data_8JL2
# 
_entry.id   8JL2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8JL2         pdb_00008jl2 10.2210/pdb8jl2/pdb 
WWPDB D_1300038144 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8JL2 
_pdbx_database_status.recvd_initial_deposition_date   2023-06-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              scshin84@kist.re.kr 
_pdbx_contact_author.name_first         Sangchul 
_pdbx_contact_author.name_last          Shin 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0156-680X 
# 
_audit_author.name               'Shin, S.C.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0003-0156-680X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Crystal structure of the Green fluorescent protein SE_A277 variant at pH 9.5' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
_citation_author.citation_id        primary 
_citation_author.name               'Shin, S.C.' 
_citation_author.ordinal            1 
_citation_author.identifier_ORCID   0000-0003-0156-680X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Green fluorescent protein' 26958.420 4   ? F64L,Q80R,S147D,N149Q,V163A,S175G,S202F,Q204T,A206T ? ? 
2 water   nat water                       18.015    811 ? ?                                                   ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;MSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTL(CRO)VQCFSRYPDHM
KRHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNDHQVYIMADKQK
NGIKANFKIRHNIEDGGVQLADHYQQNTPIGDGPVLLPDNHYLFTTSTLSKDPNEKRDHMVLLEFVTAAGITHGMDELYK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKR
HDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNDHQVYIMADKQKNG
IKANFKIRHNIEDGGVQLADHYQQNTPIGDGPVLLPDNHYLFTTSTLSKDPNEKRDHMVLLEFVTAAGITHGMDELYK
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   LYS n 
1 4   GLY n 
1 5   GLU n 
1 6   GLU n 
1 7   LEU n 
1 8   PHE n 
1 9   THR n 
1 10  GLY n 
1 11  VAL n 
1 12  VAL n 
1 13  PRO n 
1 14  ILE n 
1 15  LEU n 
1 16  VAL n 
1 17  GLU n 
1 18  LEU n 
1 19  ASP n 
1 20  GLY n 
1 21  ASP n 
1 22  VAL n 
1 23  ASN n 
1 24  GLY n 
1 25  HIS n 
1 26  LYS n 
1 27  PHE n 
1 28  SER n 
1 29  VAL n 
1 30  SER n 
1 31  GLY n 
1 32  GLU n 
1 33  GLY n 
1 34  GLU n 
1 35  GLY n 
1 36  ASP n 
1 37  ALA n 
1 38  THR n 
1 39  TYR n 
1 40  GLY n 
1 41  LYS n 
1 42  LEU n 
1 43  THR n 
1 44  LEU n 
1 45  LYS n 
1 46  PHE n 
1 47  ILE n 
1 48  CYS n 
1 49  THR n 
1 50  THR n 
1 51  GLY n 
1 52  LYS n 
1 53  LEU n 
1 54  PRO n 
1 55  VAL n 
1 56  PRO n 
1 57  TRP n 
1 58  PRO n 
1 59  THR n 
1 60  LEU n 
1 61  VAL n 
1 62  THR n 
1 63  THR n 
1 64  LEU n 
1 65  CRO n 
1 66  VAL n 
1 67  GLN n 
1 68  CYS n 
1 69  PHE n 
1 70  SER n 
1 71  ARG n 
1 72  TYR n 
1 73  PRO n 
1 74  ASP n 
1 75  HIS n 
1 76  MET n 
1 77  LYS n 
1 78  ARG n 
1 79  HIS n 
1 80  ASP n 
1 81  PHE n 
1 82  PHE n 
1 83  LYS n 
1 84  SER n 
1 85  ALA n 
1 86  MET n 
1 87  PRO n 
1 88  GLU n 
1 89  GLY n 
1 90  TYR n 
1 91  VAL n 
1 92  GLN n 
1 93  GLU n 
1 94  ARG n 
1 95  THR n 
1 96  ILE n 
1 97  PHE n 
1 98  PHE n 
1 99  LYS n 
1 100 ASP n 
1 101 ASP n 
1 102 GLY n 
1 103 ASN n 
1 104 TYR n 
1 105 LYS n 
1 106 THR n 
1 107 ARG n 
1 108 ALA n 
1 109 GLU n 
1 110 VAL n 
1 111 LYS n 
1 112 PHE n 
1 113 GLU n 
1 114 GLY n 
1 115 ASP n 
1 116 THR n 
1 117 LEU n 
1 118 VAL n 
1 119 ASN n 
1 120 ARG n 
1 121 ILE n 
1 122 GLU n 
1 123 LEU n 
1 124 LYS n 
1 125 GLY n 
1 126 ILE n 
1 127 ASP n 
1 128 PHE n 
1 129 LYS n 
1 130 GLU n 
1 131 ASP n 
1 132 GLY n 
1 133 ASN n 
1 134 ILE n 
1 135 LEU n 
1 136 GLY n 
1 137 HIS n 
1 138 LYS n 
1 139 LEU n 
1 140 GLU n 
1 141 TYR n 
1 142 ASN n 
1 143 TYR n 
1 144 ASN n 
1 145 ASP n 
1 146 HIS n 
1 147 GLN n 
1 148 VAL n 
1 149 TYR n 
1 150 ILE n 
1 151 MET n 
1 152 ALA n 
1 153 ASP n 
1 154 LYS n 
1 155 GLN n 
1 156 LYS n 
1 157 ASN n 
1 158 GLY n 
1 159 ILE n 
1 160 LYS n 
1 161 ALA n 
1 162 ASN n 
1 163 PHE n 
1 164 LYS n 
1 165 ILE n 
1 166 ARG n 
1 167 HIS n 
1 168 ASN n 
1 169 ILE n 
1 170 GLU n 
1 171 ASP n 
1 172 GLY n 
1 173 GLY n 
1 174 VAL n 
1 175 GLN n 
1 176 LEU n 
1 177 ALA n 
1 178 ASP n 
1 179 HIS n 
1 180 TYR n 
1 181 GLN n 
1 182 GLN n 
1 183 ASN n 
1 184 THR n 
1 185 PRO n 
1 186 ILE n 
1 187 GLY n 
1 188 ASP n 
1 189 GLY n 
1 190 PRO n 
1 191 VAL n 
1 192 LEU n 
1 193 LEU n 
1 194 PRO n 
1 195 ASP n 
1 196 ASN n 
1 197 HIS n 
1 198 TYR n 
1 199 LEU n 
1 200 PHE n 
1 201 THR n 
1 202 THR n 
1 203 SER n 
1 204 THR n 
1 205 LEU n 
1 206 SER n 
1 207 LYS n 
1 208 ASP n 
1 209 PRO n 
1 210 ASN n 
1 211 GLU n 
1 212 LYS n 
1 213 ARG n 
1 214 ASP n 
1 215 HIS n 
1 216 MET n 
1 217 VAL n 
1 218 LEU n 
1 219 LEU n 
1 220 GLU n 
1 221 PHE n 
1 222 VAL n 
1 223 THR n 
1 224 ALA n 
1 225 ALA n 
1 226 GLY n 
1 227 ILE n 
1 228 THR n 
1 229 HIS n 
1 230 GLY n 
1 231 MET n 
1 232 ASP n 
1 233 GLU n 
1 234 LEU n 
1 235 TYR n 
1 236 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   236 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 GFP 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Aequorea victoria' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     6100 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ?                             'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE ?                             'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                             'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                             'C4 H7 N O4'     133.103 
CRO 'L-peptide linking' n 
'{2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid' 
'PEPTIDE DERIVED CHROMOPHORE' 'C15 H17 N3 O5'  319.313 
CYS 'L-peptide linking' y CYSTEINE ?                             'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                             'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                             'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE ?                             'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE ?                             'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER ?                             'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                             'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE ?                             'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE ?                             'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE ?                             'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                             'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE ?                             'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE ?                             'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE ?                             'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                             'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE ?                             'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE ?                             'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   SER 2   2   ?   ?   ?   A . n 
A 1 3   LYS 3   3   3   LYS LYS A . n 
A 1 4   GLY 4   4   4   GLY GLY A . n 
A 1 5   GLU 5   5   5   GLU GLU A . n 
A 1 6   GLU 6   6   6   GLU GLU A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   THR 9   9   9   THR THR A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  VAL 11  11  11  VAL VAL A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  PRO 13  13  13  PRO PRO A . n 
A 1 14  ILE 14  14  14  ILE ILE A . n 
A 1 15  LEU 15  15  15  LEU LEU A . n 
A 1 16  VAL 16  16  16  VAL VAL A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  ASP 19  19  19  ASP ASP A . n 
A 1 20  GLY 20  20  20  GLY GLY A . n 
A 1 21  ASP 21  21  21  ASP ASP A . n 
A 1 22  VAL 22  22  22  VAL VAL A . n 
A 1 23  ASN 23  23  23  ASN ASN A . n 
A 1 24  GLY 24  24  24  GLY GLY A . n 
A 1 25  HIS 25  25  25  HIS HIS A . n 
A 1 26  LYS 26  26  26  LYS LYS A . n 
A 1 27  PHE 27  27  27  PHE PHE A . n 
A 1 28  SER 28  28  28  SER SER A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  SER 30  30  30  SER SER A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  GLU 32  32  32  GLU GLU A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  GLU 34  34  34  GLU GLU A . n 
A 1 35  GLY 35  35  35  GLY GLY A . n 
A 1 36  ASP 36  36  36  ASP ASP A . n 
A 1 37  ALA 37  37  37  ALA ALA A . n 
A 1 38  THR 38  38  38  THR THR A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  LYS 41  41  41  LYS LYS A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  THR 43  43  43  THR THR A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  LYS 45  45  45  LYS LYS A . n 
A 1 46  PHE 46  46  46  PHE PHE A . n 
A 1 47  ILE 47  47  47  ILE ILE A . n 
A 1 48  CYS 48  48  48  CYS CYS A . n 
A 1 49  THR 49  49  49  THR THR A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  LYS 52  52  52  LYS LYS A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  TRP 57  57  57  TRP TRP A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  LEU 60  60  60  LEU LEU A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  THR 62  62  62  THR THR A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  CRO 65  66  66  CRO CRO A . n 
A 1 66  VAL 66  68  68  VAL VAL A . n 
A 1 67  GLN 67  69  69  GLN GLN A . n 
A 1 68  CYS 68  70  70  CYS CYS A . n 
A 1 69  PHE 69  71  71  PHE PHE A . n 
A 1 70  SER 70  72  72  SER SER A . n 
A 1 71  ARG 71  73  73  ARG ARG A . n 
A 1 72  TYR 72  74  74  TYR TYR A . n 
A 1 73  PRO 73  75  75  PRO PRO A . n 
A 1 74  ASP 74  76  76  ASP ASP A . n 
A 1 75  HIS 75  77  77  HIS HIS A . n 
A 1 76  MET 76  78  78  MET MET A . n 
A 1 77  LYS 77  79  79  LYS LYS A . n 
A 1 78  ARG 78  80  80  ARG ARG A . n 
A 1 79  HIS 79  81  81  HIS HIS A . n 
A 1 80  ASP 80  82  82  ASP ASP A . n 
A 1 81  PHE 81  83  83  PHE PHE A . n 
A 1 82  PHE 82  84  84  PHE PHE A . n 
A 1 83  LYS 83  85  85  LYS LYS A . n 
A 1 84  SER 84  86  86  SER SER A . n 
A 1 85  ALA 85  87  87  ALA ALA A . n 
A 1 86  MET 86  88  88  MET MET A . n 
A 1 87  PRO 87  89  89  PRO PRO A . n 
A 1 88  GLU 88  90  90  GLU GLU A . n 
A 1 89  GLY 89  91  91  GLY GLY A . n 
A 1 90  TYR 90  92  92  TYR TYR A . n 
A 1 91  VAL 91  93  93  VAL VAL A . n 
A 1 92  GLN 92  94  94  GLN GLN A . n 
A 1 93  GLU 93  95  95  GLU GLU A . n 
A 1 94  ARG 94  96  96  ARG ARG A . n 
A 1 95  THR 95  97  97  THR THR A . n 
A 1 96  ILE 96  98  98  ILE ILE A . n 
A 1 97  PHE 97  99  99  PHE PHE A . n 
A 1 98  PHE 98  100 100 PHE PHE A . n 
A 1 99  LYS 99  101 101 LYS LYS A . n 
A 1 100 ASP 100 102 102 ASP ASP A . n 
A 1 101 ASP 101 103 103 ASP ASP A . n 
A 1 102 GLY 102 104 104 GLY GLY A . n 
A 1 103 ASN 103 105 105 ASN ASN A . n 
A 1 104 TYR 104 106 106 TYR TYR A . n 
A 1 105 LYS 105 107 107 LYS LYS A . n 
A 1 106 THR 106 108 108 THR THR A . n 
A 1 107 ARG 107 109 109 ARG ARG A . n 
A 1 108 ALA 108 110 110 ALA ALA A . n 
A 1 109 GLU 109 111 111 GLU GLU A . n 
A 1 110 VAL 110 112 112 VAL VAL A . n 
A 1 111 LYS 111 113 113 LYS LYS A . n 
A 1 112 PHE 112 114 114 PHE PHE A . n 
A 1 113 GLU 113 115 115 GLU GLU A . n 
A 1 114 GLY 114 116 116 GLY GLY A . n 
A 1 115 ASP 115 117 117 ASP ASP A . n 
A 1 116 THR 116 118 118 THR THR A . n 
A 1 117 LEU 117 119 119 LEU LEU A . n 
A 1 118 VAL 118 120 120 VAL VAL A . n 
A 1 119 ASN 119 121 121 ASN ASN A . n 
A 1 120 ARG 120 122 122 ARG ARG A . n 
A 1 121 ILE 121 123 123 ILE ILE A . n 
A 1 122 GLU 122 124 124 GLU GLU A . n 
A 1 123 LEU 123 125 125 LEU LEU A . n 
A 1 124 LYS 124 126 126 LYS LYS A . n 
A 1 125 GLY 125 127 127 GLY GLY A . n 
A 1 126 ILE 126 128 128 ILE ILE A . n 
A 1 127 ASP 127 129 129 ASP ASP A . n 
A 1 128 PHE 128 130 130 PHE PHE A . n 
A 1 129 LYS 129 131 131 LYS LYS A . n 
A 1 130 GLU 130 132 132 GLU GLU A . n 
A 1 131 ASP 131 133 133 ASP ASP A . n 
A 1 132 GLY 132 134 134 GLY GLY A . n 
A 1 133 ASN 133 135 135 ASN ASN A . n 
A 1 134 ILE 134 136 136 ILE ILE A . n 
A 1 135 LEU 135 137 137 LEU LEU A . n 
A 1 136 GLY 136 138 138 GLY GLY A . n 
A 1 137 HIS 137 139 139 HIS HIS A . n 
A 1 138 LYS 138 140 140 LYS LYS A . n 
A 1 139 LEU 139 141 141 LEU LEU A . n 
A 1 140 GLU 140 142 142 GLU GLU A . n 
A 1 141 TYR 141 143 143 TYR TYR A . n 
A 1 142 ASN 142 144 144 ASN ASN A . n 
A 1 143 TYR 143 145 145 TYR TYR A . n 
A 1 144 ASN 144 146 146 ASN ASN A . n 
A 1 145 ASP 145 147 147 ASP ASP A . n 
A 1 146 HIS 146 148 148 HIS HIS A . n 
A 1 147 GLN 147 149 149 GLN GLN A . n 
A 1 148 VAL 148 150 150 VAL VAL A . n 
A 1 149 TYR 149 151 151 TYR TYR A . n 
A 1 150 ILE 150 152 152 ILE ILE A . n 
A 1 151 MET 151 153 153 MET MET A . n 
A 1 152 ALA 152 154 154 ALA ALA A . n 
A 1 153 ASP 153 155 155 ASP ASP A . n 
A 1 154 LYS 154 156 156 LYS LYS A . n 
A 1 155 GLN 155 157 157 GLN GLN A . n 
A 1 156 LYS 156 158 158 LYS LYS A . n 
A 1 157 ASN 157 159 159 ASN ASN A . n 
A 1 158 GLY 158 160 160 GLY GLY A . n 
A 1 159 ILE 159 161 161 ILE ILE A . n 
A 1 160 LYS 160 162 162 LYS LYS A . n 
A 1 161 ALA 161 163 163 ALA ALA A . n 
A 1 162 ASN 162 164 164 ASN ASN A . n 
A 1 163 PHE 163 165 165 PHE PHE A . n 
A 1 164 LYS 164 166 166 LYS LYS A . n 
A 1 165 ILE 165 167 167 ILE ILE A . n 
A 1 166 ARG 166 168 168 ARG ARG A . n 
A 1 167 HIS 167 169 169 HIS HIS A . n 
A 1 168 ASN 168 170 170 ASN ASN A . n 
A 1 169 ILE 169 171 171 ILE ILE A . n 
A 1 170 GLU 170 172 172 GLU GLU A . n 
A 1 171 ASP 171 173 173 ASP ASP A . n 
A 1 172 GLY 172 174 174 GLY GLY A . n 
A 1 173 GLY 173 175 175 GLY GLY A . n 
A 1 174 VAL 174 176 176 VAL VAL A . n 
A 1 175 GLN 175 177 177 GLN GLN A . n 
A 1 176 LEU 176 178 178 LEU LEU A . n 
A 1 177 ALA 177 179 179 ALA ALA A . n 
A 1 178 ASP 178 180 180 ASP ASP A . n 
A 1 179 HIS 179 181 181 HIS HIS A . n 
A 1 180 TYR 180 182 182 TYR TYR A . n 
A 1 181 GLN 181 183 183 GLN GLN A . n 
A 1 182 GLN 182 184 184 GLN GLN A . n 
A 1 183 ASN 183 185 185 ASN ASN A . n 
A 1 184 THR 184 186 186 THR THR A . n 
A 1 185 PRO 185 187 187 PRO PRO A . n 
A 1 186 ILE 186 188 188 ILE ILE A . n 
A 1 187 GLY 187 189 189 GLY GLY A . n 
A 1 188 ASP 188 190 190 ASP ASP A . n 
A 1 189 GLY 189 191 191 GLY GLY A . n 
A 1 190 PRO 190 192 192 PRO PRO A . n 
A 1 191 VAL 191 193 193 VAL VAL A . n 
A 1 192 LEU 192 194 194 LEU LEU A . n 
A 1 193 LEU 193 195 195 LEU LEU A . n 
A 1 194 PRO 194 196 196 PRO PRO A . n 
A 1 195 ASP 195 197 197 ASP ASP A . n 
A 1 196 ASN 196 198 198 ASN ASN A . n 
A 1 197 HIS 197 199 199 HIS HIS A . n 
A 1 198 TYR 198 200 200 TYR TYR A . n 
A 1 199 LEU 199 201 201 LEU LEU A . n 
A 1 200 PHE 200 202 202 PHE PHE A . n 
A 1 201 THR 201 203 203 THR THR A . n 
A 1 202 THR 202 204 204 THR THR A . n 
A 1 203 SER 203 205 205 SER SER A . n 
A 1 204 THR 204 206 206 THR THR A . n 
A 1 205 LEU 205 207 207 LEU LEU A . n 
A 1 206 SER 206 208 208 SER SER A . n 
A 1 207 LYS 207 209 209 LYS LYS A . n 
A 1 208 ASP 208 210 210 ASP ASP A . n 
A 1 209 PRO 209 211 211 PRO PRO A . n 
A 1 210 ASN 210 212 212 ASN ASN A . n 
A 1 211 GLU 211 213 213 GLU GLU A . n 
A 1 212 LYS 212 214 214 LYS LYS A . n 
A 1 213 ARG 213 215 215 ARG ARG A . n 
A 1 214 ASP 214 216 216 ASP ASP A . n 
A 1 215 HIS 215 217 217 HIS HIS A . n 
A 1 216 MET 216 218 218 MET MET A . n 
A 1 217 VAL 217 219 219 VAL VAL A . n 
A 1 218 LEU 218 220 220 LEU LEU A . n 
A 1 219 LEU 219 221 221 LEU LEU A . n 
A 1 220 GLU 220 222 222 GLU GLU A . n 
A 1 221 PHE 221 223 223 PHE PHE A . n 
A 1 222 VAL 222 224 224 VAL VAL A . n 
A 1 223 THR 223 225 225 THR THR A . n 
A 1 224 ALA 224 226 226 ALA ALA A . n 
A 1 225 ALA 225 227 227 ALA ALA A . n 
A 1 226 GLY 226 228 228 GLY GLY A . n 
A 1 227 ILE 227 229 229 ILE ILE A . n 
A 1 228 THR 228 230 ?   ?   ?   A . n 
A 1 229 HIS 229 231 ?   ?   ?   A . n 
A 1 230 GLY 230 232 ?   ?   ?   A . n 
A 1 231 MET 231 233 ?   ?   ?   A . n 
A 1 232 ASP 232 234 ?   ?   ?   A . n 
A 1 233 GLU 233 235 ?   ?   ?   A . n 
A 1 234 LEU 234 236 ?   ?   ?   A . n 
A 1 235 TYR 235 237 ?   ?   ?   A . n 
A 1 236 LYS 236 238 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   SER 2   2   ?   ?   ?   B . n 
B 1 3   LYS 3   3   3   LYS LYS B . n 
B 1 4   GLY 4   4   4   GLY GLY B . n 
B 1 5   GLU 5   5   5   GLU GLU B . n 
B 1 6   GLU 6   6   6   GLU GLU B . n 
B 1 7   LEU 7   7   7   LEU LEU B . n 
B 1 8   PHE 8   8   8   PHE PHE B . n 
B 1 9   THR 9   9   9   THR THR B . n 
B 1 10  GLY 10  10  10  GLY GLY B . n 
B 1 11  VAL 11  11  11  VAL VAL B . n 
B 1 12  VAL 12  12  12  VAL VAL B . n 
B 1 13  PRO 13  13  13  PRO PRO B . n 
B 1 14  ILE 14  14  14  ILE ILE B . n 
B 1 15  LEU 15  15  15  LEU LEU B . n 
B 1 16  VAL 16  16  16  VAL VAL B . n 
B 1 17  GLU 17  17  17  GLU GLU B . n 
B 1 18  LEU 18  18  18  LEU LEU B . n 
B 1 19  ASP 19  19  19  ASP ASP B . n 
B 1 20  GLY 20  20  20  GLY GLY B . n 
B 1 21  ASP 21  21  21  ASP ASP B . n 
B 1 22  VAL 22  22  22  VAL VAL B . n 
B 1 23  ASN 23  23  23  ASN ASN B . n 
B 1 24  GLY 24  24  24  GLY GLY B . n 
B 1 25  HIS 25  25  25  HIS HIS B . n 
B 1 26  LYS 26  26  26  LYS LYS B . n 
B 1 27  PHE 27  27  27  PHE PHE B . n 
B 1 28  SER 28  28  28  SER SER B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  SER 30  30  30  SER SER B . n 
B 1 31  GLY 31  31  31  GLY GLY B . n 
B 1 32  GLU 32  32  32  GLU GLU B . n 
B 1 33  GLY 33  33  33  GLY GLY B . n 
B 1 34  GLU 34  34  34  GLU GLU B . n 
B 1 35  GLY 35  35  35  GLY GLY B . n 
B 1 36  ASP 36  36  36  ASP ASP B . n 
B 1 37  ALA 37  37  37  ALA ALA B . n 
B 1 38  THR 38  38  38  THR THR B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  GLY 40  40  40  GLY GLY B . n 
B 1 41  LYS 41  41  41  LYS LYS B . n 
B 1 42  LEU 42  42  42  LEU LEU B . n 
B 1 43  THR 43  43  43  THR THR B . n 
B 1 44  LEU 44  44  44  LEU LEU B . n 
B 1 45  LYS 45  45  45  LYS LYS B . n 
B 1 46  PHE 46  46  46  PHE PHE B . n 
B 1 47  ILE 47  47  47  ILE ILE B . n 
B 1 48  CYS 48  48  48  CYS CYS B . n 
B 1 49  THR 49  49  49  THR THR B . n 
B 1 50  THR 50  50  50  THR THR B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  LYS 52  52  52  LYS LYS B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  PRO 54  54  54  PRO PRO B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  PRO 56  56  56  PRO PRO B . n 
B 1 57  TRP 57  57  57  TRP TRP B . n 
B 1 58  PRO 58  58  58  PRO PRO B . n 
B 1 59  THR 59  59  59  THR THR B . n 
B 1 60  LEU 60  60  60  LEU LEU B . n 
B 1 61  VAL 61  61  61  VAL VAL B . n 
B 1 62  THR 62  62  62  THR THR B . n 
B 1 63  THR 63  63  63  THR THR B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  CRO 65  66  66  CRO CRO B . n 
B 1 66  VAL 66  68  68  VAL VAL B . n 
B 1 67  GLN 67  69  69  GLN GLN B . n 
B 1 68  CYS 68  70  70  CYS CYS B . n 
B 1 69  PHE 69  71  71  PHE PHE B . n 
B 1 70  SER 70  72  72  SER SER B . n 
B 1 71  ARG 71  73  73  ARG ARG B . n 
B 1 72  TYR 72  74  74  TYR TYR B . n 
B 1 73  PRO 73  75  75  PRO PRO B . n 
B 1 74  ASP 74  76  76  ASP ASP B . n 
B 1 75  HIS 75  77  77  HIS HIS B . n 
B 1 76  MET 76  78  78  MET MET B . n 
B 1 77  LYS 77  79  79  LYS LYS B . n 
B 1 78  ARG 78  80  80  ARG ARG B . n 
B 1 79  HIS 79  81  81  HIS HIS B . n 
B 1 80  ASP 80  82  82  ASP ASP B . n 
B 1 81  PHE 81  83  83  PHE PHE B . n 
B 1 82  PHE 82  84  84  PHE PHE B . n 
B 1 83  LYS 83  85  85  LYS LYS B . n 
B 1 84  SER 84  86  86  SER SER B . n 
B 1 85  ALA 85  87  87  ALA ALA B . n 
B 1 86  MET 86  88  88  MET MET B . n 
B 1 87  PRO 87  89  89  PRO PRO B . n 
B 1 88  GLU 88  90  90  GLU GLU B . n 
B 1 89  GLY 89  91  91  GLY GLY B . n 
B 1 90  TYR 90  92  92  TYR TYR B . n 
B 1 91  VAL 91  93  93  VAL VAL B . n 
B 1 92  GLN 92  94  94  GLN GLN B . n 
B 1 93  GLU 93  95  95  GLU GLU B . n 
B 1 94  ARG 94  96  96  ARG ARG B . n 
B 1 95  THR 95  97  97  THR THR B . n 
B 1 96  ILE 96  98  98  ILE ILE B . n 
B 1 97  PHE 97  99  99  PHE PHE B . n 
B 1 98  PHE 98  100 100 PHE PHE B . n 
B 1 99  LYS 99  101 101 LYS LYS B . n 
B 1 100 ASP 100 102 102 ASP ASP B . n 
B 1 101 ASP 101 103 103 ASP ASP B . n 
B 1 102 GLY 102 104 104 GLY GLY B . n 
B 1 103 ASN 103 105 105 ASN ASN B . n 
B 1 104 TYR 104 106 106 TYR TYR B . n 
B 1 105 LYS 105 107 107 LYS LYS B . n 
B 1 106 THR 106 108 108 THR THR B . n 
B 1 107 ARG 107 109 109 ARG ARG B . n 
B 1 108 ALA 108 110 110 ALA ALA B . n 
B 1 109 GLU 109 111 111 GLU GLU B . n 
B 1 110 VAL 110 112 112 VAL VAL B . n 
B 1 111 LYS 111 113 113 LYS LYS B . n 
B 1 112 PHE 112 114 114 PHE PHE B . n 
B 1 113 GLU 113 115 115 GLU GLU B . n 
B 1 114 GLY 114 116 116 GLY GLY B . n 
B 1 115 ASP 115 117 117 ASP ASP B . n 
B 1 116 THR 116 118 118 THR THR B . n 
B 1 117 LEU 117 119 119 LEU LEU B . n 
B 1 118 VAL 118 120 120 VAL VAL B . n 
B 1 119 ASN 119 121 121 ASN ASN B . n 
B 1 120 ARG 120 122 122 ARG ARG B . n 
B 1 121 ILE 121 123 123 ILE ILE B . n 
B 1 122 GLU 122 124 124 GLU GLU B . n 
B 1 123 LEU 123 125 125 LEU LEU B . n 
B 1 124 LYS 124 126 126 LYS LYS B . n 
B 1 125 GLY 125 127 127 GLY GLY B . n 
B 1 126 ILE 126 128 128 ILE ILE B . n 
B 1 127 ASP 127 129 129 ASP ASP B . n 
B 1 128 PHE 128 130 130 PHE PHE B . n 
B 1 129 LYS 129 131 131 LYS LYS B . n 
B 1 130 GLU 130 132 132 GLU GLU B . n 
B 1 131 ASP 131 133 133 ASP ASP B . n 
B 1 132 GLY 132 134 134 GLY GLY B . n 
B 1 133 ASN 133 135 135 ASN ASN B . n 
B 1 134 ILE 134 136 136 ILE ILE B . n 
B 1 135 LEU 135 137 137 LEU LEU B . n 
B 1 136 GLY 136 138 138 GLY GLY B . n 
B 1 137 HIS 137 139 139 HIS HIS B . n 
B 1 138 LYS 138 140 140 LYS LYS B . n 
B 1 139 LEU 139 141 141 LEU LEU B . n 
B 1 140 GLU 140 142 142 GLU GLU B . n 
B 1 141 TYR 141 143 143 TYR TYR B . n 
B 1 142 ASN 142 144 144 ASN ASN B . n 
B 1 143 TYR 143 145 145 TYR TYR B . n 
B 1 144 ASN 144 146 146 ASN ASN B . n 
B 1 145 ASP 145 147 147 ASP ASP B . n 
B 1 146 HIS 146 148 148 HIS HIS B . n 
B 1 147 GLN 147 149 149 GLN GLN B . n 
B 1 148 VAL 148 150 150 VAL VAL B . n 
B 1 149 TYR 149 151 151 TYR TYR B . n 
B 1 150 ILE 150 152 152 ILE ILE B . n 
B 1 151 MET 151 153 153 MET MET B . n 
B 1 152 ALA 152 154 154 ALA ALA B . n 
B 1 153 ASP 153 155 155 ASP ASP B . n 
B 1 154 LYS 154 156 156 LYS LYS B . n 
B 1 155 GLN 155 157 157 GLN GLN B . n 
B 1 156 LYS 156 158 158 LYS LYS B . n 
B 1 157 ASN 157 159 159 ASN ASN B . n 
B 1 158 GLY 158 160 160 GLY GLY B . n 
B 1 159 ILE 159 161 161 ILE ILE B . n 
B 1 160 LYS 160 162 162 LYS LYS B . n 
B 1 161 ALA 161 163 163 ALA ALA B . n 
B 1 162 ASN 162 164 164 ASN ASN B . n 
B 1 163 PHE 163 165 165 PHE PHE B . n 
B 1 164 LYS 164 166 166 LYS LYS B . n 
B 1 165 ILE 165 167 167 ILE ILE B . n 
B 1 166 ARG 166 168 168 ARG ARG B . n 
B 1 167 HIS 167 169 169 HIS HIS B . n 
B 1 168 ASN 168 170 170 ASN ASN B . n 
B 1 169 ILE 169 171 171 ILE ILE B . n 
B 1 170 GLU 170 172 172 GLU GLU B . n 
B 1 171 ASP 171 173 173 ASP ASP B . n 
B 1 172 GLY 172 174 174 GLY GLY B . n 
B 1 173 GLY 173 175 175 GLY GLY B . n 
B 1 174 VAL 174 176 176 VAL VAL B . n 
B 1 175 GLN 175 177 177 GLN GLN B . n 
B 1 176 LEU 176 178 178 LEU LEU B . n 
B 1 177 ALA 177 179 179 ALA ALA B . n 
B 1 178 ASP 178 180 180 ASP ASP B . n 
B 1 179 HIS 179 181 181 HIS HIS B . n 
B 1 180 TYR 180 182 182 TYR TYR B . n 
B 1 181 GLN 181 183 183 GLN GLN B . n 
B 1 182 GLN 182 184 184 GLN GLN B . n 
B 1 183 ASN 183 185 185 ASN ASN B . n 
B 1 184 THR 184 186 186 THR THR B . n 
B 1 185 PRO 185 187 187 PRO PRO B . n 
B 1 186 ILE 186 188 188 ILE ILE B . n 
B 1 187 GLY 187 189 189 GLY GLY B . n 
B 1 188 ASP 188 190 190 ASP ASP B . n 
B 1 189 GLY 189 191 191 GLY GLY B . n 
B 1 190 PRO 190 192 192 PRO PRO B . n 
B 1 191 VAL 191 193 193 VAL VAL B . n 
B 1 192 LEU 192 194 194 LEU LEU B . n 
B 1 193 LEU 193 195 195 LEU LEU B . n 
B 1 194 PRO 194 196 196 PRO PRO B . n 
B 1 195 ASP 195 197 197 ASP ASP B . n 
B 1 196 ASN 196 198 198 ASN ASN B . n 
B 1 197 HIS 197 199 199 HIS HIS B . n 
B 1 198 TYR 198 200 200 TYR TYR B . n 
B 1 199 LEU 199 201 201 LEU LEU B . n 
B 1 200 PHE 200 202 202 PHE PHE B . n 
B 1 201 THR 201 203 203 THR THR B . n 
B 1 202 THR 202 204 204 THR THR B . n 
B 1 203 SER 203 205 205 SER SER B . n 
B 1 204 THR 204 206 206 THR THR B . n 
B 1 205 LEU 205 207 207 LEU LEU B . n 
B 1 206 SER 206 208 208 SER SER B . n 
B 1 207 LYS 207 209 209 LYS LYS B . n 
B 1 208 ASP 208 210 210 ASP ASP B . n 
B 1 209 PRO 209 211 211 PRO PRO B . n 
B 1 210 ASN 210 212 212 ASN ASN B . n 
B 1 211 GLU 211 213 213 GLU GLU B . n 
B 1 212 LYS 212 214 214 LYS LYS B . n 
B 1 213 ARG 213 215 215 ARG ARG B . n 
B 1 214 ASP 214 216 216 ASP ASP B . n 
B 1 215 HIS 215 217 217 HIS HIS B . n 
B 1 216 MET 216 218 218 MET MET B . n 
B 1 217 VAL 217 219 219 VAL VAL B . n 
B 1 218 LEU 218 220 220 LEU LEU B . n 
B 1 219 LEU 219 221 221 LEU LEU B . n 
B 1 220 GLU 220 222 222 GLU GLU B . n 
B 1 221 PHE 221 223 223 PHE PHE B . n 
B 1 222 VAL 222 224 224 VAL VAL B . n 
B 1 223 THR 223 225 225 THR THR B . n 
B 1 224 ALA 224 226 226 ALA ALA B . n 
B 1 225 ALA 225 227 227 ALA ALA B . n 
B 1 226 GLY 226 228 228 GLY GLY B . n 
B 1 227 ILE 227 229 229 ILE ILE B . n 
B 1 228 THR 228 230 ?   ?   ?   B . n 
B 1 229 HIS 229 231 ?   ?   ?   B . n 
B 1 230 GLY 230 232 ?   ?   ?   B . n 
B 1 231 MET 231 233 ?   ?   ?   B . n 
B 1 232 ASP 232 234 ?   ?   ?   B . n 
B 1 233 GLU 233 235 ?   ?   ?   B . n 
B 1 234 LEU 234 236 ?   ?   ?   B . n 
B 1 235 TYR 235 237 ?   ?   ?   B . n 
B 1 236 LYS 236 238 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   SER 2   2   ?   ?   ?   C . n 
C 1 3   LYS 3   3   3   LYS LYS C . n 
C 1 4   GLY 4   4   4   GLY GLY C . n 
C 1 5   GLU 5   5   5   GLU GLU C . n 
C 1 6   GLU 6   6   6   GLU GLU C . n 
C 1 7   LEU 7   7   7   LEU LEU C . n 
C 1 8   PHE 8   8   8   PHE PHE C . n 
C 1 9   THR 9   9   9   THR THR C . n 
C 1 10  GLY 10  10  10  GLY GLY C . n 
C 1 11  VAL 11  11  11  VAL VAL C . n 
C 1 12  VAL 12  12  12  VAL VAL C . n 
C 1 13  PRO 13  13  13  PRO PRO C . n 
C 1 14  ILE 14  14  14  ILE ILE C . n 
C 1 15  LEU 15  15  15  LEU LEU C . n 
C 1 16  VAL 16  16  16  VAL VAL C . n 
C 1 17  GLU 17  17  17  GLU GLU C . n 
C 1 18  LEU 18  18  18  LEU LEU C . n 
C 1 19  ASP 19  19  19  ASP ASP C . n 
C 1 20  GLY 20  20  20  GLY GLY C . n 
C 1 21  ASP 21  21  21  ASP ASP C . n 
C 1 22  VAL 22  22  22  VAL VAL C . n 
C 1 23  ASN 23  23  23  ASN ASN C . n 
C 1 24  GLY 24  24  24  GLY GLY C . n 
C 1 25  HIS 25  25  25  HIS HIS C . n 
C 1 26  LYS 26  26  26  LYS LYS C . n 
C 1 27  PHE 27  27  27  PHE PHE C . n 
C 1 28  SER 28  28  28  SER SER C . n 
C 1 29  VAL 29  29  29  VAL VAL C . n 
C 1 30  SER 30  30  30  SER SER C . n 
C 1 31  GLY 31  31  31  GLY GLY C . n 
C 1 32  GLU 32  32  32  GLU GLU C . n 
C 1 33  GLY 33  33  33  GLY GLY C . n 
C 1 34  GLU 34  34  34  GLU GLU C . n 
C 1 35  GLY 35  35  35  GLY GLY C . n 
C 1 36  ASP 36  36  36  ASP ASP C . n 
C 1 37  ALA 37  37  37  ALA ALA C . n 
C 1 38  THR 38  38  38  THR THR C . n 
C 1 39  TYR 39  39  39  TYR TYR C . n 
C 1 40  GLY 40  40  40  GLY GLY C . n 
C 1 41  LYS 41  41  41  LYS LYS C . n 
C 1 42  LEU 42  42  42  LEU LEU C . n 
C 1 43  THR 43  43  43  THR THR C . n 
C 1 44  LEU 44  44  44  LEU LEU C . n 
C 1 45  LYS 45  45  45  LYS LYS C . n 
C 1 46  PHE 46  46  46  PHE PHE C . n 
C 1 47  ILE 47  47  47  ILE ILE C . n 
C 1 48  CYS 48  48  48  CYS CYS C . n 
C 1 49  THR 49  49  49  THR THR C . n 
C 1 50  THR 50  50  50  THR THR C . n 
C 1 51  GLY 51  51  51  GLY GLY C . n 
C 1 52  LYS 52  52  52  LYS LYS C . n 
C 1 53  LEU 53  53  53  LEU LEU C . n 
C 1 54  PRO 54  54  54  PRO PRO C . n 
C 1 55  VAL 55  55  55  VAL VAL C . n 
C 1 56  PRO 56  56  56  PRO PRO C . n 
C 1 57  TRP 57  57  57  TRP TRP C . n 
C 1 58  PRO 58  58  58  PRO PRO C . n 
C 1 59  THR 59  59  59  THR THR C . n 
C 1 60  LEU 60  60  60  LEU LEU C . n 
C 1 61  VAL 61  61  61  VAL VAL C . n 
C 1 62  THR 62  62  62  THR THR C . n 
C 1 63  THR 63  63  63  THR THR C . n 
C 1 64  LEU 64  64  64  LEU LEU C . n 
C 1 65  CRO 65  66  66  CRO CRO C . n 
C 1 66  VAL 66  68  68  VAL VAL C . n 
C 1 67  GLN 67  69  69  GLN GLN C . n 
C 1 68  CYS 68  70  70  CYS CYS C . n 
C 1 69  PHE 69  71  71  PHE PHE C . n 
C 1 70  SER 70  72  72  SER SER C . n 
C 1 71  ARG 71  73  73  ARG ARG C . n 
C 1 72  TYR 72  74  74  TYR TYR C . n 
C 1 73  PRO 73  75  75  PRO PRO C . n 
C 1 74  ASP 74  76  76  ASP ASP C . n 
C 1 75  HIS 75  77  77  HIS HIS C . n 
C 1 76  MET 76  78  78  MET MET C . n 
C 1 77  LYS 77  79  79  LYS LYS C . n 
C 1 78  ARG 78  80  80  ARG ARG C . n 
C 1 79  HIS 79  81  81  HIS HIS C . n 
C 1 80  ASP 80  82  82  ASP ASP C . n 
C 1 81  PHE 81  83  83  PHE PHE C . n 
C 1 82  PHE 82  84  84  PHE PHE C . n 
C 1 83  LYS 83  85  85  LYS LYS C . n 
C 1 84  SER 84  86  86  SER SER C . n 
C 1 85  ALA 85  87  87  ALA ALA C . n 
C 1 86  MET 86  88  88  MET MET C . n 
C 1 87  PRO 87  89  89  PRO PRO C . n 
C 1 88  GLU 88  90  90  GLU GLU C . n 
C 1 89  GLY 89  91  91  GLY GLY C . n 
C 1 90  TYR 90  92  92  TYR TYR C . n 
C 1 91  VAL 91  93  93  VAL VAL C . n 
C 1 92  GLN 92  94  94  GLN GLN C . n 
C 1 93  GLU 93  95  95  GLU GLU C . n 
C 1 94  ARG 94  96  96  ARG ARG C . n 
C 1 95  THR 95  97  97  THR THR C . n 
C 1 96  ILE 96  98  98  ILE ILE C . n 
C 1 97  PHE 97  99  99  PHE PHE C . n 
C 1 98  PHE 98  100 100 PHE PHE C . n 
C 1 99  LYS 99  101 101 LYS LYS C . n 
C 1 100 ASP 100 102 102 ASP ASP C . n 
C 1 101 ASP 101 103 103 ASP ASP C . n 
C 1 102 GLY 102 104 104 GLY GLY C . n 
C 1 103 ASN 103 105 105 ASN ASN C . n 
C 1 104 TYR 104 106 106 TYR TYR C . n 
C 1 105 LYS 105 107 107 LYS LYS C . n 
C 1 106 THR 106 108 108 THR THR C . n 
C 1 107 ARG 107 109 109 ARG ARG C . n 
C 1 108 ALA 108 110 110 ALA ALA C . n 
C 1 109 GLU 109 111 111 GLU GLU C . n 
C 1 110 VAL 110 112 112 VAL VAL C . n 
C 1 111 LYS 111 113 113 LYS LYS C . n 
C 1 112 PHE 112 114 114 PHE PHE C . n 
C 1 113 GLU 113 115 115 GLU GLU C . n 
C 1 114 GLY 114 116 116 GLY GLY C . n 
C 1 115 ASP 115 117 117 ASP ASP C . n 
C 1 116 THR 116 118 118 THR THR C . n 
C 1 117 LEU 117 119 119 LEU LEU C . n 
C 1 118 VAL 118 120 120 VAL VAL C . n 
C 1 119 ASN 119 121 121 ASN ASN C . n 
C 1 120 ARG 120 122 122 ARG ARG C . n 
C 1 121 ILE 121 123 123 ILE ILE C . n 
C 1 122 GLU 122 124 124 GLU GLU C . n 
C 1 123 LEU 123 125 125 LEU LEU C . n 
C 1 124 LYS 124 126 126 LYS LYS C . n 
C 1 125 GLY 125 127 127 GLY GLY C . n 
C 1 126 ILE 126 128 128 ILE ILE C . n 
C 1 127 ASP 127 129 129 ASP ASP C . n 
C 1 128 PHE 128 130 130 PHE PHE C . n 
C 1 129 LYS 129 131 131 LYS LYS C . n 
C 1 130 GLU 130 132 132 GLU GLU C . n 
C 1 131 ASP 131 133 133 ASP ASP C . n 
C 1 132 GLY 132 134 134 GLY GLY C . n 
C 1 133 ASN 133 135 135 ASN ASN C . n 
C 1 134 ILE 134 136 136 ILE ILE C . n 
C 1 135 LEU 135 137 137 LEU LEU C . n 
C 1 136 GLY 136 138 138 GLY GLY C . n 
C 1 137 HIS 137 139 139 HIS HIS C . n 
C 1 138 LYS 138 140 140 LYS LYS C . n 
C 1 139 LEU 139 141 141 LEU LEU C . n 
C 1 140 GLU 140 142 142 GLU GLU C . n 
C 1 141 TYR 141 143 143 TYR TYR C . n 
C 1 142 ASN 142 144 144 ASN ASN C . n 
C 1 143 TYR 143 145 145 TYR TYR C . n 
C 1 144 ASN 144 146 146 ASN ASN C . n 
C 1 145 ASP 145 147 147 ASP ASP C . n 
C 1 146 HIS 146 148 148 HIS HIS C . n 
C 1 147 GLN 147 149 149 GLN GLN C . n 
C 1 148 VAL 148 150 150 VAL VAL C . n 
C 1 149 TYR 149 151 151 TYR TYR C . n 
C 1 150 ILE 150 152 152 ILE ILE C . n 
C 1 151 MET 151 153 153 MET MET C . n 
C 1 152 ALA 152 154 154 ALA ALA C . n 
C 1 153 ASP 153 155 155 ASP ASP C . n 
C 1 154 LYS 154 156 156 LYS LYS C . n 
C 1 155 GLN 155 157 157 GLN GLN C . n 
C 1 156 LYS 156 158 158 LYS LYS C . n 
C 1 157 ASN 157 159 159 ASN ASN C . n 
C 1 158 GLY 158 160 160 GLY GLY C . n 
C 1 159 ILE 159 161 161 ILE ILE C . n 
C 1 160 LYS 160 162 162 LYS LYS C . n 
C 1 161 ALA 161 163 163 ALA ALA C . n 
C 1 162 ASN 162 164 164 ASN ASN C . n 
C 1 163 PHE 163 165 165 PHE PHE C . n 
C 1 164 LYS 164 166 166 LYS LYS C . n 
C 1 165 ILE 165 167 167 ILE ILE C . n 
C 1 166 ARG 166 168 168 ARG ARG C . n 
C 1 167 HIS 167 169 169 HIS HIS C . n 
C 1 168 ASN 168 170 170 ASN ASN C . n 
C 1 169 ILE 169 171 171 ILE ILE C . n 
C 1 170 GLU 170 172 172 GLU GLU C . n 
C 1 171 ASP 171 173 173 ASP ASP C . n 
C 1 172 GLY 172 174 174 GLY GLY C . n 
C 1 173 GLY 173 175 175 GLY GLY C . n 
C 1 174 VAL 174 176 176 VAL VAL C . n 
C 1 175 GLN 175 177 177 GLN GLN C . n 
C 1 176 LEU 176 178 178 LEU LEU C . n 
C 1 177 ALA 177 179 179 ALA ALA C . n 
C 1 178 ASP 178 180 180 ASP ASP C . n 
C 1 179 HIS 179 181 181 HIS HIS C . n 
C 1 180 TYR 180 182 182 TYR TYR C . n 
C 1 181 GLN 181 183 183 GLN GLN C . n 
C 1 182 GLN 182 184 184 GLN GLN C . n 
C 1 183 ASN 183 185 185 ASN ASN C . n 
C 1 184 THR 184 186 186 THR THR C . n 
C 1 185 PRO 185 187 187 PRO PRO C . n 
C 1 186 ILE 186 188 188 ILE ILE C . n 
C 1 187 GLY 187 189 189 GLY GLY C . n 
C 1 188 ASP 188 190 190 ASP ASP C . n 
C 1 189 GLY 189 191 191 GLY GLY C . n 
C 1 190 PRO 190 192 192 PRO PRO C . n 
C 1 191 VAL 191 193 193 VAL VAL C . n 
C 1 192 LEU 192 194 194 LEU LEU C . n 
C 1 193 LEU 193 195 195 LEU LEU C . n 
C 1 194 PRO 194 196 196 PRO PRO C . n 
C 1 195 ASP 195 197 197 ASP ASP C . n 
C 1 196 ASN 196 198 198 ASN ASN C . n 
C 1 197 HIS 197 199 199 HIS HIS C . n 
C 1 198 TYR 198 200 200 TYR TYR C . n 
C 1 199 LEU 199 201 201 LEU LEU C . n 
C 1 200 PHE 200 202 202 PHE PHE C . n 
C 1 201 THR 201 203 203 THR THR C . n 
C 1 202 THR 202 204 204 THR THR C . n 
C 1 203 SER 203 205 205 SER SER C . n 
C 1 204 THR 204 206 206 THR THR C . n 
C 1 205 LEU 205 207 207 LEU LEU C . n 
C 1 206 SER 206 208 208 SER SER C . n 
C 1 207 LYS 207 209 209 LYS LYS C . n 
C 1 208 ASP 208 210 210 ASP ASP C . n 
C 1 209 PRO 209 211 211 PRO PRO C . n 
C 1 210 ASN 210 212 212 ASN ASN C . n 
C 1 211 GLU 211 213 213 GLU GLU C . n 
C 1 212 LYS 212 214 214 LYS LYS C . n 
C 1 213 ARG 213 215 215 ARG ARG C . n 
C 1 214 ASP 214 216 216 ASP ASP C . n 
C 1 215 HIS 215 217 217 HIS HIS C . n 
C 1 216 MET 216 218 218 MET MET C . n 
C 1 217 VAL 217 219 219 VAL VAL C . n 
C 1 218 LEU 218 220 220 LEU LEU C . n 
C 1 219 LEU 219 221 221 LEU LEU C . n 
C 1 220 GLU 220 222 222 GLU GLU C . n 
C 1 221 PHE 221 223 223 PHE PHE C . n 
C 1 222 VAL 222 224 224 VAL VAL C . n 
C 1 223 THR 223 225 225 THR THR C . n 
C 1 224 ALA 224 226 226 ALA ALA C . n 
C 1 225 ALA 225 227 227 ALA ALA C . n 
C 1 226 GLY 226 228 228 GLY GLY C . n 
C 1 227 ILE 227 229 229 ILE ILE C . n 
C 1 228 THR 228 230 ?   ?   ?   C . n 
C 1 229 HIS 229 231 ?   ?   ?   C . n 
C 1 230 GLY 230 232 ?   ?   ?   C . n 
C 1 231 MET 231 233 ?   ?   ?   C . n 
C 1 232 ASP 232 234 ?   ?   ?   C . n 
C 1 233 GLU 233 235 ?   ?   ?   C . n 
C 1 234 LEU 234 236 ?   ?   ?   C . n 
C 1 235 TYR 235 237 ?   ?   ?   C . n 
C 1 236 LYS 236 238 ?   ?   ?   C . n 
D 1 1   MET 1   1   ?   ?   ?   D . n 
D 1 2   SER 2   2   ?   ?   ?   D . n 
D 1 3   LYS 3   3   3   LYS LYS D . n 
D 1 4   GLY 4   4   4   GLY GLY D . n 
D 1 5   GLU 5   5   5   GLU GLU D . n 
D 1 6   GLU 6   6   6   GLU GLU D . n 
D 1 7   LEU 7   7   7   LEU LEU D . n 
D 1 8   PHE 8   8   8   PHE PHE D . n 
D 1 9   THR 9   9   9   THR THR D . n 
D 1 10  GLY 10  10  10  GLY GLY D . n 
D 1 11  VAL 11  11  11  VAL VAL D . n 
D 1 12  VAL 12  12  12  VAL VAL D . n 
D 1 13  PRO 13  13  13  PRO PRO D . n 
D 1 14  ILE 14  14  14  ILE ILE D . n 
D 1 15  LEU 15  15  15  LEU LEU D . n 
D 1 16  VAL 16  16  16  VAL VAL D . n 
D 1 17  GLU 17  17  17  GLU GLU D . n 
D 1 18  LEU 18  18  18  LEU LEU D . n 
D 1 19  ASP 19  19  19  ASP ASP D . n 
D 1 20  GLY 20  20  20  GLY GLY D . n 
D 1 21  ASP 21  21  21  ASP ASP D . n 
D 1 22  VAL 22  22  22  VAL VAL D . n 
D 1 23  ASN 23  23  23  ASN ASN D . n 
D 1 24  GLY 24  24  24  GLY GLY D . n 
D 1 25  HIS 25  25  25  HIS HIS D . n 
D 1 26  LYS 26  26  26  LYS LYS D . n 
D 1 27  PHE 27  27  27  PHE PHE D . n 
D 1 28  SER 28  28  28  SER SER D . n 
D 1 29  VAL 29  29  29  VAL VAL D . n 
D 1 30  SER 30  30  30  SER SER D . n 
D 1 31  GLY 31  31  31  GLY GLY D . n 
D 1 32  GLU 32  32  32  GLU GLU D . n 
D 1 33  GLY 33  33  33  GLY GLY D . n 
D 1 34  GLU 34  34  34  GLU GLU D . n 
D 1 35  GLY 35  35  35  GLY GLY D . n 
D 1 36  ASP 36  36  36  ASP ASP D . n 
D 1 37  ALA 37  37  37  ALA ALA D . n 
D 1 38  THR 38  38  38  THR THR D . n 
D 1 39  TYR 39  39  39  TYR TYR D . n 
D 1 40  GLY 40  40  40  GLY GLY D . n 
D 1 41  LYS 41  41  41  LYS LYS D . n 
D 1 42  LEU 42  42  42  LEU LEU D . n 
D 1 43  THR 43  43  43  THR THR D . n 
D 1 44  LEU 44  44  44  LEU LEU D . n 
D 1 45  LYS 45  45  45  LYS LYS D . n 
D 1 46  PHE 46  46  46  PHE PHE D . n 
D 1 47  ILE 47  47  47  ILE ILE D . n 
D 1 48  CYS 48  48  48  CYS CYS D . n 
D 1 49  THR 49  49  49  THR THR D . n 
D 1 50  THR 50  50  50  THR THR D . n 
D 1 51  GLY 51  51  51  GLY GLY D . n 
D 1 52  LYS 52  52  52  LYS LYS D . n 
D 1 53  LEU 53  53  53  LEU LEU D . n 
D 1 54  PRO 54  54  54  PRO PRO D . n 
D 1 55  VAL 55  55  55  VAL VAL D . n 
D 1 56  PRO 56  56  56  PRO PRO D . n 
D 1 57  TRP 57  57  57  TRP TRP D . n 
D 1 58  PRO 58  58  58  PRO PRO D . n 
D 1 59  THR 59  59  59  THR THR D . n 
D 1 60  LEU 60  60  60  LEU LEU D . n 
D 1 61  VAL 61  61  61  VAL VAL D . n 
D 1 62  THR 62  62  62  THR THR D . n 
D 1 63  THR 63  63  63  THR THR D . n 
D 1 64  LEU 64  64  64  LEU LEU D . n 
D 1 65  CRO 65  66  66  CRO CRO D . n 
D 1 66  VAL 66  68  68  VAL VAL D . n 
D 1 67  GLN 67  69  69  GLN GLN D . n 
D 1 68  CYS 68  70  70  CYS CYS D . n 
D 1 69  PHE 69  71  71  PHE PHE D . n 
D 1 70  SER 70  72  72  SER SER D . n 
D 1 71  ARG 71  73  73  ARG ARG D . n 
D 1 72  TYR 72  74  74  TYR TYR D . n 
D 1 73  PRO 73  75  75  PRO PRO D . n 
D 1 74  ASP 74  76  76  ASP ASP D . n 
D 1 75  HIS 75  77  77  HIS HIS D . n 
D 1 76  MET 76  78  78  MET MET D . n 
D 1 77  LYS 77  79  79  LYS LYS D . n 
D 1 78  ARG 78  80  80  ARG ARG D . n 
D 1 79  HIS 79  81  81  HIS HIS D . n 
D 1 80  ASP 80  82  82  ASP ASP D . n 
D 1 81  PHE 81  83  83  PHE PHE D . n 
D 1 82  PHE 82  84  84  PHE PHE D . n 
D 1 83  LYS 83  85  85  LYS LYS D . n 
D 1 84  SER 84  86  86  SER SER D . n 
D 1 85  ALA 85  87  87  ALA ALA D . n 
D 1 86  MET 86  88  88  MET MET D . n 
D 1 87  PRO 87  89  89  PRO PRO D . n 
D 1 88  GLU 88  90  90  GLU GLU D . n 
D 1 89  GLY 89  91  91  GLY GLY D . n 
D 1 90  TYR 90  92  92  TYR TYR D . n 
D 1 91  VAL 91  93  93  VAL VAL D . n 
D 1 92  GLN 92  94  94  GLN GLN D . n 
D 1 93  GLU 93  95  95  GLU GLU D . n 
D 1 94  ARG 94  96  96  ARG ARG D . n 
D 1 95  THR 95  97  97  THR THR D . n 
D 1 96  ILE 96  98  98  ILE ILE D . n 
D 1 97  PHE 97  99  99  PHE PHE D . n 
D 1 98  PHE 98  100 100 PHE PHE D . n 
D 1 99  LYS 99  101 101 LYS LYS D . n 
D 1 100 ASP 100 102 102 ASP ASP D . n 
D 1 101 ASP 101 103 103 ASP ASP D . n 
D 1 102 GLY 102 104 104 GLY GLY D . n 
D 1 103 ASN 103 105 105 ASN ASN D . n 
D 1 104 TYR 104 106 106 TYR TYR D . n 
D 1 105 LYS 105 107 107 LYS LYS D . n 
D 1 106 THR 106 108 108 THR THR D . n 
D 1 107 ARG 107 109 109 ARG ARG D . n 
D 1 108 ALA 108 110 110 ALA ALA D . n 
D 1 109 GLU 109 111 111 GLU GLU D . n 
D 1 110 VAL 110 112 112 VAL VAL D . n 
D 1 111 LYS 111 113 113 LYS LYS D . n 
D 1 112 PHE 112 114 114 PHE PHE D . n 
D 1 113 GLU 113 115 115 GLU GLU D . n 
D 1 114 GLY 114 116 116 GLY GLY D . n 
D 1 115 ASP 115 117 117 ASP ASP D . n 
D 1 116 THR 116 118 118 THR THR D . n 
D 1 117 LEU 117 119 119 LEU LEU D . n 
D 1 118 VAL 118 120 120 VAL VAL D . n 
D 1 119 ASN 119 121 121 ASN ASN D . n 
D 1 120 ARG 120 122 122 ARG ARG D . n 
D 1 121 ILE 121 123 123 ILE ILE D . n 
D 1 122 GLU 122 124 124 GLU GLU D . n 
D 1 123 LEU 123 125 125 LEU LEU D . n 
D 1 124 LYS 124 126 126 LYS LYS D . n 
D 1 125 GLY 125 127 127 GLY GLY D . n 
D 1 126 ILE 126 128 128 ILE ILE D . n 
D 1 127 ASP 127 129 129 ASP ASP D . n 
D 1 128 PHE 128 130 130 PHE PHE D . n 
D 1 129 LYS 129 131 131 LYS LYS D . n 
D 1 130 GLU 130 132 132 GLU GLU D . n 
D 1 131 ASP 131 133 133 ASP ASP D . n 
D 1 132 GLY 132 134 134 GLY GLY D . n 
D 1 133 ASN 133 135 135 ASN ASN D . n 
D 1 134 ILE 134 136 136 ILE ILE D . n 
D 1 135 LEU 135 137 137 LEU LEU D . n 
D 1 136 GLY 136 138 138 GLY GLY D . n 
D 1 137 HIS 137 139 139 HIS HIS D . n 
D 1 138 LYS 138 140 140 LYS LYS D . n 
D 1 139 LEU 139 141 141 LEU LEU D . n 
D 1 140 GLU 140 142 142 GLU GLU D . n 
D 1 141 TYR 141 143 143 TYR TYR D . n 
D 1 142 ASN 142 144 144 ASN ASN D . n 
D 1 143 TYR 143 145 145 TYR TYR D . n 
D 1 144 ASN 144 146 146 ASN ASN D . n 
D 1 145 ASP 145 147 147 ASP ASP D . n 
D 1 146 HIS 146 148 148 HIS HIS D . n 
D 1 147 GLN 147 149 149 GLN GLN D . n 
D 1 148 VAL 148 150 150 VAL VAL D . n 
D 1 149 TYR 149 151 151 TYR TYR D . n 
D 1 150 ILE 150 152 152 ILE ILE D . n 
D 1 151 MET 151 153 153 MET MET D . n 
D 1 152 ALA 152 154 154 ALA ALA D . n 
D 1 153 ASP 153 155 155 ASP ASP D . n 
D 1 154 LYS 154 156 156 LYS LYS D . n 
D 1 155 GLN 155 157 157 GLN GLN D . n 
D 1 156 LYS 156 158 158 LYS LYS D . n 
D 1 157 ASN 157 159 159 ASN ASN D . n 
D 1 158 GLY 158 160 160 GLY GLY D . n 
D 1 159 ILE 159 161 161 ILE ILE D . n 
D 1 160 LYS 160 162 162 LYS LYS D . n 
D 1 161 ALA 161 163 163 ALA ALA D . n 
D 1 162 ASN 162 164 164 ASN ASN D . n 
D 1 163 PHE 163 165 165 PHE PHE D . n 
D 1 164 LYS 164 166 166 LYS LYS D . n 
D 1 165 ILE 165 167 167 ILE ILE D . n 
D 1 166 ARG 166 168 168 ARG ARG D . n 
D 1 167 HIS 167 169 169 HIS HIS D . n 
D 1 168 ASN 168 170 170 ASN ASN D . n 
D 1 169 ILE 169 171 171 ILE ILE D . n 
D 1 170 GLU 170 172 172 GLU GLU D . n 
D 1 171 ASP 171 173 173 ASP ASP D . n 
D 1 172 GLY 172 174 174 GLY GLY D . n 
D 1 173 GLY 173 175 175 GLY GLY D . n 
D 1 174 VAL 174 176 176 VAL VAL D . n 
D 1 175 GLN 175 177 177 GLN GLN D . n 
D 1 176 LEU 176 178 178 LEU LEU D . n 
D 1 177 ALA 177 179 179 ALA ALA D . n 
D 1 178 ASP 178 180 180 ASP ASP D . n 
D 1 179 HIS 179 181 181 HIS HIS D . n 
D 1 180 TYR 180 182 182 TYR TYR D . n 
D 1 181 GLN 181 183 183 GLN GLN D . n 
D 1 182 GLN 182 184 184 GLN GLN D . n 
D 1 183 ASN 183 185 185 ASN ASN D . n 
D 1 184 THR 184 186 186 THR THR D . n 
D 1 185 PRO 185 187 187 PRO PRO D . n 
D 1 186 ILE 186 188 188 ILE ILE D . n 
D 1 187 GLY 187 189 189 GLY GLY D . n 
D 1 188 ASP 188 190 190 ASP ASP D . n 
D 1 189 GLY 189 191 191 GLY GLY D . n 
D 1 190 PRO 190 192 192 PRO PRO D . n 
D 1 191 VAL 191 193 193 VAL VAL D . n 
D 1 192 LEU 192 194 194 LEU LEU D . n 
D 1 193 LEU 193 195 195 LEU LEU D . n 
D 1 194 PRO 194 196 196 PRO PRO D . n 
D 1 195 ASP 195 197 197 ASP ASP D . n 
D 1 196 ASN 196 198 198 ASN ASN D . n 
D 1 197 HIS 197 199 199 HIS HIS D . n 
D 1 198 TYR 198 200 200 TYR TYR D . n 
D 1 199 LEU 199 201 201 LEU LEU D . n 
D 1 200 PHE 200 202 202 PHE PHE D . n 
D 1 201 THR 201 203 203 THR THR D . n 
D 1 202 THR 202 204 204 THR THR D . n 
D 1 203 SER 203 205 205 SER SER D . n 
D 1 204 THR 204 206 206 THR THR D . n 
D 1 205 LEU 205 207 207 LEU LEU D . n 
D 1 206 SER 206 208 208 SER SER D . n 
D 1 207 LYS 207 209 209 LYS LYS D . n 
D 1 208 ASP 208 210 210 ASP ASP D . n 
D 1 209 PRO 209 211 211 PRO PRO D . n 
D 1 210 ASN 210 212 212 ASN ASN D . n 
D 1 211 GLU 211 213 213 GLU GLU D . n 
D 1 212 LYS 212 214 214 LYS LYS D . n 
D 1 213 ARG 213 215 215 ARG ARG D . n 
D 1 214 ASP 214 216 216 ASP ASP D . n 
D 1 215 HIS 215 217 217 HIS HIS D . n 
D 1 216 MET 216 218 218 MET MET D . n 
D 1 217 VAL 217 219 219 VAL VAL D . n 
D 1 218 LEU 218 220 220 LEU LEU D . n 
D 1 219 LEU 219 221 221 LEU LEU D . n 
D 1 220 GLU 220 222 222 GLU GLU D . n 
D 1 221 PHE 221 223 223 PHE PHE D . n 
D 1 222 VAL 222 224 224 VAL VAL D . n 
D 1 223 THR 223 225 225 THR THR D . n 
D 1 224 ALA 224 226 226 ALA ALA D . n 
D 1 225 ALA 225 227 227 ALA ALA D . n 
D 1 226 GLY 226 228 228 GLY GLY D . n 
D 1 227 ILE 227 229 229 ILE ILE D . n 
D 1 228 THR 228 230 ?   ?   ?   D . n 
D 1 229 HIS 229 231 ?   ?   ?   D . n 
D 1 230 GLY 230 232 ?   ?   ?   D . n 
D 1 231 MET 231 233 ?   ?   ?   D . n 
D 1 232 ASP 232 234 ?   ?   ?   D . n 
D 1 233 GLU 233 235 ?   ?   ?   D . n 
D 1 234 LEU 234 236 ?   ?   ?   D . n 
D 1 235 TYR 235 237 ?   ?   ?   D . n 
D 1 236 LYS 236 238 ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        CRO 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   CRO 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 HOH 1   601 601 HOH HOH A . 
E 2 HOH 2   602 781 HOH HOH A . 
E 2 HOH 3   603 535 HOH HOH A . 
E 2 HOH 4   604 261 HOH HOH A . 
E 2 HOH 5   605 377 HOH HOH A . 
E 2 HOH 6   606 691 HOH HOH A . 
E 2 HOH 7   607 236 HOH HOH A . 
E 2 HOH 8   608 327 HOH HOH A . 
E 2 HOH 9   609 227 HOH HOH A . 
E 2 HOH 10  610 217 HOH HOH A . 
E 2 HOH 11  611 608 HOH HOH A . 
E 2 HOH 12  612 536 HOH HOH A . 
E 2 HOH 13  613 324 HOH HOH A . 
E 2 HOH 14  614 345 HOH HOH A . 
E 2 HOH 15  615 571 HOH HOH A . 
E 2 HOH 16  616 4   HOH HOH A . 
E 2 HOH 17  617 43  HOH HOH A . 
E 2 HOH 18  618 149 HOH HOH A . 
E 2 HOH 19  619 117 HOH HOH A . 
E 2 HOH 20  620 292 HOH HOH A . 
E 2 HOH 21  621 188 HOH HOH A . 
E 2 HOH 22  622 522 HOH HOH A . 
E 2 HOH 23  623 304 HOH HOH A . 
E 2 HOH 24  624 531 HOH HOH A . 
E 2 HOH 25  625 565 HOH HOH A . 
E 2 HOH 26  626 219 HOH HOH A . 
E 2 HOH 27  627 16  HOH HOH A . 
E 2 HOH 28  628 488 HOH HOH A . 
E 2 HOH 29  629 127 HOH HOH A . 
E 2 HOH 30  630 436 HOH HOH A . 
E 2 HOH 31  631 151 HOH HOH A . 
E 2 HOH 32  632 673 HOH HOH A . 
E 2 HOH 33  633 331 HOH HOH A . 
E 2 HOH 34  634 237 HOH HOH A . 
E 2 HOH 35  635 147 HOH HOH A . 
E 2 HOH 36  636 146 HOH HOH A . 
E 2 HOH 37  637 523 HOH HOH A . 
E 2 HOH 38  638 460 HOH HOH A . 
E 2 HOH 39  639 814 HOH HOH A . 
E 2 HOH 40  640 142 HOH HOH A . 
E 2 HOH 41  641 105 HOH HOH A . 
E 2 HOH 42  642 502 HOH HOH A . 
E 2 HOH 43  643 165 HOH HOH A . 
E 2 HOH 44  644 123 HOH HOH A . 
E 2 HOH 45  645 81  HOH HOH A . 
E 2 HOH 46  646 46  HOH HOH A . 
E 2 HOH 47  647 335 HOH HOH A . 
E 2 HOH 48  648 37  HOH HOH A . 
E 2 HOH 49  649 654 HOH HOH A . 
E 2 HOH 50  650 366 HOH HOH A . 
E 2 HOH 51  651 216 HOH HOH A . 
E 2 HOH 52  652 403 HOH HOH A . 
E 2 HOH 53  653 25  HOH HOH A . 
E 2 HOH 54  654 476 HOH HOH A . 
E 2 HOH 55  655 268 HOH HOH A . 
E 2 HOH 56  656 668 HOH HOH A . 
E 2 HOH 57  657 721 HOH HOH A . 
E 2 HOH 58  658 357 HOH HOH A . 
E 2 HOH 59  659 118 HOH HOH A . 
E 2 HOH 60  660 705 HOH HOH A . 
E 2 HOH 61  661 538 HOH HOH A . 
E 2 HOH 62  662 176 HOH HOH A . 
E 2 HOH 63  663 437 HOH HOH A . 
E 2 HOH 64  664 553 HOH HOH A . 
E 2 HOH 65  665 799 HOH HOH A . 
E 2 HOH 66  666 179 HOH HOH A . 
E 2 HOH 67  667 291 HOH HOH A . 
E 2 HOH 68  668 325 HOH HOH A . 
E 2 HOH 69  669 263 HOH HOH A . 
E 2 HOH 70  670 529 HOH HOH A . 
E 2 HOH 71  671 290 HOH HOH A . 
E 2 HOH 72  672 362 HOH HOH A . 
E 2 HOH 73  673 474 HOH HOH A . 
E 2 HOH 74  674 388 HOH HOH A . 
E 2 HOH 75  675 86  HOH HOH A . 
E 2 HOH 76  676 358 HOH HOH A . 
E 2 HOH 77  677 683 HOH HOH A . 
E 2 HOH 78  678 175 HOH HOH A . 
E 2 HOH 79  679 589 HOH HOH A . 
E 2 HOH 80  680 415 HOH HOH A . 
E 2 HOH 81  681 643 HOH HOH A . 
E 2 HOH 82  682 103 HOH HOH A . 
E 2 HOH 83  683 98  HOH HOH A . 
E 2 HOH 84  684 69  HOH HOH A . 
E 2 HOH 85  685 242 HOH HOH A . 
E 2 HOH 86  686 51  HOH HOH A . 
E 2 HOH 87  687 307 HOH HOH A . 
E 2 HOH 88  688 154 HOH HOH A . 
E 2 HOH 89  689 254 HOH HOH A . 
E 2 HOH 90  690 484 HOH HOH A . 
E 2 HOH 91  691 247 HOH HOH A . 
E 2 HOH 92  692 289 HOH HOH A . 
E 2 HOH 93  693 494 HOH HOH A . 
E 2 HOH 94  694 419 HOH HOH A . 
E 2 HOH 95  695 627 HOH HOH A . 
E 2 HOH 96  696 107 HOH HOH A . 
E 2 HOH 97  697 185 HOH HOH A . 
E 2 HOH 98  698 432 HOH HOH A . 
E 2 HOH 99  699 583 HOH HOH A . 
E 2 HOH 100 700 24  HOH HOH A . 
E 2 HOH 101 701 244 HOH HOH A . 
E 2 HOH 102 702 498 HOH HOH A . 
E 2 HOH 103 703 486 HOH HOH A . 
E 2 HOH 104 704 729 HOH HOH A . 
E 2 HOH 105 705 220 HOH HOH A . 
E 2 HOH 106 706 297 HOH HOH A . 
E 2 HOH 107 707 731 HOH HOH A . 
E 2 HOH 108 708 89  HOH HOH A . 
E 2 HOH 109 709 309 HOH HOH A . 
E 2 HOH 110 710 446 HOH HOH A . 
E 2 HOH 111 711 229 HOH HOH A . 
E 2 HOH 112 712 250 HOH HOH A . 
E 2 HOH 113 713 741 HOH HOH A . 
E 2 HOH 114 714 75  HOH HOH A . 
E 2 HOH 115 715 769 HOH HOH A . 
E 2 HOH 116 716 306 HOH HOH A . 
E 2 HOH 117 717 322 HOH HOH A . 
E 2 HOH 118 718 680 HOH HOH A . 
E 2 HOH 119 719 798 HOH HOH A . 
E 2 HOH 120 720 813 HOH HOH A . 
E 2 HOH 121 721 667 HOH HOH A . 
E 2 HOH 122 722 38  HOH HOH A . 
E 2 HOH 123 723 719 HOH HOH A . 
E 2 HOH 124 724 232 HOH HOH A . 
E 2 HOH 125 725 555 HOH HOH A . 
E 2 HOH 126 726 694 HOH HOH A . 
E 2 HOH 127 727 59  HOH HOH A . 
E 2 HOH 128 728 270 HOH HOH A . 
E 2 HOH 129 729 487 HOH HOH A . 
E 2 HOH 130 730 442 HOH HOH A . 
E 2 HOH 131 731 757 HOH HOH A . 
E 2 HOH 132 732 259 HOH HOH A . 
E 2 HOH 133 733 365 HOH HOH A . 
E 2 HOH 134 734 704 HOH HOH A . 
E 2 HOH 135 735 108 HOH HOH A . 
E 2 HOH 136 736 521 HOH HOH A . 
E 2 HOH 137 737 363 HOH HOH A . 
E 2 HOH 138 738 221 HOH HOH A . 
E 2 HOH 139 739 527 HOH HOH A . 
E 2 HOH 140 740 655 HOH HOH A . 
E 2 HOH 141 741 57  HOH HOH A . 
E 2 HOH 142 742 397 HOH HOH A . 
E 2 HOH 143 743 618 HOH HOH A . 
E 2 HOH 144 744 651 HOH HOH A . 
E 2 HOH 145 745 422 HOH HOH A . 
E 2 HOH 146 746 420 HOH HOH A . 
E 2 HOH 147 747 104 HOH HOH A . 
E 2 HOH 148 748 228 HOH HOH A . 
E 2 HOH 149 749 2   HOH HOH A . 
E 2 HOH 150 750 492 HOH HOH A . 
E 2 HOH 151 751 695 HOH HOH A . 
E 2 HOH 152 752 504 HOH HOH A . 
E 2 HOH 153 753 563 HOH HOH A . 
E 2 HOH 154 754 603 HOH HOH A . 
E 2 HOH 155 755 515 HOH HOH A . 
E 2 HOH 156 756 262 HOH HOH A . 
E 2 HOH 157 757 574 HOH HOH A . 
E 2 HOH 158 758 684 HOH HOH A . 
E 2 HOH 159 759 469 HOH HOH A . 
E 2 HOH 160 760 551 HOH HOH A . 
E 2 HOH 161 761 452 HOH HOH A . 
E 2 HOH 162 762 688 HOH HOH A . 
E 2 HOH 163 763 561 HOH HOH A . 
E 2 HOH 164 764 728 HOH HOH A . 
E 2 HOH 165 765 511 HOH HOH A . 
E 2 HOH 166 766 748 HOH HOH A . 
E 2 HOH 167 767 251 HOH HOH A . 
E 2 HOH 168 768 293 HOH HOH A . 
E 2 HOH 169 769 477 HOH HOH A . 
E 2 HOH 170 770 795 HOH HOH A . 
E 2 HOH 171 771 310 HOH HOH A . 
E 2 HOH 172 772 475 HOH HOH A . 
E 2 HOH 173 773 308 HOH HOH A . 
E 2 HOH 174 774 778 HOH HOH A . 
E 2 HOH 175 775 399 HOH HOH A . 
E 2 HOH 176 776 763 HOH HOH A . 
E 2 HOH 177 777 796 HOH HOH A . 
E 2 HOH 178 778 738 HOH HOH A . 
E 2 HOH 179 779 806 HOH HOH A . 
E 2 HOH 180 780 585 HOH HOH A . 
E 2 HOH 181 781 234 HOH HOH A . 
E 2 HOH 182 782 539 HOH HOH A . 
E 2 HOH 183 783 687 HOH HOH A . 
E 2 HOH 184 784 480 HOH HOH A . 
E 2 HOH 185 785 628 HOH HOH A . 
E 2 HOH 186 786 564 HOH HOH A . 
E 2 HOH 187 787 696 HOH HOH A . 
E 2 HOH 188 788 604 HOH HOH A . 
E 2 HOH 189 789 652 HOH HOH A . 
E 2 HOH 190 790 196 HOH HOH A . 
E 2 HOH 191 791 408 HOH HOH A . 
E 2 HOH 192 792 503 HOH HOH A . 
E 2 HOH 193 793 402 HOH HOH A . 
E 2 HOH 194 794 775 HOH HOH A . 
E 2 HOH 195 795 812 HOH HOH A . 
E 2 HOH 196 796 739 HOH HOH A . 
F 2 HOH 1   301 597 HOH HOH B . 
F 2 HOH 2   302 621 HOH HOH B . 
F 2 HOH 3   303 707 HOH HOH B . 
F 2 HOH 4   304 569 HOH HOH B . 
F 2 HOH 5   305 97  HOH HOH B . 
F 2 HOH 6   306 256 HOH HOH B . 
F 2 HOH 7   307 458 HOH HOH B . 
F 2 HOH 8   308 612 HOH HOH B . 
F 2 HOH 9   309 273 HOH HOH B . 
F 2 HOH 10  310 332 HOH HOH B . 
F 2 HOH 11  311 348 HOH HOH B . 
F 2 HOH 12  312 605 HOH HOH B . 
F 2 HOH 13  313 193 HOH HOH B . 
F 2 HOH 14  314 715 HOH HOH B . 
F 2 HOH 15  315 30  HOH HOH B . 
F 2 HOH 16  316 328 HOH HOH B . 
F 2 HOH 17  317 542 HOH HOH B . 
F 2 HOH 18  318 286 HOH HOH B . 
F 2 HOH 19  319 36  HOH HOH B . 
F 2 HOH 20  320 525 HOH HOH B . 
F 2 HOH 21  321 470 HOH HOH B . 
F 2 HOH 22  322 566 HOH HOH B . 
F 2 HOH 23  323 206 HOH HOH B . 
F 2 HOH 24  324 225 HOH HOH B . 
F 2 HOH 25  325 404 HOH HOH B . 
F 2 HOH 26  326 54  HOH HOH B . 
F 2 HOH 27  327 171 HOH HOH B . 
F 2 HOH 28  328 128 HOH HOH B . 
F 2 HOH 29  329 681 HOH HOH B . 
F 2 HOH 30  330 558 HOH HOH B . 
F 2 HOH 31  331 6   HOH HOH B . 
F 2 HOH 32  332 412 HOH HOH B . 
F 2 HOH 33  333 77  HOH HOH B . 
F 2 HOH 34  334 586 HOH HOH B . 
F 2 HOH 35  335 658 HOH HOH B . 
F 2 HOH 36  336 31  HOH HOH B . 
F 2 HOH 37  337 445 HOH HOH B . 
F 2 HOH 38  338 584 HOH HOH B . 
F 2 HOH 39  339 321 HOH HOH B . 
F 2 HOH 40  340 599 HOH HOH B . 
F 2 HOH 41  341 61  HOH HOH B . 
F 2 HOH 42  342 139 HOH HOH B . 
F 2 HOH 43  343 772 HOH HOH B . 
F 2 HOH 44  344 130 HOH HOH B . 
F 2 HOH 45  345 391 HOH HOH B . 
F 2 HOH 46  346 42  HOH HOH B . 
F 2 HOH 47  347 400 HOH HOH B . 
F 2 HOH 48  348 12  HOH HOH B . 
F 2 HOH 49  349 347 HOH HOH B . 
F 2 HOH 50  350 15  HOH HOH B . 
F 2 HOH 51  351 235 HOH HOH B . 
F 2 HOH 52  352 395 HOH HOH B . 
F 2 HOH 53  353 749 HOH HOH B . 
F 2 HOH 54  354 552 HOH HOH B . 
F 2 HOH 55  355 610 HOH HOH B . 
F 2 HOH 56  356 144 HOH HOH B . 
F 2 HOH 57  357 255 HOH HOH B . 
F 2 HOH 58  358 677 HOH HOH B . 
F 2 HOH 59  359 62  HOH HOH B . 
F 2 HOH 60  360 751 HOH HOH B . 
F 2 HOH 61  361 218 HOH HOH B . 
F 2 HOH 62  362 305 HOH HOH B . 
F 2 HOH 63  363 718 HOH HOH B . 
F 2 HOH 64  364 201 HOH HOH B . 
F 2 HOH 65  365 76  HOH HOH B . 
F 2 HOH 66  366 596 HOH HOH B . 
F 2 HOH 67  367 662 HOH HOH B . 
F 2 HOH 68  368 411 HOH HOH B . 
F 2 HOH 69  369 20  HOH HOH B . 
F 2 HOH 70  370 243 HOH HOH B . 
F 2 HOH 71  371 70  HOH HOH B . 
F 2 HOH 72  372 473 HOH HOH B . 
F 2 HOH 73  373 742 HOH HOH B . 
F 2 HOH 74  374 141 HOH HOH B . 
F 2 HOH 75  375 114 HOH HOH B . 
F 2 HOH 76  376 45  HOH HOH B . 
F 2 HOH 77  377 495 HOH HOH B . 
F 2 HOH 78  378 32  HOH HOH B . 
F 2 HOH 79  379 230 HOH HOH B . 
F 2 HOH 80  380 115 HOH HOH B . 
F 2 HOH 81  381 260 HOH HOH B . 
F 2 HOH 82  382 29  HOH HOH B . 
F 2 HOH 83  383 72  HOH HOH B . 
F 2 HOH 84  384 157 HOH HOH B . 
F 2 HOH 85  385 17  HOH HOH B . 
F 2 HOH 86  386 298 HOH HOH B . 
F 2 HOH 87  387 91  HOH HOH B . 
F 2 HOH 88  388 791 HOH HOH B . 
F 2 HOH 89  389 279 HOH HOH B . 
F 2 HOH 90  390 493 HOH HOH B . 
F 2 HOH 91  391 346 HOH HOH B . 
F 2 HOH 92  392 92  HOH HOH B . 
F 2 HOH 93  393 616 HOH HOH B . 
F 2 HOH 94  394 467 HOH HOH B . 
F 2 HOH 95  395 543 HOH HOH B . 
F 2 HOH 96  396 170 HOH HOH B . 
F 2 HOH 97  397 192 HOH HOH B . 
F 2 HOH 98  398 79  HOH HOH B . 
F 2 HOH 99  399 783 HOH HOH B . 
F 2 HOH 100 400 295 HOH HOH B . 
F 2 HOH 101 401 375 HOH HOH B . 
F 2 HOH 102 402 177 HOH HOH B . 
F 2 HOH 103 403 99  HOH HOH B . 
F 2 HOH 104 404 133 HOH HOH B . 
F 2 HOH 105 405 222 HOH HOH B . 
F 2 HOH 106 406 82  HOH HOH B . 
F 2 HOH 107 407 518 HOH HOH B . 
F 2 HOH 108 408 485 HOH HOH B . 
F 2 HOH 109 409 11  HOH HOH B . 
F 2 HOH 110 410 472 HOH HOH B . 
F 2 HOH 111 411 113 HOH HOH B . 
F 2 HOH 112 412 294 HOH HOH B . 
F 2 HOH 113 413 639 HOH HOH B . 
F 2 HOH 114 414 635 HOH HOH B . 
F 2 HOH 115 415 161 HOH HOH B . 
F 2 HOH 116 416 797 HOH HOH B . 
F 2 HOH 117 417 779 HOH HOH B . 
F 2 HOH 118 418 180 HOH HOH B . 
F 2 HOH 119 419 276 HOH HOH B . 
F 2 HOH 120 420 258 HOH HOH B . 
F 2 HOH 121 421 313 HOH HOH B . 
F 2 HOH 122 422 456 HOH HOH B . 
F 2 HOH 123 423 168 HOH HOH B . 
F 2 HOH 124 424 126 HOH HOH B . 
F 2 HOH 125 425 125 HOH HOH B . 
F 2 HOH 126 426 93  HOH HOH B . 
F 2 HOH 127 427 509 HOH HOH B . 
F 2 HOH 128 428 771 HOH HOH B . 
F 2 HOH 129 429 393 HOH HOH B . 
F 2 HOH 130 430 203 HOH HOH B . 
F 2 HOH 131 431 427 HOH HOH B . 
F 2 HOH 132 432 271 HOH HOH B . 
F 2 HOH 133 433 74  HOH HOH B . 
F 2 HOH 134 434 466 HOH HOH B . 
F 2 HOH 135 435 550 HOH HOH B . 
F 2 HOH 136 436 630 HOH HOH B . 
F 2 HOH 137 437 455 HOH HOH B . 
F 2 HOH 138 438 63  HOH HOH B . 
F 2 HOH 139 439 83  HOH HOH B . 
F 2 HOH 140 440 376 HOH HOH B . 
F 2 HOH 141 441 481 HOH HOH B . 
F 2 HOH 142 442 631 HOH HOH B . 
F 2 HOH 143 443 784 HOH HOH B . 
F 2 HOH 144 444 712 HOH HOH B . 
F 2 HOH 145 445 638 HOH HOH B . 
F 2 HOH 146 446 697 HOH HOH B . 
F 2 HOH 147 447 615 HOH HOH B . 
F 2 HOH 148 448 215 HOH HOH B . 
F 2 HOH 149 449 52  HOH HOH B . 
F 2 HOH 150 450 401 HOH HOH B . 
F 2 HOH 151 451 581 HOH HOH B . 
F 2 HOH 152 452 369 HOH HOH B . 
F 2 HOH 153 453 570 HOH HOH B . 
F 2 HOH 154 454 194 HOH HOH B . 
F 2 HOH 155 455 686 HOH HOH B . 
F 2 HOH 156 456 619 HOH HOH B . 
F 2 HOH 157 457 665 HOH HOH B . 
F 2 HOH 158 458 744 HOH HOH B . 
F 2 HOH 159 459 750 HOH HOH B . 
F 2 HOH 160 460 336 HOH HOH B . 
F 2 HOH 161 461 559 HOH HOH B . 
F 2 HOH 162 462 9   HOH HOH B . 
F 2 HOH 163 463 342 HOH HOH B . 
F 2 HOH 164 464 675 HOH HOH B . 
F 2 HOH 165 465 805 HOH HOH B . 
F 2 HOH 166 466 710 HOH HOH B . 
F 2 HOH 167 467 454 HOH HOH B . 
F 2 HOH 168 468 554 HOH HOH B . 
F 2 HOH 169 469 745 HOH HOH B . 
F 2 HOH 170 470 794 HOH HOH B . 
F 2 HOH 171 471 810 HOH HOH B . 
F 2 HOH 172 472 134 HOH HOH B . 
F 2 HOH 173 473 611 HOH HOH B . 
F 2 HOH 174 474 315 HOH HOH B . 
F 2 HOH 175 475 785 HOH HOH B . 
F 2 HOH 176 476 537 HOH HOH B . 
F 2 HOH 177 477 767 HOH HOH B . 
F 2 HOH 178 478 613 HOH HOH B . 
F 2 HOH 179 479 598 HOH HOH B . 
F 2 HOH 180 480 787 HOH HOH B . 
F 2 HOH 181 481 281 HOH HOH B . 
F 2 HOH 182 482 577 HOH HOH B . 
F 2 HOH 183 483 7   HOH HOH B . 
F 2 HOH 184 484 602 HOH HOH B . 
F 2 HOH 185 485 526 HOH HOH B . 
F 2 HOH 186 486 479 HOH HOH B . 
F 2 HOH 187 487 726 HOH HOH B . 
F 2 HOH 188 488 573 HOH HOH B . 
F 2 HOH 189 489 735 HOH HOH B . 
F 2 HOH 190 490 435 HOH HOH B . 
F 2 HOH 191 491 296 HOH HOH B . 
F 2 HOH 192 492 284 HOH HOH B . 
F 2 HOH 193 493 623 HOH HOH B . 
F 2 HOH 194 494 815 HOH HOH B . 
F 2 HOH 195 495 606 HOH HOH B . 
F 2 HOH 196 496 461 HOH HOH B . 
F 2 HOH 197 497 567 HOH HOH B . 
F 2 HOH 198 498 356 HOH HOH B . 
F 2 HOH 199 499 67  HOH HOH B . 
F 2 HOH 200 500 632 HOH HOH B . 
F 2 HOH 201 501 396 HOH HOH B . 
F 2 HOH 202 502 459 HOH HOH B . 
F 2 HOH 203 503 490 HOH HOH B . 
F 2 HOH 204 504 389 HOH HOH B . 
F 2 HOH 205 505 765 HOH HOH B . 
F 2 HOH 206 506 575 HOH HOH B . 
F 2 HOH 207 507 730 HOH HOH B . 
F 2 HOH 208 508 626 HOH HOH B . 
F 2 HOH 209 509 685 HOH HOH B . 
F 2 HOH 210 510 326 HOH HOH B . 
F 2 HOH 211 511 761 HOH HOH B . 
F 2 HOH 212 512 120 HOH HOH B . 
F 2 HOH 213 513 277 HOH HOH B . 
G 2 HOH 1   301 582 HOH HOH C . 
G 2 HOH 2   302 572 HOH HOH C . 
G 2 HOH 3   303 506 HOH HOH C . 
G 2 HOH 4   304 205 HOH HOH C . 
G 2 HOH 5   305 430 HOH HOH C . 
G 2 HOH 6   306 94  HOH HOH C . 
G 2 HOH 7   307 406 HOH HOH C . 
G 2 HOH 8   308 645 HOH HOH C . 
G 2 HOH 9   309 238 HOH HOH C . 
G 2 HOH 10  310 22  HOH HOH C . 
G 2 HOH 11  311 167 HOH HOH C . 
G 2 HOH 12  312 334 HOH HOH C . 
G 2 HOH 13  313 163 HOH HOH C . 
G 2 HOH 14  314 162 HOH HOH C . 
G 2 HOH 15  315 534 HOH HOH C . 
G 2 HOH 16  316 239 HOH HOH C . 
G 2 HOH 17  317 299 HOH HOH C . 
G 2 HOH 18  318 341 HOH HOH C . 
G 2 HOH 19  319 197 HOH HOH C . 
G 2 HOH 20  320 776 HOH HOH C . 
G 2 HOH 21  321 689 HOH HOH C . 
G 2 HOH 22  322 211 HOH HOH C . 
G 2 HOH 23  323 8   HOH HOH C . 
G 2 HOH 24  324 641 HOH HOH C . 
G 2 HOH 25  325 380 HOH HOH C . 
G 2 HOH 26  326 245 HOH HOH C . 
G 2 HOH 27  327 60  HOH HOH C . 
G 2 HOH 28  328 90  HOH HOH C . 
G 2 HOH 29  329 50  HOH HOH C . 
G 2 HOH 30  330 13  HOH HOH C . 
G 2 HOH 31  331 727 HOH HOH C . 
G 2 HOH 32  332 213 HOH HOH C . 
G 2 HOH 33  333 65  HOH HOH C . 
G 2 HOH 34  334 172 HOH HOH C . 
G 2 HOH 35  335 122 HOH HOH C . 
G 2 HOH 36  336 137 HOH HOH C . 
G 2 HOH 37  337 754 HOH HOH C . 
G 2 HOH 38  338 671 HOH HOH C . 
G 2 HOH 39  339 499 HOH HOH C . 
G 2 HOH 40  340 198 HOH HOH C . 
G 2 HOH 41  341 207 HOH HOH C . 
G 2 HOH 42  342 333 HOH HOH C . 
G 2 HOH 43  343 155 HOH HOH C . 
G 2 HOH 44  344 339 HOH HOH C . 
G 2 HOH 45  345 318 HOH HOH C . 
G 2 HOH 46  346 64  HOH HOH C . 
G 2 HOH 47  347 594 HOH HOH C . 
G 2 HOH 48  348 191 HOH HOH C . 
G 2 HOH 49  349 181 HOH HOH C . 
G 2 HOH 50  350 699 HOH HOH C . 
G 2 HOH 51  351 49  HOH HOH C . 
G 2 HOH 52  352 257 HOH HOH C . 
G 2 HOH 53  353 135 HOH HOH C . 
G 2 HOH 54  354 700 HOH HOH C . 
G 2 HOH 55  355 158 HOH HOH C . 
G 2 HOH 56  356 71  HOH HOH C . 
G 2 HOH 57  357 53  HOH HOH C . 
G 2 HOH 58  358 80  HOH HOH C . 
G 2 HOH 59  359 169 HOH HOH C . 
G 2 HOH 60  360 212 HOH HOH C . 
G 2 HOH 61  361 382 HOH HOH C . 
G 2 HOH 62  362 21  HOH HOH C . 
G 2 HOH 63  363 140 HOH HOH C . 
G 2 HOH 64  364 417 HOH HOH C . 
G 2 HOH 65  365 351 HOH HOH C . 
G 2 HOH 66  366 520 HOH HOH C . 
G 2 HOH 67  367 330 HOH HOH C . 
G 2 HOH 68  368 701 HOH HOH C . 
G 2 HOH 69  369 208 HOH HOH C . 
G 2 HOH 70  370 182 HOH HOH C . 
G 2 HOH 71  371 136 HOH HOH C . 
G 2 HOH 72  372 41  HOH HOH C . 
G 2 HOH 73  373 497 HOH HOH C . 
G 2 HOH 74  374 418 HOH HOH C . 
G 2 HOH 75  375 360 HOH HOH C . 
G 2 HOH 76  376 478 HOH HOH C . 
G 2 HOH 77  377 95  HOH HOH C . 
G 2 HOH 78  378 679 HOH HOH C . 
G 2 HOH 79  379 56  HOH HOH C . 
G 2 HOH 80  380 58  HOH HOH C . 
G 2 HOH 81  381 302 HOH HOH C . 
G 2 HOH 82  382 410 HOH HOH C . 
G 2 HOH 83  383 226 HOH HOH C . 
G 2 HOH 84  384 233 HOH HOH C . 
G 2 HOH 85  385 132 HOH HOH C . 
G 2 HOH 86  386 524 HOH HOH C . 
G 2 HOH 87  387 387 HOH HOH C . 
G 2 HOH 88  388 190 HOH HOH C . 
G 2 HOH 89  389 204 HOH HOH C . 
G 2 HOH 90  390 678 HOH HOH C . 
G 2 HOH 91  391 47  HOH HOH C . 
G 2 HOH 92  392 649 HOH HOH C . 
G 2 HOH 93  393 384 HOH HOH C . 
G 2 HOH 94  394 653 HOH HOH C . 
G 2 HOH 95  395 439 HOH HOH C . 
G 2 HOH 96  396 717 HOH HOH C . 
G 2 HOH 97  397 501 HOH HOH C . 
G 2 HOH 98  398 398 HOH HOH C . 
G 2 HOH 99  399 434 HOH HOH C . 
G 2 HOH 100 400 231 HOH HOH C . 
G 2 HOH 101 401 364 HOH HOH C . 
G 2 HOH 102 402 556 HOH HOH C . 
G 2 HOH 103 403 541 HOH HOH C . 
G 2 HOH 104 404 457 HOH HOH C . 
G 2 HOH 105 405 143 HOH HOH C . 
G 2 HOH 106 406 264 HOH HOH C . 
G 2 HOH 107 407 374 HOH HOH C . 
G 2 HOH 108 408 429 HOH HOH C . 
G 2 HOH 109 409 471 HOH HOH C . 
G 2 HOH 110 410 560 HOH HOH C . 
G 2 HOH 111 411 790 HOH HOH C . 
G 2 HOH 112 412 656 HOH HOH C . 
G 2 HOH 113 413 303 HOH HOH C . 
G 2 HOH 114 414 267 HOH HOH C . 
G 2 HOH 115 415 706 HOH HOH C . 
G 2 HOH 116 416 283 HOH HOH C . 
G 2 HOH 117 417 676 HOH HOH C . 
G 2 HOH 118 418 557 HOH HOH C . 
G 2 HOH 119 419 663 HOH HOH C . 
G 2 HOH 120 420 112 HOH HOH C . 
G 2 HOH 121 421 266 HOH HOH C . 
G 2 HOH 122 422 633 HOH HOH C . 
G 2 HOH 123 423 200 HOH HOH C . 
G 2 HOH 124 424 106 HOH HOH C . 
G 2 HOH 125 425 317 HOH HOH C . 
G 2 HOH 126 426 713 HOH HOH C . 
G 2 HOH 127 427 433 HOH HOH C . 
G 2 HOH 128 428 625 HOH HOH C . 
G 2 HOH 129 429 166 HOH HOH C . 
G 2 HOH 130 430 66  HOH HOH C . 
G 2 HOH 131 431 73  HOH HOH C . 
G 2 HOH 132 432 441 HOH HOH C . 
G 2 HOH 133 433 733 HOH HOH C . 
G 2 HOH 134 434 329 HOH HOH C . 
G 2 HOH 135 435 337 HOH HOH C . 
G 2 HOH 136 436 588 HOH HOH C . 
G 2 HOH 137 437 462 HOH HOH C . 
G 2 HOH 138 438 595 HOH HOH C . 
G 2 HOH 139 439 252 HOH HOH C . 
G 2 HOH 140 440 465 HOH HOH C . 
G 2 HOH 141 441 312 HOH HOH C . 
G 2 HOH 142 442 592 HOH HOH C . 
G 2 HOH 143 443 440 HOH HOH C . 
G 2 HOH 144 444 659 HOH HOH C . 
G 2 HOH 145 445 3   HOH HOH C . 
G 2 HOH 146 446 463 HOH HOH C . 
G 2 HOH 147 447 709 HOH HOH C . 
G 2 HOH 148 448 746 HOH HOH C . 
G 2 HOH 149 449 609 HOH HOH C . 
G 2 HOH 150 450 431 HOH HOH C . 
G 2 HOH 151 451 373 HOH HOH C . 
G 2 HOH 152 452 287 HOH HOH C . 
G 2 HOH 153 453 803 HOH HOH C . 
G 2 HOH 154 454 770 HOH HOH C . 
G 2 HOH 155 455 725 HOH HOH C . 
G 2 HOH 156 456 734 HOH HOH C . 
G 2 HOH 157 457 807 HOH HOH C . 
G 2 HOH 158 458 548 HOH HOH C . 
G 2 HOH 159 459 792 HOH HOH C . 
G 2 HOH 160 460 698 HOH HOH C . 
G 2 HOH 161 461 617 HOH HOH C . 
G 2 HOH 162 462 468 HOH HOH C . 
G 2 HOH 163 463 580 HOH HOH C . 
G 2 HOH 164 464 489 HOH HOH C . 
G 2 HOH 165 465 187 HOH HOH C . 
G 2 HOH 166 466 275 HOH HOH C . 
G 2 HOH 167 467 282 HOH HOH C . 
G 2 HOH 168 468 590 HOH HOH C . 
G 2 HOH 169 469 690 HOH HOH C . 
G 2 HOH 170 470 593 HOH HOH C . 
G 2 HOH 171 471 443 HOH HOH C . 
G 2 HOH 172 472 661 HOH HOH C . 
G 2 HOH 173 473 600 HOH HOH C . 
G 2 HOH 174 474 338 HOH HOH C . 
G 2 HOH 175 475 500 HOH HOH C . 
G 2 HOH 176 476 708 HOH HOH C . 
G 2 HOH 177 477 288 HOH HOH C . 
G 2 HOH 178 478 801 HOH HOH C . 
G 2 HOH 179 479 768 HOH HOH C . 
G 2 HOH 180 480 782 HOH HOH C . 
G 2 HOH 181 481 752 HOH HOH C . 
G 2 HOH 182 482 743 HOH HOH C . 
G 2 HOH 183 483 68  HOH HOH C . 
G 2 HOH 184 484 186 HOH HOH C . 
G 2 HOH 185 485 421 HOH HOH C . 
G 2 HOH 186 486 496 HOH HOH C . 
G 2 HOH 187 487 568 HOH HOH C . 
G 2 HOH 188 488 438 HOH HOH C . 
G 2 HOH 189 489 405 HOH HOH C . 
G 2 HOH 190 490 624 HOH HOH C . 
G 2 HOH 191 491 753 HOH HOH C . 
G 2 HOH 192 492 413 HOH HOH C . 
G 2 HOH 193 493 703 HOH HOH C . 
G 2 HOH 194 494 272 HOH HOH C . 
G 2 HOH 195 495 416 HOH HOH C . 
G 2 HOH 196 496 777 HOH HOH C . 
H 2 HOH 1   301 372 HOH HOH D . 
H 2 HOH 2   302 464 HOH HOH D . 
H 2 HOH 3   303 392 HOH HOH D . 
H 2 HOH 4   304 100 HOH HOH D . 
H 2 HOH 5   305 248 HOH HOH D . 
H 2 HOH 6   306 353 HOH HOH D . 
H 2 HOH 7   307 111 HOH HOH D . 
H 2 HOH 8   308 722 HOH HOH D . 
H 2 HOH 9   309 314 HOH HOH D . 
H 2 HOH 10  310 152 HOH HOH D . 
H 2 HOH 11  311 425 HOH HOH D . 
H 2 HOH 12  312 629 HOH HOH D . 
H 2 HOH 13  313 153 HOH HOH D . 
H 2 HOH 14  314 184 HOH HOH D . 
H 2 HOH 15  315 361 HOH HOH D . 
H 2 HOH 16  316 423 HOH HOH D . 
H 2 HOH 17  317 88  HOH HOH D . 
H 2 HOH 18  318 145 HOH HOH D . 
H 2 HOH 19  319 323 HOH HOH D . 
H 2 HOH 20  320 116 HOH HOH D . 
H 2 HOH 21  321 28  HOH HOH D . 
H 2 HOH 22  322 121 HOH HOH D . 
H 2 HOH 23  323 249 HOH HOH D . 
H 2 HOH 24  324 10  HOH HOH D . 
H 2 HOH 25  325 381 HOH HOH D . 
H 2 HOH 26  326 786 HOH HOH D . 
H 2 HOH 27  327 449 HOH HOH D . 
H 2 HOH 28  328 224 HOH HOH D . 
H 2 HOH 29  329 78  HOH HOH D . 
H 2 HOH 30  330 87  HOH HOH D . 
H 2 HOH 31  331 14  HOH HOH D . 
H 2 HOH 32  332 18  HOH HOH D . 
H 2 HOH 33  333 802 HOH HOH D . 
H 2 HOH 34  334 724 HOH HOH D . 
H 2 HOH 35  335 379 HOH HOH D . 
H 2 HOH 36  336 214 HOH HOH D . 
H 2 HOH 37  337 124 HOH HOH D . 
H 2 HOH 38  338 240 HOH HOH D . 
H 2 HOH 39  339 195 HOH HOH D . 
H 2 HOH 40  340 579 HOH HOH D . 
H 2 HOH 41  341 505 HOH HOH D . 
H 2 HOH 42  342 210 HOH HOH D . 
H 2 HOH 43  343 39  HOH HOH D . 
H 2 HOH 44  344 758 HOH HOH D . 
H 2 HOH 45  345 173 HOH HOH D . 
H 2 HOH 46  346 378 HOH HOH D . 
H 2 HOH 47  347 48  HOH HOH D . 
H 2 HOH 48  348 209 HOH HOH D . 
H 2 HOH 49  349 278 HOH HOH D . 
H 2 HOH 50  350 156 HOH HOH D . 
H 2 HOH 51  351 138 HOH HOH D . 
H 2 HOH 52  352 34  HOH HOH D . 
H 2 HOH 53  353 368 HOH HOH D . 
H 2 HOH 54  354 160 HOH HOH D . 
H 2 HOH 55  355 23  HOH HOH D . 
H 2 HOH 56  356 660 HOH HOH D . 
H 2 HOH 57  357 760 HOH HOH D . 
H 2 HOH 58  358 311 HOH HOH D . 
H 2 HOH 59  359 316 HOH HOH D . 
H 2 HOH 60  360 269 HOH HOH D . 
H 2 HOH 61  361 657 HOH HOH D . 
H 2 HOH 62  362 320 HOH HOH D . 
H 2 HOH 63  363 109 HOH HOH D . 
H 2 HOH 64  364 371 HOH HOH D . 
H 2 HOH 65  365 183 HOH HOH D . 
H 2 HOH 66  366 646 HOH HOH D . 
H 2 HOH 67  367 150 HOH HOH D . 
H 2 HOH 68  368 755 HOH HOH D . 
H 2 HOH 69  369 692 HOH HOH D . 
H 2 HOH 70  370 131 HOH HOH D . 
H 2 HOH 71  371 350 HOH HOH D . 
H 2 HOH 72  372 383 HOH HOH D . 
H 2 HOH 73  373 265 HOH HOH D . 
H 2 HOH 74  374 102 HOH HOH D . 
H 2 HOH 75  375 148 HOH HOH D . 
H 2 HOH 76  376 253 HOH HOH D . 
H 2 HOH 77  377 355 HOH HOH D . 
H 2 HOH 78  378 19  HOH HOH D . 
H 2 HOH 79  379 711 HOH HOH D . 
H 2 HOH 80  380 119 HOH HOH D . 
H 2 HOH 81  381 96  HOH HOH D . 
H 2 HOH 82  382 110 HOH HOH D . 
H 2 HOH 83  383 789 HOH HOH D . 
H 2 HOH 84  384 26  HOH HOH D . 
H 2 HOH 85  385 159 HOH HOH D . 
H 2 HOH 86  386 340 HOH HOH D . 
H 2 HOH 87  387 546 HOH HOH D . 
H 2 HOH 88  388 811 HOH HOH D . 
H 2 HOH 89  389 178 HOH HOH D . 
H 2 HOH 90  390 129 HOH HOH D . 
H 2 HOH 91  391 547 HOH HOH D . 
H 2 HOH 92  392 532 HOH HOH D . 
H 2 HOH 93  393 85  HOH HOH D . 
H 2 HOH 94  394 35  HOH HOH D . 
H 2 HOH 95  395 642 HOH HOH D . 
H 2 HOH 96  396 800 HOH HOH D . 
H 2 HOH 97  397 386 HOH HOH D . 
H 2 HOH 98  398 199 HOH HOH D . 
H 2 HOH 99  399 634 HOH HOH D . 
H 2 HOH 100 400 650 HOH HOH D . 
H 2 HOH 101 401 732 HOH HOH D . 
H 2 HOH 102 402 444 HOH HOH D . 
H 2 HOH 103 403 5   HOH HOH D . 
H 2 HOH 104 404 766 HOH HOH D . 
H 2 HOH 105 405 300 HOH HOH D . 
H 2 HOH 106 406 246 HOH HOH D . 
H 2 HOH 107 407 614 HOH HOH D . 
H 2 HOH 108 408 714 HOH HOH D . 
H 2 HOH 109 409 349 HOH HOH D . 
H 2 HOH 110 410 344 HOH HOH D . 
H 2 HOH 111 411 491 HOH HOH D . 
H 2 HOH 112 412 189 HOH HOH D . 
H 2 HOH 113 413 223 HOH HOH D . 
H 2 HOH 114 414 533 HOH HOH D . 
H 2 HOH 115 415 591 HOH HOH D . 
H 2 HOH 116 416 352 HOH HOH D . 
H 2 HOH 117 417 40  HOH HOH D . 
H 2 HOH 118 418 101 HOH HOH D . 
H 2 HOH 119 419 164 HOH HOH D . 
H 2 HOH 120 420 55  HOH HOH D . 
H 2 HOH 121 421 301 HOH HOH D . 
H 2 HOH 122 422 644 HOH HOH D . 
H 2 HOH 123 423 622 HOH HOH D . 
H 2 HOH 124 424 549 HOH HOH D . 
H 2 HOH 125 425 241 HOH HOH D . 
H 2 HOH 126 426 450 HOH HOH D . 
H 2 HOH 127 427 759 HOH HOH D . 
H 2 HOH 128 428 620 HOH HOH D . 
H 2 HOH 129 429 354 HOH HOH D . 
H 2 HOH 130 430 774 HOH HOH D . 
H 2 HOH 131 431 27  HOH HOH D . 
H 2 HOH 132 432 448 HOH HOH D . 
H 2 HOH 133 433 669 HOH HOH D . 
H 2 HOH 134 434 482 HOH HOH D . 
H 2 HOH 135 435 447 HOH HOH D . 
H 2 HOH 136 436 674 HOH HOH D . 
H 2 HOH 137 437 545 HOH HOH D . 
H 2 HOH 138 438 716 HOH HOH D . 
H 2 HOH 139 439 33  HOH HOH D . 
H 2 HOH 140 440 816 HOH HOH D . 
H 2 HOH 141 441 428 HOH HOH D . 
H 2 HOH 142 442 367 HOH HOH D . 
H 2 HOH 143 443 517 HOH HOH D . 
H 2 HOH 144 444 576 HOH HOH D . 
H 2 HOH 145 445 84  HOH HOH D . 
H 2 HOH 146 446 1   HOH HOH D . 
H 2 HOH 147 447 764 HOH HOH D . 
H 2 HOH 148 448 808 HOH HOH D . 
H 2 HOH 149 449 409 HOH HOH D . 
H 2 HOH 150 450 174 HOH HOH D . 
H 2 HOH 151 451 519 HOH HOH D . 
H 2 HOH 152 452 359 HOH HOH D . 
H 2 HOH 153 453 343 HOH HOH D . 
H 2 HOH 154 454 451 HOH HOH D . 
H 2 HOH 155 455 540 HOH HOH D . 
H 2 HOH 156 456 723 HOH HOH D . 
H 2 HOH 157 457 424 HOH HOH D . 
H 2 HOH 158 458 737 HOH HOH D . 
H 2 HOH 159 459 682 HOH HOH D . 
H 2 HOH 160 460 666 HOH HOH D . 
H 2 HOH 161 461 426 HOH HOH D . 
H 2 HOH 162 462 319 HOH HOH D . 
H 2 HOH 163 463 274 HOH HOH D . 
H 2 HOH 164 464 740 HOH HOH D . 
H 2 HOH 165 465 636 HOH HOH D . 
H 2 HOH 166 466 637 HOH HOH D . 
H 2 HOH 167 467 414 HOH HOH D . 
H 2 HOH 168 468 648 HOH HOH D . 
H 2 HOH 169 469 285 HOH HOH D . 
H 2 HOH 170 470 385 HOH HOH D . 
H 2 HOH 171 471 516 HOH HOH D . 
H 2 HOH 172 472 793 HOH HOH D . 
H 2 HOH 173 473 672 HOH HOH D . 
H 2 HOH 174 474 647 HOH HOH D . 
H 2 HOH 175 475 394 HOH HOH D . 
H 2 HOH 176 476 788 HOH HOH D . 
H 2 HOH 177 477 510 HOH HOH D . 
H 2 HOH 178 478 544 HOH HOH D . 
H 2 HOH 179 479 483 HOH HOH D . 
H 2 HOH 180 480 762 HOH HOH D . 
H 2 HOH 181 481 736 HOH HOH D . 
H 2 HOH 182 482 390 HOH HOH D . 
H 2 HOH 183 483 773 HOH HOH D . 
H 2 HOH 184 484 562 HOH HOH D . 
H 2 HOH 185 485 578 HOH HOH D . 
H 2 HOH 186 486 747 HOH HOH D . 
H 2 HOH 187 487 453 HOH HOH D . 
H 2 HOH 188 488 528 HOH HOH D . 
H 2 HOH 189 489 44  HOH HOH D . 
H 2 HOH 190 490 607 HOH HOH D . 
H 2 HOH 191 491 530 HOH HOH D . 
H 2 HOH 192 492 280 HOH HOH D . 
H 2 HOH 193 493 804 HOH HOH D . 
H 2 HOH 194 494 702 HOH HOH D . 
H 2 HOH 195 495 720 HOH HOH D . 
H 2 HOH 196 496 780 HOH HOH D . 
H 2 HOH 197 497 756 HOH HOH D . 
H 2 HOH 198 498 407 HOH HOH D . 
H 2 HOH 199 499 640 HOH HOH D . 
H 2 HOH 200 500 670 HOH HOH D . 
H 2 HOH 201 501 809 HOH HOH D . 
H 2 HOH 202 502 202 HOH HOH D . 
H 2 HOH 203 503 370 HOH HOH D . 
H 2 HOH 204 504 693 HOH HOH D . 
H 2 HOH 205 505 664 HOH HOH D . 
H 2 HOH 206 506 587 HOH HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A LYS 131 ? NZ  ? A LYS 129 NZ  
2 1 Y 1 A ILE 171 ? CD1 ? A ILE 169 CD1 
3 1 Y 1 B LYS 131 ? NZ  ? B LYS 129 NZ  
4 1 Y 1 B ILE 171 ? CD1 ? B ILE 169 CD1 
5 1 Y 1 C LYS 131 ? NZ  ? C LYS 129 NZ  
6 1 Y 1 C ILE 171 ? CD1 ? C ILE 169 CD1 
7 1 Y 1 D LYS 131 ? NZ  ? D LYS 129 NZ  
8 1 Y 1 D ILE 171 ? CD1 ? D ILE 169 CD1 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.19.2_4158: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8JL2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     76.345 
_cell.length_a_esd                 ? 
_cell.length_b                     80.548 
_cell.length_b_esd                 ? 
_cell.length_c                     179.780 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8JL2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8JL2 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.69 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          54.32 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1M sodium Tris pH 9.5, 0.8M sodium dihydrogen phosphate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            298 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     193 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'MARMOSAIC 225 mm CCD' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-06-14 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.00000 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PAL/PLS BEAMLINE 5C (4A)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.00000 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   '5C (4A)' 
_diffrn_source.pdbx_synchrotron_site       PAL/PLS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8JL2 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.75 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     109847 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                10.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.2 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.284 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.100 
_reflns.pdbx_Rpim_I_all                                0.028 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       1160484 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.095 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
1.75 1.81  ? ? ? ? ? ? 9194  ? ? ? ? ? ? ? ? ? ? ? 6.8  0.808 ? ? 0.468 0.168 ? 1  1 0.572 0.853 ? 83.0 ? 0.434 ? ? ? ? ? ? ? ? ? 
1.81 1.89  ? ? ? ? ? ? 10965 ? ? ? ? ? ? ? ? ? ? ? 8.1  0.926 ? ? 0.419 0.140 ? 2  1 0.789 0.939 ? 98.5 ? 0.394 ? ? ? ? ? ? ? ? ? 
1.89 1.97  ? ? ? ? ? ? 11004 ? ? ? ? ? ? ? ? ? ? ? 8.9  1.066 ? ? 0.357 0.113 ? 3  1 0.900 0.973 ? 98.7 ? 0.337 ? ? ? ? ? ? ? ? ? 
1.97 2.07  ? ? ? ? ? ? 11034 ? ? ? ? ? ? ? ? ? ? ? 9.9  1.209 ? ? 0.294 0.089 ? 4  1 0.949 0.987 ? 99.0 ? 0.280 ? ? ? ? ? ? ? ? ? 
2.07 2.20  ? ? ? ? ? ? 11081 ? ? ? ? ? ? ? ? ? ? ? 10.5 1.282 ? ? 0.238 0.070 ? 5  1 0.974 0.993 ? 99.3 ? 0.227 ? ? ? ? ? ? ? ? ? 
2.20 2.38  ? ? ? ? ? ? 11131 ? ? ? ? ? ? ? ? ? ? ? 10.8 1.291 ? ? 0.192 0.056 ? 6  1 0.986 0.997 ? 99.4 ? 0.184 ? ? ? ? ? ? ? ? ? 
2.38 2.61  ? ? ? ? ? ? 11154 ? ? ? ? ? ? ? ? ? ? ? 11.5 1.331 ? ? 0.144 0.041 ? 7  1 0.994 0.998 ? 99.6 ? 0.138 ? ? ? ? ? ? ? ? ? 
2.61 2.99  ? ? ? ? ? ? 11243 ? ? ? ? ? ? ? ? ? ? ? 12.1 1.364 ? ? 0.109 0.030 ? 8  1 0.997 0.999 ? 99.7 ? 0.105 ? ? ? ? ? ? ? ? ? 
2.99 3.77  ? ? ? ? ? ? 11341 ? ? ? ? ? ? ? ? ? ? ? 13.2 1.464 ? ? 0.068 0.018 ? 9  1 0.999 1.000 ? 99.8 ? 0.066 ? ? ? ? ? ? ? ? ? 
3.77 50.00 ? ? ? ? ? ? 11700 ? ? ? ? ? ? ? ? ? ? ? 13.0 1.558 ? ? 0.053 0.014 ? 10 1 0.999 1.000 ? 99.4 ? 0.051 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8JL2 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.76 
_refine.ls_d_res_low                             33.12 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     109807 
_refine.ls_number_reflns_R_free                  1987 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.77 
_refine.ls_percent_reflns_R_free                 1.81 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1911 
_refine.ls_R_factor_R_free                       0.2176 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1906 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.48 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 19.52 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.19 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.76 
_refine_hist.d_res_low                        33.12 
_refine_hist.number_atoms_solvent             811 
_refine_hist.number_atoms_total               8039 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7228 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008 ? 7396 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.121 ? 9996 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 8.380 ? 968  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.069 ? 1068 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.009 ? 1304 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.76 1.80  . . 120 7085 92.00  . . . . 0.2756 . . . . . . . . . . . 0.3266 
'X-RAY DIFFRACTION' 1.80 1.85  . . 151 7572 98.00  . . . . 0.2605 . . . . . . . . . . . 0.3003 
'X-RAY DIFFRACTION' 1.85 1.90  . . 139 7622 99.00  . . . . 0.2373 . . . . . . . . . . . 0.2625 
'X-RAY DIFFRACTION' 1.90 1.96  . . 139 7631 99.00  . . . . 0.2224 . . . . . . . . . . . 0.2505 
'X-RAY DIFFRACTION' 1.96 2.03  . . 157 7582 99.00  . . . . 0.1956 . . . . . . . . . . . 0.2330 
'X-RAY DIFFRACTION' 2.03 2.12  . . 132 7701 99.00  . . . . 0.1917 . . . . . . . . . . . 0.2271 
'X-RAY DIFFRACTION' 2.12 2.21  . . 136 7688 99.00  . . . . 0.1854 . . . . . . . . . . . 0.2078 
'X-RAY DIFFRACTION' 2.21 2.33  . . 154 7693 99.00  . . . . 0.1877 . . . . . . . . . . . 0.2132 
'X-RAY DIFFRACTION' 2.33 2.48  . . 142 7734 99.00  . . . . 0.1890 . . . . . . . . . . . 0.2275 
'X-RAY DIFFRACTION' 2.48 2.67  . . 134 7775 100.00 . . . . 0.1866 . . . . . . . . . . . 0.2020 
'X-RAY DIFFRACTION' 2.67 2.93  . . 154 7811 100.00 . . . . 0.1916 . . . . . . . . . . . 0.2202 
'X-RAY DIFFRACTION' 2.93 3.36  . . 142 7839 100.00 . . . . 0.1748 . . . . . . . . . . . 0.2088 
'X-RAY DIFFRACTION' 3.36 4.23  . . 143 7912 100.00 . . . . 0.1675 . . . . . . . . . . . 0.1703 
'X-RAY DIFFRACTION' 4.23 33.12 . . 144 8175 100.00 . . . . 0.1820 . . . . . . . . . . . 0.2186 
# 
_struct.entry_id                     8JL2 
_struct.title                        'Crystal structure of the Green fluorescent protein SE_A277 variant at pH 9.5' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8JL2 
_struct_keywords.text            'bioimaging, Sensor. GFP, FLUORESCENT PROTEIN' 
_struct_keywords.pdbx_keywords   'FLUORESCENT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    GFP_AEQVI 
_struct_ref.pdbx_db_accession          P42212 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFSYGVQCFSRYPDHMKQ
HDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNG
IKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGITHGMDELYK
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8JL2 A 1 ? 236 ? P42212 1 ? 238 ? 1 238 
2 1 8JL2 B 1 ? 236 ? P42212 1 ? 238 ? 1 238 
3 1 8JL2 C 1 ? 236 ? P42212 1 ? 238 ? 1 238 
4 1 8JL2 D 1 ? 236 ? P42212 1 ? 238 ? 1 238 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8JL2 LEU A 64  ? UNP P42212 PHE 64  'engineered mutation' 64  1  
1 8JL2 CRO A 65  ? UNP P42212 SER 65  chromophore           66  2  
1 8JL2 CRO A 65  ? UNP P42212 TYR 66  chromophore           66  3  
1 8JL2 CRO A 65  ? UNP P42212 GLY 67  chromophore           66  4  
1 8JL2 ARG A 78  ? UNP P42212 GLN 80  'engineered mutation' 80  5  
1 8JL2 ASP A 145 ? UNP P42212 SER 147 'engineered mutation' 147 6  
1 8JL2 GLN A 147 ? UNP P42212 ASN 149 'engineered mutation' 149 7  
1 8JL2 ALA A 161 ? UNP P42212 VAL 163 'engineered mutation' 163 8  
1 8JL2 GLY A 173 ? UNP P42212 SER 175 'engineered mutation' 175 9  
1 8JL2 PHE A 200 ? UNP P42212 SER 202 'engineered mutation' 202 10 
1 8JL2 THR A 202 ? UNP P42212 GLN 204 'engineered mutation' 204 11 
1 8JL2 THR A 204 ? UNP P42212 ALA 206 'engineered mutation' 206 12 
2 8JL2 LEU B 64  ? UNP P42212 PHE 64  'engineered mutation' 64  13 
2 8JL2 CRO B 65  ? UNP P42212 SER 65  chromophore           66  14 
2 8JL2 CRO B 65  ? UNP P42212 TYR 66  chromophore           66  15 
2 8JL2 CRO B 65  ? UNP P42212 GLY 67  chromophore           66  16 
2 8JL2 ARG B 78  ? UNP P42212 GLN 80  'engineered mutation' 80  17 
2 8JL2 ASP B 145 ? UNP P42212 SER 147 'engineered mutation' 147 18 
2 8JL2 GLN B 147 ? UNP P42212 ASN 149 'engineered mutation' 149 19 
2 8JL2 ALA B 161 ? UNP P42212 VAL 163 'engineered mutation' 163 20 
2 8JL2 GLY B 173 ? UNP P42212 SER 175 'engineered mutation' 175 21 
2 8JL2 PHE B 200 ? UNP P42212 SER 202 'engineered mutation' 202 22 
2 8JL2 THR B 202 ? UNP P42212 GLN 204 'engineered mutation' 204 23 
2 8JL2 THR B 204 ? UNP P42212 ALA 206 'engineered mutation' 206 24 
3 8JL2 LEU C 64  ? UNP P42212 PHE 64  'engineered mutation' 64  25 
3 8JL2 CRO C 65  ? UNP P42212 SER 65  chromophore           66  26 
3 8JL2 CRO C 65  ? UNP P42212 TYR 66  chromophore           66  27 
3 8JL2 CRO C 65  ? UNP P42212 GLY 67  chromophore           66  28 
3 8JL2 ARG C 78  ? UNP P42212 GLN 80  'engineered mutation' 80  29 
3 8JL2 ASP C 145 ? UNP P42212 SER 147 'engineered mutation' 147 30 
3 8JL2 GLN C 147 ? UNP P42212 ASN 149 'engineered mutation' 149 31 
3 8JL2 ALA C 161 ? UNP P42212 VAL 163 'engineered mutation' 163 32 
3 8JL2 GLY C 173 ? UNP P42212 SER 175 'engineered mutation' 175 33 
3 8JL2 PHE C 200 ? UNP P42212 SER 202 'engineered mutation' 202 34 
3 8JL2 THR C 202 ? UNP P42212 GLN 204 'engineered mutation' 204 35 
3 8JL2 THR C 204 ? UNP P42212 ALA 206 'engineered mutation' 206 36 
4 8JL2 LEU D 64  ? UNP P42212 PHE 64  'engineered mutation' 64  37 
4 8JL2 CRO D 65  ? UNP P42212 SER 65  chromophore           66  38 
4 8JL2 CRO D 65  ? UNP P42212 TYR 66  chromophore           66  39 
4 8JL2 CRO D 65  ? UNP P42212 GLY 67  chromophore           66  40 
4 8JL2 ARG D 78  ? UNP P42212 GLN 80  'engineered mutation' 80  41 
4 8JL2 ASP D 145 ? UNP P42212 SER 147 'engineered mutation' 147 42 
4 8JL2 GLN D 147 ? UNP P42212 ASN 149 'engineered mutation' 149 43 
4 8JL2 ALA D 161 ? UNP P42212 VAL 163 'engineered mutation' 163 44 
4 8JL2 GLY D 173 ? UNP P42212 SER 175 'engineered mutation' 175 45 
4 8JL2 PHE D 200 ? UNP P42212 SER 202 'engineered mutation' 202 46 
4 8JL2 THR D 202 ? UNP P42212 GLN 204 'engineered mutation' 204 47 
4 8JL2 THR D 204 ? UNP P42212 ALA 206 'engineered mutation' 206 48 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
4 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,E 
2 1 B,F 
3 1 C,G 
4 1 D,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 4   ? THR A 9   ? GLY A 4   THR A 9   5 ? 6 
HELX_P HELX_P2  AA2 PRO A 56  ? VAL A 61  ? PRO A 56  VAL A 61  5 ? 6 
HELX_P HELX_P3  AA3 VAL A 66  ? SER A 70  ? VAL A 68  SER A 72  5 ? 5 
HELX_P HELX_P4  AA4 PRO A 73  ? LYS A 77  ? PRO A 75  LYS A 79  5 ? 5 
HELX_P HELX_P5  AA5 ASP A 80  ? ALA A 85  ? ASP A 82  ALA A 87  1 ? 6 
HELX_P HELX_P6  AA6 GLY B 4   ? THR B 9   ? GLY B 4   THR B 9   5 ? 6 
HELX_P HELX_P7  AA7 PRO B 56  ? VAL B 61  ? PRO B 56  VAL B 61  5 ? 6 
HELX_P HELX_P8  AA8 VAL B 66  ? SER B 70  ? VAL B 68  SER B 72  5 ? 5 
HELX_P HELX_P9  AA9 PRO B 73  ? LYS B 77  ? PRO B 75  LYS B 79  5 ? 5 
HELX_P HELX_P10 AB1 ASP B 80  ? ALA B 85  ? ASP B 82  ALA B 87  1 ? 6 
HELX_P HELX_P11 AB2 GLY C 4   ? THR C 9   ? GLY C 4   THR C 9   5 ? 6 
HELX_P HELX_P12 AB3 PRO C 56  ? VAL C 61  ? PRO C 56  VAL C 61  5 ? 6 
HELX_P HELX_P13 AB4 VAL C 66  ? SER C 70  ? VAL C 68  SER C 72  5 ? 5 
HELX_P HELX_P14 AB5 PRO C 73  ? HIS C 79  ? PRO C 75  HIS C 81  5 ? 7 
HELX_P HELX_P15 AB6 ASP C 80  ? ALA C 85  ? ASP C 82  ALA C 87  1 ? 6 
HELX_P HELX_P16 AB7 LYS D 3   ? THR D 9   ? LYS D 3   THR D 9   5 ? 7 
HELX_P HELX_P17 AB8 PRO D 56  ? VAL D 61  ? PRO D 56  VAL D 61  5 ? 6 
HELX_P HELX_P18 AB9 VAL D 66  ? SER D 70  ? VAL D 68  SER D 72  5 ? 5 
HELX_P HELX_P19 AC1 ASP D 80  ? ALA D 85  ? ASP D 82  ALA D 87  1 ? 6 
HELX_P HELX_P20 AC2 LYS D 154 ? ASN D 157 ? LYS D 156 ASN D 159 5 ? 4 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A LEU 64 C  ? ? ? 1_555 A CRO 65 N1 ? ? A LEU 64 A CRO 66 1_555 ? ? ? ? ? ? ? 1.412 ? ? 
covale2 covale both ? A CRO 65 C3 ? ? ? 1_555 A VAL 66 N  ? ? A CRO 66 A VAL 68 1_555 ? ? ? ? ? ? ? 1.301 ? ? 
covale3 covale both ? B LEU 64 C  ? ? ? 1_555 B CRO 65 N1 ? ? B LEU 64 B CRO 66 1_555 ? ? ? ? ? ? ? 1.398 ? ? 
covale4 covale both ? B CRO 65 C3 ? ? ? 1_555 B VAL 66 N  ? ? B CRO 66 B VAL 68 1_555 ? ? ? ? ? ? ? 1.247 ? ? 
covale5 covale both ? C LEU 64 C  ? ? ? 1_555 C CRO 65 N1 ? ? C LEU 64 C CRO 66 1_555 ? ? ? ? ? ? ? 1.413 ? ? 
covale6 covale both ? C CRO 65 C3 ? ? ? 1_555 C VAL 66 N  ? ? C CRO 66 C VAL 68 1_555 ? ? ? ? ? ? ? 1.394 ? ? 
covale7 covale both ? D LEU 64 C  ? ? ? 1_555 D CRO 65 N1 ? ? D LEU 64 D CRO 66 1_555 ? ? ? ? ? ? ? 1.373 ? ? 
covale8 covale both ? D CRO 65 C3 ? ? ? 1_555 D VAL 66 N  ? ? D CRO 66 D VAL 68 1_555 ? ? ? ? ? ? ? 1.300 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CRO A 65 ? . . . . CRO A 66 ? 1_555 . . . . . . . 'THR, TYR, GLY' 1 CRO None Chromophore/chromophore-like 
2 CRO B 65 ? . . . . CRO B 66 ? 1_555 . . . . . . . 'THR, TYR, GLY' 1 CRO None Chromophore/chromophore-like 
3 CRO C 65 ? . . . . CRO C 66 ? 1_555 . . . . . . . 'THR, TYR, GLY' 1 CRO None Chromophore/chromophore-like 
4 CRO D 65 ? . . . . CRO D 66 ? 1_555 . . . . . . . 'THR, TYR, GLY' 1 CRO None Chromophore/chromophore-like 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 MET 86 A . ? MET 88 A PRO 87 A ? PRO 89 A 1 3.25 
2 MET 86 B . ? MET 88 B PRO 87 B ? PRO 89 B 1 1.84 
3 MET 86 C . ? MET 88 C PRO 87 C ? PRO 89 C 1 2.67 
4 MET 86 D . ? MET 88 D PRO 87 D ? PRO 89 D 1 7.56 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 12 ? 
AA2 ? 12 ? 
AA3 ? 12 ? 
AA4 ? 12 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA1 7  8  ? anti-parallel 
AA1 8  9  ? anti-parallel 
AA1 9  10 ? anti-parallel 
AA1 10 11 ? anti-parallel 
AA1 11 12 ? parallel      
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA2 5  6  ? anti-parallel 
AA2 6  7  ? anti-parallel 
AA2 7  8  ? anti-parallel 
AA2 8  9  ? anti-parallel 
AA2 9  10 ? anti-parallel 
AA2 10 11 ? anti-parallel 
AA2 11 12 ? parallel      
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
AA3 5  6  ? anti-parallel 
AA3 6  7  ? anti-parallel 
AA3 7  8  ? anti-parallel 
AA3 8  9  ? anti-parallel 
AA3 9  10 ? anti-parallel 
AA3 10 11 ? anti-parallel 
AA3 11 12 ? parallel      
AA4 1  2  ? anti-parallel 
AA4 2  3  ? anti-parallel 
AA4 3  4  ? anti-parallel 
AA4 4  5  ? anti-parallel 
AA4 5  6  ? anti-parallel 
AA4 6  7  ? anti-parallel 
AA4 7  8  ? anti-parallel 
AA4 8  9  ? anti-parallel 
AA4 9  10 ? anti-parallel 
AA4 10 11 ? anti-parallel 
AA4 11 12 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  VAL A 11  ? VAL A 22  ? VAL A 11  VAL A 22  
AA1 2  HIS A 25  ? ASP A 36  ? HIS A 25  ASP A 36  
AA1 3  LYS A 41  ? CYS A 48  ? LYS A 41  CYS A 48  
AA1 4  HIS A 215 ? ALA A 225 ? HIS A 217 ALA A 227 
AA1 5  HIS A 197 ? SER A 206 ? HIS A 199 SER A 208 
AA1 6  VAL A 148 ? ASP A 153 ? VAL A 150 ASP A 155 
AA1 7  GLY A 158 ? ASN A 168 ? GLY A 160 ASN A 170 
AA1 8  VAL A 174 ? PRO A 185 ? VAL A 176 PRO A 187 
AA1 9  TYR A 90  ? PHE A 98  ? TYR A 92  PHE A 100 
AA1 10 ASN A 103 ? GLU A 113 ? ASN A 105 GLU A 115 
AA1 11 THR A 116 ? ILE A 126 ? THR A 118 ILE A 128 
AA1 12 VAL A 11  ? VAL A 22  ? VAL A 11  VAL A 22  
AA2 1  VAL B 12  ? VAL B 22  ? VAL B 12  VAL B 22  
AA2 2  HIS B 25  ? ASP B 36  ? HIS B 25  ASP B 36  
AA2 3  LYS B 41  ? CYS B 48  ? LYS B 41  CYS B 48  
AA2 4  HIS B 215 ? ALA B 225 ? HIS B 217 ALA B 227 
AA2 5  HIS B 197 ? SER B 206 ? HIS B 199 SER B 208 
AA2 6  VAL B 148 ? ASP B 153 ? VAL B 150 ASP B 155 
AA2 7  GLY B 158 ? ASN B 168 ? GLY B 160 ASN B 170 
AA2 8  VAL B 174 ? PRO B 185 ? VAL B 176 PRO B 187 
AA2 9  TYR B 90  ? PHE B 98  ? TYR B 92  PHE B 100 
AA2 10 ASN B 103 ? GLU B 113 ? ASN B 105 GLU B 115 
AA2 11 THR B 116 ? ILE B 126 ? THR B 118 ILE B 128 
AA2 12 VAL B 12  ? VAL B 22  ? VAL B 12  VAL B 22  
AA3 1  VAL C 11  ? VAL C 22  ? VAL C 11  VAL C 22  
AA3 2  HIS C 25  ? ASP C 36  ? HIS C 25  ASP C 36  
AA3 3  LYS C 41  ? CYS C 48  ? LYS C 41  CYS C 48  
AA3 4  HIS C 215 ? ALA C 225 ? HIS C 217 ALA C 227 
AA3 5  HIS C 197 ? SER C 206 ? HIS C 199 SER C 208 
AA3 6  VAL C 148 ? ASP C 153 ? VAL C 150 ASP C 155 
AA3 7  GLY C 158 ? ASN C 168 ? GLY C 160 ASN C 170 
AA3 8  VAL C 174 ? PRO C 185 ? VAL C 176 PRO C 187 
AA3 9  TYR C 90  ? PHE C 98  ? TYR C 92  PHE C 100 
AA3 10 ASN C 103 ? GLU C 113 ? ASN C 105 GLU C 115 
AA3 11 THR C 116 ? ILE C 126 ? THR C 118 ILE C 128 
AA3 12 VAL C 11  ? VAL C 22  ? VAL C 11  VAL C 22  
AA4 1  VAL D 12  ? VAL D 22  ? VAL D 12  VAL D 22  
AA4 2  HIS D 25  ? ASP D 36  ? HIS D 25  ASP D 36  
AA4 3  LYS D 41  ? CYS D 48  ? LYS D 41  CYS D 48  
AA4 4  HIS D 215 ? ALA D 225 ? HIS D 217 ALA D 227 
AA4 5  HIS D 197 ? SER D 206 ? HIS D 199 SER D 208 
AA4 6  VAL D 148 ? ASP D 153 ? VAL D 150 ASP D 155 
AA4 7  GLY D 158 ? ASN D 168 ? GLY D 160 ASN D 170 
AA4 8  VAL D 174 ? PRO D 185 ? VAL D 176 PRO D 187 
AA4 9  TYR D 90  ? PHE D 98  ? TYR D 92  PHE D 100 
AA4 10 ASN D 103 ? GLU D 113 ? ASN D 105 GLU D 115 
AA4 11 THR D 116 ? ILE D 126 ? THR D 118 ILE D 128 
AA4 12 VAL D 12  ? VAL D 22  ? VAL D 12  VAL D 22  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N LEU A 18  ? N LEU A 18  O VAL A 29  ? O VAL A 29  
AA1 2  3  N ASP A 36  ? N ASP A 36  O LYS A 41  ? O LYS A 41  
AA1 3  4  N LEU A 44  ? N LEU A 44  O LEU A 218 ? O LEU A 220 
AA1 4  5  O ALA A 225 ? O ALA A 227 N TYR A 198 ? N TYR A 200 
AA1 5  6  O HIS A 197 ? O HIS A 199 N ILE A 150 ? N ILE A 152 
AA1 6  7  N ASP A 153 ? N ASP A 155 O GLY A 158 ? O GLY A 160 
AA1 7  8  N HIS A 167 ? N HIS A 169 O GLN A 175 ? O GLN A 177 
AA1 8  9  O THR A 184 ? O THR A 186 N VAL A 91  ? N VAL A 93  
AA1 9  10 N GLN A 92  ? N GLN A 94  O ALA A 108 ? O ALA A 110 
AA1 10 11 N LYS A 111 ? N LYS A 113 O VAL A 118 ? O VAL A 120 
AA1 11 12 O GLY A 125 ? O GLY A 127 N ASP A 21  ? N ASP A 21  
AA2 1  2  N LEU B 18  ? N LEU B 18  O VAL B 29  ? O VAL B 29  
AA2 2  3  N SER B 30  ? N SER B 30  O ILE B 47  ? O ILE B 47  
AA2 3  4  N PHE B 46  ? N PHE B 46  O MET B 216 ? O MET B 218 
AA2 4  5  O THR B 223 ? O THR B 225 N PHE B 200 ? N PHE B 202 
AA2 5  6  O HIS B 197 ? O HIS B 199 N ILE B 150 ? N ILE B 152 
AA2 6  7  N ASP B 153 ? N ASP B 155 O GLY B 158 ? O GLY B 160 
AA2 7  8  N HIS B 167 ? N HIS B 169 O GLN B 175 ? O GLN B 177 
AA2 8  9  O THR B 184 ? O THR B 186 N VAL B 91  ? N VAL B 93  
AA2 9  10 N ILE B 96  ? N ILE B 98  O TYR B 104 ? O TYR B 106 
AA2 10 11 N LYS B 111 ? N LYS B 113 O VAL B 118 ? O VAL B 120 
AA2 11 12 O GLY B 125 ? O GLY B 127 N ASP B 21  ? N ASP B 21  
AA3 1  2  N VAL C 16  ? N VAL C 16  O GLY C 31  ? O GLY C 31  
AA3 2  3  N ASP C 36  ? N ASP C 36  O LYS C 41  ? O LYS C 41  
AA3 3  4  N PHE C 46  ? N PHE C 46  O MET C 216 ? O MET C 218 
AA3 4  5  O THR C 223 ? O THR C 225 N PHE C 200 ? N PHE C 202 
AA3 5  6  O HIS C 197 ? O HIS C 199 N ILE C 150 ? N ILE C 152 
AA3 6  7  N ASP C 153 ? N ASP C 155 O GLY C 158 ? O GLY C 160 
AA3 7  8  N HIS C 167 ? N HIS C 169 O GLN C 175 ? O GLN C 177 
AA3 8  9  O THR C 184 ? O THR C 186 N VAL C 91  ? N VAL C 93  
AA3 9  10 N TYR C 90  ? N TYR C 92  O VAL C 110 ? O VAL C 112 
AA3 10 11 N LYS C 111 ? N LYS C 113 O VAL C 118 ? O VAL C 120 
AA3 11 12 O ILE C 121 ? O ILE C 123 N GLU C 17  ? N GLU C 17  
AA4 1  2  N LEU D 18  ? N LEU D 18  O VAL D 29  ? O VAL D 29  
AA4 2  3  N ASP D 36  ? N ASP D 36  O LYS D 41  ? O LYS D 41  
AA4 3  4  N LEU D 44  ? N LEU D 44  O LEU D 218 ? O LEU D 220 
AA4 4  5  O THR D 223 ? O THR D 225 N PHE D 200 ? N PHE D 202 
AA4 5  6  O HIS D 197 ? O HIS D 199 N ILE D 150 ? N ILE D 152 
AA4 6  7  N ASP D 153 ? N ASP D 155 O GLY D 158 ? O GLY D 160 
AA4 7  8  N HIS D 167 ? N HIS D 169 O GLN D 175 ? O GLN D 177 
AA4 8  9  O THR D 184 ? O THR D 186 N VAL D 91  ? N VAL D 93  
AA4 9  10 N GLN D 92  ? N GLN D 94  O ALA D 108 ? O ALA D 110 
AA4 10 11 N LYS D 111 ? N LYS D 113 O VAL D 118 ? O VAL D 120 
AA4 11 12 O GLY D 125 ? O GLY D 127 N ASP D 21  ? N ASP D 21  
# 
_pdbx_entry_details.entry_id                   8JL2 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CB 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            ASP 
_pdbx_validate_rmsd_bond.auth_seq_id_1             173 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            CG 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            ASP 
_pdbx_validate_rmsd_bond.auth_seq_id_2             173 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.363 
_pdbx_validate_rmsd_bond.bond_target_value         1.513 
_pdbx_validate_rmsd_bond.bond_deviation            -0.150 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.021 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CB A MET 78  ? ? CA A MET 78  ? ? C   A MET 78  ? ? 97.06  110.40 -13.34 2.00 N 
2 1 CB A ASP 173 ? ? CG A ASP 173 ? ? OD1 A ASP 173 ? ? 110.78 118.30 -7.52  0.90 N 
3 1 N  D LYS 79  ? ? CA D LYS 79  ? ? C   D LYS 79  ? ? 132.82 111.00 21.82  2.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE A 136 ? ? -95.69  -65.84  
2  1 ASP A 173 ? ? -108.39 42.40   
3  1 LYS B 79  ? ? -73.84  45.19   
4  1 ARG B 80  ? ? -147.11 -13.38  
5  1 ASP B 103 ? ? -150.32 -158.66 
6  1 ILE B 136 ? ? -94.08  -64.57  
7  1 ILE C 136 ? ? -93.63  -66.41  
8  1 LYS D 79  ? ? -68.19  14.66   
9  1 ASP D 82  ? ? -49.62  108.04  
10 1 ILE D 136 ? ? -91.67  -68.16  
11 1 ASN D 144 ? ? -162.97 -169.91 
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 MET A 78  ? ? LYS A 79  ? ? 147.40 
2 1 PRO B 196 ? ? ASP B 197 ? ? 149.33 
# 
loop_
_pdbx_struct_mod_residue.id 
_pdbx_struct_mod_residue.label_asym_id 
_pdbx_struct_mod_residue.label_comp_id 
_pdbx_struct_mod_residue.label_seq_id 
_pdbx_struct_mod_residue.auth_asym_id 
_pdbx_struct_mod_residue.auth_comp_id 
_pdbx_struct_mod_residue.auth_seq_id 
_pdbx_struct_mod_residue.PDB_ins_code 
_pdbx_struct_mod_residue.parent_comp_id 
_pdbx_struct_mod_residue.details 
1  A CRO 65 A CRO 66 ? SER chromophore 
2  A CRO 65 A CRO 66 ? TYR chromophore 
3  A CRO 65 A CRO 66 ? GLY chromophore 
4  B CRO 65 B CRO 66 ? SER chromophore 
5  B CRO 65 B CRO 66 ? TYR chromophore 
6  B CRO 65 B CRO 66 ? GLY chromophore 
7  C CRO 65 C CRO 66 ? SER chromophore 
8  C CRO 65 C CRO 66 ? TYR chromophore 
9  C CRO 65 C CRO 66 ? GLY chromophore 
10 D CRO 65 D CRO 66 ? SER chromophore 
11 D CRO 65 D CRO 66 ? TYR chromophore 
12 D CRO 65 D CRO 66 ? GLY chromophore 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? B HOH 511 ? 5.81 . 
2 1 O ? B HOH 512 ? 5.92 . 
3 1 O ? B HOH 513 ? 6.87 . 
4 1 O ? D HOH 505 ? 5.81 . 
5 1 O ? D HOH 506 ? 6.85 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A SER 2   ? A SER 2   
3  1 Y 1 A THR 230 ? A THR 228 
4  1 Y 1 A HIS 231 ? A HIS 229 
5  1 Y 1 A GLY 232 ? A GLY 230 
6  1 Y 1 A MET 233 ? A MET 231 
7  1 Y 1 A ASP 234 ? A ASP 232 
8  1 Y 1 A GLU 235 ? A GLU 233 
9  1 Y 1 A LEU 236 ? A LEU 234 
10 1 Y 1 A TYR 237 ? A TYR 235 
11 1 Y 1 A LYS 238 ? A LYS 236 
12 1 Y 1 B MET 1   ? B MET 1   
13 1 Y 1 B SER 2   ? B SER 2   
14 1 Y 1 B THR 230 ? B THR 228 
15 1 Y 1 B HIS 231 ? B HIS 229 
16 1 Y 1 B GLY 232 ? B GLY 230 
17 1 Y 1 B MET 233 ? B MET 231 
18 1 Y 1 B ASP 234 ? B ASP 232 
19 1 Y 1 B GLU 235 ? B GLU 233 
20 1 Y 1 B LEU 236 ? B LEU 234 
21 1 Y 1 B TYR 237 ? B TYR 235 
22 1 Y 1 B LYS 238 ? B LYS 236 
23 1 Y 1 C MET 1   ? C MET 1   
24 1 Y 1 C SER 2   ? C SER 2   
25 1 Y 1 C THR 230 ? C THR 228 
26 1 Y 1 C HIS 231 ? C HIS 229 
27 1 Y 1 C GLY 232 ? C GLY 230 
28 1 Y 1 C MET 233 ? C MET 231 
29 1 Y 1 C ASP 234 ? C ASP 232 
30 1 Y 1 C GLU 235 ? C GLU 233 
31 1 Y 1 C LEU 236 ? C LEU 234 
32 1 Y 1 C TYR 237 ? C TYR 235 
33 1 Y 1 C LYS 238 ? C LYS 236 
34 1 Y 1 D MET 1   ? D MET 1   
35 1 Y 1 D SER 2   ? D SER 2   
36 1 Y 1 D THR 230 ? D THR 228 
37 1 Y 1 D HIS 231 ? D HIS 229 
38 1 Y 1 D GLY 232 ? D GLY 230 
39 1 Y 1 D MET 233 ? D MET 231 
40 1 Y 1 D ASP 234 ? D ASP 232 
41 1 Y 1 D GLU 235 ? D GLU 233 
42 1 Y 1 D LEU 236 ? D LEU 234 
43 1 Y 1 D TYR 237 ? D TYR 235 
44 1 Y 1 D LYS 238 ? D LYS 236 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CRO N1   N N N 74  
CRO CA1  C N R 75  
CRO CB1  C N R 76  
CRO CG1  C N N 77  
CRO OG1  O N N 78  
CRO C1   C N N 79  
CRO N2   N N N 80  
CRO N3   N N N 81  
CRO C2   C N N 82  
CRO O2   O N N 83  
CRO CA2  C N N 84  
CRO CA3  C N N 85  
CRO C3   C N N 86  
CRO O3   O N N 87  
CRO CB2  C N N 88  
CRO CG2  C Y N 89  
CRO CD1  C Y N 90  
CRO CD2  C Y N 91  
CRO CE1  C Y N 92  
CRO CE2  C Y N 93  
CRO CZ   C Y N 94  
CRO OH   O N N 95  
CRO OXT  O N N 96  
CRO H    H N N 97  
CRO H2   H N N 98  
CRO HA1  H N N 99  
CRO HB1  H N N 100 
CRO HG11 H N N 101 
CRO HG12 H N N 102 
CRO HG13 H N N 103 
CRO HOG1 H N N 104 
CRO HA31 H N N 105 
CRO HA32 H N N 106 
CRO HXT  H N N 107 
CRO HB2  H N N 108 
CRO HD1  H N N 109 
CRO HD2  H N N 110 
CRO HE1  H N N 111 
CRO HE2  H N N 112 
CRO HOH  H N N 113 
CYS N    N N N 114 
CYS CA   C N R 115 
CYS C    C N N 116 
CYS O    O N N 117 
CYS CB   C N N 118 
CYS SG   S N N 119 
CYS OXT  O N N 120 
CYS H    H N N 121 
CYS H2   H N N 122 
CYS HA   H N N 123 
CYS HB2  H N N 124 
CYS HB3  H N N 125 
CYS HG   H N N 126 
CYS HXT  H N N 127 
GLN N    N N N 128 
GLN CA   C N S 129 
GLN C    C N N 130 
GLN O    O N N 131 
GLN CB   C N N 132 
GLN CG   C N N 133 
GLN CD   C N N 134 
GLN OE1  O N N 135 
GLN NE2  N N N 136 
GLN OXT  O N N 137 
GLN H    H N N 138 
GLN H2   H N N 139 
GLN HA   H N N 140 
GLN HB2  H N N 141 
GLN HB3  H N N 142 
GLN HG2  H N N 143 
GLN HG3  H N N 144 
GLN HE21 H N N 145 
GLN HE22 H N N 146 
GLN HXT  H N N 147 
GLU N    N N N 148 
GLU CA   C N S 149 
GLU C    C N N 150 
GLU O    O N N 151 
GLU CB   C N N 152 
GLU CG   C N N 153 
GLU CD   C N N 154 
GLU OE1  O N N 155 
GLU OE2  O N N 156 
GLU OXT  O N N 157 
GLU H    H N N 158 
GLU H2   H N N 159 
GLU HA   H N N 160 
GLU HB2  H N N 161 
GLU HB3  H N N 162 
GLU HG2  H N N 163 
GLU HG3  H N N 164 
GLU HE2  H N N 165 
GLU HXT  H N N 166 
GLY N    N N N 167 
GLY CA   C N N 168 
GLY C    C N N 169 
GLY O    O N N 170 
GLY OXT  O N N 171 
GLY H    H N N 172 
GLY H2   H N N 173 
GLY HA2  H N N 174 
GLY HA3  H N N 175 
GLY HXT  H N N 176 
HIS N    N N N 177 
HIS CA   C N S 178 
HIS C    C N N 179 
HIS O    O N N 180 
HIS CB   C N N 181 
HIS CG   C Y N 182 
HIS ND1  N Y N 183 
HIS CD2  C Y N 184 
HIS CE1  C Y N 185 
HIS NE2  N Y N 186 
HIS OXT  O N N 187 
HIS H    H N N 188 
HIS H2   H N N 189 
HIS HA   H N N 190 
HIS HB2  H N N 191 
HIS HB3  H N N 192 
HIS HD1  H N N 193 
HIS HD2  H N N 194 
HIS HE1  H N N 195 
HIS HE2  H N N 196 
HIS HXT  H N N 197 
HOH O    O N N 198 
HOH H1   H N N 199 
HOH H2   H N N 200 
ILE N    N N N 201 
ILE CA   C N S 202 
ILE C    C N N 203 
ILE O    O N N 204 
ILE CB   C N S 205 
ILE CG1  C N N 206 
ILE CG2  C N N 207 
ILE CD1  C N N 208 
ILE OXT  O N N 209 
ILE H    H N N 210 
ILE H2   H N N 211 
ILE HA   H N N 212 
ILE HB   H N N 213 
ILE HG12 H N N 214 
ILE HG13 H N N 215 
ILE HG21 H N N 216 
ILE HG22 H N N 217 
ILE HG23 H N N 218 
ILE HD11 H N N 219 
ILE HD12 H N N 220 
ILE HD13 H N N 221 
ILE HXT  H N N 222 
LEU N    N N N 223 
LEU CA   C N S 224 
LEU C    C N N 225 
LEU O    O N N 226 
LEU CB   C N N 227 
LEU CG   C N N 228 
LEU CD1  C N N 229 
LEU CD2  C N N 230 
LEU OXT  O N N 231 
LEU H    H N N 232 
LEU H2   H N N 233 
LEU HA   H N N 234 
LEU HB2  H N N 235 
LEU HB3  H N N 236 
LEU HG   H N N 237 
LEU HD11 H N N 238 
LEU HD12 H N N 239 
LEU HD13 H N N 240 
LEU HD21 H N N 241 
LEU HD22 H N N 242 
LEU HD23 H N N 243 
LEU HXT  H N N 244 
LYS N    N N N 245 
LYS CA   C N S 246 
LYS C    C N N 247 
LYS O    O N N 248 
LYS CB   C N N 249 
LYS CG   C N N 250 
LYS CD   C N N 251 
LYS CE   C N N 252 
LYS NZ   N N N 253 
LYS OXT  O N N 254 
LYS H    H N N 255 
LYS H2   H N N 256 
LYS HA   H N N 257 
LYS HB2  H N N 258 
LYS HB3  H N N 259 
LYS HG2  H N N 260 
LYS HG3  H N N 261 
LYS HD2  H N N 262 
LYS HD3  H N N 263 
LYS HE2  H N N 264 
LYS HE3  H N N 265 
LYS HZ1  H N N 266 
LYS HZ2  H N N 267 
LYS HZ3  H N N 268 
LYS HXT  H N N 269 
MET N    N N N 270 
MET CA   C N S 271 
MET C    C N N 272 
MET O    O N N 273 
MET CB   C N N 274 
MET CG   C N N 275 
MET SD   S N N 276 
MET CE   C N N 277 
MET OXT  O N N 278 
MET H    H N N 279 
MET H2   H N N 280 
MET HA   H N N 281 
MET HB2  H N N 282 
MET HB3  H N N 283 
MET HG2  H N N 284 
MET HG3  H N N 285 
MET HE1  H N N 286 
MET HE2  H N N 287 
MET HE3  H N N 288 
MET HXT  H N N 289 
PHE N    N N N 290 
PHE CA   C N S 291 
PHE C    C N N 292 
PHE O    O N N 293 
PHE CB   C N N 294 
PHE CG   C Y N 295 
PHE CD1  C Y N 296 
PHE CD2  C Y N 297 
PHE CE1  C Y N 298 
PHE CE2  C Y N 299 
PHE CZ   C Y N 300 
PHE OXT  O N N 301 
PHE H    H N N 302 
PHE H2   H N N 303 
PHE HA   H N N 304 
PHE HB2  H N N 305 
PHE HB3  H N N 306 
PHE HD1  H N N 307 
PHE HD2  H N N 308 
PHE HE1  H N N 309 
PHE HE2  H N N 310 
PHE HZ   H N N 311 
PHE HXT  H N N 312 
PRO N    N N N 313 
PRO CA   C N S 314 
PRO C    C N N 315 
PRO O    O N N 316 
PRO CB   C N N 317 
PRO CG   C N N 318 
PRO CD   C N N 319 
PRO OXT  O N N 320 
PRO H    H N N 321 
PRO HA   H N N 322 
PRO HB2  H N N 323 
PRO HB3  H N N 324 
PRO HG2  H N N 325 
PRO HG3  H N N 326 
PRO HD2  H N N 327 
PRO HD3  H N N 328 
PRO HXT  H N N 329 
SER N    N N N 330 
SER CA   C N S 331 
SER C    C N N 332 
SER O    O N N 333 
SER CB   C N N 334 
SER OG   O N N 335 
SER OXT  O N N 336 
SER H    H N N 337 
SER H2   H N N 338 
SER HA   H N N 339 
SER HB2  H N N 340 
SER HB3  H N N 341 
SER HG   H N N 342 
SER HXT  H N N 343 
THR N    N N N 344 
THR CA   C N S 345 
THR C    C N N 346 
THR O    O N N 347 
THR CB   C N R 348 
THR OG1  O N N 349 
THR CG2  C N N 350 
THR OXT  O N N 351 
THR H    H N N 352 
THR H2   H N N 353 
THR HA   H N N 354 
THR HB   H N N 355 
THR HG1  H N N 356 
THR HG21 H N N 357 
THR HG22 H N N 358 
THR HG23 H N N 359 
THR HXT  H N N 360 
TRP N    N N N 361 
TRP CA   C N S 362 
TRP C    C N N 363 
TRP O    O N N 364 
TRP CB   C N N 365 
TRP CG   C Y N 366 
TRP CD1  C Y N 367 
TRP CD2  C Y N 368 
TRP NE1  N Y N 369 
TRP CE2  C Y N 370 
TRP CE3  C Y N 371 
TRP CZ2  C Y N 372 
TRP CZ3  C Y N 373 
TRP CH2  C Y N 374 
TRP OXT  O N N 375 
TRP H    H N N 376 
TRP H2   H N N 377 
TRP HA   H N N 378 
TRP HB2  H N N 379 
TRP HB3  H N N 380 
TRP HD1  H N N 381 
TRP HE1  H N N 382 
TRP HE3  H N N 383 
TRP HZ2  H N N 384 
TRP HZ3  H N N 385 
TRP HH2  H N N 386 
TRP HXT  H N N 387 
TYR N    N N N 388 
TYR CA   C N S 389 
TYR C    C N N 390 
TYR O    O N N 391 
TYR CB   C N N 392 
TYR CG   C Y N 393 
TYR CD1  C Y N 394 
TYR CD2  C Y N 395 
TYR CE1  C Y N 396 
TYR CE2  C Y N 397 
TYR CZ   C Y N 398 
TYR OH   O N N 399 
TYR OXT  O N N 400 
TYR H    H N N 401 
TYR H2   H N N 402 
TYR HA   H N N 403 
TYR HB2  H N N 404 
TYR HB3  H N N 405 
TYR HD1  H N N 406 
TYR HD2  H N N 407 
TYR HE1  H N N 408 
TYR HE2  H N N 409 
TYR HH   H N N 410 
TYR HXT  H N N 411 
VAL N    N N N 412 
VAL CA   C N S 413 
VAL C    C N N 414 
VAL O    O N N 415 
VAL CB   C N N 416 
VAL CG1  C N N 417 
VAL CG2  C N N 418 
VAL OXT  O N N 419 
VAL H    H N N 420 
VAL H2   H N N 421 
VAL HA   H N N 422 
VAL HB   H N N 423 
VAL HG11 H N N 424 
VAL HG12 H N N 425 
VAL HG13 H N N 426 
VAL HG21 H N N 427 
VAL HG22 H N N 428 
VAL HG23 H N N 429 
VAL HXT  H N N 430 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CRO CG1 CB1  sing N N 70  
CRO OG1 CB1  sing N N 71  
CRO CB1 CA1  sing N N 72  
CRO N1  CA1  sing N N 73  
CRO OH  CZ   sing N N 74  
CRO CE1 CZ   doub Y N 75  
CRO CE1 CD1  sing Y N 76  
CRO CA1 C1   sing N N 77  
CRO CZ  CE2  sing Y N 78  
CRO CD1 CG2  doub Y N 79  
CRO N2  C1   doub N N 80  
CRO N2  CA2  sing N N 81  
CRO C1  N3   sing N N 82  
CRO CE2 CD2  doub Y N 83  
CRO CG2 CD2  sing Y N 84  
CRO CG2 CB2  sing N N 85  
CRO N3  CA3  sing N N 86  
CRO N3  C2   sing N N 87  
CRO CA2 CB2  doub N Z 88  
CRO CA2 C2   sing N N 89  
CRO CA3 C3   sing N N 90  
CRO OXT C3   sing N N 91  
CRO C3  O3   doub N N 92  
CRO C2  O2   doub N N 93  
CRO N1  H    sing N N 94  
CRO N1  H2   sing N N 95  
CRO CA1 HA1  sing N N 96  
CRO CB1 HB1  sing N N 97  
CRO CG1 HG11 sing N N 98  
CRO CG1 HG12 sing N N 99  
CRO CG1 HG13 sing N N 100 
CRO OG1 HOG1 sing N N 101 
CRO CA3 HA31 sing N N 102 
CRO CA3 HA32 sing N N 103 
CRO OXT HXT  sing N N 104 
CRO CB2 HB2  sing N N 105 
CRO CD1 HD1  sing N N 106 
CRO CD2 HD2  sing N N 107 
CRO CE1 HE1  sing N N 108 
CRO CE2 HE2  sing N N 109 
CRO OH  HOH  sing N N 110 
CYS N   CA   sing N N 111 
CYS N   H    sing N N 112 
CYS N   H2   sing N N 113 
CYS CA  C    sing N N 114 
CYS CA  CB   sing N N 115 
CYS CA  HA   sing N N 116 
CYS C   O    doub N N 117 
CYS C   OXT  sing N N 118 
CYS CB  SG   sing N N 119 
CYS CB  HB2  sing N N 120 
CYS CB  HB3  sing N N 121 
CYS SG  HG   sing N N 122 
CYS OXT HXT  sing N N 123 
GLN N   CA   sing N N 124 
GLN N   H    sing N N 125 
GLN N   H2   sing N N 126 
GLN CA  C    sing N N 127 
GLN CA  CB   sing N N 128 
GLN CA  HA   sing N N 129 
GLN C   O    doub N N 130 
GLN C   OXT  sing N N 131 
GLN CB  CG   sing N N 132 
GLN CB  HB2  sing N N 133 
GLN CB  HB3  sing N N 134 
GLN CG  CD   sing N N 135 
GLN CG  HG2  sing N N 136 
GLN CG  HG3  sing N N 137 
GLN CD  OE1  doub N N 138 
GLN CD  NE2  sing N N 139 
GLN NE2 HE21 sing N N 140 
GLN NE2 HE22 sing N N 141 
GLN OXT HXT  sing N N 142 
GLU N   CA   sing N N 143 
GLU N   H    sing N N 144 
GLU N   H2   sing N N 145 
GLU CA  C    sing N N 146 
GLU CA  CB   sing N N 147 
GLU CA  HA   sing N N 148 
GLU C   O    doub N N 149 
GLU C   OXT  sing N N 150 
GLU CB  CG   sing N N 151 
GLU CB  HB2  sing N N 152 
GLU CB  HB3  sing N N 153 
GLU CG  CD   sing N N 154 
GLU CG  HG2  sing N N 155 
GLU CG  HG3  sing N N 156 
GLU CD  OE1  doub N N 157 
GLU CD  OE2  sing N N 158 
GLU OE2 HE2  sing N N 159 
GLU OXT HXT  sing N N 160 
GLY N   CA   sing N N 161 
GLY N   H    sing N N 162 
GLY N   H2   sing N N 163 
GLY CA  C    sing N N 164 
GLY CA  HA2  sing N N 165 
GLY CA  HA3  sing N N 166 
GLY C   O    doub N N 167 
GLY C   OXT  sing N N 168 
GLY OXT HXT  sing N N 169 
HIS N   CA   sing N N 170 
HIS N   H    sing N N 171 
HIS N   H2   sing N N 172 
HIS CA  C    sing N N 173 
HIS CA  CB   sing N N 174 
HIS CA  HA   sing N N 175 
HIS C   O    doub N N 176 
HIS C   OXT  sing N N 177 
HIS CB  CG   sing N N 178 
HIS CB  HB2  sing N N 179 
HIS CB  HB3  sing N N 180 
HIS CG  ND1  sing Y N 181 
HIS CG  CD2  doub Y N 182 
HIS ND1 CE1  doub Y N 183 
HIS ND1 HD1  sing N N 184 
HIS CD2 NE2  sing Y N 185 
HIS CD2 HD2  sing N N 186 
HIS CE1 NE2  sing Y N 187 
HIS CE1 HE1  sing N N 188 
HIS NE2 HE2  sing N N 189 
HIS OXT HXT  sing N N 190 
HOH O   H1   sing N N 191 
HOH O   H2   sing N N 192 
ILE N   CA   sing N N 193 
ILE N   H    sing N N 194 
ILE N   H2   sing N N 195 
ILE CA  C    sing N N 196 
ILE CA  CB   sing N N 197 
ILE CA  HA   sing N N 198 
ILE C   O    doub N N 199 
ILE C   OXT  sing N N 200 
ILE CB  CG1  sing N N 201 
ILE CB  CG2  sing N N 202 
ILE CB  HB   sing N N 203 
ILE CG1 CD1  sing N N 204 
ILE CG1 HG12 sing N N 205 
ILE CG1 HG13 sing N N 206 
ILE CG2 HG21 sing N N 207 
ILE CG2 HG22 sing N N 208 
ILE CG2 HG23 sing N N 209 
ILE CD1 HD11 sing N N 210 
ILE CD1 HD12 sing N N 211 
ILE CD1 HD13 sing N N 212 
ILE OXT HXT  sing N N 213 
LEU N   CA   sing N N 214 
LEU N   H    sing N N 215 
LEU N   H2   sing N N 216 
LEU CA  C    sing N N 217 
LEU CA  CB   sing N N 218 
LEU CA  HA   sing N N 219 
LEU C   O    doub N N 220 
LEU C   OXT  sing N N 221 
LEU CB  CG   sing N N 222 
LEU CB  HB2  sing N N 223 
LEU CB  HB3  sing N N 224 
LEU CG  CD1  sing N N 225 
LEU CG  CD2  sing N N 226 
LEU CG  HG   sing N N 227 
LEU CD1 HD11 sing N N 228 
LEU CD1 HD12 sing N N 229 
LEU CD1 HD13 sing N N 230 
LEU CD2 HD21 sing N N 231 
LEU CD2 HD22 sing N N 232 
LEU CD2 HD23 sing N N 233 
LEU OXT HXT  sing N N 234 
LYS N   CA   sing N N 235 
LYS N   H    sing N N 236 
LYS N   H2   sing N N 237 
LYS CA  C    sing N N 238 
LYS CA  CB   sing N N 239 
LYS CA  HA   sing N N 240 
LYS C   O    doub N N 241 
LYS C   OXT  sing N N 242 
LYS CB  CG   sing N N 243 
LYS CB  HB2  sing N N 244 
LYS CB  HB3  sing N N 245 
LYS CG  CD   sing N N 246 
LYS CG  HG2  sing N N 247 
LYS CG  HG3  sing N N 248 
LYS CD  CE   sing N N 249 
LYS CD  HD2  sing N N 250 
LYS CD  HD3  sing N N 251 
LYS CE  NZ   sing N N 252 
LYS CE  HE2  sing N N 253 
LYS CE  HE3  sing N N 254 
LYS NZ  HZ1  sing N N 255 
LYS NZ  HZ2  sing N N 256 
LYS NZ  HZ3  sing N N 257 
LYS OXT HXT  sing N N 258 
MET N   CA   sing N N 259 
MET N   H    sing N N 260 
MET N   H2   sing N N 261 
MET CA  C    sing N N 262 
MET CA  CB   sing N N 263 
MET CA  HA   sing N N 264 
MET C   O    doub N N 265 
MET C   OXT  sing N N 266 
MET CB  CG   sing N N 267 
MET CB  HB2  sing N N 268 
MET CB  HB3  sing N N 269 
MET CG  SD   sing N N 270 
MET CG  HG2  sing N N 271 
MET CG  HG3  sing N N 272 
MET SD  CE   sing N N 273 
MET CE  HE1  sing N N 274 
MET CE  HE2  sing N N 275 
MET CE  HE3  sing N N 276 
MET OXT HXT  sing N N 277 
PHE N   CA   sing N N 278 
PHE N   H    sing N N 279 
PHE N   H2   sing N N 280 
PHE CA  C    sing N N 281 
PHE CA  CB   sing N N 282 
PHE CA  HA   sing N N 283 
PHE C   O    doub N N 284 
PHE C   OXT  sing N N 285 
PHE CB  CG   sing N N 286 
PHE CB  HB2  sing N N 287 
PHE CB  HB3  sing N N 288 
PHE CG  CD1  doub Y N 289 
PHE CG  CD2  sing Y N 290 
PHE CD1 CE1  sing Y N 291 
PHE CD1 HD1  sing N N 292 
PHE CD2 CE2  doub Y N 293 
PHE CD2 HD2  sing N N 294 
PHE CE1 CZ   doub Y N 295 
PHE CE1 HE1  sing N N 296 
PHE CE2 CZ   sing Y N 297 
PHE CE2 HE2  sing N N 298 
PHE CZ  HZ   sing N N 299 
PHE OXT HXT  sing N N 300 
PRO N   CA   sing N N 301 
PRO N   CD   sing N N 302 
PRO N   H    sing N N 303 
PRO CA  C    sing N N 304 
PRO CA  CB   sing N N 305 
PRO CA  HA   sing N N 306 
PRO C   O    doub N N 307 
PRO C   OXT  sing N N 308 
PRO CB  CG   sing N N 309 
PRO CB  HB2  sing N N 310 
PRO CB  HB3  sing N N 311 
PRO CG  CD   sing N N 312 
PRO CG  HG2  sing N N 313 
PRO CG  HG3  sing N N 314 
PRO CD  HD2  sing N N 315 
PRO CD  HD3  sing N N 316 
PRO OXT HXT  sing N N 317 
SER N   CA   sing N N 318 
SER N   H    sing N N 319 
SER N   H2   sing N N 320 
SER CA  C    sing N N 321 
SER CA  CB   sing N N 322 
SER CA  HA   sing N N 323 
SER C   O    doub N N 324 
SER C   OXT  sing N N 325 
SER CB  OG   sing N N 326 
SER CB  HB2  sing N N 327 
SER CB  HB3  sing N N 328 
SER OG  HG   sing N N 329 
SER OXT HXT  sing N N 330 
THR N   CA   sing N N 331 
THR N   H    sing N N 332 
THR N   H2   sing N N 333 
THR CA  C    sing N N 334 
THR CA  CB   sing N N 335 
THR CA  HA   sing N N 336 
THR C   O    doub N N 337 
THR C   OXT  sing N N 338 
THR CB  OG1  sing N N 339 
THR CB  CG2  sing N N 340 
THR CB  HB   sing N N 341 
THR OG1 HG1  sing N N 342 
THR CG2 HG21 sing N N 343 
THR CG2 HG22 sing N N 344 
THR CG2 HG23 sing N N 345 
THR OXT HXT  sing N N 346 
TRP N   CA   sing N N 347 
TRP N   H    sing N N 348 
TRP N   H2   sing N N 349 
TRP CA  C    sing N N 350 
TRP CA  CB   sing N N 351 
TRP CA  HA   sing N N 352 
TRP C   O    doub N N 353 
TRP C   OXT  sing N N 354 
TRP CB  CG   sing N N 355 
TRP CB  HB2  sing N N 356 
TRP CB  HB3  sing N N 357 
TRP CG  CD1  doub Y N 358 
TRP CG  CD2  sing Y N 359 
TRP CD1 NE1  sing Y N 360 
TRP CD1 HD1  sing N N 361 
TRP CD2 CE2  doub Y N 362 
TRP CD2 CE3  sing Y N 363 
TRP NE1 CE2  sing Y N 364 
TRP NE1 HE1  sing N N 365 
TRP CE2 CZ2  sing Y N 366 
TRP CE3 CZ3  doub Y N 367 
TRP CE3 HE3  sing N N 368 
TRP CZ2 CH2  doub Y N 369 
TRP CZ2 HZ2  sing N N 370 
TRP CZ3 CH2  sing Y N 371 
TRP CZ3 HZ3  sing N N 372 
TRP CH2 HH2  sing N N 373 
TRP OXT HXT  sing N N 374 
TYR N   CA   sing N N 375 
TYR N   H    sing N N 376 
TYR N   H2   sing N N 377 
TYR CA  C    sing N N 378 
TYR CA  CB   sing N N 379 
TYR CA  HA   sing N N 380 
TYR C   O    doub N N 381 
TYR C   OXT  sing N N 382 
TYR CB  CG   sing N N 383 
TYR CB  HB2  sing N N 384 
TYR CB  HB3  sing N N 385 
TYR CG  CD1  doub Y N 386 
TYR CG  CD2  sing Y N 387 
TYR CD1 CE1  sing Y N 388 
TYR CD1 HD1  sing N N 389 
TYR CD2 CE2  doub Y N 390 
TYR CD2 HD2  sing N N 391 
TYR CE1 CZ   doub Y N 392 
TYR CE1 HE1  sing N N 393 
TYR CE2 CZ   sing Y N 394 
TYR CE2 HE2  sing N N 395 
TYR CZ  OH   sing N N 396 
TYR OH  HH   sing N N 397 
TYR OXT HXT  sing N N 398 
VAL N   CA   sing N N 399 
VAL N   H    sing N N 400 
VAL N   H2   sing N N 401 
VAL CA  C    sing N N 402 
VAL CA  CB   sing N N 403 
VAL CA  HA   sing N N 404 
VAL C   O    doub N N 405 
VAL C   OXT  sing N N 406 
VAL CB  CG1  sing N N 407 
VAL CB  CG2  sing N N 408 
VAL CB  HB   sing N N 409 
VAL CG1 HG11 sing N N 410 
VAL CG1 HG12 sing N N 411 
VAL CG1 HG13 sing N N 412 
VAL CG2 HG21 sing N N 413 
VAL CG2 HG22 sing N N 414 
VAL CG2 HG23 sing N N 415 
VAL OXT HXT  sing N N 416 
# 
_pdbx_audit_support.funding_organization   'National Research Foundation (NRF, Korea)' 
_pdbx_audit_support.country                'Korea, Republic Of' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5WWK 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8JL2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   0.013098 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012415 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005562 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LYS A 1 3   ? -24.468 44.526  -12.903 1.00 39.27 ? 3   LYS A N   1 
ATOM   2    C CA  . LYS A 1 3   ? -25.869 44.158  -12.802 1.00 35.94 ? 3   LYS A CA  1 
ATOM   3    C C   . LYS A 1 3   ? -26.174 42.828  -13.488 1.00 33.93 ? 3   LYS A C   1 
ATOM   4    O O   . LYS A 1 3   ? -25.610 42.487  -14.530 1.00 28.62 ? 3   LYS A O   1 
ATOM   5    C CB  . LYS A 1 3   ? -26.767 45.253  -13.398 1.00 38.29 ? 3   LYS A CB  1 
ATOM   6    C CG  . LYS A 1 3   ? -27.010 46.443  -12.491 1.00 38.17 ? 3   LYS A CG  1 
ATOM   7    C CD  . LYS A 1 3   ? -27.964 47.457  -13.133 1.00 43.00 ? 3   LYS A CD  1 
ATOM   8    C CE  . LYS A 1 3   ? -27.628 47.707  -14.601 1.00 41.15 ? 3   LYS A CE  1 
ATOM   9    N NZ  . LYS A 1 3   ? -26.316 48.399  -14.769 1.00 42.69 ? 3   LYS A NZ  1 
ATOM   10   N N   . GLY A 1 4   ? -27.079 42.067  -12.877 1.00 32.10 ? 4   GLY A N   1 
ATOM   11   C CA  . GLY A 1 4   ? -27.667 40.950  -13.583 1.00 27.94 ? 4   GLY A CA  1 
ATOM   12   C C   . GLY A 1 4   ? -28.558 41.364  -14.730 1.00 25.38 ? 4   GLY A C   1 
ATOM   13   O O   . GLY A 1 4   ? -28.818 40.548  -15.618 1.00 24.51 ? 4   GLY A O   1 
ATOM   14   N N   . GLU A 1 5   ? -29.027 42.621  -14.741 1.00 27.20 ? 5   GLU A N   1 
ATOM   15   C CA  . GLU A 1 5   ? -29.843 43.081  -15.862 1.00 29.28 ? 5   GLU A CA  1 
ATOM   16   C C   . GLU A 1 5   ? -29.050 43.129  -17.158 1.00 29.26 ? 5   GLU A C   1 
ATOM   17   O O   . GLU A 1 5   ? -29.610 42.880  -18.232 1.00 26.49 ? 5   GLU A O   1 
ATOM   18   C CB  . GLU A 1 5   ? -30.463 44.448  -15.567 1.00 31.15 ? 5   GLU A CB  1 
ATOM   19   C CG  . GLU A 1 5   ? -31.366 44.456  -14.349 1.00 35.60 ? 5   GLU A CG  1 
ATOM   20   C CD  . GLU A 1 5   ? -31.819 45.848  -13.953 1.00 45.45 ? 5   GLU A CD  1 
ATOM   21   O OE1 . GLU A 1 5   ? -32.724 45.946  -13.085 1.00 39.61 ? 5   GLU A OE1 1 
ATOM   22   O OE2 . GLU A 1 5   ? -31.280 46.831  -14.515 1.00 47.64 ? 5   GLU A OE2 1 
ATOM   23   N N   . GLU A 1 6   ? -27.749 43.422  -17.083 1.00 28.42 ? 6   GLU A N   1 
ATOM   24   C CA  . GLU A 1 6   ? -26.931 43.389  -18.287 1.00 27.21 ? 6   GLU A CA  1 
ATOM   25   C C   . GLU A 1 6   ? -26.853 41.998  -18.896 1.00 27.61 ? 6   GLU A C   1 
ATOM   26   O O   . GLU A 1 6   ? -26.585 41.873  -20.096 1.00 27.41 ? 6   GLU A O   1 
ATOM   27   C CB  . GLU A 1 6   ? -25.528 43.905  -17.983 1.00 35.71 ? 6   GLU A CB  1 
ATOM   28   C CG  . GLU A 1 6   ? -24.950 44.723  -19.119 1.00 43.53 ? 6   GLU A CG  1 
ATOM   29   C CD  . GLU A 1 6   ? -25.310 46.197  -19.013 1.00 49.24 ? 6   GLU A CD  1 
ATOM   30   O OE1 . GLU A 1 6   ? -26.351 46.600  -19.585 1.00 52.14 ? 6   GLU A OE1 1 
ATOM   31   O OE2 . GLU A 1 6   ? -24.549 46.954  -18.366 1.00 52.36 ? 6   GLU A OE2 1 
ATOM   32   N N   . LEU A 1 7   ? -27.102 40.951  -18.105 1.00 27.10 ? 7   LEU A N   1 
ATOM   33   C CA  . LEU A 1 7   ? -27.097 39.588  -18.629 1.00 25.70 ? 7   LEU A CA  1 
ATOM   34   C C   . LEU A 1 7   ? -28.272 39.304  -19.554 1.00 26.12 ? 7   LEU A C   1 
ATOM   35   O O   . LEU A 1 7   ? -28.273 38.261  -20.218 1.00 24.53 ? 7   LEU A O   1 
ATOM   36   C CB  . LEU A 1 7   ? -27.107 38.582  -17.473 1.00 24.02 ? 7   LEU A CB  1 
ATOM   37   C CG  . LEU A 1 7   ? -25.847 38.639  -16.620 1.00 24.09 ? 7   LEU A CG  1 
ATOM   38   C CD1 . LEU A 1 7   ? -25.925 37.670  -15.443 1.00 24.50 ? 7   LEU A CD1 1 
ATOM   39   C CD2 . LEU A 1 7   ? -24.619 38.368  -17.486 1.00 29.36 ? 7   LEU A CD2 1 
ATOM   40   N N   . PHE A 1 8   ? -29.265 40.200  -19.625 1.00 27.65 ? 8   PHE A N   1 
ATOM   41   C CA  . PHE A 1 8   ? -30.480 39.949  -20.392 1.00 22.80 ? 8   PHE A CA  1 
ATOM   42   C C   . PHE A 1 8   ? -30.686 40.911  -21.560 1.00 26.10 ? 8   PHE A C   1 
ATOM   43   O O   . PHE A 1 8   ? -31.809 41.024  -22.070 1.00 28.68 ? 8   PHE A O   1 
ATOM   44   C CB  . PHE A 1 8   ? -31.700 39.974  -19.470 1.00 20.18 ? 8   PHE A CB  1 
ATOM   45   C CG  . PHE A 1 8   ? -31.719 38.867  -18.451 1.00 19.29 ? 8   PHE A CG  1 
ATOM   46   C CD1 . PHE A 1 8   ? -31.044 38.985  -17.249 1.00 18.75 ? 8   PHE A CD1 1 
ATOM   47   C CD2 . PHE A 1 8   ? -32.428 37.699  -18.705 1.00 18.37 ? 8   PHE A CD2 1 
ATOM   48   C CE1 . PHE A 1 8   ? -31.078 37.970  -16.327 1.00 19.47 ? 8   PHE A CE1 1 
ATOM   49   C CE2 . PHE A 1 8   ? -32.458 36.674  -17.781 1.00 15.94 ? 8   PHE A CE2 1 
ATOM   50   C CZ  . PHE A 1 8   ? -31.784 36.807  -16.588 1.00 17.90 ? 8   PHE A CZ  1 
ATOM   51   N N   . THR A 1 9   ? -29.632 41.582  -22.035 1.00 27.74 ? 9   THR A N   1 
ATOM   52   C CA  . THR A 1 9   ? -29.813 42.566  -23.108 1.00 28.01 ? 9   THR A CA  1 
ATOM   53   C C   . THR A 1 9   ? -29.993 41.939  -24.489 1.00 30.78 ? 9   THR A C   1 
ATOM   54   O O   . THR A 1 9   ? -30.479 42.620  -25.403 1.00 29.51 ? 9   THR A O   1 
ATOM   55   C CB  . THR A 1 9   ? -28.626 43.531  -23.153 1.00 30.64 ? 9   THR A CB  1 
ATOM   56   O OG1 . THR A 1 9   ? -27.407 42.777  -23.236 1.00 25.43 ? 9   THR A OG1 1 
ATOM   57   C CG2 . THR A 1 9   ? -28.600 44.402  -21.911 1.00 29.98 ? 9   THR A CG2 1 
ATOM   58   N N   . GLY A 1 10  ? -29.610 40.680  -24.677 1.00 22.77 ? 10  GLY A N   1 
ATOM   59   C CA  . GLY A 1 10  ? -29.863 40.018  -25.939 1.00 22.45 ? 10  GLY A CA  1 
ATOM   60   C C   . GLY A 1 10  ? -30.731 38.786  -25.788 1.00 24.01 ? 10  GLY A C   1 
ATOM   61   O O   . GLY A 1 10  ? -31.458 38.652  -24.799 1.00 24.29 ? 10  GLY A O   1 
ATOM   62   N N   . VAL A 1 11  ? -30.646 37.866  -26.742 1.00 20.38 ? 11  VAL A N   1 
ATOM   63   C CA  . VAL A 1 11  ? -31.375 36.605  -26.653 1.00 17.85 ? 11  VAL A CA  1 
ATOM   64   C C   . VAL A 1 11  ? -30.555 35.640  -25.798 1.00 20.93 ? 11  VAL A C   1 
ATOM   65   O O   . VAL A 1 11  ? -29.348 35.484  -26.014 1.00 22.84 ? 11  VAL A O   1 
ATOM   66   C CB  . VAL A 1 11  ? -31.638 36.042  -28.059 1.00 22.35 ? 11  VAL A CB  1 
ATOM   67   C CG1 . VAL A 1 11  ? -32.217 34.625  -28.000 1.00 22.82 ? 11  VAL A CG1 1 
ATOM   68   C CG2 . VAL A 1 11  ? -32.526 36.995  -28.858 1.00 21.64 ? 11  VAL A CG2 1 
ATOM   69   N N   . VAL A 1 12  ? -31.202 35.000  -24.828 1.00 18.20 ? 12  VAL A N   1 
ATOM   70   C CA  . VAL A 1 12  ? -30.547 34.139  -23.845 1.00 19.14 ? 12  VAL A CA  1 
ATOM   71   C C   . VAL A 1 12  ? -31.088 32.727  -23.991 1.00 16.62 ? 12  VAL A C   1 
ATOM   72   O O   . VAL A 1 12  ? -32.303 32.532  -23.915 1.00 16.30 ? 12  VAL A O   1 
ATOM   73   C CB  . VAL A 1 12  ? -30.762 34.634  -22.402 1.00 20.66 ? 12  VAL A CB  1 
ATOM   74   C CG1 . VAL A 1 12  ? -30.158 33.638  -21.392 1.00 17.63 ? 12  VAL A CG1 1 
ATOM   75   C CG2 . VAL A 1 12  ? -30.123 36.017  -22.227 1.00 22.09 ? 12  VAL A CG2 1 
ATOM   76   N N   . PRO A 1 13  ? -30.238 31.705  -24.153 1.00 16.61 ? 13  PRO A N   1 
ATOM   77   C CA  . PRO A 1 13  ? -30.750 30.330  -24.207 1.00 18.47 ? 13  PRO A CA  1 
ATOM   78   C C   . PRO A 1 13  ? -31.313 29.948  -22.851 1.00 15.64 ? 13  PRO A C   1 
ATOM   79   O O   . PRO A 1 13  ? -30.789 30.348  -21.806 1.00 15.45 ? 13  PRO A O   1 
ATOM   80   C CB  . PRO A 1 13  ? -29.519 29.469  -24.534 1.00 17.29 ? 13  PRO A CB  1 
ATOM   81   C CG  . PRO A 1 13  ? -28.356 30.386  -24.614 1.00 20.96 ? 13  PRO A CG  1 
ATOM   82   C CD  . PRO A 1 13  ? -28.794 31.806  -24.427 1.00 18.01 ? 13  PRO A CD  1 
ATOM   83   N N   . ILE A 1 14  ? -32.385 29.161  -22.879 1.00 13.38 ? 14  ILE A N   1 
ATOM   84   C CA  . ILE A 1 14  ? -33.078 28.716  -21.676 1.00 15.13 ? 14  ILE A CA  1 
ATOM   85   C C   . ILE A 1 14  ? -33.047 27.200  -21.645 1.00 14.71 ? 14  ILE A C   1 
ATOM   86   O O   . ILE A 1 14  ? -33.307 26.553  -22.665 1.00 13.36 ? 14  ILE A O   1 
ATOM   87   C CB  . ILE A 1 14  ? -34.535 29.210  -21.633 1.00 15.76 ? 14  ILE A CB  1 
ATOM   88   C CG1 . ILE A 1 14  ? -34.582 30.729  -21.637 1.00 16.26 ? 14  ILE A CG1 1 
ATOM   89   C CG2 . ILE A 1 14  ? -35.234 28.714  -20.360 1.00 13.16 ? 14  ILE A CG2 1 
ATOM   90   C CD1 . ILE A 1 14  ? -36.004 31.273  -21.715 1.00 13.60 ? 14  ILE A CD1 1 
ATOM   91   N N   . LEU A 1 15  ? -32.744 26.640  -20.472 1.00 12.59 ? 15  LEU A N   1 
ATOM   92   C CA  . LEU A 1 15  ? -32.884 25.219  -20.209 1.00 13.99 ? 15  LEU A CA  1 
ATOM   93   C C   . LEU A 1 15  ? -33.812 25.069  -19.012 1.00 11.70 ? 15  LEU A C   1 
ATOM   94   O O   . LEU A 1 15  ? -33.682 25.815  -18.038 1.00 12.61 ? 15  LEU A O   1 
ATOM   95   C CB  . LEU A 1 15  ? -31.516 24.581  -19.897 1.00 13.69 ? 15  LEU A CB  1 
ATOM   96   C CG  . LEU A 1 15  ? -31.498 23.183  -19.273 1.00 14.35 ? 15  LEU A CG  1 
ATOM   97   C CD1 . LEU A 1 15  ? -31.999 22.129  -20.293 1.00 15.70 ? 15  LEU A CD1 1 
ATOM   98   C CD2 . LEU A 1 15  ? -30.106 22.818  -18.737 1.00 14.44 ? 15  LEU A CD2 1 
ATOM   99   N N   . VAL A 1 16  ? -34.739 24.110  -19.075 1.00 11.30 ? 16  VAL A N   1 
ATOM   100  C CA  . VAL A 1 16  ? -35.633 23.773  -17.959 1.00 11.97 ? 16  VAL A CA  1 
ATOM   101  C C   . VAL A 1 16  ? -35.530 22.281  -17.678 1.00 12.40 ? 16  VAL A C   1 
ATOM   102  O O   . VAL A 1 16  ? -35.649 21.460  -18.594 1.00 12.50 ? 16  VAL A O   1 
ATOM   103  C CB  . VAL A 1 16  ? -37.101 24.147  -18.239 1.00 12.48 ? 16  VAL A CB  1 
ATOM   104  C CG1 . VAL A 1 16  ? -37.956 23.913  -16.987 1.00 11.43 ? 16  VAL A CG1 1 
ATOM   105  C CG2 . VAL A 1 16  ? -37.209 25.603  -18.665 1.00 13.68 ? 16  VAL A CG2 1 
ATOM   106  N N   . GLU A 1 17  ? -35.321 21.926  -16.413 1.00 11.55 ? 17  GLU A N   1 
ATOM   107  C CA  . GLU A 1 17  ? -35.300 20.525  -16.012 1.00 11.90 ? 17  GLU A CA  1 
ATOM   108  C C   . GLU A 1 17  ? -36.215 20.364  -14.812 1.00 13.68 ? 17  GLU A C   1 
ATOM   109  O O   . GLU A 1 17  ? -36.003 21.016  -13.784 1.00 14.95 ? 17  GLU A O   1 
ATOM   110  C CB  . GLU A 1 17  ? -33.879 20.055  -15.659 1.00 16.16 ? 17  GLU A CB  1 
ATOM   111  C CG  . GLU A 1 17  ? -32.892 20.045  -16.840 1.00 15.45 ? 17  GLU A CG  1 
ATOM   112  C CD  . GLU A 1 17  ? -33.260 19.058  -17.947 1.00 14.90 ? 17  GLU A CD  1 
ATOM   113  O OE1 . GLU A 1 17  ? -34.166 18.220  -17.745 1.00 15.45 ? 17  GLU A OE1 1 
ATOM   114  O OE2 . GLU A 1 17  ? -32.631 19.121  -19.034 1.00 17.52 ? 17  GLU A OE2 1 
ATOM   115  N N   . LEU A 1 18  ? -37.186 19.461  -14.920 1.00 12.56 ? 18  LEU A N   1 
ATOM   116  C CA  . LEU A 1 18  ? -38.149 19.213  -13.856 1.00 11.75 ? 18  LEU A CA  1 
ATOM   117  C C   . LEU A 1 18  ? -38.127 17.739  -13.485 1.00 15.71 ? 18  LEU A C   1 
ATOM   118  O O   . LEU A 1 18  ? -38.251 16.867  -14.356 1.00 14.81 ? 18  LEU A O   1 
ATOM   119  C CB  . LEU A 1 18  ? -39.573 19.592  -14.274 1.00 12.84 ? 18  LEU A CB  1 
ATOM   120  C CG  . LEU A 1 18  ? -40.642 19.328  -13.206 1.00 15.33 ? 18  LEU A CG  1 
ATOM   121  C CD1 . LEU A 1 18  ? -41.630 20.485  -13.162 1.00 20.51 ? 18  LEU A CD1 1 
ATOM   122  C CD2 . LEU A 1 18  ? -41.355 17.998  -13.376 1.00 18.84 ? 18  LEU A CD2 1 
ATOM   123  N N   . ASP A 1 19  ? -38.070 17.473  -12.199 1.00 16.45 ? 19  ASP A N   1 
ATOM   124  C CA  . ASP A 1 19  ? -38.120 16.167  -11.586 1.00 17.97 ? 19  ASP A CA  1 
ATOM   125  C C   . ASP A 1 19  ? -39.412 16.126  -10.790 1.00 18.78 ? 19  ASP A C   1 
ATOM   126  O O   . ASP A 1 19  ? -39.527 16.846  -9.890  1.00 17.21 ? 19  ASP A O   1 
ATOM   127  C CB  . ASP A 1 19  ? -36.939 16.060  -10.639 1.00 20.44 ? 19  ASP A CB  1 
ATOM   128  C CG  . ASP A 1 19  ? -36.989 14.872  -9.697  1.00 26.32 ? 19  ASP A CG  1 
ATOM   129  O OD1 . ASP A 1 19  ? -37.566 13.869  -10.016 1.00 23.24 ? 19  ASP A OD1 1 
ATOM   130  O OD2 . ASP A 1 19  ? -36.361 14.980  -8.657  1.00 24.77 ? 19  ASP A OD2 1 
ATOM   131  N N   . GLY A 1 20  ? -40.340 15.270  -11.188 1.00 16.51 ? 20  GLY A N   1 
ATOM   132  C CA  . GLY A 1 20  ? -41.666 15.281  -10.611 1.00 18.35 ? 20  GLY A CA  1 
ATOM   133  C C   . GLY A 1 20  ? -42.093 13.938  -10.044 1.00 20.12 ? 20  GLY A C   1 
ATOM   134  O O   . GLY A 1 20  ? -41.642 12.873  -10.465 1.00 16.67 ? 20  GLY A O   1 
ATOM   135  N N   . ASP A 1 21  ? -42.994 14.021  -9.065  1.00 18.81 ? 21  ASP A N   1 
ATOM   136  C CA  . ASP A 1 21  ? -43.605 12.860  -8.422  1.00 21.26 ? 21  ASP A CA  1 
ATOM   137  C C   . ASP A 1 21  ? -44.996 13.300  -7.986  1.00 19.26 ? 21  ASP A C   1 
ATOM   138  O O   . ASP A 1 21  ? -45.110 14.159  -7.113  1.00 18.14 ? 21  ASP A O   1 
ATOM   139  C CB  . ASP A 1 21  ? -42.772 12.391  -7.228  1.00 20.31 ? 21  ASP A CB  1 
ATOM   140  C CG  . ASP A 1 21  ? -43.326 11.126  -6.581  1.00 27.71 ? 21  ASP A CG  1 
ATOM   141  O OD1 . ASP A 1 21  ? -44.488 10.765  -6.846  1.00 26.58 ? 21  ASP A OD1 1 
ATOM   142  O OD2 . ASP A 1 21  ? -42.601 10.490  -5.789  1.00 29.94 ? 21  ASP A OD2 1 
ATOM   143  N N   . VAL A 1 22  ? -46.038 12.721  -8.573  1.00 17.81 ? 22  VAL A N   1 
ATOM   144  C CA  . VAL A 1 22  ? -47.420 13.063  -8.232  1.00 22.06 ? 22  VAL A CA  1 
ATOM   145  C C   . VAL A 1 22  ? -48.143 11.773  -7.874  1.00 18.24 ? 22  VAL A C   1 
ATOM   146  O O   . VAL A 1 22  ? -48.328 10.905  -8.733  1.00 20.72 ? 22  VAL A O   1 
ATOM   147  C CB  . VAL A 1 22  ? -48.140 13.791  -9.384  1.00 18.62 ? 22  VAL A CB  1 
ATOM   148  C CG1 . VAL A 1 22  ? -49.604 14.014  -9.017  1.00 20.19 ? 22  VAL A CG1 1 
ATOM   149  C CG2 . VAL A 1 22  ? -47.447 15.138  -9.710  1.00 15.82 ? 22  VAL A CG2 1 
ATOM   150  N N   . ASN A 1 23  ? -48.545 11.644  -6.611  1.00 23.29 ? 23  ASN A N   1 
ATOM   151  C CA  . ASN A 1 23  ? -49.185 10.417  -6.121  1.00 22.63 ? 23  ASN A CA  1 
ATOM   152  C C   . ASN A 1 23  ? -48.335 9.186   -6.428  1.00 24.93 ? 23  ASN A C   1 
ATOM   153  O O   . ASN A 1 23  ? -48.851 8.118   -6.760  1.00 24.09 ? 23  ASN A O   1 
ATOM   154  C CB  . ASN A 1 23  ? -50.593 10.240  -6.701  1.00 25.31 ? 23  ASN A CB  1 
ATOM   155  C CG  . ASN A 1 23  ? -51.639 11.041  -5.955  1.00 24.67 ? 23  ASN A CG  1 
ATOM   156  O OD1 . ASN A 1 23  ? -51.345 12.086  -5.379  1.00 24.62 ? 23  ASN A OD1 1 
ATOM   157  N ND2 . ASN A 1 23  ? -52.866 10.526  -5.926  1.00 27.63 ? 23  ASN A ND2 1 
ATOM   158  N N   . GLY A 1 24  ? -47.016 9.337   -6.341  1.00 21.74 ? 24  GLY A N   1 
ATOM   159  C CA  . GLY A 1 24  ? -46.133 8.250   -6.677  1.00 25.39 ? 24  GLY A CA  1 
ATOM   160  C C   . GLY A 1 24  ? -45.876 8.068   -8.153  1.00 27.00 ? 24  GLY A C   1 
ATOM   161  O O   . GLY A 1 24  ? -45.002 7.272   -8.514  1.00 29.56 ? 24  GLY A O   1 
ATOM   162  N N   . HIS A 1 25  ? -46.607 8.763   -9.025  1.00 24.31 ? 25  HIS A N   1 
ATOM   163  C CA  . HIS A 1 25  ? -46.336 8.710   -10.456 1.00 24.11 ? 25  HIS A CA  1 
ATOM   164  C C   . HIS A 1 25  ? -45.147 9.622   -10.732 1.00 23.51 ? 25  HIS A C   1 
ATOM   165  O O   . HIS A 1 25  ? -45.257 10.846  -10.612 1.00 22.97 ? 25  HIS A O   1 
ATOM   166  C CB  . HIS A 1 25  ? -47.568 9.121   -11.258 1.00 26.76 ? 25  HIS A CB  1 
ATOM   167  C CG  . HIS A 1 25  ? -48.762 8.245   -11.015 1.00 29.86 ? 25  HIS A CG  1 
ATOM   168  N ND1 . HIS A 1 25  ? -48.882 6.979   -11.551 1.00 31.89 ? 25  HIS A ND1 1 
ATOM   169  C CD2 . HIS A 1 25  ? -49.881 8.447   -10.278 1.00 29.13 ? 25  HIS A CD2 1 
ATOM   170  C CE1 . HIS A 1 25  ? -50.027 6.445   -11.164 1.00 31.59 ? 25  HIS A CE1 1 
ATOM   171  N NE2 . HIS A 1 25  ? -50.655 7.317   -10.394 1.00 30.76 ? 25  HIS A NE2 1 
ATOM   172  N N   . LYS A 1 26  ? -43.998 9.030   -11.040 1.00 21.40 ? 26  LYS A N   1 
ATOM   173  C CA  . LYS A 1 26  ? -42.764 9.777   -11.208 1.00 20.19 ? 26  LYS A CA  1 
ATOM   174  C C   . LYS A 1 26  ? -42.536 10.075  -12.681 1.00 16.24 ? 26  LYS A C   1 
ATOM   175  O O   . LYS A 1 26  ? -42.933 9.306   -13.556 1.00 19.49 ? 26  LYS A O   1 
ATOM   176  C CB  . LYS A 1 26  ? -41.573 9.005   -10.631 1.00 19.92 ? 26  LYS A CB  1 
ATOM   177  C CG  . LYS A 1 26  ? -41.694 8.732   -9.133  1.00 25.05 ? 26  LYS A CG  1 
ATOM   178  C CD  . LYS A 1 26  ? -40.752 7.635   -8.659  1.00 24.13 ? 26  LYS A CD  1 
ATOM   179  C CE  . LYS A 1 26  ? -40.863 7.451   -7.152  1.00 33.48 ? 26  LYS A CE  1 
ATOM   180  N NZ  . LYS A 1 26  ? -40.774 8.760   -6.424  1.00 35.82 ? 26  LYS A NZ  1 
ATOM   181  N N   . PHE A 1 27  ? -41.902 11.211  -12.954 1.00 15.92 ? 27  PHE A N   1 
ATOM   182  C CA  . PHE A 1 27  ? -41.745 11.645  -14.333 1.00 15.65 ? 27  PHE A CA  1 
ATOM   183  C C   . PHE A 1 27  ? -40.678 12.720  -14.397 1.00 17.33 ? 27  PHE A C   1 
ATOM   184  O O   . PHE A 1 27  ? -40.287 13.294  -13.377 1.00 18.62 ? 27  PHE A O   1 
ATOM   185  C CB  . PHE A 1 27  ? -43.072 12.150  -14.920 1.00 17.37 ? 27  PHE A CB  1 
ATOM   186  C CG  . PHE A 1 27  ? -43.622 13.383  -14.237 1.00 19.35 ? 27  PHE A CG  1 
ATOM   187  C CD1 . PHE A 1 27  ? -44.356 13.261  -13.068 1.00 18.90 ? 27  PHE A CD1 1 
ATOM   188  C CD2 . PHE A 1 27  ? -43.442 14.653  -14.782 1.00 17.04 ? 27  PHE A CD2 1 
ATOM   189  C CE1 . PHE A 1 27  ? -44.880 14.388  -12.440 1.00 21.48 ? 27  PHE A CE1 1 
ATOM   190  C CE2 . PHE A 1 27  ? -43.971 15.785  -14.163 1.00 16.91 ? 27  PHE A CE2 1 
ATOM   191  C CZ  . PHE A 1 27  ? -44.686 15.650  -12.992 1.00 15.86 ? 27  PHE A CZ  1 
ATOM   192  N N   . SER A 1 28  ? -40.212 12.986  -15.614 1.00 16.06 ? 28  SER A N   1 
ATOM   193  C CA  . SER A 1 28  ? -39.249 14.046  -15.839 1.00 16.50 ? 28  SER A CA  1 
ATOM   194  C C   . SER A 1 28  ? -39.680 14.864  -17.050 1.00 16.16 ? 28  SER A C   1 
ATOM   195  O O   . SER A 1 28  ? -40.258 14.334  -18.003 1.00 15.04 ? 28  SER A O   1 
ATOM   196  C CB  . SER A 1 28  ? -37.846 13.474  -16.031 1.00 16.46 ? 28  SER A CB  1 
ATOM   197  O OG  . SER A 1 28  ? -36.909 14.509  -16.270 1.00 21.17 ? 28  SER A OG  1 
ATOM   198  N N   . VAL A 1 29  ? -39.407 16.167  -17.002 1.00 15.12 ? 29  VAL A N   1 
ATOM   199  C CA  . VAL A 1 29  ? -39.713 17.078  -18.104 1.00 14.81 ? 29  VAL A CA  1 
ATOM   200  C C   . VAL A 1 29  ? -38.455 17.878  -18.401 1.00 15.25 ? 29  VAL A C   1 
ATOM   201  O O   . VAL A 1 29  ? -37.820 18.404  -17.479 1.00 14.06 ? 29  VAL A O   1 
ATOM   202  C CB  . VAL A 1 29  ? -40.891 18.024  -17.771 1.00 12.29 ? 29  VAL A CB  1 
ATOM   203  C CG1 . VAL A 1 29  ? -41.045 19.108  -18.841 1.00 12.91 ? 29  VAL A CG1 1 
ATOM   204  C CG2 . VAL A 1 29  ? -42.192 17.239  -17.627 1.00 16.02 ? 29  VAL A CG2 1 
ATOM   205  N N   . SER A 1 30  ? -38.091 17.968  -19.680 1.00 11.57 ? 30  SER A N   1 
ATOM   206  C CA  . SER A 1 30  ? -36.996 18.812  -20.126 1.00 15.39 ? 30  SER A CA  1 
ATOM   207  C C   . SER A 1 30  ? -37.559 19.887  -21.044 1.00 17.02 ? 30  SER A C   1 
ATOM   208  O O   . SER A 1 30  ? -38.458 19.619  -21.847 1.00 17.16 ? 30  SER A O   1 
ATOM   209  C CB  . SER A 1 30  ? -35.937 17.998  -20.880 1.00 19.33 ? 30  SER A CB  1 
ATOM   210  O OG  . SER A 1 30  ? -35.141 17.248  -19.969 1.00 21.91 ? 30  SER A OG  1 
ATOM   211  N N   . GLY A 1 31  ? -37.027 21.097  -20.944 1.00 13.08 ? 31  GLY A N   1 
ATOM   212  C CA  . GLY A 1 31  ? -37.426 22.167  -21.835 1.00 12.09 ? 31  GLY A CA  1 
ATOM   213  C C   . GLY A 1 31  ? -36.213 22.903  -22.357 1.00 12.88 ? 31  GLY A C   1 
ATOM   214  O O   . GLY A 1 31  ? -35.192 23.016  -21.683 1.00 12.91 ? 31  GLY A O   1 
ATOM   215  N N   . GLU A 1 32  ? -36.326 23.396  -23.586 1.00 13.30 ? 32  GLU A N   1 
ATOM   216  C CA  . GLU A 1 32  ? -35.264 24.256  -24.090 1.00 15.76 ? 32  GLU A CA  1 
ATOM   217  C C   . GLU A 1 32  ? -35.854 25.270  -25.055 1.00 15.18 ? 32  GLU A C   1 
ATOM   218  O O   . GLU A 1 32  ? -36.902 25.045  -25.666 1.00 13.22 ? 32  GLU A O   1 
ATOM   219  C CB  . GLU A 1 32  ? -34.140 23.415  -24.714 1.00 21.92 ? 32  GLU A CB  1 
ATOM   220  C CG  . GLU A 1 32  ? -34.565 22.515  -25.837 1.00 29.46 ? 32  GLU A CG  1 
ATOM   221  C CD  . GLU A 1 32  ? -33.374 21.848  -26.512 1.00 43.41 ? 32  GLU A CD  1 
ATOM   222  O OE1 . GLU A 1 32  ? -32.721 21.006  -25.853 1.00 38.18 ? 32  GLU A OE1 1 
ATOM   223  O OE2 . GLU A 1 32  ? -33.094 22.170  -27.690 1.00 48.03 ? 32  GLU A OE2 1 
ATOM   224  N N   . GLY A 1 33  ? -35.201 26.414  -25.131 1.00 15.70 ? 33  GLY A N   1 
ATOM   225  C CA  . GLY A 1 33  ? -35.612 27.446  -26.054 1.00 16.36 ? 33  GLY A CA  1 
ATOM   226  C C   . GLY A 1 33  ? -34.844 28.709  -25.751 1.00 16.67 ? 33  GLY A C   1 
ATOM   227  O O   . GLY A 1 33  ? -33.657 28.652  -25.427 1.00 16.03 ? 33  GLY A O   1 
ATOM   228  N N   . GLU A 1 34  ? -35.497 29.856  -25.815 1.00 17.90 ? 34  GLU A N   1 
ATOM   229  C CA  . GLU A 1 34  ? -34.761 31.097  -25.633 1.00 15.54 ? 34  GLU A CA  1 
ATOM   230  C C   . GLU A 1 34  ? -35.703 32.178  -25.139 1.00 16.73 ? 34  GLU A C   1 
ATOM   231  O O   . GLU A 1 34  ? -36.923 32.111  -25.331 1.00 16.30 ? 34  GLU A O   1 
ATOM   232  C CB  . GLU A 1 34  ? -34.092 31.572  -26.931 1.00 19.81 ? 34  GLU A CB  1 
ATOM   233  C CG  . GLU A 1 34  ? -34.979 31.525  -28.136 1.00 25.88 ? 34  GLU A CG  1 
ATOM   234  C CD  . GLU A 1 34  ? -34.173 31.693  -29.407 1.00 37.98 ? 34  GLU A CD  1 
ATOM   235  O OE1 . GLU A 1 34  ? -34.654 32.404  -30.319 1.00 41.63 ? 34  GLU A OE1 1 
ATOM   236  O OE2 . GLU A 1 34  ? -33.039 31.158  -29.468 1.00 39.56 ? 34  GLU A OE2 1 
ATOM   237  N N   . GLY A 1 35  ? -35.102 33.207  -24.558 1.00 15.16 ? 35  GLY A N   1 
ATOM   238  C CA  . GLY A 1 35  ? -35.855 34.333  -24.045 1.00 14.94 ? 35  GLY A CA  1 
ATOM   239  C C   . GLY A 1 35  ? -35.221 35.654  -24.426 1.00 18.99 ? 35  GLY A C   1 
ATOM   240  O O   . GLY A 1 35  ? -33.997 35.780  -24.539 1.00 18.34 ? 35  GLY A O   1 
ATOM   241  N N   . ASP A 1 36  ? -36.084 36.649  -24.611 1.00 15.39 ? 36  ASP A N   1 
ATOM   242  C CA  . ASP A 1 36  ? -35.696 38.006  -24.996 1.00 15.96 ? 36  ASP A CA  1 
ATOM   243  C C   . ASP A 1 36  ? -36.369 38.918  -23.984 1.00 18.49 ? 36  ASP A C   1 
ATOM   244  O O   . ASP A 1 36  ? -37.535 39.286  -24.157 1.00 18.54 ? 36  ASP A O   1 
ATOM   245  C CB  . ASP A 1 36  ? -36.133 38.317  -26.417 1.00 15.91 ? 36  ASP A CB  1 
ATOM   246  C CG  . ASP A 1 36  ? -35.685 39.697  -26.878 1.00 23.46 ? 36  ASP A CG  1 
ATOM   247  O OD1 . ASP A 1 36  ? -35.200 40.479  -26.043 1.00 25.10 ? 36  ASP A OD1 1 
ATOM   248  O OD2 . ASP A 1 36  ? -35.867 40.010  -28.073 1.00 28.90 ? 36  ASP A OD2 1 
ATOM   249  N N   . ALA A 1 37  ? -35.639 39.269  -22.929 1.00 16.95 ? 37  ALA A N   1 
ATOM   250  C CA  . ALA A 1 37  ? -36.204 40.129  -21.907 1.00 18.37 ? 37  ALA A CA  1 
ATOM   251  C C   . ALA A 1 37  ? -36.452 41.544  -22.411 1.00 20.90 ? 37  ALA A C   1 
ATOM   252  O O   . ALA A 1 37  ? -37.226 42.277  -21.791 1.00 22.36 ? 37  ALA A O   1 
ATOM   253  C CB  . ALA A 1 37  ? -35.287 40.160  -20.687 1.00 20.37 ? 37  ALA A CB  1 
ATOM   254  N N   . THR A 1 38  ? -35.830 41.948  -23.520 1.00 20.74 ? 38  THR A N   1 
ATOM   255  C CA  . THR A 1 38  ? -36.039 43.312  -23.998 1.00 21.53 ? 38  THR A CA  1 
ATOM   256  C C   . THR A 1 38  ? -37.458 43.502  -24.521 1.00 23.13 ? 38  THR A C   1 
ATOM   257  O O   . THR A 1 38  ? -38.053 44.572  -24.350 1.00 24.12 ? 38  THR A O   1 
ATOM   258  C CB  . THR A 1 38  ? -35.009 43.667  -25.068 1.00 25.58 ? 38  THR A CB  1 
ATOM   259  O OG1 . THR A 1 38  ? -33.697 43.465  -24.533 1.00 28.26 ? 38  THR A OG1 1 
ATOM   260  C CG2 . THR A 1 38  ? -35.153 45.131  -25.478 1.00 31.75 ? 38  THR A CG2 1 
ATOM   261  N N   . TYR A 1 39  ? -38.022 42.474  -25.144 1.00 25.09 ? 39  TYR A N   1 
ATOM   262  C CA  . TYR A 1 39  ? -39.422 42.501  -25.529 1.00 24.42 ? 39  TYR A CA  1 
ATOM   263  C C   . TYR A 1 39  ? -40.304 41.722  -24.568 1.00 21.45 ? 39  TYR A C   1 
ATOM   264  O O   . TYR A 1 39  ? -41.526 41.899  -24.593 1.00 21.40 ? 39  TYR A O   1 
ATOM   265  C CB  . TYR A 1 39  ? -39.603 41.918  -26.938 1.00 21.37 ? 39  TYR A CB  1 
ATOM   266  C CG  . TYR A 1 39  ? -40.953 42.223  -27.548 1.00 23.40 ? 39  TYR A CG  1 
ATOM   267  C CD1 . TYR A 1 39  ? -41.473 43.514  -27.526 1.00 26.00 ? 39  TYR A CD1 1 
ATOM   268  C CD2 . TYR A 1 39  ? -41.731 41.219  -28.103 1.00 21.32 ? 39  TYR A CD2 1 
ATOM   269  C CE1 . TYR A 1 39  ? -42.714 43.801  -28.091 1.00 22.99 ? 39  TYR A CE1 1 
ATOM   270  C CE2 . TYR A 1 39  ? -42.983 41.497  -28.659 1.00 23.61 ? 39  TYR A CE2 1 
ATOM   271  C CZ  . TYR A 1 39  ? -43.465 42.792  -28.641 1.00 23.67 ? 39  TYR A CZ  1 
ATOM   272  O OH  . TYR A 1 39  ? -44.699 43.088  -29.183 1.00 24.99 ? 39  TYR A OH  1 
ATOM   273  N N   . GLY A 1 40  ? -39.722 40.863  -23.737 1.00 16.31 ? 40  GLY A N   1 
ATOM   274  C CA  . GLY A 1 40  ? -40.532 39.998  -22.901 1.00 17.16 ? 40  GLY A CA  1 
ATOM   275  C C   . GLY A 1 40  ? -41.067 38.786  -23.630 1.00 21.25 ? 40  GLY A C   1 
ATOM   276  O O   . GLY A 1 40  ? -42.227 38.407  -23.433 1.00 21.14 ? 40  GLY A O   1 
ATOM   277  N N   . LYS A 1 41  ? -40.249 38.147  -24.459 1.00 16.61 ? 41  LYS A N   1 
ATOM   278  C CA  . LYS A 1 41  ? -40.692 37.034  -25.292 1.00 16.96 ? 41  LYS A CA  1 
ATOM   279  C C   . LYS A 1 41  ? -39.957 35.762  -24.894 1.00 15.53 ? 41  LYS A C   1 
ATOM   280  O O   . LYS A 1 41  ? -38.730 35.782  -24.733 1.00 16.42 ? 41  LYS A O   1 
ATOM   281  C CB  . LYS A 1 41  ? -40.447 37.328  -26.770 1.00 19.87 ? 41  LYS A CB  1 
ATOM   282  C CG  . LYS A 1 41  ? -40.943 36.210  -27.684 1.00 21.04 ? 41  LYS A CG  1 
ATOM   283  C CD  . LYS A 1 41  ? -40.902 36.626  -29.144 1.00 24.22 ? 41  LYS A CD  1 
ATOM   284  C CE  . LYS A 1 41  ? -39.743 35.974  -29.882 1.00 37.65 ? 41  LYS A CE  1 
ATOM   285  N NZ  . LYS A 1 41  ? -40.162 34.784  -30.669 1.00 40.30 ? 41  LYS A NZ  1 
ATOM   286  N N   . LEU A 1 42  ? -40.712 34.664  -24.753 1.00 16.31 ? 42  LEU A N   1 
ATOM   287  C CA  . LEU A 1 42  ? -40.210 33.341  -24.392 1.00 18.21 ? 42  LEU A CA  1 
ATOM   288  C C   . LEU A 1 42  ? -40.702 32.333  -25.414 1.00 16.86 ? 42  LEU A C   1 
ATOM   289  O O   . LEU A 1 42  ? -41.901 32.293  -25.710 1.00 17.50 ? 42  LEU A O   1 
ATOM   290  C CB  . LEU A 1 42  ? -40.727 32.893  -23.020 1.00 18.75 ? 42  LEU A CB  1 
ATOM   291  C CG  . LEU A 1 42  ? -40.270 33.616  -21.773 1.00 24.41 ? 42  LEU A CG  1 
ATOM   292  C CD1 . LEU A 1 42  ? -40.920 32.973  -20.550 1.00 23.86 ? 42  LEU A CD1 1 
ATOM   293  C CD2 . LEU A 1 42  ? -38.777 33.492  -21.708 1.00 23.49 ? 42  LEU A CD2 1 
ATOM   294  N N   . THR A 1 43  ? -39.794 31.504  -25.926 1.00 15.25 ? 43  THR A N   1 
ATOM   295  C CA  . THR A 1 43  ? -40.146 30.380  -26.789 1.00 20.60 ? 43  THR A CA  1 
ATOM   296  C C   . THR A 1 43  ? -39.474 29.124  -26.251 1.00 17.51 ? 43  THR A C   1 
ATOM   297  O O   . THR A 1 43  ? -38.247 29.082  -26.116 1.00 16.96 ? 43  THR A O   1 
ATOM   298  C CB  . THR A 1 43  ? -39.741 30.646  -28.244 1.00 22.39 ? 43  THR A CB  1 
ATOM   299  O OG1 . THR A 1 43  ? -38.319 30.712  -28.334 1.00 28.47 ? 43  THR A OG1 1 
ATOM   300  C CG2 . THR A 1 43  ? -40.314 31.947  -28.740 1.00 22.32 ? 43  THR A CG2 1 
ATOM   301  N N   . LEU A 1 44  ? -40.275 28.110  -25.938 1.00 16.70 ? 44  LEU A N   1 
ATOM   302  C CA  . LEU A 1 44  ? -39.789 26.906  -25.287 1.00 15.97 ? 44  LEU A CA  1 
ATOM   303  C C   . LEU A 1 44  ? -40.533 25.699  -25.831 1.00 16.54 ? 44  LEU A C   1 
ATOM   304  O O   . LEU A 1 44  ? -41.720 25.789  -26.151 1.00 20.30 ? 44  LEU A O   1 
ATOM   305  C CB  . LEU A 1 44  ? -39.997 26.994  -23.776 1.00 17.57 ? 44  LEU A CB  1 
ATOM   306  C CG  . LEU A 1 44  ? -39.177 28.116  -23.124 1.00 17.16 ? 44  LEU A CG  1 
ATOM   307  C CD1 . LEU A 1 44  ? -39.815 28.499  -21.853 1.00 19.97 ? 44  LEU A CD1 1 
ATOM   308  C CD2 . LEU A 1 44  ? -37.771 27.606  -22.878 1.00 19.85 ? 44  LEU A CD2 1 
ATOM   309  N N   . LYS A 1 45  ? -39.836 24.572  -25.923 1.00 14.15 ? 45  LYS A N   1 
ATOM   310  C CA  . LYS A 1 45  ? -40.456 23.288  -26.194 1.00 14.28 ? 45  LYS A CA  1 
ATOM   311  C C   . LYS A 1 45  ? -40.115 22.357  -25.043 1.00 13.77 ? 45  LYS A C   1 
ATOM   312  O O   . LYS A 1 45  ? -38.956 22.280  -24.632 1.00 14.13 ? 45  LYS A O   1 
ATOM   313  C CB  . LYS A 1 45  ? -39.980 22.695  -27.519 1.00 15.16 ? 45  LYS A CB  1 
ATOM   314  C CG  . LYS A 1 45  ? -40.473 21.290  -27.753 1.00 14.79 ? 45  LYS A CG  1 
ATOM   315  C CD  . LYS A 1 45  ? -40.019 20.818  -29.137 1.00 18.25 ? 45  LYS A CD  1 
ATOM   316  C CE  . LYS A 1 45  ? -40.336 19.348  -29.366 1.00 22.74 ? 45  LYS A CE  1 
ATOM   317  N NZ  . LYS A 1 45  ? -39.842 18.921  -30.718 1.00 23.24 ? 45  LYS A NZ  1 
ATOM   318  N N   . PHE A 1 46  ? -41.133 21.688  -24.506 1.00 12.75 ? 46  PHE A N   1 
ATOM   319  C CA  . PHE A 1 46  ? -41.003 20.811  -23.354 1.00 14.00 ? 46  PHE A CA  1 
ATOM   320  C C   . PHE A 1 46  ? -41.347 19.398  -23.778 1.00 14.81 ? 46  PHE A C   1 
ATOM   321  O O   . PHE A 1 46  ? -42.312 19.193  -24.515 1.00 16.46 ? 46  PHE A O   1 
ATOM   322  C CB  . PHE A 1 46  ? -41.941 21.231  -22.226 1.00 12.45 ? 46  PHE A CB  1 
ATOM   323  C CG  . PHE A 1 46  ? -41.639 22.582  -21.667 1.00 13.49 ? 46  PHE A CG  1 
ATOM   324  C CD1 . PHE A 1 46  ? -40.704 22.734  -20.647 1.00 11.82 ? 46  PHE A CD1 1 
ATOM   325  C CD2 . PHE A 1 46  ? -42.297 23.701  -22.147 1.00 16.06 ? 46  PHE A CD2 1 
ATOM   326  C CE1 . PHE A 1 46  ? -40.426 23.985  -20.124 1.00 11.78 ? 46  PHE A CE1 1 
ATOM   327  C CE2 . PHE A 1 46  ? -42.025 24.951  -21.642 1.00 13.51 ? 46  PHE A CE2 1 
ATOM   328  C CZ  . PHE A 1 46  ? -41.084 25.097  -20.623 1.00 11.21 ? 46  PHE A CZ  1 
ATOM   329  N N   . ILE A 1 47  ? -40.573 18.430  -23.296 1.00 13.86 ? 47  ILE A N   1 
ATOM   330  C CA  . ILE A 1 47  ? -40.797 17.019  -23.573 1.00 15.00 ? 47  ILE A CA  1 
ATOM   331  C C   . ILE A 1 47  ? -40.883 16.274  -22.245 1.00 14.55 ? 47  ILE A C   1 
ATOM   332  O O   . ILE A 1 47  ? -40.066 16.507  -21.349 1.00 17.45 ? 47  ILE A O   1 
ATOM   333  C CB  . ILE A 1 47  ? -39.658 16.443  -24.442 1.00 19.05 ? 47  ILE A CB  1 
ATOM   334  C CG1 . ILE A 1 47  ? -39.642 17.135  -25.806 1.00 20.67 ? 47  ILE A CG1 1 
ATOM   335  C CG2 . ILE A 1 47  ? -39.782 14.925  -24.551 1.00 17.53 ? 47  ILE A CG2 1 
ATOM   336  C CD1 . ILE A 1 47  ? -38.736 16.487  -26.829 1.00 26.55 ? 47  ILE A CD1 1 
ATOM   337  N N   . CYS A 1 48  ? -41.879 15.403  -22.103 1.00 15.19 ? 48  CYS A N   1 
ATOM   338  C CA  . CYS A 1 48  ? -41.857 14.420  -21.024 1.00 13.92 ? 48  CYS A CA  1 
ATOM   339  C C   . CYS A 1 48  ? -40.902 13.311  -21.438 1.00 19.53 ? 48  CYS A C   1 
ATOM   340  O O   . CYS A 1 48  ? -41.197 12.539  -22.357 1.00 18.99 ? 48  CYS A O   1 
ATOM   341  C CB  . CYS A 1 48  ? -43.242 13.855  -20.728 1.00 16.41 ? 48  CYS A CB  1 
ATOM   342  S SG  . CYS A 1 48  ? -43.184 12.677  -19.340 1.00 17.40 ? 48  CYS A SG  1 
ATOM   343  N N   . THR A 1 49  ? -39.747 13.250  -20.789 1.00 16.54 ? 49  THR A N   1 
ATOM   344  C CA  . THR A 1 49  ? -38.697 12.337  -21.221 1.00 17.02 ? 49  THR A CA  1 
ATOM   345  C C   . THR A 1 49  ? -38.831 10.949  -20.614 1.00 20.55 ? 49  THR A C   1 
ATOM   346  O O   . THR A 1 49  ? -37.960 10.101  -20.854 1.00 20.00 ? 49  THR A O   1 
ATOM   347  C CB  . THR A 1 49  ? -37.330 12.915  -20.868 1.00 17.50 ? 49  THR A CB  1 
ATOM   348  O OG1 . THR A 1 49  ? -37.332 13.283  -19.484 1.00 17.60 ? 49  THR A OG1 1 
ATOM   349  C CG2 . THR A 1 49  ? -37.021 14.143  -21.743 1.00 17.25 ? 49  THR A CG2 1 
ATOM   350  N N   . THR A 1 50  ? -39.892 10.686  -19.847 1.00 17.09 ? 50  THR A N   1 
ATOM   351  C CA  . THR A 1 50  ? -40.066 9.390   -19.210 1.00 17.53 ? 50  THR A CA  1 
ATOM   352  C C   . THR A 1 50  ? -41.262 8.629   -19.774 1.00 19.46 ? 50  THR A C   1 
ATOM   353  O O   . THR A 1 50  ? -41.557 7.527   -19.308 1.00 22.87 ? 50  THR A O   1 
ATOM   354  C CB  . THR A 1 50  ? -40.194 9.544   -17.689 1.00 16.64 ? 50  THR A CB  1 
ATOM   355  O OG1 . THR A 1 50  ? -41.163 10.559  -17.375 1.00 19.82 ? 50  THR A OG1 1 
ATOM   356  C CG2 . THR A 1 50  ? -38.848 9.948   -17.090 1.00 15.53 ? 50  THR A CG2 1 
ATOM   357  N N   . GLY A 1 51  ? -41.936 9.172   -20.786 1.00 20.02 ? 51  GLY A N   1 
ATOM   358  C CA  . GLY A 1 51  ? -43.122 8.527   -21.315 1.00 21.37 ? 51  GLY A CA  1 
ATOM   359  C C   . GLY A 1 51  ? -44.281 9.496   -21.356 1.00 19.71 ? 51  GLY A C   1 
ATOM   360  O O   . GLY A 1 51  ? -44.093 10.667  -21.699 1.00 19.37 ? 51  GLY A O   1 
ATOM   361  N N   . LYS A 1 52  ? -45.475 9.042   -21.009 1.00 17.29 ? 52  LYS A N   1 
ATOM   362  C CA  . LYS A 1 52  ? -46.656 9.899   -21.023 1.00 23.18 ? 52  LYS A CA  1 
ATOM   363  C C   . LYS A 1 52  ? -46.688 10.749  -19.754 1.00 17.89 ? 52  LYS A C   1 
ATOM   364  O O   . LYS A 1 52  ? -46.471 10.241  -18.655 1.00 21.10 ? 52  LYS A O   1 
ATOM   365  C CB  . LYS A 1 52  ? -47.914 9.034   -21.135 1.00 25.63 ? 52  LYS A CB  1 
ATOM   366  C CG  . LYS A 1 52  ? -49.136 9.734   -21.735 1.00 34.33 ? 52  LYS A CG  1 
ATOM   367  C CD  . LYS A 1 52  ? -50.247 9.887   -20.701 1.00 33.18 ? 52  LYS A CD  1 
ATOM   368  C CE  . LYS A 1 52  ? -51.555 10.353  -21.332 1.00 33.00 ? 52  LYS A CE  1 
ATOM   369  N NZ  . LYS A 1 52  ? -52.212 9.275   -22.119 1.00 45.08 ? 52  LYS A NZ  1 
ATOM   370  N N   . LEU A 1 53  ? -46.943 12.045  -19.899 1.00 19.71 ? 53  LEU A N   1 
ATOM   371  C CA  . LEU A 1 53  ? -47.032 12.909  -18.717 1.00 16.95 ? 53  LEU A CA  1 
ATOM   372  C C   . LEU A 1 53  ? -48.227 12.487  -17.861 1.00 17.92 ? 53  LEU A C   1 
ATOM   373  O O   . LEU A 1 53  ? -49.344 12.407  -18.374 1.00 21.22 ? 53  LEU A O   1 
ATOM   374  C CB  . LEU A 1 53  ? -47.163 14.382  -19.131 1.00 16.04 ? 53  LEU A CB  1 
ATOM   375  C CG  . LEU A 1 53  ? -46.908 15.441  -18.047 1.00 16.64 ? 53  LEU A CG  1 
ATOM   376  C CD1 . LEU A 1 53  ? -45.463 15.377  -17.543 1.00 18.03 ? 53  LEU A CD1 1 
ATOM   377  C CD2 . LEU A 1 53  ? -47.242 16.850  -18.571 1.00 16.33 ? 53  LEU A CD2 1 
ATOM   378  N N   . PRO A 1 54  ? -48.041 12.216  -16.567 1.00 16.39 ? 54  PRO A N   1 
ATOM   379  C CA  . PRO A 1 54  ? -49.162 11.756  -15.733 1.00 20.49 ? 54  PRO A CA  1 
ATOM   380  C C   . PRO A 1 54  ? -50.097 12.852  -15.241 1.00 21.89 ? 54  PRO A C   1 
ATOM   381  O O   . PRO A 1 54  ? -51.081 12.529  -14.560 1.00 19.61 ? 54  PRO A O   1 
ATOM   382  C CB  . PRO A 1 54  ? -48.461 11.068  -14.547 1.00 20.24 ? 54  PRO A CB  1 
ATOM   383  C CG  . PRO A 1 54  ? -47.130 11.736  -14.447 1.00 23.89 ? 54  PRO A CG  1 
ATOM   384  C CD  . PRO A 1 54  ? -46.766 12.248  -15.830 1.00 19.70 ? 54  PRO A CD  1 
ATOM   385  N N   . VAL A 1 55  ? -49.817 14.122  -15.540 1.00 17.91 ? 55  VAL A N   1 
ATOM   386  C CA  . VAL A 1 55  ? -50.711 15.249  -15.255 1.00 18.56 ? 55  VAL A CA  1 
ATOM   387  C C   . VAL A 1 55  ? -50.909 16.031  -16.552 1.00 18.28 ? 55  VAL A C   1 
ATOM   388  O O   . VAL A 1 55  ? -50.172 15.798  -17.523 1.00 16.81 ? 55  VAL A O   1 
ATOM   389  C CB  . VAL A 1 55  ? -50.156 16.157  -14.145 1.00 16.73 ? 55  VAL A CB  1 
ATOM   390  C CG1 . VAL A 1 55  ? -49.958 15.396  -12.837 1.00 16.14 ? 55  VAL A CG1 1 
ATOM   391  C CG2 . VAL A 1 55  ? -48.835 16.819  -14.616 1.00 14.89 ? 55  VAL A CG2 1 
ATOM   392  N N   . PRO A 1 56  ? -51.885 16.940  -16.646 1.00 17.75 ? 56  PRO A N   1 
ATOM   393  C CA  . PRO A 1 56  ? -52.026 17.704  -17.893 1.00 15.54 ? 56  PRO A CA  1 
ATOM   394  C C   . PRO A 1 56  ? -50.960 18.780  -18.004 1.00 15.68 ? 56  PRO A C   1 
ATOM   395  O O   . PRO A 1 56  ? -50.605 19.435  -17.019 1.00 16.35 ? 56  PRO A O   1 
ATOM   396  C CB  . PRO A 1 56  ? -53.434 18.320  -17.803 1.00 16.47 ? 56  PRO A CB  1 
ATOM   397  C CG  . PRO A 1 56  ? -54.108 17.647  -16.650 1.00 19.55 ? 56  PRO A CG  1 
ATOM   398  C CD  . PRO A 1 56  ? -53.015 17.163  -15.730 1.00 16.99 ? 56  PRO A CD  1 
ATOM   399  N N   . TRP A 1 57  ? -50.457 18.960  -19.230 1.00 14.44 ? 57  TRP A N   1 
ATOM   400  C CA  . TRP A 1 57  ? -49.442 19.977  -19.515 1.00 14.35 ? 57  TRP A CA  1 
ATOM   401  C C   . TRP A 1 57  ? -49.802 21.364  -18.999 1.00 13.74 ? 57  TRP A C   1 
ATOM   402  O O   . TRP A 1 57  ? -48.923 22.030  -18.426 1.00 13.59 ? 57  TRP A O   1 
ATOM   403  C CB  . TRP A 1 57  ? -49.183 20.038  -21.028 1.00 15.06 ? 57  TRP A CB  1 
ATOM   404  C CG  . TRP A 1 57  ? -48.248 18.971  -21.517 1.00 15.10 ? 57  TRP A CG  1 
ATOM   405  C CD1 . TRP A 1 57  ? -48.566 17.887  -22.284 1.00 15.97 ? 57  TRP A CD1 1 
ATOM   406  C CD2 . TRP A 1 57  ? -46.845 18.893  -21.268 1.00 13.37 ? 57  TRP A CD2 1 
ATOM   407  N NE1 . TRP A 1 57  ? -47.437 17.139  -22.539 1.00 16.47 ? 57  TRP A NE1 1 
ATOM   408  C CE2 . TRP A 1 57  ? -46.369 17.735  -21.912 1.00 16.07 ? 57  TRP A CE2 1 
ATOM   409  C CE3 . TRP A 1 57  ? -45.943 19.690  -20.559 1.00 14.10 ? 57  TRP A CE3 1 
ATOM   410  C CZ2 . TRP A 1 57  ? -45.028 17.361  -21.873 1.00 16.42 ? 57  TRP A CZ2 1 
ATOM   411  C CZ3 . TRP A 1 57  ? -44.611 19.318  -20.520 1.00 14.06 ? 57  TRP A CZ3 1 
ATOM   412  C CH2 . TRP A 1 57  ? -44.165 18.165  -21.174 1.00 14.29 ? 57  TRP A CH2 1 
ATOM   413  N N   . PRO A 1 58  ? -51.026 21.872  -19.178 1.00 13.86 ? 58  PRO A N   1 
ATOM   414  C CA  . PRO A 1 58  ? -51.314 23.215  -18.651 1.00 13.10 ? 58  PRO A CA  1 
ATOM   415  C C   . PRO A 1 58  ? -51.052 23.348  -17.163 1.00 12.96 ? 58  PRO A C   1 
ATOM   416  O O   . PRO A 1 58  ? -50.685 24.441  -16.720 1.00 13.90 ? 58  PRO A O   1 
ATOM   417  C CB  . PRO A 1 58  ? -52.798 23.424  -18.991 1.00 14.96 ? 58  PRO A CB  1 
ATOM   418  C CG  . PRO A 1 58  ? -53.065 22.507  -20.135 1.00 16.52 ? 58  PRO A CG  1 
ATOM   419  C CD  . PRO A 1 58  ? -52.198 21.302  -19.873 1.00 15.14 ? 58  PRO A CD  1 
ATOM   420  N N   . THR A 1 59  ? -51.182 22.271  -16.372 1.00 11.72 ? 59  THR A N   1 
ATOM   421  C CA  . THR A 1 59  ? -50.983 22.445  -14.939 1.00 12.75 ? 59  THR A CA  1 
ATOM   422  C C   . THR A 1 59  ? -49.531 22.695  -14.573 1.00 13.33 ? 59  THR A C   1 
ATOM   423  O O   . THR A 1 59  ? -49.270 23.102  -13.434 1.00 13.69 ? 59  THR A O   1 
ATOM   424  C CB  . THR A 1 59  ? -51.506 21.237  -14.146 1.00 13.44 ? 59  THR A CB  1 
ATOM   425  O OG1 . THR A 1 59  ? -50.715 20.065  -14.415 1.00 14.47 ? 59  THR A OG1 1 
ATOM   426  C CG2 . THR A 1 59  ? -52.934 20.952  -14.510 1.00 13.48 ? 59  THR A CG2 1 
ATOM   427  N N   . LEU A 1 60  ? -48.586 22.487  -15.498 1.00 13.82 ? 60  LEU A N   1 
ATOM   428  C CA  . LEU A 1 60  ? -47.171 22.705  -15.214 1.00 12.52 ? 60  LEU A CA  1 
ATOM   429  C C   . LEU A 1 60  ? -46.632 24.030  -15.735 1.00 12.11 ? 60  LEU A C   1 
ATOM   430  O O   . LEU A 1 60  ? -45.477 24.362  -15.443 1.00 12.70 ? 60  LEU A O   1 
ATOM   431  C CB  . LEU A 1 60  ? -46.310 21.582  -15.801 1.00 12.85 ? 60  LEU A CB  1 
ATOM   432  C CG  . LEU A 1 60  ? -46.602 20.171  -15.321 1.00 11.75 ? 60  LEU A CG  1 
ATOM   433  C CD1 . LEU A 1 60  ? -45.714 19.213  -16.092 1.00 11.44 ? 60  LEU A CD1 1 
ATOM   434  C CD2 . LEU A 1 60  ? -46.393 20.068  -13.818 1.00 14.75 ? 60  LEU A CD2 1 
ATOM   435  N N   . VAL A 1 61  ? -47.438 24.796  -16.479 1.00 12.04 ? 61  VAL A N   1 
ATOM   436  C CA  . VAL A 1 61  ? -46.945 26.009  -17.129 1.00 11.09 ? 61  VAL A CA  1 
ATOM   437  C C   . VAL A 1 61  ? -46.310 26.956  -16.117 1.00 13.29 ? 61  VAL A C   1 
ATOM   438  O O   . VAL A 1 61  ? -45.199 27.454  -16.329 1.00 11.73 ? 61  VAL A O   1 
ATOM   439  C CB  . VAL A 1 61  ? -48.077 26.692  -17.915 1.00 12.65 ? 61  VAL A CB  1 
ATOM   440  C CG1 . VAL A 1 61  ? -47.698 28.124  -18.265 1.00 14.31 ? 61  VAL A CG1 1 
ATOM   441  C CG2 . VAL A 1 61  ? -48.380 25.895  -19.185 1.00 14.11 ? 61  VAL A CG2 1 
ATOM   442  N N   . THR A 1 62  ? -47.003 27.240  -15.006 1.00 10.43 ? 62  THR A N   1 
ATOM   443  C CA  . THR A 1 62  ? -46.439 28.220  -14.077 1.00 10.59 ? 62  THR A CA  1 
ATOM   444  C C   . THR A 1 62  ? -45.142 27.720  -13.468 1.00 12.49 ? 62  THR A C   1 
ATOM   445  O O   . THR A 1 62  ? -44.248 28.522  -13.177 1.00 12.77 ? 62  THR A O   1 
ATOM   446  C CB  . THR A 1 62  ? -47.409 28.558  -12.951 1.00 9.58  ? 62  THR A CB  1 
ATOM   447  O OG1 . THR A 1 62  ? -47.943 27.346  -12.399 1.00 11.85 ? 62  THR A OG1 1 
ATOM   448  C CG2 . THR A 1 62  ? -48.524 29.452  -13.475 1.00 11.98 ? 62  THR A CG2 1 
ATOM   449  N N   . THR A 1 63  ? -45.021 26.404  -13.285 1.00 11.49 ? 63  THR A N   1 
ATOM   450  C CA  . THR A 1 63  ? -43.801 25.850  -12.698 1.00 12.46 ? 63  THR A CA  1 
ATOM   451  C C   . THR A 1 63  ? -42.635 25.937  -13.671 1.00 14.14 ? 63  THR A C   1 
ATOM   452  O O   . THR A 1 63  ? -41.525 26.335  -13.287 1.00 13.03 ? 63  THR A O   1 
ATOM   453  C CB  . THR A 1 63  ? -44.040 24.407  -12.256 1.00 13.26 ? 63  THR A CB  1 
ATOM   454  O OG1 . THR A 1 63  ? -45.112 24.363  -11.300 1.00 13.40 ? 63  THR A OG1 1 
ATOM   455  C CG2 . THR A 1 63  ? -42.780 23.821  -11.622 1.00 12.44 ? 63  THR A CG2 1 
ATOM   456  N N   . LEU A 1 64  ? -42.869 25.586  -14.941 1.00 11.87 ? 64  LEU A N   1 
ATOM   457  C CA  . LEU A 1 64  ? -41.806 25.533  -15.939 1.00 12.15 ? 64  LEU A CA  1 
ATOM   458  C C   . LEU A 1 64  ? -41.343 26.939  -16.346 1.00 13.11 ? 64  LEU A C   1 
ATOM   459  O O   . LEU A 1 64  ? -40.154 27.192  -16.577 1.00 13.37 ? 64  LEU A O   1 
ATOM   460  C CB  . LEU A 1 64  ? -42.288 24.755  -17.164 1.00 10.52 ? 64  LEU A CB  1 
ATOM   461  C CG  . LEU A 1 64  ? -42.708 23.310  -16.918 1.00 10.76 ? 64  LEU A CG  1 
ATOM   462  C CD1 . LEU A 1 64  ? -43.456 22.745  -18.155 1.00 9.82  ? 64  LEU A CD1 1 
ATOM   463  C CD2 . LEU A 1 64  ? -41.495 22.455  -16.583 1.00 11.41 ? 64  LEU A CD2 1 
HETATM 464  N N1  . CRO A 1 65  ? -42.518 27.715  -16.456 1.00 17.99 ? 66  CRO A N1  1 
HETATM 465  C CA1 . CRO A 1 65  ? -42.320 29.063  -16.731 1.00 20.90 ? 66  CRO A CA1 1 
HETATM 466  C CB1 . CRO A 1 65  ? -42.725 29.491  -18.135 1.00 23.20 ? 66  CRO A CB1 1 
HETATM 467  C CG1 . CRO A 1 65  ? -41.844 28.856  -19.177 1.00 24.40 ? 66  CRO A CG1 1 
HETATM 468  O OG1 . CRO A 1 65  ? -43.829 29.404  -18.378 1.00 24.62 ? 66  CRO A OG1 1 
HETATM 469  C C1  . CRO A 1 65  ? -42.742 30.061  -15.662 1.00 21.76 ? 66  CRO A C1  1 
HETATM 470  N N2  . CRO A 1 65  ? -43.849 30.705  -15.712 1.00 22.47 ? 66  CRO A N2  1 
HETATM 471  N N3  . CRO A 1 65  ? -42.196 30.265  -14.510 1.00 23.25 ? 66  CRO A N3  1 
HETATM 472  C C2  . CRO A 1 65  ? -42.985 31.015  -13.826 1.00 21.79 ? 66  CRO A C2  1 
HETATM 473  O O2  . CRO A 1 65  ? -42.772 31.427  -12.548 1.00 18.00 ? 66  CRO A O2  1 
HETATM 474  C CA2 . CRO A 1 65  ? -44.056 31.308  -14.603 1.00 21.45 ? 66  CRO A CA2 1 
HETATM 475  C CA3 . CRO A 1 65  ? -40.976 29.744  -13.997 1.00 20.45 ? 66  CRO A CA3 1 
HETATM 476  C C3  . CRO A 1 65  ? -39.769 30.677  -14.163 1.00 23.06 ? 66  CRO A C3  1 
HETATM 477  O O3  . CRO A 1 65  ? -38.847 30.414  -13.510 1.00 21.42 ? 66  CRO A O3  1 
HETATM 478  C CB2 . CRO A 1 65  ? -45.174 32.238  -14.163 1.00 22.13 ? 66  CRO A CB2 1 
HETATM 479  C CG2 . CRO A 1 65  ? -46.456 32.424  -14.946 1.00 23.78 ? 66  CRO A CG2 1 
HETATM 480  C CD1 . CRO A 1 65  ? -46.732 31.954  -16.209 1.00 24.17 ? 66  CRO A CD1 1 
HETATM 481  C CD2 . CRO A 1 65  ? -47.426 33.135  -14.304 1.00 25.01 ? 66  CRO A CD2 1 
HETATM 482  C CE1 . CRO A 1 65  ? -47.943 32.211  -16.784 1.00 18.44 ? 66  CRO A CE1 1 
HETATM 483  C CE2 . CRO A 1 65  ? -48.639 33.380  -14.852 1.00 21.78 ? 66  CRO A CE2 1 
HETATM 484  C CZ  . CRO A 1 65  ? -48.898 32.926  -16.104 1.00 24.82 ? 66  CRO A CZ  1 
HETATM 485  O OH  . CRO A 1 65  ? -50.122 33.193  -16.635 1.00 24.68 ? 66  CRO A OH  1 
ATOM   486  N N   . VAL A 1 66  ? -39.766 31.470  -15.195 1.00 13.01 ? 68  VAL A N   1 
ATOM   487  C CA  . VAL A 1 66  ? -38.560 32.255  -15.406 1.00 14.72 ? 68  VAL A CA  1 
ATOM   488  C C   . VAL A 1 66  ? -38.932 33.729  -15.551 1.00 13.99 ? 68  VAL A C   1 
ATOM   489  O O   . VAL A 1 66  ? -38.721 34.343  -16.589 1.00 13.37 ? 68  VAL A O   1 
ATOM   490  C CB  . VAL A 1 66  ? -37.761 31.724  -16.617 1.00 13.86 ? 68  VAL A CB  1 
ATOM   491  C CG1 . VAL A 1 66  ? -37.127 30.371  -16.277 1.00 14.33 ? 68  VAL A CG1 1 
ATOM   492  C CG2 . VAL A 1 66  ? -38.660 31.559  -17.839 1.00 14.09 ? 68  VAL A CG2 1 
ATOM   493  N N   . GLN A 1 67  ? -39.476 34.300  -14.471 1.00 15.35 ? 69  GLN A N   1 
ATOM   494  C CA  . GLN A 1 67  ? -39.965 35.673  -14.480 1.00 15.44 ? 69  GLN A CA  1 
ATOM   495  C C   . GLN A 1 67  ? -38.848 36.686  -14.658 1.00 17.45 ? 69  GLN A C   1 
ATOM   496  O O   . GLN A 1 67  ? -39.132 37.878  -14.825 1.00 15.86 ? 69  GLN A O   1 
ATOM   497  C CB  . GLN A 1 67  ? -40.781 35.914  -13.199 1.00 15.21 ? 69  GLN A CB  1 
ATOM   498  C CG  . GLN A 1 67  ? -41.995 34.957  -13.125 1.00 17.01 ? 69  GLN A CG  1 
ATOM   499  C CD  . GLN A 1 67  ? -42.687 34.934  -11.766 1.00 17.36 ? 69  GLN A CD  1 
ATOM   500  O OE1 . GLN A 1 67  ? -42.042 34.678  -10.748 1.00 18.63 ? 69  GLN A OE1 1 
ATOM   501  N NE2 . GLN A 1 67  ? -44.001 35.145  -11.752 1.00 15.37 ? 69  GLN A NE2 1 
ATOM   502  N N   . CYS A 1 68  ? -37.591 36.234  -14.681 1.00 16.58 ? 70  CYS A N   1 
ATOM   503  C CA  . CYS A 1 68  ? -36.486 37.113  -15.044 1.00 17.82 ? 70  CYS A CA  1 
ATOM   504  C C   . CYS A 1 68  ? -36.552 37.568  -16.500 1.00 14.97 ? 70  CYS A C   1 
ATOM   505  O O   . CYS A 1 68  ? -35.870 38.527  -16.873 1.00 17.50 ? 70  CYS A O   1 
ATOM   506  C CB  . CYS A 1 68  ? -35.146 36.412  -14.761 1.00 14.48 ? 70  CYS A CB  1 
ATOM   507  S SG  . CYS A 1 68  ? -34.990 34.708  -15.416 1.00 16.53 ? 70  CYS A SG  1 
ATOM   508  N N   . PHE A 1 69  ? -37.341 36.911  -17.338 1.00 13.61 ? 71  PHE A N   1 
ATOM   509  C CA  . PHE A 1 69  ? -37.457 37.335  -18.725 1.00 15.14 ? 71  PHE A CA  1 
ATOM   510  C C   . PHE A 1 69  ? -38.594 38.313  -18.954 1.00 16.56 ? 71  PHE A C   1 
ATOM   511  O O   . PHE A 1 69  ? -38.827 38.722  -20.095 1.00 17.65 ? 71  PHE A O   1 
ATOM   512  C CB  . PHE A 1 69  ? -37.623 36.123  -19.638 1.00 15.88 ? 71  PHE A CB  1 
ATOM   513  C CG  . PHE A 1 69  ? -36.353 35.385  -19.837 1.00 16.45 ? 71  PHE A CG  1 
ATOM   514  C CD1 . PHE A 1 69  ? -35.370 35.900  -20.673 1.00 16.75 ? 71  PHE A CD1 1 
ATOM   515  C CD2 . PHE A 1 69  ? -36.106 34.217  -19.158 1.00 14.91 ? 71  PHE A CD2 1 
ATOM   516  C CE1 . PHE A 1 69  ? -34.157 35.232  -20.844 1.00 16.71 ? 71  PHE A CE1 1 
ATOM   517  C CE2 . PHE A 1 69  ? -34.904 33.544  -19.323 1.00 15.83 ? 71  PHE A CE2 1 
ATOM   518  C CZ  . PHE A 1 69  ? -33.931 34.053  -20.169 1.00 15.33 ? 71  PHE A CZ  1 
ATOM   519  N N   . SER A 1 70  ? -39.288 38.712  -17.902 1.00 15.20 ? 72  SER A N   1 
ATOM   520  C CA  . SER A 1 70  ? -40.348 39.687  -18.076 1.00 19.13 ? 72  SER A CA  1 
ATOM   521  C C   . SER A 1 70  ? -39.757 41.012  -18.534 1.00 20.29 ? 72  SER A C   1 
ATOM   522  O O   . SER A 1 70  ? -38.650 41.391  -18.139 1.00 19.79 ? 72  SER A O   1 
ATOM   523  C CB  . SER A 1 70  ? -41.114 39.862  -16.775 1.00 20.47 ? 72  SER A CB  1 
ATOM   524  O OG  . SER A 1 70  ? -40.420 40.770  -15.963 1.00 32.60 ? 72  SER A OG  1 
ATOM   525  N N   . ARG A 1 71  ? -40.485 41.697  -19.408 1.00 17.62 ? 73  ARG A N   1 
ATOM   526  C CA  . ARG A 1 71  ? -40.071 43.005  -19.884 1.00 21.78 ? 73  ARG A CA  1 
ATOM   527  C C   . ARG A 1 71  ? -40.359 44.008  -18.768 1.00 25.08 ? 73  ARG A C   1 
ATOM   528  O O   . ARG A 1 71  ? -41.523 44.291  -18.461 1.00 25.94 ? 73  ARG A O   1 
ATOM   529  C CB  . ARG A 1 71  ? -40.827 43.349  -21.165 1.00 22.74 ? 73  ARG A CB  1 
ATOM   530  C CG  . ARG A 1 71  ? -40.270 44.500  -21.991 1.00 26.40 ? 73  ARG A CG  1 
ATOM   531  C CD  . ARG A 1 71  ? -40.629 45.847  -21.412 1.00 35.61 ? 73  ARG A CD  1 
ATOM   532  N NE  . ARG A 1 71  ? -42.068 46.062  -21.342 1.00 36.83 ? 73  ARG A NE  1 
ATOM   533  C CZ  . ARG A 1 71  ? -42.740 46.900  -22.116 1.00 35.44 ? 73  ARG A CZ  1 
ATOM   534  N NH1 . ARG A 1 71  ? -42.131 47.613  -23.054 1.00 38.87 ? 73  ARG A NH1 1 
ATOM   535  N NH2 . ARG A 1 71  ? -44.053 47.023  -21.944 1.00 30.20 ? 73  ARG A NH2 1 
ATOM   536  N N   . TYR A 1 72  ? -39.311 44.516  -18.127 1.00 28.20 ? 74  TYR A N   1 
ATOM   537  C CA  . TYR A 1 72  ? -39.463 45.624  -17.193 1.00 29.33 ? 74  TYR A CA  1 
ATOM   538  C C   . TYR A 1 72  ? -39.173 46.914  -17.952 1.00 34.03 ? 74  TYR A C   1 
ATOM   539  O O   . TYR A 1 72  ? -38.035 47.114  -18.385 1.00 34.43 ? 74  TYR A O   1 
ATOM   540  C CB  . TYR A 1 72  ? -38.518 45.472  -16.002 1.00 28.99 ? 74  TYR A CB  1 
ATOM   541  C CG  . TYR A 1 72  ? -39.070 44.630  -14.863 1.00 28.28 ? 74  TYR A CG  1 
ATOM   542  C CD1 . TYR A 1 72  ? -39.020 43.241  -14.908 1.00 27.44 ? 74  TYR A CD1 1 
ATOM   543  C CD2 . TYR A 1 72  ? -39.585 45.226  -13.713 1.00 27.93 ? 74  TYR A CD2 1 
ATOM   544  C CE1 . TYR A 1 72  ? -39.514 42.470  -13.861 1.00 22.84 ? 74  TYR A CE1 1 
ATOM   545  C CE2 . TYR A 1 72  ? -40.072 44.457  -12.660 1.00 26.90 ? 74  TYR A CE2 1 
ATOM   546  C CZ  . TYR A 1 72  ? -40.039 43.080  -12.750 1.00 26.80 ? 74  TYR A CZ  1 
ATOM   547  O OH  . TYR A 1 72  ? -40.521 42.298  -11.737 1.00 25.64 ? 74  TYR A OH  1 
ATOM   548  N N   . PRO A 1 73  ? -40.148 47.793  -18.163 1.00 34.05 ? 75  PRO A N   1 
ATOM   549  C CA  . PRO A 1 73  ? -39.830 49.075  -18.791 1.00 38.08 ? 75  PRO A CA  1 
ATOM   550  C C   . PRO A 1 73  ? -38.896 49.864  -17.892 1.00 38.73 ? 75  PRO A C   1 
ATOM   551  O O   . PRO A 1 73  ? -38.873 49.685  -16.673 1.00 39.89 ? 75  PRO A O   1 
ATOM   552  C CB  . PRO A 1 73  ? -41.197 49.755  -18.953 1.00 37.19 ? 75  PRO A CB  1 
ATOM   553  C CG  . PRO A 1 73  ? -42.203 48.841  -18.294 1.00 37.20 ? 75  PRO A CG  1 
ATOM   554  C CD  . PRO A 1 73  ? -41.446 47.844  -17.478 1.00 36.04 ? 75  PRO A CD  1 
ATOM   555  N N   . ASP A 1 74  ? -38.095 50.730  -18.514 1.00 43.67 ? 76  ASP A N   1 
ATOM   556  C CA  . ASP A 1 74  ? -36.964 51.328  -17.808 1.00 45.41 ? 76  ASP A CA  1 
ATOM   557  C C   . ASP A 1 74  ? -37.378 52.176  -16.609 1.00 46.78 ? 76  ASP A C   1 
ATOM   558  O O   . ASP A 1 74  ? -36.595 52.299  -15.658 1.00 47.89 ? 76  ASP A O   1 
ATOM   559  C CB  . ASP A 1 74  ? -36.120 52.130  -18.792 1.00 50.54 ? 76  ASP A CB  1 
ATOM   560  C CG  . ASP A 1 74  ? -35.630 51.275  -19.949 1.00 55.08 ? 76  ASP A CG  1 
ATOM   561  O OD1 . ASP A 1 74  ? -36.472 50.825  -20.763 1.00 56.80 ? 76  ASP A OD1 1 
ATOM   562  O OD2 . ASP A 1 74  ? -34.406 51.030  -20.031 1.00 58.83 ? 76  ASP A OD2 1 
ATOM   563  N N   . HIS A 1 75  ? -38.598 52.722  -16.598 1.00 45.27 ? 77  HIS A N   1 
ATOM   564  C CA  . HIS A 1 75  ? -39.069 53.395  -15.392 1.00 45.61 ? 77  HIS A CA  1 
ATOM   565  C C   . HIS A 1 75  ? -39.292 52.425  -14.234 1.00 48.13 ? 77  HIS A C   1 
ATOM   566  O O   . HIS A 1 75  ? -39.533 52.877  -13.105 1.00 48.83 ? 77  HIS A O   1 
ATOM   567  C CB  . HIS A 1 75  ? -40.339 54.209  -15.696 1.00 49.32 ? 77  HIS A CB  1 
ATOM   568  C CG  . HIS A 1 75  ? -41.618 53.425  -15.655 1.00 51.86 ? 77  HIS A CG  1 
ATOM   569  N ND1 . HIS A 1 75  ? -42.334 53.221  -14.491 1.00 51.45 ? 77  HIS A ND1 1 
ATOM   570  C CD2 . HIS A 1 75  ? -42.329 52.829  -16.643 1.00 48.48 ? 77  HIS A CD2 1 
ATOM   571  C CE1 . HIS A 1 75  ? -43.426 52.527  -14.765 1.00 52.00 ? 77  HIS A CE1 1 
ATOM   572  N NE2 . HIS A 1 75  ? -43.444 52.272  -16.063 1.00 49.97 ? 77  HIS A NE2 1 
ATOM   573  N N   . MET A 1 76  ? -39.193 51.114  -14.475 1.00 43.34 ? 78  MET A N   1 
ATOM   574  C CA  . MET A 1 76  ? -39.167 50.132  -13.387 1.00 45.46 ? 78  MET A CA  1 
ATOM   575  C C   . MET A 1 76  ? -38.190 49.125  -13.994 1.00 44.23 ? 78  MET A C   1 
ATOM   576  O O   . MET A 1 76  ? -38.535 47.940  -14.073 1.00 40.53 ? 78  MET A O   1 
ATOM   577  C CB  . MET A 1 76  ? -40.411 49.238  -13.432 1.00 45.41 ? 78  MET A CB  1 
ATOM   578  C CG  . MET A 1 76  ? -41.659 49.884  -13.966 1.00 43.11 ? 78  MET A CG  1 
ATOM   579  S SD  . MET A 1 76  ? -42.944 48.644  -14.156 1.00 49.26 ? 78  MET A SD  1 
ATOM   580  C CE  . MET A 1 76  ? -43.269 48.280  -12.430 1.00 36.86 ? 78  MET A CE  1 
ATOM   581  N N   . LYS A 1 77  ? -36.987 49.524  -14.253 1.00 46.49 ? 79  LYS A N   1 
ATOM   582  C CA  . LYS A 1 77  ? -35.812 48.726  -14.183 1.00 46.98 ? 79  LYS A CA  1 
ATOM   583  C C   . LYS A 1 77  ? -34.970 48.674  -12.977 1.00 51.20 ? 79  LYS A C   1 
ATOM   584  O O   . LYS A 1 77  ? -33.769 48.436  -13.084 1.00 60.18 ? 79  LYS A O   1 
ATOM   585  C CB  . LYS A 1 77  ? -34.943 48.957  -15.399 1.00 45.89 ? 79  LYS A CB  1 
ATOM   586  C CG  . LYS A 1 77  ? -35.338 48.187  -16.560 1.00 43.32 ? 79  LYS A CG  1 
ATOM   587  C CD  . LYS A 1 77  ? -34.566 48.705  -17.706 1.00 48.82 ? 79  LYS A CD  1 
ATOM   588  C CE  . LYS A 1 77  ? -34.826 47.866  -18.916 1.00 51.37 ? 79  LYS A CE  1 
ATOM   589  N NZ  . LYS A 1 77  ? -33.587 47.670  -19.717 1.00 59.33 ? 79  LYS A NZ  1 
ATOM   590  N N   . ARG A 1 78  ? -35.597 48.920  -11.842 1.00 46.32 ? 80  ARG A N   1 
ATOM   591  C CA  . ARG A 1 78  ? -34.999 49.183  -10.546 1.00 46.02 ? 80  ARG A CA  1 
ATOM   592  C C   . ARG A 1 78  ? -35.829 48.315  -9.632  1.00 44.54 ? 80  ARG A C   1 
ATOM   593  O O   . ARG A 1 78  ? -35.423 47.873  -8.592  1.00 43.59 ? 80  ARG A O   1 
ATOM   594  C CB  . ARG A 1 78  ? -34.908 50.659  -10.208 1.00 49.82 ? 80  ARG A CB  1 
ATOM   595  C CG  . ARG A 1 78  ? -35.923 51.086  -9.187  1.00 51.85 ? 80  ARG A CG  1 
ATOM   596  C CD  . ARG A 1 78  ? -37.076 51.668  -9.932  1.00 54.09 ? 80  ARG A CD  1 
ATOM   597  N NE  . ARG A 1 78  ? -37.027 53.116  -9.894  1.00 57.39 ? 80  ARG A NE  1 
ATOM   598  C CZ  . ARG A 1 78  ? -37.444 53.841  -8.870  1.00 57.21 ? 80  ARG A CZ  1 
ATOM   599  N NH1 . ARG A 1 78  ? -37.953 53.256  -7.804  1.00 53.90 ? 80  ARG A NH1 1 
ATOM   600  N NH2 . ARG A 1 78  ? -37.347 55.155  -8.917  1.00 57.22 ? 80  ARG A NH2 1 
ATOM   601  N N   . HIS A 1 79  ? -37.016 48.004  -10.104 1.00 44.00 ? 81  HIS A N   1 
ATOM   602  C CA  . HIS A 1 79  ? -37.867 47.092  -9.357  1.00 37.97 ? 81  HIS A CA  1 
ATOM   603  C C   . HIS A 1 79  ? -37.773 45.629  -9.781  1.00 32.63 ? 81  HIS A C   1 
ATOM   604  O O   . HIS A 1 79  ? -38.637 44.818  -9.425  1.00 32.57 ? 81  HIS A O   1 
ATOM   605  C CB  . HIS A 1 79  ? -39.295 47.619  -9.485  1.00 40.32 ? 81  HIS A CB  1 
ATOM   606  C CG  . HIS A 1 79  ? -39.539 48.866  -8.693  1.00 45.42 ? 81  HIS A CG  1 
ATOM   607  N ND1 . HIS A 1 79  ? -39.668 48.870  -7.320  1.00 47.83 ? 81  HIS A ND1 1 
ATOM   608  C CD2 . HIS A 1 79  ? -39.658 50.157  -9.085  1.00 47.44 ? 81  HIS A CD2 1 
ATOM   609  C CE1 . HIS A 1 79  ? -39.857 50.109  -6.901  1.00 48.72 ? 81  HIS A CE1 1 
ATOM   610  N NE2 . HIS A 1 79  ? -39.860 50.908  -7.953  1.00 45.49 ? 81  HIS A NE2 1 
ATOM   611  N N   . ASP A 1 80  ? -36.722 45.279  -10.530 1.00 33.53 ? 82  ASP A N   1 
ATOM   612  C CA  . ASP A 1 80  ? -36.569 43.954  -11.134 1.00 27.33 ? 82  ASP A CA  1 
ATOM   613  C C   . ASP A 1 80  ? -35.683 43.088  -10.241 1.00 23.19 ? 82  ASP A C   1 
ATOM   614  O O   . ASP A 1 80  ? -34.475 42.953  -10.444 1.00 21.72 ? 82  ASP A O   1 
ATOM   615  C CB  . ASP A 1 80  ? -36.005 44.093  -12.540 1.00 25.21 ? 82  ASP A CB  1 
ATOM   616  C CG  . ASP A 1 80  ? -36.011 42.788  -13.311 1.00 25.20 ? 82  ASP A CG  1 
ATOM   617  O OD1 . ASP A 1 80  ? -36.335 41.736  -12.720 1.00 20.60 ? 82  ASP A OD1 1 
ATOM   618  O OD2 . ASP A 1 80  ? -35.727 42.839  -14.529 1.00 25.26 ? 82  ASP A OD2 1 
ATOM   619  N N   . PHE A 1 81  ? -36.323 42.473  -9.245  1.00 21.40 ? 83  PHE A N   1 
ATOM   620  C CA  . PHE A 1 81  ? -35.633 41.549  -8.353  1.00 24.72 ? 83  PHE A CA  1 
ATOM   621  C C   . PHE A 1 81  ? -35.018 40.390  -9.130  1.00 22.70 ? 83  PHE A C   1 
ATOM   622  O O   . PHE A 1 81  ? -33.881 39.981  -8.860  1.00 20.23 ? 83  PHE A O   1 
ATOM   623  C CB  . PHE A 1 81  ? -36.618 41.026  -7.294  1.00 22.28 ? 83  PHE A CB  1 
ATOM   624  C CG  . PHE A 1 81  ? -36.195 39.737  -6.644  1.00 26.49 ? 83  PHE A CG  1 
ATOM   625  C CD1 . PHE A 1 81  ? -35.373 39.752  -5.535  1.00 26.79 ? 83  PHE A CD1 1 
ATOM   626  C CD2 . PHE A 1 81  ? -36.630 38.510  -7.130  1.00 23.12 ? 83  PHE A CD2 1 
ATOM   627  C CE1 . PHE A 1 81  ? -34.968 38.574  -4.927  1.00 24.29 ? 83  PHE A CE1 1 
ATOM   628  C CE2 . PHE A 1 81  ? -36.236 37.326  -6.535  1.00 21.92 ? 83  PHE A CE2 1 
ATOM   629  C CZ  . PHE A 1 81  ? -35.403 37.350  -5.428  1.00 25.98 ? 83  PHE A CZ  1 
ATOM   630  N N   . PHE A 1 82  ? -35.755 39.864  -10.109 1.00 19.56 ? 84  PHE A N   1 
ATOM   631  C CA  . PHE A 1 82  ? -35.390 38.601  -10.749 1.00 21.71 ? 84  PHE A CA  1 
ATOM   632  C C   . PHE A 1 82  ? -34.067 38.711  -11.498 1.00 18.24 ? 84  PHE A C   1 
ATOM   633  O O   . PHE A 1 82  ? -33.212 37.824  -11.398 1.00 18.29 ? 84  PHE A O   1 
ATOM   634  C CB  . PHE A 1 82  ? -36.502 38.160  -11.704 1.00 16.83 ? 84  PHE A CB  1 
ATOM   635  C CG  . PHE A 1 82  ? -37.863 38.055  -11.059 1.00 16.39 ? 84  PHE A CG  1 
ATOM   636  C CD1 . PHE A 1 82  ? -38.186 36.970  -10.267 1.00 17.43 ? 84  PHE A CD1 1 
ATOM   637  C CD2 . PHE A 1 82  ? -38.828 39.029  -11.278 1.00 19.17 ? 84  PHE A CD2 1 
ATOM   638  C CE1 . PHE A 1 82  ? -39.443 36.859  -9.677  1.00 21.16 ? 84  PHE A CE1 1 
ATOM   639  C CE2 . PHE A 1 82  ? -40.092 38.929  -10.696 1.00 18.99 ? 84  PHE A CE2 1 
ATOM   640  C CZ  . PHE A 1 82  ? -40.395 37.847  -9.891  1.00 17.36 ? 84  PHE A CZ  1 
ATOM   641  N N   . LYS A 1 83  ? -33.900 39.765  -12.298 1.00 17.15 ? 85  LYS A N   1 
ATOM   642  C CA  . LYS A 1 83  ? -32.629 39.941  -12.989 1.00 20.24 ? 85  LYS A CA  1 
ATOM   643  C C   . LYS A 1 83  ? -31.518 40.329  -12.023 1.00 23.34 ? 85  LYS A C   1 
ATOM   644  O O   . LYS A 1 83  ? -30.364 39.941  -12.223 1.00 22.03 ? 85  LYS A O   1 
ATOM   645  C CB  . LYS A 1 83  ? -32.746 40.993  -14.092 1.00 19.71 ? 85  LYS A CB  1 
ATOM   646  C CG  . LYS A 1 83  ? -33.658 40.603  -15.235 1.00 21.70 ? 85  LYS A CG  1 
ATOM   647  C CD  . LYS A 1 83  ? -33.573 41.611  -16.374 1.00 22.74 ? 85  LYS A CD  1 
ATOM   648  C CE  . LYS A 1 83  ? -34.668 41.407  -17.418 1.00 21.36 ? 85  LYS A CE  1 
ATOM   649  N NZ  . LYS A 1 83  ? -36.026 41.336  -16.798 1.00 21.42 ? 85  LYS A NZ  1 
ATOM   650  N N   . SER A 1 84  ? -31.848 41.081  -10.972 1.00 21.22 ? 86  SER A N   1 
ATOM   651  C CA  . SER A 1 84  ? -30.818 41.577  -10.069 1.00 24.16 ? 86  SER A CA  1 
ATOM   652  C C   . SER A 1 84  ? -30.105 40.440  -9.345  1.00 23.20 ? 86  SER A C   1 
ATOM   653  O O   . SER A 1 84  ? -28.908 40.556  -9.043  1.00 23.15 ? 86  SER A O   1 
ATOM   654  C CB  . SER A 1 84  ? -31.439 42.570  -9.077  1.00 26.80 ? 86  SER A CB  1 
ATOM   655  O OG  . SER A 1 84  ? -31.808 41.939  -7.859  1.00 28.49 ? 86  SER A OG  1 
ATOM   656  N N   . ALA A 1 85  ? -30.815 39.344  -9.071  1.00 20.24 ? 87  ALA A N   1 
ATOM   657  C CA  . ALA A 1 85  ? -30.250 38.180  -8.406  1.00 21.33 ? 87  ALA A CA  1 
ATOM   658  C C   . ALA A 1 85  ? -29.301 37.372  -9.291  1.00 18.26 ? 87  ALA A C   1 
ATOM   659  O O   . ALA A 1 85  ? -28.589 36.518  -8.758  1.00 19.95 ? 87  ALA A O   1 
ATOM   660  C CB  . ALA A 1 85  ? -31.375 37.273  -7.896  1.00 18.88 ? 87  ALA A CB  1 
ATOM   661  N N   . MET A 1 86  ? -29.291 37.589  -10.613 1.00 21.52 ? 88  MET A N   1 
ATOM   662  C CA  . MET A 1 86  ? -28.349 36.935  -11.532 1.00 21.00 ? 88  MET A CA  1 
ATOM   663  C C   . MET A 1 86  ? -26.926 37.478  -11.421 1.00 22.09 ? 88  MET A C   1 
ATOM   664  O O   . MET A 1 86  ? -26.724 38.650  -11.109 1.00 24.13 ? 88  MET A O   1 
ATOM   665  C CB  . MET A 1 86  ? -28.832 37.054  -12.983 1.00 19.55 ? 88  MET A CB  1 
ATOM   666  C CG  . MET A 1 86  ? -30.169 36.380  -13.370 1.00 18.32 ? 88  MET A CG  1 
ATOM   667  S SD  . MET A 1 86  ? -30.320 34.714  -12.637 1.00 17.01 ? 88  MET A SD  1 
ATOM   668  C CE  . MET A 1 86  ? -32.040 34.418  -12.302 1.00 15.07 ? 88  MET A CE  1 
ATOM   669  N N   . PRO A 1 87  ? -25.905 36.639  -11.730 1.00 21.93 ? 89  PRO A N   1 
ATOM   670  C CA  . PRO A 1 87  ? -26.003 35.256  -12.233 1.00 18.93 ? 89  PRO A CA  1 
ATOM   671  C C   . PRO A 1 87  ? -26.242 34.198  -11.168 1.00 20.96 ? 89  PRO A C   1 
ATOM   672  O O   . PRO A 1 87  ? -26.620 33.071  -11.513 1.00 19.82 ? 89  PRO A O   1 
ATOM   673  C CB  . PRO A 1 87  ? -24.636 35.030  -12.889 1.00 19.04 ? 89  PRO A CB  1 
ATOM   674  C CG  . PRO A 1 87  ? -23.704 35.856  -12.069 1.00 20.56 ? 89  PRO A CG  1 
ATOM   675  C CD  . PRO A 1 87  ? -24.505 37.105  -11.707 1.00 23.98 ? 89  PRO A CD  1 
ATOM   676  N N   . GLU A 1 88  ? -26.008 34.531  -9.893  1.00 20.14 ? 90  GLU A N   1 
ATOM   677  C CA  . GLU A 1 88  ? -26.106 33.521  -8.841  1.00 17.58 ? 90  GLU A CA  1 
ATOM   678  C C   . GLU A 1 88  ? -27.506 32.933  -8.745  1.00 19.71 ? 90  GLU A C   1 
ATOM   679  O O   . GLU A 1 88  ? -27.658 31.744  -8.444  1.00 17.85 ? 90  GLU A O   1 
ATOM   680  C CB  . GLU A 1 88  ? -25.678 34.125  -7.505  1.00 24.28 ? 90  GLU A CB  1 
ATOM   681  C CG  . GLU A 1 88  ? -24.313 34.792  -7.579  1.00 28.70 ? 90  GLU A CG  1 
ATOM   682  C CD  . GLU A 1 88  ? -24.411 36.308  -7.564  1.00 36.13 ? 90  GLU A CD  1 
ATOM   683  O OE1 . GLU A 1 88  ? -25.035 36.886  -8.497  1.00 26.89 ? 90  GLU A OE1 1 
ATOM   684  O OE2 . GLU A 1 88  ? -23.867 36.918  -6.614  1.00 42.96 ? 90  GLU A OE2 1 
ATOM   685  N N   . GLY A 1 89  ? -28.532 33.736  -9.004  1.00 20.03 ? 91  GLY A N   1 
ATOM   686  C CA  . GLY A 1 89  ? -29.880 33.219  -9.155  1.00 15.44 ? 91  GLY A CA  1 
ATOM   687  C C   . GLY A 1 89  ? -30.753 33.394  -7.929  1.00 20.93 ? 91  GLY A C   1 
ATOM   688  O O   . GLY A 1 89  ? -30.433 34.106  -6.972  1.00 18.63 ? 91  GLY A O   1 
ATOM   689  N N   . TYR A 1 90  ? -31.908 32.733  -7.985  1.00 13.99 ? 92  TYR A N   1 
ATOM   690  C CA  . TYR A 1 90  ? -32.874 32.778  -6.903  1.00 17.59 ? 92  TYR A CA  1 
ATOM   691  C C   . TYR A 1 90  ? -33.557 31.430  -6.780  1.00 17.59 ? 92  TYR A C   1 
ATOM   692  O O   . TYR A 1 90  ? -33.619 30.644  -7.735  1.00 16.65 ? 92  TYR A O   1 
ATOM   693  C CB  . TYR A 1 90  ? -33.912 33.905  -7.110  1.00 17.12 ? 92  TYR A CB  1 
ATOM   694  C CG  . TYR A 1 90  ? -34.694 33.872  -8.422  1.00 14.52 ? 92  TYR A CG  1 
ATOM   695  C CD1 . TYR A 1 90  ? -35.800 33.040  -8.593  1.00 15.89 ? 92  TYR A CD1 1 
ATOM   696  C CD2 . TYR A 1 90  ? -34.363 34.728  -9.452  1.00 15.93 ? 92  TYR A CD2 1 
ATOM   697  C CE1 . TYR A 1 90  ? -36.519 33.030  -9.791  1.00 14.96 ? 92  TYR A CE1 1 
ATOM   698  C CE2 . TYR A 1 90  ? -35.064 34.730  -10.638 1.00 15.92 ? 92  TYR A CE2 1 
ATOM   699  C CZ  . TYR A 1 90  ? -36.144 33.884  -10.802 1.00 14.42 ? 92  TYR A CZ  1 
ATOM   700  O OH  . TYR A 1 90  ? -36.827 33.929  -12.005 1.00 14.39 ? 92  TYR A OH  1 
ATOM   701  N N   . VAL A 1 91  ? -34.064 31.163  -5.576  1.00 15.56 ? 93  VAL A N   1 
ATOM   702  C CA  . VAL A 1 91  ? -34.896 30.004  -5.311  1.00 15.60 ? 93  VAL A CA  1 
ATOM   703  C C   . VAL A 1 91  ? -36.335 30.443  -5.518  1.00 18.38 ? 93  VAL A C   1 
ATOM   704  O O   . VAL A 1 91  ? -36.712 31.551  -5.114  1.00 17.24 ? 93  VAL A O   1 
ATOM   705  C CB  . VAL A 1 91  ? -34.673 29.476  -3.879  1.00 18.82 ? 93  VAL A CB  1 
ATOM   706  C CG1 . VAL A 1 91  ? -35.708 28.412  -3.523  1.00 18.21 ? 93  VAL A CG1 1 
ATOM   707  C CG2 . VAL A 1 91  ? -33.264 28.942  -3.709  1.00 18.86 ? 93  VAL A CG2 1 
ATOM   708  N N   . GLN A 1 92  ? -37.137 29.597  -6.171  1.00 16.08 ? 94  GLN A N   1 
ATOM   709  C CA  . GLN A 1 92  ? -38.565 29.841  -6.355  1.00 14.78 ? 94  GLN A CA  1 
ATOM   710  C C   . GLN A 1 92  ? -39.337 28.679  -5.764  1.00 17.46 ? 94  GLN A C   1 
ATOM   711  O O   . GLN A 1 92  ? -39.187 27.537  -6.218  1.00 15.61 ? 94  GLN A O   1 
ATOM   712  C CB  . GLN A 1 92  ? -38.938 30.008  -7.833  1.00 17.44 ? 94  GLN A CB  1 
ATOM   713  C CG  . GLN A 1 92  ? -40.403 30.423  -8.012  1.00 13.67 ? 94  GLN A CG  1 
ATOM   714  C CD  . GLN A 1 92  ? -40.666 31.043  -9.360  1.00 14.85 ? 94  GLN A CD  1 
ATOM   715  O OE1 . GLN A 1 92  ? -40.210 32.154  -9.637  1.00 15.21 ? 94  GLN A OE1 1 
ATOM   716  N NE2 . GLN A 1 92  ? -41.450 30.355  -10.189 1.00 16.65 ? 94  GLN A NE2 1 
ATOM   717  N N   . GLU A 1 93  ? -40.163 28.974  -4.764  1.00 15.94 ? 95  GLU A N   1 
ATOM   718  C CA  . GLU A 1 93  ? -40.974 27.985  -4.070  1.00 16.04 ? 95  GLU A CA  1 
ATOM   719  C C   . GLU A 1 93  ? -42.451 28.296  -4.282  1.00 16.42 ? 95  GLU A C   1 
ATOM   720  O O   . GLU A 1 93  ? -42.855 29.456  -4.197  1.00 16.48 ? 95  GLU A O   1 
ATOM   721  C CB  . GLU A 1 93  ? -40.654 27.989  -2.569  1.00 19.00 ? 95  GLU A CB  1 
ATOM   722  C CG  . GLU A 1 93  ? -39.379 27.230  -2.203  1.00 19.46 ? 95  GLU A CG  1 
ATOM   723  C CD  . GLU A 1 93  ? -38.811 27.622  -0.838  1.00 29.07 ? 95  GLU A CD  1 
ATOM   724  O OE1 . GLU A 1 93  ? -39.067 28.742  -0.343  1.00 29.79 ? 95  GLU A OE1 1 
ATOM   725  O OE2 . GLU A 1 93  ? -38.145 26.769  -0.233  1.00 37.77 ? 95  GLU A OE2 1 
ATOM   726  N N   . ARG A 1 94  ? -43.254 27.262  -4.546  1.00 14.49 ? 96  ARG A N   1 
ATOM   727  C CA  . ARG A 1 94  ? -44.699 27.423  -4.635  1.00 16.36 ? 96  ARG A CA  1 
ATOM   728  C C   . ARG A 1 94  ? -45.407 26.242  -3.981  1.00 15.05 ? 96  ARG A C   1 
ATOM   729  O O   . ARG A 1 94  ? -44.878 25.129  -3.912  1.00 17.66 ? 96  ARG A O   1 
ATOM   730  C CB  . ARG A 1 94  ? -45.182 27.546  -6.100  1.00 13.33 ? 96  ARG A CB  1 
ATOM   731  C CG  . ARG A 1 94  ? -44.805 28.833  -6.786  1.00 13.17 ? 96  ARG A CG  1 
ATOM   732  C CD  . ARG A 1 94  ? -45.886 29.258  -7.792  1.00 13.54 ? 96  ARG A CD  1 
ATOM   733  N NE  . ARG A 1 94  ? -45.465 30.362  -8.648  1.00 16.47 ? 96  ARG A NE  1 
ATOM   734  C CZ  . ARG A 1 94  ? -44.918 30.223  -9.849  1.00 14.19 ? 96  ARG A CZ  1 
ATOM   735  N NH1 . ARG A 1 94  ? -44.634 29.024  -10.345 1.00 13.07 ? 96  ARG A NH1 1 
ATOM   736  N NH2 . ARG A 1 94  ? -44.643 31.312  -10.566 1.00 12.82 ? 96  ARG A NH2 1 
ATOM   737  N N   . THR A 1 95  ? -46.611 26.503  -3.482  1.00 14.66 ? 97  THR A N   1 
ATOM   738  C CA  . THR A 1 95  ? -47.625 25.482  -3.288  1.00 13.62 ? 97  THR A CA  1 
ATOM   739  C C   . THR A 1 95  ? -48.810 25.855  -4.160  1.00 14.44 ? 97  THR A C   1 
ATOM   740  O O   . THR A 1 95  ? -49.224 27.021  -4.182  1.00 16.73 ? 97  THR A O   1 
ATOM   741  C CB  . THR A 1 95  ? -48.060 25.341  -1.821  1.00 16.36 ? 97  THR A CB  1 
ATOM   742  O OG1 . THR A 1 95  ? -46.901 25.094  -1.019  1.00 17.01 ? 97  THR A OG1 1 
ATOM   743  C CG2 . THR A 1 95  ? -49.029 24.167  -1.656  1.00 16.29 ? 97  THR A CG2 1 
ATOM   744  N N   . ILE A 1 96  ? -49.317 24.877  -4.898  1.00 14.32 ? 98  ILE A N   1 
ATOM   745  C CA  . ILE A 1 96  ? -50.414 25.056  -5.842  1.00 13.68 ? 98  ILE A CA  1 
ATOM   746  C C   . ILE A 1 96  ? -51.510 24.090  -5.422  1.00 15.66 ? 98  ILE A C   1 
ATOM   747  O O   . ILE A 1 96  ? -51.357 22.867  -5.555  1.00 15.17 ? 98  ILE A O   1 
ATOM   748  C CB  . ILE A 1 96  ? -49.984 24.810  -7.300  1.00 12.43 ? 98  ILE A CB  1 
ATOM   749  C CG1 . ILE A 1 96  ? -48.794 25.689  -7.702  1.00 12.79 ? 98  ILE A CG1 1 
ATOM   750  C CG2 . ILE A 1 96  ? -51.168 25.041  -8.248  1.00 14.84 ? 98  ILE A CG2 1 
ATOM   751  C CD1 . ILE A 1 96  ? -48.159 25.281  -9.072  1.00 12.92 ? 98  ILE A CD1 1 
ATOM   752  N N   . PHE A 1 97  ? -52.609 24.634  -4.905  1.00 13.26 ? 99  PHE A N   1 
ATOM   753  C CA  . PHE A 1 97  ? -53.744 23.847  -4.443  1.00 16.34 ? 99  PHE A CA  1 
ATOM   754  C C   . PHE A 1 97  ? -54.771 23.729  -5.557  1.00 16.50 ? 99  PHE A C   1 
ATOM   755  O O   . PHE A 1 97  ? -55.324 24.745  -5.992  1.00 15.76 ? 99  PHE A O   1 
ATOM   756  C CB  . PHE A 1 97  ? -54.397 24.524  -3.239  1.00 18.05 ? 99  PHE A CB  1 
ATOM   757  C CG  . PHE A 1 97  ? -53.565 24.525  -1.997  1.00 16.78 ? 99  PHE A CG  1 
ATOM   758  C CD1 . PHE A 1 97  ? -53.531 23.417  -1.170  1.00 18.31 ? 99  PHE A CD1 1 
ATOM   759  C CD2 . PHE A 1 97  ? -52.829 25.648  -1.647  1.00 16.48 ? 99  PHE A CD2 1 
ATOM   760  C CE1 . PHE A 1 97  ? -52.781 23.430  0.007   1.00 19.09 ? 99  PHE A CE1 1 
ATOM   761  C CE2 . PHE A 1 97  ? -52.076 25.664  -0.478  1.00 18.78 ? 99  PHE A CE2 1 
ATOM   762  C CZ  . PHE A 1 97  ? -52.053 24.557  0.341   1.00 16.96 ? 99  PHE A CZ  1 
ATOM   763  N N   . PHE A 1 98  ? -55.047 22.504  -5.997  1.00 17.18 ? 100 PHE A N   1 
ATOM   764  C CA  . PHE A 1 98  ? -56.093 22.257  -6.982  1.00 18.72 ? 100 PHE A CA  1 
ATOM   765  C C   . PHE A 1 98  ? -57.403 22.021  -6.237  1.00 21.43 ? 100 PHE A C   1 
ATOM   766  O O   . PHE A 1 98  ? -57.501 21.102  -5.411  1.00 19.68 ? 100 PHE A O   1 
ATOM   767  C CB  . PHE A 1 98  ? -55.721 21.074  -7.874  1.00 17.30 ? 100 PHE A CB  1 
ATOM   768  C CG  . PHE A 1 98  ? -54.561 21.364  -8.784  1.00 18.03 ? 100 PHE A CG  1 
ATOM   769  C CD1 . PHE A 1 98  ? -54.757 21.942  -10.026 1.00 15.80 ? 100 PHE A CD1 1 
ATOM   770  C CD2 . PHE A 1 98  ? -53.263 21.124  -8.360  1.00 18.08 ? 100 PHE A CD2 1 
ATOM   771  C CE1 . PHE A 1 98  ? -53.675 22.246  -10.850 1.00 16.44 ? 100 PHE A CE1 1 
ATOM   772  C CE2 . PHE A 1 98  ? -52.176 21.425  -9.178  1.00 15.65 ? 100 PHE A CE2 1 
ATOM   773  C CZ  . PHE A 1 98  ? -52.383 21.989  -10.419 1.00 15.56 ? 100 PHE A CZ  1 
ATOM   774  N N   . LYS A 1 99  ? -58.389 22.872  -6.504  1.00 20.17 ? 101 LYS A N   1 
ATOM   775  C CA  . LYS A 1 99  ? -59.670 22.813  -5.812  1.00 22.01 ? 101 LYS A CA  1 
ATOM   776  C C   . LYS A 1 99  ? -60.283 21.422  -5.898  1.00 24.66 ? 101 LYS A C   1 
ATOM   777  O O   . LYS A 1 99  ? -60.333 20.822  -6.972  1.00 22.03 ? 101 LYS A O   1 
ATOM   778  C CB  . LYS A 1 99  ? -60.637 23.850  -6.387  1.00 23.21 ? 101 LYS A CB  1 
ATOM   779  C CG  . LYS A 1 99  ? -61.306 24.724  -5.338  1.00 30.66 ? 101 LYS A CG  1 
ATOM   780  C CD  . LYS A 1 99  ? -62.759 24.327  -5.133  1.00 35.26 ? 101 LYS A CD  1 
ATOM   781  C CE  . LYS A 1 99  ? -63.299 24.870  -3.820  1.00 39.42 ? 101 LYS A CE  1 
ATOM   782  N NZ  . LYS A 1 99  ? -64.782 25.000  -3.841  1.00 42.49 ? 101 LYS A NZ  1 
ATOM   783  N N   . ASP A 1 100 ? -60.750 20.914  -4.763  1.00 22.41 ? 102 ASP A N   1 
ATOM   784  C CA  . ASP A 1 100 ? -61.368 19.590  -4.729  1.00 23.63 ? 102 ASP A CA  1 
ATOM   785  C C   . ASP A 1 100 ? -60.418 18.489  -5.200  1.00 24.45 ? 102 ASP A C   1 
ATOM   786  O O   . ASP A 1 100 ? -60.862 17.426  -5.631  1.00 24.47 ? 102 ASP A O   1 
ATOM   787  C CB  . ASP A 1 100 ? -62.665 19.565  -5.542  1.00 25.89 ? 102 ASP A CB  1 
ATOM   788  C CG  . ASP A 1 100 ? -63.683 20.579  -5.041  1.00 33.43 ? 102 ASP A CG  1 
ATOM   789  O OD1 . ASP A 1 100 ? -63.638 20.908  -3.835  1.00 33.67 ? 102 ASP A OD1 1 
ATOM   790  O OD2 . ASP A 1 100 ? -64.506 21.067  -5.849  1.00 41.13 ? 102 ASP A OD2 1 
ATOM   791  N N   . ASP A 1 101 ? -59.111 18.718  -5.108  1.00 20.97 ? 103 ASP A N   1 
ATOM   792  C CA  . ASP A 1 101 ? -58.121 17.730  -5.546  1.00 21.21 ? 103 ASP A CA  1 
ATOM   793  C C   . ASP A 1 101 ? -56.831 17.963  -4.764  1.00 21.40 ? 103 ASP A C   1 
ATOM   794  O O   . ASP A 1 101 ? -56.849 18.603  -3.708  1.00 22.22 ? 103 ASP A O   1 
ATOM   795  C CB  . ASP A 1 101 ? -57.918 17.793  -7.072  1.00 18.85 ? 103 ASP A CB  1 
ATOM   796  C CG  . ASP A 1 101 ? -57.615 16.429  -7.671  1.00 22.36 ? 103 ASP A CG  1 
ATOM   797  O OD1 . ASP A 1 101 ? -56.938 15.638  -6.988  1.00 22.07 ? 103 ASP A OD1 1 
ATOM   798  O OD2 . ASP A 1 101 ? -58.044 16.144  -8.813  1.00 23.35 ? 103 ASP A OD2 1 
ATOM   799  N N   . GLY A 1 102 ? -55.715 17.431  -5.268  1.00 22.18 ? 104 GLY A N   1 
ATOM   800  C CA  . GLY A 1 102 ? -54.461 17.475  -4.546  1.00 19.58 ? 104 GLY A CA  1 
ATOM   801  C C   . GLY A 1 102 ? -53.719 18.785  -4.745  1.00 17.28 ? 104 GLY A C   1 
ATOM   802  O O   . GLY A 1 102 ? -54.238 19.754  -5.300  1.00 19.32 ? 104 GLY A O   1 
ATOM   803  N N   . ASN A 1 103 ? -52.459 18.796  -4.309  1.00 16.86 ? 105 ASN A N   1 
ATOM   804  C CA  . ASN A 1 103 ? -51.624 19.985  -4.419  1.00 17.46 ? 105 ASN A CA  1 
ATOM   805  C C   . ASN A 1 103 ? -50.226 19.624  -4.912  1.00 19.40 ? 105 ASN A C   1 
ATOM   806  O O   . ASN A 1 103 ? -49.722 18.525  -4.664  1.00 17.73 ? 105 ASN A O   1 
ATOM   807  C CB  . ASN A 1 103 ? -51.521 20.729  -3.083  1.00 16.52 ? 105 ASN A CB  1 
ATOM   808  C CG  . ASN A 1 103 ? -50.757 19.931  -2.024  1.00 25.24 ? 105 ASN A CG  1 
ATOM   809  O OD1 . ASN A 1 103 ? -49.546 20.098  -1.848  1.00 20.84 ? 105 ASN A OD1 1 
ATOM   810  N ND2 . ASN A 1 103 ? -51.472 19.074  -1.308  1.00 22.15 ? 105 ASN A ND2 1 
ATOM   811  N N   . TYR A 1 104 ? -49.614 20.566  -5.627  1.00 15.30 ? 106 TYR A N   1 
ATOM   812  C CA  . TYR A 1 104 ? -48.200 20.515  -5.983  1.00 17.09 ? 106 TYR A CA  1 
ATOM   813  C C   . TYR A 1 104 ? -47.412 21.380  -5.012  1.00 17.13 ? 106 TYR A C   1 
ATOM   814  O O   . TYR A 1 104 ? -47.821 22.500  -4.701  1.00 16.74 ? 106 TYR A O   1 
ATOM   815  C CB  . TYR A 1 104 ? -47.926 21.061  -7.397  1.00 13.76 ? 106 TYR A CB  1 
ATOM   816  C CG  . TYR A 1 104 ? -48.552 20.382  -8.604  1.00 11.83 ? 106 TYR A CG  1 
ATOM   817  C CD1 . TYR A 1 104 ? -48.997 19.068  -8.570  1.00 14.63 ? 106 TYR A CD1 1 
ATOM   818  C CD2 . TYR A 1 104 ? -48.660 21.080  -9.811  1.00 15.67 ? 106 TYR A CD2 1 
ATOM   819  C CE1 . TYR A 1 104 ? -49.557 18.477  -9.697  1.00 16.41 ? 106 TYR A CE1 1 
ATOM   820  C CE2 . TYR A 1 104 ? -49.215 20.509  -10.931 1.00 14.36 ? 106 TYR A CE2 1 
ATOM   821  C CZ  . TYR A 1 104 ? -49.656 19.205  -10.882 1.00 16.55 ? 106 TYR A CZ  1 
ATOM   822  O OH  . TYR A 1 104 ? -50.209 18.629  -12.017 1.00 15.51 ? 106 TYR A OH  1 
ATOM   823  N N   . LYS A 1 105 ? -46.259 20.889  -4.569  1.00 13.79 ? 107 LYS A N   1 
ATOM   824  C CA  . LYS A 1 105 ? -45.259 21.736  -3.934  1.00 16.00 ? 107 LYS A CA  1 
ATOM   825  C C   . LYS A 1 105 ? -44.049 21.738  -4.860  1.00 18.40 ? 107 LYS A C   1 
ATOM   826  O O   . LYS A 1 105 ? -43.644 20.673  -5.333  1.00 15.66 ? 107 LYS A O   1 
ATOM   827  C CB  . LYS A 1 105 ? -44.900 21.227  -2.526  1.00 18.93 ? 107 LYS A CB  1 
ATOM   828  C CG  . LYS A 1 105 ? -46.130 21.133  -1.585  1.00 20.68 ? 107 LYS A CG  1 
ATOM   829  C CD  . LYS A 1 105 ? -45.837 21.454  -0.114  1.00 30.33 ? 107 LYS A CD  1 
ATOM   830  C CE  . LYS A 1 105 ? -47.113 21.987  0.676   1.00 33.59 ? 107 LYS A CE  1 
ATOM   831  N NZ  . LYS A 1 105 ? -48.396 21.120  0.622   1.00 23.09 ? 107 LYS A NZ  1 
ATOM   832  N N   . THR A 1 106 ? -43.514 22.925  -5.168  1.00 15.47 ? 108 THR A N   1 
ATOM   833  C CA  . THR A 1 106 ? -42.411 23.039  -6.115  1.00 16.30 ? 108 THR A CA  1 
ATOM   834  C C   . THR A 1 106 ? -41.274 23.837  -5.503  1.00 15.27 ? 108 THR A C   1 
ATOM   835  O O   . THR A 1 106 ? -41.498 24.850  -4.839  1.00 13.60 ? 108 THR A O   1 
ATOM   836  C CB  . THR A 1 106 ? -42.821 23.712  -7.451  1.00 14.64 ? 108 THR A CB  1 
ATOM   837  O OG1 . THR A 1 106 ? -43.191 25.079  -7.237  1.00 15.16 ? 108 THR A OG1 1 
ATOM   838  C CG2 . THR A 1 106 ? -43.983 22.979  -8.078  1.00 14.76 ? 108 THR A CG2 1 
ATOM   839  N N   . ARG A 1 107 ? -40.051 23.359  -5.717  1.00 15.94 ? 109 ARG A N   1 
ATOM   840  C CA  . ARG A 1 107 ? -38.852 24.095  -5.365  1.00 17.11 ? 109 ARG A CA  1 
ATOM   841  C C   . ARG A 1 107 ? -37.969 24.161  -6.599  1.00 17.14 ? 109 ARG A C   1 
ATOM   842  O O   . ARG A 1 107 ? -37.652 23.126  -7.197  1.00 16.88 ? 109 ARG A O   1 
ATOM   843  C CB  . ARG A 1 107 ? -38.070 23.441  -4.211  1.00 15.78 ? 109 ARG A CB  1 
ATOM   844  C CG  . ARG A 1 107 ? -37.012 24.382  -3.646  1.00 18.13 ? 109 ARG A CG  1 
ATOM   845  C CD  . ARG A 1 107 ? -36.165 23.744  -2.541  1.00 19.93 ? 109 ARG A CD  1 
ATOM   846  N NE  . ARG A 1 107 ? -35.081 24.634  -2.128  1.00 21.28 ? 109 ARG A NE  1 
ATOM   847  C CZ  . ARG A 1 107 ? -33.930 24.790  -2.773  1.00 25.25 ? 109 ARG A CZ  1 
ATOM   848  N NH1 . ARG A 1 107 ? -33.604 24.032  -3.810  1.00 27.00 ? 109 ARG A NH1 1 
ATOM   849  N NH2 . ARG A 1 107 ? -33.075 25.721  -2.358  1.00 28.47 ? 109 ARG A NH2 1 
ATOM   850  N N   . ALA A 1 108 ? -37.572 25.370  -6.967  1.00 15.96 ? 110 ALA A N   1 
ATOM   851  C CA  . ALA A 1 108 ? -36.780 25.575  -8.164  1.00 14.64 ? 110 ALA A CA  1 
ATOM   852  C C   . ALA A 1 108 ? -35.645 26.535  -7.868  1.00 17.67 ? 110 ALA A C   1 
ATOM   853  O O   . ALA A 1 108 ? -35.766 27.428  -7.028  1.00 17.27 ? 110 ALA A O   1 
ATOM   854  C CB  . ALA A 1 108 ? -37.626 26.130  -9.317  1.00 13.15 ? 110 ALA A CB  1 
ATOM   855  N N   . GLU A 1 109 ? -34.540 26.347  -8.581  1.00 15.67 ? 111 GLU A N   1 
ATOM   856  C CA  . GLU A 1 109 ? -33.441 27.297  -8.592  1.00 14.86 ? 111 GLU A CA  1 
ATOM   857  C C   . GLU A 1 109 ? -33.300 27.798  -10.018 1.00 15.69 ? 111 GLU A C   1 
ATOM   858  O O   . GLU A 1 109 ? -33.242 26.998  -10.957 1.00 14.25 ? 111 GLU A O   1 
ATOM   859  C CB  . GLU A 1 109 ? -32.136 26.650  -8.104  1.00 16.93 ? 111 GLU A CB  1 
ATOM   860  C CG  . GLU A 1 109 ? -32.215 26.298  -6.612  1.00 20.98 ? 111 GLU A CG  1 
ATOM   861  C CD  . GLU A 1 109 ? -30.897 25.798  -6.021  1.00 25.91 ? 111 GLU A CD  1 
ATOM   862  O OE1 . GLU A 1 109 ? -29.861 25.793  -6.719  1.00 26.90 ? 111 GLU A OE1 1 
ATOM   863  O OE2 . GLU A 1 109 ? -30.920 25.362  -4.855  1.00 27.80 ? 111 GLU A OE2 1 
ATOM   864  N N   . VAL A 1 110 ? -33.276 29.113  -10.176 1.00 13.89 ? 112 VAL A N   1 
ATOM   865  C CA  . VAL A 1 110 ? -33.146 29.757  -11.473 1.00 13.51 ? 112 VAL A CA  1 
ATOM   866  C C   . VAL A 1 110 ? -31.821 30.493  -11.446 1.00 15.91 ? 112 VAL A C   1 
ATOM   867  O O   . VAL A 1 110 ? -31.605 31.350  -10.579 1.00 15.81 ? 112 VAL A O   1 
ATOM   868  C CB  . VAL A 1 110 ? -34.311 30.723  -11.745 1.00 14.57 ? 112 VAL A CB  1 
ATOM   869  C CG1 . VAL A 1 110 ? -34.190 31.341  -13.139 1.00 12.98 ? 112 VAL A CG1 1 
ATOM   870  C CG2 . VAL A 1 110 ? -35.659 30.030  -11.537 1.00 13.01 ? 112 VAL A CG2 1 
ATOM   871  N N   . LYS A 1 111 ? -30.919 30.151  -12.362 1.00 14.37 ? 113 LYS A N   1 
ATOM   872  C CA  . LYS A 1 111 ? -29.595 30.757  -12.331 1.00 14.80 ? 113 LYS A CA  1 
ATOM   873  C C   . LYS A 1 111 ? -28.908 30.578  -13.674 1.00 15.19 ? 113 LYS A C   1 
ATOM   874  O O   . LYS A 1 111 ? -29.350 29.809  -14.533 1.00 16.70 ? 113 LYS A O   1 
ATOM   875  C CB  . LYS A 1 111 ? -28.722 30.164  -11.228 1.00 17.52 ? 113 LYS A CB  1 
ATOM   876  C CG  . LYS A 1 111 ? -28.314 28.715  -11.483 1.00 16.57 ? 113 LYS A CG  1 
ATOM   877  C CD  . LYS A 1 111 ? -27.797 28.102  -10.204 1.00 22.80 ? 113 LYS A CD  1 
ATOM   878  C CE  . LYS A 1 111 ? -28.728 27.038  -9.690  1.00 27.10 ? 113 LYS A CE  1 
ATOM   879  N NZ  . LYS A 1 111 ? -28.073 26.212  -8.646  1.00 30.37 ? 113 LYS A NZ  1 
ATOM   880  N N   . PHE A 1 112 ? -27.806 31.296  -13.840 1.00 14.83 ? 114 PHE A N   1 
ATOM   881  C CA  . PHE A 1 112 ? -27.015 31.132  -15.047 1.00 14.95 ? 114 PHE A CA  1 
ATOM   882  C C   . PHE A 1 112 ? -26.052 29.969  -14.875 1.00 17.34 ? 114 PHE A C   1 
ATOM   883  O O   . PHE A 1 112 ? -25.477 29.758  -13.799 1.00 15.51 ? 114 PHE A O   1 
ATOM   884  C CB  . PHE A 1 112 ? -26.262 32.415  -15.379 1.00 17.08 ? 114 PHE A CB  1 
ATOM   885  C CG  . PHE A 1 112 ? -27.037 33.340  -16.266 1.00 17.19 ? 114 PHE A CG  1 
ATOM   886  C CD1 . PHE A 1 112 ? -26.989 33.211  -17.637 1.00 17.17 ? 114 PHE A CD1 1 
ATOM   887  C CD2 . PHE A 1 112 ? -27.862 34.306  -15.717 1.00 16.02 ? 114 PHE A CD2 1 
ATOM   888  C CE1 . PHE A 1 112 ? -27.719 34.054  -18.448 1.00 18.10 ? 114 PHE A CE1 1 
ATOM   889  C CE2 . PHE A 1 112 ? -28.599 35.150  -16.515 1.00 15.02 ? 114 PHE A CE2 1 
ATOM   890  C CZ  . PHE A 1 112 ? -28.528 35.031  -17.882 1.00 18.90 ? 114 PHE A CZ  1 
ATOM   891  N N   . GLU A 1 113 ? -25.916 29.187  -15.937 1.00 15.40 ? 115 GLU A N   1 
ATOM   892  C CA  . GLU A 1 113 ? -24.890 28.161  -16.026 1.00 18.90 ? 115 GLU A CA  1 
ATOM   893  C C   . GLU A 1 113 ? -24.193 28.440  -17.349 1.00 21.41 ? 115 GLU A C   1 
ATOM   894  O O   . GLU A 1 113 ? -24.798 28.281  -18.410 1.00 17.92 ? 115 GLU A O   1 
ATOM   895  C CB  . GLU A 1 113 ? -25.505 26.766  -15.973 1.00 15.19 ? 115 GLU A CB  1 
ATOM   896  C CG  . GLU A 1 113 ? -25.975 26.413  -14.559 1.00 16.71 ? 115 GLU A CG  1 
ATOM   897  C CD  . GLU A 1 113 ? -26.693 25.094  -14.451 1.00 22.19 ? 115 GLU A CD  1 
ATOM   898  O OE1 . GLU A 1 113 ? -26.536 24.234  -15.343 1.00 21.62 ? 115 GLU A OE1 1 
ATOM   899  O OE2 . GLU A 1 113 ? -27.361 24.874  -13.423 1.00 22.38 ? 115 GLU A OE2 1 
ATOM   900  N N   . GLY A 1 114 ? -22.960 28.935  -17.290 1.00 24.10 ? 116 GLY A N   1 
ATOM   901  C CA  . GLY A 1 114 ? -22.378 29.505  -18.497 1.00 23.81 ? 116 GLY A CA  1 
ATOM   902  C C   . GLY A 1 114 ? -23.206 30.692  -18.960 1.00 24.38 ? 116 GLY A C   1 
ATOM   903  O O   . GLY A 1 114 ? -23.527 31.593  -18.180 1.00 27.40 ? 116 GLY A O   1 
ATOM   904  N N   . ASP A 1 115 ? -23.585 30.700  -20.237 1.00 23.86 ? 117 ASP A N   1 
ATOM   905  C CA  . ASP A 1 115 ? -24.459 31.739  -20.772 1.00 22.50 ? 117 ASP A CA  1 
ATOM   906  C C   . ASP A 1 115 ? -25.912 31.296  -20.863 1.00 20.28 ? 117 ASP A C   1 
ATOM   907  O O   . ASP A 1 115 ? -26.731 32.001  -21.468 1.00 17.32 ? 117 ASP A O   1 
ATOM   908  C CB  . ASP A 1 115 ? -23.968 32.197  -22.145 1.00 25.82 ? 117 ASP A CB  1 
ATOM   909  C CG  . ASP A 1 115 ? -22.645 32.937  -22.066 1.00 31.00 ? 117 ASP A CG  1 
ATOM   910  O OD1 . ASP A 1 115 ? -22.419 33.646  -21.055 1.00 29.70 ? 117 ASP A OD1 1 
ATOM   911  O OD2 . ASP A 1 115 ? -21.839 32.808  -23.010 1.00 34.04 ? 117 ASP A OD2 1 
ATOM   912  N N   . THR A 1 116 ? -26.251 30.169  -20.254 1.00 17.64 ? 118 THR A N   1 
ATOM   913  C CA  . THR A 1 116 ? -27.593 29.603  -20.298 1.00 16.90 ? 118 THR A CA  1 
ATOM   914  C C   . THR A 1 116 ? -28.322 29.893  -18.989 1.00 17.60 ? 118 THR A C   1 
ATOM   915  O O   . THR A 1 116 ? -27.772 29.681  -17.899 1.00 16.45 ? 118 THR A O   1 
ATOM   916  C CB  . THR A 1 116 ? -27.516 28.092  -20.542 1.00 14.76 ? 118 THR A CB  1 
ATOM   917  O OG1 . THR A 1 116 ? -26.854 27.854  -21.795 1.00 17.85 ? 118 THR A OG1 1 
ATOM   918  C CG2 . THR A 1 116 ? -28.906 27.454  -20.578 1.00 11.80 ? 118 THR A CG2 1 
ATOM   919  N N   . LEU A 1 117 ? -29.544 30.402  -19.104 1.00 16.01 ? 119 LEU A N   1 
ATOM   920  C CA  . LEU A 1 117 ? -30.428 30.557  -17.956 1.00 15.31 ? 119 LEU A CA  1 
ATOM   921  C C   . LEU A 1 117 ? -31.104 29.215  -17.707 1.00 16.19 ? 119 LEU A C   1 
ATOM   922  O O   . LEU A 1 117 ? -31.797 28.697  -18.594 1.00 14.60 ? 119 LEU A O   1 
ATOM   923  C CB  . LEU A 1 117 ? -31.452 31.661  -18.235 1.00 15.61 ? 119 LEU A CB  1 
ATOM   924  C CG  . LEU A 1 117 ? -32.289 32.189  -17.063 1.00 14.86 ? 119 LEU A CG  1 
ATOM   925  C CD1 . LEU A 1 117 ? -33.467 31.251  -16.753 1.00 13.15 ? 119 LEU A CD1 1 
ATOM   926  C CD2 . LEU A 1 117 ? -31.429 32.407  -15.806 1.00 14.93 ? 119 LEU A CD2 1 
ATOM   927  N N   . VAL A 1 118 ? -30.875 28.629  -16.526 1.00 13.42 ? 120 VAL A N   1 
ATOM   928  C CA  . VAL A 1 118 ? -31.380 27.304  -16.186 1.00 11.63 ? 120 VAL A CA  1 
ATOM   929  C C   . VAL A 1 118 ? -32.429 27.429  -15.089 1.00 13.96 ? 120 VAL A C   1 
ATOM   930  O O   . VAL A 1 118 ? -32.192 28.082  -14.067 1.00 14.32 ? 120 VAL A O   1 
ATOM   931  C CB  . VAL A 1 118 ? -30.244 26.370  -15.739 1.00 13.98 ? 120 VAL A CB  1 
ATOM   932  C CG1 . VAL A 1 118 ? -30.772 24.969  -15.508 1.00 12.66 ? 120 VAL A CG1 1 
ATOM   933  C CG2 . VAL A 1 118 ? -29.151 26.354  -16.807 1.00 12.38 ? 120 VAL A CG2 1 
ATOM   934  N N   . ASN A 1 119 ? -33.576 26.782  -15.296 1.00 12.48 ? 121 ASN A N   1 
ATOM   935  C CA  . ASN A 1 119 ? -34.628 26.639  -14.292 1.00 11.77 ? 121 ASN A CA  1 
ATOM   936  C C   . ASN A 1 119 ? -34.720 25.158  -13.950 1.00 15.14 ? 121 ASN A C   1 
ATOM   937  O O   . ASN A 1 119 ? -35.222 24.368  -14.756 1.00 15.84 ? 121 ASN A O   1 
ATOM   938  C CB  . ASN A 1 119 ? -35.966 27.163  -14.828 1.00 13.33 ? 121 ASN A CB  1 
ATOM   939  C CG  . ASN A 1 119 ? -37.110 26.994  -13.836 1.00 18.71 ? 121 ASN A CG  1 
ATOM   940  O OD1 . ASN A 1 119 ? -36.877 26.879  -12.638 1.00 13.71 ? 121 ASN A OD1 1 
ATOM   941  N ND2 . ASN A 1 119 ? -38.357 26.935  -14.340 1.00 12.60 ? 121 ASN A ND2 1 
ATOM   942  N N   . ARG A 1 120 ? -34.232 24.776  -12.768 1.00 14.85 ? 122 ARG A N   1 
ATOM   943  C CA  . ARG A 1 120 ? -34.223 23.385  -12.318 1.00 14.75 ? 122 ARG A CA  1 
ATOM   944  C C   . ARG A 1 120 ? -35.209 23.221  -11.173 1.00 15.94 ? 122 ARG A C   1 
ATOM   945  O O   . ARG A 1 120 ? -35.123 23.943  -10.170 1.00 13.59 ? 122 ARG A O   1 
ATOM   946  C CB  . ARG A 1 120 ? -32.828 22.955  -11.851 1.00 16.82 ? 122 ARG A CB  1 
ATOM   947  C CG  . ARG A 1 120 ? -32.683 21.441  -11.702 1.00 19.86 ? 122 ARG A CG  1 
ATOM   948  C CD  . ARG A 1 120 ? -31.253 21.047  -11.367 1.00 22.24 ? 122 ARG A CD  1 
ATOM   949  N NE  . ARG A 1 120 ? -30.364 21.319  -12.489 1.00 23.40 ? 122 ARG A NE  1 
ATOM   950  C CZ  . ARG A 1 120 ? -30.250 20.567  -13.575 1.00 20.31 ? 122 ARG A CZ  1 
ATOM   951  N NH1 . ARG A 1 120 ? -30.901 19.414  -13.702 1.00 17.42 ? 122 ARG A NH1 1 
ATOM   952  N NH2 . ARG A 1 120 ? -29.452 20.976  -14.556 1.00 21.10 ? 122 ARG A NH2 1 
ATOM   953  N N   . ILE A 1 121 ? -36.111 22.247  -11.308 1.00 13.65 ? 123 ILE A N   1 
ATOM   954  C CA  . ILE A 1 121 ? -37.312 22.151  -10.483 1.00 14.91 ? 123 ILE A CA  1 
ATOM   955  C C   . ILE A 1 121 ? -37.456 20.761  -9.886  1.00 14.80 ? 123 ILE A C   1 
ATOM   956  O O   . ILE A 1 121 ? -37.298 19.749  -10.582 1.00 15.06 ? 123 ILE A O   1 
ATOM   957  C CB  . ILE A 1 121 ? -38.582 22.453  -11.300 1.00 13.60 ? 123 ILE A CB  1 
ATOM   958  C CG1 . ILE A 1 121 ? -38.507 23.826  -11.958 1.00 12.23 ? 123 ILE A CG1 1 
ATOM   959  C CG2 . ILE A 1 121 ? -39.843 22.286  -10.425 1.00 13.93 ? 123 ILE A CG2 1 
ATOM   960  C CD1 . ILE A 1 121 ? -39.040 23.757  -13.401 1.00 15.58 ? 123 ILE A CD1 1 
ATOM   961  N N   . GLU A 1 122 ? -37.872 20.726  -8.622  1.00 14.88 ? 124 GLU A N   1 
ATOM   962  C CA  . GLU A 1 122 ? -38.360 19.511  -7.977  1.00 17.21 ? 124 GLU A CA  1 
ATOM   963  C C   . GLU A 1 122 ? -39.839 19.695  -7.613  1.00 16.55 ? 124 GLU A C   1 
ATOM   964  O O   . GLU A 1 122 ? -40.199 20.649  -6.924  1.00 15.32 ? 124 GLU A O   1 
ATOM   965  C CB  . GLU A 1 122 ? -37.540 19.198  -6.725  1.00 20.15 ? 124 GLU A CB  1 
ATOM   966  C CG  . GLU A 1 122 ? -36.038 19.326  -6.918  1.00 23.87 ? 124 GLU A CG  1 
ATOM   967  C CD  . GLU A 1 122 ? -35.255 18.913  -5.688  1.00 35.64 ? 124 GLU A CD  1 
ATOM   968  O OE1 . GLU A 1 122 ? -35.798 18.143  -4.867  1.00 40.91 ? 124 GLU A OE1 1 
ATOM   969  O OE2 . GLU A 1 122 ? -34.098 19.358  -5.541  1.00 41.58 ? 124 GLU A OE2 1 
ATOM   970  N N   . LEU A 1 123 ? -40.692 18.786  -8.084  1.00 14.99 ? 125 LEU A N   1 
ATOM   971  C CA  . LEU A 1 123 ? -42.134 18.899  -7.896  1.00 15.93 ? 125 LEU A CA  1 
ATOM   972  C C   . LEU A 1 123 ? -42.644 17.659  -7.182  1.00 15.91 ? 125 LEU A C   1 
ATOM   973  O O   . LEU A 1 123 ? -42.432 16.536  -7.653  1.00 18.62 ? 125 LEU A O   1 
ATOM   974  C CB  . LEU A 1 123 ? -42.870 19.068  -9.237  1.00 14.63 ? 125 LEU A CB  1 
ATOM   975  C CG  . LEU A 1 123 ? -44.396 19.274  -9.221  1.00 13.98 ? 125 LEU A CG  1 
ATOM   976  C CD1 . LEU A 1 123 ? -44.850 20.206  -10.380 1.00 14.59 ? 125 LEU A CD1 1 
ATOM   977  C CD2 . LEU A 1 123 ? -45.183 17.959  -9.230  1.00 15.04 ? 125 LEU A CD2 1 
ATOM   978  N N   . LYS A 1 124 ? -43.347 17.863  -6.069  1.00 16.27 ? 126 LYS A N   1 
ATOM   979  C CA  . LYS A 1 124 ? -44.019 16.792  -5.349  1.00 17.82 ? 126 LYS A CA  1 
ATOM   980  C C   . LYS A 1 124 ? -45.505 17.104  -5.302  1.00 17.69 ? 126 LYS A C   1 
ATOM   981  O O   . LYS A 1 124 ? -45.903 18.190  -4.854  1.00 20.39 ? 126 LYS A O   1 
ATOM   982  C CB  . LYS A 1 124 ? -43.464 16.643  -3.926  1.00 20.48 ? 126 LYS A CB  1 
ATOM   983  C CG  . LYS A 1 124 ? -44.143 15.551  -3.086  1.00 24.98 ? 126 LYS A CG  1 
ATOM   984  C CD  . LYS A 1 124 ? -43.293 14.270  -3.026  1.00 35.74 ? 126 LYS A CD  1 
ATOM   985  C CE  . LYS A 1 124 ? -44.107 13.020  -2.650  1.00 33.67 ? 126 LYS A CE  1 
ATOM   986  N NZ  . LYS A 1 124 ? -45.110 12.629  -3.703  1.00 32.29 ? 126 LYS A NZ  1 
ATOM   987  N N   . GLY A 1 125 ? -46.319 16.173  -5.767  1.00 19.53 ? 127 GLY A N   1 
ATOM   988  C CA  . GLY A 1 125 ? -47.767 16.305  -5.691  1.00 18.36 ? 127 GLY A CA  1 
ATOM   989  C C   . GLY A 1 125 ? -48.355 15.168  -4.877  1.00 22.52 ? 127 GLY A C   1 
ATOM   990  O O   . GLY A 1 125 ? -47.968 14.011  -5.049  1.00 20.39 ? 127 GLY A O   1 
ATOM   991  N N   . ILE A 1 126 ? -49.310 15.503  -4.003  1.00 22.92 ? 128 ILE A N   1 
ATOM   992  C CA  . ILE A 1 126 ? -49.946 14.532  -3.119  1.00 25.09 ? 128 ILE A CA  1 
ATOM   993  C C   . ILE A 1 126 ? -51.446 14.789  -3.107  1.00 26.43 ? 128 ILE A C   1 
ATOM   994  O O   . ILE A 1 126 ? -51.927 15.839  -3.545  1.00 22.66 ? 128 ILE A O   1 
ATOM   995  C CB  . ILE A 1 126 ? -49.413 14.604  -1.671  1.00 28.20 ? 128 ILE A CB  1 
ATOM   996  C CG1 . ILE A 1 126 ? -49.623 16.011  -1.107  1.00 25.12 ? 128 ILE A CG1 1 
ATOM   997  C CG2 . ILE A 1 126 ? -47.950 14.227  -1.631  1.00 31.41 ? 128 ILE A CG2 1 
ATOM   998  C CD1 . ILE A 1 126 ? -48.866 16.317  0.191   1.00 32.24 ? 128 ILE A CD1 1 
ATOM   999  N N   . ASP A 1 127 ? -52.186 13.806  -2.595  1.00 26.58 ? 129 ASP A N   1 
ATOM   1000 C CA  . ASP A 1 127 ? -53.614 13.935  -2.317  1.00 28.52 ? 129 ASP A CA  1 
ATOM   1001 C C   . ASP A 1 127 ? -54.465 14.030  -3.570  1.00 25.77 ? 129 ASP A C   1 
ATOM   1002 O O   . ASP A 1 127 ? -55.587 14.540  -3.512  1.00 25.71 ? 129 ASP A O   1 
ATOM   1003 C CB  . ASP A 1 127 ? -53.895 15.152  -1.433  1.00 25.70 ? 129 ASP A CB  1 
ATOM   1004 C CG  . ASP A 1 127 ? -54.111 14.783  -0.006  1.00 36.41 ? 129 ASP A CG  1 
ATOM   1005 O OD1 . ASP A 1 127 ? -53.420 13.852  0.462   1.00 37.89 ? 129 ASP A OD1 1 
ATOM   1006 O OD2 . ASP A 1 127 ? -54.982 15.408  0.635   1.00 43.04 ? 129 ASP A OD2 1 
ATOM   1007 N N   . PHE A 1 128 ? -53.978 13.559  -4.710  1.00 19.76 ? 130 PHE A N   1 
ATOM   1008 C CA  . PHE A 1 128 ? -54.754 13.674  -5.931  1.00 22.82 ? 130 PHE A CA  1 
ATOM   1009 C C   . PHE A 1 128 ? -55.693 12.487  -6.085  1.00 24.14 ? 130 PHE A C   1 
ATOM   1010 O O   . PHE A 1 128 ? -55.447 11.399  -5.564  1.00 25.32 ? 130 PHE A O   1 
ATOM   1011 C CB  . PHE A 1 128 ? -53.837 13.788  -7.146  1.00 20.93 ? 130 PHE A CB  1 
ATOM   1012 C CG  . PHE A 1 128 ? -53.269 15.153  -7.325  1.00 20.58 ? 130 PHE A CG  1 
ATOM   1013 C CD1 . PHE A 1 128 ? -53.944 16.109  -8.063  1.00 17.74 ? 130 PHE A CD1 1 
ATOM   1014 C CD2 . PHE A 1 128 ? -52.071 15.493  -6.721  1.00 20.50 ? 130 PHE A CD2 1 
ATOM   1015 C CE1 . PHE A 1 128 ? -53.423 17.380  -8.210  1.00 20.48 ? 130 PHE A CE1 1 
ATOM   1016 C CE2 . PHE A 1 128 ? -51.540 16.767  -6.866  1.00 19.82 ? 130 PHE A CE2 1 
ATOM   1017 C CZ  . PHE A 1 128 ? -52.223 17.710  -7.609  1.00 17.38 ? 130 PHE A CZ  1 
ATOM   1018 N N   . LYS A 1 129 ? -56.787 12.721  -6.792  1.00 24.41 ? 131 LYS A N   1 
ATOM   1019 C CA  . LYS A 1 129 ? -57.766 11.690  -7.081  1.00 26.47 ? 131 LYS A CA  1 
ATOM   1020 C C   . LYS A 1 129 ? -57.384 11.028  -8.399  1.00 28.37 ? 131 LYS A C   1 
ATOM   1021 O O   . LYS A 1 129 ? -57.141 11.721  -9.390  1.00 26.11 ? 131 LYS A O   1 
ATOM   1022 C CB  . LYS A 1 129 ? -59.160 12.318  -7.154  1.00 28.25 ? 131 LYS A CB  1 
ATOM   1023 C CG  . LYS A 1 129 ? -59.584 12.992  -5.835  1.00 27.35 ? 131 LYS A CG  1 
ATOM   1024 C CD  . LYS A 1 129 ? -60.855 13.812  -6.000  1.00 28.57 ? 131 LYS A CD  1 
ATOM   1025 C CE  . LYS A 1 129 ? -61.296 14.424  -4.674  1.00 29.31 ? 131 LYS A CE  1 
ATOM   1026 N N   . GLU A 1 130 ? -57.304 9.690   -8.406  1.00 28.57 ? 132 GLU A N   1 
ATOM   1027 C CA  . GLU A 1 130 ? -56.886 8.980   -9.616  1.00 30.34 ? 132 GLU A CA  1 
ATOM   1028 C C   . GLU A 1 130 ? -57.813 9.247   -10.797 1.00 34.68 ? 132 GLU A C   1 
ATOM   1029 O O   . GLU A 1 130 ? -57.356 9.249   -11.944 1.00 36.94 ? 132 GLU A O   1 
ATOM   1030 C CB  . GLU A 1 130 ? -56.784 7.479   -9.334  1.00 33.89 ? 132 GLU A CB  1 
ATOM   1031 C CG  . GLU A 1 130 ? -55.493 7.072   -8.632  1.00 36.49 ? 132 GLU A CG  1 
ATOM   1032 C CD  . GLU A 1 130 ? -54.238 7.430   -9.417  1.00 40.45 ? 132 GLU A CD  1 
ATOM   1033 O OE1 . GLU A 1 130 ? -54.314 7.535   -10.672 1.00 37.71 ? 132 GLU A OE1 1 
ATOM   1034 O OE2 . GLU A 1 130 ? -53.184 7.636   -8.765  1.00 32.04 ? 132 GLU A OE2 1 
ATOM   1035 N N   . ASP A 1 131 ? -59.107 9.463   -10.551 1.00 30.00 ? 133 ASP A N   1 
ATOM   1036 C CA  . ASP A 1 131 ? -60.053 9.847   -11.594 1.00 32.13 ? 133 ASP A CA  1 
ATOM   1037 C C   . ASP A 1 131 ? -60.483 11.306  -11.470 1.00 33.91 ? 133 ASP A C   1 
ATOM   1038 O O   . ASP A 1 131 ? -61.595 11.664  -11.861 1.00 36.11 ? 133 ASP A O   1 
ATOM   1039 C CB  . ASP A 1 131 ? -61.285 8.942   -11.590 1.00 38.57 ? 133 ASP A CB  1 
ATOM   1040 C CG  . ASP A 1 131 ? -61.951 8.855   -12.964 1.00 46.78 ? 133 ASP A CG  1 
ATOM   1041 O OD1 . ASP A 1 131 ? -63.205 8.812   -13.029 1.00 49.79 ? 133 ASP A OD1 1 
ATOM   1042 O OD2 . ASP A 1 131 ? -61.221 8.864   -13.981 1.00 48.42 ? 133 ASP A OD2 1 
ATOM   1043 N N   . GLY A 1 132 ? -59.621 12.150  -10.908 1.00 28.74 ? 134 GLY A N   1 
ATOM   1044 C CA  . GLY A 1 132 ? -59.864 13.573  -10.884 1.00 28.35 ? 134 GLY A CA  1 
ATOM   1045 C C   . GLY A 1 132 ? -59.475 14.232  -12.194 1.00 25.77 ? 134 GLY A C   1 
ATOM   1046 O O   . GLY A 1 132 ? -59.008 13.600  -13.140 1.00 23.71 ? 134 GLY A O   1 
ATOM   1047 N N   . ASN A 1 133 ? -59.664 15.551  -12.236 1.00 24.44 ? 135 ASN A N   1 
ATOM   1048 C CA  . ASN A 1 133 ? -59.351 16.304  -13.443 1.00 24.73 ? 135 ASN A CA  1 
ATOM   1049 C C   . ASN A 1 133 ? -57.870 16.278  -13.798 1.00 22.50 ? 135 ASN A C   1 
ATOM   1050 O O   . ASN A 1 133 ? -57.530 16.515  -14.962 1.00 22.37 ? 135 ASN A O   1 
ATOM   1051 C CB  . ASN A 1 133 ? -59.821 17.750  -13.283 1.00 21.45 ? 135 ASN A CB  1 
ATOM   1052 C CG  . ASN A 1 133 ? -61.327 17.858  -13.233 1.00 25.47 ? 135 ASN A CG  1 
ATOM   1053 O OD1 . ASN A 1 133 ? -62.027 17.035  -13.813 1.00 27.46 ? 135 ASN A OD1 1 
ATOM   1054 N ND2 . ASN A 1 133 ? -61.832 18.843  -12.503 1.00 24.62 ? 135 ASN A ND2 1 
ATOM   1055 N N   . ILE A 1 134 ? -56.988 15.986  -12.841 1.00 22.32 ? 136 ILE A N   1 
ATOM   1056 C CA  . ILE A 1 134 ? -55.556 16.124  -13.068 1.00 20.03 ? 136 ILE A CA  1 
ATOM   1057 C C   . ILE A 1 134 ? -55.007 14.763  -13.476 1.00 22.23 ? 136 ILE A C   1 
ATOM   1058 O O   . ILE A 1 134 ? -54.575 14.576  -14.617 1.00 22.17 ? 136 ILE A O   1 
ATOM   1059 C CB  . ILE A 1 134 ? -54.836 16.673  -11.823 1.00 19.20 ? 136 ILE A CB  1 
ATOM   1060 C CG1 . ILE A 1 134 ? -55.057 18.176  -11.702 1.00 21.64 ? 136 ILE A CG1 1 
ATOM   1061 C CG2 . ILE A 1 134 ? -53.338 16.452  -11.918 1.00 19.34 ? 136 ILE A CG2 1 
ATOM   1062 C CD1 . ILE A 1 134 ? -56.385 18.526  -11.101 1.00 21.10 ? 136 ILE A CD1 1 
ATOM   1063 N N   . LEU A 1 135 ? -55.049 13.794  -12.553 1.00 22.21 ? 137 LEU A N   1 
ATOM   1064 C CA  . LEU A 1 135 ? -54.559 12.450  -12.841 1.00 23.33 ? 137 LEU A CA  1 
ATOM   1065 C C   . LEU A 1 135 ? -55.391 11.759  -13.916 1.00 28.69 ? 137 LEU A C   1 
ATOM   1066 O O   . LEU A 1 135 ? -54.888 10.853  -14.594 1.00 26.31 ? 137 LEU A O   1 
ATOM   1067 C CB  . LEU A 1 135 ? -54.545 11.624  -11.551 1.00 26.23 ? 137 LEU A CB  1 
ATOM   1068 C CG  . LEU A 1 135 ? -53.357 11.925  -10.628 1.00 25.88 ? 137 LEU A CG  1 
ATOM   1069 C CD1 . LEU A 1 135 ? -53.275 10.956  -9.445  1.00 24.74 ? 137 LEU A CD1 1 
ATOM   1070 C CD2 . LEU A 1 135 ? -52.049 11.921  -11.409 1.00 24.12 ? 137 LEU A CD2 1 
ATOM   1071 N N   . GLY A 1 136 ? -56.639 12.178  -14.107 1.00 24.67 ? 138 GLY A N   1 
ATOM   1072 C CA  . GLY A 1 136 ? -57.466 11.622  -15.153 1.00 26.51 ? 138 GLY A CA  1 
ATOM   1073 C C   . GLY A 1 136 ? -57.421 12.361  -16.465 1.00 27.47 ? 138 GLY A C   1 
ATOM   1074 O O   . GLY A 1 136 ? -58.176 12.013  -17.377 1.00 25.73 ? 138 GLY A O   1 
ATOM   1075 N N   . HIS A 1 137 ? -56.575 13.386  -16.580 1.00 24.34 ? 139 HIS A N   1 
ATOM   1076 C CA  . HIS A 1 137 ? -56.368 14.136  -17.819 1.00 21.45 ? 139 HIS A CA  1 
ATOM   1077 C C   . HIS A 1 137 ? -57.691 14.652  -18.397 1.00 23.57 ? 139 HIS A C   1 
ATOM   1078 O O   . HIS A 1 137 ? -58.058 14.364  -19.536 1.00 23.01 ? 139 HIS A O   1 
ATOM   1079 C CB  . HIS A 1 137 ? -55.626 13.282  -18.854 1.00 27.06 ? 139 HIS A CB  1 
ATOM   1080 C CG  . HIS A 1 137 ? -54.219 12.940  -18.470 1.00 23.75 ? 139 HIS A CG  1 
ATOM   1081 N ND1 . HIS A 1 137 ? -53.891 11.783  -17.795 1.00 23.15 ? 139 HIS A ND1 1 
ATOM   1082 C CD2 . HIS A 1 137 ? -53.052 13.600  -18.672 1.00 21.40 ? 139 HIS A CD2 1 
ATOM   1083 C CE1 . HIS A 1 137 ? -52.585 11.743  -17.595 1.00 23.55 ? 139 HIS A CE1 1 
ATOM   1084 N NE2 . HIS A 1 137 ? -52.052 12.833  -18.118 1.00 23.07 ? 139 HIS A NE2 1 
ATOM   1085 N N   . LYS A 1 138 ? -58.403 15.452  -17.602 1.00 23.82 ? 140 LYS A N   1 
ATOM   1086 C CA  . LYS A 1 138 ? -59.692 15.973  -18.038 1.00 27.00 ? 140 LYS A CA  1 
ATOM   1087 C C   . LYS A 1 138 ? -59.657 17.472  -18.324 1.00 26.09 ? 140 LYS A C   1 
ATOM   1088 O O   . LYS A 1 138 ? -60.713 18.102  -18.447 1.00 26.42 ? 140 LYS A O   1 
ATOM   1089 C CB  . LYS A 1 138 ? -60.774 15.642  -17.010 1.00 26.79 ? 140 LYS A CB  1 
ATOM   1090 C CG  . LYS A 1 138 ? -60.922 14.149  -16.727 1.00 29.80 ? 140 LYS A CG  1 
ATOM   1091 C CD  . LYS A 1 138 ? -61.910 13.891  -15.588 1.00 30.95 ? 140 LYS A CD  1 
ATOM   1092 C CE  . LYS A 1 138 ? -61.936 12.418  -15.204 1.00 31.03 ? 140 LYS A CE  1 
ATOM   1093 N NZ  . LYS A 1 138 ? -62.895 12.158  -14.088 1.00 35.95 ? 140 LYS A NZ  1 
ATOM   1094 N N   . LEU A 1 139 ? -58.466 18.046  -18.476 1.00 21.69 ? 141 LEU A N   1 
ATOM   1095 C CA  . LEU A 1 139 ? -58.290 19.472  -18.712 1.00 22.19 ? 141 LEU A CA  1 
ATOM   1096 C C   . LEU A 1 139 ? -57.986 19.763  -20.176 1.00 27.20 ? 141 LEU A C   1 
ATOM   1097 O O   . LEU A 1 139 ? -57.187 19.066  -20.809 1.00 25.94 ? 141 LEU A O   1 
ATOM   1098 C CB  . LEU A 1 139 ? -57.164 20.019  -17.834 1.00 23.67 ? 141 LEU A CB  1 
ATOM   1099 C CG  . LEU A 1 139 ? -57.366 19.851  -16.327 1.00 22.42 ? 141 LEU A CG  1 
ATOM   1100 C CD1 . LEU A 1 139 ? -56.248 20.541  -15.585 1.00 20.87 ? 141 LEU A CD1 1 
ATOM   1101 C CD2 . LEU A 1 139 ? -58.711 20.459  -15.921 1.00 19.16 ? 141 LEU A CD2 1 
ATOM   1102 N N   . GLU A 1 140 ? -58.613 20.815  -20.697 1.00 24.02 ? 142 GLU A N   1 
ATOM   1103 C CA  . GLU A 1 140 ? -58.386 21.235  -22.071 1.00 26.40 ? 142 GLU A CA  1 
ATOM   1104 C C   . GLU A 1 140 ? -56.938 21.676  -22.252 1.00 23.11 ? 142 GLU A C   1 
ATOM   1105 O O   . GLU A 1 140 ? -56.302 22.195  -21.330 1.00 20.83 ? 142 GLU A O   1 
ATOM   1106 C CB  . GLU A 1 140 ? -59.329 22.386  -22.437 1.00 24.48 ? 142 GLU A CB  1 
ATOM   1107 C CG  . GLU A 1 140 ? -60.795 22.006  -22.499 1.00 30.28 ? 142 GLU A CG  1 
ATOM   1108 C CD  . GLU A 1 140 ? -61.708 23.191  -22.834 1.00 34.64 ? 142 GLU A CD  1 
ATOM   1109 O OE1 . GLU A 1 140 ? -62.942 22.989  -22.873 1.00 39.03 ? 142 GLU A OE1 1 
ATOM   1110 O OE2 . GLU A 1 140 ? -61.199 24.315  -23.073 1.00 31.85 ? 142 GLU A OE2 1 
ATOM   1111 N N   . TYR A 1 141 ? -56.422 21.477  -23.464 1.00 23.12 ? 143 TYR A N   1 
ATOM   1112 C CA  . TYR A 1 141 ? -55.063 21.896  -23.816 1.00 20.49 ? 143 TYR A CA  1 
ATOM   1113 C C   . TYR A 1 141 ? -55.105 23.339  -24.325 1.00 23.18 ? 143 TYR A C   1 
ATOM   1114 O O   . TYR A 1 141 ? -55.020 23.623  -25.525 1.00 21.72 ? 143 TYR A O   1 
ATOM   1115 C CB  . TYR A 1 141 ? -54.462 20.948  -24.852 1.00 20.32 ? 143 TYR A CB  1 
ATOM   1116 C CG  . TYR A 1 141 ? -52.993 21.201  -25.157 1.00 18.40 ? 143 TYR A CG  1 
ATOM   1117 C CD1 . TYR A 1 141 ? -52.008 20.863  -24.235 1.00 17.72 ? 143 TYR A CD1 1 
ATOM   1118 C CD2 . TYR A 1 141 ? -52.596 21.802  -26.340 1.00 19.82 ? 143 TYR A CD2 1 
ATOM   1119 C CE1 . TYR A 1 141 ? -50.653 21.097  -24.496 1.00 16.54 ? 143 TYR A CE1 1 
ATOM   1120 C CE2 . TYR A 1 141 ? -51.255 22.045  -26.614 1.00 16.37 ? 143 TYR A CE2 1 
ATOM   1121 C CZ  . TYR A 1 141 ? -50.286 21.693  -25.683 1.00 15.03 ? 143 TYR A CZ  1 
ATOM   1122 O OH  . TYR A 1 141 ? -48.949 21.933  -25.955 1.00 14.53 ? 143 TYR A OH  1 
ATOM   1123 N N   . ASN A 1 142 ? -55.276 24.258  -23.377 1.00 21.89 ? 144 ASN A N   1 
ATOM   1124 C CA  . ASN A 1 142 ? -55.202 25.699  -23.623 1.00 21.28 ? 144 ASN A CA  1 
ATOM   1125 C C   . ASN A 1 142 ? -54.795 26.357  -22.310 1.00 22.10 ? 144 ASN A C   1 
ATOM   1126 O O   . ASN A 1 142 ? -54.436 25.672  -21.346 1.00 18.86 ? 144 ASN A O   1 
ATOM   1127 C CB  . ASN A 1 142 ? -56.529 26.262  -24.165 1.00 25.04 ? 144 ASN A CB  1 
ATOM   1128 C CG  . ASN A 1 142 ? -57.731 25.822  -23.350 1.00 26.77 ? 144 ASN A CG  1 
ATOM   1129 O OD1 . ASN A 1 142 ? -57.639 25.657  -22.137 1.00 26.65 ? 144 ASN A OD1 1 
ATOM   1130 N ND2 . ASN A 1 142 ? -58.873 25.657  -24.007 1.00 26.82 ? 144 ASN A ND2 1 
ATOM   1131 N N   . TYR A 1 143 ? -54.861 27.689  -22.256 1.00 19.46 ? 145 TYR A N   1 
ATOM   1132 C CA  . TYR A 1 143 ? -54.383 28.383  -21.069 1.00 21.97 ? 145 TYR A CA  1 
ATOM   1133 C C   . TYR A 1 143 ? -55.160 29.676  -20.839 1.00 20.94 ? 145 TYR A C   1 
ATOM   1134 O O   . TYR A 1 143 ? -55.471 30.405  -21.784 1.00 22.56 ? 145 TYR A O   1 
ATOM   1135 C CB  . TYR A 1 143 ? -52.876 28.674  -21.173 1.00 20.04 ? 145 TYR A CB  1 
ATOM   1136 C CG  . TYR A 1 143 ? -52.250 28.726  -19.812 1.00 16.19 ? 145 TYR A CG  1 
ATOM   1137 C CD1 . TYR A 1 143 ? -52.014 27.551  -19.102 1.00 19.33 ? 145 TYR A CD1 1 
ATOM   1138 C CD2 . TYR A 1 143 ? -51.941 29.936  -19.203 1.00 16.99 ? 145 TYR A CD2 1 
ATOM   1139 C CE1 . TYR A 1 143 ? -51.476 27.583  -17.824 1.00 16.70 ? 145 TYR A CE1 1 
ATOM   1140 C CE2 . TYR A 1 143 ? -51.385 29.975  -17.928 1.00 18.24 ? 145 TYR A CE2 1 
ATOM   1141 C CZ  . TYR A 1 143 ? -51.159 28.785  -17.249 1.00 16.17 ? 145 TYR A CZ  1 
ATOM   1142 O OH  . TYR A 1 143 ? -50.626 28.805  -15.981 1.00 15.82 ? 145 TYR A OH  1 
ATOM   1143 N N   . ASN A 1 144 ? -55.481 29.948  -19.573 1.00 19.60 ? 146 ASN A N   1 
ATOM   1144 C CA  . ASN A 1 144 ? -56.018 31.238  -19.140 1.00 18.02 ? 146 ASN A CA  1 
ATOM   1145 C C   . ASN A 1 144 ? -54.973 31.891  -18.253 1.00 19.09 ? 146 ASN A C   1 
ATOM   1146 O O   . ASN A 1 144 ? -54.795 31.480  -17.101 1.00 16.42 ? 146 ASN A O   1 
ATOM   1147 C CB  . ASN A 1 144 ? -57.329 31.083  -18.372 1.00 19.01 ? 146 ASN A CB  1 
ATOM   1148 C CG  . ASN A 1 144 ? -58.409 30.401  -19.180 1.00 23.47 ? 146 ASN A CG  1 
ATOM   1149 O OD1 . ASN A 1 144 ? -58.785 30.867  -20.252 1.00 26.34 ? 146 ASN A OD1 1 
ATOM   1150 N ND2 . ASN A 1 144 ? -58.915 29.292  -18.663 1.00 23.94 ? 146 ASN A ND2 1 
ATOM   1151 N N   . ASP A 1 145 ? -54.271 32.886  -18.786 1.00 14.39 ? 147 ASP A N   1 
ATOM   1152 C CA  . ASP A 1 145 ? -53.263 33.565  -17.994 1.00 15.12 ? 147 ASP A CA  1 
ATOM   1153 C C   . ASP A 1 145 ? -53.902 34.388  -16.883 1.00 20.24 ? 147 ASP A C   1 
ATOM   1154 O O   . ASP A 1 145 ? -55.100 34.688  -16.894 1.00 19.52 ? 147 ASP A O   1 
ATOM   1155 C CB  . ASP A 1 145 ? -52.410 34.480  -18.866 1.00 16.03 ? 147 ASP A CB  1 
ATOM   1156 C CG  . ASP A 1 145 ? -51.524 33.713  -19.814 1.00 18.92 ? 147 ASP A CG  1 
ATOM   1157 O OD1 . ASP A 1 145 ? -50.452 33.259  -19.370 1.00 17.33 ? 147 ASP A OD1 1 
ATOM   1158 O OD2 . ASP A 1 145 ? -51.889 33.588  -20.997 1.00 16.06 ? 147 ASP A OD2 1 
ATOM   1159 N N   . HIS A 1 146 ? -53.070 34.777  -15.922 1.00 18.25 ? 148 HIS A N   1 
ATOM   1160 C CA  . HIS A 1 146 ? -53.516 35.617  -14.823 1.00 19.66 ? 148 HIS A CA  1 
ATOM   1161 C C   . HIS A 1 146 ? -52.366 36.533  -14.452 1.00 20.19 ? 148 HIS A C   1 
ATOM   1162 O O   . HIS A 1 146 ? -51.202 36.114  -14.490 1.00 16.53 ? 148 HIS A O   1 
ATOM   1163 C CB  . HIS A 1 146 ? -53.945 34.779  -13.613 1.00 20.94 ? 148 HIS A CB  1 
ATOM   1164 C CG  . HIS A 1 146 ? -54.757 35.539  -12.604 1.00 24.98 ? 148 HIS A CG  1 
ATOM   1165 N ND1 . HIS A 1 146 ? -54.200 36.420  -11.701 1.00 23.95 ? 148 HIS A ND1 1 
ATOM   1166 C CD2 . HIS A 1 146 ? -56.084 35.510  -12.329 1.00 25.12 ? 148 HIS A CD2 1 
ATOM   1167 C CE1 . HIS A 1 146 ? -55.153 36.927  -10.937 1.00 23.39 ? 148 HIS A CE1 1 
ATOM   1168 N NE2 . HIS A 1 146 ? -56.305 36.393  -11.301 1.00 27.42 ? 148 HIS A NE2 1 
ATOM   1169 N N   . GLN A 1 147 ? -52.697 37.782  -14.114 1.00 19.41 ? 149 GLN A N   1 
ATOM   1170 C CA  . GLN A 1 147 ? -51.712 38.731  -13.597 1.00 18.18 ? 149 GLN A CA  1 
ATOM   1171 C C   . GLN A 1 147 ? -51.095 38.181  -12.318 1.00 18.92 ? 149 GLN A C   1 
ATOM   1172 O O   . GLN A 1 147 ? -51.718 37.413  -11.591 1.00 20.45 ? 149 GLN A O   1 
ATOM   1173 C CB  . GLN A 1 147 ? -52.368 40.059  -13.245 1.00 21.48 ? 149 GLN A CB  1 
ATOM   1174 C CG  . GLN A 1 147 ? -53.656 39.851  -12.463 1.00 26.91 ? 149 GLN A CG  1 
ATOM   1175 C CD  . GLN A 1 147 ? -54.649 40.980  -12.626 1.00 34.97 ? 149 GLN A CD  1 
ATOM   1176 O OE1 . GLN A 1 147 ? -54.278 42.112  -12.937 1.00 33.48 ? 149 GLN A OE1 1 
ATOM   1177 N NE2 . GLN A 1 147 ? -55.927 40.673  -12.418 1.00 39.84 ? 149 GLN A NE2 1 
ATOM   1178 N N   . VAL A 1 148 ? -49.874 38.609  -12.025 1.00 19.17 ? 150 VAL A N   1 
ATOM   1179 C CA  . VAL A 1 148 ? -49.180 38.216  -10.800 1.00 19.21 ? 150 VAL A CA  1 
ATOM   1180 C C   . VAL A 1 148 ? -48.755 39.483  -10.086 1.00 19.42 ? 150 VAL A C   1 
ATOM   1181 O O   . VAL A 1 148 ? -48.002 40.297  -10.640 1.00 18.78 ? 150 VAL A O   1 
ATOM   1182 C CB  . VAL A 1 148 ? -47.973 37.309  -11.083 1.00 16.74 ? 150 VAL A CB  1 
ATOM   1183 C CG1 . VAL A 1 148 ? -47.266 36.945  -9.765  1.00 16.21 ? 150 VAL A CG1 1 
ATOM   1184 C CG2 . VAL A 1 148 ? -48.434 36.029  -11.773 1.00 16.72 ? 150 VAL A CG2 1 
ATOM   1185 N N   . TYR A 1 149 ? -49.245 39.660  -8.865  1.00 21.06 ? 151 TYR A N   1 
ATOM   1186 C CA  . TYR A 1 149 ? -48.981 40.879  -8.112  1.00 22.52 ? 151 TYR A CA  1 
ATOM   1187 C C   . TYR A 1 149 ? -47.762 40.605  -7.233  1.00 18.38 ? 151 TYR A C   1 
ATOM   1188 O O   . TYR A 1 149 ? -47.844 39.842  -6.266  1.00 22.37 ? 151 TYR A O   1 
ATOM   1189 C CB  . TYR A 1 149 ? -50.224 41.269  -7.318  1.00 23.12 ? 151 TYR A CB  1 
ATOM   1190 C CG  . TYR A 1 149 ? -50.130 42.552  -6.518  1.00 28.78 ? 151 TYR A CG  1 
ATOM   1191 C CD1 . TYR A 1 149 ? -49.979 42.528  -5.138  1.00 30.37 ? 151 TYR A CD1 1 
ATOM   1192 C CD2 . TYR A 1 149 ? -50.236 43.786  -7.142  1.00 33.13 ? 151 TYR A CD2 1 
ATOM   1193 C CE1 . TYR A 1 149 ? -49.913 43.702  -4.406  1.00 29.31 ? 151 TYR A CE1 1 
ATOM   1194 C CE2 . TYR A 1 149 ? -50.172 44.969  -6.417  1.00 34.45 ? 151 TYR A CE2 1 
ATOM   1195 C CZ  . TYR A 1 149 ? -50.012 44.916  -5.049  1.00 35.19 ? 151 TYR A CZ  1 
ATOM   1196 O OH  . TYR A 1 149 ? -49.951 46.082  -4.315  1.00 40.40 ? 151 TYR A OH  1 
ATOM   1197 N N   . ILE A 1 150 ? -46.626 41.197  -7.599  1.00 21.52 ? 152 ILE A N   1 
ATOM   1198 C CA  . ILE A 1 150 ? -45.350 40.957  -6.935  1.00 22.31 ? 152 ILE A CA  1 
ATOM   1199 C C   . ILE A 1 150 ? -45.195 41.934  -5.778  1.00 25.89 ? 152 ILE A C   1 
ATOM   1200 O O   . ILE A 1 150 ? -45.268 43.156  -5.969  1.00 25.59 ? 152 ILE A O   1 
ATOM   1201 C CB  . ILE A 1 150 ? -44.177 41.100  -7.918  1.00 23.85 ? 152 ILE A CB  1 
ATOM   1202 C CG1 . ILE A 1 150 ? -44.318 40.144  -9.109  1.00 22.18 ? 152 ILE A CG1 1 
ATOM   1203 C CG2 . ILE A 1 150 ? -42.844 40.855  -7.194  1.00 24.69 ? 152 ILE A CG2 1 
ATOM   1204 C CD1 . ILE A 1 150 ? -44.250 38.691  -8.693  1.00 19.16 ? 152 ILE A CD1 1 
ATOM   1205 N N   . MET A 1 151 ? -44.947 41.391  -4.591  1.00 25.61 ? 153 MET A N   1 
ATOM   1206 C CA  . MET A 1 151 ? -44.769 42.143  -3.353  1.00 29.93 ? 153 MET A CA  1 
ATOM   1207 C C   . MET A 1 151 ? -43.390 41.838  -2.790  1.00 31.29 ? 153 MET A C   1 
ATOM   1208 O O   . MET A 1 151 ? -42.981 40.673  -2.751  1.00 31.62 ? 153 MET A O   1 
ATOM   1209 C CB  . MET A 1 151 ? -45.847 41.757  -2.340  1.00 28.36 ? 153 MET A CB  1 
ATOM   1210 C CG  . MET A 1 151 ? -47.260 42.044  -2.805  1.00 29.87 ? 153 MET A CG  1 
ATOM   1211 S SD  . MET A 1 151 ? -48.475 41.563  -1.580  1.00 41.62 ? 153 MET A SD  1 
ATOM   1212 C CE  . MET A 1 151 ? -48.709 39.829  -2.053  1.00 28.57 ? 153 MET A CE  1 
ATOM   1213 N N   . ALA A 1 152 ? -42.669 42.876  -2.371  1.00 30.07 ? 154 ALA A N   1 
ATOM   1214 C CA  . ALA A 1 152 ? -41.386 42.650  -1.721  1.00 32.93 ? 154 ALA A CA  1 
ATOM   1215 C C   . ALA A 1 152 ? -41.599 41.944  -0.391  1.00 35.14 ? 154 ALA A C   1 
ATOM   1216 O O   . ALA A 1 152 ? -42.576 42.202  0.317   1.00 36.23 ? 154 ALA A O   1 
ATOM   1217 C CB  . ALA A 1 152 ? -40.645 43.966  -1.506  1.00 36.51 ? 154 ALA A CB  1 
ATOM   1218 N N   . ASP A 1 153 ? -40.697 41.024  -0.067  1.00 37.70 ? 155 ASP A N   1 
ATOM   1219 C CA  . ASP A 1 153 ? -40.701 40.347  1.226   1.00 39.00 ? 155 ASP A CA  1 
ATOM   1220 C C   . ASP A 1 153 ? -39.342 40.733  1.801   1.00 44.08 ? 155 ASP A C   1 
ATOM   1221 O O   . ASP A 1 153 ? -38.342 40.043  1.580   1.00 42.49 ? 155 ASP A O   1 
ATOM   1222 C CB  . ASP A 1 153 ? -40.897 38.810  1.082   1.00 34.57 ? 155 ASP A CB  1 
ATOM   1223 C CG  . ASP A 1 153 ? -40.588 38.028  2.365   1.00 47.85 ? 155 ASP A CG  1 
ATOM   1224 O OD1 . ASP A 1 153 ? -39.947 38.554  3.299   1.00 51.47 ? 155 ASP A OD1 1 
ATOM   1225 O OD2 . ASP A 1 153 ? -41.011 36.852  2.441   1.00 51.38 ? 155 ASP A OD2 1 
ATOM   1226 N N   . LYS A 1 154 ? -39.301 41.873  2.498   1.00 47.15 ? 156 LYS A N   1 
ATOM   1227 C CA  . LYS A 1 154 ? -38.042 42.354  3.060   1.00 51.73 ? 156 LYS A CA  1 
ATOM   1228 C C   . LYS A 1 154 ? -37.450 41.346  4.035   1.00 50.65 ? 156 LYS A C   1 
ATOM   1229 O O   . LYS A 1 154 ? -36.224 41.270  4.184   1.00 52.35 ? 156 LYS A O   1 
ATOM   1230 C CB  . LYS A 1 154 ? -38.257 43.706  3.749   1.00 51.19 ? 156 LYS A CB  1 
ATOM   1231 C CG  . LYS A 1 154 ? -37.010 44.590  3.807   1.00 55.04 ? 156 LYS A CG  1 
ATOM   1232 C CD  . LYS A 1 154 ? -36.953 45.405  5.102   1.00 54.89 ? 156 LYS A CD  1 
ATOM   1233 C CE  . LYS A 1 154 ? -36.163 46.700  4.913   1.00 58.84 ? 156 LYS A CE  1 
ATOM   1234 N NZ  . LYS A 1 154 ? -36.476 47.735  5.948   1.00 51.51 ? 156 LYS A NZ  1 
ATOM   1235 N N   . GLN A 1 155 ? -38.307 40.550  4.679   1.00 50.04 ? 157 GLN A N   1 
ATOM   1236 C CA  . GLN A 1 155 ? -37.867 39.637  5.728   1.00 47.56 ? 157 GLN A CA  1 
ATOM   1237 C C   . GLN A 1 155 ? -36.958 38.548  5.170   1.00 52.03 ? 157 GLN A C   1 
ATOM   1238 O O   . GLN A 1 155 ? -35.885 38.276  5.723   1.00 52.60 ? 157 GLN A O   1 
ATOM   1239 C CB  . GLN A 1 155 ? -39.092 39.032  6.419   1.00 53.21 ? 157 GLN A CB  1 
ATOM   1240 C CG  . GLN A 1 155 ? -40.060 40.067  7.034   1.00 55.04 ? 157 GLN A CG  1 
ATOM   1241 C CD  . GLN A 1 155 ? -40.980 40.733  6.003   1.00 56.81 ? 157 GLN A CD  1 
ATOM   1242 O OE1 . GLN A 1 155 ? -40.556 41.620  5.254   1.00 55.41 ? 157 GLN A OE1 1 
ATOM   1243 N NE2 . GLN A 1 155 ? -42.242 40.308  5.966   1.00 54.96 ? 157 GLN A NE2 1 
ATOM   1244 N N   . LYS A 1 156 ? -37.369 37.910  4.076   1.00 48.60 ? 158 LYS A N   1 
ATOM   1245 C CA  . LYS A 1 156 ? -36.553 36.908  3.407   1.00 47.34 ? 158 LYS A CA  1 
ATOM   1246 C C   . LYS A 1 156 ? -35.789 37.485  2.218   1.00 44.60 ? 158 LYS A C   1 
ATOM   1247 O O   . LYS A 1 156 ? -35.292 36.727  1.377   1.00 43.40 ? 158 LYS A O   1 
ATOM   1248 C CB  . LYS A 1 156 ? -37.426 35.723  2.984   1.00 44.64 ? 158 LYS A CB  1 
ATOM   1249 C CG  . LYS A 1 156 ? -37.720 34.797  4.157   1.00 48.41 ? 158 LYS A CG  1 
ATOM   1250 C CD  . LYS A 1 156 ? -39.055 34.079  4.043   1.00 49.07 ? 158 LYS A CD  1 
ATOM   1251 C CE  . LYS A 1 156 ? -38.982 32.671  4.629   1.00 41.69 ? 158 LYS A CE  1 
ATOM   1252 N NZ  . LYS A 1 156 ? -40.253 32.334  5.333   1.00 40.35 ? 158 LYS A NZ  1 
ATOM   1253 N N   . ASN A 1 157 ? -35.682 38.815  2.144   1.00 44.77 ? 159 ASN A N   1 
ATOM   1254 C CA  . ASN A 1 157 ? -34.918 39.510  1.104   1.00 40.92 ? 159 ASN A CA  1 
ATOM   1255 C C   . ASN A 1 157 ? -35.331 39.114  -0.309  1.00 37.15 ? 159 ASN A C   1 
ATOM   1256 O O   . ASN A 1 157 ? -34.534 39.187  -1.243  1.00 38.77 ? 159 ASN A O   1 
ATOM   1257 C CB  . ASN A 1 157 ? -33.413 39.300  1.275   1.00 42.53 ? 159 ASN A CB  1 
ATOM   1258 C CG  . ASN A 1 157 ? -32.618 40.498  0.817   1.00 42.53 ? 159 ASN A CG  1 
ATOM   1259 O OD1 . ASN A 1 157 ? -33.119 41.621  0.817   1.00 50.49 ? 159 ASN A OD1 1 
ATOM   1260 N ND2 . ASN A 1 157 ? -31.382 40.265  0.394   1.00 48.89 ? 159 ASN A ND2 1 
ATOM   1261 N N   . GLY A 1 158 ? -36.583 38.729  -0.498  1.00 37.57 ? 160 GLY A N   1 
ATOM   1262 C CA  . GLY A 1 158 ? -37.026 38.412  -1.839  1.00 31.64 ? 160 GLY A CA  1 
ATOM   1263 C C   . GLY A 1 158 ? -38.394 38.969  -2.152  1.00 31.49 ? 160 GLY A C   1 
ATOM   1264 O O   . GLY A 1 158 ? -38.698 40.119  -1.823  1.00 29.24 ? 160 GLY A O   1 
ATOM   1265 N N   . ILE A 1 159 ? -39.234 38.159  -2.789  1.00 24.62 ? 161 ILE A N   1 
ATOM   1266 C CA  . ILE A 1 159 ? -40.573 38.578  -3.168  1.00 27.65 ? 161 ILE A CA  1 
ATOM   1267 C C   . ILE A 1 159 ? -41.549 37.459  -2.857  1.00 23.71 ? 161 ILE A C   1 
ATOM   1268 O O   . ILE A 1 159 ? -41.166 36.309  -2.622  1.00 21.46 ? 161 ILE A O   1 
ATOM   1269 C CB  . ILE A 1 159 ? -40.666 38.984  -4.655  1.00 24.54 ? 161 ILE A CB  1 
ATOM   1270 C CG1 . ILE A 1 159 ? -40.354 37.790  -5.568  1.00 21.26 ? 161 ILE A CG1 1 
ATOM   1271 C CG2 . ILE A 1 159 ? -39.738 40.161  -4.947  1.00 25.32 ? 161 ILE A CG2 1 
ATOM   1272 C CD1 . ILE A 1 159 ? -41.568 37.196  -6.237  1.00 23.36 ? 161 ILE A CD1 1 
ATOM   1273 N N   . LYS A 1 160 ? -42.829 37.827  -2.832  1.00 23.50 ? 162 LYS A N   1 
ATOM   1274 C CA  . LYS A 1 160 ? -43.901 36.859  -2.724  1.00 21.54 ? 162 LYS A CA  1 
ATOM   1275 C C   . LYS A 1 160 ? -45.049 37.290  -3.621  1.00 18.99 ? 162 LYS A C   1 
ATOM   1276 O O   . LYS A 1 160 ? -45.146 38.442  -4.051  1.00 22.98 ? 162 LYS A O   1 
ATOM   1277 C CB  . LYS A 1 160 ? -44.394 36.675  -1.278  1.00 24.59 ? 162 LYS A CB  1 
ATOM   1278 C CG  . LYS A 1 160 ? -44.501 37.946  -0.459  1.00 32.98 ? 162 LYS A CG  1 
ATOM   1279 C CD  . LYS A 1 160 ? -45.309 37.719  0.837   1.00 37.23 ? 162 LYS A CD  1 
ATOM   1280 C CE  . LYS A 1 160 ? -45.052 36.339  1.471   1.00 36.89 ? 162 LYS A CE  1 
ATOM   1281 N NZ  . LYS A 1 160 ? -43.645 36.109  1.922   1.00 38.51 ? 162 LYS A NZ  1 
ATOM   1282 N N   . ALA A 1 161 ? -45.906 36.326  -3.922  1.00 18.52 ? 163 ALA A N   1 
ATOM   1283 C CA  . ALA A 1 161 ? -47.098 36.586  -4.709  1.00 18.80 ? 163 ALA A CA  1 
ATOM   1284 C C   . ALA A 1 161 ? -48.036 35.421  -4.486  1.00 18.00 ? 163 ALA A C   1 
ATOM   1285 O O   . ALA A 1 161 ? -47.600 34.321  -4.139  1.00 20.05 ? 163 ALA A O   1 
ATOM   1286 C CB  . ALA A 1 161 ? -46.775 36.762  -6.201  1.00 18.22 ? 163 ALA A CB  1 
ATOM   1287 N N   . ASN A 1 162 ? -49.331 35.676  -4.637  1.00 15.95 ? 164 ASN A N   1 
ATOM   1288 C CA  . ASN A 1 162 ? -50.295 34.589  -4.660  1.00 16.89 ? 164 ASN A CA  1 
ATOM   1289 C C   . ASN A 1 162 ? -51.392 34.954  -5.644  1.00 18.35 ? 164 ASN A C   1 
ATOM   1290 O O   . ASN A 1 162 ? -51.775 36.124  -5.744  1.00 17.38 ? 164 ASN A O   1 
ATOM   1291 C CB  . ASN A 1 162 ? -50.864 34.272  -3.265  1.00 17.50 ? 164 ASN A CB  1 
ATOM   1292 C CG  . ASN A 1 162 ? -51.681 35.414  -2.684  1.00 19.40 ? 164 ASN A CG  1 
ATOM   1293 O OD1 . ASN A 1 162 ? -52.894 35.308  -2.576  1.00 25.21 ? 164 ASN A OD1 1 
ATOM   1294 N ND2 . ASN A 1 162 ? -51.008 36.463  -2.224  1.00 17.45 ? 164 ASN A ND2 1 
ATOM   1295 N N   . PHE A 1 163 ? -51.841 33.968  -6.417  1.00 16.15 ? 165 PHE A N   1 
ATOM   1296 C CA  . PHE A 1 163 ? -52.750 34.246  -7.517  1.00 17.84 ? 165 PHE A CA  1 
ATOM   1297 C C   . PHE A 1 163 ? -53.454 32.957  -7.911  1.00 19.22 ? 165 PHE A C   1 
ATOM   1298 O O   . PHE A 1 163 ? -52.969 31.857  -7.641  1.00 19.63 ? 165 PHE A O   1 
ATOM   1299 C CB  . PHE A 1 163 ? -52.000 34.847  -8.714  1.00 15.47 ? 165 PHE A CB  1 
ATOM   1300 C CG  . PHE A 1 163 ? -50.838 34.011  -9.190  1.00 16.42 ? 165 PHE A CG  1 
ATOM   1301 C CD1 . PHE A 1 163 ? -49.582 34.120  -8.599  1.00 13.31 ? 165 PHE A CD1 1 
ATOM   1302 C CD2 . PHE A 1 163 ? -51.003 33.130  -10.260 1.00 14.39 ? 165 PHE A CD2 1 
ATOM   1303 C CE1 . PHE A 1 163 ? -48.519 33.344  -9.048  1.00 16.63 ? 165 PHE A CE1 1 
ATOM   1304 C CE2 . PHE A 1 163 ? -49.947 32.354  -10.713 1.00 16.46 ? 165 PHE A CE2 1 
ATOM   1305 C CZ  . PHE A 1 163 ? -48.700 32.465  -10.107 1.00 16.49 ? 165 PHE A CZ  1 
ATOM   1306 N N   . LYS A 1 164 ? -54.603 33.105  -8.565  1.00 21.16 ? 166 LYS A N   1 
ATOM   1307 C CA  . LYS A 1 164 ? -55.379 31.975  -9.063  1.00 20.38 ? 166 LYS A CA  1 
ATOM   1308 C C   . LYS A 1 164 ? -55.092 31.747  -10.545 1.00 22.71 ? 166 LYS A C   1 
ATOM   1309 O O   . LYS A 1 164 ? -54.895 32.701  -11.303 1.00 24.12 ? 166 LYS A O   1 
ATOM   1310 C CB  . LYS A 1 164 ? -56.887 32.211  -8.872  1.00 27.83 ? 166 LYS A CB  1 
ATOM   1311 C CG  . LYS A 1 164 ? -57.291 33.084  -7.679  1.00 33.78 ? 166 LYS A CG  1 
ATOM   1312 C CD  . LYS A 1 164 ? -58.503 34.025  -7.984  1.00 42.05 ? 166 LYS A CD  1 
ATOM   1313 C CE  . LYS A 1 164 ? -58.113 35.318  -8.755  1.00 40.05 ? 166 LYS A CE  1 
ATOM   1314 N NZ  . LYS A 1 164 ? -59.283 36.155  -9.213  1.00 34.22 ? 166 LYS A NZ  1 
ATOM   1315 N N   . ILE A 1 165 ? -55.047 30.479  -10.950 1.00 17.84 ? 167 ILE A N   1 
ATOM   1316 C CA  . ILE A 1 165 ? -55.032 30.086  -12.354 1.00 16.84 ? 167 ILE A CA  1 
ATOM   1317 C C   . ILE A 1 165 ? -56.260 29.224  -12.596 1.00 18.51 ? 167 ILE A C   1 
ATOM   1318 O O   . ILE A 1 165 ? -56.581 28.364  -11.772 1.00 18.25 ? 167 ILE A O   1 
ATOM   1319 C CB  . ILE A 1 165 ? -53.751 29.314  -12.735 1.00 15.45 ? 167 ILE A CB  1 
ATOM   1320 C CG1 . ILE A 1 165 ? -52.521 30.199  -12.566 1.00 13.74 ? 167 ILE A CG1 1 
ATOM   1321 C CG2 . ILE A 1 165 ? -53.852 28.763  -14.172 1.00 18.47 ? 167 ILE A CG2 1 
ATOM   1322 C CD1 . ILE A 1 165 ? -52.391 31.248  -13.648 1.00 16.93 ? 167 ILE A CD1 1 
ATOM   1323 N N   . ARG A 1 166 ? -56.953 29.458  -13.713 1.00 17.77 ? 168 ARG A N   1 
ATOM   1324 C CA  . ARG A 1 166 ? -58.172 28.732  -14.053 1.00 19.88 ? 168 ARG A CA  1 
ATOM   1325 C C   . ARG A 1 166 ? -57.878 27.791  -15.214 1.00 18.74 ? 168 ARG A C   1 
ATOM   1326 O O   . ARG A 1 166 ? -57.391 28.239  -16.254 1.00 20.81 ? 168 ARG A O   1 
ATOM   1327 C CB  . ARG A 1 166 ? -59.272 29.710  -14.471 1.00 24.86 ? 168 ARG A CB  1 
ATOM   1328 C CG  . ARG A 1 166 ? -60.231 30.111  -13.393 1.00 28.75 ? 168 ARG A CG  1 
ATOM   1329 C CD  . ARG A 1 166 ? -59.811 31.414  -12.827 1.00 33.15 ? 168 ARG A CD  1 
ATOM   1330 N NE  . ARG A 1 166 ? -60.793 31.958  -11.901 1.00 40.30 ? 168 ARG A NE  1 
ATOM   1331 C CZ  . ARG A 1 166 ? -60.565 33.016  -11.136 1.00 43.45 ? 168 ARG A CZ  1 
ATOM   1332 N NH1 . ARG A 1 166 ? -59.398 33.644  -11.161 1.00 39.37 ? 168 ARG A NH1 1 
ATOM   1333 N NH2 . ARG A 1 166 ? -61.522 33.442  -10.314 1.00 42.44 ? 168 ARG A NH2 1 
ATOM   1334 N N   . HIS A 1 167 ? -58.189 26.503  -15.054 1.00 16.87 ? 169 HIS A N   1 
ATOM   1335 C CA  . HIS A 1 167 ? -57.964 25.507  -16.097 1.00 17.69 ? 169 HIS A CA  1 
ATOM   1336 C C   . HIS A 1 167 ? -59.318 25.028  -16.612 1.00 19.85 ? 169 HIS A C   1 
ATOM   1337 O O   . HIS A 1 167 ? -60.136 24.530  -15.833 1.00 20.04 ? 169 HIS A O   1 
ATOM   1338 C CB  . HIS A 1 167 ? -57.179 24.310  -15.551 1.00 20.09 ? 169 HIS A CB  1 
ATOM   1339 C CG  . HIS A 1 167 ? -55.772 24.634  -15.163 1.00 16.30 ? 169 HIS A CG  1 
ATOM   1340 N ND1 . HIS A 1 167 ? -54.829 25.086  -16.060 1.00 16.81 ? 169 HIS A ND1 1 
ATOM   1341 C CD2 . HIS A 1 167 ? -55.148 24.556  -13.965 1.00 17.53 ? 169 HIS A CD2 1 
ATOM   1342 C CE1 . HIS A 1 167 ? -53.685 25.291  -15.424 1.00 17.60 ? 169 HIS A CE1 1 
ATOM   1343 N NE2 . HIS A 1 167 ? -53.855 24.983  -14.150 1.00 16.69 ? 169 HIS A NE2 1 
ATOM   1344 N N   . ASN A 1 168 ? -59.544 25.144  -17.916 1.00 17.92 ? 170 ASN A N   1 
ATOM   1345 C CA  . ASN A 1 168 ? -60.814 24.705  -18.486 1.00 20.50 ? 170 ASN A CA  1 
ATOM   1346 C C   . ASN A 1 168 ? -60.959 23.190  -18.393 1.00 23.71 ? 170 ASN A C   1 
ATOM   1347 O O   . ASN A 1 168 ? -60.065 22.440  -18.799 1.00 24.29 ? 170 ASN A O   1 
ATOM   1348 C CB  . ASN A 1 168 ? -60.901 25.139  -19.945 1.00 26.13 ? 170 ASN A CB  1 
ATOM   1349 C CG  . ASN A 1 168 ? -61.105 26.621  -20.093 1.00 22.67 ? 170 ASN A CG  1 
ATOM   1350 O OD1 . ASN A 1 168 ? -61.929 27.217  -19.412 1.00 27.89 ? 170 ASN A OD1 1 
ATOM   1351 N ND2 . ASN A 1 168 ? -60.324 27.235  -20.962 1.00 33.66 ? 170 ASN A ND2 1 
ATOM   1352 N N   . ILE A 1 169 ? -62.093 22.737  -17.870 1.00 24.62 ? 171 ILE A N   1 
ATOM   1353 C CA  . ILE A 1 169 ? -62.389 21.309  -17.757 1.00 22.13 ? 171 ILE A CA  1 
ATOM   1354 C C   . ILE A 1 169 ? -63.122 20.853  -19.011 1.00 27.30 ? 171 ILE A C   1 
ATOM   1355 O O   . ILE A 1 169 ? -64.042 21.525  -19.500 1.00 21.44 ? 171 ILE A O   1 
ATOM   1356 C CB  . ILE A 1 169 ? -63.222 21.006  -16.494 1.00 25.22 ? 171 ILE A CB  1 
ATOM   1357 C CG1 . ILE A 1 169 ? -62.511 21.485  -15.220 1.00 21.52 ? 171 ILE A CG1 1 
ATOM   1358 C CG2 . ILE A 1 169 ? -63.516 19.512  -16.390 1.00 25.01 ? 171 ILE A CG2 1 
ATOM   1359 N N   . GLU A 1 170 ? -62.755 19.694  -19.519 1.00 27.19 ? 172 GLU A N   1 
ATOM   1360 C CA  . GLU A 1 170 ? -63.308 19.194  -20.752 1.00 33.58 ? 172 GLU A CA  1 
ATOM   1361 C C   . GLU A 1 170 ? -64.812 19.155  -20.873 1.00 31.49 ? 172 GLU A C   1 
ATOM   1362 O O   . GLU A 1 170 ? -65.372 19.677  -21.806 1.00 39.90 ? 172 GLU A O   1 
ATOM   1363 C CB  . GLU A 1 170 ? -62.701 17.860  -21.163 1.00 36.32 ? 172 GLU A CB  1 
ATOM   1364 C CG  . GLU A 1 170 ? -61.351 18.052  -21.826 1.00 36.89 ? 172 GLU A CG  1 
ATOM   1365 C CD  . GLU A 1 170 ? -60.603 16.748  -22.156 1.00 40.35 ? 172 GLU A CD  1 
ATOM   1366 O OE1 . GLU A 1 170 ? -60.965 15.687  -21.657 1.00 39.57 ? 172 GLU A OE1 1 
ATOM   1367 O OE2 . GLU A 1 170 ? -59.615 16.813  -22.899 1.00 41.71 ? 172 GLU A OE2 1 
ATOM   1368 N N   . ASP A 1 171 ? -65.512 18.594  -19.955 1.00 35.30 ? 173 ASP A N   1 
ATOM   1369 C CA  . ASP A 1 171 ? -66.919 18.740  -20.257 1.00 38.61 ? 173 ASP A CA  1 
ATOM   1370 C C   . ASP A 1 171 ? -67.647 19.686  -19.384 1.00 30.39 ? 173 ASP A C   1 
ATOM   1371 O O   . ASP A 1 171 ? -68.764 19.472  -18.986 1.00 26.63 ? 173 ASP A O   1 
ATOM   1372 C CB  . ASP A 1 171 ? -67.613 17.447  -20.394 1.00 41.39 ? 173 ASP A CB  1 
ATOM   1373 C CG  . ASP A 1 171 ? -67.146 16.567  -19.464 1.00 43.81 ? 173 ASP A CG  1 
ATOM   1374 O OD1 . ASP A 1 171 ? -66.996 17.121  -18.375 1.00 41.96 ? 173 ASP A OD1 1 
ATOM   1375 O OD2 . ASP A 1 171 ? -66.911 15.400  -19.819 1.00 44.81 ? 173 ASP A OD2 1 
ATOM   1376 N N   . GLY A 1 172 ? -66.980 20.784  -19.144 1.00 25.16 ? 174 GLY A N   1 
ATOM   1377 C CA  . GLY A 1 172 ? -67.613 21.890  -18.514 1.00 24.37 ? 174 GLY A CA  1 
ATOM   1378 C C   . GLY A 1 172 ? -66.955 22.515  -17.332 1.00 27.17 ? 174 GLY A C   1 
ATOM   1379 O O   . GLY A 1 172 ? -66.436 21.869  -16.527 1.00 25.24 ? 174 GLY A O   1 
ATOM   1380 N N   . GLY A 1 173 ? -67.035 23.812  -17.244 1.00 16.62 ? 175 GLY A N   1 
ATOM   1381 C CA  . GLY A 1 173 ? -66.512 24.419  -16.051 1.00 32.37 ? 175 GLY A CA  1 
ATOM   1382 C C   . GLY A 1 173 ? -65.026 24.564  -15.982 1.00 27.71 ? 175 GLY A C   1 
ATOM   1383 O O   . GLY A 1 173 ? -64.352 24.386  -16.934 1.00 19.30 ? 175 GLY A O   1 
ATOM   1384 N N   . VAL A 1 174 ? -64.582 24.869  -14.781 1.00 23.40 ? 176 VAL A N   1 
ATOM   1385 C CA  . VAL A 1 174 ? -63.250 25.432  -14.626 1.00 22.44 ? 176 VAL A CA  1 
ATOM   1386 C C   . VAL A 1 174 ? -62.628 24.781  -13.395 1.00 25.73 ? 176 VAL A C   1 
ATOM   1387 O O   . VAL A 1 174 ? -63.324 24.520  -12.408 1.00 21.46 ? 176 VAL A O   1 
ATOM   1388 C CB  . VAL A 1 174 ? -63.292 26.963  -14.509 1.00 21.42 ? 176 VAL A CB  1 
ATOM   1389 C CG1 . VAL A 1 174 ? -62.044 27.440  -13.903 1.00 26.62 ? 176 VAL A CG1 1 
ATOM   1390 C CG2 . VAL A 1 174 ? -63.444 27.596  -15.903 1.00 24.91 ? 176 VAL A CG2 1 
ATOM   1391 N N   . GLN A 1 175 ? -61.337 24.461  -13.479 1.00 20.86 ? 177 GLN A N   1 
ATOM   1392 C CA  . GLN A 1 175 ? -60.591 23.860  -12.380 1.00 20.14 ? 177 GLN A CA  1 
ATOM   1393 C C   . GLN A 1 175 ? -59.636 24.913  -11.831 1.00 20.30 ? 177 GLN A C   1 
ATOM   1394 O O   . GLN A 1 175 ? -58.759 25.394  -12.558 1.00 18.06 ? 177 GLN A O   1 
ATOM   1395 C CB  . GLN A 1 175 ? -59.817 22.628  -12.860 1.00 20.30 ? 177 GLN A CB  1 
ATOM   1396 C CG  . GLN A 1 175 ? -58.745 22.128  -11.895 1.00 20.34 ? 177 GLN A CG  1 
ATOM   1397 C CD  . GLN A 1 175 ? -59.368 21.448  -10.698 1.00 18.86 ? 177 GLN A CD  1 
ATOM   1398 O OE1 . GLN A 1 175 ? -60.000 20.404  -10.834 1.00 22.64 ? 177 GLN A OE1 1 
ATOM   1399 N NE2 . GLN A 1 175 ? -59.182 22.024  -9.512  1.00 23.08 ? 177 GLN A NE2 1 
ATOM   1400 N N   . LEU A 1 176 ? -59.817 25.283  -10.562 1.00 17.67 ? 178 LEU A N   1 
ATOM   1401 C CA  . LEU A 1 176 ? -59.005 26.325  -9.949  1.00 17.33 ? 178 LEU A CA  1 
ATOM   1402 C C   . LEU A 1 176 ? -57.680 25.768  -9.451  1.00 17.51 ? 178 LEU A C   1 
ATOM   1403 O O   . LEU A 1 176 ? -57.632 24.671  -8.891  1.00 18.15 ? 178 LEU A O   1 
ATOM   1404 C CB  . LEU A 1 176 ? -59.736 26.977  -8.773  1.00 19.28 ? 178 LEU A CB  1 
ATOM   1405 C CG  . LEU A 1 176 ? -60.434 28.295  -9.114  1.00 30.77 ? 178 LEU A CG  1 
ATOM   1406 C CD1 . LEU A 1 176 ? -59.381 29.404  -9.179  1.00 30.22 ? 178 LEU A CD1 1 
ATOM   1407 C CD2 . LEU A 1 176 ? -61.250 28.231  -10.402 1.00 32.98 ? 178 LEU A CD2 1 
ATOM   1408 N N   . ALA A 1 177 ? -56.609 26.541  -9.656  1.00 12.42 ? 179 ALA A N   1 
ATOM   1409 C CA  . ALA A 1 177 ? -55.261 26.204  -9.190  1.00 14.78 ? 179 ALA A CA  1 
ATOM   1410 C C   . ALA A 1 177 ? -54.746 27.404  -8.407  1.00 14.34 ? 179 ALA A C   1 
ATOM   1411 O O   . ALA A 1 177 ? -54.303 28.398  -8.992  1.00 13.83 ? 179 ALA A O   1 
ATOM   1412 C CB  . ALA A 1 177 ? -54.339 25.853  -10.356 1.00 13.03 ? 179 ALA A CB  1 
ATOM   1413 N N   . ASP A 1 178 ? -54.814 27.304  -7.081  1.00 13.73 ? 180 ASP A N   1 
ATOM   1414 C CA  . ASP A 1 178 ? -54.490 28.403  -6.180  1.00 15.44 ? 180 ASP A CA  1 
ATOM   1415 C C   . ASP A 1 178 ? -52.989 28.406  -5.910  1.00 15.81 ? 180 ASP A C   1 
ATOM   1416 O O   . ASP A 1 178 ? -52.470 27.491  -5.269  1.00 15.69 ? 180 ASP A O   1 
ATOM   1417 C CB  . ASP A 1 178 ? -55.311 28.250  -4.899  1.00 16.46 ? 180 ASP A CB  1 
ATOM   1418 C CG  . ASP A 1 178 ? -55.303 29.492  -4.051  1.00 20.94 ? 180 ASP A CG  1 
ATOM   1419 O OD1 . ASP A 1 178 ? -55.774 29.421  -2.894  1.00 27.25 ? 180 ASP A OD1 1 
ATOM   1420 O OD2 . ASP A 1 178 ? -54.770 30.519  -4.509  1.00 24.07 ? 180 ASP A OD2 1 
ATOM   1421 N N   . HIS A 1 179 ? -52.301 29.434  -6.400  1.00 15.12 ? 181 HIS A N   1 
ATOM   1422 C CA  . HIS A 1 179 ? -50.846 29.532  -6.360  1.00 15.32 ? 181 HIS A CA  1 
ATOM   1423 C C   . HIS A 1 179 ? -50.385 30.408  -5.203  1.00 15.54 ? 181 HIS A C   1 
ATOM   1424 O O   . HIS A 1 179 ? -50.835 31.551  -5.071  1.00 14.12 ? 181 HIS A O   1 
ATOM   1425 C CB  . HIS A 1 179 ? -50.308 30.137  -7.660  1.00 14.85 ? 181 HIS A CB  1 
ATOM   1426 C CG  . HIS A 1 179 ? -50.289 29.197  -8.831  1.00 16.23 ? 181 HIS A CG  1 
ATOM   1427 N ND1 . HIS A 1 179 ? -51.430 28.630  -9.358  1.00 15.77 ? 181 HIS A ND1 1 
ATOM   1428 C CD2 . HIS A 1 179 ? -49.267 28.786  -9.620  1.00 12.32 ? 181 HIS A CD2 1 
ATOM   1429 C CE1 . HIS A 1 179 ? -51.106 27.878  -10.397 1.00 15.03 ? 181 HIS A CE1 1 
ATOM   1430 N NE2 . HIS A 1 179 ? -49.800 27.957  -10.577 1.00 14.18 ? 181 HIS A NE2 1 
ATOM   1431 N N   . TYR A 1 180 ? -49.425 29.908  -4.427  1.00 13.40 ? 182 TYR A N   1 
ATOM   1432 C CA  . TYR A 1 180 ? -48.699 30.713  -3.453  1.00 14.98 ? 182 TYR A CA  1 
ATOM   1433 C C   . TYR A 1 180 ? -47.217 30.627  -3.781  1.00 16.27 ? 182 TYR A C   1 
ATOM   1434 O O   . TYR A 1 180 ? -46.723 29.552  -4.118  1.00 17.62 ? 182 TYR A O   1 
ATOM   1435 C CB  . TYR A 1 180 ? -48.966 30.223  -2.028  1.00 17.99 ? 182 TYR A CB  1 
ATOM   1436 C CG  . TYR A 1 180 ? -50.432 30.273  -1.714  1.00 15.13 ? 182 TYR A CG  1 
ATOM   1437 C CD1 . TYR A 1 180 ? -51.271 29.241  -2.095  1.00 15.04 ? 182 TYR A CD1 1 
ATOM   1438 C CD2 . TYR A 1 180 ? -50.994 31.399  -1.120  1.00 17.55 ? 182 TYR A CD2 1 
ATOM   1439 C CE1 . TYR A 1 180 ? -52.623 29.300  -1.849  1.00 16.19 ? 182 TYR A CE1 1 
ATOM   1440 C CE2 . TYR A 1 180 ? -52.344 31.477  -0.878  1.00 17.73 ? 182 TYR A CE2 1 
ATOM   1441 C CZ  . TYR A 1 180 ? -53.156 30.420  -1.239  1.00 20.76 ? 182 TYR A CZ  1 
ATOM   1442 O OH  . TYR A 1 180 ? -54.507 30.478  -0.996  1.00 22.15 ? 182 TYR A OH  1 
ATOM   1443 N N   . GLN A 1 181 ? -46.518 31.757  -3.722  1.00 15.09 ? 183 GLN A N   1 
ATOM   1444 C CA  . GLN A 1 181 ? -45.161 31.830  -4.259  1.00 17.11 ? 183 GLN A CA  1 
ATOM   1445 C C   . GLN A 1 181 ? -44.268 32.657  -3.354  1.00 17.31 ? 183 GLN A C   1 
ATOM   1446 O O   . GLN A 1 181 ? -44.687 33.698  -2.847  1.00 18.52 ? 183 GLN A O   1 
ATOM   1447 C CB  . GLN A 1 181 ? -45.167 32.444  -5.669  1.00 15.79 ? 183 GLN A CB  1 
ATOM   1448 C CG  . GLN A 1 181 ? -43.786 32.618  -6.293  1.00 16.94 ? 183 GLN A CG  1 
ATOM   1449 C CD  . GLN A 1 181 ? -43.832 33.198  -7.710  1.00 17.25 ? 183 GLN A CD  1 
ATOM   1450 O OE1 . GLN A 1 181 ? -44.867 33.173  -8.389  1.00 14.60 ? 183 GLN A OE1 1 
ATOM   1451 N NE2 . GLN A 1 181 ? -42.691 33.712  -8.168  1.00 17.57 ? 183 GLN A NE2 1 
ATOM   1452 N N   . GLN A 1 182 ? -43.020 32.216  -3.177  1.00 18.63 ? 184 GLN A N   1 
ATOM   1453 C CA  . GLN A 1 182 ? -42.010 33.059  -2.552  1.00 18.05 ? 184 GLN A CA  1 
ATOM   1454 C C   . GLN A 1 182 ? -40.667 32.830  -3.232  1.00 19.45 ? 184 GLN A C   1 
ATOM   1455 O O   . GLN A 1 182 ? -40.311 31.695  -3.556  1.00 17.79 ? 184 GLN A O   1 
ATOM   1456 C CB  . GLN A 1 182 ? -41.862 32.810  -1.033  1.00 20.93 ? 184 GLN A CB  1 
ATOM   1457 C CG  . GLN A 1 182 ? -41.165 31.521  -0.640  1.00 23.32 ? 184 GLN A CG  1 
ATOM   1458 C CD  . GLN A 1 182 ? -41.451 31.079  0.805   1.00 30.31 ? 184 GLN A CD  1 
ATOM   1459 O OE1 . GLN A 1 182 ? -42.100 31.795  1.577   1.00 29.59 ? 184 GLN A OE1 1 
ATOM   1460 N NE2 . GLN A 1 182 ? -40.922 29.914  1.183   1.00 28.39 ? 184 GLN A NE2 1 
ATOM   1461 N N   . ASN A 1 183 ? -39.937 33.915  -3.451  1.00 16.84 ? 185 ASN A N   1 
ATOM   1462 C CA  . ASN A 1 183 ? -38.623 33.866  -4.075  1.00 18.37 ? 185 ASN A CA  1 
ATOM   1463 C C   . ASN A 1 183 ? -37.572 34.481  -3.164  1.00 21.41 ? 185 ASN A C   1 
ATOM   1464 O O   . ASN A 1 183 ? -37.799 35.535  -2.560  1.00 20.53 ? 185 ASN A O   1 
ATOM   1465 C CB  . ASN A 1 183 ? -38.611 34.584  -5.411  1.00 19.82 ? 185 ASN A CB  1 
ATOM   1466 C CG  . ASN A 1 183 ? -39.399 33.849  -6.471  1.00 16.87 ? 185 ASN A CG  1 
ATOM   1467 O OD1 . ASN A 1 183 ? -40.463 33.309  -6.200  1.00 20.11 ? 185 ASN A OD1 1 
ATOM   1468 N ND2 . ASN A 1 183 ? -38.863 33.811  -7.688  1.00 16.52 ? 185 ASN A ND2 1 
ATOM   1469 N N   . THR A 1 184 ? -36.415 33.819  -3.079  1.00 21.99 ? 186 THR A N   1 
ATOM   1470 C CA  . THR A 1 184 ? -35.300 34.292  -2.274  1.00 25.43 ? 186 THR A CA  1 
ATOM   1471 C C   . THR A 1 184 ? -33.994 34.184  -3.053  1.00 23.46 ? 186 THR A C   1 
ATOM   1472 O O   . THR A 1 184 ? -33.760 33.191  -3.757  1.00 21.88 ? 186 THR A O   1 
ATOM   1473 C CB  . THR A 1 184 ? -35.186 33.507  -0.952  1.00 28.50 ? 186 THR A CB  1 
ATOM   1474 O OG1 . THR A 1 184 ? -34.757 32.169  -1.213  1.00 30.92 ? 186 THR A OG1 1 
ATOM   1475 C CG2 . THR A 1 184 ? -36.516 33.469  -0.218  1.00 31.82 ? 186 THR A CG2 1 
ATOM   1476 N N   . PRO A 1 185 ? -33.126 35.186  -2.954  1.00 22.92 ? 187 PRO A N   1 
ATOM   1477 C CA  . PRO A 1 185 ? -31.852 35.131  -3.681  1.00 22.53 ? 187 PRO A CA  1 
ATOM   1478 C C   . PRO A 1 185 ? -30.979 33.987  -3.184  1.00 24.18 ? 187 PRO A C   1 
ATOM   1479 O O   . PRO A 1 185 ? -31.054 33.568  -2.025  1.00 23.01 ? 187 PRO A O   1 
ATOM   1480 C CB  . PRO A 1 185 ? -31.203 36.493  -3.397  1.00 25.99 ? 187 PRO A CB  1 
ATOM   1481 C CG  . PRO A 1 185 ? -31.984 37.116  -2.293  1.00 30.82 ? 187 PRO A CG  1 
ATOM   1482 C CD  . PRO A 1 185 ? -33.298 36.417  -2.166  1.00 27.92 ? 187 PRO A CD  1 
ATOM   1483 N N   . ILE A 1 186 ? -30.165 33.453  -4.091  1.00 22.20 ? 188 ILE A N   1 
ATOM   1484 C CA  . ILE A 1 186 ? -29.236 32.402  -3.691  1.00 23.42 ? 188 ILE A CA  1 
ATOM   1485 C C   . ILE A 1 186 ? -27.940 33.009  -3.175  1.00 27.90 ? 188 ILE A C   1 
ATOM   1486 O O   . ILE A 1 186 ? -27.400 32.571  -2.157  1.00 28.41 ? 188 ILE A O   1 
ATOM   1487 C CB  . ILE A 1 186 ? -28.973 31.435  -4.865  1.00 26.38 ? 188 ILE A CB  1 
ATOM   1488 C CG1 . ILE A 1 186 ? -30.220 30.605  -5.173  1.00 16.92 ? 188 ILE A CG1 1 
ATOM   1489 C CG2 . ILE A 1 186 ? -27.814 30.499  -4.519  1.00 28.86 ? 188 ILE A CG2 1 
ATOM   1490 C CD1 . ILE A 1 186 ? -30.089 29.726  -6.399  1.00 21.17 ? 188 ILE A CD1 1 
ATOM   1491 N N   . GLY A 1 187 ? -27.448 34.034  -3.861  1.00 28.53 ? 189 GLY A N   1 
ATOM   1492 C CA  . GLY A 1 187 ? -26.210 34.674  -3.491  1.00 38.60 ? 189 GLY A CA  1 
ATOM   1493 C C   . GLY A 1 187 ? -26.359 35.546  -2.260  1.00 42.86 ? 189 GLY A C   1 
ATOM   1494 O O   . GLY A 1 187 ? -27.409 35.619  -1.618  1.00 36.83 ? 189 GLY A O   1 
ATOM   1495 N N   . ASP A 1 188 ? -25.257 36.218  -1.926  1.00 45.71 ? 190 ASP A N   1 
ATOM   1496 C CA  . ASP A 1 188 ? -25.228 37.156  -0.818  1.00 48.81 ? 190 ASP A CA  1 
ATOM   1497 C C   . ASP A 1 188 ? -25.226 38.607  -1.262  1.00 48.62 ? 190 ASP A C   1 
ATOM   1498 O O   . ASP A 1 188 ? -25.561 39.480  -0.455  1.00 50.32 ? 190 ASP A O   1 
ATOM   1499 C CB  . ASP A 1 188 ? -23.994 36.904  0.057   1.00 50.92 ? 190 ASP A CB  1 
ATOM   1500 C CG  . ASP A 1 188 ? -23.965 35.501  0.618   1.00 55.04 ? 190 ASP A CG  1 
ATOM   1501 O OD1 . ASP A 1 188 ? -23.318 34.631  -0.005  1.00 59.47 ? 190 ASP A OD1 1 
ATOM   1502 O OD2 . ASP A 1 188 ? -24.576 35.270  1.684   1.00 52.18 ? 190 ASP A OD2 1 
ATOM   1503 N N   . GLY A 1 189 ? -24.865 38.882  -2.513  1.00 51.96 ? 191 GLY A N   1 
ATOM   1504 C CA  . GLY A 1 189 ? -24.820 40.230  -3.024  1.00 49.37 ? 191 GLY A CA  1 
ATOM   1505 C C   . GLY A 1 189 ? -26.144 40.948  -2.873  1.00 49.02 ? 191 GLY A C   1 
ATOM   1506 O O   . GLY A 1 189 ? -27.179 40.342  -2.574  1.00 49.24 ? 191 GLY A O   1 
ATOM   1507 N N   . PRO A 1 190 ? -26.136 42.260  -3.074  1.00 46.91 ? 192 PRO A N   1 
ATOM   1508 C CA  . PRO A 1 190 ? -27.365 43.033  -2.893  1.00 47.87 ? 192 PRO A CA  1 
ATOM   1509 C C   . PRO A 1 190 ? -28.399 42.691  -3.950  1.00 45.80 ? 192 PRO A C   1 
ATOM   1510 O O   . PRO A 1 190 ? -28.082 42.242  -5.056  1.00 46.30 ? 192 PRO A O   1 
ATOM   1511 C CB  . PRO A 1 190 ? -26.895 44.487  -3.023  1.00 44.99 ? 192 PRO A CB  1 
ATOM   1512 C CG  . PRO A 1 190 ? -25.673 44.410  -3.855  1.00 45.78 ? 192 PRO A CG  1 
ATOM   1513 C CD  . PRO A 1 190 ? -25.011 43.103  -3.513  1.00 49.57 ? 192 PRO A CD  1 
ATOM   1514 N N   . VAL A 1 191 ? -29.654 42.926  -3.589  1.00 42.37 ? 193 VAL A N   1 
ATOM   1515 C CA  . VAL A 1 191 ? -30.801 42.555  -4.403  1.00 42.87 ? 193 VAL A CA  1 
ATOM   1516 C C   . VAL A 1 191 ? -31.826 43.683  -4.362  1.00 42.09 ? 193 VAL A C   1 
ATOM   1517 O O   . VAL A 1 191 ? -32.045 44.302  -3.314  1.00 46.26 ? 193 VAL A O   1 
ATOM   1518 C CB  . VAL A 1 191 ? -31.380 41.213  -3.914  1.00 41.09 ? 193 VAL A CB  1 
ATOM   1519 C CG1 . VAL A 1 191 ? -32.854 41.185  -4.082  1.00 42.35 ? 193 VAL A CG1 1 
ATOM   1520 C CG2 . VAL A 1 191 ? -30.755 40.073  -4.719  1.00 31.30 ? 193 VAL A CG2 1 
ATOM   1521 N N   . LEU A 1 192 ? -32.426 43.968  -5.516  1.00 40.80 ? 194 LEU A N   1 
ATOM   1522 C CA  . LEU A 1 192 ? -33.487 44.964  -5.592  1.00 41.72 ? 194 LEU A CA  1 
ATOM   1523 C C   . LEU A 1 192 ? -34.775 44.396  -5.010  1.00 41.63 ? 194 LEU A C   1 
ATOM   1524 O O   . LEU A 1 192 ? -35.238 43.329  -5.429  1.00 39.51 ? 194 LEU A O   1 
ATOM   1525 C CB  . LEU A 1 192 ? -33.714 45.390  -7.042  1.00 34.07 ? 194 LEU A CB  1 
ATOM   1526 C CG  . LEU A 1 192 ? -32.594 46.113  -7.797  1.00 38.20 ? 194 LEU A CG  1 
ATOM   1527 C CD1 . LEU A 1 192 ? -32.976 46.353  -9.249  1.00 31.75 ? 194 LEU A CD1 1 
ATOM   1528 C CD2 . LEU A 1 192 ? -32.228 47.430  -7.116  1.00 39.16 ? 194 LEU A CD2 1 
ATOM   1529 N N   . LEU A 1 193 ? -35.356 45.103  -4.035  1.00 41.95 ? 195 LEU A N   1 
ATOM   1530 C CA  . LEU A 1 193 ? -36.649 44.711  -3.494  1.00 39.27 ? 195 LEU A CA  1 
ATOM   1531 C C   . LEU A 1 193 ? -37.720 45.633  -4.051  1.00 41.43 ? 195 LEU A C   1 
ATOM   1532 O O   . LEU A 1 193 ? -37.732 46.829  -3.720  1.00 42.26 ? 195 LEU A O   1 
ATOM   1533 C CB  . LEU A 1 193 ? -36.648 44.749  -1.969  1.00 38.89 ? 195 LEU A CB  1 
ATOM   1534 C CG  . LEU A 1 193 ? -35.583 43.833  -1.368  1.00 41.38 ? 195 LEU A CG  1 
ATOM   1535 C CD1 . LEU A 1 193 ? -35.109 44.325  -0.006  1.00 46.96 ? 195 LEU A CD1 1 
ATOM   1536 C CD2 . LEU A 1 193 ? -36.089 42.404  -1.306  1.00 41.79 ? 195 LEU A CD2 1 
ATOM   1537 N N   . PRO A 1 194 ? -38.631 45.136  -4.876  1.00 41.80 ? 196 PRO A N   1 
ATOM   1538 C CA  . PRO A 1 194 ? -39.520 46.032  -5.615  1.00 41.63 ? 196 PRO A CA  1 
ATOM   1539 C C   . PRO A 1 194 ? -40.619 46.616  -4.746  1.00 38.87 ? 196 PRO A C   1 
ATOM   1540 O O   . PRO A 1 194 ? -41.029 46.040  -3.736  1.00 37.96 ? 196 PRO A O   1 
ATOM   1541 C CB  . PRO A 1 194 ? -40.114 45.113  -6.685  1.00 37.91 ? 196 PRO A CB  1 
ATOM   1542 C CG  . PRO A 1 194 ? -40.160 43.792  -5.993  1.00 34.47 ? 196 PRO A CG  1 
ATOM   1543 C CD  . PRO A 1 194 ? -38.854 43.729  -5.246  1.00 36.09 ? 196 PRO A CD  1 
ATOM   1544 N N   . ASP A 1 195 ? -41.090 47.783  -5.159  1.00 37.10 ? 197 ASP A N   1 
ATOM   1545 C CA  . ASP A 1 195 ? -42.433 48.196  -4.812  1.00 40.19 ? 197 ASP A CA  1 
ATOM   1546 C C   . ASP A 1 195 ? -43.426 47.250  -5.478  1.00 38.11 ? 197 ASP A C   1 
ATOM   1547 O O   . ASP A 1 195 ? -43.121 46.596  -6.479  1.00 35.37 ? 197 ASP A O   1 
ATOM   1548 C CB  . ASP A 1 195 ? -42.691 49.630  -5.275  1.00 41.15 ? 197 ASP A CB  1 
ATOM   1549 C CG  . ASP A 1 195 ? -42.004 50.663  -4.402  1.00 45.99 ? 197 ASP A CG  1 
ATOM   1550 O OD1 . ASP A 1 195 ? -41.932 51.833  -4.836  1.00 45.99 ? 197 ASP A OD1 1 
ATOM   1551 O OD2 . ASP A 1 195 ? -41.562 50.317  -3.282  1.00 45.29 ? 197 ASP A OD2 1 
ATOM   1552 N N   . ASN A 1 196 ? -44.626 47.187  -4.912  1.00 32.42 ? 198 ASN A N   1 
ATOM   1553 C CA  . ASN A 1 196 ? -45.665 46.335  -5.463  1.00 32.22 ? 198 ASN A CA  1 
ATOM   1554 C C   . ASN A 1 196 ? -45.907 46.676  -6.930  1.00 34.24 ? 198 ASN A C   1 
ATOM   1555 O O   . ASN A 1 196 ? -46.002 47.852  -7.297  1.00 29.94 ? 198 ASN A O   1 
ATOM   1556 C CB  . ASN A 1 196 ? -46.947 46.507  -4.652  1.00 30.15 ? 198 ASN A CB  1 
ATOM   1557 C CG  . ASN A 1 196 ? -46.814 45.978  -3.226  1.00 38.89 ? 198 ASN A CG  1 
ATOM   1558 O OD1 . ASN A 1 196 ? -45.766 45.457  -2.837  1.00 35.25 ? 198 ASN A OD1 1 
ATOM   1559 N ND2 . ASN A 1 196 ? -47.885 46.104  -2.446  1.00 39.31 ? 198 ASN A ND2 1 
ATOM   1560 N N   . HIS A 1 197 ? -45.969 45.646  -7.779  1.00 27.55 ? 199 HIS A N   1 
ATOM   1561 C CA  . HIS A 1 197 ? -46.245 45.854  -9.198  1.00 25.24 ? 199 HIS A CA  1 
ATOM   1562 C C   . HIS A 1 197 ? -46.842 44.577  -9.784  1.00 25.12 ? 199 HIS A C   1 
ATOM   1563 O O   . HIS A 1 197 ? -47.057 43.586  -9.081  1.00 21.42 ? 199 HIS A O   1 
ATOM   1564 C CB  . HIS A 1 197 ? -44.989 46.271  -9.958  1.00 26.59 ? 199 HIS A CB  1 
ATOM   1565 C CG  . HIS A 1 197 ? -43.950 45.201  -10.044 1.00 24.86 ? 199 HIS A CG  1 
ATOM   1566 N ND1 . HIS A 1 197 ? -43.173 44.830  -8.967  1.00 28.66 ? 199 HIS A ND1 1 
ATOM   1567 C CD2 . HIS A 1 197 ? -43.535 44.443  -11.086 1.00 26.59 ? 199 HIS A CD2 1 
ATOM   1568 C CE1 . HIS A 1 197 ? -42.339 43.875  -9.338  1.00 30.94 ? 199 HIS A CE1 1 
ATOM   1569 N NE2 . HIS A 1 197 ? -42.535 43.624  -10.620 1.00 27.34 ? 199 HIS A NE2 1 
ATOM   1570 N N   . TYR A 1 198 ? -47.114 44.611  -11.087 1.00 20.41 ? 200 TYR A N   1 
ATOM   1571 C CA  . TYR A 1 198 ? -47.757 43.493  -11.764 1.00 20.80 ? 200 TYR A CA  1 
ATOM   1572 C C   . TYR A 1 198 ? -46.828 42.897  -12.813 1.00 19.83 ? 200 TYR A C   1 
ATOM   1573 O O   . TYR A 1 198 ? -46.014 43.602  -13.420 1.00 20.34 ? 200 TYR A O   1 
ATOM   1574 C CB  . TYR A 1 198 ? -49.070 43.915  -12.447 1.00 21.57 ? 200 TYR A CB  1 
ATOM   1575 C CG  . TYR A 1 198 ? -50.252 44.114  -11.513 1.00 26.02 ? 200 TYR A CG  1 
ATOM   1576 C CD1 . TYR A 1 198 ? -51.043 43.038  -11.119 1.00 25.85 ? 200 TYR A CD1 1 
ATOM   1577 C CD2 . TYR A 1 198 ? -50.613 45.383  -11.075 1.00 30.10 ? 200 TYR A CD2 1 
ATOM   1578 C CE1 . TYR A 1 198 ? -52.133 43.214  -10.280 1.00 30.21 ? 200 TYR A CE1 1 
ATOM   1579 C CE2 . TYR A 1 198 ? -51.707 45.569  -10.241 1.00 32.77 ? 200 TYR A CE2 1 
ATOM   1580 C CZ  . TYR A 1 198 ? -52.465 44.481  -9.847  1.00 30.79 ? 200 TYR A CZ  1 
ATOM   1581 O OH  . TYR A 1 198 ? -53.554 44.664  -9.010  1.00 35.33 ? 200 TYR A OH  1 
ATOM   1582 N N   . LEU A 1 199 ? -46.946 41.582  -12.999 1.00 17.22 ? 201 LEU A N   1 
ATOM   1583 C CA  . LEU A 1 199 ? -46.468 40.894  -14.192 1.00 17.97 ? 201 LEU A CA  1 
ATOM   1584 C C   . LEU A 1 199 ? -47.698 40.477  -14.982 1.00 17.28 ? 201 LEU A C   1 
ATOM   1585 O O   . LEU A 1 199 ? -48.618 39.870  -14.417 1.00 19.93 ? 201 LEU A O   1 
ATOM   1586 C CB  . LEU A 1 199 ? -45.635 39.650  -13.851 1.00 16.46 ? 201 LEU A CB  1 
ATOM   1587 C CG  . LEU A 1 199 ? -44.342 39.937  -13.085 1.00 17.53 ? 201 LEU A CG  1 
ATOM   1588 C CD1 . LEU A 1 199 ? -43.534 38.642  -12.840 1.00 17.16 ? 201 LEU A CD1 1 
ATOM   1589 C CD2 . LEU A 1 199 ? -43.534 41.018  -13.771 1.00 19.37 ? 201 LEU A CD2 1 
ATOM   1590 N N   . PHE A 1 200 ? -47.725 40.813  -16.265 1.00 13.88 ? 202 PHE A N   1 
ATOM   1591 C CA  . PHE A 1 200 ? -48.811 40.426  -17.156 1.00 18.00 ? 202 PHE A CA  1 
ATOM   1592 C C   . PHE A 1 200 ? -48.274 39.484  -18.227 1.00 16.60 ? 202 PHE A C   1 
ATOM   1593 O O   . PHE A 1 200 ? -47.275 39.792  -18.881 1.00 17.53 ? 202 PHE A O   1 
ATOM   1594 C CB  . PHE A 1 200 ? -49.446 41.658  -17.799 1.00 17.89 ? 202 PHE A CB  1 
ATOM   1595 C CG  . PHE A 1 200 ? -50.124 42.586  -16.805 1.00 19.01 ? 202 PHE A CG  1 
ATOM   1596 C CD1 . PHE A 1 200 ? -49.841 43.945  -16.792 1.00 26.36 ? 202 PHE A CD1 1 
ATOM   1597 C CD2 . PHE A 1 200 ? -51.036 42.093  -15.892 1.00 23.56 ? 202 PHE A CD2 1 
ATOM   1598 C CE1 . PHE A 1 200 ? -50.481 44.801  -15.892 1.00 21.96 ? 202 PHE A CE1 1 
ATOM   1599 C CE2 . PHE A 1 200 ? -51.671 42.942  -14.985 1.00 25.21 ? 202 PHE A CE2 1 
ATOM   1600 C CZ  . PHE A 1 200 ? -51.387 44.294  -14.991 1.00 22.34 ? 202 PHE A CZ  1 
ATOM   1601 N N   . THR A 1 201 ? -48.947 38.348  -18.411 1.00 15.28 ? 203 THR A N   1 
ATOM   1602 C CA  . THR A 1 201 ? -48.418 37.245  -19.205 1.00 16.09 ? 203 THR A CA  1 
ATOM   1603 C C   . THR A 1 201 ? -49.448 36.814  -20.235 1.00 15.89 ? 203 THR A C   1 
ATOM   1604 O O   . THR A 1 201 ? -50.643 36.758  -19.930 1.00 16.09 ? 203 THR A O   1 
ATOM   1605 C CB  . THR A 1 201 ? -48.080 36.052  -18.305 1.00 15.16 ? 203 THR A CB  1 
ATOM   1606 O OG1 . THR A 1 201 ? -47.083 36.452  -17.355 1.00 15.66 ? 203 THR A OG1 1 
ATOM   1607 C CG2 . THR A 1 201 ? -47.536 34.873  -19.142 1.00 16.30 ? 203 THR A CG2 1 
ATOM   1608 N N   . THR A 1 202 ? -48.987 36.481  -21.446 1.00 13.43 ? 204 THR A N   1 
ATOM   1609 C CA  . THR A 1 202 ? -49.850 35.896  -22.473 1.00 11.94 ? 204 THR A CA  1 
ATOM   1610 C C   . THR A 1 202 ? -49.184 34.627  -22.971 1.00 12.40 ? 204 THR A C   1 
ATOM   1611 O O   . THR A 1 202 ? -48.102 34.697  -23.560 1.00 15.65 ? 204 THR A O   1 
ATOM   1612 C CB  . THR A 1 202 ? -50.074 36.853  -23.649 1.00 13.51 ? 204 THR A CB  1 
ATOM   1613 O OG1 . THR A 1 202 ? -50.646 38.073  -23.165 1.00 14.35 ? 204 THR A OG1 1 
ATOM   1614 C CG2 . THR A 1 202 ? -50.994 36.218  -24.688 1.00 13.73 ? 204 THR A CG2 1 
ATOM   1615 N N   . SER A 1 203 ? -49.836 33.484  -22.764 1.00 13.38 ? 205 SER A N   1 
ATOM   1616 C CA  . SER A 1 203 ? -49.265 32.174  -23.067 1.00 14.66 ? 205 SER A CA  1 
ATOM   1617 C C   . SER A 1 203 ? -50.058 31.515  -24.182 1.00 17.83 ? 205 SER A C   1 
ATOM   1618 O O   . SER A 1 203 ? -51.291 31.517  -24.150 1.00 18.89 ? 205 SER A O   1 
ATOM   1619 C CB  . SER A 1 203 ? -49.281 31.252  -21.837 1.00 13.67 ? 205 SER A CB  1 
ATOM   1620 O OG  . SER A 1 203 ? -48.702 31.880  -20.719 1.00 16.58 ? 205 SER A OG  1 
ATOM   1621 N N   . THR A 1 204 ? -49.359 30.917  -25.140 1.00 15.22 ? 206 THR A N   1 
ATOM   1622 C CA  . THR A 1 204 ? -49.980 30.113  -26.189 1.00 13.81 ? 206 THR A CA  1 
ATOM   1623 C C   . THR A 1 204 ? -49.321 28.746  -26.211 1.00 14.87 ? 206 THR A C   1 
ATOM   1624 O O   . THR A 1 204 ? -48.092 28.654  -26.323 1.00 14.19 ? 206 THR A O   1 
ATOM   1625 C CB  . THR A 1 204 ? -49.848 30.776  -27.565 1.00 18.10 ? 206 THR A CB  1 
ATOM   1626 O OG1 . THR A 1 204 ? -50.310 32.125  -27.489 1.00 17.91 ? 206 THR A OG1 1 
ATOM   1627 C CG2 . THR A 1 204 ? -50.642 29.994  -28.639 1.00 18.51 ? 206 THR A CG2 1 
ATOM   1628 N N   . LEU A 1 205 ? -50.140 27.693  -26.120 1.00 13.90 ? 207 LEU A N   1 
ATOM   1629 C CA  . LEU A 1 205 ? -49.684 26.308  -26.126 1.00 17.00 ? 207 LEU A CA  1 
ATOM   1630 C C   . LEU A 1 205 ? -49.965 25.692  -27.493 1.00 16.92 ? 207 LEU A C   1 
ATOM   1631 O O   . LEU A 1 205 ? -51.036 25.902  -28.062 1.00 18.03 ? 207 LEU A O   1 
ATOM   1632 C CB  . LEU A 1 205 ? -50.407 25.492  -25.051 1.00 15.62 ? 207 LEU A CB  1 
ATOM   1633 C CG  . LEU A 1 205 ? -50.620 25.999  -23.622 1.00 21.08 ? 207 LEU A CG  1 
ATOM   1634 C CD1 . LEU A 1 205 ? -51.069 24.840  -22.721 1.00 18.50 ? 207 LEU A CD1 1 
ATOM   1635 C CD2 . LEU A 1 205 ? -49.378 26.645  -23.074 1.00 21.48 ? 207 LEU A CD2 1 
ATOM   1636 N N   . SER A 1 206 ? -49.028 24.909  -28.012 1.00 17.28 ? 208 SER A N   1 
ATOM   1637 C CA  . SER A 1 206 ? -49.277 24.255  -29.289 1.00 17.21 ? 208 SER A CA  1 
ATOM   1638 C C   . SER A 1 206 ? -48.532 22.927  -29.324 1.00 19.16 ? 208 SER A C   1 
ATOM   1639 O O   . SER A 1 206 ? -47.896 22.523  -28.348 1.00 16.39 ? 208 SER A O   1 
ATOM   1640 C CB  . SER A 1 206 ? -48.860 25.152  -30.454 1.00 18.41 ? 208 SER A CB  1 
ATOM   1641 O OG  . SER A 1 206 ? -47.519 25.555  -30.294 1.00 21.14 ? 208 SER A OG  1 
ATOM   1642 N N   . LYS A 1 207 ? -48.624 22.239  -30.459 1.00 18.43 ? 209 LYS A N   1 
ATOM   1643 C CA  . LYS A 1 207 ? -47.920 20.978  -30.653 1.00 18.72 ? 209 LYS A CA  1 
ATOM   1644 C C   . LYS A 1 207 ? -47.002 21.093  -31.858 1.00 23.34 ? 209 LYS A C   1 
ATOM   1645 O O   . LYS A 1 207 ? -47.232 21.898  -32.767 1.00 22.25 ? 209 LYS A O   1 
ATOM   1646 C CB  . LYS A 1 207 ? -48.891 19.804  -30.847 1.00 20.75 ? 209 LYS A CB  1 
ATOM   1647 C CG  . LYS A 1 207 ? -49.828 19.553  -29.652 1.00 21.06 ? 209 LYS A CG  1 
ATOM   1648 C CD  . LYS A 1 207 ? -49.112 18.957  -28.433 1.00 16.56 ? 209 LYS A CD  1 
ATOM   1649 C CE  . LYS A 1 207 ? -50.108 18.509  -27.373 1.00 20.26 ? 209 LYS A CE  1 
ATOM   1650 N NZ  . LYS A 1 207 ? -49.456 18.040  -26.090 1.00 16.64 ? 209 LYS A NZ  1 
ATOM   1651 N N   . ASP A 1 208 ? -45.951 20.286  -31.844 1.00 20.82 ? 210 ASP A N   1 
ATOM   1652 C CA  . ASP A 1 208 ? -45.011 20.189  -32.945 1.00 23.66 ? 210 ASP A CA  1 
ATOM   1653 C C   . ASP A 1 208 ? -45.444 18.988  -33.775 1.00 24.18 ? 210 ASP A C   1 
ATOM   1654 O O   . ASP A 1 208 ? -45.437 17.862  -33.257 1.00 21.15 ? 210 ASP A O   1 
ATOM   1655 C CB  . ASP A 1 208 ? -43.591 20.012  -32.392 1.00 21.40 ? 210 ASP A CB  1 
ATOM   1656 C CG  . ASP A 1 208 ? -42.556 19.671  -33.448 1.00 27.23 ? 210 ASP A CG  1 
ATOM   1657 O OD1 . ASP A 1 208 ? -42.888 19.527  -34.641 1.00 29.68 ? 210 ASP A OD1 1 
ATOM   1658 O OD2 . ASP A 1 208 ? -41.371 19.578  -33.060 1.00 25.73 ? 210 ASP A OD2 1 
ATOM   1659 N N   . PRO A 1 209 ? -45.866 19.175  -35.034 1.00 27.80 ? 211 PRO A N   1 
ATOM   1660 C CA  . PRO A 1 209 ? -46.448 18.053  -35.800 1.00 28.42 ? 211 PRO A CA  1 
ATOM   1661 C C   . PRO A 1 209 ? -45.482 16.904  -36.011 1.00 27.27 ? 211 PRO A C   1 
ATOM   1662 O O   . PRO A 1 209 ? -45.925 15.770  -36.243 1.00 31.43 ? 211 PRO A O   1 
ATOM   1663 C CB  . PRO A 1 209 ? -46.832 18.680  -37.151 1.00 30.94 ? 211 PRO A CB  1 
ATOM   1664 C CG  . PRO A 1 209 ? -46.317 20.075  -37.156 1.00 28.28 ? 211 PRO A CG  1 
ATOM   1665 C CD  . PRO A 1 209 ? -45.835 20.444  -35.783 1.00 27.15 ? 211 PRO A CD  1 
ATOM   1666 N N   . ASN A 1 210 ? -44.182 17.170  -35.948 1.00 27.07 ? 212 ASN A N   1 
ATOM   1667 C CA  . ASN A 1 210 ? -43.148 16.180  -36.179 1.00 28.96 ? 212 ASN A CA  1 
ATOM   1668 C C   . ASN A 1 210 ? -42.599 15.569  -34.894 1.00 31.36 ? 212 ASN A C   1 
ATOM   1669 O O   . ASN A 1 210 ? -41.645 14.786  -34.959 1.00 32.60 ? 212 ASN A O   1 
ATOM   1670 C CB  . ASN A 1 210 ? -42.016 16.818  -36.984 1.00 35.20 ? 212 ASN A CB  1 
ATOM   1671 C CG  . ASN A 1 210 ? -42.445 17.161  -38.405 1.00 38.16 ? 212 ASN A CG  1 
ATOM   1672 O OD1 . ASN A 1 210 ? -43.274 16.472  -39.000 1.00 37.30 ? 212 ASN A OD1 1 
ATOM   1673 N ND2 . ASN A 1 210 ? -41.920 18.253  -38.930 1.00 37.60 ? 212 ASN A ND2 1 
ATOM   1674 N N   . GLU A 1 211 ? -43.174 15.897  -33.736 1.00 25.18 ? 213 GLU A N   1 
ATOM   1675 C CA  . GLU A 1 211 ? -42.740 15.352  -32.456 1.00 22.49 ? 213 GLU A CA  1 
ATOM   1676 C C   . GLU A 1 211 ? -43.657 14.207  -32.044 1.00 25.15 ? 213 GLU A C   1 
ATOM   1677 O O   . GLU A 1 211 ? -44.848 14.420  -31.795 1.00 26.91 ? 213 GLU A O   1 
ATOM   1678 C CB  . GLU A 1 211 ? -42.741 16.430  -31.373 1.00 24.20 ? 213 GLU A CB  1 
ATOM   1679 C CG  . GLU A 1 211 ? -42.333 15.898  -30.027 1.00 22.65 ? 213 GLU A CG  1 
ATOM   1680 C CD  . GLU A 1 211 ? -40.931 15.316  -30.048 1.00 25.22 ? 213 GLU A CD  1 
ATOM   1681 O OE1 . GLU A 1 211 ? -39.974 16.087  -30.254 1.00 21.66 ? 213 GLU A OE1 1 
ATOM   1682 O OE2 . GLU A 1 211 ? -40.793 14.089  -29.888 1.00 25.11 ? 213 GLU A OE2 1 
ATOM   1683 N N   . LYS A 1 212 ? -43.093 13.003  -31.929 1.00 23.03 ? 214 LYS A N   1 
ATOM   1684 C CA  . LYS A 1 212 ? -43.870 11.861  -31.463 1.00 23.87 ? 214 LYS A CA  1 
ATOM   1685 C C   . LYS A 1 212 ? -43.920 11.760  -29.944 1.00 23.86 ? 214 LYS A C   1 
ATOM   1686 O O   . LYS A 1 212 ? -44.795 11.078  -29.411 1.00 23.52 ? 214 LYS A O   1 
ATOM   1687 C CB  . LYS A 1 212 ? -43.319 10.544  -32.039 1.00 30.40 ? 214 LYS A CB  1 
ATOM   1688 C CG  . LYS A 1 212 ? -41.964 10.054  -31.473 1.00 31.02 ? 214 LYS A CG  1 
ATOM   1689 C CD  . LYS A 1 212 ? -40.813 11.040  -31.665 1.00 35.82 ? 214 LYS A CD  1 
ATOM   1690 C CE  . LYS A 1 212 ? -39.445 10.379  -31.526 1.00 39.12 ? 214 LYS A CE  1 
ATOM   1691 N NZ  . LYS A 1 212 ? -38.413 11.415  -31.170 1.00 43.42 ? 214 LYS A NZ  1 
ATOM   1692 N N   . ARG A 1 213 ? -43.012 12.411  -29.229 1.00 20.67 ? 215 ARG A N   1 
ATOM   1693 C CA  . ARG A 1 213 ? -43.080 12.265  -27.790 1.00 23.23 ? 215 ARG A CA  1 
ATOM   1694 C C   . ARG A 1 213 ? -44.124 13.215  -27.208 1.00 19.20 ? 215 ARG A C   1 
ATOM   1695 O O   . ARG A 1 213 ? -44.517 14.201  -27.833 1.00 20.32 ? 215 ARG A O   1 
ATOM   1696 C CB  . ARG A 1 213 ? -41.709 12.511  -27.161 1.00 21.57 ? 215 ARG A CB  1 
ATOM   1697 C CG  . ARG A 1 213 ? -40.662 11.508  -27.632 1.00 26.21 ? 215 ARG A CG  1 
ATOM   1698 C CD  . ARG A 1 213 ? -39.307 11.794  -27.063 1.00 28.54 ? 215 ARG A CD  1 
ATOM   1699 N NE  . ARG A 1 213 ? -38.600 12.860  -27.753 1.00 35.51 ? 215 ARG A NE  1 
ATOM   1700 C CZ  . ARG A 1 213 ? -37.383 13.255  -27.409 1.00 37.73 ? 215 ARG A CZ  1 
ATOM   1701 N NH1 . ARG A 1 213 ? -36.746 12.698  -26.383 1.00 35.60 ? 215 ARG A NH1 1 
ATOM   1702 N NH2 . ARG A 1 213 ? -36.792 14.225  -28.109 1.00 34.01 ? 215 ARG A NH2 1 
ATOM   1703 N N   . ASP A 1 214 ? -44.591 12.875  -26.008 1.00 18.48 ? 216 ASP A N   1 
ATOM   1704 C CA  . ASP A 1 214 ? -45.484 13.757  -25.261 1.00 18.44 ? 216 ASP A CA  1 
ATOM   1705 C C   . ASP A 1 214 ? -44.774 15.074  -24.989 1.00 17.53 ? 216 ASP A C   1 
ATOM   1706 O O   . ASP A 1 214 ? -43.663 15.090  -24.449 1.00 15.50 ? 216 ASP A O   1 
ATOM   1707 C CB  . ASP A 1 214 ? -45.905 13.092  -23.954 1.00 16.80 ? 216 ASP A CB  1 
ATOM   1708 C CG  . ASP A 1 214 ? -47.210 13.640  -23.399 1.00 20.57 ? 216 ASP A CG  1 
ATOM   1709 O OD1 . ASP A 1 214 ? -47.759 14.602  -23.976 1.00 18.36 ? 216 ASP A OD1 1 
ATOM   1710 O OD2 . ASP A 1 214 ? -47.665 13.121  -22.356 1.00 18.32 ? 216 ASP A OD2 1 
ATOM   1711 N N   . HIS A 1 215 ? -45.406 16.183  -25.371 1.00 18.40 ? 217 HIS A N   1 
ATOM   1712 C CA  . HIS A 1 215 ? -44.689 17.452  -25.401 1.00 14.35 ? 217 HIS A CA  1 
ATOM   1713 C C   . HIS A 1 215 ? -45.649 18.640  -25.379 1.00 16.68 ? 217 HIS A C   1 
ATOM   1714 O O   . HIS A 1 215 ? -46.865 18.501  -25.516 1.00 17.97 ? 217 HIS A O   1 
ATOM   1715 C CB  . HIS A 1 215 ? -43.780 17.526  -26.630 1.00 16.46 ? 217 HIS A CB  1 
ATOM   1716 C CG  . HIS A 1 215 ? -44.535 17.778  -27.893 1.00 17.29 ? 217 HIS A CG  1 
ATOM   1717 N ND1 . HIS A 1 215 ? -45.220 16.778  -28.546 1.00 17.24 ? 217 HIS A ND1 1 
ATOM   1718 C CD2 . HIS A 1 215 ? -44.774 18.918  -28.587 1.00 15.07 ? 217 HIS A CD2 1 
ATOM   1719 C CE1 . HIS A 1 215 ? -45.815 17.281  -29.616 1.00 19.07 ? 217 HIS A CE1 1 
ATOM   1720 N NE2 . HIS A 1 215 ? -45.564 18.578  -29.660 1.00 16.89 ? 217 HIS A NE2 1 
ATOM   1721 N N   . MET A 1 216 ? -45.048 19.816  -25.197 1.00 16.43 ? 218 MET A N   1 
ATOM   1722 C CA  . MET A 1 216 ? -45.701 21.117  -25.112 1.00 14.71 ? 218 MET A CA  1 
ATOM   1723 C C   . MET A 1 216 ? -44.803 22.134  -25.775 1.00 14.02 ? 218 MET A C   1 
ATOM   1724 O O   . MET A 1 216 ? -43.690 22.339  -25.293 1.00 15.14 ? 218 MET A O   1 
ATOM   1725 C CB  . MET A 1 216 ? -45.903 21.561  -23.662 1.00 15.14 ? 218 MET A CB  1 
ATOM   1726 C CG  . MET A 1 216 ? -46.563 22.939  -23.576 1.00 13.95 ? 218 MET A CG  1 
ATOM   1727 S SD  . MET A 1 216 ? -47.390 23.350  -22.019 1.00 15.13 ? 218 MET A SD  1 
ATOM   1728 C CE  . MET A 1 216 ? -45.910 23.561  -20.977 1.00 11.92 ? 218 MET A CE  1 
ATOM   1729 N N   . VAL A 1 217 ? -45.287 22.812  -26.815 1.00 15.36 ? 219 VAL A N   1 
ATOM   1730 C CA  . VAL A 1 217 ? -44.618 24.003  -27.327 1.00 13.49 ? 219 VAL A CA  1 
ATOM   1731 C C   . VAL A 1 217 ? -45.296 25.203  -26.679 1.00 15.32 ? 219 VAL A C   1 
ATOM   1732 O O   . VAL A 1 217 ? -46.531 25.258  -26.604 1.00 14.17 ? 219 VAL A O   1 
ATOM   1733 C CB  . VAL A 1 217 ? -44.700 24.078  -28.863 1.00 17.83 ? 219 VAL A CB  1 
ATOM   1734 C CG1 . VAL A 1 217 ? -44.093 25.377  -29.378 1.00 16.48 ? 219 VAL A CG1 1 
ATOM   1735 C CG2 . VAL A 1 217 ? -44.006 22.864  -29.512 1.00 17.17 ? 219 VAL A CG2 1 
ATOM   1736 N N   . LEU A 1 218 ? -44.500 26.147  -26.173 1.00 14.32 ? 220 LEU A N   1 
ATOM   1737 C CA  . LEU A 1 218 ? -45.044 27.235  -25.370 1.00 15.47 ? 220 LEU A CA  1 
ATOM   1738 C C   . LEU A 1 218 ? -44.465 28.546  -25.876 1.00 17.15 ? 220 LEU A C   1 
ATOM   1739 O O   . LEU A 1 218 ? -43.246 28.677  -26.022 1.00 17.46 ? 220 LEU A O   1 
ATOM   1740 C CB  . LEU A 1 218 ? -44.718 27.047  -23.872 1.00 15.75 ? 220 LEU A CB  1 
ATOM   1741 C CG  . LEU A 1 218 ? -44.855 28.269  -22.951 1.00 19.22 ? 220 LEU A CG  1 
ATOM   1742 C CD1 . LEU A 1 218 ? -46.315 28.646  -22.892 1.00 19.83 ? 220 LEU A CD1 1 
ATOM   1743 C CD2 . LEU A 1 218 ? -44.382 27.947  -21.539 1.00 22.50 ? 220 LEU A CD2 1 
ATOM   1744 N N   . LEU A 1 219 ? -45.331 29.513  -26.155 1.00 13.75 ? 221 LEU A N   1 
ATOM   1745 C CA  . LEU A 1 219 ? -44.882 30.831  -26.580 1.00 14.69 ? 221 LEU A CA  1 
ATOM   1746 C C   . LEU A 1 219 ? -45.519 31.840  -25.646 1.00 15.71 ? 221 LEU A C   1 
ATOM   1747 O O   . LEU A 1 219 ? -46.730 31.784  -25.412 1.00 15.94 ? 221 LEU A O   1 
ATOM   1748 C CB  . LEU A 1 219 ? -45.255 31.123  -28.039 1.00 17.94 ? 221 LEU A CB  1 
ATOM   1749 C CG  . LEU A 1 219 ? -45.086 32.600  -28.413 1.00 18.98 ? 221 LEU A CG  1 
ATOM   1750 C CD1 . LEU A 1 219 ? -43.622 32.940  -28.584 1.00 19.67 ? 221 LEU A CD1 1 
ATOM   1751 C CD2 . LEU A 1 219 ? -45.832 32.930  -29.701 1.00 18.35 ? 221 LEU A CD2 1 
ATOM   1752 N N   . GLU A 1 220 ? -44.708 32.748  -25.110 1.00 15.81 ? 222 GLU A N   1 
ATOM   1753 C CA  . GLU A 1 220 ? -45.114 33.576  -23.986 1.00 16.71 ? 222 GLU A CA  1 
ATOM   1754 C C   . GLU A 1 220 ? -44.603 34.999  -24.153 1.00 16.11 ? 222 GLU A C   1 
ATOM   1755 O O   . GLU A 1 220 ? -43.465 35.213  -24.569 1.00 19.41 ? 222 GLU A O   1 
ATOM   1756 C CB  . GLU A 1 220 ? -44.595 32.917  -22.702 1.00 20.68 ? 222 GLU A CB  1 
ATOM   1757 C CG  . GLU A 1 220 ? -45.363 33.169  -21.463 1.00 23.17 ? 222 GLU A CG  1 
ATOM   1758 C CD  . GLU A 1 220 ? -44.968 32.191  -20.358 1.00 25.11 ? 222 GLU A CD  1 
ATOM   1759 O OE1 . GLU A 1 220 ? -45.597 31.122  -20.255 1.00 29.89 ? 222 GLU A OE1 1 
ATOM   1760 O OE2 . GLU A 1 220 ? -43.974 32.446  -19.663 1.00 30.53 ? 222 GLU A OE2 1 
ATOM   1761 N N   . PHE A 1 221 ? -45.466 35.971  -23.865 1.00 14.40 ? 223 PHE A N   1 
ATOM   1762 C CA  . PHE A 1 221 ? -45.101 37.377  -23.842 1.00 13.80 ? 223 PHE A CA  1 
ATOM   1763 C C   . PHE A 1 221 ? -45.423 37.917  -22.459 1.00 15.66 ? 223 PHE A C   1 
ATOM   1764 O O   . PHE A 1 221 ? -46.467 37.590  -21.894 1.00 15.28 ? 223 PHE A O   1 
ATOM   1765 C CB  . PHE A 1 221 ? -45.864 38.157  -24.927 1.00 13.60 ? 223 PHE A CB  1 
ATOM   1766 C CG  . PHE A 1 221 ? -45.655 37.611  -26.297 1.00 14.42 ? 223 PHE A CG  1 
ATOM   1767 C CD1 . PHE A 1 221 ? -44.602 38.046  -27.082 1.00 15.49 ? 223 PHE A CD1 1 
ATOM   1768 C CD2 . PHE A 1 221 ? -46.510 36.638  -26.797 1.00 15.61 ? 223 PHE A CD2 1 
ATOM   1769 C CE1 . PHE A 1 221 ? -44.398 37.515  -28.344 1.00 18.21 ? 223 PHE A CE1 1 
ATOM   1770 C CE2 . PHE A 1 221 ? -46.324 36.118  -28.056 1.00 17.48 ? 223 PHE A CE2 1 
ATOM   1771 C CZ  . PHE A 1 221 ? -45.261 36.547  -28.830 1.00 16.41 ? 223 PHE A CZ  1 
ATOM   1772 N N   . VAL A 1 222 ? -44.522 38.708  -21.886 1.00 16.64 ? 224 VAL A N   1 
ATOM   1773 C CA  . VAL A 1 222 ? -44.697 39.112  -20.490 1.00 16.84 ? 224 VAL A CA  1 
ATOM   1774 C C   . VAL A 1 222 ? -44.085 40.492  -20.276 1.00 19.18 ? 224 VAL A C   1 
ATOM   1775 O O   . VAL A 1 222 ? -42.974 40.773  -20.731 1.00 16.34 ? 224 VAL A O   1 
ATOM   1776 C CB  . VAL A 1 222 ? -44.089 38.077  -19.518 1.00 22.12 ? 224 VAL A CB  1 
ATOM   1777 C CG1 . VAL A 1 222 ? -42.712 37.682  -19.961 1.00 23.48 ? 224 VAL A CG1 1 
ATOM   1778 C CG2 . VAL A 1 222 ? -44.071 38.609  -18.078 1.00 21.34 ? 224 VAL A CG2 1 
ATOM   1779 N N   . THR A 1 223 ? -44.817 41.368  -19.593 1.00 18.13 ? 225 THR A N   1 
ATOM   1780 C CA  . THR A 1 223 ? -44.264 42.662  -19.242 1.00 14.80 ? 225 THR A CA  1 
ATOM   1781 C C   . THR A 1 223 ? -44.573 42.955  -17.784 1.00 17.14 ? 225 THR A C   1 
ATOM   1782 O O   . THR A 1 223 ? -45.541 42.440  -17.221 1.00 18.22 ? 225 THR A O   1 
ATOM   1783 C CB  . THR A 1 223 ? -44.839 43.783  -20.119 1.00 23.48 ? 225 THR A CB  1 
ATOM   1784 O OG1 . THR A 1 223 ? -44.417 45.041  -19.592 1.00 26.33 ? 225 THR A OG1 1 
ATOM   1785 C CG2 . THR A 1 223 ? -46.357 43.742  -20.052 1.00 20.96 ? 225 THR A CG2 1 
ATOM   1786 N N   . ALA A 1 224 ? -43.727 43.772  -17.169 1.00 20.97 ? 226 ALA A N   1 
ATOM   1787 C CA  . ALA A 1 224 ? -44.006 44.282  -15.838 1.00 23.18 ? 226 ALA A CA  1 
ATOM   1788 C C   . ALA A 1 224 ? -44.747 45.605  -15.967 1.00 24.37 ? 226 ALA A C   1 
ATOM   1789 O O   . ALA A 1 224 ? -44.610 46.309  -16.969 1.00 26.22 ? 226 ALA A O   1 
ATOM   1790 C CB  . ALA A 1 224 ? -42.712 44.468  -15.042 1.00 26.66 ? 226 ALA A CB  1 
ATOM   1791 N N   . ALA A 1 225 ? -45.557 45.927  -14.962 1.00 27.39 ? 227 ALA A N   1 
ATOM   1792 C CA  . ALA A 1 225 ? -46.312 47.173  -14.985 1.00 27.74 ? 227 ALA A CA  1 
ATOM   1793 C C   . ALA A 1 225 ? -46.521 47.663  -13.560 1.00 32.33 ? 227 ALA A C   1 
ATOM   1794 O O   . ALA A 1 225 ? -46.591 46.868  -12.620 1.00 29.09 ? 227 ALA A O   1 
ATOM   1795 C CB  . ALA A 1 225 ? -47.664 47.006  -15.687 1.00 26.49 ? 227 ALA A CB  1 
ATOM   1796 N N   . GLY A 1 226 ? -46.642 48.984  -13.412 1.00 38.20 ? 228 GLY A N   1 
ATOM   1797 C CA  . GLY A 1 226 ? -46.787 49.596  -12.108 1.00 40.21 ? 228 GLY A CA  1 
ATOM   1798 C C   . GLY A 1 226 ? -48.230 49.707  -11.647 1.00 44.75 ? 228 GLY A C   1 
ATOM   1799 O O   . GLY A 1 226 ? -49.170 49.321  -12.341 1.00 45.22 ? 228 GLY A O   1 
ATOM   1800 N N   . ILE A 1 227 ? -48.382 50.252  -10.433 1.00 46.87 ? 229 ILE A N   1 
ATOM   1801 C CA  . ILE A 1 227 ? -49.673 50.492  -9.784  1.00 47.16 ? 229 ILE A CA  1 
ATOM   1802 C C   . ILE A 1 227 ? -50.345 49.166  -9.442  1.00 49.78 ? 229 ILE A C   1 
ATOM   1803 O O   . ILE A 1 227 ? -49.794 48.357  -8.688  1.00 48.06 ? 229 ILE A O   1 
ATOM   1804 C CB  . ILE A 1 227 ? -50.595 51.382  -10.655 1.00 45.82 ? 229 ILE A CB  1 
ATOM   1805 C CG1 . ILE A 1 227 ? -50.304 52.860  -10.395 1.00 48.98 ? 229 ILE A CG1 1 
ATOM   1806 C CG2 . ILE A 1 227 ? -52.060 51.083  -10.373 1.00 46.87 ? 229 ILE A CG2 1 
ATOM   1807 C CD1 . ILE A 1 227 ? -51.151 53.807  -11.231 1.00 46.73 ? 229 ILE A CD1 1 
ATOM   1808 N N   . LYS B 1 3   ? -39.987 -9.365  -8.649  1.00 41.24 ? 3   LYS B N   1 
ATOM   1809 C CA  . LYS B 1 3   ? -38.638 -8.846  -8.655  1.00 36.76 ? 3   LYS B CA  1 
ATOM   1810 C C   . LYS B 1 3   ? -38.469 -7.582  -9.496  1.00 38.07 ? 3   LYS B C   1 
ATOM   1811 O O   . LYS B 1 3   ? -39.116 -7.389  -10.532 1.00 35.50 ? 3   LYS B O   1 
ATOM   1812 C CB  . LYS B 1 3   ? -37.668 -9.929  -9.136  1.00 37.11 ? 3   LYS B CB  1 
ATOM   1813 C CG  . LYS B 1 3   ? -37.395 -11.012 -8.108  1.00 37.67 ? 3   LYS B CG  1 
ATOM   1814 C CD  . LYS B 1 3   ? -36.349 -11.998 -8.595  1.00 40.38 ? 3   LYS B CD  1 
ATOM   1815 C CE  . LYS B 1 3   ? -36.950 -12.883 -9.674  1.00 38.74 ? 3   LYS B CE  1 
ATOM   1816 N NZ  . LYS B 1 3   ? -36.042 -13.994 -10.095 1.00 43.81 ? 3   LYS B NZ  1 
ATOM   1817 N N   . GLY B 1 4   ? -37.588 -6.702  -9.020  1.00 32.19 ? 4   GLY B N   1 
ATOM   1818 C CA  . GLY B 1 4   ? -37.045 -5.702  -9.911  1.00 28.97 ? 4   GLY B CA  1 
ATOM   1819 C C   . GLY B 1 4   ? -36.248 -6.299  -11.050 1.00 23.60 ? 4   GLY B C   1 
ATOM   1820 O O   . GLY B 1 4   ? -36.110 -5.661  -12.096 1.00 23.91 ? 4   GLY B O   1 
ATOM   1821 N N   . GLU B 1 5   ? -35.736 -7.519  -10.876 1.00 26.68 ? 5   GLU B N   1 
ATOM   1822 C CA  . GLU B 1 5   ? -34.972 -8.165  -11.939 1.00 30.41 ? 5   GLU B CA  1 
ATOM   1823 C C   . GLU B 1 5   ? -35.834 -8.412  -13.173 1.00 29.17 ? 5   GLU B C   1 
ATOM   1824 O O   . GLU B 1 5   ? -35.347 -8.330  -14.307 1.00 26.72 ? 5   GLU B O   1 
ATOM   1825 C CB  . GLU B 1 5   ? -34.381 -9.481  -11.436 1.00 32.40 ? 5   GLU B CB  1 
ATOM   1826 C CG  . GLU B 1 5   ? -33.357 -9.331  -10.331 1.00 35.23 ? 5   GLU B CG  1 
ATOM   1827 C CD  . GLU B 1 5   ? -32.780 -10.668 -9.904  1.00 46.49 ? 5   GLU B CD  1 
ATOM   1828 O OE1 . GLU B 1 5   ? -31.583 -10.720 -9.543  1.00 46.36 ? 5   GLU B OE1 1 
ATOM   1829 O OE2 . GLU B 1 5   ? -33.522 -11.676 -9.965  1.00 44.65 ? 5   GLU B OE2 1 
ATOM   1830 N N   . GLU B 1 6   ? -37.118 -8.667  -12.948 1.00 26.66 ? 6   GLU B N   1 
ATOM   1831 C CA  . GLU B 1 6   ? -38.065 -8.855  -14.039 1.00 31.97 ? 6   GLU B CA  1 
ATOM   1832 C C   . GLU B 1 6   ? -38.190 -7.598  -14.899 1.00 28.73 ? 6   GLU B C   1 
ATOM   1833 O O   . GLU B 1 6   ? -38.522 -7.682  -16.081 1.00 27.14 ? 6   GLU B O   1 
ATOM   1834 C CB  . GLU B 1 6   ? -39.437 -9.257  -13.493 1.00 33.21 ? 6   GLU B CB  1 
ATOM   1835 C CG  . GLU B 1 6   ? -39.381 -10.052 -12.199 1.00 41.23 ? 6   GLU B CG  1 
ATOM   1836 C CD  . GLU B 1 6   ? -39.783 -11.501 -12.388 1.00 49.68 ? 6   GLU B CD  1 
ATOM   1837 O OE1 . GLU B 1 6   ? -39.007 -12.392 -11.982 1.00 44.55 ? 6   GLU B OE1 1 
ATOM   1838 O OE2 . GLU B 1 6   ? -40.874 -11.750 -12.942 1.00 49.34 ? 6   GLU B OE2 1 
ATOM   1839 N N   . LEU B 1 7   ? -37.927 -6.435  -14.307 1.00 22.57 ? 7   LEU B N   1 
ATOM   1840 C CA  . LEU B 1 7   ? -38.031 -5.179  -15.045 1.00 23.84 ? 7   LEU B CA  1 
ATOM   1841 C C   . LEU B 1 7   ? -36.926 -5.007  -16.073 1.00 23.27 ? 7   LEU B C   1 
ATOM   1842 O O   . LEU B 1 7   ? -36.988 -4.064  -16.871 1.00 23.04 ? 7   LEU B O   1 
ATOM   1843 C CB  . LEU B 1 7   ? -37.992 -3.987  -14.094 1.00 20.61 ? 7   LEU B CB  1 
ATOM   1844 C CG  . LEU B 1 7   ? -39.172 -3.860  -13.130 1.00 24.69 ? 7   LEU B CG  1 
ATOM   1845 C CD1 . LEU B 1 7   ? -38.988 -2.637  -12.248 1.00 18.83 ? 7   LEU B CD1 1 
ATOM   1846 C CD2 . LEU B 1 7   ? -40.524 -3.836  -13.851 1.00 21.66 ? 7   LEU B CD2 1 
ATOM   1847 N N   . PHE B 1 8   ? -35.917 -5.873  -16.079 1.00 21.22 ? 8   PHE B N   1 
ATOM   1848 C CA  . PHE B 1 8   ? -34.807 -5.717  -17.007 1.00 22.90 ? 8   PHE B CA  1 
ATOM   1849 C C   . PHE B 1 8   ? -34.725 -6.833  -18.041 1.00 24.61 ? 8   PHE B C   1 
ATOM   1850 O O   . PHE B 1 8   ? -33.692 -6.961  -18.705 1.00 23.11 ? 8   PHE B O   1 
ATOM   1851 C CB  . PHE B 1 8   ? -33.491 -5.630  -16.230 1.00 21.47 ? 8   PHE B CB  1 
ATOM   1852 C CG  . PHE B 1 8   ? -33.375 -4.406  -15.367 1.00 16.27 ? 8   PHE B CG  1 
ATOM   1853 C CD1 . PHE B 1 8   ? -33.927 -4.379  -14.103 1.00 18.20 ? 8   PHE B CD1 1 
ATOM   1854 C CD2 . PHE B 1 8   ? -32.700 -3.292  -15.820 1.00 15.99 ? 8   PHE B CD2 1 
ATOM   1855 C CE1 . PHE B 1 8   ? -33.805 -3.257  -13.297 1.00 17.45 ? 8   PHE B CE1 1 
ATOM   1856 C CE2 . PHE B 1 8   ? -32.582 -2.160  -15.016 1.00 14.92 ? 8   PHE B CE2 1 
ATOM   1857 C CZ  . PHE B 1 8   ? -33.131 -2.151  -13.756 1.00 14.08 ? 8   PHE B CZ  1 
ATOM   1858 N N   . THR B 1 9   ? -35.785 -7.633  -18.212 1.00 24.96 ? 9   THR B N   1 
ATOM   1859 C CA  . THR B 1 9   ? -35.696 -8.778  -19.124 1.00 25.16 ? 9   THR B CA  1 
ATOM   1860 C C   . THR B 1 9   ? -35.626 -8.361  -20.586 1.00 27.82 ? 9   THR B C   1 
ATOM   1861 O O   . THR B 1 9   ? -35.187 -9.159  -21.425 1.00 28.62 ? 9   THR B O   1 
ATOM   1862 C CB  . THR B 1 9   ? -36.884 -9.723  -18.928 1.00 26.76 ? 9   THR B CB  1 
ATOM   1863 O OG1 . THR B 1 9   ? -38.106 -9.004  -19.132 1.00 28.82 ? 9   THR B OG1 1 
ATOM   1864 C CG2 . THR B 1 9   ? -36.882 -10.300 -17.517 1.00 34.88 ? 9   THR B CG2 1 
ATOM   1865 N N   . GLY B 1 10  ? -36.053 -7.145  -20.916 1.00 25.25 ? 10  GLY B N   1 
ATOM   1866 C CA  . GLY B 1 10  ? -35.949 -6.652  -22.277 1.00 26.48 ? 10  GLY B CA  1 
ATOM   1867 C C   . GLY B 1 10  ? -35.256 -5.305  -22.381 1.00 23.78 ? 10  GLY B C   1 
ATOM   1868 O O   . GLY B 1 10  ? -34.498 -4.914  -21.486 1.00 23.20 ? 10  GLY B O   1 
ATOM   1869 N N   . VAL B 1 11  ? -35.507 -4.575  -23.458 1.00 23.11 ? 11  VAL B N   1 
ATOM   1870 C CA  . VAL B 1 11  ? -34.834 -3.300  -23.674 1.00 21.38 ? 11  VAL B CA  1 
ATOM   1871 C C   . VAL B 1 11  ? -35.526 -2.248  -22.819 1.00 20.62 ? 11  VAL B C   1 
ATOM   1872 O O   . VAL B 1 11  ? -36.758 -2.172  -22.802 1.00 22.20 ? 11  VAL B O   1 
ATOM   1873 C CB  . VAL B 1 11  ? -34.868 -2.921  -25.163 1.00 22.41 ? 11  VAL B CB  1 
ATOM   1874 C CG1 . VAL B 1 11  ? -34.439 -1.479  -25.367 1.00 22.01 ? 11  VAL B CG1 1 
ATOM   1875 C CG2 . VAL B 1 11  ? -34.021 -3.908  -25.993 1.00 25.44 ? 11  VAL B CG2 1 
ATOM   1876 N N   . VAL B 1 12  ? -34.745 -1.431  -22.119 1.00 19.83 ? 12  VAL B N   1 
ATOM   1877 C CA  . VAL B 1 12  ? -35.257 -0.438  -21.179 1.00 15.43 ? 12  VAL B CA  1 
ATOM   1878 C C   . VAL B 1 12  ? -34.753 0.936   -21.596 1.00 15.39 ? 12  VAL B C   1 
ATOM   1879 O O   . VAL B 1 12  ? -33.543 1.127   -21.729 1.00 15.78 ? 12  VAL B O   1 
ATOM   1880 C CB  . VAL B 1 12  ? -34.840 -0.731  -19.726 1.00 18.32 ? 12  VAL B CB  1 
ATOM   1881 C CG1 . VAL B 1 12  ? -35.403 0.329   -18.800 1.00 14.58 ? 12  VAL B CG1 1 
ATOM   1882 C CG2 . VAL B 1 12  ? -35.340 -2.112  -19.292 1.00 16.56 ? 12  VAL B CG2 1 
ATOM   1883 N N   . PRO B 1 13  ? -35.625 1.928   -21.777 1.00 16.96 ? 13  PRO B N   1 
ATOM   1884 C CA  . PRO B 1 13  ? -35.140 3.284   -22.072 1.00 14.23 ? 13  PRO B CA  1 
ATOM   1885 C C   . PRO B 1 13  ? -34.434 3.882   -20.862 1.00 12.01 ? 13  PRO B C   1 
ATOM   1886 O O   . PRO B 1 13  ? -34.829 3.652   -19.722 1.00 15.34 ? 13  PRO B O   1 
ATOM   1887 C CB  . PRO B 1 13  ? -36.416 4.069   -22.405 1.00 18.91 ? 13  PRO B CB  1 
ATOM   1888 C CG  . PRO B 1 13  ? -37.538 3.161   -22.267 1.00 22.22 ? 13  PRO B CG  1 
ATOM   1889 C CD  . PRO B 1 13  ? -37.082 1.788   -21.916 1.00 20.40 ? 13  PRO B CD  1 
ATOM   1890 N N   . ILE B 1 14  ? -33.391 4.668   -21.119 1.00 14.04 ? 14  ILE B N   1 
ATOM   1891 C CA  . ILE B 1 14  ? -32.593 5.285   -20.060 1.00 13.28 ? 14  ILE B CA  1 
ATOM   1892 C C   . ILE B 1 14  ? -32.611 6.796   -20.245 1.00 13.64 ? 14  ILE B C   1 
ATOM   1893 O O   . ILE B 1 14  ? -32.498 7.296   -21.371 1.00 13.25 ? 14  ILE B O   1 
ATOM   1894 C CB  . ILE B 1 14  ? -31.139 4.767   -20.064 1.00 12.75 ? 14  ILE B CB  1 
ATOM   1895 C CG1 . ILE B 1 14  ? -31.100 3.282   -19.737 1.00 13.04 ? 14  ILE B CG1 1 
ATOM   1896 C CG2 . ILE B 1 14  ? -30.259 5.571   -19.102 1.00 12.92 ? 14  ILE B CG2 1 
ATOM   1897 C CD1 . ILE B 1 14  ? -29.706 2.694   -19.880 1.00 15.05 ? 14  ILE B CD1 1 
ATOM   1898 N N   . LEU B 1 15  ? -32.759 7.514   -19.130 1.00 13.27 ? 15  LEU B N   1 
ATOM   1899 C CA  . LEU B 1 15  ? -32.604 8.957   -19.066 1.00 12.13 ? 15  LEU B CA  1 
ATOM   1900 C C   . LEU B 1 15  ? -31.580 9.270   -17.987 1.00 11.31 ? 15  LEU B C   1 
ATOM   1901 O O   . LEU B 1 15  ? -31.662 8.720   -16.884 1.00 12.35 ? 15  LEU B O   1 
ATOM   1902 C CB  . LEU B 1 15  ? -33.935 9.633   -18.717 1.00 12.61 ? 15  LEU B CB  1 
ATOM   1903 C CG  . LEU B 1 15  ? -33.855 11.103  -18.319 1.00 14.10 ? 15  LEU B CG  1 
ATOM   1904 C CD1 . LEU B 1 15  ? -33.486 11.952  -19.528 1.00 16.25 ? 15  LEU B CD1 1 
ATOM   1905 C CD2 . LEU B 1 15  ? -35.174 11.552  -17.653 1.00 15.31 ? 15  LEU B CD2 1 
ATOM   1906 N N   . VAL B 1 16  ? -30.627 10.150  -18.294 1.00 11.47 ? 16  VAL B N   1 
ATOM   1907 C CA  . VAL B 1 16  ? -29.649 10.640  -17.329 1.00 10.77 ? 16  VAL B CA  1 
ATOM   1908 C C   . VAL B 1 16  ? -29.756 12.158  -17.275 1.00 11.85 ? 16  VAL B C   1 
ATOM   1909 O O   . VAL B 1 16  ? -29.880 12.821  -18.311 1.00 12.58 ? 16  VAL B O   1 
ATOM   1910 C CB  . VAL B 1 16  ? -28.219 10.203  -17.695 1.00 11.30 ? 16  VAL B CB  1 
ATOM   1911 C CG1 . VAL B 1 16  ? -27.228 10.613  -16.594 1.00 11.14 ? 16  VAL B CG1 1 
ATOM   1912 C CG2 . VAL B 1 16  ? -28.192 8.692   -17.922 1.00 11.86 ? 16  VAL B CG2 1 
ATOM   1913 N N   . GLU B 1 17  ? -29.772 12.703  -16.064 1.00 12.25 ? 17  GLU B N   1 
ATOM   1914 C CA  . GLU B 1 17  ? -29.829 14.145  -15.881 1.00 14.69 ? 17  GLU B CA  1 
ATOM   1915 C C   . GLU B 1 17  ? -28.813 14.477  -14.807 1.00 13.28 ? 17  GLU B C   1 
ATOM   1916 O O   . GLU B 1 17  ? -28.899 13.943  -13.702 1.00 11.80 ? 17  GLU B O   1 
ATOM   1917 C CB  . GLU B 1 17  ? -31.237 14.610  -15.468 1.00 12.33 ? 17  GLU B CB  1 
ATOM   1918 C CG  . GLU B 1 17  ? -32.308 14.482  -16.575 1.00 12.91 ? 17  GLU B CG  1 
ATOM   1919 C CD  . GLU B 1 17  ? -32.063 15.361  -17.795 1.00 15.59 ? 17  GLU B CD  1 
ATOM   1920 O OE1 . GLU B 1 17  ? -31.148 16.215  -17.773 1.00 15.26 ? 17  GLU B OE1 1 
ATOM   1921 O OE2 . GLU B 1 17  ? -32.797 15.189  -18.794 1.00 16.69 ? 17  GLU B OE2 1 
ATOM   1922 N N   . LEU B 1 18  ? -27.855 15.339  -15.132 1.00 12.28 ? 18  LEU B N   1 
ATOM   1923 C CA  . LEU B 1 18  ? -26.789 15.706  -14.216 1.00 11.62 ? 18  LEU B CA  1 
ATOM   1924 C C   . LEU B 1 18  ? -26.786 17.214  -14.040 1.00 14.21 ? 18  LEU B C   1 
ATOM   1925 O O   . LEU B 1 18  ? -26.801 17.957  -15.024 1.00 14.21 ? 18  LEU B O   1 
ATOM   1926 C CB  . LEU B 1 18  ? -25.421 15.239  -14.738 1.00 12.69 ? 18  LEU B CB  1 
ATOM   1927 C CG  . LEU B 1 18  ? -24.261 15.630  -13.814 1.00 14.81 ? 18  LEU B CG  1 
ATOM   1928 C CD1 . LEU B 1 18  ? -23.312 14.456  -13.692 1.00 18.59 ? 18  LEU B CD1 1 
ATOM   1929 C CD2 . LEU B 1 18  ? -23.511 16.881  -14.264 1.00 15.86 ? 18  LEU B CD2 1 
ATOM   1930 N N   . ASP B 1 19  ? -26.748 17.653  -12.791 1.00 12.35 ? 19  ASP B N   1 
ATOM   1931 C CA  . ASP B 1 19  ? -26.611 19.054  -12.421 1.00 16.49 ? 19  ASP B CA  1 
ATOM   1932 C C   . ASP B 1 19  ? -25.248 19.198  -11.752 1.00 13.98 ? 19  ASP B C   1 
ATOM   1933 O O   . ASP B 1 19  ? -24.982 18.531  -10.744 1.00 12.95 ? 19  ASP B O   1 
ATOM   1934 C CB  . ASP B 1 19  ? -27.772 19.448  -11.496 1.00 20.22 ? 19  ASP B CB  1 
ATOM   1935 C CG  . ASP B 1 19  ? -27.528 20.722  -10.713 1.00 23.30 ? 19  ASP B CG  1 
ATOM   1936 O OD1 . ASP B 1 19  ? -26.998 21.696  -11.279 1.00 23.19 ? 19  ASP B OD1 1 
ATOM   1937 O OD2 . ASP B 1 19  ? -27.968 20.769  -9.538  1.00 25.89 ? 19  ASP B OD2 1 
ATOM   1938 N N   . GLY B 1 20  ? -24.370 20.010  -12.342 1.00 13.87 ? 20  GLY B N   1 
ATOM   1939 C CA  . GLY B 1 20  ? -22.977 20.068  -11.928 1.00 13.41 ? 20  GLY B CA  1 
ATOM   1940 C C   . GLY B 1 20  ? -22.471 21.463  -11.610 1.00 14.38 ? 20  GLY B C   1 
ATOM   1941 O O   . GLY B 1 20  ? -22.910 22.455  -12.194 1.00 14.96 ? 20  GLY B O   1 
ATOM   1942 N N   . ASP B 1 21  ? -21.507 21.520  -10.695 1.00 14.47 ? 21  ASP B N   1 
ATOM   1943 C CA  . ASP B 1 21  ? -20.819 22.757  -10.330 1.00 15.94 ? 21  ASP B CA  1 
ATOM   1944 C C   . ASP B 1 21  ? -19.395 22.345  -9.994  1.00 13.52 ? 21  ASP B C   1 
ATOM   1945 O O   . ASP B 1 21  ? -19.202 21.625  -9.018  1.00 15.78 ? 21  ASP B O   1 
ATOM   1946 C CB  . ASP B 1 21  ? -21.492 23.435  -9.127  1.00 12.50 ? 21  ASP B CB  1 
ATOM   1947 C CG  . ASP B 1 21  ? -20.812 24.762  -8.718  1.00 21.30 ? 21  ASP B CG  1 
ATOM   1948 O OD1 . ASP B 1 21  ? -19.639 24.967  -9.041  1.00 22.44 ? 21  ASP B OD1 1 
ATOM   1949 O OD2 . ASP B 1 21  ? -21.422 25.576  -7.992  1.00 25.41 ? 21  ASP B OD2 1 
ATOM   1950 N N   . VAL B 1 22  ? -18.416 22.773  -10.795 1.00 14.17 ? 22  VAL B N   1 
ATOM   1951 C CA  . VAL B 1 22  ? -16.999 22.481  -10.553 1.00 12.84 ? 22  VAL B CA  1 
ATOM   1952 C C   . VAL B 1 22  ? -16.249 23.806  -10.436 1.00 14.29 ? 22  VAL B C   1 
ATOM   1953 O O   . VAL B 1 22  ? -16.143 24.556  -11.416 1.00 13.12 ? 22  VAL B O   1 
ATOM   1954 C CB  . VAL B 1 22  ? -16.411 21.597  -11.661 1.00 13.21 ? 22  VAL B CB  1 
ATOM   1955 C CG1 . VAL B 1 22  ? -14.918 21.383  -11.433 1.00 14.51 ? 22  VAL B CG1 1 
ATOM   1956 C CG2 . VAL B 1 22  ? -17.129 20.258  -11.657 1.00 11.63 ? 22  VAL B CG2 1 
ATOM   1957 N N   . ASN B 1 23  ? -15.737 24.109  -9.235  1.00 15.55 ? 23  ASN B N   1 
ATOM   1958 C CA  . ASN B 1 23  ? -15.040 25.375  -9.001  1.00 16.35 ? 23  ASN B CA  1 
ATOM   1959 C C   . ASN B 1 23  ? -15.908 26.562  -9.415  1.00 18.65 ? 23  ASN B C   1 
ATOM   1960 O O   . ASN B 1 23  ? -15.425 27.552  -9.970  1.00 18.54 ? 23  ASN B O   1 
ATOM   1961 C CB  . ASN B 1 23  ? -13.690 25.422  -9.735  1.00 20.98 ? 23  ASN B CB  1 
ATOM   1962 C CG  . ASN B 1 23  ? -12.569 24.721  -8.974  1.00 16.39 ? 23  ASN B CG  1 
ATOM   1963 O OD1 . ASN B 1 23  ? -12.803 23.775  -8.244  1.00 17.67 ? 23  ASN B OD1 1 
ATOM   1964 N ND2 . ASN B 1 23  ? -11.340 25.226  -9.123  1.00 18.21 ? 23  ASN B ND2 1 
ATOM   1965 N N   . GLY B 1 24  ? -17.216 26.454  -9.182  1.00 16.65 ? 24  GLY B N   1 
ATOM   1966 C CA  . GLY B 1 24  ? -18.118 27.521  -9.565  1.00 19.36 ? 24  GLY B CA  1 
ATOM   1967 C C   . GLY B 1 24  ? -18.509 27.550  -11.026 1.00 19.06 ? 24  GLY B C   1 
ATOM   1968 O O   . GLY B 1 24  ? -19.337 28.386  -11.407 1.00 20.15 ? 24  GLY B O   1 
ATOM   1969 N N   . HIS B 1 25  ? -17.914 26.701  -11.866 1.00 16.76 ? 25  HIS B N   1 
ATOM   1970 C CA  . HIS B 1 25  ? -18.344 26.559  -13.255 1.00 18.46 ? 25  HIS B CA  1 
ATOM   1971 C C   . HIS B 1 25  ? -19.544 25.625  -13.271 1.00 18.75 ? 25  HIS B C   1 
ATOM   1972 O O   . HIS B 1 25  ? -19.407 24.419  -13.029 1.00 16.15 ? 25  HIS B O   1 
ATOM   1973 C CB  . HIS B 1 25  ? -17.210 26.019  -14.122 1.00 19.39 ? 25  HIS B CB  1 
ATOM   1974 C CG  . HIS B 1 25  ? -15.965 26.849  -14.065 1.00 20.66 ? 25  HIS B CG  1 
ATOM   1975 N ND1 . HIS B 1 25  ? -15.893 28.118  -14.597 1.00 27.82 ? 25  HIS B ND1 1 
ATOM   1976 C CD2 . HIS B 1 25  ? -14.753 26.606  -13.512 1.00 21.37 ? 25  HIS B CD2 1 
ATOM   1977 C CE1 . HIS B 1 25  ? -14.688 28.617  -14.385 1.00 22.17 ? 25  HIS B CE1 1 
ATOM   1978 N NE2 . HIS B 1 25  ? -13.977 27.719  -13.728 1.00 25.06 ? 25  HIS B NE2 1 
ATOM   1979 N N   . LYS B 1 26  ? -20.721 26.181  -13.515 1.00 18.52 ? 26  LYS B N   1 
ATOM   1980 C CA  . LYS B 1 26  ? -21.960 25.430  -13.432 1.00 14.60 ? 26  LYS B CA  1 
ATOM   1981 C C   . LYS B 1 26  ? -22.341 24.921  -14.818 1.00 16.53 ? 26  LYS B C   1 
ATOM   1982 O O   . LYS B 1 26  ? -22.059 25.566  -15.832 1.00 16.63 ? 26  LYS B O   1 
ATOM   1983 C CB  . LYS B 1 26  ? -23.073 26.299  -12.847 1.00 17.95 ? 26  LYS B CB  1 
ATOM   1984 C CG  . LYS B 1 26  ? -22.783 26.869  -11.450 1.00 19.39 ? 26  LYS B CG  1 
ATOM   1985 C CD  . LYS B 1 26  ? -23.879 27.863  -10.959 1.00 23.58 ? 26  LYS B CD  1 
ATOM   1986 C CE  . LYS B 1 26  ? -23.557 29.314  -11.394 1.00 26.89 ? 26  LYS B CE  1 
ATOM   1987 N NZ  . LYS B 1 26  ? -24.684 30.355  -11.358 1.00 22.19 ? 26  LYS B NZ  1 
ATOM   1988 N N   . PHE B 1 27  ? -22.981 23.752  -14.856 1.00 14.12 ? 27  PHE B N   1 
ATOM   1989 C CA  . PHE B 1 27  ? -23.315 23.115  -16.129 1.00 15.61 ? 27  PHE B CA  1 
ATOM   1990 C C   . PHE B 1 27  ? -24.376 22.044  -15.930 1.00 14.32 ? 27  PHE B C   1 
ATOM   1991 O O   . PHE B 1 27  ? -24.662 21.610  -14.813 1.00 15.90 ? 27  PHE B O   1 
ATOM   1992 C CB  . PHE B 1 27  ? -22.065 22.525  -16.793 1.00 14.26 ? 27  PHE B CB  1 
ATOM   1993 C CG  . PHE B 1 27  ? -21.424 21.408  -16.010 1.00 11.43 ? 27  PHE B CG  1 
ATOM   1994 C CD1 . PHE B 1 27  ? -20.556 21.700  -14.972 1.00 15.70 ? 27  PHE B CD1 1 
ATOM   1995 C CD2 . PHE B 1 27  ? -21.667 20.079  -16.313 1.00 11.13 ? 27  PHE B CD2 1 
ATOM   1996 C CE1 . PHE B 1 27  ? -19.943 20.687  -14.251 1.00 13.49 ? 27  PHE B CE1 1 
ATOM   1997 C CE2 . PHE B 1 27  ? -21.068 19.052  -15.579 1.00 12.71 ? 27  PHE B CE2 1 
ATOM   1998 C CZ  . PHE B 1 27  ? -20.201 19.357  -14.563 1.00 13.82 ? 27  PHE B CZ  1 
ATOM   1999 N N   . SER B 1 28  ? -24.947 21.608  -17.047 1.00 15.76 ? 28  SER B N   1 
ATOM   2000 C CA  . SER B 1 28  ? -25.934 20.545  -17.022 1.00 12.25 ? 28  SER B CA  1 
ATOM   2001 C C   . SER B 1 28  ? -25.628 19.578  -18.157 1.00 12.88 ? 28  SER B C   1 
ATOM   2002 O O   . SER B 1 28  ? -25.163 19.981  -19.230 1.00 12.54 ? 28  SER B O   1 
ATOM   2003 C CB  . SER B 1 28  ? -27.357 21.126  -17.130 1.00 15.64 ? 28  SER B CB  1 
ATOM   2004 O OG  . SER B 1 28  ? -28.338 20.105  -17.180 1.00 17.73 ? 28  SER B OG  1 
ATOM   2005 N N   . VAL B 1 29  ? -25.855 18.297  -17.899 1.00 10.49 ? 29  VAL B N   1 
ATOM   2006 C CA  . VAL B 1 29  ? -25.697 17.261  -18.910 1.00 11.75 ? 29  VAL B CA  1 
ATOM   2007 C C   . VAL B 1 29  ? -26.980 16.448  -18.955 1.00 12.67 ? 29  VAL B C   1 
ATOM   2008 O O   . VAL B 1 29  ? -27.546 16.115  -17.910 1.00 14.25 ? 29  VAL B O   1 
ATOM   2009 C CB  . VAL B 1 29  ? -24.490 16.346  -18.608 1.00 10.51 ? 29  VAL B CB  1 
ATOM   2010 C CG1 . VAL B 1 29  ? -24.501 15.112  -19.557 1.00 8.44  ? 29  VAL B CG1 1 
ATOM   2011 C CG2 . VAL B 1 29  ? -23.187 17.121  -18.737 1.00 10.74 ? 29  VAL B CG2 1 
ATOM   2012 N N   . SER B 1 30  ? -27.447 16.130  -20.157 1.00 14.02 ? 30  SER B N   1 
ATOM   2013 C CA  . SER B 1 30  ? -28.582 15.231  -20.329 1.00 12.12 ? 30  SER B CA  1 
ATOM   2014 C C   . SER B 1 30  ? -28.139 14.057  -21.186 1.00 15.21 ? 30  SER B C   1 
ATOM   2015 O O   . SER B 1 30  ? -27.414 14.250  -22.161 1.00 17.11 ? 30  SER B O   1 
ATOM   2016 C CB  . SER B 1 30  ? -29.758 15.921  -21.014 1.00 16.85 ? 30  SER B CB  1 
ATOM   2017 O OG  . SER B 1 30  ? -30.329 16.907  -20.171 1.00 20.67 ? 30  SER B OG  1 
ATOM   2018 N N   . GLY B 1 31  ? -28.597 12.859  -20.848 1.00 12.11 ? 31  GLY B N   1 
ATOM   2019 C CA  . GLY B 1 31  ? -28.328 11.688  -21.661 1.00 12.09 ? 31  GLY B CA  1 
ATOM   2020 C C   . GLY B 1 31  ? -29.586 10.875  -21.878 1.00 13.44 ? 31  GLY B C   1 
ATOM   2021 O O   . GLY B 1 31  ? -30.501 10.877  -21.057 1.00 12.18 ? 31  GLY B O   1 
ATOM   2022 N N   . GLU B 1 32  ? -29.618 10.161  -23.005 1.00 12.50 ? 32  GLU B N   1 
ATOM   2023 C CA  . GLU B 1 32  ? -30.719 9.248   -23.273 1.00 13.58 ? 32  GLU B CA  1 
ATOM   2024 C C   . GLU B 1 32  ? -30.247 8.147   -24.204 1.00 14.21 ? 32  GLU B C   1 
ATOM   2025 O O   . GLU B 1 32  ? -29.250 8.290   -24.911 1.00 14.12 ? 32  GLU B O   1 
ATOM   2026 C CB  . GLU B 1 32  ? -31.934 9.980   -23.848 1.00 17.12 ? 32  GLU B CB  1 
ATOM   2027 C CG  . GLU B 1 32  ? -31.645 10.845  -25.034 1.00 23.84 ? 32  GLU B CG  1 
ATOM   2028 C CD  . GLU B 1 32  ? -32.936 11.343  -25.691 1.00 42.21 ? 32  GLU B CD  1 
ATOM   2029 O OE1 . GLU B 1 32  ? -33.255 10.888  -26.813 1.00 41.86 ? 32  GLU B OE1 1 
ATOM   2030 O OE2 . GLU B 1 32  ? -33.650 12.161  -25.055 1.00 41.26 ? 32  GLU B OE2 1 
ATOM   2031 N N   . GLY B 1 33  ? -30.969 7.033   -24.163 1.00 16.59 ? 33  GLY B N   1 
ATOM   2032 C CA  . GLY B 1 33  ? -30.607 5.853   -24.915 1.00 17.29 ? 33  GLY B CA  1 
ATOM   2033 C C   . GLY B 1 33  ? -31.290 4.661   -24.300 1.00 15.25 ? 33  GLY B C   1 
ATOM   2034 O O   . GLY B 1 33  ? -32.422 4.792   -23.821 1.00 15.21 ? 33  GLY B O   1 
ATOM   2035 N N   . GLU B 1 34  ? -30.642 3.496   -24.280 1.00 17.15 ? 34  GLU B N   1 
ATOM   2036 C CA  . GLU B 1 34  ? -31.320 2.351   -23.702 1.00 15.90 ? 34  GLU B CA  1 
ATOM   2037 C C   . GLU B 1 34  ? -30.312 1.350   -23.175 1.00 12.22 ? 34  GLU B C   1 
ATOM   2038 O O   . GLU B 1 34  ? -29.127 1.381   -23.511 1.00 14.43 ? 34  GLU B O   1 
ATOM   2039 C CB  . GLU B 1 34  ? -32.248 1.658   -24.708 1.00 22.75 ? 34  GLU B CB  1 
ATOM   2040 C CG  . GLU B 1 34  ? -31.704 1.625   -26.093 1.00 26.41 ? 34  GLU B CG  1 
ATOM   2041 C CD  . GLU B 1 34  ? -32.744 1.237   -27.137 1.00 31.22 ? 34  GLU B CD  1 
ATOM   2042 O OE1 . GLU B 1 34  ? -32.435 0.332   -27.939 1.00 37.48 ? 34  GLU B OE1 1 
ATOM   2043 O OE2 . GLU B 1 34  ? -33.842 1.836   -27.178 1.00 33.62 ? 34  GLU B OE2 1 
ATOM   2044 N N   . GLY B 1 35  ? -30.818 0.460   -22.334 1.00 16.30 ? 35  GLY B N   1 
ATOM   2045 C CA  . GLY B 1 35  ? -30.008 -0.592  -21.754 1.00 15.28 ? 35  GLY B CA  1 
ATOM   2046 C C   . GLY B 1 35  ? -30.678 -1.929  -21.983 1.00 17.47 ? 35  GLY B C   1 
ATOM   2047 O O   . GLY B 1 35  ? -31.904 -2.033  -22.030 1.00 16.91 ? 35  GLY B O   1 
ATOM   2048 N N   . ASP B 1 36  ? -29.850 -2.957  -22.170 1.00 17.88 ? 36  ASP B N   1 
ATOM   2049 C CA  . ASP B 1 36  ? -30.338 -4.318  -22.392 1.00 18.03 ? 36  ASP B CA  1 
ATOM   2050 C C   . ASP B 1 36  ? -29.502 -5.221  -21.483 1.00 16.62 ? 36  ASP B C   1 
ATOM   2051 O O   . ASP B 1 36  ? -28.439 -5.710  -21.879 1.00 17.51 ? 36  ASP B O   1 
ATOM   2052 C CB  . ASP B 1 36  ? -30.231 -4.714  -23.874 1.00 22.23 ? 36  ASP B CB  1 
ATOM   2053 C CG  . ASP B 1 36  ? -31.122 -5.894  -24.235 1.00 22.43 ? 36  ASP B CG  1 
ATOM   2054 O OD1 . ASP B 1 36  ? -31.579 -6.596  -23.319 1.00 25.90 ? 36  ASP B OD1 1 
ATOM   2055 O OD2 . ASP B 1 36  ? -31.369 -6.114  -25.439 1.00 27.31 ? 36  ASP B OD2 1 
ATOM   2056 N N   . ALA B 1 37  ? -29.994 -5.435  -20.257 1.00 15.37 ? 37  ALA B N   1 
ATOM   2057 C CA  . ALA B 1 37  ? -29.254 -6.203  -19.263 1.00 17.09 ? 37  ALA B CA  1 
ATOM   2058 C C   . ALA B 1 37  ? -29.000 -7.637  -19.708 1.00 21.53 ? 37  ALA B C   1 
ATOM   2059 O O   . ALA B 1 37  ? -28.100 -8.289  -19.166 1.00 21.10 ? 37  ALA B O   1 
ATOM   2060 C CB  . ALA B 1 37  ? -30.008 -6.202  -17.931 1.00 20.54 ? 37  ALA B CB  1 
ATOM   2061 N N   . THR B 1 38  ? -29.771 -8.141  -20.677 1.00 17.62 ? 38  THR B N   1 
ATOM   2062 C CA  . THR B 1 38  ? -29.534 -9.486  -21.194 1.00 20.35 ? 38  THR B CA  1 
ATOM   2063 C C   . THR B 1 38  ? -28.139 -9.592  -21.795 1.00 23.10 ? 38  THR B C   1 
ATOM   2064 O O   . THR B 1 38  ? -27.522 -10.667 -21.750 1.00 20.25 ? 38  THR B O   1 
ATOM   2065 C CB  . THR B 1 38  ? -30.624 -9.835  -22.220 1.00 22.54 ? 38  THR B CB  1 
ATOM   2066 O OG1 . THR B 1 38  ? -31.877 -9.944  -21.536 1.00 27.30 ? 38  THR B OG1 1 
ATOM   2067 C CG2 . THR B 1 38  ? -30.354 -11.174 -22.887 1.00 30.58 ? 38  THR B CG2 1 
ATOM   2068 N N   . TYR B 1 39  ? -27.622 -8.472  -22.326 1.00 18.39 ? 39  TYR B N   1 
ATOM   2069 C CA  . TYR B 1 39  ? -26.292 -8.353  -22.915 1.00 19.41 ? 39  TYR B CA  1 
ATOM   2070 C C   . TYR B 1 39  ? -25.352 -7.482  -22.095 1.00 18.11 ? 39  TYR B C   1 
ATOM   2071 O O   . TYR B 1 39  ? -24.207 -7.265  -22.512 1.00 19.02 ? 39  TYR B O   1 
ATOM   2072 C CB  . TYR B 1 39  ? -26.397 -7.771  -24.337 1.00 21.60 ? 39  TYR B CB  1 
ATOM   2073 C CG  . TYR B 1 39  ? -27.352 -8.524  -25.245 1.00 22.66 ? 39  TYR B CG  1 
ATOM   2074 C CD1 . TYR B 1 39  ? -27.027 -9.775  -25.733 1.00 25.98 ? 39  TYR B CD1 1 
ATOM   2075 C CD2 . TYR B 1 39  ? -28.590 -8.009  -25.571 1.00 26.35 ? 39  TYR B CD2 1 
ATOM   2076 C CE1 . TYR B 1 39  ? -27.879 -10.491 -26.532 1.00 27.97 ? 39  TYR B CE1 1 
ATOM   2077 C CE2 . TYR B 1 39  ? -29.461 -8.723  -26.382 1.00 31.65 ? 39  TYR B CE2 1 
ATOM   2078 C CZ  . TYR B 1 39  ? -29.091 -9.966  -26.856 1.00 30.73 ? 39  TYR B CZ  1 
ATOM   2079 O OH  . TYR B 1 39  ? -29.922 -10.705 -27.657 1.00 35.93 ? 39  TYR B OH  1 
ATOM   2080 N N   . GLY B 1 40  ? -25.803 -6.950  -20.961 1.00 15.61 ? 40  GLY B N   1 
ATOM   2081 C CA  . GLY B 1 40  ? -25.038 -5.937  -20.261 1.00 16.07 ? 40  GLY B CA  1 
ATOM   2082 C C   . GLY B 1 40  ? -24.811 -4.677  -21.064 1.00 17.07 ? 40  GLY B C   1 
ATOM   2083 O O   . GLY B 1 40  ? -23.862 -3.931  -20.792 1.00 16.67 ? 40  GLY B O   1 
ATOM   2084 N N   . LYS B 1 41  ? -25.669 -4.402  -22.046 1.00 15.36 ? 41  LYS B N   1 
ATOM   2085 C CA  . LYS B 1 41  ? -25.389 -3.405  -23.073 1.00 14.34 ? 41  LYS B CA  1 
ATOM   2086 C C   . LYS B 1 41  ? -26.027 -2.061  -22.749 1.00 14.07 ? 41  LYS B C   1 
ATOM   2087 O O   . LYS B 1 41  ? -27.216 -1.996  -22.425 1.00 15.17 ? 41  LYS B O   1 
ATOM   2088 C CB  . LYS B 1 41  ? -25.896 -3.887  -24.429 1.00 16.73 ? 41  LYS B CB  1 
ATOM   2089 C CG  . LYS B 1 41  ? -25.423 -3.022  -25.584 1.00 17.08 ? 41  LYS B CG  1 
ATOM   2090 C CD  . LYS B 1 41  ? -25.622 -3.778  -26.882 1.00 26.22 ? 41  LYS B CD  1 
ATOM   2091 C CE  . LYS B 1 41  ? -26.699 -3.182  -27.741 1.00 33.69 ? 41  LYS B CE  1 
ATOM   2092 N NZ  . LYS B 1 41  ? -26.098 -2.331  -28.786 1.00 32.13 ? 41  LYS B NZ  1 
ATOM   2093 N N   . LEU B 1 42  ? -25.237 -0.995  -22.883 1.00 14.30 ? 42  LEU B N   1 
ATOM   2094 C CA  . LEU B 1 42  ? -25.688 0.384   -22.729 1.00 15.23 ? 42  LEU B CA  1 
ATOM   2095 C C   . LEU B 1 42  ? -25.317 1.160   -23.977 1.00 14.96 ? 42  LEU B C   1 
ATOM   2096 O O   . LEU B 1 42  ? -24.163 1.109   -24.421 1.00 16.31 ? 42  LEU B O   1 
ATOM   2097 C CB  . LEU B 1 42  ? -25.027 1.055   -21.513 1.00 16.75 ? 42  LEU B CB  1 
ATOM   2098 C CG  . LEU B 1 42  ? -25.340 0.488   -20.140 1.00 19.22 ? 42  LEU B CG  1 
ATOM   2099 C CD1 . LEU B 1 42  ? -24.488 1.204   -19.102 1.00 17.69 ? 42  LEU B CD1 1 
ATOM   2100 C CD2 . LEU B 1 42  ? -26.814 0.666   -19.839 1.00 19.33 ? 42  LEU B CD2 1 
ATOM   2101 N N   . THR B 1 43  ? -26.284 1.881   -24.536 1.00 14.78 ? 43  THR B N   1 
ATOM   2102 C CA  . THR B 1 43  ? -26.053 2.803   -25.641 1.00 15.55 ? 43  THR B CA  1 
ATOM   2103 C C   . THR B 1 43  ? -26.692 4.134   -25.270 1.00 14.61 ? 43  THR B C   1 
ATOM   2104 O O   . THR B 1 43  ? -27.908 4.210   -25.075 1.00 14.40 ? 43  THR B O   1 
ATOM   2105 C CB  . THR B 1 43  ? -26.625 2.250   -26.955 1.00 19.14 ? 43  THR B CB  1 
ATOM   2106 O OG1 . THR B 1 43  ? -28.046 2.163   -26.857 1.00 22.55 ? 43  THR B OG1 1 
ATOM   2107 C CG2 . THR B 1 43  ? -26.077 0.872   -27.258 1.00 19.97 ? 43  THR B CG2 1 
ATOM   2108 N N   . LEU B 1 44  ? -25.870 5.168   -25.138 1.00 14.78 ? 44  LEU B N   1 
ATOM   2109 C CA  . LEU B 1 44  ? -26.321 6.448   -24.618 1.00 14.47 ? 44  LEU B CA  1 
ATOM   2110 C C   . LEU B 1 44  ? -25.641 7.579   -25.363 1.00 15.59 ? 44  LEU B C   1 
ATOM   2111 O O   . LEU B 1 44  ? -24.487 7.469   -25.782 1.00 15.00 ? 44  LEU B O   1 
ATOM   2112 C CB  . LEU B 1 44  ? -26.004 6.587   -23.119 1.00 16.65 ? 44  LEU B CB  1 
ATOM   2113 C CG  . LEU B 1 44  ? -26.696 5.547   -22.256 1.00 17.35 ? 44  LEU B CG  1 
ATOM   2114 C CD1 . LEU B 1 44  ? -25.962 5.370   -20.960 1.00 16.84 ? 44  LEU B CD1 1 
ATOM   2115 C CD2 . LEU B 1 44  ? -28.122 5.991   -22.027 1.00 14.93 ? 44  LEU B CD2 1 
ATOM   2116 N N   . LYS B 1 45  ? -26.352 8.689   -25.487 1.00 12.99 ? 45  LYS B N   1 
ATOM   2117 C CA  . LYS B 1 45  ? -25.758 9.917   -25.992 1.00 11.52 ? 45  LYS B CA  1 
ATOM   2118 C C   . LYS B 1 45  ? -25.955 10.999  -24.948 1.00 13.60 ? 45  LYS B C   1 
ATOM   2119 O O   . LYS B 1 45  ? -27.069 11.163  -24.440 1.00 13.35 ? 45  LYS B O   1 
ATOM   2120 C CB  . LYS B 1 45  ? -26.391 10.335  -27.311 1.00 12.85 ? 45  LYS B CB  1 
ATOM   2121 C CG  . LYS B 1 45  ? -25.865 11.642  -27.849 1.00 14.35 ? 45  LYS B CG  1 
ATOM   2122 C CD  . LYS B 1 45  ? -26.529 11.935  -29.203 1.00 17.74 ? 45  LYS B CD  1 
ATOM   2123 C CE  . LYS B 1 45  ? -26.161 13.308  -29.709 1.00 17.77 ? 45  LYS B CE  1 
ATOM   2124 N NZ  . LYS B 1 45  ? -26.906 13.659  -30.970 1.00 16.81 ? 45  LYS B NZ  1 
ATOM   2125 N N   . PHE B 1 46  ? -24.885 11.730  -24.638 1.00 12.83 ? 46  PHE B N   1 
ATOM   2126 C CA  . PHE B 1 46  ? -24.906 12.779  -23.626 1.00 12.64 ? 46  PHE B CA  1 
ATOM   2127 C C   . PHE B 1 46  ? -24.643 14.121  -24.287 1.00 13.30 ? 46  PHE B C   1 
ATOM   2128 O O   . PHE B 1 46  ? -23.793 14.227  -25.169 1.00 14.38 ? 46  PHE B O   1 
ATOM   2129 C CB  . PHE B 1 46  ? -23.853 12.543  -22.536 1.00 11.50 ? 46  PHE B CB  1 
ATOM   2130 C CG  . PHE B 1 46  ? -24.050 11.273  -21.796 1.00 12.30 ? 46  PHE B CG  1 
ATOM   2131 C CD1 . PHE B 1 46  ? -24.902 11.233  -20.710 1.00 11.70 ? 46  PHE B CD1 1 
ATOM   2132 C CD2 . PHE B 1 46  ? -23.408 10.107  -22.199 1.00 12.89 ? 46  PHE B CD2 1 
ATOM   2133 C CE1 . PHE B 1 46  ? -25.118 10.055  -20.016 1.00 10.48 ? 46  PHE B CE1 1 
ATOM   2134 C CE2 . PHE B 1 46  ? -23.619 8.919   -21.510 1.00 12.87 ? 46  PHE B CE2 1 
ATOM   2135 C CZ  . PHE B 1 46  ? -24.466 8.894   -20.417 1.00 13.51 ? 46  PHE B CZ  1 
ATOM   2136 N N   . ILE B 1 47  ? -25.351 15.147  -23.838 1.00 12.51 ? 47  ILE B N   1 
ATOM   2137 C CA  . ILE B 1 47  ? -25.168 16.502  -24.344 1.00 14.31 ? 47  ILE B CA  1 
ATOM   2138 C C   . ILE B 1 47  ? -24.984 17.423  -23.154 1.00 12.27 ? 47  ILE B C   1 
ATOM   2139 O O   . ILE B 1 47  ? -25.679 17.274  -22.144 1.00 12.86 ? 47  ILE B O   1 
ATOM   2140 C CB  . ILE B 1 47  ? -26.382 16.941  -25.190 1.00 14.59 ? 47  ILE B CB  1 
ATOM   2141 C CG1 . ILE B 1 47  ? -26.527 16.007  -26.404 1.00 17.78 ? 47  ILE B CG1 1 
ATOM   2142 C CG2 . ILE B 1 47  ? -26.287 18.414  -25.580 1.00 16.56 ? 47  ILE B CG2 1 
ATOM   2143 C CD1 . ILE B 1 47  ? -27.567 16.459  -27.396 1.00 21.82 ? 47  ILE B CD1 1 
ATOM   2144 N N   . CYS B 1 48  ? -24.033 18.347  -23.261 1.00 13.12 ? 48  CYS B N   1 
ATOM   2145 C CA  . CYS B 1 48  ? -23.933 19.430  -22.295 1.00 12.04 ? 48  CYS B CA  1 
ATOM   2146 C C   . CYS B 1 48  ? -24.888 20.507  -22.782 1.00 16.60 ? 48  CYS B C   1 
ATOM   2147 O O   . CYS B 1 48  ? -24.650 21.132  -23.823 1.00 15.74 ? 48  CYS B O   1 
ATOM   2148 C CB  . CYS B 1 48  ? -22.511 19.954  -22.169 1.00 14.10 ? 48  CYS B CB  1 
ATOM   2149 S SG  . CYS B 1 48  ? -22.410 21.400  -21.068 1.00 14.64 ? 48  CYS B SG  1 
ATOM   2150 N N   . THR B 1 49  ? -25.989 20.676  -22.067 1.00 12.97 ? 49  THR B N   1 
ATOM   2151 C CA  . THR B 1 49  ? -27.100 21.499  -22.518 1.00 18.05 ? 49  THR B CA  1 
ATOM   2152 C C   . THR B 1 49  ? -26.911 22.958  -22.173 1.00 18.67 ? 49  THR B C   1 
ATOM   2153 O O   . THR B 1 49  ? -27.766 23.775  -22.518 1.00 21.20 ? 49  THR B O   1 
ATOM   2154 C CB  . THR B 1 49  ? -28.408 21.019  -21.896 1.00 17.37 ? 49  THR B CB  1 
ATOM   2155 O OG1 . THR B 1 49  ? -28.218 20.831  -20.488 1.00 14.31 ? 49  THR B OG1 1 
ATOM   2156 C CG2 . THR B 1 49  ? -28.853 19.707  -22.529 1.00 15.62 ? 49  THR B CG2 1 
ATOM   2157 N N   . THR B 1 50  ? -25.823 23.299  -21.493 1.00 14.37 ? 50  THR B N   1 
ATOM   2158 C CA  . THR B 1 50  ? -25.558 24.660  -21.078 1.00 16.18 ? 50  THR B CA  1 
ATOM   2159 C C   . THR B 1 50  ? -24.421 25.297  -21.860 1.00 18.73 ? 50  THR B C   1 
ATOM   2160 O O   . THR B 1 50  ? -24.080 26.452  -21.597 1.00 23.43 ? 50  THR B O   1 
ATOM   2161 C CB  . THR B 1 50  ? -25.255 24.688  -19.574 1.00 15.95 ? 50  THR B CB  1 
ATOM   2162 O OG1 . THR B 1 50  ? -24.283 23.677  -19.250 1.00 13.83 ? 50  THR B OG1 1 
ATOM   2163 C CG2 . THR B 1 50  ? -26.510 24.394  -18.792 1.00 13.74 ? 50  THR B CG2 1 
ATOM   2164 N N   . GLY B 1 51  ? -23.840 24.592  -22.822 1.00 19.12 ? 51  GLY B N   1 
ATOM   2165 C CA  . GLY B 1 51  ? -22.760 25.149  -23.611 1.00 20.16 ? 51  GLY B CA  1 
ATOM   2166 C C   . GLY B 1 51  ? -21.585 24.191  -23.620 1.00 19.37 ? 51  GLY B C   1 
ATOM   2167 O O   . GLY B 1 51  ? -21.789 22.987  -23.728 1.00 18.50 ? 51  GLY B O   1 
ATOM   2168 N N   . LYS B 1 52  ? -20.369 24.712  -23.495 1.00 16.49 ? 52  LYS B N   1 
ATOM   2169 C CA  . LYS B 1 52  ? -19.180 23.865  -23.480 1.00 20.42 ? 52  LYS B CA  1 
ATOM   2170 C C   . LYS B 1 52  ? -18.935 23.271  -22.094 1.00 21.21 ? 52  LYS B C   1 
ATOM   2171 O O   . LYS B 1 52  ? -18.885 23.996  -21.101 1.00 14.81 ? 52  LYS B O   1 
ATOM   2172 C CB  . LYS B 1 52  ? -17.953 24.657  -23.937 1.00 22.15 ? 52  LYS B CB  1 
ATOM   2173 C CG  . LYS B 1 52  ? -16.912 23.823  -24.666 1.00 32.23 ? 52  LYS B CG  1 
ATOM   2174 C CD  . LYS B 1 52  ? -15.542 23.964  -24.023 1.00 33.66 ? 52  LYS B CD  1 
ATOM   2175 C CE  . LYS B 1 52  ? -14.448 23.428  -24.931 1.00 33.46 ? 52  LYS B CE  1 
ATOM   2176 N NZ  . LYS B 1 52  ? -13.259 22.971  -24.159 1.00 34.23 ? 52  LYS B NZ  1 
ATOM   2177 N N   . LEU B 1 53  ? -18.781 21.951  -22.033 1.00 15.00 ? 53  LEU B N   1 
ATOM   2178 C CA  . LEU B 1 53  ? -18.531 21.271  -20.762 1.00 14.13 ? 53  LEU B CA  1 
ATOM   2179 C C   . LEU B 1 53  ? -17.255 21.813  -20.116 1.00 14.55 ? 53  LEU B C   1 
ATOM   2180 O O   . LEU B 1 53  ? -16.212 21.863  -20.779 1.00 15.66 ? 53  LEU B O   1 
ATOM   2181 C CB  . LEU B 1 53  ? -18.390 19.766  -21.008 1.00 14.58 ? 53  LEU B CB  1 
ATOM   2182 C CG  . LEU B 1 53  ? -18.549 18.861  -19.794 1.00 14.57 ? 53  LEU B CG  1 
ATOM   2183 C CD1 . LEU B 1 53  ? -19.991 18.942  -19.237 1.00 11.25 ? 53  LEU B CD1 1 
ATOM   2184 C CD2 . LEU B 1 53  ? -18.164 17.415  -20.122 1.00 13.70 ? 53  LEU B CD2 1 
ATOM   2185 N N   . PRO B 1 54  ? -17.280 22.214  -18.838 1.00 14.97 ? 54  PRO B N   1 
ATOM   2186 C CA  . PRO B 1 54  ? -16.059 22.752  -18.214 1.00 13.95 ? 54  PRO B CA  1 
ATOM   2187 C C   . PRO B 1 54  ? -15.053 21.701  -17.757 1.00 15.81 ? 54  PRO B C   1 
ATOM   2188 O O   . PRO B 1 54  ? -13.980 22.081  -17.275 1.00 14.75 ? 54  PRO B O   1 
ATOM   2189 C CB  . PRO B 1 54  ? -16.601 23.551  -17.014 1.00 17.52 ? 54  PRO B CB  1 
ATOM   2190 C CG  . PRO B 1 54  ? -17.880 22.927  -16.686 1.00 16.41 ? 54  PRO B CG  1 
ATOM   2191 C CD  . PRO B 1 54  ? -18.447 22.311  -17.944 1.00 15.16 ? 54  PRO B CD  1 
ATOM   2192 N N   . VAL B 1 55  ? -15.370 20.414  -17.868 1.00 13.55 ? 55  VAL B N   1 
ATOM   2193 C CA  . VAL B 1 55  ? -14.453 19.324  -17.528 1.00 13.63 ? 55  VAL B CA  1 
ATOM   2194 C C   . VAL B 1 55  ? -14.424 18.351  -18.699 1.00 14.09 ? 55  VAL B C   1 
ATOM   2195 O O   . VAL B 1 55  ? -15.279 18.414  -19.594 1.00 14.28 ? 55  VAL B O   1 
ATOM   2196 C CB  . VAL B 1 55  ? -14.872 18.603  -16.224 1.00 13.08 ? 55  VAL B CB  1 
ATOM   2197 C CG1 . VAL B 1 55  ? -14.905 19.591  -15.038 1.00 12.45 ? 55  VAL B CG1 1 
ATOM   2198 C CG2 . VAL B 1 55  ? -16.211 17.912  -16.408 1.00 11.23 ? 55  VAL B CG2 1 
ATOM   2199 N N   . PRO B 1 56  ? -13.443 17.450  -18.741 1.00 12.13 ? 56  PRO B N   1 
ATOM   2200 C CA  . PRO B 1 56  ? -13.394 16.493  -19.858 1.00 12.44 ? 56  PRO B CA  1 
ATOM   2201 C C   . PRO B 1 56  ? -14.483 15.444  -19.732 1.00 14.43 ? 56  PRO B C   1 
ATOM   2202 O O   . PRO B 1 56  ? -14.774 14.955  -18.635 1.00 13.85 ? 56  PRO B O   1 
ATOM   2203 C CB  . PRO B 1 56  ? -11.995 15.872  -19.755 1.00 12.45 ? 56  PRO B CB  1 
ATOM   2204 C CG  . PRO B 1 56  ? -11.201 16.770  -18.810 1.00 12.37 ? 56  PRO B CG  1 
ATOM   2205 C CD  . PRO B 1 56  ? -12.225 17.419  -17.914 1.00 12.73 ? 56  PRO B CD  1 
ATOM   2206 N N   . TRP B 1 57  ? -15.088 15.100  -20.872 1.00 10.65 ? 57  TRP B N   1 
ATOM   2207 C CA  . TRP B 1 57  ? -16.120 14.062  -20.886 1.00 12.31 ? 57  TRP B CA  1 
ATOM   2208 C C   . TRP B 1 57  ? -15.713 12.776  -20.181 1.00 13.38 ? 57  TRP B C   1 
ATOM   2209 O O   . TRP B 1 57  ? -16.528 12.245  -19.411 1.00 11.98 ? 57  TRP B O   1 
ATOM   2210 C CB  . TRP B 1 57  ? -16.552 13.746  -22.323 1.00 13.07 ? 57  TRP B CB  1 
ATOM   2211 C CG  . TRP B 1 57  ? -17.514 14.744  -22.878 1.00 12.53 ? 57  TRP B CG  1 
ATOM   2212 C CD1 . TRP B 1 57  ? -17.258 15.699  -23.826 1.00 15.57 ? 57  TRP B CD1 1 
ATOM   2213 C CD2 . TRP B 1 57  ? -18.882 14.910  -22.498 1.00 12.37 ? 57  TRP B CD2 1 
ATOM   2214 N NE1 . TRP B 1 57  ? -18.392 16.438  -24.071 1.00 12.59 ? 57  TRP B NE1 1 
ATOM   2215 C CE2 . TRP B 1 57  ? -19.402 15.984  -23.263 1.00 12.20 ? 57  TRP B CE2 1 
ATOM   2216 C CE3 . TRP B 1 57  ? -19.722 14.252  -21.592 1.00 11.65 ? 57  TRP B CE3 1 
ATOM   2217 C CZ2 . TRP B 1 57  ? -20.717 16.410  -23.147 1.00 12.40 ? 57  TRP B CZ2 1 
ATOM   2218 C CZ3 . TRP B 1 57  ? -21.022 14.676  -21.470 1.00 10.93 ? 57  TRP B CZ3 1 
ATOM   2219 C CH2 . TRP B 1 57  ? -21.518 15.744  -22.247 1.00 13.77 ? 57  TRP B CH2 1 
ATOM   2220 N N   . PRO B 1 58  ? -14.512 12.220  -20.392 1.00 10.84 ? 58  PRO B N   1 
ATOM   2221 C CA  . PRO B 1 58  ? -14.158 10.976  -19.689 1.00 10.73 ? 58  PRO B CA  1 
ATOM   2222 C C   . PRO B 1 58  ? -14.249 11.069  -18.178 1.00 11.38 ? 58  PRO B C   1 
ATOM   2223 O O   . PRO B 1 58  ? -14.494 10.043  -17.532 1.00 11.74 ? 58  PRO B O   1 
ATOM   2224 C CB  . PRO B 1 58  ? -12.710 10.713  -20.137 1.00 12.18 ? 58  PRO B CB  1 
ATOM   2225 C CG  . PRO B 1 58  ? -12.590 11.416  -21.460 1.00 15.00 ? 58  PRO B CG  1 
ATOM   2226 C CD  . PRO B 1 58  ? -13.448 12.643  -21.330 1.00 12.13 ? 58  PRO B CD  1 
ATOM   2227 N N   . THR B 1 59  ? -14.019 12.245  -17.579 1.00 11.19 ? 59  THR B N   1 
ATOM   2228 C CA  . THR B 1 59  ? -14.079 12.316  -16.120 1.00 10.78 ? 59  THR B CA  1 
ATOM   2229 C C   . THR B 1 59  ? -15.488 12.117  -15.588 1.00 12.07 ? 59  THR B C   1 
ATOM   2230 O O   . THR B 1 59  ? -15.644 11.865  -14.387 1.00 9.72  ? 59  THR B O   1 
ATOM   2231 C CB  . THR B 1 59  ? -13.522 13.648  -15.596 1.00 11.01 ? 59  THR B CB  1 
ATOM   2232 O OG1 . THR B 1 59  ? -14.408 14.724  -15.936 1.00 11.73 ? 59  THR B OG1 1 
ATOM   2233 C CG2 . THR B 1 59  ? -12.143 13.918  -16.164 1.00 9.85  ? 59  THR B CG2 1 
ATOM   2234 N N   . LEU B 1 60  ? -16.511 12.202  -16.447 1.00 10.41 ? 60  LEU B N   1 
ATOM   2235 C CA  . LEU B 1 60  ? -17.894 12.034  -16.015 1.00 10.03 ? 60  LEU B CA  1 
ATOM   2236 C C   . LEU B 1 60  ? -18.453 10.646  -16.272 1.00 10.86 ? 60  LEU B C   1 
ATOM   2237 O O   . LEU B 1 60  ? -19.585 10.380  -15.859 1.00 10.86 ? 60  LEU B O   1 
ATOM   2238 C CB  . LEU B 1 60  ? -18.816 13.074  -16.683 1.00 9.40  ? 60  LEU B CB  1 
ATOM   2239 C CG  . LEU B 1 60  ? -18.529 14.553  -16.393 1.00 10.59 ? 60  LEU B CG  1 
ATOM   2240 C CD1 . LEU B 1 60  ? -19.466 15.527  -17.158 1.00 10.57 ? 60  LEU B CD1 1 
ATOM   2241 C CD2 . LEU B 1 60  ? -18.582 14.819  -14.890 1.00 11.05 ? 60  LEU B CD2 1 
ATOM   2242 N N   . VAL B 1 61  ? -17.704 9.755   -16.937 1.00 10.38 ? 61  VAL B N   1 
ATOM   2243 C CA  . VAL B 1 61  ? -18.293 8.489   -17.378 1.00 10.59 ? 61  VAL B CA  1 
ATOM   2244 C C   . VAL B 1 61  ? -18.822 7.691   -16.184 1.00 10.86 ? 61  VAL B C   1 
ATOM   2245 O O   . VAL B 1 61  ? -19.969 7.233   -16.189 1.00 11.97 ? 61  VAL B O   1 
ATOM   2246 C CB  . VAL B 1 61  ? -17.279 7.678   -18.204 1.00 10.41 ? 61  VAL B CB  1 
ATOM   2247 C CG1 . VAL B 1 61  ? -17.755 6.232   -18.359 1.00 12.62 ? 61  VAL B CG1 1 
ATOM   2248 C CG2 . VAL B 1 61  ? -17.077 8.337   -19.611 1.00 8.34  ? 61  VAL B CG2 1 
ATOM   2249 N N   . THR B 1 62  ? -18.007 7.522   -15.132 1.00 9.96  ? 62  THR B N   1 
ATOM   2250 C CA  . THR B 1 62  ? -18.470 6.702   -14.004 1.00 11.77 ? 62  THR B CA  1 
ATOM   2251 C C   . THR B 1 62  ? -19.684 7.318   -13.313 1.00 10.53 ? 62  THR B C   1 
ATOM   2252 O O   . THR B 1 62  ? -20.529 6.590   -12.773 1.00 10.10 ? 62  THR B O   1 
ATOM   2253 C CB  . THR B 1 62  ? -17.362 6.490   -12.968 1.00 10.97 ? 62  THR B CB  1 
ATOM   2254 O OG1 . THR B 1 62  ? -16.734 7.745   -12.680 1.00 12.22 ? 62  THR B OG1 1 
ATOM   2255 C CG2 . THR B 1 62  ? -16.305 5.503   -13.475 1.00 9.65  ? 62  THR B CG2 1 
ATOM   2256 N N   . THR B 1 63  ? -19.798 8.648   -13.322 1.00 11.58 ? 63  THR B N   1 
ATOM   2257 C CA  . THR B 1 63  ? -20.962 9.273   -12.696 1.00 9.09  ? 63  THR B CA  1 
ATOM   2258 C C   . THR B 1 63  ? -22.217 9.068   -13.534 1.00 11.08 ? 63  THR B C   1 
ATOM   2259 O O   . THR B 1 63  ? -23.277 8.726   -12.995 1.00 11.01 ? 63  THR B O   1 
ATOM   2260 C CB  . THR B 1 63  ? -20.682 10.754  -12.466 1.00 11.02 ? 63  THR B CB  1 
ATOM   2261 O OG1 . THR B 1 63  ? -19.550 10.881  -11.584 1.00 10.17 ? 63  THR B OG1 1 
ATOM   2262 C CG2 . THR B 1 63  ? -21.897 11.463  -11.866 1.00 10.07 ? 63  THR B CG2 1 
ATOM   2263 N N   . LEU B 1 64  ? -22.109 9.240   -14.857 1.00 9.71  ? 64  LEU B N   1 
ATOM   2264 C CA  . LEU B 1 64  ? -23.252 9.114   -15.767 1.00 9.11  ? 64  LEU B CA  1 
ATOM   2265 C C   . LEU B 1 64  ? -23.759 7.679   -15.902 1.00 10.55 ? 64  LEU B C   1 
ATOM   2266 O O   . LEU B 1 64  ? -24.961 7.452   -15.999 1.00 9.79  ? 64  LEU B O   1 
ATOM   2267 C CB  . LEU B 1 64  ? -22.887 9.666   -17.142 1.00 10.40 ? 64  LEU B CB  1 
ATOM   2268 C CG  . LEU B 1 64  ? -22.491 11.146  -17.176 1.00 10.04 ? 64  LEU B CG  1 
ATOM   2269 C CD1 . LEU B 1 64  ? -21.861 11.519  -18.528 1.00 8.98  ? 64  LEU B CD1 1 
ATOM   2270 C CD2 . LEU B 1 64  ? -23.713 12.049  -16.930 1.00 12.97 ? 64  LEU B CD2 1 
HETATM 2271 N N1  . CRO B 1 65  ? -22.641 6.844   -15.993 1.00 17.99 ? 66  CRO B N1  1 
HETATM 2272 C CA1 . CRO B 1 65  ? -22.920 5.452   -16.099 1.00 20.90 ? 66  CRO B CA1 1 
HETATM 2273 C CB1 . CRO B 1 65  ? -22.663 4.824   -17.462 1.00 23.20 ? 66  CRO B CB1 1 
HETATM 2274 C CG1 . CRO B 1 65  ? -23.652 5.314   -18.485 1.00 24.40 ? 66  CRO B CG1 1 
HETATM 2275 O OG1 . CRO B 1 65  ? -21.591 4.863   -17.829 1.00 24.62 ? 66  CRO B OG1 1 
HETATM 2276 C C1  . CRO B 1 65  ? -22.384 4.613   -14.948 1.00 21.76 ? 66  CRO B C1  1 
HETATM 2277 N N2  . CRO B 1 65  ? -21.285 3.955   -15.021 1.00 22.47 ? 66  CRO B N2  1 
HETATM 2278 N N3  . CRO B 1 65  ? -22.804 4.581   -13.728 1.00 23.25 ? 66  CRO B N3  1 
HETATM 2279 C C2  . CRO B 1 65  ? -21.944 3.928   -13.030 1.00 21.79 ? 66  CRO B C2  1 
HETATM 2280 O O2  . CRO B 1 65  ? -22.019 3.704   -11.691 1.00 18.00 ? 66  CRO B O2  1 
HETATM 2281 C CA2 . CRO B 1 65  ? -20.960 3.515   -13.866 1.00 21.45 ? 66  CRO B CA2 1 
HETATM 2282 C CA3 . CRO B 1 65  ? -23.965 5.182   -13.170 1.00 20.45 ? 66  CRO B CA3 1 
HETATM 2283 C C3  . CRO B 1 65  ? -25.179 4.249   -13.073 1.00 23.06 ? 66  CRO B C3  1 
HETATM 2284 O O3  . CRO B 1 65  ? -26.029 4.613   -12.371 1.00 21.42 ? 66  CRO B O3  1 
HETATM 2285 C CB2 . CRO B 1 65  ? -19.797 2.645   -13.417 1.00 22.13 ? 66  CRO B CB2 1 
HETATM 2286 C CG2 . CRO B 1 65  ? -18.605 2.336   -14.295 1.00 23.78 ? 66  CRO B CG2 1 
HETATM 2287 C CD1 . CRO B 1 65  ? -18.465 2.618   -15.634 1.00 24.17 ? 66  CRO B CD1 1 
HETATM 2288 C CD2 . CRO B 1 65  ? -17.569 1.713   -13.663 1.00 25.01 ? 66  CRO B CD2 1 
HETATM 2289 C CE1 . CRO B 1 65  ? -17.320 2.268   -16.290 1.00 18.44 ? 66  CRO B CE1 1 
HETATM 2290 C CE2 . CRO B 1 65  ? -16.420 1.379   -14.295 1.00 21.78 ? 66  CRO B CE2 1 
HETATM 2291 C CZ  . CRO B 1 65  ? -16.296 1.647   -15.619 1.00 24.82 ? 66  CRO B CZ  1 
HETATM 2292 O OH  . CRO B 1 65  ? -15.134 1.294   -16.232 1.00 24.68 ? 66  CRO B OH  1 
ATOM   2293 N N   . VAL B 1 66  ? -25.172 3.346   -13.933 1.00 9.98  ? 68  VAL B N   1 
ATOM   2294 C CA  . VAL B 1 66  ? -26.389 2.561   -14.013 1.00 9.48  ? 68  VAL B CA  1 
ATOM   2295 C C   . VAL B 1 66  ? -25.996 1.091   -14.019 1.00 11.64 ? 68  VAL B C   1 
ATOM   2296 O O   . VAL B 1 66  ? -26.283 0.357   -14.953 1.00 13.44 ? 68  VAL B O   1 
ATOM   2297 C CB  . VAL B 1 66  ? -27.256 2.961   -15.240 1.00 11.21 ? 68  VAL B CB  1 
ATOM   2298 C CG1 . VAL B 1 66  ? -27.900 4.335   -15.003 1.00 12.02 ? 68  VAL B CG1 1 
ATOM   2299 C CG2 . VAL B 1 66  ? -26.415 2.993   -16.555 1.00 12.01 ? 68  VAL B CG2 1 
ATOM   2300 N N   . GLN B 1 67  ? -25.322 0.678   -12.943 1.00 12.02 ? 69  GLN B N   1 
ATOM   2301 C CA  . GLN B 1 67  ? -24.820 -0.688  -12.818 1.00 12.40 ? 69  GLN B CA  1 
ATOM   2302 C C   . GLN B 1 67  ? -25.935 -1.716  -12.722 1.00 13.02 ? 69  GLN B C   1 
ATOM   2303 O O   . GLN B 1 67  ? -25.651 -2.917  -12.815 1.00 15.53 ? 69  GLN B O   1 
ATOM   2304 C CB  . GLN B 1 67  ? -23.879 -0.798  -11.607 1.00 13.84 ? 69  GLN B CB  1 
ATOM   2305 C CG  . GLN B 1 67  ? -22.649 0.139   -11.743 1.00 16.33 ? 69  GLN B CG  1 
ATOM   2306 C CD  . GLN B 1 67  ? -21.877 0.342   -10.433 1.00 16.71 ? 69  GLN B CD  1 
ATOM   2307 O OE1 . GLN B 1 67  ? -22.458 0.724   -9.426  1.00 15.83 ? 69  GLN B OE1 1 
ATOM   2308 N NE2 . GLN B 1 67  ? -20.547 0.168   -10.474 1.00 15.79 ? 69  GLN B NE2 1 
ATOM   2309 N N   . CYS B 1 68  ? -27.189 -1.275  -12.578 1.00 14.68 ? 70  CYS B N   1 
ATOM   2310 C CA  . CYS B 1 68  ? -28.327 -2.185  -12.689 1.00 15.11 ? 70  CYS B CA  1 
ATOM   2311 C C   . CYS B 1 68  ? -28.435 -2.845  -14.057 1.00 15.05 ? 70  CYS B C   1 
ATOM   2312 O O   . CYS B 1 68  ? -29.173 -3.822  -14.196 1.00 17.10 ? 70  CYS B O   1 
ATOM   2313 C CB  . CYS B 1 68  ? -29.633 -1.446  -12.369 1.00 12.17 ? 70  CYS B CB  1 
ATOM   2314 S SG  . CYS B 1 68  ? -29.853 0.133   -13.227 1.00 15.70 ? 70  CYS B SG  1 
ATOM   2315 N N   . PHE B 1 69  ? -27.747 -2.345  -15.079 1.00 13.58 ? 71  PHE B N   1 
ATOM   2316 C CA  . PHE B 1 69  ? -27.849 -3.000  -16.374 1.00 14.37 ? 71  PHE B CA  1 
ATOM   2317 C C   . PHE B 1 69  ? -26.792 -4.070  -16.586 1.00 15.66 ? 71  PHE B C   1 
ATOM   2318 O O   . PHE B 1 69  ? -26.644 -4.558  -17.713 1.00 14.23 ? 71  PHE B O   1 
ATOM   2319 C CB  . PHE B 1 69  ? -27.796 -1.963  -17.496 1.00 15.01 ? 71  PHE B CB  1 
ATOM   2320 C CG  . PHE B 1 69  ? -29.078 -1.218  -17.628 1.00 13.87 ? 71  PHE B CG  1 
ATOM   2321 C CD1 . PHE B 1 69  ? -30.148 -1.792  -18.289 1.00 15.97 ? 71  PHE B CD1 1 
ATOM   2322 C CD2 . PHE B 1 69  ? -29.231 0.030   -17.052 1.00 12.54 ? 71  PHE B CD2 1 
ATOM   2323 C CE1 . PHE B 1 69  ? -31.365 -1.122  -18.382 1.00 16.74 ? 71  PHE B CE1 1 
ATOM   2324 C CE2 . PHE B 1 69  ? -30.432 0.705   -17.140 1.00 14.30 ? 71  PHE B CE2 1 
ATOM   2325 C CZ  . PHE B 1 69  ? -31.504 0.130   -17.811 1.00 12.77 ? 71  PHE B CZ  1 
ATOM   2326 N N   . SER B 1 70  ? -26.084 -4.473  -15.534 1.00 14.00 ? 72  SER B N   1 
ATOM   2327 C CA  . SER B 1 70  ? -25.060 -5.501  -15.693 1.00 15.28 ? 72  SER B CA  1 
ATOM   2328 C C   . SER B 1 70  ? -25.675 -6.844  -16.052 1.00 19.28 ? 72  SER B C   1 
ATOM   2329 O O   . SER B 1 70  ? -26.747 -7.211  -15.561 1.00 19.53 ? 72  SER B O   1 
ATOM   2330 C CB  . SER B 1 70  ? -24.238 -5.662  -14.416 1.00 19.97 ? 72  SER B CB  1 
ATOM   2331 O OG  . SER B 1 70  ? -23.294 -6.719  -14.591 1.00 27.51 ? 72  SER B OG  1 
ATOM   2332 N N   . ARG B 1 71  ? -24.976 -7.575  -16.917 1.00 17.26 ? 73  ARG B N   1 
ATOM   2333 C CA  . ARG B 1 71  ? -25.236 -8.994  -17.104 1.00 20.10 ? 73  ARG B CA  1 
ATOM   2334 C C   . ARG B 1 71  ? -24.828 -9.746  -15.838 1.00 22.35 ? 73  ARG B C   1 
ATOM   2335 O O   . ARG B 1 71  ? -23.754 -9.509  -15.283 1.00 22.74 ? 73  ARG B O   1 
ATOM   2336 C CB  . ARG B 1 71  ? -24.465 -9.485  -18.339 1.00 19.79 ? 73  ARG B CB  1 
ATOM   2337 C CG  . ARG B 1 71  ? -25.103 -10.653 -19.039 1.00 23.36 ? 73  ARG B CG  1 
ATOM   2338 C CD  . ARG B 1 71  ? -24.510 -10.953 -20.417 1.00 23.35 ? 73  ARG B CD  1 
ATOM   2339 N NE  . ARG B 1 71  ? -23.073 -11.199 -20.461 1.00 19.80 ? 73  ARG B NE  1 
ATOM   2340 C CZ  . ARG B 1 71  ? -22.543 -12.414 -20.516 1.00 26.29 ? 73  ARG B CZ  1 
ATOM   2341 N NH1 . ARG B 1 71  ? -23.275 -13.489 -20.274 1.00 20.46 ? 73  ARG B NH1 1 
ATOM   2342 N NH2 . ARG B 1 71  ? -21.248 -12.554 -20.813 1.00 20.24 ? 73  ARG B NH2 1 
ATOM   2343 N N   . TYR B 1 72  ? -25.712 -10.604 -15.337 1.00 23.93 ? 74  TYR B N   1 
ATOM   2344 C CA  . TYR B 1 72  ? -25.408 -11.401 -14.156 1.00 26.36 ? 74  TYR B CA  1 
ATOM   2345 C C   . TYR B 1 72  ? -25.611 -12.875 -14.490 1.00 28.13 ? 74  TYR B C   1 
ATOM   2346 O O   . TYR B 1 72  ? -26.482 -13.209 -15.298 1.00 29.22 ? 74  TYR B O   1 
ATOM   2347 C CB  . TYR B 1 72  ? -26.301 -11.016 -12.941 1.00 30.35 ? 74  TYR B CB  1 
ATOM   2348 C CG  . TYR B 1 72  ? -25.706 -9.974  -11.985 1.00 29.86 ? 74  TYR B CG  1 
ATOM   2349 C CD1 . TYR B 1 72  ? -25.764 -8.620  -12.282 1.00 25.81 ? 74  TYR B CD1 1 
ATOM   2350 C CD2 . TYR B 1 72  ? -25.100 -10.347 -10.791 1.00 33.24 ? 74  TYR B CD2 1 
ATOM   2351 C CE1 . TYR B 1 72  ? -25.232 -7.665  -11.431 1.00 27.29 ? 74  TYR B CE1 1 
ATOM   2352 C CE2 . TYR B 1 72  ? -24.557 -9.394  -9.923  1.00 31.25 ? 74  TYR B CE2 1 
ATOM   2353 C CZ  . TYR B 1 72  ? -24.627 -8.047  -10.254 1.00 32.88 ? 74  TYR B CZ  1 
ATOM   2354 O OH  . TYR B 1 72  ? -24.095 -7.066  -9.426  1.00 26.35 ? 74  TYR B OH  1 
ATOM   2355 N N   . PRO B 1 73  ? -24.848 -13.756 -13.885 1.00 32.23 ? 75  PRO B N   1 
ATOM   2356 C CA  . PRO B 1 73  ? -25.056 -15.176 -14.121 1.00 40.04 ? 75  PRO B CA  1 
ATOM   2357 C C   . PRO B 1 73  ? -26.259 -15.642 -13.376 1.00 44.20 ? 75  PRO B C   1 
ATOM   2358 O O   . PRO B 1 73  ? -26.614 -15.054 -12.410 1.00 44.88 ? 75  PRO B O   1 
ATOM   2359 C CB  . PRO B 1 73  ? -23.818 -15.835 -13.519 1.00 40.41 ? 75  PRO B CB  1 
ATOM   2360 C CG  . PRO B 1 73  ? -23.132 -14.859 -12.794 1.00 40.58 ? 75  PRO B CG  1 
ATOM   2361 C CD  . PRO B 1 73  ? -23.602 -13.510 -13.172 1.00 34.81 ? 75  PRO B CD  1 
ATOM   2362 N N   . ASP B 1 74  ? -26.882 -16.702 -13.813 1.00 47.17 ? 76  ASP B N   1 
ATOM   2363 C CA  . ASP B 1 74  ? -28.018 -17.202 -13.062 1.00 50.64 ? 76  ASP B CA  1 
ATOM   2364 C C   . ASP B 1 74  ? -27.755 -17.508 -11.569 1.00 53.63 ? 76  ASP B C   1 
ATOM   2365 O O   . ASP B 1 74  ? -28.576 -17.194 -10.744 1.00 54.16 ? 76  ASP B O   1 
ATOM   2366 C CB  . ASP B 1 74  ? -28.636 -18.395 -13.758 1.00 49.41 ? 76  ASP B CB  1 
ATOM   2367 C CG  . ASP B 1 74  ? -29.235 -18.036 -15.074 1.00 53.57 ? 76  ASP B CG  1 
ATOM   2368 O OD1 . ASP B 1 74  ? -29.412 -16.858 -15.354 1.00 58.08 ? 76  ASP B OD1 1 
ATOM   2369 O OD2 . ASP B 1 74  ? -29.543 -18.938 -15.853 1.00 61.03 ? 76  ASP B OD2 1 
ATOM   2370 N N   . HIS B 1 75  ? -26.642 -18.126 -11.216 1.00 55.70 ? 77  HIS B N   1 
ATOM   2371 C CA  . HIS B 1 75  ? -26.433 -18.477 -9.805  1.00 59.87 ? 77  HIS B CA  1 
ATOM   2372 C C   . HIS B 1 75  ? -26.324 -17.250 -8.983  1.00 58.93 ? 77  HIS B C   1 
ATOM   2373 O O   . HIS B 1 75  ? -26.494 -17.266 -7.800  1.00 64.75 ? 77  HIS B O   1 
ATOM   2374 C CB  . HIS B 1 75  ? -25.191 -19.334 -9.567  1.00 63.96 ? 77  HIS B CB  1 
ATOM   2375 C CG  . HIS B 1 75  ? -24.136 -19.161 -10.608 1.00 64.25 ? 77  HIS B CG  1 
ATOM   2376 N ND1 . HIS B 1 75  ? -24.352 -19.458 -11.935 1.00 63.67 ? 77  HIS B ND1 1 
ATOM   2377 C CD2 . HIS B 1 75  ? -22.870 -18.694 -10.522 1.00 65.27 ? 77  HIS B CD2 1 
ATOM   2378 C CE1 . HIS B 1 75  ? -23.265 -19.171 -12.622 1.00 65.73 ? 77  HIS B CE1 1 
ATOM   2379 N NE2 . HIS B 1 75  ? -22.342 -18.729 -11.786 1.00 66.18 ? 77  HIS B NE2 1 
ATOM   2380 N N   . MET B 1 76  ? -26.076 -16.139 -9.638  1.00 57.17 ? 78  MET B N   1 
ATOM   2381 C CA  . MET B 1 76  ? -25.835 -14.908 -8.957  1.00 54.84 ? 78  MET B CA  1 
ATOM   2382 C C   . MET B 1 76  ? -27.010 -13.948 -9.021  1.00 54.45 ? 78  MET B C   1 
ATOM   2383 O O   . MET B 1 76  ? -26.990 -12.921 -8.397  1.00 52.81 ? 78  MET B O   1 
ATOM   2384 C CB  . MET B 1 76  ? -24.585 -14.261 -9.558  1.00 53.90 ? 78  MET B CB  1 
ATOM   2385 C CG  . MET B 1 76  ? -23.827 -13.344 -8.616  1.00 53.66 ? 78  MET B CG  1 
ATOM   2386 S SD  . MET B 1 76  ? -22.138 -13.186 -9.109  1.00 51.78 ? 78  MET B SD  1 
ATOM   2387 C CE  . MET B 1 76  ? -21.769 -14.895 -9.206  1.00 51.02 ? 78  MET B CE  1 
ATOM   2388 N N   . LYS B 1 77  ? -28.026 -14.292 -9.783  1.00 56.78 ? 79  LYS B N   1 
ATOM   2389 C CA  . LYS B 1 77  ? -29.133 -13.395 -10.013 1.00 53.45 ? 79  LYS B CA  1 
ATOM   2390 C C   . LYS B 1 77  ? -29.892 -13.402 -8.757  1.00 56.89 ? 79  LYS B C   1 
ATOM   2391 O O   . LYS B 1 77  ? -31.097 -13.513 -8.723  1.00 63.27 ? 79  LYS B O   1 
ATOM   2392 C CB  . LYS B 1 77  ? -30.002 -13.808 -11.207 1.00 51.33 ? 79  LYS B CB  1 
ATOM   2393 C CG  . LYS B 1 77  ? -29.462 -13.417 -12.568 1.00 49.87 ? 79  LYS B CG  1 
ATOM   2394 C CD  . LYS B 1 77  ? -30.037 -14.275 -13.678 1.00 50.38 ? 79  LYS B CD  1 
ATOM   2395 C CE  . LYS B 1 77  ? -29.702 -13.728 -15.054 1.00 49.99 ? 79  LYS B CE  1 
ATOM   2396 N NZ  . LYS B 1 77  ? -30.877 -13.912 -15.954 1.00 57.89 ? 79  LYS B NZ  1 
ATOM   2397 N N   . ARG B 1 78  ? -29.166 -13.300 -7.678  1.00 55.66 ? 80  ARG B N   1 
ATOM   2398 C CA  . ARG B 1 78  ? -29.830 -13.201 -6.406  1.00 60.89 ? 80  ARG B CA  1 
ATOM   2399 C C   . ARG B 1 78  ? -28.895 -12.348 -5.693  1.00 57.93 ? 80  ARG B C   1 
ATOM   2400 O O   . ARG B 1 78  ? -29.176 -11.812 -4.649  1.00 54.34 ? 80  ARG B O   1 
ATOM   2401 C CB  . ARG B 1 78  ? -29.950 -14.541 -5.742  1.00 61.03 ? 80  ARG B CB  1 
ATOM   2402 C CG  . ARG B 1 78  ? -28.779 -14.914 -4.977  1.00 63.93 ? 80  ARG B CG  1 
ATOM   2403 C CD  . ARG B 1 78  ? -28.259 -16.139 -5.605  1.00 66.62 ? 80  ARG B CD  1 
ATOM   2404 N NE  . ARG B 1 78  ? -29.202 -17.254 -5.485  1.00 70.97 ? 80  ARG B NE  1 
ATOM   2405 C CZ  . ARG B 1 78  ? -28.840 -18.444 -5.034  1.00 72.56 ? 80  ARG B CZ  1 
ATOM   2406 N NH1 . ARG B 1 78  ? -27.585 -18.629 -4.688  1.00 73.42 ? 80  ARG B NH1 1 
ATOM   2407 N NH2 . ARG B 1 78  ? -29.721 -19.431 -4.924  1.00 71.10 ? 80  ARG B NH2 1 
ATOM   2408 N N   . HIS B 1 79  ? -27.731 -12.221 -6.294  1.00 56.12 ? 81  HIS B N   1 
ATOM   2409 C CA  . HIS B 1 79  ? -26.724 -11.311 -5.786  1.00 52.80 ? 81  HIS B CA  1 
ATOM   2410 C C   . HIS B 1 79  ? -26.970 -9.916  -6.301  1.00 46.29 ? 81  HIS B C   1 
ATOM   2411 O O   . HIS B 1 79  ? -26.144 -9.069  -6.095  1.00 47.52 ? 81  HIS B O   1 
ATOM   2412 C CB  . HIS B 1 79  ? -25.333 -11.793 -6.184  1.00 49.00 ? 81  HIS B CB  1 
ATOM   2413 C CG  . HIS B 1 79  ? -24.947 -13.045 -5.474  1.00 56.13 ? 81  HIS B CG  1 
ATOM   2414 N ND1 . HIS B 1 79  ? -24.394 -13.034 -4.224  1.00 56.36 ? 81  HIS B ND1 1 
ATOM   2415 C CD2 . HIS B 1 79  ? -25.151 -14.345 -5.780  1.00 62.69 ? 81  HIS B CD2 1 
ATOM   2416 C CE1 . HIS B 1 79  ? -24.245 -14.273 -3.795  1.00 60.18 ? 81  HIS B CE1 1 
ATOM   2417 N NE2 . HIS B 1 79  ? -24.690 -15.089 -4.730  1.00 62.57 ? 81  HIS B NE2 1 
ATOM   2418 N N   . ASP B 1 80  ? -28.084 -9.681  -6.982  1.00 42.67 ? 82  ASP B N   1 
ATOM   2419 C CA  . ASP B 1 80  ? -28.252 -8.439  -7.729  1.00 32.36 ? 82  ASP B CA  1 
ATOM   2420 C C   . ASP B 1 80  ? -28.974 -7.348  -7.022  1.00 29.96 ? 82  ASP B C   1 
ATOM   2421 O O   . ASP B 1 80  ? -30.116 -7.086  -7.287  1.00 29.03 ? 82  ASP B O   1 
ATOM   2422 C CB  . ASP B 1 80  ? -28.880 -8.676  -9.096  1.00 29.78 ? 82  ASP B CB  1 
ATOM   2423 C CG  . ASP B 1 80  ? -28.512 -7.612  -10.082 1.00 24.85 ? 82  ASP B CG  1 
ATOM   2424 O OD1 . ASP B 1 80  ? -28.156 -6.547  -9.660  1.00 28.60 ? 82  ASP B OD1 1 
ATOM   2425 O OD2 . ASP B 1 80  ? -28.616 -7.845  -11.255 1.00 26.85 ? 82  ASP B OD2 1 
ATOM   2426 N N   . PHE B 1 81  ? -28.250 -6.706  -6.132  1.00 24.96 ? 83  PHE B N   1 
ATOM   2427 C CA  . PHE B 1 81  ? -28.792 -5.591  -5.368  1.00 20.48 ? 83  PHE B CA  1 
ATOM   2428 C C   . PHE B 1 81  ? -29.333 -4.507  -6.290  1.00 20.72 ? 83  PHE B C   1 
ATOM   2429 O O   . PHE B 1 81  ? -30.399 -3.936  -6.034  1.00 18.41 ? 83  PHE B O   1 
ATOM   2430 C CB  . PHE B 1 81  ? -27.706 -5.010  -4.457  1.00 21.31 ? 83  PHE B CB  1 
ATOM   2431 C CG  . PHE B 1 81  ? -27.985 -3.596  -4.009  1.00 22.79 ? 83  PHE B CG  1 
ATOM   2432 C CD1 . PHE B 1 81  ? -28.721 -3.361  -2.857  1.00 23.19 ? 83  PHE B CD1 1 
ATOM   2433 C CD2 . PHE B 1 81  ? -27.542 -2.506  -4.758  1.00 18.94 ? 83  PHE B CD2 1 
ATOM   2434 C CE1 . PHE B 1 81  ? -28.993 -2.068  -2.448  1.00 22.28 ? 83  PHE B CE1 1 
ATOM   2435 C CE2 . PHE B 1 81  ? -27.818 -1.210  -4.370  1.00 18.55 ? 83  PHE B CE2 1 
ATOM   2436 C CZ  . PHE B 1 81  ? -28.540 -0.981  -3.209  1.00 23.74 ? 83  PHE B CZ  1 
ATOM   2437 N N   . PHE B 1 82  ? -28.607 -4.206  -7.372  1.00 17.36 ? 84  PHE B N   1 
ATOM   2438 C CA  . PHE B 1 82  ? -28.963 -3.057  -8.206  1.00 18.26 ? 84  PHE B CA  1 
ATOM   2439 C C   . PHE B 1 82  ? -30.337 -3.232  -8.846  1.00 16.96 ? 84  PHE B C   1 
ATOM   2440 O O   . PHE B 1 82  ? -31.125 -2.282  -8.899  1.00 16.25 ? 84  PHE B O   1 
ATOM   2441 C CB  . PHE B 1 82  ? -27.906 -2.841  -9.289  1.00 16.06 ? 84  PHE B CB  1 
ATOM   2442 C CG  . PHE B 1 82  ? -26.515 -2.599  -8.759  1.00 15.42 ? 84  PHE B CG  1 
ATOM   2443 C CD1 . PHE B 1 82  ? -26.172 -1.380  -8.208  1.00 17.86 ? 84  PHE B CD1 1 
ATOM   2444 C CD2 . PHE B 1 82  ? -25.549 -3.592  -8.833  1.00 18.02 ? 84  PHE B CD2 1 
ATOM   2445 C CE1 . PHE B 1 82  ? -24.882 -1.144  -7.735  1.00 19.45 ? 84  PHE B CE1 1 
ATOM   2446 C CE2 . PHE B 1 82  ? -24.255 -3.364  -8.364  1.00 17.64 ? 84  PHE B CE2 1 
ATOM   2447 C CZ  . PHE B 1 82  ? -23.929 -2.132  -7.809  1.00 15.87 ? 84  PHE B CZ  1 
ATOM   2448 N N   . LYS B 1 83  ? -30.630 -4.428  -9.367  1.00 16.86 ? 85  LYS B N   1 
ATOM   2449 C CA  . LYS B 1 83  ? -31.940 -4.686  -9.967  1.00 18.53 ? 85  LYS B CA  1 
ATOM   2450 C C   . LYS B 1 83  ? -33.023 -4.921  -8.919  1.00 21.87 ? 85  LYS B C   1 
ATOM   2451 O O   . LYS B 1 83  ? -34.162 -4.470  -9.088  1.00 19.44 ? 85  LYS B O   1 
ATOM   2452 C CB  . LYS B 1 83  ? -31.874 -5.883  -10.924 1.00 18.74 ? 85  LYS B CB  1 
ATOM   2453 C CG  . LYS B 1 83  ? -31.032 -5.665  -12.175 1.00 18.77 ? 85  LYS B CG  1 
ATOM   2454 C CD  . LYS B 1 83  ? -31.128 -6.865  -13.134 1.00 20.21 ? 85  LYS B CD  1 
ATOM   2455 C CE  . LYS B 1 83  ? -30.062 -6.804  -14.230 1.00 15.83 ? 85  LYS B CE  1 
ATOM   2456 N NZ  . LYS B 1 83  ? -28.692 -6.572  -13.713 1.00 19.02 ? 85  LYS B NZ  1 
ATOM   2457 N N   . SER B 1 84  ? -32.697 -5.620  -7.834  1.00 19.16 ? 86  SER B N   1 
ATOM   2458 C CA  . SER B 1 84  ? -33.712 -5.924  -6.833  1.00 24.55 ? 86  SER B CA  1 
ATOM   2459 C C   . SER B 1 84  ? -34.190 -4.683  -6.083  1.00 23.43 ? 86  SER B C   1 
ATOM   2460 O O   . SER B 1 84  ? -35.285 -4.702  -5.506  1.00 22.95 ? 86  SER B O   1 
ATOM   2461 C CB  . SER B 1 84  ? -33.166 -6.969  -5.862  1.00 30.42 ? 86  SER B CB  1 
ATOM   2462 O OG  . SER B 1 84  ? -32.670 -6.338  -4.695  1.00 36.72 ? 86  SER B OG  1 
ATOM   2463 N N   . ALA B 1 85  ? -33.400 -3.610  -6.083  1.00 19.44 ? 87  ALA B N   1 
ATOM   2464 C CA  . ALA B 1 85  ? -33.833 -2.347  -5.504  1.00 20.78 ? 87  ALA B CA  1 
ATOM   2465 C C   . ALA B 1 85  ? -34.917 -1.661  -6.333  1.00 20.93 ? 87  ALA B C   1 
ATOM   2466 O O   . ALA B 1 85  ? -35.589 -0.756  -5.820  1.00 19.61 ? 87  ALA B O   1 
ATOM   2467 C CB  . ALA B 1 85  ? -32.624 -1.419  -5.338  1.00 18.93 ? 87  ALA B CB  1 
ATOM   2468 N N   . MET B 1 86  ? -35.110 -2.081  -7.580  1.00 17.81 ? 88  MET B N   1 
ATOM   2469 C CA  . MET B 1 86  ? -36.036 -1.497  -8.533  1.00 18.03 ? 88  MET B CA  1 
ATOM   2470 C C   . MET B 1 86  ? -37.464 -1.976  -8.230  1.00 20.12 ? 88  MET B C   1 
ATOM   2471 O O   . MET B 1 86  ? -37.654 -3.071  -7.691  1.00 20.90 ? 88  MET B O   1 
ATOM   2472 C CB  . MET B 1 86  ? -35.620 -1.911  -9.942  1.00 19.49 ? 88  MET B CB  1 
ATOM   2473 C CG  . MET B 1 86  ? -34.476 -1.089  -10.573 1.00 17.92 ? 88  MET B CG  1 
ATOM   2474 S SD  . MET B 1 86  ? -34.312 0.648   -10.082 1.00 16.10 ? 88  MET B SD  1 
ATOM   2475 C CE  . MET B 1 86  ? -32.518 0.823   -9.981  1.00 15.85 ? 88  MET B CE  1 
ATOM   2476 N N   . PRO B 1 87  ? -38.497 -1.168  -8.546  1.00 21.63 ? 89  PRO B N   1 
ATOM   2477 C CA  . PRO B 1 87  ? -38.516 0.149   -9.195  1.00 19.33 ? 89  PRO B CA  1 
ATOM   2478 C C   . PRO B 1 87  ? -38.226 1.334   -8.278  1.00 19.44 ? 89  PRO B C   1 
ATOM   2479 O O   . PRO B 1 87  ? -37.935 2.411   -8.803  1.00 18.54 ? 89  PRO B O   1 
ATOM   2480 C CB  . PRO B 1 87  ? -39.952 0.260   -9.719  1.00 19.78 ? 89  PRO B CB  1 
ATOM   2481 C CG  . PRO B 1 87  ? -40.749 -0.529  -8.733  1.00 21.64 ? 89  PRO B CG  1 
ATOM   2482 C CD  . PRO B 1 87  ? -39.860 -1.703  -8.369  1.00 22.57 ? 89  PRO B CD  1 
ATOM   2483 N N   . GLU B 1 88  ? -38.319 1.155   -6.953  1.00 19.07 ? 90  GLU B N   1 
ATOM   2484 C CA  . GLU B 1 88  ? -38.126 2.292   -6.055  1.00 20.87 ? 90  GLU B CA  1 
ATOM   2485 C C   . GLU B 1 88  ? -36.722 2.873   -6.202  1.00 19.93 ? 90  GLU B C   1 
ATOM   2486 O O   . GLU B 1 88  ? -36.532 4.092   -6.121  1.00 16.99 ? 90  GLU B O   1 
ATOM   2487 C CB  . GLU B 1 88  ? -38.402 1.885   -4.604  1.00 20.85 ? 90  GLU B CB  1 
ATOM   2488 C CG  . GLU B 1 88  ? -39.807 1.303   -4.400  1.00 23.52 ? 90  GLU B CG  1 
ATOM   2489 C CD  . GLU B 1 88  ? -39.852 -0.218  -4.472  1.00 30.67 ? 90  GLU B CD  1 
ATOM   2490 O OE1 . GLU B 1 88  ? -39.215 -0.807  -5.373  1.00 24.84 ? 90  GLU B OE1 1 
ATOM   2491 O OE2 . GLU B 1 88  ? -40.567 -0.829  -3.643  1.00 38.71 ? 90  GLU B OE2 1 
ATOM   2492 N N   . GLY B 1 89  ? -35.730 2.022   -6.416  1.00 19.56 ? 91  GLY B N   1 
ATOM   2493 C CA  . GLY B 1 89  ? -34.415 2.491   -6.809  1.00 18.96 ? 91  GLY B CA  1 
ATOM   2494 C C   . GLY B 1 89  ? -33.410 2.526   -5.674  1.00 17.48 ? 91  GLY B C   1 
ATOM   2495 O O   . GLY B 1 89  ? -33.603 1.962   -4.594  1.00 17.33 ? 91  GLY B O   1 
ATOM   2496 N N   . TYR B 1 90  ? -32.292 3.198   -5.945  1.00 14.65 ? 92  TYR B N   1 
ATOM   2497 C CA  . TYR B 1 90  ? -31.217 3.299   -4.969  1.00 15.45 ? 92  TYR B CA  1 
ATOM   2498 C C   . TYR B 1 90  ? -30.532 4.655   -5.081  1.00 16.84 ? 92  TYR B C   1 
ATOM   2499 O O   . TYR B 1 90  ? -30.563 5.316   -6.128  1.00 16.59 ? 92  TYR B O   1 
ATOM   2500 C CB  . TYR B 1 90  ? -30.192 2.159   -5.126  1.00 15.32 ? 92  TYR B CB  1 
ATOM   2501 C CG  . TYR B 1 90  ? -29.552 1.986   -6.502  1.00 17.77 ? 92  TYR B CG  1 
ATOM   2502 C CD1 . TYR B 1 90  ? -28.490 2.795   -6.915  1.00 14.21 ? 92  TYR B CD1 1 
ATOM   2503 C CD2 . TYR B 1 90  ? -29.978 0.978   -7.360  1.00 15.65 ? 92  TYR B CD2 1 
ATOM   2504 C CE1 . TYR B 1 90  ? -27.883 2.610   -8.180  1.00 13.69 ? 92  TYR B CE1 1 
ATOM   2505 C CE2 . TYR B 1 90  ? -29.379 0.782   -8.610  1.00 16.74 ? 92  TYR B CE2 1 
ATOM   2506 C CZ  . TYR B 1 90  ? -28.343 1.610   -9.007  1.00 14.87 ? 92  TYR B CZ  1 
ATOM   2507 O OH  . TYR B 1 90  ? -27.764 1.399   -10.231 1.00 16.00 ? 92  TYR B OH  1 
ATOM   2508 N N   . VAL B 1 91  ? -29.922 5.070   -3.973  1.00 14.70 ? 93  VAL B N   1 
ATOM   2509 C CA  . VAL B 1 91  ? -29.082 6.260   -3.943  1.00 15.19 ? 93  VAL B CA  1 
ATOM   2510 C C   . VAL B 1 91  ? -27.645 5.819   -4.204  1.00 14.74 ? 93  VAL B C   1 
ATOM   2511 O O   . VAL B 1 91  ? -27.177 4.842   -3.617  1.00 13.78 ? 93  VAL B O   1 
ATOM   2512 C CB  . VAL B 1 91  ? -29.204 6.985   -2.591  1.00 18.13 ? 93  VAL B CB  1 
ATOM   2513 C CG1 . VAL B 1 91  ? -28.163 8.112   -2.486  1.00 17.61 ? 93  VAL B CG1 1 
ATOM   2514 C CG2 . VAL B 1 91  ? -30.625 7.516   -2.388  1.00 17.24 ? 93  VAL B CG2 1 
ATOM   2515 N N   . GLN B 1 92  ? -26.947 6.516   -5.098  1.00 13.40 ? 94  GLN B N   1 
ATOM   2516 C CA  . GLN B 1 92  ? -25.545 6.220   -5.387  1.00 10.60 ? 94  GLN B CA  1 
ATOM   2517 C C   . GLN B 1 92  ? -24.719 7.458   -5.075  1.00 11.76 ? 94  GLN B C   1 
ATOM   2518 O O   . GLN B 1 92  ? -24.919 8.507   -5.695  1.00 14.24 ? 94  GLN B O   1 
ATOM   2519 C CB  . GLN B 1 92  ? -25.349 5.787   -6.851  1.00 13.12 ? 94  GLN B CB  1 
ATOM   2520 C CG  . GLN B 1 92  ? -23.881 5.499   -7.217  1.00 11.40 ? 94  GLN B CG  1 
ATOM   2521 C CD  . GLN B 1 92  ? -23.719 4.625   -8.461  1.00 11.77 ? 94  GLN B CD  1 
ATOM   2522 O OE1 . GLN B 1 92  ? -24.258 3.519   -8.528  1.00 15.31 ? 94  GLN B OE1 1 
ATOM   2523 N NE2 . GLN B 1 92  ? -22.941 5.101   -9.432  1.00 10.47 ? 94  GLN B NE2 1 
ATOM   2524 N N   . GLU B 1 93  ? -23.811 7.349   -4.108  1.00 13.48 ? 95  GLU B N   1 
ATOM   2525 C CA  . GLU B 1 93  ? -22.954 8.464   -3.724  1.00 14.02 ? 95  GLU B CA  1 
ATOM   2526 C C   . GLU B 1 93  ? -21.502 8.123   -3.995  1.00 14.92 ? 95  GLU B C   1 
ATOM   2527 O O   . GLU B 1 93  ? -21.066 6.998   -3.735  1.00 13.38 ? 95  GLU B O   1 
ATOM   2528 C CB  . GLU B 1 93  ? -23.127 8.835   -2.239  1.00 17.40 ? 95  GLU B CB  1 
ATOM   2529 C CG  . GLU B 1 93  ? -24.504 9.385   -1.927  1.00 16.40 ? 95  GLU B CG  1 
ATOM   2530 C CD  . GLU B 1 93  ? -24.733 9.659   -0.454  1.00 31.11 ? 95  GLU B CD  1 
ATOM   2531 O OE1 . GLU B 1 93  ? -24.226 8.892   0.389   1.00 32.37 ? 95  GLU B OE1 1 
ATOM   2532 O OE2 . GLU B 1 93  ? -25.403 10.668  -0.149  1.00 32.36 ? 95  GLU B OE2 1 
ATOM   2533 N N   . ARG B 1 94  ? -20.749 9.102   -4.508  1.00 12.85 ? 96  ARG B N   1 
ATOM   2534 C CA  . ARG B 1 94  ? -19.328 8.884   -4.710  1.00 12.06 ? 96  ARG B CA  1 
ATOM   2535 C C   . ARG B 1 94  ? -18.534 10.092  -4.253  1.00 10.46 ? 96  ARG B C   1 
ATOM   2536 O O   . ARG B 1 94  ? -19.024 11.222  -4.257  1.00 11.22 ? 96  ARG B O   1 
ATOM   2537 C CB  . ARG B 1 94  ? -18.994 8.590   -6.187  1.00 11.40 ? 96  ARG B CB  1 
ATOM   2538 C CG  . ARG B 1 94  ? -19.475 7.195   -6.651  1.00 10.23 ? 96  ARG B CG  1 
ATOM   2539 C CD  . ARG B 1 94  ? -18.469 6.640   -7.661  1.00 11.70 ? 96  ARG B CD  1 
ATOM   2540 N NE  . ARG B 1 94  ? -18.883 5.387   -8.276  1.00 9.80  ? 96  ARG B NE  1 
ATOM   2541 C CZ  . ARG B 1 94  ? -19.557 5.308   -9.417  1.00 10.24 ? 96  ARG B CZ  1 
ATOM   2542 N NH1 . ARG B 1 94  ? -20.012 6.390   -10.030 1.00 10.02 ? 96  ARG B NH1 1 
ATOM   2543 N NH2 . ARG B 1 94  ? -19.798 4.115   -9.943  1.00 10.03 ? 96  ARG B NH2 1 
ATOM   2544 N N   . THR B 1 95  ? -17.285 9.835   -3.903  1.00 12.12 ? 97  THR B N   1 
ATOM   2545 C CA  . THR B 1 95  ? -16.235 10.840  -3.838  1.00 13.99 ? 97  THR B CA  1 
ATOM   2546 C C   . THR B 1 95  ? -15.114 10.388  -4.752  1.00 12.61 ? 97  THR B C   1 
ATOM   2547 O O   . THR B 1 95  ? -14.705 9.227   -4.694  1.00 12.92 ? 97  THR B O   1 
ATOM   2548 C CB  . THR B 1 95  ? -15.728 11.020  -2.401  1.00 17.06 ? 97  THR B CB  1 
ATOM   2549 O OG1 . THR B 1 95  ? -16.853 11.321  -1.563  1.00 15.62 ? 97  THR B OG1 1 
ATOM   2550 C CG2 . THR B 1 95  ? -14.686 12.141  -2.321  1.00 16.18 ? 97  THR B CG2 1 
ATOM   2551 N N   . ILE B 1 96  ? -14.648 11.286  -5.613  1.00 14.06 ? 98  ILE B N   1 
ATOM   2552 C CA  . ILE B 1 96  ? -13.671 10.952  -6.645  1.00 12.65 ? 98  ILE B CA  1 
ATOM   2553 C C   . ILE B 1 96  ? -12.531 11.954  -6.531  1.00 11.98 ? 98  ILE B C   1 
ATOM   2554 O O   . ILE B 1 96  ? -12.744 13.158  -6.711  1.00 13.12 ? 98  ILE B O   1 
ATOM   2555 C CB  . ILE B 1 96  ? -14.270 10.985  -8.066  1.00 13.19 ? 98  ILE B CB  1 
ATOM   2556 C CG1 . ILE B 1 96  ? -15.532 10.117  -8.174  1.00 11.81 ? 98  ILE B CG1 1 
ATOM   2557 C CG2 . ILE B 1 96  ? -13.254 10.510  -9.068  1.00 11.69 ? 98  ILE B CG2 1 
ATOM   2558 C CD1 . ILE B 1 96  ? -16.298 10.329  -9.543  1.00 11.17 ? 98  ILE B CD1 1 
ATOM   2559 N N   . PHE B 1 97  ? -11.338 11.465  -6.210  1.00 14.24 ? 99  PHE B N   1 
ATOM   2560 C CA  . PHE B 1 97  ? -10.164 12.307  -6.023  1.00 15.62 ? 99  PHE B CA  1 
ATOM   2561 C C   . PHE B 1 97  ? -9.312  12.237  -7.283  1.00 14.04 ? 99  PHE B C   1 
ATOM   2562 O O   . PHE B 1 97  ? -8.839  11.160  -7.649  1.00 12.09 ? 99  PHE B O   1 
ATOM   2563 C CB  . PHE B 1 97  ? -9.339  11.838  -4.822  1.00 16.42 ? 99  PHE B CB  1 
ATOM   2564 C CG  . PHE B 1 97  ? -10.030 11.999  -3.494  1.00 13.95 ? 99  PHE B CG  1 
ATOM   2565 C CD1 . PHE B 1 97  ? -10.036 13.226  -2.841  1.00 15.79 ? 99  PHE B CD1 1 
ATOM   2566 C CD2 . PHE B 1 97  ? -10.658 10.919  -2.891  1.00 16.76 ? 99  PHE B CD2 1 
ATOM   2567 C CE1 . PHE B 1 97  ? -10.658 13.372  -1.611  1.00 16.36 ? 99  PHE B CE1 1 
ATOM   2568 C CE2 . PHE B 1 97  ? -11.287 11.058  -1.651  1.00 14.33 ? 99  PHE B CE2 1 
ATOM   2569 C CZ  . PHE B 1 97  ? -11.284 12.287  -1.016  1.00 13.48 ? 99  PHE B CZ  1 
ATOM   2570 N N   . PHE B 1 98  ? -9.080  13.380  -7.916  1.00 12.87 ? 100 PHE B N   1 
ATOM   2571 C CA  . PHE B 1 98  ? -8.172  13.442  -9.052  1.00 14.02 ? 100 PHE B CA  1 
ATOM   2572 C C   . PHE B 1 98  ? -6.789  13.796  -8.529  1.00 16.76 ? 100 PHE B C   1 
ATOM   2573 O O   . PHE B 1 98  ? -6.591  14.873  -7.956  1.00 16.83 ? 100 PHE B O   1 
ATOM   2574 C CB  . PHE B 1 98  ? -8.651  14.449  -10.091 1.00 12.75 ? 100 PHE B CB  1 
ATOM   2575 C CG  . PHE B 1 98  ? -9.934  14.042  -10.762 1.00 14.54 ? 100 PHE B CG  1 
ATOM   2576 C CD1 . PHE B 1 98  ? -9.918  13.204  -11.859 1.00 14.16 ? 100 PHE B CD1 1 
ATOM   2577 C CD2 . PHE B 1 98  ? -11.155 14.460  -10.265 1.00 13.57 ? 100 PHE B CD2 1 
ATOM   2578 C CE1 . PHE B 1 98  ? -11.099 12.816  -12.471 1.00 17.40 ? 100 PHE B CE1 1 
ATOM   2579 C CE2 . PHE B 1 98  ? -12.336 14.067  -10.866 1.00 16.87 ? 100 PHE B CE2 1 
ATOM   2580 C CZ  . PHE B 1 98  ? -12.306 13.248  -11.976 1.00 13.59 ? 100 PHE B CZ  1 
ATOM   2581 N N   . LYS B 1 99  ? -5.854  12.873  -8.704  1.00 16.54 ? 101 LYS B N   1 
ATOM   2582 C CA  . LYS B 1 99  ? -4.533  12.987  -8.102  1.00 21.22 ? 101 LYS B CA  1 
ATOM   2583 C C   . LYS B 1 99  ? -3.867  14.308  -8.494  1.00 18.16 ? 101 LYS B C   1 
ATOM   2584 O O   . LYS B 1 99  ? -3.855  14.689  -9.665  1.00 19.40 ? 101 LYS B O   1 
ATOM   2585 C CB  . LYS B 1 99  ? -3.706  11.772  -8.537  1.00 19.89 ? 101 LYS B CB  1 
ATOM   2586 C CG  . LYS B 1 99  ? -2.456  11.449  -7.733  1.00 27.82 ? 101 LYS B CG  1 
ATOM   2587 C CD  . LYS B 1 99  ? -1.270  12.161  -8.316  1.00 31.69 ? 101 LYS B CD  1 
ATOM   2588 C CE  . LYS B 1 99  ? 0.014   11.385  -8.047  1.00 35.55 ? 101 LYS B CE  1 
ATOM   2589 N NZ  . LYS B 1 99  ? 0.088   10.957  -6.634  1.00 38.38 ? 101 LYS B NZ  1 
ATOM   2590 N N   . ASP B 1 100 ? -3.351  15.017  -7.483  1.00 18.85 ? 102 ASP B N   1 
ATOM   2591 C CA  . ASP B 1 100 ? -2.751  16.352  -7.616  1.00 20.29 ? 102 ASP B CA  1 
ATOM   2592 C C   . ASP B 1 100 ? -3.697  17.364  -8.253  1.00 21.06 ? 102 ASP B C   1 
ATOM   2593 O O   . ASP B 1 100 ? -3.255  18.323  -8.900  1.00 16.53 ? 102 ASP B O   1 
ATOM   2594 C CB  . ASP B 1 100 ? -1.432  16.317  -8.392  1.00 23.66 ? 102 ASP B CB  1 
ATOM   2595 C CG  . ASP B 1 100 ? -0.411  15.408  -7.758  1.00 24.64 ? 102 ASP B CG  1 
ATOM   2596 O OD1 . ASP B 1 100 ? -0.267  15.454  -6.525  1.00 29.70 ? 102 ASP B OD1 1 
ATOM   2597 O OD2 . ASP B 1 100 ? 0.311   14.715  -8.501  1.00 33.31 ? 102 ASP B OD2 1 
ATOM   2598 N N   . ASP B 1 101 ? -5.000  17.182  -8.057  1.00 15.90 ? 103 ASP B N   1 
ATOM   2599 C CA  . ASP B 1 101 ? -5.997  18.146  -8.518  1.00 19.75 ? 103 ASP B CA  1 
ATOM   2600 C C   . ASP B 1 101 ? -7.187  18.068  -7.560  1.00 16.89 ? 103 ASP B C   1 
ATOM   2601 O O   . ASP B 1 101 ? -7.054  17.581  -6.434  1.00 17.69 ? 103 ASP B O   1 
ATOM   2602 C CB  . ASP B 1 101 ? -6.388  17.867  -9.982  1.00 15.40 ? 103 ASP B CB  1 
ATOM   2603 C CG  . ASP B 1 101 ? -6.732  19.132  -10.739 1.00 19.13 ? 103 ASP B CG  1 
ATOM   2604 O OD1 . ASP B 1 101 ? -7.300  20.052  -10.126 1.00 17.64 ? 103 ASP B OD1 1 
ATOM   2605 O OD2 . ASP B 1 101 ? -6.496  19.194  -11.959 1.00 16.88 ? 103 ASP B OD2 1 
ATOM   2606 N N   . GLY B 1 102 ? -8.358  18.515  -8.013  1.00 17.38 ? 104 GLY B N   1 
ATOM   2607 C CA  . GLY B 1 102 ? -9.532  18.580  -7.160  1.00 13.99 ? 104 GLY B CA  1 
ATOM   2608 C C   . GLY B 1 102 ? -10.263 17.252  -7.031  1.00 15.03 ? 104 GLY B C   1 
ATOM   2609 O O   . GLY B 1 102 ? -9.765  16.185  -7.398  1.00 15.58 ? 104 GLY B O   1 
ATOM   2610 N N   . ASN B 1 103 ? -11.474 17.331  -6.463  1.00 13.94 ? 105 ASN B N   1 
ATOM   2611 C CA  . ASN B 1 103 ? -12.308 16.148  -6.244  1.00 13.42 ? 105 ASN B CA  1 
ATOM   2612 C C   . ASN B 1 103 ? -13.753 16.414  -6.652  1.00 12.31 ? 105 ASN B C   1 
ATOM   2613 O O   . ASN B 1 103 ? -14.232 17.550  -6.587  1.00 12.90 ? 105 ASN B O   1 
ATOM   2614 C CB  . ASN B 1 103 ? -12.251 15.675  -4.776  1.00 14.44 ? 105 ASN B CB  1 
ATOM   2615 C CG  . ASN B 1 103 ? -12.751 16.729  -3.804  1.00 14.74 ? 105 ASN B CG  1 
ATOM   2616 O OD1 . ASN B 1 103 ? -13.956 16.899  -3.616  1.00 15.81 ? 105 ASN B OD1 1 
ATOM   2617 N ND2 . ASN B 1 103 ? -11.816 17.429  -3.161  1.00 16.81 ? 105 ASN B ND2 1 
ATOM   2618 N N   . TYR B 1 104 ? -14.440 15.355  -7.097  1.00 13.27 ? 106 TYR B N   1 
ATOM   2619 C CA  . TYR B 1 104 ? -15.893 15.361  -7.275  1.00 12.28 ? 106 TYR B CA  1 
ATOM   2620 C C   . TYR B 1 104 ? -16.568 14.677  -6.092  1.00 13.47 ? 106 TYR B C   1 
ATOM   2621 O O   . TYR B 1 104 ? -16.096 13.648  -5.602  1.00 12.42 ? 106 TYR B O   1 
ATOM   2622 C CB  . TYR B 1 104 ? -16.358 14.604  -8.527  1.00 11.70 ? 106 TYR B CB  1 
ATOM   2623 C CG  . TYR B 1 104 ? -15.935 15.115  -9.876  1.00 12.67 ? 106 TYR B CG  1 
ATOM   2624 C CD1 . TYR B 1 104 ? -15.497 16.420  -10.063 1.00 12.86 ? 106 TYR B CD1 1 
ATOM   2625 C CD2 . TYR B 1 104 ? -15.971 14.265  -10.980 1.00 11.60 ? 106 TYR B CD2 1 
ATOM   2626 C CE1 . TYR B 1 104 ? -15.111 16.875  -11.320 1.00 12.93 ? 106 TYR B CE1 1 
ATOM   2627 C CE2 . TYR B 1 104 ? -15.589 14.706  -12.236 1.00 11.28 ? 106 TYR B CE2 1 
ATOM   2628 C CZ  . TYR B 1 104 ? -15.156 16.018  -12.396 1.00 12.15 ? 106 TYR B CZ  1 
ATOM   2629 O OH  . TYR B 1 104 ? -14.751 16.452  -13.648 1.00 11.98 ? 106 TYR B OH  1 
ATOM   2630 N N   . LYS B 1 105 ? -17.703 15.220  -5.682  1.00 11.60 ? 107 LYS B N   1 
ATOM   2631 C CA  . LYS B 1 105 ? -18.663 14.532  -4.826  1.00 11.68 ? 107 LYS B CA  1 
ATOM   2632 C C   . LYS B 1 105 ? -19.959 14.409  -5.602  1.00 12.36 ? 107 LYS B C   1 
ATOM   2633 O O   . LYS B 1 105 ? -20.446 15.402  -6.141  1.00 12.18 ? 107 LYS B O   1 
ATOM   2634 C CB  . LYS B 1 105 ? -18.909 15.317  -3.529  1.00 12.96 ? 107 LYS B CB  1 
ATOM   2635 C CG  . LYS B 1 105 ? -17.768 15.294  -2.544  1.00 18.27 ? 107 LYS B CG  1 
ATOM   2636 C CD  . LYS B 1 105 ? -18.357 15.544  -1.158  1.00 25.41 ? 107 LYS B CD  1 
ATOM   2637 C CE  . LYS B 1 105 ? -17.712 14.660  -0.135  1.00 26.82 ? 107 LYS B CE  1 
ATOM   2638 N NZ  . LYS B 1 105 ? -18.545 13.457  0.080   1.00 30.69 ? 107 LYS B NZ  1 
ATOM   2639 N N   . THR B 1 106 ? -20.508 13.198  -5.688  1.00 11.84 ? 108 THR B N   1 
ATOM   2640 C CA  . THR B 1 106 ? -21.716 13.012  -6.474  1.00 11.28 ? 108 THR B CA  1 
ATOM   2641 C C   . THR B 1 106 ? -22.778 12.342  -5.621  1.00 13.73 ? 108 THR B C   1 
ATOM   2642 O O   . THR B 1 106 ? -22.468 11.470  -4.804  1.00 13.09 ? 108 THR B O   1 
ATOM   2643 C CB  . THR B 1 106 ? -21.451 12.156  -7.726  1.00 10.14 ? 108 THR B CB  1 
ATOM   2644 O OG1 . THR B 1 106 ? -21.087 10.826  -7.336  1.00 13.53 ? 108 THR B OG1 1 
ATOM   2645 C CG2 . THR B 1 106 ? -20.278 12.749  -8.533  1.00 11.28 ? 108 THR B CG2 1 
ATOM   2646 N N   . ARG B 1 107 ? -24.030 12.769  -5.811  1.00 13.63 ? 109 ARG B N   1 
ATOM   2647 C CA  . ARG B 1 107 ? -25.198 12.086  -5.275  1.00 11.55 ? 109 ARG B CA  1 
ATOM   2648 C C   . ARG B 1 107 ? -26.184 11.860  -6.401  1.00 13.11 ? 109 ARG B C   1 
ATOM   2649 O O   . ARG B 1 107 ? -26.583 12.815  -7.075  1.00 13.42 ? 109 ARG B O   1 
ATOM   2650 C CB  . ARG B 1 107 ? -25.893 12.895  -4.166  1.00 13.36 ? 109 ARG B CB  1 
ATOM   2651 C CG  . ARG B 1 107 ? -26.905 12.059  -3.378  1.00 15.00 ? 109 ARG B CG  1 
ATOM   2652 C CD  . ARG B 1 107 ? -27.664 12.908  -2.363  1.00 19.41 ? 109 ARG B CD  1 
ATOM   2653 N NE  . ARG B 1 107 ? -28.619 12.114  -1.595  1.00 22.89 ? 109 ARG B NE  1 
ATOM   2654 C CZ  . ARG B 1 107 ? -29.849 11.815  -1.985  1.00 24.36 ? 109 ARG B CZ  1 
ATOM   2655 N NH1 . ARG B 1 107 ? -30.329 12.236  -3.144  1.00 22.91 ? 109 ARG B NH1 1 
ATOM   2656 N NH2 . ARG B 1 107 ? -30.611 11.061  -1.195  1.00 25.34 ? 109 ARG B NH2 1 
ATOM   2657 N N   . ALA B 1 108 ? -26.595 10.609  -6.586  1.00 13.14 ? 110 ALA B N   1 
ATOM   2658 C CA  . ALA B 1 108 ? -27.535 10.264  -7.637  1.00 11.66 ? 110 ALA B CA  1 
ATOM   2659 C C   . ALA B 1 108 ? -28.640 9.382   -7.078  1.00 12.97 ? 110 ALA B C   1 
ATOM   2660 O O   . ALA B 1 108 ? -28.432 8.594   -6.150  1.00 12.78 ? 110 ALA B O   1 
ATOM   2661 C CB  . ALA B 1 108 ? -26.842 9.532   -8.798  1.00 13.55 ? 110 ALA B CB  1 
ATOM   2662 N N   . GLU B 1 109 ? -29.812 9.494   -7.679  1.00 13.41 ? 111 GLU B N   1 
ATOM   2663 C CA  . GLU B 1 109 ? -30.873 8.524   -7.472  1.00 14.44 ? 111 GLU B CA  1 
ATOM   2664 C C   . GLU B 1 109 ? -31.118 7.816   -8.794  1.00 15.27 ? 111 GLU B C   1 
ATOM   2665 O O   . GLU B 1 109 ? -31.275 8.472   -9.833  1.00 13.75 ? 111 GLU B O   1 
ATOM   2666 C CB  . GLU B 1 109 ? -32.144 9.206   -6.964  1.00 13.85 ? 111 GLU B CB  1 
ATOM   2667 C CG  . GLU B 1 109 ? -31.939 9.759   -5.564  1.00 19.76 ? 111 GLU B CG  1 
ATOM   2668 C CD  . GLU B 1 109 ? -33.198 10.288  -4.935  1.00 28.00 ? 111 GLU B CD  1 
ATOM   2669 O OE1 . GLU B 1 109 ? -34.289 10.079  -5.510  1.00 28.25 ? 111 GLU B OE1 1 
ATOM   2670 O OE2 . GLU B 1 109 ? -33.087 10.923  -3.863  1.00 32.08 ? 111 GLU B OE2 1 
ATOM   2671 N N   . VAL B 1 110 ? -31.110 6.485   -8.754  1.00 12.83 ? 112 VAL B N   1 
ATOM   2672 C CA  . VAL B 1 110 ? -31.394 5.648   -9.913  1.00 13.92 ? 112 VAL B CA  1 
ATOM   2673 C C   . VAL B 1 110 ? -32.697 4.913   -9.616  1.00 13.25 ? 112 VAL B C   1 
ATOM   2674 O O   . VAL B 1 110 ? -32.771 4.157   -8.644  1.00 14.32 ? 112 VAL B O   1 
ATOM   2675 C CB  . VAL B 1 110 ? -30.251 4.656   -10.177 1.00 11.80 ? 112 VAL B CB  1 
ATOM   2676 C CG1 . VAL B 1 110 ? -30.509 3.869   -11.458 1.00 12.49 ? 112 VAL B CG1 1 
ATOM   2677 C CG2 . VAL B 1 110 ? -28.894 5.395   -10.224 1.00 13.27 ? 112 VAL B CG2 1 
ATOM   2678 N N   . LYS B 1 111 ? -33.720 5.123   -10.440 1.00 15.12 ? 113 LYS B N   1 
ATOM   2679 C CA  . LYS B 1 111 ? -35.029 4.542   -10.157 1.00 14.67 ? 113 LYS B CA  1 
ATOM   2680 C C   . LYS B 1 111 ? -35.842 4.547   -11.436 1.00 15.04 ? 113 LYS B C   1 
ATOM   2681 O O   . LYS B 1 111 ? -35.521 5.256   -12.388 1.00 16.10 ? 113 LYS B O   1 
ATOM   2682 C CB  . LYS B 1 111 ? -35.793 5.343   -9.101  1.00 15.57 ? 113 LYS B CB  1 
ATOM   2683 C CG  . LYS B 1 111 ? -36.173 6.746   -9.610  1.00 17.32 ? 113 LYS B CG  1 
ATOM   2684 C CD  . LYS B 1 111 ? -36.691 7.638   -8.484  1.00 22.23 ? 113 LYS B CD  1 
ATOM   2685 C CE  . LYS B 1 111 ? -35.737 8.779   -8.211  1.00 26.81 ? 113 LYS B CE  1 
ATOM   2686 N NZ  . LYS B 1 111 ? -36.109 9.591   -7.011  1.00 30.67 ? 113 LYS B NZ  1 
ATOM   2687 N N   . PHE B 1 112 ? -36.945 3.803   -11.418 1.00 15.21 ? 114 PHE B N   1 
ATOM   2688 C CA  . PHE B 1 112 ? -37.853 3.790   -12.551 1.00 15.76 ? 114 PHE B CA  1 
ATOM   2689 C C   . PHE B 1 112 ? -38.832 4.952   -12.436 1.00 17.37 ? 114 PHE B C   1 
ATOM   2690 O O   . PHE B 1 112 ? -39.300 5.277   -11.342 1.00 15.76 ? 114 PHE B O   1 
ATOM   2691 C CB  . PHE B 1 112 ? -38.606 2.458   -12.626 1.00 17.48 ? 114 PHE B CB  1 
ATOM   2692 C CG  . PHE B 1 112 ? -37.898 1.420   -13.450 1.00 16.30 ? 114 PHE B CG  1 
ATOM   2693 C CD1 . PHE B 1 112 ? -38.117 1.327   -14.823 1.00 16.58 ? 114 PHE B CD1 1 
ATOM   2694 C CD2 . PHE B 1 112 ? -36.970 0.583   -12.864 1.00 17.36 ? 114 PHE B CD2 1 
ATOM   2695 C CE1 . PHE B 1 112 ? -37.460 0.390   -15.579 1.00 18.45 ? 114 PHE B CE1 1 
ATOM   2696 C CE2 . PHE B 1 112 ? -36.297 -0.356  -13.617 1.00 17.00 ? 114 PHE B CE2 1 
ATOM   2697 C CZ  . PHE B 1 112 ? -36.534 -0.455  -14.977 1.00 15.97 ? 114 PHE B CZ  1 
ATOM   2698 N N   . GLU B 1 113 ? -39.111 5.584   -13.575 1.00 16.08 ? 115 GLU B N   1 
ATOM   2699 C CA  . GLU B 1 113 ? -40.155 6.592   -13.719 1.00 17.49 ? 115 GLU B CA  1 
ATOM   2700 C C   . GLU B 1 113 ? -40.987 6.116   -14.905 1.00 18.08 ? 115 GLU B C   1 
ATOM   2701 O O   . GLU B 1 113 ? -40.513 6.149   -16.045 1.00 18.45 ? 115 GLU B O   1 
ATOM   2702 C CB  . GLU B 1 113 ? -39.535 7.973   -13.965 1.00 16.68 ? 115 GLU B CB  1 
ATOM   2703 C CG  . GLU B 1 113 ? -38.690 8.395   -12.770 1.00 16.14 ? 115 GLU B CG  1 
ATOM   2704 C CD  . GLU B 1 113 ? -38.246 9.831   -12.780 1.00 20.32 ? 115 GLU B CD  1 
ATOM   2705 O OE1 . GLU B 1 113 ? -38.657 10.607  -13.674 1.00 21.50 ? 115 GLU B OE1 1 
ATOM   2706 O OE2 . GLU B 1 113 ? -37.434 10.164  -11.898 1.00 19.66 ? 115 GLU B OE2 1 
ATOM   2707 N N   . GLY B 1 114 ? -42.192 5.612   -14.640 1.00 19.66 ? 116 GLY B N   1 
ATOM   2708 C CA  . GLY B 1 114 ? -42.880 4.856   -15.677 1.00 18.10 ? 116 GLY B CA  1 
ATOM   2709 C C   . GLY B 1 114 ? -42.021 3.678   -16.098 1.00 20.38 ? 116 GLY B C   1 
ATOM   2710 O O   . GLY B 1 114 ? -41.505 2.932   -15.261 1.00 19.66 ? 116 GLY B O   1 
ATOM   2711 N N   . ASP B 1 115 ? -41.819 3.521   -17.404 1.00 17.58 ? 117 ASP B N   1 
ATOM   2712 C CA  . ASP B 1 115 ? -41.005 2.436   -17.932 1.00 18.61 ? 117 ASP B CA  1 
ATOM   2713 C C   . ASP B 1 115 ? -39.561 2.855   -18.203 1.00 18.99 ? 117 ASP B C   1 
ATOM   2714 O O   . ASP B 1 115 ? -38.815 2.102   -18.835 1.00 21.78 ? 117 ASP B O   1 
ATOM   2715 C CB  . ASP B 1 115 ? -41.642 1.904   -19.213 1.00 20.86 ? 117 ASP B CB  1 
ATOM   2716 C CG  . ASP B 1 115 ? -42.859 1.031   -18.939 1.00 30.37 ? 117 ASP B CG  1 
ATOM   2717 O OD1 . ASP B 1 115 ? -42.934 0.413   -17.850 1.00 26.51 ? 117 ASP B OD1 1 
ATOM   2718 O OD2 . ASP B 1 115 ? -43.760 0.997   -19.811 1.00 32.47 ? 117 ASP B OD2 1 
ATOM   2719 N N   . THR B 1 116 ? -39.157 4.035   -17.751 1.00 18.23 ? 118 THR B N   1 
ATOM   2720 C CA  . THR B 1 116 ? -37.836 4.585   -18.024 1.00 16.04 ? 118 THR B CA  1 
ATOM   2721 C C   . THR B 1 116 ? -36.953 4.472   -16.787 1.00 16.52 ? 118 THR B C   1 
ATOM   2722 O O   . THR B 1 116 ? -37.377 4.831   -15.687 1.00 16.08 ? 118 THR B O   1 
ATOM   2723 C CB  . THR B 1 116 ? -37.960 6.046   -18.464 1.00 15.87 ? 118 THR B CB  1 
ATOM   2724 O OG1 . THR B 1 116 ? -38.784 6.114   -19.633 1.00 18.69 ? 118 THR B OG1 1 
ATOM   2725 C CG2 . THR B 1 116 ? -36.603 6.648   -18.803 1.00 12.82 ? 118 THR B CG2 1 
ATOM   2726 N N   . LEU B 1 117 ? -35.729 3.972   -16.971 1.00 14.74 ? 119 LEU B N   1 
ATOM   2727 C CA  . LEU B 1 117 ? -34.735 3.976   -15.902 1.00 14.45 ? 119 LEU B CA  1 
ATOM   2728 C C   . LEU B 1 117 ? -34.044 5.338   -15.908 1.00 13.24 ? 119 LEU B C   1 
ATOM   2729 O O   . LEU B 1 117 ? -33.456 5.726   -16.921 1.00 13.34 ? 119 LEU B O   1 
ATOM   2730 C CB  . LEU B 1 117 ? -33.731 2.838   -16.104 1.00 16.01 ? 119 LEU B CB  1 
ATOM   2731 C CG  . LEU B 1 117 ? -32.746 2.454   -14.980 1.00 15.20 ? 119 LEU B CG  1 
ATOM   2732 C CD1 . LEU B 1 117 ? -31.537 3.385   -14.979 1.00 13.94 ? 119 LEU B CD1 1 
ATOM   2733 C CD2 . LEU B 1 117 ? -33.426 2.413   -13.595 1.00 13.51 ? 119 LEU B CD2 1 
ATOM   2734 N N   . VAL B 1 118 ? -34.139 6.068   -14.796 1.00 12.90 ? 120 VAL B N   1 
ATOM   2735 C CA  . VAL B 1 118 ? -33.640 7.436   -14.685 1.00 12.83 ? 120 VAL B CA  1 
ATOM   2736 C C   . VAL B 1 118 ? -32.487 7.479   -13.702 1.00 13.14 ? 120 VAL B C   1 
ATOM   2737 O O   . VAL B 1 118 ? -32.619 7.018   -12.563 1.00 13.21 ? 120 VAL B O   1 
ATOM   2738 C CB  . VAL B 1 118 ? -34.739 8.406   -14.223 1.00 12.73 ? 120 VAL B CB  1 
ATOM   2739 C CG1 . VAL B 1 118 ? -34.179 9.819   -14.181 1.00 13.49 ? 120 VAL B CG1 1 
ATOM   2740 C CG2 . VAL B 1 118 ? -35.915 8.342   -15.159 1.00 11.67 ? 120 VAL B CG2 1 
ATOM   2741 N N   . ASN B 1 119 ? -31.379 8.082   -14.125 1.00 13.50 ? 121 ASN B N   1 
ATOM   2742 C CA  . ASN B 1 119 ? -30.222 8.335   -13.272 1.00 12.37 ? 121 ASN B CA  1 
ATOM   2743 C C   . ASN B 1 119 ? -30.125 9.850   -13.140 1.00 13.51 ? 121 ASN B C   1 
ATOM   2744 O O   . ASN B 1 119 ? -29.741 10.528  -14.095 1.00 11.88 ? 121 ASN B O   1 
ATOM   2745 C CB  . ASN B 1 119 ? -28.940 7.748   -13.879 1.00 11.07 ? 121 ASN B CB  1 
ATOM   2746 C CG  . ASN B 1 119 ? -27.712 8.023   -13.015 1.00 13.35 ? 121 ASN B CG  1 
ATOM   2747 O OD1 . ASN B 1 119 ? -27.844 8.327   -11.829 1.00 13.06 ? 121 ASN B OD1 1 
ATOM   2748 N ND2 . ASN B 1 119 ? -26.512 7.916   -13.608 1.00 11.46 ? 121 ASN B ND2 1 
ATOM   2749 N N   . ARG B 1 120 ? -30.495 10.385  -11.973 1.00 13.00 ? 122 ARG B N   1 
ATOM   2750 C CA  . ARG B 1 120 ? -30.494 11.830  -11.727 1.00 14.10 ? 122 ARG B CA  1 
ATOM   2751 C C   . ARG B 1 120 ? -29.402 12.179  -10.728 1.00 13.54 ? 122 ARG B C   1 
ATOM   2752 O O   . ARG B 1 120 ? -29.397 11.646  -9.617  1.00 12.96 ? 122 ARG B O   1 
ATOM   2753 C CB  . ARG B 1 120 ? -31.849 12.306  -11.202 1.00 14.46 ? 122 ARG B CB  1 
ATOM   2754 C CG  . ARG B 1 120 ? -31.993 13.811  -11.254 1.00 21.16 ? 122 ARG B CG  1 
ATOM   2755 C CD  . ARG B 1 120 ? -33.374 14.217  -10.804 1.00 22.96 ? 122 ARG B CD  1 
ATOM   2756 N NE  . ARG B 1 120 ? -34.369 13.851  -11.797 1.00 19.42 ? 122 ARG B NE  1 
ATOM   2757 C CZ  . ARG B 1 120 ? -34.558 14.492  -12.944 1.00 19.75 ? 122 ARG B CZ  1 
ATOM   2758 N NH1 . ARG B 1 120 ? -33.877 15.587  -13.255 1.00 18.63 ? 122 ARG B NH1 1 
ATOM   2759 N NH2 . ARG B 1 120 ? -35.460 14.030  -13.797 1.00 17.93 ? 122 ARG B NH2 1 
ATOM   2760 N N   . ILE B 1 121 ? -28.504 13.093  -11.113 1.00 11.98 ? 123 ILE B N   1 
ATOM   2761 C CA  . ILE B 1 121 ? -27.229 13.291  -10.426 1.00 12.44 ? 123 ILE B CA  1 
ATOM   2762 C C   . ILE B 1 121 ? -27.051 14.745  -10.022 1.00 15.51 ? 123 ILE B C   1 
ATOM   2763 O O   . ILE B 1 121 ? -27.356 15.658  -10.800 1.00 14.31 ? 123 ILE B O   1 
ATOM   2764 C CB  . ILE B 1 121 ? -26.036 12.877  -11.312 1.00 11.29 ? 123 ILE B CB  1 
ATOM   2765 C CG1 . ILE B 1 121 ? -26.236 11.476  -11.872 1.00 12.02 ? 123 ILE B CG1 1 
ATOM   2766 C CG2 . ILE B 1 121 ? -24.733 12.998  -10.533 1.00 13.96 ? 123 ILE B CG2 1 
ATOM   2767 C CD1 . ILE B 1 121 ? -25.822 11.391  -13.316 1.00 14.50 ? 123 ILE B CD1 1 
ATOM   2768 N N   . GLU B 1 122 ? -26.483 14.947  -8.830  1.00 14.74 ? 124 GLU B N   1 
ATOM   2769 C CA  . GLU B 1 122 ? -25.888 16.214  -8.423  1.00 12.18 ? 124 GLU B CA  1 
ATOM   2770 C C   . GLU B 1 122 ? -24.390 16.003  -8.305  1.00 14.87 ? 124 GLU B C   1 
ATOM   2771 O O   . GLU B 1 122 ? -23.954 15.054  -7.649  1.00 13.95 ? 124 GLU B O   1 
ATOM   2772 C CB  . GLU B 1 122 ? -26.435 16.664  -7.068  1.00 17.43 ? 124 GLU B CB  1 
ATOM   2773 C CG  . GLU B 1 122 ? -27.847 17.180  -7.069  1.00 26.24 ? 124 GLU B CG  1 
ATOM   2774 C CD  . GLU B 1 122 ? -28.236 17.692  -5.689  1.00 35.74 ? 124 GLU B CD  1 
ATOM   2775 O OE1 . GLU B 1 122 ? -27.999 18.889  -5.414  1.00 37.38 ? 124 GLU B OE1 1 
ATOM   2776 O OE2 . GLU B 1 122 ? -28.726 16.877  -4.868  1.00 36.48 ? 124 GLU B OE2 1 
ATOM   2777 N N   . LEU B 1 123 ? -23.603 16.874  -8.937  1.00 10.79 ? 125 LEU B N   1 
ATOM   2778 C CA  . LEU B 1 123 ? -22.151 16.796  -8.880  1.00 11.49 ? 125 LEU B CA  1 
ATOM   2779 C C   . LEU B 1 123 ? -21.578 18.116  -8.391  1.00 12.62 ? 125 LEU B C   1 
ATOM   2780 O O   . LEU B 1 123 ? -21.883 19.181  -8.945  1.00 12.23 ? 125 LEU B O   1 
ATOM   2781 C CB  . LEU B 1 123 ? -21.549 16.449  -10.250 1.00 10.30 ? 125 LEU B CB  1 
ATOM   2782 C CG  . LEU B 1 123 ? -20.020 16.241  -10.314 1.00 9.23  ? 125 LEU B CG  1 
ATOM   2783 C CD1 . LEU B 1 123 ? -19.685 15.264  -11.426 1.00 9.50  ? 125 LEU B CD1 1 
ATOM   2784 C CD2 . LEU B 1 123 ? -19.295 17.574  -10.592 1.00 10.32 ? 125 LEU B CD2 1 
ATOM   2785 N N   . LYS B 1 124 ? -20.688 18.029  -7.414  1.00 12.37 ? 126 LYS B N   1 
ATOM   2786 C CA  . LYS B 1 124 ? -19.991 19.185  -6.893  1.00 12.07 ? 126 LYS B CA  1 
ATOM   2787 C C   . LYS B 1 124 ? -18.498 18.904  -6.949  1.00 14.35 ? 126 LYS B C   1 
ATOM   2788 O O   . LYS B 1 124 ? -18.022 17.903  -6.393  1.00 13.48 ? 126 LYS B O   1 
ATOM   2789 C CB  . LYS B 1 124 ? -20.457 19.489  -5.463  1.00 18.26 ? 126 LYS B CB  1 
ATOM   2790 C CG  . LYS B 1 124 ? -19.867 20.725  -4.839  1.00 22.39 ? 126 LYS B CG  1 
ATOM   2791 C CD  . LYS B 1 124 ? -19.709 20.511  -3.335  1.00 30.03 ? 126 LYS B CD  1 
ATOM   2792 C CE  . LYS B 1 124 ? -18.792 21.534  -2.712  1.00 30.44 ? 126 LYS B CE  1 
ATOM   2793 N NZ  . LYS B 1 124 ? -19.369 22.113  -1.474  1.00 38.19 ? 126 LYS B NZ  1 
ATOM   2794 N N   . GLY B 1 125 ? -17.769 19.766  -7.636  1.00 12.78 ? 127 GLY B N   1 
ATOM   2795 C CA  . GLY B 1 125 ? -16.322 19.653  -7.723  1.00 13.46 ? 127 GLY B CA  1 
ATOM   2796 C C   . GLY B 1 125 ? -15.690 20.861  -7.061  1.00 14.50 ? 127 GLY B C   1 
ATOM   2797 O O   . GLY B 1 125 ? -16.153 21.990  -7.247  1.00 12.79 ? 127 GLY B O   1 
ATOM   2798 N N   . ILE B 1 126 ? -14.630 20.621  -6.291  1.00 12.87 ? 128 ILE B N   1 
ATOM   2799 C CA  . ILE B 1 126 ? -13.908 21.694  -5.611  1.00 12.89 ? 128 ILE B CA  1 
ATOM   2800 C C   . ILE B 1 126 ? -12.420 21.393  -5.661  1.00 17.30 ? 128 ILE B C   1 
ATOM   2801 O O   . ILE B 1 126 ? -11.999 20.261  -5.922  1.00 15.35 ? 128 ILE B O   1 
ATOM   2802 C CB  . ILE B 1 126 ? -14.336 21.867  -4.137  1.00 18.11 ? 128 ILE B CB  1 
ATOM   2803 C CG1 . ILE B 1 126 ? -14.105 20.570  -3.367  1.00 19.12 ? 128 ILE B CG1 1 
ATOM   2804 C CG2 . ILE B 1 126 ? -15.765 22.336  -4.041  1.00 22.94 ? 128 ILE B CG2 1 
ATOM   2805 C CD1 . ILE B 1 126 ? -14.191 20.755  -1.862  1.00 23.99 ? 128 ILE B CD1 1 
ATOM   2806 N N   . ASP B 1 127 ? -11.626 22.422  -5.350  1.00 15.95 ? 129 ASP B N   1 
ATOM   2807 C CA  . ASP B 1 127 ? -10.176 22.324  -5.175  1.00 18.73 ? 129 ASP B CA  1 
ATOM   2808 C C   . ASP B 1 127 ? -9.436  22.025  -6.471  1.00 18.03 ? 129 ASP B C   1 
ATOM   2809 O O   . ASP B 1 127 ? -8.320  21.493  -6.424  1.00 16.26 ? 129 ASP B O   1 
ATOM   2810 C CB  . ASP B 1 127 ? -9.782  21.260  -4.137  1.00 19.45 ? 129 ASP B CB  1 
ATOM   2811 C CG  . ASP B 1 127 ? -8.737  21.759  -3.144  1.00 29.48 ? 129 ASP B CG  1 
ATOM   2812 O OD1 . ASP B 1 127 ? -8.196  22.860  -3.351  1.00 30.08 ? 129 ASP B OD1 1 
ATOM   2813 O OD2 . ASP B 1 127 ? -8.412  21.023  -2.185  1.00 34.65 ? 129 ASP B OD2 1 
ATOM   2814 N N   . PHE B 1 128 ? -10.019 22.359  -7.625  1.00 15.33 ? 130 PHE B N   1 
ATOM   2815 C CA  . PHE B 1 128 ? -9.388  22.077  -8.907  1.00 15.81 ? 130 PHE B CA  1 
ATOM   2816 C C   . PHE B 1 128 ? -8.447  23.218  -9.290  1.00 17.50 ? 130 PHE B C   1 
ATOM   2817 O O   . PHE B 1 128 ? -8.617  24.362  -8.857  1.00 18.46 ? 130 PHE B O   1 
ATOM   2818 C CB  . PHE B 1 128 ? -10.448 21.855  -9.999  1.00 16.91 ? 130 PHE B CB  1 
ATOM   2819 C CG  . PHE B 1 128 ? -11.070 20.478  -9.950  1.00 14.87 ? 130 PHE B CG  1 
ATOM   2820 C CD1 . PHE B 1 128 ? -10.467 19.401  -10.585 1.00 14.56 ? 130 PHE B CD1 1 
ATOM   2821 C CD2 . PHE B 1 128 ? -12.234 20.253  -9.222  1.00 14.41 ? 130 PHE B CD2 1 
ATOM   2822 C CE1 . PHE B 1 128 ? -11.017 18.119  -10.502 1.00 15.86 ? 130 PHE B CE1 1 
ATOM   2823 C CE2 . PHE B 1 128 ? -12.793 18.983  -9.144  1.00 11.79 ? 130 PHE B CE2 1 
ATOM   2824 C CZ  . PHE B 1 128 ? -12.184 17.918  -9.787  1.00 12.83 ? 130 PHE B CZ  1 
ATOM   2825 N N   . LYS B 1 129 ? -7.422  22.880  -10.073 1.00 17.14 ? 131 LYS B N   1 
ATOM   2826 C CA  . LYS B 1 129 ? -6.497  23.857  -10.644 1.00 17.12 ? 131 LYS B CA  1 
ATOM   2827 C C   . LYS B 1 129 ? -7.066  24.377  -11.959 1.00 20.57 ? 131 LYS B C   1 
ATOM   2828 O O   . LYS B 1 129 ? -7.461  23.582  -12.811 1.00 20.09 ? 131 LYS B O   1 
ATOM   2829 C CB  . LYS B 1 129 ? -5.130  23.203  -10.868 1.00 18.87 ? 131 LYS B CB  1 
ATOM   2830 C CG  . LYS B 1 129 ? -4.509  22.655  -9.589  1.00 16.89 ? 131 LYS B CG  1 
ATOM   2831 C CD  . LYS B 1 129 ? -3.285  21.793  -9.854  1.00 21.90 ? 131 LYS B CD  1 
ATOM   2832 C CE  . LYS B 1 129 ? -2.666  21.370  -8.529  1.00 24.67 ? 131 LYS B CE  1 
ATOM   2833 N N   . GLU B 1 130 ? -7.129  25.709  -12.131 1.00 22.66 ? 132 GLU B N   1 
ATOM   2834 C CA  . GLU B 1 130 ? -7.764  26.230  -13.346 1.00 23.60 ? 132 GLU B CA  1 
ATOM   2835 C C   . GLU B 1 130 ? -7.048  25.813  -14.625 1.00 23.96 ? 132 GLU B C   1 
ATOM   2836 O O   . GLU B 1 130 ? -7.702  25.617  -15.649 1.00 29.07 ? 132 GLU B O   1 
ATOM   2837 C CB  . GLU B 1 130 ? -7.909  27.747  -13.312 1.00 25.53 ? 132 GLU B CB  1 
ATOM   2838 C CG  . GLU B 1 130 ? -9.076  28.180  -12.470 1.00 31.29 ? 132 GLU B CG  1 
ATOM   2839 C CD  . GLU B 1 130 ? -10.406 27.952  -13.190 1.00 33.08 ? 132 GLU B CD  1 
ATOM   2840 O OE1 . GLU B 1 130 ? -10.407 27.668  -14.424 1.00 35.86 ? 132 GLU B OE1 1 
ATOM   2841 O OE2 . GLU B 1 130 ? -11.451 28.053  -12.516 1.00 28.26 ? 132 GLU B OE2 1 
ATOM   2842 N N   . ASP B 1 131 ? -5.731  25.661  -14.603 1.00 25.30 ? 133 ASP B N   1 
ATOM   2843 C CA  . ASP B 1 131 ? -5.028  25.105  -15.757 1.00 27.16 ? 133 ASP B CA  1 
ATOM   2844 C C   . ASP B 1 131 ? -4.440  23.729  -15.467 1.00 24.58 ? 133 ASP B C   1 
ATOM   2845 O O   . ASP B 1 131 ? -3.380  23.372  -15.982 1.00 24.17 ? 133 ASP B O   1 
ATOM   2846 C CB  . ASP B 1 131 ? -3.943  26.055  -16.263 1.00 32.51 ? 133 ASP B CB  1 
ATOM   2847 C CG  . ASP B 1 131 ? -3.667  25.883  -17.767 1.00 38.21 ? 133 ASP B CG  1 
ATOM   2848 O OD1 . ASP B 1 131 ? -4.576  25.454  -18.522 1.00 35.28 ? 133 ASP B OD1 1 
ATOM   2849 O OD2 . ASP B 1 131 ? -2.519  26.164  -18.191 1.00 43.52 ? 133 ASP B OD2 1 
ATOM   2850 N N   . GLY B 1 132 ? -5.133  22.940  -14.643 1.00 21.43 ? 134 GLY B N   1 
ATOM   2851 C CA  . GLY B 1 132 ? -4.799  21.545  -14.458 1.00 18.49 ? 134 GLY B CA  1 
ATOM   2852 C C   . GLY B 1 132 ? -5.373  20.679  -15.565 1.00 18.29 ? 134 GLY B C   1 
ATOM   2853 O O   . GLY B 1 132 ? -5.916  21.157  -16.562 1.00 15.44 ? 134 GLY B O   1 
ATOM   2854 N N   . ASN B 1 133 ? -5.251  19.360  -15.371 1.00 14.91 ? 135 ASN B N   1 
ATOM   2855 C CA  . ASN B 1 133 ? -5.648  18.433  -16.427 1.00 15.08 ? 135 ASN B CA  1 
ATOM   2856 C C   . ASN B 1 133 ? -7.149  18.426  -16.649 1.00 16.80 ? 135 ASN B C   1 
ATOM   2857 O O   . ASN B 1 133 ? -7.607  18.064  -17.739 1.00 17.10 ? 135 ASN B O   1 
ATOM   2858 C CB  . ASN B 1 133 ? -5.165  17.021  -16.086 1.00 16.66 ? 135 ASN B CB  1 
ATOM   2859 C CG  . ASN B 1 133 ? -3.663  16.886  -16.224 1.00 20.69 ? 135 ASN B CG  1 
ATOM   2860 O OD1 . ASN B 1 133 ? -3.033  17.597  -17.035 1.00 21.20 ? 135 ASN B OD1 1 
ATOM   2861 N ND2 . ASN B 1 133 ? -3.072  15.991  -15.437 1.00 16.22 ? 135 ASN B ND2 1 
ATOM   2862 N N   . ILE B 1 134 ? -7.928  18.838  -15.652 1.00 14.21 ? 136 ILE B N   1 
ATOM   2863 C CA  . ILE B 1 134 ? -9.374  18.690  -15.732 1.00 15.28 ? 136 ILE B CA  1 
ATOM   2864 C C   . ILE B 1 134 ? -9.965  19.980  -16.279 1.00 14.30 ? 136 ILE B C   1 
ATOM   2865 O O   . ILE B 1 134 ? -10.521 20.000  -17.382 1.00 14.83 ? 136 ILE B O   1 
ATOM   2866 C CB  . ILE B 1 134 ? -9.968  18.309  -14.362 1.00 15.94 ? 136 ILE B CB  1 
ATOM   2867 C CG1 . ILE B 1 134 ? -9.699  16.826  -14.067 1.00 17.65 ? 136 ILE B CG1 1 
ATOM   2868 C CG2 . ILE B 1 134 ? -11.470 18.483  -14.376 1.00 15.44 ? 136 ILE B CG2 1 
ATOM   2869 C CD1 . ILE B 1 134 ? -8.329  16.528  -13.576 1.00 18.78 ? 136 ILE B CD1 1 
ATOM   2870 N N   . LEU B 1 135 ? -9.826  21.075  -15.529 1.00 14.93 ? 137 LEU B N   1 
ATOM   2871 C CA  . LEU B 1 135 ? -10.377 22.348  -15.986 1.00 16.72 ? 137 LEU B CA  1 
ATOM   2872 C C   . LEU B 1 135 ? -9.659  22.860  -17.235 1.00 17.20 ? 137 LEU B C   1 
ATOM   2873 O O   . LEU B 1 135 ? -10.237 23.649  -18.001 1.00 17.11 ? 137 LEU B O   1 
ATOM   2874 C CB  . LEU B 1 135 ? -10.295 23.385  -14.857 1.00 16.42 ? 137 LEU B CB  1 
ATOM   2875 C CG  . LEU B 1 135 ? -11.327 23.177  -13.740 1.00 16.83 ? 137 LEU B CG  1 
ATOM   2876 C CD1 . LEU B 1 135 ? -11.229 24.270  -12.672 1.00 19.01 ? 137 LEU B CD1 1 
ATOM   2877 C CD2 . LEU B 1 135 ? -12.760 23.100  -14.309 1.00 17.24 ? 137 LEU B CD2 1 
ATOM   2878 N N   . GLY B 1 136 ? -8.415  22.427  -17.453 1.00 16.28 ? 138 GLY B N   1 
ATOM   2879 C CA  . GLY B 1 136 ? -7.672  22.774  -18.649 1.00 17.14 ? 138 GLY B CA  1 
ATOM   2880 C C   . GLY B 1 136 ? -7.909  21.867  -19.841 1.00 16.89 ? 138 GLY B C   1 
ATOM   2881 O O   . GLY B 1 136 ? -7.299  22.081  -20.892 1.00 16.52 ? 138 GLY B O   1 
ATOM   2882 N N   . HIS B 1 137 ? -8.785  20.869  -19.713 1.00 15.47 ? 139 HIS B N   1 
ATOM   2883 C CA  . HIS B 1 137 ? -9.130  19.954  -20.805 1.00 15.44 ? 139 HIS B CA  1 
ATOM   2884 C C   . HIS B 1 137 ? -7.884  19.347  -21.458 1.00 20.11 ? 139 HIS B C   1 
ATOM   2885 O O   . HIS B 1 137 ? -7.657  19.482  -22.664 1.00 18.00 ? 139 HIS B O   1 
ATOM   2886 C CB  . HIS B 1 137 ? -9.995  20.653  -21.867 1.00 19.16 ? 139 HIS B CB  1 
ATOM   2887 C CG  . HIS B 1 137 ? -11.378 21.000  -21.411 1.00 19.34 ? 139 HIS B CG  1 
ATOM   2888 N ND1 . HIS B 1 137 ? -11.692 22.211  -20.824 1.00 19.58 ? 139 HIS B ND1 1 
ATOM   2889 C CD2 . HIS B 1 137 ? -12.539 20.306  -21.489 1.00 19.21 ? 139 HIS B CD2 1 
ATOM   2890 C CE1 . HIS B 1 137 ? -12.986 22.240  -20.549 1.00 18.69 ? 139 HIS B CE1 1 
ATOM   2891 N NE2 . HIS B 1 137 ? -13.523 21.099  -20.941 1.00 21.85 ? 139 HIS B NE2 1 
ATOM   2892 N N   . LYS B 1 138 ? -7.084  18.653  -20.646 1.00 14.66 ? 140 LYS B N   1 
ATOM   2893 C CA  . LYS B 1 138 ? -5.829  18.077  -21.110 1.00 17.31 ? 140 LYS B CA  1 
ATOM   2894 C C   . LYS B 1 138 ? -5.869  16.550  -21.158 1.00 17.59 ? 140 LYS B C   1 
ATOM   2895 O O   . LYS B 1 138 ? -4.815  15.908  -21.138 1.00 16.13 ? 140 LYS B O   1 
ATOM   2896 C CB  . LYS B 1 138 ? -4.671  18.539  -20.222 1.00 20.43 ? 140 LYS B CB  1 
ATOM   2897 C CG  . LYS B 1 138 ? -4.475  20.046  -20.209 1.00 19.97 ? 140 LYS B CG  1 
ATOM   2898 C CD  . LYS B 1 138 ? -3.373  20.472  -19.263 1.00 20.74 ? 140 LYS B CD  1 
ATOM   2899 C CE  . LYS B 1 138 ? -3.282  21.986  -19.229 1.00 22.07 ? 140 LYS B CE  1 
ATOM   2900 N NZ  . LYS B 1 138 ? -2.188  22.466  -18.346 1.00 24.42 ? 140 LYS B NZ  1 
ATOM   2901 N N   . LEU B 1 139 ? -7.062  15.957  -21.199 1.00 14.74 ? 141 LEU B N   1 
ATOM   2902 C CA  . LEU B 1 139 ? -7.212  14.508  -21.172 1.00 15.77 ? 141 LEU B CA  1 
ATOM   2903 C C   . LEU B 1 139 ? -7.662  14.013  -22.541 1.00 17.50 ? 141 LEU B C   1 
ATOM   2904 O O   . LEU B 1 139 ? -8.497  14.650  -23.194 1.00 15.34 ? 141 LEU B O   1 
ATOM   2905 C CB  . LEU B 1 139 ? -8.241  14.089  -20.117 1.00 13.79 ? 141 LEU B CB  1 
ATOM   2906 C CG  . LEU B 1 139 ? -7.974  14.449  -18.656 1.00 13.29 ? 141 LEU B CG  1 
ATOM   2907 C CD1 . LEU B 1 139 ? -9.077  13.832  -17.787 1.00 12.52 ? 141 LEU B CD1 1 
ATOM   2908 C CD2 . LEU B 1 139 ? -6.599  13.978  -18.199 1.00 14.27 ? 141 LEU B CD2 1 
ATOM   2909 N N   . GLU B 1 140 ? -7.119  12.871  -22.965 1.00 14.38 ? 142 GLU B N   1 
ATOM   2910 C CA  . GLU B 1 140 ? -7.534  12.281  -24.225 1.00 15.82 ? 142 GLU B CA  1 
ATOM   2911 C C   . GLU B 1 140 ? -9.004  11.903  -24.187 1.00 16.05 ? 142 GLU B C   1 
ATOM   2912 O O   . GLU B 1 140 ? -9.562  11.579  -23.137 1.00 14.88 ? 142 GLU B O   1 
ATOM   2913 C CB  . GLU B 1 140 ? -6.700  11.041  -24.534 1.00 16.97 ? 142 GLU B CB  1 
ATOM   2914 C CG  . GLU B 1 140 ? -5.312  11.393  -24.923 1.00 20.53 ? 142 GLU B CG  1 
ATOM   2915 C CD  . GLU B 1 140 ? -4.445  10.190  -25.166 1.00 19.87 ? 142 GLU B CD  1 
ATOM   2916 O OE1 . GLU B 1 140 ? -4.944  9.044   -25.088 1.00 18.10 ? 142 GLU B OE1 1 
ATOM   2917 O OE2 . GLU B 1 140 ? -3.258  10.411  -25.450 1.00 18.58 ? 142 GLU B OE2 1 
ATOM   2918 N N   . TYR B 1 141 ? -9.629  11.917  -25.357 1.00 13.35 ? 143 TYR B N   1 
ATOM   2919 C CA  . TYR B 1 141 ? -11.021 11.502  -25.469 1.00 15.94 ? 143 TYR B CA  1 
ATOM   2920 C C   . TYR B 1 141 ? -11.059 10.009  -25.762 1.00 14.96 ? 143 TYR B C   1 
ATOM   2921 O O   . TYR B 1 141 ? -11.304 9.570   -26.889 1.00 15.84 ? 143 TYR B O   1 
ATOM   2922 C CB  . TYR B 1 141 ? -11.737 12.293  -26.549 1.00 15.81 ? 143 TYR B CB  1 
ATOM   2923 C CG  . TYR B 1 141 ? -13.220 12.028  -26.610 1.00 15.85 ? 143 TYR B CG  1 
ATOM   2924 C CD1 . TYR B 1 141 ? -14.086 12.525  -25.630 1.00 15.08 ? 143 TYR B CD1 1 
ATOM   2925 C CD2 . TYR B 1 141 ? -13.765 11.293  -27.665 1.00 15.57 ? 143 TYR B CD2 1 
ATOM   2926 C CE1 . TYR B 1 141 ? -15.447 12.276  -25.703 1.00 15.31 ? 143 TYR B CE1 1 
ATOM   2927 C CE2 . TYR B 1 141 ? -15.121 11.054  -27.755 1.00 12.28 ? 143 TYR B CE2 1 
ATOM   2928 C CZ  . TYR B 1 141 ? -15.957 11.552  -26.779 1.00 13.76 ? 143 TYR B CZ  1 
ATOM   2929 O OH  . TYR B 1 141 ? -17.303 11.302  -26.876 1.00 15.37 ? 143 TYR B OH  1 
ATOM   2930 N N   . ASN B 1 142 ? -10.842 9.229   -24.710 1.00 14.04 ? 144 ASN B N   1 
ATOM   2931 C CA  . ASN B 1 142 ? -10.935 7.778   -24.751 1.00 16.84 ? 144 ASN B CA  1 
ATOM   2932 C C   . ASN B 1 142 ? -11.101 7.288   -23.311 1.00 16.83 ? 144 ASN B C   1 
ATOM   2933 O O   . ASN B 1 142 ? -11.298 8.086   -22.387 1.00 13.90 ? 144 ASN B O   1 
ATOM   2934 C CB  . ASN B 1 142 ? -9.717  7.190   -25.483 1.00 18.10 ? 144 ASN B CB  1 
ATOM   2935 C CG  . ASN B 1 142 ? -8.400  7.652   -24.909 1.00 19.36 ? 144 ASN B CG  1 
ATOM   2936 O OD1 . ASN B 1 142 ? -8.270  7.865   -23.698 1.00 16.94 ? 144 ASN B OD1 1 
ATOM   2937 N ND2 . ASN B 1 142 ? -7.429  7.913   -25.801 1.00 16.23 ? 144 ASN B ND2 1 
ATOM   2938 N N   . TYR B 1 143 ? -11.031 5.974   -23.107 1.00 14.89 ? 145 TYR B N   1 
ATOM   2939 C CA  . TYR B 1 143 ? -11.345 5.457   -21.781 1.00 15.24 ? 145 TYR B CA  1 
ATOM   2940 C C   . TYR B 1 143 ? -10.545 4.200   -21.484 1.00 19.73 ? 145 TYR B C   1 
ATOM   2941 O O   . TYR B 1 143 ? -10.447 3.307   -22.331 1.00 18.50 ? 145 TYR B O   1 
ATOM   2942 C CB  . TYR B 1 143 ? -12.837 5.152   -21.636 1.00 15.79 ? 145 TYR B CB  1 
ATOM   2943 C CG  . TYR B 1 143 ? -13.282 5.334   -20.210 1.00 15.47 ? 145 TYR B CG  1 
ATOM   2944 C CD1 . TYR B 1 143 ? -13.420 6.611   -19.674 1.00 14.88 ? 145 TYR B CD1 1 
ATOM   2945 C CD2 . TYR B 1 143 ? -13.504 4.238   -19.378 1.00 15.19 ? 145 TYR B CD2 1 
ATOM   2946 C CE1 . TYR B 1 143 ? -13.813 6.801   -18.353 1.00 11.49 ? 145 TYR B CE1 1 
ATOM   2947 C CE2 . TYR B 1 143 ? -13.893 4.421   -18.058 1.00 14.56 ? 145 TYR B CE2 1 
ATOM   2948 C CZ  . TYR B 1 143 ? -14.034 5.701   -17.556 1.00 13.19 ? 145 TYR B CZ  1 
ATOM   2949 O OH  . TYR B 1 143 ? -14.416 5.888   -16.247 1.00 13.32 ? 145 TYR B OH  1 
ATOM   2950 N N   . ASN B 1 144 ? -9.984  4.134   -20.272 1.00 18.02 ? 146 ASN B N   1 
ATOM   2951 C CA  . ASN B 1 144 ? -9.397  2.909   -19.729 1.00 16.78 ? 146 ASN B CA  1 
ATOM   2952 C C   . ASN B 1 144 ? -10.347 2.427   -18.639 1.00 15.95 ? 146 ASN B C   1 
ATOM   2953 O O   . ASN B 1 144 ? -10.432 3.053   -17.581 1.00 15.83 ? 146 ASN B O   1 
ATOM   2954 C CB  . ASN B 1 144 ? -8.009  3.128   -19.121 1.00 20.37 ? 146 ASN B CB  1 
ATOM   2955 C CG  . ASN B 1 144 ? -7.023  3.735   -20.082 1.00 23.76 ? 146 ASN B CG  1 
ATOM   2956 O OD1 . ASN B 1 144 ? -6.829  3.228   -21.187 1.00 23.69 ? 146 ASN B OD1 1 
ATOM   2957 N ND2 . ASN B 1 144 ? -6.310  4.782   -19.620 1.00 22.94 ? 146 ASN B ND2 1 
ATOM   2958 N N   . ASP B 1 145 ? -11.071 1.342   -18.893 1.00 11.24 ? 147 ASP B N   1 
ATOM   2959 C CA  . ASP B 1 145 ? -12.001 0.856   -17.878 1.00 14.55 ? 147 ASP B CA  1 
ATOM   2960 C C   . ASP B 1 145 ? -11.256 0.152   -16.753 1.00 14.29 ? 147 ASP B C   1 
ATOM   2961 O O   . ASP B 1 145 ? -10.098 -0.242  -16.887 1.00 13.61 ? 147 ASP B O   1 
ATOM   2962 C CB  . ASP B 1 145 ? -13.026 -0.089  -18.493 1.00 15.19 ? 147 ASP B CB  1 
ATOM   2963 C CG  . ASP B 1 145 ? -13.975 0.622   -19.422 1.00 15.33 ? 147 ASP B CG  1 
ATOM   2964 O OD1 . ASP B 1 145 ? -14.939 1.248   -18.917 1.00 12.64 ? 147 ASP B OD1 1 
ATOM   2965 O OD2 . ASP B 1 145 ? -13.727 0.569   -20.645 1.00 14.36 ? 147 ASP B OD2 1 
ATOM   2966 N N   . HIS B 1 146 ? -11.930 0.013   -15.614 1.00 14.89 ? 148 HIS B N   1 
ATOM   2967 C CA  . HIS B 1 146 ? -11.385 -0.792  -14.537 1.00 16.48 ? 148 HIS B CA  1 
ATOM   2968 C C   . HIS B 1 146 ? -12.518 -1.563  -13.876 1.00 13.72 ? 148 HIS B C   1 
ATOM   2969 O O   . HIS B 1 146 ? -13.659 -1.101  -13.818 1.00 14.79 ? 148 HIS B O   1 
ATOM   2970 C CB  . HIS B 1 146 ? -10.637 0.064   -13.512 1.00 17.92 ? 148 HIS B CB  1 
ATOM   2971 C CG  . HIS B 1 146 ? -9.715  -0.724  -12.639 1.00 20.61 ? 148 HIS B CG  1 
ATOM   2972 N ND1 . HIS B 1 146 ? -10.122 -1.307  -11.456 1.00 20.56 ? 148 HIS B ND1 1 
ATOM   2973 C CD2 . HIS B 1 146 ? -8.411  -1.055  -12.794 1.00 26.57 ? 148 HIS B CD2 1 
ATOM   2974 C CE1 . HIS B 1 146 ? -9.101  -1.947  -10.912 1.00 22.84 ? 148 HIS B CE1 1 
ATOM   2975 N NE2 . HIS B 1 146 ? -8.053  -1.812  -11.704 1.00 25.13 ? 148 HIS B NE2 1 
ATOM   2976 N N   . GLN B 1 147 ? -12.199 -2.755  -13.390 1.00 15.99 ? 149 GLN B N   1 
ATOM   2977 C CA  . GLN B 1 147 ? -13.203 -3.576  -12.727 1.00 15.98 ? 149 GLN B CA  1 
ATOM   2978 C C   . GLN B 1 147 ? -13.575 -2.953  -11.384 1.00 14.23 ? 149 GLN B C   1 
ATOM   2979 O O   . GLN B 1 147 ? -12.793 -2.220  -10.786 1.00 15.14 ? 149 GLN B O   1 
ATOM   2980 C CB  . GLN B 1 147 ? -12.643 -4.978  -12.540 1.00 16.70 ? 149 GLN B CB  1 
ATOM   2981 C CG  . GLN B 1 147 ? -11.398 -4.995  -11.694 1.00 20.35 ? 149 GLN B CG  1 
ATOM   2982 C CD  . GLN B 1 147 ? -10.122 -4.968  -12.523 1.00 31.74 ? 149 GLN B CD  1 
ATOM   2983 O OE1 . GLN B 1 147 ? -10.122 -4.547  -13.700 1.00 28.45 ? 149 GLN B OE1 1 
ATOM   2984 N NE2 . GLN B 1 147 ? -9.027  -5.431  -11.925 1.00 34.18 ? 149 GLN B NE2 1 
ATOM   2985 N N   . VAL B 1 148 ? -14.782 -3.243  -10.909 1.00 15.60 ? 150 VAL B N   1 
ATOM   2986 C CA  . VAL B 1 148 ? -15.267 -2.715  -9.637  1.00 13.23 ? 150 VAL B CA  1 
ATOM   2987 C C   . VAL B 1 148 ? -15.622 -3.888  -8.737  1.00 17.51 ? 150 VAL B C   1 
ATOM   2988 O O   . VAL B 1 148 ? -16.444 -4.737  -9.108  1.00 14.43 ? 150 VAL B O   1 
ATOM   2989 C CB  . VAL B 1 148 ? -16.490 -1.795  -9.818  1.00 14.50 ? 150 VAL B CB  1 
ATOM   2990 C CG1 . VAL B 1 148 ? -17.009 -1.318  -8.440  1.00 16.12 ? 150 VAL B CG1 1 
ATOM   2991 C CG2 . VAL B 1 148 ? -16.133 -0.596  -10.683 1.00 14.15 ? 150 VAL B CG2 1 
ATOM   2992 N N   . TYR B 1 149 ? -15.020 -3.923  -7.551  1.00 17.76 ? 151 TYR B N   1 
ATOM   2993 C CA  . TYR B 1 149 ? -15.290 -4.978  -6.575  1.00 17.99 ? 151 TYR B CA  1 
ATOM   2994 C C   . TYR B 1 149 ? -16.421 -4.518  -5.670  1.00 16.78 ? 151 TYR B C   1 
ATOM   2995 O O   . TYR B 1 149 ? -16.248 -3.602  -4.859  1.00 18.13 ? 151 TYR B O   1 
ATOM   2996 C CB  . TYR B 1 149 ? -14.032 -5.310  -5.783  1.00 19.98 ? 151 TYR B CB  1 
ATOM   2997 C CG  . TYR B 1 149 ? -14.187 -6.484  -4.843  1.00 24.82 ? 151 TYR B CG  1 
ATOM   2998 C CD1 . TYR B 1 149 ? -14.247 -7.779  -5.337  1.00 29.94 ? 151 TYR B CD1 1 
ATOM   2999 C CD2 . TYR B 1 149 ? -14.182 -6.305  -3.465  1.00 24.89 ? 151 TYR B CD2 1 
ATOM   3000 C CE1 . TYR B 1 149 ? -14.371 -8.863  -4.488  1.00 27.79 ? 151 TYR B CE1 1 
ATOM   3001 C CE2 . TYR B 1 149 ? -14.289 -7.390  -2.604  1.00 27.47 ? 151 TYR B CE2 1 
ATOM   3002 C CZ  . TYR B 1 149 ? -14.381 -8.664  -3.132  1.00 31.67 ? 151 TYR B CZ  1 
ATOM   3003 O OH  . TYR B 1 149 ? -14.486 -9.757  -2.298  1.00 41.30 ? 151 TYR B OH  1 
ATOM   3004 N N   . ILE B 1 150 ? -17.583 -5.145  -5.820  1.00 17.13 ? 152 ILE B N   1 
ATOM   3005 C CA  . ILE B 1 150 ? -18.789 -4.733  -5.120  1.00 15.43 ? 152 ILE B CA  1 
ATOM   3006 C C   . ILE B 1 150 ? -18.851 -5.487  -3.798  1.00 20.00 ? 152 ILE B C   1 
ATOM   3007 O O   . ILE B 1 150 ? -18.877 -6.717  -3.784  1.00 18.22 ? 152 ILE B O   1 
ATOM   3008 C CB  . ILE B 1 150 ? -20.037 -5.004  -5.973  1.00 20.39 ? 152 ILE B CB  1 
ATOM   3009 C CG1 . ILE B 1 150 ? -19.876 -4.259  -7.306  1.00 17.51 ? 152 ILE B CG1 1 
ATOM   3010 C CG2 . ILE B 1 150 ? -21.318 -4.679  -5.206  1.00 20.14 ? 152 ILE B CG2 1 
ATOM   3011 C CD1 . ILE B 1 150 ? -20.348 -2.851  -7.242  1.00 17.91 ? 152 ILE B CD1 1 
ATOM   3012 N N   . MET B 1 151 ? -18.869 -4.764  -2.691  1.00 19.46 ? 153 MET B N   1 
ATOM   3013 C CA  . MET B 1 151 ? -18.944 -5.394  -1.383  1.00 20.30 ? 153 MET B CA  1 
ATOM   3014 C C   . MET B 1 151 ? -20.276 -5.086  -0.718  1.00 20.54 ? 153 MET B C   1 
ATOM   3015 O O   . MET B 1 151 ? -20.718 -3.934  -0.695  1.00 18.48 ? 153 MET B O   1 
ATOM   3016 C CB  . MET B 1 151 ? -17.780 -4.964  -0.495  1.00 22.52 ? 153 MET B CB  1 
ATOM   3017 C CG  . MET B 1 151 ? -16.459 -4.995  -1.215  1.00 28.41 ? 153 MET B CG  1 
ATOM   3018 S SD  . MET B 1 151 ? -15.089 -4.525  -0.160  1.00 36.15 ? 153 MET B SD  1 
ATOM   3019 C CE  . MET B 1 151 ? -14.993 -2.767  -0.517  1.00 30.71 ? 153 MET B CE  1 
ATOM   3020 N N   . ALA B 1 152 ? -20.914 -6.128  -0.190  1.00 23.57 ? 154 ALA B N   1 
ATOM   3021 C CA  . ALA B 1 152 ? -22.147 -5.944  0.557   1.00 22.47 ? 154 ALA B CA  1 
ATOM   3022 C C   . ALA B 1 152 ? -21.893 -5.101  1.799   1.00 26.79 ? 154 ALA B C   1 
ATOM   3023 O O   . ALA B 1 152 ? -20.867 -5.242  2.471   1.00 28.64 ? 154 ALA B O   1 
ATOM   3024 C CB  . ALA B 1 152 ? -22.730 -7.301  0.955   1.00 29.53 ? 154 ALA B CB  1 
ATOM   3025 N N   . ASP B 1 153 ? -22.831 -4.211  2.098   1.00 24.64 ? 155 ASP B N   1 
ATOM   3026 C CA  . ASP B 1 153 ? -22.814 -3.407  3.316   1.00 31.26 ? 155 ASP B CA  1 
ATOM   3027 C C   . ASP B 1 153 ? -24.110 -3.747  4.048   1.00 30.88 ? 155 ASP B C   1 
ATOM   3028 O O   . ASP B 1 153 ? -25.146 -3.117  3.837   1.00 28.75 ? 155 ASP B O   1 
ATOM   3029 C CB  . ASP B 1 153 ? -22.715 -1.907  2.982   1.00 29.81 ? 155 ASP B CB  1 
ATOM   3030 C CG  . ASP B 1 153 ? -22.512 -1.041  4.211   1.00 38.02 ? 155 ASP B CG  1 
ATOM   3031 O OD1 . ASP B 1 153 ? -22.688 -1.548  5.338   1.00 41.20 ? 155 ASP B OD1 1 
ATOM   3032 O OD2 . ASP B 1 153 ? -22.177 0.154   4.046   1.00 40.70 ? 155 ASP B OD2 1 
ATOM   3033 N N   . LYS B 1 154 ? -24.068 -4.762  4.900   1.00 32.39 ? 156 LYS B N   1 
ATOM   3034 C CA  . LYS B 1 154 ? -25.310 -5.220  5.510   1.00 37.63 ? 156 LYS B CA  1 
ATOM   3035 C C   . LYS B 1 154 ? -25.891 -4.195  6.461   1.00 35.33 ? 156 LYS B C   1 
ATOM   3036 O O   . LYS B 1 154 ? -27.097 -4.218  6.734   1.00 36.33 ? 156 LYS B O   1 
ATOM   3037 C CB  . LYS B 1 154 ? -25.055 -6.487  6.260   1.00 39.83 ? 156 LYS B CB  1 
ATOM   3038 C CG  . LYS B 1 154 ? -24.492 -7.453  5.348   1.00 41.35 ? 156 LYS B CG  1 
ATOM   3039 C CD  . LYS B 1 154 ? -23.980 -8.502  6.235   1.00 47.47 ? 156 LYS B CD  1 
ATOM   3040 C CE  . LYS B 1 154 ? -22.462 -8.541  6.096   1.00 50.47 ? 156 LYS B CE  1 
ATOM   3041 N NZ  . LYS B 1 154 ? -21.732 -8.805  7.396   1.00 50.20 ? 156 LYS B NZ  1 
ATOM   3042 N N   . GLN B 1 155 ? -25.047 -3.320  7.002   1.00 35.54 ? 157 GLN B N   1 
ATOM   3043 C CA  . GLN B 1 155 ? -25.534 -2.294  7.908   1.00 38.53 ? 157 GLN B CA  1 
ATOM   3044 C C   . GLN B 1 155 ? -26.514 -1.385  7.192   1.00 40.33 ? 157 GLN B C   1 
ATOM   3045 O O   . GLN B 1 155 ? -27.585 -1.074  7.718   1.00 36.54 ? 157 GLN B O   1 
ATOM   3046 C CB  . GLN B 1 155 ? -24.370 -1.469  8.462   1.00 43.38 ? 157 GLN B CB  1 
ATOM   3047 C CG  . GLN B 1 155 ? -23.276 -2.255  9.164   1.00 50.82 ? 157 GLN B CG  1 
ATOM   3048 C CD  . GLN B 1 155 ? -22.286 -2.856  8.182   1.00 51.89 ? 157 GLN B CD  1 
ATOM   3049 O OE1 . GLN B 1 155 ? -22.571 -3.860  7.531   1.00 51.42 ? 157 GLN B OE1 1 
ATOM   3050 N NE2 . GLN B 1 155 ? -21.117 -2.222  8.056   1.00 59.32 ? 157 GLN B NE2 1 
ATOM   3051 N N   . LYS B 1 156 ? -26.154 -0.935  5.991   1.00 35.31 ? 158 LYS B N   1 
ATOM   3052 C CA  . LYS B 1 156 ? -26.952 0.032   5.260   1.00 32.52 ? 158 LYS B CA  1 
ATOM   3053 C C   . LYS B 1 156 ? -27.889 -0.629  4.267   1.00 33.16 ? 158 LYS B C   1 
ATOM   3054 O O   . LYS B 1 156 ? -28.601 0.078   3.549   1.00 33.46 ? 158 LYS B O   1 
ATOM   3055 C CB  . LYS B 1 156 ? -26.035 1.027   4.546   1.00 36.55 ? 158 LYS B CB  1 
ATOM   3056 C CG  . LYS B 1 156 ? -25.073 1.754   5.489   1.00 37.33 ? 158 LYS B CG  1 
ATOM   3057 C CD  . LYS B 1 156 ? -24.666 3.130   4.958   1.00 42.31 ? 158 LYS B CD  1 
ATOM   3058 C CE  . LYS B 1 156 ? -25.863 4.077   4.881   1.00 43.95 ? 158 LYS B CE  1 
ATOM   3059 N NZ  . LYS B 1 156 ? -25.580 5.320   4.093   1.00 42.74 ? 158 LYS B NZ  1 
ATOM   3060 N N   . ASN B 1 157 ? -27.900 -1.965  4.212   1.00 26.45 ? 159 ASN B N   1 
ATOM   3061 C CA  . ASN B 1 157 ? -28.744 -2.720  3.295   1.00 29.68 ? 159 ASN B CA  1 
ATOM   3062 C C   . ASN B 1 157 ? -28.372 -2.412  1.840   1.00 29.49 ? 159 ASN B C   1 
ATOM   3063 O O   . ASN B 1 157 ? -29.206 -2.490  0.937   1.00 27.52 ? 159 ASN B O   1 
ATOM   3064 C CB  . ASN B 1 157 ? -30.222 -2.433  3.588   1.00 31.36 ? 159 ASN B CB  1 
ATOM   3065 C CG  . ASN B 1 157 ? -31.105 -3.652  3.435   1.00 37.80 ? 159 ASN B CG  1 
ATOM   3066 O OD1 . ASN B 1 157 ? -30.687 -4.782  3.696   1.00 39.30 ? 159 ASN B OD1 1 
ATOM   3067 N ND2 . ASN B 1 157 ? -32.375 -3.413  3.131   1.00 39.74 ? 159 ASN B ND2 1 
ATOM   3068 N N   . GLY B 1 158 ? -27.102 -2.076  1.603   1.00 22.90 ? 160 GLY B N   1 
ATOM   3069 C CA  . GLY B 1 158 ? -26.644 -1.703  0.277   1.00 20.41 ? 160 GLY B CA  1 
ATOM   3070 C C   . GLY B 1 158 ? -25.258 -2.226  -0.035  1.00 21.23 ? 160 GLY B C   1 
ATOM   3071 O O   . GLY B 1 158 ? -24.859 -3.289  0.464   1.00 20.59 ? 160 GLY B O   1 
ATOM   3072 N N   . ILE B 1 159 ? -24.501 -1.499  -0.861  1.00 20.07 ? 161 ILE B N   1 
ATOM   3073 C CA  . ILE B 1 159 ? -23.181 -1.952  -1.281  1.00 16.78 ? 161 ILE B CA  1 
ATOM   3074 C C   . ILE B 1 159 ? -22.204 -0.791  -1.240  1.00 16.31 ? 161 ILE B C   1 
ATOM   3075 O O   . ILE B 1 159 ? -22.590 0.376   -1.177  1.00 14.83 ? 161 ILE B O   1 
ATOM   3076 C CB  . ILE B 1 159 ? -23.192 -2.623  -2.685  1.00 18.66 ? 161 ILE B CB  1 
ATOM   3077 C CG1 . ILE B 1 159 ? -23.718 -1.702  -3.805  1.00 17.11 ? 161 ILE B CG1 1 
ATOM   3078 C CG2 . ILE B 1 159 ? -23.998 -3.906  -2.643  1.00 15.00 ? 161 ILE B CG2 1 
ATOM   3079 C CD1 . ILE B 1 159 ? -22.707 -0.732  -4.409  1.00 18.05 ? 161 ILE B CD1 1 
ATOM   3080 N N   . LYS B 1 160 ? -20.919 -1.137  -1.250  1.00 16.07 ? 162 LYS B N   1 
ATOM   3081 C CA  . LYS B 1 160 ? -19.849 -0.153  -1.288  1.00 17.67 ? 162 LYS B CA  1 
ATOM   3082 C C   . LYS B 1 160 ? -18.755 -0.667  -2.207  1.00 15.24 ? 162 LYS B C   1 
ATOM   3083 O O   . LYS B 1 160 ? -18.682 -1.857  -2.520  1.00 16.02 ? 162 LYS B O   1 
ATOM   3084 C CB  . LYS B 1 160 ? -19.270 0.137   0.100   1.00 20.00 ? 162 LYS B CB  1 
ATOM   3085 C CG  . LYS B 1 160 ? -18.965 -1.096  0.889   1.00 25.90 ? 162 LYS B CG  1 
ATOM   3086 C CD  . LYS B 1 160 ? -18.632 -0.775  2.358   1.00 32.34 ? 162 LYS B CD  1 
ATOM   3087 C CE  . LYS B 1 160 ? -17.534 -1.700  2.880   1.00 37.93 ? 162 LYS B CE  1 
ATOM   3088 N NZ  . LYS B 1 160 ? -17.713 -1.998  4.329   1.00 44.77 ? 162 LYS B NZ  1 
ATOM   3089 N N   . ALA B 1 161 ? -17.915 0.255   -2.664  1.00 17.58 ? 163 ALA B N   1 
ATOM   3090 C CA  . ALA B 1 161 ? -16.804 -0.115  -3.531  1.00 16.47 ? 163 ALA B CA  1 
ATOM   3091 C C   . ALA B 1 161 ? -15.789 1.018   -3.531  1.00 17.04 ? 163 ALA B C   1 
ATOM   3092 O O   . ALA B 1 161 ? -16.145 2.185   -3.364  1.00 16.39 ? 163 ALA B O   1 
ATOM   3093 C CB  . ALA B 1 161 ? -17.282 -0.401  -4.964  1.00 17.53 ? 163 ALA B CB  1 
ATOM   3094 N N   . ASN B 1 162 ? -14.528 0.669   -3.735  1.00 14.87 ? 164 ASN B N   1 
ATOM   3095 C CA  . ASN B 1 162 ? -13.495 1.666   -3.990  1.00 16.55 ? 164 ASN B CA  1 
ATOM   3096 C C   . ASN B 1 162 ? -12.660 1.167   -5.156  1.00 17.61 ? 164 ASN B C   1 
ATOM   3097 O O   . ASN B 1 162 ? -12.249 0.004   -5.161  1.00 17.88 ? 164 ASN B O   1 
ATOM   3098 C CB  . ASN B 1 162 ? -12.636 1.911   -2.736  1.00 21.83 ? 164 ASN B CB  1 
ATOM   3099 C CG  . ASN B 1 162 ? -11.222 2.392   -3.059  1.00 29.62 ? 164 ASN B CG  1 
ATOM   3100 O OD1 . ASN B 1 162 ? -11.014 3.547   -3.469  1.00 29.67 ? 164 ASN B OD1 1 
ATOM   3101 N ND2 . ASN B 1 162 ? -10.233 1.528   -2.818  1.00 31.10 ? 164 ASN B ND2 1 
ATOM   3102 N N   . PHE B 1 163 ? -12.438 2.022   -6.158  1.00 14.91 ? 165 PHE B N   1 
ATOM   3103 C CA  . PHE B 1 163 ? -11.701 1.589   -7.341  1.00 14.30 ? 165 PHE B CA  1 
ATOM   3104 C C   . PHE B 1 163 ? -11.027 2.792   -7.988  1.00 15.68 ? 165 PHE B C   1 
ATOM   3105 O O   . PHE B 1 163 ? -11.482 3.924   -7.831  1.00 13.79 ? 165 PHE B O   1 
ATOM   3106 C CB  . PHE B 1 163 ? -12.612 0.879   -8.361  1.00 14.00 ? 165 PHE B CB  1 
ATOM   3107 C CG  . PHE B 1 163 ? -13.781 1.711   -8.847  1.00 13.60 ? 165 PHE B CG  1 
ATOM   3108 C CD1 . PHE B 1 163 ? -14.939 1.843   -8.091  1.00 12.47 ? 165 PHE B CD1 1 
ATOM   3109 C CD2 . PHE B 1 163 ? -13.726 2.339   -10.086 1.00 13.44 ? 165 PHE B CD2 1 
ATOM   3110 C CE1 . PHE B 1 163 ? -16.011 2.582   -8.553  1.00 11.68 ? 165 PHE B CE1 1 
ATOM   3111 C CE2 . PHE B 1 163 ? -14.804 3.098   -10.555 1.00 14.56 ? 165 PHE B CE2 1 
ATOM   3112 C CZ  . PHE B 1 163 ? -15.947 3.222   -9.780  1.00 11.53 ? 165 PHE B CZ  1 
ATOM   3113 N N   . LYS B 1 164 ? -9.927  2.542   -8.698  1.00 19.58 ? 166 LYS B N   1 
ATOM   3114 C CA  . LYS B 1 164 ? -9.204  3.582   -9.426  1.00 17.58 ? 166 LYS B CA  1 
ATOM   3115 C C   . LYS B 1 164 ? -9.581  3.566   -10.900 1.00 14.80 ? 166 LYS B C   1 
ATOM   3116 O O   . LYS B 1 164 ? -9.760  2.503   -11.492 1.00 18.13 ? 166 LYS B O   1 
ATOM   3117 C CB  . LYS B 1 164 ? -7.687  3.395   -9.320  1.00 19.08 ? 166 LYS B CB  1 
ATOM   3118 C CG  . LYS B 1 164 ? -7.151  3.047   -7.949  1.00 27.39 ? 166 LYS B CG  1 
ATOM   3119 C CD  . LYS B 1 164 ? -5.622  2.946   -7.990  1.00 34.32 ? 166 LYS B CD  1 
ATOM   3120 C CE  . LYS B 1 164 ? -5.017  3.007   -6.602  1.00 40.22 ? 166 LYS B CE  1 
ATOM   3121 N NZ  . LYS B 1 164 ? -5.218  4.348   -5.996  1.00 42.69 ? 166 LYS B NZ  1 
ATOM   3122 N N   . ILE B 1 165 ? -9.679  4.749   -11.494 1.00 14.74 ? 167 ILE B N   1 
ATOM   3123 C CA  . ILE B 1 165 ? -9.760  4.895   -12.939 1.00 13.88 ? 167 ILE B CA  1 
ATOM   3124 C C   . ILE B 1 165 ? -8.547  5.697   -13.391 1.00 14.87 ? 167 ILE B C   1 
ATOM   3125 O O   . ILE B 1 165 ? -8.194  6.699   -12.766 1.00 14.85 ? 167 ILE B O   1 
ATOM   3126 C CB  . ILE B 1 165 ? -11.069 5.589   -13.370 1.00 15.64 ? 167 ILE B CB  1 
ATOM   3127 C CG1 . ILE B 1 165 ? -12.269 4.691   -13.019 1.00 14.29 ? 167 ILE B CG1 1 
ATOM   3128 C CG2 . ILE B 1 165 ? -11.011 5.971   -14.851 1.00 14.08 ? 167 ILE B CG2 1 
ATOM   3129 C CD1 . ILE B 1 165 ? -12.450 3.492   -13.946 1.00 16.90 ? 167 ILE B CD1 1 
ATOM   3130 N N   . ARG B 1 166 ? -7.928  5.272   -14.491 1.00 15.52 ? 168 ARG B N   1 
ATOM   3131 C CA  . ARG B 1 166 ? -6.756  5.932   -15.064 1.00 18.09 ? 168 ARG B CA  1 
ATOM   3132 C C   . ARG B 1 166 ? -7.173  6.657   -16.340 1.00 16.96 ? 168 ARG B C   1 
ATOM   3133 O O   . ARG B 1 166 ? -7.562  6.006   -17.314 1.00 17.81 ? 168 ARG B O   1 
ATOM   3134 C CB  . ARG B 1 166 ? -5.700  4.886   -15.383 1.00 24.33 ? 168 ARG B CB  1 
ATOM   3135 C CG  . ARG B 1 166 ? -5.079  4.241   -14.180 1.00 27.90 ? 168 ARG B CG  1 
ATOM   3136 C CD  . ARG B 1 166 ? -4.272  3.034   -14.645 1.00 34.12 ? 168 ARG B CD  1 
ATOM   3137 N NE  . ARG B 1 166 ? -2.847  3.320   -14.723 1.00 41.48 ? 168 ARG B NE  1 
ATOM   3138 C CZ  . ARG B 1 166 ? -2.065  3.502   -13.669 1.00 45.24 ? 168 ARG B CZ  1 
ATOM   3139 N NH1 . ARG B 1 166 ? -2.525  3.362   -12.435 1.00 44.15 ? 168 ARG B NH1 1 
ATOM   3140 N NH2 . ARG B 1 166 ? -0.788  3.827   -13.858 1.00 41.85 ? 168 ARG B NH2 1 
ATOM   3141 N N   . HIS B 1 167 ? -7.065  7.992   -16.353 1.00 14.92 ? 169 HIS B N   1 
ATOM   3142 C CA  . HIS B 1 167 ? -7.400  8.786   -17.538 1.00 15.15 ? 169 HIS B CA  1 
ATOM   3143 C C   . HIS B 1 167 ? -6.131  9.116   -18.322 1.00 17.02 ? 169 HIS B C   1 
ATOM   3144 O O   . HIS B 1 167 ? -5.142  9.581   -17.748 1.00 18.89 ? 169 HIS B O   1 
ATOM   3145 C CB  . HIS B 1 167 ? -8.115  10.092  -17.151 1.00 14.01 ? 169 HIS B CB  1 
ATOM   3146 C CG  . HIS B 1 167 ? -9.473  9.897   -16.540 1.00 12.06 ? 169 HIS B CG  1 
ATOM   3147 N ND1 . HIS B 1 167 ? -10.496 9.235   -17.183 1.00 14.33 ? 169 HIS B ND1 1 
ATOM   3148 C CD2 . HIS B 1 167 ? -9.963  10.252  -15.327 1.00 15.09 ? 169 HIS B CD2 1 
ATOM   3149 C CE1 . HIS B 1 167 ? -11.566 9.212   -16.407 1.00 13.07 ? 169 HIS B CE1 1 
ATOM   3150 N NE2 . HIS B 1 167 ? -11.266 9.816   -15.269 1.00 13.41 ? 169 HIS B NE2 1 
ATOM   3151 N N   . ASN B 1 168 ? -6.163  8.896   -19.629 1.00 18.36 ? 170 ASN B N   1 
ATOM   3152 C CA  . ASN B 1 168 ? -4.993  9.199   -20.449 1.00 17.19 ? 170 ASN B CA  1 
ATOM   3153 C C   . ASN B 1 168 ? -4.817  10.708  -20.577 1.00 16.60 ? 170 ASN B C   1 
ATOM   3154 O O   . ASN B 1 168 ? -5.746  11.412  -20.976 1.00 17.43 ? 170 ASN B O   1 
ATOM   3155 C CB  . ASN B 1 168 ? -5.156  8.581   -21.832 1.00 18.29 ? 170 ASN B CB  1 
ATOM   3156 C CG  . ASN B 1 168 ? -4.941  7.091   -21.821 1.00 19.86 ? 170 ASN B CG  1 
ATOM   3157 O OD1 . ASN B 1 168 ? -4.112  6.581   -21.076 1.00 17.86 ? 170 ASN B OD1 1 
ATOM   3158 N ND2 . ASN B 1 168 ? -5.719  6.380   -22.622 1.00 24.42 ? 170 ASN B ND2 1 
ATOM   3159 N N   . ILE B 1 169 ? -3.609  11.209  -20.265 1.00 16.07 ? 171 ILE B N   1 
ATOM   3160 C CA  . ILE B 1 169 ? -3.285  12.627  -20.427 1.00 17.64 ? 171 ILE B CA  1 
ATOM   3161 C C   . ILE B 1 169 ? -2.750  12.866  -21.836 1.00 19.88 ? 171 ILE B C   1 
ATOM   3162 O O   . ILE B 1 169 ? -1.964  12.068  -22.363 1.00 17.90 ? 171 ILE B O   1 
ATOM   3163 C CB  . ILE B 1 169 ? -2.262  13.091  -19.365 1.00 18.86 ? 171 ILE B CB  1 
ATOM   3164 C CG1 . ILE B 1 169 ? -2.762  12.814  -17.944 1.00 19.38 ? 171 ILE B CG1 1 
ATOM   3165 C CG2 . ILE B 1 169 ? -1.914  14.560  -19.540 1.00 19.12 ? 171 ILE B CG2 1 
ATOM   3166 N N   . GLU B 1 170 ? -3.155  13.982  -22.441 1.00 15.99 ? 172 GLU B N   1 
ATOM   3167 C CA  . GLU B 1 170 ? -2.645  14.319  -23.760 1.00 21.81 ? 172 GLU B CA  1 
ATOM   3168 C C   . GLU B 1 170 ? -1.128  14.419  -23.710 1.00 20.35 ? 172 GLU B C   1 
ATOM   3169 O O   . GLU B 1 170 ? -0.558  14.976  -22.773 1.00 22.85 ? 172 GLU B O   1 
ATOM   3170 C CB  . GLU B 1 170 ? -3.244  15.637  -24.275 1.00 20.84 ? 172 GLU B CB  1 
ATOM   3171 C CG  . GLU B 1 170 ? -4.650  15.465  -24.834 1.00 23.09 ? 172 GLU B CG  1 
ATOM   3172 C CD  . GLU B 1 170 ? -5.378  16.780  -25.091 1.00 29.06 ? 172 GLU B CD  1 
ATOM   3173 O OE1 . GLU B 1 170 ? -4.932  17.827  -24.580 1.00 27.24 ? 172 GLU B OE1 1 
ATOM   3174 O OE2 . GLU B 1 170 ? -6.426  16.749  -25.781 1.00 30.59 ? 172 GLU B OE2 1 
ATOM   3175 N N   . ASP B 1 171 ? -0.478  13.857  -24.700 1.00 22.22 ? 173 ASP B N   1 
ATOM   3176 C CA  . ASP B 1 171 ? 0.962   13.776  -24.811 1.00 23.51 ? 173 ASP B CA  1 
ATOM   3177 C C   . ASP B 1 171 ? 1.659   12.887  -23.826 1.00 24.83 ? 173 ASP B C   1 
ATOM   3178 O O   . ASP B 1 171 ? 2.839   12.913  -23.714 1.00 25.95 ? 173 ASP B O   1 
ATOM   3179 C CB  . ASP B 1 171 ? 1.607   15.115  -24.836 1.00 27.24 ? 173 ASP B CB  1 
ATOM   3180 C CG  . ASP B 1 171 ? 1.179   15.903  -25.962 1.00 30.36 ? 173 ASP B CG  1 
ATOM   3181 O OD1 . ASP B 1 171 ? 1.099   17.083  -25.784 1.00 40.60 ? 173 ASP B OD1 1 
ATOM   3182 O OD2 . ASP B 1 171 ? 0.923   15.361  -27.013 1.00 33.23 ? 173 ASP B OD2 1 
ATOM   3183 N N   . GLY B 1 172 ? 0.890   12.081  -23.135 1.00 22.39 ? 174 GLY B N   1 
ATOM   3184 C CA  . GLY B 1 172 ? 1.424   11.055  -22.298 1.00 26.14 ? 174 GLY B CA  1 
ATOM   3185 C C   . GLY B 1 172 ? 1.151   11.089  -20.829 1.00 26.73 ? 174 GLY B C   1 
ATOM   3186 O O   . GLY B 1 172 ? 0.999   12.101  -20.258 1.00 34.47 ? 174 GLY B O   1 
ATOM   3187 N N   . GLY B 1 173 ? 1.139   9.953   -20.222 1.00 27.08 ? 175 GLY B N   1 
ATOM   3188 C CA  . GLY B 1 173 ? 0.941   9.989   -18.808 1.00 33.29 ? 175 GLY B CA  1 
ATOM   3189 C C   . GLY B 1 173 ? -0.489  9.656   -18.485 1.00 25.04 ? 175 GLY B C   1 
ATOM   3190 O O   . GLY B 1 173 ? -1.312  9.576   -19.332 1.00 16.58 ? 175 GLY B O   1 
ATOM   3191 N N   . VAL B 1 174 ? -0.702  9.499   -17.197 1.00 21.87 ? 176 VAL B N   1 
ATOM   3192 C CA  . VAL B 1 174 ? -1.941  9.043   -16.647 1.00 22.30 ? 176 VAL B CA  1 
ATOM   3193 C C   . VAL B 1 174 ? -2.416  9.881   -15.480 1.00 21.48 ? 176 VAL B C   1 
ATOM   3194 O O   . VAL B 1 174 ? -1.679  10.159  -14.618 1.00 23.46 ? 176 VAL B O   1 
ATOM   3195 C CB  . VAL B 1 174 ? -1.796  7.552   -16.234 1.00 31.22 ? 176 VAL B CB  1 
ATOM   3196 C CG1 . VAL B 1 174 ? -2.486  7.292   -15.031 1.00 28.14 ? 176 VAL B CG1 1 
ATOM   3197 C CG2 . VAL B 1 174 ? -2.312  6.657   -17.323 1.00 31.05 ? 176 VAL B CG2 1 
ATOM   3198 N N   . GLN B 1 175 ? -3.676  10.238  -15.489 1.00 17.24 ? 177 GLN B N   1 
ATOM   3199 C CA  . GLN B 1 175 ? -4.316  11.052  -14.453 1.00 15.32 ? 177 GLN B CA  1 
ATOM   3200 C C   . GLN B 1 175 ? -5.207  10.130  -13.623 1.00 17.70 ? 177 GLN B C   1 
ATOM   3201 O O   . GLN B 1 175 ? -6.213  9.622   -14.122 1.00 14.11 ? 177 GLN B O   1 
ATOM   3202 C CB  . GLN B 1 175 ? -5.126  12.195  -15.072 1.00 17.82 ? 177 GLN B CB  1 
ATOM   3203 C CG  . GLN B 1 175 ? -6.100  12.864  -14.099 1.00 17.08 ? 177 GLN B CG  1 
ATOM   3204 C CD  . GLN B 1 175 ? -5.394  13.710  -13.059 1.00 18.04 ? 177 GLN B CD  1 
ATOM   3205 O OE1 . GLN B 1 175 ? -4.774  14.731  -13.379 1.00 18.85 ? 177 GLN B OE1 1 
ATOM   3206 N NE2 . GLN B 1 175 ? -5.457  13.275  -11.805 1.00 18.21 ? 177 GLN B NE2 1 
ATOM   3207 N N   . LEU B 1 176 ? -4.825  9.889   -12.369 1.00 16.90 ? 178 LEU B N   1 
ATOM   3208 C CA  . LEU B 1 176 ? -5.551  8.945   -11.530 1.00 16.90 ? 178 LEU B CA  1 
ATOM   3209 C C   . LEU B 1 176 ? -6.834  9.583   -11.009 1.00 14.39 ? 178 LEU B C   1 
ATOM   3210 O O   . LEU B 1 176 ? -6.867  10.780  -10.702 1.00 15.56 ? 178 LEU B O   1 
ATOM   3211 C CB  . LEU B 1 176 ? -4.678  8.485   -10.361 1.00 17.76 ? 178 LEU B CB  1 
ATOM   3212 C CG  . LEU B 1 176 ? -5.352  7.583   -9.318  1.00 26.36 ? 178 LEU B CG  1 
ATOM   3213 C CD1 . LEU B 1 176 ? -5.479  6.181   -9.905  1.00 29.71 ? 178 LEU B CD1 1 
ATOM   3214 C CD2 . LEU B 1 176 ? -4.578  7.547   -7.981  1.00 32.54 ? 178 LEU B CD2 1 
ATOM   3215 N N   . ALA B 1 177 ? -7.902  8.778   -10.947 1.00 13.61 ? 179 ALA B N   1 
ATOM   3216 C CA  . ALA B 1 177 ? -9.180  9.165   -10.343 1.00 11.54 ? 179 ALA B CA  1 
ATOM   3217 C C   . ALA B 1 177 ? -9.575  8.079   -9.346  1.00 13.41 ? 179 ALA B C   1 
ATOM   3218 O O   . ALA B 1 177 ? -10.059 7.022   -9.751  1.00 12.32 ? 179 ALA B O   1 
ATOM   3219 C CB  . ALA B 1 177 ? -10.260 9.357   -11.407 1.00 13.51 ? 179 ALA B CB  1 
ATOM   3220 N N   . ASP B 1 178 ? -9.389  8.361   -8.052  1.00 15.15 ? 180 ASP B N   1 
ATOM   3221 C CA  . ASP B 1 178 ? -9.670  7.428   -6.951  1.00 14.02 ? 180 ASP B CA  1 
ATOM   3222 C C   . ASP B 1 178 ? -11.140 7.553   -6.571  1.00 13.51 ? 180 ASP B C   1 
ATOM   3223 O O   . ASP B 1 178 ? -11.556 8.594   -6.062  1.00 12.83 ? 180 ASP B O   1 
ATOM   3224 C CB  . ASP B 1 178 ? -8.764  7.751   -5.755  1.00 17.52 ? 180 ASP B CB  1 
ATOM   3225 C CG  . ASP B 1 178 ? -8.656  6.601   -4.740  1.00 23.26 ? 180 ASP B CG  1 
ATOM   3226 O OD1 . ASP B 1 178 ? -9.080  5.467   -5.053  1.00 26.06 ? 180 ASP B OD1 1 
ATOM   3227 O OD2 . ASP B 1 178 ? -8.086  6.828   -3.632  1.00 22.75 ? 180 ASP B OD2 1 
ATOM   3228 N N   . HIS B 1 179 ? -11.918 6.492   -6.815  1.00 12.01 ? 181 HIS B N   1 
ATOM   3229 C CA  . HIS B 1 179 ? -13.368 6.482   -6.629  1.00 12.39 ? 181 HIS B CA  1 
ATOM   3230 C C   . HIS B 1 179 ? -13.719 5.785   -5.314  1.00 12.77 ? 181 HIS B C   1 
ATOM   3231 O O   . HIS B 1 179 ? -13.248 4.674   -5.062  1.00 14.75 ? 181 HIS B O   1 
ATOM   3232 C CB  . HIS B 1 179 ? -14.069 5.705   -7.757  1.00 10.77 ? 181 HIS B CB  1 
ATOM   3233 C CG  . HIS B 1 179 ? -14.110 6.415   -9.078  1.00 10.23 ? 181 HIS B CG  1 
ATOM   3234 N ND1 . HIS B 1 179 ? -12.968 6.768   -9.765  1.00 9.94  ? 181 HIS B ND1 1 
ATOM   3235 C CD2 . HIS B 1 179 ? -15.151 6.818   -9.846  1.00 10.76 ? 181 HIS B CD2 1 
ATOM   3236 C CE1 . HIS B 1 179 ? -13.304 7.360   -10.898 1.00 12.68 ? 181 HIS B CE1 1 
ATOM   3237 N NE2 . HIS B 1 179 ? -14.622 7.399   -10.975 1.00 10.20 ? 181 HIS B NE2 1 
ATOM   3238 N N   . TYR B 1 180 ? -14.598 6.400   -4.523  1.00 12.26 ? 182 TYR B N   1 
ATOM   3239 C CA  . TYR B 1 180 ? -15.215 5.779   -3.350  1.00 14.06 ? 182 TYR B CA  1 
ATOM   3240 C C   . TYR B 1 180 ? -16.717 5.800   -3.568  1.00 11.20 ? 182 TYR B C   1 
ATOM   3241 O O   . TYR B 1 180 ? -17.254 6.826   -3.989  1.00 14.55 ? 182 TYR B O   1 
ATOM   3242 C CB  . TYR B 1 180 ? -14.832 6.519   -2.065  1.00 13.63 ? 182 TYR B CB  1 
ATOM   3243 C CG  . TYR B 1 180 ? -13.343 6.488   -1.851  1.00 16.01 ? 182 TYR B CG  1 
ATOM   3244 C CD1 . TYR B 1 180 ? -12.509 7.391   -2.508  1.00 15.05 ? 182 TYR B CD1 1 
ATOM   3245 C CD2 . TYR B 1 180 ? -12.769 5.561   -1.000  1.00 16.60 ? 182 TYR B CD2 1 
ATOM   3246 C CE1 . TYR B 1 180 ? -11.155 7.354   -2.342  1.00 17.05 ? 182 TYR B CE1 1 
ATOM   3247 C CE2 . TYR B 1 180 ? -11.399 5.525   -0.813  1.00 21.67 ? 182 TYR B CE2 1 
ATOM   3248 C CZ  . TYR B 1 180 ? -10.602 6.425   -1.490  1.00 18.16 ? 182 TYR B CZ  1 
ATOM   3249 O OH  . TYR B 1 180 ? -9.241  6.396   -1.326  1.00 18.44 ? 182 TYR B OH  1 
ATOM   3250 N N   . GLN B 1 181 ? -17.385 4.668   -3.328  1.00 13.29 ? 183 GLN B N   1 
ATOM   3251 C CA  . GLN B 1 181 ? -18.791 4.534   -3.702  1.00 13.76 ? 183 GLN B CA  1 
ATOM   3252 C C   . GLN B 1 181 ? -19.590 3.876   -2.586  1.00 12.78 ? 183 GLN B C   1 
ATOM   3253 O O   . GLN B 1 181 ? -19.133 2.910   -1.984  1.00 13.20 ? 183 GLN B O   1 
ATOM   3254 C CB  . GLN B 1 181 ? -18.933 3.689   -4.971  1.00 12.98 ? 183 GLN B CB  1 
ATOM   3255 C CG  . GLN B 1 181 ? -20.370 3.472   -5.423  1.00 12.78 ? 183 GLN B CG  1 
ATOM   3256 C CD  . GLN B 1 181 ? -20.464 2.697   -6.733  1.00 14.73 ? 183 GLN B CD  1 
ATOM   3257 O OE1 . GLN B 1 181 ? -19.490 2.575   -7.484  1.00 12.81 ? 183 GLN B OE1 1 
ATOM   3258 N NE2 . GLN B 1 181 ? -21.651 2.179   -7.016  1.00 15.08 ? 183 GLN B NE2 1 
ATOM   3259 N N   . GLN B 1 182 ? -20.787 4.383   -2.320  1.00 13.51 ? 184 GLN B N   1 
ATOM   3260 C CA  . GLN B 1 182 ? -21.727 3.615   -1.516  1.00 17.19 ? 184 GLN B CA  1 
ATOM   3261 C C   . GLN B 1 182 ? -23.129 3.786   -2.080  1.00 17.57 ? 184 GLN B C   1 
ATOM   3262 O O   . GLN B 1 182 ? -23.512 4.876   -2.518  1.00 14.78 ? 184 GLN B O   1 
ATOM   3263 C CB  . GLN B 1 182 ? -21.675 4.010   -0.037  1.00 22.83 ? 184 GLN B CB  1 
ATOM   3264 C CG  . GLN B 1 182 ? -22.756 4.938   0.444   1.00 29.33 ? 184 GLN B CG  1 
ATOM   3265 C CD  . GLN B 1 182 ? -22.615 5.230   1.936   1.00 38.74 ? 184 GLN B CD  1 
ATOM   3266 O OE1 . GLN B 1 182 ? -21.877 4.540   2.647   1.00 41.21 ? 184 GLN B OE1 1 
ATOM   3267 N NE2 . GLN B 1 182 ? -23.307 6.265   2.409   1.00 41.97 ? 184 GLN B NE2 1 
ATOM   3268 N N   . ASN B 1 183 ? -23.882 2.692   -2.093  1.00 16.82 ? 185 ASN B N   1 
ATOM   3269 C CA  . ASN B 1 183 ? -25.253 2.687   -2.582  1.00 13.88 ? 185 ASN B CA  1 
ATOM   3270 C C   . ASN B 1 183 ? -26.181 2.194   -1.486  1.00 17.87 ? 185 ASN B C   1 
ATOM   3271 O O   . ASN B 1 183 ? -25.839 1.265   -0.756  1.00 18.71 ? 185 ASN B O   1 
ATOM   3272 C CB  . ASN B 1 183 ? -25.422 1.781   -3.799  1.00 12.92 ? 185 ASN B CB  1 
ATOM   3273 C CG  . ASN B 1 183 ? -24.676 2.290   -5.007  1.00 14.06 ? 185 ASN B CG  1 
ATOM   3274 O OD1 . ASN B 1 183 ? -23.564 2.763   -4.889  1.00 15.37 ? 185 ASN B OD1 1 
ATOM   3275 N ND2 . ASN B 1 183 ? -25.304 2.199   -6.186  1.00 14.80 ? 185 ASN B ND2 1 
ATOM   3276 N N   . THR B 1 184 ? -27.368 2.790   -1.414  1.00 18.70 ? 186 THR B N   1 
ATOM   3277 C CA  . THR B 1 184 ? -28.372 2.427   -0.422  1.00 18.47 ? 186 THR B CA  1 
ATOM   3278 C C   . THR B 1 184 ? -29.741 2.416   -1.089  1.00 19.84 ? 186 THR B C   1 
ATOM   3279 O O   . THR B 1 184 ? -30.029 3.284   -1.922  1.00 19.13 ? 186 THR B O   1 
ATOM   3280 C CB  . THR B 1 184 ? -28.360 3.411   0.762   1.00 21.96 ? 186 THR B CB  1 
ATOM   3281 O OG1 . THR B 1 184 ? -28.708 4.713   0.290   1.00 26.18 ? 186 THR B OG1 1 
ATOM   3282 C CG2 . THR B 1 184 ? -27.001 3.465   1.433   1.00 25.10 ? 186 THR B CG2 1 
ATOM   3283 N N   . PRO B 1 185 ? -30.600 1.459   -0.752  1.00 21.03 ? 187 PRO B N   1 
ATOM   3284 C CA  . PRO B 1 185 ? -31.908 1.394   -1.406  1.00 19.39 ? 187 PRO B CA  1 
ATOM   3285 C C   . PRO B 1 185 ? -32.774 2.557   -0.970  1.00 21.39 ? 187 PRO B C   1 
ATOM   3286 O O   . PRO B 1 185 ? -32.666 3.053   0.154   1.00 23.60 ? 187 PRO B O   1 
ATOM   3287 C CB  . PRO B 1 185 ? -32.501 0.069   -0.917  1.00 20.92 ? 187 PRO B CB  1 
ATOM   3288 C CG  . PRO B 1 185 ? -31.734 -0.298  0.286   1.00 24.75 ? 187 PRO B CG  1 
ATOM   3289 C CD  . PRO B 1 185 ? -30.444 0.459   0.315   1.00 21.93 ? 187 PRO B CD  1 
ATOM   3290 N N   . ILE B 1 186 ? -33.658 2.976   -1.875  1.00 19.65 ? 188 ILE B N   1 
ATOM   3291 C CA  . ILE B 1 186 ? -34.607 4.042   -1.576  1.00 22.14 ? 188 ILE B CA  1 
ATOM   3292 C C   . ILE B 1 186 ? -35.838 3.500   -0.847  1.00 27.30 ? 188 ILE B C   1 
ATOM   3293 O O   . ILE B 1 186 ? -36.344 4.129   0.090   1.00 29.16 ? 188 ILE B O   1 
ATOM   3294 C CB  . ILE B 1 186 ? -34.969 4.779   -2.882  1.00 21.42 ? 188 ILE B CB  1 
ATOM   3295 C CG1 . ILE B 1 186 ? -33.767 5.625   -3.322  1.00 19.86 ? 188 ILE B CG1 1 
ATOM   3296 C CG2 . ILE B 1 186 ? -36.261 5.609   -2.734  1.00 20.70 ? 188 ILE B CG2 1 
ATOM   3297 C CD1 . ILE B 1 186 ? -33.919 6.329   -4.648  1.00 19.18 ? 188 ILE B CD1 1 
ATOM   3298 N N   . GLY B 1 187 ? -36.319 2.324   -1.233  1.00 26.04 ? 189 GLY B N   1 
ATOM   3299 C CA  . GLY B 1 187 ? -37.493 1.758   -0.600  1.00 37.89 ? 189 GLY B CA  1 
ATOM   3300 C C   . GLY B 1 187 ? -37.237 1.271   0.824   1.00 42.93 ? 189 GLY B C   1 
ATOM   3301 O O   . GLY B 1 187 ? -36.185 1.485   1.431   1.00 37.25 ? 189 GLY B O   1 
ATOM   3302 N N   . ASP B 1 188 ? -38.266 0.607   1.368   1.00 50.54 ? 190 ASP B N   1 
ATOM   3303 C CA  . ASP B 1 188 ? -38.179 -0.113  2.633   1.00 49.30 ? 190 ASP B CA  1 
ATOM   3304 C C   . ASP B 1 188 ? -38.205 -1.622  2.474   1.00 52.27 ? 190 ASP B C   1 
ATOM   3305 O O   . ASP B 1 188 ? -37.842 -2.329  3.419   1.00 57.06 ? 190 ASP B O   1 
ATOM   3306 C CB  . ASP B 1 188 ? -39.334 0.273   3.569   1.00 54.55 ? 190 ASP B CB  1 
ATOM   3307 C CG  . ASP B 1 188 ? -39.344 1.743   3.915   1.00 56.12 ? 190 ASP B CG  1 
ATOM   3308 O OD1 . ASP B 1 188 ? -38.562 2.146   4.803   1.00 59.04 ? 190 ASP B OD1 1 
ATOM   3309 O OD2 . ASP B 1 188 ? -40.152 2.488   3.320   1.00 57.81 ? 190 ASP B OD2 1 
ATOM   3310 N N   . GLY B 1 189 ? -38.645 -2.128  1.323   1.00 53.12 ? 191 GLY B N   1 
ATOM   3311 C CA  . GLY B 1 189 ? -38.766 -3.547  1.104   1.00 53.89 ? 191 GLY B CA  1 
ATOM   3312 C C   . GLY B 1 189 ? -37.431 -4.251  1.211   1.00 57.90 ? 191 GLY B C   1 
ATOM   3313 O O   . GLY B 1 189 ? -36.367 -3.629  1.119   1.00 59.25 ? 191 GLY B O   1 
ATOM   3314 N N   . PRO B 1 190 ? -37.461 -5.568  1.413   1.00 60.52 ? 192 PRO B N   1 
ATOM   3315 C CA  . PRO B 1 190 ? -36.205 -6.319  1.496   1.00 59.19 ? 192 PRO B CA  1 
ATOM   3316 C C   . PRO B 1 190 ? -35.461 -6.265  0.171   1.00 55.73 ? 192 PRO B C   1 
ATOM   3317 O O   . PRO B 1 190 ? -36.050 -6.066  -0.894  1.00 55.84 ? 192 PRO B O   1 
ATOM   3318 C CB  . PRO B 1 190 ? -36.661 -7.743  1.832   1.00 59.74 ? 192 PRO B CB  1 
ATOM   3319 C CG  . PRO B 1 190 ? -38.045 -7.830  1.265   1.00 61.51 ? 192 PRO B CG  1 
ATOM   3320 C CD  . PRO B 1 190 ? -38.642 -6.451  1.419   1.00 57.84 ? 192 PRO B CD  1 
ATOM   3321 N N   . VAL B 1 191 ? -34.144 -6.419  0.249   1.00 54.92 ? 193 VAL B N   1 
ATOM   3322 C CA  . VAL B 1 191 ? -33.303 -6.387  -0.936  1.00 50.20 ? 193 VAL B CA  1 
ATOM   3323 C C   . VAL B 1 191 ? -32.295 -7.520  -0.838  1.00 53.69 ? 193 VAL B C   1 
ATOM   3324 O O   . VAL B 1 191 ? -31.916 -7.952  0.256   1.00 54.00 ? 193 VAL B O   1 
ATOM   3325 C CB  . VAL B 1 191 ? -32.595 -5.023  -1.108  1.00 52.33 ? 193 VAL B CB  1 
ATOM   3326 C CG1 . VAL B 1 191 ? -33.545 -4.009  -1.738  1.00 45.61 ? 193 VAL B CG1 1 
ATOM   3327 C CG2 . VAL B 1 191 ? -32.072 -4.515  0.220   1.00 45.92 ? 193 VAL B CG2 1 
ATOM   3328 N N   . LEU B 1 192 ? -31.885 -8.019  -2.000  1.00 52.30 ? 194 LEU B N   1 
ATOM   3329 C CA  . LEU B 1 192 ? -30.857 -9.043  -2.078  1.00 50.40 ? 194 LEU B CA  1 
ATOM   3330 C C   . LEU B 1 192 ? -29.491 -8.396  -1.911  1.00 49.01 ? 194 LEU B C   1 
ATOM   3331 O O   . LEU B 1 192 ? -29.153 -7.453  -2.635  1.00 46.79 ? 194 LEU B O   1 
ATOM   3332 C CB  . LEU B 1 192 ? -30.931 -9.762  -3.426  1.00 53.17 ? 194 LEU B CB  1 
ATOM   3333 C CG  . LEU B 1 192 ? -32.178 -10.588 -3.756  1.00 54.89 ? 194 LEU B CG  1 
ATOM   3334 C CD1 . LEU B 1 192 ? -32.096 -11.124 -5.180  1.00 48.42 ? 194 LEU B CD1 1 
ATOM   3335 C CD2 . LEU B 1 192 ? -32.368 -11.726 -2.755  1.00 58.15 ? 194 LEU B CD2 1 
ATOM   3336 N N   . LEU B 1 193 ? -28.704 -8.892  -0.960  1.00 47.12 ? 195 LEU B N   1 
ATOM   3337 C CA  . LEU B 1 193 ? -27.338 -8.415  -0.822  1.00 44.10 ? 195 LEU B CA  1 
ATOM   3338 C C   . LEU B 1 193 ? -26.380 -9.470  -1.346  1.00 44.69 ? 195 LEU B C   1 
ATOM   3339 O O   . LEU B 1 193 ? -26.353 -10.600 -0.829  1.00 43.99 ? 195 LEU B O   1 
ATOM   3340 C CB  . LEU B 1 193 ? -27.016 -8.061  0.626   1.00 45.59 ? 195 LEU B CB  1 
ATOM   3341 C CG  . LEU B 1 193 ? -27.991 -7.020  1.171   1.00 43.33 ? 195 LEU B CG  1 
ATOM   3342 C CD1 . LEU B 1 193 ? -28.325 -7.289  2.633   1.00 45.85 ? 195 LEU B CD1 1 
ATOM   3343 C CD2 . LEU B 1 193 ? -27.432 -5.629  0.974   1.00 42.73 ? 195 LEU B CD2 1 
ATOM   3344 N N   . PRO B 1 194 ? -25.599 -9.147  -2.372  1.00 43.14 ? 196 PRO B N   1 
ATOM   3345 C CA  . PRO B 1 194 ? -24.694 -10.137 -2.958  1.00 43.12 ? 196 PRO B CA  1 
ATOM   3346 C C   . PRO B 1 194 ? -23.615 -10.561 -1.985  1.00 39.59 ? 196 PRO B C   1 
ATOM   3347 O O   . PRO B 1 194 ? -23.281 -9.852  -1.033  1.00 39.16 ? 196 PRO B O   1 
ATOM   3348 C CB  . PRO B 1 194 ? -24.070 -9.378  -4.135  1.00 41.41 ? 196 PRO B CB  1 
ATOM   3349 C CG  . PRO B 1 194 ? -24.110 -7.945  -3.701  1.00 36.23 ? 196 PRO B CG  1 
ATOM   3350 C CD  . PRO B 1 194 ? -25.453 -7.831  -3.020  1.00 40.13 ? 196 PRO B CD  1 
ATOM   3351 N N   . ASP B 1 195 ? -23.039 -11.727 -2.252  1.00 39.22 ? 197 ASP B N   1 
ATOM   3352 C CA  . ASP B 1 195 ? -21.657 -11.865 -1.852  1.00 40.79 ? 197 ASP B CA  1 
ATOM   3353 C C   . ASP B 1 195 ? -20.806 -10.975 -2.741  1.00 33.91 ? 197 ASP B C   1 
ATOM   3354 O O   . ASP B 1 195 ? -21.202 -10.593 -3.847  1.00 32.91 ? 197 ASP B O   1 
ATOM   3355 C CB  . ASP B 1 195 ? -21.161 -13.317 -1.882  1.00 46.14 ? 197 ASP B CB  1 
ATOM   3356 C CG  . ASP B 1 195 ? -22.222 -14.318 -1.464  1.00 51.84 ? 197 ASP B CG  1 
ATOM   3357 O OD1 . ASP B 1 195 ? -22.544 -14.347 -0.259  1.00 56.59 ? 197 ASP B OD1 1 
ATOM   3358 O OD2 . ASP B 1 195 ? -22.641 -15.152 -2.282  1.00 56.99 ? 197 ASP B OD2 1 
ATOM   3359 N N   . ASN B 1 196 ? -19.659 -10.590 -2.202  1.00 32.41 ? 198 ASN B N   1 
ATOM   3360 C CA  . ASN B 1 196 ? -18.735 -9.729  -2.908  1.00 28.74 ? 198 ASN B CA  1 
ATOM   3361 C C   . ASN B 1 196 ? -18.439 -10.309 -4.285  1.00 28.49 ? 198 ASN B C   1 
ATOM   3362 O O   . ASN B 1 196 ? -18.326 -11.526 -4.454  1.00 26.71 ? 198 ASN B O   1 
ATOM   3363 C CB  . ASN B 1 196 ? -17.470 -9.592  -2.065  1.00 32.06 ? 198 ASN B CB  1 
ATOM   3364 C CG  . ASN B 1 196 ? -17.756 -8.997  -0.686  1.00 30.27 ? 198 ASN B CG  1 
ATOM   3365 O OD1 . ASN B 1 196 ? -18.900 -8.660  -0.370  1.00 31.20 ? 198 ASN B OD1 1 
ATOM   3366 N ND2 . ASN B 1 196 ? -16.725 -8.893  0.143   1.00 30.72 ? 198 ASN B ND2 1 
ATOM   3367 N N   . HIS B 1 197 ? -18.376 -9.437  -5.285  1.00 24.44 ? 199 HIS B N   1 
ATOM   3368 C CA  . HIS B 1 197 ? -18.145 -9.880  -6.653  1.00 21.41 ? 199 HIS B CA  1 
ATOM   3369 C C   . HIS B 1 197 ? -17.652 -8.687  -7.451  1.00 19.54 ? 199 HIS B C   1 
ATOM   3370 O O   . HIS B 1 197 ? -17.640 -7.554  -6.966  1.00 19.39 ? 199 HIS B O   1 
ATOM   3371 C CB  . HIS B 1 197 ? -19.411 -10.470 -7.276  1.00 20.46 ? 199 HIS B CB  1 
ATOM   3372 C CG  . HIS B 1 197 ? -20.502 -9.466  -7.463  1.00 25.71 ? 199 HIS B CG  1 
ATOM   3373 N ND1 . HIS B 1 197 ? -21.273 -8.999  -6.419  1.00 26.87 ? 199 HIS B ND1 1 
ATOM   3374 C CD2 . HIS B 1 197 ? -20.922 -8.802  -8.566  1.00 23.24 ? 199 HIS B CD2 1 
ATOM   3375 C CE1 . HIS B 1 197 ? -22.136 -8.109  -6.877  1.00 26.79 ? 199 HIS B CE1 1 
ATOM   3376 N NE2 . HIS B 1 197 ? -21.940 -7.967  -8.175  1.00 23.64 ? 199 HIS B NE2 1 
ATOM   3377 N N   . TYR B 1 198 ? -17.234 -8.960  -8.681  1.00 19.37 ? 200 TYR B N   1 
ATOM   3378 C CA  . TYR B 1 198 ? -16.726 -7.926  -9.569  1.00 19.70 ? 200 TYR B CA  1 
ATOM   3379 C C   . TYR B 1 198 ? -17.742 -7.564  -10.643 1.00 16.73 ? 200 TYR B C   1 
ATOM   3380 O O   . TYR B 1 198 ? -18.542 -8.392  -11.077 1.00 17.83 ? 200 TYR B O   1 
ATOM   3381 C CB  . TYR B 1 198 ? -15.437 -8.356  -10.271 1.00 19.98 ? 200 TYR B CB  1 
ATOM   3382 C CG  . TYR B 1 198 ? -14.231 -8.483  -9.387  1.00 21.02 ? 200 TYR B CG  1 
ATOM   3383 C CD1 . TYR B 1 198 ? -13.924 -9.688  -8.764  1.00 28.75 ? 200 TYR B CD1 1 
ATOM   3384 C CD2 . TYR B 1 198 ? -13.420 -7.388  -9.137  1.00 22.05 ? 200 TYR B CD2 1 
ATOM   3385 C CE1 . TYR B 1 198 ? -12.815 -9.806  -7.950  1.00 29.21 ? 200 TYR B CE1 1 
ATOM   3386 C CE2 . TYR B 1 198 ? -12.313 -7.496  -8.304  1.00 27.99 ? 200 TYR B CE2 1 
ATOM   3387 C CZ  . TYR B 1 198 ? -12.020 -8.710  -7.720  1.00 28.33 ? 200 TYR B CZ  1 
ATOM   3388 O OH  . TYR B 1 198 ? -10.923 -8.828  -6.897  1.00 39.31 ? 200 TYR B OH  1 
ATOM   3389 N N   . LEU B 1 199 ? -17.663 -6.316  -11.099 1.00 16.39 ? 201 LEU B N   1 
ATOM   3390 C CA  . LEU B 1 199 ? -18.277 -5.862  -12.341 1.00 12.62 ? 201 LEU B CA  1 
ATOM   3391 C C   . LEU B 1 199 ? -17.165 -5.487  -13.302 1.00 14.12 ? 201 LEU B C   1 
ATOM   3392 O O   . LEU B 1 199 ? -16.280 -4.705  -12.944 1.00 15.03 ? 201 LEU B O   1 
ATOM   3393 C CB  . LEU B 1 199 ? -19.172 -4.647  -12.104 1.00 15.18 ? 201 LEU B CB  1 
ATOM   3394 C CG  . LEU B 1 199 ? -20.378 -4.856  -11.194 1.00 15.75 ? 201 LEU B CG  1 
ATOM   3395 C CD1 . LEU B 1 199 ? -21.127 -3.513  -11.112 1.00 17.10 ? 201 LEU B CD1 1 
ATOM   3396 C CD2 . LEU B 1 199 ? -21.261 -5.957  -11.749 1.00 18.70 ? 201 LEU B CD2 1 
ATOM   3397 N N   . PHE B 1 200 ? -17.217 -6.031  -14.514 1.00 13.65 ? 202 PHE B N   1 
ATOM   3398 C CA  . PHE B 1 200 ? -16.223 -5.783  -15.554 1.00 13.17 ? 202 PHE B CA  1 
ATOM   3399 C C   . PHE B 1 200 ? -16.878 -4.956  -16.646 1.00 15.34 ? 202 PHE B C   1 
ATOM   3400 O O   . PHE B 1 200 ? -17.930 -5.342  -17.160 1.00 14.91 ? 202 PHE B O   1 
ATOM   3401 C CB  . PHE B 1 200 ? -15.711 -7.114  -16.112 1.00 15.26 ? 202 PHE B CB  1 
ATOM   3402 C CG  . PHE B 1 200 ? -14.866 -7.871  -15.131 1.00 15.92 ? 202 PHE B CG  1 
ATOM   3403 C CD1 . PHE B 1 200 ? -13.542 -7.533  -14.924 1.00 16.81 ? 202 PHE B CD1 1 
ATOM   3404 C CD2 . PHE B 1 200 ? -15.436 -8.848  -14.327 1.00 17.29 ? 202 PHE B CD2 1 
ATOM   3405 C CE1 . PHE B 1 200 ? -12.773 -8.220  -13.985 1.00 15.49 ? 202 PHE B CE1 1 
ATOM   3406 C CE2 . PHE B 1 200 ? -14.679 -9.524  -13.391 1.00 17.38 ? 202 PHE B CE2 1 
ATOM   3407 C CZ  . PHE B 1 200 ? -13.345 -9.193  -13.214 1.00 16.96 ? 202 PHE B CZ  1 
ATOM   3408 N N   . THR B 1 201 ? -16.262 -3.820  -16.996 1.00 17.21 ? 203 THR B N   1 
ATOM   3409 C CA  . THR B 1 201 ? -16.853 -2.887  -17.947 1.00 14.65 ? 203 THR B CA  1 
ATOM   3410 C C   . THR B 1 201 ? -15.926 -2.624  -19.128 1.00 14.98 ? 203 THR B C   1 
ATOM   3411 O O   . THR B 1 201 ? -14.699 -2.554  -18.978 1.00 12.72 ? 203 THR B O   1 
ATOM   3412 C CB  . THR B 1 201 ? -17.217 -1.545  -17.274 1.00 14.76 ? 203 THR B CB  1 
ATOM   3413 O OG1 . THR B 1 201 ? -18.001 -1.779  -16.099 1.00 15.86 ? 203 THR B OG1 1 
ATOM   3414 C CG2 . THR B 1 201 ? -17.972 -0.612  -18.239 1.00 16.05 ? 203 THR B CG2 1 
ATOM   3415 N N   . THR B 1 202 ? -16.524 -2.475  -20.309 1.00 13.79 ? 204 THR B N   1 
ATOM   3416 C CA  . THR B 1 202 ? -15.832 -1.899  -21.458 1.00 14.37 ? 204 THR B CA  1 
ATOM   3417 C C   . THR B 1 202 ? -16.620 -0.688  -21.937 1.00 13.99 ? 204 THR B C   1 
ATOM   3418 O O   . THR B 1 202 ? -17.840 -0.764  -22.110 1.00 14.04 ? 204 THR B O   1 
ATOM   3419 C CB  . THR B 1 202 ? -15.628 -2.911  -22.600 1.00 17.12 ? 204 THR B CB  1 
ATOM   3420 O OG1 . THR B 1 202 ? -14.980 -2.241  -23.697 1.00 17.39 ? 204 THR B OG1 1 
ATOM   3421 C CG2 . THR B 1 202 ? -16.927 -3.493  -23.083 1.00 17.50 ? 204 THR B CG2 1 
ATOM   3422 N N   . SER B 1 203 ? -15.926 0.431   -22.124 1.00 13.65 ? 205 SER B N   1 
ATOM   3423 C CA  . SER B 1 203 ? -16.545 1.679   -22.559 1.00 13.46 ? 205 SER B CA  1 
ATOM   3424 C C   . SER B 1 203 ? -15.856 2.165   -23.820 1.00 18.15 ? 205 SER B C   1 
ATOM   3425 O O   . SER B 1 203 ? -14.623 2.195   -23.873 1.00 18.94 ? 205 SER B O   1 
ATOM   3426 C CB  . SER B 1 203 ? -16.423 2.752   -21.472 1.00 12.91 ? 205 SER B CB  1 
ATOM   3427 O OG  . SER B 1 203 ? -16.910 2.247   -20.248 1.00 16.62 ? 205 SER B OG  1 
ATOM   3428 N N   . THR B 1 204 ? -16.632 2.559   -24.826 1.00 14.24 ? 206 THR B N   1 
ATOM   3429 C CA  . THR B 1 204 ? -16.041 3.221   -25.981 1.00 13.15 ? 206 THR B CA  1 
ATOM   3430 C C   . THR B 1 204 ? -16.732 4.556   -26.200 1.00 14.42 ? 206 THR B C   1 
ATOM   3431 O O   . THR B 1 204 ? -17.957 4.613   -26.292 1.00 13.71 ? 206 THR B O   1 
ATOM   3432 C CB  . THR B 1 204 ? -16.133 2.363   -27.236 1.00 18.71 ? 206 THR B CB  1 
ATOM   3433 O OG1 . THR B 1 204 ? -17.467 2.425   -27.741 1.00 30.47 ? 206 THR B OG1 1 
ATOM   3434 C CG2 . THR B 1 204 ? -15.747 0.923   -26.940 1.00 10.42 ? 206 THR B CG2 1 
ATOM   3435 N N   . LEU B 1 205 ? -15.940 5.617   -26.287 1.00 13.04 ? 207 LEU B N   1 
ATOM   3436 C CA  . LEU B 1 205 ? -16.451 6.974   -26.449 1.00 12.87 ? 207 LEU B CA  1 
ATOM   3437 C C   . LEU B 1 205 ? -16.362 7.370   -27.913 1.00 13.43 ? 207 LEU B C   1 
ATOM   3438 O O   . LEU B 1 205 ? -15.357 7.096   -28.570 1.00 15.43 ? 207 LEU B O   1 
ATOM   3439 C CB  . LEU B 1 205 ? -15.640 7.960   -25.609 1.00 13.64 ? 207 LEU B CB  1 
ATOM   3440 C CG  . LEU B 1 205 ? -15.326 7.567   -24.164 1.00 15.82 ? 207 LEU B CG  1 
ATOM   3441 C CD1 . LEU B 1 205 ? -14.861 8.793   -23.402 1.00 13.88 ? 207 LEU B CD1 1 
ATOM   3442 C CD2 . LEU B 1 205 ? -16.508 6.915   -23.512 1.00 15.90 ? 207 LEU B CD2 1 
ATOM   3443 N N   . SER B 1 206 ? -17.405 8.012   -28.432 1.00 14.77 ? 208 SER B N   1 
ATOM   3444 C CA  . SER B 1 206 ? -17.361 8.452   -29.829 1.00 12.82 ? 208 SER B CA  1 
ATOM   3445 C C   . SER B 1 206 ? -18.126 9.761   -29.959 1.00 17.20 ? 208 SER B C   1 
ATOM   3446 O O   . SER B 1 206 ? -18.629 10.310  -28.973 1.00 14.57 ? 208 SER B O   1 
ATOM   3447 C CB  . SER B 1 206 ? -17.935 7.391   -30.779 1.00 14.38 ? 208 SER B CB  1 
ATOM   3448 O OG  . SER B 1 206 ? -19.251 7.045   -30.412 1.00 13.40 ? 208 SER B OG  1 
ATOM   3449 N N   . LYS B 1 207 ? -18.225 10.257  -31.195 1.00 15.47 ? 209 LYS B N   1 
ATOM   3450 C CA  . LYS B 1 207 ? -18.956 11.483  -31.486 1.00 17.21 ? 209 LYS B CA  1 
ATOM   3451 C C   . LYS B 1 207 ? -20.034 11.229  -32.533 1.00 22.02 ? 209 LYS B C   1 
ATOM   3452 O O   . LYS B 1 207 ? -19.899 10.351  -33.395 1.00 19.06 ? 209 LYS B O   1 
ATOM   3453 C CB  . LYS B 1 207 ? -18.021 12.593  -31.982 1.00 16.61 ? 209 LYS B CB  1 
ATOM   3454 C CG  . LYS B 1 207 ? -16.922 12.973  -31.018 1.00 18.85 ? 209 LYS B CG  1 
ATOM   3455 C CD  . LYS B 1 207 ? -17.477 13.767  -29.834 1.00 15.21 ? 209 LYS B CD  1 
ATOM   3456 C CE  . LYS B 1 207 ? -16.354 14.330  -28.997 1.00 16.02 ? 209 LYS B CE  1 
ATOM   3457 N NZ  . LYS B 1 207 ? -16.884 15.022  -27.778 1.00 18.16 ? 209 LYS B NZ  1 
ATOM   3458 N N   . ASP B 1 208 ? -21.112 12.008  -32.437 1.00 18.89 ? 210 ASP B N   1 
ATOM   3459 C CA  . ASP B 1 208 ? -22.194 11.989  -33.412 1.00 19.28 ? 210 ASP B CA  1 
ATOM   3460 C C   . ASP B 1 208 ? -21.872 13.008  -34.493 1.00 23.85 ? 210 ASP B C   1 
ATOM   3461 O O   . ASP B 1 208 ? -21.790 14.209  -34.192 1.00 21.39 ? 210 ASP B O   1 
ATOM   3462 C CB  . ASP B 1 208 ? -23.524 12.316  -32.729 1.00 21.46 ? 210 ASP B CB  1 
ATOM   3463 C CG  . ASP B 1 208 ? -24.703 12.502  -33.698 1.00 22.51 ? 210 ASP B CG  1 
ATOM   3464 O OD1 . ASP B 1 208 ? -24.565 12.445  -34.939 1.00 24.94 ? 210 ASP B OD1 1 
ATOM   3465 O OD2 . ASP B 1 208 ? -25.821 12.688  -33.179 1.00 21.12 ? 210 ASP B OD2 1 
ATOM   3466 N N   . PRO B 1 209 ? -21.668 12.587  -35.743 1.00 25.98 ? 211 PRO B N   1 
ATOM   3467 C CA  . PRO B 1 209 ? -21.188 13.528  -36.764 1.00 25.11 ? 211 PRO B CA  1 
ATOM   3468 C C   . PRO B 1 209 ? -22.175 14.635  -37.080 1.00 24.50 ? 211 PRO B C   1 
ATOM   3469 O O   . PRO B 1 209 ? -21.767 15.660  -37.637 1.00 30.01 ? 211 PRO B O   1 
ATOM   3470 C CB  . PRO B 1 209 ? -20.938 12.643  -37.992 1.00 26.44 ? 211 PRO B CB  1 
ATOM   3471 C CG  . PRO B 1 209 ? -21.507 11.321  -37.690 1.00 29.26 ? 211 PRO B CG  1 
ATOM   3472 C CD  . PRO B 1 209 ? -21.992 11.260  -36.276 1.00 26.05 ? 211 PRO B CD  1 
ATOM   3473 N N   . ASN B 1 210 ? -23.445 14.470  -36.741 1.00 25.63 ? 212 ASN B N   1 
ATOM   3474 C CA  . ASN B 1 210 ? -24.473 15.461  -37.021 1.00 26.71 ? 212 ASN B CA  1 
ATOM   3475 C C   . ASN B 1 210 ? -24.736 16.387  -35.839 1.00 27.63 ? 212 ASN B C   1 
ATOM   3476 O O   . ASN B 1 210 ? -25.594 17.268  -35.943 1.00 24.72 ? 212 ASN B O   1 
ATOM   3477 C CB  . ASN B 1 210 ? -25.765 14.741  -37.409 1.00 29.48 ? 212 ASN B CB  1 
ATOM   3478 C CG  . ASN B 1 210 ? -25.696 14.143  -38.803 1.00 33.85 ? 212 ASN B CG  1 
ATOM   3479 O OD1 . ASN B 1 210 ? -24.851 14.519  -39.609 1.00 33.71 ? 212 ASN B OD1 1 
ATOM   3480 N ND2 . ASN B 1 210 ? -26.516 13.130  -39.047 1.00 38.46 ? 212 ASN B ND2 1 
ATOM   3481 N N   . GLU B 1 211 ? -24.037 16.200  -34.717 1.00 23.01 ? 213 GLU B N   1 
ATOM   3482 C CA  . GLU B 1 211 ? -24.333 16.921  -33.484 1.00 20.49 ? 213 GLU B CA  1 
ATOM   3483 C C   . GLU B 1 211 ? -23.379 18.099  -33.328 1.00 21.16 ? 213 GLU B C   1 
ATOM   3484 O O   . GLU B 1 211 ? -22.167 17.912  -33.208 1.00 22.55 ? 213 GLU B O   1 
ATOM   3485 C CB  . GLU B 1 211 ? -24.243 15.985  -32.277 1.00 20.37 ? 213 GLU B CB  1 
ATOM   3486 C CG  . GLU B 1 211 ? -24.511 16.673  -30.942 1.00 18.16 ? 213 GLU B CG  1 
ATOM   3487 C CD  . GLU B 1 211 ? -25.879 17.305  -30.913 1.00 20.29 ? 213 GLU B CD  1 
ATOM   3488 O OE1 . GLU B 1 211 ? -26.880 16.566  -30.877 1.00 19.08 ? 213 GLU B OE1 1 
ATOM   3489 O OE2 . GLU B 1 211 ? -25.945 18.553  -30.945 1.00 24.39 ? 213 GLU B OE2 1 
ATOM   3490 N N   . LYS B 1 212 ? -23.927 19.310  -33.310 1.00 21.76 ? 214 LYS B N   1 
ATOM   3491 C CA  . LYS B 1 212 ? -23.113 20.502  -33.118 1.00 22.41 ? 214 LYS B CA  1 
ATOM   3492 C C   . LYS B 1 212 ? -22.856 20.815  -31.648 1.00 18.11 ? 214 LYS B C   1 
ATOM   3493 O O   . LYS B 1 212 ? -21.914 21.546  -31.336 1.00 21.46 ? 214 LYS B O   1 
ATOM   3494 C CB  . LYS B 1 212 ? -23.788 21.714  -33.769 1.00 26.54 ? 214 LYS B CB  1 
ATOM   3495 C CG  . LYS B 1 212 ? -23.646 21.828  -35.304 1.00 32.12 ? 214 LYS B CG  1 
ATOM   3496 C CD  . LYS B 1 212 ? -22.322 21.298  -35.877 1.00 34.89 ? 214 LYS B CD  1 
ATOM   3497 C CE  . LYS B 1 212 ? -22.500 19.881  -36.474 1.00 37.83 ? 214 LYS B CE  1 
ATOM   3498 N NZ  . LYS B 1 212 ? -21.243 19.261  -36.996 1.00 38.82 ? 214 LYS B NZ  1 
ATOM   3499 N N   . ARG B 1 213 ? -23.643 20.269  -30.739 1.00 17.45 ? 215 ARG B N   1 
ATOM   3500 C CA  . ARG B 1 213 ? -23.454 20.575  -29.330 1.00 19.14 ? 215 ARG B CA  1 
ATOM   3501 C C   . ARG B 1 213 ? -22.294 19.751  -28.770 1.00 19.19 ? 215 ARG B C   1 
ATOM   3502 O O   . ARG B 1 213 ? -21.914 18.732  -29.342 1.00 17.14 ? 215 ARG B O   1 
ATOM   3503 C CB  . ARG B 1 213 ? -24.754 20.306  -28.583 1.00 18.27 ? 215 ARG B CB  1 
ATOM   3504 C CG  . ARG B 1 213 ? -25.758 21.420  -28.862 1.00 23.59 ? 215 ARG B CG  1 
ATOM   3505 C CD  . ARG B 1 213 ? -27.181 21.163  -28.402 1.00 28.06 ? 215 ARG B CD  1 
ATOM   3506 N NE  . ARG B 1 213 ? -27.829 20.015  -29.026 1.00 30.42 ? 215 ARG B NE  1 
ATOM   3507 C CZ  . ARG B 1 213 ? -28.895 19.414  -28.514 1.00 35.16 ? 215 ARG B CZ  1 
ATOM   3508 N NH1 . ARG B 1 213 ? -29.438 19.826  -27.378 1.00 37.81 ? 215 ARG B NH1 1 
ATOM   3509 N NH2 . ARG B 1 213 ? -29.439 18.386  -29.161 1.00 41.43 ? 215 ARG B NH2 1 
ATOM   3510 N N   . ASP B 1 214 ? -21.680 20.245  -27.691 1.00 16.14 ? 216 ASP B N   1 
ATOM   3511 C CA  . ASP B 1 214 ? -20.688 19.459  -26.955 1.00 13.95 ? 216 ASP B CA  1 
ATOM   3512 C C   . ASP B 1 214 ? -21.371 18.204  -26.436 1.00 16.63 ? 216 ASP B C   1 
ATOM   3513 O O   . ASP B 1 214 ? -22.408 18.290  -25.780 1.00 14.52 ? 216 ASP B O   1 
ATOM   3514 C CB  . ASP B 1 214 ? -20.112 20.280  -25.792 1.00 13.58 ? 216 ASP B CB  1 
ATOM   3515 C CG  . ASP B 1 214 ? -18.749 19.801  -25.323 1.00 17.38 ? 216 ASP B CG  1 
ATOM   3516 O OD1 . ASP B 1 214 ? -18.208 18.812  -25.860 1.00 17.06 ? 216 ASP B OD1 1 
ATOM   3517 O OD2 . ASP B 1 214 ? -18.214 20.401  -24.361 1.00 18.90 ? 216 ASP B OD2 1 
ATOM   3518 N N   . HIS B 1 215 ? -20.803 17.035  -26.733 1.00 13.84 ? 217 HIS B N   1 
ATOM   3519 C CA  . HIS B 1 215 ? -21.545 15.807  -26.485 1.00 12.08 ? 217 HIS B CA  1 
ATOM   3520 C C   . HIS B 1 215 ? -20.595 14.613  -26.414 1.00 11.15 ? 217 HIS B C   1 
ATOM   3521 O O   . HIS B 1 215 ? -19.421 14.696  -26.783 1.00 14.17 ? 217 HIS B O   1 
ATOM   3522 C CB  . HIS B 1 215 ? -22.581 15.575  -27.584 1.00 12.73 ? 217 HIS B CB  1 
ATOM   3523 C CG  . HIS B 1 215 ? -21.962 15.160  -28.882 1.00 15.63 ? 217 HIS B CG  1 
ATOM   3524 N ND1 . HIS B 1 215 ? -21.285 16.042  -29.695 1.00 16.28 ? 217 HIS B ND1 1 
ATOM   3525 C CD2 . HIS B 1 215 ? -21.865 13.948  -29.474 1.00 16.07 ? 217 HIS B CD2 1 
ATOM   3526 C CE1 . HIS B 1 215 ? -20.819 15.397  -30.749 1.00 17.94 ? 217 HIS B CE1 1 
ATOM   3527 N NE2 . HIS B 1 215 ? -21.155 14.124  -30.638 1.00 15.78 ? 217 HIS B NE2 1 
ATOM   3528 N N   . MET B 1 216 ? -21.143 13.495  -25.923 1.00 12.59 ? 218 MET B N   1 
ATOM   3529 C CA  . MET B 1 216 ? -20.476 12.193  -25.816 1.00 13.02 ? 218 MET B CA  1 
ATOM   3530 C C   . MET B 1 216 ? -21.418 11.090  -26.247 1.00 11.67 ? 218 MET B C   1 
ATOM   3531 O O   . MET B 1 216 ? -22.470 10.926  -25.633 1.00 12.72 ? 218 MET B O   1 
ATOM   3532 C CB  . MET B 1 216 ? -20.043 11.880  -24.383 1.00 11.87 ? 218 MET B CB  1 
ATOM   3533 C CG  . MET B 1 216 ? -19.123 10.674  -24.312 1.00 13.36 ? 218 MET B CG  1 
ATOM   3534 S SD  . MET B 1 216 ? -18.401 10.437  -22.679 1.00 12.67 ? 218 MET B SD  1 
ATOM   3535 C CE  . MET B 1 216 ? -19.851 10.512  -21.607 1.00 12.87 ? 218 MET B CE  1 
ATOM   3536 N N   . VAL B 1 217 ? -21.022 10.291  -27.246 1.00 13.94 ? 219 VAL B N   1 
ATOM   3537 C CA  . VAL B 1 217 ? -21.705 9.037   -27.548 1.00 13.73 ? 219 VAL B CA  1 
ATOM   3538 C C   . VAL B 1 217 ? -20.958 7.914   -26.854 1.00 14.60 ? 219 VAL B C   1 
ATOM   3539 O O   . VAL B 1 217 ? -19.723 7.869   -26.897 1.00 13.61 ? 219 VAL B O   1 
ATOM   3540 C CB  . VAL B 1 217 ? -21.793 8.772   -29.063 1.00 14.97 ? 219 VAL B CB  1 
ATOM   3541 C CG1 . VAL B 1 217 ? -22.482 7.422   -29.323 1.00 14.40 ? 219 VAL B CG1 1 
ATOM   3542 C CG2 . VAL B 1 217 ? -22.550 9.902   -29.746 1.00 13.47 ? 219 VAL B CG2 1 
ATOM   3543 N N   . LEU B 1 218 ? -21.701 7.014   -26.213 1.00 12.55 ? 220 LEU B N   1 
ATOM   3544 C CA  . LEU B 1 218 ? -21.105 6.031   -25.323 1.00 12.04 ? 220 LEU B CA  1 
ATOM   3545 C C   . LEU B 1 218 ? -21.735 4.676   -25.588 1.00 12.51 ? 220 LEU B C   1 
ATOM   3546 O O   . LEU B 1 218 ? -22.962 4.531   -25.569 1.00 11.99 ? 220 LEU B O   1 
ATOM   3547 C CB  . LEU B 1 218 ? -21.282 6.444   -23.841 1.00 13.09 ? 220 LEU B CB  1 
ATOM   3548 C CG  . LEU B 1 218 ? -20.981 5.442   -22.716 1.00 19.36 ? 220 LEU B CG  1 
ATOM   3549 C CD1 . LEU B 1 218 ? -19.487 5.222   -22.642 1.00 18.35 ? 220 LEU B CD1 1 
ATOM   3550 C CD2 . LEU B 1 218 ? -21.450 5.985   -21.380 1.00 20.97 ? 220 LEU B CD2 1 
ATOM   3551 N N   . LEU B 1 219 ? -20.888 3.683   -25.831 1.00 11.59 ? 221 LEU B N   1 
ATOM   3552 C CA  . LEU B 1 219 ? -21.299 2.293   -25.900 1.00 14.44 ? 221 LEU B CA  1 
ATOM   3553 C C   . LEU B 1 219 ? -20.580 1.564   -24.779 1.00 16.08 ? 221 LEU B C   1 
ATOM   3554 O O   . LEU B 1 219 ? -19.365 1.709   -24.626 1.00 12.90 ? 221 LEU B O   1 
ATOM   3555 C CB  . LEU B 1 219 ? -20.960 1.680   -27.262 1.00 17.30 ? 221 LEU B CB  1 
ATOM   3556 C CG  . LEU B 1 219 ? -21.053 0.159   -27.288 1.00 17.86 ? 221 LEU B CG  1 
ATOM   3557 C CD1 . LEU B 1 219 ? -22.512 -0.255  -27.255 1.00 18.70 ? 221 LEU B CD1 1 
ATOM   3558 C CD2 . LEU B 1 219 ? -20.401 -0.344  -28.562 1.00 18.41 ? 221 LEU B CD2 1 
ATOM   3559 N N   . GLU B 1 220 ? -21.329 0.826   -23.967 1.00 13.99 ? 222 GLU B N   1 
ATOM   3560 C CA  . GLU B 1 220 ? -20.758 0.252   -22.762 1.00 16.79 ? 222 GLU B CA  1 
ATOM   3561 C C   . GLU B 1 220 ? -21.321 -1.143  -22.539 1.00 18.60 ? 222 GLU B C   1 
ATOM   3562 O O   . GLU B 1 220 ? -22.495 -1.404  -22.835 1.00 17.57 ? 222 GLU B O   1 
ATOM   3563 C CB  . GLU B 1 220 ? -21.041 1.173   -21.569 1.00 18.56 ? 222 GLU B CB  1 
ATOM   3564 C CG  . GLU B 1 220 ? -20.386 0.791   -20.281 1.00 24.11 ? 222 GLU B CG  1 
ATOM   3565 C CD  . GLU B 1 220 ? -20.415 1.913   -19.252 1.00 20.84 ? 222 GLU B CD  1 
ATOM   3566 O OE1 . GLU B 1 220 ? -19.831 2.982   -19.509 1.00 26.40 ? 222 GLU B OE1 1 
ATOM   3567 O OE2 . GLU B 1 220 ? -21.031 1.722   -18.179 1.00 26.83 ? 222 GLU B OE2 1 
ATOM   3568 N N   . PHE B 1 221 ? -20.469 -2.047  -22.040 1.00 15.87 ? 223 PHE B N   1 
ATOM   3569 C CA  . PHE B 1 221 ? -20.890 -3.382  -21.638 1.00 16.66 ? 223 PHE B CA  1 
ATOM   3570 C C   . PHE B 1 221 ? -20.421 -3.615  -20.215 1.00 17.58 ? 223 PHE B C   1 
ATOM   3571 O O   . PHE B 1 221 ? -19.292 -3.259  -19.857 1.00 15.54 ? 223 PHE B O   1 
ATOM   3572 C CB  . PHE B 1 221 ? -20.336 -4.479  -22.568 1.00 16.76 ? 223 PHE B CB  1 
ATOM   3573 C CG  . PHE B 1 221 ? -20.937 -4.442  -23.926 1.00 17.38 ? 223 PHE B CG  1 
ATOM   3574 C CD1 . PHE B 1 221 ? -22.104 -5.143  -24.201 1.00 18.67 ? 223 PHE B CD1 1 
ATOM   3575 C CD2 . PHE B 1 221 ? -20.369 -3.670  -24.917 1.00 15.89 ? 223 PHE B CD2 1 
ATOM   3576 C CE1 . PHE B 1 221 ? -22.679 -5.083  -25.453 1.00 17.95 ? 223 PHE B CE1 1 
ATOM   3577 C CE2 . PHE B 1 221 ? -20.940 -3.596  -26.168 1.00 19.86 ? 223 PHE B CE2 1 
ATOM   3578 C CZ  . PHE B 1 221 ? -22.102 -4.287  -26.429 1.00 20.51 ? 223 PHE B CZ  1 
ATOM   3579 N N   . VAL B 1 222 ? -21.300 -4.176  -19.393 1.00 16.92 ? 224 VAL B N   1 
ATOM   3580 C CA  . VAL B 1 222 ? -20.948 -4.485  -18.013 1.00 16.74 ? 224 VAL B CA  1 
ATOM   3581 C C   . VAL B 1 222 ? -21.417 -5.893  -17.679 1.00 18.29 ? 224 VAL B C   1 
ATOM   3582 O O   . VAL B 1 222 ? -22.555 -6.265  -17.973 1.00 16.31 ? 224 VAL B O   1 
ATOM   3583 C CB  . VAL B 1 222 ? -21.529 -3.439  -17.043 1.00 22.53 ? 224 VAL B CB  1 
ATOM   3584 C CG1 . VAL B 1 222 ? -22.982 -3.246  -17.317 1.00 26.46 ? 224 VAL B CG1 1 
ATOM   3585 C CG2 . VAL B 1 222 ? -21.285 -3.861  -15.589 1.00 17.22 ? 224 VAL B CG2 1 
ATOM   3586 N N   . THR B 1 223 ? -20.529 -6.698  -17.100 1.00 14.67 ? 225 THR B N   1 
ATOM   3587 C CA  . THR B 1 223 ? -20.953 -8.030  -16.701 1.00 17.16 ? 225 THR B CA  1 
ATOM   3588 C C   . THR B 1 223 ? -20.329 -8.401  -15.365 1.00 16.02 ? 225 THR B C   1 
ATOM   3589 O O   . THR B 1 223 ? -19.234 -7.952  -15.003 1.00 14.27 ? 225 THR B O   1 
ATOM   3590 C CB  . THR B 1 223 ? -20.683 -9.066  -17.826 1.00 25.32 ? 225 THR B CB  1 
ATOM   3591 O OG1 . THR B 1 223 ? -20.112 -10.281 -17.316 1.00 25.42 ? 225 THR B OG1 1 
ATOM   3592 C CG2 . THR B 1 223 ? -19.885 -8.476  -18.950 1.00 13.78 ? 225 THR B CG2 1 
ATOM   3593 N N   . ALA B 1 224 ? -21.095 -9.154  -14.598 1.00 17.82 ? 226 ALA B N   1 
ATOM   3594 C CA  . ALA B 1 224 ? -20.730 -9.525  -13.241 1.00 18.44 ? 226 ALA B CA  1 
ATOM   3595 C C   . ALA B 1 224 ? -20.061 -10.891 -13.239 1.00 19.39 ? 226 ALA B C   1 
ATOM   3596 O O   . ALA B 1 224 ? -20.363 -11.745 -14.076 1.00 22.63 ? 226 ALA B O   1 
ATOM   3597 C CB  . ALA B 1 224 ? -21.967 -9.544  -12.338 1.00 20.01 ? 226 ALA B CB  1 
ATOM   3598 N N   . ALA B 1 225 ? -19.155 -11.090 -12.283 1.00 17.14 ? 227 ALA B N   1 
ATOM   3599 C CA  . ALA B 1 225 ? -18.444 -12.354 -12.141 1.00 24.65 ? 227 ALA B CA  1 
ATOM   3600 C C   . ALA B 1 225 ? -18.130 -12.583 -10.674 1.00 28.77 ? 227 ALA B C   1 
ATOM   3601 O O   . ALA B 1 225 ? -17.756 -11.644 -9.965  1.00 25.54 ? 227 ALA B O   1 
ATOM   3602 C CB  . ALA B 1 225 ? -17.151 -12.371 -12.953 1.00 24.13 ? 227 ALA B CB  1 
ATOM   3603 N N   . GLY B 1 226 ? -18.284 -13.834 -10.230 1.00 33.25 ? 228 GLY B N   1 
ATOM   3604 C CA  . GLY B 1 226 ? -18.083 -14.200 -8.841  1.00 32.97 ? 228 GLY B CA  1 
ATOM   3605 C C   . GLY B 1 226 ? -16.616 -14.341 -8.486  1.00 42.76 ? 228 GLY B C   1 
ATOM   3606 O O   . GLY B 1 226 ? -15.724 -13.950 -9.243  1.00 45.74 ? 228 GLY B O   1 
ATOM   3607 N N   . ILE B 1 227 ? -16.374 -14.955 -7.323  1.00 47.92 ? 229 ILE B N   1 
ATOM   3608 C CA  . ILE B 1 227 ? -15.063 -15.015 -6.647  1.00 49.44 ? 229 ILE B CA  1 
ATOM   3609 C C   . ILE B 1 227 ? -14.276 -13.720 -6.843  1.00 46.55 ? 229 ILE B C   1 
ATOM   3610 O O   . ILE B 1 227 ? -14.492 -12.740 -6.128  1.00 44.17 ? 229 ILE B O   1 
ATOM   3611 C CB  . ILE B 1 227 ? -14.205 -16.268 -7.082  1.00 47.07 ? 229 ILE B CB  1 
ATOM   3612 C CG1 . ILE B 1 227 ? -14.028 -16.410 -8.605  1.00 49.46 ? 229 ILE B CG1 1 
ATOM   3613 C CG2 . ILE B 1 227 ? -14.786 -17.548 -6.495  1.00 48.25 ? 229 ILE B CG2 1 
ATOM   3614 C CD1 . ILE B 1 227 ? -12.955 -15.507 -9.226  1.00 47.69 ? 229 ILE B CD1 1 
ATOM   3615 N N   . LYS C 1 3   ? -24.668 -31.995 -32.789 1.00 45.74 ? 3   LYS C N   1 
ATOM   3616 C CA  . LYS C 1 3   ? -24.335 -30.589 -32.618 1.00 44.09 ? 3   LYS C CA  1 
ATOM   3617 C C   . LYS C 1 3   ? -22.984 -30.412 -31.929 1.00 38.82 ? 3   LYS C C   1 
ATOM   3618 O O   . LYS C 1 3   ? -22.681 -31.052 -30.915 1.00 34.57 ? 3   LYS C O   1 
ATOM   3619 C CB  . LYS C 1 3   ? -25.424 -29.851 -31.818 1.00 40.12 ? 3   LYS C CB  1 
ATOM   3620 C CG  . LYS C 1 3   ? -26.777 -29.731 -32.521 1.00 46.83 ? 3   LYS C CG  1 
ATOM   3621 C CD  . LYS C 1 3   ? -26.628 -29.187 -33.943 1.00 47.10 ? 3   LYS C CD  1 
ATOM   3622 C CE  . LYS C 1 3   ? -27.481 -29.964 -34.971 1.00 55.52 ? 3   LYS C CE  1 
ATOM   3623 N NZ  . LYS C 1 3   ? -28.880 -30.301 -34.524 1.00 52.14 ? 3   LYS C NZ  1 
ATOM   3624 N N   . GLY C 1 4   ? -22.170 -29.534 -32.505 1.00 31.06 ? 4   GLY C N   1 
ATOM   3625 C CA  . GLY C 1 4   ? -21.033 -29.021 -31.770 1.00 26.44 ? 4   GLY C CA  1 
ATOM   3626 C C   . GLY C 1 4   ? -21.453 -28.234 -30.548 1.00 26.29 ? 4   GLY C C   1 
ATOM   3627 O O   . GLY C 1 4   ? -20.704 -28.161 -29.574 1.00 25.61 ? 4   GLY C O   1 
ATOM   3628 N N   . GLU C 1 5   ? -22.661 -27.646 -30.578 1.00 25.15 ? 5   GLU C N   1 
ATOM   3629 C CA  . GLU C 1 5   ? -23.163 -26.881 -29.437 1.00 27.63 ? 5   GLU C CA  1 
ATOM   3630 C C   . GLU C 1 5   ? -23.129 -27.697 -28.150 1.00 29.14 ? 5   GLU C C   1 
ATOM   3631 O O   . GLU C 1 5   ? -22.817 -27.166 -27.078 1.00 26.48 ? 5   GLU C O   1 
ATOM   3632 C CB  . GLU C 1 5   ? -24.592 -26.375 -29.707 1.00 28.10 ? 5   GLU C CB  1 
ATOM   3633 C CG  . GLU C 1 5   ? -24.732 -25.200 -30.689 1.00 36.71 ? 5   GLU C CG  1 
ATOM   3634 C CD  . GLU C 1 5   ? -24.317 -25.475 -32.140 1.00 37.26 ? 5   GLU C CD  1 
ATOM   3635 O OE1 . GLU C 1 5   ? -24.301 -26.648 -32.597 1.00 36.53 ? 5   GLU C OE1 1 
ATOM   3636 O OE2 . GLU C 1 5   ? -24.015 -24.470 -32.833 1.00 34.20 ? 5   GLU C OE2 1 
ATOM   3637 N N   . GLU C 1 6   ? -23.434 -28.995 -28.236 1.00 31.14 ? 6   GLU C N   1 
ATOM   3638 C CA  . GLU C 1 6   ? -23.476 -29.847 -27.049 1.00 28.34 ? 6   GLU C CA  1 
ATOM   3639 C C   . GLU C 1 6   ? -22.104 -30.014 -26.405 1.00 25.53 ? 6   GLU C C   1 
ATOM   3640 O O   . GLU C 1 6   ? -22.019 -30.317 -25.210 1.00 23.25 ? 6   GLU C O   1 
ATOM   3641 C CB  . GLU C 1 6   ? -24.061 -31.215 -27.426 1.00 33.65 ? 6   GLU C CB  1 
ATOM   3642 C CG  . GLU C 1 6   ? -25.412 -31.109 -28.154 1.00 39.04 ? 6   GLU C CG  1 
ATOM   3643 C CD  . GLU C 1 6   ? -26.128 -32.448 -28.310 1.00 50.65 ? 6   GLU C CD  1 
ATOM   3644 O OE1 . GLU C 1 6   ? -27.378 -32.449 -28.372 1.00 51.58 ? 6   GLU C OE1 1 
ATOM   3645 O OE2 . GLU C 1 6   ? -25.445 -33.497 -28.368 1.00 53.54 ? 6   GLU C OE2 1 
ATOM   3646 N N   . LEU C 1 7   ? -21.029 -29.818 -27.170 1.00 25.25 ? 7   LEU C N   1 
ATOM   3647 C CA  . LEU C 1 7   ? -19.676 -29.939 -26.648 1.00 23.22 ? 7   LEU C CA  1 
ATOM   3648 C C   . LEU C 1 7   ? -19.310 -28.793 -25.719 1.00 23.41 ? 7   LEU C C   1 
ATOM   3649 O O   . LEU C 1 7   ? -18.268 -28.864 -25.056 1.00 21.68 ? 7   LEU C O   1 
ATOM   3650 C CB  . LEU C 1 7   ? -18.691 -29.985 -27.814 1.00 21.71 ? 7   LEU C CB  1 
ATOM   3651 C CG  . LEU C 1 7   ? -18.834 -31.226 -28.692 1.00 22.02 ? 7   LEU C CG  1 
ATOM   3652 C CD1 . LEU C 1 7   ? -17.851 -31.176 -29.868 1.00 19.96 ? 7   LEU C CD1 1 
ATOM   3653 C CD2 . LEU C 1 7   ? -18.607 -32.464 -27.854 1.00 25.65 ? 7   LEU C CD2 1 
ATOM   3654 N N   . PHE C 1 8   ? -20.149 -27.757 -25.636 1.00 21.07 ? 8   PHE C N   1 
ATOM   3655 C CA  . PHE C 1 8   ? -19.834 -26.571 -24.853 1.00 23.32 ? 8   PHE C CA  1 
ATOM   3656 C C   . PHE C 1 8   ? -20.764 -26.376 -23.655 1.00 24.97 ? 8   PHE C C   1 
ATOM   3657 O O   . PHE C 1 8   ? -20.792 -25.284 -23.082 1.00 25.50 ? 8   PHE C O   1 
ATOM   3658 C CB  . PHE C 1 8   ? -19.870 -25.327 -25.750 1.00 20.26 ? 8   PHE C CB  1 
ATOM   3659 C CG  . PHE C 1 8   ? -18.778 -25.290 -26.773 1.00 18.20 ? 8   PHE C CG  1 
ATOM   3660 C CD1 . PHE C 1 8   ? -18.926 -25.924 -27.995 1.00 15.83 ? 8   PHE C CD1 1 
ATOM   3661 C CD2 . PHE C 1 8   ? -17.574 -24.675 -26.489 1.00 16.52 ? 8   PHE C CD2 1 
ATOM   3662 C CE1 . PHE C 1 8   ? -17.911 -25.901 -28.943 1.00 17.07 ? 8   PHE C CE1 1 
ATOM   3663 C CE2 . PHE C 1 8   ? -16.546 -24.659 -27.425 1.00 15.71 ? 8   PHE C CE2 1 
ATOM   3664 C CZ  . PHE C 1 8   ? -16.715 -25.266 -28.654 1.00 15.26 ? 8   PHE C CZ  1 
ATOM   3665 N N   . THR C 1 9   ? -21.509 -27.412 -23.239 1.00 27.54 ? 9   THR C N   1 
ATOM   3666 C CA  . THR C 1 9   ? -22.517 -27.208 -22.192 1.00 29.41 ? 9   THR C CA  1 
ATOM   3667 C C   . THR C 1 9   ? -21.908 -27.020 -20.808 1.00 30.79 ? 9   THR C C   1 
ATOM   3668 O O   . THR C 1 9   ? -22.597 -26.520 -19.907 1.00 30.51 ? 9   THR C O   1 
ATOM   3669 C CB  . THR C 1 9   ? -23.511 -28.373 -22.137 1.00 31.88 ? 9   THR C CB  1 
ATOM   3670 O OG1 . THR C 1 9   ? -22.835 -29.604 -22.399 1.00 29.00 ? 9   THR C OG1 1 
ATOM   3671 C CG2 . THR C 1 9   ? -24.575 -28.184 -23.195 1.00 29.85 ? 9   THR C CG2 1 
ATOM   3672 N N   . GLY C 1 10  ? -20.653 -27.416 -20.605 1.00 26.46 ? 10  GLY C N   1 
ATOM   3673 C CA  . GLY C 1 10  ? -20.007 -27.157 -19.331 1.00 28.57 ? 10  GLY C CA  1 
ATOM   3674 C C   . GLY C 1 10  ? -18.709 -26.384 -19.460 1.00 28.15 ? 10  GLY C C   1 
ATOM   3675 O O   . GLY C 1 10  ? -18.507 -25.662 -20.443 1.00 25.77 ? 10  GLY C O   1 
ATOM   3676 N N   . VAL C 1 11  ? -17.822 -26.521 -18.479 1.00 24.45 ? 11  VAL C N   1 
ATOM   3677 C CA  . VAL C 1 11  ? -16.517 -25.869 -18.533 1.00 24.04 ? 11  VAL C CA  1 
ATOM   3678 C C   . VAL C 1 11  ? -15.597 -26.716 -19.404 1.00 24.74 ? 11  VAL C C   1 
ATOM   3679 O O   . VAL C 1 11  ? -15.455 -27.925 -19.182 1.00 23.03 ? 11  VAL C O   1 
ATOM   3680 C CB  . VAL C 1 11  ? -15.944 -25.690 -17.117 1.00 22.91 ? 11  VAL C CB  1 
ATOM   3681 C CG1 . VAL C 1 11  ? -14.504 -25.199 -17.165 1.00 22.56 ? 11  VAL C CG1 1 
ATOM   3682 C CG2 . VAL C 1 11  ? -16.832 -24.752 -16.307 1.00 23.70 ? 11  VAL C CG2 1 
ATOM   3683 N N   . VAL C 1 12  ? -14.991 -26.093 -20.407 1.00 18.14 ? 12  VAL C N   1 
ATOM   3684 C CA  . VAL C 1 12  ? -14.194 -26.774 -21.424 1.00 18.84 ? 12  VAL C CA  1 
ATOM   3685 C C   . VAL C 1 12  ? -12.746 -26.326 -21.264 1.00 16.61 ? 12  VAL C C   1 
ATOM   3686 O O   . VAL C 1 12  ? -12.474 -25.123 -21.326 1.00 16.24 ? 12  VAL C O   1 
ATOM   3687 C CB  . VAL C 1 12  ? -14.698 -26.455 -22.844 1.00 16.92 ? 12  VAL C CB  1 
ATOM   3688 C CG1 . VAL C 1 12  ? -13.767 -27.073 -23.903 1.00 13.84 ? 12  VAL C CG1 1 
ATOM   3689 C CG2 . VAL C 1 12  ? -16.150 -26.887 -23.025 1.00 17.69 ? 12  VAL C CG2 1 
ATOM   3690 N N   . PRO C 1 13  ? -11.787 -27.234 -21.087 1.00 16.95 ? 13  PRO C N   1 
ATOM   3691 C CA  . PRO C 1 13  ? -10.388 -26.791 -20.989 1.00 17.22 ? 13  PRO C CA  1 
ATOM   3692 C C   . PRO C 1 13  ? -9.931  -26.225 -22.326 1.00 13.07 ? 13  PRO C C   1 
ATOM   3693 O O   . PRO C 1 13  ? -10.314 -26.722 -23.389 1.00 12.71 ? 13  PRO C O   1 
ATOM   3694 C CB  . PRO C 1 13  ? -9.615  -28.067 -20.638 1.00 19.40 ? 13  PRO C CB  1 
ATOM   3695 C CG  . PRO C 1 13  ? -10.598 -29.168 -20.552 1.00 21.27 ? 13  PRO C CG  1 
ATOM   3696 C CD  . PRO C 1 13  ? -11.973 -28.660 -20.781 1.00 19.68 ? 13  PRO C CD  1 
ATOM   3697 N N   . ILE C 1 14  ? -9.100  -25.185 -22.273 1.00 13.81 ? 14  ILE C N   1 
ATOM   3698 C CA  . ILE C 1 14  ? -8.583  -24.534 -23.473 1.00 13.26 ? 14  ILE C CA  1 
ATOM   3699 C C   . ILE C 1 14  ? -7.069  -24.637 -23.507 1.00 13.49 ? 14  ILE C C   1 
ATOM   3700 O O   . ILE C 1 14  ? -6.396  -24.387 -22.499 1.00 13.35 ? 14  ILE C O   1 
ATOM   3701 C CB  . ILE C 1 14  ? -9.002  -23.049 -23.544 1.00 12.36 ? 14  ILE C CB  1 
ATOM   3702 C CG1 . ILE C 1 14  ? -10.524 -22.929 -23.613 1.00 13.99 ? 14  ILE C CG1 1 
ATOM   3703 C CG2 . ILE C 1 14  ? -8.301  -22.342 -24.728 1.00 12.42 ? 14  ILE C CG2 1 
ATOM   3704 C CD1 . ILE C 1 14  ? -11.015 -21.486 -23.511 1.00 12.33 ? 14  ILE C CD1 1 
ATOM   3705 N N   . LEU C 1 15  ? -6.540  -24.948 -24.685 1.00 12.00 ? 15  LEU C N   1 
ATOM   3706 C CA  . LEU C 1 15  ? -5.116  -24.872 -24.974 1.00 11.40 ? 15  LEU C CA  1 
ATOM   3707 C C   . LEU C 1 15  ? -4.922  -23.940 -26.166 1.00 13.62 ? 15  LEU C C   1 
ATOM   3708 O O   . LEU C 1 15  ? -5.661  -24.029 -27.156 1.00 12.87 ? 15  LEU C O   1 
ATOM   3709 C CB  . LEU C 1 15  ? -4.534  -26.260 -25.300 1.00 12.91 ? 15  LEU C CB  1 
ATOM   3710 C CG  . LEU C 1 15  ? -3.111  -26.276 -25.863 1.00 12.68 ? 15  LEU C CG  1 
ATOM   3711 C CD1 . LEU C 1 15  ? -2.112  -25.889 -24.762 1.00 15.44 ? 15  LEU C CD1 1 
ATOM   3712 C CD2 . LEU C 1 15  ? -2.782  -27.649 -26.445 1.00 14.18 ? 15  LEU C CD2 1 
ATOM   3713 N N   . VAL C 1 16  ? -3.955  -23.030 -26.054 1.00 10.64 ? 16  VAL C N   1 
ATOM   3714 C CA  . VAL C 1 16  ? -3.543  -22.158 -27.152 1.00 13.08 ? 16  VAL C CA  1 
ATOM   3715 C C   . VAL C 1 16  ? -2.056  -22.363 -27.415 1.00 13.78 ? 16  VAL C C   1 
ATOM   3716 O O   . VAL C 1 16  ? -1.247  -22.328 -26.480 1.00 12.21 ? 16  VAL C O   1 
ATOM   3717 C CB  . VAL C 1 16  ? -3.835  -20.675 -26.853 1.00 14.20 ? 16  VAL C CB  1 
ATOM   3718 C CG1 . VAL C 1 16  ? -3.483  -19.850 -28.074 1.00 12.20 ? 16  VAL C CG1 1 
ATOM   3719 C CG2 . VAL C 1 16  ? -5.328  -20.473 -26.509 1.00 11.95 ? 16  VAL C CG2 1 
ATOM   3720 N N   . GLU C 1 17  ? -1.695  -22.553 -28.682 1.00 10.45 ? 17  GLU C N   1 
ATOM   3721 C CA  . GLU C 1 17  ? -0.298  -22.708 -29.074 1.00 12.90 ? 17  GLU C CA  1 
ATOM   3722 C C   . GLU C 1 17  ? -0.032  -21.816 -30.282 1.00 14.35 ? 17  GLU C C   1 
ATOM   3723 O O   . GLU C 1 17  ? -0.659  -21.993 -31.332 1.00 15.10 ? 17  GLU C O   1 
ATOM   3724 C CB  . GLU C 1 17  ? 0.012   -24.177 -29.413 1.00 15.57 ? 17  GLU C CB  1 
ATOM   3725 C CG  . GLU C 1 17  ? -0.033  -25.144 -28.214 1.00 13.24 ? 17  GLU C CG  1 
ATOM   3726 C CD  . GLU C 1 17  ? 1.025   -24.873 -27.140 1.00 18.09 ? 17  GLU C CD  1 
ATOM   3727 O OE1 . GLU C 1 17  ? 1.875   -23.980 -27.333 1.00 19.56 ? 17  GLU C OE1 1 
ATOM   3728 O OE2 . GLU C 1 17  ? 1.021   -25.578 -26.100 1.00 18.84 ? 17  GLU C OE2 1 
ATOM   3729 N N   . LEU C 1 18  ? 0.918   -20.892 -30.158 1.00 12.51 ? 18  LEU C N   1 
ATOM   3730 C CA  . LEU C 1 18  ? 1.224   -19.945 -31.228 1.00 13.60 ? 18  LEU C CA  1 
ATOM   3731 C C   . LEU C 1 18  ? 2.696   -20.032 -31.596 1.00 13.91 ? 18  LEU C C   1 
ATOM   3732 O O   . LEU C 1 18  ? 3.562   -19.996 -30.716 1.00 14.86 ? 18  LEU C O   1 
ATOM   3733 C CB  . LEU C 1 18  ? 0.902   -18.506 -30.811 1.00 10.42 ? 18  LEU C CB  1 
ATOM   3734 C CG  . LEU C 1 18  ? 1.193   -17.465 -31.891 1.00 15.20 ? 18  LEU C CG  1 
ATOM   3735 C CD1 . LEU C 1 18  ? 0.048   -16.484 -31.983 1.00 17.50 ? 18  LEU C CD1 1 
ATOM   3736 C CD2 . LEU C 1 18  ? 2.541   -16.767 -31.733 1.00 16.54 ? 18  LEU C CD2 1 
ATOM   3737 N N   . ASP C 1 19  ? 2.973   -20.155 -32.887 1.00 13.44 ? 19  ASP C N   1 
ATOM   3738 C CA  . ASP C 1 19  ? 4.327   -20.056 -33.425 1.00 14.54 ? 19  ASP C CA  1 
ATOM   3739 C C   . ASP C 1 19  ? 4.409   -18.769 -34.234 1.00 13.87 ? 19  ASP C C   1 
ATOM   3740 O O   . ASP C 1 19  ? 3.621   -18.570 -35.162 1.00 16.26 ? 19  ASP C O   1 
ATOM   3741 C CB  . ASP C 1 19  ? 4.660   -21.283 -34.274 1.00 18.37 ? 19  ASP C CB  1 
ATOM   3742 C CG  . ASP C 1 19  ? 5.987   -21.160 -35.004 1.00 23.56 ? 19  ASP C CG  1 
ATOM   3743 O OD1 . ASP C 1 19  ? 7.007   -20.846 -34.366 1.00 28.64 ? 19  ASP C OD1 1 
ATOM   3744 O OD2 . ASP C 1 19  ? 6.010   -21.472 -36.208 1.00 31.15 ? 19  ASP C OD2 1 
ATOM   3745 N N   . GLY C 1 20  ? 5.363   -17.915 -33.893 1.00 15.78 ? 20  GLY C N   1 
ATOM   3746 C CA  . GLY C 1 20  ? 5.417   -16.579 -34.449 1.00 14.12 ? 20  GLY C CA  1 
ATOM   3747 C C   . GLY C 1 20  ? 6.779   -16.210 -34.995 1.00 16.64 ? 20  GLY C C   1 
ATOM   3748 O O   . GLY C 1 20  ? 7.819   -16.674 -34.529 1.00 16.14 ? 20  GLY C O   1 
ATOM   3749 N N   . ASP C 1 21  ? 6.752   -15.344 -35.998 1.00 15.17 ? 21  ASP C N   1 
ATOM   3750 C CA  . ASP C 1 21  ? 7.967   -14.781 -36.576 1.00 15.90 ? 21  ASP C CA  1 
ATOM   3751 C C   . ASP C 1 21  ? 7.607   -13.366 -37.007 1.00 16.77 ? 21  ASP C C   1 
ATOM   3752 O O   . ASP C 1 21  ? 6.815   -13.198 -37.938 1.00 16.64 ? 21  ASP C O   1 
ATOM   3753 C CB  . ASP C 1 21  ? 8.438   -15.616 -37.756 1.00 16.88 ? 21  ASP C CB  1 
ATOM   3754 C CG  . ASP C 1 21  ? 9.722   -15.096 -38.374 1.00 23.21 ? 21  ASP C CG  1 
ATOM   3755 O OD1 . ASP C 1 21  ? 10.062  -13.926 -38.156 1.00 23.14 ? 21  ASP C OD1 1 
ATOM   3756 O OD2 . ASP C 1 21  ? 10.358  -15.846 -39.138 1.00 24.37 ? 21  ASP C OD2 1 
ATOM   3757 N N   . VAL C 1 22  ? 8.164   -12.363 -36.333 1.00 15.06 ? 22  VAL C N   1 
ATOM   3758 C CA  . VAL C 1 22  ? 7.912   -10.960 -36.655 1.00 16.31 ? 22  VAL C CA  1 
ATOM   3759 C C   . VAL C 1 22  ? 9.249   -10.335 -37.021 1.00 16.75 ? 22  VAL C C   1 
ATOM   3760 O O   . VAL C 1 22  ? 10.117  -10.165 -36.155 1.00 15.99 ? 22  VAL C O   1 
ATOM   3761 C CB  . VAL C 1 22  ? 7.248   -10.209 -35.495 1.00 15.72 ? 22  VAL C CB  1 
ATOM   3762 C CG1 . VAL C 1 22  ? 7.050   -8.722  -35.847 1.00 18.10 ? 22  VAL C CG1 1 
ATOM   3763 C CG2 . VAL C 1 22  ? 5.907   -10.844 -35.137 1.00 12.53 ? 22  VAL C CG2 1 
ATOM   3764 N N   . ASN C 1 23  ? 9.412   -9.983  -38.299 1.00 20.09 ? 23  ASN C N   1 
ATOM   3765 C CA  . ASN C 1 23  ? 10.653  -9.378  -38.801 1.00 21.97 ? 23  ASN C CA  1 
ATOM   3766 C C   . ASN C 1 23  ? 11.865  -10.258 -38.509 1.00 23.11 ? 23  ASN C C   1 
ATOM   3767 O O   . ASN C 1 23  ? 12.957  -9.748  -38.255 1.00 21.47 ? 23  ASN C O   1 
ATOM   3768 C CB  . ASN C 1 23  ? 10.901  -7.984  -38.212 1.00 19.11 ? 23  ASN C CB  1 
ATOM   3769 C CG  . ASN C 1 23  ? 10.213  -6.885  -38.997 1.00 20.49 ? 23  ASN C CG  1 
ATOM   3770 O OD1 . ASN C 1 23  ? 9.165   -7.108  -39.604 1.00 18.88 ? 23  ASN C OD1 1 
ATOM   3771 N ND2 . ASN C 1 23  ? 10.823  -5.699  -39.022 1.00 22.81 ? 23  ASN C ND2 1 
ATOM   3772 N N   . GLY C 1 24  ? 11.685  -11.578 -38.504 1.00 19.20 ? 24  GLY C N   1 
ATOM   3773 C CA  . GLY C 1 24  ? 12.775  -12.475 -38.185 1.00 23.46 ? 24  GLY C CA  1 
ATOM   3774 C C   . GLY C 1 24  ? 12.949  -12.766 -36.710 1.00 23.63 ? 24  GLY C C   1 
ATOM   3775 O O   . GLY C 1 24  ? 13.776  -13.616 -36.355 1.00 23.67 ? 24  GLY C O   1 
ATOM   3776 N N   . HIS C 1 25  ? 12.206  -12.088 -35.840 1.00 17.60 ? 25  HIS C N   1 
ATOM   3777 C CA  . HIS C 1 25  ? 12.237  -12.356 -34.405 1.00 18.65 ? 25  HIS C CA  1 
ATOM   3778 C C   . HIS C 1 25  ? 11.252  -13.487 -34.130 1.00 19.38 ? 25  HIS C C   1 
ATOM   3779 O O   . HIS C 1 25  ? 10.039  -13.276 -34.166 1.00 17.99 ? 25  HIS C O   1 
ATOM   3780 C CB  . HIS C 1 25  ? 11.852  -11.108 -33.622 1.00 21.25 ? 25  HIS C CB  1 
ATOM   3781 C CG  . HIS C 1 25  ? 12.731  -9.921  -33.885 1.00 26.37 ? 25  HIS C CG  1 
ATOM   3782 N ND1 . HIS C 1 25  ? 13.997  -9.791  -33.355 1.00 29.31 ? 25  HIS C ND1 1 
ATOM   3783 C CD2 . HIS C 1 25  ? 12.529  -8.821  -34.650 1.00 25.16 ? 25  HIS C CD2 1 
ATOM   3784 C CE1 . HIS C 1 25  ? 14.526  -8.648  -33.758 1.00 28.79 ? 25  HIS C CE1 1 
ATOM   3785 N NE2 . HIS C 1 25  ? 13.655  -8.038  -34.542 1.00 24.19 ? 25  HIS C NE2 1 
ATOM   3786 N N   . LYS C 1 26  ? 11.759  -14.687 -33.884 1.00 19.18 ? 26  LYS C N   1 
ATOM   3787 C CA  . LYS C 1 26  ? 10.896  -15.850 -33.754 1.00 19.24 ? 26  LYS C CA  1 
ATOM   3788 C C   . LYS C 1 26  ? 10.585  -16.109 -32.288 1.00 18.65 ? 26  LYS C C   1 
ATOM   3789 O O   . LYS C 1 26  ? 11.403  -15.839 -31.407 1.00 19.10 ? 26  LYS C O   1 
ATOM   3790 C CB  . LYS C 1 26  ? 11.544  -17.077 -34.387 1.00 19.32 ? 26  LYS C CB  1 
ATOM   3791 C CG  . LYS C 1 26  ? 11.834  -16.905 -35.866 1.00 21.64 ? 26  LYS C CG  1 
ATOM   3792 C CD  . LYS C 1 26  ? 12.752  -17.996 -36.376 1.00 23.33 ? 26  LYS C CD  1 
ATOM   3793 C CE  . LYS C 1 26  ? 13.046  -17.819 -37.856 1.00 28.06 ? 26  LYS C CE  1 
ATOM   3794 N NZ  . LYS C 1 26  ? 11.941  -18.275 -38.736 1.00 34.40 ? 26  LYS C NZ  1 
ATOM   3795 N N   . PHE C 1 27  ? 9.388   -16.630 -32.031 1.00 17.47 ? 27  PHE C N   1 
ATOM   3796 C CA  . PHE C 1 27  ? 8.937   -16.817 -30.659 1.00 13.51 ? 27  PHE C CA  1 
ATOM   3797 C C   . PHE C 1 27  ? 7.771   -17.793 -30.627 1.00 16.77 ? 27  PHE C C   1 
ATOM   3798 O O   . PHE C 1 27  ? 7.127   -18.069 -31.645 1.00 15.03 ? 27  PHE C O   1 
ATOM   3799 C CB  . PHE C 1 27  ? 8.534   -15.485 -30.010 1.00 14.92 ? 27  PHE C CB  1 
ATOM   3800 C CG  . PHE C 1 27  ? 7.360   -14.812 -30.677 1.00 16.10 ? 27  PHE C CG  1 
ATOM   3801 C CD1 . PHE C 1 27  ? 7.545   -14.020 -31.802 1.00 18.13 ? 27  PHE C CD1 1 
ATOM   3802 C CD2 . PHE C 1 27  ? 6.080   -14.940 -30.160 1.00 13.44 ? 27  PHE C CD2 1 
ATOM   3803 C CE1 . PHE C 1 27  ? 6.460   -13.394 -32.415 1.00 14.59 ? 27  PHE C CE1 1 
ATOM   3804 C CE2 . PHE C 1 27  ? 5.004   -14.312 -30.761 1.00 16.49 ? 27  PHE C CE2 1 
ATOM   3805 C CZ  . PHE C 1 27  ? 5.191   -13.546 -31.885 1.00 15.04 ? 27  PHE C CZ  1 
ATOM   3806 N N   . SER C 1 28  ? 7.511   -18.317 -29.440 1.00 12.80 ? 28  SER C N   1 
ATOM   3807 C CA  . SER C 1 28  ? 6.376   -19.199 -29.222 1.00 12.95 ? 28  SER C CA  1 
ATOM   3808 C C   . SER C 1 28  ? 5.599   -18.709 -28.009 1.00 15.35 ? 28  SER C C   1 
ATOM   3809 O O   . SER C 1 28  ? 6.170   -18.174 -27.054 1.00 16.88 ? 28  SER C O   1 
ATOM   3810 C CB  . SER C 1 28  ? 6.840   -20.664 -29.031 1.00 15.94 ? 28  SER C CB  1 
ATOM   3811 O OG  . SER C 1 28  ? 5.740   -21.539 -28.862 1.00 19.75 ? 28  SER C OG  1 
ATOM   3812 N N   . VAL C 1 29  ? 4.287   -18.875 -28.058 1.00 11.42 ? 29  VAL C N   1 
ATOM   3813 C CA  . VAL C 1 29  ? 3.428   -18.547 -26.938 1.00 11.84 ? 29  VAL C CA  1 
ATOM   3814 C C   . VAL C 1 29  ? 2.548   -19.754 -26.663 1.00 12.22 ? 29  VAL C C   1 
ATOM   3815 O O   . VAL C 1 29  ? 2.039   -20.381 -27.595 1.00 12.76 ? 29  VAL C O   1 
ATOM   3816 C CB  . VAL C 1 29  ? 2.568   -17.291 -27.219 1.00 12.67 ? 29  VAL C CB  1 
ATOM   3817 C CG1 . VAL C 1 29  ? 1.496   -17.140 -26.131 1.00 11.25 ? 29  VAL C CG1 1 
ATOM   3818 C CG2 . VAL C 1 29  ? 3.446   -16.037 -27.294 1.00 11.68 ? 29  VAL C CG2 1 
ATOM   3819 N N   . SER C 1 30  ? 2.388   -20.096 -25.387 1.00 12.87 ? 30  SER C N   1 
ATOM   3820 C CA  . SER C 1 30  ? 1.489   -21.161 -24.963 1.00 11.04 ? 30  SER C CA  1 
ATOM   3821 C C   . SER C 1 30  ? 0.459   -20.584 -24.005 1.00 16.09 ? 30  SER C C   1 
ATOM   3822 O O   . SER C 1 30  ? 0.801   -19.785 -23.130 1.00 15.48 ? 30  SER C O   1 
ATOM   3823 C CB  . SER C 1 30  ? 2.251   -22.301 -24.254 1.00 18.07 ? 30  SER C CB  1 
ATOM   3824 O OG  . SER C 1 30  ? 3.019   -23.047 -25.188 1.00 21.99 ? 30  SER C OG  1 
ATOM   3825 N N   . GLY C 1 31  ? -0.783  -20.999 -24.150 1.00 14.89 ? 31  GLY C N   1 
ATOM   3826 C CA  . GLY C 1 31  ? -1.846  -20.535 -23.271 1.00 12.90 ? 31  GLY C CA  1 
ATOM   3827 C C   . GLY C 1 31  ? -2.646  -21.700 -22.737 1.00 15.65 ? 31  GLY C C   1 
ATOM   3828 O O   . GLY C 1 31  ? -2.863  -22.695 -23.434 1.00 13.40 ? 31  GLY C O   1 
ATOM   3829 N N   . GLU C 1 32  ? -3.055  -21.584 -21.477 1.00 15.69 ? 32  GLU C N   1 
ATOM   3830 C CA  . GLU C 1 32  ? -3.882  -22.599 -20.847 1.00 16.29 ? 32  GLU C CA  1 
ATOM   3831 C C   . GLU C 1 32  ? -4.942  -21.939 -19.980 1.00 14.04 ? 32  GLU C C   1 
ATOM   3832 O O   . GLU C 1 32  ? -4.691  -20.929 -19.323 1.00 14.96 ? 32  GLU C O   1 
ATOM   3833 C CB  . GLU C 1 32  ? -3.054  -23.590 -20.000 1.00 20.34 ? 32  GLU C CB  1 
ATOM   3834 C CG  . GLU C 1 32  ? -1.864  -24.215 -20.712 1.00 28.70 ? 32  GLU C CG  1 
ATOM   3835 C CD  . GLU C 1 32  ? -1.247  -25.346 -19.896 1.00 36.61 ? 32  GLU C CD  1 
ATOM   3836 O OE1 . GLU C 1 32  ? -0.744  -25.059 -18.788 1.00 42.29 ? 32  GLU C OE1 1 
ATOM   3837 O OE2 . GLU C 1 32  ? -1.293  -26.515 -20.343 1.00 35.58 ? 32  GLU C OE2 1 
ATOM   3838 N N   . GLY C 1 33  ? -6.130  -22.532 -19.985 1.00 15.28 ? 33  GLY C N   1 
ATOM   3839 C CA  . GLY C 1 33  ? -7.205  -22.063 -19.126 1.00 17.03 ? 33  GLY C CA  1 
ATOM   3840 C C   . GLY C 1 33  ? -8.481  -22.822 -19.400 1.00 15.60 ? 33  GLY C C   1 
ATOM   3841 O O   . GLY C 1 33  ? -8.453  -24.014 -19.727 1.00 16.59 ? 33  GLY C O   1 
ATOM   3842 N N   . GLU C 1 34  ? -9.606  -22.123 -19.273 1.00 16.31 ? 34  GLU C N   1 
ATOM   3843 C CA  . GLU C 1 34  ? -10.876 -22.802 -19.497 1.00 18.97 ? 34  GLU C CA  1 
ATOM   3844 C C   . GLU C 1 34  ? -11.917 -21.813 -19.989 1.00 16.22 ? 34  GLU C C   1 
ATOM   3845 O O   . GLU C 1 34  ? -11.813 -20.603 -19.774 1.00 18.18 ? 34  GLU C O   1 
ATOM   3846 C CB  . GLU C 1 34  ? -11.416 -23.480 -18.232 1.00 21.97 ? 34  GLU C CB  1 
ATOM   3847 C CG  . GLU C 1 34  ? -11.130 -22.747 -16.969 1.00 28.42 ? 34  GLU C CG  1 
ATOM   3848 C CD  . GLU C 1 34  ? -11.547 -23.534 -15.741 1.00 33.55 ? 34  GLU C CD  1 
ATOM   3849 O OE1 . GLU C 1 34  ? -11.418 -24.782 -15.745 1.00 36.40 ? 34  GLU C OE1 1 
ATOM   3850 O OE2 . GLU C 1 34  ? -12.033 -22.898 -14.784 1.00 40.04 ? 34  GLU C OE2 1 
ATOM   3851 N N   . GLY C 1 35  ? -12.953 -22.354 -20.611 1.00 13.87 ? 35  GLY C N   1 
ATOM   3852 C CA  . GLY C 1 35  ? -14.030 -21.536 -21.125 1.00 15.16 ? 35  GLY C CA  1 
ATOM   3853 C C   . GLY C 1 35  ? -15.386 -22.079 -20.732 1.00 17.89 ? 35  GLY C C   1 
ATOM   3854 O O   . GLY C 1 35  ? -15.601 -23.289 -20.631 1.00 16.34 ? 35  GLY C O   1 
ATOM   3855 N N   . ASP C 1 36  ? -16.310 -21.150 -20.514 1.00 16.79 ? 36  ASP C N   1 
ATOM   3856 C CA  . ASP C 1 36  ? -17.689 -21.458 -20.161 1.00 17.60 ? 36  ASP C CA  1 
ATOM   3857 C C   . ASP C 1 36  ? -18.554 -20.724 -21.177 1.00 19.19 ? 36  ASP C C   1 
ATOM   3858 O O   . ASP C 1 36  ? -18.863 -19.542 -20.989 1.00 18.33 ? 36  ASP C O   1 
ATOM   3859 C CB  . ASP C 1 36  ? -18.005 -21.005 -18.746 1.00 17.41 ? 36  ASP C CB  1 
ATOM   3860 C CG  . ASP C 1 36  ? -19.415 -21.371 -18.322 1.00 23.25 ? 36  ASP C CG  1 
ATOM   3861 O OD1 . ASP C 1 36  ? -20.235 -21.732 -19.195 1.00 23.66 ? 36  ASP C OD1 1 
ATOM   3862 O OD2 . ASP C 1 36  ? -19.730 -21.222 -17.126 1.00 29.47 ? 36  ASP C OD2 1 
ATOM   3863 N N   . ALA C 1 37  ? -18.956 -21.427 -22.238 1.00 14.29 ? 37  ALA C N   1 
ATOM   3864 C CA  . ALA C 1 37  ? -19.773 -20.798 -23.272 1.00 18.84 ? 37  ALA C CA  1 
ATOM   3865 C C   . ALA C 1 37  ? -21.194 -20.500 -22.803 1.00 21.12 ? 37  ALA C C   1 
ATOM   3866 O O   . ALA C 1 37  ? -21.883 -19.686 -23.430 1.00 19.05 ? 37  ALA C O   1 
ATOM   3867 C CB  . ALA C 1 37  ? -19.822 -21.677 -24.517 1.00 18.55 ? 37  ALA C CB  1 
ATOM   3868 N N   . THR C 1 38  ? -21.654 -21.143 -21.729 1.00 20.56 ? 38  THR C N   1 
ATOM   3869 C CA  . THR C 1 38  ? -22.991 -20.850 -21.228 1.00 22.26 ? 38  THR C CA  1 
ATOM   3870 C C   . THR C 1 38  ? -23.085 -19.413 -20.713 1.00 23.48 ? 38  THR C C   1 
ATOM   3871 O O   . THR C 1 38  ? -24.092 -18.732 -20.938 1.00 27.21 ? 38  THR C O   1 
ATOM   3872 C CB  . THR C 1 38  ? -23.372 -21.854 -20.140 1.00 24.07 ? 38  THR C CB  1 
ATOM   3873 O OG1 . THR C 1 38  ? -23.372 -23.180 -20.698 1.00 25.32 ? 38  THR C OG1 1 
ATOM   3874 C CG2 . THR C 1 38  ? -24.774 -21.561 -19.615 1.00 29.97 ? 38  THR C CG2 1 
ATOM   3875 N N   . TYR C 1 39  ? -22.048 -18.926 -20.034 1.00 20.74 ? 39  TYR C N   1 
ATOM   3876 C CA  . TYR C 1 39  ? -22.014 -17.524 -19.629 1.00 21.48 ? 39  TYR C CA  1 
ATOM   3877 C C   . TYR C 1 39  ? -21.178 -16.666 -20.559 1.00 20.26 ? 39  TYR C C   1 
ATOM   3878 O O   . TYR C 1 39  ? -21.306 -15.434 -20.520 1.00 23.37 ? 39  TYR C O   1 
ATOM   3879 C CB  . TYR C 1 39  ? -21.453 -17.369 -18.215 1.00 21.08 ? 39  TYR C CB  1 
ATOM   3880 C CG  . TYR C 1 39  ? -21.725 -16.011 -17.582 1.00 25.34 ? 39  TYR C CG  1 
ATOM   3881 C CD1 . TYR C 1 39  ? -23.014 -15.484 -17.540 1.00 25.18 ? 39  TYR C CD1 1 
ATOM   3882 C CD2 . TYR C 1 39  ? -20.693 -15.258 -17.028 1.00 23.50 ? 39  TYR C CD2 1 
ATOM   3883 C CE1 . TYR C 1 39  ? -23.267 -14.249 -16.952 1.00 22.95 ? 39  TYR C CE1 1 
ATOM   3884 C CE2 . TYR C 1 39  ? -20.935 -14.024 -16.445 1.00 25.17 ? 39  TYR C CE2 1 
ATOM   3885 C CZ  . TYR C 1 39  ? -22.224 -13.523 -16.413 1.00 25.57 ? 39  TYR C CZ  1 
ATOM   3886 O OH  . TYR C 1 39  ? -22.471 -12.297 -15.824 1.00 23.63 ? 39  TYR C OH  1 
ATOM   3887 N N   . GLY C 1 40  ? -20.318 -17.281 -21.375 1.00 18.04 ? 40  GLY C N   1 
ATOM   3888 C CA  . GLY C 1 40  ? -19.423 -16.534 -22.240 1.00 15.21 ? 40  GLY C CA  1 
ATOM   3889 C C   . GLY C 1 40  ? -18.233 -16.020 -21.458 1.00 19.84 ? 40  GLY C C   1 
ATOM   3890 O O   . GLY C 1 40  ? -17.868 -14.852 -21.573 1.00 21.03 ? 40  GLY C O   1 
ATOM   3891 N N   . LYS C 1 41  ? -17.619 -16.889 -20.659 1.00 16.72 ? 41  LYS C N   1 
ATOM   3892 C CA  . LYS C 1 41  ? -16.490 -16.536 -19.807 1.00 18.39 ? 41  LYS C CA  1 
ATOM   3893 C C   . LYS C 1 41  ? -15.265 -17.329 -20.235 1.00 16.96 ? 41  LYS C C   1 
ATOM   3894 O O   . LYS C 1 41  ? -15.358 -18.543 -20.451 1.00 19.56 ? 41  LYS C O   1 
ATOM   3895 C CB  . LYS C 1 41  ? -16.819 -16.831 -18.344 1.00 15.63 ? 41  LYS C CB  1 
ATOM   3896 C CG  . LYS C 1 41  ? -15.773 -16.347 -17.359 1.00 20.31 ? 41  LYS C CG  1 
ATOM   3897 C CD  . LYS C 1 41  ? -16.346 -16.351 -15.963 1.00 25.74 ? 41  LYS C CD  1 
ATOM   3898 C CE  . LYS C 1 41  ? -15.507 -17.130 -15.000 1.00 38.08 ? 41  LYS C CE  1 
ATOM   3899 N NZ  . LYS C 1 41  ? -14.784 -16.173 -14.117 1.00 36.30 ? 41  LYS C NZ  1 
ATOM   3900 N N   . LEU C 1 42  ? -14.130 -16.636 -20.350 1.00 14.74 ? 42  LEU C N   1 
ATOM   3901 C CA  . LEU C 1 42  ? -12.830 -17.193 -20.703 1.00 21.51 ? 42  LEU C CA  1 
ATOM   3902 C C   . LEU C 1 42  ? -11.817 -16.769 -19.650 1.00 19.55 ? 42  LEU C C   1 
ATOM   3903 O O   . LEU C 1 42  ? -11.723 -15.581 -19.330 1.00 18.49 ? 42  LEU C O   1 
ATOM   3904 C CB  . LEU C 1 42  ? -12.359 -16.665 -22.064 1.00 19.61 ? 42  LEU C CB  1 
ATOM   3905 C CG  . LEU C 1 42  ? -13.125 -16.997 -23.334 1.00 23.50 ? 42  LEU C CG  1 
ATOM   3906 C CD1 . LEU C 1 42  ? -12.404 -16.385 -24.516 1.00 27.74 ? 42  LEU C CD1 1 
ATOM   3907 C CD2 . LEU C 1 42  ? -13.118 -18.491 -23.463 1.00 25.34 ? 42  LEU C CD2 1 
ATOM   3908 N N   . THR C 1 43  ? -11.037 -17.718 -19.136 1.00 16.51 ? 43  THR C N   1 
ATOM   3909 C CA  . THR C 1 43  ? -9.883  -17.399 -18.295 1.00 18.46 ? 43  THR C CA  1 
ATOM   3910 C C   . THR C 1 43  ? -8.676  -18.167 -18.814 1.00 20.14 ? 43  THR C C   1 
ATOM   3911 O O   . THR C 1 43  ? -8.727  -19.395 -18.935 1.00 16.69 ? 43  THR C O   1 
ATOM   3912 C CB  . THR C 1 43  ? -10.157 -17.715 -16.814 1.00 21.95 ? 43  THR C CB  1 
ATOM   3913 O OG1 . THR C 1 43  ? -10.072 -19.123 -16.603 1.00 27.31 ? 43  THR C OG1 1 
ATOM   3914 C CG2 . THR C 1 43  ? -11.527 -17.206 -16.366 1.00 21.48 ? 43  THR C CG2 1 
ATOM   3915 N N   . LEU C 1 44  ? -7.602  -17.438 -19.139 1.00 14.75 ? 44  LEU C N   1 
ATOM   3916 C CA  . LEU C 1 44  ? -6.418  -17.974 -19.788 1.00 14.82 ? 44  LEU C CA  1 
ATOM   3917 C C   . LEU C 1 44  ? -5.171  -17.306 -19.229 1.00 16.02 ? 44  LEU C C   1 
ATOM   3918 O O   . LEU C 1 44  ? -5.184  -16.118 -18.906 1.00 16.71 ? 44  LEU C O   1 
ATOM   3919 C CB  . LEU C 1 44  ? -6.481  -17.747 -21.310 1.00 17.54 ? 44  LEU C CB  1 
ATOM   3920 C CG  . LEU C 1 44  ? -7.570  -18.562 -22.013 1.00 18.17 ? 44  LEU C CG  1 
ATOM   3921 C CD1 . LEU C 1 44  ? -7.986  -17.911 -23.303 1.00 17.14 ? 44  LEU C CD1 1 
ATOM   3922 C CD2 . LEU C 1 44  ? -6.985  -19.918 -22.311 1.00 16.95 ? 44  LEU C CD2 1 
ATOM   3923 N N   . LYS C 1 45  ? -4.093  -18.070 -19.118 1.00 13.28 ? 45  LYS C N   1 
ATOM   3924 C CA  . LYS C 1 45  ? -2.778  -17.510 -18.853 1.00 14.35 ? 45  LYS C CA  1 
ATOM   3925 C C   . LYS C 1 45  ? -1.859  -17.877 -20.007 1.00 17.27 ? 45  LYS C C   1 
ATOM   3926 O O   . LYS C 1 45  ? -1.778  -19.051 -20.396 1.00 14.28 ? 45  LYS C O   1 
ATOM   3927 C CB  . LYS C 1 45  ? -2.202  -18.011 -17.525 1.00 16.04 ? 45  LYS C CB  1 
ATOM   3928 C CG  . LYS C 1 45  ? -0.783  -17.517 -17.260 1.00 16.56 ? 45  LYS C CG  1 
ATOM   3929 C CD  . LYS C 1 45  ? -0.284  -18.035 -15.920 1.00 20.37 ? 45  LYS C CD  1 
ATOM   3930 C CE  . LYS C 1 45  ? 1.200   -17.748 -15.740 1.00 20.85 ? 45  LYS C CE  1 
ATOM   3931 N NZ  . LYS C 1 45  ? 1.758   -18.435 -14.516 1.00 20.98 ? 45  LYS C NZ  1 
ATOM   3932 N N   . PHE C 1 46  ? -1.171  -16.884 -20.552 1.00 13.37 ? 46  PHE C N   1 
ATOM   3933 C CA  . PHE C 1 46  ? -0.270  -17.101 -21.671 1.00 14.98 ? 46  PHE C CA  1 
ATOM   3934 C C   . PHE C 1 46  ? 1.162   -16.878 -21.216 1.00 15.87 ? 46  PHE C C   1 
ATOM   3935 O O   . PHE C 1 46  ? 1.441   -15.945 -20.454 1.00 15.26 ? 46  PHE C O   1 
ATOM   3936 C CB  . PHE C 1 46  ? -0.596  -16.148 -22.823 1.00 12.41 ? 46  PHE C CB  1 
ATOM   3937 C CG  . PHE C 1 46  ? -1.966  -16.334 -23.376 1.00 13.14 ? 46  PHE C CG  1 
ATOM   3938 C CD1 . PHE C 1 46  ? -2.202  -17.210 -24.433 1.00 12.06 ? 46  PHE C CD1 1 
ATOM   3939 C CD2 . PHE C 1 46  ? -3.029  -15.625 -22.831 1.00 14.12 ? 46  PHE C CD2 1 
ATOM   3940 C CE1 . PHE C 1 46  ? -3.474  -17.370 -24.929 1.00 11.95 ? 46  PHE C CE1 1 
ATOM   3941 C CE2 . PHE C 1 46  ? -4.312  -15.778 -23.317 1.00 14.29 ? 46  PHE C CE2 1 
ATOM   3942 C CZ  . PHE C 1 46  ? -4.540  -16.652 -24.368 1.00 12.46 ? 46  PHE C CZ  1 
ATOM   3943 N N   . ILE C 1 47  ? 2.076   -17.698 -21.720 1.00 13.05 ? 47  ILE C N   1 
ATOM   3944 C CA  . ILE C 1 47  ? 3.497   -17.527 -21.458 1.00 14.91 ? 47  ILE C CA  1 
ATOM   3945 C C   . ILE C 1 47  ? 4.248   -17.447 -22.778 1.00 14.11 ? 47  ILE C C   1 
ATOM   3946 O O   . ILE C 1 47  ? 3.973   -18.213 -23.708 1.00 13.17 ? 47  ILE C O   1 
ATOM   3947 C CB  . ILE C 1 47  ? 4.022   -18.679 -20.576 1.00 18.05 ? 47  ILE C CB  1 
ATOM   3948 C CG1 . ILE C 1 47  ? 3.294   -18.643 -19.224 1.00 19.99 ? 47  ILE C CG1 1 
ATOM   3949 C CG2 . ILE C 1 47  ? 5.528   -18.589 -20.390 1.00 18.66 ? 47  ILE C CG2 1 
ATOM   3950 C CD1 . ILE C 1 47  ? 3.851   -19.595 -18.180 1.00 27.76 ? 47  ILE C CD1 1 
ATOM   3951 N N   . CYS C 1 48  ? 5.192   -16.516 -22.874 1.00 11.67 ? 48  CYS C N   1 
ATOM   3952 C CA  . CYS C 1 48  ? 6.162   -16.592 -23.962 1.00 12.70 ? 48  CYS C CA  1 
ATOM   3953 C C   . CYS C 1 48  ? 7.196   -17.635 -23.569 1.00 16.52 ? 48  CYS C C   1 
ATOM   3954 O O   . CYS C 1 48  ? 8.031   -17.388 -22.694 1.00 16.22 ? 48  CYS C O   1 
ATOM   3955 C CB  . CYS C 1 48  ? 6.840   -15.252 -24.229 1.00 13.25 ? 48  CYS C CB  1 
ATOM   3956 S SG  . CYS C 1 48  ? 8.003   -15.360 -25.615 1.00 15.47 ? 48  CYS C SG  1 
ATOM   3957 N N   . THR C 1 49  ? 7.134   -18.799 -24.201 1.00 13.59 ? 49  THR C N   1 
ATOM   3958 C CA  . THR C 1 49  ? 7.965   -19.926 -23.801 1.00 15.86 ? 49  THR C CA  1 
ATOM   3959 C C   . THR C 1 49  ? 9.360   -19.884 -24.418 1.00 20.60 ? 49  THR C C   1 
ATOM   3960 O O   . THR C 1 49  ? 10.141  -20.827 -24.213 1.00 22.64 ? 49  THR C O   1 
ATOM   3961 C CB  . THR C 1 49  ? 7.278   -21.238 -24.192 1.00 13.83 ? 49  THR C CB  1 
ATOM   3962 O OG1 . THR C 1 49  ? 6.894   -21.186 -25.571 1.00 15.08 ? 49  THR C OG1 1 
ATOM   3963 C CG2 . THR C 1 49  ? 5.993   -21.443 -23.371 1.00 16.69 ? 49  THR C CG2 1 
ATOM   3964 N N   . THR C 1 50  ? 9.704   -18.837 -25.173 1.00 17.30 ? 50  THR C N   1 
ATOM   3965 C CA  . THR C 1 50  ? 11.022  -18.736 -25.792 1.00 18.16 ? 50  THR C CA  1 
ATOM   3966 C C   . THR C 1 50  ? 11.849  -17.588 -25.226 1.00 19.95 ? 50  THR C C   1 
ATOM   3967 O O   . THR C 1 50  ? 12.944  -17.320 -25.725 1.00 23.62 ? 50  THR C O   1 
ATOM   3968 C CB  . THR C 1 50  ? 10.886  -18.581 -27.309 1.00 15.54 ? 50  THR C CB  1 
ATOM   3969 O OG1 . THR C 1 50  ? 9.892   -17.595 -27.607 1.00 13.75 ? 50  THR C OG1 1 
ATOM   3970 C CG2 . THR C 1 50  ? 10.452  -19.918 -27.951 1.00 15.59 ? 50  THR C CG2 1 
ATOM   3971 N N   . GLY C 1 51  ? 11.348  -16.891 -24.206 1.00 16.23 ? 51  GLY C N   1 
ATOM   3972 C CA  . GLY C 1 51  ? 12.041  -15.758 -23.621 1.00 20.46 ? 51  GLY C CA  1 
ATOM   3973 C C   . GLY C 1 51  ? 11.151  -14.525 -23.595 1.00 18.93 ? 51  GLY C C   1 
ATOM   3974 O O   . GLY C 1 51  ? 9.954   -14.615 -23.311 1.00 20.73 ? 51  GLY C O   1 
ATOM   3975 N N   . LYS C 1 52  ? 11.745  -13.380 -23.896 1.00 19.52 ? 52  LYS C N   1 
ATOM   3976 C CA  . LYS C 1 52  ? 10.989  -12.138 -23.956 1.00 19.99 ? 52  LYS C CA  1 
ATOM   3977 C C   . LYS C 1 52  ? 10.153  -12.096 -25.235 1.00 18.61 ? 52  LYS C C   1 
ATOM   3978 O O   . LYS C 1 52  ? 10.665  -12.319 -26.335 1.00 18.22 ? 52  LYS C O   1 
ATOM   3979 C CB  . LYS C 1 52  ? 11.952  -10.943 -23.901 1.00 21.60 ? 52  LYS C CB  1 
ATOM   3980 C CG  . LYS C 1 52  ? 11.410  -9.672  -23.230 1.00 30.20 ? 52  LYS C CG  1 
ATOM   3981 C CD  . LYS C 1 52  ? 10.137  -9.165  -23.910 1.00 30.56 ? 52  LYS C CD  1 
ATOM   3982 C CE  . LYS C 1 52  ? 9.323   -8.167  -23.063 1.00 30.60 ? 52  LYS C CE  1 
ATOM   3983 N NZ  . LYS C 1 52  ? 7.884   -8.158  -23.498 1.00 26.16 ? 52  LYS C NZ  1 
ATOM   3984 N N   . LEU C 1 53  ? 8.869   -11.795 -25.094 1.00 16.05 ? 53  LEU C N   1 
ATOM   3985 C CA  . LEU C 1 53  ? 8.013   -11.553 -26.254 1.00 16.59 ? 53  LEU C CA  1 
ATOM   3986 C C   . LEU C 1 53  ? 8.522   -10.365 -27.059 1.00 16.89 ? 53  LEU C C   1 
ATOM   3987 O O   . LEU C 1 53  ? 8.612   -9.262  -26.514 1.00 18.22 ? 53  LEU C O   1 
ATOM   3988 C CB  . LEU C 1 53  ? 6.589   -11.269 -25.807 1.00 14.09 ? 53  LEU C CB  1 
ATOM   3989 C CG  . LEU C 1 53  ? 5.536   -11.463 -26.898 1.00 13.77 ? 53  LEU C CG  1 
ATOM   3990 C CD1 . LEU C 1 53  ? 5.481   -12.940 -27.301 1.00 16.09 ? 53  LEU C CD1 1 
ATOM   3991 C CD2 . LEU C 1 53  ? 4.209   -11.003 -26.354 1.00 13.35 ? 53  LEU C CD2 1 
ATOM   3992 N N   . PRO C 1 54  ? 8.833   -10.526 -28.345 1.00 14.99 ? 54  PRO C N   1 
ATOM   3993 C CA  . PRO C 1 54  ? 9.360   -9.394  -29.117 1.00 17.60 ? 54  PRO C CA  1 
ATOM   3994 C C   . PRO C 1 54  ? 8.307   -8.407  -29.613 1.00 18.16 ? 54  PRO C C   1 
ATOM   3995 O O   . PRO C 1 54  ? 8.674   -7.458  -30.316 1.00 19.12 ? 54  PRO C O   1 
ATOM   3996 C CB  . PRO C 1 54  ? 10.070  -10.077 -30.286 1.00 16.67 ? 54  PRO C CB  1 
ATOM   3997 C CG  . PRO C 1 54  ? 9.342   -11.365 -30.476 1.00 19.92 ? 54  PRO C CG  1 
ATOM   3998 C CD  . PRO C 1 54  ? 8.794   -11.775 -29.133 1.00 17.02 ? 54  PRO C CD  1 
ATOM   3999 N N   . VAL C 1 55  ? 7.033   -8.602  -29.276 1.00 16.00 ? 55  VAL C N   1 
ATOM   4000 C CA  . VAL C 1 55  ? 5.954   -7.665  -29.597 1.00 16.36 ? 55  VAL C CA  1 
ATOM   4001 C C   . VAL C 1 55  ? 5.173   -7.428  -28.308 1.00 15.57 ? 55  VAL C C   1 
ATOM   4002 O O   . VAL C 1 55  ? 5.358   -8.174  -27.331 1.00 14.77 ? 55  VAL C O   1 
ATOM   4003 C CB  . VAL C 1 55  ? 5.031   -8.190  -30.710 1.00 14.30 ? 55  VAL C CB  1 
ATOM   4004 C CG1 . VAL C 1 55  ? 5.799   -8.435  -32.030 1.00 15.64 ? 55  VAL C CG1 1 
ATOM   4005 C CG2 . VAL C 1 55  ? 4.299   -9.447  -30.250 1.00 12.37 ? 55  VAL C CG2 1 
ATOM   4006 N N   . PRO C 1 56  ? 4.311   -6.411  -28.231 1.00 13.89 ? 56  PRO C N   1 
ATOM   4007 C CA  . PRO C 1 56  ? 3.516   -6.239  -27.007 1.00 12.84 ? 56  PRO C CA  1 
ATOM   4008 C C   . PRO C 1 56  ? 2.396   -7.261  -26.910 1.00 11.10 ? 56  PRO C C   1 
ATOM   4009 O O   . PRO C 1 56  ? 1.747   -7.605  -27.902 1.00 13.32 ? 56  PRO C O   1 
ATOM   4010 C CB  . PRO C 1 56  ? 2.975   -4.802  -27.109 1.00 13.36 ? 56  PRO C CB  1 
ATOM   4011 C CG  . PRO C 1 56  ? 3.780   -4.139  -28.189 1.00 13.50 ? 56  PRO C CG  1 
ATOM   4012 C CD  . PRO C 1 56  ? 4.259   -5.234  -29.112 1.00 11.36 ? 56  PRO C CD  1 
ATOM   4013 N N   . TRP C 1 57  ? 2.203   -7.762  -25.694 1.00 12.74 ? 57  TRP C N   1 
ATOM   4014 C CA  . TRP C 1 57  ? 1.121   -8.706  -25.402 1.00 13.42 ? 57  TRP C CA  1 
ATOM   4015 C C   . TRP C 1 57  ? -0.236  -8.262  -25.927 1.00 12.23 ? 57  TRP C C   1 
ATOM   4016 O O   . TRP C 1 57  ? -0.941  -9.102  -26.508 1.00 13.13 ? 57  TRP C O   1 
ATOM   4017 C CB  . TRP C 1 57  ? 1.039   -8.975  -23.891 1.00 13.33 ? 57  TRP C CB  1 
ATOM   4018 C CG  . TRP C 1 57  ? 2.048   -9.973  -23.397 1.00 13.89 ? 57  TRP C CG  1 
ATOM   4019 C CD1 . TRP C 1 57  ? 3.132   -9.741  -22.596 1.00 15.86 ? 57  TRP C CD1 1 
ATOM   4020 C CD2 . TRP C 1 57  ? 2.067   -11.370 -23.701 1.00 13.14 ? 57  TRP C CD2 1 
ATOM   4021 N NE1 . TRP C 1 57  ? 3.823   -10.913 -22.380 1.00 15.33 ? 57  TRP C NE1 1 
ATOM   4022 C CE2 . TRP C 1 57  ? 3.190   -11.929 -23.042 1.00 13.79 ? 57  TRP C CE2 1 
ATOM   4023 C CE3 . TRP C 1 57  ? 1.251   -12.201 -24.468 1.00 9.83  ? 57  TRP C CE3 1 
ATOM   4024 C CZ2 . TRP C 1 57  ? 3.507   -13.286 -23.129 1.00 15.21 ? 57  TRP C CZ2 1 
ATOM   4025 C CZ3 . TRP C 1 57  ? 1.566   -13.547 -24.554 1.00 15.64 ? 57  TRP C CZ3 1 
ATOM   4026 C CH2 . TRP C 1 57  ? 2.685   -14.078 -23.891 1.00 14.43 ? 57  TRP C CH2 1 
ATOM   4027 N N   . PRO C 1 58  ? -0.671  -7.003  -25.763 1.00 12.61 ? 58  PRO C N   1 
ATOM   4028 C CA  . PRO C 1 58  ? -1.986  -6.618  -26.312 1.00 11.79 ? 58  PRO C CA  1 
ATOM   4029 C C   . PRO C 1 58  ? -2.135  -6.824  -27.819 1.00 14.20 ? 58  PRO C C   1 
ATOM   4030 O O   . PRO C 1 58  ? -3.267  -7.011  -28.294 1.00 13.07 ? 58  PRO C O   1 
ATOM   4031 C CB  . PRO C 1 58  ? -2.104  -5.124  -25.942 1.00 14.51 ? 58  PRO C CB  1 
ATOM   4032 C CG  . PRO C 1 58  ? -1.199  -4.949  -24.748 1.00 14.44 ? 58  PRO C CG  1 
ATOM   4033 C CD  . PRO C 1 58  ? -0.043  -5.891  -25.014 1.00 12.09 ? 58  PRO C CD  1 
ATOM   4034 N N   . THR C 1 59  ? -1.049  -6.793  -28.596 1.00 12.59 ? 59  THR C N   1 
ATOM   4035 C CA  . THR C 1 59  ? -1.228  -6.961  -30.036 1.00 12.08 ? 59  THR C CA  1 
ATOM   4036 C C   . THR C 1 59  ? -1.561  -8.392  -30.426 1.00 13.54 ? 59  THR C C   1 
ATOM   4037 O O   . THR C 1 59  ? -1.965  -8.617  -31.575 1.00 12.61 ? 59  THR C O   1 
ATOM   4038 C CB  . THR C 1 59  ? 0.011   -6.513  -30.804 1.00 11.96 ? 59  THR C CB  1 
ATOM   4039 O OG1 . THR C 1 59  ? 1.098   -7.414  -30.551 1.00 11.45 ? 59  THR C OG1 1 
ATOM   4040 C CG2 . THR C 1 59  ? 0.410   -5.109  -30.378 1.00 13.09 ? 59  THR C CG2 1 
ATOM   4041 N N   . LEU C 1 60  ? -1.431  -9.354  -29.507 1.00 11.57 ? 60  LEU C N   1 
ATOM   4042 C CA  . LEU C 1 60  ? -1.732  -10.750 -29.792 1.00 10.44 ? 60  LEU C CA  1 
ATOM   4043 C C   . LEU C 1 60  ? -3.088  -11.201 -29.264 1.00 9.82  ? 60  LEU C C   1 
ATOM   4044 O O   . LEU C 1 60  ? -3.494  -12.339 -29.538 1.00 12.52 ? 60  LEU C O   1 
ATOM   4045 C CB  . LEU C 1 60  ? -0.649  -11.670 -29.210 1.00 9.53  ? 60  LEU C CB  1 
ATOM   4046 C CG  . LEU C 1 60  ? 0.789   -11.475 -29.677 1.00 13.03 ? 60  LEU C CG  1 
ATOM   4047 C CD1 . LEU C 1 60  ? 1.729   -12.448 -28.958 1.00 11.67 ? 60  LEU C CD1 1 
ATOM   4048 C CD2 . LEU C 1 60  ? 0.893   -11.639 -31.178 1.00 11.01 ? 60  LEU C CD2 1 
ATOM   4049 N N   . VAL C 1 61  ? -3.807  -10.351 -28.528 1.00 10.35 ? 61  VAL C N   1 
ATOM   4050 C CA  . VAL C 1 61  ? -5.029  -10.805 -27.863 1.00 9.76  ? 61  VAL C CA  1 
ATOM   4051 C C   . VAL C 1 61  ? -6.019  -11.373 -28.874 1.00 9.14  ? 61  VAL C C   1 
ATOM   4052 O O   . VAL C 1 61  ? -6.567  -12.461 -28.677 1.00 10.72 ? 61  VAL C O   1 
ATOM   4053 C CB  . VAL C 1 61  ? -5.662  -9.662  -27.047 1.00 13.04 ? 61  VAL C CB  1 
ATOM   4054 C CG1 . VAL C 1 61  ? -7.128  -10.007 -26.723 1.00 14.19 ? 61  VAL C CG1 1 
ATOM   4055 C CG2 . VAL C 1 61  ? -4.866  -9.399  -25.776 1.00 13.10 ? 61  VAL C CG2 1 
ATOM   4056 N N   . THR C 1 62  ? -6.280  -10.643 -29.973 1.00 9.65  ? 62  THR C N   1 
ATOM   4057 C CA  . THR C 1 62  ? -7.275  -11.138 -30.928 1.00 9.79  ? 62  THR C CA  1 
ATOM   4058 C C   . THR C 1 62  ? -6.836  -12.446 -31.580 1.00 9.32  ? 62  THR C C   1 
ATOM   4059 O O   . THR C 1 62  ? -7.680  -13.267 -31.968 1.00 10.66 ? 62  THR C O   1 
ATOM   4060 C CB  . THR C 1 62  ? -7.553  -10.117 -32.034 1.00 8.84  ? 62  THR C CB  1 
ATOM   4061 O OG1 . THR C 1 62  ? -6.322  -9.592  -32.549 1.00 10.95 ? 62  THR C OG1 1 
ATOM   4062 C CG2 . THR C 1 62  ? -8.438  -8.979  -31.511 1.00 11.33 ? 62  THR C CG2 1 
ATOM   4063 N N   . THR C 1 63  ? -5.532  -12.650 -31.733 1.00 10.72 ? 63  THR C N   1 
ATOM   4064 C CA  . THR C 1 63  ? -5.054  -13.875 -32.370 1.00 8.41  ? 63  THR C CA  1 
ATOM   4065 C C   . THR C 1 63  ? -5.185  -15.069 -31.431 1.00 11.68 ? 63  THR C C   1 
ATOM   4066 O O   . THR C 1 63  ? -5.628  -16.154 -31.844 1.00 12.00 ? 63  THR C O   1 
ATOM   4067 C CB  . THR C 1 63  ? -3.604  -13.690 -32.811 1.00 10.34 ? 63  THR C CB  1 
ATOM   4068 O OG1 . THR C 1 63  ? -3.540  -12.664 -33.812 1.00 12.04 ? 63  THR C OG1 1 
ATOM   4069 C CG2 . THR C 1 63  ? -3.052  -14.971 -33.402 1.00 11.43 ? 63  THR C CG2 1 
ATOM   4070 N N   . LEU C 1 64  ? -4.806  -14.880 -30.171 1.00 9.59  ? 64  LEU C N   1 
ATOM   4071 C CA  . LEU C 1 64  ? -4.869  -15.891 -29.121 1.00 9.82  ? 64  LEU C CA  1 
ATOM   4072 C C   . LEU C 1 64  ? -6.306  -16.202 -28.722 1.00 13.20 ? 64  LEU C C   1 
ATOM   4073 O O   . LEU C 1 64  ? -6.665  -17.357 -28.455 1.00 11.25 ? 64  LEU C O   1 
ATOM   4074 C CB  . LEU C 1 64  ? -4.074  -15.399 -27.902 1.00 8.66  ? 64  LEU C CB  1 
ATOM   4075 C CG  . LEU C 1 64  ? -2.609  -15.091 -28.177 1.00 7.61  ? 64  LEU C CG  1 
ATOM   4076 C CD1 . LEU C 1 64  ? -2.010  -14.306 -26.993 1.00 10.81 ? 64  LEU C CD1 1 
ATOM   4077 C CD2 . LEU C 1 64  ? -1.830  -16.415 -28.373 1.00 8.56  ? 64  LEU C CD2 1 
HETATM 4078 N N1  . CRO C 1 65  ? -6.998  -14.970 -28.690 1.00 17.99 ? 66  CRO C N1  1 
HETATM 4079 C CA1 . CRO C 1 65  ? -8.358  -15.244 -28.333 1.00 20.90 ? 66  CRO C CA1 1 
HETATM 4080 C CB1 . CRO C 1 65  ? -8.764  -14.833 -26.924 1.00 23.20 ? 66  CRO C CB1 1 
HETATM 4081 C CG1 . CRO C 1 65  ? -8.183  -15.763 -25.894 1.00 24.40 ? 66  CRO C CG1 1 
HETATM 4082 O OG1 . CRO C 1 65  ? -8.615  -13.739 -26.667 1.00 24.62 ? 66  CRO C OG1 1 
HETATM 4083 C C1  . CRO C 1 65  ? -9.327  -14.752 -29.398 1.00 21.76 ? 66  CRO C C1  1 
HETATM 4084 N N2  . CRO C 1 65  ? -9.908  -13.610 -29.334 1.00 22.47 ? 66  CRO C N2  1 
HETATM 4085 N N3  . CRO C 1 65  ? -9.560  -15.269 -30.557 1.00 23.25 ? 66  CRO C N3  1 
HETATM 4086 C C2  . CRO C 1 65  ? -10.262 -14.430 -31.232 1.00 21.79 ? 66  CRO C C2  1 
HETATM 4087 O O2  . CRO C 1 65  ? -10.683 -14.602 -32.513 1.00 18.00 ? 66  CRO C O2  1 
HETATM 4088 C CA2 . CRO C 1 65  ? -10.495 -13.354 -30.440 1.00 21.45 ? 66  CRO C CA2 1 
HETATM 4089 C CA3 . CRO C 1 65  ? -9.109  -16.510 -31.085 1.00 20.45 ? 66  CRO C CA3 1 
HETATM 4090 C C3  . CRO C 1 65  ? -10.110 -17.664 -30.936 1.00 23.06 ? 66  CRO C C3  1 
HETATM 4091 O O3  . CRO C 1 65  ? -9.899  -18.591 -31.602 1.00 21.42 ? 66  CRO C O3  1 
HETATM 4092 C CB2 . CRO C 1 65  ? -11.359 -12.178 -30.867 1.00 22.13 ? 66  CRO C CB2 1 
HETATM 4093 C CG2 . CRO C 1 65  ? -11.472 -10.899 -30.067 1.00 23.78 ? 66  CRO C CG2 1 
HETATM 4094 C CD1 . CRO C 1 65  ? -10.989 -10.667 -28.800 1.00 24.17 ? 66  CRO C CD1 1 
HETATM 4095 C CD2 . CRO C 1 65  ? -12.125 -9.881  -30.698 1.00 25.01 ? 66  CRO C CD2 1 
HETATM 4096 C CE1 . CRO C 1 65  ? -11.178 -9.451  -28.210 1.00 18.44 ? 66  CRO C CE1 1 
HETATM 4097 C CE2 . CRO C 1 65  ? -12.302 -8.663  -30.134 1.00 21.78 ? 66  CRO C CE2 1 
HETATM 4098 C CZ  . CRO C 1 65  ? -11.835 -8.448  -28.878 1.00 24.82 ? 66  CRO C CZ  1 
HETATM 4099 O OH  . CRO C 1 65  ? -12.033 -7.217  -28.331 1.00 24.68 ? 66  CRO C OH  1 
ATOM   4100 N N   . VAL C 1 66  ? -10.969 -17.431 -29.863 1.00 13.49 ? 68  VAL C N   1 
ATOM   4101 C CA  . VAL C 1 66  ? -11.628 -18.699 -29.796 1.00 12.01 ? 68  VAL C CA  1 
ATOM   4102 C C   . VAL C 1 66  ? -13.106 -18.286 -29.608 1.00 15.08 ? 68  VAL C C   1 
ATOM   4103 O O   . VAL C 1 66  ? -13.715 -18.445 -28.541 1.00 12.04 ? 68  VAL C O   1 
ATOM   4104 C CB  . VAL C 1 66  ? -11.132 -19.503 -28.546 1.00 13.15 ? 68  VAL C CB  1 
ATOM   4105 C CG1 . VAL C 1 66  ? -9.876  -20.326 -28.890 1.00 13.01 ? 68  VAL C CG1 1 
ATOM   4106 C CG2 . VAL C 1 66  ? -10.889 -18.608 -27.312 1.00 13.26 ? 68  VAL C CG2 1 
ATOM   4107 N N   . GLN C 1 67  ? -13.703 -17.779 -30.680 1.00 15.42 ? 69  GLN C N   1 
ATOM   4108 C CA  . GLN C 1 67  ? -15.041 -17.201 -30.626 1.00 14.66 ? 69  GLN C CA  1 
ATOM   4109 C C   . GLN C 1 67  ? -16.129 -18.250 -30.465 1.00 15.59 ? 69  GLN C C   1 
ATOM   4110 O O   . GLN C 1 67  ? -17.290 -17.878 -30.267 1.00 14.08 ? 69  GLN C O   1 
ATOM   4111 C CB  . GLN C 1 67  ? -15.260 -16.351 -31.881 1.00 14.88 ? 69  GLN C CB  1 
ATOM   4112 C CG  . GLN C 1 67  ? -14.244 -15.192 -31.968 1.00 18.00 ? 69  GLN C CG  1 
ATOM   4113 C CD  . GLN C 1 67  ? -14.239 -14.479 -33.302 1.00 14.45 ? 69  GLN C CD  1 
ATOM   4114 O OE1 . GLN C 1 67  ? -14.059 -15.112 -34.346 1.00 15.21 ? 69  GLN C OE1 1 
ATOM   4115 N NE2 . GLN C 1 67  ? -14.351 -13.147 -33.275 1.00 14.82 ? 69  GLN C NE2 1 
ATOM   4116 N N   . CYS C 1 68  ? -15.777 -19.546 -30.495 1.00 14.80 ? 70  CYS C N   1 
ATOM   4117 C CA  . CYS C 1 68  ? -16.718 -20.604 -30.136 1.00 14.47 ? 70  CYS C CA  1 
ATOM   4118 C C   . CYS C 1 68  ? -17.159 -20.524 -28.676 1.00 15.62 ? 70  CYS C C   1 
ATOM   4119 O O   . CYS C 1 68  ? -18.133 -21.180 -28.296 1.00 16.81 ? 70  CYS C O   1 
ATOM   4120 C CB  . CYS C 1 68  ? -16.101 -21.988 -30.407 1.00 14.00 ? 70  CYS C CB  1 
ATOM   4121 S SG  . CYS C 1 68  ? -14.404 -22.183 -29.778 1.00 15.60 ? 70  CYS C SG  1 
ATOM   4122 N N   . PHE C 1 69  ? -16.466 -19.765 -27.842 1.00 14.90 ? 71  PHE C N   1 
ATOM   4123 C CA  . PHE C 1 69  ? -16.879 -19.632 -26.454 1.00 14.44 ? 71  PHE C CA  1 
ATOM   4124 C C   . PHE C 1 69  ? -17.791 -18.445 -26.227 1.00 15.48 ? 71  PHE C C   1 
ATOM   4125 O O   . PHE C 1 69  ? -18.201 -18.210 -25.087 1.00 14.63 ? 71  PHE C O   1 
ATOM   4126 C CB  . PHE C 1 69  ? -15.658 -19.531 -25.545 1.00 17.62 ? 71  PHE C CB  1 
ATOM   4127 C CG  . PHE C 1 69  ? -14.986 -20.855 -25.331 1.00 13.20 ? 71  PHE C CG  1 
ATOM   4128 C CD1 . PHE C 1 69  ? -15.541 -21.782 -24.469 1.00 14.54 ? 71  PHE C CD1 1 
ATOM   4129 C CD2 . PHE C 1 69  ? -13.841 -21.187 -26.026 1.00 15.18 ? 71  PHE C CD2 1 
ATOM   4130 C CE1 . PHE C 1 69  ? -14.937 -23.035 -24.285 1.00 15.17 ? 71  PHE C CE1 1 
ATOM   4131 C CE2 . PHE C 1 69  ? -13.244 -22.427 -25.856 1.00 14.70 ? 71  PHE C CE2 1 
ATOM   4132 C CZ  . PHE C 1 69  ? -13.792 -23.344 -24.967 1.00 13.33 ? 71  PHE C CZ  1 
ATOM   4133 N N   . SER C 1 70  ? -18.138 -17.708 -27.279 1.00 14.81 ? 72  SER C N   1 
ATOM   4134 C CA  . SER C 1 70  ? -19.039 -16.583 -27.094 1.00 16.72 ? 72  SER C CA  1 
ATOM   4135 C C   . SER C 1 70  ? -20.406 -17.087 -26.656 1.00 19.35 ? 72  SER C C   1 
ATOM   4136 O O   . SER C 1 70  ? -20.867 -18.154 -27.081 1.00 18.31 ? 72  SER C O   1 
ATOM   4137 C CB  . SER C 1 70  ? -19.149 -15.772 -28.381 1.00 17.92 ? 72  SER C CB  1 
ATOM   4138 O OG  . SER C 1 70  ? -19.617 -16.581 -29.423 1.00 33.02 ? 72  SER C OG  1 
ATOM   4139 N N   . ARG C 1 71  ? -21.035 -16.338 -25.757 1.00 19.85 ? 73  ARG C N   1 
ATOM   4140 C CA  . ARG C 1 71  ? -22.359 -16.727 -25.311 1.00 20.76 ? 73  ARG C CA  1 
ATOM   4141 C C   . ARG C 1 71  ? -23.376 -16.379 -26.391 1.00 25.45 ? 73  ARG C C   1 
ATOM   4142 O O   . ARG C 1 71  ? -23.566 -15.204 -26.729 1.00 24.13 ? 73  ARG C O   1 
ATOM   4143 C CB  . ARG C 1 71  ? -22.705 -16.077 -23.971 1.00 21.14 ? 73  ARG C CB  1 
ATOM   4144 C CG  . ARG C 1 71  ? -23.827 -16.844 -23.292 1.00 26.60 ? 73  ARG C CG  1 
ATOM   4145 C CD  . ARG C 1 71  ? -25.239 -16.430 -23.644 1.00 34.32 ? 73  ARG C CD  1 
ATOM   4146 N NE  . ARG C 1 71  ? -25.512 -15.012 -23.461 1.00 37.64 ? 73  ARG C NE  1 
ATOM   4147 C CZ  . ARG C 1 71  ? -26.436 -14.537 -22.643 1.00 41.00 ? 73  ARG C CZ  1 
ATOM   4148 N NH1 . ARG C 1 71  ? -27.313 -15.337 -22.040 1.00 41.75 ? 73  ARG C NH1 1 
ATOM   4149 N NH2 . ARG C 1 71  ? -26.517 -13.225 -22.474 1.00 38.17 ? 73  ARG C NH2 1 
ATOM   4150 N N   . TYR C 1 72  ? -23.999 -17.413 -26.964 1.00 23.18 ? 74  TYR C N   1 
ATOM   4151 C CA  . TYR C 1 72  ? -25.072 -17.225 -27.927 1.00 28.06 ? 74  TYR C CA  1 
ATOM   4152 C C   . TYR C 1 72  ? -26.387 -17.475 -27.205 1.00 31.60 ? 74  TYR C C   1 
ATOM   4153 O O   . TYR C 1 72  ? -26.646 -18.616 -26.803 1.00 29.25 ? 74  TYR C O   1 
ATOM   4154 C CB  . TYR C 1 72  ? -24.917 -18.177 -29.118 1.00 24.89 ? 74  TYR C CB  1 
ATOM   4155 C CG  . TYR C 1 72  ? -24.060 -17.624 -30.242 1.00 23.14 ? 74  TYR C CG  1 
ATOM   4156 C CD1 . TYR C 1 72  ? -22.675 -17.615 -30.148 1.00 25.02 ? 74  TYR C CD1 1 
ATOM   4157 C CD2 . TYR C 1 72  ? -24.635 -17.122 -31.405 1.00 25.03 ? 74  TYR C CD2 1 
ATOM   4158 C CE1 . TYR C 1 72  ? -21.888 -17.108 -31.172 1.00 21.17 ? 74  TYR C CE1 1 
ATOM   4159 C CE2 . TYR C 1 72  ? -23.846 -16.609 -32.442 1.00 25.76 ? 74  TYR C CE2 1 
ATOM   4160 C CZ  . TYR C 1 72  ? -22.474 -16.603 -32.311 1.00 23.81 ? 74  TYR C CZ  1 
ATOM   4161 O OH  . TYR C 1 72  ? -21.666 -16.106 -33.309 1.00 22.06 ? 74  TYR C OH  1 
ATOM   4162 N N   . PRO C 1 73  ? -27.214 -16.460 -26.965 1.00 33.61 ? 75  PRO C N   1 
ATOM   4163 C CA  . PRO C 1 73  ? -28.511 -16.717 -26.322 1.00 39.82 ? 75  PRO C CA  1 
ATOM   4164 C C   . PRO C 1 73  ? -29.347 -17.630 -27.206 1.00 39.22 ? 75  PRO C C   1 
ATOM   4165 O O   . PRO C 1 73  ? -29.181 -17.668 -28.426 1.00 37.15 ? 75  PRO C O   1 
ATOM   4166 C CB  . PRO C 1 73  ? -29.142 -15.326 -26.173 1.00 38.93 ? 75  PRO C CB  1 
ATOM   4167 C CG  . PRO C 1 73  ? -28.151 -14.335 -26.690 1.00 37.33 ? 75  PRO C CG  1 
ATOM   4168 C CD  . PRO C 1 73  ? -26.896 -15.028 -27.102 1.00 33.51 ? 75  PRO C CD  1 
ATOM   4169 N N   . ASP C 1 74  ? -30.238 -18.395 -26.577 1.00 42.24 ? 76  ASP C N   1 
ATOM   4170 C CA  . ASP C 1 74  ? -30.851 -19.504 -27.298 1.00 44.75 ? 76  ASP C CA  1 
ATOM   4171 C C   . ASP C 1 74  ? -31.833 -19.053 -28.375 1.00 39.32 ? 76  ASP C C   1 
ATOM   4172 O O   . ASP C 1 74  ? -32.137 -19.843 -29.275 1.00 44.70 ? 76  ASP C O   1 
ATOM   4173 C CB  . ASP C 1 74  ? -31.504 -20.478 -26.314 1.00 49.02 ? 76  ASP C CB  1 
ATOM   4174 C CG  . ASP C 1 74  ? -32.210 -19.781 -25.185 1.00 54.12 ? 76  ASP C CG  1 
ATOM   4175 O OD1 . ASP C 1 74  ? -32.431 -18.554 -25.286 1.00 56.90 ? 76  ASP C OD1 1 
ATOM   4176 O OD2 . ASP C 1 74  ? -32.517 -20.459 -24.180 1.00 59.32 ? 76  ASP C OD2 1 
ATOM   4177 N N   . HIS C 1 75  ? -32.300 -17.803 -28.348 1.00 40.30 ? 77  HIS C N   1 
ATOM   4178 C CA  . HIS C 1 75  ? -33.004 -17.330 -29.537 1.00 41.66 ? 77  HIS C CA  1 
ATOM   4179 C C   . HIS C 1 75  ? -32.053 -17.088 -30.712 1.00 42.27 ? 77  HIS C C   1 
ATOM   4180 O O   . HIS C 1 75  ? -32.514 -16.778 -31.818 1.00 42.69 ? 77  HIS C O   1 
ATOM   4181 C CB  . HIS C 1 75  ? -33.811 -16.062 -29.215 1.00 44.32 ? 77  HIS C CB  1 
ATOM   4182 C CG  . HIS C 1 75  ? -33.046 -14.784 -29.382 1.00 45.28 ? 77  HIS C CG  1 
ATOM   4183 N ND1 . HIS C 1 75  ? -32.929 -14.139 -30.597 1.00 46.68 ? 77  HIS C ND1 1 
ATOM   4184 C CD2 . HIS C 1 75  ? -32.366 -14.026 -28.488 1.00 45.13 ? 77  HIS C CD2 1 
ATOM   4185 C CE1 . HIS C 1 75  ? -32.206 -13.043 -30.445 1.00 46.14 ? 77  HIS C CE1 1 
ATOM   4186 N NE2 . HIS C 1 75  ? -31.850 -12.953 -29.176 1.00 44.97 ? 77  HIS C NE2 1 
ATOM   4187 N N   . MET C 1 76  ? -30.744 -17.272 -30.530 1.00 37.82 ? 78  MET C N   1 
ATOM   4188 C CA  . MET C 1 76  ? -29.738 -17.114 -31.607 1.00 40.54 ? 78  MET C CA  1 
ATOM   4189 C C   . MET C 1 76  ? -28.907 -18.348 -31.950 1.00 40.09 ? 78  MET C C   1 
ATOM   4190 O O   . MET C 1 76  ? -28.004 -18.292 -32.734 1.00 37.34 ? 78  MET C O   1 
ATOM   4191 C CB  . MET C 1 76  ? -28.722 -16.044 -31.214 1.00 38.64 ? 78  MET C CB  1 
ATOM   4192 C CG  . MET C 1 76  ? -29.248 -14.681 -31.292 1.00 41.12 ? 78  MET C CG  1 
ATOM   4193 S SD  . MET C 1 76  ? -28.127 -13.456 -30.805 1.00 43.45 ? 78  MET C SD  1 
ATOM   4194 C CE  . MET C 1 76  ? -27.080 -13.415 -32.203 1.00 31.36 ? 78  MET C CE  1 
ATOM   4195 N N   . LYS C 1 77  ? -29.190 -19.454 -31.315 1.00 43.87 ? 79  LYS C N   1 
ATOM   4196 C CA  . LYS C 1 77  ? -28.382 -20.635 -31.484 1.00 41.16 ? 79  LYS C CA  1 
ATOM   4197 C C   . LYS C 1 77  ? -28.237 -21.123 -32.883 1.00 42.48 ? 79  LYS C C   1 
ATOM   4198 O O   . LYS C 1 77  ? -27.276 -21.743 -33.239 1.00 53.79 ? 79  LYS C O   1 
ATOM   4199 C CB  . LYS C 1 77  ? -28.886 -21.706 -30.564 1.00 41.25 ? 79  LYS C CB  1 
ATOM   4200 C CG  . LYS C 1 77  ? -28.617 -21.267 -29.190 1.00 42.95 ? 79  LYS C CG  1 
ATOM   4201 C CD  . LYS C 1 77  ? -28.309 -22.347 -28.241 1.00 46.09 ? 79  LYS C CD  1 
ATOM   4202 C CE  . LYS C 1 77  ? -27.520 -21.773 -27.110 1.00 49.06 ? 79  LYS C CE  1 
ATOM   4203 N NZ  . LYS C 1 77  ? -27.862 -22.348 -25.813 1.00 57.09 ? 79  LYS C NZ  1 
ATOM   4204 N N   . ARG C 1 78  ? -29.147 -20.801 -33.738 1.00 38.18 ? 80  ARG C N   1 
ATOM   4205 C CA  . ARG C 1 78  ? -28.963 -21.275 -35.064 1.00 39.32 ? 80  ARG C CA  1 
ATOM   4206 C C   . ARG C 1 78  ? -28.029 -20.382 -35.851 1.00 40.42 ? 80  ARG C C   1 
ATOM   4207 O O   . ARG C 1 78  ? -27.899 -20.596 -37.034 1.00 35.17 ? 80  ARG C O   1 
ATOM   4208 C CB  . ARG C 1 78  ? -30.290 -21.354 -35.763 1.00 47.97 ? 80  ARG C CB  1 
ATOM   4209 C CG  . ARG C 1 78  ? -30.867 -20.007 -35.933 1.00 49.16 ? 80  ARG C CG  1 
ATOM   4210 C CD  . ARG C 1 78  ? -31.518 -19.584 -34.673 1.00 53.08 ? 80  ARG C CD  1 
ATOM   4211 N NE  . ARG C 1 78  ? -32.953 -19.719 -34.889 1.00 60.35 ? 80  ARG C NE  1 
ATOM   4212 C CZ  . ARG C 1 78  ? -33.742 -18.791 -35.415 1.00 65.26 ? 80  ARG C CZ  1 
ATOM   4213 N NH1 . ARG C 1 78  ? -33.251 -17.620 -35.793 1.00 61.84 ? 80  ARG C NH1 1 
ATOM   4214 N NH2 . ARG C 1 78  ? -35.038 -19.044 -35.550 1.00 63.23 ? 80  ARG C NH2 1 
ATOM   4215 N N   . HIS C 1 79  ? -27.374 -19.412 -35.199 1.00 35.31 ? 81  HIS C N   1 
ATOM   4216 C CA  . HIS C 1 79  ? -26.490 -18.544 -35.952 1.00 34.60 ? 81  HIS C CA  1 
ATOM   4217 C C   . HIS C 1 79  ? -25.063 -18.732 -35.431 1.00 29.23 ? 81  HIS C C   1 
ATOM   4218 O O   . HIS C 1 79  ? -24.231 -17.921 -35.662 1.00 28.47 ? 81  HIS C O   1 
ATOM   4219 C CB  . HIS C 1 79  ? -26.900 -17.093 -35.800 1.00 34.30 ? 81  HIS C CB  1 
ATOM   4220 C CG  . HIS C 1 79  ? -28.216 -16.770 -36.423 1.00 37.54 ? 81  HIS C CG  1 
ATOM   4221 N ND1 . HIS C 1 79  ? -28.394 -16.715 -37.780 1.00 40.52 ? 81  HIS C ND1 1 
ATOM   4222 C CD2 . HIS C 1 79  ? -29.409 -16.471 -35.880 1.00 46.41 ? 81  HIS C CD2 1 
ATOM   4223 C CE1 . HIS C 1 79  ? -29.646 -16.410 -38.050 1.00 42.41 ? 81  HIS C CE1 1 
ATOM   4224 N NE2 . HIS C 1 79  ? -30.287 -16.268 -36.914 1.00 45.12 ? 81  HIS C NE2 1 
ATOM   4225 N N   . ASP C 1 80  ? -24.836 -19.814 -34.703 1.00 31.04 ? 82  ASP C N   1 
ATOM   4226 C CA  . ASP C 1 80  ? -23.543 -20.104 -34.075 1.00 24.46 ? 82  ASP C CA  1 
ATOM   4227 C C   . ASP C 1 80  ? -22.666 -20.977 -34.945 1.00 22.31 ? 82  ASP C C   1 
ATOM   4228 O O   . ASP C 1 80  ? -22.566 -22.127 -34.749 1.00 21.85 ? 82  ASP C O   1 
ATOM   4229 C CB  . ASP C 1 80  ? -23.694 -20.676 -32.666 1.00 23.22 ? 82  ASP C CB  1 
ATOM   4230 C CG  . ASP C 1 80  ? -22.403 -20.610 -31.847 1.00 24.06 ? 82  ASP C CG  1 
ATOM   4231 O OD1 . ASP C 1 80  ? -21.371 -20.382 -32.437 1.00 20.76 ? 82  ASP C OD1 1 
ATOM   4232 O OD2 . ASP C 1 80  ? -22.470 -20.758 -30.618 1.00 22.24 ? 82  ASP C OD2 1 
ATOM   4233 N N   . PHE C 1 81  ? -22.043 -20.354 -35.908 1.00 18.44 ? 83  PHE C N   1 
ATOM   4234 C CA  . PHE C 1 81  ? -21.168 -21.075 -36.824 1.00 23.49 ? 83  PHE C CA  1 
ATOM   4235 C C   . PHE C 1 81  ? -20.023 -21.745 -36.078 1.00 20.37 ? 83  PHE C C   1 
ATOM   4236 O O   . PHE C 1 81  ? -19.633 -22.876 -36.396 1.00 19.98 ? 83  PHE C O   1 
ATOM   4237 C CB  . PHE C 1 81  ? -20.612 -20.107 -37.875 1.00 19.06 ? 83  PHE C CB  1 
ATOM   4238 C CG  . PHE C 1 81  ? -19.358 -20.593 -38.541 1.00 21.89 ? 83  PHE C CG  1 
ATOM   4239 C CD1 . PHE C 1 81  ? -18.105 -20.308 -38.019 1.00 19.71 ? 83  PHE C CD1 1 
ATOM   4240 C CD2 . PHE C 1 81  ? -19.439 -21.373 -39.683 1.00 21.61 ? 83  PHE C CD2 1 
ATOM   4241 C CE1 . PHE C 1 81  ? -16.960 -20.783 -38.634 1.00 19.95 ? 83  PHE C CE1 1 
ATOM   4242 C CE2 . PHE C 1 81  ? -18.300 -21.846 -40.302 1.00 24.52 ? 83  PHE C CE2 1 
ATOM   4243 C CZ  . PHE C 1 81  ? -17.059 -21.558 -39.772 1.00 21.79 ? 83  PHE C CZ  1 
ATOM   4244 N N   . PHE C 1 82  ? -19.451 -21.042 -35.104 1.00 19.39 ? 84  PHE C N   1 
ATOM   4245 C CA  . PHE C 1 82  ? -18.223 -21.500 -34.472 1.00 16.90 ? 84  PHE C CA  1 
ATOM   4246 C C   . PHE C 1 82  ? -18.423 -22.838 -33.769 1.00 15.96 ? 84  PHE C C   1 
ATOM   4247 O O   . PHE C 1 82  ? -17.614 -23.760 -33.923 1.00 19.21 ? 84  PHE C O   1 
ATOM   4248 C CB  . PHE C 1 82  ? -17.730 -20.442 -33.488 1.00 15.40 ? 84  PHE C CB  1 
ATOM   4249 C CG  . PHE C 1 82  ? -17.548 -19.079 -34.109 1.00 16.44 ? 84  PHE C CG  1 
ATOM   4250 C CD1 . PHE C 1 82  ? -16.429 -18.797 -34.877 1.00 17.70 ? 84  PHE C CD1 1 
ATOM   4251 C CD2 . PHE C 1 82  ? -18.476 -18.077 -33.889 1.00 17.08 ? 84  PHE C CD2 1 
ATOM   4252 C CE1 . PHE C 1 82  ? -16.255 -17.553 -35.448 1.00 20.06 ? 84  PHE C CE1 1 
ATOM   4253 C CE2 . PHE C 1 82  ? -18.309 -16.817 -34.447 1.00 19.53 ? 84  PHE C CE2 1 
ATOM   4254 C CZ  . PHE C 1 82  ? -17.198 -16.557 -35.237 1.00 18.44 ? 84  PHE C CZ  1 
ATOM   4255 N N   . LYS C 1 83  ? -19.488 -22.962 -32.977 1.00 17.10 ? 85  LYS C N   1 
ATOM   4256 C CA  . LYS C 1 83  ? -19.720 -24.232 -32.285 1.00 18.39 ? 85  LYS C CA  1 
ATOM   4257 C C   . LYS C 1 83  ? -20.175 -25.322 -33.251 1.00 20.20 ? 85  LYS C C   1 
ATOM   4258 O O   . LYS C 1 83  ? -19.828 -26.497 -33.080 1.00 16.39 ? 85  LYS C O   1 
ATOM   4259 C CB  . LYS C 1 83  ? -20.750 -24.048 -31.177 1.00 19.39 ? 85  LYS C CB  1 
ATOM   4260 C CG  . LYS C 1 83  ? -20.297 -23.152 -30.026 1.00 17.50 ? 85  LYS C CG  1 
ATOM   4261 C CD  . LYS C 1 83  ? -21.322 -23.210 -28.903 1.00 16.30 ? 85  LYS C CD  1 
ATOM   4262 C CE  . LYS C 1 83  ? -21.046 -22.157 -27.820 1.00 21.70 ? 85  LYS C CE  1 
ATOM   4263 N NZ  . LYS C 1 83  ? -20.957 -20.757 -28.378 1.00 16.31 ? 85  LYS C NZ  1 
ATOM   4264 N N   . SER C 1 84  ? -20.964 -24.949 -34.257 1.00 20.59 ? 86  SER C N   1 
ATOM   4265 C CA  . SER C 1 84  ? -21.508 -25.914 -35.208 1.00 22.90 ? 86  SER C CA  1 
ATOM   4266 C C   . SER C 1 84  ? -20.419 -26.617 -36.017 1.00 24.53 ? 86  SER C C   1 
ATOM   4267 O O   . SER C 1 84  ? -20.627 -27.748 -36.484 1.00 23.59 ? 86  SER C O   1 
ATOM   4268 C CB  . SER C 1 84  ? -22.503 -25.192 -36.118 1.00 24.68 ? 86  SER C CB  1 
ATOM   4269 O OG  . SER C 1 84  ? -21.862 -24.701 -37.288 1.00 27.76 ? 86  SER C OG  1 
ATOM   4270 N N   . ALA C 1 85  ? -19.258 -25.976 -36.179 1.00 17.74 ? 87  ALA C N   1 
ATOM   4271 C CA  . ALA C 1 85  ? -18.125 -26.564 -36.878 1.00 18.74 ? 87  ALA C CA  1 
ATOM   4272 C C   . ALA C 1 85  ? -17.375 -27.603 -36.044 1.00 18.82 ? 87  ALA C C   1 
ATOM   4273 O O   . ALA C 1 85  ? -16.540 -28.325 -36.600 1.00 18.94 ? 87  ALA C O   1 
ATOM   4274 C CB  . ALA C 1 85  ? -17.158 -25.460 -37.313 1.00 19.61 ? 87  ALA C CB  1 
ATOM   4275 N N   . MET C 1 86  ? -17.632 -27.665 -34.736 1.00 17.84 ? 88  MET C N   1 
ATOM   4276 C CA  . MET C 1 86  ? -17.002 -28.623 -33.825 1.00 19.11 ? 88  MET C CA  1 
ATOM   4277 C C   . MET C 1 86  ? -17.608 -30.024 -33.955 1.00 21.80 ? 88  MET C C   1 
ATOM   4278 O O   . MET C 1 86  ? -18.779 -30.172 -34.307 1.00 22.26 ? 88  MET C O   1 
ATOM   4279 C CB  . MET C 1 86  ? -17.140 -28.126 -32.384 1.00 19.84 ? 88  MET C CB  1 
ATOM   4280 C CG  . MET C 1 86  ? -16.247 -26.953 -31.936 1.00 19.94 ? 88  MET C CG  1 
ATOM   4281 S SD  . MET C 1 86  ? -14.633 -26.863 -32.736 1.00 14.88 ? 88  MET C SD  1 
ATOM   4282 C CE  . MET C 1 86  ? -14.318 -25.077 -32.824 1.00 14.71 ? 88  MET C CE  1 
ATOM   4283 N N   . PRO C 1 87  ? -16.829 -31.079 -33.648 1.00 20.35 ? 89  PRO C N   1 
ATOM   4284 C CA  . PRO C 1 87  ? -15.445 -31.059 -33.138 1.00 18.08 ? 89  PRO C CA  1 
ATOM   4285 C C   . PRO C 1 87  ? -14.370 -30.917 -34.213 1.00 21.35 ? 89  PRO C C   1 
ATOM   4286 O O   . PRO C 1 87  ? -13.205 -30.682 -33.871 1.00 20.00 ? 89  PRO C O   1 
ATOM   4287 C CB  . PRO C 1 87  ? -15.312 -32.433 -32.456 1.00 21.82 ? 89  PRO C CB  1 
ATOM   4288 C CG  . PRO C 1 87  ? -16.206 -33.320 -33.278 1.00 20.55 ? 89  PRO C CG  1 
ATOM   4289 C CD  . PRO C 1 87  ? -17.393 -32.446 -33.651 1.00 20.84 ? 89  PRO C CD  1 
ATOM   4290 N N   . GLU C 1 88  ? -14.732 -31.089 -35.490 1.00 19.04 ? 90  GLU C N   1 
ATOM   4291 C CA  . GLU C 1 88  ? -13.710 -31.071 -36.531 1.00 17.89 ? 90  GLU C CA  1 
ATOM   4292 C C   . GLU C 1 88  ? -13.036 -29.708 -36.596 1.00 19.78 ? 90  GLU C C   1 
ATOM   4293 O O   . GLU C 1 88  ? -11.824 -29.616 -36.817 1.00 16.96 ? 90  GLU C O   1 
ATOM   4294 C CB  . GLU C 1 88  ? -14.311 -31.462 -37.886 1.00 19.77 ? 90  GLU C CB  1 
ATOM   4295 C CG  . GLU C 1 88  ? -15.085 -32.782 -37.841 1.00 26.92 ? 90  GLU C CG  1 
ATOM   4296 C CD  . GLU C 1 88  ? -16.583 -32.595 -37.625 1.00 35.79 ? 90  GLU C CD  1 
ATOM   4297 O OE1 . GLU C 1 88  ? -17.361 -33.210 -38.391 1.00 44.31 ? 90  GLU C OE1 1 
ATOM   4298 O OE2 . GLU C 1 88  ? -16.978 -31.795 -36.743 1.00 26.58 ? 90  GLU C OE2 1 
ATOM   4299 N N   . GLY C 1 89  ? -13.802 -28.639 -36.398 1.00 16.82 ? 91  GLY C N   1 
ATOM   4300 C CA  . GLY C 1 89  ? -13.225 -27.335 -36.152 1.00 17.26 ? 91  GLY C CA  1 
ATOM   4301 C C   . GLY C 1 89  ? -13.274 -26.407 -37.354 1.00 18.82 ? 91  GLY C C   1 
ATOM   4302 O O   . GLY C 1 89  ? -13.875 -26.697 -38.394 1.00 17.24 ? 91  GLY C O   1 
ATOM   4303 N N   . TYR C 1 90  ? -12.610 -25.265 -37.194 1.00 14.31 ? 92  TYR C N   1 
ATOM   4304 C CA  . TYR C 1 90  ? -12.566 -24.260 -38.251 1.00 17.97 ? 92  TYR C CA  1 
ATOM   4305 C C   . TYR C 1 90  ? -11.183 -23.639 -38.361 1.00 15.96 ? 92  TYR C C   1 
ATOM   4306 O O   . TYR C 1 90  ? -10.395 -23.637 -37.408 1.00 16.10 ? 92  TYR C O   1 
ATOM   4307 C CB  . TYR C 1 90  ? -13.638 -23.170 -38.029 1.00 14.23 ? 92  TYR C CB  1 
ATOM   4308 C CG  . TYR C 1 90  ? -13.562 -22.419 -36.722 1.00 14.92 ? 92  TYR C CG  1 
ATOM   4309 C CD1 . TYR C 1 90  ? -12.633 -21.402 -36.516 1.00 13.30 ? 92  TYR C CD1 1 
ATOM   4310 C CD2 . TYR C 1 90  ? -14.449 -22.710 -35.698 1.00 15.54 ? 92  TYR C CD2 1 
ATOM   4311 C CE1 . TYR C 1 90  ? -12.584 -20.719 -35.319 1.00 13.09 ? 92  TYR C CE1 1 
ATOM   4312 C CE2 . TYR C 1 90  ? -14.402 -22.032 -34.503 1.00 15.49 ? 92  TYR C CE2 1 
ATOM   4313 C CZ  . TYR C 1 90  ? -13.470 -21.035 -34.322 1.00 13.09 ? 92  TYR C CZ  1 
ATOM   4314 O OH  . TYR C 1 90  ? -13.460 -20.361 -33.119 1.00 14.44 ? 92  TYR C OH  1 
ATOM   4315 N N   . VAL C 1 91  ? -10.887 -23.159 -39.569 1.00 15.91 ? 93  VAL C N   1 
ATOM   4316 C CA  . VAL C 1 91  ? -9.698  -22.371 -39.855 1.00 16.76 ? 93  VAL C CA  1 
ATOM   4317 C C   . VAL C 1 91  ? -10.053 -20.908 -39.623 1.00 17.07 ? 93  VAL C C   1 
ATOM   4318 O O   . VAL C 1 91  ? -11.088 -20.434 -40.105 1.00 17.54 ? 93  VAL C O   1 
ATOM   4319 C CB  . VAL C 1 91  ? -9.231  -22.588 -41.309 1.00 17.76 ? 93  VAL C CB  1 
ATOM   4320 C CG1 . VAL C 1 91  ? -8.062  -21.673 -41.639 1.00 18.02 ? 93  VAL C CG1 1 
ATOM   4321 C CG2 . VAL C 1 91  ? -8.885  -24.037 -41.566 1.00 19.05 ? 93  VAL C CG2 1 
ATOM   4322 N N   . GLN C 1 92  ? -9.210  -20.193 -38.881 1.00 14.57 ? 94  GLN C N   1 
ATOM   4323 C CA  . GLN C 1 92  ? -9.362  -18.753 -38.686 1.00 16.59 ? 94  GLN C CA  1 
ATOM   4324 C C   . GLN C 1 92  ? -8.149  -18.041 -39.261 1.00 15.21 ? 94  GLN C C   1 
ATOM   4325 O O   . GLN C 1 92  ? -7.017  -18.284 -38.821 1.00 14.29 ? 94  GLN C O   1 
ATOM   4326 C CB  . GLN C 1 92  ? -9.533  -18.404 -37.202 1.00 14.68 ? 94  GLN C CB  1 
ATOM   4327 C CG  . GLN C 1 92  ? -9.842  -16.919 -36.975 1.00 13.23 ? 94  GLN C CG  1 
ATOM   4328 C CD  . GLN C 1 92  ? -10.472 -16.641 -35.638 1.00 13.35 ? 94  GLN C CD  1 
ATOM   4329 O OE1 . GLN C 1 92  ? -11.580 -17.103 -35.366 1.00 15.33 ? 94  GLN C OE1 1 
ATOM   4330 N NE2 . GLN C 1 92  ? -9.806  -15.839 -34.816 1.00 14.03 ? 94  GLN C NE2 1 
ATOM   4331 N N   . GLU C 1 93  ? -8.383  -17.144 -40.226 1.00 14.20 ? 95  GLU C N   1 
ATOM   4332 C CA  . GLU C 1 93  ? -7.304  -16.427 -40.888 1.00 14.61 ? 95  GLU C CA  1 
ATOM   4333 C C   . GLU C 1 93  ? -7.493  -14.928 -40.704 1.00 15.93 ? 95  GLU C C   1 
ATOM   4334 O O   . GLU C 1 93  ? -8.615  -14.421 -40.811 1.00 16.18 ? 95  GLU C O   1 
ATOM   4335 C CB  . GLU C 1 93  ? -7.268  -16.738 -42.391 1.00 18.13 ? 95  GLU C CB  1 
ATOM   4336 C CG  . GLU C 1 93  ? -6.757  -18.142 -42.692 1.00 19.03 ? 95  GLU C CG  1 
ATOM   4337 C CD  . GLU C 1 93  ? -6.911  -18.515 -44.162 1.00 29.13 ? 95  GLU C CD  1 
ATOM   4338 O OE1 . GLU C 1 93  ? -8.049  -18.566 -44.680 1.00 27.90 ? 95  GLU C OE1 1 
ATOM   4339 O OE2 . GLU C 1 93  ? -5.870  -18.789 -44.790 1.00 26.71 ? 95  GLU C OE2 1 
ATOM   4340 N N   . ARG C 1 94  ? -6.400  -14.209 -40.455 1.00 10.61 ? 96  ARG C N   1 
ATOM   4341 C CA  . ARG C 1 94  ? -6.503  -12.763 -40.376 1.00 12.86 ? 96  ARG C CA  1 
ATOM   4342 C C   . ARG C 1 94  ? -5.298  -12.093 -41.019 1.00 12.49 ? 96  ARG C C   1 
ATOM   4343 O O   . ARG C 1 94  ? -4.192  -12.640 -41.047 1.00 12.68 ? 96  ARG C O   1 
ATOM   4344 C CB  . ARG C 1 94  ? -6.619  -12.288 -38.916 1.00 10.45 ? 96  ARG C CB  1 
ATOM   4345 C CG  . ARG C 1 94  ? -7.930  -12.630 -38.217 1.00 8.93  ? 96  ARG C CG  1 
ATOM   4346 C CD  . ARG C 1 94  ? -8.281  -11.536 -37.208 1.00 10.76 ? 96  ARG C CD  1 
ATOM   4347 N NE  . ARG C 1 94  ? -9.421  -11.892 -36.371 1.00 10.19 ? 96  ARG C NE  1 
ATOM   4348 C CZ  . ARG C 1 94  ? -9.330  -12.466 -35.176 1.00 13.19 ? 96  ARG C CZ  1 
ATOM   4349 N NH1 . ARG C 1 94  ? -8.170  -12.880 -34.693 1.00 11.29 ? 96  ARG C NH1 1 
ATOM   4350 N NH2 . ARG C 1 94  ? -10.427 -12.598 -34.439 1.00 10.82 ? 96  ARG C NH2 1 
ATOM   4351 N N   . THR C 1 95  ? -5.525  -10.884 -41.524 1.00 12.06 ? 97  THR C N   1 
ATOM   4352 C CA  . THR C 1 95  ? -4.471  -9.898  -41.698 1.00 13.72 ? 97  THR C CA  1 
ATOM   4353 C C   . THR C 1 95  ? -4.772  -8.726  -40.779 1.00 13.37 ? 97  THR C C   1 
ATOM   4354 O O   . THR C 1 95  ? -5.922  -8.279  -40.702 1.00 13.55 ? 97  THR C O   1 
ATOM   4355 C CB  . THR C 1 95  ? -4.365  -9.418  -43.153 1.00 17.10 ? 97  THR C CB  1 
ATOM   4356 O OG1 . THR C 1 95  ? -4.101  -10.539 -44.002 1.00 15.90 ? 97  THR C OG1 1 
ATOM   4357 C CG2 . THR C 1 95  ? -3.253  -8.408  -43.285 1.00 15.19 ? 97  THR C CG2 1 
ATOM   4358 N N   . ILE C 1 96  ? -3.751  -8.262  -40.061 1.00 12.07 ? 98  ILE C N   1 
ATOM   4359 C CA  . ILE C 1 96  ? -3.867  -7.156  -39.124 1.00 11.18 ? 98  ILE C CA  1 
ATOM   4360 C C   . ILE C 1 96  ? -2.844  -6.110  -39.537 1.00 14.68 ? 98  ILE C C   1 
ATOM   4361 O O   . ILE C 1 96  ? -1.635  -6.354  -39.454 1.00 14.25 ? 98  ILE C O   1 
ATOM   4362 C CB  . ILE C 1 96  ? -3.628  -7.603  -37.668 1.00 12.63 ? 98  ILE C CB  1 
ATOM   4363 C CG1 . ILE C 1 96  ? -4.553  -8.765  -37.300 1.00 12.40 ? 98  ILE C CG1 1 
ATOM   4364 C CG2 . ILE C 1 96  ? -3.832  -6.415  -36.714 1.00 11.23 ? 98  ILE C CG2 1 
ATOM   4365 C CD1 . ILE C 1 96  ? -4.238  -9.453  -35.921 1.00 9.54  ? 98  ILE C CD1 1 
ATOM   4366 N N   . PHE C 1 97  ? -3.315  -4.938  -39.963 1.00 12.52 ? 99  PHE C N   1 
ATOM   4367 C CA  . PHE C 1 97  ? -2.438  -3.872  -40.423 1.00 15.13 ? 99  PHE C CA  1 
ATOM   4368 C C   . PHE C 1 97  ? -2.246  -2.912  -39.259 1.00 16.46 ? 99  PHE C C   1 
ATOM   4369 O O   . PHE C 1 97  ? -3.225  -2.345  -38.767 1.00 13.34 ? 99  PHE C O   1 
ATOM   4370 C CB  . PHE C 1 97  ? -3.050  -3.114  -41.606 1.00 15.48 ? 99  PHE C CB  1 
ATOM   4371 C CG  . PHE C 1 97  ? -3.191  -3.918  -42.871 1.00 15.21 ? 99  PHE C CG  1 
ATOM   4372 C CD1 . PHE C 1 97  ? -2.123  -4.099  -43.724 1.00 19.42 ? 99  PHE C CD1 1 
ATOM   4373 C CD2 . PHE C 1 97  ? -4.423  -4.459  -43.226 1.00 15.58 ? 99  PHE C CD2 1 
ATOM   4374 C CE1 . PHE C 1 97  ? -2.265  -4.836  -44.902 1.00 17.39 ? 99  PHE C CE1 1 
ATOM   4375 C CE2 . PHE C 1 97  ? -4.578  -5.178  -44.406 1.00 15.43 ? 99  PHE C CE2 1 
ATOM   4376 C CZ  . PHE C 1 97  ? -3.491  -5.367  -45.246 1.00 14.17 ? 99  PHE C CZ  1 
ATOM   4377 N N   . PHE C 1 98  ? -1.007  -2.726  -38.821 1.00 14.48 ? 100 PHE C N   1 
ATOM   4378 C CA  . PHE C 1 98  ? -0.702  -1.693  -37.838 1.00 16.80 ? 100 PHE C CA  1 
ATOM   4379 C C   . PHE C 1 98  ? -0.372  -0.409  -38.588 1.00 19.02 ? 100 PHE C C   1 
ATOM   4380 O O   . PHE C 1 98  ? 0.568   -0.373  -39.387 1.00 17.32 ? 100 PHE C O   1 
ATOM   4381 C CB  . PHE C 1 98  ? 0.437   -2.124  -36.912 1.00 15.18 ? 100 PHE C CB  1 
ATOM   4382 C CG  . PHE C 1 98  ? 0.081   -3.312  -36.067 1.00 15.56 ? 100 PHE C CG  1 
ATOM   4383 C CD1 . PHE C 1 98  ? -0.526  -3.140  -34.834 1.00 13.28 ? 100 PHE C CD1 1 
ATOM   4384 C CD2 . PHE C 1 98  ? 0.295   -4.605  -36.540 1.00 15.68 ? 100 PHE C CD2 1 
ATOM   4385 C CE1 . PHE C 1 98  ? -0.896  -4.234  -34.067 1.00 14.02 ? 100 PHE C CE1 1 
ATOM   4386 C CE2 . PHE C 1 98  ? -0.066  -5.704  -35.789 1.00 11.55 ? 100 PHE C CE2 1 
ATOM   4387 C CZ  . PHE C 1 98  ? -0.659  -5.531  -34.549 1.00 10.86 ? 100 PHE C CZ  1 
ATOM   4388 N N   . LYS C 1 99  ? -1.172  0.622   -38.351 1.00 17.69 ? 101 LYS C N   1 
ATOM   4389 C CA  . LYS C 1 99  ? -1.058  1.868   -39.090 1.00 19.83 ? 101 LYS C CA  1 
ATOM   4390 C C   . LYS C 1 99  ? 0.344   2.431   -38.939 1.00 17.01 ? 101 LYS C C   1 
ATOM   4391 O O   . LYS C 1 99  ? 0.884   2.490   -37.826 1.00 16.00 ? 101 LYS C O   1 
ATOM   4392 C CB  . LYS C 1 99  ? -2.077  2.880   -38.570 1.00 20.01 ? 101 LYS C CB  1 
ATOM   4393 C CG  . LYS C 1 99  ? -1.992  4.264   -39.250 1.00 22.43 ? 101 LYS C CG  1 
ATOM   4394 C CD  . LYS C 1 99  ? -3.383  4.830   -39.531 1.00 32.01 ? 101 LYS C CD  1 
ATOM   4395 C CE  . LYS C 1 99  ? -3.339  6.079   -40.411 1.00 33.71 ? 101 LYS C CE  1 
ATOM   4396 N NZ  . LYS C 1 99  ? -2.486  5.880   -41.626 1.00 40.06 ? 101 LYS C NZ  1 
ATOM   4397 N N   . ASP C 1 100 ? 0.936   2.818   -40.070 1.00 17.45 ? 102 ASP C N   1 
ATOM   4398 C CA  . ASP C 1 100 ? 2.292   3.353   -40.149 1.00 19.92 ? 102 ASP C CA  1 
ATOM   4399 C C   . ASP C 1 100 ? 3.341   2.365   -39.649 1.00 17.39 ? 102 ASP C C   1 
ATOM   4400 O O   . ASP C 1 100 ? 4.443   2.765   -39.261 1.00 19.25 ? 102 ASP C O   1 
ATOM   4401 C CB  . ASP C 1 100 ? 2.409   4.685   -39.400 1.00 23.08 ? 102 ASP C CB  1 
ATOM   4402 C CG  . ASP C 1 100 ? 1.491   5.752   -39.983 1.00 28.53 ? 102 ASP C CG  1 
ATOM   4403 O OD1 . ASP C 1 100 ? 0.898   6.531   -39.206 1.00 32.07 ? 102 ASP C OD1 1 
ATOM   4404 O OD2 . ASP C 1 100 ? 1.316   5.751   -41.221 1.00 24.37 ? 102 ASP C OD2 1 
ATOM   4405 N N   . ASP C 1 101 ? 3.032   1.075   -39.670 1.00 18.37 ? 103 ASP C N   1 
ATOM   4406 C CA  . ASP C 1 101 ? 3.980   0.049   -39.243 1.00 17.68 ? 103 ASP C CA  1 
ATOM   4407 C C   . ASP C 1 101 ? 3.677   -1.214  -40.044 1.00 17.10 ? 103 ASP C C   1 
ATOM   4408 O O   . ASP C 1 101 ? 3.003   -1.157  -41.076 1.00 16.77 ? 103 ASP C O   1 
ATOM   4409 C CB  . ASP C 1 101 ? 3.902   -0.172  -37.723 1.00 15.62 ? 103 ASP C CB  1 
ATOM   4410 C CG  . ASP C 1 101 ? 5.250   -0.552  -37.113 1.00 18.38 ? 103 ASP C CG  1 
ATOM   4411 O OD1 . ASP C 1 101 ? 6.059   -1.203  -37.810 1.00 17.87 ? 103 ASP C OD1 1 
ATOM   4412 O OD2 . ASP C 1 101 ? 5.497   -0.224  -35.935 1.00 16.65 ? 103 ASP C OD2 1 
ATOM   4413 N N   . GLY C 1 102 ? 4.159   -2.366  -39.570 1.00 17.02 ? 104 GLY C N   1 
ATOM   4414 C CA  . GLY C 1 102 ? 3.989   -3.606  -40.304 1.00 14.08 ? 104 GLY C CA  1 
ATOM   4415 C C   . GLY C 1 102 ? 2.625   -4.250  -40.117 1.00 17.05 ? 104 GLY C C   1 
ATOM   4416 O O   . GLY C 1 102 ? 1.674   -3.654  -39.606 1.00 16.59 ? 104 GLY C O   1 
ATOM   4417 N N   . ASN C 1 103 ? 2.539   -5.515  -40.539 1.00 13.44 ? 105 ASN C N   1 
ATOM   4418 C CA  . ASN C 1 103 ? 1.290   -6.262  -40.492 1.00 13.27 ? 105 ASN C CA  1 
ATOM   4419 C C   . ASN C 1 103 ? 1.523   -7.697  -40.027 1.00 14.04 ? 105 ASN C C   1 
ATOM   4420 O O   . ASN C 1 103 ? 2.581   -8.281  -40.278 1.00 15.19 ? 105 ASN C O   1 
ATOM   4421 C CB  . ASN C 1 103 ? 0.595   -6.280  -41.855 1.00 13.58 ? 105 ASN C CB  1 
ATOM   4422 C CG  . ASN C 1 103 ? 1.413   -7.010  -42.921 1.00 19.27 ? 105 ASN C CG  1 
ATOM   4423 O OD1 . ASN C 1 103 ? 1.275   -8.226  -43.109 1.00 16.43 ? 105 ASN C OD1 1 
ATOM   4424 N ND2 . ASN C 1 103 ? 2.230   -6.253  -43.657 1.00 17.42 ? 105 ASN C ND2 1 
ATOM   4425 N N   . TYR C 1 104 ? 0.529   -8.252  -39.325 1.00 12.82 ? 106 TYR C N   1 
ATOM   4426 C CA  . TYR C 1 104 ? 0.488   -9.681  -39.012 1.00 10.04 ? 106 TYR C CA  1 
ATOM   4427 C C   . TYR C 1 104 ? -0.406  -10.385 -40.019 1.00 15.42 ? 106 TYR C C   1 
ATOM   4428 O O   . TYR C 1 104 ? -1.479  -9.882  -40.356 1.00 13.38 ? 106 TYR C O   1 
ATOM   4429 C CB  . TYR C 1 104 ? -0.091  -9.985  -37.619 1.00 9.84  ? 106 TYR C CB  1 
ATOM   4430 C CG  . TYR C 1 104 ? 0.635   -9.456  -36.401 1.00 10.54 ? 106 TYR C CG  1 
ATOM   4431 C CD1 . TYR C 1 104 ? 1.962   -9.083  -36.446 1.00 10.02 ? 106 TYR C CD1 1 
ATOM   4432 C CD2 . TYR C 1 104 ? -0.041  -9.345  -35.181 1.00 12.46 ? 106 TYR C CD2 1 
ATOM   4433 C CE1 . TYR C 1 104 ? 2.604   -8.598  -35.311 1.00 10.40 ? 106 TYR C CE1 1 
ATOM   4434 C CE2 . TYR C 1 104 ? 0.586   -8.879  -34.052 1.00 11.00 ? 106 TYR C CE2 1 
ATOM   4435 C CZ  . TYR C 1 104 ? 1.911   -8.500  -34.118 1.00 11.55 ? 106 TYR C CZ  1 
ATOM   4436 O OH  . TYR C 1 104 ? 2.533   -8.025  -32.979 1.00 12.02 ? 106 TYR C OH  1 
ATOM   4437 N N   . LYS C 1 105 ? 0.023   -11.562 -40.483 1.00 13.07 ? 107 LYS C N   1 
ATOM   4438 C CA  . LYS C 1 105 ? -0.865  -12.531 -41.107 1.00 13.98 ? 107 LYS C CA  1 
ATOM   4439 C C   . LYS C 1 105 ? -0.910  -13.735 -40.181 1.00 14.27 ? 107 LYS C C   1 
ATOM   4440 O O   . LYS C 1 105 ? 0.136   -14.168 -39.695 1.00 14.05 ? 107 LYS C O   1 
ATOM   4441 C CB  . LYS C 1 105 ? -0.380  -12.943 -42.505 1.00 13.91 ? 107 LYS C CB  1 
ATOM   4442 C CG  . LYS C 1 105 ? -0.384  -11.808 -43.540 1.00 21.56 ? 107 LYS C CG  1 
ATOM   4443 C CD  . LYS C 1 105 ? 0.249   -12.263 -44.868 1.00 23.50 ? 107 LYS C CD  1 
ATOM   4444 C CE  . LYS C 1 105 ? -0.760  -13.032 -45.724 1.00 27.44 ? 107 LYS C CE  1 
ATOM   4445 N NZ  . LYS C 1 105 ? -0.176  -13.313 -47.081 1.00 32.10 ? 107 LYS C NZ  1 
ATOM   4446 N N   . THR C 1 106 ? -2.110  -14.241 -39.901 1.00 13.26 ? 108 THR C N   1 
ATOM   4447 C CA  . THR C 1 106 ? -2.263  -15.358 -38.974 1.00 12.57 ? 108 THR C CA  1 
ATOM   4448 C C   . THR C 1 106 ? -3.152  -16.429 -39.579 1.00 14.56 ? 108 THR C C   1 
ATOM   4449 O O   . THR C 1 106 ? -4.152  -16.127 -40.232 1.00 13.31 ? 108 THR C O   1 
ATOM   4450 C CB  . THR C 1 106 ? -2.851  -14.907 -37.612 1.00 13.91 ? 108 THR C CB  1 
ATOM   4451 O OG1 . THR C 1 106 ? -4.196  -14.430 -37.782 1.00 11.47 ? 108 THR C OG1 1 
ATOM   4452 C CG2 . THR C 1 106 ? -2.018  -13.796 -36.999 1.00 11.62 ? 108 THR C CG2 1 
ATOM   4453 N N   . ARG C 1 107 ? -2.766  -17.688 -39.380 1.00 11.88 ? 109 ARG C N   1 
ATOM   4454 C CA  . ARG C 1 107 ? -3.592  -18.826 -39.736 1.00 14.29 ? 109 ARG C CA  1 
ATOM   4455 C C   . ARG C 1 107 ? -3.693  -19.681 -38.490 1.00 15.24 ? 109 ARG C C   1 
ATOM   4456 O O   . ARG C 1 107 ? -2.663  -20.028 -37.895 1.00 14.22 ? 109 ARG C O   1 
ATOM   4457 C CB  . ARG C 1 107 ? -2.988  -19.653 -40.883 1.00 14.73 ? 109 ARG C CB  1 
ATOM   4458 C CG  . ARG C 1 107 ? -4.002  -20.521 -41.584 1.00 15.91 ? 109 ARG C CG  1 
ATOM   4459 C CD  . ARG C 1 107 ? -3.348  -21.551 -42.491 1.00 23.98 ? 109 ARG C CD  1 
ATOM   4460 N NE  . ARG C 1 107 ? -4.324  -22.550 -42.912 1.00 23.02 ? 109 ARG C NE  1 
ATOM   4461 C CZ  . ARG C 1 107 ? -4.515  -23.723 -42.324 1.00 26.88 ? 109 ARG C CZ  1 
ATOM   4462 N NH1 . ARG C 1 107 ? -3.787  -24.106 -41.289 1.00 24.85 ? 109 ARG C NH1 1 
ATOM   4463 N NH2 . ARG C 1 107 ? -5.472  -24.526 -42.782 1.00 29.15 ? 109 ARG C NH2 1 
ATOM   4464 N N   . ALA C 1 108 ? -4.916  -19.995 -38.084 1.00 12.05 ? 110 ALA C N   1 
ATOM   4465 C CA  . ALA C 1 108 ? -5.134  -20.819 -36.911 1.00 13.18 ? 110 ALA C CA  1 
ATOM   4466 C C   . ALA C 1 108 ? -6.129  -21.921 -37.241 1.00 14.82 ? 110 ALA C C   1 
ATOM   4467 O O   . ALA C 1 108 ? -6.984  -21.761 -38.110 1.00 14.35 ? 110 ALA C O   1 
ATOM   4468 C CB  . ALA C 1 108 ? -5.653  -19.991 -35.728 1.00 12.20 ? 110 ALA C CB  1 
ATOM   4469 N N   . GLU C 1 109 ? -6.012  -23.045 -36.540 1.00 14.16 ? 111 GLU C N   1 
ATOM   4470 C CA  . GLU C 1 109 ? -7.048  -24.070 -36.558 1.00 14.69 ? 111 GLU C CA  1 
ATOM   4471 C C   . GLU C 1 109 ? -7.592  -24.208 -35.149 1.00 15.22 ? 111 GLU C C   1 
ATOM   4472 O O   . GLU C 1 109 ? -6.821  -24.333 -34.194 1.00 15.24 ? 111 GLU C O   1 
ATOM   4473 C CB  . GLU C 1 109 ? -6.510  -25.415 -37.070 1.00 17.25 ? 111 GLU C CB  1 
ATOM   4474 C CG  . GLU C 1 109 ? -6.115  -25.354 -38.533 1.00 17.40 ? 111 GLU C CG  1 
ATOM   4475 C CD  . GLU C 1 109 ? -5.741  -26.708 -39.127 1.00 25.37 ? 111 GLU C CD  1 
ATOM   4476 O OE1 . GLU C 1 109 ? -5.902  -27.747 -38.450 1.00 22.15 ? 111 GLU C OE1 1 
ATOM   4477 O OE2 . GLU C 1 109 ? -5.245  -26.720 -40.273 1.00 27.75 ? 111 GLU C OE2 1 
ATOM   4478 N N   . VAL C 1 110 ? -8.914  -24.154 -35.016 1.00 13.50 ? 112 VAL C N   1 
ATOM   4479 C CA  . VAL C 1 110 ? -9.580  -24.262 -33.726 1.00 13.93 ? 112 VAL C CA  1 
ATOM   4480 C C   . VAL C 1 110 ? -10.408 -25.534 -33.759 1.00 13.98 ? 112 VAL C C   1 
ATOM   4481 O O   . VAL C 1 110 ? -11.294 -25.679 -34.601 1.00 13.24 ? 112 VAL C O   1 
ATOM   4482 C CB  . VAL C 1 110 ? -10.451 -23.031 -33.431 1.00 13.10 ? 112 VAL C CB  1 
ATOM   4483 C CG1 . VAL C 1 110 ? -11.058 -23.111 -32.028 1.00 13.67 ? 112 VAL C CG1 1 
ATOM   4484 C CG2 . VAL C 1 110 ? -9.617  -21.762 -33.585 1.00 14.42 ? 112 VAL C CG2 1 
ATOM   4485 N N   . LYS C 1 111 ? -10.107 -26.467 -32.873 1.00 11.35 ? 113 LYS C N   1 
ATOM   4486 C CA  . LYS C 1 111 ? -10.779 -27.758 -32.932 1.00 14.20 ? 113 LYS C CA  1 
ATOM   4487 C C   . LYS C 1 111 ? -10.603 -28.469 -31.606 1.00 14.08 ? 113 LYS C C   1 
ATOM   4488 O O   . LYS C 1 111 ? -9.811  -28.061 -30.754 1.00 14.39 ? 113 LYS C O   1 
ATOM   4489 C CB  . LYS C 1 111 ? -10.246 -28.637 -34.072 1.00 15.50 ? 113 LYS C CB  1 
ATOM   4490 C CG  . LYS C 1 111 ? -8.810  -29.149 -33.851 1.00 19.07 ? 113 LYS C CG  1 
ATOM   4491 C CD  . LYS C 1 111 ? -8.299  -29.729 -35.156 1.00 20.60 ? 113 LYS C CD  1 
ATOM   4492 C CE  . LYS C 1 111 ? -7.217  -28.882 -35.748 1.00 22.93 ? 113 LYS C CE  1 
ATOM   4493 N NZ  . LYS C 1 111 ? -6.502  -29.632 -36.820 1.00 26.16 ? 113 LYS C NZ  1 
ATOM   4494 N N   . PHE C 1 112 ? -11.373 -29.535 -31.433 1.00 14.64 ? 114 PHE C N   1 
ATOM   4495 C CA  . PHE C 1 112 ? -11.248 -30.341 -30.233 1.00 14.73 ? 114 PHE C CA  1 
ATOM   4496 C C   . PHE C 1 112 ? -10.143 -31.367 -30.428 1.00 17.26 ? 114 PHE C C   1 
ATOM   4497 O O   . PHE C 1 112 ? -10.000 -31.954 -31.507 1.00 15.35 ? 114 PHE C O   1 
ATOM   4498 C CB  . PHE C 1 112 ? -12.570 -31.022 -29.904 1.00 15.73 ? 114 PHE C CB  1 
ATOM   4499 C CG  . PHE C 1 112 ? -13.457 -30.194 -29.041 1.00 17.94 ? 114 PHE C CG  1 
ATOM   4500 C CD1 . PHE C 1 112 ? -13.364 -30.253 -27.665 1.00 16.70 ? 114 PHE C CD1 1 
ATOM   4501 C CD2 . PHE C 1 112 ? -14.353 -29.302 -29.612 1.00 14.45 ? 114 PHE C CD2 1 
ATOM   4502 C CE1 . PHE C 1 112 ? -14.179 -29.474 -26.869 1.00 18.80 ? 114 PHE C CE1 1 
ATOM   4503 C CE2 . PHE C 1 112 ? -15.171 -28.520 -28.810 1.00 16.72 ? 114 PHE C CE2 1 
ATOM   4504 C CZ  . PHE C 1 112 ? -15.075 -28.604 -27.447 1.00 16.53 ? 114 PHE C CZ  1 
ATOM   4505 N N   . GLU C 1 113 ? -9.341  -31.548 -29.383 1.00 17.36 ? 115 GLU C N   1 
ATOM   4506 C CA  . GLU C 1 113 ? -8.364  -32.629 -29.289 1.00 16.34 ? 115 GLU C CA  1 
ATOM   4507 C C   . GLU C 1 113 ? -8.693  -33.312 -27.974 1.00 19.70 ? 115 GLU C C   1 
ATOM   4508 O O   . GLU C 1 113 ? -8.512  -32.709 -26.913 1.00 19.79 ? 115 GLU C O   1 
ATOM   4509 C CB  . GLU C 1 113 ? -6.939  -32.081 -29.296 1.00 17.49 ? 115 GLU C CB  1 
ATOM   4510 C CG  . GLU C 1 113 ? -6.607  -31.449 -30.639 1.00 15.03 ? 115 GLU C CG  1 
ATOM   4511 C CD  . GLU C 1 113 ? -5.170  -30.994 -30.771 1.00 18.84 ? 115 GLU C CD  1 
ATOM   4512 O OE1 . GLU C 1 113 ? -4.354  -31.240 -29.856 1.00 19.98 ? 115 GLU C OE1 1 
ATOM   4513 O OE2 . GLU C 1 113 ? -4.880  -30.356 -31.797 1.00 26.39 ? 115 GLU C OE2 1 
ATOM   4514 N N   . GLY C 1 114 ? -9.226  -34.532 -28.039 1.00 22.10 ? 116 GLY C N   1 
ATOM   4515 C CA  . GLY C 1 114 ? -9.808  -35.103 -26.832 1.00 20.02 ? 116 GLY C CA  1 
ATOM   4516 C C   . GLY C 1 114 ? -10.937 -34.210 -26.366 1.00 21.67 ? 116 GLY C C   1 
ATOM   4517 O O   . GLY C 1 114 ? -11.758 -33.762 -27.167 1.00 17.48 ? 116 GLY C O   1 
ATOM   4518 N N   . ASP C 1 115 ? -10.978 -33.912 -25.064 1.00 20.74 ? 117 ASP C N   1 
ATOM   4519 C CA  . ASP C 1 115 ? -11.983 -33.015 -24.500 1.00 20.25 ? 117 ASP C CA  1 
ATOM   4520 C C   . ASP C 1 115 ? -11.502 -31.564 -24.415 1.00 21.71 ? 117 ASP C C   1 
ATOM   4521 O O   . ASP C 1 115 ? -12.166 -30.732 -23.782 1.00 19.05 ? 117 ASP C O   1 
ATOM   4522 C CB  . ASP C 1 115 ? -12.401 -33.501 -23.110 1.00 22.85 ? 117 ASP C CB  1 
ATOM   4523 C CG  . ASP C 1 115 ? -13.304 -34.724 -23.160 1.00 29.92 ? 117 ASP C CG  1 
ATOM   4524 O OD1 . ASP C 1 115 ? -13.968 -34.956 -24.195 1.00 28.26 ? 117 ASP C OD1 1 
ATOM   4525 O OD2 . ASP C 1 115 ? -13.325 -35.472 -22.164 1.00 33.65 ? 117 ASP C OD2 1 
ATOM   4526 N N   . THR C 1 116 ? -10.370 -31.246 -25.025 1.00 17.32 ? 118 THR C N   1 
ATOM   4527 C CA  . THR C 1 116 ? -9.797  -29.909 -24.959 1.00 16.75 ? 118 THR C CA  1 
ATOM   4528 C C   . THR C 1 116 ? -10.028 -29.149 -26.253 1.00 13.88 ? 118 THR C C   1 
ATOM   4529 O O   . THR C 1 116 ? -9.821  -29.684 -27.344 1.00 15.60 ? 118 THR C O   1 
ATOM   4530 C CB  . THR C 1 116 ? -8.300  -29.986 -24.663 1.00 17.06 ? 118 THR C CB  1 
ATOM   4531 O OG1 . THR C 1 116 ? -8.102  -30.671 -23.418 1.00 16.10 ? 118 THR C OG1 1 
ATOM   4532 C CG2 . THR C 1 116 ? -7.684  -28.617 -24.601 1.00 16.13 ? 118 THR C CG2 1 
ATOM   4533 N N   . LEU C 1 117 ? -10.441 -27.885 -26.120 1.00 14.23 ? 119 LEU C N   1 
ATOM   4534 C CA  . LEU C 1 117 ? -10.540 -26.980 -27.257 1.00 12.11 ? 119 LEU C CA  1 
ATOM   4535 C C   . LEU C 1 117 ? -9.169  -26.354 -27.498 1.00 11.69 ? 119 LEU C C   1 
ATOM   4536 O O   . LEU C 1 117 ? -8.650  -25.627 -26.638 1.00 12.54 ? 119 LEU C O   1 
ATOM   4537 C CB  . LEU C 1 117 ? -11.597 -25.903 -26.992 1.00 14.54 ? 119 LEU C CB  1 
ATOM   4538 C CG  . LEU C 1 117 ? -12.088 -25.060 -28.178 1.00 15.81 ? 119 LEU C CG  1 
ATOM   4539 C CD1 . LEU C 1 117 ? -11.089 -23.959 -28.549 1.00 13.18 ? 119 LEU C CD1 1 
ATOM   4540 C CD2 . LEU C 1 117 ? -12.408 -25.931 -29.392 1.00 14.29 ? 119 LEU C CD2 1 
ATOM   4541 N N   . VAL C 1 118 ? -8.585  -26.622 -28.663 1.00 11.48 ? 120 VAL C N   1 
ATOM   4542 C CA  . VAL C 1 118 ? -7.228  -26.190 -28.992 1.00 11.00 ? 120 VAL C CA  1 
ATOM   4543 C C   . VAL C 1 118 ? -7.265  -25.130 -30.081 1.00 12.53 ? 120 VAL C C   1 
ATOM   4544 O O   . VAL C 1 118 ? -7.864  -25.339 -31.140 1.00 12.50 ? 120 VAL C O   1 
ATOM   4545 C CB  . VAL C 1 118 ? -6.361  -27.375 -29.439 1.00 14.54 ? 120 VAL C CB  1 
ATOM   4546 C CG1 . VAL C 1 118 ? -4.947  -26.895 -29.717 1.00 14.20 ? 120 VAL C CG1 1 
ATOM   4547 C CG2 . VAL C 1 118 ? -6.373  -28.446 -28.366 1.00 12.28 ? 120 VAL C CG2 1 
ATOM   4548 N N   . ASN C 1 119 ? -6.575  -24.012 -29.838 1.00 12.49 ? 121 ASN C N   1 
ATOM   4549 C CA  . ASN C 1 119 ? -6.355  -22.966 -30.835 1.00 13.53 ? 121 ASN C CA  1 
ATOM   4550 C C   . ASN C 1 119 ? -4.870  -22.987 -31.205 1.00 13.12 ? 121 ASN C C   1 
ATOM   4551 O O   . ASN C 1 119 ? -4.022  -22.585 -30.405 1.00 13.47 ? 121 ASN C O   1 
ATOM   4552 C CB  . ASN C 1 119 ? -6.775  -21.611 -30.258 1.00 11.28 ? 121 ASN C CB  1 
ATOM   4553 C CG  . ASN C 1 119 ? -6.594  -20.483 -31.232 1.00 14.04 ? 121 ASN C CG  1 
ATOM   4554 O OD1 . ASN C 1 119 ? -6.481  -20.709 -32.438 1.00 12.64 ? 121 ASN C OD1 1 
ATOM   4555 N ND2 . ASN C 1 119 ? -6.593  -19.246 -30.723 1.00 13.58 ? 121 ASN C ND2 1 
ATOM   4556 N N   . ARG C 1 120 ? -4.545  -23.479 -32.397 1.00 12.45 ? 122 ARG C N   1 
ATOM   4557 C CA  . ARG C 1 120 ? -3.159  -23.589 -32.852 1.00 13.32 ? 122 ARG C CA  1 
ATOM   4558 C C   . ARG C 1 120 ? -2.921  -22.580 -33.971 1.00 14.62 ? 122 ARG C C   1 
ATOM   4559 O O   . ARG C 1 120 ? -3.631  -22.596 -34.982 1.00 12.94 ? 122 ARG C O   1 
ATOM   4560 C CB  . ARG C 1 120 ? -2.842  -25.012 -33.321 1.00 14.64 ? 122 ARG C CB  1 
ATOM   4561 C CG  . ARG C 1 120 ? -1.345  -25.341 -33.414 1.00 22.89 ? 122 ARG C CG  1 
ATOM   4562 C CD  . ARG C 1 120 ? -1.109  -26.836 -33.713 1.00 21.33 ? 122 ARG C CD  1 
ATOM   4563 N NE  . ARG C 1 120 ? -1.509  -27.722 -32.622 1.00 24.42 ? 122 ARG C NE  1 
ATOM   4564 C CZ  . ARG C 1 120 ? -0.821  -27.887 -31.496 1.00 22.81 ? 122 ARG C CZ  1 
ATOM   4565 N NH1 . ARG C 1 120 ? 0.350   -27.298 -31.307 1.00 19.42 ? 122 ARG C NH1 1 
ATOM   4566 N NH2 . ARG C 1 120 ? -1.305  -28.690 -30.551 1.00 21.88 ? 122 ARG C NH2 1 
ATOM   4567 N N   . ILE C 1 121 ? -1.913  -21.719 -33.794 1.00 13.47 ? 123 ILE C N   1 
ATOM   4568 C CA  . ILE C 1 121 ? -1.749  -20.518 -34.606 1.00 14.78 ? 123 ILE C CA  1 
ATOM   4569 C C   . ILE C 1 121 ? -0.346  -20.437 -35.192 1.00 12.84 ? 123 ILE C C   1 
ATOM   4570 O O   . ILE C 1 121 ? 0.648   -20.659 -34.491 1.00 14.78 ? 123 ILE C O   1 
ATOM   4571 C CB  . ILE C 1 121 ? -2.007  -19.249 -33.774 1.00 13.21 ? 123 ILE C CB  1 
ATOM   4572 C CG1 . ILE C 1 121 ? -3.298  -19.407 -32.963 1.00 12.36 ? 123 ILE C CG1 1 
ATOM   4573 C CG2 . ILE C 1 121 ? -2.016  -18.031 -34.701 1.00 13.74 ? 123 ILE C CG2 1 
ATOM   4574 C CD1 . ILE C 1 121 ? -3.240  -18.698 -31.608 1.00 12.84 ? 123 ILE C CD1 1 
ATOM   4575 N N   . GLU C 1 122 ? -0.273  -20.045 -36.462 1.00 13.36 ? 124 GLU C N   1 
ATOM   4576 C CA  . GLU C 1 122 ? 0.946   -19.550 -37.081 1.00 12.18 ? 124 GLU C CA  1 
ATOM   4577 C C   . GLU C 1 122 ? 0.782   -18.063 -37.358 1.00 14.72 ? 124 GLU C C   1 
ATOM   4578 O O   . GLU C 1 122 ? -0.214  -17.648 -37.966 1.00 14.53 ? 124 GLU C O   1 
ATOM   4579 C CB  . GLU C 1 122 ? 1.234   -20.293 -38.388 1.00 17.57 ? 124 GLU C CB  1 
ATOM   4580 C CG  . GLU C 1 122 ? 1.828   -21.661 -38.204 1.00 21.89 ? 124 GLU C CG  1 
ATOM   4581 C CD  . GLU C 1 122 ? 2.231   -22.297 -39.535 1.00 35.20 ? 124 GLU C CD  1 
ATOM   4582 O OE1 . GLU C 1 122 ? 2.916   -21.635 -40.356 1.00 36.19 ? 124 GLU C OE1 1 
ATOM   4583 O OE2 . GLU C 1 122 ? 1.860   -23.466 -39.744 1.00 39.35 ? 124 GLU C OE2 1 
ATOM   4584 N N   . LEU C 1 123 ? 1.747   -17.264 -36.915 1.00 14.25 ? 125 LEU C N   1 
ATOM   4585 C CA  . LEU C 1 123 ? 1.706   -15.817 -37.080 1.00 11.53 ? 125 LEU C CA  1 
ATOM   4586 C C   . LEU C 1 123 ? 2.963   -15.379 -37.805 1.00 16.00 ? 125 LEU C C   1 
ATOM   4587 O O   . LEU C 1 123 ? 4.070   -15.733 -37.390 1.00 15.99 ? 125 LEU C O   1 
ATOM   4588 C CB  . LEU C 1 123 ? 1.613   -15.107 -35.713 1.00 11.47 ? 125 LEU C CB  1 
ATOM   4589 C CG  . LEU C 1 123 ? 1.600   -13.567 -35.664 1.00 13.25 ? 125 LEU C CG  1 
ATOM   4590 C CD1 . LEU C 1 123 ? 0.724   -13.096 -34.492 1.00 10.80 ? 125 LEU C CD1 1 
ATOM   4591 C CD2 . LEU C 1 123 ? 2.996   -12.900 -35.610 1.00 12.40 ? 125 LEU C CD2 1 
ATOM   4592 N N   . LYS C 1 124 ? 2.801   -14.590 -38.864 1.00 14.88 ? 126 LYS C N   1 
ATOM   4593 C CA  . LYS C 1 124 ? 3.944   -14.036 -39.577 1.00 13.25 ? 126 LYS C CA  1 
ATOM   4594 C C   . LYS C 1 124 ? 3.753   -12.527 -39.665 1.00 15.63 ? 126 LYS C C   1 
ATOM   4595 O O   . LYS C 1 124 ? 2.731   -12.060 -40.175 1.00 13.49 ? 126 LYS C O   1 
ATOM   4596 C CB  . LYS C 1 124 ? 4.073   -14.664 -40.968 1.00 19.11 ? 126 LYS C CB  1 
ATOM   4597 C CG  . LYS C 1 124 ? 5.197   -14.085 -41.825 1.00 26.35 ? 126 LYS C CG  1 
ATOM   4598 C CD  . LYS C 1 124 ? 6.523   -14.803 -41.530 1.00 30.34 ? 126 LYS C CD  1 
ATOM   4599 C CE  . LYS C 1 124 ? 7.678   -14.230 -42.346 1.00 34.49 ? 126 LYS C CE  1 
ATOM   4600 N NZ  . LYS C 1 124 ? 7.523   -14.495 -43.810 1.00 41.89 ? 126 LYS C NZ  1 
ATOM   4601 N N   . GLY C 1 125 ? 4.714   -11.776 -39.144 1.00 16.32 ? 127 GLY C N   1 
ATOM   4602 C CA  . GLY C 1 125 ? 4.697   -10.326 -39.218 1.00 16.12 ? 127 GLY C CA  1 
ATOM   4603 C C   . GLY C 1 125 ? 5.864   -9.848  -40.062 1.00 16.90 ? 127 GLY C C   1 
ATOM   4604 O O   . GLY C 1 125 ? 6.993   -10.328 -39.907 1.00 16.83 ? 127 GLY C O   1 
ATOM   4605 N N   . ILE C 1 126 ? 5.587   -8.899  -40.954 1.00 15.44 ? 128 ILE C N   1 
ATOM   4606 C CA  . ILE C 1 126 ? 6.610   -8.305  -41.807 1.00 19.85 ? 128 ILE C CA  1 
ATOM   4607 C C   . ILE C 1 126 ? 6.395   -6.799  -41.878 1.00 20.97 ? 128 ILE C C   1 
ATOM   4608 O O   . ILE C 1 126 ? 5.374   -6.263  -41.448 1.00 16.34 ? 128 ILE C O   1 
ATOM   4609 C CB  . ILE C 1 126 ? 6.626   -8.884  -43.237 1.00 20.58 ? 128 ILE C CB  1 
ATOM   4610 C CG1 . ILE C 1 126 ? 5.315   -8.549  -43.968 1.00 18.15 ? 128 ILE C CG1 1 
ATOM   4611 C CG2 . ILE C 1 126 ? 6.939   -10.384 -43.211 1.00 24.12 ? 128 ILE C CG2 1 
ATOM   4612 C CD1 . ILE C 1 126 ? 5.088   -9.331  -45.243 1.00 24.29 ? 128 ILE C CD1 1 
ATOM   4613 N N   . ASP C 1 127 ? 7.388   -6.123  -42.444 1.00 20.71 ? 129 ASP C N   1 
ATOM   4614 C CA  . ASP C 1 127 ? 7.348   -4.693  -42.740 1.00 23.98 ? 129 ASP C CA  1 
ATOM   4615 C C   . ASP C 1 127 ? 7.324   -3.831  -41.474 1.00 21.88 ? 129 ASP C C   1 
ATOM   4616 O O   . ASP C 1 127 ? 6.894   -2.674  -41.526 1.00 22.20 ? 129 ASP C O   1 
ATOM   4617 C CB  . ASP C 1 127 ? 6.145   -4.341  -43.630 1.00 19.83 ? 129 ASP C CB  1 
ATOM   4618 C CG  . ASP C 1 127 ? 6.158   -5.078  -44.984 1.00 26.59 ? 129 ASP C CG  1 
ATOM   4619 O OD1 . ASP C 1 127 ? 7.251   -5.386  -45.505 1.00 23.79 ? 129 ASP C OD1 1 
ATOM   4620 O OD2 . ASP C 1 127 ? 5.049   -5.337  -45.533 1.00 24.77 ? 129 ASP C OD2 1 
ATOM   4621 N N   . PHE C 1 128 ? 7.778   -4.349  -40.331 1.00 17.55 ? 130 PHE C N   1 
ATOM   4622 C CA  . PHE C 1 128 ? 7.729   -3.590  -39.086 1.00 18.53 ? 130 PHE C CA  1 
ATOM   4623 C C   . PHE C 1 128 ? 8.963   -2.712  -38.928 1.00 21.13 ? 130 PHE C C   1 
ATOM   4624 O O   . PHE C 1 128 ? 10.058  -3.041  -39.393 1.00 18.79 ? 130 PHE C O   1 
ATOM   4625 C CB  . PHE C 1 128 ? 7.604   -4.508  -37.857 1.00 20.66 ? 130 PHE C CB  1 
ATOM   4626 C CG  . PHE C 1 128 ? 6.207   -5.028  -37.628 1.00 19.20 ? 130 PHE C CG  1 
ATOM   4627 C CD1 . PHE C 1 128 ? 5.304   -4.326  -36.838 1.00 17.27 ? 130 PHE C CD1 1 
ATOM   4628 C CD2 . PHE C 1 128 ? 5.795   -6.216  -38.217 1.00 16.66 ? 130 PHE C CD2 1 
ATOM   4629 C CE1 . PHE C 1 128 ? 4.008   -4.806  -36.633 1.00 15.64 ? 130 PHE C CE1 1 
ATOM   4630 C CE2 . PHE C 1 128 ? 4.496   -6.703  -38.024 1.00 16.32 ? 130 PHE C CE2 1 
ATOM   4631 C CZ  . PHE C 1 128 ? 3.598   -5.984  -37.229 1.00 12.59 ? 130 PHE C CZ  1 
ATOM   4632 N N   . LYS C 1 129 ? 8.771   -1.588  -38.260 1.00 19.29 ? 131 LYS C N   1 
ATOM   4633 C CA  . LYS C 1 129 ? 9.869   -0.701  -37.906 1.00 21.67 ? 131 LYS C CA  1 
ATOM   4634 C C   . LYS C 1 129 ? 10.485  -1.181  -36.598 1.00 25.28 ? 131 LYS C C   1 
ATOM   4635 O O   . LYS C 1 129 ? 9.764   -1.396  -35.619 1.00 23.90 ? 131 LYS C O   1 
ATOM   4636 C CB  . LYS C 1 129 ? 9.363   0.735   -37.778 1.00 22.13 ? 131 LYS C CB  1 
ATOM   4637 C CG  . LYS C 1 129 ? 8.772   1.255   -39.087 1.00 22.02 ? 131 LYS C CG  1 
ATOM   4638 C CD  . LYS C 1 129 ? 8.004   2.563   -38.912 1.00 27.39 ? 131 LYS C CD  1 
ATOM   4639 C CE  . LYS C 1 129 ? 7.507   3.072   -40.267 1.00 29.26 ? 131 LYS C CE  1 
ATOM   4640 N N   . GLU C 1 130 ? 11.813  -1.362  -36.582 1.00 23.37 ? 132 GLU C N   1 
ATOM   4641 C CA  . GLU C 1 130 ? 12.459  -1.878  -35.378 1.00 27.13 ? 132 GLU C CA  1 
ATOM   4642 C C   . GLU C 1 130 ? 12.326  -0.929  -34.201 1.00 28.96 ? 132 GLU C C   1 
ATOM   4643 O O   . GLU C 1 130 ? 12.404  -1.373  -33.053 1.00 32.42 ? 132 GLU C O   1 
ATOM   4644 C CB  . GLU C 1 130 ? 13.942  -2.166  -35.619 1.00 30.70 ? 132 GLU C CB  1 
ATOM   4645 C CG  . GLU C 1 130 ? 14.155  -3.469  -36.327 1.00 25.71 ? 132 GLU C CG  1 
ATOM   4646 C CD  . GLU C 1 130 ? 14.053  -4.694  -35.417 1.00 32.45 ? 132 GLU C CD  1 
ATOM   4647 O OE1 . GLU C 1 130 ? 14.012  -4.563  -34.166 1.00 30.11 ? 132 GLU C OE1 1 
ATOM   4648 O OE2 . GLU C 1 130 ? 13.938  -5.796  -35.985 1.00 29.95 ? 132 GLU C OE2 1 
ATOM   4649 N N   . ASP C 1 131 ? 12.136  0.365   -34.455 1.00 29.82 ? 133 ASP C N   1 
ATOM   4650 C CA  . ASP C 1 131 ? 11.883  1.334   -33.397 1.00 35.71 ? 133 ASP C CA  1 
ATOM   4651 C C   . ASP C 1 131 ? 10.437  1.812   -33.361 1.00 28.88 ? 133 ASP C C   1 
ATOM   4652 O O   . ASP C 1 131 ? 10.151  2.826   -32.725 1.00 32.75 ? 133 ASP C O   1 
ATOM   4653 C CB  . ASP C 1 131 ? 12.811  2.542   -33.521 1.00 40.17 ? 133 ASP C CB  1 
ATOM   4654 C CG  . ASP C 1 131 ? 13.250  3.064   -32.171 1.00 47.72 ? 133 ASP C CG  1 
ATOM   4655 O OD1 . ASP C 1 131 ? 12.827  2.474   -31.150 1.00 46.10 ? 133 ASP C OD1 1 
ATOM   4656 O OD2 . ASP C 1 131 ? 13.982  4.078   -32.126 1.00 57.08 ? 133 ASP C OD2 1 
ATOM   4657 N N   . GLY C 1 132 ? 9.528   1.115   -34.033 1.00 28.03 ? 134 GLY C N   1 
ATOM   4658 C CA  . GLY C 1 132 ? 8.128   1.471   -33.996 1.00 24.54 ? 134 GLY C CA  1 
ATOM   4659 C C   . GLY C 1 132 ? 7.490   1.094   -32.672 1.00 22.93 ? 134 GLY C C   1 
ATOM   4660 O O   . GLY C 1 132 ? 8.145   0.663   -31.722 1.00 20.41 ? 134 GLY C O   1 
ATOM   4661 N N   . ASN C 1 133 ? 6.166   1.254   -32.623 1.00 17.98 ? 135 ASN C N   1 
ATOM   4662 C CA  . ASN C 1 133 ? 5.448   1.001   -31.380 1.00 20.13 ? 135 ASN C CA  1 
ATOM   4663 C C   . ASN C 1 133 ? 5.360   -0.480  -31.048 1.00 17.89 ? 135 ASN C C   1 
ATOM   4664 O O   . ASN C 1 133 ? 5.088   -0.828  -29.891 1.00 18.52 ? 135 ASN C O   1 
ATOM   4665 C CB  . ASN C 1 133 ? 4.044   1.589   -31.457 1.00 17.60 ? 135 ASN C CB  1 
ATOM   4666 C CG  . ASN C 1 133 ? 4.055   3.091   -31.573 1.00 21.21 ? 135 ASN C CG  1 
ATOM   4667 O OD1 . ASN C 1 133 ? 4.945   3.752   -31.041 1.00 22.38 ? 135 ASN C OD1 1 
ATOM   4668 N ND2 . ASN C 1 133 ? 3.094   3.638   -32.305 1.00 22.02 ? 135 ASN C ND2 1 
ATOM   4669 N N   . ILE C 1 134 ? 5.560   -1.354  -32.030 1.00 16.35 ? 136 ILE C N   1 
ATOM   4670 C CA  . ILE C 1 134 ? 5.366   -2.785  -31.811 1.00 16.29 ? 136 ILE C CA  1 
ATOM   4671 C C   . ILE C 1 134 ? 6.709   -3.394  -31.432 1.00 18.93 ? 136 ILE C C   1 
ATOM   4672 O O   . ILE C 1 134 ? 6.900   -3.819  -30.289 1.00 17.60 ? 136 ILE C O   1 
ATOM   4673 C CB  . ILE C 1 134 ? 4.755   -3.474  -33.047 1.00 17.12 ? 136 ILE C CB  1 
ATOM   4674 C CG1 . ILE C 1 134 ? 3.247   -3.224  -33.109 1.00 16.13 ? 136 ILE C CG1 1 
ATOM   4675 C CG2 . ILE C 1 134 ? 4.936   -4.995  -32.967 1.00 17.65 ? 136 ILE C CG2 1 
ATOM   4676 C CD1 . ILE C 1 134 ? 2.880   -1.845  -33.563 1.00 19.11 ? 136 ILE C CD1 1 
ATOM   4677 N N   . LEU C 1 135 ? 7.663   -3.399  -32.370 1.00 18.95 ? 137 LEU C N   1 
ATOM   4678 C CA  . LEU C 1 135 ? 8.970   -3.975  -32.077 1.00 20.47 ? 137 LEU C CA  1 
ATOM   4679 C C   . LEU C 1 135 ? 9.696   -3.172  -31.007 1.00 21.58 ? 137 LEU C C   1 
ATOM   4680 O O   . LEU C 1 135 ? 10.539  -3.725  -30.283 1.00 23.03 ? 137 LEU C O   1 
ATOM   4681 C CB  . LEU C 1 135 ? 9.793   -4.059  -33.366 1.00 22.16 ? 137 LEU C CB  1 
ATOM   4682 C CG  . LEU C 1 135 ? 9.366   -5.166  -34.345 1.00 22.60 ? 137 LEU C CG  1 
ATOM   4683 C CD1 . LEU C 1 135 ? 10.342  -5.308  -35.512 1.00 20.32 ? 137 LEU C CD1 1 
ATOM   4684 C CD2 . LEU C 1 135 ? 9.175   -6.516  -33.656 1.00 21.88 ? 137 LEU C CD2 1 
ATOM   4685 N N   . GLY C 1 136 ? 9.347   -1.897  -30.849 1.00 19.88 ? 138 GLY C N   1 
ATOM   4686 C CA  . GLY C 1 136 ? 9.923   -1.099  -29.790 1.00 19.89 ? 138 GLY C CA  1 
ATOM   4687 C C   . GLY C 1 136 ? 9.179   -1.127  -28.474 1.00 20.98 ? 138 GLY C C   1 
ATOM   4688 O O   . GLY C 1 136 ? 9.552   -0.374  -27.569 1.00 20.59 ? 138 GLY C O   1 
ATOM   4689 N N   . HIS C 1 137 ? 8.147   -1.966  -28.336 1.00 19.99 ? 139 HIS C N   1 
ATOM   4690 C CA  . HIS C 1 137 ? 7.395   -2.133  -27.090 1.00 16.22 ? 139 HIS C CA  1 
ATOM   4691 C C   . HIS C 1 137 ? 6.977   -0.778  -26.508 1.00 22.24 ? 139 HIS C C   1 
ATOM   4692 O O   . HIS C 1 137 ? 7.347   -0.408  -25.390 1.00 18.91 ? 139 HIS C O   1 
ATOM   4693 C CB  . HIS C 1 137 ? 8.207   -2.934  -26.056 1.00 20.25 ? 139 HIS C CB  1 
ATOM   4694 C CG  . HIS C 1 137 ? 8.426   -4.378  -26.418 1.00 20.95 ? 139 HIS C CG  1 
ATOM   4695 N ND1 . HIS C 1 137 ? 9.539   -4.814  -27.110 1.00 22.59 ? 139 HIS C ND1 1 
ATOM   4696 C CD2 . HIS C 1 137 ? 7.705   -5.490  -26.131 1.00 20.26 ? 139 HIS C CD2 1 
ATOM   4697 C CE1 . HIS C 1 137 ? 9.469   -6.127  -27.271 1.00 20.80 ? 139 HIS C CE1 1 
ATOM   4698 N NE2 . HIS C 1 137 ? 8.373   -6.561  -26.678 1.00 19.40 ? 139 HIS C NE2 1 
ATOM   4699 N N   . LYS C 1 138 ? 6.179   -0.034  -27.279 1.00 18.25 ? 140 LYS C N   1 
ATOM   4700 C CA  . LYS C 1 138 ? 5.732   1.289   -26.854 1.00 19.85 ? 140 LYS C CA  1 
ATOM   4701 C C   . LYS C 1 138 ? 4.236   1.347   -26.568 1.00 23.56 ? 140 LYS C C   1 
ATOM   4702 O O   . LYS C 1 138 ? 3.673   2.443   -26.463 1.00 20.81 ? 140 LYS C O   1 
ATOM   4703 C CB  . LYS C 1 138 ? 6.107   2.342   -27.895 1.00 22.75 ? 140 LYS C CB  1 
ATOM   4704 C CG  . LYS C 1 138 ? 7.606   2.442   -28.154 1.00 20.34 ? 140 LYS C CG  1 
ATOM   4705 C CD  . LYS C 1 138 ? 7.910   3.477   -29.200 1.00 24.71 ? 140 LYS C CD  1 
ATOM   4706 C CE  . LYS C 1 138 ? 9.397   3.481   -29.546 1.00 27.33 ? 140 LYS C CE  1 
ATOM   4707 N NZ  . LYS C 1 138 ? 9.711   4.504   -30.578 1.00 29.65 ? 140 LYS C NZ  1 
ATOM   4708 N N   . LEU C 1 139 ? 3.588   0.195   -26.418 1.00 18.78 ? 141 LEU C N   1 
ATOM   4709 C CA  . LEU C 1 139 ? 2.157   0.120   -26.154 1.00 20.72 ? 141 LEU C CA  1 
ATOM   4710 C C   . LEU C 1 139 ? 1.910   -0.203  -24.690 1.00 19.65 ? 141 LEU C C   1 
ATOM   4711 O O   . LEU C 1 139 ? 2.645   -0.989  -24.091 1.00 21.40 ? 141 LEU C O   1 
ATOM   4712 C CB  . LEU C 1 139 ? 1.499   -0.951  -27.029 1.00 16.81 ? 141 LEU C CB  1 
ATOM   4713 C CG  . LEU C 1 139 ? 1.653   -0.757  -28.530 1.00 18.19 ? 141 LEU C CG  1 
ATOM   4714 C CD1 . LEU C 1 139 ? 0.902   -1.854  -29.259 1.00 19.40 ? 141 LEU C CD1 1 
ATOM   4715 C CD2 . LEU C 1 139 ? 1.169   0.642   -28.975 1.00 18.25 ? 141 LEU C CD2 1 
ATOM   4716 N N   . GLU C 1 140 ? 0.860   0.398   -24.126 1.00 23.29 ? 142 GLU C N   1 
ATOM   4717 C CA  . GLU C 1 140 ? 0.463   0.156   -22.745 1.00 21.80 ? 142 GLU C CA  1 
ATOM   4718 C C   . GLU C 1 140 ? -0.114  -1.250  -22.575 1.00 21.17 ? 142 GLU C C   1 
ATOM   4719 O O   . GLU C 1 140 ? -0.703  -1.817  -23.497 1.00 17.53 ? 142 GLU C O   1 
ATOM   4720 C CB  . GLU C 1 140 ? -0.588  1.186   -22.325 1.00 25.39 ? 142 GLU C CB  1 
ATOM   4721 C CG  . GLU C 1 140 ? -0.095  2.614   -22.424 1.00 28.57 ? 142 GLU C CG  1 
ATOM   4722 C CD  . GLU C 1 140 ? -1.126  3.650   -22.004 1.00 33.48 ? 142 GLU C CD  1 
ATOM   4723 O OE1 . GLU C 1 140 ? -0.789  4.850   -22.072 1.00 38.33 ? 142 GLU C OE1 1 
ATOM   4724 O OE2 . GLU C 1 140 ? -2.271  3.284   -21.638 1.00 36.48 ? 142 GLU C OE2 1 
ATOM   4725 N N   . TYR C 1 141 ? 0.026   -1.792  -21.362 1.00 18.19 ? 143 TYR C N   1 
ATOM   4726 C CA  . TYR C 1 141 ? -0.471  -3.131  -21.028 1.00 19.07 ? 143 TYR C CA  1 
ATOM   4727 C C   . TYR C 1 141 ? -1.903  -3.010  -20.517 1.00 21.01 ? 143 TYR C C   1 
ATOM   4728 O O   . TYR C 1 141 ? -2.187  -3.064  -19.315 1.00 21.17 ? 143 TYR C O   1 
ATOM   4729 C CB  . TYR C 1 141 ? 0.433   -3.812  -20.006 1.00 20.84 ? 143 TYR C CB  1 
ATOM   4730 C CG  . TYR C 1 141 ? 0.062   -5.264  -19.727 1.00 19.10 ? 143 TYR C CG  1 
ATOM   4731 C CD1 . TYR C 1 141 ? 0.327   -6.263  -20.662 1.00 15.73 ? 143 TYR C CD1 1 
ATOM   4732 C CD2 . TYR C 1 141 ? -0.581  -5.629  -18.550 1.00 20.47 ? 143 TYR C CD2 1 
ATOM   4733 C CE1 . TYR C 1 141 ? -0.013  -7.591  -20.418 1.00 16.66 ? 143 TYR C CE1 1 
ATOM   4734 C CE2 . TYR C 1 141 ? -0.926  -6.962  -18.296 1.00 14.17 ? 143 TYR C CE2 1 
ATOM   4735 C CZ  . TYR C 1 141 ? -0.640  -7.931  -19.245 1.00 15.91 ? 143 TYR C CZ  1 
ATOM   4736 O OH  . TYR C 1 141 ? -0.975  -9.245  -19.015 1.00 13.68 ? 143 TYR C OH  1 
ATOM   4737 N N   . ASN C 1 142 ? -2.818  -2.833  -21.463 1.00 19.92 ? 144 ASN C N   1 
ATOM   4738 C CA  . ASN C 1 142 ? -4.254  -2.792  -21.210 1.00 21.16 ? 144 ASN C CA  1 
ATOM   4739 C C   . ASN C 1 142 ? -4.937  -3.078  -22.541 1.00 20.08 ? 144 ASN C C   1 
ATOM   4740 O O   . ASN C 1 142 ? -4.277  -3.451  -23.518 1.00 20.59 ? 144 ASN C O   1 
ATOM   4741 C CB  . ASN C 1 142 ? -4.702  -1.456  -20.585 1.00 21.82 ? 144 ASN C CB  1 
ATOM   4742 C CG  . ASN C 1 142 ? -4.297  -0.233  -21.401 1.00 29.07 ? 144 ASN C CG  1 
ATOM   4743 O OD1 . ASN C 1 142 ? -4.152  -0.293  -22.623 1.00 26.89 ? 144 ASN C OD1 1 
ATOM   4744 N ND2 . ASN C 1 142 ? -4.162  0.905   -20.723 1.00 30.61 ? 144 ASN C ND2 1 
ATOM   4745 N N   . TYR C 1 143 ? -6.251  -2.902  -22.594 1.00 16.28 ? 145 TYR C N   1 
ATOM   4746 C CA  . TYR C 1 143 ? -6.975  -3.316  -23.788 1.00 18.83 ? 145 TYR C CA  1 
ATOM   4747 C C   . TYR C 1 143 ? -8.214  -2.458  -24.008 1.00 21.87 ? 145 TYR C C   1 
ATOM   4748 O O   . TYR C 1 143 ? -8.908  -2.101  -23.055 1.00 20.27 ? 145 TYR C O   1 
ATOM   4749 C CB  . TYR C 1 143 ? -7.386  -4.797  -23.704 1.00 18.10 ? 145 TYR C CB  1 
ATOM   4750 C CG  . TYR C 1 143 ? -7.465  -5.406  -25.075 1.00 16.06 ? 145 TYR C CG  1 
ATOM   4751 C CD1 . TYR C 1 143 ? -6.312  -5.668  -25.796 1.00 16.69 ? 145 TYR C CD1 1 
ATOM   4752 C CD2 . TYR C 1 143 ? -8.688  -5.615  -25.698 1.00 15.66 ? 145 TYR C CD2 1 
ATOM   4753 C CE1 . TYR C 1 143 ? -6.372  -6.200  -27.079 1.00 13.74 ? 145 TYR C CE1 1 
ATOM   4754 C CE2 . TYR C 1 143 ? -8.752  -6.125  -26.990 1.00 15.42 ? 145 TYR C CE2 1 
ATOM   4755 C CZ  . TYR C 1 143 ? -7.582  -6.411  -27.667 1.00 13.55 ? 145 TYR C CZ  1 
ATOM   4756 O OH  . TYR C 1 143 ? -7.634  -6.923  -28.942 1.00 15.09 ? 145 TYR C OH  1 
ATOM   4757 N N   . ASN C 1 144 ? -8.492  -2.154  -25.277 1.00 17.05 ? 146 ASN C N   1 
ATOM   4758 C CA  . ASN C 1 144 ? -9.718  -1.481  -25.710 1.00 18.24 ? 146 ASN C CA  1 
ATOM   4759 C C   . ASN C 1 144 ? -10.464 -2.466  -26.601 1.00 17.17 ? 146 ASN C C   1 
ATOM   4760 O O   . ASN C 1 144 ? -10.097 -2.656  -27.766 1.00 16.24 ? 146 ASN C O   1 
ATOM   4761 C CB  . ASN C 1 144 ? -9.424  -0.196  -26.485 1.00 22.14 ? 146 ASN C CB  1 
ATOM   4762 C CG  . ASN C 1 144 ? -8.737  0.864   -25.643 1.00 24.18 ? 146 ASN C CG  1 
ATOM   4763 O OD1 . ASN C 1 144 ? -9.254  1.306   -24.614 1.00 27.82 ? 146 ASN C OD1 1 
ATOM   4764 N ND2 . ASN C 1 144 ? -7.551  1.276   -26.084 1.00 24.27 ? 146 ASN C ND2 1 
ATOM   4765 N N   . ASP C 1 145 ? -11.508 -3.093  -26.076 1.00 12.67 ? 147 ASP C N   1 
ATOM   4766 C CA  . ASP C 1 145 ? -12.237 -4.047  -26.893 1.00 13.90 ? 147 ASP C CA  1 
ATOM   4767 C C   . ASP C 1 145 ? -12.989 -3.350  -28.025 1.00 19.11 ? 147 ASP C C   1 
ATOM   4768 O O   . ASP C 1 145 ? -13.226 -2.141  -28.009 1.00 19.62 ? 147 ASP C O   1 
ATOM   4769 C CB  . ASP C 1 145 ? -13.187 -4.861  -26.023 1.00 13.74 ? 147 ASP C CB  1 
ATOM   4770 C CG  . ASP C 1 145 ? -12.438 -5.807  -25.108 1.00 15.05 ? 147 ASP C CG  1 
ATOM   4771 O OD1 . ASP C 1 145 ? -11.970 -6.838  -25.632 1.00 15.70 ? 147 ASP C OD1 1 
ATOM   4772 O OD2 . ASP C 1 145 ? -12.255 -5.497  -23.908 1.00 16.76 ? 147 ASP C OD2 1 
ATOM   4773 N N   . HIS C 1 146 ? -13.348 -4.139  -29.032 1.00 17.88 ? 148 HIS C N   1 
ATOM   4774 C CA  . HIS C 1 146 ? -14.171 -3.653  -30.123 1.00 17.94 ? 148 HIS C CA  1 
ATOM   4775 C C   . HIS C 1 146 ? -15.169 -4.733  -30.504 1.00 19.24 ? 148 HIS C C   1 
ATOM   4776 O O   . HIS C 1 146 ? -14.843 -5.925  -30.473 1.00 14.52 ? 148 HIS C O   1 
ATOM   4777 C CB  . HIS C 1 146 ? -13.327 -3.270  -31.339 1.00 18.49 ? 148 HIS C CB  1 
ATOM   4778 C CG  . HIS C 1 146 ? -14.050 -2.391  -32.312 1.00 19.55 ? 148 HIS C CG  1 
ATOM   4779 N ND1 . HIS C 1 146 ? -14.956 -2.882  -33.229 1.00 19.65 ? 148 HIS C ND1 1 
ATOM   4780 C CD2 . HIS C 1 146 ? -14.001 -1.054  -32.509 1.00 21.14 ? 148 HIS C CD2 1 
ATOM   4781 C CE1 . HIS C 1 146 ? -15.438 -1.881  -33.947 1.00 20.71 ? 148 HIS C CE1 1 
ATOM   4782 N NE2 . HIS C 1 146 ? -14.875 -0.762  -33.529 1.00 24.33 ? 148 HIS C NE2 1 
ATOM   4783 N N   . GLN C 1 147 ? -16.384 -4.307  -30.851 1.00 18.56 ? 149 GLN C N   1 
ATOM   4784 C CA  . GLN C 1 147 ? -17.399 -5.226  -31.347 1.00 20.32 ? 149 GLN C CA  1 
ATOM   4785 C C   . GLN C 1 147 ? -16.924 -5.838  -32.652 1.00 19.05 ? 149 GLN C C   1 
ATOM   4786 O O   . GLN C 1 147 ? -16.100 -5.264  -33.370 1.00 18.18 ? 149 GLN C O   1 
ATOM   4787 C CB  . GLN C 1 147 ? -18.720 -4.506  -31.614 1.00 22.84 ? 149 GLN C CB  1 
ATOM   4788 C CG  . GLN C 1 147 ? -18.583 -3.263  -32.501 1.00 25.31 ? 149 GLN C CG  1 
ATOM   4789 C CD  . GLN C 1 147 ? -19.889 -2.502  -32.623 1.00 30.25 ? 149 GLN C CD  1 
ATOM   4790 O OE1 . GLN C 1 147 ? -20.703 -2.505  -31.694 1.00 32.33 ? 149 GLN C OE1 1 
ATOM   4791 N NE2 . GLN C 1 147 ? -20.117 -1.875  -33.783 1.00 33.50 ? 149 GLN C NE2 1 
ATOM   4792 N N   . VAL C 1 148 ? -17.456 -7.016  -32.964 1.00 17.78 ? 150 VAL C N   1 
ATOM   4793 C CA  . VAL C 1 148 ? -17.095 -7.724  -34.178 1.00 16.22 ? 150 VAL C CA  1 
ATOM   4794 C C   . VAL C 1 148 ? -18.391 -8.086  -34.890 1.00 18.52 ? 150 VAL C C   1 
ATOM   4795 O O   . VAL C 1 148 ? -19.221 -8.822  -34.345 1.00 18.06 ? 150 VAL C O   1 
ATOM   4796 C CB  . VAL C 1 148 ? -16.254 -8.981  -33.888 1.00 18.60 ? 150 VAL C CB  1 
ATOM   4797 C CG1 . VAL C 1 148 ? -16.015 -9.742  -35.165 1.00 15.64 ? 150 VAL C CG1 1 
ATOM   4798 C CG2 . VAL C 1 148 ? -14.934 -8.591  -33.230 1.00 17.24 ? 150 VAL C CG2 1 
ATOM   4799 N N   . TYR C 1 149 ? -18.579 -7.545  -36.087 1.00 19.87 ? 151 TYR C N   1 
ATOM   4800 C CA  . TYR C 1 149 ? -19.810 -7.734  -36.848 1.00 20.18 ? 151 TYR C CA  1 
ATOM   4801 C C   . TYR C 1 149 ? -19.635 -8.944  -37.751 1.00 19.49 ? 151 TYR C C   1 
ATOM   4802 O O   . TYR C 1 149 ? -18.909 -8.881  -38.745 1.00 20.55 ? 151 TYR C O   1 
ATOM   4803 C CB  . TYR C 1 149 ? -20.126 -6.474  -37.645 1.00 19.85 ? 151 TYR C CB  1 
ATOM   4804 C CG  . TYR C 1 149 ? -21.437 -6.474  -38.408 1.00 22.87 ? 151 TYR C CG  1 
ATOM   4805 C CD1 . TYR C 1 149 ? -22.660 -6.334  -37.753 1.00 27.16 ? 151 TYR C CD1 1 
ATOM   4806 C CD2 . TYR C 1 149 ? -21.444 -6.539  -39.794 1.00 22.70 ? 151 TYR C CD2 1 
ATOM   4807 C CE1 . TYR C 1 149 ? -23.861 -6.302  -38.470 1.00 29.16 ? 151 TYR C CE1 1 
ATOM   4808 C CE2 . TYR C 1 149 ? -22.629 -6.501  -40.517 1.00 26.04 ? 151 TYR C CE2 1 
ATOM   4809 C CZ  . TYR C 1 149 ? -23.832 -6.381  -39.851 1.00 31.24 ? 151 TYR C CZ  1 
ATOM   4810 O OH  . TYR C 1 149 ? -25.000 -6.346  -40.579 1.00 35.48 ? 151 TYR C OH  1 
ATOM   4811 N N   . ILE C 1 150 ? -20.286 -10.046 -37.396 1.00 18.09 ? 152 ILE C N   1 
ATOM   4812 C CA  . ILE C 1 150 ? -20.112 -11.309 -38.098 1.00 18.45 ? 152 ILE C CA  1 
ATOM   4813 C C   . ILE C 1 150 ? -21.088 -11.378 -39.266 1.00 20.82 ? 152 ILE C C   1 
ATOM   4814 O O   . ILE C 1 150 ? -22.286 -11.120 -39.100 1.00 21.28 ? 152 ILE C O   1 
ATOM   4815 C CB  . ILE C 1 150 ? -20.302 -12.500 -37.144 1.00 19.29 ? 152 ILE C CB  1 
ATOM   4816 C CG1 . ILE C 1 150 ? -19.307 -12.370 -35.988 1.00 20.01 ? 152 ILE C CG1 1 
ATOM   4817 C CG2 . ILE C 1 150 ? -20.224 -13.833 -37.898 1.00 19.05 ? 152 ILE C CG2 1 
ATOM   4818 C CD1 . ILE C 1 150 ? -17.955 -12.958 -36.292 1.00 18.56 ? 152 ILE C CD1 1 
ATOM   4819 N N   . MET C 1 151 ? -20.568 -11.714 -40.454 1.00 20.55 ? 153 MET C N   1 
ATOM   4820 C CA  . MET C 1 151 ? -21.385 -11.898 -41.645 1.00 22.09 ? 153 MET C CA  1 
ATOM   4821 C C   . MET C 1 151 ? -21.073 -13.249 -42.267 1.00 24.82 ? 153 MET C C   1 
ATOM   4822 O O   . MET C 1 151 ? -19.915 -13.676 -42.303 1.00 21.12 ? 153 MET C O   1 
ATOM   4823 C CB  . MET C 1 151 ? -21.128 -10.795 -42.664 1.00 22.43 ? 153 MET C CB  1 
ATOM   4824 C CG  . MET C 1 151 ? -21.191 -9.405  -42.060 1.00 25.45 ? 153 MET C CG  1 
ATOM   4825 S SD  . MET C 1 151 ? -20.769 -8.162  -43.284 1.00 33.10 ? 153 MET C SD  1 
ATOM   4826 C CE  . MET C 1 151 ? -19.005 -7.977  -42.918 1.00 28.94 ? 153 MET C CE  1 
ATOM   4827 N N   . ALA C 1 152 ? -22.114 -13.920 -42.755 1.00 28.46 ? 154 ALA C N   1 
ATOM   4828 C CA  . ALA C 1 152 ? -21.924 -15.189 -43.440 1.00 30.38 ? 154 ALA C CA  1 
ATOM   4829 C C   . ALA C 1 152 ? -21.122 -14.998 -44.722 1.00 27.95 ? 154 ALA C C   1 
ATOM   4830 O O   . ALA C 1 152 ? -21.210 -13.968 -45.391 1.00 26.87 ? 154 ALA C O   1 
ATOM   4831 C CB  . ALA C 1 152 ? -23.275 -15.838 -43.759 1.00 27.33 ? 154 ALA C CB  1 
ATOM   4832 N N   . ASP C 1 153 ? -20.315 -16.005 -45.040 1.00 27.86 ? 155 ASP C N   1 
ATOM   4833 C CA  . ASP C 1 153 ? -19.582 -16.137 -46.297 1.00 33.06 ? 155 ASP C CA  1 
ATOM   4834 C C   . ASP C 1 153 ? -20.067 -17.424 -46.954 1.00 37.14 ? 155 ASP C C   1 
ATOM   4835 O O   . ASP C 1 153 ? -19.415 -18.465 -46.846 1.00 36.93 ? 155 ASP C O   1 
ATOM   4836 C CB  . ASP C 1 153 ? -18.087 -16.167 -46.040 1.00 32.06 ? 155 ASP C CB  1 
ATOM   4837 C CG  . ASP C 1 153 ? -17.286 -15.649 -47.206 1.00 41.19 ? 155 ASP C CG  1 
ATOM   4838 O OD1 . ASP C 1 153 ? -16.083 -15.984 -47.282 1.00 41.58 ? 155 ASP C OD1 1 
ATOM   4839 O OD2 . ASP C 1 153 ? -17.858 -14.917 -48.048 1.00 48.66 ? 155 ASP C OD2 1 
ATOM   4840 N N   . LYS C 1 154 ? -21.226 -17.354 -47.619 1.00 38.76 ? 156 LYS C N   1 
ATOM   4841 C CA  . LYS C 1 154 ? -21.897 -18.575 -48.069 1.00 40.93 ? 156 LYS C CA  1 
ATOM   4842 C C   . LYS C 1 154 ? -21.027 -19.403 -48.999 1.00 43.96 ? 156 LYS C C   1 
ATOM   4843 O O   . LYS C 1 154 ? -21.113 -20.637 -49.005 1.00 45.54 ? 156 LYS C O   1 
ATOM   4844 C CB  . LYS C 1 154 ? -23.217 -18.230 -48.763 1.00 44.63 ? 156 LYS C CB  1 
ATOM   4845 C CG  . LYS C 1 154 ? -24.065 -17.200 -48.030 1.00 48.99 ? 156 LYS C CG  1 
ATOM   4846 C CD  . LYS C 1 154 ? -24.755 -16.232 -48.993 1.00 50.30 ? 156 LYS C CD  1 
ATOM   4847 C CE  . LYS C 1 154 ? -23.758 -15.261 -49.617 1.00 52.20 ? 156 LYS C CE  1 
ATOM   4848 N NZ  . LYS C 1 154 ? -22.852 -14.659 -48.589 1.00 45.48 ? 156 LYS C NZ  1 
ATOM   4849 N N   . GLN C 1 155 ? -20.179 -18.744 -49.780 1.00 42.30 ? 157 GLN C N   1 
ATOM   4850 C CA  . GLN C 1 155 ? -19.395 -19.441 -50.793 1.00 44.21 ? 157 GLN C CA  1 
ATOM   4851 C C   . GLN C 1 155 ? -18.234 -20.225 -50.187 1.00 45.73 ? 157 GLN C C   1 
ATOM   4852 O O   . GLN C 1 155 ? -17.912 -21.321 -50.657 1.00 46.40 ? 157 GLN C O   1 
ATOM   4853 C CB  . GLN C 1 155 ? -18.912 -18.422 -51.817 1.00 49.47 ? 157 GLN C CB  1 
ATOM   4854 C CG  . GLN C 1 155 ? -17.792 -17.546 -51.283 1.00 50.24 ? 157 GLN C CG  1 
ATOM   4855 C CD  . GLN C 1 155 ? -17.040 -16.824 -52.361 1.00 58.55 ? 157 GLN C CD  1 
ATOM   4856 O OE1 . GLN C 1 155 ? -16.939 -15.594 -52.349 1.00 60.49 ? 157 GLN C OE1 1 
ATOM   4857 N NE2 . GLN C 1 155 ? -16.472 -17.580 -53.287 1.00 57.66 ? 157 GLN C NE2 1 
ATOM   4858 N N   . LYS C 1 156 ? -17.588 -19.687 -49.156 1.00 41.57 ? 158 LYS C N   1 
ATOM   4859 C CA  . LYS C 1 156 ? -16.563 -20.427 -48.440 1.00 39.95 ? 158 LYS C CA  1 
ATOM   4860 C C   . LYS C 1 156 ? -17.161 -21.205 -47.276 1.00 35.52 ? 158 LYS C C   1 
ATOM   4861 O O   . LYS C 1 156 ? -16.423 -21.808 -46.490 1.00 36.65 ? 158 LYS C O   1 
ATOM   4862 C CB  . LYS C 1 156 ? -15.454 -19.467 -47.990 1.00 38.74 ? 158 LYS C CB  1 
ATOM   4863 C CG  . LYS C 1 156 ? -14.947 -18.586 -49.156 1.00 44.04 ? 158 LYS C CG  1 
ATOM   4864 C CD  . LYS C 1 156 ? -13.442 -18.248 -49.110 1.00 46.35 ? 158 LYS C CD  1 
ATOM   4865 C CE  . LYS C 1 156 ? -13.197 -16.736 -49.387 1.00 49.21 ? 158 LYS C CE  1 
ATOM   4866 N NZ  . LYS C 1 156 ? -12.052 -16.382 -50.309 1.00 39.83 ? 158 LYS C NZ  1 
ATOM   4867 N N   . ASN C 1 157 ? -18.492 -21.213 -47.174 1.00 36.02 ? 159 ASN C N   1 
ATOM   4868 C CA  . ASN C 1 157 ? -19.227 -21.963 -46.158 1.00 34.91 ? 159 ASN C CA  1 
ATOM   4869 C C   . ASN C 1 157 ? -18.851 -21.515 -44.747 1.00 32.18 ? 159 ASN C C   1 
ATOM   4870 O O   . ASN C 1 157 ? -18.892 -22.299 -43.790 1.00 26.26 ? 159 ASN C O   1 
ATOM   4871 C CB  . ASN C 1 157 ? -19.014 -23.469 -46.335 1.00 33.27 ? 159 ASN C CB  1 
ATOM   4872 C CG  . ASN C 1 157 ? -20.218 -24.267 -45.921 1.00 36.93 ? 159 ASN C CG  1 
ATOM   4873 O OD1 . ASN C 1 157 ? -21.349 -23.845 -46.152 1.00 43.98 ? 159 ASN C OD1 1 
ATOM   4874 N ND2 . ASN C 1 157 ? -19.992 -25.446 -45.347 1.00 44.06 ? 159 ASN C ND2 1 
ATOM   4875 N N   . GLY C 1 158 ? -18.496 -20.245 -44.594 1.00 27.89 ? 160 GLY C N   1 
ATOM   4876 C CA  . GLY C 1 158 ? -18.046 -19.792 -43.296 1.00 24.54 ? 160 GLY C CA  1 
ATOM   4877 C C   . GLY C 1 158 ? -18.501 -18.394 -42.965 1.00 25.70 ? 160 GLY C C   1 
ATOM   4878 O O   . GLY C 1 158 ? -19.599 -17.976 -43.355 1.00 25.77 ? 160 GLY C O   1 
ATOM   4879 N N   . ILE C 1 159 ? -17.655 -17.659 -42.244 1.00 21.13 ? 161 ILE C N   1 
ATOM   4880 C CA  . ILE C 1 159 ? -17.963 -16.308 -41.796 1.00 20.64 ? 161 ILE C CA  1 
ATOM   4881 C C   . ILE C 1 159 ? -16.799 -15.376 -42.104 1.00 18.88 ? 161 ILE C C   1 
ATOM   4882 O O   . ILE C 1 159 ? -15.677 -15.807 -42.379 1.00 17.41 ? 161 ILE C O   1 
ATOM   4883 C CB  . ILE C 1 159 ? -18.345 -16.283 -40.293 1.00 23.68 ? 161 ILE C CB  1 
ATOM   4884 C CG1 . ILE C 1 159 ? -17.145 -16.612 -39.378 1.00 22.54 ? 161 ILE C CG1 1 
ATOM   4885 C CG2 . ILE C 1 159 ? -19.521 -17.215 -40.024 1.00 23.27 ? 161 ILE C CG2 1 
ATOM   4886 C CD1 . ILE C 1 159 ? -16.274 -15.421 -38.953 1.00 22.14 ? 161 ILE C CD1 1 
ATOM   4887 N N   . LYS C 1 160 ? -17.094 -14.076 -42.097 1.00 17.23 ? 162 LYS C N   1 
ATOM   4888 C CA  . LYS C 1 160 ? -16.071 -13.044 -42.213 1.00 15.35 ? 162 LYS C CA  1 
ATOM   4889 C C   . LYS C 1 160 ? -16.420 -11.863 -41.327 1.00 17.82 ? 162 LYS C C   1 
ATOM   4890 O O   . LYS C 1 160 ? -17.573 -11.662 -40.940 1.00 17.27 ? 162 LYS C O   1 
ATOM   4891 C CB  . LYS C 1 160 ? -15.867 -12.536 -43.658 1.00 20.98 ? 162 LYS C CB  1 
ATOM   4892 C CG  . LYS C 1 160 ? -15.488 -13.627 -44.638 1.00 25.27 ? 162 LYS C CG  1 
ATOM   4893 C CD  . LYS C 1 160 ? -14.664 -13.116 -45.820 1.00 33.43 ? 162 LYS C CD  1 
ATOM   4894 C CE  . LYS C 1 160 ? -15.391 -12.102 -46.668 1.00 33.92 ? 162 LYS C CE  1 
ATOM   4895 N NZ  . LYS C 1 160 ? -14.529 -11.712 -47.838 1.00 35.95 ? 162 LYS C NZ  1 
ATOM   4896 N N   . ALA C 1 161 ? -15.396 -11.075 -41.017 1.00 15.10 ? 163 ALA C N   1 
ATOM   4897 C CA  . ALA C 1 161 ? -15.579 -9.854  -40.252 1.00 14.51 ? 163 ALA C CA  1 
ATOM   4898 C C   . ALA C 1 161 ? -14.371 -8.969  -40.483 1.00 15.32 ? 163 ALA C C   1 
ATOM   4899 O O   . ALA C 1 161 ? -13.294 -9.440  -40.862 1.00 14.83 ? 163 ALA C O   1 
ATOM   4900 C CB  . ALA C 1 161 ? -15.750 -10.137 -38.755 1.00 14.43 ? 163 ALA C CB  1 
ATOM   4901 N N   . ASN C 1 162 ? -14.563 -7.672  -40.273 1.00 13.94 ? 164 ASN C N   1 
ATOM   4902 C CA  . ASN C 1 162 ? -13.401 -6.797  -40.220 1.00 13.83 ? 164 ASN C CA  1 
ATOM   4903 C C   . ASN C 1 162 ? -13.692 -5.674  -39.246 1.00 16.09 ? 164 ASN C C   1 
ATOM   4904 O O   . ASN C 1 162 ? -14.827 -5.191  -39.178 1.00 16.40 ? 164 ASN C O   1 
ATOM   4905 C CB  . ASN C 1 162 ? -13.002 -6.245  -41.594 1.00 13.00 ? 164 ASN C CB  1 
ATOM   4906 C CG  . ASN C 1 162 ? -14.057 -5.349  -42.214 1.00 17.06 ? 164 ASN C CG  1 
ATOM   4907 O OD1 . ASN C 1 162 ? -15.101 -5.810  -42.688 1.00 16.81 ? 164 ASN C OD1 1 
ATOM   4908 N ND2 . ASN C 1 162 ? -13.786 -4.050  -42.199 1.00 19.41 ? 164 ASN C ND2 1 
ATOM   4909 N N   . PHE C 1 163 ? -12.671 -5.278  -38.484 1.00 15.69 ? 165 PHE C N   1 
ATOM   4910 C CA  . PHE C 1 163 ? -12.879 -4.371  -37.359 1.00 14.03 ? 165 PHE C CA  1 
ATOM   4911 C C   . PHE C 1 163 ? -11.545 -3.756  -36.970 1.00 15.78 ? 165 PHE C C   1 
ATOM   4912 O O   . PHE C 1 163 ? -10.484 -4.318  -37.242 1.00 16.67 ? 165 PHE C O   1 
ATOM   4913 C CB  . PHE C 1 163 ? -13.487 -5.094  -36.153 1.00 16.31 ? 165 PHE C CB  1 
ATOM   4914 C CG  . PHE C 1 163 ? -12.715 -6.331  -35.715 1.00 14.52 ? 165 PHE C CG  1 
ATOM   4915 C CD1 . PHE C 1 163 ? -12.897 -7.559  -36.347 1.00 13.49 ? 165 PHE C CD1 1 
ATOM   4916 C CD2 . PHE C 1 163 ? -11.801 -6.249  -34.668 1.00 15.04 ? 165 PHE C CD2 1 
ATOM   4917 C CE1 . PHE C 1 163 ? -12.189 -8.686  -35.929 1.00 13.04 ? 165 PHE C CE1 1 
ATOM   4918 C CE2 . PHE C 1 163 ? -11.083 -7.368  -34.246 1.00 12.32 ? 165 PHE C CE2 1 
ATOM   4919 C CZ  . PHE C 1 163 ? -11.279 -8.582  -34.876 1.00 14.23 ? 165 PHE C CZ  1 
ATOM   4920 N N   . LYS C 1 164 ? -11.594 -2.631  -36.310 1.00 19.07 ? 166 LYS C N   1 
ATOM   4921 C CA  . LYS C 1 164 ? -10.413 -1.936  -35.857 1.00 20.31 ? 166 LYS C CA  1 
ATOM   4922 C C   . LYS C 1 164 ? -10.192 -2.128  -34.389 1.00 21.21 ? 166 LYS C C   1 
ATOM   4923 O O   . LYS C 1 164 ? -11.089 -2.026  -33.653 1.00 25.17 ? 166 LYS C O   1 
ATOM   4924 C CB  . LYS C 1 164 ? -10.580 -0.456  -36.085 1.00 21.54 ? 166 LYS C CB  1 
ATOM   4925 C CG  . LYS C 1 164 ? -10.544 -0.110  -37.503 1.00 31.31 ? 166 LYS C CG  1 
ATOM   4926 C CD  . LYS C 1 164 ? -10.357 1.345   -37.728 1.00 38.22 ? 166 LYS C CD  1 
ATOM   4927 C CE  . LYS C 1 164 ? -11.586 1.888   -38.320 1.00 37.84 ? 166 LYS C CE  1 
ATOM   4928 N NZ  . LYS C 1 164 ? -11.335 3.219   -38.948 1.00 28.18 ? 166 LYS C NZ  1 
ATOM   4929 N N   . ILE C 1 165 ? -8.959  -2.344  -33.986 1.00 15.29 ? 167 ILE C N   1 
ATOM   4930 C CA  . ILE C 1 165 ? -8.589  -2.360  -32.577 1.00 12.64 ? 167 ILE C CA  1 
ATOM   4931 C C   . ILE C 1 165 ? -7.664  -1.181  -32.328 1.00 14.95 ? 167 ILE C C   1 
ATOM   4932 O O   . ILE C 1 165 ? -6.807  -0.870  -33.162 1.00 19.18 ? 167 ILE C O   1 
ATOM   4933 C CB  . ILE C 1 165 ? -7.915  -3.679  -32.146 1.00 12.88 ? 167 ILE C CB  1 
ATOM   4934 C CG1 . ILE C 1 165 ? -8.918  -4.835  -32.257 1.00 14.65 ? 167 ILE C CG1 1 
ATOM   4935 C CG2 . ILE C 1 165 ? -7.352  -3.561  -30.740 1.00 14.00 ? 167 ILE C CG2 1 
ATOM   4936 C CD1 . ILE C 1 165 ? -9.955  -4.844  -31.159 1.00 14.76 ? 167 ILE C CD1 1 
ATOM   4937 N N   . ARG C 1 166 ? -7.825  -0.549  -31.170 1.00 13.52 ? 168 ARG C N   1 
ATOM   4938 C CA  . ARG C 1 166 ? -7.092  0.645   -30.779 1.00 17.50 ? 168 ARG C CA  1 
ATOM   4939 C C   . ARG C 1 166 ? -6.193  0.263   -29.608 1.00 16.95 ? 168 ARG C C   1 
ATOM   4940 O O   . ARG C 1 166 ? -6.698  -0.216  -28.590 1.00 16.56 ? 168 ARG C O   1 
ATOM   4941 C CB  . ARG C 1 166 ? -8.088  1.727   -30.365 1.00 19.02 ? 168 ARG C CB  1 
ATOM   4942 C CG  . ARG C 1 166 ? -8.357  2.817   -31.394 1.00 26.26 ? 168 ARG C CG  1 
ATOM   4943 C CD  . ARG C 1 166 ? -9.203  2.328   -32.534 1.00 33.14 ? 168 ARG C CD  1 
ATOM   4944 N NE  . ARG C 1 166 ? -10.097 3.362   -33.051 1.00 37.43 ? 168 ARG C NE  1 
ATOM   4945 C CZ  . ARG C 1 166 ? -11.282 3.102   -33.586 1.00 35.47 ? 168 ARG C CZ  1 
ATOM   4946 N NH1 . ARG C 1 166 ? -11.768 1.870   -33.615 1.00 32.74 ? 168 ARG C NH1 1 
ATOM   4947 N NH2 . ARG C 1 166 ? -11.988 4.098   -34.120 1.00 37.29 ? 168 ARG C NH2 1 
ATOM   4948 N N   . HIS C 1 167 ? -4.873  0.468   -29.741 1.00 15.62 ? 169 HIS C N   1 
ATOM   4949 C CA  . HIS C 1 167 ? -3.914  0.172   -28.674 1.00 15.72 ? 169 HIS C CA  1 
ATOM   4950 C C   . HIS C 1 167 ? -3.350  1.487   -28.157 1.00 18.08 ? 169 HIS C C   1 
ATOM   4951 O O   . HIS C 1 167 ? -2.760  2.252   -28.924 1.00 17.02 ? 169 HIS C O   1 
ATOM   4952 C CB  . HIS C 1 167 ? -2.747  -0.680  -29.173 1.00 15.89 ? 169 HIS C CB  1 
ATOM   4953 C CG  . HIS C 1 167 ? -3.140  -2.042  -29.644 1.00 13.55 ? 169 HIS C CG  1 
ATOM   4954 N ND1 . HIS C 1 167 ? -3.692  -3.001  -28.825 1.00 13.45 ? 169 HIS C ND1 1 
ATOM   4955 C CD2 . HIS C 1 167 ? -3.020  -2.614  -30.867 1.00 16.16 ? 169 HIS C CD2 1 
ATOM   4956 C CE1 . HIS C 1 167 ? -3.926  -4.095  -29.531 1.00 14.04 ? 169 HIS C CE1 1 
ATOM   4957 N NE2 . HIS C 1 167 ? -3.525  -3.888  -30.772 1.00 14.00 ? 169 HIS C NE2 1 
ATOM   4958 N N   . ASN C 1 168 ? -3.465  1.718   -26.858 1.00 18.60 ? 170 ASN C N   1 
ATOM   4959 C CA  . ASN C 1 168 ? -2.949  2.955   -26.278 1.00 18.32 ? 170 ASN C CA  1 
ATOM   4960 C C   . ASN C 1 168 ? -1.428  2.995   -26.386 1.00 22.44 ? 170 ASN C C   1 
ATOM   4961 O O   . ASN C 1 168 ? -0.748  2.019   -26.058 1.00 18.25 ? 170 ASN C O   1 
ATOM   4962 C CB  . ASN C 1 168 ? -3.366  3.042   -24.816 1.00 24.10 ? 170 ASN C CB  1 
ATOM   4963 C CG  . ASN C 1 168 ? -4.843  3.368   -24.645 1.00 24.49 ? 170 ASN C CG  1 
ATOM   4964 O OD1 . ASN C 1 168 ? -5.590  2.571   -24.094 1.00 31.78 ? 170 ASN C OD1 1 
ATOM   4965 N ND2 . ASN C 1 168 ? -5.257  4.539   -25.086 1.00 27.77 ? 170 ASN C ND2 1 
ATOM   4966 N N   . ILE C 1 169 ? -0.895  4.128   -26.826 1.00 18.44 ? 171 ILE C N   1 
ATOM   4967 C CA  . ILE C 1 169 ? 0.546   4.312   -26.957 1.00 21.19 ? 171 ILE C CA  1 
ATOM   4968 C C   . ILE C 1 169 ? 1.086   4.946   -25.682 1.00 25.96 ? 171 ILE C C   1 
ATOM   4969 O O   . ILE C 1 169 ? 0.554   5.956   -25.204 1.00 21.44 ? 171 ILE C O   1 
ATOM   4970 C CB  . ILE C 1 169 ? 0.887   5.182   -28.181 1.00 19.79 ? 171 ILE C CB  1 
ATOM   4971 C CG1 . ILE C 1 169 ? 0.401   4.539   -29.492 1.00 22.12 ? 171 ILE C CG1 1 
ATOM   4972 C CG2 . ILE C 1 169 ? 2.368   5.461   -28.230 1.00 23.98 ? 171 ILE C CG2 1 
ATOM   4973 N N   . GLU C 1 170 ? 2.132   4.346   -25.120 1.00 23.05 ? 172 GLU C N   1 
ATOM   4974 C CA  . GLU C 1 170 ? 2.852   5.000   -24.041 1.00 29.44 ? 172 GLU C CA  1 
ATOM   4975 C C   . GLU C 1 170 ? 3.298   6.359   -24.550 1.00 31.76 ? 172 GLU C C   1 
ATOM   4976 O O   . GLU C 1 170 ? 3.817   6.464   -25.658 1.00 40.85 ? 172 GLU C O   1 
ATOM   4977 C CB  . GLU C 1 170 ? 4.053   4.159   -23.613 1.00 30.37 ? 172 GLU C CB  1 
ATOM   4978 C CG  . GLU C 1 170 ? 3.699   2.899   -22.817 1.00 28.67 ? 172 GLU C CG  1 
ATOM   4979 C CD  . GLU C 1 170 ? 4.910   2.006   -22.565 1.00 34.67 ? 172 GLU C CD  1 
ATOM   4980 O OE1 . GLU C 1 170 ? 5.939   2.201   -23.250 1.00 38.06 ? 172 GLU C OE1 1 
ATOM   4981 O OE2 . GLU C 1 170 ? 4.826   1.096   -21.708 1.00 36.93 ? 172 GLU C OE2 1 
ATOM   4982 N N   . ASP C 1 171 ? 3.027   7.388   -23.765 1.00 30.61 ? 173 ASP C N   1 
ATOM   4983 C CA  . ASP C 1 171 ? 3.338   8.803   -24.005 1.00 35.90 ? 173 ASP C CA  1 
ATOM   4984 C C   . ASP C 1 171 ? 2.509   9.410   -25.134 1.00 29.75 ? 173 ASP C C   1 
ATOM   4985 O O   . ASP C 1 171 ? 2.840   10.487  -25.639 1.00 29.36 ? 173 ASP C O   1 
ATOM   4986 C CB  . ASP C 1 171 ? 4.842   9.096   -24.242 1.00 37.00 ? 173 ASP C CB  1 
ATOM   4987 C CG  . ASP C 1 171 ? 5.375   8.676   -25.618 1.00 42.41 ? 173 ASP C CG  1 
ATOM   4988 O OD1 . ASP C 1 171 ? 4.616   8.539   -26.602 1.00 43.88 ? 173 ASP C OD1 1 
ATOM   4989 O OD2 . ASP C 1 171 ? 6.606   8.459   -25.711 1.00 45.37 ? 173 ASP C OD2 1 
ATOM   4990 N N   . GLY C 1 172 ? 1.415   8.789   -25.547 1.00 25.78 ? 174 GLY C N   1 
ATOM   4991 C CA  . GLY C 1 172 ? 0.646   9.541   -26.506 1.00 29.20 ? 174 GLY C CA  1 
ATOM   4992 C C   . GLY C 1 172 ? -0.613  8.952   -27.072 1.00 28.74 ? 174 GLY C C   1 
ATOM   4993 O O   . GLY C 1 172 ? -1.610  8.801   -26.374 1.00 40.30 ? 174 GLY C O   1 
ATOM   4994 N N   . GLY C 1 173 ? -0.611  8.649   -28.342 1.00 28.63 ? 175 GLY C N   1 
ATOM   4995 C CA  . GLY C 1 173 ? -1.867  8.495   -29.049 1.00 31.16 ? 175 GLY C CA  1 
ATOM   4996 C C   . GLY C 1 173 ? -2.513  7.141   -28.869 1.00 20.32 ? 175 GLY C C   1 
ATOM   4997 O O   . GLY C 1 173 ? -2.469  6.520   -27.798 1.00 19.01 ? 175 GLY C O   1 
ATOM   4998 N N   . VAL C 1 174 ? -3.135  6.685   -29.942 1.00 19.51 ? 176 VAL C N   1 
ATOM   4999 C CA  . VAL C 1 174 ? -3.582  5.314   -30.075 1.00 18.95 ? 176 VAL C CA  1 
ATOM   5000 C C   . VAL C 1 174 ? -2.966  4.749   -31.345 1.00 20.54 ? 176 VAL C C   1 
ATOM   5001 O O   . VAL C 1 174 ? -2.820  5.465   -32.342 1.00 18.64 ? 176 VAL C O   1 
ATOM   5002 C CB  . VAL C 1 174 ? -5.119  5.224   -30.117 1.00 21.70 ? 176 VAL C CB  1 
ATOM   5003 C CG1 . VAL C 1 174 ? -5.479  3.845   -30.360 1.00 27.47 ? 176 VAL C CG1 1 
ATOM   5004 C CG2 . VAL C 1 174 ? -5.705  5.672   -28.782 1.00 23.27 ? 176 VAL C CG2 1 
ATOM   5005 N N   . GLN C 1 175 ? -2.585  3.475   -31.289 1.00 18.35 ? 177 GLN C N   1 
ATOM   5006 C CA  . GLN C 1 175 ? -2.055  2.742   -32.427 1.00 14.50 ? 177 GLN C CA  1 
ATOM   5007 C C   . GLN C 1 175 ? -3.172  1.868   -32.984 1.00 16.95 ? 177 GLN C C   1 
ATOM   5008 O O   . GLN C 1 175 ? -3.694  1.007   -32.271 1.00 15.68 ? 177 GLN C O   1 
ATOM   5009 C CB  . GLN C 1 175 ? -0.858  1.898   -31.990 1.00 17.22 ? 177 GLN C CB  1 
ATOM   5010 C CG  . GLN C 1 175 ? -0.434  0.811   -32.964 1.00 17.73 ? 177 GLN C CG  1 
ATOM   5011 C CD  . GLN C 1 175 ? 0.320   1.427   -34.129 1.00 15.95 ? 177 GLN C CD  1 
ATOM   5012 O OE1 . GLN C 1 175 ? 1.425   1.947   -33.960 1.00 18.63 ? 177 GLN C OE1 1 
ATOM   5013 N NE2 . GLN C 1 175 ? -0.255  1.334   -35.328 1.00 19.11 ? 177 GLN C NE2 1 
ATOM   5014 N N   . LEU C 1 176 ? -3.543  2.104   -34.240 1.00 17.07 ? 178 LEU C N   1 
ATOM   5015 C CA  . LEU C 1 176 ? -4.601  1.342   -34.895 1.00 15.94 ? 178 LEU C CA  1 
ATOM   5016 C C   . LEU C 1 176 ? -4.097  -0.007  -35.394 1.00 17.17 ? 178 LEU C C   1 
ATOM   5017 O O   . LEU C 1 176 ? -3.006  -0.108  -35.970 1.00 16.53 ? 178 LEU C O   1 
ATOM   5018 C CB  . LEU C 1 176 ? -5.163  2.118   -36.086 1.00 20.02 ? 178 LEU C CB  1 
ATOM   5019 C CG  . LEU C 1 176 ? -6.516  2.759   -35.807 1.00 31.06 ? 178 LEU C CG  1 
ATOM   5020 C CD1 . LEU C 1 176 ? -7.521  1.654   -35.550 1.00 29.79 ? 178 LEU C CD1 1 
ATOM   5021 C CD2 . LEU C 1 176 ? -6.420  3.696   -34.625 1.00 30.18 ? 178 LEU C CD2 1 
ATOM   5022 N N   . ALA C 1 177 ? -4.920  -1.035  -35.188 1.00 14.17 ? 179 ALA C N   1 
ATOM   5023 C CA  . ALA C 1 177 ? -4.677  -2.390  -35.673 1.00 14.39 ? 179 ALA C CA  1 
ATOM   5024 C C   . ALA C 1 177 ? -5.929  -2.791  -36.454 1.00 14.14 ? 179 ALA C C   1 
ATOM   5025 O O   . ALA C 1 177 ? -6.966  -3.132  -35.870 1.00 14.29 ? 179 ALA C O   1 
ATOM   5026 C CB  . ALA C 1 177 ? -4.375  -3.351  -34.518 1.00 12.54 ? 179 ALA C CB  1 
ATOM   5027 N N   . ASP C 1 178 ? -5.827  -2.762  -37.777 1.00 13.22 ? 180 ASP C N   1 
ATOM   5028 C CA  . ASP C 1 178 ? -6.980  -2.941  -38.653 1.00 15.69 ? 180 ASP C CA  1 
ATOM   5029 C C   . ASP C 1 178 ? -7.075  -4.420  -39.025 1.00 15.32 ? 180 ASP C C   1 
ATOM   5030 O O   . ASP C 1 178 ? -6.184  -4.950  -39.697 1.00 13.40 ? 180 ASP C O   1 
ATOM   5031 C CB  . ASP C 1 178 ? -6.811  -2.047  -39.876 1.00 16.81 ? 180 ASP C CB  1 
ATOM   5032 C CG  . ASP C 1 178 ? -8.060  -1.962  -40.730 1.00 21.39 ? 180 ASP C CG  1 
ATOM   5033 O OD1 . ASP C 1 178 ? -9.125  -2.409  -40.274 1.00 19.78 ? 180 ASP C OD1 1 
ATOM   5034 O OD2 . ASP C 1 178 ? -7.962  -1.448  -41.867 1.00 19.37 ? 180 ASP C OD2 1 
ATOM   5035 N N   . HIS C 1 179 ? -8.143  -5.084  -38.577 1.00 13.05 ? 181 HIS C N   1 
ATOM   5036 C CA  . HIS C 1 179 ? -8.297  -6.534  -38.657 1.00 14.23 ? 181 HIS C CA  1 
ATOM   5037 C C   . HIS C 1 179 ? -9.215  -6.925  -39.812 1.00 14.28 ? 181 HIS C C   1 
ATOM   5038 O O   . HIS C 1 179 ? -10.334 -6.422  -39.914 1.00 13.28 ? 181 HIS C O   1 
ATOM   5039 C CB  . HIS C 1 179 ? -8.914  -7.078  -37.368 1.00 13.92 ? 181 HIS C CB  1 
ATOM   5040 C CG  . HIS C 1 179 ? -7.987  -7.112  -36.190 1.00 12.88 ? 181 HIS C CG  1 
ATOM   5041 N ND1 . HIS C 1 179 ? -7.390  -5.975  -35.675 1.00 12.98 ? 181 HIS C ND1 1 
ATOM   5042 C CD2 . HIS C 1 179 ? -7.644  -8.124  -35.359 1.00 11.79 ? 181 HIS C CD2 1 
ATOM   5043 C CE1 . HIS C 1 179 ? -6.685  -6.301  -34.603 1.00 13.78 ? 181 HIS C CE1 1 
ATOM   5044 N NE2 . HIS C 1 179 ? -6.831  -7.595  -34.383 1.00 11.39 ? 181 HIS C NE2 1 
ATOM   5045 N N   . TYR C 1 180 ? -8.777  -7.877  -40.623 1.00 9.91  ? 182 TYR C N   1 
ATOM   5046 C CA  . TYR C 1 180 ? -9.625  -8.537  -41.608 1.00 12.23 ? 182 TYR C CA  1 
ATOM   5047 C C   . TYR C 1 180 ? -9.595  -10.026 -41.312 1.00 14.46 ? 182 TYR C C   1 
ATOM   5048 O O   . TYR C 1 180 ? -8.518  -10.603 -41.160 1.00 13.81 ? 182 TYR C O   1 
ATOM   5049 C CB  . TYR C 1 180 ? -9.149  -8.240  -43.040 1.00 14.79 ? 182 TYR C CB  1 
ATOM   5050 C CG  . TYR C 1 180 ? -9.159  -6.755  -43.292 1.00 13.51 ? 182 TYR C CG  1 
ATOM   5051 C CD1 . TYR C 1 180 ? -8.103  -5.952  -42.865 1.00 13.91 ? 182 TYR C CD1 1 
ATOM   5052 C CD2 . TYR C 1 180 ? -10.251 -6.145  -43.899 1.00 14.03 ? 182 TYR C CD2 1 
ATOM   5053 C CE1 . TYR C 1 180 ? -8.120  -4.594  -43.052 1.00 15.41 ? 182 TYR C CE1 1 
ATOM   5054 C CE2 . TYR C 1 180 ? -10.280 -4.770  -44.096 1.00 14.63 ? 182 TYR C CE2 1 
ATOM   5055 C CZ  . TYR C 1 180 ? -9.205  -4.005  -43.682 1.00 18.53 ? 182 TYR C CZ  1 
ATOM   5056 O OH  . TYR C 1 180 ? -9.220  -2.644  -43.865 1.00 19.68 ? 182 TYR C OH  1 
ATOM   5057 N N   . GLN C 1 181 ? -10.769 -10.645 -41.245 1.00 14.64 ? 183 GLN C N   1 
ATOM   5058 C CA  . GLN C 1 181 ? -10.897 -12.012 -40.759 1.00 13.09 ? 183 GLN C CA  1 
ATOM   5059 C C   . GLN C 1 181 ? -11.776 -12.825 -41.695 1.00 15.69 ? 183 GLN C C   1 
ATOM   5060 O O   . GLN C 1 181 ? -12.774 -12.315 -42.215 1.00 15.36 ? 183 GLN C O   1 
ATOM   5061 C CB  . GLN C 1 181 ? -11.508 -12.006 -39.341 1.00 12.89 ? 183 GLN C CB  1 
ATOM   5062 C CG  . GLN C 1 181 ? -11.794 -13.385 -38.761 1.00 12.44 ? 183 GLN C CG  1 
ATOM   5063 C CD  . GLN C 1 181 ? -12.359 -13.319 -37.352 1.00 13.46 ? 183 GLN C CD  1 
ATOM   5064 O OE1 . GLN C 1 181 ? -12.280 -12.280 -36.679 1.00 11.31 ? 183 GLN C OE1 1 
ATOM   5065 N NE2 . GLN C 1 181 ? -12.937 -14.438 -36.894 1.00 13.59 ? 183 GLN C NE2 1 
ATOM   5066 N N   . GLN C 1 182 ? -11.424 -14.100 -41.889 1.00 14.39 ? 184 GLN C N   1 
ATOM   5067 C CA  . GLN C 1 182 ? -12.334 -15.045 -42.525 1.00 16.62 ? 184 GLN C CA  1 
ATOM   5068 C C   . GLN C 1 182 ? -12.150 -16.414 -41.887 1.00 16.33 ? 184 GLN C C   1 
ATOM   5069 O O   . GLN C 1 182 ? -11.018 -16.826 -41.634 1.00 14.72 ? 184 GLN C O   1 
ATOM   5070 C CB  . GLN C 1 182 ? -12.097 -15.180 -44.045 1.00 22.68 ? 184 GLN C CB  1 
ATOM   5071 C CG  . GLN C 1 182 ? -10.665 -15.465 -44.430 1.00 23.55 ? 184 GLN C CG  1 
ATOM   5072 C CD  . GLN C 1 182 ? -10.517 -15.882 -45.898 1.00 35.30 ? 184 GLN C CD  1 
ATOM   5073 O OE1 . GLN C 1 182 ? -11.483 -15.851 -46.667 1.00 38.70 ? 184 GLN C OE1 1 
ATOM   5074 N NE2 . GLN C 1 182 ? -9.315  -16.326 -46.272 1.00 33.82 ? 184 GLN C NE2 1 
ATOM   5075 N N   . ASN C 1 183 ? -13.260 -17.121 -41.655 1.00 16.33 ? 185 ASN C N   1 
ATOM   5076 C CA  . ASN C 1 183 ? -13.251 -18.452 -41.049 1.00 15.42 ? 185 ASN C CA  1 
ATOM   5077 C C   . ASN C 1 183 ? -13.961 -19.442 -41.959 1.00 16.49 ? 185 ASN C C   1 
ATOM   5078 O O   . ASN C 1 183 ? -15.000 -19.122 -42.538 1.00 18.94 ? 185 ASN C O   1 
ATOM   5079 C CB  . ASN C 1 183 ? -13.952 -18.484 -39.677 1.00 13.28 ? 185 ASN C CB  1 
ATOM   5080 C CG  . ASN C 1 183 ? -13.220 -17.686 -38.592 1.00 15.80 ? 185 ASN C CG  1 
ATOM   5081 O OD1 . ASN C 1 183 ? -12.647 -16.644 -38.848 1.00 19.38 ? 185 ASN C OD1 1 
ATOM   5082 N ND2 . ASN C 1 183 ? -13.293 -18.174 -37.360 1.00 17.90 ? 185 ASN C ND2 1 
ATOM   5083 N N   . THR C 1 184 ? -13.419 -20.656 -42.059 1.00 16.57 ? 186 THR C N   1 
ATOM   5084 C CA  . THR C 1 184 ? -13.988 -21.692 -42.914 1.00 19.34 ? 186 THR C CA  1 
ATOM   5085 C C   . THR C 1 184 ? -13.926 -23.024 -42.176 1.00 18.23 ? 186 THR C C   1 
ATOM   5086 O O   . THR C 1 184 ? -12.943 -23.298 -41.479 1.00 20.06 ? 186 THR C O   1 
ATOM   5087 C CB  . THR C 1 184 ? -13.241 -21.817 -44.256 1.00 24.73 ? 186 THR C CB  1 
ATOM   5088 O OG1 . THR C 1 184 ? -11.904 -22.253 -44.013 1.00 28.16 ? 186 THR C OG1 1 
ATOM   5089 C CG2 . THR C 1 184 ? -13.190 -20.493 -44.991 1.00 27.07 ? 186 THR C CG2 1 
ATOM   5090 N N   . PRO C 1 185 ? -14.941 -23.871 -42.309 1.00 19.92 ? 187 PRO C N   1 
ATOM   5091 C CA  . PRO C 1 185 ? -14.929 -25.144 -41.577 1.00 19.95 ? 187 PRO C CA  1 
ATOM   5092 C C   . PRO C 1 185 ? -13.842 -26.078 -42.082 1.00 20.19 ? 187 PRO C C   1 
ATOM   5093 O O   . PRO C 1 185 ? -13.434 -26.041 -43.244 1.00 24.62 ? 187 PRO C O   1 
ATOM   5094 C CB  . PRO C 1 185 ? -16.324 -25.732 -41.824 1.00 23.72 ? 187 PRO C CB  1 
ATOM   5095 C CG  . PRO C 1 185 ? -16.943 -24.930 -42.892 1.00 26.90 ? 187 PRO C CG  1 
ATOM   5096 C CD  . PRO C 1 185 ? -16.188 -23.647 -43.057 1.00 23.89 ? 187 PRO C CD  1 
ATOM   5097 N N   . ILE C 1 186 ? -13.355 -26.916 -41.174 1.00 17.29 ? 188 ILE C N   1 
ATOM   5098 C CA  . ILE C 1 186 ? -12.367 -27.915 -41.561 1.00 23.92 ? 188 ILE C CA  1 
ATOM   5099 C C   . ILE C 1 186 ? -13.051 -29.130 -42.172 1.00 24.48 ? 188 ILE C C   1 
ATOM   5100 O O   . ILE C 1 186 ? -12.594 -29.668 -43.185 1.00 29.61 ? 188 ILE C O   1 
ATOM   5101 C CB  . ILE C 1 186 ? -11.503 -28.299 -40.346 1.00 23.58 ? 188 ILE C CB  1 
ATOM   5102 C CG1 . ILE C 1 186 ? -10.594 -27.129 -39.964 1.00 19.22 ? 188 ILE C CG1 1 
ATOM   5103 C CG2 . ILE C 1 186 ? -10.641 -29.519 -40.655 1.00 24.00 ? 188 ILE C CG2 1 
ATOM   5104 C CD1 . ILE C 1 186 ? -9.840  -27.354 -38.650 1.00 19.82 ? 188 ILE C CD1 1 
ATOM   5105 N N   . GLY C 1 187 ? -14.157 -29.570 -41.583 1.00 27.65 ? 189 GLY C N   1 
ATOM   5106 C CA  . GLY C 1 187 ? -14.821 -30.770 -42.037 1.00 34.87 ? 189 GLY C CA  1 
ATOM   5107 C C   . GLY C 1 187 ? -15.679 -30.550 -43.270 1.00 42.61 ? 189 GLY C C   1 
ATOM   5108 O O   . GLY C 1 187 ? -15.709 -29.481 -43.882 1.00 38.30 ? 189 GLY C O   1 
ATOM   5109 N N   . ASP C 1 188 ? -16.391 -31.613 -43.643 1.00 46.75 ? 190 ASP C N   1 
ATOM   5110 C CA  . ASP C 1 188 ? -17.360 -31.559 -44.724 1.00 46.73 ? 190 ASP C CA  1 
ATOM   5111 C C   . ASP C 1 188 ? -18.791 -31.450 -44.220 1.00 47.07 ? 190 ASP C C   1 
ATOM   5112 O O   . ASP C 1 188 ? -19.696 -31.219 -45.026 1.00 48.40 ? 190 ASP C O   1 
ATOM   5113 C CB  . ASP C 1 188 ? -17.238 -32.805 -45.611 1.00 50.59 ? 190 ASP C CB  1 
ATOM   5114 C CG  . ASP C 1 188 ? -15.845 -32.980 -46.183 1.00 57.15 ? 190 ASP C CG  1 
ATOM   5115 O OD1 . ASP C 1 188 ? -15.485 -32.229 -47.116 1.00 55.00 ? 190 ASP C OD1 1 
ATOM   5116 O OD2 . ASP C 1 188 ? -15.117 -33.882 -45.710 1.00 59.08 ? 190 ASP C OD2 1 
ATOM   5117 N N   . GLY C 1 189 ? -19.012 -31.610 -42.915 1.00 49.08 ? 191 GLY C N   1 
ATOM   5118 C CA  . GLY C 1 189 ? -20.338 -31.671 -42.355 1.00 48.29 ? 191 GLY C CA  1 
ATOM   5119 C C   . GLY C 1 189 ? -21.108 -30.377 -42.491 1.00 45.89 ? 191 GLY C C   1 
ATOM   5120 O O   . GLY C 1 189 ? -20.542 -29.316 -42.771 1.00 45.91 ? 191 GLY C O   1 
ATOM   5121 N N   . PRO C 1 190 ? -22.433 -30.457 -42.332 1.00 47.24 ? 192 PRO C N   1 
ATOM   5122 C CA  . PRO C 1 190 ? -23.260 -29.247 -42.341 1.00 43.05 ? 192 PRO C CA  1 
ATOM   5123 C C   . PRO C 1 190 ? -22.785 -28.238 -41.307 1.00 42.39 ? 192 PRO C C   1 
ATOM   5124 O O   . PRO C 1 190 ? -22.208 -28.592 -40.277 1.00 39.59 ? 192 PRO C O   1 
ATOM   5125 C CB  . PRO C 1 190 ? -24.661 -29.782 -41.997 1.00 44.95 ? 192 PRO C CB  1 
ATOM   5126 C CG  . PRO C 1 190 ? -24.424 -31.288 -41.699 1.00 47.04 ? 192 PRO C CG  1 
ATOM   5127 C CD  . PRO C 1 190 ? -23.296 -31.613 -42.594 1.00 47.70 ? 192 PRO C CD  1 
ATOM   5128 N N   . VAL C 1 191 ? -23.059 -26.969 -41.585 1.00 39.97 ? 193 VAL C N   1 
ATOM   5129 C CA  . VAL C 1 191 ? -22.573 -25.867 -40.765 1.00 36.96 ? 193 VAL C CA  1 
ATOM   5130 C C   . VAL C 1 191 ? -23.601 -24.745 -40.782 1.00 35.62 ? 193 VAL C C   1 
ATOM   5131 O O   . VAL C 1 191 ? -24.155 -24.414 -41.835 1.00 35.81 ? 193 VAL C O   1 
ATOM   5132 C CB  . VAL C 1 191 ? -21.194 -25.395 -41.262 1.00 37.82 ? 193 VAL C CB  1 
ATOM   5133 C CG1 . VAL C 1 191 ? -20.989 -23.958 -40.949 1.00 39.37 ? 193 VAL C CG1 1 
ATOM   5134 C CG2 . VAL C 1 191 ? -20.086 -26.220 -40.586 1.00 32.36 ? 193 VAL C CG2 1 
ATOM   5135 N N   . LEU C 1 192 ? -23.859 -24.171 -39.605 1.00 34.98 ? 194 LEU C N   1 
ATOM   5136 C CA  . LEU C 1 192 ? -24.781 -23.048 -39.468 1.00 33.60 ? 194 LEU C CA  1 
ATOM   5137 C C   . LEU C 1 192 ? -24.155 -21.779 -40.035 1.00 36.25 ? 194 LEU C C   1 
ATOM   5138 O O   . LEU C 1 192 ? -23.107 -21.328 -39.556 1.00 34.06 ? 194 LEU C O   1 
ATOM   5139 C CB  . LEU C 1 192 ? -25.138 -22.848 -37.998 1.00 29.38 ? 194 LEU C CB  1 
ATOM   5140 C CG  . LEU C 1 192 ? -25.686 -24.046 -37.221 1.00 34.17 ? 194 LEU C CG  1 
ATOM   5141 C CD1 . LEU C 1 192 ? -26.220 -23.611 -35.873 1.00 30.78 ? 194 LEU C CD1 1 
ATOM   5142 C CD2 . LEU C 1 192 ? -26.797 -24.710 -38.028 1.00 33.71 ? 194 LEU C CD2 1 
ATOM   5143 N N   . LEU C 1 193 ? -24.797 -21.189 -41.047 1.00 34.83 ? 195 LEU C N   1 
ATOM   5144 C CA  . LEU C 1 193 ? -24.343 -19.909 -41.573 1.00 30.43 ? 195 LEU C CA  1 
ATOM   5145 C C   . LEU C 1 193 ? -25.221 -18.797 -41.031 1.00 35.34 ? 195 LEU C C   1 
ATOM   5146 O O   . LEU C 1 193 ? -26.432 -18.784 -41.304 1.00 31.28 ? 195 LEU C O   1 
ATOM   5147 C CB  . LEU C 1 193 ? -24.360 -19.905 -43.094 1.00 33.70 ? 195 LEU C CB  1 
ATOM   5148 C CG  . LEU C 1 193 ? -23.496 -21.002 -43.706 1.00 36.30 ? 195 LEU C CG  1 
ATOM   5149 C CD1 . LEU C 1 193 ? -23.605 -20.990 -45.219 1.00 34.11 ? 195 LEU C CD1 1 
ATOM   5150 C CD2 . LEU C 1 193 ? -22.048 -20.824 -43.254 1.00 33.66 ? 195 LEU C CD2 1 
ATOM   5151 N N   . PRO C 1 194 ? -24.667 -17.842 -40.294 1.00 31.56 ? 196 PRO C N   1 
ATOM   5152 C CA  . PRO C 1 194 ? -25.507 -16.935 -39.511 1.00 30.29 ? 196 PRO C CA  1 
ATOM   5153 C C   . PRO C 1 194 ? -26.019 -15.763 -40.327 1.00 31.56 ? 196 PRO C C   1 
ATOM   5154 O O   . PRO C 1 194 ? -25.424 -15.357 -41.327 1.00 30.08 ? 196 PRO C O   1 
ATOM   5155 C CB  . PRO C 1 194 ? -24.546 -16.448 -38.421 1.00 31.09 ? 196 PRO C CB  1 
ATOM   5156 C CG  . PRO C 1 194 ? -23.231 -16.380 -39.162 1.00 28.36 ? 196 PRO C CG  1 
ATOM   5157 C CD  . PRO C 1 194 ? -23.234 -17.645 -40.000 1.00 30.80 ? 196 PRO C CD  1 
ATOM   5158 N N   . ASP C 1 195 ? -27.156 -15.230 -39.883 1.00 34.37 ? 197 ASP C N   1 
ATOM   5159 C CA  . ASP C 1 195 ? -27.517 -13.858 -40.198 1.00 35.25 ? 197 ASP C CA  1 
ATOM   5160 C C   . ASP C 1 195 ? -26.486 -12.927 -39.566 1.00 33.20 ? 197 ASP C C   1 
ATOM   5161 O O   . ASP C 1 195 ? -25.795 -13.291 -38.611 1.00 30.91 ? 197 ASP C O   1 
ATOM   5162 C CB  . ASP C 1 195 ? -28.910 -13.526 -39.656 1.00 34.26 ? 197 ASP C CB  1 
ATOM   5163 C CG  . ASP C 1 195 ? -30.035 -14.189 -40.449 1.00 42.91 ? 197 ASP C CG  1 
ATOM   5164 O OD1 . ASP C 1 195 ? -29.750 -14.974 -41.377 1.00 44.82 ? 197 ASP C OD1 1 
ATOM   5165 O OD2 . ASP C 1 195 ? -31.215 -13.957 -40.106 1.00 42.85 ? 197 ASP C OD2 1 
ATOM   5166 N N   . ASN C 1 196 ? -26.380 -11.714 -40.107 1.00 30.79 ? 198 ASN C N   1 
ATOM   5167 C CA  . ASN C 1 196 ? -25.455 -10.744 -39.539 1.00 25.12 ? 198 ASN C CA  1 
ATOM   5168 C C   . ASN C 1 196 ? -25.763 -10.534 -38.060 1.00 29.54 ? 198 ASN C C   1 
ATOM   5169 O O   . ASN C 1 196 ? -26.927 -10.409 -37.669 1.00 27.49 ? 198 ASN C O   1 
ATOM   5170 C CB  . ASN C 1 196 ? -25.553 -9.410  -40.275 1.00 29.81 ? 198 ASN C CB  1 
ATOM   5171 C CG  . ASN C 1 196 ? -25.195 -9.515  -41.741 1.00 31.55 ? 198 ASN C CG  1 
ATOM   5172 O OD1 . ASN C 1 196 ? -24.769 -10.569 -42.224 1.00 32.20 ? 198 ASN C OD1 1 
ATOM   5173 N ND2 . ASN C 1 196 ? -25.334 -8.401  -42.457 1.00 29.94 ? 198 ASN C ND2 1 
ATOM   5174 N N   . HIS C 1 197 ? -24.717 -10.504 -37.230 1.00 25.96 ? 199 HIS C N   1 
ATOM   5175 C CA  . HIS C 1 197 ? -24.883 -10.234 -35.804 1.00 24.95 ? 199 HIS C CA  1 
ATOM   5176 C C   . HIS C 1 197 ? -23.562 -9.720  -35.241 1.00 20.79 ? 199 HIS C C   1 
ATOM   5177 O O   . HIS C 1 197 ? -22.548 -9.667  -35.940 1.00 19.78 ? 199 HIS C O   1 
ATOM   5178 C CB  . HIS C 1 197 ? -25.360 -11.477 -35.045 1.00 24.80 ? 199 HIS C CB  1 
ATOM   5179 C CG  . HIS C 1 197 ? -24.376 -12.604 -35.050 1.00 23.46 ? 199 HIS C CG  1 
ATOM   5180 N ND1 . HIS C 1 197 ? -24.181 -13.417 -36.146 1.00 28.81 ? 199 HIS C ND1 1 
ATOM   5181 C CD2 . HIS C 1 197 ? -23.526 -13.050 -34.095 1.00 19.91 ? 199 HIS C CD2 1 
ATOM   5182 C CE1 . HIS C 1 197 ? -23.253 -14.318 -35.863 1.00 24.28 ? 199 HIS C CE1 1 
ATOM   5183 N NE2 . HIS C 1 197 ? -22.838 -14.114 -34.625 1.00 24.17 ? 199 HIS C NE2 1 
ATOM   5184 N N   . TYR C 1 198 ? -23.580 -9.359  -33.958 1.00 18.21 ? 200 TYR C N   1 
ATOM   5185 C CA  . TYR C 1 198 ? -22.406 -8.840  -33.272 1.00 19.62 ? 200 TYR C CA  1 
ATOM   5186 C C   . TYR C 1 198 ? -21.882 -9.828  -32.241 1.00 17.58 ? 200 TYR C C   1 
ATOM   5187 O O   . TYR C 1 198 ? -22.641 -10.611 -31.658 1.00 19.39 ? 200 TYR C O   1 
ATOM   5188 C CB  . TYR C 1 198 ? -22.712 -7.514  -32.559 1.00 21.72 ? 200 TYR C CB  1 
ATOM   5189 C CG  . TYR C 1 198 ? -22.945 -6.338  -33.480 1.00 27.17 ? 200 TYR C CG  1 
ATOM   5190 C CD1 . TYR C 1 198 ? -21.872 -5.628  -34.018 1.00 27.87 ? 200 TYR C CD1 1 
ATOM   5191 C CD2 . TYR C 1 198 ? -24.232 -5.933  -33.810 1.00 30.00 ? 200 TYR C CD2 1 
ATOM   5192 C CE1 . TYR C 1 198 ? -22.080 -4.548  -34.862 1.00 29.57 ? 200 TYR C CE1 1 
ATOM   5193 C CE2 . TYR C 1 198 ? -24.447 -4.853  -34.651 1.00 33.45 ? 200 TYR C CE2 1 
ATOM   5194 C CZ  . TYR C 1 198 ? -23.369 -4.166  -35.172 1.00 30.52 ? 200 TYR C CZ  1 
ATOM   5195 O OH  . TYR C 1 198 ? -23.591 -3.100  -36.017 1.00 38.36 ? 200 TYR C OH  1 
ATOM   5196 N N   . LEU C 1 199 ? -20.571 -9.760  -32.008 1.00 17.18 ? 201 LEU C N   1 
ATOM   5197 C CA  . LEU C 1 199 ? -19.923 -10.367 -30.851 1.00 16.75 ? 201 LEU C CA  1 
ATOM   5198 C C   . LEU C 1 199 ? -19.365 -9.232  -30.006 1.00 14.67 ? 201 LEU C C   1 
ATOM   5199 O O   . LEU C 1 199 ? -18.650 -8.368  -30.525 1.00 16.89 ? 201 LEU C O   1 
ATOM   5200 C CB  . LEU C 1 199 ? -18.789 -11.319 -31.257 1.00 18.22 ? 201 LEU C CB  1 
ATOM   5201 C CG  . LEU C 1 199 ? -19.154 -12.578 -32.061 1.00 17.61 ? 201 LEU C CG  1 
ATOM   5202 C CD1 . LEU C 1 199 ? -17.904 -13.410 -32.331 1.00 18.71 ? 201 LEU C CD1 1 
ATOM   5203 C CD2 . LEU C 1 199 ? -20.216 -13.414 -31.381 1.00 20.23 ? 201 LEU C CD2 1 
ATOM   5204 N N   . PHE C 1 200 ? -19.713 -9.211  -28.724 1.00 14.12 ? 202 PHE C N   1 
ATOM   5205 C CA  . PHE C 1 200 ? -19.282 -8.151  -27.820 1.00 16.27 ? 202 PHE C CA  1 
ATOM   5206 C C   . PHE C 1 200 ? -18.388 -8.741  -26.742 1.00 15.10 ? 202 PHE C C   1 
ATOM   5207 O O   . PHE C 1 200 ? -18.766 -9.720  -26.092 1.00 16.89 ? 202 PHE C O   1 
ATOM   5208 C CB  . PHE C 1 200 ? -20.480 -7.446  -27.191 1.00 17.83 ? 202 PHE C CB  1 
ATOM   5209 C CG  . PHE C 1 200 ? -21.359 -6.732  -28.187 1.00 19.22 ? 202 PHE C CG  1 
ATOM   5210 C CD1 . PHE C 1 200 ? -20.836 -5.719  -28.975 1.00 20.09 ? 202 PHE C CD1 1 
ATOM   5211 C CD2 . PHE C 1 200 ? -22.717 -7.008  -28.273 1.00 21.52 ? 202 PHE C CD2 1 
ATOM   5212 C CE1 . PHE C 1 200 ? -21.644 -5.019  -29.864 1.00 24.51 ? 202 PHE C CE1 1 
ATOM   5213 C CE2 . PHE C 1 200 ? -23.529 -6.296  -29.158 1.00 22.67 ? 202 PHE C CE2 1 
ATOM   5214 C CZ  . PHE C 1 200 ? -22.983 -5.305  -29.946 1.00 21.82 ? 202 PHE C CZ  1 
ATOM   5215 N N   . THR C 1 201 ? -17.210 -8.145  -26.557 1.00 13.87 ? 203 THR C N   1 
ATOM   5216 C CA  . THR C 1 201 ? -16.155 -8.707  -25.721 1.00 13.56 ? 203 THR C CA  1 
ATOM   5217 C C   . THR C 1 201 ? -15.693 -7.692  -24.693 1.00 14.27 ? 203 THR C C   1 
ATOM   5218 O O   . THR C 1 201 ? -15.561 -6.507  -24.999 1.00 13.31 ? 203 THR C O   1 
ATOM   5219 C CB  . THR C 1 201 ? -14.940 -9.129  -26.574 1.00 14.60 ? 203 THR C CB  1 
ATOM   5220 O OG1 . THR C 1 201 ? -15.374 -10.017 -27.616 1.00 15.40 ? 203 THR C OG1 1 
ATOM   5221 C CG2 . THR C 1 201 ? -13.884 -9.838  -25.710 1.00 13.51 ? 203 THR C CG2 1 
ATOM   5222 N N   . THR C 1 202 ? -15.408 -8.181  -23.488 1.00 13.33 ? 204 THR C N   1 
ATOM   5223 C CA  . THR C 1 202 ? -14.795 -7.398  -22.424 1.00 13.00 ? 204 THR C CA  1 
ATOM   5224 C C   . THR C 1 202 ? -13.548 -8.143  -21.967 1.00 16.00 ? 204 THR C C   1 
ATOM   5225 O O   . THR C 1 202 ? -13.652 -9.270  -21.486 1.00 15.31 ? 204 THR C O   1 
ATOM   5226 C CB  . THR C 1 202 ? -15.769 -7.225  -21.266 1.00 13.55 ? 204 THR C CB  1 
ATOM   5227 O OG1 . THR C 1 202 ? -16.912 -6.519  -21.746 1.00 14.42 ? 204 THR C OG1 1 
ATOM   5228 C CG2 . THR C 1 202 ? -15.105 -6.411  -20.142 1.00 12.86 ? 204 THR C CG2 1 
ATOM   5229 N N   . SER C 1 203 ? -12.372 -7.535  -22.137 1.00 13.44 ? 205 SER C N   1 
ATOM   5230 C CA  . SER C 1 203 ? -11.110 -8.199  -21.832 1.00 16.21 ? 205 SER C CA  1 
ATOM   5231 C C   . SER C 1 203 ? -10.392 -7.470  -20.707 1.00 18.58 ? 205 SER C C   1 
ATOM   5232 O O   . SER C 1 203 ? -10.298 -6.241  -20.726 1.00 17.28 ? 205 SER C O   1 
ATOM   5233 C CB  . SER C 1 203 ? -10.205 -8.272  -23.066 1.00 14.23 ? 205 SER C CB  1 
ATOM   5234 O OG  . SER C 1 203 ? -10.904 -8.811  -24.168 1.00 16.47 ? 205 SER C OG  1 
ATOM   5235 N N   . THR C 1 204 ? -9.887  -8.227  -19.733 1.00 13.71 ? 206 THR C N   1 
ATOM   5236 C CA  . THR C 1 204 ? -9.060  -7.683  -18.662 1.00 13.90 ? 206 THR C CA  1 
ATOM   5237 C C   . THR C 1 204 ? -7.716  -8.386  -18.665 1.00 16.31 ? 206 THR C C   1 
ATOM   5238 O O   . THR C 1 204 ? -7.662  -9.613  -18.545 1.00 17.19 ? 206 THR C O   1 
ATOM   5239 C CB  . THR C 1 204 ? -9.736  -7.827  -17.292 1.00 19.67 ? 206 THR C CB  1 
ATOM   5240 O OG1 . THR C 1 204 ? -11.064 -7.288  -17.350 1.00 17.80 ? 206 THR C OG1 1 
ATOM   5241 C CG2 . THR C 1 204 ? -8.924  -7.102  -16.214 1.00 18.64 ? 206 THR C CG2 1 
ATOM   5242 N N   . LEU C 1 205 ? -6.644  -7.607  -18.793 1.00 15.30 ? 207 LEU C N   1 
ATOM   5243 C CA  . LEU C 1 205 ? -5.280  -8.115  -18.769 1.00 15.49 ? 207 LEU C CA  1 
ATOM   5244 C C   . LEU C 1 205 ? -4.658  -7.877  -17.404 1.00 18.87 ? 207 LEU C C   1 
ATOM   5245 O O   . LEU C 1 205 ? -4.841  -6.817  -16.795 1.00 18.35 ? 207 LEU C O   1 
ATOM   5246 C CB  . LEU C 1 205 ? -4.403  -7.454  -19.836 1.00 16.59 ? 207 LEU C CB  1 
ATOM   5247 C CG  . LEU C 1 205 ? -4.936  -7.343  -21.264 1.00 18.96 ? 207 LEU C CG  1 
ATOM   5248 C CD1 . LEU C 1 205 ? -3.839  -6.942  -22.241 1.00 16.43 ? 207 LEU C CD1 1 
ATOM   5249 C CD2 . LEU C 1 205 ? -5.542  -8.637  -21.663 1.00 20.11 ? 207 LEU C CD2 1 
ATOM   5250 N N   . SER C 1 206 ? -3.914  -8.861  -16.924 1.00 16.35 ? 208 SER C N   1 
ATOM   5251 C CA  . SER C 1 206 ? -3.278  -8.717  -15.626 1.00 17.14 ? 208 SER C CA  1 
ATOM   5252 C C   . SER C 1 206 ? -1.997  -9.532  -15.634 1.00 21.08 ? 208 SER C C   1 
ATOM   5253 O O   . SER C 1 206 ? -1.631  -10.142 -16.643 1.00 16.54 ? 208 SER C O   1 
ATOM   5254 C CB  . SER C 1 206 ? -4.209  -9.161  -14.492 1.00 17.83 ? 208 SER C CB  1 
ATOM   5255 O OG  . SER C 1 206 ? -4.681  -10.480 -14.711 1.00 20.64 ? 208 SER C OG  1 
ATOM   5256 N N   . LYS C 1 207 ? -1.321  -9.539  -14.486 1.00 19.11 ? 209 LYS C N   1 
ATOM   5257 C CA  . LYS C 1 207 ? -0.078  -10.265 -14.300 1.00 21.21 ? 209 LYS C CA  1 
ATOM   5258 C C   . LYS C 1 207 ? -0.217  -11.192 -13.099 1.00 24.37 ? 209 LYS C C   1 
ATOM   5259 O O   . LYS C 1 207 ? -1.010  -10.947 -12.183 1.00 22.30 ? 209 LYS C O   1 
ATOM   5260 C CB  . LYS C 1 207 ? 1.111   -9.304  -14.100 1.00 20.89 ? 209 LYS C CB  1 
ATOM   5261 C CG  . LYS C 1 207 ? 1.401   -8.377  -15.280 1.00 19.91 ? 209 LYS C CG  1 
ATOM   5262 C CD  . LYS C 1 207 ? 2.076   -9.106  -16.441 1.00 16.37 ? 209 LYS C CD  1 
ATOM   5263 C CE  . LYS C 1 207 ? 2.477   -8.118  -17.534 1.00 20.77 ? 209 LYS C CE  1 
ATOM   5264 N NZ  . LYS C 1 207 ? 3.011   -8.783  -18.758 1.00 16.91 ? 209 LYS C NZ  1 
ATOM   5265 N N   . ASP C 1 208 ? 0.536   -12.284 -13.146 1.00 21.38 ? 210 ASP C N   1 
ATOM   5266 C CA  . ASP C 1 208 ? 0.597   -13.251 -12.064 1.00 22.80 ? 210 ASP C CA  1 
ATOM   5267 C C   . ASP C 1 208 ? 1.800   -12.869 -11.210 1.00 22.84 ? 210 ASP C C   1 
ATOM   5268 O O   . ASP C 1 208 ? 2.932   -12.888 -11.717 1.00 21.88 ? 210 ASP C O   1 
ATOM   5269 C CB  . ASP C 1 208 ? 0.740   -14.658 -12.643 1.00 21.52 ? 210 ASP C CB  1 
ATOM   5270 C CG  . ASP C 1 208 ? 0.925   -15.727 -11.592 1.00 27.08 ? 210 ASP C CG  1 
ATOM   5271 O OD1 . ASP C 1 208 ? 0.955   -15.408 -10.391 1.00 26.14 ? 210 ASP C OD1 1 
ATOM   5272 O OD2 . ASP C 1 208 ? 1.023   -16.907 -11.987 1.00 29.91 ? 210 ASP C OD2 1 
ATOM   5273 N N   . PRO C 1 209 ? 1.612   -12.479 -9.943  1.00 26.25 ? 211 PRO C N   1 
ATOM   5274 C CA  . PRO C 1 209 ? 2.746   -11.940 -9.167  1.00 27.38 ? 211 PRO C CA  1 
ATOM   5275 C C   . PRO C 1 209 ? 3.839   -12.956 -8.936  1.00 26.36 ? 211 PRO C C   1 
ATOM   5276 O O   . PRO C 1 209 ? 4.993   -12.571 -8.711  1.00 30.49 ? 211 PRO C O   1 
ATOM   5277 C CB  . PRO C 1 209 ? 2.119   -11.514 -7.830  1.00 24.23 ? 211 PRO C CB  1 
ATOM   5278 C CG  . PRO C 1 209 ? 0.693   -11.863 -7.884  1.00 27.75 ? 211 PRO C CG  1 
ATOM   5279 C CD  . PRO C 1 209 ? 0.358   -12.543 -9.175  1.00 25.66 ? 211 PRO C CD  1 
ATOM   5280 N N   . ASN C 1 210 ? 3.512   -14.239 -8.980  1.00 26.88 ? 212 ASN C N   1 
ATOM   5281 C CA  . ASN C 1 210 ? 4.459   -15.323 -8.775  1.00 25.83 ? 212 ASN C CA  1 
ATOM   5282 C C   . ASN C 1 210 ? 5.103   -15.812 -10.066 1.00 30.50 ? 212 ASN C C   1 
ATOM   5283 O O   . ASN C 1 210 ? 5.921   -16.738 -10.017 1.00 30.24 ? 212 ASN C O   1 
ATOM   5284 C CB  . ASN C 1 210 ? 3.748   -16.492 -8.103  1.00 29.11 ? 212 ASN C CB  1 
ATOM   5285 C CG  . ASN C 1 210 ? 3.209   -16.131 -6.738  1.00 32.82 ? 212 ASN C CG  1 
ATOM   5286 O OD1 . ASN C 1 210 ? 3.708   -15.213 -6.086  1.00 33.85 ? 212 ASN C OD1 1 
ATOM   5287 N ND2 . ASN C 1 210 ? 2.158   -16.819 -6.316  1.00 35.44 ? 212 ASN C ND2 1 
ATOM   5288 N N   . GLU C 1 211 ? 4.747   -15.248 -11.220 1.00 28.55 ? 213 GLU C N   1 
ATOM   5289 C CA  . GLU C 1 211 ? 5.237   -15.743 -12.499 1.00 22.49 ? 213 GLU C CA  1 
ATOM   5290 C C   . GLU C 1 211 ? 6.408   -14.877 -12.946 1.00 23.52 ? 213 GLU C C   1 
ATOM   5291 O O   . GLU C 1 211 ? 6.262   -13.665 -13.126 1.00 26.68 ? 213 GLU C O   1 
ATOM   5292 C CB  . GLU C 1 211 ? 4.127   -15.742 -13.550 1.00 22.21 ? 213 GLU C CB  1 
ATOM   5293 C CG  . GLU C 1 211 ? 4.573   -16.195 -14.927 1.00 22.87 ? 213 GLU C CG  1 
ATOM   5294 C CD  . GLU C 1 211 ? 5.053   -17.631 -14.921 1.00 21.04 ? 213 GLU C CD  1 
ATOM   5295 O OE1 . GLU C 1 211 ? 4.226   -18.535 -14.703 1.00 24.15 ? 213 GLU C OE1 1 
ATOM   5296 O OE2 . GLU C 1 211 ? 6.261   -17.851 -15.108 1.00 26.46 ? 213 GLU C OE2 1 
ATOM   5297 N N   . LYS C 1 212 ? 7.564   -15.503 -13.117 1.00 24.64 ? 214 LYS C N   1 
ATOM   5298 C CA  . LYS C 1 212 ? 8.782   -14.825 -13.532 1.00 27.43 ? 214 LYS C CA  1 
ATOM   5299 C C   . LYS C 1 212 ? 8.962   -14.798 -15.045 1.00 23.89 ? 214 LYS C C   1 
ATOM   5300 O O   . LYS C 1 212 ? 9.716   -13.963 -15.557 1.00 24.35 ? 214 LYS C O   1 
ATOM   5301 C CB  . LYS C 1 212 ? 10.008  -15.494 -12.879 1.00 30.79 ? 214 LYS C CB  1 
ATOM   5302 C CG  . LYS C 1 212 ? 10.368  -16.914 -13.366 1.00 34.40 ? 214 LYS C CG  1 
ATOM   5303 C CD  . LYS C 1 212 ? 9.173   -17.881 -13.387 1.00 39.75 ? 214 LYS C CD  1 
ATOM   5304 C CE  . LYS C 1 212 ? 9.546   -19.353 -13.415 1.00 40.49 ? 214 LYS C CE  1 
ATOM   5305 N NZ  . LYS C 1 212 ? 8.307   -20.131 -13.762 1.00 41.22 ? 214 LYS C NZ  1 
ATOM   5306 N N   . ARG C 1 213 ? 8.299   -15.686 -15.772 1.00 22.78 ? 215 ARG C N   1 
ATOM   5307 C CA  . ARG C 1 213 ? 8.397   -15.619 -17.219 1.00 22.47 ? 215 ARG C CA  1 
ATOM   5308 C C   . ARG C 1 213 ? 7.526   -14.490 -17.763 1.00 18.49 ? 215 ARG C C   1 
ATOM   5309 O O   . ARG C 1 213 ? 6.613   -14.003 -17.094 1.00 17.51 ? 215 ARG C O   1 
ATOM   5310 C CB  . ARG C 1 213 ? 8.007   -16.955 -17.845 1.00 20.96 ? 215 ARG C CB  1 
ATOM   5311 C CG  . ARG C 1 213 ? 9.030   -18.026 -17.578 1.00 27.57 ? 215 ARG C CG  1 
ATOM   5312 C CD  . ARG C 1 213 ? 8.477   -19.410 -17.780 1.00 32.15 ? 215 ARG C CD  1 
ATOM   5313 N NE  . ARG C 1 213 ? 7.533   -19.775 -16.731 1.00 37.54 ? 215 ARG C NE  1 
ATOM   5314 C CZ  . ARG C 1 213 ? 6.773   -20.864 -16.751 1.00 40.54 ? 215 ARG C CZ  1 
ATOM   5315 N NH1 . ARG C 1 213 ? 6.820   -21.722 -17.765 1.00 39.77 ? 215 ARG C NH1 1 
ATOM   5316 N NH2 . ARG C 1 213 ? 5.961   -21.109 -15.722 1.00 42.17 ? 215 ARG C NH2 1 
ATOM   5317 N N   . ASP C 1 214 ? 7.867   -14.048 -18.974 1.00 16.13 ? 216 ASP C N   1 
ATOM   5318 C CA  . ASP C 1 214 ? 7.058   -13.068 -19.699 1.00 17.65 ? 216 ASP C CA  1 
ATOM   5319 C C   . ASP C 1 214 ? 5.701   -13.680 -19.994 1.00 15.22 ? 216 ASP C C   1 
ATOM   5320 O O   . ASP C 1 214 ? 5.625   -14.786 -20.537 1.00 14.30 ? 216 ASP C O   1 
ATOM   5321 C CB  . ASP C 1 214 ? 7.756   -12.676 -20.995 1.00 16.77 ? 216 ASP C CB  1 
ATOM   5322 C CG  . ASP C 1 214 ? 7.264   -11.360 -21.568 1.00 19.26 ? 216 ASP C CG  1 
ATOM   5323 O OD1 . ASP C 1 214 ? 6.325   -10.743 -21.010 1.00 15.53 ? 216 ASP C OD1 1 
ATOM   5324 O OD2 . ASP C 1 214 ? 7.824   -10.955 -22.607 1.00 16.69 ? 216 ASP C OD2 1 
ATOM   5325 N N   . HIS C 1 215 ? 4.628   -12.974 -19.642 1.00 15.96 ? 217 HIS C N   1 
ATOM   5326 C CA  . HIS C 1 215 ? 3.336   -13.642 -19.586 1.00 14.08 ? 217 HIS C CA  1 
ATOM   5327 C C   . HIS C 1 215 ? 2.207   -12.619 -19.606 1.00 15.30 ? 217 HIS C C   1 
ATOM   5328 O O   . HIS C 1 215 ? 2.417   -11.418 -19.423 1.00 14.28 ? 217 HIS C O   1 
ATOM   5329 C CB  . HIS C 1 215 ? 3.241   -14.530 -18.338 1.00 13.84 ? 217 HIS C CB  1 
ATOM   5330 C CG  . HIS C 1 215 ? 3.039   -13.762 -17.070 1.00 16.39 ? 217 HIS C CG  1 
ATOM   5331 N ND1 . HIS C 1 215 ? 4.076   -13.146 -16.397 1.00 18.51 ? 217 HIS C ND1 1 
ATOM   5332 C CD2 . HIS C 1 215 ? 1.920   -13.496 -16.359 1.00 18.54 ? 217 HIS C CD2 1 
ATOM   5333 C CE1 . HIS C 1 215 ? 3.602   -12.533 -15.326 1.00 18.54 ? 217 HIS C CE1 1 
ATOM   5334 N NE2 . HIS C 1 215 ? 2.297   -12.732 -15.279 1.00 18.42 ? 217 HIS C NE2 1 
ATOM   5335 N N   . MET C 1 216 ? 0.998   -13.138 -19.839 1.00 12.49 ? 218 MET C N   1 
ATOM   5336 C CA  . MET C 1 216 ? -0.257  -12.391 -19.859 1.00 14.21 ? 218 MET C CA  1 
ATOM   5337 C C   . MET C 1 216 ? -1.328  -13.244 -19.216 1.00 13.88 ? 218 MET C C   1 
ATOM   5338 O O   . MET C 1 216 ? -1.558  -14.365 -19.670 1.00 14.85 ? 218 MET C O   1 
ATOM   5339 C CB  . MET C 1 216 ? -0.699  -12.066 -21.287 1.00 14.75 ? 218 MET C CB  1 
ATOM   5340 C CG  . MET C 1 216 ? -2.065  -11.374 -21.362 1.00 12.71 ? 218 MET C CG  1 
ATOM   5341 S SD  . MET C 1 216 ? -2.390  -10.576 -22.952 1.00 13.15 ? 218 MET C SD  1 
ATOM   5342 C CE  . MET C 1 216 ? -2.589  -12.047 -24.001 1.00 13.06 ? 218 MET C CE  1 
ATOM   5343 N N   . VAL C 1 217 ? -2.004  -12.712 -18.202 1.00 12.64 ? 219 VAL C N   1 
ATOM   5344 C CA  . VAL C 1 217 ? -3.232  -13.301 -17.683 1.00 15.41 ? 219 VAL C CA  1 
ATOM   5345 C C   . VAL C 1 217 ? -4.387  -12.548 -18.313 1.00 14.56 ? 219 VAL C C   1 
ATOM   5346 O O   . VAL C 1 217 ? -4.360  -11.312 -18.387 1.00 12.86 ? 219 VAL C O   1 
ATOM   5347 C CB  . VAL C 1 217 ? -3.294  -13.230 -16.149 1.00 18.35 ? 219 VAL C CB  1 
ATOM   5348 C CG1 . VAL C 1 217 ? -4.640  -13.779 -15.638 1.00 14.46 ? 219 VAL C CG1 1 
ATOM   5349 C CG2 . VAL C 1 217 ? -2.135  -14.019 -15.559 1.00 15.58 ? 219 VAL C CG2 1 
ATOM   5350 N N   . LEU C 1 218 ? -5.378  -13.287 -18.798 1.00 13.58 ? 220 LEU C N   1 
ATOM   5351 C CA  . LEU C 1 218 ? -6.472  -12.716 -19.566 1.00 15.06 ? 220 LEU C CA  1 
ATOM   5352 C C   . LEU C 1 218 ? -7.797  -13.288 -19.087 1.00 16.64 ? 220 LEU C C   1 
ATOM   5353 O O   . LEU C 1 218 ? -7.961  -14.513 -18.980 1.00 16.69 ? 220 LEU C O   1 
ATOM   5354 C CB  . LEU C 1 218 ? -6.282  -12.980 -21.076 1.00 16.34 ? 220 LEU C CB  1 
ATOM   5355 C CG  . LEU C 1 218 ? -7.463  -12.679 -22.010 1.00 20.38 ? 220 LEU C CG  1 
ATOM   5356 C CD1 . LEU C 1 218 ? -7.658  -11.195 -22.185 1.00 22.66 ? 220 LEU C CD1 1 
ATOM   5357 C CD2 . LEU C 1 218 ? -7.221  -13.281 -23.386 1.00 24.02 ? 220 LEU C CD2 1 
ATOM   5358 N N   . LEU C 1 219 ? -8.736  -12.395 -18.804 1.00 14.28 ? 221 LEU C N   1 
ATOM   5359 C CA  . LEU C 1 219 ? -10.096 -12.750 -18.433 1.00 14.55 ? 221 LEU C CA  1 
ATOM   5360 C C   . LEU C 1 219 ? -11.038 -12.074 -19.415 1.00 15.15 ? 221 LEU C C   1 
ATOM   5361 O O   . LEU C 1 219 ? -10.911 -10.876 -19.678 1.00 15.52 ? 221 LEU C O   1 
ATOM   5362 C CB  . LEU C 1 219 ? -10.405 -12.305 -17.008 1.00 13.65 ? 221 LEU C CB  1 
ATOM   5363 C CG  . LEU C 1 219 ? -11.868 -12.260 -16.597 1.00 17.32 ? 221 LEU C CG  1 
ATOM   5364 C CD1 . LEU C 1 219 ? -12.375 -13.668 -16.452 1.00 19.08 ? 221 LEU C CD1 1 
ATOM   5365 C CD2 . LEU C 1 219 ? -12.003 -11.546 -15.275 1.00 18.33 ? 221 LEU C CD2 1 
ATOM   5366 N N   . GLU C 1 220 ? -11.968 -12.831 -19.966 1.00 15.71 ? 222 GLU C N   1 
ATOM   5367 C CA  . GLU C 1 220 ? -12.775 -12.291 -21.039 1.00 14.81 ? 222 GLU C CA  1 
ATOM   5368 C C   . GLU C 1 220 ? -14.210 -12.735 -20.835 1.00 18.05 ? 222 GLU C C   1 
ATOM   5369 O O   . GLU C 1 220 ? -14.461 -13.859 -20.388 1.00 16.27 ? 222 GLU C O   1 
ATOM   5370 C CB  . GLU C 1 220 ? -12.204 -12.757 -22.384 1.00 18.55 ? 222 GLU C CB  1 
ATOM   5371 C CG  . GLU C 1 220 ? -12.033 -11.677 -23.404 1.00 20.64 ? 222 GLU C CG  1 
ATOM   5372 C CD  . GLU C 1 220 ? -11.132 -12.108 -24.535 1.00 25.62 ? 222 GLU C CD  1 
ATOM   5373 O OE1 . GLU C 1 220 ? -11.326 -13.240 -25.012 1.00 23.55 ? 222 GLU C OE1 1 
ATOM   5374 O OE2 . GLU C 1 220 ? -10.309 -11.282 -25.015 1.00 22.87 ? 222 GLU C OE2 1 
ATOM   5375 N N   . PHE C 1 221 ? -15.141 -11.821 -21.106 1.00 14.31 ? 223 PHE C N   1 
ATOM   5376 C CA  . PHE C 1 221 ? -16.561 -12.129 -21.167 1.00 14.16 ? 223 PHE C CA  1 
ATOM   5377 C C   . PHE C 1 221 ? -17.066 -11.773 -22.552 1.00 15.16 ? 223 PHE C C   1 
ATOM   5378 O O   . PHE C 1 221 ? -16.731 -10.712 -23.085 1.00 16.88 ? 223 PHE C O   1 
ATOM   5379 C CB  . PHE C 1 221 ? -17.344 -11.352 -20.105 1.00 13.88 ? 223 PHE C CB  1 
ATOM   5380 C CG  . PHE C 1 221 ? -16.882 -11.618 -18.718 1.00 15.13 ? 223 PHE C CG  1 
ATOM   5381 C CD1 . PHE C 1 221 ? -17.427 -12.654 -17.987 1.00 16.58 ? 223 PHE C CD1 1 
ATOM   5382 C CD2 . PHE C 1 221 ? -15.867 -10.859 -18.155 1.00 16.24 ? 223 PHE C CD2 1 
ATOM   5383 C CE1 . PHE C 1 221 ? -16.989 -12.913 -16.705 1.00 19.65 ? 223 PHE C CE1 1 
ATOM   5384 C CE2 . PHE C 1 221 ? -15.425 -11.115 -16.864 1.00 14.94 ? 223 PHE C CE2 1 
ATOM   5385 C CZ  . PHE C 1 221 ? -15.993 -12.138 -16.143 1.00 16.95 ? 223 PHE C CZ  1 
ATOM   5386 N N   . VAL C 1 222 ? -17.882 -12.636 -23.141 1.00 15.13 ? 224 VAL C N   1 
ATOM   5387 C CA  . VAL C 1 222 ? -18.253 -12.405 -24.533 1.00 16.28 ? 224 VAL C CA  1 
ATOM   5388 C C   . VAL C 1 222 ? -19.669 -12.906 -24.773 1.00 19.40 ? 224 VAL C C   1 
ATOM   5389 O O   . VAL C 1 222 ? -20.054 -13.988 -24.318 1.00 18.63 ? 224 VAL C O   1 
ATOM   5390 C CB  . VAL C 1 222 ? -17.230 -13.042 -25.500 1.00 20.08 ? 224 VAL C CB  1 
ATOM   5391 C CG1 . VAL C 1 222 ? -16.857 -14.429 -25.045 1.00 20.11 ? 224 VAL C CG1 1 
ATOM   5392 C CG2 . VAL C 1 222 ? -17.744 -13.028 -26.954 1.00 21.05 ? 224 VAL C CG2 1 
ATOM   5393 N N   . THR C 1 223 ? -20.449 -12.100 -25.478 1.00 18.14 ? 225 THR C N   1 
ATOM   5394 C CA  . THR C 1 223 ? -21.795 -12.484 -25.847 1.00 19.80 ? 225 THR C CA  1 
ATOM   5395 C C   . THR C 1 223 ? -22.059 -12.122 -27.300 1.00 16.84 ? 225 THR C C   1 
ATOM   5396 O O   . THR C 1 223 ? -21.544 -11.123 -27.812 1.00 16.83 ? 225 THR C O   1 
ATOM   5397 C CB  . THR C 1 223 ? -22.812 -11.796 -24.965 1.00 22.61 ? 225 THR C CB  1 
ATOM   5398 O OG1 . THR C 1 223 ? -24.117 -12.256 -25.325 1.00 27.06 ? 225 THR C OG1 1 
ATOM   5399 C CG2 . THR C 1 223 ? -22.759 -10.260 -25.190 1.00 17.74 ? 225 THR C CG2 1 
ATOM   5400 N N   . ALA C 1 224 ? -22.844 -12.962 -27.969 1.00 19.89 ? 226 ALA C N   1 
ATOM   5401 C CA  . ALA C 1 224 ? -23.401 -12.604 -29.261 1.00 19.86 ? 226 ALA C CA  1 
ATOM   5402 C C   . ALA C 1 224 ? -24.687 -11.817 -29.054 1.00 24.20 ? 226 ALA C C   1 
ATOM   5403 O O   . ALA C 1 224 ? -25.301 -11.861 -27.981 1.00 24.43 ? 226 ALA C O   1 
ATOM   5404 C CB  . ALA C 1 224 ? -23.685 -13.843 -30.102 1.00 21.26 ? 226 ALA C CB  1 
ATOM   5405 N N   . ALA C 1 225 ? -25.087 -11.081 -30.092 1.00 21.87 ? 227 ALA C N   1 
ATOM   5406 C CA  . ALA C 1 225 ? -26.270 -10.235 -29.999 1.00 26.87 ? 227 ALA C CA  1 
ATOM   5407 C C   . ALA C 1 225 ? -26.804 -9.944  -31.395 1.00 30.92 ? 227 ALA C C   1 
ATOM   5408 O O   . ALA C 1 225 ? -26.029 -9.742  -32.332 1.00 26.47 ? 227 ALA C O   1 
ATOM   5409 C CB  . ALA C 1 225 ? -25.964 -8.922  -29.264 1.00 28.58 ? 227 ALA C CB  1 
ATOM   5410 N N   . GLY C 1 226 ? -28.133 -9.922  -31.518 1.00 36.78 ? 228 GLY C N   1 
ATOM   5411 C CA  . GLY C 1 226 ? -28.784 -9.793  -32.805 1.00 38.22 ? 228 GLY C CA  1 
ATOM   5412 C C   . GLY C 1 226 ? -28.711 -8.389  -33.376 1.00 43.59 ? 228 GLY C C   1 
ATOM   5413 O O   . GLY C 1 226 ? -28.146 -7.465  -32.789 1.00 44.09 ? 228 GLY C O   1 
ATOM   5414 N N   . ILE C 1 227 ? -29.305 -8.245  -34.561 1.00 46.64 ? 229 ILE C N   1 
ATOM   5415 C CA  . ILE C 1 227 ? -29.349 -6.979  -35.294 1.00 48.22 ? 229 ILE C CA  1 
ATOM   5416 C C   . ILE C 1 227 ? -27.943 -6.539  -35.684 1.00 46.46 ? 229 ILE C C   1 
ATOM   5417 O O   . ILE C 1 227 ? -27.451 -6.887  -36.761 1.00 46.19 ? 229 ILE C O   1 
ATOM   5418 C CB  . ILE C 1 227 ? -30.062 -5.878  -34.483 1.00 50.26 ? 229 ILE C CB  1 
ATOM   5419 C CG1 . ILE C 1 227 ? -31.573 -6.106  -34.492 1.00 42.98 ? 229 ILE C CG1 1 
ATOM   5420 C CG2 . ILE C 1 227 ? -29.705 -4.494  -35.023 1.00 52.41 ? 229 ILE C CG2 1 
ATOM   5421 C CD1 . ILE C 1 227 ? -32.255 -5.583  -33.255 1.00 49.64 ? 229 ILE C CD1 1 
ATOM   5422 N N   . LYS D 1 3   ? -28.670 20.832  -52.965 1.00 37.49 ? 3   LYS D N   1 
ATOM   5423 C CA  . LYS D 1 3   ? -28.864 19.404  -53.188 1.00 29.54 ? 3   LYS D CA  1 
ATOM   5424 C C   . LYS D 1 3   ? -27.844 18.857  -54.181 1.00 30.44 ? 3   LYS D C   1 
ATOM   5425 O O   . LYS D 1 3   ? -27.993 19.021  -55.392 1.00 27.74 ? 3   LYS D O   1 
ATOM   5426 C CB  . LYS D 1 3   ? -30.284 19.127  -53.685 1.00 32.35 ? 3   LYS D CB  1 
ATOM   5427 C CG  . LYS D 1 3   ? -31.327 19.067  -52.582 1.00 34.33 ? 3   LYS D CG  1 
ATOM   5428 C CD  . LYS D 1 3   ? -32.469 18.134  -52.952 1.00 36.73 ? 3   LYS D CD  1 
ATOM   5429 C CE  . LYS D 1 3   ? -33.487 18.832  -53.839 1.00 40.23 ? 3   LYS D CE  1 
ATOM   5430 N NZ  . LYS D 1 3   ? -34.612 17.930  -54.210 1.00 40.87 ? 3   LYS D NZ  1 
ATOM   5431 N N   . GLY D 1 4   ? -26.808 18.207  -53.661 1.00 25.43 ? 4   GLY D N   1 
ATOM   5432 C CA  . GLY D 1 4   ? -25.771 17.640  -54.494 1.00 24.46 ? 4   GLY D CA  1 
ATOM   5433 C C   . GLY D 1 4   ? -26.337 16.886  -55.679 1.00 22.74 ? 4   GLY D C   1 
ATOM   5434 O O   . GLY D 1 4   ? -25.693 16.801  -56.725 1.00 22.35 ? 4   GLY D O   1 
ATOM   5435 N N   . GLU D 1 5   ? -27.544 16.352  -55.522 1.00 22.45 ? 5   GLU D N   1 
ATOM   5436 C CA  . GLU D 1 5   ? -28.206 15.626  -56.599 1.00 25.39 ? 5   GLU D CA  1 
ATOM   5437 C C   . GLU D 1 5   ? -28.363 16.504  -57.837 1.00 26.30 ? 5   GLU D C   1 
ATOM   5438 O O   . GLU D 1 5   ? -28.097 16.066  -58.956 1.00 22.71 ? 5   GLU D O   1 
ATOM   5439 C CB  . GLU D 1 5   ? -29.574 15.117  -56.139 1.00 29.14 ? 5   GLU D CB  1 
ATOM   5440 C CG  . GLU D 1 5   ? -29.508 14.078  -55.031 1.00 30.26 ? 5   GLU D CG  1 
ATOM   5441 C CD  . GLU D 1 5   ? -28.693 12.861  -55.420 1.00 46.56 ? 5   GLU D CD  1 
ATOM   5442 O OE1 . GLU D 1 5   ? -28.806 12.415  -56.581 1.00 41.72 ? 5   GLU D OE1 1 
ATOM   5443 O OE2 . GLU D 1 5   ? -27.940 12.349  -54.565 1.00 45.10 ? 5   GLU D OE2 1 
ATOM   5444 N N   . GLU D 1 6   ? -28.794 17.744  -57.629 1.00 26.24 ? 6   GLU D N   1 
ATOM   5445 C CA  . GLU D 1 6   ? -28.981 18.682  -58.726 1.00 27.73 ? 6   GLU D CA  1 
ATOM   5446 C C   . GLU D 1 6   ? -27.710 18.897  -59.541 1.00 25.52 ? 6   GLU D C   1 
ATOM   5447 O O   . GLU D 1 6   ? -27.797 19.241  -60.725 1.00 27.69 ? 6   GLU D O   1 
ATOM   5448 C CB  . GLU D 1 6   ? -29.491 20.015  -58.176 1.00 30.34 ? 6   GLU D CB  1 
ATOM   5449 C CG  . GLU D 1 6   ? -30.783 19.935  -57.338 1.00 37.01 ? 6   GLU D CG  1 
ATOM   5450 C CD  . GLU D 1 6   ? -32.018 19.422  -58.086 1.00 45.01 ? 6   GLU D CD  1 
ATOM   5451 O OE1 . GLU D 1 6   ? -31.910 18.673  -59.086 1.00 48.02 ? 6   GLU D OE1 1 
ATOM   5452 O OE2 . GLU D 1 6   ? -33.130 19.789  -57.646 1.00 49.55 ? 6   GLU D OE2 1 
ATOM   5453 N N   . LEU D 1 7   ? -26.534 18.683  -58.951 1.00 22.33 ? 7   LEU D N   1 
ATOM   5454 C CA  . LEU D 1 7   ? -25.289 18.824  -59.696 1.00 21.41 ? 7   LEU D CA  1 
ATOM   5455 C C   . LEU D 1 7   ? -25.114 17.747  -60.765 1.00 22.60 ? 7   LEU D C   1 
ATOM   5456 O O   . LEU D 1 7   ? -24.213 17.879  -61.603 1.00 20.63 ? 7   LEU D O   1 
ATOM   5457 C CB  . LEU D 1 7   ? -24.105 18.798  -58.723 1.00 22.06 ? 7   LEU D CB  1 
ATOM   5458 C CG  . LEU D 1 7   ? -23.944 20.019  -57.805 1.00 20.74 ? 7   LEU D CG  1 
ATOM   5459 C CD1 . LEU D 1 7   ? -22.741 19.848  -56.871 1.00 22.66 ? 7   LEU D CD1 1 
ATOM   5460 C CD2 . LEU D 1 7   ? -23.824 21.326  -58.589 1.00 20.01 ? 7   LEU D CD2 1 
ATOM   5461 N N   . PHE D 1 8   ? -25.959 16.707  -60.778 1.00 21.66 ? 8   PHE D N   1 
ATOM   5462 C CA  . PHE D 1 8   ? -25.782 15.560  -61.667 1.00 20.27 ? 8   PHE D CA  1 
ATOM   5463 C C   . PHE D 1 8   ? -26.882 15.415  -62.723 1.00 23.17 ? 8   PHE D C   1 
ATOM   5464 O O   . PHE D 1 8   ? -26.973 14.362  -63.362 1.00 22.51 ? 8   PHE D O   1 
ATOM   5465 C CB  . PHE D 1 8   ? -25.702 14.258  -60.862 1.00 18.75 ? 8   PHE D CB  1 
ATOM   5466 C CG  . PHE D 1 8   ? -24.464 14.135  -60.025 1.00 16.97 ? 8   PHE D CG  1 
ATOM   5467 C CD1 . PHE D 1 8   ? -24.392 14.714  -58.772 1.00 17.51 ? 8   PHE D CD1 1 
ATOM   5468 C CD2 . PHE D 1 8   ? -23.346 13.505  -60.528 1.00 14.48 ? 8   PHE D CD2 1 
ATOM   5469 C CE1 . PHE D 1 8   ? -23.243 14.618  -58.013 1.00 19.26 ? 8   PHE D CE1 1 
ATOM   5470 C CE2 . PHE D 1 8   ? -22.190 13.406  -59.774 1.00 16.90 ? 8   PHE D CE2 1 
ATOM   5471 C CZ  . PHE D 1 8   ? -22.143 13.960  -58.515 1.00 17.39 ? 8   PHE D CZ  1 
ATOM   5472 N N   . THR D 1 9   ? -27.725 16.433  -62.927 1.00 25.98 ? 9   THR D N   1 
ATOM   5473 C CA  . THR D 1 9   ? -28.837 16.280  -63.870 1.00 21.76 ? 9   THR D CA  1 
ATOM   5474 C C   . THR D 1 9   ? -28.385 16.251  -65.324 1.00 28.49 ? 9   THR D C   1 
ATOM   5475 O O   . THR D 1 9   ? -29.131 15.754  -66.178 1.00 28.31 ? 9   THR D O   1 
ATOM   5476 C CB  . THR D 1 9   ? -29.861 17.401  -63.688 1.00 29.72 ? 9   THR D CB  1 
ATOM   5477 O OG1 . THR D 1 9   ? -29.194 18.664  -63.740 1.00 27.04 ? 9   THR D OG1 1 
ATOM   5478 C CG2 . THR D 1 9   ? -30.565 17.263  -62.343 1.00 30.98 ? 9   THR D CG2 1 
ATOM   5479 N N   . GLY D 1 10  ? -27.202 16.780  -65.629 1.00 22.27 ? 10  GLY D N   1 
ATOM   5480 C CA  . GLY D 1 10  ? -26.702 16.772  -66.990 1.00 24.56 ? 10  GLY D CA  1 
ATOM   5481 C C   . GLY D 1 10  ? -25.354 16.085  -67.121 1.00 23.65 ? 10  GLY D C   1 
ATOM   5482 O O   . GLY D 1 10  ? -24.957 15.323  -66.237 1.00 21.75 ? 10  GLY D O   1 
ATOM   5483 N N   . VAL D 1 11  ? -24.637 16.351  -68.209 1.00 18.70 ? 11  VAL D N   1 
ATOM   5484 C CA  . VAL D 1 11  ? -23.329 15.747  -68.428 1.00 20.11 ? 11  VAL D CA  1 
ATOM   5485 C C   . VAL D 1 11  ? -22.309 16.487  -67.578 1.00 19.06 ? 11  VAL D C   1 
ATOM   5486 O O   . VAL D 1 11  ? -22.293 17.723  -67.560 1.00 21.25 ? 11  VAL D O   1 
ATOM   5487 C CB  . VAL D 1 11  ? -22.945 15.801  -69.913 1.00 21.42 ? 11  VAL D CB  1 
ATOM   5488 C CG1 . VAL D 1 11  ? -21.512 15.306  -70.102 1.00 20.47 ? 11  VAL D CG1 1 
ATOM   5489 C CG2 . VAL D 1 11  ? -23.941 15.003  -70.751 1.00 20.90 ? 11  VAL D CG2 1 
ATOM   5490 N N   . VAL D 1 12  ? -21.452 15.744  -66.884 1.00 16.73 ? 12  VAL D N   1 
ATOM   5491 C CA  . VAL D 1 12  ? -20.500 16.313  -65.937 1.00 16.57 ? 12  VAL D CA  1 
ATOM   5492 C C   . VAL D 1 12  ? -19.092 15.883  -66.337 1.00 16.99 ? 12  VAL D C   1 
ATOM   5493 O O   . VAL D 1 12  ? -18.821 14.682  -66.454 1.00 14.55 ? 12  VAL D O   1 
ATOM   5494 C CB  . VAL D 1 12  ? -20.793 15.884  -64.490 1.00 13.84 ? 12  VAL D CB  1 
ATOM   5495 C CG1 . VAL D 1 12  ? -19.699 16.433  -63.538 1.00 13.86 ? 12  VAL D CG1 1 
ATOM   5496 C CG2 . VAL D 1 12  ? -22.190 16.327  -64.071 1.00 16.75 ? 12  VAL D CG2 1 
ATOM   5497 N N   . PRO D 1 13  ? -18.161 16.817  -66.548 1.00 14.40 ? 13  PRO D N   1 
ATOM   5498 C CA  . PRO D 1 13  ? -16.782 16.418  -66.857 1.00 13.53 ? 13  PRO D CA  1 
ATOM   5499 C C   . PRO D 1 13  ? -16.164 15.721  -65.654 1.00 12.95 ? 13  PRO D C   1 
ATOM   5500 O O   . PRO D 1 13  ? -16.420 16.089  -64.504 1.00 12.54 ? 13  PRO D O   1 
ATOM   5501 C CB  . PRO D 1 13  ? -16.060 17.741  -67.150 1.00 16.98 ? 13  PRO D CB  1 
ATOM   5502 C CG  . PRO D 1 13  ? -17.083 18.844  -67.015 1.00 19.70 ? 13  PRO D CG  1 
ATOM   5503 C CD  . PRO D 1 13  ? -18.418 18.264  -66.681 1.00 17.49 ? 13  PRO D CD  1 
ATOM   5504 N N   . ILE D 1 14  ? -15.349 14.712  -65.929 1.00 12.89 ? 14  ILE D N   1 
ATOM   5505 C CA  . ILE D 1 14  ? -14.694 13.933  -64.884 1.00 13.03 ? 14  ILE D CA  1 
ATOM   5506 C C   . ILE D 1 14  ? -13.192 14.044  -65.050 1.00 10.78 ? 14  ILE D C   1 
ATOM   5507 O O   . ILE D 1 14  ? -12.671 13.920  -66.163 1.00 13.14 ? 14  ILE D O   1 
ATOM   5508 C CB  . ILE D 1 14  ? -15.097 12.446  -64.924 1.00 12.40 ? 14  ILE D CB  1 
ATOM   5509 C CG1 . ILE D 1 14  ? -16.588 12.286  -64.705 1.00 14.31 ? 14  ILE D CG1 1 
ATOM   5510 C CG2 . ILE D 1 14  ? -14.353 11.673  -63.851 1.00 11.11 ? 14  ILE D CG2 1 
ATOM   5511 C CD1 . ILE D 1 14  ? -17.027 10.838  -64.842 1.00 11.46 ? 14  ILE D CD1 1 
ATOM   5512 N N   . LEU D 1 15  ? -12.498 14.231  -63.934 1.00 11.71 ? 15  LEU D N   1 
ATOM   5513 C CA  . LEU D 1 15  ? -11.050 14.127  -63.874 1.00 12.05 ? 15  LEU D CA  1 
ATOM   5514 C C   . LEU D 1 15  ? -10.700 13.093  -62.817 1.00 10.09 ? 15  LEU D C   1 
ATOM   5515 O O   . LEU D 1 15  ? -11.287 13.092  -61.736 1.00 11.00 ? 15  LEU D O   1 
ATOM   5516 C CB  . LEU D 1 15  ? -10.417 15.470  -63.504 1.00 13.67 ? 15  LEU D CB  1 
ATOM   5517 C CG  . LEU D 1 15  ? -8.924  15.457  -63.167 1.00 15.01 ? 15  LEU D CG  1 
ATOM   5518 C CD1 . LEU D 1 15  ? -8.092  15.222  -64.417 1.00 14.36 ? 15  LEU D CD1 1 
ATOM   5519 C CD2 . LEU D 1 15  ? -8.524  16.786  -62.476 1.00 15.65 ? 15  LEU D CD2 1 
ATOM   5520 N N   . VAL D 1 16  ? -9.743  12.224  -63.125 1.00 11.13 ? 16  VAL D N   1 
ATOM   5521 C CA  . VAL D 1 16  ? -9.232  11.246  -62.174 1.00 9.73  ? 16  VAL D CA  1 
ATOM   5522 C C   . VAL D 1 16  ? -7.722  11.424  -62.093 1.00 12.25 ? 16  VAL D C   1 
ATOM   5523 O O   . VAL D 1 16  ? -7.050  11.535  -63.124 1.00 13.02 ? 16  VAL D O   1 
ATOM   5524 C CB  . VAL D 1 16  ? -9.583  9.798   -62.588 1.00 9.81  ? 16  VAL D CB  1 
ATOM   5525 C CG1 . VAL D 1 16  ? -9.035  8.804   -61.565 1.00 11.86 ? 16  VAL D CG1 1 
ATOM   5526 C CG2 . VAL D 1 16  ? -11.098 9.636   -62.737 1.00 11.12 ? 16  VAL D CG2 1 
ATOM   5527 N N   . GLU D 1 17  ? -7.180  11.452  -60.876 1.00 11.81 ? 17  GLU D N   1 
ATOM   5528 C CA  . GLU D 1 17  ? -5.733  11.565  -60.706 1.00 11.10 ? 17  GLU D CA  1 
ATOM   5529 C C   . GLU D 1 17  ? -5.316  10.558  -59.651 1.00 11.09 ? 17  GLU D C   1 
ATOM   5530 O O   . GLU D 1 17  ? -5.861  10.568  -58.548 1.00 12.47 ? 17  GLU D O   1 
ATOM   5531 C CB  . GLU D 1 17  ? -5.308  12.990  -60.293 1.00 14.17 ? 17  GLU D CB  1 
ATOM   5532 C CG  . GLU D 1 17  ? -5.528  14.094  -61.334 1.00 16.56 ? 17  GLU D CG  1 
ATOM   5533 C CD  . GLU D 1 17  ? -4.645  13.964  -62.577 1.00 16.64 ? 17  GLU D CD  1 
ATOM   5534 O OE1 . GLU D 1 17  ? -3.708  13.133  -62.573 1.00 16.24 ? 17  GLU D OE1 1 
ATOM   5535 O OE2 . GLU D 1 17  ? -4.898  14.699  -63.567 1.00 17.91 ? 17  GLU D OE2 1 
ATOM   5536 N N   . LEU D 1 18  ? -4.355  9.703   -59.978 1.00 10.72 ? 18  LEU D N   1 
ATOM   5537 C CA  . LEU D 1 18  ? -3.906  8.669   -59.062 1.00 13.13 ? 18  LEU D CA  1 
ATOM   5538 C C   . LEU D 1 18  ? -2.400  8.763   -58.910 1.00 12.98 ? 18  LEU D C   1 
ATOM   5539 O O   . LEU D 1 18  ? -1.675  8.844   -59.908 1.00 12.99 ? 18  LEU D O   1 
ATOM   5540 C CB  . LEU D 1 18  ? -4.292  7.275   -59.586 1.00 11.80 ? 18  LEU D CB  1 
ATOM   5541 C CG  . LEU D 1 18  ? -3.895  6.079   -58.721 1.00 14.90 ? 18  LEU D CG  1 
ATOM   5542 C CD1 . LEU D 1 18  ? -4.991  5.022   -58.752 1.00 15.60 ? 18  LEU D CD1 1 
ATOM   5543 C CD2 . LEU D 1 18  ? -2.592  5.516   -59.212 1.00 15.06 ? 18  LEU D CD2 1 
ATOM   5544 N N   . ASP D 1 19  ? -1.938  8.746   -57.668 1.00 13.20 ? 19  ASP D N   1 
ATOM   5545 C CA  . ASP D 1 19  ? -0.528  8.602   -57.342 1.00 14.30 ? 19  ASP D CA  1 
ATOM   5546 C C   . ASP D 1 19  ? -0.370  7.230   -56.710 1.00 13.22 ? 19  ASP D C   1 
ATOM   5547 O O   . ASP D 1 19  ? -1.054  6.927   -55.731 1.00 12.72 ? 19  ASP D O   1 
ATOM   5548 C CB  . ASP D 1 19  ? -0.079  9.703   -56.381 1.00 20.00 ? 19  ASP D CB  1 
ATOM   5549 C CG  . ASP D 1 19  ? 1.357   9.546   -55.958 1.00 23.00 ? 19  ASP D CG  1 
ATOM   5550 O OD1 . ASP D 1 19  ? 2.197   9.234   -56.830 1.00 30.03 ? 19  ASP D OD1 1 
ATOM   5551 O OD2 . ASP D 1 19  ? 1.636   9.741   -54.764 1.00 31.13 ? 19  ASP D OD2 1 
ATOM   5552 N N   . GLY D 1 20  ? 0.501   6.401   -57.278 1.00 14.44 ? 20  GLY D N   1 
ATOM   5553 C CA  . GLY D 1 20  ? 0.607   5.017   -56.866 1.00 12.44 ? 20  GLY D CA  1 
ATOM   5554 C C   . GLY D 1 20  ? 2.025   4.598   -56.535 1.00 13.49 ? 20  GLY D C   1 
ATOM   5555 O O   . GLY D 1 20  ? 2.998   5.144   -57.050 1.00 15.27 ? 20  GLY D O   1 
ATOM   5556 N N   . ASP D 1 21  ? 2.121   3.605   -55.656 1.00 14.26 ? 21  ASP D N   1 
ATOM   5557 C CA  . ASP D 1 21  ? 3.388   2.983   -55.281 1.00 15.18 ? 21  ASP D CA  1 
ATOM   5558 C C   . ASP D 1 21  ? 3.070   1.534   -54.948 1.00 12.76 ? 21  ASP D C   1 
ATOM   5559 O O   . ASP D 1 21  ? 2.424   1.273   -53.932 1.00 15.15 ? 21  ASP D O   1 
ATOM   5560 C CB  . ASP D 1 21  ? 4.032   3.690   -54.078 1.00 14.70 ? 21  ASP D CB  1 
ATOM   5561 C CG  . ASP D 1 21  ? 5.363   3.063   -53.662 1.00 22.44 ? 21  ASP D CG  1 
ATOM   5562 O OD1 . ASP D 1 21  ? 5.581   1.868   -53.929 1.00 22.45 ? 21  ASP D OD1 1 
ATOM   5563 O OD2 . ASP D 1 21  ? 6.191   3.746   -53.029 1.00 19.10 ? 21  ASP D OD2 1 
ATOM   5564 N N   . VAL D 1 22  ? 3.522   0.609   -55.789 1.00 14.95 ? 22  VAL D N   1 
ATOM   5565 C CA  . VAL D 1 22  ? 3.312   -0.828  -55.587 1.00 16.16 ? 22  VAL D CA  1 
ATOM   5566 C C   . VAL D 1 22  ? 4.681   -1.489  -55.491 1.00 14.33 ? 22  VAL D C   1 
ATOM   5567 O O   . VAL D 1 22  ? 5.428   -1.511  -56.476 1.00 14.78 ? 22  VAL D O   1 
ATOM   5568 C CB  . VAL D 1 22  ? 2.480   -1.440  -56.718 1.00 11.96 ? 22  VAL D CB  1 
ATOM   5569 C CG1 . VAL D 1 22  ? 2.355   -2.954  -56.524 1.00 16.47 ? 22  VAL D CG1 1 
ATOM   5570 C CG2 . VAL D 1 22  ? 1.086   -0.819  -56.711 1.00 12.94 ? 22  VAL D CG2 1 
ATOM   5571 N N   . ASN D 1 23  ? 5.015   -2.029  -54.313 1.00 16.63 ? 23  ASN D N   1 
ATOM   5572 C CA  . ASN D 1 23  ? 6.333   -2.634  -54.084 1.00 17.64 ? 23  ASN D CA  1 
ATOM   5573 C C   . ASN D 1 23  ? 7.475   -1.690  -54.451 1.00 19.84 ? 23  ASN D C   1 
ATOM   5574 O O   . ASN D 1 23  ? 8.538   -2.128  -54.896 1.00 17.01 ? 23  ASN D O   1 
ATOM   5575 C CB  . ASN D 1 23  ? 6.484   -3.962  -54.840 1.00 17.66 ? 23  ASN D CB  1 
ATOM   5576 C CG  . ASN D 1 23  ? 5.850   -5.124  -54.115 1.00 17.59 ? 23  ASN D CG  1 
ATOM   5577 O OD1 . ASN D 1 23  ? 4.865   -4.968  -53.394 1.00 15.02 ? 23  ASN D OD1 1 
ATOM   5578 N ND2 . ASN D 1 23  ? 6.444   -6.310  -54.279 1.00 19.26 ? 23  ASN D ND2 1 
ATOM   5579 N N   . GLY D 1 24  ? 7.268   -0.386  -54.285 1.00 18.31 ? 24  GLY D N   1 
ATOM   5580 C CA  . GLY D 1 24  ? 8.300   0.575   -54.622 1.00 19.69 ? 24  GLY D CA  1 
ATOM   5581 C C   . GLY D 1 24  ? 8.338   1.000   -56.073 1.00 20.67 ? 24  GLY D C   1 
ATOM   5582 O O   . GLY D 1 24  ? 9.146   1.869   -56.428 1.00 19.02 ? 24  GLY D O   1 
ATOM   5583 N N   . HIS D 1 25  ? 7.517   0.401   -56.930 1.00 18.59 ? 25  HIS D N   1 
ATOM   5584 C CA  . HIS D 1 25  ? 7.346   0.866   -58.304 1.00 16.67 ? 25  HIS D CA  1 
ATOM   5585 C C   . HIS D 1 25  ? 6.320   1.983   -58.261 1.00 18.99 ? 25  HIS D C   1 
ATOM   5586 O O   . HIS D 1 25  ? 5.134   1.725   -58.046 1.00 14.14 ? 25  HIS D O   1 
ATOM   5587 C CB  . HIS D 1 25  ? 6.870   -0.270  -59.209 1.00 18.22 ? 25  HIS D CB  1 
ATOM   5588 C CG  . HIS D 1 25  ? 7.748   -1.477  -59.172 1.00 22.02 ? 25  HIS D CG  1 
ATOM   5589 N ND1 . HIS D 1 25  ? 9.043   -1.471  -59.642 1.00 26.46 ? 25  HIS D ND1 1 
ATOM   5590 C CD2 . HIS D 1 25  ? 7.543   -2.711  -58.654 1.00 19.50 ? 25  HIS D CD2 1 
ATOM   5591 C CE1 . HIS D 1 25  ? 9.580   -2.665  -59.462 1.00 23.33 ? 25  HIS D CE1 1 
ATOM   5592 N NE2 . HIS D 1 25  ? 8.694   -3.432  -58.854 1.00 22.91 ? 25  HIS D NE2 1 
ATOM   5593 N N   . LYS D 1 26  ? 6.774   3.217   -58.427 1.00 17.75 ? 26  LYS D N   1 
ATOM   5594 C CA  . LYS D 1 26  ? 5.928   4.395   -58.319 1.00 16.07 ? 26  LYS D CA  1 
ATOM   5595 C C   . LYS D 1 26  ? 5.447   4.806   -59.703 1.00 16.03 ? 26  LYS D C   1 
ATOM   5596 O O   . LYS D 1 26  ? 6.156   4.639   -60.699 1.00 15.27 ? 26  LYS D O   1 
ATOM   5597 C CB  . LYS D 1 26  ? 6.689   5.547   -57.663 1.00 16.92 ? 26  LYS D CB  1 
ATOM   5598 C CG  . LYS D 1 26  ? 7.203   5.213   -56.270 1.00 18.73 ? 26  LYS D CG  1 
ATOM   5599 C CD  . LYS D 1 26  ? 8.044   6.342   -55.716 1.00 20.97 ? 26  LYS D CD  1 
ATOM   5600 C CE  . LYS D 1 26  ? 8.512   6.013   -54.314 1.00 26.25 ? 26  LYS D CE  1 
ATOM   5601 N NZ  . LYS D 1 26  ? 9.740   6.785   -53.988 1.00 31.99 ? 26  LYS D NZ  1 
ATOM   5602 N N   . PHE D 1 27  ? 4.235   5.352   -59.759 1.00 13.63 ? 27  PHE D N   1 
ATOM   5603 C CA  . PHE D 1 27  ? 3.610   5.610   -61.050 1.00 14.92 ? 27  PHE D CA  1 
ATOM   5604 C C   . PHE D 1 27  ? 2.469   6.592   -60.857 1.00 13.38 ? 27  PHE D C   1 
ATOM   5605 O O   . PHE D 1 27  ? 1.973   6.780   -59.743 1.00 14.38 ? 27  PHE D O   1 
ATOM   5606 C CB  . PHE D 1 27  ? 3.112   4.307   -61.694 1.00 14.21 ? 27  PHE D CB  1 
ATOM   5607 C CG  . PHE D 1 27  ? 2.020   3.608   -60.912 1.00 15.63 ? 27  PHE D CG  1 
ATOM   5608 C CD1 . PHE D 1 27  ? 2.337   2.709   -59.903 1.00 15.79 ? 27  PHE D CD1 1 
ATOM   5609 C CD2 . PHE D 1 27  ? 0.680   3.827   -61.212 1.00 9.03  ? 27  PHE D CD2 1 
ATOM   5610 C CE1 . PHE D 1 27  ? 1.334   2.054   -59.179 1.00 13.80 ? 27  PHE D CE1 1 
ATOM   5611 C CE2 . PHE D 1 27  ? -0.332  3.177   -60.504 1.00 12.04 ? 27  PHE D CE2 1 
ATOM   5612 C CZ  . PHE D 1 27  ? -0.006  2.285   -59.496 1.00 15.34 ? 27  PHE D CZ  1 
ATOM   5613 N N   . SER D 1 28  ? 2.062   7.230   -61.957 1.00 13.36 ? 28  SER D N   1 
ATOM   5614 C CA  . SER D 1 28  ? 0.939   8.153   -61.926 1.00 12.82 ? 28  SER D CA  1 
ATOM   5615 C C   . SER D 1 28  ? -0.041  7.792   -63.033 1.00 11.73 ? 28  SER D C   1 
ATOM   5616 O O   . SER D 1 28  ? 0.357   7.370   -64.116 1.00 13.21 ? 28  SER D O   1 
ATOM   5617 C CB  . SER D 1 28  ? 1.411   9.611   -62.086 1.00 15.18 ? 28  SER D CB  1 
ATOM   5618 O OG  . SER D 1 28  ? 0.320   10.514  -62.021 1.00 19.21 ? 28  SER D OG  1 
ATOM   5619 N N   . VAL D 1 29  ? -1.331  7.961   -62.753 1.00 10.65 ? 29  VAL D N   1 
ATOM   5620 C CA  . VAL D 1 29  ? -2.384  7.752   -63.744 1.00 13.04 ? 29  VAL D CA  1 
ATOM   5621 C C   . VAL D 1 29  ? -3.286  8.973   -63.757 1.00 12.57 ? 29  VAL D C   1 
ATOM   5622 O O   . VAL D 1 29  ? -3.704  9.448   -62.699 1.00 15.04 ? 29  VAL D O   1 
ATOM   5623 C CB  . VAL D 1 29  ? -3.218  6.493   -63.441 1.00 11.63 ? 29  VAL D CB  1 
ATOM   5624 C CG1 . VAL D 1 29  ? -4.476  6.454   -64.337 1.00 11.91 ? 29  VAL D CG1 1 
ATOM   5625 C CG2 . VAL D 1 29  ? -2.364  5.244   -63.641 1.00 11.53 ? 29  VAL D CG2 1 
ATOM   5626 N N   . SER D 1 30  ? -3.605  9.455   -64.953 1.00 11.54 ? 30  SER D N   1 
ATOM   5627 C CA  . SER D 1 30  ? -4.550  10.537  -65.167 1.00 11.60 ? 30  SER D CA  1 
ATOM   5628 C C   . SER D 1 30  ? -5.701  10.008  -65.999 1.00 13.03 ? 30  SER D C   1 
ATOM   5629 O O   . SER D 1 30  ? -5.484  9.250   -66.946 1.00 15.83 ? 30  SER D O   1 
ATOM   5630 C CB  . SER D 1 30  ? -3.905  11.709  -65.910 1.00 17.83 ? 30  SER D CB  1 
ATOM   5631 O OG  . SER D 1 30  ? -2.987  12.394  -65.074 1.00 24.29 ? 30  SER D OG  1 
ATOM   5632 N N   . GLY D 1 31  ? -6.912  10.424  -65.666 1.00 13.42 ? 31  GLY D N   1 
ATOM   5633 C CA  . GLY D 1 31  ? -8.074  10.061  -66.450 1.00 12.76 ? 31  GLY D CA  1 
ATOM   5634 C C   . GLY D 1 31  ? -8.912  11.288  -66.729 1.00 11.25 ? 31  GLY D C   1 
ATOM   5635 O O   . GLY D 1 31  ? -8.969  12.218  -65.934 1.00 12.16 ? 31  GLY D O   1 
ATOM   5636 N N   . GLU D 1 32  ? -9.571  11.276  -67.877 1.00 10.24 ? 32  GLU D N   1 
ATOM   5637 C CA  . GLU D 1 32  ? -10.514 12.345  -68.166 1.00 13.12 ? 32  GLU D CA  1 
ATOM   5638 C C   . GLU D 1 32  ? -11.645 11.810  -69.028 1.00 12.81 ? 32  GLU D C   1 
ATOM   5639 O O   . GLU D 1 32  ? -11.474 10.855  -69.795 1.00 14.34 ? 32  GLU D O   1 
ATOM   5640 C CB  . GLU D 1 32  ? -9.818  13.548  -68.822 1.00 17.67 ? 32  GLU D CB  1 
ATOM   5641 C CG  . GLU D 1 32  ? -9.699  13.481  -70.321 1.00 24.74 ? 32  GLU D CG  1 
ATOM   5642 C CD  . GLU D 1 32  ? -9.004  14.715  -70.887 1.00 35.13 ? 32  GLU D CD  1 
ATOM   5643 O OE1 . GLU D 1 32  ? -8.112  15.266  -70.194 1.00 38.09 ? 32  GLU D OE1 1 
ATOM   5644 O OE2 . GLU D 1 32  ? -9.325  15.106  -72.035 1.00 44.44 ? 32  GLU D OE2 1 
ATOM   5645 N N   . GLY D 1 33  ? -12.811 12.419  -68.866 1.00 12.78 ? 33  GLY D N   1 
ATOM   5646 C CA  . GLY D 1 33  ? -13.973 12.052  -69.636 1.00 17.06 ? 33  GLY D CA  1 
ATOM   5647 C C   . GLY D 1 33  ? -15.211 12.711  -69.074 1.00 15.32 ? 33  GLY D C   1 
ATOM   5648 O O   . GLY D 1 33  ? -15.154 13.864  -68.628 1.00 16.21 ? 33  GLY D O   1 
ATOM   5649 N N   . GLU D 1 34  ? -16.340 12.011  -69.092 1.00 14.54 ? 34  GLU D N   1 
ATOM   5650 C CA  . GLU D 1 34  ? -17.588 12.603  -68.628 1.00 15.91 ? 34  GLU D CA  1 
ATOM   5651 C C   . GLU D 1 34  ? -18.473 11.529  -68.016 1.00 14.77 ? 34  GLU D C   1 
ATOM   5652 O O   . GLU D 1 34  ? -18.363 10.345  -68.345 1.00 15.34 ? 34  GLU D O   1 
ATOM   5653 C CB  . GLU D 1 34  ? -18.366 13.307  -69.760 1.00 22.80 ? 34  GLU D CB  1 
ATOM   5654 C CG  . GLU D 1 34  ? -17.539 13.882  -70.891 1.00 28.93 ? 34  GLU D CG  1 
ATOM   5655 C CD  . GLU D 1 34  ? -18.395 14.333  -72.064 1.00 33.68 ? 34  GLU D CD  1 
ATOM   5656 O OE1 . GLU D 1 34  ? -19.093 13.488  -72.661 1.00 35.56 ? 34  GLU D OE1 1 
ATOM   5657 O OE2 . GLU D 1 34  ? -18.369 15.539  -72.380 1.00 37.28 ? 34  GLU D OE2 1 
ATOM   5658 N N   . GLY D 1 35  ? -19.371 11.972  -67.145 1.00 14.49 ? 35  GLY D N   1 
ATOM   5659 C CA  . GLY D 1 35  ? -20.382 11.102  -66.575 1.00 14.52 ? 35  GLY D CA  1 
ATOM   5660 C C   . GLY D 1 35  ? -21.761 11.688  -66.795 1.00 16.55 ? 35  GLY D C   1 
ATOM   5661 O O   . GLY D 1 35  ? -21.941 12.901  -66.842 1.00 16.54 ? 35  GLY D O   1 
ATOM   5662 N N   . ASP D 1 36  ? -22.745 10.805  -66.948 1.00 16.22 ? 36  ASP D N   1 
ATOM   5663 C CA  . ASP D 1 36  ? -24.137 11.231  -67.112 1.00 16.40 ? 36  ASP D CA  1 
ATOM   5664 C C   . ASP D 1 36  ? -25.006 10.343  -66.233 1.00 20.32 ? 36  ASP D C   1 
ATOM   5665 O O   . ASP D 1 36  ? -25.423 9.263   -66.667 1.00 17.19 ? 36  ASP D O   1 
ATOM   5666 C CB  . ASP D 1 36  ? -24.579 11.154  -68.571 1.00 20.55 ? 36  ASP D CB  1 
ATOM   5667 C CG  . ASP D 1 36  ? -25.835 11.974  -68.854 1.00 24.22 ? 36  ASP D CG  1 
ATOM   5668 O OD1 . ASP D 1 36  ? -26.556 12.336  -67.908 1.00 26.45 ? 36  ASP D OD1 1 
ATOM   5669 O OD2 . ASP D 1 36  ? -26.140 12.197  -70.038 1.00 28.77 ? 36  ASP D OD2 1 
ATOM   5670 N N   . ALA D 1 37  ? -25.308 10.813  -65.020 1.00 16.40 ? 37  ALA D N   1 
ATOM   5671 C CA  . ALA D 1 37  ? -25.987 9.951   -64.065 1.00 17.63 ? 37  ALA D CA  1 
ATOM   5672 C C   . ALA D 1 37  ? -27.410 9.647   -64.488 1.00 19.52 ? 37  ALA D C   1 
ATOM   5673 O O   . ALA D 1 37  ? -27.991 8.686   -63.987 1.00 20.14 ? 37  ALA D O   1 
ATOM   5674 C CB  . ALA D 1 37  ? -25.978 10.576  -62.671 1.00 18.95 ? 37  ALA D CB  1 
ATOM   5675 N N   . THR D 1 38  ? -27.981 10.440  -65.399 1.00 16.93 ? 38  THR D N   1 
ATOM   5676 C CA  . THR D 1 38  ? -29.287 10.102  -65.951 1.00 22.76 ? 38  THR D CA  1 
ATOM   5677 C C   . THR D 1 38  ? -29.268 8.723   -66.593 1.00 24.13 ? 38  THR D C   1 
ATOM   5678 O O   . THR D 1 38  ? -30.280 8.011   -66.574 1.00 20.95 ? 38  THR D O   1 
ATOM   5679 C CB  . THR D 1 38  ? -29.708 11.164  -66.970 1.00 25.46 ? 38  THR D CB  1 
ATOM   5680 O OG1 . THR D 1 38  ? -29.679 12.453  -66.341 1.00 30.38 ? 38  THR D OG1 1 
ATOM   5681 C CG2 . THR D 1 38  ? -31.114 10.890  -67.483 1.00 32.11 ? 38  THR D CG2 1 
ATOM   5682 N N   . TYR D 1 39  ? -28.126 8.332   -67.159 1.00 17.96 ? 39  TYR D N   1 
ATOM   5683 C CA  . TYR D 1 39  ? -27.953 7.026   -67.780 1.00 19.22 ? 39  TYR D CA  1 
ATOM   5684 C C   . TYR D 1 39  ? -27.033 6.120   -66.976 1.00 20.40 ? 39  TYR D C   1 
ATOM   5685 O O   . TYR D 1 39  ? -26.806 4.973   -67.378 1.00 20.40 ? 39  TYR D O   1 
ATOM   5686 C CB  . TYR D 1 39  ? -27.406 7.207   -69.200 1.00 19.74 ? 39  TYR D CB  1 
ATOM   5687 C CG  . TYR D 1 39  ? -28.320 8.063   -70.044 1.00 23.18 ? 39  TYR D CG  1 
ATOM   5688 C CD1 . TYR D 1 39  ? -29.539 7.577   -70.490 1.00 23.82 ? 39  TYR D CD1 1 
ATOM   5689 C CD2 . TYR D 1 39  ? -27.998 9.380   -70.329 1.00 27.45 ? 39  TYR D CD2 1 
ATOM   5690 C CE1 . TYR D 1 39  ? -30.394 8.360   -71.245 1.00 26.23 ? 39  TYR D CE1 1 
ATOM   5691 C CE2 . TYR D 1 39  ? -28.855 10.185  -71.078 1.00 32.56 ? 39  TYR D CE2 1 
ATOM   5692 C CZ  . TYR D 1 39  ? -30.051 9.663   -71.534 1.00 30.69 ? 39  TYR D CZ  1 
ATOM   5693 O OH  . TYR D 1 39  ? -30.911 10.439  -72.272 1.00 33.45 ? 39  TYR D OH  1 
ATOM   5694 N N   . GLY D 1 40  ? -26.509 6.598   -65.851 1.00 16.23 ? 40  GLY D N   1 
ATOM   5695 C CA  . GLY D 1 40  ? -25.467 5.885   -65.130 1.00 15.56 ? 40  GLY D CA  1 
ATOM   5696 C C   . GLY D 1 40  ? -24.197 5.726   -65.930 1.00 16.72 ? 40  GLY D C   1 
ATOM   5697 O O   . GLY D 1 40  ? -23.406 4.814   -65.659 1.00 16.58 ? 40  GLY D O   1 
ATOM   5698 N N   . LYS D 1 41  ? -23.967 6.607   -66.902 1.00 16.92 ? 41  LYS D N   1 
ATOM   5699 C CA  . LYS D 1 41  ? -22.951 6.418   -67.927 1.00 16.77 ? 41  LYS D CA  1 
ATOM   5700 C C   . LYS D 1 41  ? -21.643 7.116   -67.578 1.00 15.60 ? 41  LYS D C   1 
ATOM   5701 O O   . LYS D 1 41  ? -21.644 8.298   -67.226 1.00 15.56 ? 41  LYS D O   1 
ATOM   5702 C CB  . LYS D 1 41  ? -23.451 6.944   -69.272 1.00 15.31 ? 41  LYS D CB  1 
ATOM   5703 C CG  . LYS D 1 41  ? -22.561 6.580   -70.442 1.00 16.82 ? 41  LYS D CG  1 
ATOM   5704 C CD  . LYS D 1 41  ? -23.228 7.011   -71.744 1.00 23.26 ? 41  LYS D CD  1 
ATOM   5705 C CE  . LYS D 1 41  ? -22.408 6.656   -72.990 1.00 27.99 ? 41  LYS D CE  1 
ATOM   5706 N NZ  . LYS D 1 41  ? -22.009 7.879   -73.747 1.00 35.88 ? 41  LYS D NZ  1 
ATOM   5707 N N   . LEU D 1 42  ? -20.539 6.390   -67.747 1.00 15.64 ? 42  LEU D N   1 
ATOM   5708 C CA  . LEU D 1 42  ? -19.177 6.888   -67.593 1.00 15.70 ? 42  LEU D CA  1 
ATOM   5709 C C   . LEU D 1 42  ? -18.415 6.585   -68.867 1.00 16.47 ? 42  LEU D C   1 
ATOM   5710 O O   . LEU D 1 42  ? -18.374 5.434   -69.308 1.00 15.17 ? 42  LEU D O   1 
ATOM   5711 C CB  . LEU D 1 42  ? -18.455 6.206   -66.423 1.00 17.06 ? 42  LEU D CB  1 
ATOM   5712 C CG  . LEU D 1 42  ? -19.046 6.423   -65.040 1.00 19.10 ? 42  LEU D CG  1 
ATOM   5713 C CD1 . LEU D 1 42  ? -18.384 5.535   -63.994 1.00 22.16 ? 42  LEU D CD1 1 
ATOM   5714 C CD2 . LEU D 1 42  ? -18.879 7.890   -64.678 1.00 22.20 ? 42  LEU D CD2 1 
ATOM   5715 N N   . THR D 1 43  ? -17.790 7.598   -69.446 1.00 13.33 ? 43  THR D N   1 
ATOM   5716 C CA  . THR D 1 43  ? -16.857 7.383   -70.548 1.00 16.16 ? 43  THR D CA  1 
ATOM   5717 C C   . THR D 1 43  ? -15.532 8.041   -70.180 1.00 14.31 ? 43  THR D C   1 
ATOM   5718 O O   . THR D 1 43  ? -15.483 9.260   -70.000 1.00 14.35 ? 43  THR D O   1 
ATOM   5719 C CB  . THR D 1 43  ? -17.438 7.946   -71.852 1.00 17.74 ? 43  THR D CB  1 
ATOM   5720 O OG1 . THR D 1 43  ? -17.627 9.356   -71.717 1.00 22.15 ? 43  THR D OG1 1 
ATOM   5721 C CG2 . THR D 1 43  ? -18.778 7.318   -72.176 1.00 15.61 ? 43  THR D CG2 1 
ATOM   5722 N N   . LEU D 1 44  ? -14.472 7.240   -70.043 1.00 13.15 ? 44  LEU D N   1 
ATOM   5723 C CA  . LEU D 1 44  ? -13.203 7.715   -69.492 1.00 16.52 ? 44  LEU D CA  1 
ATOM   5724 C C   . LEU D 1 44  ? -12.015 7.136   -70.252 1.00 15.29 ? 44  LEU D C   1 
ATOM   5725 O O   . LEU D 1 44  ? -12.036 5.985   -70.703 1.00 13.92 ? 44  LEU D O   1 
ATOM   5726 C CB  . LEU D 1 44  ? -13.075 7.340   -67.997 1.00 16.56 ? 44  LEU D CB  1 
ATOM   5727 C CG  . LEU D 1 44  ? -14.071 8.079   -67.102 1.00 15.60 ? 44  LEU D CG  1 
ATOM   5728 C CD1 . LEU D 1 44  ? -14.284 7.341   -65.809 1.00 17.34 ? 44  LEU D CD1 1 
ATOM   5729 C CD2 . LEU D 1 44  ? -13.539 9.500   -66.835 1.00 16.11 ? 44  LEU D CD2 1 
ATOM   5730 N N   . LYS D 1 45  ? -10.963 7.942   -70.385 1.00 14.08 ? 45  LYS D N   1 
ATOM   5731 C CA  . LYS D 1 45  ? -9.689  7.458   -70.898 1.00 12.90 ? 45  LYS D CA  1 
ATOM   5732 C C   . LYS D 1 45  ? -8.624  7.756   -69.864 1.00 12.58 ? 45  LYS D C   1 
ATOM   5733 O O   . LYS D 1 45  ? -8.536  8.889   -69.386 1.00 12.02 ? 45  LYS D O   1 
ATOM   5734 C CB  . LYS D 1 45  ? -9.313  8.109   -72.236 1.00 14.02 ? 45  LYS D CB  1 
ATOM   5735 C CG  . LYS D 1 45  ? -7.929  7.660   -72.751 1.00 13.77 ? 45  LYS D CG  1 
ATOM   5736 C CD  . LYS D 1 45  ? -7.629  8.284   -74.126 1.00 16.21 ? 45  LYS D CD  1 
ATOM   5737 C CE  . LYS D 1 45  ? -6.188  8.056   -74.585 1.00 18.08 ? 45  LYS D CE  1 
ATOM   5738 N NZ  . LYS D 1 45  ? -5.905  8.793   -75.864 1.00 17.52 ? 45  LYS D NZ  1 
ATOM   5739 N N   . PHE D 1 46  ? -7.845  6.741   -69.514 1.00 12.16 ? 46  PHE D N   1 
ATOM   5740 C CA  . PHE D 1 46  ? -6.785  6.837   -68.513 1.00 12.01 ? 46  PHE D CA  1 
ATOM   5741 C C   . PHE D 1 46  ? -5.440  6.628   -69.180 1.00 11.10 ? 46  PHE D C   1 
ATOM   5742 O O   . PHE D 1 46  ? -5.303  5.762   -70.037 1.00 12.74 ? 46  PHE D O   1 
ATOM   5743 C CB  . PHE D 1 46  ? -6.946  5.782   -67.408 1.00 11.90 ? 46  PHE D CB  1 
ATOM   5744 C CG  . PHE D 1 46  ? -8.252  5.861   -66.681 1.00 13.22 ? 46  PHE D CG  1 
ATOM   5745 C CD1 . PHE D 1 46  ? -8.382  6.682   -65.570 1.00 13.66 ? 46  PHE D CD1 1 
ATOM   5746 C CD2 . PHE D 1 46  ? -9.355  5.136   -67.117 1.00 12.34 ? 46  PHE D CD2 1 
ATOM   5747 C CE1 . PHE D 1 46  ? -9.585  6.777   -64.893 1.00 10.97 ? 46  PHE D CE1 1 
ATOM   5748 C CE2 . PHE D 1 46  ? -10.561 5.222   -66.452 1.00 12.58 ? 46  PHE D CE2 1 
ATOM   5749 C CZ  . PHE D 1 46  ? -10.680 6.034   -65.335 1.00 11.72 ? 46  PHE D CZ  1 
ATOM   5750 N N   . ILE D 1 47  ? -4.440  7.390   -68.763 1.00 11.88 ? 47  ILE D N   1 
ATOM   5751 C CA  . ILE D 1 47  ? -3.078  7.216   -69.250 1.00 13.12 ? 47  ILE D CA  1 
ATOM   5752 C C   . ILE D 1 47  ? -2.148  7.043   -68.057 1.00 12.72 ? 47  ILE D C   1 
ATOM   5753 O O   . ILE D 1 47  ? -2.309  7.719   -67.038 1.00 12.58 ? 47  ILE D O   1 
ATOM   5754 C CB  . ILE D 1 47  ? -2.649  8.415   -70.120 1.00 11.32 ? 47  ILE D CB  1 
ATOM   5755 C CG1 . ILE D 1 47  ? -3.592  8.539   -71.333 1.00 14.33 ? 47  ILE D CG1 1 
ATOM   5756 C CG2 . ILE D 1 47  ? -1.170  8.296   -70.512 1.00 14.87 ? 47  ILE D CG2 1 
ATOM   5757 C CD1 . ILE D 1 47  ? -3.011  9.271   -72.497 1.00 22.26 ? 47  ILE D CD1 1 
ATOM   5758 N N   . CYS D 1 48  ? -1.192  6.121   -68.165 1.00 12.16 ? 48  CYS D N   1 
ATOM   5759 C CA  . CYS D 1 48  ? -0.066  6.117   -67.235 1.00 12.06 ? 48  CYS D CA  1 
ATOM   5760 C C   . CYS D 1 48  ? 0.903   7.190   -67.683 1.00 16.10 ? 48  CYS D C   1 
ATOM   5761 O O   . CYS D 1 48  ? 1.550   7.043   -68.722 1.00 14.27 ? 48  CYS D O   1 
ATOM   5762 C CB  . CYS D 1 48  ? 0.641   4.768   -67.188 1.00 10.61 ? 48  CYS D CB  1 
ATOM   5763 S SG  . CYS D 1 48  ? 1.954   4.735   -65.910 1.00 13.97 ? 48  CYS D SG  1 
ATOM   5764 N N   . THR D 1 49  ? 1.004   8.267   -66.905 1.00 14.04 ? 49  THR D N   1 
ATOM   5765 C CA  . THR D 1 49  ? 1.763   9.437   -67.321 1.00 16.78 ? 49  THR D CA  1 
ATOM   5766 C C   . THR D 1 49  ? 3.243   9.327   -66.984 1.00 20.92 ? 49  THR D C   1 
ATOM   5767 O O   . THR D 1 49  ? 4.010   10.227  -67.337 1.00 22.21 ? 49  THR D O   1 
ATOM   5768 C CB  . THR D 1 49  ? 1.188   10.696  -66.671 1.00 15.23 ? 49  THR D CB  1 
ATOM   5769 O OG1 . THR D 1 49  ? 0.985   10.453  -65.279 1.00 17.54 ? 49  THR D OG1 1 
ATOM   5770 C CG2 . THR D 1 49  ? -0.160  11.067  -67.305 1.00 16.92 ? 49  THR D CG2 1 
ATOM   5771 N N   . THR D 1 50  ? 3.662   8.247   -66.325 1.00 15.87 ? 50  THR D N   1 
ATOM   5772 C CA  . THR D 1 50  ? 5.046   8.084   -65.902 1.00 17.30 ? 50  THR D CA  1 
ATOM   5773 C C   . THR D 1 50  ? 5.783   7.016   -66.691 1.00 22.81 ? 50  THR D C   1 
ATOM   5774 O O   . THR D 1 50  ? 6.983   6.826   -66.480 1.00 23.48 ? 50  THR D O   1 
ATOM   5775 C CB  . THR D 1 50  ? 5.103   7.759   -64.409 1.00 19.01 ? 50  THR D CB  1 
ATOM   5776 O OG1 . THR D 1 50  ? 4.182   6.695   -64.100 1.00 13.34 ? 50  THR D OG1 1 
ATOM   5777 C CG2 . THR D 1 50  ? 4.735   9.002   -63.591 1.00 18.73 ? 50  THR D CG2 1 
ATOM   5778 N N   . GLY D 1 51  ? 5.107   6.326   -67.600 1.00 18.68 ? 51  GLY D N   1 
ATOM   5779 C CA  . GLY D 1 51  ? 5.746   5.284   -68.377 1.00 19.68 ? 51  GLY D CA  1 
ATOM   5780 C C   . GLY D 1 51  ? 4.840   4.079   -68.475 1.00 19.29 ? 51  GLY D C   1 
ATOM   5781 O O   . GLY D 1 51  ? 3.631   4.228   -68.669 1.00 16.38 ? 51  GLY D O   1 
ATOM   5782 N N   . LYS D 1 52  ? 5.411   2.888   -68.347 1.00 17.14 ? 52  LYS D N   1 
ATOM   5783 C CA  . LYS D 1 52  ? 4.631   1.660   -68.324 1.00 17.37 ? 52  LYS D CA  1 
ATOM   5784 C C   . LYS D 1 52  ? 4.018   1.438   -66.944 1.00 17.00 ? 52  LYS D C   1 
ATOM   5785 O O   . LYS D 1 52  ? 4.709   1.533   -65.925 1.00 18.15 ? 52  LYS D O   1 
ATOM   5786 C CB  . LYS D 1 52  ? 5.517   0.472   -68.703 1.00 22.98 ? 52  LYS D CB  1 
ATOM   5787 C CG  . LYS D 1 52  ? 4.769   -0.675  -69.377 1.00 28.19 ? 52  LYS D CG  1 
ATOM   5788 C CD  . LYS D 1 52  ? 4.383   -1.759  -68.393 1.00 29.35 ? 52  LYS D CD  1 
ATOM   5789 C CE  . LYS D 1 52  ? 4.034   -3.083  -69.110 1.00 31.15 ? 52  LYS D CE  1 
ATOM   5790 N NZ  . LYS D 1 52  ? 5.205   -3.666  -69.817 1.00 40.02 ? 52  LYS D NZ  1 
ATOM   5791 N N   . LEU D 1 53  ? 2.720   1.150   -66.915 1.00 16.05 ? 53  LEU D N   1 
ATOM   5792 C CA  . LEU D 1 53  ? 2.037   0.806   -65.674 1.00 14.04 ? 53  LEU D CA  1 
ATOM   5793 C C   . LEU D 1 53  ? 2.627   -0.459  -65.053 1.00 15.54 ? 53  LEU D C   1 
ATOM   5794 O O   . LEU D 1 53  ? 2.694   -1.504  -65.718 1.00 17.28 ? 53  LEU D O   1 
ATOM   5795 C CB  . LEU D 1 53  ? 0.544   0.600   -65.946 1.00 14.03 ? 53  LEU D CB  1 
ATOM   5796 C CG  . LEU D 1 53  ? -0.389  0.703   -64.749 1.00 13.38 ? 53  LEU D CG  1 
ATOM   5797 C CD1 . LEU D 1 53  ? -0.367  2.120   -64.194 1.00 11.38 ? 53  LEU D CD1 1 
ATOM   5798 C CD2 . LEU D 1 53  ? -1.826  0.301   -65.167 1.00 12.99 ? 53  LEU D CD2 1 
ATOM   5799 N N   . PRO D 1 54  ? 3.061   -0.419  -63.791 1.00 16.52 ? 54  PRO D N   1 
ATOM   5800 C CA  . PRO D 1 54  ? 3.656   -1.615  -63.191 1.00 14.87 ? 54  PRO D CA  1 
ATOM   5801 C C   . PRO D 1 54  ? 2.671   -2.674  -62.725 1.00 13.82 ? 54  PRO D C   1 
ATOM   5802 O O   . PRO D 1 54  ? 3.122   -3.713  -62.229 1.00 15.58 ? 54  PRO D O   1 
ATOM   5803 C CB  . PRO D 1 54  ? 4.473   -1.036  -62.025 1.00 17.62 ? 54  PRO D CB  1 
ATOM   5804 C CG  . PRO D 1 54  ? 3.766   0.190   -61.636 1.00 18.24 ? 54  PRO D CG  1 
ATOM   5805 C CD  . PRO D 1 54  ? 3.061   0.725   -62.865 1.00 16.46 ? 54  PRO D CD  1 
ATOM   5806 N N   . VAL D 1 55  ? 1.365   -2.455  -62.872 1.00 12.88 ? 55  VAL D N   1 
ATOM   5807 C CA  . VAL D 1 55  ? 0.333   -3.440  -62.542 1.00 12.70 ? 55  VAL D CA  1 
ATOM   5808 C C   . VAL D 1 55  ? -0.631  -3.504  -63.720 1.00 13.12 ? 55  VAL D C   1 
ATOM   5809 O O   . VAL D 1 55  ? -0.619  -2.628  -64.595 1.00 13.23 ? 55  VAL D O   1 
ATOM   5810 C CB  . VAL D 1 55  ? -0.423  -3.080  -61.237 1.00 11.76 ? 55  VAL D CB  1 
ATOM   5811 C CG1 . VAL D 1 55  ? 0.529   -2.986  -60.033 1.00 11.95 ? 55  VAL D CG1 1 
ATOM   5812 C CG2 . VAL D 1 55  ? -1.214  -1.770  -61.418 1.00 12.88 ? 55  VAL D CG2 1 
ATOM   5813 N N   . PRO D 1 56  ? -1.467  -4.537  -63.793 1.00 12.38 ? 56  PRO D N   1 
ATOM   5814 C CA  . PRO D 1 56  ? -2.430  -4.600  -64.904 1.00 11.58 ? 56  PRO D CA  1 
ATOM   5815 C C   . PRO D 1 56  ? -3.549  -3.573  -64.751 1.00 14.28 ? 56  PRO D C   1 
ATOM   5816 O O   . PRO D 1 56  ? -4.065  -3.337  -63.653 1.00 12.16 ? 56  PRO D O   1 
ATOM   5817 C CB  . PRO D 1 56  ? -2.957  -6.044  -64.854 1.00 12.58 ? 56  PRO D CB  1 
ATOM   5818 C CG  . PRO D 1 56  ? -1.979  -6.814  -63.985 1.00 15.24 ? 56  PRO D CG  1 
ATOM   5819 C CD  . PRO D 1 56  ? -1.371  -5.802  -63.042 1.00 13.70 ? 56  PRO D CD  1 
ATOM   5820 N N   . TRP D 1 57  ? -3.912  -2.956  -65.876 1.00 11.28 ? 57  TRP D N   1 
ATOM   5821 C CA  . TRP D 1 57  ? -4.999  -1.980  -65.883 1.00 11.02 ? 57  TRP D CA  1 
ATOM   5822 C C   . TRP D 1 57  ? -6.263  -2.484  -65.198 1.00 11.93 ? 57  TRP D C   1 
ATOM   5823 O O   . TRP D 1 57  ? -6.876  -1.703  -64.448 1.00 10.51 ? 57  TRP D O   1 
ATOM   5824 C CB  . TRP D 1 57  ? -5.309  -1.556  -67.336 1.00 9.89  ? 57  TRP D CB  1 
ATOM   5825 C CG  . TRP D 1 57  ? -4.401  -0.493  -67.848 1.00 13.62 ? 57  TRP D CG  1 
ATOM   5826 C CD1 . TRP D 1 57  ? -3.431  -0.637  -68.797 1.00 12.71 ? 57  TRP D CD1 1 
ATOM   5827 C CD2 . TRP D 1 57  ? -4.327  0.870   -67.404 1.00 12.11 ? 57  TRP D CD2 1 
ATOM   5828 N NE1 . TRP D 1 57  ? -2.775  0.553   -68.989 1.00 11.98 ? 57  TRP D NE1 1 
ATOM   5829 C CE2 . TRP D 1 57  ? -3.310  1.497   -68.152 1.00 12.63 ? 57  TRP D CE2 1 
ATOM   5830 C CE3 . TRP D 1 57  ? -5.035  1.619   -66.469 1.00 11.49 ? 57  TRP D CE3 1 
ATOM   5831 C CZ2 . TRP D 1 57  ? -2.975  2.850   -67.984 1.00 11.59 ? 57  TRP D CZ2 1 
ATOM   5832 C CZ3 . TRP D 1 57  ? -4.701  2.966   -66.293 1.00 10.65 ? 57  TRP D CZ3 1 
ATOM   5833 C CH2 . TRP D 1 57  ? -3.679  3.566   -67.051 1.00 12.90 ? 57  TRP D CH2 1 
ATOM   5834 N N   . PRO D 1 58  ? -6.717  -3.731  -65.404 1.00 11.79 ? 58  PRO D N   1 
ATOM   5835 C CA  . PRO D 1 58  ? -7.962  -4.153  -64.740 1.00 9.03  ? 58  PRO D CA  1 
ATOM   5836 C C   . PRO D 1 58  ? -7.899  -4.064  -63.233 1.00 10.34 ? 58  PRO D C   1 
ATOM   5837 O O   . PRO D 1 58  ? -8.941  -3.844  -62.603 1.00 10.56 ? 58  PRO D O   1 
ATOM   5838 C CB  . PRO D 1 58  ? -8.145  -5.606  -65.221 1.00 9.01  ? 58  PRO D CB  1 
ATOM   5839 C CG  . PRO D 1 58  ? -7.445  -5.646  -66.542 1.00 13.03 ? 58  PRO D CG  1 
ATOM   5840 C CD  . PRO D 1 58  ? -6.248  -4.738  -66.372 1.00 13.26 ? 58  PRO D CD  1 
ATOM   5841 N N   . THR D 1 59  ? -6.716  -4.225  -62.630 1.00 9.99  ? 59  THR D N   1 
ATOM   5842 C CA  . THR D 1 59  ? -6.635  -4.188  -61.172 1.00 11.06 ? 59  THR D CA  1 
ATOM   5843 C C   . THR D 1 59  ? -6.877  -2.797  -60.610 1.00 11.30 ? 59  THR D C   1 
ATOM   5844 O O   . THR D 1 59  ? -7.069  -2.680  -59.397 1.00 11.07 ? 59  THR D O   1 
ATOM   5845 C CB  . THR D 1 59  ? -5.283  -4.711  -60.653 1.00 10.79 ? 59  THR D CB  1 
ATOM   5846 O OG1 . THR D 1 59  ? -4.218  -3.798  -60.975 1.00 12.83 ? 59  THR D OG1 1 
ATOM   5847 C CG2 . THR D 1 59  ? -4.964  -6.079  -61.244 1.00 12.03 ? 59  THR D CG2 1 
ATOM   5848 N N   . LEU D 1 60  ? -6.867  -1.752  -61.452 1.00 11.78 ? 60  LEU D N   1 
ATOM   5849 C CA  . LEU D 1 60  ? -7.114  -0.381  -61.012 1.00 12.44 ? 60  LEU D CA  1 
ATOM   5850 C C   . LEU D 1 60  ? -8.531  0.119   -61.279 1.00 11.47 ? 60  LEU D C   1 
ATOM   5851 O O   . LEU D 1 60  ? -8.866  1.222   -60.833 1.00 11.18 ? 60  LEU D O   1 
ATOM   5852 C CB  . LEU D 1 60  ? -6.124  0.589   -61.678 1.00 10.27 ? 60  LEU D CB  1 
ATOM   5853 C CG  . LEU D 1 60  ? -4.636  0.392   -61.377 1.00 12.03 ? 60  LEU D CG  1 
ATOM   5854 C CD1 . LEU D 1 60  ? -3.799  1.455   -62.149 1.00 9.70  ? 60  LEU D CD1 1 
ATOM   5855 C CD2 . LEU D 1 60  ? -4.394  0.488   -59.864 1.00 14.28 ? 60  LEU D CD2 1 
ATOM   5856 N N   . VAL D 1 61  ? -9.375  -0.660  -61.963 1.00 10.26 ? 61  VAL D N   1 
ATOM   5857 C CA  . VAL D 1 61  ? -10.694 -0.167  -62.371 1.00 9.81  ? 61  VAL D CA  1 
ATOM   5858 C C   . VAL D 1 61  ? -11.524 0.277   -61.166 1.00 10.20 ? 61  VAL D C   1 
ATOM   5859 O O   . VAL D 1 61  ? -12.114 1.356   -61.176 1.00 10.79 ? 61  VAL D O   1 
ATOM   5860 C CB  . VAL D 1 61  ? -11.447 -1.222  -63.204 1.00 10.14 ? 61  VAL D CB  1 
ATOM   5861 C CG1 . VAL D 1 61  ? -12.920 -0.823  -63.355 1.00 10.35 ? 61  VAL D CG1 1 
ATOM   5862 C CG2 . VAL D 1 61  ? -10.820 -1.361  -64.605 1.00 9.93  ? 61  VAL D CG2 1 
ATOM   5863 N N   . THR D 1 62  ? -11.637 -0.561  -60.128 1.00 10.54 ? 62  THR D N   1 
ATOM   5864 C CA  . THR D 1 62  ? -12.483 -0.139  -59.013 1.00 10.54 ? 62  THR D CA  1 
ATOM   5865 C C   . THR D 1 62  ? -11.913 1.097   -58.310 1.00 10.42 ? 62  THR D C   1 
ATOM   5866 O O   . THR D 1 62  ? -12.668 1.909   -57.767 1.00 13.06 ? 62  THR D O   1 
ATOM   5867 C CB  . THR D 1 62  ? -12.673 -1.266  -58.007 1.00 8.05  ? 62  THR D CB  1 
ATOM   5868 O OG1 . THR D 1 62  ? -11.392 -1.775  -57.610 1.00 11.15 ? 62  THR D OG1 1 
ATOM   5869 C CG2 . THR D 1 62  ? -13.567 -2.395  -58.589 1.00 8.33  ? 62  THR D CG2 1 
ATOM   5870 N N   . THR D 1 63  ? -10.595 1.252   -58.297 1.00 10.90 ? 63  THR D N   1 
ATOM   5871 C CA  . THR D 1 63  ? -10.013 2.422   -57.640 1.00 11.30 ? 63  THR D CA  1 
ATOM   5872 C C   . THR D 1 63  ? -10.275 3.690   -58.449 1.00 10.49 ? 63  THR D C   1 
ATOM   5873 O O   . THR D 1 63  ? -10.685 4.721   -57.899 1.00 11.14 ? 63  THR D O   1 
ATOM   5874 C CB  . THR D 1 63  ? -8.513  2.213   -57.435 1.00 14.69 ? 63  THR D CB  1 
ATOM   5875 O OG1 . THR D 1 63  ? -8.284  1.087   -56.572 1.00 10.62 ? 63  THR D OG1 1 
ATOM   5876 C CG2 . THR D 1 63  ? -7.842  3.472   -56.866 1.00 10.35 ? 63  THR D CG2 1 
ATOM   5877 N N   . LEU D 1 64  ? -10.010 3.639   -59.752 1.00 10.10 ? 64  LEU D N   1 
ATOM   5878 C CA  . LEU D 1 64  ? -10.203 4.780   -60.661 1.00 10.21 ? 64  LEU D CA  1 
ATOM   5879 C C   . LEU D 1 64  ? -11.682 5.155   -60.755 1.00 11.89 ? 64  LEU D C   1 
ATOM   5880 O O   . LEU D 1 64  ? -12.054 6.311   -60.975 1.00 12.35 ? 64  LEU D O   1 
ATOM   5881 C CB  . LEU D 1 64  ? -9.647  4.436   -62.042 1.00 9.62  ? 64  LEU D CB  1 
ATOM   5882 C CG  . LEU D 1 64  ? -8.138  4.160   -62.117 1.00 11.75 ? 64  LEU D CG  1 
ATOM   5883 C CD1 . LEU D 1 64  ? -7.758  3.586   -63.490 1.00 10.21 ? 64  LEU D CD1 1 
ATOM   5884 C CD2 . LEU D 1 64  ? -7.353  5.470   -61.819 1.00 12.28 ? 64  LEU D CD2 1 
HETATM 5885 N N1  . CRO D 1 65  ? -12.530 4.081   -60.867 1.00 17.99 ? 66  CRO D N1  1 
HETATM 5886 C CA1 . CRO D 1 65  ? -13.953 4.255   -61.002 1.00 20.90 ? 66  CRO D CA1 1 
HETATM 5887 C CB1 . CRO D 1 65  ? -14.568 3.987   -62.369 1.00 23.20 ? 66  CRO D CB1 1 
HETATM 5888 C CG1 . CRO D 1 65  ? -14.129 5.014   -63.378 1.00 24.40 ? 66  CRO D CG1 1 
HETATM 5889 O OG1 . CRO D 1 65  ? -14.475 2.924   -62.751 1.00 24.62 ? 66  CRO D OG1 1 
HETATM 5890 C C1  . CRO D 1 65  ? -14.763 3.661   -59.859 1.00 21.76 ? 66  CRO D C1  1 
HETATM 5891 N N2  . CRO D 1 65  ? -15.365 2.532   -59.949 1.00 22.47 ? 66  CRO D N2  1 
HETATM 5892 N N3  . CRO D 1 65  ? -14.815 4.061   -58.634 1.00 23.25 ? 66  CRO D N3  1 
HETATM 5893 C C2  . CRO D 1 65  ? -15.424 3.159   -57.948 1.00 21.79 ? 66  CRO D C2  1 
HETATM 5894 O O2  . CRO D 1 65  ? -15.650 3.204   -56.608 1.00 18.00 ? 66  CRO D O2  1 
HETATM 5895 C CA2 . CRO D 1 65  ? -15.788 2.168   -58.798 1.00 21.45 ? 66  CRO D CA2 1 
HETATM 5896 C CA3 . CRO D 1 65  ? -14.272 5.242   -58.058 1.00 20.45 ? 66  CRO D CA3 1 
HETATM 5897 C C3  . CRO D 1 65  ? -15.265 6.407   -57.943 1.00 23.06 ? 66  CRO D C3  1 
HETATM 5898 O O3  . CRO D 1 65  ? -14.943 7.263   -57.229 1.00 21.42 ? 66  CRO D O3  1 
HETATM 5899 C CB2 . CRO D 1 65  ? -16.599 0.957   -58.367 1.00 22.13 ? 66  CRO D CB2 1 
HETATM 5900 C CG2 . CRO D 1 65  ? -16.849 -0.236  -59.263 1.00 23.78 ? 66  CRO D CG2 1 
HETATM 5901 C CD1 . CRO D 1 65  ? -16.561 -0.342  -60.604 1.00 24.17 ? 66  CRO D CD1 1 
HETATM 5902 C CD2 . CRO D 1 65  ? -17.419 -1.311  -58.646 1.00 25.01 ? 66  CRO D CD2 1 
HETATM 5903 C CE1 . CRO D 1 65  ? -16.853 -1.493  -61.276 1.00 18.44 ? 66  CRO D CE1 1 
HETATM 5904 C CE2 . CRO D 1 65  ? -17.696 -2.466  -59.295 1.00 21.78 ? 66  CRO D CE2 1 
HETATM 5905 C CZ  . CRO D 1 65  ? -17.422 -2.556  -60.621 1.00 24.82 ? 66  CRO D CZ  1 
HETATM 5906 O OH  . CRO D 1 65  ? -17.717 -3.726  -61.250 1.00 24.68 ? 66  CRO D OH  1 
ATOM   5907 N N   . VAL D 1 66  ? -16.179 6.345   -58.866 1.00 10.93 ? 68  VAL D N   1 
ATOM   5908 C CA  . VAL D 1 66  ? -17.046 7.513   -58.857 1.00 12.38 ? 68  VAL D CA  1 
ATOM   5909 C C   . VAL D 1 66  ? -18.496 7.038   -58.844 1.00 14.08 ? 68  VAL D C   1 
ATOM   5910 O O   . VAL D 1 66  ? -19.260 7.316   -59.759 1.00 13.53 ? 68  VAL D O   1 
ATOM   5911 C CB  . VAL D 1 66  ? -16.752 8.464   -60.044 1.00 10.61 ? 68  VAL D CB  1 
ATOM   5912 C CG1 . VAL D 1 66  ? -15.410 9.177   -59.849 1.00 14.44 ? 68  VAL D CG1 1 
ATOM   5913 C CG2 . VAL D 1 66  ? -16.724 7.714   -61.377 1.00 11.58 ? 68  VAL D CG2 1 
ATOM   5914 N N   . GLN D 1 67  ? -18.876 6.338   -57.771 1.00 11.33 ? 69  GLN D N   1 
ATOM   5915 C CA  . GLN D 1 67  ? -20.210 5.764   -57.701 1.00 10.85 ? 69  GLN D CA  1 
ATOM   5916 C C   . GLN D 1 67  ? -21.286 6.835   -57.581 1.00 13.33 ? 69  GLN D C   1 
ATOM   5917 O O   . GLN D 1 67  ? -22.474 6.496   -57.592 1.00 13.77 ? 69  GLN D O   1 
ATOM   5918 C CB  . GLN D 1 67  ? -20.286 4.776   -56.529 1.00 13.30 ? 69  GLN D CB  1 
ATOM   5919 C CG  . GLN D 1 67  ? -19.251 3.649   -56.698 1.00 12.43 ? 69  GLN D CG  1 
ATOM   5920 C CD  . GLN D 1 67  ? -19.030 2.872   -55.413 1.00 16.05 ? 69  GLN D CD  1 
ATOM   5921 O OE1 . GLN D 1 67  ? -18.563 3.427   -54.413 1.00 15.13 ? 69  GLN D OE1 1 
ATOM   5922 N NE2 . GLN D 1 67  ? -19.297 1.576   -55.453 1.00 16.59 ? 69  GLN D NE2 1 
ATOM   5923 N N   . CYS D 1 68  ? -20.897 8.110   -57.459 1.00 13.43 ? 70  CYS D N   1 
ATOM   5924 C CA  . CYS D 1 68  ? -21.868 9.201   -57.520 1.00 13.59 ? 70  CYS D CA  1 
ATOM   5925 C C   . CYS D 1 68  ? -22.557 9.308   -58.881 1.00 13.49 ? 70  CYS D C   1 
ATOM   5926 O O   . CYS D 1 68  ? -23.597 9.968   -58.983 1.00 16.30 ? 70  CYS D O   1 
ATOM   5927 C CB  . CYS D 1 68  ? -21.193 10.542  -57.173 1.00 15.65 ? 70  CYS D CB  1 
ATOM   5928 S SG  . CYS D 1 68  ? -19.621 10.842  -58.057 1.00 15.33 ? 70  CYS D SG  1 
ATOM   5929 N N   . PHE D 1 69  ? -22.022 8.694   -59.935 1.00 13.93 ? 71  PHE D N   1 
ATOM   5930 C CA  . PHE D 1 69  ? -22.697 8.749   -61.231 1.00 13.85 ? 71  PHE D CA  1 
ATOM   5931 C C   . PHE D 1 69  ? -23.704 7.625   -61.447 1.00 16.37 ? 71  PHE D C   1 
ATOM   5932 O O   . PHE D 1 69  ? -24.273 7.514   -62.541 1.00 16.42 ? 71  PHE D O   1 
ATOM   5933 C CB  . PHE D 1 69  ? -21.665 8.767   -62.357 1.00 17.16 ? 71  PHE D CB  1 
ATOM   5934 C CG  . PHE D 1 69  ? -20.977 10.098  -62.499 1.00 15.58 ? 71  PHE D CG  1 
ATOM   5935 C CD1 . PHE D 1 69  ? -21.612 11.143  -63.146 1.00 15.11 ? 71  PHE D CD1 1 
ATOM   5936 C CD2 . PHE D 1 69  ? -19.731 10.327  -61.919 1.00 13.26 ? 71  PHE D CD2 1 
ATOM   5937 C CE1 . PHE D 1 69  ? -21.005 12.379  -63.244 1.00 16.01 ? 71  PHE D CE1 1 
ATOM   5938 C CE2 . PHE D 1 69  ? -19.114 11.553  -62.028 1.00 14.61 ? 71  PHE D CE2 1 
ATOM   5939 C CZ  . PHE D 1 69  ? -19.749 12.589  -62.681 1.00 13.46 ? 71  PHE D CZ  1 
ATOM   5940 N N   . SER D 1 70  ? -23.968 6.805   -60.441 1.00 15.78 ? 72  SER D N   1 
ATOM   5941 C CA  . SER D 1 70  ? -24.930 5.740   -60.675 1.00 17.23 ? 72  SER D CA  1 
ATOM   5942 C C   . SER D 1 70  ? -26.318 6.313   -60.947 1.00 20.93 ? 72  SER D C   1 
ATOM   5943 O O   . SER D 1 70  ? -26.686 7.397   -60.475 1.00 19.25 ? 72  SER D O   1 
ATOM   5944 C CB  . SER D 1 70  ? -24.987 4.786   -59.492 1.00 19.57 ? 72  SER D CB  1 
ATOM   5945 O OG  . SER D 1 70  ? -25.787 5.349   -58.498 1.00 30.54 ? 72  SER D OG  1 
ATOM   5946 N N   . ARG D 1 71  ? -27.084 5.579   -61.744 1.00 18.82 ? 73  ARG D N   1 
ATOM   5947 C CA  . ARG D 1 71  ? -28.485 5.896   -61.955 1.00 21.14 ? 73  ARG D CA  1 
ATOM   5948 C C   . ARG D 1 71  ? -29.257 5.422   -60.721 1.00 22.75 ? 73  ARG D C   1 
ATOM   5949 O O   . ARG D 1 71  ? -29.052 4.300   -60.254 1.00 21.58 ? 73  ARG D O   1 
ATOM   5950 C CB  . ARG D 1 71  ? -28.963 5.204   -63.239 1.00 20.98 ? 73  ARG D CB  1 
ATOM   5951 C CG  . ARG D 1 71  ? -30.391 5.422   -63.610 1.00 26.54 ? 73  ARG D CG  1 
ATOM   5952 C CD  . ARG D 1 71  ? -30.690 5.080   -65.089 1.00 22.91 ? 73  ARG D CD  1 
ATOM   5953 N NE  . ARG D 1 71  ? -30.719 3.641   -65.344 1.00 21.44 ? 73  ARG D NE  1 
ATOM   5954 C CZ  . ARG D 1 71  ? -31.843 2.936   -65.380 1.00 25.63 ? 73  ARG D CZ  1 
ATOM   5955 N NH1 . ARG D 1 71  ? -33.003 3.479   -65.042 1.00 24.33 ? 73  ARG D NH1 1 
ATOM   5956 N NH2 . ARG D 1 71  ? -31.797 1.645   -65.716 1.00 18.63 ? 73  ARG D NH2 1 
ATOM   5957 N N   . TYR D 1 72  ? -30.090 6.291   -60.146 1.00 27.36 ? 74  TYR D N   1 
ATOM   5958 C CA  . TYR D 1 72  ? -30.897 5.887   -58.995 1.00 27.79 ? 74  TYR D CA  1 
ATOM   5959 C C   . TYR D 1 72  ? -32.375 6.032   -59.343 1.00 30.69 ? 74  TYR D C   1 
ATOM   5960 O O   . TYR D 1 72  ? -32.751 6.928   -60.100 1.00 32.18 ? 74  TYR D O   1 
ATOM   5961 C CB  . TYR D 1 72  ? -30.623 6.705   -57.713 1.00 30.27 ? 74  TYR D CB  1 
ATOM   5962 C CG  . TYR D 1 72  ? -29.525 6.186   -56.779 1.00 30.33 ? 74  TYR D CG  1 
ATOM   5963 C CD1 . TYR D 1 72  ? -28.184 6.405   -57.054 1.00 27.07 ? 74  TYR D CD1 1 
ATOM   5964 C CD2 . TYR D 1 72  ? -29.838 5.433   -55.643 1.00 33.74 ? 74  TYR D CD2 1 
ATOM   5965 C CE1 . TYR D 1 72  ? -27.182 5.937   -56.200 1.00 29.55 ? 74  TYR D CE1 1 
ATOM   5966 C CE2 . TYR D 1 72  ? -28.835 4.941   -54.795 1.00 31.00 ? 74  TYR D CE2 1 
ATOM   5967 C CZ  . TYR D 1 72  ? -27.504 5.196   -55.088 1.00 29.69 ? 74  TYR D CZ  1 
ATOM   5968 O OH  . TYR D 1 72  ? -26.476 4.731   -54.285 1.00 26.25 ? 74  TYR D OH  1 
ATOM   5969 N N   . PRO D 1 73  ? -33.229 5.202   -58.786 1.00 29.60 ? 75  PRO D N   1 
ATOM   5970 C CA  . PRO D 1 73  ? -34.657 5.346   -59.001 1.00 40.06 ? 75  PRO D CA  1 
ATOM   5971 C C   . PRO D 1 73  ? -35.187 6.491   -58.162 1.00 44.62 ? 75  PRO D C   1 
ATOM   5972 O O   . PRO D 1 73  ? -34.680 6.732   -57.109 1.00 43.42 ? 75  PRO D O   1 
ATOM   5973 C CB  . PRO D 1 73  ? -35.227 4.006   -58.551 1.00 38.76 ? 75  PRO D CB  1 
ATOM   5974 C CG  . PRO D 1 73  ? -34.315 3.440   -57.766 1.00 41.14 ? 75  PRO D CG  1 
ATOM   5975 C CD  . PRO D 1 73  ? -32.953 3.955   -58.088 1.00 34.89 ? 75  PRO D CD  1 
ATOM   5976 N N   . ASP D 1 74  ? -36.150 7.240   -58.645 1.00 47.82 ? 76  ASP D N   1 
ATOM   5977 C CA  . ASP D 1 74  ? -36.530 8.420   -57.888 1.00 51.67 ? 76  ASP D CA  1 
ATOM   5978 C C   . ASP D 1 74  ? -37.023 8.188   -56.482 1.00 51.56 ? 76  ASP D C   1 
ATOM   5979 O O   . ASP D 1 74  ? -36.895 9.063   -55.676 1.00 56.81 ? 76  ASP D O   1 
ATOM   5980 C CB  . ASP D 1 74  ? -37.424 9.384   -58.677 1.00 53.92 ? 76  ASP D CB  1 
ATOM   5981 C CG  . ASP D 1 74  ? -38.396 8.682   -59.511 1.00 56.21 ? 76  ASP D CG  1 
ATOM   5982 O OD1 . ASP D 1 74  ? -38.963 9.274   -60.440 1.00 57.17 ? 76  ASP D OD1 1 
ATOM   5983 O OD2 . ASP D 1 74  ? -38.615 7.514   -59.198 1.00 59.18 ? 76  ASP D OD2 1 
ATOM   5984 N N   . HIS D 1 75  ? -37.542 7.026   -56.148 1.00 54.39 ? 77  HIS D N   1 
ATOM   5985 C CA  . HIS D 1 75  ? -37.887 6.816   -54.742 1.00 60.16 ? 77  HIS D CA  1 
ATOM   5986 C C   . HIS D 1 75  ? -36.669 6.629   -53.879 1.00 58.65 ? 77  HIS D C   1 
ATOM   5987 O O   . HIS D 1 75  ? -36.685 6.909   -52.708 1.00 63.18 ? 77  HIS D O   1 
ATOM   5988 C CB  . HIS D 1 75  ? -38.828 5.670   -54.513 1.00 62.10 ? 77  HIS D CB  1 
ATOM   5989 C CG  . HIS D 1 75  ? -38.171 4.345   -54.519 1.00 62.60 ? 77  HIS D CG  1 
ATOM   5990 N ND1 . HIS D 1 75  ? -38.245 3.497   -55.598 1.00 64.69 ? 77  HIS D ND1 1 
ATOM   5991 C CD2 . HIS D 1 75  ? -37.480 3.690   -53.567 1.00 62.42 ? 77  HIS D CD2 1 
ATOM   5992 C CE1 . HIS D 1 75  ? -37.599 2.380   -55.320 1.00 65.18 ? 77  HIS D CE1 1 
ATOM   5993 N NE2 . HIS D 1 75  ? -37.116 2.478   -54.095 1.00 63.11 ? 77  HIS D NE2 1 
ATOM   5994 N N   . MET D 1 76  ? -35.592 6.193   -54.481 1.00 56.67 ? 78  MET D N   1 
ATOM   5995 C CA  . MET D 1 76  ? -34.390 6.072   -53.721 1.00 55.87 ? 78  MET D CA  1 
ATOM   5996 C C   . MET D 1 76  ? -33.563 7.315   -53.784 1.00 53.66 ? 78  MET D C   1 
ATOM   5997 O O   . MET D 1 76  ? -32.565 7.379   -53.151 1.00 52.24 ? 78  MET D O   1 
ATOM   5998 C CB  . MET D 1 76  ? -33.593 4.863   -54.177 1.00 52.62 ? 78  MET D CB  1 
ATOM   5999 C CG  . MET D 1 76  ? -34.200 3.563   -53.684 1.00 56.28 ? 78  MET D CG  1 
ATOM   6000 S SD  . MET D 1 76  ? -33.336 2.092   -54.169 1.00 53.71 ? 78  MET D SD  1 
ATOM   6001 C CE  . MET D 1 76  ? -31.769 2.448   -53.512 1.00 41.80 ? 78  MET D CE  1 
ATOM   6002 N N   . LYS D 1 77  ? -33.975 8.311   -54.546 1.00 55.90 ? 79  LYS D N   1 
ATOM   6003 C CA  . LYS D 1 77  ? -33.173 9.510   -54.654 1.00 54.74 ? 79  LYS D CA  1 
ATOM   6004 C C   . LYS D 1 77  ? -32.827 10.600  -53.677 1.00 57.94 ? 79  LYS D C   1 
ATOM   6005 O O   . LYS D 1 77  ? -32.250 11.609  -54.016 1.00 61.10 ? 79  LYS D O   1 
ATOM   6006 C CB  . LYS D 1 77  ? -33.552 10.395  -55.863 1.00 54.29 ? 79  LYS D CB  1 
ATOM   6007 C CG  . LYS D 1 77  ? -33.074 9.899   -57.251 1.00 50.37 ? 79  LYS D CG  1 
ATOM   6008 C CD  . LYS D 1 77  ? -33.974 10.352  -58.433 1.00 52.50 ? 79  LYS D CD  1 
ATOM   6009 C CE  . LYS D 1 77  ? -33.340 10.023  -59.816 1.00 48.13 ? 79  LYS D CE  1 
ATOM   6010 N NZ  . LYS D 1 77  ? -33.630 11.031  -60.888 1.00 52.39 ? 79  LYS D NZ  1 
ATOM   6011 N N   . ARG D 1 78  ? -33.135 10.180  -52.455 1.00 56.99 ? 80  ARG D N   1 
ATOM   6012 C CA  . ARG D 1 78  ? -32.779 10.816  -51.206 1.00 59.81 ? 80  ARG D CA  1 
ATOM   6013 C C   . ARG D 1 78  ? -32.068 9.778   -50.338 1.00 55.92 ? 80  ARG D C   1 
ATOM   6014 O O   . ARG D 1 78  ? -31.488 10.079  -49.349 1.00 55.92 ? 80  ARG D O   1 
ATOM   6015 C CB  . ARG D 1 78  ? -34.056 11.307  -50.550 1.00 60.53 ? 80  ARG D CB  1 
ATOM   6016 C CG  . ARG D 1 78  ? -34.549 12.592  -51.124 1.00 60.37 ? 80  ARG D CG  1 
ATOM   6017 C CD  . ARG D 1 78  ? -33.885 13.776  -50.486 1.00 65.35 ? 80  ARG D CD  1 
ATOM   6018 N NE  . ARG D 1 78  ? -34.807 14.432  -49.566 1.00 65.87 ? 80  ARG D NE  1 
ATOM   6019 C CZ  . ARG D 1 78  ? -35.650 13.802  -48.739 1.00 69.35 ? 80  ARG D CZ  1 
ATOM   6020 N NH1 . ARG D 1 78  ? -36.443 14.515  -47.941 1.00 69.58 ? 80  ARG D NH1 1 
ATOM   6021 N NH2 . ARG D 1 78  ? -35.708 12.471  -48.713 1.00 67.15 ? 80  ARG D NH2 1 
ATOM   6022 N N   . HIS D 1 79  ? -32.093 8.532   -50.736 1.00 55.22 ? 81  HIS D N   1 
ATOM   6023 C CA  . HIS D 1 79  ? -31.162 7.599   -50.157 1.00 52.11 ? 81  HIS D CA  1 
ATOM   6024 C C   . HIS D 1 79  ? -29.719 8.001   -50.518 1.00 47.00 ? 81  HIS D C   1 
ATOM   6025 O O   . HIS D 1 79  ? -28.836 7.801   -49.726 1.00 48.86 ? 81  HIS D O   1 
ATOM   6026 C CB  . HIS D 1 79  ? -31.421 6.154   -50.642 1.00 54.43 ? 81  HIS D CB  1 
ATOM   6027 C CG  . HIS D 1 79  ? -32.305 5.338   -49.740 1.00 55.95 ? 81  HIS D CG  1 
ATOM   6028 N ND1 . HIS D 1 79  ? -32.490 5.625   -48.404 1.00 53.94 ? 81  HIS D ND1 1 
ATOM   6029 C CD2 . HIS D 1 79  ? -33.081 4.267   -49.997 1.00 60.37 ? 81  HIS D CD2 1 
ATOM   6030 C CE1 . HIS D 1 79  ? -33.352 4.770   -47.881 1.00 56.88 ? 81  HIS D CE1 1 
ATOM   6031 N NE2 . HIS D 1 79  ? -33.707 3.924   -48.827 1.00 61.37 ? 81  HIS D NE2 1 
ATOM   6032 N N   . ASP D 1 80  ? -29.517 8.520   -51.724 1.00 43.50 ? 82  ASP D N   1 
ATOM   6033 C CA  . ASP D 1 80  ? -28.252 8.755   -52.457 1.00 30.78 ? 82  ASP D CA  1 
ATOM   6034 C C   . ASP D 1 80  ? -27.269 9.481   -51.557 1.00 28.71 ? 82  ASP D C   1 
ATOM   6035 O O   . ASP D 1 80  ? -27.389 10.646  -51.334 1.00 26.21 ? 82  ASP D O   1 
ATOM   6036 C CB  . ASP D 1 80  ? -28.477 9.330   -53.860 1.00 30.51 ? 82  ASP D CB  1 
ATOM   6037 C CG  . ASP D 1 80  ? -27.320 9.032   -54.825 1.00 29.88 ? 82  ASP D CG  1 
ATOM   6038 O OD1 . ASP D 1 80  ? -26.215 8.811   -54.375 1.00 26.34 ? 82  ASP D OD1 1 
ATOM   6039 O OD2 . ASP D 1 80  ? -27.551 9.080   -56.026 1.00 27.78 ? 82  ASP D OD2 1 
ATOM   6040 N N   . PHE D 1 81  ? -26.260 8.761   -51.127 1.00 25.10 ? 83  PHE D N   1 
ATOM   6041 C CA  . PHE D 1 81  ? -25.272 9.291   -50.236 1.00 22.48 ? 83  PHE D CA  1 
ATOM   6042 C C   . PHE D 1 81  ? -24.236 9.962   -51.129 1.00 20.48 ? 83  PHE D C   1 
ATOM   6043 O O   . PHE D 1 81  ? -23.785 11.019  -50.861 1.00 17.72 ? 83  PHE D O   1 
ATOM   6044 C CB  . PHE D 1 81  ? -24.602 8.197   -49.410 1.00 19.46 ? 83  PHE D CB  1 
ATOM   6045 C CG  . PHE D 1 81  ? -23.237 8.542   -48.932 1.00 21.76 ? 83  PHE D CG  1 
ATOM   6046 C CD1 . PHE D 1 81  ? -23.059 9.257   -47.786 1.00 21.96 ? 83  PHE D CD1 1 
ATOM   6047 C CD2 . PHE D 1 81  ? -22.140 8.143   -49.610 1.00 18.92 ? 83  PHE D CD2 1 
ATOM   6048 C CE1 . PHE D 1 81  ? -21.831 9.546   -47.361 1.00 22.93 ? 83  PHE D CE1 1 
ATOM   6049 C CE2 . PHE D 1 81  ? -20.906 8.447   -49.194 1.00 19.29 ? 83  PHE D CE2 1 
ATOM   6050 C CZ  . PHE D 1 81  ? -20.754 9.150   -48.076 1.00 21.88 ? 83  PHE D CZ  1 
ATOM   6051 N N   . PHE D 1 82  ? -23.852 9.282   -52.190 1.00 15.69 ? 84  PHE D N   1 
ATOM   6052 C CA  . PHE D 1 82  ? -22.743 9.719   -52.999 1.00 16.49 ? 84  PHE D CA  1 
ATOM   6053 C C   . PHE D 1 82  ? -22.994 11.094  -53.616 1.00 18.52 ? 84  PHE D C   1 
ATOM   6054 O O   . PHE D 1 82  ? -22.121 11.894  -53.673 1.00 17.88 ? 84  PHE D O   1 
ATOM   6055 C CB  . PHE D 1 82  ? -22.412 8.713   -54.075 1.00 13.94 ? 84  PHE D CB  1 
ATOM   6056 C CG  . PHE D 1 82  ? -22.131 7.337   -53.565 1.00 17.39 ? 84  PHE D CG  1 
ATOM   6057 C CD1 . PHE D 1 82  ? -20.910 7.008   -53.078 1.00 17.99 ? 84  PHE D CD1 1 
ATOM   6058 C CD2 . PHE D 1 82  ? -23.083 6.364   -53.588 1.00 17.10 ? 84  PHE D CD2 1 
ATOM   6059 C CE1 . PHE D 1 82  ? -20.653 5.772   -52.643 1.00 15.42 ? 84  PHE D CE1 1 
ATOM   6060 C CE2 . PHE D 1 82  ? -22.798 5.118   -53.133 1.00 18.50 ? 84  PHE D CE2 1 
ATOM   6061 C CZ  . PHE D 1 82  ? -21.601 4.847   -52.661 1.00 16.90 ? 84  PHE D CZ  1 
ATOM   6062 N N   . LYS D 1 83  ? -24.194 11.306  -54.104 1.00 16.65 ? 85  LYS D N   1 
ATOM   6063 C CA  . LYS D 1 83  ? -24.530 12.576  -54.689 1.00 17.80 ? 85  LYS D CA  1 
ATOM   6064 C C   . LYS D 1 83  ? -24.830 13.645  -53.645 1.00 20.29 ? 85  LYS D C   1 
ATOM   6065 O O   . LYS D 1 83  ? -24.476 14.759  -53.815 1.00 21.80 ? 85  LYS D O   1 
ATOM   6066 C CB  . LYS D 1 83  ? -25.712 12.456  -55.623 1.00 16.93 ? 85  LYS D CB  1 
ATOM   6067 C CG  . LYS D 1 83  ? -25.459 11.766  -56.963 1.00 18.75 ? 85  LYS D CG  1 
ATOM   6068 C CD  . LYS D 1 83  ? -26.726 11.694  -57.803 1.00 16.73 ? 85  LYS D CD  1 
ATOM   6069 C CE  . LYS D 1 83  ? -26.587 10.786  -58.993 1.00 19.85 ? 85  LYS D CE  1 
ATOM   6070 N NZ  . LYS D 1 83  ? -26.237 9.458   -58.629 1.00 18.66 ? 85  LYS D NZ  1 
ATOM   6071 N N   . SER D 1 84  ? -25.489 13.278  -52.578 1.00 19.02 ? 86  SER D N   1 
ATOM   6072 C CA  . SER D 1 84  ? -25.857 14.272  -51.570 1.00 22.34 ? 86  SER D CA  1 
ATOM   6073 C C   . SER D 1 84  ? -24.641 14.801  -50.813 1.00 25.06 ? 86  SER D C   1 
ATOM   6074 O O   . SER D 1 84  ? -24.711 15.896  -50.247 1.00 25.92 ? 86  SER D O   1 
ATOM   6075 C CB  . SER D 1 84  ? -26.898 13.690  -50.604 1.00 27.58 ? 86  SER D CB  1 
ATOM   6076 O OG  . SER D 1 84  ? -26.288 13.053  -49.491 1.00 38.54 ? 86  SER D OG  1 
ATOM   6077 N N   . ALA D 1 85  ? -23.519 14.071  -50.817 1.00 19.65 ? 87  ALA D N   1 
ATOM   6078 C CA  . ALA D 1 85  ? -22.286 14.611  -50.254 1.00 20.58 ? 87  ALA D CA  1 
ATOM   6079 C C   . ALA D 1 85  ? -21.691 15.748  -51.090 1.00 20.26 ? 87  ALA D C   1 
ATOM   6080 O O   . ALA D 1 85  ? -20.819 16.476  -50.593 1.00 18.83 ? 87  ALA D O   1 
ATOM   6081 C CB  . ALA D 1 85  ? -21.246 13.498  -50.106 1.00 17.68 ? 87  ALA D CB  1 
ATOM   6082 N N   . MET D 1 86  ? -22.121 15.925  -52.349 1.00 14.87 ? 88  MET D N   1 
ATOM   6083 C CA  . MET D 1 86  ? -21.442 16.982  -53.083 1.00 16.19 ? 88  MET D CA  1 
ATOM   6084 C C   . MET D 1 86  ? -22.073 18.348  -52.844 1.00 19.97 ? 88  MET D C   1 
ATOM   6085 O O   . MET D 1 86  ? -23.226 18.449  -52.425 1.00 20.50 ? 88  MET D O   1 
ATOM   6086 C CB  . MET D 1 86  ? -21.433 16.680  -54.573 1.00 19.91 ? 88  MET D CB  1 
ATOM   6087 C CG  . MET D 1 86  ? -21.105 15.262  -54.903 1.00 14.83 ? 88  MET D CG  1 
ATOM   6088 S SD  . MET D 1 86  ? -19.299 15.264  -54.844 1.00 15.18 ? 88  MET D SD  1 
ATOM   6089 C CE  . MET D 1 86  ? -18.988 13.538  -54.427 1.00 17.22 ? 88  MET D CE  1 
ATOM   6090 N N   . PRO D 1 87  ? -21.350 19.438  -53.144 1.00 19.47 ? 89  PRO D N   1 
ATOM   6091 C CA  . PRO D 1 87  ? -20.048 19.554  -53.826 1.00 17.98 ? 89  PRO D CA  1 
ATOM   6092 C C   . PRO D 1 87  ? -18.832 19.240  -52.953 1.00 19.23 ? 89  PRO D C   1 
ATOM   6093 O O   . PRO D 1 87  ? -17.747 19.012  -53.494 1.00 16.42 ? 89  PRO D O   1 
ATOM   6094 C CB  . PRO D 1 87  ? -20.022 21.026  -54.256 1.00 20.72 ? 89  PRO D CB  1 
ATOM   6095 C CG  . PRO D 1 87  ? -20.820 21.701  -53.201 1.00 20.65 ? 89  PRO D CG  1 
ATOM   6096 C CD  . PRO D 1 87  ? -21.938 20.764  -52.876 1.00 23.61 ? 89  PRO D CD  1 
ATOM   6097 N N   . GLU D 1 88  ? -19.014 19.237  -51.630 1.00 17.80 ? 90  GLU D N   1 
ATOM   6098 C CA  . GLU D 1 88  ? -17.883 19.061  -50.724 1.00 20.56 ? 90  GLU D CA  1 
ATOM   6099 C C   . GLU D 1 88  ? -17.263 17.674  -50.862 1.00 20.59 ? 90  GLU D C   1 
ATOM   6100 O O   . GLU D 1 88  ? -16.035 17.523  -50.751 1.00 17.99 ? 90  GLU D O   1 
ATOM   6101 C CB  . GLU D 1 88  ? -18.317 19.318  -49.280 1.00 23.90 ? 90  GLU D CB  1 
ATOM   6102 C CG  . GLU D 1 88  ? -18.964 20.686  -49.064 1.00 27.64 ? 90  GLU D CG  1 
ATOM   6103 C CD  . GLU D 1 88  ? -20.460 20.759  -49.404 1.00 31.40 ? 90  GLU D CD  1 
ATOM   6104 O OE1 . GLU D 1 88  ? -21.041 19.786  -49.939 1.00 24.67 ? 90  GLU D OE1 1 
ATOM   6105 O OE2 . GLU D 1 88  ? -21.052 21.843  -49.188 1.00 35.53 ? 90  GLU D OE2 1 
ATOM   6106 N N   . GLY D 1 89  ? -18.079 16.666  -51.107 1.00 18.94 ? 91  GLY D N   1 
ATOM   6107 C CA  . GLY D 1 89  ? -17.571 15.380  -51.541 1.00 16.66 ? 91  GLY D CA  1 
ATOM   6108 C C   . GLY D 1 89  ? -17.436 14.381  -50.414 1.00 19.22 ? 91  GLY D C   1 
ATOM   6109 O O   . GLY D 1 89  ? -17.951 14.553  -49.303 1.00 16.58 ? 91  GLY D O   1 
ATOM   6110 N N   . TYR D 1 90  ? -16.729 13.294  -50.725 1.00 15.52 ? 92  TYR D N   1 
ATOM   6111 C CA  . TYR D 1 90  ? -16.561 12.213  -49.766 1.00 15.93 ? 92  TYR D CA  1 
ATOM   6112 C C   . TYR D 1 90  ? -15.180 11.606  -49.901 1.00 15.06 ? 92  TYR D C   1 
ATOM   6113 O O   . TYR D 1 90  ? -14.527 11.702  -50.948 1.00 14.40 ? 92  TYR D O   1 
ATOM   6114 C CB  . TYR D 1 90  ? -17.648 11.141  -49.923 1.00 13.91 ? 92  TYR D CB  1 
ATOM   6115 C CG  . TYR D 1 90  ? -17.759 10.504  -51.306 1.00 16.24 ? 92  TYR D CG  1 
ATOM   6116 C CD1 . TYR D 1 90  ? -16.900 9.477   -51.718 1.00 15.11 ? 92  TYR D CD1 1 
ATOM   6117 C CD2 . TYR D 1 90  ? -18.730 10.928  -52.192 1.00 15.67 ? 92  TYR D CD2 1 
ATOM   6118 C CE1 . TYR D 1 90  ? -17.031 8.891   -52.993 1.00 13.81 ? 92  TYR D CE1 1 
ATOM   6119 C CE2 . TYR D 1 90  ? -18.879 10.335  -53.457 1.00 14.64 ? 92  TYR D CE2 1 
ATOM   6120 C CZ  . TYR D 1 90  ? -18.028 9.332   -53.852 1.00 13.89 ? 92  TYR D CZ  1 
ATOM   6121 O OH  . TYR D 1 90  ? -18.186 8.772   -55.112 1.00 14.62 ? 92  TYR D OH  1 
ATOM   6122 N N   . VAL D 1 91  ? -14.728 11.017  -48.804 1.00 16.50 ? 93  VAL D N   1 
ATOM   6123 C CA  . VAL D 1 91  ? -13.505 10.227  -48.792 1.00 14.74 ? 93  VAL D CA  1 
ATOM   6124 C C   . VAL D 1 91  ? -13.893 8.788   -49.095 1.00 14.90 ? 93  VAL D C   1 
ATOM   6125 O O   . VAL D 1 91  ? -14.894 8.282   -48.574 1.00 15.46 ? 93  VAL D O   1 
ATOM   6126 C CB  . VAL D 1 91  ? -12.782 10.332  -47.433 1.00 18.26 ? 93  VAL D CB  1 
ATOM   6127 C CG1 . VAL D 1 91  ? -11.611 9.352   -47.373 1.00 15.13 ? 93  VAL D CG1 1 
ATOM   6128 C CG2 . VAL D 1 91  ? -12.316 11.771  -47.167 1.00 20.66 ? 93  VAL D CG2 1 
ATOM   6129 N N   . GLN D 1 92  ? -13.117 8.127   -49.952 1.00 12.98 ? 94  GLN D N   1 
ATOM   6130 C CA  . GLN D 1 92  ? -13.317 6.714   -50.270 1.00 13.00 ? 94  GLN D CA  1 
ATOM   6131 C C   . GLN D 1 92  ? -12.035 5.972   -49.956 1.00 12.38 ? 94  GLN D C   1 
ATOM   6132 O O   . GLN D 1 92  ? -10.997 6.269   -50.549 1.00 13.17 ? 94  GLN D O   1 
ATOM   6133 C CB  . GLN D 1 92  ? -13.670 6.502   -51.744 1.00 12.97 ? 94  GLN D CB  1 
ATOM   6134 C CG  . GLN D 1 92  ? -13.917 5.033   -52.083 1.00 12.64 ? 94  GLN D CG  1 
ATOM   6135 C CD  . GLN D 1 92  ? -14.780 4.883   -53.300 1.00 14.43 ? 94  GLN D CD  1 
ATOM   6136 O OE1 . GLN D 1 92  ? -15.928 5.312   -53.293 1.00 13.97 ? 94  GLN D OE1 1 
ATOM   6137 N NE2 . GLN D 1 92  ? -14.264 4.201   -54.329 1.00 13.18 ? 94  GLN D NE2 1 
ATOM   6138 N N   . GLU D 1 93  ? -12.113 5.002   -49.043 1.00 13.76 ? 95  GLU D N   1 
ATOM   6139 C CA  . GLU D 1 93  ? -10.968 4.216   -48.611 1.00 12.91 ? 95  GLU D CA  1 
ATOM   6140 C C   . GLU D 1 93  ? -11.220 2.742   -48.909 1.00 15.04 ? 95  GLU D C   1 
ATOM   6141 O O   . GLU D 1 93  ? -12.331 2.243   -48.713 1.00 12.37 ? 95  GLU D O   1 
ATOM   6142 C CB  . GLU D 1 93  ? -10.733 4.404   -47.108 1.00 18.24 ? 95  GLU D CB  1 
ATOM   6143 C CG  . GLU D 1 93  ? -9.878  5.590   -46.785 1.00 17.13 ? 95  GLU D CG  1 
ATOM   6144 C CD  . GLU D 1 93  ? -10.061 6.077   -45.363 1.00 29.06 ? 95  GLU D CD  1 
ATOM   6145 O OE1 . GLU D 1 93  ? -11.176 5.971   -44.788 1.00 28.49 ? 95  GLU D OE1 1 
ATOM   6146 O OE2 . GLU D 1 93  ? -9.040  6.500   -44.801 1.00 30.01 ? 95  GLU D OE2 1 
ATOM   6147 N N   . ARG D 1 94  ? -10.194 2.044   -49.386 1.00 12.10 ? 96  ARG D N   1 
ATOM   6148 C CA  . ARG D 1 94  ? -10.333 0.621   -49.627 1.00 11.68 ? 96  ARG D CA  1 
ATOM   6149 C C   . ARG D 1 94  ? -9.073  -0.117  -49.205 1.00 12.77 ? 96  ARG D C   1 
ATOM   6150 O O   . ARG D 1 94  ? -7.972  0.439   -49.196 1.00 11.94 ? 96  ARG D O   1 
ATOM   6151 C CB  . ARG D 1 94  ? -10.615 0.297   -51.114 1.00 11.55 ? 96  ARG D CB  1 
ATOM   6152 C CG  . ARG D 1 94  ? -12.037 0.694   -51.573 1.00 12.18 ? 96  ARG D CG  1 
ATOM   6153 C CD  . ARG D 1 94  ? -12.570 -0.301  -52.597 1.00 11.42 ? 96  ARG D CD  1 
ATOM   6154 N NE  . ARG D 1 94  ? -13.836 0.106   -53.198 1.00 10.90 ? 96  ARG D NE  1 
ATOM   6155 C CZ  . ARG D 1 94  ? -13.914 0.746   -54.359 1.00 9.47  ? 96  ARG D CZ  1 
ATOM   6156 N NH1 . ARG D 1 94  ? -12.827 1.194   -54.966 1.00 10.06 ? 96  ARG D NH1 1 
ATOM   6157 N NH2 . ARG D 1 94  ? -15.107 0.935   -54.923 1.00 10.73 ? 96  ARG D NH2 1 
ATOM   6158 N N   . THR D 1 95  ? -9.265  -1.389  -48.865 1.00 11.62 ? 97  THR D N   1 
ATOM   6159 C CA  . THR D 1 95  ? -8.215  -2.395  -48.878 1.00 13.01 ? 97  THR D CA  1 
ATOM   6160 C C   . THR D 1 95  ? -8.642  -3.467  -49.861 1.00 13.12 ? 97  THR D C   1 
ATOM   6161 O O   . THR D 1 95  ? -9.792  -3.908  -49.830 1.00 11.34 ? 97  THR D O   1 
ATOM   6162 C CB  . THR D 1 95  ? -8.006  -2.994  -47.488 1.00 14.59 ? 97  THR D CB  1 
ATOM   6163 O OG1 . THR D 1 95  ? -7.810  -1.926  -46.557 1.00 12.46 ? 97  THR D OG1 1 
ATOM   6164 C CG2 . THR D 1 95  ? -6.787  -3.923  -47.482 1.00 14.30 ? 97  THR D CG2 1 
ATOM   6165 N N   . ILE D 1 96  ? -7.733  -3.863  -50.742 1.00 11.77 ? 98  ILE D N   1 
ATOM   6166 C CA  . ILE D 1 96  ? -8.019  -4.848  -51.777 1.00 11.16 ? 98  ILE D CA  1 
ATOM   6167 C C   . ILE D 1 96  ? -6.983  -5.955  -51.658 1.00 11.16 ? 98  ILE D C   1 
ATOM   6168 O O   . ILE D 1 96  ? -5.779  -5.705  -51.805 1.00 11.09 ? 98  ILE D O   1 
ATOM   6169 C CB  . ILE D 1 96  ? -8.001  -4.219  -53.181 1.00 13.06 ? 98  ILE D CB  1 
ATOM   6170 C CG1 . ILE D 1 96  ? -8.961  -3.028  -53.282 1.00 11.50 ? 98  ILE D CG1 1 
ATOM   6171 C CG2 . ILE D 1 96  ? -8.431  -5.228  -54.214 1.00 10.11 ? 98  ILE D CG2 1 
ATOM   6172 C CD1 . ILE D 1 96  ? -8.775  -2.262  -54.616 1.00 10.90 ? 98  ILE D CD1 1 
ATOM   6173 N N   . PHE D 1 97  ? -7.446  -7.176  -51.375 1.00 11.72 ? 99  PHE D N   1 
ATOM   6174 C CA  . PHE D 1 97  ? -6.574  -8.327  -51.174 1.00 13.07 ? 99  PHE D CA  1 
ATOM   6175 C C   . PHE D 1 97  ? -6.562  -9.151  -52.447 1.00 12.51 ? 99  PHE D C   1 
ATOM   6176 O O   . PHE D 1 97  ? -7.605  -9.684  -52.838 1.00 13.65 ? 99  PHE D O   1 
ATOM   6177 C CB  . PHE D 1 97  ? -7.087  -9.209  -50.032 1.00 12.21 ? 99  PHE D CB  1 
ATOM   6178 C CG  . PHE D 1 97  ? -6.960  -8.595  -48.668 1.00 15.53 ? 99  PHE D CG  1 
ATOM   6179 C CD1 . PHE D 1 97  ? -5.761  -8.654  -47.975 1.00 13.67 ? 99  PHE D CD1 1 
ATOM   6180 C CD2 . PHE D 1 97  ? -8.039  -7.936  -48.091 1.00 14.16 ? 99  PHE D CD2 1 
ATOM   6181 C CE1 . PHE D 1 97  ? -5.649  -8.108  -46.693 1.00 15.53 ? 99  PHE D CE1 1 
ATOM   6182 C CE2 . PHE D 1 97  ? -7.939  -7.386  -46.810 1.00 17.43 ? 99  PHE D CE2 1 
ATOM   6183 C CZ  . PHE D 1 97  ? -6.741  -7.465  -46.115 1.00 17.23 ? 99  PHE D CZ  1 
ATOM   6184 N N   . PHE D 1 98  ? -5.389  -9.288  -53.070 1.00 12.25 ? 100 PHE D N   1 
ATOM   6185 C CA  . PHE D 1 98  ? -5.243  -10.148 -54.233 1.00 13.83 ? 100 PHE D CA  1 
ATOM   6186 C C   . PHE D 1 98  ? -4.824  -11.515 -53.726 1.00 13.55 ? 100 PHE D C   1 
ATOM   6187 O O   . PHE D 1 98  ? -3.723  -11.670 -53.204 1.00 15.50 ? 100 PHE D O   1 
ATOM   6188 C CB  . PHE D 1 98  ? -4.224  -9.575  -55.212 1.00 11.66 ? 100 PHE D CB  1 
ATOM   6189 C CG  . PHE D 1 98  ? -4.697  -8.299  -55.849 1.00 11.91 ? 100 PHE D CG  1 
ATOM   6190 C CD1 . PHE D 1 98  ? -5.529  -8.331  -56.959 1.00 11.98 ? 100 PHE D CD1 1 
ATOM   6191 C CD2 . PHE D 1 98  ? -4.380  -7.071  -55.275 1.00 10.95 ? 100 PHE D CD2 1 
ATOM   6192 C CE1 . PHE D 1 98  ? -5.995  -7.138  -57.537 1.00 10.64 ? 100 PHE D CE1 1 
ATOM   6193 C CE2 . PHE D 1 98  ? -4.833  -5.885  -55.835 1.00 11.10 ? 100 PHE D CE2 1 
ATOM   6194 C CZ  . PHE D 1 98  ? -5.654  -5.917  -56.963 1.00 11.31 ? 100 PHE D CZ  1 
ATOM   6195 N N   . LYS D 1 99  ? -5.705  -12.497 -53.892 1.00 15.30 ? 101 LYS D N   1 
ATOM   6196 C CA  . LYS D 1 99  ? -5.505  -13.814 -53.309 1.00 15.33 ? 101 LYS D CA  1 
ATOM   6197 C C   . LYS D 1 99  ? -4.157  -14.391 -53.725 1.00 15.75 ? 101 LYS D C   1 
ATOM   6198 O O   . LYS D 1 99  ? -3.770  -14.315 -54.892 1.00 17.23 ? 101 LYS D O   1 
ATOM   6199 C CB  . LYS D 1 99  ? -6.646  -14.733 -53.734 1.00 22.26 ? 101 LYS D CB  1 
ATOM   6200 C CG  . LYS D 1 99  ? -7.032  -15.797 -52.707 1.00 27.80 ? 101 LYS D CG  1 
ATOM   6201 C CD  . LYS D 1 99  ? -7.167  -17.152 -53.361 1.00 30.81 ? 101 LYS D CD  1 
ATOM   6202 C CE  . LYS D 1 99  ? -8.016  -18.093 -52.497 1.00 35.84 ? 101 LYS D CE  1 
ATOM   6203 N NZ  . LYS D 1 99  ? -7.455  -18.245 -51.128 1.00 33.73 ? 101 LYS D NZ  1 
ATOM   6204 N N   . ASP D 1 100 ? -3.434  -14.929 -52.739 1.00 15.36 ? 102 ASP D N   1 
ATOM   6205 C CA  . ASP D 1 100 ? -2.089  -15.479 -52.900 1.00 19.12 ? 102 ASP D CA  1 
ATOM   6206 C C   . ASP D 1 100 ? -1.105  -14.447 -53.444 1.00 18.57 ? 102 ASP D C   1 
ATOM   6207 O O   . ASP D 1 100 ? -0.096  -14.808 -54.053 1.00 18.31 ? 102 ASP D O   1 
ATOM   6208 C CB  . ASP D 1 100 ? -2.088  -16.729 -53.784 1.00 18.59 ? 102 ASP D CB  1 
ATOM   6209 C CG  . ASP D 1 100 ? -2.936  -17.858 -53.201 1.00 23.57 ? 102 ASP D CG  1 
ATOM   6210 O OD1 . ASP D 1 100 ? -2.858  -18.098 -51.988 1.00 28.33 ? 102 ASP D OD1 1 
ATOM   6211 O OD2 . ASP D 1 100 ? -3.630  -18.551 -53.965 1.00 29.69 ? 102 ASP D OD2 1 
ATOM   6212 N N   . ASP D 1 101 ? -1.369  -13.165 -53.212 1.00 16.12 ? 103 ASP D N   1 
ATOM   6213 C CA  . ASP D 1 101 ? -0.453  -12.109 -53.625 1.00 15.16 ? 103 ASP D CA  1 
ATOM   6214 C C   . ASP D 1 101 ? -0.617  -10.945 -52.647 1.00 15.19 ? 103 ASP D C   1 
ATOM   6215 O O   . ASP D 1 101 ? -1.133  -11.121 -51.535 1.00 15.43 ? 103 ASP D O   1 
ATOM   6216 C CB  . ASP D 1 101 ? -0.715  -11.710 -55.088 1.00 16.31 ? 103 ASP D CB  1 
ATOM   6217 C CG  . ASP D 1 101 ? 0.544   -11.294 -55.819 1.00 16.76 ? 103 ASP D CG  1 
ATOM   6218 O OD1 . ASP D 1 101 ? 1.473   -10.780 -55.169 1.00 16.54 ? 103 ASP D OD1 1 
ATOM   6219 O OD2 . ASP D 1 101 ? 0.593   -11.451 -57.055 1.00 16.22 ? 103 ASP D OD2 1 
ATOM   6220 N N   . GLY D 1 102 ? -0.179  -9.755  -53.056 1.00 14.71 ? 104 GLY D N   1 
ATOM   6221 C CA  . GLY D 1 102 ? -0.170  -8.594  -52.187 1.00 13.48 ? 104 GLY D CA  1 
ATOM   6222 C C   . GLY D 1 102 ? -1.519  -7.900  -52.097 1.00 13.99 ? 104 GLY D C   1 
ATOM   6223 O O   . GLY D 1 102 ? -2.556  -8.399  -52.540 1.00 13.25 ? 104 GLY D O   1 
ATOM   6224 N N   . ASN D 1 103 ? -1.497  -6.709  -51.496 1.00 12.89 ? 105 ASN D N   1 
ATOM   6225 C CA  . ASN D 1 103 ? -2.718  -5.937  -51.305 1.00 13.26 ? 105 ASN D CA  1 
ATOM   6226 C C   . ASN D 1 103 ? -2.524  -4.478  -51.705 1.00 12.45 ? 105 ASN D C   1 
ATOM   6227 O O   . ASN D 1 103 ? -1.418  -3.938  -51.655 1.00 12.59 ? 105 ASN D O   1 
ATOM   6228 C CB  . ASN D 1 103 ? -3.205  -6.023  -49.837 1.00 14.24 ? 105 ASN D CB  1 
ATOM   6229 C CG  . ASN D 1 103 ? -2.192  -5.477  -48.853 1.00 15.49 ? 105 ASN D CG  1 
ATOM   6230 O OD1 . ASN D 1 103 ? -2.140  -4.269  -48.593 1.00 14.97 ? 105 ASN D OD1 1 
ATOM   6231 N ND2 . ASN D 1 103 ? -1.410  -6.379  -48.249 1.00 16.46 ? 105 ASN D ND2 1 
ATOM   6232 N N   . TYR D 1 104 ? -3.618  -3.856  -52.139 1.00 10.97 ? 106 TYR D N   1 
ATOM   6233 C CA  . TYR D 1 104 ? -3.682  -2.415  -52.330 1.00 10.98 ? 106 TYR D CA  1 
ATOM   6234 C C   . TYR D 1 104 ? -4.386  -1.806  -51.133 1.00 12.94 ? 106 TYR D C   1 
ATOM   6235 O O   . TYR D 1 104 ? -5.356  -2.379  -50.621 1.00 13.30 ? 106 TYR D O   1 
ATOM   6236 C CB  . TYR D 1 104 ? -4.469  -1.994  -53.581 1.00 8.99  ? 106 TYR D CB  1 
ATOM   6237 C CG  . TYR D 1 104 ? -3.920  -2.373  -54.935 1.00 11.30 ? 106 TYR D CG  1 
ATOM   6238 C CD1 . TYR D 1 104 ? -2.604  -2.759  -55.102 1.00 10.51 ? 106 TYR D CD1 1 
ATOM   6239 C CD2 . TYR D 1 104 ? -4.735  -2.291  -56.066 1.00 10.84 ? 106 TYR D CD2 1 
ATOM   6240 C CE1 . TYR D 1 104 ? -2.110  -3.106  -56.370 1.00 13.08 ? 106 TYR D CE1 1 
ATOM   6241 C CE2 . TYR D 1 104 ? -4.261  -2.647  -57.328 1.00 11.93 ? 106 TYR D CE2 1 
ATOM   6242 C CZ  . TYR D 1 104 ? -2.950  -3.048  -57.472 1.00 14.19 ? 106 TYR D CZ  1 
ATOM   6243 O OH  . TYR D 1 104 ? -2.472  -3.386  -58.722 1.00 10.71 ? 106 TYR D OH  1 
ATOM   6244 N N   . LYS D 1 105 ? -3.899  -0.641  -50.707 1.00 12.06 ? 107 LYS D N   1 
ATOM   6245 C CA  . LYS D 1 105 ? -4.633  0.250   -49.826 1.00 13.54 ? 107 LYS D CA  1 
ATOM   6246 C C   . LYS D 1 105 ? -4.796  1.565   -50.568 1.00 10.98 ? 107 LYS D C   1 
ATOM   6247 O O   . LYS D 1 105 ? -3.820  2.077   -51.129 1.00 11.69 ? 107 LYS D O   1 
ATOM   6248 C CB  . LYS D 1 105 ? -3.871  0.463   -48.514 1.00 14.98 ? 107 LYS D CB  1 
ATOM   6249 C CG  . LYS D 1 105 ? -3.828  -0.792  -47.679 1.00 18.60 ? 107 LYS D CG  1 
ATOM   6250 C CD  . LYS D 1 105 ? -4.987  -0.825  -46.759 1.00 27.63 ? 107 LYS D CD  1 
ATOM   6251 C CE  . LYS D 1 105 ? -4.489  -0.894  -45.337 1.00 29.42 ? 107 LYS D CE  1 
ATOM   6252 N NZ  . LYS D 1 105 ? -5.594  -0.822  -44.363 1.00 27.02 ? 107 LYS D NZ  1 
ATOM   6253 N N   . THR D 1 106 ? -6.021  2.093   -50.607 1.00 10.34 ? 108 THR D N   1 
ATOM   6254 C CA  . THR D 1 106 ? -6.308  3.295   -51.375 1.00 10.74 ? 108 THR D CA  1 
ATOM   6255 C C   . THR D 1 106 ? -7.050  4.298   -50.511 1.00 11.62 ? 108 THR D C   1 
ATOM   6256 O O   . THR D 1 106 ? -7.880  3.920   -49.684 1.00 15.34 ? 108 THR D O   1 
ATOM   6257 C CB  . THR D 1 106 ? -7.153  2.982   -52.642 1.00 12.42 ? 108 THR D CB  1 
ATOM   6258 O OG1 . THR D 1 106 ? -8.447  2.498   -52.253 1.00 12.48 ? 108 THR D OG1 1 
ATOM   6259 C CG2 . THR D 1 106 ? -6.460  1.912   -53.503 1.00 11.13 ? 108 THR D CG2 1 
ATOM   6260 N N   . ARG D 1 107 ? -6.752  5.576   -50.712 1.00 12.64 ? 109 ARG D N   1 
ATOM   6261 C CA  . ARG D 1 107 ? -7.522  6.655   -50.106 1.00 11.94 ? 109 ARG D CA  1 
ATOM   6262 C C   . ARG D 1 107 ? -7.823  7.668   -51.188 1.00 13.26 ? 109 ARG D C   1 
ATOM   6263 O O   . ARG D 1 107 ? -6.903  8.154   -51.844 1.00 13.98 ? 109 ARG D O   1 
ATOM   6264 C CB  . ARG D 1 107 ? -6.755  7.371   -48.986 1.00 13.41 ? 109 ARG D CB  1 
ATOM   6265 C CG  . ARG D 1 107 ? -7.651  8.296   -48.148 1.00 16.17 ? 109 ARG D CG  1 
ATOM   6266 C CD  . ARG D 1 107 ? -6.841  9.116   -47.109 1.00 23.05 ? 109 ARG D CD  1 
ATOM   6267 N NE  . ARG D 1 107 ? -7.664  10.089  -46.392 1.00 20.77 ? 109 ARG D NE  1 
ATOM   6268 C CZ  . ARG D 1 107 ? -8.051  11.280  -46.836 1.00 26.99 ? 109 ARG D CZ  1 
ATOM   6269 N NH1 . ARG D 1 107 ? -7.677  11.740  -48.019 1.00 23.88 ? 109 ARG D NH1 1 
ATOM   6270 N NH2 . ARG D 1 107 ? -8.836  12.032  -46.066 1.00 28.76 ? 109 ARG D NH2 1 
ATOM   6271 N N   . ALA D 1 108 ? -9.087  8.013   -51.354 1.00 11.64 ? 110 ALA D N   1 
ATOM   6272 C CA  . ALA D 1 108 ? -9.464  8.927   -52.417 1.00 11.99 ? 110 ALA D CA  1 
ATOM   6273 C C   . ALA D 1 108 ? -10.383 9.990   -51.850 1.00 13.56 ? 110 ALA D C   1 
ATOM   6274 O O   . ALA D 1 108 ? -11.131 9.734   -50.911 1.00 14.33 ? 110 ALA D O   1 
ATOM   6275 C CB  . ALA D 1 108 ? -10.179 8.203   -53.570 1.00 13.01 ? 110 ALA D CB  1 
ATOM   6276 N N   . GLU D 1 109 ? -10.323 11.179  -52.439 1.00 13.56 ? 111 GLU D N   1 
ATOM   6277 C CA  . GLU D 1 109 ? -11.330 12.205  -52.227 1.00 14.90 ? 111 GLU D CA  1 
ATOM   6278 C C   . GLU D 1 109 ? -12.049 12.438  -53.549 1.00 13.68 ? 111 GLU D C   1 
ATOM   6279 O O   . GLU D 1 109 ? -11.408 12.633  -54.585 1.00 13.14 ? 111 GLU D O   1 
ATOM   6280 C CB  . GLU D 1 109 ? -10.698 13.491  -51.713 1.00 14.91 ? 111 GLU D CB  1 
ATOM   6281 C CG  . GLU D 1 109 ? -10.179 13.290  -50.308 1.00 20.79 ? 111 GLU D CG  1 
ATOM   6282 C CD  . GLU D 1 109 ? -9.769  14.568  -49.626 1.00 23.13 ? 111 GLU D CD  1 
ATOM   6283 O OE1 . GLU D 1 109 ? -9.966  15.646  -50.210 1.00 22.07 ? 111 GLU D OE1 1 
ATOM   6284 O OE2 . GLU D 1 109 ? -9.225  14.474  -48.509 1.00 29.65 ? 111 GLU D OE2 1 
ATOM   6285 N N   . VAL D 1 110 ? -13.371 12.369  -53.512 1.00 12.65 ? 112 VAL D N   1 
ATOM   6286 C CA  . VAL D 1 110 ? -14.210 12.607  -54.678 1.00 12.92 ? 112 VAL D CA  1 
ATOM   6287 C C   . VAL D 1 110 ? -14.990 13.880  -54.399 1.00 15.42 ? 112 VAL D C   1 
ATOM   6288 O O   . VAL D 1 110 ? -15.745 13.932  -53.425 1.00 14.58 ? 112 VAL D O   1 
ATOM   6289 C CB  . VAL D 1 110 ? -15.159 11.431  -54.936 1.00 13.87 ? 112 VAL D CB  1 
ATOM   6290 C CG1 . VAL D 1 110 ? -15.921 11.652  -56.246 1.00 13.08 ? 112 VAL D CG1 1 
ATOM   6291 C CG2 . VAL D 1 110 ? -14.374 10.106  -54.993 1.00 16.85 ? 112 VAL D CG2 1 
ATOM   6292 N N   . LYS D 1 111 ? -14.824 14.900  -55.240 1.00 14.05 ? 113 LYS D N   1 
ATOM   6293 C CA  . LYS D 1 111 ? -15.457 16.185  -54.959 1.00 14.49 ? 113 LYS D CA  1 
ATOM   6294 C C   . LYS D 1 111 ? -15.499 17.026  -56.218 1.00 12.98 ? 113 LYS D C   1 
ATOM   6295 O O   . LYS D 1 111 ? -14.820 16.743  -57.206 1.00 13.25 ? 113 LYS D O   1 
ATOM   6296 C CB  . LYS D 1 111 ? -14.719 16.942  -53.857 1.00 13.85 ? 113 LYS D CB  1 
ATOM   6297 C CG  . LYS D 1 111 ? -13.326 17.405  -54.286 1.00 15.03 ? 113 LYS D CG  1 
ATOM   6298 C CD  . LYS D 1 111 ? -12.638 17.952  -53.037 1.00 22.28 ? 113 LYS D CD  1 
ATOM   6299 C CE  . LYS D 1 111 ? -11.473 17.096  -52.603 1.00 22.15 ? 113 LYS D CE  1 
ATOM   6300 N NZ  . LYS D 1 111 ? -10.637 17.788  -51.576 1.00 27.73 ? 113 LYS D NZ  1 
ATOM   6301 N N   . PHE D 1 112 ? -16.303 18.082  -56.168 1.00 13.19 ? 114 PHE D N   1 
ATOM   6302 C CA  . PHE D 1 112 ? -16.377 19.001  -57.297 1.00 15.08 ? 114 PHE D CA  1 
ATOM   6303 C C   . PHE D 1 112 ? -15.274 20.039  -57.187 1.00 14.13 ? 114 PHE D C   1 
ATOM   6304 O O   . PHE D 1 112 ? -14.988 20.551  -56.101 1.00 14.31 ? 114 PHE D O   1 
ATOM   6305 C CB  . PHE D 1 112 ? -17.744 19.683  -57.371 1.00 15.33 ? 114 PHE D CB  1 
ATOM   6306 C CG  . PHE D 1 112 ? -18.743 18.933  -58.214 1.00 14.45 ? 114 PHE D CG  1 
ATOM   6307 C CD1 . PHE D 1 112 ? -18.815 19.138  -59.581 1.00 17.79 ? 114 PHE D CD1 1 
ATOM   6308 C CD2 . PHE D 1 112 ? -19.588 17.996  -57.634 1.00 14.11 ? 114 PHE D CD2 1 
ATOM   6309 C CE1 . PHE D 1 112 ? -19.732 18.428  -60.353 1.00 18.66 ? 114 PHE D CE1 1 
ATOM   6310 C CE2 . PHE D 1 112 ? -20.495 17.286  -58.396 1.00 13.57 ? 114 PHE D CE2 1 
ATOM   6311 C CZ  . PHE D 1 112 ? -20.572 17.498  -59.748 1.00 14.68 ? 114 PHE D CZ  1 
ATOM   6312 N N   . GLU D 1 113 ? -14.633 20.312  -58.317 1.00 13.20 ? 115 GLU D N   1 
ATOM   6313 C CA  . GLU D 1 113 ? -13.677 21.397  -58.438 1.00 19.90 ? 115 GLU D CA  1 
ATOM   6314 C C   . GLU D 1 113 ? -14.158 22.225  -59.619 1.00 16.93 ? 115 GLU D C   1 
ATOM   6315 O O   . GLU D 1 113 ? -14.044 21.788  -60.766 1.00 19.37 ? 115 GLU D O   1 
ATOM   6316 C CB  . GLU D 1 113 ? -12.267 20.858  -58.656 1.00 15.35 ? 115 GLU D CB  1 
ATOM   6317 C CG  . GLU D 1 113 ? -11.704 20.299  -57.381 1.00 18.61 ? 115 GLU D CG  1 
ATOM   6318 C CD  . GLU D 1 113 ? -10.328 19.732  -57.535 1.00 18.53 ? 115 GLU D CD  1 
ATOM   6319 O OE1 . GLU D 1 113 ? -9.625  20.086  -58.519 1.00 20.52 ? 115 GLU D OE1 1 
ATOM   6320 O OE2 . GLU D 1 113 ? -9.930  18.965  -56.643 1.00 27.83 ? 115 GLU D OE2 1 
ATOM   6321 N N   . GLY D 1 114 ? -14.743 23.384  -59.346 1.00 18.12 ? 116 GLY D N   1 
ATOM   6322 C CA  . GLY D 1 114 ? -15.441 24.081  -60.406 1.00 21.94 ? 116 GLY D CA  1 
ATOM   6323 C C   . GLY D 1 114 ? -16.622 23.227  -60.818 1.00 19.79 ? 116 GLY D C   1 
ATOM   6324 O O   . GLY D 1 114 ? -17.332 22.674  -59.977 1.00 19.97 ? 116 GLY D O   1 
ATOM   6325 N N   . ASP D 1 115 ? -16.815 23.064  -62.118 1.00 19.29 ? 117 ASP D N   1 
ATOM   6326 C CA  . ASP D 1 115 ? -17.889 22.221  -62.619 1.00 19.04 ? 117 ASP D CA  1 
ATOM   6327 C C   . ASP D 1 115 ? -17.435 20.791  -62.881 1.00 19.58 ? 117 ASP D C   1 
ATOM   6328 O O   . ASP D 1 115 ? -18.178 20.029  -63.503 1.00 18.25 ? 117 ASP D O   1 
ATOM   6329 C CB  . ASP D 1 115 ? -18.471 22.822  -63.900 1.00 27.00 ? 117 ASP D CB  1 
ATOM   6330 C CG  . ASP D 1 115 ? -19.383 24.005  -63.627 1.00 31.47 ? 117 ASP D CG  1 
ATOM   6331 O OD1 . ASP D 1 115 ? -20.021 24.043  -62.549 1.00 31.68 ? 117 ASP D OD1 1 
ATOM   6332 O OD2 . ASP D 1 115 ? -19.453 24.895  -64.498 1.00 35.23 ? 117 ASP D OD2 1 
ATOM   6333 N N   . THR D 1 116 ? -16.243 20.410  -62.421 1.00 16.56 ? 118 THR D N   1 
ATOM   6334 C CA  . THR D 1 116 ? -15.668 19.099  -62.713 1.00 16.23 ? 118 THR D CA  1 
ATOM   6335 C C   . THR D 1 116 ? -15.732 18.193  -61.492 1.00 14.59 ? 118 THR D C   1 
ATOM   6336 O O   . THR D 1 116 ? -15.365 18.604  -60.385 1.00 13.52 ? 118 THR D O   1 
ATOM   6337 C CB  . THR D 1 116 ? -14.221 19.243  -63.193 1.00 14.56 ? 118 THR D CB  1 
ATOM   6338 O OG1 . THR D 1 116 ? -14.209 20.024  -64.397 1.00 17.43 ? 118 THR D OG1 1 
ATOM   6339 C CG2 . THR D 1 116 ? -13.582 17.875  -63.479 1.00 12.77 ? 118 THR D CG2 1 
ATOM   6340 N N   . LEU D 1 117 ? -16.202 16.963  -61.693 1.00 15.39 ? 119 LEU D N   1 
ATOM   6341 C CA  . LEU D 1 117 ? -16.130 15.947  -60.652 1.00 13.66 ? 119 LEU D CA  1 
ATOM   6342 C C   . LEU D 1 117 ? -14.734 15.335  -60.665 1.00 11.61 ? 119 LEU D C   1 
ATOM   6343 O O   . LEU D 1 117 ? -14.341 14.710  -61.655 1.00 11.86 ? 119 LEU D O   1 
ATOM   6344 C CB  . LEU D 1 117 ? -17.206 14.883  -60.875 1.00 13.55 ? 119 LEU D CB  1 
ATOM   6345 C CG  . LEU D 1 117 ? -17.424 13.873  -59.750 1.00 12.26 ? 119 LEU D CG  1 
ATOM   6346 C CD1 . LEU D 1 117 ? -16.355 12.763  -59.775 1.00 13.01 ? 119 LEU D CD1 1 
ATOM   6347 C CD2 . LEU D 1 117 ? -17.489 14.574  -58.377 1.00 12.38 ? 119 LEU D CD2 1 
ATOM   6348 N N   . VAL D 1 118 ? -14.002 15.478  -59.555 1.00 12.44 ? 120 VAL D N   1 
ATOM   6349 C CA  . VAL D 1 118 ? -12.612 15.039  -59.440 1.00 11.62 ? 120 VAL D CA  1 
ATOM   6350 C C   . VAL D 1 118 ? -12.501 13.884  -58.449 1.00 11.38 ? 120 VAL D C   1 
ATOM   6351 O O   . VAL D 1 118 ? -12.956 13.994  -57.307 1.00 12.97 ? 120 VAL D O   1 
ATOM   6352 C CB  . VAL D 1 118 ? -11.700 16.198  -58.998 1.00 13.13 ? 120 VAL D CB  1 
ATOM   6353 C CG1 . VAL D 1 118 ? -10.250 15.733  -58.976 1.00 11.64 ? 120 VAL D CG1 1 
ATOM   6354 C CG2 . VAL D 1 118 ? -11.869 17.369  -59.963 1.00 13.30 ? 120 VAL D CG2 1 
ATOM   6355 N N   . ASN D 1 119 ? -11.850 12.802  -58.880 1.00 10.60 ? 121 ASN D N   1 
ATOM   6356 C CA  . ASN D 1 119 ? -11.485 11.662  -58.041 1.00 9.84  ? 121 ASN D CA  1 
ATOM   6357 C C   . ASN D 1 119 ? -9.966  11.663  -57.919 1.00 12.38 ? 121 ASN D C   1 
ATOM   6358 O O   . ASN D 1 119 ? -9.264  11.382  -58.899 1.00 10.76 ? 121 ASN D O   1 
ATOM   6359 C CB  . ASN D 1 119 ? -11.990 10.344  -58.657 1.00 8.79  ? 121 ASN D CB  1 
ATOM   6360 C CG  . ASN D 1 119 ? -11.602 9.134   -57.844 1.00 11.21 ? 121 ASN D CG  1 
ATOM   6361 O OD1 . ASN D 1 119 ? -11.267 9.265   -56.675 1.00 12.98 ? 121 ASN D OD1 1 
ATOM   6362 N ND2 . ASN D 1 119 ? -11.650 7.929   -58.460 1.00 9.87  ? 121 ASN D ND2 1 
ATOM   6363 N N   . ARG D 1 120 ? -9.452  11.999  -56.731 1.00 11.32 ? 122 ARG D N   1 
ATOM   6364 C CA  . ARG D 1 120 ? -8.011  12.075  -56.506 1.00 13.23 ? 122 ARG D CA  1 
ATOM   6365 C C   . ARG D 1 120 ? -7.612  10.989  -55.525 1.00 14.67 ? 122 ARG D C   1 
ATOM   6366 O O   . ARG D 1 120 ? -8.138  10.939  -54.409 1.00 14.91 ? 122 ARG D O   1 
ATOM   6367 C CB  . ARG D 1 120 ? -7.591  13.447  -55.978 1.00 17.86 ? 122 ARG D CB  1 
ATOM   6368 C CG  . ARG D 1 120 ? -6.081  13.689  -56.064 1.00 21.65 ? 122 ARG D CG  1 
ATOM   6369 C CD  . ARG D 1 120 ? -5.751  15.111  -55.618 1.00 24.70 ? 122 ARG D CD  1 
ATOM   6370 N NE  . ARG D 1 120 ? -6.272  16.097  -56.560 1.00 22.54 ? 122 ARG D NE  1 
ATOM   6371 C CZ  . ARG D 1 120 ? -5.689  16.394  -57.715 1.00 20.16 ? 122 ARG D CZ  1 
ATOM   6372 N NH1 . ARG D 1 120 ? -4.560  15.818  -58.087 1.00 19.40 ? 122 ARG D NH1 1 
ATOM   6373 N NH2 . ARG D 1 120 ? -6.238  17.314  -58.504 1.00 22.03 ? 122 ARG D NH2 1 
ATOM   6374 N N   . ILE D 1 121 ? -6.665  10.142  -55.930 1.00 11.36 ? 123 ILE D N   1 
ATOM   6375 C CA  . ILE D 1 121 ? -6.410  8.874   -55.255 1.00 11.29 ? 123 ILE D CA  1 
ATOM   6376 C C   . ILE D 1 121 ? -4.948  8.785   -54.857 1.00 13.13 ? 123 ILE D C   1 
ATOM   6377 O O   . ILE D 1 121 ? -4.071  9.211   -55.610 1.00 11.66 ? 123 ILE D O   1 
ATOM   6378 C CB  . ILE D 1 121 ? -6.747  7.676   -56.169 1.00 13.41 ? 123 ILE D CB  1 
ATOM   6379 C CG1 . ILE D 1 121 ? -8.156  7.801   -56.724 1.00 14.19 ? 123 ILE D CG1 1 
ATOM   6380 C CG2 . ILE D 1 121 ? -6.566  6.373   -55.387 1.00 11.82 ? 123 ILE D CG2 1 
ATOM   6381 C CD1 . ILE D 1 121 ? -8.194  7.487   -58.221 1.00 13.36 ? 123 ILE D CD1 1 
ATOM   6382 N N   . GLU D 1 122 ? -4.694  8.193   -53.689 1.00 14.30 ? 124 GLU D N   1 
ATOM   6383 C CA  . GLU D 1 122 ? -3.383  7.721   -53.276 1.00 14.56 ? 124 GLU D CA  1 
ATOM   6384 C C   . GLU D 1 122 ? -3.477  6.204   -53.140 1.00 12.70 ? 124 GLU D C   1 
ATOM   6385 O O   . GLU D 1 122 ? -4.362  5.709   -52.444 1.00 14.45 ? 124 GLU D O   1 
ATOM   6386 C CB  . GLU D 1 122 ? -3.017  8.351   -51.933 1.00 16.20 ? 124 GLU D CB  1 
ATOM   6387 C CG  . GLU D 1 122 ? -2.463  9.729   -52.028 1.00 22.99 ? 124 GLU D CG  1 
ATOM   6388 C CD  . GLU D 1 122 ? -2.370  10.393  -50.659 1.00 36.26 ? 124 GLU D CD  1 
ATOM   6389 O OE1 . GLU D 1 122 ? -1.564  11.334  -50.528 1.00 42.79 ? 124 GLU D OE1 1 
ATOM   6390 O OE2 . GLU D 1 122 ? -3.113  9.984   -49.728 1.00 43.30 ? 124 GLU D OE2 1 
ATOM   6391 N N   . LEU D 1 123 ? -2.606  5.468   -53.828 1.00 10.70 ? 125 LEU D N   1 
ATOM   6392 C CA  . LEU D 1 123 ? -2.627  4.008   -53.788 1.00 13.75 ? 125 LEU D CA  1 
ATOM   6393 C C   . LEU D 1 123 ? -1.283  3.496   -53.303 1.00 11.99 ? 125 LEU D C   1 
ATOM   6394 O O   . LEU D 1 123 ? -0.241  3.898   -53.829 1.00 11.54 ? 125 LEU D O   1 
ATOM   6395 C CB  . LEU D 1 123 ? -2.952  3.417   -55.169 1.00 9.64  ? 125 LEU D CB  1 
ATOM   6396 C CG  . LEU D 1 123 ? -3.032  1.881   -55.299 1.00 11.58 ? 125 LEU D CG  1 
ATOM   6397 C CD1 . LEU D 1 123 ? -4.032  1.510   -56.386 1.00 11.72 ? 125 LEU D CD1 1 
ATOM   6398 C CD2 . LEU D 1 123 ? -1.654  1.248   -55.591 1.00 10.66 ? 125 LEU D CD2 1 
ATOM   6399 N N   . LYS D 1 124 ? -1.301  2.587   -52.324 1.00 12.46 ? 126 LYS D N   1 
ATOM   6400 C CA  . LYS D 1 124 ? -0.083  1.918   -51.866 1.00 14.32 ? 126 LYS D CA  1 
ATOM   6401 C C   . LYS D 1 124 ? -0.280  0.414   -51.955 1.00 13.63 ? 126 LYS D C   1 
ATOM   6402 O O   . LYS D 1 124 ? -1.216  -0.122  -51.356 1.00 13.82 ? 126 LYS D O   1 
ATOM   6403 C CB  . LYS D 1 124 ? 0.285   2.311   -50.427 1.00 19.28 ? 126 LYS D CB  1 
ATOM   6404 C CG  . LYS D 1 124 ? 1.482   1.512   -49.868 1.00 25.68 ? 126 LYS D CG  1 
ATOM   6405 C CD  . LYS D 1 124 ? 2.822   2.087   -50.338 1.00 31.00 ? 126 LYS D CD  1 
ATOM   6406 C CE  . LYS D 1 124 ? 4.014   1.139   -50.047 1.00 27.72 ? 126 LYS D CE  1 
ATOM   6407 N NZ  . LYS D 1 124 ? 4.406   0.319   -51.291 1.00 20.17 ? 126 LYS D NZ  1 
ATOM   6408 N N   . GLY D 1 125 ? 0.597   -0.259  -52.687 1.00 12.62 ? 127 GLY D N   1 
ATOM   6409 C CA  . GLY D 1 125 ? 0.577   -1.716  -52.801 1.00 14.77 ? 127 GLY D CA  1 
ATOM   6410 C C   . GLY D 1 125 ? 1.814   -2.281  -52.126 1.00 15.39 ? 127 GLY D C   1 
ATOM   6411 O O   . GLY D 1 125 ? 2.912   -1.757  -52.304 1.00 15.45 ? 127 GLY D O   1 
ATOM   6412 N N   . ILE D 1 126 ? 1.633   -3.363  -51.360 1.00 14.52 ? 128 ILE D N   1 
ATOM   6413 C CA  . ILE D 1 126 ? 2.721   -3.966  -50.595 1.00 15.52 ? 128 ILE D CA  1 
ATOM   6414 C C   . ILE D 1 126 ? 2.621   -5.479  -50.703 1.00 17.80 ? 128 ILE D C   1 
ATOM   6415 O O   . ILE D 1 126 ? 1.547   -6.034  -50.941 1.00 13.81 ? 128 ILE D O   1 
ATOM   6416 C CB  . ILE D 1 126 ? 2.692   -3.568  -49.103 1.00 17.35 ? 128 ILE D CB  1 
ATOM   6417 C CG1 . ILE D 1 126 ? 1.459   -4.171  -48.417 1.00 19.83 ? 128 ILE D CG1 1 
ATOM   6418 C CG2 . ILE D 1 126 ? 2.656   -2.054  -48.952 1.00 22.66 ? 128 ILE D CG2 1 
ATOM   6419 C CD1 . ILE D 1 126 ? 1.524   -4.164  -46.902 1.00 25.93 ? 128 ILE D CD1 1 
ATOM   6420 N N   . ASP D 1 127 ? 3.768   -6.149  -50.517 1.00 15.49 ? 129 ASP D N   1 
ATOM   6421 C CA  . ASP D 1 127 ? 3.822   -7.599  -50.350 1.00 18.38 ? 129 ASP D CA  1 
ATOM   6422 C C   . ASP D 1 127 ? 3.476   -8.365  -51.624 1.00 17.91 ? 129 ASP D C   1 
ATOM   6423 O O   . ASP D 1 127 ? 3.036   -9.512  -51.558 1.00 16.16 ? 129 ASP D O   1 
ATOM   6424 C CB  . ASP D 1 127 ? 2.908   -8.011  -49.183 1.00 18.24 ? 129 ASP D CB  1 
ATOM   6425 C CG  . ASP D 1 127 ? 3.356   -7.395  -47.851 1.00 19.26 ? 129 ASP D CG  1 
ATOM   6426 O OD1 . ASP D 1 127 ? 2.751   -7.700  -46.810 1.00 28.36 ? 129 ASP D OD1 1 
ATOM   6427 O OD2 . ASP D 1 127 ? 4.403   -6.720  -47.820 1.00 19.27 ? 129 ASP D OD2 1 
ATOM   6428 N N   . PHE D 1 128 ? 3.682   -7.769  -52.795 1.00 14.84 ? 130 PHE D N   1 
ATOM   6429 C CA  . PHE D 1 128 ? 3.395   -8.470  -54.036 1.00 14.82 ? 130 PHE D CA  1 
ATOM   6430 C C   . PHE D 1 128 ? 4.577   -9.342  -54.444 1.00 16.13 ? 130 PHE D C   1 
ATOM   6431 O O   . PHE D 1 128 ? 5.733   -9.066  -54.101 1.00 16.54 ? 130 PHE D O   1 
ATOM   6432 C CB  . PHE D 1 128 ? 3.069   -7.468  -55.155 1.00 13.56 ? 130 PHE D CB  1 
ATOM   6433 C CG  . PHE D 1 128 ? 1.667   -6.904  -55.062 1.00 13.17 ? 130 PHE D CG  1 
ATOM   6434 C CD1 . PHE D 1 128 ? 0.601   -7.541  -55.678 1.00 13.92 ? 130 PHE D CD1 1 
ATOM   6435 C CD2 . PHE D 1 128 ? 1.416   -5.759  -54.320 1.00 13.44 ? 130 PHE D CD2 1 
ATOM   6436 C CE1 . PHE D 1 128 ? -0.683  -7.041  -55.562 1.00 13.00 ? 130 PHE D CE1 1 
ATOM   6437 C CE2 . PHE D 1 128 ? 0.126   -5.234  -54.209 1.00 12.14 ? 130 PHE D CE2 1 
ATOM   6438 C CZ  . PHE D 1 128 ? -0.925  -5.878  -54.827 1.00 12.24 ? 130 PHE D CZ  1 
ATOM   6439 N N   . LYS D 1 129 ? 4.277   -10.393 -55.201 1.00 16.62 ? 131 LYS D N   1 
ATOM   6440 C CA  . LYS D 1 129 ? 5.302   -11.254 -55.771 1.00 18.32 ? 131 LYS D CA  1 
ATOM   6441 C C   . LYS D 1 129 ? 5.764   -10.657 -57.091 1.00 18.24 ? 131 LYS D C   1 
ATOM   6442 O O   . LYS D 1 129 ? 4.937   -10.308 -57.937 1.00 19.07 ? 131 LYS D O   1 
ATOM   6443 C CB  . LYS D 1 129 ? 4.758   -12.665 -55.986 1.00 21.62 ? 131 LYS D CB  1 
ATOM   6444 C CG  . LYS D 1 129 ? 4.275   -13.372 -54.720 1.00 21.43 ? 131 LYS D CG  1 
ATOM   6445 C CD  . LYS D 1 129 ? 3.524   -14.659 -55.081 1.00 24.60 ? 131 LYS D CD  1 
ATOM   6446 C CE  . LYS D 1 129 ? 3.065   -15.443 -53.841 1.00 29.56 ? 131 LYS D CE  1 
ATOM   6447 N N   . GLU D 1 130 ? 7.082   -10.543 -57.281 1.00 19.02 ? 132 GLU D N   1 
ATOM   6448 C CA  . GLU D 1 130 ? 7.546   -9.890  -58.505 1.00 23.08 ? 132 GLU D CA  1 
ATOM   6449 C C   . GLU D 1 130 ? 7.143   -10.653 -59.762 1.00 24.89 ? 132 GLU D C   1 
ATOM   6450 O O   . GLU D 1 130 ? 6.964   -10.037 -60.816 1.00 26.93 ? 132 GLU D O   1 
ATOM   6451 C CB  . GLU D 1 130 ? 9.059   -9.674  -58.485 1.00 27.54 ? 132 GLU D CB  1 
ATOM   6452 C CG  . GLU D 1 130 ? 9.493   -8.386  -57.806 1.00 32.26 ? 132 GLU D CG  1 
ATOM   6453 C CD  . GLU D 1 130 ? 9.063   -7.131  -58.581 1.00 34.70 ? 132 GLU D CD  1 
ATOM   6454 O OE1 . GLU D 1 130 ? 8.807   -7.223  -59.813 1.00 33.29 ? 132 GLU D OE1 1 
ATOM   6455 O OE2 . GLU D 1 130 ? 9.036   -6.040  -57.964 1.00 28.76 ? 132 GLU D OE2 1 
ATOM   6456 N N   . ASP D 1 131 ? 6.978   -11.974 -59.681 1.00 24.63 ? 133 ASP D N   1 
ATOM   6457 C CA  . ASP D 1 131 ? 6.514   -12.759 -60.821 1.00 27.93 ? 133 ASP D CA  1 
ATOM   6458 C C   . ASP D 1 131 ? 5.117   -13.337 -60.587 1.00 23.82 ? 133 ASP D C   1 
ATOM   6459 O O   . ASP D 1 131 ? 4.741   -14.344 -61.190 1.00 25.02 ? 133 ASP D O   1 
ATOM   6460 C CB  . ASP D 1 131 ? 7.518   -13.864 -61.162 1.00 29.69 ? 133 ASP D CB  1 
ATOM   6461 C CG  . ASP D 1 131 ? 7.203   -14.565 -62.495 1.00 41.21 ? 133 ASP D CG  1 
ATOM   6462 O OD1 . ASP D 1 131 ? 7.266   -13.912 -63.565 1.00 45.87 ? 133 ASP D OD1 1 
ATOM   6463 O OD2 . ASP D 1 131 ? 6.885   -15.779 -62.467 1.00 47.05 ? 133 ASP D OD2 1 
ATOM   6464 N N   . GLY D 1 132 ? 4.330   -12.706 -59.724 1.00 23.01 ? 134 GLY D N   1 
ATOM   6465 C CA  . GLY D 1 132 ? 2.936   -13.068 -59.579 1.00 19.44 ? 134 GLY D CA  1 
ATOM   6466 C C   . GLY D 1 132 ? 2.101   -12.489 -60.711 1.00 18.58 ? 134 GLY D C   1 
ATOM   6467 O O   . GLY D 1 132 ? 2.604   -11.872 -61.649 1.00 17.30 ? 134 GLY D O   1 
ATOM   6468 N N   . ASN D 1 133 ? 0.786   -12.672 -60.595 1.00 17.65 ? 135 ASN D N   1 
ATOM   6469 C CA  . ASN D 1 133 ? -0.110  -12.262 -61.670 1.00 17.07 ? 135 ASN D CA  1 
ATOM   6470 C C   . ASN D 1 133 ? -0.165  -10.749 -61.832 1.00 16.20 ? 135 ASN D C   1 
ATOM   6471 O O   . ASN D 1 133 ? -0.493  -10.262 -62.918 1.00 13.68 ? 135 ASN D O   1 
ATOM   6472 C CB  . ASN D 1 133 ? -1.510  -12.817 -61.411 1.00 17.89 ? 135 ASN D CB  1 
ATOM   6473 C CG  . ASN D 1 133 ? -1.564  -14.319 -61.581 1.00 17.43 ? 135 ASN D CG  1 
ATOM   6474 O OD1 . ASN D 1 133 ? -0.872  -14.866 -62.430 1.00 19.16 ? 135 ASN D OD1 1 
ATOM   6475 N ND2 . ASN D 1 133 ? -2.369  -14.997 -60.761 1.00 15.93 ? 135 ASN D ND2 1 
ATOM   6476 N N   . ILE D 1 134 ? 0.169   -9.993  -60.792 1.00 14.74 ? 136 ILE D N   1 
ATOM   6477 C CA  . ILE D 1 134 ? -0.040  -8.549  -60.837 1.00 14.33 ? 136 ILE D CA  1 
ATOM   6478 C C   . ILE D 1 134 ? 1.232   -7.898  -61.365 1.00 13.60 ? 136 ILE D C   1 
ATOM   6479 O O   . ILE D 1 134 ? 1.255   -7.371  -62.484 1.00 15.00 ? 136 ILE D O   1 
ATOM   6480 C CB  . ILE D 1 134 ? -0.447  -8.005  -59.455 1.00 13.37 ? 136 ILE D CB  1 
ATOM   6481 C CG1 . ILE D 1 134 ? -1.913  -8.353  -59.163 1.00 15.84 ? 136 ILE D CG1 1 
ATOM   6482 C CG2 . ILE D 1 134 ? -0.382  -6.481  -59.427 1.00 13.65 ? 136 ILE D CG2 1 
ATOM   6483 C CD1 . ILE D 1 134 ? -2.143  -9.738  -58.664 1.00 18.04 ? 136 ILE D CD1 1 
ATOM   6484 N N   . LEU D 1 135 ? 2.308   -7.952  -60.577 1.00 14.54 ? 137 LEU D N   1 
ATOM   6485 C CA  . LEU D 1 135 ? 3.571   -7.375  -61.024 1.00 15.53 ? 137 LEU D CA  1 
ATOM   6486 C C   . LEU D 1 135 ? 4.119   -8.096  -62.254 1.00 14.96 ? 137 LEU D C   1 
ATOM   6487 O O   . LEU D 1 135 ? 4.912   -7.515  -62.999 1.00 14.99 ? 137 LEU D O   1 
ATOM   6488 C CB  . LEU D 1 135 ? 4.574   -7.416  -59.868 1.00 16.66 ? 137 LEU D CB  1 
ATOM   6489 C CG  . LEU D 1 135 ? 4.351   -6.393  -58.741 1.00 17.81 ? 137 LEU D CG  1 
ATOM   6490 C CD1 . LEU D 1 135 ? 5.517   -6.382  -57.788 1.00 18.81 ? 137 LEU D CD1 1 
ATOM   6491 C CD2 . LEU D 1 135 ? 4.111   -4.980  -59.291 1.00 18.38 ? 137 LEU D CD2 1 
ATOM   6492 N N   . GLY D 1 136 ? 3.705   -9.335  -62.495 1.00 16.06 ? 138 GLY D N   1 
ATOM   6493 C CA  . GLY D 1 136 ? 4.095   -10.024 -63.708 1.00 16.49 ? 138 GLY D CA  1 
ATOM   6494 C C   . GLY D 1 136 ? 3.226   -9.765  -64.922 1.00 19.17 ? 138 GLY D C   1 
ATOM   6495 O O   . GLY D 1 136 ? 3.519   -10.295 -65.999 1.00 19.36 ? 138 GLY D O   1 
ATOM   6496 N N   . HIS D 1 137 ? 2.173   -8.960  -64.795 1.00 15.21 ? 139 HIS D N   1 
ATOM   6497 C CA  . HIS D 1 137 ? 1.256   -8.666  -65.901 1.00 14.79 ? 139 HIS D CA  1 
ATOM   6498 C C   . HIS D 1 137 ? 0.737   -9.947  -66.568 1.00 16.48 ? 139 HIS D C   1 
ATOM   6499 O O   . HIS D 1 137 ? 0.908   -10.169 -67.772 1.00 16.00 ? 139 HIS D O   1 
ATOM   6500 C CB  . HIS D 1 137 ? 1.926   -7.753  -66.937 1.00 19.17 ? 139 HIS D CB  1 
ATOM   6501 C CG  . HIS D 1 137 ? 2.241   -6.382  -66.419 1.00 19.13 ? 139 HIS D CG  1 
ATOM   6502 N ND1 . HIS D 1 137 ? 3.467   -6.047  -65.878 1.00 20.66 ? 139 HIS D ND1 1 
ATOM   6503 C CD2 . HIS D 1 137 ? 1.498   -5.251  -66.392 1.00 14.64 ? 139 HIS D CD2 1 
ATOM   6504 C CE1 . HIS D 1 137 ? 3.451   -4.777  -65.511 1.00 16.03 ? 139 HIS D CE1 1 
ATOM   6505 N NE2 . HIS D 1 137 ? 2.273   -4.270  -65.822 1.00 18.48 ? 139 HIS D NE2 1 
ATOM   6506 N N   . LYS D 1 138 ? 0.049   -10.774 -65.781 1.00 13.34 ? 140 LYS D N   1 
ATOM   6507 C CA  . LYS D 1 138 ? -0.486  -12.034 -66.289 1.00 15.68 ? 140 LYS D CA  1 
ATOM   6508 C C   . LYS D 1 138 ? -2.010  -12.065 -66.309 1.00 16.52 ? 140 LYS D C   1 
ATOM   6509 O O   . LYS D 1 138 ? -2.609  -13.149 -66.333 1.00 17.19 ? 140 LYS D O   1 
ATOM   6510 C CB  . LYS D 1 138 ? 0.051   -13.207 -65.469 1.00 16.85 ? 140 LYS D CB  1 
ATOM   6511 C CG  . LYS D 1 138 ? 1.569   -13.312 -65.470 1.00 18.64 ? 140 LYS D CG  1 
ATOM   6512 C CD  . LYS D 1 138 ? 2.024   -14.447 -64.551 1.00 22.76 ? 140 LYS D CD  1 
ATOM   6513 C CE  . LYS D 1 138 ? 3.529   -14.462 -64.388 1.00 25.65 ? 140 LYS D CE  1 
ATOM   6514 N NZ  . LYS D 1 138 ? 3.960   -15.570 -63.494 1.00 25.98 ? 140 LYS D NZ  1 
ATOM   6515 N N   . LEU D 1 139 ? -2.655  -10.902 -66.306 1.00 12.26 ? 141 LEU D N   1 
ATOM   6516 C CA  . LEU D 1 139 ? -4.107  -10.829 -66.295 1.00 13.93 ? 141 LEU D CA  1 
ATOM   6517 C C   . LEU D 1 139 ? -4.596  -10.384 -67.661 1.00 15.66 ? 141 LEU D C   1 
ATOM   6518 O O   . LEU D 1 139 ? -3.977  -9.526  -68.292 1.00 14.75 ? 141 LEU D O   1 
ATOM   6519 C CB  . LEU D 1 139 ? -4.589  -9.846  -65.230 1.00 11.86 ? 141 LEU D CB  1 
ATOM   6520 C CG  . LEU D 1 139 ? -4.217  -10.146 -63.787 1.00 13.21 ? 141 LEU D CG  1 
ATOM   6521 C CD1 . LEU D 1 139 ? -4.929  -9.138  -62.888 1.00 12.35 ? 141 LEU D CD1 1 
ATOM   6522 C CD2 . LEU D 1 139 ? -4.646  -11.568 -63.403 1.00 12.93 ? 141 LEU D CD2 1 
ATOM   6523 N N   . GLU D 1 140 ? -5.691  -10.988 -68.116 1.00 13.66 ? 142 GLU D N   1 
ATOM   6524 C CA  . GLU D 1 140 ? -6.303  -10.604 -69.377 1.00 16.72 ? 142 GLU D CA  1 
ATOM   6525 C C   . GLU D 1 140 ? -6.802  -9.170  -69.317 1.00 17.37 ? 142 GLU D C   1 
ATOM   6526 O O   . GLU D 1 140 ? -7.198  -8.670  -68.260 1.00 15.93 ? 142 GLU D O   1 
ATOM   6527 C CB  . GLU D 1 140 ? -7.478  -11.524 -69.701 1.00 17.92 ? 142 GLU D CB  1 
ATOM   6528 C CG  . GLU D 1 140 ? -7.067  -12.932 -70.013 1.00 18.24 ? 142 GLU D CG  1 
ATOM   6529 C CD  . GLU D 1 140 ? -8.246  -13.833 -70.291 1.00 21.16 ? 142 GLU D CD  1 
ATOM   6530 O OE1 . GLU D 1 140 ? -9.396  -13.341 -70.319 1.00 16.28 ? 142 GLU D OE1 1 
ATOM   6531 O OE2 . GLU D 1 140 ? -8.002  -15.027 -70.563 1.00 19.67 ? 142 GLU D OE2 1 
ATOM   6532 N N   . TYR D 1 141 ? -6.829  -8.520  -70.481 1.00 14.80 ? 143 TYR D N   1 
ATOM   6533 C CA  . TYR D 1 141 ? -7.303  -7.140  -70.567 1.00 14.49 ? 143 TYR D CA  1 
ATOM   6534 C C   . TYR D 1 141 ? -8.801  -7.150  -70.845 1.00 17.75 ? 143 TYR D C   1 
ATOM   6535 O O   . TYR D 1 141 ? -9.265  -6.925  -71.968 1.00 15.24 ? 143 TYR D O   1 
ATOM   6536 C CB  . TYR D 1 141 ? -6.558  -6.370  -71.644 1.00 15.63 ? 143 TYR D CB  1 
ATOM   6537 C CG  . TYR D 1 141 ? -6.925  -4.895  -71.691 1.00 14.95 ? 143 TYR D CG  1 
ATOM   6538 C CD1 . TYR D 1 141 ? -6.520  -4.035  -70.679 1.00 13.56 ? 143 TYR D CD1 1 
ATOM   6539 C CD2 . TYR D 1 141 ? -7.641  -4.365  -72.756 1.00 14.05 ? 143 TYR D CD2 1 
ATOM   6540 C CE1 . TYR D 1 141 ? -6.837  -2.699  -70.714 1.00 12.01 ? 143 TYR D CE1 1 
ATOM   6541 C CE2 . TYR D 1 141 ? -7.953  -3.029  -72.816 1.00 11.58 ? 143 TYR D CE2 1 
ATOM   6542 C CZ  . TYR D 1 141 ? -7.534  -2.188  -71.793 1.00 12.84 ? 143 TYR D CZ  1 
ATOM   6543 O OH  . TYR D 1 141 ? -7.849  -0.847  -71.823 1.00 13.00 ? 143 TYR D OH  1 
ATOM   6544 N N   . ASN D 1 142 ? -9.567  -7.404  -69.791 1.00 13.43 ? 144 ASN D N   1 
ATOM   6545 C CA  . ASN D 1 142 ? -11.022 -7.399  -69.867 1.00 16.49 ? 144 ASN D CA  1 
ATOM   6546 C C   . ASN D 1 142 ? -11.521 -7.300  -68.432 1.00 15.41 ? 144 ASN D C   1 
ATOM   6547 O O   . ASN D 1 142 ? -10.736 -7.029  -67.518 1.00 16.55 ? 144 ASN D O   1 
ATOM   6548 C CB  . ASN D 1 142 ? -11.542 -8.620  -70.644 1.00 17.74 ? 144 ASN D CB  1 
ATOM   6549 C CG  . ASN D 1 142 ? -11.075 -9.949  -70.066 1.00 19.26 ? 144 ASN D CG  1 
ATOM   6550 O OD1 . ASN D 1 142 ? -10.871 -10.090 -68.864 1.00 19.23 ? 144 ASN D OD1 1 
ATOM   6551 N ND2 . ASN D 1 142 ? -10.830 -10.909 -70.945 1.00 18.64 ? 144 ASN D ND2 1 
ATOM   6552 N N   . TYR D 1 143 ? -12.821 -7.484  -68.220 1.00 12.19 ? 145 TYR D N   1 
ATOM   6553 C CA  . TYR D 1 143 ? -13.341 -7.219  -66.883 1.00 16.25 ? 145 TYR D CA  1 
ATOM   6554 C C   . TYR D 1 143 ? -14.578 -8.050  -66.603 1.00 18.62 ? 145 TYR D C   1 
ATOM   6555 O O   . TYR D 1 143 ? -15.477 -8.140  -67.447 1.00 20.72 ? 145 TYR D O   1 
ATOM   6556 C CB  . TYR D 1 143 ? -13.686 -5.734  -66.681 1.00 15.32 ? 145 TYR D CB  1 
ATOM   6557 C CG  . TYR D 1 143 ? -13.530 -5.298  -65.235 1.00 12.17 ? 145 TYR D CG  1 
ATOM   6558 C CD1 . TYR D 1 143 ? -12.269 -5.110  -64.686 1.00 13.05 ? 145 TYR D CD1 1 
ATOM   6559 C CD2 . TYR D 1 143 ? -14.636 -5.145  -64.398 1.00 13.36 ? 145 TYR D CD2 1 
ATOM   6560 C CE1 . TYR D 1 143 ? -12.108 -4.721  -63.358 1.00 10.27 ? 145 TYR D CE1 1 
ATOM   6561 C CE2 . TYR D 1 143 ? -14.481 -4.758  -63.052 1.00 12.94 ? 145 TYR D CE2 1 
ATOM   6562 C CZ  . TYR D 1 143 ? -13.219 -4.565  -62.551 1.00 11.07 ? 145 TYR D CZ  1 
ATOM   6563 O OH  . TYR D 1 143 ? -13.032 -4.189  -61.235 1.00 12.93 ? 145 TYR D OH  1 
ATOM   6564 N N   . ASN D 1 144 ? -14.627 -8.626  -65.391 1.00 16.02 ? 146 ASN D N   1 
ATOM   6565 C CA  . ASN D 1 144 ? -15.826 -9.265  -64.849 1.00 16.99 ? 146 ASN D CA  1 
ATOM   6566 C C   . ASN D 1 144 ? -16.321 -8.365  -63.718 1.00 14.92 ? 146 ASN D C   1 
ATOM   6567 O O   . ASN D 1 144 ? -15.698 -8.308  -62.655 1.00 14.66 ? 146 ASN D O   1 
ATOM   6568 C CB  . ASN D 1 144 ? -15.534 -10.662 -64.300 1.00 19.19 ? 146 ASN D CB  1 
ATOM   6569 C CG  . ASN D 1 144 ? -14.868 -11.572 -65.303 1.00 24.70 ? 146 ASN D CG  1 
ATOM   6570 O OD1 . ASN D 1 144 ? -15.309 -11.704 -66.445 1.00 23.40 ? 146 ASN D OD1 1 
ATOM   6571 N ND2 . ASN D 1 144 ? -13.816 -12.254 -64.855 1.00 19.90 ? 146 ASN D ND2 1 
ATOM   6572 N N   . ASP D 1 145 ? -17.423 -7.659  -63.940 1.00 13.38 ? 147 ASP D N   1 
ATOM   6573 C CA  . ASP D 1 145 ? -17.964 -6.796  -62.897 1.00 13.27 ? 147 ASP D CA  1 
ATOM   6574 C C   . ASP D 1 145 ? -18.632 -7.619  -61.801 1.00 12.89 ? 147 ASP D C   1 
ATOM   6575 O O   . ASP D 1 145 ? -18.879 -8.816  -61.946 1.00 14.80 ? 147 ASP D O   1 
ATOM   6576 C CB  . ASP D 1 145 ? -18.975 -5.835  -63.496 1.00 13.89 ? 147 ASP D CB  1 
ATOM   6577 C CG  . ASP D 1 145 ? -18.334 -4.872  -64.427 1.00 14.37 ? 147 ASP D CG  1 
ATOM   6578 O OD1 . ASP D 1 145 ? -17.720 -3.921  -63.913 1.00 11.52 ? 147 ASP D OD1 1 
ATOM   6579 O OD2 . ASP D 1 145 ? -18.391 -5.120  -65.658 1.00 14.32 ? 147 ASP D OD2 1 
ATOM   6580 N N   . HIS D 1 146 ? -18.923 -6.954  -60.684 1.00 11.62 ? 148 HIS D N   1 
ATOM   6581 C CA  . HIS D 1 146 ? -19.669 -7.575  -59.607 1.00 13.95 ? 148 HIS D CA  1 
ATOM   6582 C C   . HIS D 1 146 ? -20.483 -6.509  -58.889 1.00 16.48 ? 148 HIS D C   1 
ATOM   6583 O O   . HIS D 1 146 ? -20.066 -5.348  -58.780 1.00 15.03 ? 148 HIS D O   1 
ATOM   6584 C CB  . HIS D 1 146 ? -18.734 -8.307  -58.632 1.00 17.38 ? 148 HIS D CB  1 
ATOM   6585 C CG  . HIS D 1 146 ? -19.434 -9.322  -57.785 1.00 19.13 ? 148 HIS D CG  1 
ATOM   6586 N ND1 . HIS D 1 146 ? -20.005 -9.013  -56.569 1.00 19.04 ? 148 HIS D ND1 1 
ATOM   6587 C CD2 . HIS D 1 146 ? -19.721 -10.624 -58.016 1.00 24.70 ? 148 HIS D CD2 1 
ATOM   6588 C CE1 . HIS D 1 146 ? -20.565 -10.099 -56.060 1.00 20.17 ? 148 HIS D CE1 1 
ATOM   6589 N NE2 . HIS D 1 146 ? -20.419 -11.086 -56.924 1.00 25.98 ? 148 HIS D NE2 1 
ATOM   6590 N N   . GLN D 1 147 ? -21.665 -6.915  -58.437 1.00 14.13 ? 149 GLN D N   1 
ATOM   6591 C CA  . GLN D 1 147 ? -22.538 -6.046  -57.671 1.00 15.69 ? 149 GLN D CA  1 
ATOM   6592 C C   . GLN D 1 147 ? -21.839 -5.631  -56.386 1.00 12.78 ? 149 GLN D C   1 
ATOM   6593 O O   . GLN D 1 147 ? -20.983 -6.349  -55.855 1.00 15.49 ? 149 GLN D O   1 
ATOM   6594 C CB  . GLN D 1 147 ? -23.835 -6.774  -57.327 1.00 21.42 ? 149 GLN D CB  1 
ATOM   6595 C CG  . GLN D 1 147 ? -23.564 -8.113  -56.645 1.00 20.76 ? 149 GLN D CG  1 
ATOM   6596 C CD  . GLN D 1 147 ? -24.391 -9.259  -57.175 1.00 30.80 ? 149 GLN D CD  1 
ATOM   6597 O OE1 . GLN D 1 147 ? -25.456 -9.058  -57.745 1.00 38.55 ? 149 GLN D OE1 1 
ATOM   6598 N NE2 . GLN D 1 147 ? -23.914 -10.482 -56.960 1.00 35.91 ? 149 GLN D NE2 1 
ATOM   6599 N N   . VAL D 1 148 ? -22.228 -4.471  -55.871 1.00 13.68 ? 150 VAL D N   1 
ATOM   6600 C CA  . VAL D 1 148 ? -21.714 -3.981  -54.600 1.00 13.92 ? 150 VAL D CA  1 
ATOM   6601 C C   . VAL D 1 148 ? -22.910 -3.701  -53.698 1.00 16.23 ? 150 VAL D C   1 
ATOM   6602 O O   . VAL D 1 148 ? -23.797 -2.923  -54.067 1.00 14.23 ? 150 VAL D O   1 
ATOM   6603 C CB  . VAL D 1 148 ? -20.859 -2.718  -54.771 1.00 15.50 ? 150 VAL D CB  1 
ATOM   6604 C CG1 . VAL D 1 148 ? -20.409 -2.206  -53.393 1.00 16.22 ? 150 VAL D CG1 1 
ATOM   6605 C CG2 . VAL D 1 148 ? -19.654 -3.006  -55.673 1.00 14.37 ? 150 VAL D CG2 1 
ATOM   6606 N N   . TYR D 1 149 ? -22.924 -4.317  -52.518 1.00 15.22 ? 151 TYR D N   1 
ATOM   6607 C CA  . TYR D 1 149 ? -23.991 -4.106  -51.548 1.00 17.89 ? 151 TYR D CA  1 
ATOM   6608 C C   . TYR D 1 149 ? -23.577 -2.957  -50.638 1.00 17.90 ? 151 TYR D C   1 
ATOM   6609 O O   . TYR D 1 149 ? -22.669 -3.102  -49.813 1.00 18.95 ? 151 TYR D O   1 
ATOM   6610 C CB  . TYR D 1 149 ? -24.262 -5.379  -50.758 1.00 16.58 ? 151 TYR D CB  1 
ATOM   6611 C CG  . TYR D 1 149 ? -25.437 -5.291  -49.815 1.00 24.78 ? 151 TYR D CG  1 
ATOM   6612 C CD1 . TYR D 1 149 ? -26.739 -5.141  -50.295 1.00 28.17 ? 151 TYR D CD1 1 
ATOM   6613 C CD2 . TYR D 1 149 ? -25.253 -5.395  -48.446 1.00 26.97 ? 151 TYR D CD2 1 
ATOM   6614 C CE1 . TYR D 1 149 ? -27.822 -5.073  -49.420 1.00 31.12 ? 151 TYR D CE1 1 
ATOM   6615 C CE2 . TYR D 1 149 ? -26.319 -5.328  -47.571 1.00 29.80 ? 151 TYR D CE2 1 
ATOM   6616 C CZ  . TYR D 1 149 ? -27.594 -5.173  -48.059 1.00 32.34 ? 151 TYR D CZ  1 
ATOM   6617 O OH  . TYR D 1 149 ? -28.634 -5.120  -47.162 1.00 37.71 ? 151 TYR D OH  1 
ATOM   6618 N N   . ILE D 1 150 ? -24.233 -1.819  -50.803 1.00 17.34 ? 152 ILE D N   1 
ATOM   6619 C CA  . ILE D 1 150 ? -23.925 -0.608  -50.054 1.00 18.34 ? 152 ILE D CA  1 
ATOM   6620 C C   . ILE D 1 150 ? -24.699 -0.633  -48.739 1.00 21.50 ? 152 ILE D C   1 
ATOM   6621 O O   . ILE D 1 150 ? -25.934 -0.696  -48.739 1.00 21.81 ? 152 ILE D O   1 
ATOM   6622 C CB  . ILE D 1 150 ? -24.267 0.640   -50.880 1.00 17.77 ? 152 ILE D CB  1 
ATOM   6623 C CG1 . ILE D 1 150 ? -23.533 0.536   -52.224 1.00 18.58 ? 152 ILE D CG1 1 
ATOM   6624 C CG2 . ILE D 1 150 ? -23.966 1.930   -50.105 1.00 19.73 ? 152 ILE D CG2 1 
ATOM   6625 C CD1 . ILE D 1 150 ? -22.144 1.074   -52.189 1.00 17.45 ? 152 ILE D CD1 1 
ATOM   6626 N N   . MET D 1 151 ? -23.973 -0.560  -47.625 1.00 20.76 ? 153 MET D N   1 
ATOM   6627 C CA  . MET D 1 151 ? -24.546 -0.596  -46.281 1.00 20.36 ? 153 MET D CA  1 
ATOM   6628 C C   . MET D 1 151 ? -24.313 0.726   -45.564 1.00 20.39 ? 153 MET D C   1 
ATOM   6629 O O   . MET D 1 151 ? -23.174 1.208   -45.477 1.00 18.54 ? 153 MET D O   1 
ATOM   6630 C CB  . MET D 1 151 ? -23.953 -1.739  -45.454 1.00 20.28 ? 153 MET D CB  1 
ATOM   6631 C CG  . MET D 1 151 ? -24.016 -3.085  -46.130 1.00 29.40 ? 153 MET D CG  1 
ATOM   6632 S SD  . MET D 1 151 ? -23.553 -4.449  -45.029 1.00 33.53 ? 153 MET D SD  1 
ATOM   6633 C CE  . MET D 1 151 ? -24.725 -4.209  -43.688 1.00 30.27 ? 153 MET D CE  1 
ATOM   6634 N N   . ALA D 1 152 ? -25.392 1.298   -45.034 1.00 19.75 ? 154 ALA D N   1 
ATOM   6635 C CA  . ALA D 1 152 ? -25.279 2.531   -44.274 1.00 25.26 ? 154 ALA D CA  1 
ATOM   6636 C C   . ALA D 1 152 ? -24.445 2.304   -43.021 1.00 22.32 ? 154 ALA D C   1 
ATOM   6637 O O   . ALA D 1 152 ? -24.555 1.266   -42.358 1.00 23.60 ? 154 ALA D O   1 
ATOM   6638 C CB  . ALA D 1 152 ? -26.666 3.051   -43.893 1.00 28.00 ? 154 ALA D CB  1 
ATOM   6639 N N   . ASP D 1 153 ? -23.602 3.282   -42.712 1.00 24.19 ? 155 ASP D N   1 
ATOM   6640 C CA  . ASP D 1 153 ? -22.840 3.364   -41.467 1.00 27.52 ? 155 ASP D CA  1 
ATOM   6641 C C   . ASP D 1 153 ? -23.277 4.640   -40.748 1.00 29.40 ? 155 ASP D C   1 
ATOM   6642 O O   . ASP D 1 153 ? -22.681 5.705   -40.932 1.00 23.88 ? 155 ASP D O   1 
ATOM   6643 C CB  . ASP D 1 153 ? -21.356 3.389   -41.729 1.00 29.97 ? 155 ASP D CB  1 
ATOM   6644 C CG  . ASP D 1 153 ? -20.544 3.422   -40.449 1.00 39.38 ? 155 ASP D CG  1 
ATOM   6645 O OD1 . ASP D 1 153 ? -21.115 3.638   -39.356 1.00 38.38 ? 155 ASP D OD1 1 
ATOM   6646 O OD2 . ASP D 1 153 ? -19.315 3.282   -40.545 1.00 42.71 ? 155 ASP D OD2 1 
ATOM   6647 N N   . LYS D 1 154 ? -24.295 4.526   -39.902 1.00 33.66 ? 156 LYS D N   1 
ATOM   6648 C CA  . LYS D 1 154 ? -24.855 5.724   -39.284 1.00 34.11 ? 156 LYS D CA  1 
ATOM   6649 C C   . LYS D 1 154 ? -23.840 6.420   -38.384 1.00 33.06 ? 156 LYS D C   1 
ATOM   6650 O O   . LYS D 1 154 ? -23.841 7.653   -38.299 1.00 31.36 ? 156 LYS D O   1 
ATOM   6651 C CB  . LYS D 1 154 ? -26.136 5.385   -38.507 1.00 36.94 ? 156 LYS D CB  1 
ATOM   6652 C CG  . LYS D 1 154 ? -27.280 4.725   -39.321 1.00 39.68 ? 156 LYS D CG  1 
ATOM   6653 C CD  . LYS D 1 154 ? -26.992 3.275   -39.743 1.00 43.55 ? 156 LYS D CD  1 
ATOM   6654 C CE  . LYS D 1 154 ? -26.647 2.409   -38.531 1.00 47.48 ? 156 LYS D CE  1 
ATOM   6655 N NZ  . LYS D 1 154 ? -25.845 1.206   -38.912 1.00 41.18 ? 156 LYS D NZ  1 
ATOM   6656 N N   . GLN D 1 155 ? -22.935 5.661   -37.754 1.00 31.91 ? 157 GLN D N   1 
ATOM   6657 C CA  . GLN D 1 155 ? -22.019 6.254   -36.783 1.00 34.67 ? 157 GLN D CA  1 
ATOM   6658 C C   . GLN D 1 155 ? -21.005 7.179   -37.448 1.00 35.53 ? 157 GLN D C   1 
ATOM   6659 O O   . GLN D 1 155 ? -20.576 8.165   -36.838 1.00 35.17 ? 157 GLN D O   1 
ATOM   6660 C CB  . GLN D 1 155 ? -21.277 5.172   -35.993 1.00 39.69 ? 157 GLN D CB  1 
ATOM   6661 C CG  . GLN D 1 155 ? -22.154 4.070   -35.381 1.00 40.46 ? 157 GLN D CG  1 
ATOM   6662 C CD  . GLN D 1 155 ? -22.353 2.882   -36.330 1.00 47.51 ? 157 GLN D CD  1 
ATOM   6663 O OE1 . GLN D 1 155 ? -23.093 2.961   -37.321 1.00 44.16 ? 157 GLN D OE1 1 
ATOM   6664 N NE2 . GLN D 1 155 ? -21.681 1.770   -36.024 1.00 49.32 ? 157 GLN D NE2 1 
ATOM   6665 N N   . LYS D 1 156 ? -20.596 6.883   -38.682 1.00 31.97 ? 158 LYS D N   1 
ATOM   6666 C CA  . LYS D 1 156 ? -19.656 7.731   -39.403 1.00 26.43 ? 158 LYS D CA  1 
ATOM   6667 C C   . LYS D 1 156 ? -20.335 8.576   -40.470 1.00 28.64 ? 158 LYS D C   1 
ATOM   6668 O O   . LYS D 1 156 ? -19.648 9.269   -41.227 1.00 29.35 ? 158 LYS D O   1 
ATOM   6669 C CB  . LYS D 1 156 ? -18.540 6.892   -40.030 1.00 32.24 ? 158 LYS D CB  1 
ATOM   6670 C CG  . LYS D 1 156 ? -18.132 5.677   -39.213 1.00 38.16 ? 158 LYS D CG  1 
ATOM   6671 C CD  . LYS D 1 156 ? -16.605 5.496   -39.187 1.00 45.78 ? 158 LYS D CD  1 
ATOM   6672 C CE  . LYS D 1 156 ? -16.122 4.828   -37.897 1.00 44.66 ? 158 LYS D CE  1 
ATOM   6673 N NZ  . LYS D 1 156 ? -16.139 5.753   -36.723 1.00 46.14 ? 158 LYS D NZ  1 
ATOM   6674 N N   . ASN D 1 157 ? -21.665 8.540   -40.540 1.00 25.18 ? 159 ASN D N   1 
ATOM   6675 C CA  . ASN D 1 157 ? -22.422 9.330   -41.496 1.00 27.71 ? 159 ASN D CA  1 
ATOM   6676 C C   . ASN D 1 157 ? -22.111 8.897   -42.929 1.00 29.30 ? 159 ASN D C   1 
ATOM   6677 O O   . ASN D 1 157 ? -22.179 9.699   -43.861 1.00 26.18 ? 159 ASN D O   1 
ATOM   6678 C CB  . ASN D 1 157 ? -22.128 10.824  -41.310 1.00 30.45 ? 159 ASN D CB  1 
ATOM   6679 C CG  . ASN D 1 157 ? -23.346 11.692  -41.471 1.00 38.60 ? 159 ASN D CG  1 
ATOM   6680 O OD1 . ASN D 1 157 ? -24.453 11.202  -41.709 1.00 39.41 ? 159 ASN D OD1 1 
ATOM   6681 N ND2 . ASN D 1 157 ? -23.148 13.005  -41.355 1.00 35.44 ? 159 ASN D ND2 1 
ATOM   6682 N N   . GLY D 1 158 ? -21.738 7.632   -43.111 1.00 24.80 ? 160 GLY D N   1 
ATOM   6683 C CA  . GLY D 1 158 ? -21.290 7.178   -44.414 1.00 23.38 ? 160 GLY D CA  1 
ATOM   6684 C C   . GLY D 1 158 ? -21.766 5.792   -44.780 1.00 20.44 ? 160 GLY D C   1 
ATOM   6685 O O   . GLY D 1 158 ? -22.794 5.318   -44.289 1.00 19.57 ? 160 GLY D O   1 
ATOM   6686 N N   . ILE D 1 159 ? -21.021 5.122   -45.659 1.00 17.95 ? 161 ILE D N   1 
ATOM   6687 C CA  . ILE D 1 159 ? -21.387 3.788   -46.109 1.00 18.57 ? 161 ILE D CA  1 
ATOM   6688 C C   . ILE D 1 159 ? -20.169 2.879   -46.030 1.00 17.17 ? 161 ILE D C   1 
ATOM   6689 O O   . ILE D 1 159 ? -19.028 3.333   -45.909 1.00 17.54 ? 161 ILE D O   1 
ATOM   6690 C CB  . ILE D 1 159 ? -21.999 3.807   -47.530 1.00 19.37 ? 161 ILE D CB  1 
ATOM   6691 C CG1 . ILE D 1 159 ? -20.992 4.340   -48.558 1.00 17.88 ? 161 ILE D CG1 1 
ATOM   6692 C CG2 . ILE D 1 159 ? -23.305 4.628   -47.546 1.00 20.30 ? 161 ILE D CG2 1 
ATOM   6693 C CD1 . ILE D 1 159 ? -20.305 3.280   -49.351 1.00 19.32 ? 161 ILE D CD1 1 
ATOM   6694 N N   . LYS D 1 160 ? -20.440 1.575   -46.036 1.00 16.88 ? 162 LYS D N   1 
ATOM   6695 C CA  . LYS D 1 160 ? -19.425 0.538   -46.124 1.00 17.55 ? 162 LYS D CA  1 
ATOM   6696 C C   . LYS D 1 160 ? -19.830 -0.510  -47.149 1.00 16.69 ? 162 LYS D C   1 
ATOM   6697 O O   . LYS D 1 160 ? -21.009 -0.660  -47.485 1.00 17.95 ? 162 LYS D O   1 
ATOM   6698 C CB  . LYS D 1 160 ? -19.181 -0.183  -44.791 1.00 20.60 ? 162 LYS D CB  1 
ATOM   6699 C CG  . LYS D 1 160 ? -18.172 0.476   -43.906 1.00 27.01 ? 162 LYS D CG  1 
ATOM   6700 C CD  . LYS D 1 160 ? -18.441 0.210   -42.450 1.00 35.72 ? 162 LYS D CD  1 
ATOM   6701 C CE  . LYS D 1 160 ? -17.708 1.211   -41.608 1.00 33.88 ? 162 LYS D CE  1 
ATOM   6702 N NZ  . LYS D 1 160 ? -16.422 0.674   -41.117 1.00 41.30 ? 162 LYS D NZ  1 
ATOM   6703 N N   . ALA D 1 161 ? -18.836 -1.261  -47.617 1.00 15.11 ? 163 ALA D N   1 
ATOM   6704 C CA  . ALA D 1 161 ? -19.110 -2.368  -48.522 1.00 16.99 ? 163 ALA D CA  1 
ATOM   6705 C C   . ALA D 1 161 ? -17.937 -3.336  -48.511 1.00 15.81 ? 163 ALA D C   1 
ATOM   6706 O O   . ALA D 1 161 ? -16.799 -2.967  -48.212 1.00 15.55 ? 163 ALA D O   1 
ATOM   6707 C CB  . ALA D 1 161 ? -19.375 -1.877  -49.948 1.00 18.03 ? 163 ALA D CB  1 
ATOM   6708 N N   . ASN D 1 162 ? -18.237 -4.585  -48.838 1.00 12.41 ? 164 ASN D N   1 
ATOM   6709 C CA  . ASN D 1 162 ? -17.220 -5.609  -49.042 1.00 15.25 ? 164 ASN D CA  1 
ATOM   6710 C C   . ASN D 1 162 ? -17.690 -6.467  -50.202 1.00 17.23 ? 164 ASN D C   1 
ATOM   6711 O O   . ASN D 1 162 ? -18.831 -6.942  -50.191 1.00 13.98 ? 164 ASN D O   1 
ATOM   6712 C CB  . ASN D 1 162 ? -17.005 -6.449  -47.774 1.00 15.19 ? 164 ASN D CB  1 
ATOM   6713 C CG  . ASN D 1 162 ? -16.312 -7.772  -48.050 1.00 26.78 ? 164 ASN D CG  1 
ATOM   6714 O OD1 . ASN D 1 162 ? -16.848 -8.843  -47.747 1.00 30.50 ? 164 ASN D OD1 1 
ATOM   6715 N ND2 . ASN D 1 162 ? -15.119 -7.710  -48.646 1.00 20.41 ? 164 ASN D ND2 1 
ATOM   6716 N N   . PHE D 1 163 ? -16.842 -6.622  -51.221 1.00 14.64 ? 165 PHE D N   1 
ATOM   6717 C CA  . PHE D 1 163 ? -17.270 -7.347  -52.411 1.00 14.82 ? 165 PHE D CA  1 
ATOM   6718 C C   . PHE D 1 163 ? -16.050 -7.922  -53.108 1.00 12.47 ? 165 PHE D C   1 
ATOM   6719 O O   . PHE D 1 163 ? -14.928 -7.444  -52.935 1.00 14.14 ? 165 PHE D O   1 
ATOM   6720 C CB  . PHE D 1 163 ? -18.041 -6.451  -53.398 1.00 11.64 ? 165 PHE D CB  1 
ATOM   6721 C CG  . PHE D 1 163 ? -17.256 -5.256  -53.892 1.00 13.64 ? 165 PHE D CG  1 
ATOM   6722 C CD1 . PHE D 1 163 ? -17.166 -4.098  -53.138 1.00 13.75 ? 165 PHE D CD1 1 
ATOM   6723 C CD2 . PHE D 1 163 ? -16.644 -5.280  -55.144 1.00 13.69 ? 165 PHE D CD2 1 
ATOM   6724 C CE1 . PHE D 1 163 ? -16.463 -2.984  -53.607 1.00 11.81 ? 165 PHE D CE1 1 
ATOM   6725 C CE2 . PHE D 1 163 ? -15.940 -4.168  -55.617 1.00 13.71 ? 165 PHE D CE2 1 
ATOM   6726 C CZ  . PHE D 1 163 ? -15.852 -3.025  -54.847 1.00 10.70 ? 165 PHE D CZ  1 
ATOM   6727 N N   . LYS D 1 164 ? -16.277 -8.943  -53.921 1.00 13.08 ? 166 LYS D N   1 
ATOM   6728 C CA  . LYS D 1 164 ? -15.195 -9.556  -54.679 1.00 16.10 ? 166 LYS D CA  1 
ATOM   6729 C C   . LYS D 1 164 ? -15.245 -9.218  -56.155 1.00 17.64 ? 166 LYS D C   1 
ATOM   6730 O O   . LYS D 1 164 ? -16.314 -9.210  -56.774 1.00 18.32 ? 166 LYS D O   1 
ATOM   6731 C CB  . LYS D 1 164 ? -15.210 -11.079 -54.536 1.00 22.97 ? 166 LYS D CB  1 
ATOM   6732 C CG  . LYS D 1 164 ? -14.832 -11.523 -53.165 1.00 26.79 ? 166 LYS D CG  1 
ATOM   6733 C CD  . LYS D 1 164 ? -15.245 -12.950 -52.897 1.00 33.17 ? 166 LYS D CD  1 
ATOM   6734 C CE  . LYS D 1 164 ? -15.185 -13.176 -51.406 1.00 39.21 ? 166 LYS D CE  1 
ATOM   6735 N NZ  . LYS D 1 164 ? -15.569 -14.547 -50.971 1.00 49.19 ? 166 LYS D NZ  1 
ATOM   6736 N N   . ILE D 1 165 ? -14.064 -9.003  -56.724 1.00 16.09 ? 167 ILE D N   1 
ATOM   6737 C CA  . ILE D 1 165 ? -13.880 -8.940  -58.163 1.00 14.50 ? 167 ILE D CA  1 
ATOM   6738 C C   . ILE D 1 165 ? -13.020 -10.121 -58.579 1.00 14.41 ? 167 ILE D C   1 
ATOM   6739 O O   . ILE D 1 165 ? -12.055 -10.481 -57.895 1.00 14.39 ? 167 ILE D O   1 
ATOM   6740 C CB  . ILE D 1 165 ? -13.234 -7.611  -58.598 1.00 15.57 ? 167 ILE D CB  1 
ATOM   6741 C CG1 . ILE D 1 165 ? -14.191 -6.465  -58.260 1.00 12.71 ? 167 ILE D CG1 1 
ATOM   6742 C CG2 . ILE D 1 165 ? -12.922 -7.641  -60.076 1.00 12.81 ? 167 ILE D CG2 1 
ATOM   6743 C CD1 . ILE D 1 165 ? -15.395 -6.402  -59.174 1.00 12.59 ? 167 ILE D CD1 1 
ATOM   6744 N N   . ARG D 1 166 ? -13.375 -10.710 -59.705 1.00 12.68 ? 168 ARG D N   1 
ATOM   6745 C CA  . ARG D 1 166 ? -12.761 -11.911 -60.240 1.00 16.00 ? 168 ARG D CA  1 
ATOM   6746 C C   . ARG D 1 166 ? -12.027 -11.466 -61.508 1.00 14.93 ? 168 ARG D C   1 
ATOM   6747 O O   . ARG D 1 166 ? -12.674 -11.025 -62.460 1.00 16.44 ? 168 ARG D O   1 
ATOM   6748 C CB  . ARG D 1 166 ? -13.901 -12.882 -60.543 1.00 24.25 ? 168 ARG D CB  1 
ATOM   6749 C CG  . ARG D 1 166 ? -13.750 -14.308 -60.184 1.00 36.55 ? 168 ARG D CG  1 
ATOM   6750 C CD  . ARG D 1 166 ? -14.048 -14.634 -58.735 1.00 34.64 ? 168 ARG D CD  1 
ATOM   6751 N NE  . ARG D 1 166 ? -15.446 -14.412 -58.386 1.00 43.95 ? 168 ARG D NE  1 
ATOM   6752 C CZ  . ARG D 1 166 ? -16.004 -14.791 -57.241 1.00 44.69 ? 168 ARG D CZ  1 
ATOM   6753 N NH1 . ARG D 1 166 ? -15.329 -15.490 -56.339 1.00 44.41 ? 168 ARG D NH1 1 
ATOM   6754 N NH2 . ARG D 1 166 ? -17.270 -14.461 -56.994 1.00 44.82 ? 168 ARG D NH2 1 
ATOM   6755 N N   . HIS D 1 167 ? -10.690 -11.500 -61.511 1.00 11.93 ? 169 HIS D N   1 
ATOM   6756 C CA  . HIS D 1 167 ? -9.891  -11.074 -62.667 1.00 12.31 ? 169 HIS D CA  1 
ATOM   6757 C C   . HIS D 1 167 ? -9.445  -12.287 -63.482 1.00 13.63 ? 169 HIS D C   1 
ATOM   6758 O O   . HIS D 1 167 ? -8.813  -13.196 -62.947 1.00 16.85 ? 169 HIS D O   1 
ATOM   6759 C CB  . HIS D 1 167 ? -8.625  -10.323 -62.238 1.00 13.54 ? 169 HIS D CB  1 
ATOM   6760 C CG  . HIS D 1 167 ? -8.872  -8.971  -61.642 1.00 11.50 ? 169 HIS D CG  1 
ATOM   6761 N ND1 . HIS D 1 167 ? -9.554  -7.974  -62.301 1.00 11.54 ? 169 HIS D ND1 1 
ATOM   6762 C CD2 . HIS D 1 167 ? -8.525  -8.459  -60.436 1.00 16.73 ? 169 HIS D CD2 1 
ATOM   6763 C CE1 . HIS D 1 167 ? -9.617  -6.901  -61.526 1.00 10.13 ? 169 HIS D CE1 1 
ATOM   6764 N NE2 . HIS D 1 167 ? -8.990  -7.166  -60.394 1.00 14.49 ? 169 HIS D NE2 1 
ATOM   6765 N N   . ASN D 1 168 ? -9.703  -12.265 -64.780 1.00 15.34 ? 170 ASN D N   1 
ATOM   6766 C CA  . ASN D 1 168 ? -9.317  -13.385 -65.634 1.00 16.08 ? 170 ASN D CA  1 
ATOM   6767 C C   . ASN D 1 168 ? -7.795  -13.459 -65.765 1.00 16.00 ? 170 ASN D C   1 
ATOM   6768 O O   . ASN D 1 168 ? -7.143  -12.474 -66.124 1.00 15.76 ? 170 ASN D O   1 
ATOM   6769 C CB  . ASN D 1 168 ? -9.949  -13.211 -67.013 1.00 18.29 ? 170 ASN D CB  1 
ATOM   6770 C CG  . ASN D 1 168 ? -11.440 -13.463 -67.002 1.00 22.45 ? 170 ASN D CG  1 
ATOM   6771 O OD1 . ASN D 1 168 ? -11.944 -14.271 -66.230 1.00 21.06 ? 170 ASN D OD1 1 
ATOM   6772 N ND2 . ASN D 1 168 ? -12.162 -12.708 -67.816 1.00 23.10 ? 170 ASN D ND2 1 
ATOM   6773 N N   . ILE D 1 169 ? -7.230  -14.634 -65.498 1.00 14.97 ? 171 ILE D N   1 
ATOM   6774 C CA  . ILE D 1 169 ? -5.797  -14.882 -65.641 1.00 15.87 ? 171 ILE D CA  1 
ATOM   6775 C C   . ILE D 1 169 ? -5.507  -15.355 -67.061 1.00 16.80 ? 171 ILE D C   1 
ATOM   6776 O O   . ILE D 1 169 ? -6.262  -16.145 -67.634 1.00 16.50 ? 171 ILE D O   1 
ATOM   6777 C CB  . ILE D 1 169 ? -5.314  -15.922 -64.605 1.00 17.67 ? 171 ILE D CB  1 
ATOM   6778 C CG1 . ILE D 1 169 ? -5.670  -15.483 -63.177 1.00 18.31 ? 171 ILE D CG1 1 
ATOM   6779 C CG2 . ILE D 1 169 ? -3.813  -16.156 -64.731 1.00 19.04 ? 171 ILE D CG2 1 
ATOM   6780 N N   . GLU D 1 170 ? -4.403  -14.882 -67.626 1.00 17.27 ? 172 GLU D N   1 
ATOM   6781 C CA  . GLU D 1 170 ? -4.029  -15.295 -68.970 1.00 20.58 ? 172 GLU D CA  1 
ATOM   6782 C C   . GLU D 1 170 ? -3.802  -16.799 -68.968 1.00 19.88 ? 172 GLU D C   1 
ATOM   6783 O O   . GLU D 1 170 ? -3.150  -17.325 -68.064 1.00 18.49 ? 172 GLU D O   1 
ATOM   6784 C CB  . GLU D 1 170 ? -2.760  -14.568 -69.411 1.00 17.91 ? 172 GLU D CB  1 
ATOM   6785 C CG  . GLU D 1 170 ? -3.024  -13.159 -69.945 1.00 21.44 ? 172 GLU D CG  1 
ATOM   6786 C CD  . GLU D 1 170 ? -1.729  -12.406 -70.205 1.00 23.88 ? 172 GLU D CD  1 
ATOM   6787 O OE1 . GLU D 1 170 ? -0.695  -12.827 -69.644 1.00 23.35 ? 172 GLU D OE1 1 
ATOM   6788 O OE2 . GLU D 1 170 ? -1.747  -11.393 -70.940 1.00 22.67 ? 172 GLU D OE2 1 
ATOM   6789 N N   . ASP D 1 171 ? -4.366  -17.485 -69.967 1.00 19.93 ? 173 ASP D N   1 
ATOM   6790 C CA  . ASP D 1 171 ? -4.253  -18.935 -70.123 1.00 24.83 ? 173 ASP D CA  1 
ATOM   6791 C C   . ASP D 1 171 ? -4.984  -19.715 -69.042 1.00 24.47 ? 173 ASP D C   1 
ATOM   6792 O O   . ASP D 1 171 ? -4.732  -20.915 -68.862 1.00 21.19 ? 173 ASP D O   1 
ATOM   6793 C CB  . ASP D 1 171 ? -2.788  -19.375 -70.187 1.00 25.28 ? 173 ASP D CB  1 
ATOM   6794 C CG  . ASP D 1 171 ? -2.048  -18.733 -71.345 1.00 24.09 ? 173 ASP D CG  1 
ATOM   6795 O OD1 . ASP D 1 171 ? -2.697  -18.460 -72.366 1.00 29.86 ? 173 ASP D OD1 1 
ATOM   6796 O OD2 . ASP D 1 171 ? -0.847  -18.449 -71.194 1.00 31.83 ? 173 ASP D OD2 1 
ATOM   6797 N N   . GLY D 1 172 ? -5.961  -19.079 -68.391 1.00 25.82 ? 174 GLY D N   1 
ATOM   6798 C CA  . GLY D 1 172 ? -6.907  -19.773 -67.557 1.00 25.93 ? 174 GLY D CA  1 
ATOM   6799 C C   . GLY D 1 172 ? -7.023  -19.437 -66.090 1.00 29.08 ? 174 GLY D C   1 
ATOM   6800 O O   . GLY D 1 172 ? -6.107  -19.133 -65.472 1.00 35.99 ? 174 GLY D O   1 
ATOM   6801 N N   . GLY D 1 173 ? -8.176  -19.556 -65.511 1.00 25.26 ? 175 GLY D N   1 
ATOM   6802 C CA  . GLY D 1 173 ? -8.203  -19.315 -64.094 1.00 24.99 ? 175 GLY D CA  1 
ATOM   6803 C C   . GLY D 1 173 ? -8.587  -17.902 -63.778 1.00 23.91 ? 175 GLY D C   1 
ATOM   6804 O O   . GLY D 1 173 ? -8.666  -17.073 -64.630 1.00 18.82 ? 175 GLY D O   1 
ATOM   6805 N N   . VAL D 1 174 ? -8.800  -17.667 -62.507 1.00 20.52 ? 176 VAL D N   1 
ATOM   6806 C CA  . VAL D 1 174 ? -9.275  -16.412 -62.045 1.00 22.70 ? 176 VAL D CA  1 
ATOM   6807 C C   . VAL D 1 174 ? -8.489  -15.970 -60.833 1.00 23.00 ? 176 VAL D C   1 
ATOM   6808 O O   . VAL D 1 174 ? -8.128  -16.753 -60.020 1.00 23.61 ? 176 VAL D O   1 
ATOM   6809 C CB  . VAL D 1 174 ? -10.756 -16.569 -61.713 1.00 32.21 ? 176 VAL D CB  1 
ATOM   6810 C CG1 . VAL D 1 174 ? -11.042 -16.024 -60.456 1.00 33.66 ? 176 VAL D CG1 1 
ATOM   6811 C CG2 . VAL D 1 174 ? -11.609 -15.960 -62.797 1.00 30.02 ? 176 VAL D CG2 1 
ATOM   6812 N N   . GLN D 1 175 ? -8.221  -14.688 -60.766 1.00 18.39 ? 177 GLN D N   1 
ATOM   6813 C CA  . GLN D 1 175 ? -7.483  -14.057 -59.673 1.00 17.78 ? 177 GLN D CA  1 
ATOM   6814 C C   . GLN D 1 175 ? -8.450  -13.223 -58.840 1.00 17.11 ? 177 GLN D C   1 
ATOM   6815 O O   . GLN D 1 175 ? -8.962  -12.205 -59.308 1.00 15.08 ? 177 GLN D O   1 
ATOM   6816 C CB  . GLN D 1 175 ? -6.351  -13.197 -60.219 1.00 17.93 ? 177 GLN D CB  1 
ATOM   6817 C CG  . GLN D 1 175 ? -5.761  -12.237 -59.189 1.00 18.65 ? 177 GLN D CG  1 
ATOM   6818 C CD  . GLN D 1 175 ? -4.870  -12.922 -58.182 1.00 17.14 ? 177 GLN D CD  1 
ATOM   6819 O OE1 . GLN D 1 175 ? -3.826  -13.448 -58.536 1.00 19.39 ? 177 GLN D OE1 1 
ATOM   6820 N NE2 . GLN D 1 175 ? -5.259  -12.891 -56.912 1.00 17.59 ? 177 GLN D NE2 1 
ATOM   6821 N N   . LEU D 1 176 ? -8.675  -13.636 -57.599 1.00 17.04 ? 178 LEU D N   1 
ATOM   6822 C CA  . LEU D 1 176 ? -9.628  -12.956 -56.739 1.00 13.02 ? 178 LEU D CA  1 
ATOM   6823 C C   . LEU D 1 176 ? -9.028  -11.672 -56.179 1.00 14.33 ? 178 LEU D C   1 
ATOM   6824 O O   . LEU D 1 176 ? -7.846  -11.632 -55.825 1.00 14.06 ? 178 LEU D O   1 
ATOM   6825 C CB  . LEU D 1 176 ? -10.041 -13.881 -55.598 1.00 17.81 ? 178 LEU D CB  1 
ATOM   6826 C CG  . LEU D 1 176 ? -11.084 -13.292 -54.662 1.00 26.11 ? 178 LEU D CG  1 
ATOM   6827 C CD1 . LEU D 1 176 ? -12.438 -13.415 -55.337 1.00 29.03 ? 178 LEU D CD1 1 
ATOM   6828 C CD2 . LEU D 1 176 ? -11.075 -14.003 -53.307 1.00 28.94 ? 178 LEU D CD2 1 
ATOM   6829 N N   . ALA D 1 177 ? -9.854  -10.617 -56.122 1.00 14.27 ? 179 ALA D N   1 
ATOM   6830 C CA  . ALA D 1 177 ? -9.502  -9.326  -55.522 1.00 12.60 ? 179 ALA D CA  1 
ATOM   6831 C C   . ALA D 1 177 ? -10.605 -8.978  -54.524 1.00 12.93 ? 179 ALA D C   1 
ATOM   6832 O O   . ALA D 1 177 ? -11.702 -8.561  -54.914 1.00 15.27 ? 179 ALA D O   1 
ATOM   6833 C CB  . ALA D 1 177 ? -9.355  -8.238  -56.585 1.00 11.26 ? 179 ALA D CB  1 
ATOM   6834 N N   . ASP D 1 178 ? -10.310 -9.125  -53.238 1.00 14.31 ? 180 ASP D N   1 
ATOM   6835 C CA  . ASP D 1 178 ? -11.319 -9.012  -52.183 1.00 15.93 ? 180 ASP D CA  1 
ATOM   6836 C C   . ASP D 1 178 ? -11.310 -7.569  -51.694 1.00 13.09 ? 180 ASP D C   1 
ATOM   6837 O O   . ASP D 1 178 ? -10.316 -7.123  -51.103 1.00 12.03 ? 180 ASP D O   1 
ATOM   6838 C CB  . ASP D 1 178 ? -10.991 -10.005 -51.062 1.00 14.25 ? 180 ASP D CB  1 
ATOM   6839 C CG  . ASP D 1 178 ? -12.102 -10.150 -50.035 1.00 25.08 ? 180 ASP D CG  1 
ATOM   6840 O OD1 . ASP D 1 178 ? -13.197 -9.564  -50.210 1.00 23.84 ? 180 ASP D OD1 1 
ATOM   6841 O OD2 . ASP D 1 178 ? -11.880 -10.890 -49.043 1.00 27.03 ? 180 ASP D OD2 1 
ATOM   6842 N N   . HIS D 1 179 ? -12.401 -6.832  -51.966 1.00 13.33 ? 181 HIS D N   1 
ATOM   6843 C CA  . HIS D 1 179 ? -12.502 -5.395  -51.716 1.00 12.27 ? 181 HIS D CA  1 
ATOM   6844 C C   . HIS D 1 179 ? -13.218 -5.110  -50.402 1.00 12.34 ? 181 HIS D C   1 
ATOM   6845 O O   . HIS D 1 179 ? -14.315 -5.624  -50.171 1.00 14.84 ? 181 HIS D O   1 
ATOM   6846 C CB  . HIS D 1 179 ? -13.300 -4.696  -52.828 1.00 11.01 ? 181 HIS D CB  1 
ATOM   6847 C CG  . HIS D 1 179 ? -12.570 -4.566  -54.128 1.00 10.59 ? 181 HIS D CG  1 
ATOM   6848 N ND1 . HIS D 1 179 ? -12.166 -5.656  -54.868 1.00 10.28 ? 181 HIS D ND1 1 
ATOM   6849 C CD2 . HIS D 1 179 ? -12.237 -3.472  -54.854 1.00 10.81 ? 181 HIS D CD2 1 
ATOM   6850 C CE1 . HIS D 1 179 ? -11.595 -5.236  -55.985 1.00 10.53 ? 181 HIS D CE1 1 
ATOM   6851 N NE2 . HIS D 1 179 ? -11.612 -3.916  -55.995 1.00 10.80 ? 181 HIS D NE2 1 
ATOM   6852 N N   . TYR D 1 180 ? -12.630 -4.239  -49.582 1.00 10.84 ? 182 TYR D N   1 
ATOM   6853 C CA  . TYR D 1 180 ? -13.284 -3.670  -48.408 1.00 12.61 ? 182 TYR D CA  1 
ATOM   6854 C C   . TYR D 1 180 ? -13.317 -2.162  -48.584 1.00 12.92 ? 182 TYR D C   1 
ATOM   6855 O O   . TYR D 1 180 ? -12.305 -1.573  -48.949 1.00 12.92 ? 182 TYR D O   1 
ATOM   6856 C CB  . TYR D 1 180 ? -12.530 -4.049  -47.127 1.00 13.48 ? 182 TYR D CB  1 
ATOM   6857 C CG  . TYR D 1 180 ? -12.527 -5.547  -46.906 1.00 13.23 ? 182 TYR D CG  1 
ATOM   6858 C CD1 . TYR D 1 180 ? -11.653 -6.373  -47.600 1.00 14.26 ? 182 TYR D CD1 1 
ATOM   6859 C CD2 . TYR D 1 180 ? -13.412 -6.131  -46.009 1.00 13.81 ? 182 TYR D CD2 1 
ATOM   6860 C CE1 . TYR D 1 180 ? -11.672 -7.753  -47.416 1.00 15.77 ? 182 TYR D CE1 1 
ATOM   6861 C CE2 . TYR D 1 180 ? -13.440 -7.497  -45.817 1.00 16.16 ? 182 TYR D CE2 1 
ATOM   6862 C CZ  . TYR D 1 180 ? -12.563 -8.303  -46.515 1.00 18.52 ? 182 TYR D CZ  1 
ATOM   6863 O OH  . TYR D 1 180 ? -12.589 -9.665  -46.326 1.00 19.82 ? 182 TYR D OH  1 
ATOM   6864 N N   . GLN D 1 181 ? -14.459 -1.536  -48.318 1.00 13.10 ? 183 GLN D N   1 
ATOM   6865 C CA  . GLN D 1 181 ? -14.630 -0.128  -48.672 1.00 12.86 ? 183 GLN D CA  1 
ATOM   6866 C C   . GLN D 1 181 ? -15.341 0.630   -47.568 1.00 13.73 ? 183 GLN D C   1 
ATOM   6867 O O   . GLN D 1 181 ? -16.287 0.118   -46.971 1.00 13.75 ? 183 GLN D O   1 
ATOM   6868 C CB  . GLN D 1 181 ? -15.416 -0.006  -49.977 1.00 11.91 ? 183 GLN D CB  1 
ATOM   6869 C CG  . GLN D 1 181 ? -15.663 1.430   -50.463 1.00 12.86 ? 183 GLN D CG  1 
ATOM   6870 C CD  . GLN D 1 181 ? -16.561 1.480   -51.684 1.00 12.69 ? 183 GLN D CD  1 
ATOM   6871 O OE1 . GLN D 1 181 ? -16.656 0.506   -52.436 1.00 13.11 ? 183 GLN D OE1 1 
ATOM   6872 N NE2 . GLN D 1 181 ? -17.217 2.608   -51.890 1.00 12.94 ? 183 GLN D NE2 1 
ATOM   6873 N N   . GLN D 1 182 ? -14.901 1.859   -47.308 1.00 15.00 ? 184 GLN D N   1 
ATOM   6874 C CA  . GLN D 1 182 ? -15.738 2.727   -46.499 1.00 15.68 ? 184 GLN D CA  1 
ATOM   6875 C C   . GLN D 1 182 ? -15.638 4.150   -47.011 1.00 15.44 ? 184 GLN D C   1 
ATOM   6876 O O   . GLN D 1 182 ? -14.561 4.615   -47.402 1.00 15.66 ? 184 GLN D O   1 
ATOM   6877 C CB  . GLN D 1 182 ? -15.386 2.692   -45.011 1.00 21.69 ? 184 GLN D CB  1 
ATOM   6878 C CG  . GLN D 1 182 ? -13.961 2.925   -44.681 1.00 25.23 ? 184 GLN D CG  1 
ATOM   6879 C CD  . GLN D 1 182 ? -13.788 3.168   -43.189 1.00 37.62 ? 184 GLN D CD  1 
ATOM   6880 O OE1 . GLN D 1 182 ? -14.671 2.838   -42.389 1.00 39.52 ? 184 GLN D OE1 1 
ATOM   6881 N NE2 . GLN D 1 182 ? -12.661 3.771   -42.811 1.00 39.67 ? 184 GLN D NE2 1 
ATOM   6882 N N   . ASN D 1 183 ? -16.776 4.825   -47.013 1.00 15.62 ? 185 ASN D N   1 
ATOM   6883 C CA  . ASN D 1 183 ? -16.866 6.209   -47.449 1.00 15.28 ? 185 ASN D CA  1 
ATOM   6884 C C   . ASN D 1 183 ? -17.420 7.062   -46.324 1.00 15.87 ? 185 ASN D C   1 
ATOM   6885 O O   . ASN D 1 183 ? -18.315 6.632   -45.591 1.00 16.84 ? 185 ASN D O   1 
ATOM   6886 C CB  . ASN D 1 183 ? -17.750 6.369   -48.683 1.00 12.19 ? 185 ASN D CB  1 
ATOM   6887 C CG  . ASN D 1 183 ? -17.211 5.642   -49.887 1.00 16.51 ? 185 ASN D CG  1 
ATOM   6888 O OD1 . ASN D 1 183 ? -16.792 4.493   -49.811 1.00 16.63 ? 185 ASN D OD1 1 
ATOM   6889 N ND2 . ASN D 1 183 ? -17.233 6.321   -51.027 1.00 13.91 ? 185 ASN D ND2 1 
ATOM   6890 N N   . THR D 1 184 ? -16.874 8.268   -46.202 1.00 15.00 ? 186 THR D N   1 
ATOM   6891 C CA  . THR D 1 184 ? -17.283 9.265   -45.218 1.00 17.46 ? 186 THR D CA  1 
ATOM   6892 C C   . THR D 1 184 ? -17.351 10.641  -45.873 1.00 16.98 ? 186 THR D C   1 
ATOM   6893 O O   . THR D 1 184 ? -16.522 10.962  -46.734 1.00 17.92 ? 186 THR D O   1 
ATOM   6894 C CB  . THR D 1 184 ? -16.298 9.286   -44.034 1.00 19.97 ? 186 THR D CB  1 
ATOM   6895 O OG1 . THR D 1 184 ? -15.020 9.699   -44.501 1.00 24.20 ? 186 THR D OG1 1 
ATOM   6896 C CG2 . THR D 1 184 ? -16.157 7.918   -43.396 1.00 24.38 ? 186 THR D CG2 1 
ATOM   6897 N N   . PRO D 1 185 ? -18.319 11.471  -45.499 1.00 19.67 ? 187 PRO D N   1 
ATOM   6898 C CA  . PRO D 1 185 ? -18.429 12.794  -46.121 1.00 19.38 ? 187 PRO D CA  1 
ATOM   6899 C C   . PRO D 1 185 ? -17.275 13.690  -45.705 1.00 19.76 ? 187 PRO D C   1 
ATOM   6900 O O   . PRO D 1 185 ? -16.729 13.567  -44.605 1.00 20.80 ? 187 PRO D O   1 
ATOM   6901 C CB  . PRO D 1 185 ? -19.763 13.342  -45.595 1.00 23.94 ? 187 PRO D CB  1 
ATOM   6902 C CG  . PRO D 1 185 ? -20.138 12.484  -44.425 1.00 28.51 ? 187 PRO D CG  1 
ATOM   6903 C CD  . PRO D 1 185 ? -19.342 11.218  -44.466 1.00 23.81 ? 187 PRO D CD  1 
ATOM   6904 N N   . ILE D 1 186 ? -16.903 14.591  -46.614 1.00 17.43 ? 188 ILE D N   1 
ATOM   6905 C CA  . ILE D 1 186 ? -15.906 15.617  -46.325 1.00 19.98 ? 188 ILE D CA  1 
ATOM   6906 C C   . ILE D 1 186 ? -16.551 16.818  -45.626 1.00 27.56 ? 188 ILE D C   1 
ATOM   6907 O O   . ILE D 1 186 ? -15.983 17.385  -44.683 1.00 28.07 ? 188 ILE D O   1 
ATOM   6908 C CB  . ILE D 1 186 ? -15.196 16.035  -47.630 1.00 20.59 ? 188 ILE D CB  1 
ATOM   6909 C CG1 . ILE D 1 186 ? -14.339 14.881  -48.167 1.00 18.97 ? 188 ILE D CG1 1 
ATOM   6910 C CG2 . ILE D 1 186 ? -14.309 17.265  -47.400 1.00 22.85 ? 188 ILE D CG2 1 
ATOM   6911 C CD1 . ILE D 1 186 ? -13.717 15.145  -49.524 1.00 15.81 ? 188 ILE D CD1 1 
ATOM   6912 N N   . GLY D 1 187 ? -17.746 17.221  -46.071 1.00 26.04 ? 189 GLY D N   1 
ATOM   6913 C CA  . GLY D 1 187 ? -18.427 18.340  -45.450 1.00 37.42 ? 189 GLY D CA  1 
ATOM   6914 C C   . GLY D 1 187 ? -19.131 17.975  -44.149 1.00 42.42 ? 189 GLY D C   1 
ATOM   6915 O O   . GLY D 1 187 ? -19.345 16.805  -43.817 1.00 37.76 ? 189 GLY D O   1 
ATOM   6916 N N   . ASP D 1 188 ? -19.494 19.017  -43.395 1.00 45.34 ? 190 ASP D N   1 
ATOM   6917 C CA  . ASP D 1 188 ? -20.250 18.858  -42.159 1.00 48.61 ? 190 ASP D CA  1 
ATOM   6918 C C   . ASP D 1 188 ? -21.753 18.865  -42.372 1.00 53.08 ? 190 ASP D C   1 
ATOM   6919 O O   . ASP D 1 188 ? -22.491 18.495  -41.451 1.00 55.36 ? 190 ASP D O   1 
ATOM   6920 C CB  . ASP D 1 188 ? -19.893 19.968  -41.172 1.00 50.26 ? 190 ASP D CB  1 
ATOM   6921 C CG  . ASP D 1 188 ? -18.462 19.904  -40.739 1.00 53.94 ? 190 ASP D CG  1 
ATOM   6922 O OD1 . ASP D 1 188 ? -18.151 19.094  -39.840 1.00 60.53 ? 190 ASP D OD1 1 
ATOM   6923 O OD2 . ASP D 1 188 ? -17.643 20.653  -41.310 1.00 57.09 ? 190 ASP D OD2 1 
ATOM   6924 N N   . GLY D 1 189 ? -22.221 19.274  -43.549 1.00 52.12 ? 191 GLY D N   1 
ATOM   6925 C CA  . GLY D 1 189 ? -23.634 19.383  -43.818 1.00 54.23 ? 191 GLY D CA  1 
ATOM   6926 C C   . GLY D 1 189 ? -24.375 18.073  -43.649 1.00 56.12 ? 191 GLY D C   1 
ATOM   6927 O O   . GLY D 1 189 ? -23.776 17.001  -43.501 1.00 53.95 ? 191 GLY D O   1 
ATOM   6928 N N   . PRO D 1 190 ? -25.705 18.138  -43.655 1.00 58.59 ? 192 PRO D N   1 
ATOM   6929 C CA  . PRO D 1 190 ? -26.492 16.904  -43.600 1.00 56.66 ? 192 PRO D CA  1 
ATOM   6930 C C   . PRO D 1 190 ? -26.293 16.101  -44.870 1.00 55.49 ? 192 PRO D C   1 
ATOM   6931 O O   . PRO D 1 190 ? -26.206 16.654  -45.970 1.00 57.79 ? 192 PRO D O   1 
ATOM   6932 C CB  . PRO D 1 190 ? -27.934 17.406  -43.472 1.00 57.88 ? 192 PRO D CB  1 
ATOM   6933 C CG  . PRO D 1 190 ? -27.913 18.738  -44.146 1.00 58.80 ? 192 PRO D CG  1 
ATOM   6934 C CD  . PRO D 1 190 ? -26.552 19.327  -43.855 1.00 57.75 ? 192 PRO D CD  1 
ATOM   6935 N N   . VAL D 1 191 ? -26.210 14.787  -44.712 1.00 53.20 ? 193 VAL D N   1 
ATOM   6936 C CA  . VAL D 1 191 ? -25.959 13.901  -45.837 1.00 50.16 ? 193 VAL D CA  1 
ATOM   6937 C C   . VAL D 1 191 ? -26.877 12.695  -45.702 1.00 50.98 ? 193 VAL D C   1 
ATOM   6938 O O   . VAL D 1 191 ? -27.007 12.113  -44.620 1.00 50.98 ? 193 VAL D O   1 
ATOM   6939 C CB  . VAL D 1 191 ? -24.475 13.487  -45.898 1.00 46.82 ? 193 VAL D CB  1 
ATOM   6940 C CG1 . VAL D 1 191 ? -24.320 12.168  -46.621 1.00 42.85 ? 193 VAL D CG1 1 
ATOM   6941 C CG2 . VAL D 1 191 ? -23.644 14.585  -46.545 1.00 40.66 ? 193 VAL D CG2 1 
ATOM   6942 N N   . LEU D 1 192 ? -27.522 12.334  -46.806 1.00 51.12 ? 194 LEU D N   1 
ATOM   6943 C CA  . LEU D 1 192 ? -28.490 11.248  -46.813 1.00 50.74 ? 194 LEU D CA  1 
ATOM   6944 C C   . LEU D 1 192 ? -27.807 9.917   -46.535 1.00 47.93 ? 194 LEU D C   1 
ATOM   6945 O O   . LEU D 1 192 ? -26.761 9.612   -47.115 1.00 49.53 ? 194 LEU D O   1 
ATOM   6946 C CB  . LEU D 1 192 ? -29.190 11.202  -48.170 1.00 49.96 ? 194 LEU D CB  1 
ATOM   6947 C CG  . LEU D 1 192 ? -30.025 12.449  -48.459 1.00 52.31 ? 194 LEU D CG  1 
ATOM   6948 C CD1 . LEU D 1 192 ? -30.614 12.436  -49.872 1.00 49.29 ? 194 LEU D CD1 1 
ATOM   6949 C CD2 . LEU D 1 192 ? -31.113 12.576  -47.401 1.00 55.04 ? 194 LEU D CD2 1 
ATOM   6950 N N   . LEU D 1 193 ? -28.397 9.121   -45.648 1.00 46.74 ? 195 LEU D N   1 
ATOM   6951 C CA  . LEU D 1 193 ? -27.971 7.738   -45.487 1.00 43.97 ? 195 LEU D CA  1 
ATOM   6952 C C   . LEU D 1 193 ? -28.999 6.813   -46.109 1.00 46.17 ? 195 LEU D C   1 
ATOM   6953 O O   . LEU D 1 193 ? -30.168 6.807   -45.691 1.00 42.59 ? 195 LEU D O   1 
ATOM   6954 C CB  . LEU D 1 193 ? -27.748 7.389   -44.021 1.00 43.91 ? 195 LEU D CB  1 
ATOM   6955 C CG  . LEU D 1 193 ? -26.502 8.017   -43.400 1.00 45.66 ? 195 LEU D CG  1 
ATOM   6956 C CD1 . LEU D 1 193 ? -25.956 7.088   -42.353 1.00 45.17 ? 195 LEU D CD1 1 
ATOM   6957 C CD2 . LEU D 1 193 ? -25.439 8.245   -44.466 1.00 40.09 ? 195 LEU D CD2 1 
ATOM   6958 N N   . PRO D 1 194 ? -28.604 6.038   -47.113 1.00 45.93 ? 196 PRO D N   1 
ATOM   6959 C CA  . PRO D 1 194 ? -29.550 5.133   -47.767 1.00 44.08 ? 196 PRO D CA  1 
ATOM   6960 C C   . PRO D 1 194 ? -29.908 3.978   -46.856 1.00 42.14 ? 196 PRO D C   1 
ATOM   6961 O O   . PRO D 1 194 ? -29.146 3.606   -45.961 1.00 43.02 ? 196 PRO D O   1 
ATOM   6962 C CB  . PRO D 1 194 ? -28.761 4.634   -48.985 1.00 42.49 ? 196 PRO D CB  1 
ATOM   6963 C CG  . PRO D 1 194 ? -27.340 4.647   -48.504 1.00 40.27 ? 196 PRO D CG  1 
ATOM   6964 C CD  . PRO D 1 194 ? -27.257 5.935   -47.705 1.00 42.63 ? 196 PRO D CD  1 
ATOM   6965 N N   . ASP D 1 195 ? -31.082 3.404   -47.091 1.00 42.09 ? 197 ASP D N   1 
ATOM   6966 C CA  . ASP D 1 195 ? -31.228 2.008   -46.738 1.00 39.91 ? 197 ASP D CA  1 
ATOM   6967 C C   . ASP D 1 195 ? -30.282 1.196   -47.609 1.00 36.59 ? 197 ASP D C   1 
ATOM   6968 O O   . ASP D 1 195 ? -29.817 1.646   -48.662 1.00 34.26 ? 197 ASP D O   1 
ATOM   6969 C CB  . ASP D 1 195 ? -32.674 1.526   -46.902 1.00 42.80 ? 197 ASP D CB  1 
ATOM   6970 C CG  . ASP D 1 195 ? -33.658 2.298   -46.037 1.00 51.35 ? 197 ASP D CG  1 
ATOM   6971 O OD1 . ASP D 1 195 ? -34.872 2.209   -46.311 1.00 51.75 ? 197 ASP D OD1 1 
ATOM   6972 O OD2 . ASP D 1 195 ? -33.225 2.949   -45.057 1.00 50.46 ? 197 ASP D OD2 1 
ATOM   6973 N N   . ASN D 1 196 ? -29.966 0.000   -47.137 1.00 32.59 ? 198 ASN D N   1 
ATOM   6974 C CA  . ASN D 1 196 ? -29.024 -0.837  -47.850 1.00 28.07 ? 198 ASN D CA  1 
ATOM   6975 C C   . ASN D 1 196 ? -29.553 -1.136  -49.247 1.00 29.85 ? 198 ASN D C   1 
ATOM   6976 O O   . ASN D 1 196 ? -30.753 -1.354  -49.442 1.00 29.19 ? 198 ASN D O   1 
ATOM   6977 C CB  . ASN D 1 196 ? -28.786 -2.113  -47.056 1.00 31.11 ? 198 ASN D CB  1 
ATOM   6978 C CG  . ASN D 1 196 ? -28.223 -1.828  -45.675 1.00 28.92 ? 198 ASN D CG  1 
ATOM   6979 O OD1 . ASN D 1 196 ? -28.033 -0.668  -45.305 1.00 30.02 ? 198 ASN D OD1 1 
ATOM   6980 N ND2 . ASN D 1 196 ? -27.949 -2.876  -44.914 1.00 31.91 ? 198 ASN D ND2 1 
ATOM   6981 N N   . HIS D 1 197 ? -28.653 -1.106  -50.228 1.00 26.64 ? 199 HIS D N   1 
ATOM   6982 C CA  . HIS D 1 197 ? -29.026 -1.304  -51.620 1.00 23.65 ? 199 HIS D CA  1 
ATOM   6983 C C   . HIS D 1 197 ? -27.794 -1.758  -52.389 1.00 20.78 ? 199 HIS D C   1 
ATOM   6984 O O   . HIS D 1 197 ? -26.674 -1.731  -51.877 1.00 18.36 ? 199 HIS D O   1 
ATOM   6985 C CB  . HIS D 1 197 ? -29.596 -0.030  -52.240 1.00 22.79 ? 199 HIS D CB  1 
ATOM   6986 C CG  . HIS D 1 197 ? -28.605 1.088   -52.330 1.00 22.94 ? 199 HIS D CG  1 
ATOM   6987 N ND1 . HIS D 1 197 ? -28.258 1.864   -51.245 1.00 26.11 ? 199 HIS D ND1 1 
ATOM   6988 C CD2 . HIS D 1 197 ? -27.866 1.547   -53.370 1.00 19.35 ? 199 HIS D CD2 1 
ATOM   6989 C CE1 . HIS D 1 197 ? -27.363 2.764   -51.617 1.00 24.90 ? 199 HIS D CE1 1 
ATOM   6990 N NE2 . HIS D 1 197 ? -27.108 2.592   -52.901 1.00 22.05 ? 199 HIS D NE2 1 
ATOM   6991 N N   . TYR D 1 198 ? -28.019 -2.153  -53.637 1.00 16.72 ? 200 TYR D N   1 
ATOM   6992 C CA  . TYR D 1 198 ? -26.971 -2.648  -54.517 1.00 16.86 ? 200 TYR D CA  1 
ATOM   6993 C C   . TYR D 1 198 ? -26.621 -1.613  -55.577 1.00 17.51 ? 200 TYR D C   1 
ATOM   6994 O O   . TYR D 1 198 ? -27.470 -0.827  -56.001 1.00 18.75 ? 200 TYR D O   1 
ATOM   6995 C CB  . TYR D 1 198 ? -27.417 -3.920  -55.237 1.00 17.45 ? 200 TYR D CB  1 
ATOM   6996 C CG  . TYR D 1 198 ? -27.447 -5.149  -54.367 1.00 20.48 ? 200 TYR D CG  1 
ATOM   6997 C CD1 . TYR D 1 198 ? -26.291 -5.871  -54.110 1.00 21.06 ? 200 TYR D CD1 1 
ATOM   6998 C CD2 . TYR D 1 198 ? -28.630 -5.574  -53.791 1.00 26.28 ? 200 TYR D CD2 1 
ATOM   6999 C CE1 . TYR D 1 198 ? -26.322 -6.997  -53.313 1.00 25.55 ? 200 TYR D CE1 1 
ATOM   7000 C CE2 . TYR D 1 198 ? -28.665 -6.695  -52.993 1.00 27.77 ? 200 TYR D CE2 1 
ATOM   7001 C CZ  . TYR D 1 198 ? -27.515 -7.397  -52.761 1.00 25.01 ? 200 TYR D CZ  1 
ATOM   7002 O OH  . TYR D 1 198 ? -27.561 -8.511  -51.964 1.00 34.68 ? 200 TYR D OH  1 
ATOM   7003 N N   . LEU D 1 199 ? -25.371 -1.647  -56.034 1.00 14.74 ? 201 LEU D N   1 
ATOM   7004 C CA  . LEU D 1 199 ? -24.969 -0.973  -57.263 1.00 12.85 ? 201 LEU D CA  1 
ATOM   7005 C C   . LEU D 1 199 ? -24.559 -2.047  -58.256 1.00 14.87 ? 201 LEU D C   1 
ATOM   7006 O O   . LEU D 1 199 ? -23.771 -2.932  -57.915 1.00 13.68 ? 201 LEU D O   1 
ATOM   7007 C CB  . LEU D 1 199 ? -23.804 -0.010  -57.026 1.00 14.71 ? 201 LEU D CB  1 
ATOM   7008 C CG  . LEU D 1 199 ? -24.080 1.149   -56.062 1.00 17.77 ? 201 LEU D CG  1 
ATOM   7009 C CD1 . LEU D 1 199 ? -22.860 2.042   -55.947 1.00 18.50 ? 201 LEU D CD1 1 
ATOM   7010 C CD2 . LEU D 1 199 ? -25.274 1.964   -56.510 1.00 16.66 ? 201 LEU D CD2 1 
ATOM   7011 N N   . PHE D 1 200 ? -25.105 -1.975  -59.468 1.00 13.30 ? 202 PHE D N   1 
ATOM   7012 C CA  . PHE D 1 200 ? -24.829 -2.935  -60.531 1.00 13.55 ? 202 PHE D CA  1 
ATOM   7013 C C   . PHE D 1 200 ? -24.057 -2.238  -61.635 1.00 13.23 ? 202 PHE D C   1 
ATOM   7014 O O   . PHE D 1 200 ? -24.496 -1.195  -62.130 1.00 12.55 ? 202 PHE D O   1 
ATOM   7015 C CB  . PHE D 1 200 ? -26.142 -3.501  -61.076 1.00 12.60 ? 202 PHE D CB  1 
ATOM   7016 C CG  . PHE D 1 200 ? -26.853 -4.376  -60.092 1.00 15.98 ? 202 PHE D CG  1 
ATOM   7017 C CD1 . PHE D 1 200 ? -26.431 -5.682  -59.864 1.00 14.31 ? 202 PHE D CD1 1 
ATOM   7018 C CD2 . PHE D 1 200 ? -27.869 -3.860  -59.313 1.00 16.99 ? 202 PHE D CD2 1 
ATOM   7019 C CE1 . PHE D 1 200 ? -27.074 -6.473  -58.923 1.00 18.14 ? 202 PHE D CE1 1 
ATOM   7020 C CE2 . PHE D 1 200 ? -28.507 -4.644  -58.377 1.00 15.80 ? 202 PHE D CE2 1 
ATOM   7021 C CZ  . PHE D 1 200 ? -28.111 -5.949  -58.182 1.00 16.02 ? 202 PHE D CZ  1 
ATOM   7022 N N   . THR D 1 201 ? -22.914 -2.807  -62.022 1.00 13.10 ? 203 THR D N   1 
ATOM   7023 C CA  . THR D 1 201 ? -21.993 -2.137  -62.933 1.00 11.69 ? 203 THR D CA  1 
ATOM   7024 C C   . THR D 1 201 ? -21.691 -3.030  -64.134 1.00 14.43 ? 203 THR D C   1 
ATOM   7025 O O   . THR D 1 201 ? -21.602 -4.252  -64.003 1.00 12.46 ? 203 THR D O   1 
ATOM   7026 C CB  . THR D 1 201 ? -20.687 -1.758  -62.207 1.00 14.33 ? 203 THR D CB  1 
ATOM   7027 O OG1 . THR D 1 201 ? -20.978 -0.920  -61.076 1.00 15.60 ? 203 THR D OG1 1 
ATOM   7028 C CG2 . THR D 1 201 ? -19.704 -1.051  -63.139 1.00 16.22 ? 203 THR D CG2 1 
ATOM   7029 N N   . THR D 1 202 ? -21.554 -2.423  -65.312 1.00 15.52 ? 204 THR D N   1 
ATOM   7030 C CA  . THR D 1 202 ? -20.963 -3.109  -66.451 1.00 15.56 ? 204 THR D CA  1 
ATOM   7031 C C   . THR D 1 202 ? -19.821 -2.234  -66.959 1.00 16.43 ? 204 THR D C   1 
ATOM   7032 O O   . THR D 1 202 ? -19.986 -1.016  -67.113 1.00 15.59 ? 204 THR D O   1 
ATOM   7033 C CB  . THR D 1 202 ? -22.004 -3.409  -67.555 1.00 17.46 ? 204 THR D CB  1 
ATOM   7034 O OG1 . THR D 1 202 ? -21.341 -3.929  -68.720 1.00 19.69 ? 204 THR D OG1 1 
ATOM   7035 C CG2 . THR D 1 202 ? -22.742 -2.170  -67.956 1.00 21.39 ? 204 THR D CG2 1 
ATOM   7036 N N   . SER D 1 203 ? -18.654 -2.842  -67.159 1.00 15.21 ? 205 SER D N   1 
ATOM   7037 C CA  . SER D 1 203 ? -17.450 -2.131  -67.589 1.00 15.32 ? 205 SER D CA  1 
ATOM   7038 C C   . SER D 1 203 ? -16.915 -2.808  -68.841 1.00 17.82 ? 205 SER D C   1 
ATOM   7039 O O   . SER D 1 203 ? -16.833 -4.040  -68.893 1.00 15.78 ? 205 SER D O   1 
ATOM   7040 C CB  . SER D 1 203 ? -16.359 -2.153  -66.508 1.00 15.21 ? 205 SER D CB  1 
ATOM   7041 O OG  . SER D 1 203 ? -16.871 -1.804  -65.235 1.00 14.70 ? 205 SER D OG  1 
ATOM   7042 N N   . THR D 1 204 ? -16.549 -2.013  -69.845 1.00 16.61 ? 206 THR D N   1 
ATOM   7043 C CA  . THR D 1 204 ? -15.899 -2.526  -71.047 1.00 12.94 ? 206 THR D CA  1 
ATOM   7044 C C   . THR D 1 204 ? -14.590 -1.779  -71.236 1.00 13.44 ? 206 THR D C   1 
ATOM   7045 O O   . THR D 1 204 ? -14.584 -0.546  -71.288 1.00 13.84 ? 206 THR D O   1 
ATOM   7046 C CB  . THR D 1 204 ? -16.809 -2.383  -72.270 1.00 18.24 ? 206 THR D CB  1 
ATOM   7047 O OG1 . THR D 1 204 ? -18.090 -2.958  -71.967 1.00 17.80 ? 206 THR D OG1 1 
ATOM   7048 C CG2 . THR D 1 204 ? -16.198 -3.066  -73.495 1.00 18.41 ? 206 THR D CG2 1 
ATOM   7049 N N   . LEU D 1 205 ? -13.493 -2.526  -71.309 1.00 10.40 ? 207 LEU D N   1 
ATOM   7050 C CA  . LEU D 1 205 ? -12.154 -1.987  -71.476 1.00 12.56 ? 207 LEU D CA  1 
ATOM   7051 C C   . LEU D 1 205 ? -11.772 -2.049  -72.954 1.00 14.60 ? 207 LEU D C   1 
ATOM   7052 O O   . LEU D 1 205 ? -12.056 -3.040  -73.631 1.00 13.83 ? 207 LEU D O   1 
ATOM   7053 C CB  . LEU D 1 205 ? -11.140 -2.781  -70.655 1.00 13.86 ? 207 LEU D CB  1 
ATOM   7054 C CG  . LEU D 1 205 ? -11.395 -3.069  -69.167 1.00 17.32 ? 207 LEU D CG  1 
ATOM   7055 C CD1 . LEU D 1 205 ? -10.094 -3.489  -68.463 1.00 13.13 ? 207 LEU D CD1 1 
ATOM   7056 C CD2 . LEU D 1 205 ? -12.070 -1.919  -68.456 1.00 16.34 ? 207 LEU D CD2 1 
ATOM   7057 N N   . SER D 1 206 ? -11.131 -0.997  -73.455 1.00 11.91 ? 208 SER D N   1 
ATOM   7058 C CA  . SER D 1 206 ? -10.665 -1.010  -74.837 1.00 14.37 ? 208 SER D CA  1 
ATOM   7059 C C   . SER D 1 206 ? -9.409  -0.156  -74.945 1.00 15.63 ? 208 SER D C   1 
ATOM   7060 O O   . SER D 1 206 ? -8.881  0.341   -73.943 1.00 11.32 ? 208 SER D O   1 
ATOM   7061 C CB  . SER D 1 206 ? -11.745 -0.507  -75.801 1.00 15.95 ? 208 SER D CB  1 
ATOM   7062 O OG  . SER D 1 206 ? -12.172 0.784   -75.427 1.00 14.90 ? 208 SER D OG  1 
ATOM   7063 N N   . LYS D 1 207 ? -8.950  0.036   -76.178 1.00 14.95 ? 209 LYS D N   1 
ATOM   7064 C CA  . LYS D 1 207 ? -7.749  0.799   -76.463 1.00 13.23 ? 209 LYS D CA  1 
ATOM   7065 C C   . LYS D 1 207 ? -8.054  1.863   -77.509 1.00 17.88 ? 209 LYS D C   1 
ATOM   7066 O O   . LYS D 1 207 ? -8.951  1.712   -78.345 1.00 19.44 ? 209 LYS D O   1 
ATOM   7067 C CB  . LYS D 1 207 ? -6.611  -0.103  -76.962 1.00 14.97 ? 209 LYS D CB  1 
ATOM   7068 C CG  . LYS D 1 207 ? -6.133  -1.148  -75.975 1.00 15.73 ? 209 LYS D CG  1 
ATOM   7069 C CD  . LYS D 1 207 ? -5.330  -0.527  -74.810 1.00 12.69 ? 209 LYS D CD  1 
ATOM   7070 C CE  . LYS D 1 207 ? -4.713  -1.629  -73.950 1.00 14.89 ? 209 LYS D CE  1 
ATOM   7071 N NZ  . LYS D 1 207 ? -4.079  -1.062  -72.700 1.00 13.18 ? 209 LYS D NZ  1 
ATOM   7072 N N   . ASP D 1 208 ? -7.298  2.955   -77.428 1.00 14.23 ? 210 ASP D N   1 
ATOM   7073 C CA  . ASP D 1 208 ? -7.320  4.018   -78.419 1.00 15.45 ? 210 ASP D CA  1 
ATOM   7074 C C   . ASP D 1 208 ? -6.239  3.696   -79.445 1.00 17.15 ? 210 ASP D C   1 
ATOM   7075 O O   . ASP D 1 208 ? -5.051  3.669   -79.089 1.00 16.01 ? 210 ASP D O   1 
ATOM   7076 C CB  . ASP D 1 208 ? -7.064  5.358   -77.729 1.00 16.28 ? 210 ASP D CB  1 
ATOM   7077 C CG  . ASP D 1 208 ? -6.914  6.514   -78.685 1.00 20.96 ? 210 ASP D CG  1 
ATOM   7078 O OD1 . ASP D 1 208 ? -6.943  6.318   -79.923 1.00 19.50 ? 210 ASP D OD1 1 
ATOM   7079 O OD2 . ASP D 1 208 ? -6.743  7.641   -78.176 1.00 16.43 ? 210 ASP D OD2 1 
ATOM   7080 N N   . PRO D 1 209 ? -6.590  3.415   -80.705 1.00 19.28 ? 211 PRO D N   1 
ATOM   7081 C CA  . PRO D 1 209 ? -5.588  2.898   -81.651 1.00 18.76 ? 211 PRO D CA  1 
ATOM   7082 C C   . PRO D 1 209 ? -4.522  3.910   -82.037 1.00 18.01 ? 211 PRO D C   1 
ATOM   7083 O O   . PRO D 1 209 ? -3.519  3.513   -82.636 1.00 20.79 ? 211 PRO D O   1 
ATOM   7084 C CB  . PRO D 1 209 ? -6.423  2.490   -82.879 1.00 24.22 ? 211 PRO D CB  1 
ATOM   7085 C CG  . PRO D 1 209 ? -7.839  2.841   -82.569 1.00 25.35 ? 211 PRO D CG  1 
ATOM   7086 C CD  . PRO D 1 209 ? -7.882  3.692   -81.351 1.00 24.25 ? 211 PRO D CD  1 
ATOM   7087 N N   . ASN D 1 210 ? -4.712  5.182   -81.719 1.00 16.93 ? 212 ASN D N   1 
ATOM   7088 C CA  . ASN D 1 210 ? -3.747  6.232   -81.994 1.00 19.07 ? 212 ASN D CA  1 
ATOM   7089 C C   . ASN D 1 210 ? -2.964  6.665   -80.763 1.00 25.76 ? 212 ASN D C   1 
ATOM   7090 O O   . ASN D 1 210 ? -2.201  7.630   -80.851 1.00 23.16 ? 212 ASN D O   1 
ATOM   7091 C CB  . ASN D 1 210 ? -4.471  7.443   -82.586 1.00 23.37 ? 212 ASN D CB  1 
ATOM   7092 C CG  . ASN D 1 210 ? -5.007  7.170   -83.971 1.00 26.96 ? 212 ASN D CG  1 
ATOM   7093 O OD1 . ASN D 1 210 ? -4.433  6.387   -84.719 1.00 26.86 ? 212 ASN D OD1 1 
ATOM   7094 N ND2 . ASN D 1 210 ? -6.150  7.762   -84.292 1.00 29.33 ? 212 ASN D ND2 1 
ATOM   7095 N N   . GLU D 1 211 ? -3.155  6.014   -79.615 1.00 19.79 ? 213 GLU D N   1 
ATOM   7096 C CA  . GLU D 1 211 ? -2.492  6.403   -78.377 1.00 24.01 ? 213 GLU D CA  1 
ATOM   7097 C C   . GLU D 1 211 ? -1.241  5.547   -78.205 1.00 21.44 ? 213 GLU D C   1 
ATOM   7098 O O   . GLU D 1 211 ? -1.337  4.320   -78.107 1.00 22.13 ? 213 GLU D O   1 
ATOM   7099 C CB  . GLU D 1 211 ? -3.443  6.236   -77.185 1.00 16.87 ? 213 GLU D CB  1 
ATOM   7100 C CG  . GLU D 1 211 ? -2.793  6.560   -75.864 1.00 20.71 ? 213 GLU D CG  1 
ATOM   7101 C CD  . GLU D 1 211 ? -2.303  7.997   -75.834 1.00 22.12 ? 213 GLU D CD  1 
ATOM   7102 O OE1 . GLU D 1 211 ? -3.148  8.912   -75.848 1.00 21.51 ? 213 GLU D OE1 1 
ATOM   7103 O OE2 . GLU D 1 211 ? -1.070  8.205   -75.830 1.00 21.79 ? 213 GLU D OE2 1 
ATOM   7104 N N   . LYS D 1 212 ? -0.067  6.178   -78.185 1.00 22.90 ? 214 LYS D N   1 
ATOM   7105 C CA  . LYS D 1 212 ? 1.164   5.403   -78.011 1.00 23.81 ? 214 LYS D CA  1 
ATOM   7106 C C   . LYS D 1 212 ? 1.495   5.137   -76.548 1.00 20.35 ? 214 LYS D C   1 
ATOM   7107 O O   . LYS D 1 212 ? 2.301   4.249   -76.246 1.00 20.39 ? 214 LYS D O   1 
ATOM   7108 C CB  . LYS D 1 212 ? 2.391   6.098   -78.627 1.00 27.25 ? 214 LYS D CB  1 
ATOM   7109 C CG  . LYS D 1 212 ? 2.906   7.399   -77.954 1.00 34.70 ? 214 LYS D CG  1 
ATOM   7110 C CD  . LYS D 1 212 ? 1.865   8.479   -77.679 1.00 36.12 ? 214 LYS D CD  1 
ATOM   7111 C CE  . LYS D 1 212 ? 2.466   9.742   -77.042 1.00 34.00 ? 214 LYS D CE  1 
ATOM   7112 N NZ  . LYS D 1 212 ? 1.298   10.555  -76.559 1.00 38.50 ? 214 LYS D NZ  1 
ATOM   7113 N N   . ARG D 1 213 ? 0.912   5.890   -75.643 1.00 18.41 ? 215 ARG D N   1 
ATOM   7114 C CA  . ARG D 1 213 ? 1.211   5.715   -74.237 1.00 19.99 ? 215 ARG D CA  1 
ATOM   7115 C C   . ARG D 1 213 ? 0.380   4.580   -73.637 1.00 17.34 ? 215 ARG D C   1 
ATOM   7116 O O   . ARG D 1 213 ? -0.673  4.206   -74.151 1.00 16.21 ? 215 ARG D O   1 
ATOM   7117 C CB  . ARG D 1 213 ? 0.944   7.016   -73.506 1.00 20.05 ? 215 ARG D CB  1 
ATOM   7118 C CG  . ARG D 1 213 ? 2.019   8.058   -73.770 1.00 26.83 ? 215 ARG D CG  1 
ATOM   7119 C CD  . ARG D 1 213 ? 1.792   9.255   -72.909 1.00 29.99 ? 215 ARG D CD  1 
ATOM   7120 N NE  . ARG D 1 213 ? 0.633   10.044  -73.297 1.00 32.48 ? 215 ARG D NE  1 
ATOM   7121 C CZ  . ARG D 1 213 ? 0.366   11.237  -72.779 1.00 38.25 ? 215 ARG D CZ  1 
ATOM   7122 N NH1 . ARG D 1 213 ? 1.133   11.762  -71.832 1.00 35.07 ? 215 ARG D NH1 1 
ATOM   7123 N NH2 . ARG D 1 213 ? -0.707  11.908  -73.202 1.00 35.16 ? 215 ARG D NH2 1 
ATOM   7124 N N   . ASP D 1 214 ? 0.865   4.047   -72.524 1.00 16.61 ? 216 ASP D N   1 
ATOM   7125 C CA  . ASP D 1 214 ? 0.135   3.004   -71.804 1.00 14.67 ? 216 ASP D CA  1 
ATOM   7126 C C   . ASP D 1 214 ? -1.185  3.559   -71.298 1.00 13.46 ? 216 ASP D C   1 
ATOM   7127 O O   . ASP D 1 214 ? -1.208  4.585   -70.621 1.00 13.54 ? 216 ASP D O   1 
ATOM   7128 C CB  . ASP D 1 214 ? 0.993   2.482   -70.653 1.00 15.56 ? 216 ASP D CB  1 
ATOM   7129 C CG  . ASP D 1 214 ? 0.617   1.072   -70.228 1.00 17.82 ? 216 ASP D CG  1 
ATOM   7130 O OD1 . ASP D 1 214 ? -0.378  0.517   -70.764 1.00 15.02 ? 216 ASP D OD1 1 
ATOM   7131 O OD2 . ASP D 1 214 ? 1.336   0.509   -69.367 1.00 16.28 ? 216 ASP D OD2 1 
ATOM   7132 N N   . HIS D 1 215 ? -2.298  2.914   -71.655 1.00 13.00 ? 217 HIS D N   1 
ATOM   7133 C CA  . HIS D 1 215 ? -3.583  3.560   -71.426 1.00 11.94 ? 217 HIS D CA  1 
ATOM   7134 C C   . HIS D 1 215 ? -4.703  2.525   -71.358 1.00 12.66 ? 217 HIS D C   1 
ATOM   7135 O O   . HIS D 1 215 ? -4.513  1.340   -71.645 1.00 12.16 ? 217 HIS D O   1 
ATOM   7136 C CB  . HIS D 1 215 ? -3.865  4.588   -72.526 1.00 11.41 ? 217 HIS D CB  1 
ATOM   7137 C CG  . HIS D 1 215 ? -4.261  3.954   -73.822 1.00 11.42 ? 217 HIS D CG  1 
ATOM   7138 N ND1 . HIS D 1 215 ? -3.339  3.368   -74.659 1.00 12.03 ? 217 HIS D ND1 1 
ATOM   7139 C CD2 . HIS D 1 215 ? -5.464  3.818   -74.427 1.00 11.80 ? 217 HIS D CD2 1 
ATOM   7140 C CE1 . HIS D 1 215 ? -3.958  2.887   -75.723 1.00 16.97 ? 217 HIS D CE1 1 
ATOM   7141 N NE2 . HIS D 1 215 ? -5.249  3.136   -75.601 1.00 13.45 ? 217 HIS D NE2 1 
ATOM   7142 N N   . MET D 1 216 ? -5.881  3.015   -70.980 1.00 11.87 ? 218 MET D N   1 
ATOM   7143 C CA  . MET D 1 216 ? -7.106  2.222   -70.833 1.00 11.93 ? 218 MET D CA  1 
ATOM   7144 C C   . MET D 1 216 ? -8.275  3.123   -71.194 1.00 11.51 ? 218 MET D C   1 
ATOM   7145 O O   . MET D 1 216 ? -8.461  4.187   -70.579 1.00 11.86 ? 218 MET D O   1 
ATOM   7146 C CB  . MET D 1 216 ? -7.288  1.739   -69.397 1.00 13.36 ? 218 MET D CB  1 
ATOM   7147 C CG  . MET D 1 216 ? -8.712  1.281   -69.077 1.00 10.28 ? 218 MET D CG  1 
ATOM   7148 S SD  . MET D 1 216 ? -8.849  0.171   -67.658 1.00 15.18 ? 218 MET D SD  1 
ATOM   7149 C CE  . MET D 1 216 ? -8.954  1.461   -66.422 1.00 11.92 ? 218 MET D CE  1 
ATOM   7150 N N   . VAL D 1 217 ? -9.087  2.701   -72.165 1.00 10.10 ? 219 VAL D N   1 
ATOM   7151 C CA  . VAL D 1 217 ? -10.351 3.364   -72.460 1.00 9.61  ? 219 VAL D CA  1 
ATOM   7152 C C   . VAL D 1 217 ? -11.449 2.578   -71.761 1.00 10.31 ? 219 VAL D C   1 
ATOM   7153 O O   . VAL D 1 217 ? -11.454 1.343   -71.807 1.00 10.29 ? 219 VAL D O   1 
ATOM   7154 C CB  . VAL D 1 217 ? -10.600 3.448   -73.975 1.00 12.09 ? 219 VAL D CB  1 
ATOM   7155 C CG1 . VAL D 1 217 ? -11.932 4.165   -74.253 1.00 11.27 ? 219 VAL D CG1 1 
ATOM   7156 C CG2 . VAL D 1 217 ? -9.452  4.205   -74.636 1.00 11.62 ? 219 VAL D CG2 1 
ATOM   7157 N N   . LEU D 1 218 ? -12.349 3.277   -71.073 1.00 10.81 ? 220 LEU D N   1 
ATOM   7158 C CA  . LEU D 1 218 ? -13.320 2.608   -70.215 1.00 14.01 ? 220 LEU D CA  1 
ATOM   7159 C C   . LEU D 1 218 ? -14.713 3.144   -70.497 1.00 14.12 ? 220 LEU D C   1 
ATOM   7160 O O   . LEU D 1 218 ? -14.923 4.360   -70.525 1.00 14.42 ? 220 LEU D O   1 
ATOM   7161 C CB  . LEU D 1 218 ? -12.961 2.764   -68.717 1.00 13.68 ? 220 LEU D CB  1 
ATOM   7162 C CG  . LEU D 1 218 ? -14.052 2.373   -67.710 1.00 15.98 ? 220 LEU D CG  1 
ATOM   7163 C CD1 . LEU D 1 218 ? -14.199 0.883   -67.700 1.00 18.92 ? 220 LEU D CD1 1 
ATOM   7164 C CD2 . LEU D 1 218 ? -13.676 2.815   -66.312 1.00 19.49 ? 220 LEU D CD2 1 
ATOM   7165 N N   . LEU D 1 219 ? -15.659 2.239   -70.732 1.00 14.10 ? 221 LEU D N   1 
ATOM   7166 C CA  . LEU D 1 219 ? -17.065 2.606   -70.841 1.00 15.68 ? 221 LEU D CA  1 
ATOM   7167 C C   . LEU D 1 219 ? -17.787 1.850   -69.740 1.00 16.35 ? 221 LEU D C   1 
ATOM   7168 O O   . LEU D 1 219 ? -17.638 0.631   -69.625 1.00 15.23 ? 221 LEU D O   1 
ATOM   7169 C CB  . LEU D 1 219 ? -17.648 2.247   -72.212 1.00 14.95 ? 221 LEU D CB  1 
ATOM   7170 C CG  . LEU D 1 219 ? -19.172 2.130   -72.215 1.00 21.70 ? 221 LEU D CG  1 
ATOM   7171 C CD1 . LEU D 1 219 ? -19.751 3.548   -72.190 1.00 21.93 ? 221 LEU D CD1 1 
ATOM   7172 C CD2 . LEU D 1 219 ? -19.669 1.370   -73.457 1.00 22.77 ? 221 LEU D CD2 1 
ATOM   7173 N N   . GLU D 1 220 ? -18.548 2.566   -68.919 1.00 15.09 ? 222 GLU D N   1 
ATOM   7174 C CA  . GLU D 1 220 ? -19.104 1.957   -67.722 1.00 15.11 ? 222 GLU D CA  1 
ATOM   7175 C C   . GLU D 1 220 ? -20.525 2.449   -67.523 1.00 16.55 ? 222 GLU D C   1 
ATOM   7176 O O   . GLU D 1 220 ? -20.850 3.586   -67.882 1.00 17.52 ? 222 GLU D O   1 
ATOM   7177 C CB  . GLU D 1 220 ? -18.197 2.268   -66.519 1.00 17.88 ? 222 GLU D CB  1 
ATOM   7178 C CG  . GLU D 1 220 ? -18.469 1.529   -65.260 1.00 20.28 ? 222 GLU D CG  1 
ATOM   7179 C CD  . GLU D 1 220 ? -17.359 1.737   -64.231 1.00 24.05 ? 222 GLU D CD  1 
ATOM   7180 O OE1 . GLU D 1 220 ? -16.189 1.433   -64.537 1.00 28.23 ? 222 GLU D OE1 1 
ATOM   7181 O OE2 . GLU D 1 220 ? -17.644 2.260   -63.144 1.00 30.87 ? 222 GLU D OE2 1 
ATOM   7182 N N   . PHE D 1 221 ? -21.385 1.557   -67.019 1.00 16.11 ? 223 PHE D N   1 
ATOM   7183 C CA  . PHE D 1 221 ? -22.739 1.899   -66.615 1.00 15.59 ? 223 PHE D CA  1 
ATOM   7184 C C   . PHE D 1 221 ? -22.938 1.385   -65.203 1.00 15.12 ? 223 PHE D C   1 
ATOM   7185 O O   . PHE D 1 221 ? -22.498 0.279   -64.871 1.00 15.27 ? 223 PHE D O   1 
ATOM   7186 C CB  . PHE D 1 221 ? -23.810 1.292   -67.544 1.00 16.75 ? 223 PHE D CB  1 
ATOM   7187 C CG  . PHE D 1 221 ? -23.807 1.893   -68.895 1.00 17.07 ? 223 PHE D CG  1 
ATOM   7188 C CD1 . PHE D 1 221 ? -24.524 3.048   -69.153 1.00 19.04 ? 223 PHE D CD1 1 
ATOM   7189 C CD2 . PHE D 1 221 ? -23.048 1.326   -69.907 1.00 19.87 ? 223 PHE D CD2 1 
ATOM   7190 C CE1 . PHE D 1 221 ? -24.487 3.625   -70.403 1.00 19.87 ? 223 PHE D CE1 1 
ATOM   7191 C CE2 . PHE D 1 221 ? -23.013 1.899   -71.169 1.00 18.10 ? 223 PHE D CE2 1 
ATOM   7192 C CZ  . PHE D 1 221 ? -23.723 3.049   -71.408 1.00 20.94 ? 223 PHE D CZ  1 
ATOM   7193 N N   . VAL D 1 222 ? -23.550 2.204   -64.359 1.00 12.88 ? 224 VAL D N   1 
ATOM   7194 C CA  . VAL D 1 222 ? -23.791 1.805   -62.978 1.00 14.94 ? 224 VAL D CA  1 
ATOM   7195 C C   . VAL D 1 222 ? -25.202 2.216   -62.590 1.00 16.29 ? 224 VAL D C   1 
ATOM   7196 O O   . VAL D 1 222 ? -25.632 3.339   -62.860 1.00 14.73 ? 224 VAL D O   1 
ATOM   7197 C CB  . VAL D 1 222 ? -22.724 2.382   -62.021 1.00 20.26 ? 224 VAL D CB  1 
ATOM   7198 C CG1 . VAL D 1 222 ? -22.488 3.831   -62.298 1.00 26.57 ? 224 VAL D CG1 1 
ATOM   7199 C CG2 . VAL D 1 222 ? -23.153 2.178   -60.568 1.00 17.69 ? 224 VAL D CG2 1 
ATOM   7200 N N   . THR D 1 223 ? -25.956 1.287   -62.016 1.00 14.07 ? 225 THR D N   1 
ATOM   7201 C CA  . THR D 1 223 ? -27.308 1.640   -61.631 1.00 15.89 ? 225 THR D CA  1 
ATOM   7202 C C   . THR D 1 223 ? -27.654 0.974   -60.307 1.00 18.34 ? 225 THR D C   1 
ATOM   7203 O O   . THR D 1 223 ? -27.194 -0.134  -59.994 1.00 14.92 ? 225 THR D O   1 
ATOM   7204 C CB  . THR D 1 223 ? -28.322 1.318   -62.761 1.00 21.82 ? 225 THR D CB  1 
ATOM   7205 O OG1 . THR D 1 223 ? -29.465 0.618   -62.262 1.00 22.30 ? 225 THR D OG1 1 
ATOM   7206 C CG2 . THR D 1 223 ? -27.706 0.596   -63.907 1.00 12.19 ? 225 THR D CG2 1 
ATOM   7207 N N   . ALA D 1 224 ? -28.409 1.701   -59.505 1.00 18.45 ? 226 ALA D N   1 
ATOM   7208 C CA  . ALA D 1 224 ? -28.739 1.287   -58.154 1.00 18.30 ? 226 ALA D CA  1 
ATOM   7209 C C   . ALA D 1 224 ? -30.095 0.604   -58.134 1.00 19.34 ? 226 ALA D C   1 
ATOM   7210 O O   . ALA D 1 224 ? -30.956 0.881   -58.969 1.00 19.90 ? 226 ALA D O   1 
ATOM   7211 C CB  . ALA D 1 224 ? -28.752 2.495   -57.213 1.00 21.38 ? 226 ALA D CB  1 
ATOM   7212 N N   . ALA D 1 225 ? -30.281 -0.289  -57.164 1.00 17.55 ? 227 ALA D N   1 
ATOM   7213 C CA  . ALA D 1 225 ? -31.538 -1.003  -57.018 1.00 24.81 ? 227 ALA D CA  1 
ATOM   7214 C C   . ALA D 1 225 ? -31.690 -1.462  -55.577 1.00 26.47 ? 227 ALA D C   1 
ATOM   7215 O O   . ALA D 1 225 ? -30.706 -1.805  -54.914 1.00 26.23 ? 227 ALA D O   1 
ATOM   7216 C CB  . ALA D 1 225 ? -31.617 -2.198  -57.965 1.00 25.29 ? 227 ALA D CB  1 
ATOM   7217 N N   . GLY D 1 226 ? -32.936 -1.456  -55.098 1.00 35.79 ? 228 GLY D N   1 
ATOM   7218 C CA  . GLY D 1 226 ? -33.252 -1.782  -53.720 1.00 36.17 ? 228 GLY D CA  1 
ATOM   7219 C C   . GLY D 1 226 ? -33.378 -3.271  -53.469 1.00 45.20 ? 228 GLY D C   1 
ATOM   7220 O O   . GLY D 1 226 ? -32.858 -4.100  -54.219 1.00 46.07 ? 228 GLY D O   1 
ATOM   7221 N N   . ILE D 1 227 ? -34.110 -3.602  -52.397 1.00 51.80 ? 229 ILE D N   1 
ATOM   7222 C CA  . ILE D 1 227 ? -34.240 -4.952  -51.805 1.00 51.72 ? 229 ILE D CA  1 
ATOM   7223 C C   . ILE D 1 227 ? -32.876 -5.605  -51.643 1.00 50.09 ? 229 ILE D C   1 
ATOM   7224 O O   . ILE D 1 227 ? -32.310 -5.599  -50.547 1.00 54.41 ? 229 ILE D O   1 
ATOM   7225 C CB  . ILE D 1 227 ? -35.203 -5.887  -52.608 1.00 54.43 ? 229 ILE D CB  1 
ATOM   7226 C CG1 . ILE D 1 227 ? -35.745 -6.993  -51.696 1.00 55.41 ? 229 ILE D CG1 1 
ATOM   7227 C CG2 . ILE D 1 227 ? -34.491 -6.579  -53.766 1.00 49.06 ? 229 ILE D CG2 1 
ATOM   7228 C CD1 . ILE D 1 227 ? -37.224 -7.303  -51.891 1.00 54.54 ? 229 ILE D CD1 1 
HETATM 7229 O O   . HOH E 2 .   ? -52.973 7.769   -6.573  1.00 36.27 ? 601 HOH A O   1 
HETATM 7230 O O   . HOH E 2 .   ? -37.278 15.533  -29.825 1.00 42.23 ? 602 HOH A O   1 
HETATM 7231 O O   . HOH E 2 .   ? -32.341 19.769  -23.990 1.00 44.24 ? 603 HOH A O   1 
HETATM 7232 O O   . HOH E 2 .   ? -55.567 17.551  0.122   1.00 36.44 ? 604 HOH A O   1 
HETATM 7233 O O   . HOH E 2 .   ? -64.657 23.338  -21.409 1.00 28.87 ? 605 HOH A O   1 
HETATM 7234 O O   . HOH E 2 .   ? -59.789 34.415  -13.281 1.00 38.53 ? 606 HOH A O   1 
HETATM 7235 O O   . HOH E 2 .   ? -43.445 45.637  -2.679  1.00 36.15 ? 607 HOH A O   1 
HETATM 7236 O O   . HOH E 2 .   ? -31.386 30.625  -27.883 1.00 46.46 ? 608 HOH A O   1 
HETATM 7237 O O   . HOH E 2 .   ? -32.895 16.907  -20.619 1.00 24.80 ? 609 HOH A O   1 
HETATM 7238 O O   . HOH E 2 .   ? -42.556 5.378   -19.353 1.00 27.44 ? 610 HOH A O   1 
HETATM 7239 O O   . HOH E 2 .   ? -37.377 11.296  -24.525 1.00 42.24 ? 611 HOH A O   1 
HETATM 7240 O O   . HOH E 2 .   ? -41.957 33.852  4.536   1.00 47.31 ? 612 HOH A O   1 
HETATM 7241 O O   . HOH E 2 .   ? -43.933 33.438  -17.430 1.00 24.72 ? 613 HOH A O   1 
HETATM 7242 O O   . HOH E 2 .   ? -59.249 7.921   -15.138 1.00 46.13 ? 614 HOH A O   1 
HETATM 7243 O O   . HOH E 2 .   ? -27.391 24.202  -9.982  1.00 35.99 ? 615 HOH A O   1 
HETATM 7244 O O   . HOH E 2 .   ? -47.345 24.885  -12.556 1.00 11.34 ? 616 HOH A O   1 
HETATM 7245 O O   . HOH E 2 .   ? -39.150 32.850  -11.915 1.00 18.76 ? 617 HOH A O   1 
HETATM 7246 O O   . HOH E 2 .   ? -52.420 10.148  -14.756 1.00 25.64 ? 618 HOH A O   1 
HETATM 7247 O O   . HOH E 2 .   ? -41.185 26.561  -7.894  1.00 17.84 ? 619 HOH A O   1 
HETATM 7248 O O   . HOH E 2 .   ? -50.141 13.438  -21.688 1.00 28.19 ? 620 HOH A O   1 
HETATM 7249 O O   . HOH E 2 .   ? -57.955 26.451  -19.695 1.00 22.84 ? 621 HOH A O   1 
HETATM 7250 O O   . HOH E 2 .   ? -40.700 29.974  4.359   1.00 33.53 ? 622 HOH A O   1 
HETATM 7251 O O   . HOH E 2 .   ? -39.323 42.320  -9.213  1.00 30.07 ? 623 HOH A O   1 
HETATM 7252 O O   . HOH E 2 .   ? -47.617 16.523  -32.763 1.00 30.37 ? 624 HOH A O   1 
HETATM 7253 O O   . HOH E 2 .   ? -50.740 39.970  -24.958 1.00 30.71 ? 625 HOH A O   1 
HETATM 7254 O O   . HOH E 2 .   ? -26.654 34.447  -22.386 1.00 25.63 ? 626 HOH A O   1 
HETATM 7255 O O   . HOH E 2 .   ? -35.524 14.957  -18.561 1.00 15.13 ? 627 HOH A O   1 
HETATM 7256 O O   . HOH E 2 .   ? -29.956 43.222  -0.992  1.00 43.10 ? 628 HOH A O   1 
HETATM 7257 O O   . HOH E 2 .   ? -44.634 35.634  -16.805 1.00 19.78 ? 629 HOH A O   1 
HETATM 7258 O O   . HOH E 2 .   ? -25.865 29.947  -7.699  1.00 29.69 ? 630 HOH A O   1 
HETATM 7259 O O   . HOH E 2 .   ? -48.355 37.150  -15.141 1.00 20.62 ? 631 HOH A O   1 
HETATM 7260 O O   . HOH E 2 .   ? -39.563 11.623  -9.367  1.00 36.01 ? 632 HOH A O   1 
HETATM 7261 O O   . HOH E 2 .   ? -57.079 23.505  -19.133 1.00 22.85 ? 633 HOH A O   1 
HETATM 7262 O O   . HOH E 2 .   ? -60.322 17.046  -9.883  1.00 25.58 ? 634 HOH A O   1 
HETATM 7263 O O   . HOH E 2 .   ? -44.252 24.740  -0.919  1.00 24.69 ? 635 HOH A O   1 
HETATM 7264 O O   . HOH E 2 .   ? -55.941 17.005  -19.620 1.00 24.92 ? 636 HOH A O   1 
HETATM 7265 O O   . HOH E 2 .   ? -22.207 32.305  -15.951 1.00 37.78 ? 637 HOH A O   1 
HETATM 7266 O O   . HOH E 2 .   ? -34.783 45.097  -15.656 1.00 33.45 ? 638 HOH A O   1 
HETATM 7267 O O   . HOH E 2 .   ? -36.296 42.350  -29.349 1.00 39.76 ? 639 HOH A O   1 
HETATM 7268 O O   . HOH E 2 .   ? -47.067 27.780  -28.833 1.00 18.07 ? 640 HOH A O   1 
HETATM 7269 O O   . HOH E 2 .   ? -33.013 38.475  -22.589 1.00 19.41 ? 641 HOH A O   1 
HETATM 7270 O O   . HOH E 2 .   ? -33.756 47.119  -3.183  1.00 40.30 ? 642 HOH A O   1 
HETATM 7271 O O   . HOH E 2 .   ? -30.827 26.221  -11.928 1.00 16.94 ? 643 HOH A O   1 
HETATM 7272 O O   . HOH E 2 .   ? -47.510 18.346  -2.283  1.00 21.88 ? 644 HOH A O   1 
HETATM 7273 O O   . HOH E 2 .   ? -56.707 14.314  -10.324 1.00 21.52 ? 645 HOH A O   1 
HETATM 7274 O O   . HOH E 2 .   ? -48.506 33.883  -26.440 1.00 16.33 ? 646 HOH A O   1 
HETATM 7275 O O   . HOH E 2 .   ? -43.543 8.499   -4.168  1.00 30.20 ? 647 HOH A O   1 
HETATM 7276 O O   . HOH E 2 .   ? -37.450 40.158  -14.657 1.00 19.35 ? 648 HOH A O   1 
HETATM 7277 O O   . HOH E 2 .   ? -60.063 10.046  -17.114 1.00 39.78 ? 649 HOH A O   1 
HETATM 7278 O O   . HOH E 2 .   ? -48.347 8.608   -17.507 1.00 28.59 ? 650 HOH A O   1 
HETATM 7279 O O   . HOH E 2 .   ? -49.840 38.509  -4.944  1.00 23.53 ? 651 HOH A O   1 
HETATM 7280 O O   . HOH E 2 .   ? -64.506 18.923  -11.901 1.00 31.67 ? 652 HOH A O   1 
HETATM 7281 O O   . HOH E 2 .   ? -56.391 31.936  -14.911 1.00 18.53 ? 653 HOH A O   1 
HETATM 7282 O O   . HOH E 2 .   ? -53.893 33.031  -3.749  1.00 33.71 ? 654 HOH A O   1 
HETATM 7283 O O   . HOH E 2 .   ? -50.480 15.005  -23.917 1.00 26.71 ? 655 HOH A O   1 
HETATM 7284 O O   . HOH E 2 .   ? -65.241 19.914  -24.545 1.00 37.17 ? 656 HOH A O   1 
HETATM 7285 O O   . HOH E 2 .   ? -43.884 31.634  3.669   1.00 35.70 ? 657 HOH A O   1 
HETATM 7286 O O   . HOH E 2 .   ? -27.433 26.407  -24.071 1.00 29.18 ? 658 HOH A O   1 
HETATM 7287 O O   . HOH E 2 .   ? -46.867 34.516  -1.359  1.00 22.73 ? 659 HOH A O   1 
HETATM 7288 O O   . HOH E 2 .   ? -37.219 19.793  -30.717 1.00 39.94 ? 660 HOH A O   1 
HETATM 7289 O O   . HOH E 2 .   ? -30.579 45.352  -25.819 1.00 39.53 ? 661 HOH A O   1 
HETATM 7290 O O   . HOH E 2 .   ? -51.774 17.498  -24.671 1.00 24.48 ? 662 HOH A O   1 
HETATM 7291 O O   . HOH E 2 .   ? -35.825 52.907  -13.066 1.00 47.81 ? 663 HOH A O   1 
HETATM 7292 O O   . HOH E 2 .   ? -38.747 10.513  -7.133  1.00 38.29 ? 664 HOH A O   1 
HETATM 7293 O O   . HOH E 2 .   ? -55.431 14.053  3.019   1.00 43.98 ? 665 HOH A O   1 
HETATM 7294 O O   . HOH E 2 .   ? -51.415 38.195  -7.918  1.00 21.55 ? 666 HOH A O   1 
HETATM 7295 O O   . HOH E 2 .   ? -31.610 27.145  -26.564 1.00 28.13 ? 667 HOH A O   1 
HETATM 7296 O O   . HOH E 2 .   ? -54.617 33.587  -21.568 1.00 24.49 ? 668 HOH A O   1 
HETATM 7297 O O   . HOH E 2 .   ? -35.376 16.882  -15.618 1.00 18.93 ? 669 HOH A O   1 
HETATM 7298 O O   . HOH E 2 .   ? -25.731 40.469  -22.355 1.00 32.72 ? 670 HOH A O   1 
HETATM 7299 O O   . HOH E 2 .   ? -26.872 42.178  -10.066 1.00 32.20 ? 671 HOH A O   1 
HETATM 7300 O O   . HOH E 2 .   ? -27.345 37.220  -25.114 1.00 31.15 ? 672 HOH A O   1 
HETATM 7301 O O   . HOH E 2 .   ? -67.291 19.340  -15.680 1.00 39.66 ? 673 HOH A O   1 
HETATM 7302 O O   . HOH E 2 .   ? -57.343 34.562  -18.572 1.00 23.54 ? 674 HOH A O   1 
HETATM 7303 O O   . HOH E 2 .   ? -49.883 26.379  -14.782 1.00 16.36 ? 675 HOH A O   1 
HETATM 7304 O O   . HOH E 2 .   ? -43.805 9.620   -17.521 1.00 26.74 ? 676 HOH A O   1 
HETATM 7305 O O   . HOH E 2 .   ? -32.083 43.620  -19.348 1.00 37.66 ? 677 HOH A O   1 
HETATM 7306 O O   . HOH E 2 .   ? -55.550 25.426  -18.757 1.00 21.99 ? 678 HOH A O   1 
HETATM 7307 O O   . HOH E 2 .   ? -24.672 40.291  -10.099 1.00 32.76 ? 679 HOH A O   1 
HETATM 7308 O O   . HOH E 2 .   ? -57.256 15.528  -22.047 1.00 36.34 ? 680 HOH A O   1 
HETATM 7309 O O   . HOH E 2 .   ? -45.508 8.246   -13.990 1.00 33.28 ? 681 HOH A O   1 
HETATM 7310 O O   . HOH E 2 .   ? -43.136 11.094  -24.377 1.00 23.19 ? 682 HOH A O   1 
HETATM 7311 O O   . HOH E 2 .   ? -48.269 15.538  -26.676 1.00 19.15 ? 683 HOH A O   1 
HETATM 7312 O O   . HOH E 2 .   ? -44.646 26.360  -9.303  1.00 14.13 ? 684 HOH A O   1 
HETATM 7313 O O   . HOH E 2 .   ? -55.310 38.691  -14.732 1.00 26.53 ? 685 HOH A O   1 
HETATM 7314 O O   . HOH E 2 .   ? -54.855 28.058  -17.509 1.00 18.29 ? 686 HOH A O   1 
HETATM 7315 O O   . HOH E 2 .   ? -66.641 25.823  -13.076 1.00 25.90 ? 687 HOH A O   1 
HETATM 7316 O O   . HOH E 2 .   ? -48.215 36.652  -1.708  1.00 21.72 ? 688 HOH A O   1 
HETATM 7317 O O   . HOH E 2 .   ? -57.879 20.098  -25.485 1.00 31.62 ? 689 HOH A O   1 
HETATM 7318 O O   . HOH E 2 .   ? -26.610 39.143  -7.761  1.00 33.88 ? 690 HOH A O   1 
HETATM 7319 O O   . HOH E 2 .   ? -29.468 23.899  -11.672 1.00 26.86 ? 691 HOH A O   1 
HETATM 7320 O O   . HOH E 2 .   ? -53.041 32.414  -28.273 1.00 24.63 ? 692 HOH A O   1 
HETATM 7321 O O   . HOH E 2 .   ? -58.285 15.077  -2.731  1.00 32.99 ? 693 HOH A O   1 
HETATM 7322 O O   . HOH E 2 .   ? -32.054 17.535  -11.876 1.00 30.34 ? 694 HOH A O   1 
HETATM 7323 O O   . HOH E 2 .   ? -26.097 27.771  -7.279  1.00 33.78 ? 695 HOH A O   1 
HETATM 7324 O O   . HOH E 2 .   ? -28.404 35.928  -5.789  1.00 24.38 ? 696 HOH A O   1 
HETATM 7325 O O   . HOH E 2 .   ? -52.999 27.910  -26.026 1.00 23.90 ? 697 HOH A O   1 
HETATM 7326 O O   . HOH E 2 .   ? -63.048 31.806  -8.509  1.00 47.52 ? 698 HOH A O   1 
HETATM 7327 O O   . HOH E 2 .   ? -37.841 30.953  -1.737  1.00 26.53 ? 699 HOH A O   1 
HETATM 7328 O O   . HOH E 2 .   ? -38.782 28.558  -11.255 1.00 12.24 ? 700 HOH A O   1 
HETATM 7329 O O   . HOH E 2 .   ? -27.960 38.892  -23.113 1.00 29.42 ? 701 HOH A O   1 
HETATM 7330 O O   . HOH E 2 .   ? -56.681 23.102  -27.840 1.00 37.61 ? 702 HOH A O   1 
HETATM 7331 O O   . HOH E 2 .   ? -46.088 24.817  -32.704 1.00 32.58 ? 703 HOH A O   1 
HETATM 7332 O O   . HOH E 2 .   ? -61.965 16.892  -8.261  1.00 41.86 ? 704 HOH A O   1 
HETATM 7333 O O   . HOH E 2 .   ? -41.731 32.997  -16.700 1.00 18.08 ? 705 HOH A O   1 
HETATM 7334 O O   . HOH E 2 .   ? -34.793 22.133  -6.086  1.00 27.50 ? 706 HOH A O   1 
HETATM 7335 O O   . HOH E 2 .   ? -55.686 17.699  -22.898 1.00 36.11 ? 707 HOH A O   1 
HETATM 7336 O O   . HOH E 2 .   ? -51.433 25.320  -12.563 1.00 15.49 ? 708 HOH A O   1 
HETATM 7337 O O   . HOH E 2 .   ? -54.745 29.270  -24.718 1.00 29.55 ? 709 HOH A O   1 
HETATM 7338 O O   . HOH E 2 .   ? -54.331 19.599  -0.948  1.00 28.93 ? 710 HOH A O   1 
HETATM 7339 O O   . HOH E 2 .   ? -55.870 21.318  -2.987  1.00 21.75 ? 711 HOH A O   1 
HETATM 7340 O O   . HOH E 2 .   ? -26.163 36.319  -20.818 1.00 28.51 ? 712 HOH A O   1 
HETATM 7341 O O   . HOH E 2 .   ? -28.794 37.980  -0.572  1.00 44.31 ? 713 HOH A O   1 
HETATM 7342 O O   . HOH E 2 .   ? -45.637 36.001  -14.041 1.00 18.48 ? 714 HOH A O   1 
HETATM 7343 O O   . HOH E 2 .   ? -37.389 19.970  -25.562 1.00 38.45 ? 715 HOH A O   1 
HETATM 7344 O O   . HOH E 2 .   ? -45.782 6.148   -20.546 1.00 33.69 ? 716 HOH A O   1 
HETATM 7345 O O   . HOH E 2 .   ? -42.065 24.368  -1.970  1.00 23.01 ? 717 HOH A O   1 
HETATM 7346 O O   . HOH E 2 .   ? -59.345 11.814  -20.337 1.00 37.21 ? 718 HOH A O   1 
HETATM 7347 O O   . HOH E 2 .   ? -53.993 25.822  -27.231 1.00 37.04 ? 719 HOH A O   1 
HETATM 7348 O O   . HOH E 2 .   ? -24.210 35.145  -19.222 1.00 39.80 ? 720 HOH A O   1 
HETATM 7349 O O   . HOH E 2 .   ? -25.276 25.238  -8.879  1.00 32.21 ? 721 HOH A O   1 
HETATM 7350 O O   . HOH E 2 .   ? -40.939 27.454  -10.593 1.00 13.95 ? 722 HOH A O   1 
HETATM 7351 O O   . HOH E 2 .   ? -57.887 25.630  -4.765  1.00 29.55 ? 723 HOH A O   1 
HETATM 7352 O O   . HOH E 2 .   ? -60.252 21.939  -2.012  1.00 32.29 ? 724 HOH A O   1 
HETATM 7353 O O   . HOH E 2 .   ? -63.026 14.621  -19.789 1.00 37.68 ? 725 HOH A O   1 
HETATM 7354 O O   . HOH E 2 .   ? -21.962 47.295  -19.810 1.00 41.99 ? 726 HOH A O   1 
HETATM 7355 O O   . HOH E 2 .   ? -51.715 37.891  -17.366 1.00 20.58 ? 727 HOH A O   1 
HETATM 7356 O O   . HOH E 2 .   ? -38.147 8.277   -5.056  1.00 32.54 ? 728 HOH A O   1 
HETATM 7357 O O   . HOH E 2 .   ? -30.885 25.846  -24.308 1.00 28.90 ? 729 HOH A O   1 
HETATM 7358 O O   . HOH E 2 .   ? -61.754 30.348  -20.149 1.00 26.30 ? 730 HOH A O   1 
HETATM 7359 O O   . HOH E 2 .   ? -29.775 34.061  0.669   1.00 37.45 ? 731 HOH A O   1 
HETATM 7360 O O   . HOH E 2 .   ? -55.882 9.515   -17.604 1.00 35.22 ? 732 HOH A O   1 
HETATM 7361 O O   . HOH E 2 .   ? -57.168 32.245  -23.484 1.00 25.79 ? 733 HOH A O   1 
HETATM 7362 O O   . HOH E 2 .   ? -63.575 31.008  -11.183 1.00 45.73 ? 734 HOH A O   1 
HETATM 7363 O O   . HOH E 2 .   ? -42.903 46.621  -25.821 1.00 28.08 ? 735 HOH A O   1 
HETATM 7364 O O   . HOH E 2 .   ? -44.202 18.376  -41.185 1.00 48.12 ? 736 HOH A O   1 
HETATM 7365 O O   . HOH E 2 .   ? -36.466 43.617  -19.152 1.00 28.26 ? 737 HOH A O   1 
HETATM 7366 O O   . HOH E 2 .   ? -48.507 39.970  -22.030 1.00 23.47 ? 738 HOH A O   1 
HETATM 7367 O O   . HOH E 2 .   ? -29.495 23.497  -9.101  1.00 33.56 ? 739 HOH A O   1 
HETATM 7368 O O   . HOH E 2 .   ? -63.191 18.761  -1.645  1.00 37.66 ? 740 HOH A O   1 
HETATM 7369 O O   . HOH E 2 .   ? -43.576 6.018   -11.764 1.00 17.96 ? 741 HOH A O   1 
HETATM 7370 O O   . HOH E 2 .   ? -39.824 15.194  -6.566  1.00 42.56 ? 742 HOH A O   1 
HETATM 7371 O O   . HOH E 2 .   ? -50.555 23.225  -32.748 1.00 42.61 ? 743 HOH A O   1 
HETATM 7372 O O   . HOH E 2 .   ? -54.756 11.016  -21.450 1.00 38.63 ? 744 HOH A O   1 
HETATM 7373 O O   . HOH E 2 .   ? -65.987 23.831  -6.546  1.00 45.33 ? 745 HOH A O   1 
HETATM 7374 O O   . HOH E 2 .   ? -47.944 7.399   -14.580 1.00 35.45 ? 746 HOH A O   1 
HETATM 7375 O O   . HOH E 2 .   ? -64.733 16.178  -15.379 1.00 24.51 ? 747 HOH A O   1 
HETATM 7376 O O   . HOH E 2 .   ? -34.262 18.640  -10.265 1.00 24.17 ? 748 HOH A O   1 
HETATM 7377 O O   . HOH E 2 .   ? -52.362 17.816  -21.599 1.00 14.50 ? 749 HOH A O   1 
HETATM 7378 O O   . HOH E 2 .   ? -37.804 34.071  -27.832 1.00 31.78 ? 750 HOH A O   1 
HETATM 7379 O O   . HOH E 2 .   ? -52.047 10.513  -2.291  1.00 40.57 ? 751 HOH A O   1 
HETATM 7380 O O   . HOH E 2 .   ? -32.970 25.432  -28.363 1.00 42.02 ? 752 HOH A O   1 
HETATM 7381 O O   . HOH E 2 .   ? -53.908 4.352   -11.661 1.00 44.88 ? 753 HOH A O   1 
HETATM 7382 O O   . HOH E 2 .   ? -26.782 38.391  -5.633  1.00 41.00 ? 754 HOH A O   1 
HETATM 7383 O O   . HOH E 2 .   ? -22.335 31.065  -14.091 1.00 39.68 ? 755 HOH A O   1 
HETATM 7384 O O   . HOH E 2 .   ? -33.232 22.378  -7.783  1.00 31.61 ? 756 HOH A O   1 
HETATM 7385 O O   . HOH E 2 .   ? -61.566 30.915  -17.143 1.00 25.41 ? 757 HOH A O   1 
HETATM 7386 O O   . HOH E 2 .   ? -70.140 22.864  -15.951 1.00 39.37 ? 758 HOH A O   1 
HETATM 7387 O O   . HOH E 2 .   ? -37.756 25.849  -28.980 1.00 31.05 ? 759 HOH A O   1 
HETATM 7388 O O   . HOH E 2 .   ? -50.533 8.647   -3.706  1.00 34.01 ? 760 HOH A O   1 
HETATM 7389 O O   . HOH E 2 .   ? -63.047 22.279  -8.829  1.00 30.33 ? 761 HOH A O   1 
HETATM 7390 O O   . HOH E 2 .   ? -35.420 19.026  -24.691 1.00 36.43 ? 762 HOH A O   1 
HETATM 7391 O O   . HOH E 2 .   ? -46.954 4.398   -13.148 1.00 20.54 ? 763 HOH A O   1 
HETATM 7392 O O   . HOH E 2 .   ? -62.227 22.780  -1.106  1.00 44.78 ? 764 HOH A O   1 
HETATM 7393 O O   . HOH E 2 .   ? -23.168 34.718  -16.429 1.00 32.68 ? 765 HOH A O   1 
HETATM 7394 O O   . HOH E 2 .   ? -46.881 4.376   -9.581  1.00 48.96 ? 766 HOH A O   1 
HETATM 7395 O O   . HOH E 2 .   ? -19.549 31.409  -20.567 1.00 30.94 ? 767 HOH A O   1 
HETATM 7396 O O   . HOH E 2 .   ? -58.228 34.136  -15.062 1.00 25.91 ? 768 HOH A O   1 
HETATM 7397 O O   . HOH E 2 .   ? -44.338 28.674  -0.930  1.00 32.68 ? 769 HOH A O   1 
HETATM 7398 O O   . HOH E 2 .   ? -45.158 9.319   -25.098 1.00 44.22 ? 770 HOH A O   1 
HETATM 7399 O O   . HOH E 2 .   ? -36.300 35.430  -28.889 1.00 27.51 ? 771 HOH A O   1 
HETATM 7400 O O   . HOH E 2 .   ? -48.268 8.287   -2.928  1.00 40.54 ? 772 HOH A O   1 
HETATM 7401 O O   . HOH E 2 .   ? -54.491 38.788  -17.315 1.00 26.86 ? 773 HOH A O   1 
HETATM 7402 O O   . HOH E 2 .   ? -55.766 34.905  -5.078  1.00 34.62 ? 774 HOH A O   1 
HETATM 7403 O O   . HOH E 2 .   ? -52.443 22.525  -29.893 1.00 28.01 ? 775 HOH A O   1 
HETATM 7404 O O   . HOH E 2 .   ? -46.587 17.366  -40.794 1.00 44.55 ? 776 HOH A O   1 
HETATM 7405 O O   . HOH E 2 .   ? -56.290 46.786  -7.210  1.00 52.27 ? 777 HOH A O   1 
HETATM 7406 O O   . HOH E 2 .   ? -46.540 29.185  -31.360 1.00 42.11 ? 778 HOH A O   1 
HETATM 7407 O O   . HOH E 2 .   ? -25.683 34.916  -24.720 1.00 38.57 ? 779 HOH A O   1 
HETATM 7408 O O   . HOH E 2 .   ? -58.060 22.788  -1.906  1.00 28.02 ? 780 HOH A O   1 
HETATM 7409 O O   . HOH E 2 .   ? -45.511 30.568  -0.022  1.00 31.08 ? 781 HOH A O   1 
HETATM 7410 O O   . HOH E 2 .   ? -42.359 35.993  -16.676 1.00 35.02 ? 782 HOH A O   1 
HETATM 7411 O O   . HOH E 2 .   ? -40.927 8.976   -24.688 1.00 37.55 ? 783 HOH A O   1 
HETATM 7412 O O   . HOH E 2 .   ? -63.769 26.562  -8.921  1.00 34.77 ? 784 HOH A O   1 
HETATM 7413 O O   . HOH E 2 .   ? -65.970 18.100  -13.501 1.00 41.69 ? 785 HOH A O   1 
HETATM 7414 O O   . HOH E 2 .   ? -45.052 28.884  1.422   1.00 29.43 ? 786 HOH A O   1 
HETATM 7415 O O   . HOH E 2 .   ? -36.696 20.134  -28.291 1.00 40.67 ? 787 HOH A O   1 
HETATM 7416 O O   . HOH E 2 .   ? -30.232 28.387  -28.087 1.00 39.20 ? 788 HOH A O   1 
HETATM 7417 O O   . HOH E 2 .   ? -40.345 18.515  -3.025  1.00 37.80 ? 789 HOH A O   1 
HETATM 7418 O O   . HOH E 2 .   ? -53.388 15.942  -20.824 1.00 29.24 ? 790 HOH A O   1 
HETATM 7419 O O   . HOH E 2 .   ? -44.300 25.201  2.463   1.00 34.79 ? 791 HOH A O   1 
HETATM 7420 O O   . HOH E 2 .   ? -69.265 24.574  -13.234 1.00 44.76 ? 792 HOH A O   1 
HETATM 7421 O O   . HOH E 2 .   ? -54.242 39.431  -7.987  1.00 44.40 ? 793 HOH A O   1 
HETATM 7422 O O   . HOH E 2 .   ? -54.380 13.725  -22.411 1.00 39.72 ? 794 HOH A O   1 
HETATM 7423 O O   . HOH E 2 .   ? -44.182 28.846  -30.855 1.00 35.83 ? 795 HOH A O   1 
HETATM 7424 O O   . HOH E 2 .   ? -53.745 20.493  -29.613 1.00 39.49 ? 796 HOH A O   1 
HETATM 7425 O O   . HOH F 2 .   ? -33.456 13.581  -23.337 1.00 35.87 ? 301 HOH B O   1 
HETATM 7426 O O   . HOH F 2 .   ? -36.150 -13.279 -12.295 1.00 48.25 ? 302 HOH B O   1 
HETATM 7427 O O   . HOH F 2 .   ? -19.593 18.049  -35.808 1.00 44.61 ? 303 HOH B O   1 
HETATM 7428 O O   . HOH F 2 .   ? -15.882 20.292  -23.868 1.00 34.55 ? 304 HOH B O   1 
HETATM 7429 O O   . HOH F 2 .   ? -27.145 22.174  -13.625 1.00 22.93 ? 305 HOH B O   1 
HETATM 7430 O O   . HOH F 2 .   ? -38.277 5.720   -5.819  1.00 27.46 ? 306 HOH B O   1 
HETATM 7431 O O   . HOH F 2 .   ? -41.533 -0.992  -16.480 1.00 29.67 ? 307 HOH B O   1 
HETATM 7432 O O   . HOH F 2 .   ? -43.539 2.074   -21.975 1.00 41.46 ? 308 HOH B O   1 
HETATM 7433 O O   . HOH F 2 .   ? -22.738 28.458  -21.896 1.00 27.46 ? 309 HOH B O   1 
HETATM 7434 O O   . HOH F 2 .   ? -30.246 -4.915  -27.255 1.00 34.67 ? 310 HOH B O   1 
HETATM 7435 O O   . HOH F 2 .   ? -1.976  28.323  -19.319 1.00 36.13 ? 311 HOH B O   1 
HETATM 7436 O O   . HOH F 2 .   ? -35.914 2.006   -25.762 1.00 35.27 ? 312 HOH B O   1 
HETATM 7437 O O   . HOH F 2 .   ? -7.345  19.092  -3.414  1.00 24.41 ? 313 HOH B O   1 
HETATM 7438 O O   . HOH F 2 .   ? -42.042 1.691   1.821   1.00 51.62 ? 314 HOH B O   1 
HETATM 7439 O O   . HOH F 2 .   ? -25.433 2.447   -10.518 1.00 17.24 ? 315 HOH B O   1 
HETATM 7440 O O   . HOH F 2 .   ? -7.722  0.977   -21.980 1.00 26.48 ? 316 HOH B O   1 
HETATM 7441 O O   . HOH F 2 .   ? -15.698 18.370  -25.908 1.00 30.83 ? 317 HOH B O   1 
HETATM 7442 O O   . HOH F 2 .   ? -21.327 -5.416  5.932   1.00 38.51 ? 318 HOH B O   1 
HETATM 7443 O O   . HOH F 2 .   ? -29.884 19.359  -19.222 1.00 17.03 ? 319 HOH B O   1 
HETATM 7444 O O   . HOH F 2 .   ? -20.291 27.325  -6.460  1.00 29.77 ? 320 HOH B O   1 
HETATM 7445 O O   . HOH F 2 .   ? -40.525 1.156   0.230   1.00 41.57 ? 321 HOH B O   1 
HETATM 7446 O O   . HOH F 2 .   ? -28.168 -12.789 -20.409 1.00 31.81 ? 322 HOH B O   1 
HETATM 7447 O O   . HOH F 2 .   ? -4.204  18.573  -13.016 1.00 24.64 ? 323 HOH B O   1 
HETATM 7448 O O   . HOH F 2 .   ? -41.244 -7.101  -8.423  1.00 40.10 ? 324 HOH B O   1 
HETATM 7449 O O   . HOH F 2 .   ? -26.361 11.527  -36.975 1.00 38.89 ? 325 HOH B O   1 
HETATM 7450 O O   . HOH F 2 .   ? -2.017  12.430  -26.591 1.00 22.72 ? 326 HOH B O   1 
HETATM 7451 O O   . HOH F 2 .   ? -12.415 -2.687  -23.296 1.00 27.23 ? 327 HOH B O   1 
HETATM 7452 O O   . HOH F 2 .   ? -12.721 24.518  -17.799 1.00 21.29 ? 328 HOH B O   1 
HETATM 7453 O O   . HOH F 2 .   ? -0.294  17.979  -5.730  1.00 40.25 ? 329 HOH B O   1 
HETATM 7454 O O   . HOH F 2 .   ? -31.798 -7.244  2.807   1.00 43.46 ? 330 HOH B O   1 
HETATM 7455 O O   . HOH F 2 .   ? -17.480 10.382  -13.181 1.00 11.31 ? 331 HOH B O   1 
HETATM 7456 O O   . HOH F 2 .   ? -12.262 0.995   -23.736 1.00 27.67 ? 332 HOH B O   1 
HETATM 7457 O O   . HOH F 2 .   ? -19.194 4.941   -28.790 1.00 17.43 ? 333 HOH B O   1 
HETATM 7458 O O   . HOH F 2 .   ? -12.248 7.438   -28.165 1.00 27.19 ? 334 HOH B O   1 
HETATM 7459 O O   . HOH F 2 .   ? -38.609 -3.728  -21.684 1.00 34.23 ? 335 HOH B O   1 
HETATM 7460 O O   . HOH F 2 .   ? -16.530 -2.097  -13.889 1.00 14.94 ? 336 HOH B O   1 
HETATM 7461 O O   . HOH F 2 .   ? -1.611  9.421   -22.552 1.00 22.90 ? 337 HOH B O   1 
HETATM 7462 O O   . HOH F 2 .   ? -28.642 22.004  -26.039 1.00 40.26 ? 338 HOH B O   1 
HETATM 7463 O O   . HOH F 2 .   ? -19.656 15.832  -34.276 1.00 29.73 ? 339 HOH B O   1 
HETATM 7464 O O   . HOH F 2 .   ? -18.942 -7.109  2.546   1.00 32.80 ? 340 HOH B O   1 
HETATM 7465 O O   . HOH F 2 .   ? -29.838 17.819  -16.062 1.00 16.73 ? 341 HOH B O   1 
HETATM 7466 O O   . HOH F 2 .   ? -33.804 8.966   -10.605 1.00 20.28 ? 342 HOH B O   1 
HETATM 7467 O O   . HOH F 2 .   ? -20.530 2.067   3.110   1.00 42.96 ? 343 HOH B O   1 
HETATM 7468 O O   . HOH F 2 .   ? -14.280 -2.153  -3.727  1.00 22.18 ? 344 HOH B O   1 
HETATM 7469 O O   . HOH F 2 .   ? -20.207 30.553  -10.057 1.00 33.40 ? 345 HOH B O   1 
HETATM 7470 O O   . HOH F 2 .   ? -7.926  20.997  -13.429 1.00 17.72 ? 346 HOH B O   1 
HETATM 7471 O O   . HOH F 2 .   ? -5.803  20.681  -5.887  1.00 30.16 ? 347 HOH B O   1 
HETATM 7472 O O   . HOH F 2 .   ? -23.226 9.229   -7.743  1.00 12.89 ? 348 HOH B O   1 
HETATM 7473 O O   . HOH F 2 .   ? -30.184 3.409   -27.945 1.00 28.77 ? 349 HOH B O   1 
HETATM 7474 O O   . HOH F 2 .   ? -15.098 8.362   -15.394 1.00 12.86 ? 350 HOH B O   1 
HETATM 7475 O O   . HOH F 2 .   ? -25.320 -6.606  -6.849  1.00 28.11 ? 351 HOH B O   1 
HETATM 7476 O O   . HOH F 2 .   ? -31.451 5.403   0.743   1.00 34.74 ? 352 HOH B O   1 
HETATM 7477 O O   . HOH F 2 .   ? -5.863  20.166  -25.594 1.00 41.07 ? 353 HOH B O   1 
HETATM 7478 O O   . HOH F 2 .   ? -20.805 7.307   -32.633 1.00 31.74 ? 354 HOH B O   1 
HETATM 7479 O O   . HOH F 2 .   ? -4.805  17.739  -4.897  1.00 36.09 ? 355 HOH B O   1 
HETATM 7480 O O   . HOH F 2 .   ? -10.189 8.636   -19.828 1.00 18.48 ? 356 HOH B O   1 
HETATM 7481 O O   . HOH F 2 .   ? -39.718 4.607   -8.729  1.00 24.33 ? 357 HOH B O   1 
HETATM 7482 O O   . HOH F 2 .   ? -6.322  10.128  -7.315  1.00 30.01 ? 358 HOH B O   1 
HETATM 7483 O O   . HOH F 2 .   ? -27.255 -5.146  -11.840 1.00 19.27 ? 359 HOH B O   1 
HETATM 7484 O O   . HOH F 2 .   ? -29.535 -10.334 1.222   1.00 50.42 ? 360 HOH B O   1 
HETATM 7485 O O   . HOH F 2 .   ? 1.727   14.685  -20.844 1.00 27.65 ? 361 HOH B O   1 
HETATM 7486 O O   . HOH F 2 .   ? -19.859 26.286  -17.316 1.00 32.82 ? 362 HOH B O   1 
HETATM 7487 O O   . HOH F 2 .   ? -2.977  16.288  -11.979 1.00 33.68 ? 363 HOH B O   1 
HETATM 7488 O O   . HOH F 2 .   ? -14.545 15.815  -26.547 1.00 20.40 ? 364 HOH B O   1 
HETATM 7489 O O   . HOH F 2 .   ? -8.639  2.762   -15.502 1.00 16.40 ? 365 HOH B O   1 
HETATM 7490 O O   . HOH F 2 .   ? -21.796 24.891  -19.333 1.00 32.57 ? 366 HOH B O   1 
HETATM 7491 O O   . HOH F 2 .   ? -42.427 2.435   -12.698 1.00 34.81 ? 367 HOH B O   1 
HETATM 7492 O O   . HOH F 2 .   ? -8.062  -0.680  -18.717 1.00 24.43 ? 368 HOH B O   1 
HETATM 7493 O O   . HOH F 2 .   ? -9.738  16.886  -22.119 1.00 14.68 ? 369 HOH B O   1 
HETATM 7494 O O   . HOH F 2 .   ? -18.041 23.979  -6.810  1.00 23.46 ? 370 HOH B O   1 
HETATM 7495 O O   . HOH F 2 .   ? -18.182 17.397  -28.412 1.00 17.50 ? 371 HOH B O   1 
HETATM 7496 O O   . HOH F 2 .   ? -7.007  14.711  -27.589 1.00 40.72 ? 372 HOH B O   1 
HETATM 7497 O O   . HOH F 2 .   ? -3.851  26.174  -12.609 1.00 39.80 ? 373 HOH B O   1 
HETATM 7498 O O   . HOH F 2 .   ? -38.983 -0.586  -19.564 1.00 23.15 ? 374 HOH B O   1 
HETATM 7499 O O   . HOH F 2 .   ? -10.158 6.236   -18.312 1.00 16.62 ? 375 HOH B O   1 
HETATM 7500 O O   . HOH F 2 .   ? -16.429 18.130  -4.029  1.00 16.73 ? 376 HOH B O   1 
HETATM 7501 O O   . HOH F 2 .   ? -1.056  17.568  -21.850 1.00 28.55 ? 377 HOH B O   1 
HETATM 7502 O O   . HOH F 2 .   ? -13.415 9.687   -13.482 1.00 10.83 ? 378 HOH B O   1 
HETATM 7503 O O   . HOH F 2 .   ? -35.261 11.483  -10.594 1.00 26.90 ? 379 HOH B O   1 
HETATM 7504 O O   . HOH F 2 .   ? -8.020  7.225   -20.907 1.00 19.59 ? 380 HOH B O   1 
HETATM 7505 O O   . HOH F 2 .   ? -35.204 6.331   1.424   1.00 32.60 ? 381 HOH B O   1 
HETATM 7506 O O   . HOH F 2 .   ? -19.837 9.154   -9.375  1.00 13.87 ? 382 HOH B O   1 
HETATM 7507 O O   . HOH F 2 .   ? -32.582 -4.461  -19.462 1.00 19.22 ? 383 HOH B O   1 
HETATM 7508 O O   . HOH F 2 .   ? -37.565 -5.041  -19.460 1.00 24.72 ? 384 HOH B O   1 
HETATM 7509 O O   . HOH F 2 .   ? -26.013 6.717   -10.398 1.00 13.60 ? 385 HOH B O   1 
HETATM 7510 O O   . HOH F 2 .   ? -37.450 -5.545  -25.271 1.00 32.14 ? 386 HOH B O   1 
HETATM 7511 O O   . HOH F 2 .   ? -8.523  10.557  -20.709 1.00 17.72 ? 387 HOH B O   1 
HETATM 7512 O O   . HOH F 2 .   ? -24.242 -10.833 1.447   1.00 44.83 ? 388 HOH B O   1 
HETATM 7513 O O   . HOH F 2 .   ? -37.455 -6.484  -6.188  1.00 31.90 ? 389 HOH B O   1 
HETATM 7514 O O   . HOH F 2 .   ? -38.443 -0.860  -24.682 1.00 36.83 ? 390 HOH B O   1 
HETATM 7515 O O   . HOH F 2 .   ? -0.266  15.929  -14.958 1.00 33.13 ? 391 HOH B O   1 
HETATM 7516 O O   . HOH F 2 .   ? -23.046 22.360  -26.207 1.00 22.16 ? 392 HOH B O   1 
HETATM 7517 O O   . HOH F 2 .   ? -41.612 -6.543  -11.623 1.00 36.66 ? 393 HOH B O   1 
HETATM 7518 O O   . HOH F 2 .   ? -38.276 7.345   -22.156 1.00 27.47 ? 394 HOH B O   1 
HETATM 7519 O O   . HOH F 2 .   ? -39.690 -4.743  -6.590  1.00 34.17 ? 395 HOH B O   1 
HETATM 7520 O O   . HOH F 2 .   ? -0.799  18.026  -18.766 1.00 25.69 ? 396 HOH B O   1 
HETATM 7521 O O   . HOH F 2 .   ? -6.432  27.533  -10.039 1.00 25.33 ? 397 HOH B O   1 
HETATM 7522 O O   . HOH F 2 .   ? -20.385 -9.913  -21.508 1.00 21.29 ? 398 HOH B O   1 
HETATM 7523 O O   . HOH F 2 .   ? -28.646 13.195  -25.702 1.00 38.38 ? 399 HOH B O   1 
HETATM 7524 O O   . HOH F 2 .   ? -12.104 25.222  -4.966  1.00 24.29 ? 400 HOH B O   1 
HETATM 7525 O O   . HOH F 2 .   ? -39.912 -6.393  -18.232 1.00 33.10 ? 401 HOH B O   1 
HETATM 7526 O O   . HOH F 2 .   ? -30.066 19.057  -8.592  1.00 26.88 ? 402 HOH B O   1 
HETATM 7527 O O   . HOH F 2 .   ? -19.187 -0.837  -12.791 1.00 16.01 ? 403 HOH B O   1 
HETATM 7528 O O   . HOH F 2 .   ? -35.354 0.241   -2.955  1.00 23.74 ? 404 HOH B O   1 
HETATM 7529 O O   . HOH F 2 .   ? -8.294  12.573  -27.815 1.00 27.45 ? 405 HOH B O   1 
HETATM 7530 O O   . HOH F 2 .   ? -13.468 -3.296  -16.488 1.00 15.85 ? 406 HOH B O   1 
HETATM 7531 O O   . HOH F 2 .   ? -37.478 -3.189  -4.417  1.00 31.56 ? 407 HOH B O   1 
HETATM 7532 O O   . HOH F 2 .   ? -22.469 32.165  -11.016 1.00 30.64 ? 408 HOH B O   1 
HETATM 7533 O O   . HOH F 2 .   ? -23.596 8.075   -10.200 1.00 12.13 ? 409 HOH B O   1 
HETATM 7534 O O   . HOH F 2 .   ? -18.224 10.414  -35.752 1.00 32.62 ? 410 HOH B O   1 
HETATM 7535 O O   . HOH F 2 .   ? -12.697 -2.357  -6.820  1.00 21.59 ? 411 HOH B O   1 
HETATM 7536 O O   . HOH F 2 .   ? -25.891 -13.928 -19.106 1.00 30.34 ? 412 HOH B O   1 
HETATM 7537 O O   . HOH F 2 .   ? -33.607 9.914   -1.187  1.00 41.85 ? 413 HOH B O   1 
HETATM 7538 O O   . HOH F 2 .   ? -26.679 19.503  -34.247 1.00 32.67 ? 414 HOH B O   1 
HETATM 7539 O O   . HOH F 2 .   ? -2.306  11.160  -11.638 1.00 23.38 ? 415 HOH B O   1 
HETATM 7540 O O   . HOH F 2 .   ? -13.040 26.559  -16.234 1.00 38.31 ? 416 HOH B O   1 
HETATM 7541 O O   . HOH F 2 .   ? -40.778 -9.179  -17.186 1.00 41.01 ? 417 HOH B O   1 
HETATM 7542 O O   . HOH F 2 .   ? -39.249 -2.346  -17.573 1.00 27.25 ? 418 HOH B O   1 
HETATM 7543 O O   . HOH F 2 .   ? -7.979  8.158   -28.664 1.00 29.09 ? 419 HOH B O   1 
HETATM 7544 O O   . HOH F 2 .   ? -16.211 9.418   -33.151 1.00 22.23 ? 420 HOH B O   1 
HETATM 7545 O O   . HOH F 2 .   ? -29.982 -10.212 -12.319 1.00 37.88 ? 421 HOH B O   1 
HETATM 7546 O O   . HOH F 2 .   ? -34.700 6.128   -25.108 1.00 26.82 ? 422 HOH B O   1 
HETATM 7547 O O   . HOH F 2 .   ? -20.355 -0.280  -15.164 1.00 21.96 ? 423 HOH B O   1 
HETATM 7548 O O   . HOH F 2 .   ? -7.994  15.018  -5.320  1.00 17.83 ? 424 HOH B O   1 
HETATM 7549 O O   . HOH F 2 .   ? -16.685 25.781  -20.268 1.00 22.56 ? 425 HOH B O   1 
HETATM 7550 O O   . HOH F 2 .   ? -8.897  -0.203  -8.300  1.00 19.54 ? 426 HOH B O   1 
HETATM 7551 O O   . HOH F 2 .   ? -30.316 23.713  -24.025 1.00 29.49 ? 427 HOH B O   1 
HETATM 7552 O O   . HOH F 2 .   ? -9.768  10.123  -29.370 1.00 38.97 ? 428 HOH B O   1 
HETATM 7553 O O   . HOH F 2 .   ? -7.481  22.545  0.191   1.00 31.26 ? 429 HOH B O   1 
HETATM 7554 O O   . HOH F 2 .   ? -19.966 27.636  -23.152 1.00 31.33 ? 430 HOH B O   1 
HETATM 7555 O O   . HOH F 2 .   ? -33.165 -8.478  -25.147 1.00 35.57 ? 431 HOH B O   1 
HETATM 7556 O O   . HOH F 2 .   ? -30.130 16.778  -10.592 1.00 25.12 ? 432 HOH B O   1 
HETATM 7557 O O   . HOH F 2 .   ? -12.987 5.101   -26.132 1.00 14.99 ? 433 HOH B O   1 
HETATM 7558 O O   . HOH F 2 .   ? -33.899 13.481  -2.517  1.00 44.82 ? 434 HOH B O   1 
HETATM 7559 O O   . HOH F 2 .   ? -14.427 -12.285 -0.678  1.00 45.85 ? 435 HOH B O   1 
HETATM 7560 O O   . HOH F 2 .   ? -12.112 -3.328  -20.311 1.00 37.04 ? 436 HOH B O   1 
HETATM 7561 O O   . HOH F 2 .   ? -34.012 2.865   3.008   1.00 38.43 ? 437 HOH B O   1 
HETATM 7562 O O   . HOH F 2 .   ? -23.212 1.698   -15.575 1.00 17.15 ? 438 HOH B O   1 
HETATM 7563 O O   . HOH F 2 .   ? -8.835  17.094  -3.699  1.00 15.24 ? 439 HOH B O   1 
HETATM 7564 O O   . HOH F 2 .   ? -25.708 5.775   -0.583  1.00 23.61 ? 440 HOH B O   1 
HETATM 7565 O O   . HOH F 2 .   ? -1.171  16.910  -3.984  1.00 42.06 ? 441 HOH B O   1 
HETATM 7566 O O   . HOH F 2 .   ? -21.548 12.338  -2.012  1.00 28.55 ? 442 HOH B O   1 
HETATM 7567 O O   . HOH F 2 .   ? -8.666  26.541  -18.432 1.00 41.65 ? 443 HOH B O   1 
HETATM 7568 O O   . HOH F 2 .   ? -19.017 -16.778 -10.842 1.00 50.14 ? 444 HOH B O   1 
HETATM 7569 O O   . HOH F 2 .   ? -18.487 -12.151 0.217   1.00 38.60 ? 445 HOH B O   1 
HETATM 7570 O O   . HOH F 2 .   ? -11.068 30.801  -13.924 1.00 34.54 ? 446 HOH B O   1 
HETATM 7571 O O   . HOH F 2 .   ? -11.530 14.413  -23.899 1.00 39.76 ? 447 HOH B O   1 
HETATM 7572 O O   . HOH F 2 .   ? -28.626 -0.947  -25.534 1.00 25.09 ? 448 HOH B O   1 
HETATM 7573 O O   . HOH F 2 .   ? -21.265 29.043  -14.649 1.00 19.03 ? 449 HOH B O   1 
HETATM 7574 O O   . HOH F 2 .   ? -1.477  20.114  -15.996 1.00 35.18 ? 450 HOH B O   1 
HETATM 7575 O O   . HOH F 2 .   ? -11.368 3.601   -25.331 1.00 38.50 ? 451 HOH B O   1 
HETATM 7576 O O   . HOH F 2 .   ? -10.524 15.729  -25.390 1.00 26.70 ? 452 HOH B O   1 
HETATM 7577 O O   . HOH F 2 .   ? -35.249 7.709   -22.955 1.00 29.31 ? 453 HOH B O   1 
HETATM 7578 O O   . HOH F 2 .   ? -0.942  12.859  -13.008 1.00 33.61 ? 454 HOH B O   1 
HETATM 7579 O O   . HOH F 2 .   ? -29.189 9.469   1.235   1.00 40.91 ? 455 HOH B O   1 
HETATM 7580 O O   . HOH F 2 .   ? -18.698 2.894   -30.717 1.00 29.82 ? 456 HOH B O   1 
HETATM 7581 O O   . HOH F 2 .   ? -25.798 23.496  -25.759 1.00 37.10 ? 457 HOH B O   1 
HETATM 7582 O O   . HOH F 2 .   ? -33.059 -10.221 -26.885 1.00 48.03 ? 458 HOH B O   1 
HETATM 7583 O O   . HOH F 2 .   ? 2.360   13.537  -17.611 1.00 40.91 ? 459 HOH B O   1 
HETATM 7584 O O   . HOH F 2 .   ? -28.429 -11.192 -17.157 1.00 24.17 ? 460 HOH B O   1 
HETATM 7585 O O   . HOH F 2 .   ? -29.704 13.563  -6.168  1.00 30.91 ? 461 HOH B O   1 
HETATM 7586 O O   . HOH F 2 .   ? -13.827 16.267  -23.843 1.00 14.90 ? 462 HOH B O   1 
HETATM 7587 O O   . HOH F 2 .   ? -14.439 24.812  -20.515 1.00 22.17 ? 463 HOH B O   1 
HETATM 7588 O O   . HOH F 2 .   ? -4.779  -2.707  -11.079 1.00 47.57 ? 464 HOH B O   1 
HETATM 7589 O O   . HOH F 2 .   ? -12.765 25.801  -22.171 1.00 41.66 ? 465 HOH B O   1 
HETATM 7590 O O   . HOH F 2 .   ? -25.289 -18.553 -16.344 1.00 41.79 ? 466 HOH B O   1 
HETATM 7591 O O   . HOH F 2 .   ? -18.823 18.735  -31.039 1.00 34.81 ? 467 HOH B O   1 
HETATM 7592 O O   . HOH F 2 .   ? -24.663 21.201  -8.085  1.00 27.47 ? 468 HOH B O   1 
HETATM 7593 O O   . HOH F 2 .   ? -21.134 24.247  -26.980 1.00 37.76 ? 469 HOH B O   1 
HETATM 7594 O O   . HOH F 2 .   ? -38.817 -5.328  -3.002  1.00 43.68 ? 470 HOH B O   1 
HETATM 7595 O O   . HOH F 2 .   ? -11.692 -2.902  -3.149  1.00 40.95 ? 471 HOH B O   1 
HETATM 7596 O O   . HOH F 2 .   ? -6.270  24.816  -6.151  1.00 26.44 ? 472 HOH B O   1 
HETATM 7597 O O   . HOH F 2 .   ? -36.182 -11.823 -14.769 1.00 41.19 ? 473 HOH B O   1 
HETATM 7598 O O   . HOH F 2 .   ? -30.205 -2.343  -26.912 1.00 29.82 ? 474 HOH B O   1 
HETATM 7599 O O   . HOH F 2 .   ? -18.008 28.789  -6.497  1.00 46.26 ? 475 HOH B O   1 
HETATM 7600 O O   . HOH F 2 .   ? -13.228 27.328  -6.782  1.00 40.55 ? 476 HOH B O   1 
HETATM 7601 O O   . HOH F 2 .   ? -41.534 -14.273 -15.573 1.00 43.65 ? 477 HOH B O   1 
HETATM 7602 O O   . HOH F 2 .   ? -19.869 -17.374 -14.200 1.00 47.61 ? 478 HOH B O   1 
HETATM 7603 O O   . HOH F 2 .   ? -28.234 11.882  2.104   1.00 42.94 ? 479 HOH B O   1 
HETATM 7604 O O   . HOH F 2 .   ? -0.132  9.317   -11.319 1.00 39.94 ? 480 HOH B O   1 
HETATM 7605 O O   . HOH F 2 .   ? -6.750  -1.529  -15.582 1.00 45.22 ? 481 HOH B O   1 
HETATM 7606 O O   . HOH F 2 .   ? -36.521 -1.635  -2.151  1.00 36.25 ? 482 HOH B O   1 
HETATM 7607 O O   . HOH F 2 .   ? -4.647  14.098  -3.961  1.00 19.73 ? 483 HOH B O   1 
HETATM 7608 O O   . HOH F 2 .   ? -40.202 -0.763  -21.683 1.00 35.38 ? 484 HOH B O   1 
HETATM 7609 O O   . HOH F 2 .   ? -41.582 3.167   -7.618  1.00 26.05 ? 485 HOH B O   1 
HETATM 7610 O O   . HOH F 2 .   ? -36.274 4.764   -26.302 1.00 31.70 ? 486 HOH B O   1 
HETATM 7611 O O   . HOH F 2 .   ? -9.717  -4.676  -8.151  1.00 44.91 ? 487 HOH B O   1 
HETATM 7612 O O   . HOH F 2 .   ? -13.990 9.956   -30.989 1.00 24.86 ? 488 HOH B O   1 
HETATM 7613 O O   . HOH F 2 .   ? -30.663 -13.779 -19.945 1.00 38.72 ? 489 HOH B O   1 
HETATM 7614 O O   . HOH F 2 .   ? -21.504 -9.599  11.334  1.00 41.27 ? 490 HOH B O   1 
HETATM 7615 O O   . HOH F 2 .   ? -4.082  14.063  -27.659 1.00 37.92 ? 491 HOH B O   1 
HETATM 7616 O O   . HOH F 2 .   ? -6.351  0.629   -15.680 1.00 32.97 ? 492 HOH B O   1 
HETATM 7617 O O   . HOH F 2 .   ? -5.707  11.217  -28.553 1.00 38.72 ? 493 HOH B O   1 
HETATM 7618 O O   . HOH F 2 .   ? -13.024 15.109  -28.968 1.00 34.12 ? 494 HOH B O   1 
HETATM 7619 O O   . HOH F 2 .   ? -5.149  10.898  -5.240  1.00 27.59 ? 495 HOH B O   1 
HETATM 7620 O O   . HOH F 2 .   ? -32.059 13.296  -6.989  1.00 31.07 ? 496 HOH B O   1 
HETATM 7621 O O   . HOH F 2 .   ? 1.914   21.035  -26.225 1.00 26.67 ? 497 HOH B O   1 
HETATM 7622 O O   . HOH F 2 .   ? -30.905 17.010  -24.322 1.00 31.09 ? 498 HOH B O   1 
HETATM 7623 O O   . HOH F 2 .   ? -12.283 17.680  -23.106 1.00 22.67 ? 499 HOH B O   1 
HETATM 7624 O O   . HOH F 2 .   ? -41.188 -4.217  -17.657 1.00 39.67 ? 500 HOH B O   1 
HETATM 7625 O O   . HOH F 2 .   ? -0.190  17.018  -12.426 1.00 31.10 ? 501 HOH B O   1 
HETATM 7626 O O   . HOH F 2 .   ? -9.575  6.150   -29.136 1.00 27.66 ? 502 HOH B O   1 
HETATM 7627 O O   . HOH F 2 .   ? -9.709  -9.749  -11.251 1.00 27.37 ? 503 HOH B O   1 
HETATM 7628 O O   . HOH F 2 .   ? -33.015 7.499   0.360   1.00 38.07 ? 504 HOH B O   1 
HETATM 7629 O O   . HOH F 2 .   ? 1.210   16.117  -18.282 1.00 35.56 ? 505 HOH B O   1 
HETATM 7630 O O   . HOH F 2 .   ? -2.705  21.562  -23.396 1.00 30.85 ? 506 HOH B O   1 
HETATM 7631 O O   . HOH F 2 .   ? -30.072 12.948  -36.017 1.00 44.67 ? 507 HOH B O   1 
HETATM 7632 O O   . HOH F 2 .   ? -38.765 -8.895  -3.792  1.00 36.82 ? 508 HOH B O   1 
HETATM 7633 O O   . HOH F 2 .   ? -2.746  17.336  -2.292  1.00 42.91 ? 509 HOH B O   1 
HETATM 7634 O O   . HOH F 2 .   ? -23.139 -8.660  12.537  1.00 33.92 ? 510 HOH B O   1 
HETATM 7635 O O   . HOH F 2 .   ? -2.526  -3.436  -12.465 1.00 46.48 ? 511 HOH B O   1 
HETATM 7636 O O   . HOH F 2 .   ? -34.804 -19.675 -11.184 1.00 26.02 ? 512 HOH B O   1 
HETATM 7637 O O   . HOH F 2 .   ? -9.841  16.131  -31.708 1.00 28.60 ? 513 HOH B O   1 
HETATM 7638 O O   . HOH G 2 .   ? 5.644   6.034   -27.024 1.00 33.02 ? 301 HOH C O   1 
HETATM 7639 O O   . HOH G 2 .   ? 13.682  -5.676  -38.298 1.00 29.51 ? 302 HOH C O   1 
HETATM 7640 O O   . HOH G 2 .   ? -4.355  -28.428 -33.120 1.00 25.37 ? 303 HOH C O   1 
HETATM 7641 O O   . HOH G 2 .   ? -24.820 -12.946 -42.527 1.00 28.81 ? 304 HOH C O   1 
HETATM 7642 O O   . HOH G 2 .   ? -1.275  6.779   -23.412 1.00 31.13 ? 305 HOH C O   1 
HETATM 7643 O O   . HOH G 2 .   ? 5.019   -22.807 -26.494 1.00 19.84 ? 306 HOH C O   1 
HETATM 7644 O O   . HOH G 2 .   ? 4.607   -11.167 -12.208 1.00 29.90 ? 307 HOH C O   1 
HETATM 7645 O O   . HOH G 2 .   ? -20.529 -14.549 -49.527 1.00 43.97 ? 308 HOH C O   1 
HETATM 7646 O O   . HOH G 2 .   ? 15.082  -16.056 -26.081 1.00 26.91 ? 309 HOH C O   1 
HETATM 7647 O O   . HOH G 2 .   ? -12.374 -17.956 -33.140 1.00 16.20 ? 310 HOH C O   1 
HETATM 7648 O O   . HOH G 2 .   ? 10.018  -19.792 -38.169 1.00 30.30 ? 311 HOH C O   1 
HETATM 7649 O O   . HOH G 2 .   ? 6.116   -8.196  -21.260 1.00 28.67 ? 312 HOH C O   1 
HETATM 7650 O O   . HOH G 2 .   ? -11.043 -32.316 -33.835 1.00 20.56 ? 313 HOH C O   1 
HETATM 7651 O O   . HOH G 2 .   ? -12.781 -8.878  -18.441 1.00 18.68 ? 314 HOH C O   1 
HETATM 7652 O O   . HOH G 2 .   ? -11.295 -24.719 -44.503 1.00 38.04 ? 315 HOH C O   1 
HETATM 7653 O O   . HOH G 2 .   ? -12.409 -13.190 -27.377 1.00 24.70 ? 316 HOH C O   1 
HETATM 7654 O O   . HOH G 2 .   ? -11.632 -2.671  -40.947 1.00 26.79 ? 317 HOH C O   1 
HETATM 7655 O O   . HOH G 2 .   ? -20.711 -23.888 -20.593 1.00 26.66 ? 318 HOH C O   1 
HETATM 7656 O O   . HOH G 2 .   ? -5.024  0.224   -25.109 1.00 24.43 ? 319 HOH C O   1 
HETATM 7657 O O   . HOH G 2 .   ? -8.355  -21.059 -16.179 1.00 42.05 ? 320 HOH C O   1 
HETATM 7658 O O   . HOH G 2 .   ? 6.058   -0.986  -22.726 1.00 34.21 ? 321 HOH C O   1 
HETATM 7659 O O   . HOH G 2 .   ? 11.257  -15.369 -27.895 1.00 22.99 ? 322 HOH C O   1 
HETATM 7660 O O   . HOH G 2 .   ? -3.799  -10.332 -32.386 1.00 11.72 ? 323 HOH C O   1 
HETATM 7661 O O   . HOH G 2 .   ? -22.410 -29.683 -35.127 1.00 31.39 ? 324 HOH C O   1 
HETATM 7662 O O   . HOH G 2 .   ? 12.333  -15.085 -40.725 1.00 32.89 ? 325 HOH C O   1 
HETATM 7663 O O   . HOH G 2 .   ? -10.282 -19.277 -43.452 1.00 22.17 ? 326 HOH C O   1 
HETATM 7664 O O   . HOH G 2 .   ? -5.890  -16.350 -37.114 1.00 15.31 ? 327 HOH C O   1 
HETATM 7665 O O   . HOH G 2 .   ? 7.277   -1.629  -34.559 1.00 21.24 ? 328 HOH C O   1 
HETATM 7666 O O   . HOH G 2 .   ? -19.719 -19.427 -30.591 1.00 15.80 ? 329 HOH C O   1 
HETATM 7667 O O   . HOH G 2 .   ? -5.373  -12.879 -35.735 1.00 11.55 ? 330 HOH C O   1 
HETATM 7668 O O   . HOH G 2 .   ? -17.216 -12.644 -49.293 1.00 48.04 ? 331 HOH C O   1 
HETATM 7669 O O   . HOH G 2 .   ? -1.599  -0.795  -25.796 1.00 21.00 ? 332 HOH C O   1 
HETATM 7670 O O   . HOH G 2 .   ? -6.996  -10.719 -16.023 1.00 17.22 ? 333 HOH C O   1 
HETATM 7671 O O   . HOH G 2 .   ? -6.287  -26.762 -33.216 1.00 19.46 ? 334 HOH C O   1 
HETATM 7672 O O   . HOH G 2 .   ? 2.756   -10.713 -42.494 1.00 15.89 ? 335 HOH C O   1 
HETATM 7673 O O   . HOH G 2 .   ? -3.328  6.814   -25.274 1.00 22.10 ? 336 HOH C O   1 
HETATM 7674 O O   . HOH G 2 .   ? -8.290  -20.182 -46.808 1.00 40.83 ? 337 HOH C O   1 
HETATM 7675 O O   . HOH G 2 .   ? -27.394 -5.727  -30.888 1.00 45.10 ? 338 HOH C O   1 
HETATM 7676 O O   . HOH G 2 .   ? 12.464  -13.445 -30.773 1.00 27.26 ? 339 HOH C O   1 
HETATM 7677 O O   . HOH G 2 .   ? -6.892  -30.414 -21.015 1.00 28.66 ? 340 HOH C O   1 
HETATM 7678 O O   . HOH G 2 .   ? -14.532 -0.137  -29.277 1.00 25.33 ? 341 HOH C O   1 
HETATM 7679 O O   . HOH G 2 .   ? -21.602 -17.312 -35.907 1.00 25.19 ? 342 HOH C O   1 
HETATM 7680 O O   . HOH G 2 .   ? -14.687 -30.752 -22.786 1.00 24.78 ? 343 HOH C O   1 
HETATM 7681 O O   . HOH G 2 .   ? -3.995  -13.238 -44.256 1.00 22.84 ? 344 HOH C O   1 
HETATM 7682 O O   . HOH G 2 .   ? 5.642   6.090   -29.853 1.00 27.75 ? 345 HOH C O   1 
HETATM 7683 O O   . HOH G 2 .   ? 4.634   -2.538  -25.105 1.00 17.60 ? 346 HOH C O   1 
HETATM 7684 O O   . HOH G 2 .   ? -4.431  -30.252 -35.172 1.00 41.50 ? 347 HOH C O   1 
HETATM 7685 O O   . HOH G 2 .   ? 3.726   -6.713  -20.371 1.00 22.05 ? 348 HOH C O   1 
HETATM 7686 O O   . HOH G 2 .   ? -17.410 -6.980  -39.989 1.00 18.35 ? 349 HOH C O   1 
HETATM 7687 O O   . HOH G 2 .   ? 4.145   12.784  -26.314 1.00 35.17 ? 350 HOH C O   1 
HETATM 7688 O O   . HOH G 2 .   ? 5.228   -10.293 -18.197 1.00 20.27 ? 351 HOH C O   1 
HETATM 7689 O O   . HOH G 2 .   ? -18.916 -29.262 -22.421 1.00 30.46 ? 352 HOH C O   1 
HETATM 7690 O O   . HOH G 2 .   ? -15.992 -8.579  -29.875 1.00 15.80 ? 353 HOH C O   1 
HETATM 7691 O O   . HOH G 2 .   ? 11.342  -12.288 -14.095 1.00 37.46 ? 354 HOH C O   1 
HETATM 7692 O O   . HOH G 2 .   ? -16.703 -31.021 -24.337 1.00 25.89 ? 355 HOH C O   1 
HETATM 7693 O O   . HOH G 2 .   ? -18.225 -24.052 -22.683 1.00 21.69 ? 356 HOH C O   1 
HETATM 7694 O O   . HOH G 2 .   ? -12.265 -15.572 -28.270 1.00 17.37 ? 357 HOH C O   1 
HETATM 7695 O O   . HOH G 2 .   ? -6.692  -2.728  -27.395 1.00 17.09 ? 358 HOH C O   1 
HETATM 7696 O O   . HOH G 2 .   ? 9.584   -15.514 -20.702 1.00 25.79 ? 359 HOH C O   1 
HETATM 7697 O O   . HOH G 2 .   ? 11.308  -6.554  -30.240 1.00 25.42 ? 360 HOH C O   1 
HETATM 7698 O O   . HOH G 2 .   ? -13.006 0.083   -26.340 1.00 23.76 ? 361 HOH C O   1 
HETATM 7699 O O   . HOH G 2 .   ? -5.223  -7.678  -30.170 1.00 11.87 ? 362 HOH C O   1 
HETATM 7700 O O   . HOH G 2 .   ? 8.949   -12.239 -40.467 1.00 23.27 ? 363 HOH C O   1 
HETATM 7701 O O   . HOH G 2 .   ? -11.494 -27.216 -17.124 1.00 31.59 ? 364 HOH C O   1 
HETATM 7702 O O   . HOH G 2 .   ? -18.472 -28.204 -16.329 1.00 29.72 ? 365 HOH C O   1 
HETATM 7703 O O   . HOH G 2 .   ? 1.286   -21.211 -14.666 1.00 32.83 ? 366 HOH C O   1 
HETATM 7704 O O   . HOH G 2 .   ? 9.987   -6.901  -43.214 1.00 28.71 ? 367 HOH C O   1 
HETATM 7705 O O   . HOH G 2 .   ? -34.639 -21.130 -29.066 1.00 48.76 ? 368 HOH C O   1 
HETATM 7706 O O   . HOH G 2 .   ? 0.290   -10.953 -48.558 1.00 25.98 ? 369 HOH C O   1 
HETATM 7707 O O   . HOH G 2 .   ? -10.401 -0.950  -29.999 1.00 17.79 ? 370 HOH C O   1 
HETATM 7708 O O   . HOH G 2 .   ? -17.112 -1.668  -30.144 1.00 24.48 ? 371 HOH C O   1 
HETATM 7709 O O   . HOH G 2 .   ? -3.937  -2.248  -26.108 1.00 20.02 ? 372 HOH C O   1 
HETATM 7710 O O   . HOH G 2 .   ? 7.146   4.046   -25.032 1.00 32.93 ? 373 HOH C O   1 
HETATM 7711 O O   . HOH G 2 .   ? -5.940  -5.396  -14.599 1.00 37.69 ? 374 HOH C O   1 
HETATM 7712 O O   . HOH G 2 .   ? -24.950 -21.804 -29.716 1.00 32.05 ? 375 HOH C O   1 
HETATM 7713 O O   . HOH G 2 .   ? 11.954  1.139   -27.489 1.00 31.37 ? 376 HOH C O   1 
HETATM 7714 O O   . HOH G 2 .   ? -15.525 -8.547  -43.339 1.00 18.73 ? 377 HOH C O   1 
HETATM 7715 O O   . HOH G 2 .   ? -4.388  -11.921 -12.275 1.00 34.23 ? 378 HOH C O   1 
HETATM 7716 O O   . HOH G 2 .   ? -4.127  -6.252  -32.242 1.00 12.89 ? 379 HOH C O   1 
HETATM 7717 O O   . HOH G 2 .   ? -6.786  -16.537 -34.418 1.00 11.46 ? 380 HOH C O   1 
HETATM 7718 O O   . HOH G 2 .   ? 2.408   0.885   -42.971 1.00 25.48 ? 381 HOH C O   1 
HETATM 7719 O O   . HOH G 2 .   ? -14.315 -12.575 -28.298 1.00 22.19 ? 382 HOH C O   1 
HETATM 7720 O O   . HOH G 2 .   ? 12.407  -10.349 -27.438 1.00 25.20 ? 383 HOH C O   1 
HETATM 7721 O O   . HOH G 2 .   ? 3.410   -23.032 -29.565 1.00 20.74 ? 384 HOH C O   1 
HETATM 7722 O O   . HOH G 2 .   ? -16.735 -5.584  -37.051 1.00 20.76 ? 385 HOH C O   1 
HETATM 7723 O O   . HOH G 2 .   ? -23.299 -1.323  -31.487 1.00 32.49 ? 386 HOH C O   1 
HETATM 7724 O O   . HOH G 2 .   ? 10.020  -23.031 -22.394 1.00 26.16 ? 387 HOH C O   1 
HETATM 7725 O O   . HOH G 2 .   ? -3.520  8.903   -31.717 1.00 27.80 ? 388 HOH C O   1 
HETATM 7726 O O   . HOH G 2 .   ? -1.250  -13.360 -49.739 1.00 20.87 ? 389 HOH C O   1 
HETATM 7727 O O   . HOH G 2 .   ? -13.591 -28.944 -17.248 1.00 38.03 ? 390 HOH C O   1 
HETATM 7728 O O   . HOH G 2 .   ? 0.350   -1.999  -41.788 1.00 16.43 ? 391 HOH C O   1 
HETATM 7729 O O   . HOH G 2 .   ? -4.577  -3.378  -17.730 1.00 37.17 ? 392 HOH C O   1 
HETATM 7730 O O   . HOH G 2 .   ? -19.260 -30.148 -37.380 1.00 29.20 ? 393 HOH C O   1 
HETATM 7731 O O   . HOH G 2 .   ? -19.929 -34.513 -38.207 1.00 49.33 ? 394 HOH C O   1 
HETATM 7732 O O   . HOH G 2 .   ? -2.231  -9.926  -46.115 1.00 25.46 ? 395 HOH C O   1 
HETATM 7733 O O   . HOH G 2 .   ? -20.604 -31.404 -22.802 1.00 37.40 ? 396 HOH C O   1 
HETATM 7734 O O   . HOH G 2 .   ? 13.823  -2.785  -30.953 1.00 36.72 ? 397 HOH C O   1 
HETATM 7735 O O   . HOH G 2 .   ? 1.623   -0.359  -19.405 1.00 29.07 ? 398 HOH C O   1 
HETATM 7736 O O   . HOH G 2 .   ? -0.923  4.522   -43.670 1.00 37.92 ? 399 HOH C O   1 
HETATM 7737 O O   . HOH G 2 .   ? -6.688  -4.699  -18.954 1.00 21.71 ? 400 HOH C O   1 
HETATM 7738 O O   . HOH G 2 .   ? -11.334 -4.512  -16.510 1.00 23.37 ? 401 HOH C O   1 
HETATM 7739 O O   . HOH G 2 .   ? 10.034  -18.541 -20.920 1.00 41.26 ? 402 HOH C O   1 
HETATM 7740 O O   . HOH G 2 .   ? 6.343   -22.169 -13.035 1.00 44.32 ? 403 HOH C O   1 
HETATM 7741 O O   . HOH G 2 .   ? -18.200 -28.101 -44.509 1.00 41.48 ? 404 HOH C O   1 
HETATM 7742 O O   . HOH G 2 .   ? -2.235  4.352   -35.563 1.00 21.17 ? 405 HOH C O   1 
HETATM 7743 O O   . HOH G 2 .   ? -0.037  2.207   -42.754 1.00 25.35 ? 406 HOH C O   1 
HETATM 7744 O O   . HOH G 2 .   ? 14.591  -13.404 -24.565 1.00 28.49 ? 407 HOH C O   1 
HETATM 7745 O O   . HOH G 2 .   ? -17.391 -29.839 -20.251 1.00 32.60 ? 408 HOH C O   1 
HETATM 7746 O O   . HOH G 2 .   ? -15.521 -33.096 -25.858 1.00 28.91 ? 409 HOH C O   1 
HETATM 7747 O O   . HOH G 2 .   ? -8.141  -18.773 -33.954 1.00 14.12 ? 410 HOH C O   1 
HETATM 7748 O O   . HOH G 2 .   ? -0.155  -17.212 -8.349  1.00 39.16 ? 411 HOH C O   1 
HETATM 7749 O O   . HOH G 2 .   ? 13.017  -17.601 -41.394 1.00 41.07 ? 412 HOH C O   1 
HETATM 7750 O O   . HOH G 2 .   ? -6.822  -26.168 -18.549 1.00 25.33 ? 413 HOH C O   1 
HETATM 7751 O O   . HOH G 2 .   ? 13.383  -1.100  -39.075 1.00 32.82 ? 414 HOH C O   1 
HETATM 7752 O O   . HOH G 2 .   ? -23.408 -11.975 -45.546 1.00 37.07 ? 415 HOH C O   1 
HETATM 7753 O O   . HOH G 2 .   ? 11.894  -3.025  -27.431 1.00 28.38 ? 416 HOH C O   1 
HETATM 7754 O O   . HOH G 2 .   ? 13.302  -7.002  -31.775 1.00 42.69 ? 417 HOH C O   1 
HETATM 7755 O O   . HOH G 2 .   ? -33.126 -15.744 -25.978 1.00 41.99 ? 418 HOH C O   1 
HETATM 7756 O O   . HOH G 2 .   ? -16.082 -2.697  -40.219 1.00 27.84 ? 419 HOH C O   1 
HETATM 7757 O O   . HOH G 2 .   ? -15.058 -11.506 -30.889 1.00 20.26 ? 420 HOH C O   1 
HETATM 7758 O O   . HOH G 2 .   ? -16.065 -28.452 -39.576 1.00 23.79 ? 421 HOH C O   1 
HETATM 7759 O O   . HOH G 2 .   ? 8.747   -17.834 -40.678 1.00 39.20 ? 422 HOH C O   1 
HETATM 7760 O O   . HOH G 2 .   ? 3.039   6.554   -32.961 1.00 27.14 ? 423 HOH C O   1 
HETATM 7761 O O   . HOH G 2 .   ? -16.592 -5.404  -27.585 1.00 19.22 ? 424 HOH C O   1 
HETATM 7762 O O   . HOH G 2 .   ? -3.634  -15.365 -43.080 1.00 22.94 ? 425 HOH C O   1 
HETATM 7763 O O   . HOH G 2 .   ? 15.765  -10.266 -37.333 1.00 40.25 ? 426 HOH C O   1 
HETATM 7764 O O   . HOH G 2 .   ? -23.164 -20.192 -26.141 1.00 27.57 ? 427 HOH C O   1 
HETATM 7765 O O   . HOH G 2 .   ? 9.046   -19.074 -35.913 1.00 32.27 ? 428 HOH C O   1 
HETATM 7766 O O   . HOH G 2 .   ? -1.918  -7.117  -12.765 1.00 27.66 ? 429 HOH C O   1 
HETATM 7767 O O   . HOH G 2 .   ? 14.665  -15.296 -33.268 1.00 16.84 ? 430 HOH C O   1 
HETATM 7768 O O   . HOH G 2 .   ? -9.576  -36.360 -30.460 1.00 20.75 ? 431 HOH C O   1 
HETATM 7769 O O   . HOH G 2 .   ? 1.183   -26.002 -23.069 1.00 31.30 ? 432 HOH C O   1 
HETATM 7770 O O   . HOH G 2 .   ? 10.160  0.455   -24.498 1.00 36.15 ? 433 HOH C O   1 
HETATM 7771 O O   . HOH G 2 .   ? 2.057   -3.179  -43.594 1.00 21.69 ? 434 HOH C O   1 
HETATM 7772 O O   . HOH G 2 .   ? -8.288  4.245   -24.494 1.00 25.43 ? 435 HOH C O   1 
HETATM 7773 O O   . HOH G 2 .   ? -5.912  -32.646 -36.398 1.00 35.07 ? 436 HOH C O   1 
HETATM 7774 O O   . HOH G 2 .   ? -3.998  0.362   -40.095 1.00 26.09 ? 437 HOH C O   1 
HETATM 7775 O O   . HOH G 2 .   ? -14.798 -33.709 -27.854 1.00 36.04 ? 438 HOH C O   1 
HETATM 7776 O O   . HOH G 2 .   ? -5.605  -26.859 -20.763 1.00 26.66 ? 439 HOH C O   1 
HETATM 7777 O O   . HOH G 2 .   ? 1.628   -23.626 -34.471 1.00 25.11 ? 440 HOH C O   1 
HETATM 7778 O O   . HOH G 2 .   ? -8.286  -3.030  -20.136 1.00 26.34 ? 441 HOH C O   1 
HETATM 7779 O O   . HOH G 2 .   ? -15.059 -30.774 -20.423 1.00 33.39 ? 442 HOH C O   1 
HETATM 7780 O O   . HOH G 2 .   ? -23.664 -26.118 -44.555 1.00 50.62 ? 443 HOH C O   1 
HETATM 7781 O O   . HOH G 2 .   ? 7.423   5.181   -32.633 1.00 35.62 ? 444 HOH C O   1 
HETATM 7782 O O   . HOH G 2 .   ? 3.238   -5.870  -23.282 1.00 11.58 ? 445 HOH C O   1 
HETATM 7783 O O   . HOH G 2 .   ? -0.493  11.879  -28.596 1.00 36.86 ? 446 HOH C O   1 
HETATM 7784 O O   . HOH G 2 .   ? -13.474 -13.983 -12.091 1.00 43.30 ? 447 HOH C O   1 
HETATM 7785 O O   . HOH G 2 .   ? 3.815   -2.601  -21.506 1.00 34.61 ? 448 HOH C O   1 
HETATM 7786 O O   . HOH G 2 .   ? -11.132 -35.097 -31.547 1.00 34.80 ? 449 HOH C O   1 
HETATM 7787 O O   . HOH G 2 .   ? 4.341   -2.024  -45.320 1.00 34.94 ? 450 HOH C O   1 
HETATM 7788 O O   . HOH G 2 .   ? -19.508 -8.516  -23.002 1.00 24.77 ? 451 HOH C O   1 
HETATM 7789 O O   . HOH G 2 .   ? -9.106  3.940   -27.599 1.00 26.50 ? 452 HOH C O   1 
HETATM 7790 O O   . HOH G 2 .   ? -12.266 -1.169  -44.565 1.00 36.53 ? 453 HOH C O   1 
HETATM 7791 O O   . HOH G 2 .   ? 0.388   -15.051 -50.093 1.00 37.46 ? 454 HOH C O   1 
HETATM 7792 O O   . HOH G 2 .   ? 10.554  -6.623  -45.633 1.00 42.81 ? 455 HOH C O   1 
HETATM 7793 O O   . HOH G 2 .   ? -23.609 -24.005 -24.826 1.00 39.99 ? 456 HOH C O   1 
HETATM 7794 O O   . HOH G 2 .   ? -14.939 -21.008 -15.608 1.00 44.75 ? 457 HOH C O   1 
HETATM 7795 O O   . HOH G 2 .   ? 8.279   -12.234 -46.480 1.00 42.91 ? 458 HOH C O   1 
HETATM 7796 O O   . HOH G 2 .   ? -18.496 -29.823 -39.814 1.00 46.02 ? 459 HOH C O   1 
HETATM 7797 O O   . HOH G 2 .   ? -24.423 -22.698 -26.947 1.00 41.08 ? 460 HOH C O   1 
HETATM 7798 O O   . HOH G 2 .   ? 14.490  -15.375 -39.484 1.00 45.36 ? 461 HOH C O   1 
HETATM 7799 O O   . HOH G 2 .   ? -1.164  -5.872  -14.853 1.00 27.84 ? 462 HOH C O   1 
HETATM 7800 O O   . HOH G 2 .   ? -10.781 0.269   -45.523 1.00 32.80 ? 463 HOH C O   1 
HETATM 7801 O O   . HOH G 2 .   ? 1.198   11.486  -29.966 1.00 49.29 ? 464 HOH C O   1 
HETATM 7802 O O   . HOH G 2 .   ? -17.242 -2.780  -27.519 1.00 25.59 ? 465 HOH C O   1 
HETATM 7803 O O   . HOH G 2 .   ? 16.026  -12.284 -31.384 1.00 29.79 ? 466 HOH C O   1 
HETATM 7804 O O   . HOH G 2 .   ? -12.191 1.284   -29.894 1.00 26.08 ? 467 HOH C O   1 
HETATM 7805 O O   . HOH G 2 .   ? 9.632   -20.988 -20.426 1.00 32.71 ? 468 HOH C O   1 
HETATM 7806 O O   . HOH G 2 .   ? -7.728  -12.554 -44.394 1.00 37.95 ? 469 HOH C O   1 
HETATM 7807 O O   . HOH G 2 .   ? 9.840   -4.343  -23.257 1.00 35.61 ? 470 HOH C O   1 
HETATM 7808 O O   . HOH G 2 .   ? 3.156   6.035   -36.048 1.00 35.30 ? 471 HOH C O   1 
HETATM 7809 O O   . HOH G 2 .   ? 9.247   -10.614 -17.664 1.00 37.36 ? 472 HOH C O   1 
HETATM 7810 O O   . HOH G 2 .   ? -0.236  5.510   -35.501 1.00 32.96 ? 473 HOH C O   1 
HETATM 7811 O O   . HOH G 2 .   ? -9.651  -26.773 -44.232 1.00 36.89 ? 474 HOH C O   1 
HETATM 7812 O O   . HOH G 2 .   ? -18.112 0.600   -31.350 1.00 32.57 ? 475 HOH C O   1 
HETATM 7813 O O   . HOH G 2 .   ? -15.222 -14.748 -28.107 1.00 36.94 ? 476 HOH C O   1 
HETATM 7814 O O   . HOH G 2 .   ? 4.193   8.280   -30.694 1.00 33.85 ? 477 HOH C O   1 
HETATM 7815 O O   . HOH G 2 .   ? 12.715  0.811   -39.968 1.00 43.42 ? 478 HOH C O   1 
HETATM 7816 O O   . HOH G 2 .   ? 15.670  -17.932 -40.498 1.00 38.89 ? 479 HOH C O   1 
HETATM 7817 O O   . HOH G 2 .   ? 9.867   -8.743  -19.740 1.00 41.08 ? 480 HOH C O   1 
HETATM 7818 O O   . HOH G 2 .   ? -2.047  11.259  -31.250 1.00 46.20 ? 481 HOH C O   1 
HETATM 7819 O O   . HOH G 2 .   ? 6.476   -9.730  -16.061 1.00 39.62 ? 482 HOH C O   1 
HETATM 7820 O O   . HOH G 2 .   ? 5.477   -4.786  -24.157 1.00 22.80 ? 483 HOH C O   1 
HETATM 7821 O O   . HOH G 2 .   ? 3.679   -22.928 -20.273 1.00 27.80 ? 484 HOH C O   1 
HETATM 7822 O O   . HOH G 2 .   ? 2.661   -15.073 -44.522 1.00 35.50 ? 485 HOH C O   1 
HETATM 7823 O O   . HOH G 2 .   ? -11.326 3.070   -27.843 1.00 30.51 ? 486 HOH C O   1 
HETATM 7824 O O   . HOH G 2 .   ? -9.472  6.424   -36.825 1.00 29.71 ? 487 HOH C O   1 
HETATM 7825 O O   . HOH G 2 .   ? 7.760   -4.047  -22.323 1.00 34.04 ? 488 HOH C O   1 
HETATM 7826 O O   . HOH G 2 .   ? -26.462 -1.167  -33.450 1.00 41.10 ? 489 HOH C O   1 
HETATM 7827 O O   . HOH G 2 .   ? 14.959  -11.876 -26.365 1.00 42.52 ? 490 HOH C O   1 
HETATM 7828 O O   . HOH G 2 .   ? 13.433  -3.524  -25.675 1.00 45.76 ? 491 HOH C O   1 
HETATM 7829 O O   . HOH G 2 .   ? 11.877  -17.615 -19.786 1.00 35.49 ? 492 HOH C O   1 
HETATM 7830 O O   . HOH G 2 .   ? 5.677   -7.501  -15.265 1.00 40.39 ? 493 HOH C O   1 
HETATM 7831 O O   . HOH G 2 .   ? -7.916  -11.555 -46.443 1.00 31.05 ? 494 HOH C O   1 
HETATM 7832 O O   . HOH G 2 .   ? 2.459   -0.031  -45.930 1.00 32.97 ? 495 HOH C O   1 
HETATM 7833 O O   . HOH G 2 .   ? 0.802   -4.522  -15.395 1.00 38.89 ? 496 HOH C O   1 
HETATM 7834 O O   . HOH H 2 .   ? -24.929 11.533  -71.838 1.00 32.88 ? 301 HOH D O   1 
HETATM 7835 O O   . HOH H 2 .   ? -18.615 24.986  -66.612 1.00 44.59 ? 302 HOH D O   1 
HETATM 7836 O O   . HOH H 2 .   ? -3.208  1.689   -84.026 1.00 36.42 ? 303 HOH D O   1 
HETATM 7837 O O   . HOH H 2 .   ? -3.042  14.773  -65.179 1.00 23.33 ? 304 HOH D O   1 
HETATM 7838 O O   . HOH H 2 .   ? -27.431 13.135  -65.804 1.00 28.68 ? 305 HOH D O   1 
HETATM 7839 O O   . HOH H 2 .   ? -9.008  16.980  -55.429 1.00 28.76 ? 306 HOH D O   1 
HETATM 7840 O O   . HOH H 2 .   ? -8.676  -16.788 -67.861 1.00 23.31 ? 307 HOH D O   1 
HETATM 7841 O O   . HOH H 2 .   ? -0.783  10.054  -77.872 1.00 40.58 ? 308 HOH D O   1 
HETATM 7842 O O   . HOH H 2 .   ? 8.120   2.902   -51.607 1.00 28.98 ? 309 HOH D O   1 
HETATM 7843 O O   . HOH H 2 .   ? 9.353   -6.252  -55.448 1.00 26.87 ? 310 HOH D O   1 
HETATM 7844 O O   . HOH H 2 .   ? 3.207   10.749  -70.730 1.00 36.00 ? 311 HOH D O   1 
HETATM 7845 O O   . HOH H 2 .   ? -11.946 19.406  -50.083 1.00 34.23 ? 312 HOH D O   1 
HETATM 7846 O O   . HOH H 2 .   ? -0.434  -13.492 -58.221 1.00 20.62 ? 313 HOH D O   1 
HETATM 7847 O O   . HOH H 2 .   ? -7.483  7.896   -81.872 1.00 26.69 ? 314 HOH D O   1 
HETATM 7848 O O   . HOH H 2 .   ? -19.953 -1.688  -70.736 1.00 33.49 ? 315 HOH D O   1 
HETATM 7849 O O   . HOH H 2 .   ? -14.329 19.437  -50.546 1.00 30.48 ? 316 HOH D O   1 
HETATM 7850 O O   . HOH H 2 .   ? -17.165 6.339   -55.316 1.00 18.53 ? 317 HOH D O   1 
HETATM 7851 O O   . HOH H 2 .   ? -10.150 -8.164  -64.813 1.00 16.93 ? 318 HOH D O   1 
HETATM 7852 O O   . HOH H 2 .   ? -26.556 17.565  -50.974 1.00 27.62 ? 319 HOH D O   1 
HETATM 7853 O O   . HOH H 2 .   ? -0.903  -16.626 -66.970 1.00 23.08 ? 320 HOH D O   1 
HETATM 7854 O O   . HOH H 2 .   ? -0.664  12.074  -63.860 1.00 16.79 ? 321 HOH D O   1 
HETATM 7855 O O   . HOH H 2 .   ? -13.115 -10.024 -43.792 1.00 19.88 ? 322 HOH D O   1 
HETATM 7856 O O   . HOH H 2 .   ? 0.708   -14.885 -68.792 1.00 24.95 ? 323 HOH D O   1 
HETATM 7857 O O   . HOH H 2 .   ? -10.651 -3.430  -60.394 1.00 9.85  ? 324 HOH D O   1 
HETATM 7858 O O   . HOH H 2 .   ? 11.093  3.058   -55.101 1.00 30.18 ? 325 HOH D O   1 
HETATM 7859 O O   . HOH H 2 .   ? -16.710 -11.986 -57.721 1.00 44.93 ? 326 HOH D O   1 
HETATM 7860 O O   . HOH H 2 .   ? -8.662  17.936  -53.323 1.00 37.01 ? 327 HOH D O   1 
HETATM 7861 O O   . HOH H 2 .   ? -1.087  -1.864  -48.884 1.00 22.14 ? 328 HOH D O   1 
HETATM 7862 O O   . HOH H 2 .   ? -15.900 -10.104 -60.723 1.00 19.07 ? 329 HOH D O   1 
HETATM 7863 O O   . HOH H 2 .   ? -5.959  -16.103 -71.865 1.00 23.78 ? 330 HOH D O   1 
HETATM 7864 O O   . HOH H 2 .   ? -14.330 0.780   -73.882 1.00 13.62 ? 331 HOH D O   1 
HETATM 7865 O O   . HOH H 2 .   ? -8.782  -0.980  -58.170 1.00 10.92 ? 332 HOH D O   1 
HETATM 7866 O O   . HOH H 2 .   ? -4.874  -18.191 -50.249 1.00 44.52 ? 333 HOH D O   1 
HETATM 7867 O O   . HOH H 2 .   ? 6.904   2.586   -64.839 1.00 35.98 ? 334 HOH D O   1 
HETATM 7868 O O   . HOH H 2 .   ? 3.187   -10.863 -68.969 1.00 28.78 ? 335 HOH D O   1 
HETATM 7869 O O   . HOH H 2 .   ? -15.676 20.792  -53.532 1.00 21.91 ? 336 HOH D O   1 
HETATM 7870 O O   . HOH H 2 .   ? 2.871   5.388   -70.953 1.00 21.14 ? 337 HOH D O   1 
HETATM 7871 O O   . HOH H 2 .   ? -2.510  11.488  -75.129 1.00 35.29 ? 338 HOH D O   1 
HETATM 7872 O O   . HOH H 2 .   ? -19.291 -4.021  -74.106 1.00 24.75 ? 339 HOH D O   1 
HETATM 7873 O O   . HOH H 2 .   ? -32.278 8.541   -64.877 1.00 32.41 ? 340 HOH D O   1 
HETATM 7874 O O   . HOH H 2 .   ? -0.555  -2.169  -70.760 1.00 27.68 ? 341 HOH D O   1 
HETATM 7875 O O   . HOH H 2 .   ? -0.528  -9.142  -70.098 1.00 25.26 ? 342 HOH D O   1 
HETATM 7876 O O   . HOH H 2 .   ? 2.296   -9.898  -58.468 1.00 15.33 ? 343 HOH D O   1 
HETATM 7877 O O   . HOH H 2 .   ? -2.229  -15.043 -57.000 1.00 36.29 ? 344 HOH D O   1 
HETATM 7878 O O   . HOH H 2 .   ? 5.567   -4.762  -62.763 1.00 19.19 ? 345 HOH D O   1 
HETATM 7879 O O   . HOH H 2 .   ? 5.529   4.344   -64.294 1.00 24.19 ? 346 HOH D O   1 
HETATM 7880 O O   . HOH H 2 .   ? -12.721 -8.397  -63.465 1.00 17.72 ? 347 HOH D O   1 
HETATM 7881 O O   . HOH H 2 .   ? -21.119 -5.114  -48.839 1.00 23.26 ? 348 HOH D O   1 
HETATM 7882 O O   . HOH H 2 .   ? -0.367  -16.858 -64.217 1.00 22.24 ? 349 HOH D O   1 
HETATM 7883 O O   . HOH H 2 .   ? -19.712 1.258   -60.041 1.00 23.73 ? 350 HOH D O   1 
HETATM 7884 O O   . HOH H 2 .   ? 0.987   -2.135  -68.807 1.00 26.06 ? 351 HOH D O   1 
HETATM 7885 O O   . HOH H 2 .   ? -10.158 4.581   -52.660 1.00 13.01 ? 352 HOH D O   1 
HETATM 7886 O O   . HOH H 2 .   ? 2.053   -11.936 -50.788 1.00 24.18 ? 353 HOH D O   1 
HETATM 7887 O O   . HOH H 2 .   ? -25.379 18.282  -64.260 1.00 27.46 ? 354 HOH D O   1 
HETATM 7888 O O   . HOH H 2 .   ? -21.251 -2.621  -58.958 1.00 15.18 ? 355 HOH D O   1 
HETATM 7889 O O   . HOH H 2 .   ? 9.466   7.386   -67.469 1.00 40.76 ? 356 HOH D O   1 
HETATM 7890 O O   . HOH H 2 .   ? -10.144 -12.997 -48.977 1.00 38.95 ? 357 HOH D O   1 
HETATM 7891 O O   . HOH H 2 .   ? -11.200 -10.363 -66.048 1.00 21.32 ? 358 HOH D O   1 
HETATM 7892 O O   . HOH H 2 .   ? -3.075  1.775   -79.085 1.00 25.65 ? 359 HOH D O   1 
HETATM 7893 O O   . HOH H 2 .   ? -10.913 15.182  -55.482 1.00 19.12 ? 360 HOH D O   1 
HETATM 7894 O O   . HOH H 2 .   ? -31.003 -0.530  -44.646 1.00 40.79 ? 361 HOH D O   1 
HETATM 7895 O O   . HOH H 2 .   ? -13.699 6.862   -45.424 1.00 22.59 ? 362 HOH D O   1 
HETATM 7896 O O   . HOH H 2 .   ? -8.244  -9.714  -65.940 1.00 17.13 ? 363 HOH D O   1 
HETATM 7897 O O   . HOH H 2 .   ? -24.158 19.329  -66.329 1.00 28.81 ? 364 HOH D O   1 
HETATM 7898 O O   . HOH H 2 .   ? -3.125  -3.329  -71.461 1.00 20.30 ? 365 HOH D O   1 
HETATM 7899 O O   . HOH H 2 .   ? -11.912 2.340   -77.690 1.00 27.64 ? 366 HOH D O   1 
HETATM 7900 O O   . HOH H 2 .   ? -19.767 16.312  -47.715 1.00 23.42 ? 367 HOH D O   1 
HETATM 7901 O O   . HOH H 2 .   ? -7.713  -16.427 -49.065 1.00 38.49 ? 368 HOH D O   1 
HETATM 7902 O O   . HOH H 2 .   ? -25.531 9.713   -39.026 1.00 37.26 ? 369 HOH D O   1 
HETATM 7903 O O   . HOH H 2 .   ? -11.549 -15.075 -70.341 1.00 19.63 ? 370 HOH D O   1 
HETATM 7904 O O   . HOH H 2 .   ? -23.540 18.104  -49.065 1.00 29.42 ? 371 HOH D O   1 
HETATM 7905 O O   . HOH H 2 .   ? -2.321  -17.766 -60.785 1.00 25.10 ? 372 HOH D O   1 
HETATM 7906 O O   . HOH H 2 .   ? -12.852 19.697  -66.790 1.00 28.51 ? 373 HOH D O   1 
HETATM 7907 O O   . HOH H 2 .   ? -20.057 0.122   -57.696 1.00 19.74 ? 374 HOH D O   1 
HETATM 7908 O O   . HOH H 2 .   ? -2.086  11.870  -60.703 1.00 19.13 ? 375 HOH D O   1 
HETATM 7909 O O   . HOH H 2 .   ? -20.886 20.032  -64.164 1.00 24.72 ? 376 HOH D O   1 
HETATM 7910 O O   . HOH H 2 .   ? -19.178 -10.898 -63.779 1.00 22.71 ? 377 HOH D O   1 
HETATM 7911 O O   . HOH H 2 .   ? -9.992  1.345   -54.379 1.00 10.47 ? 378 HOH D O   1 
HETATM 7912 O O   . HOH H 2 .   ? -24.860 20.366  -51.221 1.00 34.02 ? 379 HOH D O   1 
HETATM 7913 O O   . HOH H 2 .   ? -1.742  0.336   -73.339 1.00 15.94 ? 380 HOH D O   1 
HETATM 7914 O O   . HOH H 2 .   ? -30.284 10.151  -57.303 1.00 23.20 ? 381 HOH D O   1 
HETATM 7915 O O   . HOH H 2 .   ? -24.465 13.357  -64.208 1.00 20.36 ? 382 HOH D O   1 
HETATM 7916 O O   . HOH H 2 .   ? -37.716 5.625   -61.076 1.00 43.59 ? 383 HOH D O   1 
HETATM 7917 O O   . HOH H 2 .   ? -1.728  -8.237  -67.201 1.00 12.85 ? 384 HOH D O   1 
HETATM 7918 O O   . HOH H 2 .   ? -24.798 8.004   -56.692 1.00 22.67 ? 385 HOH D O   1 
HETATM 7919 O O   . HOH H 2 .   ? -13.772 15.904  -69.996 1.00 22.20 ? 386 HOH D O   1 
HETATM 7920 O O   . HOH H 2 .   ? -11.523 -5.941  -73.338 1.00 29.71 ? 387 HOH D O   1 
HETATM 7921 O O   . HOH H 2 .   ? -28.793 19.536  -66.401 1.00 42.27 ? 388 HOH D O   1 
HETATM 7922 O O   . HOH H 2 .   ? -22.536 20.068  -62.240 1.00 23.09 ? 389 HOH D O   1 
HETATM 7923 O O   . HOH H 2 .   ? -22.187 -5.538  -61.546 1.00 17.30 ? 390 HOH D O   1 
HETATM 7924 O O   . HOH H 2 .   ? -17.931 -6.599  -68.355 1.00 26.97 ? 391 HOH D O   1 
HETATM 7925 O O   . HOH H 2 .   ? 3.207   8.048   -70.794 1.00 33.41 ? 392 HOH D O   1 
HETATM 7926 O O   . HOH H 2 .   ? -21.123 -6.461  -51.802 1.00 19.74 ? 393 HOH D O   1 
HETATM 7927 O O   . HOH H 2 .   ? -9.219  -5.049  -58.499 1.00 12.78 ? 394 HOH D O   1 
HETATM 7928 O O   . HOH H 2 .   ? 0.172   -11.843 -73.003 1.00 42.28 ? 395 HOH D O   1 
HETATM 7929 O O   . HOH H 2 .   ? 2.944   2.901   -78.683 1.00 42.49 ? 396 HOH D O   1 
HETATM 7930 O O   . HOH H 2 .   ? 7.246   -8.734  -51.697 1.00 28.41 ? 397 HOH D O   1 
HETATM 7931 O O   . HOH H 2 .   ? -7.288  -16.052 -56.939 1.00 20.73 ? 398 HOH D O   1 
HETATM 7932 O O   . HOH H 2 .   ? -22.166 -6.694  -65.393 1.00 34.79 ? 399 HOH D O   1 
HETATM 7933 O O   . HOH H 2 .   ? -5.311  9.779   -79.449 1.00 37.87 ? 400 HOH D O   1 
HETATM 7934 O O   . HOH H 2 .   ? -27.609 -10.964 -57.799 1.00 39.19 ? 401 HOH D O   1 
HETATM 7935 O O   . HOH H 2 .   ? 8.915   -11.299 -55.193 1.00 28.63 ? 402 HOH D O   1 
HETATM 7936 O O   . HOH H 2 .   ? -12.748 7.243   -55.252 1.00 11.46 ? 403 HOH D O   1 
HETATM 7937 O O   . HOH H 2 .   ? -8.285  7.120   -42.084 1.00 52.22 ? 404 HOH D O   1 
HETATM 7938 O O   . HOH H 2 .   ? -15.979 11.492  -72.749 1.00 27.97 ? 405 HOH D O   1 
HETATM 7939 O O   . HOH H 2 .   ? -18.803 -10.292 -53.517 1.00 22.42 ? 406 HOH D O   1 
HETATM 7940 O O   . HOH H 2 .   ? -18.492 17.643  -70.399 1.00 33.24 ? 407 HOH D O   1 
HETATM 7941 O O   . HOH H 2 .   ? -25.628 18.349  -70.052 1.00 33.28 ? 408 HOH D O   1 
HETATM 7942 O O   . HOH H 2 .   ? -6.644  11.593  -75.731 1.00 32.88 ? 409 HOH D O   1 
HETATM 7943 O O   . HOH H 2 .   ? 6.604   -0.515  -65.133 1.00 24.23 ? 410 HOH D O   1 
HETATM 7944 O O   . HOH H 2 .   ? 2.425   -17.960 -64.097 1.00 27.23 ? 411 HOH D O   1 
HETATM 7945 O O   . HOH H 2 .   ? -3.293  -19.552 -66.192 1.00 23.72 ? 412 HOH D O   1 
HETATM 7946 O O   . HOH H 2 .   ? 5.827   -7.698  -66.329 1.00 26.26 ? 413 HOH D O   1 
HETATM 7947 O O   . HOH H 2 .   ? 4.009   7.360   -55.439 1.00 32.68 ? 414 HOH D O   1 
HETATM 7948 O O   . HOH H 2 .   ? -4.210  -6.633  -68.686 1.00 36.96 ? 415 HOH D O   1 
HETATM 7949 O O   . HOH H 2 .   ? -6.922  3.089   -47.043 1.00 22.05 ? 416 HOH D O   1 
HETATM 7950 O O   . HOH H 2 .   ? -11.476 4.865   -55.079 1.00 13.88 ? 417 HOH D O   1 
HETATM 7951 O O   . HOH H 2 .   ? -5.795  -9.743  -72.942 1.00 22.11 ? 418 HOH D O   1 
HETATM 7952 O O   . HOH H 2 .   ? -9.689  -1.951  -78.214 1.00 23.15 ? 419 HOH D O   1 
HETATM 7953 O O   . HOH H 2 .   ? -17.822 4.439   -60.400 1.00 15.98 ? 420 HOH D O   1 
HETATM 7954 O O   . HOH H 2 .   ? -12.140 16.473  -67.537 1.00 23.13 ? 421 HOH D O   1 
HETATM 7955 O O   . HOH H 2 .   ? 5.809   -12.062 -66.587 1.00 33.47 ? 422 HOH D O   1 
HETATM 7956 O O   . HOH H 2 .   ? -26.757 20.510  -63.200 1.00 36.42 ? 423 HOH D O   1 
HETATM 7957 O O   . HOH H 2 .   ? -2.908  -22.018 -66.793 1.00 31.79 ? 424 HOH D O   1 
HETATM 7958 O O   . HOH H 2 .   ? 8.379   2.748   -68.124 1.00 25.25 ? 425 HOH D O   1 
HETATM 7959 O O   . HOH H 2 .   ? 4.374   -3.718  -72.686 1.00 43.05 ? 426 HOH D O   1 
HETATM 7960 O O   . HOH H 2 .   ? 6.601   -5.230  -50.180 1.00 33.95 ? 427 HOH D O   1 
HETATM 7961 O O   . HOH H 2 .   ? -15.821 22.460  -65.137 1.00 35.86 ? 428 HOH D O   1 
HETATM 7962 O O   . HOH H 2 .   ? 9.511   9.025   -51.984 1.00 29.78 ? 429 HOH D O   1 
HETATM 7963 O O   . HOH H 2 .   ? -10.132 10.598  -43.750 1.00 47.68 ? 430 HOH D O   1 
HETATM 7964 O O   . HOH H 2 .   ? -3.849  -10.346 -50.447 1.00 14.95 ? 431 HOH D O   1 
HETATM 7965 O O   . HOH H 2 .   ? 1.986   -16.434 -61.349 1.00 29.37 ? 432 HOH D O   1 
HETATM 7966 O O   . HOH H 2 .   ? -3.202  12.113  -55.895 1.00 34.58 ? 433 HOH D O   1 
HETATM 7967 O O   . HOH H 2 .   ? -3.023  -7.566  -70.421 1.00 25.50 ? 434 HOH D O   1 
HETATM 7968 O O   . HOH H 2 .   ? -8.398  -0.388  -80.528 1.00 23.24 ? 435 HOH D O   1 
HETATM 7969 O O   . HOH H 2 .   ? -8.606  -8.215  -74.693 1.00 37.24 ? 436 HOH D O   1 
HETATM 7970 O O   . HOH H 2 .   ? -24.947 8.802   -74.069 1.00 44.51 ? 437 HOH D O   1 
HETATM 7971 O O   . HOH H 2 .   ? -20.553 20.539  -46.418 1.00 46.16 ? 438 HOH D O   1 
HETATM 7972 O O   . HOH H 2 .   ? -13.841 -5.623  -71.163 1.00 15.38 ? 439 HOH D O   1 
HETATM 7973 O O   . HOH H 2 .   ? -32.240 15.446  -66.158 1.00 46.24 ? 440 HOH D O   1 
HETATM 7974 O O   . HOH H 2 .   ? -28.282 14.455  -69.699 1.00 37.97 ? 441 HOH D O   1 
HETATM 7975 O O   . HOH H 2 .   ? -20.572 9.500   -70.609 1.00 24.25 ? 442 HOH D O   1 
HETATM 7976 O O   . HOH H 2 .   ? -30.833 8.757   -61.982 1.00 35.71 ? 443 HOH D O   1 
HETATM 7977 O O   . HOH H 2 .   ? -24.317 -11.075 -53.851 1.00 42.64 ? 444 HOH D O   1 
HETATM 7978 O O   . HOH H 2 .   ? -2.010  -9.501  -48.525 1.00 16.27 ? 445 HOH D O   1 
HETATM 7979 O O   . HOH H 2 .   ? -3.150  -4.557  -68.536 1.00 12.78 ? 446 HOH D O   1 
HETATM 7980 O O   . HOH H 2 .   ? -35.555 9.530   -62.984 1.00 53.30 ? 447 HOH D O   1 
HETATM 7981 O O   . HOH H 2 .   ? -3.660  0.712   -42.278 1.00 42.98 ? 448 HOH D O   1 
HETATM 7982 O O   . HOH H 2 .   ? 1.594   6.894   -53.221 1.00 32.28 ? 449 HOH D O   1 
HETATM 7983 O O   . HOH H 2 .   ? -21.230 -8.317  -53.218 1.00 23.49 ? 450 HOH D O   1 
HETATM 7984 O O   . HOH H 2 .   ? 4.885   -16.342 -58.548 1.00 34.38 ? 451 HOH D O   1 
HETATM 7985 O O   . HOH H 2 .   ? -6.122  12.239  -52.120 1.00 30.26 ? 452 HOH D O   1 
HETATM 7986 O O   . HOH H 2 .   ? 11.498  -1.869  -56.392 1.00 25.80 ? 453 HOH D O   1 
HETATM 7987 O O   . HOH H 2 .   ? 2.834   -6.037  -69.996 1.00 35.07 ? 454 HOH D O   1 
HETATM 7988 O O   . HOH H 2 .   ? -27.183 22.078  -56.566 1.00 29.97 ? 455 HOH D O   1 
HETATM 7989 O O   . HOH H 2 .   ? -20.239 22.824  -58.207 1.00 42.16 ? 456 HOH D O   1 
HETATM 7990 O O   . HOH H 2 .   ? 8.725   5.552   -50.949 1.00 36.67 ? 457 HOH D O   1 
HETATM 7991 O O   . HOH H 2 .   ? -9.186  -17.434 -56.794 1.00 36.50 ? 458 HOH D O   1 
HETATM 7992 O O   . HOH H 2 .   ? 4.484   3.655   -72.020 1.00 35.82 ? 459 HOH D O   1 
HETATM 7993 O O   . HOH H 2 .   ? -21.533 20.887  -66.212 1.00 36.59 ? 460 HOH D O   1 
HETATM 7994 O O   . HOH H 2 .   ? -36.926 3.263   -50.121 1.00 53.67 ? 461 HOH D O   1 
HETATM 7995 O O   . HOH H 2 .   ? 0.530   -18.953 -67.943 1.00 27.42 ? 462 HOH D O   1 
HETATM 7996 O O   . HOH H 2 .   ? -13.098 10.133  -72.943 1.00 31.05 ? 463 HOH D O   1 
HETATM 7997 O O   . HOH H 2 .   ? 8.317   -4.017  -51.735 1.00 34.61 ? 464 HOH D O   1 
HETATM 7998 O O   . HOH H 2 .   ? -22.088 17.390  -46.768 1.00 42.85 ? 465 HOH D O   1 
HETATM 7999 O O   . HOH H 2 .   ? -28.881 -9.661  -56.440 1.00 36.71 ? 466 HOH D O   1 
HETATM 8000 O O   . HOH H 2 .   ? -9.707  -11.719 -45.158 1.00 29.71 ? 467 HOH D O   1 
HETATM 8001 O O   . HOH H 2 .   ? -9.221  -11.986 -74.148 1.00 43.17 ? 468 HOH D O   1 
HETATM 8002 O O   . HOH H 2 .   ? -21.977 11.320  -71.533 1.00 32.39 ? 469 HOH D O   1 
HETATM 8003 O O   . HOH H 2 .   ? -16.943 23.791  -56.275 1.00 33.61 ? 470 HOH D O   1 
HETATM 8004 O O   . HOH H 2 .   ? -5.002  -17.035 -57.857 1.00 33.06 ? 471 HOH D O   1 
HETATM 8005 O O   . HOH H 2 .   ? -16.158 20.823  -46.320 1.00 36.69 ? 472 HOH D O   1 
HETATM 8006 O O   . HOH H 2 .   ? 12.515  5.135   -56.022 1.00 39.14 ? 473 HOH D O   1 
HETATM 8007 O O   . HOH H 2 .   ? -3.179  4.813   -48.522 1.00 47.64 ? 474 HOH D O   1 
HETATM 8008 O O   . HOH H 2 .   ? -8.938  -3.811  -76.175 1.00 24.23 ? 475 HOH D O   1 
HETATM 8009 O O   . HOH H 2 .   ? -21.903 -7.807  -47.996 1.00 36.37 ? 476 HOH D O   1 
HETATM 8010 O O   . HOH H 2 .   ? -15.587 17.721  -70.687 1.00 33.67 ? 477 HOH D O   1 
HETATM 8011 O O   . HOH H 2 .   ? 4.409   -7.512  -69.470 1.00 42.57 ? 478 HOH D O   1 
HETATM 8012 O O   . HOH H 2 .   ? 8.532   -13.624 -55.180 1.00 40.51 ? 479 HOH D O   1 
HETATM 8013 O O   . HOH H 2 .   ? 5.352   5.954   -74.278 1.00 40.61 ? 480 HOH D O   1 
HETATM 8014 O O   . HOH H 2 .   ? 8.125   7.859   -70.289 1.00 44.73 ? 481 HOH D O   1 
HETATM 8015 O O   . HOH H 2 .   ? -16.236 0.082   -75.393 1.00 28.64 ? 482 HOH D O   1 
HETATM 8016 O O   . HOH H 2 .   ? 10.410  2.904   -52.477 1.00 39.21 ? 483 HOH D O   1 
HETATM 8017 O O   . HOH H 2 .   ? -9.874  10.096  -76.490 1.00 35.51 ? 484 HOH D O   1 
HETATM 8018 O O   . HOH H 2 .   ? -10.421 9.364   -79.364 1.00 36.02 ? 485 HOH D O   1 
HETATM 8019 O O   . HOH H 2 .   ? 2.122   -16.193 -58.414 1.00 43.06 ? 486 HOH D O   1 
HETATM 8020 O O   . HOH H 2 .   ? -4.238  -14.478 -72.972 1.00 35.28 ? 487 HOH D O   1 
HETATM 8021 O O   . HOH H 2 .   ? -14.037 -0.133  -79.139 1.00 48.15 ? 488 HOH D O   1 
HETATM 8022 O O   . HOH H 2 .   ? -1.016  -5.726  -68.135 1.00 21.07 ? 489 HOH D O   1 
HETATM 8023 O O   . HOH H 2 .   ? -12.585 -8.857  -74.328 1.00 29.56 ? 490 HOH D O   1 
HETATM 8024 O O   . HOH H 2 .   ? -24.589 22.153  -62.536 1.00 34.20 ? 491 HOH D O   1 
HETATM 8025 O O   . HOH H 2 .   ? 0.297   -0.222  -47.228 1.00 29.54 ? 492 HOH D O   1 
HETATM 8026 O O   . HOH H 2 .   ? 4.908   7.030   -71.991 1.00 45.62 ? 493 HOH D O   1 
HETATM 8027 O O   . HOH H 2 .   ? -15.080 -2.389  -76.899 1.00 34.53 ? 494 HOH D O   1 
HETATM 8028 O O   . HOH H 2 .   ? -3.157  13.261  -77.023 1.00 45.28 ? 495 HOH D O   1 
HETATM 8029 O O   . HOH H 2 .   ? -27.161 8.465   -35.100 1.00 45.39 ? 496 HOH D O   1 
HETATM 8030 O O   . HOH H 2 .   ? -12.472 -2.261  -78.978 1.00 37.16 ? 497 HOH D O   1 
HETATM 8031 O O   . HOH H 2 .   ? -7.112  11.501  -81.599 1.00 34.72 ? 498 HOH D O   1 
HETATM 8032 O O   . HOH H 2 .   ? -1.834  -2.382  -76.722 1.00 43.15 ? 499 HOH D O   1 
HETATM 8033 O O   . HOH H 2 .   ? -12.814 8.490   -74.967 1.00 40.96 ? 500 HOH D O   1 
HETATM 8034 O O   . HOH H 2 .   ? -1.187  2.412   -46.794 1.00 33.18 ? 501 HOH D O   1 
HETATM 8035 O O   . HOH H 2 .   ? 13.019  -9.226  -57.124 1.00 28.42 ? 502 HOH D O   1 
HETATM 8036 O O   . HOH H 2 .   ? -16.783 5.121   -75.344 1.00 45.28 ? 503 HOH D O   1 
HETATM 8037 O O   . HOH H 2 .   ? -15.988 19.997  -70.681 1.00 39.58 ? 504 HOH D O   1 
HETATM 8038 O O   . HOH H 2 .   ? 7.553   -14.980 -53.557 1.00 42.10 ? 505 HOH D O   1 
HETATM 8039 O O   . HOH H 2 .   ? -12.842 11.511  -76.685 1.00 39.58 ? 506 HOH D O   1 
# 
