE2  . TYR B 1 291 ? -1.583  25.523  57.178 1.00 11.97 ?  257  TYR B CE2  1 
ATOM   9618  C CZ   . TYR B 1 291 ? -2.575  26.306  56.631 1.00 11.71 ?  257  TYR B CZ   1 
ATOM   9619  O OH   . TYR B 1 291 ? -2.316  26.952  55.444 1.00 13.58 ?  257  TYR B OH   1 
ATOM   9620  H H    . TYR B 1 291 ? -3.708  23.279  62.443 1.00 11.98 ?  257  TYR B H    1 
ATOM   9621  H HA   . TYR B 1 291 ? -2.142  25.209  61.628 1.00 12.03 ?  257  TYR B HA   1 
ATOM   9622  H HB2  . TYR B 1 291 ? -2.779  23.424  60.274 1.00 12.20 ?  257  TYR B HB2  1 
ATOM   9623  H HB3  . TYR B 1 291 ? -4.271  23.971  60.263 1.00 12.20 ?  257  TYR B HB3  1 
ATOM   9624  H HD1  . TYR B 1 291 ? -4.863  25.847  58.842 1.00 12.18 ?  257  TYR B HD1  1 
ATOM   9625  H HD2  . TYR B 1 291 ? -1.166  24.322  58.730 1.00 12.91 ?  257  TYR B HD2  1 
ATOM   9626  H HE1  . TYR B 1 291 ? -4.457  26.961  56.880 1.00 14.53 ?  257  TYR B HE1  1 
ATOM   9627  H HE2  . TYR B 1 291 ? -0.759  25.442  56.755 1.00 14.36 ?  257  TYR B HE2  1 
ATOM   9628  H HH   . TYR B 1 291 ? -3.025  27.034  55.001 1.00 16.30 ?  257  TYR B HH   1 
ATOM   9629  N N    . LEU B 1 292 ? -5.194  26.101  61.997 1.00 9.54  ?  258  LEU B N    1 
ATOM   9630  C CA   . LEU B 1 292 ? -6.022  27.281  62.193 1.00 9.06  ?  258  LEU B CA   1 
ATOM   9631  C C    . LEU B 1 292 ? -5.608  28.061  63.435 1.00 10.58 ?  258  LEU B C    1 
ATOM   9632  O O    . LEU B 1 292 ? -5.587  29.291  63.413 1.00 10.13 ?  258  LEU B O    1 
ATOM   9633  C CB   . LEU B 1 292 ? -7.504  26.894  62.235 1.00 10.45 ?  258  LEU B CB   1 
ATOM   9634  C CG   . LEU B 1 292 ? -8.145  26.906  60.839 1.00 10.36 ?  258  LEU B CG   1 
ATOM   9635  C CD1  . LEU B 1 292 ? -9.413  26.083  60.808 1.00 11.81 ?  258  LEU B CD1  1 
ATOM   9636  C CD2  . LEU B 1 292 ? -8.433  28.324  60.388 1.00 11.34 ?  258  LEU B CD2  1 
ATOM   9637  H H    . LEU B 1 292 ? -5.608  25.353  62.086 1.00 11.45 ?  258  LEU B H    1 
ATOM   9638  H HA   . LEU B 1 292 ? -5.904  27.872  61.433 1.00 10.87 ?  258  LEU B HA   1 
ATOM   9639  H HB2  . LEU B 1 292 ? -7.589  25.999  62.600 1.00 12.54 ?  258  LEU B HB2  1 
ATOM   9640  H HB3  . LEU B 1 292 ? -7.982  27.527  62.794 1.00 12.54 ?  258  LEU B HB3  1 
ATOM   9641  H HG   . LEU B 1 292 ? -7.515  26.509  60.216 1.00 12.43 ?  258  LEU B HG   1 
ATOM   9642  H HD11 . LEU B 1 292 ? -9.739  26.038  59.896 1.00 14.17 ?  258  LEU B HD11 1 
ATOM   9643  H HD12 . LEU B 1 292 ? -9.218  25.190  61.134 1.00 14.17 ?  258  LEU B HD12 1 
ATOM   9644  H HD13 . LEU B 1 292 ? -10.076 26.505  61.376 1.00 14.17 ?  258  LEU B HD13 1 
ATOM   9645  H HD21 . LEU B 1 292 ? -8.834  28.300  59.505 1.00 13.60 ?  258  LEU B HD21 1 
ATOM   9646  H HD22 . LEU B 1 292 ? -9.044  28.737  61.018 1.00 13.60 ?  258  LEU B HD22 1 
ATOM   9647  H HD23 . LEU B 1 292 ? -7.601  28.822  60.360 1.00 13.60 ?  258  LEU B HD23 1 
ATOM   9648  N N    . VAL B 1 293 ? -5.251  27.374  64.530 1.00 9.65  ?  259  VAL B N    1 
ATOM   9649  C CA   . VAL B 1 293 ? -4.795  28.085  65.721 1.00 11.14 ?  259  VAL B CA   1 
ATOM   9650  C C    . VAL B 1 293 ? -3.631  29.016  65.379 1.00 10.05 ?  259  VAL B C    1 
ATOM   9651  O O    . VAL B 1 293 ? -3.587  30.174  65.808 1.00 10.00 ?  259  VAL B O    1 
ATOM   9652  C CB   . VAL B 1 293 ? -4.410  27.087  66.833 1.00 11.79 ?  259  VAL B CB   1 
ATOM   9653  C CG1  . VAL B 1 293 ? -3.608  27.761  67.943 1.00 13.42 ?  259  VAL B CG1  1 
ATOM   9654  C CG2  . VAL B 1 293 ? -5.657  26.413  67.387 1.00 15.02 ?  259  VAL B CG2  1 
ATOM   9655  H H    . VAL B 1 293 ? -5.265  26.517  64.602 1.00 11.58 ?  259  VAL B H    1 
ATOM   9656  H HA   . VAL B 1 293 ? -5.528  28.629  66.048 1.00 13.37 ?  259  VAL B HA   1 
ATOM   9657  H HB   . VAL B 1 293 ? -3.838  26.404  66.450 1.00 14.15 ?  259  VAL B HB   1 
ATOM   9658  H HG11 . VAL B 1 293 ? -3.594  27.181  68.720 1.00 16.11 ?  259  VAL B HG11 1 
ATOM   9659  H HG12 . VAL B 1 293 ? -2.703  27.916  67.629 1.00 16.11 ?  259  VAL B HG12 1 
ATOM   9660  H HG13 . VAL B 1 293 ? -4.029  28.606  68.168 1.00 16.11 ?  259  VAL B HG13 1 
ATOM   9661  H HG21 . VAL B 1 293 ? -5.392  25.739  68.032 1.00 18.02 ?  259  VAL B HG21 1 
ATOM   9662  H HG22 . VAL B 1 293 ? -6.213  27.082  67.817 1.00 18.02 ?  259  VAL B HG22 1 
ATOM   9663  H HG23 . VAL B 1 293 ? -6.143  25.999  66.657 1.00 18.02 ?  259  VAL B HG23 1 
ATOM   9664  N N    . GLU B 1 294 ? -2.671  28.516  64.593 1.00 9.88  ?  260  GLU B N    1 
ATOM   9665  C CA   . GLU B 1 294 ? -1.496  29.322  64.283 1.00 11.14 ?  260  GLU B CA   1 
ATOM   9666  C C    . GLU B 1 294 ? -1.864  30.483  63.367 1.00 9.30  ?  260  GLU B C    1 
ATOM   9667  O O    . GLU B 1 294 ? -1.365  31.598  63.539 1.00 9.58  ?  260  GLU B O    1 
ATOM   9668  C CB   . GLU B 1 294 ? -0.406  28.447  63.676 1.00 12.96 ?  260  GLU B CB   1 
ATOM   9669  C CG   . GLU B 1 294 ? 0.177   27.446  64.667 1.00 10.81 ?  260  GLU B CG   1 
ATOM   9670  C CD   . GLU B 1 294 ? 1.590   26.979  64.338 1.00 17.85 ?  260  GLU B CD   1 
ATOM   9671  O OE1  . GLU B 1 294 ? 2.269   27.595  63.505 1.00 18.02 ?  260  GLU B OE1  1 
ATOM   9672  O OE2  . GLU B 1 294 ? 1.994   25.947  64.904 1.00 16.52 ?  260  GLU B OE2  1 
ATOM   9673  H H    . GLU B 1 294 ? -2.678  27.733  64.238 1.00 11.86 ?  260  GLU B H    1 
ATOM   9674  H HA   . GLU B 1 294 ? -1.136  29.698  65.102 1.00 13.37 ?  260  GLU B HA   1 
ATOM   9675  H HB2  . GLU B 1 294 ? -0.780  27.948  62.933 1.00 15.55 ?  260  GLU B HB2  1 
ATOM   9676  H HB3  . GLU B 1 294 ? 0.317   29.014  63.365 1.00 15.55 ?  260  GLU B HB3  1 
ATOM   9677  H HG2  . GLU B 1 294 ? 0.203   27.859  65.545 1.00 12.97 ?  260  GLU B HG2  1 
ATOM   9678  H HG3  . GLU B 1 294 ? -0.393  26.662  64.686 1.00 12.97 ?  260  GLU B HG3  1 
ATOM   9679  N N    . GLY B 1 295 ? -2.735  30.251  62.387 1.00 9.57  ?  261  GLY B N    1 
ATOM   9680  C CA   . GLY B 1 295 ? -3.173  31.338  61.524 1.00 10.14 ?  261  GLY B CA   1 
ATOM   9681  C C    . GLY B 1 295 ? -3.969  32.385  62.273 1.00 10.00 ?  261  GLY B C    1 
ATOM   9682  O O    . GLY B 1 295 ? -3.805  33.590  62.044 1.00 9.15  ?  261  GLY B O    1 
ATOM   9683  H H    . GLY B 1 295 ? -3.081  29.485  62.205 1.00 11.48 ?  261  GLY B H    1 
ATOM   9684  H HA2  . GLY B 1 295 ? -2.398  31.767  61.130 1.00 12.17 ?  261  GLY B HA2  1 
ATOM   9685  H HA3  . GLY B 1 295 ? -3.730  30.980  60.815 1.00 12.17 ?  261  GLY B HA3  1 
ATOM   9686  N N    . ILE B 1 296 ? -4.834  31.944  63.189 1.00 8.82  ?  262  ILE B N    1 
ATOM   9687  C CA   . ILE B 1 296 ? -5.593  32.866  64.033 1.00 9.24  ?  262  ILE B CA   1 
ATOM   9688  C C    . ILE B 1 296 ? -4.648  33.735  64.860 1.00 9.02  ?  262  ILE B C    1 
ATOM   9689  O O    . ILE B 1 296 ? -4.840  34.947  64.983 1.00 9.84  ?  262  ILE B O    1 
ATOM   9690  C CB   . ILE B 1 296 ? -6.593  32.076  64.907 1.00 9.14  ?  262  ILE B CB   1 
ATOM   9691  C CG1  . ILE B 1 296 ? -7.734  31.533  64.040 1.00 9.70  ?  262  ILE B CG1  1 
ATOM   9692  C CG2  . ILE B 1 296 ? -7.095  32.913  66.076 1.00 10.69 ?  262  ILE B CG2  1 
ATOM   9693  C CD1  . ILE B 1 296 ? -8.565  30.449  64.695 1.00 11.93 ?  262  ILE B CD1  1 
ATOM   9694  H H    . ILE B 1 296 ? -5.000  31.114  63.342 1.00 10.58 ?  262  ILE B H    1 
ATOM   9695  H HA   . ILE B 1 296 ? -6.106  33.467  63.469 1.00 11.09 ?  262  ILE B HA   1 
ATOM   9696  H HB   . ILE B 1 296 ? -6.131  31.317  65.295 1.00 10.97 ?  262  ILE B HB   1 
ATOM   9697  H HG12 . ILE B 1 296 ? -8.331  32.266  63.821 1.00 11.64 ?  262  ILE B HG12 1 
ATOM   9698  H HG13 . ILE B 1 296 ? -7.355  31.160  63.229 1.00 11.64 ?  262  ILE B HG13 1 
ATOM   9699  H HG21 . ILE B 1 296 ? -7.752  32.400  66.572 1.00 12.83 ?  262  ILE B HG21 1 
ATOM   9700  H HG22 . ILE B 1 296 ? -6.346  33.134  66.651 1.00 12.83 ?  262  ILE B HG22 1 
ATOM   9701  H HG23 . ILE B 1 296 ? -7.500  33.724  65.733 1.00 12.83 ?  262  ILE B HG23 1 
ATOM   9702  H HD11 . ILE B 1 296 ? -9.164  30.067  64.035 1.00 14.31 ?  262  ILE B HD11 1 
ATOM   9703  H HD12 . ILE B 1 296 ? -7.973  29.763  65.041 1.00 14.31 ?  262  ILE B HD12 1 
ATOM   9704  H HD13 . ILE B 1 296 ? -9.078  30.839  65.421 1.00 14.31 ?  262  ILE B HD13 1 
ATOM   9705  N N    . GLU B 1 297 ? -3.624  33.121  65.460 1.00 10.58 ?  263  GLU B N    1 
ATOM   9706  C CA   . GLU B 1 297 ? -2.673  33.877  66.275 1.00 10.93 ?  263  GLU B CA   1 
ATOM   9707  C C    . GLU B 1 297 ? -1.949  34.938  65.444 1.00 9.39  ?  263  GLU B C    1 
ATOM   9708  O O    . GLU B 1 297 ? -1.826  36.097  65.855 1.00 10.83 ?  263  GLU B O    1 
ATOM   9709  C CB   . GLU B 1 297 ? -1.688  32.912  66.955 1.00 13.12 ?  263  GLU B CB   1 
ATOM   9710  C CG   . GLU B 1 297 ? -2.108  32.431  68.369 1.00 28.12 ?  263  GLU B CG   1 
ATOM   9711  C CD   . GLU B 1 297 ? -1.582  31.037  68.786 1.00 32.44 ?  263  GLU B CD   1 
ATOM   9712  O OE1  . GLU B 1 297 ? -2.195  30.459  69.740 1.00 23.53 ?  263  GLU B OE1  1 
ATOM   9713  O OE2  . GLU B 1 297 ? -0.607  30.513  68.164 1.00 23.22 ?  263  GLU B OE2  1 
ATOM   9714  H H    . GLU B 1 297 ? -3.459  32.278  65.412 1.00 12.69 ?  263  GLU B H    1 
ATOM   9715  H HA   . GLU B 1 297 ? -3.152  34.345  66.977 1.00 13.12 ?  263  GLU B HA   1 
ATOM   9716  H HB2  . GLU B 1 297 ? -1.595  32.125  66.396 1.00 15.75 ?  263  GLU B HB2  1 
ATOM   9717  H HB3  . GLU B 1 297 ? -0.832  33.360  67.043 1.00 15.75 ?  263  GLU B HB3  1 
ATOM   9718  H HG2  . GLU B 1 297 ? -1.776  33.070  69.020 1.00 33.75 ?  263  GLU B HG2  1 
ATOM   9719  H HG3  . GLU B 1 297 ? -3.076  32.395  68.404 1.00 33.75 ?  263  GLU B HG3  1 
ATOM   9720  N N    . ALA B 1 298 ? -1.519  34.579  64.236 1.00 9.54  ?  264  ALA B N    1 
ATOM   9721  C CA   . ALA B 1 298 ? -0.845  35.548  63.382 1.00 9.58  ?  264  ALA B CA   1 
ATOM   9722  C C    . ALA B 1 298 ? -1.788  36.680  63.008 1.00 10.13 ?  264  ALA B C    1 
ATOM   9723  O O    . ALA B 1 298 ? -1.396  37.856  63.008 1.00 10.15 ?  264  ALA B O    1 
ATOM   9724  C CB   . ALA B 1 298 ? -0.321  34.858  62.126 1.00 10.59 ?  264  ALA B CB   1 
ATOM   9725  H H    . ALA B 1 298 ? -1.604  33.795  63.894 1.00 11.44 ?  264  ALA B H    1 
ATOM   9726  H HA   . ALA B 1 298 ? -0.087  35.922  63.860 1.00 11.50 ?  264  ALA B HA   1 
ATOM   9727  H HB1  . ALA B 1 298 ? 0.192   35.496  61.605 1.00 12.71 ?  264  ALA B HB1  1 
ATOM   9728  H HB2  . ALA B 1 298 ? 0.243   34.113  62.386 1.00 12.71 ?  264  ALA B HB2  1 
ATOM   9729  H HB3  . ALA B 1 298 ? -1.074  34.536  61.606 1.00 12.71 ?  264  ALA B HB3  1 
ATOM   9730  N N    . THR B 1 299 ? -3.029  36.341  62.658 1.00 9.02  ?  265  THR B N    1 
ATOM   9731  C CA   . THR B 1 299 ? -3.989  37.337  62.196 1.00 10.75 ?  265  THR B CA   1 
ATOM   9732  C C    . THR B 1 299 ? -4.380  38.276  63.323 1.00 10.12 ?  265  THR B C    1 
ATOM   9733  O O    . THR B 1 299 ? -4.445  39.496  63.137 1.00 10.55 ?  265  THR B O    1 
ATOM   9734  C CB   . THR B 1 299 ? -5.212  36.634  61.591 1.00 9.18  ?  265  THR B CB   1 
ATOM   9735  O OG1  . THR B 1 299 ? -4.790  35.785  60.511 1.00 9.57  ?  265  THR B OG1  1 
ATOM   9736  C CG2  . THR B 1 299 ? -6.193  37.635  61.053 1.00 9.43  ?  265  THR B CG2  1 
ATOM   9737  H H    . THR B 1 299 ? -3.339  35.539  62.680 1.00 10.82 ?  265  THR B H    1 
ATOM   9738  H HA   . THR B 1 299 ? -3.589  37.876  61.496 1.00 12.90 ?  265  THR B HA   1 
ATOM   9739  H HB   . THR B 1 299 ? -5.648  36.110  62.280 1.00 11.02 ?  265  THR B HB   1 
ATOM   9740  H HG1  . THR B 1 299 ? -4.425  35.093  60.816 1.00 11.48 ?  265  THR B HG1  1 
ATOM   9741  H HG21 . THR B 1 299 ? -6.984  37.180  60.724 1.00 11.32 ?  265  THR B HG21 1 
ATOM   9742  H HG22 . THR B 1 299 ? -6.453  38.254  61.753 1.00 11.32 ?  265  THR B HG22 1 
ATOM   9743  H HG23 . THR B 1 299 ? -5.791  38.134  60.325 1.00 11.32 ?  265  THR B HG23 1 
ATOM   9744  N N    . GLN B 1 300 ? -4.597  37.735  64.522 1.00 9.63  ?  266  GLN B N    1 
ATOM   9745  C CA   . GLN B 1 300 ? -4.908  38.574  65.676 1.00 9.44  ?  266  GLN B CA   1 
ATOM   9746  C C    . GLN B 1 300 ? -3.796  39.583  65.927 1.00 11.25 ?  266  GLN B C    1 
ATOM   9747  O O    . GLN B 1 300 ? -4.057  40.767  66.177 1.00 10.90 ?  266  GLN B O    1 
ATOM   9748  C CB   . GLN B 1 300 ? -5.100  37.700  66.911 1.00 11.42 ?  266  GLN B CB   1 
ATOM   9749  C CG   . GLN B 1 300 ? -6.443  36.984  66.920 1.00 10.63 ?  266  GLN B CG   1 
ATOM   9750  C CD   . GLN B 1 300 ? -6.566  35.949  68.018 1.00 11.21 ?  266  GLN B CD   1 
ATOM   9751  O OE1  . GLN B 1 300 ? -5.576  35.443  68.546 1.00 13.53 ?  266  GLN B OE1  1 
ATOM   9752  N NE2  . GLN B 1 300 ? -7.801  35.579  68.320 1.00 13.71 ?  266  GLN B NE2  1 
ATOM   9753  H H    . GLN B 1 300 ? -4.570  36.893  64.692 1.00 11.56 ?  266  GLN B H    1 
ATOM   9754  H HA   . GLN B 1 300 ? -5.732  39.055  65.502 1.00 11.33 ?  266  GLN B HA   1 
ATOM   9755  H HB2  . GLN B 1 300 ? -4.401  37.028  66.934 1.00 13.71 ?  266  GLN B HB2  1 
ATOM   9756  H HB3  . GLN B 1 300 ? -5.051  38.257  67.704 1.00 13.71 ?  266  GLN B HB3  1 
ATOM   9757  H HG2  . GLN B 1 300 ? -7.146  37.639  67.049 1.00 12.75 ?  266  GLN B HG2  1 
ATOM   9758  H HG3  . GLN B 1 300 ? -6.562  36.532  66.071 1.00 12.75 ?  266  GLN B HG3  1 
ATOM   9759  H HE21 . GLN B 1 300 ? -8.468  35.924  67.901 1.00 16.45 ?  266  GLN B HE21 1 
ATOM   9760  H HE22 . GLN B 1 300 ? -7.936  34.994  68.936 1.00 16.45 ?  266  GLN B HE22 1 
ATOM   9761  N N    . LYS B 1 301 ? -2.547  39.128  65.879 1.00 10.42 ?  267  LYS B N    1 
ATOM   9762  C CA   . LYS B 1 301 ? -1.424  40.026  66.133 1.00 10.91 ?  267  LYS B CA   1 
ATOM   9763  C C    . LYS B 1 301 ? -1.386  41.138  65.096 1.00 11.28 ?  267  LYS B C    1 
ATOM   9764  O O    . LYS B 1 301 ? -1.217  42.318  65.428 1.00 12.02 ?  267  LYS B O    1 
ATOM   9765  C CB   . LYS B 1 301 ? -0.107  39.251  66.142 1.00 12.63 ?  267  LYS B CB   1 
ATOM   9766  C CG   . LYS B 1 301 ? 0.242   38.625  67.476 1.00 28.99 ?  267  LYS B CG   1 
ATOM   9767  C CD   . LYS B 1 301 ? 0.947   37.286  67.323 1.00 34.78 ?  267  LYS B CD   1 
ATOM   9768  H H    . LYS B 1 301 ? -2.325  38.316  65.705 1.00 12.50 ?  267  LYS B H    1 
ATOM   9769  H HA   . LYS B 1 301 ? -1.535  40.423  67.011 1.00 13.09 ?  267  LYS B HA   1 
ATOM   9770  H HB2  . LYS B 1 301 ? -0.163  38.537  65.488 1.00 15.16 ?  267  LYS B HB2  1 
ATOM   9771  H HB3  . LYS B 1 301 ? 0.611   39.860  65.907 1.00 15.16 ?  267  LYS B HB3  1 
ATOM   9772  H HG2  . LYS B 1 301 ? 0.832   39.222  67.963 1.00 34.78 ?  267  LYS B HG2  1 
ATOM   9773  H HG3  . LYS B 1 301 ? -0.573  38.481  67.982 1.00 34.78 ?  267  LYS B HG3  1 
ATOM   9774  H HD3  . LYS B 1 301 ? 0.864   36.966  66.412 1.00 41.74 ?  267  LYS B HD3  1 
ATOM   9775  N N    . ALA B 1 302 ? -1.550  40.777  63.823 1.00 10.27 ?  268  ALA B N    1 
ATOM   9776  C CA   . ALA B 1 302 ? -1.510  41.773  62.758 1.00 11.21 ?  268  ALA B CA   1 
ATOM   9777  C C    . ALA B 1 302 ? -2.645  42.770  62.906 1.00 9.82  ?  268  ALA B C    1 
ATOM   9778  O O    . ALA B 1 302 ? -2.438  43.987  62.844 1.00 10.49 ?  268  ALA B O    1 
ATOM   9779  C CB   . ALA B 1 302 ? -1.597  41.073  61.400 1.00 9.50  ?  268  ALA B CB   1 
ATOM   9780  H H    . ALA B 1 302 ? -1.685  39.971  63.554 1.00 12.32 ?  268  ALA B H    1 
ATOM   9781  H HA   . ALA B 1 302 ? -0.669  42.255  62.806 1.00 13.45 ?  268  ALA B HA   1 
ATOM   9782  H HB1  . ALA B 1 302 ? -1.480  41.731  60.697 1.00 11.40 ?  268  ALA B HB1  1 
ATOM   9783  H HB2  . ALA B 1 302 ? -0.898  40.402  61.345 1.00 11.40 ?  268  ALA B HB2  1 
ATOM   9784  H HB3  . ALA B 1 302 ? -2.467  40.652  61.317 1.00 11.40 ?  268  ALA B HB3  1 
ATOM   9785  N N    . ALA B 1 303 ? -3.868  42.274  63.066 1.00 9.10  ?  269  ALA B N    1 
ATOM   9786  C CA   . ALA B 1 303 ? -5.029  43.155  63.180 1.00 9.32  ?  269  ALA B CA   1 
ATOM   9787  C C    . ALA B 1 303 ? -4.917  44.075  64.391 1.00 10.51 ?  269  ALA B C    1 
ATOM   9788  O O    . ALA B 1 303 ? -5.267  45.262  64.323 1.00 11.17 ?  269  ALA B O    1 
ATOM   9789  C CB   . ALA B 1 303 ? -6.317  42.325  63.230 1.00 11.58 ?  269  ALA B CB   1 
ATOM   9790  H H    . ALA B 1 303 ? -4.054  41.436  63.111 1.00 10.92 ?  269  ALA B H    1 
ATOM   9791  H HA   . ALA B 1 303 ? -5.072  43.718  62.391 1.00 11.19 ?  269  ALA B HA   1 
ATOM   9792  H HB1  . ALA B 1 303 ? -7.079  42.919  63.141 1.00 13.89 ?  269  ALA B HB1  1 
ATOM   9793  H HB2  . ALA B 1 303 ? -6.309  41.685  62.502 1.00 13.89 ?  269  ALA B HB2  1 
ATOM   9794  H HB3  . ALA B 1 303 ? -6.359  41.859  64.080 1.00 13.89 ?  269  ALA B HB3  1 
ATOM   9795  N N    . GLN B 1 304 ? -4.464  43.535  65.527 1.00 10.59 ?  270  GLN B N    1 
ATOM   9796  C CA   . GLN B 1 304 ? -4.334  44.355  66.726 1.00 11.08 ?  270  GLN B CA   1 
ATOM   9797  C C    . GLN B 1 304 ? -3.277  45.427  66.574 1.00 13.38 ?  270  GLN B C    1 
ATOM   9798  O O    . GLN B 1 304 ? -3.331  46.432  67.301 1.00 15.78 ?  270  GLN B O    1 
ATOM   9799  C CB   . GLN B 1 304 ? -4.068  43.463  67.931 1.00 12.39 ?  270  GLN B CB   1 
ATOM   9800  C CG   . GLN B 1 304 ? -5.297  42.627  68.289 1.00 14.33 ?  270  GLN B CG   1 
ATOM   9801  C CD   . GLN B 1 304 ? -5.017  41.468  69.226 1.00 16.33 ?  270  GLN B CD   1 
ATOM   9802  O OE1  . GLN B 1 304 ? -4.047  41.479  69.989 1.00 19.64 ?  270  GLN B OE1  1 
ATOM   9803  N NE2  . GLN B 1 304 ? -5.890  40.482  69.209 1.00 13.62 ?  270  GLN B NE2  1 
ATOM   9804  H H    . GLN B 1 304 ? -4.230  42.714  65.624 1.00 12.71 ?  270  GLN B H    1 
ATOM   9805  H HA   . GLN B 1 304 ? -5.170  44.816  66.899 1.00 13.30 ?  270  GLN B HA   1 
ATOM   9806  H HB2  . GLN B 1 304 ? -3.336  42.860  67.728 1.00 14.87 ?  270  GLN B HB2  1 
ATOM   9807  H HB3  . GLN B 1 304 ? -3.841  44.015  68.695 1.00 14.87 ?  270  GLN B HB3  1 
ATOM   9808  H HG2  . GLN B 1 304 ? -5.947  43.202  68.721 1.00 17.20 ?  270  GLN B HG2  1 
ATOM   9809  H HG3  . GLN B 1 304 ? -5.669  42.260  67.472 1.00 17.20 ?  270  GLN B HG3  1 
ATOM   9810  H HE21 . GLN B 1 304 ? -6.571  40.521  68.685 1.00 16.34 ?  270  GLN B HE21 1 
ATOM   9811  H HE22 . GLN B 1 304 ? -5.779  39.800  69.721 1.00 16.34 ?  270  GLN B HE22 1 
ATOM   9812  N N    . SER B 1 305 ? -2.329  45.257  65.656 1.00 11.41 ?  271  SER B N    1 
ATOM   9813  C CA   . SER B 1 305 ? -1.318  46.272  65.394 1.00 12.93 ?  271  SER B CA   1 
ATOM   9814  C C    . SER B 1 305 ? -1.798  47.364  64.450 1.00 13.87 ?  271  SER B C    1 
ATOM   9815  O O    . SER B 1 305 ? -1.047  48.311  64.189 1.00 14.92 ?  271  SER B O    1 
ATOM   9816  C CB   . SER B 1 305 ? -0.052  45.614  64.846 1.00 12.95 ?  271  SER B CB   1 
ATOM   9817  O OG   . SER B 1 305 ? -0.167  45.278  63.467 1.00 14.16 ?  271  SER B OG   1 
ATOM   9818  H H    . SER B 1 305 ? -2.251  44.554  65.167 1.00 13.69 ?  271  SER B H    1 
ATOM   9819  H HA   . SER B 1 305 ? -1.084  46.703  66.231 1.00 15.52 ?  271  SER B HA   1 
ATOM   9820  H HB2  . SER B 1 305 ? 0.689   46.231  64.953 1.00 15.54 ?  271  SER B HB2  1 
ATOM   9821  H HB3  . SER B 1 305 ? 0.118   44.802  65.349 1.00 15.54 ?  271  SER B HB3  1 
ATOM   9822  H HG   . SER B 1 305 ? -0.117  44.445  63.369 1.00 16.99 ?  271  SER B HG   1 
ATOM   9823  N N    . GLY B 1 306 ? -3.004  47.249  63.911 1.00 11.57 ?  272  GLY B N    1 
ATOM   9824  C CA   . GLY B 1 306 ? -3.523  48.246  63.008 1.00 11.64 ?  272  GLY B CA   1 
ATOM   9825  C C    . GLY B 1 306 ? -3.364  47.931  61.540 1.00 11.64 ?  272  GLY B C    1 
ATOM   9826  O O    . GLY B 1 306 ? -3.630  48.805  60.704 1.00 13.31 ?  272  GLY B O    1 
ATOM   9827  H H    . GLY B 1 306 ? -3.541  46.594  64.059 1.00 13.89 ?  272  GLY B H    1 
ATOM   9828  H HA2  . GLY B 1 306 ? -4.470  48.359  63.183 1.00 13.96 ?  272  GLY B HA2  1 
ATOM   9829  H HA3  . GLY B 1 306 ? -3.067  49.085  63.179 1.00 13.96 ?  272  GLY B HA3  1 
ATOM   9830  N N    . LYS B 1 307 ? -2.924  46.726  61.199 1.00 11.05 ?  273  LYS B N    1 
ATOM   9831  C CA   . LYS B 1 307 ? -2.818  46.323  59.804 1.00 10.43 ?  273  LYS B CA   1 
ATOM   9832  C C    . LYS B 1 307 ? -4.177  45.896  59.268 1.00 9.91  ?  273  LYS B C    1 
ATOM   9833  O O    . LYS B 1 307 ? -4.985  45.294  59.984 1.00 9.96  ?  273  LYS B O    1 
ATOM   9834  C CB   . LYS B 1 307 ? -1.836  45.164  59.654 1.00 11.28 ?  273  LYS B CB   1 
ATOM   9835  C CG   . LYS B 1 307 ? -0.400  45.470  60.069 1.00 13.20 ?  273  LYS B CG   1 
ATOM   9836  C CD   . LYS B 1 307 ? 0.330   46.267  59.025 1.00 14.99 ?  273  LYS B CD   1 
ATOM   9837  C CE   . LYS B 1 307 ? 1.750   46.509  59.515 1.00 19.02 ?  273  LYS B CE   1 
ATOM   9838  N NZ   . LYS B 1 307 ? 2.545   47.299  58.566 1.00 19.21 ?  273  LYS B NZ   1 
ATOM   9839  H H    . LYS B 1 307 ? -2.679  46.121  61.759 1.00 13.26 ?  273  LYS B H    1 
ATOM   9840  H HA   . LYS B 1 307 ? -2.496  47.075  59.283 1.00 12.51 ?  273  LYS B HA   1 
ATOM   9841  H HB2  . LYS B 1 307 ? -2.146  44.427  60.204 1.00 13.53 ?  273  LYS B HB2  1 
ATOM   9842  H HB3  . LYS B 1 307 ? -1.818  44.897  58.722 1.00 13.53 ?  273  LYS B HB3  1 
ATOM   9843  H HG2  . LYS B 1 307 ? -0.408  45.984  60.891 1.00 15.84 ?  273  LYS B HG2  1 
ATOM   9844  H HG3  . LYS B 1 307 ? 0.078   44.637  60.203 1.00 15.84 ?  273  LYS B HG3  1 
ATOM   9845  H HD2  . LYS B 1 307 ? 0.361   45.774  58.191 1.00 17.99 ?  273  LYS B HD2  1 
ATOM   9846  H HD3  . LYS B 1 307 ? -0.110  47.121  58.890 1.00 17.99 ?  273  LYS B HD3  1 
ATOM   9847  H HE2  . LYS B 1 307 ? 1.717   46.992  60.355 1.00 22.83 ?  273  LYS B HE2  1 
ATOM   9848  H HE3  . LYS B 1 307 ? 2.192   45.655  59.639 1.00 22.83 ?  273  LYS B HE3  1 
ATOM   9849  H HZ1  . LYS B 1 307 ? 2.603   46.872  57.788 1.00 23.06 ?  273  LYS B HZ1  1 
ATOM   9850  H HZ2  . LYS B 1 307 ? 2.162   48.091  58.433 1.00 23.06 ?  273  LYS B HZ2  1 
ATOM   9851  H HZ3  . LYS B 1 307 ? 3.365   47.426  58.888 1.00 23.06 ?  273  LYS B HZ3  1 
ATOM   9852  N N    . ILE B 1 308 ? -4.408  46.203  57.985 1.00 9.69  ?  274  ILE B N    1 
ATOM   9853  C CA   . ILE B 1 308 ? -5.603  45.727  57.290 1.00 8.78  ?  274  ILE B CA   1 
ATOM   9854  C C    . ILE B 1 308 ? -5.529  44.211  57.157 1.00 8.27  ?  274  ILE B C    1 
ATOM   9855  O O    . ILE B 1 308 ? -4.460  43.647  56.877 1.00 9.02  ?  274  ILE B O    1 
ATOM   9856  C CB   . ILE B 1 308 ? -5.719  46.389  55.906 1.00 9.43  ?  274  ILE B CB   1 
ATOM   9857  C CG1  . ILE B 1 308 ? -5.867  47.908  56.067 1.00 10.86 ?  274  ILE B CG1  1 
ATOM   9858  C CG2  . ILE B 1 308 ? -6.896  45.788  55.131 1.00 8.39  ?  274  ILE B CG2  1 
ATOM   9859  C CD1  . ILE B 1 308 ? -5.675  48.704  54.779 1.00 11.14 ?  274  ILE B CD1  1 
ATOM   9860  H H    . ILE B 1 308 ? -3.888  46.684  57.498 1.00 11.62 ?  274  ILE B H    1 
ATOM   9861  H HA   . ILE B 1 308 ? -6.390  45.964  57.806 1.00 10.53 ?  274  ILE B HA   1 
ATOM   9862  H HB   . ILE B 1 308 ? -4.910  46.217  55.400 1.00 11.32 ?  274  ILE B HB   1 
ATOM   9863  H HG12 . ILE B 1 308 ? -6.759  48.098  56.398 1.00 13.03 ?  274  ILE B HG12 1 
ATOM   9864  H HG13 . ILE B 1 308 ? -5.204  48.217  56.703 1.00 13.03 ?  274  ILE B HG13 1 
ATOM   9865  H HG21 . ILE B 1 308 ? -7.083  46.346  54.360 1.00 10.06 ?  274  ILE B HG21 1 
ATOM   9866  H HG22 . ILE B 1 308 ? -6.659  44.893  54.842 1.00 10.06 ?  274  ILE B HG22 1 
ATOM   9867  H HG23 . ILE B 1 308 ? -7.672  45.754  55.711 1.00 10.06 ?  274  ILE B HG23 1 
ATOM   9868  H HD11 . ILE B 1 308 ? -5.607  49.647  54.998 1.00 13.36 ?  274  ILE B HD11 1 
ATOM   9869  H HD12 . ILE B 1 308 ? -4.862  48.407  54.342 1.00 13.36 ?  274  ILE B HD12 1 
ATOM   9870  H HD13 . ILE B 1 308 ? -6.437  48.554  54.198 1.00 13.36 ?  274  ILE B HD13 1 
ATOM   9871  N N    . ILE B 1 309 ? -6.663  43.537  57.365 1.00 8.18  ?  275  ILE B N    1 
ATOM   9872  C CA   . ILE B 1 309 ? -6.789  42.111  57.079 1.00 8.86  ?  275  ILE B CA   1 
ATOM   9873  C C    . ILE B 1 309 ? -7.947  41.917  56.121 1.00 8.10  ?  275  ILE B C    1 
ATOM   9874  O O    . ILE B 1 309 ? -9.048  42.417  56.369 1.00 7.86  ?  275  ILE B O    1 
ATOM   9875  C CB   . ILE B 1 309 ? -7.034  41.300  58.362 1.00 8.68  ?  275  ILE B CB   1 
ATOM   9876  C CG1  . ILE B 1 309 ? -5.795  41.299  59.271 1.00 9.63  ?  275  ILE B CG1  1 
ATOM   9877  C CG2  . ILE B 1 309 ? -7.469  39.878  58.049 1.00 10.54 ?  275  ILE B CG2  1 
ATOM   9878  C CD1  . ILE B 1 309 ? -4.541  40.644  58.688 1.00 11.00 ?  275  ILE B CD1  1 
ATOM   9879  H H    . ILE B 1 309 ? -7.382  43.893  57.675 1.00 9.82  ?  275  ILE B H    1 
ATOM   9880  H HA   . ILE B 1 309 ? -5.973  41.799  56.657 1.00 10.64 ?  275  ILE B HA   1 
ATOM   9881  H HB   . ILE B 1 309 ? -7.757  41.737  58.839 1.00 10.42 ?  275  ILE B HB   1 
ATOM   9882  H HG12 . ILE B 1 309 ? -5.569  42.220  59.477 1.00 11.55 ?  275  ILE B HG12 1 
ATOM   9883  H HG13 . ILE B 1 309 ? -6.016  40.822  60.086 1.00 11.55 ?  275  ILE B HG13 1 
ATOM   9884  H HG21 . ILE B 1 309 ? -7.346  39.328  58.839 1.00 12.65 ?  275  ILE B HG21 1 
ATOM   9885  H HG22 . ILE B 1 309 ? -8.404  39.883  57.792 1.00 12.65 ?  275  ILE B HG22 1 
ATOM   9886  H HG23 . ILE B 1 309 ? -6.927  39.535  57.320 1.00 12.65 ?  275  ILE B HG23 1 
ATOM   9887  H HD11 . ILE B 1 309 ? -3.845  40.638  59.364 1.00 13.20 ?  275  ILE B HD11 1 
ATOM   9888  H HD12 . ILE B 1 309 ? -4.753  39.735  58.424 1.00 13.20 ?  275  ILE B HD12 1 
ATOM   9889  H HD13 . ILE B 1 309 ? -4.248  41.153  57.916 1.00 13.20 ?  275  ILE B HD13 1 
ATOM   9890  N N    . THR B 1 310 ? -7.723  41.156  55.052 1.00 7.54  ?  276  THR B N    1 
ATOM   9891  C CA   . THR B 1 310 ? -8.803  40.731  54.158 1.00 8.07  ?  276  THR B CA   1 
ATOM   9892  C C    . THR B 1 310 ? -8.802  39.202  54.160 1.00 7.96  ?  276  THR B C    1 
ATOM   9893  O O    . THR B 1 310 ? -8.022  38.563  53.452 1.00 8.68  ?  276  THR B O    1 
ATOM   9894  C CB   . THR B 1 310 ? -8.709  41.354  52.758 1.00 8.27  ?  276  THR B CB   1 
ATOM   9895  O OG1  . THR B 1 310 ? -7.540  40.888  52.079 1.00 8.58  ?  276  THR B OG1  1 
ATOM   9896  C CG2  . THR B 1 310 ? -8.630  42.878  52.809 1.00 8.79  ?  276  THR B CG2  1 
ATOM   9897  H H    . THR B 1 310 ? -6.945  40.871  54.820 1.00 9.04  ?  276  THR B H    1 
ATOM   9898  H HA   . THR B 1 310 ? -9.653  41.036  54.512 1.00 9.69  ?  276  THR B HA   1 
ATOM   9899  H HB   . THR B 1 310 ? -9.511  41.097  52.277 1.00 9.93  ?  276  THR B HB   1 
ATOM   9900  H HG1  . THR B 1 310 ? -7.626  40.075  51.885 1.00 10.30 ?  276  THR B HG1  1 
ATOM   9901  H HG21 . THR B 1 310 ? -8.560  43.237  51.910 1.00 10.54 ?  276  THR B HG21 1 
ATOM   9902  H HG22 . THR B 1 310 ? -9.426  43.238  53.230 1.00 10.54 ?  276  THR B HG22 1 
ATOM   9903  H HG23 . THR B 1 310 ? -7.852  43.153  53.319 1.00 10.54 ?  276  THR B HG23 1 
ATOM   9904  N N    . MET B 1 311 ? -9.616  38.636  55.022 1.00 8.07  ?  277  MET B N    1 
ATOM   9905  C CA   . MET B 1 311 ? -9.776  37.208  55.128 1.00 7.69  ?  277  MET B CA   1 
ATOM   9906  C C    . MET B 1 311 ? -10.660 36.618  54.048 1.00 7.80  ?  277  MET B C    1 
ATOM   9907  O O    . MET B 1 311 ? -11.862 36.892  54.019 1.00 8.84  ?  277  MET B O    1 
ATOM   9908  C CB   . MET B 1 311 ? -10.467 36.730  56.401 1.00 10.81 ?  277  MET B CB   1 
ATOM   9909  C CG   . MET B 1 311 ? -10.000 35.364  56.886 1.00 10.18 ?  277  MET B CG   1 
ATOM   9910  S SD   . MET B 1 311 ? -10.751 34.793  58.418 1.00 9.70  ?  277  MET B SD   1 
ATOM   9911  C CE   . MET B 1 311 ? -9.416  35.469  59.556 1.00 11.17 ?  277  MET B CE   1 
ATOM   9912  H H    . MET B 1 311 ? -10.105 39.074  55.578 1.00 9.69  ?  277  MET B H    1 
ATOM   9913  H HA   . MET B 1 311 ? -8.850  36.922  55.083 1.00 9.23  ?  277  MET B HA   1 
ATOM   9914  H HB2  . MET B 1 311 ? -10.292 37.370  57.109 1.00 12.97 ?  277  MET B HB2  1 
ATOM   9915  H HB3  . MET B 1 311 ? -11.421 36.673  56.234 1.00 12.97 ?  277  MET B HB3  1 
ATOM   9916  H HG2  . MET B 1 311 ? -10.206 34.709  56.202 1.00 12.21 ?  277  MET B HG2  1 
ATOM   9917  H HG3  . MET B 1 311 ? -9.041  35.403  57.031 1.00 12.21 ?  277  MET B HG3  1 
ATOM   9918  H HE1  . MET B 1 311 ? -9.641  35.248  60.473 1.00 13.40 ?  277  MET B HE1  1 
ATOM   9919  H HE2  . MET B 1 311 ? -8.566  35.068  59.318 1.00 13.40 ?  277  MET B HE2  1 
ATOM   9920  H HE3  . MET B 1 311 ? -9.369  36.432  59.450 1.00 13.40 ?  277  MET B HE3  1 
ATOM   9921  N N    . THR B 1 312 ? -10.110 35.733  53.221 1.00 7.77  ?  278  THR B N    1 
ATOM   9922  C CA   . THR B 1 312 ? -10.917 34.993  52.252 1.00 7.71  ?  278  THR B CA   1 
ATOM   9923  C C    . THR B 1 312 ? -11.018 33.547  52.715 1.00 8.26  ?  278  THR B C    1 
ATOM   9924  O O    . THR B 1 312 ? -10.027 32.962  53.176 1.00 9.12  ?  278  THR B O    1 
ATOM   9925  C CB   . THR B 1 312 ? -10.397 35.106  50.803 1.00 8.22  ?  278  THR B CB   1 
ATOM   9926  O OG1  . THR B 1 312 ? -9.184  34.358  50.619 1.00 8.35  ?  278  THR B OG1  1 
ATOM   9927  C CG2  . THR B 1 312 ? -10.174 36.558  50.457 1.00 8.79  ?  278  THR B CG2  1 
ATOM   9928  H H    . THR B 1 312 ? -9.271  35.543  53.202 1.00 9.33  ?  278  THR B H    1 
ATOM   9929  H HA   . THR B 1 312 ? -11.810 35.370  52.217 1.00 9.26  ?  278  THR B HA   1 
ATOM   9930  H HB   . THR B 1 312 ? -11.058 34.734  50.199 1.00 9.86  ?  278  THR B HB   1 
ATOM   9931  H HG1  . THR B 1 312 ? -8.676  34.467  51.280 1.00 10.02 ?  278  THR B HG1  1 
ATOM   9932  H HG21 . THR B 1 312 ? -10.063 36.658  49.498 1.00 10.55 ?  278  THR B HG21 1 
ATOM   9933  H HG22 . THR B 1 312 ? -10.935 37.089  50.742 1.00 10.55 ?  278  THR B HG22 1 
ATOM   9934  H HG23 . THR B 1 312 ? -9.377  36.887  50.902 1.00 10.55 ?  278  THR B HG23 1 
ATOM   9935  N N    . LEU B 1 313 ? -12.223 32.989  52.628 1.00 7.76  ?  279  LEU B N    1 
ATOM   9936  C CA   . LEU B 1 313 ? -12.519 31.618  53.021 1.00 8.69  ?  279  LEU B CA   1 
ATOM   9937  C C    . LEU B 1 313 ? -13.450 31.035  51.972 1.00 7.86  ?  279  LEU B C    1 
ATOM   9938  O O    . LEU B 1 313 ? -14.473 31.641  51.633 1.00 8.08  ?  279  LEU B O    1 
ATOM   9939  C CB   . LEU B 1 313 ? -13.174 31.562  54.402 1.00 8.97  ?  279  LEU B CB   1 
ATOM   9940  C CG   . LEU B 1 313 ? -12.250 31.960  55.565 1.00 11.79 ?  279  LEU B CG   1 
ATOM   9941  C CD1  . LEU B 1 313 ? -13.075 32.232  56.810 1.00 12.90 ?  279  LEU B CD1  1 
ATOM   9942  C CD2  . LEU B 1 313 ? -11.195 30.911  55.834 1.00 15.00 ?  279  LEU B CD2  1 
ATOM   9943  H H    . LEU B 1 313 ? -12.915 33.405  52.330 1.00 9.31  ?  279  LEU B H    1 
ATOM   9944  H HA   . LEU B 1 313 ? -11.705 31.093  53.061 1.00 10.43 ?  279  LEU B HA   1 
ATOM   9945  H HB2  . LEU B 1 313 ? -13.931 32.169  54.409 1.00 10.77 ?  279  LEU B HB2  1 
ATOM   9946  H HB3  . LEU B 1 313 ? -13.475 30.655  54.564 1.00 10.77 ?  279  LEU B HB3  1 
ATOM   9947  H HG   . LEU B 1 313 ? -11.777 32.770  55.320 1.00 14.15 ?  279  LEU B HG   1 
ATOM   9948  H HD11 . LEU B 1 313 ? -12.487 32.543  57.517 1.00 15.48 ?  279  LEU B HD11 1 
ATOM   9949  H HD12 . LEU B 1 313 ? -13.737 32.912  56.608 1.00 15.48 ?  279  LEU B HD12 1 
ATOM   9950  H HD13 . LEU B 1 313 ? -13.516 31.412  57.083 1.00 15.48 ?  279  LEU B HD13 1 
ATOM   9951  H HD21 . LEU B 1 313 ? -10.632 31.210  56.565 1.00 18.01 ?  279  LEU B HD21 1 
ATOM   9952  H HD22 . LEU B 1 313 ? -11.631 30.078  56.071 1.00 18.01 ?  279  LEU B HD22 1 
ATOM   9953  H HD23 . LEU B 1 313 ? -10.660 30.789  55.034 1.00 18.01 ?  279  LEU B HD23 1 
ATOM   9954  N N    . GLY B 1 314 ? -13.102 29.863  51.454 1.00 8.78  ?  280  GLY B N    1 
ATOM   9955  C CA   . GLY B 1 314 ? -13.900 29.261  50.405 1.00 9.42  ?  280  GLY B CA   1 
ATOM   9956  C C    . GLY B 1 314 ? -15.116 28.535  50.946 1.00 10.55 ?  280  GLY B C    1 
ATOM   9957  O O    . GLY B 1 314 ? -15.033 27.806  51.934 1.00 12.29 ?  280  GLY B O    1 
ATOM   9958  H H    . GLY B 1 314 ? -12.415 29.403  51.692 1.00 10.54 ?  280  GLY B H    1 
ATOM   9959  H HA2  . GLY B 1 314 ? -14.204 29.952  49.796 1.00 11.30 ?  280  GLY B HA2  1 
ATOM   9960  H HA3  . GLY B 1 314 ? -13.358 28.624  49.914 1.00 11.30 ?  280  GLY B HA3  1 
ATOM   9961  N N    . LEU B 1 315 ? -16.250 28.743  50.267 1.00 10.43 ?  281  LEU B N    1 
ATOM   9962  C CA   . LEU B 1 315 ? -17.481 27.963  50.378 1.00 13.58 ?  281  LEU B CA   1 
ATOM   9963  C C    . LEU B 1 315 ? -17.622 26.955  49.239 1.00 18.29 ?  281  LEU B C    1 
ATOM   9964  O O    . LEU B 1 315 ? -18.629 26.237  49.182 1.00 19.10 ?  281  LEU B O    1 
ATOM   9965  C CB   . LEU B 1 315 ? -18.682 28.886  50.222 1.00 12.03 ?  281  LEU B CB   1 
ATOM   9966  C CG   . LEU B 1 315 ? -19.017 29.870  51.314 1.00 13.82 ?  281  LEU B CG   1 
ATOM   9967  C CD1  . LEU B 1 315 ? -20.027 30.876  50.762 1.00 22.14 ?  281  LEU B CD1  1 
ATOM   9968  C CD2  . LEU B 1 315 ? -19.566 29.161  52.520 1.00 20.21 ?  281  LEU B CD2  1 
ATOM   9969  H H    . LEU B 1 315 ? -16.334 29.378  49.693 1.00 12.51 ?  281  LEU B H    1 
ATOM   9970  H HA   . LEU B 1 315 ? -17.480 27.525  51.243 1.00 16.30 ?  281  LEU B HA   1 
ATOM   9971  H HB2  . LEU B 1 315 ? -18.539 29.411  49.419 1.00 14.44 ?  281  LEU B HB2  1 
ATOM   9972  H HB3  . LEU B 1 315 ? -19.465 28.323  50.115 1.00 14.44 ?  281  LEU B HB3  1 
ATOM   9973  H HG   . LEU B 1 315 ? -18.220 30.341  51.602 1.00 16.58 ?  281  LEU B HG   1 
ATOM   9974  H HD11 . LEU B 1 315 ? -20.448 31.340  51.503 1.00 26.57 ?  281  LEU B HD11 1 
ATOM   9975  H HD12 . LEU B 1 315 ? -19.563 31.511  50.195 1.00 26.57 ?  281  LEU B HD12 1 
ATOM   9976  H HD13 . LEU B 1 315 ? -20.697 30.400  50.247 1.00 26.57 ?  281  LEU B HD13 1 
ATOM   9977  H HD21 . LEU B 1 315 ? -19.815 29.819  53.187 1.00 24.26 ?  281  LEU B HD21 1 
ATOM   9978  H HD22 . LEU B 1 315 ? -20.344 28.646  52.256 1.00 24.26 ?  281  LEU B HD22 1 
ATOM   9979  H HD23 . LEU B 1 315 ? -18.884 28.571  52.876 1.00 24.26 ?  281  LEU B HD23 1 
ATOM   9980  N N    . GLY B 1 316 ? -16.655 26.894  48.320 1.00 20.31 ?  282  GLY B N    1 
ATOM   9981  C CA   . GLY B 1 316 ? -16.811 26.060  47.134 1.00 21.48 ?  282  GLY B CA   1 
ATOM   9982  C C    . GLY B 1 316 ? -17.141 24.614  47.442 1.00 25.58 ?  282  GLY B C    1 
ATOM   9983  O O    . GLY B 1 316 ? -17.931 23.988  46.731 1.00 25.77 ?  282  GLY B O    1 
ATOM   9984  H H    . GLY B 1 316 ? -15.910 27.321  48.360 1.00 24.37 ?  282  GLY B H    1 
ATOM   9985  H HA2  . GLY B 1 316 ? -17.527 26.420  46.587 1.00 25.77 ?  282  GLY B HA2  1 
ATOM   9986  H HA3  . GLY B 1 316 ? -15.986 26.077  46.625 1.00 25.77 ?  282  GLY B HA3  1 
ATOM   9987  N N    . GLU B 1 317 ? -16.553 24.064  48.510 1.00 26.22 ?  283  GLU B N    1 
ATOM   9988  C CA   . GLU B 1 317 ? -16.782 22.661  48.843 1.00 36.30 ?  283  GLU B CA   1 
ATOM   9989  C C    . GLU B 1 317 ? -18.155 22.421  49.462 1.00 38.11 ?  283  GLU B C    1 
ATOM   9990  O O    . GLU B 1 317 ? -18.744 21.360  49.247 1.00 37.65 ?  283  GLU B O    1 
ATOM   9991  C CB   . GLU B 1 317 ? -15.688 22.141  49.777 1.00 43.66 ?  283  GLU B CB   1 
ATOM   9992  C CG   . GLU B 1 317 ? -15.241 20.724  49.449 1.00 58.17 ?  283  GLU B CG   1 
ATOM   9993  C CD   . GLU B 1 317 ? -16.320 19.692  49.744 1.00 62.23 ?  283  GLU B CD   1 
ATOM   9994  O OE1  . GLU B 1 317 ? -16.916 19.752  50.842 1.00 58.95 ?  283  GLU B OE1  1 
ATOM   9995  O OE2  . GLU B 1 317 ? -16.574 18.828  48.875 1.00 59.30 ?  283  GLU B OE2  1 
ATOM   9996  H H    . GLU B 1 317 ? -16.025 24.478  49.049 1.00 31.47 ?  283  GLU B H    1 
ATOM   9997  H HA   . GLU B 1 317 ? -16.735 22.148  48.021 1.00 43.57 ?  283  GLU B HA   1 
ATOM   9998  H HB2  . GLU B 1 317 ? -14.914 22.722  49.708 1.00 52.39 ?  283  GLU B HB2  1 
ATOM   9999  H HB3  . GLU B 1 317 ? -16.025 22.144  50.687 1.00 52.39 ?  283  GLU B HB3  1 
ATOM   10000 H HG2  . GLU B 1 317 ? -15.023 20.671  48.506 1.00 69.80 ?  283  GLU B HG2  1 
ATOM   10001 H HG3  . GLU B 1 317 ? -14.461 20.506  49.983 1.00 69.80 ?  283  GLU B HG3  1 
ATOM   10002 N N    . ALA B 1 318 ? -18.680 23.379  50.224 1.00 27.37 ?  284  ALA B N    1 
ATOM   10003 C CA   . ALA B 1 318 ? -20.022 23.244  50.777 1.00 18.39 ?  284  ALA B CA   1 
ATOM   10004 C C    . ALA B 1 318 ? -21.105 23.555  49.749 1.00 29.45 ?  284  ALA B C    1 
ATOM   10005 O O    . ALA B 1 318 ? -22.265 23.175  49.949 1.00 38.45 ?  284  ALA B O    1 
ATOM   10006 C CB   . ALA B 1 318 ? -20.184 24.219  51.949 1.00 24.47 ?  284  ALA B CB   1 
ATOM   10007 H H    . ALA B 1 318 ? -18.281 24.111  50.433 1.00 32.85 ?  284  ALA B H    1 
ATOM   10008 H HA   . ALA B 1 318 ? -20.143 22.336  51.094 1.00 22.07 ?  284  ALA B HA   1 
ATOM   10009 H HB1  . ALA B 1 318 ? -21.079 24.130  52.313 1.00 29.36 ?  284  ALA B HB1  1 
ATOM   10010 H HB2  . ALA B 1 318 ? -19.528 24.006  52.630 1.00 29.36 ?  284  ALA B HB2  1 
ATOM   10011 H HB3  . ALA B 1 318 ? -20.047 25.124  51.628 1.00 29.36 ?  284  ALA B HB3  1 
ATOM   10012 N N    . ILE B 1 319 ? -20.745 24.257  48.677 1.00 21.08 ?  285  ILE B N    1 
ATOM   10013 C CA   . ILE B 1 319 ? -21.656 24.589  47.581 1.00 24.41 ?  285  ILE B CA   1 
ATOM   10014 C C    . ILE B 1 319 ? -21.668 23.519  46.492 1.00 25.71 ?  285  ILE B C    1 
ATOM   10015 O O    . ILE B 1 319 ? -22.700 23.310  45.837 1.00 21.09 ?  285  ILE B O    1 
ATOM   10016 C CB   . ILE B 1 319 ? -21.184 25.936  47.000 1.00 25.96 ?  285  ILE B CB   1 
ATOM   10017 C CG1  . ILE B 1 319 ? -21.656 27.084  47.884 1.00 30.79 ?  285  ILE B CG1  1 
ATOM   10018 C CG2  . ILE B 1 319 ? -21.649 26.091  45.538 1.00 37.31 ?  285  ILE B CG2  1 
ATOM   10019 C CD1  . ILE B 1 319 ? -21.139 28.442  47.449 1.00 35.04 ?  285  ILE B CD1  1 
ATOM   10020 H H    . ILE B 1 319 ? -19.951 24.564  48.554 1.00 25.29 ?  285  ILE B H    1 
ATOM   10021 H HA   . ILE B 1 319 ? -22.565 24.656  47.911 1.00 29.29 ?  285  ILE B HA   1 
ATOM   10022 H HB   . ILE B 1 319 ? -20.214 25.954  46.992 1.00 31.15 ?  285  ILE B HB   1 
ATOM   10023 H HG12 . ILE B 1 319 ? -22.625 27.116  47.864 1.00 36.95 ?  285  ILE B HG12 1 
ATOM   10024 H HG13 . ILE B 1 319 ? -21.349 26.927  48.791 1.00 36.95 ?  285  ILE B HG13 1 
ATOM   10025 H HG21 . ILE B 1 319 ? -21.381 26.965  45.213 1.00 44.77 ?  285  ILE B HG21 1 
ATOM   10026 H HG22 . ILE B 1 319 ? -21.237 25.397  45.000 1.00 44.77 ?  285  ILE B HG22 1 
ATOM   10027 H HG23 . ILE B 1 319 ? -22.615 26.007  45.504 1.00 44.77 ?  285  ILE B HG23 1 
ATOM   10028 H HD11 . ILE B 1 319 ? -21.464 29.117  48.066 1.00 42.05 ?  285  ILE B HD11 1 
ATOM   10029 H HD12 . ILE B 1 319 ? -20.169 28.428  47.456 1.00 42.05 ?  285  ILE B HD12 1 
ATOM   10030 H HD13 . ILE B 1 319 ? -21.461 28.631  46.554 1.00 42.05 ?  285  ILE B HD13 1 
ATOM   10031 N N    . ASP B 1 320 ? -20.536 22.884  46.227 1.00 25.80 ?  286  ASP B N    1 
ATOM   10032 C CA   . ASP B 1 320 ? -20.472 21.922  45.138 1.00 25.20 ?  286  ASP B CA   1 
ATOM   10033 C C    . ASP B 1 320 ? -21.537 20.854  45.346 1.00 26.11 ?  286  ASP B C    1 
ATOM   10034 O O    . ASP B 1 320 ? -21.768 20.399  46.468 1.00 26.14 ?  286  ASP B O    1 
ATOM   10035 C CB   . ASP B 1 320 ? -19.082 21.287  45.084 1.00 31.02 ?  286  ASP B CB   1 
ATOM   10036 H H    . ASP B 1 320 ? -19.799 22.990  46.657 1.00 30.96 ?  286  ASP B H    1 
ATOM   10037 H HA   . ASP B 1 320 ? -20.632 22.362  44.288 1.00 30.24 ?  286  ASP B HA   1 
ATOM   10038 H HB2  . ASP B 1 320 ? -18.437 21.965  44.826 1.00 37.23 ?  286  ASP B HB2  1 
ATOM   10039 H HB3  . ASP B 1 320 ? -18.859 20.932  45.957 1.00 37.23 ?  286  ASP B HB3  1 
ATOM   10040 N N    . ASN B 1 321 ? -22.204 20.461  44.249 1.00 23.40 ?  287  ASN B N    1 
ATOM   10041 C CA   . ASN B 1 321 ? -23.336 19.540  44.326 1.00 20.36 ?  287  ASN B CA   1 
ATOM   10042 C C    . ASN B 1 321 ? -23.277 18.444  43.261 1.00 25.14 ?  287  ASN B C    1 
ATOM   10043 O O    . ASN B 1 321 ? -24.312 17.836  42.954 1.00 23.41 ?  287  ASN B O    1 
ATOM   10044 C CB   . ASN B 1 321 ? -24.675 20.308  44.270 1.00 20.18 ?  287  ASN B CB   1 
ATOM   10045 C CG   . ASN B 1 321 ? -24.826 21.122  43.010 1.00 18.47 ?  287  ASN B CG   1 
ATOM   10046 O OD1  . ASN B 1 321 ? -24.082 20.926  42.041 1.00 21.32 ?  287  ASN B OD1  1 
ATOM   10047 N ND2  . ASN B 1 321 ? -25.780 22.045  43.013 1.00 22.07 ?  287  ASN B ND2  1 
ATOM   10048 H H    . ASN B 1 321 ? -22.017 20.717  43.450 1.00 28.08 ?  287  ASN B H    1 
ATOM   10049 H HA   . ASN B 1 321 ? -23.308 19.083  45.181 1.00 24.43 ?  287  ASN B HA   1 
ATOM   10050 H HB2  . ASN B 1 321 ? -25.406 19.672  44.306 1.00 24.22 ?  287  ASN B HB2  1 
ATOM   10051 H HB3  . ASN B 1 321 ? -24.725 20.913  45.026 1.00 24.22 ?  287  ASN B HB3  1 
ATOM   10052 H HD21 . ASN B 1 321 ? -25.905 22.535  42.317 1.00 26.49 ?  287  ASN B HD21 1 
ATOM   10053 H HD22 . ASN B 1 321 ? -26.272 22.152  43.709 1.00 26.49 ?  287  ASN B HD22 1 
ATOM   10054 N N    . ASN B 1 322 ? -22.093 18.164  42.715 1.00 23.21 ?  288  ASN B N    1 
ATOM   10055 C CA   . ASN B 1 322 ? -21.887 17.083  41.746 1.00 24.99 ?  288  ASN B CA   1 
ATOM   10056 C C    . ASN B 1 322 ? -22.697 17.278  40.465 1.00 25.65 ?  288  ASN B C    1 
ATOM   10057 O O    . ASN B 1 322 ? -23.178 16.311  39.870 1.00 24.81 ?  288  ASN B O    1 
ATOM   10058 C CB   . ASN B 1 322 ? -22.169 15.693  42.332 1.00 35.21 ?  288  ASN B CB   1 
ATOM   10059 C CG   . ASN B 1 322 ? -21.098 15.229  43.292 1.00 44.14 ?  288  ASN B CG   1 
ATOM   10060 O OD1  . ASN B 1 322 ? -19.929 15.581  43.150 1.00 46.20 ?  288  ASN B OD1  1 
ATOM   10061 N ND2  . ASN B 1 322 ? -21.484 14.385  44.245 1.00 46.98 ?  288  ASN B ND2  1 
ATOM   10062 H H    . ASN B 1 322 ? -21.372 18.598  42.894 1.00 27.85 ?  288  ASN B H    1 
ATOM   10063 H HA   . ASN B 1 322 ? -20.947 17.121  41.510 1.00 29.99 ?  288  ASN B HA   1 
ATOM   10064 H HB2  . ASN B 1 322 ? -23.011 15.718  42.813 1.00 42.25 ?  288  ASN B HB2  1 
ATOM   10065 H HB3  . ASN B 1 322 ? -22.220 15.050  41.607 1.00 42.25 ?  288  ASN B HB3  1 
ATOM   10066 H HD21 . ASN B 1 322 ? -22.305 14.133  44.289 1.00 56.38 ?  288  ASN B HD21 1 
ATOM   10067 H HD22 . ASN B 1 322 ? -20.913 14.092  44.817 1.00 56.38 ?  288  ASN B HD22 1 
ATOM   10068 N N    . THR B 1 323 ? -22.846 18.528  40.035 1.00 15.45 ?  289  THR B N    1 
ATOM   10069 C CA   . THR B 1 323 ? -23.497 18.851  38.770 1.00 12.85 ?  289  THR B CA   1 
ATOM   10070 C C    . THR B 1 323 ? -22.723 19.986  38.116 1.00 14.32 ?  289  THR B C    1 
ATOM   10071 O O    . THR B 1 323 ? -21.938 20.678  38.767 1.00 19.07 ?  289  THR B O    1 
ATOM   10072 C CB   . THR B 1 323 ? -24.965 19.263  38.956 1.00 12.19 ?  289  THR B CB   1 
ATOM   10073 O OG1  . THR B 1 323 ? -25.031 20.526  39.646 1.00 13.89 ?  289  THR B OG1  1 
ATOM   10074 C CG2  . THR B 1 323 ? -25.744 18.208  39.724 1.00 15.10 ?  289  THR B CG2  1 
ATOM   10075 H H    . THR B 1 323 ? -22.572 19.220  40.467 1.00 18.53 ?  289  THR B H    1 
ATOM   10076 H HA   . THR B 1 323 ? -23.482 18.072  38.192 1.00 15.42 ?  289  THR B HA   1 
ATOM   10077 H HB   . THR B 1 323 ? -25.382 19.352  38.084 1.00 14.63 ?  289  THR B HB   1 
ATOM   10078 H HG1  . THR B 1 323 ? -24.453 20.551  40.254 1.00 16.66 ?  289  THR B HG1  1 
ATOM   10079 H HG21 . THR B 1 323 ? -26.646 18.521  39.895 1.00 18.12 ?  289  THR B HG21 1 
ATOM   10080 H HG22 . THR B 1 323 ? -25.789 17.387  39.208 1.00 18.12 ?  289  THR B HG22 1 
ATOM   10081 H HG23 . THR B 1 323 ? -25.308 18.025  40.570 1.00 18.12 ?  289  THR B HG23 1 
ATOM   10082 N N    . GLY B 1 324 ? -22.959 20.189  36.820 1.00 12.54 ?  290  GLY B N    1 
ATOM   10083 C CA   . GLY B 1 324 ? -22.412 21.321  36.106 1.00 12.68 ?  290  GLY B CA   1 
ATOM   10084 C C    . GLY B 1 324 ? -21.290 21.007  35.143 1.00 13.56 ?  290  GLY B C    1 
ATOM   10085 O O    . GLY B 1 324 ? -20.822 21.928  34.454 1.00 17.02 ?  290  GLY B O    1 
ATOM   10086 H H    . GLY B 1 324 ? -23.443 19.671  36.333 1.00 15.05 ?  290  GLY B H    1 
ATOM   10087 H HA2  . GLY B 1 324 ? -23.126 21.737  35.598 1.00 15.21 ?  290  GLY B HA2  1 
ATOM   10088 H HA3  . GLY B 1 324 ? -22.072 21.958  36.754 1.00 15.21 ?  290  GLY B HA3  1 
ATOM   10089 N N    . ILE B 1 325 ? -20.805 19.772  35.104 1.00 11.97 ?  291  ILE B N    1 
ATOM   10090 C CA   . ILE B 1 325 ? -19.715 19.413  34.190 1.00 11.39 ?  291  ILE B CA   1 
ATOM   10091 C C    . ILE B 1 325 ? -20.255 18.972  32.837 1.00 10.91 ?  291  ILE B C    1 
ATOM   10092 O O    . ILE B 1 325 ? -19.866 19.508  31.801 1.00 10.22 ?  291  ILE B O    1 
ATOM   10093 C CB   . ILE B 1 325 ? -18.836 18.314  34.814 1.00 10.63 ?  291  ILE B CB   1 
ATOM   10094 C CG1  . ILE B 1 325 ? -18.178 18.794  36.103 1.00 13.64 ?  291  ILE B CG1  1 
ATOM   10095 C CG2  . ILE B 1 325 ? -17.776 17.880  33.805 1.00 12.29 ?  291  ILE B CG2  1 
ATOM   10096 C CD1  . ILE B 1 325 ? -17.435 17.693  36.854 1.00 20.61 ?  291  ILE B CD1  1 
ATOM   10097 H H    . ILE B 1 325 ? -21.085 19.123  35.594 1.00 14.36 ?  291  ILE B H    1 
ATOM   10098 H HA   . ILE B 1 325 ? -19.162 20.199  34.056 1.00 13.66 ?  291  ILE B HA   1 
ATOM   10099 H HB   . ILE B 1 325 ? -19.403 17.560  35.038 1.00 12.75 ?  291  ILE B HB   1 
ATOM   10100 H HG12 . ILE B 1 325 ? -17.538 19.490  35.887 1.00 16.37 ?  291  ILE B HG12 1 
ATOM   10101 H HG13 . ILE B 1 325 ? -18.864 19.145  36.693 1.00 16.37 ?  291  ILE B HG13 1 
ATOM   10102 H HG21 . ILE B 1 325 ? -17.136 17.302  34.249 1.00 14.75 ?  291  ILE B HG21 1 
ATOM   10103 H HG22 . ILE B 1 325 ? -18.207 17.400  33.081 1.00 14.75 ?  291  ILE B HG22 1 
ATOM   10104 H HG23 . ILE B 1 325 ? -17.327 18.668  33.460 1.00 14.75 ?  291  ILE B HG23 1 
ATOM   10105 H HD11 . ILE B 1 325 ? -17.250 17.995  37.757 1.00 24.73 ?  291  ILE B HD11 1 
ATOM   10106 H HD12 . ILE B 1 325 ? -17.990 16.898  36.878 1.00 24.73 ?  291  ILE B HD12 1 
ATOM   10107 H HD13 . ILE B 1 325 ? -16.604 17.502  36.392 1.00 24.73 ?  291  ILE B HD13 1 
ATOM   10108 N N    . ASP B 1 326 ? -21.170 18.004  32.846 1.00 9.53  ?  292  ASP B N    1 
ATOM   10109 C CA   . ASP B 1 326 ? -21.812 17.489  31.641 1.00 9.26  ?  292  ASP B CA   1 
ATOM   10110 C C    . ASP B 1 326 ? -23.325 17.658  31.711 1.00 11.07 ?  292  ASP B C    1 
ATOM   10111 O O    . ASP B 1 326 ? -24.047 17.110  30.868 1.00 11.24 ?  292  ASP B O    1 
ATOM   10112 C CB   . ASP B 1 326 ? -21.441 16.020  31.428 1.00 8.67  ?  292  ASP B CB   1 
ATOM   10113 C CG   . ASP B 1 326 ? -19.979 15.835  31.091 1.00 8.74  ?  292  ASP B CG   1 
ATOM   10114 O OD1  . ASP B 1 326 ? -19.565 16.348  30.033 1.00 9.90  ?  292  ASP B OD1  1 
ATOM   10115 O OD2  . ASP B 1 326 ? -19.280 15.142  31.847 1.00 9.64  ?  292  ASP B OD2  1 
ATOM   10116 H H    . ASP B 1 326 ? -21.444 17.616  33.563 1.00 11.44 ?  292  ASP B H    1 
ATOM   10117 H HA   . ASP B 1 326 ? -21.491 17.976  30.865 1.00 11.11 ?  292  ASP B HA   1 
ATOM   10118 H HB2  . ASP B 1 326 ? -21.627 15.526  32.241 1.00 10.40 ?  292  ASP B HB2  1 
ATOM   10119 H HB3  . ASP B 1 326 ? -21.967 15.664  30.695 1.00 10.40 ?  292  ASP B HB3  1 
ATOM   10120 N N    . ASP B 1 327 ? -23.813 18.415  32.689 1.00 9.86  ?  293  ASP B N    1 
ATOM   10121 C CA   . ASP B 1 327 ? -25.232 18.668  32.871 1.00 11.90 ?  293  ASP B CA   1 
ATOM   10122 C C    . ASP B 1 327 ? -25.379 20.073  33.442 1.00 10.07 ?  293  ASP B C    1 
ATOM   10123 O O    . ASP B 1 327 ? -24.393 20.763  33.731 1.00 11.38 ?  293  ASP B O    1 
ATOM   10124 C CB   . ASP B 1 327 ? -25.894 17.577  33.724 1.00 10.84 ?  293  ASP B CB   1 
ATOM   10125 C CG   . ASP B 1 327 ? -25.189 17.317  35.040 1.00 11.54 ?  293  ASP B CG   1 
ATOM   10126 O OD1  . ASP B 1 327 ? -24.491 18.222  35.544 1.00 11.67 ?  293  ASP B OD1  1 
ATOM   10127 O OD2  . ASP B 1 327 ? -25.366 16.202  35.597 1.00 12.49 ?  293  ASP B OD2  1 
ATOM   10128 H H    . ASP B 1 327 ? -23.323 18.805  33.278 1.00 11.83 ?  293  ASP B H    1 
ATOM   10129 H HA   . ASP B 1 327 ? -25.699 18.657  32.021 1.00 14.28 ?  293  ASP B HA   1 
ATOM   10130 H HB2  . ASP B 1 327 ? -26.804 17.847  33.925 1.00 13.01 ?  293  ASP B HB2  1 
ATOM   10131 H HB3  . ASP B 1 327 ? -25.898 16.747  33.222 1.00 13.01 ?  293  ASP B HB3  1 
ATOM   10132 N N    . GLN B 1 328 ? -26.629 20.523  33.561 1.00 11.08 ?  294  GLN B N    1 
ATOM   10133 C CA   . GLN B 1 328 ? -26.893 21.816  34.175 1.00 11.89 ?  294  GLN B CA   1 
ATOM   10134 C C    . GLN B 1 328 ? -26.397 21.820  35.615 1.00 10.17 ?  294  GLN B C    1 
ATOM   10135 O O    . GLN B 1 328 ? -26.534 20.836  36.336 1.00 11.65 ?  294  GLN B O    1 
ATOM   10136 C CB   . GLN B 1 328 ? -28.401 22.079  34.121 1.00 14.11 ?  294  GLN B CB   1 
ATOM   10137 C CG   . GLN B 1 328 ? -28.933 23.235  34.954 1.00 19.63 ?  294  GLN B CG   1 
ATOM   10138 C CD   . GLN B 1 328 ? -30.450 23.246  34.970 1.00 26.71 ?  294  GLN B CD   1 
ATOM   10139 O OE1  . GLN B 1 328 ? -31.090 22.495  34.221 1.00 22.31 ?  294  GLN B OE1  1 
ATOM   10140 N NE2  . GLN B 1 328 ? -31.032 24.064  35.843 1.00 35.58 ?  294  GLN B NE2  1 
ATOM   10141 H H    . GLN B 1 328 ? -27.331 20.102  33.297 1.00 13.30 ?  294  GLN B H    1 
ATOM   10142 H HA   . GLN B 1 328 ? -26.433 22.527  33.702 1.00 14.27 ?  294  GLN B HA   1 
ATOM   10143 H HB2  . GLN B 1 328 ? -28.639 22.263  33.198 1.00 16.94 ?  294  GLN B HB2  1 
ATOM   10144 H HB3  . GLN B 1 328 ? -28.855 21.279  34.427 1.00 16.94 ?  294  GLN B HB3  1 
ATOM   10145 H HG2  . GLN B 1 328 ? -28.617 23.147  35.866 1.00 23.55 ?  294  GLN B HG2  1 
ATOM   10146 H HG3  . GLN B 1 328 ? -28.624 24.073  34.576 1.00 23.55 ?  294  GLN B HG3  1 
ATOM   10147 H HE21 . GLN B 1 328 ? -30.551 24.553  36.362 1.00 42.70 ?  294  GLN B HE21 1 
ATOM   10148 H HE22 . GLN B 1 328 ? -31.890 24.104  35.889 1.00 42.70 ?  294  GLN B HE22 1 
ATOM   10149 N N    . ARG B 1 329 ? -25.796 22.928  36.017 1.00 12.26 ?  295  ARG B N    1 
ATOM   10150 C CA   . ARG B 1 329 ? -25.406 23.129  37.403 1.00 11.43 ?  295  ARG B CA   1 
ATOM   10151 C C    . ARG B 1 329 ? -26.665 23.457  38.197 1.00 11.66 ?  295  ARG B C    1 
ATOM   10152 O O    . ARG B 1 329 ? -27.317 24.483  37.954 1.00 15.23 ?  295  ARG B O    1 
ATOM   10153 C CB   . ARG B 1 329 ? -24.399 24.271  37.514 1.00 13.88 ?  295  ARG B CB   1 
ATOM   10154 C CG   . ARG B 1 329 ? -23.836 24.469  38.915 1.00 15.96 ?  295  ARG B CG   1 
ATOM   10155 C CD   . ARG B 1 329 ? -22.981 25.746  39.028 1.00 20.37 ?  295  ARG B CD   1 
ATOM   10156 N NE   . ARG B 1 329 ? -22.382 25.868  40.353 1.00 24.65 ?  295  ARG B NE   1 
ATOM   10157 C CZ   . ARG B 1 329 ? -21.545 26.829  40.724 1.00 28.02 ?  295  ARG B CZ   1 
ATOM   10158 N NH1  . ARG B 1 329 ? -21.182 27.789  39.894 1.00 22.21 ?  295  ARG B NH1  1 
ATOM   10159 N NH2  . ARG B 1 329 ? -21.056 26.821  41.960 1.00 24.93 ?  295  ARG B NH2  1 
ATOM   10160 H H    . ARG B 1 329 ? -25.600 23.587  35.500 1.00 14.71 ?  295  ARG B H    1 
ATOM   10161 H HA   . ARG B 1 329 ? -24.990 22.327  37.757 1.00 13.72 ?  295  ARG B HA   1 
ATOM   10162 H HB2  . ARG B 1 329 ? -23.655 24.088  36.920 1.00 16.65 ?  295  ARG B HB2  1 
ATOM   10163 H HB3  . ARG B 1 329 ? -24.836 25.097  37.253 1.00 16.65 ?  295  ARG B HB3  1 
ATOM   10164 H HG2  . ARG B 1 329 ? -24.569 24.540  39.545 1.00 19.15 ?  295  ARG B HG2  1 
ATOM   10165 H HG3  . ARG B 1 329 ? -23.275 23.710  39.142 1.00 19.15 ?  295  ARG B HG3  1 
ATOM   10166 H HD2  . ARG B 1 329 ? -22.268 25.715  38.371 1.00 24.44 ?  295  ARG B HD2  1 
ATOM   10167 H HD3  . ARG B 1 329 ? -23.542 26.523  38.873 1.00 24.44 ?  295  ARG B HD3  1 
ATOM   10168 H HE   . ARG B 1 329 ? -22.587 25.272  40.938 1.00 29.58 ?  295  ARG B HE   1 
ATOM   10169 H HH11 . ARG B 1 329 ? -21.490 27.802  39.091 1.00 26.65 ?  295  ARG B HH11 1 
ATOM   10170 H HH12 . ARG B 1 329 ? -20.639 28.402  40.156 1.00 26.65 ?  295  ARG B HH12 1 
ATOM   10171 H HH21 . ARG B 1 329 ? -21.282 26.198  42.508 1.00 29.91 ?  295  ARG B HH21 1 
ATOM   10172 H HH22 . ARG B 1 329 ? -20.513 27.438  42.212 1.00 29.91 ?  295  ARG B HH22 1 
ATOM   10173 N N    . GLU B 1 330 ? -27.009 22.585  39.135 1.00 12.77 ?  296  GLU B N    1 
ATOM   10174 C CA   . GLU B 1 330 ? -28.223 22.779  39.924 1.00 14.25 ?  296  GLU B CA   1 
ATOM   10175 C C    . GLU B 1 330 ? -28.057 23.937  40.909 1.00 16.41 ?  296  GLU B C    1 
ATOM   10176 O O    . GLU B 1 330 ? -26.975 24.170  41.430 1.00 17.23 ?  296  GLU B O    1 
ATOM   10177 C CB   . GLU B 1 330 ? -28.523 21.499  40.697 1.00 18.36 ?  296  GLU B CB   1 
ATOM   10178 H H    . GLU B 1 330 ? -26.562 21.878  39.335 1.00 15.32 ?  296  GLU B H    1 
ATOM   10179 H HA   . GLU B 1 330 ? -28.968 22.987  39.338 1.00 17.10 ?  296  GLU B HA   1 
ATOM   10180 N N    . ASP B 1 331 ? -29.151 24.663  41.155 1.00 16.63 ?  297  ASP B N    1 
ATOM   10181 C CA   . ASP B 1 331 ? -29.145 25.761  42.113 1.00 17.87 ?  297  ASP B CA   1 
ATOM   10182 C C    . ASP B 1 331 ? -28.678 25.270  43.479 1.00 17.42 ?  297  ASP B C    1 
ATOM   10183 O O    . ASP B 1 331 ? -29.079 24.203  43.939 1.00 16.40 ?  297  ASP B O    1 
ATOM   10184 C CB   . ASP B 1 331 ? -30.577 26.286  42.322 1.00 17.11 ?  297  ASP B CB   1 
ATOM   10185 C CG   . ASP B 1 331 ? -31.081 27.183  41.212 1.00 21.50 ?  297  ASP B CG   1 
ATOM   10186 O OD1  . ASP B 1 331 ? -30.429 27.316  40.155 1.00 23.97 ?  297  ASP B OD1  1 
ATOM   10187 O OD2  . ASP B 1 331 ? -32.177 27.757  41.423 1.00 17.49 ?  297  ASP B OD2  1 
ATOM   10188 H H    . ASP B 1 331 ? -29.913 24.536  40.776 1.00 19.96 ?  297  ASP B H    1 
ATOM   10189 H HA   . ASP B 1 331 ? -28.562 26.458  41.773 1.00 21.45 ?  297  ASP B HA   1 
ATOM   10190 H HB2  . ASP B 1 331 ? -31.179 25.527  42.382 1.00 20.53 ?  297  ASP B HB2  1 
ATOM   10191 H HB3  . ASP B 1 331 ? -30.603 26.796  43.146 1.00 20.53 ?  297  ASP B HB3  1 
ATOM   10192 N N    . VAL B 1 332 ? -27.854 26.062  44.145 1.00 21.22 ?  298  VAL B N    1 
ATOM   10193 C CA   . VAL B 1 332 ? -27.590 25.854  45.564 1.00 25.50 ?  298  VAL B CA   1 
ATOM   10194 C C    . VAL B 1 332 ? -28.609 26.690  46.325 1.00 16.03 ?  298  VAL B C    1 
ATOM   10195 O O    . VAL B 1 332 ? -28.816 27.866  46.016 1.00 18.99 ?  298  VAL B O    1 
ATOM   10196 C CB   . VAL B 1 332 ? -26.145 26.242  45.931 1.00 26.52 ?  298  VAL B CB   1 
ATOM   10197 C CG1  . VAL B 1 332 ? -25.814 27.656  45.454 1.00 33.13 ?  298  VAL B CG1  1 
ATOM   10198 C CG2  . VAL B 1 332 ? -25.916 26.067  47.434 1.00 35.04 ?  298  VAL B CG2  1 
ATOM   10199 H H    . VAL B 1 332 ? -27.433 26.728  43.799 1.00 25.46 ?  298  VAL B H    1 
ATOM   10200 H HA   . VAL B 1 332 ? -27.698 24.919  45.798 1.00 30.60 ?  298  VAL B HA   1 
ATOM   10201 H HB   . VAL B 1 332 ? -25.529 25.649  45.473 1.00 31.83 ?  298  VAL B HB   1 
ATOM   10202 H HG11 . VAL B 1 332 ? -24.918 27.886  45.746 1.00 39.76 ?  298  VAL B HG11 1 
ATOM   10203 H HG12 . VAL B 1 332 ? -25.863 27.682  44.485 1.00 39.76 ?  298  VAL B HG12 1 
ATOM   10204 H HG13 . VAL B 1 332 ? -26.456 28.276  45.834 1.00 39.76 ?  298  VAL B HG13 1 
ATOM   10205 H HG21 . VAL B 1 332 ? -24.999 26.304  47.643 1.00 42.05 ?  298  VAL B HG21 1 
ATOM   10206 H HG22 . VAL B 1 332 ? -26.526 26.648  47.916 1.00 42.05 ?  298  VAL B HG22 1 
ATOM   10207 H HG23 . VAL B 1 332 ? -26.082 25.142  47.673 1.00 42.05 ?  298  VAL B HG23 1 
ATOM   10208 N N    . ASP B 1 333 ? -29.330 26.056  47.247 1.00 15.08 ?  299  ASP B N    1 
ATOM   10209 C CA   . ASP B 1 333 ? -30.287 26.800  48.054 1.00 13.70 ?  299  ASP B CA   1 
ATOM   10210 C C    . ASP B 1 333 ? -29.500 27.683  49.011 1.00 15.53 ?  299  ASP B C    1 
ATOM   10211 O O    . ASP B 1 333 ? -28.925 27.193  49.988 1.00 15.78 ?  299  ASP B O    1 
ATOM   10212 C CB   . ASP B 1 333 ? -31.189 25.835  48.808 1.00 13.22 ?  299  ASP B CB   1 
ATOM   10213 C CG   . ASP B 1 333 ? -32.205 26.528  49.686 1.00 18.44 ?  299  ASP B CG   1 
ATOM   10214 O OD1  . ASP B 1 333 ? -32.289 27.778  49.697 1.00 17.77 ?  299  ASP B OD1  1 
ATOM   10215 O OD2  . ASP B 1 333 ? -32.940 25.782  50.369 1.00 23.42 ?  299  ASP B OD2  1 
ATOM   10216 H H    . ASP B 1 333 ? -29.283 25.214  47.418 1.00 18.09 ?  299  ASP B H    1 
ATOM   10217 H HA   . ASP B 1 333 ? -30.851 27.356  47.494 1.00 16.44 ?  299  ASP B HA   1 
ATOM   10218 H HB2  . ASP B 1 333 ? -31.672 25.291  48.166 1.00 15.86 ?  299  ASP B HB2  1 
ATOM   10219 H HB3  . ASP B 1 333 ? -30.641 25.271  49.375 1.00 15.86 ?  299  ASP B HB3  1 
ATOM   10220 N N    . LEU B 1 334 ? -29.465 28.977  48.729 1.00 12.77 ?  300  LEU B N    1 
ATOM   10221 C CA   . LEU B 1 334 ? -28.682 29.894  49.548 1.00 12.07 ?  300  LEU B CA   1 
ATOM   10222 C C    . LEU B 1 334 ? -29.280 30.085  50.932 1.00 16.89 ?  300  LEU B C    1 
ATOM   10223 O O    . LEU B 1 334 ? -28.614 30.662  51.797 1.00 17.69 ?  300  LEU B O    1 
ATOM   10224 C CB   . LEU B 1 334 ? -28.525 31.221  48.810 1.00 15.73 ?  300  LEU B CB   1 
ATOM   10225 C CG   . LEU B 1 334 ? -27.685 31.118  47.532 1.00 15.83 ?  300  LEU B CG   1 
ATOM   10226 C CD1  . LEU B 1 334 ? -27.699 32.434  46.777 1.00 18.50 ?  300  LEU B CD1  1 
ATOM   10227 C CD2  . LEU B 1 334 ? -26.232 30.713  47.819 1.00 17.97 ?  300  LEU B CD2  1 
ATOM   10228 H H    . LEU B 1 334 ? -29.882 29.347  48.074 1.00 15.32 ?  300  LEU B H    1 
ATOM   10229 H HA   . LEU B 1 334 ? -27.788 29.541  49.683 1.00 14.49 ?  300  LEU B HA   1 
ATOM   10230 H HB2  . LEU B 1 334 ? -29.404 31.546  48.562 1.00 18.88 ?  300  LEU B HB2  1 
ATOM   10231 H HB3  . LEU B 1 334 ? -28.090 31.856  49.401 1.00 18.88 ?  300  LEU B HB3  1 
ATOM   10232 H HG   . LEU B 1 334 ? -28.081 30.424  46.982 1.00 18.99 ?  300  LEU B HG   1 
ATOM   10233 H HD11 . LEU B 1 334 ? -27.328 32.294  45.892 1.00 22.21 ?  300  LEU B HD11 1 
ATOM   10234 H HD12 . LEU B 1 334 ? -28.615 32.747  46.707 1.00 22.21 ?  300  LEU B HD12 1 
ATOM   10235 H HD13 . LEU B 1 334 ? -27.164 33.082  47.262 1.00 22.21 ?  300  LEU B HD13 1 
ATOM   10236 H HD21 . LEU B 1 334 ? -25.705 30.836  47.014 1.00 21.56 ?  300  LEU B HD21 1 
ATOM   10237 H HD22 . LEU B 1 334 ? -25.883 31.273  48.531 1.00 21.56 ?  300  LEU B HD22 1 
ATOM   10238 H HD23 . LEU B 1 334 ? -26.212 29.782  48.090 1.00 21.56 ?  300  LEU B HD23 1 
ATOM   10239 N N    . ASN B 1 335 ? -30.513 29.634  51.156 1.00 14.29 ?  301  ASN B N    1 
ATOM   10240 C CA   . ASN B 1 335 ? -31.136 29.696  52.476 1.00 17.09 ?  301  ASN B CA   1 
ATOM   10241 C C    . ASN B 1 335 ? -31.058 28.364  53.209 1.00 15.09 ?  301  ASN B C    1 
ATOM   10242 O O    . ASN B 1 335 ? -31.650 28.228  54.287 1.00 21.37 ?  301  ASN B O    1 
ATOM   10243 C CB   . ASN B 1 335 ? -32.601 30.167  52.395 1.00 17.62 ?  301  ASN B CB   1 
ATOM   10244 C CG   . ASN B 1 335 ? -32.728 31.619  51.976 1.00 23.84 ?  301  ASN B CG   1 
ATOM   10245 O OD1  . ASN B 1 335 ? -32.383 32.526  52.733 1.00 25.86 ?  301  ASN B OD1  1 
ATOM   10246 N ND2  . ASN B 1 335 ? -33.291 31.850  50.788 1.00 27.10 ?  301  ASN B ND2  1 
ATOM   10247 H H    . ASN B 1 335 ? -31.015 29.284  50.552 1.00 17.14 ?  301  ASN B H    1 
ATOM   10248 H HA   . ASN B 1 335 ? -30.661 30.363  52.994 1.00 20.51 ?  301  ASN B HA   1 
ATOM   10249 H HB2  . ASN B 1 335 ? -33.071 29.625  51.743 1.00 21.15 ?  301  ASN B HB2  1 
ATOM   10250 H HB3  . ASN B 1 335 ? -33.013 30.069  53.267 1.00 21.15 ?  301  ASN B HB3  1 
ATOM   10251 H HD21 . ASN B 1 335 ? -33.559 31.192  50.304 1.00 32.52 ?  301  ASN B HD21 1 
ATOM   10252 H HD22 . ASN B 1 335 ? -33.385 32.657  50.507 1.00 32.52 ?  301  ASN B HD22 1 
ATOM   10253 N N    . ASP B 1 336 ? -30.344 27.387  52.658 1.00 13.30 ?  302  ASP B N    1 
ATOM   10254 C CA   . ASP B 1 336 ? -30.295 26.054  53.244 1.00 19.34 ?  302  ASP B CA   1 
ATOM   10255 C C    . ASP B 1 336 ? -29.713 26.108  54.650 1.00 19.78 ?  302  ASP B C    1 
ATOM   10256 O O    . ASP B 1 336 ? -28.797 26.884  54.933 1.00 17.58 ?  302  ASP B O    1 
ATOM   10257 C CB   . ASP B 1 336 ? -29.412 25.169  52.361 1.00 20.40 ?  302  ASP B CB   1 
ATOM   10258 C CG   . ASP B 1 336 ? -29.233 23.783  52.905 1.00 31.12 ?  302  ASP B CG   1 
ATOM   10259 O OD1  . ASP B 1 336 ? -30.167 22.968  52.776 1.00 31.20 ?  302  ASP B OD1  1 
ATOM   10260 O OD2  . ASP B 1 336 ? -28.139 23.497  53.437 1.00 26.20 ?  302  ASP B OD2  1 
ATOM   10261 H H    . ASP B 1 336 ? -29.877 27.471  51.940 1.00 15.96 ?  302  ASP B H    1 
ATOM   10262 H HA   . ASP B 1 336 ? -31.187 25.680  53.300 1.00 23.21 ?  302  ASP B HA   1 
ATOM   10263 H HB2  . ASP B 1 336 ? -29.820 25.094  51.484 1.00 24.48 ?  302  ASP B HB2  1 
ATOM   10264 H HB3  . ASP B 1 336 ? -28.535 25.575  52.285 1.00 24.48 ?  302  ASP B HB3  1 
ATOM   10265 N N    . GLU B 1 337 ? -30.233 25.257  55.535 1.00 19.98 ?  303  GLU B N    1 
ATOM   10266 C CA   . GLU B 1 337 ? -29.742 25.236  56.913 1.00 20.88 ?  303  GLU B CA   1 
ATOM   10267 C C    . GLU B 1 337 ? -28.277 24.811  56.986 1.00 18.71 ?  303  GLU B C    1 
ATOM   10268 O O    . GLU B 1 337 ? -27.490 25.398  57.743 1.00 16.65 ?  303  GLU B O    1 
ATOM   10269 C CB   . GLU B 1 337 ? -30.615 24.304  57.760 1.00 24.52 ?  303  GLU B CB   1 
ATOM   10270 H H    . GLU B 1 337 ? -30.859 24.692  55.367 1.00 23.97 ?  303  GLU B H    1 
ATOM   10271 H HA   . GLU B 1 337 ? -29.804 26.133  57.277 1.00 25.06 ?  303  GLU B HA   1 
ATOM   10272 H HB2  . GLU B 1 337 ? -31.234 24.842  58.280 1.00 29.42 ?  303  GLU B HB2  1 
ATOM   10273 H HB3  . GLU B 1 337 ? -31.108 23.709  57.175 1.00 29.42 ?  303  GLU B HB3  1 
ATOM   10274 N N    . GLU B 1 338 ? -27.879 23.803  56.212 1.00 20.48 ?  304  GLU B N    1 
ATOM   10275 C CA   . GLU B 1 338 ? -26.495 23.338  56.284 1.00 18.74 ?  304  GLU B CA   1 
ATOM   10276 C C    . GLU B 1 338 ? -25.527 24.376  55.722 1.00 19.95 ?  304  GLU B C    1 
ATOM   10277 O O    . GLU B 1 338 ? -24.446 24.607  56.281 1.00 20.26 ?  304  GLU B O    1 
ATOM   10278 C CB   . GLU B 1 338 ? -26.329 22.004  55.559 1.00 28.43 ?  304  GLU B CB   1 
ATOM   10279 C CG   . GLU B 1 338 ? -26.717 20.787  56.392 1.00 36.81 ?  304  GLU B CG   1 
ATOM   10280 C CD   . GLU B 1 338 ? -25.923 20.672  57.680 1.00 42.97 ?  304  GLU B CD   1 
ATOM   10281 O OE1  . GLU B 1 338 ? -26.545 20.483  58.750 1.00 45.17 ?  304  GLU B OE1  1 
ATOM   10282 O OE2  . GLU B 1 338 ? -24.678 20.765  57.617 1.00 44.65 ?  304  GLU B OE2  1 
ATOM   10283 H H    . GLU B 1 338 ? -28.376 23.382  55.651 1.00 24.58 ?  304  GLU B H    1 
ATOM   10284 H HA   . GLU B 1 338 ? -26.276 23.193  57.218 1.00 22.49 ?  304  GLU B HA   1 
ATOM   10285 H HB2  . GLU B 1 338 ? -26.888 22.009  54.767 1.00 34.11 ?  304  GLU B HB2  1 
ATOM   10286 H HB3  . GLU B 1 338 ? -25.398 21.902  55.307 1.00 34.11 ?  304  GLU B HB3  1 
ATOM   10287 H HG2  . GLU B 1 338 ? -27.657 20.852  56.625 1.00 44.17 ?  304  GLU B HG2  1 
ATOM   10288 H HG3  . GLU B 1 338 ? -26.560 19.985  55.870 1.00 44.17 ?  304  GLU B HG3  1 
ATOM   10289 N N    . LEU B 1 339 ? -25.879 25.011  54.610 1.00 16.45 ?  305  LEU B N    1 
ATOM   10290 C CA   . LEU B 1 339 ? -24.988 26.034  54.087 1.00 15.62 ?  305  LEU B CA   1 
ATOM   10291 C C    . LEU B 1 339 ? -24.851 27.161  55.092 1.00 14.16 ?  305  LEU B C    1 
ATOM   10292 O O    . LEU B 1 339 ? -23.759 27.714  55.266 1.00 14.15 ?  305  LEU B O    1 
ATOM   10293 C CB   . LEU B 1 339 ? -25.491 26.561  52.745 1.00 17.47 ?  305  LEU B CB   1 
ATOM   10294 C CG   . LEU B 1 339 ? -24.707 27.719  52.125 1.00 15.35 ?  305  LEU B CG   1 
ATOM   10295 C CD1  . LEU B 1 339 ? -23.282 27.296  51.850 1.00 18.72 ?  305  LEU B CD1  1 
ATOM   10296 C CD2  . LEU B 1 339 ? -25.378 28.184  50.832 1.00 17.20 ?  305  LEU B CD2  1 
ATOM   10297 H H    . LEU B 1 339 ? -26.598 24.874  54.158 1.00 19.74 ?  305  LEU B H    1 
ATOM   10298 H HA   . LEU B 1 339 ? -24.114 25.645  53.925 1.00 18.74 ?  305  LEU B HA   1 
ATOM   10299 H HB2  . LEU B 1 339 ? -25.469 25.830  52.108 1.00 20.97 ?  305  LEU B HB2  1 
ATOM   10300 H HB3  . LEU B 1 339 ? -26.404 26.867  52.866 1.00 20.97 ?  305  LEU B HB3  1 
ATOM   10301 H HG   . LEU B 1 339 ? -24.694 28.464  52.747 1.00 18.42 ?  305  LEU B HG   1 
ATOM   10302 H HD11 . LEU B 1 339 ? -22.810 28.031  51.428 1.00 22.47 ?  305  LEU B HD11 1 
ATOM   10303 H HD12 . LEU B 1 339 ? -22.853 27.066  52.689 1.00 22.47 ?  305  LEU B HD12 1 
ATOM   10304 H HD13 . LEU B 1 339 ? -23.289 26.526  51.260 1.00 22.47 ?  305  LEU B HD13 1 
ATOM   10305 H HD21 . LEU B 1 339 ? -24.899 28.954  50.487 1.00 20.65 ?  305  LEU B HD21 1 
ATOM   10306 H HD22 . LEU B 1 339 ? -25.351 27.461  50.185 1.00 20.65 ?  305  LEU B HD22 1 
ATOM   10307 H HD23 . LEU B 1 339 ? -26.298 28.424  51.022 1.00 20.65 ?  305  LEU B HD23 1 
ATOM   10308 N N    . ASN B 1 340 ? -25.939 27.506  55.773 1.00 13.81 ?  306  ASN B N    1 
ATOM   10309 C CA   . ASN B 1 340 ? -25.884 28.613  56.713 1.00 13.98 ?  306  ASN B CA   1 
ATOM   10310 C C    . ASN B 1 340 ? -25.083 28.271  57.958 1.00 13.97 ?  306  ASN B C    1 
ATOM   10311 O O    . ASN B 1 340 ? -24.448 29.162  58.528 1.00 12.51 ?  306  ASN B O    1 
ATOM   10312 C CB   . ASN B 1 340 ? -27.280 29.127  57.011 1.00 14.93 ?  306  ASN B CB   1 
ATOM   10313 C CG   . ASN B 1 340 ? -27.712 30.172  56.009 1.00 19.16 ?  306  ASN B CG   1 
ATOM   10314 O OD1  . ASN B 1 340 ? -27.502 31.363  56.220 1.00 17.72 ?  306  ASN B OD1  1 
ATOM   10315 N ND2  . ASN B 1 340 ? -28.253 29.726  54.870 1.00 21.90 ?  306  ASN B ND2  1 
ATOM   10316 H H    . ASN B 1 340 ? -26.705 27.122  55.709 1.00 16.57 ?  306  ASN B H    1 
ATOM   10317 H HA   . ASN B 1 340 ? -25.416 29.358  56.304 1.00 16.78 ?  306  ASN B HA   1 
ATOM   10318 H HB2  . ASN B 1 340 ? -27.909 28.389  56.971 1.00 17.91 ?  306  ASN B HB2  1 
ATOM   10319 H HB3  . ASN B 1 340 ? -27.293 29.527  57.894 1.00 17.91 ?  306  ASN B HB3  1 
ATOM   10320 H HD21 . ASN B 1 340 ? -28.514 30.284  54.270 1.00 26.28 ?  306  ASN B HD21 1 
ATOM   10321 H HD22 . ASN B 1 340 ? -28.340 28.880  54.738 1.00 26.28 ?  306  ASN B HD22 1 
ATOM   10322 N N    . LYS B 1 341 ? -25.063 27.005  58.365 1.00 13.94 ?  307  LYS B N    1 
ATOM   10323 C CA   . LYS B 1 341 ? -24.153 26.593  59.431 1.00 13.69 ?  307  LYS B CA   1 
ATOM   10324 C C    . LYS B 1 341 ? -22.703 26.745  59.005 1.00 14.88 ?  307  LYS B C    1 
ATOM   10325 O O    . LYS B 1 341 ? -21.848 27.121  59.817 1.00 13.52 ?  307  LYS B O    1 
ATOM   10326 C CB   . LYS B 1 341 ? -24.427 25.152  59.845 1.00 19.33 ?  307  LYS B CB   1 
ATOM   10327 C CG   . LYS B 1 341 ? -25.770 24.942  60.496 1.00 27.05 ?  307  LYS B CG   1 
ATOM   10328 C CD   . LYS B 1 341 ? -25.975 23.464  60.819 1.00 32.83 ?  307  LYS B CD   1 
ATOM   10329 C CE   . LYS B 1 341 ? -27.250 23.229  61.609 1.00 40.78 ?  307  LYS B CE   1 
ATOM   10330 N NZ   . LYS B 1 341 ? -27.660 21.794  61.571 1.00 44.87 ?  307  LYS B NZ   1 
ATOM   10331 H H    . LYS B 1 341 ? -25.557 26.376  58.048 1.00 16.73 ?  307  LYS B H    1 
ATOM   10332 H HA   . LYS B 1 341 ? -24.310 27.161  60.202 1.00 16.43 ?  307  LYS B HA   1 
ATOM   10333 H HB2  . LYS B 1 341 ? -24.391 24.590  59.054 1.00 23.20 ?  307  LYS B HB2  1 
ATOM   10334 H HB3  . LYS B 1 341 ? -23.746 24.876  60.478 1.00 23.20 ?  307  LYS B HB3  1 
ATOM   10335 H HG2  . LYS B 1 341 ? -25.815 25.449  61.322 1.00 32.46 ?  307  LYS B HG2  1 
ATOM   10336 H HG3  . LYS B 1 341 ? -26.474 25.228  59.892 1.00 32.46 ?  307  LYS B HG3  1 
ATOM   10337 H HD2  . LYS B 1 341 ? -26.033 22.961  59.992 1.00 39.39 ?  307  LYS B HD2  1 
ATOM   10338 H HD3  . LYS B 1 341 ? -25.227 23.146  61.349 1.00 39.39 ?  307  LYS B HD3  1 
ATOM   10339 H HE2  . LYS B 1 341 ? -27.106 23.480  62.535 1.00 48.94 ?  307  LYS B HE2  1 
ATOM   10340 H HE3  . LYS B 1 341 ? -27.966 23.761  61.229 1.00 48.94 ?  307  LYS B HE3  1 
ATOM   10341 H HZ1  . LYS B 1 341 ? -28.412 21.680  62.033 1.00 53.85 ?  307  LYS B HZ1  1 
ATOM   10342 H HZ2  . LYS B 1 341 ? -27.798 21.539  60.729 1.00 53.85 ?  307  LYS B HZ2  1 
ATOM   10343 H HZ3  . LYS B 1 341 ? -27.022 21.286  61.926 1.00 53.85 ?  307  LYS B HZ3  1 
ATOM   10344 N N    . ARG B 1 342 ? -22.395 26.456  57.738 1.00 12.99 ?  308  ARG B N    1 
ATOM   10345 C CA   . ARG B 1 342 ? -21.042 26.653  57.226 1.00 13.55 ?  308  ARG B CA   1 
ATOM   10346 C C    . ARG B 1 342 ? -20.664 28.126  57.212 1.00 11.12 ?  308  ARG B C    1 
ATOM   10347 O O    . ARG B 1 342 ? -19.538 28.498  57.582 1.00 11.63 ?  308  ARG B O    1 
ATOM   10348 C CB   . ARG B 1 342 ? -20.928 26.073  55.812 1.00 13.87 ?  308  ARG B CB   1 
ATOM   10349 C CG   . ARG B 1 342 ? -19.526 25.950  55.270 1.00 16.69 ?  308  ARG B CG   1 
ATOM   10350 C CD   . ARG B 1 342 ? -18.597 25.272  56.257 1.00 23.25 ?  308  ARG B CD   1 
ATOM   10351 N NE   . ARG B 1 342 ? -17.209 25.245  55.824 1.00 27.73 ?  308  ARG B NE   1 
ATOM   10352 C CZ   . ARG B 1 342 ? -16.253 24.579  56.457 1.00 19.00 ?  308  ARG B CZ   1 
ATOM   10353 N NH1  . ARG B 1 342 ? -16.510 23.870  57.546 1.00 21.98 ?  308  ARG B NH1  1 
ATOM   10354 N NH2  . ARG B 1 342 ? -15.020 24.618  55.980 1.00 19.98 ?  308  ARG B NH2  1 
ATOM   10355 H H    . ARG B 1 342 ? -22.950 26.146  57.158 1.00 15.59 ?  308  ARG B H    1 
ATOM   10356 H HA   . ARG B 1 342 ? -20.421 26.184  57.805 1.00 16.26 ?  308  ARG B HA   1 
ATOM   10357 H HB2  . ARG B 1 342 ? -21.315 25.183  55.816 1.00 16.64 ?  308  ARG B HB2  1 
ATOM   10358 H HB3  . ARG B 1 342 ? -21.423 26.647  55.206 1.00 16.64 ?  308  ARG B HB3  1 
ATOM   10359 H HG2  . ARG B 1 342 ? -19.542 25.422  54.456 1.00 20.03 ?  308  ARG B HG2  1 
ATOM   10360 H HG3  . ARG B 1 342 ? -19.176 26.836  55.083 1.00 20.03 ?  308  ARG B HG3  1 
ATOM   10361 H HD2  . ARG B 1 342 ? -18.635 25.749  57.101 1.00 27.90 ?  308  ARG B HD2  1 
ATOM   10362 H HD3  . ARG B 1 342 ? -18.887 24.355  56.381 1.00 27.90 ?  308  ARG B HD3  1 
ATOM   10363 H HE   . ARG B 1 342 ? -16.997 25.686  55.117 1.00 33.28 ?  308  ARG B HE   1 
ATOM   10364 H HH11 . ARG B 1 342 ? -17.311 23.834  57.857 1.00 26.37 ?  308  ARG B HH11 1 
ATOM   10365 H HH12 . ARG B 1 342 ? -15.875 23.445  57.942 1.00 26.37 ?  308  ARG B HH12 1 
ATOM   10366 H HH21 . ARG B 1 342 ? -14.849 25.070  55.269 1.00 23.97 ?  308  ARG B HH21 1 
ATOM   10367 H HH22 . ARG B 1 342 ? -14.390 24.191  56.380 1.00 23.97 ?  308  ARG B HH22 1 
ATOM   10368 N N    . VAL B 1 343 ? -21.581 28.982  56.758 1.00 10.56 ?  309  VAL B N    1 
ATOM   10369 C CA   . VAL B 1 343 ? -21.344 30.413  56.795 1.00 9.38  ?  309  VAL B CA   1 
ATOM   10370 C C    . VAL B 1 343 ? -21.079 30.861  58.223 1.00 10.64 ?  309  VAL B C    1 
ATOM   10371 O O    . VAL B 1 343 ? -20.145 31.622  58.478 1.00 9.88  ?  309  VAL B O    1 
ATOM   10372 C CB   . VAL B 1 343 ? -22.528 31.163  56.156 1.00 10.11 ?  309  VAL B CB   1 
ATOM   10373 C CG1  . VAL B 1 343 ? -22.450 32.637  56.420 1.00 11.38 ?  309  VAL B CG1  1 
ATOM   10374 C CG2  . VAL B 1 343 ? -22.572 30.863  54.660 1.00 11.83 ?  309  VAL B CG2  1 
ATOM   10375 H H    . VAL B 1 343 ? -22.341 28.756  56.426 1.00 12.67 ?  309  VAL B H    1 
ATOM   10376 H HA   . VAL B 1 343 ? -20.553 30.619  56.273 1.00 11.26 ?  309  VAL B HA   1 
ATOM   10377 H HB   . VAL B 1 343 ? -23.356 30.856  56.557 1.00 12.13 ?  309  VAL B HB   1 
ATOM   10378 H HG11 . VAL B 1 343 ? -23.088 33.094  55.851 1.00 13.66 ?  309  VAL B HG11 1 
ATOM   10379 H HG12 . VAL B 1 343 ? -22.659 32.802  57.352 1.00 13.66 ?  309  VAL B HG12 1 
ATOM   10380 H HG13 . VAL B 1 343 ? -21.551 32.946  56.223 1.00 13.66 ?  309  VAL B HG13 1 
ATOM   10381 H HG21 . VAL B 1 343 ? -23.376 31.253  54.283 1.00 14.19 ?  309  VAL B HG21 1 
ATOM   10382 H HG22 . VAL B 1 343 ? -21.788 31.247  54.238 1.00 14.19 ?  309  VAL B HG22 1 
ATOM   10383 H HG23 . VAL B 1 343 ? -22.579 29.902  54.531 1.00 14.19 ?  309  VAL B HG23 1 
ATOM   10384 N N    . ASP B 1 344 ? -21.882 30.374  59.178 1.00 10.01 ?  310  ASP B N    1 
ATOM   10385 C CA   . ASP B 1 344 ? -21.677 30.734  60.578 1.00 8.76  ?  310  ASP B CA   1 
ATOM   10386 C C    . ASP B 1 344 ? -20.271 30.368  61.026 1.00 10.59 ?  310  ASP B C    1 
ATOM   10387 O O    . ASP B 1 344 ? -19.611 31.154  61.712 1.00 10.20 ?  310  ASP B O    1 
ATOM   10388 C CB   . ASP B 1 344 ? -22.689 30.000  61.460 1.00 10.00 ?  310  ASP B CB   1 
ATOM   10389 C CG   . ASP B 1 344 ? -24.108 30.531  61.349 1.00 11.48 ?  310  ASP B CG   1 
ATOM   10390 O OD1  . ASP B 1 344 ? -24.339 31.622  60.790 1.00 11.67 ?  310  ASP B OD1  1 
ATOM   10391 O OD2  . ASP B 1 344 ? -24.999 29.830  61.883 1.00 12.91 ?  310  ASP B OD2  1 
ATOM   10392 H H    . ASP B 1 344 ? -22.542 29.841  59.041 1.00 12.02 ?  310  ASP B H    1 
ATOM   10393 H HA   . ASP B 1 344 ? -21.809 31.690  60.676 1.00 10.51 ?  310  ASP B HA   1 
ATOM   10394 H HB2  . ASP B 1 344 ? -22.704 29.064  61.204 1.00 12.00 ?  310  ASP B HB2  1 
ATOM   10395 H HB3  . ASP B 1 344 ? -22.414 30.086  62.387 1.00 12.00 ?  310  ASP B HB3  1 
ATOM   10396 N N    . TYR B 1 345 ? -19.812 29.167  60.668 1.00 9.47  ?  311  TYR B N    1 
ATOM   10397 C CA   . TYR B 1 345 ? -18.495 28.702  61.090 1.00 9.50  ?  311  TYR B CA   1 
ATOM   10398 C C    . TYR B 1 345 ? -17.394 29.596  60.530 1.00 10.20 ?  311  TYR B C    1 
ATOM   10399 O O    . TYR B 1 345 ? -16.498 30.032  61.262 1.00 9.61  ?  311  TYR B O    1 
ATOM   10400 C CB   . TYR B 1 345 ? -18.293 27.254  60.642 1.00 10.71 ?  311  TYR B CB   1 
ATOM   10401 C CG   . TYR B 1 345 ? -16.905 26.723  60.891 1.00 11.12 ?  311  TYR B CG   1 
ATOM   10402 C CD1  . TYR B 1 345 ? -16.438 26.570  62.187 1.00 12.22 ?  311  TYR B CD1  1 
ATOM   10403 C CD2  . TYR B 1 345 ? -16.065 26.376  59.852 1.00 12.03 ?  311  TYR B CD2  1 
ATOM   10404 C CE1  . TYR B 1 345 ? -15.180 26.095  62.429 1.00 12.13 ?  311  TYR B CE1  1 
ATOM   10405 C CE2  . TYR B 1 345 ? -14.789 25.899  60.105 1.00 11.97 ?  311  TYR B CE2  1 
ATOM   10406 C CZ   . TYR B 1 345 ? -14.378 25.753  61.403 1.00 11.95 ?  311  TYR B CZ   1 
ATOM   10407 O OH   . TYR B 1 345 ? -13.110 25.274  61.696 1.00 15.02 ?  311  TYR B OH   1 
ATOM   10408 H H    . TYR B 1 345 ? -20.244 28.605  60.182 1.00 11.36 ?  311  TYR B H    1 
ATOM   10409 H HA   . TYR B 1 345 ? -18.444 28.732  62.058 1.00 11.40 ?  311  TYR B HA   1 
ATOM   10410 H HB2  . TYR B 1 345 ? -18.916 26.690  61.125 1.00 12.85 ?  311  TYR B HB2  1 
ATOM   10411 H HB3  . TYR B 1 345 ? -18.464 27.197  59.689 1.00 12.85 ?  311  TYR B HB3  1 
ATOM   10412 H HD1  . TYR B 1 345 ? -16.989 26.793  62.903 1.00 14.66 ?  311  TYR B HD1  1 
ATOM   10413 H HD2  . TYR B 1 345 ? -16.358 26.463  58.973 1.00 14.44 ?  311  TYR B HD2  1 
ATOM   10414 H HE1  . TYR B 1 345 ? -14.877 26.009  63.304 1.00 14.55 ?  311  TYR B HE1  1 
ATOM   10415 H HE2  . TYR B 1 345 ? -14.220 25.680  59.402 1.00 14.37 ?  311  TYR B HE2  1 
ATOM   10416 H HH   . TYR B 1 345 ? -12.712 25.064  60.987 1.00 18.03 ?  311  TYR B HH   1 
ATOM   10417 N N    . LEU B 1 346 ? -17.445 29.882  59.221 1.00 9.29  ?  312  LEU B N    1 
ATOM   10418 C CA   . LEU B 1 346 ? -16.394 30.674  58.592 1.00 9.92  ?  312  LEU B CA   1 
ATOM   10419 C C    . LEU B 1 346 ? -16.407 32.105  59.108 1.00 9.11  ?  312  LEU B C    1 
ATOM   10420 O O    . LEU B 1 346 ? -15.351 32.688  59.368 1.00 8.93  ?  312  LEU B O    1 
ATOM   10421 C CB   . LEU B 1 346 ? -16.539 30.611  57.069 1.00 9.77  ?  312  LEU B CB   1 
ATOM   10422 C CG   . LEU B 1 346 ? -16.381 29.218  56.468 1.00 10.23 ?  312  LEU B CG   1 
ATOM   10423 C CD1  . LEU B 1 346 ? -16.655 29.249  54.965 1.00 12.91 ?  312  LEU B CD1  1 
ATOM   10424 C CD2  . LEU B 1 346 ? -15.014 28.611  56.735 1.00 10.23 ?  312  LEU B CD2  1 
ATOM   10425 H H    . LEU B 1 346 ? -18.070 29.632  58.687 1.00 11.15 ?  312  LEU B H    1 
ATOM   10426 H HA   . LEU B 1 346 ? -15.527 30.300  58.812 1.00 11.90 ?  312  LEU B HA   1 
ATOM   10427 H HB2  . LEU B 1 346 ? -17.422 30.934  56.831 1.00 11.72 ?  312  LEU B HB2  1 
ATOM   10428 H HB3  . LEU B 1 346 ? -15.860 31.180  56.672 1.00 11.72 ?  312  LEU B HB3  1 
ATOM   10429 H HG   . LEU B 1 346 ? -17.031 28.643  56.901 1.00 12.28 ?  312  LEU B HG   1 
ATOM   10430 H HD11 . LEU B 1 346 ? -16.693 28.339  54.632 1.00 15.49 ?  312  LEU B HD11 1 
ATOM   10431 H HD12 . LEU B 1 346 ? -17.502 29.695  54.808 1.00 15.49 ?  312  LEU B HD12 1 
ATOM   10432 H HD13 . LEU B 1 346 ? -15.939 29.734  54.524 1.00 15.49 ?  312  LEU B HD13 1 
ATOM   10433 H HD21 . LEU B 1 346 ? -14.942 27.772  56.254 1.00 12.28 ?  312  LEU B HD21 1 
ATOM   10434 H HD22 . LEU B 1 346 ? -14.330 29.228  56.430 1.00 12.28 ?  312  LEU B HD22 1 
ATOM   10435 H HD23 . LEU B 1 346 ? -14.919 28.456  57.688 1.00 12.28 ?  312  LEU B HD23 1 
ATOM   10436 N N    . LEU B 1 347 ? -17.595 32.679  59.299 1.00 8.64  ?  313  LEU B N    1 
ATOM   10437 C CA   . LEU B 1 347 ? -17.651 34.006  59.880 1.00 9.56  ?  313  LEU B CA   1 
ATOM   10438 C C    . LEU B 1 347 ? -17.157 34.013  61.319 1.00 8.85  ?  313  LEU B C    1 
ATOM   10439 O O    . LEU B 1 347 ? -16.568 35.001  61.758 1.00 9.35  ?  313  LEU B O    1 
ATOM   10440 C CB   . LEU B 1 347 ? -19.071 34.559  59.836 1.00 9.44  ?  313  LEU B CB   1 
ATOM   10441 C CG   . LEU B 1 347 ? -19.605 34.885  58.441 1.00 10.14 ?  313  LEU B CG   1 
ATOM   10442 C CD1  . LEU B 1 347 ? -21.048 35.355  58.596 1.00 11.09 ?  313  LEU B CD1  1 
ATOM   10443 C CD2  . LEU B 1 347 ? -18.743 35.930  57.756 1.00 10.63 ?  313  LEU B CD2  1 
ATOM   10444 H H    . LEU B 1 347 ? -18.356 32.329  59.104 1.00 10.37 ?  313  LEU B H    1 
ATOM   10445 H HA   . LEU B 1 347 ? -17.083 34.584  59.348 1.00 11.47 ?  313  LEU B HA   1 
ATOM   10446 H HB2  . LEU B 1 347 ? -19.667 33.901  60.228 1.00 11.33 ?  313  LEU B HB2  1 
ATOM   10447 H HB3  . LEU B 1 347 ? -19.095 35.378  60.354 1.00 11.33 ?  313  LEU B HB3  1 
ATOM   10448 H HG   . LEU B 1 347 ? -19.580 34.103  57.868 1.00 12.17 ?  313  LEU B HG   1 
ATOM   10449 H HD11 . LEU B 1 347 ? -21.416 35.539  57.718 1.00 13.31 ?  313  LEU B HD11 1 
ATOM   10450 H HD12 . LEU B 1 347 ? -21.562 34.657  59.030 1.00 13.31 ?  313  LEU B HD12 1 
ATOM   10451 H HD13 . LEU B 1 347 ? -21.061 36.161  59.136 1.00 13.31 ?  313  LEU B HD13 1 
ATOM   10452 H HD21 . LEU B 1 347 ? -19.122 36.131  56.885 1.00 12.76 ?  313  LEU B HD21 1 
ATOM   10453 H HD22 . LEU B 1 347 ? -18.725 36.732  58.301 1.00 12.76 ?  313  LEU B HD22 1 
ATOM   10454 H HD23 . LEU B 1 347 ? -17.845 35.580  57.652 1.00 12.76 ?  313  LEU B HD23 1 
ATOM   10455 N N    . ALA B 1 348 ? -17.385 32.932  62.063 1.00 8.73  ?  314  ALA B N    1 
ATOM   10456 C CA   . ALA B 1 348 ? -16.874 32.867  63.429 1.00 8.70  ?  314  ALA B CA   1 
ATOM   10457 C C    . ALA B 1 348 ? -15.352 32.892  63.455 1.00 9.97  ?  314  ALA B C    1 
ATOM   10458 O O    . ALA B 1 348 ? -14.761 33.577  64.285 1.00 9.24  ?  314  ALA B O    1 
ATOM   10459 C CB   . ALA B 1 348 ? -17.426 31.619  64.127 1.00 9.79  ?  314  ALA B CB   1 
ATOM   10460 H H    . ALA B 1 348 ? -17.822 32.238  61.806 1.00 10.48 ?  314  ALA B H    1 
ATOM   10461 H HA   . ALA B 1 348 ? -17.182 33.642  63.924 1.00 10.43 ?  314  ALA B HA   1 
ATOM   10462 H HB1  . ALA B 1 348 ? -17.097 31.596  65.039 1.00 11.75 ?  314  ALA B HB1  1 
ATOM   10463 H HB2  . ALA B 1 348 ? -18.395 31.659  64.125 1.00 11.75 ?  314  ALA B HB2  1 
ATOM   10464 H HB3  . ALA B 1 348 ? -17.127 30.831  63.647 1.00 11.75 ?  314  ALA B HB3  1 
ATOM   10465 N N    . ILE B 1 349 ? -14.698 32.153  62.558 1.00 8.64  ?  315  ILE B N    1 
ATOM   10466 C CA   . ILE B 1 349 ? -13.241 32.237  62.460 1.00 9.59  ?  315  ILE B CA   1 
ATOM   10467 C C    . ILE B 1 349 ? -12.820 33.683  62.250 1.00 8.59  ?  315  ILE B C    1 
ATOM   10468 O O    . ILE B 1 349 ? -11.921 34.193  62.925 1.00 9.57  ?  315  ILE B O    1 
ATOM   10469 C CB   . ILE B 1 349 ? -12.718 31.333  61.332 1.00 8.09  ?  315  ILE B CB   1 
ATOM   10470 C CG1  . ILE B 1 349 ? -12.924 29.858  61.674 1.00 10.38 ?  315  ILE B CG1  1 
ATOM   10471 C CG2  . ILE B 1 349 ? -11.241 31.624  61.055 1.00 10.61 ?  315  ILE B CG2  1 
ATOM   10472 C CD1  . ILE B 1 349 ? -12.696 28.929  60.536 1.00 11.50 ?  315  ILE B CD1  1 
ATOM   10473 H H    . ILE B 1 349 ? -15.067 31.606  62.006 1.00 10.37 ?  315  ILE B H    1 
ATOM   10474 H HA   . ILE B 1 349 ? -12.856 31.922  63.294 1.00 11.51 ?  315  ILE B HA   1 
ATOM   10475 H HB   . ILE B 1 349 ? -13.227 31.529  60.530 1.00 9.70  ?  315  ILE B HB   1 
ATOM   10476 H HG12 . ILE B 1 349 ? -12.306 29.614  62.381 1.00 12.45 ?  315  ILE B HG12 1 
ATOM   10477 H HG13 . ILE B 1 349 ? -13.838 29.734  61.976 1.00 12.45 ?  315  ILE B HG13 1 
ATOM   10478 H HG21 . ILE B 1 349 ? -10.888 30.937  60.468 1.00 12.74 ?  315  ILE B HG21 1 
ATOM   10479 H HG22 . ILE B 1 349 ? -11.164 32.493  60.631 1.00 12.74 ?  315  ILE B HG22 1 
ATOM   10480 H HG23 . ILE B 1 349 ? -10.756 31.621  61.895 1.00 12.74 ?  315  ILE B HG23 1 
ATOM   10481 H HD11 . ILE B 1 349 ? -12.893 28.024  60.822 1.00 13.80 ?  315  ILE B HD11 1 
ATOM   10482 H HD12 . ILE B 1 349 ? -13.281 29.179  59.803 1.00 13.80 ?  315  ILE B HD12 1 
ATOM   10483 H HD13 . ILE B 1 349 ? -11.769 28.994  60.256 1.00 13.80 ?  315  ILE B HD13 1 
ATOM   10484 N N    . PHE B 1 350 ? -13.444 34.352  61.279 1.00 8.66  ?  316  PHE B N    1 
ATOM   10485 C CA   . PHE B 1 350 ? -13.124 35.746  61.013 1.00 8.14  ?  316  PHE B CA   1 
ATOM   10486 C C    . PHE B 1 350 ? -13.335 36.613  62.246 1.00 8.54  ?  316  PHE B C    1 
ATOM   10487 O O    . PHE B 1 350 ? -12.467 37.410  62.615 1.00 8.72  ?  316  PHE B O    1 
ATOM   10488 C CB   . PHE B 1 350 ? -13.997 36.242  59.854 1.00 7.78  ?  316  PHE B CB   1 
ATOM   10489 C CG   . PHE B 1 350 ? -13.912 37.723  59.640 1.00 7.56  ?  316  PHE B CG   1 
ATOM   10490 C CD1  . PHE B 1 350 ? -12.751 38.300  59.174 1.00 8.44  ?  316  PHE B CD1  1 
ATOM   10491 C CD2  . PHE B 1 350 ? -14.977 38.536  59.944 1.00 8.49  ?  316  PHE B CD2  1 
ATOM   10492 C CE1  . PHE B 1 350 ? -12.659 39.660  58.986 1.00 8.97  ?  316  PHE B CE1  1 
ATOM   10493 C CE2  . PHE B 1 350 ? -14.884 39.902  59.774 1.00 9.70  ?  316  PHE B CE2  1 
ATOM   10494 C CZ   . PHE B 1 350 ? -13.727 40.458  59.283 1.00 9.72  ?  316  PHE B CZ   1 
ATOM   10495 H H    . PHE B 1 350 ? -14.050 34.021  60.766 1.00 10.39 ?  316  PHE B H    1 
ATOM   10496 H HA   . PHE B 1 350 ? -12.190 35.818  60.762 1.00 9.77  ?  316  PHE B HA   1 
ATOM   10497 H HB2  . PHE B 1 350 ? -13.711 35.805  59.036 1.00 9.33  ?  316  PHE B HB2  1 
ATOM   10498 H HB3  . PHE B 1 350 ? -14.923 36.020  60.041 1.00 9.33  ?  316  PHE B HB3  1 
ATOM   10499 H HD1  . PHE B 1 350 ? -12.017 37.761  58.983 1.00 10.13 ?  316  PHE B HD1  1 
ATOM   10500 H HD2  . PHE B 1 350 ? -15.766 38.164  60.266 1.00 10.18 ?  316  PHE B HD2  1 
ATOM   10501 H HE1  . PHE B 1 350 ? -11.873 40.034  58.659 1.00 10.77 ?  316  PHE B HE1  1 
ATOM   10502 H HE2  . PHE B 1 350 ? -15.606 40.447  59.992 1.00 11.64 ?  316  PHE B HE2  1 
ATOM   10503 H HZ   . PHE B 1 350 ? -13.672 41.378  59.153 1.00 11.67 ?  316  PHE B HZ   1 
ATOM   10504 N N    . LEU B 1 351 ? -14.492 36.476  62.896 1.00 8.74  ?  317  LEU B N    1 
ATOM   10505 C CA   . LEU B 1 351 ? -14.824 37.371  63.999 1.00 9.69  ?  317  LEU B CA   1 
ATOM   10506 C C    . LEU B 1 351 ? -13.934 37.150  65.216 1.00 9.88  ?  317  LEU B C    1 
ATOM   10507 O O    . LEU B 1 351 ? -13.731 38.084  65.994 1.00 10.64 ?  317  LEU B O    1 
ATOM   10508 C CB   . LEU B 1 351 ? -16.305 37.234  64.359 1.00 10.69 ?  317  LEU B CB   1 
ATOM   10509 C CG   . LEU B 1 351 ? -17.279 37.814  63.326 1.00 9.54  ?  317  LEU B CG   1 
ATOM   10510 C CD1  . LEU B 1 351 ? -18.706 37.373  63.671 1.00 14.59 ?  317  LEU B CD1  1 
ATOM   10511 C CD2  . LEU B 1 351 ? -17.196 39.320  63.258 1.00 12.64 ?  317  LEU B CD2  1 
ATOM   10512 H H    . LEU B 1 351 ? -15.091 35.885  62.720 1.00 10.49 ?  317  LEU B H    1 
ATOM   10513 H HA   . LEU B 1 351 ? -14.677 38.285  63.710 1.00 11.62 ?  317  LEU B HA   1 
ATOM   10514 H HB2  . LEU B 1 351 ? -16.511 36.291  64.456 1.00 12.83 ?  317  LEU B HB2  1 
ATOM   10515 H HB3  . LEU B 1 351 ? -16.461 37.695  65.198 1.00 12.83 ?  317  LEU B HB3  1 
ATOM   10516 H HG   . LEU B 1 351 ? -17.040 37.480  62.448 1.00 11.45 ?  317  LEU B HG   1 
ATOM   10517 H HD11 . LEU B 1 351 ? -19.312 37.702  62.988 1.00 17.50 ?  317  LEU B HD11 1 
ATOM   10518 H HD12 . LEU B 1 351 ? -18.738 36.405  63.703 1.00 17.50 ?  317  LEU B HD12 1 
ATOM   10519 H HD13 . LEU B 1 351 ? -18.950 37.741  64.535 1.00 17.50 ?  317  LEU B HD13 1 
ATOM   10520 H HD21 . LEU B 1 351 ? -17.865 39.645  62.635 1.00 15.17 ?  317  LEU B HD21 1 
ATOM   10521 H HD22 . LEU B 1 351 ? -17.361 39.685  64.141 1.00 15.17 ?  317  LEU B HD22 1 
ATOM   10522 H HD23 . LEU B 1 351 ? -16.311 39.574  62.955 1.00 15.17 ?  317  LEU B HD23 1 
ATOM   10523 N N    . ILE B 1 352 ? -13.418 35.939  65.401 1.00 9.04  ?  318  ILE B N    1 
ATOM   10524 C CA   . ILE B 1 352 ? -12.458 35.667  66.473 1.00 11.76 ?  318  ILE B CA   1 
ATOM   10525 C C    . ILE B 1 352 ? -11.170 36.441  66.246 1.00 12.81 ?  318  ILE B C    1 
ATOM   10526 O O    . ILE B 1 352 ? -10.427 36.725  67.192 1.00 12.24 ?  318  ILE B O    1 
ATOM   10527 C CB   . ILE B 1 352 ? -12.230 34.131  66.553 1.00 12.63 ?  318  ILE B CB   1 
ATOM   10528 C CG1  . ILE B 1 352 ? -13.414 33.393  67.218 1.00 19.65 ?  318  ILE B CG1  1 
ATOM   10529 C CG2  . ILE B 1 352 ? -10.891 33.769  67.216 1.00 18.81 ?  318  ILE B CG2  1 
ATOM   10530 C CD1  . ILE B 1 352 ? -13.983 34.001  68.453 1.00 20.73 ?  318  ILE B CD1  1 
ATOM   10531 H H    . ILE B 1 352 ? -13.605 35.252  64.919 1.00 10.85 ?  318  ILE B H    1 
ATOM   10532 H HA   . ILE B 1 352 ? -12.812 35.966  67.325 1.00 14.11 ?  318  ILE B HA   1 
ATOM   10533 H HB   . ILE B 1 352 ? -12.185 33.823  65.635 1.00 15.16 ?  318  ILE B HB   1 
ATOM   10534 H HG12 . ILE B 1 352 ? -14.135 33.341  66.571 1.00 23.59 ?  318  ILE B HG12 1 
ATOM   10535 H HG13 . ILE B 1 352 ? -13.115 32.501  67.455 1.00 23.59 ?  318  ILE B HG13 1 
ATOM   10536 H HG21 . ILE B 1 352 ? -10.825 32.804  67.288 1.00 22.57 ?  318  ILE B HG21 1 
ATOM   10537 H HG22 . ILE B 1 352 ? -10.165 34.110  66.669 1.00 22.57 ?  318  ILE B HG22 1 
ATOM   10538 H HG23 . ILE B 1 352 ? -10.856 34.170  68.099 1.00 22.57 ?  318  ILE B HG23 1 
ATOM   10539 H HD11 . ILE B 1 352 ? -14.646 33.400  68.824 1.00 24.88 ?  318  ILE B HD11 1 
ATOM   10540 H HD12 . ILE B 1 352 ? -13.268 34.142  69.093 1.00 24.88 ?  318  ILE B HD12 1 
ATOM   10541 H HD13 . ILE B 1 352 ? -14.395 34.849  68.226 1.00 24.88 ?  318  ILE B HD13 1 
ATOM   10542 N N    . CYS B 1 353 ? -10.872 36.786  64.995 1.00 9.32  ?  319  CYS B N    1 
ATOM   10543 C CA   . CYS B 1 353 ? -9.640  37.492  64.660 1.00 10.24 ?  319  CYS B CA   1 
ATOM   10544 C C    . CYS B 1 353 ? -9.806  38.991  64.495 1.00 9.93  ?  319  CYS B C    1 
ATOM   10545 O O    . CYS B 1 353 ? -8.838  39.727  64.691 1.00 10.39 ?  319  CYS B O    1 
ATOM   10546 C CB   . CYS B 1 353 ? -9.081  36.989  63.322 1.00 9.82  ?  319  CYS B CB   1 
ATOM   10547 S SG   . CYS B 1 353 ? -8.609  35.254  63.324 1.00 10.13 ?  319  CYS B SG   1 
ATOM   10548 H H    . CYS B 1 353 ? -11.373 36.620  64.317 1.00 11.18 ?  319  CYS B H    1 
ATOM   10549 H HA   . CYS B 1 353 ? -9.012  37.313  65.377 1.00 12.29 ?  319  CYS B HA   1 
ATOM   10550 H HB2  . CYS B 1 353 ? -9.758  37.109  62.638 1.00 11.78 ?  319  CYS B HB2  1 
ATOM   10551 H HB3  . CYS B 1 353 ? -8.291  37.508  63.101 1.00 11.78 ?  319  CYS B HB3  1 
ATOM   10552 H HG   . CYS B 1 353 ? -9.589  34.583  63.497 1.00 12.16 ?  319  CYS B HG   1 
ATOM   10553 N N    . ALA B 1 354 ? -10.986 39.457  64.107 1.00 8.77  ?  320  ALA B N    1 
ATOM   10554 C CA   . ALA B 1 354 ? -11.151 40.764  63.498 1.00 9.27  ?  320  ALA B CA   1 
ATOM   10555 C C    . ALA B 1 354 ? -10.868 41.924  64.444 1.00 10.05 ?  320  ALA B C    1 
ATOM   10556 O O    . ALA B 1 354 ? -11.172 41.887  65.642 1.00 10.58 ?  320  ALA B O    1 
ATOM   10557 C CB   . ALA B 1 354 ? -12.586 40.899  63.012 1.00 10.26 ?  320  ALA B CB   1 
ATOM   10558 H H    . ALA B 1 354 ? -11.725 39.024  64.188 1.00 10.53 ?  320  ALA B H    1 
ATOM   10559 H HA   . ALA B 1 354 ? -10.514 40.831  62.769 1.00 11.13 ?  320  ALA B HA   1 
ATOM   10560 H HB1  . ALA B 1 354 ? -12.681 41.740  62.537 1.00 12.31 ?  320  ALA B HB1  1 
ATOM   10561 H HB2  . ALA B 1 354 ? -12.790 40.159  62.419 1.00 12.31 ?  320  ALA B HB2  1 
ATOM   10562 H HB3  . ALA B 1 354 ? -13.182 40.883  63.777 1.00 12.31 ?  320  ALA B HB3  1 
ATOM   10563 N N    . GLU B 1 355 ? -10.316 42.984  63.864 1.00 9.18  ?  321  GLU B N    1 
ATOM   10564 C CA   . GLU B 1 355 ? -10.228 44.298  64.495 1.00 9.05  ?  321  GLU B CA   1 
ATOM   10565 C C    . GLU B 1 355 ? -10.689 45.341  63.488 1.00 10.06 ?  321  GLU B C    1 
ATOM   10566 O O    . GLU B 1 355 ? -11.074 45.011  62.367 1.00 9.89  ?  321  GLU B O    1 
ATOM   10567 C CB   . GLU B 1 355 ? -8.814  44.584  65.005 1.00 11.18 ?  321  GLU B CB   1 
ATOM   10568 C CG   . GLU B 1 355 ? -8.345  43.628  66.078 1.00 11.42 ?  321  GLU B CG   1 
ATOM   10569 C CD   . GLU B 1 355 ? -9.118  43.751  67.389 1.00 12.32 ?  321  GLU B CD   1 
ATOM   10570 O OE1  . GLU B 1 355 ? -9.726  44.818  67.630 1.00 15.57 ?  321  GLU B OE1  1 
ATOM   10571 O OE2  . GLU B 1 355 ? -9.121  42.768  68.160 1.00 13.34 ?  321  GLU B OE2  1 
ATOM   10572 H H    . GLU B 1 355 ? -9.973  42.967  63.076 1.00 11.02 ?  321  GLU B H    1 
ATOM   10573 H HA   . GLU B 1 355 ? -10.819 44.333  65.263 1.00 10.85 ?  321  GLU B HA   1 
ATOM   10574 H HB2  . GLU B 1 355 ? -8.196  44.520  64.260 1.00 13.42 ?  321  GLU B HB2  1 
ATOM   10575 H HB3  . GLU B 1 355 ? -8.793  45.480  65.377 1.00 13.42 ?  321  GLU B HB3  1 
ATOM   10576 H HG2  . GLU B 1 355 ? -8.452  42.719  65.756 1.00 13.71 ?  321  GLU B HG2  1 
ATOM   10577 H HG3  . GLU B 1 355 ? -7.410  43.805  66.268 1.00 13.71 ?  321  GLU B HG3  1 
ATOM   10578 N N    . LYS B 1 356 ? -10.645 46.619  63.863 1.00 10.65 ?  322  LYS B N    1 
ATOM   10579 C CA   . LYS B 1 356 ? -10.891 47.671  62.888 1.00 11.08 ?  322  LYS B CA   1 
ATOM   10580 C C    . LYS B 1 356 ? -10.018 47.416  61.668 1.00 9.70  ?  322  LYS B C    1 
ATOM   10581 O O    . LYS B 1 356 ? -8.846  47.074  61.794 1.00 9.85  ?  322  LYS B O    1 
ATOM   10582 C CB   . LYS B 1 356 ? -10.596 49.042  63.508 1.00 13.48 ?  322  LYS B CB   1 
ATOM   10583 C CG   . LYS B 1 356 ? -11.074 50.249  62.703 1.00 14.73 ?  322  LYS B CG   1 
ATOM   10584 C CD   . LYS B 1 356 ? -10.810 51.528  63.520 1.00 17.67 ?  322  LYS B CD   1 
ATOM   10585 C CE   . LYS B 1 356 ? -11.857 52.596  63.289 1.00 29.26 ?  322  LYS B CE   1 
ATOM   10586 N NZ   . LYS B 1 356 ? -11.248 53.938  63.065 1.00 31.23 ?  322  LYS B NZ   1 
ATOM   10587 H H    . LYS B 1 356 ? -10.479 46.895  64.661 1.00 12.77 ?  322  LYS B H    1 
ATOM   10588 H HA   . LYS B 1 356 ? -11.821 47.680  62.615 1.00 13.30 ?  322  LYS B HA   1 
ATOM   10589 H HB2  . LYS B 1 356 ? -11.030 49.084  64.374 1.00 16.18 ?  322  LYS B HB2  1 
ATOM   10590 H HB3  . LYS B 1 356 ? -9.636  49.129  63.613 1.00 16.18 ?  322  LYS B HB3  1 
ATOM   10591 H HG2  . LYS B 1 356 ? -10.587 50.303  61.865 1.00 17.67 ?  322  LYS B HG2  1 
ATOM   10592 H HG3  . LYS B 1 356 ? -12.026 50.176  62.529 1.00 17.67 ?  322  LYS B HG3  1 
ATOM   10593 H HD2  . LYS B 1 356 ? -10.811 51.306  64.464 1.00 21.21 ?  322  LYS B HD2  1 
ATOM   10594 H HD3  . LYS B 1 356 ? -9.948  51.894  63.266 1.00 21.21 ?  322  LYS B HD3  1 
ATOM   10595 H HE2  . LYS B 1 356 ? -12.380 52.367  62.505 1.00 35.11 ?  322  LYS B HE2  1 
ATOM   10596 H HE3  . LYS B 1 356 ? -12.433 52.652  64.068 1.00 35.11 ?  322  LYS B HE3  1 
ATOM   10597 H HZ1  . LYS B 1 356 ? -11.886 54.541  62.916 1.00 37.48 ?  322  LYS B HZ1  1 
ATOM   10598 H HZ2  . LYS B 1 356 ? -10.781 54.184  63.781 1.00 37.48 ?  322  LYS B HZ2  1 
ATOM   10599 H HZ3  . LYS B 1 356 ? -10.705 53.912  62.361 1.00 37.48 ?  322  LYS B HZ3  1 
ATOM   10600 N N    . TYR B 1 357 ? -10.620 47.528  60.487 1.00 10.36 ?  323  TYR B N    1 
ATOM   10601 C CA   . TYR B 1 357 ? -9.955  47.341  59.197 1.00 8.87  ?  323  TYR B CA   1 
ATOM   10602 C C    . TYR B 1 357 ? -9.707  45.873  58.854 1.00 9.51  ?  323  TYR B C    1 
ATOM   10603 O O    . TYR B 1 357 ? -8.854  45.567  58.000 1.00 9.45  ?  323  TYR B O    1 
ATOM   10604 C CB   . TYR B 1 357 ? -8.673  48.168  59.080 1.00 11.02 ?  323  TYR B CB   1 
ATOM   10605 C CG   . TYR B 1 357 ? -8.862  49.612  59.455 1.00 11.11 ?  323  TYR B CG   1 
ATOM   10606 C CD1  . TYR B 1 357 ? -9.756  50.413  58.763 1.00 12.35 ?  323  TYR B CD1  1 
ATOM   10607 C CD2  . TYR B 1 357 ? -8.136  50.178  60.498 1.00 11.85 ?  323  TYR B CD2  1 
ATOM   10608 C CE1  . TYR B 1 357 ? -9.920  51.756  59.101 1.00 15.38 ?  323  TYR B CE1  1 
ATOM   10609 C CE2  . TYR B 1 357 ? -8.300  51.519  60.831 1.00 14.73 ?  323  TYR B CE2  1 
ATOM   10610 C CZ   . TYR B 1 357 ? -9.196  52.276  60.135 1.00 14.01 ?  323  TYR B CZ   1 
ATOM   10611 O OH   . TYR B 1 357 ? -9.344  53.618  60.469 1.00 20.82 ?  323  TYR B OH   1 
ATOM   10612 H H    . TYR B 1 357 ? -11.454 47.722  60.403 1.00 12.43 ?  323  TYR B H    1 
ATOM   10613 H HA   . TYR B 1 357 ? -10.554 47.669  58.508 1.00 10.64 ?  323  TYR B HA   1 
ATOM   10614 H HB2  . TYR B 1 357 ? -8.002  47.792  59.671 1.00 13.22 ?  323  TYR B HB2  1 
ATOM   10615 H HB3  . TYR B 1 357 ? -8.362  48.137  58.162 1.00 13.22 ?  323  TYR B HB3  1 
ATOM   10616 H HD1  . TYR B 1 357 ? -10.251 50.051  58.064 1.00 14.82 ?  323  TYR B HD1  1 
ATOM   10617 H HD2  . TYR B 1 357 ? -7.535  49.654  60.977 1.00 14.22 ?  323  TYR B HD2  1 
ATOM   10618 H HE1  . TYR B 1 357 ? -10.516 52.292  58.628 1.00 18.46 ?  323  TYR B HE1  1 
ATOM   10619 H HE2  . TYR B 1 357 ? -7.803  51.895  61.522 1.00 17.68 ?  323  TYR B HE2  1 
ATOM   10620 H HH   . TYR B 1 357 ? -9.801  54.011  59.884 1.00 24.98 ?  323  TYR B HH   1 
ATOM   10621 N N    . SER B 1 358 ? -10.451 44.963  59.478 1.00 9.44  ?  324  SER B N    1 
ATOM   10622 C CA   . SER B 1 358 ? -10.552 43.570  59.066 1.00 7.60  ?  324  SER B CA   1 
ATOM   10623 C C    . SER B 1 358 ? -11.837 43.394  58.271 1.00 8.88  ?  324  SER B C    1 
ATOM   10624 O O    . SER B 1 358 ? -12.905 43.854  58.685 1.00 9.18  ?  324  SER B O    1 
ATOM   10625 C CB   . SER B 1 358 ? -10.609 42.662  60.297 1.00 9.22  ?  324  SER B CB   1 
ATOM   10626 O OG   . SER B 1 358 ? -9.383  42.643  61.032 1.00 9.25  ?  324  SER B OG   1 
ATOM   10627 H H    . SER B 1 358 ? -10.927 45.139  60.172 1.00 11.33 ?  324  SER B H    1 
ATOM   10628 H HA   . SER B 1 358 ? -9.788  43.320  58.522 1.00 9.12  ?  324  SER B HA   1 
ATOM   10629 H HB2  . SER B 1 358 ? -11.313 42.983  60.883 1.00 11.06 ?  324  SER B HB2  1 
ATOM   10630 H HB3  . SER B 1 358 ? -10.807 41.759  60.004 1.00 11.06 ?  324  SER B HB3  1 
ATOM   10631 H HG   . SER B 1 358 ? -9.011  43.395  60.990 1.00 11.10 ?  324  SER B HG   1 
ATOM   10632 N N    . TYR B 1 359 ? -11.747 42.671  57.150 1.00 8.20  ?  325  TYR B N    1 
ATOM   10633 C CA   . TYR B 1 359 ? -12.851 42.477  56.226 1.00 8.48  ?  325  TYR B CA   1 
ATOM   10634 C C    . TYR B 1 359 ? -12.837 41.031  55.753 1.00 7.57  ?  325  TYR B C    1 
ATOM   10635 O O    . TYR B 1 359 ? -11.768 40.422  55.625 1.00 9.34  ?  325  TYR B O    1 
ATOM   10636 C CB   . TYR B 1 359 ? -12.708 43.410  54.989 1.00 7.68  ?  325  TYR B CB   1 
ATOM   10637 C CG   . TYR B 1 359 ? -12.502 44.871  55.320 1.00 8.47  ?  325  TYR B CG   1 
ATOM   10638 C CD1  . TYR B 1 359 ? -11.229 45.381  55.532 1.00 7.51  ?  325  TYR B CD1  1 
ATOM   10639 C CD2  . TYR B 1 359 ? -13.578 45.728  55.412 1.00 7.66  ?  325  TYR B CD2  1 
ATOM   10640 C CE1  . TYR B 1 359 ? -11.036 46.710  55.867 1.00 9.83  ?  325  TYR B CE1  1 
ATOM   10641 C CE2  . TYR B 1 359 ? -13.406 47.069  55.731 1.00 9.90  ?  325  TYR B CE2  1 
ATOM   10642 C CZ   . TYR B 1 359 ? -12.138 47.546  55.936 1.00 8.34  ?  325  TYR B CZ   1 
ATOM   10643 O OH   . TYR B 1 359 ? -11.904 48.865  56.278 1.00 9.96  ?  325  TYR B OH   1 
ATOM   10644 H H    . TYR B 1 359 ? -11.028 42.271  56.900 1.00 9.84  ?  325  TYR B H    1 
ATOM   10645 H HA   . TYR B 1 359 ? -13.694 42.662  56.669 1.00 10.17 ?  325  TYR B HA   1 
ATOM   10646 H HB2  . TYR B 1 359 ? -11.943 43.118  54.469 1.00 9.22  ?  325  TYR B HB2  1 
ATOM   10647 H HB3  . TYR B 1 359 ? -13.516 43.342  54.456 1.00 9.22  ?  325  TYR B HB3  1 
ATOM   10648 H HD1  . TYR B 1 359 ? -10.493 44.819  55.447 1.00 9.02  ?  325  TYR B HD1  1 
ATOM   10649 H HD2  . TYR B 1 359 ? -14.436 45.403  55.257 1.00 9.20  ?  325  TYR B HD2  1 
ATOM   10650 H HE1  . TYR B 1 359 ? -10.182 47.035  56.042 1.00 11.80 ?  325  TYR B HE1  1 
ATOM   10651 H HE2  . TYR B 1 359 ? -14.140 47.635  55.805 1.00 11.89 ?  325  TYR B HE2  1 
ATOM   10652 H HH   . TYR B 1 359 ? -12.596 49.323  56.144 1.00 11.95 ?  325  TYR B HH   1 
ATOM   10653 N N    . VAL B 1 360 ? -14.018 40.476  55.460 1.00 7.79  ?  326  VAL B N    1 
ATOM   10654 C CA   . VAL B 1 360 ? -14.160 39.059  55.116 1.00 7.88  ?  326  VAL B CA   1 
ATOM   10655 C C    . VAL B 1 360 ? -14.841 38.873  53.765 1.00 8.11  ?  326  VAL B C    1 
ATOM   10656 O O    . VAL B 1 360 ? -15.742 39.627  53.384 1.00 8.45  ?  326  VAL B O    1 
ATOM   10657 C CB   . VAL B 1 360 ? -14.916 38.305  56.246 1.00 8.07  ?  326  VAL B CB   1 
ATOM   10658 C CG1  . VAL B 1 360 ? -16.369 38.715  56.331 1.00 9.20  ?  326  VAL B CG1  1 
ATOM   10659 C CG2  . VAL B 1 360 ? -14.822 36.798  56.089 1.00 9.25  ?  326  VAL B CG2  1 
ATOM   10660 H H    . VAL B 1 360 ? -14.762 40.908  55.455 1.00 9.35  ?  326  VAL B H    1 
ATOM   10661 H HA   . VAL B 1 360 ? -13.275 38.679  55.002 1.00 9.46  ?  326  VAL B HA   1 
ATOM   10662 H HB   . VAL B 1 360 ? -14.480 38.554  57.076 1.00 9.68  ?  326  VAL B HB   1 
ATOM   10663 H HG11 . VAL B 1 360 ? -16.730 38.423  57.182 1.00 11.04 ?  326  VAL B HG11 1 
ATOM   10664 H HG12 . VAL B 1 360 ? -16.429 39.680  56.259 1.00 11.04 ?  326  VAL B HG12 1 
ATOM   10665 H HG13 . VAL B 1 360 ? -16.857 38.298  55.604 1.00 11.04 ?  326  VAL B HG13 1 
ATOM   10666 H HG21 . VAL B 1 360 ? -15.141 36.375  56.901 1.00 11.10 ?  326  VAL B HG21 1 
ATOM   10667 H HG22 . VAL B 1 360 ? -15.370 36.525  55.336 1.00 11.10 ?  326  VAL B HG22 1 
ATOM   10668 H HG23 . VAL B 1 360 ? -13.897 36.554  55.930 1.00 11.10 ?  326  VAL B HG23 1 
ATOM   10669 N N    . TYR B 1 361 ? -14.429 37.817  53.066 1.00 7.18  ?  327  TYR B N    1 
ATOM   10670 C CA   . TYR B 1 361 ? -15.083 37.363  51.839 1.00 8.47  ?  327  TYR B CA   1 
ATOM   10671 C C    . TYR B 1 361 ? -15.200 35.845  51.869 1.00 8.28  ?  327  TYR B C    1 
ATOM   10672 O O    . TYR B 1 361 ? -14.188 35.138  51.791 1.00 8.46  ?  327  TYR B O    1 
ATOM   10673 C CB   . TYR B 1 361 ? -14.319 37.800  50.595 1.00 7.62  ?  327  TYR B CB   1 
ATOM   10674 C CG   . TYR B 1 361 ? -14.999 37.520  49.255 1.00 8.66  ?  327  TYR B CG   1 
ATOM   10675 C CD1  . TYR B 1 361 ? -16.357 37.240  49.162 1.00 8.80  ?  327  TYR B CD1  1 
ATOM   10676 C CD2  . TYR B 1 361 ? -14.274 37.584  48.079 1.00 8.92  ?  327  TYR B CD2  1 
ATOM   10677 C CE1  . TYR B 1 361 ? -16.975 37.033  47.924 1.00 9.45  ?  327  TYR B CE1  1 
ATOM   10678 C CE2  . TYR B 1 361 ? -14.879 37.382  46.843 1.00 8.21  ?  327  TYR B CE2  1 
ATOM   10679 C CZ   . TYR B 1 361 ? -16.220 37.105  46.774 1.00 7.64  ?  327  TYR B CZ   1 
ATOM   10680 O OH   . TYR B 1 361 ? -16.844 36.893  45.555 1.00 10.24 ?  327  TYR B OH   1 
ATOM   10681 H H    . TYR B 1 361 ? -13.754 37.332  53.289 1.00 8.62  ?  327  TYR B H    1 
ATOM   10682 H HA   . TYR B 1 361 ? -15.975 37.744  51.814 1.00 10.16 ?  327  TYR B HA   1 
ATOM   10683 H HB2  . TYR B 1 361 ? -14.175 38.758  50.648 1.00 9.15  ?  327  TYR B HB2  1 
ATOM   10684 H HB3  . TYR B 1 361 ? -13.466 37.336  50.585 1.00 9.15  ?  327  TYR B HB3  1 
ATOM   10685 H HD1  . TYR B 1 361 ? -16.865 37.190  49.939 1.00 10.56 ?  327  TYR B HD1  1 
ATOM   10686 H HD2  . TYR B 1 361 ? -13.362 37.765  48.116 1.00 10.71 ?  327  TYR B HD2  1 
ATOM   10687 H HE1  . TYR B 1 361 ? -17.886 36.849  47.879 1.00 11.35 ?  327  TYR B HE1  1 
ATOM   10688 H HE2  . TYR B 1 361 ? -14.375 37.434  46.064 1.00 9.85  ?  327  TYR B HE2  1 
ATOM   10689 H HH   . TYR B 1 361 ? -16.284 36.952  44.931 1.00 12.28 ?  327  TYR B HH   1 
ATOM   10690 N N    . LEU B 1 362 ? -16.431 35.352  51.969 1.00 7.77  ?  328  LEU B N    1 
ATOM   10691 C CA   . LEU B 1 362 ? -16.752 33.936  51.795 1.00 8.19  ?  328  LEU B CA   1 
ATOM   10692 C C    . LEU B 1 362 ? -17.152 33.718  50.343 1.00 8.29  ?  328  LEU B C    1 
ATOM   10693 O O    . LEU B 1 362 ? -18.170 34.245  49.883 1.00 9.75  ?  328  LEU B O    1 
ATOM   10694 C CB   . LEU B 1 362 ? -17.908 33.541  52.708 1.00 9.47  ?  328  LEU B CB   1 
ATOM   10695 C CG   . LEU B 1 362 ? -17.747 33.907  54.178 1.00 10.17 ?  328  LEU B CG   1 
ATOM   10696 C CD1  . LEU B 1 362 ? -18.924 33.310  54.932 1.00 11.99 ?  328  LEU B CD1  1 
ATOM   10697 C CD2  . LEU B 1 362 ? -16.412 33.470  54.729 1.00 10.98 ?  328  LEU B CD2  1 
ATOM   10698 H H    . LEU B 1 362 ? -17.122 35.834  52.143 1.00 9.32  ?  328  LEU B H    1 
ATOM   10699 H HA   . LEU B 1 362 ? -15.974 33.397  52.007 1.00 9.83  ?  328  LEU B HA   1 
ATOM   10700 H HB2  . LEU B 1 362 ? -18.710 33.981  52.388 1.00 11.37 ?  328  LEU B HB2  1 
ATOM   10701 H HB3  . LEU B 1 362 ? -18.016 32.578  52.661 1.00 11.37 ?  328  LEU B HB3  1 
ATOM   10702 H HG   . LEU B 1 362 ? -17.752 34.870  54.297 1.00 12.20 ?  328  LEU B HG   1 
ATOM   10703 H HD11 . LEU B 1 362 ? -18.827 33.507  55.877 1.00 14.39 ?  328  LEU B HD11 1 
ATOM   10704 H HD12 . LEU B 1 362 ? -19.746 33.700  54.595 1.00 14.39 ?  328  LEU B HD12 1 
ATOM   10705 H HD13 . LEU B 1 362 ? -18.933 32.349  54.793 1.00 14.39 ?  328  LEU B HD13 1 
ATOM   10706 H HD21 . LEU B 1 362 ? -16.415 33.585  55.692 1.00 13.18 ?  328  LEU B HD21 1 
ATOM   10707 H HD22 . LEU B 1 362 ? -16.269 32.537  54.508 1.00 13.18 ?  328  LEU B HD22 1 
ATOM   10708 H HD23 . LEU B 1 362 ? -15.713 34.015  54.333 1.00 13.18 ?  328  LEU B HD23 1 
ATOM   10709 N N    . HIS B 1 363 ? -16.353 32.971  49.606 1.00 8.32  ?  329  HIS B N    1 
ATOM   10710 C CA   . HIS B 1 363 ? -16.418 33.026  48.151 1.00 6.83  ?  329  HIS B CA   1 
ATOM   10711 C C    . HIS B 1 363 ? -16.631 31.662  47.511 1.00 8.68  ?  329  HIS B C    1 
ATOM   10712 O O    . HIS B 1 363 ? -16.413 30.603  48.113 1.00 8.86  ?  329  HIS B O    1 
ATOM   10713 C CB   . HIS B 1 363 ? -15.142 33.669  47.576 1.00 7.82  ?  329  HIS B CB   1 
ATOM   10714 C CG   . HIS B 1 363 ? -13.913 32.850  47.789 1.00 9.12  ?  329  HIS B CG   1 
ATOM   10715 N ND1  . HIS B 1 363 ? -13.578 31.791  46.981 1.00 8.84  ?  329  HIS B ND1  1 
ATOM   10716 C CD2  . HIS B 1 363 ? -12.945 32.928  48.731 1.00 9.58  ?  329  HIS B CD2  1 
ATOM   10717 C CE1  . HIS B 1 363 ? -12.457 31.244  47.421 1.00 10.00 ?  329  HIS B CE1  1 
ATOM   10718 N NE2  . HIS B 1 363 ? -12.044 31.931  48.470 1.00 9.70  ?  329  HIS B NE2  1 
ATOM   10719 H H    . HIS B 1 363 ? -15.767 32.426  49.921 1.00 9.98  ?  329  HIS B H    1 
ATOM   10720 H HA   . HIS B 1 363 ? -17.195 33.557  47.914 1.00 8.20  ?  329  HIS B HA   1 
ATOM   10721 H HB2  . HIS B 1 363 ? -15.256 33.789  46.621 1.00 9.39  ?  329  HIS B HB2  1 
ATOM   10722 H HB3  . HIS B 1 363 ? -15.004 34.528  48.005 1.00 9.39  ?  329  HIS B HB3  1 
ATOM   10723 H HD2  . HIS B 1 363 ? -12.900 33.544  49.426 1.00 11.49 ?  329  HIS B HD2  1 
ATOM   10724 H HE1  . HIS B 1 363 ? -12.033 30.502  47.054 1.00 12.00 ?  329  HIS B HE1  1 
ATOM   10725 H HE2  . HIS B 1 363 ? -11.325 31.777  48.917 1.00 11.64 ?  329  HIS B HE2  1 
ATOM   10726 N N    . ASP B 1 364 ? -17.044 31.719  46.246 1.00 8.73  ?  330  ASP B N    1 
ATOM   10727 C CA   . ASP B 1 364 ? -17.108 30.571  45.351 1.00 7.83  ?  330  ASP B CA   1 
ATOM   10728 C C    . ASP B 1 364 ? -16.251 30.929  44.140 1.00 7.78  ?  330  ASP B C    1 
ATOM   10729 O O    . ASP B 1 364 ? -16.726 30.917  42.998 1.00 8.40  ?  330  ASP B O    1 
ATOM   10730 C CB   . ASP B 1 364 ? -18.561 30.277  44.962 1.00 7.20  ?  330  ASP B CB   1 
ATOM   10731 C CG   . ASP B 1 364 ? -18.702 29.053  44.067 1.00 9.41  ?  330  ASP B CG   1 
ATOM   10732 O OD1  . ASP B 1 364 ? -17.832 28.156  44.093 1.00 11.22 ?  330  ASP B OD1  1 
ATOM   10733 O OD2  . ASP B 1 364 ? -19.703 29.018  43.310 1.00 9.75  ?  330  ASP B OD2  1 
ATOM   10734 H H    . ASP B 1 364 ? -17.303 32.446  45.866 1.00 10.47 ?  330  ASP B H    1 
ATOM   10735 H HA   . ASP B 1 364 ? -16.780 29.756  45.763 1.00 9.39  ?  330  ASP B HA   1 
ATOM   10736 H HB2  . ASP B 1 364 ? -19.077 30.120  45.768 1.00 8.64  ?  330  ASP B HB2  1 
ATOM   10737 H HB3  . ASP B 1 364 ? -18.919 31.041  44.482 1.00 8.64  ?  330  ASP B HB3  1 
ATOM   10738 N N    . GLY B 1 365 ? -14.982 31.241  44.387 1.00 7.43  ?  331  GLY B N    1 
ATOM   10739 C CA   . GLY B 1 365 ? -14.068 31.663  43.345 1.00 7.39  ?  331  GLY B CA   1 
ATOM   10740 C C    . GLY B 1 365 ? -14.176 33.144  43.044 1.00 8.96  ?  331  GLY B C    1 
ATOM   10741 O O    . GLY B 1 365 ? -15.155 33.807  43.380 1.00 10.44 ?  331  GLY B O    1 
ATOM   10742 H H    . GLY B 1 365 ? -14.624 31.214  45.169 1.00 8.91  ?  331  GLY B H    1 
ATOM   10743 H HA2  . GLY B 1 365 ? -13.158 31.473  43.621 1.00 8.87  ?  331  GLY B HA2  1 
ATOM   10744 H HA3  . GLY B 1 365 ? -14.261 31.171  42.532 1.00 8.87  ?  331  GLY B HA3  1 
ATOM   10745 N N    . TYR B 1 366 ? -13.147 33.671  42.391 1.00 7.71  ?  332  TYR B N    1 
ATOM   10746 C CA   . TYR B 1 366 ? -13.074 35.102  42.145 1.00 7.81  ?  332  TYR B CA   1 
ATOM   10747 C C    . TYR B 1 366 ? -13.645 35.512  40.802 1.00 9.47  ?  332  TYR B C    1 
ATOM   10748 O O    . TYR B 1 366 ? -13.849 36.710  40.585 1.00 12.92 ?  332  TYR B O    1 
ATOM   10749 C CB   . TYR B 1 366 ? -11.639 35.604  42.340 1.00 8.59  ?  332  TYR B CB   1 
ATOM   10750 C CG   . TYR B 1 366 ? -11.110 35.344  43.749 1.00 7.87  ?  332  TYR B CG   1 
ATOM   10751 C CD1  . TYR B 1 366 ? -11.932 35.483  44.849 1.00 8.81  ?  332  TYR B CD1  1 
ATOM   10752 C CD2  . TYR B 1 366 ? -9.791  35.004  43.973 1.00 8.13  ?  332  TYR B CD2  1 
ATOM   10753 C CE1  . TYR B 1 366 ? -11.454 35.264  46.139 1.00 8.20  ?  332  TYR B CE1  1 
ATOM   10754 C CE2  . TYR B 1 366 ? -9.317  34.772  45.249 1.00 8.25  ?  332  TYR B CE2  1 
ATOM   10755 C CZ   . TYR B 1 366 ? -10.157 34.908  46.316 1.00 7.90  ?  332  TYR B CZ   1 
ATOM   10756 O OH   . TYR B 1 366 ? -9.754  34.703  47.605 1.00 9.75  ?  332  TYR B OH   1 
ATOM   10757 H H    . TYR B 1 366 ? -12.482 33.221  42.082 1.00 9.25  ?  332  TYR B H    1 
ATOM   10758 H HA   . TYR B 1 366 ? -13.608 35.568  42.808 1.00 9.37  ?  332  TYR B HA   1 
ATOM   10759 H HB2  . TYR B 1 366 ? -11.057 35.148  41.711 1.00 10.31 ?  332  TYR B HB2  1 
ATOM   10760 H HB3  . TYR B 1 366 ? -11.614 36.560  42.181 1.00 10.31 ?  332  TYR B HB3  1 
ATOM   10761 H HD1  . TYR B 1 366 ? -12.821 35.727  44.727 1.00 10.57 ?  332  TYR B HD1  1 
ATOM   10762 H HD2  . TYR B 1 366 ? -9.211  34.929  43.250 1.00 9.75  ?  332  TYR B HD2  1 
ATOM   10763 H HE1  . TYR B 1 366 ? -12.018 35.362  46.872 1.00 9.84  ?  332  TYR B HE1  1 
ATOM   10764 H HE2  . TYR B 1 366 ? -8.430  34.525  45.380 1.00 9.90  ?  332  TYR B HE2  1 
ATOM   10765 H HH   . TYR B 1 366 ? -8.956  34.442  47.618 1.00 11.70 ?  332  TYR B HH   1 
ATOM   10766 N N    . LEU B 1 367 ? -13.959 34.579  39.916 1.00 7.80  ?  333  LEU B N    1 
ATOM   10767 C CA   . LEU B 1 367 ? -14.607 34.902  38.646 1.00 6.94  ?  333  LEU B CA   1 
ATOM   10768 C C    . LEU B 1 367 ? -16.104 35.107  38.865 1.00 6.96  ?  333  LEU B C    1 
ATOM   10769 O O    . LEU B 1 367 ? -16.823 34.179  39.246 1.00 8.18  ?  333  LEU B O    1 
ATOM   10770 C CB   . LEU B 1 367 ? -14.357 33.794  37.635 1.00 7.43  ?  333  LEU B CB   1 
ATOM   10771 C CG   . LEU B 1 367 ? -15.081 33.968  36.290 1.00 7.58  ?  333  LEU B CG   1 
ATOM   10772 C CD1  . LEU B 1 367 ? -14.721 35.265  35.613 1.00 9.06  ?  333  LEU B CD1  1 
ATOM   10773 C CD2  . LEU B 1 367 ? -14.772 32.775  35.396 1.00 9.95  ?  333  LEU B CD2  1 
ATOM   10774 H H    . LEU B 1 367 ? -13.807 33.740  40.024 1.00 9.35  ?  333  LEU B H    1 
ATOM   10775 H HA   . LEU B 1 367 ? -14.237 35.727  38.296 1.00 8.33  ?  333  LEU B HA   1 
ATOM   10776 H HB2  . LEU B 1 367 ? -13.405 33.756  37.451 1.00 8.91  ?  333  LEU B HB2  1 
ATOM   10777 H HB3  . LEU B 1 367 ? -14.654 32.955  38.020 1.00 8.91  ?  333  LEU B HB3  1 
ATOM   10778 H HG   . LEU B 1 367 ? -16.036 34.008  36.450 1.00 9.09  ?  333  LEU B HG   1 
ATOM   10779 H HD11 . LEU B 1 367 ? -15.158 35.300  34.747 1.00 10.88 ?  333  LEU B HD11 1 
ATOM   10780 H HD12 . LEU B 1 367 ? -15.021 36.003  36.165 1.00 10.88 ?  333  LEU B HD12 1 
ATOM   10781 H HD13 . LEU B 1 367 ? -13.759 35.306  35.500 1.00 10.88 ?  333  LEU B HD13 1 
ATOM   10782 H HD21 . LEU B 1 367 ? -15.252 32.875  34.559 1.00 11.94 ?  333  LEU B HD21 1 
ATOM   10783 H HD22 . LEU B 1 367 ? -13.817 32.745  35.228 1.00 11.94 ?  333  LEU B HD22 1 
ATOM   10784 H HD23 . LEU B 1 367 ? -15.055 31.963  35.845 1.00 11.94 ?  333  LEU B HD23 1 
ATOM   10785 N N    . ALA B 1 368 ? -16.586 36.323  38.609 1.00 7.33  ?  334  ALA B N    1 
ATOM   10786 C CA   . ALA B 1 368 ? -17.964 36.664  38.937 1.00 8.32  ?  334  ALA B CA   1 
ATOM   10787 C C    . ALA B 1 368 ? -18.963 35.734  38.269 1.00 8.65  ?  334  ALA B C    1 
ATOM   10788 O O    . ALA B 1 368 ? -19.942 35.309  38.903 1.00 9.79  ?  334  ALA B O    1 
ATOM   10789 C CB   . ALA B 1 368 ? -18.244 38.111  38.530 1.00 9.97  ?  334  ALA B CB   1 
ATOM   10790 H H    . ALA B 1 368 ? -16.137 36.963  38.249 1.00 8.79  ?  334  ALA B H    1 
ATOM   10791 H HA   . ALA B 1 368 ? -18.078 36.574  39.896 1.00 9.98  ?  334  ALA B HA   1 
ATOM   10792 H HB1  . ALA B 1 368 ? -19.175 38.315  38.713 1.00 11.97 ?  334  ALA B HB1  1 
ATOM   10793 H HB2  . ALA B 1 368 ? -17.669 38.700  39.043 1.00 11.97 ?  334  ALA B HB2  1 
ATOM   10794 H HB3  . ALA B 1 368 ? -18.063 38.213  37.583 1.00 11.97 ?  334  ALA B HB3  1 
ATOM   10795 N N    . THR B 1 369 ? -18.745 35.408  36.988 1.00 8.58  ?  335  THR B N    1 
ATOM   10796 C CA   . THR B 1 369 ? -19.718 34.659  36.206 1.00 9.14  ?  335  THR B CA   1 
ATOM   10797 C C    . THR B 1 369 ? -19.755 33.173  36.550 1.00 9.40  ?  335  THR B C    1 
ATOM   10798 O O    . THR B 1 369 ? -20.625 32.452  36.030 1.00 10.23 ?  335  THR B O    1 
ATOM   10799 C CB   . THR B 1 369 ? -19.415 34.853  34.715 1.00 9.12  ?  335  THR B CB   1 
ATOM   10800 O OG1  . THR B 1 369 ? -18.010 34.671  34.493 1.00 8.90  ?  335  THR B OG1  1 
ATOM   10801 C CG2  . THR B 1 369 ? -19.769 36.250  34.253 1.00 10.53 ?  335  THR B CG2  1 
ATOM   10802 H H    . THR B 1 369 ? -18.033 35.614  36.552 1.00 10.30 ?  335  THR B H    1 
ATOM   10803 H HA   . THR B 1 369 ? -20.606 35.007  36.385 1.00 10.97 ?  335  THR B HA   1 
ATOM   10804 H HB   . THR B 1 369 ? -19.939 34.212  34.210 1.00 10.94 ?  335  THR B HB   1 
ATOM   10805 H HG1  . THR B 1 369 ? -17.795 33.875  34.650 1.00 10.68 ?  335  THR B HG1  1 
ATOM   10806 H HG21 . THR B 1 369 ? -19.475 36.381  33.338 1.00 12.63 ?  335  THR B HG21 1 
ATOM   10807 H HG22 . THR B 1 369 ? -20.729 36.380  34.296 1.00 12.63 ?  335  THR B HG22 1 
ATOM   10808 H HG23 . THR B 1 369 ? -19.336 36.907  34.820 1.00 12.63 ?  335  THR B HG23 1 
ATOM   10809 N N    . ASN B 1 370 ? -18.872 32.691  37.429 1.00 7.91  ?  336  ASN B N    1 
ATOM   10810 C CA   . ASN B 1 370 ? -18.855 31.291  37.827 1.00 8.67  ?  336  ASN B CA   1 
ATOM   10811 C C    . ASN B 1 370 ? -19.079 31.101  39.324 1.00 8.44  ?  336  ASN B C    1 
ATOM   10812 O O    . ASN B 1 370 ? -18.919 29.977  39.831 1.00 10.30 ?  336  ASN B O    1 
ATOM   10813 C CB   . ASN B 1 370 ? -17.580 30.590  37.359 1.00 9.27  ?  336  ASN B CB   1 
ATOM   10814 C CG   . ASN B 1 370 ? -17.725 29.076  37.328 1.00 10.42 ?  336  ASN B CG   1 
ATOM   10815 O OD1  . ASN B 1 370 ? -18.736 28.538  36.874 1.00 11.76 ?  336  ASN B OD1  1 
ATOM   10816 N ND2  . ASN B 1 370 ? -16.711 28.382  37.808 1.00 12.30 ?  336  ASN B ND2  1 
ATOM   10817 H H    . ASN B 1 370 ? -18.266 33.166  37.811 1.00 9.49  ?  336  ASN B H    1 
ATOM   10818 H HA   . ASN B 1 370 ? -19.586 30.842  37.374 1.00 10.40 ?  336  ASN B HA   1 
ATOM   10819 H HB2  . ASN B 1 370 ? -17.364 30.890  36.463 1.00 11.12 ?  336  ASN B HB2  1 
ATOM   10820 H HB3  . ASN B 1 370 ? -16.857 30.811  37.967 1.00 11.12 ?  336  ASN B HB3  1 
ATOM   10821 H HD21 . ASN B 1 370 ? -16.742 27.522  37.813 1.00 14.75 ?  336  ASN B HD21 1 
ATOM   10822 H HD22 . ASN B 1 370 ? -16.019 28.789  38.116 1.00 14.75 ?  336  ASN B HD22 1 
ATOM   10823 N N    . SER B 1 371 ? -19.466 32.146  40.036 1.00 8.01  ?  337  SER B N    1 
ATOM   10824 C CA   . SER B 1 371 ? -19.654 32.087  41.482 1.00 8.12  ?  337  SER B CA   1 
ATOM   10825 C C    . SER B 1 371 ? -21.123 32.046  41.864 1.00 8.94  ?  337  SER B C    1 
ATOM   10826 O O    . SER B 1 371 ? -21.885 32.953  41.499 1.00 10.14 ?  337  SER B O    1 
ATOM   10827 C CB   . SER B 1 371 ? -19.041 33.321  42.135 1.00 9.08  ?  337  SER B CB   1 
ATOM   10828 O OG   . SER B 1 371 ? -19.499 33.405  43.487 1.00 8.91  ?  337  SER B OG   1 
ATOM   10829 H H    . SER B 1 371 ? -19.631 32.920  39.699 1.00 9.61  ?  337  SER B H    1 
ATOM   10830 H HA   . SER B 1 371 ? -19.235 31.271  41.799 1.00 9.74  ?  337  SER B HA   1 
ATOM   10831 H HB2  . SER B 1 371 ? -18.074 33.245  42.126 1.00 10.89 ?  337  SER B HB2  1 
ATOM   10832 H HB3  . SER B 1 371 ? -19.316 34.114  41.650 1.00 10.89 ?  337  SER B HB3  1 
ATOM   10833 H HG   . SER B 1 371 ? -18.991 33.905  43.932 1.00 10.69 ?  337  SER B HG   1 
ATOM   10834 N N    . ALA B 1 372 ? -21.500 31.050  42.668 1.00 8.50  ?  338  ALA B N    1 
ATOM   10835 C CA   . ALA B 1 372 ? -22.874 30.945  43.130 1.00 9.11  ?  338  ALA B CA   1 
ATOM   10836 C C    . ALA B 1 372 ? -23.250 32.002  44.156 1.00 10.39 ?  338  ALA B C    1 
ATOM   10837 O O    . ALA B 1 372 ? -24.439 32.141  44.467 1.00 13.21 ?  338  ALA B O    1 
ATOM   10838 C CB   . ALA B 1 372 ? -23.126 29.550  43.713 1.00 13.85 ?  338  ALA B CB   1 
ATOM   10839 H H    . ALA B 1 372 ? -20.978 30.430  42.956 1.00 10.20 ?  338  ALA B H    1 
ATOM   10840 H HA   . ALA B 1 372 ? -23.457 31.063  42.364 1.00 10.94 ?  338  ALA B HA   1 
ATOM   10841 H HB1  . ALA B 1 372 ? -24.055 29.486  43.986 1.00 16.62 ?  338  ALA B HB1  1 
ATOM   10842 H HB2  . ALA B 1 372 ? -22.935 28.884  43.033 1.00 16.62 ?  338  ALA B HB2  1 
ATOM   10843 H HB3  . ALA B 1 372 ? -22.546 29.418  44.478 1.00 16.62 ?  338  ALA B HB3  1 
ATOM   10844 N N    . VAL B 1 373 ? -22.297 32.746  44.706 1.00 9.58  ?  339  VAL B N    1 
ATOM   10845 C CA   . VAL B 1 373 ? -22.593 33.780  45.689 1.00 10.51 ?  339  VAL B CA   1 
ATOM   10846 C C    . VAL B 1 373 ? -22.438 35.175  45.124 1.00 10.10 ?  339  VAL B C    1 
ATOM   10847 O O    . VAL B 1 373 ? -22.613 36.163  45.856 1.00 11.10 ?  339  VAL B O    1 
ATOM   10848 C CB   . VAL B 1 373 ? -21.788 33.600  46.995 1.00 11.00 ?  339  VAL B CB   1 
ATOM   10849 C CG1  . VAL B 1 373 ? -22.131 32.268  47.620 1.00 12.56 ?  339  VAL B CG1  1 
ATOM   10850 C CG2  . VAL B 1 373 ? -20.295 33.748  46.762 1.00 10.98 ?  339  VAL B CG2  1 
ATOM   10851 H H    . VAL B 1 373 ? -21.460 32.669  44.524 1.00 11.49 ?  339  VAL B H    1 
ATOM   10852 H HA   . VAL B 1 373 ? -23.525 33.688  45.941 1.00 12.62 ?  339  VAL B HA   1 
ATOM   10853 H HB   . VAL B 1 373 ? -22.033 34.303  47.617 1.00 13.20 ?  339  VAL B HB   1 
ATOM   10854 H HG11 . VAL B 1 373 ? -21.634 32.170  48.447 1.00 15.07 ?  339  VAL B HG11 1 
ATOM   10855 H HG12 . VAL B 1 373 ? -23.084 32.240  47.801 1.00 15.07 ?  339  VAL B HG12 1 
ATOM   10856 H HG13 . VAL B 1 373 ? -21.891 31.559  47.004 1.00 15.07 ?  339  VAL B HG13 1 
ATOM   10857 H HG21 . VAL B 1 373 ? -19.834 33.672  47.612 1.00 13.18 ?  339  VAL B HG21 1 
ATOM   10858 H HG22 . VAL B 1 373 ? -19.999 33.047  46.160 1.00 13.18 ?  339  VAL B HG22 1 
ATOM   10859 H HG23 . VAL B 1 373 ? -20.122 34.617  46.368 1.00 13.18 ?  339  VAL B HG23 1 
ATOM   10860 N N    . TRP B 1 374 ? -22.154 35.299  43.836 1.00 10.41 ?  340  TRP B N    1 
ATOM   10861 C CA   . TRP B 1 374 ? -22.068 36.610  43.216 1.00 11.13 ?  340  TRP B CA   1 
ATOM   10862 C C    . TRP B 1 374 ? -23.395 37.329  43.366 1.00 11.17 ?  340  TRP B C    1 
ATOM   10863 O O    . TRP B 1 374 ? -24.457 36.768  43.100 1.00 12.50 ?  340  TRP B O    1 
ATOM   10864 C CB   . TRP B 1 374 ? -21.732 36.426  41.744 1.00 11.28 ?  340  TRP B CB   1 
ATOM   10865 C CG   . TRP B 1 374 ? -21.631 37.685  40.931 1.00 12.06 ?  340  TRP B CG   1 
ATOM   10866 C CD1  . TRP B 1 374 ? -22.364 37.993  39.829 1.00 11.67 ?  340  TRP B CD1  1 
ATOM   10867 C CD2  . TRP B 1 374 ? -20.726 38.784  41.136 1.00 10.61 ?  340  TRP B CD2  1 
ATOM   10868 N NE1  . TRP B 1 374 ? -21.978 39.220  39.336 1.00 10.91 ?  340  TRP B NE1  1 
ATOM   10869 C CE2  . TRP B 1 374 ? -20.980 39.724  40.128 1.00 9.86  ?  340  TRP B CE2  1 
ATOM   10870 C CE3  . TRP B 1 374 ? -19.748 39.080  42.089 1.00 10.37 ?  340  TRP B CE3  1 
ATOM   10871 C CZ2  . TRP B 1 374 ? -20.275 40.918  40.034 1.00 10.50 ?  340  TRP B CZ2  1 
ATOM   10872 C CZ3  . TRP B 1 374 ? -19.051 40.272  41.989 1.00 10.89 ?  340  TRP B CZ3  1 
ATOM   10873 C CH2  . TRP B 1 374 ? -19.323 41.175  40.972 1.00 10.87 ?  340  TRP B CH2  1 
ATOM   10874 H H    . TRP B 1 374 ? -22.006 34.642  43.302 1.00 12.49 ?  340  TRP B H    1 
ATOM   10875 H HA   . TRP B 1 374 ? -21.378 37.148  43.634 1.00 13.35 ?  340  TRP B HA   1 
ATOM   10876 H HB2  . TRP B 1 374 ? -20.875 35.976  41.682 1.00 13.54 ?  340  TRP B HB2  1 
ATOM   10877 H HB3  . TRP B 1 374 ? -22.423 35.879  41.340 1.00 13.54 ?  340  TRP B HB3  1 
ATOM   10878 H HD1  . TRP B 1 374 ? -23.028 37.456  39.462 1.00 14.01 ?  340  TRP B HD1  1 
ATOM   10879 H HE1  . TRP B 1 374 ? -22.309 39.607  38.642 1.00 13.09 ?  340  TRP B HE1  1 
ATOM   10880 H HE3  . TRP B 1 374 ? -19.568 38.485  42.780 1.00 12.44 ?  340  TRP B HE3  1 
ATOM   10881 H HZ2  . TRP B 1 374 ? -20.449 41.524  39.350 1.00 12.60 ?  340  TRP B HZ2  1 
ATOM   10882 H HZ3  . TRP B 1 374 ? -18.391 40.471  42.613 1.00 13.07 ?  340  TRP B HZ3  1 
ATOM   10883 H HH2  . TRP B 1 374 ? -18.845 41.972  40.930 1.00 13.04 ?  340  TRP B HH2  1 
ATOM   10884 N N    . LEU B 1 375 ? -23.326 38.579  43.824 1.00 10.53 ?  341  LEU B N    1 
ATOM   10885 C CA   . LEU B 1 375 ? -24.467 39.462  44.056 1.00 12.03 ?  341  LEU B CA   1 
ATOM   10886 C C    . LEU B 1 375 ? -25.271 39.097  45.297 1.00 14.58 ?  341  LEU B C    1 
ATOM   10887 O O    . LEU B 1 375 ? -26.273 39.767  45.582 1.00 18.58 ?  341  LEU B O    1 
ATOM   10888 C CB   . LEU B 1 375 ? -25.401 39.582  42.840 1.00 13.27 ?  341  LEU B CB   1 
ATOM   10889 C CG   . LEU B 1 375 ? -24.761 40.183  41.593 1.00 13.95 ?  341  LEU B CG   1 
ATOM   10890 C CD1  . LEU B 1 375 ? -25.666 40.043  40.385 1.00 17.90 ?  341  LEU B CD1  1 
ATOM   10891 C CD2  . LEU B 1 375 ? -24.471 41.648  41.820 1.00 15.59 ?  341  LEU B CD2  1 
ATOM   10892 H H    . LEU B 1 375 ? -22.580 38.958  44.019 1.00 12.64 ?  341  LEU B H    1 
ATOM   10893 H HA   . LEU B 1 375 ? -24.109 40.350  44.214 1.00 14.43 ?  341  LEU B HA   1 
ATOM   10894 H HB2  . LEU B 1 375 ? -25.716 38.695  42.607 1.00 15.93 ?  341  LEU B HB2  1 
ATOM   10895 H HB3  . LEU B 1 375 ? -26.151 40.147  43.084 1.00 15.93 ?  341  LEU B HB3  1 
ATOM   10896 H HG   . LEU B 1 375 ? -23.935 39.707  41.415 1.00 16.74 ?  341  LEU B HG   1 
ATOM   10897 H HD11 . LEU B 1 375 ? -25.196 40.364  39.599 1.00 21.49 ?  341  LEU B HD11 1 
ATOM   10898 H HD12 . LEU B 1 375 ? -25.899 39.108  40.272 1.00 21.49 ?  341  LEU B HD12 1 
ATOM   10899 H HD13 . LEU B 1 375 ? -26.469 40.568  40.528 1.00 21.49 ?  341  LEU B HD13 1 
ATOM   10900 H HD21 . LEU B 1 375 ? -24.179 42.045  40.985 1.00 18.70 ?  341  LEU B HD21 1 
ATOM   10901 H HD22 . LEU B 1 375 ? -25.280 42.086  42.129 1.00 18.70 ?  341  LEU B HD22 1 
ATOM   10902 H HD23 . LEU B 1 375 ? -23.773 41.733  42.488 1.00 18.70 ?  341  LEU B HD23 1 
ATOM   10903 N N    . HIS B 1 376 ? -24.858 38.107  46.067 1.00 11.88 ?  342  HIS B N    1 
ATOM   10904 C CA   . HIS B 1 376 ? -25.670 37.615  47.164 1.00 11.02 ?  342  HIS B CA   1 
ATOM   10905 C C    . HIS B 1 376 ? -25.257 38.184  48.508 1.00 13.09 ?  342  HIS B C    1 
ATOM   10906 O O    . HIS B 1 376 ? -24.068 38.264  48.823 1.00 15.68 ?  342  HIS B O    1 
ATOM   10907 C CB   . HIS B 1 376 ? -25.599 36.093  47.268 1.00 12.82 ?  342  HIS B CB   1 
ATOM   10908 C CG   . HIS B 1 376 ? -26.512 35.536  48.313 1.00 12.55 ?  342  HIS B CG   1 
ATOM   10909 N ND1  . HIS B 1 376 ? -27.882 35.570  48.172 1.00 17.14 ?  342  HIS B ND1  1 
ATOM   10910 C CD2  . HIS B 1 376 ? -26.270 34.912  49.490 1.00 12.59 ?  342  HIS B CD2  1 
ATOM   10911 C CE1  . HIS B 1 376 ? -28.446 35.017  49.232 1.00 17.17 ?  342  HIS B CE1  1 
ATOM   10912 N NE2  . HIS B 1 376 ? -27.489 34.608  50.044 1.00 16.62 ?  342  HIS B NE2  1 
ATOM   10913 H H    . HIS B 1 376 ? -24.105 37.701  45.973 1.00 14.26 ?  342  HIS B H    1 
ATOM   10914 H HA   . HIS B 1 376 ? -26.577 37.903  46.981 1.00 13.22 ?  342  HIS B HA   1 
ATOM   10915 H HB2  . HIS B 1 376 ? -25.850 35.707  46.414 1.00 15.39 ?  342  HIS B HB2  1 
ATOM   10916 H HB3  . HIS B 1 376 ? -24.692 35.834  47.494 1.00 15.39 ?  342  HIS B HB3  1 
ATOM   10917 H HD1  . HIS B 1 376 ? -28.304 35.899  47.499 1.00 20.57 ?  342  HIS B HD1  1 
ATOM   10918 H HD2  . HIS B 1 376 ? -25.435 34.724  49.854 1.00 15.10 ?  342  HIS B HD2  1 
ATOM   10919 H HE1  . HIS B 1 376 ? -29.360 34.931  49.380 1.00 20.60 ?  342  HIS B HE1  1 
ATOM   10920 N N    . GLN B 1 377 ? -26.243 38.513  49.322 1.00 14.57 ?  343  GLN B N    1 
ATOM   10921 C CA   . GLN B 1 377 ? -26.016 38.924  50.703 1.00 13.16 ?  343  GLN B CA   1 
ATOM   10922 C C    . GLN B 1 377 ? -26.615 37.871  51.628 1.00 13.62 ?  343  GLN B C    1 
ATOM   10923 O O    . GLN B 1 377 ? -27.835 37.710  51.686 1.00 15.16 ?  343  GLN B O    1 
ATOM   10924 C CB   . GLN B 1 377 ? -26.644 40.293  50.958 1.00 18.82 ?  343  GLN B CB   1 
ATOM   10925 C CG   . GLN B 1 377 ? -26.166 40.970  52.233 1.00 32.08 ?  343  GLN B CG   1 
ATOM   10926 C CD   . GLN B 1 377 ? -25.900 42.448  52.037 1.00 40.18 ?  343  GLN B CD   1 
ATOM   10927 O OE1  . GLN B 1 377 ? -24.831 42.950  52.395 1.00 36.54 ?  343  GLN B OE1  1 
ATOM   10928 N NE2  . GLN B 1 377 ? -26.885 43.162  51.479 1.00 32.45 ?  343  GLN B NE2  1 
ATOM   10929 H H    . GLN B 1 377 ? -27.072 38.508  49.096 1.00 17.49 ?  343  GLN B H    1 
ATOM   10930 H HA   . GLN B 1 377 ? -25.062 38.975  50.875 1.00 15.79 ?  343  GLN B HA   1 
ATOM   10931 H HB2  . GLN B 1 377 ? -26.427 40.877  50.215 1.00 22.59 ?  343  GLN B HB2  1 
ATOM   10932 H HB3  . GLN B 1 377 ? -27.606 40.185  51.025 1.00 22.59 ?  343  GLN B HB3  1 
ATOM   10933 H HG2  . GLN B 1 377 ? -26.846 40.874  52.917 1.00 38.49 ?  343  GLN B HG2  1 
ATOM   10934 H HG3  . GLN B 1 377 ? -25.341 40.551  52.524 1.00 38.49 ?  343  GLN B HG3  1 
ATOM   10935 H HE21 . GLN B 1 377 ? -27.621 42.777  51.253 1.00 38.95 ?  343  GLN B HE21 1 
ATOM   10936 H HE22 . GLN B 1 377 ? -26.782 44.005  51.346 1.00 38.95 ?  343  GLN B HE22 1 
ATOM   10937 N N    . PHE B 1 378 ? -25.766 37.133  52.336 1.00 11.53 ?  344  PHE B N    1 
ATOM   10938 C CA   . PHE B 1 378 ? -26.270 36.244  53.377 1.00 10.49 ?  344  PHE B CA   1 
ATOM   10939 C C    . PHE B 1 378 ? -26.919 37.065  54.491 1.00 10.91 ?  344  PHE B C    1 
ATOM   10940 O O    . PHE B 1 378 ? -26.554 38.213  54.739 1.00 11.72 ?  344  PHE B O    1 
ATOM   10941 C CB   . PHE B 1 378 ? -25.122 35.400  53.939 1.00 11.75 ?  344  PHE B CB   1 
ATOM   10942 C CG   . PHE B 1 378 ? -24.652 34.335  52.990 1.00 13.26 ?  344  PHE B CG   1 
ATOM   10943 C CD1  . PHE B 1 378 ? -25.407 33.201  52.793 1.00 13.19 ?  344  PHE B CD1  1 
ATOM   10944 C CD2  . PHE B 1 378 ? -23.465 34.473  52.309 1.00 14.92 ?  344  PHE B CD2  1 
ATOM   10945 C CE1  . PHE B 1 378 ? -24.992 32.212  51.905 1.00 14.44 ?  344  PHE B CE1  1 
ATOM   10946 C CE2  . PHE B 1 378 ? -23.037 33.477  51.424 1.00 14.97 ?  344  PHE B CE2  1 
ATOM   10947 C CZ   . PHE B 1 378 ? -23.801 32.364  51.228 1.00 14.50 ?  344  PHE B CZ   1 
ATOM   10948 H H    . PHE B 1 378 ? -24.912 37.128  52.237 1.00 13.84 ?  344  PHE B H    1 
ATOM   10949 H HA   . PHE B 1 378 ? -26.938 35.642  53.012 1.00 12.59 ?  344  PHE B HA   1 
ATOM   10950 H HB2  . PHE B 1 378 ? -24.370 35.982  54.132 1.00 14.10 ?  344  PHE B HB2  1 
ATOM   10951 H HB3  . PHE B 1 378 ? -25.422 34.964  54.752 1.00 14.10 ?  344  PHE B HB3  1 
ATOM   10952 H HD1  . PHE B 1 378 ? -26.205 33.095  53.259 1.00 15.83 ?  344  PHE B HD1  1 
ATOM   10953 H HD2  . PHE B 1 378 ? -22.944 35.232  52.439 1.00 17.90 ?  344  PHE B HD2  1 
ATOM   10954 H HE1  . PHE B 1 378 ? -25.515 31.455  51.770 1.00 17.33 ?  344  PHE B HE1  1 
ATOM   10955 H HE2  . PHE B 1 378 ? -22.232 33.575  50.968 1.00 17.96 ?  344  PHE B HE2  1 
ATOM   10956 H HZ   . PHE B 1 378 ? -23.517 31.706  50.635 1.00 17.40 ?  344  PHE B HZ   1 
ATOM   10957 N N    . ASP B 1 379 ? -27.877 36.447  55.190 1.00 12.26 ?  345  ASP B N    1 
ATOM   10958 C CA   . ASP B 1 379 ? -28.547 37.142  56.287 1.00 13.84 ?  345  ASP B CA   1 
ATOM   10959 C C    . ASP B 1 379 ? -27.559 37.569  57.362 1.00 11.71 ?  345  ASP B C    1 
ATOM   10960 O O    . ASP B 1 379 ? -27.739 38.609  58.010 1.00 12.90 ?  345  ASP B O    1 
ATOM   10961 C CB   . ASP B 1 379 ? -29.636 36.256  56.906 1.00 16.61 ?  345  ASP B CB   1 
ATOM   10962 C CG   . ASP B 1 379 ? -30.774 35.949  55.933 1.00 24.97 ?  345  ASP B CG   1 
ATOM   10963 O OD1  . ASP B 1 379 ? -30.972 36.729  54.981 1.00 24.59 ?  345  ASP B OD1  1 
ATOM   10964 O OD2  . ASP B 1 379 ? -31.482 34.939  56.146 1.00 33.47 ?  345  ASP B OD2  1 
ATOM   10965 H H    . ASP B 1 379 ? -28.151 35.644  55.050 1.00 14.72 ?  345  ASP B H    1 
ATOM   10966 H HA   . ASP B 1 379 ? -28.975 37.934  55.927 1.00 16.61 ?  345  ASP B HA   1 
ATOM   10967 H HB2  . ASP B 1 379 ? -29.240 35.414  57.180 1.00 19.93 ?  345  ASP B HB2  1 
ATOM   10968 H HB3  . ASP B 1 379 ? -30.014 36.711  57.675 1.00 19.93 ?  345  ASP B HB3  1 
ATOM   10969 N N    . GLN B 1 380 ? -26.496 36.788  57.542 1.00 11.31 ?  346  GLN B N    1 
ATOM   10970 C CA   . GLN B 1 380 ? -25.467 37.099  58.521 1.00 10.92 ?  346  GLN B CA   1 
ATOM   10971 C C    . GLN B 1 380 ? -24.728 38.394  58.211 1.00 11.38 ?  346  GLN B C    1 
ATOM   10972 O O    . GLN B 1 380 ? -24.005 38.908  59.078 1.00 13.18 ?  346  GLN B O    1 
ATOM   10973 C CB   . GLN B 1 380 ? -24.454 35.954  58.577 1.00 11.89 ?  346  GLN B CB   1 
ATOM   10974 C CG   . GLN B 1 380 ? -24.999 34.625  59.081 1.00 10.60 ?  346  GLN B CG   1 
ATOM   10975 C CD   . GLN B 1 380 ? -25.583 33.736  58.001 1.00 11.57 ?  346  GLN B CD   1 
ATOM   10976 O OE1  . GLN B 1 380 ? -26.082 34.203  56.975 1.00 12.28 ?  346  GLN B OE1  1 
ATOM   10977 N NE2  . GLN B 1 380 ? -25.563 32.444  58.244 1.00 11.26 ?  346  GLN B NE2  1 
ATOM   10978 H H    . GLN B 1 380 ? -26.347 36.064  57.103 1.00 13.58 ?  346  GLN B H    1 
ATOM   10979 H HA   . GLN B 1 380 ? -25.892 37.196  59.388 1.00 13.10 ?  346  GLN B HA   1 
ATOM   10980 H HB2  . GLN B 1 380 ? -24.112 35.805  57.681 1.00 14.27 ?  346  GLN B HB2  1 
ATOM   10981 H HB3  . GLN B 1 380 ? -23.731 36.214  59.169 1.00 14.27 ?  346  GLN B HB3  1 
ATOM   10982 H HG2  . GLN B 1 380 ? -24.276 34.135  59.505 1.00 12.72 ?  346  GLN B HG2  1 
ATOM   10983 H HG3  . GLN B 1 380 ? -25.701 34.803  59.726 1.00 12.72 ?  346  GLN B HG3  1 
ATOM   10984 H HE21 . GLN B 1 380 ? -25.231 32.150  58.981 1.00 13.51 ?  346  GLN B HE21 1 
ATOM   10985 H HE22 . GLN B 1 380 ? -25.881 31.893  57.666 1.00 13.51 ?  346  GLN B HE22 1 
ATOM   10986 N N    . TYR B 1 381 ? -24.827 38.905  56.981 1.00 10.63 ?  347  TYR B N    1 
ATOM   10987 C CA   . TYR B 1 381 ? -24.193 40.163  56.612 1.00 10.36 ?  347  TYR B CA   1 
ATOM   10988 C C    . TYR B 1 381 ? -25.072 41.370  56.917 1.00 11.77 ?  347  TYR B C    1 
ATOM   10989 O O    . TYR B 1 381 ? -24.590 42.511  56.847 1.00 13.23 ?  347  TYR B O    1 
ATOM   10990 C CB   . TYR B 1 381 ? -23.849 40.191  55.114 1.00 11.58 ?  347  TYR B CB   1 
ATOM   10991 C CG   . TYR B 1 381 ? -22.930 39.112  54.589 1.00 10.78 ?  347  TYR B CG   1 
ATOM   10992 C CD1  . TYR B 1 381 ? -22.223 38.268  55.428 1.00 12.68 ?  347  TYR B CD1  1 
ATOM   10993 C CD2  . TYR B 1 381 ? -22.765 38.955  53.224 1.00 10.44 ?  347  TYR B CD2  1 
ATOM   10994 C CE1  . TYR B 1 381 ? -21.383 37.293  54.902 1.00 14.60 ?  347  TYR B CE1  1 
ATOM   10995 C CE2  . TYR B 1 381 ? -21.928 37.986  52.699 1.00 13.88 ?  347  TYR B CE2  1 
ATOM   10996 C CZ   . TYR B 1 381 ? -21.257 37.150  53.535 1.00 15.86 ?  347  TYR B CZ   1 
ATOM   10997 O OH   . TYR B 1 381 ? -20.425 36.165  52.995 1.00 18.87 ?  347  TYR B OH   1 
ATOM   10998 H H    . TYR B 1 381 ? -25.261 38.533  56.338 1.00 12.75 ?  347  TYR B H    1 
ATOM   10999 H HA   . TYR B 1 381 ? -23.364 40.235  57.110 1.00 12.43 ?  347  TYR B HA   1 
ATOM   11000 H HB2  . TYR B 1 381 ? -24.679 40.118  54.617 1.00 13.90 ?  347  TYR B HB2  1 
ATOM   11001 H HB3  . TYR B 1 381 ? -23.422 41.040  54.924 1.00 13.90 ?  347  TYR B HB3  1 
ATOM   11002 H HD1  . TYR B 1 381 ? -22.310 38.354  56.350 1.00 15.22 ?  347  TYR B HD1  1 
ATOM   11003 H HD2  . TYR B 1 381 ? -23.228 39.515  52.644 1.00 12.53 ?  347  TYR B HD2  1 
ATOM   11004 H HE1  . TYR B 1 381 ? -20.905 36.736  55.473 1.00 17.52 ?  347  TYR B HE1  1 
ATOM   11005 H HE2  . TYR B 1 381 ? -21.826 37.907  51.778 1.00 16.66 ?  347  TYR B HE2  1 
ATOM   11006 H HH   . TYR B 1 381 ? -20.496 36.155  52.158 1.00 22.64 ?  347  TYR B HH   1 
ATOM   11007 N N    . LYS B 1 382 ? -26.357 41.146  57.203 1.00 13.19 ?  348  LYS B N    1 
ATOM   11008 C CA   . LYS B 1 382 ? -27.307 42.227  57.401 1.00 14.31 ?  348  LYS B CA   1 
ATOM   11009 C C    . LYS B 1 382 ? -27.632 42.460  58.862 1.00 14.00 ?  348  LYS B C    1 
ATOM   11010 O O    . LYS B 1 382 ? -28.093 43.552  59.211 1.00 16.46 ?  348  LYS B O    1 
ATOM   11011 C CB   . LYS B 1 382 ? -28.618 41.928  56.670 1.00 18.55 ?  348  LYS B CB   1 
ATOM   11012 C CG   . LYS B 1 382 ? -28.443 41.571  55.208 1.00 24.31 ?  348  LYS B CG   1 
ATOM   11013 C CD   . LYS B 1 382 ? -29.751 41.754  54.456 1.00 32.33 ?  348  LYS B CD   1 
ATOM   11014 C CE   . LYS B 1 382 ? -30.511 40.451  54.326 1.00 36.59 ?  348  LYS B CE   1 
ATOM   11015 N NZ   . LYS B 1 382 ? -30.679 40.049  52.900 1.00 38.37 ?  348  LYS B NZ   1 
ATOM   11016 H H    . LYS B 1 382 ? -26.702 40.363  57.286 1.00 15.83 ?  348  LYS B H    1 
ATOM   11017 H HA   . LYS B 1 382 ? -26.930 43.039  57.030 1.00 17.17 ?  348  LYS B HA   1 
ATOM   11018 H HB2  . LYS B 1 382 ? -29.053 41.179  57.106 1.00 22.26 ?  348  LYS B HB2  1 
ATOM   11019 H HB3  . LYS B 1 382 ? -29.185 42.713  56.715 1.00 22.26 ?  348  LYS B HB3  1 
ATOM   11020 H HG2  . LYS B 1 382 ? -27.773 42.149  54.810 1.00 29.17 ?  348  LYS B HG2  1 
ATOM   11021 H HG3  . LYS B 1 382 ? -28.169 40.643  55.130 1.00 29.17 ?  348  LYS B HG3  1 
ATOM   11022 H HD2  . LYS B 1 382 ? -30.310 42.386  54.935 1.00 38.80 ?  348  LYS B HD2  1 
ATOM   11023 H HD3  . LYS B 1 382 ? -29.564 42.087  53.564 1.00 38.80 ?  348  LYS B HD3  1 
ATOM   11024 H HE2  . LYS B 1 382 ? -30.024 39.749  54.784 1.00 43.90 ?  348  LYS B HE2  1 
ATOM   11025 H HE3  . LYS B 1 382 ? -31.392 40.554  54.718 1.00 43.90 ?  348  LYS B HE3  1 
ATOM   11026 H HZ1  . LYS B 1 382 ? -31.135 39.286  52.851 1.00 46.05 ?  348  LYS B HZ1  1 
ATOM   11027 H HZ2  . LYS B 1 382 ? -31.123 40.680  52.456 1.00 46.05 ?  348  LYS B HZ2  1 
ATOM   11028 H HZ3  . LYS B 1 382 ? -29.883 39.935  52.520 1.00 46.05 ?  348  LYS B HZ3  1 
ATOM   11029 N N    . LYS B 1 383 ? -27.396 41.473  59.707 1.00 13.70 ?  349  LYS B N    1 
ATOM   11030 C CA   . LYS B 1 383 ? -27.767 41.577  61.112 1.00 13.53 ?  349  LYS B CA   1 
ATOM   11031 C C    . LYS B 1 383 ? -26.810 42.495  61.860 1.00 13.43 ?  349  LYS B C    1 
ATOM   11032 O O    . LYS B 1 383 ? -25.640 42.645  61.502 1.00 13.15 ?  349  LYS B O    1 
ATOM   11033 C CB   . LYS B 1 383 ? -27.782 40.191  61.749 1.00 14.35 ?  349  LYS B CB   1 
ATOM   11034 C CG   . LYS B 1 383 ? -28.973 39.333  61.297 1.00 14.18 ?  349  LYS B CG   1 
ATOM   11035 C CD   . LYS B 1 383 ? -28.912 37.898  61.790 1.00 14.62 ?  349  LYS B CD   1 
ATOM   11036 C CE   . LYS B 1 383 ? -30.128 37.127  61.307 1.00 17.37 ?  349  LYS B CE   1 
ATOM   11037 N NZ   . LYS B 1 383 ? -30.193 35.765  61.879 1.00 19.32 ?  349  LYS B NZ   1 
ATOM   11038 H H    . LYS B 1 383 ? -27.021 40.728  59.495 1.00 16.44 ?  349  LYS B H    1 
ATOM   11039 H HA   . LYS B 1 383 ? -28.657 41.956  61.190 1.00 16.24 ?  349  LYS B HA   1 
ATOM   11040 H HB2  . LYS B 1 383 ? -26.967 39.724  61.505 1.00 17.22 ?  349  LYS B HB2  1 
ATOM   11041 H HB3  . LYS B 1 383 ? -27.832 40.288  62.713 1.00 17.22 ?  349  LYS B HB3  1 
ATOM   11042 H HG2  . LYS B 1 383 ? -29.790 39.729  61.637 1.00 17.02 ?  349  LYS B HG2  1 
ATOM   11043 H HG3  . LYS B 1 383 ? -28.993 39.312  60.327 1.00 17.02 ?  349  LYS B HG3  1 
ATOM   11044 H HD2  . LYS B 1 383 ? -28.114 37.468  61.445 1.00 17.54 ?  349  LYS B HD2  1 
ATOM   11045 H HD3  . LYS B 1 383 ? -28.902 37.887  62.760 1.00 17.54 ?  349  LYS B HD3  1 
ATOM   11046 H HE2  . LYS B 1 383 ? -30.932 37.602  61.570 1.00 20.84 ?  349  LYS B HE2  1 
ATOM   11047 H HE3  . LYS B 1 383 ? -30.091 37.047  60.341 1.00 20.84 ?  349  LYS B HE3  1 
ATOM   11048 H HZ1  . LYS B 1 383 ? -30.942 35.361  61.619 1.00 23.18 ?  349  LYS B HZ1  1 
ATOM   11049 H HZ2  . LYS B 1 383 ? -29.495 35.286  61.602 1.00 23.18 ?  349  LYS B HZ2  1 
ATOM   11050 H HZ3  . LYS B 1 383 ? -30.180 35.807  62.767 1.00 23.18 ?  349  LYS B HZ3  1 
ATOM   11051 N N    . ALA B 1 384 ? -27.330 43.152  62.895 1.00 14.11 ?  350  ALA B N    1 
ATOM   11052 C CA   . ALA B 1 384 ? -26.507 44.046  63.683 1.00 12.88 ?  350  ALA B CA   1 
ATOM   11053 C C    . ALA B 1 384 ? -25.387 43.263  64.345 1.00 11.92 ?  350  ALA B C    1 
ATOM   11054 O O    . ALA B 1 384 ? -25.616 42.219  64.960 1.00 13.92 ?  350  ALA B O    1 
ATOM   11055 C CB   . ALA B 1 384 ? -27.355 44.746  64.745 1.00 15.95 ?  350  ALA B CB   1 
ATOM   11056 H H    . ALA B 1 384 ? -28.148 43.095  63.153 1.00 16.93 ?  350  ALA B H    1 
ATOM   11057 H HA   . ALA B 1 384 ? -26.121 44.726  63.109 1.00 15.45 ?  350  ALA B HA   1 
ATOM   11058 H HB1  . ALA B 1 384 ? -26.801 45.385  65.222 1.00 19.14 ?  350  ALA B HB1  1 
ATOM   11059 H HB2  . ALA B 1 384 ? -28.090 45.206  64.310 1.00 19.14 ?  350  ALA B HB2  1 
ATOM   11060 H HB3  . ALA B 1 384 ? -27.699 44.082  65.363 1.00 19.14 ?  350  ALA B HB3  1 
ATOM   11061 N N    . LEU B 1 385 ? -24.164 43.768  64.206 1.00 12.27 ?  351  LEU B N    1 
ATOM   11062 C CA   . LEU B 1 385 ? -22.979 43.134  64.770 1.00 13.63 ?  351  LEU B CA   1 
ATOM   11063 C C    . LEU B 1 385 ? -22.496 43.929  65.977 1.00 13.43 ?  351  LEU B C    1 
ATOM   11064 O O    . LEU B 1 385 ? -22.571 43.435  67.108 1.00 15.47 ?  351  LEU B O    1 
ATOM   11065 C CB   . LEU B 1 385 ? -21.906 43.027  63.680 1.00 12.06 ?  351  LEU B CB   1 
ATOM   11066 C CG   . LEU B 1 385 ? -20.510 42.600  64.112 1.00 11.69 ?  351  LEU B CG   1 
ATOM   11067 C CD1  . LEU B 1 385 ? -20.460 41.241  64.745 1.00 12.58 ?  351  LEU B CD1  1 
ATOM   11068 C CD2  . LEU B 1 385 ? -19.544 42.651  62.900 1.00 11.97 ?  351  LEU B CD2  1 
ATOM   11069 H H    . LEU B 1 385 ? -23.993 44.495  63.779 1.00 14.72 ?  351  LEU B H    1 
ATOM   11070 H HA   . LEU B 1 385 ? -23.183 42.238  65.080 1.00 16.35 ?  351  LEU B HA   1 
ATOM   11071 H HB2  . LEU B 1 385 ? -22.210 42.377  63.028 1.00 14.47 ?  351  LEU B HB2  1 
ATOM   11072 H HB3  . LEU B 1 385 ? -21.817 43.899  63.264 1.00 14.47 ?  351  LEU B HB3  1 
ATOM   11073 H HG   . LEU B 1 385 ? -20.223 43.226  64.796 1.00 14.02 ?  351  LEU B HG   1 
ATOM   11074 H HD11 . LEU B 1 385 ? -19.545 41.044  64.997 1.00 15.09 ?  351  LEU B HD11 1 
ATOM   11075 H HD12 . LEU B 1 385 ? -21.028 41.238  65.531 1.00 15.09 ?  351  LEU B HD12 1 
ATOM   11076 H HD13 . LEU B 1 385 ? -20.776 40.584  64.106 1.00 15.09 ?  351  LEU B HD13 1 
ATOM   11077 H HD21 . LEU B 1 385 ? -18.644 42.457  63.205 1.00 14.36 ?  351  LEU B HD21 1 
ATOM   11078 H HD22 . LEU B 1 385 ? -19.822 41.991  62.247 1.00 14.36 ?  351  LEU B HD22 1 
ATOM   11079 H HD23 . LEU B 1 385 ? -19.576 43.538  62.508 1.00 14.36 ?  351  LEU B HD23 1 
ATOM   11080 N N    . GLY B 1 386 ? -22.038 45.156  65.774 1.00 12.12 ?  352  GLY B N    1 
ATOM   11081 C CA   . GLY B 1 386 ? -21.569 45.985  66.863 1.00 13.62 ?  352  GLY B CA   1 
ATOM   11082 C C    . GLY B 1 386 ? -20.109 45.739  67.190 1.00 13.40 ?  352  GLY B C    1 
ATOM   11083 O O    . GLY B 1 386 ? -19.500 44.758  66.773 1.00 12.99 ?  352  GLY B O    1 
ATOM   11084 H H    . GLY B 1 386 ? -21.989 45.533  65.002 1.00 14.54 ?  352  GLY B H    1 
ATOM   11085 H HA2  . GLY B 1 386 ? -21.676 46.919  66.624 1.00 16.34 ?  352  GLY B HA2  1 
ATOM   11086 H HA3  . GLY B 1 386 ? -22.096 45.800  67.656 1.00 16.34 ?  352  GLY B HA3  1 
ATOM   11087 N N    . ALA B 1 387 ? -19.542 46.670  67.948 1.00 14.46 ?  353  ALA B N    1 
ATOM   11088 C CA   . ALA B 1 387 ? -18.132 46.608  68.265 1.00 15.75 ?  353  ALA B CA   1 
ATOM   11089 C C    . ALA B 1 387 ? -17.834 45.456  69.224 1.00 13.36 ?  353  ALA B C    1 
ATOM   11090 O O    . ALA B 1 387 ? -18.668 45.085  70.059 1.00 14.85 ?  353  ALA B O    1 
ATOM   11091 C CB   . ALA B 1 387 ? -17.670 47.918  68.897 1.00 18.39 ?  353  ALA B CB   1 
ATOM   11092 H H    . ALA B 1 387 ? -19.955 47.343  68.288 1.00 17.35 ?  353  ALA B H    1 
ATOM   11093 H HA   . ALA B 1 387 ? -17.633 46.459  67.446 1.00 18.90 ?  353  ALA B HA   1 
ATOM   11094 H HB1  . ALA B 1 387 ? -16.714 47.872  69.057 1.00 22.07 ?  353  ALA B HB1  1 
ATOM   11095 H HB2  . ALA B 1 387 ? -17.869 48.649  68.291 1.00 22.07 ?  353  ALA B HB2  1 
ATOM   11096 H HB3  . ALA B 1 387 ? -18.139 48.047  69.736 1.00 22.07 ?  353  ALA B HB3  1 
ATOM   11097 N N    . PRO B 1 388 ? -16.636 44.892  69.146 1.00 13.86 ?  354  PRO B N    1 
ATOM   11098 C CA   . PRO B 1 388 ? -16.252 43.857  70.109 1.00 14.18 ?  354  PRO B CA   1 
ATOM   11099 C C    . PRO B 1 388 ? -16.195 44.447  71.506 1.00 16.16 ?  354  PRO B C    1 
ATOM   11100 O O    . PRO B 1 388 ? -15.778 45.591  71.705 1.00 20.13 ?  354  PRO B O    1 
ATOM   11101 C CB   . PRO B 1 388 ? -14.861 43.408  69.635 1.00 19.68 ?  354  PRO B CB   1 
ATOM   11102 C CG   . PRO B 1 388 ? -14.394 44.476  68.679 1.00 16.85 ?  354  PRO B CG   1 
ATOM   11103 C CD   . PRO B 1 388 ? -15.597 45.155  68.134 1.00 15.79 ?  354  PRO B CD   1 
ATOM   11104 H HA   . PRO B 1 388 ? -16.859 43.101  70.075 1.00 17.02 ?  354  PRO B HA   1 
ATOM   11105 H HB2  . PRO B 1 388 ? -14.263 43.339  70.396 1.00 23.61 ?  354  PRO B HB2  1 
ATOM   11106 H HB3  . PRO B 1 388 ? -14.928 42.550  69.188 1.00 23.61 ?  354  PRO B HB3  1 
ATOM   11107 H HG2  . PRO B 1 388 ? -13.837 45.111  69.157 1.00 20.22 ?  354  PRO B HG2  1 
ATOM   11108 H HG3  . PRO B 1 388 ? -13.886 44.064  67.963 1.00 20.22 ?  354  PRO B HG3  1 
ATOM   11109 H HD2  . PRO B 1 388 ? -15.441 46.108  68.040 1.00 18.94 ?  354  PRO B HD2  1 
ATOM   11110 H HD3  . PRO B 1 388 ? -15.848 44.774  67.277 1.00 18.94 ?  354  PRO B HD3  1 
ATOM   11111 N N    . LEU B 1 389 ? -16.638 43.662  72.473 1.00 16.57 ?  355  LEU B N    1 
ATOM   11112 C CA   . LEU B 1 389 ? -16.563 44.040  73.878 1.00 19.60 ?  355  LEU B CA   1 
ATOM   11113 C C    . LEU B 1 389 ? -15.349 43.435  74.567 1.00 24.78 ?  355  LEU B C    1 
ATOM   11114 O O    . LEU B 1 389 ? -15.088 43.759  75.728 1.00 22.30 ?  355  LEU B O    1 
ATOM   11115 C CB   . LEU B 1 389 ? -17.877 43.673  74.583 1.00 26.30 ?  355  LEU B CB   1 
ATOM   11116 C CG   . LEU B 1 389 ? -19.077 44.337  73.890 1.00 28.88 ?  355  LEU B CG   1 
ATOM   11117 C CD1  . LEU B 1 389 ? -20.406 43.970  74.517 1.00 32.65 ?  355  LEU B CD1  1 
ATOM   11118 C CD2  . LEU B 1 389 ? -18.936 45.858  73.871 1.00 38.32 ?  355  LEU B CD2  1 
ATOM   11119 H H    . LEU B 1 389 ? -16.994 42.890  72.340 1.00 19.89 ?  355  LEU B H    1 
ATOM   11120 H HA   . LEU B 1 389 ? -16.474 45.002  73.965 1.00 23.52 ?  355  LEU B HA   1 
ATOM   11121 H HB2  . LEU B 1 389 ? -17.999 42.711  74.556 1.00 31.56 ?  355  LEU B HB2  1 
ATOM   11122 H HB3  . LEU B 1 389 ? -17.845 43.978  75.503 1.00 31.56 ?  355  LEU B HB3  1 
ATOM   11123 H HG   . LEU B 1 389 ? -19.082 44.000  72.980 1.00 34.65 ?  355  LEU B HG   1 
ATOM   11124 H HD11 . LEU B 1 389 ? -21.111 44.471  74.079 1.00 39.18 ?  355  LEU B HD11 1 
ATOM   11125 H HD12 . LEU B 1 389 ? -20.557 43.019  74.404 1.00 39.18 ?  355  LEU B HD12 1 
ATOM   11126 H HD13 . LEU B 1 389 ? -20.381 44.191  75.461 1.00 39.18 ?  355  LEU B HD13 1 
ATOM   11127 H HD21 . LEU B 1 389 ? -19.728 46.244  73.465 1.00 45.99 ?  355  LEU B HD21 1 
ATOM   11128 H HD22 . LEU B 1 389 ? -18.841 46.178  74.781 1.00 45.99 ?  355  LEU B HD22 1 
ATOM   11129 H HD23 . LEU B 1 389 ? -18.151 46.096  73.353 1.00 45.99 ?  355  LEU B HD23 1 
ATOM   11130 N N    . GLY B 1 390 ? -14.567 42.629  73.856 1.00 22.87 ?  356  GLY B N    1 
ATOM   11131 C CA   . GLY B 1 390 ? -13.280 42.164  74.350 1.00 21.20 ?  356  GLY B CA   1 
ATOM   11132 C C    . GLY B 1 390 ? -12.637 41.278  73.308 1.00 25.76 ?  356  GLY B C    1 
ATOM   11133 O O    . GLY B 1 390 ? -13.273 40.878  72.328 1.00 22.60 ?  356  GLY B O    1 
ATOM   11134 H H    . GLY B 1 390 ? -14.763 42.333  73.073 1.00 27.45 ?  356  GLY B H    1 
ATOM   11135 H HA2  . GLY B 1 390 ? -12.698 42.919  74.529 1.00 25.44 ?  356  GLY B HA2  1 
ATOM   11136 H HA3  . GLY B 1 390 ? -13.400 41.657  75.169 1.00 25.44 ?  356  GLY B HA3  1 
ATOM   11137 N N    . LYS B 1 391 ? -11.352 40.992  73.521 1.00 20.98 ?  357  LYS B N    1 
ATOM   11138 C CA   . LYS B 1 391 ? -10.646 40.059  72.657 1.00 18.68 ?  357  LYS B CA   1 
ATOM   11139 C C    . LYS B 1 391 ? -11.261 38.663  72.777 1.00 17.67 ?  357  LYS B C    1 
ATOM   11140 O O    . LYS B 1 391 ? -11.955 38.327  73.739 1.00 20.46 ?  357  LYS B O    1 
ATOM   11141 C CB   . LYS B 1 391 ? -9.159  40.004  73.011 1.00 27.79 ?  357  LYS B CB   1 
ATOM   11142 C CG   . LYS B 1 391 ? -8.366  41.277  72.657 1.00 29.05 ?  357  LYS B CG   1 
ATOM   11143 C CD   . LYS B 1 391 ? -8.729  41.918  71.292 1.00 24.16 ?  357  LYS B CD   1 
ATOM   11144 C CE   . LYS B 1 391 ? -7.740  43.018  70.927 1.00 37.48 ?  357  LYS B CE   1 
ATOM   11145 N NZ   . LYS B 1 391 ? -6.927  43.499  72.090 1.00 36.65 ?  357  LYS B NZ   1 
ATOM   11146 H H    . LYS B 1 391 ? -10.874 41.324  74.154 1.00 25.17 ?  357  LYS B H    1 
ATOM   11147 H HA   . LYS B 1 391 ? -10.719 40.355  71.736 1.00 22.41 ?  357  LYS B HA   1 
ATOM   11148 H HB2  . LYS B 1 391 ? -9.075  39.864  73.967 1.00 33.35 ?  357  LYS B HB2  1 
ATOM   11149 H HB3  . LYS B 1 391 ? -8.754  39.265  72.531 1.00 33.35 ?  357  LYS B HB3  1 
ATOM   11150 H HG2  . LYS B 1 391 ? -8.532  41.943  73.342 1.00 34.86 ?  357  LYS B HG2  1 
ATOM   11151 H HG3  . LYS B 1 391 ? -7.423  41.055  72.631 1.00 34.86 ?  357  LYS B HG3  1 
ATOM   11152 H HD2  . LYS B 1 391 ? -8.703  41.240  70.599 1.00 28.99 ?  357  LYS B HD2  1 
ATOM   11153 H HD3  . LYS B 1 391 ? -9.616  42.307  71.342 1.00 28.99 ?  357  LYS B HD3  1 
ATOM   11154 H HE2  . LYS B 1 391 ? -7.127  42.679  70.256 1.00 44.97 ?  357  LYS B HE2  1 
ATOM   11155 H HE3  . LYS B 1 391 ? -8.231  43.777  70.574 1.00 44.97 ?  357  LYS B HE3  1 
ATOM   11156 H HZ1  . LYS B 1 391 ? -6.404  44.174  71.838 1.00 43.97 ?  357  LYS B HZ1  1 
ATOM   11157 H HZ2  . LYS B 1 391 ? -7.464  43.778  72.743 1.00 43.97 ?  357  LYS B HZ2  1 
ATOM   11158 H HZ3  . LYS B 1 391 ? -6.416  42.838  72.399 1.00 43.97 ?  357  LYS B HZ3  1 
ATOM   11159 N N    . ALA B 1 392 ? -11.030 37.861  71.756 1.00 16.56 ?  358  ALA B N    1 
ATOM   11160 C CA   . ALA B 1 392 ? -11.461 36.480  71.814 1.00 13.49 ?  358  ALA B CA   1 
ATOM   11161 C C    . ALA B 1 392 ? -10.756 35.757  72.953 1.00 14.80 ?  358  ALA B C    1 
ATOM   11162 O O    . ALA B 1 392 ? -9.608  36.056  73.288 1.00 18.12 ?  358  ALA B O    1 
ATOM   11163 C CB   . ALA B 1 392 ? -11.141 35.785  70.498 1.00 16.74 ?  358  ALA B CB   1 
ATOM   11164 H H    . ALA B 1 392 ? -10.632 38.087  71.028 1.00 19.87 ?  358  ALA B H    1 
ATOM   11165 H HA   . ALA B 1 392 ? -12.418 36.440  71.965 1.00 16.19 ?  358  ALA B HA   1 
ATOM   11166 H HB1  . ALA B 1 392 ? -11.427 34.860  70.551 1.00 20.09 ?  358  ALA B HB1  1 
ATOM   11167 H HB2  . ALA B 1 392 ? -11.611 36.237  69.780 1.00 20.09 ?  358  ALA B HB2  1 
ATOM   11168 H HB3  . ALA B 1 392 ? -10.184 35.827  70.344 1.00 20.09 ?  358  ALA B HB3  1 
ATOM   11169 N N    . ILE B 1 393 ? -11.463 34.802  73.547 1.00 14.34 ?  359  ILE B N    1 
ATOM   11170 C CA   . ILE B 1 393 ? -10.917 33.934  74.581 1.00 17.80 ?  359  ILE B CA   1 
ATOM   11171 C C    . ILE B 1 393 ? -10.780 32.536  73.997 1.00 14.40 ?  359  ILE B C    1 
ATOM   11172 O O    . ILE B 1 393 ? -11.744 31.982  73.455 1.00 14.54 ?  359  ILE B O    1 
ATOM   11173 C CB   . ILE B 1 393 ? -11.835 33.915  75.811 1.00 17.99 ?  359  ILE B CB   1 
ATOM   11174 C CG1  . ILE B 1 393 ? -11.858 35.301  76.462 1.00 26.05 ?  359  ILE B CG1  1 
ATOM   11175 C CG2  . ILE B 1 393 ? -11.350 32.884  76.833 1.00 22.45 ?  359  ILE B CG2  1 
ATOM   11176 C CD1  . ILE B 1 393 ? -13.029 35.512  77.402 1.00 33.12 ?  359  ILE B CD1  1 
ATOM   11177 H H    . ILE B 1 393 ? -12.286 34.634  73.362 1.00 17.21 ?  359  ILE B H    1 
ATOM   11178 H HA   . ILE B 1 393 ? -10.038 34.247  74.845 1.00 21.36 ?  359  ILE B HA   1 
ATOM   11179 H HB   . ILE B 1 393 ? -12.728 33.674  75.520 1.00 21.59 ?  359  ILE B HB   1 
ATOM   11180 H HG12 . ILE B 1 393 ? -11.042 35.420  76.973 1.00 31.26 ?  359  ILE B HG12 1 
ATOM   11181 H HG13 . ILE B 1 393 ? -11.913 35.973  75.764 1.00 31.26 ?  359  ILE B HG13 1 
ATOM   11182 H HG21 . ILE B 1 393 ? -11.931 32.912  77.610 1.00 26.94 ?  359  ILE B HG21 1 
ATOM   11183 H HG22 . ILE B 1 393 ? -11.380 32.002  76.430 1.00 26.94 ?  359  ILE B HG22 1 
ATOM   11184 H HG23 . ILE B 1 393 ? -10.441 33.099  77.092 1.00 26.94 ?  359  ILE B HG23 1 
ATOM   11185 H HD11 . ILE B 1 393 ? -12.975 36.405  77.778 1.00 39.74 ?  359  ILE B HD11 1 
ATOM   11186 H HD12 . ILE B 1 393 ? -13.856 35.412  76.905 1.00 39.74 ?  359  ILE B HD12 1 
ATOM   11187 H HD13 . ILE B 1 393 ? -12.987 34.852  78.112 1.00 39.74 ?  359  ILE B HD13 1 
ATOM   11188 N N    . LYS B 1 394 ? -9.593  31.959  74.125 1.00 13.71 ?  360  LYS B N    1 
ATOM   11189 C CA   . LYS B 1 394 ? -9.296  30.620  73.640 1.00 11.37 ?  360  LYS B CA   1 
ATOM   11190 C C    . LYS B 1 394 ? -9.270  29.634  74.799 1.00 15.09 ?  360  LYS B C    1 
ATOM   11191 O O    . LYS B 1 394 ? -8.486  29.805  75.741 1.00 19.19 ?  360  LYS B O    1 
ATOM   11192 C CB   . LYS B 1 394 ? -7.932  30.603  72.951 1.00 16.23 ?  360  LYS B CB   1 
ATOM   11193 C CG   . LYS B 1 394 ? -7.519  29.284  72.390 1.00 14.31 ?  360  LYS B CG   1 
ATOM   11194 C CD   . LYS B 1 394 ? -6.104  29.384  71.801 1.00 18.65 ?  360  LYS B CD   1 
ATOM   11195 C CE   . LYS B 1 394 ? -5.675  28.102  71.127 1.00 17.84 ?  360  LYS B CE   1 
ATOM   11196 N NZ   . LYS B 1 394 ? -5.584  26.942  72.055 1.00 15.92 ?  360  LYS B NZ   1 
ATOM   11197 H H    . LYS B 1 394 ? -8.920  32.337  74.504 1.00 16.46 ?  360  LYS B H    1 
ATOM   11198 H HA   . LYS B 1 394 ? -9.994  30.355  73.021 1.00 13.64 ?  360  LYS B HA   1 
ATOM   11199 H HB2  . LYS B 1 394 ? -7.952  31.236  72.217 1.00 19.47 ?  360  LYS B HB2  1 
ATOM   11200 H HB3  . LYS B 1 394 ? -7.259  30.866  73.598 1.00 19.47 ?  360  LYS B HB3  1 
ATOM   11201 H HG2  . LYS B 1 394 ? -7.517  28.615  73.093 1.00 17.17 ?  360  LYS B HG2  1 
ATOM   11202 H HG3  . LYS B 1 394 ? -8.132  29.022  71.685 1.00 17.17 ?  360  LYS B HG3  1 
ATOM   11203 H HD2  . LYS B 1 394 ? -6.082  30.094  71.140 1.00 22.39 ?  360  LYS B HD2  1 
ATOM   11204 H HD3  . LYS B 1 394 ? -5.474  29.575  72.514 1.00 22.39 ?  360  LYS B HD3  1 
ATOM   11205 H HE2  . LYS B 1 394 ? -6.321  27.880  70.437 1.00 21.41 ?  360  LYS B HE2  1 
ATOM   11206 H HE3  . LYS B 1 394 ? -4.800  28.234  70.731 1.00 21.41 ?  360  LYS B HE3  1 
ATOM   11207 H HZ1  . LYS B 1 394 ? -5.041  27.136  72.732 1.00 19.10 ?  360  LYS B HZ1  1 
ATOM   11208 H HZ2  . LYS B 1 394 ? -6.390  26.746  72.378 1.00 19.10 ?  360  LYS B HZ2  1 
ATOM   11209 H HZ3  . LYS B 1 394 ? -5.266  26.231  71.624 1.00 19.10 ?  360  LYS B HZ3  1 
ATOM   11210 N N    . ASN B 1 395 ? -10.080 28.585  74.708 1.00 12.39 ?  361  ASN B N    1 
ATOM   11211 C CA   . ASN B 1 395 ? -10.106 27.508  75.704 1.00 13.66 ?  361  ASN B CA   1 
ATOM   11212 C C    . ASN B 1 395 ? -9.995  26.211  74.913 1.00 12.87 ?  361  ASN B C    1 
ATOM   11213 O O    . ASN B 1 395 ? -10.975 25.642  74.433 1.00 12.94 ?  361  ASN B O    1 
ATOM   11214 C CB   . ASN B 1 395 ? -11.362 27.604  76.528 1.00 16.64 ?  361  ASN B CB   1 
ATOM   11215 C CG   . ASN B 1 395 ? -11.355 28.803  77.459 1.00 22.83 ?  361  ASN B CG   1 
ATOM   11216 O OD1  . ASN B 1 395 ? -12.323 29.573  77.529 1.00 26.52 ?  361  ASN B OD1  1 
ATOM   11217 N ND2  . ASN B 1 395 ? -10.273 28.947  78.213 1.00 27.20 ?  361  ASN B ND2  1 
ATOM   11218 H H    . ASN B 1 395 ? -10.638 28.468  74.065 1.00 14.86 ?  361  ASN B H    1 
ATOM   11219 H HA   . ASN B 1 395 ? -9.353  27.559  76.312 1.00 16.40 ?  361  ASN B HA   1 
ATOM   11220 H HB2  . ASN B 1 395 ? -12.125 27.687  75.935 1.00 19.97 ?  361  ASN B HB2  1 
ATOM   11221 H HB3  . ASN B 1 395 ? -11.449 26.803  77.068 1.00 19.97 ?  361  ASN B HB3  1 
ATOM   11222 H HD21 . ASN B 1 395 ? -9.630  28.378  78.154 1.00 32.64 ?  361  ASN B HD21 1 
ATOM   11223 H HD22 . ASN B 1 395 ? -10.214 29.608  78.759 1.00 32.64 ?  361  ASN B HD22 1 
ATOM   11224 N N    . GLY B 1 396 ? -8.767  25.744  74.756 1.00 14.29 ?  362  GLY B N    1 
ATOM   11225 C CA   . GLY B 1 396 ? -8.534  24.616  73.876 1.00 14.05 ?  362  GLY B CA   1 
ATOM   11226 C C    . GLY B 1 396 ? -8.743  25.046  72.439 1.00 12.56 ?  362  GLY B C    1 
ATOM   11227 O O    . GLY B 1 396 ? -8.170  26.033  71.978 1.00 13.74 ?  362  GLY B O    1 
ATOM   11228 H H    . GLY B 1 396 ? -8.064  26.057  75.141 1.00 17.15 ?  362  GLY B H    1 
ATOM   11229 H HA2  . GLY B 1 396 ? -7.625  24.293  73.983 1.00 16.86 ?  362  GLY B HA2  1 
ATOM   11230 H HA3  . GLY B 1 396 ? -9.151  23.897  74.086 1.00 16.86 ?  362  GLY B HA3  1 
ATOM   11231 N N    . TYR B 1 397 ? -9.597  24.314  71.729 1.00 12.77 ?  363  TYR B N    1 
ATOM   11232 C CA   . TYR B 1 397 ? -9.949  24.639  70.354 1.00 11.10 ?  363  TYR B CA   1 
ATOM   11233 C C    . TYR B 1 397 ? -11.281 25.357  70.269 1.00 10.53 ?  363  TYR B C    1 
ATOM   11234 O O    . TYR B 1 397 ? -11.801 25.542  69.164 1.00 11.37 ?  363  TYR B O    1 
ATOM   11235 C CB   . TYR B 1 397 ? -10.007 23.373  69.498 1.00 11.29 ?  363  TYR B CB   1 
ATOM   11236 C CG   . TYR B 1 397 ? -8.669  22.704  69.262 1.00 15.20 ?  363  TYR B CG   1 
ATOM   11237 C CD1  . TYR B 1 397 ? -7.570  23.418  68.815 1.00 15.64 ?  363  TYR B CD1  1 
ATOM   11238 C CD2  . TYR B 1 397 ? -8.532  21.330  69.448 1.00 23.81 ?  363  TYR B CD2  1 
ATOM   11239 C CE1  . TYR B 1 397 ? -6.347  22.791  68.603 1.00 19.48 ?  363  TYR B CE1  1 
ATOM   11240 C CE2  . TYR B 1 397 ? -7.336  20.694  69.221 1.00 26.69 ?  363  TYR B CE2  1 
ATOM   11241 C CZ   . TYR B 1 397 ? -6.249  21.423  68.801 1.00 27.79 ?  363  TYR B CZ   1 
ATOM   11242 O OH   . TYR B 1 397 ? -5.067  20.740  68.589 1.00 31.59 ?  363  TYR B OH   1 
ATOM   11243 H H    . TYR B 1 397 ? -9.993  23.612  72.030 1.00 15.33 ?  363  TYR B H    1 
ATOM   11244 H HA   . TYR B 1 397 ? -9.257  25.213  69.990 1.00 13.32 ?  363  TYR B HA   1 
ATOM   11245 H HB2  . TYR B 1 397 ? -10.582 22.728  69.939 1.00 13.55 ?  363  TYR B HB2  1 
ATOM   11246 H HB3  . TYR B 1 397 ? -10.374 23.604  68.630 1.00 13.55 ?  363  TYR B HB3  1 
ATOM   11247 H HD1  . TYR B 1 397 ? -7.650  24.331  68.655 1.00 18.76 ?  363  TYR B HD1  1 
ATOM   11248 H HD2  . TYR B 1 397 ? -9.266  20.834  69.730 1.00 28.57 ?  363  TYR B HD2  1 
ATOM   11249 H HE1  . TYR B 1 397 ? -5.605  23.282  68.331 1.00 23.37 ?  363  TYR B HE1  1 
ATOM   11250 H HE2  . TYR B 1 397 ? -7.262  19.776  69.352 1.00 32.03 ?  363  TYR B HE2  1 
ATOM   11251 H HH   . TYR B 1 397 ? -4.445  21.283  68.436 1.00 37.91 ?  363  TYR B HH   1 
ATOM   11252 N N    . ILE B 1 398 ? -11.844 25.759  71.403 1.00 10.60 ?  364  ILE B N    1 
ATOM   11253 C CA   . ILE B 1 398 ? -13.102 26.490  71.464 1.00 10.54 ?  364  ILE B CA   1 
ATOM   11254 C C    . ILE B 1 398 ? -12.787 27.937  71.794 1.00 11.79 ?  364  ILE B C    1 
ATOM   11255 O O    . ILE B 1 398 ? -12.120 28.235  72.793 1.00 13.15 ?  364  ILE B O    1 
ATOM   11256 C CB   . ILE B 1 398 ? -14.070 25.862  72.477 1.00 11.71 ?  364  ILE B CB   1 
ATOM   11257 C CG1  . ILE B 1 398 ? -14.453 24.467  72.013 1.00 14.30 ?  364  ILE B CG1  1 
ATOM   11258 C CG2  . ILE B 1 398 ? -15.307 26.757  72.624 1.00 16.75 ?  364  ILE B CG2  1 
ATOM   11259 C CD1  . ILE B 1 398 ? -15.223 23.653  73.048 1.00 14.85 ?  364  ILE B CD1  1 
ATOM   11260 H H    . ILE B 1 398 ? -11.502 25.615  72.179 1.00 12.73 ?  364  ILE B H    1 
ATOM   11261 H HA   . ILE B 1 398 ? -13.532 26.475  70.594 1.00 12.65 ?  364  ILE B HA   1 
ATOM   11262 H HB   . ILE B 1 398 ? -13.641 25.788  73.344 1.00 14.05 ?  364  ILE B HB   1 
ATOM   11263 H HG12 . ILE B 1 398 ? -15.013 24.545  71.224 1.00 17.16 ?  364  ILE B HG12 1 
ATOM   11264 H HG13 . ILE B 1 398 ? -13.643 23.979  71.797 1.00 17.16 ?  364  ILE B HG13 1 
ATOM   11265 H HG21 . ILE B 1 398 ? -15.956 26.308  73.188 1.00 20.09 ?  364  ILE B HG21 1 
ATOM   11266 H HG22 . ILE B 1 398 ? -15.042 27.597  73.029 1.00 20.09 ?  364  ILE B HG22 1 
ATOM   11267 H HG23 . ILE B 1 398 ? -15.686 26.917  71.746 1.00 20.09 ?  364  ILE B HG23 1 
ATOM   11268 H HD11 . ILE B 1 398 ? -15.458 22.794  72.664 1.00 17.82 ?  364  ILE B HD11 1 
ATOM   11269 H HD12 . ILE B 1 398 ? -14.662 23.525  73.829 1.00 17.82 ?  364  ILE B HD12 1 
ATOM   11270 H HD13 . ILE B 1 398 ? -16.028 24.136  73.295 1.00 17.82 ?  364  ILE B HD13 1 
ATOM   11271 N N    . TYR B 1 399 ? -13.248 28.838  70.948 1.00 10.98 ?  365  TYR B N    1 
ATOM   11272 C CA   . TYR B 1 399 ? -13.055 30.262  71.139 1.00 11.16 ?  365  TYR B CA   1 
ATOM   11273 C C    . TYR B 1 399 ? -14.408 30.927  71.338 1.00 11.95 ?  365  TYR B C    1 
ATOM   11274 O O    . TYR B 1 399 ? -15.408 30.533  70.718 1.00 13.32 ?  365  TYR B O    1 
ATOM   11275 C CB   . TYR B 1 399 ? -12.404 30.932  69.913 1.00 11.29 ?  365  TYR B CB   1 
ATOM   11276 C CG   . TYR B 1 399 ? -11.007 30.475  69.523 1.00 11.84 ?  365  TYR B CG   1 
ATOM   11277 C CD1  . TYR B 1 399 ? -10.806 29.238  68.940 1.00 12.25 ?  365  TYR B CD1  1 
ATOM   11278 C CD2  . TYR B 1 399 ? -9.903  31.306  69.682 1.00 15.19 ?  365  TYR B CD2  1 
ATOM   11279 C CE1  . TYR B 1 399 ? -9.570  28.827  68.535 1.00 17.31 ?  365  TYR B CE1  1 
ATOM   11280 C CE2  . TYR B 1 399 ? -8.642  30.880  69.290 1.00 13.44 ?  365  TYR B CE2  1 
ATOM   11281 C CZ   . TYR B 1 399 ? -8.497  29.642  68.704 1.00 16.01 ?  365  TYR B CZ   1 
ATOM   11282 O OH   . TYR B 1 399 ? -7.260  29.178  68.270 1.00 19.92 ?  365  TYR B OH   1 
ATOM   11283 H H    . TYR B 1 399 ? -13.688 28.644  70.235 1.00 13.18 ?  365  TYR B H    1 
ATOM   11284 H HA   . TYR B 1 399 ? -12.488 30.387  71.916 1.00 13.39 ?  365  TYR B HA   1 
ATOM   11285 H HB2  . TYR B 1 399 ? -12.976 30.770  69.146 1.00 13.55 ?  365  TYR B HB2  1 
ATOM   11286 H HB3  . TYR B 1 399 ? -12.348 31.884  70.089 1.00 13.55 ?  365  TYR B HB3  1 
ATOM   11287 H HD1  . TYR B 1 399 ? -11.533 28.671  68.819 1.00 14.70 ?  365  TYR B HD1  1 
ATOM   11288 H HD2  . TYR B 1 399 ? -10.011 32.152  70.052 1.00 18.23 ?  365  TYR B HD2  1 
ATOM   11289 H HE1  . TYR B 1 399 ? -9.462  27.990  68.144 1.00 20.77 ?  365  TYR B HE1  1 
ATOM   11290 H HE2  . TYR B 1 399 ? -7.901  31.425  69.423 1.00 16.13 ?  365  TYR B HE2  1 
ATOM   11291 H HH   . TYR B 1 399 ? -6.668  29.754  68.423 1.00 23.91 ?  365  TYR B HH   1 
ATOM   11292 N N    . THR B 1 400 ? -14.448 31.958  72.180 1.00 12.08 ?  366  THR B N    1 
ATOM   11293 C CA   . THR B 1 400 ? -15.628 32.796  72.327 1.00 13.61 ?  366  THR B CA   1 
ATOM   11294 C C    . THR B 1 400 ? -15.256 34.260  72.163 1.00 11.39 ?  366  THR B C    1 
ATOM   11295 O O    . THR B 1 400 ? -14.131 34.677  72.459 1.00 13.18 ?  366  THR B O    1 
ATOM   11296 C CB   . THR B 1 400 ? -16.314 32.592  73.702 1.00 14.90 ?  366  THR B CB   1 
ATOM   11297 O OG1  . THR B 1 400 ? -15.411 32.964  74.753 1.00 19.82 ?  366  THR B OG1  1 
ATOM   11298 C CG2  . THR B 1 400 ? -16.766 31.154  73.892 1.00 15.32 ?  366  THR B CG2  1 
ATOM   11299 H H    . THR B 1 400 ? -13.791 32.193  72.684 1.00 14.49 ?  366  THR B H    1 
ATOM   11300 H HA   . THR B 1 400 ? -16.261 32.564  71.631 1.00 16.33 ?  366  THR B HA   1 
ATOM   11301 H HB   . THR B 1 400 ? -17.105 33.152  73.745 1.00 17.88 ?  366  THR B HB   1 
ATOM   11302 H HG1  . THR B 1 400 ? -15.834 33.066  75.472 1.00 23.78 ?  366  THR B HG1  1 
ATOM   11303 H HG21 . THR B 1 400 ? -17.223 31.059  74.742 1.00 18.38 ?  366  THR B HG21 1 
ATOM   11304 H HG22 . THR B 1 400 ? -17.371 30.899  73.178 1.00 18.38 ?  366  THR B HG22 1 
ATOM   11305 H HG23 . THR B 1 400 ? -15.998 30.560  73.880 1.00 18.38 ?  366  THR B HG23 1 
ATOM   11306 N N    . ARG B 1 401 ? -16.216 35.055  71.707 1.00 10.78 ?  367  ARG B N    1 
ATOM   11307 C CA   . ARG B 1 401 ? -16.037 36.497  71.674 1.00 11.26 ?  367  ARG B CA   1 
ATOM   11308 C C    . ARG B 1 401 ? -17.393 37.188  71.715 1.00 12.08 ?  367  ARG B C    1 
ATOM   11309 O O    . ARG B 1 401 ? -18.352 36.731  71.084 1.00 14.45 ?  367  ARG B O    1 
ATOM   11310 C CB   . ARG B 1 401 ? -15.254 36.938  70.427 1.00 12.06 ?  367  ARG B CB   1 
ATOM   11311 C CG   . ARG B 1 401 ? -14.709 38.328  70.543 1.00 12.55 ?  367  ARG B CG   1 
ATOM   11312 C CD   . ARG B 1 401 ? -13.835 38.701  69.364 1.00 10.89 ?  367  ARG B CD   1 
ATOM   11313 N NE   . ARG B 1 401 ? -13.192 39.985  69.575 1.00 11.83 ?  367  ARG B NE   1 
ATOM   11314 C CZ   . ARG B 1 401 ? -12.440 40.600  68.675 1.00 11.86 ?  367  ARG B CZ   1 
ATOM   11315 N NH1  . ARG B 1 401 ? -12.267 40.098  67.470 1.00 11.55 ?  367  ARG B NH1  1 
ATOM   11316 N NH2  . ARG B 1 401 ? -11.843 41.742  68.996 1.00 13.53 ?  367  ARG B NH2  1 
ATOM   11317 H H    . ARG B 1 401 ? -16.976 34.783  71.411 1.00 12.94 ?  367  ARG B H    1 
ATOM   11318 H HA   . ARG B 1 401 ? -15.543 36.767  72.464 1.00 13.51 ?  367  ARG B HA   1 
ATOM   11319 H HB2  . ARG B 1 401 ? -14.507 36.333  70.293 1.00 14.47 ?  367  ARG B HB2  1 
ATOM   11320 H HB3  . ARG B 1 401 ? -15.845 36.910  69.658 1.00 14.47 ?  367  ARG B HB3  1 
ATOM   11321 H HG2  . ARG B 1 401 ? -15.447 38.957  70.582 1.00 15.05 ?  367  ARG B HG2  1 
ATOM   11322 H HG3  . ARG B 1 401 ? -14.174 38.394  71.349 1.00 15.05 ?  367  ARG B HG3  1 
ATOM   11323 H HD2  . ARG B 1 401 ? -13.146 38.028  69.248 1.00 13.06 ?  367  ARG B HD2  1 
ATOM   11324 H HD3  . ARG B 1 401 ? -14.380 38.759  68.564 1.00 13.06 ?  367  ARG B HD3  1 
ATOM   11325 H HE   . ARG B 1 401 ? -13.306 40.372  70.335 1.00 14.19 ?  367  ARG B HE   1 
ATOM   11326 H HH11 . ARG B 1 401 ? -12.645 39.356  67.255 1.00 13.87 ?  367  ARG B HH11 1 
ATOM   11327 H HH12 . ARG B 1 401 ? -11.775 40.512  66.899 1.00 13.87 ?  367  ARG B HH12 1 
ATOM   11328 H HH21 . ARG B 1 401 ? -11.947 42.075  69.783 1.00 16.24 ?  367  ARG B HH21 1 
ATOM   11329 H HH22 . ARG B 1 401 ? -11.353 42.148  68.418 1.00 16.24 ?  367  ARG B HH22 1 
ATOM   11330 N N    . LYS B 1 402 ? -17.457 38.318  72.403 1.00 13.26 ?  368  LYS B N    1 
ATOM   11331 C CA   . LYS B 1 402 ? -18.692 39.077  72.540 1.00 14.80 ?  368  LYS B CA   1 
ATOM   11332 C C    . LYS B 1 402 ? -18.567 40.394  71.781 1.00 14.24 ?  368  LYS B C    1 
ATOM   11333 O O    . LYS B 1 402 ? -17.547 41.090  71.880 1.00 14.13 ?  368  LYS B O    1 
ATOM   11334 C CB   . LYS B 1 402 ? -19.025 39.283  74.028 1.00 21.36 ?  368  LYS B CB   1 
ATOM   11335 C CG   . LYS B 1 402 ? -19.923 40.456  74.394 1.00 25.89 ?  368  LYS B CG   1 
ATOM   11336 C CD   . LYS B 1 402 ? -19.977 40.637  75.932 1.00 31.04 ?  368  LYS B CD   1 
ATOM   11337 C CE   . LYS B 1 402 ? -21.285 41.271  76.430 1.00 37.18 ?  368  LYS B CE   1 
ATOM   11338 N NZ   . LYS B 1 402 ? -22.522 40.480  76.150 1.00 35.87 ?  368  LYS B NZ   1 
ATOM   11339 H H    . LYS B 1 402 ? -16.785 38.673  72.807 1.00 15.92 ?  368  LYS B H    1 
ATOM   11340 H HA   . LYS B 1 402 ? -19.436 38.600  72.141 1.00 17.76 ?  368  LYS B HA   1 
ATOM   11341 H HB2  . LYS B 1 402 ? -19.468 38.482  74.346 1.00 25.63 ?  368  LYS B HB2  1 
ATOM   11342 H HB3  . LYS B 1 402 ? -18.190 39.412  74.504 1.00 25.63 ?  368  LYS B HB3  1 
ATOM   11343 H HG2  . LYS B 1 402 ? -19.573 41.269  73.999 1.00 31.07 ?  368  LYS B HG2  1 
ATOM   11344 H HG3  . LYS B 1 402 ? -20.823 40.290  74.070 1.00 31.07 ?  368  LYS B HG3  1 
ATOM   11345 H HD2  . LYS B 1 402 ? -19.891 39.768  76.354 1.00 37.25 ?  368  LYS B HD2  1 
ATOM   11346 H HD3  . LYS B 1 402 ? -19.246 41.213  76.206 1.00 37.25 ?  368  LYS B HD3  1 
ATOM   11347 H HE2  . LYS B 1 402 ? -21.225 41.383  77.392 1.00 44.62 ?  368  LYS B HE2  1 
ATOM   11348 H HE3  . LYS B 1 402 ? -21.390 42.135  76.001 1.00 44.62 ?  368  LYS B HE3  1 
ATOM   11349 H HZ1  . LYS B 1 402 ? -23.236 40.915  76.455 1.00 43.04 ?  368  LYS B HZ1  1 
ATOM   11350 H HZ2  . LYS B 1 402 ? -22.612 40.356  75.274 1.00 43.04 ?  368  LYS B HZ2  1 
ATOM   11351 H HZ3  . LYS B 1 402 ? -22.473 39.687  76.551 1.00 43.04 ?  368  LYS B HZ3  1 
ATOM   11352 N N    . PHE B 1 403 ? -19.599 40.711  71.010 1.00 13.63 ?  369  PHE B N    1 
ATOM   11353 C CA   . PHE B 1 403 ? -19.800 41.991  70.354 1.00 12.59 ?  369  PHE B CA   1 
ATOM   11354 C C    . PHE B 1 403 ? -21.079 42.612  70.913 1.00 13.84 ?  369  PHE B C    1 
ATOM   11355 O O    . PHE B 1 403 ? -21.869 41.933  71.577 1.00 15.43 ?  369  PHE B O    1 
ATOM   11356 C CB   . PHE B 1 403 ? -19.933 41.804  68.829 1.00 12.40 ?  369  PHE B CB   1 
ATOM   11357 C CG   . PHE B 1 403 ? -18.700 41.220  68.174 1.00 11.56 ?  369  PHE B CG   1 
ATOM   11358 C CD1  . PHE B 1 403 ? -18.409 39.875  68.262 1.00 11.52 ?  369  PHE B CD1  1 
ATOM   11359 C CD2  . PHE B 1 403 ? -17.818 42.040  67.491 1.00 11.22 ?  369  PHE B CD2  1 
ATOM   11360 C CE1  . PHE B 1 403 ? -17.266 39.367  67.695 1.00 11.41 ?  369  PHE B CE1  1 
ATOM   11361 C CE2  . PHE B 1 403 ? -16.682 41.516  66.903 1.00 11.88 ?  369  PHE B CE2  1 
ATOM   11362 C CZ   . PHE B 1 403 ? -16.405 40.192  67.013 1.00 11.01 ?  369  PHE B CZ   1 
ATOM   11363 H H    . PHE B 1 403 ? -20.239 40.162  70.842 1.00 16.35 ?  369  PHE B H    1 
ATOM   11364 H HA   . PHE B 1 403 ? -19.050 42.582  70.522 1.00 15.11 ?  369  PHE B HA   1 
ATOM   11365 H HB2  . PHE B 1 403 ? -20.674 41.203  68.652 1.00 14.88 ?  369  PHE B HB2  1 
ATOM   11366 H HB3  . PHE B 1 403 ? -20.102 42.668  68.422 1.00 14.88 ?  369  PHE B HB3  1 
ATOM   11367 H HD1  . PHE B 1 403 ? -18.992 39.307  68.711 1.00 13.82 ?  369  PHE B HD1  1 
ATOM   11368 H HD2  . PHE B 1 403 ? -17.991 42.951  67.428 1.00 13.47 ?  369  PHE B HD2  1 
ATOM   11369 H HE1  . PHE B 1 403 ? -17.075 38.460  67.773 1.00 13.69 ?  369  PHE B HE1  1 
ATOM   11370 H HE2  . PHE B 1 403 ? -16.107 42.073  66.430 1.00 14.25 ?  369  PHE B HE2  1 
ATOM   11371 H HZ   . PHE B 1 403 ? -15.633 39.844  66.628 1.00 13.22 ?  369  PHE B HZ   1 
ATOM   11372 N N    . GLU B 1 404 ? -21.300 43.892  70.610 1.00 15.29 ?  370  GLU B N    1 
ATOM   11373 C CA   . GLU B 1 404 ? -22.459 44.588  71.170 1.00 14.87 ?  370  GLU B CA   1 
ATOM   11374 C C    . GLU B 1 404 ? -23.760 43.853  70.877 1.00 19.02 ?  370  GLU B C    1 
ATOM   11375 O O    . GLU B 1 404 ? -24.641 43.765  71.743 1.00 18.37 ?  370  GLU B O    1 
ATOM   11376 C CB   . GLU B 1 404 ? -22.513 46.043  70.684 1.00 16.33 ?  370  GLU B CB   1 
ATOM   11377 C CG   . GLU B 1 404 ? -21.421 46.910  71.309 1.00 25.43 ?  370  GLU B CG   1 
ATOM   11378 C CD   . GLU B 1 404 ? -21.161 48.251  70.613 1.00 36.74 ?  370  GLU B CD   1 
ATOM   11379 O OE1  . GLU B 1 404 ? -21.473 48.431  69.412 1.00 30.12 ?  370  GLU B OE1  1 
ATOM   11380 O OE2  . GLU B 1 404 ? -20.625 49.149  71.302 1.00 42.86 ?  370  GLU B OE2  1 
ATOM   11381 H H    . GLU B 1 404 ? -20.805 44.370  70.095 1.00 18.35 ?  370  GLU B H    1 
ATOM   11382 H HA   . GLU B 1 404 ? -22.355 44.617  72.134 1.00 17.84 ?  370  GLU B HA   1 
ATOM   11383 H HB2  . GLU B 1 404 ? -22.398 46.060  69.721 1.00 19.60 ?  370  GLU B HB2  1 
ATOM   11384 H HB3  . GLU B 1 404 ? -23.373 46.424  70.922 1.00 19.60 ?  370  GLU B HB3  1 
ATOM   11385 H HG2  . GLU B 1 404 ? -21.673 47.106  72.225 1.00 30.52 ?  370  GLU B HG2  1 
ATOM   11386 H HG3  . GLU B 1 404 ? -20.589 46.412  71.293 1.00 30.52 ?  370  GLU B HG3  1 
ATOM   11387 N N    . ASN B 1 405 ? -23.887 43.285  69.676 1.00 14.38 ?  371  ASN B N    1 
ATOM   11388 C CA   . ASN B 1 405 ? -25.127 42.654  69.242 1.00 14.96 ?  371  ASN B CA   1 
ATOM   11389 C C    . ASN B 1 405 ? -24.955 41.192  68.849 1.00 13.15 ?  371  ASN B C    1 
ATOM   11390 O O    . ASN B 1 405 ? -25.806 40.652  68.146 1.00 14.55 ?  371  ASN B O    1 
ATOM   11391 C CB   . ASN B 1 405 ? -25.736 43.439  68.076 1.00 16.75 ?  371  ASN B CB   1 
ATOM   11392 C CG   . ASN B 1 405 ? -26.004 44.883  68.427 1.00 21.15 ?  371  ASN B CG   1 
ATOM   11393 O OD1  . ASN B 1 405 ? -25.315 45.789  67.966 1.00 26.39 ?  371  ASN B OD1  1 
ATOM   11394 N ND2  . ASN B 1 405 ? -27.017 45.104  69.239 1.00 28.48 ?  371  ASN B ND2  1 
ATOM   11395 H H    . ASN B 1 405 ? -23.259 43.253  69.090 1.00 17.26 ?  371  ASN B H    1 
ATOM   11396 H HA   . ASN B 1 405 ? -25.744 42.673  69.990 1.00 17.95 ?  371  ASN B HA   1 
ATOM   11397 H HB2  . ASN B 1 405 ? -25.122 43.421  67.326 1.00 20.10 ?  371  ASN B HB2  1 
ATOM   11398 H HB3  . ASN B 1 405 ? -26.579 43.030  67.825 1.00 20.10 ?  371  ASN B HB3  1 
ATOM   11399 H HD21 . ASN B 1 405 ? -27.482 44.444  69.537 1.00 34.17 ?  371  ASN B HD21 1 
ATOM   11400 H HD22 . ASN B 1 405 ? -27.214 45.908  69.472 1.00 34.17 ?  371  ASN B HD22 1 
ATOM   11401 N N    . LEU B 1 406 ? -23.889 40.534  69.299 1.00 14.23 ?  372  LEU B N    1 
ATOM   11402 C CA   . LEU B 1 406 ? -23.630 39.164  68.881 1.00 12.60 ?  372  LEU B CA   1 
ATOM   11403 C C    . LEU B 1 406 ? -22.699 38.478  69.857 1.00 14.27 ?  372  LEU B C    1 
ATOM   11404 O O    . LEU B 1 406 ? -21.711 39.066  70.295 1.00 15.53 ?  372  LEU B O    1 
ATOM   11405 C CB   . LEU B 1 406 ? -22.966 39.144  67.490 1.00 14.82 ?  372  LEU B CB   1 
ATOM   11406 C CG   . LEU B 1 406 ? -22.418 37.815  66.988 1.00 11.39 ?  372  LEU B CG   1 
ATOM   11407 C CD1  . LEU B 1 406 ? -23.532 36.797  66.728 1.00 12.88 ?  372  LEU B CD1  1 
ATOM   11408 C CD2  . LEU B 1 406 ? -21.595 38.016  65.721 1.00 13.03 ?  372  LEU B CD2  1 
ATOM   11409 H H    . LEU B 1 406 ? -23.306 40.859  69.841 1.00 17.08 ?  372  LEU B H    1 
ATOM   11410 H HA   . LEU B 1 406 ? -24.473 38.683  68.873 1.00 15.11 ?  372  LEU B HA   1 
ATOM   11411 H HB2  . LEU B 1 406 ? -23.626 39.437  66.842 1.00 17.78 ?  372  LEU B HB2  1 
ATOM   11412 H HB3  . LEU B 1 406 ? -22.221 39.765  67.508 1.00 17.78 ?  372  LEU B HB3  1 
ATOM   11413 H HG   . LEU B 1 406 ? -21.845 37.452  67.682 1.00 13.66 ?  372  LEU B HG   1 
ATOM   11414 H HD11 . LEU B 1 406 ? -23.134 35.952  66.468 1.00 15.46 ?  372  LEU B HD11 1 
ATOM   11415 H HD12 . LEU B 1 406 ? -24.051 36.683  67.539 1.00 15.46 ?  372  LEU B HD12 1 
ATOM   11416 H HD13 . LEU B 1 406 ? -24.102 37.128  66.015 1.00 15.46 ?  372  LEU B HD13 1 
ATOM   11417 H HD21 . LEU B 1 406 ? -21.275 37.154  65.412 1.00 15.63 ?  372  LEU B HD21 1 
ATOM   11418 H HD22 . LEU B 1 406 ? -22.155 38.423  65.042 1.00 15.63 ?  372  LEU B HD22 1 
ATOM   11419 H HD23 . LEU B 1 406 ? -20.843 38.595  65.921 1.00 15.63 ?  372  LEU B HD23 1 
ATOM   11420 N N    . ASP B 1 407 ? -22.985 37.217  70.149 1.00 12.36 ?  373  ASP B N    1 
ATOM   11421 C CA   . ASP B 1 407 ? -22.052 36.352  70.851 1.00 14.92 ?  373  ASP B CA   1 
ATOM   11422 C C    . ASP B 1 407 ? -21.614 35.225  69.934 1.00 12.93 ?  373  ASP B C    1 
ATOM   11423 O O    . ASP B 1 407 ? -22.445 34.577  69.281 1.00 13.74 ?  373  ASP B O    1 
ATOM   11424 C CB   . ASP B 1 407 ? -22.600 35.842  72.192 1.00 18.89 ?  373  ASP B CB   1 
ATOM   11425 C CG   . ASP B 1 407 ? -22.749 36.970  73.212 1.00 18.80 ?  373  ASP B CG   1 
ATOM   11426 O OD1  . ASP B 1 407 ? -21.746 37.275  73.886 1.00 32.26 ?  373  ASP B OD1  1 
ATOM   11427 O OD2  . ASP B 1 407 ? -23.823 37.586  73.292 1.00 30.24 ?  373  ASP B OD2  1 
ATOM   11428 H H    . ASP B 1 407 ? -23.728 36.834  69.947 1.00 14.83 ?  373  ASP B H    1 
ATOM   11429 H HA   . ASP B 1 407 ? -21.259 36.863  71.077 1.00 17.90 ?  373  ASP B HA   1 
ATOM   11430 H HB2  . ASP B 1 407 ? -23.473 35.444  72.049 1.00 22.67 ?  373  ASP B HB2  1 
ATOM   11431 H HB3  . ASP B 1 407 ? -21.990 35.182  72.556 1.00 22.67 ?  373  ASP B HB3  1 
ATOM   11432 N N    . VAL B 1 408 ? -20.305 34.995  69.884 1.00 11.46 ?  374  VAL B N    1 
ATOM   11433 C CA   . VAL B 1 408 ? -19.707 33.990  69.016 1.00 11.81 ?  374  VAL B CA   1 
ATOM   11434 C C    . VAL B 1 408 ? -19.171 32.843  69.848 1.00 10.54 ?  374  VAL B C    1 
ATOM   11435 O O    . VAL B 1 408 ? -18.444 33.063  70.831 1.00 11.82 ?  374  VAL B O    1 
ATOM   11436 C CB   . VAL B 1 408 ? -18.553 34.592  68.193 1.00 11.86 ?  374  VAL B CB   1 
ATOM   11437 C CG1  . VAL B 1 408 ? -17.922 33.529  67.299 1.00 12.81 ?  374  VAL B CG1  1 
ATOM   11438 C CG2  . VAL B 1 408 ? -19.037 35.781  67.402 1.00 12.67 ?  374  VAL B CG2  1 
ATOM   11439 H H    . VAL B 1 408 ? -19.728 35.422  70.358 1.00 13.76 ?  374  VAL B H    1 
ATOM   11440 H HA   . VAL B 1 408 ? -20.401 33.648  68.431 1.00 14.17 ?  374  VAL B HA   1 
ATOM   11441 H HB   . VAL B 1 408 ? -17.859 34.909  68.792 1.00 14.23 ?  374  VAL B HB   1 
ATOM   11442 H HG11 . VAL B 1 408 ? -17.291 33.955  66.697 1.00 15.38 ?  374  VAL B HG11 1 
ATOM   11443 H HG12 . VAL B 1 408 ? -17.462 32.880  67.855 1.00 15.38 ?  374  VAL B HG12 1 
ATOM   11444 H HG13 . VAL B 1 408 ? -18.621 33.090  66.788 1.00 15.38 ?  374  VAL B HG13 1 
ATOM   11445 H HG21 . VAL B 1 408 ? -18.339 36.058  66.788 1.00 15.20 ?  374  VAL B HG21 1 
ATOM   11446 H HG22 . VAL B 1 408 ? -19.832 35.528  66.907 1.00 15.20 ?  374  VAL B HG22 1 
ATOM   11447 H HG23 . VAL B 1 408 ? -19.246 36.504  68.014 1.00 15.20 ?  374  VAL B HG23 1 
ATOM   11448 N N    A TRP B 1 409 ? -19.471 31.626  69.415 0.61 11.20 ?  375  TRP B N    1 
ATOM   11449 N N    B TRP B 1 409 ? -19.523 31.619  69.461 0.39 11.20 ?  375  TRP B N    1 
ATOM   11450 C CA   A TRP B 1 409 ? -18.913 30.412  69.976 0.61 13.19 ?  375  TRP B CA   1 
ATOM   11451 C CA   B TRP B 1 409 ? -18.919 30.402  69.979 0.39 13.21 ?  375  TRP B CA   1 
ATOM   11452 C C    A TRP B 1 409 ? -18.409 29.566  68.816 0.61 14.31 ?  375  TRP B C    1 
ATOM   11453 C C    B TRP B 1 409 ? -18.381 29.648  68.772 0.39 14.31 ?  375  TRP B C    1 
ATOM   11454 O O    A TRP B 1 409 ? -19.176 29.258  67.896 0.61 14.13 ?  375  TRP B O    1 
ATOM   11455 O O    B TRP B 1 409 ? -19.094 29.501  67.773 0.39 12.94 ?  375  TRP B O    1 
ATOM   11456 C CB   A TRP B 1 409 ? -19.993 29.679  70.774 0.61 14.54 ?  375  TRP B CB   1 
ATOM   11457 C CB   B TRP B 1 409 ? -19.967 29.529  70.673 0.39 14.63 ?  375  TRP B CB   1 
ATOM   11458 C CG   A TRP B 1 409 ? -19.501 28.420  71.248 0.61 14.34 ?  375  TRP B CG   1 
ATOM   11459 C CG   B TRP B 1 409 ? -20.260 29.903  72.090 0.39 16.93 ?  375  TRP B CG   1 
ATOM   11460 C CD1  A TRP B 1 409 ? -18.851 28.196  72.413 0.61 11.74 ?  375  TRP B CD1  1 
ATOM   11461 C CD1  B TRP B 1 409 ? -21.146 30.839  72.513 0.39 19.32 ?  375  TRP B CD1  1 
ATOM   11462 C CD2  A TRP B 1 409 ? -19.564 27.166  70.567 0.61 11.54 ?  375  TRP B CD2  1 
ATOM   11463 C CD2  B TRP B 1 409 ? -19.675 29.344  73.272 0.39 13.12 ?  375  TRP B CD2  1 
ATOM   11464 N NE1  A TRP B 1 409 ? -18.511 26.869  72.520 0.61 12.29 ?  375  TRP B NE1  1 
ATOM   11465 N NE1  B TRP B 1 409 ? -21.154 30.904  73.886 0.39 19.08 ?  375  TRP B NE1  1 
ATOM   11466 C CE2  A TRP B 1 409 ? -18.925 26.216  71.389 0.61 12.68 ?  375  TRP B CE2  1 
ATOM   11467 C CE2  B TRP B 1 409 ? -20.256 29.995  74.376 0.39 21.11 ?  375  TRP B CE2  1 
ATOM   11468 C CE3  A TRP B 1 409 ? -20.097 26.751  69.337 0.61 12.84 ?  375  TRP B CE3  1 
ATOM   11469 C CE3  B TRP B 1 409 ? -18.719 28.357  73.502 0.39 18.15 ?  375  TRP B CE3  1 
ATOM   11470 C CZ2  A TRP B 1 409 ? -18.809 24.877  71.023 0.61 14.51 ?  375  TRP B CZ2  1 
ATOM   11471 C CZ2  B TRP B 1 409 ? -19.909 29.686  75.693 0.39 15.93 ?  375  TRP B CZ2  1 
ATOM   11472 C CZ3  A TRP B 1 409 ? -19.987 25.431  68.985 0.61 11.35 ?  375  TRP B CZ3  1 
ATOM   11473 C CZ3  B TRP B 1 409 ? -18.373 28.059  74.795 0.39 19.79 ?  375  TRP B CZ3  1 
ATOM   11474 C CH2  A TRP B 1 409 ? -19.352 24.502  69.830 0.61 9.12  ?  375  TRP B CH2  1 
ATOM   11475 C CH2  B TRP B 1 409 ? -18.971 28.709  75.875 0.39 16.73 ?  375  TRP B CH2  1 
ATOM   11476 H H    A TRP B 1 409 ? -20.018 31.475  68.769 0.61 13.44 ?  375  TRP B H    1 
ATOM   11477 H H    B TRP B 1 409 ? -20.134 31.466  68.875 0.39 13.44 ?  375  TRP B H    1 
ATOM   11478 H HA   A TRP B 1 409 ? -18.165 30.598  70.565 0.61 15.83 ?  375  TRP B HA   1 
ATOM   11479 H HA   B TRP B 1 409 ? -18.215 30.605  70.614 0.39 15.85 ?  375  TRP B HA   1 
ATOM   11480 H HB2  A TRP B 1 409 ? -20.253 30.217  71.538 0.61 17.45 ?  375  TRP B HB2  1 
ATOM   11481 H HB2  B TRP B 1 409 ? -20.798 29.593  70.177 0.39 17.55 ?  375  TRP B HB2  1 
ATOM   11482 H HB3  A TRP B 1 409 ? -20.761 29.516  70.205 0.61 17.45 ?  375  TRP B HB3  1 
ATOM   11483 H HB3  B TRP B 1 409 ? -19.651 28.612  70.674 0.39 17.55 ?  375  TRP B HB3  1 
ATOM   11484 H HD1  A TRP B 1 409 ? -18.662 28.847  73.050 0.61 14.09 ?  375  TRP B HD1  1 
ATOM   11485 H HD1  B TRP B 1 409 ? -21.673 31.363  71.954 0.39 23.18 ?  375  TRP B HD1  1 
ATOM   11486 H HE1  A TRP B 1 409 ? -18.106 26.507  73.187 0.61 14.75 ?  375  TRP B HE1  1 
ATOM   11487 H HE1  B TRP B 1 409 ? -21.643 31.429  74.360 0.39 22.90 ?  375  TRP B HE1  1 
ATOM   11488 H HE3  A TRP B 1 409 ? -20.517 27.359  68.772 0.61 15.40 ?  375  TRP B HE3  1 
ATOM   11489 H HE3  B TRP B 1 409 ? -18.322 27.907  72.791 0.39 21.79 ?  375  TRP B HE3  1 
ATOM   11490 H HZ2  A TRP B 1 409 ? -18.377 24.263  71.571 0.61 17.41 ?  375  TRP B HZ2  1 
ATOM   11491 H HZ2  B TRP B 1 409 ? -20.299 30.125  76.414 0.39 19.11 ?  375  TRP B HZ2  1 
ATOM   11492 H HZ3  A TRP B 1 409 ? -20.337 25.144  68.172 0.61 13.62 ?  375  TRP B HZ3  1 
ATOM   11493 H HZ3  B TRP B 1 409 ? -17.726 27.411  74.956 0.39 23.75 ?  375  TRP B HZ3  1 
ATOM   11494 H HH2  A TRP B 1 409 ? -19.303 23.610  69.569 0.61 10.95 ?  375  TRP B HH2  1 
ATOM   11495 H HH2  B TRP B 1 409 ? -18.726 28.471  76.740 0.39 20.08 ?  375  TRP B HH2  1 
ATOM   11496 N N    . LEU B 1 410 ? -17.123 29.215  68.843 1.00 12.82 ?  376  LEU B N    1 
ATOM   11497 C CA   . LEU B 1 410 ? -16.454 28.532  67.739 1.00 13.20 ?  376  LEU B CA   1 
ATOM   11498 C C    . LEU B 1 410 ? -15.740 27.290  68.249 1.00 14.51 ?  376  LEU B C    1 
ATOM   11499 O O    . LEU B 1 410 ? -14.969 27.389  69.201 1.00 15.03 ?  376  LEU B O    1 
ATOM   11500 C CB   . LEU B 1 410 ? -15.375 29.473  67.146 1.00 13.24 ?  376  LEU B CB   1 
ATOM   11501 C CG   . LEU B 1 410 ? -14.375 28.955  66.122 1.00 14.34 ?  376  LEU B CG   1 
ATOM   11502 C CD1  . LEU B 1 410 ? -15.096 28.468  64.875 1.00 15.04 ?  376  LEU B CD1  1 
ATOM   11503 C CD2  . LEU B 1 410 ? -13.341 30.028  65.760 1.00 15.66 ?  376  LEU B CD2  1 
ATOM   11504 H H    . LEU B 1 410 ? -16.600 29.366  69.509 1.00 15.39 ?  376  LEU B H    1 
ATOM   11505 H HA   . LEU B 1 410 ? -17.112 28.268  67.077 1.00 15.84 ?  376  LEU B HA   1 
ATOM   11506 H HB2  . LEU B 1 410 ? -15.842 30.206  66.717 1.00 15.89 ?  376  LEU B HB2  1 
ATOM   11507 H HB3  . LEU B 1 410 ? -14.848 29.805  67.890 1.00 15.89 ?  376  LEU B HB3  1 
ATOM   11508 H HG   . LEU B 1 410 ? -13.896 28.208  66.512 1.00 17.20 ?  376  LEU B HG   1 
ATOM   11509 H HD11 . LEU B 1 410 ? -14.450 28.064  64.274 1.00 18.05 ?  376  LEU B HD11 1 
ATOM   11510 H HD12 . LEU B 1 410 ? -15.764 27.813  65.131 1.00 18.05 ?  376  LEU B HD12 1 
ATOM   11511 H HD13 . LEU B 1 410 ? -15.523 29.223  64.441 1.00 18.05 ?  376  LEU B HD13 1 
ATOM   11512 H HD21 . LEU B 1 410 ? -12.730 29.667  65.099 1.00 18.79 ?  376  LEU B HD21 1 
ATOM   11513 H HD22 . LEU B 1 410 ? -13.802 30.801  65.396 1.00 18.79 ?  376  LEU B HD22 1 
ATOM   11514 H HD23 . LEU B 1 410 ? -12.853 30.280  66.559 1.00 18.79 ?  376  LEU B HD23 1 
ATOM   11515 N N    . ASN B 1 411 ? -15.952 26.140  67.611 1.00 10.98 ?  377  ASN B N    1 
ATOM   11516 C CA   . ASN B 1 411 ? -15.183 24.933  67.921 1.00 11.30 ?  377  ASN B CA   1 
ATOM   11517 C C    . ASN B 1 411 ? -14.435 24.472  66.677 1.00 10.16 ?  377  ASN B C    1 
ATOM   11518 O O    . ASN B 1 411 ? -15.035 23.893  65.774 1.00 11.24 ?  377  ASN B O    1 
ATOM   11519 C CB   . ASN B 1 411 ? -16.088 23.806  68.429 1.00 11.57 ?  377  ASN B CB   1 
ATOM   11520 C CG   . ASN B 1 411 ? -15.307 22.635  68.978 1.00 12.78 ?  377  ASN B CG   1 
ATOM   11521 O OD1  . ASN B 1 411 ? -14.097 22.523  68.780 1.00 14.54 ?  377  ASN B OD1  1 
ATOM   11522 N ND2  . ASN B 1 411 ? -16.008 21.731  69.676 1.00 14.92 ?  377  ASN B ND2  1 
ATOM   11523 H H    . ASN B 1 411 ? -16.539 26.033  66.992 1.00 13.18 ?  377  ASN B H    1 
ATOM   11524 H HA   . ASN B 1 411 ? -14.535 25.161  68.606 1.00 13.56 ?  377  ASN B HA   1 
ATOM   11525 H HB2  . ASN B 1 411 ? -16.652 24.150  69.139 1.00 13.89 ?  377  ASN B HB2  1 
ATOM   11526 H HB3  . ASN B 1 411 ? -16.636 23.485  67.696 1.00 13.89 ?  377  ASN B HB3  1 
ATOM   11527 H HD21 . ASN B 1 411 ? -15.612 21.045  70.011 1.00 17.91 ?  377  ASN B HD21 1 
ATOM   11528 H HD22 . ASN B 1 411 ? -16.854 21.837  69.790 1.00 17.91 ?  377  ASN B HD22 1 
ATOM   11529 N N    . LEU B 1 412 ? -13.117 24.672  66.650 1.00 10.09 ?  378  LEU B N    1 
ATOM   11530 C CA   . LEU B 1 412 ? -12.344 24.275  65.484 1.00 11.61 ?  378  LEU B CA   1 
ATOM   11531 C C    . LEU B 1 412 ? -12.354 22.770  65.308 1.00 13.08 ?  378  LEU B C    1 
ATOM   11532 O O    . LEU B 1 412 ? -12.268 22.277  64.177 1.00 15.51 ?  378  LEU B O    1 
ATOM   11533 C CB   . LEU B 1 412 ? -10.899 24.750  65.596 1.00 12.53 ?  378  LEU B CB   1 
ATOM   11534 C CG   . LEU B 1 412 ? -10.678 26.243  65.693 1.00 11.28 ?  378  LEU B CG   1 
ATOM   11535 C CD1  . LEU B 1 412 ? -9.178  26.513  65.863 1.00 14.37 ?  378  LEU B CD1  1 
ATOM   11536 C CD2  . LEU B 1 412 ? -11.197 26.936  64.451 1.00 14.54 ?  378  LEU B CD2  1 
ATOM   11537 H H    . LEU B 1 412 ? -12.658 25.030  67.283 1.00 12.11 ?  378  LEU B H    1 
ATOM   11538 H HA   . LEU B 1 412 ? -12.742 24.696  64.706 1.00 13.93 ?  378  LEU B HA   1 
ATOM   11539 H HB2  . LEU B 1 412 ? -10.515 24.354  66.394 1.00 15.04 ?  378  LEU B HB2  1 
ATOM   11540 H HB3  . LEU B 1 412 ? -10.421 24.442  64.810 1.00 15.04 ?  378  LEU B HB3  1 
ATOM   11541 H HG   . LEU B 1 412 ? -11.158 26.601  66.456 1.00 13.53 ?  378  LEU B HG   1 
ATOM   11542 H HD11 . LEU B 1 412 ? -9.016  27.464  65.766 1.00 17.24 ?  378  LEU B HD11 1 
ATOM   11543 H HD12 . LEU B 1 412 ? -8.902  26.218  66.745 1.00 17.24 ?  378  LEU B HD12 1 
ATOM   11544 H HD13 . LEU B 1 412 ? -8.690  26.023  65.183 1.00 17.24 ?  378  LEU B HD13 1 
ATOM   11545 H HD21 . LEU B 1 412 ? -10.878 27.851  64.443 1.00 17.44 ?  378  LEU B HD21 1 
ATOM   11546 H HD22 . LEU B 1 412 ? -10.873 26.465  63.668 1.00 17.44 ?  378  LEU B HD22 1 
ATOM   11547 H HD23 . LEU B 1 412 ? -12.167 26.924  64.466 1.00 17.44 ?  378  LEU B HD23 1 
ATOM   11548 N N    . GLU B 1 413 ? -12.450 22.015  66.407 1.00 12.71 ?  379  GLU B N    1 
ATOM   11549 C CA   . GLU B 1 413 ? -12.316 20.569  66.318 1.00 15.39 ?  379  GLU B CA   1 
ATOM   11550 C C    . GLU B 1 413 ? -13.479 19.946  65.558 1.00 15.37 ?  379  GLU B C    1 
ATOM   11551 O O    . GLU B 1 413 ? -13.286 18.998  64.784 1.00 20.16 ?  379  GLU B O    1 
ATOM   11552 C CB   . GLU B 1 413 ? -12.198 19.996  67.729 1.00 16.96 ?  379  GLU B CB   1 
ATOM   11553 C CG   . GLU B 1 413 ? -11.946 18.515  67.800 1.00 28.40 ?  379  GLU B CG   1 
ATOM   11554 C CD   . GLU B 1 413 ? -11.315 18.126  69.114 1.00 33.37 ?  379  GLU B CD   1 
ATOM   11555 O OE1  . GLU B 1 413 ? -11.732 18.674  70.156 1.00 36.06 ?  379  GLU B OE1  1 
ATOM   11556 O OE2  . GLU B 1 413 ? -10.389 17.289  69.100 1.00 40.35 ?  379  GLU B OE2  1 
ATOM   11557 H H    . GLU B 1 413 ? -12.590 22.315  67.201 1.00 15.25 ?  379  GLU B H    1 
ATOM   11558 H HA   . GLU B 1 413 ? -11.509 20.345  65.829 1.00 18.47 ?  379  GLU B HA   1 
ATOM   11559 H HB2  . GLU B 1 413 ? -11.461 20.438  68.178 1.00 20.35 ?  379  GLU B HB2  1 
ATOM   11560 H HB3  . GLU B 1 413 ? -13.027 20.172  68.201 1.00 20.35 ?  379  GLU B HB3  1 
ATOM   11561 H HG2  . GLU B 1 413 ? -12.789 18.041  67.714 1.00 34.08 ?  379  GLU B HG2  1 
ATOM   11562 H HG3  . GLU B 1 413 ? -11.345 18.256  67.084 1.00 34.08 ?  379  GLU B HG3  1 
ATOM   11563 N N    . THR B 1 414 ? -14.696 20.446  65.777 1.00 14.23 ?  380  THR B N    1 
ATOM   11564 C CA   . THR B 1 414 ? -15.878 19.938  65.092 1.00 14.55 ?  380  THR B CA   1 
ATOM   11565 C C    . THR B 1 414 ? -16.241 20.762  63.874 1.00 19.87 ?  380  THR B C    1 
ATOM   11566 O O    . THR B 1 414 ? -17.191 20.409  63.167 1.00 17.61 ?  380  THR B O    1 
ATOM   11567 C CB   . THR B 1 414 ? -17.072 19.937  66.047 1.00 14.71 ?  380  THR B CB   1 
ATOM   11568 O OG1  . THR B 1 414 ? -17.258 21.246  66.582 1.00 16.55 ?  380  THR B OG1  1 
ATOM   11569 C CG2  . THR B 1 414 ? -16.842 18.939  67.181 1.00 21.56 ?  380  THR B CG2  1 
ATOM   11570 H H    . THR B 1 414 ? -14.861 21.088  66.325 1.00 17.08 ?  380  THR B H    1 
ATOM   11571 H HA   . THR B 1 414 ? -15.703 19.026  64.811 1.00 17.46 ?  380  THR B HA   1 
ATOM   11572 H HB   . THR B 1 414 ? -17.874 19.674  65.569 1.00 17.66 ?  380  THR B HB   1 
ATOM   11573 H HG1  . THR B 1 414 ? -17.436 21.786  65.965 1.00 19.86 ?  380  THR B HG1  1 
ATOM   11574 H HG21 . THR B 1 414 ? -17.638 18.872  67.731 1.00 25.88 ?  380  THR B HG21 1 
ATOM   11575 H HG22 . THR B 1 414 ? -16.636 18.064  66.817 1.00 25.88 ?  380  THR B HG22 1 
ATOM   11576 H HG23 . THR B 1 414 ? -16.101 19.231  67.735 1.00 25.88 ?  380  THR B HG23 1 
ATOM   11577 N N    . GLN B 1 415 ? -15.520 21.859  63.632 1.00 12.91 ?  381  GLN B N    1 
ATOM   11578 C CA   . GLN B 1 415 ? -15.817 22.783  62.539 1.00 14.35 ?  381  GLN B CA   1 
ATOM   11579 C C    . GLN B 1 415 ? -17.252 23.280  62.624 1.00 16.07 ?  381  GLN B C    1 
ATOM   11580 O O    . GLN B 1 415 ? -17.990 23.308  61.633 1.00 18.15 ?  381  GLN B O    1 
ATOM   11581 C CB   . GLN B 1 415 ? -15.533 22.160  61.171 1.00 17.82 ?  381  GLN B CB   1 
ATOM   11582 C CG   . GLN B 1 415 ? -14.088 21.920  60.933 1.00 19.14 ?  381  GLN B CG   1 
ATOM   11583 C CD   . GLN B 1 415 ? -13.775 21.558  59.503 1.00 23.76 ?  381  GLN B CD   1 
ATOM   11584 O OE1  . GLN B 1 415 ? -14.445 21.991  58.565 1.00 25.18 ?  381  GLN B OE1  1 
ATOM   11585 N NE2  . GLN B 1 415 ? -12.715 20.806  59.326 1.00 21.98 ?  381  GLN B NE2  1 
ATOM   11586 H H    . GLN B 1 415 ? -14.837 22.094  64.098 1.00 15.50 ?  381  GLN B H    1 
ATOM   11587 H HA   . GLN B 1 415 ? -15.231 23.549  62.633 1.00 17.22 ?  381  GLN B HA   1 
ATOM   11588 H HB2  . GLN B 1 415 ? -15.992 21.308  61.112 1.00 21.39 ?  381  GLN B HB2  1 
ATOM   11589 H HB3  . GLN B 1 415 ? -15.855 22.760  60.480 1.00 21.39 ?  381  GLN B HB3  1 
ATOM   11590 H HG2  . GLN B 1 415 ? -13.595 22.727  61.152 1.00 22.97 ?  381  GLN B HG2  1 
ATOM   11591 H HG3  . GLN B 1 415 ? -13.794 21.188  61.498 1.00 22.97 ?  381  GLN B HG3  1 
ATOM   11592 H HE21 . GLN B 1 415 ? -12.250 20.552  60.003 1.00 26.38 ?  381  GLN B HE21 1 
ATOM   11593 H HE22 . GLN B 1 415 ? -12.485 20.567  58.532 1.00 26.38 ?  381  GLN B HE22 1 
ATOM   11594 N N    . THR B 1 416 ? -17.648 23.683  63.818 1.00 13.32 ?  382  THR B N    1 
ATOM   11595 C CA   . THR B 1 416 ? -18.971 24.245  64.020 1.00 14.96 ?  382  THR B CA   1 
ATOM   11596 C C    . THR B 1 416 ? -18.878 25.530  64.826 1.00 15.11 ?  382  THR B C    1 
ATOM   11597 O O    . THR B 1 416 ? -17.926 25.772  65.577 1.00 13.88 ?  382  THR B O    1 
ATOM   11598 C CB   . THR B 1 416 ? -19.938 23.250  64.647 1.00 26.25 ?  382  THR B CB   1 
ATOM   11599 O OG1  . THR B 1 416 ? -19.434 22.826  65.904 1.00 24.16 ?  382  THR B OG1  1 
ATOM   11600 C CG2  . THR B 1 416 ? -20.102 22.040  63.733 1.00 29.86 ?  382  THR B CG2  1 
ATOM   11601 H H    . THR B 1 416 ? -17.167 23.642  64.529 1.00 15.98 ?  382  THR B H    1 
ATOM   11602 H HA   . THR B 1 416 ? -19.351 24.484  63.161 1.00 17.95 ?  382  THR B HA   1 
ATOM   11603 H HB   . THR B 1 416 ? -20.805 23.665  64.773 1.00 31.50 ?  382  THR B HB   1 
ATOM   11604 H HG1  . THR B 1 416 ? -19.962 22.275  66.254 1.00 28.99 ?  382  THR B HG1  1 
ATOM   11605 H HG21 . THR B 1 416 ? -20.726 21.410  64.126 1.00 35.83 ?  382  THR B HG21 1 
ATOM   11606 H HG22 . THR B 1 416 ? -20.440 22.321  62.868 1.00 35.83 ?  382  THR B HG22 1 
ATOM   11607 H HG23 . THR B 1 416 ? -19.247 21.600  63.609 1.00 35.83 ?  382  THR B HG23 1 
ATOM   11608 N N    . ALA B 1 417 ? -19.873 26.382  64.639 1.00 12.55 ?  383  ALA B N    1 
ATOM   11609 C CA   . ALA B 1 417 ? -19.949 27.614  65.382 1.00 12.17 ?  383  ALA B CA   1 
ATOM   11610 C C    . ALA B 1 417 ? -21.406 27.939  65.649 1.00 12.13 ?  383  ALA B C    1 
ATOM   11611 O O    . ALA B 1 417 ? -22.307 27.507  64.919 1.00 15.30 ?  383  ALA B O    1 
ATOM   11612 C CB   . ALA B 1 417 ? -19.291 28.775  64.626 1.00 12.50 ?  383  ALA B CB   1 
ATOM   11613 H H    . ALA B 1 417 ? -20.517 26.263  64.081 1.00 15.05 ?  383  ALA B H    1 
ATOM   11614 H HA   . ALA B 1 417 ? -19.494 27.498  66.231 1.00 14.60 ?  383  ALA B HA   1 
ATOM   11615 H HB1  . ALA B 1 417 ? -19.236 29.545  65.214 1.00 14.99 ?  383  ALA B HB1  1 
ATOM   11616 H HB2  . ALA B 1 417 ? -18.400 28.507  64.349 1.00 14.99 ?  383  ALA B HB2  1 
ATOM   11617 H HB3  . ALA B 1 417 ? -19.828 28.991  63.848 1.00 14.99 ?  383  ALA B HB3  1 
ATOM   11618 N N    . THR B 1 418 ? -21.622 28.744  66.682 1.00 10.95 ?  384  THR B N    1 
ATOM   11619 C CA   . THR B 1 418 ? -22.923 29.266  67.050 1.00 13.12 ?  384  THR B CA   1 
ATOM   11620 C C    . THR B 1 418 ? -22.816 30.778  67.098 1.00 14.67 ?  384  THR B C    1 
ATOM   11621 O O    . THR B 1 418 ? -21.995 31.329  67.847 1.00 14.88 ?  384  THR B O    1 
ATOM   11622 C CB   . THR B 1 418 ? -23.373 28.721  68.410 1.00 15.38 ?  384  THR B CB   1 
ATOM   11623 O OG1  . THR B 1 418 ? -23.412 27.292  68.358 1.00 14.93 ?  384  THR B OG1  1 
ATOM   11624 C CG2  . THR B 1 418 ? -24.739 29.270  68.776 1.00 19.34 ?  384  THR B CG2  1 
ATOM   11625 H H    . THR B 1 418 ? -20.996 29.013  67.207 1.00 13.14 ?  384  THR B H    1 
ATOM   11626 H HA   . THR B 1 418 ? -23.584 29.010  66.388 1.00 15.74 ?  384  THR B HA   1 
ATOM   11627 H HB   . THR B 1 418 ? -22.749 28.996  69.101 1.00 18.45 ?  384  THR B HB   1 
ATOM   11628 H HG1  . THR B 1 418 ? -23.725 26.986  69.075 1.00 17.91 ?  384  THR B HG1  1 
ATOM   11629 H HG21 . THR B 1 418 ? -25.021 28.913  69.632 1.00 23.20 ?  384  THR B HG21 1 
ATOM   11630 H HG22 . THR B 1 418 ? -24.703 30.237  68.834 1.00 23.20 ?  384  THR B HG22 1 
ATOM   11631 H HG23 . THR B 1 418 ? -25.388 29.019  68.100 1.00 23.20 ?  384  THR B HG23 1 
ATOM   11632 N N    . LEU B 1 419 ? -23.614 31.449  66.282 1.00 13.37 ?  385  LEU B N    1 
ATOM   11633 C CA   . LEU B 1 419 ? -23.735 32.894  66.306 1.00 12.48 ?  385  LEU B CA   1 
ATOM   11634 C C    . LEU B 1 419 ? -25.062 33.241  66.970 1.00 15.63 ?  385  LEU B C    1 
ATOM   11635 O O    . LEU B 1 419 ? -26.130 32.943  66.424 1.00 17.80 ?  385  LEU B O    1 
ATOM   11636 C CB   . LEU B 1 419 ? -23.673 33.453  64.889 1.00 12.48 ?  385  LEU B CB   1 
ATOM   11637 C CG   . LEU B 1 419 ? -22.405 33.174  64.101 1.00 12.73 ?  385  LEU B CG   1 
ATOM   11638 C CD1  . LEU B 1 419 ? -22.397 33.940  62.786 1.00 12.54 ?  385  LEU B CD1  1 
ATOM   11639 C CD2  . LEU B 1 419 ? -21.132 33.522  64.881 1.00 14.02 ?  385  LEU B CD2  1 
ATOM   11640 H H    . LEU B 1 419 ? -24.110 31.075  65.687 1.00 16.04 ?  385  LEU B H    1 
ATOM   11641 H HA   . LEU B 1 419 ? -23.012 33.281  66.824 1.00 14.98 ?  385  LEU B HA   1 
ATOM   11642 H HB2  . LEU B 1 419 ? -24.410 33.074  64.385 1.00 14.98 ?  385  LEU B HB2  1 
ATOM   11643 H HB3  . LEU B 1 419 ? -23.768 34.416  64.942 1.00 14.98 ?  385  LEU B HB3  1 
ATOM   11644 H HG   . LEU B 1 419 ? -22.397 32.220  63.925 1.00 15.27 ?  385  LEU B HG   1 
ATOM   11645 H HD11 . LEU B 1 419 ? -21.533 33.827  62.359 1.00 15.05 ?  385  LEU B HD11 1 
ATOM   11646 H HD12 . LEU B 1 419 ? -23.097 33.591  62.213 1.00 15.05 ?  385  LEU B HD12 1 
ATOM   11647 H HD13 . LEU B 1 419 ? -22.556 34.880  62.967 1.00 15.05 ?  385  LEU B HD13 1 
ATOM   11648 H HD21 . LEU B 1 419 ? -20.365 33.412  64.299 1.00 16.82 ?  385  LEU B HD21 1 
ATOM   11649 H HD22 . LEU B 1 419 ? -21.189 34.441  65.184 1.00 16.82 ?  385  LEU B HD22 1 
ATOM   11650 H HD23 . LEU B 1 419 ? -21.056 32.926  65.644 1.00 16.82 ?  385  LEU B HD23 1 
ATOM   11651 N N    . THR B 1 420 ? -24.997 33.859  68.150 1.00 13.92 ?  386  THR B N    1 
ATOM   11652 C CA   . THR B 1 420 ? -26.194 34.266  68.890 1.00 13.18 ?  386  THR B CA   1 
ATOM   11653 C C    . THR B 1 420 ? -26.392 35.759  68.697 1.00 13.89 ?  386  THR B C    1 
ATOM   11654 O O    . THR B 1 420 ? -25.809 36.575  69.410 1.00 14.97 ?  386  THR B O    1 
ATOM   11655 C CB   . THR B 1 420 ? -26.099 33.887  70.363 1.00 15.60 ?  386  THR B CB   1 
ATOM   11656 O OG1  . THR B 1 420 ? -25.814 32.489  70.455 1.00 17.44 ?  386  THR B OG1  1 
ATOM   11657 C CG2  . THR B 1 420 ? -27.428 34.170  71.063 1.00 15.86 ?  386  THR B CG2  1 
ATOM   11658 H H    . THR B 1 420 ? -24.261 34.056  68.549 1.00 16.71 ?  386  THR B H    1 
ATOM   11659 H HA   . THR B 1 420 ? -26.963 33.807  68.517 1.00 15.81 ?  386  THR B HA   1 
ATOM   11660 H HB   . THR B 1 420 ? -25.402 34.402  70.800 1.00 18.72 ?  386  THR B HB   1 
ATOM   11661 H HG1  . THR B 1 420 ? -25.046 32.332  70.153 1.00 20.93 ?  386  THR B HG1  1 
ATOM   11662 H HG21 . THR B 1 420 ? -27.389 33.866  71.984 1.00 19.03 ?  386  THR B HG21 1 
ATOM   11663 H HG22 . THR B 1 420 ? -27.612 35.122  71.054 1.00 19.03 ?  386  THR B HG22 1 
ATOM   11664 H HG23 . THR B 1 420 ? -28.148 33.705  70.609 1.00 19.03 ?  386  THR B HG23 1 
ATOM   11665 N N    . TRP B 1 421 ? -27.228 36.107  67.730 1.00 14.16 ?  387  TRP B N    1 
ATOM   11666 C CA   . TRP B 1 421 ? -27.496 37.496  67.429 1.00 14.53 ?  387  TRP B CA   1 
ATOM   11667 C C    . TRP B 1 421 ? -28.488 38.068  68.434 1.00 16.66 ?  387  TRP B C    1 
ATOM   11668 O O    . TRP B 1 421 ? -29.438 37.395  68.843 1.00 19.01 ?  387  TRP B O    1 
ATOM   11669 C CB   . TRP B 1 421 ? -28.077 37.605  66.023 1.00 12.92 ?  387  TRP B CB   1 
ATOM   11670 C CG   . TRP B 1 421 ? -27.194 37.059  64.934 1.00 12.88 ?  387  TRP B CG   1 
ATOM   11671 C CD1  . TRP B 1 421 ? -27.236 35.808  64.397 1.00 13.48 ?  387  TRP B CD1  1 
ATOM   11672 C CD2  . TRP B 1 421 ? -26.149 37.762  64.237 1.00 12.64 ?  387  TRP B CD2  1 
ATOM   11673 N NE1  . TRP B 1 421 ? -26.288 35.680  63.397 1.00 13.05 ?  387  TRP B NE1  1 
ATOM   11674 C CE2  . TRP B 1 421 ? -25.615 36.869  63.280 1.00 12.63 ?  387  TRP B CE2  1 
ATOM   11675 C CE3  . TRP B 1 421 ? -25.619 39.053  64.322 1.00 12.05 ?  387  TRP B CE3  1 
ATOM   11676 C CZ2  . TRP B 1 421 ? -24.572 37.228  62.421 1.00 12.08 ?  387  TRP B CZ2  1 
ATOM   11677 C CZ3  . TRP B 1 421 ? -24.586 39.406  63.453 1.00 12.84 ?  387  TRP B CZ3  1 
ATOM   11678 C CH2  . TRP B 1 421 ? -24.077 38.488  62.522 1.00 11.81 ?  387  TRP B CH2  1 
ATOM   11679 H H    . TRP B 1 421 ? -27.653 35.550  67.232 1.00 16.99 ?  387  TRP B H    1 
ATOM   11680 H HA   . TRP B 1 421 ? -26.677 38.013  67.476 1.00 17.44 ?  387  TRP B HA   1 
ATOM   11681 H HB2  . TRP B 1 421 ? -28.912 37.113  65.996 1.00 15.50 ?  387  TRP B HB2  1 
ATOM   11682 H HB3  . TRP B 1 421 ? -28.236 38.541  65.827 1.00 15.50 ?  387  TRP B HB3  1 
ATOM   11683 H HD1  . TRP B 1 421 ? -27.820 35.135  64.663 1.00 16.18 ?  387  TRP B HD1  1 
ATOM   11684 H HE1  . TRP B 1 421 ? -26.144 34.974  62.929 1.00 15.66 ?  387  TRP B HE1  1 
ATOM   11685 H HE3  . TRP B 1 421 ? -25.947 39.663  64.943 1.00 14.46 ?  387  TRP B HE3  1 
ATOM   11686 H HZ2  . TRP B 1 421 ? -24.230 36.625  61.802 1.00 14.49 ?  387  TRP B HZ2  1 
ATOM   11687 H HZ3  . TRP B 1 421 ? -24.230 40.264  63.492 1.00 15.41 ?  387  TRP B HZ3  1 
ATOM   11688 H HH2  . TRP B 1 421 ? -23.383 38.749  61.960 1.00 14.17 ?  387  TRP B HH2  1 
ATOM   11689 N N    . LYS B 1 422 ? -28.280 39.324  68.794 1.00 16.51 ?  388  LYS B N    1 
ATOM   11690 C CA   . LYS B 1 422 ? -29.125 40.041  69.750 1.00 23.01 ?  388  LYS B CA   1 
ATOM   11691 C C    . LYS B 1 422 ? -29.857 41.178  69.044 1.00 33.58 ?  388  LYS B C    1 
ATOM   11692 O O    . LYS B 1 422 ? -29.275 41.913  68.240 1.00 25.25 ?  388  LYS B O    1 
ATOM   11693 C CB   . LYS B 1 422 ? -28.237 40.575  70.882 1.00 28.26 ?  388  LYS B CB   1 
ATOM   11694 C CG   . LYS B 1 422 ? -28.827 41.681  71.738 1.00 45.20 ?  388  LYS B CG   1 
ATOM   11695 C CD   . LYS B 1 422 ? -27.818 42.197  72.795 1.00 47.13 ?  388  LYS B CD   1 
ATOM   11696 C CE   . LYS B 1 422 ? -26.759 41.159  73.203 1.00 37.06 ?  388  LYS B CE   1 
ATOM   11697 N NZ   . LYS B 1 422 ? -26.140 41.436  74.543 1.00 38.36 ?  388  LYS B NZ   1 
ATOM   11698 H H    . LYS B 1 422 ? -27.635 39.805  68.490 1.00 19.81 ?  388  LYS B H    1 
ATOM   11699 H HA   . LYS B 1 422 ? -29.796 39.458  70.138 1.00 27.61 ?  388  LYS B HA   1 
ATOM   11700 H HB2  . LYS B 1 422 ? -28.028 39.836  71.475 1.00 33.91 ?  388  LYS B HB2  1 
ATOM   11701 H HB3  . LYS B 1 422 ? -27.422 40.924  70.487 1.00 33.91 ?  388  LYS B HB3  1 
ATOM   11702 H HG2  . LYS B 1 422 ? -29.078 42.426  71.169 1.00 54.25 ?  388  LYS B HG2  1 
ATOM   11703 H HG3  . LYS B 1 422 ? -29.608 41.343  72.204 1.00 54.25 ?  388  LYS B HG3  1 
ATOM   11704 H HD2  . LYS B 1 422 ? -27.352 42.967  72.432 1.00 56.55 ?  388  LYS B HD2  1 
ATOM   11705 H HD3  . LYS B 1 422 ? -28.305 42.451  73.594 1.00 56.55 ?  388  LYS B HD3  1 
ATOM   11706 H HE2  . LYS B 1 422 ? -27.175 40.284  73.242 1.00 44.48 ?  388  LYS B HE2  1 
ATOM   11707 H HE3  . LYS B 1 422 ? -26.048 41.158  72.542 1.00 44.48 ?  388  LYS B HE3  1 
ATOM   11708 H HZ1  . LYS B 1 422 ? -25.535 40.812  74.734 1.00 46.03 ?  388  LYS B HZ1  1 
ATOM   11709 H HZ2  . LYS B 1 422 ? -25.742 42.232  74.535 1.00 46.03 ?  388  LYS B HZ2  1 
ATOM   11710 H HZ3  . LYS B 1 422 ? -26.768 41.433  75.174 1.00 46.03 ?  388  LYS B HZ3  1 
HETATM 11711 C C5   . X6Y C 2 .   ? -11.291 14.718  28.514 1.00 20.00 ?  1    X6Y C C5   1 
HETATM 11712 C C6   . X6Y C 2 .   ? -10.647 13.660  27.691 1.00 20.00 ?  1    X6Y C C6   1 
HETATM 11713 C C2   . X6Y C 2 .   ? -12.667 17.204  28.432 1.00 20.00 ?  1    X6Y C C2   1 
HETATM 11714 C C4   . X6Y C 2 .   ? -10.543 16.050  28.415 1.00 20.00 ?  1    X6Y C C4   1 
HETATM 11715 C C3   . X6Y C 2 .   ? -11.331 17.090  29.094 1.00 20.00 ?  1    X6Y C C3   1 
HETATM 11716 C C1   . X6Y C 2 .   ? -13.438 15.914  28.599 1.00 20.00 ?  1    X6Y C C1   1 
HETATM 11717 O O5   . X6Y C 2 .   ? -12.697 14.805  28.037 1.00 20.00 ?  1    X6Y C O5   1 
HETATM 11718 O O4   . X6Y C 2 .   ? -10.330 16.430  27.038 1.00 20.00 ?  1    X6Y C O4   1 
HETATM 11719 O O1   . X6Y C 2 .   ? -13.610 15.694  29.938 1.00 20.00 ?  1    X6Y C O1   1 
HETATM 11720 O O3   . X6Y C 2 .   ? -10.641 18.371  29.058 1.00 20.00 ?  1    X6Y C O3   1 
HETATM 11721 S S1   . X6Y C 2 .   ? -14.407 19.133  28.073 1.00 20.00 ?  1    X6Y C S1   1 
HETATM 11722 O O6   . X6Y C 2 .   ? -15.682 18.380  27.842 1.00 20.00 ?  1    X6Y C O6   1 
HETATM 11723 O O7   . X6Y C 2 .   ? -13.700 19.496  26.816 1.00 20.00 -1 1    X6Y C O7   1 
HETATM 11724 O O8   . X6Y C 2 .   ? -14.756 20.335  28.887 1.00 20.00 ?  1    X6Y C O8   1 
HETATM 11725 O O2   . X6Y C 2 .   ? -13.423 18.229  29.044 1.00 20.00 ?  1    X6Y C O2   1 
HETATM 11726 H H5   . X6Y C 2 .   ? -11.295 14.409  29.551 1.00 20.00 ?  1    X6Y C H5   1 
HETATM 11727 H H61  . X6Y C 2 .   ? -11.042 13.710  26.680 1.00 20.00 ?  1    X6Y C H61  1 
HETATM 11728 H H63  . X6Y C 2 .   ? -9.576  13.831  27.672 1.00 20.00 ?  1    X6Y C H63  1 
HETATM 11729 H H62  . X6Y C 2 .   ? -10.859 12.687  28.121 1.00 20.00 ?  1    X6Y C H62  1 
HETATM 11730 H H2   . X6Y C 2 .   ? -12.544 17.410  27.379 1.00 20.00 ?  1    X6Y C H2   1 
HETATM 11731 H H4   . X6Y C 2 .   ? -9.587  15.959  28.916 1.00 20.00 ?  1    X6Y C H4   1 
HETATM 11732 H H3   . X6Y C 2 .   ? -11.468 16.793  30.124 1.00 20.00 ?  1    X6Y C H3   1 
HETATM 11733 H H1   . X6Y C 2 .   ? -14.398 16.003  28.109 1.00 20.00 ?  1    X6Y C H1   1 
HETATM 11734 H HO4  . X6Y C 2 .   ? -11.012 16.057  26.503 1.00 20.00 ?  1    X6Y C HO4  1 
HETATM 11735 H HO1  . X6Y C 2 .   ? -13.711 16.523  30.376 1.00 20.00 ?  1    X6Y C HO1  1 
HETATM 11736 C C5   . X6Y C 2 .   ? -11.673 20.324  30.812 1.00 20.00 ?  2    X6Y C C5   1 
HETATM 11737 C C6   . X6Y C 2 .   ? -12.690 20.639  31.839 1.00 20.00 ?  2    X6Y C C6   1 
HETATM 11738 C C2   . X6Y C 2 .   ? -8.994  19.686  30.133 1.00 20.00 ?  2    X6Y C C2   1 
HETATM 11739 C C4   . X6Y C 2 .   ? -10.643 21.429  30.686 1.00 20.00 ?  2    X6Y C C4   1 
HETATM 11740 C C3   . X6Y C 2 .   ? -9.561  21.018  29.779 1.00 20.00 ?  2    X6Y C C3   1 
HETATM 11741 C C1   . X6Y C 2 .   ? -10.057 18.605  30.275 1.00 20.00 ?  2    X6Y C C1   1 
HETATM 11742 O O5   . X6Y C 2 .   ? -11.035 19.054  31.243 1.00 20.00 ?  2    X6Y C O5   1 
HETATM 11743 O O4   . X6Y C 2 .   ? -10.094 21.696  31.990 1.00 20.00 ?  2    X6Y C O4   1 
HETATM 11744 O O3   . X6Y C 2 .   ? -8.453  21.934  29.899 1.00 20.00 ?  2    X6Y C O3   1 
HETATM 11745 S S1   . X6Y C 2 .   ? -6.824  18.399  29.507 1.00 20.00 ?  2    X6Y C S1   1 
HETATM 11746 O O6   . X6Y C 2 .   ? -6.155  18.048  28.217 1.00 20.00 ?  2    X6Y C O6   1 
HETATM 11747 O O7   . X6Y C 2 .   ? -6.004  19.187  30.483 1.00 20.00 -1 2    X6Y C O7   1 
HETATM 11748 O O8   . X6Y C 2 .   ? -7.318  17.125  30.126 1.00 20.00 ?  2    X6Y C O8   1 
HETATM 11749 O O2   . X6Y C 2 .   ? -8.123  19.322  29.086 1.00 20.00 ?  2    X6Y C O2   1 
HETATM 11750 H H5   . X6Y C 2 .   ? -12.154 20.191  29.854 1.00 20.00 ?  2    X6Y C H5   1 
HETATM 11751 H H61  . X6Y C 2 .   ? -12.833 21.713  31.878 1.00 20.00 ?  2    X6Y C H61  1 
HETATM 11752 H H63  . X6Y C 2 .   ? -12.343 20.280  32.804 1.00 20.00 ?  2    X6Y C H63  1 
HETATM 11753 H H62  . X6Y C 2 .   ? -13.624 20.151  31.577 1.00 20.00 ?  2    X6Y C H62  1 
HETATM 11754 H H2   . X6Y C 2 .   ? -8.445  19.771  31.061 1.00 20.00 ?  2    X6Y C H2   1 
HETATM 11755 H H4   . X6Y C 2 .   ? -11.114 22.321  30.297 1.00 20.00 ?  2    X6Y C H4   1 
HETATM 11756 H H3   . X6Y C 2 .   ? -9.924  21.000  28.760 1.00 20.00 ?  2    X6Y C H3   1 
HETATM 11757 H H1   . X6Y C 2 .   ? -9.603  17.696  30.639 1.00 20.00 ?  2    X6Y C H1   1 
HETATM 11758 H HO4  . X6Y C 2 .   ? -9.971  20.880  32.447 1.00 20.00 ?  2    X6Y C HO4  1 
HETATM 11759 C C1   . FUC C 2 .   ? -8.538  23.077  29.158 1.00 20.00 ?  3    FUC C C1   1 
HETATM 11760 C C2   . FUC C 2 .   ? -8.086  24.229  30.041 1.00 20.00 ?  3    FUC C C2   1 
HETATM 11761 C C3   . FUC C 2 .   ? -6.673  24.071  30.433 1.00 20.00 ?  3    FUC C C3   1 
HETATM 11762 C C4   . FUC C 2 .   ? -5.787  23.982  29.253 1.00 20.00 ?  3    FUC C C4   1 
HETATM 11763 C C5   . FUC C 2 .   ? -6.267  22.805  28.408 1.00 20.00 ?  3    FUC C C5   1 
HETATM 11764 C C6   . FUC C 2 .   ? -5.463  22.655  27.158 1.00 20.00 ?  3    FUC C C6   1 
HETATM 11765 O O2   . FUC C 2 .   ? -8.918  24.227  31.209 1.00 20.00 ?  3    FUC C O2   1 
HETATM 11766 O O3   . FUC C 2 .   ? -6.308  25.205  31.301 1.00 20.00 ?  3    FUC C O3   1 
HETATM 11767 O O4   . FUC C 2 .   ? -5.823  25.190  28.475 1.00 20.00 ?  3    FUC C O4   1 
HETATM 11768 O O5   . FUC C 2 .   ? -7.656  23.002  28.009 1.00 20.00 ?  3    FUC C O5   1 
HETATM 11769 H H1   . FUC C 2 .   ? -9.555  23.239  28.838 1.00 20.00 ?  3    FUC C H1   1 
HETATM 11770 H H2   . FUC C 2 .   ? -8.207  25.158  29.504 1.00 20.00 ?  3    FUC C H2   1 
HETATM 11771 H H3   . FUC C 2 .   ? -6.602  23.139  30.976 1.00 20.00 ?  3    FUC C H3   1 
HETATM 11772 H H4   . FUC C 2 .   ? -4.775  23.788  29.583 1.00 20.00 ?  3    FUC C H4   1 
HETATM 11773 H H5   . FUC C 2 .   ? -6.182  21.898  28.993 1.00 20.00 ?  3    FUC C H5   1 
HETATM 11774 H H61  . FUC C 2 .   ? -5.892  23.284  26.385 1.00 20.00 ?  3    FUC C H61  1 
HETATM 11775 H H62  . FUC C 2 .   ? -4.442  22.964  27.356 1.00 20.00 ?  3    FUC C H62  1 
HETATM 11776 H H63  . FUC C 2 .   ? -5.480  21.617  26.841 1.00 20.00 ?  3    FUC C H63  1 
HETATM 11777 H HO2  . FUC C 2 .   ? -8.824  23.396  31.646 1.00 20.00 ?  3    FUC C HO2  1 
HETATM 11778 H HO4  . FUC C 2 .   ? -6.538  25.137  27.862 1.00 20.00 ?  3    FUC C HO4  1 
HETATM 11779 C C5   . X2Y C 2 .   ? -5.931  23.356  33.626 1.00 20.00 ?  4    X2Y C C5   1 
HETATM 11780 C C4   . X2Y C 2 .   ? -5.615  24.272  34.784 1.00 20.00 ?  4    X2Y C C4   1 
HETATM 11781 C C3   . X2Y C 2 .   ? -5.955  25.620  34.329 1.00 20.00 ?  4    X2Y C C3   1 
HETATM 11782 C C2   . X2Y C 2 .   ? -5.113  26.029  33.189 1.00 20.00 ?  4    X2Y C C2   1 
HETATM 11783 C C1   . X2Y C 2 .   ? -5.134  25.035  32.019 1.00 20.00 ?  4    X2Y C C1   1 
HETATM 11784 O O5   . X2Y C 2 .   ? -4.986  23.680  32.541 1.00 20.00 ?  4    X2Y C O5   1 
HETATM 11785 C C6   . X2Y C 2 .   ? -5.765  21.937  34.021 1.00 20.00 ?  4    X2Y C C6   1 
HETATM 11786 O O3   . X2Y C 2 .   ? -5.708  26.596  35.384 1.00 20.00 ?  4    X2Y C O3   1 
HETATM 11787 S S1   . X2Y C 2 .   ? -4.537  28.291  32.118 1.00 20.00 ?  4    X2Y C S1   1 
HETATM 11788 O O6   . X2Y C 2 .   ? -5.250  29.343  31.306 1.00 20.00 ?  4    X2Y C O6   1 
HETATM 11789 O O7   . X2Y C 2 .   ? -3.787  28.840  33.274 1.00 20.00 -1 4    X2Y C O7   1 
HETATM 11790 O O8   . X2Y C 2 .   ? -3.722  27.507  31.146 1.00 20.00 ?  4    X2Y C O8   1 
HETATM 11791 O O2   . X2Y C 2 .   ? -5.633  27.275  32.761 1.00 20.00 ?  4    X2Y C O2   1 
HETATM 11792 S S2   . X2Y C 2 .   ? -3.640  23.794  36.563 1.00 20.00 ?  4    X2Y C S2   1 
HETATM 11793 O O9   . X2Y C 2 .   ? -2.166  24.006  36.603 1.00 20.00 ?  4    X2Y C O9   1 
HETATM 11794 O O10  . X2Y C 2 .   ? -4.376  24.631  37.554 1.00 20.00 -1 4    X2Y C O10  1 
HETATM 11795 O O11  . X2Y C 2 .   ? -3.745  22.326  36.826 1.00 20.00 ?  4    X2Y C O11  1 
HETATM 11796 O O4   . X2Y C 2 .   ? -4.211  24.184  35.064 1.00 20.00 ?  4    X2Y C O4   1 
HETATM 11797 H H5   . X2Y C 2 .   ? -6.944  23.531  33.285 1.00 20.00 ?  4    X2Y C H5   1 
HETATM 11798 H H4   . X2Y C 2 .   ? -6.203  24.006  35.652 1.00 20.00 ?  4    X2Y C H4   1 
HETATM 11799 H H3   . X2Y C 2 .   ? -6.995  25.644  34.032 1.00 20.00 ?  4    X2Y C H3   1 
HETATM 11800 H H2   . X2Y C 2 .   ? -4.094  26.161  33.527 1.00 20.00 ?  4    X2Y C H2   1 
HETATM 11801 H H1   . X2Y C 2 .   ? -4.294  25.245  31.369 1.00 20.00 ?  4    X2Y C H1   1 
HETATM 11802 H H61  . X2Y C 2 .   ? -4.752  21.621  33.791 1.00 20.00 ?  4    X2Y C H61  1 
HETATM 11803 H H63  . X2Y C 2 .   ? -6.475  21.326  33.472 1.00 20.00 ?  4    X2Y C H63  1 
HETATM 11804 H H62  . X2Y C 2 .   ? -5.942  21.842  35.088 1.00 20.00 ?  4    X2Y C H62  1 
HETATM 11805 H HO3  . X2Y C 2 .   ? -5.306  26.156  36.116 1.00 20.00 ?  4    X2Y C HO3  1 
HETATM 11806 C C5   . X6Y D 2 .   ? -5.022  34.702  44.590 1.00 20.00 ?  1    X6Y D C5   1 
HETATM 11807 C C6   . X6Y D 2 .   ? -5.500  36.016  45.110 1.00 20.00 ?  1    X6Y D C6   1 
HETATM 11808 C C2   . X6Y D 2 .   ? -3.043  33.422  42.926 1.00 20.00 ?  1    X6Y D C2   1 
HETATM 11809 C C4   . X6Y D 2 .   ? -5.249  34.558  43.086 1.00 20.00 ?  1    X6Y D C4   1 
HETATM 11810 C C3   . X6Y D 2 .   ? -4.516  33.380  42.545 1.00 20.00 ?  1    X6Y D C3   1 
HETATM 11811 C C1   . X6Y D 2 .   ? -2.870  33.470  44.429 1.00 20.00 ?  1    X6Y D C1   1 
HETATM 11812 O O5   . X6Y D 2 .   ? -3.579  34.624  44.963 1.00 20.00 ?  1    X6Y D O5   1 
HETATM 11813 O O4   . X6Y D 2 .   ? -4.773  35.718  42.385 1.00 20.00 ?  1    X6Y D O4   1 
HETATM 11814 O O1   . X6Y D 2 .   ? -3.358  32.314  44.969 1.00 20.00 ?  1    X6Y D O1   1 
HETATM 11815 O O3   . X6Y D 2 .   ? -4.826  33.008  41.166 1.00 20.00 ?  1    X6Y D O3   1 
HETATM 11816 S S1   . X6Y D 2 .   ? -0.880  32.512  41.841 1.00 20.00 ?  1    X6Y D S1   1 
HETATM 11817 O O6   . X6Y D 2 .   ? -0.604  31.279  41.034 1.00 20.00 ?  1    X6Y D O6   1 
HETATM 11818 O O7   . X6Y D 2 .   ? 0.091   32.679  42.966 1.00 20.00 -1 1    X6Y D O7   1 
HETATM 11819 O O8   . X6Y D 2 .   ? -0.863  33.675  40.913 1.00 20.00 ?  1    X6Y D O8   1 
HETATM 11820 O O2   . X6Y D 2 .   ? -2.396  32.272  42.432 1.00 20.00 ?  1    X6Y D O2   1 
HETATM 11821 H H5   . X6Y D 2 .   ? -5.555  33.909  45.096 1.00 20.00 ?  1    X6Y D H5   1 
HETATM 11822 H H61  . X6Y D 2 .   ? -6.548  36.141  44.853 1.00 20.00 ?  1    X6Y D H61  1 
HETATM 11823 H H63  . X6Y D 2 .   ? -5.382  36.032  46.188 1.00 20.00 ?  1    X6Y D H63  1 
HETATM 11824 H H62  . X6Y D 2 .   ? -4.916  36.824  44.677 1.00 20.00 ?  1    X6Y D H62  1 
HETATM 11825 H H2   . X6Y D 2 .   ? -2.526  34.282  42.526 1.00 20.00 ?  1    X6Y D H2   1 
HETATM 11826 H H4   . X6Y D 2 .   ? -6.309  34.436  42.894 1.00 20.00 ?  1    X6Y D H4   1 
HETATM 11827 H H3   . X6Y D 2 .   ? -4.182  34.107  41.832 1.00 20.00 ?  1    X6Y D H3   1 
HETATM 11828 H H1   . X6Y D 2 .   ? -1.821  33.563  44.657 1.00 20.00 ?  1    X6Y D H1   1 
HETATM 11829 H HO4  . X6Y D 2 .   ? -5.331  36.454  42.560 1.00 20.00 ?  1    X6Y D HO4  1 
HETATM 11830 H HO1  . X6Y D 2 .   ? -3.315  31.628  44.322 1.00 20.00 ?  1    X6Y D HO1  1 
HETATM 11831 C C5   . X6Y D 2 .   ? -4.038  30.503  40.250 1.00 20.00 ?  2    X6Y D C5   1 
HETATM 11832 C C6   . X6Y D 2 .   ? -3.433  29.206  40.612 1.00 20.00 ?  2    X6Y D C6   1 
HETATM 11833 C C2   . X6Y D 2 .   ? -6.314  32.086  39.614 1.00 20.00 ?  2    X6Y D C2   1 
HETATM 11834 C C4   . X6Y D 2 .   ? -4.603  30.480  38.840 1.00 20.00 ?  2    X6Y D C4   1 
HETATM 11835 C C3   . X6Y D 2 .   ? -5.327  31.730  38.552 1.00 20.00 ?  2    X6Y D C3   1 
HETATM 11836 C C1   . X6Y D 2 .   ? -5.750  32.018  41.031 1.00 20.00 ?  2    X6Y D C1   1 
HETATM 11837 O O5   . X6Y D 2 .   ? -5.117  30.738  41.242 1.00 20.00 ?  2    X6Y D O5   1 
HETATM 11838 O O4   . X6Y D 2 .   ? -5.502  29.365  38.723 1.00 20.00 ?  2    X6Y D O4   1 
HETATM 11839 O O3   . X6Y D 2 .   ? -6.104  31.565  37.342 1.00 20.00 ?  2    X6Y D O3   1 
HETATM 11840 S S1   . X6Y D 2 .   ? -8.267  33.815  39.776 1.00 20.00 ?  2    X6Y D S1   1 
HETATM 11841 O O6   . X6Y D 2 .   ? -8.434  33.605  41.238 1.00 20.00 ?  2    X6Y D O6   1 
HETATM 11842 O O7   . X6Y D 2 .   ? -9.176  32.932  38.996 1.00 20.00 -1 2    X6Y D O7   1 
HETATM 11843 O O8   . X6Y D 2 .   ? -8.453  35.271  39.491 1.00 20.00 ?  2    X6Y D O8   1 
HETATM 11844 O O2   . X6Y D 2 .   ? -6.709  33.423  39.377 1.00 20.00 ?  2    X6Y D O2   1 
HETATM 11845 H H5   . X6Y D 2 .   ? -3.290  31.281  40.312 1.00 20.00 ?  2    X6Y D H5   1 
HETATM 11846 H H61  . X6Y D 2 .   ? -2.625  29.376  41.314 1.00 20.00 ?  2    X6Y D H61  1 
HETATM 11847 H H63  . X6Y D 2 .   ? -3.046  28.730  39.715 1.00 20.00 ?  2    X6Y D H63  1 
HETATM 11848 H H62  . X6Y D 2 .   ? -4.189  28.574  41.068 1.00 20.00 ?  2    X6Y D H62  1 
HETATM 11849 H H2   . X6Y D 2 .   ? -7.166  31.424  39.535 1.00 20.00 ?  2    X6Y D H2   1 
HETATM 11850 H H4   . X6Y D 2 .   ? -3.792  30.369  38.134 1.00 20.00 ?  2    X6Y D H4   1 
HETATM 11851 H H3   . X6Y D 2 .   ? -4.619  32.541  38.430 1.00 20.00 ?  2    X6Y D H3   1 
HETATM 11852 H H1   . X6Y D 2 .   ? -6.538  32.149  41.759 1.00 20.00 ?  2    X6Y D H1   1 
HETATM 11853 H HO4  . X6Y D 2 .   ? -6.156  29.569  38.073 1.00 20.00 ?  2    X6Y D HO4  1 
HETATM 11854 C C1   . FUC D 2 .   ? -5.419  31.793  36.186 1.00 20.00 ?  3    FUC D C1   1 
HETATM 11855 C C2   . FUC D 2 .   ? -5.895  30.781  35.151 1.00 20.00 ?  3    FUC D C2   1 
HETATM 11856 C C3   . FUC D 2 .   ? -7.317  30.981  34.794 1.00 20.00 ?  3    FUC D C3   1 
HETATM 11857 C C4   . FUC D 2 .   ? -7.575  32.366  34.355 1.00 20.00 ?  3    FUC D C4   1 
HETATM 11858 C C5   . FUC D 2 .   ? -7.114  33.313  35.457 1.00 20.00 ?  3    FUC D C5   1 
HETATM 11859 C C6   . FUC D 2 .   ? -7.342  34.742  35.083 1.00 20.00 ?  3    FUC D C6   1 
HETATM 11860 O O2   . FUC D 2 .   ? -5.670  29.483  35.720 1.00 20.00 ?  3    FUC D O2   1 
HETATM 11861 O O3   . FUC D 2 .   ? -7.631  30.038  33.715 1.00 20.00 ?  3    FUC D O3   1 
HETATM 11862 O O4   . FUC D 2 .   ? -6.887  32.609  33.110 1.00 20.00 ?  3    FUC D O4   1 
HETATM 11863 O O5   . FUC D 2 .   ? -5.690  33.134  35.688 1.00 20.00 ?  3    FUC D O5   1 
HETATM 11864 H H1   . FUC D 2 .   ? -4.360  31.674  36.352 1.00 20.00 ?  3    FUC D H1   1 
HETATM 11865 H H2   . FUC D 2 .   ? -5.294  30.890  34.259 1.00 20.00 ?  3    FUC D H2   1 
HETATM 11866 H H3   . FUC D 2 .   ? -7.934  30.768  35.658 1.00 20.00 ?  3    FUC D H3   1 
HETATM 11867 H H4   . FUC D 2 .   ? -8.634  32.543  34.232 1.00 20.00 ?  3    FUC D H4   1 
HETATM 11868 H H5   . FUC D 2 .   ? -7.673  33.099  36.359 1.00 20.00 ?  3    FUC D H5   1 
HETATM 11869 H H61  . FUC D 2 .   ? -8.284  34.828  34.548 1.00 20.00 ?  3    FUC D H61  1 
HETATM 11870 H H62  . FUC D 2 .   ? -7.383  35.348  35.984 1.00 20.00 ?  3    FUC D H62  1 
HETATM 11871 H H63  . FUC D 2 .   ? -6.531  35.088  34.450 1.00 20.00 ?  3    FUC D H63  1 
HETATM 11872 H HO2  . FUC D 2 .   ? -6.501  29.058  35.860 1.00 20.00 ?  3    FUC D HO2  1 
HETATM 11873 H HO4  . FUC D 2 .   ? -6.837  31.798  32.630 1.00 20.00 ?  3    FUC D HO4  1 
HETATM 11874 C C5   . X2Y D 2 .   ? -9.144  27.795  34.469 1.00 20.00 ?  4    X2Y D C5   1 
HETATM 11875 C C4   . X2Y D 2 .   ? -9.458  27.174  33.126 1.00 20.00 ?  4    X2Y D C4   1 
HETATM 11876 C C3   . X2Y D 2 .   ? -8.843  27.936  32.025 1.00 20.00 ?  4    X2Y D C3   1 
HETATM 11877 C C2   . X2Y D 2 .   ? -9.237  29.356  32.078 1.00 20.00 ?  4    X2Y D C2   1 
HETATM 11878 C C1   . X2Y D 2 .   ? -8.978  29.977  33.453 1.00 20.00 ?  4    X2Y D C1   1 
HETATM 11879 O O5   . X2Y D 2 .   ? -9.594  29.201  34.503 1.00 20.00 ?  4    X2Y D O5   1 
HETATM 11880 C C6   . X2Y D 2 .   ? -9.893  27.132  35.551 1.00 20.00 ?  4    X2Y D C6   1 
HETATM 11881 O O3   . X2Y D 2 .   ? -9.308  27.454  30.727 1.00 20.00 ?  4    X2Y D O3   1 
HETATM 11882 S S1   . X2Y D 2 .   ? -9.242  31.129  30.170 1.00 20.00 ?  4    X2Y D S1   1 
HETATM 11883 O O6   . X2Y D 2 .   ? -10.273 31.915  30.903 1.00 20.00 ?  4    X2Y D O6   1 
HETATM 11884 O O7   . X2Y D 2 .   ? -8.230  32.076  29.644 1.00 20.00 ?  4    X2Y D O7   1 
HETATM 11885 O O8   . X2Y D 2 .   ? -9.856  30.318  29.078 1.00 20.00 -1 4    X2Y D O8   1 
HETATM 11886 O O2   . X2Y D 2 .   ? -8.458  30.057  31.128 1.00 20.00 ?  4    X2Y D O2   1 
HETATM 11887 S S2   . X2Y D 2 .   ? -11.673 25.757  32.857 1.00 20.00 ?  4    X2Y D S2   1 
HETATM 11888 O O9   . X2Y D 2 .   ? -11.049 24.688  33.693 1.00 20.00 ?  4    X2Y D O9   1 
HETATM 11889 O O10  . X2Y D 2 .   ? -13.052 25.948  33.358 1.00 20.00 -1 4    X2Y D O10  1 
HETATM 11890 O O11  . X2Y D 2 .   ? -11.568 25.328  31.420 1.00 20.00 ?  4    X2Y D O11  1 
HETATM 11891 O O4   . X2Y D 2 .   ? -10.886 27.197  32.998 1.00 20.00 ?  4    X2Y D O4   1 
HETATM 11892 H H5   . X2Y D 2 .   ? -8.081  27.741  34.665 1.00 20.00 ?  4    X2Y D H5   1 
HETATM 11893 H H4   . X2Y D 2 .   ? -9.094  26.156  33.103 1.00 20.00 ?  4    X2Y D H4   1 
HETATM 11894 H H3   . X2Y D 2 .   ? -7.766  27.861  32.090 1.00 20.00 ?  4    X2Y D H3   1 
HETATM 11895 H H2   . X2Y D 2 .   ? -10.286 29.444  31.831 1.00 20.00 ?  4    X2Y D H2   1 
HETATM 11896 H H1   . X2Y D 2 .   ? -9.444  30.948  33.438 1.00 20.00 ?  4    X2Y D H1   1 
HETATM 11897 H H61  . X2Y D 2 .   ? -10.895 27.544  35.576 1.00 20.00 ?  4    X2Y D H61  1 
HETATM 11898 H H63  . X2Y D 2 .   ? -9.409  27.316  36.502 1.00 20.00 ?  4    X2Y D H63  1 
HETATM 11899 H H62  . X2Y D 2 .   ? -9.931  26.065  35.368 1.00 20.00 ?  4    X2Y D H62  1 
HETATM 11900 H HO3  . X2Y D 2 .   ? -9.984  26.810  30.864 1.00 20.00 ?  4    X2Y D HO3  1 
HETATM 11901 O O    . HOH E 3 .   ? -4.136  8.634   8.325  1.00 4.42  ?  401  HOH A O    1 
HETATM 11902 O O    . HOH E 3 .   ? -28.672 5.208   33.109 1.00 7.48  ?  402  HOH A O    1 
HETATM 11903 O O    . HOH E 3 .   ? -2.667  -3.151  14.502 1.00 33.68 ?  403  HOH A O    1 
HETATM 11904 O O    . HOH E 3 .   ? -26.722 -1.720  45.240 1.00 43.19 ?  404  HOH A O    1 
HETATM 11905 O O    . HOH E 3 .   ? -16.393 4.620   3.877  1.00 29.99 ?  405  HOH A O    1 
HETATM 11906 O O    . HOH E 3 .   ? -13.954 12.378  38.248 1.00 34.64 ?  406  HOH A O    1 
HETATM 11907 O O    . HOH E 3 .   ? -12.124 -12.554 27.799 1.00 23.08 ?  407  HOH A O    1 
HETATM 11908 O O    . HOH E 3 .   ? -30.269 0.606   16.694 1.00 43.44 ?  408  HOH A O    1 
HETATM 11909 O O    . HOH E 3 .   ? -13.993 -0.153  9.721  1.00 29.79 ?  409  HOH A O    1 
HETATM 11910 O O    . HOH E 3 .   ? -29.857 3.599   38.130 1.00 34.22 ?  410  HOH A O    1 
HETATM 11911 O O    . HOH E 3 .   ? -13.020 9.938   40.797 1.00 29.86 ?  411  HOH A O    1 
HETATM 11912 O O    . HOH E 3 .   ? -13.604 -9.089  20.495 1.00 23.44 ?  412  HOH A O    1 
HETATM 11913 O O    . HOH E 3 .   ? -2.124  2.853   33.306 1.00 24.29 ?  413  HOH A O    1 
HETATM 11914 O O    . HOH E 3 .   ? -21.920 -8.222  32.360 1.00 23.12 ?  414  HOH A O    1 
HETATM 11915 O O    . HOH E 3 .   ? -1.300  -13.573 25.717 1.00 34.13 ?  415  HOH A O    1 
HETATM 11916 O O    . HOH E 3 .   ? -23.693 23.513  18.973 1.00 24.88 ?  416  HOH A O    1 
HETATM 11917 O O    . HOH E 3 .   ? -3.982  16.186  49.637 1.00 44.04 ?  417  HOH A O    1 
HETATM 11918 O O    . HOH E 3 .   ? -28.695 34.470  17.448 1.00 37.64 ?  418  HOH A O    1 
HETATM 11919 O O    . HOH E 3 .   ? -27.467 9.311   12.393 1.00 18.71 ?  419  HOH A O    1 
HETATM 11920 O O    . HOH E 3 .   ? -9.780  7.423   41.508 1.00 21.35 ?  420  HOH A O    1 
HETATM 11921 O O    . HOH E 3 .   ? -12.326 5.334   43.424 1.00 23.49 ?  421  HOH A O    1 
HETATM 11922 O O    . HOH E 3 .   ? -10.540 37.878  10.452 1.00 36.23 ?  422  HOH A O    1 
HETATM 11923 O O    . HOH E 3 .   ? 10.338  21.659  26.173 1.00 25.67 ?  423  HOH A O    1 
HETATM 11924 O O    . HOH E 3 .   ? 8.712   16.851  30.047 1.00 23.51 ?  424  HOH A O    1 
HETATM 11925 O O    . HOH E 3 .   ? -23.760 10.194  45.895 1.00 33.17 ?  425  HOH A O    1 
HETATM 11926 O O    . HOH E 3 .   ? 8.102   -0.082  38.645 1.00 29.86 ?  426  HOH A O    1 
HETATM 11927 O O    . HOH E 3 .   ? -27.982 7.878   16.457 1.00 20.86 ?  427  HOH A O    1 
HETATM 11928 O O    . HOH E 3 .   ? -6.686  18.009  19.050 1.00 8.65  ?  428  HOH A O    1 
HETATM 11929 O O    . HOH E 3 .   ? -10.287 18.000  2.077  1.00 38.79 ?  429  HOH A O    1 
HETATM 11930 O O    . HOH E 3 .   ? -4.272  19.204  48.273 1.00 41.82 ?  430  HOH A O    1 
HETATM 11931 O O    . HOH E 3 .   ? -13.135 38.785  13.668 1.00 36.73 ?  431  HOH A O    1 
HETATM 11932 O O    . HOH E 3 .   ? -30.001 16.417  33.292 1.00 21.99 ?  432  HOH A O    1 
HETATM 11933 O O    . HOH E 3 .   ? -8.136  21.458  6.490  1.00 20.04 ?  433  HOH A O    1 
HETATM 11934 O O    . HOH E 3 .   ? -2.443  29.867  19.976 1.00 30.31 ?  434  HOH A O    1 
HETATM 11935 O O    . HOH E 3 .   ? -8.335  20.178  13.363 1.00 9.98  ?  435  HOH A O    1 
HETATM 11936 O O    . HOH E 3 .   ? -17.802 37.565  25.858 1.00 28.82 ?  436  HOH A O    1 
HETATM 11937 O O    . HOH E 3 .   ? -20.757 -10.290 22.608 1.00 30.41 ?  437  HOH A O    1 
HETATM 11938 O O    . HOH E 3 .   ? -30.592 13.031  24.361 1.00 21.80 ?  438  HOH A O    1 
HETATM 11939 O O    . HOH E 3 .   ? -5.307  -21.244 28.780 1.00 35.99 ?  439  HOH A O    1 
HETATM 11940 O O    . HOH E 3 .   ? 2.443   23.004  50.995 1.00 20.02 ?  440  HOH A O    1 
HETATM 11941 O O    . HOH E 3 .   ? 3.386   3.721   31.800 1.00 20.12 ?  441  HOH A O    1 
HETATM 11942 O O    . HOH E 3 .   ? -30.625 10.818  22.626 1.00 23.25 ?  442  HOH A O    1 
HETATM 11943 O O    . HOH E 3 .   ? 9.328   2.706   22.128 1.00 20.95 ?  443  HOH A O    1 
HETATM 11944 O O    . HOH E 3 .   ? -19.967 -2.976  16.222 1.00 31.93 ?  444  HOH A O    1 
HETATM 11945 O O    . HOH E 3 .   ? -5.478  -6.341  16.362 1.00 17.68 ?  445  HOH A O    1 
HETATM 11946 O O    . HOH E 3 .   ? 0.795   -6.765  33.693 1.00 14.34 ?  446  HOH A O    1 
HETATM 11947 O O    . HOH E 3 .   ? -21.963 -9.997  26.306 1.00 28.45 ?  447  HOH A O    1 
HETATM 11948 O O    . HOH E 3 .   ? -19.130 34.646  7.826  1.00 19.99 ?  448  HOH A O    1 
HETATM 11949 O O    . HOH E 3 .   ? -19.728 -10.944 35.000 1.00 28.68 ?  449  HOH A O    1 
HETATM 11950 O O    . HOH E 3 .   ? 3.628   20.389  8.329  1.00 26.83 ?  450  HOH A O    1 
HETATM 11951 O O    . HOH E 3 .   ? -28.075 39.890  22.901 1.00 39.61 ?  451  HOH A O    1 
HETATM 11952 O O    . HOH E 3 .   ? -16.966 19.151  4.954  1.00 13.57 ?  452  HOH A O    1 
HETATM 11953 O O    . HOH E 3 .   ? -20.812 -6.204  18.272 1.00 27.49 ?  453  HOH A O    1 
HETATM 11954 O O    . HOH E 3 .   ? 10.122  24.507  22.042 1.00 21.23 ?  454  HOH A O    1 
HETATM 11955 O O    . HOH E 3 .   ? 8.329   16.413  17.665 1.00 17.25 ?  455  HOH A O    1 
HETATM 11956 O O    . HOH E 3 .   ? -17.402 2.440   47.429 1.00 26.93 ?  456  HOH A O    1 
HETATM 11957 O O    . HOH E 3 .   ? 6.368   -10.492 32.963 1.00 35.70 ?  457  HOH A O    1 
HETATM 11958 O O    . HOH E 3 .   ? -14.085 3.322   44.279 1.00 22.95 ?  458  HOH A O    1 
HETATM 11959 O O    . HOH E 3 .   ? -30.117 33.082  18.980 1.00 29.52 ?  459  HOH A O    1 
HETATM 11960 O O    . HOH E 3 .   ? -10.099 14.904  3.721  1.00 30.92 ?  460  HOH A O    1 
HETATM 11961 O O    . HOH E 3 .   ? -26.911 0.874   18.351 1.00 36.48 ?  461  HOH A O    1 
HETATM 11962 O O    . HOH E 3 .   ? 3.424   21.480  33.494 1.00 12.01 ?  462  HOH A O    1 
HETATM 11963 O O    . HOH E 3 .   ? -0.742  11.210  33.884 1.00 9.03  ?  463  HOH A O    1 
HETATM 11964 O O    . HOH E 3 .   ? -22.124 -7.513  24.829 1.00 19.94 ?  464  HOH A O    1 
HETATM 11965 O O    . HOH E 3 .   ? -30.685 25.561  15.205 1.00 13.31 ?  465  HOH A O    1 
HETATM 11966 O O    . HOH E 3 .   ? -6.330  -12.063 44.462 1.00 22.78 ?  466  HOH A O    1 
HETATM 11967 O O    . HOH E 3 .   ? 7.441   -0.955  31.802 1.00 40.22 ?  467  HOH A O    1 
HETATM 11968 O O    . HOH E 3 .   ? 5.377   -11.576 25.958 1.00 41.14 ?  468  HOH A O    1 
HETATM 11969 O O    . HOH E 3 .   ? -15.871 -8.664  30.427 1.00 13.12 ?  469  HOH A O    1 
HETATM 11970 O O    . HOH E 3 .   ? -3.457  -20.607 35.134 1.00 30.02 ?  470  HOH A O    1 
HETATM 11971 O O    . HOH E 3 .   ? 0.150   5.001   34.729 1.00 18.71 ?  471  HOH A O    1 
HETATM 11972 O O    . HOH E 3 .   ? 18.728  12.652  21.735 1.00 36.65 ?  472  HOH A O    1 
HETATM 11973 O O    . HOH E 3 .   ? -11.567 24.826  18.910 1.00 7.42  ?  473  HOH A O    1 
HETATM 11974 O O    . HOH E 3 .   ? 0.470   -3.918  45.936 1.00 27.20 ?  474  HOH A O    1 
HETATM 11975 O O    . HOH E 3 .   ? -5.651  23.010  20.499 1.00 8.02  ?  475  HOH A O    1 
HETATM 11976 O O    . HOH E 3 .   ? 10.270  15.356  19.343 1.00 21.19 ?  476  HOH A O    1 
HETATM 11977 O O    . HOH E 3 .   ? -4.354  14.566  38.825 1.00 19.63 ?  477  HOH A O    1 
HETATM 11978 O O    . HOH E 3 .   ? -0.138  -7.985  44.515 1.00 21.78 ?  478  HOH A O    1 
HETATM 11979 O O    . HOH E 3 .   ? -14.342 0.947   4.630  1.00 24.74 ?  479  HOH A O    1 
HETATM 11980 O O    . HOH E 3 .   ? 2.134   -3.912  29.988 1.00 15.08 ?  480  HOH A O    1 
HETATM 11981 O O    . HOH E 3 .   ? -0.839  11.901  29.959 1.00 11.00 ?  481  HOH A O    1 
HETATM 11982 O O    . HOH E 3 .   ? -34.375 19.419  24.214 1.00 13.40 ?  482  HOH A O    1 
HETATM 11983 O O    . HOH E 3 .   ? -12.982 16.403  3.986  1.00 25.43 ?  483  HOH A O    1 
HETATM 11984 O O    . HOH E 3 .   ? 0.961   -11.418 22.292 1.00 32.54 ?  484  HOH A O    1 
HETATM 11985 O O    . HOH E 3 .   ? -21.774 10.313  35.585 1.00 12.30 ?  485  HOH A O    1 
HETATM 11986 O O    . HOH E 3 .   ? -10.657 -0.900  6.355  1.00 26.43 ?  486  HOH A O    1 
HETATM 11987 O O    . HOH E 3 .   ? -35.713 26.669  17.573 1.00 14.61 ?  487  HOH A O    1 
HETATM 11988 O O    . HOH E 3 .   ? -5.992  -5.890  13.358 1.00 23.46 ?  488  HOH A O    1 
HETATM 11989 O O    . HOH E 3 .   ? -17.933 13.346  4.926  1.00 18.36 ?  489  HOH A O    1 
HETATM 11990 O O    . HOH E 3 .   ? -0.770  5.762   10.369 1.00 25.13 ?  490  HOH A O    1 
HETATM 11991 O O    . HOH E 3 .   ? -33.691 19.772  29.129 1.00 21.45 ?  491  HOH A O    1 
HETATM 11992 O O    . HOH E 3 .   ? 13.046  13.197  28.587 1.00 16.10 ?  492  HOH A O    1 
HETATM 11993 O O    . HOH E 3 .   ? -1.053  -10.158 19.927 1.00 26.05 ?  493  HOH A O    1 
HETATM 11994 O O    . HOH E 3 .   ? 7.111   9.311   36.845 1.00 22.24 ?  494  HOH A O    1 
HETATM 11995 O O    . HOH E 3 .   ? -16.674 16.371  4.526  1.00 16.70 ?  495  HOH A O    1 
HETATM 11996 O O    . HOH E 3 .   ? 7.152   11.285  39.982 1.00 31.80 ?  496  HOH A O    1 
HETATM 11997 O O    . HOH E 3 .   ? 0.261   12.423  9.978  1.00 12.49 ?  497  HOH A O    1 
HETATM 11998 O O    . HOH E 3 .   ? -11.682 14.505  32.624 1.00 12.21 ?  498  HOH A O    1 
HETATM 11999 O O    . HOH E 3 .   ? -4.158  -4.862  14.833 1.00 32.17 ?  499  HOH A O    1 
HETATM 12000 O O    . HOH E 3 .   ? 12.187  10.634  18.316 1.00 23.97 ?  500  HOH A O    1 
HETATM 12001 O O    . HOH E 3 .   ? -4.981  15.686  4.596  1.00 18.75 ?  501  HOH A O    1 
HETATM 12002 O O    . HOH E 3 .   ? -1.311  25.783  27.615 1.00 17.38 ?  502  HOH A O    1 
HETATM 12003 O O    . HOH E 3 .   ? -27.865 31.538  28.379 1.00 18.35 ?  503  HOH A O    1 
HETATM 12004 O O    . HOH E 3 .   ? -11.709 32.819  33.061 1.00 14.48 ?  504  HOH A O    1 
HETATM 12005 O O    . HOH E 3 .   ? -23.777 16.747  9.007  1.00 15.73 ?  505  HOH A O    1 
HETATM 12006 O O    . HOH E 3 .   ? -0.654  -5.818  26.647 1.00 13.22 ?  506  HOH A O    1 
HETATM 12007 O O    . HOH E 3 .   ? -6.555  23.643  23.772 1.00 8.41  ?  507  HOH A O    1 
HETATM 12008 O O    . HOH E 3 .   ? -4.308  3.416   49.100 1.00 36.53 ?  508  HOH A O    1 
HETATM 12009 O O    . HOH E 3 .   ? -27.382 19.235  25.920 1.00 8.77  ?  509  HOH A O    1 
HETATM 12010 O O    . HOH E 3 .   ? -24.735 31.187  15.384 1.00 18.04 ?  510  HOH A O    1 
HETATM 12011 O O    . HOH E 3 .   ? -0.987  -0.698  18.196 1.00 11.07 ?  511  HOH A O    1 
HETATM 12012 O O    . HOH E 3 .   ? -17.145 8.479   47.746 1.00 41.53 ?  512  HOH A O    1 
HETATM 12013 O O    . HOH E 3 .   ? -20.434 0.583   14.916 1.00 24.19 ?  513  HOH A O    1 
HETATM 12014 O O    . HOH E 3 .   ? -26.464 30.164  17.725 1.00 13.32 ?  514  HOH A O    1 
HETATM 12015 O O    . HOH E 3 .   ? -17.387 3.554   13.546 1.00 20.27 ?  515  HOH A O    1 
HETATM 12016 O O    . HOH E 3 .   ? -15.640 -13.179 28.143 1.00 26.55 ?  516  HOH A O    1 
HETATM 12017 O O    . HOH E 3 .   ? -30.076 7.975   43.519 1.00 40.95 ?  517  HOH A O    1 
HETATM 12018 O O    . HOH E 3 .   ? -1.662  9.857   4.137  1.00 28.45 ?  518  HOH A O    1 
HETATM 12019 O O    . HOH E 3 .   ? -5.133  9.391   3.240  1.00 22.44 ?  519  HOH A O    1 
HETATM 12020 O O    . HOH E 3 .   ? -25.894 4.532   18.481 1.00 21.98 ?  520  HOH A O    1 
HETATM 12021 O O    . HOH E 3 .   ? 9.473   12.844  12.715 1.00 21.16 ?  521  HOH A O    1 
HETATM 12022 O O    . HOH E 3 .   ? -10.771 31.043  26.923 1.00 22.69 ?  522  HOH A O    1 
HETATM 12023 O O    . HOH E 3 .   ? 7.887   21.083  49.440 1.00 21.49 ?  523  HOH A O    1 
HETATM 12024 O O    . HOH E 3 .   ? -10.645 33.855  16.444 1.00 15.87 ?  524  HOH A O    1 
HETATM 12025 O O    . HOH E 3 .   ? 6.570   5.933   50.947 1.00 36.27 ?  525  HOH A O    1 
HETATM 12026 O O    . HOH E 3 .   ? -8.332  22.959  13.221 1.00 8.50  ?  526  HOH A O    1 
HETATM 12027 O O    . HOH E 3 .   ? -16.574 15.881  27.122 1.00 8.80  ?  527  HOH A O    1 
HETATM 12028 O O    . HOH E 3 .   ? -21.812 -2.519  21.160 1.00 29.55 ?  528  HOH A O    1 
HETATM 12029 O O    . HOH E 3 .   ? -11.983 22.392  20.103 1.00 8.48  ?  529  HOH A O    1 
HETATM 12030 O O    . HOH E 3 .   ? -20.754 29.993  22.204 1.00 10.07 ?  530  HOH A O    1 
HETATM 12031 O O    . HOH E 3 .   ? -12.540 7.706   35.560 1.00 10.98 ?  531  HOH A O    1 
HETATM 12032 O O    . HOH E 3 .   ? -18.663 -12.610 25.777 1.00 25.37 ?  532  HOH A O    1 
HETATM 12033 O O    . HOH E 3 .   ? 1.720   26.339  13.424 1.00 12.82 ?  533  HOH A O    1 
HETATM 12034 O O    . HOH E 3 .   ? 10.932  6.400   33.854 1.00 38.56 ?  534  HOH A O    1 
HETATM 12035 O O    . HOH E 3 .   ? -13.506 31.870  20.026 1.00 16.38 ?  535  HOH A O    1 
HETATM 12036 O O    . HOH E 3 .   ? -18.430 35.623  30.219 1.00 26.01 ?  536  HOH A O    1 
HETATM 12037 O O    . HOH E 3 .   ? -13.597 -7.541  22.631 1.00 12.44 ?  537  HOH A O    1 
HETATM 12038 O O    . HOH E 3 .   ? 11.075  19.663  15.786 1.00 25.09 ?  538  HOH A O    1 
HETATM 12039 O O    . HOH E 3 .   ? -32.271 6.736   27.417 1.00 36.65 ?  539  HOH A O    1 
HETATM 12040 O O    . HOH E 3 .   ? -7.429  19.672  10.709 1.00 11.04 ?  540  HOH A O    1 
HETATM 12041 O O    . HOH E 3 .   ? -6.798  7.237   43.163 1.00 26.45 ?  541  HOH A O    1 
HETATM 12042 O O    . HOH E 3 .   ? 1.040   17.353  45.479 1.00 31.49 ?  542  HOH A O    1 
HETATM 12043 O O    . HOH E 3 .   ? -24.211 20.462  4.834  1.00 15.75 ?  543  HOH A O    1 
HETATM 12044 O O    . HOH E 3 .   ? -28.742 27.647  13.397 1.00 12.67 ?  544  HOH A O    1 
HETATM 12045 O O    . HOH E 3 .   ? -24.968 1.467   19.959 1.00 27.00 ?  545  HOH A O    1 
HETATM 12046 O O    . HOH E 3 .   ? 8.664   15.287  14.427 1.00 22.65 ?  546  HOH A O    1 
HETATM 12047 O O    . HOH E 3 .   ? -18.319 12.168  43.181 1.00 28.25 ?  547  HOH A O    1 
HETATM 12048 O O    . HOH E 3 .   ? 1.706   28.880  20.044 1.00 28.22 ?  548  HOH A O    1 
HETATM 12049 O O    . HOH E 3 .   ? -20.799 26.827  31.328 1.00 14.49 ?  549  HOH A O    1 
HETATM 12050 O O    . HOH E 3 .   ? 6.512   -2.460  16.001 1.00 35.05 ?  550  HOH A O    1 
HETATM 12051 O O    . HOH E 3 .   ? 8.396   22.771  28.188 1.00 30.01 ?  551  HOH A O    1 
HETATM 12052 O O    . HOH E 3 .   ? -0.457  21.398  26.386 1.00 9.30  ?  552  HOH A O    1 
HETATM 12053 O O    . HOH E 3 .   ? -1.663  2.226   11.333 1.00 18.77 ?  553  HOH A O    1 
HETATM 12054 O O    . HOH E 3 .   ? -12.909 9.016   3.436  1.00 30.75 ?  554  HOH A O    1 
HETATM 12055 O O    . HOH E 3 .   ? 2.554   5.922   34.469 1.00 25.56 ?  555  HOH A O    1 
HETATM 12056 O O    . HOH E 3 .   ? -10.919 29.577  17.892 1.00 13.76 ?  556  HOH A O    1 
HETATM 12057 O O    . HOH E 3 .   ? -15.057 36.104  15.788 1.00 16.63 ?  557  HOH A O    1 
HETATM 12058 O O    . HOH E 3 .   ? -15.723 -15.909 43.432 1.00 34.17 ?  558  HOH A O    1 
HETATM 12059 O O    . HOH E 3 .   ? -8.991  -9.610  16.775 1.00 12.34 ?  559  HOH A O    1 
HETATM 12060 O O    . HOH E 3 .   ? -34.049 26.989  22.215 1.00 11.29 ?  560  HOH A O    1 
HETATM 12061 O O    . HOH E 3 .   ? 3.082   0.545   20.252 1.00 23.45 ?  561  HOH A O    1 
HETATM 12062 O O    . HOH E 3 .   ? 5.264   9.673   48.216 1.00 40.23 ?  562  HOH A O    1 
HETATM 12063 O O    . HOH E 3 .   ? 8.898   2.524   49.270 1.00 36.73 ?  563  HOH A O    1 
HETATM 12064 O O    . HOH E 3 .   ? 4.371   20.026  11.916 1.00 14.28 ?  564  HOH A O    1 
HETATM 12065 O O    . HOH E 3 .   ? -11.997 0.701   10.918 1.00 15.95 ?  565  HOH A O    1 
HETATM 12066 O O    . HOH E 3 .   ? 9.769   6.273   37.163 1.00 36.44 ?  566  HOH A O    1 
HETATM 12067 O O    . HOH E 3 .   ? -3.852  29.129  17.860 1.00 22.41 ?  567  HOH A O    1 
HETATM 12068 O O    . HOH E 3 .   ? -8.697  2.315   47.288 1.00 31.18 ?  568  HOH A O    1 
HETATM 12069 O O    . HOH E 3 .   ? -28.453 5.040   35.518 1.00 14.70 ?  569  HOH A O    1 
HETATM 12070 O O    . HOH E 3 .   ? 1.792   -6.919  26.487 1.00 29.69 ?  570  HOH A O    1 
HETATM 12071 O O    . HOH E 3 .   ? -21.348 -6.937  36.261 1.00 21.57 ?  571  HOH A O    1 
HETATM 12072 O O    . HOH E 3 .   ? -20.256 35.122  10.220 1.00 14.36 ?  572  HOH A O    1 
HETATM 12073 O O    . HOH E 3 .   ? -12.646 -4.311  24.675 1.00 9.55  ?  573  HOH A O    1 
HETATM 12074 O O    . HOH E 3 .   ? -16.706 3.629   10.905 1.00 18.68 ?  574  HOH A O    1 
HETATM 12075 O O    . HOH E 3 .   ? -14.396 34.836  24.664 1.00 23.24 ?  575  HOH A O    1 
HETATM 12076 O O    . HOH E 3 .   ? 11.965  13.221  18.716 1.00 24.26 ?  576  HOH A O    1 
HETATM 12077 O O    . HOH E 3 .   ? -25.930 20.339  7.047  1.00 16.62 ?  577  HOH A O    1 
HETATM 12078 O O    . HOH E 3 .   ? -19.598 12.154  37.875 1.00 26.83 ?  578  HOH A O    1 
HETATM 12079 O O    . HOH E 3 .   ? 0.060   -6.058  42.655 1.00 15.37 ?  579  HOH A O    1 
HETATM 12080 O O    . HOH E 3 .   ? -33.114 16.136  22.806 1.00 18.45 ?  580  HOH A O    1 
HETATM 12081 O O    . HOH E 3 .   ? -10.179 10.112  34.003 1.00 10.79 ?  581  HOH A O    1 
HETATM 12082 O O    . HOH E 3 .   ? 6.099   1.782   41.134 1.00 20.27 ?  582  HOH A O    1 
HETATM 12083 O O    . HOH E 3 .   ? -5.989  2.310   12.382 1.00 13.08 ?  583  HOH A O    1 
HETATM 12084 O O    . HOH E 3 .   ? -32.945 15.924  18.348 1.00 19.50 ?  584  HOH A O    1 
HETATM 12085 O O    . HOH E 3 .   ? -25.044 -0.002  33.068 1.00 14.91 ?  585  HOH A O    1 
HETATM 12086 O O    . HOH E 3 .   ? -29.927 11.276  26.457 1.00 29.83 ?  586  HOH A O    1 
HETATM 12087 O O    . HOH E 3 .   ? -4.165  16.913  18.831 1.00 8.51  ?  587  HOH A O    1 
HETATM 12088 O O    . HOH E 3 .   ? -9.969  -15.825 27.230 1.00 25.30 ?  588  HOH A O    1 
HETATM 12089 O O    . HOH E 3 .   ? -1.682  30.027  47.358 1.00 10.73 ?  589  HOH A O    1 
HETATM 12090 O O    . HOH E 3 .   ? -1.359  3.498   30.586 1.00 11.26 ?  590  HOH A O    1 
HETATM 12091 O O    . HOH E 3 .   ? -18.511 13.333  26.093 1.00 7.85  ?  591  HOH A O    1 
HETATM 12092 O O    . HOH E 3 .   ? -22.608 33.641  16.564 1.00 18.82 ?  592  HOH A O    1 
HETATM 12093 O O    . HOH E 3 .   ? -19.182 4.066   36.497 1.00 10.74 ?  593  HOH A O    1 
HETATM 12094 O O    . HOH E 3 .   ? -19.242 35.308  17.548 1.00 16.30 ?  594  HOH A O    1 
HETATM 12095 O O    . HOH E 3 .   ? -14.383 3.591   11.858 1.00 14.56 ?  595  HOH A O    1 
HETATM 12096 O O    . HOH E 3 .   ? -21.835 -4.774  37.691 1.00 17.47 ?  596  HOH A O    1 
HETATM 12097 O O    . HOH E 3 .   ? -11.444 5.981   6.267  1.00 12.53 ?  597  HOH A O    1 
HETATM 12098 O O    . HOH E 3 .   ? 10.864  20.406  23.793 1.00 31.94 ?  598  HOH A O    1 
HETATM 12099 O O    . HOH E 3 .   ? -0.844  -1.634  14.284 1.00 19.83 ?  599  HOH A O    1 
HETATM 12100 O O    . HOH E 3 .   ? -9.891  11.060  6.510  1.00 13.63 ?  600  HOH A O    1 
HETATM 12101 O O    . HOH E 3 .   ? -1.048  16.425  34.382 1.00 11.78 ?  601  HOH A O    1 
HETATM 12102 O O    . HOH E 3 .   ? -4.995  31.463  13.189 1.00 18.83 ?  602  HOH A O    1 
HETATM 12103 O O    . HOH E 3 .   ? 2.334   -13.038 37.017 1.00 19.89 ?  603  HOH A O    1 
HETATM 12104 O O    . HOH E 3 .   ? -28.997 31.538  14.328 1.00 22.53 ?  604  HOH A O    1 
HETATM 12105 O O    . HOH E 3 .   ? -19.152 10.791  4.958  1.00 16.83 ?  605  HOH A O    1 
HETATM 12106 O O    . HOH E 3 .   ? -10.849 -5.602  52.230 1.00 34.66 ?  606  HOH A O    1 
HETATM 12107 O O    . HOH E 3 .   ? -11.218 29.527  22.936 1.00 27.25 ?  607  HOH A O    1 
HETATM 12108 O O    . HOH E 3 .   ? -16.847 8.467   29.778 1.00 8.19  ?  608  HOH A O    1 
HETATM 12109 O O    . HOH E 3 .   ? 7.051   15.912  11.046 1.00 26.68 ?  609  HOH A O    1 
HETATM 12110 O O    . HOH E 3 .   ? -29.861 29.968  16.884 1.00 25.63 ?  610  HOH A O    1 
HETATM 12111 O O    . HOH E 3 .   ? 11.146  9.520   16.072 1.00 16.95 ?  611  HOH A O    1 
HETATM 12112 O O    . HOH E 3 .   ? 4.777   -0.607  41.232 1.00 18.19 ?  612  HOH A O    1 
HETATM 12113 O O    . HOH E 3 .   ? 0.078   26.952  49.520 1.00 12.34 ?  613  HOH A O    1 
HETATM 12114 O O    . HOH E 3 .   ? 5.997   15.305  34.731 1.00 17.87 ?  614  HOH A O    1 
HETATM 12115 O O    . HOH E 3 .   ? -4.325  4.730   9.431  1.00 14.27 ?  615  HOH A O    1 
HETATM 12116 O O    . HOH E 3 .   ? 0.087   20.869  43.897 1.00 38.16 ?  616  HOH A O    1 
HETATM 12117 O O    . HOH E 3 .   ? -30.602 20.422  13.676 1.00 12.61 ?  617  HOH A O    1 
HETATM 12118 O O    . HOH E 3 .   ? -22.855 6.440   8.385  1.00 18.54 ?  618  HOH A O    1 
HETATM 12119 O O    . HOH E 3 .   ? -8.307  8.767   6.305  1.00 13.75 ?  619  HOH A O    1 
HETATM 12120 O O    . HOH E 3 .   ? -33.020 27.707  16.210 1.00 15.89 ?  620  HOH A O    1 
HETATM 12121 O O    . HOH E 3 .   ? 6.472   21.832  51.772 1.00 17.60 ?  621  HOH A O    1 
HETATM 12122 O O    . HOH E 3 .   ? -6.571  9.005   43.549 1.00 38.59 ?  622  HOH A O    1 
HETATM 12123 O O    . HOH E 3 .   ? 13.710  11.493  32.278 1.00 35.17 ?  623  HOH A O    1 
HETATM 12124 O O    . HOH E 3 .   ? -12.255 -20.354 34.675 1.00 32.78 ?  624  HOH A O    1 
HETATM 12125 O O    . HOH E 3 .   ? -24.303 26.519  3.744  1.00 15.73 ?  625  HOH A O    1 
HETATM 12126 O O    . HOH E 3 .   ? 7.046   -2.142  13.635 1.00 41.48 ?  626  HOH A O    1 
HETATM 12127 O O    . HOH E 3 .   ? -6.479  3.021   9.763  1.00 14.06 ?  627  HOH A O    1 
HETATM 12128 O O    . HOH E 3 .   ? -27.996 1.563   40.629 1.00 31.70 ?  628  HOH A O    1 
HETATM 12129 O O    . HOH E 3 .   ? -16.262 33.742  5.152  1.00 25.93 ?  629  HOH A O    1 
HETATM 12130 O O    . HOH E 3 .   ? -18.008 -1.002  15.995 1.00 26.81 ?  630  HOH A O    1 
HETATM 12131 O O    . HOH E 3 .   ? 10.868  18.969  28.051 1.00 20.78 ?  631  HOH A O    1 
HETATM 12132 O O    . HOH E 3 .   ? 8.832   11.832  34.679 1.00 26.69 ?  632  HOH A O    1 
HETATM 12133 O O    . HOH E 3 .   ? -25.672 25.825  31.939 1.00 19.30 ?  633  HOH A O    1 
HETATM 12134 O O    . HOH E 3 .   ? 0.754   32.562  47.612 1.00 10.11 ?  634  HOH A O    1 
HETATM 12135 O O    . HOH E 3 .   ? -11.118 8.537   37.913 1.00 12.93 ?  635  HOH A O    1 
HETATM 12136 O O    . HOH E 3 .   ? -17.812 25.497  5.704  1.00 10.82 ?  636  HOH A O    1 
HETATM 12137 O O    . HOH E 3 .   ? 7.091   -7.066  31.179 1.00 27.47 ?  637  HOH A O    1 
HETATM 12138 O O    . HOH E 3 .   ? -9.518  27.992  8.849  1.00 13.04 ?  638  HOH A O    1 
HETATM 12139 O O    . HOH E 3 .   ? -11.005 -1.721  12.115 1.00 17.23 ?  639  HOH A O    1 
HETATM 12140 O O    . HOH E 3 .   ? -32.019 13.183  14.446 1.00 36.95 ?  640  HOH A O    1 
HETATM 12141 O O    . HOH E 3 .   ? -17.022 -16.780 35.276 1.00 28.32 ?  641  HOH A O    1 
HETATM 12142 O O    . HOH E 3 .   ? 11.138  15.842  46.650 1.00 37.74 ?  642  HOH A O    1 
HETATM 12143 O O    . HOH E 3 .   ? -1.061  16.763  38.602 1.00 17.25 ?  643  HOH A O    1 
HETATM 12144 O O    . HOH E 3 .   ? 9.552   -1.240  41.869 1.00 42.12 ?  644  HOH A O    1 
HETATM 12145 O O    . HOH E 3 .   ? 2.640   19.607  53.107 1.00 20.36 ?  645  HOH A O    1 
HETATM 12146 O O    . HOH E 3 .   ? -19.829 -14.868 35.770 1.00 37.20 ?  646  HOH A O    1 
HETATM 12147 O O    . HOH E 3 .   ? 2.676   13.685  10.453 1.00 11.36 ?  647  HOH A O    1 
HETATM 12148 O O    . HOH E 3 .   ? 2.616   -5.605  41.785 1.00 19.13 ?  648  HOH A O    1 
HETATM 12149 O O    . HOH E 3 .   ? -23.223 28.761  29.645 1.00 27.05 ?  649  HOH A O    1 
HETATM 12150 O O    . HOH E 3 .   ? -1.018  17.253  43.045 1.00 38.21 ?  650  HOH A O    1 
HETATM 12151 O O    . HOH E 3 .   ? 3.815   1.385   27.460 1.00 19.45 ?  651  HOH A O    1 
HETATM 12152 O O    . HOH E 3 .   ? -22.424 36.709  26.221 1.00 24.24 ?  652  HOH A O    1 
HETATM 12153 O O    . HOH E 3 .   ? -25.986 -0.243  40.958 1.00 22.34 ?  653  HOH A O    1 
HETATM 12154 O O    . HOH E 3 .   ? 1.094   3.904   10.452 1.00 35.94 ?  654  HOH A O    1 
HETATM 12155 O O    . HOH E 3 .   ? -28.055 17.215  8.989  1.00 24.90 ?  655  HOH A O    1 
HETATM 12156 O O    . HOH E 3 .   ? -17.498 36.531  28.232 1.00 29.03 ?  656  HOH A O    1 
HETATM 12157 O O    . HOH E 3 .   ? 12.389  17.624  21.648 1.00 32.11 ?  657  HOH A O    1 
HETATM 12158 O O    . HOH E 3 .   ? -29.119 2.846   33.028 1.00 18.79 ?  658  HOH A O    1 
HETATM 12159 O O    . HOH E 3 .   ? -32.021 30.471  25.564 1.00 17.82 ?  659  HOH A O    1 
HETATM 12160 O O    . HOH E 3 .   ? 5.255   26.087  27.099 1.00 14.44 ?  660  HOH A O    1 
HETATM 12161 O O    . HOH E 3 .   ? -1.986  28.804  16.383 1.00 27.15 ?  661  HOH A O    1 
HETATM 12162 O O    . HOH E 3 .   ? 1.154   -2.375  48.104 1.00 25.77 ?  662  HOH A O    1 
HETATM 12163 O O    . HOH E 3 .   ? -20.978 -10.318 48.776 1.00 34.21 ?  663  HOH A O    1 
HETATM 12164 O O    . HOH E 3 .   ? -9.873  -14.309 42.546 1.00 26.79 ?  664  HOH A O    1 
HETATM 12165 O O    . HOH E 3 .   ? -17.550 6.348   32.430 1.00 10.46 ?  665  HOH A O    1 
HETATM 12166 O O    . HOH E 3 .   ? 1.022   5.804   6.642  1.00 33.44 ?  666  HOH A O    1 
HETATM 12167 O O    . HOH E 3 .   ? -2.131  -7.588  18.050 1.00 18.94 ?  667  HOH A O    1 
HETATM 12168 O O    . HOH E 3 .   ? -28.483 2.410   11.980 1.00 29.23 ?  668  HOH A O    1 
HETATM 12169 O O    . HOH E 3 .   ? -8.516  27.165  18.588 1.00 9.00  ?  669  HOH A O    1 
HETATM 12170 O O    . HOH E 3 .   ? -6.743  2.925   6.128  1.00 28.91 ?  670  HOH A O    1 
HETATM 12171 O O    . HOH E 3 .   ? -19.635 30.923  32.126 1.00 16.36 ?  671  HOH A O    1 
HETATM 12172 O O    . HOH E 3 .   ? -23.627 33.927  28.364 1.00 24.61 ?  672  HOH A O    1 
HETATM 12173 O O    . HOH E 3 .   ? -18.463 -11.882 23.479 1.00 22.80 ?  673  HOH A O    1 
HETATM 12174 O O    . HOH E 3 .   ? 9.595   0.168   18.432 1.00 36.91 ?  674  HOH A O    1 
HETATM 12175 O O    . HOH E 3 .   ? 3.805   -10.402 43.057 1.00 33.89 ?  675  HOH A O    1 
HETATM 12176 O O    . HOH E 3 .   ? 4.047   21.552  28.975 1.00 9.67  ?  676  HOH A O    1 
HETATM 12177 O O    . HOH E 3 .   ? -30.714 7.266   25.961 1.00 35.60 ?  677  HOH A O    1 
HETATM 12178 O O    . HOH E 3 .   ? 2.462   3.391   52.420 1.00 33.45 ?  678  HOH A O    1 
HETATM 12179 O O    . HOH E 3 .   ? -3.801  25.453  26.538 1.00 13.65 ?  679  HOH A O    1 
HETATM 12180 O O    . HOH E 3 .   ? 11.585  6.215   27.002 1.00 20.03 ?  680  HOH A O    1 
HETATM 12181 O O    . HOH E 3 .   ? 18.093  10.522  21.989 1.00 41.34 ?  681  HOH A O    1 
HETATM 12182 O O    . HOH E 3 .   ? 7.870   18.639  34.235 1.00 28.28 ?  682  HOH A O    1 
HETATM 12183 O O    . HOH E 3 .   ? -16.130 19.626  31.181 1.00 8.57  ?  683  HOH A O    1 
HETATM 12184 O O    . HOH E 3 .   ? 6.307   24.127  42.661 1.00 18.62 ?  684  HOH A O    1 
HETATM 12185 O O    . HOH E 3 .   ? -3.874  -4.345  47.142 1.00 23.03 ?  685  HOH A O    1 
HETATM 12186 O O    . HOH E 3 .   ? -16.890 -17.261 32.100 1.00 29.47 ?  686  HOH A O    1 
HETATM 12187 O O    . HOH E 3 .   ? -29.664 13.668  12.247 1.00 19.33 ?  687  HOH A O    1 
HETATM 12188 O O    . HOH E 3 .   ? 7.954   4.018   10.475 1.00 35.20 ?  688  HOH A O    1 
HETATM 12189 O O    . HOH E 3 .   ? -12.012 -10.884 24.482 1.00 16.30 ?  689  HOH A O    1 
HETATM 12190 O O    . HOH E 3 .   ? 9.991   26.430  18.345 1.00 21.02 ?  690  HOH A O    1 
HETATM 12191 O O    . HOH E 3 .   ? 1.436   30.527  17.784 1.00 35.54 ?  691  HOH A O    1 
HETATM 12192 O O    . HOH E 3 .   ? -25.120 6.386   9.747  1.00 32.36 ?  692  HOH A O    1 
HETATM 12193 O O    . HOH E 3 .   ? 3.096   5.977   9.468  1.00 32.21 ?  693  HOH A O    1 
HETATM 12194 O O    . HOH E 3 .   ? -15.640 -1.419  15.628 1.00 16.35 ?  694  HOH A O    1 
HETATM 12195 O O    . HOH E 3 .   ? -24.309 15.621  6.532  1.00 21.81 ?  695  HOH A O    1 
HETATM 12196 O O    . HOH E 3 .   ? -17.914 -3.756  8.832  1.00 38.15 ?  696  HOH A O    1 
HETATM 12197 O O    . HOH E 3 .   ? -6.316  29.981  20.357 1.00 13.33 ?  697  HOH A O    1 
HETATM 12198 O O    . HOH E 3 .   ? -13.439 -15.781 39.531 1.00 23.00 ?  698  HOH A O    1 
HETATM 12199 O O    . HOH E 3 .   ? -4.325  32.155  15.909 1.00 22.90 ?  699  HOH A O    1 
HETATM 12200 O O    . HOH E 3 .   ? -25.386 -4.673  42.897 1.00 29.04 ?  700  HOH A O    1 
HETATM 12201 O O    . HOH E 3 .   ? 2.517   26.441  41.749 1.00 14.55 ?  701  HOH A O    1 
HETATM 12202 O O    . HOH E 3 .   ? -24.336 0.958   48.290 1.00 30.63 ?  702  HOH A O    1 
HETATM 12203 O O    . HOH E 3 .   ? 5.348   -1.329  46.263 1.00 34.25 ?  703  HOH A O    1 
HETATM 12204 O O    . HOH E 3 .   ? -29.336 14.028  36.109 1.00 24.67 ?  704  HOH A O    1 
HETATM 12205 O O    . HOH E 3 .   ? 6.523   29.728  22.061 1.00 28.66 ?  705  HOH A O    1 
HETATM 12206 O O    . HOH E 3 .   ? -12.367 11.016  35.520 1.00 11.40 ?  706  HOH A O    1 
HETATM 12207 O O    . HOH E 3 .   ? -12.209 22.577  7.498  1.00 10.98 ?  707  HOH A O    1 
HETATM 12208 O O    . HOH E 3 .   ? -29.617 -0.681  30.724 1.00 40.82 ?  708  HOH A O    1 
HETATM 12209 O O    . HOH E 3 .   ? -27.485 19.222  22.347 1.00 18.29 ?  709  HOH A O    1 
HETATM 12210 O O    . HOH E 3 .   ? -29.093 2.042   20.204 1.00 27.50 ?  710  HOH A O    1 
HETATM 12211 O O    . HOH E 3 .   ? 2.321   25.215  48.930 1.00 24.52 ?  711  HOH A O    1 
HETATM 12212 O O    . HOH E 3 .   ? 4.499   18.376  38.735 1.00 29.26 ?  712  HOH A O    1 
HETATM 12213 O O    . HOH E 3 .   ? -36.236 21.850  17.426 1.00 22.16 ?  713  HOH A O    1 
HETATM 12214 O O    . HOH E 3 .   ? -22.711 37.867  23.198 1.00 25.90 ?  714  HOH A O    1 
HETATM 12215 O O    . HOH E 3 .   ? 1.478   20.631  40.409 1.00 30.25 ?  715  HOH A O    1 
HETATM 12216 O O    . HOH E 3 .   ? -15.564 -2.626  13.194 1.00 24.66 ?  716  HOH A O    1 
HETATM 12217 O O    . HOH E 3 .   ? 11.951  6.372   29.695 1.00 32.77 ?  717  HOH A O    1 
HETATM 12218 O O    . HOH E 3 .   ? 14.102  5.952   25.565 1.00 25.07 ?  718  HOH A O    1 
HETATM 12219 O O    . HOH E 3 .   ? -13.573 -13.877 29.760 1.00 18.00 ?  719  HOH A O    1 
HETATM 12220 O O    . HOH E 3 .   ? -12.175 -8.564  11.351 1.00 23.39 ?  720  HOH A O    1 
HETATM 12221 O O    . HOH E 3 .   ? -1.799  14.820  42.065 1.00 21.90 ?  721  HOH A O    1 
HETATM 12222 O O    . HOH E 3 .   ? -15.236 38.771  10.552 1.00 32.65 ?  722  HOH A O    1 
HETATM 12223 O O    . HOH E 3 .   ? -31.964 28.342  28.772 1.00 25.71 ?  723  HOH A O    1 
HETATM 12224 O O    . HOH E 3 .   ? -31.007 5.586   33.432 1.00 16.87 ?  724  HOH A O    1 
HETATM 12225 O O    . HOH E 3 .   ? -18.720 -9.996  32.522 1.00 22.77 ?  725  HOH A O    1 
HETATM 12226 O O    . HOH E 3 .   ? 0.426   -14.814 28.089 1.00 29.94 ?  726  HOH A O    1 
HETATM 12227 O O    . HOH E 3 .   ? -15.181 -12.996 25.970 1.00 25.43 ?  727  HOH A O    1 
HETATM 12228 O O    . HOH E 3 .   ? 7.212   21.736  41.909 1.00 21.74 ?  728  HOH A O    1 
HETATM 12229 O O    . HOH E 3 .   ? 1.445   -13.678 30.405 1.00 25.16 ?  729  HOH A O    1 
HETATM 12230 O O    . HOH E 3 .   ? -13.237 2.409   1.408  1.00 40.27 ?  730  HOH A O    1 
HETATM 12231 O O    . HOH E 3 .   ? -11.037 20.035  19.109 1.00 7.37  ?  731  HOH A O    1 
HETATM 12232 O O    . HOH E 3 .   ? 6.919   1.887   28.390 1.00 30.12 ?  732  HOH A O    1 
HETATM 12233 O O    . HOH E 3 .   ? -15.832 -9.938  32.959 1.00 13.22 ?  733  HOH A O    1 
HETATM 12234 O O    . HOH E 3 .   ? -14.846 7.312   46.578 1.00 36.25 ?  734  HOH A O    1 
HETATM 12235 O O    . HOH E 3 .   ? -25.664 -9.079  41.099 1.00 40.21 ?  735  HOH A O    1 
HETATM 12236 O O    . HOH E 3 .   ? 11.322  14.426  30.199 1.00 22.35 ?  736  HOH A O    1 
HETATM 12237 O O    . HOH E 3 .   ? -2.683  -7.104  45.766 1.00 23.21 ?  737  HOH A O    1 
HETATM 12238 O O    . HOH E 3 .   ? -23.852 -1.111  21.966 1.00 26.35 ?  738  HOH A O    1 
HETATM 12239 O O    . HOH E 3 .   ? 6.483   -0.799  43.589 1.00 32.57 ?  739  HOH A O    1 
HETATM 12240 O O    . HOH E 3 .   ? -6.461  -16.615 44.449 1.00 36.91 ?  740  HOH A O    1 
HETATM 12241 O O    . HOH E 3 .   ? -5.012  0.313   9.620  1.00 20.71 ?  741  HOH A O    1 
HETATM 12242 O O    . HOH E 3 .   ? -24.961 -10.079 43.235 1.00 32.83 ?  742  HOH A O    1 
HETATM 12243 O O    . HOH E 3 .   ? -21.390 12.370  33.802 1.00 11.23 ?  743  HOH A O    1 
HETATM 12244 O O    . HOH E 3 .   ? 7.521   10.389  9.054  1.00 32.88 ?  744  HOH A O    1 
HETATM 12245 O O    . HOH E 3 .   ? -7.227  0.178   48.398 1.00 36.51 ?  745  HOH A O    1 
HETATM 12246 O O    . HOH E 3 .   ? -15.933 -10.592 23.296 1.00 28.21 ?  746  HOH A O    1 
HETATM 12247 O O    . HOH E 3 .   ? -8.236  22.298  10.528 1.00 10.45 ?  747  HOH A O    1 
HETATM 12248 O O    . HOH E 3 .   ? -20.549 6.366   48.471 1.00 25.81 ?  748  HOH A O    1 
HETATM 12249 O O    . HOH E 3 .   ? -10.831 38.075  15.603 1.00 34.90 ?  749  HOH A O    1 
HETATM 12250 O O    . HOH E 3 .   ? -21.141 -7.160  48.890 1.00 27.38 ?  750  HOH A O    1 
HETATM 12251 O O    . HOH E 3 .   ? -17.638 -12.538 43.549 1.00 24.34 ?  751  HOH A O    1 
HETATM 12252 O O    . HOH E 3 .   ? -15.867 -4.278  7.079  1.00 37.48 ?  752  HOH A O    1 
HETATM 12253 O O    . HOH E 3 .   ? -21.627 -13.114 38.161 1.00 24.22 ?  753  HOH A O    1 
HETATM 12254 O O    . HOH E 3 .   ? -33.642 7.924   35.050 1.00 38.63 ?  754  HOH A O    1 
HETATM 12255 O O    . HOH E 3 .   ? -2.688  22.420  32.511 1.00 21.06 ?  755  HOH A O    1 
HETATM 12256 O O    . HOH E 3 .   ? -25.334 -0.456  30.240 1.00 20.00 ?  756  HOH A O    1 
HETATM 12257 O O    . HOH E 3 .   ? -27.990 5.688   47.158 1.00 35.80 ?  757  HOH A O    1 
HETATM 12258 O O    . HOH E 3 .   ? -10.075 28.139  25.244 1.00 17.61 ?  758  HOH A O    1 
HETATM 12259 O O    . HOH E 3 .   ? -25.608 14.658  40.756 1.00 22.13 ?  759  HOH A O    1 
HETATM 12260 O O    . HOH E 3 .   ? -22.053 18.072  2.339  1.00 24.13 ?  760  HOH A O    1 
HETATM 12261 O O    . HOH E 3 .   ? 5.238   -2.906  19.482 1.00 38.60 ?  761  HOH A O    1 
HETATM 12262 O O    . HOH E 3 .   ? -19.578 6.055   34.444 1.00 11.60 ?  762  HOH A O    1 
HETATM 12263 O O    . HOH E 3 .   ? -4.478  -2.186  12.166 1.00 19.91 ?  763  HOH A O    1 
HETATM 12264 O O    . HOH E 3 .   ? -20.142 -8.370  14.145 1.00 18.37 ?  764  HOH A O    1 
HETATM 12265 O O    . HOH E 3 .   ? 5.520   11.161  7.533  1.00 24.10 ?  765  HOH A O    1 
HETATM 12266 O O    . HOH E 3 .   ? 6.682   8.890   10.433 1.00 25.16 ?  766  HOH A O    1 
HETATM 12267 O O    . HOH E 3 .   ? 6.549   16.661  19.787 1.00 11.29 ?  767  HOH A O    1 
HETATM 12268 O O    . HOH E 3 .   ? -10.422 5.711   3.549  1.00 27.26 ?  768  HOH A O    1 
HETATM 12269 O O    . HOH E 3 .   ? -18.959 -5.779  49.941 1.00 30.29 ?  769  HOH A O    1 
HETATM 12270 O O    . HOH E 3 .   ? -23.810 8.666   19.507 1.00 18.69 ?  770  HOH A O    1 
HETATM 12271 O O    . HOH E 3 .   ? -20.202 2.946   48.215 1.00 22.00 ?  771  HOH A O    1 
HETATM 12272 O O    . HOH E 3 .   ? -30.624 29.502  21.243 1.00 19.23 ?  772  HOH A O    1 
HETATM 12273 O O    . HOH E 3 .   ? 7.374   12.877  41.794 1.00 39.06 ?  773  HOH A O    1 
HETATM 12274 O O    . HOH E 3 .   ? -15.965 35.091  22.668 1.00 21.89 ?  774  HOH A O    1 
HETATM 12275 O O    . HOH E 3 .   ? 1.538   29.162  14.353 1.00 25.36 ?  775  HOH A O    1 
HETATM 12276 O O    . HOH E 3 .   ? -23.522 0.045   10.492 1.00 29.00 ?  776  HOH A O    1 
HETATM 12277 O O    . HOH E 3 .   ? -5.697  12.079  38.395 1.00 14.19 ?  777  HOH A O    1 
HETATM 12278 O O    . HOH E 3 .   ? -25.241 12.692  7.708  1.00 25.52 ?  778  HOH A O    1 
HETATM 12279 O O    . HOH E 3 .   ? -6.155  16.217  32.524 1.00 14.02 ?  779  HOH A O    1 
HETATM 12280 O O    . HOH E 3 .   ? 5.637   -12.053 35.835 1.00 25.69 ?  780  HOH A O    1 
HETATM 12281 O O    . HOH E 3 .   ? -9.554  -5.424  5.315  1.00 41.97 ?  781  HOH A O    1 
HETATM 12282 O O    . HOH E 3 .   ? 2.022   15.100  44.493 1.00 33.12 ?  782  HOH A O    1 
HETATM 12283 O O    . HOH E 3 .   ? 15.334  15.090  22.752 1.00 19.75 ?  783  HOH A O    1 
HETATM 12284 O O    . HOH E 3 .   ? -31.325 16.380  31.069 1.00 20.02 ?  784  HOH A O    1 
HETATM 12285 O O    . HOH E 3 .   ? -33.611 14.244  11.235 1.00 42.18 ?  785  HOH A O    1 
HETATM 12286 O O    . HOH E 3 .   ? -6.696  -5.775  49.836 1.00 37.23 ?  786  HOH A O    1 
HETATM 12287 O O    . HOH E 3 .   ? -2.002  28.221  25.517 1.00 25.15 ?  787  HOH A O    1 
HETATM 12288 O O    . HOH E 3 .   ? -18.860 8.491   14.308 1.00 24.41 ?  788  HOH A O    1 
HETATM 12289 O O    . HOH E 3 .   ? -13.252 -15.686 36.629 1.00 22.97 ?  789  HOH A O    1 
HETATM 12290 O O    . HOH E 3 .   ? -19.223 -9.101  36.816 1.00 21.17 ?  790  HOH A O    1 
HETATM 12291 O O    . HOH E 3 .   ? 3.757   21.964  41.310 1.00 24.14 ?  791  HOH A O    1 
HETATM 12292 O O    . HOH E 3 .   ? -2.588  -15.820 26.371 1.00 32.37 ?  792  HOH A O    1 
HETATM 12293 O O    . HOH E 3 .   ? -3.579  30.893  9.577  1.00 42.29 ?  793  HOH A O    1 
HETATM 12294 O O    . HOH E 3 .   ? 0.310   -2.415  26.752 1.00 14.96 ?  794  HOH A O    1 
HETATM 12295 O O    . HOH E 3 .   ? -24.703 12.594  44.381 1.00 24.55 ?  795  HOH A O    1 
HETATM 12296 O O    . HOH E 3 .   ? -3.834  18.052  32.324 1.00 21.57 ?  796  HOH A O    1 
HETATM 12297 O O    . HOH E 3 .   ? -16.249 10.434  44.319 1.00 31.86 ?  797  HOH A O    1 
HETATM 12298 O O    . HOH E 3 .   ? -6.451  33.380  18.716 1.00 35.21 ?  798  HOH A O    1 
HETATM 12299 O O    . HOH E 3 .   ? 9.464   3.087   35.186 1.00 23.07 ?  799  HOH A O    1 
HETATM 12300 O O    . HOH E 3 .   ? -5.806  7.521   7.074  1.00 12.03 ?  800  HOH A O    1 
HETATM 12301 O O    . HOH E 3 .   ? -10.535 29.079  20.669 1.00 19.16 ?  801  HOH A O    1 
HETATM 12302 O O    . HOH E 3 .   ? -36.451 26.506  23.332 1.00 14.83 ?  802  HOH A O    1 
HETATM 12303 O O    . HOH E 3 .   ? -14.372 26.196  31.376 1.00 17.06 ?  803  HOH A O    1 
HETATM 12304 O O    . HOH E 3 .   ? 9.604   6.868   43.060 1.00 32.74 ?  804  HOH A O    1 
HETATM 12305 O O    . HOH E 3 .   ? -22.758 31.564  29.195 1.00 18.31 ?  805  HOH A O    1 
HETATM 12306 O O    . HOH E 3 .   ? -2.861  -12.338 23.787 1.00 15.76 ?  806  HOH A O    1 
HETATM 12307 O O    . HOH E 3 .   ? -35.896 22.739  14.468 1.00 30.02 ?  807  HOH A O    1 
HETATM 12308 O O    . HOH E 3 .   ? 6.022   1.942   51.403 1.00 32.74 ?  808  HOH A O    1 
HETATM 12309 O O    . HOH E 3 .   ? 2.583   -0.921  26.581 1.00 23.33 ?  809  HOH A O    1 
HETATM 12310 O O    . HOH E 3 .   ? -14.952 0.717   11.368 1.00 29.13 ?  810  HOH A O    1 
HETATM 12311 O O    . HOH E 3 .   ? 1.071   -11.469 43.987 1.00 23.26 ?  811  HOH A O    1 
HETATM 12312 O O    . HOH E 3 .   ? -27.339 13.006  7.817  1.00 37.04 ?  812  HOH A O    1 
HETATM 12313 O O    . HOH E 3 .   ? 8.480   0.715   13.275 1.00 28.70 ?  813  HOH A O    1 
HETATM 12314 O O    . HOH E 3 .   ? -14.161 29.290  36.086 1.00 20.54 ?  814  HOH A O    1 
HETATM 12315 O O    . HOH E 3 .   ? 15.688  12.429  25.282 1.00 17.28 ?  815  HOH A O    1 
HETATM 12316 O O    . HOH E 3 .   ? -6.495  -2.346  47.548 1.00 24.96 ?  816  HOH A O    1 
HETATM 12317 O O    . HOH E 3 .   ? 4.709   21.005  36.725 1.00 27.92 ?  817  HOH A O    1 
HETATM 12318 O O    . HOH E 3 .   ? -30.160 17.928  34.926 1.00 32.78 ?  818  HOH A O    1 
HETATM 12319 O O    . HOH E 3 .   ? -28.982 -0.205  22.011 1.00 36.85 ?  819  HOH A O    1 
HETATM 12320 O O    . HOH E 3 .   ? -7.805  11.221  41.452 1.00 32.70 ?  820  HOH A O    1 
HETATM 12321 O O    . HOH E 3 .   ? -33.568 12.696  22.204 1.00 31.02 ?  821  HOH A O    1 
HETATM 12322 O O    . HOH E 3 .   ? -1.222  28.198  19.280 1.00 25.23 ?  822  HOH A O    1 
HETATM 12323 O O    . HOH E 3 .   ? -25.895 35.435  29.099 1.00 34.74 ?  823  HOH A O    1 
HETATM 12324 O O    . HOH E 3 .   ? 9.010   9.983   41.376 1.00 38.04 ?  824  HOH A O    1 
HETATM 12325 O O    . HOH E 3 .   ? -1.908  -4.674  24.275 1.00 14.32 ?  825  HOH A O    1 
HETATM 12326 O O    . HOH E 3 .   ? 13.665  5.103   14.449 1.00 46.39 ?  826  HOH A O    1 
HETATM 12327 O O    . HOH E 3 .   ? -21.230 24.336  31.503 1.00 17.27 ?  827  HOH A O    1 
HETATM 12328 O O    . HOH E 3 .   ? 2.223   8.700   32.155 1.00 18.77 ?  828  HOH A O    1 
HETATM 12329 O O    . HOH E 3 .   ? -8.372  27.492  25.584 1.00 25.80 ?  829  HOH A O    1 
HETATM 12330 O O    . HOH E 3 .   ? 8.139   0.663   20.748 1.00 22.36 ?  830  HOH A O    1 
HETATM 12331 O O    . HOH E 3 .   ? 10.582  19.557  41.719 1.00 34.75 ?  831  HOH A O    1 
HETATM 12332 O O    . HOH E 3 .   ? -13.965 -7.954  52.272 1.00 38.61 ?  832  HOH A O    1 
HETATM 12333 O O    . HOH E 3 .   ? -0.285  29.569  22.496 1.00 31.08 ?  833  HOH A O    1 
HETATM 12334 O O    . HOH E 3 .   ? 3.182   -18.661 36.204 1.00 43.63 ?  834  HOH A O    1 
HETATM 12335 O O    . HOH E 3 .   ? -13.602 12.863  3.224  1.00 38.10 ?  835  HOH A O    1 
HETATM 12336 O O    . HOH E 3 .   ? -3.251  18.759  42.869 1.00 43.78 ?  836  HOH A O    1 
HETATM 12337 O O    . HOH E 3 .   ? 6.004   -1.897  24.068 1.00 35.61 ?  837  HOH A O    1 
HETATM 12338 O O    . HOH E 3 .   ? -40.019 21.592  22.563 1.00 29.49 ?  838  HOH A O    1 
HETATM 12339 O O    . HOH E 3 .   ? -2.782  6.726   7.915  1.00 14.16 ?  839  HOH A O    1 
HETATM 12340 O O    . HOH E 3 .   ? -1.460  20.624  46.143 1.00 39.30 ?  840  HOH A O    1 
HETATM 12341 O O    . HOH E 3 .   ? 3.726   -3.428  43.118 1.00 32.18 ?  841  HOH A O    1 
HETATM 12342 O O    . HOH E 3 .   ? -2.007  28.601  8.500  1.00 30.12 ?  842  HOH A O    1 
HETATM 12343 O O    . HOH E 3 .   ? -32.086 33.309  26.147 1.00 28.83 ?  843  HOH A O    1 
HETATM 12344 O O    . HOH E 3 .   ? 10.274  0.405   34.278 1.00 42.87 ?  844  HOH A O    1 
HETATM 12345 O O    . HOH E 3 .   ? 2.615   30.627  25.020 1.00 37.38 ?  845  HOH A O    1 
HETATM 12346 O O    . HOH E 3 .   ? -31.870 4.789   24.927 1.00 41.72 ?  846  HOH A O    1 
HETATM 12347 O O    . HOH E 3 .   ? 4.468   -11.740 30.072 1.00 33.94 ?  847  HOH A O    1 
HETATM 12348 O O    . HOH E 3 .   ? -2.341  18.741  35.087 1.00 19.78 ?  848  HOH A O    1 
HETATM 12349 O O    . HOH E 3 .   ? -17.157 6.574   2.335  1.00 38.24 ?  849  HOH A O    1 
HETATM 12350 O O    . HOH E 3 .   ? -19.242 2.590   7.867  1.00 30.57 ?  850  HOH A O    1 
HETATM 12351 O O    . HOH E 3 .   ? -26.312 28.645  31.731 1.00 27.38 ?  851  HOH A O    1 
HETATM 12352 O O    . HOH E 3 .   ? -19.605 13.821  40.216 1.00 35.30 ?  852  HOH A O    1 
HETATM 12353 O O    . HOH E 3 .   ? 5.753   16.767  37.208 1.00 31.87 ?  853  HOH A O    1 
HETATM 12354 O O    . HOH E 3 .   ? -21.991 1.112   49.620 1.00 35.15 ?  854  HOH A O    1 
HETATM 12355 O O    . HOH E 3 .   ? -34.735 15.474  14.490 1.00 38.42 ?  855  HOH A O    1 
HETATM 12356 O O    . HOH E 3 .   ? 0.668   22.816  48.020 1.00 25.27 ?  856  HOH A O    1 
HETATM 12357 O O    . HOH E 3 .   ? -8.018  34.829  16.724 1.00 28.57 ?  857  HOH A O    1 
HETATM 12358 O O    . HOH E 3 .   ? -12.374 35.944  16.781 1.00 20.53 ?  858  HOH A O    1 
HETATM 12359 O O    . HOH E 3 .   ? 4.082   -2.423  29.012 1.00 28.88 ?  859  HOH A O    1 
HETATM 12360 O O    . HOH E 3 .   ? -14.501 11.257  42.901 1.00 40.35 ?  860  HOH A O    1 
HETATM 12361 O O    . HOH E 3 .   ? -5.397  29.367  23.716 1.00 27.73 ?  861  HOH A O    1 
HETATM 12362 O O    . HOH E 3 .   ? -31.280 30.144  30.871 1.00 40.46 ?  862  HOH A O    1 
HETATM 12363 O O    . HOH E 3 .   ? -15.579 13.031  2.760  1.00 41.44 ?  863  HOH A O    1 
HETATM 12364 O O    . HOH E 3 .   ? -12.597 -16.422 29.154 1.00 20.32 ?  864  HOH A O    1 
HETATM 12365 O O    . HOH E 3 .   ? 0.548   -7.525  20.425 1.00 30.09 ?  865  HOH A O    1 
HETATM 12366 O O    . HOH E 3 .   ? 5.287   17.485  10.949 1.00 20.32 ?  866  HOH A O    1 
HETATM 12367 O O    . HOH E 3 .   ? -6.385  2.337   47.741 1.00 36.38 ?  867  HOH A O    1 
HETATM 12368 O O    . HOH E 3 .   ? -20.850 37.587  17.731 1.00 27.87 ?  868  HOH A O    1 
HETATM 12369 O O    . HOH E 3 .   ? 0.218   22.637  41.738 1.00 36.71 ?  869  HOH A O    1 
HETATM 12370 O O    . HOH E 3 .   ? -30.408 2.162   35.521 1.00 38.93 ?  870  HOH A O    1 
HETATM 12371 O O    . HOH E 3 .   ? -22.257 24.569  4.217  1.00 11.53 ?  871  HOH A O    1 
HETATM 12372 O O    . HOH E 3 .   ? -15.019 38.443  14.786 1.00 32.70 ?  872  HOH A O    1 
HETATM 12373 O O    . HOH E 3 .   ? -30.403 14.924  10.076 1.00 39.22 ?  873  HOH A O    1 
HETATM 12374 O O    . HOH E 3 .   ? -41.927 24.129  20.836 1.00 33.24 ?  874  HOH A O    1 
HETATM 12375 O O    . HOH E 3 .   ? 7.612   14.710  8.828  1.00 39.85 ?  875  HOH A O    1 
HETATM 12376 O O    . HOH E 3 .   ? -28.013 7.129   37.287 1.00 23.30 ?  876  HOH A O    1 
HETATM 12377 O O    . HOH E 3 .   ? -6.414  33.678  12.892 1.00 32.66 ?  877  HOH A O    1 
HETATM 12378 O O    . HOH E 3 .   ? -0.756  25.648  6.803  1.00 33.72 ?  878  HOH A O    1 
HETATM 12379 O O    . HOH E 3 .   ? -10.782 32.711  25.187 1.00 37.36 ?  879  HOH A O    1 
HETATM 12380 O O    . HOH E 3 .   ? -22.485 37.068  13.673 1.00 30.32 ?  880  HOH A O    1 
HETATM 12381 O O    . HOH E 3 .   ? -23.847 10.522  6.454  1.00 26.35 ?  881  HOH A O    1 
HETATM 12382 O O    . HOH E 3 .   ? -31.545 30.751  28.130 1.00 28.75 ?  882  HOH A O    1 
HETATM 12383 O O    . HOH E 3 .   ? -6.896  15.549  2.663  1.00 29.02 ?  883  HOH A O    1 
HETATM 12384 O O    . HOH E 3 .   ? -6.493  14.849  36.574 1.00 34.31 ?  884  HOH A O    1 
HETATM 12385 O O    . HOH E 3 .   ? -28.798 3.547   42.470 1.00 39.17 ?  885  HOH A O    1 
HETATM 12386 O O    . HOH E 3 .   ? -28.482 11.486  11.217 1.00 20.27 ?  886  HOH A O    1 
HETATM 12387 O O    . HOH E 3 .   ? -23.501 -8.445  36.342 1.00 38.91 ?  887  HOH A O    1 
HETATM 12388 O O    . HOH E 3 .   ? 10.182  3.826   26.557 1.00 26.65 ?  888  HOH A O    1 
HETATM 12389 O O    . HOH E 3 .   ? -0.893  -1.366  11.672 1.00 32.66 ?  889  HOH A O    1 
HETATM 12390 O O    . HOH E 3 .   ? -9.660  12.913  33.655 1.00 14.30 ?  890  HOH A O    1 
HETATM 12391 O O    . HOH E 3 .   ? -35.124 19.043  26.876 1.00 16.80 ?  891  HOH A O    1 
HETATM 12392 O O    . HOH E 3 .   ? -7.901  8.480   45.567 1.00 33.35 ?  892  HOH A O    1 
HETATM 12393 O O    . HOH E 3 .   ? -6.425  25.580  6.304  1.00 34.00 ?  893  HOH A O    1 
HETATM 12394 O O    . HOH E 3 .   ? -7.834  24.931  25.742 1.00 15.42 ?  894  HOH A O    1 
HETATM 12395 O O    . HOH E 3 .   ? -18.116 0.998   13.810 1.00 25.45 ?  895  HOH A O    1 
HETATM 12396 O O    . HOH E 3 .   ? 17.294  11.177  30.386 1.00 43.16 ?  896  HOH A O    1 
HETATM 12397 O O    . HOH E 3 .   ? -16.053 13.091  34.101 1.00 16.84 ?  897  HOH A O    1 
HETATM 12398 O O    . HOH E 3 .   ? -34.697 19.482  16.189 1.00 22.91 ?  898  HOH A O    1 
HETATM 12399 O O    . HOH E 3 .   ? -21.906 13.135  36.939 1.00 19.32 ?  899  HOH A O    1 
HETATM 12400 O O    . HOH E 3 .   ? -8.817  28.596  27.190 1.00 35.53 ?  900  HOH A O    1 
HETATM 12401 O O    . HOH E 3 .   ? 1.718   -1.375  19.080 1.00 16.14 ?  901  HOH A O    1 
HETATM 12402 O O    . HOH E 3 .   ? -4.349  31.498  21.398 1.00 33.94 ?  902  HOH A O    1 
HETATM 12403 O O    . HOH E 3 .   ? -5.754  27.419  25.871 1.00 24.53 ?  903  HOH A O    1 
HETATM 12404 O O    . HOH E 3 .   ? -37.940 32.951  22.261 1.00 39.20 ?  904  HOH A O    1 
HETATM 12405 O O    . HOH E 3 .   ? 7.071   6.125   9.608  1.00 33.53 ?  905  HOH A O    1 
HETATM 12406 O O    . HOH E 3 .   ? 10.594  3.008   32.765 1.00 38.19 ?  906  HOH A O    1 
HETATM 12407 O O    . HOH E 3 .   ? 17.730  13.792  23.581 1.00 28.67 ?  907  HOH A O    1 
HETATM 12408 O O    . HOH E 3 .   ? -32.817 12.445  28.313 1.00 31.05 ?  908  HOH A O    1 
HETATM 12409 O O    . HOH E 3 .   ? 16.994  10.209  24.963 1.00 36.18 ?  909  HOH A O    1 
HETATM 12410 O O    . HOH E 3 .   ? -15.664 23.999  4.839  1.00 16.96 ?  910  HOH A O    1 
HETATM 12411 O O    . HOH E 3 .   ? -2.918  14.176  3.622  1.00 29.68 ?  911  HOH A O    1 
HETATM 12412 O O    . HOH E 3 .   ? -3.903  16.990  37.122 1.00 35.87 ?  912  HOH A O    1 
HETATM 12413 O O    . HOH E 3 .   ? 10.811  2.030   24.387 1.00 34.48 ?  913  HOH A O    1 
HETATM 12414 O O    . HOH E 3 .   ? -17.759 9.392   2.943  1.00 27.36 ?  914  HOH A O    1 
HETATM 12415 O O    . HOH E 3 .   ? -12.050 31.900  22.447 1.00 24.70 ?  915  HOH A O    1 
HETATM 12416 O O    . HOH E 3 .   ? -17.205 16.092  1.882  1.00 32.61 ?  916  HOH A O    1 
HETATM 12417 O O    . HOH E 3 .   ? -15.815 14.459  37.606 1.00 33.35 ?  917  HOH A O    1 
HETATM 12418 O O    . HOH E 3 .   ? 0.801   4.367   31.958 1.00 16.97 ?  918  HOH A O    1 
HETATM 12419 O O    . HOH E 3 .   ? 8.545   16.907  12.262 1.00 26.17 ?  919  HOH A O    1 
HETATM 12420 O O    . HOH E 3 .   ? -2.783  -7.473  13.763 1.00 39.43 ?  920  HOH A O    1 
HETATM 12421 O O    . HOH E 3 .   ? -27.665 11.359  8.834  1.00 29.89 ?  921  HOH A O    1 
HETATM 12422 O O    . HOH E 3 .   ? -32.327 13.987  16.544 1.00 34.95 ?  922  HOH A O    1 
HETATM 12423 O O    . HOH E 3 .   ? 15.510  13.844  27.713 1.00 24.00 ?  923  HOH A O    1 
HETATM 12424 O O    . HOH E 3 .   ? -13.305 13.436  34.599 1.00 13.96 ?  924  HOH A O    1 
HETATM 12425 O O    . HOH E 3 .   ? 6.311   -4.641  30.126 1.00 37.43 ?  925  HOH A O    1 
HETATM 12426 O O    . HOH E 3 .   ? 11.906  17.257  18.423 1.00 37.75 ?  926  HOH A O    1 
HETATM 12427 O O    . HOH E 3 .   ? 10.523  15.780  15.658 1.00 36.29 ?  927  HOH A O    1 
HETATM 12428 O O    . HOH E 3 .   ? -20.090 37.765  26.953 1.00 29.71 ?  928  HOH A O    1 
HETATM 12429 O O    . HOH E 3 .   ? -1.333  18.474  40.685 1.00 33.61 ?  929  HOH A O    1 
HETATM 12430 O O    . HOH E 3 .   ? -25.874 -2.098  43.029 1.00 28.46 ?  930  HOH A O    1 
HETATM 12431 O O    . HOH E 3 .   ? -25.995 -2.593  36.626 1.00 29.31 ?  931  HOH A O    1 
HETATM 12432 O O    . HOH E 3 .   ? -33.632 18.229  31.197 1.00 28.55 ?  932  HOH A O    1 
HETATM 12433 O O    . HOH E 3 .   ? 0.324   -4.722  22.411 1.00 27.03 ?  933  HOH A O    1 
HETATM 12434 O O    . HOH E 3 .   ? -34.705 28.125  19.813 1.00 18.09 ?  934  HOH A O    1 
HETATM 12435 O O    . HOH E 3 .   ? -35.365 15.926  21.848 1.00 33.31 ?  935  HOH A O    1 
HETATM 12436 O O    . HOH E 3 .   ? -26.275 7.461   18.583 1.00 21.92 ?  936  HOH A O    1 
HETATM 12437 O O    . HOH E 3 .   ? -25.621 33.787  15.039 1.00 36.84 ?  937  HOH A O    1 
HETATM 12438 O O    . HOH E 3 .   ? 4.110   4.103   10.010 1.00 37.99 ?  938  HOH A O    1 
HETATM 12439 O O    . HOH E 3 .   ? -25.076 -5.504  45.840 1.00 38.80 ?  939  HOH A O    1 
HETATM 12440 O O    . HOH E 3 .   ? -31.191 24.850  12.385 1.00 16.39 ?  940  HOH A O    1 
HETATM 12441 O O    . HOH E 3 .   ? -24.702 -5.429  37.369 1.00 27.17 ?  941  HOH A O    1 
HETATM 12442 O O    . HOH E 3 .   ? -9.574  23.010  8.243  1.00 11.86 ?  942  HOH A O    1 
HETATM 12443 O O    . HOH E 3 .   ? -11.311 32.298  18.554 1.00 16.41 ?  943  HOH A O    1 
HETATM 12444 O O    . HOH E 3 .   ? -10.706 11.233  38.176 1.00 23.32 ?  944  HOH A O    1 
HETATM 12445 O O    . HOH E 3 .   ? -21.961 38.441  20.216 1.00 38.53 ?  945  HOH A O    1 
HETATM 12446 O O    . HOH E 3 .   ? -5.657  21.164  6.984  1.00 26.60 ?  946  HOH A O    1 
HETATM 12447 O O    . HOH E 3 .   ? 18.006  16.190  20.024 1.00 43.64 ?  947  HOH A O    1 
HETATM 12448 O O    . HOH E 3 .   ? 9.056   18.789  49.573 1.00 40.24 ?  948  HOH A O    1 
HETATM 12449 O O    . HOH E 3 .   ? -8.997  25.601  7.461  1.00 15.65 ?  949  HOH A O    1 
HETATM 12450 O O    . HOH E 3 .   ? -26.094 2.794   49.782 1.00 41.31 ?  950  HOH A O    1 
HETATM 12451 O O    . HOH E 3 .   ? 11.276  23.600  24.541 1.00 34.17 ?  951  HOH A O    1 
HETATM 12452 O O    . HOH E 3 .   ? -11.332 -14.084 25.813 1.00 25.14 ?  952  HOH A O    1 
HETATM 12453 O O    . HOH E 3 .   ? -35.436 17.059  16.942 1.00 35.87 ?  953  HOH A O    1 
HETATM 12454 O O    . HOH E 3 .   ? -10.259 9.745   42.643 1.00 35.01 ?  954  HOH A O    1 
HETATM 12455 O O    . HOH E 3 .   ? -38.094 19.089  21.347 1.00 38.33 ?  955  HOH A O    1 
HETATM 12456 O O    . HOH E 3 .   ? 5.765   -1.304  27.426 1.00 37.98 ?  956  HOH A O    1 
HETATM 12457 O O    . HOH E 3 .   ? -7.620  14.704  34.106 1.00 20.67 ?  957  HOH A O    1 
HETATM 12458 O O    . HOH E 3 .   ? -20.988 -12.068 24.761 1.00 28.83 ?  958  HOH A O    1 
HETATM 12459 O O    . HOH E 3 .   ? -23.667 22.470  3.082  1.00 13.68 ?  959  HOH A O    1 
HETATM 12460 O O    . HOH E 3 .   ? -29.878 13.161  39.885 1.00 37.33 ?  960  HOH A O    1 
HETATM 12461 O O    . HOH E 3 .   ? -22.302 20.864  1.137  1.00 20.04 ?  961  HOH A O    1 
HETATM 12462 O O    . HOH E 3 .   ? -32.633 10.134  20.226 1.00 43.75 ?  962  HOH A O    1 
HETATM 12463 O O    . HOH E 3 .   ? -15.981 37.964  22.148 1.00 31.74 ?  963  HOH A O    1 
HETATM 12464 O O    . HOH E 3 .   ? -8.040  5.343   3.573  1.00 39.74 ?  964  HOH A O    1 
HETATM 12465 O O    . HOH E 3 .   ? -32.241 6.676   23.397 1.00 42.58 ?  965  HOH A O    1 
HETATM 12466 O O    . HOH E 3 .   ? -0.370  26.682  41.453 1.00 15.01 ?  966  HOH A O    1 
HETATM 12467 O O    . HOH E 3 .   ? -9.316  33.080  20.284 1.00 28.76 ?  967  HOH A O    1 
HETATM 12468 O O    . HOH E 3 .   ? 3.262   -3.420  18.797 1.00 38.43 ?  968  HOH A O    1 
HETATM 12469 O O    . HOH E 3 .   ? -11.813 29.004  7.441  1.00 18.01 ?  969  HOH A O    1 
HETATM 12470 O O    . HOH E 3 .   ? 8.241   16.299  32.721 1.00 24.34 ?  970  HOH A O    1 
HETATM 12471 O O    . HOH E 3 .   ? -8.554  13.861  2.240  1.00 41.40 ?  971  HOH A O    1 
HETATM 12472 O O    . HOH E 3 .   ? -25.492 30.188  29.596 1.00 22.49 ?  972  HOH A O    1 
HETATM 12473 O O    . HOH E 3 .   ? -30.486 9.092   15.874 1.00 28.47 ?  973  HOH A O    1 
HETATM 12474 O O    . HOH E 3 .   ? -30.858 4.456   35.913 1.00 26.55 ?  974  HOH A O    1 
HETATM 12475 O O    . HOH E 3 .   ? -26.029 33.925  12.918 1.00 35.96 ?  975  HOH A O    1 
HETATM 12476 O O    . HOH E 3 .   ? 1.749   -2.971  21.755 1.00 35.84 ?  976  HOH A O    1 
HETATM 12477 O O    . HOH E 3 .   ? 1.729   -5.638  25.049 1.00 30.88 ?  977  HOH A O    1 
HETATM 12478 O O    . HOH E 3 .   ? -17.276 -13.951 45.748 1.00 42.52 ?  978  HOH A O    1 
HETATM 12479 O O    . HOH E 3 .   ? 9.382   20.580  29.708 1.00 31.19 ?  979  HOH A O    1 
HETATM 12480 O O    . HOH E 3 .   ? -3.815  28.774  5.777  1.00 36.19 ?  980  HOH A O    1 
HETATM 12481 O O    . HOH E 3 .   ? -4.376  6.050   48.696 1.00 37.11 ?  981  HOH A O    1 
HETATM 12482 O O    . HOH E 3 .   ? -24.089 37.814  28.389 1.00 36.17 ?  982  HOH A O    1 
HETATM 12483 O O    . HOH E 3 .   ? -11.190 11.628  3.951  1.00 35.67 ?  983  HOH A O    1 
HETATM 12484 O O    . HOH E 3 .   ? -15.810 19.716  2.604  1.00 22.74 ?  984  HOH A O    1 
HETATM 12485 O O    . HOH E 3 .   ? -25.281 34.785  8.631  1.00 15.21 ?  985  HOH A O    1 
HETATM 12486 O O    . HOH E 3 .   ? -17.698 13.584  2.237  1.00 34.99 ?  986  HOH A O    1 
HETATM 12487 O O    . HOH E 3 .   ? -31.844 6.652   36.891 1.00 39.30 ?  987  HOH A O    1 
HETATM 12488 O O    . HOH E 3 .   ? -28.386 31.943  17.218 1.00 34.49 ?  988  HOH A O    1 
HETATM 12489 O O    . HOH E 3 .   ? 5.189   13.812  6.977  1.00 30.13 ?  989  HOH A O    1 
HETATM 12490 O O    . HOH E 3 .   ? -2.284  6.465   5.270  1.00 32.18 ?  990  HOH A O    1 
HETATM 12491 O O    . HOH E 3 .   ? -3.384  18.155  8.995  1.00 23.80 ?  991  HOH A O    1 
HETATM 12492 O O    . HOH E 3 .   ? -5.396  19.772  9.021  1.00 30.82 ?  992  HOH A O    1 
HETATM 12493 O O    . HOH E 3 .   ? 7.141   22.776  32.573 1.00 23.43 ?  993  HOH A O    1 
HETATM 12494 O O    . HOH E 3 .   ? -17.729 19.457  0.628  1.00 33.85 ?  994  HOH A O    1 
HETATM 12495 O O    . HOH E 3 .   ? -8.125  -14.136 44.695 1.00 29.08 ?  995  HOH A O    1 
HETATM 12496 O O    . HOH E 3 .   ? 8.921   18.510  36.732 1.00 38.62 ?  996  HOH A O    1 
HETATM 12497 O O    . HOH E 3 .   ? -9.947  13.381  36.442 1.00 23.68 ?  997  HOH A O    1 
HETATM 12498 O O    . HOH E 3 .   ? 17.347  13.245  29.441 1.00 35.74 ?  998  HOH A O    1 
HETATM 12499 O O    . HOH E 3 .   ? -22.364 30.935  32.149 1.00 29.68 ?  999  HOH A O    1 
HETATM 12500 O O    . HOH E 3 .   ? -3.010  -5.152  49.551 1.00 38.27 ?  1000 HOH A O    1 
HETATM 12501 O O    . HOH E 3 .   ? -27.110 -8.873  44.143 1.00 44.15 ?  1001 HOH A O    1 
HETATM 12502 O O    . HOH E 3 .   ? -18.139 6.450   49.380 1.00 40.83 ?  1002 HOH A O    1 
HETATM 12503 O O    . HOH E 3 .   ? -26.952 -1.300  34.333 1.00 27.45 ?  1003 HOH A O    1 
HETATM 12504 O O    . HOH E 3 .   ? -36.593 18.066  23.119 1.00 21.31 ?  1004 HOH A O    1 
HETATM 12505 O O    . HOH E 3 .   ? 3.653   6.586   6.201  1.00 41.80 ?  1005 HOH A O    1 
HETATM 12506 O O    . HOH E 3 .   ? -0.401  24.330  49.778 1.00 36.55 ?  1006 HOH A O    1 
HETATM 12507 O O    . HOH E 3 .   ? -5.049  -22.422 30.842 1.00 34.80 ?  1007 HOH A O    1 
HETATM 12508 O O    . HOH E 3 .   ? 7.907   -0.725  27.834 1.00 36.82 ?  1008 HOH A O    1 
HETATM 12509 O O    . HOH E 3 .   ? -13.479 -18.273 40.395 1.00 40.21 ?  1009 HOH A O    1 
HETATM 12510 O O    . HOH E 3 .   ? -5.408  5.398   5.409  1.00 33.07 ?  1010 HOH A O    1 
HETATM 12511 O O    . HOH E 3 .   ? -21.921 10.234  4.583  1.00 27.59 ?  1011 HOH A O    1 
HETATM 12512 O O    . HOH E 3 .   ? 12.479  16.855  29.914 1.00 38.58 ?  1012 HOH A O    1 
HETATM 12513 O O    . HOH E 3 .   ? -7.126  1.158   4.444  1.00 41.18 ?  1013 HOH A O    1 
HETATM 12514 O O    . HOH E 3 .   ? -13.840 -18.359 36.295 1.00 31.00 ?  1014 HOH A O    1 
HETATM 12515 O O    . HOH E 3 .   ? 9.652   8.745   37.511 1.00 32.67 ?  1015 HOH A O    1 
HETATM 12516 O O    . HOH E 3 .   ? -27.153 -2.083  39.053 1.00 26.20 ?  1016 HOH A O    1 
HETATM 12517 O O    . HOH E 3 .   ? -27.370 -2.001  29.755 1.00 35.71 ?  1017 HOH A O    1 
HETATM 12518 O O    . HOH E 3 .   ? -8.320  14.146  40.616 1.00 39.88 ?  1018 HOH A O    1 
HETATM 12519 O O    . HOH E 3 .   ? 3.825   -2.560  47.702 1.00 38.31 ?  1019 HOH A O    1 
HETATM 12520 O O    . HOH E 3 .   ? 7.901   20.437  37.734 1.00 37.76 ?  1020 HOH A O    1 
HETATM 12521 O O    . HOH E 3 .   ? 1.036   15.176  6.693  1.00 26.33 ?  1021 HOH A O    1 
HETATM 12522 O O    . HOH E 3 .   ? -13.727 18.021  2.069  1.00 28.17 ?  1022 HOH A O    1 
HETATM 12523 O O    . HOH E 3 .   ? -13.148 26.696  35.685 1.00 26.79 ?  1023 HOH A O    1 
HETATM 12524 O O    . HOH E 3 .   ? 9.774   14.239  33.409 1.00 38.96 ?  1024 HOH A O    1 
HETATM 12525 O O    . HOH E 3 .   ? -8.332  12.644  38.404 1.00 34.60 ?  1025 HOH A O    1 
HETATM 12526 O O    . HOH E 3 .   ? -25.165 -5.853  47.998 1.00 44.42 ?  1026 HOH A O    1 
HETATM 12527 O O    . HOH E 3 .   ? -28.042 15.345  39.709 1.00 23.20 ?  1027 HOH A O    1 
HETATM 12528 O O    . HOH E 3 .   ? 11.190  10.388  35.539 1.00 43.48 ?  1028 HOH A O    1 
HETATM 12529 O O    . HOH E 3 .   ? -32.695 9.558   17.450 1.00 38.27 ?  1029 HOH A O    1 
HETATM 12530 O O    . HOH E 3 .   ? 11.473  11.818  14.481 1.00 19.31 ?  1030 HOH A O    1 
HETATM 12531 O O    . HOH E 3 .   ? -30.875 11.243  13.534 1.00 40.31 ?  1031 HOH A O    1 
HETATM 12532 O O    . HOH E 3 .   ? -30.235 7.588   38.866 1.00 33.12 ?  1032 HOH A O    1 
HETATM 12533 O O    . HOH E 3 .   ? 9.356   0.541   31.234 1.00 39.92 ?  1033 HOH A O    1 
HETATM 12534 O O    . HOH E 3 .   ? -5.083  -14.116 22.771 1.00 15.78 ?  1034 HOH A O    1 
HETATM 12535 O O    . HOH E 3 .   ? 12.198  21.439  21.838 1.00 34.22 ?  1035 HOH A O    1 
HETATM 12536 O O    . HOH E 3 .   ? -17.930 0.954   10.434 1.00 41.62 ?  1036 HOH A O    1 
HETATM 12537 O O    . HOH E 3 .   ? -11.669 7.356   1.767  1.00 41.31 ?  1037 HOH A O    1 
HETATM 12538 O O    . HOH E 3 .   ? -21.915 28.015  33.437 1.00 24.97 ?  1038 HOH A O    1 
HETATM 12539 O O    . HOH E 3 .   ? -33.069 12.759  25.328 1.00 30.57 ?  1039 HOH A O    1 
HETATM 12540 O O    . HOH E 3 .   ? 12.084  13.877  16.178 1.00 31.13 ?  1040 HOH A O    1 
HETATM 12541 O O    . HOH E 3 .   ? -20.895 -14.907 33.335 1.00 32.77 ?  1041 HOH A O    1 
HETATM 12542 O O    . HOH E 3 .   ? -17.868 13.262  36.031 1.00 24.84 ?  1042 HOH A O    1 
HETATM 12543 O O    . HOH E 3 .   ? -14.682 23.878  33.386 1.00 26.26 ?  1043 HOH A O    1 
HETATM 12544 O O    . HOH E 3 .   ? -19.851 21.466  0.451  1.00 22.74 ?  1044 HOH A O    1 
HETATM 12545 O O    . HOH E 3 .   ? 12.026  13.784  32.688 1.00 31.00 ?  1045 HOH A O    1 
HETATM 12546 O O    . HOH E 3 .   ? 3.133   15.341  8.226  1.00 19.94 ?  1046 HOH A O    1 
HETATM 12547 O O    . HOH E 3 .   ? -13.884 22.995  0.982  1.00 33.09 ?  1047 HOH A O    1 
HETATM 12548 O O    . HOH E 3 .   ? -33.159 14.357  30.432 1.00 27.48 ?  1048 HOH A O    1 
HETATM 12549 O O    . HOH E 3 .   ? 2.279   19.300  6.350  1.00 30.98 ?  1049 HOH A O    1 
HETATM 12550 O O    . HOH E 3 .   ? -15.237 10.489  2.447  1.00 38.79 ?  1050 HOH A O    1 
HETATM 12551 O O    . HOH E 3 .   ? -16.014 22.355  2.666  1.00 19.27 ?  1051 HOH A O    1 
HETATM 12552 O O    . HOH E 3 .   ? -34.737 14.861  24.738 1.00 21.02 ?  1052 HOH A O    1 
HETATM 12553 O O    . HOH E 3 .   ? 8.805   20.685  32.513 1.00 27.20 ?  1053 HOH A O    1 
HETATM 12554 O O    . HOH E 3 .   ? -32.206 29.707  19.030 1.00 32.20 ?  1054 HOH A O    1 
HETATM 12555 O O    . HOH E 3 .   ? -7.907  8.682   3.711  1.00 24.31 ?  1055 HOH A O    1 
HETATM 12556 O O    . HOH E 3 .   ? -1.941  23.305  39.966 1.00 28.19 ?  1056 HOH A O    1 
HETATM 12557 O O    . HOH E 3 .   ? -4.822  -16.282 24.452 1.00 20.60 ?  1057 HOH A O    1 
HETATM 12558 O O    . HOH E 3 .   ? 10.462  9.173   40.135 1.00 40.45 ?  1058 HOH A O    1 
HETATM 12559 O O    . HOH E 3 .   ? 6.906   19.482  39.997 1.00 29.25 ?  1059 HOH A O    1 
HETATM 12560 O O    . HOH E 3 .   ? 4.443   17.830  8.056  1.00 24.88 ?  1060 HOH A O    1 
HETATM 12561 O O    . HOH E 3 .   ? -4.835  -21.748 32.841 1.00 39.52 ?  1061 HOH A O    1 
HETATM 12562 O O    . HOH E 3 .   ? -31.407 13.349  37.427 1.00 36.66 ?  1062 HOH A O    1 
HETATM 12563 O O    . HOH E 3 .   ? 9.300   3.060   29.052 1.00 27.75 ?  1063 HOH A O    1 
HETATM 12564 O O    . HOH E 3 .   ? -13.085 24.517  5.689  1.00 15.02 ?  1064 HOH A O    1 
HETATM 12565 O O    . HOH E 3 .   ? -16.423 35.733  18.112 1.00 18.20 ?  1065 HOH A O    1 
HETATM 12566 O O    . HOH E 3 .   ? 5.170   9.543   5.320  1.00 40.25 ?  1066 HOH A O    1 
HETATM 12567 O O    . HOH E 3 .   ? 6.424   17.294  52.276 1.00 37.07 ?  1067 HOH A O    1 
HETATM 12568 O O    . HOH E 3 .   ? -7.088  12.475  1.510  1.00 43.10 ?  1068 HOH A O    1 
HETATM 12569 O O    . HOH E 3 .   ? -22.298 -14.194 25.051 1.00 30.42 ?  1069 HOH A O    1 
HETATM 12570 O O    . HOH E 3 .   ? 2.084   14.250  4.255  1.00 36.17 ?  1070 HOH A O    1 
HETATM 12571 O O    . HOH E 3 .   ? 16.373  16.197  26.732 1.00 26.06 ?  1071 HOH A O    1 
HETATM 12572 O O    . HOH E 3 .   ? -10.829 28.963  4.411  1.00 39.37 ?  1072 HOH A O    1 
HETATM 12573 O O    . HOH E 3 .   ? -14.882 34.345  20.128 1.00 18.60 ?  1073 HOH A O    1 
HETATM 12574 O O    . HOH E 3 .   ? -11.515 17.222  33.246 1.00 13.85 ?  1074 HOH A O    1 
HETATM 12575 O O    . HOH E 3 .   ? 15.930  17.263  24.556 1.00 24.33 ?  1075 HOH A O    1 
HETATM 12576 O O    . HOH E 3 .   ? -35.642 16.345  26.966 1.00 21.24 ?  1076 HOH A O    1 
HETATM 12577 O O    . HOH E 3 .   ? -8.991  10.832  2.249  1.00 38.48 ?  1077 HOH A O    1 
HETATM 12578 O O    . HOH E 3 .   ? -32.813 3.376   35.598 1.00 42.02 ?  1078 HOH A O    1 
HETATM 12579 O O    . HOH E 3 .   ? 0.304   17.368  6.322  1.00 36.14 ?  1079 HOH A O    1 
HETATM 12580 O O    . HOH E 3 .   ? -35.190 15.202  29.408 1.00 29.13 ?  1080 HOH A O    1 
HETATM 12581 O O    . HOH E 3 .   ? -13.981 17.631  34.307 1.00 13.81 ?  1081 HOH A O    1 
HETATM 12582 O O    . HOH E 3 .   ? -12.592 35.891  19.666 1.00 24.49 ?  1082 HOH A O    1 
HETATM 12583 O O    . HOH E 3 .   ? -16.517 38.168  19.373 1.00 29.48 ?  1083 HOH A O    1 
HETATM 12584 O O    . HOH E 3 .   ? -13.987 15.675  36.165 1.00 26.94 ?  1084 HOH A O    1 
HETATM 12585 O O    . HOH E 3 .   ? -4.052  23.161  43.539 1.00 33.70 ?  1085 HOH A O    1 
HETATM 12586 O O    . HOH E 3 .   ? 3.089   33.985  24.764 1.00 36.60 ?  1086 HOH A O    1 
HETATM 12587 O O    . HOH E 3 .   ? -5.277  23.193  45.725 1.00 43.61 ?  1087 HOH A O    1 
HETATM 12588 O O    . HOH E 3 .   ? -3.586  25.664  42.603 1.00 27.27 ?  1088 HOH A O    1 
HETATM 12589 O O    . HOH E 3 .   ? -7.797  18.750  34.999 1.00 33.27 ?  1089 HOH A O    1 
HETATM 12590 O O    . HOH E 3 .   ? -9.456  16.853  35.015 1.00 22.54 ?  1090 HOH A O    1 
HETATM 12591 O O    . HOH E 3 .   ? 9.087   32.831  23.595 1.00 35.86 ?  1091 HOH A O    1 
HETATM 12592 O O    . HOH E 3 .   ? -10.926 15.901  37.024 1.00 36.66 ?  1092 HOH A O    1 
HETATM 12593 O O    . HOH E 3 .   ? -9.615  20.741  34.428 1.00 20.02 ?  1093 HOH A O    1 
HETATM 12594 O O    . HOH E 3 .   ? -9.015  23.521  34.997 1.00 20.10 ?  1094 HOH A O    1 
HETATM 12595 O O    . HOH E 3 .   ? -5.888  25.623  41.244 1.00 33.22 ?  1095 HOH A O    1 
HETATM 12596 O O    . HOH F 3 .   ? -28.010 42.830  49.813 1.00 44.87 ?  401  HOH B O    1 
HETATM 12597 O O    . HOH F 3 .   ? -31.550 33.744  57.796 1.00 32.97 ?  402  HOH B O    1 
HETATM 12598 O O    . HOH F 3 .   ? -15.234 25.746  54.110 1.00 32.01 ?  403  HOH B O    1 
HETATM 12599 O O    . HOH F 3 .   ? -4.687  56.778  42.555 1.00 3.89  ?  404  HOH B O    1 
HETATM 12600 O O    . HOH F 3 .   ? 14.173  23.493  26.869 1.00 36.79 ?  405  HOH B O    1 
HETATM 12601 O O    . HOH F 3 .   ? 5.629   28.773  60.864 1.00 4.47  ?  406  HOH B O    1 
HETATM 12602 O O    . HOH F 3 .   ? 16.710  35.357  26.638 1.00 33.24 ?  407  HOH B O    1 
HETATM 12603 O O    . HOH F 3 .   ? -8.337  27.670  78.762 1.00 28.09 ?  408  HOH B O    1 
HETATM 12604 O O    . HOH F 3 .   ? -2.742  60.682  53.397 1.00 34.36 ?  409  HOH B O    1 
HETATM 12605 O O    . HOH F 3 .   ? -15.032 20.823  56.518 1.00 40.81 ?  410  HOH B O    1 
HETATM 12606 O O    . HOH F 3 .   ? 12.393  31.906  58.467 1.00 15.48 ?  411  HOH B O    1 
HETATM 12607 O O    . HOH F 3 .   ? -29.481 25.678  37.798 1.00 34.57 ?  412  HOH B O    1 
HETATM 12608 O O    . HOH F 3 .   ? 10.592  38.539  20.880 1.00 34.60 ?  413  HOH B O    1 
HETATM 12609 O O    . HOH F 3 .   ? 6.861   28.555  26.110 1.00 26.49 ?  414  HOH B O    1 
HETATM 12610 O O    . HOH F 3 .   ? -22.541 20.214  48.840 1.00 38.33 ?  415  HOH B O    1 
HETATM 12611 O O    . HOH F 3 .   ? -5.139  16.807  57.053 1.00 30.33 ?  416  HOH B O    1 
HETATM 12612 O O    . HOH F 3 .   ? -12.672 24.549  56.883 1.00 19.62 ?  417  HOH B O    1 
HETATM 12613 O O    . HOH F 3 .   ? -30.138 36.643  52.607 1.00 32.22 ?  418  HOH B O    1 
HETATM 12614 O O    . HOH F 3 .   ? -18.512 23.528  59.037 1.00 30.51 ?  419  HOH B O    1 
HETATM 12615 O O    . HOH F 3 .   ? -9.236  38.497  24.654 1.00 30.56 ?  420  HOH B O    1 
HETATM 12616 O O    . HOH F 3 .   ? 10.565  24.309  52.255 1.00 26.59 ?  421  HOH B O    1 
HETATM 12617 O O    . HOH F 3 .   ? 15.814  25.577  48.377 1.00 26.37 ?  422  HOH B O    1 
HETATM 12618 O O    . HOH F 3 .   ? -18.256 37.384  52.540 1.00 24.17 ?  423  HOH B O    1 
HETATM 12619 O O    . HOH F 3 .   ? -13.537 26.388  53.697 1.00 22.05 ?  424  HOH B O    1 
HETATM 12620 O O    . HOH F 3 .   ? -23.340 31.868  70.509 1.00 21.69 ?  425  HOH B O    1 
HETATM 12621 O O    . HOH F 3 .   ? -32.084 23.049  51.084 1.00 33.03 ?  426  HOH B O    1 
HETATM 12622 O O    . HOH F 3 .   ? -11.587 56.237  54.068 1.00 30.70 ?  427  HOH B O    1 
HETATM 12623 O O    . HOH F 3 .   ? 16.153  43.493  25.960 1.00 35.86 ?  428  HOH B O    1 
HETATM 12624 O O    . HOH F 3 .   ? -20.627 41.726  30.048 1.00 33.18 ?  429  HOH B O    1 
HETATM 12625 O O    . HOH F 3 .   ? -10.183 50.009  25.852 1.00 24.70 ?  430  HOH B O    1 
HETATM 12626 O O    . HOH F 3 .   ? 18.126  46.986  40.682 1.00 36.13 ?  431  HOH B O    1 
HETATM 12627 O O    . HOH F 3 .   ? -26.935 42.263  45.669 1.00 30.51 ?  432  HOH B O    1 
HETATM 12628 O O    . HOH F 3 .   ? -4.228  43.176  37.653 1.00 8.74  ?  433  HOH B O    1 
HETATM 12629 O O    . HOH F 3 .   ? 0.046   53.402  57.626 1.00 20.48 ?  434  HOH B O    1 
HETATM 12630 O O    . HOH F 3 .   ? 5.104   58.371  44.955 1.00 36.75 ?  435  HOH B O    1 
HETATM 12631 O O    . HOH F 3 .   ? -15.345 31.469  76.883 1.00 35.83 ?  436  HOH B O    1 
HETATM 12632 O O    . HOH F 3 .   ? 12.107  35.993  39.393 1.00 21.67 ?  437  HOH B O    1 
HETATM 12633 O O    . HOH F 3 .   ? 9.941   22.648  50.144 1.00 24.03 ?  438  HOH B O    1 
HETATM 12634 O O    . HOH F 3 .   ? -33.809 29.200  39.992 1.00 17.58 ?  439  HOH B O    1 
HETATM 12635 O O    . HOH F 3 .   ? -23.713 15.265  37.538 1.00 20.18 ?  440  HOH B O    1 
HETATM 12636 O O    . HOH F 3 .   ? 26.075  32.125  42.847 1.00 34.32 ?  441  HOH B O    1 
HETATM 12637 O O    . HOH F 3 .   ? -10.668 20.895  62.371 1.00 23.65 ?  442  HOH B O    1 
HETATM 12638 O O    . HOH F 3 .   ? 18.441  29.637  47.411 1.00 19.00 ?  443  HOH B O    1 
HETATM 12639 O O    . HOH F 3 .   ? 2.023   56.363  54.809 1.00 38.54 ?  444  HOH B O    1 
HETATM 12640 O O    . HOH F 3 .   ? -26.596 31.043  43.421 1.00 22.10 ?  445  HOH B O    1 
HETATM 12641 O O    . HOH F 3 .   ? 0.141   46.848  35.116 1.00 11.88 ?  446  HOH B O    1 
HETATM 12642 O O    . HOH F 3 .   ? -25.759 34.665  44.017 1.00 23.93 ?  447  HOH B O    1 
HETATM 12643 O O    . HOH F 3 .   ? 0.969   24.076  66.457 1.00 15.85 ?  448  HOH B O    1 
HETATM 12644 O O    . HOH F 3 .   ? -22.396 51.984  36.587 1.00 21.13 ?  449  HOH B O    1 
HETATM 12645 O O    . HOH F 3 .   ? -29.129 40.095  38.226 1.00 29.84 ?  450  HOH B O    1 
HETATM 12646 O O    . HOH F 3 .   ? -4.881  39.367  25.731 1.00 39.25 ?  451  HOH B O    1 
HETATM 12647 O O    . HOH F 3 .   ? -17.811 51.096  29.208 1.00 17.82 ?  452  HOH B O    1 
HETATM 12648 O O    . HOH F 3 .   ? -22.922 32.735  73.154 1.00 35.87 ?  453  HOH B O    1 
HETATM 12649 O O    . HOH F 3 .   ? 6.657   44.070  21.474 1.00 26.78 ?  454  HOH B O    1 
HETATM 12650 O O    . HOH F 3 .   ? -11.903 24.174  59.608 1.00 18.08 ?  455  HOH B O    1 
HETATM 12651 O O    . HOH F 3 .   ? 3.660   59.818  52.331 1.00 28.78 ?  456  HOH B O    1 
HETATM 12652 O O    . HOH F 3 .   ? -17.326 34.244  44.839 1.00 8.28  ?  457  HOH B O    1 
HETATM 12653 O O    . HOH F 3 .   ? 13.969  48.312  53.595 1.00 43.32 ?  458  HOH B O    1 
HETATM 12654 O O    . HOH F 3 .   ? 0.542   49.372  66.030 1.00 31.63 ?  459  HOH B O    1 
HETATM 12655 O O    . HOH F 3 .   ? -22.477 44.032  56.167 1.00 13.90 ?  460  HOH B O    1 
HETATM 12656 O O    . HOH F 3 .   ? 27.525  28.620  42.801 1.00 20.04 ?  461  HOH B O    1 
HETATM 12657 O O    . HOH F 3 .   ? -8.292  60.558  55.159 1.00 40.17 ?  462  HOH B O    1 
HETATM 12658 O O    . HOH F 3 .   ? 15.781  40.622  25.793 1.00 23.32 ?  463  HOH B O    1 
HETATM 12659 O O    . HOH F 3 .   ? -8.247  40.364  67.425 1.00 13.38 ?  464  HOH B O    1 
HETATM 12660 O O    . HOH F 3 .   ? 2.769   52.418  32.502 1.00 24.22 ?  465  HOH B O    1 
HETATM 12661 O O    . HOH F 3 .   ? 4.969   47.661  20.386 1.00 36.24 ?  466  HOH B O    1 
HETATM 12662 O O    . HOH F 3 .   ? 3.667   30.925  27.115 1.00 23.74 ?  467  HOH B O    1 
HETATM 12663 O O    . HOH F 3 .   ? -30.829 32.199  54.875 1.00 26.70 ?  468  HOH B O    1 
HETATM 12664 O O    . HOH F 3 .   ? -2.955  41.064  26.459 1.00 29.72 ?  469  HOH B O    1 
HETATM 12665 O O    . HOH F 3 .   ? -15.674 54.660  58.063 1.00 23.76 ?  470  HOH B O    1 
HETATM 12666 O O    . HOH F 3 .   ? -19.313 46.959  58.096 1.00 14.01 ?  471  HOH B O    1 
HETATM 12667 O O    . HOH F 3 .   ? -3.541  60.724  37.979 1.00 37.01 ?  472  HOH B O    1 
HETATM 12668 O O    . HOH F 3 .   ? -9.149  18.416  57.347 1.00 33.39 ?  473  HOH B O    1 
HETATM 12669 O O    . HOH F 3 .   ? -15.456 37.449  43.341 1.00 12.30 ?  474  HOH B O    1 
HETATM 12670 O O    . HOH F 3 .   ? -20.219 35.930  50.206 1.00 19.19 ?  475  HOH B O    1 
HETATM 12671 O O    . HOH F 3 .   ? -8.049  55.206  37.894 1.00 11.02 ?  476  HOH B O    1 
HETATM 12672 O O    . HOH F 3 .   ? -29.231 36.803  46.221 1.00 28.78 ?  477  HOH B O    1 
HETATM 12673 O O    . HOH F 3 .   ? -4.756  37.000  33.726 1.00 9.96  ?  478  HOH B O    1 
HETATM 12674 O O    . HOH F 3 .   ? -26.547 42.334  36.511 1.00 15.29 ?  479  HOH B O    1 
HETATM 12675 O O    . HOH F 3 .   ? 17.391  49.235  34.571 1.00 24.35 ?  480  HOH B O    1 
HETATM 12676 O O    . HOH F 3 .   ? 10.824  52.145  37.513 1.00 16.10 ?  481  HOH B O    1 
HETATM 12677 O O    . HOH F 3 .   ? -20.006 48.938  33.369 1.00 19.16 ?  482  HOH B O    1 
HETATM 12678 O O    . HOH F 3 .   ? -27.908 22.021  44.964 1.00 29.62 ?  483  HOH B O    1 
HETATM 12679 O O    . HOH F 3 .   ? 1.328   34.311  30.110 1.00 23.15 ?  484  HOH B O    1 
HETATM 12680 O O    . HOH F 3 .   ? 16.609  34.207  53.622 1.00 29.37 ?  485  HOH B O    1 
HETATM 12681 O O    . HOH F 3 .   ? 1.913   39.395  33.455 1.00 8.55  ?  486  HOH B O    1 
HETATM 12682 O O    . HOH F 3 .   ? -18.008 32.035  33.980 1.00 11.66 ?  487  HOH B O    1 
HETATM 12683 O O    . HOH F 3 .   ? 15.336  30.115  61.308 1.00 33.31 ?  488  HOH B O    1 
HETATM 12684 O O    . HOH F 3 .   ? -23.627 41.477  60.159 1.00 13.14 ?  489  HOH B O    1 
HETATM 12685 O O    . HOH F 3 .   ? 4.348   56.543  38.362 1.00 26.13 ?  490  HOH B O    1 
HETATM 12686 O O    . HOH F 3 .   ? -21.832 50.770  34.440 1.00 22.51 ?  491  HOH B O    1 
HETATM 12687 O O    . HOH F 3 .   ? 4.602   38.749  24.507 1.00 22.50 ?  492  HOH B O    1 
HETATM 12688 O O    . HOH F 3 .   ? -10.171 47.292  66.670 1.00 16.16 ?  493  HOH B O    1 
HETATM 12689 O O    . HOH F 3 .   ? 14.346  45.652  52.167 1.00 23.62 ?  494  HOH B O    1 
HETATM 12690 O O    . HOH F 3 .   ? -34.444 26.939  52.278 1.00 26.77 ?  495  HOH B O    1 
HETATM 12691 O O    . HOH F 3 .   ? -22.207 40.110  49.438 1.00 17.93 ?  496  HOH B O    1 
HETATM 12692 O O    . HOH F 3 .   ? -0.492  30.142  29.466 1.00 22.15 ?  497  HOH B O    1 
HETATM 12693 O O    . HOH F 3 .   ? 0.465   33.898  45.312 1.00 10.46 ?  498  HOH B O    1 
HETATM 12694 O O    . HOH F 3 .   ? 1.273   48.494  25.290 1.00 26.17 ?  499  HOH B O    1 
HETATM 12695 O O    . HOH F 3 .   ? 14.432  23.808  35.427 1.00 21.41 ?  500  HOH B O    1 
HETATM 12696 O O    . HOH F 3 .   ? -9.817  57.284  47.869 1.00 24.76 ?  501  HOH B O    1 
HETATM 12697 O O    . HOH F 3 .   ? -22.324 38.359  35.220 1.00 21.83 ?  502  HOH B O    1 
HETATM 12698 O O    . HOH F 3 .   ? -23.728 50.811  45.700 1.00 19.00 ?  503  HOH B O    1 
HETATM 12699 O O    . HOH F 3 .   ? -21.439 49.389  65.600 1.00 27.45 ?  504  HOH B O    1 
HETATM 12700 O O    . HOH F 3 .   ? -4.385  40.403  33.177 1.00 8.84  ?  505  HOH B O    1 
HETATM 12701 O O    . HOH F 3 .   ? -21.101 43.821  30.069 1.00 28.55 ?  506  HOH B O    1 
HETATM 12702 O O    . HOH F 3 .   ? 11.444  30.459  45.916 1.00 10.93 ?  507  HOH B O    1 
HETATM 12703 O O    . HOH F 3 .   ? -6.319  30.996  45.903 1.00 12.69 ?  508  HOH B O    1 
HETATM 12704 O O    . HOH F 3 .   ? -1.875  28.495  71.572 1.00 18.59 ?  509  HOH B O    1 
HETATM 12705 O O    . HOH F 3 .   ? -10.409 52.260  30.022 1.00 15.48 ?  510  HOH B O    1 
HETATM 12706 O O    . HOH F 3 .   ? 11.000  34.960  61.501 1.00 24.91 ?  511  HOH B O    1 
HETATM 12707 O O    . HOH F 3 .   ? -19.808 14.544  34.434 1.00 11.85 ?  512  HOH B O    1 
HETATM 12708 O O    . HOH F 3 .   ? -0.334  57.090  35.646 1.00 21.38 ?  513  HOH B O    1 
HETATM 12709 O O    . HOH F 3 .   ? -27.482 29.415  60.885 1.00 21.05 ?  514  HOH B O    1 
HETATM 12710 O O    . HOH F 3 .   ? -5.514  20.447  53.412 1.00 27.41 ?  515  HOH B O    1 
HETATM 12711 O O    . HOH F 3 .   ? -18.203 43.373  25.818 1.00 20.75 ?  516  HOH B O    1 
HETATM 12712 O O    . HOH F 3 .   ? 5.486   24.742  38.154 1.00 17.39 ?  517  HOH B O    1 
HETATM 12713 O O    . HOH F 3 .   ? -2.401  17.246  57.753 1.00 26.40 ?  518  HOH B O    1 
HETATM 12714 O O    . HOH F 3 .   ? 13.305  33.170  52.386 1.00 18.59 ?  519  HOH B O    1 
HETATM 12715 O O    . HOH F 3 .   ? -28.172 43.408  43.079 1.00 29.67 ?  520  HOH B O    1 
HETATM 12716 O O    . HOH F 3 .   ? 3.576   18.497  61.397 1.00 22.42 ?  521  HOH B O    1 
HETATM 12717 O O    . HOH F 3 .   ? -17.313 49.443  33.021 1.00 16.67 ?  522  HOH B O    1 
HETATM 12718 O O    . HOH F 3 .   ? 19.940  31.154  31.994 1.00 23.98 ?  523  HOH B O    1 
HETATM 12719 O O    . HOH F 3 .   ? 0.920   46.040  32.602 1.00 10.40 ?  524  HOH B O    1 
HETATM 12720 O O    . HOH F 3 .   ? -13.023 24.583  75.869 1.00 20.57 ?  525  HOH B O    1 
HETATM 12721 O O    . HOH F 3 .   ? 0.306   49.610  34.682 1.00 11.99 ?  526  HOH B O    1 
HETATM 12722 O O    . HOH F 3 .   ? 16.653  34.211  33.659 1.00 15.26 ?  527  HOH B O    1 
HETATM 12723 O O    . HOH F 3 .   ? -20.004 22.555  38.416 1.00 37.66 ?  528  HOH B O    1 
HETATM 12724 O O    . HOH F 3 .   ? -1.834  37.937  27.077 1.00 15.03 ?  529  HOH B O    1 
HETATM 12725 O O    . HOH F 3 .   ? 25.064  30.553  39.619 1.00 25.01 ?  530  HOH B O    1 
HETATM 12726 O O    . HOH F 3 .   ? -13.983 52.430  51.838 1.00 11.58 ?  531  HOH B O    1 
HETATM 12727 O O    . HOH F 3 .   ? -3.513  36.535  69.946 1.00 21.18 ?  532  HOH B O    1 
HETATM 12728 O O    . HOH F 3 .   ? -20.797 39.965  28.748 1.00 33.48 ?  533  HOH B O    1 
HETATM 12729 O O    . HOH F 3 .   ? -0.356  22.450  69.492 1.00 11.49 ?  534  HOH B O    1 
HETATM 12730 O O    . HOH F 3 .   ? -6.814  47.873  25.862 1.00 15.21 ?  535  HOH B O    1 
HETATM 12731 O O    . HOH F 3 .   ? -15.827 46.049  23.320 1.00 20.55 ?  536  HOH B O    1 
HETATM 12732 O O    . HOH F 3 .   ? -3.789  52.412  26.946 1.00 38.17 ?  537  HOH B O    1 
HETATM 12733 O O    . HOH F 3 .   ? -18.244 37.711  30.832 1.00 19.25 ?  538  HOH B O    1 
HETATM 12734 O O    . HOH F 3 .   ? 1.110   39.078  36.067 1.00 9.09  ?  539  HOH B O    1 
HETATM 12735 O O    . HOH F 3 .   ? 11.213  41.046  60.221 1.00 39.73 ?  540  HOH B O    1 
HETATM 12736 O O    . HOH F 3 .   ? -10.129 34.594  30.464 1.00 15.99 ?  541  HOH B O    1 
HETATM 12737 O O    . HOH F 3 .   ? -10.963 45.535  69.956 1.00 23.15 ?  542  HOH B O    1 
HETATM 12738 O O    . HOH F 3 .   ? 3.953   52.395  52.608 1.00 13.99 ?  543  HOH B O    1 
HETATM 12739 O O    . HOH F 3 .   ? -27.421 32.040  64.192 1.00 17.48 ?  544  HOH B O    1 
HETATM 12740 O O    . HOH F 3 .   ? -17.923 51.450  49.599 1.00 25.64 ?  545  HOH B O    1 
HETATM 12741 O O    . HOH F 3 .   ? 9.845   31.815  33.241 1.00 10.82 ?  546  HOH B O    1 
HETATM 12742 O O    . HOH F 3 .   ? -25.018 25.910  42.213 1.00 25.90 ?  547  HOH B O    1 
HETATM 12743 O O    . HOH F 3 .   ? -28.823 33.365  52.158 1.00 18.83 ?  548  HOH B O    1 
HETATM 12744 O O    . HOH F 3 .   ? 5.818   32.507  66.186 1.00 13.15 ?  549  HOH B O    1 
HETATM 12745 O O    . HOH F 3 .   ? -15.792 56.584  33.331 1.00 29.65 ?  550  HOH B O    1 
HETATM 12746 O O    . HOH F 3 .   ? -26.311 33.118  61.956 1.00 13.29 ?  551  HOH B O    1 
HETATM 12747 O O    . HOH F 3 .   ? 0.499   44.299  23.630 1.00 20.92 ?  552  HOH B O    1 
HETATM 12748 O O    . HOH F 3 .   ? -22.716 22.667  57.136 1.00 33.67 ?  553  HOH B O    1 
HETATM 12749 O O    . HOH F 3 .   ? -8.568  30.648  53.035 1.00 11.16 ?  554  HOH B O    1 
HETATM 12750 O O    . HOH F 3 .   ? -2.482  24.986  52.285 1.00 26.30 ?  555  HOH B O    1 
HETATM 12751 O O    . HOH F 3 .   ? 18.008  26.410  26.121 1.00 14.71 ?  556  HOH B O    1 
HETATM 12752 O O    . HOH F 3 .   ? -0.193  43.187  67.818 1.00 19.23 ?  557  HOH B O    1 
HETATM 12753 O O    . HOH F 3 .   ? 18.886  36.398  49.351 1.00 31.03 ?  558  HOH B O    1 
HETATM 12754 O O    . HOH F 3 .   ? 1.768   55.803  42.275 1.00 17.35 ?  559  HOH B O    1 
HETATM 12755 O O    . HOH F 3 .   ? -20.402 29.503  34.917 1.00 16.37 ?  560  HOH B O    1 
HETATM 12756 O O    . HOH F 3 .   ? 1.251   32.077  64.221 1.00 11.14 ?  561  HOH B O    1 
HETATM 12757 O O    . HOH F 3 .   ? 12.072  27.681  59.793 1.00 22.18 ?  562  HOH B O    1 
HETATM 12758 O O    . HOH F 3 .   ? -11.723 37.327  33.891 1.00 9.21  ?  563  HOH B O    1 
HETATM 12759 O O    . HOH F 3 .   ? -1.053  54.671  53.428 1.00 16.02 ?  564  HOH B O    1 
HETATM 12760 O O    . HOH F 3 .   ? 5.004   35.298  28.178 1.00 16.49 ?  565  HOH B O    1 
HETATM 12761 O O    . HOH F 3 .   ? -20.199 57.135  50.047 1.00 32.78 ?  566  HOH B O    1 
HETATM 12762 O O    . HOH F 3 .   ? -15.141 27.703  44.411 1.00 19.42 ?  567  HOH B O    1 
HETATM 12763 O O    . HOH F 3 .   ? 10.461  54.330  45.881 1.00 19.02 ?  568  HOH B O    1 
HETATM 12764 O O    . HOH F 3 .   ? -28.307 18.749  36.574 1.00 17.64 ?  569  HOH B O    1 
HETATM 12765 O O    . HOH F 3 .   ? 13.426  32.947  25.345 1.00 28.12 ?  570  HOH B O    1 
HETATM 12766 O O    . HOH F 3 .   ? -0.404  50.629  57.692 1.00 14.21 ?  571  HOH B O    1 
HETATM 12767 O O    . HOH F 3 .   ? -33.777 29.915  48.810 1.00 21.71 ?  572  HOH B O    1 
HETATM 12768 O O    . HOH F 3 .   ? -0.176  38.252  23.845 1.00 35.91 ?  573  HOH B O    1 
HETATM 12769 O O    . HOH F 3 .   ? 17.094  32.546  50.020 1.00 21.82 ?  574  HOH B O    1 
HETATM 12770 O O    . HOH F 3 .   ? -18.708 21.533  69.176 1.00 27.12 ?  575  HOH B O    1 
HETATM 12771 O O    . HOH F 3 .   ? 3.243   38.881  28.809 1.00 15.93 ?  576  HOH B O    1 
HETATM 12772 O O    . HOH F 3 .   ? 1.301   19.371  68.298 1.00 14.20 ?  577  HOH B O    1 
HETATM 12773 O O    . HOH F 3 .   ? -22.992 59.067  40.438 1.00 28.39 ?  578  HOH B O    1 
HETATM 12774 O O    . HOH F 3 .   ? -26.265 37.477  71.972 1.00 35.42 ?  579  HOH B O    1 
HETATM 12775 O O    . HOH F 3 .   ? -10.808 22.859  55.596 1.00 29.27 ?  580  HOH B O    1 
HETATM 12776 O O    . HOH F 3 .   ? -4.752  60.625  40.428 1.00 28.72 ?  581  HOH B O    1 
HETATM 12777 O O    . HOH F 3 .   ? -9.397  31.836  49.527 1.00 10.36 ?  582  HOH B O    1 
HETATM 12778 O O    . HOH F 3 .   ? -12.883 56.334  51.653 1.00 19.22 ?  583  HOH B O    1 
HETATM 12779 O O    . HOH F 3 .   ? 20.285  40.885  40.810 1.00 20.95 ?  584  HOH B O    1 
HETATM 12780 O O    . HOH F 3 .   ? -8.097  20.807  54.462 1.00 26.72 ?  585  HOH B O    1 
HETATM 12781 O O    . HOH F 3 .   ? -25.040 53.236  38.878 1.00 34.81 ?  586  HOH B O    1 
HETATM 12782 O O    . HOH F 3 .   ? -24.976 47.272  64.880 1.00 32.97 ?  587  HOH B O    1 
HETATM 12783 O O    . HOH F 3 .   ? 1.694   31.271  66.841 1.00 19.79 ?  588  HOH B O    1 
HETATM 12784 O O    . HOH F 3 .   ? -2.987  55.158  55.346 1.00 14.24 ?  589  HOH B O    1 
HETATM 12785 O O    . HOH F 3 .   ? -21.892 17.274  35.560 1.00 23.37 ?  590  HOH B O    1 
HETATM 12786 O O    . HOH F 3 .   ? -5.001  30.760  68.116 1.00 17.64 ?  591  HOH B O    1 
HETATM 12787 O O    . HOH F 3 .   ? -17.620 39.806  51.106 1.00 9.77  ?  592  HOH B O    1 
HETATM 12788 O O    . HOH F 3 .   ? 20.341  38.832  36.705 1.00 21.52 ?  593  HOH B O    1 
HETATM 12789 O O    . HOH F 3 .   ? -7.538  44.700  61.063 1.00 9.65  ?  594  HOH B O    1 
HETATM 12790 O O    . HOH F 3 .   ? 16.444  35.303  31.149 1.00 18.92 ?  595  HOH B O    1 
HETATM 12791 O O    . HOH F 3 .   ? 4.940   47.911  27.503 1.00 15.92 ?  596  HOH B O    1 
HETATM 12792 O O    . HOH F 3 .   ? -9.950  55.037  35.875 1.00 10.93 ?  597  HOH B O    1 
HETATM 12793 O O    . HOH F 3 .   ? 13.062  35.047  54.275 1.00 26.77 ?  598  HOH B O    1 
HETATM 12794 O O    . HOH F 3 .   ? 0.154   26.946  54.194 1.00 10.82 ?  599  HOH B O    1 
HETATM 12795 O O    . HOH F 3 .   ? 15.997  22.918  45.230 1.00 29.54 ?  600  HOH B O    1 
HETATM 12796 O O    . HOH F 3 .   ? -23.189 40.300  73.385 1.00 23.25 ?  601  HOH B O    1 
HETATM 12797 O O    . HOH F 3 .   ? -7.721  34.774  31.677 1.00 14.24 ?  602  HOH B O    1 
HETATM 12798 O O    . HOH F 3 .   ? -17.448 53.877  61.487 1.00 35.49 ?  603  HOH B O    1 
HETATM 12799 O O    . HOH F 3 .   ? -6.137  57.214  46.286 1.00 16.81 ?  604  HOH B O    1 
HETATM 12800 O O    . HOH F 3 .   ? -24.386 27.404  63.080 1.00 22.56 ?  605  HOH B O    1 
HETATM 12801 O O    . HOH F 3 .   ? -20.230 49.863  52.601 1.00 34.74 ?  606  HOH B O    1 
HETATM 12802 O O    . HOH F 3 .   ? 20.488  33.721  35.553 1.00 32.96 ?  607  HOH B O    1 
HETATM 12803 O O    . HOH F 3 .   ? 6.776   55.228  38.210 1.00 33.28 ?  608  HOH B O    1 
HETATM 12804 O O    . HOH F 3 .   ? 18.830  30.217  36.439 1.00 25.26 ?  609  HOH B O    1 
HETATM 12805 O O    . HOH F 3 .   ? 12.923  48.938  32.342 1.00 19.80 ?  610  HOH B O    1 
HETATM 12806 O O    . HOH F 3 .   ? -2.346  34.154  52.661 1.00 8.29  ?  611  HOH B O    1 
HETATM 12807 O O    . HOH F 3 .   ? 9.024   37.032  24.262 1.00 24.33 ?  612  HOH B O    1 
HETATM 12808 O O    . HOH F 3 .   ? 1.885   57.305  47.213 1.00 12.73 ?  613  HOH B O    1 
HETATM 12809 O O    . HOH F 3 .   ? 3.569   49.775  53.689 1.00 13.80 ?  614  HOH B O    1 
HETATM 12810 O O    . HOH F 3 .   ? -1.800  23.878  30.109 1.00 14.39 ?  615  HOH B O    1 
HETATM 12811 O O    . HOH F 3 .   ? -22.395 33.993  38.837 1.00 18.53 ?  616  HOH B O    1 
HETATM 12812 O O    . HOH F 3 .   ? -9.860  24.911  52.662 1.00 29.26 ?  617  HOH B O    1 
HETATM 12813 O O    . HOH F 3 .   ? -24.850 38.511  75.712 1.00 38.95 ?  618  HOH B O    1 
HETATM 12814 O O    . HOH F 3 .   ? 17.459  43.533  49.090 1.00 21.25 ?  619  HOH B O    1 
HETATM 12815 O O    . HOH F 3 .   ? -28.847 45.572  60.981 1.00 26.93 ?  620  HOH B O    1 
HETATM 12816 O O    . HOH F 3 .   ? -4.145  29.270  59.140 1.00 9.70  ?  621  HOH B O    1 
HETATM 12817 O O    . HOH F 3 .   ? -32.575 34.706  60.882 1.00 38.53 ?  622  HOH B O    1 
HETATM 12818 O O    . HOH F 3 .   ? -15.846 31.876  40.485 1.00 10.98 ?  623  HOH B O    1 
HETATM 12819 O O    . HOH F 3 .   ? 9.102   23.400  40.965 1.00 20.48 ?  624  HOH B O    1 
HETATM 12820 O O    . HOH F 3 .   ? 13.172  27.844  63.529 1.00 14.62 ?  625  HOH B O    1 
HETATM 12821 O O    . HOH F 3 .   ? -6.869  47.477  63.733 1.00 13.72 ?  626  HOH B O    1 
HETATM 12822 O O    . HOH F 3 .   ? -27.736 16.231  37.086 1.00 19.18 ?  627  HOH B O    1 
HETATM 12823 O O    . HOH F 3 .   ? -9.587  38.598  69.095 1.00 16.31 ?  628  HOH B O    1 
HETATM 12824 O O    . HOH F 3 .   ? -6.452  55.016  49.707 1.00 14.91 ?  629  HOH B O    1 
HETATM 12825 O O    . HOH F 3 .   ? -24.196 48.512  57.608 1.00 32.86 ?  630  HOH B O    1 
HETATM 12826 O O    . HOH F 3 .   ? -10.560 28.691  52.256 1.00 11.64 ?  631  HOH B O    1 
HETATM 12827 O O    . HOH F 3 .   ? -18.026 14.379  28.768 1.00 8.65  ?  632  HOH B O    1 
HETATM 12828 O O    . HOH F 3 .   ? -29.049 39.391  45.498 1.00 39.93 ?  633  HOH B O    1 
HETATM 12829 O O    . HOH F 3 .   ? -21.395 44.934  50.201 1.00 19.30 ?  634  HOH B O    1 
HETATM 12830 O O    . HOH F 3 .   ? 11.408  24.076  32.050 1.00 24.96 ?  635  HOH B O    1 
HETATM 12831 O O    . HOH F 3 .   ? -1.446  60.714  40.987 1.00 21.61 ?  636  HOH B O    1 
HETATM 12832 O O    . HOH F 3 .   ? 1.365   52.615  51.880 1.00 14.05 ?  637  HOH B O    1 
HETATM 12833 O O    . HOH F 3 .   ? 5.839   29.197  63.100 1.00 12.02 ?  638  HOH B O    1 
HETATM 12834 O O    . HOH F 3 .   ? 16.487  29.152  25.081 1.00 32.68 ?  639  HOH B O    1 
HETATM 12835 O O    . HOH F 3 .   ? -8.566  36.802  75.784 1.00 29.58 ?  640  HOH B O    1 
HETATM 12836 O O    . HOH F 3 .   ? -25.325 39.973  36.244 1.00 18.48 ?  641  HOH B O    1 
HETATM 12837 O O    . HOH F 3 .   ? -28.185 34.456  60.417 1.00 16.23 ?  642  HOH B O    1 
HETATM 12838 O O    . HOH F 3 .   ? 0.250   28.316  25.402 1.00 30.47 ?  643  HOH B O    1 
HETATM 12839 O O    . HOH F 3 .   ? -12.671 21.218  70.888 1.00 18.04 ?  644  HOH B O    1 
HETATM 12840 O O    . HOH F 3 .   ? -16.732 42.622  77.702 1.00 30.00 ?  645  HOH B O    1 
HETATM 12841 O O    . HOH F 3 .   ? -35.486 24.939  49.524 1.00 31.73 ?  646  HOH B O    1 
HETATM 12842 O O    . HOH F 3 .   ? -9.811  57.364  44.262 1.00 29.46 ?  647  HOH B O    1 
HETATM 12843 O O    . HOH F 3 .   ? -2.872  59.958  47.847 1.00 34.53 ?  648  HOH B O    1 
HETATM 12844 O O    . HOH F 3 .   ? -28.169 41.300  65.716 1.00 18.17 ?  649  HOH B O    1 
HETATM 12845 O O    . HOH F 3 .   ? -10.821 54.983  57.750 1.00 24.73 ?  650  HOH B O    1 
HETATM 12846 O O    . HOH F 3 .   ? -31.707 23.187  43.891 1.00 21.19 ?  651  HOH B O    1 
HETATM 12847 O O    . HOH F 3 .   ? 5.355   23.073  34.574 1.00 14.76 ?  652  HOH B O    1 
HETATM 12848 O O    . HOH F 3 .   ? -22.966 40.037  32.123 1.00 25.50 ?  653  HOH B O    1 
HETATM 12849 O O    . HOH F 3 .   ? -21.349 36.909  48.263 1.00 23.74 ?  654  HOH B O    1 
HETATM 12850 O O    . HOH F 3 .   ? -4.760  56.907  48.698 1.00 18.47 ?  655  HOH B O    1 
HETATM 12851 O O    . HOH F 3 .   ? 11.363  32.053  54.358 1.00 40.22 ?  656  HOH B O    1 
HETATM 12852 O O    . HOH F 3 .   ? 11.076  51.556  52.111 1.00 21.23 ?  657  HOH B O    1 
HETATM 12853 O O    . HOH F 3 .   ? -19.821 33.629  73.226 1.00 20.83 ?  658  HOH B O    1 
HETATM 12854 O O    . HOH F 3 .   ? -8.343  40.108  61.699 1.00 24.76 ?  659  HOH B O    1 
HETATM 12855 O O    . HOH F 3 .   ? -24.052 43.333  74.559 1.00 34.45 ?  660  HOH B O    1 
HETATM 12856 O O    . HOH F 3 .   ? -26.570 45.925  42.886 1.00 18.65 ?  661  HOH B O    1 
HETATM 12857 O O    . HOH F 3 .   ? -21.322 60.666  41.298 1.00 25.00 ?  662  HOH B O    1 
HETATM 12858 O O    . HOH F 3 .   ? -28.432 33.692  54.913 1.00 15.60 ?  663  HOH B O    1 
HETATM 12859 O O    . HOH F 3 .   ? -0.205  57.285  43.572 1.00 14.45 ?  664  HOH B O    1 
HETATM 12860 O O    . HOH F 3 .   ? -3.366  51.047  29.092 1.00 35.21 ?  665  HOH B O    1 
HETATM 12861 O O    . HOH F 3 .   ? 10.840  33.767  58.202 1.00 21.12 ?  666  HOH B O    1 
HETATM 12862 O O    . HOH F 3 .   ? -6.661  44.486  37.655 1.00 8.72  ?  667  HOH B O    1 
HETATM 12863 O O    . HOH F 3 .   ? 0.035   39.712  30.081 1.00 9.60  ?  668  HOH B O    1 
HETATM 12864 O O    . HOH F 3 .   ? 13.620  41.946  54.711 1.00 32.65 ?  669  HOH B O    1 
HETATM 12865 O O    . HOH F 3 .   ? -0.467  59.445  53.610 1.00 29.68 ?  670  HOH B O    1 
HETATM 12866 O O    . HOH F 3 .   ? 11.765  34.341  26.773 1.00 21.31 ?  671  HOH B O    1 
HETATM 12867 O O    . HOH F 3 .   ? 11.192  25.136  28.791 1.00 32.55 ?  672  HOH B O    1 
HETATM 12868 O O    . HOH F 3 .   ? 9.910   25.031  61.197 1.00 13.24 ?  673  HOH B O    1 
HETATM 12869 O O    . HOH F 3 .   ? -22.966 33.711  35.042 1.00 27.23 ?  674  HOH B O    1 
HETATM 12870 O O    . HOH F 3 .   ? 2.001   35.087  48.156 1.00 8.77  ?  675  HOH B O    1 
HETATM 12871 O O    . HOH F 3 .   ? -0.509  29.104  42.824 1.00 9.33  ?  676  HOH B O    1 
HETATM 12872 O O    . HOH F 3 .   ? 10.496  26.273  26.668 1.00 24.68 ?  677  HOH B O    1 
HETATM 12873 O O    . HOH F 3 .   ? 8.896   24.836  36.529 1.00 32.55 ?  678  HOH B O    1 
HETATM 12874 O O    . HOH F 3 .   ? -6.380  58.569  50.554 1.00 26.51 ?  679  HOH B O    1 
HETATM 12875 O O    . HOH F 3 .   ? -3.326  32.362  55.452 1.00 9.65  ?  680  HOH B O    1 
HETATM 12876 O O    . HOH F 3 .   ? -28.398 45.609  57.268 1.00 27.43 ?  681  HOH B O    1 
HETATM 12877 O O    . HOH F 3 .   ? 14.957  49.381  47.551 1.00 29.58 ?  682  HOH B O    1 
HETATM 12878 O O    . HOH F 3 .   ? -17.400 27.977  41.171 1.00 15.95 ?  683  HOH B O    1 
HETATM 12879 O O    . HOH F 3 .   ? -16.641 36.260  32.567 1.00 10.71 ?  684  HOH B O    1 
HETATM 12880 O O    . HOH F 3 .   ? -7.320  31.322  77.850 1.00 35.99 ?  685  HOH B O    1 
HETATM 12881 O O    . HOH F 3 .   ? -1.220  41.821  69.974 1.00 31.45 ?  686  HOH B O    1 
HETATM 12882 O O    . HOH F 3 .   ? -19.492 52.910  62.488 1.00 26.78 ?  687  HOH B O    1 
HETATM 12883 O O    . HOH F 3 .   ? -5.599  32.815  69.646 1.00 19.36 ?  688  HOH B O    1 
HETATM 12884 O O    . HOH F 3 .   ? 23.250  30.356  46.809 1.00 20.16 ?  689  HOH B O    1 
HETATM 12885 O O    . HOH F 3 .   ? 15.671  49.636  43.853 1.00 27.17 ?  690  HOH B O    1 
HETATM 12886 O O    . HOH F 3 .   ? 2.204   60.008  46.469 1.00 30.86 ?  691  HOH B O    1 
HETATM 12887 O O    . HOH F 3 .   ? -25.588 36.148  40.555 1.00 33.28 ?  692  HOH B O    1 
HETATM 12888 O O    . HOH F 3 .   ? -4.221  24.786  70.774 1.00 18.51 ?  693  HOH B O    1 
HETATM 12889 O O    . HOH F 3 .   ? -6.463  50.257  64.361 1.00 32.66 ?  694  HOH B O    1 
HETATM 12890 O O    . HOH F 3 .   ? -21.920 46.788  31.027 1.00 30.65 ?  695  HOH B O    1 
HETATM 12891 O O    . HOH F 3 .   ? -8.339  54.352  63.040 1.00 27.21 ?  696  HOH B O    1 
HETATM 12892 O O    . HOH F 3 .   ? -1.222  16.961  67.100 1.00 28.05 ?  697  HOH B O    1 
HETATM 12893 O O    . HOH F 3 .   ? -9.772  41.911  75.722 1.00 33.15 ?  698  HOH B O    1 
HETATM 12894 O O    . HOH F 3 .   ? -19.546 25.825  37.286 1.00 27.50 ?  699  HOH B O    1 
HETATM 12895 O O    . HOH F 3 .   ? -31.610 23.818  39.957 1.00 29.72 ?  700  HOH B O    1 
HETATM 12896 O O    . HOH F 3 .   ? 17.210  23.114  40.583 1.00 31.16 ?  701  HOH B O    1 
HETATM 12897 O O    . HOH F 3 .   ? -10.041 31.308  79.819 1.00 30.84 ?  702  HOH B O    1 
HETATM 12898 O O    . HOH F 3 .   ? -27.527 24.693  50.076 1.00 29.55 ?  703  HOH B O    1 
HETATM 12899 O O    . HOH F 3 .   ? -18.427 25.355  43.932 1.00 21.73 ?  704  HOH B O    1 
HETATM 12900 O O    . HOH F 3 .   ? -25.566 30.021  64.740 1.00 18.54 ?  705  HOH B O    1 
HETATM 12901 O O    . HOH F 3 .   ? 24.523  28.304  33.326 1.00 27.50 ?  706  HOH B O    1 
HETATM 12902 O O    . HOH F 3 .   ? 18.492  43.416  42.741 1.00 21.47 ?  707  HOH B O    1 
HETATM 12903 O O    . HOH F 3 .   ? 8.614   43.241  58.210 1.00 21.08 ?  708  HOH B O    1 
HETATM 12904 O O    . HOH F 3 .   ? -5.083  17.965  67.832 1.00 32.99 ?  709  HOH B O    1 
HETATM 12905 O O    . HOH F 3 .   ? 14.460  47.231  43.087 1.00 20.11 ?  710  HOH B O    1 
HETATM 12906 O O    . HOH F 3 .   ? -16.385 25.533  37.576 1.00 25.21 ?  711  HOH B O    1 
HETATM 12907 O O    . HOH F 3 .   ? -11.321 20.312  56.855 1.00 26.45 ?  712  HOH B O    1 
HETATM 12908 O O    . HOH F 3 .   ? -19.687 37.795  29.507 1.00 28.40 ?  713  HOH B O    1 
HETATM 12909 O O    . HOH F 3 .   ? 20.485  43.700  36.530 1.00 22.69 ?  714  HOH B O    1 
HETATM 12910 O O    . HOH F 3 .   ? -1.166  51.706  29.988 1.00 32.67 ?  715  HOH B O    1 
HETATM 12911 O O    . HOH F 3 .   ? -9.092  57.163  57.392 1.00 26.86 ?  716  HOH B O    1 
HETATM 12912 O O    . HOH F 3 .   ? -18.843 15.712  45.817 1.00 44.88 ?  717  HOH B O    1 
HETATM 12913 O O    . HOH F 3 .   ? -20.953 54.187  37.349 1.00 15.04 ?  718  HOH B O    1 
HETATM 12914 O O    . HOH F 3 .   ? -7.886  29.492  50.030 1.00 12.13 ?  719  HOH B O    1 
HETATM 12915 O O    . HOH F 3 .   ? 0.085   41.092  37.575 1.00 7.93  ?  720  HOH B O    1 
HETATM 12916 O O    . HOH F 3 .   ? 11.616  47.717  26.140 1.00 28.79 ?  721  HOH B O    1 
HETATM 12917 O O    . HOH F 3 .   ? -19.127 22.291  32.033 1.00 15.12 ?  722  HOH B O    1 
HETATM 12918 O O    . HOH F 3 .   ? -21.515 25.605  62.255 1.00 16.00 ?  723  HOH B O    1 
HETATM 12919 O O    . HOH F 3 .   ? 4.676   27.738  65.099 1.00 14.14 ?  724  HOH B O    1 
HETATM 12920 O O    . HOH F 3 .   ? -16.513 46.968  33.930 1.00 12.53 ?  725  HOH B O    1 
HETATM 12921 O O    . HOH F 3 .   ? -23.480 23.378  32.900 1.00 16.76 ?  726  HOH B O    1 
HETATM 12922 O O    . HOH F 3 .   ? -28.917 38.945  48.309 1.00 21.45 ?  727  HOH B O    1 
HETATM 12923 O O    . HOH F 3 .   ? 1.152   27.880  51.846 1.00 9.94  ?  728  HOH B O    1 
HETATM 12924 O O    . HOH F 3 .   ? -8.189  37.506  26.169 1.00 33.54 ?  729  HOH B O    1 
HETATM 12925 O O    . HOH F 3 .   ? 7.646   23.061  53.930 1.00 20.11 ?  730  HOH B O    1 
HETATM 12926 O O    . HOH F 3 .   ? 4.056   49.372  56.521 1.00 21.20 ?  731  HOH B O    1 
HETATM 12927 O O    . HOH F 3 .   ? 19.956  43.746  39.548 1.00 33.63 ?  732  HOH B O    1 
HETATM 12928 O O    . HOH F 3 .   ? -17.152 41.604  24.246 1.00 28.31 ?  733  HOH B O    1 
HETATM 12929 O O    . HOH F 3 .   ? 12.378  25.786  51.057 1.00 21.36 ?  734  HOH B O    1 
HETATM 12930 O O    . HOH F 3 .   ? -15.936 53.780  33.067 1.00 18.51 ?  735  HOH B O    1 
HETATM 12931 O O    . HOH F 3 .   ? -30.469 36.697  71.462 1.00 40.68 ?  736  HOH B O    1 
HETATM 12932 O O    . HOH F 3 .   ? -16.905 25.811  52.908 1.00 29.47 ?  737  HOH B O    1 
HETATM 12933 O O    . HOH F 3 .   ? -7.156  42.773  22.801 1.00 35.60 ?  738  HOH B O    1 
HETATM 12934 O O    . HOH F 3 .   ? 2.467   34.574  64.065 1.00 11.59 ?  739  HOH B O    1 
HETATM 12935 O O    . HOH F 3 .   ? -15.114 19.105  70.539 1.00 22.06 ?  740  HOH B O    1 
HETATM 12936 O O    . HOH F 3 .   ? 19.613  40.019  43.286 1.00 20.17 ?  741  HOH B O    1 
HETATM 12937 O O    . HOH F 3 .   ? -18.823 18.018  63.423 1.00 27.83 ?  742  HOH B O    1 
HETATM 12938 O O    . HOH F 3 .   ? -25.649 47.474  32.521 1.00 21.17 ?  743  HOH B O    1 
HETATM 12939 O O    . HOH F 3 .   ? -22.630 49.590  51.633 1.00 40.89 ?  744  HOH B O    1 
HETATM 12940 O O    . HOH F 3 .   ? -2.204  39.215  69.868 1.00 34.76 ?  745  HOH B O    1 
HETATM 12941 O O    . HOH F 3 .   ? -13.816 29.549  74.783 1.00 30.20 ?  746  HOH B O    1 
HETATM 12942 O O    . HOH F 3 .   ? -17.931 51.095  63.996 1.00 18.60 ?  747  HOH B O    1 
HETATM 12943 O O    . HOH F 3 .   ? -21.459 22.043  41.315 1.00 32.70 ?  748  HOH B O    1 
HETATM 12944 O O    . HOH F 3 .   ? 5.419   37.113  66.698 1.00 20.76 ?  749  HOH B O    1 
HETATM 12945 O O    . HOH F 3 .   ? 6.468   37.870  20.496 1.00 34.96 ?  750  HOH B O    1 
HETATM 12946 O O    . HOH F 3 .   ? -1.507  36.640  68.720 1.00 23.29 ?  751  HOH B O    1 
HETATM 12947 O O    . HOH F 3 .   ? -22.966 42.678  50.144 1.00 17.85 ?  752  HOH B O    1 
HETATM 12948 O O    . HOH F 3 .   ? 6.429   50.145  33.237 1.00 14.85 ?  753  HOH B O    1 
HETATM 12949 O O    . HOH F 3 .   ? -3.726  58.649  60.903 1.00 28.14 ?  754  HOH B O    1 
HETATM 12950 O O    . HOH F 3 .   ? -28.592 27.248  59.745 1.00 30.46 ?  755  HOH B O    1 
HETATM 12951 O O    . HOH F 3 .   ? -22.125 28.717  37.268 1.00 28.57 ?  756  HOH B O    1 
HETATM 12952 O O    . HOH F 3 .   ? -12.581 48.483  67.306 1.00 25.56 ?  757  HOH B O    1 
HETATM 12953 O O    . HOH F 3 .   ? -3.653  32.368  71.437 1.00 25.04 ?  758  HOH B O    1 
HETATM 12954 O O    . HOH F 3 .   ? -23.253 55.033  47.011 1.00 29.14 ?  759  HOH B O    1 
HETATM 12955 O O    . HOH F 3 .   ? -10.691 32.063  42.129 1.00 14.43 ?  760  HOH B O    1 
HETATM 12956 O O    . HOH F 3 .   ? -7.394  33.526  75.308 1.00 25.39 ?  761  HOH B O    1 
HETATM 12957 O O    . HOH F 3 .   ? 5.742   47.266  49.775 1.00 17.88 ?  762  HOH B O    1 
HETATM 12958 O O    . HOH F 3 .   ? -8.049  34.081  70.851 1.00 21.30 ?  763  HOH B O    1 
HETATM 12959 O O    . HOH F 3 .   ? 17.493  35.096  28.475 1.00 32.68 ?  764  HOH B O    1 
HETATM 12960 O O    . HOH F 3 .   ? 1.826   48.656  32.584 1.00 12.89 ?  765  HOH B O    1 
HETATM 12961 O O    . HOH F 3 .   ? -2.442  30.152  56.982 1.00 10.72 ?  766  HOH B O    1 
HETATM 12962 O O    . HOH F 3 .   ? -25.462 25.346  34.355 1.00 31.03 ?  767  HOH B O    1 
HETATM 12963 O O    . HOH F 3 .   ? -19.129 45.883  54.848 1.00 14.77 ?  768  HOH B O    1 
HETATM 12964 O O    . HOH F 3 .   ? -18.394 60.089  43.143 1.00 27.42 ?  769  HOH B O    1 
HETATM 12965 O O    . HOH F 3 .   ? -14.534 28.562  47.082 1.00 16.22 ?  770  HOH B O    1 
HETATM 12966 O O    . HOH F 3 .   ? -3.033  57.827  43.894 1.00 11.97 ?  771  HOH B O    1 
HETATM 12967 O O    . HOH F 3 .   ? -30.015 42.337  63.841 1.00 28.65 ?  772  HOH B O    1 
HETATM 12968 O O    . HOH F 3 .   ? -15.620 36.463  27.396 1.00 21.38 ?  773  HOH B O    1 
HETATM 12969 O O    . HOH F 3 .   ? -20.637 46.170  52.518 1.00 19.54 ?  774  HOH B O    1 
HETATM 12970 O O    . HOH F 3 .   ? -22.706 24.446  43.091 1.00 31.51 ?  775  HOH B O    1 
HETATM 12971 O O    . HOH F 3 .   ? -11.071 22.009  72.891 1.00 17.21 ?  776  HOH B O    1 
HETATM 12972 O O    . HOH F 3 .   ? -0.429  26.869  36.561 1.00 12.80 ?  777  HOH B O    1 
HETATM 12973 O O    . HOH F 3 .   ? -7.140  17.439  60.945 1.00 22.70 ?  778  HOH B O    1 
HETATM 12974 O O    . HOH F 3 .   ? 20.633  36.290  38.988 1.00 19.94 ?  779  HOH B O    1 
HETATM 12975 O O    . HOH F 3 .   ? 4.177   56.542  43.220 1.00 29.04 ?  780  HOH B O    1 
HETATM 12976 O O    . HOH F 3 .   ? -27.888 30.926  68.989 1.00 27.79 ?  781  HOH B O    1 
HETATM 12977 O O    . HOH F 3 .   ? -18.891 20.253  60.719 1.00 39.66 ?  782  HOH B O    1 
HETATM 12978 O O    . HOH F 3 .   ? 12.807  27.876  26.665 1.00 17.68 ?  783  HOH B O    1 
HETATM 12979 O O    . HOH F 3 .   ? -6.381  40.873  26.580 1.00 23.63 ?  784  HOH B O    1 
HETATM 12980 O O    . HOH F 3 .   ? -5.363  38.360  71.246 1.00 31.74 ?  785  HOH B O    1 
HETATM 12981 O O    . HOH F 3 .   ? -8.202  19.056  63.486 1.00 18.83 ?  786  HOH B O    1 
HETATM 12982 O O    . HOH F 3 .   ? -21.329 24.740  35.334 1.00 27.34 ?  787  HOH B O    1 
HETATM 12983 O O    . HOH F 3 .   ? -6.250  58.301  43.483 1.00 13.33 ?  788  HOH B O    1 
HETATM 12984 O O    . HOH F 3 .   ? -11.875 30.534  35.462 1.00 22.38 ?  789  HOH B O    1 
HETATM 12985 O O    . HOH F 3 .   ? -32.919 23.971  55.198 1.00 31.91 ?  790  HOH B O    1 
HETATM 12986 O O    . HOH F 3 .   ? -8.577  40.833  25.041 1.00 24.25 ?  791  HOH B O    1 
HETATM 12987 O O    . HOH F 3 .   ? -1.667  47.064  69.714 1.00 39.00 ?  792  HOH B O    1 
HETATM 12988 O O    . HOH F 3 .   ? 19.002  45.280  33.633 1.00 19.81 ?  793  HOH B O    1 
HETATM 12989 O O    . HOH F 3 .   ? 9.293   24.466  34.211 1.00 20.61 ?  794  HOH B O    1 
HETATM 12990 O O    . HOH F 3 .   ? 9.638   46.782  18.770 1.00 33.33 ?  795  HOH B O    1 
HETATM 12991 O O    . HOH F 3 .   ? -19.243 19.604  39.580 1.00 38.48 ?  796  HOH B O    1 
HETATM 12992 O O    . HOH F 3 .   ? -12.155 32.178  39.672 1.00 25.55 ?  797  HOH B O    1 
HETATM 12993 O O    . HOH F 3 .   ? -14.498 29.908  39.171 1.00 16.85 ?  798  HOH B O    1 
HETATM 12994 O O    . HOH F 3 .   ? -1.551  21.666  34.856 1.00 20.67 ?  799  HOH B O    1 
HETATM 12995 O O    . HOH F 3 .   ? -0.440  17.514  55.520 1.00 19.15 ?  800  HOH B O    1 
HETATM 12996 O O    . HOH F 3 .   ? -27.786 46.285  35.373 1.00 17.83 ?  801  HOH B O    1 
HETATM 12997 O O    . HOH F 3 .   ? -20.035 58.735  46.767 1.00 29.84 ?  802  HOH B O    1 
HETATM 12998 O O    . HOH F 3 .   ? -8.407  35.293  28.312 1.00 23.76 ?  803  HOH B O    1 
HETATM 12999 O O    . HOH F 3 .   ? -15.135 38.710  74.292 1.00 25.64 ?  804  HOH B O    1 
HETATM 13000 O O    . HOH F 3 .   ? 4.140   57.922  34.210 1.00 40.10 ?  805  HOH B O    1 
HETATM 13001 O O    . HOH F 3 .   ? 5.123   25.568  40.624 1.00 18.35 ?  806  HOH B O    1 
HETATM 13002 O O    . HOH F 3 .   ? -14.406 18.216  62.084 1.00 35.16 ?  807  HOH B O    1 
HETATM 13003 O O    . HOH F 3 .   ? -12.814 40.810  22.686 1.00 36.82 ?  808  HOH B O    1 
HETATM 13004 O O    . HOH F 3 .   ? 11.649  49.212  53.546 1.00 33.70 ?  809  HOH B O    1 
HETATM 13005 O O    . HOH F 3 .   ? -24.837 41.921  77.471 1.00 34.16 ?  810  HOH B O    1 
HETATM 13006 O O    . HOH F 3 .   ? 5.478   58.911  48.187 1.00 33.27 ?  811  HOH B O    1 
HETATM 13007 O O    . HOH F 3 .   ? -10.531 35.505  27.332 1.00 30.28 ?  812  HOH B O    1 
HETATM 13008 O O    . HOH F 3 .   ? -4.370  42.499  26.396 1.00 26.24 ?  813  HOH B O    1 
HETATM 13009 O O    . HOH F 3 .   ? -1.139  32.902  31.329 1.00 15.05 ?  814  HOH B O    1 
HETATM 13010 O O    . HOH F 3 .   ? -16.217 35.874  75.107 1.00 27.46 ?  815  HOH B O    1 
HETATM 13011 O O    . HOH F 3 .   ? -29.136 32.818  58.331 1.00 21.48 ?  816  HOH B O    1 
HETATM 13012 O O    . HOH F 3 .   ? -16.851 48.322  57.013 1.00 14.71 ?  817  HOH B O    1 
HETATM 13013 O O    . HOH F 3 .   ? -29.307 34.072  66.834 1.00 20.56 ?  818  HOH B O    1 
HETATM 13014 O O    . HOH F 3 .   ? 0.276   27.596  68.272 1.00 17.95 ?  819  HOH B O    1 
HETATM 13015 O O    . HOH F 3 .   ? 0.968   53.992  55.129 1.00 19.55 ?  820  HOH B O    1 
HETATM 13016 O O    . HOH F 3 .   ? -23.249 45.140  53.826 1.00 29.69 ?  821  HOH B O    1 
HETATM 13017 O O    . HOH F 3 .   ? -19.807 37.672  45.510 1.00 20.68 ?  822  HOH B O    1 
HETATM 13018 O O    . HOH F 3 .   ? -17.132 56.166  34.541 1.00 8.53  ?  823  HOH B O    1 
HETATM 13019 O O    . HOH F 3 .   ? 14.225  32.832  59.692 1.00 34.74 ?  824  HOH B O    1 
HETATM 13020 O O    . HOH F 3 .   ? 20.990  24.415  42.615 1.00 19.93 ?  825  HOH B O    1 
HETATM 13021 O O    . HOH F 3 .   ? -28.372 47.858  41.782 1.00 23.99 ?  826  HOH B O    1 
HETATM 13022 O O    . HOH F 3 .   ? -3.034  22.288  51.619 1.00 34.19 ?  827  HOH B O    1 
HETATM 13023 O O    . HOH F 3 .   ? -29.025 23.102  48.081 1.00 28.93 ?  828  HOH B O    1 
HETATM 13024 O O    . HOH F 3 .   ? 19.984  35.598  31.910 1.00 36.66 ?  829  HOH B O    1 
HETATM 13025 O O    . HOH F 3 .   ? -22.581 52.398  47.674 1.00 20.59 ?  830  HOH B O    1 
HETATM 13026 O O    . HOH F 3 .   ? -13.975 25.426  49.538 1.00 29.41 ?  831  HOH B O    1 
HETATM 13027 O O    . HOH F 3 .   ? -31.627 36.040  67.130 1.00 38.44 ?  832  HOH B O    1 
HETATM 13028 O O    . HOH F 3 .   ? -12.034 43.939  23.800 1.00 23.08 ?  833  HOH B O    1 
HETATM 13029 O O    . HOH F 3 .   ? -25.930 30.110  72.437 1.00 33.72 ?  834  HOH B O    1 
HETATM 13030 O O    . HOH F 3 .   ? -30.703 38.436  50.231 1.00 34.45 ?  835  HOH B O    1 
HETATM 13031 O O    . HOH F 3 .   ? 13.684  29.832  58.256 1.00 34.70 ?  836  HOH B O    1 
HETATM 13032 O O    . HOH F 3 .   ? -14.041 31.532  79.262 1.00 29.81 ?  837  HOH B O    1 
HETATM 13033 O O    . HOH F 3 .   ? 1.514   36.691  29.578 1.00 21.99 ?  838  HOH B O    1 
HETATM 13034 O O    . HOH F 3 .   ? -33.465 36.843  53.071 1.00 42.26 ?  839  HOH B O    1 
HETATM 13035 O O    . HOH F 3 .   ? -19.904 58.868  44.468 1.00 31.74 ?  840  HOH B O    1 
HETATM 13036 O O    . HOH F 3 .   ? -1.348  25.470  67.168 1.00 17.02 ?  841  HOH B O    1 
HETATM 13037 O O    . HOH F 3 .   ? -15.209 28.836  76.496 1.00 36.06 ?  842  HOH B O    1 
HETATM 13038 O O    . HOH F 3 .   ? -11.603 43.520  71.589 1.00 20.86 ?  843  HOH B O    1 
HETATM 13039 O O    . HOH F 3 .   ? -7.213  37.924  70.553 1.00 29.87 ?  844  HOH B O    1 
HETATM 13040 O O    . HOH F 3 .   ? -21.698 51.530  50.402 1.00 37.86 ?  845  HOH B O    1 
HETATM 13041 O O    . HOH F 3 .   ? -30.862 39.264  57.992 1.00 28.18 ?  846  HOH B O    1 
HETATM 13042 O O    . HOH F 3 .   ? -3.777  19.897  71.396 1.00 20.13 ?  847  HOH B O    1 
HETATM 13043 O O    . HOH F 3 .   ? -19.338 54.329  51.819 1.00 33.87 ?  848  HOH B O    1 
HETATM 13044 O O    . HOH F 3 .   ? -8.139  18.117  71.229 1.00 37.01 ?  849  HOH B O    1 
HETATM 13045 O O    . HOH F 3 .   ? 17.904  33.311  24.661 1.00 32.31 ?  850  HOH B O    1 
HETATM 13046 O O    . HOH F 3 .   ? -35.575 34.101  50.616 1.00 31.34 ?  851  HOH B O    1 
HETATM 13047 O O    . HOH F 3 .   ? -11.138 58.640  45.537 1.00 33.41 ?  852  HOH B O    1 
HETATM 13048 O O    . HOH F 3 .   ? -20.994 17.558  37.588 1.00 23.38 ?  853  HOH B O    1 
HETATM 13049 O O    . HOH F 3 .   ? -25.387 43.414  48.622 1.00 27.78 ?  854  HOH B O    1 
HETATM 13050 O O    . HOH F 3 .   ? -21.172 16.387  46.787 1.00 42.85 ?  855  HOH B O    1 
HETATM 13051 O O    . HOH F 3 .   ? -14.443 43.998  22.324 1.00 31.22 ?  856  HOH B O    1 
HETATM 13052 O O    . HOH F 3 .   ? 6.337   37.098  23.678 1.00 30.53 ?  857  HOH B O    1 
HETATM 13053 O O    . HOH F 3 .   ? -23.579 49.455  30.986 1.00 38.98 ?  858  HOH B O    1 
HETATM 13054 O O    . HOH F 3 .   ? -3.602  51.658  31.056 1.00 34.85 ?  859  HOH B O    1 
HETATM 13055 O O    . HOH F 3 .   ? 18.254  45.043  44.248 1.00 36.94 ?  860  HOH B O    1 
HETATM 13056 O O    . HOH F 3 .   ? 20.173  34.365  25.992 1.00 27.70 ?  861  HOH B O    1 
HETATM 13057 O O    . HOH F 3 .   ? 4.633   62.176  50.802 1.00 40.28 ?  862  HOH B O    1 
HETATM 13058 O O    . HOH F 3 .   ? 8.363   58.791  47.901 1.00 36.97 ?  863  HOH B O    1 
HETATM 13059 O O    . HOH F 3 .   ? 18.004  27.298  48.861 1.00 23.40 ?  864  HOH B O    1 
HETATM 13060 O O    . HOH F 3 .   ? -22.871 31.448  38.303 1.00 29.55 ?  865  HOH B O    1 
HETATM 13061 O O    . HOH F 3 .   ? -11.276 46.469  22.836 1.00 24.22 ?  866  HOH B O    1 
HETATM 13062 O O    . HOH F 3 .   ? -11.866 26.672  80.174 1.00 37.40 ?  867  HOH B O    1 
HETATM 13063 O O    . HOH F 3 .   ? 23.085  33.523  45.863 1.00 33.71 ?  868  HOH B O    1 
HETATM 13064 O O    . HOH F 3 .   ? 8.931   39.390  19.130 1.00 40.09 ?  869  HOH B O    1 
HETATM 13065 O O    . HOH F 3 .   ? -5.251  17.704  70.192 1.00 31.46 ?  870  HOH B O    1 
HETATM 13066 O O    . HOH F 3 .   ? -2.564  59.120  36.237 1.00 33.12 ?  871  HOH B O    1 
HETATM 13067 O O    . HOH F 3 .   ? 17.109  19.714  28.059 1.00 26.57 ?  872  HOH B O    1 
HETATM 13068 O O    . HOH F 3 .   ? -16.371 18.202  60.648 1.00 37.21 ?  873  HOH B O    1 
HETATM 13069 O O    . HOH F 3 .   ? 4.166   24.520  59.735 1.00 12.44 ?  874  HOH B O    1 
HETATM 13070 O O    . HOH F 3 .   ? 2.477   54.219  65.761 1.00 48.37 ?  875  HOH B O    1 
HETATM 13071 O O    . HOH F 3 .   ? -9.203  22.458  52.845 1.00 35.56 ?  876  HOH B O    1 
HETATM 13072 O O    . HOH F 3 .   ? 16.429  50.338  46.239 1.00 38.58 ?  877  HOH B O    1 
HETATM 13073 O O    . HOH F 3 .   ? 16.030  45.666  50.416 1.00 27.16 ?  878  HOH B O    1 
HETATM 13074 O O    . HOH F 3 .   ? 6.083   60.872  50.042 1.00 43.49 ?  879  HOH B O    1 
HETATM 13075 O O    . HOH F 3 .   ? -3.669  36.904  25.480 1.00 38.04 ?  880  HOH B O    1 
HETATM 13076 O O    . HOH F 3 .   ? 9.209   47.144  25.565 1.00 34.41 ?  881  HOH B O    1 
HETATM 13077 O O    . HOH F 3 .   ? 21.016  37.073  34.807 1.00 40.75 ?  882  HOH B O    1 
HETATM 13078 O O    . HOH F 3 .   ? 17.727  38.816  50.465 1.00 38.62 ?  883  HOH B O    1 
HETATM 13079 O O    . HOH F 3 .   ? -12.006 36.140  23.562 1.00 34.62 ?  884  HOH B O    1 
HETATM 13080 O O    . HOH F 3 .   ? -9.667  30.034  38.060 1.00 35.09 ?  885  HOH B O    1 
HETATM 13081 O O    . HOH F 3 .   ? 11.233  24.731  57.033 1.00 27.28 ?  886  HOH B O    1 
HETATM 13082 O O    . HOH F 3 .   ? 10.952  50.866  32.893 1.00 25.39 ?  887  HOH B O    1 
HETATM 13083 O O    . HOH F 3 .   ? 2.251   42.931  22.131 1.00 28.76 ?  888  HOH B O    1 
HETATM 13084 O O    . HOH F 3 .   ? -35.614 31.632  54.032 1.00 43.21 ?  889  HOH B O    1 
HETATM 13085 O O    . HOH F 3 .   ? -13.572 50.983  66.236 1.00 37.54 ?  890  HOH B O    1 
HETATM 13086 O O    . HOH F 3 .   ? 13.881  51.731  48.626 1.00 29.13 ?  891  HOH B O    1 
HETATM 13087 O O    . HOH F 3 .   ? 18.447  22.706  43.722 1.00 36.43 ?  892  HOH B O    1 
HETATM 13088 O O    . HOH F 3 .   ? -8.925  31.256  46.765 1.00 14.52 ?  893  HOH B O    1 
HETATM 13089 O O    . HOH F 3 .   ? 16.005  49.588  51.576 1.00 43.36 ?  894  HOH B O    1 
HETATM 13090 O O    . HOH F 3 .   ? -3.471  28.952  49.243 1.00 16.40 ?  895  HOH B O    1 
HETATM 13091 O O    . HOH F 3 .   ? -11.321 18.264  61.532 1.00 42.76 ?  896  HOH B O    1 
HETATM 13092 O O    . HOH F 3 .   ? -19.589 15.788  39.478 1.00 40.38 ?  897  HOH B O    1 
HETATM 13093 O O    . HOH F 3 .   ? -0.041  45.716  68.719 1.00 34.57 ?  898  HOH B O    1 
HETATM 13094 O O    . HOH F 3 .   ? -27.130 53.960  40.874 1.00 39.13 ?  899  HOH B O    1 
HETATM 13095 O O    . HOH F 3 .   ? -18.129 25.479  40.213 1.00 30.44 ?  900  HOH B O    1 
HETATM 13096 O O    . HOH F 3 .   ? 0.159   36.032  27.648 1.00 27.15 ?  901  HOH B O    1 
HETATM 13097 O O    . HOH F 3 .   ? -17.813 52.084  32.194 1.00 20.50 ?  902  HOH B O    1 
HETATM 13098 O O    . HOH F 3 .   ? 1.749   36.548  25.517 1.00 33.92 ?  903  HOH B O    1 
HETATM 13099 O O    . HOH F 3 .   ? -16.608 39.181  24.564 1.00 32.31 ?  904  HOH B O    1 
HETATM 13100 O O    . HOH F 3 .   ? -4.545  25.269  49.122 1.00 39.88 ?  905  HOH B O    1 
HETATM 13101 O O    . HOH F 3 .   ? -4.156  34.388  33.420 1.00 15.03 ?  906  HOH B O    1 
HETATM 13102 O O    . HOH F 3 .   ? -25.951 46.737  45.434 1.00 26.36 ?  907  HOH B O    1 
HETATM 13103 O O    . HOH F 3 .   ? 8.593   48.526  17.883 1.00 43.80 ?  908  HOH B O    1 
HETATM 13104 O O    . HOH F 3 .   ? 21.208  19.697  33.521 1.00 36.52 ?  909  HOH B O    1 
HETATM 13105 O O    . HOH F 3 .   ? 9.666   57.059  46.130 1.00 26.84 ?  910  HOH B O    1 
HETATM 13106 O O    . HOH F 3 .   ? -12.263 28.750  44.848 1.00 30.48 ?  911  HOH B O    1 
HETATM 13107 O O    . HOH F 3 .   ? 9.167   56.343  42.558 1.00 36.11 ?  912  HOH B O    1 
HETATM 13108 O O    . HOH F 3 .   ? -17.033 52.657  51.489 1.00 17.31 ?  913  HOH B O    1 
HETATM 13109 O O    . HOH F 3 .   ? 6.525   57.263  41.601 1.00 35.21 ?  914  HOH B O    1 
HETATM 13110 O O    . HOH F 3 .   ? -19.812 38.908  49.799 1.00 17.19 ?  915  HOH B O    1 
HETATM 13111 O O    . HOH F 3 .   ? -25.545 27.848  40.747 1.00 25.33 ?  916  HOH B O    1 
HETATM 13112 O O    . HOH F 3 .   ? 0.469   24.743  52.151 1.00 15.60 ?  917  HOH B O    1 
HETATM 13113 O O    . HOH F 3 .   ? -22.142 50.893  57.716 1.00 39.85 ?  918  HOH B O    1 
HETATM 13114 O O    . HOH F 3 .   ? -27.965 35.629  43.891 1.00 33.19 ?  919  HOH B O    1 
HETATM 13115 O O    . HOH F 3 .   ? -28.106 43.675  34.644 1.00 31.39 ?  920  HOH B O    1 
HETATM 13116 O O    . HOH F 3 .   ? -23.791 46.530  51.730 1.00 34.53 ?  921  HOH B O    1 
HETATM 13117 O O    . HOH F 3 .   ? -10.242 42.225  22.786 1.00 34.43 ?  922  HOH B O    1 
HETATM 13118 O O    . HOH F 3 .   ? 16.828  36.733  24.710 1.00 33.46 ?  923  HOH B O    1 
HETATM 13119 O O    . HOH F 3 .   ? -5.889  52.156  24.997 1.00 35.94 ?  924  HOH B O    1 
HETATM 13120 O O    . HOH F 3 .   ? 2.777   51.843  28.018 1.00 37.21 ?  925  HOH B O    1 
HETATM 13121 O O    . HOH F 3 .   ? -28.578 26.831  34.918 1.00 32.57 ?  926  HOH B O    1 
HETATM 13122 O O    . HOH F 3 .   ? -26.050 49.462  46.367 1.00 35.55 ?  927  HOH B O    1 
HETATM 13123 O O    . HOH F 3 .   ? -5.992  29.201  48.021 1.00 14.28 ?  928  HOH B O    1 
HETATM 13124 O O    . HOH F 3 .   ? -19.338 33.682  75.792 1.00 40.06 ?  929  HOH B O    1 
HETATM 13125 O O    . HOH F 3 .   ? -32.714 37.434  58.778 1.00 36.22 ?  930  HOH B O    1 
HETATM 13126 O O    . HOH F 3 .   ? -22.762 37.993  32.810 1.00 37.01 ?  931  HOH B O    1 
HETATM 13127 O O    . HOH F 3 .   ? -20.294 44.443  27.689 1.00 37.01 ?  932  HOH B O    1 
HETATM 13128 O O    . HOH F 3 .   ? -3.274  31.510  31.985 1.00 31.63 ?  933  HOH B O    1 
HETATM 13129 O O    . HOH F 3 .   ? -5.908  47.081  23.354 1.00 33.24 ?  934  HOH B O    1 
HETATM 13130 O O    . HOH F 3 .   ? 7.672   37.203  68.275 1.00 22.75 ?  935  HOH B O    1 
HETATM 13131 O O    . HOH F 3 .   ? -18.012 50.598  55.842 1.00 25.38 ?  936  HOH B O    1 
HETATM 13132 O O    . HOH F 3 .   ? -29.533 47.758  39.789 1.00 38.31 ?  937  HOH B O    1 
HETATM 13133 O O    . HOH F 3 .   ? 1.259   21.724  64.978 1.00 19.48 ?  938  HOH B O    1 
HETATM 13134 O O    . HOH F 3 .   ? -7.594  52.606  65.039 1.00 37.07 ?  939  HOH B O    1 
HETATM 13135 O O    . HOH F 3 .   ? -13.185 46.659  77.488 1.00 43.69 ?  940  HOH B O    1 
HETATM 13136 O O    . HOH F 3 .   ? 4.109   37.405  26.589 1.00 20.59 ?  941  HOH B O    1 
HETATM 13137 O O    . HOH F 3 .   ? -12.966 24.489  52.079 1.00 38.24 ?  942  HOH B O    1 
HETATM 13138 O O    . HOH F 3 .   ? -18.545 52.991  57.167 1.00 28.73 ?  943  HOH B O    1 
HETATM 13139 O O    . HOH F 3 .   ? -13.160 18.629  56.088 1.00 46.42 ?  944  HOH B O    1 
HETATM 13140 O O    . HOH F 3 .   ? 15.120  26.264  25.557 1.00 26.60 ?  945  HOH B O    1 
HETATM 13141 O O    . HOH F 3 .   ? 17.044  39.037  24.355 1.00 36.70 ?  946  HOH B O    1 
HETATM 13142 O O    . HOH F 3 .   ? -5.403  33.731  30.519 1.00 24.24 ?  947  HOH B O    1 
HETATM 13143 O O    . HOH F 3 .   ? -31.406 41.440  59.542 1.00 35.98 ?  948  HOH B O    1 
HETATM 13144 O O    . HOH F 3 .   ? 13.688  32.794  56.586 1.00 27.98 ?  949  HOH B O    1 
HETATM 13145 O O    . HOH F 3 .   ? 10.252  36.654  21.896 1.00 36.78 ?  950  HOH B O    1 
HETATM 13146 O O    . HOH F 3 .   ? -26.826 45.346  55.233 1.00 38.77 ?  951  HOH B O    1 
HETATM 13147 O O    . HOH F 3 .   ? -10.278 27.667  49.760 1.00 22.67 ?  952  HOH B O    1 
HETATM 13148 O O    . HOH F 3 .   ? 14.735  24.271  50.244 1.00 30.11 ?  953  HOH B O    1 
HETATM 13149 O O    . HOH F 3 .   ? 11.525  52.937  34.626 1.00 28.17 ?  954  HOH B O    1 
HETATM 13150 O O    . HOH F 3 .   ? -24.127 57.692  39.471 1.00 35.52 ?  955  HOH B O    1 
HETATM 13151 O O    . HOH F 3 .   ? 19.357  33.582  33.414 1.00 23.58 ?  956  HOH B O    1 
HETATM 13152 O O    . HOH F 3 .   ? -29.200 41.731  47.423 1.00 35.32 ?  957  HOH B O    1 
HETATM 13153 O O    . HOH F 3 .   ? -12.139 29.974  38.341 1.00 33.59 ?  958  HOH B O    1 
HETATM 13154 O O    . HOH F 3 .   ? 22.339  31.126  38.749 1.00 22.82 ?  959  HOH B O    1 
HETATM 13155 O O    . HOH F 3 .   ? 3.009   46.160  20.027 1.00 42.13 ?  960  HOH B O    1 
HETATM 13156 O O    . HOH F 3 .   ? 11.113  23.320  59.459 1.00 17.39 ?  961  HOH B O    1 
HETATM 13157 O O    . HOH F 3 .   ? 4.038   50.064  31.906 1.00 14.55 ?  962  HOH B O    1 
HETATM 13158 O O    . HOH F 3 .   ? -0.563  51.615  33.188 1.00 26.82 ?  963  HOH B O    1 
HETATM 13159 O O    . HOH F 3 .   ? 21.555  38.608  39.947 1.00 26.44 ?  964  HOH B O    1 
HETATM 13160 O O    . HOH F 3 .   ? 12.976  35.631  58.550 1.00 34.58 ?  965  HOH B O    1 
HETATM 13161 O O    . HOH F 3 .   ? 15.239  46.476  54.508 1.00 47.62 ?  966  HOH B O    1 
HETATM 13162 O O    . HOH F 3 .   ? 16.752  48.215  49.273 1.00 35.82 ?  967  HOH B O    1 
HETATM 13163 O O    . HOH F 3 .   ? 2.925   33.639  28.104 1.00 19.74 ?  968  HOH B O    1 
HETATM 13164 O O    . HOH F 3 .   ? 2.340   43.291  67.073 1.00 41.13 ?  969  HOH B O    1 
HETATM 13165 O O    . HOH F 3 .   ? -28.183 37.104  41.559 1.00 38.00 ?  970  HOH B O    1 
HETATM 13166 O O    . HOH F 3 .   ? 0.756   53.084  31.679 1.00 35.14 ?  971  HOH B O    1 
HETATM 13167 O O    . HOH F 3 .   ? 14.223  26.197  60.244 1.00 23.70 ?  972  HOH B O    1 
HETATM 13168 O O    . HOH F 3 .   ? 6.371   19.653  56.020 1.00 26.63 ?  973  HOH B O    1 
HETATM 13169 O O    . HOH F 3 .   ? 0.592   47.055  22.941 1.00 36.76 ?  974  HOH B O    1 
HETATM 13170 O O    . HOH F 3 .   ? 24.568  34.013  44.075 1.00 32.03 ?  975  HOH B O    1 
HETATM 13171 O O    . HOH F 3 .   ? 13.817  52.325  51.187 1.00 40.55 ?  976  HOH B O    1 
HETATM 13172 O O    . HOH F 3 .   ? -13.337 38.402  22.713 1.00 34.25 ?  977  HOH B O    1 
HETATM 13173 O O    . HOH F 3 .   ? 6.429   31.013  26.660 1.00 29.52 ?  978  HOH B O    1 
HETATM 13174 O O    . HOH F 3 .   ? 11.756  23.433  54.794 1.00 37.88 ?  979  HOH B O    1 
HETATM 13175 O O    . HOH F 3 .   ? 8.662   44.477  60.749 1.00 40.44 ?  980  HOH B O    1 
HETATM 13176 O O    . HOH F 3 .   ? 4.519   50.085  29.220 1.00 18.84 ?  981  HOH B O    1 
HETATM 13177 O O    . HOH F 3 .   ? 21.094  41.336  35.595 1.00 31.33 ?  982  HOH B O    1 
HETATM 13178 O O    . HOH F 3 .   ? -30.258 20.159  37.986 1.00 26.92 ?  983  HOH B O    1 
HETATM 13179 O O    . HOH F 3 .   ? -23.151 36.157  36.434 1.00 21.86 ?  984  HOH B O    1 
HETATM 13180 O O    . HOH F 3 .   ? 4.230   30.097  66.540 1.00 17.06 ?  985  HOH B O    1 
HETATM 13181 O O    . HOH F 3 .   ? -15.117 51.494  63.992 1.00 26.32 ?  986  HOH B O    1 
HETATM 13182 O O    . HOH F 3 .   ? 11.153  56.126  41.946 1.00 42.87 ?  987  HOH B O    1 
HETATM 13183 O O    . HOH F 3 .   ? 13.521  29.080  54.785 1.00 28.01 ?  988  HOH B O    1 
HETATM 13184 O O    . HOH F 3 .   ? -31.605 38.634  72.175 1.00 42.07 ?  989  HOH B O    1 
HETATM 13185 O O    . HOH F 3 .   ? 16.324  27.768  60.994 1.00 23.32 ?  990  HOH B O    1 
HETATM 13186 O O    . HOH F 3 .   ? 4.143   43.852  20.834 1.00 32.42 ?  991  HOH B O    1 
HETATM 13187 O O    . HOH F 3 .   ? -20.385 33.510  31.268 1.00 33.38 ?  992  HOH B O    1 
HETATM 13188 O O    . HOH F 3 .   ? -18.159 31.750  77.648 1.00 35.01 ?  993  HOH B O    1 
HETATM 13189 O O    . HOH F 3 .   ? -20.542 42.544  27.244 1.00 35.05 ?  994  HOH B O    1 
HETATM 13190 O O    . HOH F 3 .   ? 11.316  55.903  39.118 1.00 38.30 ?  995  HOH B O    1 
HETATM 13191 O O    . HOH F 3 .   ? 1.638   58.982  36.462 1.00 39.83 ?  996  HOH B O    1 
HETATM 13192 O O    . HOH F 3 .   ? -18.426 51.148  53.424 1.00 33.46 ?  997  HOH B O    1 
HETATM 13193 O O    . HOH F 3 .   ? -2.640  52.930  34.003 1.00 28.85 ?  998  HOH B O    1 
HETATM 13194 O O    . HOH F 3 .   ? -10.379 30.829  44.448 1.00 25.67 ?  999  HOH B O    1 
HETATM 13195 O O    . HOH F 3 .   ? -30.514 40.266  64.582 1.00 35.49 ?  1000 HOH B O    1 
HETATM 13196 O O    . HOH F 3 .   ? -20.396 15.464  36.840 1.00 31.60 ?  1001 HOH B O    1 
HETATM 13197 O O    . HOH F 3 .   ? -7.641  48.298  66.463 1.00 35.04 ?  1002 HOH B O    1 
HETATM 13198 O O    . HOH F 3 .   ? -12.814 21.880  75.022 1.00 26.46 ?  1003 HOH B O    1 
HETATM 13199 O O    . HOH F 3 .   ? -31.251 22.004  48.789 1.00 34.87 ?  1004 HOH B O    1 
HETATM 13200 O O    . HOH F 3 .   ? -16.468 21.865  32.798 1.00 13.50 ?  1005 HOH B O    1 
HETATM 13201 O O    . HOH F 3 .   ? 14.326  37.130  55.364 1.00 35.44 ?  1006 HOH B O    1 
HETATM 13202 O O    . HOH F 3 .   ? 9.617   39.336  67.692 1.00 38.94 ?  1007 HOH B O    1 
HETATM 13203 O O    . HOH F 3 .   ? -20.714 49.031  56.644 1.00 31.38 ?  1008 HOH B O    1 
HETATM 13204 O O    . HOH F 3 .   ? -9.791  28.565  47.121 1.00 23.01 ?  1009 HOH B O    1 
HETATM 13205 O O    . HOH F 3 .   ? -23.121 55.505  38.378 1.00 33.77 ?  1010 HOH B O    1 
HETATM 13206 O O    . HOH F 3 .   ? -14.732 25.218  43.813 1.00 39.23 ?  1011 HOH B O    1 
HETATM 13207 O O    . HOH F 3 .   ? -37.253 30.782  52.048 1.00 25.12 ?  1012 HOH B O    1 
HETATM 13208 O O    . HOH F 3 .   ? 11.067  54.358  35.885 1.00 37.98 ?  1013 HOH B O    1 
HETATM 13209 O O    . HOH F 3 .   ? 4.288   53.528  54.976 1.00 32.12 ?  1014 HOH B O    1 
HETATM 13210 O O    . HOH F 3 .   ? -32.375 23.065  46.655 1.00 29.52 ?  1015 HOH B O    1 
HETATM 13211 O O    . HOH F 3 .   ? 11.009  23.897  36.377 1.00 29.10 ?  1016 HOH B O    1 
HETATM 13212 O O    . HOH F 3 .   ? 23.480  29.695  35.261 1.00 40.03 ?  1017 HOH B O    1 
HETATM 13213 O O    . HOH F 3 .   ? -25.636 48.922  56.054 1.00 45.44 ?  1018 HOH B O    1 
HETATM 13214 O O    . HOH F 3 .   ? 13.074  18.638  28.608 1.00 33.31 ?  1019 HOH B O    1 
HETATM 13215 O O    . HOH F 3 .   ? 7.753   48.281  27.401 1.00 25.24 ?  1020 HOH B O    1 
HETATM 13216 O O    . HOH F 3 .   ? 8.583   56.085  36.737 1.00 37.08 ?  1021 HOH B O    1 
HETATM 13217 O O    . HOH F 3 .   ? -12.604 25.127  47.006 1.00 38.39 ?  1022 HOH B O    1 
HETATM 13218 O O    . HOH F 3 .   ? -23.126 26.106  34.677 1.00 32.26 ?  1023 HOH B O    1 
HETATM 13219 O O    . HOH F 3 .   ? 14.030  23.728  24.666 1.00 33.22 ?  1024 HOH B O    1 
HETATM 13220 O O    . HOH F 3 .   ? -29.416 31.022  60.131 1.00 28.12 ?  1025 HOH B O    1 
HETATM 13221 O O    . HOH F 3 .   ? -15.850 51.271  67.910 1.00 40.24 ?  1026 HOH B O    1 
HETATM 13222 O O    . HOH F 3 .   ? -9.492  17.499  59.894 1.00 36.35 ?  1027 HOH B O    1 
HETATM 13223 O O    . HOH F 3 .   ? 14.234  46.400  56.255 1.00 46.56 ?  1028 HOH B O    1 
HETATM 13224 O O    . HOH F 3 .   ? 15.179  50.248  33.113 1.00 25.30 ?  1029 HOH B O    1 
HETATM 13225 O O    . HOH F 3 .   ? -30.001 44.721  44.327 1.00 41.69 ?  1030 HOH B O    1 
HETATM 13226 O O    . HOH F 3 .   ? -31.130 21.063  39.612 1.00 31.25 ?  1031 HOH B O    1 
HETATM 13227 O O    . HOH F 3 .   ? -21.953 37.717  30.698 1.00 32.96 ?  1032 HOH B O    1 
HETATM 13228 O O    . HOH F 3 .   ? 1.527   47.498  67.686 1.00 40.09 ?  1033 HOH B O    1 
HETATM 13229 O O    . HOH F 3 .   ? -1.806  33.848  28.008 1.00 41.08 ?  1034 HOH B O    1 
HETATM 13230 O O    . HOH F 3 .   ? -21.427 33.438  77.505 1.00 41.61 ?  1035 HOH B O    1 
HETATM 13231 O O    . HOH F 3 .   ? 9.457   21.837  55.352 1.00 28.47 ?  1036 HOH B O    1 
HETATM 13232 O O    . HOH F 3 .   ? -8.754  20.195  73.150 1.00 32.02 ?  1037 HOH B O    1 
HETATM 13233 O O    . HOH F 3 .   ? 12.863  54.193  47.381 1.00 30.02 ?  1038 HOH B O    1 
HETATM 13234 O O    . HOH F 3 .   ? -2.969  60.269  45.301 1.00 23.98 ?  1039 HOH B O    1 
HETATM 13235 O O    . HOH F 3 .   ? -30.654 28.333  58.813 1.00 34.80 ?  1040 HOH B O    1 
HETATM 13236 O O    . HOH F 3 .   ? -4.132  45.862  22.445 1.00 39.78 ?  1041 HOH B O    1 
HETATM 13237 O O    . HOH F 3 .   ? 14.326  52.731  34.092 1.00 33.63 ?  1042 HOH B O    1 
HETATM 13238 O O    . HOH F 3 .   ? 14.911  31.421  53.758 1.00 33.40 ?  1043 HOH B O    1 
HETATM 13239 O O    . HOH F 3 .   ? 9.105   22.645  38.264 1.00 32.00 ?  1044 HOH B O    1 
HETATM 13240 O O    . HOH F 3 .   ? -15.325 48.013  21.310 1.00 24.35 ?  1045 HOH B O    1 
HETATM 13241 O O    . HOH F 3 .   ? -25.352 39.313  33.454 1.00 33.27 ?  1046 HOH B O    1 
HETATM 13242 O O    . HOH F 3 .   ? -22.201 48.533  54.539 1.00 36.47 ?  1047 HOH B O    1 
HETATM 13243 O O    . HOH F 3 .   ? 0.629   61.409  38.725 1.00 39.38 ?  1048 HOH B O    1 
HETATM 13244 O O    . HOH F 3 .   ? -31.146 44.455  64.963 1.00 36.36 ?  1049 HOH B O    1 
HETATM 13245 O O    . HOH F 3 .   ? 12.952  30.183  25.186 1.00 32.73 ?  1050 HOH B O    1 
HETATM 13246 O O    . HOH F 3 .   ? -9.275  16.259  73.386 1.00 43.93 ?  1051 HOH B O    1 
HETATM 13247 O O    . HOH F 3 .   ? 3.142   59.274  38.346 1.00 39.51 ?  1052 HOH B O    1 
HETATM 13248 O O    . HOH F 3 .   ? -27.019 18.368  64.499 1.00 24.24 ?  1053 HOH B O    1 
HETATM 13249 O O    . HOH F 3 .   ? 5.462   19.769  53.293 1.00 20.38 ?  1054 HOH B O    1 
HETATM 13250 O O    . HOH F 3 .   ? 15.932  27.295  63.603 1.00 16.99 ?  1055 HOH B O    1 
HETATM 13251 O O    . HOH F 3 .   ? -18.368 45.651  24.145 1.00 22.38 ?  1056 HOH B O    1 
HETATM 13252 O O    . HOH F 3 .   ? 13.206  48.212  29.528 1.00 30.79 ?  1057 HOH B O    1 
HETATM 13253 O O    . HOH F 3 .   ? -18.573 50.964  66.652 1.00 29.48 ?  1058 HOH B O    1 
HETATM 13254 O O    . HOH F 3 .   ? -1.476  26.071  39.088 1.00 21.52 ?  1059 HOH B O    1 
HETATM 13255 O O    . HOH F 3 .   ? -17.385 21.400  38.854 1.00 38.19 ?  1060 HOH B O    1 
HETATM 13256 O O    . HOH F 3 .   ? -36.800 28.111  51.410 1.00 24.70 ?  1061 HOH B O    1 
HETATM 13257 O O    . HOH F 3 .   ? -2.574  26.590  50.300 1.00 22.51 ?  1062 HOH B O    1 
HETATM 13258 O O    . HOH F 3 .   ? -2.543  34.713  71.972 1.00 35.27 ?  1063 HOH B O    1 
HETATM 13259 O O    . HOH F 3 .   ? 2.630   33.837  68.334 1.00 27.77 ?  1064 HOH B O    1 
HETATM 13260 O O    . HOH F 3 .   ? -23.894 51.428  49.870 1.00 37.18 ?  1065 HOH B O    1 
HETATM 13261 O O    . HOH F 3 .   ? 0.010   55.765  31.923 1.00 39.19 ?  1066 HOH B O    1 
HETATM 13262 O O    . HOH F 3 .   ? 7.680   30.510  24.299 1.00 34.19 ?  1067 HOH B O    1 
HETATM 13263 O O    . HOH F 3 .   ? -31.891 20.905  42.158 1.00 34.00 ?  1068 HOH B O    1 
HETATM 13264 O O    . HOH F 3 .   ? 13.678  26.456  53.436 1.00 26.66 ?  1069 HOH B O    1 
HETATM 13265 O O    . HOH F 3 .   ? 21.217  31.246  36.136 1.00 33.91 ?  1070 HOH B O    1 
HETATM 13266 O O    . HOH F 3 .   ? -2.408  54.796  66.925 1.00 46.26 ?  1071 HOH B O    1 
HETATM 13267 O O    . HOH F 3 .   ? 0.452   59.777  43.137 1.00 25.88 ?  1072 HOH B O    1 
HETATM 13268 O O    . HOH F 3 .   ? -24.657 35.279  38.302 1.00 35.46 ?  1073 HOH B O    1 
HETATM 13269 O O    . HOH F 3 .   ? -24.434 27.861  36.208 1.00 28.29 ?  1074 HOH B O    1 
HETATM 13270 O O    . HOH F 3 .   ? 19.961  42.518  32.819 1.00 33.59 ?  1075 HOH B O    1 
HETATM 13271 O O    . HOH F 3 .   ? 9.431   34.536  25.480 1.00 30.69 ?  1076 HOH B O    1 
HETATM 13272 O O    . HOH F 3 .   ? 8.470   50.907  31.568 1.00 21.01 ?  1077 HOH B O    1 
HETATM 13273 O O    . HOH F 3 .   ? 0.110   34.189  71.730 1.00 37.58 ?  1078 HOH B O    1 
HETATM 13274 O O    . HOH F 3 .   ? -9.738  38.109  78.032 1.00 36.39 ?  1079 HOH B O    1 
HETATM 13275 O O    . HOH F 3 .   ? 12.813  37.199  60.269 1.00 41.20 ?  1080 HOH B O    1 
HETATM 13276 O O    . HOH F 3 .   ? -4.450  31.968  74.048 1.00 25.80 ?  1081 HOH B O    1 
HETATM 13277 O O    . HOH F 3 .   ? -24.828 41.220  30.608 1.00 42.56 ?  1082 HOH B O    1 
HETATM 13278 O O    . HOH F 3 .   ? 16.188  35.292  56.476 1.00 45.72 ?  1083 HOH B O    1 
HETATM 13279 O O    . HOH F 3 .   ? -29.123 17.263  41.413 1.00 40.64 ?  1084 HOH B O    1 
HETATM 13280 O O    . HOH F 3 .   ? -31.931 40.884  62.659 1.00 34.37 ?  1085 HOH B O    1 
HETATM 13281 O O    . HOH F 3 .   ? 6.670   33.881  26.528 1.00 26.49 ?  1086 HOH B O    1 
HETATM 13282 O O    . HOH F 3 .   ? -5.948  29.548  43.521 1.00 14.70 ?  1087 HOH B O    1 
HETATM 13283 O O    . HOH F 3 .   ? 15.285  35.799  22.320 1.00 31.64 ?  1088 HOH B O    1 
HETATM 13284 O O    . HOH F 3 .   ? 16.877  39.473  21.784 1.00 40.11 ?  1089 HOH B O    1 
HETATM 13285 O O    . HOH F 3 .   ? -24.516 43.104  29.978 1.00 43.32 ?  1090 HOH B O    1 
HETATM 13286 O O    . HOH F 3 .   ? -7.655  28.605  37.563 1.00 35.65 ?  1091 HOH B O    1 
HETATM 13287 O O    . HOH F 3 .   ? -10.348 28.319  39.195 1.00 40.58 ?  1092 HOH B O    1 
HETATM 13288 O O    . HOH F 3 .   ? -15.273 22.357  34.984 1.00 34.25 ?  1093 HOH B O    1 
HETATM 13289 O O    . HOH F 3 .   ? 16.238  26.750  53.089 1.00 33.00 ?  1094 HOH B O    1 
HETATM 13290 O O    . HOH F 3 .   ? 5.506   34.535  24.272 1.00 35.78 ?  1095 HOH B O    1 
HETATM 13291 O O    . HOH F 3 .   ? -4.167  27.693  44.427 1.00 13.79 ?  1096 HOH B O    1 
HETATM 13292 O O    . HOH F 3 .   ? 9.227   49.626  29.222 1.00 29.95 ?  1097 HOH B O    1 
HETATM 13293 O O    . HOH F 3 .   ? 16.606  50.267  30.431 1.00 42.20 ?  1098 HOH B O    1 
HETATM 13294 O O    . HOH F 3 .   ? -5.576  26.774  46.733 1.00 26.65 ?  1099 HOH B O    1 
HETATM 13295 O O    . HOH F 3 .   ? -10.632 35.025  21.319 1.00 35.75 ?  1100 HOH B O    1 
HETATM 13296 O O    . HOH F 3 .   ? -9.445  28.672  41.177 1.00 38.25 ?  1101 HOH B O    1 
HETATM 13297 O O    . HOH F 3 .   ? -14.215 20.003  35.602 1.00 23.00 ?  1102 HOH B O    1 
HETATM 13298 O O    . HOH F 3 .   ? -8.571  28.681  43.544 1.00 24.06 ?  1103 HOH B O    1 
HETATM 13299 O O    . HOH F 3 .   ? -8.434  26.735  45.924 1.00 36.37 ?  1104 HOH B O    1 
HETATM 13300 O O    . HOH F 3 .   ? 13.631  21.627  55.953 1.00 42.91 ?  1105 HOH B O    1 
HETATM 13301 O O    . HOH F 3 .   ? -14.635 19.957  38.306 1.00 39.36 ?  1106 HOH B O    1 
HETATM 13302 O O    . HOH F 3 .   ? -7.286  27.817  40.119 1.00 31.77 ?  1107 HOH B O    1 
HETATM 13303 O O    . HOH F 3 .   ? -7.008  26.182  37.666 1.00 25.72 ?  1108 HOH B O    1 
HETATM 13304 O O    . HOH F 3 .   ? -11.722 20.807  36.063 1.00 30.40 ?  1109 HOH B O    1 
HETATM 13305 O O    . HOH F 3 .   ? -8.565  24.004  37.613 1.00 29.31 ?  1110 HOH B O    1 
# 
