data_9JLY
# 
_entry.id   9JLY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JLY         pdb_00009jly 10.2210/pdb9jly/pdb 
WWPDB D_1300051652 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-18 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JLY 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              liyaoyao@sdu.edu.cn 
_pdbx_contact_author.name_first         Yaoyao 
_pdbx_contact_author.name_last          Li 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8762-9615 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, Y.'  1 0000-0002-8762-9615 
'Zhu, D.' 2 0000-0002-2949-9410 
'Xie, X.' 3 0000-0002-5118-6111 
'Li, F.'  4 0009-0009-0724-7915 
'Lu, M.'  5 0009-0000-1359-6323 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Am.Chem.Soc. 
_citation.journal_id_ASTM           JACSAT 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1520-5126 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            147 
_citation.language                  ? 
_citation.page_first                19253 
_citation.page_last                 19261 
_citation.title                     
;Structural Basis for Medium-Chain Dehydrogenase/Reductase-Catalyzed Reductive Cyclization in Polycyclic Tetramate Macrolactam Biosynthesis.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacs.5c04971 
_citation.pdbx_database_id_PubMed   40406958 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xie, X.'  1  0000-0002-5118-6111 
primary 'Li, F.'   2  ?                   
primary 'Mu, Y.'   3  ?                   
primary 'Lu, M.'   4  ?                   
primary 'Luo, J.'  5  ?                   
primary 'Wang, H.' 6  0000-0002-1779-0286 
primary 'Shen, Y.' 7  0000-0002-3881-0135 
primary 'Du, L.'   8  0000-0003-4048-1008 
primary 'Zhu, D.'  9  0000-0002-2949-9410 
primary 'Li, Y.'   10 0000-0002-8762-9615 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'NADP-dependent oxidoreductase'                    38943.332 2 ? ? ? ? 
2 non-polymer syn 'NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE' 743.405   2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Oxidoreductase,zinc-binding dehydrogenase family protein' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;LGSMKTERWVVREHVEGVPDAARIYEKVETELNTRLGEEQMLLKTLYVSVDPYLQGICLDTPIGDHMGADSIMQVLDAGP
NAPFRPGDLVQGFGGWRTHLVSDGKPKLWQTGTFPMVFPAYRKLDLRHYDDALPLSTALGVMGGPGMTAWGTMTKFMQVR
PGDTVVVSGASGMIGTLVGQMAKRAGARVVGTAGSAGKARYLSQLGFDAVIDYKLADDADKMREALREAAPDGVDKYFDS
IGGSVTDAVFSMLNVGSQVAVCWQWATQVQRDYHGPRLLPYIMFPRATIRGIFSLEWFTEQNWSALHEELGGLVRRQELV
AHETVQDGFEHIPAAYQTLFSASESNRGKVLVRV
;
_entity_poly.pdbx_seq_one_letter_code_can   
;LGSMKTERWVVREHVEGVPDAARIYEKVETELNTRLGEEQMLLKTLYVSVDPYLQGICLDTPIGDHMGADSIMQVLDAGP
NAPFRPGDLVQGFGGWRTHLVSDGKPKLWQTGTFPMVFPAYRKLDLRHYDDALPLSTALGVMGGPGMTAWGTMTKFMQVR
PGDTVVVSGASGMIGTLVGQMAKRAGARVVGTAGSAGKARYLSQLGFDAVIDYKLADDADKMREALREAAPDGVDKYFDS
IGGSVTDAVFSMLNVGSQVAVCWQWATQVQRDYHGPRLLPYIMFPRATIRGIFSLEWFTEQNWSALHEELGGLVRRQELV
AHETVQDGFEHIPAAYQTLFSASESNRGKVLVRV
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE' 
_pdbx_entity_nonpoly.comp_id     NAP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LEU n 
1 2   GLY n 
1 3   SER n 
1 4   MET n 
1 5   LYS n 
1 6   THR n 
1 7   GLU n 
1 8   ARG n 
1 9   TRP n 
1 10  VAL n 
1 11  VAL n 
1 12  ARG n 
1 13  GLU n 
1 14  HIS n 
1 15  VAL n 
1 16  GLU n 
1 17  GLY n 
1 18  VAL n 
1 19  PRO n 
1 20  ASP n 
1 21  ALA n 
1 22  ALA n 
1 23  ARG n 
1 24  ILE n 
1 25  TYR n 
1 26  GLU n 
1 27  LYS n 
1 28  VAL n 
1 29  GLU n 
1 30  THR n 
1 31  GLU n 
1 32  LEU n 
1 33  ASN n 
1 34  THR n 
1 35  ARG n 
1 36  LEU n 
1 37  GLY n 
1 38  GLU n 
1 39  GLU n 
1 40  GLN n 
1 41  MET n 
1 42  LEU n 
1 43  LEU n 
1 44  LYS n 
1 45  THR n 
1 46  LEU n 
1 47  TYR n 
1 48  VAL n 
1 49  SER n 
1 50  VAL n 
1 51  ASP n 
1 52  PRO n 
1 53  TYR n 
1 54  LEU n 
1 55  GLN n 
1 56  GLY n 
1 57  ILE n 
1 58  CYS n 
1 59  LEU n 
1 60  ASP n 
1 61  THR n 
1 62  PRO n 
1 63  ILE n 
1 64  GLY n 
1 65  ASP n 
1 66  HIS n 
1 67  MET n 
1 68  GLY n 
1 69  ALA n 
1 70  ASP n 
1 71  SER n 
1 72  ILE n 
1 73  MET n 
1 74  GLN n 
1 75  VAL n 
1 76  LEU n 
1 77  ASP n 
1 78  ALA n 
1 79  GLY n 
1 80  PRO n 
1 81  ASN n 
1 82  ALA n 
1 83  PRO n 
1 84  PHE n 
1 85  ARG n 
1 86  PRO n 
1 87  GLY n 
1 88  ASP n 
1 89  LEU n 
1 90  VAL n 
1 91  GLN n 
1 92  GLY n 
1 93  PHE n 
1 94  GLY n 
1 95  GLY n 
1 96  TRP n 
1 97  ARG n 
1 98  THR n 
1 99  HIS n 
1 100 LEU n 
1 101 VAL n 
1 102 SER n 
1 103 ASP n 
1 104 GLY n 
1 105 LYS n 
1 106 PRO n 
1 107 LYS n 
1 108 LEU n 
1 109 TRP n 
1 110 GLN n 
1 111 THR n 
1 112 GLY n 
1 113 THR n 
1 114 PHE n 
1 115 PRO n 
1 116 MET n 
1 117 VAL n 
1 118 PHE n 
1 119 PRO n 
1 120 ALA n 
1 121 TYR n 
1 122 ARG n 
1 123 LYS n 
1 124 LEU n 
1 125 ASP n 
1 126 LEU n 
1 127 ARG n 
1 128 HIS n 
1 129 TYR n 
1 130 ASP n 
1 131 ASP n 
1 132 ALA n 
1 133 LEU n 
1 134 PRO n 
1 135 LEU n 
1 136 SER n 
1 137 THR n 
1 138 ALA n 
1 139 LEU n 
1 140 GLY n 
1 141 VAL n 
1 142 MET n 
1 143 GLY n 
1 144 GLY n 
1 145 PRO n 
1 146 GLY n 
1 147 MET n 
1 148 THR n 
1 149 ALA n 
1 150 TRP n 
1 151 GLY n 
1 152 THR n 
1 153 MET n 
1 154 THR n 
1 155 LYS n 
1 156 PHE n 
1 157 MET n 
1 158 GLN n 
1 159 VAL n 
1 160 ARG n 
1 161 PRO n 
1 162 GLY n 
1 163 ASP n 
1 164 THR n 
1 165 VAL n 
1 166 VAL n 
1 167 VAL n 
1 168 SER n 
1 169 GLY n 
1 170 ALA n 
1 171 SER n 
1 172 GLY n 
1 173 MET n 
1 174 ILE n 
1 175 GLY n 
1 176 THR n 
1 177 LEU n 
1 178 VAL n 
1 179 GLY n 
1 180 GLN n 
1 181 MET n 
1 182 ALA n 
1 183 LYS n 
1 184 ARG n 
1 185 ALA n 
1 186 GLY n 
1 187 ALA n 
1 188 ARG n 
1 189 VAL n 
1 190 VAL n 
1 191 GLY n 
1 192 THR n 
1 193 ALA n 
1 194 GLY n 
1 195 SER n 
1 196 ALA n 
1 197 GLY n 
1 198 LYS n 
1 199 ALA n 
1 200 ARG n 
1 201 TYR n 
1 202 LEU n 
1 203 SER n 
1 204 GLN n 
1 205 LEU n 
1 206 GLY n 
1 207 PHE n 
1 208 ASP n 
1 209 ALA n 
1 210 VAL n 
1 211 ILE n 
1 212 ASP n 
1 213 TYR n 
1 214 LYS n 
1 215 LEU n 
1 216 ALA n 
1 217 ASP n 
1 218 ASP n 
1 219 ALA n 
1 220 ASP n 
1 221 LYS n 
1 222 MET n 
1 223 ARG n 
1 224 GLU n 
1 225 ALA n 
1 226 LEU n 
1 227 ARG n 
1 228 GLU n 
1 229 ALA n 
1 230 ALA n 
1 231 PRO n 
1 232 ASP n 
1 233 GLY n 
1 234 VAL n 
1 235 ASP n 
1 236 LYS n 
1 237 TYR n 
1 238 PHE n 
1 239 ASP n 
1 240 SER n 
1 241 ILE n 
1 242 GLY n 
1 243 GLY n 
1 244 SER n 
1 245 VAL n 
1 246 THR n 
1 247 ASP n 
1 248 ALA n 
1 249 VAL n 
1 250 PHE n 
1 251 SER n 
1 252 MET n 
1 253 LEU n 
1 254 ASN n 
1 255 VAL n 
1 256 GLY n 
1 257 SER n 
1 258 GLN n 
1 259 VAL n 
1 260 ALA n 
1 261 VAL n 
1 262 CYS n 
1 263 TRP n 
1 264 GLN n 
1 265 TRP n 
1 266 ALA n 
1 267 THR n 
1 268 GLN n 
1 269 VAL n 
1 270 GLN n 
1 271 ARG n 
1 272 ASP n 
1 273 TYR n 
1 274 HIS n 
1 275 GLY n 
1 276 PRO n 
1 277 ARG n 
1 278 LEU n 
1 279 LEU n 
1 280 PRO n 
1 281 TYR n 
1 282 ILE n 
1 283 MET n 
1 284 PHE n 
1 285 PRO n 
1 286 ARG n 
1 287 ALA n 
1 288 THR n 
1 289 ILE n 
1 290 ARG n 
1 291 GLY n 
1 292 ILE n 
1 293 PHE n 
1 294 SER n 
1 295 LEU n 
1 296 GLU n 
1 297 TRP n 
1 298 PHE n 
1 299 THR n 
1 300 GLU n 
1 301 GLN n 
1 302 ASN n 
1 303 TRP n 
1 304 SER n 
1 305 ALA n 
1 306 LEU n 
1 307 HIS n 
1 308 GLU n 
1 309 GLU n 
1 310 LEU n 
1 311 GLY n 
1 312 GLY n 
1 313 LEU n 
1 314 VAL n 
1 315 ARG n 
1 316 ARG n 
1 317 GLN n 
1 318 GLU n 
1 319 LEU n 
1 320 VAL n 
1 321 ALA n 
1 322 HIS n 
1 323 GLU n 
1 324 THR n 
1 325 VAL n 
1 326 GLN n 
1 327 ASP n 
1 328 GLY n 
1 329 PHE n 
1 330 GLU n 
1 331 HIS n 
1 332 ILE n 
1 333 PRO n 
1 334 ALA n 
1 335 ALA n 
1 336 TYR n 
1 337 GLN n 
1 338 THR n 
1 339 LEU n 
1 340 PHE n 
1 341 SER n 
1 342 ALA n 
1 343 SER n 
1 344 GLU n 
1 345 SER n 
1 346 ASN n 
1 347 ARG n 
1 348 GLY n 
1 349 LYS n 
1 350 VAL n 
1 351 LEU n 
1 352 VAL n 
1 353 ARG n 
1 354 VAL n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   354 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 GLE_3219 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Lysobacter enzymogenes' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     69 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                            ?                                            
'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                                           ?                                            
'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                                         ?                                            
'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                    ?                                            
'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                                           ?                                            
'C3 H7 N O2 S'      121.158 
GLN 'L-peptide linking' y GLUTAMINE                                          ?                                            
'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                    ?                                            
'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                                            ?                                            
'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                                          ?                                            
'C6 H10 N3 O2 1'    156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                         ?                                            
'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                                            ?                                            
'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                                             ?                                            
'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                                         ?                                            
'C5 H11 N O2 S'     149.211 
NAP non-polymer         . 'NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE' 
;2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE
;
'C21 H28 N7 O17 P3' 743.405 
PHE 'L-peptide linking' y PHENYLALANINE                                      ?                                            
'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                                            ?                                            
'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                                             ?                                            
'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                                          ?                                            
'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                         ?                                            
'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                                           ?                                            
'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                                             ?                                            
'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LEU 1   -2  -2  LEU LEU A . n 
A 1 2   GLY 2   -1  -1  GLY GLY A . n 
A 1 3   SER 3   0   0   SER SER A . n 
A 1 4   MET 4   1   1   MET MET A . n 
A 1 5   LYS 5   2   2   LYS LYS A . n 
A 1 6   THR 6   3   3   THR THR A . n 
A 1 7   GLU 7   4   4   GLU GLU A . n 
A 1 8   ARG 8   5   5   ARG ARG A . n 
A 1 9   TRP 9   6   6   TRP TRP A . n 
A 1 10  VAL 10  7   7   VAL VAL A . n 
A 1 11  VAL 11  8   8   VAL VAL A . n 
A 1 12  ARG 12  9   9   ARG ARG A . n 
A 1 13  GLU 13  10  10  GLU GLU A . n 
A 1 14  HIS 14  11  11  HIS HIS A . n 
A 1 15  VAL 15  12  12  VAL VAL A . n 
A 1 16  GLU 16  13  13  GLU GLU A . n 
A 1 17  GLY 17  14  14  GLY GLY A . n 
A 1 18  VAL 18  15  15  VAL VAL A . n 
A 1 19  PRO 19  16  16  PRO PRO A . n 
A 1 20  ASP 20  17  17  ASP ASP A . n 
A 1 21  ALA 21  18  18  ALA ALA A . n 
A 1 22  ALA 22  19  19  ALA ALA A . n 
A 1 23  ARG 23  20  20  ARG ARG A . n 
A 1 24  ILE 24  21  21  ILE ILE A . n 
A 1 25  TYR 25  22  22  TYR TYR A . n 
A 1 26  GLU 26  23  23  GLU GLU A . n 
A 1 27  LYS 27  24  24  LYS LYS A . n 
A 1 28  VAL 28  25  25  VAL VAL A . n 
A 1 29  GLU 29  26  26  GLU GLU A . n 
A 1 30  THR 30  27  27  THR THR A . n 
A 1 31  GLU 31  28  28  GLU GLU A . n 
A 1 32  LEU 32  29  29  LEU LEU A . n 
A 1 33  ASN 33  30  30  ASN ASN A . n 
A 1 34  THR 34  31  31  THR THR A . n 
A 1 35  ARG 35  32  32  ARG ARG A . n 
A 1 36  LEU 36  33  33  LEU LEU A . n 
A 1 37  GLY 37  34  34  GLY GLY A . n 
A 1 38  GLU 38  35  35  GLU GLU A . n 
A 1 39  GLU 39  36  36  GLU GLU A . n 
A 1 40  GLN 40  37  37  GLN GLN A . n 
A 1 41  MET 41  38  38  MET MET A . n 
A 1 42  LEU 42  39  39  LEU LEU A . n 
A 1 43  LEU 43  40  40  LEU LEU A . n 
A 1 44  LYS 44  41  41  LYS LYS A . n 
A 1 45  THR 45  42  42  THR THR A . n 
A 1 46  LEU 46  43  43  LEU LEU A . n 
A 1 47  TYR 47  44  44  TYR TYR A . n 
A 1 48  VAL 48  45  45  VAL VAL A . n 
A 1 49  SER 49  46  46  SER SER A . n 
A 1 50  VAL 50  47  47  VAL VAL A . n 
A 1 51  ASP 51  48  48  ASP ASP A . n 
A 1 52  PRO 52  49  49  PRO PRO A . n 
A 1 53  TYR 53  50  50  TYR TYR A . n 
A 1 54  LEU 54  51  51  LEU LEU A . n 
A 1 55  GLN 55  52  52  GLN GLN A . n 
A 1 56  GLY 56  53  53  GLY GLY A . n 
A 1 57  ILE 57  54  54  ILE ILE A . n 
A 1 58  CYS 58  55  55  CYS CYS A . n 
A 1 59  LEU 59  56  56  LEU LEU A . n 
A 1 60  ASP 60  57  57  ASP ASP A . n 
A 1 61  THR 61  58  58  THR THR A . n 
A 1 62  PRO 62  59  59  PRO PRO A . n 
A 1 63  ILE 63  60  60  ILE ILE A . n 
A 1 64  GLY 64  61  61  GLY GLY A . n 
A 1 65  ASP 65  62  62  ASP ASP A . n 
A 1 66  HIS 66  63  63  HIS HIS A . n 
A 1 67  MET 67  64  64  MET MET A . n 
A 1 68  GLY 68  65  65  GLY GLY A . n 
A 1 69  ALA 69  66  66  ALA ALA A . n 
A 1 70  ASP 70  67  67  ASP ASP A . n 
A 1 71  SER 71  68  68  SER SER A . n 
A 1 72  ILE 72  69  69  ILE ILE A . n 
A 1 73  MET 73  70  70  MET MET A . n 
A 1 74  GLN 74  71  71  GLN GLN A . n 
A 1 75  VAL 75  72  72  VAL VAL A . n 
A 1 76  LEU 76  73  73  LEU LEU A . n 
A 1 77  ASP 77  74  74  ASP ASP A . n 
A 1 78  ALA 78  75  75  ALA ALA A . n 
A 1 79  GLY 79  76  76  GLY GLY A . n 
A 1 80  PRO 80  77  77  PRO PRO A . n 
A 1 81  ASN 81  78  78  ASN ASN A . n 
A 1 82  ALA 82  79  79  ALA ALA A . n 
A 1 83  PRO 83  80  80  PRO PRO A . n 
A 1 84  PHE 84  81  81  PHE PHE A . n 
A 1 85  ARG 85  82  82  ARG ARG A . n 
A 1 86  PRO 86  83  83  PRO PRO A . n 
A 1 87  GLY 87  84  84  GLY GLY A . n 
A 1 88  ASP 88  85  85  ASP ASP A . n 
A 1 89  LEU 89  86  86  LEU LEU A . n 
A 1 90  VAL 90  87  87  VAL VAL A . n 
A 1 91  GLN 91  88  88  GLN GLN A . n 
A 1 92  GLY 92  89  89  GLY GLY A . n 
A 1 93  PHE 93  90  90  PHE PHE A . n 
A 1 94  GLY 94  91  91  GLY GLY A . n 
A 1 95  GLY 95  92  92  GLY GLY A . n 
A 1 96  TRP 96  93  93  TRP TRP A . n 
A 1 97  ARG 97  94  94  ARG ARG A . n 
A 1 98  THR 98  95  95  THR THR A . n 
A 1 99  HIS 99  96  96  HIS HIS A . n 
A 1 100 LEU 100 97  97  LEU LEU A . n 
A 1 101 VAL 101 98  98  VAL VAL A . n 
A 1 102 SER 102 99  99  SER SER A . n 
A 1 103 ASP 103 100 100 ASP ASP A . n 
A 1 104 GLY 104 101 101 GLY GLY A . n 
A 1 105 LYS 105 102 102 LYS LYS A . n 
A 1 106 PRO 106 103 103 PRO PRO A . n 
A 1 107 LYS 107 104 104 LYS LYS A . n 
A 1 108 LEU 108 105 105 LEU LEU A . n 
A 1 109 TRP 109 106 106 TRP TRP A . n 
A 1 110 GLN 110 107 107 GLN GLN A . n 
A 1 111 THR 111 108 108 THR THR A . n 
A 1 112 GLY 112 109 109 GLY GLY A . n 
A 1 113 THR 113 110 110 THR THR A . n 
A 1 114 PHE 114 111 111 PHE PHE A . n 
A 1 115 PRO 115 112 112 PRO PRO A . n 
A 1 116 MET 116 113 113 MET MET A . n 
A 1 117 VAL 117 114 114 VAL VAL A . n 
A 1 118 PHE 118 115 115 PHE PHE A . n 
A 1 119 PRO 119 116 116 PRO PRO A . n 
A 1 120 ALA 120 117 117 ALA ALA A . n 
A 1 121 TYR 121 118 118 TYR TYR A . n 
A 1 122 ARG 122 119 119 ARG ARG A . n 
A 1 123 LYS 123 120 120 LYS LYS A . n 
A 1 124 LEU 124 121 121 LEU LEU A . n 
A 1 125 ASP 125 122 122 ASP ASP A . n 
A 1 126 LEU 126 123 123 LEU LEU A . n 
A 1 127 ARG 127 124 124 ARG ARG A . n 
A 1 128 HIS 128 125 125 HIS HIS A . n 
A 1 129 TYR 129 126 126 TYR TYR A . n 
A 1 130 ASP 130 127 127 ASP ASP A . n 
A 1 131 ASP 131 128 128 ASP ASP A . n 
A 1 132 ALA 132 129 129 ALA ALA A . n 
A 1 133 LEU 133 130 130 LEU LEU A . n 
A 1 134 PRO 134 131 131 PRO PRO A . n 
A 1 135 LEU 135 132 132 LEU LEU A . n 
A 1 136 SER 136 133 133 SER SER A . n 
A 1 137 THR 137 134 134 THR THR A . n 
A 1 138 ALA 138 135 135 ALA ALA A . n 
A 1 139 LEU 139 136 136 LEU LEU A . n 
A 1 140 GLY 140 137 137 GLY GLY A . n 
A 1 141 VAL 141 138 138 VAL VAL A . n 
A 1 142 MET 142 139 139 MET MET A . n 
A 1 143 GLY 143 140 140 GLY GLY A . n 
A 1 144 GLY 144 141 141 GLY GLY A . n 
A 1 145 PRO 145 142 142 PRO PRO A . n 
A 1 146 GLY 146 143 143 GLY GLY A . n 
A 1 147 MET 147 144 144 MET MET A . n 
A 1 148 THR 148 145 145 THR THR A . n 
A 1 149 ALA 149 146 146 ALA ALA A . n 
A 1 150 TRP 150 147 147 TRP TRP A . n 
A 1 151 GLY 151 148 148 GLY GLY A . n 
A 1 152 THR 152 149 149 THR THR A . n 
A 1 153 MET 153 150 150 MET MET A . n 
A 1 154 THR 154 151 151 THR THR A . n 
A 1 155 LYS 155 152 152 LYS LYS A . n 
A 1 156 PHE 156 153 153 PHE PHE A . n 
A 1 157 MET 157 154 154 MET MET A . n 
A 1 158 GLN 158 155 155 GLN GLN A . n 
A 1 159 VAL 159 156 156 VAL VAL A . n 
A 1 160 ARG 160 157 157 ARG ARG A . n 
A 1 161 PRO 161 158 158 PRO PRO A . n 
A 1 162 GLY 162 159 159 GLY GLY A . n 
A 1 163 ASP 163 160 160 ASP ASP A . n 
A 1 164 THR 164 161 161 THR THR A . n 
A 1 165 VAL 165 162 162 VAL VAL A . n 
A 1 166 VAL 166 163 163 VAL VAL A . n 
A 1 167 VAL 167 164 164 VAL VAL A . n 
A 1 168 SER 168 165 165 SER SER A . n 
A 1 169 GLY 169 166 166 GLY GLY A . n 
A 1 170 ALA 170 167 167 ALA ALA A . n 
A 1 171 SER 171 168 168 SER SER A . n 
A 1 172 GLY 172 169 169 GLY GLY A . n 
A 1 173 MET 173 170 170 MET MET A . n 
A 1 174 ILE 174 171 171 ILE ILE A . n 
A 1 175 GLY 175 172 172 GLY GLY A . n 
A 1 176 THR 176 173 173 THR THR A . n 
A 1 177 LEU 177 174 174 LEU LEU A . n 
A 1 178 VAL 178 175 175 VAL VAL A . n 
A 1 179 GLY 179 176 176 GLY GLY A . n 
A 1 180 GLN 180 177 177 GLN GLN A . n 
A 1 181 MET 181 178 178 MET MET A . n 
A 1 182 ALA 182 179 179 ALA ALA A . n 
A 1 183 LYS 183 180 180 LYS LYS A . n 
A 1 184 ARG 184 181 181 ARG ARG A . n 
A 1 185 ALA 185 182 182 ALA ALA A . n 
A 1 186 GLY 186 183 183 GLY GLY A . n 
A 1 187 ALA 187 184 184 ALA ALA A . n 
A 1 188 ARG 188 185 185 ARG ARG A . n 
A 1 189 VAL 189 186 186 VAL VAL A . n 
A 1 190 VAL 190 187 187 VAL VAL A . n 
A 1 191 GLY 191 188 188 GLY GLY A . n 
A 1 192 THR 192 189 189 THR THR A . n 
A 1 193 ALA 193 190 190 ALA ALA A . n 
A 1 194 GLY 194 191 191 GLY GLY A . n 
A 1 195 SER 195 192 192 SER SER A . n 
A 1 196 ALA 196 193 193 ALA ALA A . n 
A 1 197 GLY 197 194 194 GLY GLY A . n 
A 1 198 LYS 198 195 195 LYS LYS A . n 
A 1 199 ALA 199 196 196 ALA ALA A . n 
A 1 200 ARG 200 197 197 ARG ARG A . n 
A 1 201 TYR 201 198 198 TYR TYR A . n 
A 1 202 LEU 202 199 199 LEU LEU A . n 
A 1 203 SER 203 200 200 SER SER A . n 
A 1 204 GLN 204 201 201 GLN GLN A . n 
A 1 205 LEU 205 202 202 LEU LEU A . n 
A 1 206 GLY 206 203 203 GLY GLY A . n 
A 1 207 PHE 207 204 204 PHE PHE A . n 
A 1 208 ASP 208 205 205 ASP ASP A . n 
A 1 209 ALA 209 206 206 ALA ALA A . n 
A 1 210 VAL 210 207 207 VAL VAL A . n 
A 1 211 ILE 211 208 208 ILE ILE A . n 
A 1 212 ASP 212 209 209 ASP ASP A . n 
A 1 213 TYR 213 210 210 TYR TYR A . n 
A 1 214 LYS 214 211 211 LYS LYS A . n 
A 1 215 LEU 215 212 212 LEU LEU A . n 
A 1 216 ALA 216 213 213 ALA ALA A . n 
A 1 217 ASP 217 214 214 ASP ASP A . n 
A 1 218 ASP 218 215 215 ASP ASP A . n 
A 1 219 ALA 219 216 216 ALA ALA A . n 
A 1 220 ASP 220 217 217 ASP ASP A . n 
A 1 221 LYS 221 218 218 LYS LYS A . n 
A 1 222 MET 222 219 219 MET MET A . n 
A 1 223 ARG 223 220 220 ARG ARG A . n 
A 1 224 GLU 224 221 221 GLU GLU A . n 
A 1 225 ALA 225 222 222 ALA ALA A . n 
A 1 226 LEU 226 223 223 LEU LEU A . n 
A 1 227 ARG 227 224 224 ARG ARG A . n 
A 1 228 GLU 228 225 225 GLU GLU A . n 
A 1 229 ALA 229 226 226 ALA ALA A . n 
A 1 230 ALA 230 227 227 ALA ALA A . n 
A 1 231 PRO 231 228 228 PRO PRO A . n 
A 1 232 ASP 232 229 229 ASP ASP A . n 
A 1 233 GLY 233 230 230 GLY GLY A . n 
A 1 234 VAL 234 231 231 VAL VAL A . n 
A 1 235 ASP 235 232 232 ASP ASP A . n 
A 1 236 LYS 236 233 233 LYS LYS A . n 
A 1 237 TYR 237 234 234 TYR TYR A . n 
A 1 238 PHE 238 235 235 PHE PHE A . n 
A 1 239 ASP 239 236 236 ASP ASP A . n 
A 1 240 SER 240 237 237 SER SER A . n 
A 1 241 ILE 241 238 238 ILE ILE A . n 
A 1 242 GLY 242 239 239 GLY GLY A . n 
A 1 243 GLY 243 240 240 GLY GLY A . n 
A 1 244 SER 244 241 241 SER SER A . n 
A 1 245 VAL 245 242 242 VAL VAL A . n 
A 1 246 THR 246 243 243 THR THR A . n 
A 1 247 ASP 247 244 244 ASP ASP A . n 
A 1 248 ALA 248 245 245 ALA ALA A . n 
A 1 249 VAL 249 246 246 VAL VAL A . n 
A 1 250 PHE 250 247 247 PHE PHE A . n 
A 1 251 SER 251 248 248 SER SER A . n 
A 1 252 MET 252 249 249 MET MET A . n 
A 1 253 LEU 253 250 250 LEU LEU A . n 
A 1 254 ASN 254 251 251 ASN ASN A . n 
A 1 255 VAL 255 252 252 VAL VAL A . n 
A 1 256 GLY 256 253 253 GLY GLY A . n 
A 1 257 SER 257 254 254 SER SER A . n 
A 1 258 GLN 258 255 255 GLN GLN A . n 
A 1 259 VAL 259 256 256 VAL VAL A . n 
A 1 260 ALA 260 257 257 ALA ALA A . n 
A 1 261 VAL 261 258 258 VAL VAL A . n 
A 1 262 CYS 262 259 259 CYS CYS A . n 
A 1 263 TRP 263 260 260 TRP TRP A . n 
A 1 264 GLN 264 261 261 GLN GLN A . n 
A 1 265 TRP 265 262 262 TRP TRP A . n 
A 1 266 ALA 266 263 263 ALA ALA A . n 
A 1 267 THR 267 264 264 THR THR A . n 
A 1 268 GLN 268 265 265 GLN GLN A . n 
A 1 269 VAL 269 266 266 VAL VAL A . n 
A 1 270 GLN 270 267 267 GLN GLN A . n 
A 1 271 ARG 271 268 268 ARG ARG A . n 
A 1 272 ASP 272 269 269 ASP ASP A . n 
A 1 273 TYR 273 270 270 TYR TYR A . n 
A 1 274 HIS 274 271 271 HIS HIS A . n 
A 1 275 GLY 275 272 272 GLY GLY A . n 
A 1 276 PRO 276 273 273 PRO PRO A . n 
A 1 277 ARG 277 274 274 ARG ARG A . n 
A 1 278 LEU 278 275 275 LEU LEU A . n 
A 1 279 LEU 279 276 276 LEU LEU A . n 
A 1 280 PRO 280 277 277 PRO PRO A . n 
A 1 281 TYR 281 278 278 TYR TYR A . n 
A 1 282 ILE 282 279 279 ILE ILE A . n 
A 1 283 MET 283 280 280 MET MET A . n 
A 1 284 PHE 284 281 281 PHE PHE A . n 
A 1 285 PRO 285 282 282 PRO PRO A . n 
A 1 286 ARG 286 283 283 ARG ARG A . n 
A 1 287 ALA 287 284 284 ALA ALA A . n 
A 1 288 THR 288 285 285 THR THR A . n 
A 1 289 ILE 289 286 286 ILE ILE A . n 
A 1 290 ARG 290 287 287 ARG ARG A . n 
A 1 291 GLY 291 288 288 GLY GLY A . n 
A 1 292 ILE 292 289 289 ILE ILE A . n 
A 1 293 PHE 293 290 290 PHE PHE A . n 
A 1 294 SER 294 291 291 SER SER A . n 
A 1 295 LEU 295 292 292 LEU LEU A . n 
A 1 296 GLU 296 293 293 GLU GLU A . n 
A 1 297 TRP 297 294 294 TRP TRP A . n 
A 1 298 PHE 298 295 295 PHE PHE A . n 
A 1 299 THR 299 296 296 THR THR A . n 
A 1 300 GLU 300 297 297 GLU GLU A . n 
A 1 301 GLN 301 298 298 GLN GLN A . n 
A 1 302 ASN 302 299 299 ASN ASN A . n 
A 1 303 TRP 303 300 300 TRP TRP A . n 
A 1 304 SER 304 301 301 SER SER A . n 
A 1 305 ALA 305 302 302 ALA ALA A . n 
A 1 306 LEU 306 303 303 LEU LEU A . n 
A 1 307 HIS 307 304 304 HIS HIS A . n 
A 1 308 GLU 308 305 305 GLU GLU A . n 
A 1 309 GLU 309 306 306 GLU GLU A . n 
A 1 310 LEU 310 307 307 LEU LEU A . n 
A 1 311 GLY 311 308 308 GLY GLY A . n 
A 1 312 GLY 312 309 309 GLY GLY A . n 
A 1 313 LEU 313 310 310 LEU LEU A . n 
A 1 314 VAL 314 311 311 VAL VAL A . n 
A 1 315 ARG 315 312 312 ARG ARG A . n 
A 1 316 ARG 316 313 313 ARG ARG A . n 
A 1 317 GLN 317 314 314 GLN GLN A . n 
A 1 318 GLU 318 315 315 GLU GLU A . n 
A 1 319 LEU 319 316 316 LEU LEU A . n 
A 1 320 VAL 320 317 317 VAL VAL A . n 
A 1 321 ALA 321 318 318 ALA ALA A . n 
A 1 322 HIS 322 319 319 HIS HIS A . n 
A 1 323 GLU 323 320 320 GLU GLU A . n 
A 1 324 THR 324 321 321 THR THR A . n 
A 1 325 VAL 325 322 322 VAL VAL A . n 
A 1 326 GLN 326 323 323 GLN GLN A . n 
A 1 327 ASP 327 324 324 ASP ASP A . n 
A 1 328 GLY 328 325 325 GLY GLY A . n 
A 1 329 PHE 329 326 326 PHE PHE A . n 
A 1 330 GLU 330 327 327 GLU GLU A . n 
A 1 331 HIS 331 328 328 HIS HIS A . n 
A 1 332 ILE 332 329 329 ILE ILE A . n 
A 1 333 PRO 333 330 330 PRO PRO A . n 
A 1 334 ALA 334 331 331 ALA ALA A . n 
A 1 335 ALA 335 332 332 ALA ALA A . n 
A 1 336 TYR 336 333 333 TYR TYR A . n 
A 1 337 GLN 337 334 334 GLN GLN A . n 
A 1 338 THR 338 335 335 THR THR A . n 
A 1 339 LEU 339 336 336 LEU LEU A . n 
A 1 340 PHE 340 337 337 PHE PHE A . n 
A 1 341 SER 341 338 338 SER SER A . n 
A 1 342 ALA 342 339 339 ALA ALA A . n 
A 1 343 SER 343 340 340 SER SER A . n 
A 1 344 GLU 344 341 341 GLU GLU A . n 
A 1 345 SER 345 342 342 SER SER A . n 
A 1 346 ASN 346 343 343 ASN ASN A . n 
A 1 347 ARG 347 344 344 ARG ARG A . n 
A 1 348 GLY 348 345 345 GLY GLY A . n 
A 1 349 LYS 349 346 346 LYS LYS A . n 
A 1 350 VAL 350 347 347 VAL VAL A . n 
A 1 351 LEU 351 348 348 LEU LEU A . n 
A 1 352 VAL 352 349 349 VAL VAL A . n 
A 1 353 ARG 353 350 350 ARG ARG A . n 
A 1 354 VAL 354 351 351 VAL VAL A . n 
B 1 1   LEU 1   -2  -2  LEU LEU B . n 
B 1 2   GLY 2   -1  -1  GLY GLY B . n 
B 1 3   SER 3   0   0   SER SER B . n 
B 1 4   MET 4   1   1   MET MET B . n 
B 1 5   LYS 5   2   2   LYS LYS B . n 
B 1 6   THR 6   3   3   THR THR B . n 
B 1 7   GLU 7   4   4   GLU GLU B . n 
B 1 8   ARG 8   5   5   ARG ARG B . n 
B 1 9   TRP 9   6   6   TRP TRP B . n 
B 1 10  VAL 10  7   7   VAL VAL B . n 
B 1 11  VAL 11  8   8   VAL VAL B . n 
B 1 12  ARG 12  9   9   ARG ARG B . n 
B 1 13  GLU 13  10  10  GLU GLU B . n 
B 1 14  HIS 14  11  11  HIS HIS B . n 
B 1 15  VAL 15  12  12  VAL VAL B . n 
B 1 16  GLU 16  13  13  GLU GLU B . n 
B 1 17  GLY 17  14  14  GLY GLY B . n 
B 1 18  VAL 18  15  15  VAL VAL B . n 
B 1 19  PRO 19  16  16  PRO PRO B . n 
B 1 20  ASP 20  17  17  ASP ASP B . n 
B 1 21  ALA 21  18  18  ALA ALA B . n 
B 1 22  ALA 22  19  19  ALA ALA B . n 
B 1 23  ARG 23  20  20  ARG ARG B . n 
B 1 24  ILE 24  21  21  ILE ILE B . n 
B 1 25  TYR 25  22  22  TYR TYR B . n 
B 1 26  GLU 26  23  23  GLU GLU B . n 
B 1 27  LYS 27  24  24  LYS LYS B . n 
B 1 28  VAL 28  25  25  VAL VAL B . n 
B 1 29  GLU 29  26  26  GLU GLU B . n 
B 1 30  THR 30  27  27  THR THR B . n 
B 1 31  GLU 31  28  28  GLU GLU B . n 
B 1 32  LEU 32  29  29  LEU LEU B . n 
B 1 33  ASN 33  30  30  ASN ASN B . n 
B 1 34  THR 34  31  31  THR THR B . n 
B 1 35  ARG 35  32  32  ARG ARG B . n 
B 1 36  LEU 36  33  33  LEU LEU B . n 
B 1 37  GLY 37  34  34  GLY GLY B . n 
B 1 38  GLU 38  35  35  GLU GLU B . n 
B 1 39  GLU 39  36  36  GLU GLU B . n 
B 1 40  GLN 40  37  37  GLN GLN B . n 
B 1 41  MET 41  38  38  MET MET B . n 
B 1 42  LEU 42  39  39  LEU LEU B . n 
B 1 43  LEU 43  40  40  LEU LEU B . n 
B 1 44  LYS 44  41  41  LYS LYS B . n 
B 1 45  THR 45  42  42  THR THR B . n 
B 1 46  LEU 46  43  43  LEU LEU B . n 
B 1 47  TYR 47  44  44  TYR TYR B . n 
B 1 48  VAL 48  45  45  VAL VAL B . n 
B 1 49  SER 49  46  46  SER SER B . n 
B 1 50  VAL 50  47  47  VAL VAL B . n 
B 1 51  ASP 51  48  48  ASP ASP B . n 
B 1 52  PRO 52  49  49  PRO PRO B . n 
B 1 53  TYR 53  50  50  TYR TYR B . n 
B 1 54  LEU 54  51  51  LEU LEU B . n 
B 1 55  GLN 55  52  52  GLN GLN B . n 
B 1 56  GLY 56  53  53  GLY GLY B . n 
B 1 57  ILE 57  54  54  ILE ILE B . n 
B 1 58  CYS 58  55  55  CYS CYS B . n 
B 1 59  LEU 59  56  56  LEU LEU B . n 
B 1 60  ASP 60  57  57  ASP ASP B . n 
B 1 61  THR 61  58  58  THR THR B . n 
B 1 62  PRO 62  59  59  PRO PRO B . n 
B 1 63  ILE 63  60  60  ILE ILE B . n 
B 1 64  GLY 64  61  61  GLY GLY B . n 
B 1 65  ASP 65  62  62  ASP ASP B . n 
B 1 66  HIS 66  63  63  HIS HIS B . n 
B 1 67  MET 67  64  64  MET MET B . n 
B 1 68  GLY 68  65  65  GLY GLY B . n 
B 1 69  ALA 69  66  66  ALA ALA B . n 
B 1 70  ASP 70  67  67  ASP ASP B . n 
B 1 71  SER 71  68  68  SER SER B . n 
B 1 72  ILE 72  69  69  ILE ILE B . n 
B 1 73  MET 73  70  70  MET MET B . n 
B 1 74  GLN 74  71  71  GLN GLN B . n 
B 1 75  VAL 75  72  72  VAL VAL B . n 
B 1 76  LEU 76  73  73  LEU LEU B . n 
B 1 77  ASP 77  74  74  ASP ASP B . n 
B 1 78  ALA 78  75  75  ALA ALA B . n 
B 1 79  GLY 79  76  76  GLY GLY B . n 
B 1 80  PRO 80  77  77  PRO PRO B . n 
B 1 81  ASN 81  78  78  ASN ASN B . n 
B 1 82  ALA 82  79  79  ALA ALA B . n 
B 1 83  PRO 83  80  80  PRO PRO B . n 
B 1 84  PHE 84  81  81  PHE PHE B . n 
B 1 85  ARG 85  82  82  ARG ARG B . n 
B 1 86  PRO 86  83  83  PRO PRO B . n 
B 1 87  GLY 87  84  84  GLY GLY B . n 
B 1 88  ASP 88  85  85  ASP ASP B . n 
B 1 89  LEU 89  86  86  LEU LEU B . n 
B 1 90  VAL 90  87  87  VAL VAL B . n 
B 1 91  GLN 91  88  88  GLN GLN B . n 
B 1 92  GLY 92  89  89  GLY GLY B . n 
B 1 93  PHE 93  90  90  PHE PHE B . n 
B 1 94  GLY 94  91  91  GLY GLY B . n 
B 1 95  GLY 95  92  92  GLY GLY B . n 
B 1 96  TRP 96  93  93  TRP TRP B . n 
B 1 97  ARG 97  94  94  ARG ARG B . n 
B 1 98  THR 98  95  95  THR THR B . n 
B 1 99  HIS 99  96  96  HIS HIS B . n 
B 1 100 LEU 100 97  97  LEU LEU B . n 
B 1 101 VAL 101 98  98  VAL VAL B . n 
B 1 102 SER 102 99  99  SER SER B . n 
B 1 103 ASP 103 100 100 ASP ASP B . n 
B 1 104 GLY 104 101 101 GLY GLY B . n 
B 1 105 LYS 105 102 102 LYS LYS B . n 
B 1 106 PRO 106 103 103 PRO PRO B . n 
B 1 107 LYS 107 104 104 LYS LYS B . n 
B 1 108 LEU 108 105 105 LEU LEU B . n 
B 1 109 TRP 109 106 106 TRP TRP B . n 
B 1 110 GLN 110 107 107 GLN GLN B . n 
B 1 111 THR 111 108 108 THR THR B . n 
B 1 112 GLY 112 109 109 GLY GLY B . n 
B 1 113 THR 113 110 110 THR THR B . n 
B 1 114 PHE 114 111 111 PHE PHE B . n 
B 1 115 PRO 115 112 112 PRO PRO B . n 
B 1 116 MET 116 113 113 MET MET B . n 
B 1 117 VAL 117 114 114 VAL VAL B . n 
B 1 118 PHE 118 115 115 PHE PHE B . n 
B 1 119 PRO 119 116 116 PRO PRO B . n 
B 1 120 ALA 120 117 117 ALA ALA B . n 
B 1 121 TYR 121 118 118 TYR TYR B . n 
B 1 122 ARG 122 119 119 ARG ARG B . n 
B 1 123 LYS 123 120 120 LYS LYS B . n 
B 1 124 LEU 124 121 121 LEU LEU B . n 
B 1 125 ASP 125 122 122 ASP ASP B . n 
B 1 126 LEU 126 123 123 LEU LEU B . n 
B 1 127 ARG 127 124 124 ARG ARG B . n 
B 1 128 HIS 128 125 125 HIS HIS B . n 
B 1 129 TYR 129 126 126 TYR TYR B . n 
B 1 130 ASP 130 127 127 ASP ASP B . n 
B 1 131 ASP 131 128 128 ASP ASP B . n 
B 1 132 ALA 132 129 129 ALA ALA B . n 
B 1 133 LEU 133 130 130 LEU LEU B . n 
B 1 134 PRO 134 131 131 PRO PRO B . n 
B 1 135 LEU 135 132 132 LEU LEU B . n 
B 1 136 SER 136 133 133 SER SER B . n 
B 1 137 THR 137 134 134 THR THR B . n 
B 1 138 ALA 138 135 135 ALA ALA B . n 
B 1 139 LEU 139 136 136 LEU LEU B . n 
B 1 140 GLY 140 137 137 GLY GLY B . n 
B 1 141 VAL 141 138 138 VAL VAL B . n 
B 1 142 MET 142 139 139 MET MET B . n 
B 1 143 GLY 143 140 140 GLY GLY B . n 
B 1 144 GLY 144 141 141 GLY GLY B . n 
B 1 145 PRO 145 142 142 PRO PRO B . n 
B 1 146 GLY 146 143 143 GLY GLY B . n 
B 1 147 MET 147 144 144 MET MET B . n 
B 1 148 THR 148 145 145 THR THR B . n 
B 1 149 ALA 149 146 146 ALA ALA B . n 
B 1 150 TRP 150 147 147 TRP TRP B . n 
B 1 151 GLY 151 148 148 GLY GLY B . n 
B 1 152 THR 152 149 149 THR THR B . n 
B 1 153 MET 153 150 150 MET MET B . n 
B 1 154 THR 154 151 151 THR THR B . n 
B 1 155 LYS 155 152 152 LYS LYS B . n 
B 1 156 PHE 156 153 153 PHE PHE B . n 
B 1 157 MET 157 154 154 MET MET B . n 
B 1 158 GLN 158 155 155 GLN GLN B . n 
B 1 159 VAL 159 156 156 VAL VAL B . n 
B 1 160 ARG 160 157 157 ARG ARG B . n 
B 1 161 PRO 161 158 158 PRO PRO B . n 
B 1 162 GLY 162 159 159 GLY GLY B . n 
B 1 163 ASP 163 160 160 ASP ASP B . n 
B 1 164 THR 164 161 161 THR THR B . n 
B 1 165 VAL 165 162 162 VAL VAL B . n 
B 1 166 VAL 166 163 163 VAL VAL B . n 
B 1 167 VAL 167 164 164 VAL VAL B . n 
B 1 168 SER 168 165 165 SER SER B . n 
B 1 169 GLY 169 166 166 GLY GLY B . n 
B 1 170 ALA 170 167 167 ALA ALA B . n 
B 1 171 SER 171 168 168 SER SER B . n 
B 1 172 GLY 172 169 169 GLY GLY B . n 
B 1 173 MET 173 170 170 MET MET B . n 
B 1 174 ILE 174 171 171 ILE ILE B . n 
B 1 175 GLY 175 172 172 GLY GLY B . n 
B 1 176 THR 176 173 173 THR THR B . n 
B 1 177 LEU 177 174 174 LEU LEU B . n 
B 1 178 VAL 178 175 175 VAL VAL B . n 
B 1 179 GLY 179 176 176 GLY GLY B . n 
B 1 180 GLN 180 177 177 GLN GLN B . n 
B 1 181 MET 181 178 178 MET MET B . n 
B 1 182 ALA 182 179 179 ALA ALA B . n 
B 1 183 LYS 183 180 180 LYS LYS B . n 
B 1 184 ARG 184 181 181 ARG ARG B . n 
B 1 185 ALA 185 182 182 ALA ALA B . n 
B 1 186 GLY 186 183 183 GLY GLY B . n 
B 1 187 ALA 187 184 184 ALA ALA B . n 
B 1 188 ARG 188 185 185 ARG ARG B . n 
B 1 189 VAL 189 186 186 VAL VAL B . n 
B 1 190 VAL 190 187 187 VAL VAL B . n 
B 1 191 GLY 191 188 188 GLY GLY B . n 
B 1 192 THR 192 189 189 THR THR B . n 
B 1 193 ALA 193 190 190 ALA ALA B . n 
B 1 194 GLY 194 191 191 GLY GLY B . n 
B 1 195 SER 195 192 192 SER SER B . n 
B 1 196 ALA 196 193 193 ALA ALA B . n 
B 1 197 GLY 197 194 194 GLY GLY B . n 
B 1 198 LYS 198 195 195 LYS LYS B . n 
B 1 199 ALA 199 196 196 ALA ALA B . n 
B 1 200 ARG 200 197 197 ARG ARG B . n 
B 1 201 TYR 201 198 198 TYR TYR B . n 
B 1 202 LEU 202 199 199 LEU LEU B . n 
B 1 203 SER 203 200 200 SER SER B . n 
B 1 204 GLN 204 201 201 GLN GLN B . n 
B 1 205 LEU 205 202 202 LEU LEU B . n 
B 1 206 GLY 206 203 203 GLY GLY B . n 
B 1 207 PHE 207 204 204 PHE PHE B . n 
B 1 208 ASP 208 205 205 ASP ASP B . n 
B 1 209 ALA 209 206 206 ALA ALA B . n 
B 1 210 VAL 210 207 207 VAL VAL B . n 
B 1 211 ILE 211 208 208 ILE ILE B . n 
B 1 212 ASP 212 209 209 ASP ASP B . n 
B 1 213 TYR 213 210 210 TYR TYR B . n 
B 1 214 LYS 214 211 211 LYS LYS B . n 
B 1 215 LEU 215 212 212 LEU LEU B . n 
B 1 216 ALA 216 213 213 ALA ALA B . n 
B 1 217 ASP 217 214 214 ASP ASP B . n 
B 1 218 ASP 218 215 215 ASP ASP B . n 
B 1 219 ALA 219 216 216 ALA ALA B . n 
B 1 220 ASP 220 217 217 ASP ASP B . n 
B 1 221 LYS 221 218 218 LYS LYS B . n 
B 1 222 MET 222 219 219 MET MET B . n 
B 1 223 ARG 223 220 220 ARG ARG B . n 
B 1 224 GLU 224 221 221 GLU GLU B . n 
B 1 225 ALA 225 222 222 ALA ALA B . n 
B 1 226 LEU 226 223 223 LEU LEU B . n 
B 1 227 ARG 227 224 224 ARG ARG B . n 
B 1 228 GLU 228 225 225 GLU GLU B . n 
B 1 229 ALA 229 226 226 ALA ALA B . n 
B 1 230 ALA 230 227 227 ALA ALA B . n 
B 1 231 PRO 231 228 228 PRO PRO B . n 
B 1 232 ASP 232 229 229 ASP ASP B . n 
B 1 233 GLY 233 230 230 GLY GLY B . n 
B 1 234 VAL 234 231 231 VAL VAL B . n 
B 1 235 ASP 235 232 232 ASP ASP B . n 
B 1 236 LYS 236 233 233 LYS LYS B . n 
B 1 237 TYR 237 234 234 TYR TYR B . n 
B 1 238 PHE 238 235 235 PHE PHE B . n 
B 1 239 ASP 239 236 236 ASP ASP B . n 
B 1 240 SER 240 237 237 SER SER B . n 
B 1 241 ILE 241 238 238 ILE ILE B . n 
B 1 242 GLY 242 239 239 GLY GLY B . n 
B 1 243 GLY 243 240 240 GLY GLY B . n 
B 1 244 SER 244 241 241 SER SER B . n 
B 1 245 VAL 245 242 242 VAL VAL B . n 
B 1 246 THR 246 243 243 THR THR B . n 
B 1 247 ASP 247 244 244 ASP ASP B . n 
B 1 248 ALA 248 245 245 ALA ALA B . n 
B 1 249 VAL 249 246 246 VAL VAL B . n 
B 1 250 PHE 250 247 247 PHE PHE B . n 
B 1 251 SER 251 248 248 SER SER B . n 
B 1 252 MET 252 249 249 MET MET B . n 
B 1 253 LEU 253 250 250 LEU LEU B . n 
B 1 254 ASN 254 251 251 ASN ASN B . n 
B 1 255 VAL 255 252 252 VAL VAL B . n 
B 1 256 GLY 256 253 253 GLY GLY B . n 
B 1 257 SER 257 254 254 SER SER B . n 
B 1 258 GLN 258 255 255 GLN GLN B . n 
B 1 259 VAL 259 256 256 VAL VAL B . n 
B 1 260 ALA 260 257 257 ALA ALA B . n 
B 1 261 VAL 261 258 258 VAL VAL B . n 
B 1 262 CYS 262 259 259 CYS CYS B . n 
B 1 263 TRP 263 260 260 TRP TRP B . n 
B 1 264 GLN 264 261 261 GLN GLN B . n 
B 1 265 TRP 265 262 262 TRP TRP B . n 
B 1 266 ALA 266 263 263 ALA ALA B . n 
B 1 267 THR 267 264 264 THR THR B . n 
B 1 268 GLN 268 265 265 GLN GLN B . n 
B 1 269 VAL 269 266 266 VAL VAL B . n 
B 1 270 GLN 270 267 267 GLN GLN B . n 
B 1 271 ARG 271 268 268 ARG ARG B . n 
B 1 272 ASP 272 269 269 ASP ASP B . n 
B 1 273 TYR 273 270 270 TYR TYR B . n 
B 1 274 HIS 274 271 271 HIS HIS B . n 
B 1 275 GLY 275 272 272 GLY GLY B . n 
B 1 276 PRO 276 273 273 PRO PRO B . n 
B 1 277 ARG 277 274 274 ARG ARG B . n 
B 1 278 LEU 278 275 275 LEU LEU B . n 
B 1 279 LEU 279 276 276 LEU LEU B . n 
B 1 280 PRO 280 277 277 PRO PRO B . n 
B 1 281 TYR 281 278 278 TYR TYR B . n 
B 1 282 ILE 282 279 279 ILE ILE B . n 
B 1 283 MET 283 280 280 MET MET B . n 
B 1 284 PHE 284 281 281 PHE PHE B . n 
B 1 285 PRO 285 282 282 PRO PRO B . n 
B 1 286 ARG 286 283 283 ARG ARG B . n 
B 1 287 ALA 287 284 284 ALA ALA B . n 
B 1 288 THR 288 285 285 THR THR B . n 
B 1 289 ILE 289 286 286 ILE ILE B . n 
B 1 290 ARG 290 287 287 ARG ARG B . n 
B 1 291 GLY 291 288 288 GLY GLY B . n 
B 1 292 ILE 292 289 289 ILE ILE B . n 
B 1 293 PHE 293 290 290 PHE PHE B . n 
B 1 294 SER 294 291 291 SER SER B . n 
B 1 295 LEU 295 292 292 LEU LEU B . n 
B 1 296 GLU 296 293 293 GLU GLU B . n 
B 1 297 TRP 297 294 294 TRP TRP B . n 
B 1 298 PHE 298 295 295 PHE PHE B . n 
B 1 299 THR 299 296 296 THR THR B . n 
B 1 300 GLU 300 297 297 GLU GLU B . n 
B 1 301 GLN 301 298 298 GLN GLN B . n 
B 1 302 ASN 302 299 299 ASN ASN B . n 
B 1 303 TRP 303 300 300 TRP TRP B . n 
B 1 304 SER 304 301 301 SER SER B . n 
B 1 305 ALA 305 302 302 ALA ALA B . n 
B 1 306 LEU 306 303 303 LEU LEU B . n 
B 1 307 HIS 307 304 304 HIS HIS B . n 
B 1 308 GLU 308 305 305 GLU GLU B . n 
B 1 309 GLU 309 306 306 GLU GLU B . n 
B 1 310 LEU 310 307 307 LEU LEU B . n 
B 1 311 GLY 311 308 308 GLY GLY B . n 
B 1 312 GLY 312 309 309 GLY GLY B . n 
B 1 313 LEU 313 310 310 LEU LEU B . n 
B 1 314 VAL 314 311 311 VAL VAL B . n 
B 1 315 ARG 315 312 312 ARG ARG B . n 
B 1 316 ARG 316 313 313 ARG ARG B . n 
B 1 317 GLN 317 314 314 GLN GLN B . n 
B 1 318 GLU 318 315 315 GLU GLU B . n 
B 1 319 LEU 319 316 316 LEU LEU B . n 
B 1 320 VAL 320 317 317 VAL VAL B . n 
B 1 321 ALA 321 318 318 ALA ALA B . n 
B 1 322 HIS 322 319 319 HIS HIS B . n 
B 1 323 GLU 323 320 320 GLU GLU B . n 
B 1 324 THR 324 321 321 THR THR B . n 
B 1 325 VAL 325 322 322 VAL VAL B . n 
B 1 326 GLN 326 323 323 GLN GLN B . n 
B 1 327 ASP 327 324 324 ASP ASP B . n 
B 1 328 GLY 328 325 325 GLY GLY B . n 
B 1 329 PHE 329 326 326 PHE PHE B . n 
B 1 330 GLU 330 327 327 GLU GLU B . n 
B 1 331 HIS 331 328 328 HIS HIS B . n 
B 1 332 ILE 332 329 329 ILE ILE B . n 
B 1 333 PRO 333 330 330 PRO PRO B . n 
B 1 334 ALA 334 331 331 ALA ALA B . n 
B 1 335 ALA 335 332 332 ALA ALA B . n 
B 1 336 TYR 336 333 333 TYR TYR B . n 
B 1 337 GLN 337 334 334 GLN GLN B . n 
B 1 338 THR 338 335 335 THR THR B . n 
B 1 339 LEU 339 336 336 LEU LEU B . n 
B 1 340 PHE 340 337 337 PHE PHE B . n 
B 1 341 SER 341 338 338 SER SER B . n 
B 1 342 ALA 342 339 339 ALA ALA B . n 
B 1 343 SER 343 340 340 SER SER B . n 
B 1 344 GLU 344 341 341 GLU GLU B . n 
B 1 345 SER 345 342 342 SER SER B . n 
B 1 346 ASN 346 343 343 ASN ASN B . n 
B 1 347 ARG 347 344 344 ARG ARG B . n 
B 1 348 GLY 348 345 345 GLY GLY B . n 
B 1 349 LYS 349 346 346 LYS LYS B . n 
B 1 350 VAL 350 347 347 VAL VAL B . n 
B 1 351 LEU 351 348 348 LEU LEU B . n 
B 1 352 VAL 352 349 349 VAL VAL B . n 
B 1 353 ARG 353 350 350 ARG ARG B . n 
B 1 354 VAL 354 351 351 VAL VAL B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NAP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NAP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 NAP 1 501 501 NAP NAP A . 
D 2 NAP 1 501 501 NAP NAP B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX      ? ? ? '(???)' 1 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? HKL-3000    ? ? ? .       2 
? 'data extraction' ? ? ? ? ? ? ? ? ? ? ? PDB_EXTRACT ? ? ? .       3 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER      ? ? ? .       4 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? HKL-3000    ? ? ? .       5 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JLY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     90.037 
_cell.length_a_esd                 ? 
_cell.length_b                     90.037 
_cell.length_b_esd                 ? 
_cell.length_c                     203.812 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JLY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                92 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 41 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JLY 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.65 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          53.61 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              9.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;PEG3350,sodium chloride,bis-tris
hydrochloride
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-07-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    Si111 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97915 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97915 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9JLY 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.11 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     15720 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                12.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          14.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.193 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.11 
_reflns_shell.d_res_low                                     3.21 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2837 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.924 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9JLY 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.11 
_refine.ls_d_res_low                             18.00 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     15562 
_refine.ls_number_reflns_R_free                  1557 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.41 
_refine.ls_percent_reflns_R_free                 10.01 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1882 
_refine.ls_R_factor_R_free                       0.2507 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1813 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 25.91 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.39 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.11 
_refine_hist.d_res_low                        18.00 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               5568 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5472 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         96 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  ? 5704 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.117  ? 7756 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 16.366 ? 2046 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.060  ? 842  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.009  ? 994  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.11 3.21  . . 136 1213 97.00  . . . . 0.2647 . . . . . . . . . . . 0.3520 
'X-RAY DIFFRACTION' 3.21 3.33  . . 135 1232 100.00 . . . . 0.2232 . . . . . . . . . . . 0.2711 
'X-RAY DIFFRACTION' 3.33 3.46  . . 139 1249 99.00  . . . . 0.2120 . . . . . . . . . . . 0.2754 
'X-RAY DIFFRACTION' 3.46 3.61  . . 140 1258 100.00 . . . . 0.2042 . . . . . . . . . . . 0.3113 
'X-RAY DIFFRACTION' 3.61 3.80  . . 140 1252 99.00  . . . . 0.1893 . . . . . . . . . . . 0.2737 
'X-RAY DIFFRACTION' 3.80 4.04  . . 138 1252 99.00  . . . . 0.1844 . . . . . . . . . . . 0.2541 
'X-RAY DIFFRACTION' 4.04 4.35  . . 141 1269 100.00 . . . . 0.1626 . . . . . . . . . . . 0.2403 
'X-RAY DIFFRACTION' 4.35 4.78  . . 143 1287 100.00 . . . . 0.1553 . . . . . . . . . . . 0.2410 
'X-RAY DIFFRACTION' 4.78 5.45  . . 143 1285 100.00 . . . . 0.1661 . . . . . . . . . . . 0.2305 
'X-RAY DIFFRACTION' 5.45 6.80  . . 146 1318 100.00 . . . . 0.1922 . . . . . . . . . . . 0.2676 
'X-RAY DIFFRACTION' 6.80 18.00 . . 156 1390 99.00  . . . . 0.1624 . . . . . . . . . . . 0.1990 
# 
_struct.entry_id                     9JLY 
_struct.title                        'NADP-dependent oxidoreductase complexed with NADP' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JLY 
_struct_keywords.text            'alcohol dehydrogenase, complex, BIOSYNTHETIC PROTEIN' 
_struct_keywords.pdbx_keywords   'BIOSYNTHETIC PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    C3PTT2_LYSEN 
_struct_ref.pdbx_db_accession          C3PTT2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKTERWVVREHVEGVPDAARIYEKVETELNTRLGEEQMLLKTLYVSVDPYLQGICLDTPIGDHMGADSIMQVLDAGPNAP
FRPGDLVQGFGGWRTHLVSDGKPKLWQTGTFPMVFPAYRKLDLRHYDDALPLSTALGVMGGPGMTAWGTMTKFMQVRPGD
TVVVSGASGMIGTLVGQMAKRAGARVVGTAGSAGKARYLSQLGFDAVIDYKLADDADKMREALREAAPDGVDKYFDSIGG
SVTDAVFSMLNVGSQVAVCWQWATQVQRDYHGPRLLPYIMFPRATIRGIFSLEWFTEQNWSALHEELGGLVRRQELVAHE
TVQDGFEHIPAAYQTLFSASESNRGKVLVRV
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JLY A 4 ? 354 ? C3PTT2 1 ? 351 ? 1 351 
2 1 9JLY B 4 ? 354 ? C3PTT2 1 ? 351 ? 1 351 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9JLY LEU A 1 ? UNP C3PTT2 ? ? 'expression tag' -2 1 
1 9JLY GLY A 2 ? UNP C3PTT2 ? ? 'expression tag' -1 2 
1 9JLY SER A 3 ? UNP C3PTT2 ? ? 'expression tag' 0  3 
2 9JLY LEU B 1 ? UNP C3PTT2 ? ? 'expression tag' -2 4 
2 9JLY GLY B 2 ? UNP C3PTT2 ? ? 'expression tag' -1 5 
2 9JLY SER B 3 ? UNP C3PTT2 ? ? 'expression tag' 0  6 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 5710  ? 
1 MORE         -30   ? 
1 'SSA (A^2)'  28620 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 20  ? ILE A 24  ? ASP A 17  ILE A 21  1 ? 5  
HELX_P HELX_P2  AA2 TYR A 53  ? THR A 61  ? TYR A 50  THR A 58  1 ? 9  
HELX_P HELX_P3  AA3 ASP A 125 ? TYR A 129 ? ASP A 122 TYR A 126 5 ? 5  
HELX_P HELX_P4  AA4 PRO A 134 ? GLY A 140 ? PRO A 131 GLY A 137 5 ? 7  
HELX_P HELX_P5  AA5 GLY A 143 ? PHE A 156 ? GLY A 140 PHE A 153 1 ? 14 
HELX_P HELX_P6  AA6 GLY A 172 ? ALA A 185 ? GLY A 169 ALA A 182 1 ? 14 
HELX_P HELX_P7  AA7 SER A 195 ? GLY A 206 ? SER A 192 GLY A 203 1 ? 12 
HELX_P HELX_P8  AA8 ASP A 218 ? ALA A 230 ? ASP A 215 ALA A 227 1 ? 13 
HELX_P HELX_P9  AA9 GLY A 242 ? SER A 251 ? GLY A 239 SER A 248 1 ? 10 
HELX_P HELX_P10 AB1 GLN A 264 ? VAL A 269 ? GLN A 261 VAL A 266 1 ? 6  
HELX_P HELX_P11 AB2 LEU A 278 ? MET A 283 ? LEU A 275 MET A 280 5 ? 6  
HELX_P HELX_P12 AB3 PHE A 293 ? PHE A 298 ? PHE A 290 PHE A 295 5 ? 6  
HELX_P HELX_P13 AB4 THR A 299 ? ARG A 316 ? THR A 296 ARG A 313 1 ? 18 
HELX_P HELX_P14 AB5 HIS A 331 ? THR A 338 ? HIS A 328 THR A 335 1 ? 8  
HELX_P HELX_P15 AB6 ASP B 20  ? ILE B 24  ? ASP B 17  ILE B 21  1 ? 5  
HELX_P HELX_P16 AB7 TYR B 53  ? THR B 61  ? TYR B 50  THR B 58  1 ? 9  
HELX_P HELX_P17 AB8 ASP B 125 ? TYR B 129 ? ASP B 122 TYR B 126 5 ? 5  
HELX_P HELX_P18 AB9 PRO B 134 ? GLY B 140 ? PRO B 131 GLY B 137 5 ? 7  
HELX_P HELX_P19 AC1 GLY B 143 ? PHE B 156 ? GLY B 140 PHE B 153 1 ? 14 
HELX_P HELX_P20 AC2 GLY B 172 ? ALA B 185 ? GLY B 169 ALA B 182 1 ? 14 
HELX_P HELX_P21 AC3 SER B 195 ? GLN B 204 ? SER B 192 GLN B 201 1 ? 10 
HELX_P HELX_P22 AC4 ASP B 218 ? ALA B 230 ? ASP B 215 ALA B 227 1 ? 13 
HELX_P HELX_P23 AC5 GLY B 242 ? SER B 251 ? GLY B 239 SER B 248 1 ? 10 
HELX_P HELX_P24 AC6 GLN B 264 ? VAL B 269 ? GLN B 261 VAL B 266 1 ? 6  
HELX_P HELX_P25 AC7 LEU B 278 ? MET B 283 ? LEU B 275 MET B 280 5 ? 6  
HELX_P HELX_P26 AC8 PHE B 293 ? PHE B 298 ? PHE B 290 PHE B 295 5 ? 6  
HELX_P HELX_P27 AC9 THR B 299 ? ARG B 316 ? THR B 296 ARG B 313 1 ? 18 
HELX_P HELX_P28 AD1 HIS B 331 ? SER B 341 ? HIS B 328 SER B 338 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2  ? 
AA2 ? 5  ? 
AA3 ? 4  ? 
AA4 ? 2  ? 
AA5 ? 12 ? 
AA6 ? 2  ? 
AA7 ? 2  ? 
AA8 ? 5  ? 
AA9 ? 4  ? 
AB1 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? parallel      
AA4 1  2  ? anti-parallel 
AA5 1  2  ? parallel      
AA5 2  3  ? parallel      
AA5 3  4  ? parallel      
AA5 4  5  ? parallel      
AA5 5  6  ? parallel      
AA5 6  7  ? anti-parallel 
AA5 7  8  ? parallel      
AA5 8  9  ? parallel      
AA5 9  10 ? parallel      
AA5 10 11 ? parallel      
AA5 11 12 ? parallel      
AA6 1  2  ? anti-parallel 
AA7 1  2  ? anti-parallel 
AA8 1  2  ? anti-parallel 
AA8 2  3  ? anti-parallel 
AA8 3  4  ? anti-parallel 
AA8 4  5  ? anti-parallel 
AA9 1  2  ? anti-parallel 
AA9 2  3  ? anti-parallel 
AA9 3  4  ? parallel      
AB1 1  2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  SER A 3   ? VAL A 11  ? SER A 0   VAL A 8   
AA1 2  TYR A 25  ? ASN A 33  ? TYR A 22  ASN A 30  
AA2 1  HIS A 99  ? SER A 102 ? HIS A 96  SER A 99  
AA2 2  MET A 41  ? VAL A 50  ? MET A 38  VAL A 47  
AA2 3  SER A 71  ? ALA A 78  ? SER A 68  ALA A 75  
AA2 4  LEU A 89  ? GLY A 92  ? LEU A 86  GLY A 89  
AA2 5  ARG A 122 ? LEU A 124 ? ARG A 119 LEU A 121 
AA3 1  HIS A 99  ? SER A 102 ? HIS A 96  SER A 99  
AA3 2  MET A 41  ? VAL A 50  ? MET A 38  VAL A 47  
AA3 3  LYS A 349 ? ARG A 353 ? LYS A 346 ARG A 350 
AA3 4  GLU A 323 ? ASP A 327 ? GLU A 320 ASP A 324 
AA4 1  LEU A 108 ? TRP A 109 ? LEU A 105 TRP A 106 
AA4 2  MET A 116 ? VAL A 117 ? MET A 113 VAL A 114 
AA5 1  ALA A 209 ? ASP A 212 ? ALA A 206 ASP A 209 
AA5 2  ARG A 188 ? ALA A 193 ? ARG A 185 ALA A 190 
AA5 3  THR A 164 ? VAL A 167 ? THR A 161 VAL A 164 
AA5 4  VAL A 234 ? ASP A 239 ? VAL A 231 ASP A 236 
AA5 5  LEU A 253 ? VAL A 261 ? LEU A 250 VAL A 258 
AA5 6  THR A 288 ? GLY A 291 ? THR A 285 GLY A 288 
AA5 7  THR B 288 ? GLY B 291 ? THR B 285 GLY B 288 
AA5 8  LEU B 253 ? VAL B 261 ? LEU B 250 VAL B 258 
AA5 9  VAL B 234 ? ASP B 239 ? VAL B 231 ASP B 236 
AA5 10 THR B 164 ? VAL B 167 ? THR B 161 VAL B 164 
AA5 11 ARG B 188 ? ALA B 193 ? ARG B 185 ALA B 190 
AA5 12 ALA B 209 ? ASP B 212 ? ALA B 206 ASP B 209 
AA6 1  HIS A 274 ? PRO A 276 ? HIS A 271 PRO A 273 
AA6 2  HIS B 274 ? PRO B 276 ? HIS B 271 PRO B 273 
AA7 1  SER B 3   ? VAL B 11  ? SER B 0   VAL B 8   
AA7 2  TYR B 25  ? ASN B 33  ? TYR B 22  ASN B 30  
AA8 1  HIS B 99  ? SER B 102 ? HIS B 96  SER B 99  
AA8 2  MET B 41  ? SER B 49  ? MET B 38  SER B 46  
AA8 3  SER B 71  ? ALA B 78  ? SER B 68  ALA B 75  
AA8 4  LEU B 89  ? GLY B 92  ? LEU B 86  GLY B 89  
AA8 5  ARG B 122 ? LEU B 124 ? ARG B 119 LEU B 121 
AA9 1  HIS B 99  ? SER B 102 ? HIS B 96  SER B 99  
AA9 2  MET B 41  ? SER B 49  ? MET B 38  SER B 46  
AA9 3  LYS B 349 ? ARG B 353 ? LYS B 346 ARG B 350 
AA9 4  GLU B 323 ? ASP B 327 ? GLU B 320 ASP B 324 
AB1 1  LEU B 108 ? TRP B 109 ? LEU B 105 TRP B 106 
AB1 2  MET B 116 ? VAL B 117 ? MET B 113 VAL B 114 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N THR A 6   ? N THR A 3   O THR A 30  ? O THR A 27  
AA2 1  2  O LEU A 100 ? O LEU A 97  N LEU A 43  ? N LEU A 40  
AA2 2  3  N LEU A 46  ? N LEU A 43  O ILE A 72  ? O ILE A 69  
AA2 3  4  N SER A 71  ? N SER A 68  O GLY A 92  ? O GLY A 89  
AA2 4  5  N LEU A 89  ? N LEU A 86  O LEU A 124 ? O LEU A 121 
AA3 1  2  O LEU A 100 ? O LEU A 97  N LEU A 43  ? N LEU A 40  
AA3 2  3  N VAL A 48  ? N VAL A 45  O VAL A 352 ? O VAL A 349 
AA3 3  4  O LYS A 349 ? O LYS A 346 N THR A 324 ? N THR A 321 
AA4 1  2  N TRP A 109 ? N TRP A 106 O MET A 116 ? O MET A 113 
AA5 1  2  O ALA A 209 ? O ALA A 206 N GLY A 191 ? N GLY A 188 
AA5 2  3  O ARG A 188 ? O ARG A 185 N VAL A 165 ? N VAL A 162 
AA5 3  4  N VAL A 166 ? N VAL A 163 O PHE A 238 ? O PHE A 235 
AA5 4  5  N VAL A 234 ? N VAL A 231 O ASN A 254 ? O ASN A 251 
AA5 5  6  N SER A 257 ? N SER A 254 O THR A 288 ? O THR A 285 
AA5 6  7  N ILE A 289 ? N ILE A 286 O ILE B 289 ? O ILE B 286 
AA5 7  8  O THR B 288 ? O THR B 285 N SER B 257 ? N SER B 254 
AA5 8  9  O ASN B 254 ? O ASN B 251 N VAL B 234 ? N VAL B 231 
AA5 9  10 O LYS B 236 ? O LYS B 233 N VAL B 166 ? N VAL B 163 
AA5 10 11 N VAL B 167 ? N VAL B 164 O VAL B 190 ? O VAL B 187 
AA5 11 12 N ALA B 193 ? N ALA B 190 O ILE B 211 ? O ILE B 208 
AA6 1  2  N GLY A 275 ? N GLY A 272 O GLY B 275 ? O GLY B 272 
AA7 1  2  N MET B 4   ? N MET B 1   O LEU B 32  ? O LEU B 29  
AA8 1  2  O LEU B 100 ? O LEU B 97  N LEU B 43  ? N LEU B 40  
AA8 2  3  N LEU B 42  ? N LEU B 39  O ASP B 77  ? O ASP B 74  
AA8 3  4  N MET B 73  ? N MET B 70  O VAL B 90  ? O VAL B 87  
AA8 4  5  N LEU B 89  ? N LEU B 86  O LEU B 124 ? O LEU B 121 
AA9 1  2  O LEU B 100 ? O LEU B 97  N LEU B 43  ? N LEU B 40  
AA9 2  3  N VAL B 48  ? N VAL B 45  O VAL B 352 ? O VAL B 349 
AA9 3  4  O LYS B 349 ? O LYS B 346 N THR B 324 ? N THR B 321 
AB1 1  2  N TRP B 109 ? N TRP B 106 O MET B 116 ? O MET B 113 
# 
_pdbx_entry_details.entry_id                   9JLY 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 66  ? ? 179.94  144.90 
2  1 THR A 108 ? ? -76.19  25.56  
3  1 PHE A 153 ? ? -141.08 -59.59 
4  1 ALA A 213 ? ? -102.31 65.34  
5  1 GLU A 341 ? ? -92.95  32.32  
6  1 ALA B 66  ? ? -178.17 144.75 
7  1 THR B 108 ? ? -73.13  27.02  
8  1 PHE B 153 ? ? -142.52 -56.45 
9  1 LEU B 202 ? ? 86.90   -21.80 
10 1 ALA B 213 ? ? -110.06 68.42  
11 1 ALA B 227 ? ? -116.59 79.73  
12 1 GLN B 314 ? ? 58.68   12.52  
13 1 GLU B 341 ? ? -107.80 47.29  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAP PA   P N R 247 
NAP O1A  O N N 248 
NAP O2A  O N N 249 
NAP O5B  O N N 250 
NAP C5B  C N N 251 
NAP C4B  C N R 252 
NAP O4B  O N N 253 
NAP C3B  C N R 254 
NAP O3B  O N N 255 
NAP C2B  C N R 256 
NAP O2B  O N N 257 
NAP C1B  C N R 258 
NAP N9A  N Y N 259 
NAP C8A  C Y N 260 
NAP N7A  N Y N 261 
NAP C5A  C Y N 262 
NAP C6A  C Y N 263 
NAP N6A  N N N 264 
NAP N1A  N Y N 265 
NAP C2A  C Y N 266 
NAP N3A  N Y N 267 
NAP C4A  C Y N 268 
NAP O3   O N N 269 
NAP PN   P N N 270 
NAP O1N  O N N 271 
NAP O2N  O N N 272 
NAP O5D  O N N 273 
NAP C5D  C N N 274 
NAP C4D  C N R 275 
NAP O4D  O N N 276 
NAP C3D  C N S 277 
NAP O3D  O N N 278 
NAP C2D  C N R 279 
NAP O2D  O N N 280 
NAP C1D  C N R 281 
NAP N1N  N Y N 282 
NAP C2N  C Y N 283 
NAP C3N  C Y N 284 
NAP C7N  C N N 285 
NAP O7N  O N N 286 
NAP N7N  N N N 287 
NAP C4N  C Y N 288 
NAP C5N  C Y N 289 
NAP C6N  C Y N 290 
NAP P2B  P N N 291 
NAP O1X  O N N 292 
NAP O2X  O N N 293 
NAP O3X  O N N 294 
NAP HOA2 H N N 295 
NAP H51A H N N 296 
NAP H52A H N N 297 
NAP H4B  H N N 298 
NAP H3B  H N N 299 
NAP HO3A H N N 300 
NAP H2B  H N N 301 
NAP H1B  H N N 302 
NAP H8A  H N N 303 
NAP H61A H N N 304 
NAP H62A H N N 305 
NAP H2A  H N N 306 
NAP H51N H N N 307 
NAP H52N H N N 308 
NAP H4D  H N N 309 
NAP H3D  H N N 310 
NAP HO3N H N N 311 
NAP H2D  H N N 312 
NAP HO2N H N N 313 
NAP H1D  H N N 314 
NAP H2N  H N N 315 
NAP H71N H N N 316 
NAP H72N H N N 317 
NAP H4N  H N N 318 
NAP H5N  H N N 319 
NAP H6N  H N N 320 
NAP HOP2 H N N 321 
NAP HOP3 H N N 322 
PHE N    N N N 323 
PHE CA   C N S 324 
PHE C    C N N 325 
PHE O    O N N 326 
PHE CB   C N N 327 
PHE CG   C Y N 328 
PHE CD1  C Y N 329 
PHE CD2  C Y N 330 
PHE CE1  C Y N 331 
PHE CE2  C Y N 332 
PHE CZ   C Y N 333 
PHE OXT  O N N 334 
PHE H    H N N 335 
PHE H2   H N N 336 
PHE HA   H N N 337 
PHE HB2  H N N 338 
PHE HB3  H N N 339 
PHE HD1  H N N 340 
PHE HD2  H N N 341 
PHE HE1  H N N 342 
PHE HE2  H N N 343 
PHE HZ   H N N 344 
PHE HXT  H N N 345 
PRO N    N N N 346 
PRO CA   C N S 347 
PRO C    C N N 348 
PRO O    O N N 349 
PRO CB   C N N 350 
PRO CG   C N N 351 
PRO CD   C N N 352 
PRO OXT  O N N 353 
PRO H    H N N 354 
PRO HA   H N N 355 
PRO HB2  H N N 356 
PRO HB3  H N N 357 
PRO HG2  H N N 358 
PRO HG3  H N N 359 
PRO HD2  H N N 360 
PRO HD3  H N N 361 
PRO HXT  H N N 362 
SER N    N N N 363 
SER CA   C N S 364 
SER C    C N N 365 
SER O    O N N 366 
SER CB   C N N 367 
SER OG   O N N 368 
SER OXT  O N N 369 
SER H    H N N 370 
SER H2   H N N 371 
SER HA   H N N 372 
SER HB2  H N N 373 
SER HB3  H N N 374 
SER HG   H N N 375 
SER HXT  H N N 376 
THR N    N N N 377 
THR CA   C N S 378 
THR C    C N N 379 
THR O    O N N 380 
THR CB   C N R 381 
THR OG1  O N N 382 
THR CG2  C N N 383 
THR OXT  O N N 384 
THR H    H N N 385 
THR H2   H N N 386 
THR HA   H N N 387 
THR HB   H N N 388 
THR HG1  H N N 389 
THR HG21 H N N 390 
THR HG22 H N N 391 
THR HG23 H N N 392 
THR HXT  H N N 393 
TRP N    N N N 394 
TRP CA   C N S 395 
TRP C    C N N 396 
TRP O    O N N 397 
TRP CB   C N N 398 
TRP CG   C Y N 399 
TRP CD1  C Y N 400 
TRP CD2  C Y N 401 
TRP NE1  N Y N 402 
TRP CE2  C Y N 403 
TRP CE3  C Y N 404 
TRP CZ2  C Y N 405 
TRP CZ3  C Y N 406 
TRP CH2  C Y N 407 
TRP OXT  O N N 408 
TRP H    H N N 409 
TRP H2   H N N 410 
TRP HA   H N N 411 
TRP HB2  H N N 412 
TRP HB3  H N N 413 
TRP HD1  H N N 414 
TRP HE1  H N N 415 
TRP HE3  H N N 416 
TRP HZ2  H N N 417 
TRP HZ3  H N N 418 
TRP HH2  H N N 419 
TRP HXT  H N N 420 
TYR N    N N N 421 
TYR CA   C N S 422 
TYR C    C N N 423 
TYR O    O N N 424 
TYR CB   C N N 425 
TYR CG   C Y N 426 
TYR CD1  C Y N 427 
TYR CD2  C Y N 428 
TYR CE1  C Y N 429 
TYR CE2  C Y N 430 
TYR CZ   C Y N 431 
TYR OH   O N N 432 
TYR OXT  O N N 433 
TYR H    H N N 434 
TYR H2   H N N 435 
TYR HA   H N N 436 
TYR HB2  H N N 437 
TYR HB3  H N N 438 
TYR HD1  H N N 439 
TYR HD2  H N N 440 
TYR HE1  H N N 441 
TYR HE2  H N N 442 
TYR HH   H N N 443 
TYR HXT  H N N 444 
VAL N    N N N 445 
VAL CA   C N S 446 
VAL C    C N N 447 
VAL O    O N N 448 
VAL CB   C N N 449 
VAL CG1  C N N 450 
VAL CG2  C N N 451 
VAL OXT  O N N 452 
VAL H    H N N 453 
VAL H2   H N N 454 
VAL HA   H N N 455 
VAL HB   H N N 456 
VAL HG11 H N N 457 
VAL HG12 H N N 458 
VAL HG13 H N N 459 
VAL HG21 H N N 460 
VAL HG22 H N N 461 
VAL HG23 H N N 462 
VAL HXT  H N N 463 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAP PA  O1A  doub N N 235 
NAP PA  O2A  sing N N 236 
NAP PA  O5B  sing N N 237 
NAP PA  O3   sing N N 238 
NAP O2A HOA2 sing N N 239 
NAP O5B C5B  sing N N 240 
NAP C5B C4B  sing N N 241 
NAP C5B H51A sing N N 242 
NAP C5B H52A sing N N 243 
NAP C4B O4B  sing N N 244 
NAP C4B C3B  sing N N 245 
NAP C4B H4B  sing N N 246 
NAP O4B C1B  sing N N 247 
NAP C3B O3B  sing N N 248 
NAP C3B C2B  sing N N 249 
NAP C3B H3B  sing N N 250 
NAP O3B HO3A sing N N 251 
NAP C2B O2B  sing N N 252 
NAP C2B C1B  sing N N 253 
NAP C2B H2B  sing N N 254 
NAP O2B P2B  sing N N 255 
NAP C1B N9A  sing N N 256 
NAP C1B H1B  sing N N 257 
NAP N9A C8A  sing Y N 258 
NAP N9A C4A  sing Y N 259 
NAP C8A N7A  doub Y N 260 
NAP C8A H8A  sing N N 261 
NAP N7A C5A  sing Y N 262 
NAP C5A C6A  sing Y N 263 
NAP C5A C4A  doub Y N 264 
NAP C6A N6A  sing N N 265 
NAP C6A N1A  doub Y N 266 
NAP N6A H61A sing N N 267 
NAP N6A H62A sing N N 268 
NAP N1A C2A  sing Y N 269 
NAP C2A N3A  doub Y N 270 
NAP C2A H2A  sing N N 271 
NAP N3A C4A  sing Y N 272 
NAP O3  PN   sing N N 273 
NAP PN  O1N  doub N N 274 
NAP PN  O2N  sing N N 275 
NAP PN  O5D  sing N N 276 
NAP O5D C5D  sing N N 277 
NAP C5D C4D  sing N N 278 
NAP C5D H51N sing N N 279 
NAP C5D H52N sing N N 280 
NAP C4D O4D  sing N N 281 
NAP C4D C3D  sing N N 282 
NAP C4D H4D  sing N N 283 
NAP O4D C1D  sing N N 284 
NAP C3D O3D  sing N N 285 
NAP C3D C2D  sing N N 286 
NAP C3D H3D  sing N N 287 
NAP O3D HO3N sing N N 288 
NAP C2D O2D  sing N N 289 
NAP C2D C1D  sing N N 290 
NAP C2D H2D  sing N N 291 
NAP O2D HO2N sing N N 292 
NAP C1D N1N  sing N N 293 
NAP C1D H1D  sing N N 294 
NAP N1N C2N  sing Y N 295 
NAP N1N C6N  doub Y N 296 
NAP C2N C3N  doub Y N 297 
NAP C2N H2N  sing N N 298 
NAP C3N C7N  sing N N 299 
NAP C3N C4N  sing Y N 300 
NAP C7N O7N  doub N N 301 
NAP C7N N7N  sing N N 302 
NAP N7N H71N sing N N 303 
NAP N7N H72N sing N N 304 
NAP C4N C5N  doub Y N 305 
NAP C4N H4N  sing N N 306 
NAP C5N C6N  sing Y N 307 
NAP C5N H5N  sing N N 308 
NAP C6N H6N  sing N N 309 
NAP P2B O1X  doub N N 310 
NAP P2B O2X  sing N N 311 
NAP P2B O3X  sing N N 312 
NAP O2X HOP2 sing N N 313 
NAP O3X HOP3 sing N N 314 
PHE N   CA   sing N N 315 
PHE N   H    sing N N 316 
PHE N   H2   sing N N 317 
PHE CA  C    sing N N 318 
PHE CA  CB   sing N N 319 
PHE CA  HA   sing N N 320 
PHE C   O    doub N N 321 
PHE C   OXT  sing N N 322 
PHE CB  CG   sing N N 323 
PHE CB  HB2  sing N N 324 
PHE CB  HB3  sing N N 325 
PHE CG  CD1  doub Y N 326 
PHE CG  CD2  sing Y N 327 
PHE CD1 CE1  sing Y N 328 
PHE CD1 HD1  sing N N 329 
PHE CD2 CE2  doub Y N 330 
PHE CD2 HD2  sing N N 331 
PHE CE1 CZ   doub Y N 332 
PHE CE1 HE1  sing N N 333 
PHE CE2 CZ   sing Y N 334 
PHE CE2 HE2  sing N N 335 
PHE CZ  HZ   sing N N 336 
PHE OXT HXT  sing N N 337 
PRO N   CA   sing N N 338 
PRO N   CD   sing N N 339 
PRO N   H    sing N N 340 
PRO CA  C    sing N N 341 
PRO CA  CB   sing N N 342 
PRO CA  HA   sing N N 343 
PRO C   O    doub N N 344 
PRO C   OXT  sing N N 345 
PRO CB  CG   sing N N 346 
PRO CB  HB2  sing N N 347 
PRO CB  HB3  sing N N 348 
PRO CG  CD   sing N N 349 
PRO CG  HG2  sing N N 350 
PRO CG  HG3  sing N N 351 
PRO CD  HD2  sing N N 352 
PRO CD  HD3  sing N N 353 
PRO OXT HXT  sing N N 354 
SER N   CA   sing N N 355 
SER N   H    sing N N 356 
SER N   H2   sing N N 357 
SER CA  C    sing N N 358 
SER CA  CB   sing N N 359 
SER CA  HA   sing N N 360 
SER C   O    doub N N 361 
SER C   OXT  sing N N 362 
SER CB  OG   sing N N 363 
SER CB  HB2  sing N N 364 
SER CB  HB3  sing N N 365 
SER OG  HG   sing N N 366 
SER OXT HXT  sing N N 367 
THR N   CA   sing N N 368 
THR N   H    sing N N 369 
THR N   H2   sing N N 370 
THR CA  C    sing N N 371 
THR CA  CB   sing N N 372 
THR CA  HA   sing N N 373 
THR C   O    doub N N 374 
THR C   OXT  sing N N 375 
THR CB  OG1  sing N N 376 
THR CB  CG2  sing N N 377 
THR CB  HB   sing N N 378 
THR OG1 HG1  sing N N 379 
THR CG2 HG21 sing N N 380 
THR CG2 HG22 sing N N 381 
THR CG2 HG23 sing N N 382 
THR OXT HXT  sing N N 383 
TRP N   CA   sing N N 384 
TRP N   H    sing N N 385 
TRP N   H2   sing N N 386 
TRP CA  C    sing N N 387 
TRP CA  CB   sing N N 388 
TRP CA  HA   sing N N 389 
TRP C   O    doub N N 390 
TRP C   OXT  sing N N 391 
TRP CB  CG   sing N N 392 
TRP CB  HB2  sing N N 393 
TRP CB  HB3  sing N N 394 
TRP CG  CD1  doub Y N 395 
TRP CG  CD2  sing Y N 396 
TRP CD1 NE1  sing Y N 397 
TRP CD1 HD1  sing N N 398 
TRP CD2 CE2  doub Y N 399 
TRP CD2 CE3  sing Y N 400 
TRP NE1 CE2  sing Y N 401 
TRP NE1 HE1  sing N N 402 
TRP CE2 CZ2  sing Y N 403 
TRP CE3 CZ3  doub Y N 404 
TRP CE3 HE3  sing N N 405 
TRP CZ2 CH2  doub Y N 406 
TRP CZ2 HZ2  sing N N 407 
TRP CZ3 CH2  sing Y N 408 
TRP CZ3 HZ3  sing N N 409 
TRP CH2 HH2  sing N N 410 
TRP OXT HXT  sing N N 411 
TYR N   CA   sing N N 412 
TYR N   H    sing N N 413 
TYR N   H2   sing N N 414 
TYR CA  C    sing N N 415 
TYR CA  CB   sing N N 416 
TYR CA  HA   sing N N 417 
TYR C   O    doub N N 418 
TYR C   OXT  sing N N 419 
TYR CB  CG   sing N N 420 
TYR CB  HB2  sing N N 421 
TYR CB  HB3  sing N N 422 
TYR CG  CD1  doub Y N 423 
TYR CG  CD2  sing Y N 424 
TYR CD1 CE1  sing Y N 425 
TYR CD1 HD1  sing N N 426 
TYR CD2 CE2  doub Y N 427 
TYR CD2 HD2  sing N N 428 
TYR CE1 CZ   doub Y N 429 
TYR CE1 HE1  sing N N 430 
TYR CE2 CZ   sing Y N 431 
TYR CE2 HE2  sing N N 432 
TYR CZ  OH   sing N N 433 
TYR OH  HH   sing N N 434 
TYR OXT HXT  sing N N 435 
VAL N   CA   sing N N 436 
VAL N   H    sing N N 437 
VAL N   H2   sing N N 438 
VAL CA  C    sing N N 439 
VAL CA  CB   sing N N 440 
VAL CA  HA   sing N N 441 
VAL C   O    doub N N 442 
VAL C   OXT  sing N N 443 
VAL CB  CG1  sing N N 444 
VAL CB  CG2  sing N N 445 
VAL CB  HB   sing N N 446 
VAL CG1 HG11 sing N N 447 
VAL CG1 HG12 sing N N 448 
VAL CG1 HG13 sing N N 449 
VAL CG2 HG21 sing N N 450 
VAL CG2 HG22 sing N N 451 
VAL CG2 HG23 sing N N 452 
VAL OXT HXT  sing N N 453 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           82173702 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2J3H 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9JLY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011107 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011107 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004906 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LEU A 1 1   ? 105.143 81.068  254.739 1.00 73.50  ? -2  LEU A N   1 
ATOM   2    C CA  . LEU A 1 1   ? 106.103 82.093  255.143 1.00 77.25  ? -2  LEU A CA  1 
ATOM   3    C C   . LEU A 1 1   ? 106.003 83.449  254.449 1.00 80.34  ? -2  LEU A C   1 
ATOM   4    O O   . LEU A 1 1   ? 106.962 84.229  254.564 1.00 82.56  ? -2  LEU A O   1 
ATOM   5    C CB  . LEU A 1 1   ? 107.521 81.592  254.924 1.00 76.00  ? -2  LEU A CB  1 
ATOM   6    C CG  . LEU A 1 1   ? 108.063 80.710  256.030 1.00 86.99  ? -2  LEU A CG  1 
ATOM   7    C CD1 . LEU A 1 1   ? 109.526 80.342  255.738 1.00 82.55  ? -2  LEU A CD1 1 
ATOM   8    C CD2 . LEU A 1 1   ? 107.887 81.419  257.372 1.00 74.74  ? -2  LEU A CD2 1 
ATOM   9    N N   . GLY A 1 2   ? 104.902 83.765  253.754 1.00 68.91  ? -1  GLY A N   1 
ATOM   10   C CA  . GLY A 1 2   ? 104.859 85.076  253.140 1.00 72.19  ? -1  GLY A CA  1 
ATOM   11   C C   . GLY A 1 2   ? 104.607 85.107  251.645 1.00 69.85  ? -1  GLY A C   1 
ATOM   12   O O   . GLY A 1 2   ? 104.763 84.096  250.943 1.00 65.97  ? -1  GLY A O   1 
ATOM   13   N N   . SER A 1 3   ? 104.197 86.270  251.149 1.00 66.43  ? 0   SER A N   1 
ATOM   14   C CA  . SER A 1 3   ? 103.960 86.514  249.736 1.00 57.09  ? 0   SER A CA  1 
ATOM   15   C C   . SER A 1 3   ? 104.435 87.923  249.382 1.00 61.22  ? 0   SER A C   1 
ATOM   16   O O   . SER A 1 3   ? 104.967 88.654  250.222 1.00 64.22  ? 0   SER A O   1 
ATOM   17   C CB  . SER A 1 3   ? 102.484 86.324  249.402 1.00 60.19  ? 0   SER A CB  1 
ATOM   18   O OG  . SER A 1 3   ? 101.799 87.563  249.392 1.00 56.96  ? 0   SER A OG  1 
ATOM   19   N N   . MET A 1 4   ? 104.249 88.312  248.120 1.00 61.63  ? 1   MET A N   1 
ATOM   20   C CA  . MET A 1 4   ? 104.815 89.561  247.627 1.00 56.49  ? 1   MET A CA  1 
ATOM   21   C C   . MET A 1 4   ? 104.018 90.053  246.419 1.00 56.31  ? 1   MET A C   1 
ATOM   22   O O   . MET A 1 4   ? 103.549 89.244  245.619 1.00 55.85  ? 1   MET A O   1 
ATOM   23   C CB  . MET A 1 4   ? 106.283 89.330  247.273 1.00 51.65  ? 1   MET A CB  1 
ATOM   24   C CG  . MET A 1 4   ? 107.024 90.500  246.700 1.00 59.85  ? 1   MET A CG  1 
ATOM   25   S SD  . MET A 1 4   ? 108.782 90.068  246.507 1.00 65.17  ? 1   MET A SD  1 
ATOM   26   C CE  . MET A 1 4   ? 108.654 88.569  245.536 1.00 54.64  ? 1   MET A CE  1 
ATOM   27   N N   . LYS A 1 5   ? 103.860 91.375  246.305 1.00 56.25  ? 2   LYS A N   1 
ATOM   28   C CA  . LYS A 1 5   ? 103.197 92.001  245.163 1.00 51.42  ? 2   LYS A CA  1 
ATOM   29   C C   . LYS A 1 5   ? 104.203 92.185  244.041 1.00 53.91  ? 2   LYS A C   1 
ATOM   30   O O   . LYS A 1 5   ? 105.321 92.644  244.286 1.00 54.02  ? 2   LYS A O   1 
ATOM   31   C CB  . LYS A 1 5   ? 102.597 93.362  245.518 1.00 50.46  ? 2   LYS A CB  1 
ATOM   32   C CG  . LYS A 1 5   ? 101.107 93.405  245.745 1.00 51.92  ? 2   LYS A CG  1 
ATOM   33   C CD  . LYS A 1 5   ? 100.586 92.239  246.520 1.00 59.07  ? 2   LYS A CD  1 
ATOM   34   C CE  . LYS A 1 5   ? 99.091  92.434  246.747 1.00 60.02  ? 2   LYS A CE  1 
ATOM   35   N NZ  . LYS A 1 5   ? 98.418  91.217  247.295 1.00 60.45  ? 2   LYS A NZ  1 
ATOM   36   N N   . THR A 1 6   ? 103.810 91.779  242.824 1.00 55.78  ? 3   THR A N   1 
ATOM   37   C CA  . THR A 1 6   ? 104.634 91.809  241.617 1.00 48.65  ? 3   THR A CA  1 
ATOM   38   C C   . THR A 1 6   ? 103.811 92.194  240.395 1.00 51.78  ? 3   THR A C   1 
ATOM   39   O O   . THR A 1 6   ? 102.622 91.880  240.286 1.00 50.12  ? 3   THR A O   1 
ATOM   40   C CB  . THR A 1 6   ? 105.319 90.463  241.330 1.00 47.76  ? 3   THR A CB  1 
ATOM   41   O OG1 . THR A 1 6   ? 104.320 89.458  241.156 1.00 54.11  ? 3   THR A OG1 1 
ATOM   42   C CG2 . THR A 1 6   ? 106.278 90.059  242.405 1.00 53.62  ? 3   THR A CG2 1 
ATOM   43   N N   . GLU A 1 7   ? 104.454 92.923  239.493 1.00 51.61  ? 4   GLU A N   1 
ATOM   44   C CA  . GLU A 1 7   ? 103.864 93.236  238.207 1.00 52.60  ? 4   GLU A CA  1 
ATOM   45   C C   . GLU A 1 7   ? 104.273 92.200  237.166 1.00 52.24  ? 4   GLU A C   1 
ATOM   46   O O   . GLU A 1 7   ? 105.392 91.674  237.188 1.00 47.94  ? 4   GLU A O   1 
ATOM   47   C CB  . GLU A 1 7   ? 104.250 94.650  237.765 1.00 55.13  ? 4   GLU A CB  1 
ATOM   48   C CG  . GLU A 1 7   ? 103.468 95.734  238.509 1.00 54.07  ? 4   GLU A CG  1 
ATOM   49   C CD  . GLU A 1 7   ? 103.642 97.133  237.923 1.00 62.18  ? 4   GLU A CD  1 
ATOM   50   O OE1 . GLU A 1 7   ? 104.751 97.465  237.446 1.00 65.78  ? 4   GLU A OE1 1 
ATOM   51   O OE2 . GLU A 1 7   ? 102.649 97.894  237.903 1.00 59.59  ? 4   GLU A OE2 1 
ATOM   52   N N   . ARG A 1 8   ? 103.335 91.896  236.270 1.00 53.88  ? 5   ARG A N   1 
ATOM   53   C CA  . ARG A 1 8   ? 103.523 90.982  235.155 1.00 50.00  ? 5   ARG A CA  1 
ATOM   54   C C   . ARG A 1 8   ? 102.845 91.553  233.925 1.00 52.77  ? 5   ARG A C   1 
ATOM   55   O O   . ARG A 1 8   ? 101.787 92.184  234.022 1.00 58.24  ? 5   ARG A O   1 
ATOM   56   C CB  . ARG A 1 8   ? 102.923 89.606  235.422 1.00 43.52  ? 5   ARG A CB  1 
ATOM   57   C CG  . ARG A 1 8   ? 103.537 88.887  236.532 1.00 48.85  ? 5   ARG A CG  1 
ATOM   58   C CD  . ARG A 1 8   ? 102.965 87.506  236.619 1.00 51.93  ? 5   ARG A CD  1 
ATOM   59   N NE  . ARG A 1 8   ? 101.522 87.506  236.454 1.00 46.38  ? 5   ARG A NE  1 
ATOM   60   C CZ  . ARG A 1 8   ? 100.813 86.413  236.233 1.00 46.96  ? 5   ARG A CZ  1 
ATOM   61   N NH1 . ARG A 1 8   ? 101.391 85.226  236.150 1.00 48.65  ? 5   ARG A NH1 1 
ATOM   62   N NH2 . ARG A 1 8   ? 99.493  86.514  236.095 1.00 47.80  ? 5   ARG A NH2 1 
ATOM   63   N N   . TRP A 1 9   ? 103.463 91.349  232.776 1.00 47.48  ? 6   TRP A N   1 
ATOM   64   C CA  . TRP A 1 9   ? 102.791 91.569  231.512 1.00 47.99  ? 6   TRP A CA  1 
ATOM   65   C C   . TRP A 1 9   ? 102.207 90.236  231.071 1.00 49.83  ? 6   TRP A C   1 
ATOM   66   O O   . TRP A 1 9   ? 102.954 89.276  230.847 1.00 50.35  ? 6   TRP A O   1 
ATOM   67   C CB  . TRP A 1 9   ? 103.766 92.090  230.473 1.00 45.80  ? 6   TRP A CB  1 
ATOM   68   C CG  . TRP A 1 9   ? 104.150 93.478  230.664 1.00 46.41  ? 6   TRP A CG  1 
ATOM   69   C CD1 . TRP A 1 9   ? 105.338 93.948  231.142 1.00 48.08  ? 6   TRP A CD1 1 
ATOM   70   C CD2 . TRP A 1 9   ? 103.348 94.619  230.378 1.00 48.15  ? 6   TRP A CD2 1 
ATOM   71   N NE1 . TRP A 1 9   ? 105.328 95.320  231.151 1.00 50.59  ? 6   TRP A NE1 1 
ATOM   72   C CE2 . TRP A 1 9   ? 104.115 95.754  230.679 1.00 50.38  ? 6   TRP A CE2 1 
ATOM   73   C CE3 . TRP A 1 9   ? 102.066 94.794  229.867 1.00 46.11  ? 6   TRP A CE3 1 
ATOM   74   C CZ2 . TRP A 1 9   ? 103.634 97.039  230.491 1.00 45.12  ? 6   TRP A CZ2 1 
ATOM   75   C CZ3 . TRP A 1 9   ? 101.600 96.063  229.689 1.00 42.43  ? 6   TRP A CZ3 1 
ATOM   76   C CH2 . TRP A 1 9   ? 102.375 97.167  229.996 1.00 38.75  ? 6   TRP A CH2 1 
ATOM   77   N N   . VAL A 1 10  ? 100.887 90.165  230.960 1.00 46.41  ? 7   VAL A N   1 
ATOM   78   C CA  . VAL A 1 10  ? 100.227 88.932  230.567 1.00 49.01  ? 7   VAL A CA  1 
ATOM   79   C C   . VAL A 1 10  ? 99.699  89.079  229.147 1.00 51.10  ? 7   VAL A C   1 
ATOM   80   O O   . VAL A 1 10  ? 99.605  90.182  228.607 1.00 54.07  ? 7   VAL A O   1 
ATOM   81   C CB  . VAL A 1 10  ? 99.099  88.543  231.528 1.00 49.63  ? 7   VAL A CB  1 
ATOM   82   C CG1 . VAL A 1 10  ? 99.670  88.183  232.883 1.00 47.74  ? 7   VAL A CG1 1 
ATOM   83   C CG2 . VAL A 1 10  ? 98.070  89.672  231.614 1.00 51.47  ? 7   VAL A CG2 1 
ATOM   84   N N   . VAL A 1 11  ? 99.354  87.943  228.537 1.00 49.67  ? 8   VAL A N   1 
ATOM   85   C CA  . VAL A 1 11  ? 98.841  87.915  227.165 1.00 50.78  ? 8   VAL A CA  1 
ATOM   86   C C   . VAL A 1 11  ? 97.329  88.108  227.220 1.00 52.47  ? 8   VAL A C   1 
ATOM   87   O O   . VAL A 1 11  ? 96.588  87.215  227.641 1.00 54.46  ? 8   VAL A O   1 
ATOM   88   C CB  . VAL A 1 11  ? 99.217  86.620  226.431 1.00 49.34  ? 8   VAL A CB  1 
ATOM   89   C CG1 . VAL A 1 11  ? 98.338  86.417  225.235 1.00 52.22  ? 8   VAL A CG1 1 
ATOM   90   C CG2 . VAL A 1 11  ? 100.661 86.684  225.949 1.00 47.63  ? 8   VAL A CG2 1 
ATOM   91   N N   . ARG A 1 12  ? 96.879  89.290  226.794 1.00 52.82  ? 9   ARG A N   1 
ATOM   92   C CA  . ARG A 1 12  ? 95.469  89.659  226.805 1.00 55.15  ? 9   ARG A CA  1 
ATOM   93   C C   . ARG A 1 12  ? 94.736  89.143  225.575 1.00 58.75  ? 9   ARG A C   1 
ATOM   94   O O   . ARG A 1 12  ? 93.614  88.628  225.679 1.00 59.86  ? 9   ARG A O   1 
ATOM   95   C CB  . ARG A 1 12  ? 95.343  91.171  226.899 1.00 56.70  ? 9   ARG A CB  1 
ATOM   96   C CG  . ARG A 1 12  ? 93.956  91.686  226.932 1.00 56.37  ? 9   ARG A CG  1 
ATOM   97   C CD  . ARG A 1 12  ? 94.047  93.172  227.104 1.00 63.40  ? 9   ARG A CD  1 
ATOM   98   N NE  . ARG A 1 12  ? 92.773  93.821  226.846 1.00 80.78  ? 9   ARG A NE  1 
ATOM   99   C CZ  . ARG A 1 12  ? 92.584  95.128  226.939 1.00 89.33  ? 9   ARG A CZ  1 
ATOM   100  N NH1 . ARG A 1 12  ? 93.582  95.947  227.251 1.00 79.97  ? 9   ARG A NH1 1 
ATOM   101  N NH2 . ARG A 1 12  ? 91.361  95.619  226.747 1.00 87.83  ? 9   ARG A NH2 1 
ATOM   102  N N   . GLU A 1 13  ? 95.330  89.284  224.397 1.00 57.06  ? 10  GLU A N   1 
ATOM   103  C CA  . GLU A 1 13  ? 94.596  88.877  223.218 1.00 60.05  ? 10  GLU A CA  1 
ATOM   104  C C   . GLU A 1 13  ? 95.554  88.333  222.177 1.00 59.60  ? 10  GLU A C   1 
ATOM   105  O O   . GLU A 1 13  ? 96.693  88.788  222.066 1.00 59.01  ? 10  GLU A O   1 
ATOM   106  C CB  . GLU A 1 13  ? 93.790  90.050  222.659 1.00 60.01  ? 10  GLU A CB  1 
ATOM   107  C CG  . GLU A 1 13  ? 92.654  89.603  221.783 1.00 64.11  ? 10  GLU A CG  1 
ATOM   108  C CD  . GLU A 1 13  ? 92.118  90.695  220.890 1.00 70.36  ? 10  GLU A CD  1 
ATOM   109  O OE1 . GLU A 1 13  ? 92.123  91.879  221.326 1.00 66.50  ? 10  GLU A OE1 1 
ATOM   110  O OE2 . GLU A 1 13  ? 91.670  90.346  219.765 1.00 72.76  ? 10  GLU A OE2 1 
ATOM   111  N N   . HIS A 1 14  ? 95.075  87.346  221.420 1.00 61.97  ? 11  HIS A N   1 
ATOM   112  C CA  . HIS A 1 14  ? 95.826  86.771  220.313 1.00 61.59  ? 11  HIS A CA  1 
ATOM   113  C C   . HIS A 1 14  ? 95.498  87.505  219.017 1.00 62.76  ? 11  HIS A C   1 
ATOM   114  O O   . HIS A 1 14  ? 94.340  87.539  218.587 1.00 58.81  ? 11  HIS A O   1 
ATOM   115  C CB  . HIS A 1 14  ? 95.534  85.282  220.184 1.00 58.29  ? 11  HIS A CB  1 
ATOM   116  C CG  . HIS A 1 14  ? 96.134  84.455  221.277 1.00 58.20  ? 11  HIS A CG  1 
ATOM   117  N ND1 . HIS A 1 14  ? 95.712  83.175  221.565 1.00 57.50  ? 11  HIS A ND1 1 
ATOM   118  C CD2 . HIS A 1 14  ? 97.160  84.710  222.121 1.00 57.21  ? 11  HIS A CD2 1 
ATOM   119  C CE1 . HIS A 1 14  ? 96.438  82.683  222.549 1.00 54.11  ? 11  HIS A CE1 1 
ATOM   120  N NE2 . HIS A 1 14  ? 97.326  83.594  222.903 1.00 57.19  ? 11  HIS A NE2 1 
ATOM   121  N N   . VAL A 1 15  ? 96.527  88.088  218.402 1.00 63.13  ? 12  VAL A N   1 
ATOM   122  C CA  . VAL A 1 15  ? 96.425  88.824  217.149 1.00 63.83  ? 12  VAL A CA  1 
ATOM   123  C C   . VAL A 1 15  ? 97.514  88.318  216.215 1.00 64.77  ? 12  VAL A C   1 
ATOM   124  O O   . VAL A 1 15  ? 98.684  88.258  216.606 1.00 67.53  ? 12  VAL A O   1 
ATOM   125  C CB  . VAL A 1 15  ? 96.550  90.342  217.375 1.00 62.79  ? 12  VAL A CB  1 
ATOM   126  C CG1 . VAL A 1 15  ? 96.584  91.077  216.048 1.00 63.91  ? 12  VAL A CG1 1 
ATOM   127  C CG2 . VAL A 1 15  ? 95.384  90.821  218.197 1.00 59.82  ? 12  VAL A CG2 1 
ATOM   128  N N   . GLU A 1 16  ? 97.127  87.930  214.996 1.00 66.25  ? 13  GLU A N   1 
ATOM   129  C CA  . GLU A 1 16  ? 98.075  87.398  214.020 1.00 67.27  ? 13  GLU A CA  1 
ATOM   130  C C   . GLU A 1 16  ? 98.753  88.551  213.283 1.00 66.12  ? 13  GLU A C   1 
ATOM   131  O O   . GLU A 1 16  ? 98.266  89.689  213.287 1.00 61.23  ? 13  GLU A O   1 
ATOM   132  C CB  . GLU A 1 16  ? 97.374  86.485  213.014 1.00 57.05  ? 13  GLU A CB  1 
ATOM   133  C CG  . GLU A 1 16  ? 96.629  85.298  213.626 1.00 63.35  ? 13  GLU A CG  1 
ATOM   134  C CD  . GLU A 1 16  ? 97.371  83.978  213.521 1.00 72.67  ? 13  GLU A CD  1 
ATOM   135  O OE1 . GLU A 1 16  ? 98.595  84.000  213.247 1.00 74.73  ? 13  GLU A OE1 1 
ATOM   136  O OE2 . GLU A 1 16  ? 96.718  82.915  213.694 1.00 73.20  ? 13  GLU A OE2 1 
ATOM   137  N N   . GLY A 1 17  ? 99.942  88.290  212.746 1.00 55.74  ? 14  GLY A N   1 
ATOM   138  C CA  . GLY A 1 17  ? 100.555 89.343  211.981 1.00 57.67  ? 14  GLY A CA  1 
ATOM   139  C C   . GLY A 1 17  ? 101.338 90.317  212.821 1.00 57.03  ? 14  GLY A C   1 
ATOM   140  O O   . GLY A 1 17  ? 101.613 90.084  213.993 1.00 69.15  ? 14  GLY A O   1 
ATOM   141  N N   . VAL A 1 18  ? 101.688 91.444  212.211 1.00 60.27  ? 15  VAL A N   1 
ATOM   142  C CA  . VAL A 1 18  ? 102.377 92.497  212.953 1.00 62.17  ? 15  VAL A CA  1 
ATOM   143  C C   . VAL A 1 18  ? 101.565 92.841  214.195 1.00 63.24  ? 15  VAL A C   1 
ATOM   144  O O   . VAL A 1 18  ? 100.431 93.325  214.078 1.00 64.38  ? 15  VAL A O   1 
ATOM   145  C CB  . VAL A 1 18  ? 102.596 93.756  212.108 1.00 61.98  ? 15  VAL A CB  1 
ATOM   146  C CG1 . VAL A 1 18  ? 103.371 94.777  212.930 1.00 60.65  ? 15  VAL A CG1 1 
ATOM   147  C CG2 . VAL A 1 18  ? 103.290 93.421  210.791 1.00 60.62  ? 15  VAL A CG2 1 
ATOM   148  N N   . PRO A 1 19  ? 102.101 92.619  215.392 1.00 66.54  ? 16  PRO A N   1 
ATOM   149  C CA  . PRO A 1 19  ? 101.291 92.774  216.600 1.00 65.57  ? 16  PRO A CA  1 
ATOM   150  C C   . PRO A 1 19  ? 100.979 94.236  216.905 1.00 65.66  ? 16  PRO A C   1 
ATOM   151  O O   . PRO A 1 19  ? 101.627 95.165  216.413 1.00 59.39  ? 16  PRO A O   1 
ATOM   152  C CB  . PRO A 1 19  ? 102.166 92.141  217.687 1.00 62.16  ? 16  PRO A CB  1 
ATOM   153  C CG  . PRO A 1 19  ? 103.540 92.132  217.124 1.00 56.50  ? 16  PRO A CG  1 
ATOM   154  C CD  . PRO A 1 19  ? 103.394 91.967  215.674 1.00 61.93  ? 16  PRO A CD  1 
ATOM   155  N N   . ASP A 1 20  ? 99.874  94.421  217.642 1.00 66.43  ? 17  ASP A N   1 
ATOM   156  C CA  . ASP A 1 20  ? 99.526  95.685  218.300 1.00 65.46  ? 17  ASP A CA  1 
ATOM   157  C C   . ASP A 1 20  ? 99.766  95.511  219.803 1.00 61.80  ? 17  ASP A C   1 
ATOM   158  O O   . ASP A 1 20  ? 98.939  94.928  220.513 1.00 63.33  ? 17  ASP A O   1 
ATOM   159  C CB  . ASP A 1 20  ? 98.086  96.095  218.020 1.00 57.47  ? 17  ASP A CB  1 
ATOM   160  C CG  . ASP A 1 20  ? 97.760  97.459  218.603 1.00 63.61  ? 17  ASP A CG  1 
ATOM   161  O OD1 . ASP A 1 20  ? 98.694  98.170  219.064 1.00 59.16  ? 17  ASP A OD1 1 
ATOM   162  O OD2 . ASP A 1 20  ? 96.565  97.818  218.616 1.00 74.91  ? 17  ASP A OD2 1 
ATOM   163  N N   . ALA A 1 21  ? 100.884 96.042  220.300 1.00 56.03  ? 18  ALA A N   1 
ATOM   164  C CA  . ALA A 1 21  ? 101.310 95.684  221.650 1.00 59.45  ? 18  ALA A CA  1 
ATOM   165  C C   . ALA A 1 21  ? 100.315 96.153  222.715 1.00 60.40  ? 18  ALA A C   1 
ATOM   166  O O   . ALA A 1 21  ? 100.035 95.418  223.673 1.00 58.11  ? 18  ALA A O   1 
ATOM   167  C CB  . ALA A 1 21  ? 102.707 96.241  221.913 1.00 56.46  ? 18  ALA A CB  1 
ATOM   168  N N   . ALA A 1 22  ? 99.775  97.370  222.573 1.00 54.42  ? 19  ALA A N   1 
ATOM   169  C CA  . ALA A 1 22  ? 98.808  97.861  223.550 1.00 54.10  ? 19  ALA A CA  1 
ATOM   170  C C   . ALA A 1 22  ? 97.541  97.026  223.569 1.00 57.07  ? 19  ALA A C   1 
ATOM   171  O O   . ALA A 1 22  ? 96.800  97.047  224.558 1.00 54.41  ? 19  ALA A O   1 
ATOM   172  C CB  . ALA A 1 22  ? 98.454  99.316  223.276 1.00 55.34  ? 19  ALA A CB  1 
ATOM   173  N N   . ARG A 1 23  ? 97.248  96.336  222.478 1.00 53.85  ? 20  ARG A N   1 
ATOM   174  C CA  . ARG A 1 23  ? 96.044  95.531  222.424 1.00 58.87  ? 20  ARG A CA  1 
ATOM   175  C C   . ARG A 1 23  ? 96.290  94.131  222.962 1.00 63.15  ? 20  ARG A C   1 
ATOM   176  O O   . ARG A 1 23  ? 95.410  93.547  223.616 1.00 59.61  ? 20  ARG A O   1 
ATOM   177  C CB  . ARG A 1 23  ? 95.547  95.477  220.978 1.00 57.15  ? 20  ARG A CB  1 
ATOM   178  C CG  . ARG A 1 23  ? 94.426  94.503  220.712 1.00 62.01  ? 20  ARG A CG  1 
ATOM   179  C CD  . ARG A 1 23  ? 94.166  94.408  219.218 1.00 63.69  ? 20  ARG A CD  1 
ATOM   180  N NE  . ARG A 1 23  ? 93.063  93.505  218.912 1.00 60.76  ? 20  ARG A NE  1 
ATOM   181  C CZ  . ARG A 1 23  ? 92.761  93.085  217.693 1.00 62.53  ? 20  ARG A CZ  1 
ATOM   182  N NH1 . ARG A 1 23  ? 93.462  93.464  216.635 1.00 70.31  ? 20  ARG A NH1 1 
ATOM   183  N NH2 . ARG A 1 23  ? 91.734  92.260  217.529 1.00 67.41  ? 20  ARG A NH2 1 
ATOM   184  N N   . ILE A 1 24  ? 97.503  93.620  222.741 1.00 63.47  ? 21  ILE A N   1 
ATOM   185  C CA  . ILE A 1 24  ? 97.848  92.245  223.080 1.00 59.91  ? 21  ILE A CA  1 
ATOM   186  C C   . ILE A 1 24  ? 98.205  92.085  224.550 1.00 58.16  ? 21  ILE A C   1 
ATOM   187  O O   . ILE A 1 24  ? 97.926  91.033  225.138 1.00 59.38  ? 21  ILE A O   1 
ATOM   188  C CB  . ILE A 1 24  ? 99.001  91.776  222.182 1.00 56.78  ? 21  ILE A CB  1 
ATOM   189  C CG1 . ILE A 1 24  ? 98.471  91.516  220.766 1.00 62.85  ? 21  ILE A CG1 1 
ATOM   190  C CG2 . ILE A 1 24  ? 99.725  90.568  222.811 1.00 50.50  ? 21  ILE A CG2 1 
ATOM   191  C CD1 . ILE A 1 24  ? 99.503  90.988  219.759 1.00 64.92  ? 21  ILE A CD1 1 
ATOM   192  N N   . TYR A 1 25  ? 98.821  93.095  225.168 1.00 56.36  ? 22  TYR A N   1 
ATOM   193  C CA  . TYR A 1 25  ? 99.424  92.953  226.487 1.00 55.91  ? 22  TYR A CA  1 
ATOM   194  C C   . TYR A 1 25  ? 98.709  93.797  227.532 1.00 55.31  ? 22  TYR A C   1 
ATOM   195  O O   . TYR A 1 25  ? 98.050  94.792  227.219 1.00 58.66  ? 22  TYR A O   1 
ATOM   196  C CB  . TYR A 1 25  ? 100.906 93.331  226.447 1.00 56.57  ? 22  TYR A CB  1 
ATOM   197  C CG  . TYR A 1 25  ? 101.714 92.347  225.654 1.00 54.42  ? 22  TYR A CG  1 
ATOM   198  C CD1 . TYR A 1 25  ? 101.807 91.028  226.063 1.00 53.32  ? 22  TYR A CD1 1 
ATOM   199  C CD2 . TYR A 1 25  ? 102.352 92.722  224.489 1.00 50.32  ? 22  TYR A CD2 1 
ATOM   200  C CE1 . TYR A 1 25  ? 102.520 90.122  225.350 1.00 53.03  ? 22  TYR A CE1 1 
ATOM   201  C CE2 . TYR A 1 25  ? 103.070 91.825  223.776 1.00 47.66  ? 22  TYR A CE2 1 
ATOM   202  C CZ  . TYR A 1 25  ? 103.149 90.526  224.204 1.00 51.29  ? 22  TYR A CZ  1 
ATOM   203  O OH  . TYR A 1 25  ? 103.876 89.609  223.487 1.00 54.81  ? 22  TYR A OH  1 
ATOM   204  N N   . GLU A 1 26  ? 98.849  93.374  228.790 1.00 52.50  ? 23  GLU A N   1 
ATOM   205  C CA  . GLU A 1 26  ? 98.192  94.031  229.914 1.00 52.78  ? 23  GLU A CA  1 
ATOM   206  C C   . GLU A 1 26  ? 99.056  93.858  231.151 1.00 56.39  ? 23  GLU A C   1 
ATOM   207  O O   . GLU A 1 26  ? 99.425  92.730  231.505 1.00 55.65  ? 23  GLU A O   1 
ATOM   208  C CB  . GLU A 1 26  ? 96.786  93.466  230.156 1.00 53.11  ? 23  GLU A CB  1 
ATOM   209  C CG  . GLU A 1 26  ? 95.969  94.118  231.269 1.00 41.46  ? 23  GLU A CG  1 
ATOM   210  C CD  . GLU A 1 26  ? 94.502  93.710  231.207 1.00 50.70  ? 23  GLU A CD  1 
ATOM   211  O OE1 . GLU A 1 26  ? 93.759  94.204  230.338 1.00 58.56  ? 23  GLU A OE1 1 
ATOM   212  O OE2 . GLU A 1 26  ? 94.092  92.827  231.970 1.00 62.12  ? 23  GLU A OE2 1 
ATOM   213  N N   . LYS A 1 27  ? 99.400  94.981  231.782 1.00 55.11  ? 24  LYS A N   1 
ATOM   214  C CA  . LYS A 1 27  ? 100.144 94.944  233.031 1.00 49.52  ? 24  LYS A CA  1 
ATOM   215  C C   . LYS A 1 27  ? 99.155  94.664  234.147 1.00 47.71  ? 24  LYS A C   1 
ATOM   216  O O   . LYS A 1 27  ? 98.186  95.408  234.315 1.00 49.80  ? 24  LYS A O   1 
ATOM   217  C CB  . LYS A 1 27  ? 100.884 96.261  233.269 1.00 48.32  ? 24  LYS A CB  1 
ATOM   218  C CG  . LYS A 1 27  ? 101.884 96.226  234.415 1.00 50.87  ? 24  LYS A CG  1 
ATOM   219  C CD  . LYS A 1 27  ? 102.829 97.404  234.384 1.00 44.72  ? 24  LYS A CD  1 
ATOM   220  C CE  . LYS A 1 27  ? 102.116 98.668  234.751 1.00 44.79  ? 24  LYS A CE  1 
ATOM   221  N NZ  . LYS A 1 27  ? 103.081 99.654  235.287 1.00 49.18  ? 24  LYS A NZ  1 
ATOM   222  N N   . VAL A 1 28  ? 99.369  93.574  234.878 1.00 50.93  ? 25  VAL A N   1 
ATOM   223  C CA  . VAL A 1 28  ? 98.562  93.250  236.045 1.00 52.42  ? 25  VAL A CA  1 
ATOM   224  C C   . VAL A 1 28  ? 99.504  93.216  237.223 1.00 48.19  ? 25  VAL A C   1 
ATOM   225  O O   . VAL A 1 28  ? 100.719 93.088  237.064 1.00 49.93  ? 25  VAL A O   1 
ATOM   226  C CB  . VAL A 1 28  ? 97.809  91.908  235.944 1.00 52.35  ? 25  VAL A CB  1 
ATOM   227  C CG1 . VAL A 1 28  ? 97.007  91.831  234.664 1.00 48.52  ? 25  VAL A CG1 1 
ATOM   228  C CG2 . VAL A 1 28  ? 98.793  90.744  236.051 1.00 50.64  ? 25  VAL A CG2 1 
ATOM   229  N N   . GLU A 1 29  ? 98.931  93.400  238.408 1.00 49.14  ? 26  GLU A N   1 
ATOM   230  C CA  . GLU A 1 29  ? 99.607  93.133  239.670 1.00 52.51  ? 26  GLU A CA  1 
ATOM   231  C C   . GLU A 1 29  ? 99.221  91.732  240.110 1.00 55.49  ? 26  GLU A C   1 
ATOM   232  O O   . GLU A 1 29  ? 98.056  91.340  240.018 1.00 58.45  ? 26  GLU A O   1 
ATOM   233  C CB  . GLU A 1 29  ? 99.235  94.145  240.755 1.00 49.49  ? 26  GLU A CB  1 
ATOM   234  C CG  . GLU A 1 29  ? 99.707  93.740  242.138 1.00 59.81  ? 26  GLU A CG  1 
ATOM   235  C CD  . GLU A 1 29  ? 99.160  94.615  243.270 1.00 68.18  ? 26  GLU A CD  1 
ATOM   236  O OE1 . GLU A 1 29  ? 99.536  95.809  243.330 1.00 70.31  ? 26  GLU A OE1 1 
ATOM   237  O OE2 . GLU A 1 29  ? 98.373  94.102  244.109 1.00 65.16  ? 26  GLU A OE2 1 
ATOM   238  N N   . THR A 1 30  ? 100.201 90.971  240.567 1.00 54.97  ? 27  THR A N   1 
ATOM   239  C CA  . THR A 1 30  ? 99.987  89.557  240.826 1.00 59.19  ? 27  THR A CA  1 
ATOM   240  C C   . THR A 1 30  ? 100.710 89.170  242.107 1.00 58.93  ? 27  THR A C   1 
ATOM   241  O O   . THR A 1 30  ? 101.904 89.451  242.260 1.00 54.15  ? 27  THR A O   1 
ATOM   242  C CB  . THR A 1 30  ? 100.423 88.712  239.605 1.00 58.56  ? 27  THR A CB  1 
ATOM   243  O OG1 . THR A 1 30  ? 99.399  88.774  238.588 1.00 57.89  ? 27  THR A OG1 1 
ATOM   244  C CG2 . THR A 1 30  ? 100.728 87.262  239.979 1.00 52.96  ? 27  THR A CG2 1 
ATOM   245  N N   . GLU A 1 31  ? 99.967  88.546  243.030 1.00 62.73  ? 28  GLU A N   1 
ATOM   246  C CA  . GLU A 1 31  ? 100.509 88.157  244.327 1.00 58.51  ? 28  GLU A CA  1 
ATOM   247  C C   . GLU A 1 31  ? 101.347 86.909  244.162 1.00 56.87  ? 28  GLU A C   1 
ATOM   248  O O   . GLU A 1 31  ? 100.835 85.872  243.736 1.00 63.87  ? 28  GLU A O   1 
ATOM   249  C CB  . GLU A 1 31  ? 99.398  87.881  245.327 1.00 54.90  ? 28  GLU A CB  1 
ATOM   250  C CG  . GLU A 1 31  ? 99.903  87.877  246.734 1.00 62.35  ? 28  GLU A CG  1 
ATOM   251  C CD  . GLU A 1 31  ? 98.797  87.783  247.778 1.00 69.80  ? 28  GLU A CD  1 
ATOM   252  O OE1 . GLU A 1 31  ? 97.699  88.337  247.545 1.00 66.38  ? 28  GLU A OE1 1 
ATOM   253  O OE2 . GLU A 1 31  ? 99.027  87.132  248.828 1.00 67.82  ? 28  GLU A OE2 1 
ATOM   254  N N   . LEU A 1 32  ? 102.634 87.012  244.469 1.00 54.33  ? 29  LEU A N   1 
ATOM   255  C CA  . LEU A 1 32  ? 103.562 85.919  244.239 1.00 55.46  ? 29  LEU A CA  1 
ATOM   256  C C   . LEU A 1 32  ? 103.849 85.230  245.570 1.00 55.88  ? 29  LEU A C   1 
ATOM   257  O O   . LEU A 1 32  ? 104.412 85.837  246.485 1.00 56.16  ? 29  LEU A O   1 
ATOM   258  C CB  . LEU A 1 32  ? 104.855 86.410  243.584 1.00 47.84  ? 29  LEU A CB  1 
ATOM   259  C CG  . LEU A 1 32  ? 105.893 85.289  243.434 1.00 47.72  ? 29  LEU A CG  1 
ATOM   260  C CD1 . LEU A 1 32  ? 105.292 84.108  242.693 1.00 52.24  ? 29  LEU A CD1 1 
ATOM   261  C CD2 . LEU A 1 32  ? 107.157 85.747  242.758 1.00 43.83  ? 29  LEU A CD2 1 
ATOM   262  N N   . ASN A 1 33  ? 103.501 83.955  245.644 1.00 53.86  ? 30  ASN A N   1 
ATOM   263  C CA  . ASN A 1 33  ? 103.768 83.119  246.805 1.00 58.86  ? 30  ASN A CA  1 
ATOM   264  C C   . ASN A 1 33  ? 105.281 82.914  246.947 1.00 60.22  ? 30  ASN A C   1 
ATOM   265  O O   . ASN A 1 33  ? 105.939 82.468  246.002 1.00 61.96  ? 30  ASN A O   1 
ATOM   266  C CB  . ASN A 1 33  ? 103.015 81.804  246.604 1.00 59.76  ? 30  ASN A CB  1 
ATOM   267  C CG  . ASN A 1 33  ? 103.324 80.762  247.647 1.00 61.95  ? 30  ASN A CG  1 
ATOM   268  O OD1 . ASN A 1 33  ? 104.438 80.672  248.172 1.00 57.97  ? 30  ASN A OD1 1 
ATOM   269  N ND2 . ASN A 1 33  ? 102.332 79.924  247.925 1.00 66.42  ? 30  ASN A ND2 1 
ATOM   270  N N   . THR A 1 34  ? 105.842 83.270  248.109 1.00 63.16  ? 31  THR A N   1 
ATOM   271  C CA  . THR A 1 34  ? 107.295 83.272  248.323 1.00 64.70  ? 31  THR A CA  1 
ATOM   272  C C   . THR A 1 34  ? 107.844 82.108  249.165 1.00 66.41  ? 31  THR A C   1 
ATOM   273  O O   . THR A 1 34  ? 109.014 82.159  249.558 1.00 60.32  ? 31  THR A O   1 
ATOM   274  C CB  . THR A 1 34  ? 107.750 84.598  248.954 1.00 63.10  ? 31  THR A CB  1 
ATOM   275  O OG1 . THR A 1 34  ? 107.139 84.781  250.245 1.00 62.95  ? 31  THR A OG1 1 
ATOM   276  C CG2 . THR A 1 34  ? 107.415 85.769  248.028 1.00 63.19  ? 31  THR A CG2 1 
ATOM   277  N N   . ARG A 1 35  ? 107.056 81.070  249.447 1.00 70.50  ? 32  ARG A N   1 
ATOM   278  C CA  . ARG A 1 35  ? 107.545 79.921  250.217 1.00 68.76  ? 32  ARG A CA  1 
ATOM   279  C C   . ARG A 1 35  ? 108.291 78.972  249.279 1.00 76.44  ? 32  ARG A C   1 
ATOM   280  O O   . ARG A 1 35  ? 107.677 78.125  248.622 1.00 84.74  ? 32  ARG A O   1 
ATOM   281  C CB  . ARG A 1 35  ? 106.395 79.209  250.920 1.00 72.51  ? 32  ARG A CB  1 
ATOM   282  C CG  . ARG A 1 35  ? 106.859 78.076  251.847 1.00 93.04  ? 32  ARG A CG  1 
ATOM   283  C CD  . ARG A 1 35  ? 105.701 77.354  252.579 1.00 108.04 ? 32  ARG A CD  1 
ATOM   284  N NE  . ARG A 1 35  ? 104.736 76.756  251.655 1.00 108.43 ? 32  ARG A NE  1 
ATOM   285  C CZ  . ARG A 1 35  ? 104.791 75.515  251.183 1.00 107.82 ? 32  ARG A CZ  1 
ATOM   286  N NH1 . ARG A 1 35  ? 105.744 74.671  251.554 1.00 108.54 ? 32  ARG A NH1 1 
ATOM   287  N NH2 . ARG A 1 35  ? 103.866 75.111  250.314 1.00 104.25 ? 32  ARG A NH2 1 
ATOM   288  N N   . LEU A 1 36  ? 109.622 79.090  249.217 1.00 69.32  ? 33  LEU A N   1 
ATOM   289  C CA  . LEU A 1 36  ? 110.380 78.370  248.199 1.00 67.32  ? 33  LEU A CA  1 
ATOM   290  C C   . LEU A 1 36  ? 110.416 76.869  248.492 1.00 67.20  ? 33  LEU A C   1 
ATOM   291  O O   . LEU A 1 36  ? 110.558 76.443  249.637 1.00 74.03  ? 33  LEU A O   1 
ATOM   292  C CB  . LEU A 1 36  ? 111.814 78.918  248.110 1.00 62.78  ? 33  LEU A CB  1 
ATOM   293  C CG  . LEU A 1 36  ? 112.029 80.438  248.125 1.00 60.25  ? 33  LEU A CG  1 
ATOM   294  C CD1 . LEU A 1 36  ? 113.507 80.821  248.238 1.00 58.32  ? 33  LEU A CD1 1 
ATOM   295  C CD2 . LEU A 1 36  ? 111.415 81.056  246.897 1.00 59.40  ? 33  LEU A CD2 1 
ATOM   296  N N   . GLY A 1 37  ? 110.294 76.072  247.439 1.00 64.69  ? 34  GLY A N   1 
ATOM   297  C CA  . GLY A 1 37  ? 110.471 74.636  247.489 1.00 71.97  ? 34  GLY A CA  1 
ATOM   298  C C   . GLY A 1 37  ? 111.918 74.233  247.749 1.00 77.50  ? 34  GLY A C   1 
ATOM   299  O O   . GLY A 1 37  ? 112.781 75.045  248.088 1.00 76.32  ? 34  GLY A O   1 
ATOM   300  N N   . GLU A 1 38  ? 112.168 72.922  247.631 1.00 78.53  ? 35  GLU A N   1 
ATOM   301  C CA  . GLU A 1 38  ? 113.483 72.405  247.998 1.00 81.34  ? 35  GLU A CA  1 
ATOM   302  C C   . GLU A 1 38  ? 114.550 72.979  247.093 1.00 77.19  ? 35  GLU A C   1 
ATOM   303  O O   . GLU A 1 38  ? 115.653 73.307  247.543 1.00 77.20  ? 35  GLU A O   1 
ATOM   304  C CB  . GLU A 1 38  ? 113.538 70.886  247.842 1.00 87.59  ? 35  GLU A CB  1 
ATOM   305  C CG  . GLU A 1 38  ? 112.643 70.044  248.688 1.00 93.42  ? 35  GLU A CG  1 
ATOM   306  C CD  . GLU A 1 38  ? 111.271 69.893  248.044 1.00 100.47 ? 35  GLU A CD  1 
ATOM   307  O OE1 . GLU A 1 38  ? 110.880 70.785  247.250 1.00 94.86  ? 35  GLU A OE1 1 
ATOM   308  O OE2 . GLU A 1 38  ? 110.633 68.835  248.250 1.00 109.37 ? 35  GLU A OE2 1 
ATOM   309  N N   . GLU A 1 39  ? 114.213 73.174  245.823 1.00 75.70  ? 36  GLU A N   1 
ATOM   310  C CA  . GLU A 1 39  ? 115.175 73.651  244.840 1.00 79.00  ? 36  GLU A CA  1 
ATOM   311  C C   . GLU A 1 39  ? 114.728 74.927  244.164 1.00 70.60  ? 36  GLU A C   1 
ATOM   312  O O   . GLU A 1 39  ? 115.389 75.378  243.228 1.00 68.95  ? 36  GLU A O   1 
ATOM   313  C CB  . GLU A 1 39  ? 115.420 72.587  243.773 1.00 76.91  ? 36  GLU A CB  1 
ATOM   314  C CG  . GLU A 1 39  ? 115.560 71.202  244.325 1.00 86.12  ? 36  GLU A CG  1 
ATOM   315  C CD  . GLU A 1 39  ? 116.562 70.376  243.542 1.00 99.43  ? 36  GLU A CD  1 
ATOM   316  O OE1 . GLU A 1 39  ? 116.551 70.447  242.287 1.00 92.42  ? 36  GLU A OE1 1 
ATOM   317  O OE2 . GLU A 1 39  ? 117.370 69.662  244.187 1.00 108.03 ? 36  GLU A OE2 1 
ATOM   318  N N   . GLN A 1 40  ? 113.639 75.524  244.629 1.00 69.21  ? 37  GLN A N   1 
ATOM   319  C CA  . GLN A 1 40  ? 113.145 76.752  244.049 1.00 64.81  ? 37  GLN A CA  1 
ATOM   320  C C   . GLN A 1 40  ? 113.948 77.939  244.559 1.00 62.50  ? 37  GLN A C   1 
ATOM   321  O O   . GLN A 1 40  ? 114.768 77.820  245.467 1.00 65.89  ? 37  GLN A O   1 
ATOM   322  C CB  . GLN A 1 40  ? 111.665 76.898  244.371 1.00 61.91  ? 37  GLN A CB  1 
ATOM   323  C CG  . GLN A 1 40  ? 110.862 75.806  243.710 1.00 61.45  ? 37  GLN A CG  1 
ATOM   324  C CD  . GLN A 1 40  ? 109.393 76.021  243.835 1.00 62.15  ? 37  GLN A CD  1 
ATOM   325  O OE1 . GLN A 1 40  ? 108.953 76.735  244.728 1.00 66.62  ? 37  GLN A OE1 1 
ATOM   326  N NE2 . GLN A 1 40  ? 108.610 75.403  242.946 1.00 58.47  ? 37  GLN A NE2 1 
ATOM   327  N N   . MET A 1 41  ? 113.719 79.097  243.950 1.00 60.70  ? 38  MET A N   1 
ATOM   328  C CA  . MET A 1 41  ? 114.452 80.292  244.345 1.00 64.05  ? 38  MET A CA  1 
ATOM   329  C C   . MET A 1 41  ? 113.725 81.515  243.805 1.00 61.79  ? 38  MET A C   1 
ATOM   330  O O   . MET A 1 41  ? 113.282 81.529  242.653 1.00 60.88  ? 38  MET A O   1 
ATOM   331  C CB  . MET A 1 41  ? 115.912 80.223  243.881 1.00 62.58  ? 38  MET A CB  1 
ATOM   332  C CG  . MET A 1 41  ? 116.066 80.064  242.414 1.00 65.51  ? 38  MET A CG  1 
ATOM   333  S SD  . MET A 1 41  ? 117.760 79.732  241.938 1.00 66.95  ? 38  MET A SD  1 
ATOM   334  C CE  . MET A 1 41  ? 117.324 78.516  240.704 1.00 65.83  ? 38  MET A CE  1 
ATOM   335  N N   . LEU A 1 42  ? 113.678 82.555  244.626 1.00 61.18  ? 39  LEU A N   1 
ATOM   336  C CA  . LEU A 1 42  ? 112.958 83.780  244.326 1.00 58.11  ? 39  LEU A CA  1 
ATOM   337  C C   . LEU A 1 42  ? 113.859 84.716  243.526 1.00 58.49  ? 39  LEU A C   1 
ATOM   338  O O   . LEU A 1 42  ? 114.985 85.006  243.946 1.00 61.57  ? 39  LEU A O   1 
ATOM   339  C CB  . LEU A 1 42  ? 112.544 84.442  245.637 1.00 55.08  ? 39  LEU A CB  1 
ATOM   340  C CG  . LEU A 1 42  ? 111.819 85.759  245.446 1.00 53.74  ? 39  LEU A CG  1 
ATOM   341  C CD1 . LEU A 1 42  ? 110.324 85.482  245.351 1.00 50.37  ? 39  LEU A CD1 1 
ATOM   342  C CD2 . LEU A 1 42  ? 112.180 86.727  246.527 1.00 51.88  ? 39  LEU A CD2 1 
ATOM   343  N N   . LEU A 1 43  ? 113.386 85.169  242.366 1.00 50.94  ? 40  LEU A N   1 
ATOM   344  C CA  . LEU A 1 43  ? 114.243 85.892  241.435 1.00 54.48  ? 40  LEU A CA  1 
ATOM   345  C C   . LEU A 1 43  ? 113.715 87.291  241.156 1.00 53.26  ? 40  LEU A C   1 
ATOM   346  O O   . LEU A 1 43  ? 112.500 87.504  241.076 1.00 52.66  ? 40  LEU A O   1 
ATOM   347  C CB  . LEU A 1 43  ? 114.393 85.090  240.135 1.00 51.90  ? 40  LEU A CB  1 
ATOM   348  C CG  . LEU A 1 43  ? 115.200 83.813  240.372 1.00 51.77  ? 40  LEU A CG  1 
ATOM   349  C CD1 . LEU A 1 43  ? 114.537 82.623  239.756 1.00 51.63  ? 40  LEU A CD1 1 
ATOM   350  C CD2 . LEU A 1 43  ? 116.588 83.989  239.794 1.00 50.38  ? 40  LEU A CD2 1 
ATOM   351  N N   . LYS A 1 44  ? 114.642 88.234  240.994 1.00 48.22  ? 41  LYS A N   1 
ATOM   352  C CA  . LYS A 1 44  ? 114.335 89.616  240.643 1.00 53.34  ? 41  LYS A CA  1 
ATOM   353  C C   . LYS A 1 44  ? 114.785 89.888  239.216 1.00 57.03  ? 41  LYS A C   1 
ATOM   354  O O   . LYS A 1 44  ? 115.968 89.732  238.899 1.00 61.07  ? 41  LYS A O   1 
ATOM   355  C CB  . LYS A 1 44  ? 115.043 90.602  241.575 1.00 60.26  ? 41  LYS A CB  1 
ATOM   356  C CG  . LYS A 1 44  ? 114.774 92.075  241.226 1.00 60.56  ? 41  LYS A CG  1 
ATOM   357  C CD  . LYS A 1 44  ? 115.794 93.028  241.842 1.00 60.95  ? 41  LYS A CD  1 
ATOM   358  C CE  . LYS A 1 44  ? 115.236 94.466  241.955 1.00 68.09  ? 41  LYS A CE  1 
ATOM   359  N NZ  . LYS A 1 44  ? 115.120 95.251  240.669 1.00 59.10  ? 41  LYS A NZ  1 
ATOM   360  N N   . THR A 1 45  ? 113.870 90.340  238.366 1.00 58.97  ? 42  THR A N   1 
ATOM   361  C CA  . THR A 1 45  ? 114.253 90.676  237.002 1.00 59.38  ? 42  THR A CA  1 
ATOM   362  C C   . THR A 1 45  ? 114.929 92.041  236.943 1.00 50.97  ? 42  THR A C   1 
ATOM   363  O O   . THR A 1 45  ? 114.368 93.047  237.380 1.00 50.25  ? 42  THR A O   1 
ATOM   364  C CB  . THR A 1 45  ? 113.046 90.653  236.069 1.00 55.96  ? 42  THR A CB  1 
ATOM   365  O OG1 . THR A 1 45  ? 112.482 89.337  236.053 1.00 54.90  ? 42  THR A OG1 1 
ATOM   366  C CG2 . THR A 1 45  ? 113.500 90.996  234.659 1.00 56.17  ? 42  THR A CG2 1 
ATOM   367  N N   . LEU A 1 46  ? 116.123 92.070  236.374 1.00 47.40  ? 43  LEU A N   1 
ATOM   368  C CA  . LEU A 1 46  ? 116.863 93.296  236.114 1.00 57.39  ? 43  LEU A CA  1 
ATOM   369  C C   . LEU A 1 46  ? 116.718 93.768  234.667 1.00 66.72  ? 43  LEU A C   1 
ATOM   370  O O   . LEU A 1 46  ? 116.459 94.952  234.420 1.00 68.74  ? 43  LEU A O   1 
ATOM   371  C CB  . LEU A 1 46  ? 118.340 93.069  236.447 1.00 63.02  ? 43  LEU A CB  1 
ATOM   372  C CG  . LEU A 1 46  ? 118.603 92.442  237.810 1.00 55.36  ? 43  LEU A CG  1 
ATOM   373  C CD1 . LEU A 1 46  ? 120.076 92.431  238.138 1.00 52.54  ? 43  LEU A CD1 1 
ATOM   374  C CD2 . LEU A 1 46  ? 117.860 93.258  238.811 1.00 60.28  ? 43  LEU A CD2 1 
ATOM   375  N N   . TYR A 1 47  ? 116.892 92.863  233.694 1.00 66.07  ? 44  TYR A N   1 
ATOM   376  C CA  . TYR A 1 47  ? 116.651 93.151  232.284 1.00 61.70  ? 44  TYR A CA  1 
ATOM   377  C C   . TYR A 1 47  ? 115.789 92.074  231.634 1.00 61.25  ? 44  TYR A C   1 
ATOM   378  O O   . TYR A 1 47  ? 115.881 90.890  231.965 1.00 60.72  ? 44  TYR A O   1 
ATOM   379  C CB  . TYR A 1 47  ? 117.947 93.233  231.475 1.00 61.58  ? 44  TYR A CB  1 
ATOM   380  C CG  . TYR A 1 47  ? 118.972 94.265  231.911 1.00 70.52  ? 44  TYR A CG  1 
ATOM   381  C CD1 . TYR A 1 47  ? 118.915 95.577  231.434 1.00 69.26  ? 44  TYR A CD1 1 
ATOM   382  C CD2 . TYR A 1 47  ? 120.033 93.916  232.741 1.00 68.14  ? 44  TYR A CD2 1 
ATOM   383  C CE1 . TYR A 1 47  ? 119.863 96.511  231.795 1.00 67.67  ? 44  TYR A CE1 1 
ATOM   384  C CE2 . TYR A 1 47  ? 120.984 94.846  233.106 1.00 68.45  ? 44  TYR A CE2 1 
ATOM   385  C CZ  . TYR A 1 47  ? 120.893 96.141  232.633 1.00 72.26  ? 44  TYR A CZ  1 
ATOM   386  O OH  . TYR A 1 47  ? 121.833 97.074  233.008 1.00 77.01  ? 44  TYR A OH  1 
ATOM   387  N N   . VAL A 1 48  ? 114.977 92.495  230.671 1.00 57.41  ? 45  VAL A N   1 
ATOM   388  C CA  . VAL A 1 48  ? 114.231 91.595  229.810 1.00 50.73  ? 45  VAL A CA  1 
ATOM   389  C C   . VAL A 1 48  ? 114.647 91.934  228.396 1.00 58.55  ? 45  VAL A C   1 
ATOM   390  O O   . VAL A 1 48  ? 115.061 93.061  228.108 1.00 61.42  ? 45  VAL A O   1 
ATOM   391  C CB  . VAL A 1 48  ? 112.705 91.715  229.952 1.00 51.05  ? 45  VAL A CB  1 
ATOM   392  C CG1 . VAL A 1 48  ? 112.278 91.416  231.360 1.00 49.21  ? 45  VAL A CG1 1 
ATOM   393  C CG2 . VAL A 1 48  ? 112.261 93.089  229.527 1.00 49.90  ? 45  VAL A CG2 1 
ATOM   394  N N   . SER A 1 49  ? 114.572 90.945  227.523 1.00 60.17  ? 46  SER A N   1 
ATOM   395  C CA  . SER A 1 49  ? 114.869 91.131  226.116 1.00 55.99  ? 46  SER A CA  1 
ATOM   396  C C   . SER A 1 49  ? 113.561 91.238  225.349 1.00 55.15  ? 46  SER A C   1 
ATOM   397  O O   . SER A 1 49  ? 112.580 90.590  225.706 1.00 57.13  ? 46  SER A O   1 
ATOM   398  C CB  . SER A 1 49  ? 115.708 89.965  225.607 1.00 55.28  ? 46  SER A CB  1 
ATOM   399  O OG  . SER A 1 49  ? 116.057 90.147  224.252 1.00 64.68  ? 46  SER A OG  1 
ATOM   400  N N   . VAL A 1 50  ? 113.521 92.087  224.328 1.00 61.26  ? 47  VAL A N   1 
ATOM   401  C CA  . VAL A 1 50  ? 112.387 92.105  223.406 1.00 63.24  ? 47  VAL A CA  1 
ATOM   402  C C   . VAL A 1 50  ? 112.886 91.659  222.037 1.00 59.65  ? 47  VAL A C   1 
ATOM   403  O O   . VAL A 1 50  ? 113.809 92.258  221.470 1.00 60.97  ? 47  VAL A O   1 
ATOM   404  C CB  . VAL A 1 50  ? 111.689 93.476  223.343 1.00 63.45  ? 47  VAL A CB  1 
ATOM   405  C CG1 . VAL A 1 50  ? 111.150 93.871  224.747 1.00 58.58  ? 47  VAL A CG1 1 
ATOM   406  C CG2 . VAL A 1 50  ? 112.563 94.568  222.705 1.00 60.95  ? 47  VAL A CG2 1 
ATOM   407  N N   . ASP A 1 51  ? 112.271 90.599  221.514 1.00 59.69  ? 48  ASP A N   1 
ATOM   408  C CA  . ASP A 1 51  ? 112.705 89.889  220.328 1.00 62.29  ? 48  ASP A CA  1 
ATOM   409  C C   . ASP A 1 51  ? 111.539 89.580  219.408 1.00 66.49  ? 48  ASP A C   1 
ATOM   410  O O   . ASP A 1 51  ? 110.421 89.319  219.884 1.00 65.14  ? 48  ASP A O   1 
ATOM   411  C CB  . ASP A 1 51  ? 113.407 88.579  220.675 1.00 61.70  ? 48  ASP A CB  1 
ATOM   412  C CG  . ASP A 1 51  ? 114.670 88.790  221.452 1.00 67.20  ? 48  ASP A CG  1 
ATOM   413  O OD1 . ASP A 1 51  ? 114.602 89.071  222.668 1.00 64.60  ? 48  ASP A OD1 1 
ATOM   414  O OD2 . ASP A 1 51  ? 115.742 88.643  220.828 1.00 72.13  ? 48  ASP A OD2 1 
ATOM   415  N N   . PRO A 1 52  ? 111.766 89.635  218.094 1.00 65.59  ? 49  PRO A N   1 
ATOM   416  C CA  . PRO A 1 52  ? 110.681 89.332  217.152 1.00 61.07  ? 49  PRO A CA  1 
ATOM   417  C C   . PRO A 1 52  ? 110.147 87.915  217.265 1.00 60.34  ? 49  PRO A C   1 
ATOM   418  O O   . PRO A 1 52  ? 108.951 87.712  217.035 1.00 62.08  ? 49  PRO A O   1 
ATOM   419  C CB  . PRO A 1 52  ? 111.337 89.588  215.792 1.00 61.65  ? 49  PRO A CB  1 
ATOM   420  C CG  . PRO A 1 52  ? 112.414 90.568  216.085 1.00 67.04  ? 49  PRO A CG  1 
ATOM   421  C CD  . PRO A 1 52  ? 112.960 90.149  217.407 1.00 67.06  ? 49  PRO A CD  1 
ATOM   422  N N   . TYR A 1 53  ? 110.970 86.930  217.650 1.00 58.96  ? 50  TYR A N   1 
ATOM   423  C CA  . TYR A 1 53  ? 110.445 85.569  217.772 1.00 60.22  ? 50  TYR A CA  1 
ATOM   424  C C   . TYR A 1 53  ? 109.356 85.468  218.833 1.00 59.09  ? 50  TYR A C   1 
ATOM   425  O O   . TYR A 1 53  ? 108.543 84.541  218.784 1.00 57.49  ? 50  TYR A O   1 
ATOM   426  C CB  . TYR A 1 53  ? 111.575 84.551  218.055 1.00 62.40  ? 50  TYR A CB  1 
ATOM   427  C CG  . TYR A 1 53  ? 112.399 84.707  219.346 1.00 61.68  ? 50  TYR A CG  1 
ATOM   428  C CD1 . TYR A 1 53  ? 111.886 84.353  220.587 1.00 54.10  ? 50  TYR A CD1 1 
ATOM   429  C CD2 . TYR A 1 53  ? 113.717 85.157  219.295 1.00 60.57  ? 50  TYR A CD2 1 
ATOM   430  C CE1 . TYR A 1 53  ? 112.652 84.477  221.731 1.00 54.22  ? 50  TYR A CE1 1 
ATOM   431  C CE2 . TYR A 1 53  ? 114.483 85.282  220.420 1.00 54.71  ? 50  TYR A CE2 1 
ATOM   432  C CZ  . TYR A 1 53  ? 113.953 84.945  221.647 1.00 59.31  ? 50  TYR A CZ  1 
ATOM   433  O OH  . TYR A 1 53  ? 114.733 85.080  222.794 1.00 61.90  ? 50  TYR A OH  1 
ATOM   434  N N   . LEU A 1 54  ? 109.311 86.412  219.773 1.00 60.08  ? 51  LEU A N   1 
ATOM   435  C CA  . LEU A 1 54  ? 108.228 86.456  220.742 1.00 56.84  ? 51  LEU A CA  1 
ATOM   436  C C   . LEU A 1 54  ? 106.855 86.590  220.094 1.00 56.42  ? 51  LEU A C   1 
ATOM   437  O O   . LEU A 1 54  ? 105.861 86.254  220.739 1.00 56.20  ? 51  LEU A O   1 
ATOM   438  C CB  . LEU A 1 54  ? 108.435 87.603  221.728 1.00 55.75  ? 51  LEU A CB  1 
ATOM   439  C CG  . LEU A 1 54  ? 109.646 87.505  222.653 1.00 55.88  ? 51  LEU A CG  1 
ATOM   440  C CD1 . LEU A 1 54  ? 109.676 88.688  223.634 1.00 56.10  ? 51  LEU A CD1 1 
ATOM   441  C CD2 . LEU A 1 54  ? 109.660 86.176  223.386 1.00 54.88  ? 51  LEU A CD2 1 
ATOM   442  N N   . GLN A 1 55  ? 106.770 87.105  218.857 1.00 59.13  ? 52  GLN A N   1 
ATOM   443  C CA  . GLN A 1 55  ? 105.486 87.140  218.153 1.00 57.08  ? 52  GLN A CA  1 
ATOM   444  C C   . GLN A 1 55  ? 104.854 85.756  218.083 1.00 57.33  ? 52  GLN A C   1 
ATOM   445  O O   . GLN A 1 55  ? 103.623 85.630  218.146 1.00 55.97  ? 52  GLN A O   1 
ATOM   446  C CB  . GLN A 1 55  ? 105.656 87.709  216.733 1.00 56.54  ? 52  GLN A CB  1 
ATOM   447  C CG  . GLN A 1 55  ? 104.330 87.976  215.988 1.00 56.23  ? 52  GLN A CG  1 
ATOM   448  C CD  . GLN A 1 55  ? 103.795 86.745  215.239 1.00 61.85  ? 52  GLN A CD  1 
ATOM   449  O OE1 . GLN A 1 55  ? 104.416 85.680  215.232 1.00 59.93  ? 52  GLN A OE1 1 
ATOM   450  N NE2 . GLN A 1 55  ? 102.611 86.880  214.653 1.00 64.06  ? 52  GLN A NE2 1 
ATOM   451  N N   . GLY A 1 56  ? 105.674 84.713  217.966 1.00 55.91  ? 53  GLY A N   1 
ATOM   452  C CA  . GLY A 1 56  ? 105.179 83.354  217.934 1.00 54.51  ? 53  GLY A CA  1 
ATOM   453  C C   . GLY A 1 56  ? 104.825 82.794  219.296 1.00 55.82  ? 53  GLY A C   1 
ATOM   454  O O   . GLY A 1 56  ? 103.766 82.175  219.459 1.00 56.95  ? 53  GLY A O   1 
ATOM   455  N N   . ILE A 1 57  ? 105.685 83.028  220.291 1.00 57.87  ? 54  ILE A N   1 
ATOM   456  C CA  . ILE A 1 57  ? 105.422 82.529  221.640 1.00 56.26  ? 54  ILE A CA  1 
ATOM   457  C C   . ILE A 1 57  ? 104.136 83.133  222.182 1.00 57.17  ? 54  ILE A C   1 
ATOM   458  O O   . ILE A 1 57  ? 103.366 82.476  222.889 1.00 55.23  ? 54  ILE A O   1 
ATOM   459  C CB  . ILE A 1 57  ? 106.624 82.837  222.548 1.00 54.69  ? 54  ILE A CB  1 
ATOM   460  C CG1 . ILE A 1 57  ? 107.851 82.071  222.063 1.00 53.43  ? 54  ILE A CG1 1 
ATOM   461  C CG2 . ILE A 1 57  ? 106.313 82.510  223.985 1.00 63.12  ? 54  ILE A CG2 1 
ATOM   462  C CD1 . ILE A 1 57  ? 109.138 82.509  222.713 1.00 61.23  ? 54  ILE A CD1 1 
ATOM   463  N N   . CYS A 1 58  ? 103.874 84.390  221.834 1.00 58.26  ? 55  CYS A N   1 
ATOM   464  C CA  . CYS A 1 58  ? 102.662 85.052  222.287 1.00 53.93  ? 55  CYS A CA  1 
ATOM   465  C C   . CYS A 1 58  ? 101.418 84.335  221.778 1.00 58.26  ? 55  CYS A C   1 
ATOM   466  O O   . CYS A 1 58  ? 100.436 84.179  222.520 1.00 56.09  ? 55  CYS A O   1 
ATOM   467  C CB  . CYS A 1 58  ? 102.682 86.506  221.831 1.00 47.81  ? 55  CYS A CB  1 
ATOM   468  S SG  . CYS A 1 58  ? 101.320 87.466  222.419 1.00 49.33  ? 55  CYS A SG  1 
ATOM   469  N N   . LEU A 1 59  ? 101.458 83.848  220.528 1.00 58.94  ? 56  LEU A N   1 
ATOM   470  C CA  . LEU A 1 59  ? 100.310 83.145  219.964 1.00 55.41  ? 56  LEU A CA  1 
ATOM   471  C C   . LEU A 1 59  ? 100.147 81.761  220.566 1.00 58.03  ? 56  LEU A C   1 
ATOM   472  O O   . LEU A 1 59  ? 99.040  81.217  220.557 1.00 62.22  ? 56  LEU A O   1 
ATOM   473  C CB  . LEU A 1 59  ? 100.427 83.056  218.441 1.00 51.24  ? 56  LEU A CB  1 
ATOM   474  C CG  . LEU A 1 59  ? 100.353 84.396  217.704 1.00 56.69  ? 56  LEU A CG  1 
ATOM   475  C CD1 . LEU A 1 59  ? 100.493 84.240  216.197 1.00 53.48  ? 56  LEU A CD1 1 
ATOM   476  C CD2 . LEU A 1 59  ? 99.057  85.115  218.061 1.00 60.76  ? 56  LEU A CD2 1 
ATOM   477  N N   . ASP A 1 60  ? 101.201 81.201  221.137 1.00 57.34  ? 57  ASP A N   1 
ATOM   478  C CA  . ASP A 1 60  ? 101.111 79.917  221.810 1.00 59.50  ? 57  ASP A CA  1 
ATOM   479  C C   . ASP A 1 60  ? 100.997 80.068  223.319 1.00 61.81  ? 57  ASP A C   1 
ATOM   480  O O   . ASP A 1 60  ? 100.885 79.065  224.029 1.00 64.63  ? 57  ASP A O   1 
ATOM   481  C CB  . ASP A 1 60  ? 102.327 79.050  221.467 1.00 64.12  ? 57  ASP A CB  1 
ATOM   482  C CG  . ASP A 1 60  ? 102.198 78.346  220.126 1.00 71.50  ? 57  ASP A CG  1 
ATOM   483  O OD1 . ASP A 1 60  ? 101.083 78.322  219.560 1.00 72.81  ? 57  ASP A OD1 1 
ATOM   484  O OD2 . ASP A 1 60  ? 103.211 77.797  219.643 1.00 74.15  ? 57  ASP A OD2 1 
ATOM   485  N N   . THR A 1 61  ? 101.028 81.292  223.818 1.00 60.28  ? 58  THR A N   1 
ATOM   486  C CA  . THR A 1 61  ? 100.894 81.539  225.244 1.00 58.51  ? 58  THR A CA  1 
ATOM   487  C C   . THR A 1 61  ? 99.421  81.573  225.629 1.00 57.80  ? 58  THR A C   1 
ATOM   488  O O   . THR A 1 61  ? 98.658  82.341  225.034 1.00 56.45  ? 58  THR A O   1 
ATOM   489  C CB  . THR A 1 61  ? 101.574 82.848  225.629 1.00 58.30  ? 58  THR A CB  1 
ATOM   490  O OG1 . THR A 1 61  ? 103.004 82.676  225.622 1.00 56.19  ? 58  THR A OG1 1 
ATOM   491  C CG2 . THR A 1 61  ? 101.092 83.314  226.994 1.00 56.87  ? 58  THR A CG2 1 
ATOM   492  N N   . PRO A 1 62  ? 98.972  80.734  226.564 1.00 56.90  ? 59  PRO A N   1 
ATOM   493  C CA  . PRO A 1 62  ? 97.567  80.770  226.980 1.00 55.52  ? 59  PRO A CA  1 
ATOM   494  C C   . PRO A 1 62  ? 97.133  82.180  227.355 1.00 57.68  ? 59  PRO A C   1 
ATOM   495  O O   . PRO A 1 62  ? 97.878  82.918  228.001 1.00 58.23  ? 59  PRO A O   1 
ATOM   496  C CB  . PRO A 1 62  ? 97.545  79.848  228.205 1.00 53.58  ? 59  PRO A CB  1 
ATOM   497  C CG  . PRO A 1 62  ? 98.676  78.907  227.990 1.00 57.10  ? 59  PRO A CG  1 
ATOM   498  C CD  . PRO A 1 62  ? 99.741  79.719  227.307 1.00 59.60  ? 59  PRO A CD  1 
ATOM   499  N N   . ILE A 1 63  ? 95.907  82.548  226.961 1.00 57.97  ? 60  ILE A N   1 
ATOM   500  C CA  . ILE A 1 63  ? 95.385  83.868  227.309 1.00 52.82  ? 60  ILE A CA  1 
ATOM   501  C C   . ILE A 1 63  ? 95.390  83.993  228.829 1.00 50.72  ? 60  ILE A C   1 
ATOM   502  O O   . ILE A 1 63  ? 94.925  83.098  229.545 1.00 47.32  ? 60  ILE A O   1 
ATOM   503  C CB  . ILE A 1 63  ? 93.971  84.062  226.742 1.00 45.30  ? 60  ILE A CB  1 
ATOM   504  C CG1 . ILE A 1 63  ? 93.995  84.083  225.219 1.00 50.57  ? 60  ILE A CG1 1 
ATOM   505  C CG2 . ILE A 1 63  ? 93.319  85.343  227.297 1.00 44.81  ? 60  ILE A CG2 1 
ATOM   506  C CD1 . ILE A 1 63  ? 94.210  85.449  224.603 1.00 57.39  ? 60  ILE A CD1 1 
ATOM   507  N N   . GLY A 1 64  ? 95.951  85.088  229.331 1.00 52.10  ? 61  GLY A N   1 
ATOM   508  C CA  . GLY A 1 64  ? 96.054  85.326  230.753 1.00 52.96  ? 61  GLY A CA  1 
ATOM   509  C C   . GLY A 1 64  ? 97.405  85.010  231.369 1.00 51.51  ? 61  GLY A C   1 
ATOM   510  O O   . GLY A 1 64  ? 97.703  85.524  232.445 1.00 48.84  ? 61  GLY A O   1 
ATOM   511  N N   . ASP A 1 65  ? 98.231  84.191  230.720 1.00 56.01  ? 62  ASP A N   1 
ATOM   512  C CA  . ASP A 1 65  ? 99.539  83.848  231.262 1.00 54.17  ? 62  ASP A CA  1 
ATOM   513  C C   . ASP A 1 65  ? 100.568 84.935  230.938 1.00 55.80  ? 62  ASP A C   1 
ATOM   514  O O   . ASP A 1 65  ? 100.393 85.764  230.036 1.00 52.47  ? 62  ASP A O   1 
ATOM   515  C CB  . ASP A 1 65  ? 100.038 82.511  230.698 1.00 57.93  ? 62  ASP A CB  1 
ATOM   516  C CG  . ASP A 1 65  ? 99.191  81.315  231.119 1.00 65.65  ? 62  ASP A CG  1 
ATOM   517  O OD1 . ASP A 1 65  ? 98.112  81.496  231.730 1.00 67.59  ? 62  ASP A OD1 1 
ATOM   518  O OD2 . ASP A 1 65  ? 99.613  80.175  230.806 1.00 66.93  ? 62  ASP A OD2 1 
ATOM   519  N N   . HIS A 1 66  ? 101.692 84.875  231.640 1.00 52.90  ? 63  HIS A N   1 
ATOM   520  C CA  . HIS A 1 66  ? 102.724 85.869  231.432 1.00 48.64  ? 63  HIS A CA  1 
ATOM   521  C C   . HIS A 1 66  ? 103.469 85.604  230.120 1.00 50.07  ? 63  HIS A C   1 
ATOM   522  O O   . HIS A 1 66  ? 103.521 84.477  229.605 1.00 44.72  ? 63  HIS A O   1 
ATOM   523  C CB  . HIS A 1 66  ? 103.695 85.868  232.611 1.00 47.96  ? 63  HIS A CB  1 
ATOM   524  C CG  . HIS A 1 66  ? 104.783 84.847  232.497 1.00 48.74  ? 63  HIS A CG  1 
ATOM   525  N ND1 . HIS A 1 66  ? 105.973 85.095  231.846 1.00 52.06  ? 63  HIS A ND1 1 
ATOM   526  C CD2 . HIS A 1 66  ? 104.857 83.573  232.938 1.00 48.80  ? 63  HIS A CD2 1 
ATOM   527  C CE1 . HIS A 1 66  ? 106.735 84.020  231.890 1.00 48.61  ? 63  HIS A CE1 1 
ATOM   528  N NE2 . HIS A 1 66  ? 106.081 83.082  232.547 1.00 52.10  ? 63  HIS A NE2 1 
ATOM   529  N N   . MET A 1 67  ? 104.032 86.682  229.573 1.00 49.96  ? 64  MET A N   1 
ATOM   530  C CA  . MET A 1 67  ? 104.800 86.647  228.328 1.00 50.42  ? 64  MET A CA  1 
ATOM   531  C C   . MET A 1 67  ? 106.233 86.196  228.588 1.00 45.02  ? 64  MET A C   1 
ATOM   532  O O   . MET A 1 67  ? 106.965 86.855  229.327 1.00 46.76  ? 64  MET A O   1 
ATOM   533  C CB  . MET A 1 67  ? 104.782 88.034  227.679 1.00 52.16  ? 64  MET A CB  1 
ATOM   534  C CG  . MET A 1 67  ? 105.501 88.143  226.341 1.00 51.71  ? 64  MET A CG  1 
ATOM   535  S SD  . MET A 1 67  ? 104.763 87.056  225.131 1.00 55.07  ? 64  MET A SD  1 
ATOM   536  C CE  . MET A 1 67  ? 106.117 85.966  224.723 1.00 51.46  ? 64  MET A CE  1 
ATOM   537  N N   . GLY A 1 68  ? 106.641 85.093  227.970 1.00 46.10  ? 65  GLY A N   1 
ATOM   538  C CA  . GLY A 1 68  ? 108.018 84.648  228.098 1.00 47.52  ? 65  GLY A CA  1 
ATOM   539  C C   . GLY A 1 68  ? 108.994 85.620  227.466 1.00 45.75  ? 65  GLY A C   1 
ATOM   540  O O   . GLY A 1 68  ? 108.622 86.486  226.685 1.00 47.08  ? 65  GLY A O   1 
ATOM   541  N N   . ALA A 1 69  ? 110.260 85.506  227.868 1.00 46.78  ? 66  ALA A N   1 
ATOM   542  C CA  . ALA A 1 69  ? 111.321 86.361  227.343 1.00 50.64  ? 66  ALA A CA  1 
ATOM   543  C C   . ALA A 1 69  ? 112.661 86.016  227.974 1.00 54.67  ? 66  ALA A C   1 
ATOM   544  O O   . ALA A 1 69  ? 112.717 85.689  229.164 1.00 52.11  ? 66  ALA A O   1 
ATOM   545  C CB  . ALA A 1 69  ? 111.028 87.842  227.594 1.00 47.99  ? 66  ALA A CB  1 
ATOM   546  N N   . ASP A 1 70  ? 113.746 86.118  227.204 1.00 57.14  ? 67  ASP A N   1 
ATOM   547  C CA  . ASP A 1 70  ? 115.069 86.058  227.808 1.00 53.93  ? 67  ASP A CA  1 
ATOM   548  C C   . ASP A 1 70  ? 115.212 87.193  228.796 1.00 54.15  ? 67  ASP A C   1 
ATOM   549  O O   . ASP A 1 70  ? 114.861 88.337  228.501 1.00 56.90  ? 67  ASP A O   1 
ATOM   550  C CB  . ASP A 1 70  ? 116.156 86.186  226.754 1.00 58.65  ? 67  ASP A CB  1 
ATOM   551  C CG  . ASP A 1 70  ? 116.858 84.893  226.510 1.00 66.46  ? 67  ASP A CG  1 
ATOM   552  O OD1 . ASP A 1 70  ? 116.541 83.959  227.257 1.00 66.78  ? 67  ASP A OD1 1 
ATOM   553  O OD2 . ASP A 1 70  ? 117.699 84.796  225.585 1.00 78.10  ? 67  ASP A OD2 1 
ATOM   554  N N   . SER A 1 71  ? 115.740 86.888  229.972 1.00 54.93  ? 68  SER A N   1 
ATOM   555  C CA  . SER A 1 71  ? 115.876 87.921  230.981 1.00 53.89  ? 68  SER A CA  1 
ATOM   556  C C   . SER A 1 71  ? 117.141 87.709  231.796 1.00 52.67  ? 68  SER A C   1 
ATOM   557  O O   . SER A 1 71  ? 117.732 86.629  231.810 1.00 53.40  ? 68  SER A O   1 
ATOM   558  C CB  . SER A 1 71  ? 114.643 87.967  231.891 1.00 53.19  ? 68  SER A CB  1 
ATOM   559  O OG  . SER A 1 71  ? 114.467 86.736  232.548 1.00 52.98  ? 68  SER A OG  1 
ATOM   560  N N   . ILE A 1 72  ? 117.531 88.772  232.491 1.00 54.78  ? 69  ILE A N   1 
ATOM   561  C CA  . ILE A 1 72  ? 118.588 88.749  233.494 1.00 53.23  ? 69  ILE A CA  1 
ATOM   562  C C   . ILE A 1 72  ? 117.940 88.937  234.865 1.00 58.49  ? 69  ILE A C   1 
ATOM   563  O O   . ILE A 1 72  ? 117.201 89.906  235.093 1.00 60.62  ? 69  ILE A O   1 
ATOM   564  C CB  . ILE A 1 72  ? 119.658 89.818  233.216 1.00 54.45  ? 69  ILE A CB  1 
ATOM   565  C CG1 . ILE A 1 72  ? 120.414 89.493  231.918 1.00 58.68  ? 69  ILE A CG1 1 
ATOM   566  C CG2 . ILE A 1 72  ? 120.580 89.979  234.396 1.00 57.11  ? 69  ILE A CG2 1 
ATOM   567  C CD1 . ILE A 1 72  ? 121.456 90.529  231.499 1.00 57.45  ? 69  ILE A CD1 1 
ATOM   568  N N   . MET A 1 73  ? 118.191 87.989  235.766 1.00 57.46  ? 70  MET A N   1 
ATOM   569  C CA  . MET A 1 73  ? 117.554 87.943  237.069 1.00 52.10  ? 70  MET A CA  1 
ATOM   570  C C   . MET A 1 73  ? 118.609 87.887  238.172 1.00 50.73  ? 70  MET A C   1 
ATOM   571  O O   . MET A 1 73  ? 119.741 87.448  237.965 1.00 51.18  ? 70  MET A O   1 
ATOM   572  C CB  . MET A 1 73  ? 116.613 86.736  237.155 1.00 51.47  ? 70  MET A CB  1 
ATOM   573  C CG  . MET A 1 73  ? 115.471 86.775  236.167 1.00 48.61  ? 70  MET A CG  1 
ATOM   574  S SD  . MET A 1 73  ? 114.817 85.146  235.705 1.00 53.74  ? 70  MET A SD  1 
ATOM   575  C CE  . MET A 1 73  ? 116.216 84.404  234.912 1.00 48.70  ? 70  MET A CE  1 
ATOM   576  N N   . GLN A 1 74  ? 118.224 88.348  239.355 1.00 54.24  ? 71  GLN A N   1 
ATOM   577  C CA  . GLN A 1 74  ? 119.058 88.264  240.547 1.00 59.54  ? 71  GLN A CA  1 
ATOM   578  C C   . GLN A 1 74  ? 118.369 87.364  241.577 1.00 58.49  ? 71  GLN A C   1 
ATOM   579  O O   . GLN A 1 74  ? 117.134 87.376  241.702 1.00 51.78  ? 71  GLN A O   1 
ATOM   580  C CB  . GLN A 1 74  ? 119.323 89.660  241.123 1.00 58.06  ? 71  GLN A CB  1 
ATOM   581  C CG  . GLN A 1 74  ? 120.366 89.684  242.221 1.00 65.61  ? 71  GLN A CG  1 
ATOM   582  C CD  . GLN A 1 74  ? 120.926 91.078  242.482 1.00 78.54  ? 71  GLN A CD  1 
ATOM   583  O OE1 . GLN A 1 74  ? 120.289 92.093  242.165 1.00 79.18  ? 71  GLN A OE1 1 
ATOM   584  N NE2 . GLN A 1 74  ? 122.117 91.133  243.083 1.00 77.60  ? 71  GLN A NE2 1 
ATOM   585  N N   . VAL A 1 75  ? 119.158 86.543  242.274 1.00 57.27  ? 72  VAL A N   1 
ATOM   586  C CA  . VAL A 1 75  ? 118.611 85.586  243.239 1.00 59.71  ? 72  VAL A CA  1 
ATOM   587  C C   . VAL A 1 75  ? 118.394 86.329  244.557 1.00 66.18  ? 72  VAL A C   1 
ATOM   588  O O   . VAL A 1 75  ? 119.345 86.640  245.282 1.00 68.26  ? 72  VAL A O   1 
ATOM   589  C CB  . VAL A 1 75  ? 119.504 84.359  243.424 1.00 58.20  ? 72  VAL A CB  1 
ATOM   590  C CG1 . VAL A 1 75  ? 118.864 83.420  244.422 1.00 61.44  ? 72  VAL A CG1 1 
ATOM   591  C CG2 . VAL A 1 75  ? 119.684 83.645  242.127 1.00 61.16  ? 72  VAL A CG2 1 
ATOM   592  N N   . LEU A 1 76  ? 117.135 86.633  244.863 1.00 62.82  ? 73  LEU A N   1 
ATOM   593  C CA  . LEU A 1 76  ? 116.830 87.283  246.127 1.00 58.16  ? 73  LEU A CA  1 
ATOM   594  C C   . LEU A 1 76  ? 117.010 86.320  247.287 1.00 67.85  ? 73  LEU A C   1 
ATOM   595  O O   . LEU A 1 76  ? 117.535 86.693  248.346 1.00 68.85  ? 73  LEU A O   1 
ATOM   596  C CB  . LEU A 1 76  ? 115.409 87.817  246.084 1.00 50.51  ? 73  LEU A CB  1 
ATOM   597  C CG  . LEU A 1 76  ? 115.365 89.032  245.165 1.00 55.51  ? 73  LEU A CG  1 
ATOM   598  C CD1 . LEU A 1 76  ? 113.929 89.424  244.867 1.00 55.19  ? 73  LEU A CD1 1 
ATOM   599  C CD2 . LEU A 1 76  ? 116.163 90.190  245.738 1.00 57.84  ? 73  LEU A CD2 1 
ATOM   600  N N   . ASP A 1 77  ? 116.639 85.063  247.074 1.00 66.85  ? 74  ASP A N   1 
ATOM   601  C CA  . ASP A 1 77  ? 116.474 84.078  248.124 1.00 64.61  ? 74  ASP A CA  1 
ATOM   602  C C   . ASP A 1 77  ? 116.385 82.720  247.474 1.00 65.30  ? 74  ASP A C   1 
ATOM   603  O O   . ASP A 1 77  ? 115.734 82.580  246.445 1.00 66.99  ? 74  ASP A O   1 
ATOM   604  C CB  . ASP A 1 77  ? 115.186 84.350  248.894 1.00 70.65  ? 74  ASP A CB  1 
ATOM   605  C CG  . ASP A 1 77  ? 115.057 83.507  250.121 1.00 77.26  ? 74  ASP A CG  1 
ATOM   606  O OD1 . ASP A 1 77  ? 116.011 82.758  250.434 1.00 80.98  ? 74  ASP A OD1 1 
ATOM   607  O OD2 . ASP A 1 77  ? 113.966 83.558  250.734 1.00 74.30  ? 74  ASP A OD2 1 
ATOM   608  N N   . ALA A 1 78  ? 116.969 81.714  248.107 1.00 71.80  ? 75  ALA A N   1 
ATOM   609  C CA  . ALA A 1 78  ? 117.055 80.413  247.465 1.00 69.68  ? 75  ALA A CA  1 
ATOM   610  C C   . ALA A 1 78  ? 116.793 79.296  248.458 1.00 72.18  ? 75  ALA A C   1 
ATOM   611  O O   . ALA A 1 78  ? 117.322 79.296  249.572 1.00 74.66  ? 75  ALA A O   1 
ATOM   612  C CB  . ALA A 1 78  ? 118.425 80.212  246.822 1.00 71.37  ? 75  ALA A CB  1 
ATOM   613  N N   . GLY A 1 79  ? 116.019 78.314  248.007 1.00 75.52  ? 76  GLY A N   1 
ATOM   614  C CA  . GLY A 1 79  ? 115.743 77.111  248.753 1.00 77.36  ? 76  GLY A CA  1 
ATOM   615  C C   . GLY A 1 79  ? 116.979 76.284  249.041 1.00 79.11  ? 76  GLY A C   1 
ATOM   616  O O   . GLY A 1 79  ? 118.092 76.589  248.597 1.00 78.84  ? 76  GLY A O   1 
ATOM   617  N N   . PRO A 1 80  ? 116.798 75.211  249.811 1.00 86.08  ? 77  PRO A N   1 
ATOM   618  C CA  . PRO A 1 80  ? 117.962 74.465  250.314 1.00 86.89  ? 77  PRO A CA  1 
ATOM   619  C C   . PRO A 1 80  ? 118.757 73.720  249.248 1.00 90.13  ? 77  PRO A C   1 
ATOM   620  O O   . PRO A 1 80  ? 119.939 73.437  249.479 1.00 95.47  ? 77  PRO A O   1 
ATOM   621  C CB  . PRO A 1 80  ? 117.339 73.490  251.327 1.00 84.45  ? 77  PRO A CB  1 
ATOM   622  C CG  . PRO A 1 80  ? 115.897 73.361  250.908 1.00 84.84  ? 77  PRO A CG  1 
ATOM   623  C CD  . PRO A 1 80  ? 115.524 74.708  250.361 1.00 86.71  ? 77  PRO A CD  1 
ATOM   624  N N   . ASN A 1 81  ? 118.172 73.385  248.100 1.00 85.22  ? 78  ASN A N   1 
ATOM   625  C CA  . ASN A 1 81  ? 118.909 72.667  247.066 1.00 80.51  ? 78  ASN A CA  1 
ATOM   626  C C   . ASN A 1 81  ? 119.040 73.457  245.774 1.00 80.45  ? 78  ASN A C   1 
ATOM   627  O O   . ASN A 1 81  ? 119.420 72.884  244.754 1.00 88.28  ? 78  ASN A O   1 
ATOM   628  C CB  . ASN A 1 81  ? 118.216 71.330  246.792 1.00 87.67  ? 78  ASN A CB  1 
ATOM   629  C CG  . ASN A 1 81  ? 118.194 70.423  248.018 1.00 94.20  ? 78  ASN A CG  1 
ATOM   630  O OD1 . ASN A 1 81  ? 119.106 70.459  248.853 1.00 84.76  ? 78  ASN A OD1 1 
ATOM   631  N ND2 . ASN A 1 81  ? 117.118 69.643  248.159 1.00 92.19  ? 78  ASN A ND2 1 
ATOM   632  N N   . ALA A 1 82  ? 118.743 74.751  245.790 1.00 82.53  ? 79  ALA A N   1 
ATOM   633  C CA  . ALA A 1 82  ? 118.728 75.556  244.573 1.00 77.66  ? 79  ALA A CA  1 
ATOM   634  C C   . ALA A 1 82  ? 120.077 75.523  243.849 1.00 76.75  ? 79  ALA A C   1 
ATOM   635  O O   . ALA A 1 82  ? 121.110 75.242  244.461 1.00 77.84  ? 79  ALA A O   1 
ATOM   636  C CB  . ALA A 1 82  ? 118.357 76.999  244.911 1.00 74.32  ? 79  ALA A CB  1 
ATOM   637  N N   . PRO A 1 83  ? 120.083 75.737  242.525 1.00 78.07  ? 80  PRO A N   1 
ATOM   638  C CA  . PRO A 1 83  ? 121.358 75.842  241.784 1.00 74.47  ? 80  PRO A CA  1 
ATOM   639  C C   . PRO A 1 83  ? 122.148 77.125  242.027 1.00 74.20  ? 80  PRO A C   1 
ATOM   640  O O   . PRO A 1 83  ? 123.297 77.202  241.572 1.00 75.35  ? 80  PRO A O   1 
ATOM   641  C CB  . PRO A 1 83  ? 120.932 75.743  240.310 1.00 65.72  ? 80  PRO A CB  1 
ATOM   642  C CG  . PRO A 1 83  ? 119.495 76.002  240.295 1.00 67.83  ? 80  PRO A CG  1 
ATOM   643  C CD  . PRO A 1 83  ? 118.944 75.544  241.617 1.00 75.52  ? 80  PRO A CD  1 
ATOM   644  N N   . PHE A 1 84  ? 121.567 78.151  242.649 1.00 73.64  ? 81  PHE A N   1 
ATOM   645  C CA  . PHE A 1 84  ? 122.262 79.418  242.851 1.00 72.51  ? 81  PHE A CA  1 
ATOM   646  C C   . PHE A 1 84  ? 121.908 79.975  244.222 1.00 75.09  ? 81  PHE A C   1 
ATOM   647  O O   . PHE A 1 84  ? 120.785 79.783  244.700 1.00 77.86  ? 81  PHE A O   1 
ATOM   648  C CB  . PHE A 1 84  ? 121.893 80.419  241.743 1.00 71.31  ? 81  PHE A CB  1 
ATOM   649  C CG  . PHE A 1 84  ? 122.000 79.834  240.363 1.00 72.74  ? 81  PHE A CG  1 
ATOM   650  C CD1 . PHE A 1 84  ? 123.239 79.662  239.760 1.00 68.54  ? 81  PHE A CD1 1 
ATOM   651  C CD2 . PHE A 1 84  ? 120.871 79.396  239.697 1.00 69.89  ? 81  PHE A CD2 1 
ATOM   652  C CE1 . PHE A 1 84  ? 123.340 79.101  238.507 1.00 63.75  ? 81  PHE A CE1 1 
ATOM   653  C CE2 . PHE A 1 84  ? 120.977 78.832  238.434 1.00 69.87  ? 81  PHE A CE2 1 
ATOM   654  C CZ  . PHE A 1 84  ? 122.212 78.690  237.839 1.00 60.40  ? 81  PHE A CZ  1 
ATOM   655  N N   . ARG A 1 85  ? 122.868 80.611  244.874 1.00 72.31  ? 82  ARG A N   1 
ATOM   656  C CA  . ARG A 1 85  ? 122.612 81.185  246.180 1.00 72.63  ? 82  ARG A CA  1 
ATOM   657  C C   . ARG A 1 85  ? 122.249 82.646  246.027 1.00 70.54  ? 82  ARG A C   1 
ATOM   658  O O   . ARG A 1 85  ? 122.502 83.253  244.984 1.00 66.27  ? 82  ARG A O   1 
ATOM   659  C CB  . ARG A 1 85  ? 123.827 81.002  247.093 1.00 77.89  ? 82  ARG A CB  1 
ATOM   660  C CG  . ARG A 1 85  ? 125.179 81.297  246.477 1.00 75.27  ? 82  ARG A CG  1 
ATOM   661  C CD  . ARG A 1 85  ? 126.281 80.842  247.449 1.00 78.59  ? 82  ARG A CD  1 
ATOM   662  N NE  . ARG A 1 85  ? 127.468 80.383  246.735 1.00 79.27  ? 82  ARG A NE  1 
ATOM   663  C CZ  . ARG A 1 85  ? 127.701 79.124  246.380 1.00 76.20  ? 82  ARG A CZ  1 
ATOM   664  N NH1 . ARG A 1 85  ? 126.868 78.145  246.705 1.00 70.90  ? 82  ARG A NH1 1 
ATOM   665  N NH2 . ARG A 1 85  ? 128.788 78.843  245.666 1.00 73.27  ? 82  ARG A NH2 1 
ATOM   666  N N   . PRO A 1 86  ? 121.666 83.263  247.063 1.00 69.94  ? 83  PRO A N   1 
ATOM   667  C CA  . PRO A 1 86  ? 121.265 84.672  246.946 1.00 66.06  ? 83  PRO A CA  1 
ATOM   668  C C   . PRO A 1 86  ? 122.434 85.575  246.601 1.00 66.57  ? 83  PRO A C   1 
ATOM   669  O O   . PRO A 1 86  ? 123.544 85.415  247.109 1.00 72.21  ? 83  PRO A O   1 
ATOM   670  C CB  . PRO A 1 86  ? 120.682 84.986  248.321 1.00 62.71  ? 83  PRO A CB  1 
ATOM   671  C CG  . PRO A 1 86  ? 120.137 83.682  248.773 1.00 70.52  ? 83  PRO A CG  1 
ATOM   672  C CD  . PRO A 1 86  ? 121.110 82.646  248.276 1.00 68.96  ? 83  PRO A CD  1 
ATOM   673  N N   . GLY A 1 87  ? 122.161 86.534  245.720 1.00 64.61  ? 84  GLY A N   1 
ATOM   674  C CA  . GLY A 1 87  ? 123.161 87.402  245.149 1.00 67.35  ? 84  GLY A CA  1 
ATOM   675  C C   . GLY A 1 87  ? 123.622 87.026  243.746 1.00 68.85  ? 84  GLY A C   1 
ATOM   676  O O   . GLY A 1 87  ? 124.107 87.907  243.020 1.00 67.23  ? 84  GLY A O   1 
ATOM   677  N N   . ASP A 1 88  ? 123.482 85.758  243.340 1.00 68.58  ? 85  ASP A N   1 
ATOM   678  C CA  . ASP A 1 88  ? 123.956 85.321  242.026 1.00 64.58  ? 85  ASP A CA  1 
ATOM   679  C C   . ASP A 1 88  ? 123.149 85.956  240.902 1.00 65.16  ? 85  ASP A C   1 
ATOM   680  O O   . ASP A 1 88  ? 121.918 86.014  240.966 1.00 63.90  ? 85  ASP A O   1 
ATOM   681  C CB  . ASP A 1 88  ? 123.845 83.804  241.896 1.00 66.64  ? 85  ASP A CB  1 
ATOM   682  C CG  . ASP A 1 88  ? 124.943 83.066  242.615 1.00 73.12  ? 85  ASP A CG  1 
ATOM   683  O OD1 . ASP A 1 88  ? 125.730 83.709  243.337 1.00 81.32  ? 85  ASP A OD1 1 
ATOM   684  O OD2 . ASP A 1 88  ? 124.999 81.827  242.481 1.00 75.24  ? 85  ASP A OD2 1 
ATOM   685  N N   . LEU A 1 89  ? 123.834 86.413  239.855 1.00 61.78  ? 86  LEU A N   1 
ATOM   686  C CA  . LEU A 1 89  ? 123.139 86.857  238.656 1.00 56.83  ? 86  LEU A CA  1 
ATOM   687  C C   . LEU A 1 89  ? 123.020 85.686  237.693 1.00 62.43  ? 86  LEU A C   1 
ATOM   688  O O   . LEU A 1 89  ? 124.003 84.987  237.427 1.00 64.34  ? 86  LEU A O   1 
ATOM   689  C CB  . LEU A 1 89  ? 123.841 88.027  237.984 1.00 56.36  ? 86  LEU A CB  1 
ATOM   690  C CG  . LEU A 1 89  ? 123.929 89.312  238.787 1.00 56.40  ? 86  LEU A CG  1 
ATOM   691  C CD1 . LEU A 1 89  ? 124.840 90.283  238.058 1.00 51.54  ? 86  LEU A CD1 1 
ATOM   692  C CD2 . LEU A 1 89  ? 122.555 89.899  239.013 1.00 56.98  ? 86  LEU A CD2 1 
ATOM   693  N N   . VAL A 1 90  ? 121.814 85.486  237.166 1.00 64.27  ? 87  VAL A N   1 
ATOM   694  C CA  . VAL A 1 90  ? 121.492 84.359  236.302 1.00 59.46  ? 87  VAL A CA  1 
ATOM   695  C C   . VAL A 1 90  ? 120.767 84.840  235.046 1.00 56.34  ? 87  VAL A C   1 
ATOM   696  O O   . VAL A 1 90  ? 120.164 85.915  235.015 1.00 53.75  ? 87  VAL A O   1 
ATOM   697  C CB  . VAL A 1 90  ? 120.644 83.317  237.064 1.00 56.67  ? 87  VAL A CB  1 
ATOM   698  C CG1 . VAL A 1 90  ? 121.396 82.818  238.278 1.00 58.73  ? 87  VAL A CG1 1 
ATOM   699  C CG2 . VAL A 1 90  ? 119.340 83.950  237.524 1.00 51.07  ? 87  VAL A CG2 1 
ATOM   700  N N   . GLN A 1 91  ? 120.828 84.009  233.999 1.00 62.51  ? 88  GLN A N   1 
ATOM   701  C CA  . GLN A 1 91  ? 120.174 84.254  232.713 1.00 59.21  ? 88  GLN A CA  1 
ATOM   702  C C   . GLN A 1 91  ? 119.274 83.070  232.368 1.00 57.59  ? 88  GLN A C   1 
ATOM   703  O O   . GLN A 1 91  ? 119.685 81.912  232.506 1.00 57.22  ? 88  GLN A O   1 
ATOM   704  C CB  . GLN A 1 91  ? 121.207 84.466  231.597 1.00 59.39  ? 88  GLN A CB  1 
ATOM   705  C CG  . GLN A 1 91  ? 120.655 85.122  230.332 1.00 63.06  ? 88  GLN A CG  1 
ATOM   706  C CD  . GLN A 1 91  ? 120.137 84.136  229.312 1.00 65.55  ? 88  GLN A CD  1 
ATOM   707  O OE1 . GLN A 1 91  ? 120.766 83.106  229.059 1.00 63.63  ? 88  GLN A OE1 1 
ATOM   708  N NE2 . GLN A 1 91  ? 119.016 84.479  228.668 1.00 60.34  ? 88  GLN A NE2 1 
ATOM   709  N N   . GLY A 1 92  ? 118.056 83.360  231.926 1.00 55.25  ? 89  GLY A N   1 
ATOM   710  C CA  . GLY A 1 92  ? 117.091 82.315  231.650 1.00 50.23  ? 89  GLY A CA  1 
ATOM   711  C C   . GLY A 1 92  ? 115.840 82.920  231.067 1.00 50.26  ? 89  GLY A C   1 
ATOM   712  O O   . GLY A 1 92  ? 115.789 84.122  230.792 1.00 52.37  ? 89  GLY A O   1 
ATOM   713  N N   . PHE A 1 93  ? 114.824 82.082  230.863 1.00 47.45  ? 90  PHE A N   1 
ATOM   714  C CA  . PHE A 1 93  ? 113.621 82.565  230.191 1.00 49.16  ? 90  PHE A CA  1 
ATOM   715  C C   . PHE A 1 93  ? 112.601 83.094  231.202 1.00 47.53  ? 90  PHE A C   1 
ATOM   716  O O   . PHE A 1 93  ? 111.453 82.670  231.246 1.00 49.83  ? 90  PHE A O   1 
ATOM   717  C CB  . PHE A 1 93  ? 113.018 81.471  229.321 1.00 47.93  ? 90  PHE A CB  1 
ATOM   718  C CG  . PHE A 1 93  ? 112.433 81.991  228.034 1.00 56.58  ? 90  PHE A CG  1 
ATOM   719  C CD1 . PHE A 1 93  ? 113.245 82.603  227.091 1.00 55.28  ? 90  PHE A CD1 1 
ATOM   720  C CD2 . PHE A 1 93  ? 111.071 81.910  227.777 1.00 58.02  ? 90  PHE A CD2 1 
ATOM   721  C CE1 . PHE A 1 93  ? 112.713 83.082  225.898 1.00 59.12  ? 90  PHE A CE1 1 
ATOM   722  C CE2 . PHE A 1 93  ? 110.537 82.406  226.586 1.00 57.16  ? 90  PHE A CE2 1 
ATOM   723  C CZ  . PHE A 1 93  ? 111.358 82.982  225.646 1.00 54.10  ? 90  PHE A CZ  1 
ATOM   724  N N   . GLY A 1 94  ? 113.011 84.122  231.944 1.00 47.55  ? 91  GLY A N   1 
ATOM   725  C CA  . GLY A 1 94  ? 112.222 84.561  233.089 1.00 51.31  ? 91  GLY A CA  1 
ATOM   726  C C   . GLY A 1 94  ? 110.890 85.189  232.721 1.00 52.41  ? 91  GLY A C   1 
ATOM   727  O O   . GLY A 1 94  ? 109.894 85.026  233.439 1.00 47.09  ? 91  GLY A O   1 
ATOM   728  N N   . GLY A 1 95  ? 110.853 85.932  231.623 1.00 53.56  ? 92  GLY A N   1 
ATOM   729  C CA  . GLY A 1 95  ? 109.609 86.521  231.169 1.00 49.42  ? 92  GLY A CA  1 
ATOM   730  C C   . GLY A 1 95  ? 109.494 87.976  231.573 1.00 50.66  ? 92  GLY A C   1 
ATOM   731  O O   . GLY A 1 95  ? 110.333 88.548  232.282 1.00 51.16  ? 92  GLY A O   1 
ATOM   732  N N   . TRP A 1 96  ? 108.411 88.574  231.087 1.00 48.73  ? 93  TRP A N   1 
ATOM   733  C CA  . TRP A 1 96  ? 108.060 89.954  231.404 1.00 47.78  ? 93  TRP A CA  1 
ATOM   734  C C   . TRP A 1 96  ? 107.367 89.996  232.761 1.00 49.10  ? 93  TRP A C   1 
ATOM   735  O O   . TRP A 1 96  ? 106.152 90.174  232.876 1.00 49.12  ? 93  TRP A O   1 
ATOM   736  C CB  . TRP A 1 96  ? 107.178 90.536  230.317 1.00 48.46  ? 93  TRP A CB  1 
ATOM   737  C CG  . TRP A 1 96  ? 107.877 90.689  229.047 1.00 49.04  ? 93  TRP A CG  1 
ATOM   738  C CD1 . TRP A 1 96  ? 109.205 90.515  228.817 1.00 48.03  ? 93  TRP A CD1 1 
ATOM   739  C CD2 . TRP A 1 96  ? 107.290 91.051  227.796 1.00 52.46  ? 93  TRP A CD2 1 
ATOM   740  N NE1 . TRP A 1 96  ? 109.483 90.751  227.499 1.00 51.21  ? 93  TRP A NE1 1 
ATOM   741  C CE2 . TRP A 1 96  ? 108.322 91.090  226.852 1.00 49.19  ? 93  TRP A CE2 1 
ATOM   742  C CE3 . TRP A 1 96  ? 105.988 91.366  227.388 1.00 51.90  ? 93  TRP A CE3 1 
ATOM   743  C CZ2 . TRP A 1 96  ? 108.094 91.415  225.532 1.00 47.95  ? 93  TRP A CZ2 1 
ATOM   744  C CZ3 . TRP A 1 96  ? 105.773 91.700  226.079 1.00 47.44  ? 93  TRP A CZ3 1 
ATOM   745  C CH2 . TRP A 1 96  ? 106.811 91.714  225.170 1.00 47.84  ? 93  TRP A CH2 1 
ATOM   746  N N   . ARG A 1 97  ? 108.168 89.786  233.799 1.00 46.87  ? 94  ARG A N   1 
ATOM   747  C CA  . ARG A 1 97  ? 107.678 89.798  235.165 1.00 49.36  ? 94  ARG A CA  1 
ATOM   748  C C   . ARG A 1 97  ? 108.709 90.485  236.034 1.00 54.24  ? 94  ARG A C   1 
ATOM   749  O O   . ARG A 1 97  ? 109.909 90.439  235.750 1.00 52.79  ? 94  ARG A O   1 
ATOM   750  C CB  . ARG A 1 97  ? 107.397 88.388  235.687 1.00 45.01  ? 94  ARG A CB  1 
ATOM   751  C CG  . ARG A 1 97  ? 106.396 87.672  234.862 1.00 45.20  ? 94  ARG A CG  1 
ATOM   752  C CD  . ARG A 1 97  ? 106.099 86.328  235.395 1.00 50.54  ? 94  ARG A CD  1 
ATOM   753  N NE  . ARG A 1 97  ? 107.215 85.408  235.231 1.00 53.62  ? 94  ARG A NE  1 
ATOM   754  C CZ  . ARG A 1 97  ? 107.159 84.130  235.576 1.00 53.85  ? 94  ARG A CZ  1 
ATOM   755  N NH1 . ARG A 1 97  ? 106.063 83.602  236.108 1.00 53.32  ? 94  ARG A NH1 1 
ATOM   756  N NH2 . ARG A 1 97  ? 108.231 83.366  235.401 1.00 51.58  ? 94  ARG A NH2 1 
ATOM   757  N N   . THR A 1 98  ? 108.233 91.132  237.098 1.00 54.84  ? 95  THR A N   1 
ATOM   758  C CA  . THR A 1 98  ? 109.182 91.788  237.980 1.00 51.03  ? 95  THR A CA  1 
ATOM   759  C C   . THR A 1 98  ? 109.874 90.762  238.856 1.00 54.85  ? 95  THR A C   1 
ATOM   760  O O   . THR A 1 98  ? 111.101 90.788  238.990 1.00 60.55  ? 95  THR A O   1 
ATOM   761  C CB  . THR A 1 98  ? 108.477 92.845  238.830 1.00 48.84  ? 95  THR A CB  1 
ATOM   762  O OG1 . THR A 1 98  ? 107.647 92.212  239.807 1.00 54.28  ? 95  THR A OG1 1 
ATOM   763  C CG2 . THR A 1 98  ? 107.618 93.719  237.969 1.00 47.73  ? 95  THR A CG2 1 
ATOM   764  N N   . HIS A 1 99  ? 109.111 89.809  239.392 1.00 55.33  ? 96  HIS A N   1 
ATOM   765  C CA  . HIS A 1 99  ? 109.655 88.744  240.214 1.00 52.74  ? 96  HIS A CA  1 
ATOM   766  C C   . HIS A 1 99  ? 108.956 87.434  239.914 1.00 57.40  ? 96  HIS A C   1 
ATOM   767  O O   . HIS A 1 99  ? 107.780 87.403  239.527 1.00 60.81  ? 96  HIS A O   1 
ATOM   768  C CB  . HIS A 1 99  ? 109.517 89.041  241.689 1.00 51.79  ? 96  HIS A CB  1 
ATOM   769  C CG  . HIS A 1 99  ? 110.143 90.330  242.081 1.00 54.40  ? 96  HIS A CG  1 
ATOM   770  N ND1 . HIS A 1 99  ? 109.562 91.545  241.803 1.00 53.02  ? 96  HIS A ND1 1 
ATOM   771  C CD2 . HIS A 1 99  ? 111.334 90.599  242.664 1.00 57.81  ? 96  HIS A CD2 1 
ATOM   772  C CE1 . HIS A 1 99  ? 110.355 92.509  242.230 1.00 63.00  ? 96  HIS A CE1 1 
ATOM   773  N NE2 . HIS A 1 99  ? 111.437 91.962  242.757 1.00 63.61  ? 96  HIS A NE2 1 
ATOM   774  N N   . LEU A 1 100 ? 109.679 86.351  240.170 1.00 51.89  ? 97  LEU A N   1 
ATOM   775  C CA  . LEU A 1 100 ? 109.205 85.027  239.824 1.00 50.61  ? 97  LEU A CA  1 
ATOM   776  C C   . LEU A 1 100 ? 109.898 84.034  240.735 1.00 49.28  ? 97  LEU A C   1 
ATOM   777  O O   . LEU A 1 100 ? 110.953 84.325  241.304 1.00 53.25  ? 97  LEU A O   1 
ATOM   778  C CB  . LEU A 1 100 ? 109.476 84.726  238.346 1.00 49.30  ? 97  LEU A CB  1 
ATOM   779  C CG  . LEU A 1 100 ? 110.955 84.803  237.965 1.00 49.32  ? 97  LEU A CG  1 
ATOM   780  C CD1 . LEU A 1 100 ? 111.271 83.758  236.961 1.00 48.81  ? 97  LEU A CD1 1 
ATOM   781  C CD2 . LEU A 1 100 ? 111.295 86.156  237.397 1.00 49.57  ? 97  LEU A CD2 1 
ATOM   782  N N   . VAL A 1 101 ? 109.301 82.852  240.850 1.00 46.09  ? 98  VAL A N   1 
ATOM   783  C CA  . VAL A 1 101 ? 109.892 81.734  241.567 1.00 49.02  ? 98  VAL A CA  1 
ATOM   784  C C   . VAL A 1 101 ? 110.130 80.627  240.560 1.00 45.65  ? 98  VAL A C   1 
ATOM   785  O O   . VAL A 1 101 ? 109.215 80.265  239.820 1.00 50.84  ? 98  VAL A O   1 
ATOM   786  C CB  . VAL A 1 101 ? 108.984 81.252  242.718 1.00 53.48  ? 98  VAL A CB  1 
ATOM   787  C CG1 . VAL A 1 101 ? 109.557 80.005  243.371 1.00 54.33  ? 98  VAL A CG1 1 
ATOM   788  C CG2 . VAL A 1 101 ? 108.837 82.341  243.773 1.00 52.36  ? 98  VAL A CG2 1 
ATOM   789  N N   . SER A 1 102 ? 111.334 80.058  240.561 1.00 47.29  ? 99  SER A N   1 
ATOM   790  C CA  . SER A 1 102 ? 111.684 79.024  239.595 1.00 52.07  ? 99  SER A CA  1 
ATOM   791  C C   . SER A 1 102 ? 112.723 78.077  240.192 1.00 57.66  ? 99  SER A C   1 
ATOM   792  O O   . SER A 1 102 ? 113.591 78.496  240.967 1.00 56.60  ? 99  SER A O   1 
ATOM   793  C CB  . SER A 1 102 ? 112.212 79.672  238.302 1.00 47.68  ? 99  SER A CB  1 
ATOM   794  O OG  . SER A 1 102 ? 112.600 78.717  237.333 1.00 52.12  ? 99  SER A OG  1 
ATOM   795  N N   . ASP A 1 103 ? 112.652 76.795  239.804 1.00 59.10  ? 100 ASP A N   1 
ATOM   796  C CA  . ASP A 1 103 ? 113.684 75.835  240.193 1.00 60.13  ? 100 ASP A CA  1 
ATOM   797  C C   . ASP A 1 103 ? 114.865 75.843  239.241 1.00 60.86  ? 100 ASP A C   1 
ATOM   798  O O   . ASP A 1 103 ? 115.810 75.070  239.442 1.00 60.91  ? 100 ASP A O   1 
ATOM   799  C CB  . ASP A 1 103 ? 113.127 74.409  240.305 1.00 59.58  ? 100 ASP A CB  1 
ATOM   800  C CG  . ASP A 1 103 ? 112.481 73.919  239.025 1.00 64.96  ? 100 ASP A CG  1 
ATOM   801  O OD1 . ASP A 1 103 ? 112.028 74.761  238.219 1.00 68.56  ? 100 ASP A OD1 1 
ATOM   802  O OD2 . ASP A 1 103 ? 112.385 72.679  238.849 1.00 63.19  ? 100 ASP A OD2 1 
ATOM   803  N N   . GLY A 1 104 ? 114.815 76.681  238.206 1.00 56.14  ? 101 GLY A N   1 
ATOM   804  C CA  . GLY A 1 104 ? 115.906 76.854  237.280 1.00 55.08  ? 101 GLY A CA  1 
ATOM   805  C C   . GLY A 1 104 ? 116.197 75.681  236.391 1.00 54.28  ? 101 GLY A C   1 
ATOM   806  O O   . GLY A 1 104 ? 117.202 75.708  235.678 1.00 57.74  ? 101 GLY A O   1 
ATOM   807  N N   . LYS A 1 105 ? 115.357 74.671  236.396 1.00 55.86  ? 102 LYS A N   1 
ATOM   808  C CA  . LYS A 1 105 ? 115.560 73.483  235.585 1.00 63.28  ? 102 LYS A CA  1 
ATOM   809  C C   . LYS A 1 105 ? 114.987 73.699  234.187 1.00 66.40  ? 102 LYS A C   1 
ATOM   810  O O   . LYS A 1 105 ? 114.184 74.610  233.962 1.00 66.99  ? 102 LYS A O   1 
ATOM   811  C CB  . LYS A 1 105 ? 114.878 72.280  236.239 1.00 60.24  ? 102 LYS A CB  1 
ATOM   812  C CG  . LYS A 1 105 ? 115.608 71.677  237.442 1.00 64.54  ? 102 LYS A CG  1 
ATOM   813  C CD  . LYS A 1 105 ? 114.728 70.613  238.102 1.00 66.01  ? 102 LYS A CD  1 
ATOM   814  C CE  . LYS A 1 105 ? 115.334 70.023  239.358 1.00 76.79  ? 102 LYS A CE  1 
ATOM   815  N NZ  . LYS A 1 105 ? 114.357 69.082  239.988 1.00 81.19  ? 102 LYS A NZ  1 
ATOM   816  N N   . PRO A 1 106 ? 115.384 72.901  233.215 1.00 60.36  ? 103 PRO A N   1 
ATOM   817  C CA  . PRO A 1 106 ? 114.746 73.017  231.908 1.00 61.99  ? 103 PRO A CA  1 
ATOM   818  C C   . PRO A 1 106 ? 113.260 72.725  232.026 1.00 66.04  ? 103 PRO A C   1 
ATOM   819  O O   . PRO A 1 106 ? 112.863 71.638  232.460 1.00 67.45  ? 103 PRO A O   1 
ATOM   820  C CB  . PRO A 1 106 ? 115.489 71.975  231.066 1.00 60.85  ? 103 PRO A CB  1 
ATOM   821  C CG  . PRO A 1 106 ? 116.797 71.843  231.721 1.00 53.12  ? 103 PRO A CG  1 
ATOM   822  C CD  . PRO A 1 106 ? 116.508 71.953  233.178 1.00 56.90  ? 103 PRO A CD  1 
ATOM   823  N N   . LYS A 1 107 ? 112.442 73.742  231.789 1.00 69.74  ? 104 LYS A N   1 
ATOM   824  C CA  . LYS A 1 107 ? 111.003 73.567  231.666 1.00 71.09  ? 104 LYS A CA  1 
ATOM   825  C C   . LYS A 1 107 ? 110.667 73.232  230.222 1.00 70.49  ? 104 LYS A C   1 
ATOM   826  O O   . LYS A 1 107 ? 111.446 73.493  229.304 1.00 68.68  ? 104 LYS A O   1 
ATOM   827  C CB  . LYS A 1 107 ? 110.251 74.818  232.115 1.00 61.85  ? 104 LYS A CB  1 
ATOM   828  C CG  . LYS A 1 107 ? 110.336 75.009  233.606 1.00 80.15  ? 104 LYS A CG  1 
ATOM   829  C CD  . LYS A 1 107 ? 109.454 76.141  234.088 1.00 105.19 ? 104 LYS A CD  1 
ATOM   830  C CE  . LYS A 1 107 ? 109.864 77.466  233.448 1.00 115.76 ? 104 LYS A CE  1 
ATOM   831  N NZ  . LYS A 1 107 ? 109.202 78.628  234.122 1.00 113.23 ? 104 LYS A NZ  1 
ATOM   832  N N   . LEU A 1 108 ? 109.519 72.613  230.025 1.00 68.15  ? 105 LEU A N   1 
ATOM   833  C CA  . LEU A 1 108 ? 109.079 72.275  228.684 1.00 67.06  ? 105 LEU A CA  1 
ATOM   834  C C   . LEU A 1 108 ? 108.034 73.285  228.238 1.00 74.30  ? 105 LEU A C   1 
ATOM   835  O O   . LEU A 1 108 ? 107.253 73.789  229.052 1.00 77.33  ? 105 LEU A O   1 
ATOM   836  C CB  . LEU A 1 108 ? 108.497 70.861  228.612 1.00 68.61  ? 105 LEU A CB  1 
ATOM   837  C CG  . LEU A 1 108 ? 107.794 70.458  227.310 1.00 67.22  ? 105 LEU A CG  1 
ATOM   838  C CD1 . LEU A 1 108 ? 108.753 70.467  226.151 1.00 70.97  ? 105 LEU A CD1 1 
ATOM   839  C CD2 . LEU A 1 108 ? 107.130 69.112  227.422 1.00 74.49  ? 105 LEU A CD2 1 
ATOM   840  N N   . TRP A 1 109 ? 108.062 73.616  226.944 1.00 76.07  ? 106 TRP A N   1 
ATOM   841  C CA  . TRP A 1 109 ? 107.102 74.551  226.360 1.00 73.83  ? 106 TRP A CA  1 
ATOM   842  C C   . TRP A 1 109 ? 105.964 73.724  225.770 1.00 79.18  ? 106 TRP A C   1 
ATOM   843  O O   . TRP A 1 109 ? 105.897 73.429  224.571 1.00 81.29  ? 106 TRP A O   1 
ATOM   844  C CB  . TRP A 1 109 ? 107.781 75.455  225.342 1.00 69.68  ? 106 TRP A CB  1 
ATOM   845  C CG  . TRP A 1 109 ? 106.889 76.528  224.795 1.00 71.17  ? 106 TRP A CG  1 
ATOM   846  C CD1 . TRP A 1 109 ? 106.675 76.813  223.482 1.00 75.10  ? 106 TRP A CD1 1 
ATOM   847  C CD2 . TRP A 1 109 ? 106.059 77.430  225.537 1.00 65.73  ? 106 TRP A CD2 1 
ATOM   848  N NE1 . TRP A 1 109 ? 105.790 77.852  223.359 1.00 74.38  ? 106 TRP A NE1 1 
ATOM   849  C CE2 . TRP A 1 109 ? 105.392 78.243  224.609 1.00 70.06  ? 106 TRP A CE2 1 
ATOM   850  C CE3 . TRP A 1 109 ? 105.820 77.630  226.892 1.00 65.17  ? 106 TRP A CE3 1 
ATOM   851  C CZ2 . TRP A 1 109 ? 104.507 79.242  224.994 1.00 65.15  ? 106 TRP A CZ2 1 
ATOM   852  C CZ3 . TRP A 1 109 ? 104.941 78.610  227.267 1.00 64.78  ? 106 TRP A CZ3 1 
ATOM   853  C CH2 . TRP A 1 109 ? 104.299 79.411  226.324 1.00 64.75  ? 106 TRP A CH2 1 
ATOM   854  N N   . GLN A 1 110 ? 105.062 73.330  226.670 1.00 80.66  ? 107 GLN A N   1 
ATOM   855  C CA  . GLN A 1 110 ? 104.002 72.384  226.340 1.00 87.87  ? 107 GLN A CA  1 
ATOM   856  C C   . GLN A 1 110 ? 103.085 72.907  225.238 1.00 88.26  ? 107 GLN A C   1 
ATOM   857  O O   . GLN A 1 110 ? 102.800 72.200  224.262 1.00 88.00  ? 107 GLN A O   1 
ATOM   858  C CB  . GLN A 1 110 ? 103.206 72.064  227.608 1.00 91.19  ? 107 GLN A CB  1 
ATOM   859  C CG  . GLN A 1 110 ? 103.978 72.264  228.937 1.00 89.53  ? 107 GLN A CG  1 
ATOM   860  C CD  . GLN A 1 110 ? 103.112 72.028  230.172 1.00 94.11  ? 107 GLN A CD  1 
ATOM   861  O OE1 . GLN A 1 110 ? 102.978 70.897  230.648 1.00 99.37  ? 107 GLN A OE1 1 
ATOM   862  N NE2 . GLN A 1 110 ? 102.510 73.102  230.687 1.00 93.51  ? 107 GLN A NE2 1 
ATOM   863  N N   . THR A 1 111 ? 102.603 74.139  225.389 1.00 86.04  ? 108 THR A N   1 
ATOM   864  C CA  . THR A 1 111 ? 101.622 74.701  224.478 1.00 86.66  ? 108 THR A CA  1 
ATOM   865  C C   . THR A 1 111 ? 102.252 75.127  223.156 1.00 84.71  ? 108 THR A C   1 
ATOM   866  O O   . THR A 1 111 ? 101.663 75.935  222.442 1.00 88.26  ? 108 THR A O   1 
ATOM   867  C CB  . THR A 1 111 ? 100.901 75.904  225.105 1.00 77.91  ? 108 THR A CB  1 
ATOM   868  O OG1 . THR A 1 111 ? 101.849 76.834  225.647 1.00 75.29  ? 108 THR A OG1 1 
ATOM   869  C CG2 . THR A 1 111 ? 99.952  75.467  226.199 1.00 77.74  ? 108 THR A CG2 1 
ATOM   870  N N   . GLY A 1 112 ? 103.365 74.536  222.750 1.00 82.98  ? 109 GLY A N   1 
ATOM   871  C CA  . GLY A 1 112 ? 104.065 75.002  221.575 1.00 83.45  ? 109 GLY A CA  1 
ATOM   872  C C   . GLY A 1 112 ? 103.728 74.220  220.322 1.00 82.51  ? 109 GLY A C   1 
ATOM   873  O O   . GLY A 1 112 ? 103.402 73.036  220.380 1.00 87.02  ? 109 GLY A O   1 
ATOM   874  N N   . THR A 1 113 ? 103.799 74.916  219.185 1.00 83.60  ? 110 THR A N   1 
ATOM   875  C CA  . THR A 1 113 ? 103.633 74.271  217.889 1.00 90.14  ? 110 THR A CA  1 
ATOM   876  C C   . THR A 1 113 ? 104.589 73.089  217.752 1.00 93.70  ? 110 THR A C   1 
ATOM   877  O O   . THR A 1 113 ? 104.210 72.010  217.267 1.00 91.13  ? 110 THR A O   1 
ATOM   878  C CB  . THR A 1 113 ? 103.864 75.286  216.764 1.00 89.20  ? 110 THR A CB  1 
ATOM   879  O OG1 . THR A 1 113 ? 102.932 76.370  216.902 1.00 90.71  ? 110 THR A OG1 1 
ATOM   880  C CG2 . THR A 1 113 ? 103.689 74.623  215.392 1.00 97.49  ? 110 THR A CG2 1 
ATOM   881  N N   . PHE A 1 114 ? 105.831 73.285  218.195 1.00 89.34  ? 111 PHE A N   1 
ATOM   882  C CA  . PHE A 1 114 ? 106.873 72.302  218.313 1.00 80.79  ? 111 PHE A CA  1 
ATOM   883  C C   . PHE A 1 114 ? 107.187 72.203  219.797 1.00 84.59  ? 111 PHE A C   1 
ATOM   884  O O   . PHE A 1 114 ? 107.370 73.243  220.451 1.00 85.26  ? 111 PHE A O   1 
ATOM   885  C CB  . PHE A 1 114 ? 108.138 72.713  217.515 1.00 75.84  ? 111 PHE A CB  1 
ATOM   886  C CG  . PHE A 1 114 ? 108.147 72.246  216.054 1.00 86.29  ? 111 PHE A CG  1 
ATOM   887  C CD1 . PHE A 1 114 ? 108.375 70.896  215.730 1.00 83.48  ? 111 PHE A CD1 1 
ATOM   888  C CD2 . PHE A 1 114 ? 107.964 73.156  215.003 1.00 78.82  ? 111 PHE A CD2 1 
ATOM   889  C CE1 . PHE A 1 114 ? 108.405 70.458  214.388 1.00 75.56  ? 111 PHE A CE1 1 
ATOM   890  C CE2 . PHE A 1 114 ? 107.995 72.726  213.667 1.00 73.58  ? 111 PHE A CE2 1 
ATOM   891  C CZ  . PHE A 1 114 ? 108.216 71.375  213.362 1.00 75.75  ? 111 PHE A CZ  1 
ATOM   892  N N   . PRO A 1 115 ? 107.143 71.006  220.385 1.00 89.74  ? 112 PRO A N   1 
ATOM   893  C CA  . PRO A 1 115 ? 107.533 70.848  221.792 1.00 82.72  ? 112 PRO A CA  1 
ATOM   894  C C   . PRO A 1 115 ? 108.948 71.352  221.964 1.00 80.60  ? 112 PRO A C   1 
ATOM   895  O O   . PRO A 1 115 ? 109.837 70.971  221.210 1.00 86.19  ? 112 PRO A O   1 
ATOM   896  C CB  . PRO A 1 115 ? 107.449 69.339  222.014 1.00 80.60  ? 112 PRO A CB  1 
ATOM   897  C CG  . PRO A 1 115 ? 107.698 68.765  220.655 1.00 79.50  ? 112 PRO A CG  1 
ATOM   898  C CD  . PRO A 1 115 ? 107.015 69.712  219.702 1.00 87.10  ? 112 PRO A CD  1 
ATOM   899  N N   . MET A 1 116 ? 109.161 72.224  222.934 1.00 75.79  ? 113 MET A N   1 
ATOM   900  C CA  . MET A 1 116 ? 110.478 72.773  223.153 1.00 72.39  ? 113 MET A CA  1 
ATOM   901  C C   . MET A 1 116 ? 110.832 72.824  224.609 1.00 73.69  ? 113 MET A C   1 
ATOM   902  O O   . MET A 1 116 ? 110.019 73.208  225.424 1.00 72.32  ? 113 MET A O   1 
ATOM   903  C CB  . MET A 1 116 ? 110.566 74.184  222.593 1.00 66.76  ? 113 MET A CB  1 
ATOM   904  C CG  . MET A 1 116 ? 111.867 74.889  222.919 1.00 72.72  ? 113 MET A CG  1 
ATOM   905  S SD  . MET A 1 116 ? 111.657 76.668  223.038 1.00 82.59  ? 113 MET A SD  1 
ATOM   906  C CE  . MET A 1 116 ? 109.994 76.846  222.408 1.00 72.90  ? 113 MET A CE  1 
ATOM   907  N N   . VAL A 1 117 ? 112.064 72.475  224.937 1.00 72.57  ? 114 VAL A N   1 
ATOM   908  C CA  . VAL A 1 117 ? 112.497 72.570  226.310 1.00 66.52  ? 114 VAL A CA  1 
ATOM   909  C C   . VAL A 1 117 ? 113.408 73.756  226.494 1.00 64.80  ? 114 VAL A C   1 
ATOM   910  O O   . VAL A 1 117 ? 114.510 73.782  225.967 1.00 65.12  ? 114 VAL A O   1 
ATOM   911  C CB  . VAL A 1 117 ? 113.216 71.305  226.768 1.00 65.57  ? 114 VAL A CB  1 
ATOM   912  C CG1 . VAL A 1 117 ? 113.503 71.376  228.255 1.00 66.31  ? 114 VAL A CG1 1 
ATOM   913  C CG2 . VAL A 1 117 ? 112.382 70.081  226.445 1.00 68.15  ? 114 VAL A CG2 1 
ATOM   914  N N   . PHE A 1 118 ? 112.942 74.744  227.229 1.00 65.10  ? 115 PHE A N   1 
ATOM   915  C CA  . PHE A 1 118 ? 113.728 75.941  227.515 1.00 61.07  ? 115 PHE A CA  1 
ATOM   916  C C   . PHE A 1 118 ? 114.962 75.578  228.335 1.00 61.30  ? 115 PHE A C   1 
ATOM   917  O O   . PHE A 1 118 ? 114.904 74.691  229.198 1.00 61.64  ? 115 PHE A O   1 
ATOM   918  C CB  . PHE A 1 118 ? 112.903 76.986  228.267 1.00 57.59  ? 115 PHE A CB  1 
ATOM   919  C CG  . PHE A 1 118 ? 111.901 77.675  227.417 1.00 60.12  ? 115 PHE A CG  1 
ATOM   920  C CD1 . PHE A 1 118 ? 112.307 78.426  226.320 1.00 67.43  ? 115 PHE A CD1 1 
ATOM   921  C CD2 . PHE A 1 118 ? 110.556 77.563  227.689 1.00 62.59  ? 115 PHE A CD2 1 
ATOM   922  C CE1 . PHE A 1 118 ? 111.385 79.063  225.494 1.00 65.48  ? 115 PHE A CE1 1 
ATOM   923  C CE2 . PHE A 1 118 ? 109.621 78.194  226.879 1.00 72.24  ? 115 PHE A CE2 1 
ATOM   924  C CZ  . PHE A 1 118 ? 110.037 78.947  225.774 1.00 72.45  ? 115 PHE A CZ  1 
ATOM   925  N N   . PRO A 1 119 ? 116.086 76.236  228.092 1.00 58.35  ? 116 PRO A N   1 
ATOM   926  C CA  . PRO A 1 119 ? 117.329 75.832  228.757 1.00 57.80  ? 116 PRO A CA  1 
ATOM   927  C C   . PRO A 1 119 ? 117.343 76.194  230.234 1.00 54.87  ? 116 PRO A C   1 
ATOM   928  O O   . PRO A 1 119 ? 116.804 77.223  230.658 1.00 55.50  ? 116 PRO A O   1 
ATOM   929  C CB  . PRO A 1 119 ? 118.407 76.597  227.977 1.00 58.98  ? 116 PRO A CB  1 
ATOM   930  C CG  . PRO A 1 119 ? 117.693 77.787  227.402 1.00 54.64  ? 116 PRO A CG  1 
ATOM   931  C CD  . PRO A 1 119 ? 116.286 77.325  227.121 1.00 53.51  ? 116 PRO A CD  1 
ATOM   932  N N   . ALA A 1 120 ? 117.981 75.322  231.020 1.00 57.33  ? 117 ALA A N   1 
ATOM   933  C CA  . ALA A 1 120 ? 118.201 75.610  232.429 1.00 55.95  ? 117 ALA A CA  1 
ATOM   934  C C   . ALA A 1 120 ? 119.004 76.891  232.568 1.00 57.07  ? 117 ALA A C   1 
ATOM   935  O O   . ALA A 1 120 ? 119.817 77.231  231.707 1.00 56.98  ? 117 ALA A O   1 
ATOM   936  C CB  . ALA A 1 120 ? 118.933 74.462  233.107 1.00 55.00  ? 117 ALA A CB  1 
ATOM   937  N N   . TYR A 1 121 ? 118.779 77.600  233.670 1.00 55.66  ? 118 TYR A N   1 
ATOM   938  C CA  . TYR A 1 121 ? 119.394 78.907  233.841 1.00 53.16  ? 118 TYR A CA  1 
ATOM   939  C C   . TYR A 1 121 ? 120.919 78.785  233.861 1.00 52.98  ? 118 TYR A C   1 
ATOM   940  O O   . TYR A 1 121 ? 121.471 77.729  234.170 1.00 59.96  ? 118 TYR A O   1 
ATOM   941  C CB  . TYR A 1 121 ? 118.877 79.562  235.125 1.00 55.47  ? 118 TYR A CB  1 
ATOM   942  C CG  . TYR A 1 121 ? 117.373 79.860  235.150 1.00 54.18  ? 118 TYR A CG  1 
ATOM   943  C CD1 . TYR A 1 121 ? 116.525 79.396  234.157 1.00 53.77  ? 118 TYR A CD1 1 
ATOM   944  C CD2 . TYR A 1 121 ? 116.820 80.685  236.132 1.00 53.78  ? 118 TYR A CD2 1 
ATOM   945  C CE1 . TYR A 1 121 ? 115.168 79.691  234.172 1.00 56.59  ? 118 TYR A CE1 1 
ATOM   946  C CE2 . TYR A 1 121 ? 115.454 80.996  236.148 1.00 49.32  ? 118 TYR A CE2 1 
ATOM   947  C CZ  . TYR A 1 121 ? 114.636 80.492  235.165 1.00 52.92  ? 118 TYR A CZ  1 
ATOM   948  O OH  . TYR A 1 121 ? 113.285 80.782  235.147 1.00 51.03  ? 118 TYR A OH  1 
ATOM   949  N N   . ARG A 1 122 ? 121.612 79.854  233.470 1.00 52.17  ? 119 ARG A N   1 
ATOM   950  C CA  . ARG A 1 122 ? 123.071 79.907  233.566 1.00 58.51  ? 119 ARG A CA  1 
ATOM   951  C C   . ARG A 1 122 ? 123.507 81.019  234.512 1.00 64.02  ? 119 ARG A C   1 
ATOM   952  O O   . ARG A 1 122 ? 122.862 82.067  234.602 1.00 64.92  ? 119 ARG A O   1 
ATOM   953  C CB  . ARG A 1 122 ? 123.752 80.103  232.199 1.00 49.70  ? 119 ARG A CB  1 
ATOM   954  C CG  . ARG A 1 122 ? 123.580 81.444  231.560 1.00 55.11  ? 119 ARG A CG  1 
ATOM   955  C CD  . ARG A 1 122 ? 124.136 81.438  230.128 1.00 59.83  ? 119 ARG A CD  1 
ATOM   956  N NE  . ARG A 1 122 ? 123.693 82.610  229.377 1.00 60.72  ? 119 ARG A NE  1 
ATOM   957  C CZ  . ARG A 1 122 ? 124.397 83.719  229.198 1.00 60.84  ? 119 ARG A CZ  1 
ATOM   958  N NH1 . ARG A 1 122 ? 125.627 83.844  229.670 1.00 67.96  ? 119 ARG A NH1 1 
ATOM   959  N NH2 . ARG A 1 122 ? 123.843 84.740  228.552 1.00 58.88  ? 119 ARG A NH2 1 
ATOM   960  N N   . LYS A 1 123 ? 124.577 80.781  235.257 1.00 62.64  ? 120 LYS A N   1 
ATOM   961  C CA  . LYS A 1 123 ? 125.043 81.828  236.150 1.00 65.27  ? 120 LYS A CA  1 
ATOM   962  C C   . LYS A 1 123 ? 125.916 82.818  235.386 1.00 68.39  ? 120 LYS A C   1 
ATOM   963  O O   . LYS A 1 123 ? 126.565 82.473  234.391 1.00 63.77  ? 120 LYS A O   1 
ATOM   964  C CB  . LYS A 1 123 ? 125.825 81.258  237.326 1.00 61.35  ? 120 LYS A CB  1 
ATOM   965  C CG  . LYS A 1 123 ? 126.330 82.322  238.247 1.00 60.58  ? 120 LYS A CG  1 
ATOM   966  C CD  . LYS A 1 123 ? 127.202 81.722  239.293 1.00 71.22  ? 120 LYS A CD  1 
ATOM   967  C CE  . LYS A 1 123 ? 128.161 82.763  239.789 1.00 70.98  ? 120 LYS A CE  1 
ATOM   968  N NZ  . LYS A 1 123 ? 129.136 82.122  240.679 1.00 75.92  ? 120 LYS A NZ  1 
ATOM   969  N N   . LEU A 1 124 ? 125.851 84.077  235.805 1.00 68.68  ? 121 LEU A N   1 
ATOM   970  C CA  . LEU A 1 124 ? 126.738 85.120  235.312 1.00 67.89  ? 121 LEU A CA  1 
ATOM   971  C C   . LEU A 1 124 ? 127.814 85.426  236.354 1.00 73.23  ? 121 LEU A C   1 
ATOM   972  O O   . LEU A 1 124 ? 127.515 85.604  237.541 1.00 72.77  ? 121 LEU A O   1 
ATOM   973  C CB  . LEU A 1 124 ? 125.950 86.378  234.954 1.00 67.28  ? 121 LEU A CB  1 
ATOM   974  C CG  . LEU A 1 124 ? 124.864 86.202  233.891 1.00 69.43  ? 121 LEU A CG  1 
ATOM   975  C CD1 . LEU A 1 124 ? 124.104 87.502  233.685 1.00 65.31  ? 121 LEU A CD1 1 
ATOM   976  C CD2 . LEU A 1 124 ? 125.474 85.731  232.578 1.00 66.29  ? 121 LEU A CD2 1 
ATOM   977  N N   . ASP A 1 125 ? 129.051 85.521  235.873 1.00 76.84  ? 122 ASP A N   1 
ATOM   978  C CA  . ASP A 1 125 ? 130.168 85.887  236.714 1.00 78.74  ? 122 ASP A CA  1 
ATOM   979  C C   . ASP A 1 125 ? 130.417 87.314  236.343 1.00 78.36  ? 122 ASP A C   1 
ATOM   980  O O   . ASP A 1 125 ? 130.811 87.610  235.222 1.00 77.27  ? 122 ASP A O   1 
ATOM   981  C CB  . ASP A 1 125 ? 131.382 85.039  236.389 1.00 80.84  ? 122 ASP A CB  1 
ATOM   982  C CG  . ASP A 1 125 ? 132.641 85.549  237.044 1.00 88.59  ? 122 ASP A CG  1 
ATOM   983  O OD1 . ASP A 1 125 ? 132.550 86.091  238.164 1.00 84.74  ? 122 ASP A OD1 1 
ATOM   984  O OD2 . ASP A 1 125 ? 133.721 85.400  236.441 1.00 84.44  ? 122 ASP A OD2 1 
ATOM   985  N N   . LEU A 1 126 ? 130.215 88.212  237.280 1.00 75.17  ? 123 LEU A N   1 
ATOM   986  C CA  . LEU A 1 126 ? 130.295 89.631  236.958 1.00 71.75  ? 123 LEU A CA  1 
ATOM   987  C C   . LEU A 1 126 ? 131.680 90.043  236.490 1.00 74.94  ? 123 LEU A C   1 
ATOM   988  O O   . LEU A 1 126 ? 131.837 91.129  235.910 1.00 72.03  ? 123 LEU A O   1 
ATOM   989  C CB  . LEU A 1 126 ? 129.885 90.465  238.162 1.00 69.44  ? 123 LEU A CB  1 
ATOM   990  C CG  . LEU A 1 126 ? 128.485 91.047  238.128 1.00 72.91  ? 123 LEU A CG  1 
ATOM   991  C CD1 . LEU A 1 126 ? 128.075 91.409  239.534 1.00 78.51  ? 123 LEU A CD1 1 
ATOM   992  C CD2 . LEU A 1 126 ? 128.497 92.305  237.249 1.00 63.77  ? 123 LEU A CD2 1 
ATOM   993  N N   . ARG A 1 127 ? 132.666 89.182  236.653 1.00 74.09  ? 124 ARG A N   1 
ATOM   994  C CA  . ARG A 1 127 ? 134.031 89.543  236.302 1.00 71.11  ? 124 ARG A CA  1 
ATOM   995  C C   . ARG A 1 127 ? 134.199 89.766  234.831 1.00 73.29  ? 124 ARG A C   1 
ATOM   996  O O   . ARG A 1 127 ? 135.143 90.408  234.404 1.00 78.85  ? 124 ARG A O   1 
ATOM   997  C CB  . ARG A 1 127 ? 134.968 88.432  236.749 1.00 70.69  ? 124 ARG A CB  1 
ATOM   998  C CG  . ARG A 1 127 ? 135.113 88.343  238.257 1.00 81.55  ? 124 ARG A CG  1 
ATOM   999  C CD  . ARG A 1 127 ? 135.581 86.968  238.696 1.00 78.91  ? 124 ARG A CD  1 
ATOM   1000 N NE  . ARG A 1 127 ? 136.613 86.437  237.817 1.00 79.82  ? 124 ARG A NE  1 
ATOM   1001 C CZ  . ARG A 1 127 ? 136.668 85.176  237.411 1.00 78.31  ? 124 ARG A CZ  1 
ATOM   1002 N NH1 . ARG A 1 127 ? 135.745 84.311  237.800 1.00 73.66  ? 124 ARG A NH1 1 
ATOM   1003 N NH2 . ARG A 1 127 ? 137.645 84.780  236.612 1.00 81.63  ? 124 ARG A NH2 1 
ATOM   1004 N N   . HIS A 1 128 ? 133.286 89.244  234.044 1.00 78.64  ? 125 HIS A N   1 
ATOM   1005 C CA  . HIS A 1 128 ? 133.390 89.330  232.591 1.00 78.28  ? 125 HIS A CA  1 
ATOM   1006 C C   . HIS A 1 128 ? 132.952 90.676  232.015 1.00 77.64  ? 125 HIS A C   1 
ATOM   1007 O O   . HIS A 1 128 ? 133.267 90.962  230.853 1.00 71.46  ? 125 HIS A O   1 
ATOM   1008 C CB  . HIS A 1 128 ? 132.532 88.249  231.928 1.00 79.49  ? 125 HIS A CB  1 
ATOM   1009 C CG  . HIS A 1 128 ? 133.056 86.851  232.066 1.00 84.30  ? 125 HIS A CG  1 
ATOM   1010 N ND1 . HIS A 1 128 ? 132.833 86.079  233.189 1.00 90.82  ? 125 HIS A ND1 1 
ATOM   1011 C CD2 . HIS A 1 128 ? 133.736 86.063  231.199 1.00 85.02  ? 125 HIS A CD2 1 
ATOM   1012 C CE1 . HIS A 1 128 ? 133.380 84.887  233.019 1.00 97.13  ? 125 HIS A CE1 1 
ATOM   1013 N NE2 . HIS A 1 128 ? 133.931 84.850  231.818 1.00 93.50  ? 125 HIS A NE2 1 
ATOM   1014 N N   . TYR A 1 129 ? 132.207 91.489  232.759 1.00 77.13  ? 126 TYR A N   1 
ATOM   1015 C CA  . TYR A 1 129 ? 131.536 92.630  232.154 1.00 77.43  ? 126 TYR A CA  1 
ATOM   1016 C C   . TYR A 1 129 ? 132.036 93.945  232.745 1.00 76.59  ? 126 TYR A C   1 
ATOM   1017 O O   . TYR A 1 129 ? 132.360 94.028  233.931 1.00 86.45  ? 126 TYR A O   1 
ATOM   1018 C CB  . TYR A 1 129 ? 130.004 92.501  232.327 1.00 76.96  ? 126 TYR A CB  1 
ATOM   1019 C CG  . TYR A 1 129 ? 129.426 91.148  231.900 1.00 72.07  ? 126 TYR A CG  1 
ATOM   1020 C CD1 . TYR A 1 129 ? 129.149 90.867  230.567 1.00 75.65  ? 126 TYR A CD1 1 
ATOM   1021 C CD2 . TYR A 1 129 ? 129.155 90.163  232.833 1.00 72.74  ? 126 TYR A CD2 1 
ATOM   1022 C CE1 . TYR A 1 129 ? 128.628 89.637  230.178 1.00 74.50  ? 126 TYR A CE1 1 
ATOM   1023 C CE2 . TYR A 1 129 ? 128.626 88.937  232.457 1.00 77.33  ? 126 TYR A CE2 1 
ATOM   1024 C CZ  . TYR A 1 129 ? 128.366 88.673  231.131 1.00 77.04  ? 126 TYR A CZ  1 
ATOM   1025 O OH  . TYR A 1 129 ? 127.840 87.440  230.765 1.00 78.51  ? 126 TYR A OH  1 
ATOM   1026 N N   . ASP A 1 130 ? 132.073 94.978  231.904 1.00 76.66  ? 127 ASP A N   1 
ATOM   1027 C CA  . ASP A 1 130 ? 132.477 96.334  232.276 1.00 79.62  ? 127 ASP A CA  1 
ATOM   1028 C C   . ASP A 1 130 ? 131.879 97.315  231.262 1.00 80.24  ? 127 ASP A C   1 
ATOM   1029 O O   . ASP A 1 130 ? 131.041 96.942  230.436 1.00 82.19  ? 127 ASP A O   1 
ATOM   1030 C CB  . ASP A 1 130 ? 134.002 96.422  232.364 1.00 82.71  ? 127 ASP A CB  1 
ATOM   1031 C CG  . ASP A 1 130 ? 134.689 96.001  231.076 1.00 87.40  ? 127 ASP A CG  1 
ATOM   1032 O OD1 . ASP A 1 130 ? 134.192 96.331  229.966 1.00 81.30  ? 127 ASP A OD1 1 
ATOM   1033 O OD2 . ASP A 1 130 ? 135.718 95.296  231.181 1.00 89.21  ? 127 ASP A OD2 1 
ATOM   1034 N N   . ASP A 1 131 ? 132.355 98.561  231.268 1.00 78.98  ? 128 ASP A N   1 
ATOM   1035 C CA  . ASP A 1 131 ? 131.651 99.583  230.497 1.00 82.43  ? 128 ASP A CA  1 
ATOM   1036 C C   . ASP A 1 131 ? 131.820 99.446  228.995 1.00 84.98  ? 128 ASP A C   1 
ATOM   1037 O O   . ASP A 1 131 ? 131.090 100.113 228.256 1.00 87.16  ? 128 ASP A O   1 
ATOM   1038 C CB  . ASP A 1 131 ? 132.071 100.986 230.923 1.00 84.34  ? 128 ASP A CB  1 
ATOM   1039 C CG  . ASP A 1 131 ? 131.758 101.264 232.370 1.00 92.94  ? 128 ASP A CG  1 
ATOM   1040 O OD1 . ASP A 1 131 ? 132.396 100.645 233.255 1.00 96.00  ? 128 ASP A OD1 1 
ATOM   1041 O OD2 . ASP A 1 131 ? 130.854 102.096 232.616 1.00 97.15  ? 128 ASP A OD2 1 
ATOM   1042 N N   . ALA A 1 132 ? 132.754 98.624  228.523 1.00 83.49  ? 129 ALA A N   1 
ATOM   1043 C CA  . ALA A 1 132 ? 132.833 98.372  227.092 1.00 84.84  ? 129 ALA A CA  1 
ATOM   1044 C C   . ALA A 1 132 ? 132.046 97.139  226.688 1.00 85.64  ? 129 ALA A C   1 
ATOM   1045 O O   . ALA A 1 132 ? 131.644 97.027  225.523 1.00 89.89  ? 129 ALA A O   1 
ATOM   1046 C CB  . ALA A 1 132 ? 134.289 98.210  226.647 1.00 86.11  ? 129 ALA A CB  1 
ATOM   1047 N N   . LEU A 1 133 ? 131.813 96.228  227.629 1.00 82.25  ? 130 LEU A N   1 
ATOM   1048 C CA  . LEU A 1 133 ? 131.029 95.015  227.400 1.00 76.18  ? 130 LEU A CA  1 
ATOM   1049 C C   . LEU A 1 133 ? 130.083 94.821  228.571 1.00 75.29  ? 130 LEU A C   1 
ATOM   1050 O O   . LEU A 1 133 ? 130.257 93.899  229.376 1.00 75.51  ? 130 LEU A O   1 
ATOM   1051 C CB  . LEU A 1 133 ? 131.949 93.804  227.266 1.00 72.40  ? 130 LEU A CB  1 
ATOM   1052 C CG  . LEU A 1 133 ? 131.389 92.554  226.618 1.00 72.23  ? 130 LEU A CG  1 
ATOM   1053 C CD1 . LEU A 1 133 ? 131.414 92.710  225.118 1.00 76.48  ? 130 LEU A CD1 1 
ATOM   1054 C CD2 . LEU A 1 133 ? 132.187 91.363  227.050 1.00 74.76  ? 130 LEU A CD2 1 
ATOM   1055 N N   . PRO A 1 134 ? 129.061 95.665  228.701 1.00 67.45  ? 131 PRO A N   1 
ATOM   1056 C CA  . PRO A 1 134 ? 128.257 95.646  229.925 1.00 68.92  ? 131 PRO A CA  1 
ATOM   1057 C C   . PRO A 1 134 ? 127.540 94.318  230.137 1.00 72.64  ? 131 PRO A C   1 
ATOM   1058 O O   . PRO A 1 134 ? 127.541 93.423  229.290 1.00 76.89  ? 131 PRO A O   1 
ATOM   1059 C CB  . PRO A 1 134 ? 127.268 96.797  229.704 1.00 66.89  ? 131 PRO A CB  1 
ATOM   1060 C CG  . PRO A 1 134 ? 127.226 97.009  228.281 1.00 60.90  ? 131 PRO A CG  1 
ATOM   1061 C CD  . PRO A 1 134 ? 128.615 96.724  227.791 1.00 67.28  ? 131 PRO A CD  1 
ATOM   1062 N N   . LEU A 1 135 ? 126.921 94.197  231.316 1.00 68.88  ? 132 LEU A N   1 
ATOM   1063 C CA  . LEU A 1 135 ? 126.175 92.989  231.671 1.00 68.86  ? 132 LEU A CA  1 
ATOM   1064 C C   . LEU A 1 135 ? 125.013 92.730  230.714 1.00 68.25  ? 132 LEU A C   1 
ATOM   1065 O O   . LEU A 1 135 ? 124.691 91.569  230.423 1.00 63.08  ? 132 LEU A O   1 
ATOM   1066 C CB  . LEU A 1 135 ? 125.667 93.121  233.116 1.00 68.53  ? 132 LEU A CB  1 
ATOM   1067 C CG  . LEU A 1 135 ? 124.738 92.100  233.796 1.00 63.62  ? 132 LEU A CG  1 
ATOM   1068 C CD1 . LEU A 1 135 ? 125.406 90.757  234.050 1.00 63.98  ? 132 LEU A CD1 1 
ATOM   1069 C CD2 . LEU A 1 135 ? 124.207 92.682  235.081 1.00 57.17  ? 132 LEU A CD2 1 
ATOM   1070 N N   . SER A 1 136 ? 124.401 93.797  230.187 1.00 68.56  ? 133 SER A N   1 
ATOM   1071 C CA  . SER A 1 136 ? 123.292 93.650  229.252 1.00 70.02  ? 133 SER A CA  1 
ATOM   1072 C C   . SER A 1 136 ? 123.697 92.905  227.984 1.00 72.57  ? 133 SER A C   1 
ATOM   1073 O O   . SER A 1 136 ? 122.821 92.439  227.243 1.00 71.81  ? 133 SER A O   1 
ATOM   1074 C CB  . SER A 1 136 ? 122.739 95.030  228.875 1.00 72.44  ? 133 SER A CB  1 
ATOM   1075 O OG  . SER A 1 136 ? 123.742 95.850  228.293 1.00 72.41  ? 133 SER A OG  1 
ATOM   1076 N N   . THR A 1 137 ? 124.999 92.764  227.720 1.00 70.64  ? 134 THR A N   1 
ATOM   1077 C CA  . THR A 1 137 ? 125.407 91.972  226.575 1.00 66.54  ? 134 THR A CA  1 
ATOM   1078 C C   . THR A 1 137 ? 125.067 90.507  226.767 1.00 64.68  ? 134 THR A C   1 
ATOM   1079 O O   . THR A 1 137 ? 125.082 89.756  225.786 1.00 70.32  ? 134 THR A O   1 
ATOM   1080 C CB  . THR A 1 137 ? 126.903 92.125  226.306 1.00 68.50  ? 134 THR A CB  1 
ATOM   1081 O OG1 . THR A 1 137 ? 127.641 91.653  227.437 1.00 69.99  ? 134 THR A OG1 1 
ATOM   1082 C CG2 . THR A 1 137 ? 127.247 93.579  226.060 1.00 67.75  ? 134 THR A CG2 1 
ATOM   1083 N N   . ALA A 1 138 ? 124.760 90.080  227.997 1.00 62.53  ? 135 ALA A N   1 
ATOM   1084 C CA  . ALA A 1 138 ? 124.326 88.702  228.211 1.00 65.25  ? 135 ALA A CA  1 
ATOM   1085 C C   . ALA A 1 138 ? 122.946 88.412  227.611 1.00 63.68  ? 135 ALA A C   1 
ATOM   1086 O O   . ALA A 1 138 ? 122.544 87.244  227.557 1.00 60.98  ? 135 ALA A O   1 
ATOM   1087 C CB  . ALA A 1 138 ? 124.342 88.368  229.702 1.00 57.35  ? 135 ALA A CB  1 
ATOM   1088 N N   . LEU A 1 139 ? 122.211 89.428  227.161 1.00 56.30  ? 136 LEU A N   1 
ATOM   1089 C CA  . LEU A 1 139 ? 120.991 89.204  226.407 1.00 56.49  ? 136 LEU A CA  1 
ATOM   1090 C C   . LEU A 1 139 ? 121.164 89.490  224.923 1.00 60.72  ? 136 LEU A C   1 
ATOM   1091 O O   . LEU A 1 139 ? 120.183 89.444  224.167 1.00 59.76  ? 136 LEU A O   1 
ATOM   1092 C CB  . LEU A 1 139 ? 119.853 90.048  226.965 1.00 55.89  ? 136 LEU A CB  1 
ATOM   1093 C CG  . LEU A 1 139 ? 119.417 89.695  228.373 1.00 56.29  ? 136 LEU A CG  1 
ATOM   1094 C CD1 . LEU A 1 139 ? 118.138 90.430  228.647 1.00 58.77  ? 136 LEU A CD1 1 
ATOM   1095 C CD2 . LEU A 1 139 ? 119.253 88.199  228.559 1.00 57.24  ? 136 LEU A CD2 1 
ATOM   1096 N N   . GLY A 1 140 ? 122.386 89.777  224.495 1.00 61.35  ? 137 GLY A N   1 
ATOM   1097 C CA  . GLY A 1 140 ? 122.681 90.125  223.126 1.00 59.62  ? 137 GLY A CA  1 
ATOM   1098 C C   . GLY A 1 140 ? 123.943 89.445  222.650 1.00 61.86  ? 137 GLY A C   1 
ATOM   1099 O O   . GLY A 1 140 ? 123.958 88.226  222.466 1.00 62.89  ? 137 GLY A O   1 
ATOM   1100 N N   . VAL A 1 141 ? 125.024 90.210  222.479 1.00 62.39  ? 138 VAL A N   1 
ATOM   1101 C CA  . VAL A 1 141 ? 126.228 89.653  221.869 1.00 63.95  ? 138 VAL A CA  1 
ATOM   1102 C C   . VAL A 1 141 ? 126.923 88.629  222.769 1.00 68.93  ? 138 VAL A C   1 
ATOM   1103 O O   . VAL A 1 141 ? 127.720 87.817  222.272 1.00 66.58  ? 138 VAL A O   1 
ATOM   1104 C CB  . VAL A 1 141 ? 127.182 90.789  221.461 1.00 61.81  ? 138 VAL A CB  1 
ATOM   1105 C CG1 . VAL A 1 141 ? 127.771 91.468  222.703 1.00 71.40  ? 138 VAL A CG1 1 
ATOM   1106 C CG2 . VAL A 1 141 ? 128.259 90.264  220.536 1.00 56.30  ? 138 VAL A CG2 1 
ATOM   1107 N N   . MET A 1 142 ? 126.671 88.657  224.083 1.00 62.33  ? 139 MET A N   1 
ATOM   1108 C CA  . MET A 1 142 ? 127.207 87.659  225.000 1.00 64.10  ? 139 MET A CA  1 
ATOM   1109 C C   . MET A 1 142 ? 126.107 86.746  225.533 1.00 64.91  ? 139 MET A C   1 
ATOM   1110 O O   . MET A 1 142 ? 126.222 86.190  226.635 1.00 67.13  ? 139 MET A O   1 
ATOM   1111 C CB  . MET A 1 142 ? 127.938 88.319  226.168 1.00 70.25  ? 139 MET A CB  1 
ATOM   1112 C CG  . MET A 1 142 ? 129.198 89.070  225.811 1.00 70.63  ? 139 MET A CG  1 
ATOM   1113 S SD  . MET A 1 142 ? 130.543 87.978  225.343 1.00 75.63  ? 139 MET A SD  1 
ATOM   1114 C CE  . MET A 1 142 ? 130.682 88.353  223.585 1.00 73.17  ? 139 MET A CE  1 
ATOM   1115 N N   . GLY A 1 143 ? 125.044 86.581  224.763 1.00 58.85  ? 140 GLY A N   1 
ATOM   1116 C CA  . GLY A 1 143 ? 123.940 85.711  225.146 1.00 61.00  ? 140 GLY A CA  1 
ATOM   1117 C C   . GLY A 1 143 ? 123.288 85.085  223.947 1.00 58.79  ? 140 GLY A C   1 
ATOM   1118 O O   . GLY A 1 143 ? 123.974 84.666  223.006 1.00 58.67  ? 140 GLY A O   1 
ATOM   1119 N N   . GLY A 1 144 ? 121.959 84.992  223.984 1.00 59.28  ? 141 GLY A N   1 
ATOM   1120 C CA  . GLY A 1 144 ? 121.180 84.345  222.958 1.00 56.73  ? 141 GLY A CA  1 
ATOM   1121 C C   . GLY A 1 144 ? 121.558 84.756  221.552 1.00 61.44  ? 141 GLY A C   1 
ATOM   1122 O O   . GLY A 1 144 ? 121.960 83.921  220.728 1.00 61.52  ? 141 GLY A O   1 
ATOM   1123 N N   . PRO A 1 145 ? 121.472 86.057  221.252 1.00 62.48  ? 142 PRO A N   1 
ATOM   1124 C CA  . PRO A 1 145 ? 121.775 86.495  219.874 1.00 61.24  ? 142 PRO A CA  1 
ATOM   1125 C C   . PRO A 1 145 ? 123.209 86.218  219.440 1.00 57.58  ? 142 PRO A C   1 
ATOM   1126 O O   . PRO A 1 145 ? 123.418 85.650  218.363 1.00 54.72  ? 142 PRO A O   1 
ATOM   1127 C CB  . PRO A 1 145 ? 121.461 87.996  219.923 1.00 55.24  ? 142 PRO A CB  1 
ATOM   1128 C CG  . PRO A 1 145 ? 120.488 88.129  220.988 1.00 56.69  ? 142 PRO A CG  1 
ATOM   1129 C CD  . PRO A 1 145 ? 120.896 87.151  222.044 1.00 58.66  ? 142 PRO A CD  1 
ATOM   1130 N N   . GLY A 1 146 ? 124.200 86.563  220.267 1.00 54.73  ? 143 GLY A N   1 
ATOM   1131 C CA  . GLY A 1 146 ? 125.581 86.283  219.910 1.00 54.55  ? 143 GLY A CA  1 
ATOM   1132 C C   . GLY A 1 146 ? 125.869 84.802  219.746 1.00 58.31  ? 143 GLY A C   1 
ATOM   1133 O O   . GLY A 1 146 ? 126.647 84.407  218.873 1.00 55.11  ? 143 GLY A O   1 
ATOM   1134 N N   . MET A 1 147 ? 125.258 83.963  220.594 1.00 60.45  ? 144 MET A N   1 
ATOM   1135 C CA  . MET A 1 147 ? 125.425 82.515  220.471 1.00 58.25  ? 144 MET A CA  1 
ATOM   1136 C C   . MET A 1 147 ? 124.828 81.987  219.175 1.00 56.07  ? 144 MET A C   1 
ATOM   1137 O O   . MET A 1 147 ? 125.373 81.060  218.567 1.00 53.18  ? 144 MET A O   1 
ATOM   1138 C CB  . MET A 1 147 ? 124.798 81.801  221.663 1.00 56.78  ? 144 MET A CB  1 
ATOM   1139 C CG  . MET A 1 147 ? 124.894 80.306  221.559 1.00 57.28  ? 144 MET A CG  1 
ATOM   1140 S SD  . MET A 1 147 ? 126.611 79.798  221.538 1.00 63.12  ? 144 MET A SD  1 
ATOM   1141 C CE  . MET A 1 147 ? 126.982 80.064  223.274 1.00 56.93  ? 144 MET A CE  1 
ATOM   1142 N N   . THR A 1 148 ? 123.693 82.538  218.751 1.00 56.97  ? 145 THR A N   1 
ATOM   1143 C CA  . THR A 1 148 ? 123.160 82.176  217.443 1.00 62.75  ? 145 THR A CA  1 
ATOM   1144 C C   . THR A 1 148 ? 124.184 82.477  216.344 1.00 58.22  ? 145 THR A C   1 
ATOM   1145 O O   . THR A 1 148 ? 124.608 81.578  215.610 1.00 57.14  ? 145 THR A O   1 
ATOM   1146 C CB  . THR A 1 148 ? 121.837 82.906  217.188 1.00 62.51  ? 145 THR A CB  1 
ATOM   1147 O OG1 . THR A 1 148 ? 120.929 82.639  218.257 1.00 62.06  ? 145 THR A OG1 1 
ATOM   1148 C CG2 . THR A 1 148 ? 121.190 82.412  215.915 1.00 55.68  ? 145 THR A CG2 1 
ATOM   1149 N N   . ALA A 1 149 ? 124.624 83.734  216.243 1.00 55.09  ? 146 ALA A N   1 
ATOM   1150 C CA  . ALA A 1 149 ? 125.550 84.128  215.179 1.00 58.14  ? 146 ALA A CA  1 
ATOM   1151 C C   . ALA A 1 149 ? 126.865 83.359  215.258 1.00 60.51  ? 146 ALA A C   1 
ATOM   1152 O O   . ALA A 1 149 ? 127.280 82.707  214.294 1.00 59.49  ? 146 ALA A O   1 
ATOM   1153 C CB  . ALA A 1 149 ? 125.819 85.629  215.237 1.00 59.99  ? 146 ALA A CB  1 
ATOM   1154 N N   . TRP A 1 150 ? 127.535 83.424  216.409 1.00 62.56  ? 147 TRP A N   1 
ATOM   1155 C CA  . TRP A 1 150 ? 128.814 82.737  216.570 1.00 60.51  ? 147 TRP A CA  1 
ATOM   1156 C C   . TRP A 1 150 ? 128.681 81.237  216.314 1.00 61.22  ? 147 TRP A C   1 
ATOM   1157 O O   . TRP A 1 150 ? 129.532 80.636  215.650 1.00 59.98  ? 147 TRP A O   1 
ATOM   1158 C CB  . TRP A 1 150 ? 129.345 83.003  217.982 1.00 60.00  ? 147 TRP A CB  1 
ATOM   1159 C CG  . TRP A 1 150 ? 130.571 82.246  218.359 1.00 61.80  ? 147 TRP A CG  1 
ATOM   1160 C CD1 . TRP A 1 150 ? 131.862 82.640  218.177 1.00 60.68  ? 147 TRP A CD1 1 
ATOM   1161 C CD2 . TRP A 1 150 ? 130.626 80.968  219.004 1.00 61.80  ? 147 TRP A CD2 1 
ATOM   1162 N NE1 . TRP A 1 150 ? 132.718 81.680  218.657 1.00 64.39  ? 147 TRP A NE1 1 
ATOM   1163 C CE2 . TRP A 1 150 ? 131.984 80.643  219.168 1.00 61.84  ? 147 TRP A CE2 1 
ATOM   1164 C CE3 . TRP A 1 150 ? 129.660 80.069  219.455 1.00 61.48  ? 147 TRP A CE3 1 
ATOM   1165 C CZ2 . TRP A 1 150 ? 132.399 79.457  219.755 1.00 60.22  ? 147 TRP A CZ2 1 
ATOM   1166 C CZ3 . TRP A 1 150 ? 130.076 78.890  220.035 1.00 62.66  ? 147 TRP A CZ3 1 
ATOM   1167 C CH2 . TRP A 1 150 ? 131.433 78.596  220.181 1.00 61.70  ? 147 TRP A CH2 1 
ATOM   1168 N N   . GLY A 1 151 ? 127.589 80.629  216.786 1.00 62.40  ? 148 GLY A N   1 
ATOM   1169 C CA  . GLY A 1 151 ? 127.407 79.199  216.598 1.00 56.53  ? 148 GLY A CA  1 
ATOM   1170 C C   . GLY A 1 151 ? 127.341 78.809  215.136 1.00 59.54  ? 148 GLY A C   1 
ATOM   1171 O O   . GLY A 1 151 ? 128.003 77.864  214.703 1.00 62.54  ? 148 GLY A O   1 
ATOM   1172 N N   . THR A 1 152 ? 126.546 79.539  214.351 1.00 58.93  ? 149 THR A N   1 
ATOM   1173 C CA  . THR A 1 152 ? 126.366 79.191  212.942 1.00 59.07  ? 149 THR A CA  1 
ATOM   1174 C C   . THR A 1 152 ? 127.664 79.317  212.151 1.00 61.56  ? 149 THR A C   1 
ATOM   1175 O O   . THR A 1 152 ? 127.940 78.497  211.265 1.00 59.30  ? 149 THR A O   1 
ATOM   1176 C CB  . THR A 1 152 ? 125.285 80.063  212.312 1.00 57.91  ? 149 THR A CB  1 
ATOM   1177 O OG1 . THR A 1 152 ? 124.080 79.963  213.078 1.00 55.46  ? 149 THR A OG1 1 
ATOM   1178 C CG2 . THR A 1 152 ? 125.010 79.593  210.904 1.00 58.97  ? 149 THR A CG2 1 
ATOM   1179 N N   . MET A 1 153 ? 128.444 80.371  212.421 1.00 61.60  ? 150 MET A N   1 
ATOM   1180 C CA  . MET A 1 153 ? 129.661 80.663  211.674 1.00 56.05  ? 150 MET A CA  1 
ATOM   1181 C C   . MET A 1 153 ? 130.841 79.787  212.056 1.00 59.33  ? 150 MET A C   1 
ATOM   1182 O O   . MET A 1 153 ? 131.803 79.722  211.287 1.00 60.12  ? 150 MET A O   1 
ATOM   1183 C CB  . MET A 1 153 ? 130.055 82.118  211.868 1.00 57.97  ? 150 MET A CB  1 
ATOM   1184 C CG  . MET A 1 153 ? 128.936 83.052  211.527 1.00 64.18  ? 150 MET A CG  1 
ATOM   1185 S SD  . MET A 1 153 ? 128.451 82.915  209.814 1.00 67.23  ? 150 MET A SD  1 
ATOM   1186 C CE  . MET A 1 153 ? 129.833 83.762  209.040 1.00 62.91  ? 150 MET A CE  1 
ATOM   1187 N N   . THR A 1 154 ? 130.835 79.179  213.249 1.00 61.65  ? 151 THR A N   1 
ATOM   1188 C CA  . THR A 1 154 ? 131.930 78.305  213.660 1.00 61.82  ? 151 THR A CA  1 
ATOM   1189 C C   . THR A 1 154 ? 131.597 76.817  213.668 1.00 61.20  ? 151 THR A C   1 
ATOM   1190 O O   . THR A 1 154 ? 132.516 76.003  213.512 1.00 61.90  ? 151 THR A O   1 
ATOM   1191 C CB  . THR A 1 154 ? 132.441 78.704  215.053 1.00 59.79  ? 151 THR A CB  1 
ATOM   1192 O OG1 . THR A 1 154 ? 131.512 78.273  216.061 1.00 61.59  ? 151 THR A OG1 1 
ATOM   1193 C CG2 . THR A 1 154 ? 132.664 80.219  215.128 1.00 56.62  ? 151 THR A CG2 1 
ATOM   1194 N N   . LYS A 1 155 ? 130.317 76.442  213.797 1.00 58.63  ? 152 LYS A N   1 
ATOM   1195 C CA  . LYS A 1 155 ? 129.916 75.041  213.862 1.00 57.06  ? 152 LYS A CA  1 
ATOM   1196 C C   . LYS A 1 155 ? 129.186 74.542  212.613 1.00 63.13  ? 152 LYS A C   1 
ATOM   1197 O O   . LYS A 1 155 ? 128.941 73.334  212.514 1.00 61.21  ? 152 LYS A O   1 
ATOM   1198 C CB  . LYS A 1 155 ? 129.014 74.796  215.088 1.00 55.18  ? 152 LYS A CB  1 
ATOM   1199 C CG  . LYS A 1 155 ? 129.518 75.388  216.427 1.00 62.11  ? 152 LYS A CG  1 
ATOM   1200 C CD  . LYS A 1 155 ? 128.735 74.852  217.643 1.00 58.74  ? 152 LYS A CD  1 
ATOM   1201 C CE  . LYS A 1 155 ? 129.321 75.339  218.954 1.00 60.10  ? 152 LYS A CE  1 
ATOM   1202 N NZ  . LYS A 1 155 ? 130.780 75.642  218.874 1.00 56.19  ? 152 LYS A NZ  1 
ATOM   1203 N N   . PHE A 1 156 ? 128.889 75.415  211.633 1.00 64.06  ? 153 PHE A N   1 
ATOM   1204 C CA  . PHE A 1 156 ? 128.168 75.026  210.421 1.00 54.56  ? 153 PHE A CA  1 
ATOM   1205 C C   . PHE A 1 156 ? 128.705 75.714  209.177 1.00 59.09  ? 153 PHE A C   1 
ATOM   1206 O O   . PHE A 1 156 ? 129.145 75.040  208.236 1.00 62.91  ? 153 PHE A O   1 
ATOM   1207 C CB  . PHE A 1 156 ? 126.677 75.331  210.553 1.00 51.67  ? 153 PHE A CB  1 
ATOM   1208 C CG  . PHE A 1 156 ? 125.921 75.262  209.258 1.00 51.77  ? 153 PHE A CG  1 
ATOM   1209 C CD1 . PHE A 1 156 ? 125.844 74.086  208.545 1.00 49.13  ? 153 PHE A CD1 1 
ATOM   1210 C CD2 . PHE A 1 156 ? 125.263 76.382  208.763 1.00 57.80  ? 153 PHE A CD2 1 
ATOM   1211 C CE1 . PHE A 1 156 ? 125.143 74.033  207.348 1.00 50.20  ? 153 PHE A CE1 1 
ATOM   1212 C CE2 . PHE A 1 156 ? 124.556 76.333  207.569 1.00 52.21  ? 153 PHE A CE2 1 
ATOM   1213 C CZ  . PHE A 1 156 ? 124.500 75.155  206.865 1.00 50.10  ? 153 PHE A CZ  1 
ATOM   1214 N N   . MET A 1 157 ? 128.679 77.042  209.141 1.00 59.21  ? 154 MET A N   1 
ATOM   1215 C CA  . MET A 1 157 ? 129.128 77.729  207.937 1.00 59.44  ? 154 MET A CA  1 
ATOM   1216 C C   . MET A 1 157 ? 130.636 77.845  207.950 1.00 63.99  ? 154 MET A C   1 
ATOM   1217 O O   . MET A 1 157 ? 131.229 78.290  208.934 1.00 67.60  ? 154 MET A O   1 
ATOM   1218 C CB  . MET A 1 157 ? 128.503 79.109  207.803 1.00 54.74  ? 154 MET A CB  1 
ATOM   1219 C CG  . MET A 1 157 ? 127.229 79.064  207.018 1.00 54.51  ? 154 MET A CG  1 
ATOM   1220 S SD  . MET A 1 157 ? 126.531 80.692  206.876 1.00 56.95  ? 154 MET A SD  1 
ATOM   1221 C CE  . MET A 1 157 ? 124.967 80.317  206.103 1.00 53.90  ? 154 MET A CE  1 
ATOM   1222 N N   . GLN A 1 158 ? 131.247 77.451  206.852 1.00 67.03  ? 155 GLN A N   1 
ATOM   1223 C CA  . GLN A 1 158 ? 132.678 77.586  206.640 1.00 65.68  ? 155 GLN A CA  1 
ATOM   1224 C C   . GLN A 1 158 ? 132.831 78.597  205.515 1.00 66.57  ? 155 GLN A C   1 
ATOM   1225 O O   . GLN A 1 158 ? 132.554 78.291  204.351 1.00 72.05  ? 155 GLN A O   1 
ATOM   1226 C CB  . GLN A 1 158 ? 133.291 76.230  206.322 1.00 66.92  ? 155 GLN A CB  1 
ATOM   1227 C CG  . GLN A 1 158 ? 132.659 75.098  207.134 1.00 70.41  ? 155 GLN A CG  1 
ATOM   1228 C CD  . GLN A 1 158 ? 133.068 73.708  206.661 1.00 79.19  ? 155 GLN A CD  1 
ATOM   1229 O OE1 . GLN A 1 158 ? 132.435 73.131  205.769 1.00 71.89  ? 155 GLN A OE1 1 
ATOM   1230 N NE2 . GLN A 1 158 ? 134.139 73.165  207.257 1.00 76.25  ? 155 GLN A NE2 1 
ATOM   1231 N N   . VAL A 1 159 ? 133.215 79.818  205.870 1.00 67.31  ? 156 VAL A N   1 
ATOM   1232 C CA  . VAL A 1 159 ? 133.311 80.906  204.905 1.00 68.51  ? 156 VAL A CA  1 
ATOM   1233 C C   . VAL A 1 159 ? 134.747 80.975  204.400 1.00 71.16  ? 156 VAL A C   1 
ATOM   1234 O O   . VAL A 1 159 ? 135.672 81.270  205.156 1.00 70.20  ? 156 VAL A O   1 
ATOM   1235 C CB  . VAL A 1 159 ? 132.861 82.239  205.512 1.00 65.94  ? 156 VAL A CB  1 
ATOM   1236 C CG1 . VAL A 1 159 ? 132.772 83.302  204.441 1.00 64.59  ? 156 VAL A CG1 1 
ATOM   1237 C CG2 . VAL A 1 159 ? 131.515 82.073  206.197 1.00 65.99  ? 156 VAL A CG2 1 
ATOM   1238 N N   . ARG A 1 160 ? 134.926 80.697  203.111 1.00 78.92  ? 157 ARG A N   1 
ATOM   1239 C CA  . ARG A 1 160 ? 136.149 80.790  202.335 1.00 77.81  ? 157 ARG A CA  1 
ATOM   1240 C C   . ARG A 1 160 ? 136.304 82.219  201.812 1.00 77.62  ? 157 ARG A C   1 
ATOM   1241 O O   . ARG A 1 160 ? 135.323 82.823  201.345 1.00 70.73  ? 157 ARG A O   1 
ATOM   1242 C CB  . ARG A 1 160 ? 136.107 79.813  201.150 1.00 80.65  ? 157 ARG A CB  1 
ATOM   1243 C CG  . ARG A 1 160 ? 136.058 78.325  201.512 1.00 79.94  ? 157 ARG A CG  1 
ATOM   1244 C CD  . ARG A 1 160 ? 137.308 77.847  202.275 1.00 90.65  ? 157 ARG A CD  1 
ATOM   1245 N NE  . ARG A 1 160 ? 138.577 78.122  201.596 1.00 107.16 ? 157 ARG A NE  1 
ATOM   1246 C CZ  . ARG A 1 160 ? 139.118 77.369  200.640 1.00 115.51 ? 157 ARG A CZ  1 
ATOM   1247 N NH1 . ARG A 1 160 ? 138.495 76.303  200.158 1.00 114.29 ? 157 ARG A NH1 1 
ATOM   1248 N NH2 . ARG A 1 160 ? 140.318 77.693  200.154 1.00 109.35 ? 157 ARG A NH2 1 
ATOM   1249 N N   . PRO A 1 161 ? 137.514 82.777  201.864 1.00 78.77  ? 158 PRO A N   1 
ATOM   1250 C CA  . PRO A 1 161 ? 137.733 84.094  201.254 1.00 71.14  ? 158 PRO A CA  1 
ATOM   1251 C C   . PRO A 1 161 ? 137.348 84.028  199.789 1.00 66.34  ? 158 PRO A C   1 
ATOM   1252 O O   . PRO A 1 161 ? 137.804 83.157  199.051 1.00 65.34  ? 158 PRO A O   1 
ATOM   1253 C CB  . PRO A 1 161 ? 139.231 84.336  201.439 1.00 72.98  ? 158 PRO A CB  1 
ATOM   1254 C CG  . PRO A 1 161 ? 139.643 83.389  202.537 1.00 77.34  ? 158 PRO A CG  1 
ATOM   1255 C CD  . PRO A 1 161 ? 138.747 82.201  202.427 1.00 72.81  ? 158 PRO A CD  1 
ATOM   1256 N N   . GLY A 1 162 ? 136.487 84.945  199.369 1.00 66.49  ? 159 GLY A N   1 
ATOM   1257 C CA  . GLY A 1 162 ? 135.939 84.927  198.038 1.00 66.92  ? 159 GLY A CA  1 
ATOM   1258 C C   . GLY A 1 162 ? 134.474 84.550  197.997 1.00 69.74  ? 159 GLY A C   1 
ATOM   1259 O O   . GLY A 1 162 ? 133.773 84.939  197.053 1.00 65.91  ? 159 GLY A O   1 
ATOM   1260 N N   . ASP A 1 163 ? 134.008 83.756  198.963 1.00 70.37  ? 160 ASP A N   1 
ATOM   1261 C CA  . ASP A 1 163 ? 132.583 83.447  199.025 1.00 68.01  ? 160 ASP A CA  1 
ATOM   1262 C C   . ASP A 1 163 ? 131.769 84.744  199.058 1.00 64.94  ? 160 ASP A C   1 
ATOM   1263 O O   . ASP A 1 163 ? 132.248 85.791  199.507 1.00 65.24  ? 160 ASP A O   1 
ATOM   1264 C CB  . ASP A 1 163 ? 132.264 82.577  200.249 1.00 68.31  ? 160 ASP A CB  1 
ATOM   1265 C CG  . ASP A 1 163 ? 132.899 81.189  200.184 1.00 73.45  ? 160 ASP A CG  1 
ATOM   1266 O OD1 . ASP A 1 163 ? 133.412 80.799  199.112 1.00 74.26  ? 160 ASP A OD1 1 
ATOM   1267 O OD2 . ASP A 1 163 ? 132.857 80.469  201.208 1.00 69.61  ? 160 ASP A OD2 1 
ATOM   1268 N N   . THR A 1 164 ? 130.556 84.698  198.511 1.00 60.42  ? 161 THR A N   1 
ATOM   1269 C CA  . THR A 1 164 ? 129.606 85.802  198.629 1.00 61.08  ? 161 THR A CA  1 
ATOM   1270 C C   . THR A 1 164 ? 128.515 85.394  199.598 1.00 62.54  ? 161 THR A C   1 
ATOM   1271 O O   . THR A 1 164 ? 127.806 84.412  199.362 1.00 63.28  ? 161 THR A O   1 
ATOM   1272 C CB  . THR A 1 164 ? 128.986 86.195  197.289 1.00 66.61  ? 161 THR A CB  1 
ATOM   1273 O OG1 . THR A 1 164 ? 129.921 86.969  196.529 1.00 72.76  ? 161 THR A OG1 1 
ATOM   1274 C CG2 . THR A 1 164 ? 127.727 87.024  197.525 1.00 65.25  ? 161 THR A CG2 1 
ATOM   1275 N N   . VAL A 1 165 ? 128.374 86.152  200.675 1.00 64.19  ? 162 VAL A N   1 
ATOM   1276 C CA  . VAL A 1 165 ? 127.457 85.824  201.754 1.00 63.84  ? 162 VAL A CA  1 
ATOM   1277 C C   . VAL A 1 165 ? 126.293 86.803  201.732 1.00 64.13  ? 162 VAL A C   1 
ATOM   1278 O O   . VAL A 1 165 ? 126.497 88.023  201.727 1.00 66.48  ? 162 VAL A O   1 
ATOM   1279 C CB  . VAL A 1 165 ? 128.172 85.845  203.115 1.00 60.52  ? 162 VAL A CB  1 
ATOM   1280 C CG1 . VAL A 1 165 ? 127.169 85.616  204.229 1.00 48.13  ? 162 VAL A CG1 1 
ATOM   1281 C CG2 . VAL A 1 165 ? 129.300 84.805  203.129 1.00 55.43  ? 162 VAL A CG2 1 
ATOM   1282 N N   . VAL A 1 166 ? 125.075 86.271  201.723 1.00 62.48  ? 163 VAL A N   1 
ATOM   1283 C CA  . VAL A 1 166 ? 123.858 87.072  201.781 1.00 58.69  ? 163 VAL A CA  1 
ATOM   1284 C C   . VAL A 1 166 ? 123.225 86.864  203.150 1.00 60.93  ? 163 VAL A C   1 
ATOM   1285 O O   . VAL A 1 166 ? 123.066 85.720  203.598 1.00 58.83  ? 163 VAL A O   1 
ATOM   1286 C CB  . VAL A 1 166 ? 122.872 86.703  200.663 1.00 58.33  ? 163 VAL A CB  1 
ATOM   1287 C CG1 . VAL A 1 166 ? 121.609 87.523  200.798 1.00 51.57  ? 163 VAL A CG1 1 
ATOM   1288 C CG2 . VAL A 1 166 ? 123.520 86.898  199.283 1.00 62.92  ? 163 VAL A CG2 1 
ATOM   1289 N N   . VAL A 1 167 ? 122.926 87.969  203.834 1.00 61.11  ? 164 VAL A N   1 
ATOM   1290 C CA  . VAL A 1 167 ? 122.304 87.975  205.157 1.00 55.53  ? 164 VAL A CA  1 
ATOM   1291 C C   . VAL A 1 167 ? 120.992 88.739  205.068 1.00 59.02  ? 164 VAL A C   1 
ATOM   1292 O O   . VAL A 1 167 ? 120.970 89.895  204.629 1.00 60.60  ? 164 VAL A O   1 
ATOM   1293 C CB  . VAL A 1 167 ? 123.220 88.598  206.215 1.00 50.33  ? 164 VAL A CB  1 
ATOM   1294 C CG1 . VAL A 1 167 ? 122.497 88.665  207.505 1.00 59.77  ? 164 VAL A CG1 1 
ATOM   1295 C CG2 . VAL A 1 167 ? 124.465 87.770  206.370 1.00 49.52  ? 164 VAL A CG2 1 
ATOM   1296 N N   . SER A 1 168 ? 119.899 88.091  205.444 1.00 58.19  ? 165 SER A N   1 
ATOM   1297 C CA  . SER A 1 168 ? 118.597 88.735  205.395 1.00 59.81  ? 165 SER A CA  1 
ATOM   1298 C C   . SER A 1 168 ? 118.195 89.219  206.782 1.00 63.70  ? 165 SER A C   1 
ATOM   1299 O O   . SER A 1 168 ? 118.542 88.609  207.798 1.00 60.06  ? 165 SER A O   1 
ATOM   1300 C CB  . SER A 1 168 ? 117.540 87.797  204.825 1.00 60.06  ? 165 SER A CB  1 
ATOM   1301 O OG  . SER A 1 168 ? 117.485 86.602  205.566 1.00 62.85  ? 165 SER A OG  1 
ATOM   1302 N N   . GLY A 1 169 ? 117.459 90.326  206.812 1.00 71.20  ? 166 GLY A N   1 
ATOM   1303 C CA  . GLY A 1 169 ? 117.247 91.005  208.072 1.00 70.34  ? 166 GLY A CA  1 
ATOM   1304 C C   . GLY A 1 169 ? 118.578 91.352  208.692 1.00 73.53  ? 166 GLY A C   1 
ATOM   1305 O O   . GLY A 1 169 ? 118.779 91.141  209.892 1.00 80.23  ? 166 GLY A O   1 
ATOM   1306 N N   . ALA A 1 170 ? 119.516 91.842  207.879 1.00 71.43  ? 167 ALA A N   1 
ATOM   1307 C CA  . ALA A 1 170 ? 120.887 92.011  208.343 1.00 69.67  ? 167 ALA A CA  1 
ATOM   1308 C C   . ALA A 1 170 ? 121.006 93.082  209.415 1.00 74.17  ? 167 ALA A C   1 
ATOM   1309 O O   . ALA A 1 170 ? 121.859 92.971  210.302 1.00 71.05  ? 167 ALA A O   1 
ATOM   1310 C CB  . ALA A 1 170 ? 121.799 92.364  207.172 1.00 64.49  ? 167 ALA A CB  1 
ATOM   1311 N N   . SER A 1 171 ? 120.170 94.118  209.345 1.00 77.00  ? 168 SER A N   1 
ATOM   1312 C CA  . SER A 1 171 ? 120.341 95.293  210.193 1.00 80.59  ? 168 SER A CA  1 
ATOM   1313 C C   . SER A 1 171 ? 120.263 94.969  211.685 1.00 82.88  ? 168 SER A C   1 
ATOM   1314 O O   . SER A 1 171 ? 120.857 95.686  212.504 1.00 84.90  ? 168 SER A O   1 
ATOM   1315 C CB  . SER A 1 171 ? 119.307 96.348  209.799 1.00 82.68  ? 168 SER A CB  1 
ATOM   1316 O OG  . SER A 1 171 ? 118.031 95.752  209.678 1.00 86.34  ? 168 SER A OG  1 
ATOM   1317 N N   . GLY A 1 172 ? 119.585 93.885  212.066 1.00 80.75  ? 169 GLY A N   1 
ATOM   1318 C CA  . GLY A 1 172 ? 119.512 93.510  213.465 1.00 79.65  ? 169 GLY A CA  1 
ATOM   1319 C C   . GLY A 1 172 ? 120.802 92.878  213.944 1.00 75.03  ? 169 GLY A C   1 
ATOM   1320 O O   . GLY A 1 172 ? 121.764 92.702  213.198 1.00 77.20  ? 169 GLY A O   1 
ATOM   1321 N N   . MET A 1 173 ? 120.808 92.489  215.215 1.00 72.74  ? 170 MET A N   1 
ATOM   1322 C CA  . MET A 1 173 ? 122.083 92.167  215.846 1.00 68.42  ? 170 MET A CA  1 
ATOM   1323 C C   . MET A 1 173 ? 122.646 90.837  215.363 1.00 65.56  ? 170 MET A C   1 
ATOM   1324 O O   . MET A 1 173 ? 123.854 90.713  215.152 1.00 67.77  ? 170 MET A O   1 
ATOM   1325 C CB  . MET A 1 173 ? 121.937 92.157  217.360 1.00 71.64  ? 170 MET A CB  1 
ATOM   1326 C CG  . MET A 1 173 ? 123.151 92.729  218.070 1.00 77.95  ? 170 MET A CG  1 
ATOM   1327 S SD  . MET A 1 173 ? 123.460 92.053  219.702 1.00 66.50  ? 170 MET A SD  1 
ATOM   1328 C CE  . MET A 1 173 ? 123.910 90.415  219.217 1.00 63.03  ? 170 MET A CE  1 
ATOM   1329 N N   . ILE A 1 174 ? 121.802 89.829  215.191 1.00 68.10  ? 171 ILE A N   1 
ATOM   1330 C CA  . ILE A 1 174 ? 122.291 88.542  214.710 1.00 64.97  ? 171 ILE A CA  1 
ATOM   1331 C C   . ILE A 1 174 ? 122.818 88.657  213.285 1.00 64.95  ? 171 ILE A C   1 
ATOM   1332 O O   . ILE A 1 174 ? 123.850 88.072  212.941 1.00 60.54  ? 171 ILE A O   1 
ATOM   1333 C CB  . ILE A 1 174 ? 121.175 87.497  214.836 1.00 63.37  ? 171 ILE A CB  1 
ATOM   1334 C CG1 . ILE A 1 174 ? 120.773 87.390  216.312 1.00 58.24  ? 171 ILE A CG1 1 
ATOM   1335 C CG2 . ILE A 1 174 ? 121.620 86.177  214.247 1.00 58.31  ? 171 ILE A CG2 1 
ATOM   1336 C CD1 . ILE A 1 174 ? 119.806 86.294  216.625 1.00 64.41  ? 171 ILE A CD1 1 
ATOM   1337 N N   . GLY A 1 175 ? 122.108 89.395  212.428 1.00 74.31  ? 172 GLY A N   1 
ATOM   1338 C CA  . GLY A 1 175 ? 122.538 89.541  211.043 1.00 68.09  ? 172 GLY A CA  1 
ATOM   1339 C C   . GLY A 1 175 ? 123.793 90.380  210.883 1.00 66.67  ? 172 GLY A C   1 
ATOM   1340 O O   . GLY A 1 175 ? 124.668 90.051  210.074 1.00 64.32  ? 172 GLY A O   1 
ATOM   1341 N N   . THR A 1 176 ? 123.890 91.488  211.630 1.00 66.72  ? 173 THR A N   1 
ATOM   1342 C CA  . THR A 1 176 ? 125.107 92.294  211.596 1.00 66.52  ? 173 THR A CA  1 
ATOM   1343 C C   . THR A 1 176 ? 126.295 91.519  212.153 1.00 67.87  ? 173 THR A C   1 
ATOM   1344 O O   . THR A 1 176 ? 127.385 91.552  211.575 1.00 69.19  ? 173 THR A O   1 
ATOM   1345 C CB  . THR A 1 176 ? 124.922 93.584  212.386 1.00 66.47  ? 173 THR A CB  1 
ATOM   1346 O OG1 . THR A 1 176 ? 124.362 93.275  213.659 1.00 73.95  ? 173 THR A OG1 1 
ATOM   1347 C CG2 . THR A 1 176 ? 123.985 94.519  211.682 1.00 70.69  ? 173 THR A CG2 1 
ATOM   1348 N N   . LEU A 1 177 ? 126.099 90.794  213.258 1.00 63.59  ? 174 LEU A N   1 
ATOM   1349 C CA  . LEU A 1 177 ? 127.172 89.962  213.798 1.00 62.94  ? 174 LEU A CA  1 
ATOM   1350 C C   . LEU A 1 177 ? 127.637 88.932  212.777 1.00 66.90  ? 174 LEU A C   1 
ATOM   1351 O O   . LEU A 1 177 ? 128.841 88.747  212.574 1.00 69.20  ? 174 LEU A O   1 
ATOM   1352 C CB  . LEU A 1 177 ? 126.715 89.268  215.073 1.00 61.76  ? 174 LEU A CB  1 
ATOM   1353 C CG  . LEU A 1 177 ? 126.779 90.066  216.368 1.00 62.44  ? 174 LEU A CG  1 
ATOM   1354 C CD1 . LEU A 1 177 ? 126.529 89.123  217.493 1.00 61.95  ? 174 LEU A CD1 1 
ATOM   1355 C CD2 . LEU A 1 177 ? 128.127 90.739  216.539 1.00 69.00  ? 174 LEU A CD2 1 
ATOM   1356 N N   . VAL A 1 178 ? 126.692 88.228  212.146 1.00 67.15  ? 175 VAL A N   1 
ATOM   1357 C CA  . VAL A 1 178 ? 127.052 87.193  211.177 1.00 66.04  ? 175 VAL A CA  1 
ATOM   1358 C C   . VAL A 1 178 ? 127.826 87.803  210.020 1.00 68.10  ? 175 VAL A C   1 
ATOM   1359 O O   . VAL A 1 178 ? 128.898 87.311  209.645 1.00 66.50  ? 175 VAL A O   1 
ATOM   1360 C CB  . VAL A 1 178 ? 125.793 86.461  210.670 1.00 67.42  ? 175 VAL A CB  1 
ATOM   1361 C CG1 . VAL A 1 178 ? 126.058 85.788  209.295 1.00 57.56  ? 175 VAL A CG1 1 
ATOM   1362 C CG2 . VAL A 1 178 ? 125.297 85.458  211.694 1.00 62.89  ? 175 VAL A CG2 1 
ATOM   1363 N N   . GLY A 1 179 ? 127.294 88.893  209.446 1.00 66.46  ? 176 GLY A N   1 
ATOM   1364 C CA  . GLY A 1 179 ? 127.918 89.485  208.271 1.00 65.39  ? 176 GLY A CA  1 
ATOM   1365 C C   . GLY A 1 179 ? 129.330 89.965  208.538 1.00 68.13  ? 176 GLY A C   1 
ATOM   1366 O O   . GLY A 1 179 ? 130.231 89.746  207.722 1.00 63.51  ? 176 GLY A O   1 
ATOM   1367 N N   . GLN A 1 180 ? 129.544 90.601  209.700 1.00 65.94  ? 177 GLN A N   1 
ATOM   1368 C CA  . GLN A 1 180 ? 130.860 91.122  210.053 1.00 61.05  ? 177 GLN A CA  1 
ATOM   1369 C C   . GLN A 1 180 ? 131.872 90.005  210.202 1.00 66.32  ? 177 GLN A C   1 
ATOM   1370 O O   . GLN A 1 180 ? 133.046 90.169  209.853 1.00 69.62  ? 177 GLN A O   1 
ATOM   1371 C CB  . GLN A 1 180 ? 130.786 91.894  211.359 1.00 66.08  ? 177 GLN A CB  1 
ATOM   1372 C CG  . GLN A 1 180 ? 130.000 93.165  211.323 1.00 72.80  ? 177 GLN A CG  1 
ATOM   1373 C CD  . GLN A 1 180 ? 129.949 93.811  212.698 1.00 76.18  ? 177 GLN A CD  1 
ATOM   1374 O OE1 . GLN A 1 180 ? 130.960 94.305  213.197 1.00 75.28  ? 177 GLN A OE1 1 
ATOM   1375 N NE2 . GLN A 1 180 ? 128.769 93.797  213.322 1.00 74.08  ? 177 GLN A NE2 1 
ATOM   1376 N N   . MET A 1 181 ? 131.446 88.868  210.753 1.00 67.63  ? 178 MET A N   1 
ATOM   1377 C CA  . MET A 1 181 ? 132.345 87.727  210.826 1.00 65.95  ? 178 MET A CA  1 
ATOM   1378 C C   . MET A 1 181 ? 132.653 87.210  209.440 1.00 63.89  ? 178 MET A C   1 
ATOM   1379 O O   . MET A 1 181 ? 133.762 86.730  209.191 1.00 63.80  ? 178 MET A O   1 
ATOM   1380 C CB  . MET A 1 181 ? 131.740 86.623  211.695 1.00 64.88  ? 178 MET A CB  1 
ATOM   1381 C CG  . MET A 1 181 ? 131.391 87.064  213.120 1.00 66.43  ? 178 MET A CG  1 
ATOM   1382 S SD  . MET A 1 181 ? 130.607 85.785  214.141 1.00 62.57  ? 178 MET A SD  1 
ATOM   1383 C CE  . MET A 1 181 ? 132.032 84.762  214.516 1.00 63.31  ? 178 MET A CE  1 
ATOM   1384 N N   . ALA A 1 182 ? 131.689 87.336  208.528 1.00 67.30  ? 179 ALA A N   1 
ATOM   1385 C CA  . ALA A 1 182 ? 131.898 86.940  207.141 1.00 67.37  ? 179 ALA A CA  1 
ATOM   1386 C C   . ALA A 1 182 ? 132.859 87.884  206.442 1.00 73.04  ? 179 ALA A C   1 
ATOM   1387 O O   . ALA A 1 182 ? 133.702 87.448  205.649 1.00 75.50  ? 179 ALA A O   1 
ATOM   1388 C CB  . ALA A 1 182 ? 130.564 86.900  206.401 1.00 65.90  ? 179 ALA A CB  1 
ATOM   1389 N N   . LYS A 1 183 ? 132.720 89.187  206.686 1.00 73.90  ? 180 LYS A N   1 
ATOM   1390 C CA  . LYS A 1 183 ? 133.718 90.120  206.183 1.00 71.99  ? 180 LYS A CA  1 
ATOM   1391 C C   . LYS A 1 183 ? 135.098 89.769  206.716 1.00 69.39  ? 180 LYS A C   1 
ATOM   1392 O O   . LYS A 1 183 ? 136.103 89.883  206.006 1.00 74.74  ? 180 LYS A O   1 
ATOM   1393 C CB  . LYS A 1 183 ? 133.337 91.551  206.549 1.00 66.85  ? 180 LYS A CB  1 
ATOM   1394 C CG  . LYS A 1 183 ? 134.297 92.582  205.974 1.00 80.24  ? 180 LYS A CG  1 
ATOM   1395 C CD  . LYS A 1 183 ? 134.329 92.530  204.442 1.00 71.90  ? 180 LYS A CD  1 
ATOM   1396 C CE  . LYS A 1 183 ? 132.991 92.879  203.845 1.00 67.31  ? 180 LYS A CE  1 
ATOM   1397 N NZ  . LYS A 1 183 ? 132.951 92.439  202.436 1.00 72.23  ? 180 LYS A NZ  1 
ATOM   1398 N N   . ARG A 1 184 ? 135.164 89.319  207.960 1.00 64.00  ? 181 ARG A N   1 
ATOM   1399 C CA  . ARG A 1 184 ? 136.458 89.046  208.553 1.00 68.78  ? 181 ARG A CA  1 
ATOM   1400 C C   . ARG A 1 184 ? 137.106 87.786  207.983 1.00 67.28  ? 181 ARG A C   1 
ATOM   1401 O O   . ARG A 1 184 ? 138.337 87.704  207.919 1.00 66.12  ? 181 ARG A O   1 
ATOM   1402 C CB  . ARG A 1 184 ? 136.282 88.964  210.063 1.00 65.79  ? 181 ARG A CB  1 
ATOM   1403 C CG  . ARG A 1 184 ? 136.097 90.341  210.634 1.00 61.73  ? 181 ARG A CG  1 
ATOM   1404 C CD  . ARG A 1 184 ? 135.699 90.283  212.056 1.00 71.94  ? 181 ARG A CD  1 
ATOM   1405 N NE  . ARG A 1 184 ? 136.462 89.292  212.804 1.00 74.01  ? 181 ARG A NE  1 
ATOM   1406 C CZ  . ARG A 1 184 ? 137.626 89.543  213.389 1.00 69.51  ? 181 ARG A CZ  1 
ATOM   1407 N NH1 . ARG A 1 184 ? 138.220 90.720  213.267 1.00 75.23  ? 181 ARG A NH1 1 
ATOM   1408 N NH2 . ARG A 1 184 ? 138.199 88.599  214.133 1.00 63.74  ? 181 ARG A NH2 1 
ATOM   1409 N N   . ALA A 1 185 ? 136.310 86.810  207.556 1.00 68.34  ? 182 ALA A N   1 
ATOM   1410 C CA  . ALA A 1 185 ? 136.812 85.577  206.961 1.00 73.32  ? 182 ALA A CA  1 
ATOM   1411 C C   . ALA A 1 185 ? 137.038 85.691  205.438 1.00 74.74  ? 182 ALA A C   1 
ATOM   1412 O O   . ALA A 1 185 ? 137.294 84.674  204.772 1.00 68.64  ? 182 ALA A O   1 
ATOM   1413 C CB  . ALA A 1 185 ? 135.863 84.421  207.295 1.00 67.71  ? 182 ALA A CB  1 
ATOM   1414 N N   . GLY A 1 186 ? 136.915 86.897  204.880 1.00 71.17  ? 183 GLY A N   1 
ATOM   1415 C CA  . GLY A 1 186 ? 137.223 87.131  203.484 1.00 71.25  ? 183 GLY A CA  1 
ATOM   1416 C C   . GLY A 1 186 ? 136.058 87.069  202.528 1.00 73.44  ? 183 GLY A C   1 
ATOM   1417 O O   . GLY A 1 186 ? 136.261 86.788  201.341 1.00 72.38  ? 183 GLY A O   1 
ATOM   1418 N N   . ALA A 1 187 ? 134.845 87.351  202.991 1.00 73.70  ? 184 ALA A N   1 
ATOM   1419 C CA  . ALA A 1 187 ? 133.662 87.178  202.163 1.00 68.95  ? 184 ALA A CA  1 
ATOM   1420 C C   . ALA A 1 187 ? 133.134 88.508  201.676 1.00 69.56  ? 184 ALA A C   1 
ATOM   1421 O O   . ALA A 1 187 ? 133.158 89.509  202.396 1.00 75.35  ? 184 ALA A O   1 
ATOM   1422 C CB  . ALA A 1 187 ? 132.543 86.469  202.921 1.00 68.50  ? 184 ALA A CB  1 
ATOM   1423 N N   . ARG A 1 188 ? 132.619 88.489  200.465 1.00 64.35  ? 185 ARG A N   1 
ATOM   1424 C CA  . ARG A 1 188 ? 131.727 89.540  200.029 1.00 66.33  ? 185 ARG A CA  1 
ATOM   1425 C C   . ARG A 1 188 ? 130.407 89.367  200.756 1.00 72.09  ? 185 ARG A C   1 
ATOM   1426 O O   . ARG A 1 188 ? 129.865 88.258  200.824 1.00 72.18  ? 185 ARG A O   1 
ATOM   1427 C CB  . ARG A 1 188 ? 131.511 89.458  198.526 1.00 70.86  ? 185 ARG A CB  1 
ATOM   1428 C CG  . ARG A 1 188 ? 130.368 90.306  198.015 1.00 71.62  ? 185 ARG A CG  1 
ATOM   1429 C CD  . ARG A 1 188 ? 130.284 90.215  196.497 1.00 73.46  ? 185 ARG A CD  1 
ATOM   1430 N NE  . ARG A 1 188 ? 129.468 91.284  195.941 1.00 78.55  ? 185 ARG A NE  1 
ATOM   1431 C CZ  . ARG A 1 188 ? 129.831 92.561  195.940 1.00 82.07  ? 185 ARG A CZ  1 
ATOM   1432 N NH1 . ARG A 1 188 ? 130.986 92.955  196.469 1.00 75.72  ? 185 ARG A NH1 1 
ATOM   1433 N NH2 . ARG A 1 188 ? 129.020 93.467  195.398 1.00 71.88  ? 185 ARG A NH2 1 
ATOM   1434 N N   . VAL A 1 189 ? 129.922 90.438  201.366 1.00 70.96  ? 186 VAL A N   1 
ATOM   1435 C CA  . VAL A 1 189 ? 128.715 90.383  202.176 1.00 69.52  ? 186 VAL A CA  1 
ATOM   1436 C C   . VAL A 1 189 ? 127.626 91.199  201.505 1.00 68.71  ? 186 VAL A C   1 
ATOM   1437 O O   . VAL A 1 189 ? 127.833 92.360  201.142 1.00 73.92  ? 186 VAL A O   1 
ATOM   1438 C CB  . VAL A 1 189 ? 128.959 90.875  203.606 1.00 65.91  ? 186 VAL A CB  1 
ATOM   1439 C CG1 . VAL A 1 189 ? 127.652 90.874  204.350 1.00 62.92  ? 186 VAL A CG1 1 
ATOM   1440 C CG2 . VAL A 1 189 ? 129.956 89.965  204.287 1.00 65.66  ? 186 VAL A CG2 1 
ATOM   1441 N N   . VAL A 1 190 ? 126.473 90.586  201.336 1.00 66.82  ? 187 VAL A N   1 
ATOM   1442 C CA  . VAL A 1 190 ? 125.296 91.257  200.823 1.00 66.39  ? 187 VAL A CA  1 
ATOM   1443 C C   . VAL A 1 190 ? 124.251 91.177  201.922 1.00 68.08  ? 187 VAL A C   1 
ATOM   1444 O O   . VAL A 1 190 ? 124.030 90.102  202.494 1.00 62.04  ? 187 VAL A O   1 
ATOM   1445 C CB  . VAL A 1 190 ? 124.802 90.608  199.519 1.00 62.97  ? 187 VAL A CB  1 
ATOM   1446 C CG1 . VAL A 1 190 ? 123.616 91.359  198.968 1.00 56.54  ? 187 VAL A CG1 1 
ATOM   1447 C CG2 . VAL A 1 190 ? 125.944 90.530  198.512 1.00 68.49  ? 187 VAL A CG2 1 
ATOM   1448 N N   . GLY A 1 191 ? 123.653 92.322  202.255 1.00 68.04  ? 188 GLY A N   1 
ATOM   1449 C CA  . GLY A 1 191 ? 122.636 92.391  203.282 1.00 61.69  ? 188 GLY A CA  1 
ATOM   1450 C C   . GLY A 1 191 ? 121.376 93.029  202.738 1.00 59.87  ? 188 GLY A C   1 
ATOM   1451 O O   . GLY A 1 191 ? 121.315 93.421  201.576 1.00 65.89  ? 188 GLY A O   1 
ATOM   1452 N N   . THR A 1 192 ? 120.365 93.089  203.596 1.00 60.81  ? 189 THR A N   1 
ATOM   1453 C CA  . THR A 1 192 ? 119.063 93.628  203.222 1.00 69.06  ? 189 THR A CA  1 
ATOM   1454 C C   . THR A 1 192 ? 118.516 94.516  204.327 1.00 72.35  ? 189 THR A C   1 
ATOM   1455 O O   . THR A 1 192 ? 118.531 94.128  205.499 1.00 77.19  ? 189 THR A O   1 
ATOM   1456 C CB  . THR A 1 192 ? 118.077 92.505  202.914 1.00 68.06  ? 189 THR A CB  1 
ATOM   1457 O OG1 . THR A 1 192 ? 118.084 91.565  203.999 1.00 67.62  ? 189 THR A OG1 1 
ATOM   1458 C CG2 . THR A 1 192 ? 118.428 91.821  201.597 1.00 57.61  ? 189 THR A CG2 1 
ATOM   1459 N N   . ALA A 1 193 ? 118.025 95.694  203.954 1.00 67.90  ? 190 ALA A N   1 
ATOM   1460 C CA  . ALA A 1 193 ? 117.525 96.672  204.906 1.00 72.40  ? 190 ALA A CA  1 
ATOM   1461 C C   . ALA A 1 193 ? 116.192 97.209  204.416 1.00 80.43  ? 190 ALA A C   1 
ATOM   1462 O O   . ALA A 1 193 ? 115.791 96.983  203.273 1.00 83.06  ? 190 ALA A O   1 
ATOM   1463 C CB  . ALA A 1 193 ? 118.519 97.816  205.114 1.00 73.04  ? 190 ALA A CB  1 
ATOM   1464 N N   . GLY A 1 194 ? 115.497 97.924  205.296 1.00 76.70  ? 191 GLY A N   1 
ATOM   1465 C CA  . GLY A 1 194 ? 114.162 98.392  204.979 1.00 78.73  ? 191 GLY A CA  1 
ATOM   1466 C C   . GLY A 1 194 ? 114.053 99.875  204.709 1.00 83.44  ? 191 GLY A C   1 
ATOM   1467 O O   . GLY A 1 194 ? 113.024 100.342 204.210 1.00 83.72  ? 191 GLY A O   1 
ATOM   1468 N N   . SER A 1 195 ? 115.113 100.616 205.033 1.00 87.05  ? 192 SER A N   1 
ATOM   1469 C CA  . SER A 1 195 ? 115.155 102.065 204.900 1.00 85.01  ? 192 SER A CA  1 
ATOM   1470 C C   . SER A 1 195 ? 116.566 102.499 204.526 1.00 88.13  ? 192 SER A C   1 
ATOM   1471 O O   . SER A 1 195 ? 117.530 101.737 204.645 1.00 86.19  ? 192 SER A O   1 
ATOM   1472 C CB  . SER A 1 195 ? 114.759 102.751 206.203 1.00 88.10  ? 192 SER A CB  1 
ATOM   1473 O OG  . SER A 1 195 ? 115.827 102.633 207.128 1.00 88.53  ? 192 SER A OG  1 
ATOM   1474 N N   . ALA A 1 196 ? 116.679 103.754 204.085 1.00 87.03  ? 193 ALA A N   1 
ATOM   1475 C CA  . ALA A 1 196 ? 117.997 104.326 203.829 1.00 86.61  ? 193 ALA A CA  1 
ATOM   1476 C C   . ALA A 1 196 ? 118.824 104.435 205.101 1.00 90.18  ? 193 ALA A C   1 
ATOM   1477 O O   . ALA A 1 196 ? 120.055 104.300 205.056 1.00 82.16  ? 193 ALA A O   1 
ATOM   1478 C CB  . ALA A 1 196 ? 117.849 105.700 203.182 1.00 87.55  ? 193 ALA A CB  1 
ATOM   1479 N N   . GLY A 1 197 ? 118.165 104.710 206.234 1.00 98.51  ? 194 GLY A N   1 
ATOM   1480 C CA  . GLY A 1 197 ? 118.879 104.830 207.495 1.00 92.53  ? 194 GLY A CA  1 
ATOM   1481 C C   . GLY A 1 197 ? 119.591 103.551 207.883 1.00 94.22  ? 194 GLY A C   1 
ATOM   1482 O O   . GLY A 1 197 ? 120.802 103.549 208.129 1.00 91.95  ? 194 GLY A O   1 
ATOM   1483 N N   . LYS A 1 198 ? 118.878 102.438 207.830 1.00 93.86  ? 195 LYS A N   1 
ATOM   1484 C CA  . LYS A 1 198 ? 119.496 101.160 208.119 1.00 93.14  ? 195 LYS A CA  1 
ATOM   1485 C C   . LYS A 1 198 ? 120.475 100.782 207.029 1.00 93.86  ? 195 LYS A C   1 
ATOM   1486 O O   . LYS A 1 198 ? 121.490 100.147 207.290 1.00 90.99  ? 195 LYS A O   1 
ATOM   1487 C CB  . LYS A 1 198 ? 118.423 100.094 208.230 1.00 90.03  ? 195 LYS A CB  1 
ATOM   1488 C CG  . LYS A 1 198 ? 117.791 99.976  209.603 1.00 98.61  ? 195 LYS A CG  1 
ATOM   1489 C CD  . LYS A 1 198 ? 116.714 101.026 209.806 1.00 109.12 ? 195 LYS A CD  1 
ATOM   1490 C CE  . LYS A 1 198 ? 115.334 100.490 209.468 1.00 103.67 ? 195 LYS A CE  1 
ATOM   1491 N NZ  . LYS A 1 198 ? 114.522 100.233 210.689 1.00 101.68 ? 195 LYS A NZ  1 
ATOM   1492 N N   . ALA A 1 199 ? 120.179 101.171 205.802 1.00 93.61  ? 196 ALA A N   1 
ATOM   1493 C CA  . ALA A 1 199 ? 121.032 100.799 204.675 1.00 89.38  ? 196 ALA A CA  1 
ATOM   1494 C C   . ALA A 1 199 ? 122.429 101.406 204.791 1.00 93.95  ? 196 ALA A C   1 
ATOM   1495 O O   . ALA A 1 199 ? 123.428 100.733 204.505 1.00 92.98  ? 196 ALA A O   1 
ATOM   1496 C CB  . ALA A 1 199 ? 120.371 101.222 203.367 1.00 78.76  ? 196 ALA A CB  1 
ATOM   1497 N N   . ARG A 1 200 ? 122.525 102.688 205.169 1.00 95.62  ? 197 ARG A N   1 
ATOM   1498 C CA  . ARG A 1 200 ? 123.848 103.281 205.350 1.00 96.11  ? 197 ARG A CA  1 
ATOM   1499 C C   . ARG A 1 200 ? 124.515 102.776 206.631 1.00 97.47  ? 197 ARG A C   1 
ATOM   1500 O O   . ARG A 1 200 ? 125.745 102.656 206.682 1.00 98.78  ? 197 ARG A O   1 
ATOM   1501 C CB  . ARG A 1 200 ? 123.760 104.816 205.340 1.00 96.03  ? 197 ARG A CB  1 
ATOM   1502 C CG  . ARG A 1 200 ? 125.069 105.557 204.909 1.00 101.92 ? 197 ARG A CG  1 
ATOM   1503 C CD  . ARG A 1 200 ? 125.403 105.390 203.401 1.00 106.20 ? 197 ARG A CD  1 
ATOM   1504 N NE  . ARG A 1 200 ? 126.677 105.988 202.990 1.00 104.44 ? 197 ARG A NE  1 
ATOM   1505 C CZ  . ARG A 1 200 ? 127.202 105.895 201.768 1.00 108.71 ? 197 ARG A CZ  1 
ATOM   1506 N NH1 . ARG A 1 200 ? 126.588 105.235 200.794 1.00 97.68  ? 197 ARG A NH1 1 
ATOM   1507 N NH2 . ARG A 1 200 ? 128.377 106.476 201.516 1.00 102.67 ? 197 ARG A NH2 1 
ATOM   1508 N N   . TYR A 1 201 ? 123.726 102.460 207.665 1.00 95.08  ? 198 TYR A N   1 
ATOM   1509 C CA  . TYR A 1 201 ? 124.283 101.862 208.881 1.00 93.37  ? 198 TYR A CA  1 
ATOM   1510 C C   . TYR A 1 201 ? 124.956 100.525 208.600 1.00 92.09  ? 198 TYR A C   1 
ATOM   1511 O O   . TYR A 1 201 ? 126.088 100.283 209.038 1.00 88.62  ? 198 TYR A O   1 
ATOM   1512 C CB  . TYR A 1 201 ? 123.182 101.712 209.933 1.00 91.03  ? 198 TYR A CB  1 
ATOM   1513 C CG  . TYR A 1 201 ? 123.537 100.815 211.100 1.00 91.25  ? 198 TYR A CG  1 
ATOM   1514 C CD1 . TYR A 1 201 ? 124.712 100.997 211.825 1.00 92.49  ? 198 TYR A CD1 1 
ATOM   1515 C CD2 . TYR A 1 201 ? 122.655 99.822  211.520 1.00 98.62  ? 198 TYR A CD2 1 
ATOM   1516 C CE1 . TYR A 1 201 ? 125.030 100.169 212.901 1.00 89.76  ? 198 TYR A CE1 1 
ATOM   1517 C CE2 . TYR A 1 201 ? 122.949 99.004  212.599 1.00 96.04  ? 198 TYR A CE2 1 
ATOM   1518 C CZ  . TYR A 1 201 ? 124.140 99.179  213.281 1.00 93.71  ? 198 TYR A CZ  1 
ATOM   1519 O OH  . TYR A 1 201 ? 124.427 98.359  214.347 1.00 94.75  ? 198 TYR A OH  1 
ATOM   1520 N N   . LEU A 1 202 ? 124.283 99.654  207.844 1.00 96.00  ? 199 LEU A N   1 
ATOM   1521 C CA  . LEU A 1 202 ? 124.874 98.374  207.466 1.00 93.90  ? 199 LEU A CA  1 
ATOM   1522 C C   . LEU A 1 202 ? 126.085 98.572  206.572 1.00 90.09  ? 199 LEU A C   1 
ATOM   1523 O O   . LEU A 1 202 ? 127.031 97.772  206.608 1.00 87.60  ? 199 LEU A O   1 
ATOM   1524 C CB  . LEU A 1 202 ? 123.825 97.522  206.754 1.00 86.13  ? 199 LEU A CB  1 
ATOM   1525 C CG  . LEU A 1 202 ? 122.822 96.816  207.657 1.00 83.92  ? 199 LEU A CG  1 
ATOM   1526 C CD1 . LEU A 1 202 ? 121.612 96.378  206.861 1.00 82.53  ? 199 LEU A CD1 1 
ATOM   1527 C CD2 . LEU A 1 202 ? 123.512 95.620  208.247 1.00 76.12  ? 199 LEU A CD2 1 
ATOM   1528 N N   . SER A 1 203 ? 126.074 99.646  205.787 1.00 87.03  ? 200 SER A N   1 
ATOM   1529 C CA  . SER A 1 203 ? 127.215 99.985  204.951 1.00 87.13  ? 200 SER A CA  1 
ATOM   1530 C C   . SER A 1 203 ? 128.461 100.257 205.793 1.00 93.24  ? 200 SER A C   1 
ATOM   1531 O O   . SER A 1 203 ? 129.517 99.650  205.567 1.00 91.09  ? 200 SER A O   1 
ATOM   1532 C CB  . SER A 1 203 ? 126.859 101.181 204.078 1.00 93.61  ? 200 SER A CB  1 
ATOM   1533 O OG  . SER A 1 203 ? 127.626 101.187 202.888 1.00 105.71 ? 200 SER A OG  1 
ATOM   1534 N N   . GLN A 1 204 ? 128.346 101.143 206.794 1.00 93.04  ? 201 GLN A N   1 
ATOM   1535 C CA  . GLN A 1 204 ? 129.445 101.390 207.732 1.00 90.85  ? 201 GLN A CA  1 
ATOM   1536 C C   . GLN A 1 204 ? 130.043 100.098 208.260 1.00 88.21  ? 201 GLN A C   1 
ATOM   1537 O O   . GLN A 1 204 ? 131.264 99.910  208.236 1.00 87.77  ? 201 GLN A O   1 
ATOM   1538 C CB  . GLN A 1 204 ? 128.964 102.238 208.910 1.00 94.97  ? 201 GLN A CB  1 
ATOM   1539 C CG  . GLN A 1 204 ? 129.395 103.692 208.854 1.00 102.73 ? 201 GLN A CG  1 
ATOM   1540 C CD  . GLN A 1 204 ? 128.600 104.474 207.831 1.00 104.95 ? 201 GLN A CD  1 
ATOM   1541 O OE1 . GLN A 1 204 ? 127.403 104.696 208.013 1.00 104.22 ? 201 GLN A OE1 1 
ATOM   1542 N NE2 . GLN A 1 204 ? 129.255 104.881 206.738 1.00 94.59  ? 201 GLN A NE2 1 
ATOM   1543 N N   . LEU A 1 205 ? 129.194 99.193  208.743 1.00 87.98  ? 202 LEU A N   1 
ATOM   1544 C CA  . LEU A 1 205 ? 129.700 97.965  209.336 1.00 89.24  ? 202 LEU A CA  1 
ATOM   1545 C C   . LEU A 1 205 ? 130.497 97.140  208.331 1.00 91.57  ? 202 LEU A C   1 
ATOM   1546 O O   . LEU A 1 205 ? 131.315 96.306  208.739 1.00 85.35  ? 202 LEU A O   1 
ATOM   1547 C CB  . LEU A 1 205 ? 128.540 97.163  209.921 1.00 84.54  ? 202 LEU A CB  1 
ATOM   1548 C CG  . LEU A 1 205 ? 127.741 97.930  210.978 1.00 87.07  ? 202 LEU A CG  1 
ATOM   1549 C CD1 . LEU A 1 205 ? 126.313 97.433  211.056 1.00 86.84  ? 202 LEU A CD1 1 
ATOM   1550 C CD2 . LEU A 1 205 ? 128.413 97.831  212.325 1.00 79.17  ? 202 LEU A CD2 1 
ATOM   1551 N N   . GLY A 1 206 ? 130.317 97.397  207.033 1.00 83.01  ? 203 GLY A N   1 
ATOM   1552 C CA  . GLY A 1 206 ? 131.155 96.788  206.023 1.00 79.95  ? 203 GLY A CA  1 
ATOM   1553 C C   . GLY A 1 206 ? 130.424 95.938  204.997 1.00 84.01  ? 203 GLY A C   1 
ATOM   1554 O O   . GLY A 1 206 ? 131.058 95.274  204.174 1.00 78.61  ? 203 GLY A O   1 
ATOM   1555 N N   . PHE A 1 207 ? 129.091 95.950  205.037 1.00 85.15  ? 204 PHE A N   1 
ATOM   1556 C CA  . PHE A 1 207 ? 128.310 95.255  204.015 1.00 84.57  ? 204 PHE A CA  1 
ATOM   1557 C C   . PHE A 1 207 ? 128.601 95.844  202.635 1.00 78.97  ? 204 PHE A C   1 
ATOM   1558 O O   . PHE A 1 207 ? 128.320 97.022  202.384 1.00 83.69  ? 204 PHE A O   1 
ATOM   1559 C CB  . PHE A 1 207 ? 126.815 95.366  204.344 1.00 81.31  ? 204 PHE A CB  1 
ATOM   1560 C CG  . PHE A 1 207 ? 126.355 94.391  205.389 1.00 76.58  ? 204 PHE A CG  1 
ATOM   1561 C CD1 . PHE A 1 207 ? 126.813 94.472  206.692 1.00 77.38  ? 204 PHE A CD1 1 
ATOM   1562 C CD2 . PHE A 1 207 ? 125.463 93.397  205.069 1.00 71.14  ? 204 PHE A CD2 1 
ATOM   1563 C CE1 . PHE A 1 207 ? 126.387 93.563  207.645 1.00 72.37  ? 204 PHE A CE1 1 
ATOM   1564 C CE2 . PHE A 1 207 ? 125.034 92.498  206.018 1.00 65.23  ? 204 PHE A CE2 1 
ATOM   1565 C CZ  . PHE A 1 207 ? 125.494 92.575  207.299 1.00 68.24  ? 204 PHE A CZ  1 
ATOM   1566 N N   . ASP A 1 208 ? 129.137 95.021  201.730 1.00 73.14  ? 205 ASP A N   1 
ATOM   1567 C CA  . ASP A 1 208 ? 129.491 95.529  200.407 1.00 72.44  ? 205 ASP A CA  1 
ATOM   1568 C C   . ASP A 1 208 ? 128.272 95.979  199.617 1.00 71.25  ? 205 ASP A C   1 
ATOM   1569 O O   . ASP A 1 208 ? 128.384 96.877  198.776 1.00 75.24  ? 205 ASP A O   1 
ATOM   1570 C CB  . ASP A 1 208 ? 130.255 94.475  199.619 1.00 67.60  ? 205 ASP A CB  1 
ATOM   1571 C CG  . ASP A 1 208 ? 131.548 94.095  200.278 1.00 72.32  ? 205 ASP A CG  1 
ATOM   1572 O OD1 . ASP A 1 208 ? 132.353 95.006  200.567 1.00 77.23  ? 205 ASP A OD1 1 
ATOM   1573 O OD2 . ASP A 1 208 ? 131.763 92.888  200.512 1.00 74.55  ? 205 ASP A OD2 1 
ATOM   1574 N N   . ALA A 1 209 ? 127.109 95.388  199.875 1.00 68.76  ? 206 ALA A N   1 
ATOM   1575 C CA  . ALA A 1 209 ? 125.901 95.750  199.153 1.00 70.91  ? 206 ALA A CA  1 
ATOM   1576 C C   . ALA A 1 209 ? 124.709 95.532  200.063 1.00 73.32  ? 206 ALA A C   1 
ATOM   1577 O O   . ALA A 1 209 ? 124.659 94.548  200.808 1.00 72.19  ? 206 ALA A O   1 
ATOM   1578 C CB  . ALA A 1 209 ? 125.718 94.937  197.867 1.00 69.73  ? 206 ALA A CB  1 
ATOM   1579 N N   . VAL A 1 210 ? 123.755 96.458  199.997 1.00 72.12  ? 207 VAL A N   1 
ATOM   1580 C CA  . VAL A 1 210 ? 122.521 96.391  200.768 1.00 69.37  ? 207 VAL A CA  1 
ATOM   1581 C C   . VAL A 1 210 ? 121.355 96.597  199.813 1.00 62.42  ? 207 VAL A C   1 
ATOM   1582 O O   . VAL A 1 210 ? 121.381 97.521  198.997 1.00 69.72  ? 207 VAL A O   1 
ATOM   1583 C CB  . VAL A 1 210 ? 122.508 97.433  201.907 1.00 65.78  ? 207 VAL A CB  1 
ATOM   1584 C CG1 . VAL A 1 210 ? 121.295 97.265  202.776 1.00 69.19  ? 207 VAL A CG1 1 
ATOM   1585 C CG2 . VAL A 1 210 ? 123.756 97.283  202.752 1.00 68.43  ? 207 VAL A CG2 1 
ATOM   1586 N N   . ILE A 1 211 ? 120.336 95.747  199.929 1.00 63.33  ? 208 ILE A N   1 
ATOM   1587 C CA  . ILE A 1 211 ? 119.165 95.739  199.054 1.00 69.43  ? 208 ILE A CA  1 
ATOM   1588 C C   . ILE A 1 211 ? 117.969 96.225  199.855 1.00 71.12  ? 208 ILE A C   1 
ATOM   1589 O O   . ILE A 1 211 ? 117.749 95.771  200.982 1.00 76.84  ? 208 ILE A O   1 
ATOM   1590 C CB  . ILE A 1 211 ? 118.877 94.338  198.475 1.00 65.93  ? 208 ILE A CB  1 
ATOM   1591 C CG1 . ILE A 1 211 ? 119.873 93.939  197.383 1.00 61.27  ? 208 ILE A CG1 1 
ATOM   1592 C CG2 . ILE A 1 211 ? 117.437 94.235  197.988 1.00 68.25  ? 208 ILE A CG2 1 
ATOM   1593 C CD1 . ILE A 1 211 ? 121.242 93.650  197.881 1.00 61.99  ? 208 ILE A CD1 1 
ATOM   1594 N N   . ASP A 1 212 ? 117.183 97.122  199.268 1.00 69.42  ? 209 ASP A N   1 
ATOM   1595 C CA  . ASP A 1 212 ? 115.985 97.639  199.920 1.00 78.33  ? 209 ASP A CA  1 
ATOM   1596 C C   . ASP A 1 212 ? 114.844 96.680  199.628 1.00 80.31  ? 209 ASP A C   1 
ATOM   1597 O O   . ASP A 1 212 ? 114.234 96.731  198.562 1.00 82.51  ? 209 ASP A O   1 
ATOM   1598 C CB  . ASP A 1 212 ? 115.662 99.053  199.454 1.00 88.64  ? 209 ASP A CB  1 
ATOM   1599 C CG  . ASP A 1 212 ? 114.598 99.722  200.319 1.00 91.33  ? 209 ASP A CG  1 
ATOM   1600 O OD1 . ASP A 1 212 ? 113.490 99.152  200.435 1.00 90.79  ? 209 ASP A OD1 1 
ATOM   1601 O OD2 . ASP A 1 212 ? 114.872 100.804 200.894 1.00 87.11  ? 209 ASP A OD2 1 
ATOM   1602 N N   . TYR A 1 213 ? 114.548 95.804  200.588 1.00 84.26  ? 210 TYR A N   1 
ATOM   1603 C CA  . TYR A 1 213 ? 113.495 94.820  200.384 1.00 84.74  ? 210 TYR A CA  1 
ATOM   1604 C C   . TYR A 1 213 ? 112.124 95.466  200.244 1.00 87.76  ? 210 TYR A C   1 
ATOM   1605 O O   . TYR A 1 213 ? 111.232 94.883  199.618 1.00 88.76  ? 210 TYR A O   1 
ATOM   1606 C CB  . TYR A 1 213 ? 113.467 93.821  201.547 1.00 87.52  ? 210 TYR A CB  1 
ATOM   1607 C CG  . TYR A 1 213 ? 113.195 94.416  202.927 1.00 84.72  ? 210 TYR A CG  1 
ATOM   1608 C CD1 . TYR A 1 213 ? 111.923 94.865  203.277 1.00 85.09  ? 210 TYR A CD1 1 
ATOM   1609 C CD2 . TYR A 1 213 ? 114.201 94.497  203.884 1.00 83.84  ? 210 TYR A CD2 1 
ATOM   1610 C CE1 . TYR A 1 213 ? 111.663 95.403  204.526 1.00 86.79  ? 210 TYR A CE1 1 
ATOM   1611 C CE2 . TYR A 1 213 ? 113.949 95.024  205.145 1.00 86.18  ? 210 TYR A CE2 1 
ATOM   1612 C CZ  . TYR A 1 213 ? 112.676 95.479  205.462 1.00 86.95  ? 210 TYR A CZ  1 
ATOM   1613 O OH  . TYR A 1 213 ? 112.414 96.011  206.714 1.00 81.32  ? 210 TYR A OH  1 
ATOM   1614 N N   . LYS A 1 214 ? 111.930 96.659  200.810 1.00 86.53  ? 211 LYS A N   1 
ATOM   1615 C CA  . LYS A 1 214 ? 110.634 97.297  200.647 1.00 88.17  ? 211 LYS A CA  1 
ATOM   1616 C C   . LYS A 1 214 ? 110.489 97.888  199.253 1.00 93.37  ? 211 LYS A C   1 
ATOM   1617 O O   . LYS A 1 214 ? 109.413 97.792  198.648 1.00 96.47  ? 211 LYS A O   1 
ATOM   1618 C CB  . LYS A 1 214 ? 110.408 98.369  201.715 1.00 87.92  ? 211 LYS A CB  1 
ATOM   1619 C CG  . LYS A 1 214 ? 108.934 98.494  202.086 1.00 91.58  ? 211 LYS A CG  1 
ATOM   1620 C CD  . LYS A 1 214 ? 108.659 99.638  203.042 1.00 97.49  ? 211 LYS A CD  1 
ATOM   1621 C CE  . LYS A 1 214 ? 107.180 100.064 202.998 1.00 90.75  ? 211 LYS A CE  1 
ATOM   1622 N NZ  . LYS A 1 214 ? 106.202 98.997  203.361 1.00 87.83  ? 211 LYS A NZ  1 
ATOM   1623 N N   . LEU A 1 215 ? 111.568 98.476  198.715 1.00 93.50  ? 212 LEU A N   1 
ATOM   1624 C CA  . LEU A 1 215 ? 111.545 98.926  197.325 1.00 92.12  ? 212 LEU A CA  1 
ATOM   1625 C C   . LEU A 1 215 ? 111.323 97.749  196.379 1.00 92.25  ? 212 LEU A C   1 
ATOM   1626 O O   . LEU A 1 215 ? 110.630 97.889  195.365 1.00 95.68  ? 212 LEU A O   1 
ATOM   1627 C CB  . LEU A 1 215 ? 112.849 99.656  196.974 1.00 91.48  ? 212 LEU A CB  1 
ATOM   1628 C CG  . LEU A 1 215 ? 113.255 100.993 197.638 1.00 97.86  ? 212 LEU A CG  1 
ATOM   1629 C CD1 . LEU A 1 215 ? 114.680 101.427 197.210 1.00 93.65  ? 212 LEU A CD1 1 
ATOM   1630 C CD2 . LEU A 1 215 ? 112.241 102.142 197.485 1.00 93.82  ? 212 LEU A CD2 1 
ATOM   1631 N N   . ALA A 1 216 ? 111.840 96.570  196.734 1.00 90.20  ? 213 ALA A N   1 
ATOM   1632 C CA  . ALA A 1 216 ? 111.701 95.368  195.917 1.00 85.96  ? 213 ALA A CA  1 
ATOM   1633 C C   . ALA A 1 216 ? 110.617 94.481  196.527 1.00 89.41  ? 213 ALA A C   1 
ATOM   1634 O O   . ALA A 1 216 ? 110.840 93.347  196.957 1.00 88.90  ? 213 ALA A O   1 
ATOM   1635 C CB  . ALA A 1 216 ? 113.037 94.638  195.820 1.00 82.19  ? 213 ALA A CB  1 
ATOM   1636 N N   . ASP A 1 217 ? 109.401 95.035  196.485 1.00 94.48  ? 214 ASP A N   1 
ATOM   1637 C CA  . ASP A 1 217 ? 108.195 94.307  196.869 1.00 97.69  ? 214 ASP A CA  1 
ATOM   1638 C C   . ASP A 1 217 ? 108.060 93.015  196.073 1.00 98.77  ? 214 ASP A C   1 
ATOM   1639 O O   . ASP A 1 217 ? 107.655 91.979  196.611 1.00 98.27  ? 214 ASP A O   1 
ATOM   1640 C CB  . ASP A 1 217 ? 106.983 95.226  196.635 1.00 98.41  ? 214 ASP A CB  1 
ATOM   1641 C CG  . ASP A 1 217 ? 105.785 94.893  197.517 1.00 104.91 ? 214 ASP A CG  1 
ATOM   1642 O OD1 . ASP A 1 217 ? 105.494 93.692  197.720 1.00 101.31 ? 214 ASP A OD1 1 
ATOM   1643 O OD2 . ASP A 1 217 ? 105.121 95.847  197.996 1.00 104.27 ? 214 ASP A OD2 1 
ATOM   1644 N N   . ASP A 1 218 ? 108.467 93.048  194.811 1.00 100.66 ? 215 ASP A N   1 
ATOM   1645 C CA  . ASP A 1 218 ? 108.394 91.920  193.894 1.00 102.23 ? 215 ASP A CA  1 
ATOM   1646 C C   . ASP A 1 218 ? 109.507 90.905  194.164 1.00 100.24 ? 215 ASP A C   1 
ATOM   1647 O O   . ASP A 1 218 ? 110.597 91.246  194.641 1.00 94.18  ? 215 ASP A O   1 
ATOM   1648 C CB  . ASP A 1 218 ? 108.485 92.464  192.458 1.00 104.06 ? 215 ASP A CB  1 
ATOM   1649 C CG  . ASP A 1 218 ? 108.247 91.407  191.374 1.00 110.38 ? 215 ASP A CG  1 
ATOM   1650 O OD1 . ASP A 1 218 ? 107.868 90.259  191.697 1.00 109.81 ? 215 ASP A OD1 1 
ATOM   1651 O OD2 . ASP A 1 218 ? 108.439 91.743  190.178 1.00 109.55 ? 215 ASP A OD2 1 
ATOM   1652 N N   . ALA A 1 219 ? 109.206 89.632  193.883 1.00 100.53 ? 216 ALA A N   1 
ATOM   1653 C CA  . ALA A 1 219 ? 110.222 88.596  194.016 1.00 94.50  ? 216 ALA A CA  1 
ATOM   1654 C C   . ALA A 1 219 ? 111.135 88.570  192.794 1.00 95.36  ? 216 ALA A C   1 
ATOM   1655 O O   . ALA A 1 219 ? 112.301 88.173  192.899 1.00 95.05  ? 216 ALA A O   1 
ATOM   1656 C CB  . ALA A 1 219 ? 109.556 87.233  194.232 1.00 88.32  ? 216 ALA A CB  1 
ATOM   1657 N N   . ASP A 1 220 ? 110.631 89.008  191.639 1.00 96.45  ? 217 ASP A N   1 
ATOM   1658 C CA  . ASP A 1 220 ? 111.482 89.176  190.465 1.00 95.34  ? 217 ASP A CA  1 
ATOM   1659 C C   . ASP A 1 220 ? 112.392 90.382  190.644 1.00 93.15  ? 217 ASP A C   1 
ATOM   1660 O O   . ASP A 1 220 ? 113.615 90.286  190.493 1.00 90.04  ? 217 ASP A O   1 
ATOM   1661 C CB  . ASP A 1 220 ? 110.631 89.331  189.202 1.00 98.07  ? 217 ASP A CB  1 
ATOM   1662 C CG  . ASP A 1 220 ? 110.442 88.023  188.448 1.00 101.17 ? 217 ASP A CG  1 
ATOM   1663 O OD1 . ASP A 1 220 ? 111.347 87.155  188.481 1.00 98.38  ? 217 ASP A OD1 1 
ATOM   1664 O OD2 . ASP A 1 220 ? 109.380 87.874  187.807 1.00 98.55  ? 217 ASP A OD2 1 
ATOM   1665 N N   . LYS A 1 221 ? 111.807 91.522  191.014 1.00 95.23  ? 218 LYS A N   1 
ATOM   1666 C CA  . LYS A 1 221 ? 112.600 92.723  191.233 1.00 94.32  ? 218 LYS A CA  1 
ATOM   1667 C C   . LYS A 1 221 ? 113.628 92.513  192.338 1.00 90.49  ? 218 LYS A C   1 
ATOM   1668 O O   . LYS A 1 221 ? 114.720 93.089  192.285 1.00 88.51  ? 218 LYS A O   1 
ATOM   1669 C CB  . LYS A 1 221 ? 111.656 93.879  191.575 1.00 93.46  ? 218 LYS A CB  1 
ATOM   1670 C CG  . LYS A 1 221 ? 110.707 94.218  190.431 1.00 103.23 ? 218 LYS A CG  1 
ATOM   1671 C CD  . LYS A 1 221 ? 110.136 95.623  190.513 1.00 105.44 ? 218 LYS A CD  1 
ATOM   1672 C CE  . LYS A 1 221 ? 109.316 95.932  189.264 1.00 102.58 ? 218 LYS A CE  1 
ATOM   1673 N NZ  . LYS A 1 221 ? 108.700 97.283  189.301 1.00 90.51  ? 218 LYS A NZ  1 
ATOM   1674 N N   . MET A 1 222 ? 113.325 91.638  193.304 1.00 92.70  ? 219 MET A N   1 
ATOM   1675 C CA  . MET A 1 222 ? 114.304 91.231  194.309 1.00 86.99  ? 219 MET A CA  1 
ATOM   1676 C C   . MET A 1 222 ? 115.373 90.329  193.703 1.00 84.83  ? 219 MET A C   1 
ATOM   1677 O O   . MET A 1 222 ? 116.520 90.331  194.169 1.00 81.41  ? 219 MET A O   1 
ATOM   1678 C CB  . MET A 1 222 ? 113.607 90.525  195.474 1.00 89.13  ? 219 MET A CB  1 
ATOM   1679 C CG  . MET A 1 222 ? 114.524 90.035  196.612 1.00 86.56  ? 219 MET A CG  1 
ATOM   1680 S SD  . MET A 1 222 ? 115.350 91.341  197.560 1.00 83.87  ? 219 MET A SD  1 
ATOM   1681 C CE  . MET A 1 222 ? 113.905 92.137  198.246 1.00 85.00  ? 219 MET A CE  1 
ATOM   1682 N N   . ARG A 1 223 ? 115.002 89.513  192.705 1.00 83.08  ? 220 ARG A N   1 
ATOM   1683 C CA  . ARG A 1 223 ? 115.980 88.650  192.049 1.00 79.46  ? 220 ARG A CA  1 
ATOM   1684 C C   . ARG A 1 223 ? 116.960 89.457  191.204 1.00 79.85  ? 220 ARG A C   1 
ATOM   1685 O O   . ARG A 1 223 ? 118.097 89.021  190.995 1.00 79.18  ? 220 ARG A O   1 
ATOM   1686 C CB  . ARG A 1 223 ? 115.275 87.615  191.163 1.00 81.16  ? 220 ARG A CB  1 
ATOM   1687 C CG  . ARG A 1 223 ? 116.133 86.393  190.770 1.00 79.36  ? 220 ARG A CG  1 
ATOM   1688 C CD  . ARG A 1 223 ? 115.505 85.535  189.645 1.00 85.57  ? 220 ARG A CD  1 
ATOM   1689 N NE  . ARG A 1 223 ? 114.049 85.647  189.582 1.00 98.56  ? 220 ARG A NE  1 
ATOM   1690 C CZ  . ARG A 1 223 ? 113.183 84.863  190.215 1.00 96.10  ? 220 ARG A CZ  1 
ATOM   1691 N NH1 . ARG A 1 223 ? 113.584 83.876  191.001 1.00 91.99  ? 220 ARG A NH1 1 
ATOM   1692 N NH2 . ARG A 1 223 ? 111.878 85.088  190.069 1.00 93.58  ? 220 ARG A NH2 1 
ATOM   1693 N N   . GLU A 1 224 ? 116.554 90.637  190.722 1.00 82.73  ? 221 GLU A N   1 
ATOM   1694 C CA  . GLU A 1 224 ? 117.466 91.454  189.924 1.00 84.57  ? 221 GLU A CA  1 
ATOM   1695 C C   . GLU A 1 224 ? 118.460 92.185  190.813 1.00 77.53  ? 221 GLU A C   1 
ATOM   1696 O O   . GLU A 1 224 ? 119.672 92.129  190.580 1.00 71.83  ? 221 GLU A O   1 
ATOM   1697 C CB  . GLU A 1 224 ? 116.687 92.456  189.068 1.00 87.34  ? 221 GLU A CB  1 
ATOM   1698 C CG  . GLU A 1 224 ? 115.789 91.813  188.034 1.00 92.62  ? 221 GLU A CG  1 
ATOM   1699 C CD  . GLU A 1 224 ? 115.259 92.796  187.016 1.00 99.52  ? 221 GLU A CD  1 
ATOM   1700 O OE1 . GLU A 1 224 ? 115.378 94.023  187.239 1.00 98.52  ? 221 GLU A OE1 1 
ATOM   1701 O OE2 . GLU A 1 224 ? 114.720 92.329  185.988 1.00 100.00 ? 221 GLU A OE2 1 
ATOM   1702 N N   . ALA A 1 225 ? 117.952 92.854  191.853 1.00 82.21  ? 222 ALA A N   1 
ATOM   1703 C CA  . ALA A 1 225 ? 118.809 93.469  192.857 1.00 77.06  ? 222 ALA A CA  1 
ATOM   1704 C C   . ALA A 1 225 ? 119.829 92.470  193.377 1.00 78.05  ? 222 ALA A C   1 
ATOM   1705 O O   . ALA A 1 225 ? 121.001 92.807  193.591 1.00 75.70  ? 222 ALA A O   1 
ATOM   1706 C CB  . ALA A 1 225 ? 117.946 93.998  194.000 1.00 69.79  ? 222 ALA A CB  1 
ATOM   1707 N N   . LEU A 1 226 ? 119.396 91.224  193.556 1.00 78.25  ? 223 LEU A N   1 
ATOM   1708 C CA  . LEU A 1 226 ? 120.284 90.165  194.005 1.00 75.59  ? 223 LEU A CA  1 
ATOM   1709 C C   . LEU A 1 226 ? 121.272 89.749  192.921 1.00 78.56  ? 223 LEU A C   1 
ATOM   1710 O O   . LEU A 1 226 ? 122.447 89.505  193.220 1.00 77.36  ? 223 LEU A O   1 
ATOM   1711 C CB  . LEU A 1 226 ? 119.448 88.983  194.474 1.00 74.47  ? 223 LEU A CB  1 
ATOM   1712 C CG  . LEU A 1 226 ? 119.103 89.101  195.958 1.00 75.84  ? 223 LEU A CG  1 
ATOM   1713 C CD1 . LEU A 1 226 ? 118.242 87.943  196.349 1.00 69.19  ? 223 LEU A CD1 1 
ATOM   1714 C CD2 . LEU A 1 226 ? 120.374 89.136  196.812 1.00 61.80  ? 223 LEU A CD2 1 
ATOM   1715 N N   . ARG A 1 227 ? 120.815 89.639  191.659 1.00 80.77  ? 224 ARG A N   1 
ATOM   1716 C CA  . ARG A 1 227 ? 121.727 89.262  190.574 1.00 77.32  ? 224 ARG A CA  1 
ATOM   1717 C C   . ARG A 1 227 ? 122.873 90.258  190.415 1.00 77.63  ? 224 ARG A C   1 
ATOM   1718 O O   . ARG A 1 227 ? 124.001 89.865  190.093 1.00 78.55  ? 224 ARG A O   1 
ATOM   1719 C CB  . ARG A 1 227 ? 120.995 89.122  189.237 1.00 80.69  ? 224 ARG A CB  1 
ATOM   1720 C CG  . ARG A 1 227 ? 120.777 87.678  188.754 1.00 82.17  ? 224 ARG A CG  1 
ATOM   1721 C CD  . ARG A 1 227 ? 120.347 87.651  187.291 1.00 75.91  ? 224 ARG A CD  1 
ATOM   1722 N NE  . ARG A 1 227 ? 119.301 88.631  187.008 1.00 87.78  ? 224 ARG A NE  1 
ATOM   1723 C CZ  . ARG A 1 227 ? 117.995 88.395  187.072 1.00 93.44  ? 224 ARG A CZ  1 
ATOM   1724 N NH1 . ARG A 1 227 ? 117.519 87.202  187.395 1.00 95.13  ? 224 ARG A NH1 1 
ATOM   1725 N NH2 . ARG A 1 227 ? 117.144 89.380  186.795 1.00 87.97  ? 224 ARG A NH2 1 
ATOM   1726 N N   . GLU A 1 228 ? 122.604 91.554  190.591 1.00 78.23  ? 225 GLU A N   1 
ATOM   1727 C CA  . GLU A 1 228 ? 123.690 92.521  190.450 1.00 83.80  ? 225 GLU A CA  1 
ATOM   1728 C C   . GLU A 1 228 ? 124.522 92.628  191.726 1.00 85.27  ? 225 GLU A C   1 
ATOM   1729 O O   . GLU A 1 228 ? 125.751 92.761  191.653 1.00 85.75  ? 225 GLU A O   1 
ATOM   1730 C CB  . GLU A 1 228 ? 123.157 93.899  190.039 1.00 83.59  ? 225 GLU A CB  1 
ATOM   1731 C CG  . GLU A 1 228 ? 124.221 94.771  189.350 1.00 84.20  ? 225 GLU A CG  1 
ATOM   1732 C CD  . GLU A 1 228 ? 124.706 94.157  188.018 1.00 90.63  ? 225 GLU A CD  1 
ATOM   1733 O OE1 . GLU A 1 228 ? 123.844 93.897  187.147 1.00 89.13  ? 225 GLU A OE1 1 
ATOM   1734 O OE2 . GLU A 1 228 ? 125.932 93.921  187.847 1.00 83.98  ? 225 GLU A OE2 1 
ATOM   1735 N N   . ALA A 1 229 ? 123.881 92.571  192.902 1.00 77.13  ? 226 ALA A N   1 
ATOM   1736 C CA  . ALA A 1 229 ? 124.632 92.707  194.149 1.00 80.97  ? 226 ALA A CA  1 
ATOM   1737 C C   . ALA A 1 229 ? 125.568 91.519  194.371 1.00 85.12  ? 226 ALA A C   1 
ATOM   1738 O O   . ALA A 1 229 ? 126.657 91.676  194.945 1.00 81.00  ? 226 ALA A O   1 
ATOM   1739 C CB  . ALA A 1 229 ? 123.679 92.875  195.328 1.00 77.45  ? 226 ALA A CB  1 
ATOM   1740 N N   . ALA A 1 230 ? 125.153 90.317  193.954 1.00 81.60  ? 227 ALA A N   1 
ATOM   1741 C CA  . ALA A 1 230 ? 125.964 89.104  194.055 1.00 80.04  ? 227 ALA A CA  1 
ATOM   1742 C C   . ALA A 1 230 ? 126.208 88.611  192.638 1.00 84.03  ? 227 ALA A C   1 
ATOM   1743 O O   . ALA A 1 230 ? 125.538 87.673  192.180 1.00 83.74  ? 227 ALA A O   1 
ATOM   1744 C CB  . ALA A 1 230 ? 125.282 88.019  194.877 1.00 83.20  ? 227 ALA A CB  1 
ATOM   1745 N N   . PRO A 1 231 ? 127.175 89.197  191.927 1.00 86.45  ? 228 PRO A N   1 
ATOM   1746 C CA  . PRO A 1 231 ? 127.329 88.879  190.503 1.00 80.07  ? 228 PRO A CA  1 
ATOM   1747 C C   . PRO A 1 231 ? 127.847 87.481  190.247 1.00 79.77  ? 228 PRO A C   1 
ATOM   1748 O O   . PRO A 1 231 ? 127.646 86.961  189.142 1.00 79.92  ? 228 PRO A O   1 
ATOM   1749 C CB  . PRO A 1 231 ? 128.321 89.941  190.024 1.00 83.47  ? 228 PRO A CB  1 
ATOM   1750 C CG  . PRO A 1 231 ? 129.166 90.191  191.231 1.00 83.30  ? 228 PRO A CG  1 
ATOM   1751 C CD  . PRO A 1 231 ? 128.229 90.108  192.408 1.00 86.04  ? 228 PRO A CD  1 
ATOM   1752 N N   . ASP A 1 232 ? 128.488 86.847  191.231 1.00 77.60  ? 229 ASP A N   1 
ATOM   1753 C CA  . ASP A 1 232 ? 129.077 85.528  191.051 1.00 79.68  ? 229 ASP A CA  1 
ATOM   1754 C C   . ASP A 1 232 ? 128.317 84.431  191.786 1.00 77.30  ? 229 ASP A C   1 
ATOM   1755 O O   . ASP A 1 232 ? 128.778 83.286  191.807 1.00 80.71  ? 229 ASP A O   1 
ATOM   1756 C CB  . ASP A 1 232 ? 130.551 85.520  191.473 1.00 78.79  ? 229 ASP A CB  1 
ATOM   1757 C CG  . ASP A 1 232 ? 131.454 86.253  190.486 1.00 87.47  ? 229 ASP A CG  1 
ATOM   1758 O OD1 . ASP A 1 232 ? 131.149 87.415  190.147 1.00 91.06  ? 229 ASP A OD1 1 
ATOM   1759 O OD2 . ASP A 1 232 ? 132.468 85.659  190.040 1.00 87.23  ? 229 ASP A OD2 1 
ATOM   1760 N N   . GLY A 1 233 ? 127.165 84.740  192.372 1.00 73.07  ? 230 GLY A N   1 
ATOM   1761 C CA  . GLY A 1 233 ? 126.354 83.724  193.006 1.00 67.02  ? 230 GLY A CA  1 
ATOM   1762 C C   . GLY A 1 233 ? 126.465 83.758  194.524 1.00 70.16  ? 230 GLY A C   1 
ATOM   1763 O O   . GLY A 1 233 ? 127.388 84.335  195.104 1.00 71.49  ? 230 GLY A O   1 
ATOM   1764 N N   . VAL A 1 234 ? 125.503 83.124  195.182 1.00 64.00  ? 231 VAL A N   1 
ATOM   1765 C CA  . VAL A 1 234 ? 125.491 83.075  196.638 1.00 58.29  ? 231 VAL A CA  1 
ATOM   1766 C C   . VAL A 1 234 ? 126.171 81.797  197.082 1.00 58.09  ? 231 VAL A C   1 
ATOM   1767 O O   . VAL A 1 234 ? 125.837 80.711  196.604 1.00 59.72  ? 231 VAL A O   1 
ATOM   1768 C CB  . VAL A 1 234 ? 124.059 83.135  197.182 1.00 60.58  ? 231 VAL A CB  1 
ATOM   1769 C CG1 . VAL A 1 234 ? 124.087 83.135  198.701 1.00 57.55  ? 231 VAL A CG1 1 
ATOM   1770 C CG2 . VAL A 1 234 ? 123.344 84.350  196.640 1.00 67.92  ? 231 VAL A CG2 1 
ATOM   1771 N N   . ASP A 1 235 ? 127.120 81.919  198.003 1.00 57.47  ? 232 ASP A N   1 
ATOM   1772 C CA  . ASP A 1 235 ? 127.759 80.752  198.592 1.00 57.20  ? 232 ASP A CA  1 
ATOM   1773 C C   . ASP A 1 235 ? 127.296 80.454  199.998 1.00 53.20  ? 232 ASP A C   1 
ATOM   1774 O O   . ASP A 1 235 ? 127.353 79.297  200.409 1.00 55.96  ? 232 ASP A O   1 
ATOM   1775 C CB  . ASP A 1 235 ? 129.282 80.895  198.597 1.00 66.10  ? 232 ASP A CB  1 
ATOM   1776 C CG  . ASP A 1 235 ? 129.899 80.593  197.244 1.00 64.70  ? 232 ASP A CG  1 
ATOM   1777 O OD1 . ASP A 1 235 ? 129.709 79.458  196.733 1.00 55.01  ? 232 ASP A OD1 1 
ATOM   1778 O OD2 . ASP A 1 235 ? 130.590 81.486  196.714 1.00 63.88  ? 232 ASP A OD2 1 
ATOM   1779 N N   . LYS A 1 236 ? 126.903 81.475  200.762 1.00 58.14  ? 233 LYS A N   1 
ATOM   1780 C CA  . LYS A 1 236 ? 126.326 81.289  202.090 1.00 56.35  ? 233 LYS A CA  1 
ATOM   1781 C C   . LYS A 1 236 ? 125.136 82.230  202.238 1.00 53.86  ? 233 LYS A C   1 
ATOM   1782 O O   . LYS A 1 236 ? 125.240 83.423  201.936 1.00 55.30  ? 233 LYS A O   1 
ATOM   1783 C CB  . LYS A 1 236 ? 127.337 81.574  203.209 1.00 51.42  ? 233 LYS A CB  1 
ATOM   1784 C CG  . LYS A 1 236 ? 128.756 81.104  202.958 1.00 57.42  ? 233 LYS A CG  1 
ATOM   1785 C CD  . LYS A 1 236 ? 129.041 79.642  203.217 1.00 56.52  ? 233 LYS A CD  1 
ATOM   1786 C CE  . LYS A 1 236 ? 130.153 79.206  202.255 1.00 58.38  ? 233 LYS A CE  1 
ATOM   1787 N NZ  . LYS A 1 236 ? 130.720 77.862  202.520 1.00 56.82  ? 233 LYS A NZ  1 
ATOM   1788 N N   . TYR A 1 237 ? 124.021 81.702  202.728 1.00 50.77  ? 234 TYR A N   1 
ATOM   1789 C CA  . TYR A 1 237 ? 122.819 82.483  202.995 1.00 51.01  ? 234 TYR A CA  1 
ATOM   1790 C C   . TYR A 1 237 ? 122.474 82.352  204.478 1.00 55.33  ? 234 TYR A C   1 
ATOM   1791 O O   . TYR A 1 237 ? 122.189 81.250  204.959 1.00 55.31  ? 234 TYR A O   1 
ATOM   1792 C CB  . TYR A 1 237 ? 121.665 81.997  202.115 1.00 46.06  ? 234 TYR A CB  1 
ATOM   1793 C CG  . TYR A 1 237 ? 120.388 82.801  202.209 1.00 50.69  ? 234 TYR A CG  1 
ATOM   1794 C CD1 . TYR A 1 237 ? 120.389 84.108  202.672 1.00 52.00  ? 234 TYR A CD1 1 
ATOM   1795 C CD2 . TYR A 1 237 ? 119.173 82.250  201.817 1.00 53.83  ? 234 TYR A CD2 1 
ATOM   1796 C CE1 . TYR A 1 237 ? 119.216 84.842  202.750 1.00 49.95  ? 234 TYR A CE1 1 
ATOM   1797 C CE2 . TYR A 1 237 ? 117.996 82.979  201.887 1.00 51.27  ? 234 TYR A CE2 1 
ATOM   1798 C CZ  . TYR A 1 237 ? 118.030 84.271  202.350 1.00 52.16  ? 234 TYR A CZ  1 
ATOM   1799 O OH  . TYR A 1 237 ? 116.870 84.994  202.424 1.00 55.41  ? 234 TYR A OH  1 
ATOM   1800 N N   . PHE A 1 238 ? 122.511 83.461  205.214 1.00 52.01  ? 235 PHE A N   1 
ATOM   1801 C CA  . PHE A 1 238 ? 121.993 83.469  206.574 1.00 48.62  ? 235 PHE A CA  1 
ATOM   1802 C C   . PHE A 1 238 ? 120.619 84.117  206.553 1.00 52.71  ? 235 PHE A C   1 
ATOM   1803 O O   . PHE A 1 238 ? 120.512 85.342  206.436 1.00 52.68  ? 235 PHE A O   1 
ATOM   1804 C CB  . PHE A 1 238 ? 122.912 84.208  207.528 1.00 49.47  ? 235 PHE A CB  1 
ATOM   1805 C CG  . PHE A 1 238 ? 122.516 84.036  208.948 1.00 54.73  ? 235 PHE A CG  1 
ATOM   1806 C CD1 . PHE A 1 238 ? 122.919 82.919  209.658 1.00 53.66  ? 235 PHE A CD1 1 
ATOM   1807 C CD2 . PHE A 1 238 ? 121.707 84.963  209.569 1.00 53.59  ? 235 PHE A CD2 1 
ATOM   1808 C CE1 . PHE A 1 238 ? 122.536 82.750  210.957 1.00 50.47  ? 235 PHE A CE1 1 
ATOM   1809 C CE2 . PHE A 1 238 ? 121.325 84.792  210.865 1.00 51.98  ? 235 PHE A CE2 1 
ATOM   1810 C CZ  . PHE A 1 238 ? 121.736 83.686  211.557 1.00 51.31  ? 235 PHE A CZ  1 
ATOM   1811 N N   . ASP A 1 239 ? 119.573 83.301  206.714 1.00 51.50  ? 236 ASP A N   1 
ATOM   1812 C CA  . ASP A 1 239 ? 118.204 83.704  206.410 1.00 50.66  ? 236 ASP A CA  1 
ATOM   1813 C C   . ASP A 1 239 ? 117.398 83.894  207.671 1.00 51.99  ? 236 ASP A C   1 
ATOM   1814 O O   . ASP A 1 239 ? 117.178 82.935  208.411 1.00 57.01  ? 236 ASP A O   1 
ATOM   1815 C CB  . ASP A 1 239 ? 117.475 82.684  205.547 1.00 52.15  ? 236 ASP A CB  1 
ATOM   1816 C CG  . ASP A 1 239 ? 116.087 83.173  205.131 1.00 55.27  ? 236 ASP A CG  1 
ATOM   1817 O OD1 . ASP A 1 239 ? 115.856 84.401  205.101 1.00 56.57  ? 236 ASP A OD1 1 
ATOM   1818 O OD2 . ASP A 1 239 ? 115.208 82.332  204.857 1.00 57.34  ? 236 ASP A OD2 1 
ATOM   1819 N N   . SER A 1 240 ? 116.916 85.113  207.880 1.00 54.42  ? 237 SER A N   1 
ATOM   1820 C CA  . SER A 1 240 ? 115.965 85.397  208.937 1.00 54.64  ? 237 SER A CA  1 
ATOM   1821 C C   . SER A 1 240 ? 114.590 85.769  208.420 1.00 55.13  ? 237 SER A C   1 
ATOM   1822 O O   . SER A 1 240 ? 113.638 85.773  209.199 1.00 56.34  ? 237 SER A O   1 
ATOM   1823 C CB  . SER A 1 240 ? 116.476 86.543  209.810 1.00 57.47  ? 237 SER A CB  1 
ATOM   1824 O OG  . SER A 1 240 ? 117.556 86.103  210.599 1.00 61.70  ? 237 SER A OG  1 
ATOM   1825 N N   . ILE A 1 241 ? 114.445 86.028  207.131 1.00 62.41  ? 238 ILE A N   1 
ATOM   1826 C CA  . ILE A 1 241 ? 113.243 86.638  206.589 1.00 62.47  ? 238 ILE A CA  1 
ATOM   1827 C C   . ILE A 1 241 ? 112.380 85.629  205.842 1.00 57.45  ? 238 ILE A C   1 
ATOM   1828 O O   . ILE A 1 241 ? 111.180 85.522  206.093 1.00 59.84  ? 238 ILE A O   1 
ATOM   1829 C CB  . ILE A 1 241 ? 113.601 87.829  205.683 1.00 59.24  ? 238 ILE A CB  1 
ATOM   1830 C CG1 . ILE A 1 241 ? 114.285 88.923  206.503 1.00 64.88  ? 238 ILE A CG1 1 
ATOM   1831 C CG2 . ILE A 1 241 ? 112.353 88.332  205.053 1.00 62.46  ? 238 ILE A CG2 1 
ATOM   1832 C CD1 . ILE A 1 241 ? 113.666 89.145  207.856 1.00 67.97  ? 238 ILE A CD1 1 
ATOM   1833 N N   . GLY A 1 242 ? 112.975 84.869  204.935 1.00 53.84  ? 239 GLY A N   1 
ATOM   1834 C CA  . GLY A 1 242 ? 112.185 83.963  204.126 1.00 58.49  ? 239 GLY A CA  1 
ATOM   1835 C C   . GLY A 1 242 ? 111.425 84.705  203.036 1.00 62.90  ? 239 GLY A C   1 
ATOM   1836 O O   . GLY A 1 242 ? 111.864 85.736  202.528 1.00 64.98  ? 239 GLY A O   1 
ATOM   1837 N N   . GLY A 1 243 ? 110.242 84.191  202.705 1.00 66.78  ? 240 GLY A N   1 
ATOM   1838 C CA  . GLY A 1 243 ? 109.407 84.890  201.736 1.00 66.70  ? 240 GLY A CA  1 
ATOM   1839 C C   . GLY A 1 243 ? 110.092 85.029  200.392 1.00 69.54  ? 240 GLY A C   1 
ATOM   1840 O O   . GLY A 1 243 ? 110.765 84.110  199.908 1.00 66.34  ? 240 GLY A O   1 
ATOM   1841 N N   . SER A 1 244 ? 109.890 86.186  199.757 1.00 70.10  ? 241 SER A N   1 
ATOM   1842 C CA  . SER A 1 244 ? 110.337 86.346  198.382 1.00 69.76  ? 241 SER A CA  1 
ATOM   1843 C C   . SER A 1 244 ? 111.843 86.547  198.253 1.00 67.28  ? 241 SER A C   1 
ATOM   1844 O O   . SER A 1 244 ? 112.385 86.328  197.163 1.00 69.81  ? 241 SER A O   1 
ATOM   1845 C CB  . SER A 1 244 ? 109.607 87.521  197.730 1.00 76.19  ? 241 SER A CB  1 
ATOM   1846 O OG  . SER A 1 244 ? 110.355 88.719  197.843 1.00 80.15  ? 241 SER A OG  1 
ATOM   1847 N N   . VAL A 1 245 ? 112.537 86.941  199.322 1.00 64.57  ? 242 VAL A N   1 
ATOM   1848 C CA  . VAL A 1 245 ? 113.984 87.086  199.203 1.00 63.79  ? 242 VAL A CA  1 
ATOM   1849 C C   . VAL A 1 245 ? 114.660 85.729  199.230 1.00 62.31  ? 242 VAL A C   1 
ATOM   1850 O O   . VAL A 1 245 ? 115.624 85.496  198.498 1.00 65.62  ? 242 VAL A O   1 
ATOM   1851 C CB  . VAL A 1 245 ? 114.567 88.031  200.269 1.00 63.19  ? 242 VAL A CB  1 
ATOM   1852 C CG1 . VAL A 1 245 ? 114.061 87.687  201.620 1.00 63.55  ? 242 VAL A CG1 1 
ATOM   1853 C CG2 . VAL A 1 245 ? 116.083 87.959  200.251 1.00 58.91  ? 242 VAL A CG2 1 
ATOM   1854 N N   . THR A 1 246 ? 114.198 84.810  200.073 1.00 59.82  ? 243 THR A N   1 
ATOM   1855 C CA  . THR A 1 246 ? 114.780 83.474  200.007 1.00 63.72  ? 243 THR A CA  1 
ATOM   1856 C C   . THR A 1 246 ? 114.429 82.791  198.686 1.00 64.62  ? 243 THR A C   1 
ATOM   1857 O O   . THR A 1 246 ? 115.264 82.081  198.110 1.00 60.95  ? 243 THR A O   1 
ATOM   1858 C CB  . THR A 1 246 ? 114.352 82.648  201.214 1.00 59.83  ? 243 THR A CB  1 
ATOM   1859 O OG1 . THR A 1 246 ? 114.848 83.296  202.384 1.00 60.64  ? 243 THR A OG1 1 
ATOM   1860 C CG2 . THR A 1 246 ? 114.965 81.262  201.164 1.00 56.27  ? 243 THR A CG2 1 
ATOM   1861 N N   . ASP A 1 247 ? 113.207 83.012  198.179 1.00 67.46  ? 244 ASP A N   1 
ATOM   1862 C CA  . ASP A 1 247 ? 112.885 82.569  196.824 1.00 61.26  ? 244 ASP A CA  1 
ATOM   1863 C C   . ASP A 1 247 ? 113.886 83.124  195.829 1.00 65.48  ? 244 ASP A C   1 
ATOM   1864 O O   . ASP A 1 247 ? 114.295 82.427  194.896 1.00 70.73  ? 244 ASP A O   1 
ATOM   1865 C CB  . ASP A 1 247 ? 111.464 82.980  196.419 1.00 63.02  ? 244 ASP A CB  1 
ATOM   1866 C CG  . ASP A 1 247 ? 110.372 82.313  197.270 1.00 70.64  ? 244 ASP A CG  1 
ATOM   1867 O OD1 . ASP A 1 247 ? 110.680 81.483  198.166 1.00 73.10  ? 244 ASP A OD1 1 
ATOM   1868 O OD2 . ASP A 1 247 ? 109.182 82.617  197.030 1.00 63.49  ? 244 ASP A OD2 1 
ATOM   1869 N N   . ALA A 1 248 ? 114.299 84.380  196.013 1.00 67.37  ? 245 ALA A N   1 
ATOM   1870 C CA  . ALA A 1 248 ? 115.279 84.974  195.108 1.00 62.91  ? 245 ALA A CA  1 
ATOM   1871 C C   . ALA A 1 248 ? 116.665 84.362  195.301 1.00 60.40  ? 245 ALA A C   1 
ATOM   1872 O O   . ALA A 1 248 ? 117.284 83.916  194.336 1.00 60.13  ? 245 ALA A O   1 
ATOM   1873 C CB  . ALA A 1 248 ? 115.310 86.488  195.300 1.00 62.86  ? 245 ALA A CB  1 
ATOM   1874 N N   . VAL A 1 249 ? 117.152 84.285  196.546 1.00 61.29  ? 246 VAL A N   1 
ATOM   1875 C CA  . VAL A 1 249 ? 118.503 83.772  196.798 1.00 56.82  ? 246 VAL A CA  1 
ATOM   1876 C C   . VAL A 1 249 ? 118.618 82.315  196.383 1.00 60.90  ? 246 VAL A C   1 
ATOM   1877 O O   . VAL A 1 249 ? 119.676 81.869  195.924 1.00 62.17  ? 246 VAL A O   1 
ATOM   1878 C CB  . VAL A 1 249 ? 118.902 83.947  198.273 1.00 57.91  ? 246 VAL A CB  1 
ATOM   1879 C CG1 . VAL A 1 249 ? 120.142 83.137  198.574 1.00 55.10  ? 246 VAL A CG1 1 
ATOM   1880 C CG2 . VAL A 1 249 ? 119.174 85.398  198.586 1.00 58.80  ? 246 VAL A CG2 1 
ATOM   1881 N N   . PHE A 1 250 ? 117.550 81.537  196.553 1.00 62.46  ? 247 PHE A N   1 
ATOM   1882 C CA  . PHE A 1 250 ? 117.640 80.129  196.187 1.00 60.11  ? 247 PHE A CA  1 
ATOM   1883 C C   . PHE A 1 250 ? 117.749 79.924  194.677 1.00 61.36  ? 247 PHE A C   1 
ATOM   1884 O O   . PHE A 1 250 ? 118.171 78.847  194.235 1.00 61.10  ? 247 PHE A O   1 
ATOM   1885 C CB  . PHE A 1 250 ? 116.437 79.352  196.734 1.00 58.42  ? 247 PHE A CB  1 
ATOM   1886 C CG  . PHE A 1 250 ? 116.703 78.661  198.031 1.00 54.09  ? 247 PHE A CG  1 
ATOM   1887 C CD1 . PHE A 1 250 ? 116.972 79.389  199.185 1.00 59.19  ? 247 PHE A CD1 1 
ATOM   1888 C CD2 . PHE A 1 250 ? 116.713 77.283  198.094 1.00 49.58  ? 247 PHE A CD2 1 
ATOM   1889 C CE1 . PHE A 1 250 ? 117.214 78.756  200.400 1.00 51.22  ? 247 PHE A CE1 1 
ATOM   1890 C CE2 . PHE A 1 250 ? 116.968 76.647  199.282 1.00 56.00  ? 247 PHE A CE2 1 
ATOM   1891 C CZ  . PHE A 1 250 ? 117.216 77.392  200.449 1.00 54.61  ? 247 PHE A CZ  1 
ATOM   1892 N N   . SER A 1 251 ? 117.388 80.923  193.876 1.00 63.42  ? 248 SER A N   1 
ATOM   1893 C CA  . SER A 1 251 ? 117.520 80.803  192.428 1.00 63.13  ? 248 SER A CA  1 
ATOM   1894 C C   . SER A 1 251 ? 118.944 81.048  191.939 1.00 61.94  ? 248 SER A C   1 
ATOM   1895 O O   . SER A 1 251 ? 119.182 80.992  190.725 1.00 63.83  ? 248 SER A O   1 
ATOM   1896 C CB  . SER A 1 251 ? 116.558 81.762  191.727 1.00 63.64  ? 248 SER A CB  1 
ATOM   1897 O OG  . SER A 1 251 ? 117.056 83.078  191.770 1.00 69.03  ? 248 SER A OG  1 
ATOM   1898 N N   . MET A 1 252 ? 119.889 81.333  192.844 1.00 62.29  ? 249 MET A N   1 
ATOM   1899 C CA  . MET A 1 252 ? 121.256 81.680  192.468 1.00 57.27  ? 249 MET A CA  1 
ATOM   1900 C C   . MET A 1 252 ? 122.278 81.025  193.385 1.00 57.23  ? 249 MET A C   1 
ATOM   1901 O O   . MET A 1 252 ? 123.293 81.637  193.737 1.00 57.70  ? 249 MET A O   1 
ATOM   1902 C CB  . MET A 1 252 ? 121.464 83.191  192.479 1.00 60.29  ? 249 MET A CB  1 
ATOM   1903 C CG  . MET A 1 252 ? 121.066 83.890  193.745 1.00 61.49  ? 249 MET A CG  1 
ATOM   1904 S SD  . MET A 1 252 ? 121.105 85.664  193.471 1.00 72.58  ? 249 MET A SD  1 
ATOM   1905 C CE  . MET A 1 252 ? 119.792 85.817  192.256 1.00 62.09  ? 249 MET A CE  1 
ATOM   1906 N N   . LEU A 1 253 ? 122.037 79.774  193.786 1.00 55.65  ? 250 LEU A N   1 
ATOM   1907 C CA  . LEU A 1 253 ? 122.944 79.095  194.708 1.00 57.50  ? 250 LEU A CA  1 
ATOM   1908 C C   . LEU A 1 253 ? 124.145 78.498  193.976 1.00 48.48  ? 250 LEU A C   1 
ATOM   1909 O O   . LEU A 1 253 ? 123.985 77.677  193.074 1.00 47.44  ? 250 LEU A O   1 
ATOM   1910 C CB  . LEU A 1 253 ? 122.197 78.005  195.483 1.00 56.18  ? 250 LEU A CB  1 
ATOM   1911 C CG  . LEU A 1 253 ? 121.130 78.462  196.479 1.00 53.35  ? 250 LEU A CG  1 
ATOM   1912 C CD1 . LEU A 1 253 ? 120.447 77.276  197.163 1.00 48.47  ? 250 LEU A CD1 1 
ATOM   1913 C CD2 . LEU A 1 253 ? 121.773 79.386  197.480 1.00 50.30  ? 250 LEU A CD2 1 
ATOM   1914 N N   . ASN A 1 254 ? 125.347 78.856  194.413 1.00 46.50  ? 251 ASN A N   1 
ATOM   1915 C CA  . ASN A 1 254 ? 126.554 78.259  193.862 1.00 49.06  ? 251 ASN A CA  1 
ATOM   1916 C C   . ASN A 1 254 ? 126.675 76.795  194.295 1.00 51.74  ? 251 ASN A C   1 
ATOM   1917 O O   . ASN A 1 254 ? 125.975 76.330  195.194 1.00 60.64  ? 251 ASN A O   1 
ATOM   1918 C CB  . ASN A 1 254 ? 127.790 79.019  194.341 1.00 59.40  ? 251 ASN A CB  1 
ATOM   1919 C CG  . ASN A 1 254 ? 127.909 80.408  193.748 1.00 61.16  ? 251 ASN A CG  1 
ATOM   1920 O OD1 . ASN A 1 254 ? 127.512 80.648  192.613 1.00 66.28  ? 251 ASN A OD1 1 
ATOM   1921 N ND2 . ASN A 1 254 ? 128.455 81.338  194.531 1.00 60.70  ? 251 ASN A ND2 1 
ATOM   1922 N N   . VAL A 1 255 ? 127.587 76.054  193.659 1.00 48.80  ? 252 VAL A N   1 
ATOM   1923 C CA  . VAL A 1 255 ? 127.852 74.692  194.106 1.00 48.28  ? 252 VAL A CA  1 
ATOM   1924 C C   . VAL A 1 255 ? 128.440 74.713  195.503 1.00 47.66  ? 252 VAL A C   1 
ATOM   1925 O O   . VAL A 1 255 ? 129.273 75.566  195.829 1.00 50.17  ? 252 VAL A O   1 
ATOM   1926 C CB  . VAL A 1 255 ? 128.792 73.963  193.134 1.00 48.25  ? 252 VAL A CB  1 
ATOM   1927 C CG1 . VAL A 1 255 ? 129.210 72.638  193.733 1.00 47.32  ? 252 VAL A CG1 1 
ATOM   1928 C CG2 . VAL A 1 255 ? 128.099 73.738  191.785 1.00 48.06  ? 252 VAL A CG2 1 
ATOM   1929 N N   . GLY A 1 256 ? 128.019 73.758  196.333 1.00 45.58  ? 253 GLY A N   1 
ATOM   1930 C CA  . GLY A 1 256 ? 128.586 73.610  197.659 1.00 50.79  ? 253 GLY A CA  1 
ATOM   1931 C C   . GLY A 1 256 ? 128.125 74.640  198.661 1.00 53.95  ? 253 GLY A C   1 
ATOM   1932 O O   . GLY A 1 256 ? 128.742 74.800  199.721 1.00 51.12  ? 253 GLY A O   1 
ATOM   1933 N N   . SER A 1 257 ? 127.047 75.346  198.351 1.00 55.57  ? 254 SER A N   1 
ATOM   1934 C CA  . SER A 1 257 ? 126.589 76.430  199.191 1.00 53.91  ? 254 SER A CA  1 
ATOM   1935 C C   . SER A 1 257 ? 125.946 75.872  200.450 1.00 50.97  ? 254 SER A C   1 
ATOM   1936 O O   . SER A 1 257 ? 125.657 74.673  200.557 1.00 51.17  ? 254 SER A O   1 
ATOM   1937 C CB  . SER A 1 257 ? 125.603 77.309  198.430 1.00 54.95  ? 254 SER A CB  1 
ATOM   1938 O OG  . SER A 1 257 ? 124.707 76.507  197.676 1.00 52.29  ? 254 SER A OG  1 
ATOM   1939 N N   . GLN A 1 258 ? 125.754 76.765  201.422 1.00 52.59  ? 255 GLN A N   1 
ATOM   1940 C CA  . GLN A 1 258 ? 125.155 76.438  202.715 1.00 54.51  ? 255 GLN A CA  1 
ATOM   1941 C C   . GLN A 1 258 ? 124.165 77.533  203.076 1.00 57.42  ? 255 GLN A C   1 
ATOM   1942 O O   . GLN A 1 258 ? 124.551 78.697  203.222 1.00 56.09  ? 255 GLN A O   1 
ATOM   1943 C CB  . GLN A 1 258 ? 126.210 76.306  203.815 1.00 47.17  ? 255 GLN A CB  1 
ATOM   1944 C CG  . GLN A 1 258 ? 127.439 75.555  203.400 1.00 49.83  ? 255 GLN A CG  1 
ATOM   1945 C CD  . GLN A 1 258 ? 128.424 75.375  204.523 1.00 52.63  ? 255 GLN A CD  1 
ATOM   1946 O OE1 . GLN A 1 258 ? 129.044 76.330  204.976 1.00 55.06  ? 255 GLN A OE1 1 
ATOM   1947 N NE2 . GLN A 1 258 ? 128.570 74.143  204.989 1.00 55.65  ? 255 GLN A NE2 1 
ATOM   1948 N N   . VAL A 1 259 ? 122.891 77.158  203.216 1.00 54.19  ? 256 VAL A N   1 
ATOM   1949 C CA  . VAL A 1 259 ? 121.854 78.045  203.726 1.00 52.14  ? 256 VAL A CA  1 
ATOM   1950 C C   . VAL A 1 259 ? 121.736 77.758  205.209 1.00 48.66  ? 256 VAL A C   1 
ATOM   1951 O O   . VAL A 1 259 ? 121.940 76.621  205.633 1.00 52.74  ? 256 VAL A O   1 
ATOM   1952 C CB  . VAL A 1 259 ? 120.509 77.842  202.990 1.00 52.56  ? 256 VAL A CB  1 
ATOM   1953 C CG1 . VAL A 1 259 ? 119.478 78.852  203.441 1.00 49.99  ? 256 VAL A CG1 1 
ATOM   1954 C CG2 . VAL A 1 259 ? 120.688 78.027  201.508 1.00 50.82  ? 256 VAL A CG2 1 
ATOM   1955 N N   . ALA A 1 260 ? 121.474 78.791  206.008 1.00 50.56  ? 257 ALA A N   1 
ATOM   1956 C CA  . ALA A 1 260 ? 121.155 78.646  207.427 1.00 47.57  ? 257 ALA A CA  1 
ATOM   1957 C C   . ALA A 1 260 ? 119.823 79.341  207.651 1.00 48.65  ? 257 ALA A C   1 
ATOM   1958 O O   . ALA A 1 260 ? 119.744 80.574  207.630 1.00 50.34  ? 257 ALA A O   1 
ATOM   1959 C CB  . ALA A 1 260 ? 122.247 79.223  208.320 1.00 42.39  ? 257 ALA A CB  1 
ATOM   1960 N N   . VAL A 1 261 ? 118.768 78.549  207.806 1.00 48.48  ? 258 VAL A N   1 
ATOM   1961 C CA  . VAL A 1 261 ? 117.453 79.076  208.158 1.00 50.99  ? 258 VAL A CA  1 
ATOM   1962 C C   . VAL A 1 261 ? 117.413 79.312  209.668 1.00 52.17  ? 258 VAL A C   1 
ATOM   1963 O O   . VAL A 1 261 ? 117.451 78.370  210.463 1.00 49.09  ? 258 VAL A O   1 
ATOM   1964 C CB  . VAL A 1 261 ? 116.332 78.131  207.723 1.00 50.82  ? 258 VAL A CB  1 
ATOM   1965 C CG1 . VAL A 1 261 ? 114.996 78.825  207.872 1.00 50.53  ? 258 VAL A CG1 1 
ATOM   1966 C CG2 . VAL A 1 261 ? 116.574 77.645  206.317 1.00 48.36  ? 258 VAL A CG2 1 
ATOM   1967 N N   . CYS A 1 262 ? 117.294 80.571  210.059 1.00 51.62  ? 259 CYS A N   1 
ATOM   1968 C CA  . CYS A 1 262 ? 117.337 80.997  211.449 1.00 53.14  ? 259 CYS A CA  1 
ATOM   1969 C C   . CYS A 1 262 ? 115.977 81.427  211.987 1.00 57.63  ? 259 CYS A C   1 
ATOM   1970 O O   . CYS A 1 262 ? 115.634 81.108  213.125 1.00 58.80  ? 259 CYS A O   1 
ATOM   1971 C CB  . CYS A 1 262 ? 118.341 82.143  211.583 1.00 53.64  ? 259 CYS A CB  1 
ATOM   1972 S SG  . CYS A 1 262 ? 118.253 83.023  213.107 1.00 56.60  ? 259 CYS A SG  1 
ATOM   1973 N N   . TRP A 1 263 ? 115.223 82.195  211.209 1.00 58.66  ? 260 TRP A N   1 
ATOM   1974 C CA  . TRP A 1 263 ? 113.825 82.514  211.462 1.00 58.26  ? 260 TRP A CA  1 
ATOM   1975 C C   . TRP A 1 263 ? 113.197 82.753  210.094 1.00 58.14  ? 260 TRP A C   1 
ATOM   1976 O O   . TRP A 1 263 ? 113.884 82.727  209.069 1.00 57.38  ? 260 TRP A O   1 
ATOM   1977 C CB  . TRP A 1 263 ? 113.682 83.710  212.420 1.00 59.15  ? 260 TRP A CB  1 
ATOM   1978 C CG  . TRP A 1 263 ? 112.372 83.753  213.119 1.00 60.16  ? 260 TRP A CG  1 
ATOM   1979 C CD1 . TRP A 1 263 ? 111.811 82.753  213.849 1.00 62.54  ? 260 TRP A CD1 1 
ATOM   1980 C CD2 . TRP A 1 263 ? 111.464 84.863  213.196 1.00 62.35  ? 260 TRP A CD2 1 
ATOM   1981 N NE1 . TRP A 1 263 ? 110.592 83.153  214.351 1.00 68.02  ? 260 TRP A NE1 1 
ATOM   1982 C CE2 . TRP A 1 263 ? 110.357 84.447  213.967 1.00 63.25  ? 260 TRP A CE2 1 
ATOM   1983 C CE3 . TRP A 1 263 ? 111.469 86.159  212.680 1.00 59.96  ? 260 TRP A CE3 1 
ATOM   1984 C CZ2 . TRP A 1 263 ? 109.270 85.278  214.230 1.00 56.25  ? 260 TRP A CZ2 1 
ATOM   1985 C CZ3 . TRP A 1 263 ? 110.382 86.982  212.947 1.00 61.85  ? 260 TRP A CZ3 1 
ATOM   1986 C CH2 . TRP A 1 263 ? 109.302 86.536  213.712 1.00 57.41  ? 260 TRP A CH2 1 
ATOM   1987 N N   . GLN A 1 264 ? 111.881 82.940  210.056 1.00 57.50  ? 261 GLN A N   1 
ATOM   1988 C CA  . GLN A 1 264 ? 111.218 83.199  208.774 1.00 59.35  ? 261 GLN A CA  1 
ATOM   1989 C C   . GLN A 1 264 ? 110.205 84.328  208.962 1.00 63.07  ? 261 GLN A C   1 
ATOM   1990 O O   . GLN A 1 264 ? 108.998 84.098  208.940 1.00 64.90  ? 261 GLN A O   1 
ATOM   1991 C CB  . GLN A 1 264 ? 110.553 81.937  208.216 1.00 57.97  ? 261 GLN A CB  1 
ATOM   1992 C CG  . GLN A 1 264 ? 111.527 80.818  207.908 1.00 55.67  ? 261 GLN A CG  1 
ATOM   1993 C CD  . GLN A 1 264 ? 112.173 80.959  206.562 1.00 51.75  ? 261 GLN A CD  1 
ATOM   1994 O OE1 . GLN A 1 264 ? 111.722 80.366  205.597 1.00 52.17  ? 261 GLN A OE1 1 
ATOM   1995 N NE2 . GLN A 1 264 ? 113.214 81.773  206.478 1.00 53.84  ? 261 GLN A NE2 1 
ATOM   1996 N N   . TRP A 1 265 ? 110.720 85.556  209.127 1.00 64.22  ? 262 TRP A N   1 
ATOM   1997 C CA  . TRP A 1 265 ? 109.855 86.707  209.382 1.00 62.93  ? 262 TRP A CA  1 
ATOM   1998 C C   . TRP A 1 265 ? 108.692 86.740  208.410 1.00 63.85  ? 262 TRP A C   1 
ATOM   1999 O O   . TRP A 1 265 ? 107.550 86.992  208.806 1.00 66.75  ? 262 TRP A O   1 
ATOM   2000 C CB  . TRP A 1 265 ? 110.636 88.020  209.283 1.00 60.99  ? 262 TRP A CB  1 
ATOM   2001 C CG  . TRP A 1 265 ? 109.792 89.259  209.573 1.00 67.51  ? 262 TRP A CG  1 
ATOM   2002 C CD1 . TRP A 1 265 ? 108.713 89.716  208.857 1.00 71.28  ? 262 TRP A CD1 1 
ATOM   2003 C CD2 . TRP A 1 265 ? 110.003 90.225  210.618 1.00 67.60  ? 262 TRP A CD2 1 
ATOM   2004 N NE1 . TRP A 1 265 ? 108.221 90.877  209.412 1.00 71.93  ? 262 TRP A NE1 1 
ATOM   2005 C CE2 . TRP A 1 265 ? 108.999 91.215  210.487 1.00 70.53  ? 262 TRP A CE2 1 
ATOM   2006 C CE3 . TRP A 1 265 ? 110.938 90.351  211.645 1.00 63.96  ? 262 TRP A CE3 1 
ATOM   2007 C CZ2 . TRP A 1 265 ? 108.908 92.306  211.349 1.00 66.35  ? 262 TRP A CZ2 1 
ATOM   2008 C CZ3 . TRP A 1 265 ? 110.835 91.435  212.498 1.00 67.89  ? 262 TRP A CZ3 1 
ATOM   2009 C CH2 . TRP A 1 265 ? 109.833 92.399  212.342 1.00 63.45  ? 262 TRP A CH2 1 
ATOM   2010 N N   . ALA A 1 266 ? 108.960 86.470  207.135 1.00 59.37  ? 263 ALA A N   1 
ATOM   2011 C CA  . ALA A 1 266 ? 107.932 86.663  206.131 1.00 58.85  ? 263 ALA A CA  1 
ATOM   2012 C C   . ALA A 1 266 ? 106.756 85.723  206.304 1.00 59.67  ? 263 ALA A C   1 
ATOM   2013 O O   . ALA A 1 266 ? 105.658 86.044  205.845 1.00 60.40  ? 263 ALA A O   1 
ATOM   2014 C CB  . ALA A 1 266 ? 108.531 86.490  204.748 1.00 59.10  ? 263 ALA A CB  1 
ATOM   2015 N N   . THR A 1 267 ? 106.941 84.590  206.970 1.00 62.21  ? 264 THR A N   1 
ATOM   2016 C CA  . THR A 1 267 ? 105.823 83.679  207.190 1.00 63.76  ? 264 THR A CA  1 
ATOM   2017 C C   . THR A 1 267 ? 105.182 83.830  208.571 1.00 65.54  ? 264 THR A C   1 
ATOM   2018 O O   . THR A 1 267 ? 103.953 83.769  208.681 1.00 69.39  ? 264 THR A O   1 
ATOM   2019 C CB  . THR A 1 267 ? 106.255 82.227  206.967 1.00 62.74  ? 264 THR A CB  1 
ATOM   2020 O OG1 . THR A 1 267 ? 107.097 82.149  205.808 1.00 63.96  ? 264 THR A OG1 1 
ATOM   2021 C CG2 . THR A 1 267 ? 105.028 81.370  206.713 1.00 59.11  ? 264 THR A CG2 1 
ATOM   2022 N N   . GLN A 1 268 ? 105.975 83.985  209.637 1.00 62.99  ? 265 GLN A N   1 
ATOM   2023 C CA  . GLN A 1 268 ? 105.406 84.237  210.961 1.00 63.95  ? 265 GLN A CA  1 
ATOM   2024 C C   . GLN A 1 268 ? 104.617 85.534  210.983 1.00 65.15  ? 265 GLN A C   1 
ATOM   2025 O O   . GLN A 1 268 ? 103.418 85.544  211.277 1.00 68.27  ? 265 GLN A O   1 
ATOM   2026 C CB  . GLN A 1 268 ? 106.508 84.289  212.025 1.00 64.90  ? 265 GLN A CB  1 
ATOM   2027 C CG  . GLN A 1 268 ? 106.932 82.954  212.569 1.00 63.07  ? 265 GLN A CG  1 
ATOM   2028 C CD  . GLN A 1 268 ? 105.861 82.357  213.442 1.00 60.15  ? 265 GLN A CD  1 
ATOM   2029 O OE1 . GLN A 1 268 ? 104.917 83.047  213.841 1.00 57.91  ? 265 GLN A OE1 1 
ATOM   2030 N NE2 . GLN A 1 268 ? 105.995 81.072  213.752 1.00 59.28  ? 265 GLN A NE2 1 
ATOM   2031 N N   . VAL A 1 269 ? 105.287 86.649  210.694 1.00 66.59  ? 266 VAL A N   1 
ATOM   2032 C CA  . VAL A 1 269 ? 104.685 87.961  210.895 1.00 66.61  ? 266 VAL A CA  1 
ATOM   2033 C C   . VAL A 1 269 ? 103.750 88.317  209.743 1.00 67.76  ? 266 VAL A C   1 
ATOM   2034 O O   . VAL A 1 269 ? 102.618 88.745  209.966 1.00 74.23  ? 266 VAL A O   1 
ATOM   2035 C CB  . VAL A 1 269 ? 105.781 89.025  211.093 1.00 66.04  ? 266 VAL A CB  1 
ATOM   2036 C CG1 . VAL A 1 269 ? 105.153 90.384  211.356 1.00 65.31  ? 266 VAL A CG1 1 
ATOM   2037 C CG2 . VAL A 1 269 ? 106.755 88.613  212.203 1.00 61.59  ? 266 VAL A CG2 1 
ATOM   2038 N N   . GLN A 1 270 ? 104.198 88.166  208.496 1.00 72.22  ? 267 GLN A N   1 
ATOM   2039 C CA  . GLN A 1 270 ? 103.448 88.659  207.341 1.00 69.17  ? 267 GLN A CA  1 
ATOM   2040 C C   . GLN A 1 270 ? 102.743 87.563  206.572 1.00 68.77  ? 267 GLN A C   1 
ATOM   2041 O O   . GLN A 1 270 ? 102.169 87.835  205.514 1.00 73.02  ? 267 GLN A O   1 
ATOM   2042 C CB  . GLN A 1 270 ? 104.371 89.433  206.407 1.00 66.47  ? 267 GLN A CB  1 
ATOM   2043 C CG  . GLN A 1 270 ? 104.859 90.698  207.058 1.00 73.77  ? 267 GLN A CG  1 
ATOM   2044 C CD  . GLN A 1 270 ? 106.066 91.254  206.381 1.00 79.72  ? 267 GLN A CD  1 
ATOM   2045 O OE1 . GLN A 1 270 ? 106.770 90.540  205.661 1.00 73.48  ? 267 GLN A OE1 1 
ATOM   2046 N NE2 . GLN A 1 270 ? 106.350 92.530  206.635 1.00 88.74  ? 267 GLN A NE2 1 
ATOM   2047 N N   . ARG A 1 271 ? 102.808 86.331  207.065 1.00 71.60  ? 268 ARG A N   1 
ATOM   2048 C CA  . ARG A 1 271 ? 101.893 85.257  206.680 1.00 71.28  ? 268 ARG A CA  1 
ATOM   2049 C C   . ARG A 1 271 ? 102.013 84.840  205.204 1.00 66.23  ? 268 ARG A C   1 
ATOM   2050 O O   . ARG A 1 271 ? 101.018 84.561  204.532 1.00 66.04  ? 268 ARG A O   1 
ATOM   2051 C CB  . ARG A 1 271 ? 100.470 85.659  207.063 1.00 67.16  ? 268 ARG A CB  1 
ATOM   2052 C CG  . ARG A 1 271 ? 100.442 86.234  208.483 1.00 64.18  ? 268 ARG A CG  1 
ATOM   2053 C CD  . ARG A 1 271 ? 99.052  86.565  208.936 1.00 66.18  ? 268 ARG A CD  1 
ATOM   2054 N NE  . ARG A 1 271 ? 98.435  85.343  209.438 1.00 67.11  ? 268 ARG A NE  1 
ATOM   2055 C CZ  . ARG A 1 271 ? 97.166  85.237  209.797 1.00 69.80  ? 268 ARG A CZ  1 
ATOM   2056 N NH1 . ARG A 1 271 ? 96.338  86.268  209.702 1.00 69.93  ? 268 ARG A NH1 1 
ATOM   2057 N NH2 . ARG A 1 271 ? 96.716  84.070  210.257 1.00 58.95  ? 268 ARG A NH2 1 
ATOM   2058 N N   . ASP A 1 272 ? 103.252 84.739  204.713 1.00 63.57  ? 269 ASP A N   1 
ATOM   2059 C CA  . ASP A 1 272 ? 103.548 84.229  203.371 1.00 64.43  ? 269 ASP A CA  1 
ATOM   2060 C C   . ASP A 1 272 ? 103.595 82.707  203.472 1.00 66.07  ? 269 ASP A C   1 
ATOM   2061 O O   . ASP A 1 272 ? 104.656 82.083  203.477 1.00 67.90  ? 269 ASP A O   1 
ATOM   2062 C CB  . ASP A 1 272 ? 104.878 84.795  202.873 1.00 64.71  ? 269 ASP A CB  1 
ATOM   2063 C CG  . ASP A 1 272 ? 105.147 84.521  201.387 1.00 68.51  ? 269 ASP A CG  1 
ATOM   2064 O OD1 . ASP A 1 272 ? 104.444 83.683  200.771 1.00 68.15  ? 269 ASP A OD1 1 
ATOM   2065 O OD2 . ASP A 1 272 ? 106.098 85.146  200.847 1.00 66.73  ? 269 ASP A OD2 1 
ATOM   2066 N N   . TYR A 1 273 ? 102.417 82.092  203.500 1.00 65.39  ? 270 TYR A N   1 
ATOM   2067 C CA  . TYR A 1 273 ? 102.355 80.663  203.758 1.00 61.94  ? 270 TYR A CA  1 
ATOM   2068 C C   . TYR A 1 273 ? 102.500 79.793  202.515 1.00 63.27  ? 270 TYR A C   1 
ATOM   2069 O O   . TYR A 1 273 ? 102.681 78.581  202.658 1.00 62.95  ? 270 TYR A O   1 
ATOM   2070 C CB  . TYR A 1 273 ? 101.037 80.306  204.441 1.00 62.32  ? 270 TYR A CB  1 
ATOM   2071 C CG  . TYR A 1 273 ? 100.828 80.942  205.798 1.00 69.86  ? 270 TYR A CG  1 
ATOM   2072 C CD1 . TYR A 1 273 ? 101.602 80.562  206.901 1.00 72.56  ? 270 TYR A CD1 1 
ATOM   2073 C CD2 . TYR A 1 273 ? 99.796  81.854  206.008 1.00 70.60  ? 270 TYR A CD2 1 
ATOM   2074 C CE1 . TYR A 1 273 ? 101.403 81.126  208.175 1.00 69.14  ? 270 TYR A CE1 1 
ATOM   2075 C CE2 . TYR A 1 273 ? 99.580  82.414  207.274 1.00 77.46  ? 270 TYR A CE2 1 
ATOM   2076 C CZ  . TYR A 1 273 ? 100.389 82.044  208.354 1.00 73.64  ? 270 TYR A CZ  1 
ATOM   2077 O OH  . TYR A 1 273 ? 100.170 82.598  209.596 1.00 67.91  ? 270 TYR A OH  1 
ATOM   2078 N N   . HIS A 1 274 ? 102.413 80.354  201.311 1.00 66.53  ? 271 HIS A N   1 
ATOM   2079 C CA  . HIS A 1 274 ? 102.467 79.566  200.083 1.00 64.61  ? 271 HIS A CA  1 
ATOM   2080 C C   . HIS A 1 274 ? 103.334 80.309  199.076 1.00 65.78  ? 271 HIS A C   1 
ATOM   2081 O O   . HIS A 1 274 ? 103.238 81.536  198.955 1.00 73.40  ? 271 HIS A O   1 
ATOM   2082 C CB  . HIS A 1 274 ? 101.050 79.310  199.535 1.00 64.75  ? 271 HIS A CB  1 
ATOM   2083 C CG  . HIS A 1 274 ? 100.960 78.229  198.496 1.00 67.54  ? 271 HIS A CG  1 
ATOM   2084 N ND1 . HIS A 1 274 ? 100.375 77.004  198.745 1.00 68.55  ? 271 HIS A ND1 1 
ATOM   2085 C CD2 . HIS A 1 274 ? 101.327 78.206  197.190 1.00 70.90  ? 271 HIS A CD2 1 
ATOM   2086 C CE1 . HIS A 1 274 ? 100.407 76.267  197.647 1.00 63.97  ? 271 HIS A CE1 1 
ATOM   2087 N NE2 . HIS A 1 274 ? 100.983 76.971  196.690 1.00 65.81  ? 271 HIS A NE2 1 
ATOM   2088 N N   . GLY A 1 275 ? 104.186 79.570  198.371 1.00 58.88  ? 272 GLY A N   1 
ATOM   2089 C CA  . GLY A 1 275 ? 105.091 80.157  197.417 1.00 56.15  ? 272 GLY A CA  1 
ATOM   2090 C C   . GLY A 1 275 ? 105.723 79.099  196.544 1.00 59.63  ? 272 GLY A C   1 
ATOM   2091 O O   . GLY A 1 275 ? 105.380 77.915  196.623 1.00 60.29  ? 272 GLY A O   1 
ATOM   2092 N N   . PRO A 1 276 ? 106.642 79.511  195.671 1.00 61.81  ? 273 PRO A N   1 
ATOM   2093 C CA  . PRO A 1 276 ? 107.382 78.538  194.856 1.00 58.86  ? 273 PRO A CA  1 
ATOM   2094 C C   . PRO A 1 276 ? 108.179 77.549  195.694 1.00 57.21  ? 273 PRO A C   1 
ATOM   2095 O O   . PRO A 1 276 ? 108.829 77.915  196.679 1.00 58.09  ? 273 PRO A O   1 
ATOM   2096 C CB  . PRO A 1 276 ? 108.319 79.423  194.024 1.00 53.13  ? 273 PRO A CB  1 
ATOM   2097 C CG  . PRO A 1 276 ? 108.422 80.684  194.778 1.00 57.81  ? 273 PRO A CG  1 
ATOM   2098 C CD  . PRO A 1 276 ? 107.049 80.887  195.358 1.00 62.87  ? 273 PRO A CD  1 
ATOM   2099 N N   . ARG A 1 277 ? 108.167 76.294  195.250 1.00 51.73  ? 274 ARG A N   1 
ATOM   2100 C CA  . ARG A 1 277 ? 108.941 75.247  195.895 1.00 49.91  ? 274 ARG A CA  1 
ATOM   2101 C C   . ARG A 1 277 ? 110.427 75.519  195.739 1.00 49.00  ? 274 ARG A C   1 
ATOM   2102 O O   . ARG A 1 277 ? 110.908 75.734  194.635 1.00 48.02  ? 274 ARG A O   1 
ATOM   2103 C CB  . ARG A 1 277 ? 108.581 73.882  195.323 1.00 48.17  ? 274 ARG A CB  1 
ATOM   2104 C CG  . ARG A 1 277 ? 107.115 73.551  195.452 1.00 50.12  ? 274 ARG A CG  1 
ATOM   2105 C CD  . ARG A 1 277 ? 106.875 72.054  195.348 1.00 53.76  ? 274 ARG A CD  1 
ATOM   2106 N NE  . ARG A 1 277 ? 105.505 71.725  195.725 1.00 57.88  ? 274 ARG A NE  1 
ATOM   2107 C CZ  . ARG A 1 277 ? 105.156 70.959  196.750 1.00 56.06  ? 274 ARG A CZ  1 
ATOM   2108 N NH1 . ARG A 1 277 ? 106.060 70.378  197.518 1.00 56.31  ? 274 ARG A NH1 1 
ATOM   2109 N NH2 . ARG A 1 277 ? 103.864 70.779  197.012 1.00 55.83  ? 274 ARG A NH2 1 
ATOM   2110 N N   . LEU A 1 278 ? 111.154 75.546  196.850 1.00 57.61  ? 275 LEU A N   1 
ATOM   2111 C CA  . LEU A 1 278 ? 112.568 75.867  196.777 1.00 53.07  ? 275 LEU A CA  1 
ATOM   2112 C C   . LEU A 1 278 ? 113.444 74.635  196.650 1.00 49.97  ? 275 LEU A C   1 
ATOM   2113 O O   . LEU A 1 278 ? 114.594 74.760  196.235 1.00 51.55  ? 275 LEU A O   1 
ATOM   2114 C CB  . LEU A 1 278 ? 113.007 76.656  198.016 1.00 51.09  ? 275 LEU A CB  1 
ATOM   2115 C CG  . LEU A 1 278 ? 112.306 77.982  198.297 1.00 50.83  ? 275 LEU A CG  1 
ATOM   2116 C CD1 . LEU A 1 278 ? 113.125 78.832  199.218 1.00 56.92  ? 275 LEU A CD1 1 
ATOM   2117 C CD2 . LEU A 1 278 ? 111.997 78.728  197.045 1.00 61.68  ? 275 LEU A CD2 1 
ATOM   2118 N N   . LEU A 1 279 ? 112.938 73.458  196.995 1.00 48.46  ? 276 LEU A N   1 
ATOM   2119 C CA  . LEU A 1 279 ? 113.802 72.282  197.019 1.00 48.92  ? 276 LEU A CA  1 
ATOM   2120 C C   . LEU A 1 279 ? 114.360 71.884  195.667 1.00 56.22  ? 276 LEU A C   1 
ATOM   2121 O O   . LEU A 1 279 ? 115.509 71.408  195.628 1.00 62.52  ? 276 LEU A O   1 
ATOM   2122 C CB  . LEU A 1 279 ? 113.071 71.103  197.668 1.00 48.87  ? 276 LEU A CB  1 
ATOM   2123 C CG  . LEU A 1 279 ? 113.197 71.188  199.188 1.00 47.65  ? 276 LEU A CG  1 
ATOM   2124 C CD1 . LEU A 1 279 ? 112.703 69.932  199.865 1.00 49.64  ? 276 LEU A CD1 1 
ATOM   2125 C CD2 . LEU A 1 279 ? 114.632 71.432  199.541 1.00 47.78  ? 276 LEU A CD2 1 
ATOM   2126 N N   . PRO A 1 280 ? 113.648 72.025  194.549 1.00 56.84  ? 277 PRO A N   1 
ATOM   2127 C CA  . PRO A 1 280 ? 114.279 71.699  193.261 1.00 51.39  ? 277 PRO A CA  1 
ATOM   2128 C C   . PRO A 1 280 ? 115.571 72.446  193.012 1.00 55.06  ? 277 PRO A C   1 
ATOM   2129 O O   . PRO A 1 280 ? 116.491 71.881  192.413 1.00 60.09  ? 277 PRO A O   1 
ATOM   2130 C CB  . PRO A 1 280 ? 113.201 72.090  192.254 1.00 45.17  ? 277 PRO A CB  1 
ATOM   2131 C CG  . PRO A 1 280 ? 111.960 71.819  192.964 1.00 51.31  ? 277 PRO A CG  1 
ATOM   2132 C CD  . PRO A 1 280 ? 112.197 72.233  194.383 1.00 54.22  ? 277 PRO A CD  1 
ATOM   2133 N N   . TYR A 1 281 ? 115.705 73.673  193.516 1.00 53.22  ? 278 TYR A N   1 
ATOM   2134 C CA  . TYR A 1 281 ? 116.893 74.455  193.210 1.00 54.44  ? 278 TYR A CA  1 
ATOM   2135 C C   . TYR A 1 281 ? 118.158 73.942  193.893 1.00 55.93  ? 278 TYR A C   1 
ATOM   2136 O O   . TYR A 1 281 ? 119.251 74.389  193.528 1.00 57.61  ? 278 TYR A O   1 
ATOM   2137 C CB  . TYR A 1 281 ? 116.659 75.922  193.562 1.00 52.35  ? 278 TYR A CB  1 
ATOM   2138 C CG  . TYR A 1 281 ? 115.506 76.496  192.768 1.00 60.41  ? 278 TYR A CG  1 
ATOM   2139 C CD1 . TYR A 1 281 ? 115.633 76.775  191.406 1.00 53.88  ? 278 TYR A CD1 1 
ATOM   2140 C CD2 . TYR A 1 281 ? 114.314 76.820  193.389 1.00 61.34  ? 278 TYR A CD2 1 
ATOM   2141 C CE1 . TYR A 1 281 ? 114.582 77.294  190.681 1.00 51.19  ? 278 TYR A CE1 1 
ATOM   2142 C CE2 . TYR A 1 281 ? 113.261 77.362  192.672 1.00 65.15  ? 278 TYR A CE2 1 
ATOM   2143 C CZ  . TYR A 1 281 ? 113.397 77.599  191.321 1.00 61.94  ? 278 TYR A CZ  1 
ATOM   2144 O OH  . TYR A 1 281 ? 112.326 78.134  190.632 1.00 61.20  ? 278 TYR A OH  1 
ATOM   2145 N N   . ILE A 1 282 ? 118.055 73.043  194.875 1.00 52.07  ? 279 ILE A N   1 
ATOM   2146 C CA  . ILE A 1 282 ? 119.230 72.647  195.639 1.00 51.12  ? 279 ILE A CA  1 
ATOM   2147 C C   . ILE A 1 282 ? 119.860 71.359  195.129 1.00 53.63  ? 279 ILE A C   1 
ATOM   2148 O O   . ILE A 1 282 ? 120.900 70.936  195.658 1.00 50.99  ? 279 ILE A O   1 
ATOM   2149 C CB  . ILE A 1 282 ? 118.907 72.540  197.145 1.00 50.94  ? 279 ILE A CB  1 
ATOM   2150 C CG1 . ILE A 1 282 ? 118.210 71.221  197.483 1.00 53.52  ? 279 ILE A CG1 1 
ATOM   2151 C CG2 . ILE A 1 282 ? 118.034 73.699  197.585 1.00 52.37  ? 279 ILE A CG2 1 
ATOM   2152 C CD1 . ILE A 1 282 ? 118.120 70.940  198.978 1.00 48.90  ? 279 ILE A CD1 1 
ATOM   2153 N N   . MET A 1 283 ? 119.301 70.748  194.082 1.00 54.58  ? 280 MET A N   1 
ATOM   2154 C CA  . MET A 1 283 ? 119.793 69.441  193.652 1.00 51.19  ? 280 MET A CA  1 
ATOM   2155 C C   . MET A 1 283 ? 121.117 69.531  192.907 1.00 51.99  ? 280 MET A C   1 
ATOM   2156 O O   . MET A 1 283 ? 122.058 68.807  193.232 1.00 54.37  ? 280 MET A O   1 
ATOM   2157 C CB  . MET A 1 283 ? 118.756 68.722  192.816 1.00 47.89  ? 280 MET A CB  1 
ATOM   2158 C CG  . MET A 1 283 ? 117.621 68.263  193.653 1.00 54.88  ? 280 MET A CG  1 
ATOM   2159 S SD  . MET A 1 283 ? 116.412 67.425  192.653 1.00 68.58  ? 280 MET A SD  1 
ATOM   2160 C CE  . MET A 1 283 ? 115.726 68.825  191.768 1.00 61.58  ? 280 MET A CE  1 
ATOM   2161 N N   . PHE A 1 284 ? 121.192 70.311  191.833 1.00 56.57  ? 281 PHE A N   1 
ATOM   2162 C CA  . PHE A 1 284 ? 122.489 70.413  191.165 1.00 59.62  ? 281 PHE A CA  1 
ATOM   2163 C C   . PHE A 1 284 ? 123.564 71.054  192.043 1.00 57.80  ? 281 PHE A C   1 
ATOM   2164 O O   . PHE A 1 284 ? 124.676 70.502  192.101 1.00 59.16  ? 281 PHE A O   1 
ATOM   2165 C CB  . PHE A 1 284 ? 122.402 71.133  189.806 1.00 59.58  ? 281 PHE A CB  1 
ATOM   2166 C CG  . PHE A 1 284 ? 123.760 71.402  189.200 1.00 62.88  ? 281 PHE A CG  1 
ATOM   2167 C CD1 . PHE A 1 284 ? 124.542 70.343  188.735 1.00 63.13  ? 281 PHE A CD1 1 
ATOM   2168 C CD2 . PHE A 1 284 ? 124.260 72.688  189.084 1.00 65.85  ? 281 PHE A CD2 1 
ATOM   2169 C CE1 . PHE A 1 284 ? 125.808 70.558  188.198 1.00 57.98  ? 281 PHE A CE1 1 
ATOM   2170 C CE2 . PHE A 1 284 ? 125.523 72.913  188.526 1.00 65.88  ? 281 PHE A CE2 1 
ATOM   2171 C CZ  . PHE A 1 284 ? 126.297 71.841  188.090 1.00 59.19  ? 281 PHE A CZ  1 
ATOM   2172 N N   . PRO A 1 285 ? 123.323 72.159  192.759 1.00 54.98  ? 282 PRO A N   1 
ATOM   2173 C CA  . PRO A 1 285 ? 124.413 72.761  193.539 1.00 51.97  ? 282 PRO A CA  1 
ATOM   2174 C C   . PRO A 1 285 ? 124.866 71.938  194.728 1.00 54.99  ? 282 PRO A C   1 
ATOM   2175 O O   . PRO A 1 285 ? 125.850 72.330  195.371 1.00 55.86  ? 282 PRO A O   1 
ATOM   2176 C CB  . PRO A 1 285 ? 123.804 74.081  194.033 1.00 47.56  ? 282 PRO A CB  1 
ATOM   2177 C CG  . PRO A 1 285 ? 122.618 74.304  193.195 1.00 51.11  ? 282 PRO A CG  1 
ATOM   2178 C CD  . PRO A 1 285 ? 122.093 72.964  192.847 1.00 50.79  ? 282 PRO A CD  1 
ATOM   2179 N N   . ARG A 1 286 ? 124.193 70.824  195.038 1.00 56.33  ? 283 ARG A N   1 
ATOM   2180 C CA  . ARG A 1 286 ? 124.433 70.077  196.274 1.00 54.49  ? 283 ARG A CA  1 
ATOM   2181 C C   . ARG A 1 286 ? 124.448 71.033  197.455 1.00 51.58  ? 283 ARG A C   1 
ATOM   2182 O O   . ARG A 1 286 ? 125.385 71.070  198.257 1.00 52.34  ? 283 ARG A O   1 
ATOM   2183 C CB  . ARG A 1 286 ? 125.708 69.236  196.224 1.00 51.02  ? 283 ARG A CB  1 
ATOM   2184 C CG  . ARG A 1 286 ? 125.612 68.110  195.261 1.00 49.88  ? 283 ARG A CG  1 
ATOM   2185 C CD  . ARG A 1 286 ? 125.967 68.582  193.912 1.00 53.74  ? 283 ARG A CD  1 
ATOM   2186 N NE  . ARG A 1 286 ? 127.405 68.566  193.727 1.00 59.02  ? 283 ARG A NE  1 
ATOM   2187 C CZ  . ARG A 1 286 ? 128.045 69.190  192.751 1.00 57.69  ? 283 ARG A CZ  1 
ATOM   2188 N NH1 . ARG A 1 286 ? 127.408 69.972  191.893 1.00 53.08  ? 283 ARG A NH1 1 
ATOM   2189 N NH2 . ARG A 1 286 ? 129.359 69.026  192.636 1.00 61.44  ? 283 ARG A NH2 1 
ATOM   2190 N N   . ALA A 1 287 ? 123.417 71.865  197.505 1.00 48.51  ? 284 ALA A N   1 
ATOM   2191 C CA  . ALA A 1 287 ? 123.290 72.835  198.573 1.00 51.96  ? 284 ALA A CA  1 
ATOM   2192 C C   . ALA A 1 287 ? 122.869 72.150  199.868 1.00 53.22  ? 284 ALA A C   1 
ATOM   2193 O O   . ALA A 1 287 ? 122.075 71.199  199.860 1.00 51.95  ? 284 ALA A O   1 
ATOM   2194 C CB  . ALA A 1 287 ? 122.270 73.897  198.182 1.00 52.38  ? 284 ALA A CB  1 
ATOM   2195 N N   . THR A 1 288 ? 123.406 72.640  200.989 1.00 48.34  ? 285 THR A N   1 
ATOM   2196 C CA  . THR A 1 288 ? 123.033 72.157  202.312 1.00 48.77  ? 285 THR A CA  1 
ATOM   2197 C C   . THR A 1 288 ? 122.313 73.273  203.057 1.00 49.95  ? 285 THR A C   1 
ATOM   2198 O O   . THR A 1 288 ? 122.928 74.282  203.419 1.00 50.55  ? 285 THR A O   1 
ATOM   2199 C CB  . THR A 1 288 ? 124.248 71.676  203.096 1.00 55.45  ? 285 THR A CB  1 
ATOM   2200 O OG1 . THR A 1 288 ? 124.796 70.513  202.453 1.00 58.50  ? 285 THR A OG1 1 
ATOM   2201 C CG2 . THR A 1 288 ? 123.844 71.331  204.551 1.00 44.98  ? 285 THR A CG2 1 
ATOM   2202 N N   . ILE A 1 289 ? 121.003 73.101  203.249 1.00 49.58  ? 286 ILE A N   1 
ATOM   2203 C CA  . ILE A 1 289 ? 120.187 73.964  204.088 1.00 44.73  ? 286 ILE A CA  1 
ATOM   2204 C C   . ILE A 1 289 ? 120.183 73.366  205.474 1.00 47.57  ? 286 ILE A C   1 
ATOM   2205 O O   . ILE A 1 289 ? 120.006 72.156  205.624 1.00 51.60  ? 286 ILE A O   1 
ATOM   2206 C CB  . ILE A 1 289 ? 118.747 74.027  203.565 1.00 52.60  ? 286 ILE A CB  1 
ATOM   2207 C CG1 . ILE A 1 289 ? 118.728 74.106  202.047 1.00 55.78  ? 286 ILE A CG1 1 
ATOM   2208 C CG2 . ILE A 1 289 ? 118.024 75.210  204.166 1.00 54.04  ? 286 ILE A CG2 1 
ATOM   2209 C CD1 . ILE A 1 289 ? 117.377 73.789  201.498 1.00 54.52  ? 286 ILE A CD1 1 
ATOM   2210 N N   . ARG A 1 290 ? 120.309 74.209  206.494 1.00 51.94  ? 287 ARG A N   1 
ATOM   2211 C CA  . ARG A 1 290 ? 120.274 73.749  207.874 1.00 49.29  ? 287 ARG A CA  1 
ATOM   2212 C C   . ARG A 1 290 ? 119.483 74.717  208.732 1.00 47.62  ? 287 ARG A C   1 
ATOM   2213 O O   . ARG A 1 290 ? 119.756 75.919  208.741 1.00 47.32  ? 287 ARG A O   1 
ATOM   2214 C CB  . ARG A 1 290 ? 121.670 73.614  208.455 1.00 46.79  ? 287 ARG A CB  1 
ATOM   2215 C CG  . ARG A 1 290 ? 121.618 72.981  209.794 1.00 49.70  ? 287 ARG A CG  1 
ATOM   2216 C CD  . ARG A 1 290 ? 122.931 73.074  210.492 1.00 54.67  ? 287 ARG A CD  1 
ATOM   2217 N NE  . ARG A 1 290 ? 122.939 72.247  211.695 1.00 59.71  ? 287 ARG A NE  1 
ATOM   2218 C CZ  . ARG A 1 290 ? 122.487 72.625  212.883 1.00 51.14  ? 287 ARG A CZ  1 
ATOM   2219 N NH1 . ARG A 1 290 ? 121.940 73.813  213.068 1.00 55.62  ? 287 ARG A NH1 1 
ATOM   2220 N NH2 . ARG A 1 290 ? 122.573 71.781  213.907 1.00 51.22  ? 287 ARG A NH2 1 
ATOM   2221 N N   . GLY A 1 291 ? 118.536 74.181  209.483 1.00 48.72  ? 288 GLY A N   1 
ATOM   2222 C CA  . GLY A 1 291 ? 117.809 74.993  210.423 1.00 50.52  ? 288 GLY A CA  1 
ATOM   2223 C C   . GLY A 1 291 ? 118.632 75.265  211.667 1.00 49.86  ? 288 GLY A C   1 
ATOM   2224 O O   . GLY A 1 291 ? 119.420 74.443  212.127 1.00 50.51  ? 288 GLY A O   1 
ATOM   2225 N N   . ILE A 1 292 ? 118.442 76.445  212.223 1.00 52.12  ? 289 ILE A N   1 
ATOM   2226 C CA  . ILE A 1 292 ? 119.199 76.889  213.379 1.00 50.27  ? 289 ILE A CA  1 
ATOM   2227 C C   . ILE A 1 292 ? 118.252 77.018  214.562 1.00 54.31  ? 289 ILE A C   1 
ATOM   2228 O O   . ILE A 1 292 ? 117.225 77.697  214.466 1.00 59.69  ? 289 ILE A O   1 
ATOM   2229 C CB  . ILE A 1 292 ? 119.899 78.218  213.093 1.00 44.26  ? 289 ILE A CB  1 
ATOM   2230 C CG1 . ILE A 1 292 ? 120.806 78.031  211.884 1.00 48.81  ? 289 ILE A CG1 1 
ATOM   2231 C CG2 . ILE A 1 292 ? 120.636 78.651  214.314 1.00 53.75  ? 289 ILE A CG2 1 
ATOM   2232 C CD1 . ILE A 1 292 ? 121.867 76.986  212.057 1.00 46.45  ? 289 ILE A CD1 1 
ATOM   2233 N N   . PHE A 1 293 ? 118.599 76.388  215.687 1.00 54.95  ? 290 PHE A N   1 
ATOM   2234 C CA  . PHE A 1 293 ? 117.800 76.528  216.900 1.00 51.48  ? 290 PHE A CA  1 
ATOM   2235 C C   . PHE A 1 293 ? 118.831 76.583  218.031 1.00 55.20  ? 290 PHE A C   1 
ATOM   2236 O O   . PHE A 1 293 ? 119.079 75.616  218.759 1.00 53.81  ? 290 PHE A O   1 
ATOM   2237 C CB  . PHE A 1 293 ? 116.796 75.386  217.047 1.00 45.33  ? 290 PHE A CB  1 
ATOM   2238 C CG  . PHE A 1 293 ? 115.714 75.652  218.054 1.00 57.01  ? 290 PHE A CG  1 
ATOM   2239 C CD1 . PHE A 1 293 ? 114.698 76.554  217.780 1.00 56.96  ? 290 PHE A CD1 1 
ATOM   2240 C CD2 . PHE A 1 293 ? 115.725 75.020  219.306 1.00 57.19  ? 290 PHE A CD2 1 
ATOM   2241 C CE1 . PHE A 1 293 ? 113.695 76.800  218.730 1.00 58.47  ? 290 PHE A CE1 1 
ATOM   2242 C CE2 . PHE A 1 293 ? 114.737 75.269  220.242 1.00 49.51  ? 290 PHE A CE2 1 
ATOM   2243 C CZ  . PHE A 1 293 ? 113.724 76.153  219.958 1.00 48.09  ? 290 PHE A CZ  1 
ATOM   2244 N N   . SER A 1 294 ? 119.396 77.775  218.224 1.00 55.33  ? 291 SER A N   1 
ATOM   2245 C CA  . SER A 1 294 ? 120.661 77.909  218.927 1.00 51.78  ? 291 SER A CA  1 
ATOM   2246 C C   . SER A 1 294 ? 120.614 77.399  220.351 1.00 53.43  ? 291 SER A C   1 
ATOM   2247 O O   . SER A 1 294 ? 121.679 77.223  220.943 1.00 60.56  ? 291 SER A O   1 
ATOM   2248 C CB  . SER A 1 294 ? 121.096 79.370  218.928 1.00 52.61  ? 291 SER A CB  1 
ATOM   2249 O OG  . SER A 1 294 ? 120.049 80.162  219.449 1.00 59.91  ? 291 SER A OG  1 
ATOM   2250 N N   . LEU A 1 295 ? 119.430 77.127  220.908 1.00 53.89  ? 292 LEU A N   1 
ATOM   2251 C CA  . LEU A 1 295 ? 119.369 76.531  222.239 1.00 50.86  ? 292 LEU A CA  1 
ATOM   2252 C C   . LEU A 1 295 ? 120.276 75.311  222.345 1.00 55.59  ? 292 LEU A C   1 
ATOM   2253 O O   . LEU A 1 295 ? 120.886 75.082  223.397 1.00 49.42  ? 292 LEU A O   1 
ATOM   2254 C CB  . LEU A 1 295 ? 117.937 76.136  222.585 1.00 48.13  ? 292 LEU A CB  1 
ATOM   2255 C CG  . LEU A 1 295 ? 116.946 77.217  222.986 1.00 49.65  ? 292 LEU A CG  1 
ATOM   2256 C CD1 . LEU A 1 295 ? 115.805 76.575  223.759 1.00 51.69  ? 292 LEU A CD1 1 
ATOM   2257 C CD2 . LEU A 1 295 ? 117.619 78.323  223.777 1.00 44.35  ? 292 LEU A CD2 1 
ATOM   2258 N N   . GLU A 1 296 ? 120.455 74.568  221.271 1.00 53.89  ? 293 GLU A N   1 
ATOM   2259 C CA  . GLU A 1 296 ? 121.261 73.359  221.326 1.00 50.66  ? 293 GLU A CA  1 
ATOM   2260 C C   . GLU A 1 296 ? 122.665 73.650  221.745 1.00 54.70  ? 293 GLU A C   1 
ATOM   2261 O O   . GLU A 1 296 ? 123.349 72.782  222.258 1.00 58.98  ? 293 GLU A O   1 
ATOM   2262 C CB  . GLU A 1 296 ? 121.293 72.718  219.949 1.00 45.15  ? 293 GLU A CB  1 
ATOM   2263 C CG  . GLU A 1 296 ? 121.818 73.618  218.851 1.00 51.98  ? 293 GLU A CG  1 
ATOM   2264 C CD  . GLU A 1 296 ? 122.122 72.855  217.582 1.00 56.49  ? 293 GLU A CD  1 
ATOM   2265 O OE1 . GLU A 1 296 ? 122.527 71.681  217.678 1.00 54.60  ? 293 GLU A OE1 1 
ATOM   2266 O OE2 . GLU A 1 296 ? 121.951 73.429  216.489 1.00 53.98  ? 293 GLU A OE2 1 
ATOM   2267 N N   . TRP A 1 297 ? 123.105 74.867  221.547 1.00 53.33  ? 294 TRP A N   1 
ATOM   2268 C CA  . TRP A 1 297 ? 124.472 75.272  221.822 1.00 53.06  ? 294 TRP A CA  1 
ATOM   2269 C C   . TRP A 1 297 ? 124.637 75.908  223.191 1.00 59.94  ? 294 TRP A C   1 
ATOM   2270 O O   . TRP A 1 297 ? 125.725 76.418  223.488 1.00 62.90  ? 294 TRP A O   1 
ATOM   2271 C CB  . TRP A 1 297 ? 124.951 76.264  220.769 1.00 56.25  ? 294 TRP A CB  1 
ATOM   2272 C CG  . TRP A 1 297 ? 124.961 75.732  219.400 1.00 56.37  ? 294 TRP A CG  1 
ATOM   2273 C CD1 . TRP A 1 297 ? 125.262 74.458  219.009 1.00 55.69  ? 294 TRP A CD1 1 
ATOM   2274 C CD2 . TRP A 1 297 ? 124.649 76.455  218.214 1.00 58.86  ? 294 TRP A CD2 1 
ATOM   2275 N NE1 . TRP A 1 297 ? 125.156 74.340  217.647 1.00 49.76  ? 294 TRP A NE1 1 
ATOM   2276 C CE2 . TRP A 1 297 ? 124.779 75.555  217.132 1.00 58.71  ? 294 TRP A CE2 1 
ATOM   2277 C CE3 . TRP A 1 297 ? 124.267 77.778  217.955 1.00 58.28  ? 294 TRP A CE3 1 
ATOM   2278 C CZ2 . TRP A 1 297 ? 124.537 75.938  215.812 1.00 54.25  ? 294 TRP A CZ2 1 
ATOM   2279 C CZ3 . TRP A 1 297 ? 124.030 78.154  216.636 1.00 58.52  ? 294 TRP A CZ3 1 
ATOM   2280 C CH2 . TRP A 1 297 ? 124.168 77.238  215.587 1.00 51.63  ? 294 TRP A CH2 1 
ATOM   2281 N N   . PHE A 1 298 ? 123.582 75.933  224.016 1.00 60.45  ? 295 PHE A N   1 
ATOM   2282 C CA  . PHE A 1 298 ? 123.649 76.541  225.349 1.00 50.51  ? 295 PHE A CA  1 
ATOM   2283 C C   . PHE A 1 298 ? 124.314 75.549  226.296 1.00 51.71  ? 295 PHE A C   1 
ATOM   2284 O O   . PHE A 1 298 ? 123.665 74.812  227.041 1.00 53.76  ? 295 PHE A O   1 
ATOM   2285 C CB  . PHE A 1 298 ? 122.270 76.940  225.849 1.00 49.08  ? 295 PHE A CB  1 
ATOM   2286 C CG  . PHE A 1 298 ? 121.718 78.174  225.201 1.00 51.55  ? 295 PHE A CG  1 
ATOM   2287 C CD1 . PHE A 1 298 ? 122.214 78.630  223.985 1.00 58.32  ? 295 PHE A CD1 1 
ATOM   2288 C CD2 . PHE A 1 298 ? 120.739 78.909  225.834 1.00 43.99  ? 295 PHE A CD2 1 
ATOM   2289 C CE1 . PHE A 1 298 ? 121.710 79.775  223.395 1.00 56.24  ? 295 PHE A CE1 1 
ATOM   2290 C CE2 . PHE A 1 298 ? 120.244 80.048  225.263 1.00 48.70  ? 295 PHE A CE2 1 
ATOM   2291 C CZ  . PHE A 1 298 ? 120.722 80.487  224.041 1.00 54.28  ? 295 PHE A CZ  1 
ATOM   2292 N N   . THR A 1 299 ? 125.640 75.482  226.207 1.00 56.54  ? 296 THR A N   1 
ATOM   2293 C CA  . THR A 1 299 ? 126.464 74.686  227.105 1.00 60.37  ? 296 THR A CA  1 
ATOM   2294 C C   . THR A 1 299 ? 127.623 75.521  227.639 1.00 60.39  ? 296 THR A C   1 
ATOM   2295 O O   . THR A 1 299 ? 127.943 76.598  227.121 1.00 57.85  ? 296 THR A O   1 
ATOM   2296 C CB  . THR A 1 299 ? 126.998 73.423  226.420 1.00 58.31  ? 296 THR A CB  1 
ATOM   2297 O OG1 . THR A 1 299 ? 127.997 73.777  225.453 1.00 60.47  ? 296 THR A OG1 1 
ATOM   2298 C CG2 . THR A 1 299 ? 125.875 72.678  225.757 1.00 54.99  ? 296 THR A CG2 1 
ATOM   2299 N N   . GLU A 1 300 ? 128.248 75.013  228.702 1.00 61.00  ? 297 GLU A N   1 
ATOM   2300 C CA  . GLU A 1 300 ? 129.262 75.799  229.398 1.00 67.80  ? 297 GLU A CA  1 
ATOM   2301 C C   . GLU A 1 300 ? 130.455 76.095  228.497 1.00 66.17  ? 297 GLU A C   1 
ATOM   2302 O O   . GLU A 1 300 ? 130.865 77.252  228.354 1.00 65.31  ? 297 GLU A O   1 
ATOM   2303 C CB  . GLU A 1 300 ? 129.697 75.062  230.660 1.00 68.54  ? 297 GLU A CB  1 
ATOM   2304 C CG  . GLU A 1 300 ? 128.510 74.729  231.546 1.00 78.44  ? 297 GLU A CG  1 
ATOM   2305 C CD  . GLU A 1 300 ? 128.871 73.973  232.810 1.00 80.37  ? 297 GLU A CD  1 
ATOM   2306 O OE1 . GLU A 1 300 ? 130.075 73.677  233.006 1.00 83.78  ? 297 GLU A OE1 1 
ATOM   2307 O OE2 . GLU A 1 300 ? 127.928 73.643  233.575 1.00 67.75  ? 297 GLU A OE2 1 
ATOM   2308 N N   . GLN A 1 301 ? 131.000 75.067  227.842 1.00 63.28  ? 298 GLN A N   1 
ATOM   2309 C CA  . GLN A 1 301 ? 132.150 75.296  226.973 1.00 68.97  ? 298 GLN A CA  1 
ATOM   2310 C C   . GLN A 1 301 ? 131.825 76.332  225.909 1.00 67.49  ? 298 GLN A C   1 
ATOM   2311 O O   . GLN A 1 301 ? 132.630 77.237  225.647 1.00 67.43  ? 298 GLN A O   1 
ATOM   2312 C CB  . GLN A 1 301 ? 132.620 73.991  226.322 1.00 71.20  ? 298 GLN A CB  1 
ATOM   2313 C CG  . GLN A 1 301 ? 132.829 72.829  227.283 1.00 69.45  ? 298 GLN A CG  1 
ATOM   2314 C CD  . GLN A 1 301 ? 131.536 72.078  227.569 1.00 74.92  ? 298 GLN A CD  1 
ATOM   2315 O OE1 . GLN A 1 301 ? 130.582 72.634  228.134 1.00 68.27  ? 298 GLN A OE1 1 
ATOM   2316 N NE2 . GLN A 1 301 ? 131.490 70.810  227.159 1.00 78.29  ? 298 GLN A NE2 1 
ATOM   2317 N N   . ASN A 1 302 ? 130.634 76.232  225.309 1.00 65.30  ? 299 ASN A N   1 
ATOM   2318 C CA  . ASN A 1 302 ? 130.245 77.194  224.284 1.00 63.10  ? 299 ASN A CA  1 
ATOM   2319 C C   . ASN A 1 302 ? 130.210 78.611  224.845 1.00 64.20  ? 299 ASN A C   1 
ATOM   2320 O O   . ASN A 1 302 ? 130.726 79.544  224.217 1.00 61.40  ? 299 ASN A O   1 
ATOM   2321 C CB  . ASN A 1 302 ? 128.890 76.810  223.678 1.00 59.72  ? 299 ASN A CB  1 
ATOM   2322 C CG  . ASN A 1 302 ? 129.000 75.700  222.637 1.00 63.43  ? 299 ASN A CG  1 
ATOM   2323 O OD1 . ASN A 1 302 ? 130.017 75.572  221.949 1.00 64.86  ? 299 ASN A OD1 1 
ATOM   2324 N ND2 . ASN A 1 302 ? 127.941 74.907  222.502 1.00 64.14  ? 299 ASN A ND2 1 
ATOM   2325 N N   . TRP A 1 303 ? 129.647 78.791  226.043 1.00 62.42  ? 300 TRP A N   1 
ATOM   2326 C CA  . TRP A 1 303 ? 129.623 80.130  226.615 1.00 63.00  ? 300 TRP A CA  1 
ATOM   2327 C C   . TRP A 1 303 ? 131.040 80.648  226.857 1.00 67.01  ? 300 TRP A C   1 
ATOM   2328 O O   . TRP A 1 303 ? 131.336 81.827  226.618 1.00 66.48  ? 300 TRP A O   1 
ATOM   2329 C CB  . TRP A 1 303 ? 128.809 80.139  227.900 1.00 57.71  ? 300 TRP A CB  1 
ATOM   2330 C CG  . TRP A 1 303 ? 127.341 79.993  227.718 1.00 51.92  ? 300 TRP A CG  1 
ATOM   2331 C CD1 . TRP A 1 303 ? 126.559 79.016  228.234 1.00 52.97  ? 300 TRP A CD1 1 
ATOM   2332 C CD2 . TRP A 1 303 ? 126.465 80.867  226.988 1.00 60.64  ? 300 TRP A CD2 1 
ATOM   2333 N NE1 . TRP A 1 303 ? 125.249 79.218  227.888 1.00 57.55  ? 300 TRP A NE1 1 
ATOM   2334 C CE2 . TRP A 1 303 ? 125.161 80.342  227.111 1.00 59.46  ? 300 TRP A CE2 1 
ATOM   2335 C CE3 . TRP A 1 303 ? 126.657 82.032  226.228 1.00 59.79  ? 300 TRP A CE3 1 
ATOM   2336 C CZ2 . TRP A 1 303 ? 124.048 80.935  226.497 1.00 57.21  ? 300 TRP A CZ2 1 
ATOM   2337 C CZ3 . TRP A 1 303 ? 125.553 82.624  225.624 1.00 57.71  ? 300 TRP A CZ3 1 
ATOM   2338 C CH2 . TRP A 1 303 ? 124.264 82.070  225.761 1.00 56.93  ? 300 TRP A CH2 1 
ATOM   2339 N N   . SER A 1 304 ? 131.929 79.781  227.335 1.00 62.67  ? 301 SER A N   1 
ATOM   2340 C CA  . SER A 1 304 ? 133.328 80.156  227.477 1.00 63.10  ? 301 SER A CA  1 
ATOM   2341 C C   . SER A 1 304 ? 133.903 80.661  226.157 1.00 70.05  ? 301 SER A C   1 
ATOM   2342 O O   . SER A 1 304 ? 134.359 81.807  226.052 1.00 70.33  ? 301 SER A O   1 
ATOM   2343 C CB  . SER A 1 304 ? 134.110 78.949  227.969 1.00 64.45  ? 301 SER A CB  1 
ATOM   2344 O OG  . SER A 1 304 ? 133.553 78.474  229.174 1.00 78.92  ? 301 SER A OG  1 
ATOM   2345 N N   . ALA A 1 305 ? 133.836 79.829  225.119 1.00 65.75  ? 302 ALA A N   1 
ATOM   2346 C CA  . ALA A 1 305 ? 134.396 80.222  223.839 1.00 65.76  ? 302 ALA A CA  1 
ATOM   2347 C C   . ALA A 1 305 ? 133.795 81.535  223.364 1.00 72.45  ? 302 ALA A C   1 
ATOM   2348 O O   . ALA A 1 305 ? 134.519 82.419  222.888 1.00 75.95  ? 302 ALA A O   1 
ATOM   2349 C CB  . ALA A 1 305 ? 134.167 79.118  222.813 1.00 68.31  ? 302 ALA A CB  1 
ATOM   2350 N N   . LEU A 1 306 ? 132.478 81.702  223.534 1.00 71.37  ? 303 LEU A N   1 
ATOM   2351 C CA  . LEU A 1 306 ? 131.811 82.907  223.044 1.00 69.11  ? 303 LEU A CA  1 
ATOM   2352 C C   . LEU A 1 306 ? 132.359 84.154  223.715 1.00 72.76  ? 303 LEU A C   1 
ATOM   2353 O O   . LEU A 1 306 ? 132.459 85.212  223.079 1.00 73.57  ? 303 LEU A O   1 
ATOM   2354 C CB  . LEU A 1 306 ? 130.295 82.800  223.247 1.00 62.12  ? 303 LEU A CB  1 
ATOM   2355 C CG  . LEU A 1 306 ? 129.433 83.935  222.684 1.00 59.92  ? 303 LEU A CG  1 
ATOM   2356 C CD1 . LEU A 1 306 ? 129.803 84.235  221.258 1.00 59.89  ? 303 LEU A CD1 1 
ATOM   2357 C CD2 . LEU A 1 306 ? 127.965 83.589  222.765 1.00 57.98  ? 303 LEU A CD2 1 
ATOM   2358 N N   . HIS A 1 307 ? 132.800 84.026  224.942 1.00 72.66  ? 304 HIS A N   1 
ATOM   2359 C CA  . HIS A 1 307 ? 133.381 85.175  225.580 1.00 75.61  ? 304 HIS A CA  1 
ATOM   2360 C C   . HIS A 1 307 ? 134.773 85.444  225.048 1.00 77.13  ? 304 HIS A C   1 
ATOM   2361 O O   . HIS A 1 307 ? 135.061 86.538  224.590 1.00 74.55  ? 304 HIS A O   1 
ATOM   2362 C CB  . HIS A 1 307 ? 133.397 84.976  227.084 1.00 71.92  ? 304 HIS A CB  1 
ATOM   2363 C CG  . HIS A 1 307 ? 132.065 85.201  227.725 1.00 78.72  ? 304 HIS A CG  1 
ATOM   2364 N ND1 . HIS A 1 307 ? 131.048 84.275  227.668 1.00 75.28  ? 304 HIS A ND1 1 
ATOM   2365 C CD2 . HIS A 1 307 ? 131.578 86.254  228.421 1.00 77.02  ? 304 HIS A CD2 1 
ATOM   2366 C CE1 . HIS A 1 307 ? 129.994 84.743  228.311 1.00 74.06  ? 304 HIS A CE1 1 
ATOM   2367 N NE2 . HIS A 1 307 ? 130.289 85.943  228.776 1.00 77.44  ? 304 HIS A NE2 1 
ATOM   2368 N N   . GLU A 1 308 ? 135.639 84.451  225.099 1.00 71.77  ? 305 GLU A N   1 
ATOM   2369 C CA  . GLU A 1 308 ? 137.017 84.673  224.674 1.00 72.07  ? 305 GLU A CA  1 
ATOM   2370 C C   . GLU A 1 308 ? 137.069 85.090  223.213 1.00 75.59  ? 305 GLU A C   1 
ATOM   2371 O O   . GLU A 1 308 ? 137.515 86.195  222.881 1.00 78.31  ? 305 GLU A O   1 
ATOM   2372 C CB  . GLU A 1 308 ? 137.867 83.431  224.926 1.00 73.38  ? 305 GLU A CB  1 
ATOM   2373 C CG  . GLU A 1 308 ? 137.190 82.137  224.559 1.00 81.96  ? 305 GLU A CG  1 
ATOM   2374 C CD  . GLU A 1 308 ? 138.173 80.989  224.420 1.00 87.50  ? 305 GLU A CD  1 
ATOM   2375 O OE1 . GLU A 1 308 ? 138.936 80.758  225.388 1.00 84.34  ? 305 GLU A OE1 1 
ATOM   2376 O OE2 . GLU A 1 308 ? 138.192 80.338  223.341 1.00 85.75  ? 305 GLU A OE2 1 
ATOM   2377 N N   . GLU A 1 309 ? 136.606 84.211  222.325 1.00 75.31  ? 306 GLU A N   1 
ATOM   2378 C CA  . GLU A 1 309 ? 136.676 84.465  220.891 1.00 78.64  ? 306 GLU A CA  1 
ATOM   2379 C C   . GLU A 1 309 ? 135.990 85.780  220.534 1.00 79.88  ? 306 GLU A C   1 
ATOM   2380 O O   . GLU A 1 309 ? 136.618 86.706  220.006 1.00 79.57  ? 306 GLU A O   1 
ATOM   2381 C CB  . GLU A 1 309 ? 136.037 83.297  220.139 1.00 75.79  ? 306 GLU A CB  1 
ATOM   2382 C CG  . GLU A 1 309 ? 136.708 81.946  220.389 1.00 77.00  ? 306 GLU A CG  1 
ATOM   2383 C CD  . GLU A 1 309 ? 136.560 80.992  219.206 1.00 80.86  ? 306 GLU A CD  1 
ATOM   2384 O OE1 . GLU A 1 309 ? 136.387 81.481  218.065 1.00 69.90  ? 306 GLU A OE1 1 
ATOM   2385 O OE2 . GLU A 1 309 ? 136.609 79.757  219.418 1.00 83.14  ? 306 GLU A OE2 1 
ATOM   2386 N N   . LEU A 1 310 ? 134.689 85.874  220.811 1.00 81.19  ? 307 LEU A N   1 
ATOM   2387 C CA  . LEU A 1 310 ? 133.904 87.027  220.374 1.00 83.65  ? 307 LEU A CA  1 
ATOM   2388 C C   . LEU A 1 310 ? 134.105 88.255  221.263 1.00 85.14  ? 307 LEU A C   1 
ATOM   2389 O O   . LEU A 1 310 ? 134.263 89.373  220.755 1.00 79.21  ? 307 LEU A O   1 
ATOM   2390 C CB  . LEU A 1 310 ? 132.423 86.664  220.312 1.00 77.14  ? 307 LEU A CB  1 
ATOM   2391 C CG  . LEU A 1 310 ? 131.810 87.328  219.089 1.00 75.82  ? 307 LEU A CG  1 
ATOM   2392 C CD1 . LEU A 1 310 ? 132.512 86.795  217.857 1.00 66.18  ? 307 LEU A CD1 1 
ATOM   2393 C CD2 . LEU A 1 310 ? 130.313 87.081  219.039 1.00 75.19  ? 307 LEU A CD2 1 
ATOM   2394 N N   . GLY A 1 311 ? 134.066 88.070  222.591 1.00 83.44  ? 308 GLY A N   1 
ATOM   2395 C CA  . GLY A 1 311 ? 134.121 89.214  223.494 1.00 81.03  ? 308 GLY A CA  1 
ATOM   2396 C C   . GLY A 1 311 ? 135.335 90.103  223.280 1.00 83.69  ? 308 GLY A C   1 
ATOM   2397 O O   . GLY A 1 311 ? 135.234 91.334  223.339 1.00 80.17  ? 308 GLY A O   1 
ATOM   2398 N N   . GLY A 1 312 ? 136.498 89.495  223.028 1.00 85.34  ? 309 GLY A N   1 
ATOM   2399 C CA  . GLY A 1 312 ? 137.681 90.288  222.731 1.00 81.70  ? 309 GLY A CA  1 
ATOM   2400 C C   . GLY A 1 312 ? 137.440 91.249  221.592 1.00 78.48  ? 309 GLY A C   1 
ATOM   2401 O O   . GLY A 1 312 ? 137.611 92.460  221.735 1.00 76.96  ? 309 GLY A O   1 
ATOM   2402 N N   . LEU A 1 313 ? 136.979 90.718  220.462 1.00 77.93  ? 310 LEU A N   1 
ATOM   2403 C CA  . LEU A 1 313 ? 136.735 91.538  219.284 1.00 78.93  ? 310 LEU A CA  1 
ATOM   2404 C C   . LEU A 1 313 ? 135.801 92.692  219.595 1.00 78.61  ? 310 LEU A C   1 
ATOM   2405 O O   . LEU A 1 313 ? 135.986 93.801  219.085 1.00 79.61  ? 310 LEU A O   1 
ATOM   2406 C CB  . LEU A 1 313 ? 136.146 90.681  218.171 1.00 79.82  ? 310 LEU A CB  1 
ATOM   2407 C CG  . LEU A 1 313 ? 137.005 89.473  217.832 1.00 75.78  ? 310 LEU A CG  1 
ATOM   2408 C CD1 . LEU A 1 313 ? 136.239 88.585  216.906 1.00 70.07  ? 310 LEU A CD1 1 
ATOM   2409 C CD2 . LEU A 1 313 ? 138.325 89.908  217.226 1.00 76.34  ? 310 LEU A CD2 1 
ATOM   2410 N N   . VAL A 1 314 ? 134.771 92.446  220.405 1.00 82.60  ? 311 VAL A N   1 
ATOM   2411 C CA  . VAL A 1 314 ? 133.833 93.515  220.731 1.00 85.35  ? 311 VAL A CA  1 
ATOM   2412 C C   . VAL A 1 314 ? 134.523 94.605  221.546 1.00 85.83  ? 311 VAL A C   1 
ATOM   2413 O O   . VAL A 1 314 ? 134.439 95.793  221.206 1.00 89.34  ? 311 VAL A O   1 
ATOM   2414 C CB  . VAL A 1 314 ? 132.585 92.955  221.440 1.00 81.54  ? 311 VAL A CB  1 
ATOM   2415 C CG1 . VAL A 1 314 ? 131.684 94.083  221.907 1.00 76.66  ? 311 VAL A CG1 1 
ATOM   2416 C CG2 . VAL A 1 314 ? 131.806 92.053  220.487 1.00 72.69  ? 311 VAL A CG2 1 
ATOM   2417 N N   . ARG A 1 315 ? 135.237 94.232  222.616 1.00 84.38  ? 312 ARG A N   1 
ATOM   2418 C CA  . ARG A 1 315 ? 135.863 95.283  223.420 1.00 87.02  ? 312 ARG A CA  1 
ATOM   2419 C C   . ARG A 1 315 ? 137.001 95.990  222.689 1.00 81.42  ? 312 ARG A C   1 
ATOM   2420 O O   . ARG A 1 315 ? 137.271 97.158  222.971 1.00 82.56  ? 312 ARG A O   1 
ATOM   2421 C CB  . ARG A 1 315 ? 136.355 94.751  224.774 1.00 77.02  ? 312 ARG A CB  1 
ATOM   2422 C CG  . ARG A 1 315 ? 135.247 94.589  225.810 1.00 77.61  ? 312 ARG A CG  1 
ATOM   2423 C CD  . ARG A 1 315 ? 135.800 94.615  227.229 1.00 84.89  ? 312 ARG A CD  1 
ATOM   2424 N NE  . ARG A 1 315 ? 136.370 93.362  227.709 1.00 84.57  ? 312 ARG A NE  1 
ATOM   2425 C CZ  . ARG A 1 315 ? 135.856 92.660  228.712 1.00 86.46  ? 312 ARG A CZ  1 
ATOM   2426 N NH1 . ARG A 1 315 ? 134.770 93.067  229.352 1.00 86.51  ? 312 ARG A NH1 1 
ATOM   2427 N NH2 . ARG A 1 315 ? 136.458 91.537  229.100 1.00 85.85  ? 312 ARG A NH2 1 
ATOM   2428 N N   . ARG A 1 316 ? 137.606 95.359  221.694 1.00 81.21  ? 313 ARG A N   1 
ATOM   2429 C CA  . ARG A 1 316 ? 138.705 95.968  220.962 1.00 84.44  ? 313 ARG A CA  1 
ATOM   2430 C C   . ARG A 1 316 ? 138.235 96.670  219.701 1.00 88.89  ? 313 ARG A C   1 
ATOM   2431 O O   . ARG A 1 316 ? 139.053 96.961  218.825 1.00 92.11  ? 313 ARG A O   1 
ATOM   2432 C CB  . ARG A 1 316 ? 139.778 94.922  220.648 1.00 83.12  ? 313 ARG A CB  1 
ATOM   2433 C CG  . ARG A 1 316 ? 140.355 94.277  221.905 1.00 87.80  ? 313 ARG A CG  1 
ATOM   2434 C CD  . ARG A 1 316 ? 141.567 93.386  221.658 1.00 87.00  ? 313 ARG A CD  1 
ATOM   2435 N NE  . ARG A 1 316 ? 141.169 92.070  221.164 1.00 92.81  ? 313 ARG A NE  1 
ATOM   2436 C CZ  . ARG A 1 316 ? 141.013 91.006  221.950 1.00 90.73  ? 313 ARG A CZ  1 
ATOM   2437 N NH1 . ARG A 1 316 ? 141.173 91.084  223.263 1.00 77.95  ? 313 ARG A NH1 1 
ATOM   2438 N NH2 . ARG A 1 316 ? 140.677 89.837  221.409 1.00 85.05  ? 313 ARG A NH2 1 
ATOM   2439 N N   . GLN A 1 317 ? 136.934 96.962  219.605 1.00 87.77  ? 314 GLN A N   1 
ATOM   2440 C CA  . GLN A 1 317 ? 136.313 97.672  218.487 1.00 83.88  ? 314 GLN A CA  1 
ATOM   2441 C C   . GLN A 1 317 ? 136.441 96.938  217.161 1.00 82.52  ? 314 GLN A C   1 
ATOM   2442 O O   . GLN A 1 317 ? 136.150 97.519  216.110 1.00 84.10  ? 314 GLN A O   1 
ATOM   2443 C CB  . GLN A 1 317 ? 136.882 99.095  218.332 1.00 82.50  ? 314 GLN A CB  1 
ATOM   2444 C CG  . GLN A 1 317 ? 136.739 99.971  219.559 1.00 86.77  ? 314 GLN A CG  1 
ATOM   2445 C CD  . GLN A 1 317 ? 135.287 100.274 219.881 1.00 84.11  ? 314 GLN A CD  1 
ATOM   2446 O OE1 . GLN A 1 317 ? 134.624 101.033 219.167 1.00 81.39  ? 314 GLN A OE1 1 
ATOM   2447 N NE2 . GLN A 1 317 ? 134.772 99.648  220.936 1.00 82.04  ? 314 GLN A NE2 1 
ATOM   2448 N N   . GLU A 1 318 ? 136.817 95.675  217.159 1.00 82.49  ? 315 GLU A N   1 
ATOM   2449 C CA  . GLU A 1 318 ? 136.910 94.934  215.909 1.00 83.53  ? 315 GLU A CA  1 
ATOM   2450 C C   . GLU A 1 318 ? 135.568 94.384  215.469 1.00 83.20  ? 315 GLU A C   1 
ATOM   2451 O O   . GLU A 1 318 ? 135.412 93.982  214.323 1.00 77.93  ? 315 GLU A O   1 
ATOM   2452 C CB  . GLU A 1 318 ? 137.918 93.808  216.072 1.00 85.59  ? 315 GLU A CB  1 
ATOM   2453 C CG  . GLU A 1 318 ? 138.750 93.915  217.339 1.00 90.06  ? 315 GLU A CG  1 
ATOM   2454 C CD  . GLU A 1 318 ? 140.021 93.092  217.278 1.00 97.01  ? 315 GLU A CD  1 
ATOM   2455 O OE1 . GLU A 1 318 ? 140.699 92.956  218.318 1.00 94.73  ? 315 GLU A OE1 1 
ATOM   2456 O OE2 . GLU A 1 318 ? 140.345 92.579  216.189 1.00 100.00 ? 315 GLU A OE2 1 
ATOM   2457 N N   . LEU A 1 319 ? 134.600 94.376  216.379 1.00 86.96  ? 316 LEU A N   1 
ATOM   2458 C CA  . LEU A 1 319 ? 133.269 93.893  216.064 1.00 76.31  ? 316 LEU A CA  1 
ATOM   2459 C C   . LEU A 1 319 ? 132.246 94.779  216.730 1.00 71.34  ? 316 LEU A C   1 
ATOM   2460 O O   . LEU A 1 319 ? 132.266 94.943  217.935 1.00 77.16  ? 316 LEU A O   1 
ATOM   2461 C CB  . LEU A 1 319 ? 133.103 92.469  216.555 1.00 77.76  ? 316 LEU A CB  1 
ATOM   2462 C CG  . LEU A 1 319 ? 133.374 91.342  215.567 1.00 77.59  ? 316 LEU A CG  1 
ATOM   2463 C CD1 . LEU A 1 319 ? 132.670 90.084  216.039 1.00 72.32  ? 316 LEU A CD1 1 
ATOM   2464 C CD2 . LEU A 1 319 ? 132.891 91.739  214.185 1.00 71.15  ? 316 LEU A CD2 1 
ATOM   2465 N N   . VAL A 1 320 ? 131.355 95.360  215.951 1.00 65.19  ? 317 VAL A N   1 
ATOM   2466 C CA  . VAL A 1 320 ? 130.312 96.215  216.493 1.00 66.75  ? 317 VAL A CA  1 
ATOM   2467 C C   . VAL A 1 320 ? 129.171 95.333  216.966 1.00 72.89  ? 317 VAL A C   1 
ATOM   2468 O O   . VAL A 1 320 ? 128.789 94.376  216.285 1.00 70.15  ? 317 VAL A O   1 
ATOM   2469 C CB  . VAL A 1 320 ? 129.825 97.231  215.455 1.00 71.77  ? 317 VAL A CB  1 
ATOM   2470 C CG1 . VAL A 1 320 ? 128.635 98.013  215.999 1.00 73.67  ? 317 VAL A CG1 1 
ATOM   2471 C CG2 . VAL A 1 320 ? 130.959 98.147  215.073 1.00 78.74  ? 317 VAL A CG2 1 
ATOM   2472 N N   . ALA A 1 321 ? 128.684 95.607  218.177 1.00 82.57  ? 318 ALA A N   1 
ATOM   2473 C CA  . ALA A 1 321 ? 127.587 94.877  218.816 1.00 77.19  ? 318 ALA A CA  1 
ATOM   2474 C C   . ALA A 1 321 ? 126.736 95.949  219.484 1.00 82.13  ? 318 ALA A C   1 
ATOM   2475 O O   . ALA A 1 321 ? 126.965 96.288  220.650 1.00 88.35  ? 318 ALA A O   1 
ATOM   2476 C CB  . ALA A 1 321 ? 128.092 93.851  219.825 1.00 73.47  ? 318 ALA A CB  1 
ATOM   2477 N N   . HIS A 1 322 ? 125.787 96.500  218.739 1.00 76.61  ? 319 HIS A N   1 
ATOM   2478 C CA  . HIS A 1 322 ? 125.020 97.617  219.263 1.00 82.87  ? 319 HIS A CA  1 
ATOM   2479 C C   . HIS A 1 322 ? 123.837 97.127  220.088 1.00 85.65  ? 319 HIS A C   1 
ATOM   2480 O O   . HIS A 1 322 ? 123.386 95.985  219.961 1.00 82.13  ? 319 HIS A O   1 
ATOM   2481 C CB  . HIS A 1 322 ? 124.535 98.517  218.140 1.00 85.08  ? 319 HIS A CB  1 
ATOM   2482 C CG  . HIS A 1 322 ? 125.564 99.500  217.696 1.00 97.38  ? 319 HIS A CG  1 
ATOM   2483 N ND1 . HIS A 1 322 ? 125.490 100.173 216.494 1.00 101.57 ? 319 HIS A ND1 1 
ATOM   2484 C CD2 . HIS A 1 322 ? 126.715 99.903  218.285 1.00 95.64  ? 319 HIS A CD2 1 
ATOM   2485 C CE1 . HIS A 1 322 ? 126.545 100.958 216.368 1.00 98.51  ? 319 HIS A CE1 1 
ATOM   2486 N NE2 . HIS A 1 322 ? 127.306 100.810 217.440 1.00 99.89  ? 319 HIS A NE2 1 
ATOM   2487 N N   . GLU A 1 323 ? 123.374 97.995  220.987 1.00 81.90  ? 320 GLU A N   1 
ATOM   2488 C CA  . GLU A 1 323 ? 122.211 97.687  221.804 1.00 76.12  ? 320 GLU A CA  1 
ATOM   2489 C C   . GLU A 1 323 ? 121.461 98.965  222.138 1.00 75.14  ? 320 GLU A C   1 
ATOM   2490 O O   . GLU A 1 323 ? 122.054 100.033 222.298 1.00 81.39  ? 320 GLU A O   1 
ATOM   2491 C CB  . GLU A 1 323 ? 122.588 96.930  223.087 1.00 74.23  ? 320 GLU A CB  1 
ATOM   2492 C CG  . GLU A 1 323 ? 123.408 97.701  224.119 1.00 75.10  ? 320 GLU A CG  1 
ATOM   2493 C CD  . GLU A 1 323 ? 123.742 96.866  225.360 1.00 75.76  ? 320 GLU A CD  1 
ATOM   2494 O OE1 . GLU A 1 323 ? 123.283 95.697  225.474 1.00 68.74  ? 320 GLU A OE1 1 
ATOM   2495 O OE2 . GLU A 1 323 ? 124.490 97.382  226.217 1.00 83.32  ? 320 GLU A OE2 1 
ATOM   2496 N N   . THR A 1 324 ? 120.144 98.838  222.223 1.00 74.19  ? 321 THR A N   1 
ATOM   2497 C CA  . THR A 1 324 ? 119.237 99.944  222.508 1.00 73.05  ? 321 THR A CA  1 
ATOM   2498 C C   . THR A 1 324 ? 118.456 99.563  223.769 1.00 74.54  ? 321 THR A C   1 
ATOM   2499 O O   . THR A 1 324 ? 117.517 98.761  223.703 1.00 74.31  ? 321 THR A O   1 
ATOM   2500 C CB  . THR A 1 324 ? 118.337 100.229 221.304 1.00 70.16  ? 321 THR A CB  1 
ATOM   2501 O OG1 . THR A 1 324 ? 119.156 100.629 220.198 1.00 81.33  ? 321 THR A OG1 1 
ATOM   2502 C CG2 . THR A 1 324 ? 117.346 101.325 221.595 1.00 63.42  ? 321 THR A CG2 1 
ATOM   2503 N N   . VAL A 1 325 ? 118.872 100.111 224.914 1.00 70.34  ? 322 VAL A N   1 
ATOM   2504 C CA  . VAL A 1 325 ? 118.320 99.774  226.219 1.00 62.82  ? 322 VAL A CA  1 
ATOM   2505 C C   . VAL A 1 325 ? 117.368 100.884 226.655 1.00 67.02  ? 322 VAL A C   1 
ATOM   2506 O O   . VAL A 1 325 ? 117.786 101.907 227.203 1.00 70.42  ? 322 VAL A O   1 
ATOM   2507 C CB  . VAL A 1 325 ? 119.419 99.558  227.258 1.00 61.01  ? 322 VAL A CB  1 
ATOM   2508 C CG1 . VAL A 1 325 ? 118.795 99.020  228.558 1.00 59.83  ? 322 VAL A CG1 1 
ATOM   2509 C CG2 . VAL A 1 325 ? 120.486 98.636  226.699 1.00 59.82  ? 322 VAL A CG2 1 
ATOM   2510 N N   . GLN A 1 326 ? 116.082 100.688 226.419 1.00 66.13  ? 323 GLN A N   1 
ATOM   2511 C CA  . GLN A 1 326 ? 115.078 101.470 227.117 1.00 68.31  ? 323 GLN A CA  1 
ATOM   2512 C C   . GLN A 1 326 ? 115.116 101.147 228.615 1.00 66.89  ? 323 GLN A C   1 
ATOM   2513 O O   . GLN A 1 326 ? 115.753 100.182 229.052 1.00 62.72  ? 323 GLN A O   1 
ATOM   2514 C CB  . GLN A 1 326 ? 113.692 101.201 226.528 1.00 65.42  ? 323 GLN A CB  1 
ATOM   2515 C CG  . GLN A 1 326 ? 113.221 102.253 225.520 1.00 75.10  ? 323 GLN A CG  1 
ATOM   2516 C CD  . GLN A 1 326 ? 112.475 103.427 226.176 1.00 89.58  ? 323 GLN A CD  1 
ATOM   2517 O OE1 . GLN A 1 326 ? 112.498 103.599 227.408 1.00 78.02  ? 323 GLN A OE1 1 
ATOM   2518 N NE2 . GLN A 1 326 ? 111.802 104.238 225.347 1.00 88.93  ? 323 GLN A NE2 1 
ATOM   2519 N N   . ASP A 1 327 ? 114.383 101.936 229.381 1.00 69.63  ? 324 ASP A N   1 
ATOM   2520 C CA  . ASP A 1 327 ? 114.340 101.730 230.806 1.00 66.85  ? 324 ASP A CA  1 
ATOM   2521 C C   . ASP A 1 327 ? 112.927 101.791 231.307 1.00 64.58  ? 324 ASP A C   1 
ATOM   2522 O O   . ASP A 1 327 ? 112.095 102.484 230.742 1.00 69.03  ? 324 ASP A O   1 
ATOM   2523 C CB  . ASP A 1 327 ? 115.152 102.800 231.516 1.00 72.16  ? 324 ASP A CB  1 
ATOM   2524 C CG  . ASP A 1 327 ? 116.601 102.415 231.699 1.00 83.84  ? 324 ASP A CG  1 
ATOM   2525 O OD1 . ASP A 1 327 ? 117.046 101.422 231.099 1.00 83.63  ? 324 ASP A OD1 1 
ATOM   2526 O OD2 . ASP A 1 327 ? 117.307 103.118 232.445 1.00 97.86  ? 324 ASP A OD2 1 
ATOM   2527 N N   . GLY A 1 328 ? 112.648 101.068 232.365 1.00 60.45  ? 325 GLY A N   1 
ATOM   2528 C CA  . GLY A 1 328 ? 111.333 101.037 232.987 1.00 60.64  ? 325 GLY A CA  1 
ATOM   2529 C C   . GLY A 1 328 ? 110.483 99.823  232.680 1.00 60.62  ? 325 GLY A C   1 
ATOM   2530 O O   . GLY A 1 328 ? 110.203 99.562  231.511 1.00 63.97  ? 325 GLY A O   1 
ATOM   2531 N N   . PHE A 1 329 ? 110.039 99.079  233.699 1.00 58.92  ? 326 PHE A N   1 
ATOM   2532 C CA  . PHE A 1 329 ? 109.226 97.895  233.430 1.00 55.49  ? 326 PHE A CA  1 
ATOM   2533 C C   . PHE A 1 329 ? 107.950 98.247  232.671 1.00 59.35  ? 326 PHE A C   1 
ATOM   2534 O O   . PHE A 1 329 ? 107.521 97.501  231.779 1.00 54.20  ? 326 PHE A O   1 
ATOM   2535 C CB  . PHE A 1 329 ? 108.896 97.187  234.735 1.00 53.21  ? 326 PHE A CB  1 
ATOM   2536 C CG  . PHE A 1 329 ? 108.104 95.927  234.560 1.00 54.47  ? 326 PHE A CG  1 
ATOM   2537 C CD1 . PHE A 1 329 ? 108.733 94.726  234.260 1.00 52.69  ? 326 PHE A CD1 1 
ATOM   2538 C CD2 . PHE A 1 329 ? 106.725 95.939  234.714 1.00 55.61  ? 326 PHE A CD2 1 
ATOM   2539 C CE1 . PHE A 1 329 ? 108.000 93.559  234.101 1.00 48.10  ? 326 PHE A CE1 1 
ATOM   2540 C CE2 . PHE A 1 329 ? 105.984 94.776  234.556 1.00 54.44  ? 326 PHE A CE2 1 
ATOM   2541 C CZ  . PHE A 1 329 ? 106.626 93.583  234.251 1.00 51.08  ? 326 PHE A CZ  1 
ATOM   2542 N N   . GLU A 1 330 ? 107.369 99.414  232.960 1.00 65.52  ? 327 GLU A N   1 
ATOM   2543 C CA  . GLU A 1 330 ? 106.120 99.814  232.318 1.00 61.04  ? 327 GLU A CA  1 
ATOM   2544 C C   . GLU A 1 330 ? 106.245 99.923  230.802 1.00 54.22  ? 327 GLU A C   1 
ATOM   2545 O O   . GLU A 1 330 ? 105.236 99.786  230.110 1.00 58.47  ? 327 GLU A O   1 
ATOM   2546 C CB  . GLU A 1 330 ? 105.643 101.156 232.885 1.00 59.60  ? 327 GLU A CB  1 
ATOM   2547 C CG  . GLU A 1 330 ? 106.693 102.260 232.771 1.00 61.55  ? 327 GLU A CG  1 
ATOM   2548 C CD  . GLU A 1 330 ? 107.384 102.581 234.078 1.00 69.70  ? 327 GLU A CD  1 
ATOM   2549 O OE1 . GLU A 1 330 ? 107.076 101.927 235.099 1.00 78.79  ? 327 GLU A OE1 1 
ATOM   2550 O OE2 . GLU A 1 330 ? 108.270 103.463 234.071 1.00 72.99  ? 327 GLU A OE2 1 
ATOM   2551 N N   . HIS A 1 331 ? 107.447 100.142 230.266 1.00 52.72  ? 328 HIS A N   1 
ATOM   2552 C CA  . HIS A 1 331 ? 107.619 100.438 228.847 1.00 59.35  ? 328 HIS A CA  1 
ATOM   2553 C C   . HIS A 1 331 ? 108.018 99.223  228.016 1.00 60.55  ? 328 HIS A C   1 
ATOM   2554 O O   . HIS A 1 331 ? 108.388 99.384  226.848 1.00 57.19  ? 328 HIS A O   1 
ATOM   2555 C CB  . HIS A 1 331 ? 108.632 101.574 228.646 1.00 58.13  ? 328 HIS A CB  1 
ATOM   2556 C CG  . HIS A 1 331 ? 108.177 102.889 229.202 1.00 61.69  ? 328 HIS A CG  1 
ATOM   2557 N ND1 . HIS A 1 331 ? 108.700 103.441 230.351 1.00 64.46  ? 328 HIS A ND1 1 
ATOM   2558 C CD2 . HIS A 1 331 ? 107.230 103.756 228.768 1.00 58.86  ? 328 HIS A CD2 1 
ATOM   2559 C CE1 . HIS A 1 331 ? 108.100 104.592 230.600 1.00 62.53  ? 328 HIS A CE1 1 
ATOM   2560 N NE2 . HIS A 1 331 ? 107.206 104.808 229.652 1.00 59.87  ? 328 HIS A NE2 1 
ATOM   2561 N N   . ILE A 1 332 ? 107.941 98.016  228.588 1.00 63.22  ? 329 ILE A N   1 
ATOM   2562 C CA  . ILE A 1 332 ? 108.370 96.820  227.857 1.00 60.96  ? 329 ILE A CA  1 
ATOM   2563 C C   . ILE A 1 332 ? 107.591 96.612  226.564 1.00 58.84  ? 329 ILE A C   1 
ATOM   2564 O O   . ILE A 1 332 ? 108.230 96.414  225.511 1.00 58.51  ? 329 ILE A O   1 
ATOM   2565 C CB  . ILE A 1 332 ? 108.317 95.590  228.777 1.00 52.22  ? 329 ILE A CB  1 
ATOM   2566 C CG1 . ILE A 1 332 ? 109.423 95.659  229.799 1.00 51.84  ? 329 ILE A CG1 1 
ATOM   2567 C CG2 . ILE A 1 332 ? 108.531 94.338  227.972 1.00 52.74  ? 329 ILE A CG2 1 
ATOM   2568 C CD1 . ILE A 1 332 ? 109.403 94.482  230.680 1.00 54.98  ? 329 ILE A CD1 1 
ATOM   2569 N N   . PRO A 1 333 ? 106.253 96.637  226.540 1.00 55.44  ? 330 PRO A N   1 
ATOM   2570 C CA  . PRO A 1 333 ? 105.570 96.431  225.254 1.00 54.01  ? 330 PRO A CA  1 
ATOM   2571 C C   . PRO A 1 333 ? 105.783 97.581  224.310 1.00 56.70  ? 330 PRO A C   1 
ATOM   2572 O O   . PRO A 1 333 ? 105.889 97.356  223.096 1.00 55.66  ? 330 PRO A O   1 
ATOM   2573 C CB  . PRO A 1 333 ? 104.094 96.265  225.637 1.00 47.01  ? 330 PRO A CB  1 
ATOM   2574 C CG  . PRO A 1 333 ? 104.138 95.901  227.075 1.00 56.73  ? 330 PRO A CG  1 
ATOM   2575 C CD  . PRO A 1 333 ? 105.285 96.703  227.639 1.00 52.63  ? 330 PRO A CD  1 
ATOM   2576 N N   . ALA A 1 334 ? 105.891 98.802  224.831 1.00 59.22  ? 331 ALA A N   1 
ATOM   2577 C CA  . ALA A 1 334 ? 106.311 99.910  223.985 1.00 54.50  ? 331 ALA A CA  1 
ATOM   2578 C C   . ALA A 1 334 ? 107.608 99.553  223.273 1.00 58.37  ? 331 ALA A C   1 
ATOM   2579 O O   . ALA A 1 334 ? 107.685 99.592  222.039 1.00 60.63  ? 331 ALA A O   1 
ATOM   2580 C CB  . ALA A 1 334 ? 106.468 101.189 224.817 1.00 52.03  ? 331 ALA A CB  1 
ATOM   2581 N N   . ALA A 1 335 ? 108.610 99.107  224.038 1.00 55.63  ? 332 ALA A N   1 
ATOM   2582 C CA  . ALA A 1 335 ? 109.898 98.773  223.446 1.00 55.30  ? 332 ALA A CA  1 
ATOM   2583 C C   . ALA A 1 335 ? 109.770 97.665  222.417 1.00 57.51  ? 332 ALA A C   1 
ATOM   2584 O O   . ALA A 1 335 ? 110.424 97.704  221.374 1.00 62.63  ? 332 ALA A O   1 
ATOM   2585 C CB  . ALA A 1 335 ? 110.883 98.364  224.532 1.00 52.25  ? 332 ALA A CB  1 
ATOM   2586 N N   . TYR A 1 336 ? 108.926 96.673  222.689 1.00 58.38  ? 333 TYR A N   1 
ATOM   2587 C CA  . TYR A 1 336 ? 108.723 95.573  221.749 1.00 59.33  ? 333 TYR A CA  1 
ATOM   2588 C C   . TYR A 1 336 ? 108.134 96.066  220.427 1.00 67.61  ? 333 TYR A C   1 
ATOM   2589 O O   . TYR A 1 336 ? 108.530 95.592  219.346 1.00 64.49  ? 333 TYR A O   1 
ATOM   2590 C CB  . TYR A 1 336 ? 107.842 94.515  222.417 1.00 53.73  ? 333 TYR A CB  1 
ATOM   2591 C CG  . TYR A 1 336 ? 107.326 93.346  221.596 1.00 52.68  ? 333 TYR A CG  1 
ATOM   2592 C CD1 . TYR A 1 336 ? 108.176 92.354  221.121 1.00 54.74  ? 333 TYR A CD1 1 
ATOM   2593 C CD2 . TYR A 1 336 ? 105.958 93.178  221.405 1.00 52.73  ? 333 TYR A CD2 1 
ATOM   2594 C CE1 . TYR A 1 336 ? 107.674 91.260  220.406 1.00 56.49  ? 333 TYR A CE1 1 
ATOM   2595 C CE2 . TYR A 1 336 ? 105.449 92.099  220.702 1.00 50.40  ? 333 TYR A CE2 1 
ATOM   2596 C CZ  . TYR A 1 336 ? 106.303 91.143  220.207 1.00 55.18  ? 333 TYR A CZ  1 
ATOM   2597 O OH  . TYR A 1 336 ? 105.768 90.075  219.516 1.00 58.19  ? 333 TYR A OH  1 
ATOM   2598 N N   . GLN A 1 337 ? 107.194 97.026  220.490 1.00 64.81  ? 334 GLN A N   1 
ATOM   2599 C CA  . GLN A 1 337 ? 106.505 97.478  219.281 1.00 59.38  ? 334 GLN A CA  1 
ATOM   2600 C C   . GLN A 1 337 ? 107.462 98.099  218.278 1.00 62.89  ? 334 GLN A C   1 
ATOM   2601 O O   . GLN A 1 337 ? 107.197 98.067  217.073 1.00 67.44  ? 334 GLN A O   1 
ATOM   2602 C CB  . GLN A 1 337 ? 105.420 98.484  219.639 1.00 55.23  ? 334 GLN A CB  1 
ATOM   2603 C CG  . GLN A 1 337 ? 104.515 98.828  218.495 1.00 51.77  ? 334 GLN A CG  1 
ATOM   2604 C CD  . GLN A 1 337 ? 103.534 97.726  218.186 1.00 57.84  ? 334 GLN A CD  1 
ATOM   2605 O OE1 . GLN A 1 337 ? 102.597 97.489  218.947 1.00 62.25  ? 334 GLN A OE1 1 
ATOM   2606 N NE2 . GLN A 1 337 ? 103.733 97.047  217.062 1.00 65.37  ? 334 GLN A NE2 1 
ATOM   2607 N N   . THR A 1 338 ? 108.579 98.653  218.755 1.00 62.75  ? 335 THR A N   1 
ATOM   2608 C CA  . THR A 1 338 ? 109.531 99.322  217.877 1.00 63.57  ? 335 THR A CA  1 
ATOM   2609 C C   . THR A 1 338 ? 110.161 98.359  216.884 1.00 66.35  ? 335 THR A C   1 
ATOM   2610 O O   . THR A 1 338 ? 110.625 98.780  215.819 1.00 68.00  ? 335 THR A O   1 
ATOM   2611 C CB  . THR A 1 338 ? 110.622 99.970  218.715 1.00 66.22  ? 335 THR A CB  1 
ATOM   2612 O OG1 . THR A 1 338 ? 111.611 98.986  219.037 1.00 66.73  ? 335 THR A OG1 1 
ATOM   2613 C CG2 . THR A 1 338 ? 110.025 100.493 220.017 1.00 63.53  ? 335 THR A CG2 1 
ATOM   2614 N N   . LEU A 1 339 ? 110.220 97.075  217.231 1.00 65.88  ? 336 LEU A N   1 
ATOM   2615 C CA  . LEU A 1 339 ? 110.792 96.086  216.330 1.00 62.62  ? 336 LEU A CA  1 
ATOM   2616 C C   . LEU A 1 339 ? 110.020 95.993  215.025 1.00 63.43  ? 336 LEU A C   1 
ATOM   2617 O O   . LEU A 1 339 ? 110.589 95.623  213.997 1.00 73.02  ? 336 LEU A O   1 
ATOM   2618 C CB  . LEU A 1 339 ? 110.854 94.728  217.014 1.00 64.29  ? 336 LEU A CB  1 
ATOM   2619 C CG  . LEU A 1 339 ? 111.645 94.732  218.315 1.00 59.06  ? 336 LEU A CG  1 
ATOM   2620 C CD1 . LEU A 1 339 ? 111.840 93.312  218.784 1.00 61.84  ? 336 LEU A CD1 1 
ATOM   2621 C CD2 . LEU A 1 339 ? 112.971 95.429  218.148 1.00 61.72  ? 336 LEU A CD2 1 
ATOM   2622 N N   . PHE A 1 340 ? 108.722 96.255  215.042 1.00 66.77  ? 337 PHE A N   1 
ATOM   2623 C CA  . PHE A 1 340 ? 107.955 96.196  213.809 1.00 67.97  ? 337 PHE A CA  1 
ATOM   2624 C C   . PHE A 1 340 ? 107.746 97.560  213.171 1.00 75.61  ? 337 PHE A C   1 
ATOM   2625 O O   . PHE A 1 340 ? 107.287 97.620  212.026 1.00 78.39  ? 337 PHE A O   1 
ATOM   2626 C CB  . PHE A 1 340 ? 106.620 95.509  214.085 1.00 65.20  ? 337 PHE A CB  1 
ATOM   2627 C CG  . PHE A 1 340 ? 106.780 94.264  214.889 1.00 65.25  ? 337 PHE A CG  1 
ATOM   2628 C CD1 . PHE A 1 340 ? 107.104 93.072  214.273 1.00 68.39  ? 337 PHE A CD1 1 
ATOM   2629 C CD2 . PHE A 1 340 ? 106.665 94.282  216.251 1.00 63.26  ? 337 PHE A CD2 1 
ATOM   2630 C CE1 . PHE A 1 340 ? 107.291 91.917  215.005 1.00 65.57  ? 337 PHE A CE1 1 
ATOM   2631 C CE2 . PHE A 1 340 ? 106.849 93.124  216.979 1.00 64.82  ? 337 PHE A CE2 1 
ATOM   2632 C CZ  . PHE A 1 340 ? 107.159 91.942  216.354 1.00 58.07  ? 337 PHE A CZ  1 
ATOM   2633 N N   . SER A 1 341 ? 108.119 98.637  213.868 1.00 79.88  ? 338 SER A N   1 
ATOM   2634 C CA  . SER A 1 341 ? 108.053 99.991  213.330 1.00 76.55  ? 338 SER A CA  1 
ATOM   2635 C C   . SER A 1 341 ? 109.139 100.229 212.297 1.00 84.53  ? 338 SER A C   1 
ATOM   2636 O O   . SER A 1 341 ? 110.303 99.864  212.490 1.00 79.39  ? 338 SER A O   1 
ATOM   2637 C CB  . SER A 1 341 ? 108.199 101.012 214.445 1.00 77.60  ? 338 SER A CB  1 
ATOM   2638 O OG  . SER A 1 341 ? 107.293 100.716 215.491 1.00 84.60  ? 338 SER A OG  1 
ATOM   2639 N N   . ALA A 1 342 ? 108.758 100.924 211.230 1.00 96.22  ? 339 ALA A N   1 
ATOM   2640 C CA  . ALA A 1 342 ? 109.642 101.235 210.115 1.00 96.67  ? 339 ALA A CA  1 
ATOM   2641 C C   . ALA A 1 342 ? 110.711 102.279 210.447 1.00 97.48  ? 339 ALA A C   1 
ATOM   2642 O O   . ALA A 1 342 ? 111.644 102.443 209.655 1.00 103.25 ? 339 ALA A O   1 
ATOM   2643 C CB  . ALA A 1 342 ? 108.804 101.677 208.909 1.00 90.42  ? 339 ALA A CB  1 
ATOM   2644 N N   . SER A 1 343 ? 110.631 102.956 211.590 1.00 94.67  ? 340 SER A N   1 
ATOM   2645 C CA  . SER A 1 343 ? 111.652 103.936 211.951 1.00 100.87 ? 340 SER A CA  1 
ATOM   2646 C C   . SER A 1 343 ? 113.045 103.309 211.994 1.00 104.82 ? 340 SER A C   1 
ATOM   2647 O O   . SER A 1 343 ? 113.205 102.104 212.212 1.00 108.12 ? 340 SER A O   1 
ATOM   2648 C CB  . SER A 1 343 ? 111.346 104.563 213.314 1.00 100.87 ? 340 SER A CB  1 
ATOM   2649 O OG  . SER A 1 343 ? 110.059 105.153 213.349 1.00 105.17 ? 340 SER A OG  1 
ATOM   2650 N N   . GLU A 1 344 ? 114.064 104.154 211.782 1.00 106.85 ? 341 GLU A N   1 
ATOM   2651 C CA  . GLU A 1 344 ? 115.456 103.723 211.733 1.00 107.58 ? 341 GLU A CA  1 
ATOM   2652 C C   . GLU A 1 344 ? 116.117 103.838 213.085 1.00 110.62 ? 341 GLU A C   1 
ATOM   2653 O O   . GLU A 1 344 ? 117.337 104.061 213.159 1.00 113.62 ? 341 GLU A O   1 
ATOM   2654 C CB  . GLU A 1 344 ? 116.243 104.600 210.754 1.00 102.39 ? 341 GLU A CB  1 
ATOM   2655 C CG  . GLU A 1 344 ? 115.802 104.583 209.323 1.00 105.78 ? 341 GLU A CG  1 
ATOM   2656 C CD  . GLU A 1 344 ? 114.822 105.696 209.006 1.00 106.59 ? 341 GLU A CD  1 
ATOM   2657 O OE1 . GLU A 1 344 ? 113.922 105.951 209.833 1.00 99.92  ? 341 GLU A OE1 1 
ATOM   2658 O OE2 . GLU A 1 344 ? 114.971 106.332 207.939 1.00 109.54 ? 341 GLU A OE2 1 
ATOM   2659 N N   . SER A 1 345 ? 115.349 103.640 214.155 1.00 108.40 ? 342 SER A N   1 
ATOM   2660 C CA  . SER A 1 345 ? 115.768 103.969 215.509 1.00 108.05 ? 342 SER A CA  1 
ATOM   2661 C C   . SER A 1 345 ? 116.473 102.833 216.235 1.00 104.69 ? 342 SER A C   1 
ATOM   2662 O O   . SER A 1 345 ? 117.006 103.055 217.326 1.00 98.99  ? 342 SER A O   1 
ATOM   2663 C CB  . SER A 1 345 ? 114.556 104.423 216.324 1.00 110.52 ? 342 SER A CB  1 
ATOM   2664 O OG  . SER A 1 345 ? 113.772 105.343 215.581 1.00 116.13 ? 342 SER A OG  1 
ATOM   2665 N N   . ASN A 1 346 ? 116.504 101.634 215.672 1.00 107.83 ? 343 ASN A N   1 
ATOM   2666 C CA  . ASN A 1 346 ? 117.094 100.496 216.356 1.00 101.17 ? 343 ASN A CA  1 
ATOM   2667 C C   . ASN A 1 346 ? 118.491 100.249 215.816 1.00 102.59 ? 343 ASN A C   1 
ATOM   2668 O O   . ASN A 1 346 ? 118.715 100.265 214.597 1.00 105.45 ? 343 ASN A O   1 
ATOM   2669 C CB  . ASN A 1 346 ? 116.247 99.237  216.177 1.00 103.96 ? 343 ASN A CB  1 
ATOM   2670 C CG  . ASN A 1 346 ? 114.994 99.238  217.045 1.00 103.22 ? 343 ASN A CG  1 
ATOM   2671 O OD1 . ASN A 1 346 ? 115.035 99.599  218.228 1.00 96.55  ? 343 ASN A OD1 1 
ATOM   2672 N ND2 . ASN A 1 346 ? 113.868 98.826  216.454 1.00 94.75  ? 343 ASN A ND2 1 
ATOM   2673 N N   . ARG A 1 347 ? 119.430 100.059 216.727 1.00 98.63  ? 344 ARG A N   1 
ATOM   2674 C CA  . ARG A 1 347 ? 120.753 99.576  216.384 1.00 100.38 ? 344 ARG A CA  1 
ATOM   2675 C C   . ARG A 1 347 ? 120.995 98.393  217.306 1.00 99.39  ? 344 ARG A C   1 
ATOM   2676 O O   . ARG A 1 347 ? 120.834 98.505  218.528 1.00 94.44  ? 344 ARG A O   1 
ATOM   2677 C CB  . ARG A 1 347 ? 121.836 100.667 216.525 1.00 92.26  ? 344 ARG A CB  1 
ATOM   2678 C CG  . ARG A 1 347 ? 122.167 101.091 217.943 1.00 94.35  ? 344 ARG A CG  1 
ATOM   2679 C CD  . ARG A 1 347 ? 123.253 102.146 217.974 1.00 101.37 ? 344 ARG A CD  1 
ATOM   2680 N NE  . ARG A 1 347 ? 122.690 103.488 217.903 1.00 106.98 ? 344 ARG A NE  1 
ATOM   2681 C CZ  . ARG A 1 347 ? 122.175 104.136 218.940 1.00 106.13 ? 344 ARG A CZ  1 
ATOM   2682 N NH1 . ARG A 1 347 ? 122.138 103.592 220.148 1.00 93.54  ? 344 ARG A NH1 1 
ATOM   2683 N NH2 . ARG A 1 347 ? 121.669 105.353 218.758 1.00 112.08 ? 344 ARG A NH2 1 
ATOM   2684 N N   . GLY A 1 348 ? 121.313 97.248  216.718 1.00 98.18  ? 345 GLY A N   1 
ATOM   2685 C CA  . GLY A 1 348 ? 121.537 96.118  217.576 1.00 87.36  ? 345 GLY A CA  1 
ATOM   2686 C C   . GLY A 1 348 ? 120.301 95.675  218.355 1.00 84.29  ? 345 GLY A C   1 
ATOM   2687 O O   . GLY A 1 348 ? 119.147 95.966  218.018 1.00 88.47  ? 345 GLY A O   1 
ATOM   2688 N N   . LYS A 1 349 ? 120.589 95.019  219.469 1.00 78.28  ? 346 LYS A N   1 
ATOM   2689 C CA  . LYS A 1 349 ? 119.593 94.361  220.290 1.00 72.23  ? 346 LYS A CA  1 
ATOM   2690 C C   . LYS A 1 349 ? 118.821 95.392  221.096 1.00 73.03  ? 346 LYS A C   1 
ATOM   2691 O O   . LYS A 1 349 ? 119.352 96.438  221.465 1.00 78.18  ? 346 LYS A O   1 
ATOM   2692 C CB  . LYS A 1 349 ? 120.294 93.380  221.229 1.00 69.72  ? 346 LYS A CB  1 
ATOM   2693 C CG  . LYS A 1 349 ? 119.393 92.519  222.048 1.00 70.76  ? 346 LYS A CG  1 
ATOM   2694 C CD  . LYS A 1 349 ? 119.082 91.260  221.280 1.00 70.57  ? 346 LYS A CD  1 
ATOM   2695 C CE  . LYS A 1 349 ? 117.851 90.593  221.829 1.00 66.91  ? 346 LYS A CE  1 
ATOM   2696 N NZ  . LYS A 1 349 ? 116.645 91.369  221.435 1.00 67.09  ? 346 LYS A NZ  1 
ATOM   2697 N N   . VAL A 1 350 ? 117.550 95.111  221.348 1.00 71.65  ? 347 VAL A N   1 
ATOM   2698 C CA  . VAL A 1 350 ? 116.708 95.987  222.161 1.00 70.08  ? 347 VAL A CA  1 
ATOM   2699 C C   . VAL A 1 350 ? 116.443 95.310  223.511 1.00 70.36  ? 347 VAL A C   1 
ATOM   2700 O O   . VAL A 1 350 ? 116.028 94.145  223.566 1.00 69.18  ? 347 VAL A O   1 
ATOM   2701 C CB  . VAL A 1 350 ? 115.406 96.343  221.424 1.00 66.50  ? 347 VAL A CB  1 
ATOM   2702 C CG1 . VAL A 1 350 ? 114.731 97.502  222.091 1.00 63.32  ? 347 VAL A CG1 1 
ATOM   2703 C CG2 . VAL A 1 350 ? 115.709 96.686  219.987 1.00 72.26  ? 347 VAL A CG2 1 
ATOM   2704 N N   . LEU A 1 351 ? 116.730 96.017  224.601 1.00 66.79  ? 348 LEU A N   1 
ATOM   2705 C CA  . LEU A 1 351 ? 116.498 95.504  225.944 1.00 63.88  ? 348 LEU A CA  1 
ATOM   2706 C C   . LEU A 1 351 ? 115.742 96.540  226.753 1.00 66.40  ? 348 LEU A C   1 
ATOM   2707 O O   . LEU A 1 351 ? 115.723 97.728  226.419 1.00 67.00  ? 348 LEU A O   1 
ATOM   2708 C CB  . LEU A 1 351 ? 117.792 95.165  226.686 1.00 57.42  ? 348 LEU A CB  1 
ATOM   2709 C CG  . LEU A 1 351 ? 118.737 94.227  225.963 1.00 63.95  ? 348 LEU A CG  1 
ATOM   2710 C CD1 . LEU A 1 351 ? 120.087 94.222  226.640 1.00 63.35  ? 348 LEU A CD1 1 
ATOM   2711 C CD2 . LEU A 1 351 ? 118.137 92.838  225.928 1.00 64.72  ? 348 LEU A CD2 1 
ATOM   2712 N N   . VAL A 1 352 ? 115.110 96.071  227.824 1.00 60.33  ? 349 VAL A N   1 
ATOM   2713 C CA  . VAL A 1 352 ? 114.512 96.943  228.818 1.00 57.36  ? 349 VAL A CA  1 
ATOM   2714 C C   . VAL A 1 352 ? 115.194 96.657  230.144 1.00 66.09  ? 349 VAL A C   1 
ATOM   2715 O O   . VAL A 1 352 ? 115.420 95.492  230.490 1.00 66.38  ? 349 VAL A O   1 
ATOM   2716 C CB  . VAL A 1 352 ? 112.989 96.735  228.929 1.00 57.05  ? 349 VAL A CB  1 
ATOM   2717 C CG1 . VAL A 1 352 ? 112.435 97.580  230.038 1.00 59.95  ? 349 VAL A CG1 1 
ATOM   2718 C CG2 . VAL A 1 352 ? 112.302 97.056  227.631 1.00 56.53  ? 349 VAL A CG2 1 
ATOM   2719 N N   . ARG A 1 353 ? 115.539 97.724  230.868 1.00 71.65  ? 350 ARG A N   1 
ATOM   2720 C CA  . ARG A 1 353 ? 116.074 97.667  232.227 1.00 65.93  ? 350 ARG A CA  1 
ATOM   2721 C C   . ARG A 1 353 ? 114.969 98.018  233.210 1.00 61.91  ? 350 ARG A C   1 
ATOM   2722 O O   . ARG A 1 353 ? 114.191 98.940  232.962 1.00 66.02  ? 350 ARG A O   1 
ATOM   2723 C CB  . ARG A 1 353 ? 117.241 98.640  232.391 1.00 69.60  ? 350 ARG A CB  1 
ATOM   2724 C CG  . ARG A 1 353 ? 117.888 98.647  233.747 1.00 69.90  ? 350 ARG A CG  1 
ATOM   2725 C CD  . ARG A 1 353 ? 118.968 99.709  233.842 1.00 72.51  ? 350 ARG A CD  1 
ATOM   2726 N NE  . ARG A 1 353 ? 118.410 101.055 233.966 1.00 89.45  ? 350 ARG A NE  1 
ATOM   2727 C CZ  . ARG A 1 353 ? 117.930 101.584 235.092 1.00 103.26 ? 350 ARG A CZ  1 
ATOM   2728 N NH1 . ARG A 1 353 ? 117.884 100.894 236.229 1.00 91.89  ? 350 ARG A NH1 1 
ATOM   2729 N NH2 . ARG A 1 353 ? 117.489 102.842 235.083 1.00 103.41 ? 350 ARG A NH2 1 
ATOM   2730 N N   . VAL A 1 354 ? 114.929 97.329  234.347 1.00 67.32  ? 351 VAL A N   1 
ATOM   2731 C CA  . VAL A 1 354 ? 113.777 97.472  235.254 1.00 69.14  ? 351 VAL A CA  1 
ATOM   2732 C C   . VAL A 1 354 ? 114.103 98.234  236.533 1.00 63.55  ? 351 VAL A C   1 
ATOM   2733 O O   . VAL A 1 354 ? 113.635 99.367  236.705 1.00 65.66  ? 351 VAL A O   1 
ATOM   2734 C CB  . VAL A 1 354 ? 113.188 96.096  235.617 1.00 60.65  ? 351 VAL A CB  1 
ATOM   2735 C CG1 . VAL A 1 354 ? 112.086 96.258  236.654 1.00 55.23  ? 351 VAL A CG1 1 
ATOM   2736 C CG2 . VAL A 1 354 ? 112.664 95.410  234.366 1.00 54.24  ? 351 VAL A CG2 1 
ATOM   2737 N N   . LEU B 1 1   ? 136.596 57.435  152.863 1.00 92.90  ? -2  LEU B N   1 
ATOM   2738 C CA  . LEU B 1 1   ? 137.390 56.250  153.176 1.00 100.11 ? -2  LEU B CA  1 
ATOM   2739 C C   . LEU B 1 1   ? 136.555 55.237  153.992 1.00 100.58 ? -2  LEU B C   1 
ATOM   2740 O O   . LEU B 1 1   ? 136.269 54.106  153.522 1.00 88.46  ? -2  LEU B O   1 
ATOM   2741 C CB  . LEU B 1 1   ? 138.660 56.655  153.935 1.00 97.51  ? -2  LEU B CB  1 
ATOM   2742 C CG  . LEU B 1 1   ? 139.779 57.175  153.017 1.00 90.14  ? -2  LEU B CG  1 
ATOM   2743 C CD1 . LEU B 1 1   ? 141.047 57.516  153.791 1.00 81.58  ? -2  LEU B CD1 1 
ATOM   2744 C CD2 . LEU B 1 1   ? 140.071 56.178  151.894 1.00 79.97  ? -2  LEU B CD2 1 
ATOM   2745 N N   . GLY B 1 2   ? 136.165 55.618  155.184 1.00 98.72  ? -1  GLY B N   1 
ATOM   2746 C CA  . GLY B 1 2   ? 135.280 54.791  155.988 1.00 86.59  ? -1  GLY B CA  1 
ATOM   2747 C C   . GLY B 1 2   ? 134.060 55.548  156.456 1.00 76.34  ? -1  GLY B C   1 
ATOM   2748 O O   . GLY B 1 2   ? 134.151 56.695  156.891 1.00 72.65  ? -1  GLY B O   1 
ATOM   2749 N N   . SER B 1 3   ? 132.914 54.880  156.361 1.00 73.47  ? 0   SER B N   1 
ATOM   2750 C CA  . SER B 1 3   ? 131.657 55.366  156.911 1.00 74.55  ? 0   SER B CA  1 
ATOM   2751 C C   . SER B 1 3   ? 130.879 54.139  157.376 1.00 81.14  ? 0   SER B C   1 
ATOM   2752 O O   . SER B 1 3   ? 131.304 52.993  157.171 1.00 77.05  ? 0   SER B O   1 
ATOM   2753 C CB  . SER B 1 3   ? 130.849 56.194  155.903 1.00 72.70  ? 0   SER B CB  1 
ATOM   2754 O OG  . SER B 1 3   ? 129.839 55.411  155.281 1.00 76.46  ? 0   SER B OG  1 
ATOM   2755 N N   . MET B 1 4   ? 129.717 54.386  157.971 1.00 77.87  ? 1   MET B N   1 
ATOM   2756 C CA  . MET B 1 4   ? 128.944 53.348  158.629 1.00 70.05  ? 1   MET B CA  1 
ATOM   2757 C C   . MET B 1 4   ? 127.506 53.810  158.759 1.00 73.23  ? 1   MET B C   1 
ATOM   2758 O O   . MET B 1 4   ? 127.258 54.985  159.043 1.00 76.48  ? 1   MET B O   1 
ATOM   2759 C CB  . MET B 1 4   ? 129.536 53.068  160.014 1.00 74.94  ? 1   MET B CB  1 
ATOM   2760 C CG  . MET B 1 4   ? 128.773 52.096  160.907 1.00 74.57  ? 1   MET B CG  1 
ATOM   2761 S SD  . MET B 1 4   ? 129.719 51.855  162.415 1.00 78.08  ? 1   MET B SD  1 
ATOM   2762 C CE  . MET B 1 4   ? 131.219 51.123  161.732 1.00 72.42  ? 1   MET B CE  1 
ATOM   2763 N N   . LYS B 1 5   ? 126.567 52.885  158.590 1.00 63.54  ? 2   LYS B N   1 
ATOM   2764 C CA  . LYS B 1 5   ? 125.162 53.204  158.791 1.00 67.87  ? 2   LYS B CA  1 
ATOM   2765 C C   . LYS B 1 5   ? 124.812 52.975  160.264 1.00 71.31  ? 2   LYS B C   1 
ATOM   2766 O O   . LYS B 1 5   ? 125.138 51.921  160.825 1.00 70.35  ? 2   LYS B O   1 
ATOM   2767 C CB  . LYS B 1 5   ? 124.289 52.340  157.875 1.00 75.20  ? 2   LYS B CB  1 
ATOM   2768 C CG  . LYS B 1 5   ? 124.053 52.873  156.421 1.00 86.88  ? 2   LYS B CG  1 
ATOM   2769 C CD  . LYS B 1 5   ? 123.887 54.396  156.327 1.00 89.50  ? 2   LYS B CD  1 
ATOM   2770 C CE  . LYS B 1 5   ? 123.393 54.838  154.947 1.00 91.97  ? 2   LYS B CE  1 
ATOM   2771 N NZ  . LYS B 1 5   ? 124.398 54.597  153.896 1.00 93.08  ? 2   LYS B NZ  1 
ATOM   2772 N N   . THR B 1 6   ? 124.173 53.965  160.904 1.00 73.41  ? 3   THR B N   1 
ATOM   2773 C CA  . THR B 1 6   ? 123.820 53.846  162.321 1.00 71.34  ? 3   THR B CA  1 
ATOM   2774 C C   . THR B 1 6   ? 122.425 54.423  162.539 1.00 70.23  ? 3   THR B C   1 
ATOM   2775 O O   . THR B 1 6   ? 122.109 55.508  162.041 1.00 68.26  ? 3   THR B O   1 
ATOM   2776 C CB  . THR B 1 6   ? 124.815 54.591  163.248 1.00 64.21  ? 3   THR B CB  1 
ATOM   2777 O OG1 . THR B 1 6   ? 124.643 56.008  163.121 1.00 66.10  ? 3   THR B OG1 1 
ATOM   2778 C CG2 . THR B 1 6   ? 126.255 54.272  162.869 1.00 63.31  ? 3   THR B CG2 1 
ATOM   2779 N N   . GLU B 1 7   ? 121.613 53.743  163.342 1.00 65.69  ? 4   GLU B N   1 
ATOM   2780 C CA  . GLU B 1 7   ? 120.299 54.274  163.660 1.00 64.30  ? 4   GLU B CA  1 
ATOM   2781 C C   . GLU B 1 7   ? 120.424 55.155  164.891 1.00 64.21  ? 4   GLU B C   1 
ATOM   2782 O O   . GLU B 1 7   ? 121.233 54.888  165.781 1.00 63.16  ? 4   GLU B O   1 
ATOM   2783 C CB  . GLU B 1 7   ? 119.279 53.162  163.912 1.00 66.15  ? 4   GLU B CB  1 
ATOM   2784 C CG  . GLU B 1 7   ? 118.814 52.403  162.676 1.00 68.65  ? 4   GLU B CG  1 
ATOM   2785 C CD  . GLU B 1 7   ? 117.580 51.513  162.940 1.00 83.34  ? 4   GLU B CD  1 
ATOM   2786 O OE1 . GLU B 1 7   ? 117.416 50.988  164.072 1.00 77.17  ? 4   GLU B OE1 1 
ATOM   2787 O OE2 . GLU B 1 7   ? 116.774 51.319  161.998 1.00 86.17  ? 4   GLU B OE2 1 
ATOM   2788 N N   . ARG B 1 8   ? 119.650 56.230  164.920 1.00 65.82  ? 5   ARG B N   1 
ATOM   2789 C CA  . ARG B 1 8   ? 119.631 57.117  166.068 1.00 58.96  ? 5   ARG B CA  1 
ATOM   2790 C C   . ARG B 1 8   ? 118.195 57.518  166.342 1.00 66.19  ? 5   ARG B C   1 
ATOM   2791 O O   . ARG B 1 8   ? 117.423 57.762  165.410 1.00 66.50  ? 5   ARG B O   1 
ATOM   2792 C CB  . ARG B 1 8   ? 120.461 58.383  165.850 1.00 57.68  ? 5   ARG B CB  1 
ATOM   2793 C CG  . ARG B 1 8   ? 121.930 58.165  165.587 1.00 62.21  ? 5   ARG B CG  1 
ATOM   2794 C CD  . ARG B 1 8   ? 122.621 59.502  165.598 1.00 62.06  ? 5   ARG B CD  1 
ATOM   2795 N NE  . ARG B 1 8   ? 121.832 60.511  164.903 1.00 67.13  ? 5   ARG B NE  1 
ATOM   2796 C CZ  . ARG B 1 8   ? 122.018 61.817  165.041 1.00 73.45  ? 5   ARG B CZ  1 
ATOM   2797 N NH1 . ARG B 1 8   ? 122.947 62.296  165.856 1.00 76.10  ? 5   ARG B NH1 1 
ATOM   2798 N NH2 . ARG B 1 8   ? 121.241 62.663  164.365 1.00 68.49  ? 5   ARG B NH2 1 
ATOM   2799 N N   . TRP B 1 9   ? 117.851 57.606  167.624 1.00 67.17  ? 6   TRP B N   1 
ATOM   2800 C CA  . TRP B 1 9   ? 116.598 58.210  168.047 1.00 63.86  ? 6   TRP B CA  1 
ATOM   2801 C C   . TRP B 1 9   ? 116.858 59.687  168.304 1.00 69.43  ? 6   TRP B C   1 
ATOM   2802 O O   . TRP B 1 9   ? 117.696 60.038  169.144 1.00 64.95  ? 6   TRP B O   1 
ATOM   2803 C CB  . TRP B 1 9   ? 116.061 57.533  169.297 1.00 60.77  ? 6   TRP B CB  1 
ATOM   2804 C CG  . TRP B 1 9   ? 115.473 56.176  169.102 1.00 62.18  ? 6   TRP B CG  1 
ATOM   2805 C CD1 . TRP B 1 9   ? 116.065 54.982  169.392 1.00 62.19  ? 6   TRP B CD1 1 
ATOM   2806 C CD2 . TRP B 1 9   ? 114.145 55.868  168.661 1.00 67.49  ? 6   TRP B CD2 1 
ATOM   2807 N NE1 . TRP B 1 9   ? 115.202 53.945  169.125 1.00 64.37  ? 6   TRP B NE1 1 
ATOM   2808 C CE2 . TRP B 1 9   ? 114.016 54.461  168.674 1.00 67.79  ? 6   TRP B CE2 1 
ATOM   2809 C CE3 . TRP B 1 9   ? 113.060 56.639  168.235 1.00 69.46  ? 6   TRP B CE3 1 
ATOM   2810 C CZ2 . TRP B 1 9   ? 112.847 53.812  168.277 1.00 68.85  ? 6   TRP B CZ2 1 
ATOM   2811 C CZ3 . TRP B 1 9   ? 111.899 55.991  167.839 1.00 68.48  ? 6   TRP B CZ3 1 
ATOM   2812 C CH2 . TRP B 1 9   ? 111.801 54.592  167.867 1.00 69.84  ? 6   TRP B CH2 1 
ATOM   2813 N N   . VAL B 1 10  ? 116.192 60.544  167.533 1.00 75.04  ? 7   VAL B N   1 
ATOM   2814 C CA  . VAL B 1 10  ? 116.348 61.985  167.641 1.00 72.07  ? 7   VAL B CA  1 
ATOM   2815 C C   . VAL B 1 10  ? 115.068 62.578  168.209 1.00 77.55  ? 7   VAL B C   1 
ATOM   2816 O O   . VAL B 1 10  ? 114.004 61.946  168.225 1.00 77.67  ? 7   VAL B O   1 
ATOM   2817 C CB  . VAL B 1 10  ? 116.687 62.609  166.285 1.00 70.61  ? 7   VAL B CB  1 
ATOM   2818 C CG1 . VAL B 1 10  ? 118.076 62.151  165.823 1.00 67.88  ? 7   VAL B CG1 1 
ATOM   2819 C CG2 . VAL B 1 10  ? 115.629 62.195  165.307 1.00 71.14  ? 7   VAL B CG2 1 
ATOM   2820 N N   . VAL B 1 11  ? 115.179 63.820  168.671 1.00 79.76  ? 8   VAL B N   1 
ATOM   2821 C CA  . VAL B 1 11  ? 114.076 64.518  169.327 1.00 85.79  ? 8   VAL B CA  1 
ATOM   2822 C C   . VAL B 1 11  ? 113.268 65.254  168.256 1.00 81.12  ? 8   VAL B C   1 
ATOM   2823 O O   . VAL B 1 11  ? 113.732 66.244  167.679 1.00 77.33  ? 8   VAL B O   1 
ATOM   2824 C CB  . VAL B 1 11  ? 114.588 65.474  170.419 1.00 85.89  ? 8   VAL B CB  1 
ATOM   2825 C CG1 . VAL B 1 11  ? 113.486 66.435  170.872 1.00 85.09  ? 8   VAL B CG1 1 
ATOM   2826 C CG2 . VAL B 1 11  ? 115.159 64.701  171.616 1.00 72.04  ? 8   VAL B CG2 1 
ATOM   2827 N N   . ARG B 1 12  ? 112.049 64.803  168.021 1.00 81.93  ? 9   ARG B N   1 
ATOM   2828 C CA  . ARG B 1 12  ? 111.205 65.421  167.012 1.00 82.37  ? 9   ARG B CA  1 
ATOM   2829 C C   . ARG B 1 12  ? 110.476 66.646  167.529 1.00 86.06  ? 9   ARG B C   1 
ATOM   2830 O O   . ARG B 1 12  ? 110.442 67.671  166.863 1.00 82.18  ? 9   ARG B O   1 
ATOM   2831 C CB  . ARG B 1 12  ? 110.186 64.405  166.523 1.00 80.50  ? 9   ARG B CB  1 
ATOM   2832 C CG  . ARG B 1 12  ? 109.609 64.694  165.154 1.00 84.70  ? 9   ARG B CG  1 
ATOM   2833 C CD  . ARG B 1 12  ? 108.195 64.153  165.040 1.00 82.86  ? 9   ARG B CD  1 
ATOM   2834 N NE  . ARG B 1 12  ? 108.005 62.935  165.820 1.00 77.34  ? 9   ARG B NE  1 
ATOM   2835 C CZ  . ARG B 1 12  ? 107.670 61.762  165.297 1.00 84.59  ? 9   ARG B CZ  1 
ATOM   2836 N NH1 . ARG B 1 12  ? 107.490 61.645  163.991 1.00 81.95  ? 9   ARG B NH1 1 
ATOM   2837 N NH2 . ARG B 1 12  ? 107.516 60.704  166.079 1.00 83.08  ? 9   ARG B NH2 1 
ATOM   2838 N N   . GLU B 1 13  ? 109.883 66.543  168.711 1.00 89.92  ? 10  GLU B N   1 
ATOM   2839 C CA  . GLU B 1 13  ? 109.133 67.662  169.277 1.00 92.27  ? 10  GLU B CA  1 
ATOM   2840 C C   . GLU B 1 13  ? 109.221 67.663  170.807 1.00 87.96  ? 10  GLU B C   1 
ATOM   2841 O O   . GLU B 1 13  ? 109.230 66.606  171.447 1.00 85.51  ? 10  GLU B O   1 
ATOM   2842 C CB  . GLU B 1 13  ? 107.655 67.624  168.843 1.00 93.43  ? 10  GLU B CB  1 
ATOM   2843 C CG  . GLU B 1 13  ? 106.928 68.957  169.026 1.00 92.23  ? 10  GLU B CG  1 
ATOM   2844 C CD  . GLU B 1 13  ? 105.427 68.786  169.163 1.00 93.51  ? 10  GLU B CD  1 
ATOM   2845 O OE1 . GLU B 1 13  ? 104.850 67.891  168.501 1.00 88.97  ? 10  GLU B OE1 1 
ATOM   2846 O OE2 . GLU B 1 13  ? 104.840 69.518  169.996 1.00 92.64  ? 10  GLU B OE2 1 
ATOM   2847 N N   . HIS B 1 14  ? 109.224 68.867  171.390 1.00 85.75  ? 11  HIS B N   1 
ATOM   2848 C CA  . HIS B 1 14  ? 109.238 69.042  172.839 1.00 81.52  ? 11  HIS B CA  1 
ATOM   2849 C C   . HIS B 1 14  ? 107.800 69.095  173.343 1.00 84.31  ? 11  HIS B C   1 
ATOM   2850 O O   . HIS B 1 14  ? 107.031 69.966  172.932 1.00 88.24  ? 11  HIS B O   1 
ATOM   2851 C CB  . HIS B 1 14  ? 109.965 70.328  173.233 1.00 70.72  ? 11  HIS B CB  1 
ATOM   2852 C CG  . HIS B 1 14  ? 111.430 70.317  172.935 1.00 74.68  ? 11  HIS B CG  1 
ATOM   2853 N ND1 . HIS B 1 14  ? 112.187 71.468  172.890 1.00 78.19  ? 11  HIS B ND1 1 
ATOM   2854 C CD2 . HIS B 1 14  ? 112.278 69.302  172.649 1.00 78.93  ? 11  HIS B CD2 1 
ATOM   2855 C CE1 . HIS B 1 14  ? 113.438 71.165  172.593 1.00 76.32  ? 11  HIS B CE1 1 
ATOM   2856 N NE2 . HIS B 1 14  ? 113.520 69.856  172.439 1.00 77.74  ? 11  HIS B NE2 1 
ATOM   2857 N N   . VAL B 1 15  ? 107.442 68.185  174.248 1.00 86.55  ? 12  VAL B N   1 
ATOM   2858 C CA  . VAL B 1 15  ? 106.102 68.121  174.829 1.00 83.85  ? 12  VAL B CA  1 
ATOM   2859 C C   . VAL B 1 15  ? 106.254 68.080  176.345 1.00 89.78  ? 12  VAL B C   1 
ATOM   2860 O O   . VAL B 1 15  ? 106.943 67.197  176.873 1.00 93.99  ? 12  VAL B O   1 
ATOM   2861 C CB  . VAL B 1 15  ? 105.322 66.890  174.327 1.00 84.55  ? 12  VAL B CB  1 
ATOM   2862 C CG1 . VAL B 1 15  ? 103.965 66.781  175.001 1.00 79.21  ? 12  VAL B CG1 1 
ATOM   2863 C CG2 . VAL B 1 15  ? 105.174 66.933  172.816 1.00 87.01  ? 12  VAL B CG2 1 
ATOM   2864 N N   . GLU B 1 16  ? 105.604 69.018  177.045 1.00 92.94  ? 13  GLU B N   1 
ATOM   2865 C CA  . GLU B 1 16  ? 105.702 69.080  178.501 1.00 87.40  ? 13  GLU B CA  1 
ATOM   2866 C C   . GLU B 1 16  ? 104.724 68.134  179.174 1.00 85.10  ? 13  GLU B C   1 
ATOM   2867 O O   . GLU B 1 16  ? 103.706 67.740  178.602 1.00 85.52  ? 13  GLU B O   1 
ATOM   2868 C CB  . GLU B 1 16  ? 105.497 70.496  179.037 1.00 80.69  ? 13  GLU B CB  1 
ATOM   2869 C CG  . GLU B 1 16  ? 106.625 71.419  178.656 1.00 86.59  ? 13  GLU B CG  1 
ATOM   2870 C CD  . GLU B 1 16  ? 107.617 71.553  179.806 1.00 100.36 ? 13  GLU B CD  1 
ATOM   2871 O OE1 . GLU B 1 16  ? 107.551 70.719  180.744 1.00 96.51  ? 13  GLU B OE1 1 
ATOM   2872 O OE2 . GLU B 1 16  ? 108.463 72.474  179.775 1.00 105.12 ? 13  GLU B OE2 1 
ATOM   2873 N N   . GLY B 1 17  ? 105.060 67.763  180.405 1.00 82.17  ? 14  GLY B N   1 
ATOM   2874 C CA  . GLY B 1 17  ? 104.262 66.818  181.141 1.00 75.65  ? 14  GLY B CA  1 
ATOM   2875 C C   . GLY B 1 17  ? 104.769 65.411  180.925 1.00 74.12  ? 14  GLY B C   1 
ATOM   2876 O O   . GLY B 1 17  ? 105.887 65.176  180.448 1.00 75.21  ? 14  GLY B O   1 
ATOM   2877 N N   . VAL B 1 18  ? 103.932 64.459  181.326 1.00 70.53  ? 15  VAL B N   1 
ATOM   2878 C CA  . VAL B 1 18  ? 104.176 63.036  181.104 1.00 76.30  ? 15  VAL B CA  1 
ATOM   2879 C C   . VAL B 1 18  ? 104.442 62.855  179.609 1.00 82.23  ? 15  VAL B C   1 
ATOM   2880 O O   . VAL B 1 18  ? 103.576 63.189  178.783 1.00 79.55  ? 15  VAL B O   1 
ATOM   2881 C CB  . VAL B 1 18  ? 102.992 62.189  181.606 1.00 69.52  ? 15  VAL B CB  1 
ATOM   2882 C CG1 . VAL B 1 18  ? 103.262 60.719  181.454 1.00 77.47  ? 15  VAL B CG1 1 
ATOM   2883 C CG2 . VAL B 1 18  ? 102.693 62.488  183.037 1.00 70.85  ? 15  VAL B CG2 1 
ATOM   2884 N N   . PRO B 1 19  ? 105.614 62.361  179.205 1.00 81.91  ? 16  PRO B N   1 
ATOM   2885 C CA  . PRO B 1 19  ? 105.982 62.424  177.786 1.00 81.29  ? 16  PRO B CA  1 
ATOM   2886 C C   . PRO B 1 19  ? 105.162 61.472  176.940 1.00 81.68  ? 16  PRO B C   1 
ATOM   2887 O O   . PRO B 1 19  ? 104.666 60.446  177.411 1.00 80.57  ? 16  PRO B O   1 
ATOM   2888 C CB  . PRO B 1 19  ? 107.465 62.026  177.778 1.00 82.66  ? 16  PRO B CB  1 
ATOM   2889 C CG  . PRO B 1 19  ? 107.894 62.019  179.237 1.00 84.62  ? 16  PRO B CG  1 
ATOM   2890 C CD  . PRO B 1 19  ? 106.661 61.717  180.013 1.00 80.06  ? 16  PRO B CD  1 
ATOM   2891 N N   . ASP B 1 20  ? 105.009 61.851  175.670 1.00 87.42  ? 17  ASP B N   1 
ATOM   2892 C CA  . ASP B 1 20  ? 104.470 60.980  174.628 1.00 90.89  ? 17  ASP B CA  1 
ATOM   2893 C C   . ASP B 1 20  ? 105.668 60.549  173.791 1.00 87.85  ? 17  ASP B C   1 
ATOM   2894 O O   . ASP B 1 20  ? 106.135 61.290  172.918 1.00 83.34  ? 17  ASP B O   1 
ATOM   2895 C CB  . ASP B 1 20  ? 103.412 61.704  173.799 1.00 91.00  ? 17  ASP B CB  1 
ATOM   2896 C CG  . ASP B 1 20  ? 102.743 60.804  172.773 1.00 87.14  ? 17  ASP B CG  1 
ATOM   2897 O OD1 . ASP B 1 20  ? 102.975 59.574  172.779 1.00 87.83  ? 17  ASP B OD1 1 
ATOM   2898 O OD2 . ASP B 1 20  ? 101.957 61.339  171.969 1.00 87.22  ? 17  ASP B OD2 1 
ATOM   2899 N N   . ALA B 1 21  ? 106.181 59.352  174.096 1.00 84.14  ? 18  ALA B N   1 
ATOM   2900 C CA  . ALA B 1 21  ? 107.445 58.908  173.520 1.00 82.48  ? 18  ALA B CA  1 
ATOM   2901 C C   . ALA B 1 21  ? 107.313 58.668  172.022 1.00 87.10  ? 18  ALA B C   1 
ATOM   2902 O O   . ALA B 1 21  ? 108.209 59.026  171.244 1.00 81.01  ? 18  ALA B O   1 
ATOM   2903 C CB  . ALA B 1 21  ? 107.922 57.646  174.237 1.00 75.46  ? 18  ALA B CB  1 
ATOM   2904 N N   . ALA B 1 22  ? 106.197 58.061  171.604 1.00 86.93  ? 19  ALA B N   1 
ATOM   2905 C CA  . ALA B 1 22  ? 105.981 57.805  170.190 1.00 79.98  ? 19  ALA B CA  1 
ATOM   2906 C C   . ALA B 1 22  ? 105.906 59.110  169.402 1.00 79.43  ? 19  ALA B C   1 
ATOM   2907 O O   . ALA B 1 22  ? 106.327 59.165  168.240 1.00 79.65  ? 19  ALA B O   1 
ATOM   2908 C CB  . ALA B 1 22  ? 104.706 56.975  170.031 1.00 83.56  ? 19  ALA B CB  1 
ATOM   2909 N N   . ARG B 1 23  ? 105.463 60.182  170.048 1.00 78.80  ? 20  ARG B N   1 
ATOM   2910 C CA  . ARG B 1 23  ? 105.347 61.495  169.433 1.00 81.88  ? 20  ARG B CA  1 
ATOM   2911 C C   . ARG B 1 23  ? 106.626 62.301  169.525 1.00 81.01  ? 20  ARG B C   1 
ATOM   2912 O O   . ARG B 1 23  ? 106.933 63.076  168.611 1.00 83.99  ? 20  ARG B O   1 
ATOM   2913 C CB  . ARG B 1 23  ? 104.216 62.281  170.110 1.00 93.48  ? 20  ARG B CB  1 
ATOM   2914 C CG  . ARG B 1 23  ? 104.155 63.792  169.822 1.00 92.60  ? 20  ARG B CG  1 
ATOM   2915 C CD  . ARG B 1 23  ? 103.039 64.434  170.642 1.00 86.53  ? 20  ARG B CD  1 
ATOM   2916 N NE  . ARG B 1 23  ? 102.897 65.862  170.387 1.00 85.43  ? 20  ARG B NE  1 
ATOM   2917 C CZ  . ARG B 1 23  ? 102.077 66.661  171.058 1.00 89.03  ? 20  ARG B CZ  1 
ATOM   2918 N NH1 . ARG B 1 23  ? 101.290 66.199  172.019 1.00 84.45  ? 20  ARG B NH1 1 
ATOM   2919 N NH2 . ARG B 1 23  ? 102.044 67.955  170.757 1.00 89.08  ? 20  ARG B NH2 1 
ATOM   2920 N N   . ILE B 1 24  ? 107.377 62.142  170.610 1.00 79.20  ? 21  ILE B N   1 
ATOM   2921 C CA  . ILE B 1 24  ? 108.549 62.982  170.781 1.00 81.58  ? 21  ILE B CA  1 
ATOM   2922 C C   . ILE B 1 24  ? 109.727 62.433  169.982 1.00 81.18  ? 21  ILE B C   1 
ATOM   2923 O O   . ILE B 1 24  ? 110.530 63.208  169.443 1.00 80.07  ? 21  ILE B O   1 
ATOM   2924 C CB  . ILE B 1 24  ? 108.879 63.150  172.280 1.00 81.83  ? 21  ILE B CB  1 
ATOM   2925 C CG1 . ILE B 1 24  ? 107.902 64.134  172.954 1.00 80.45  ? 21  ILE B CG1 1 
ATOM   2926 C CG2 . ILE B 1 24  ? 110.323 63.590  172.484 1.00 79.65  ? 21  ILE B CG2 1 
ATOM   2927 C CD1 . ILE B 1 24  ? 108.209 64.448  174.412 1.00 77.63  ? 21  ILE B CD1 1 
ATOM   2928 N N   . TYR B 1 25  ? 109.819 61.116  169.823 1.00 81.57  ? 22  TYR B N   1 
ATOM   2929 C CA  . TYR B 1 25  ? 111.042 60.483  169.350 1.00 80.06  ? 22  TYR B CA  1 
ATOM   2930 C C   . TYR B 1 25  ? 110.877 59.870  167.959 1.00 74.06  ? 22  TYR B C   1 
ATOM   2931 O O   . TYR B 1 25  ? 109.777 59.494  167.541 1.00 72.53  ? 22  TYR B O   1 
ATOM   2932 C CB  . TYR B 1 25  ? 111.489 59.433  170.372 1.00 76.69  ? 22  TYR B CB  1 
ATOM   2933 C CG  . TYR B 1 25  ? 111.935 60.071  171.669 1.00 69.82  ? 22  TYR B CG  1 
ATOM   2934 C CD1 . TYR B 1 25  ? 113.030 60.923  171.688 1.00 70.72  ? 22  TYR B CD1 1 
ATOM   2935 C CD2 . TYR B 1 25  ? 111.262 59.840  172.860 1.00 67.42  ? 22  TYR B CD2 1 
ATOM   2936 C CE1 . TYR B 1 25  ? 113.454 61.515  172.849 1.00 70.95  ? 22  TYR B CE1 1 
ATOM   2937 C CE2 . TYR B 1 25  ? 111.688 60.429  174.039 1.00 68.44  ? 22  TYR B CE2 1 
ATOM   2938 C CZ  . TYR B 1 25  ? 112.787 61.268  174.020 1.00 67.69  ? 22  TYR B CZ  1 
ATOM   2939 O OH  . TYR B 1 25  ? 113.240 61.872  175.160 1.00 62.32  ? 22  TYR B OH  1 
ATOM   2940 N N   . GLU B 1 26  ? 112.001 59.742  167.253 1.00 72.66  ? 23  GLU B N   1 
ATOM   2941 C CA  . GLU B 1 26  ? 111.965 59.329  165.853 1.00 76.67  ? 23  GLU B CA  1 
ATOM   2942 C C   . GLU B 1 26  ? 113.217 58.561  165.453 1.00 75.23  ? 23  GLU B C   1 
ATOM   2943 O O   . GLU B 1 26  ? 114.326 59.098  165.554 1.00 74.83  ? 23  GLU B O   1 
ATOM   2944 C CB  . GLU B 1 26  ? 111.813 60.569  164.977 1.00 76.78  ? 23  GLU B CB  1 
ATOM   2945 C CG  . GLU B 1 26  ? 111.751 60.324  163.506 1.00 78.59  ? 23  GLU B CG  1 
ATOM   2946 C CD  . GLU B 1 26  ? 111.346 61.575  162.767 1.00 79.15  ? 23  GLU B CD  1 
ATOM   2947 O OE1 . GLU B 1 26  ? 110.153 61.939  162.840 1.00 78.43  ? 23  GLU B OE1 1 
ATOM   2948 O OE2 . GLU B 1 26  ? 112.230 62.220  162.165 1.00 77.68  ? 23  GLU B OE2 1 
ATOM   2949 N N   . LYS B 1 27  ? 113.032 57.345  164.925 1.00 71.39  ? 24  LYS B N   1 
ATOM   2950 C CA  . LYS B 1 27  ? 114.158 56.530  164.475 1.00 72.62  ? 24  LYS B CA  1 
ATOM   2951 C C   . LYS B 1 27  ? 114.615 57.026  163.109 1.00 70.43  ? 24  LYS B C   1 
ATOM   2952 O O   . LYS B 1 27  ? 113.818 57.088  162.169 1.00 69.97  ? 24  LYS B O   1 
ATOM   2953 C CB  . LYS B 1 27  ? 113.785 55.044  164.418 1.00 76.01  ? 24  LYS B CB  1 
ATOM   2954 C CG  . LYS B 1 27  ? 114.995 54.107  164.198 1.00 72.86  ? 24  LYS B CG  1 
ATOM   2955 C CD  . LYS B 1 27  ? 114.695 52.628  164.479 1.00 70.69  ? 24  LYS B CD  1 
ATOM   2956 C CE  . LYS B 1 27  ? 113.809 51.984  163.412 1.00 80.48  ? 24  LYS B CE  1 
ATOM   2957 N NZ  . LYS B 1 27  ? 113.988 50.492  163.344 1.00 80.35  ? 24  LYS B NZ  1 
ATOM   2958 N N   . VAL B 1 28  ? 115.888 57.414  163.013 1.00 69.51  ? 25  VAL B N   1 
ATOM   2959 C CA  . VAL B 1 28  ? 116.492 57.860  161.764 1.00 67.63  ? 25  VAL B CA  1 
ATOM   2960 C C   . VAL B 1 28  ? 117.692 56.973  161.437 1.00 71.43  ? 25  VAL B C   1 
ATOM   2961 O O   . VAL B 1 28  ? 118.286 56.343  162.321 1.00 68.03  ? 25  VAL B O   1 
ATOM   2962 C CB  . VAL B 1 28  ? 116.911 59.346  161.828 1.00 60.92  ? 25  VAL B CB  1 
ATOM   2963 C CG1 . VAL B 1 28  ? 115.751 60.205  162.314 1.00 58.69  ? 25  VAL B CG1 1 
ATOM   2964 C CG2 . VAL B 1 28  ? 118.157 59.532  162.690 1.00 60.99  ? 25  VAL B CG2 1 
ATOM   2965 N N   . GLU B 1 29  ? 118.037 56.929  160.134 1.00 72.62  ? 26  GLU B N   1 
ATOM   2966 C CA  . GLU B 1 29  ? 119.281 56.333  159.633 1.00 68.46  ? 26  GLU B CA  1 
ATOM   2967 C C   . GLU B 1 29  ? 120.316 57.446  159.513 1.00 65.61  ? 26  GLU B C   1 
ATOM   2968 O O   . GLU B 1 29  ? 119.983 58.572  159.140 1.00 61.14  ? 26  GLU B O   1 
ATOM   2969 C CB  . GLU B 1 29  ? 119.059 55.629  158.283 1.00 64.35  ? 26  GLU B CB  1 
ATOM   2970 C CG  . GLU B 1 29  ? 120.334 55.146  157.508 1.00 81.45  ? 26  GLU B CG  1 
ATOM   2971 C CD  . GLU B 1 29  ? 120.070 54.677  156.019 1.00 100.16 ? 26  GLU B CD  1 
ATOM   2972 O OE1 . GLU B 1 29  ? 119.751 55.522  155.131 1.00 96.34  ? 26  GLU B OE1 1 
ATOM   2973 O OE2 . GLU B 1 29  ? 120.209 53.459  155.728 1.00 98.21  ? 26  GLU B OE2 1 
ATOM   2974 N N   . THR B 1 30  ? 121.548 57.166  159.930 1.00 69.95  ? 27  THR B N   1 
ATOM   2975 C CA  . THR B 1 30  ? 122.566 58.210  160.030 1.00 69.76  ? 27  THR B CA  1 
ATOM   2976 C C   . THR B 1 30  ? 123.902 57.635  159.589 1.00 70.03  ? 27  THR B C   1 
ATOM   2977 O O   . THR B 1 30  ? 124.345 56.611  160.115 1.00 68.11  ? 27  THR B O   1 
ATOM   2978 C CB  . THR B 1 30  ? 122.659 58.768  161.462 1.00 69.60  ? 27  THR B CB  1 
ATOM   2979 O OG1 . THR B 1 30  ? 121.529 59.607  161.739 1.00 70.97  ? 27  THR B OG1 1 
ATOM   2980 C CG2 . THR B 1 30  ? 123.928 59.585  161.643 1.00 63.03  ? 27  THR B CG2 1 
ATOM   2981 N N   . GLU B 1 31  ? 124.532 58.274  158.611 1.00 73.12  ? 28  GLU B N   1 
ATOM   2982 C CA  . GLU B 1 31  ? 125.812 57.811  158.093 1.00 79.89  ? 28  GLU B CA  1 
ATOM   2983 C C   . GLU B 1 31  ? 126.933 58.368  158.979 1.00 77.33  ? 28  GLU B C   1 
ATOM   2984 O O   . GLU B 1 31  ? 127.079 59.591  159.116 1.00 76.25  ? 28  GLU B O   1 
ATOM   2985 C CB  . GLU B 1 31  ? 125.948 58.210  156.619 1.00 85.53  ? 28  GLU B CB  1 
ATOM   2986 C CG  . GLU B 1 31  ? 126.903 57.347  155.786 1.00 83.91  ? 28  GLU B CG  1 
ATOM   2987 C CD  . GLU B 1 31  ? 126.769 57.619  154.295 1.00 97.57  ? 28  GLU B CD  1 
ATOM   2988 O OE1 . GLU B 1 31  ? 125.644 57.937  153.833 1.00 99.27  ? 28  GLU B OE1 1 
ATOM   2989 O OE2 . GLU B 1 31  ? 127.784 57.493  153.575 1.00 107.10 ? 28  GLU B OE2 1 
ATOM   2990 N N   . LEU B 1 32  ? 127.701 57.474  159.604 1.00 71.26  ? 29  LEU B N   1 
ATOM   2991 C CA  . LEU B 1 32  ? 128.697 57.841  160.608 1.00 74.33  ? 29  LEU B CA  1 
ATOM   2992 C C   . LEU B 1 32  ? 130.112 57.779  160.036 1.00 70.11  ? 29  LEU B C   1 
ATOM   2993 O O   . LEU B 1 32  ? 130.557 56.718  159.583 1.00 67.65  ? 29  LEU B O   1 
ATOM   2994 C CB  . LEU B 1 32  ? 128.569 56.916  161.818 1.00 72.94  ? 29  LEU B CB  1 
ATOM   2995 C CG  . LEU B 1 32  ? 129.616 57.044  162.923 1.00 64.68  ? 29  LEU B CG  1 
ATOM   2996 C CD1 . LEU B 1 32  ? 129.704 58.469  163.415 1.00 63.21  ? 29  LEU B CD1 1 
ATOM   2997 C CD2 . LEU B 1 32  ? 129.281 56.085  164.045 1.00 64.23  ? 29  LEU B CD2 1 
ATOM   2998 N N   . ASN B 1 33  ? 130.828 58.902  160.072 1.00 61.50  ? 30  ASN B N   1 
ATOM   2999 C CA  . ASN B 1 33  ? 132.207 58.887  159.599 1.00 65.78  ? 30  ASN B CA  1 
ATOM   3000 C C   . ASN B 1 33  ? 133.085 58.117  160.567 1.00 66.68  ? 30  ASN B C   1 
ATOM   3001 O O   . ASN B 1 33  ? 133.281 58.545  161.705 1.00 75.58  ? 30  ASN B O   1 
ATOM   3002 C CB  . ASN B 1 33  ? 132.751 60.303  159.437 1.00 69.84  ? 30  ASN B CB  1 
ATOM   3003 C CG  . ASN B 1 33  ? 134.239 60.316  159.072 1.00 76.56  ? 30  ASN B CG  1 
ATOM   3004 O OD1 . ASN B 1 33  ? 134.684 59.542  158.213 1.00 84.59  ? 30  ASN B OD1 1 
ATOM   3005 N ND2 . ASN B 1 33  ? 135.011 61.187  159.723 1.00 67.96  ? 30  ASN B ND2 1 
ATOM   3006 N N   . THR B 1 34  ? 133.703 57.047  160.100 1.00 63.43  ? 31  THR B N   1 
ATOM   3007 C CA  . THR B 1 34  ? 134.485 56.215  160.991 1.00 65.37  ? 31  THR B CA  1 
ATOM   3008 C C   . THR B 1 34  ? 135.979 56.504  160.905 1.00 67.62  ? 31  THR B C   1 
ATOM   3009 O O   . THR B 1 34  ? 136.777 55.772  161.494 1.00 68.36  ? 31  THR B O   1 
ATOM   3010 C CB  . THR B 1 34  ? 134.211 54.744  160.695 1.00 66.38  ? 31  THR B CB  1 
ATOM   3011 O OG1 . THR B 1 34  ? 134.655 54.424  159.373 1.00 71.85  ? 31  THR B OG1 1 
ATOM   3012 C CG2 . THR B 1 34  ? 132.733 54.491  160.774 1.00 66.17  ? 31  THR B CG2 1 
ATOM   3013 N N   . ARG B 1 35  ? 136.379 57.571  160.223 1.00 71.70  ? 32  ARG B N   1 
ATOM   3014 C CA  . ARG B 1 35  ? 137.802 57.897  160.116 1.00 74.72  ? 32  ARG B CA  1 
ATOM   3015 C C   . ARG B 1 35  ? 138.188 58.664  161.378 1.00 75.13  ? 32  ARG B C   1 
ATOM   3016 O O   . ARG B 1 35  ? 138.165 59.893  161.419 1.00 79.48  ? 32  ARG B O   1 
ATOM   3017 C CB  . ARG B 1 35  ? 138.075 58.683  158.832 1.00 73.93  ? 32  ARG B CB  1 
ATOM   3018 C CG  . ARG B 1 35  ? 138.327 57.830  157.535 1.00 80.03  ? 32  ARG B CG  1 
ATOM   3019 C CD  . ARG B 1 35  ? 139.682 57.058  157.594 1.00 90.32  ? 32  ARG B CD  1 
ATOM   3020 N NE  . ARG B 1 35  ? 140.724 57.887  158.206 1.00 98.56  ? 32  ARG B NE  1 
ATOM   3021 C CZ  . ARG B 1 35  ? 141.769 57.437  158.899 1.00 93.35  ? 32  ARG B CZ  1 
ATOM   3022 N NH1 . ARG B 1 35  ? 141.991 56.141  159.055 1.00 97.77  ? 32  ARG B NH1 1 
ATOM   3023 N NH2 . ARG B 1 35  ? 142.587 58.312  159.485 1.00 78.46  ? 32  ARG B NH2 1 
ATOM   3024 N N   . LEU B 1 36  ? 138.592 57.915  162.405 1.00 71.93  ? 33  LEU B N   1 
ATOM   3025 C CA  . LEU B 1 36  ? 138.786 58.428  163.760 1.00 61.95  ? 33  LEU B CA  1 
ATOM   3026 C C   . LEU B 1 36  ? 140.071 59.225  163.895 1.00 62.29  ? 33  LEU B C   1 
ATOM   3027 O O   . LEU B 1 36  ? 141.085 58.906  163.273 1.00 73.23  ? 33  LEU B O   1 
ATOM   3028 C CB  . LEU B 1 36  ? 138.846 57.286  164.770 1.00 62.31  ? 33  LEU B CB  1 
ATOM   3029 C CG  . LEU B 1 36  ? 137.869 56.128  164.660 1.00 63.14  ? 33  LEU B CG  1 
ATOM   3030 C CD1 . LEU B 1 36  ? 138.329 55.066  165.632 1.00 63.83  ? 33  LEU B CD1 1 
ATOM   3031 C CD2 . LEU B 1 36  ? 136.459 56.580  164.952 1.00 60.56  ? 33  LEU B CD2 1 
ATOM   3032 N N   . GLY B 1 37  ? 140.027 60.262  164.731 1.00 62.29  ? 34  GLY B N   1 
ATOM   3033 C CA  . GLY B 1 37  ? 141.241 60.963  165.089 1.00 64.27  ? 34  GLY B CA  1 
ATOM   3034 C C   . GLY B 1 37  ? 142.157 60.122  165.964 1.00 68.23  ? 34  GLY B C   1 
ATOM   3035 O O   . GLY B 1 37  ? 141.816 59.033  166.431 1.00 71.86  ? 34  GLY B O   1 
ATOM   3036 N N   . GLU B 1 38  ? 143.336 60.680  166.244 1.00 68.08  ? 35  GLU B N   1 
ATOM   3037 C CA  . GLU B 1 38  ? 144.377 59.906  166.913 1.00 75.62  ? 35  GLU B CA  1 
ATOM   3038 C C   . GLU B 1 38  ? 143.980 59.501  168.330 1.00 73.93  ? 35  GLU B C   1 
ATOM   3039 O O   . GLU B 1 38  ? 144.561 58.560  168.878 1.00 71.98  ? 35  GLU B O   1 
ATOM   3040 C CB  . GLU B 1 38  ? 145.731 60.642  166.857 1.00 72.34  ? 35  GLU B CB  1 
ATOM   3041 C CG  . GLU B 1 38  ? 146.371 60.641  165.445 1.00 66.62  ? 35  GLU B CG  1 
ATOM   3042 C CD  . GLU B 1 38  ? 145.895 61.783  164.530 1.00 74.47  ? 35  GLU B CD  1 
ATOM   3043 O OE1 . GLU B 1 38  ? 145.282 62.739  165.062 1.00 76.37  ? 35  GLU B OE1 1 
ATOM   3044 O OE2 . GLU B 1 38  ? 146.093 61.712  163.280 1.00 65.69  ? 35  GLU B OE2 1 
ATOM   3045 N N   . GLU B 1 39  ? 143.038 60.198  168.955 1.00 74.30  ? 36  GLU B N   1 
ATOM   3046 C CA  . GLU B 1 39  ? 142.611 59.801  170.287 1.00 73.51  ? 36  GLU B CA  1 
ATOM   3047 C C   . GLU B 1 39  ? 141.103 59.538  170.378 1.00 75.03  ? 36  GLU B C   1 
ATOM   3048 O O   . GLU B 1 39  ? 140.596 59.293  171.478 1.00 76.88  ? 36  GLU B O   1 
ATOM   3049 C CB  . GLU B 1 39  ? 143.098 60.845  171.311 1.00 74.88  ? 36  GLU B CB  1 
ATOM   3050 C CG  . GLU B 1 39  ? 142.178 62.011  171.658 1.00 79.41  ? 36  GLU B CG  1 
ATOM   3051 C CD  . GLU B 1 39  ? 141.897 62.946  170.489 1.00 94.30  ? 36  GLU B CD  1 
ATOM   3052 O OE1 . GLU B 1 39  ? 142.263 62.611  169.325 1.00 92.88  ? 36  GLU B OE1 1 
ATOM   3053 O OE2 . GLU B 1 39  ? 141.296 64.022  170.747 1.00 97.58  ? 36  GLU B OE2 1 
ATOM   3054 N N   . GLN B 1 40  ? 140.378 59.531  169.253 1.00 70.81  ? 37  GLN B N   1 
ATOM   3055 C CA  . GLN B 1 40  ? 138.949 59.215  169.248 1.00 64.21  ? 37  GLN B CA  1 
ATOM   3056 C C   . GLN B 1 40  ? 138.712 57.702  169.267 1.00 66.52  ? 37  GLN B C   1 
ATOM   3057 O O   . GLN B 1 40  ? 139.648 56.896  169.285 1.00 65.10  ? 37  GLN B O   1 
ATOM   3058 C CB  . GLN B 1 40  ? 138.243 59.853  168.058 1.00 60.58  ? 37  GLN B CB  1 
ATOM   3059 C CG  . GLN B 1 40  ? 138.174 61.369  168.104 1.00 68.52  ? 37  GLN B CG  1 
ATOM   3060 C CD  . GLN B 1 40  ? 137.282 61.962  167.010 1.00 73.98  ? 37  GLN B CD  1 
ATOM   3061 O OE1 . GLN B 1 40  ? 137.030 61.333  165.981 1.00 71.58  ? 37  GLN B OE1 1 
ATOM   3062 N NE2 . GLN B 1 40  ? 136.795 63.179  167.237 1.00 82.20  ? 37  GLN B NE2 1 
ATOM   3063 N N   . MET B 1 41  ? 137.430 57.313  169.252 1.00 65.15  ? 38  MET B N   1 
ATOM   3064 C CA  . MET B 1 41  ? 137.006 55.916  169.339 1.00 58.61  ? 38  MET B CA  1 
ATOM   3065 C C   . MET B 1 41  ? 135.644 55.721  168.689 1.00 60.30  ? 38  MET B C   1 
ATOM   3066 O O   . MET B 1 41  ? 134.736 56.533  168.884 1.00 60.21  ? 38  MET B O   1 
ATOM   3067 C CB  . MET B 1 41  ? 136.861 55.493  170.798 1.00 63.13  ? 38  MET B CB  1 
ATOM   3068 C CG  . MET B 1 41  ? 138.092 55.109  171.521 1.00 69.71  ? 38  MET B CG  1 
ATOM   3069 S SD  . MET B 1 41  ? 137.551 55.100  173.219 1.00 64.41  ? 38  MET B SD  1 
ATOM   3070 C CE  . MET B 1 41  ? 137.026 56.813  173.370 1.00 56.62  ? 38  MET B CE  1 
ATOM   3071 N N   . LEU B 1 42  ? 135.505 54.635  167.931 1.00 58.78  ? 39  LEU B N   1 
ATOM   3072 C CA  . LEU B 1 42  ? 134.219 54.228  167.379 1.00 58.22  ? 39  LEU B CA  1 
ATOM   3073 C C   . LEU B 1 42  ? 133.604 53.197  168.315 1.00 62.66  ? 39  LEU B C   1 
ATOM   3074 O O   . LEU B 1 42  ? 134.177 52.120  168.509 1.00 60.35  ? 39  LEU B O   1 
ATOM   3075 C CB  . LEU B 1 42  ? 134.367 53.648  165.978 1.00 62.38  ? 39  LEU B CB  1 
ATOM   3076 C CG  . LEU B 1 42  ? 133.055 53.059  165.465 1.00 64.80  ? 39  LEU B CG  1 
ATOM   3077 C CD1 . LEU B 1 42  ? 132.181 54.115  164.839 1.00 63.02  ? 39  LEU B CD1 1 
ATOM   3078 C CD2 . LEU B 1 42  ? 133.386 52.000  164.460 1.00 67.43  ? 39  LEU B CD2 1 
ATOM   3079 N N   . LEU B 1 43  ? 132.412 53.495  168.838 1.00 65.10  ? 40  LEU B N   1 
ATOM   3080 C CA  . LEU B 1 43  ? 131.803 52.712  169.904 1.00 56.51  ? 40  LEU B CA  1 
ATOM   3081 C C   . LEU B 1 43  ? 130.464 52.132  169.461 1.00 57.15  ? 40  LEU B C   1 
ATOM   3082 O O   . LEU B 1 43  ? 129.716 52.766  168.707 1.00 56.10  ? 40  LEU B O   1 
ATOM   3083 C CB  . LEU B 1 43  ? 131.629 53.570  171.157 1.00 53.35  ? 40  LEU B CB  1 
ATOM   3084 C CG  . LEU B 1 43  ? 132.966 53.980  171.784 1.00 56.21  ? 40  LEU B CG  1 
ATOM   3085 C CD1 . LEU B 1 43  ? 132.976 55.423  172.237 1.00 56.07  ? 40  LEU B CD1 1 
ATOM   3086 C CD2 . LEU B 1 43  ? 133.325 53.054  172.915 1.00 55.72  ? 40  LEU B CD2 1 
ATOM   3087 N N   . LYS B 1 44  ? 130.180 50.917  169.927 1.00 55.10  ? 41  LYS B N   1 
ATOM   3088 C CA  . LYS B 1 44  ? 128.918 50.233  169.679 1.00 53.62  ? 41  LYS B CA  1 
ATOM   3089 C C   . LYS B 1 44  ? 128.116 50.158  170.975 1.00 54.65  ? 41  LYS B C   1 
ATOM   3090 O O   . LYS B 1 44  ? 128.614 49.673  171.994 1.00 50.91  ? 41  LYS B O   1 
ATOM   3091 C CB  . LYS B 1 44  ? 129.150 48.829  169.117 1.00 50.81  ? 41  LYS B CB  1 
ATOM   3092 C CG  . LYS B 1 44  ? 127.855 48.060  168.835 1.00 59.97  ? 41  LYS B CG  1 
ATOM   3093 C CD  . LYS B 1 44  ? 128.083 46.542  168.643 1.00 70.89  ? 41  LYS B CD  1 
ATOM   3094 C CE  . LYS B 1 44  ? 126.925 45.863  167.847 1.00 74.59  ? 41  LYS B CE  1 
ATOM   3095 N NZ  . LYS B 1 44  ? 127.103 44.380  167.607 1.00 76.58  ? 41  LYS B NZ  1 
ATOM   3096 N N   . THR B 1 45  ? 126.876 50.627  170.930 1.00 52.40  ? 42  THR B N   1 
ATOM   3097 C CA  . THR B 1 45  ? 126.015 50.562  172.099 1.00 54.31  ? 42  THR B CA  1 
ATOM   3098 C C   . THR B 1 45  ? 125.511 49.136  172.319 1.00 54.18  ? 42  THR B C   1 
ATOM   3099 O O   . THR B 1 45  ? 124.874 48.557  171.438 1.00 58.92  ? 42  THR B O   1 
ATOM   3100 C CB  . THR B 1 45  ? 124.833 51.519  171.917 1.00 54.96  ? 42  THR B CB  1 
ATOM   3101 O OG1 . THR B 1 45  ? 125.307 52.867  171.822 1.00 56.21  ? 42  THR B OG1 1 
ATOM   3102 C CG2 . THR B 1 45  ? 123.887 51.429  173.085 1.00 57.07  ? 42  THR B CG2 1 
ATOM   3103 N N   . LEU B 1 46  ? 125.747 48.587  173.518 1.00 52.28  ? 43  LEU B N   1 
ATOM   3104 C CA  . LEU B 1 46  ? 125.226 47.274  173.909 1.00 55.32  ? 43  LEU B CA  1 
ATOM   3105 C C   . LEU B 1 46  ? 123.942 47.371  174.726 1.00 58.82  ? 43  LEU B C   1 
ATOM   3106 O O   . LEU B 1 46  ? 122.995 46.619  174.467 1.00 61.09  ? 43  LEU B O   1 
ATOM   3107 C CB  . LEU B 1 46  ? 126.247 46.467  174.727 1.00 52.98  ? 43  LEU B CB  1 
ATOM   3108 C CG  . LEU B 1 46  ? 127.701 46.266  174.311 1.00 56.30  ? 43  LEU B CG  1 
ATOM   3109 C CD1 . LEU B 1 46  ? 128.315 45.197  175.176 1.00 48.66  ? 43  LEU B CD1 1 
ATOM   3110 C CD2 . LEU B 1 46  ? 127.864 45.938  172.833 1.00 59.28  ? 43  LEU B CD2 1 
ATOM   3111 N N   . TYR B 1 47  ? 123.909 48.236  175.747 1.00 53.66  ? 44  TYR B N   1 
ATOM   3112 C CA  . TYR B 1 47  ? 122.696 48.526  176.495 1.00 46.97  ? 44  TYR B CA  1 
ATOM   3113 C C   . TYR B 1 47  ? 122.523 50.023  176.646 1.00 48.89  ? 44  TYR B C   1 
ATOM   3114 O O   . TYR B 1 47  ? 123.498 50.771  176.728 1.00 51.53  ? 44  TYR B O   1 
ATOM   3115 C CB  . TYR B 1 47  ? 122.709 47.971  177.866 1.00 52.12  ? 44  TYR B CB  1 
ATOM   3116 C CG  . TYR B 1 47  ? 122.935 46.503  178.005 1.00 53.19  ? 44  TYR B CG  1 
ATOM   3117 C CD1 . TYR B 1 47  ? 124.216 45.986  177.989 1.00 46.56  ? 44  TYR B CD1 1 
ATOM   3118 C CD2 . TYR B 1 47  ? 121.876 45.642  178.257 1.00 52.38  ? 44  TYR B CD2 1 
ATOM   3119 C CE1 . TYR B 1 47  ? 124.431 44.651  178.186 1.00 51.28  ? 44  TYR B CE1 1 
ATOM   3120 C CE2 . TYR B 1 47  ? 122.086 44.305  178.440 1.00 51.76  ? 44  TYR B CE2 1 
ATOM   3121 C CZ  . TYR B 1 47  ? 123.361 43.812  178.404 1.00 51.28  ? 44  TYR B CZ  1 
ATOM   3122 O OH  . TYR B 1 47  ? 123.580 42.468  178.585 1.00 58.50  ? 44  TYR B OH  1 
ATOM   3123 N N   . VAL B 1 48  ? 121.267 50.443  176.716 1.00 51.39  ? 45  VAL B N   1 
ATOM   3124 C CA  . VAL B 1 48  ? 120.896 51.828  176.967 1.00 51.19  ? 45  VAL B CA  1 
ATOM   3125 C C   . VAL B 1 48  ? 119.980 51.878  178.177 1.00 53.75  ? 45  VAL B C   1 
ATOM   3126 O O   . VAL B 1 48  ? 119.203 50.952  178.421 1.00 57.14  ? 45  VAL B O   1 
ATOM   3127 C CB  . VAL B 1 48  ? 120.207 52.444  175.729 1.00 48.40  ? 45  VAL B CB  1 
ATOM   3128 C CG1 . VAL B 1 48  ? 119.340 53.591  176.121 1.00 52.85  ? 45  VAL B CG1 1 
ATOM   3129 C CG2 . VAL B 1 48  ? 121.229 52.907  174.735 1.00 44.58  ? 45  VAL B CG2 1 
ATOM   3130 N N   . SER B 1 49  ? 120.048 52.979  178.921 1.00 54.80  ? 46  SER B N   1 
ATOM   3131 C CA  . SER B 1 49  ? 119.174 53.207  180.062 1.00 55.41  ? 46  SER B CA  1 
ATOM   3132 C C   . SER B 1 49  ? 118.048 54.173  179.709 1.00 57.91  ? 46  SER B C   1 
ATOM   3133 O O   . SER B 1 49  ? 118.257 55.161  179.001 1.00 60.27  ? 46  SER B O   1 
ATOM   3134 C CB  . SER B 1 49  ? 119.979 53.759  181.237 1.00 56.94  ? 46  SER B CB  1 
ATOM   3135 O OG  . SER B 1 49  ? 119.168 53.957  182.374 1.00 57.30  ? 46  SER B OG  1 
ATOM   3136 N N   . VAL B 1 50  ? 116.858 53.894  180.226 1.00 57.72  ? 47  VAL B N   1 
ATOM   3137 C CA  . VAL B 1 50  ? 115.728 54.810  180.154 1.00 57.58  ? 47  VAL B CA  1 
ATOM   3138 C C   . VAL B 1 50  ? 115.434 55.258  181.580 1.00 59.61  ? 47  VAL B C   1 
ATOM   3139 O O   . VAL B 1 50  ? 115.250 54.426  182.479 1.00 59.91  ? 47  VAL B O   1 
ATOM   3140 C CB  . VAL B 1 50  ? 114.503 54.164  179.481 1.00 60.21  ? 47  VAL B CB  1 
ATOM   3141 C CG1 . VAL B 1 50  ? 114.813 53.829  178.044 1.00 57.29  ? 47  VAL B CG1 1 
ATOM   3142 C CG2 . VAL B 1 50  ? 114.088 52.887  180.189 1.00 61.12  ? 47  VAL B CG2 1 
ATOM   3143 N N   . ASP B 1 51  ? 115.443 56.573  181.801 1.00 63.71  ? 48  ASP B N   1 
ATOM   3144 C CA  . ASP B 1 51  ? 115.378 57.127  183.145 1.00 58.95  ? 48  ASP B CA  1 
ATOM   3145 C C   . ASP B 1 51  ? 114.404 58.293  183.172 1.00 62.97  ? 48  ASP B C   1 
ATOM   3146 O O   . ASP B 1 51  ? 114.423 59.133  182.262 1.00 63.15  ? 48  ASP B O   1 
ATOM   3147 C CB  . ASP B 1 51  ? 116.757 57.612  183.576 1.00 56.71  ? 48  ASP B CB  1 
ATOM   3148 C CG  . ASP B 1 51  ? 117.805 56.527  183.457 1.00 65.99  ? 48  ASP B CG  1 
ATOM   3149 O OD1 . ASP B 1 51  ? 118.268 56.291  182.312 1.00 71.30  ? 48  ASP B OD1 1 
ATOM   3150 O OD2 . ASP B 1 51  ? 118.146 55.887  184.480 1.00 64.41  ? 48  ASP B OD2 1 
ATOM   3151 N N   . PRO B 1 52  ? 113.595 58.418  184.226 1.00 65.88  ? 49  PRO B N   1 
ATOM   3152 C CA  . PRO B 1 52  ? 112.618 59.516  184.253 1.00 66.00  ? 49  PRO B CA  1 
ATOM   3153 C C   . PRO B 1 52  ? 113.240 60.895  184.129 1.00 64.06  ? 49  PRO B C   1 
ATOM   3154 O O   . PRO B 1 52  ? 112.571 61.803  183.626 1.00 64.74  ? 49  PRO B O   1 
ATOM   3155 C CB  . PRO B 1 52  ? 111.909 59.311  185.597 1.00 66.39  ? 49  PRO B CB  1 
ATOM   3156 C CG  . PRO B 1 52  ? 112.029 57.844  185.837 1.00 70.18  ? 49  PRO B CG  1 
ATOM   3157 C CD  . PRO B 1 52  ? 113.399 57.487  185.351 1.00 67.56  ? 49  PRO B CD  1 
ATOM   3158 N N   . TYR B 1 53  ? 114.488 61.092  184.567 1.00 64.03  ? 50  TYR B N   1 
ATOM   3159 C CA  . TYR B 1 53  ? 115.115 62.400  184.401 1.00 63.27  ? 50  TYR B CA  1 
ATOM   3160 C C   . TYR B 1 53  ? 115.331 62.755  182.937 1.00 64.27  ? 50  TYR B C   1 
ATOM   3161 O O   . TYR B 1 53  ? 115.506 63.937  182.627 1.00 65.98  ? 50  TYR B O   1 
ATOM   3162 C CB  . TYR B 1 53  ? 116.441 62.500  185.170 1.00 61.42  ? 50  TYR B CB  1 
ATOM   3163 C CG  . TYR B 1 53  ? 117.551 61.557  184.747 1.00 60.52  ? 50  TYR B CG  1 
ATOM   3164 C CD1 . TYR B 1 53  ? 118.272 61.770  183.589 1.00 59.88  ? 50  TYR B CD1 1 
ATOM   3165 C CD2 . TYR B 1 53  ? 117.904 60.480  185.532 1.00 62.89  ? 50  TYR B CD2 1 
ATOM   3166 C CE1 . TYR B 1 53  ? 119.285 60.922  183.211 1.00 59.45  ? 50  TYR B CE1 1 
ATOM   3167 C CE2 . TYR B 1 53  ? 118.921 59.632  185.166 1.00 61.92  ? 50  TYR B CE2 1 
ATOM   3168 C CZ  . TYR B 1 53  ? 119.608 59.852  184.001 1.00 59.66  ? 50  TYR B CZ  1 
ATOM   3169 O OH  . TYR B 1 53  ? 120.630 59.002  183.626 1.00 55.44  ? 50  TYR B OH  1 
ATOM   3170 N N   . LEU B 1 54  ? 115.330 61.765  182.032 1.00 65.86  ? 51  LEU B N   1 
ATOM   3171 C CA  . LEU B 1 54  ? 115.454 62.050  180.600 1.00 64.27  ? 51  LEU B CA  1 
ATOM   3172 C C   . LEU B 1 54  ? 114.366 62.999  180.115 1.00 68.41  ? 51  LEU B C   1 
ATOM   3173 O O   . LEU B 1 54  ? 114.586 63.745  179.155 1.00 68.66  ? 51  LEU B O   1 
ATOM   3174 C CB  . LEU B 1 54  ? 115.395 60.746  179.804 1.00 60.52  ? 51  LEU B CB  1 
ATOM   3175 C CG  . LEU B 1 54  ? 116.566 59.795  180.042 1.00 59.96  ? 51  LEU B CG  1 
ATOM   3176 C CD1 . LEU B 1 54  ? 116.402 58.515  179.258 1.00 54.73  ? 51  LEU B CD1 1 
ATOM   3177 C CD2 . LEU B 1 54  ? 117.866 60.482  179.689 1.00 55.24  ? 51  LEU B CD2 1 
ATOM   3178 N N   . GLN B 1 55  ? 113.210 63.020  180.799 1.00 69.74  ? 52  GLN B N   1 
ATOM   3179 C CA  . GLN B 1 55  ? 112.156 63.988  180.501 1.00 66.16  ? 52  GLN B CA  1 
ATOM   3180 C C   . GLN B 1 55  ? 112.679 65.414  180.537 1.00 67.66  ? 52  GLN B C   1 
ATOM   3181 O O   . GLN B 1 55  ? 112.250 66.251  179.739 1.00 70.05  ? 52  GLN B O   1 
ATOM   3182 C CB  . GLN B 1 55  ? 111.013 63.835  181.505 1.00 67.20  ? 52  GLN B CB  1 
ATOM   3183 C CG  . GLN B 1 55  ? 109.736 64.651  181.225 1.00 72.94  ? 52  GLN B CG  1 
ATOM   3184 C CD  . GLN B 1 55  ? 109.759 66.074  181.804 1.00 74.21  ? 52  GLN B CD  1 
ATOM   3185 O OE1 . GLN B 1 55  ? 110.747 66.504  182.406 1.00 69.51  ? 52  GLN B OE1 1 
ATOM   3186 N NE2 . GLN B 1 55  ? 108.645 66.796  181.644 1.00 79.36  ? 52  GLN B NE2 1 
ATOM   3187 N N   . GLY B 1 56  ? 113.617 65.702  181.428 1.00 65.43  ? 53  GLY B N   1 
ATOM   3188 C CA  . GLY B 1 56  ? 114.204 67.022  181.480 1.00 67.21  ? 53  GLY B CA  1 
ATOM   3189 C C   . GLY B 1 56  ? 115.236 67.258  180.397 1.00 70.24  ? 53  GLY B C   1 
ATOM   3190 O O   . GLY B 1 56  ? 115.307 68.348  179.820 1.00 74.08  ? 53  GLY B O   1 
ATOM   3191 N N   . ILE B 1 57  ? 116.078 66.256  180.148 1.00 70.73  ? 54  ILE B N   1 
ATOM   3192 C CA  . ILE B 1 57  ? 117.096 66.383  179.112 1.00 72.08  ? 54  ILE B CA  1 
ATOM   3193 C C   . ILE B 1 57  ? 116.446 66.492  177.740 1.00 74.95  ? 54  ILE B C   1 
ATOM   3194 O O   . ILE B 1 57  ? 116.960 67.178  176.845 1.00 78.72  ? 54  ILE B O   1 
ATOM   3195 C CB  . ILE B 1 57  ? 118.077 65.204  179.196 1.00 70.55  ? 54  ILE B CB  1 
ATOM   3196 C CG1 . ILE B 1 57  ? 118.776 65.233  180.540 1.00 66.14  ? 54  ILE B CG1 1 
ATOM   3197 C CG2 . ILE B 1 57  ? 119.153 65.323  178.148 1.00 75.55  ? 54  ILE B CG2 1 
ATOM   3198 C CD1 . ILE B 1 57  ? 119.543 64.006  180.817 1.00 70.40  ? 54  ILE B CD1 1 
ATOM   3199 N N   . CYS B 1 58  ? 115.321 65.796  177.542 1.00 70.98  ? 55  CYS B N   1 
ATOM   3200 C CA  . CYS B 1 58  ? 114.636 65.849  176.254 1.00 72.29  ? 55  CYS B CA  1 
ATOM   3201 C C   . CYS B 1 58  ? 114.164 67.259  175.944 1.00 76.00  ? 55  CYS B C   1 
ATOM   3202 O O   . CYS B 1 58  ? 114.205 67.689  174.786 1.00 81.30  ? 55  CYS B O   1 
ATOM   3203 C CB  . CYS B 1 58  ? 113.456 64.886  176.234 1.00 71.62  ? 55  CYS B CB  1 
ATOM   3204 S SG  . CYS B 1 58  ? 112.653 64.754  174.646 1.00 73.47  ? 55  CYS B SG  1 
ATOM   3205 N N   . LEU B 1 59  ? 113.707 67.990  176.968 1.00 71.77  ? 56  LEU B N   1 
ATOM   3206 C CA  . LEU B 1 59  ? 113.248 69.361  176.778 1.00 71.91  ? 56  LEU B CA  1 
ATOM   3207 C C   . LEU B 1 59  ? 114.404 70.323  176.559 1.00 73.25  ? 56  LEU B C   1 
ATOM   3208 O O   . LEU B 1 59  ? 114.223 71.373  175.935 1.00 74.20  ? 56  LEU B O   1 
ATOM   3209 C CB  . LEU B 1 59  ? 112.424 69.798  177.985 1.00 64.48  ? 56  LEU B CB  1 
ATOM   3210 C CG  . LEU B 1 59  ? 111.131 69.002  178.132 1.00 74.33  ? 56  LEU B CG  1 
ATOM   3211 C CD1 . LEU B 1 59  ? 110.384 69.447  179.362 1.00 77.56  ? 56  LEU B CD1 1 
ATOM   3212 C CD2 . LEU B 1 59  ? 110.262 69.133  176.887 1.00 74.73  ? 56  LEU B CD2 1 
ATOM   3213 N N   . ASP B 1 60  ? 115.596 69.960  177.004 1.00 74.95  ? 57  ASP B N   1 
ATOM   3214 C CA  . ASP B 1 60  ? 116.786 70.763  176.795 1.00 78.98  ? 57  ASP B CA  1 
ATOM   3215 C C   . ASP B 1 60  ? 117.596 70.246  175.624 1.00 80.39  ? 57  ASP B C   1 
ATOM   3216 O O   . ASP B 1 60  ? 118.625 70.836  175.283 1.00 83.04  ? 57  ASP B O   1 
ATOM   3217 C CB  . ASP B 1 60  ? 117.659 70.772  178.062 1.00 82.19  ? 57  ASP B CB  1 
ATOM   3218 C CG  . ASP B 1 60  ? 117.177 71.757  179.112 1.00 82.97  ? 57  ASP B CG  1 
ATOM   3219 O OD1 . ASP B 1 60  ? 116.315 72.596  178.787 1.00 85.50  ? 57  ASP B OD1 1 
ATOM   3220 O OD2 . ASP B 1 60  ? 117.677 71.705  180.259 1.00 86.14  ? 57  ASP B OD2 1 
ATOM   3221 N N   . THR B 1 61  ? 117.157 69.162  175.006 1.00 76.41  ? 58  THR B N   1 
ATOM   3222 C CA  . THR B 1 61  ? 117.846 68.654  173.841 1.00 79.36  ? 58  THR B CA  1 
ATOM   3223 C C   . THR B 1 61  ? 117.375 69.438  172.625 1.00 80.51  ? 58  THR B C   1 
ATOM   3224 O O   . THR B 1 61  ? 116.172 69.437  172.330 1.00 73.88  ? 58  THR B O   1 
ATOM   3225 C CB  . THR B 1 61  ? 117.575 67.171  173.653 1.00 82.10  ? 58  THR B CB  1 
ATOM   3226 O OG1 . THR B 1 61  ? 118.263 66.431  174.676 1.00 79.45  ? 58  THR B OG1 1 
ATOM   3227 C CG2 . THR B 1 61  ? 118.059 66.727  172.271 1.00 76.55  ? 58  THR B CG2 1 
ATOM   3228 N N   . PRO B 1 62  ? 118.267 70.158  171.938 1.00 86.03  ? 59  PRO B N   1 
ATOM   3229 C CA  . PRO B 1 62  ? 117.867 70.906  170.738 1.00 79.53  ? 59  PRO B CA  1 
ATOM   3230 C C   . PRO B 1 62  ? 117.159 69.999  169.735 1.00 79.35  ? 59  PRO B C   1 
ATOM   3231 O O   . PRO B 1 62  ? 117.524 68.834  169.567 1.00 82.30  ? 59  PRO B O   1 
ATOM   3232 C CB  . PRO B 1 62  ? 119.199 71.438  170.202 1.00 73.40  ? 59  PRO B CB  1 
ATOM   3233 C CG  . PRO B 1 62  ? 120.071 71.538  171.420 1.00 80.34  ? 59  PRO B CG  1 
ATOM   3234 C CD  . PRO B 1 62  ? 119.685 70.372  172.282 1.00 83.71  ? 59  PRO B CD  1 
ATOM   3235 N N   . ILE B 1 63  ? 116.130 70.539  169.065 1.00 85.45  ? 60  ILE B N   1 
ATOM   3236 C CA  . ILE B 1 63  ? 115.304 69.736  168.155 1.00 82.10  ? 60  ILE B CA  1 
ATOM   3237 C C   . ILE B 1 63  ? 116.135 69.114  167.045 1.00 76.05  ? 60  ILE B C   1 
ATOM   3238 O O   . ILE B 1 63  ? 116.890 69.800  166.342 1.00 73.77  ? 60  ILE B O   1 
ATOM   3239 C CB  . ILE B 1 63  ? 114.169 70.582  167.562 1.00 72.76  ? 60  ILE B CB  1 
ATOM   3240 C CG1 . ILE B 1 63  ? 113.154 70.941  168.637 1.00 75.98  ? 60  ILE B CG1 1 
ATOM   3241 C CG2 . ILE B 1 63  ? 113.455 69.807  166.481 1.00 70.32  ? 60  ILE B CG2 1 
ATOM   3242 C CD1 . ILE B 1 63  ? 112.065 69.883  168.807 1.00 78.16  ? 60  ILE B CD1 1 
ATOM   3243 N N   . GLY B 1 64  ? 115.965 67.803  166.861 1.00 71.49  ? 61  GLY B N   1 
ATOM   3244 C CA  . GLY B 1 64  ? 116.662 67.060  165.841 1.00 76.28  ? 61  GLY B CA  1 
ATOM   3245 C C   . GLY B 1 64  ? 117.873 66.296  166.327 1.00 77.67  ? 61  GLY B C   1 
ATOM   3246 O O   . GLY B 1 64  ? 118.315 65.354  165.653 1.00 80.45  ? 61  GLY B O   1 
ATOM   3247 N N   . ASP B 1 65  ? 118.408 66.659  167.479 1.00 77.07  ? 62  ASP B N   1 
ATOM   3248 C CA  . ASP B 1 65  ? 119.586 65.991  167.992 1.00 74.21  ? 62  ASP B CA  1 
ATOM   3249 C C   . ASP B 1 65  ? 119.188 64.683  168.664 1.00 76.22  ? 62  ASP B C   1 
ATOM   3250 O O   . ASP B 1 65  ? 118.012 64.436  168.947 1.00 76.89  ? 62  ASP B O   1 
ATOM   3251 C CB  . ASP B 1 65  ? 120.308 66.901  168.972 1.00 77.60  ? 62  ASP B CB  1 
ATOM   3252 C CG  . ASP B 1 65  ? 120.821 68.155  168.314 1.00 83.50  ? 62  ASP B CG  1 
ATOM   3253 O OD1 . ASP B 1 65  ? 120.494 68.366  167.117 1.00 84.50  ? 62  ASP B OD1 1 
ATOM   3254 O OD2 . ASP B 1 65  ? 121.505 68.948  169.002 1.00 82.23  ? 62  ASP B OD2 1 
ATOM   3255 N N   . HIS B 1 66  ? 120.194 63.887  168.996 1.00 75.10  ? 63  HIS B N   1 
ATOM   3256 C CA  . HIS B 1 66  ? 119.931 62.600  169.604 1.00 65.86  ? 63  HIS B CA  1 
ATOM   3257 C C   . HIS B 1 66  ? 119.567 62.722  171.052 1.00 66.93  ? 63  HIS B C   1 
ATOM   3258 O O   . HIS B 1 66  ? 119.973 63.656  171.730 1.00 68.01  ? 63  HIS B O   1 
ATOM   3259 C CB  . HIS B 1 66  ? 121.130 61.662  169.413 1.00 60.94  ? 63  HIS B CB  1 
ATOM   3260 C CG  . HIS B 1 66  ? 122.119 61.668  170.531 1.00 61.71  ? 63  HIS B CG  1 
ATOM   3261 N ND1 . HIS B 1 66  ? 123.204 62.515  170.557 1.00 66.88  ? 63  HIS B ND1 1 
ATOM   3262 C CD2 . HIS B 1 66  ? 122.223 60.891  171.634 1.00 62.12  ? 63  HIS B CD2 1 
ATOM   3263 C CE1 . HIS B 1 66  ? 123.916 62.281  171.644 1.00 64.23  ? 63  HIS B CE1 1 
ATOM   3264 N NE2 . HIS B 1 66  ? 123.342 61.300  172.314 1.00 64.77  ? 63  HIS B NE2 1 
ATOM   3265 N N   . MET B 1 67  ? 118.797 61.763  171.544 1.00 66.15  ? 64  MET B N   1 
ATOM   3266 C CA  . MET B 1 67  ? 118.401 61.766  172.933 1.00 59.87  ? 64  MET B CA  1 
ATOM   3267 C C   . MET B 1 67  ? 119.505 61.220  173.777 1.00 59.93  ? 64  MET B C   1 
ATOM   3268 O O   . MET B 1 67  ? 119.912 60.079  173.614 1.00 57.85  ? 64  MET B O   1 
ATOM   3269 C CB  . MET B 1 67  ? 117.183 60.892  173.133 1.00 65.80  ? 64  MET B CB  1 
ATOM   3270 C CG  . MET B 1 67  ? 116.709 60.823  174.569 1.00 65.10  ? 64  MET B CG  1 
ATOM   3271 S SD  . MET B 1 67  ? 116.056 62.412  175.086 1.00 63.22  ? 64  MET B SD  1 
ATOM   3272 C CE  . MET B 1 67  ? 117.194 62.829  176.397 1.00 66.40  ? 64  MET B CE  1 
ATOM   3273 N N   . GLY B 1 68  ? 119.995 62.032  174.694 1.00 60.52  ? 65  GLY B N   1 
ATOM   3274 C CA  . GLY B 1 68  ? 121.022 61.555  175.600 1.00 62.04  ? 65  GLY B CA  1 
ATOM   3275 C C   . GLY B 1 68  ? 120.515 60.457  176.522 1.00 58.30  ? 65  GLY B C   1 
ATOM   3276 O O   . GLY B 1 68  ? 119.317 60.321  176.788 1.00 55.14  ? 65  GLY B O   1 
ATOM   3277 N N   . ALA B 1 69  ? 121.460 59.668  177.035 1.00 52.80  ? 66  ALA B N   1 
ATOM   3278 C CA  . ALA B 1 69  ? 121.134 58.543  177.897 1.00 51.84  ? 66  ALA B CA  1 
ATOM   3279 C C   . ALA B 1 69  ? 122.387 57.839  178.379 1.00 54.31  ? 66  ALA B C   1 
ATOM   3280 O O   . ALA B 1 69  ? 123.377 57.746  177.643 1.00 50.32  ? 66  ALA B O   1 
ATOM   3281 C CB  . ALA B 1 69  ? 120.256 57.530  177.167 1.00 54.11  ? 66  ALA B CB  1 
ATOM   3282 N N   . ASP B 1 70  ? 122.356 57.344  179.615 1.00 56.16  ? 67  ASP B N   1 
ATOM   3283 C CA  . ASP B 1 70  ? 123.408 56.449  180.069 1.00 52.63  ? 67  ASP B CA  1 
ATOM   3284 C C   . ASP B 1 70  ? 123.415 55.180  179.224 1.00 55.29  ? 67  ASP B C   1 
ATOM   3285 O O   . ASP B 1 70  ? 122.361 54.628  178.902 1.00 57.59  ? 67  ASP B O   1 
ATOM   3286 C CB  . ASP B 1 70  ? 123.204 56.106  181.532 1.00 50.65  ? 67  ASP B CB  1 
ATOM   3287 C CG  . ASP B 1 70  ? 124.497 56.139  182.307 1.00 61.59  ? 67  ASP B CG  1 
ATOM   3288 O OD1 . ASP B 1 70  ? 125.437 56.769  181.776 1.00 58.32  ? 67  ASP B OD1 1 
ATOM   3289 O OD2 . ASP B 1 70  ? 124.584 55.539  183.423 1.00 64.70  ? 67  ASP B OD2 1 
ATOM   3290 N N   . SER B 1 71  ? 124.603 54.725  178.831 1.00 54.43  ? 68  SER B N   1 
ATOM   3291 C CA  . SER B 1 71  ? 124.681 53.518  178.024 1.00 50.29  ? 68  SER B CA  1 
ATOM   3292 C C   . SER B 1 71  ? 125.917 52.718  178.387 1.00 51.48  ? 68  SER B C   1 
ATOM   3293 O O   . SER B 1 71  ? 126.838 53.208  179.047 1.00 54.37  ? 68  SER B O   1 
ATOM   3294 C CB  . SER B 1 71  ? 124.704 53.827  176.526 1.00 57.35  ? 68  SER B CB  1 
ATOM   3295 O OG  . SER B 1 71  ? 125.843 54.588  176.162 1.00 61.61  ? 68  SER B OG  1 
ATOM   3296 N N   . ILE B 1 72  ? 125.910 51.460  177.960 1.00 53.31  ? 69  ILE B N   1 
ATOM   3297 C CA  . ILE B 1 72  ? 127.085 50.595  178.007 1.00 57.17  ? 69  ILE B CA  1 
ATOM   3298 C C   . ILE B 1 72  ? 127.479 50.311  176.557 1.00 55.44  ? 69  ILE B C   1 
ATOM   3299 O O   . ILE B 1 72  ? 126.680 49.755  175.791 1.00 50.81  ? 69  ILE B O   1 
ATOM   3300 C CB  . ILE B 1 72  ? 126.800 49.296  178.778 1.00 55.51  ? 69  ILE B CB  1 
ATOM   3301 C CG1 . ILE B 1 72  ? 126.373 49.602  180.196 1.00 49.68  ? 69  ILE B CG1 1 
ATOM   3302 C CG2 . ILE B 1 72  ? 128.052 48.435  178.885 1.00 57.08  ? 69  ILE B CG2 1 
ATOM   3303 C CD1 . ILE B 1 72  ? 125.970 48.372  180.950 1.00 51.37  ? 69  ILE B CD1 1 
ATOM   3304 N N   . MET B 1 73  ? 128.715 50.678  176.190 1.00 54.24  ? 70  MET B N   1 
ATOM   3305 C CA  . MET B 1 73  ? 129.197 50.642  174.816 1.00 52.49  ? 70  MET B CA  1 
ATOM   3306 C C   . MET B 1 73  ? 130.495 49.848  174.731 1.00 54.51  ? 70  MET B C   1 
ATOM   3307 O O   . MET B 1 73  ? 131.232 49.727  175.713 1.00 58.90  ? 70  MET B O   1 
ATOM   3308 C CB  . MET B 1 73  ? 129.417 52.057  174.282 1.00 52.88  ? 70  MET B CB  1 
ATOM   3309 C CG  . MET B 1 73  ? 128.166 52.911  174.297 1.00 54.25  ? 70  MET B CG  1 
ATOM   3310 S SD  . MET B 1 73  ? 128.569 54.664  174.306 1.00 62.26  ? 70  MET B SD  1 
ATOM   3311 C CE  . MET B 1 73  ? 129.498 54.797  175.807 1.00 55.42  ? 70  MET B CE  1 
ATOM   3312 N N   . GLN B 1 74  ? 130.789 49.310  173.544 1.00 53.08  ? 71  GLN B N   1 
ATOM   3313 C CA  . GLN B 1 74  ? 132.034 48.577  173.313 1.00 54.99  ? 71  GLN B CA  1 
ATOM   3314 C C   . GLN B 1 74  ? 132.906 49.274  172.268 1.00 54.70  ? 71  GLN B C   1 
ATOM   3315 O O   . GLN B 1 74  ? 132.392 49.860  171.310 1.00 56.10  ? 71  GLN B O   1 
ATOM   3316 C CB  . GLN B 1 74  ? 131.750 47.133  172.902 1.00 47.03  ? 71  GLN B CB  1 
ATOM   3317 C CG  . GLN B 1 74  ? 133.002 46.300  172.855 1.00 51.16  ? 71  GLN B CG  1 
ATOM   3318 C CD  . GLN B 1 74  ? 132.714 44.824  172.988 1.00 57.95  ? 71  GLN B CD  1 
ATOM   3319 O OE1 . GLN B 1 74  ? 131.592 44.369  172.729 1.00 52.73  ? 71  GLN B OE1 1 
ATOM   3320 N NE2 . GLN B 1 74  ? 133.729 44.059  173.397 1.00 55.94  ? 71  GLN B NE2 1 
ATOM   3321 N N   . VAL B 1 75  ? 134.224 49.232  172.460 1.00 51.45  ? 72  VAL B N   1 
ATOM   3322 C CA  . VAL B 1 75  ? 135.143 49.942  171.573 1.00 53.96  ? 72  VAL B CA  1 
ATOM   3323 C C   . VAL B 1 75  ? 135.335 49.098  170.318 1.00 58.71  ? 72  VAL B C   1 
ATOM   3324 O O   . VAL B 1 75  ? 136.068 48.113  170.338 1.00 63.15  ? 72  VAL B O   1 
ATOM   3325 C CB  . VAL B 1 75  ? 136.480 50.239  172.249 1.00 53.94  ? 72  VAL B CB  1 
ATOM   3326 C CG1 . VAL B 1 75  ? 137.402 50.949  171.286 1.00 56.80  ? 72  VAL B CG1 1 
ATOM   3327 C CG2 . VAL B 1 75  ? 136.261 51.093  173.470 1.00 57.77  ? 72  VAL B CG2 1 
ATOM   3328 N N   . LEU B 1 76  ? 134.690 49.503  169.212 1.00 62.34  ? 73  LEU B N   1 
ATOM   3329 C CA  . LEU B 1 76  ? 134.882 48.835  167.920 1.00 60.30  ? 73  LEU B CA  1 
ATOM   3330 C C   . LEU B 1 76  ? 136.264 49.106  167.350 1.00 59.24  ? 73  LEU B C   1 
ATOM   3331 O O   . LEU B 1 76  ? 136.851 48.236  166.703 1.00 58.66  ? 73  LEU B O   1 
ATOM   3332 C CB  . LEU B 1 76  ? 133.829 49.286  166.906 1.00 50.99  ? 73  LEU B CB  1 
ATOM   3333 C CG  . LEU B 1 76  ? 132.442 48.697  167.058 1.00 47.61  ? 73  LEU B CG  1 
ATOM   3334 C CD1 . LEU B 1 76  ? 131.483 49.442  166.176 1.00 50.96  ? 73  LEU B CD1 1 
ATOM   3335 C CD2 . LEU B 1 76  ? 132.500 47.237  166.696 1.00 35.84  ? 73  LEU B CD2 1 
ATOM   3336 N N   . ASP B 1 77  ? 136.767 50.325  167.524 1.00 61.70  ? 74  ASP B N   1 
ATOM   3337 C CA  . ASP B 1 77  ? 137.989 50.766  166.876 1.00 61.11  ? 74  ASP B CA  1 
ATOM   3338 C C   . ASP B 1 77  ? 138.400 52.085  167.496 1.00 59.73  ? 74  ASP B C   1 
ATOM   3339 O O   . ASP B 1 77  ? 137.544 52.917  167.800 1.00 58.39  ? 74  ASP B O   1 
ATOM   3340 C CB  . ASP B 1 77  ? 137.781 50.913  165.367 1.00 71.61  ? 74  ASP B CB  1 
ATOM   3341 C CG  . ASP B 1 77  ? 139.076 51.126  164.614 1.00 71.27  ? 74  ASP B CG  1 
ATOM   3342 O OD1 . ASP B 1 77  ? 140.154 51.161  165.246 1.00 66.09  ? 74  ASP B OD1 1 
ATOM   3343 O OD2 . ASP B 1 77  ? 139.004 51.227  163.374 1.00 79.70  ? 74  ASP B OD2 1 
ATOM   3344 N N   . ALA B 1 78  ? 139.706 52.268  167.667 1.00 59.81  ? 75  ALA B N   1 
ATOM   3345 C CA  . ALA B 1 78  ? 140.234 53.406  168.401 1.00 65.09  ? 75  ALA B CA  1 
ATOM   3346 C C   . ALA B 1 78  ? 141.536 53.895  167.782 1.00 63.40  ? 75  ALA B C   1 
ATOM   3347 O O   . ALA B 1 78  ? 142.346 53.095  167.304 1.00 57.05  ? 75  ALA B O   1 
ATOM   3348 C CB  . ALA B 1 78  ? 140.456 53.047  169.881 1.00 65.48  ? 75  ALA B CB  1 
ATOM   3349 N N   . GLY B 1 79  ? 141.725 55.212  167.782 1.00 66.55  ? 76  GLY B N   1 
ATOM   3350 C CA  . GLY B 1 79  ? 142.984 55.794  167.390 1.00 66.17  ? 76  GLY B CA  1 
ATOM   3351 C C   . GLY B 1 79  ? 144.126 55.420  168.320 1.00 72.53  ? 76  GLY B C   1 
ATOM   3352 O O   . GLY B 1 79  ? 143.930 54.854  169.400 1.00 73.11  ? 76  GLY B O   1 
ATOM   3353 N N   . PRO B 1 80  ? 145.354 55.766  167.921 1.00 78.92  ? 77  PRO B N   1 
ATOM   3354 C CA  . PRO B 1 80  ? 146.538 55.321  168.680 1.00 73.43  ? 77  PRO B CA  1 
ATOM   3355 C C   . PRO B 1 80  ? 146.699 55.965  170.048 1.00 75.67  ? 77  PRO B C   1 
ATOM   3356 O O   . PRO B 1 80  ? 147.465 55.430  170.855 1.00 86.79  ? 77  PRO B O   1 
ATOM   3357 C CB  . PRO B 1 80  ? 147.709 55.683  167.756 1.00 78.37  ? 77  PRO B CB  1 
ATOM   3358 C CG  . PRO B 1 80  ? 147.178 56.770  166.870 1.00 78.59  ? 77  PRO B CG  1 
ATOM   3359 C CD  . PRO B 1 80  ? 145.723 56.440  166.663 1.00 79.50  ? 77  PRO B CD  1 
ATOM   3360 N N   . ASN B 1 81  ? 146.075 57.114  170.325 1.00 73.47  ? 78  ASN B N   1 
ATOM   3361 C CA  . ASN B 1 81  ? 146.126 57.713  171.657 1.00 74.18  ? 78  ASN B CA  1 
ATOM   3362 C C   . ASN B 1 81  ? 144.775 57.697  172.342 1.00 77.08  ? 78  ASN B C   1 
ATOM   3363 O O   . ASN B 1 81  ? 144.569 58.429  173.319 1.00 78.41  ? 78  ASN B O   1 
ATOM   3364 C CB  . ASN B 1 81  ? 146.649 59.147  171.644 1.00 77.18  ? 78  ASN B CB  1 
ATOM   3365 C CG  . ASN B 1 81  ? 148.094 59.235  171.266 1.00 82.58  ? 78  ASN B CG  1 
ATOM   3366 O OD1 . ASN B 1 81  ? 148.875 58.305  171.492 1.00 77.12  ? 78  ASN B OD1 1 
ATOM   3367 N ND2 . ASN B 1 81  ? 148.484 60.384  170.738 1.00 88.26  ? 78  ASN B ND2 1 
ATOM   3368 N N   . ALA B 1 82  ? 143.842 56.906  171.829 1.00 74.51  ? 79  ALA B N   1 
ATOM   3369 C CA  . ALA B 1 82  ? 142.532 56.836  172.444 1.00 76.58  ? 79  ALA B CA  1 
ATOM   3370 C C   . ALA B 1 82  ? 142.681 56.397  173.902 1.00 75.77  ? 79  ALA B C   1 
ATOM   3371 O O   . ALA B 1 82  ? 143.636 55.699  174.256 1.00 76.39  ? 79  ALA B O   1 
ATOM   3372 C CB  . ALA B 1 82  ? 141.641 55.862  171.678 1.00 75.30  ? 79  ALA B CB  1 
ATOM   3373 N N   . PRO B 1 83  ? 141.766 56.804  174.779 1.00 72.26  ? 80  PRO B N   1 
ATOM   3374 C CA  . PRO B 1 83  ? 141.846 56.330  176.166 1.00 69.14  ? 80  PRO B CA  1 
ATOM   3375 C C   . PRO B 1 83  ? 141.529 54.849  176.329 1.00 71.25  ? 80  PRO B C   1 
ATOM   3376 O O   . PRO B 1 83  ? 141.885 54.276  177.370 1.00 63.36  ? 80  PRO B O   1 
ATOM   3377 C CB  . PRO B 1 83  ? 140.825 57.210  176.899 1.00 62.70  ? 80  PRO B CB  1 
ATOM   3378 C CG  . PRO B 1 83  ? 139.982 57.822  175.824 1.00 66.84  ? 80  PRO B CG  1 
ATOM   3379 C CD  . PRO B 1 83  ? 140.842 57.936  174.624 1.00 70.88  ? 80  PRO B CD  1 
ATOM   3380 N N   . PHE B 1 84  ? 140.919 54.199  175.332 1.00 69.07  ? 81  PHE B N   1 
ATOM   3381 C CA  . PHE B 1 84  ? 140.533 52.800  175.462 1.00 64.53  ? 81  PHE B CA  1 
ATOM   3382 C C   . PHE B 1 84  ? 140.818 52.080  174.158 1.00 65.55  ? 81  PHE B C   1 
ATOM   3383 O O   . PHE B 1 84  ? 140.609 52.638  173.078 1.00 70.42  ? 81  PHE B O   1 
ATOM   3384 C CB  . PHE B 1 84  ? 139.040 52.600  175.799 1.00 64.35  ? 81  PHE B CB  1 
ATOM   3385 C CG  . PHE B 1 84  ? 138.531 53.432  176.956 1.00 60.92  ? 81  PHE B CG  1 
ATOM   3386 C CD1 . PHE B 1 84  ? 138.834 53.094  178.267 1.00 56.48  ? 81  PHE B CD1 1 
ATOM   3387 C CD2 . PHE B 1 84  ? 137.690 54.522  176.726 1.00 53.97  ? 81  PHE B CD2 1 
ATOM   3388 C CE1 . PHE B 1 84  ? 138.330 53.855  179.326 1.00 54.14  ? 81  PHE B CE1 1 
ATOM   3389 C CE2 . PHE B 1 84  ? 137.189 55.277  177.773 1.00 53.31  ? 81  PHE B CE2 1 
ATOM   3390 C CZ  . PHE B 1 84  ? 137.512 54.947  179.077 1.00 50.64  ? 81  PHE B CZ  1 
ATOM   3391 N N   . ARG B 1 85  ? 141.224 50.812  174.268 1.00 66.56  ? 82  ARG B N   1 
ATOM   3392 C CA  . ARG B 1 85  ? 141.582 49.982  173.133 1.00 65.53  ? 82  ARG B CA  1 
ATOM   3393 C C   . ARG B 1 85  ? 140.362 49.253  172.611 1.00 60.70  ? 82  ARG B C   1 
ATOM   3394 O O   . ARG B 1 85  ? 139.309 49.246  173.246 1.00 61.97  ? 82  ARG B O   1 
ATOM   3395 C CB  . ARG B 1 85  ? 142.665 48.977  173.535 1.00 63.82  ? 82  ARG B CB  1 
ATOM   3396 C CG  . ARG B 1 85  ? 144.051 49.610  173.566 1.00 76.23  ? 82  ARG B CG  1 
ATOM   3397 C CD  . ARG B 1 85  ? 145.172 48.621  173.869 1.00 95.38  ? 82  ARG B CD  1 
ATOM   3398 N NE  . ARG B 1 85  ? 146.360 49.318  174.358 1.00 106.47 ? 82  ARG B NE  1 
ATOM   3399 C CZ  . ARG B 1 85  ? 147.419 48.732  174.909 1.00 105.60 ? 82  ARG B CZ  1 
ATOM   3400 N NH1 . ARG B 1 85  ? 147.471 47.421  175.086 1.00 101.83 ? 82  ARG B NH1 1 
ATOM   3401 N NH2 . ARG B 1 85  ? 148.440 49.486  175.317 1.00 104.45 ? 82  ARG B NH2 1 
ATOM   3402 N N   . PRO B 1 86  ? 140.451 48.709  171.406 1.00 62.91  ? 83  PRO B N   1 
ATOM   3403 C CA  . PRO B 1 86  ? 139.327 47.947  170.853 1.00 64.15  ? 83  PRO B CA  1 
ATOM   3404 C C   . PRO B 1 86  ? 138.984 46.729  171.703 1.00 61.88  ? 83  PRO B C   1 
ATOM   3405 O O   . PRO B 1 86  ? 139.864 46.053  172.243 1.00 60.59  ? 83  PRO B O   1 
ATOM   3406 C CB  . PRO B 1 86  ? 139.836 47.545  169.467 1.00 55.05  ? 83  PRO B CB  1 
ATOM   3407 C CG  . PRO B 1 86  ? 140.784 48.628  169.120 1.00 59.68  ? 83  PRO B CG  1 
ATOM   3408 C CD  . PRO B 1 86  ? 141.463 49.010  170.382 1.00 61.58  ? 83  PRO B CD  1 
ATOM   3409 N N   . GLY B 1 87  ? 137.682 46.466  171.833 1.00 56.84  ? 84  GLY B N   1 
ATOM   3410 C CA  . GLY B 1 87  ? 137.190 45.386  172.644 1.00 57.79  ? 84  GLY B CA  1 
ATOM   3411 C C   . GLY B 1 87  ? 136.786 45.816  174.029 1.00 63.26  ? 84  GLY B C   1 
ATOM   3412 O O   . GLY B 1 87  ? 136.006 45.115  174.681 1.00 63.30  ? 84  GLY B O   1 
ATOM   3413 N N   . ASP B 1 88  ? 137.321 46.944  174.488 1.00 60.21  ? 85  ASP B N   1 
ATOM   3414 C CA  . ASP B 1 88  ? 137.056 47.447  175.825 1.00 51.50  ? 85  ASP B CA  1 
ATOM   3415 C C   . ASP B 1 88  ? 135.601 47.868  175.993 1.00 55.12  ? 85  ASP B C   1 
ATOM   3416 O O   . ASP B 1 88  ? 135.008 48.509  175.119 1.00 59.62  ? 85  ASP B O   1 
ATOM   3417 C CB  . ASP B 1 88  ? 137.974 48.628  176.129 1.00 54.42  ? 85  ASP B CB  1 
ATOM   3418 C CG  . ASP B 1 88  ? 139.382 48.193  176.472 1.00 62.50  ? 85  ASP B CG  1 
ATOM   3419 O OD1 . ASP B 1 88  ? 139.707 46.995  176.275 1.00 66.21  ? 85  ASP B OD1 1 
ATOM   3420 O OD2 . ASP B 1 88  ? 140.146 49.026  177.002 1.00 63.52  ? 85  ASP B OD2 1 
ATOM   3421 N N   . LEU B 1 89  ? 135.033 47.520  177.141 1.00 55.94  ? 86  LEU B N   1 
ATOM   3422 C CA  . LEU B 1 89  ? 133.695 47.946  177.527 1.00 54.96  ? 86  LEU B CA  1 
ATOM   3423 C C   . LEU B 1 89  ? 133.776 49.251  178.316 1.00 55.27  ? 86  LEU B C   1 
ATOM   3424 O O   . LEU B 1 89  ? 134.603 49.381  179.224 1.00 56.57  ? 86  LEU B O   1 
ATOM   3425 C CB  . LEU B 1 89  ? 133.051 46.847  178.371 1.00 53.62  ? 86  LEU B CB  1 
ATOM   3426 C CG  . LEU B 1 89  ? 132.856 45.493  177.693 1.00 52.42  ? 86  LEU B CG  1 
ATOM   3427 C CD1 . LEU B 1 89  ? 132.520 44.401  178.702 1.00 50.15  ? 86  LEU B CD1 1 
ATOM   3428 C CD2 . LEU B 1 89  ? 131.746 45.614  176.668 1.00 51.50  ? 86  LEU B CD2 1 
ATOM   3429 N N   . VAL B 1 90  ? 132.951 50.232  177.952 1.00 52.48  ? 87  VAL B N   1 
ATOM   3430 C CA  . VAL B 1 90  ? 132.982 51.519  178.633 1.00 54.71  ? 87  VAL B CA  1 
ATOM   3431 C C   . VAL B 1 90  ? 131.559 51.918  178.966 1.00 57.45  ? 87  VAL B C   1 
ATOM   3432 O O   . VAL B 1 90  ? 130.596 51.465  178.345 1.00 57.07  ? 87  VAL B O   1 
ATOM   3433 C CB  . VAL B 1 90  ? 133.640 52.645  177.813 1.00 50.50  ? 87  VAL B CB  1 
ATOM   3434 C CG1 . VAL B 1 90  ? 135.015 52.231  177.369 1.00 54.37  ? 87  VAL B CG1 1 
ATOM   3435 C CG2 . VAL B 1 90  ? 132.751 53.064  176.657 1.00 49.31  ? 87  VAL B CG2 1 
ATOM   3436 N N   . GLN B 1 91  ? 131.441 52.800  179.947 1.00 55.09  ? 88  GLN B N   1 
ATOM   3437 C CA  . GLN B 1 91  ? 130.159 53.323  180.378 1.00 52.29  ? 88  GLN B CA  1 
ATOM   3438 C C   . GLN B 1 91  ? 130.205 54.840  180.315 1.00 54.40  ? 88  GLN B C   1 
ATOM   3439 O O   . GLN B 1 91  ? 131.169 55.456  180.777 1.00 59.71  ? 88  GLN B O   1 
ATOM   3440 C CB  . GLN B 1 91  ? 129.836 52.821  181.784 1.00 49.68  ? 88  GLN B CB  1 
ATOM   3441 C CG  . GLN B 1 91  ? 128.440 53.110  182.171 1.00 55.49  ? 88  GLN B CG  1 
ATOM   3442 C CD  . GLN B 1 91  ? 128.333 54.434  182.891 1.00 59.25  ? 88  GLN B CD  1 
ATOM   3443 O OE1 . GLN B 1 91  ? 129.109 54.720  183.823 1.00 59.00  ? 88  GLN B OE1 1 
ATOM   3444 N NE2 . GLN B 1 91  ? 127.413 55.278  182.433 1.00 51.92  ? 88  GLN B NE2 1 
ATOM   3445 N N   . GLY B 1 92  ? 129.181 55.438  179.730 1.00 50.97  ? 89  GLY B N   1 
ATOM   3446 C CA  . GLY B 1 92  ? 129.171 56.878  179.572 1.00 49.12  ? 89  GLY B CA  1 
ATOM   3447 C C   . GLY B 1 92  ? 127.854 57.290  178.969 1.00 52.67  ? 89  GLY B C   1 
ATOM   3448 O O   . GLY B 1 92  ? 126.975 56.460  178.708 1.00 55.14  ? 89  GLY B O   1 
ATOM   3449 N N   . PHE B 1 93  ? 127.738 58.580  178.703 1.00 47.98  ? 90  PHE B N   1 
ATOM   3450 C CA  . PHE B 1 93  ? 126.471 59.123  178.221 1.00 53.15  ? 90  PHE B CA  1 
ATOM   3451 C C   . PHE B 1 93  ? 126.373 59.042  176.687 1.00 54.51  ? 90  PHE B C   1 
ATOM   3452 O O   . PHE B 1 93  ? 126.320 60.038  175.960 1.00 52.92  ? 90  PHE B O   1 
ATOM   3453 C CB  . PHE B 1 93  ? 126.293 60.542  178.754 1.00 53.42  ? 90  PHE B CB  1 
ATOM   3454 C CG  . PHE B 1 93  ? 124.875 60.906  179.007 1.00 54.79  ? 90  PHE B CG  1 
ATOM   3455 C CD1 . PHE B 1 93  ? 124.105 60.165  179.892 1.00 55.64  ? 90  PHE B CD1 1 
ATOM   3456 C CD2 . PHE B 1 93  ? 124.304 61.995  178.369 1.00 56.29  ? 90  PHE B CD2 1 
ATOM   3457 C CE1 . PHE B 1 93  ? 122.772 60.492  180.118 1.00 55.03  ? 90  PHE B CE1 1 
ATOM   3458 C CE2 . PHE B 1 93  ? 122.983 62.331  178.590 1.00 57.85  ? 90  PHE B CE2 1 
ATOM   3459 C CZ  . PHE B 1 93  ? 122.215 61.576  179.470 1.00 55.56  ? 90  PHE B CZ  1 
ATOM   3460 N N   . GLY B 1 94  ? 126.353 57.798  176.197 1.00 55.52  ? 91  GLY B N   1 
ATOM   3461 C CA  . GLY B 1 94  ? 126.420 57.565  174.758 1.00 53.80  ? 91  GLY B CA  1 
ATOM   3462 C C   . GLY B 1 94  ? 125.169 57.993  174.011 1.00 54.37  ? 91  GLY B C   1 
ATOM   3463 O O   . GLY B 1 94  ? 125.251 58.563  172.924 1.00 54.82  ? 91  GLY B O   1 
ATOM   3464 N N   . GLY B 1 95  ? 124.002 57.779  174.598 1.00 56.26  ? 92  GLY B N   1 
ATOM   3465 C CA  . GLY B 1 95  ? 122.746 58.197  174.011 1.00 52.71  ? 92  GLY B CA  1 
ATOM   3466 C C   . GLY B 1 95  ? 122.004 57.038  173.380 1.00 51.20  ? 92  GLY B C   1 
ATOM   3467 O O   . GLY B 1 95  ? 122.492 55.910  173.309 1.00 55.97  ? 92  GLY B O   1 
ATOM   3468 N N   . TRP B 1 96  ? 120.781 57.336  172.923 1.00 53.45  ? 93  TRP B N   1 
ATOM   3469 C CA  . TRP B 1 96  ? 119.941 56.378  172.193 1.00 55.79  ? 93  TRP B CA  1 
ATOM   3470 C C   . TRP B 1 96  ? 120.409 56.293  170.731 1.00 59.51  ? 93  TRP B C   1 
ATOM   3471 O O   . TRP B 1 96  ? 119.744 56.744  169.796 1.00 58.76  ? 93  TRP B O   1 
ATOM   3472 C CB  . TRP B 1 96  ? 118.474 56.793  172.250 1.00 57.29  ? 93  TRP B CB  1 
ATOM   3473 C CG  . TRP B 1 96  ? 117.807 56.749  173.572 1.00 60.26  ? 93  TRP B CG  1 
ATOM   3474 C CD1 . TRP B 1 96  ? 118.313 56.260  174.727 1.00 64.02  ? 93  TRP B CD1 1 
ATOM   3475 C CD2 . TRP B 1 96  ? 116.482 57.203  173.878 1.00 62.72  ? 93  TRP B CD2 1 
ATOM   3476 N NE1 . TRP B 1 96  ? 117.392 56.377  175.749 1.00 61.28  ? 93  TRP B NE1 1 
ATOM   3477 C CE2 . TRP B 1 96  ? 116.259 56.959  175.247 1.00 61.80  ? 93  TRP B CE2 1 
ATOM   3478 C CE3 . TRP B 1 96  ? 115.467 57.785  173.131 1.00 60.41  ? 93  TRP B CE3 1 
ATOM   3479 C CZ2 . TRP B 1 96  ? 115.064 57.275  175.875 1.00 58.19  ? 93  TRP B CZ2 1 
ATOM   3480 C CZ3 . TRP B 1 96  ? 114.287 58.101  173.762 1.00 65.45  ? 93  TRP B CZ3 1 
ATOM   3481 C CH2 . TRP B 1 96  ? 114.094 57.847  175.118 1.00 61.51  ? 93  TRP B CH2 1 
ATOM   3482 N N   . ARG B 1 97  ? 121.588 55.694  170.543 1.00 59.85  ? 94  ARG B N   1 
ATOM   3483 C CA  . ARG B 1 97  ? 122.221 55.543  169.237 1.00 59.13  ? 94  ARG B CA  1 
ATOM   3484 C C   . ARG B 1 97  ? 122.858 54.162  169.151 1.00 63.26  ? 94  ARG B C   1 
ATOM   3485 O O   . ARG B 1 97  ? 123.300 53.610  170.167 1.00 63.18  ? 94  ARG B O   1 
ATOM   3486 C CB  . ARG B 1 97  ? 123.306 56.610  169.010 1.00 55.64  ? 94  ARG B CB  1 
ATOM   3487 C CG  . ARG B 1 97  ? 122.799 58.011  169.163 1.00 56.92  ? 94  ARG B CG  1 
ATOM   3488 C CD  . ARG B 1 97  ? 123.843 59.047  168.858 1.00 57.64  ? 94  ARG B CD  1 
ATOM   3489 N NE  . ARG B 1 97  ? 124.918 59.130  169.835 1.00 55.22  ? 94  ARG B NE  1 
ATOM   3490 C CZ  . ARG B 1 97  ? 125.862 60.058  169.792 1.00 57.06  ? 94  ARG B CZ  1 
ATOM   3491 N NH1 . ARG B 1 97  ? 125.881 60.971  168.837 1.00 66.11  ? 94  ARG B NH1 1 
ATOM   3492 N NH2 . ARG B 1 97  ? 126.787 60.095  170.745 1.00 53.65  ? 94  ARG B NH2 1 
ATOM   3493 N N   . THR B 1 98  ? 122.904 53.598  167.937 1.00 56.07  ? 95  THR B N   1 
ATOM   3494 C CA  . THR B 1 98  ? 123.520 52.282  167.783 1.00 53.86  ? 95  THR B CA  1 
ATOM   3495 C C   . THR B 1 98  ? 125.031 52.369  167.719 1.00 56.91  ? 95  THR B C   1 
ATOM   3496 O O   . THR B 1 98  ? 125.727 51.484  168.225 1.00 63.90  ? 95  THR B O   1 
ATOM   3497 C CB  . THR B 1 98  ? 123.004 51.571  166.554 1.00 57.58  ? 95  THR B CB  1 
ATOM   3498 O OG1 . THR B 1 98  ? 123.545 52.204  165.388 1.00 64.93  ? 95  THR B OG1 1 
ATOM   3499 C CG2 . THR B 1 98  ? 121.495 51.632  166.538 1.00 62.71  ? 95  THR B CG2 1 
ATOM   3500 N N   . HIS B 1 99  ? 125.559 53.386  167.057 1.00 55.33  ? 96  HIS B N   1 
ATOM   3501 C CA  . HIS B 1 99  ? 126.997 53.565  166.984 1.00 57.44  ? 96  HIS B CA  1 
ATOM   3502 C C   . HIS B 1 99  ? 127.287 55.050  167.122 1.00 56.59  ? 96  HIS B C   1 
ATOM   3503 O O   . HIS B 1 99  ? 126.423 55.892  166.875 1.00 54.11  ? 96  HIS B O   1 
ATOM   3504 C CB  . HIS B 1 99  ? 127.577 52.998  165.677 1.00 57.12  ? 96  HIS B CB  1 
ATOM   3505 C CG  . HIS B 1 99  ? 127.262 51.550  165.441 1.00 54.13  ? 96  HIS B CG  1 
ATOM   3506 N ND1 . HIS B 1 99  ? 126.006 51.105  165.088 1.00 55.34  ? 96  HIS B ND1 1 
ATOM   3507 C CD2 . HIS B 1 99  ? 128.054 50.450  165.465 1.00 55.65  ? 96  HIS B CD2 1 
ATOM   3508 C CE1 . HIS B 1 99  ? 126.030 49.792  164.934 1.00 57.43  ? 96  HIS B CE1 1 
ATOM   3509 N NE2 . HIS B 1 99  ? 127.262 49.369  165.155 1.00 56.22  ? 96  HIS B NE2 1 
ATOM   3510 N N   . LEU B 1 100 ? 128.501 55.358  167.578 1.00 58.51  ? 97  LEU B N   1 
ATOM   3511 C CA  . LEU B 1 100 ? 128.896 56.737  167.834 1.00 58.84  ? 97  LEU B CA  1 
ATOM   3512 C C   . LEU B 1 100 ? 130.415 56.836  167.790 1.00 58.77  ? 97  LEU B C   1 
ATOM   3513 O O   . LEU B 1 100 ? 131.126 55.834  167.888 1.00 60.56  ? 97  LEU B O   1 
ATOM   3514 C CB  . LEU B 1 100 ? 128.368 57.241  169.192 1.00 62.65  ? 97  LEU B CB  1 
ATOM   3515 C CG  . LEU B 1 100 ? 128.801 56.603  170.532 1.00 63.20  ? 97  LEU B CG  1 
ATOM   3516 C CD1 . LEU B 1 100 ? 129.838 57.475  171.257 1.00 64.14  ? 97  LEU B CD1 1 
ATOM   3517 C CD2 . LEU B 1 100 ? 127.632 56.325  171.463 1.00 57.27  ? 97  LEU B CD2 1 
ATOM   3518 N N   . VAL B 1 101 ? 130.904 58.062  167.644 1.00 60.17  ? 98  VAL B N   1 
ATOM   3519 C CA  . VAL B 1 101 ? 132.323 58.360  167.791 1.00 63.43  ? 98  VAL B CA  1 
ATOM   3520 C C   . VAL B 1 101 ? 132.499 59.341  168.950 1.00 58.60  ? 98  VAL B C   1 
ATOM   3521 O O   . VAL B 1 101 ? 131.717 60.286  169.101 1.00 58.99  ? 98  VAL B O   1 
ATOM   3522 C CB  . VAL B 1 101 ? 132.923 58.912  166.480 1.00 59.50  ? 98  VAL B CB  1 
ATOM   3523 C CG1 . VAL B 1 101 ? 134.368 59.312  166.675 1.00 57.90  ? 98  VAL B CG1 1 
ATOM   3524 C CG2 . VAL B 1 101 ? 132.841 57.857  165.409 1.00 62.38  ? 98  VAL B CG2 1 
ATOM   3525 N N   . SER B 1 102 ? 133.479 59.077  169.811 1.00 55.83  ? 99  SER B N   1 
ATOM   3526 C CA  . SER B 1 102 ? 133.720 59.960  170.946 1.00 65.47  ? 99  SER B CA  1 
ATOM   3527 C C   . SER B 1 102 ? 135.176 59.885  171.369 1.00 67.14  ? 99  SER B C   1 
ATOM   3528 O O   . SER B 1 102 ? 135.844 58.858  171.204 1.00 64.61  ? 99  SER B O   1 
ATOM   3529 C CB  . SER B 1 102 ? 132.829 59.636  172.161 1.00 66.65  ? 99  SER B CB  1 
ATOM   3530 O OG  . SER B 1 102 ? 133.110 60.505  173.249 1.00 58.40  ? 99  SER B OG  1 
ATOM   3531 N N   . ASP B 1 103 ? 135.652 60.998  171.913 1.00 68.41  ? 100 ASP B N   1 
ATOM   3532 C CA  . ASP B 1 103 ? 136.942 61.081  172.578 1.00 69.82  ? 100 ASP B CA  1 
ATOM   3533 C C   . ASP B 1 103 ? 136.876 60.618  174.021 1.00 69.17  ? 100 ASP B C   1 
ATOM   3534 O O   . ASP B 1 103 ? 137.906 60.609  174.701 1.00 66.75  ? 100 ASP B O   1 
ATOM   3535 C CB  . ASP B 1 103 ? 137.422 62.523  172.542 1.00 73.17  ? 100 ASP B CB  1 
ATOM   3536 C CG  . ASP B 1 103 ? 136.346 63.481  173.017 1.00 80.49  ? 100 ASP B CG  1 
ATOM   3537 O OD1 . ASP B 1 103 ? 135.150 63.156  172.808 1.00 81.35  ? 100 ASP B OD1 1 
ATOM   3538 O OD2 . ASP B 1 103 ? 136.675 64.525  173.627 1.00 83.53  ? 100 ASP B OD2 1 
ATOM   3539 N N   . GLY B 1 104 ? 135.689 60.249  174.496 1.00 69.13  ? 101 GLY B N   1 
ATOM   3540 C CA  . GLY B 1 104 ? 135.497 59.785  175.852 1.00 66.51  ? 101 GLY B CA  1 
ATOM   3541 C C   . GLY B 1 104 ? 135.721 60.832  176.915 1.00 69.80  ? 101 GLY B C   1 
ATOM   3542 O O   . GLY B 1 104 ? 135.716 60.494  178.104 1.00 67.07  ? 101 GLY B O   1 
ATOM   3543 N N   . LYS B 1 105 ? 135.909 62.105  176.526 1.00 72.32  ? 102 LYS B N   1 
ATOM   3544 C CA  . LYS B 1 105 ? 136.285 63.157  177.461 1.00 72.56  ? 102 LYS B CA  1 
ATOM   3545 C C   . LYS B 1 105 ? 135.067 63.796  178.112 1.00 64.15  ? 102 LYS B C   1 
ATOM   3546 O O   . LYS B 1 105 ? 133.937 63.660  177.630 1.00 62.76  ? 102 LYS B O   1 
ATOM   3547 C CB  . LYS B 1 105 ? 137.121 64.219  176.740 1.00 76.61  ? 102 LYS B CB  1 
ATOM   3548 C CG  . LYS B 1 105 ? 138.558 63.802  176.475 1.00 71.99  ? 102 LYS B CG  1 
ATOM   3549 C CD  . LYS B 1 105 ? 139.302 64.824  175.651 1.00 73.46  ? 102 LYS B CD  1 
ATOM   3550 C CE  . LYS B 1 105 ? 140.688 64.311  175.342 1.00 79.05  ? 102 LYS B CE  1 
ATOM   3551 N NZ  . LYS B 1 105 ? 141.321 63.782  176.581 1.00 89.54  ? 102 LYS B NZ  1 
ATOM   3552 N N   . PRO B 1 106 ? 135.259 64.493  179.222 1.00 60.61  ? 103 PRO B N   1 
ATOM   3553 C CA  . PRO B 1 106 ? 134.120 65.164  179.846 1.00 62.85  ? 103 PRO B CA  1 
ATOM   3554 C C   . PRO B 1 106 ? 133.518 66.214  178.939 1.00 59.86  ? 103 PRO B C   1 
ATOM   3555 O O   . PRO B 1 106 ? 134.072 67.306  178.801 1.00 60.20  ? 103 PRO B O   1 
ATOM   3556 C CB  . PRO B 1 106 ? 134.728 65.780  181.110 1.00 53.43  ? 103 PRO B CB  1 
ATOM   3557 C CG  . PRO B 1 106 ? 135.887 64.910  181.407 1.00 50.75  ? 103 PRO B CG  1 
ATOM   3558 C CD  . PRO B 1 106 ? 136.454 64.544  180.077 1.00 60.50  ? 103 PRO B CD  1 
ATOM   3559 N N   . LYS B 1 107 ? 132.345 65.909  178.386 1.00 61.69  ? 104 LYS B N   1 
ATOM   3560 C CA  . LYS B 1 107 ? 131.590 66.874  177.602 1.00 65.66  ? 104 LYS B CA  1 
ATOM   3561 C C   . LYS B 1 107 ? 130.762 67.749  178.535 1.00 69.41  ? 104 LYS B C   1 
ATOM   3562 O O   . LYS B 1 107 ? 130.382 67.337  179.634 1.00 67.21  ? 104 LYS B O   1 
ATOM   3563 C CB  . LYS B 1 107 ? 130.679 66.162  176.584 1.00 62.19  ? 104 LYS B CB  1 
ATOM   3564 C CG  . LYS B 1 107 ? 131.404 65.499  175.377 1.00 68.31  ? 104 LYS B CG  1 
ATOM   3565 C CD  . LYS B 1 107 ? 130.405 64.965  174.300 1.00 82.93  ? 104 LYS B CD  1 
ATOM   3566 C CE  . LYS B 1 107 ? 131.014 64.832  172.880 1.00 74.68  ? 104 LYS B CE  1 
ATOM   3567 N NZ  . LYS B 1 107 ? 131.887 63.630  172.702 1.00 66.89  ? 104 LYS B NZ  1 
ATOM   3568 N N   . LEU B 1 108 ? 130.492 68.972  178.091 1.00 74.04  ? 105 LEU B N   1 
ATOM   3569 C CA  . LEU B 1 108 ? 129.701 69.927  178.850 1.00 76.66  ? 105 LEU B CA  1 
ATOM   3570 C C   . LEU B 1 108 ? 128.309 70.032  178.244 1.00 76.47  ? 105 LEU B C   1 
ATOM   3571 O O   . LEU B 1 108 ? 128.156 69.990  177.025 1.00 75.09  ? 105 LEU B O   1 
ATOM   3572 C CB  . LEU B 1 108 ? 130.397 71.288  178.874 1.00 77.19  ? 105 LEU B CB  1 
ATOM   3573 C CG  . LEU B 1 108 ? 129.614 72.490  179.383 1.00 84.90  ? 105 LEU B CG  1 
ATOM   3574 C CD1 . LEU B 1 108 ? 129.169 72.279  180.806 1.00 83.13  ? 105 LEU B CD1 1 
ATOM   3575 C CD2 . LEU B 1 108 ? 130.556 73.645  179.327 1.00 82.30  ? 105 LEU B CD2 1 
ATOM   3576 N N   . TRP B 1 109 ? 127.293 70.141  179.104 1.00 78.12  ? 106 TRP B N   1 
ATOM   3577 C CA  . TRP B 1 109 ? 125.896 70.240  178.671 1.00 81.11  ? 106 TRP B CA  1 
ATOM   3578 C C   . TRP B 1 109 ? 125.519 71.715  178.647 1.00 89.58  ? 106 TRP B C   1 
ATOM   3579 O O   . TRP B 1 109 ? 124.954 72.266  179.600 1.00 89.46  ? 106 TRP B O   1 
ATOM   3580 C CB  . TRP B 1 109 ? 124.984 69.425  179.581 1.00 77.72  ? 106 TRP B CB  1 
ATOM   3581 C CG  . TRP B 1 109 ? 123.525 69.295  179.158 1.00 80.57  ? 106 TRP B CG  1 
ATOM   3582 C CD1 . TRP B 1 109 ? 122.429 69.590  179.920 1.00 83.34  ? 106 TRP B CD1 1 
ATOM   3583 C CD2 . TRP B 1 109 ? 123.013 68.791  177.911 1.00 82.38  ? 106 TRP B CD2 1 
ATOM   3584 N NE1 . TRP B 1 109 ? 121.270 69.314  179.228 1.00 82.26  ? 106 TRP B NE1 1 
ATOM   3585 C CE2 . TRP B 1 109 ? 121.599 68.825  177.992 1.00 84.04  ? 106 TRP B CE2 1 
ATOM   3586 C CE3 . TRP B 1 109 ? 123.607 68.322  176.735 1.00 78.27  ? 106 TRP B CE3 1 
ATOM   3587 C CZ2 . TRP B 1 109 ? 120.776 68.416  176.940 1.00 80.66  ? 106 TRP B CZ2 1 
ATOM   3588 C CZ3 . TRP B 1 109 ? 122.788 67.912  175.698 1.00 78.27  ? 106 TRP B CZ3 1 
ATOM   3589 C CH2 . TRP B 1 109 ? 121.386 67.963  175.808 1.00 79.04  ? 106 TRP B CH2 1 
ATOM   3590 N N   . GLN B 1 110 ? 125.880 72.364  177.536 1.00 95.63  ? 107 GLN B N   1 
ATOM   3591 C CA  . GLN B 1 110 ? 125.660 73.801  177.390 1.00 104.68 ? 107 GLN B CA  1 
ATOM   3592 C C   . GLN B 1 110 ? 124.179 74.140  177.522 1.00 107.20 ? 107 GLN B C   1 
ATOM   3593 O O   . GLN B 1 110 ? 123.792 75.028  178.297 1.00 103.79 ? 107 GLN B O   1 
ATOM   3594 C CB  . GLN B 1 110 ? 126.198 74.278  176.033 1.00 99.85  ? 107 GLN B CB  1 
ATOM   3595 C CG  . GLN B 1 110 ? 127.077 75.514  176.123 1.00 104.28 ? 107 GLN B CG  1 
ATOM   3596 C CD  . GLN B 1 110 ? 128.242 75.303  177.074 1.00 110.69 ? 107 GLN B CD  1 
ATOM   3597 O OE1 . GLN B 1 110 ? 129.071 74.421  176.856 1.00 111.21 ? 107 GLN B OE1 1 
ATOM   3598 N NE2 . GLN B 1 110 ? 128.300 76.099  178.143 1.00 103.53 ? 107 GLN B NE2 1 
ATOM   3599 N N   . THR B 1 111 ? 123.336 73.391  176.807 1.00 107.09 ? 108 THR B N   1 
ATOM   3600 C CA  . THR B 1 111 ? 121.902 73.620  176.678 1.00 105.71 ? 108 THR B CA  1 
ATOM   3601 C C   . THR B 1 111 ? 121.119 73.258  177.958 1.00 96.40  ? 108 THR B C   1 
ATOM   3602 O O   . THR B 1 111 ? 119.921 72.959  177.903 1.00 94.96  ? 108 THR B O   1 
ATOM   3603 C CB  . THR B 1 111 ? 121.435 72.868  175.393 1.00 97.96  ? 108 THR B CB  1 
ATOM   3604 O OG1 . THR B 1 111 ? 120.031 73.046  175.137 1.00 101.85 ? 108 THR B OG1 1 
ATOM   3605 C CG2 . THR B 1 111 ? 121.806 71.367  175.439 1.00 89.65  ? 108 THR B CG2 1 
ATOM   3606 N N   . GLY B 1 112 ? 121.770 73.331  179.125 1.00 91.96  ? 109 GLY B N   1 
ATOM   3607 C CA  . GLY B 1 112 ? 121.156 72.958  180.390 1.00 93.84  ? 109 GLY B CA  1 
ATOM   3608 C C   . GLY B 1 112 ? 120.790 74.150  181.255 1.00 95.43  ? 109 GLY B C   1 
ATOM   3609 O O   . GLY B 1 112 ? 121.416 75.208  181.170 1.00 99.21  ? 109 GLY B O   1 
ATOM   3610 N N   . THR B 1 113 ? 119.769 73.962  182.104 1.00 95.70  ? 110 THR B N   1 
ATOM   3611 C CA  . THR B 1 113 ? 119.417 74.960  183.126 1.00 104.83 ? 110 THR B CA  1 
ATOM   3612 C C   . THR B 1 113 ? 120.619 75.344  183.983 1.00 103.63 ? 110 THR B C   1 
ATOM   3613 O O   . THR B 1 113 ? 120.825 76.521  184.319 1.00 97.87  ? 110 THR B O   1 
ATOM   3614 C CB  . THR B 1 113 ? 118.309 74.409  184.036 1.00 100.78 ? 110 THR B CB  1 
ATOM   3615 O OG1 . THR B 1 113 ? 117.128 74.133  183.271 1.00 93.49  ? 110 THR B OG1 1 
ATOM   3616 C CG2 . THR B 1 113 ? 118.010 75.363  185.227 1.00 96.74  ? 110 THR B CG2 1 
ATOM   3617 N N   . PHE B 1 114 ? 121.393 74.348  184.382 1.00 102.62 ? 111 PHE B N   1 
ATOM   3618 C CA  . PHE B 1 114 ? 122.616 74.515  185.115 1.00 97.94  ? 111 PHE B CA  1 
ATOM   3619 C C   . PHE B 1 114 ? 123.741 73.956  184.255 1.00 93.95  ? 111 PHE B C   1 
ATOM   3620 O O   . PHE B 1 114 ? 123.590 72.854  183.699 1.00 91.95  ? 111 PHE B O   1 
ATOM   3621 C CB  . PHE B 1 114 ? 122.528 73.788  186.479 1.00 85.98  ? 111 PHE B CB  1 
ATOM   3622 C CG  . PHE B 1 114 ? 121.714 72.494  186.462 1.00 89.03  ? 111 PHE B CG  1 
ATOM   3623 C CD1 . PHE B 1 114 ? 120.339 72.506  186.692 1.00 88.62  ? 111 PHE B CD1 1 
ATOM   3624 C CD2 . PHE B 1 114 ? 122.334 71.259  186.248 1.00 89.55  ? 111 PHE B CD2 1 
ATOM   3625 C CE1 . PHE B 1 114 ? 119.595 71.313  186.696 1.00 92.75  ? 111 PHE B CE1 1 
ATOM   3626 C CE2 . PHE B 1 114 ? 121.595 70.055  186.254 1.00 86.61  ? 111 PHE B CE2 1 
ATOM   3627 C CZ  . PHE B 1 114 ? 120.227 70.086  186.479 1.00 89.59  ? 111 PHE B CZ  1 
ATOM   3628 N N   . PRO B 1 115 ? 124.819 74.709  184.025 1.00 96.09  ? 112 PRO B N   1 
ATOM   3629 C CA  . PRO B 1 115 ? 125.970 74.136  183.317 1.00 93.23  ? 112 PRO B CA  1 
ATOM   3630 C C   . PRO B 1 115 ? 126.410 72.866  184.028 1.00 83.51  ? 112 PRO B C   1 
ATOM   3631 O O   . PRO B 1 115 ? 126.735 72.873  185.210 1.00 84.65  ? 112 PRO B O   1 
ATOM   3632 C CB  . PRO B 1 115 ? 127.030 75.244  183.402 1.00 95.55  ? 112 PRO B CB  1 
ATOM   3633 C CG  . PRO B 1 115 ? 126.637 76.055  184.620 1.00 96.59  ? 112 PRO B CG  1 
ATOM   3634 C CD  . PRO B 1 115 ? 125.121 76.036  184.589 1.00 98.45  ? 112 PRO B CD  1 
ATOM   3635 N N   . MET B 1 116 ? 126.482 71.783  183.282 1.00 80.52  ? 113 MET B N   1 
ATOM   3636 C CA  . MET B 1 116 ? 126.710 70.469  183.852 1.00 68.70  ? 113 MET B CA  1 
ATOM   3637 C C   . MET B 1 116 ? 127.728 69.744  182.993 1.00 73.57  ? 113 MET B C   1 
ATOM   3638 O O   . MET B 1 116 ? 127.646 69.766  181.761 1.00 79.15  ? 113 MET B O   1 
ATOM   3639 C CB  . MET B 1 116 ? 125.388 69.705  183.930 1.00 64.76  ? 113 MET B CB  1 
ATOM   3640 C CG  . MET B 1 116 ? 125.495 68.238  183.638 1.00 64.90  ? 113 MET B CG  1 
ATOM   3641 S SD  . MET B 1 116 ? 123.907 67.488  183.949 1.00 76.86  ? 113 MET B SD  1 
ATOM   3642 C CE  . MET B 1 116 ? 122.842 68.707  183.194 1.00 72.22  ? 113 MET B CE  1 
ATOM   3643 N N   . VAL B 1 117 ? 128.701 69.133  183.636 1.00 65.02  ? 114 VAL B N   1 
ATOM   3644 C CA  . VAL B 1 117 ? 129.751 68.408  182.940 1.00 65.39  ? 114 VAL B CA  1 
ATOM   3645 C C   . VAL B 1 117 ? 129.426 66.919  182.950 1.00 64.56  ? 114 VAL B C   1 
ATOM   3646 O O   . VAL B 1 117 ? 129.416 66.285  184.012 1.00 62.91  ? 114 VAL B O   1 
ATOM   3647 C CB  . VAL B 1 117 ? 131.110 68.689  183.582 1.00 58.23  ? 114 VAL B CB  1 
ATOM   3648 C CG1 . VAL B 1 117 ? 132.164 67.868  182.924 1.00 63.78  ? 114 VAL B CG1 1 
ATOM   3649 C CG2 . VAL B 1 117 ? 131.411 70.161  183.464 1.00 62.83  ? 114 VAL B CG2 1 
ATOM   3650 N N   . PHE B 1 118 ? 129.158 66.347  181.775 1.00 59.37  ? 115 PHE B N   1 
ATOM   3651 C CA  . PHE B 1 118 ? 129.024 64.900  181.699 1.00 56.52  ? 115 PHE B CA  1 
ATOM   3652 C C   . PHE B 1 118 ? 130.375 64.231  181.939 1.00 59.92  ? 115 PHE B C   1 
ATOM   3653 O O   . PHE B 1 118 ? 131.398 64.689  181.426 1.00 61.31  ? 115 PHE B O   1 
ATOM   3654 C CB  . PHE B 1 118 ? 128.488 64.483  180.356 1.00 55.35  ? 115 PHE B CB  1 
ATOM   3655 C CG  . PHE B 1 118 ? 127.052 64.770  180.195 1.00 65.63  ? 115 PHE B CG  1 
ATOM   3656 C CD1 . PHE B 1 118 ? 126.195 64.628  181.267 1.00 57.04  ? 115 PHE B CD1 1 
ATOM   3657 C CD2 . PHE B 1 118 ? 126.548 65.207  178.975 1.00 72.25  ? 115 PHE B CD2 1 
ATOM   3658 C CE1 . PHE B 1 118 ? 124.861 64.890  181.131 1.00 58.83  ? 115 PHE B CE1 1 
ATOM   3659 C CE2 . PHE B 1 118 ? 125.205 65.477  178.831 1.00 70.43  ? 115 PHE B CE2 1 
ATOM   3660 C CZ  . PHE B 1 118 ? 124.358 65.316  179.913 1.00 65.64  ? 115 PHE B CZ  1 
ATOM   3661 N N   . PRO B 1 119 ? 130.409 63.139  182.688 1.00 57.56  ? 116 PRO B N   1 
ATOM   3662 C CA  . PRO B 1 119 ? 131.695 62.538  183.040 1.00 56.27  ? 116 PRO B CA  1 
ATOM   3663 C C   . PRO B 1 119 ? 132.335 61.845  181.853 1.00 57.30  ? 116 PRO B C   1 
ATOM   3664 O O   . PRO B 1 119 ? 131.660 61.343  180.948 1.00 55.19  ? 116 PRO B O   1 
ATOM   3665 C CB  . PRO B 1 119 ? 131.327 61.531  184.131 1.00 53.58  ? 116 PRO B CB  1 
ATOM   3666 C CG  . PRO B 1 119 ? 129.902 61.201  183.865 1.00 51.01  ? 116 PRO B CG  1 
ATOM   3667 C CD  . PRO B 1 119 ? 129.278 62.444  183.322 1.00 55.37  ? 116 PRO B CD  1 
ATOM   3668 N N   . ALA B 1 120 ? 133.663 61.844  181.861 1.00 57.25  ? 117 ALA B N   1 
ATOM   3669 C CA  . ALA B 1 120 ? 134.397 61.037  180.905 1.00 57.38  ? 117 ALA B CA  1 
ATOM   3670 C C   . ALA B 1 120 ? 133.993 59.579  181.058 1.00 54.34  ? 117 ALA B C   1 
ATOM   3671 O O   . ALA B 1 120 ? 133.547 59.147  182.120 1.00 53.83  ? 117 ALA B O   1 
ATOM   3672 C CB  . ALA B 1 120 ? 135.901 61.195  181.111 1.00 62.52  ? 117 ALA B CB  1 
ATOM   3673 N N   . TYR B 1 121 ? 134.098 58.830  179.969 1.00 53.69  ? 118 TYR B N   1 
ATOM   3674 C CA  . TYR B 1 121 ? 133.667 57.441  179.992 1.00 50.77  ? 118 TYR B CA  1 
ATOM   3675 C C   . TYR B 1 121 ? 134.508 56.677  181.013 1.00 47.44  ? 118 TYR B C   1 
ATOM   3676 O O   . TYR B 1 121 ? 135.639 57.059  181.321 1.00 49.06  ? 118 TYR B O   1 
ATOM   3677 C CB  . TYR B 1 121 ? 133.781 56.839  178.578 1.00 55.41  ? 118 TYR B CB  1 
ATOM   3678 C CG  . TYR B 1 121 ? 132.839 57.465  177.540 1.00 53.33  ? 118 TYR B CG  1 
ATOM   3679 C CD1 . TYR B 1 121 ? 132.016 58.530  177.879 1.00 58.20  ? 118 TYR B CD1 1 
ATOM   3680 C CD2 . TYR B 1 121 ? 132.789 57.005  176.229 1.00 48.37  ? 118 TYR B CD2 1 
ATOM   3681 C CE1 . TYR B 1 121 ? 131.163 59.108  176.967 1.00 56.35  ? 118 TYR B CE1 1 
ATOM   3682 C CE2 . TYR B 1 121 ? 131.934 57.582  175.300 1.00 51.30  ? 118 TYR B CE2 1 
ATOM   3683 C CZ  . TYR B 1 121 ? 131.117 58.639  175.683 1.00 58.39  ? 118 TYR B CZ  1 
ATOM   3684 O OH  . TYR B 1 121 ? 130.239 59.262  174.811 1.00 63.81  ? 118 TYR B OH  1 
ATOM   3685 N N   . ARG B 1 122 ? 133.943 55.620  181.585 1.00 45.24  ? 119 ARG B N   1 
ATOM   3686 C CA  . ARG B 1 122 ? 134.704 54.788  182.510 1.00 47.48  ? 119 ARG B CA  1 
ATOM   3687 C C   . ARG B 1 122 ? 134.824 53.374  181.963 1.00 53.88  ? 119 ARG B C   1 
ATOM   3688 O O   . ARG B 1 122 ? 133.872 52.827  181.383 1.00 50.98  ? 119 ARG B O   1 
ATOM   3689 C CB  . ARG B 1 122 ? 134.085 54.771  183.910 1.00 45.57  ? 119 ARG B CB  1 
ATOM   3690 C CG  . ARG B 1 122 ? 132.814 53.985  184.098 1.00 51.28  ? 119 ARG B CG  1 
ATOM   3691 C CD  . ARG B 1 122 ? 132.223 54.257  185.474 1.00 50.99  ? 119 ARG B CD  1 
ATOM   3692 N NE  . ARG B 1 122 ? 130.899 53.673  185.641 1.00 50.90  ? 119 ARG B NE  1 
ATOM   3693 C CZ  . ARG B 1 122 ? 130.694 52.509  186.241 1.00 54.23  ? 119 ARG B CZ  1 
ATOM   3694 N NH1 . ARG B 1 122 ? 131.699 51.810  186.754 1.00 55.85  ? 119 ARG B NH1 1 
ATOM   3695 N NH2 . ARG B 1 122 ? 129.455 52.036  186.340 1.00 53.03  ? 119 ARG B NH2 1 
ATOM   3696 N N   . LYS B 1 123 ? 135.988 52.769  182.170 1.00 49.22  ? 120 LYS B N   1 
ATOM   3697 C CA  . LYS B 1 123 ? 136.194 51.446  181.622 1.00 51.70  ? 120 LYS B CA  1 
ATOM   3698 C C   . LYS B 1 123 ? 135.532 50.440  182.543 1.00 48.44  ? 120 LYS B C   1 
ATOM   3699 O O   . LYS B 1 123 ? 135.646 50.538  183.761 1.00 53.08  ? 120 LYS B O   1 
ATOM   3700 C CB  . LYS B 1 123 ? 137.691 51.164  181.469 1.00 52.33  ? 120 LYS B CB  1 
ATOM   3701 C CG  . LYS B 1 123 ? 138.022 49.791  180.880 1.00 53.90  ? 120 LYS B CG  1 
ATOM   3702 C CD  . LYS B 1 123 ? 139.507 49.586  180.775 1.00 48.37  ? 120 LYS B CD  1 
ATOM   3703 C CE  . LYS B 1 123 ? 139.856 48.141  180.720 1.00 45.59  ? 120 LYS B CE  1 
ATOM   3704 N NZ  . LYS B 1 123 ? 141.337 48.020  180.744 1.00 60.24  ? 120 LYS B NZ  1 
ATOM   3705 N N   . LEU B 1 124 ? 134.873 49.447  181.963 1.00 47.06  ? 121 LEU B N   1 
ATOM   3706 C CA  . LEU B 1 124 ? 134.264 48.384  182.743 1.00 48.48  ? 121 LEU B CA  1 
ATOM   3707 C C   . LEU B 1 124 ? 135.197 47.187  182.691 1.00 50.97  ? 121 LEU B C   1 
ATOM   3708 O O   . LEU B 1 124 ? 135.565 46.729  181.605 1.00 56.76  ? 121 LEU B O   1 
ATOM   3709 C CB  . LEU B 1 124 ? 132.880 48.025  182.211 1.00 46.78  ? 121 LEU B CB  1 
ATOM   3710 C CG  . LEU B 1 124 ? 131.875 49.170  182.128 1.00 47.75  ? 121 LEU B CG  1 
ATOM   3711 C CD1 . LEU B 1 124 ? 130.551 48.665  181.586 1.00 49.67  ? 121 LEU B CD1 1 
ATOM   3712 C CD2 . LEU B 1 124 ? 131.691 49.843  183.459 1.00 45.46  ? 121 LEU B CD2 1 
ATOM   3713 N N   . ASP B 1 125 ? 135.587 46.695  183.863 1.00 56.99  ? 122 ASP B N   1 
ATOM   3714 C CA  . ASP B 1 125 ? 136.451 45.529  183.993 1.00 57.98  ? 122 ASP B CA  1 
ATOM   3715 C C   . ASP B 1 125 ? 135.568 44.320  184.289 1.00 60.00  ? 122 ASP B C   1 
ATOM   3716 O O   . ASP B 1 125 ? 134.880 44.284  185.317 1.00 57.20  ? 122 ASP B O   1 
ATOM   3717 C CB  . ASP B 1 125 ? 137.497 45.756  185.084 1.00 67.01  ? 122 ASP B CB  1 
ATOM   3718 C CG  . ASP B 1 125 ? 138.555 44.672  185.118 1.00 77.15  ? 122 ASP B CG  1 
ATOM   3719 O OD1 . ASP B 1 125 ? 138.241 43.521  185.516 1.00 74.71  ? 122 ASP B OD1 1 
ATOM   3720 O OD2 . ASP B 1 125 ? 139.709 44.986  184.724 1.00 82.91  ? 122 ASP B OD2 1 
ATOM   3721 N N   . LEU B 1 126 ? 135.557 43.358  183.357 1.00 59.42  ? 123 LEU B N   1 
ATOM   3722 C CA  . LEU B 1 126 ? 134.596 42.265  183.396 1.00 53.78  ? 123 LEU B CA  1 
ATOM   3723 C C   . LEU B 1 126 ? 134.748 41.395  184.630 1.00 56.24  ? 123 LEU B C   1 
ATOM   3724 O O   . LEU B 1 126 ? 133.793 40.711  185.010 1.00 55.92  ? 123 LEU B O   1 
ATOM   3725 C CB  . LEU B 1 126 ? 134.731 41.412  182.139 1.00 49.08  ? 123 LEU B CB  1 
ATOM   3726 C CG  . LEU B 1 126 ? 133.783 41.779  180.997 1.00 45.42  ? 123 LEU B CG  1 
ATOM   3727 C CD1 . LEU B 1 126 ? 134.298 41.135  179.749 1.00 52.12  ? 123 LEU B CD1 1 
ATOM   3728 C CD2 . LEU B 1 126 ? 132.354 41.381  181.245 1.00 38.70  ? 123 LEU B CD2 1 
ATOM   3729 N N   . ARG B 1 127 ? 135.907 41.421  185.285 1.00 61.01  ? 124 ARG B N   1 
ATOM   3730 C CA  . ARG B 1 127 ? 136.065 40.617  186.491 1.00 58.65  ? 124 ARG B CA  1 
ATOM   3731 C C   . ARG B 1 127 ? 135.001 40.970  187.526 1.00 58.62  ? 124 ARG B C   1 
ATOM   3732 O O   . ARG B 1 127 ? 134.543 40.096  188.268 1.00 55.21  ? 124 ARG B O   1 
ATOM   3733 C CB  . ARG B 1 127 ? 137.467 40.819  187.064 1.00 61.94  ? 124 ARG B CB  1 
ATOM   3734 C CG  . ARG B 1 127 ? 137.517 41.791  188.242 1.00 72.55  ? 124 ARG B CG  1 
ATOM   3735 C CD  . ARG B 1 127 ? 138.920 41.951  188.814 1.00 83.80  ? 124 ARG B CD  1 
ATOM   3736 N NE  . ARG B 1 127 ? 139.745 42.805  187.966 1.00 87.17  ? 124 ARG B NE  1 
ATOM   3737 C CZ  . ARG B 1 127 ? 140.125 44.036  188.287 1.00 89.17  ? 124 ARG B CZ  1 
ATOM   3738 N NH1 . ARG B 1 127 ? 139.791 44.584  189.451 1.00 84.42  ? 124 ARG B NH1 1 
ATOM   3739 N NH2 . ARG B 1 127 ? 140.855 44.735  187.418 1.00 87.89  ? 124 ARG B NH2 1 
ATOM   3740 N N   . HIS B 1 128 ? 134.539 42.228  187.525 1.00 60.51  ? 125 HIS B N   1 
ATOM   3741 C CA  . HIS B 1 128 ? 133.641 42.762  188.540 1.00 55.54  ? 125 HIS B CA  1 
ATOM   3742 C C   . HIS B 1 128 ? 132.247 42.161  188.463 1.00 54.46  ? 125 HIS B C   1 
ATOM   3743 O O   . HIS B 1 128 ? 131.472 42.321  189.409 1.00 59.99  ? 125 HIS B O   1 
ATOM   3744 C CB  . HIS B 1 128 ? 133.523 44.286  188.417 1.00 55.93  ? 125 HIS B CB  1 
ATOM   3745 C CG  . HIS B 1 128 ? 134.729 45.051  188.880 1.00 60.06  ? 125 HIS B CG  1 
ATOM   3746 N ND1 . HIS B 1 128 ? 135.931 44.454  189.192 1.00 64.18  ? 125 HIS B ND1 1 
ATOM   3747 C CD2 . HIS B 1 128 ? 134.913 46.382  189.073 1.00 66.47  ? 125 HIS B CD2 1 
ATOM   3748 C CE1 . HIS B 1 128 ? 136.801 45.379  189.561 1.00 68.76  ? 125 HIS B CE1 1 
ATOM   3749 N NE2 . HIS B 1 128 ? 136.209 46.558  189.497 1.00 69.35  ? 125 HIS B NE2 1 
ATOM   3750 N N   . TYR B 1 129 ? 131.914 41.484  187.375 1.00 53.47  ? 126 TYR B N   1 
ATOM   3751 C CA  . TYR B 1 129 ? 130.557 41.075  187.058 1.00 52.06  ? 126 TYR B CA  1 
ATOM   3752 C C   . TYR B 1 129 ? 130.475 39.553  187.046 1.00 51.00  ? 126 TYR B C   1 
ATOM   3753 O O   . TYR B 1 129 ? 131.475 38.851  186.877 1.00 52.91  ? 126 TYR B O   1 
ATOM   3754 C CB  . TYR B 1 129 ? 130.122 41.701  185.701 1.00 54.52  ? 126 TYR B CB  1 
ATOM   3755 C CG  . TYR B 1 129 ? 130.352 43.207  185.701 1.00 55.90  ? 126 TYR B CG  1 
ATOM   3756 C CD1 . TYR B 1 129 ? 129.417 44.060  186.246 1.00 56.19  ? 126 TYR B CD1 1 
ATOM   3757 C CD2 . TYR B 1 129 ? 131.550 43.763  185.261 1.00 55.84  ? 126 TYR B CD2 1 
ATOM   3758 C CE1 . TYR B 1 129 ? 129.631 45.424  186.300 1.00 56.31  ? 126 TYR B CE1 1 
ATOM   3759 C CE2 . TYR B 1 129 ? 131.776 45.136  185.326 1.00 53.88  ? 126 TYR B CE2 1 
ATOM   3760 C CZ  . TYR B 1 129 ? 130.804 45.960  185.844 1.00 55.04  ? 126 TYR B CZ  1 
ATOM   3761 O OH  . TYR B 1 129 ? 130.976 47.331  185.937 1.00 60.38  ? 126 TYR B OH  1 
ATOM   3762 N N   . ASP B 1 130 ? 129.291 39.042  187.332 1.00 49.98  ? 127 ASP B N   1 
ATOM   3763 C CA  . ASP B 1 130 ? 129.069 37.609  187.262 1.00 54.08  ? 127 ASP B CA  1 
ATOM   3764 C C   . ASP B 1 130 ? 127.582 37.389  187.017 1.00 59.54  ? 127 ASP B C   1 
ATOM   3765 O O   . ASP B 1 130 ? 126.855 38.310  186.623 1.00 57.52  ? 127 ASP B O   1 
ATOM   3766 C CB  . ASP B 1 130 ? 129.589 36.888  188.524 1.00 56.28  ? 127 ASP B CB  1 
ATOM   3767 C CG  . ASP B 1 130 ? 128.988 37.441  189.840 1.00 63.78  ? 127 ASP B CG  1 
ATOM   3768 O OD1 . ASP B 1 130 ? 127.810 37.888  189.827 1.00 58.43  ? 127 ASP B OD1 1 
ATOM   3769 O OD2 . ASP B 1 130 ? 129.683 37.377  190.902 1.00 62.62  ? 127 ASP B OD2 1 
ATOM   3770 N N   . ASP B 1 131 ? 127.128 36.161  187.233 1.00 60.20  ? 128 ASP B N   1 
ATOM   3771 C CA  . ASP B 1 131 ? 125.763 35.820  186.871 1.00 60.51  ? 128 ASP B CA  1 
ATOM   3772 C C   . ASP B 1 131 ? 124.742 36.413  187.852 1.00 56.36  ? 128 ASP B C   1 
ATOM   3773 O O   . ASP B 1 131 ? 123.557 36.472  187.519 1.00 56.10  ? 128 ASP B O   1 
ATOM   3774 C CB  . ASP B 1 131 ? 125.663 34.292  186.768 1.00 59.96  ? 128 ASP B CB  1 
ATOM   3775 C CG  . ASP B 1 131 ? 126.697 33.696  185.785 1.00 68.59  ? 128 ASP B CG  1 
ATOM   3776 O OD1 . ASP B 1 131 ? 126.745 34.145  184.609 1.00 76.18  ? 128 ASP B OD1 1 
ATOM   3777 O OD2 . ASP B 1 131 ? 127.483 32.797  186.196 1.00 63.40  ? 128 ASP B OD2 1 
ATOM   3778 N N   . ALA B 1 132 ? 125.176 36.872  189.040 1.00 57.80  ? 129 ALA B N   1 
ATOM   3779 C CA  . ALA B 1 132 ? 124.326 37.574  190.007 1.00 55.10  ? 129 ALA B CA  1 
ATOM   3780 C C   . ALA B 1 132 ? 124.420 39.088  189.908 1.00 56.22  ? 129 ALA B C   1 
ATOM   3781 O O   . ALA B 1 132 ? 123.499 39.787  190.348 1.00 54.08  ? 129 ALA B O   1 
ATOM   3782 C CB  . ALA B 1 132 ? 124.680 37.176  191.448 1.00 53.04  ? 129 ALA B CB  1 
ATOM   3783 N N   . LEU B 1 133 ? 125.509 39.602  189.350 1.00 57.16  ? 130 LEU B N   1 
ATOM   3784 C CA  . LEU B 1 133 ? 125.721 41.034  189.160 1.00 54.20  ? 130 LEU B CA  1 
ATOM   3785 C C   . LEU B 1 133 ? 126.199 41.215  187.724 1.00 59.04  ? 130 LEU B C   1 
ATOM   3786 O O   . LEU B 1 133 ? 127.384 41.480  187.471 1.00 60.73  ? 130 LEU B O   1 
ATOM   3787 C CB  . LEU B 1 133 ? 126.730 41.550  190.184 1.00 53.19  ? 130 LEU B CB  1 
ATOM   3788 C CG  . LEU B 1 133 ? 126.828 43.018  190.547 1.00 50.61  ? 130 LEU B CG  1 
ATOM   3789 C CD1 . LEU B 1 133 ? 125.697 43.377  191.481 1.00 51.84  ? 130 LEU B CD1 1 
ATOM   3790 C CD2 . LEU B 1 133 ? 128.159 43.244  191.224 1.00 57.07  ? 130 LEU B CD2 1 
ATOM   3791 N N   . PRO B 1 134 ? 125.289 41.020  186.735 1.00 59.68  ? 131 PRO B N   1 
ATOM   3792 C CA  . PRO B 1 134 ? 125.703 40.938  185.325 1.00 56.53  ? 131 PRO B CA  1 
ATOM   3793 C C   . PRO B 1 134 ? 126.285 42.242  184.792 1.00 56.92  ? 131 PRO B C   1 
ATOM   3794 O O   . PRO B 1 134 ? 126.283 43.246  185.506 1.00 59.92  ? 131 PRO B O   1 
ATOM   3795 C CB  . PRO B 1 134 ? 124.399 40.558  184.611 1.00 59.10  ? 131 PRO B CB  1 
ATOM   3796 C CG  . PRO B 1 134 ? 123.305 41.020  185.525 1.00 54.91  ? 131 PRO B CG  1 
ATOM   3797 C CD  . PRO B 1 134 ? 123.835 40.809  186.894 1.00 57.95  ? 131 PRO B CD  1 
ATOM   3798 N N   . LEU B 1 135 ? 126.767 42.251  183.543 1.00 56.98  ? 132 LEU B N   1 
ATOM   3799 C CA  . LEU B 1 135 ? 127.355 43.463  182.974 1.00 53.53  ? 132 LEU B CA  1 
ATOM   3800 C C   . LEU B 1 135 ? 126.362 44.624  182.946 1.00 53.08  ? 132 LEU B C   1 
ATOM   3801 O O   . LEU B 1 135 ? 126.760 45.787  183.059 1.00 52.55  ? 132 LEU B O   1 
ATOM   3802 C CB  . LEU B 1 135 ? 127.864 43.172  181.562 1.00 51.19  ? 132 LEU B CB  1 
ATOM   3803 C CG  . LEU B 1 135 ? 128.454 44.337  180.769 1.00 52.15  ? 132 LEU B CG  1 
ATOM   3804 C CD1 . LEU B 1 135 ? 129.754 44.776  181.413 1.00 51.89  ? 132 LEU B CD1 1 
ATOM   3805 C CD2 . LEU B 1 135 ? 128.674 43.939  179.334 1.00 50.77  ? 132 LEU B CD2 1 
ATOM   3806 N N   . SER B 1 136 ? 125.074 44.335  182.779 1.00 54.41  ? 133 SER B N   1 
ATOM   3807 C CA  . SER B 1 136 ? 124.056 45.377  182.778 1.00 49.39  ? 133 SER B CA  1 
ATOM   3808 C C   . SER B 1 136 ? 123.938 46.088  184.119 1.00 53.99  ? 133 SER B C   1 
ATOM   3809 O O   . SER B 1 136 ? 123.277 47.129  184.196 1.00 57.54  ? 133 SER B O   1 
ATOM   3810 C CB  . SER B 1 136 ? 122.701 44.790  182.368 1.00 55.37  ? 133 SER B CB  1 
ATOM   3811 O OG  . SER B 1 136 ? 122.304 43.728  183.222 1.00 61.45  ? 133 SER B OG  1 
ATOM   3812 N N   . THR B 1 137 ? 124.529 45.559  185.184 1.00 53.53  ? 134 THR B N   1 
ATOM   3813 C CA  . THR B 1 137 ? 124.453 46.307  186.428 1.00 51.68  ? 134 THR B CA  1 
ATOM   3814 C C   . THR B 1 137 ? 125.233 47.616  186.378 1.00 46.48  ? 134 THR B C   1 
ATOM   3815 O O   . THR B 1 137 ? 124.993 48.483  187.218 1.00 51.37  ? 134 THR B O   1 
ATOM   3816 C CB  . THR B 1 137 ? 124.916 45.441  187.605 1.00 54.42  ? 134 THR B CB  1 
ATOM   3817 O OG1 . THR B 1 137 ? 126.279 45.034  187.424 1.00 54.31  ? 134 THR B OG1 1 
ATOM   3818 C CG2 . THR B 1 137 ? 124.041 44.215  187.713 1.00 52.81  ? 134 THR B CG2 1 
ATOM   3819 N N   . ALA B 1 138 ? 126.111 47.816  185.402 1.00 46.08  ? 135 ALA B N   1 
ATOM   3820 C CA  . ALA B 1 138 ? 126.799 49.101  185.316 1.00 48.96  ? 135 ALA B CA  1 
ATOM   3821 C C   . ALA B 1 138 ? 125.867 50.267  184.983 1.00 46.85  ? 135 ALA B C   1 
ATOM   3822 O O   . ALA B 1 138 ? 126.297 51.421  185.050 1.00 45.06  ? 135 ALA B O   1 
ATOM   3823 C CB  . ALA B 1 138 ? 127.928 49.026  184.289 1.00 50.94  ? 135 ALA B CB  1 
ATOM   3824 N N   . LEU B 1 139 ? 124.615 50.012  184.626 1.00 44.50  ? 136 LEU B N   1 
ATOM   3825 C CA  . LEU B 1 139 ? 123.645 51.086  184.487 1.00 50.59  ? 136 LEU B CA  1 
ATOM   3826 C C   . LEU B 1 139 ? 122.658 51.115  185.650 1.00 49.29  ? 136 LEU B C   1 
ATOM   3827 O O   . LEU B 1 139 ? 121.691 51.881  185.622 1.00 53.49  ? 136 LEU B O   1 
ATOM   3828 C CB  . LEU B 1 139 ? 122.902 50.962  183.151 1.00 53.47  ? 136 LEU B CB  1 
ATOM   3829 C CG  . LEU B 1 139 ? 123.668 51.129  181.830 1.00 51.26  ? 136 LEU B CG  1 
ATOM   3830 C CD1 . LEU B 1 139 ? 122.716 51.119  180.677 1.00 54.10  ? 136 LEU B CD1 1 
ATOM   3831 C CD2 . LEU B 1 139 ? 124.493 52.401  181.796 1.00 48.99  ? 136 LEU B CD2 1 
ATOM   3832 N N   . GLY B 1 140 ? 122.880 50.301  186.671 1.00 48.16  ? 137 GLY B N   1 
ATOM   3833 C CA  . GLY B 1 140 ? 121.960 50.224  187.789 1.00 50.23  ? 137 GLY B CA  1 
ATOM   3834 C C   . GLY B 1 140 ? 122.630 50.176  189.146 1.00 45.67  ? 137 GLY B C   1 
ATOM   3835 O O   . GLY B 1 140 ? 123.146 51.196  189.629 1.00 43.79  ? 137 GLY B O   1 
ATOM   3836 N N   . VAL B 1 141 ? 122.618 49.000  189.782 1.00 41.44  ? 138 VAL B N   1 
ATOM   3837 C CA  . VAL B 1 141 ? 123.144 48.928  191.140 1.00 50.27  ? 138 VAL B CA  1 
ATOM   3838 C C   . VAL B 1 141 ? 124.656 49.147  191.150 1.00 48.98  ? 138 VAL B C   1 
ATOM   3839 O O   . VAL B 1 141 ? 125.214 49.610  192.163 1.00 46.73  ? 138 VAL B O   1 
ATOM   3840 C CB  . VAL B 1 141 ? 122.750 47.588  191.808 1.00 47.76  ? 138 VAL B CB  1 
ATOM   3841 C CG1 . VAL B 1 141 ? 123.479 46.422  191.175 1.00 50.64  ? 138 VAL B CG1 1 
ATOM   3842 C CG2 . VAL B 1 141 ? 123.032 47.628  193.275 1.00 44.09  ? 138 VAL B CG2 1 
ATOM   3843 N N   . MET B 1 142 ? 125.320 48.886  190.018 1.00 44.66  ? 139 MET B N   1 
ATOM   3844 C CA  . MET B 1 142 ? 126.755 49.078  189.855 1.00 45.16  ? 139 MET B CA  1 
ATOM   3845 C C   . MET B 1 142 ? 127.075 50.245  188.923 1.00 43.33  ? 139 MET B C   1 
ATOM   3846 O O   . MET B 1 142 ? 128.112 50.253  188.245 1.00 47.14  ? 139 MET B O   1 
ATOM   3847 C CB  . MET B 1 142 ? 127.387 47.789  189.342 1.00 49.06  ? 139 MET B CB  1 
ATOM   3848 C CG  . MET B 1 142 ? 127.336 46.641  190.310 1.00 46.82  ? 139 MET B CG  1 
ATOM   3849 S SD  . MET B 1 142 ? 128.511 46.872  191.652 1.00 49.34  ? 139 MET B SD  1 
ATOM   3850 C CE  . MET B 1 142 ? 127.421 47.268  193.023 1.00 52.05  ? 139 MET B CE  1 
ATOM   3851 N N   . GLY B 1 143 ? 126.178 51.210  188.863 1.00 37.92  ? 140 GLY B N   1 
ATOM   3852 C CA  . GLY B 1 143 ? 126.397 52.428  188.102 1.00 41.80  ? 140 GLY B CA  1 
ATOM   3853 C C   . GLY B 1 143 ? 125.690 53.595  188.737 1.00 41.99  ? 140 GLY B C   1 
ATOM   3854 O O   . GLY B 1 143 ? 125.569 53.664  189.961 1.00 44.04  ? 140 GLY B O   1 
ATOM   3855 N N   . GLY B 1 144 ? 125.170 54.482  187.915 1.00 47.73  ? 141 GLY B N   1 
ATOM   3856 C CA  . GLY B 1 144 ? 124.596 55.728  188.351 1.00 41.64  ? 141 GLY B CA  1 
ATOM   3857 C C   . GLY B 1 144 ? 123.667 55.617  189.526 1.00 46.27  ? 141 GLY B C   1 
ATOM   3858 O O   . GLY B 1 144 ? 123.826 56.321  190.525 1.00 52.54  ? 141 GLY B O   1 
ATOM   3859 N N   . PRO B 1 145 ? 122.646 54.778  189.417 1.00 48.92  ? 142 PRO B N   1 
ATOM   3860 C CA  . PRO B 1 145 ? 121.665 54.692  190.509 1.00 56.32  ? 142 PRO B CA  1 
ATOM   3861 C C   . PRO B 1 145 ? 122.234 54.128  191.807 1.00 46.90  ? 142 PRO B C   1 
ATOM   3862 O O   . PRO B 1 145 ? 122.005 54.693  192.877 1.00 43.56  ? 142 PRO B O   1 
ATOM   3863 C CB  . PRO B 1 145 ? 120.568 53.804  189.913 1.00 52.26  ? 142 PRO B CB  1 
ATOM   3864 C CG  . PRO B 1 145 ? 120.710 53.977  188.451 1.00 48.85  ? 142 PRO B CG  1 
ATOM   3865 C CD  . PRO B 1 145 ? 122.178 54.063  188.226 1.00 44.50  ? 142 PRO B CD  1 
ATOM   3866 N N   . GLY B 1 146 ? 122.985 53.030  191.715 1.00 46.22  ? 143 GLY B N   1 
ATOM   3867 C CA  . GLY B 1 146 ? 123.627 52.481  192.900 1.00 45.41  ? 143 GLY B CA  1 
ATOM   3868 C C   . GLY B 1 146 ? 124.599 53.452  193.539 1.00 41.78  ? 143 GLY B C   1 
ATOM   3869 O O   . GLY B 1 146 ? 124.737 53.493  194.755 1.00 40.42  ? 143 GLY B O   1 
ATOM   3870 N N   . MET B 1 147 ? 125.306 54.227  192.724 1.00 43.72  ? 144 MET B N   1 
ATOM   3871 C CA  . MET B 1 147 ? 126.198 55.232  193.269 1.00 42.26  ? 144 MET B CA  1 
ATOM   3872 C C   . MET B 1 147 ? 125.416 56.301  193.992 1.00 45.19  ? 144 MET B C   1 
ATOM   3873 O O   . MET B 1 147 ? 125.849 56.770  195.046 1.00 49.36  ? 144 MET B O   1 
ATOM   3874 C CB  . MET B 1 147 ? 127.034 55.871  192.174 1.00 41.68  ? 144 MET B CB  1 
ATOM   3875 C CG  . MET B 1 147 ? 127.985 56.949  192.653 1.00 42.34  ? 144 MET B CG  1 
ATOM   3876 S SD  . MET B 1 147 ? 129.260 56.311  193.740 1.00 40.68  ? 144 MET B SD  1 
ATOM   3877 C CE  . MET B 1 147 ? 130.377 55.438  192.670 1.00 41.16  ? 144 MET B CE  1 
ATOM   3878 N N   . THR B 1 148 ? 124.256 56.691  193.455 1.00 47.19  ? 145 THR B N   1 
ATOM   3879 C CA  . THR B 1 148 ? 123.398 57.644  194.165 1.00 50.90  ? 145 THR B CA  1 
ATOM   3880 C C   . THR B 1 148 ? 123.012 57.121  195.547 1.00 50.57  ? 145 THR B C   1 
ATOM   3881 O O   . THR B 1 148 ? 123.293 57.756  196.572 1.00 51.03  ? 145 THR B O   1 
ATOM   3882 C CB  . THR B 1 148 ? 122.142 57.950  193.359 1.00 49.52  ? 145 THR B CB  1 
ATOM   3883 O OG1 . THR B 1 148 ? 122.509 58.425  192.055 1.00 55.49  ? 145 THR B OG1 1 
ATOM   3884 C CG2 . THR B 1 148 ? 121.323 59.006  194.090 1.00 43.00  ? 145 THR B CG2 1 
ATOM   3885 N N   . ALA B 1 149 ? 122.385 55.946  195.593 1.00 48.69  ? 146 ALA B N   1 
ATOM   3886 C CA  . ALA B 1 149 ? 121.912 55.385  196.853 1.00 46.04  ? 146 ALA B CA  1 
ATOM   3887 C C   . ALA B 1 149 ? 123.061 55.168  197.840 1.00 46.64  ? 146 ALA B C   1 
ATOM   3888 O O   . ALA B 1 149 ? 123.036 55.671  198.967 1.00 47.38  ? 146 ALA B O   1 
ATOM   3889 C CB  . ALA B 1 149 ? 121.175 54.082  196.565 1.00 49.54  ? 146 ALA B CB  1 
ATOM   3890 N N   . TRP B 1 150 ? 124.074 54.405  197.442 1.00 46.81  ? 147 TRP B N   1 
ATOM   3891 C CA  . TRP B 1 150 ? 125.206 54.172  198.333 1.00 46.47  ? 147 TRP B CA  1 
ATOM   3892 C C   . TRP B 1 150 ? 125.918 55.465  198.684 1.00 47.45  ? 147 TRP B C   1 
ATOM   3893 O O   . TRP B 1 150 ? 126.472 55.590  199.777 1.00 48.04  ? 147 TRP B O   1 
ATOM   3894 C CB  . TRP B 1 150 ? 126.184 53.191  197.707 1.00 50.11  ? 147 TRP B CB  1 
ATOM   3895 C CG  . TRP B 1 150 ? 127.466 52.990  198.472 1.00 50.52  ? 147 TRP B CG  1 
ATOM   3896 C CD1 . TRP B 1 150 ? 127.697 52.076  199.450 1.00 53.23  ? 147 TRP B CD1 1 
ATOM   3897 C CD2 . TRP B 1 150 ? 128.706 53.684  198.271 1.00 54.37  ? 147 TRP B CD2 1 
ATOM   3898 N NE1 . TRP B 1 150 ? 128.998 52.163  199.883 1.00 52.97  ? 147 TRP B NE1 1 
ATOM   3899 C CE2 . TRP B 1 150 ? 129.637 53.144  199.176 1.00 49.35  ? 147 TRP B CE2 1 
ATOM   3900 C CE3 . TRP B 1 150 ? 129.118 54.716  197.413 1.00 57.15  ? 147 TRP B CE3 1 
ATOM   3901 C CZ2 . TRP B 1 150 ? 130.944 53.601  199.261 1.00 48.79  ? 147 TRP B CZ2 1 
ATOM   3902 C CZ3 . TRP B 1 150 ? 130.426 55.173  197.502 1.00 52.26  ? 147 TRP B CZ3 1 
ATOM   3903 C CH2 . TRP B 1 150 ? 131.319 54.613  198.423 1.00 50.59  ? 147 TRP B CH2 1 
ATOM   3904 N N   . GLY B 1 151 ? 126.000 56.406  197.743 1.00 49.59  ? 148 GLY B N   1 
ATOM   3905 C CA  . GLY B 1 151 ? 126.661 57.665  198.051 1.00 47.47  ? 148 GLY B CA  1 
ATOM   3906 C C   . GLY B 1 151 ? 125.963 58.405  199.174 1.00 47.27  ? 148 GLY B C   1 
ATOM   3907 O O   . GLY B 1 151 ? 126.586 58.804  200.160 1.00 44.27  ? 148 GLY B O   1 
ATOM   3908 N N   . THR B 1 152 ? 124.641 58.534  199.070 1.00 47.30  ? 149 THR B N   1 
ATOM   3909 C CA  . THR B 1 152 ? 123.884 59.254  200.086 1.00 46.66  ? 149 THR B CA  1 
ATOM   3910 C C   . THR B 1 152 ? 123.991 58.573  201.454 1.00 50.42  ? 149 THR B C   1 
ATOM   3911 O O   . THR B 1 152 ? 124.234 59.239  202.474 1.00 48.34  ? 149 THR B O   1 
ATOM   3912 C CB  . THR B 1 152 ? 122.429 59.375  199.629 1.00 45.03  ? 149 THR B CB  1 
ATOM   3913 O OG1 . THR B 1 152 ? 122.384 60.011  198.352 1.00 44.84  ? 149 THR B OG1 1 
ATOM   3914 C CG2 . THR B 1 152 ? 121.625 60.214  200.604 1.00 56.91  ? 149 THR B CG2 1 
ATOM   3915 N N   . MET B 1 153 ? 123.875 57.239  201.486 1.00 50.68  ? 150 MET B N   1 
ATOM   3916 C CA  . MET B 1 153 ? 123.911 56.513  202.749 1.00 47.58  ? 150 MET B CA  1 
ATOM   3917 C C   . MET B 1 153 ? 125.303 56.446  203.347 1.00 47.75  ? 150 MET B C   1 
ATOM   3918 O O   . MET B 1 153 ? 125.422 56.320  204.563 1.00 56.46  ? 150 MET B O   1 
ATOM   3919 C CB  . MET B 1 153 ? 123.386 55.091  202.567 1.00 48.45  ? 150 MET B CB  1 
ATOM   3920 C CG  . MET B 1 153 ? 121.971 55.023  202.032 1.00 56.17  ? 150 MET B CG  1 
ATOM   3921 S SD  . MET B 1 153 ? 120.797 55.726  203.199 1.00 53.67  ? 150 MET B SD  1 
ATOM   3922 C CE  . MET B 1 153 ? 120.751 54.376  204.379 1.00 47.49  ? 150 MET B CE  1 
ATOM   3923 N N   . THR B 1 154 ? 126.359 56.573  202.555 1.00 46.25  ? 151 THR B N   1 
ATOM   3924 C CA  . THR B 1 154 ? 127.676 56.555  203.162 1.00 44.38  ? 151 THR B CA  1 
ATOM   3925 C C   . THR B 1 154 ? 128.299 57.929  203.266 1.00 44.80  ? 151 THR B C   1 
ATOM   3926 O O   . THR B 1 154 ? 129.209 58.110  204.071 1.00 50.43  ? 151 THR B O   1 
ATOM   3927 C CB  . THR B 1 154 ? 128.647 55.644  202.407 1.00 46.30  ? 151 THR B CB  1 
ATOM   3928 O OG1 . THR B 1 154 ? 129.129 56.296  201.226 1.00 47.12  ? 151 THR B OG1 1 
ATOM   3929 C CG2 . THR B 1 154 ? 127.972 54.341  202.068 1.00 47.03  ? 151 THR B CG2 1 
ATOM   3930 N N   . LYS B 1 155 ? 127.862 58.896  202.482 1.00 44.43  ? 152 LYS B N   1 
ATOM   3931 C CA  . LYS B 1 155 ? 128.500 60.197  202.536 1.00 42.80  ? 152 LYS B CA  1 
ATOM   3932 C C   . LYS B 1 155 ? 127.616 61.286  203.127 1.00 45.10  ? 152 LYS B C   1 
ATOM   3933 O O   . LYS B 1 155 ? 128.066 62.430  203.217 1.00 43.84  ? 152 LYS B O   1 
ATOM   3934 C CB  . LYS B 1 155 ? 128.982 60.600  201.143 1.00 41.87  ? 152 LYS B CB  1 
ATOM   3935 C CG  . LYS B 1 155 ? 129.724 59.484  200.429 1.00 44.98  ? 152 LYS B CG  1 
ATOM   3936 C CD  . LYS B 1 155 ? 130.451 59.951  199.172 1.00 42.86  ? 152 LYS B CD  1 
ATOM   3937 C CE  . LYS B 1 155 ? 131.271 58.808  198.609 1.00 46.75  ? 152 LYS B CE  1 
ATOM   3938 N NZ  . LYS B 1 155 ? 131.650 57.842  199.706 1.00 50.69  ? 152 LYS B NZ  1 
ATOM   3939 N N   . PHE B 1 156 ? 126.366 60.989  203.503 1.00 46.82  ? 153 PHE B N   1 
ATOM   3940 C CA  . PHE B 1 156 ? 125.524 62.048  204.060 1.00 46.15  ? 153 PHE B CA  1 
ATOM   3941 C C   . PHE B 1 156 ? 124.625 61.566  205.196 1.00 51.22  ? 153 PHE B C   1 
ATOM   3942 O O   . PHE B 1 156 ? 124.616 62.133  206.297 1.00 47.39  ? 153 PHE B O   1 
ATOM   3943 C CB  . PHE B 1 156 ? 124.667 62.682  202.971 1.00 40.91  ? 153 PHE B CB  1 
ATOM   3944 C CG  . PHE B 1 156 ? 123.607 63.585  203.495 1.00 42.02  ? 153 PHE B CG  1 
ATOM   3945 C CD1 . PHE B 1 156 ? 123.934 64.715  204.202 1.00 42.53  ? 153 PHE B CD1 1 
ATOM   3946 C CD2 . PHE B 1 156 ? 122.275 63.307  203.285 1.00 51.05  ? 153 PHE B CD2 1 
ATOM   3947 C CE1 . PHE B 1 156 ? 122.951 65.562  204.701 1.00 45.75  ? 153 PHE B CE1 1 
ATOM   3948 C CE2 . PHE B 1 156 ? 121.280 64.162  203.787 1.00 51.84  ? 153 PHE B CE2 1 
ATOM   3949 C CZ  . PHE B 1 156 ? 121.628 65.290  204.491 1.00 45.32  ? 153 PHE B CZ  1 
ATOM   3950 N N   . MET B 1 157 ? 123.816 60.558  204.920 1.00 53.33  ? 154 MET B N   1 
ATOM   3951 C CA  . MET B 1 157 ? 122.886 60.077  205.923 1.00 50.17  ? 154 MET B CA  1 
ATOM   3952 C C   . MET B 1 157 ? 123.573 59.127  206.883 1.00 55.65  ? 154 MET B C   1 
ATOM   3953 O O   . MET B 1 157 ? 124.320 58.231  206.475 1.00 58.42  ? 154 MET B O   1 
ATOM   3954 C CB  . MET B 1 157 ? 121.693 59.394  205.268 1.00 51.83  ? 154 MET B CB  1 
ATOM   3955 C CG  . MET B 1 157 ? 120.550 60.340  205.067 1.00 54.20  ? 154 MET B CG  1 
ATOM   3956 S SD  . MET B 1 157 ? 119.160 59.566  204.272 1.00 67.87  ? 154 MET B SD  1 
ATOM   3957 C CE  . MET B 1 157 ? 118.088 60.988  204.065 1.00 51.85  ? 154 MET B CE  1 
ATOM   3958 N N   . GLN B 1 158 ? 123.344 59.351  208.158 1.00 56.91  ? 155 GLN B N   1 
ATOM   3959 C CA  . GLN B 1 158 ? 123.765 58.443  209.205 1.00 52.76  ? 155 GLN B CA  1 
ATOM   3960 C C   . GLN B 1 158 ? 122.490 57.908  209.828 1.00 49.65  ? 155 GLN B C   1 
ATOM   3961 O O   . GLN B 1 158 ? 121.803 58.617  210.562 1.00 52.16  ? 155 GLN B O   1 
ATOM   3962 C CB  . GLN B 1 158 ? 124.626 59.175  210.204 1.00 54.62  ? 155 GLN B CB  1 
ATOM   3963 C CG  . GLN B 1 158 ? 125.497 60.176  209.541 1.00 55.16  ? 155 GLN B CG  1 
ATOM   3964 C CD  . GLN B 1 158 ? 126.116 61.117  210.524 1.00 69.27  ? 155 GLN B CD  1 
ATOM   3965 O OE1 . GLN B 1 158 ? 125.525 62.151  210.874 1.00 67.37  ? 155 GLN B OE1 1 
ATOM   3966 N NE2 . GLN B 1 158 ? 127.306 60.760  211.011 1.00 76.09  ? 155 GLN B NE2 1 
ATOM   3967 N N   . VAL B 1 159 ? 122.142 56.681  209.487 1.00 47.69  ? 156 VAL B N   1 
ATOM   3968 C CA  . VAL B 1 159 ? 120.943 56.054  210.016 1.00 50.04  ? 156 VAL B CA  1 
ATOM   3969 C C   . VAL B 1 159 ? 121.358 55.244  211.226 1.00 54.63  ? 156 VAL B C   1 
ATOM   3970 O O   . VAL B 1 159 ? 122.131 54.285  211.128 1.00 54.37  ? 156 VAL B O   1 
ATOM   3971 C CB  . VAL B 1 159 ? 120.247 55.177  208.972 1.00 50.51  ? 156 VAL B CB  1 
ATOM   3972 C CG1 . VAL B 1 159 ? 118.936 54.678  209.496 1.00 46.69  ? 156 VAL B CG1 1 
ATOM   3973 C CG2 . VAL B 1 159 ? 120.031 55.965  207.689 1.00 58.39  ? 156 VAL B CG2 1 
ATOM   3974 N N   . ARG B 1 160 ? 120.878 55.652  212.365 1.00 53.81  ? 157 ARG B N   1 
ATOM   3975 C CA  . ARG B 1 160 ? 121.017 55.024  213.658 1.00 47.52  ? 157 ARG B CA  1 
ATOM   3976 C C   . ARG B 1 160 ? 119.906 54.004  213.857 1.00 48.59  ? 157 ARG B C   1 
ATOM   3977 O O   . ARG B 1 160 ? 118.804 54.193  213.334 1.00 48.99  ? 157 ARG B O   1 
ATOM   3978 C CB  . ARG B 1 160 ? 120.971 56.074  214.748 1.00 52.84  ? 157 ARG B CB  1 
ATOM   3979 C CG  . ARG B 1 160 ? 122.152 56.990  214.677 1.00 51.54  ? 157 ARG B CG  1 
ATOM   3980 C CD  . ARG B 1 160 ? 121.809 58.389  215.129 1.00 61.25  ? 157 ARG B CD  1 
ATOM   3981 N NE  . ARG B 1 160 ? 122.974 59.235  214.924 1.00 70.34  ? 157 ARG B NE  1 
ATOM   3982 C CZ  . ARG B 1 160 ? 123.165 60.004  213.861 1.00 74.52  ? 157 ARG B CZ  1 
ATOM   3983 N NH1 . ARG B 1 160 ? 122.234 60.130  212.918 1.00 72.46  ? 157 ARG B NH1 1 
ATOM   3984 N NH2 . ARG B 1 160 ? 124.325 60.646  213.725 1.00 68.50  ? 157 ARG B NH2 1 
ATOM   3985 N N   . PRO B 1 161 ? 120.170 52.885  214.541 1.00 51.08  ? 158 PRO B N   1 
ATOM   3986 C CA  . PRO B 1 161 ? 119.084 51.933  214.826 1.00 49.70  ? 158 PRO B CA  1 
ATOM   3987 C C   . PRO B 1 161 ? 117.938 52.616  215.558 1.00 47.79  ? 158 PRO B C   1 
ATOM   3988 O O   . PRO B 1 161 ? 118.148 53.353  216.519 1.00 48.10  ? 158 PRO B O   1 
ATOM   3989 C CB  . PRO B 1 161 ? 119.757 50.863  215.696 1.00 45.84  ? 158 PRO B CB  1 
ATOM   3990 C CG  . PRO B 1 161 ? 121.229 51.007  215.448 1.00 48.02  ? 158 PRO B CG  1 
ATOM   3991 C CD  . PRO B 1 161 ? 121.452 52.465  215.144 1.00 49.72  ? 158 PRO B CD  1 
ATOM   3992 N N   . GLY B 1 162 ? 116.720 52.425  215.049 1.00 52.96  ? 159 GLY B N   1 
ATOM   3993 C CA  . GLY B 1 162 ? 115.525 53.032  215.600 1.00 50.77  ? 159 GLY B CA  1 
ATOM   3994 C C   . GLY B 1 162 ? 114.927 54.128  214.748 1.00 47.28  ? 159 GLY B C   1 
ATOM   3995 O O   . GLY B 1 162 ? 113.699 54.255  214.704 1.00 52.70  ? 159 GLY B O   1 
ATOM   3996 N N   . ASP B 1 163 ? 115.758 54.870  214.017 1.00 48.17  ? 160 ASP B N   1 
ATOM   3997 C CA  . ASP B 1 163 ? 115.275 55.935  213.146 1.00 48.62  ? 160 ASP B CA  1 
ATOM   3998 C C   . ASP B 1 163 ? 114.162 55.436  212.224 1.00 53.92  ? 160 ASP B C   1 
ATOM   3999 O O   . ASP B 1 163 ? 114.133 54.268  211.822 1.00 53.98  ? 160 ASP B O   1 
ATOM   4000 C CB  . ASP B 1 163 ? 116.437 56.463  212.302 1.00 48.42  ? 160 ASP B CB  1 
ATOM   4001 C CG  . ASP B 1 163 ? 117.489 57.172  213.117 1.00 50.43  ? 160 ASP B CG  1 
ATOM   4002 O OD1 . ASP B 1 163 ? 117.208 57.566  214.258 1.00 54.64  ? 160 ASP B OD1 1 
ATOM   4003 O OD2 . ASP B 1 163 ? 118.637 57.276  212.647 1.00 52.44  ? 160 ASP B OD2 1 
ATOM   4004 N N   . THR B 1 164 ? 113.234 56.330  211.875 1.00 53.28  ? 161 THR B N   1 
ATOM   4005 C CA  . THR B 1 164 ? 112.255 56.032  210.833 1.00 57.66  ? 161 THR B CA  1 
ATOM   4006 C C   . THR B 1 164 ? 112.658 56.752  209.557 1.00 57.83  ? 161 THR B C   1 
ATOM   4007 O O   . THR B 1 164 ? 112.737 57.986  209.525 1.00 59.87  ? 161 THR B O   1 
ATOM   4008 C CB  . THR B 1 164 ? 110.823 56.424  211.199 1.00 59.64  ? 161 THR B CB  1 
ATOM   4009 O OG1 . THR B 1 164 ? 110.254 55.442  212.076 1.00 66.26  ? 161 THR B OG1 1 
ATOM   4010 C CG2 . THR B 1 164 ? 109.981 56.492  209.925 1.00 52.89  ? 161 THR B CG2 1 
ATOM   4011 N N   . VAL B 1 165 ? 112.893 55.979  208.506 1.00 55.03  ? 162 VAL B N   1 
ATOM   4012 C CA  . VAL B 1 165 ? 113.377 56.495  207.241 1.00 51.61  ? 162 VAL B CA  1 
ATOM   4013 C C   . VAL B 1 165 ? 112.213 56.432  206.255 1.00 48.26  ? 162 VAL B C   1 
ATOM   4014 O O   . VAL B 1 165 ? 111.588 55.378  206.080 1.00 46.69  ? 162 VAL B O   1 
ATOM   4015 C CB  . VAL B 1 165 ? 114.601 55.690  206.772 1.00 50.63  ? 162 VAL B CB  1 
ATOM   4016 C CG1 . VAL B 1 165 ? 115.085 56.167  205.433 1.00 48.80  ? 162 VAL B CG1 1 
ATOM   4017 C CG2 . VAL B 1 165 ? 115.695 55.781  207.808 1.00 47.78  ? 162 VAL B CG2 1 
ATOM   4018 N N   . VAL B 1 166 ? 111.898 57.562  205.640 1.00 44.80  ? 163 VAL B N   1 
ATOM   4019 C CA  . VAL B 1 166 ? 110.835 57.635  204.651 1.00 49.50  ? 163 VAL B CA  1 
ATOM   4020 C C   . VAL B 1 166 ? 111.497 57.808  203.296 1.00 50.42  ? 163 VAL B C   1 
ATOM   4021 O O   . VAL B 1 166 ? 112.308 58.722  203.112 1.00 51.56  ? 163 VAL B O   1 
ATOM   4022 C CB  . VAL B 1 166 ? 109.866 58.792  204.943 1.00 49.37  ? 163 VAL B CB  1 
ATOM   4023 C CG1 . VAL B 1 166 ? 108.798 58.864  203.883 1.00 48.95  ? 163 VAL B CG1 1 
ATOM   4024 C CG2 . VAL B 1 166 ? 109.232 58.630  206.295 1.00 50.52  ? 163 VAL B CG2 1 
ATOM   4025 N N   . VAL B 1 167 ? 111.170 56.924  202.358 1.00 47.32  ? 164 VAL B N   1 
ATOM   4026 C CA  . VAL B 1 167 ? 111.740 56.935  201.018 1.00 52.36  ? 164 VAL B CA  1 
ATOM   4027 C C   . VAL B 1 167 ? 110.593 57.109  200.041 1.00 59.04  ? 164 VAL B C   1 
ATOM   4028 O O   . VAL B 1 167 ? 109.696 56.264  199.988 1.00 62.86  ? 164 VAL B O   1 
ATOM   4029 C CB  . VAL B 1 167 ? 112.505 55.638  200.730 1.00 53.18  ? 164 VAL B CB  1 
ATOM   4030 C CG1 . VAL B 1 167 ? 113.062 55.660  199.340 1.00 55.39  ? 164 VAL B CG1 1 
ATOM   4031 C CG2 . VAL B 1 167 ? 113.607 55.430  201.750 1.00 54.26  ? 164 VAL B CG2 1 
ATOM   4032 N N   . SER B 1 168 ? 110.621 58.184  199.259 1.00 56.79  ? 165 SER B N   1 
ATOM   4033 C CA  . SER B 1 168 ? 109.547 58.445  198.311 1.00 58.01  ? 165 SER B CA  1 
ATOM   4034 C C   . SER B 1 168 ? 109.959 58.019  196.911 1.00 58.87  ? 165 SER B C   1 
ATOM   4035 O O   . SER B 1 168 ? 111.133 58.086  196.547 1.00 60.67  ? 165 SER B O   1 
ATOM   4036 C CB  . SER B 1 168 ? 109.119 59.913  198.338 1.00 56.40  ? 165 SER B CB  1 
ATOM   4037 O OG  . SER B 1 168 ? 110.201 60.774  198.102 1.00 56.72  ? 165 SER B OG  1 
ATOM   4038 N N   . GLY B 1 169 ? 108.974 57.593  196.125 1.00 60.72  ? 166 GLY B N   1 
ATOM   4039 C CA  . GLY B 1 169 ? 109.282 56.896  194.889 1.00 72.79  ? 166 GLY B CA  1 
ATOM   4040 C C   . GLY B 1 169 ? 110.078 55.649  195.189 1.00 70.59  ? 166 GLY B C   1 
ATOM   4041 O O   . GLY B 1 169 ? 111.054 55.330  194.496 1.00 68.10  ? 166 GLY B O   1 
ATOM   4042 N N   . ALA B 1 170 ? 109.681 54.942  196.231 1.00 65.77  ? 167 ALA B N   1 
ATOM   4043 C CA  . ALA B 1 170 ? 110.500 53.846  196.703 1.00 66.51  ? 167 ALA B CA  1 
ATOM   4044 C C   . ALA B 1 170 ? 110.560 52.716  195.692 1.00 70.48  ? 167 ALA B C   1 
ATOM   4045 O O   . ALA B 1 170 ? 111.564 52.005  195.629 1.00 70.25  ? 167 ALA B O   1 
ATOM   4046 C CB  . ALA B 1 170 ? 109.969 53.343  198.039 1.00 63.76  ? 167 ALA B CB  1 
ATOM   4047 N N   . SER B 1 171 ? 109.499 52.517  194.914 1.00 71.27  ? 168 SER B N   1 
ATOM   4048 C CA  . SER B 1 171 ? 109.412 51.342  194.052 1.00 78.57  ? 168 SER B CA  1 
ATOM   4049 C C   . SER B 1 171 ? 110.545 51.257  193.019 1.00 84.89  ? 168 SER B C   1 
ATOM   4050 O O   . SER B 1 171 ? 110.842 50.161  192.515 1.00 85.60  ? 168 SER B O   1 
ATOM   4051 C CB  . SER B 1 171 ? 108.045 51.342  193.384 1.00 86.27  ? 168 SER B CB  1 
ATOM   4052 O OG  . SER B 1 171 ? 107.773 52.628  192.865 1.00 97.41  ? 168 SER B OG  1 
ATOM   4053 N N   . GLY B 1 172 ? 111.172 52.379  192.673 1.00 81.09  ? 169 GLY B N   1 
ATOM   4054 C CA  . GLY B 1 172 ? 112.272 52.358  191.734 1.00 80.39  ? 169 GLY B CA  1 
ATOM   4055 C C   . GLY B 1 172 ? 113.571 51.908  192.364 1.00 73.72  ? 169 GLY B C   1 
ATOM   4056 O O   . GLY B 1 172 ? 113.646 51.560  193.541 1.00 67.94  ? 169 GLY B O   1 
ATOM   4057 N N   . MET B 1 173 ? 114.625 51.924  191.549 1.00 73.96  ? 170 MET B N   1 
ATOM   4058 C CA  . MET B 1 173 ? 115.852 51.280  191.985 1.00 62.58  ? 170 MET B CA  1 
ATOM   4059 C C   . MET B 1 173 ? 116.608 52.091  193.019 1.00 60.36  ? 170 MET B C   1 
ATOM   4060 O O   . MET B 1 173 ? 117.136 51.516  193.970 1.00 68.14  ? 170 MET B O   1 
ATOM   4061 C CB  . MET B 1 173 ? 116.762 50.977  190.814 1.00 65.33  ? 170 MET B CB  1 
ATOM   4062 C CG  . MET B 1 173 ? 117.481 49.674  191.050 1.00 67.54  ? 170 MET B CG  1 
ATOM   4063 S SD  . MET B 1 173 ? 119.062 49.746  190.274 1.00 57.69  ? 170 MET B SD  1 
ATOM   4064 C CE  . MET B 1 173 ? 119.669 51.029  191.312 1.00 54.19  ? 170 MET B CE  1 
ATOM   4065 N N   . ILE B 1 174 ? 116.704 53.409  192.869 1.00 58.54  ? 171 ILE B N   1 
ATOM   4066 C CA  . ILE B 1 174 ? 117.378 54.176  193.909 1.00 55.00  ? 171 ILE B CA  1 
ATOM   4067 C C   . ILE B 1 174 ? 116.602 54.084  195.215 1.00 58.12  ? 171 ILE B C   1 
ATOM   4068 O O   . ILE B 1 174 ? 117.180 53.871  196.286 1.00 55.92  ? 171 ILE B O   1 
ATOM   4069 C CB  . ILE B 1 174 ? 117.578 55.631  193.475 1.00 54.64  ? 171 ILE B CB  1 
ATOM   4070 C CG1 . ILE B 1 174 ? 118.481 55.701  192.261 1.00 56.42  ? 171 ILE B CG1 1 
ATOM   4071 C CG2 . ILE B 1 174 ? 118.170 56.423  194.595 1.00 52.93  ? 171 ILE B CG2 1 
ATOM   4072 C CD1 . ILE B 1 174 ? 118.864 57.105  191.918 1.00 58.62  ? 171 ILE B CD1 1 
ATOM   4073 N N   . GLY B 1 175 ? 115.274 54.176  195.139 1.00 64.24  ? 172 GLY B N   1 
ATOM   4074 C CA  . GLY B 1 175 ? 114.473 54.142  196.349 1.00 57.11  ? 172 GLY B CA  1 
ATOM   4075 C C   . GLY B 1 175 ? 114.516 52.801  197.058 1.00 59.86  ? 172 GLY B C   1 
ATOM   4076 O O   . GLY B 1 175 ? 114.630 52.748  198.286 1.00 60.34  ? 172 GLY B O   1 
ATOM   4077 N N   . THR B 1 176 ? 114.426 51.695  196.307 1.00 62.58  ? 173 THR B N   1 
ATOM   4078 C CA  . THR B 1 176 ? 114.553 50.388  196.951 1.00 61.17  ? 173 THR B CA  1 
ATOM   4079 C C   . THR B 1 176 ? 115.952 50.193  197.513 1.00 60.46  ? 173 THR B C   1 
ATOM   4080 O O   . THR B 1 176 ? 116.108 49.628  198.602 1.00 60.26  ? 173 THR B O   1 
ATOM   4081 C CB  . THR B 1 176 ? 114.209 49.243  195.999 1.00 56.93  ? 173 THR B CB  1 
ATOM   4082 O OG1 . THR B 1 176 ? 114.863 49.458  194.752 1.00 69.03  ? 173 THR B OG1 1 
ATOM   4083 C CG2 . THR B 1 176 ? 112.721 49.126  195.787 1.00 59.88  ? 173 THR B CG2 1 
ATOM   4084 N N   . LEU B 1 177 ? 116.981 50.644  196.788 1.00 57.03  ? 174 LEU B N   1 
ATOM   4085 C CA  . LEU B 1 177 ? 118.339 50.559  197.317 1.00 53.76  ? 174 LEU B CA  1 
ATOM   4086 C C   . LEU B 1 177 ? 118.454 51.290  198.645 1.00 55.10  ? 174 LEU B C   1 
ATOM   4087 O O   . LEU B 1 177 ? 118.909 50.720  199.646 1.00 50.83  ? 174 LEU B O   1 
ATOM   4088 C CB  . LEU B 1 177 ? 119.328 51.143  196.316 1.00 50.82  ? 174 LEU B CB  1 
ATOM   4089 C CG  . LEU B 1 177 ? 119.755 50.189  195.214 1.00 57.59  ? 174 LEU B CG  1 
ATOM   4090 C CD1 . LEU B 1 177 ? 120.934 50.753  194.451 1.00 50.53  ? 174 LEU B CD1 1 
ATOM   4091 C CD2 . LEU B 1 177 ? 120.083 48.854  195.849 1.00 60.12  ? 174 LEU B CD2 1 
ATOM   4092 N N   . VAL B 1 178 ? 117.989 52.542  198.680 1.00 55.52  ? 175 VAL B N   1 
ATOM   4093 C CA  . VAL B 1 178 ? 118.113 53.375  199.874 1.00 54.30  ? 175 VAL B CA  1 
ATOM   4094 C C   . VAL B 1 178 ? 117.392 52.739  201.058 1.00 54.05  ? 175 VAL B C   1 
ATOM   4095 O O   . VAL B 1 178 ? 117.935 52.669  202.165 1.00 50.10  ? 175 VAL B O   1 
ATOM   4096 C CB  . VAL B 1 178 ? 117.610 54.799  199.578 1.00 48.34  ? 175 VAL B CB  1 
ATOM   4097 C CG1 . VAL B 1 178 ? 117.123 55.474  200.855 1.00 52.74  ? 175 VAL B CG1 1 
ATOM   4098 C CG2 . VAL B 1 178 ? 118.733 55.597  198.975 1.00 42.13  ? 175 VAL B CG2 1 
ATOM   4099 N N   . GLY B 1 179 ? 116.155 52.282  200.847 1.00 54.43  ? 176 GLY B N   1 
ATOM   4100 C CA  . GLY B 1 179 ? 115.385 51.718  201.946 1.00 52.25  ? 176 GLY B CA  1 
ATOM   4101 C C   . GLY B 1 179 ? 116.030 50.487  202.559 1.00 53.92  ? 176 GLY B C   1 
ATOM   4102 O O   . GLY B 1 179 ? 116.038 50.325  203.781 1.00 54.82  ? 176 GLY B O   1 
ATOM   4103 N N   . GLN B 1 180 ? 116.572 49.598  201.717 1.00 53.39  ? 177 GLN B N   1 
ATOM   4104 C CA  . GLN B 1 180 ? 117.179 48.365  202.209 1.00 47.64  ? 177 GLN B CA  1 
ATOM   4105 C C   . GLN B 1 180 ? 118.433 48.646  203.018 1.00 52.31  ? 177 GLN B C   1 
ATOM   4106 O O   . GLN B 1 180 ? 118.726 47.934  203.982 1.00 57.94  ? 177 GLN B O   1 
ATOM   4107 C CB  . GLN B 1 180 ? 117.501 47.443  201.050 1.00 47.38  ? 177 GLN B CB  1 
ATOM   4108 C CG  . GLN B 1 180 ? 116.289 46.967  200.288 1.00 49.58  ? 177 GLN B CG  1 
ATOM   4109 C CD  . GLN B 1 180 ? 116.650 46.051  199.141 1.00 54.00  ? 177 GLN B CD  1 
ATOM   4110 O OE1 . GLN B 1 180 ? 117.029 44.903  199.344 1.00 56.72  ? 177 GLN B OE1 1 
ATOM   4111 N NE2 . GLN B 1 180 ? 116.596 46.578  197.931 1.00 57.03  ? 177 GLN B NE2 1 
ATOM   4112 N N   . MET B 1 181 ? 119.214 49.644  202.615 1.00 51.74  ? 178 MET B N   1 
ATOM   4113 C CA  . MET B 1 181 ? 120.353 50.046  203.428 1.00 51.85  ? 178 MET B CA  1 
ATOM   4114 C C   . MET B 1 181 ? 119.910 50.698  204.737 1.00 54.14  ? 178 MET B C   1 
ATOM   4115 O O   . MET B 1 181 ? 120.610 50.585  205.748 1.00 61.13  ? 178 MET B O   1 
ATOM   4116 C CB  . MET B 1 181 ? 121.251 51.001  202.644 1.00 55.71  ? 178 MET B CB  1 
ATOM   4117 C CG  . MET B 1 181 ? 121.699 50.454  201.296 1.00 61.38  ? 178 MET B CG  1 
ATOM   4118 S SD  . MET B 1 181 ? 122.708 51.617  200.327 1.00 58.43  ? 178 MET B SD  1 
ATOM   4119 C CE  . MET B 1 181 ? 124.289 51.456  201.158 1.00 57.70  ? 178 MET B CE  1 
ATOM   4120 N N   . ALA B 1 182 ? 118.788 51.416  204.746 1.00 50.39  ? 179 ALA B N   1 
ATOM   4121 C CA  . ALA B 1 182 ? 118.299 51.928  206.019 1.00 49.33  ? 179 ALA B CA  1 
ATOM   4122 C C   . ALA B 1 182 ? 117.741 50.793  206.867 1.00 55.88  ? 179 ALA B C   1 
ATOM   4123 O O   . ALA B 1 182 ? 118.035 50.703  208.067 1.00 55.14  ? 179 ALA B O   1 
ATOM   4124 C CB  . ALA B 1 182 ? 117.255 53.016  205.800 1.00 46.73  ? 179 ALA B CB  1 
ATOM   4125 N N   . LYS B 1 183 ? 116.988 49.876  206.243 1.00 55.14  ? 180 LYS B N   1 
ATOM   4126 C CA  . LYS B 1 183 ? 116.528 48.690  206.960 1.00 55.16  ? 180 LYS B CA  1 
ATOM   4127 C C   . LYS B 1 183 ? 117.710 47.946  207.573 1.00 59.59  ? 180 LYS B C   1 
ATOM   4128 O O   . LYS B 1 183 ? 117.655 47.535  208.740 1.00 61.51  ? 180 LYS B O   1 
ATOM   4129 C CB  . LYS B 1 183 ? 115.725 47.782  206.022 1.00 49.90  ? 180 LYS B CB  1 
ATOM   4130 C CG  . LYS B 1 183 ? 115.082 46.553  206.678 1.00 55.05  ? 180 LYS B CG  1 
ATOM   4131 C CD  . LYS B 1 183 ? 114.048 46.927  207.750 1.00 69.54  ? 180 LYS B CD  1 
ATOM   4132 C CE  . LYS B 1 183 ? 113.879 45.816  208.830 1.00 75.21  ? 180 LYS B CE  1 
ATOM   4133 N NZ  . LYS B 1 183 ? 113.156 46.221  210.113 1.00 60.76  ? 180 LYS B NZ  1 
ATOM   4134 N N   . ARG B 1 184 ? 118.822 47.846  206.832 1.00 59.54  ? 181 ARG B N   1 
ATOM   4135 C CA  . ARG B 1 184 ? 120.012 47.166  207.345 1.00 59.92  ? 181 ARG B CA  1 
ATOM   4136 C C   . ARG B 1 184 ? 120.709 47.963  208.437 1.00 58.39  ? 181 ARG B C   1 
ATOM   4137 O O   . ARG B 1 184 ? 121.398 47.376  209.283 1.00 57.93  ? 181 ARG B O   1 
ATOM   4138 C CB  . ARG B 1 184 ? 120.991 46.872  206.219 1.00 52.29  ? 181 ARG B CB  1 
ATOM   4139 C CG  . ARG B 1 184 ? 120.652 45.625  205.447 1.00 59.07  ? 181 ARG B CG  1 
ATOM   4140 C CD  . ARG B 1 184 ? 121.496 45.566  204.211 1.00 63.16  ? 181 ARG B CD  1 
ATOM   4141 N NE  . ARG B 1 184 ? 122.842 46.060  204.472 1.00 64.16  ? 181 ARG B NE  1 
ATOM   4142 C CZ  . ARG B 1 184 ? 123.843 45.313  204.909 1.00 63.97  ? 181 ARG B CZ  1 
ATOM   4143 N NH1 . ARG B 1 184 ? 123.668 44.030  205.200 1.00 60.83  ? 181 ARG B NH1 1 
ATOM   4144 N NH2 . ARG B 1 184 ? 125.046 45.868  205.060 1.00 59.52  ? 181 ARG B NH2 1 
ATOM   4145 N N   . ALA B 1 185 ? 120.557 49.281  208.432 1.00 53.53  ? 182 ALA B N   1 
ATOM   4146 C CA  . ALA B 1 185 ? 121.168 50.114  209.457 1.00 58.81  ? 182 ALA B CA  1 
ATOM   4147 C C   . ALA B 1 185 ? 120.321 50.204  210.715 1.00 55.96  ? 182 ALA B C   1 
ATOM   4148 O O   . ALA B 1 185 ? 120.697 50.907  211.667 1.00 47.49  ? 182 ALA B O   1 
ATOM   4149 C CB  . ALA B 1 185 ? 121.424 51.515  208.893 1.00 58.38  ? 182 ALA B CB  1 
ATOM   4150 N N   . GLY B 1 186 ? 119.221 49.467  210.753 1.00 55.47  ? 183 GLY B N   1 
ATOM   4151 C CA  . GLY B 1 186 ? 118.367 49.429  211.906 1.00 53.56  ? 183 GLY B CA  1 
ATOM   4152 C C   . GLY B 1 186 ? 117.199 50.380  211.860 1.00 55.37  ? 183 GLY B C   1 
ATOM   4153 O O   . GLY B 1 186 ? 116.770 50.848  212.915 1.00 56.99  ? 183 GLY B O   1 
ATOM   4154 N N   . ALA B 1 187 ? 116.681 50.703  210.682 1.00 56.33  ? 184 ALA B N   1 
ATOM   4155 C CA  . ALA B 1 187 ? 115.621 51.692  210.575 1.00 52.45  ? 184 ALA B CA  1 
ATOM   4156 C C   . ALA B 1 187 ? 114.278 51.036  210.301 1.00 55.14  ? 184 ALA B C   1 
ATOM   4157 O O   . ALA B 1 187 ? 114.192 49.994  209.645 1.00 55.87  ? 184 ALA B O   1 
ATOM   4158 C CB  . ALA B 1 187 ? 115.903 52.704  209.470 1.00 52.07  ? 184 ALA B CB  1 
ATOM   4159 N N   . ARG B 1 188 ? 113.232 51.639  210.848 1.00 53.74  ? 185 ARG B N   1 
ATOM   4160 C CA  . ARG B 1 188 ? 111.889 51.403  210.348 1.00 55.11  ? 185 ARG B CA  1 
ATOM   4161 C C   . ARG B 1 188 ? 111.762 52.176  209.033 1.00 56.38  ? 185 ARG B C   1 
ATOM   4162 O O   . ARG B 1 188 ? 112.028 53.385  208.989 1.00 53.29  ? 185 ARG B O   1 
ATOM   4163 C CB  . ARG B 1 188 ? 110.868 51.841  211.398 1.00 52.29  ? 185 ARG B CB  1 
ATOM   4164 C CG  . ARG B 1 188 ? 109.453 51.927  210.904 1.00 58.13  ? 185 ARG B CG  1 
ATOM   4165 C CD  . ARG B 1 188 ? 108.472 52.270  212.004 1.00 52.70  ? 185 ARG B CD  1 
ATOM   4166 N NE  . ARG B 1 188 ? 107.105 52.018  211.564 1.00 59.07  ? 185 ARG B NE  1 
ATOM   4167 C CZ  . ARG B 1 188 ? 106.601 50.809  211.341 1.00 64.52  ? 185 ARG B CZ  1 
ATOM   4168 N NH1 . ARG B 1 188 ? 107.331 49.710  211.504 1.00 62.26  ? 185 ARG B NH1 1 
ATOM   4169 N NH2 . ARG B 1 188 ? 105.338 50.696  210.933 1.00 63.27  ? 185 ARG B NH2 1 
ATOM   4170 N N   . VAL B 1 189 ? 111.392 51.493  207.953 1.00 55.26  ? 186 VAL B N   1 
ATOM   4171 C CA  . VAL B 1 189 ? 111.439 52.087  206.617 1.00 54.27  ? 186 VAL B CA  1 
ATOM   4172 C C   . VAL B 1 189 ? 110.026 52.238  206.057 1.00 55.14  ? 186 VAL B C   1 
ATOM   4173 O O   . VAL B 1 189 ? 109.245 51.279  206.029 1.00 54.24  ? 186 VAL B O   1 
ATOM   4174 C CB  . VAL B 1 189 ? 112.334 51.266  205.678 1.00 47.56  ? 186 VAL B CB  1 
ATOM   4175 C CG1 . VAL B 1 189 ? 112.319 51.861  204.312 1.00 50.75  ? 186 VAL B CG1 1 
ATOM   4176 C CG2 . VAL B 1 189 ? 113.747 51.248  206.208 1.00 50.35  ? 186 VAL B CG2 1 
ATOM   4177 N N   . VAL B 1 190 ? 109.706 53.446  205.605 1.00 50.33  ? 187 VAL B N   1 
ATOM   4178 C CA  . VAL B 1 190 ? 108.423 53.758  204.999 1.00 50.04  ? 187 VAL B CA  1 
ATOM   4179 C C   . VAL B 1 190 ? 108.653 54.227  203.567 1.00 59.04  ? 187 VAL B C   1 
ATOM   4180 O O   . VAL B 1 190 ? 109.463 55.130  203.326 1.00 61.24  ? 187 VAL B O   1 
ATOM   4181 C CB  . VAL B 1 190 ? 107.685 54.824  205.819 1.00 50.16  ? 187 VAL B CB  1 
ATOM   4182 C CG1 . VAL B 1 190 ? 106.342 55.123  205.213 1.00 54.13  ? 187 VAL B CG1 1 
ATOM   4183 C CG2 . VAL B 1 190 ? 107.520 54.331  207.237 1.00 56.71  ? 187 VAL B CG2 1 
ATOM   4184 N N   . GLY B 1 191 ? 107.924 53.629  202.621 1.00 57.30  ? 188 GLY B N   1 
ATOM   4185 C CA  . GLY B 1 191 ? 108.022 53.974  201.222 1.00 59.51  ? 188 GLY B CA  1 
ATOM   4186 C C   . GLY B 1 191 ? 106.668 54.371  200.661 1.00 63.70  ? 188 GLY B C   1 
ATOM   4187 O O   . GLY B 1 191 ? 105.649 54.321  201.352 1.00 65.40  ? 188 GLY B O   1 
ATOM   4188 N N   . THR B 1 192 ? 106.670 54.742  199.381 1.00 61.53  ? 189 THR B N   1 
ATOM   4189 C CA  . THR B 1 192 ? 105.462 55.227  198.727 1.00 67.80  ? 189 THR B CA  1 
ATOM   4190 C C   . THR B 1 192 ? 105.283 54.532  197.392 1.00 76.89  ? 189 THR B C   1 
ATOM   4191 O O   . THR B 1 192 ? 106.213 54.478  196.577 1.00 84.57  ? 189 THR B O   1 
ATOM   4192 C CB  . THR B 1 192 ? 105.510 56.732  198.493 1.00 68.58  ? 189 THR B CB  1 
ATOM   4193 O OG1 . THR B 1 192 ? 106.700 57.049  197.763 1.00 72.29  ? 189 THR B OG1 1 
ATOM   4194 C CG2 . THR B 1 192 ? 105.500 57.485  199.810 1.00 55.16  ? 189 THR B CG2 1 
ATOM   4195 N N   . ALA B 1 193 ? 104.078 54.039  197.155 1.00 77.04  ? 190 ALA B N   1 
ATOM   4196 C CA  . ALA B 1 193 ? 103.781 53.285  195.954 1.00 84.97  ? 190 ALA B CA  1 
ATOM   4197 C C   . ALA B 1 193 ? 102.470 53.787  195.365 1.00 90.52  ? 190 ALA B C   1 
ATOM   4198 O O   . ALA B 1 193 ? 101.731 54.544  196.002 1.00 91.98  ? 190 ALA B O   1 
ATOM   4199 C CB  . ALA B 1 193 ? 103.717 51.787  196.263 1.00 85.86  ? 190 ALA B CB  1 
ATOM   4200 N N   . GLY B 1 194 ? 102.200 53.387  194.118 1.00 92.92  ? 191 GLY B N   1 
ATOM   4201 C CA  . GLY B 1 194 ? 101.020 53.847  193.403 1.00 94.31  ? 191 GLY B CA  1 
ATOM   4202 C C   . GLY B 1 194 ? 99.939  52.796  193.218 1.00 92.45  ? 191 GLY B C   1 
ATOM   4203 O O   . GLY B 1 194 ? 98.792  53.130  192.909 1.00 92.84  ? 191 GLY B O   1 
ATOM   4204 N N   . SER B 1 195 ? 100.291 51.529  193.436 1.00 86.16  ? 192 SER B N   1 
ATOM   4205 C CA  . SER B 1 195 ? 99.372  50.412  193.292 1.00 84.59  ? 192 SER B CA  1 
ATOM   4206 C C   . SER B 1 195 ? 99.715  49.377  194.339 1.00 86.94  ? 192 SER B C   1 
ATOM   4207 O O   . SER B 1 195 ? 100.784 49.416  194.949 1.00 92.26  ? 192 SER B O   1 
ATOM   4208 C CB  . SER B 1 195 ? 99.480  49.727  191.944 1.00 87.70  ? 192 SER B CB  1 
ATOM   4209 O OG  . SER B 1 195 ? 100.655 48.931  191.934 1.00 86.04  ? 192 SER B OG  1 
ATOM   4210 N N   . ALA B 1 196 ? 98.806  48.422  194.527 1.00 82.91  ? 193 ALA B N   1 
ATOM   4211 C CA  . ALA B 1 196 ? 99.140  47.289  195.381 1.00 84.49  ? 193 ALA B CA  1 
ATOM   4212 C C   . ALA B 1 196 ? 100.308 46.509  194.793 1.00 88.49  ? 193 ALA B C   1 
ATOM   4213 O O   . ALA B 1 196 ? 101.126 45.947  195.533 1.00 86.40  ? 193 ALA B O   1 
ATOM   4214 C CB  . ALA B 1 196 ? 97.923  46.387  195.568 1.00 82.92  ? 193 ALA B CB  1 
ATOM   4215 N N   . GLY B 1 197 ? 100.395 46.472  193.461 1.00 87.31  ? 194 GLY B N   1 
ATOM   4216 C CA  . GLY B 1 197 ? 101.504 45.795  192.814 1.00 87.98  ? 194 GLY B CA  1 
ATOM   4217 C C   . GLY B 1 197 ? 102.838 46.384  193.217 1.00 89.11  ? 194 GLY B C   1 
ATOM   4218 O O   . GLY B 1 197 ? 103.762 45.657  193.588 1.00 91.83  ? 194 GLY B O   1 
ATOM   4219 N N   . LYS B 1 198 ? 102.965 47.713  193.134 1.00 89.09  ? 195 LYS B N   1 
ATOM   4220 C CA  . LYS B 1 198 ? 104.175 48.360  193.632 1.00 88.25  ? 195 LYS B CA  1 
ATOM   4221 C C   . LYS B 1 198 ? 104.294 48.239  195.149 1.00 84.77  ? 195 LYS B C   1 
ATOM   4222 O O   . LYS B 1 198 ? 105.387 47.998  195.675 1.00 83.10  ? 195 LYS B O   1 
ATOM   4223 C CB  . LYS B 1 198 ? 104.189 49.830  193.223 1.00 87.44  ? 195 LYS B CB  1 
ATOM   4224 C CG  . LYS B 1 198 ? 104.853 50.091  191.900 1.00 97.05  ? 195 LYS B CG  1 
ATOM   4225 C CD  . LYS B 1 198 ? 105.952 49.092  191.613 1.00 98.30  ? 195 LYS B CD  1 
ATOM   4226 C CE  . LYS B 1 198 ? 106.576 49.387  190.274 1.00 96.27  ? 195 LYS B CE  1 
ATOM   4227 N NZ  . LYS B 1 198 ? 107.457 50.587  190.304 1.00 94.37  ? 195 LYS B NZ  1 
ATOM   4228 N N   . ALA B 1 199 ? 103.177 48.378  195.865 1.00 80.51  ? 196 ALA B N   1 
ATOM   4229 C CA  . ALA B 1 199 ? 103.225 48.363  197.321 1.00 79.04  ? 196 ALA B CA  1 
ATOM   4230 C C   . ALA B 1 199 ? 103.620 46.991  197.860 1.00 81.62  ? 196 ALA B C   1 
ATOM   4231 O O   . ALA B 1 199 ? 104.396 46.894  198.820 1.00 74.78  ? 196 ALA B O   1 
ATOM   4232 C CB  . ALA B 1 199 ? 101.883 48.812  197.885 1.00 76.72  ? 196 ALA B CB  1 
ATOM   4233 N N   . ARG B 1 200 ? 103.072 45.918  197.281 1.00 83.68  ? 197 ARG B N   1 
ATOM   4234 C CA  . ARG B 1 200 ? 103.444 44.588  197.745 1.00 85.55  ? 197 ARG B CA  1 
ATOM   4235 C C   . ARG B 1 200 ? 104.862 44.253  197.325 1.00 85.37  ? 197 ARG B C   1 
ATOM   4236 O O   . ARG B 1 200 ? 105.554 43.493  198.019 1.00 80.55  ? 197 ARG B O   1 
ATOM   4237 C CB  . ARG B 1 200 ? 102.448 43.543  197.229 1.00 91.83  ? 197 ARG B CB  1 
ATOM   4238 C CG  . ARG B 1 200 ? 102.828 42.832  195.930 1.00 96.73  ? 197 ARG B CG  1 
ATOM   4239 C CD  . ARG B 1 200 ? 101.678 41.956  195.403 1.00 98.86  ? 197 ARG B CD  1 
ATOM   4240 N NE  . ARG B 1 200 ? 100.804 42.682  194.483 1.00 99.00  ? 197 ARG B NE  1 
ATOM   4241 C CZ  . ARG B 1 200 ? 99.638  43.219  194.816 1.00 94.29  ? 197 ARG B CZ  1 
ATOM   4242 N NH1 . ARG B 1 200 ? 99.164  43.130  196.050 1.00 93.40  ? 197 ARG B NH1 1 
ATOM   4243 N NH2 . ARG B 1 200 ? 98.928  43.859  193.886 1.00 83.80  ? 197 ARG B NH2 1 
ATOM   4244 N N   . TYR B 1 201 ? 105.301 44.811  196.191 1.00 80.90  ? 198 TYR B N   1 
ATOM   4245 C CA  . TYR B 1 201 ? 106.696 44.688  195.799 1.00 79.82  ? 198 TYR B CA  1 
ATOM   4246 C C   . TYR B 1 201 ? 107.568 45.325  196.856 1.00 81.08  ? 198 TYR B C   1 
ATOM   4247 O O   . TYR B 1 201 ? 108.603 44.770  197.235 1.00 79.29  ? 198 TYR B O   1 
ATOM   4248 C CB  . TYR B 1 201 ? 106.941 45.360  194.443 1.00 86.93  ? 198 TYR B CB  1 
ATOM   4249 C CG  . TYR B 1 201 ? 108.392 45.321  193.982 1.00 84.44  ? 198 TYR B CG  1 
ATOM   4250 C CD1 . TYR B 1 201 ? 109.041 44.105  193.842 1.00 82.52  ? 198 TYR B CD1 1 
ATOM   4251 C CD2 . TYR B 1 201 ? 109.111 46.484  193.708 1.00 80.23  ? 198 TYR B CD2 1 
ATOM   4252 C CE1 . TYR B 1 201 ? 110.346 44.031  193.437 1.00 81.47  ? 198 TYR B CE1 1 
ATOM   4253 C CE2 . TYR B 1 201 ? 110.436 46.419  193.298 1.00 78.42  ? 198 TYR B CE2 1 
ATOM   4254 C CZ  . TYR B 1 201 ? 111.044 45.179  193.162 1.00 82.30  ? 198 TYR B CZ  1 
ATOM   4255 O OH  . TYR B 1 201 ? 112.356 45.057  192.752 1.00 83.58  ? 198 TYR B OH  1 
ATOM   4256 N N   . LEU B 1 202 ? 107.168 46.520  197.316 1.00 82.88  ? 199 LEU B N   1 
ATOM   4257 C CA  . LEU B 1 202 ? 107.838 47.194  198.421 1.00 74.63  ? 199 LEU B CA  1 
ATOM   4258 C C   . LEU B 1 202 ? 107.647 46.445  199.727 1.00 75.81  ? 199 LEU B C   1 
ATOM   4259 O O   . LEU B 1 202 ? 108.505 46.527  200.612 1.00 73.20  ? 199 LEU B O   1 
ATOM   4260 C CB  . LEU B 1 202 ? 107.324 48.619  198.561 1.00 65.60  ? 199 LEU B CB  1 
ATOM   4261 C CG  . LEU B 1 202 ? 107.921 49.571  197.549 1.00 64.35  ? 199 LEU B CG  1 
ATOM   4262 C CD1 . LEU B 1 202 ? 107.121 50.866  197.501 1.00 69.30  ? 199 LEU B CD1 1 
ATOM   4263 C CD2 . LEU B 1 202 ? 109.359 49.803  197.909 1.00 60.80  ? 199 LEU B CD2 1 
ATOM   4264 N N   . SER B 1 203 ? 106.529 45.725  199.878 1.00 80.36  ? 200 SER B N   1 
ATOM   4265 C CA  . SER B 1 203 ? 106.355 44.889  201.061 1.00 79.71  ? 200 SER B CA  1 
ATOM   4266 C C   . SER B 1 203 ? 107.447 43.828  201.117 1.00 83.20  ? 200 SER B C   1 
ATOM   4267 O O   . SER B 1 203 ? 108.228 43.780  202.077 1.00 82.29  ? 200 SER B O   1 
ATOM   4268 C CB  . SER B 1 203 ? 104.966 44.255  201.066 1.00 89.25  ? 200 SER B CB  1 
ATOM   4269 O OG  . SER B 1 203 ? 103.961 45.218  201.346 1.00 96.51  ? 200 SER B OG  1 
ATOM   4270 N N   . GLN B 1 204 ? 107.531 42.968  200.093 1.00 82.36  ? 201 GLN B N   1 
ATOM   4271 C CA  . GLN B 1 204 ? 108.774 42.228  199.916 1.00 78.76  ? 201 GLN B CA  1 
ATOM   4272 C C   . GLN B 1 204 ? 109.894 43.255  199.799 1.00 80.23  ? 201 GLN B C   1 
ATOM   4273 O O   . GLN B 1 204 ? 109.656 44.406  199.436 1.00 84.46  ? 201 GLN B O   1 
ATOM   4274 C CB  . GLN B 1 204 ? 108.721 41.294  198.702 1.00 77.94  ? 201 GLN B CB  1 
ATOM   4275 C CG  . GLN B 1 204 ? 108.006 41.846  197.482 1.00 87.27  ? 201 GLN B CG  1 
ATOM   4276 C CD  . GLN B 1 204 ? 107.812 40.811  196.365 1.00 94.07  ? 201 GLN B CD  1 
ATOM   4277 O OE1 . GLN B 1 204 ? 106.810 40.837  195.644 1.00 89.25  ? 201 GLN B OE1 1 
ATOM   4278 N NE2 . GLN B 1 204 ? 108.774 39.906  196.216 1.00 95.33  ? 201 GLN B NE2 1 
ATOM   4279 N N   . LEU B 1 205 ? 111.110 42.851  200.150 1.00 74.14  ? 202 LEU B N   1 
ATOM   4280 C CA  . LEU B 1 205 ? 112.279 43.734  200.257 1.00 75.09  ? 202 LEU B CA  1 
ATOM   4281 C C   . LEU B 1 205 ? 112.360 44.371  201.641 1.00 71.30  ? 202 LEU B C   1 
ATOM   4282 O O   . LEU B 1 205 ? 113.432 44.834  202.041 1.00 68.91  ? 202 LEU B O   1 
ATOM   4283 C CB  . LEU B 1 205 ? 112.323 44.847  199.193 1.00 72.27  ? 202 LEU B CB  1 
ATOM   4284 C CG  . LEU B 1 205 ? 112.329 44.552  197.694 1.00 70.28  ? 202 LEU B CG  1 
ATOM   4285 C CD1 . LEU B 1 205 ? 111.714 45.724  196.958 1.00 73.29  ? 202 LEU B CD1 1 
ATOM   4286 C CD2 . LEU B 1 205 ? 113.746 44.305  197.217 1.00 64.85  ? 202 LEU B CD2 1 
ATOM   4287 N N   . GLY B 1 206 ? 111.255 44.448  202.375 1.00 71.61  ? 203 GLY B N   1 
ATOM   4288 C CA  . GLY B 1 206 ? 111.345 44.740  203.791 1.00 73.57  ? 203 GLY B CA  1 
ATOM   4289 C C   . GLY B 1 206 ? 110.804 46.065  204.262 1.00 73.18  ? 203 GLY B C   1 
ATOM   4290 O O   . GLY B 1 206 ? 111.023 46.415  205.435 1.00 74.19  ? 203 GLY B O   1 
ATOM   4291 N N   . PHE B 1 207 ? 110.157 46.838  203.391 1.00 64.79  ? 204 PHE B N   1 
ATOM   4292 C CA  . PHE B 1 207 ? 109.538 48.077  203.833 1.00 59.30  ? 204 PHE B CA  1 
ATOM   4293 C C   . PHE B 1 207 ? 108.477 47.786  204.879 1.00 60.86  ? 204 PHE B C   1 
ATOM   4294 O O   . PHE B 1 207 ? 107.523 47.044  204.626 1.00 63.72  ? 204 PHE B O   1 
ATOM   4295 C CB  . PHE B 1 207 ? 108.936 48.827  202.654 1.00 60.85  ? 204 PHE B CB  1 
ATOM   4296 C CG  . PHE B 1 207 ? 109.926 49.659  201.898 1.00 59.07  ? 204 PHE B CG  1 
ATOM   4297 C CD1 . PHE B 1 207 ? 110.951 49.072  201.193 1.00 59.71  ? 204 PHE B CD1 1 
ATOM   4298 C CD2 . PHE B 1 207 ? 109.830 51.040  201.900 1.00 59.03  ? 204 PHE B CD2 1 
ATOM   4299 C CE1 . PHE B 1 207 ? 111.858 49.838  200.501 1.00 57.42  ? 204 PHE B CE1 1 
ATOM   4300 C CE2 . PHE B 1 207 ? 110.739 51.813  201.213 1.00 59.20  ? 204 PHE B CE2 1 
ATOM   4301 C CZ  . PHE B 1 207 ? 111.754 51.208  200.508 1.00 60.12  ? 204 PHE B CZ  1 
ATOM   4302 N N   . ASP B 1 208 ? 108.669 48.346  206.069 1.00 59.77  ? 205 ASP B N   1 
ATOM   4303 C CA  . ASP B 1 208 ? 107.723 48.096  207.144 1.00 60.23  ? 205 ASP B CA  1 
ATOM   4304 C C   . ASP B 1 208 ? 106.354 48.688  206.826 1.00 62.38  ? 205 ASP B C   1 
ATOM   4305 O O   . ASP B 1 208 ? 105.335 48.176  207.298 1.00 65.84  ? 205 ASP B O   1 
ATOM   4306 C CB  . ASP B 1 208 ? 108.263 48.663  208.458 1.00 60.39  ? 205 ASP B CB  1 
ATOM   4307 C CG  . ASP B 1 208 ? 109.593 48.042  208.869 1.00 69.77  ? 205 ASP B CG  1 
ATOM   4308 O OD1 . ASP B 1 208 ? 110.619 48.345  208.208 1.00 70.02  ? 205 ASP B OD1 1 
ATOM   4309 O OD2 . ASP B 1 208 ? 109.616 47.270  209.864 1.00 73.97  ? 205 ASP B OD2 1 
ATOM   4310 N N   . ALA B 1 209 ? 106.303 49.745  206.015 1.00 59.00  ? 206 ALA B N   1 
ATOM   4311 C CA  . ALA B 1 209 ? 105.043 50.409  205.718 1.00 57.58  ? 206 ALA B CA  1 
ATOM   4312 C C   . ALA B 1 209 ? 105.116 51.042  204.335 1.00 59.19  ? 206 ALA B C   1 
ATOM   4313 O O   . ALA B 1 209 ? 106.147 51.596  203.955 1.00 59.57  ? 206 ALA B O   1 
ATOM   4314 C CB  . ALA B 1 209 ? 104.716 51.466  206.782 1.00 56.09  ? 206 ALA B CB  1 
ATOM   4315 N N   . VAL B 1 210 ? 104.018 50.962  203.590 1.00 57.40  ? 207 VAL B N   1 
ATOM   4316 C CA  . VAL B 1 210 ? 103.944 51.534  202.256 1.00 58.27  ? 207 VAL B CA  1 
ATOM   4317 C C   . VAL B 1 210 ? 102.699 52.404  202.177 1.00 61.90  ? 207 VAL B C   1 
ATOM   4318 O O   . VAL B 1 210 ? 101.633 52.027  202.675 1.00 63.56  ? 207 VAL B O   1 
ATOM   4319 C CB  . VAL B 1 210 ? 103.926 50.439  201.171 1.00 64.83  ? 207 VAL B CB  1 
ATOM   4320 C CG1 . VAL B 1 210 ? 104.097 51.057  199.788 1.00 70.65  ? 207 VAL B CG1 1 
ATOM   4321 C CG2 . VAL B 1 210 ? 104.998 49.403  201.437 1.00 63.20  ? 207 VAL B CG2 1 
ATOM   4322 N N   . ILE B 1 211 ? 102.846 53.587  201.585 1.00 63.32  ? 208 ILE B N   1 
ATOM   4323 C CA  . ILE B 1 211 ? 101.782 54.581  201.495 1.00 64.76  ? 208 ILE B CA  1 
ATOM   4324 C C   . ILE B 1 211 ? 101.360 54.741  200.039 1.00 71.50  ? 208 ILE B C   1 
ATOM   4325 O O   . ILE B 1 211 ? 102.205 54.867  199.143 1.00 71.37  ? 208 ILE B O   1 
ATOM   4326 C CB  . ILE B 1 211 ? 102.233 55.919  202.103 1.00 60.82  ? 208 ILE B CB  1 
ATOM   4327 C CG1 . ILE B 1 211 ? 102.346 55.754  203.608 1.00 60.00  ? 208 ILE B CG1 1 
ATOM   4328 C CG2 . ILE B 1 211 ? 101.265 57.043  201.764 1.00 61.60  ? 208 ILE B CG2 1 
ATOM   4329 C CD1 . ILE B 1 211 ? 102.936 56.947  204.293 1.00 66.39  ? 208 ILE B CD1 1 
ATOM   4330 N N   . ASP B 1 212 ? 100.048 54.754  199.813 1.00 77.99  ? 209 ASP B N   1 
ATOM   4331 C CA  . ASP B 1 212 ? 99.464  54.914  198.486 1.00 82.03  ? 209 ASP B CA  1 
ATOM   4332 C C   . ASP B 1 212 ? 99.344  56.404  198.208 1.00 84.97  ? 209 ASP B C   1 
ATOM   4333 O O   . ASP B 1 212 ? 98.356  57.042  198.562 1.00 88.84  ? 209 ASP B O   1 
ATOM   4334 C CB  . ASP B 1 212 ? 98.107  54.221  198.429 1.00 83.29  ? 209 ASP B CB  1 
ATOM   4335 C CG  . ASP B 1 212 ? 97.566  54.097  197.021 1.00 98.95  ? 209 ASP B CG  1 
ATOM   4336 O OD1 . ASP B 1 212 ? 98.185  54.655  196.084 1.00 97.91  ? 209 ASP B OD1 1 
ATOM   4337 O OD2 . ASP B 1 212 ? 96.516  53.430  196.852 1.00 103.92 ? 209 ASP B OD2 1 
ATOM   4338 N N   . TYR B 1 213 ? 100.357 56.965  197.546 1.00 85.88  ? 210 TYR B N   1 
ATOM   4339 C CA  . TYR B 1 213 ? 100.323 58.385  197.215 1.00 89.93  ? 210 TYR B CA  1 
ATOM   4340 C C   . TYR B 1 213 ? 99.229  58.708  196.216 1.00 94.35  ? 210 TYR B C   1 
ATOM   4341 O O   . TYR B 1 213 ? 98.862  59.879  196.070 1.00 94.65  ? 210 TYR B O   1 
ATOM   4342 C CB  . TYR B 1 213 ? 101.674 58.855  196.676 1.00 90.22  ? 210 TYR B CB  1 
ATOM   4343 C CG  . TYR B 1 213 ? 102.136 58.057  195.491 1.00 95.97  ? 210 TYR B CG  1 
ATOM   4344 C CD1 . TYR B 1 213 ? 101.503 58.174  194.255 1.00 99.54  ? 210 TYR B CD1 1 
ATOM   4345 C CD2 . TYR B 1 213 ? 103.217 57.186  195.600 1.00 94.07  ? 210 TYR B CD2 1 
ATOM   4346 C CE1 . TYR B 1 213 ? 101.915 57.433  193.167 1.00 101.92 ? 210 TYR B CE1 1 
ATOM   4347 C CE2 . TYR B 1 213 ? 103.652 56.451  194.512 1.00 95.42  ? 210 TYR B CE2 1 
ATOM   4348 C CZ  . TYR B 1 213 ? 102.990 56.574  193.300 1.00 101.33 ? 210 TYR B CZ  1 
ATOM   4349 O OH  . TYR B 1 213 ? 103.400 55.849  192.208 1.00 101.72 ? 210 TYR B OH  1 
ATOM   4350 N N   . LYS B 1 214 ? 98.753  57.709  195.474 1.00 96.35  ? 211 LYS B N   1 
ATOM   4351 C CA  . LYS B 1 214 ? 97.666  57.966  194.544 1.00 101.34 ? 211 LYS B CA  1 
ATOM   4352 C C   . LYS B 1 214 ? 96.332  58.070  195.289 1.00 100.71 ? 211 LYS B C   1 
ATOM   4353 O O   . LYS B 1 214 ? 95.489  58.899  194.931 1.00 104.27 ? 211 LYS B O   1 
ATOM   4354 C CB  . LYS B 1 214 ? 97.658  56.900  193.444 1.00 101.90 ? 211 LYS B CB  1 
ATOM   4355 C CG  . LYS B 1 214 ? 97.319  57.461  192.051 1.00 100.18 ? 211 LYS B CG  1 
ATOM   4356 C CD  . LYS B 1 214 ? 97.284  56.363  190.990 1.00 101.76 ? 211 LYS B CD  1 
ATOM   4357 C CE  . LYS B 1 214 ? 96.559  56.785  189.708 1.00 91.58  ? 211 LYS B CE  1 
ATOM   4358 N NZ  . LYS B 1 214 ? 96.319  55.598  188.812 1.00 78.14  ? 211 LYS B NZ  1 
ATOM   4359 N N   . LEU B 1 215 ? 96.127  57.275  196.351 1.00 101.30 ? 212 LEU B N   1 
ATOM   4360 C CA  . LEU B 1 215 ? 94.952  57.489  197.204 1.00 104.79 ? 212 LEU B CA  1 
ATOM   4361 C C   . LEU B 1 215 ? 94.939  58.885  197.806 1.00 102.08 ? 212 LEU B C   1 
ATOM   4362 O O   . LEU B 1 215 ? 93.866  59.460  198.028 1.00 101.38 ? 212 LEU B O   1 
ATOM   4363 C CB  . LEU B 1 215 ? 94.890  56.468  198.348 1.00 97.09  ? 212 LEU B CB  1 
ATOM   4364 C CG  . LEU B 1 215 ? 94.147  55.147  198.171 1.00 96.43  ? 212 LEU B CG  1 
ATOM   4365 C CD1 . LEU B 1 215 ? 94.361  54.288  199.394 1.00 97.21  ? 212 LEU B CD1 1 
ATOM   4366 C CD2 . LEU B 1 215 ? 92.661  55.428  197.979 1.00 89.99  ? 212 LEU B CD2 1 
ATOM   4367 N N   . ALA B 1 216 ? 96.112  59.426  198.109 1.00 103.67 ? 213 ALA B N   1 
ATOM   4368 C CA  . ALA B 1 216 ? 96.242  60.749  198.688 1.00 102.75 ? 213 ALA B CA  1 
ATOM   4369 C C   . ALA B 1 216 ? 96.851  61.726  197.682 1.00 101.40 ? 213 ALA B C   1 
ATOM   4370 O O   . ALA B 1 216 ? 98.002  62.158  197.817 1.00 93.10  ? 213 ALA B O   1 
ATOM   4371 C CB  . ALA B 1 216 ? 97.068  60.667  199.972 1.00 99.19  ? 213 ALA B CB  1 
ATOM   4372 N N   . ASP B 1 217 ? 96.096  62.046  196.625 1.00 103.22 ? 214 ASP B N   1 
ATOM   4373 C CA  . ASP B 1 217 ? 96.501  63.195  195.820 1.00 107.32 ? 214 ASP B CA  1 
ATOM   4374 C C   . ASP B 1 217 ? 96.479  64.466  196.668 1.00 104.18 ? 214 ASP B C   1 
ATOM   4375 O O   . ASP B 1 217 ? 97.298  65.372  196.459 1.00 97.93  ? 214 ASP B O   1 
ATOM   4376 C CB  . ASP B 1 217 ? 95.620  63.345  194.575 1.00 107.07 ? 214 ASP B CB  1 
ATOM   4377 C CG  . ASP B 1 217 ? 96.370  63.998  193.408 1.00 109.28 ? 214 ASP B CG  1 
ATOM   4378 O OD1 . ASP B 1 217 ? 97.156  64.936  193.664 1.00 111.47 ? 214 ASP B OD1 1 
ATOM   4379 O OD2 . ASP B 1 217 ? 96.195  63.560  192.245 1.00 100.04 ? 214 ASP B OD2 1 
ATOM   4380 N N   . ASP B 1 218 ? 95.530  64.552  197.609 1.00 100.46 ? 215 ASP B N   1 
ATOM   4381 C CA  . ASP B 1 218 ? 95.441  65.654  198.563 1.00 100.90 ? 215 ASP B CA  1 
ATOM   4382 C C   . ASP B 1 218 ? 96.416  65.452  199.726 1.00 96.46  ? 215 ASP B C   1 
ATOM   4383 O O   . ASP B 1 218 ? 96.729  64.328  200.120 1.00 96.44  ? 215 ASP B O   1 
ATOM   4384 C CB  . ASP B 1 218 ? 94.004  65.824  199.083 1.00 101.43 ? 215 ASP B CB  1 
ATOM   4385 C CG  . ASP B 1 218 ? 93.419  64.546  199.683 1.00 104.98 ? 215 ASP B CG  1 
ATOM   4386 O OD1 . ASP B 1 218 ? 93.530  63.467  199.053 1.00 104.48 ? 215 ASP B OD1 1 
ATOM   4387 O OD2 . ASP B 1 218 ? 92.832  64.632  200.788 1.00 102.45 ? 215 ASP B OD2 1 
ATOM   4388 N N   . ALA B 1 219 ? 96.879  66.568  200.291 1.00 93.32  ? 216 ALA B N   1 
ATOM   4389 C CA  . ALA B 1 219 ? 97.870  66.544  201.360 1.00 86.65  ? 216 ALA B CA  1 
ATOM   4390 C C   . ALA B 1 219 ? 97.276  66.221  202.724 1.00 94.14  ? 216 ALA B C   1 
ATOM   4391 O O   . ALA B 1 219 ? 98.025  65.882  203.654 1.00 91.42  ? 216 ALA B O   1 
ATOM   4392 C CB  . ALA B 1 219 ? 98.616  67.882  201.413 1.00 80.88  ? 216 ALA B CB  1 
ATOM   4393 N N   . ASP B 1 220 ? 95.960  66.344  202.882 1.00 95.90  ? 217 ASP B N   1 
ATOM   4394 C CA  . ASP B 1 220 ? 95.360  66.032  204.173 1.00 93.55  ? 217 ASP B CA  1 
ATOM   4395 C C   . ASP B 1 220 ? 95.427  64.537  204.475 1.00 94.44  ? 217 ASP B C   1 
ATOM   4396 O O   . ASP B 1 220 ? 95.918  64.135  205.539 1.00 88.85  ? 217 ASP B O   1 
ATOM   4397 C CB  . ASP B 1 220 ? 93.922  66.530  204.206 1.00 92.58  ? 217 ASP B CB  1 
ATOM   4398 C CG  . ASP B 1 220 ? 93.514  66.973  205.573 1.00 97.06  ? 217 ASP B CG  1 
ATOM   4399 O OD1 . ASP B 1 220 ? 94.374  67.569  206.254 1.00 95.79  ? 217 ASP B OD1 1 
ATOM   4400 O OD2 . ASP B 1 220 ? 92.350  66.726  205.966 1.00 111.16 ? 217 ASP B OD2 1 
ATOM   4401 N N   . LYS B 1 221 ? 94.912  63.694  203.569 1.00 91.52  ? 218 LYS B N   1 
ATOM   4402 C CA  . LYS B 1 221 ? 95.058  62.252  203.759 1.00 89.77  ? 218 LYS B CA  1 
ATOM   4403 C C   . LYS B 1 221 ? 96.504  61.802  203.665 1.00 83.15  ? 218 LYS B C   1 
ATOM   4404 O O   . LYS B 1 221 ? 96.833  60.724  204.175 1.00 78.59  ? 218 LYS B O   1 
ATOM   4405 C CB  . LYS B 1 221 ? 94.220  61.449  202.760 1.00 99.92  ? 218 LYS B CB  1 
ATOM   4406 C CG  . LYS B 1 221 ? 92.719  61.533  202.985 1.00 107.36 ? 218 LYS B CG  1 
ATOM   4407 C CD  . LYS B 1 221 ? 92.029  60.302  202.403 1.00 103.89 ? 218 LYS B CD  1 
ATOM   4408 C CE  . LYS B 1 221 ? 90.559  60.236  202.787 1.00 98.01  ? 218 LYS B CE  1 
ATOM   4409 N NZ  . LYS B 1 221 ? 89.932  59.021  202.197 1.00 100.24 ? 218 LYS B NZ  1 
ATOM   4410 N N   . MET B 1 222 ? 97.350  62.582  202.987 1.00 78.89  ? 219 MET B N   1 
ATOM   4411 C CA  . MET B 1 222 ? 98.773  62.279  202.932 1.00 76.40  ? 219 MET B CA  1 
ATOM   4412 C C   . MET B 1 222 ? 99.461  62.522  204.272 1.00 79.11  ? 219 MET B C   1 
ATOM   4413 O O   . MET B 1 222 ? 100.302 61.722  204.699 1.00 77.69  ? 219 MET B O   1 
ATOM   4414 C CB  . MET B 1 222 ? 99.426  63.125  201.845 1.00 80.14  ? 219 MET B CB  1 
ATOM   4415 C CG  . MET B 1 222 ? 100.911 62.905  201.733 1.00 77.04  ? 219 MET B CG  1 
ATOM   4416 S SD  . MET B 1 222 ? 101.251 61.223  201.206 1.00 93.30  ? 219 MET B SD  1 
ATOM   4417 C CE  . MET B 1 222 ? 100.570 61.233  199.549 1.00 84.23  ? 219 MET B CE  1 
ATOM   4418 N N   . ARG B 1 223 ? 99.115  63.604  204.962 1.00 75.62  ? 220 ARG B N   1 
ATOM   4419 C CA  . ARG B 1 223 ? 99.723  63.826  206.266 1.00 77.22  ? 220 ARG B CA  1 
ATOM   4420 C C   . ARG B 1 223 ? 99.205  62.839  207.310 1.00 78.31  ? 220 ARG B C   1 
ATOM   4421 O O   . ARG B 1 223 ? 99.883  62.597  208.316 1.00 78.66  ? 220 ARG B O   1 
ATOM   4422 C CB  . ARG B 1 223 ? 99.508  65.280  206.679 1.00 84.15  ? 220 ARG B CB  1 
ATOM   4423 C CG  . ARG B 1 223 ? 100.387 65.772  207.826 1.00 80.52  ? 220 ARG B CG  1 
ATOM   4424 C CD  . ARG B 1 223 ? 100.034 67.203  208.213 1.00 79.55  ? 220 ARG B CD  1 
ATOM   4425 N NE  . ARG B 1 223 ? 99.572  67.961  207.054 1.00 84.61  ? 220 ARG B NE  1 
ATOM   4426 C CZ  . ARG B 1 223 ? 98.308  68.295  206.818 1.00 94.90  ? 220 ARG B CZ  1 
ATOM   4427 N NH1 . ARG B 1 223 ? 97.335  67.975  207.662 1.00 97.05  ? 220 ARG B NH1 1 
ATOM   4428 N NH2 . ARG B 1 223 ? 98.010  68.955  205.701 1.00 88.78  ? 220 ARG B NH2 1 
ATOM   4429 N N   . GLU B 1 224 ? 98.019  62.268  207.084 1.00 79.66  ? 221 GLU B N   1 
ATOM   4430 C CA  . GLU B 1 224 ? 97.442  61.270  207.977 1.00 75.87  ? 221 GLU B CA  1 
ATOM   4431 C C   . GLU B 1 224 ? 98.075  59.902  207.763 1.00 73.00  ? 221 GLU B C   1 
ATOM   4432 O O   . GLU B 1 224 ? 98.422  59.205  208.726 1.00 66.06  ? 221 GLU B O   1 
ATOM   4433 C CB  . GLU B 1 224 ? 95.938  61.184  207.746 1.00 81.89  ? 221 GLU B CB  1 
ATOM   4434 C CG  . GLU B 1 224 ? 95.238  60.512  208.871 1.00 80.55  ? 221 GLU B CG  1 
ATOM   4435 C CD  . GLU B 1 224 ? 95.537  61.227  210.157 1.00 88.50  ? 221 GLU B CD  1 
ATOM   4436 O OE1 . GLU B 1 224 ? 95.331  62.463  210.180 1.00 86.60  ? 221 GLU B OE1 1 
ATOM   4437 O OE2 . GLU B 1 224 ? 96.007  60.573  211.123 1.00 89.68  ? 221 GLU B OE2 1 
ATOM   4438 N N   . ALA B 1 225 ? 98.179  59.489  206.496 1.00 75.31  ? 222 ALA B N   1 
ATOM   4439 C CA  . ALA B 1 225 ? 98.873  58.252  206.155 1.00 70.71  ? 222 ALA B CA  1 
ATOM   4440 C C   . ALA B 1 225 ? 100.281 58.220  206.735 1.00 68.36  ? 222 ALA B C   1 
ATOM   4441 O O   . ALA B 1 225 ? 100.730 57.176  207.220 1.00 68.27  ? 222 ALA B O   1 
ATOM   4442 C CB  . ALA B 1 225 ? 98.905  58.079  204.639 1.00 60.51  ? 222 ALA B CB  1 
ATOM   4443 N N   . LEU B 1 226 ? 100.984 59.361  206.711 1.00 66.64  ? 223 LEU B N   1 
ATOM   4444 C CA  . LEU B 1 226 ? 102.328 59.434  207.279 1.00 62.72  ? 223 LEU B CA  1 
ATOM   4445 C C   . LEU B 1 226 ? 102.305 59.348  208.798 1.00 70.52  ? 223 LEU B C   1 
ATOM   4446 O O   . LEU B 1 226 ? 103.168 58.691  209.400 1.00 64.30  ? 223 LEU B O   1 
ATOM   4447 C CB  . LEU B 1 226 ? 103.006 60.725  206.871 1.00 61.69  ? 223 LEU B CB  1 
ATOM   4448 C CG  . LEU B 1 226 ? 103.795 60.674  205.581 1.00 67.42  ? 223 LEU B CG  1 
ATOM   4449 C CD1 . LEU B 1 226 ? 104.395 62.036  205.393 1.00 64.47  ? 223 LEU B CD1 1 
ATOM   4450 C CD2 . LEU B 1 226 ? 104.861 59.615  205.650 1.00 59.72  ? 223 LEU B CD2 1 
ATOM   4451 N N   . ARG B 1 227 ? 101.349 60.040  209.436 1.00 73.89  ? 224 ARG B N   1 
ATOM   4452 C CA  . ARG B 1 227 ? 101.210 59.943  210.886 1.00 69.72  ? 224 ARG B CA  1 
ATOM   4453 C C   . ARG B 1 227 ? 101.014 58.494  211.307 1.00 67.61  ? 224 ARG B C   1 
ATOM   4454 O O   . ARG B 1 227 ? 101.572 58.052  212.316 1.00 63.30  ? 224 ARG B O   1 
ATOM   4455 C CB  . ARG B 1 227 ? 100.056 60.827  211.361 1.00 69.17  ? 224 ARG B CB  1 
ATOM   4456 C CG  . ARG B 1 227 ? 100.523 62.072  212.090 1.00 74.49  ? 224 ARG B CG  1 
ATOM   4457 C CD  . ARG B 1 227 ? 99.386  62.934  212.644 1.00 81.01  ? 224 ARG B CD  1 
ATOM   4458 N NE  . ARG B 1 227 ? 98.399  63.261  211.619 1.00 84.53  ? 224 ARG B NE  1 
ATOM   4459 C CZ  . ARG B 1 227 ? 98.451  64.342  210.848 1.00 83.37  ? 224 ARG B CZ  1 
ATOM   4460 N NH1 . ARG B 1 227 ? 99.420  65.238  210.974 1.00 82.47  ? 224 ARG B NH1 1 
ATOM   4461 N NH2 . ARG B 1 227 ? 97.514  64.527  209.922 1.00 82.46  ? 224 ARG B NH2 1 
ATOM   4462 N N   . GLU B 1 228 ? 100.290 57.715  210.501 1.00 69.72  ? 225 GLU B N   1 
ATOM   4463 C CA  . GLU B 1 228 ? 100.088 56.319  210.860 1.00 67.91  ? 225 GLU B CA  1 
ATOM   4464 C C   . GLU B 1 228 ? 101.319 55.474  210.547 1.00 66.44  ? 225 GLU B C   1 
ATOM   4465 O O   . GLU B 1 228 ? 101.728 54.652  211.373 1.00 64.40  ? 225 GLU B O   1 
ATOM   4466 C CB  . GLU B 1 228 ? 98.858  55.764  210.140 1.00 67.85  ? 225 GLU B CB  1 
ATOM   4467 C CG  . GLU B 1 228 ? 98.303  54.509  210.794 1.00 70.03  ? 225 GLU B CG  1 
ATOM   4468 C CD  . GLU B 1 228 ? 97.103  53.911  210.066 1.00 83.49  ? 225 GLU B CD  1 
ATOM   4469 O OE1 . GLU B 1 228 ? 96.352  54.657  209.389 1.00 85.85  ? 225 GLU B OE1 1 
ATOM   4470 O OE2 . GLU B 1 228 ? 96.917  52.677  210.176 1.00 84.49  ? 225 GLU B OE2 1 
ATOM   4471 N N   . ALA B 1 229 ? 101.950 55.685  209.390 1.00 63.64  ? 226 ALA B N   1 
ATOM   4472 C CA  . ALA B 1 229 ? 103.108 54.871  209.035 1.00 60.97  ? 226 ALA B CA  1 
ATOM   4473 C C   . ALA B 1 229 ? 104.322 55.212  209.889 1.00 63.53  ? 226 ALA B C   1 
ATOM   4474 O O   . ALA B 1 229 ? 105.112 54.325  210.240 1.00 57.93  ? 226 ALA B O   1 
ATOM   4475 C CB  . ALA B 1 229 ? 103.431 55.033  207.556 1.00 58.70  ? 226 ALA B CB  1 
ATOM   4476 N N   . ALA B 1 230 ? 104.493 56.494  210.218 1.00 65.47  ? 227 ALA B N   1 
ATOM   4477 C CA  . ALA B 1 230 ? 105.602 56.980  211.033 1.00 63.03  ? 227 ALA B CA  1 
ATOM   4478 C C   . ALA B 1 230 ? 105.011 57.556  212.308 1.00 66.90  ? 227 ALA B C   1 
ATOM   4479 O O   . ALA B 1 230 ? 104.874 58.781  212.439 1.00 65.22  ? 227 ALA B O   1 
ATOM   4480 C CB  . ALA B 1 230 ? 106.420 58.044  210.306 1.00 60.98  ? 227 ALA B CB  1 
ATOM   4481 N N   . PRO B 1 231 ? 104.657 56.705  213.273 1.00 68.45  ? 228 PRO B N   1 
ATOM   4482 C CA  . PRO B 1 231 ? 103.985 57.207  214.472 1.00 63.34  ? 228 PRO B CA  1 
ATOM   4483 C C   . PRO B 1 231 ? 104.887 58.027  215.347 1.00 63.62  ? 228 PRO B C   1 
ATOM   4484 O O   . PRO B 1 231 ? 104.380 58.808  216.157 1.00 66.70  ? 228 PRO B O   1 
ATOM   4485 C CB  . PRO B 1 231 ? 103.544 55.927  215.181 1.00 62.01  ? 228 PRO B CB  1 
ATOM   4486 C CG  . PRO B 1 231 ? 104.572 54.954  214.810 1.00 67.91  ? 228 PRO B CG  1 
ATOM   4487 C CD  . PRO B 1 231 ? 104.926 55.262  213.372 1.00 71.62  ? 228 PRO B CD  1 
ATOM   4488 N N   . ASP B 1 232 ? 106.205 57.896  215.200 1.00 65.28  ? 229 ASP B N   1 
ATOM   4489 C CA  . ASP B 1 232 ? 107.157 58.565  216.074 1.00 68.44  ? 229 ASP B CA  1 
ATOM   4490 C C   . ASP B 1 232 ? 107.918 59.699  215.387 1.00 66.58  ? 229 ASP B C   1 
ATOM   4491 O O   . ASP B 1 232 ? 108.798 60.303  216.008 1.00 68.46  ? 229 ASP B O   1 
ATOM   4492 C CB  . ASP B 1 232 ? 108.144 57.541  216.625 1.00 68.39  ? 229 ASP B CB  1 
ATOM   4493 C CG  . ASP B 1 232 ? 107.490 56.549  217.554 1.00 81.16  ? 229 ASP B CG  1 
ATOM   4494 O OD1 . ASP B 1 232 ? 106.448 56.898  218.148 1.00 89.32  ? 229 ASP B OD1 1 
ATOM   4495 O OD2 . ASP B 1 232 ? 108.009 55.417  217.688 1.00 88.28  ? 229 ASP B OD2 1 
ATOM   4496 N N   . GLY B 1 233 ? 107.589 60.027  214.148 1.00 61.40  ? 230 GLY B N   1 
ATOM   4497 C CA  . GLY B 1 233 ? 108.222 61.137  213.473 1.00 56.42  ? 230 GLY B CA  1 
ATOM   4498 C C   . GLY B 1 233 ? 109.245 60.658  212.467 1.00 57.81  ? 230 GLY B C   1 
ATOM   4499 O O   . GLY B 1 233 ? 109.726 59.527  212.513 1.00 63.65  ? 230 GLY B O   1 
ATOM   4500 N N   . VAL B 1 234 ? 109.580 61.521  211.531 1.00 53.17  ? 231 VAL B N   1 
ATOM   4501 C CA  . VAL B 1 234 ? 110.540 61.146  210.499 1.00 58.85  ? 231 VAL B CA  1 
ATOM   4502 C C   . VAL B 1 234 ? 111.926 61.612  210.916 1.00 53.92  ? 231 VAL B C   1 
ATOM   4503 O O   . VAL B 1 234 ? 112.109 62.751  211.359 1.00 52.70  ? 231 VAL B O   1 
ATOM   4504 C CB  . VAL B 1 234 ? 110.137 61.702  209.121 1.00 57.13  ? 231 VAL B CB  1 
ATOM   4505 C CG1 . VAL B 1 234 ? 111.167 61.290  208.058 1.00 46.37  ? 231 VAL B CG1 1 
ATOM   4506 C CG2 . VAL B 1 234 ? 108.754 61.176  208.757 1.00 52.01  ? 231 VAL B CG2 1 
ATOM   4507 N N   . ASP B 1 235 ? 112.896 60.711  210.819 1.00 52.78  ? 232 ASP B N   1 
ATOM   4508 C CA  . ASP B 1 235 ? 114.278 61.047  211.092 1.00 50.90  ? 232 ASP B CA  1 
ATOM   4509 C C   . ASP B 1 235 ? 115.101 61.171  209.829 1.00 48.37  ? 232 ASP B C   1 
ATOM   4510 O O   . ASP B 1 235 ? 115.970 62.040  209.736 1.00 45.03  ? 232 ASP B O   1 
ATOM   4511 C CB  . ASP B 1 235 ? 114.897 59.975  211.984 1.00 48.09  ? 232 ASP B CB  1 
ATOM   4512 C CG  . ASP B 1 235 ? 114.417 60.072  213.390 1.00 54.47  ? 232 ASP B CG  1 
ATOM   4513 O OD1 . ASP B 1 235 ? 114.603 61.147  214.015 1.00 51.76  ? 232 ASP B OD1 1 
ATOM   4514 O OD2 . ASP B 1 235 ? 113.832 59.075  213.862 1.00 60.63  ? 232 ASP B OD2 1 
ATOM   4515 N N   . LYS B 1 236 ? 114.802 60.362  208.832 1.00 49.15  ? 233 LYS B N   1 
ATOM   4516 C CA  . LYS B 1 236 ? 115.511 60.448  207.575 1.00 49.54  ? 233 LYS B CA  1 
ATOM   4517 C C   . LYS B 1 236 ? 114.477 60.388  206.469 1.00 49.31  ? 233 LYS B C   1 
ATOM   4518 O O   . LYS B 1 236 ? 113.581 59.540  206.501 1.00 50.74  ? 233 LYS B O   1 
ATOM   4519 C CB  . LYS B 1 236 ? 116.558 59.331  207.458 1.00 52.39  ? 233 LYS B CB  1 
ATOM   4520 C CG  . LYS B 1 236 ? 117.416 59.137  208.737 1.00 51.91  ? 233 LYS B CG  1 
ATOM   4521 C CD  . LYS B 1 236 ? 118.567 60.145  208.796 1.00 51.36  ? 233 LYS B CD  1 
ATOM   4522 C CE  . LYS B 1 236 ? 118.931 60.550  210.224 1.00 51.17  ? 233 LYS B CE  1 
ATOM   4523 N NZ  . LYS B 1 236 ? 119.561 59.469  211.004 1.00 56.23  ? 233 LYS B NZ  1 
ATOM   4524 N N   . TYR B 1 237 ? 114.587 61.331  205.532 1.00 48.70  ? 234 TYR B N   1 
ATOM   4525 C CA  . TYR B 1 237 ? 113.733 61.437  204.356 1.00 45.27  ? 234 TYR B CA  1 
ATOM   4526 C C   . TYR B 1 237 ? 114.618 61.398  203.120 1.00 48.86  ? 234 TYR B C   1 
ATOM   4527 O O   . TYR B 1 237 ? 115.454 62.287  202.918 1.00 49.12  ? 234 TYR B O   1 
ATOM   4528 C CB  . TYR B 1 237 ? 112.925 62.733  204.384 1.00 40.81  ? 234 TYR B CB  1 
ATOM   4529 C CG  . TYR B 1 237 ? 111.924 62.859  203.281 1.00 43.67  ? 234 TYR B CG  1 
ATOM   4530 C CD1 . TYR B 1 237 ? 111.453 61.743  202.610 1.00 48.48  ? 234 TYR B CD1 1 
ATOM   4531 C CD2 . TYR B 1 237 ? 111.440 64.098  202.903 1.00 47.06  ? 234 TYR B CD2 1 
ATOM   4532 C CE1 . TYR B 1 237 ? 110.525 61.860  201.576 1.00 47.19  ? 234 TYR B CE1 1 
ATOM   4533 C CE2 . TYR B 1 237 ? 110.506 64.220  201.884 1.00 48.25  ? 234 TYR B CE2 1 
ATOM   4534 C CZ  . TYR B 1 237 ? 110.062 63.102  201.228 1.00 45.68  ? 234 TYR B CZ  1 
ATOM   4535 O OH  . TYR B 1 237 ? 109.151 63.245  200.222 1.00 48.70  ? 234 TYR B OH  1 
ATOM   4536 N N   . PHE B 1 238 ? 114.452 60.363  202.309 1.00 49.76  ? 235 PHE B N   1 
ATOM   4537 C CA  . PHE B 1 238 ? 115.073 60.294  200.997 1.00 46.58  ? 235 PHE B CA  1 
ATOM   4538 C C   . PHE B 1 238 ? 113.992 60.614  199.985 1.00 48.70  ? 235 PHE B C   1 
ATOM   4539 O O   . PHE B 1 238 ? 113.062 59.824  199.801 1.00 49.53  ? 235 PHE B O   1 
ATOM   4540 C CB  . PHE B 1 238 ? 115.670 58.927  200.727 1.00 47.58  ? 235 PHE B CB  1 
ATOM   4541 C CG  . PHE B 1 238 ? 116.518 58.905  199.524 1.00 46.19  ? 235 PHE B CG  1 
ATOM   4542 C CD1 . PHE B 1 238 ? 117.835 59.281  199.607 1.00 45.85  ? 235 PHE B CD1 1 
ATOM   4543 C CD2 . PHE B 1 238 ? 115.991 58.565  198.294 1.00 51.79  ? 235 PHE B CD2 1 
ATOM   4544 C CE1 . PHE B 1 238 ? 118.638 59.272  198.498 1.00 48.42  ? 235 PHE B CE1 1 
ATOM   4545 C CE2 . PHE B 1 238 ? 116.781 58.570  197.167 1.00 52.55  ? 235 PHE B CE2 1 
ATOM   4546 C CZ  . PHE B 1 238 ? 118.110 58.925  197.271 1.00 52.89  ? 235 PHE B CZ  1 
ATOM   4547 N N   . ASP B 1 239 ? 114.102 61.778  199.348 1.00 50.89  ? 236 ASP B N   1 
ATOM   4548 C CA  . ASP B 1 239 ? 113.019 62.373  198.571 1.00 51.45  ? 236 ASP B CA  1 
ATOM   4549 C C   . ASP B 1 239 ? 113.354 62.322  197.080 1.00 50.33  ? 236 ASP B C   1 
ATOM   4550 O O   . ASP B 1 239 ? 114.316 62.953  196.636 1.00 51.09  ? 236 ASP B O   1 
ATOM   4551 C CB  . ASP B 1 239 ? 112.780 63.814  199.035 1.00 49.58  ? 236 ASP B CB  1 
ATOM   4552 C CG  . ASP B 1 239 ? 111.532 64.447  198.422 1.00 54.46  ? 236 ASP B CG  1 
ATOM   4553 O OD1 . ASP B 1 239 ? 110.622 63.699  198.004 1.00 55.97  ? 236 ASP B OD1 1 
ATOM   4554 O OD2 . ASP B 1 239 ? 111.447 65.702  198.377 1.00 55.36  ? 236 ASP B OD2 1 
ATOM   4555 N N   . SER B 1 240 ? 112.554 61.571  196.313 1.00 52.81  ? 237 SER B N   1 
ATOM   4556 C CA  . SER B 1 240 ? 112.611 61.564  194.855 1.00 55.83  ? 237 SER B CA  1 
ATOM   4557 C C   . SER B 1 240 ? 111.370 62.145  194.200 1.00 54.65  ? 237 SER B C   1 
ATOM   4558 O O   . SER B 1 240 ? 111.406 62.413  192.999 1.00 55.15  ? 237 SER B O   1 
ATOM   4559 C CB  . SER B 1 240 ? 112.813 60.140  194.316 1.00 56.04  ? 237 SER B CB  1 
ATOM   4560 O OG  . SER B 1 240 ? 114.135 59.689  194.516 1.00 59.91  ? 237 SER B OG  1 
ATOM   4561 N N   . ILE B 1 241 ? 110.310 62.387  194.966 1.00 54.92  ? 238 ILE B N   1 
ATOM   4562 C CA  . ILE B 1 241 ? 108.987 62.721  194.451 1.00 53.37  ? 238 ILE B CA  1 
ATOM   4563 C C   . ILE B 1 241 ? 108.670 64.197  194.635 1.00 52.11  ? 238 ILE B C   1 
ATOM   4564 O O   . ILE B 1 241 ? 108.146 64.840  193.732 1.00 59.41  ? 238 ILE B O   1 
ATOM   4565 C CB  . ILE B 1 241 ? 107.904 61.847  195.118 1.00 62.36  ? 238 ILE B CB  1 
ATOM   4566 C CG1 . ILE B 1 241 ? 108.085 60.380  194.732 1.00 65.11  ? 238 ILE B CG1 1 
ATOM   4567 C CG2 . ILE B 1 241 ? 106.516 62.392  194.856 1.00 60.51  ? 238 ILE B CG2 1 
ATOM   4568 C CD1 . ILE B 1 241 ? 108.459 60.184  193.323 1.00 70.05  ? 238 ILE B CD1 1 
ATOM   4569 N N   . GLY B 1 242 ? 108.929 64.737  195.812 1.00 48.07  ? 239 GLY B N   1 
ATOM   4570 C CA  . GLY B 1 242 ? 108.554 66.111  196.070 1.00 50.69  ? 239 GLY B CA  1 
ATOM   4571 C C   . GLY B 1 242 ? 107.062 66.254  196.323 1.00 54.58  ? 239 GLY B C   1 
ATOM   4572 O O   . GLY B 1 242 ? 106.417 65.400  196.935 1.00 56.13  ? 239 GLY B O   1 
ATOM   4573 N N   . GLY B 1 243 ? 106.524 67.386  195.885 1.00 55.09  ? 240 GLY B N   1 
ATOM   4574 C CA  . GLY B 1 243 ? 105.088 67.597  195.915 1.00 58.80  ? 240 GLY B CA  1 
ATOM   4575 C C   . GLY B 1 243 ? 104.481 67.447  197.295 1.00 57.56  ? 240 GLY B C   1 
ATOM   4576 O O   . GLY B 1 243 ? 105.123 67.694  198.315 1.00 59.13  ? 240 GLY B O   1 
ATOM   4577 N N   . SER B 1 244 ? 103.236 66.963  197.330 1.00 57.66  ? 241 SER B N   1 
ATOM   4578 C CA  . SER B 1 244 ? 102.481 67.003  198.577 1.00 60.81  ? 241 SER B CA  1 
ATOM   4579 C C   . SER B 1 244 ? 102.962 65.965  199.587 1.00 59.58  ? 241 SER B C   1 
ATOM   4580 O O   . SER B 1 244 ? 102.562 66.036  200.756 1.00 57.39  ? 241 SER B O   1 
ATOM   4581 C CB  . SER B 1 244 ? 100.982 66.856  198.300 1.00 62.08  ? 241 SER B CB  1 
ATOM   4582 O OG  . SER B 1 244 ? 100.562 65.514  198.382 1.00 71.62  ? 241 SER B OG  1 
ATOM   4583 N N   . VAL B 1 245 ? 103.783 64.999  199.159 1.00 62.60  ? 242 VAL B N   1 
ATOM   4584 C CA  . VAL B 1 245 ? 104.359 64.022  200.085 1.00 58.43  ? 242 VAL B CA  1 
ATOM   4585 C C   . VAL B 1 245 ? 105.468 64.655  200.904 1.00 54.59  ? 242 VAL B C   1 
ATOM   4586 O O   . VAL B 1 245 ? 105.583 64.421  202.110 1.00 52.76  ? 242 VAL B O   1 
ATOM   4587 C CB  . VAL B 1 245 ? 104.909 62.803  199.323 1.00 60.10  ? 242 VAL B CB  1 
ATOM   4588 C CG1 . VAL B 1 245 ? 105.103 61.638  200.266 1.00 44.10  ? 242 VAL B CG1 1 
ATOM   4589 C CG2 . VAL B 1 245 ? 104.038 62.460  198.076 1.00 75.26  ? 242 VAL B CG2 1 
ATOM   4590 N N   . THR B 1 246 ? 106.323 65.439  200.252 1.00 56.51  ? 243 THR B N   1 
ATOM   4591 C CA  . THR B 1 246 ? 107.368 66.149  200.975 1.00 54.75  ? 243 THR B CA  1 
ATOM   4592 C C   . THR B 1 246 ? 106.766 67.198  201.899 1.00 54.61  ? 243 THR B C   1 
ATOM   4593 O O   . THR B 1 246 ? 107.241 67.387  203.025 1.00 56.51  ? 243 THR B O   1 
ATOM   4594 C CB  . THR B 1 246 ? 108.343 66.773  199.983 1.00 49.50  ? 243 THR B CB  1 
ATOM   4595 O OG1 . THR B 1 246 ? 108.938 65.730  199.214 1.00 46.00  ? 243 THR B OG1 1 
ATOM   4596 C CG2 . THR B 1 246 ? 109.443 67.512  200.710 1.00 49.87  ? 243 THR B CG2 1 
ATOM   4597 N N   . ASP B 1 247 ? 105.697 67.863  201.453 1.00 54.14  ? 244 ASP B N   1 
ATOM   4598 C CA  . ASP B 1 247 ? 104.942 68.745  202.334 1.00 54.61  ? 244 ASP B CA  1 
ATOM   4599 C C   . ASP B 1 247 ? 104.492 68.032  203.597 1.00 57.42  ? 244 ASP B C   1 
ATOM   4600 O O   . ASP B 1 247 ? 104.555 68.593  204.696 1.00 58.54  ? 244 ASP B O   1 
ATOM   4601 C CB  . ASP B 1 247 ? 103.723 69.282  201.603 1.00 54.77  ? 244 ASP B CB  1 
ATOM   4602 C CG  . ASP B 1 247 ? 104.090 70.104  200.416 1.00 58.89  ? 244 ASP B CG  1 
ATOM   4603 O OD1 . ASP B 1 247 ? 105.300 70.293  200.178 1.00 63.55  ? 244 ASP B OD1 1 
ATOM   4604 O OD2 . ASP B 1 247 ? 103.173 70.586  199.729 1.00 63.91  ? 244 ASP B OD2 1 
ATOM   4605 N N   . ALA B 1 248 ? 104.033 66.790  203.456 1.00 57.31  ? 245 ALA B N   1 
ATOM   4606 C CA  . ALA B 1 248 ? 103.589 66.030  204.616 1.00 57.54  ? 245 ALA B CA  1 
ATOM   4607 C C   . ALA B 1 248 ? 104.765 65.656  205.503 1.00 56.98  ? 245 ALA B C   1 
ATOM   4608 O O   . ALA B 1 248 ? 104.693 65.802  206.727 1.00 59.10  ? 245 ALA B O   1 
ATOM   4609 C CB  . ALA B 1 248 ? 102.825 64.793  204.168 1.00 63.88  ? 245 ALA B CB  1 
ATOM   4610 N N   . VAL B 1 249 ? 105.857 65.164  204.901 1.00 57.08  ? 246 VAL B N   1 
ATOM   4611 C CA  . VAL B 1 249 ? 107.016 64.714  205.671 1.00 51.21  ? 246 VAL B CA  1 
ATOM   4612 C C   . VAL B 1 249 ? 107.645 65.865  206.439 1.00 51.82  ? 246 VAL B C   1 
ATOM   4613 O O   . VAL B 1 249 ? 108.156 65.677  207.549 1.00 54.12  ? 246 VAL B O   1 
ATOM   4614 C CB  . VAL B 1 249 ? 108.056 64.030  204.760 1.00 46.91  ? 246 VAL B CB  1 
ATOM   4615 C CG1 . VAL B 1 249 ? 109.322 63.812  205.505 1.00 46.38  ? 246 VAL B CG1 1 
ATOM   4616 C CG2 . VAL B 1 249 ? 107.563 62.700  204.289 1.00 50.12  ? 246 VAL B CG2 1 
ATOM   4617 N N   . PHE B 1 250 ? 107.629 67.071  205.878 1.00 52.83  ? 247 PHE B N   1 
ATOM   4618 C CA  . PHE B 1 250 ? 108.278 68.182  206.571 1.00 55.15  ? 247 PHE B CA  1 
ATOM   4619 C C   . PHE B 1 250 ? 107.517 68.621  207.823 1.00 58.19  ? 247 PHE B C   1 
ATOM   4620 O O   . PHE B 1 250 ? 108.104 69.256  208.709 1.00 54.93  ? 247 PHE B O   1 
ATOM   4621 C CB  . PHE B 1 250 ? 108.472 69.338  205.590 1.00 48.27  ? 247 PHE B CB  1 
ATOM   4622 C CG  . PHE B 1 250 ? 109.816 69.326  204.930 1.00 43.61  ? 247 PHE B CG  1 
ATOM   4623 C CD1 . PHE B 1 250 ? 110.200 68.247  204.134 1.00 45.03  ? 247 PHE B CD1 1 
ATOM   4624 C CD2 . PHE B 1 250 ? 110.689 70.386  205.081 1.00 41.00  ? 247 PHE B CD2 1 
ATOM   4625 C CE1 . PHE B 1 250 ? 111.448 68.217  203.523 1.00 46.37  ? 247 PHE B CE1 1 
ATOM   4626 C CE2 . PHE B 1 250 ? 111.937 70.366  204.476 1.00 42.11  ? 247 PHE B CE2 1 
ATOM   4627 C CZ  . PHE B 1 250 ? 112.324 69.280  203.697 1.00 44.93  ? 247 PHE B CZ  1 
ATOM   4628 N N   . SER B 1 251 ? 106.241 68.260  207.936 1.00 58.16  ? 248 SER B N   1 
ATOM   4629 C CA  . SER B 1 251 ? 105.449 68.564  209.114 1.00 54.15  ? 248 SER B CA  1 
ATOM   4630 C C   . SER B 1 251 ? 105.732 67.624  210.275 1.00 57.34  ? 248 SER B C   1 
ATOM   4631 O O   . SER B 1 251 ? 105.182 67.821  211.365 1.00 59.48  ? 248 SER B O   1 
ATOM   4632 C CB  . SER B 1 251 ? 103.971 68.477  208.758 1.00 58.50  ? 248 SER B CB  1 
ATOM   4633 O OG  . SER B 1 251 ? 103.587 67.117  208.656 1.00 59.53  ? 248 SER B OG  1 
ATOM   4634 N N   . MET B 1 252 ? 106.576 66.619  210.086 1.00 52.27  ? 249 MET B N   1 
ATOM   4635 C CA  . MET B 1 252 ? 106.791 65.641  211.135 1.00 52.55  ? 249 MET B CA  1 
ATOM   4636 C C   . MET B 1 252 ? 108.262 65.279  211.254 1.00 54.58  ? 249 MET B C   1 
ATOM   4637 O O   . MET B 1 252 ? 108.619 64.129  211.534 1.00 56.39  ? 249 MET B O   1 
ATOM   4638 C CB  . MET B 1 252 ? 105.932 64.402  210.901 1.00 52.42  ? 249 MET B CB  1 
ATOM   4639 C CG  . MET B 1 252 ? 105.996 63.835  209.517 1.00 49.69  ? 249 MET B CG  1 
ATOM   4640 S SD  . MET B 1 252 ? 104.766 62.540  209.334 1.00 63.56  ? 249 MET B SD  1 
ATOM   4641 C CE  . MET B 1 252 ? 103.227 63.451  209.493 1.00 64.63  ? 249 MET B CE  1 
ATOM   4642 N N   . LEU B 1 253 ? 109.137 66.260  211.073 1.00 55.66  ? 250 LEU B N   1 
ATOM   4643 C CA  . LEU B 1 253 ? 110.572 66.023  211.161 1.00 53.76  ? 250 LEU B CA  1 
ATOM   4644 C C   . LEU B 1 253 ? 110.973 66.031  212.627 1.00 53.22  ? 250 LEU B C   1 
ATOM   4645 O O   . LEU B 1 253 ? 110.604 66.950  213.365 1.00 53.09  ? 250 LEU B O   1 
ATOM   4646 C CB  . LEU B 1 253 ? 111.346 67.090  210.386 1.00 52.34  ? 250 LEU B CB  1 
ATOM   4647 C CG  . LEU B 1 253 ? 111.123 67.038  208.874 1.00 53.66  ? 250 LEU B CG  1 
ATOM   4648 C CD1 . LEU B 1 253 ? 111.850 68.169  208.179 1.00 43.58  ? 250 LEU B CD1 1 
ATOM   4649 C CD2 . LEU B 1 253 ? 111.574 65.678  208.372 1.00 49.35  ? 250 LEU B CD2 1 
ATOM   4650 N N   . ASN B 1 254 ? 111.664 64.972  213.056 1.00 50.45  ? 251 ASN B N   1 
ATOM   4651 C CA  . ASN B 1 254 ? 112.222 64.882  214.397 1.00 52.19  ? 251 ASN B CA  1 
ATOM   4652 C C   . ASN B 1 254 ? 113.455 65.789  214.537 1.00 52.98  ? 251 ASN B C   1 
ATOM   4653 O O   . ASN B 1 254 ? 113.989 66.314  213.556 1.00 50.90  ? 251 ASN B O   1 
ATOM   4654 C CB  . ASN B 1 254 ? 112.594 63.437  214.719 1.00 53.76  ? 251 ASN B CB  1 
ATOM   4655 C CG  . ASN B 1 254 ? 111.390 62.535  214.873 1.00 54.01  ? 251 ASN B CG  1 
ATOM   4656 O OD1 . ASN B 1 254 ? 110.322 62.961  215.298 1.00 52.63  ? 251 ASN B OD1 1 
ATOM   4657 N ND2 . ASN B 1 254 ? 111.574 61.263  214.558 1.00 58.09  ? 251 ASN B ND2 1 
ATOM   4658 N N   . VAL B 1 255 ? 113.926 65.971  215.775 1.00 46.35  ? 252 VAL B N   1 
ATOM   4659 C CA  . VAL B 1 255 ? 115.187 66.680  215.945 1.00 50.53  ? 252 VAL B CA  1 
ATOM   4660 C C   . VAL B 1 255 ? 116.310 65.887  215.269 1.00 50.87  ? 252 VAL B C   1 
ATOM   4661 O O   . VAL B 1 255 ? 116.298 64.648  215.237 1.00 47.92  ? 252 VAL B O   1 
ATOM   4662 C CB  . VAL B 1 255 ? 115.493 66.941  217.434 1.00 50.27  ? 252 VAL B CB  1 
ATOM   4663 C CG1 . VAL B 1 255 ? 116.888 67.543  217.600 1.00 43.39  ? 252 VAL B CG1 1 
ATOM   4664 C CG2 . VAL B 1 255 ? 114.478 67.886  218.041 1.00 51.02  ? 252 VAL B CG2 1 
ATOM   4665 N N   . GLY B 1 256 ? 117.254 66.612  214.662 1.00 50.90  ? 253 GLY B N   1 
ATOM   4666 C CA  . GLY B 1 256 ? 118.450 66.026  214.094 1.00 40.80  ? 253 GLY B CA  1 
ATOM   4667 C C   . GLY B 1 256 ? 118.235 65.310  212.797 1.00 43.78  ? 253 GLY B C   1 
ATOM   4668 O O   . GLY B 1 256 ? 119.100 64.544  212.370 1.00 47.57  ? 253 GLY B O   1 
ATOM   4669 N N   . SER B 1 257 ? 117.107 65.547  212.146 1.00 48.32  ? 254 SER B N   1 
ATOM   4670 C CA  . SER B 1 257 ? 116.757 64.799  210.957 1.00 45.78  ? 254 SER B CA  1 
ATOM   4671 C C   . SER B 1 257 ? 117.584 65.245  209.754 1.00 44.05  ? 254 SER B C   1 
ATOM   4672 O O   . SER B 1 257 ? 118.225 66.300  209.741 1.00 45.46  ? 254 SER B O   1 
ATOM   4673 C CB  . SER B 1 257 ? 115.259 64.936  210.678 1.00 48.67  ? 254 SER B CB  1 
ATOM   4674 O OG  . SER B 1 257 ? 114.805 66.261  210.915 1.00 50.57  ? 254 SER B OG  1 
ATOM   4675 N N   . GLN B 1 258 ? 117.568 64.401  208.731 1.00 44.65  ? 255 GLN B N   1 
ATOM   4676 C CA  . GLN B 1 258 ? 118.303 64.645  207.503 1.00 44.91  ? 255 GLN B CA  1 
ATOM   4677 C C   . GLN B 1 258 ? 117.417 64.278  206.320 1.00 50.59  ? 255 GLN B C   1 
ATOM   4678 O O   . GLN B 1 258 ? 116.973 63.127  206.214 1.00 50.08  ? 255 GLN B O   1 
ATOM   4679 C CB  . GLN B 1 258 ? 119.584 63.826  207.477 1.00 44.98  ? 255 GLN B CB  1 
ATOM   4680 C CG  . GLN B 1 258 ? 120.302 63.780  208.769 1.00 44.77  ? 255 GLN B CG  1 
ATOM   4681 C CD  . GLN B 1 258 ? 121.605 63.049  208.644 1.00 49.31  ? 255 GLN B CD  1 
ATOM   4682 O OE1 . GLN B 1 258 ? 121.642 61.835  208.443 1.00 49.54  ? 255 GLN B OE1 1 
ATOM   4683 N NE2 . GLN B 1 258 ? 122.697 63.794  208.735 1.00 51.95  ? 255 GLN B NE2 1 
ATOM   4684 N N   . VAL B 1 259 ? 117.144 65.265  205.441 1.00 46.64  ? 256 VAL B N   1 
ATOM   4685 C CA  . VAL B 1 259 ? 116.491 65.045  204.159 1.00 44.30  ? 256 VAL B CA  1 
ATOM   4686 C C   . VAL B 1 259 ? 117.570 64.924  203.093 1.00 47.41  ? 256 VAL B C   1 
ATOM   4687 O O   . VAL B 1 259 ? 118.617 65.570  203.168 1.00 49.44  ? 256 VAL B O   1 
ATOM   4688 C CB  . VAL B 1 259 ? 115.540 66.202  203.811 1.00 43.58  ? 256 VAL B CB  1 
ATOM   4689 C CG1 . VAL B 1 259 ? 114.710 65.845  202.606 1.00 48.84  ? 256 VAL B CG1 1 
ATOM   4690 C CG2 . VAL B 1 259 ? 114.703 66.558  204.958 1.00 42.12  ? 256 VAL B CG2 1 
ATOM   4691 N N   . ALA B 1 260 ? 117.336 64.086  202.095 1.00 46.24  ? 257 ALA B N   1 
ATOM   4692 C CA  . ALA B 1 260 ? 118.189 64.067  200.908 1.00 49.25  ? 257 ALA B CA  1 
ATOM   4693 C C   . ALA B 1 260 ? 117.260 64.283  199.723 1.00 52.44  ? 257 ALA B C   1 
ATOM   4694 O O   . ALA B 1 260 ? 116.493 63.384  199.368 1.00 53.88  ? 257 ALA B O   1 
ATOM   4695 C CB  . ALA B 1 260 ? 118.983 62.769  200.779 1.00 42.67  ? 257 ALA B CB  1 
ATOM   4696 N N   . VAL B 1 261 ? 117.290 65.483  199.147 1.00 52.92  ? 258 VAL B N   1 
ATOM   4697 C CA  . VAL B 1 261 ? 116.520 65.781  197.939 1.00 52.16  ? 258 VAL B CA  1 
ATOM   4698 C C   . VAL B 1 261 ? 117.278 65.250  196.729 1.00 52.83  ? 258 VAL B C   1 
ATOM   4699 O O   . VAL B 1 261 ? 118.363 65.727  196.399 1.00 52.60  ? 258 VAL B O   1 
ATOM   4700 C CB  . VAL B 1 261 ? 116.250 67.276  197.784 1.00 53.41  ? 258 VAL B CB  1 
ATOM   4701 C CG1 . VAL B 1 261 ? 115.223 67.455  196.720 1.00 55.38  ? 258 VAL B CG1 1 
ATOM   4702 C CG2 . VAL B 1 261 ? 115.800 67.886  199.096 1.00 57.79  ? 258 VAL B CG2 1 
ATOM   4703 N N   . CYS B 1 262 ? 116.701 64.268  196.055 1.00 58.60  ? 259 CYS B N   1 
ATOM   4704 C CA  . CYS B 1 262 ? 117.367 63.598  194.951 1.00 58.12  ? 259 CYS B CA  1 
ATOM   4705 C C   . CYS B 1 262 ? 116.747 63.930  193.601 1.00 59.83  ? 259 CYS B C   1 
ATOM   4706 O O   . CYS B 1 262 ? 117.454 64.334  192.674 1.00 59.09  ? 259 CYS B O   1 
ATOM   4707 C CB  . CYS B 1 262 ? 117.331 62.089  195.215 1.00 57.99  ? 259 CYS B CB  1 
ATOM   4708 S SG  . CYS B 1 262 ? 117.757 61.081  193.827 1.00 70.48  ? 259 CYS B SG  1 
ATOM   4709 N N   . TRP B 1 263 ? 115.423 63.859  193.491 1.00 58.49  ? 260 TRP B N   1 
ATOM   4710 C CA  . TRP B 1 263 ? 114.718 64.339  192.313 1.00 60.19  ? 260 TRP B CA  1 
ATOM   4711 C C   . TRP B 1 263 ? 113.379 64.852  192.817 1.00 58.64  ? 260 TRP B C   1 
ATOM   4712 O O   . TRP B 1 263 ? 113.064 64.724  193.999 1.00 58.72  ? 260 TRP B O   1 
ATOM   4713 C CB  . TRP B 1 263 ? 114.575 63.235  191.249 1.00 65.93  ? 260 TRP B CB  1 
ATOM   4714 C CG  . TRP B 1 263 ? 114.451 63.716  189.797 1.00 69.78  ? 260 TRP B CG  1 
ATOM   4715 C CD1 . TRP B 1 263 ? 115.321 64.528  189.110 1.00 66.47  ? 260 TRP B CD1 1 
ATOM   4716 C CD2 . TRP B 1 263 ? 113.426 63.366  188.865 1.00 67.60  ? 260 TRP B CD2 1 
ATOM   4717 N NE1 . TRP B 1 263 ? 114.884 64.720  187.826 1.00 60.27  ? 260 TRP B NE1 1 
ATOM   4718 C CE2 . TRP B 1 263 ? 113.723 64.016  187.650 1.00 65.02  ? 260 TRP B CE2 1 
ATOM   4719 C CE3 . TRP B 1 263 ? 112.280 62.573  188.941 1.00 66.36  ? 260 TRP B CE3 1 
ATOM   4720 C CZ2 . TRP B 1 263 ? 112.911 63.905  186.533 1.00 65.95  ? 260 TRP B CZ2 1 
ATOM   4721 C CZ3 . TRP B 1 263 ? 111.482 62.458  187.823 1.00 68.47  ? 260 TRP B CZ3 1 
ATOM   4722 C CH2 . TRP B 1 263 ? 111.800 63.119  186.636 1.00 65.67  ? 260 TRP B CH2 1 
ATOM   4723 N N   . GLN B 1 264 ? 112.611 65.496  191.931 1.00 61.41  ? 261 GLN B N   1 
ATOM   4724 C CA  . GLN B 1 264 ? 111.304 66.051  192.290 1.00 56.77  ? 261 GLN B CA  1 
ATOM   4725 C C   . GLN B 1 264 ? 110.314 65.747  191.161 1.00 57.66  ? 261 GLN B C   1 
ATOM   4726 O O   . GLN B 1 264 ? 109.912 66.624  190.403 1.00 57.51  ? 261 GLN B O   1 
ATOM   4727 C CB  . GLN B 1 264 ? 111.378 67.555  192.576 1.00 56.15  ? 261 GLN B CB  1 
ATOM   4728 C CG  . GLN B 1 264 ? 112.243 67.992  193.757 1.00 49.75  ? 261 GLN B CG  1 
ATOM   4729 C CD  . GLN B 1 264 ? 111.529 67.867  195.091 1.00 52.78  ? 261 GLN B CD  1 
ATOM   4730 O OE1 . GLN B 1 264 ? 110.873 68.800  195.545 1.00 52.99  ? 261 GLN B OE1 1 
ATOM   4731 N NE2 . GLN B 1 264 ? 111.714 66.740  195.758 1.00 52.63  ? 261 GLN B NE2 1 
ATOM   4732 N N   . TRP B 1 265 ? 109.924 64.476  191.070 1.00 58.94  ? 262 TRP B N   1 
ATOM   4733 C CA  . TRP B 1 265 ? 109.011 64.021  190.027 1.00 59.14  ? 262 TRP B CA  1 
ATOM   4734 C C   . TRP B 1 265 ? 107.818 64.951  189.901 1.00 63.31  ? 262 TRP B C   1 
ATOM   4735 O O   . TRP B 1 265 ? 107.447 65.358  188.795 1.00 68.33  ? 262 TRP B O   1 
ATOM   4736 C CB  . TRP B 1 265 ? 108.581 62.588  190.340 1.00 61.78  ? 262 TRP B CB  1 
ATOM   4737 C CG  . TRP B 1 265 ? 107.575 61.957  189.442 1.00 70.74  ? 262 TRP B CG  1 
ATOM   4738 C CD1 . TRP B 1 265 ? 106.263 62.305  189.308 1.00 76.66  ? 262 TRP B CD1 1 
ATOM   4739 C CD2 . TRP B 1 265 ? 107.782 60.839  188.576 1.00 77.45  ? 262 TRP B CD2 1 
ATOM   4740 N NE1 . TRP B 1 265 ? 105.643 61.485  188.399 1.00 79.67  ? 262 TRP B NE1 1 
ATOM   4741 C CE2 . TRP B 1 265 ? 106.554 60.577  187.929 1.00 82.80  ? 262 TRP B CE2 1 
ATOM   4742 C CE3 . TRP B 1 265 ? 108.889 60.042  188.267 1.00 81.64  ? 262 TRP B CE3 1 
ATOM   4743 C CZ2 . TRP B 1 265 ? 106.401 59.541  186.994 1.00 83.68  ? 262 TRP B CZ2 1 
ATOM   4744 C CZ3 . TRP B 1 265 ? 108.735 59.009  187.330 1.00 82.85  ? 262 TRP B CZ3 1 
ATOM   4745 C CH2 . TRP B 1 265 ? 107.500 58.770  186.712 1.00 82.00  ? 262 TRP B CH2 1 
ATOM   4746 N N   . ALA B 1 266 ? 107.233 65.340  191.028 1.00 61.80  ? 263 ALA B N   1 
ATOM   4747 C CA  . ALA B 1 266 ? 106.025 66.148  190.966 1.00 62.11  ? 263 ALA B CA  1 
ATOM   4748 C C   . ALA B 1 266 ? 106.291 67.539  190.393 1.00 60.46  ? 263 ALA B C   1 
ATOM   4749 O O   . ALA B 1 266 ? 105.363 68.181  189.903 1.00 64.62  ? 263 ALA B O   1 
ATOM   4750 C CB  . ALA B 1 266 ? 105.384 66.223  192.350 1.00 54.29  ? 263 ALA B CB  1 
ATOM   4751 N N   . THR B 1 267 ? 107.526 68.018  190.414 1.00 56.34  ? 264 THR B N   1 
ATOM   4752 C CA  . THR B 1 267 ? 107.807 69.312  189.816 1.00 60.50  ? 264 THR B CA  1 
ATOM   4753 C C   . THR B 1 267 ? 108.310 69.186  188.391 1.00 68.83  ? 264 THR B C   1 
ATOM   4754 O O   . THR B 1 267 ? 107.834 69.903  187.504 1.00 72.32  ? 264 THR B O   1 
ATOM   4755 C CB  . THR B 1 267 ? 108.845 70.078  190.652 1.00 62.81  ? 264 THR B CB  1 
ATOM   4756 O OG1 . THR B 1 267 ? 108.518 69.985  192.047 1.00 70.11  ? 264 THR B OG1 1 
ATOM   4757 C CG2 . THR B 1 267 ? 108.906 71.529  190.256 1.00 57.93  ? 264 THR B CG2 1 
ATOM   4758 N N   . GLN B 1 268 ? 109.244 68.265  188.145 1.00 70.24  ? 265 GLN B N   1 
ATOM   4759 C CA  . GLN B 1 268 ? 109.700 68.013  186.782 1.00 69.02  ? 265 GLN B CA  1 
ATOM   4760 C C   . GLN B 1 268 ? 108.549 67.522  185.926 1.00 67.11  ? 265 GLN B C   1 
ATOM   4761 O O   . GLN B 1 268 ? 108.162 68.170  184.951 1.00 73.13  ? 265 GLN B O   1 
ATOM   4762 C CB  . GLN B 1 268 ? 110.826 66.981  186.781 1.00 72.20  ? 265 GLN B CB  1 
ATOM   4763 C CG  . GLN B 1 268 ? 112.183 67.545  187.150 1.00 80.33  ? 265 GLN B CG  1 
ATOM   4764 C CD  . GLN B 1 268 ? 112.725 68.443  186.075 1.00 86.65  ? 265 GLN B CD  1 
ATOM   4765 O OE1 . GLN B 1 268 ? 112.215 68.446  184.946 1.00 78.53  ? 265 GLN B OE1 1 
ATOM   4766 N NE2 . GLN B 1 268 ? 113.760 69.223  186.411 1.00 92.22  ? 265 GLN B NE2 1 
ATOM   4767 N N   . VAL B 1 269 ? 107.970 66.388  186.310 1.00 63.44  ? 266 VAL B N   1 
ATOM   4768 C CA  . VAL B 1 269 ? 106.964 65.721  185.496 1.00 67.66  ? 266 VAL B CA  1 
ATOM   4769 C C   . VAL B 1 269 ? 105.593 66.371  185.654 1.00 71.11  ? 266 VAL B C   1 
ATOM   4770 O O   . VAL B 1 269 ? 104.934 66.713  184.669 1.00 68.61  ? 266 VAL B O   1 
ATOM   4771 C CB  . VAL B 1 269 ? 106.925 64.227  185.854 1.00 67.27  ? 266 VAL B CB  1 
ATOM   4772 C CG1 . VAL B 1 269 ? 105.829 63.529  185.100 1.00 66.37  ? 266 VAL B CG1 1 
ATOM   4773 C CG2 . VAL B 1 269 ? 108.272 63.597  185.548 1.00 66.74  ? 266 VAL B CG2 1 
ATOM   4774 N N   . GLN B 1 270 ? 105.131 66.564  186.882 1.00 75.29  ? 267 GLN B N   1 
ATOM   4775 C CA  . GLN B 1 270 ? 103.745 66.961  187.082 1.00 74.94  ? 267 GLN B CA  1 
ATOM   4776 C C   . GLN B 1 270 ? 103.591 68.436  187.421 1.00 67.73  ? 267 GLN B C   1 
ATOM   4777 O O   . GLN B 1 270 ? 102.477 68.886  187.707 1.00 62.84  ? 267 GLN B O   1 
ATOM   4778 C CB  . GLN B 1 270 ? 103.113 66.066  188.139 1.00 66.10  ? 267 GLN B CB  1 
ATOM   4779 C CG  . GLN B 1 270 ? 103.076 64.636  187.628 1.00 77.31  ? 267 GLN B CG  1 
ATOM   4780 C CD  . GLN B 1 270 ? 102.829 63.609  188.715 1.00 89.70  ? 267 GLN B CD  1 
ATOM   4781 O OE1 . GLN B 1 270 ? 103.035 63.872  189.904 1.00 83.73  ? 267 GLN B OE1 1 
ATOM   4782 N NE2 . GLN B 1 270 ? 102.393 62.417  188.309 1.00 95.99  ? 267 GLN B NE2 1 
ATOM   4783 N N   . ARG B 1 271 ? 104.688 69.194  187.377 1.00 69.46  ? 268 ARG B N   1 
ATOM   4784 C CA  . ARG B 1 271 ? 104.648 70.654  187.356 1.00 72.23  ? 268 ARG B CA  1 
ATOM   4785 C C   . ARG B 1 271 ? 104.063 71.237  188.644 1.00 73.29  ? 268 ARG B C   1 
ATOM   4786 O O   . ARG B 1 271 ? 103.344 72.241  188.621 1.00 73.77  ? 268 ARG B O   1 
ATOM   4787 C CB  . ARG B 1 271 ? 103.875 71.128  186.129 1.00 69.05  ? 268 ARG B CB  1 
ATOM   4788 C CG  . ARG B 1 271 ? 104.357 70.454  184.866 1.00 73.72  ? 268 ARG B CG  1 
ATOM   4789 C CD  . ARG B 1 271 ? 103.505 70.824  183.670 1.00 82.22  ? 268 ARG B CD  1 
ATOM   4790 N NE  . ARG B 1 271 ? 103.842 72.113  183.079 1.00 85.67  ? 268 ARG B NE  1 
ATOM   4791 C CZ  . ARG B 1 271 ? 103.156 72.666  182.089 1.00 89.98  ? 268 ARG B CZ  1 
ATOM   4792 N NH1 . ARG B 1 271 ? 102.096 72.064  181.567 1.00 92.61  ? 268 ARG B NH1 1 
ATOM   4793 N NH2 . ARG B 1 271 ? 103.538 73.851  181.615 1.00 90.38  ? 268 ARG B NH2 1 
ATOM   4794 N N   . ASP B 1 272 ? 104.400 70.620  189.786 1.00 68.71  ? 269 ASP B N   1 
ATOM   4795 C CA  . ASP B 1 272 ? 104.003 71.146  191.096 1.00 66.42  ? 269 ASP B CA  1 
ATOM   4796 C C   . ASP B 1 272 ? 105.088 72.123  191.533 1.00 67.96  ? 269 ASP B C   1 
ATOM   4797 O O   . ASP B 1 272 ? 106.014 71.796  192.275 1.00 67.07  ? 269 ASP B O   1 
ATOM   4798 C CB  . ASP B 1 272 ? 103.769 70.023  192.109 1.00 60.87  ? 269 ASP B CB  1 
ATOM   4799 C CG  . ASP B 1 272 ? 103.060 70.505  193.400 1.00 61.58  ? 269 ASP B CG  1 
ATOM   4800 O OD1 . ASP B 1 272 ? 103.005 71.729  193.679 1.00 58.36  ? 269 ASP B OD1 1 
ATOM   4801 O OD2 . ASP B 1 272 ? 102.530 69.641  194.135 1.00 58.71  ? 269 ASP B OD2 1 
ATOM   4802 N N   . TYR B 1 273 ? 104.987 73.338  191.010 1.00 70.53  ? 270 TYR B N   1 
ATOM   4803 C CA  . TYR B 1 273 ? 105.956 74.394  191.250 1.00 66.04  ? 270 TYR B CA  1 
ATOM   4804 C C   . TYR B 1 273 ? 105.654 75.230  192.494 1.00 63.17  ? 270 TYR B C   1 
ATOM   4805 O O   . TYR B 1 273 ? 106.506 76.022  192.908 1.00 61.63  ? 270 TYR B O   1 
ATOM   4806 C CB  . TYR B 1 273 ? 106.028 75.293  190.016 1.00 67.88  ? 270 TYR B CB  1 
ATOM   4807 C CG  . TYR B 1 273 ? 106.604 74.608  188.800 1.00 69.91  ? 270 TYR B CG  1 
ATOM   4808 C CD1 . TYR B 1 273 ? 107.977 74.387  188.680 1.00 71.34  ? 270 TYR B CD1 1 
ATOM   4809 C CD2 . TYR B 1 273 ? 105.779 74.144  187.795 1.00 74.69  ? 270 TYR B CD2 1 
ATOM   4810 C CE1 . TYR B 1 273 ? 108.508 73.756  187.567 1.00 70.13  ? 270 TYR B CE1 1 
ATOM   4811 C CE2 . TYR B 1 273 ? 106.296 73.516  186.673 1.00 77.18  ? 270 TYR B CE2 1 
ATOM   4812 C CZ  . TYR B 1 273 ? 107.654 73.316  186.567 1.00 78.69  ? 270 TYR B CZ  1 
ATOM   4813 O OH  . TYR B 1 273 ? 108.136 72.672  185.450 1.00 82.04  ? 270 TYR B OH  1 
ATOM   4814 N N   . HIS B 1 274 ? 104.485 75.069  193.111 1.00 60.74  ? 271 HIS B N   1 
ATOM   4815 C CA  . HIS B 1 274 ? 104.066 75.912  194.223 1.00 63.27  ? 271 HIS B CA  1 
ATOM   4816 C C   . HIS B 1 274 ? 103.541 75.036  195.339 1.00 65.87  ? 271 HIS B C   1 
ATOM   4817 O O   . HIS B 1 274 ? 102.830 74.050  195.093 1.00 65.89  ? 271 HIS B O   1 
ATOM   4818 C CB  . HIS B 1 274 ? 102.936 76.910  193.851 1.00 66.74  ? 271 HIS B CB  1 
ATOM   4819 C CG  . HIS B 1 274 ? 103.406 78.213  193.274 1.00 72.28  ? 271 HIS B CG  1 
ATOM   4820 N ND1 . HIS B 1 274 ? 104.281 78.297  192.205 1.00 69.35  ? 271 HIS B ND1 1 
ATOM   4821 C CD2 . HIS B 1 274 ? 103.079 79.489  193.593 1.00 69.45  ? 271 HIS B CD2 1 
ATOM   4822 C CE1 . HIS B 1 274 ? 104.486 79.567  191.905 1.00 67.25  ? 271 HIS B CE1 1 
ATOM   4823 N NE2 . HIS B 1 274 ? 103.770 80.310  192.734 1.00 76.72  ? 271 HIS B NE2 1 
ATOM   4824 N N   . GLY B 1 275 ? 103.892 75.411  196.565 1.00 58.19  ? 272 GLY B N   1 
ATOM   4825 C CA  . GLY B 1 275 ? 103.441 74.696  197.726 1.00 57.70  ? 272 GLY B CA  1 
ATOM   4826 C C   . GLY B 1 275 ? 103.657 75.477  199.002 1.00 62.15  ? 272 GLY B C   1 
ATOM   4827 O O   . GLY B 1 275 ? 104.174 76.605  199.003 1.00 60.96  ? 272 GLY B O   1 
ATOM   4828 N N   . PRO B 1 276 ? 103.262 74.871  200.122 1.00 56.83  ? 273 PRO B N   1 
ATOM   4829 C CA  . PRO B 1 276 ? 103.514 75.475  201.429 1.00 51.84  ? 273 PRO B CA  1 
ATOM   4830 C C   . PRO B 1 276 ? 104.993 75.697  201.661 1.00 53.68  ? 273 PRO B C   1 
ATOM   4831 O O   . PRO B 1 276 ? 105.837 74.929  201.199 1.00 57.13  ? 273 PRO B O   1 
ATOM   4832 C CB  . PRO B 1 276 ? 102.964 74.437  202.399 1.00 49.88  ? 273 PRO B CB  1 
ATOM   4833 C CG  . PRO B 1 276 ? 102.936 73.173  201.596 1.00 50.44  ? 273 PRO B CG  1 
ATOM   4834 C CD  . PRO B 1 276 ? 102.558 73.590  200.246 1.00 50.24  ? 273 PRO B CD  1 
ATOM   4835 N N   . ARG B 1 277 ? 105.304 76.775  202.363 1.00 54.97  ? 274 ARG B N   1 
ATOM   4836 C CA  . ARG B 1 277 ? 106.690 77.048  202.702 1.00 58.50  ? 274 ARG B CA  1 
ATOM   4837 C C   . ARG B 1 277 ? 107.226 75.959  203.629 1.00 53.28  ? 274 ARG B C   1 
ATOM   4838 O O   . ARG B 1 277 ? 106.702 75.754  204.723 1.00 51.62  ? 274 ARG B O   1 
ATOM   4839 C CB  . ARG B 1 277 ? 106.773 78.419  203.362 1.00 55.79  ? 274 ARG B CB  1 
ATOM   4840 C CG  . ARG B 1 277 ? 106.163 79.525  202.517 1.00 56.61  ? 274 ARG B CG  1 
ATOM   4841 C CD  . ARG B 1 277 ? 106.879 79.718  201.207 1.00 57.06  ? 274 ARG B CD  1 
ATOM   4842 N NE  . ARG B 1 277 ? 106.738 81.089  200.726 1.00 62.23  ? 274 ARG B NE  1 
ATOM   4843 C CZ  . ARG B 1 277 ? 107.413 81.603  199.706 1.00 63.72  ? 274 ARG B CZ  1 
ATOM   4844 N NH1 . ARG B 1 277 ? 108.303 80.891  199.031 1.00 60.68  ? 274 ARG B NH1 1 
ATOM   4845 N NH2 . ARG B 1 277 ? 107.205 82.870  199.367 1.00 65.71  ? 274 ARG B NH2 1 
ATOM   4846 N N   . LEU B 1 278 ? 108.274 75.256  203.198 1.00 51.61  ? 275 LEU B N   1 
ATOM   4847 C CA  . LEU B 1 278 ? 108.813 74.166  204.003 1.00 50.40  ? 275 LEU B CA  1 
ATOM   4848 C C   . LEU B 1 278 ? 109.968 74.572  204.900 1.00 53.99  ? 275 LEU B C   1 
ATOM   4849 O O   . LEU B 1 278 ? 110.281 73.847  205.850 1.00 54.25  ? 275 LEU B O   1 
ATOM   4850 C CB  . LEU B 1 278 ? 109.266 73.012  203.119 1.00 43.56  ? 275 LEU B CB  1 
ATOM   4851 C CG  . LEU B 1 278 ? 108.108 72.373  202.381 1.00 45.44  ? 275 LEU B CG  1 
ATOM   4852 C CD1 . LEU B 1 278 ? 108.536 71.014  201.857 1.00 43.28  ? 275 LEU B CD1 1 
ATOM   4853 C CD2 . LEU B 1 278 ? 106.906 72.261  203.322 1.00 47.69  ? 275 LEU B CD2 1 
ATOM   4854 N N   . LEU B 1 279 ? 110.641 75.679  204.617 1.00 55.45  ? 276 LEU B N   1 
ATOM   4855 C CA  . LEU B 1 279 ? 111.762 76.042  205.464 1.00 51.06  ? 276 LEU B CA  1 
ATOM   4856 C C   . LEU B 1 279 ? 111.337 76.341  206.892 1.00 53.10  ? 276 LEU B C   1 
ATOM   4857 O O   . LEU B 1 279 ? 112.159 76.109  207.793 1.00 59.36  ? 276 LEU B O   1 
ATOM   4858 C CB  . LEU B 1 279 ? 112.542 77.217  204.875 1.00 50.86  ? 276 LEU B CB  1 
ATOM   4859 C CG  . LEU B 1 279 ? 113.490 76.722  203.785 1.00 52.71  ? 276 LEU B CG  1 
ATOM   4860 C CD1 . LEU B 1 279 ? 114.501 77.790  203.417 1.00 58.46  ? 276 LEU B CD1 1 
ATOM   4861 C CD2 . LEU B 1 279 ? 114.163 75.400  204.122 1.00 52.39  ? 276 LEU B CD2 1 
ATOM   4862 N N   . PRO B 1 280 ? 110.143 76.877  207.175 1.00 52.82  ? 277 PRO B N   1 
ATOM   4863 C CA  . PRO B 1 280 ? 109.770 77.058  208.586 1.00 52.01  ? 277 PRO B CA  1 
ATOM   4864 C C   . PRO B 1 280 ? 109.835 75.792  209.399 1.00 51.15  ? 277 PRO B C   1 
ATOM   4865 O O   . PRO B 1 280 ? 110.275 75.839  210.555 1.00 56.67  ? 277 PRO B O   1 
ATOM   4866 C CB  . PRO B 1 280 ? 108.344 77.595  208.499 1.00 48.17  ? 277 PRO B CB  1 
ATOM   4867 C CG  . PRO B 1 280 ? 108.366 78.385  207.269 1.00 53.62  ? 277 PRO B CG  1 
ATOM   4868 C CD  . PRO B 1 280 ? 109.217 77.608  206.294 1.00 50.97  ? 277 PRO B CD  1 
ATOM   4869 N N   . TYR B 1 281 ? 109.512 74.647  208.809 1.00 50.21  ? 278 TYR B N   1 
ATOM   4870 C CA  . TYR B 1 281 ? 109.503 73.401  209.565 1.00 53.61  ? 278 TYR B CA  1 
ATOM   4871 C C   . TYR B 1 281 ? 110.887 72.890  209.947 1.00 52.16  ? 278 TYR B C   1 
ATOM   4872 O O   . TYR B 1 281 ? 110.978 72.026  210.824 1.00 51.30  ? 278 TYR B O   1 
ATOM   4873 C CB  . TYR B 1 281 ? 108.759 72.343  208.769 1.00 56.20  ? 278 TYR B CB  1 
ATOM   4874 C CG  . TYR B 1 281 ? 107.302 72.668  208.630 1.00 57.69  ? 278 TYR B CG  1 
ATOM   4875 C CD1 . TYR B 1 281 ? 106.414 72.339  209.636 1.00 59.75  ? 278 TYR B CD1 1 
ATOM   4876 C CD2 . TYR B 1 281 ? 106.823 73.358  207.530 1.00 56.33  ? 278 TYR B CD2 1 
ATOM   4877 C CE1 . TYR B 1 281 ? 105.089 72.640  209.533 1.00 56.48  ? 278 TYR B CE1 1 
ATOM   4878 C CE2 . TYR B 1 281 ? 105.496 73.670  207.424 1.00 57.21  ? 278 TYR B CE2 1 
ATOM   4879 C CZ  . TYR B 1 281 ? 104.638 73.304  208.434 1.00 59.40  ? 278 TYR B CZ  1 
ATOM   4880 O OH  . TYR B 1 281 ? 103.309 73.603  208.353 1.00 77.39  ? 278 TYR B OH  1 
ATOM   4881 N N   . ILE B 1 282 ? 111.962 73.410  209.347 1.00 52.83  ? 279 ILE B N   1 
ATOM   4882 C CA  . ILE B 1 282 ? 113.281 72.842  209.588 1.00 53.08  ? 279 ILE B CA  1 
ATOM   4883 C C   . ILE B 1 282 ? 114.021 73.562  210.698 1.00 50.17  ? 279 ILE B C   1 
ATOM   4884 O O   . ILE B 1 282 ? 115.141 73.162  211.038 1.00 53.48  ? 279 ILE B O   1 
ATOM   4885 C CB  . ILE B 1 282 ? 114.175 72.812  208.316 1.00 50.48  ? 279 ILE B CB  1 
ATOM   4886 C CG1 . ILE B 1 282 ? 114.791 74.180  208.019 1.00 53.79  ? 279 ILE B CG1 1 
ATOM   4887 C CG2 . ILE B 1 282 ? 113.415 72.345  207.116 1.00 45.64  ? 279 ILE B CG2 1 
ATOM   4888 C CD1 . ILE B 1 282 ? 115.864 74.147  206.953 1.00 48.90  ? 279 ILE B CD1 1 
ATOM   4889 N N   . MET B 1 283 ? 113.434 74.581  211.311 1.00 47.76  ? 280 MET B N   1 
ATOM   4890 C CA  . MET B 1 283 ? 114.218 75.322  212.302 1.00 54.36  ? 280 MET B CA  1 
ATOM   4891 C C   . MET B 1 283 ? 114.339 74.573  213.627 1.00 54.41  ? 280 MET B C   1 
ATOM   4892 O O   . MET B 1 283 ? 115.426 74.118  213.982 1.00 54.40  ? 280 MET B O   1 
ATOM   4893 C CB  . MET B 1 283 ? 113.614 76.708  212.508 1.00 51.97  ? 280 MET B CB  1 
ATOM   4894 C CG  . MET B 1 283 ? 113.852 77.598  211.330 1.00 57.94  ? 280 MET B CG  1 
ATOM   4895 S SD  . MET B 1 283 ? 113.017 79.139  211.606 1.00 60.51  ? 280 MET B SD  1 
ATOM   4896 C CE  . MET B 1 283 ? 113.166 79.211  213.400 1.00 60.22  ? 280 MET B CE  1 
ATOM   4897 N N   . PHE B 1 284 ? 113.225 74.363  214.334 1.00 57.55  ? 281 PHE B N   1 
ATOM   4898 C CA  . PHE B 1 284 ? 113.299 73.647  215.607 1.00 51.35  ? 281 PHE B CA  1 
ATOM   4899 C C   . PHE B 1 284 ? 113.908 72.261  215.494 1.00 54.58  ? 281 PHE B C   1 
ATOM   4900 O O   . PHE B 1 284 ? 114.707 71.906  216.377 1.00 56.82  ? 281 PHE B O   1 
ATOM   4901 C CB  . PHE B 1 284 ? 111.924 73.517  216.272 1.00 58.27  ? 281 PHE B CB  1 
ATOM   4902 C CG  . PHE B 1 284 ? 111.920 72.529  217.402 1.00 62.06  ? 281 PHE B CG  1 
ATOM   4903 C CD1 . PHE B 1 284 ? 112.499 72.836  218.616 1.00 66.28  ? 281 PHE B CD1 1 
ATOM   4904 C CD2 . PHE B 1 284 ? 111.432 71.248  217.213 1.00 65.53  ? 281 PHE B CD2 1 
ATOM   4905 C CE1 . PHE B 1 284 ? 112.542 71.900  219.632 1.00 67.55  ? 281 PHE B CE1 1 
ATOM   4906 C CE2 . PHE B 1 284 ? 111.476 70.314  218.226 1.00 64.40  ? 281 PHE B CE2 1 
ATOM   4907 C CZ  . PHE B 1 284 ? 112.038 70.634  219.424 1.00 62.09  ? 281 PHE B CZ  1 
ATOM   4908 N N   . PRO B 1 285 ? 113.578 71.424  214.502 1.00 57.57  ? 282 PRO B N   1 
ATOM   4909 C CA  . PRO B 1 285 ? 114.199 70.085  214.455 1.00 53.99  ? 282 PRO B CA  1 
ATOM   4910 C C   . PRO B 1 285 ? 115.690 70.123  214.142 1.00 53.31  ? 282 PRO B C   1 
ATOM   4911 O O   . PRO B 1 285 ? 116.351 69.075  214.209 1.00 45.85  ? 282 PRO B O   1 
ATOM   4912 C CB  . PRO B 1 285 ? 113.408 69.364  213.354 1.00 51.71  ? 282 PRO B CB  1 
ATOM   4913 C CG  . PRO B 1 285 ? 112.144 70.168  213.171 1.00 57.00  ? 282 PRO B CG  1 
ATOM   4914 C CD  . PRO B 1 285 ? 112.536 71.573  213.462 1.00 57.97  ? 282 PRO B CD  1 
ATOM   4915 N N   . ARG B 1 286 ? 116.235 71.309  213.847 1.00 55.97  ? 283 ARG B N   1 
ATOM   4916 C CA  . ARG B 1 286 ? 117.629 71.500  213.442 1.00 52.32  ? 283 ARG B CA  1 
ATOM   4917 C C   . ARG B 1 286 ? 117.972 70.528  212.322 1.00 48.43  ? 283 ARG B C   1 
ATOM   4918 O O   . ARG B 1 286 ? 119.013 69.870  212.309 1.00 51.02  ? 283 ARG B O   1 
ATOM   4919 C CB  . ARG B 1 286 ? 118.545 71.384  214.669 1.00 49.05  ? 283 ARG B CB  1 
ATOM   4920 C CG  . ARG B 1 286 ? 118.166 72.516  215.680 1.00 49.05  ? 283 ARG B CG  1 
ATOM   4921 C CD  . ARG B 1 286 ? 118.757 72.463  217.065 1.00 48.98  ? 283 ARG B CD  1 
ATOM   4922 N NE  . ARG B 1 286 ? 118.395 71.282  217.841 1.00 52.86  ? 283 ARG B NE  1 
ATOM   4923 C CZ  . ARG B 1 286 ? 117.270 71.127  218.525 1.00 53.34  ? 283 ARG B CZ  1 
ATOM   4924 N NH1 . ARG B 1 286 ? 116.306 72.027  218.497 1.00 53.70  ? 283 ARG B NH1 1 
ATOM   4925 N NH2 . ARG B 1 286 ? 117.114 70.042  219.267 1.00 56.97  ? 283 ARG B NH2 1 
ATOM   4926 N N   . ALA B 1 287 ? 117.056 70.473  211.355 1.00 48.96  ? 284 ALA B N   1 
ATOM   4927 C CA  . ALA B 1 287 ? 117.161 69.568  210.223 1.00 50.01  ? 284 ALA B CA  1 
ATOM   4928 C C   . ALA B 1 287 ? 118.209 70.055  209.232 1.00 53.63  ? 284 ALA B C   1 
ATOM   4929 O O   . ALA B 1 287 ? 118.395 71.260  209.022 1.00 50.77  ? 284 ALA B O   1 
ATOM   4930 C CB  . ALA B 1 287 ? 115.804 69.429  209.533 1.00 43.55  ? 284 ALA B CB  1 
ATOM   4931 N N   . THR B 1 288 ? 118.913 69.106  208.642 1.00 53.19  ? 285 THR B N   1 
ATOM   4932 C CA  . THR B 1 288 ? 119.901 69.381  207.609 1.00 52.76  ? 285 THR B CA  1 
ATOM   4933 C C   . THR B 1 288 ? 119.369 68.780  206.316 1.00 51.78  ? 285 THR B C   1 
ATOM   4934 O O   . THR B 1 288 ? 119.369 67.556  206.159 1.00 53.56  ? 285 THR B O   1 
ATOM   4935 C CB  . THR B 1 288 ? 121.269 68.788  207.978 1.00 51.71  ? 285 THR B CB  1 
ATOM   4936 O OG1 . THR B 1 288 ? 121.861 69.498  209.080 1.00 51.72  ? 285 THR B OG1 1 
ATOM   4937 C CG2 . THR B 1 288 ? 122.198 68.820  206.792 1.00 52.68  ? 285 THR B CG2 1 
ATOM   4938 N N   . ILE B 1 289 ? 118.902 69.631  205.396 1.00 49.52  ? 286 ILE B N   1 
ATOM   4939 C CA  . ILE B 1 289 ? 118.548 69.174  204.058 1.00 48.63  ? 286 ILE B CA  1 
ATOM   4940 C C   . ILE B 1 289 ? 119.752 69.311  203.142 1.00 47.89  ? 286 ILE B C   1 
ATOM   4941 O O   . ILE B 1 289 ? 120.519 70.269  203.248 1.00 50.53  ? 286 ILE B O   1 
ATOM   4942 C CB  . ILE B 1 289 ? 117.353 69.953  203.501 1.00 51.62  ? 286 ILE B CB  1 
ATOM   4943 C CG1 . ILE B 1 289 ? 116.278 70.078  204.555 1.00 50.89  ? 286 ILE B CG1 1 
ATOM   4944 C CG2 . ILE B 1 289 ? 116.822 69.265  202.247 1.00 54.60  ? 286 ILE B CG2 1 
ATOM   4945 C CD1 . ILE B 1 289 ? 115.243 71.054  204.150 1.00 53.16  ? 286 ILE B CD1 1 
ATOM   4946 N N   . ARG B 1 290 ? 119.927 68.350  202.243 1.00 44.61  ? 287 ARG B N   1 
ATOM   4947 C CA  . ARG B 1 290 ? 121.038 68.412  201.304 1.00 51.79  ? 287 ARG B CA  1 
ATOM   4948 C C   . ARG B 1 290 ? 120.618 67.962  199.912 1.00 52.83  ? 287 ARG B C   1 
ATOM   4949 O O   . ARG B 1 290 ? 119.930 66.946  199.765 1.00 56.32  ? 287 ARG B O   1 
ATOM   4950 C CB  . ARG B 1 290 ? 122.207 67.558  201.777 1.00 51.87  ? 287 ARG B CB  1 
ATOM   4951 C CG  . ARG B 1 290 ? 123.420 67.752  200.902 1.00 52.42  ? 287 ARG B CG  1 
ATOM   4952 C CD  . ARG B 1 290 ? 124.451 66.737  201.229 1.00 53.70  ? 287 ARG B CD  1 
ATOM   4953 N NE  . ARG B 1 290 ? 125.718 67.041  200.587 1.00 53.61  ? 287 ARG B NE  1 
ATOM   4954 C CZ  . ARG B 1 290 ? 126.013 66.690  199.349 1.00 49.77  ? 287 ARG B CZ  1 
ATOM   4955 N NH1 . ARG B 1 290 ? 125.132 66.071  198.584 1.00 49.23  ? 287 ARG B NH1 1 
ATOM   4956 N NH2 . ARG B 1 290 ? 127.221 66.968  198.868 1.00 57.11  ? 287 ARG B NH2 1 
ATOM   4957 N N   . GLY B 1 291 ? 121.030 68.714  198.894 1.00 46.14  ? 288 GLY B N   1 
ATOM   4958 C CA  . GLY B 1 291 ? 120.774 68.301  197.525 1.00 51.16  ? 288 GLY B CA  1 
ATOM   4959 C C   . GLY B 1 291 ? 121.712 67.203  197.037 1.00 53.05  ? 288 GLY B C   1 
ATOM   4960 O O   . GLY B 1 291 ? 122.895 67.144  197.371 1.00 55.90  ? 288 GLY B O   1 
ATOM   4961 N N   . ILE B 1 292 ? 121.176 66.333  196.190 1.00 47.97  ? 289 ILE B N   1 
ATOM   4962 C CA  . ILE B 1 292 ? 121.904 65.192  195.659 1.00 47.46  ? 289 ILE B CA  1 
ATOM   4963 C C   . ILE B 1 292 ? 122.146 65.402  194.164 1.00 52.15  ? 289 ILE B C   1 
ATOM   4964 O O   . ILE B 1 292 ? 121.222 65.718  193.404 1.00 53.61  ? 289 ILE B O   1 
ATOM   4965 C CB  . ILE B 1 292 ? 121.143 63.881  195.930 1.00 52.12  ? 289 ILE B CB  1 
ATOM   4966 C CG1 . ILE B 1 292 ? 121.037 63.592  197.417 1.00 48.90  ? 289 ILE B CG1 1 
ATOM   4967 C CG2 . ILE B 1 292 ? 121.887 62.711  195.343 1.00 55.91  ? 289 ILE B CG2 1 
ATOM   4968 C CD1 . ILE B 1 292 ? 122.385 63.304  198.025 1.00 45.30  ? 289 ILE B CD1 1 
ATOM   4969 N N   . PHE B 1 293 ? 123.408 65.281  193.759 1.00 51.67  ? 290 PHE B N   1 
ATOM   4970 C CA  . PHE B 1 293 ? 123.815 65.279  192.358 1.00 49.13  ? 290 PHE B CA  1 
ATOM   4971 C C   . PHE B 1 293 ? 124.997 64.315  192.252 1.00 49.91  ? 290 PHE B C   1 
ATOM   4972 O O   . PHE B 1 293 ? 126.158 64.725  192.354 1.00 47.04  ? 290 PHE B O   1 
ATOM   4973 C CB  . PHE B 1 293 ? 124.166 66.665  191.848 1.00 54.38  ? 290 PHE B CB  1 
ATOM   4974 C CG  . PHE B 1 293 ? 124.304 66.733  190.345 1.00 61.14  ? 290 PHE B CG  1 
ATOM   4975 C CD1 . PHE B 1 293 ? 123.191 66.585  189.525 1.00 55.37  ? 290 PHE B CD1 1 
ATOM   4976 C CD2 . PHE B 1 293 ? 125.543 66.951  189.753 1.00 61.71  ? 290 PHE B CD2 1 
ATOM   4977 C CE1 . PHE B 1 293 ? 123.310 66.652  188.170 1.00 57.85  ? 290 PHE B CE1 1 
ATOM   4978 C CE2 . PHE B 1 293 ? 125.666 67.014  188.386 1.00 57.87  ? 290 PHE B CE2 1 
ATOM   4979 C CZ  . PHE B 1 293 ? 124.548 66.872  187.597 1.00 59.50  ? 290 PHE B CZ  1 
ATOM   4980 N N   . SER B 1 294 ? 124.677 63.026  192.096 1.00 46.65  ? 291 SER B N   1 
ATOM   4981 C CA  . SER B 1 294 ? 125.652 61.974  192.338 1.00 48.09  ? 291 SER B CA  1 
ATOM   4982 C C   . SER B 1 294 ? 126.833 62.017  191.377 1.00 50.37  ? 291 SER B C   1 
ATOM   4983 O O   . SER B 1 294 ? 127.819 61.312  191.611 1.00 51.00  ? 291 SER B O   1 
ATOM   4984 C CB  . SER B 1 294 ? 124.964 60.606  192.316 1.00 47.75  ? 291 SER B CB  1 
ATOM   4985 O OG  . SER B 1 294 ? 124.204 60.436  191.143 1.00 53.31  ? 291 SER B OG  1 
ATOM   4986 N N   . LEU B 1 295 ? 126.769 62.810  190.306 1.00 54.38  ? 292 LEU B N   1 
ATOM   4987 C CA  . LEU B 1 295 ? 127.956 62.989  189.471 1.00 52.51  ? 292 LEU B CA  1 
ATOM   4988 C C   . LEU B 1 295 ? 129.171 63.364  190.302 1.00 50.12  ? 292 LEU B C   1 
ATOM   4989 O O   . LEU B 1 295 ? 130.285 62.932  190.000 1.00 53.40  ? 292 LEU B O   1 
ATOM   4990 C CB  . LEU B 1 295 ? 127.731 64.050  188.392 1.00 50.91  ? 292 LEU B CB  1 
ATOM   4991 C CG  . LEU B 1 295 ? 126.957 63.665  187.128 1.00 53.53  ? 292 LEU B CG  1 
ATOM   4992 C CD1 . LEU B 1 295 ? 127.321 64.588  185.992 1.00 55.83  ? 292 LEU B CD1 1 
ATOM   4993 C CD2 . LEU B 1 295 ? 127.255 62.255  186.703 1.00 53.66  ? 292 LEU B CD2 1 
ATOM   4994 N N   . GLU B 1 296 ? 128.981 64.148  191.367 1.00 49.55  ? 293 GLU B N   1 
ATOM   4995 C CA  . GLU B 1 296 ? 130.135 64.584  192.141 1.00 47.94  ? 293 GLU B CA  1 
ATOM   4996 C C   . GLU B 1 296 ? 130.936 63.390  192.648 1.00 50.94  ? 293 GLU B C   1 
ATOM   4997 O O   . GLU B 1 296 ? 132.134 63.521  192.894 1.00 53.34  ? 293 GLU B O   1 
ATOM   4998 C CB  . GLU B 1 296 ? 129.701 65.519  193.294 1.00 46.96  ? 293 GLU B CB  1 
ATOM   4999 C CG  . GLU B 1 296 ? 129.056 64.857  194.519 1.00 50.44  ? 293 GLU B CG  1 
ATOM   5000 C CD  . GLU B 1 296 ? 128.719 65.837  195.680 1.00 54.37  ? 293 GLU B CD  1 
ATOM   5001 O OE1 . GLU B 1 296 ? 129.455 66.821  195.939 1.00 54.05  ? 293 GLU B OE1 1 
ATOM   5002 O OE2 . GLU B 1 296 ? 127.706 65.595  196.366 1.00 52.17  ? 293 GLU B OE2 1 
ATOM   5003 N N   . TRP B 1 297 ? 130.312 62.220  192.763 1.00 55.07  ? 294 TRP B N   1 
ATOM   5004 C CA  . TRP B 1 297 ? 130.930 61.042  193.356 1.00 51.62  ? 294 TRP B CA  1 
ATOM   5005 C C   . TRP B 1 297 ? 131.526 60.079  192.344 1.00 52.25  ? 294 TRP B C   1 
ATOM   5006 O O   . TRP B 1 297 ? 132.050 59.034  192.748 1.00 54.09  ? 294 TRP B O   1 
ATOM   5007 C CB  . TRP B 1 297 ? 129.899 60.291  194.207 1.00 48.94  ? 294 TRP B CB  1 
ATOM   5008 C CG  . TRP B 1 297 ? 129.376 61.089  195.364 1.00 49.22  ? 294 TRP B CG  1 
ATOM   5009 C CD1 . TRP B 1 297 ? 130.070 61.985  196.113 1.00 47.17  ? 294 TRP B CD1 1 
ATOM   5010 C CD2 . TRP B 1 297 ? 128.047 61.054  195.912 1.00 53.79  ? 294 TRP B CD2 1 
ATOM   5011 N NE1 . TRP B 1 297 ? 129.261 62.514  197.089 1.00 47.87  ? 294 TRP B NE1 1 
ATOM   5012 C CE2 . TRP B 1 297 ? 128.015 61.962  196.986 1.00 48.02  ? 294 TRP B CE2 1 
ATOM   5013 C CE3 . TRP B 1 297 ? 126.878 60.351  195.589 1.00 54.44  ? 294 TRP B CE3 1 
ATOM   5014 C CZ2 . TRP B 1 297 ? 126.864 62.188  197.737 1.00 47.51  ? 294 TRP B CZ2 1 
ATOM   5015 C CZ3 . TRP B 1 297 ? 125.731 60.575  196.350 1.00 50.42  ? 294 TRP B CZ3 1 
ATOM   5016 C CH2 . TRP B 1 297 ? 125.737 61.485  197.407 1.00 49.23  ? 294 TRP B CH2 1 
ATOM   5017 N N   . PHE B 1 298 ? 131.481 60.397  191.052 1.00 50.29  ? 295 PHE B N   1 
ATOM   5018 C CA  . PHE B 1 298 ? 131.974 59.480  190.019 1.00 51.22  ? 295 PHE B CA  1 
ATOM   5019 C C   . PHE B 1 298 ? 133.497 59.586  189.948 1.00 51.06  ? 295 PHE B C   1 
ATOM   5020 O O   . PHE B 1 298 ? 134.073 60.186  189.039 1.00 55.26  ? 295 PHE B O   1 
ATOM   5021 C CB  . PHE B 1 298 ? 131.333 59.789  188.668 1.00 51.85  ? 295 PHE B CB  1 
ATOM   5022 C CG  . PHE B 1 298 ? 129.907 59.320  188.537 1.00 53.86  ? 295 PHE B CG  1 
ATOM   5023 C CD1 . PHE B 1 298 ? 129.160 58.957  189.648 1.00 54.01  ? 295 PHE B CD1 1 
ATOM   5024 C CD2 . PHE B 1 298 ? 129.307 59.254  187.291 1.00 49.76  ? 295 PHE B CD2 1 
ATOM   5025 C CE1 . PHE B 1 298 ? 127.839 58.524  189.505 1.00 51.86  ? 295 PHE B CE1 1 
ATOM   5026 C CE2 . PHE B 1 298 ? 127.997 58.813  187.147 1.00 46.20  ? 295 PHE B CE2 1 
ATOM   5027 C CZ  . PHE B 1 298 ? 127.264 58.453  188.258 1.00 48.26  ? 295 PHE B CZ  1 
ATOM   5028 N N   . THR B 1 299 ? 134.160 58.969  190.927 1.00 51.06  ? 296 THR B N   1 
ATOM   5029 C CA  . THR B 1 299 ? 135.608 58.868  190.958 1.00 52.12  ? 296 THR B CA  1 
ATOM   5030 C C   . THR B 1 299 ? 135.995 57.410  191.160 1.00 54.83  ? 296 THR B C   1 
ATOM   5031 O O   . THR B 1 299 ? 135.203 56.603  191.648 1.00 55.09  ? 296 THR B O   1 
ATOM   5032 C CB  . THR B 1 299 ? 136.203 59.692  192.083 1.00 50.56  ? 296 THR B CB  1 
ATOM   5033 O OG1 . THR B 1 299 ? 135.986 59.003  193.313 1.00 53.03  ? 296 THR B OG1 1 
ATOM   5034 C CG2 . THR B 1 299 ? 135.504 61.016  192.149 1.00 43.66  ? 296 THR B CG2 1 
ATOM   5035 N N   . GLU B 1 300 ? 137.243 57.086  190.823 1.00 57.51  ? 297 GLU B N   1 
ATOM   5036 C CA  . GLU B 1 300 ? 137.646 55.683  190.785 1.00 62.31  ? 297 GLU B CA  1 
ATOM   5037 C C   . GLU B 1 300 ? 137.554 55.037  192.156 1.00 63.51  ? 297 GLU B C   1 
ATOM   5038 O O   . GLU B 1 300 ? 137.045 53.916  192.287 1.00 62.46  ? 297 GLU B O   1 
ATOM   5039 C CB  . GLU B 1 300 ? 139.050 55.535  190.216 1.00 67.03  ? 297 GLU B CB  1 
ATOM   5040 C CG  . GLU B 1 300 ? 139.178 56.138  188.841 1.00 80.53  ? 297 GLU B CG  1 
ATOM   5041 C CD  . GLU B 1 300 ? 140.552 55.922  188.265 1.00 93.76  ? 297 GLU B CD  1 
ATOM   5042 O OE1 . GLU B 1 300 ? 141.390 55.304  188.974 1.00 94.33  ? 297 GLU B OE1 1 
ATOM   5043 O OE2 . GLU B 1 300 ? 140.787 56.374  187.118 1.00 89.60  ? 297 GLU B OE2 1 
ATOM   5044 N N   . GLN B 1 301 ? 138.063 55.712  193.187 1.00 61.28  ? 298 GLN B N   1 
ATOM   5045 C CA  . GLN B 1 301 ? 137.968 55.139  194.523 1.00 61.13  ? 298 GLN B CA  1 
ATOM   5046 C C   . GLN B 1 301 ? 136.517 54.816  194.846 1.00 57.68  ? 298 GLN B C   1 
ATOM   5047 O O   . GLN B 1 301 ? 136.205 53.715  195.314 1.00 55.45  ? 298 GLN B O   1 
ATOM   5048 C CB  . GLN B 1 301 ? 138.561 56.096  195.564 1.00 61.81  ? 298 GLN B CB  1 
ATOM   5049 C CG  . GLN B 1 301 ? 139.968 56.631  195.248 1.00 70.48  ? 298 GLN B CG  1 
ATOM   5050 C CD  . GLN B 1 301 ? 139.965 57.858  194.303 1.00 85.68  ? 298 GLN B CD  1 
ATOM   5051 O OE1 . GLN B 1 301 ? 139.560 57.779  193.122 1.00 72.98  ? 298 GLN B OE1 1 
ATOM   5052 N NE2 . GLN B 1 301 ? 140.403 59.006  194.837 1.00 90.86  ? 298 GLN B NE2 1 
ATOM   5053 N N   . ASN B 1 302 ? 135.610 55.736  194.521 1.00 54.39  ? 299 ASN B N   1 
ATOM   5054 C CA  . ASN B 1 302 ? 134.195 55.510  194.782 1.00 51.44  ? 299 ASN B CA  1 
ATOM   5055 C C   . ASN B 1 302 ? 133.676 54.305  194.015 1.00 51.49  ? 299 ASN B C   1 
ATOM   5056 O O   . ASN B 1 302 ? 132.899 53.514  194.555 1.00 48.89  ? 299 ASN B O   1 
ATOM   5057 C CB  . ASN B 1 302 ? 133.398 56.756  194.410 1.00 54.56  ? 299 ASN B CB  1 
ATOM   5058 C CG  . ASN B 1 302 ? 133.536 57.869  195.434 1.00 54.55  ? 299 ASN B CG  1 
ATOM   5059 O OD1 . ASN B 1 302 ? 133.735 57.627  196.629 1.00 47.37  ? 299 ASN B OD1 1 
ATOM   5060 N ND2 . ASN B 1 302 ? 133.432 59.107  194.963 1.00 54.54  ? 299 ASN B ND2 1 
ATOM   5061 N N   . TRP B 1 303 ? 134.063 54.170  192.739 1.00 54.35  ? 300 TRP B N   1 
ATOM   5062 C CA  . TRP B 1 303 ? 133.627 53.019  191.952 1.00 49.55  ? 300 TRP B CA  1 
ATOM   5063 C C   . TRP B 1 303 ? 134.164 51.720  192.530 1.00 50.55  ? 300 TRP B C   1 
ATOM   5064 O O   . TRP B 1 303 ? 133.418 50.744  192.666 1.00 48.72  ? 300 TRP B O   1 
ATOM   5065 C CB  . TRP B 1 303 ? 134.046 53.178  190.490 1.00 50.40  ? 300 TRP B CB  1 
ATOM   5066 C CG  . TRP B 1 303 ? 133.244 54.213  189.747 1.00 50.03  ? 300 TRP B CG  1 
ATOM   5067 C CD1 . TRP B 1 303 ? 133.717 55.345  189.163 1.00 50.70  ? 300 TRP B CD1 1 
ATOM   5068 C CD2 . TRP B 1 303 ? 131.829 54.202  189.508 1.00 49.07  ? 300 TRP B CD2 1 
ATOM   5069 N NE1 . TRP B 1 303 ? 132.688 56.051  188.590 1.00 49.89  ? 300 TRP B NE1 1 
ATOM   5070 C CE2 . TRP B 1 303 ? 131.517 55.372  188.795 1.00 49.39  ? 300 TRP B CE2 1 
ATOM   5071 C CE3 . TRP B 1 303 ? 130.791 53.328  189.852 1.00 50.30  ? 300 TRP B CE3 1 
ATOM   5072 C CZ2 . TRP B 1 303 ? 130.207 55.688  188.407 1.00 52.30  ? 300 TRP B CZ2 1 
ATOM   5073 C CZ3 . TRP B 1 303 ? 129.485 53.644  189.458 1.00 48.04  ? 300 TRP B CZ3 1 
ATOM   5074 C CH2 . TRP B 1 303 ? 129.210 54.809  188.740 1.00 47.11  ? 300 TRP B CH2 1 
ATOM   5075 N N   . SER B 1 304 ? 135.446 51.697  192.914 1.00 56.32  ? 301 SER B N   1 
ATOM   5076 C CA  . SER B 1 304 ? 135.987 50.527  193.606 1.00 55.62  ? 301 SER B CA  1 
ATOM   5077 C C   . SER B 1 304 ? 135.123 50.186  194.799 1.00 49.95  ? 301 SER B C   1 
ATOM   5078 O O   . SER B 1 304 ? 134.697 49.042  194.970 1.00 47.49  ? 301 SER B O   1 
ATOM   5079 C CB  . SER B 1 304 ? 137.429 50.766  194.057 1.00 54.44  ? 301 SER B CB  1 
ATOM   5080 O OG  . SER B 1 304 ? 138.273 51.067  192.962 1.00 63.55  ? 301 SER B OG  1 
ATOM   5081 N N   . ALA B 1 305 ? 134.876 51.192  195.642 1.00 55.91  ? 302 ALA B N   1 
ATOM   5082 C CA  . ALA B 1 305 ? 134.057 51.034  196.838 1.00 55.16  ? 302 ALA B CA  1 
ATOM   5083 C C   . ALA B 1 305 ? 132.642 50.562  196.511 1.00 55.62  ? 302 ALA B C   1 
ATOM   5084 O O   . ALA B 1 305 ? 132.080 49.731  197.239 1.00 54.83  ? 302 ALA B O   1 
ATOM   5085 C CB  . ALA B 1 305 ? 134.020 52.356  197.603 1.00 49.05  ? 302 ALA B CB  1 
ATOM   5086 N N   . LEU B 1 306 ? 132.008 51.083  195.487 1.00 52.08  ? 303 LEU B N   1 
ATOM   5087 C CA  . LEU B 1 306 ? 130.653 50.655  195.254 1.00 48.77  ? 303 LEU B CA  1 
ATOM   5088 C C   . LEU B 1 306 ? 130.640 49.186  194.941 1.00 50.40  ? 303 LEU B C   1 
ATOM   5089 O O   . LEU B 1 306 ? 129.748 48.471  195.358 1.00 52.08  ? 303 LEU B O   1 
ATOM   5090 C CB  . LEU B 1 306 ? 130.023 51.424  194.111 1.00 48.68  ? 303 LEU B CB  1 
ATOM   5091 C CG  . LEU B 1 306 ? 128.506 51.401  194.009 1.00 49.77  ? 303 LEU B CG  1 
ATOM   5092 C CD1 . LEU B 1 306 ? 127.950 52.536  194.839 1.00 47.80  ? 303 LEU B CD1 1 
ATOM   5093 C CD2 . LEU B 1 306 ? 128.091 51.555  192.559 1.00 49.46  ? 303 LEU B CD2 1 
ATOM   5094 N N   . HIS B 1 307 ? 131.635 48.716  194.217 1.00 51.81  ? 304 HIS B N   1 
ATOM   5095 C CA  . HIS B 1 307 ? 131.666 47.286  193.970 1.00 53.31  ? 304 HIS B CA  1 
ATOM   5096 C C   . HIS B 1 307 ? 131.936 46.510  195.252 1.00 51.85  ? 304 HIS B C   1 
ATOM   5097 O O   . HIS B 1 307 ? 131.315 45.469  195.495 1.00 53.60  ? 304 HIS B O   1 
ATOM   5098 C CB  . HIS B 1 307 ? 132.698 46.964  192.896 1.00 54.22  ? 304 HIS B CB  1 
ATOM   5099 C CG  . HIS B 1 307 ? 132.250 47.313  191.512 1.00 53.04  ? 304 HIS B CG  1 
ATOM   5100 N ND1 . HIS B 1 307 ? 132.389 48.579  190.984 1.00 54.24  ? 304 HIS B ND1 1 
ATOM   5101 C CD2 . HIS B 1 307 ? 131.653 46.567  190.550 1.00 59.04  ? 304 HIS B CD2 1 
ATOM   5102 C CE1 . HIS B 1 307 ? 131.915 48.596  189.749 1.00 63.67  ? 304 HIS B CE1 1 
ATOM   5103 N NE2 . HIS B 1 307 ? 131.453 47.390  189.464 1.00 67.46  ? 304 HIS B NE2 1 
ATOM   5104 N N   . GLU B 1 308 ? 132.886 46.971  196.058 1.00 53.52  ? 305 GLU B N   1 
ATOM   5105 C CA  . GLU B 1 308 ? 133.207 46.267  197.290 1.00 58.41  ? 305 GLU B CA  1 
ATOM   5106 C C   . GLU B 1 308 ? 132.000 46.279  198.224 1.00 58.80  ? 305 GLU B C   1 
ATOM   5107 O O   . GLU B 1 308 ? 131.388 45.228  198.445 1.00 57.59  ? 305 GLU B O   1 
ATOM   5108 C CB  . GLU B 1 308 ? 134.423 46.897  197.963 1.00 59.76  ? 305 GLU B CB  1 
ATOM   5109 C CG  . GLU B 1 308 ? 135.154 45.997  198.933 1.00 64.80  ? 305 GLU B CG  1 
ATOM   5110 C CD  . GLU B 1 308 ? 136.044 46.790  199.889 1.00 91.01  ? 305 GLU B CD  1 
ATOM   5111 O OE1 . GLU B 1 308 ? 135.849 48.027  200.009 1.00 91.02  ? 305 GLU B OE1 1 
ATOM   5112 O OE2 . GLU B 1 308 ? 136.944 46.180  200.518 1.00 100.65 ? 305 GLU B OE2 1 
ATOM   5113 N N   . GLU B 1 309 ? 131.614 47.455  198.731 1.00 56.40  ? 306 GLU B N   1 
ATOM   5114 C CA  . GLU B 1 309 ? 130.509 47.519  199.687 1.00 57.77  ? 306 GLU B CA  1 
ATOM   5115 C C   . GLU B 1 309 ? 129.217 46.947  199.097 1.00 59.95  ? 306 GLU B C   1 
ATOM   5116 O O   . GLU B 1 309 ? 128.730 45.902  199.540 1.00 61.34  ? 306 GLU B O   1 
ATOM   5117 C CB  . GLU B 1 309 ? 130.284 48.957  200.180 1.00 57.10  ? 306 GLU B CB  1 
ATOM   5118 C CG  . GLU B 1 309 ? 131.449 49.609  200.952 1.00 54.59  ? 306 GLU B CG  1 
ATOM   5119 C CD  . GLU B 1 309 ? 130.953 50.605  202.025 1.00 64.10  ? 306 GLU B CD  1 
ATOM   5120 O OE1 . GLU B 1 309 ? 129.806 50.438  202.506 1.00 62.94  ? 306 GLU B OE1 1 
ATOM   5121 O OE2 . GLU B 1 309 ? 131.702 51.546  202.398 1.00 67.97  ? 306 GLU B OE2 1 
ATOM   5122 N N   . LEU B 1 310 ? 128.689 47.582  198.046 1.00 61.48  ? 307 LEU B N   1 
ATOM   5123 C CA  . LEU B 1 310 ? 127.363 47.226  197.545 1.00 59.57  ? 307 LEU B CA  1 
ATOM   5124 C C   . LEU B 1 310 ? 127.384 45.899  196.804 1.00 60.05  ? 307 LEU B C   1 
ATOM   5125 O O   . LEU B 1 310 ? 126.498 45.058  196.994 1.00 58.53  ? 307 LEU B O   1 
ATOM   5126 C CB  . LEU B 1 310 ? 126.840 48.322  196.615 1.00 57.87  ? 307 LEU B CB  1 
ATOM   5127 C CG  . LEU B 1 310 ? 125.871 49.343  197.190 1.00 62.00  ? 307 LEU B CG  1 
ATOM   5128 C CD1 . LEU B 1 310 ? 125.399 50.309  196.107 1.00 58.39  ? 307 LEU B CD1 1 
ATOM   5129 C CD2 . LEU B 1 310 ? 124.729 48.591  197.789 1.00 63.84  ? 307 LEU B CD2 1 
ATOM   5130 N N   . GLY B 1 311 ? 128.368 45.719  195.919 1.00 60.45  ? 308 GLY B N   1 
ATOM   5131 C CA  . GLY B 1 311 ? 128.408 44.526  195.085 1.00 59.10  ? 308 GLY B CA  1 
ATOM   5132 C C   . GLY B 1 311 ? 128.446 43.244  195.886 1.00 62.96  ? 308 GLY B C   1 
ATOM   5133 O O   . GLY B 1 311 ? 127.799 42.259  195.523 1.00 65.39  ? 308 GLY B O   1 
ATOM   5134 N N   . GLY B 1 312 ? 129.223 43.232  196.972 1.00 63.81  ? 309 GLY B N   1 
ATOM   5135 C CA  . GLY B 1 312 ? 129.214 42.082  197.862 1.00 65.02  ? 309 GLY B CA  1 
ATOM   5136 C C   . GLY B 1 312 ? 127.822 41.749  198.372 1.00 70.22  ? 309 GLY B C   1 
ATOM   5137 O O   . GLY B 1 312 ? 127.338 40.630  198.189 1.00 67.09  ? 309 GLY B O   1 
ATOM   5138 N N   . LEU B 1 313 ? 127.142 42.736  198.983 1.00 68.61  ? 310 LEU B N   1 
ATOM   5139 C CA  . LEU B 1 313 ? 125.812 42.512  199.548 1.00 60.73  ? 310 LEU B CA  1 
ATOM   5140 C C   . LEU B 1 313 ? 124.858 41.936  198.522 1.00 61.02  ? 310 LEU B C   1 
ATOM   5141 O O   . LEU B 1 313 ? 124.055 41.063  198.846 1.00 67.32  ? 310 LEU B O   1 
ATOM   5142 C CB  . LEU B 1 313 ? 125.234 43.808  200.114 1.00 57.84  ? 310 LEU B CB  1 
ATOM   5143 C CG  . LEU B 1 313 ? 125.958 44.572  201.216 1.00 61.26  ? 310 LEU B CG  1 
ATOM   5144 C CD1 . LEU B 1 313 ? 125.275 45.914  201.387 1.00 57.18  ? 310 LEU B CD1 1 
ATOM   5145 C CD2 . LEU B 1 313 ? 125.955 43.787  202.522 1.00 59.65  ? 310 LEU B CD2 1 
ATOM   5146 N N   . VAL B 1 314 ? 124.918 42.416  197.283 1.00 61.70  ? 311 VAL B N   1 
ATOM   5147 C CA  . VAL B 1 314 ? 124.038 41.885  196.247 1.00 62.76  ? 311 VAL B CA  1 
ATOM   5148 C C   . VAL B 1 314 ? 124.355 40.422  195.996 1.00 64.71  ? 311 VAL B C   1 
ATOM   5149 O O   . VAL B 1 314 ? 123.467 39.558  195.985 1.00 64.49  ? 311 VAL B O   1 
ATOM   5150 C CB  . VAL B 1 314 ? 124.172 42.706  194.956 1.00 60.41  ? 311 VAL B CB  1 
ATOM   5151 C CG1 . VAL B 1 314 ? 123.351 42.075  193.857 1.00 58.49  ? 311 VAL B CG1 1 
ATOM   5152 C CG2 . VAL B 1 314 ? 123.743 44.140  195.203 1.00 63.09  ? 311 VAL B CG2 1 
ATOM   5153 N N   . ARG B 1 315 ? 125.641 40.121  195.834 1.00 68.37  ? 312 ARG B N   1 
ATOM   5154 C CA  . ARG B 1 315 ? 126.059 38.767  195.505 1.00 77.67  ? 312 ARG B CA  1 
ATOM   5155 C C   . ARG B 1 315 ? 125.754 37.794  196.636 1.00 82.54  ? 312 ARG B C   1 
ATOM   5156 O O   . ARG B 1 315 ? 125.533 36.605  196.365 1.00 83.69  ? 312 ARG B O   1 
ATOM   5157 C CB  . ARG B 1 315 ? 127.566 38.758  195.233 1.00 70.93  ? 312 ARG B CB  1 
ATOM   5158 C CG  . ARG B 1 315 ? 127.984 39.424  193.955 1.00 67.27  ? 312 ARG B CG  1 
ATOM   5159 C CD  . ARG B 1 315 ? 129.398 39.076  193.623 1.00 67.46  ? 312 ARG B CD  1 
ATOM   5160 N NE  . ARG B 1 315 ? 130.265 39.794  194.548 1.00 70.30  ? 312 ARG B NE  1 
ATOM   5161 C CZ  . ARG B 1 315 ? 130.973 40.868  194.226 1.00 73.10  ? 312 ARG B CZ  1 
ATOM   5162 N NH1 . ARG B 1 315 ? 130.908 41.398  193.010 1.00 68.78  ? 312 ARG B NH1 1 
ATOM   5163 N NH2 . ARG B 1 315 ? 131.751 41.432  195.151 1.00 60.21  ? 312 ARG B NH2 1 
ATOM   5164 N N   . ARG B 1 316 ? 125.644 38.292  197.877 1.00 75.64  ? 313 ARG B N   1 
ATOM   5165 C CA  . ARG B 1 316 ? 125.387 37.452  199.038 1.00 71.28  ? 313 ARG B CA  1 
ATOM   5166 C C   . ARG B 1 316 ? 123.906 37.388  199.351 1.00 77.25  ? 313 ARG B C   1 
ATOM   5167 O O   . ARG B 1 316 ? 123.533 37.076  200.483 1.00 84.59  ? 313 ARG B O   1 
ATOM   5168 C CB  . ARG B 1 316 ? 126.110 37.944  200.301 1.00 73.23  ? 313 ARG B CB  1 
ATOM   5169 C CG  . ARG B 1 316 ? 127.589 38.291  200.217 1.00 78.99  ? 313 ARG B CG  1 
ATOM   5170 C CD  . ARG B 1 316 ? 128.265 38.300  201.606 1.00 78.76  ? 313 ARG B CD  1 
ATOM   5171 N NE  . ARG B 1 316 ? 127.812 39.340  202.525 1.00 79.04  ? 313 ARG B NE  1 
ATOM   5172 C CZ  . ARG B 1 316 ? 128.382 40.528  202.680 1.00 81.14  ? 313 ARG B CZ  1 
ATOM   5173 N NH1 . ARG B 1 316 ? 129.393 40.916  201.913 1.00 76.14  ? 313 ARG B NH1 1 
ATOM   5174 N NH2 . ARG B 1 316 ? 127.944 41.336  203.647 1.00 75.95  ? 313 ARG B NH2 1 
ATOM   5175 N N   . GLN B 1 317 ? 123.059 37.764  198.403 1.00 77.93  ? 314 GLN B N   1 
ATOM   5176 C CA  . GLN B 1 317 ? 121.610 37.715  198.552 1.00 78.15  ? 314 GLN B CA  1 
ATOM   5177 C C   . GLN B 1 317 ? 121.103 38.554  199.734 1.00 74.72  ? 314 GLN B C   1 
ATOM   5178 O O   . GLN B 1 317 ? 119.937 38.414  200.131 1.00 80.69  ? 314 GLN B O   1 
ATOM   5179 C CB  . GLN B 1 317 ? 121.112 36.265  198.664 1.00 76.78  ? 314 GLN B CB  1 
ATOM   5180 C CG  . GLN B 1 317 ? 121.570 35.353  197.529 1.00 79.71  ? 314 GLN B CG  1 
ATOM   5181 C CD  . GLN B 1 317 ? 121.067 35.824  196.170 1.00 90.84  ? 314 GLN B CD  1 
ATOM   5182 O OE1 . GLN B 1 317 ? 119.864 35.777  195.878 1.00 88.86  ? 314 GLN B OE1 1 
ATOM   5183 N NE2 . GLN B 1 317 ? 121.997 36.285  195.325 1.00 87.67  ? 314 GLN B NE2 1 
ATOM   5184 N N   . GLU B 1 318 ? 121.945 39.416  200.324 1.00 63.63  ? 315 GLU B N   1 
ATOM   5185 C CA  . GLU B 1 318 ? 121.464 40.347  201.338 1.00 67.34  ? 315 GLU B CA  1 
ATOM   5186 C C   . GLU B 1 318 ? 120.786 41.576  200.756 1.00 66.14  ? 315 GLU B C   1 
ATOM   5187 O O   . GLU B 1 318 ? 120.118 42.299  201.502 1.00 65.86  ? 315 GLU B O   1 
ATOM   5188 C CB  . GLU B 1 318 ? 122.586 40.853  202.238 1.00 70.22  ? 315 GLU B CB  1 
ATOM   5189 C CG  . GLU B 1 318 ? 123.367 39.862  203.026 1.00 74.88  ? 315 GLU B CG  1 
ATOM   5190 C CD  . GLU B 1 318 ? 124.280 40.606  203.983 1.00 83.21  ? 315 GLU B CD  1 
ATOM   5191 O OE1 . GLU B 1 318 ? 123.733 41.344  204.847 1.00 79.23  ? 315 GLU B OE1 1 
ATOM   5192 O OE2 . GLU B 1 318 ? 125.524 40.451  203.887 1.00 84.96  ? 315 GLU B OE2 1 
ATOM   5193 N N   . LEU B 1 319 ? 120.989 41.837  199.473 1.00 65.78  ? 316 LEU B N   1 
ATOM   5194 C CA  . LEU B 1 319 ? 120.370 42.981  198.834 1.00 60.85  ? 316 LEU B CA  1 
ATOM   5195 C C   . LEU B 1 319 ? 119.816 42.622  197.489 1.00 62.37  ? 316 LEU B C   1 
ATOM   5196 O O   . LEU B 1 319 ? 120.535 42.139  196.634 1.00 64.46  ? 316 LEU B O   1 
ATOM   5197 C CB  . LEU B 1 319 ? 121.360 44.115  198.668 1.00 65.50  ? 316 LEU B CB  1 
ATOM   5198 C CG  . LEU B 1 319 ? 121.401 45.193  199.741 1.00 62.78  ? 316 LEU B CG  1 
ATOM   5199 C CD1 . LEU B 1 319 ? 121.760 46.529  199.117 1.00 57.01  ? 316 LEU B CD1 1 
ATOM   5200 C CD2 . LEU B 1 319 ? 120.057 45.274  200.433 1.00 61.33  ? 316 LEU B CD2 1 
ATOM   5201 N N   . VAL B 1 320 ? 118.529 42.836  197.304 1.00 63.57  ? 317 VAL B N   1 
ATOM   5202 C CA  . VAL B 1 320 ? 117.862 42.579  196.036 1.00 59.30  ? 317 VAL B CA  1 
ATOM   5203 C C   . VAL B 1 320 ? 117.952 43.843  195.205 1.00 62.62  ? 317 VAL B C   1 
ATOM   5204 O O   . VAL B 1 320 ? 117.649 44.937  195.690 1.00 64.66  ? 317 VAL B O   1 
ATOM   5205 C CB  . VAL B 1 320 ? 116.408 42.147  196.253 1.00 55.47  ? 317 VAL B CB  1 
ATOM   5206 C CG1 . VAL B 1 320 ? 115.666 42.080  194.940 1.00 62.48  ? 317 VAL B CG1 1 
ATOM   5207 C CG2 . VAL B 1 320 ? 116.396 40.799  196.920 1.00 61.15  ? 317 VAL B CG2 1 
ATOM   5208 N N   . ALA B 1 321 ? 118.396 43.699  193.962 1.00 62.90  ? 318 ALA B N   1 
ATOM   5209 C CA  . ALA B 1 321 ? 118.572 44.824  193.050 1.00 63.30  ? 318 ALA B CA  1 
ATOM   5210 C C   . ALA B 1 321 ? 118.039 44.337  191.706 1.00 67.58  ? 318 ALA B C   1 
ATOM   5211 O O   . ALA B 1 321 ? 118.772 43.742  190.911 1.00 72.21  ? 318 ALA B O   1 
ATOM   5212 C CB  . ALA B 1 321 ? 120.027 45.260  192.982 1.00 65.07  ? 318 ALA B CB  1 
ATOM   5213 N N   . HIS B 1 322 ? 116.749 44.549  191.489 1.00 62.17  ? 319 HIS B N   1 
ATOM   5214 C CA  . HIS B 1 322 ? 116.048 43.996  190.346 1.00 65.18  ? 319 HIS B CA  1 
ATOM   5215 C C   . HIS B 1 322 ? 116.182 44.899  189.125 1.00 70.33  ? 319 HIS B C   1 
ATOM   5216 O O   . HIS B 1 322 ? 116.397 46.108  189.244 1.00 74.05  ? 319 HIS B O   1 
ATOM   5217 C CB  . HIS B 1 322 ? 114.578 43.786  190.711 1.00 74.11  ? 319 HIS B CB  1 
ATOM   5218 C CG  . HIS B 1 322 ? 114.311 42.490  191.411 1.00 74.37  ? 319 HIS B CG  1 
ATOM   5219 N ND1 . HIS B 1 322 ? 113.172 42.263  192.150 1.00 82.01  ? 319 HIS B ND1 1 
ATOM   5220 C CD2 . HIS B 1 322 ? 115.027 41.341  191.459 1.00 72.32  ? 319 HIS B CD2 1 
ATOM   5221 C CE1 . HIS B 1 322 ? 113.201 41.033  192.631 1.00 84.72  ? 319 HIS B CE1 1 
ATOM   5222 N NE2 . HIS B 1 322 ? 114.314 40.450  192.221 1.00 76.90  ? 319 HIS B NE2 1 
ATOM   5223 N N   . GLU B 1 323 ? 116.053 44.299  187.942 1.00 68.37  ? 320 GLU B N   1 
ATOM   5224 C CA  . GLU B 1 323 ? 116.144 45.056  186.700 1.00 71.11  ? 320 GLU B CA  1 
ATOM   5225 C C   . GLU B 1 323 ? 115.244 44.428  185.641 1.00 70.36  ? 320 GLU B C   1 
ATOM   5226 O O   . GLU B 1 323 ? 115.118 43.203  185.563 1.00 73.31  ? 320 GLU B O   1 
ATOM   5227 C CB  . GLU B 1 323 ? 117.590 45.127  186.179 1.00 70.52  ? 320 GLU B CB  1 
ATOM   5228 C CG  . GLU B 1 323 ? 118.159 43.810  185.654 1.00 68.81  ? 320 GLU B CG  1 
ATOM   5229 C CD  . GLU B 1 323 ? 119.594 43.942  185.161 1.00 71.05  ? 320 GLU B CD  1 
ATOM   5230 O OE1 . GLU B 1 323 ? 120.148 45.068  185.196 1.00 69.36  ? 320 GLU B OE1 1 
ATOM   5231 O OE2 . GLU B 1 323 ? 120.163 42.917  184.720 1.00 73.33  ? 320 GLU B OE2 1 
ATOM   5232 N N   . THR B 1 324 ? 114.689 45.287  184.776 1.00 66.88  ? 321 THR B N   1 
ATOM   5233 C CA  . THR B 1 324 ? 113.701 44.949  183.744 1.00 63.30  ? 321 THR B CA  1 
ATOM   5234 C C   . THR B 1 324 ? 114.312 45.262  182.377 1.00 69.97  ? 321 THR B C   1 
ATOM   5235 O O   . THR B 1 324 ? 114.284 46.418  181.933 1.00 67.86  ? 321 THR B O   1 
ATOM   5236 C CB  . THR B 1 324 ? 112.422 45.770  183.956 1.00 62.97  ? 321 THR B CB  1 
ATOM   5237 O OG1 . THR B 1 324 ? 111.849 45.479  185.236 1.00 78.08  ? 321 THR B OG1 1 
ATOM   5238 C CG2 . THR B 1 324 ? 111.411 45.495  182.895 1.00 62.28  ? 321 THR B CG2 1 
ATOM   5239 N N   . VAL B 1 325 ? 114.820 44.248  181.675 1.00 65.13  ? 322 VAL B N   1 
ATOM   5240 C CA  . VAL B 1 325 ? 115.600 44.465  180.459 1.00 61.55  ? 322 VAL B CA  1 
ATOM   5241 C C   . VAL B 1 325 ? 114.701 44.226  179.251 1.00 62.26  ? 322 VAL B C   1 
ATOM   5242 O O   . VAL B 1 325 ? 114.517 43.091  178.804 1.00 63.82  ? 322 VAL B O   1 
ATOM   5243 C CB  . VAL B 1 325 ? 116.845 43.578  180.428 1.00 65.69  ? 322 VAL B CB  1 
ATOM   5244 C CG1 . VAL B 1 325 ? 117.767 43.975  179.277 1.00 64.27  ? 322 VAL B CG1 1 
ATOM   5245 C CG2 . VAL B 1 325 ? 117.568 43.699  181.734 1.00 68.83  ? 322 VAL B CG2 1 
ATOM   5246 N N   . GLN B 1 326 ? 114.152 45.313  178.712 1.00 66.44  ? 323 GLN B N   1 
ATOM   5247 C CA  . GLN B 1 326 ? 113.548 45.292  177.386 1.00 68.00  ? 323 GLN B CA  1 
ATOM   5248 C C   . GLN B 1 326 ? 114.613 45.005  176.334 1.00 65.61  ? 323 GLN B C   1 
ATOM   5249 O O   . GLN B 1 326 ? 115.782 45.351  176.500 1.00 65.69  ? 323 GLN B O   1 
ATOM   5250 C CB  . GLN B 1 326 ? 112.890 46.645  177.103 1.00 64.04  ? 323 GLN B CB  1 
ATOM   5251 C CG  . GLN B 1 326 ? 112.023 46.679  175.874 1.00 76.11  ? 323 GLN B CG  1 
ATOM   5252 C CD  . GLN B 1 326 ? 110.901 45.656  175.935 1.00 85.05  ? 323 GLN B CD  1 
ATOM   5253 O OE1 . GLN B 1 326 ? 111.038 44.522  175.437 1.00 79.63  ? 323 GLN B OE1 1 
ATOM   5254 N NE2 . GLN B 1 326 ? 109.781 46.046  176.555 1.00 79.43  ? 323 GLN B NE2 1 
ATOM   5255 N N   . ASP B 1 327 ? 114.199 44.420  175.211 1.00 68.66  ? 324 ASP B N   1 
ATOM   5256 C CA  . ASP B 1 327 ? 115.143 44.069  174.154 1.00 67.72  ? 324 ASP B CA  1 
ATOM   5257 C C   . ASP B 1 327 ? 114.754 44.755  172.851 1.00 65.70  ? 324 ASP B C   1 
ATOM   5258 O O   . ASP B 1 327 ? 113.573 44.862  172.510 1.00 69.21  ? 324 ASP B O   1 
ATOM   5259 C CB  . ASP B 1 327 ? 115.227 42.545  173.950 1.00 64.90  ? 324 ASP B CB  1 
ATOM   5260 C CG  . ASP B 1 327 ? 116.101 41.856  174.997 1.00 77.66  ? 324 ASP B CG  1 
ATOM   5261 O OD1 . ASP B 1 327 ? 115.611 41.614  176.129 1.00 83.15  ? 324 ASP B OD1 1 
ATOM   5262 O OD2 . ASP B 1 327 ? 117.281 41.555  174.697 1.00 78.73  ? 324 ASP B OD2 1 
ATOM   5263 N N   . GLY B 1 328 ? 115.756 45.193  172.115 1.00 58.33  ? 325 GLY B N   1 
ATOM   5264 C CA  . GLY B 1 328 ? 115.499 45.803  170.838 1.00 62.93  ? 325 GLY B CA  1 
ATOM   5265 C C   . GLY B 1 328 ? 115.605 47.314  170.816 1.00 63.90  ? 325 GLY B C   1 
ATOM   5266 O O   . GLY B 1 328 ? 114.861 48.029  171.490 1.00 62.04  ? 325 GLY B O   1 
ATOM   5267 N N   . PHE B 1 329 ? 116.514 47.800  169.971 1.00 64.51  ? 326 PHE B N   1 
ATOM   5268 C CA  . PHE B 1 329 ? 116.731 49.229  169.815 1.00 58.63  ? 326 PHE B CA  1 
ATOM   5269 C C   . PHE B 1 329 ? 115.465 49.932  169.366 1.00 59.03  ? 326 PHE B C   1 
ATOM   5270 O O   . PHE B 1 329 ? 115.269 51.114  169.656 1.00 61.46  ? 326 PHE B O   1 
ATOM   5271 C CB  . PHE B 1 329 ? 117.866 49.446  168.820 1.00 56.73  ? 326 PHE B CB  1 
ATOM   5272 C CG  . PHE B 1 329 ? 118.288 50.874  168.669 1.00 59.97  ? 326 PHE B CG  1 
ATOM   5273 C CD1 . PHE B 1 329 ? 119.205 51.431  169.542 1.00 60.68  ? 326 PHE B CD1 1 
ATOM   5274 C CD2 . PHE B 1 329 ? 117.783 51.655  167.645 1.00 61.66  ? 326 PHE B CD2 1 
ATOM   5275 C CE1 . PHE B 1 329 ? 119.602 52.751  169.398 1.00 65.48  ? 326 PHE B CE1 1 
ATOM   5276 C CE2 . PHE B 1 329 ? 118.174 52.971  167.491 1.00 62.51  ? 326 PHE B CE2 1 
ATOM   5277 C CZ  . PHE B 1 329 ? 119.080 53.524  168.367 1.00 64.46  ? 326 PHE B CZ  1 
ATOM   5278 N N   . GLU B 1 330 ? 114.623 49.235  168.611 1.00 62.76  ? 327 GLU B N   1 
ATOM   5279 C CA  . GLU B 1 330 ? 113.389 49.818  168.104 1.00 66.82  ? 327 GLU B CA  1 
ATOM   5280 C C   . GLU B 1 330 ? 112.445 50.220  169.228 1.00 68.35  ? 327 GLU B C   1 
ATOM   5281 O O   . GLU B 1 330 ? 111.615 51.119  169.038 1.00 69.13  ? 327 GLU B O   1 
ATOM   5282 C CB  . GLU B 1 330 ? 112.715 48.818  167.148 1.00 71.02  ? 327 GLU B CB  1 
ATOM   5283 C CG  . GLU B 1 330 ? 112.449 47.413  167.733 1.00 69.36  ? 327 GLU B CG  1 
ATOM   5284 C CD  . GLU B 1 330 ? 113.455 46.331  167.292 1.00 73.39  ? 327 GLU B CD  1 
ATOM   5285 O OE1 . GLU B 1 330 ? 114.453 46.639  166.599 1.00 79.18  ? 327 GLU B OE1 1 
ATOM   5286 O OE2 . GLU B 1 330 ? 113.236 45.149  167.633 1.00 73.58  ? 327 GLU B OE2 1 
ATOM   5287 N N   . HIS B 1 331 ? 112.575 49.595  170.398 1.00 66.90  ? 328 HIS B N   1 
ATOM   5288 C CA  . HIS B 1 331 ? 111.625 49.735  171.490 1.00 67.27  ? 328 HIS B CA  1 
ATOM   5289 C C   . HIS B 1 331 ? 112.092 50.688  172.576 1.00 69.98  ? 328 HIS B C   1 
ATOM   5290 O O   . HIS B 1 331 ? 111.462 50.739  173.637 1.00 71.61  ? 328 HIS B O   1 
ATOM   5291 C CB  . HIS B 1 331 ? 111.373 48.370  172.103 1.00 64.68  ? 328 HIS B CB  1 
ATOM   5292 C CG  . HIS B 1 331 ? 110.876 47.378  171.114 1.00 70.49  ? 328 HIS B CG  1 
ATOM   5293 N ND1 . HIS B 1 331 ? 111.336 46.081  171.067 1.00 75.65  ? 328 HIS B ND1 1 
ATOM   5294 C CD2 . HIS B 1 331 ? 109.993 47.505  170.098 1.00 67.95  ? 328 HIS B CD2 1 
ATOM   5295 C CE1 . HIS B 1 331 ? 110.739 45.442  170.078 1.00 71.05  ? 328 HIS B CE1 1 
ATOM   5296 N NE2 . HIS B 1 331 ? 109.917 46.284  169.476 1.00 69.94  ? 328 HIS B NE2 1 
ATOM   5297 N N   . ILE B 1 332 ? 113.178 51.436  172.347 1.00 66.71  ? 329 ILE B N   1 
ATOM   5298 C CA  . ILE B 1 332 ? 113.744 52.264  173.414 1.00 64.69  ? 329 ILE B CA  1 
ATOM   5299 C C   . ILE B 1 332 ? 112.720 53.259  173.958 1.00 67.15  ? 329 ILE B C   1 
ATOM   5300 O O   . ILE B 1 332 ? 112.526 53.298  175.185 1.00 70.88  ? 329 ILE B O   1 
ATOM   5301 C CB  . ILE B 1 332 ? 115.052 52.915  172.947 1.00 64.77  ? 329 ILE B CB  1 
ATOM   5302 C CG1 . ILE B 1 332 ? 116.163 51.855  172.862 1.00 59.34  ? 329 ILE B CG1 1 
ATOM   5303 C CG2 . ILE B 1 332 ? 115.444 54.065  173.859 1.00 58.29  ? 329 ILE B CG2 1 
ATOM   5304 C CD1 . ILE B 1 332 ? 117.510 52.382  172.422 1.00 53.66  ? 329 ILE B CD1 1 
ATOM   5305 N N   . PRO B 1 333 ? 112.017 54.046  173.136 1.00 65.31  ? 330 PRO B N   1 
ATOM   5306 C CA  . PRO B 1 333 ? 110.977 54.914  173.719 1.00 69.42  ? 330 PRO B CA  1 
ATOM   5307 C C   . PRO B 1 333 ? 109.766 54.134  174.241 1.00 66.18  ? 330 PRO B C   1 
ATOM   5308 O O   . PRO B 1 333 ? 109.132 54.561  175.215 1.00 62.90  ? 330 PRO B O   1 
ATOM   5309 C CB  . PRO B 1 333 ? 110.621 55.864  172.562 1.00 65.56  ? 330 PRO B CB  1 
ATOM   5310 C CG  . PRO B 1 333 ? 111.782 55.785  171.629 1.00 65.29  ? 330 PRO B CG  1 
ATOM   5311 C CD  . PRO B 1 333 ? 112.214 54.352  171.710 1.00 65.50  ? 330 PRO B CD  1 
ATOM   5312 N N   . ALA B 1 334 ? 109.419 53.009  173.616 1.00 64.73  ? 331 ALA B N   1 
ATOM   5313 C CA  . ALA B 1 334 ? 108.406 52.133  174.190 1.00 66.05  ? 331 ALA B CA  1 
ATOM   5314 C C   . ALA B 1 334 ? 108.752 51.782  175.626 1.00 71.15  ? 331 ALA B C   1 
ATOM   5315 O O   . ALA B 1 334 ? 107.912 51.895  176.526 1.00 74.51  ? 331 ALA B O   1 
ATOM   5316 C CB  . ALA B 1 334 ? 108.270 50.863  173.350 1.00 69.94  ? 331 ALA B CB  1 
ATOM   5317 N N   . ALA B 1 335 ? 109.986 51.317  175.847 1.00 69.65  ? 332 ALA B N   1 
ATOM   5318 C CA  . ALA B 1 335 ? 110.443 50.987  177.191 1.00 67.68  ? 332 ALA B CA  1 
ATOM   5319 C C   . ALA B 1 335 ? 110.479 52.225  178.074 1.00 67.06  ? 332 ALA B C   1 
ATOM   5320 O O   . ALA B 1 335 ? 110.159 52.161  179.267 1.00 65.22  ? 332 ALA B O   1 
ATOM   5321 C CB  . ALA B 1 335 ? 111.819 50.329  177.127 1.00 69.25  ? 332 ALA B CB  1 
ATOM   5322 N N   . TYR B 1 336 ? 110.879 53.361  177.504 1.00 68.50  ? 333 TYR B N   1 
ATOM   5323 C CA  . TYR B 1 336 ? 110.892 54.608  178.260 1.00 70.15  ? 333 TYR B CA  1 
ATOM   5324 C C   . TYR B 1 336 ? 109.493 54.967  178.732 1.00 71.98  ? 333 TYR B C   1 
ATOM   5325 O O   . TYR B 1 336 ? 109.302 55.352  179.890 1.00 72.31  ? 333 TYR B O   1 
ATOM   5326 C CB  . TYR B 1 336 ? 111.456 55.717  177.382 1.00 63.54  ? 333 TYR B CB  1 
ATOM   5327 C CG  . TYR B 1 336 ? 111.393 57.121  177.923 1.00 66.25  ? 333 TYR B CG  1 
ATOM   5328 C CD1 . TYR B 1 336 ? 112.222 57.540  178.963 1.00 70.64  ? 333 TYR B CD1 1 
ATOM   5329 C CD2 . TYR B 1 336 ? 110.524 58.047  177.369 1.00 68.56  ? 333 TYR B CD2 1 
ATOM   5330 C CE1 . TYR B 1 336 ? 112.177 58.862  179.432 1.00 70.73  ? 333 TYR B CE1 1 
ATOM   5331 C CE2 . TYR B 1 336 ? 110.467 59.358  177.826 1.00 71.58  ? 333 TYR B CE2 1 
ATOM   5332 C CZ  . TYR B 1 336 ? 111.289 59.766  178.850 1.00 71.45  ? 333 TYR B CZ  1 
ATOM   5333 O OH  . TYR B 1 336 ? 111.206 61.075  179.280 1.00 66.70  ? 333 TYR B OH  1 
ATOM   5334 N N   . GLN B 1 337 ? 108.495 54.788  177.859 1.00 73.43  ? 334 GLN B N   1 
ATOM   5335 C CA  . GLN B 1 337 ? 107.126 55.188  178.171 1.00 72.87  ? 334 GLN B CA  1 
ATOM   5336 C C   . GLN B 1 337 ? 106.557 54.429  179.366 1.00 72.27  ? 334 GLN B C   1 
ATOM   5337 O O   . GLN B 1 337 ? 105.662 54.938  180.054 1.00 71.81  ? 334 GLN B O   1 
ATOM   5338 C CB  . GLN B 1 337 ? 106.231 54.983  176.950 1.00 70.97  ? 334 GLN B CB  1 
ATOM   5339 C CG  . GLN B 1 337 ? 104.846 55.590  177.097 1.00 72.37  ? 334 GLN B CG  1 
ATOM   5340 C CD  . GLN B 1 337 ? 104.864 57.094  176.966 1.00 76.16  ? 334 GLN B CD  1 
ATOM   5341 O OE1 . GLN B 1 337 ? 105.048 57.629  175.870 1.00 79.90  ? 334 GLN B OE1 1 
ATOM   5342 N NE2 . GLN B 1 337 ? 104.697 57.789  178.085 1.00 74.96  ? 334 GLN B NE2 1 
ATOM   5343 N N   . THR B 1 338 ? 107.043 53.215  179.625 1.00 65.87  ? 335 THR B N   1 
ATOM   5344 C CA  . THR B 1 338 ? 106.497 52.450  180.739 1.00 70.13  ? 335 THR B CA  1 
ATOM   5345 C C   . THR B 1 338 ? 106.790 53.118  182.083 1.00 74.58  ? 335 THR B C   1 
ATOM   5346 O O   . THR B 1 338 ? 106.029 52.935  183.044 1.00 71.11  ? 335 THR B O   1 
ATOM   5347 C CB  . THR B 1 338 ? 107.028 51.015  180.699 1.00 71.45  ? 335 THR B CB  1 
ATOM   5348 O OG1 . THR B 1 338 ? 108.355 50.967  181.230 1.00 75.99  ? 335 THR B OG1 1 
ATOM   5349 C CG2 . THR B 1 338 ? 107.036 50.474  179.288 1.00 65.23  ? 335 THR B CG2 1 
ATOM   5350 N N   . LEU B 1 339 ? 107.864 53.915  182.162 1.00 77.09  ? 336 LEU B N   1 
ATOM   5351 C CA  . LEU B 1 339 ? 108.201 54.608  183.407 1.00 74.87  ? 336 LEU B CA  1 
ATOM   5352 C C   . LEU B 1 339 ? 107.082 55.548  183.836 1.00 76.25  ? 336 LEU B C   1 
ATOM   5353 O O   . LEU B 1 339 ? 106.791 55.686  185.030 1.00 79.69  ? 336 LEU B O   1 
ATOM   5354 C CB  . LEU B 1 339 ? 109.498 55.407  183.228 1.00 70.28  ? 336 LEU B CB  1 
ATOM   5355 C CG  . LEU B 1 339 ? 110.778 54.694  182.782 1.00 66.59  ? 336 LEU B CG  1 
ATOM   5356 C CD1 . LEU B 1 339 ? 111.969 55.625  182.790 1.00 64.17  ? 336 LEU B CD1 1 
ATOM   5357 C CD2 . LEU B 1 339 ? 111.051 53.508  183.662 1.00 59.79  ? 336 LEU B CD2 1 
ATOM   5358 N N   . PHE B 1 340 ? 106.421 56.172  182.872 1.00 76.17  ? 337 PHE B N   1 
ATOM   5359 C CA  . PHE B 1 340 ? 105.354 57.117  183.137 1.00 77.94  ? 337 PHE B CA  1 
ATOM   5360 C C   . PHE B 1 340 ? 103.974 56.499  183.027 1.00 83.32  ? 337 PHE B C   1 
ATOM   5361 O O   . PHE B 1 340 ? 102.980 57.195  183.251 1.00 83.24  ? 337 PHE B O   1 
ATOM   5362 C CB  . PHE B 1 340 ? 105.459 58.280  182.180 1.00 73.25  ? 337 PHE B CB  1 
ATOM   5363 C CG  . PHE B 1 340 ? 106.834 58.792  182.020 1.00 74.33  ? 337 PHE B CG  1 
ATOM   5364 C CD1 . PHE B 1 340 ? 107.341 59.727  182.895 1.00 77.14  ? 337 PHE B CD1 1 
ATOM   5365 C CD2 . PHE B 1 340 ? 107.626 58.343  180.984 1.00 76.91  ? 337 PHE B CD2 1 
ATOM   5366 C CE1 . PHE B 1 340 ? 108.625 60.213  182.736 1.00 77.75  ? 337 PHE B CE1 1 
ATOM   5367 C CE2 . PHE B 1 340 ? 108.902 58.822  180.814 1.00 76.55  ? 337 PHE B CE2 1 
ATOM   5368 C CZ  . PHE B 1 340 ? 109.408 59.757  181.692 1.00 75.63  ? 337 PHE B CZ  1 
ATOM   5369 N N   . SER B 1 341 ? 103.895 55.219  182.677 1.00 87.91  ? 338 SER B N   1 
ATOM   5370 C CA  . SER B 1 341 ? 102.613 54.541  182.568 1.00 90.43  ? 338 SER B CA  1 
ATOM   5371 C C   . SER B 1 341 ? 101.964 54.436  183.928 1.00 90.46  ? 338 SER B C   1 
ATOM   5372 O O   . SER B 1 341 ? 102.641 54.223  184.941 1.00 92.19  ? 338 SER B O   1 
ATOM   5373 C CB  . SER B 1 341 ? 102.780 53.126  182.014 1.00 92.52  ? 338 SER B CB  1 
ATOM   5374 O OG  . SER B 1 341 ? 102.784 52.172  183.070 1.00 83.55  ? 338 SER B OG  1 
ATOM   5375 N N   . ALA B 1 342 ? 100.640 54.602  183.949 1.00 94.03  ? 339 ALA B N   1 
ATOM   5376 C CA  . ALA B 1 342 ? 99.941  54.456  185.211 1.00 101.76 ? 339 ALA B CA  1 
ATOM   5377 C C   . ALA B 1 342 ? 99.918  52.997  185.655 1.00 107.79 ? 339 ALA B C   1 
ATOM   5378 O O   . ALA B 1 342 ? 99.777  52.732  186.854 1.00 104.66 ? 339 ALA B O   1 
ATOM   5379 C CB  . ALA B 1 342 ? 98.518  55.022  185.095 1.00 90.08  ? 339 ALA B CB  1 
ATOM   5380 N N   . SER B 1 343 ? 100.087 52.048  184.725 1.00 106.56 ? 340 SER B N   1 
ATOM   5381 C CA  . SER B 1 343 ? 100.285 50.657  185.116 1.00 99.69  ? 340 SER B CA  1 
ATOM   5382 C C   . SER B 1 343 ? 101.656 50.507  185.768 1.00 102.01 ? 340 SER B C   1 
ATOM   5383 O O   . SER B 1 343 ? 102.629 51.161  185.373 1.00 102.06 ? 340 SER B O   1 
ATOM   5384 C CB  . SER B 1 343 ? 100.166 49.729  183.907 1.00 94.50  ? 340 SER B CB  1 
ATOM   5385 O OG  . SER B 1 343 ? 98.927  49.911  183.252 1.00 92.15  ? 340 SER B OG  1 
ATOM   5386 N N   . GLU B 1 344 ? 101.731 49.637  186.770 1.00 102.07 ? 341 GLU B N   1 
ATOM   5387 C CA  . GLU B 1 344 ? 102.971 49.434  187.517 1.00 106.86 ? 341 GLU B CA  1 
ATOM   5388 C C   . GLU B 1 344 ? 103.650 48.108  187.218 1.00 102.45 ? 341 GLU B C   1 
ATOM   5389 O O   . GLU B 1 344 ? 104.054 47.398  188.147 1.00 105.59 ? 341 GLU B O   1 
ATOM   5390 C CB  . GLU B 1 344 ? 102.752 49.590  189.031 1.00 103.76 ? 341 GLU B CB  1 
ATOM   5391 C CG  . GLU B 1 344 ? 102.463 51.035  189.451 1.00 100.48 ? 341 GLU B CG  1 
ATOM   5392 C CD  . GLU B 1 344 ? 100.995 51.366  189.565 1.00 104.12 ? 341 GLU B CD  1 
ATOM   5393 O OE1 . GLU B 1 344 ? 100.195 50.881  188.730 1.00 105.74 ? 341 GLU B OE1 1 
ATOM   5394 O OE2 . GLU B 1 344 ? 100.649 52.150  190.477 1.00 104.31 ? 341 GLU B OE2 1 
ATOM   5395 N N   . SER B 1 345 ? 103.791 47.756  185.947 1.00 93.45  ? 342 SER B N   1 
ATOM   5396 C CA  . SER B 1 345 ? 104.250 46.413  185.640 1.00 92.97  ? 342 SER B CA  1 
ATOM   5397 C C   . SER B 1 345 ? 105.766 46.249  185.752 1.00 94.03  ? 342 SER B C   1 
ATOM   5398 O O   . SER B 1 345 ? 106.238 45.107  185.733 1.00 90.96  ? 342 SER B O   1 
ATOM   5399 C CB  . SER B 1 345 ? 103.795 46.045  184.229 1.00 98.84  ? 342 SER B CB  1 
ATOM   5400 O OG  . SER B 1 345 ? 104.082 47.108  183.328 1.00 95.19  ? 342 SER B OG  1 
ATOM   5401 N N   . ASN B 1 346 ? 106.520 47.335  185.978 1.00 94.58  ? 343 ASN B N   1 
ATOM   5402 C CA  . ASN B 1 346 ? 107.986 47.340  185.956 1.00 91.99  ? 343 ASN B CA  1 
ATOM   5403 C C   . ASN B 1 346 ? 108.581 47.238  187.358 1.00 94.94  ? 343 ASN B C   1 
ATOM   5404 O O   . ASN B 1 346 ? 108.093 47.872  188.296 1.00 100.88 ? 343 ASN B O   1 
ATOM   5405 C CB  . ASN B 1 346 ? 108.530 48.604  185.277 1.00 87.73  ? 343 ASN B CB  1 
ATOM   5406 C CG  . ASN B 1 346 ? 108.455 48.547  183.744 1.00 89.84  ? 343 ASN B CG  1 
ATOM   5407 O OD1 . ASN B 1 346 ? 108.358 49.585  183.081 1.00 80.80  ? 343 ASN B OD1 1 
ATOM   5408 N ND2 . ASN B 1 346 ? 108.519 47.337  183.181 1.00 86.07  ? 343 ASN B ND2 1 
ATOM   5409 N N   . ARG B 1 347 ? 109.646 46.437  187.494 1.00 88.70  ? 344 ARG B N   1 
ATOM   5410 C CA  . ARG B 1 347 ? 110.364 46.264  188.756 1.00 85.63  ? 344 ARG B CA  1 
ATOM   5411 C C   . ARG B 1 347 ? 111.860 46.519  188.593 1.00 80.60  ? 344 ARG B C   1 
ATOM   5412 O O   . ARG B 1 347 ? 112.501 45.964  187.694 1.00 70.92  ? 344 ARG B O   1 
ATOM   5413 C CB  . ARG B 1 347 ? 110.134 44.855  189.331 1.00 85.59  ? 344 ARG B CB  1 
ATOM   5414 C CG  . ARG B 1 347 ? 108.968 44.772  190.321 1.00 92.19  ? 344 ARG B CG  1 
ATOM   5415 C CD  . ARG B 1 347 ? 107.840 43.867  189.831 1.00 93.81  ? 344 ARG B CD  1 
ATOM   5416 N NE  . ARG B 1 347 ? 106.600 44.093  190.570 1.00 95.62  ? 344 ARG B NE  1 
ATOM   5417 C CZ  . ARG B 1 347 ? 105.775 45.108  190.347 1.00 95.96  ? 344 ARG B CZ  1 
ATOM   5418 N NH1 . ARG B 1 347 ? 106.033 46.018  189.421 1.00 98.32  ? 344 ARG B NH1 1 
ATOM   5419 N NH2 . ARG B 1 347 ? 104.658 45.208  191.062 1.00 92.32  ? 344 ARG B NH2 1 
ATOM   5420 N N   . GLY B 1 348 ? 112.417 47.329  189.499 1.00 86.19  ? 345 GLY B N   1 
ATOM   5421 C CA  . GLY B 1 348 ? 113.826 47.680  189.489 1.00 72.57  ? 345 GLY B CA  1 
ATOM   5422 C C   . GLY B 1 348 ? 114.171 48.596  188.332 1.00 72.20  ? 345 GLY B C   1 
ATOM   5423 O O   . GLY B 1 348 ? 113.343 49.380  187.863 1.00 75.73  ? 345 GLY B O   1 
ATOM   5424 N N   . LYS B 1 349 ? 115.431 48.530  187.895 1.00 70.49  ? 346 LYS B N   1 
ATOM   5425 C CA  . LYS B 1 349 ? 115.936 49.433  186.863 1.00 64.71  ? 346 LYS B CA  1 
ATOM   5426 C C   . LYS B 1 349 ? 115.459 48.994  185.481 1.00 64.83  ? 346 LYS B C   1 
ATOM   5427 O O   . LYS B 1 349 ? 115.410 47.800  185.187 1.00 69.40  ? 346 LYS B O   1 
ATOM   5428 C CB  . LYS B 1 349 ? 117.463 49.455  186.903 1.00 59.46  ? 346 LYS B CB  1 
ATOM   5429 C CG  . LYS B 1 349 ? 118.085 50.417  185.910 1.00 61.95  ? 346 LYS B CG  1 
ATOM   5430 C CD  . LYS B 1 349 ? 118.242 51.791  186.499 1.00 60.79  ? 346 LYS B CD  1 
ATOM   5431 C CE  . LYS B 1 349 ? 118.362 52.825  185.409 1.00 61.55  ? 346 LYS B CE  1 
ATOM   5432 N NZ  . LYS B 1 349 ? 117.031 53.038  184.757 1.00 66.10  ? 346 LYS B NZ  1 
ATOM   5433 N N   . VAL B 1 350 ? 115.164 49.955  184.606 1.00 62.71  ? 347 VAL B N   1 
ATOM   5434 C CA  . VAL B 1 350 ? 114.689 49.658  183.252 1.00 63.95  ? 347 VAL B CA  1 
ATOM   5435 C C   . VAL B 1 350 ? 115.802 49.966  182.247 1.00 68.35  ? 347 VAL B C   1 
ATOM   5436 O O   . VAL B 1 350 ? 116.292 51.103  182.169 1.00 63.57  ? 347 VAL B O   1 
ATOM   5437 C CB  . VAL B 1 350 ? 113.407 50.439  182.917 1.00 57.04  ? 347 VAL B CB  1 
ATOM   5438 C CG1 . VAL B 1 350 ? 112.744 49.869  181.701 1.00 58.15  ? 347 VAL B CG1 1 
ATOM   5439 C CG2 . VAL B 1 350 ? 112.468 50.373  184.063 1.00 63.44  ? 347 VAL B CG2 1 
ATOM   5440 N N   . LEU B 1 351 ? 116.173 48.950  181.457 1.00 65.29  ? 348 LEU B N   1 
ATOM   5441 C CA  . LEU B 1 351 ? 117.206 49.024  180.435 1.00 52.98  ? 348 LEU B CA  1 
ATOM   5442 C C   . LEU B 1 351 ? 116.676 48.421  179.153 1.00 58.11  ? 348 LEU B C   1 
ATOM   5443 O O   . LEU B 1 351 ? 115.747 47.618  179.173 1.00 62.80  ? 348 LEU B O   1 
ATOM   5444 C CB  . LEU B 1 351 ? 118.438 48.216  180.802 1.00 55.96  ? 348 LEU B CB  1 
ATOM   5445 C CG  . LEU B 1 351 ? 119.097 48.414  182.143 1.00 61.65  ? 348 LEU B CG  1 
ATOM   5446 C CD1 . LEU B 1 351 ? 120.030 47.249  182.364 1.00 58.76  ? 348 LEU B CD1 1 
ATOM   5447 C CD2 . LEU B 1 351 ? 119.837 49.731  182.129 1.00 62.68  ? 348 LEU B CD2 1 
ATOM   5448 N N   . VAL B 1 352 ? 117.330 48.759  178.046 1.00 60.40  ? 349 VAL B N   1 
ATOM   5449 C CA  . VAL B 1 352 ? 117.129 48.097  176.763 1.00 57.03  ? 349 VAL B CA  1 
ATOM   5450 C C   . VAL B 1 352 ? 118.438 47.428  176.352 1.00 59.14  ? 349 VAL B C   1 
ATOM   5451 O O   . VAL B 1 352 ? 119.524 47.987  176.543 1.00 57.62  ? 349 VAL B O   1 
ATOM   5452 C CB  . VAL B 1 352 ? 116.645 49.075  175.678 1.00 56.62  ? 349 VAL B CB  1 
ATOM   5453 C CG1 . VAL B 1 352 ? 116.636 48.382  174.337 1.00 63.20  ? 349 VAL B CG1 1 
ATOM   5454 C CG2 . VAL B 1 352 ? 115.255 49.580  175.997 1.00 56.14  ? 349 VAL B CG2 1 
ATOM   5455 N N   . ARG B 1 353 ? 118.342 46.220  175.813 1.00 59.50  ? 350 ARG B N   1 
ATOM   5456 C CA  . ARG B 1 353 ? 119.505 45.553  175.262 1.00 56.67  ? 350 ARG B CA  1 
ATOM   5457 C C   . ARG B 1 353 ? 119.519 45.773  173.761 1.00 63.49  ? 350 ARG B C   1 
ATOM   5458 O O   . ARG B 1 353 ? 118.486 45.667  173.093 1.00 67.93  ? 350 ARG B O   1 
ATOM   5459 C CB  . ARG B 1 353 ? 119.486 44.064  175.561 1.00 61.32  ? 350 ARG B CB  1 
ATOM   5460 C CG  . ARG B 1 353 ? 120.691 43.352  175.000 1.00 65.50  ? 350 ARG B CG  1 
ATOM   5461 C CD  . ARG B 1 353 ? 120.532 41.896  175.250 1.00 66.64  ? 350 ARG B CD  1 
ATOM   5462 N NE  . ARG B 1 353 ? 120.150 41.705  176.638 1.00 76.76  ? 350 ARG B NE  1 
ATOM   5463 C CZ  . ARG B 1 353 ? 119.641 40.586  177.123 1.00 89.04  ? 350 ARG B CZ  1 
ATOM   5464 N NH1 . ARG B 1 353 ? 119.411 39.542  176.341 1.00 83.11  ? 350 ARG B NH1 1 
ATOM   5465 N NH2 . ARG B 1 353 ? 119.365 40.511  178.428 1.00 89.53  ? 350 ARG B NH2 1 
ATOM   5466 N N   . VAL B 1 354 ? 120.653 46.169  173.223 1.00 61.45  ? 351 VAL B N   1 
ATOM   5467 C CA  . VAL B 1 354 ? 120.683 46.529  171.822 1.00 60.28  ? 351 VAL B CA  1 
ATOM   5468 C C   . VAL B 1 354 ? 121.684 45.715  171.049 1.00 63.85  ? 351 VAL B C   1 
ATOM   5469 O O   . VAL B 1 354 ? 121.306 44.823  170.303 1.00 72.99  ? 351 VAL B O   1 
ATOM   5470 C CB  . VAL B 1 354 ? 121.045 48.010  171.679 1.00 59.66  ? 351 VAL B CB  1 
ATOM   5471 C CG1 . VAL B 1 354 ? 121.103 48.403  170.217 1.00 61.69  ? 351 VAL B CG1 1 
ATOM   5472 C CG2 . VAL B 1 354 ? 120.066 48.882  172.445 1.00 56.53  ? 351 VAL B CG2 1 
HETATM 5473 P PA  . NAP C 2 .   ? 116.175 91.423  213.424 1.00 113.75 ? 501 NAP A PA  1 
HETATM 5474 O O1A . NAP C 2 .   ? 115.597 92.450  214.360 1.00 102.23 ? 501 NAP A O1A 1 
HETATM 5475 O O2A . NAP C 2 .   ? 117.305 91.783  212.502 1.00 101.88 ? 501 NAP A O2A 1 
HETATM 5476 O O5B . NAP C 2 .   ? 114.992 90.853  212.505 1.00 103.62 ? 501 NAP A O5B 1 
HETATM 5477 C C5B . NAP C 2 .   ? 114.101 91.752  211.855 1.00 93.65  ? 501 NAP A C5B 1 
HETATM 5478 C C4B . NAP C 2 .   ? 114.847 92.581  210.825 1.00 90.37  ? 501 NAP A C4B 1 
HETATM 5479 O O4B . NAP C 2 .   ? 114.582 92.079  209.518 1.00 91.21  ? 501 NAP A O4B 1 
HETATM 5480 C C3B . NAP C 2 .   ? 114.399 94.027  210.856 1.00 91.55  ? 501 NAP A C3B 1 
HETATM 5481 O O3B . NAP C 2 .   ? 115.393 94.839  211.480 1.00 91.74  ? 501 NAP A O3B 1 
HETATM 5482 C C2B . NAP C 2 .   ? 114.191 94.419  209.413 1.00 97.42  ? 501 NAP A C2B 1 
HETATM 5483 O O2B . NAP C 2 .   ? 115.243 95.250  208.946 1.00 98.10  ? 501 NAP A O2B 1 
HETATM 5484 C C1B . NAP C 2 .   ? 114.186 93.123  208.633 1.00 94.82  ? 501 NAP A C1B 1 
HETATM 5485 N N9A . NAP C 2 .   ? 112.819 92.860  208.145 1.00 86.52  ? 501 NAP A N9A 1 
HETATM 5486 C C8A . NAP C 2 .   ? 111.685 93.018  208.843 1.00 82.40  ? 501 NAP A C8A 1 
HETATM 5487 N N7A . NAP C 2 .   ? 110.605 92.688  208.094 1.00 80.26  ? 501 NAP A N7A 1 
HETATM 5488 C C5A . NAP C 2 .   ? 111.055 92.309  206.890 1.00 85.08  ? 501 NAP A C5A 1 
HETATM 5489 C C6A . NAP C 2 .   ? 110.453 91.838  205.626 1.00 86.87  ? 501 NAP A C6A 1 
HETATM 5490 N N6A . NAP C 2 .   ? 109.117 91.701  205.498 1.00 78.64  ? 501 NAP A N6A 1 
HETATM 5491 N N1A . NAP C 2 .   ? 111.278 91.550  204.602 1.00 88.44  ? 501 NAP A N1A 1 
HETATM 5492 C C2A . NAP C 2 .   ? 112.610 91.682  204.714 1.00 89.97  ? 501 NAP A C2A 1 
HETATM 5493 N N3A . NAP C 2 .   ? 113.227 92.101  205.830 1.00 92.67  ? 501 NAP A N3A 1 
HETATM 5494 C C4A . NAP C 2 .   ? 112.514 92.426  206.930 1.00 90.54  ? 501 NAP A C4A 1 
HETATM 5495 O O3  . NAP C 2 .   ? 116.579 90.135  214.290 1.00 100.00 ? 501 NAP A O3  1 
HETATM 5496 P PN  . NAP C 2 .   ? 118.072 89.550  214.391 1.00 107.80 ? 501 NAP A PN  1 
HETATM 5497 O O1N . NAP C 2 .   ? 118.701 90.092  215.647 1.00 89.58  ? 501 NAP A O1N 1 
HETATM 5498 O O2N . NAP C 2 .   ? 118.793 89.653  213.072 1.00 76.88  ? 501 NAP A O2N 1 
HETATM 5499 O O5D . NAP C 2 .   ? 117.738 87.999  214.627 1.00 95.54  ? 501 NAP A O5D 1 
HETATM 5500 C C5D . NAP C 2 .   ? 117.292 87.203  213.535 1.00 80.47  ? 501 NAP A C5D 1 
HETATM 5501 C C4D . NAP C 2 .   ? 115.929 86.590  213.825 1.00 75.67  ? 501 NAP A C4D 1 
HETATM 5502 O O4D . NAP C 2 .   ? 116.093 85.254  214.293 1.00 77.43  ? 501 NAP A O4D 1 
HETATM 5503 C C3D . NAP C 2 .   ? 115.174 87.350  214.895 1.00 76.14  ? 501 NAP A C3D 1 
HETATM 5504 O O3D . NAP C 2 .   ? 113.985 87.899  214.334 1.00 76.09  ? 501 NAP A O3D 1 
HETATM 5505 C C2D . NAP C 2 .   ? 114.851 86.349  215.977 1.00 72.18  ? 501 NAP A C2D 1 
HETATM 5506 O O2D . NAP C 2 .   ? 113.457 86.371  216.277 1.00 68.12  ? 501 NAP A O2D 1 
HETATM 5507 C C1D . NAP C 2 .   ? 115.263 84.999  215.423 1.00 72.17  ? 501 NAP A C1D 1 
HETATM 5508 N N1N . NAP C 2 .   ? 116.021 84.230  216.407 1.00 71.51  ? 501 NAP A N1N 1 
HETATM 5509 C C2N . NAP C 2 .   ? 116.180 82.914  216.239 1.00 66.25  ? 501 NAP A C2N 1 
HETATM 5510 C C3N . NAP C 2 .   ? 116.899 82.165  217.161 1.00 71.97  ? 501 NAP A C3N 1 
HETATM 5511 C C7N . NAP C 2 .   ? 117.082 80.689  216.978 1.00 69.37  ? 501 NAP A C7N 1 
HETATM 5512 O O7N . NAP C 2 .   ? 117.584 80.036  217.876 1.00 71.06  ? 501 NAP A O7N 1 
HETATM 5513 N N7N . NAP C 2 .   ? 116.697 80.128  215.835 1.00 63.05  ? 501 NAP A N7N 1 
HETATM 5514 C C4N . NAP C 2 .   ? 117.458 82.791  218.261 1.00 72.21  ? 501 NAP A C4N 1 
HETATM 5515 C C5N . NAP C 2 .   ? 117.281 84.154  218.410 1.00 74.23  ? 501 NAP A C5N 1 
HETATM 5516 C C6N . NAP C 2 .   ? 116.553 84.854  217.459 1.00 78.14  ? 501 NAP A C6N 1 
HETATM 5517 P P2B . NAP C 2 .   ? 115.068 96.845  208.937 1.00 108.85 ? 501 NAP A P2B 1 
HETATM 5518 O O1X . NAP C 2 .   ? 113.596 97.062  208.706 1.00 89.28  ? 501 NAP A O1X 1 
HETATM 5519 O O2X . NAP C 2 .   ? 115.557 97.263  210.298 1.00 95.96  ? 501 NAP A O2X 1 
HETATM 5520 O O3X . NAP C 2 .   ? 115.950 97.296  207.804 1.00 99.08  ? 501 NAP A O3X 1 
HETATM 5521 P PA  . NAP D 2 .   ? 112.230 55.761  190.001 1.00 115.36 ? 501 NAP B PA  1 
HETATM 5522 O O1A . NAP D 2 .   ? 111.583 54.905  188.941 1.00 91.69  ? 501 NAP B O1A 1 
HETATM 5523 O O2A . NAP D 2 .   ? 112.241 55.333  191.444 1.00 106.90 ? 501 NAP B O2A 1 
HETATM 5524 O O5B . NAP D 2 .   ? 111.545 57.215  189.981 1.00 99.60  ? 501 NAP B O5B 1 
HETATM 5525 C C5B . NAP D 2 .   ? 110.125 57.366  190.019 1.00 101.00 ? 501 NAP B C5B 1 
HETATM 5526 C C4B . NAP D 2 .   ? 109.459 56.353  190.940 1.00 99.21  ? 501 NAP B C4B 1 
HETATM 5527 O O4B . NAP D 2 .   ? 108.517 57.010  191.786 1.00 97.57  ? 501 NAP B O4B 1 
HETATM 5528 C C3B . NAP D 2 .   ? 108.705 55.296  190.157 1.00 106.18 ? 501 NAP B C3B 1 
HETATM 5529 O O3B . NAP D 2 .   ? 109.241 54.004  190.446 1.00 104.21 ? 501 NAP B O3B 1 
HETATM 5530 C C2B . NAP D 2 .   ? 107.257 55.399  190.579 1.00 106.85 ? 501 NAP B C2B 1 
HETATM 5531 O O2B . NAP D 2 .   ? 106.765 54.166  191.087 1.00 112.95 ? 501 NAP B O2B 1 
HETATM 5532 C C1B . NAP D 2 .   ? 107.213 56.456  191.657 1.00 101.24 ? 501 NAP B C1B 1 
HETATM 5533 N N9A . NAP D 2 .   ? 106.286 57.510  191.219 1.00 99.58  ? 501 NAP B N9A 1 
HETATM 5534 C C8A . NAP D 2 .   ? 105.965 57.772  189.944 1.00 98.10  ? 501 NAP B C8A 1 
HETATM 5535 N N7A . NAP D 2 .   ? 105.087 58.800  189.867 1.00 98.95  ? 501 NAP B N7A 1 
HETATM 5536 C C5A . NAP D 2 .   ? 104.840 59.213  191.119 1.00 99.96  ? 501 NAP B C5A 1 
HETATM 5537 C C6A . NAP D 2 .   ? 104.008 60.258  191.747 1.00 95.38  ? 501 NAP B C6A 1 
HETATM 5538 N N6A . NAP D 2 .   ? 103.248 61.090  190.999 1.00 89.38  ? 501 NAP B N6A 1 
HETATM 5539 N N1A . NAP D 2 .   ? 104.033 60.352  193.091 1.00 102.47 ? 501 NAP B N1A 1 
HETATM 5540 C C2A . NAP D 2 .   ? 104.787 59.533  193.842 1.00 100.96 ? 501 NAP B C2A 1 
HETATM 5541 N N3A . NAP D 2 .   ? 105.565 58.562  193.340 1.00 99.12  ? 501 NAP B N3A 1 
HETATM 5542 C C4A . NAP D 2 .   ? 105.634 58.356  192.008 1.00 103.16 ? 501 NAP B C4A 1 
HETATM 5543 O O3  . NAP D 2 .   ? 113.737 56.056  189.516 1.00 112.69 ? 501 NAP B O3  1 
HETATM 5544 P PN  . NAP D 2 .   ? 115.076 55.499  190.227 1.00 116.24 ? 501 NAP B PN  1 
HETATM 5545 O O1N . NAP D 2 .   ? 115.948 54.867  189.173 1.00 83.50  ? 501 NAP B O1N 1 
HETATM 5546 O O2N . NAP D 2 .   ? 114.761 54.729  191.481 1.00 92.04  ? 501 NAP B O2N 1 
HETATM 5547 O O5D . NAP D 2 .   ? 115.763 56.878  190.677 1.00 103.64 ? 501 NAP B O5D 1 
HETATM 5548 C C5D . NAP D 2 .   ? 115.018 57.829  191.429 1.00 90.59  ? 501 NAP B C5D 1 
HETATM 5549 C C4D . NAP D 2 .   ? 114.965 59.156  190.686 1.00 88.32  ? 501 NAP B C4D 1 
HETATM 5550 O O4D . NAP D 2 .   ? 116.139 59.918  190.953 1.00 83.73  ? 501 NAP B O4D 1 
HETATM 5551 C C3D . NAP D 2 .   ? 114.898 58.969  189.184 1.00 84.73  ? 501 NAP B C3D 1 
HETATM 5552 O O3D . NAP D 2 .   ? 113.579 59.260  188.727 1.00 84.03  ? 501 NAP B O3D 1 
HETATM 5553 C C2D . NAP D 2 .   ? 115.921 59.920  188.601 1.00 80.01  ? 501 NAP B C2D 1 
HETATM 5554 O O2D . NAP D 2 .   ? 115.304 60.869  187.730 1.00 77.44  ? 501 NAP B O2D 1 
HETATM 5555 C C1D . NAP D 2 .   ? 116.553 60.622  189.786 1.00 76.42  ? 501 NAP B C1D 1 
HETATM 5556 N N1N . NAP D 2 .   ? 118.007 60.582  189.715 1.00 74.04  ? 501 NAP B N1N 1 
HETATM 5557 C C2N . NAP D 2 .   ? 118.717 61.571  190.262 1.00 71.39  ? 501 NAP B C2N 1 
HETATM 5558 C C3N . NAP D 2 .   ? 120.104 61.553  190.212 1.00 73.62  ? 501 NAP B C3N 1 
HETATM 5559 C C7N . NAP D 2 .   ? 120.905 62.663  190.821 1.00 70.21  ? 501 NAP B C7N 1 
HETATM 5560 O O7N . NAP D 2 .   ? 122.086 62.763  190.544 1.00 70.91  ? 501 NAP B O7N 1 
HETATM 5561 N N7N . NAP D 2 .   ? 120.306 63.514  191.649 1.00 65.15  ? 501 NAP B N7N 1 
HETATM 5562 C C4N . NAP D 2 .   ? 120.751 60.497  189.591 1.00 72.87  ? 501 NAP B C4N 1 
HETATM 5563 C C5N . NAP D 2 .   ? 119.989 59.482  189.035 1.00 76.92  ? 501 NAP B C5N 1 
HETATM 5564 C C6N . NAP D 2 .   ? 118.605 59.551  189.115 1.00 78.33  ? 501 NAP B C6N 1 
HETATM 5565 P P2B . NAP D 2 .   ? 105.231 53.747  190.861 1.00 116.71 ? 501 NAP B P2B 1 
HETATM 5566 O O1X . NAP D 2 .   ? 104.622 54.941  190.174 1.00 110.66 ? 501 NAP B O1X 1 
HETATM 5567 O O2X . NAP D 2 .   ? 105.317 52.520  189.994 1.00 113.16 ? 501 NAP B O2X 1 
HETATM 5568 O O3X . NAP D 2 .   ? 104.715 53.501  192.254 1.00 106.02 ? 501 NAP B O3X 1 
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