data_9JJ2
# 
_entry.id   9JJ2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9JJ2         pdb_00009jj2 10.2210/pdb9jj2/pdb 
WWPDB D_1300051438 ?            ?                   
EMDB  EMD-61515    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-04 ? 
2 'EM metadata'     1 0 2025-06-04 ? 
3 'Half map'        1 0 2025-06-04 1 
4 'Half map'        1 0 2025-06-04 2 
5 Image             1 0 2025-06-04 ? 
6 'Primary map'     1 0 2025-06-04 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9JJ2 
_pdbx_database_status.recvd_initial_deposition_date   2024-09-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of human ZnT3 under acidic conditions' 
_pdbx_database_related.db_id          EMD-61515 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              umeji@mol.f.u-tokyo.ac.jp 
_pdbx_contact_author.name_first         Umeharu 
_pdbx_contact_author.name_last          Ohto 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-4422-4044 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Ishida, H.'  1 ? 
'Yo, R.'      2 ? 
'Zhnag, Z.'   3 ? 
'Shimizu, T.' 4 ? 
'Ohto, U.'    5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structural basis for the zinc transporters, ZnT3 and ZnT4' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ishida, H.'  1 ? 
primary 'Yo, R.'      2 ? 
primary 'Zhang, Z.'   3 ? 
primary 'Shimizu, T.' 4 ? 
primary 'Ohto, U.'    5 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Probable proton-coupled zinc antiporter SLC30A3' 
_entity.formula_weight             43927.316 
_entity.pdbx_number_of_molecules   2 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Solute carrier family 30 member 3,Zinc transporter 3,ZnT-3' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAAC
AVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGIL
LYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVL
GDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHE
LHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQAGSIEGRIVKDYK
DDDDK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAAC
AVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGIL
LYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVL
GDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHE
LHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQAGSIEGRIVKDYK
DDDDK
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   PRO n 
1 4   SER n 
1 5   PRO n 
1 6   ALA n 
1 7   ALA n 
1 8   GLY n 
1 9   GLY n 
1 10  LEU n 
1 11  GLU n 
1 12  THR n 
1 13  THR n 
1 14  ARG n 
1 15  LEU n 
1 16  VAL n 
1 17  SER n 
1 18  PRO n 
1 19  ARG n 
1 20  ASP n 
1 21  ARG n 
1 22  GLY n 
1 23  GLY n 
1 24  ALA n 
1 25  GLY n 
1 26  GLY n 
1 27  SER n 
1 28  LEU n 
1 29  ARG n 
1 30  LEU n 
1 31  LYS n 
1 32  SER n 
1 33  LEU n 
1 34  PHE n 
1 35  THR n 
1 36  GLU n 
1 37  PRO n 
1 38  SER n 
1 39  GLU n 
1 40  PRO n 
1 41  LEU n 
1 42  PRO n 
1 43  GLU n 
1 44  GLU n 
1 45  SER n 
1 46  LYS n 
1 47  PRO n 
1 48  VAL n 
1 49  GLU n 
1 50  MET n 
1 51  PRO n 
1 52  PHE n 
1 53  HIS n 
1 54  HIS n 
1 55  CYS n 
1 56  HIS n 
1 57  ARG n 
1 58  ASP n 
1 59  PRO n 
1 60  LEU n 
1 61  PRO n 
1 62  PRO n 
1 63  PRO n 
1 64  GLY n 
1 65  LEU n 
1 66  THR n 
1 67  PRO n 
1 68  GLU n 
1 69  ARG n 
1 70  LEU n 
1 71  HIS n 
1 72  ALA n 
1 73  ARG n 
1 74  ARG n 
1 75  GLN n 
1 76  LEU n 
1 77  TYR n 
1 78  ALA n 
1 79  ALA n 
1 80  CYS n 
1 81  ALA n 
1 82  VAL n 
1 83  CYS n 
1 84  PHE n 
1 85  VAL n 
1 86  PHE n 
1 87  MET n 
1 88  ALA n 
1 89  GLY n 
1 90  GLU n 
1 91  VAL n 
1 92  VAL n 
1 93  GLY n 
1 94  GLY n 
1 95  TYR n 
1 96  LEU n 
1 97  ALA n 
1 98  HIS n 
1 99  SER n 
1 100 LEU n 
1 101 ALA n 
1 102 ILE n 
1 103 MET n 
1 104 THR n 
1 105 ASP n 
1 106 ALA n 
1 107 ALA n 
1 108 HIS n 
1 109 LEU n 
1 110 LEU n 
1 111 ALA n 
1 112 ASP n 
1 113 VAL n 
1 114 GLY n 
1 115 SER n 
1 116 MET n 
1 117 MET n 
1 118 GLY n 
1 119 SER n 
1 120 LEU n 
1 121 PHE n 
1 122 SER n 
1 123 LEU n 
1 124 TRP n 
1 125 LEU n 
1 126 SER n 
1 127 THR n 
1 128 ARG n 
1 129 PRO n 
1 130 ALA n 
1 131 THR n 
1 132 ARG n 
1 133 THR n 
1 134 MET n 
1 135 THR n 
1 136 PHE n 
1 137 GLY n 
1 138 TRP n 
1 139 HIS n 
1 140 ARG n 
1 141 SER n 
1 142 GLU n 
1 143 THR n 
1 144 LEU n 
1 145 GLY n 
1 146 ALA n 
1 147 LEU n 
1 148 ALA n 
1 149 SER n 
1 150 VAL n 
1 151 VAL n 
1 152 SER n 
1 153 LEU n 
1 154 TRP n 
1 155 MET n 
1 156 VAL n 
1 157 THR n 
1 158 GLY n 
1 159 ILE n 
1 160 LEU n 
1 161 LEU n 
1 162 TYR n 
1 163 LEU n 
1 164 ALA n 
1 165 PHE n 
1 166 VAL n 
1 167 ARG n 
1 168 LEU n 
1 169 LEU n 
1 170 HIS n 
1 171 SER n 
1 172 ASP n 
1 173 TYR n 
1 174 HIS n 
1 175 ILE n 
1 176 GLU n 
1 177 GLY n 
1 178 GLY n 
1 179 ALA n 
1 180 MET n 
1 181 LEU n 
1 182 LEU n 
1 183 THR n 
1 184 ALA n 
1 185 SER n 
1 186 ILE n 
1 187 ALA n 
1 188 VAL n 
1 189 CYS n 
1 190 ALA n 
1 191 ASN n 
1 192 LEU n 
1 193 LEU n 
1 194 MET n 
1 195 ALA n 
1 196 PHE n 
1 197 VAL n 
1 198 LEU n 
1 199 HIS n 
1 200 GLN n 
1 201 ALA n 
1 202 GLY n 
1 203 PRO n 
1 204 PRO n 
1 205 HIS n 
1 206 SER n 
1 207 HIS n 
1 208 GLY n 
1 209 SER n 
1 210 ARG n 
1 211 GLY n 
1 212 ALA n 
1 213 GLU n 
1 214 TYR n 
1 215 ALA n 
1 216 PRO n 
1 217 LEU n 
1 218 GLU n 
1 219 GLU n 
1 220 GLY n 
1 221 PRO n 
1 222 GLU n 
1 223 GLU n 
1 224 PRO n 
1 225 LEU n 
1 226 PRO n 
1 227 LEU n 
1 228 GLY n 
1 229 ASN n 
1 230 THR n 
1 231 SER n 
1 232 VAL n 
1 233 ARG n 
1 234 ALA n 
1 235 ALA n 
1 236 PHE n 
1 237 VAL n 
1 238 HIS n 
1 239 VAL n 
1 240 LEU n 
1 241 GLY n 
1 242 ASP n 
1 243 LEU n 
1 244 LEU n 
1 245 GLN n 
1 246 SER n 
1 247 PHE n 
1 248 GLY n 
1 249 VAL n 
1 250 LEU n 
1 251 ALA n 
1 252 ALA n 
1 253 SER n 
1 254 ILE n 
1 255 LEU n 
1 256 ILE n 
1 257 TYR n 
1 258 PHE n 
1 259 LYS n 
1 260 PRO n 
1 261 GLN n 
1 262 TYR n 
1 263 LYS n 
1 264 ALA n 
1 265 ALA n 
1 266 ASP n 
1 267 PRO n 
1 268 ILE n 
1 269 SER n 
1 270 THR n 
1 271 PHE n 
1 272 LEU n 
1 273 PHE n 
1 274 SER n 
1 275 ILE n 
1 276 CYS n 
1 277 ALA n 
1 278 LEU n 
1 279 GLY n 
1 280 SER n 
1 281 THR n 
1 282 ALA n 
1 283 PRO n 
1 284 THR n 
1 285 LEU n 
1 286 ARG n 
1 287 ASP n 
1 288 VAL n 
1 289 LEU n 
1 290 ARG n 
1 291 ILE n 
1 292 LEU n 
1 293 MET n 
1 294 GLU n 
1 295 GLY n 
1 296 THR n 
1 297 PRO n 
1 298 ARG n 
1 299 ASN n 
1 300 VAL n 
1 301 GLY n 
1 302 PHE n 
1 303 GLU n 
1 304 PRO n 
1 305 VAL n 
1 306 ARG n 
1 307 ASP n 
1 308 THR n 
1 309 LEU n 
1 310 LEU n 
1 311 SER n 
1 312 VAL n 
1 313 PRO n 
1 314 GLY n 
1 315 VAL n 
1 316 ARG n 
1 317 ALA n 
1 318 THR n 
1 319 HIS n 
1 320 GLU n 
1 321 LEU n 
1 322 HIS n 
1 323 LEU n 
1 324 TRP n 
1 325 ALA n 
1 326 LEU n 
1 327 THR n 
1 328 LEU n 
1 329 THR n 
1 330 TYR n 
1 331 HIS n 
1 332 VAL n 
1 333 ALA n 
1 334 SER n 
1 335 ALA n 
1 336 HIS n 
1 337 LEU n 
1 338 ALA n 
1 339 ILE n 
1 340 ASP n 
1 341 SER n 
1 342 THR n 
1 343 ALA n 
1 344 ASP n 
1 345 PRO n 
1 346 GLU n 
1 347 ALA n 
1 348 VAL n 
1 349 LEU n 
1 350 ALA n 
1 351 GLU n 
1 352 ALA n 
1 353 SER n 
1 354 SER n 
1 355 ARG n 
1 356 LEU n 
1 357 TYR n 
1 358 SER n 
1 359 ARG n 
1 360 PHE n 
1 361 GLY n 
1 362 PHE n 
1 363 SER n 
1 364 SER n 
1 365 CYS n 
1 366 THR n 
1 367 LEU n 
1 368 GLN n 
1 369 VAL n 
1 370 GLU n 
1 371 GLN n 
1 372 TYR n 
1 373 GLN n 
1 374 PRO n 
1 375 GLU n 
1 376 MET n 
1 377 ALA n 
1 378 GLN n 
1 379 CYS n 
1 380 LEU n 
1 381 ARG n 
1 382 CYS n 
1 383 GLN n 
1 384 GLU n 
1 385 PRO n 
1 386 PRO n 
1 387 GLN n 
1 388 ALA n 
1 389 GLY n 
1 390 SER n 
1 391 ILE n 
1 392 GLU n 
1 393 GLY n 
1 394 ARG n 
1 395 ILE n 
1 396 VAL n 
1 397 LYS n 
1 398 ASP n 
1 399 TYR n 
1 400 LYS n 
1 401 ASP n 
1 402 ASP n 
1 403 ASP n 
1 404 ASP n 
1 405 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   405 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'SLC30A3, ZNT3' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLU 2   2   ?   ?   ?   A . n 
A 1 3   PRO 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   ?   ?   ?   A . n 
A 1 5   PRO 5   5   ?   ?   ?   A . n 
A 1 6   ALA 6   6   ?   ?   ?   A . n 
A 1 7   ALA 7   7   ?   ?   ?   A . n 
A 1 8   GLY 8   8   ?   ?   ?   A . n 
A 1 9   GLY 9   9   ?   ?   ?   A . n 
A 1 10  LEU 10  10  ?   ?   ?   A . n 
A 1 11  GLU 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  ?   ?   ?   A . n 
A 1 13  THR 13  13  ?   ?   ?   A . n 
A 1 14  ARG 14  14  ?   ?   ?   A . n 
A 1 15  LEU 15  15  ?   ?   ?   A . n 
A 1 16  VAL 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  PRO 18  18  ?   ?   ?   A . n 
A 1 19  ARG 19  19  ?   ?   ?   A . n 
A 1 20  ASP 20  20  ?   ?   ?   A . n 
A 1 21  ARG 21  21  ?   ?   ?   A . n 
A 1 22  GLY 22  22  ?   ?   ?   A . n 
A 1 23  GLY 23  23  ?   ?   ?   A . n 
A 1 24  ALA 24  24  ?   ?   ?   A . n 
A 1 25  GLY 25  25  ?   ?   ?   A . n 
A 1 26  GLY 26  26  ?   ?   ?   A . n 
A 1 27  SER 27  27  ?   ?   ?   A . n 
A 1 28  LEU 28  28  ?   ?   ?   A . n 
A 1 29  ARG 29  29  ?   ?   ?   A . n 
A 1 30  LEU 30  30  ?   ?   ?   A . n 
A 1 31  LYS 31  31  ?   ?   ?   A . n 
A 1 32  SER 32  32  ?   ?   ?   A . n 
A 1 33  LEU 33  33  ?   ?   ?   A . n 
A 1 34  PHE 34  34  ?   ?   ?   A . n 
A 1 35  THR 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  PRO 37  37  ?   ?   ?   A . n 
A 1 38  SER 38  38  ?   ?   ?   A . n 
A 1 39  GLU 39  39  ?   ?   ?   A . n 
A 1 40  PRO 40  40  ?   ?   ?   A . n 
A 1 41  LEU 41  41  ?   ?   ?   A . n 
A 1 42  PRO 42  42  ?   ?   ?   A . n 
A 1 43  GLU 43  43  ?   ?   ?   A . n 
A 1 44  GLU 44  44  ?   ?   ?   A . n 
A 1 45  SER 45  45  ?   ?   ?   A . n 
A 1 46  LYS 46  46  ?   ?   ?   A . n 
A 1 47  PRO 47  47  ?   ?   ?   A . n 
A 1 48  VAL 48  48  ?   ?   ?   A . n 
A 1 49  GLU 49  49  ?   ?   ?   A . n 
A 1 50  MET 50  50  ?   ?   ?   A . n 
A 1 51  PRO 51  51  ?   ?   ?   A . n 
A 1 52  PHE 52  52  ?   ?   ?   A . n 
A 1 53  HIS 53  53  ?   ?   ?   A . n 
A 1 54  HIS 54  54  ?   ?   ?   A . n 
A 1 55  CYS 55  55  ?   ?   ?   A . n 
A 1 56  HIS 56  56  ?   ?   ?   A . n 
A 1 57  ARG 57  57  ?   ?   ?   A . n 
A 1 58  ASP 58  58  ?   ?   ?   A . n 
A 1 59  PRO 59  59  ?   ?   ?   A . n 
A 1 60  LEU 60  60  ?   ?   ?   A . n 
A 1 61  PRO 61  61  ?   ?   ?   A . n 
A 1 62  PRO 62  62  ?   ?   ?   A . n 
A 1 63  PRO 63  63  ?   ?   ?   A . n 
A 1 64  GLY 64  64  ?   ?   ?   A . n 
A 1 65  LEU 65  65  ?   ?   ?   A . n 
A 1 66  THR 66  66  ?   ?   ?   A . n 
A 1 67  PRO 67  67  ?   ?   ?   A . n 
A 1 68  GLU 68  68  ?   ?   ?   A . n 
A 1 69  ARG 69  69  ?   ?   ?   A . n 
A 1 70  LEU 70  70  ?   ?   ?   A . n 
A 1 71  HIS 71  71  ?   ?   ?   A . n 
A 1 72  ALA 72  72  ?   ?   ?   A . n 
A 1 73  ARG 73  73  ?   ?   ?   A . n 
A 1 74  ARG 74  74  ?   ?   ?   A . n 
A 1 75  GLN 75  75  ?   ?   ?   A . n 
A 1 76  LEU 76  76  ?   ?   ?   A . n 
A 1 77  TYR 77  77  ?   ?   ?   A . n 
A 1 78  ALA 78  78  78  ALA ALA A . n 
A 1 79  ALA 79  79  79  ALA ALA A . n 
A 1 80  CYS 80  80  80  CYS CYS A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  VAL 82  82  82  VAL VAL A . n 
A 1 83  CYS 83  83  83  CYS CYS A . n 
A 1 84  PHE 84  84  84  PHE PHE A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  PHE 86  86  86  PHE PHE A . n 
A 1 87  MET 87  87  87  MET MET A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  TYR 95  95  95  TYR TYR A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  HIS 98  98  98  HIS HIS A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 ALA 101 101 101 ALA ALA A . n 
A 1 102 ILE 102 102 102 ILE ILE A . n 
A 1 103 MET 103 103 103 MET MET A . n 
A 1 104 THR 104 104 104 THR THR A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 ALA 106 106 106 ALA ALA A . n 
A 1 107 ALA 107 107 107 ALA ALA A . n 
A 1 108 HIS 108 108 108 HIS HIS A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 ASP 112 112 112 ASP ASP A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 MET 116 116 116 MET MET A . n 
A 1 117 MET 117 117 117 MET MET A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 SER 119 119 119 SER SER A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 PHE 121 121 121 PHE PHE A . n 
A 1 122 SER 122 122 122 SER SER A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 TRP 124 124 124 TRP TRP A . n 
A 1 125 LEU 125 125 125 LEU LEU A . n 
A 1 126 SER 126 126 126 SER SER A . n 
A 1 127 THR 127 127 127 THR THR A . n 
A 1 128 ARG 128 128 128 ARG ARG A . n 
A 1 129 PRO 129 129 129 PRO PRO A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 THR 131 131 131 THR THR A . n 
A 1 132 ARG 132 132 132 ARG ARG A . n 
A 1 133 THR 133 133 133 THR THR A . n 
A 1 134 MET 134 134 134 MET MET A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 PHE 136 136 136 PHE PHE A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 TRP 138 138 138 TRP TRP A . n 
A 1 139 HIS 139 139 139 HIS HIS A . n 
A 1 140 ARG 140 140 140 ARG ARG A . n 
A 1 141 SER 141 141 141 SER SER A . n 
A 1 142 GLU 142 142 142 GLU GLU A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 SER 149 149 149 SER SER A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 SER 152 152 152 SER SER A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 TRP 154 154 154 TRP TRP A . n 
A 1 155 MET 155 155 155 MET MET A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 THR 157 157 157 THR THR A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 ILE 159 159 159 ILE ILE A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 TYR 162 162 162 TYR TYR A . n 
A 1 163 LEU 163 163 163 LEU LEU A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 ARG 167 167 167 ARG ARG A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 LEU 169 169 169 LEU LEU A . n 
A 1 170 HIS 170 170 170 HIS HIS A . n 
A 1 171 SER 171 171 171 SER SER A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 TYR 173 173 173 TYR TYR A . n 
A 1 174 HIS 174 174 174 HIS HIS A . n 
A 1 175 ILE 175 175 175 ILE ILE A . n 
A 1 176 GLU 176 176 176 GLU GLU A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 MET 180 180 180 MET MET A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 THR 183 183 183 THR THR A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 ILE 186 186 186 ILE ILE A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 CYS 189 189 189 CYS CYS A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 ASN 191 191 191 ASN ASN A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 LEU 193 193 193 LEU LEU A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 ALA 195 195 195 ALA ALA A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 VAL 197 197 197 VAL VAL A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 HIS 199 199 199 HIS HIS A . n 
A 1 200 GLN 200 200 ?   ?   ?   A . n 
A 1 201 ALA 201 201 ?   ?   ?   A . n 
A 1 202 GLY 202 202 ?   ?   ?   A . n 
A 1 203 PRO 203 203 ?   ?   ?   A . n 
A 1 204 PRO 204 204 ?   ?   ?   A . n 
A 1 205 HIS 205 205 ?   ?   ?   A . n 
A 1 206 SER 206 206 ?   ?   ?   A . n 
A 1 207 HIS 207 207 ?   ?   ?   A . n 
A 1 208 GLY 208 208 ?   ?   ?   A . n 
A 1 209 SER 209 209 ?   ?   ?   A . n 
A 1 210 ARG 210 210 ?   ?   ?   A . n 
A 1 211 GLY 211 211 ?   ?   ?   A . n 
A 1 212 ALA 212 212 ?   ?   ?   A . n 
A 1 213 GLU 213 213 ?   ?   ?   A . n 
A 1 214 TYR 214 214 ?   ?   ?   A . n 
A 1 215 ALA 215 215 ?   ?   ?   A . n 
A 1 216 PRO 216 216 ?   ?   ?   A . n 
A 1 217 LEU 217 217 ?   ?   ?   A . n 
A 1 218 GLU 218 218 ?   ?   ?   A . n 
A 1 219 GLU 219 219 ?   ?   ?   A . n 
A 1 220 GLY 220 220 ?   ?   ?   A . n 
A 1 221 PRO 221 221 ?   ?   ?   A . n 
A 1 222 GLU 222 222 ?   ?   ?   A . n 
A 1 223 GLU 223 223 ?   ?   ?   A . n 
A 1 224 PRO 224 224 ?   ?   ?   A . n 
A 1 225 LEU 225 225 ?   ?   ?   A . n 
A 1 226 PRO 226 226 ?   ?   ?   A . n 
A 1 227 LEU 227 227 ?   ?   ?   A . n 
A 1 228 GLY 228 228 ?   ?   ?   A . n 
A 1 229 ASN 229 229 ?   ?   ?   A . n 
A 1 230 THR 230 230 ?   ?   ?   A . n 
A 1 231 SER 231 231 ?   ?   ?   A . n 
A 1 232 VAL 232 232 ?   ?   ?   A . n 
A 1 233 ARG 233 233 ?   ?   ?   A . n 
A 1 234 ALA 234 234 ?   ?   ?   A . n 
A 1 235 ALA 235 235 ?   ?   ?   A . n 
A 1 236 PHE 236 236 ?   ?   ?   A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 HIS 238 238 238 HIS HIS A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 GLN 245 245 245 GLN GLN A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 PHE 247 247 247 PHE PHE A . n 
A 1 248 GLY 248 248 248 GLY GLY A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 ILE 254 254 254 ILE ILE A . n 
A 1 255 LEU 255 255 255 LEU LEU A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 TYR 257 257 257 TYR TYR A . n 
A 1 258 PHE 258 258 258 PHE PHE A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 PRO 260 260 260 PRO PRO A . n 
A 1 261 GLN 261 261 261 GLN GLN A . n 
A 1 262 TYR 262 262 262 TYR TYR A . n 
A 1 263 LYS 263 263 263 LYS LYS A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 ASP 266 266 266 ASP ASP A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 ILE 268 268 268 ILE ILE A . n 
A 1 269 SER 269 269 269 SER SER A . n 
A 1 270 THR 270 270 270 THR THR A . n 
A 1 271 PHE 271 271 271 PHE PHE A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 PHE 273 273 273 PHE PHE A . n 
A 1 274 SER 274 274 274 SER SER A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 CYS 276 276 276 CYS CYS A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 GLY 279 279 279 GLY GLY A . n 
A 1 280 SER 280 280 280 SER SER A . n 
A 1 281 THR 281 281 281 THR THR A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 PRO 283 283 283 PRO PRO A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 ARG 286 286 286 ARG ARG A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 ARG 290 290 290 ARG ARG A . n 
A 1 291 ILE 291 291 291 ILE ILE A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 MET 293 293 293 MET MET A . n 
A 1 294 GLU 294 294 294 GLU GLU A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 PRO 297 297 297 PRO PRO A . n 
A 1 298 ARG 298 298 298 ARG ARG A . n 
A 1 299 ASN 299 299 299 ASN ASN A . n 
A 1 300 VAL 300 300 300 VAL VAL A . n 
A 1 301 GLY 301 301 301 GLY GLY A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 GLU 303 303 303 GLU GLU A . n 
A 1 304 PRO 304 304 304 PRO PRO A . n 
A 1 305 VAL 305 305 305 VAL VAL A . n 
A 1 306 ARG 306 306 306 ARG ARG A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 THR 308 308 308 THR THR A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 PRO 313 313 313 PRO PRO A . n 
A 1 314 GLY 314 314 314 GLY GLY A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 ARG 316 316 316 ARG ARG A . n 
A 1 317 ALA 317 317 317 ALA ALA A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 HIS 319 319 319 HIS HIS A . n 
A 1 320 GLU 320 320 320 GLU GLU A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 HIS 322 322 322 HIS HIS A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 TRP 324 324 324 TRP TRP A . n 
A 1 325 ALA 325 325 325 ALA ALA A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 THR 327 327 327 THR THR A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 TYR 330 330 330 TYR TYR A . n 
A 1 331 HIS 331 331 331 HIS HIS A . n 
A 1 332 VAL 332 332 332 VAL VAL A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 SER 334 334 334 SER SER A . n 
A 1 335 ALA 335 335 335 ALA ALA A . n 
A 1 336 HIS 336 336 336 HIS HIS A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 ALA 338 338 338 ALA ALA A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 ASP 340 340 340 ASP ASP A . n 
A 1 341 SER 341 341 341 SER SER A . n 
A 1 342 THR 342 342 342 THR THR A . n 
A 1 343 ALA 343 343 343 ALA ALA A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 PRO 345 345 345 PRO PRO A . n 
A 1 346 GLU 346 346 346 GLU GLU A . n 
A 1 347 ALA 347 347 347 ALA ALA A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 LEU 349 349 349 LEU LEU A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 GLU 351 351 351 GLU GLU A . n 
A 1 352 ALA 352 352 352 ALA ALA A . n 
A 1 353 SER 353 353 353 SER SER A . n 
A 1 354 SER 354 354 354 SER SER A . n 
A 1 355 ARG 355 355 355 ARG ARG A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 TYR 357 357 357 TYR TYR A . n 
A 1 358 SER 358 358 358 SER SER A . n 
A 1 359 ARG 359 359 359 ARG ARG A . n 
A 1 360 PHE 360 360 360 PHE PHE A . n 
A 1 361 GLY 361 361 361 GLY GLY A . n 
A 1 362 PHE 362 362 362 PHE PHE A . n 
A 1 363 SER 363 363 363 SER SER A . n 
A 1 364 SER 364 364 364 SER SER A . n 
A 1 365 CYS 365 365 365 CYS CYS A . n 
A 1 366 THR 366 366 366 THR THR A . n 
A 1 367 LEU 367 367 367 LEU LEU A . n 
A 1 368 GLN 368 368 368 GLN GLN A . n 
A 1 369 VAL 369 369 369 VAL VAL A . n 
A 1 370 GLU 370 370 370 GLU GLU A . n 
A 1 371 GLN 371 371 371 GLN GLN A . n 
A 1 372 TYR 372 372 372 TYR TYR A . n 
A 1 373 GLN 373 373 ?   ?   ?   A . n 
A 1 374 PRO 374 374 ?   ?   ?   A . n 
A 1 375 GLU 375 375 ?   ?   ?   A . n 
A 1 376 MET 376 376 ?   ?   ?   A . n 
A 1 377 ALA 377 377 ?   ?   ?   A . n 
A 1 378 GLN 378 378 ?   ?   ?   A . n 
A 1 379 CYS 379 379 ?   ?   ?   A . n 
A 1 380 LEU 380 380 ?   ?   ?   A . n 
A 1 381 ARG 381 381 ?   ?   ?   A . n 
A 1 382 CYS 382 382 ?   ?   ?   A . n 
A 1 383 GLN 383 383 ?   ?   ?   A . n 
A 1 384 GLU 384 384 ?   ?   ?   A . n 
A 1 385 PRO 385 385 ?   ?   ?   A . n 
A 1 386 PRO 386 386 ?   ?   ?   A . n 
A 1 387 GLN 387 387 ?   ?   ?   A . n 
A 1 388 ALA 388 388 ?   ?   ?   A . n 
A 1 389 GLY 389 389 ?   ?   ?   A . n 
A 1 390 SER 390 390 ?   ?   ?   A . n 
A 1 391 ILE 391 391 ?   ?   ?   A . n 
A 1 392 GLU 392 392 ?   ?   ?   A . n 
A 1 393 GLY 393 393 ?   ?   ?   A . n 
A 1 394 ARG 394 394 ?   ?   ?   A . n 
A 1 395 ILE 395 395 ?   ?   ?   A . n 
A 1 396 VAL 396 396 ?   ?   ?   A . n 
A 1 397 LYS 397 397 ?   ?   ?   A . n 
A 1 398 ASP 398 398 ?   ?   ?   A . n 
A 1 399 TYR 399 399 ?   ?   ?   A . n 
A 1 400 LYS 400 400 ?   ?   ?   A . n 
A 1 401 ASP 401 401 ?   ?   ?   A . n 
A 1 402 ASP 402 402 ?   ?   ?   A . n 
A 1 403 ASP 403 403 ?   ?   ?   A . n 
A 1 404 ASP 404 404 ?   ?   ?   A . n 
A 1 405 LYS 405 405 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   GLU 2   2   ?   ?   ?   B . n 
B 1 3   PRO 3   3   ?   ?   ?   B . n 
B 1 4   SER 4   4   ?   ?   ?   B . n 
B 1 5   PRO 5   5   ?   ?   ?   B . n 
B 1 6   ALA 6   6   ?   ?   ?   B . n 
B 1 7   ALA 7   7   ?   ?   ?   B . n 
B 1 8   GLY 8   8   ?   ?   ?   B . n 
B 1 9   GLY 9   9   ?   ?   ?   B . n 
B 1 10  LEU 10  10  ?   ?   ?   B . n 
B 1 11  GLU 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  ?   ?   ?   B . n 
B 1 13  THR 13  13  ?   ?   ?   B . n 
B 1 14  ARG 14  14  ?   ?   ?   B . n 
B 1 15  LEU 15  15  ?   ?   ?   B . n 
B 1 16  VAL 16  16  ?   ?   ?   B . n 
B 1 17  SER 17  17  ?   ?   ?   B . n 
B 1 18  PRO 18  18  ?   ?   ?   B . n 
B 1 19  ARG 19  19  ?   ?   ?   B . n 
B 1 20  ASP 20  20  ?   ?   ?   B . n 
B 1 21  ARG 21  21  ?   ?   ?   B . n 
B 1 22  GLY 22  22  ?   ?   ?   B . n 
B 1 23  GLY 23  23  ?   ?   ?   B . n 
B 1 24  ALA 24  24  ?   ?   ?   B . n 
B 1 25  GLY 25  25  ?   ?   ?   B . n 
B 1 26  GLY 26  26  ?   ?   ?   B . n 
B 1 27  SER 27  27  ?   ?   ?   B . n 
B 1 28  LEU 28  28  ?   ?   ?   B . n 
B 1 29  ARG 29  29  ?   ?   ?   B . n 
B 1 30  LEU 30  30  ?   ?   ?   B . n 
B 1 31  LYS 31  31  ?   ?   ?   B . n 
B 1 32  SER 32  32  ?   ?   ?   B . n 
B 1 33  LEU 33  33  ?   ?   ?   B . n 
B 1 34  PHE 34  34  ?   ?   ?   B . n 
B 1 35  THR 35  35  ?   ?   ?   B . n 
B 1 36  GLU 36  36  ?   ?   ?   B . n 
B 1 37  PRO 37  37  ?   ?   ?   B . n 
B 1 38  SER 38  38  ?   ?   ?   B . n 
B 1 39  GLU 39  39  ?   ?   ?   B . n 
B 1 40  PRO 40  40  ?   ?   ?   B . n 
B 1 41  LEU 41  41  ?   ?   ?   B . n 
B 1 42  PRO 42  42  ?   ?   ?   B . n 
B 1 43  GLU 43  43  ?   ?   ?   B . n 
B 1 44  GLU 44  44  ?   ?   ?   B . n 
B 1 45  SER 45  45  ?   ?   ?   B . n 
B 1 46  LYS 46  46  ?   ?   ?   B . n 
B 1 47  PRO 47  47  ?   ?   ?   B . n 
B 1 48  VAL 48  48  ?   ?   ?   B . n 
B 1 49  GLU 49  49  ?   ?   ?   B . n 
B 1 50  MET 50  50  ?   ?   ?   B . n 
B 1 51  PRO 51  51  ?   ?   ?   B . n 
B 1 52  PHE 52  52  ?   ?   ?   B . n 
B 1 53  HIS 53  53  ?   ?   ?   B . n 
B 1 54  HIS 54  54  ?   ?   ?   B . n 
B 1 55  CYS 55  55  ?   ?   ?   B . n 
B 1 56  HIS 56  56  ?   ?   ?   B . n 
B 1 57  ARG 57  57  ?   ?   ?   B . n 
B 1 58  ASP 58  58  ?   ?   ?   B . n 
B 1 59  PRO 59  59  ?   ?   ?   B . n 
B 1 60  LEU 60  60  ?   ?   ?   B . n 
B 1 61  PRO 61  61  ?   ?   ?   B . n 
B 1 62  PRO 62  62  ?   ?   ?   B . n 
B 1 63  PRO 63  63  ?   ?   ?   B . n 
B 1 64  GLY 64  64  ?   ?   ?   B . n 
B 1 65  LEU 65  65  ?   ?   ?   B . n 
B 1 66  THR 66  66  ?   ?   ?   B . n 
B 1 67  PRO 67  67  ?   ?   ?   B . n 
B 1 68  GLU 68  68  ?   ?   ?   B . n 
B 1 69  ARG 69  69  ?   ?   ?   B . n 
B 1 70  LEU 70  70  ?   ?   ?   B . n 
B 1 71  HIS 71  71  ?   ?   ?   B . n 
B 1 72  ALA 72  72  ?   ?   ?   B . n 
B 1 73  ARG 73  73  ?   ?   ?   B . n 
B 1 74  ARG 74  74  ?   ?   ?   B . n 
B 1 75  GLN 75  75  ?   ?   ?   B . n 
B 1 76  LEU 76  76  ?   ?   ?   B . n 
B 1 77  TYR 77  77  ?   ?   ?   B . n 
B 1 78  ALA 78  78  78  ALA ALA B . n 
B 1 79  ALA 79  79  79  ALA ALA B . n 
B 1 80  CYS 80  80  80  CYS CYS B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  VAL 82  82  82  VAL VAL B . n 
B 1 83  CYS 83  83  83  CYS CYS B . n 
B 1 84  PHE 84  84  84  PHE PHE B . n 
B 1 85  VAL 85  85  85  VAL VAL B . n 
B 1 86  PHE 86  86  86  PHE PHE B . n 
B 1 87  MET 87  87  87  MET MET B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  GLY 93  93  93  GLY GLY B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  TYR 95  95  95  TYR TYR B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  ALA 97  97  97  ALA ALA B . n 
B 1 98  HIS 98  98  98  HIS HIS B . n 
B 1 99  SER 99  99  99  SER SER B . n 
B 1 100 LEU 100 100 100 LEU LEU B . n 
B 1 101 ALA 101 101 101 ALA ALA B . n 
B 1 102 ILE 102 102 102 ILE ILE B . n 
B 1 103 MET 103 103 103 MET MET B . n 
B 1 104 THR 104 104 104 THR THR B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 ALA 106 106 106 ALA ALA B . n 
B 1 107 ALA 107 107 107 ALA ALA B . n 
B 1 108 HIS 108 108 108 HIS HIS B . n 
B 1 109 LEU 109 109 109 LEU LEU B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 ALA 111 111 111 ALA ALA B . n 
B 1 112 ASP 112 112 112 ASP ASP B . n 
B 1 113 VAL 113 113 113 VAL VAL B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 SER 115 115 115 SER SER B . n 
B 1 116 MET 116 116 116 MET MET B . n 
B 1 117 MET 117 117 117 MET MET B . n 
B 1 118 GLY 118 118 118 GLY GLY B . n 
B 1 119 SER 119 119 119 SER SER B . n 
B 1 120 LEU 120 120 120 LEU LEU B . n 
B 1 121 PHE 121 121 121 PHE PHE B . n 
B 1 122 SER 122 122 122 SER SER B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 TRP 124 124 124 TRP TRP B . n 
B 1 125 LEU 125 125 125 LEU LEU B . n 
B 1 126 SER 126 126 126 SER SER B . n 
B 1 127 THR 127 127 127 THR THR B . n 
B 1 128 ARG 128 128 128 ARG ARG B . n 
B 1 129 PRO 129 129 129 PRO PRO B . n 
B 1 130 ALA 130 130 130 ALA ALA B . n 
B 1 131 THR 131 131 131 THR THR B . n 
B 1 132 ARG 132 132 132 ARG ARG B . n 
B 1 133 THR 133 133 133 THR THR B . n 
B 1 134 MET 134 134 134 MET MET B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 PHE 136 136 136 PHE PHE B . n 
B 1 137 GLY 137 137 137 GLY GLY B . n 
B 1 138 TRP 138 138 138 TRP TRP B . n 
B 1 139 HIS 139 139 139 HIS HIS B . n 
B 1 140 ARG 140 140 140 ARG ARG B . n 
B 1 141 SER 141 141 141 SER SER B . n 
B 1 142 GLU 142 142 142 GLU GLU B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 ALA 146 146 146 ALA ALA B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 ALA 148 148 148 ALA ALA B . n 
B 1 149 SER 149 149 149 SER SER B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 VAL 151 151 151 VAL VAL B . n 
B 1 152 SER 152 152 152 SER SER B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 TRP 154 154 154 TRP TRP B . n 
B 1 155 MET 155 155 155 MET MET B . n 
B 1 156 VAL 156 156 156 VAL VAL B . n 
B 1 157 THR 157 157 157 THR THR B . n 
B 1 158 GLY 158 158 158 GLY GLY B . n 
B 1 159 ILE 159 159 159 ILE ILE B . n 
B 1 160 LEU 160 160 160 LEU LEU B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 TYR 162 162 162 TYR TYR B . n 
B 1 163 LEU 163 163 163 LEU LEU B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 PHE 165 165 165 PHE PHE B . n 
B 1 166 VAL 166 166 166 VAL VAL B . n 
B 1 167 ARG 167 167 167 ARG ARG B . n 
B 1 168 LEU 168 168 168 LEU LEU B . n 
B 1 169 LEU 169 169 169 LEU LEU B . n 
B 1 170 HIS 170 170 170 HIS HIS B . n 
B 1 171 SER 171 171 171 SER SER B . n 
B 1 172 ASP 172 172 172 ASP ASP B . n 
B 1 173 TYR 173 173 173 TYR TYR B . n 
B 1 174 HIS 174 174 174 HIS HIS B . n 
B 1 175 ILE 175 175 175 ILE ILE B . n 
B 1 176 GLU 176 176 176 GLU GLU B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 ALA 179 179 179 ALA ALA B . n 
B 1 180 MET 180 180 180 MET MET B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 THR 183 183 183 THR THR B . n 
B 1 184 ALA 184 184 184 ALA ALA B . n 
B 1 185 SER 185 185 185 SER SER B . n 
B 1 186 ILE 186 186 186 ILE ILE B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 VAL 188 188 188 VAL VAL B . n 
B 1 189 CYS 189 189 189 CYS CYS B . n 
B 1 190 ALA 190 190 190 ALA ALA B . n 
B 1 191 ASN 191 191 191 ASN ASN B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 LEU 193 193 193 LEU LEU B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 ALA 195 195 195 ALA ALA B . n 
B 1 196 PHE 196 196 196 PHE PHE B . n 
B 1 197 VAL 197 197 197 VAL VAL B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 HIS 199 199 199 HIS HIS B . n 
B 1 200 GLN 200 200 ?   ?   ?   B . n 
B 1 201 ALA 201 201 ?   ?   ?   B . n 
B 1 202 GLY 202 202 ?   ?   ?   B . n 
B 1 203 PRO 203 203 ?   ?   ?   B . n 
B 1 204 PRO 204 204 ?   ?   ?   B . n 
B 1 205 HIS 205 205 ?   ?   ?   B . n 
B 1 206 SER 206 206 ?   ?   ?   B . n 
B 1 207 HIS 207 207 ?   ?   ?   B . n 
B 1 208 GLY 208 208 ?   ?   ?   B . n 
B 1 209 SER 209 209 ?   ?   ?   B . n 
B 1 210 ARG 210 210 ?   ?   ?   B . n 
B 1 211 GLY 211 211 ?   ?   ?   B . n 
B 1 212 ALA 212 212 ?   ?   ?   B . n 
B 1 213 GLU 213 213 ?   ?   ?   B . n 
B 1 214 TYR 214 214 ?   ?   ?   B . n 
B 1 215 ALA 215 215 ?   ?   ?   B . n 
B 1 216 PRO 216 216 ?   ?   ?   B . n 
B 1 217 LEU 217 217 ?   ?   ?   B . n 
B 1 218 GLU 218 218 ?   ?   ?   B . n 
B 1 219 GLU 219 219 ?   ?   ?   B . n 
B 1 220 GLY 220 220 ?   ?   ?   B . n 
B 1 221 PRO 221 221 ?   ?   ?   B . n 
B 1 222 GLU 222 222 ?   ?   ?   B . n 
B 1 223 GLU 223 223 ?   ?   ?   B . n 
B 1 224 PRO 224 224 ?   ?   ?   B . n 
B 1 225 LEU 225 225 ?   ?   ?   B . n 
B 1 226 PRO 226 226 ?   ?   ?   B . n 
B 1 227 LEU 227 227 ?   ?   ?   B . n 
B 1 228 GLY 228 228 ?   ?   ?   B . n 
B 1 229 ASN 229 229 ?   ?   ?   B . n 
B 1 230 THR 230 230 ?   ?   ?   B . n 
B 1 231 SER 231 231 ?   ?   ?   B . n 
B 1 232 VAL 232 232 ?   ?   ?   B . n 
B 1 233 ARG 233 233 ?   ?   ?   B . n 
B 1 234 ALA 234 234 ?   ?   ?   B . n 
B 1 235 ALA 235 235 ?   ?   ?   B . n 
B 1 236 PHE 236 236 ?   ?   ?   B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 HIS 238 238 238 HIS HIS B . n 
B 1 239 VAL 239 239 239 VAL VAL B . n 
B 1 240 LEU 240 240 240 LEU LEU B . n 
B 1 241 GLY 241 241 241 GLY GLY B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 LEU 243 243 243 LEU LEU B . n 
B 1 244 LEU 244 244 244 LEU LEU B . n 
B 1 245 GLN 245 245 245 GLN GLN B . n 
B 1 246 SER 246 246 246 SER SER B . n 
B 1 247 PHE 247 247 247 PHE PHE B . n 
B 1 248 GLY 248 248 248 GLY GLY B . n 
B 1 249 VAL 249 249 249 VAL VAL B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 ALA 251 251 251 ALA ALA B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 ILE 254 254 254 ILE ILE B . n 
B 1 255 LEU 255 255 255 LEU LEU B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 TYR 257 257 257 TYR TYR B . n 
B 1 258 PHE 258 258 258 PHE PHE B . n 
B 1 259 LYS 259 259 259 LYS LYS B . n 
B 1 260 PRO 260 260 260 PRO PRO B . n 
B 1 261 GLN 261 261 261 GLN GLN B . n 
B 1 262 TYR 262 262 262 TYR TYR B . n 
B 1 263 LYS 263 263 263 LYS LYS B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 ASP 266 266 266 ASP ASP B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 ILE 268 268 268 ILE ILE B . n 
B 1 269 SER 269 269 269 SER SER B . n 
B 1 270 THR 270 270 270 THR THR B . n 
B 1 271 PHE 271 271 271 PHE PHE B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 PHE 273 273 273 PHE PHE B . n 
B 1 274 SER 274 274 274 SER SER B . n 
B 1 275 ILE 275 275 275 ILE ILE B . n 
B 1 276 CYS 276 276 276 CYS CYS B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 GLY 279 279 279 GLY GLY B . n 
B 1 280 SER 280 280 280 SER SER B . n 
B 1 281 THR 281 281 281 THR THR B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 PRO 283 283 283 PRO PRO B . n 
B 1 284 THR 284 284 284 THR THR B . n 
B 1 285 LEU 285 285 285 LEU LEU B . n 
B 1 286 ARG 286 286 286 ARG ARG B . n 
B 1 287 ASP 287 287 287 ASP ASP B . n 
B 1 288 VAL 288 288 288 VAL VAL B . n 
B 1 289 LEU 289 289 289 LEU LEU B . n 
B 1 290 ARG 290 290 290 ARG ARG B . n 
B 1 291 ILE 291 291 291 ILE ILE B . n 
B 1 292 LEU 292 292 292 LEU LEU B . n 
B 1 293 MET 293 293 293 MET MET B . n 
B 1 294 GLU 294 294 294 GLU GLU B . n 
B 1 295 GLY 295 295 295 GLY GLY B . n 
B 1 296 THR 296 296 296 THR THR B . n 
B 1 297 PRO 297 297 297 PRO PRO B . n 
B 1 298 ARG 298 298 298 ARG ARG B . n 
B 1 299 ASN 299 299 299 ASN ASN B . n 
B 1 300 VAL 300 300 300 VAL VAL B . n 
B 1 301 GLY 301 301 301 GLY GLY B . n 
B 1 302 PHE 302 302 302 PHE PHE B . n 
B 1 303 GLU 303 303 303 GLU GLU B . n 
B 1 304 PRO 304 304 304 PRO PRO B . n 
B 1 305 VAL 305 305 305 VAL VAL B . n 
B 1 306 ARG 306 306 306 ARG ARG B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 THR 308 308 308 THR THR B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 LEU 310 310 310 LEU LEU B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 VAL 312 312 312 VAL VAL B . n 
B 1 313 PRO 313 313 313 PRO PRO B . n 
B 1 314 GLY 314 314 314 GLY GLY B . n 
B 1 315 VAL 315 315 315 VAL VAL B . n 
B 1 316 ARG 316 316 316 ARG ARG B . n 
B 1 317 ALA 317 317 317 ALA ALA B . n 
B 1 318 THR 318 318 318 THR THR B . n 
B 1 319 HIS 319 319 319 HIS HIS B . n 
B 1 320 GLU 320 320 320 GLU GLU B . n 
B 1 321 LEU 321 321 321 LEU LEU B . n 
B 1 322 HIS 322 322 322 HIS HIS B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 TRP 324 324 324 TRP TRP B . n 
B 1 325 ALA 325 325 325 ALA ALA B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 THR 327 327 327 THR THR B . n 
B 1 328 LEU 328 328 328 LEU LEU B . n 
B 1 329 THR 329 329 329 THR THR B . n 
B 1 330 TYR 330 330 330 TYR TYR B . n 
B 1 331 HIS 331 331 331 HIS HIS B . n 
B 1 332 VAL 332 332 332 VAL VAL B . n 
B 1 333 ALA 333 333 333 ALA ALA B . n 
B 1 334 SER 334 334 334 SER SER B . n 
B 1 335 ALA 335 335 335 ALA ALA B . n 
B 1 336 HIS 336 336 336 HIS HIS B . n 
B 1 337 LEU 337 337 337 LEU LEU B . n 
B 1 338 ALA 338 338 338 ALA ALA B . n 
B 1 339 ILE 339 339 339 ILE ILE B . n 
B 1 340 ASP 340 340 340 ASP ASP B . n 
B 1 341 SER 341 341 341 SER SER B . n 
B 1 342 THR 342 342 342 THR THR B . n 
B 1 343 ALA 343 343 343 ALA ALA B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 PRO 345 345 345 PRO PRO B . n 
B 1 346 GLU 346 346 346 GLU GLU B . n 
B 1 347 ALA 347 347 347 ALA ALA B . n 
B 1 348 VAL 348 348 348 VAL VAL B . n 
B 1 349 LEU 349 349 349 LEU LEU B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 GLU 351 351 351 GLU GLU B . n 
B 1 352 ALA 352 352 352 ALA ALA B . n 
B 1 353 SER 353 353 353 SER SER B . n 
B 1 354 SER 354 354 354 SER SER B . n 
B 1 355 ARG 355 355 355 ARG ARG B . n 
B 1 356 LEU 356 356 356 LEU LEU B . n 
B 1 357 TYR 357 357 357 TYR TYR B . n 
B 1 358 SER 358 358 358 SER SER B . n 
B 1 359 ARG 359 359 359 ARG ARG B . n 
B 1 360 PHE 360 360 360 PHE PHE B . n 
B 1 361 GLY 361 361 361 GLY GLY B . n 
B 1 362 PHE 362 362 362 PHE PHE B . n 
B 1 363 SER 363 363 363 SER SER B . n 
B 1 364 SER 364 364 364 SER SER B . n 
B 1 365 CYS 365 365 365 CYS CYS B . n 
B 1 366 THR 366 366 366 THR THR B . n 
B 1 367 LEU 367 367 367 LEU LEU B . n 
B 1 368 GLN 368 368 368 GLN GLN B . n 
B 1 369 VAL 369 369 369 VAL VAL B . n 
B 1 370 GLU 370 370 370 GLU GLU B . n 
B 1 371 GLN 371 371 371 GLN GLN B . n 
B 1 372 TYR 372 372 372 TYR TYR B . n 
B 1 373 GLN 373 373 ?   ?   ?   B . n 
B 1 374 PRO 374 374 ?   ?   ?   B . n 
B 1 375 GLU 375 375 ?   ?   ?   B . n 
B 1 376 MET 376 376 ?   ?   ?   B . n 
B 1 377 ALA 377 377 ?   ?   ?   B . n 
B 1 378 GLN 378 378 ?   ?   ?   B . n 
B 1 379 CYS 379 379 ?   ?   ?   B . n 
B 1 380 LEU 380 380 ?   ?   ?   B . n 
B 1 381 ARG 381 381 ?   ?   ?   B . n 
B 1 382 CYS 382 382 ?   ?   ?   B . n 
B 1 383 GLN 383 383 ?   ?   ?   B . n 
B 1 384 GLU 384 384 ?   ?   ?   B . n 
B 1 385 PRO 385 385 ?   ?   ?   B . n 
B 1 386 PRO 386 386 ?   ?   ?   B . n 
B 1 387 GLN 387 387 ?   ?   ?   B . n 
B 1 388 ALA 388 388 ?   ?   ?   B . n 
B 1 389 GLY 389 389 ?   ?   ?   B . n 
B 1 390 SER 390 390 ?   ?   ?   B . n 
B 1 391 ILE 391 391 ?   ?   ?   B . n 
B 1 392 GLU 392 392 ?   ?   ?   B . n 
B 1 393 GLY 393 393 ?   ?   ?   B . n 
B 1 394 ARG 394 394 ?   ?   ?   B . n 
B 1 395 ILE 395 395 ?   ?   ?   B . n 
B 1 396 VAL 396 396 ?   ?   ?   B . n 
B 1 397 LYS 397 397 ?   ?   ?   B . n 
B 1 398 ASP 398 398 ?   ?   ?   B . n 
B 1 399 TYR 399 399 ?   ?   ?   B . n 
B 1 400 LYS 400 400 ?   ?   ?   B . n 
B 1 401 ASP 401 401 ?   ?   ?   B . n 
B 1 402 ASP 402 402 ?   ?   ?   B . n 
B 1 403 ASP 403 403 ?   ?   ?   B . n 
B 1 404 ASP 404 404 ?   ?   ?   B . n 
B 1 405 LYS 405 405 ?   ?   ?   B . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9JJ2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9JJ2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9JJ2 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9JJ2 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 4006 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.781 ? 5461 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.898 ? 550  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043 ? 661  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 670  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9JJ2 
_struct.title                        'Cryo-EM structure of human ZnT3 under acidic conditions' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9JJ2 
_struct_keywords.text            'zinc transporter, membrane protein, ZnT, antiporter' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ZNT3_HUMAN 
_struct_ref.pdbx_db_accession          Q99726 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MEPSPAAGGLETTRLVSPRDRGGAGGSLRLKSLFTEPSEPLPEESKPVEMPFHHCHRDPLPPPGLTPERLHARRQLYAAC
AVCFVFMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFGWHRSETLGALASVVSLWMVTGIL
LYLAFVRLLHSDYHIEGGAMLLTASIAVCANLLMAFVLHQAGPPHSHGSRGAEYAPLEEGPEEPLPLGNTSVRAAFVHVL
GDLLQSFGVLAASILIYFKPQYKAADPISTFLFSICALGSTAPTLRDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHE
LHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQA
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9JJ2 A 1 ? 388 ? Q99726 1 ? 388 ? 1 388 
2 1 9JJ2 B 1 ? 388 ? Q99726 1 ? 388 ? 1 388 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9JJ2 GLY A 389 ? UNP Q99726 ? ? 'expression tag' 389 1  
1 9JJ2 SER A 390 ? UNP Q99726 ? ? 'expression tag' 390 2  
1 9JJ2 ILE A 391 ? UNP Q99726 ? ? 'expression tag' 391 3  
1 9JJ2 GLU A 392 ? UNP Q99726 ? ? 'expression tag' 392 4  
1 9JJ2 GLY A 393 ? UNP Q99726 ? ? 'expression tag' 393 5  
1 9JJ2 ARG A 394 ? UNP Q99726 ? ? 'expression tag' 394 6  
1 9JJ2 ILE A 395 ? UNP Q99726 ? ? 'expression tag' 395 7  
1 9JJ2 VAL A 396 ? UNP Q99726 ? ? 'expression tag' 396 8  
1 9JJ2 LYS A 397 ? UNP Q99726 ? ? 'expression tag' 397 9  
1 9JJ2 ASP A 398 ? UNP Q99726 ? ? 'expression tag' 398 10 
1 9JJ2 TYR A 399 ? UNP Q99726 ? ? 'expression tag' 399 11 
1 9JJ2 LYS A 400 ? UNP Q99726 ? ? 'expression tag' 400 12 
1 9JJ2 ASP A 401 ? UNP Q99726 ? ? 'expression tag' 401 13 
1 9JJ2 ASP A 402 ? UNP Q99726 ? ? 'expression tag' 402 14 
1 9JJ2 ASP A 403 ? UNP Q99726 ? ? 'expression tag' 403 15 
1 9JJ2 ASP A 404 ? UNP Q99726 ? ? 'expression tag' 404 16 
1 9JJ2 LYS A 405 ? UNP Q99726 ? ? 'expression tag' 405 17 
2 9JJ2 GLY B 389 ? UNP Q99726 ? ? 'expression tag' 389 18 
2 9JJ2 SER B 390 ? UNP Q99726 ? ? 'expression tag' 390 19 
2 9JJ2 ILE B 391 ? UNP Q99726 ? ? 'expression tag' 391 20 
2 9JJ2 GLU B 392 ? UNP Q99726 ? ? 'expression tag' 392 21 
2 9JJ2 GLY B 393 ? UNP Q99726 ? ? 'expression tag' 393 22 
2 9JJ2 ARG B 394 ? UNP Q99726 ? ? 'expression tag' 394 23 
2 9JJ2 ILE B 395 ? UNP Q99726 ? ? 'expression tag' 395 24 
2 9JJ2 VAL B 396 ? UNP Q99726 ? ? 'expression tag' 396 25 
2 9JJ2 LYS B 397 ? UNP Q99726 ? ? 'expression tag' 397 26 
2 9JJ2 ASP B 398 ? UNP Q99726 ? ? 'expression tag' 398 27 
2 9JJ2 TYR B 399 ? UNP Q99726 ? ? 'expression tag' 399 28 
2 9JJ2 LYS B 400 ? UNP Q99726 ? ? 'expression tag' 400 29 
2 9JJ2 ASP B 401 ? UNP Q99726 ? ? 'expression tag' 401 30 
2 9JJ2 ASP B 402 ? UNP Q99726 ? ? 'expression tag' 402 31 
2 9JJ2 ASP B 403 ? UNP Q99726 ? ? 'expression tag' 403 32 
2 9JJ2 ASP B 404 ? UNP Q99726 ? ? 'expression tag' 404 33 
2 9JJ2 LYS B 405 ? UNP Q99726 ? ? 'expression tag' 405 34 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 79  ? HIS A 98  ? ALA A 79  HIS A 98  1 ? 20 
HELX_P HELX_P2  AA2 LEU A 100 ? THR A 127 ? LEU A 100 THR A 127 1 ? 28 
HELX_P HELX_P3  AA3 ARG A 140 ? HIS A 170 ? ARG A 140 HIS A 170 1 ? 31 
HELX_P HELX_P4  AA4 GLU A 176 ? HIS A 199 ? GLU A 176 HIS A 199 1 ? 24 
HELX_P HELX_P5  AA5 HIS A 238 ? LYS A 259 ? HIS A 238 LYS A 259 1 ? 22 
HELX_P HELX_P6  AA6 ALA A 264 ? GLU A 294 ? ALA A 264 GLU A 294 1 ? 31 
HELX_P HELX_P7  AA7 GLY A 301 ? SER A 311 ? GLY A 301 SER A 311 1 ? 11 
HELX_P HELX_P8  AA8 ASP A 344 ? GLY A 361 ? ASP A 344 GLY A 361 1 ? 18 
HELX_P HELX_P9  AA9 ALA B 81  ? HIS B 98  ? ALA B 81  HIS B 98  1 ? 18 
HELX_P HELX_P10 AB1 LEU B 100 ? THR B 127 ? LEU B 100 THR B 127 1 ? 28 
HELX_P HELX_P11 AB2 ARG B 140 ? HIS B 170 ? ARG B 140 HIS B 170 1 ? 31 
HELX_P HELX_P12 AB3 GLU B 176 ? HIS B 199 ? GLU B 176 HIS B 199 1 ? 24 
HELX_P HELX_P13 AB4 HIS B 238 ? LYS B 259 ? HIS B 238 LYS B 259 1 ? 22 
HELX_P HELX_P14 AB5 ALA B 264 ? GLU B 294 ? ALA B 264 GLU B 294 1 ? 31 
HELX_P HELX_P15 AB6 GLY B 301 ? SER B 311 ? GLY B 301 SER B 311 1 ? 11 
HELX_P HELX_P16 AB7 ASP B 344 ? GLY B 361 ? ASP B 344 GLY B 361 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 3 ? 
AA3 ? 3 ? 
AA4 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 315 ? ALA A 317 ? VAL A 315 ALA A 317 
AA1 2 ALA A 338 ? ILE A 339 ? ALA A 338 ILE A 339 
AA1 3 GLU A 370 ? GLN A 371 ? GLU A 370 GLN A 371 
AA2 1 HIS A 322 ? ALA A 325 ? HIS A 322 ALA A 325 
AA2 2 HIS A 331 ? ALA A 335 ? HIS A 331 ALA A 335 
AA2 3 SER A 364 ? LEU A 367 ? SER A 364 LEU A 367 
AA3 1 VAL B 315 ? ALA B 317 ? VAL B 315 ALA B 317 
AA3 2 ALA B 338 ? ILE B 339 ? ALA B 338 ILE B 339 
AA3 3 GLU B 370 ? GLN B 371 ? GLU B 370 GLN B 371 
AA4 1 HIS B 322 ? ALA B 325 ? HIS B 322 ALA B 325 
AA4 2 HIS B 331 ? ALA B 335 ? HIS B 331 ALA B 335 
AA4 3 SER B 364 ? LEU B 367 ? SER B 364 LEU B 367 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG A 316 ? N ARG A 316 O ALA A 338 ? O ALA A 338 
AA1 2 3 N ILE A 339 ? N ILE A 339 O GLU A 370 ? O GLU A 370 
AA2 1 2 N TRP A 324 ? N TRP A 324 O VAL A 332 ? O VAL A 332 
AA2 2 3 N ALA A 333 ? N ALA A 333 O THR A 366 ? O THR A 366 
AA3 1 2 N ALA B 317 ? N ALA B 317 O ALA B 338 ? O ALA B 338 
AA3 2 3 N ILE B 339 ? N ILE B 339 O GLU B 370 ? O GLU B 370 
AA4 1 2 N TRP B 324 ? N TRP B 324 O VAL B 332 ? O VAL B 332 
AA4 2 3 N ALA B 333 ? N ALA B 333 O THR B 366 ? O THR B 366 
# 
_pdbx_entry_details.entry_id                   9JJ2 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 294 ? ? 70.39  45.47  
2 1 HIS A 319 ? ? -93.98 -60.20 
3 1 HIS B 319 ? ? -94.17 -60.65 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9JJ2 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9JJ2 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.0 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               279000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            5.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 ZnT3 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9JJ2 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9JJ2 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9JJ2 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLU 2   ? A GLU 2   
3   1 Y 1 A PRO 3   ? A PRO 3   
4   1 Y 1 A SER 4   ? A SER 4   
5   1 Y 1 A PRO 5   ? A PRO 5   
6   1 Y 1 A ALA 6   ? A ALA 6   
7   1 Y 1 A ALA 7   ? A ALA 7   
8   1 Y 1 A GLY 8   ? A GLY 8   
9   1 Y 1 A GLY 9   ? A GLY 9   
10  1 Y 1 A LEU 10  ? A LEU 10  
11  1 Y 1 A GLU 11  ? A GLU 11  
12  1 Y 1 A THR 12  ? A THR 12  
13  1 Y 1 A THR 13  ? A THR 13  
14  1 Y 1 A ARG 14  ? A ARG 14  
15  1 Y 1 A LEU 15  ? A LEU 15  
16  1 Y 1 A VAL 16  ? A VAL 16  
17  1 Y 1 A SER 17  ? A SER 17  
18  1 Y 1 A PRO 18  ? A PRO 18  
19  1 Y 1 A ARG 19  ? A ARG 19  
20  1 Y 1 A ASP 20  ? A ASP 20  
21  1 Y 1 A ARG 21  ? A ARG 21  
22  1 Y 1 A GLY 22  ? A GLY 22  
23  1 Y 1 A GLY 23  ? A GLY 23  
24  1 Y 1 A ALA 24  ? A ALA 24  
25  1 Y 1 A GLY 25  ? A GLY 25  
26  1 Y 1 A GLY 26  ? A GLY 26  
27  1 Y 1 A SER 27  ? A SER 27  
28  1 Y 1 A LEU 28  ? A LEU 28  
29  1 Y 1 A ARG 29  ? A ARG 29  
30  1 Y 1 A LEU 30  ? A LEU 30  
31  1 Y 1 A LYS 31  ? A LYS 31  
32  1 Y 1 A SER 32  ? A SER 32  
33  1 Y 1 A LEU 33  ? A LEU 33  
34  1 Y 1 A PHE 34  ? A PHE 34  
35  1 Y 1 A THR 35  ? A THR 35  
36  1 Y 1 A GLU 36  ? A GLU 36  
37  1 Y 1 A PRO 37  ? A PRO 37  
38  1 Y 1 A SER 38  ? A SER 38  
39  1 Y 1 A GLU 39  ? A GLU 39  
40  1 Y 1 A PRO 40  ? A PRO 40  
41  1 Y 1 A LEU 41  ? A LEU 41  
42  1 Y 1 A PRO 42  ? A PRO 42  
43  1 Y 1 A GLU 43  ? A GLU 43  
44  1 Y 1 A GLU 44  ? A GLU 44  
45  1 Y 1 A SER 45  ? A SER 45  
46  1 Y 1 A LYS 46  ? A LYS 46  
47  1 Y 1 A PRO 47  ? A PRO 47  
48  1 Y 1 A VAL 48  ? A VAL 48  
49  1 Y 1 A GLU 49  ? A GLU 49  
50  1 Y 1 A MET 50  ? A MET 50  
51  1 Y 1 A PRO 51  ? A PRO 51  
52  1 Y 1 A PHE 52  ? A PHE 52  
53  1 Y 1 A HIS 53  ? A HIS 53  
54  1 Y 1 A HIS 54  ? A HIS 54  
55  1 Y 1 A CYS 55  ? A CYS 55  
56  1 Y 1 A HIS 56  ? A HIS 56  
57  1 Y 1 A ARG 57  ? A ARG 57  
58  1 Y 1 A ASP 58  ? A ASP 58  
59  1 Y 1 A PRO 59  ? A PRO 59  
60  1 Y 1 A LEU 60  ? A LEU 60  
61  1 Y 1 A PRO 61  ? A PRO 61  
62  1 Y 1 A PRO 62  ? A PRO 62  
63  1 Y 1 A PRO 63  ? A PRO 63  
64  1 Y 1 A GLY 64  ? A GLY 64  
65  1 Y 1 A LEU 65  ? A LEU 65  
66  1 Y 1 A THR 66  ? A THR 66  
67  1 Y 1 A PRO 67  ? A PRO 67  
68  1 Y 1 A GLU 68  ? A GLU 68  
69  1 Y 1 A ARG 69  ? A ARG 69  
70  1 Y 1 A LEU 70  ? A LEU 70  
71  1 Y 1 A HIS 71  ? A HIS 71  
72  1 Y 1 A ALA 72  ? A ALA 72  
73  1 Y 1 A ARG 73  ? A ARG 73  
74  1 Y 1 A ARG 74  ? A ARG 74  
75  1 Y 1 A GLN 75  ? A GLN 75  
76  1 Y 1 A LEU 76  ? A LEU 76  
77  1 Y 1 A TYR 77  ? A TYR 77  
78  1 Y 1 A GLN 200 ? A GLN 200 
79  1 Y 1 A ALA 201 ? A ALA 201 
80  1 Y 1 A GLY 202 ? A GLY 202 
81  1 Y 1 A PRO 203 ? A PRO 203 
82  1 Y 1 A PRO 204 ? A PRO 204 
83  1 Y 1 A HIS 205 ? A HIS 205 
84  1 Y 1 A SER 206 ? A SER 206 
85  1 Y 1 A HIS 207 ? A HIS 207 
86  1 Y 1 A GLY 208 ? A GLY 208 
87  1 Y 1 A SER 209 ? A SER 209 
88  1 Y 1 A ARG 210 ? A ARG 210 
89  1 Y 1 A GLY 211 ? A GLY 211 
90  1 Y 1 A ALA 212 ? A ALA 212 
91  1 Y 1 A GLU 213 ? A GLU 213 
92  1 Y 1 A TYR 214 ? A TYR 214 
93  1 Y 1 A ALA 215 ? A ALA 215 
94  1 Y 1 A PRO 216 ? A PRO 216 
95  1 Y 1 A LEU 217 ? A LEU 217 
96  1 Y 1 A GLU 218 ? A GLU 218 
97  1 Y 1 A GLU 219 ? A GLU 219 
98  1 Y 1 A GLY 220 ? A GLY 220 
99  1 Y 1 A PRO 221 ? A PRO 221 
100 1 Y 1 A GLU 222 ? A GLU 222 
101 1 Y 1 A GLU 223 ? A GLU 223 
102 1 Y 1 A PRO 224 ? A PRO 224 
103 1 Y 1 A LEU 225 ? A LEU 225 
104 1 Y 1 A PRO 226 ? A PRO 226 
105 1 Y 1 A LEU 227 ? A LEU 227 
106 1 Y 1 A GLY 228 ? A GLY 228 
107 1 Y 1 A ASN 229 ? A ASN 229 
108 1 Y 1 A THR 230 ? A THR 230 
109 1 Y 1 A SER 231 ? A SER 231 
110 1 Y 1 A VAL 232 ? A VAL 232 
111 1 Y 1 A ARG 233 ? A ARG 233 
112 1 Y 1 A ALA 234 ? A ALA 234 
113 1 Y 1 A ALA 235 ? A ALA 235 
114 1 Y 1 A PHE 236 ? A PHE 236 
115 1 Y 1 A GLN 373 ? A GLN 373 
116 1 Y 1 A PRO 374 ? A PRO 374 
117 1 Y 1 A GLU 375 ? A GLU 375 
118 1 Y 1 A MET 376 ? A MET 376 
119 1 Y 1 A ALA 377 ? A ALA 377 
120 1 Y 1 A GLN 378 ? A GLN 378 
121 1 Y 1 A CYS 379 ? A CYS 379 
122 1 Y 1 A LEU 380 ? A LEU 380 
123 1 Y 1 A ARG 381 ? A ARG 381 
124 1 Y 1 A CYS 382 ? A CYS 382 
125 1 Y 1 A GLN 383 ? A GLN 383 
126 1 Y 1 A GLU 384 ? A GLU 384 
127 1 Y 1 A PRO 385 ? A PRO 385 
128 1 Y 1 A PRO 386 ? A PRO 386 
129 1 Y 1 A GLN 387 ? A GLN 387 
130 1 Y 1 A ALA 388 ? A ALA 388 
131 1 Y 1 A GLY 389 ? A GLY 389 
132 1 Y 1 A SER 390 ? A SER 390 
133 1 Y 1 A ILE 391 ? A ILE 391 
134 1 Y 1 A GLU 392 ? A GLU 392 
135 1 Y 1 A GLY 393 ? A GLY 393 
136 1 Y 1 A ARG 394 ? A ARG 394 
137 1 Y 1 A ILE 395 ? A ILE 395 
138 1 Y 1 A VAL 396 ? A VAL 396 
139 1 Y 1 A LYS 397 ? A LYS 397 
140 1 Y 1 A ASP 398 ? A ASP 398 
141 1 Y 1 A TYR 399 ? A TYR 399 
142 1 Y 1 A LYS 400 ? A LYS 400 
143 1 Y 1 A ASP 401 ? A ASP 401 
144 1 Y 1 A ASP 402 ? A ASP 402 
145 1 Y 1 A ASP 403 ? A ASP 403 
146 1 Y 1 A ASP 404 ? A ASP 404 
147 1 Y 1 A LYS 405 ? A LYS 405 
148 1 Y 1 B MET 1   ? B MET 1   
149 1 Y 1 B GLU 2   ? B GLU 2   
150 1 Y 1 B PRO 3   ? B PRO 3   
151 1 Y 1 B SER 4   ? B SER 4   
152 1 Y 1 B PRO 5   ? B PRO 5   
153 1 Y 1 B ALA 6   ? B ALA 6   
154 1 Y 1 B ALA 7   ? B ALA 7   
155 1 Y 1 B GLY 8   ? B GLY 8   
156 1 Y 1 B GLY 9   ? B GLY 9   
157 1 Y 1 B LEU 10  ? B LEU 10  
158 1 Y 1 B GLU 11  ? B GLU 11  
159 1 Y 1 B THR 12  ? B THR 12  
160 1 Y 1 B THR 13  ? B THR 13  
161 1 Y 1 B ARG 14  ? B ARG 14  
162 1 Y 1 B LEU 15  ? B LEU 15  
163 1 Y 1 B VAL 16  ? B VAL 16  
164 1 Y 1 B SER 17  ? B SER 17  
165 1 Y 1 B PRO 18  ? B PRO 18  
166 1 Y 1 B ARG 19  ? B ARG 19  
167 1 Y 1 B ASP 20  ? B ASP 20  
168 1 Y 1 B ARG 21  ? B ARG 21  
169 1 Y 1 B GLY 22  ? B GLY 22  
170 1 Y 1 B GLY 23  ? B GLY 23  
171 1 Y 1 B ALA 24  ? B ALA 24  
172 1 Y 1 B GLY 25  ? B GLY 25  
173 1 Y 1 B GLY 26  ? B GLY 26  
174 1 Y 1 B SER 27  ? B SER 27  
175 1 Y 1 B LEU 28  ? B LEU 28  
176 1 Y 1 B ARG 29  ? B ARG 29  
177 1 Y 1 B LEU 30  ? B LEU 30  
178 1 Y 1 B LYS 31  ? B LYS 31  
179 1 Y 1 B SER 32  ? B SER 32  
180 1 Y 1 B LEU 33  ? B LEU 33  
181 1 Y 1 B PHE 34  ? B PHE 34  
182 1 Y 1 B THR 35  ? B THR 35  
183 1 Y 1 B GLU 36  ? B GLU 36  
184 1 Y 1 B PRO 37  ? B PRO 37  
185 1 Y 1 B SER 38  ? B SER 38  
186 1 Y 1 B GLU 39  ? B GLU 39  
187 1 Y 1 B PRO 40  ? B PRO 40  
188 1 Y 1 B LEU 41  ? B LEU 41  
189 1 Y 1 B PRO 42  ? B PRO 42  
190 1 Y 1 B GLU 43  ? B GLU 43  
191 1 Y 1 B GLU 44  ? B GLU 44  
192 1 Y 1 B SER 45  ? B SER 45  
193 1 Y 1 B LYS 46  ? B LYS 46  
194 1 Y 1 B PRO 47  ? B PRO 47  
195 1 Y 1 B VAL 48  ? B VAL 48  
196 1 Y 1 B GLU 49  ? B GLU 49  
197 1 Y 1 B MET 50  ? B MET 50  
198 1 Y 1 B PRO 51  ? B PRO 51  
199 1 Y 1 B PHE 52  ? B PHE 52  
200 1 Y 1 B HIS 53  ? B HIS 53  
201 1 Y 1 B HIS 54  ? B HIS 54  
202 1 Y 1 B CYS 55  ? B CYS 55  
203 1 Y 1 B HIS 56  ? B HIS 56  
204 1 Y 1 B ARG 57  ? B ARG 57  
205 1 Y 1 B ASP 58  ? B ASP 58  
206 1 Y 1 B PRO 59  ? B PRO 59  
207 1 Y 1 B LEU 60  ? B LEU 60  
208 1 Y 1 B PRO 61  ? B PRO 61  
209 1 Y 1 B PRO 62  ? B PRO 62  
210 1 Y 1 B PRO 63  ? B PRO 63  
211 1 Y 1 B GLY 64  ? B GLY 64  
212 1 Y 1 B LEU 65  ? B LEU 65  
213 1 Y 1 B THR 66  ? B THR 66  
214 1 Y 1 B PRO 67  ? B PRO 67  
215 1 Y 1 B GLU 68  ? B GLU 68  
216 1 Y 1 B ARG 69  ? B ARG 69  
217 1 Y 1 B LEU 70  ? B LEU 70  
218 1 Y 1 B HIS 71  ? B HIS 71  
219 1 Y 1 B ALA 72  ? B ALA 72  
220 1 Y 1 B ARG 73  ? B ARG 73  
221 1 Y 1 B ARG 74  ? B ARG 74  
222 1 Y 1 B GLN 75  ? B GLN 75  
223 1 Y 1 B LEU 76  ? B LEU 76  
224 1 Y 1 B TYR 77  ? B TYR 77  
225 1 Y 1 B GLN 200 ? B GLN 200 
226 1 Y 1 B ALA 201 ? B ALA 201 
227 1 Y 1 B GLY 202 ? B GLY 202 
228 1 Y 1 B PRO 203 ? B PRO 203 
229 1 Y 1 B PRO 204 ? B PRO 204 
230 1 Y 1 B HIS 205 ? B HIS 205 
231 1 Y 1 B SER 206 ? B SER 206 
232 1 Y 1 B HIS 207 ? B HIS 207 
233 1 Y 1 B GLY 208 ? B GLY 208 
234 1 Y 1 B SER 209 ? B SER 209 
235 1 Y 1 B ARG 210 ? B ARG 210 
236 1 Y 1 B GLY 211 ? B GLY 211 
237 1 Y 1 B ALA 212 ? B ALA 212 
238 1 Y 1 B GLU 213 ? B GLU 213 
239 1 Y 1 B TYR 214 ? B TYR 214 
240 1 Y 1 B ALA 215 ? B ALA 215 
241 1 Y 1 B PRO 216 ? B PRO 216 
242 1 Y 1 B LEU 217 ? B LEU 217 
243 1 Y 1 B GLU 218 ? B GLU 218 
244 1 Y 1 B GLU 219 ? B GLU 219 
245 1 Y 1 B GLY 220 ? B GLY 220 
246 1 Y 1 B PRO 221 ? B PRO 221 
247 1 Y 1 B GLU 222 ? B GLU 222 
248 1 Y 1 B GLU 223 ? B GLU 223 
249 1 Y 1 B PRO 224 ? B PRO 224 
250 1 Y 1 B LEU 225 ? B LEU 225 
251 1 Y 1 B PRO 226 ? B PRO 226 
252 1 Y 1 B LEU 227 ? B LEU 227 
253 1 Y 1 B GLY 228 ? B GLY 228 
254 1 Y 1 B ASN 229 ? B ASN 229 
255 1 Y 1 B THR 230 ? B THR 230 
256 1 Y 1 B SER 231 ? B SER 231 
257 1 Y 1 B VAL 232 ? B VAL 232 
258 1 Y 1 B ARG 233 ? B ARG 233 
259 1 Y 1 B ALA 234 ? B ALA 234 
260 1 Y 1 B ALA 235 ? B ALA 235 
261 1 Y 1 B PHE 236 ? B PHE 236 
262 1 Y 1 B GLN 373 ? B GLN 373 
263 1 Y 1 B PRO 374 ? B PRO 374 
264 1 Y 1 B GLU 375 ? B GLU 375 
265 1 Y 1 B MET 376 ? B MET 376 
266 1 Y 1 B ALA 377 ? B ALA 377 
267 1 Y 1 B GLN 378 ? B GLN 378 
268 1 Y 1 B CYS 379 ? B CYS 379 
269 1 Y 1 B LEU 380 ? B LEU 380 
270 1 Y 1 B ARG 381 ? B ARG 381 
271 1 Y 1 B CYS 382 ? B CYS 382 
272 1 Y 1 B GLN 383 ? B GLN 383 
273 1 Y 1 B GLU 384 ? B GLU 384 
274 1 Y 1 B PRO 385 ? B PRO 385 
275 1 Y 1 B PRO 386 ? B PRO 386 
276 1 Y 1 B GLN 387 ? B GLN 387 
277 1 Y 1 B ALA 388 ? B ALA 388 
278 1 Y 1 B GLY 389 ? B GLY 389 
279 1 Y 1 B SER 390 ? B SER 390 
280 1 Y 1 B ILE 391 ? B ILE 391 
281 1 Y 1 B GLU 392 ? B GLU 392 
282 1 Y 1 B GLY 393 ? B GLY 393 
283 1 Y 1 B ARG 394 ? B ARG 394 
284 1 Y 1 B ILE 395 ? B ILE 395 
285 1 Y 1 B VAL 396 ? B VAL 396 
286 1 Y 1 B LYS 397 ? B LYS 397 
287 1 Y 1 B ASP 398 ? B ASP 398 
288 1 Y 1 B TYR 399 ? B TYR 399 
289 1 Y 1 B LYS 400 ? B LYS 400 
290 1 Y 1 B ASP 401 ? B ASP 401 
291 1 Y 1 B ASP 402 ? B ASP 402 
292 1 Y 1 B ASP 403 ? B ASP 403 
293 1 Y 1 B ASP 404 ? B ASP 404 
294 1 Y 1 B LYS 405 ? B LYS 405 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-09-12 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9JJ2 
_em_admin.last_update        2025-06-04 
_em_admin.map_release_date   2025-06-04 
_em_admin.title              'Cryo-EM structure of human ZnT3 under acidic conditions' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         65 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'        ? 3  1 ? 1 ?      ?            
MASKING                    ? 4  1 1 1 ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  1 1 1 ?      ?            
'DIFFRACTION INDEXING'     ? 7  1 1 1 ?      ?            
'MODEL FITTING'            ? 8  1 1 1 ?      ?            
OTHER                      ? 9  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Ministry of Education, Culture, Sports, Science and Technology (Japan)' 
_pdbx_audit_support.country                Japan 
_pdbx_audit_support.grant_number           
;20K16274 and 22K07131 (H.I.); 22K15046 and 24K09349 (Z.Z.); 19H00976, 22H05184, and 23H00366 (T.S.); and 19H03164 and 22H02556 [U.O.)
;
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9JJ2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 78  ? 115.681 98.741  109.614 1.00 166.53 ? 78  ALA A N   1 
ATOM 2    C CA  . ALA A 1 78  ? 114.998 99.013  110.873 1.00 171.29 ? 78  ALA A CA  1 
ATOM 3    C C   . ALA A 1 78  ? 115.960 98.910  112.052 1.00 173.73 ? 78  ALA A C   1 
ATOM 4    O O   . ALA A 1 78  ? 115.605 98.383  113.107 1.00 171.26 ? 78  ALA A O   1 
ATOM 5    C CB  . ALA A 1 78  ? 113.828 98.060  111.058 1.00 163.25 ? 78  ALA A CB  1 
ATOM 6    N N   . ALA A 1 79  ? 117.182 99.411  111.866 1.00 172.74 ? 79  ALA A N   1 
ATOM 7    C CA  . ALA A 1 79  ? 118.176 99.348  112.933 1.00 169.32 ? 79  ALA A CA  1 
ATOM 8    C C   . ALA A 1 79  ? 117.744 100.183 114.131 1.00 172.79 ? 79  ALA A C   1 
ATOM 9    O O   . ALA A 1 79  ? 117.688 99.687  115.261 1.00 174.96 ? 79  ALA A O   1 
ATOM 10   C CB  . ALA A 1 79  ? 119.538 99.807  112.410 1.00 161.69 ? 79  ALA A CB  1 
ATOM 11   N N   . CYS A 1 80  ? 117.402 101.452 113.898 1.00 175.02 ? 80  CYS A N   1 
ATOM 12   C CA  . CYS A 1 80  ? 116.941 102.307 114.986 1.00 177.81 ? 80  CYS A CA  1 
ATOM 13   C C   . CYS A 1 80  ? 115.529 101.984 115.446 1.00 177.74 ? 80  CYS A C   1 
ATOM 14   O O   . CYS A 1 80  ? 115.076 102.568 116.435 1.00 177.65 ? 80  CYS A O   1 
ATOM 15   C CB  . CYS A 1 80  ? 117.021 103.780 114.589 1.00 180.92 ? 80  CYS A CB  1 
ATOM 16   S SG  . CYS A 1 80  ? 118.679 104.465 114.692 1.00 178.84 ? 80  CYS A SG  1 
ATOM 17   N N   . ALA A 1 81  ? 114.819 101.088 114.758 1.00 177.05 ? 81  ALA A N   1 
ATOM 18   C CA  . ALA A 1 81  ? 113.521 100.658 115.263 1.00 179.72 ? 81  ALA A CA  1 
ATOM 19   C C   . ALA A 1 81  ? 113.652 99.992  116.626 1.00 181.46 ? 81  ALA A C   1 
ATOM 20   O O   . ALA A 1 81  ? 112.685 99.958  117.397 1.00 183.82 ? 81  ALA A O   1 
ATOM 21   C CB  . ALA A 1 81  ? 112.851 99.714  114.267 1.00 177.06 ? 81  ALA A CB  1 
ATOM 22   N N   . VAL A 1 82  ? 114.837 99.464  116.944 1.00 180.31 ? 82  VAL A N   1 
ATOM 23   C CA  . VAL A 1 82  ? 115.086 98.851  118.245 1.00 179.44 ? 82  VAL A CA  1 
ATOM 24   C C   . VAL A 1 82  ? 116.112 99.617  119.070 1.00 175.76 ? 82  VAL A C   1 
ATOM 25   O O   . VAL A 1 82  ? 116.216 99.374  120.284 1.00 173.11 ? 82  VAL A O   1 
ATOM 26   C CB  . VAL A 1 82  ? 115.533 97.381  118.088 1.00 181.38 ? 82  VAL A CB  1 
ATOM 27   C CG1 . VAL A 1 82  ? 117.026 97.302  117.807 1.00 179.48 ? 82  VAL A CG1 1 
ATOM 28   C CG2 . VAL A 1 82  ? 115.162 96.569  119.321 1.00 180.21 ? 82  VAL A CG2 1 
ATOM 29   N N   . CYS A 1 83  ? 116.869 100.531 118.465 1.00 175.78 ? 83  CYS A N   1 
ATOM 30   C CA  . CYS A 1 83  ? 117.852 101.319 119.195 1.00 171.63 ? 83  CYS A CA  1 
ATOM 31   C C   . CYS A 1 83  ? 117.376 102.725 119.521 1.00 168.44 ? 83  CYS A C   1 
ATOM 32   O O   . CYS A 1 83  ? 118.105 103.469 120.184 1.00 163.40 ? 83  CYS A O   1 
ATOM 33   C CB  . CYS A 1 83  ? 119.172 101.387 118.420 1.00 168.25 ? 83  CYS A CB  1 
ATOM 34   S SG  . CYS A 1 83  ? 119.608 99.857  117.582 1.00 171.58 ? 83  CYS A SG  1 
ATOM 35   N N   . PHE A 1 84  ? 116.183 103.116 119.074 1.00 171.55 ? 84  PHE A N   1 
ATOM 36   C CA  . PHE A 1 84  ? 115.599 104.352 119.578 1.00 171.73 ? 84  PHE A CA  1 
ATOM 37   C C   . PHE A 1 84  ? 115.077 104.162 120.994 1.00 172.47 ? 84  PHE A C   1 
ATOM 38   O O   . PHE A 1 84  ? 115.252 105.036 121.851 1.00 173.45 ? 84  PHE A O   1 
ATOM 39   C CB  . PHE A 1 84  ? 114.486 104.832 118.649 1.00 177.93 ? 84  PHE A CB  1 
ATOM 40   C CG  . PHE A 1 84  ? 114.480 106.316 118.433 1.00 180.82 ? 84  PHE A CG  1 
ATOM 41   C CD1 . PHE A 1 84  ? 114.474 107.185 119.511 1.00 181.17 ? 84  PHE A CD1 1 
ATOM 42   C CD2 . PHE A 1 84  ? 114.490 106.843 117.153 1.00 181.64 ? 84  PHE A CD2 1 
ATOM 43   C CE1 . PHE A 1 84  ? 114.471 108.552 119.317 1.00 184.95 ? 84  PHE A CE1 1 
ATOM 44   C CE2 . PHE A 1 84  ? 114.487 108.210 116.952 1.00 183.46 ? 84  PHE A CE2 1 
ATOM 45   C CZ  . PHE A 1 84  ? 114.478 109.065 118.036 1.00 185.15 ? 84  PHE A CZ  1 
ATOM 46   N N   . VAL A 1 85  ? 114.433 103.024 121.259 1.00 173.70 ? 85  VAL A N   1 
ATOM 47   C CA  . VAL A 1 85  ? 114.048 102.691 122.625 1.00 173.55 ? 85  VAL A CA  1 
ATOM 48   C C   . VAL A 1 85  ? 115.286 102.405 123.465 1.00 170.59 ? 85  VAL A C   1 
ATOM 49   O O   . VAL A 1 85  ? 115.339 102.739 124.654 1.00 169.04 ? 85  VAL A O   1 
ATOM 50   C CB  . VAL A 1 85  ? 113.060 101.509 122.632 1.00 174.39 ? 85  VAL A CB  1 
ATOM 51   C CG1 . VAL A 1 85  ? 113.610 100.342 121.831 1.00 174.45 ? 85  VAL A CG1 1 
ATOM 52   C CG2 . VAL A 1 85  ? 112.738 101.082 124.057 1.00 175.20 ? 85  VAL A CG2 1 
ATOM 53   N N   . PHE A 1 86  ? 116.302 101.785 122.861 1.00 169.17 ? 86  PHE A N   1 
ATOM 54   C CA  . PHE A 1 86  ? 117.556 101.565 123.572 1.00 166.43 ? 86  PHE A CA  1 
ATOM 55   C C   . PHE A 1 86  ? 118.217 102.890 123.924 1.00 160.75 ? 86  PHE A C   1 
ATOM 56   O O   . PHE A 1 86  ? 118.798 103.035 125.005 1.00 157.05 ? 86  PHE A O   1 
ATOM 57   C CB  . PHE A 1 86  ? 118.491 100.698 122.732 1.00 164.44 ? 86  PHE A CB  1 
ATOM 58   C CG  . PHE A 1 86  ? 118.536 99.264  123.169 1.00 167.29 ? 86  PHE A CG  1 
ATOM 59   C CD1 . PHE A 1 86  ? 117.501 98.724  123.915 1.00 170.80 ? 86  PHE A CD1 1 
ATOM 60   C CD2 . PHE A 1 86  ? 119.604 98.455  122.831 1.00 162.85 ? 86  PHE A CD2 1 
ATOM 61   C CE1 . PHE A 1 86  ? 117.533 97.404  124.317 1.00 171.15 ? 86  PHE A CE1 1 
ATOM 62   C CE2 . PHE A 1 86  ? 119.643 97.134  123.231 1.00 165.65 ? 86  PHE A CE2 1 
ATOM 63   C CZ  . PHE A 1 86  ? 118.606 96.608  123.975 1.00 171.34 ? 86  PHE A CZ  1 
ATOM 64   N N   . MET A 1 87  ? 118.134 103.870 123.021 1.00 159.82 ? 87  MET A N   1 
ATOM 65   C CA  . MET A 1 87  ? 118.611 105.214 123.328 1.00 153.34 ? 87  MET A CA  1 
ATOM 66   C C   . MET A 1 87  ? 117.932 105.782 124.564 1.00 154.55 ? 87  MET A C   1 
ATOM 67   O O   . MET A 1 87  ? 118.557 106.514 125.340 1.00 152.00 ? 87  MET A O   1 
ATOM 68   C CB  . MET A 1 87  ? 118.380 106.142 122.142 1.00 150.09 ? 87  MET A CB  1 
ATOM 69   C CG  . MET A 1 87  ? 119.296 107.337 122.142 1.00 142.70 ? 87  MET A CG  1 
ATOM 70   S SD  . MET A 1 87  ? 119.494 108.092 120.528 1.00 151.41 ? 87  MET A SD  1 
ATOM 71   C CE  . MET A 1 87  ? 120.317 109.594 121.024 1.00 135.59 ? 87  MET A CE  1 
ATOM 72   N N   . ALA A 1 88  ? 116.647 105.478 124.753 1.00 158.46 ? 88  ALA A N   1 
ATOM 73   C CA  . ALA A 1 88  ? 115.951 105.962 125.938 1.00 157.06 ? 88  ALA A CA  1 
ATOM 74   C C   . ALA A 1 88  ? 116.625 105.459 127.205 1.00 154.69 ? 88  ALA A C   1 
ATOM 75   O O   . ALA A 1 88  ? 116.767 106.206 128.179 1.00 154.23 ? 88  ALA A O   1 
ATOM 76   C CB  . ALA A 1 88  ? 114.484 105.538 125.901 1.00 163.38 ? 88  ALA A CB  1 
ATOM 77   N N   . GLY A 1 89  ? 117.073 104.201 127.199 1.00 155.31 ? 89  GLY A N   1 
ATOM 78   C CA  . GLY A 1 89  ? 117.762 103.660 128.357 1.00 154.16 ? 89  GLY A CA  1 
ATOM 79   C C   . GLY A 1 89  ? 119.051 104.386 128.680 1.00 149.33 ? 89  GLY A C   1 
ATOM 80   O O   . GLY A 1 89  ? 119.446 104.468 129.846 1.00 145.80 ? 89  GLY A O   1 
ATOM 81   N N   . GLU A 1 90  ? 119.732 104.909 127.659 1.00 150.03 ? 90  GLU A N   1 
ATOM 82   C CA  . GLU A 1 90  ? 120.942 105.688 127.902 1.00 146.68 ? 90  GLU A CA  1 
ATOM 83   C C   . GLU A 1 90  ? 120.638 106.957 128.684 1.00 150.02 ? 90  GLU A C   1 
ATOM 84   O O   . GLU A 1 90  ? 121.365 107.305 129.620 1.00 152.13 ? 90  GLU A O   1 
ATOM 85   C CB  . GLU A 1 90  ? 121.623 106.035 126.579 1.00 140.64 ? 90  GLU A CB  1 
ATOM 86   C CG  . GLU A 1 90  ? 122.823 105.170 126.204 1.00 137.08 ? 90  GLU A CG  1 
ATOM 87   C CD  . GLU A 1 90  ? 122.481 103.727 125.880 1.00 146.54 ? 90  GLU A CD  1 
ATOM 88   O OE1 . GLU A 1 90  ? 123.404 102.987 125.487 1.00 141.42 ? 90  GLU A OE1 1 
ATOM 89   O OE2 . GLU A 1 90  ? 121.309 103.325 125.995 1.00 154.92 ? 90  GLU A OE2 1 
ATOM 90   N N   . VAL A 1 91  ? 119.570 107.663 128.313 1.00 151.27 ? 91  VAL A N   1 
ATOM 91   C CA  . VAL A 1 91  ? 119.267 108.936 128.959 1.00 155.48 ? 91  VAL A CA  1 
ATOM 92   C C   . VAL A 1 91  ? 118.852 108.717 130.409 1.00 155.85 ? 91  VAL A C   1 
ATOM 93   O O   . VAL A 1 91  ? 119.355 109.385 131.320 1.00 155.30 ? 91  VAL A O   1 
ATOM 94   C CB  . VAL A 1 91  ? 118.188 109.696 128.170 1.00 160.36 ? 91  VAL A CB  1 
ATOM 95   C CG1 . VAL A 1 91  ? 118.251 111.179 128.494 1.00 163.50 ? 91  VAL A CG1 1 
ATOM 96   C CG2 . VAL A 1 91  ? 118.370 109.467 126.681 1.00 155.62 ? 91  VAL A CG2 1 
ATOM 97   N N   . VAL A 1 92  ? 117.931 107.782 130.649 1.00 154.57 ? 92  VAL A N   1 
ATOM 98   C CA  . VAL A 1 92  ? 117.488 107.546 132.020 1.00 155.05 ? 92  VAL A CA  1 
ATOM 99   C C   . VAL A 1 92  ? 118.593 106.877 132.827 1.00 153.65 ? 92  VAL A C   1 
ATOM 100  O O   . VAL A 1 92  ? 118.871 107.270 133.965 1.00 152.88 ? 92  VAL A O   1 
ATOM 101  C CB  . VAL A 1 92  ? 116.187 106.721 132.045 1.00 158.07 ? 92  VAL A CB  1 
ATOM 102  C CG1 . VAL A 1 92  ? 116.277 105.524 131.119 1.00 155.75 ? 92  VAL A CG1 1 
ATOM 103  C CG2 . VAL A 1 92  ? 115.867 106.278 133.464 1.00 157.72 ? 92  VAL A CG2 1 
ATOM 104  N N   . GLY A 1 93  ? 119.249 105.869 132.248 1.00 150.72 ? 93  GLY A N   1 
ATOM 105  C CA  . GLY A 1 93  ? 120.298 105.168 132.970 1.00 148.79 ? 93  GLY A CA  1 
ATOM 106  C C   . GLY A 1 93  ? 121.444 106.079 133.360 1.00 148.00 ? 93  GLY A C   1 
ATOM 107  O O   . GLY A 1 93  ? 121.979 105.983 134.467 1.00 146.25 ? 93  GLY A O   1 
ATOM 108  N N   . GLY A 1 94  ? 121.836 106.977 132.456 1.00 145.59 ? 94  GLY A N   1 
ATOM 109  C CA  . GLY A 1 94  ? 122.843 107.960 132.803 1.00 142.62 ? 94  GLY A CA  1 
ATOM 110  C C   . GLY A 1 94  ? 122.345 108.990 133.794 1.00 148.64 ? 94  GLY A C   1 
ATOM 111  O O   . GLY A 1 94  ? 123.138 109.577 134.535 1.00 147.82 ? 94  GLY A O   1 
ATOM 112  N N   . TYR A 1 95  ? 121.033 109.228 133.825 1.00 150.42 ? 95  TYR A N   1 
ATOM 113  C CA  . TYR A 1 95  ? 120.476 110.145 134.813 1.00 149.70 ? 95  TYR A CA  1 
ATOM 114  C C   . TYR A 1 95  ? 120.593 109.562 136.216 1.00 147.75 ? 95  TYR A C   1 
ATOM 115  O O   . TYR A 1 95  ? 121.058 110.237 137.142 1.00 147.24 ? 95  TYR A O   1 
ATOM 116  C CB  . TYR A 1 95  ? 119.018 110.459 134.476 1.00 150.62 ? 95  TYR A CB  1 
ATOM 117  C CG  . TYR A 1 95  ? 118.411 111.591 135.281 1.00 155.72 ? 95  TYR A CG  1 
ATOM 118  C CD1 . TYR A 1 95  ? 117.047 111.843 135.236 1.00 157.60 ? 95  TYR A CD1 1 
ATOM 119  C CD2 . TYR A 1 95  ? 119.204 112.426 136.061 1.00 157.31 ? 95  TYR A CD2 1 
ATOM 120  C CE1 . TYR A 1 95  ? 116.486 112.875 135.963 1.00 159.69 ? 95  TYR A CE1 1 
ATOM 121  C CE2 . TYR A 1 95  ? 118.653 113.459 136.789 1.00 158.71 ? 95  TYR A CE2 1 
ATOM 122  C CZ  . TYR A 1 95  ? 117.294 113.681 136.736 1.00 161.39 ? 95  TYR A CZ  1 
ATOM 123  O OH  . TYR A 1 95  ? 116.739 114.712 137.458 1.00 161.48 ? 95  TYR A OH  1 
ATOM 124  N N   . LEU A 1 96  ? 120.179 108.305 136.392 1.00 147.15 ? 96  LEU A N   1 
ATOM 125  C CA  . LEU A 1 96  ? 120.301 107.668 137.699 1.00 148.09 ? 96  LEU A CA  1 
ATOM 126  C C   . LEU A 1 96  ? 121.762 107.515 138.099 1.00 148.60 ? 96  LEU A C   1 
ATOM 127  O O   . LEU A 1 96  ? 122.124 107.742 139.259 1.00 152.01 ? 96  LEU A O   1 
ATOM 128  C CB  . LEU A 1 96  ? 119.603 106.307 137.700 1.00 145.75 ? 96  LEU A CB  1 
ATOM 129  C CG  . LEU A 1 96  ? 118.395 106.095 136.787 1.00 144.29 ? 96  LEU A CG  1 
ATOM 130  C CD1 . LEU A 1 96  ? 117.872 104.676 136.919 1.00 141.03 ? 96  LEU A CD1 1 
ATOM 131  C CD2 . LEU A 1 96  ? 117.294 107.096 137.101 1.00 146.36 ? 96  LEU A CD2 1 
ATOM 132  N N   . ALA A 1 97  ? 122.617 107.136 137.149 1.00 145.79 ? 97  ALA A N   1 
ATOM 133  C CA  . ALA A 1 97  ? 124.033 106.964 137.439 1.00 141.86 ? 97  ALA A CA  1 
ATOM 134  C C   . ALA A 1 97  ? 124.766 108.285 137.611 1.00 140.48 ? 97  ALA A C   1 
ATOM 135  O O   . ALA A 1 97  ? 125.898 108.278 138.107 1.00 140.46 ? 97  ALA A O   1 
ATOM 136  C CB  . ALA A 1 97  ? 124.700 106.149 136.332 1.00 137.32 ? 97  ALA A CB  1 
ATOM 137  N N   . HIS A 1 98  ? 124.150 109.405 137.229 1.00 139.61 ? 98  HIS A N   1 
ATOM 138  C CA  . HIS A 1 98  ? 124.799 110.715 137.263 1.00 139.75 ? 98  HIS A CA  1 
ATOM 139  C C   . HIS A 1 98  ? 126.125 110.683 136.511 1.00 139.17 ? 98  HIS A C   1 
ATOM 140  O O   . HIS A 1 98  ? 127.131 111.237 136.955 1.00 140.74 ? 98  HIS A O   1 
ATOM 141  C CB  . HIS A 1 98  ? 125.004 111.199 138.701 1.00 142.58 ? 98  HIS A CB  1 
ATOM 142  C CG  . HIS A 1 98  ? 123.925 110.774 139.646 1.00 144.67 ? 98  HIS A CG  1 
ATOM 143  N ND1 . HIS A 1 98  ? 124.175 110.011 140.766 1.00 142.44 ? 98  HIS A ND1 1 
ATOM 144  C CD2 . HIS A 1 98  ? 122.592 111.016 139.646 1.00 146.64 ? 98  HIS A CD2 1 
ATOM 145  C CE1 . HIS A 1 98  ? 123.043 109.794 141.411 1.00 144.19 ? 98  HIS A CE1 1 
ATOM 146  N NE2 . HIS A 1 98  ? 122.067 110.393 140.752 1.00 147.33 ? 98  HIS A NE2 1 
ATOM 147  N N   . SER A 1 99  ? 126.127 110.022 135.359 1.00 135.62 ? 99  SER A N   1 
ATOM 148  C CA  . SER A 1 99  ? 127.342 109.778 134.601 1.00 126.13 ? 99  SER A CA  1 
ATOM 149  C C   . SER A 1 99  ? 127.355 110.604 133.323 1.00 121.08 ? 99  SER A C   1 
ATOM 150  O O   . SER A 1 99  ? 126.317 111.050 132.829 1.00 125.41 ? 99  SER A O   1 
ATOM 151  C CB  . SER A 1 99  ? 127.482 108.292 134.263 1.00 123.43 ? 99  SER A CB  1 
ATOM 152  O OG  . SER A 1 99  ? 128.503 108.077 133.308 1.00 121.16 ? 99  SER A OG  1 
ATOM 153  N N   . LEU A 1 100 ? 128.560 110.807 132.794 1.00 115.58 ? 100 LEU A N   1 
ATOM 154  C CA  . LEU A 1 100 ? 128.758 111.553 131.565 1.00 116.24 ? 100 LEU A CA  1 
ATOM 155  C C   . LEU A 1 100 ? 129.324 110.717 130.428 1.00 122.82 ? 100 LEU A C   1 
ATOM 156  O O   . LEU A 1 100 ? 129.206 111.130 129.270 1.00 127.60 ? 100 LEU A O   1 
ATOM 157  C CB  . LEU A 1 100 ? 129.689 112.750 131.813 1.00 117.85 ? 100 LEU A CB  1 
ATOM 158  C CG  . LEU A 1 100 ? 129.053 114.136 131.736 1.00 120.82 ? 100 LEU A CG  1 
ATOM 159  C CD1 . LEU A 1 100 ? 127.977 114.281 132.791 1.00 115.39 ? 100 LEU A CD1 1 
ATOM 160  C CD2 . LEU A 1 100 ? 130.109 115.212 131.905 1.00 126.28 ? 100 LEU A CD2 1 
ATOM 161  N N   . ALA A 1 101 ? 129.936 109.567 130.717 1.00 119.22 ? 101 ALA A N   1 
ATOM 162  C CA  . ALA A 1 101 ? 130.350 108.665 129.648 1.00 113.35 ? 101 ALA A CA  1 
ATOM 163  C C   . ALA A 1 101 ? 129.142 108.086 128.926 1.00 115.80 ? 101 ALA A C   1 
ATOM 164  O O   . ALA A 1 101 ? 129.161 107.910 127.701 1.00 123.95 ? 101 ALA A O   1 
ATOM 165  C CB  . ALA A 1 101 ? 131.226 107.550 130.214 1.00 113.56 ? 101 ALA A CB  1 
ATOM 166  N N   . ILE A 1 102 ? 128.079 107.777 129.669 1.00 111.94 ? 102 ILE A N   1 
ATOM 167  C CA  . ILE A 1 102 ? 126.841 107.359 129.028 1.00 108.42 ? 102 ILE A CA  1 
ATOM 168  C C   . ILE A 1 102 ? 126.311 108.464 128.133 1.00 111.36 ? 102 ILE A C   1 
ATOM 169  O O   . ILE A 1 102 ? 125.698 108.193 127.096 1.00 118.00 ? 102 ILE A O   1 
ATOM 170  C CB  . ILE A 1 102 ? 125.803 106.943 130.083 1.00 114.07 ? 102 ILE A CB  1 
ATOM 171  C CG1 . ILE A 1 102 ? 126.496 106.309 131.289 1.00 115.59 ? 102 ILE A CG1 1 
ATOM 172  C CG2 . ILE A 1 102 ? 124.803 105.996 129.475 1.00 123.99 ? 102 ILE A CG2 1 
ATOM 173  C CD1 . ILE A 1 102 ? 127.015 104.916 131.028 1.00 115.18 ? 102 ILE A CD1 1 
ATOM 174  N N   . MET A 1 103 ? 126.541 109.722 128.507 1.00 110.65 ? 103 MET A N   1 
ATOM 175  C CA  . MET A 1 103 ? 126.148 110.827 127.641 1.00 113.47 ? 103 MET A CA  1 
ATOM 176  C C   . MET A 1 103 ? 126.923 110.823 126.330 1.00 118.43 ? 103 MET A C   1 
ATOM 177  O O   . MET A 1 103 ? 126.357 111.126 125.278 1.00 123.23 ? 103 MET A O   1 
ATOM 178  C CB  . MET A 1 103 ? 126.313 112.158 128.369 1.00 115.19 ? 103 MET A CB  1 
ATOM 179  C CG  . MET A 1 103 ? 125.369 112.361 129.539 1.00 120.83 ? 103 MET A CG  1 
ATOM 180  S SD  . MET A 1 103 ? 123.874 111.365 129.400 1.00 126.85 ? 103 MET A SD  1 
ATOM 181  C CE  . MET A 1 103 ? 123.597 110.936 131.110 1.00 126.78 ? 103 MET A CE  1 
ATOM 182  N N   . THR A 1 104 ? 128.215 110.488 126.356 1.00 117.43 ? 104 THR A N   1 
ATOM 183  C CA  . THR A 1 104 ? 128.951 110.417 125.095 1.00 117.96 ? 104 THR A CA  1 
ATOM 184  C C   . THR A 1 104 ? 128.529 109.209 124.263 1.00 121.10 ? 104 THR A C   1 
ATOM 185  O O   . THR A 1 104 ? 128.496 109.288 123.027 1.00 126.85 ? 104 THR A O   1 
ATOM 186  C CB  . THR A 1 104 ? 130.458 110.400 125.347 1.00 119.87 ? 104 THR A CB  1 
ATOM 187  O OG1 . THR A 1 104 ? 130.756 109.575 126.476 1.00 122.99 ? 104 THR A OG1 1 
ATOM 188  C CG2 . THR A 1 104 ? 130.958 111.805 125.616 1.00 123.79 ? 104 THR A CG2 1 
ATOM 189  N N   . ASP A 1 105 ? 128.194 108.092 124.914 1.00 120.22 ? 105 ASP A N   1 
ATOM 190  C CA  . ASP A 1 105 ? 127.598 106.974 124.188 1.00 116.66 ? 105 ASP A CA  1 
ATOM 191  C C   . ASP A 1 105 ? 126.310 107.406 123.498 1.00 117.71 ? 105 ASP A C   1 
ATOM 192  O O   . ASP A 1 105 ? 126.088 107.115 122.315 1.00 123.45 ? 105 ASP A O   1 
ATOM 193  C CB  . ASP A 1 105 ? 127.323 105.817 125.146 1.00 115.19 ? 105 ASP A CB  1 
ATOM 194  C CG  . ASP A 1 105 ? 128.446 104.812 125.181 1.00 121.62 ? 105 ASP A CG  1 
ATOM 195  O OD1 . ASP A 1 105 ? 128.311 103.793 125.889 1.00 121.58 ? 105 ASP A OD1 1 
ATOM 196  O OD2 . ASP A 1 105 ? 129.463 105.036 124.498 1.00 129.48 ? 105 ASP A OD2 1 
ATOM 197  N N   . ALA A 1 106 ? 125.452 108.116 124.229 1.00 115.79 ? 106 ALA A N   1 
ATOM 198  C CA  . ALA A 1 106 ? 124.212 108.615 123.655 1.00 117.95 ? 106 ALA A CA  1 
ATOM 199  C C   . ALA A 1 106 ? 124.475 109.635 122.558 1.00 124.23 ? 106 ALA A C   1 
ATOM 200  O O   . ALA A 1 106 ? 123.691 109.734 121.616 1.00 133.42 ? 106 ALA A O   1 
ATOM 201  C CB  . ALA A 1 106 ? 123.333 109.221 124.746 1.00 116.14 ? 106 ALA A CB  1 
ATOM 202  N N   . ALA A 1 107 ? 125.565 110.396 122.657 1.00 120.23 ? 107 ALA A N   1 
ATOM 203  C CA  . ALA A 1 107 ? 125.898 111.350 121.604 1.00 120.73 ? 107 ALA A CA  1 
ATOM 204  C C   . ALA A 1 107 ? 126.308 110.639 120.321 1.00 124.53 ? 107 ALA A C   1 
ATOM 205  O O   . ALA A 1 107 ? 125.905 111.043 119.224 1.00 128.97 ? 107 ALA A O   1 
ATOM 206  C CB  . ALA A 1 107 ? 127.006 112.288 122.076 1.00 117.43 ? 107 ALA A CB  1 
ATOM 207  N N   . HIS A 1 108 ? 127.114 109.583 120.435 1.00 122.42 ? 108 HIS A N   1 
ATOM 208  C CA  . HIS A 1 108 ? 127.448 108.790 119.255 1.00 122.86 ? 108 HIS A CA  1 
ATOM 209  C C   . HIS A 1 108 ? 126.194 108.169 118.646 1.00 127.56 ? 108 HIS A C   1 
ATOM 210  O O   . HIS A 1 108 ? 125.999 108.190 117.418 1.00 130.55 ? 108 HIS A O   1 
ATOM 211  C CB  . HIS A 1 108 ? 128.452 107.699 119.623 1.00 126.77 ? 108 HIS A CB  1 
ATOM 212  C CG  . HIS A 1 108 ? 129.878 108.077 119.378 1.00 130.18 ? 108 HIS A CG  1 
ATOM 213  N ND1 . HIS A 1 108 ? 130.497 107.896 118.161 1.00 136.27 ? 108 HIS A ND1 1 
ATOM 214  C CD2 . HIS A 1 108 ? 130.815 108.604 120.201 1.00 129.69 ? 108 HIS A CD2 1 
ATOM 215  C CE1 . HIS A 1 108 ? 131.750 108.306 118.240 1.00 134.05 ? 108 HIS A CE1 1 
ATOM 216  N NE2 . HIS A 1 108 ? 131.969 108.739 119.468 1.00 129.66 ? 108 HIS A NE2 1 
ATOM 217  N N   . LEU A 1 109 ? 125.329 107.616 119.499 1.00 127.64 ? 109 LEU A N   1 
ATOM 218  C CA  . LEU A 1 109 ? 124.080 107.046 119.012 1.00 129.73 ? 109 LEU A CA  1 
ATOM 219  C C   . LEU A 1 109 ? 123.216 108.109 118.352 1.00 134.33 ? 109 LEU A C   1 
ATOM 220  O O   . LEU A 1 109 ? 122.546 107.838 117.354 1.00 141.22 ? 109 LEU A O   1 
ATOM 221  C CB  . LEU A 1 109 ? 123.326 106.373 120.158 1.00 129.27 ? 109 LEU A CB  1 
ATOM 222  C CG  . LEU A 1 109 ? 122.626 105.059 119.813 1.00 129.65 ? 109 LEU A CG  1 
ATOM 223  C CD1 . LEU A 1 109 ? 123.641 103.941 119.658 1.00 125.14 ? 109 LEU A CD1 1 
ATOM 224  C CD2 . LEU A 1 109 ? 121.596 104.707 120.872 1.00 137.78 ? 109 LEU A CD2 1 
ATOM 225  N N   . LEU A 1 110 ? 123.218 109.326 118.896 1.00 131.62 ? 110 LEU A N   1 
ATOM 226  C CA  . LEU A 1 110 ? 122.464 110.419 118.298 1.00 131.55 ? 110 LEU A CA  1 
ATOM 227  C C   . LEU A 1 110 ? 123.018 110.777 116.932 1.00 136.19 ? 110 LEU A C   1 
ATOM 228  O O   . LEU A 1 110 ? 122.255 111.084 116.013 1.00 144.16 ? 110 LEU A O   1 
ATOM 229  C CB  . LEU A 1 110 ? 122.471 111.633 119.235 1.00 130.25 ? 110 LEU A CB  1 
ATOM 230  C CG  . LEU A 1 110 ? 121.973 113.030 118.842 1.00 134.17 ? 110 LEU A CG  1 
ATOM 231  C CD1 . LEU A 1 110 ? 121.766 113.839 120.105 1.00 138.05 ? 110 LEU A CD1 1 
ATOM 232  C CD2 . LEU A 1 110 ? 122.944 113.776 117.946 1.00 126.91 ? 110 LEU A CD2 1 
ATOM 233  N N   . ALA A 1 111 ? 124.341 110.778 116.788 1.00 134.04 ? 111 ALA A N   1 
ATOM 234  C CA  . ALA A 1 111 ? 124.931 111.052 115.483 1.00 136.51 ? 111 ALA A CA  1 
ATOM 235  C C   . ALA A 1 111 ? 124.465 110.031 114.456 1.00 142.04 ? 111 ALA A C   1 
ATOM 236  O O   . ALA A 1 111 ? 124.033 110.392 113.356 1.00 143.86 ? 111 ALA A O   1 
ATOM 237  C CB  . ALA A 1 111 ? 126.454 111.060 115.585 1.00 133.82 ? 111 ALA A CB  1 
ATOM 238  N N   . ASP A 1 112 ? 124.517 108.745 114.818 1.00 142.14 ? 112 ASP A N   1 
ATOM 239  C CA  . ASP A 1 112 ? 124.086 107.698 113.890 1.00 146.06 ? 112 ASP A CA  1 
ATOM 240  C C   . ASP A 1 112 ? 122.589 107.823 113.593 1.00 148.01 ? 112 ASP A C   1 
ATOM 241  O O   . ASP A 1 112 ? 122.161 107.717 112.429 1.00 151.30 ? 112 ASP A O   1 
ATOM 242  C CB  . ASP A 1 112 ? 124.463 106.330 114.490 1.00 149.55 ? 112 ASP A CB  1 
ATOM 243  C CG  . ASP A 1 112 ? 123.650 105.142 113.949 1.00 157.70 ? 112 ASP A CG  1 
ATOM 244  O OD1 . ASP A 1 112 ? 123.889 104.028 114.454 1.00 158.96 ? 112 ASP A OD1 1 
ATOM 245  O OD2 . ASP A 1 112 ? 122.854 105.252 112.997 1.00 159.02 ? 112 ASP A OD2 1 
ATOM 246  N N   . VAL A 1 113 ? 121.785 108.057 114.635 1.00 146.85 ? 113 VAL A N   1 
ATOM 247  C CA  . VAL A 1 113 ? 120.340 108.181 114.474 1.00 146.18 ? 113 VAL A CA  1 
ATOM 248  C C   . VAL A 1 113 ? 120.019 109.321 113.525 1.00 148.89 ? 113 VAL A C   1 
ATOM 249  O O   . VAL A 1 113 ? 119.258 109.157 112.568 1.00 155.94 ? 113 VAL A O   1 
ATOM 250  C CB  . VAL A 1 113 ? 119.660 108.394 115.840 1.00 145.73 ? 113 VAL A CB  1 
ATOM 251  C CG1 . VAL A 1 113 ? 118.269 108.998 115.657 1.00 151.35 ? 113 VAL A CG1 1 
ATOM 252  C CG2 . VAL A 1 113 ? 119.582 107.099 116.624 1.00 147.21 ? 113 VAL A CG2 1 
ATOM 253  N N   . GLY A 1 114 ? 120.602 110.493 113.774 1.00 145.59 ? 114 GLY A N   1 
ATOM 254  C CA  . GLY A 1 114 ? 120.352 111.629 112.911 1.00 146.58 ? 114 GLY A CA  1 
ATOM 255  C C   . GLY A 1 114 ? 120.809 111.382 111.490 1.00 148.35 ? 114 GLY A C   1 
ATOM 256  O O   . GLY A 1 114 ? 120.103 111.719 110.539 1.00 150.20 ? 114 GLY A O   1 
ATOM 257  N N   . SER A 1 115 ? 121.976 110.754 111.324 1.00 147.27 ? 115 SER A N   1 
ATOM 258  C CA  . SER A 1 115 ? 122.496 110.529 109.981 1.00 149.94 ? 115 SER A CA  1 
ATOM 259  C C   . SER A 1 115 ? 121.544 109.669 109.160 1.00 154.75 ? 115 SER A C   1 
ATOM 260  O O   . SER A 1 115 ? 121.121 110.067 108.067 1.00 157.54 ? 115 SER A O   1 
ATOM 261  C CB  . SER A 1 115 ? 123.888 109.895 110.048 1.00 148.98 ? 115 SER A CB  1 
ATOM 262  O OG  . SER A 1 115 ? 123.830 108.524 110.393 1.00 153.84 ? 115 SER A OG  1 
ATOM 263  N N   . MET A 1 116 ? 121.144 108.507 109.678 1.00 154.18 ? 116 MET A N   1 
ATOM 264  C CA  . MET A 1 116 ? 120.341 107.688 108.778 1.00 152.10 ? 116 MET A CA  1 
ATOM 265  C C   . MET A 1 116 ? 118.847 107.996 108.849 1.00 151.46 ? 116 MET A C   1 
ATOM 266  O O   . MET A 1 116 ? 118.123 107.667 107.902 1.00 153.59 ? 116 MET A O   1 
ATOM 267  C CB  . MET A 1 116 ? 120.591 106.187 108.979 1.00 150.00 ? 116 MET A CB  1 
ATOM 268  C CG  . MET A 1 116 ? 119.701 105.433 109.935 1.00 149.34 ? 116 MET A CG  1 
ATOM 269  S SD  . MET A 1 116 ? 120.599 103.956 110.452 1.00 146.58 ? 116 MET A SD  1 
ATOM 270  C CE  . MET A 1 116 ? 119.524 103.313 111.714 1.00 150.81 ? 116 MET A CE  1 
ATOM 271  N N   . MET A 1 117 ? 118.372 108.682 109.891 1.00 150.98 ? 117 MET A N   1 
ATOM 272  C CA  . MET A 1 117 ? 117.031 109.252 109.830 1.00 153.56 ? 117 MET A CA  1 
ATOM 273  C C   . MET A 1 117 ? 116.952 110.333 108.762 1.00 154.74 ? 117 MET A C   1 
ATOM 274  O O   . MET A 1 117 ? 115.967 110.409 108.018 1.00 154.65 ? 117 MET A O   1 
ATOM 275  C CB  . MET A 1 117 ? 116.639 109.813 111.195 1.00 155.53 ? 117 MET A CB  1 
ATOM 276  C CG  . MET A 1 117 ? 115.262 110.445 111.232 1.00 159.67 ? 117 MET A CG  1 
ATOM 277  S SD  . MET A 1 117 ? 115.324 112.188 111.689 1.00 171.21 ? 117 MET A SD  1 
ATOM 278  C CE  . MET A 1 117 ? 115.354 112.070 113.475 1.00 164.40 ? 117 MET A CE  1 
ATOM 279  N N   . GLY A 1 118 ? 117.983 111.177 108.668 1.00 154.08 ? 118 GLY A N   1 
ATOM 280  C CA  . GLY A 1 118 ? 118.051 112.127 107.578 1.00 151.39 ? 118 GLY A CA  1 
ATOM 281  C C   . GLY A 1 118 ? 118.175 111.451 106.231 1.00 151.94 ? 118 GLY A C   1 
ATOM 282  O O   . GLY A 1 118 ? 117.640 111.943 105.241 1.00 151.03 ? 118 GLY A O   1 
ATOM 283  N N   . SER A 1 119 ? 118.876 110.317 106.173 1.00 152.47 ? 119 SER A N   1 
ATOM 284  C CA  . SER A 1 119 ? 118.926 109.549 104.931 1.00 150.40 ? 119 SER A CA  1 
ATOM 285  C C   . SER A 1 119 ? 117.535 109.078 104.516 1.00 150.27 ? 119 SER A C   1 
ATOM 286  O O   . SER A 1 119 ? 117.145 109.198 103.348 1.00 149.41 ? 119 SER A O   1 
ATOM 287  C CB  . SER A 1 119 ? 119.872 108.360 105.089 1.00 149.63 ? 119 SER A CB  1 
ATOM 288  O OG  . SER A 1 119 ? 121.161 108.786 105.491 1.00 154.35 ? 119 SER A OG  1 
ATOM 289  N N   . LEU A 1 120 ? 116.769 108.537 105.466 1.00 151.27 ? 120 LEU A N   1 
ATOM 290  C CA  . LEU A 1 120 ? 115.418 108.075 105.158 1.00 152.02 ? 120 LEU A CA  1 
ATOM 291  C C   . LEU A 1 120 ? 114.526 109.236 104.725 1.00 151.63 ? 120 LEU A C   1 
ATOM 292  O O   . LEU A 1 120 ? 113.787 109.138 103.735 1.00 150.49 ? 120 LEU A O   1 
ATOM 293  C CB  . LEU A 1 120 ? 114.835 107.348 106.374 1.00 153.12 ? 120 LEU A CB  1 
ATOM 294  C CG  . LEU A 1 120 ? 113.379 106.866 106.431 1.00 155.03 ? 120 LEU A CG  1 
ATOM 295  C CD1 . LEU A 1 120 ? 112.394 107.975 106.805 1.00 151.60 ? 120 LEU A CD1 1 
ATOM 296  C CD2 . LEU A 1 120 ? 112.978 106.203 105.118 1.00 158.29 ? 120 LEU A CD2 1 
ATOM 297  N N   . PHE A 1 121 ? 114.583 110.348 105.462 1.00 152.13 ? 121 PHE A N   1 
ATOM 298  C CA  . PHE A 1 121 ? 113.776 111.511 105.112 1.00 150.67 ? 121 PHE A CA  1 
ATOM 299  C C   . PHE A 1 121 ? 114.171 112.064 103.750 1.00 146.35 ? 121 PHE A C   1 
ATOM 300  O O   . PHE A 1 121 ? 113.312 112.486 102.969 1.00 145.75 ? 121 PHE A O   1 
ATOM 301  C CB  . PHE A 1 121 ? 113.912 112.586 106.188 1.00 152.79 ? 121 PHE A CB  1 
ATOM 302  C CG  . PHE A 1 121 ? 112.997 113.756 105.992 1.00 153.41 ? 121 PHE A CG  1 
ATOM 303  C CD1 . PHE A 1 121 ? 111.674 113.693 106.392 1.00 151.96 ? 121 PHE A CD1 1 
ATOM 304  C CD2 . PHE A 1 121 ? 113.461 114.924 105.411 1.00 152.80 ? 121 PHE A CD2 1 
ATOM 305  C CE1 . PHE A 1 121 ? 110.830 114.770 106.212 1.00 151.88 ? 121 PHE A CE1 1 
ATOM 306  C CE2 . PHE A 1 121 ? 112.622 116.005 105.231 1.00 150.97 ? 121 PHE A CE2 1 
ATOM 307  C CZ  . PHE A 1 121 ? 111.305 115.928 105.631 1.00 151.27 ? 121 PHE A CZ  1 
ATOM 308  N N   . SER A 1 122 ? 115.468 112.070 103.449 1.00 144.75 ? 122 SER A N   1 
ATOM 309  C CA  . SER A 1 122 ? 115.935 112.565 102.164 1.00 140.04 ? 122 SER A CA  1 
ATOM 310  C C   . SER A 1 122 ? 115.481 111.662 101.029 1.00 141.99 ? 122 SER A C   1 
ATOM 311  O O   . SER A 1 122 ? 115.161 112.147 99.942  1.00 140.65 ? 122 SER A O   1 
ATOM 312  C CB  . SER A 1 122 ? 117.456 112.691 102.179 1.00 138.38 ? 122 SER A CB  1 
ATOM 313  O OG  . SER A 1 122 ? 118.069 111.422 102.048 1.00 141.80 ? 122 SER A OG  1 
ATOM 314  N N   . LEU A 1 123 ? 115.455 110.347 101.253 1.00 142.75 ? 123 LEU A N   1 
ATOM 315  C CA  . LEU A 1 123 ? 114.910 109.445 100.241 1.00 141.84 ? 123 LEU A CA  1 
ATOM 316  C C   . LEU A 1 123 ? 113.427 109.720 100.012 1.00 140.67 ? 123 LEU A C   1 
ATOM 317  O O   . LEU A 1 123 ? 112.961 109.797 98.865  1.00 140.19 ? 123 LEU A O   1 
ATOM 318  C CB  . LEU A 1 123 ? 115.138 107.992 100.660 1.00 141.29 ? 123 LEU A CB  1 
ATOM 319  C CG  . LEU A 1 123 ? 114.738 106.888 99.679  1.00 141.16 ? 123 LEU A CG  1 
ATOM 320  C CD1 . LEU A 1 123 ? 115.715 105.728 99.773  1.00 142.04 ? 123 LEU A CD1 1 
ATOM 321  C CD2 . LEU A 1 123 ? 113.321 106.401 99.943  1.00 138.49 ? 123 LEU A CD2 1 
ATOM 322  N N   . TRP A 1 124 ? 112.671 109.883 101.103 1.00 139.74 ? 124 TRP A N   1 
ATOM 323  C CA  . TRP A 1 124 ? 111.244 110.164 100.975 1.00 139.12 ? 124 TRP A CA  1 
ATOM 324  C C   . TRP A 1 124 ? 110.991 111.494 100.279 1.00 139.32 ? 124 TRP A C   1 
ATOM 325  O O   . TRP A 1 124 ? 109.973 111.656 99.599  1.00 139.39 ? 124 TRP A O   1 
ATOM 326  C CB  . TRP A 1 124 ? 110.576 110.156 102.348 1.00 143.14 ? 124 TRP A CB  1 
ATOM 327  C CG  . TRP A 1 124 ? 109.149 110.602 102.305 1.00 147.94 ? 124 TRP A CG  1 
ATOM 328  C CD1 . TRP A 1 124 ? 108.066 109.850 101.956 1.00 150.02 ? 124 TRP A CD1 1 
ATOM 329  C CD2 . TRP A 1 124 ? 108.648 111.906 102.618 1.00 148.03 ? 124 TRP A CD2 1 
ATOM 330  N NE1 . TRP A 1 124 ? 106.921 110.606 102.034 1.00 151.65 ? 124 TRP A NE1 1 
ATOM 331  C CE2 . TRP A 1 124 ? 107.252 111.872 102.438 1.00 149.74 ? 124 TRP A CE2 1 
ATOM 332  C CE3 . TRP A 1 124 ? 109.245 113.099 103.034 1.00 144.66 ? 124 TRP A CE3 1 
ATOM 333  C CZ2 . TRP A 1 124 ? 106.444 112.984 102.660 1.00 146.81 ? 124 TRP A CZ2 1 
ATOM 334  C CZ3 . TRP A 1 124 ? 108.441 114.202 103.254 1.00 144.28 ? 124 TRP A CZ3 1 
ATOM 335  C CH2 . TRP A 1 124 ? 107.056 114.137 103.067 1.00 143.99 ? 124 TRP A CH2 1 
ATOM 336  N N   . LEU A 1 125 ? 111.887 112.462 100.455 1.00 140.61 ? 125 LEU A N   1 
ATOM 337  C CA  . LEU A 1 125 ? 111.759 113.721 99.732  1.00 136.42 ? 125 LEU A CA  1 
ATOM 338  C C   . LEU A 1 125 ? 112.198 113.587 98.281  1.00 136.44 ? 125 LEU A C   1 
ATOM 339  O O   . LEU A 1 125 ? 111.626 114.239 97.401  1.00 136.82 ? 125 LEU A O   1 
ATOM 340  C CB  . LEU A 1 125 ? 112.571 114.811 100.429 1.00 130.97 ? 125 LEU A CB  1 
ATOM 341  C CG  . LEU A 1 125 ? 111.753 115.812 101.242 1.00 127.79 ? 125 LEU A CG  1 
ATOM 342  C CD1 . LEU A 1 125 ? 112.638 116.927 101.768 1.00 126.74 ? 125 LEU A CD1 1 
ATOM 343  C CD2 . LEU A 1 125 ? 110.615 116.372 100.407 1.00 122.34 ? 125 LEU A CD2 1 
ATOM 344  N N   . SER A 1 126 ? 113.196 112.744 98.014  1.00 136.93 ? 126 SER A N   1 
ATOM 345  C CA  . SER A 1 126 ? 113.734 112.613 96.668  1.00 135.01 ? 126 SER A CA  1 
ATOM 346  C C   . SER A 1 126 ? 112.791 111.847 95.756  1.00 138.83 ? 126 SER A C   1 
ATOM 347  O O   . SER A 1 126 ? 112.823 112.042 94.536  1.00 137.51 ? 126 SER A O   1 
ATOM 348  C CB  . SER A 1 126 ? 115.099 111.929 96.715  1.00 132.40 ? 126 SER A CB  1 
ATOM 349  O OG  . SER A 1 126 ? 115.375 111.256 95.499  1.00 131.54 ? 126 SER A OG  1 
ATOM 350  N N   . THR A 1 127 ? 111.949 110.974 96.314  1.00 139.40 ? 127 THR A N   1 
ATOM 351  C CA  . THR A 1 127 ? 110.971 110.309 95.461  1.00 141.15 ? 127 THR A CA  1 
ATOM 352  C C   . THR A 1 127 ? 109.959 111.290 94.879  1.00 143.57 ? 127 THR A C   1 
ATOM 353  O O   . THR A 1 127 ? 109.264 110.946 93.917  1.00 147.20 ? 127 THR A O   1 
ATOM 354  C CB  . THR A 1 127 ? 110.238 109.204 96.224  1.00 146.72 ? 127 THR A CB  1 
ATOM 355  O OG1 . THR A 1 127 ? 109.464 108.425 95.304  1.00 156.46 ? 127 THR A OG1 1 
ATOM 356  C CG2 . THR A 1 127 ? 109.300 109.799 97.252  1.00 142.03 ? 127 THR A CG2 1 
ATOM 357  N N   . ARG A 1 128 ? 109.864 112.503 95.437  1.00 141.68 ? 128 ARG A N   1 
ATOM 358  C CA  . ARG A 1 128 ? 108.979 113.539 94.929  1.00 137.45 ? 128 ARG A CA  1 
ATOM 359  C C   . ARG A 1 128 ? 109.567 114.181 93.674  1.00 137.57 ? 128 ARG A C   1 
ATOM 360  O O   . ARG A 1 128 ? 110.788 114.253 93.518  1.00 137.13 ? 128 ARG A O   1 
ATOM 361  C CB  . ARG A 1 128 ? 108.750 114.609 95.991  1.00 130.84 ? 128 ARG A CB  1 
ATOM 362  C CG  . ARG A 1 128 ? 107.787 114.203 97.090  1.00 133.42 ? 128 ARG A CG  1 
ATOM 363  C CD  . ARG A 1 128 ? 107.770 115.235 98.204  1.00 136.73 ? 128 ARG A CD  1 
ATOM 364  N NE  . ARG A 1 128 ? 106.836 116.320 97.930  1.00 136.45 ? 128 ARG A NE  1 
ATOM 365  C CZ  . ARG A 1 128 ? 106.829 117.482 98.569  1.00 131.51 ? 128 ARG A CZ  1 
ATOM 366  N NH1 . ARG A 1 128 ? 107.706 117.752 99.522  1.00 122.34 ? 128 ARG A NH1 1 
ATOM 367  N NH2 . ARG A 1 128 ? 105.920 118.396 98.243  1.00 131.90 ? 128 ARG A NH2 1 
ATOM 368  N N   . PRO A 1 129 ? 108.720 114.659 92.767  1.00 136.76 ? 129 PRO A N   1 
ATOM 369  C CA  . PRO A 1 129 ? 109.217 115.290 91.542  1.00 132.04 ? 129 PRO A CA  1 
ATOM 370  C C   . PRO A 1 129 ? 109.713 116.706 91.803  1.00 127.52 ? 129 PRO A C   1 
ATOM 371  O O   . PRO A 1 129 ? 109.456 117.309 92.844  1.00 126.31 ? 129 PRO A O   1 
ATOM 372  C CB  . PRO A 1 129 ? 107.989 115.297 90.629  1.00 130.70 ? 129 PRO A CB  1 
ATOM 373  C CG  . PRO A 1 129 ? 106.842 115.366 91.570  1.00 134.49 ? 129 PRO A CG  1 
ATOM 374  C CD  . PRO A 1 129 ? 107.249 114.586 92.793  1.00 136.17 ? 129 PRO A CD  1 
ATOM 375  N N   . ALA A 1 130 ? 110.438 117.231 90.817  1.00 124.14 ? 130 ALA A N   1 
ATOM 376  C CA  . ALA A 1 130 ? 110.957 118.590 90.887  1.00 113.59 ? 130 ALA A CA  1 
ATOM 377  C C   . ALA A 1 130 ? 109.873 119.585 90.495  1.00 115.54 ? 130 ALA A C   1 
ATOM 378  O O   . ALA A 1 130 ? 109.176 119.394 89.494  1.00 118.73 ? 130 ALA A O   1 
ATOM 379  C CB  . ALA A 1 130 ? 112.172 118.743 89.975  1.00 102.63 ? 130 ALA A CB  1 
ATOM 380  N N   . THR A 1 131 ? 109.735 120.647 91.281  1.00 112.97 ? 131 THR A N   1 
ATOM 381  C CA  . THR A 1 131 ? 108.700 121.643 91.068  1.00 112.17 ? 131 THR A CA  1 
ATOM 382  C C   . THR A 1 131 ? 109.269 122.856 90.339  1.00 103.55 ? 131 THR A C   1 
ATOM 383  O O   . THR A 1 131 ? 110.457 122.929 90.020  1.00 98.52  ? 131 THR A O   1 
ATOM 384  C CB  . THR A 1 131 ? 108.072 122.059 92.400  1.00 109.61 ? 131 THR A CB  1 
ATOM 385  O OG1 . THR A 1 131 ? 109.098 122.506 93.295  1.00 104.00 ? 131 THR A OG1 1 
ATOM 386  C CG2 . THR A 1 131 ? 107.336 120.890 93.030  1.00 111.67 ? 131 THR A CG2 1 
ATOM 387  N N   . ARG A 1 132 ? 108.393 123.825 90.069  1.00 103.72 ? 132 ARG A N   1 
ATOM 388  C CA  . ARG A 1 132 ? 108.799 125.094 89.482  1.00 97.06  ? 132 ARG A CA  1 
ATOM 389  C C   . ARG A 1 132 ? 109.700 125.904 90.399  1.00 95.58  ? 132 ARG A C   1 
ATOM 390  O O   . ARG A 1 132 ? 110.379 126.818 89.922  1.00 99.65  ? 132 ARG A O   1 
ATOM 391  C CB  . ARG A 1 132 ? 107.564 125.916 89.122  1.00 97.96  ? 132 ARG A CB  1 
ATOM 392  C CG  . ARG A 1 132 ? 106.847 125.454 87.871  1.00 105.24 ? 132 ARG A CG  1 
ATOM 393  C CD  . ARG A 1 132 ? 105.387 125.935 87.734  1.00 112.59 ? 132 ARG A CD  1 
ATOM 394  N NE  . ARG A 1 132 ? 105.202 127.345 87.391  1.00 120.93 ? 132 ARG A NE  1 
ATOM 395  C CZ  . ARG A 1 132 ? 105.452 128.384 88.181  1.00 122.66 ? 132 ARG A CZ  1 
ATOM 396  N NH1 . ARG A 1 132 ? 105.742 128.234 89.462  1.00 120.21 ? 132 ARG A NH1 1 
ATOM 397  N NH2 . ARG A 1 132 ? 105.353 129.613 87.683  1.00 122.70 ? 132 ARG A NH2 1 
ATOM 398  N N   . THR A 1 133 ? 109.712 125.605 91.695  1.00 96.79  ? 133 THR A N   1 
ATOM 399  C CA  . THR A 1 133 ? 110.589 126.276 92.643  1.00 96.83  ? 133 THR A CA  1 
ATOM 400  C C   . THR A 1 133 ? 111.910 125.552 92.846  1.00 96.54  ? 133 THR A C   1 
ATOM 401  O O   . THR A 1 133 ? 112.955 126.204 92.915  1.00 95.47  ? 133 THR A O   1 
ATOM 402  C CB  . THR A 1 133 ? 109.886 126.427 93.995  1.00 102.09 ? 133 THR A CB  1 
ATOM 403  O OG1 . THR A 1 133 ? 108.753 127.292 93.853  1.00 105.34 ? 133 THR A OG1 1 
ATOM 404  C CG2 . THR A 1 133 ? 110.831 126.995 95.033  1.00 100.17 ? 133 THR A CG2 1 
ATOM 405  N N   . MET A 1 134 ? 111.894 124.229 92.931  1.00 95.79  ? 134 MET A N   1 
ATOM 406  C CA  . MET A 1 134 ? 113.103 123.431 93.105  1.00 92.04  ? 134 MET A CA  1 
ATOM 407  C C   . MET A 1 134 ? 113.381 122.744 91.771  1.00 94.83  ? 134 MET A C   1 
ATOM 408  O O   . MET A 1 134 ? 112.932 121.624 91.527  1.00 96.60  ? 134 MET A O   1 
ATOM 409  C CB  . MET A 1 134 ? 112.935 122.429 94.236  1.00 90.45  ? 134 MET A CB  1 
ATOM 410  C CG  . MET A 1 134 ? 112.845 123.070 95.605  1.00 90.50  ? 134 MET A CG  1 
ATOM 411  S SD  . MET A 1 134 ? 114.392 123.011 96.517  1.00 102.55 ? 134 MET A SD  1 
ATOM 412  C CE  . MET A 1 134 ? 114.033 124.166 97.835  1.00 94.17  ? 134 MET A CE  1 
ATOM 413  N N   . THR A 1 135 ? 114.126 123.432 90.905  1.00 92.56  ? 135 THR A N   1 
ATOM 414  C CA  . THR A 1 135 ? 114.372 122.932 89.558  1.00 88.53  ? 135 THR A CA  1 
ATOM 415  C C   . THR A 1 135 ? 115.267 121.703 89.540  1.00 89.85  ? 135 THR A C   1 
ATOM 416  O O   . THR A 1 135 ? 115.211 120.928 88.580  1.00 87.21  ? 135 THR A O   1 
ATOM 417  C CB  . THR A 1 135 ? 114.989 124.031 88.699  1.00 82.97  ? 135 THR A CB  1 
ATOM 418  O OG1 . THR A 1 135 ? 115.894 124.804 89.496  1.00 86.22  ? 135 THR A OG1 1 
ATOM 419  C CG2 . THR A 1 135 ? 113.908 124.942 88.148  1.00 79.80  ? 135 THR A CG2 1 
ATOM 420  N N   . PHE A 1 136 ? 116.093 121.510 90.563  1.00 92.07  ? 136 PHE A N   1 
ATOM 421  C CA  . PHE A 1 136 ? 116.967 120.351 90.653  1.00 88.69  ? 136 PHE A CA  1 
ATOM 422  C C   . PHE A 1 136 ? 116.366 119.217 91.466  1.00 92.95  ? 136 PHE A C   1 
ATOM 423  O O   . PHE A 1 136 ? 117.003 118.170 91.609  1.00 95.11  ? 136 PHE A O   1 
ATOM 424  C CB  . PHE A 1 136 ? 118.312 120.752 91.260  1.00 86.94  ? 136 PHE A CB  1 
ATOM 425  C CG  . PHE A 1 136 ? 119.261 121.356 90.275  1.00 88.49  ? 136 PHE A CG  1 
ATOM 426  C CD1 . PHE A 1 136 ? 119.842 120.580 89.292  1.00 87.43  ? 136 PHE A CD1 1 
ATOM 427  C CD2 . PHE A 1 136 ? 119.570 122.699 90.331  1.00 87.85  ? 136 PHE A CD2 1 
ATOM 428  C CE1 . PHE A 1 136 ? 120.714 121.134 88.386  1.00 79.93  ? 136 PHE A CE1 1 
ATOM 429  C CE2 . PHE A 1 136 ? 120.439 123.255 89.428  1.00 85.13  ? 136 PHE A CE2 1 
ATOM 430  C CZ  . PHE A 1 136 ? 121.013 122.473 88.454  1.00 80.47  ? 136 PHE A CZ  1 
ATOM 431  N N   . GLY A 1 137 ? 115.163 119.395 92.001  1.00 95.95  ? 137 GLY A N   1 
ATOM 432  C CA  . GLY A 1 137 ? 114.572 118.393 92.861  1.00 96.92  ? 137 GLY A CA  1 
ATOM 433  C C   . GLY A 1 137 ? 114.878 118.657 94.318  1.00 97.86  ? 137 GLY A C   1 
ATOM 434  O O   . GLY A 1 137 ? 115.045 119.811 94.720  1.00 99.30  ? 137 GLY A O   1 
ATOM 435  N N   . TRP A 1 138 ? 114.967 117.598 95.119  1.00 96.04  ? 138 TRP A N   1 
ATOM 436  C CA  . TRP A 1 138 ? 115.209 117.730 96.549  1.00 96.06  ? 138 TRP A CA  1 
ATOM 437  C C   . TRP A 1 138 ? 116.411 116.904 96.986  1.00 101.11 ? 138 TRP A C   1 
ATOM 438  O O   . TRP A 1 138 ? 116.417 116.342 98.081  1.00 110.02 ? 138 TRP A O   1 
ATOM 439  C CB  . TRP A 1 138 ? 113.973 117.326 97.349  1.00 105.61 ? 138 TRP A CB  1 
ATOM 440  C CG  . TRP A 1 138 ? 112.728 118.024 96.925  1.00 104.87 ? 138 TRP A CG  1 
ATOM 441  C CD1 . TRP A 1 138 ? 111.975 117.762 95.821  1.00 105.73 ? 138 TRP A CD1 1 
ATOM 442  C CD2 . TRP A 1 138 ? 112.081 119.100 97.607  1.00 101.22 ? 138 TRP A CD2 1 
ATOM 443  N NE1 . TRP A 1 138 ? 110.901 118.614 95.768  1.00 103.86 ? 138 TRP A NE1 1 
ATOM 444  C CE2 . TRP A 1 138 ? 110.943 119.445 96.856  1.00 101.48 ? 138 TRP A CE2 1 
ATOM 445  C CE3 . TRP A 1 138 ? 112.354 119.806 98.780  1.00 100.21 ? 138 TRP A CE3 1 
ATOM 446  C CZ2 . TRP A 1 138 ? 110.080 120.465 97.239  1.00 103.11 ? 138 TRP A CZ2 1 
ATOM 447  C CZ3 . TRP A 1 138 ? 111.499 120.817 99.158  1.00 105.33 ? 138 TRP A CZ3 1 
ATOM 448  C CH2 . TRP A 1 138 ? 110.375 121.138 98.391  1.00 106.46 ? 138 TRP A CH2 1 
ATOM 449  N N   . HIS A 1 139 ? 117.439 116.826 96.146  1.00 98.02  ? 139 HIS A N   1 
ATOM 450  C CA  . HIS A 1 139 ? 118.587 115.984 96.447  1.00 99.73  ? 139 HIS A CA  1 
ATOM 451  C C   . HIS A 1 139 ? 119.555 116.618 97.435  1.00 104.71 ? 139 HIS A C   1 
ATOM 452  O O   . HIS A 1 139 ? 120.471 115.933 97.898  1.00 107.79 ? 139 HIS A O   1 
ATOM 453  C CB  . HIS A 1 139 ? 119.321 115.629 95.158  1.00 95.48  ? 139 HIS A CB  1 
ATOM 454  C CG  . HIS A 1 139 ? 118.442 115.006 94.121  1.00 98.10  ? 139 HIS A CG  1 
ATOM 455  N ND1 . HIS A 1 139 ? 117.863 113.767 94.285  1.00 108.39 ? 139 HIS A ND1 1 
ATOM 456  C CD2 . HIS A 1 139 ? 118.038 115.453 92.910  1.00 101.49 ? 139 HIS A CD2 1 
ATOM 457  C CE1 . HIS A 1 139 ? 117.142 113.476 93.218  1.00 112.90 ? 139 HIS A CE1 1 
ATOM 458  N NE2 . HIS A 1 139 ? 117.231 114.483 92.368  1.00 106.89 ? 139 HIS A NE2 1 
ATOM 459  N N   . ARG A 1 140 ? 119.383 117.893 97.769  1.00 100.25 ? 140 ARG A N   1 
ATOM 460  C CA  . ARG A 1 140 ? 120.226 118.532 98.771  1.00 97.29  ? 140 ARG A CA  1 
ATOM 461  C C   . ARG A 1 140 ? 119.769 118.235 100.191 1.00 102.50 ? 140 ARG A C   1 
ATOM 462  O O   . ARG A 1 140 ? 120.439 118.653 101.145 1.00 103.99 ? 140 ARG A O   1 
ATOM 463  C CB  . ARG A 1 140 ? 120.261 120.042 98.542  1.00 94.31  ? 140 ARG A CB  1 
ATOM 464  C CG  . ARG A 1 140 ? 121.226 120.475 97.458  1.00 93.39  ? 140 ARG A CG  1 
ATOM 465  C CD  . ARG A 1 140 ? 122.605 120.734 98.030  1.00 90.25  ? 140 ARG A CD  1 
ATOM 466  N NE  . ARG A 1 140 ? 123.621 120.803 96.989  1.00 89.02  ? 140 ARG A NE  1 
ATOM 467  C CZ  . ARG A 1 140 ? 124.160 121.928 96.543  1.00 88.85  ? 140 ARG A CZ  1 
ATOM 468  N NH1 . ARG A 1 140 ? 123.798 123.105 97.022  1.00 88.84  ? 140 ARG A NH1 1 
ATOM 469  N NH2 . ARG A 1 140 ? 125.087 121.871 95.592  1.00 90.79  ? 140 ARG A NH2 1 
ATOM 470  N N   . SER A 1 141 ? 118.646 117.533 100.349 1.00 105.16 ? 141 SER A N   1 
ATOM 471  C CA  . SER A 1 141 ? 118.180 117.172 101.680 1.00 106.57 ? 141 SER A CA  1 
ATOM 472  C C   . SER A 1 141 ? 119.151 116.231 102.375 1.00 110.37 ? 141 SER A C   1 
ATOM 473  O O   . SER A 1 141 ? 119.293 116.290 103.599 1.00 111.40 ? 141 SER A O   1 
ATOM 474  C CB  . SER A 1 141 ? 116.792 116.542 101.600 1.00 111.33 ? 141 SER A CB  1 
ATOM 475  O OG  . SER A 1 141 ? 116.774 115.471 100.676 1.00 116.20 ? 141 SER A OG  1 
ATOM 476  N N   . GLU A 1 142 ? 119.830 115.361 101.622 1.00 107.36 ? 142 GLU A N   1 
ATOM 477  C CA  . GLU A 1 142 ? 120.850 114.506 102.220 1.00 106.50 ? 142 GLU A CA  1 
ATOM 478  C C   . GLU A 1 142 ? 121.935 115.342 102.886 1.00 109.35 ? 142 GLU A C   1 
ATOM 479  O O   . GLU A 1 142 ? 122.282 115.121 104.053 1.00 113.49 ? 142 GLU A O   1 
ATOM 480  C CB  . GLU A 1 142 ? 121.487 113.572 101.180 1.00 107.42 ? 142 GLU A CB  1 
ATOM 481  C CG  . GLU A 1 142 ? 120.640 112.457 100.522 1.00 115.06 ? 142 GLU A CG  1 
ATOM 482  C CD  . GLU A 1 142 ? 119.546 112.898 99.554  1.00 122.77 ? 142 GLU A CD  1 
ATOM 483  O OE1 . GLU A 1 142 ? 119.104 114.059 99.565  1.00 119.38 ? 142 GLU A OE1 1 
ATOM 484  O OE2 . GLU A 1 142 ? 119.117 112.043 98.752  1.00 129.36 ? 142 GLU A OE2 1 
ATOM 485  N N   . THR A 1 143 ? 122.483 116.310 102.150 1.00 106.77 ? 143 THR A N   1 
ATOM 486  C CA  . THR A 1 143 ? 123.545 117.145 102.696 1.00 103.23 ? 143 THR A CA  1 
ATOM 487  C C   . THR A 1 143 ? 123.042 117.987 103.859 1.00 104.60 ? 143 THR A C   1 
ATOM 488  O O   . THR A 1 143 ? 123.744 118.155 104.863 1.00 107.61 ? 143 THR A O   1 
ATOM 489  C CB  . THR A 1 143 ? 124.126 118.036 101.602 1.00 101.84 ? 143 THR A CB  1 
ATOM 490  O OG1 . THR A 1 143 ? 124.399 117.246 100.440 1.00 104.20 ? 143 THR A OG1 1 
ATOM 491  C CG2 . THR A 1 143 ? 125.410 118.685 102.078 1.00 100.77 ? 143 THR A CG2 1 
ATOM 492  N N   . LEU A 1 144 ? 121.829 118.529 103.742 1.00 104.99 ? 144 LEU A N   1 
ATOM 493  C CA  . LEU A 1 144 ? 121.289 119.338 104.829 1.00 104.26 ? 144 LEU A CA  1 
ATOM 494  C C   . LEU A 1 144 ? 121.088 118.506 106.090 1.00 105.79 ? 144 LEU A C   1 
ATOM 495  O O   . LEU A 1 144 ? 121.393 118.961 107.198 1.00 110.12 ? 144 LEU A O   1 
ATOM 496  C CB  . LEU A 1 144 ? 119.981 119.994 104.392 1.00 106.55 ? 144 LEU A CB  1 
ATOM 497  C CG  . LEU A 1 144 ? 120.123 121.217 103.481 1.00 99.63  ? 144 LEU A CG  1 
ATOM 498  C CD1 . LEU A 1 144 ? 118.933 122.137 103.649 1.00 105.19 ? 144 LEU A CD1 1 
ATOM 499  C CD2 . LEU A 1 144 ? 121.417 121.965 103.753 1.00 92.30  ? 144 LEU A CD2 1 
ATOM 500  N N   . GLY A 1 145 ? 120.590 117.277 105.942 1.00 103.40 ? 145 GLY A N   1 
ATOM 501  C CA  . GLY A 1 145 ? 120.424 116.412 107.096 1.00 107.29 ? 145 GLY A CA  1 
ATOM 502  C C   . GLY A 1 145 ? 121.745 116.005 107.717 1.00 109.21 ? 145 GLY A C   1 
ATOM 503  O O   . GLY A 1 145 ? 121.866 115.929 108.942 1.00 112.21 ? 145 GLY A O   1 
ATOM 504  N N   . ALA A 1 146 ? 122.752 115.732 106.884 1.00 107.08 ? 146 ALA A N   1 
ATOM 505  C CA  . ALA A 1 146 ? 124.073 115.416 107.418 1.00 107.47 ? 146 ALA A CA  1 
ATOM 506  C C   . ALA A 1 146 ? 124.644 116.594 108.195 1.00 107.45 ? 146 ALA A C   1 
ATOM 507  O O   . ALA A 1 146 ? 125.214 116.420 109.280 1.00 110.72 ? 146 ALA A O   1 
ATOM 508  C CB  . ALA A 1 146 ? 125.012 115.009 106.286 1.00 104.68 ? 146 ALA A CB  1 
ATOM 509  N N   . LEU A 1 147 ? 124.492 117.806 107.657 1.00 104.68 ? 147 LEU A N   1 
ATOM 510  C CA  . LEU A 1 147 ? 124.966 118.993 108.359 1.00 102.70 ? 147 LEU A CA  1 
ATOM 511  C C   . LEU A 1 147 ? 124.223 119.188 109.674 1.00 108.93 ? 147 LEU A C   1 
ATOM 512  O O   . LEU A 1 147 ? 124.829 119.548 110.689 1.00 111.30 ? 147 LEU A O   1 
ATOM 513  C CB  . LEU A 1 147 ? 124.812 120.221 107.466 1.00 101.23 ? 147 LEU A CB  1 
ATOM 514  C CG  . LEU A 1 147 ? 125.383 121.523 108.020 1.00 104.19 ? 147 LEU A CG  1 
ATOM 515  C CD1 . LEU A 1 147 ? 126.886 121.411 108.179 1.00 103.35 ? 147 LEU A CD1 1 
ATOM 516  C CD2 . LEU A 1 147 ? 125.026 122.684 107.114 1.00 102.80 ? 147 LEU A CD2 1 
ATOM 517  N N   . ALA A 1 148 ? 122.908 118.960 109.675 1.00 108.95 ? 148 ALA A N   1 
ATOM 518  C CA  . ALA A 1 148 ? 122.137 119.084 110.907 1.00 108.70 ? 148 ALA A CA  1 
ATOM 519  C C   . ALA A 1 148 ? 122.584 118.062 111.944 1.00 114.01 ? 148 ALA A C   1 
ATOM 520  O O   . ALA A 1 148 ? 122.685 118.377 113.136 1.00 121.40 ? 148 ALA A O   1 
ATOM 521  C CB  . ALA A 1 148 ? 120.646 118.930 110.610 1.00 107.39 ? 148 ALA A CB  1 
ATOM 522  N N   . SER A 1 149 ? 122.847 116.828 111.509 1.00 111.36 ? 149 SER A N   1 
ATOM 523  C CA  . SER A 1 149 ? 123.318 115.806 112.436 1.00 112.65 ? 149 SER A CA  1 
ATOM 524  C C   . SER A 1 149 ? 124.672 116.181 113.023 1.00 117.42 ? 149 SER A C   1 
ATOM 525  O O   . SER A 1 149 ? 124.908 116.001 114.224 1.00 121.62 ? 149 SER A O   1 
ATOM 526  C CB  . SER A 1 149 ? 123.388 114.452 111.731 1.00 116.97 ? 149 SER A CB  1 
ATOM 527  O OG  . SER A 1 149 ? 124.679 114.211 111.205 1.00 121.25 ? 149 SER A OG  1 
ATOM 528  N N   . VAL A 1 150 ? 125.573 116.714 112.196 1.00 116.42 ? 150 VAL A N   1 
ATOM 529  C CA  . VAL A 1 150 ? 126.872 117.147 112.706 1.00 114.03 ? 150 VAL A CA  1 
ATOM 530  C C   . VAL A 1 150 ? 126.702 118.291 113.700 1.00 116.72 ? 150 VAL A C   1 
ATOM 531  O O   . VAL A 1 150 ? 127.362 118.331 114.747 1.00 120.96 ? 150 VAL A O   1 
ATOM 532  C CB  . VAL A 1 150 ? 127.800 117.535 111.542 1.00 111.99 ? 150 VAL A CB  1 
ATOM 533  C CG1 . VAL A 1 150 ? 129.043 118.227 112.064 1.00 113.06 ? 150 VAL A CG1 1 
ATOM 534  C CG2 . VAL A 1 150 ? 128.175 116.304 110.739 1.00 110.55 ? 150 VAL A CG2 1 
ATOM 535  N N   . VAL A 1 151 ? 125.813 119.235 113.391 1.00 116.07 ? 151 VAL A N   1 
ATOM 536  C CA  . VAL A 1 151 ? 125.586 120.367 114.285 1.00 117.34 ? 151 VAL A CA  1 
ATOM 537  C C   . VAL A 1 151 ? 125.051 119.889 115.628 1.00 120.72 ? 151 VAL A C   1 
ATOM 538  O O   . VAL A 1 151 ? 125.472 120.370 116.686 1.00 122.57 ? 151 VAL A O   1 
ATOM 539  C CB  . VAL A 1 151 ? 124.642 121.386 113.621 1.00 119.82 ? 151 VAL A CB  1 
ATOM 540  C CG1 . VAL A 1 151 ? 123.857 122.160 114.668 1.00 122.75 ? 151 VAL A CG1 1 
ATOM 541  C CG2 . VAL A 1 151 ? 125.432 122.333 112.738 1.00 118.99 ? 151 VAL A CG2 1 
ATOM 542  N N   . SER A 1 152 ? 124.116 118.938 115.612 1.00 120.94 ? 152 SER A N   1 
ATOM 543  C CA  . SER A 1 152 ? 123.589 118.407 116.866 1.00 120.13 ? 152 SER A CA  1 
ATOM 544  C C   . SER A 1 152 ? 124.655 117.630 117.632 1.00 121.80 ? 152 SER A C   1 
ATOM 545  O O   . SER A 1 152 ? 124.690 117.656 118.871 1.00 124.72 ? 152 SER A O   1 
ATOM 546  C CB  . SER A 1 152 ? 122.371 117.528 116.591 1.00 122.56 ? 152 SER A CB  1 
ATOM 547  O OG  . SER A 1 152 ? 122.754 116.306 115.989 1.00 125.83 ? 152 SER A OG  1 
ATOM 548  N N   . LEU A 1 153 ? 125.531 116.925 116.917 1.00 123.35 ? 153 LEU A N   1 
ATOM 549  C CA  . LEU A 1 153 ? 126.616 116.233 117.599 1.00 123.53 ? 153 LEU A CA  1 
ATOM 550  C C   . LEU A 1 153 ? 127.535 117.223 118.300 1.00 121.61 ? 153 LEU A C   1 
ATOM 551  O O   . LEU A 1 153 ? 127.971 116.979 119.428 1.00 121.78 ? 153 LEU A O   1 
ATOM 552  C CB  . LEU A 1 153 ? 127.403 115.372 116.617 1.00 123.20 ? 153 LEU A CB  1 
ATOM 553  C CG  . LEU A 1 153 ? 128.449 114.496 117.302 1.00 124.92 ? 153 LEU A CG  1 
ATOM 554  C CD1 . LEU A 1 153 ? 127.831 113.746 118.470 1.00 128.00 ? 153 LEU A CD1 1 
ATOM 555  C CD2 . LEU A 1 153 ? 129.044 113.528 116.318 1.00 126.99 ? 153 LEU A CD2 1 
ATOM 556  N N   . TRP A 1 154 ? 127.835 118.349 117.651 1.00 120.72 ? 154 TRP A N   1 
ATOM 557  C CA  . TRP A 1 154 ? 128.651 119.371 118.305 1.00 119.21 ? 154 TRP A CA  1 
ATOM 558  C C   . TRP A 1 154 ? 127.903 120.042 119.455 1.00 120.40 ? 154 TRP A C   1 
ATOM 559  O O   . TRP A 1 154 ? 128.516 120.406 120.462 1.00 120.36 ? 154 TRP A O   1 
ATOM 560  C CB  . TRP A 1 154 ? 129.141 120.396 117.284 1.00 120.61 ? 154 TRP A CB  1 
ATOM 561  C CG  . TRP A 1 154 ? 130.169 119.843 116.338 1.00 124.21 ? 154 TRP A CG  1 
ATOM 562  C CD1 . TRP A 1 154 ? 130.074 118.706 115.593 1.00 125.66 ? 154 TRP A CD1 1 
ATOM 563  C CD2 . TRP A 1 154 ? 131.447 120.412 116.036 1.00 132.06 ? 154 TRP A CD2 1 
ATOM 564  N NE1 . TRP A 1 154 ? 131.213 118.527 114.850 1.00 129.66 ? 154 TRP A NE1 1 
ATOM 565  C CE2 . TRP A 1 154 ? 132.073 119.562 115.102 1.00 135.51 ? 154 TRP A CE2 1 
ATOM 566  C CE3 . TRP A 1 154 ? 132.125 121.557 116.464 1.00 136.34 ? 154 TRP A CE3 1 
ATOM 567  C CZ2 . TRP A 1 154 ? 133.342 119.821 114.590 1.00 142.14 ? 154 TRP A CZ2 1 
ATOM 568  C CZ3 . TRP A 1 154 ? 133.385 121.812 115.955 1.00 140.38 ? 154 TRP A CZ3 1 
ATOM 569  C CH2 . TRP A 1 154 ? 133.980 120.948 115.028 1.00 144.10 ? 154 TRP A CH2 1 
ATOM 570  N N   . MET A 1 155 ? 126.587 120.224 119.319 1.00 121.37 ? 155 MET A N   1 
ATOM 571  C CA  . MET A 1 155 ? 125.725 120.573 120.446 1.00 123.15 ? 155 MET A CA  1 
ATOM 572  C C   . MET A 1 155 ? 126.049 119.738 121.677 1.00 119.63 ? 155 MET A C   1 
ATOM 573  O O   . MET A 1 155 ? 126.494 120.252 122.718 1.00 119.25 ? 155 MET A O   1 
ATOM 574  C CB  . MET A 1 155 ? 124.261 120.343 120.046 1.00 129.68 ? 155 MET A CB  1 
ATOM 575  C CG  . MET A 1 155 ? 123.218 121.332 120.523 1.00 137.74 ? 155 MET A CG  1 
ATOM 576  S SD  . MET A 1 155 ? 123.646 123.059 120.413 1.00 157.94 ? 155 MET A SD  1 
ATOM 577  C CE  . MET A 1 155 ? 122.839 123.677 121.889 1.00 145.19 ? 155 MET A CE  1 
ATOM 578  N N   . VAL A 1 156 ? 125.831 118.429 121.546 1.00 119.37 ? 156 VAL A N   1 
ATOM 579  C CA  . VAL A 1 156 ? 126.006 117.529 122.682 1.00 116.32 ? 156 VAL A CA  1 
ATOM 580  C C   . VAL A 1 156 ? 127.454 117.524 123.149 1.00 115.70 ? 156 VAL A C   1 
ATOM 581  O O   . VAL A 1 156 ? 127.730 117.516 124.353 1.00 115.88 ? 156 VAL A O   1 
ATOM 582  C CB  . VAL A 1 156 ? 125.518 116.112 122.333 1.00 118.22 ? 156 VAL A CB  1 
ATOM 583  C CG1 . VAL A 1 156 ? 125.304 115.312 123.600 1.00 117.85 ? 156 VAL A CG1 1 
ATOM 584  C CG2 . VAL A 1 156 ? 124.226 116.183 121.554 1.00 121.11 ? 156 VAL A CG2 1 
ATOM 585  N N   . THR A 1 157 ? 128.400 117.522 122.208 1.00 116.00 ? 157 THR A N   1 
ATOM 586  C CA  . THR A 1 157 ? 129.809 117.454 122.577 1.00 115.21 ? 157 THR A CA  1 
ATOM 587  C C   . THR A 1 157 ? 130.234 118.678 123.376 1.00 118.72 ? 157 THR A C   1 
ATOM 588  O O   . THR A 1 157 ? 130.943 118.552 124.378 1.00 120.98 ? 157 THR A O   1 
ATOM 589  C CB  . THR A 1 157 ? 130.669 117.301 121.326 1.00 120.04 ? 157 THR A CB  1 
ATOM 590  O OG1 . THR A 1 157 ? 130.351 116.063 120.681 1.00 124.56 ? 157 THR A OG1 1 
ATOM 591  C CG2 . THR A 1 157 ? 132.145 117.309 121.687 1.00 121.17 ? 157 THR A CG2 1 
ATOM 592  N N   . GLY A 1 158 ? 129.805 119.870 122.960 1.00 119.45 ? 158 GLY A N   1 
ATOM 593  C CA  . GLY A 1 158 ? 130.140 121.066 123.712 1.00 117.31 ? 158 GLY A CA  1 
ATOM 594  C C   . GLY A 1 158 ? 129.489 121.096 125.080 1.00 115.37 ? 158 GLY A C   1 
ATOM 595  O O   . GLY A 1 158 ? 130.119 121.488 126.070 1.00 116.58 ? 158 GLY A O   1 
ATOM 596  N N   . ILE A 1 159 ? 128.223 120.679 125.161 1.00 113.31 ? 159 ILE A N   1 
ATOM 597  C CA  . ILE A 1 159 ? 127.553 120.647 126.459 1.00 111.37 ? 159 ILE A CA  1 
ATOM 598  C C   . ILE A 1 159 ? 128.289 119.707 127.406 1.00 114.44 ? 159 ILE A C   1 
ATOM 599  O O   . ILE A 1 159 ? 128.556 120.045 128.567 1.00 116.79 ? 159 ILE A O   1 
ATOM 600  C CB  . ILE A 1 159 ? 126.077 120.245 126.293 1.00 112.37 ? 159 ILE A CB  1 
ATOM 601  C CG1 . ILE A 1 159 ? 125.227 121.473 125.973 1.00 111.14 ? 159 ILE A CG1 1 
ATOM 602  C CG2 . ILE A 1 159 ? 125.559 119.568 127.550 1.00 113.15 ? 159 ILE A CG2 1 
ATOM 603  C CD1 . ILE A 1 159 ? 123.917 121.143 125.304 1.00 110.78 ? 159 ILE A CD1 1 
ATOM 604  N N   . LEU A 1 160 ? 128.653 118.521 126.914 1.00 115.30 ? 160 LEU A N   1 
ATOM 605  C CA  . LEU A 1 160 ? 129.366 117.557 127.743 1.00 115.52 ? 160 LEU A CA  1 
ATOM 606  C C   . LEU A 1 160 ? 130.765 118.040 128.092 1.00 118.50 ? 160 LEU A C   1 
ATOM 607  O O   . LEU A 1 160 ? 131.253 117.767 129.191 1.00 122.05 ? 160 LEU A O   1 
ATOM 608  C CB  . LEU A 1 160 ? 129.432 116.209 127.035 1.00 113.36 ? 160 LEU A CB  1 
ATOM 609  C CG  . LEU A 1 160 ? 128.069 115.580 126.764 1.00 111.20 ? 160 LEU A CG  1 
ATOM 610  C CD1 . LEU A 1 160 ? 128.231 114.184 126.199 1.00 115.30 ? 160 LEU A CD1 1 
ATOM 611  C CD2 . LEU A 1 160 ? 127.238 115.568 128.030 1.00 109.26 ? 160 LEU A CD2 1 
ATOM 612  N N   . LEU A 1 161 ? 131.426 118.747 127.175 1.00 117.45 ? 161 LEU A N   1 
ATOM 613  C CA  . LEU A 1 161 ? 132.736 119.315 127.468 1.00 118.96 ? 161 LEU A CA  1 
ATOM 614  C C   . LEU A 1 161 ? 132.649 120.300 128.623 1.00 125.19 ? 161 LEU A C   1 
ATOM 615  O O   . LEU A 1 161 ? 133.451 120.249 129.564 1.00 128.63 ? 161 LEU A O   1 
ATOM 616  C CB  . LEU A 1 161 ? 133.285 119.997 126.216 1.00 123.95 ? 161 LEU A CB  1 
ATOM 617  C CG  . LEU A 1 161 ? 134.390 119.292 125.433 1.00 127.99 ? 161 LEU A CG  1 
ATOM 618  C CD1 . LEU A 1 161 ? 135.708 119.410 126.155 1.00 130.20 ? 161 LEU A CD1 1 
ATOM 619  C CD2 . LEU A 1 161 ? 134.032 117.835 125.233 1.00 124.39 ? 161 LEU A CD2 1 
ATOM 620  N N   . TYR A 1 162 ? 131.663 121.197 128.574 1.00 126.56 ? 162 TYR A N   1 
ATOM 621  C CA  . TYR A 1 162 ? 131.489 122.157 129.658 1.00 128.98 ? 162 TYR A CA  1 
ATOM 622  C C   . TYR A 1 162 ? 131.158 121.452 130.968 1.00 128.56 ? 162 TYR A C   1 
ATOM 623  O O   . TYR A 1 162 ? 131.703 121.797 132.025 1.00 132.07 ? 162 TYR A O   1 
ATOM 624  C CB  . TYR A 1 162 ? 130.394 123.159 129.298 1.00 127.46 ? 162 TYR A CB  1 
ATOM 625  C CG  . TYR A 1 162 ? 129.786 123.849 130.494 1.00 127.97 ? 162 TYR A CG  1 
ATOM 626  C CD1 . TYR A 1 162 ? 130.536 124.719 131.272 1.00 127.64 ? 162 TYR A CD1 1 
ATOM 627  C CD2 . TYR A 1 162 ? 128.468 123.616 130.856 1.00 129.91 ? 162 TYR A CD2 1 
ATOM 628  C CE1 . TYR A 1 162 ? 129.986 125.349 132.366 1.00 132.52 ? 162 TYR A CE1 1 
ATOM 629  C CE2 . TYR A 1 162 ? 127.910 124.239 131.952 1.00 133.96 ? 162 TYR A CE2 1 
ATOM 630  C CZ  . TYR A 1 162 ? 128.674 125.104 132.704 1.00 136.25 ? 162 TYR A CZ  1 
ATOM 631  O OH  . TYR A 1 162 ? 128.121 125.727 133.797 1.00 136.48 ? 162 TYR A OH  1 
ATOM 632  N N   . LEU A 1 163 ? 130.270 120.456 130.916 1.00 123.13 ? 163 LEU A N   1 
ATOM 633  C CA  . LEU A 1 163 ? 129.891 119.745 132.131 1.00 120.54 ? 163 LEU A CA  1 
ATOM 634  C C   . LEU A 1 163 ? 131.083 119.021 132.744 1.00 124.93 ? 163 LEU A C   1 
ATOM 635  O O   . LEU A 1 163 ? 131.277 119.055 133.963 1.00 129.67 ? 163 LEU A O   1 
ATOM 636  C CB  . LEU A 1 163 ? 128.761 118.762 131.834 1.00 118.58 ? 163 LEU A CB  1 
ATOM 637  C CG  . LEU A 1 163 ? 127.385 119.371 131.568 1.00 119.02 ? 163 LEU A CG  1 
ATOM 638  C CD1 . LEU A 1 163 ? 126.299 118.318 131.709 1.00 121.61 ? 163 LEU A CD1 1 
ATOM 639  C CD2 . LEU A 1 163 ? 127.126 120.538 132.502 1.00 121.93 ? 163 LEU A CD2 1 
ATOM 640  N N   . ALA A 1 164 ? 131.896 118.366 131.914 1.00 124.46 ? 164 ALA A N   1 
ATOM 641  C CA  . ALA A 1 164 ? 133.071 117.669 132.421 1.00 128.23 ? 164 ALA A CA  1 
ATOM 642  C C   . ALA A 1 164 ? 134.091 118.644 132.991 1.00 135.92 ? 164 ALA A C   1 
ATOM 643  O O   . ALA A 1 164 ? 134.709 118.369 134.027 1.00 138.64 ? 164 ALA A O   1 
ATOM 644  C CB  . ALA A 1 164 ? 133.698 116.824 131.314 1.00 127.58 ? 164 ALA A CB  1 
ATOM 645  N N   . PHE A 1 165 ? 134.286 119.788 132.329 1.00 136.98 ? 165 PHE A N   1 
ATOM 646  C CA  . PHE A 1 165 ? 135.225 120.779 132.843 1.00 138.97 ? 165 PHE A CA  1 
ATOM 647  C C   . PHE A 1 165 ? 134.776 121.298 134.201 1.00 140.17 ? 165 PHE A C   1 
ATOM 648  O O   . PHE A 1 165 ? 135.599 121.492 135.103 1.00 143.85 ? 165 PHE A O   1 
ATOM 649  C CB  . PHE A 1 165 ? 135.373 121.928 131.847 1.00 141.40 ? 165 PHE A CB  1 
ATOM 650  C CG  . PHE A 1 165 ? 136.665 122.680 131.978 1.00 153.29 ? 165 PHE A CG  1 
ATOM 651  C CD1 . PHE A 1 165 ? 137.875 122.008 131.951 1.00 154.38 ? 165 PHE A CD1 1 
ATOM 652  C CD2 . PHE A 1 165 ? 136.673 124.057 132.119 1.00 157.13 ? 165 PHE A CD2 1 
ATOM 653  C CE1 . PHE A 1 165 ? 139.069 122.693 132.067 1.00 155.23 ? 165 PHE A CE1 1 
ATOM 654  C CE2 . PHE A 1 165 ? 137.864 124.750 132.235 1.00 159.84 ? 165 PHE A CE2 1 
ATOM 655  C CZ  . PHE A 1 165 ? 139.064 124.066 132.209 1.00 158.54 ? 165 PHE A CZ  1 
ATOM 656  N N   . VAL A 1 166 ? 133.473 121.531 134.366 1.00 139.14 ? 166 VAL A N   1 
ATOM 657  C CA  . VAL A 1 166 ? 132.954 121.926 135.672 1.00 139.73 ? 166 VAL A CA  1 
ATOM 658  C C   . VAL A 1 166 ? 133.168 120.814 136.691 1.00 139.86 ? 166 VAL A C   1 
ATOM 659  O O   . VAL A 1 166 ? 133.599 121.062 137.823 1.00 142.49 ? 166 VAL A O   1 
ATOM 660  C CB  . VAL A 1 166 ? 131.468 122.318 135.563 1.00 137.72 ? 166 VAL A CB  1 
ATOM 661  C CG1 . VAL A 1 166 ? 130.757 122.097 136.887 1.00 133.05 ? 166 VAL A CG1 1 
ATOM 662  C CG2 . VAL A 1 166 ? 131.342 123.765 135.136 1.00 138.53 ? 166 VAL A CG2 1 
ATOM 663  N N   . ARG A 1 167 ? 132.886 119.569 136.300 1.00 139.15 ? 167 ARG A N   1 
ATOM 664  C CA  . ARG A 1 167 ? 132.977 118.454 137.235 1.00 137.35 ? 167 ARG A CA  1 
ATOM 665  C C   . ARG A 1 167 ? 134.406 118.206 137.693 1.00 140.57 ? 167 ARG A C   1 
ATOM 666  O O   . ARG A 1 167 ? 134.620 117.713 138.805 1.00 141.09 ? 167 ARG A O   1 
ATOM 667  C CB  . ARG A 1 167 ? 132.412 117.186 136.600 1.00 133.61 ? 167 ARG A CB  1 
ATOM 668  C CG  . ARG A 1 167 ? 130.931 116.980 136.831 1.00 131.40 ? 167 ARG A CG  1 
ATOM 669  C CD  . ARG A 1 167 ? 130.557 115.524 136.647 1.00 132.12 ? 167 ARG A CD  1 
ATOM 670  N NE  . ARG A 1 167 ? 129.120 115.316 136.760 1.00 131.98 ? 167 ARG A NE  1 
ATOM 671  C CZ  . ARG A 1 167 ? 128.515 114.157 136.547 1.00 128.96 ? 167 ARG A CZ  1 
ATOM 672  N NH1 . ARG A 1 167 ? 129.196 113.074 136.216 1.00 126.91 ? 167 ARG A NH1 1 
ATOM 673  N NH2 . ARG A 1 167 ? 127.192 114.085 136.663 1.00 127.92 ? 167 ARG A NH2 1 
ATOM 674  N N   . LEU A 1 168 ? 135.393 118.523 136.855 1.00 142.73 ? 168 LEU A N   1 
ATOM 675  C CA  . LEU A 1 168 ? 136.777 118.246 137.224 1.00 145.87 ? 168 LEU A CA  1 
ATOM 676  C C   . LEU A 1 168 ? 137.239 119.151 138.360 1.00 149.34 ? 168 LEU A C   1 
ATOM 677  O O   . LEU A 1 168 ? 137.606 118.673 139.439 1.00 152.17 ? 168 LEU A O   1 
ATOM 678  C CB  . LEU A 1 168 ? 137.688 118.397 136.007 1.00 145.56 ? 168 LEU A CB  1 
ATOM 679  C CG  . LEU A 1 168 ? 138.090 117.077 135.350 1.00 144.99 ? 168 LEU A CG  1 
ATOM 680  C CD1 . LEU A 1 168 ? 138.855 117.334 134.068 1.00 143.58 ? 168 LEU A CD1 1 
ATOM 681  C CD2 . LEU A 1 168 ? 138.912 116.234 136.310 1.00 145.10 ? 168 LEU A CD2 1 
ATOM 682  N N   . LEU A 1 169 ? 137.227 120.467 138.137 1.00 149.16 ? 169 LEU A N   1 
ATOM 683  C CA  . LEU A 1 169 ? 137.750 121.384 139.145 1.00 151.04 ? 169 LEU A CA  1 
ATOM 684  C C   . LEU A 1 169 ? 136.826 121.464 140.357 1.00 152.50 ? 169 LEU A C   1 
ATOM 685  O O   . LEU A 1 169 ? 137.294 121.625 141.489 1.00 151.55 ? 169 LEU A O   1 
ATOM 686  C CB  . LEU A 1 169 ? 138.005 122.756 138.509 1.00 150.58 ? 169 LEU A CB  1 
ATOM 687  C CG  . LEU A 1 169 ? 136.929 123.778 138.117 1.00 149.00 ? 169 LEU A CG  1 
ATOM 688  C CD1 . LEU A 1 169 ? 136.301 124.478 139.309 1.00 148.43 ? 169 LEU A CD1 1 
ATOM 689  C CD2 . LEU A 1 169 ? 137.502 124.796 137.141 1.00 145.83 ? 169 LEU A CD2 1 
ATOM 690  N N   . HIS A 1 170 ? 135.516 121.347 140.145 1.00 152.08 ? 170 HIS A N   1 
ATOM 691  C CA  . HIS A 1 170 ? 134.563 121.200 141.247 1.00 152.17 ? 170 HIS A CA  1 
ATOM 692  C C   . HIS A 1 170 ? 134.360 119.710 141.485 1.00 152.35 ? 170 HIS A C   1 
ATOM 693  O O   . HIS A 1 170 ? 133.441 119.092 140.949 1.00 153.78 ? 170 HIS A O   1 
ATOM 694  C CB  . HIS A 1 170 ? 133.244 121.898 140.937 1.00 155.87 ? 170 HIS A CB  1 
ATOM 695  C CG  . HIS A 1 170 ? 133.105 123.247 141.571 1.00 160.74 ? 170 HIS A CG  1 
ATOM 696  N ND1 . HIS A 1 170 ? 133.668 124.385 141.038 1.00 161.32 ? 170 HIS A ND1 1 
ATOM 697  C CD2 . HIS A 1 170 ? 132.460 123.638 142.696 1.00 162.62 ? 170 HIS A CD2 1 
ATOM 698  C CE1 . HIS A 1 170 ? 133.380 125.420 141.806 1.00 162.51 ? 170 HIS A CE1 1 
ATOM 699  N NE2 . HIS A 1 170 ? 132.647 124.994 142.819 1.00 162.83 ? 170 HIS A NE2 1 
ATOM 700  N N   . SER A 1 171 ? 135.227 119.125 142.310 1.00 150.37 ? 171 SER A N   1 
ATOM 701  C CA  . SER A 1 171 ? 135.187 117.685 142.570 1.00 150.64 ? 171 SER A CA  1 
ATOM 702  C C   . SER A 1 171 ? 134.207 117.391 143.706 1.00 152.47 ? 171 SER A C   1 
ATOM 703  O O   . SER A 1 171 ? 134.571 116.959 144.801 1.00 154.60 ? 171 SER A O   1 
ATOM 704  C CB  . SER A 1 171 ? 136.583 117.164 142.884 1.00 148.17 ? 171 SER A CB  1 
ATOM 705  O OG  . SER A 1 171 ? 137.560 117.854 142.127 1.00 148.83 ? 171 SER A OG  1 
ATOM 706  N N   . ASP A 1 172 ? 132.928 117.635 143.419 1.00 153.11 ? 172 ASP A N   1 
ATOM 707  C CA  . ASP A 1 172 ? 131.846 117.361 144.369 1.00 153.33 ? 172 ASP A CA  1 
ATOM 708  C C   . ASP A 1 172 ? 130.667 116.826 143.558 1.00 148.98 ? 172 ASP A C   1 
ATOM 709  O O   . ASP A 1 172 ? 129.835 117.594 143.068 1.00 146.27 ? 172 ASP A O   1 
ATOM 710  C CB  . ASP A 1 172 ? 131.442 118.584 145.200 1.00 159.00 ? 172 ASP A CB  1 
ATOM 711  C CG  . ASP A 1 172 ? 131.435 119.897 144.408 1.00 161.75 ? 172 ASP A CG  1 
ATOM 712  O OD1 . ASP A 1 172 ? 130.782 120.848 144.888 1.00 169.06 ? 172 ASP A OD1 1 
ATOM 713  O OD2 . ASP A 1 172 ? 132.040 120.005 143.325 1.00 159.67 ? 172 ASP A OD2 1 
ATOM 714  N N   . TYR A 1 173 ? 130.602 115.505 143.426 1.00 146.39 ? 173 TYR A N   1 
ATOM 715  C CA  . TYR A 1 173 ? 129.489 114.857 142.749 1.00 142.11 ? 173 TYR A CA  1 
ATOM 716  C C   . TYR A 1 173 ? 129.438 113.401 143.182 1.00 142.32 ? 173 TYR A C   1 
ATOM 717  O O   . TYR A 1 173 ? 130.432 112.836 143.643 1.00 142.63 ? 173 TYR A O   1 
ATOM 718  C CB  . TYR A 1 173 ? 129.608 114.970 141.225 1.00 137.14 ? 173 TYR A CB  1 
ATOM 719  C CG  . TYR A 1 173 ? 130.962 114.577 140.682 1.00 138.34 ? 173 TYR A CG  1 
ATOM 720  C CD1 . TYR A 1 173 ? 131.232 113.266 140.319 1.00 136.75 ? 173 TYR A CD1 1 
ATOM 721  C CD2 . TYR A 1 173 ? 131.968 115.518 140.527 1.00 140.37 ? 173 TYR A CD2 1 
ATOM 722  C CE1 . TYR A 1 173 ? 132.466 112.904 139.821 1.00 133.64 ? 173 TYR A CE1 1 
ATOM 723  C CE2 . TYR A 1 173 ? 133.205 115.164 140.030 1.00 140.49 ? 173 TYR A CE2 1 
ATOM 724  C CZ  . TYR A 1 173 ? 133.448 113.857 139.680 1.00 134.31 ? 173 TYR A CZ  1 
ATOM 725  O OH  . TYR A 1 173 ? 134.681 113.505 139.185 1.00 131.50 ? 173 TYR A OH  1 
ATOM 726  N N   . HIS A 1 174 ? 128.264 112.801 143.026 1.00 138.86 ? 174 HIS A N   1 
ATOM 727  C CA  . HIS A 1 174 ? 128.035 111.414 143.407 1.00 141.43 ? 174 HIS A CA  1 
ATOM 728  C C   . HIS A 1 174 ? 127.822 110.587 142.149 1.00 144.10 ? 174 HIS A C   1 
ATOM 729  O O   . HIS A 1 174 ? 126.909 110.867 141.365 1.00 142.63 ? 174 HIS A O   1 
ATOM 730  C CB  . HIS A 1 174 ? 126.832 111.293 144.342 1.00 145.93 ? 174 HIS A CB  1 
ATOM 731  C CG  . HIS A 1 174 ? 126.267 109.909 144.420 1.00 151.28 ? 174 HIS A CG  1 
ATOM 732  N ND1 . HIS A 1 174 ? 125.036 109.578 143.897 1.00 152.54 ? 174 HIS A ND1 1 
ATOM 733  C CD2 . HIS A 1 174 ? 126.767 108.771 144.957 1.00 147.47 ? 174 HIS A CD2 1 
ATOM 734  C CE1 . HIS A 1 174 ? 124.800 108.296 144.112 1.00 150.04 ? 174 HIS A CE1 1 
ATOM 735  N NE2 . HIS A 1 174 ? 125.835 107.783 144.753 1.00 148.45 ? 174 HIS A NE2 1 
ATOM 736  N N   . ILE A 1 175 ? 128.663 109.573 141.961 1.00 145.44 ? 175 ILE A N   1 
ATOM 737  C CA  . ILE A 1 175 ? 128.581 108.668 140.822 1.00 141.31 ? 175 ILE A CA  1 
ATOM 738  C C   . ILE A 1 175 ? 128.631 107.242 141.346 1.00 143.00 ? 175 ILE A C   1 
ATOM 739  O O   . ILE A 1 175 ? 129.543 106.887 142.101 1.00 148.73 ? 175 ILE A O   1 
ATOM 740  C CB  . ILE A 1 175 ? 129.718 108.912 139.813 1.00 132.69 ? 175 ILE A CB  1 
ATOM 741  C CG1 . ILE A 1 175 ? 129.471 110.204 139.037 1.00 131.27 ? 175 ILE A CG1 1 
ATOM 742  C CG2 . ILE A 1 175 ? 129.850 107.740 138.860 1.00 130.34 ? 175 ILE A CG2 1 
ATOM 743  C CD1 . ILE A 1 175 ? 130.507 110.476 137.979 1.00 127.94 ? 175 ILE A CD1 1 
ATOM 744  N N   . GLU A 1 176 ? 127.658 106.428 140.949 1.00 140.21 ? 176 GLU A N   1 
ATOM 745  C CA  . GLU A 1 176 ? 127.599 105.032 141.349 1.00 144.00 ? 176 GLU A CA  1 
ATOM 746  C C   . GLU A 1 176 ? 127.549 104.150 140.109 1.00 144.45 ? 176 GLU A C   1 
ATOM 747  O O   . GLU A 1 176 ? 126.925 104.507 139.104 1.00 143.67 ? 176 GLU A O   1 
ATOM 748  C CB  . GLU A 1 176 ? 126.389 104.760 142.257 1.00 141.27 ? 176 GLU A CB  1 
ATOM 749  C CG  . GLU A 1 176 ? 125.102 104.386 141.539 1.00 141.68 ? 176 GLU A CG  1 
ATOM 750  C CD  . GLU A 1 176 ? 124.407 105.575 140.904 1.00 145.66 ? 176 GLU A CD  1 
ATOM 751  O OE1 . GLU A 1 176 ? 124.891 106.714 141.061 1.00 142.60 ? 176 GLU A OE1 1 
ATOM 752  O OE2 . GLU A 1 176 ? 123.367 105.366 140.246 1.00 149.59 ? 176 GLU A OE2 1 
ATOM 753  N N   . GLY A 1 177 ? 128.231 103.008 140.178 1.00 142.18 ? 177 GLY A N   1 
ATOM 754  C CA  . GLY A 1 177 ? 128.269 102.088 139.059 1.00 134.92 ? 177 GLY A CA  1 
ATOM 755  C C   . GLY A 1 177 ? 127.070 101.180 138.937 1.00 134.94 ? 177 GLY A C   1 
ATOM 756  O O   . GLY A 1 177 ? 126.924 100.511 137.908 1.00 134.11 ? 177 GLY A O   1 
ATOM 757  N N   . GLY A 1 178 ? 126.197 101.167 139.947 1.00 135.18 ? 178 GLY A N   1 
ATOM 758  C CA  . GLY A 1 178 ? 125.041 100.288 139.942 1.00 134.79 ? 178 GLY A CA  1 
ATOM 759  C C   . GLY A 1 178 ? 124.095 100.534 138.789 1.00 135.87 ? 178 GLY A C   1 
ATOM 760  O O   . GLY A 1 178 ? 123.245 99.685  138.503 1.00 138.36 ? 178 GLY A O   1 
ATOM 761  N N   . ALA A 1 179 ? 124.204 101.684 138.138 1.00 133.54 ? 179 ALA A N   1 
ATOM 762  C CA  . ALA A 1 179 ? 123.547 101.927 136.866 1.00 134.85 ? 179 ALA A CA  1 
ATOM 763  C C   . ALA A 1 179 ? 124.526 102.117 135.720 1.00 134.07 ? 179 ALA A C   1 
ATOM 764  O O   . ALA A 1 179 ? 124.189 101.789 134.579 1.00 135.78 ? 179 ALA A O   1 
ATOM 765  C CB  . ALA A 1 179 ? 122.638 103.162 136.957 1.00 136.59 ? 179 ALA A CB  1 
ATOM 766  N N   . MET A 1 180 ? 125.727 102.627 136.001 1.00 130.71 ? 180 MET A N   1 
ATOM 767  C CA  . MET A 1 180 ? 126.721 102.845 134.956 1.00 127.25 ? 180 MET A CA  1 
ATOM 768  C C   . MET A 1 180 ? 127.065 101.546 134.242 1.00 131.30 ? 180 MET A C   1 
ATOM 769  O O   . MET A 1 180 ? 127.109 101.496 133.008 1.00 134.41 ? 180 MET A O   1 
ATOM 770  C CB  . MET A 1 180 ? 127.978 103.466 135.564 1.00 125.88 ? 180 MET A CB  1 
ATOM 771  C CG  . MET A 1 180 ? 128.132 104.950 135.323 1.00 126.26 ? 180 MET A CG  1 
ATOM 772  S SD  . MET A 1 180 ? 129.865 105.446 135.334 1.00 126.27 ? 180 MET A SD  1 
ATOM 773  C CE  . MET A 1 180 ? 130.249 105.416 133.588 1.00 122.35 ? 180 MET A CE  1 
ATOM 774  N N   . LEU A 1 181 ? 127.312 100.482 135.007 1.00 130.75 ? 181 LEU A N   1 
ATOM 775  C CA  . LEU A 1 181 ? 127.717 99.217  134.406 1.00 128.75 ? 181 LEU A CA  1 
ATOM 776  C C   . LEU A 1 181 ? 126.618 98.658  133.511 1.00 135.09 ? 181 LEU A C   1 
ATOM 777  O O   . LEU A 1 181 ? 126.878 98.221  132.383 1.00 136.80 ? 181 LEU A O   1 
ATOM 778  C CB  . LEU A 1 181 ? 128.081 98.219  135.502 1.00 123.80 ? 181 LEU A CB  1 
ATOM 779  C CG  . LEU A 1 181 ? 128.940 97.039  135.065 1.00 118.83 ? 181 LEU A CG  1 
ATOM 780  C CD1 . LEU A 1 181 ? 130.276 97.550  134.584 1.00 115.61 ? 181 LEU A CD1 1 
ATOM 781  C CD2 . LEU A 1 181 ? 129.119 96.061  136.209 1.00 121.32 ? 181 LEU A CD2 1 
ATOM 782  N N   . LEU A 1 182 ? 125.376 98.676  133.998 1.00 133.68 ? 182 LEU A N   1 
ATOM 783  C CA  . LEU A 1 182 ? 124.270 98.127  133.222 1.00 131.50 ? 182 LEU A CA  1 
ATOM 784  C C   . LEU A 1 182 ? 124.013 98.943  131.963 1.00 133.23 ? 182 LEU A C   1 
ATOM 785  O O   . LEU A 1 182 ? 123.778 98.374  130.890 1.00 137.78 ? 182 LEU A O   1 
ATOM 786  C CB  . LEU A 1 182 ? 123.004 98.034  134.077 1.00 127.25 ? 182 LEU A CB  1 
ATOM 787  C CG  . LEU A 1 182 ? 122.961 97.088  135.287 1.00 131.37 ? 182 LEU A CG  1 
ATOM 788  C CD1 . LEU A 1 182 ? 123.205 95.653  134.841 1.00 131.55 ? 182 LEU A CD1 1 
ATOM 789  C CD2 . LEU A 1 182 ? 123.915 97.466  136.412 1.00 130.37 ? 182 LEU A CD2 1 
ATOM 790  N N   . THR A 1 183 ? 124.063 100.273 132.060 1.00 129.40 ? 183 THR A N   1 
ATOM 791  C CA  . THR A 1 183 ? 123.831 101.069 130.861 1.00 131.02 ? 183 THR A CA  1 
ATOM 792  C C   . THR A 1 183 ? 124.972 100.927 129.861 1.00 136.28 ? 183 THR A C   1 
ATOM 793  O O   . THR A 1 183 ? 124.729 100.923 128.650 1.00 142.48 ? 183 THR A O   1 
ATOM 794  C CB  . THR A 1 183 ? 123.612 102.535 131.217 1.00 130.08 ? 183 THR A CB  1 
ATOM 795  O OG1 . THR A 1 183 ? 122.884 102.624 132.445 1.00 134.36 ? 183 THR A OG1 1 
ATOM 796  C CG2 . THR A 1 183 ? 122.799 103.205 130.132 1.00 137.92 ? 183 THR A CG2 1 
ATOM 797  N N   . ALA A 1 184 ? 126.214 100.794 130.334 1.00 135.65 ? 184 ALA A N   1 
ATOM 798  C CA  . ALA A 1 184 ? 127.322 100.555 129.415 1.00 132.82 ? 184 ALA A CA  1 
ATOM 799  C C   . ALA A 1 184 ? 127.184 99.204  128.727 1.00 135.18 ? 184 ALA A C   1 
ATOM 800  O O   . ALA A 1 184 ? 127.492 99.071  127.536 1.00 139.69 ? 184 ALA A O   1 
ATOM 801  C CB  . ALA A 1 184 ? 128.652 100.648 130.157 1.00 129.85 ? 184 ALA A CB  1 
ATOM 802  N N   . SER A 1 185 ? 126.730 98.186  129.462 1.00 134.13 ? 185 SER A N   1 
ATOM 803  C CA  . SER A 1 185 ? 126.470 96.895  128.837 1.00 140.13 ? 185 SER A CA  1 
ATOM 804  C C   . SER A 1 185 ? 125.383 97.012  127.777 1.00 145.22 ? 185 SER A C   1 
ATOM 805  O O   . SER A 1 185 ? 125.511 96.463  126.675 1.00 149.11 ? 185 SER A O   1 
ATOM 806  C CB  . SER A 1 185 ? 126.076 95.871  129.899 1.00 139.99 ? 185 SER A CB  1 
ATOM 807  O OG  . SER A 1 185 ? 127.082 95.754  130.889 1.00 139.09 ? 185 SER A OG  1 
ATOM 808  N N   . ILE A 1 186 ? 124.306 97.731  128.092 1.00 142.55 ? 186 ILE A N   1 
ATOM 809  C CA  . ILE A 1 186 ? 123.247 97.941  127.110 1.00 142.13 ? 186 ILE A CA  1 
ATOM 810  C C   . ILE A 1 186 ? 123.811 98.624  125.872 1.00 144.36 ? 186 ILE A C   1 
ATOM 811  O O   . ILE A 1 186 ? 123.496 98.248  124.736 1.00 150.16 ? 186 ILE A O   1 
ATOM 812  C CB  . ILE A 1 186 ? 122.089 98.746  127.735 1.00 142.88 ? 186 ILE A CB  1 
ATOM 813  C CG1 . ILE A 1 186 ? 121.040 97.819  128.363 1.00 145.43 ? 186 ILE A CG1 1 
ATOM 814  C CG2 . ILE A 1 186 ? 121.437 99.654  126.705 1.00 149.16 ? 186 ILE A CG2 1 
ATOM 815  C CD1 . ILE A 1 186 ? 121.590 96.680  129.199 1.00 143.67 ? 186 ILE A CD1 1 
ATOM 816  N N   . ALA A 1 187 ? 124.682 99.614  126.075 1.00 141.52 ? 187 ALA A N   1 
ATOM 817  C CA  . ALA A 1 187 ? 125.286 100.324 124.954 1.00 141.29 ? 187 ALA A CA  1 
ATOM 818  C C   . ALA A 1 187 ? 126.134 99.397  124.096 1.00 146.14 ? 187 ALA A C   1 
ATOM 819  O O   . ALA A 1 187 ? 126.095 99.475  122.863 1.00 150.73 ? 187 ALA A O   1 
ATOM 820  C CB  . ALA A 1 187 ? 126.132 101.488 125.466 1.00 137.89 ? 187 ALA A CB  1 
ATOM 821  N N   . VAL A 1 188 ? 126.921 98.522  124.724 1.00 144.87 ? 188 VAL A N   1 
ATOM 822  C CA  . VAL A 1 188 ? 127.815 97.681  123.933 1.00 147.06 ? 188 VAL A CA  1 
ATOM 823  C C   . VAL A 1 188 ? 127.020 96.641  123.148 1.00 154.41 ? 188 VAL A C   1 
ATOM 824  O O   . VAL A 1 188 ? 127.334 96.360  121.984 1.00 157.83 ? 188 VAL A O   1 
ATOM 825  C CB  . VAL A 1 188 ? 128.912 97.042  124.809 1.00 144.37 ? 188 VAL A CB  1 
ATOM 826  C CG1 . VAL A 1 188 ? 128.346 96.039  125.788 1.00 143.86 ? 188 VAL A CG1 1 
ATOM 827  C CG2 . VAL A 1 188 ? 129.971 96.392  123.932 1.00 145.20 ? 188 VAL A CG2 1 
ATOM 828  N N   . CYS A 1 189 ? 125.966 96.068  123.744 1.00 155.18 ? 189 CYS A N   1 
ATOM 829  C CA  . CYS A 1 189 ? 125.138 95.150  122.958 1.00 156.40 ? 189 CYS A CA  1 
ATOM 830  C C   . CYS A 1 189 ? 124.390 95.879  121.847 1.00 155.33 ? 189 CYS A C   1 
ATOM 831  O O   . CYS A 1 189 ? 124.212 95.329  120.753 1.00 156.90 ? 189 CYS A O   1 
ATOM 832  C CB  . CYS A 1 189 ? 124.162 94.363  123.836 1.00 155.56 ? 189 CYS A CB  1 
ATOM 833  S SG  . CYS A 1 189 ? 124.691 93.975  125.510 1.00 162.61 ? 189 CYS A SG  1 
ATOM 834  N N   . ALA A 1 190 ? 123.949 97.115  122.094 1.00 153.47 ? 190 ALA A N   1 
ATOM 835  C CA  . ALA A 1 190 ? 123.310 97.882  121.029 1.00 153.74 ? 190 ALA A CA  1 
ATOM 836  C C   . ALA A 1 190 ? 124.277 98.138  119.883 1.00 157.62 ? 190 ALA A C   1 
ATOM 837  O O   . ALA A 1 190 ? 123.907 98.032  118.706 1.00 165.58 ? 190 ALA A O   1 
ATOM 838  C CB  . ALA A 1 190 ? 122.773 99.202  121.579 1.00 152.08 ? 190 ALA A CB  1 
ATOM 839  N N   . ASN A 1 191 ? 125.525 98.476  120.208 1.00 155.31 ? 191 ASN A N   1 
ATOM 840  C CA  . ASN A 1 191 ? 126.516 98.716  119.167 1.00 158.32 ? 191 ASN A CA  1 
ATOM 841  C C   . ASN A 1 191 ? 126.834 97.434  118.407 1.00 164.06 ? 191 ASN A C   1 
ATOM 842  O O   . ASN A 1 191 ? 127.033 97.463  117.188 1.00 167.61 ? 191 ASN A O   1 
ATOM 843  C CB  . ASN A 1 191 ? 127.780 99.313  119.776 1.00 154.65 ? 191 ASN A CB  1 
ATOM 844  C CG  . ASN A 1 191 ? 128.574 100.120 118.777 1.00 155.42 ? 191 ASN A CG  1 
ATOM 845  O OD1 . ASN A 1 191 ? 129.111 99.578  117.814 1.00 158.56 ? 191 ASN A OD1 1 
ATOM 846  N ND2 . ASN A 1 191 ? 128.653 101.426 118.999 1.00 152.40 ? 191 ASN A ND2 1 
ATOM 847  N N   . LEU A 1 192 ? 126.884 96.298  119.108 1.00 162.98 ? 192 LEU A N   1 
ATOM 848  C CA  . LEU A 1 192 ? 127.086 95.023  118.427 1.00 165.58 ? 192 LEU A CA  1 
ATOM 849  C C   . LEU A 1 192 ? 125.934 94.715  117.479 1.00 168.96 ? 192 LEU A C   1 
ATOM 850  O O   . LEU A 1 192 ? 126.149 94.229  116.362 1.00 172.58 ? 192 LEU A O   1 
ATOM 851  C CB  . LEU A 1 192 ? 127.251 93.898  119.449 1.00 162.79 ? 192 LEU A CB  1 
ATOM 852  C CG  . LEU A 1 192 ? 128.551 93.878  120.252 1.00 159.31 ? 192 LEU A CG  1 
ATOM 853  C CD1 . LEU A 1 192 ? 128.658 92.596  121.055 1.00 159.35 ? 192 LEU A CD1 1 
ATOM 854  C CD2 . LEU A 1 192 ? 129.741 94.024  119.324 1.00 159.61 ? 192 LEU A CD2 1 
ATOM 855  N N   . LEU A 1 193 ? 124.700 94.985  117.909 1.00 168.25 ? 193 LEU A N   1 
ATOM 856  C CA  . LEU A 1 193 ? 123.552 94.753  117.040 1.00 172.31 ? 193 LEU A CA  1 
ATOM 857  C C   . LEU A 1 193 ? 123.601 95.659  115.815 1.00 174.52 ? 193 LEU A C   1 
ATOM 858  O O   . LEU A 1 193 ? 123.276 95.229  114.703 1.00 178.56 ? 193 LEU A O   1 
ATOM 859  C CB  . LEU A 1 193 ? 122.254 94.946  117.829 1.00 173.96 ? 193 LEU A CB  1 
ATOM 860  C CG  . LEU A 1 193 ? 120.905 95.140  117.129 1.00 176.41 ? 193 LEU A CG  1 
ATOM 861  C CD1 . LEU A 1 193 ? 119.796 94.672  118.051 1.00 175.05 ? 193 LEU A CD1 1 
ATOM 862  C CD2 . LEU A 1 193 ? 120.660 96.591  116.745 1.00 173.80 ? 193 LEU A CD2 1 
ATOM 863  N N   . MET A 1 194 ? 124.000 96.920  115.999 1.00 172.59 ? 194 MET A N   1 
ATOM 864  C CA  . MET A 1 194 ? 124.133 97.812  114.850 1.00 172.48 ? 194 MET A CA  1 
ATOM 865  C C   . MET A 1 194 ? 125.241 97.351  113.911 1.00 176.85 ? 194 MET A C   1 
ATOM 866  O O   . MET A 1 194 ? 125.116 97.479  112.688 1.00 181.76 ? 194 MET A O   1 
ATOM 867  C CB  . MET A 1 194 ? 124.377 99.249  115.306 1.00 165.66 ? 194 MET A CB  1 
ATOM 868  C CG  . MET A 1 194 ? 123.124 99.971  115.765 1.00 161.15 ? 194 MET A CG  1 
ATOM 869  S SD  . MET A 1 194 ? 122.685 101.267 114.591 1.00 146.99 ? 194 MET A SD  1 
ATOM 870  C CE  . MET A 1 194 ? 121.207 101.951 115.330 1.00 150.34 ? 194 MET A CE  1 
ATOM 871  N N   . ALA A 1 195 ? 126.337 96.821  114.459 1.00 175.13 ? 195 ALA A N   1 
ATOM 872  C CA  . ALA A 1 195 ? 127.387 96.267  113.610 1.00 177.81 ? 195 ALA A CA  1 
ATOM 873  C C   . ALA A 1 195 ? 126.873 95.075  112.813 1.00 185.35 ? 195 ALA A C   1 
ATOM 874  O O   . ALA A 1 195 ? 127.189 94.924  111.626 1.00 187.46 ? 195 ALA A O   1 
ATOM 875  C CB  . ALA A 1 195 ? 128.593 95.867  114.458 1.00 172.66 ? 195 ALA A CB  1 
ATOM 876  N N   . PHE A 1 196 ? 126.076 94.216  113.453 1.00 185.91 ? 196 PHE A N   1 
ATOM 877  C CA  . PHE A 1 196 ? 125.465 93.095  112.745 1.00 186.58 ? 196 PHE A CA  1 
ATOM 878  C C   . PHE A 1 196 ? 124.549 93.587  111.631 1.00 187.43 ? 196 PHE A C   1 
ATOM 879  O O   . PHE A 1 196 ? 124.549 93.034  110.525 1.00 186.82 ? 196 PHE A O   1 
ATOM 880  C CB  . PHE A 1 196 ? 124.700 92.215  113.738 1.00 186.46 ? 196 PHE A CB  1 
ATOM 881  C CG  . PHE A 1 196 ? 123.390 91.688  113.215 1.00 190.19 ? 196 PHE A CG  1 
ATOM 882  C CD1 . PHE A 1 196 ? 123.353 90.735  112.207 1.00 191.00 ? 196 PHE A CD1 1 
ATOM 883  C CD2 . PHE A 1 196 ? 122.193 92.152  113.733 1.00 189.01 ? 196 PHE A CD2 1 
ATOM 884  C CE1 . PHE A 1 196 ? 122.147 90.257  111.731 1.00 190.25 ? 196 PHE A CE1 1 
ATOM 885  C CE2 . PHE A 1 196 ? 120.985 91.677  113.261 1.00 188.67 ? 196 PHE A CE2 1 
ATOM 886  C CZ  . PHE A 1 196 ? 120.962 90.728  112.259 1.00 190.21 ? 196 PHE A CZ  1 
ATOM 887  N N   . VAL A 1 197 ? 123.760 94.628  111.907 1.00 186.91 ? 197 VAL A N   1 
ATOM 888  C CA  . VAL A 1 197 ? 122.871 95.187  110.891 1.00 184.06 ? 197 VAL A CA  1 
ATOM 889  C C   . VAL A 1 197 ? 123.678 95.735  109.721 1.00 185.56 ? 197 VAL A C   1 
ATOM 890  O O   . VAL A 1 197 ? 123.328 95.525  108.552 1.00 184.43 ? 197 VAL A O   1 
ATOM 891  C CB  . VAL A 1 197 ? 121.964 96.266  111.513 1.00 179.51 ? 197 VAL A CB  1 
ATOM 892  C CG1 . VAL A 1 197 ? 121.469 97.236  110.449 1.00 174.24 ? 197 VAL A CG1 1 
ATOM 893  C CG2 . VAL A 1 197 ? 120.792 95.618  112.232 1.00 178.05 ? 197 VAL A CG2 1 
ATOM 894  N N   . LEU A 1 198 ? 124.774 96.439  110.015 1.00 187.56 ? 198 LEU A N   1 
ATOM 895  C CA  . LEU A 1 198 ? 125.635 96.952  108.955 1.00 188.71 ? 198 LEU A CA  1 
ATOM 896  C C   . LEU A 1 198 ? 126.217 95.813  108.127 1.00 191.28 ? 198 LEU A C   1 
ATOM 897  O O   . LEU A 1 198 ? 126.315 95.913  106.899 1.00 191.31 ? 198 LEU A O   1 
ATOM 898  C CB  . LEU A 1 198 ? 126.747 97.814  109.559 1.00 188.48 ? 198 LEU A CB  1 
ATOM 899  C CG  . LEU A 1 198 ? 127.779 98.510  108.660 1.00 185.62 ? 198 LEU A CG  1 
ATOM 900  C CD1 . LEU A 1 198 ? 128.985 97.621  108.359 1.00 182.84 ? 198 LEU A CD1 1 
ATOM 901  C CD2 . LEU A 1 198 ? 127.142 99.022  107.373 1.00 182.86 ? 198 LEU A CD2 1 
ATOM 902  N N   . HIS A 1 199 ? 126.613 94.727  108.784 1.00 191.83 ? 199 HIS A N   1 
ATOM 903  C CA  . HIS A 1 199 ? 127.104 93.542  108.088 1.00 191.18 ? 199 HIS A CA  1 
ATOM 904  C C   . HIS A 1 199 ? 126.044 92.978  107.146 1.00 188.46 ? 199 HIS A C   1 
ATOM 905  O O   . HIS A 1 199 ? 126.165 93.084  105.926 1.00 183.25 ? 199 HIS A O   1 
ATOM 906  C CB  . HIS A 1 199 ? 127.536 92.471  109.093 1.00 190.77 ? 199 HIS A CB  1 
ATOM 907  C CG  . HIS A 1 199 ? 127.529 91.081  108.536 1.00 193.13 ? 199 HIS A CG  1 
ATOM 908  N ND1 . HIS A 1 199 ? 126.410 90.276  108.557 1.00 192.44 ? 199 HIS A ND1 1 
ATOM 909  C CD2 . HIS A 1 199 ? 128.503 90.353  107.941 1.00 191.93 ? 199 HIS A CD2 1 
ATOM 910  C CE1 . HIS A 1 199 ? 126.696 89.113  108.000 1.00 189.90 ? 199 HIS A CE1 1 
ATOM 911  N NE2 . HIS A 1 199 ? 127.960 89.134  107.618 1.00 190.29 ? 199 HIS A NE2 1 
ATOM 912  N N   . VAL A 1 237 ? 136.285 103.382 107.841 1.00 175.50 ? 237 VAL A N   1 
ATOM 913  C CA  . VAL A 1 237 ? 134.946 103.327 108.409 1.00 180.00 ? 237 VAL A CA  1 
ATOM 914  C C   . VAL A 1 237 ? 135.056 103.504 109.923 1.00 181.77 ? 237 VAL A C   1 
ATOM 915  O O   . VAL A 1 237 ? 136.084 103.181 110.514 1.00 180.39 ? 237 VAL A O   1 
ATOM 916  C CB  . VAL A 1 237 ? 134.234 102.011 108.029 1.00 175.96 ? 237 VAL A CB  1 
ATOM 917  C CG1 . VAL A 1 237 ? 134.872 100.823 108.740 1.00 170.58 ? 237 VAL A CG1 1 
ATOM 918  C CG2 . VAL A 1 237 ? 132.741 102.101 108.301 1.00 171.94 ? 237 VAL A CG2 1 
ATOM 919  N N   . HIS A 1 238 ? 134.005 104.034 110.548 1.00 181.57 ? 238 HIS A N   1 
ATOM 920  C CA  . HIS A 1 238 ? 134.042 104.405 111.956 1.00 177.51 ? 238 HIS A CA  1 
ATOM 921  C C   . HIS A 1 238 ? 133.336 103.403 112.865 1.00 175.81 ? 238 HIS A C   1 
ATOM 922  O O   . HIS A 1 238 ? 133.192 103.667 114.063 1.00 172.27 ? 238 HIS A O   1 
ATOM 923  C CB  . HIS A 1 238 ? 133.442 105.802 112.140 1.00 174.04 ? 238 HIS A CB  1 
ATOM 924  C CG  . HIS A 1 238 ? 131.955 105.810 112.313 1.00 176.60 ? 238 HIS A CG  1 
ATOM 925  N ND1 . HIS A 1 238 ? 131.350 105.838 113.550 1.00 171.31 ? 238 HIS A ND1 1 
ATOM 926  C CD2 . HIS A 1 238 ? 130.952 105.794 111.404 1.00 177.95 ? 238 HIS A CD2 1 
ATOM 927  C CE1 . HIS A 1 238 ? 130.038 105.840 113.397 1.00 170.71 ? 238 HIS A CE1 1 
ATOM 928  N NE2 . HIS A 1 238 ? 129.770 105.813 112.104 1.00 176.44 ? 238 HIS A NE2 1 
ATOM 929  N N   . VAL A 1 239 ? 132.902 102.258 112.334 1.00 176.74 ? 239 VAL A N   1 
ATOM 930  C CA  . VAL A 1 239 ? 132.261 101.258 113.185 1.00 172.07 ? 239 VAL A CA  1 
ATOM 931  C C   . VAL A 1 239 ? 133.249 100.706 114.205 1.00 169.18 ? 239 VAL A C   1 
ATOM 932  O O   . VAL A 1 239 ? 132.906 100.520 115.379 1.00 165.74 ? 239 VAL A O   1 
ATOM 933  C CB  . VAL A 1 239 ? 131.639 100.138 112.334 1.00 172.61 ? 239 VAL A CB  1 
ATOM 934  C CG1 . VAL A 1 239 ? 130.573 99.409  113.132 1.00 167.65 ? 239 VAL A CG1 1 
ATOM 935  C CG2 . VAL A 1 239 ? 131.039 100.714 111.070 1.00 173.38 ? 239 VAL A CG2 1 
ATOM 936  N N   . LEU A 1 240 ? 134.484 100.428 113.782 1.00 172.68 ? 240 LEU A N   1 
ATOM 937  C CA  . LEU A 1 240 ? 135.477 99.938  114.732 1.00 172.06 ? 240 LEU A CA  1 
ATOM 938  C C   . LEU A 1 240 ? 135.820 100.999 115.770 1.00 170.08 ? 240 LEU A C   1 
ATOM 939  O O   . LEU A 1 240 ? 136.054 100.669 116.938 1.00 167.75 ? 240 LEU A O   1 
ATOM 940  C CB  . LEU A 1 240 ? 136.733 99.461  113.998 1.00 176.30 ? 240 LEU A CB  1 
ATOM 941  C CG  . LEU A 1 240 ? 137.904 100.419 113.765 1.00 176.89 ? 240 LEU A CG  1 
ATOM 942  C CD1 . LEU A 1 240 ? 139.153 99.644  113.375 1.00 175.56 ? 240 LEU A CD1 1 
ATOM 943  C CD2 . LEU A 1 240 ? 137.564 101.445 112.699 1.00 174.63 ? 240 LEU A CD2 1 
ATOM 944  N N   . GLY A 1 241 ? 135.834 102.273 115.373 1.00 170.10 ? 241 GLY A N   1 
ATOM 945  C CA  . GLY A 1 241 ? 136.014 103.334 116.349 1.00 165.57 ? 241 GLY A CA  1 
ATOM 946  C C   . GLY A 1 241 ? 134.880 103.388 117.353 1.00 160.48 ? 241 GLY A C   1 
ATOM 947  O O   . GLY A 1 241 ? 135.101 103.616 118.544 1.00 154.95 ? 241 GLY A O   1 
ATOM 948  N N   . ASP A 1 242 ? 133.649 103.179 116.883 1.00 162.33 ? 242 ASP A N   1 
ATOM 949  C CA  . ASP A 1 242 ? 132.510 103.139 117.794 1.00 155.77 ? 242 ASP A CA  1 
ATOM 950  C C   . ASP A 1 242 ? 132.619 101.971 118.764 1.00 149.96 ? 242 ASP A C   1 
ATOM 951  O O   . ASP A 1 242 ? 132.325 102.115 119.956 1.00 149.03 ? 242 ASP A O   1 
ATOM 952  C CB  . ASP A 1 242 ? 131.206 103.056 117.006 1.00 159.45 ? 242 ASP A CB  1 
ATOM 953  C CG  . ASP A 1 242 ? 130.461 104.368 116.990 1.00 159.45 ? 242 ASP A CG  1 
ATOM 954  O OD1 . ASP A 1 242 ? 131.129 105.420 117.015 1.00 156.41 ? 242 ASP A OD1 1 
ATOM 955  O OD2 . ASP A 1 242 ? 129.213 104.349 116.961 1.00 163.62 ? 242 ASP A OD2 1 
ATOM 956  N N   . LEU A 1 243 ? 133.032 100.802 118.270 1.00 151.20 ? 243 LEU A N   1 
ATOM 957  C CA  . LEU A 1 243 ? 133.234 99.661  119.158 1.00 150.09 ? 243 LEU A CA  1 
ATOM 958  C C   . LEU A 1 243 ? 134.303 99.963  120.198 1.00 147.42 ? 243 LEU A C   1 
ATOM 959  O O   . LEU A 1 243 ? 134.137 99.654  121.384 1.00 146.94 ? 243 LEU A O   1 
ATOM 960  C CB  . LEU A 1 243 ? 133.605 98.411  118.361 1.00 156.29 ? 243 LEU A CB  1 
ATOM 961  C CG  . LEU A 1 243 ? 132.473 97.483  117.910 1.00 157.23 ? 243 LEU A CG  1 
ATOM 962  C CD1 . LEU A 1 243 ? 131.579 97.138  119.089 1.00 151.39 ? 243 LEU A CD1 1 
ATOM 963  C CD2 . LEU A 1 243 ? 131.662 98.067  116.774 1.00 161.90 ? 243 LEU A CD2 1 
ATOM 964  N N   . LEU A 1 244 ? 135.410 100.574 119.772 1.00 148.46 ? 244 LEU A N   1 
ATOM 965  C CA  . LEU A 1 244 ? 136.473 100.907 120.714 1.00 149.93 ? 244 LEU A CA  1 
ATOM 966  C C   . LEU A 1 244 ? 135.985 101.900 121.762 1.00 147.57 ? 244 LEU A C   1 
ATOM 967  O O   . LEU A 1 244 ? 136.295 101.762 122.950 1.00 145.36 ? 244 LEU A O   1 
ATOM 968  C CB  . LEU A 1 244 ? 137.686 101.461 119.963 1.00 153.23 ? 244 LEU A CB  1 
ATOM 969  C CG  . LEU A 1 244 ? 138.995 101.689 120.731 1.00 155.04 ? 244 LEU A CG  1 
ATOM 970  C CD1 . LEU A 1 244 ? 139.081 103.100 121.313 1.00 151.07 ? 244 LEU A CD1 1 
ATOM 971  C CD2 . LEU A 1 244 ? 139.184 100.639 121.820 1.00 152.40 ? 244 LEU A CD2 1 
ATOM 972  N N   . GLN A 1 245 ? 135.217 102.905 121.341 1.00 144.57 ? 245 GLN A N   1 
ATOM 973  C CA  . GLN A 1 245 ? 134.732 103.907 122.284 1.00 136.89 ? 245 GLN A CA  1 
ATOM 974  C C   . GLN A 1 245 ? 133.744 103.297 123.272 1.00 133.53 ? 245 GLN A C   1 
ATOM 975  O O   . GLN A 1 245 ? 133.782 103.607 124.470 1.00 130.98 ? 245 GLN A O   1 
ATOM 976  C CB  . GLN A 1 245 ? 134.134 105.086 121.504 1.00 135.05 ? 245 GLN A CB  1 
ATOM 977  C CG  . GLN A 1 245 ? 133.447 106.194 122.307 1.00 130.90 ? 245 GLN A CG  1 
ATOM 978  C CD  . GLN A 1 245 ? 132.029 105.881 122.745 1.00 133.36 ? 245 GLN A CD  1 
ATOM 979  O OE1 . GLN A 1 245 ? 131.495 104.809 122.472 1.00 137.18 ? 245 GLN A OE1 1 
ATOM 980  N NE2 . GLN A 1 245 ? 131.408 106.832 123.431 1.00 128.80 ? 245 GLN A NE2 1 
ATOM 981  N N   . SER A 1 246 ? 132.862 102.417 122.794 1.00 133.77 ? 246 SER A N   1 
ATOM 982  C CA  . SER A 1 246 ? 131.925 101.755 123.694 1.00 126.24 ? 246 SER A CA  1 
ATOM 983  C C   . SER A 1 246 ? 132.654 100.851 124.676 1.00 128.25 ? 246 SER A C   1 
ATOM 984  O O   . SER A 1 246 ? 132.290 100.785 125.856 1.00 129.40 ? 246 SER A O   1 
ATOM 985  C CB  . SER A 1 246 ? 130.897 100.963 122.893 1.00 132.01 ? 246 SER A CB  1 
ATOM 986  O OG  . SER A 1 246 ? 130.258 101.792 121.939 1.00 139.96 ? 246 SER A OG  1 
ATOM 987  N N   . PHE A 1 247 ? 133.691 100.150 124.211 1.00 129.81 ? 247 PHE A N   1 
ATOM 988  C CA  . PHE A 1 247 ? 134.480 99.320  125.113 1.00 129.24 ? 247 PHE A CA  1 
ATOM 989  C C   . PHE A 1 247 ? 135.217 100.169 126.139 1.00 126.88 ? 247 PHE A C   1 
ATOM 990  O O   . PHE A 1 247 ? 135.359 99.765  127.296 1.00 126.31 ? 247 PHE A O   1 
ATOM 991  C CB  . PHE A 1 247 ? 135.458 98.459  124.320 1.00 133.68 ? 247 PHE A CB  1 
ATOM 992  C CG  . PHE A 1 247 ? 134.852 97.197  123.788 1.00 141.04 ? 247 PHE A CG  1 
ATOM 993  C CD1 . PHE A 1 247 ? 134.144 96.351  124.623 1.00 139.22 ? 247 PHE A CD1 1 
ATOM 994  C CD2 . PHE A 1 247 ? 134.990 96.855  122.455 1.00 149.53 ? 247 PHE A CD2 1 
ATOM 995  C CE1 . PHE A 1 247 ? 133.583 95.189  124.138 1.00 143.90 ? 247 PHE A CE1 1 
ATOM 996  C CE2 . PHE A 1 247 ? 134.432 95.693  121.964 1.00 153.50 ? 247 PHE A CE2 1 
ATOM 997  C CZ  . PHE A 1 247 ? 133.728 94.858  122.807 1.00 151.93 ? 247 PHE A CZ  1 
ATOM 998  N N   . GLY A 1 248 ? 135.695 101.345 125.735 1.00 126.95 ? 248 GLY A N   1 
ATOM 999  C CA  . GLY A 1 248 ? 136.321 102.238 126.695 1.00 129.56 ? 248 GLY A CA  1 
ATOM 1000 C C   . GLY A 1 248 ? 135.351 102.716 127.758 1.00 124.85 ? 248 GLY A C   1 
ATOM 1001 O O   . GLY A 1 248 ? 135.686 102.760 128.946 1.00 121.78 ? 248 GLY A O   1 
ATOM 1002 N N   . VAL A 1 249 ? 134.134 103.077 127.347 1.00 124.79 ? 249 VAL A N   1 
ATOM 1003 C CA  . VAL A 1 249 ? 133.118 103.477 128.318 1.00 116.60 ? 249 VAL A CA  1 
ATOM 1004 C C   . VAL A 1 249 ? 132.804 102.325 129.261 1.00 114.51 ? 249 VAL A C   1 
ATOM 1005 O O   . VAL A 1 249 ? 132.671 102.517 130.476 1.00 117.48 ? 249 VAL A O   1 
ATOM 1006 C CB  . VAL A 1 249 ? 131.852 103.981 127.605 1.00 119.64 ? 249 VAL A CB  1 
ATOM 1007 C CG1 . VAL A 1 249 ? 130.771 104.286 128.619 1.00 115.24 ? 249 VAL A CG1 1 
ATOM 1008 C CG2 . VAL A 1 249 ? 132.162 105.216 126.788 1.00 124.02 ? 249 VAL A CG2 1 
ATOM 1009 N N   . LEU A 1 250 ? 132.681 101.110 128.721 1.00 114.70 ? 250 LEU A N   1 
ATOM 1010 C CA  . LEU A 1 250 ? 132.407 99.955  129.569 1.00 112.37 ? 250 LEU A CA  1 
ATOM 1011 C C   . LEU A 1 250 ? 133.543 99.711  130.553 1.00 116.79 ? 250 LEU A C   1 
ATOM 1012 O O   . LEU A 1 250 ? 133.301 99.375  131.717 1.00 120.82 ? 250 LEU A O   1 
ATOM 1013 C CB  . LEU A 1 250 ? 132.165 98.714  128.714 1.00 108.78 ? 250 LEU A CB  1 
ATOM 1014 C CG  . LEU A 1 250 ? 131.631 97.502  129.477 1.00 108.23 ? 250 LEU A CG  1 
ATOM 1015 C CD1 . LEU A 1 250 ? 130.460 96.884  128.740 1.00 120.70 ? 250 LEU A CD1 1 
ATOM 1016 C CD2 . LEU A 1 250 ? 132.725 96.476  129.688 1.00 104.06 ? 250 LEU A CD2 1 
ATOM 1017 N N   . ALA A 1 251 ? 134.790 99.863  130.103 1.00 115.16 ? 251 ALA A N   1 
ATOM 1018 C CA  . ALA A 1 251 ? 135.926 99.686  131.001 1.00 115.88 ? 251 ALA A CA  1 
ATOM 1019 C C   . ALA A 1 251 ? 135.916 100.730 132.109 1.00 121.00 ? 251 ALA A C   1 
ATOM 1020 O O   . ALA A 1 251 ? 136.211 100.420 133.270 1.00 122.29 ? 251 ALA A O   1 
ATOM 1021 C CB  . ALA A 1 251 ? 137.232 99.747  130.213 1.00 114.90 ? 251 ALA A CB  1 
ATOM 1022 N N   . ALA A 1 252 ? 135.578 101.975 131.768 1.00 120.68 ? 252 ALA A N   1 
ATOM 1023 C CA  . ALA A 1 252 ? 135.460 103.009 132.792 1.00 117.53 ? 252 ALA A CA  1 
ATOM 1024 C C   . ALA A 1 252 ? 134.366 102.665 133.794 1.00 118.73 ? 252 ALA A C   1 
ATOM 1025 O O   . ALA A 1 252 ? 134.531 102.878 135.001 1.00 122.08 ? 252 ALA A O   1 
ATOM 1026 C CB  . ALA A 1 252 ? 135.190 104.366 132.145 1.00 117.22 ? 252 ALA A CB  1 
ATOM 1027 N N   . SER A 1 253 ? 133.237 102.138 133.313 1.00 117.56 ? 253 SER A N   1 
ATOM 1028 C CA  . SER A 1 253 ? 132.172 101.730 134.223 1.00 111.72 ? 253 SER A CA  1 
ATOM 1029 C C   . SER A 1 253 ? 132.633 100.614 135.148 1.00 114.56 ? 253 SER A C   1 
ATOM 1030 O O   . SER A 1 253 ? 132.329 100.627 136.346 1.00 121.11 ? 253 SER A O   1 
ATOM 1031 C CB  . SER A 1 253 ? 130.937 101.291 133.440 1.00 116.78 ? 253 SER A CB  1 
ATOM 1032 O OG  . SER A 1 253 ? 130.751 102.088 132.288 1.00 125.97 ? 253 SER A OG  1 
ATOM 1033 N N   . ILE A 1 254 ? 133.363 99.634  134.612 1.00 115.70 ? 254 ILE A N   1 
ATOM 1034 C CA  . ILE A 1 254 ? 133.869 98.552  135.453 1.00 115.24 ? 254 ILE A CA  1 
ATOM 1035 C C   . ILE A 1 254 ? 134.817 99.099  136.509 1.00 119.35 ? 254 ILE A C   1 
ATOM 1036 O O   . ILE A 1 254 ? 134.777 98.685  137.673 1.00 123.31 ? 254 ILE A O   1 
ATOM 1037 C CB  . ILE A 1 254 ? 134.547 97.459  134.606 1.00 112.76 ? 254 ILE A CB  1 
ATOM 1038 C CG1 . ILE A 1 254 ? 133.605 96.956  133.513 1.00 111.15 ? 254 ILE A CG1 1 
ATOM 1039 C CG2 . ILE A 1 254 ? 135.012 96.319  135.497 1.00 116.70 ? 254 ILE A CG2 1 
ATOM 1040 C CD1 . ILE A 1 254 ? 133.866 95.534  133.075 1.00 110.09 ? 254 ILE A CD1 1 
ATOM 1041 N N   . LEU A 1 255 ? 135.689 100.030 136.121 1.00 119.75 ? 255 LEU A N   1 
ATOM 1042 C CA  . LEU A 1 255 ? 136.623 100.601 137.086 1.00 125.47 ? 255 LEU A CA  1 
ATOM 1043 C C   . LEU A 1 255 ? 135.885 101.376 138.172 1.00 128.30 ? 255 LEU A C   1 
ATOM 1044 O O   . LEU A 1 255 ? 136.240 101.289 139.354 1.00 129.31 ? 255 LEU A O   1 
ATOM 1045 C CB  . LEU A 1 255 ? 137.647 101.483 136.364 1.00 124.83 ? 255 LEU A CB  1 
ATOM 1046 C CG  . LEU A 1 255 ? 138.693 102.331 137.105 1.00 126.99 ? 255 LEU A CG  1 
ATOM 1047 C CD1 . LEU A 1 255 ? 138.139 103.559 137.828 1.00 127.18 ? 255 LEU A CD1 1 
ATOM 1048 C CD2 . LEU A 1 255 ? 139.446 101.447 138.088 1.00 128.68 ? 255 LEU A CD2 1 
ATOM 1049 N N   . ILE A 1 256 ? 134.866 102.147 137.793 1.00 127.60 ? 256 ILE A N   1 
ATOM 1050 C CA  . ILE A 1 256 ? 134.135 102.945 138.774 1.00 123.98 ? 256 ILE A CA  1 
ATOM 1051 C C   . ILE A 1 256 ? 133.376 102.042 139.738 1.00 122.84 ? 256 ILE A C   1 
ATOM 1052 O O   . ILE A 1 256 ? 133.447 102.212 140.960 1.00 126.21 ? 256 ILE A O   1 
ATOM 1053 C CB  . ILE A 1 256 ? 133.191 103.933 138.066 1.00 122.43 ? 256 ILE A CB  1 
ATOM 1054 C CG1 . ILE A 1 256 ? 133.946 105.199 137.664 1.00 124.94 ? 256 ILE A CG1 1 
ATOM 1055 C CG2 . ILE A 1 256 ? 132.017 104.288 138.961 1.00 120.46 ? 256 ILE A CG2 1 
ATOM 1056 C CD1 . ILE A 1 256 ? 134.364 106.051 138.832 1.00 127.89 ? 256 ILE A CD1 1 
ATOM 1057 N N   . TYR A 1 257 ? 132.647 101.062 139.202 1.00 120.95 ? 257 TYR A N   1 
ATOM 1058 C CA  . TYR A 1 257 ? 131.826 100.205 140.050 1.00 123.14 ? 257 TYR A CA  1 
ATOM 1059 C C   . TYR A 1 257 ? 132.680 99.358  140.984 1.00 127.24 ? 257 TYR A C   1 
ATOM 1060 O O   . TYR A 1 257 ? 132.338 99.186  142.159 1.00 131.05 ? 257 TYR A O   1 
ATOM 1061 C CB  . TYR A 1 257 ? 130.935 99.318  139.183 1.00 122.69 ? 257 TYR A CB  1 
ATOM 1062 C CG  . TYR A 1 257 ? 130.383 98.110  139.899 1.00 123.12 ? 257 TYR A CG  1 
ATOM 1063 C CD1 . TYR A 1 257 ? 129.490 98.248  140.949 1.00 126.14 ? 257 TYR A CD1 1 
ATOM 1064 C CD2 . TYR A 1 257 ? 130.753 96.830  139.519 1.00 126.86 ? 257 TYR A CD2 1 
ATOM 1065 C CE1 . TYR A 1 257 ? 128.982 97.144  141.604 1.00 128.63 ? 257 TYR A CE1 1 
ATOM 1066 C CE2 . TYR A 1 257 ? 130.251 95.720  140.167 1.00 130.49 ? 257 TYR A CE2 1 
ATOM 1067 C CZ  . TYR A 1 257 ? 129.366 95.882  141.208 1.00 131.90 ? 257 TYR A CZ  1 
ATOM 1068 O OH  . TYR A 1 257 ? 128.865 94.777  141.855 1.00 137.67 ? 257 TYR A OH  1 
ATOM 1069 N N   . PHE A 1 258 ? 133.792 98.821  140.482 1.00 126.71 ? 258 PHE A N   1 
ATOM 1070 C CA  . PHE A 1 258 ? 134.629 97.959  141.309 1.00 131.03 ? 258 PHE A CA  1 
ATOM 1071 C C   . PHE A 1 258 ? 135.347 98.751  142.393 1.00 133.15 ? 258 PHE A C   1 
ATOM 1072 O O   . PHE A 1 258 ? 135.445 98.298  143.539 1.00 133.50 ? 258 PHE A O   1 
ATOM 1073 C CB  . PHE A 1 258 ? 135.634 97.215  140.435 1.00 134.77 ? 258 PHE A CB  1 
ATOM 1074 C CG  . PHE A 1 258 ? 135.178 95.851  140.019 1.00 136.38 ? 258 PHE A CG  1 
ATOM 1075 C CD1 . PHE A 1 258 ? 133.879 95.439  140.259 1.00 134.78 ? 258 PHE A CD1 1 
ATOM 1076 C CD2 . PHE A 1 258 ? 136.047 94.980  139.387 1.00 137.93 ? 258 PHE A CD2 1 
ATOM 1077 C CE1 . PHE A 1 258 ? 133.454 94.184  139.877 1.00 138.10 ? 258 PHE A CE1 1 
ATOM 1078 C CE2 . PHE A 1 258 ? 135.630 93.722  139.002 1.00 141.22 ? 258 PHE A CE2 1 
ATOM 1079 C CZ  . PHE A 1 258 ? 134.331 93.323  139.247 1.00 143.88 ? 258 PHE A CZ  1 
ATOM 1080 N N   . LYS A 1 259 ? 135.851 99.937  142.054 1.00 132.89 ? 259 LYS A N   1 
ATOM 1081 C CA  . LYS A 1 259 ? 136.614 100.775 142.978 1.00 136.16 ? 259 LYS A CA  1 
ATOM 1082 C C   . LYS A 1 259 ? 135.920 102.124 143.090 1.00 137.47 ? 259 LYS A C   1 
ATOM 1083 O O   . LYS A 1 259 ? 136.240 103.063 142.345 1.00 140.24 ? 259 LYS A O   1 
ATOM 1084 C CB  . LYS A 1 259 ? 138.058 100.936 142.511 1.00 136.74 ? 259 LYS A CB  1 
ATOM 1085 C CG  . LYS A 1 259 ? 138.993 99.855  143.017 1.00 138.28 ? 259 LYS A CG  1 
ATOM 1086 C CD  . LYS A 1 259 ? 138.849 99.668  144.517 1.00 139.15 ? 259 LYS A CD  1 
ATOM 1087 C CE  . LYS A 1 259 ? 140.184 99.342  145.163 1.00 136.26 ? 259 LYS A CE  1 
ATOM 1088 N NZ  . LYS A 1 259 ? 140.442 97.877  145.194 1.00 128.58 ? 259 LYS A NZ  1 
ATOM 1089 N N   . PRO A 1 260 ? 134.965 102.268 144.010 1.00 137.89 ? 260 PRO A N   1 
ATOM 1090 C CA  . PRO A 1 260 ? 134.259 103.552 144.139 1.00 138.50 ? 260 PRO A CA  1 
ATOM 1091 C C   . PRO A 1 260 ? 135.155 104.699 144.559 1.00 136.67 ? 260 PRO A C   1 
ATOM 1092 O O   . PRO A 1 260 ? 134.783 105.860 144.350 1.00 133.30 ? 260 PRO A O   1 
ATOM 1093 C CB  . PRO A 1 260 ? 133.192 103.259 145.201 1.00 141.95 ? 260 PRO A CB  1 
ATOM 1094 C CG  . PRO A 1 260 ? 133.738 102.106 145.977 1.00 140.41 ? 260 PRO A CG  1 
ATOM 1095 C CD  . PRO A 1 260 ? 134.505 101.275 144.994 1.00 135.95 ? 260 PRO A CD  1 
ATOM 1096 N N   . GLN A 1 261 ? 136.321 104.415 145.144 1.00 137.90 ? 261 GLN A N   1 
ATOM 1097 C CA  . GLN A 1 261 ? 137.198 105.488 145.602 1.00 139.80 ? 261 GLN A CA  1 
ATOM 1098 C C   . GLN A 1 261 ? 137.660 106.355 144.439 1.00 140.46 ? 261 GLN A C   1 
ATOM 1099 O O   . GLN A 1 261 ? 137.764 107.580 144.573 1.00 138.91 ? 261 GLN A O   1 
ATOM 1100 C CB  . GLN A 1 261 ? 138.389 104.905 146.364 1.00 139.97 ? 261 GLN A CB  1 
ATOM 1101 C CG  . GLN A 1 261 ? 139.201 103.877 145.595 1.00 139.44 ? 261 GLN A CG  1 
ATOM 1102 C CD  . GLN A 1 261 ? 140.492 104.448 145.047 1.00 144.93 ? 261 GLN A CD  1 
ATOM 1103 O OE1 . GLN A 1 261 ? 140.584 105.639 144.757 1.00 147.19 ? 261 GLN A OE1 1 
ATOM 1104 N NE2 . GLN A 1 261 ? 141.502 103.598 144.909 1.00 146.21 ? 261 GLN A NE2 1 
ATOM 1105 N N   . TYR A 1 262 ? 137.945 105.744 143.294 1.00 139.92 ? 262 TYR A N   1 
ATOM 1106 C CA  . TYR A 1 262 ? 138.195 106.517 142.087 1.00 137.84 ? 262 TYR A CA  1 
ATOM 1107 C C   . TYR A 1 262 ? 136.906 107.192 141.643 1.00 136.80 ? 262 TYR A C   1 
ATOM 1108 O O   . TYR A 1 262 ? 135.834 106.581 141.663 1.00 136.09 ? 262 TYR A O   1 
ATOM 1109 C CB  . TYR A 1 262 ? 138.737 105.623 140.976 1.00 138.00 ? 262 TYR A CB  1 
ATOM 1110 C CG  . TYR A 1 262 ? 140.054 104.962 141.306 1.00 142.86 ? 262 TYR A CG  1 
ATOM 1111 C CD1 . TYR A 1 262 ? 141.173 105.720 141.619 1.00 143.36 ? 262 TYR A CD1 1 
ATOM 1112 C CD2 . TYR A 1 262 ? 140.180 103.580 141.300 1.00 142.42 ? 262 TYR A CD2 1 
ATOM 1113 C CE1 . TYR A 1 262 ? 142.380 105.120 141.921 1.00 144.59 ? 262 TYR A CE1 1 
ATOM 1114 C CE2 . TYR A 1 262 ? 141.382 102.972 141.599 1.00 143.34 ? 262 TYR A CE2 1 
ATOM 1115 C CZ  . TYR A 1 262 ? 142.479 103.746 141.908 1.00 144.98 ? 262 TYR A CZ  1 
ATOM 1116 O OH  . TYR A 1 262 ? 143.679 103.143 142.207 1.00 142.21 ? 262 TYR A OH  1 
ATOM 1117 N N   . LYS A 1 263 ? 137.007 108.460 141.257 1.00 135.02 ? 263 LYS A N   1 
ATOM 1118 C CA  . LYS A 1 263 ? 135.847 109.227 140.827 1.00 132.44 ? 263 LYS A CA  1 
ATOM 1119 C C   . LYS A 1 263 ? 136.076 110.037 139.564 1.00 128.68 ? 263 LYS A C   1 
ATOM 1120 O O   . LYS A 1 263 ? 135.098 110.351 138.876 1.00 130.27 ? 263 LYS A O   1 
ATOM 1121 C CB  . LYS A 1 263 ? 135.393 110.179 141.944 1.00 138.38 ? 263 LYS A CB  1 
ATOM 1122 C CG  . LYS A 1 263 ? 133.908 110.481 141.950 1.00 135.43 ? 263 LYS A CG  1 
ATOM 1123 C CD  . LYS A 1 263 ? 133.519 111.250 143.202 1.00 136.50 ? 263 LYS A CD  1 
ATOM 1124 C CE  . LYS A 1 263 ? 134.163 112.628 143.218 1.00 135.56 ? 263 LYS A CE  1 
ATOM 1125 N NZ  . LYS A 1 263 ? 133.157 113.724 143.217 1.00 138.31 ? 263 LYS A NZ  1 
ATOM 1126 N N   . ALA A 1 264 ? 137.316 110.377 139.229 1.00 126.30 ? 264 ALA A N   1 
ATOM 1127 C CA  . ALA A 1 264 ? 137.612 111.189 138.059 1.00 129.71 ? 264 ALA A CA  1 
ATOM 1128 C C   . ALA A 1 264 ? 137.646 110.381 136.772 1.00 129.96 ? 264 ALA A C   1 
ATOM 1129 O O   . ALA A 1 264 ? 138.054 110.913 135.734 1.00 128.12 ? 264 ALA A O   1 
ATOM 1130 C CB  . ALA A 1 264 ? 138.944 111.917 138.250 1.00 136.85 ? 264 ALA A CB  1 
ATOM 1131 N N   . ALA A 1 265 ? 137.243 109.110 136.819 1.00 128.30 ? 265 ALA A N   1 
ATOM 1132 C CA  . ALA A 1 265 ? 137.199 108.305 135.604 1.00 124.57 ? 265 ALA A CA  1 
ATOM 1133 C C   . ALA A 1 265 ? 136.169 108.845 134.623 1.00 121.45 ? 265 ALA A C   1 
ATOM 1134 O O   . ALA A 1 265 ? 136.404 108.860 133.411 1.00 124.30 ? 265 ALA A O   1 
ATOM 1135 C CB  . ALA A 1 265 ? 136.898 106.848 135.951 1.00 124.15 ? 265 ALA A CB  1 
ATOM 1136 N N   . ASP A 1 266 ? 135.024 109.295 135.127 1.00 117.22 ? 266 ASP A N   1 
ATOM 1137 C CA  . ASP A 1 266 ? 133.963 109.779 134.246 1.00 117.64 ? 266 ASP A CA  1 
ATOM 1138 C C   . ASP A 1 266 ? 134.375 110.974 133.393 1.00 122.18 ? 266 ASP A C   1 
ATOM 1139 O O   . ASP A 1 266 ? 134.217 110.905 132.161 1.00 127.70 ? 266 ASP A O   1 
ATOM 1140 C CB  . ASP A 1 266 ? 132.724 110.092 135.088 1.00 118.07 ? 266 ASP A CB  1 
ATOM 1141 C CG  . ASP A 1 266 ? 131.469 110.163 134.265 1.00 127.10 ? 266 ASP A CG  1 
ATOM 1142 O OD1 . ASP A 1 266 ? 131.341 109.382 133.301 1.00 128.69 ? 266 ASP A OD1 1 
ATOM 1143 O OD2 . ASP A 1 266 ? 130.609 111.005 134.589 1.00 132.12 ? 266 ASP A OD2 1 
ATOM 1144 N N   . PRO A 1 267 ? 134.900 112.076 133.947 1.00 120.36 ? 267 PRO A N   1 
ATOM 1145 C CA  . PRO A 1 267 ? 135.219 113.221 133.079 1.00 123.75 ? 267 PRO A CA  1 
ATOM 1146 C C   . PRO A 1 267 ? 136.312 112.938 132.065 1.00 127.14 ? 267 PRO A C   1 
ATOM 1147 O O   . PRO A 1 267 ? 136.221 113.409 130.925 1.00 129.92 ? 267 PRO A O   1 
ATOM 1148 C CB  . PRO A 1 267 ? 135.638 114.308 134.077 1.00 126.64 ? 267 PRO A CB  1 
ATOM 1149 C CG  . PRO A 1 267 ? 136.093 113.566 135.266 1.00 127.31 ? 267 PRO A CG  1 
ATOM 1150 C CD  . PRO A 1 267 ? 135.192 112.381 135.358 1.00 124.40 ? 267 PRO A CD  1 
ATOM 1151 N N   . ILE A 1 268 ? 137.351 112.188 132.439 1.00 122.64 ? 268 ILE A N   1 
ATOM 1152 C CA  . ILE A 1 268 ? 138.436 111.944 131.495 1.00 122.18 ? 268 ILE A CA  1 
ATOM 1153 C C   . ILE A 1 268 ? 137.941 111.119 130.313 1.00 120.92 ? 268 ILE A C   1 
ATOM 1154 O O   . ILE A 1 268 ? 138.267 111.415 129.155 1.00 123.16 ? 268 ILE A O   1 
ATOM 1155 C CB  . ILE A 1 268 ? 139.641 111.293 132.201 1.00 125.09 ? 268 ILE A CB  1 
ATOM 1156 C CG1 . ILE A 1 268 ? 139.274 109.941 132.811 1.00 120.74 ? 268 ILE A CG1 1 
ATOM 1157 C CG2 . ILE A 1 268 ? 140.186 112.221 133.274 1.00 125.11 ? 268 ILE A CG2 1 
ATOM 1158 C CD1 . ILE A 1 268 ? 140.382 108.915 132.728 1.00 111.00 ? 268 ILE A CD1 1 
ATOM 1159 N N   . SER A 1 269 ? 137.135 110.086 130.576 1.00 117.21 ? 269 SER A N   1 
ATOM 1160 C CA  . SER A 1 269 ? 136.547 109.323 129.483 1.00 116.67 ? 269 SER A CA  1 
ATOM 1161 C C   . SER A 1 269 ? 135.634 110.197 128.641 1.00 119.26 ? 269 SER A C   1 
ATOM 1162 O O   . SER A 1 269 ? 135.614 110.080 127.411 1.00 124.62 ? 269 SER A O   1 
ATOM 1163 C CB  . SER A 1 269 ? 135.787 108.113 130.019 1.00 113.05 ? 269 SER A CB  1 
ATOM 1164 O OG  . SER A 1 269 ? 136.446 107.551 131.134 1.00 120.83 ? 269 SER A OG  1 
ATOM 1165 N N   . THR A 1 270 ? 134.870 111.083 129.283 1.00 117.40 ? 270 THR A N   1 
ATOM 1166 C CA  . THR A 1 270 ? 134.052 112.017 128.519 1.00 119.12 ? 270 THR A CA  1 
ATOM 1167 C C   . THR A 1 270 ? 134.908 112.811 127.542 1.00 123.27 ? 270 THR A C   1 
ATOM 1168 O O   . THR A 1 270 ? 134.578 112.920 126.356 1.00 124.96 ? 270 THR A O   1 
ATOM 1169 C CB  . THR A 1 270 ? 133.302 112.954 129.461 1.00 117.51 ? 270 THR A CB  1 
ATOM 1170 O OG1 . THR A 1 270 ? 132.467 112.183 130.331 1.00 121.69 ? 270 THR A OG1 1 
ATOM 1171 C CG2 . THR A 1 270 ? 132.439 113.912 128.667 1.00 115.52 ? 270 THR A CG2 1 
ATOM 1172 N N   . PHE A 1 271 ? 136.032 113.347 128.021 1.00 123.15 ? 271 PHE A N   1 
ATOM 1173 C CA  . PHE A 1 271 ? 136.919 114.119 127.152 1.00 124.94 ? 271 PHE A CA  1 
ATOM 1174 C C   . PHE A 1 271 ? 137.429 113.276 125.988 1.00 123.29 ? 271 PHE A C   1 
ATOM 1175 O O   . PHE A 1 271 ? 137.317 113.674 124.819 1.00 127.19 ? 271 PHE A O   1 
ATOM 1176 C CB  . PHE A 1 271 ? 138.096 114.680 127.953 1.00 123.09 ? 271 PHE A CB  1 
ATOM 1177 C CG  . PHE A 1 271 ? 137.747 115.869 128.800 1.00 126.37 ? 271 PHE A CG  1 
ATOM 1178 C CD1 . PHE A 1 271 ? 137.778 115.787 130.179 1.00 130.35 ? 271 PHE A CD1 1 
ATOM 1179 C CD2 . PHE A 1 271 ? 137.402 117.075 128.218 1.00 127.86 ? 271 PHE A CD2 1 
ATOM 1180 C CE1 . PHE A 1 271 ? 137.457 116.876 130.959 1.00 132.87 ? 271 PHE A CE1 1 
ATOM 1181 C CE2 . PHE A 1 271 ? 137.086 118.171 128.999 1.00 131.54 ? 271 PHE A CE2 1 
ATOM 1182 C CZ  . PHE A 1 271 ? 137.113 118.070 130.369 1.00 133.77 ? 271 PHE A CZ  1 
ATOM 1183 N N   . LEU A 1 272 ? 137.995 112.102 126.288 1.00 116.61 ? 272 LEU A N   1 
ATOM 1184 C CA  . LEU A 1 272 ? 138.603 111.302 125.228 1.00 115.47 ? 272 LEU A CA  1 
ATOM 1185 C C   . LEU A 1 272 ? 137.576 110.879 124.187 1.00 120.93 ? 272 LEU A C   1 
ATOM 1186 O O   . LEU A 1 272 ? 137.836 110.962 122.981 1.00 127.87 ? 272 LEU A O   1 
ATOM 1187 C CB  . LEU A 1 272 ? 139.311 110.075 125.802 1.00 113.54 ? 272 LEU A CB  1 
ATOM 1188 C CG  . LEU A 1 272 ? 140.088 110.208 127.108 1.00 114.22 ? 272 LEU A CG  1 
ATOM 1189 C CD1 . LEU A 1 272 ? 140.561 108.851 127.590 1.00 109.45 ? 272 LEU A CD1 1 
ATOM 1190 C CD2 . LEU A 1 272 ? 141.260 111.153 126.932 1.00 117.15 ? 272 LEU A CD2 1 
ATOM 1191 N N   . PHE A 1 273 ? 136.398 110.439 124.621 1.00 118.24 ? 273 PHE A N   1 
ATOM 1192 C CA  . PHE A 1 273 ? 135.433 109.946 123.649 1.00 115.43 ? 273 PHE A CA  1 
ATOM 1193 C C   . PHE A 1 273 ? 134.719 111.073 122.914 1.00 118.59 ? 273 PHE A C   1 
ATOM 1194 O O   . PHE A 1 273 ? 134.317 110.888 121.759 1.00 125.47 ? 273 PHE A O   1 
ATOM 1195 C CB  . PHE A 1 273 ? 134.457 108.993 124.333 1.00 117.84 ? 273 PHE A CB  1 
ATOM 1196 C CG  . PHE A 1 273 ? 135.144 107.866 125.051 1.00 123.83 ? 273 PHE A CG  1 
ATOM 1197 C CD1 . PHE A 1 273 ? 136.135 107.138 124.417 1.00 124.51 ? 273 PHE A CD1 1 
ATOM 1198 C CD2 . PHE A 1 273 ? 134.799 107.526 126.345 1.00 124.61 ? 273 PHE A CD2 1 
ATOM 1199 C CE1 . PHE A 1 273 ? 136.779 106.105 125.064 1.00 125.83 ? 273 PHE A CE1 1 
ATOM 1200 C CE2 . PHE A 1 273 ? 135.442 106.492 126.997 1.00 121.58 ? 273 PHE A CE2 1 
ATOM 1201 C CZ  . PHE A 1 273 ? 136.430 105.780 126.356 1.00 123.14 ? 273 PHE A CZ  1 
ATOM 1202 N N   . SER A 1 274 ? 134.590 112.255 123.522 1.00 116.99 ? 274 SER A N   1 
ATOM 1203 C CA  . SER A 1 274 ? 134.123 113.409 122.762 1.00 122.81 ? 274 SER A CA  1 
ATOM 1204 C C   . SER A 1 274 ? 135.116 113.767 121.664 1.00 123.24 ? 274 SER A C   1 
ATOM 1205 O O   . SER A 1 274 ? 134.727 114.079 120.530 1.00 124.31 ? 274 SER A O   1 
ATOM 1206 C CB  . SER A 1 274 ? 133.901 114.595 123.698 1.00 122.23 ? 274 SER A CB  1 
ATOM 1207 O OG  . SER A 1 274 ? 132.860 114.329 124.619 1.00 126.71 ? 274 SER A OG  1 
ATOM 1208 N N   . ILE A 1 275 ? 136.411 113.718 121.985 1.00 120.32 ? 275 ILE A N   1 
ATOM 1209 C CA  . ILE A 1 275 ? 137.434 113.968 120.971 1.00 120.07 ? 275 ILE A CA  1 
ATOM 1210 C C   . ILE A 1 275 ? 137.349 112.921 119.867 1.00 121.90 ? 275 ILE A C   1 
ATOM 1211 O O   . ILE A 1 275 ? 137.484 113.234 118.677 1.00 125.81 ? 275 ILE A O   1 
ATOM 1212 C CB  . ILE A 1 275 ? 138.833 114.013 121.614 1.00 123.38 ? 275 ILE A CB  1 
ATOM 1213 C CG1 . ILE A 1 275 ? 139.186 115.430 122.090 1.00 127.65 ? 275 ILE A CG1 1 
ATOM 1214 C CG2 . ILE A 1 275 ? 139.895 113.500 120.651 1.00 122.69 ? 275 ILE A CG2 1 
ATOM 1215 C CD1 . ILE A 1 275 ? 138.081 116.179 122.805 1.00 126.23 ? 275 ILE A CD1 1 
ATOM 1216 N N   . CYS A 1 276 ? 137.122 111.664 120.245 1.00 120.96 ? 276 CYS A N   1 
ATOM 1217 C CA  . CYS A 1 276 ? 136.978 110.591 119.268 1.00 119.58 ? 276 CYS A CA  1 
ATOM 1218 C C   . CYS A 1 276 ? 135.810 110.859 118.330 1.00 119.95 ? 276 CYS A C   1 
ATOM 1219 O O   . CYS A 1 276 ? 135.934 110.687 117.115 1.00 124.31 ? 276 CYS A O   1 
ATOM 1220 C CB  . CYS A 1 276 ? 136.782 109.243 119.960 1.00 121.00 ? 276 CYS A CB  1 
ATOM 1221 S SG  . CYS A 1 276 ? 136.223 107.932 118.846 1.00 124.86 ? 276 CYS A SG  1 
ATOM 1222 N N   . ALA A 1 277 ? 134.675 111.281 118.884 1.00 118.12 ? 277 ALA A N   1 
ATOM 1223 C CA  . ALA A 1 277 ? 133.503 111.593 118.075 1.00 120.90 ? 277 ALA A CA  1 
ATOM 1224 C C   . ALA A 1 277 ? 133.790 112.726 117.099 1.00 124.05 ? 277 ALA A C   1 
ATOM 1225 O O   . ALA A 1 277 ? 133.462 112.634 115.908 1.00 128.41 ? 277 ALA A O   1 
ATOM 1226 C CB  . ALA A 1 277 ? 132.319 111.961 118.968 1.00 117.89 ? 277 ALA A CB  1 
ATOM 1227 N N   . LEU A 1 278 ? 134.404 113.802 117.597 1.00 120.59 ? 278 LEU A N   1 
ATOM 1228 C CA  . LEU A 1 278 ? 134.700 114.939 116.731 1.00 120.90 ? 278 LEU A CA  1 
ATOM 1229 C C   . LEU A 1 278 ? 135.646 114.544 115.604 1.00 122.52 ? 278 LEU A C   1 
ATOM 1230 O O   . LEU A 1 278 ? 135.429 114.906 114.440 1.00 123.45 ? 278 LEU A O   1 
ATOM 1231 C CB  . LEU A 1 278 ? 135.288 116.084 117.553 1.00 120.24 ? 278 LEU A CB  1 
ATOM 1232 C CG  . LEU A 1 278 ? 134.339 116.692 118.585 1.00 119.36 ? 278 LEU A CG  1 
ATOM 1233 C CD1 . LEU A 1 278 ? 134.921 117.966 119.167 1.00 122.09 ? 278 LEU A CD1 1 
ATOM 1234 C CD2 . LEU A 1 278 ? 132.981 116.960 117.963 1.00 120.39 ? 278 LEU A CD2 1 
ATOM 1235 N N   . GLY A 1 279 ? 136.694 113.787 115.927 1.00 124.49 ? 279 GLY A N   1 
ATOM 1236 C CA  . GLY A 1 279 ? 137.614 113.345 114.895 1.00 125.45 ? 279 GLY A CA  1 
ATOM 1237 C C   . GLY A 1 279 ? 136.962 112.413 113.893 1.00 127.90 ? 279 GLY A C   1 
ATOM 1238 O O   . GLY A 1 279 ? 137.285 112.440 112.704 1.00 131.15 ? 279 GLY A O   1 
ATOM 1239 N N   . SER A 1 280 ? 136.036 111.572 114.360 1.00 126.92 ? 280 SER A N   1 
ATOM 1240 C CA  . SER A 1 280 ? 135.379 110.632 113.461 1.00 125.88 ? 280 SER A CA  1 
ATOM 1241 C C   . SER A 1 280 ? 134.453 111.346 112.487 1.00 122.94 ? 280 SER A C   1 
ATOM 1242 O O   . SER A 1 280 ? 134.363 110.962 111.316 1.00 124.79 ? 280 SER A O   1 
ATOM 1243 C CB  . SER A 1 280 ? 134.610 109.586 114.264 1.00 129.86 ? 280 SER A CB  1 
ATOM 1244 O OG  . SER A 1 280 ? 133.358 110.091 114.692 1.00 132.42 ? 280 SER A OG  1 
ATOM 1245 N N   . THR A 1 281 ? 133.749 112.380 112.945 1.00 120.39 ? 281 THR A N   1 
ATOM 1246 C CA  . THR A 1 281 ? 132.813 113.085 112.075 1.00 121.87 ? 281 THR A CA  1 
ATOM 1247 C C   . THR A 1 281 ? 133.391 114.333 111.421 1.00 121.11 ? 281 THR A C   1 
ATOM 1248 O O   . THR A 1 281 ? 132.650 115.054 110.747 1.00 118.88 ? 281 THR A O   1 
ATOM 1249 C CB  . THR A 1 281 ? 131.540 113.448 112.839 1.00 124.18 ? 281 THR A CB  1 
ATOM 1250 O OG1 . THR A 1 281 ? 131.699 114.725 113.471 1.00 120.71 ? 281 THR A OG1 1 
ATOM 1251 C CG2 . THR A 1 281 ? 131.213 112.378 113.857 1.00 128.77 ? 281 THR A CG2 1 
ATOM 1252 N N   . ALA A 1 282 ? 134.678 114.617 111.606 1.00 122.81 ? 282 ALA A N   1 
ATOM 1253 C CA  . ALA A 1 282 ? 135.306 115.677 110.818 1.00 118.29 ? 282 ALA A CA  1 
ATOM 1254 C C   . ALA A 1 282 ? 135.231 115.442 109.310 1.00 116.52 ? 282 ALA A C   1 
ATOM 1255 O O   . ALA A 1 282 ? 134.874 116.386 108.582 1.00 120.49 ? 282 ALA A O   1 
ATOM 1256 C CB  . ALA A 1 282 ? 136.754 115.870 111.277 1.00 119.89 ? 282 ALA A CB  1 
ATOM 1257 N N   . PRO A 1 283 ? 135.567 114.259 108.769 1.00 114.98 ? 283 PRO A N   1 
ATOM 1258 C CA  . PRO A 1 283 ? 135.517 114.102 107.302 1.00 116.25 ? 283 PRO A CA  1 
ATOM 1259 C C   . PRO A 1 283 ? 134.136 114.306 106.705 1.00 114.36 ? 283 PRO A C   1 
ATOM 1260 O O   . PRO A 1 283 ? 134.016 114.845 105.596 1.00 115.20 ? 283 PRO A O   1 
ATOM 1261 C CB  . PRO A 1 283 ? 136.017 112.666 107.090 1.00 117.29 ? 283 PRO A CB  1 
ATOM 1262 C CG  . PRO A 1 283 ? 135.754 111.984 108.375 1.00 117.09 ? 283 PRO A CG  1 
ATOM 1263 C CD  . PRO A 1 283 ? 136.021 113.017 109.418 1.00 116.70 ? 283 PRO A CD  1 
ATOM 1264 N N   . THR A 1 284 ? 133.084 113.882 107.407 1.00 112.20 ? 284 THR A N   1 
ATOM 1265 C CA  . THR A 1 284 ? 131.732 114.129 106.921 1.00 111.67 ? 284 THR A CA  1 
ATOM 1266 C C   . THR A 1 284 ? 131.447 115.621 106.854 1.00 106.40 ? 284 THR A C   1 
ATOM 1267 O O   . THR A 1 284 ? 130.833 116.104 105.895 1.00 107.58 ? 284 THR A O   1 
ATOM 1268 C CB  . THR A 1 284 ? 130.715 113.425 107.818 1.00 113.70 ? 284 THR A CB  1 
ATOM 1269 O OG1 . THR A 1 284 ? 130.879 112.006 107.701 1.00 121.69 ? 284 THR A OG1 1 
ATOM 1270 C CG2 . THR A 1 284 ? 129.299 113.797 107.418 1.00 108.77 ? 284 THR A CG2 1 
ATOM 1271 N N   . LEU A 1 285 ? 131.896 116.369 107.862 1.00 105.48 ? 285 LEU A N   1 
ATOM 1272 C CA  . LEU A 1 285 ? 131.740 117.817 107.837 1.00 101.55 ? 285 LEU A CA  1 
ATOM 1273 C C   . LEU A 1 285 ? 132.480 118.416 106.650 1.00 105.53 ? 285 LEU A C   1 
ATOM 1274 O O   . LEU A 1 285 ? 131.968 119.322 105.986 1.00 109.91 ? 285 LEU A O   1 
ATOM 1275 C CB  . LEU A 1 285 ? 132.227 118.410 109.163 1.00 106.62 ? 285 LEU A CB  1 
ATOM 1276 C CG  . LEU A 1 285 ? 132.147 119.900 109.532 1.00 104.10 ? 285 LEU A CG  1 
ATOM 1277 C CD1 . LEU A 1 285 ? 132.983 120.828 108.656 1.00 106.07 ? 285 LEU A CD1 1 
ATOM 1278 C CD2 . LEU A 1 285 ? 130.693 120.345 109.528 1.00 99.82  ? 285 LEU A CD2 1 
ATOM 1279 N N   . ARG A 1 286 ? 133.686 117.921 106.367 1.00 107.90 ? 286 ARG A N   1 
ATOM 1280 C CA  . ARG A 1 286 ? 134.443 118.443 105.232 1.00 110.22 ? 286 ARG A CA  1 
ATOM 1281 C C   . ARG A 1 286 ? 133.725 118.174 103.913 1.00 107.53 ? 286 ARG A C   1 
ATOM 1282 O O   . ARG A 1 286 ? 133.637 119.059 103.051 1.00 107.87 ? 286 ARG A O   1 
ATOM 1283 C CB  . ARG A 1 286 ? 135.846 117.837 105.223 1.00 115.15 ? 286 ARG A CB  1 
ATOM 1284 C CG  . ARG A 1 286 ? 136.384 117.498 103.847 1.00 118.86 ? 286 ARG A CG  1 
ATOM 1285 C CD  . ARG A 1 286 ? 137.895 117.370 103.872 1.00 128.64 ? 286 ARG A CD  1 
ATOM 1286 N NE  . ARG A 1 286 ? 138.333 116.267 104.718 1.00 136.78 ? 286 ARG A NE  1 
ATOM 1287 C CZ  . ARG A 1 286 ? 138.442 115.008 104.315 1.00 135.67 ? 286 ARG A CZ  1 
ATOM 1288 N NH1 . ARG A 1 286 ? 138.144 114.651 103.077 1.00 133.60 ? 286 ARG A NH1 1 
ATOM 1289 N NH2 . ARG A 1 286 ? 138.860 114.085 105.175 1.00 134.61 ? 286 ARG A NH2 1 
ATOM 1290 N N   . ASP A 1 287 ? 133.197 116.960 103.741 1.00 105.98 ? 287 ASP A N   1 
ATOM 1291 C CA  . ASP A 1 287 ? 132.477 116.635 102.512 1.00 103.62 ? 287 ASP A CA  1 
ATOM 1292 C C   . ASP A 1 287 ? 131.226 117.490 102.363 1.00 100.67 ? 287 ASP A C   1 
ATOM 1293 O O   . ASP A 1 287 ? 130.929 117.989 101.269 1.00 99.17  ? 287 ASP A O   1 
ATOM 1294 C CB  . ASP A 1 287 ? 132.112 115.153 102.492 1.00 110.09 ? 287 ASP A CB  1 
ATOM 1295 C CG  . ASP A 1 287 ? 133.270 114.277 102.074 1.00 123.10 ? 287 ASP A CG  1 
ATOM 1296 O OD1 . ASP A 1 287 ? 134.346 114.827 101.762 1.00 127.22 ? 287 ASP A OD1 1 
ATOM 1297 O OD2 . ASP A 1 287 ? 133.108 113.039 102.058 1.00 127.17 ? 287 ASP A OD2 1 
ATOM 1298 N N   . VAL A 1 288 ? 130.480 117.669 103.453 1.00 102.78 ? 288 VAL A N   1 
ATOM 1299 C CA  . VAL A 1 288 ? 129.276 118.492 103.409 1.00 97.39  ? 288 VAL A CA  1 
ATOM 1300 C C   . VAL A 1 288 ? 129.631 119.929 103.059 1.00 96.95  ? 288 VAL A C   1 
ATOM 1301 O O   . VAL A 1 288 ? 128.940 120.581 102.267 1.00 98.01  ? 288 VAL A O   1 
ATOM 1302 C CB  . VAL A 1 288 ? 128.525 118.399 104.750 1.00 96.83  ? 288 VAL A CB  1 
ATOM 1303 C CG1 . VAL A 1 288 ? 127.663 119.625 104.972 1.00 98.59  ? 288 VAL A CG1 1 
ATOM 1304 C CG2 . VAL A 1 288 ? 127.686 117.137 104.795 1.00 98.72  ? 288 VAL A CG2 1 
ATOM 1305 N N   . LEU A 1 289 ? 130.713 120.445 103.644 1.00 98.12  ? 289 LEU A N   1 
ATOM 1306 C CA  . LEU A 1 289 ? 131.131 121.811 103.357 1.00 96.05  ? 289 LEU A CA  1 
ATOM 1307 C C   . LEU A 1 289 ? 131.504 121.975 101.893 1.00 94.95  ? 289 LEU A C   1 
ATOM 1308 O O   . LEU A 1 289 ? 131.136 122.970 101.261 1.00 95.97  ? 289 LEU A O   1 
ATOM 1309 C CB  . LEU A 1 289 ? 132.303 122.196 104.257 1.00 98.17  ? 289 LEU A CB  1 
ATOM 1310 C CG  . LEU A 1 289 ? 131.948 122.824 105.605 1.00 102.09 ? 289 LEU A CG  1 
ATOM 1311 C CD1 . LEU A 1 289 ? 133.090 123.689 106.105 1.00 112.92 ? 289 LEU A CD1 1 
ATOM 1312 C CD2 . LEU A 1 289 ? 130.662 123.629 105.513 1.00 98.08  ? 289 LEU A CD2 1 
ATOM 1313 N N   . ARG A 1 290 ? 132.232 121.006 101.332 1.00 95.29  ? 290 ARG A N   1 
ATOM 1314 C CA  . ARG A 1 290 ? 132.579 121.086 99.916  1.00 92.50  ? 290 ARG A CA  1 
ATOM 1315 C C   . ARG A 1 290 ? 131.334 121.055 99.038  1.00 92.77  ? 290 ARG A C   1 
ATOM 1316 O O   . ARG A 1 290 ? 131.208 121.846 98.093  1.00 96.36  ? 290 ARG A O   1 
ATOM 1317 C CB  . ARG A 1 290 ? 133.526 119.948 99.539  1.00 96.92  ? 290 ARG A CB  1 
ATOM 1318 C CG  . ARG A 1 290 ? 133.263 119.358 98.164  1.00 94.14  ? 290 ARG A CG  1 
ATOM 1319 C CD  . ARG A 1 290 ? 134.548 119.035 97.435  1.00 99.04  ? 290 ARG A CD  1 
ATOM 1320 N NE  . ARG A 1 290 ? 135.413 120.200 97.309  1.00 104.45 ? 290 ARG A NE  1 
ATOM 1321 C CZ  . ARG A 1 290 ? 136.616 120.178 96.755  1.00 104.75 ? 290 ARG A CZ  1 
ATOM 1322 N NH1 . ARG A 1 290 ? 137.131 119.061 96.269  1.00 101.23 ? 290 ARG A NH1 1 
ATOM 1323 N NH2 . ARG A 1 290 ? 137.320 121.304 96.687  1.00 102.45 ? 290 ARG A NH2 1 
ATOM 1324 N N   . ILE A 1 291 ? 130.392 120.162 99.347  1.00 93.71  ? 291 ILE A N   1 
ATOM 1325 C CA  . ILE A 1 291 ? 129.186 120.052 98.532  1.00 89.63  ? 291 ILE A CA  1 
ATOM 1326 C C   . ILE A 1 291 ? 128.388 121.347 98.588  1.00 89.80  ? 291 ILE A C   1 
ATOM 1327 O O   . ILE A 1 291 ? 127.908 121.843 97.563  1.00 88.99  ? 291 ILE A O   1 
ATOM 1328 C CB  . ILE A 1 291 ? 128.345 118.845 98.985  1.00 89.38  ? 291 ILE A CB  1 
ATOM 1329 C CG1 . ILE A 1 291 ? 128.808 117.581 98.267  1.00 94.87  ? 291 ILE A CG1 1 
ATOM 1330 C CG2 . ILE A 1 291 ? 126.875 119.081 98.707  1.00 87.36  ? 291 ILE A CG2 1 
ATOM 1331 C CD1 . ILE A 1 291 ? 127.940 116.384 98.542  1.00 98.46  ? 291 ILE A CD1 1 
ATOM 1332 N N   . LEU A 1 292 ? 128.247 121.924 99.783  1.00 90.11  ? 292 LEU A N   1 
ATOM 1333 C CA  . LEU A 1 292 ? 127.487 123.161 99.920  1.00 86.89  ? 292 LEU A CA  1 
ATOM 1334 C C   . LEU A 1 292 ? 128.201 124.341 99.274  1.00 88.03  ? 292 LEU A C   1 
ATOM 1335 O O   . LEU A 1 292 ? 127.543 125.245 98.751  1.00 91.57  ? 292 LEU A O   1 
ATOM 1336 C CB  . LEU A 1 292 ? 127.212 123.447 101.393 1.00 87.33  ? 292 LEU A CB  1 
ATOM 1337 C CG  . LEU A 1 292 ? 126.238 122.493 102.083 1.00 89.97  ? 292 LEU A CG  1 
ATOM 1338 C CD1 . LEU A 1 292 ? 125.829 123.042 103.434 1.00 97.08  ? 292 LEU A CD1 1 
ATOM 1339 C CD2 . LEU A 1 292 ? 125.021 122.253 101.215 1.00 87.34  ? 292 LEU A CD2 1 
ATOM 1340 N N   . MET A 1 293 ? 129.532 124.358 99.298  1.00 85.90  ? 293 MET A N   1 
ATOM 1341 C CA  . MET A 1 293 ? 130.279 125.412 98.628  1.00 84.37  ? 293 MET A CA  1 
ATOM 1342 C C   . MET A 1 293 ? 130.372 125.193 97.128  1.00 87.45  ? 293 MET A C   1 
ATOM 1343 O O   . MET A 1 293 ? 130.913 126.055 96.428  1.00 92.75  ? 293 MET A O   1 
ATOM 1344 C CB  . MET A 1 293 ? 131.685 125.529 99.214  1.00 87.17  ? 293 MET A CB  1 
ATOM 1345 C CG  . MET A 1 293 ? 131.730 126.211 100.563 1.00 91.39  ? 293 MET A CG  1 
ATOM 1346 S SD  . MET A 1 293 ? 131.931 127.994 100.432 1.00 103.65 ? 293 MET A SD  1 
ATOM 1347 C CE  . MET A 1 293 ? 133.494 128.090 99.576  1.00 98.02  ? 293 MET A CE  1 
ATOM 1348 N N   . GLU A 1 294 ? 129.885 124.053 96.636  1.00 89.81  ? 294 GLU A N   1 
ATOM 1349 C CA  . GLU A 1 294 ? 129.747 123.792 95.202  1.00 90.62  ? 294 GLU A CA  1 
ATOM 1350 C C   . GLU A 1 294 ? 131.110 123.608 94.538  1.00 93.05  ? 294 GLU A C   1 
ATOM 1351 O O   . GLU A 1 294 ? 131.386 124.162 93.474  1.00 93.62  ? 294 GLU A O   1 
ATOM 1352 C CB  . GLU A 1 294 ? 128.947 124.899 94.513  1.00 86.44  ? 294 GLU A CB  1 
ATOM 1353 C CG  . GLU A 1 294 ? 127.459 124.785 94.715  1.00 91.25  ? 294 GLU A CG  1 
ATOM 1354 C CD  . GLU A 1 294 ? 126.697 124.862 93.420  1.00 93.60  ? 294 GLU A CD  1 
ATOM 1355 O OE1 . GLU A 1 294 ? 127.013 125.742 92.597  1.00 91.65  ? 294 GLU A OE1 1 
ATOM 1356 O OE2 . GLU A 1 294 ? 125.786 124.037 93.222  1.00 94.26  ? 294 GLU A OE2 1 
ATOM 1357 N N   . GLY A 1 295 ? 131.964 122.824 95.180  1.00 93.21  ? 295 GLY A N   1 
ATOM 1358 C CA  . GLY A 1 295 ? 133.213 122.431 94.571  1.00 94.36  ? 295 GLY A CA  1 
ATOM 1359 C C   . GLY A 1 295 ? 133.062 121.193 93.714  1.00 90.09  ? 295 GLY A C   1 
ATOM 1360 O O   . GLY A 1 295 ? 132.012 120.559 93.676  1.00 89.28  ? 295 GLY A O   1 
ATOM 1361 N N   . THR A 1 296 ? 134.141 120.854 93.022  1.00 88.31  ? 296 THR A N   1 
ATOM 1362 C CA  . THR A 1 296 ? 134.150 119.645 92.219  1.00 88.46  ? 296 THR A CA  1 
ATOM 1363 C C   . THR A 1 296 ? 133.995 118.427 93.126  1.00 96.32  ? 296 THR A C   1 
ATOM 1364 O O   . THR A 1 296 ? 134.605 118.373 94.199  1.00 104.64 ? 296 THR A O   1 
ATOM 1365 C CB  . THR A 1 296 ? 135.452 119.547 91.425  1.00 91.49  ? 296 THR A CB  1 
ATOM 1366 O OG1 . THR A 1 296 ? 135.849 120.855 91.002  1.00 91.38  ? 296 THR A OG1 1 
ATOM 1367 C CG2 . THR A 1 296 ? 135.272 118.669 90.205  1.00 95.18  ? 296 THR A CG2 1 
ATOM 1368 N N   . PRO A 1 297 ? 133.180 117.445 92.742  1.00 94.86  ? 297 PRO A N   1 
ATOM 1369 C CA  . PRO A 1 297 ? 133.051 116.236 93.561  1.00 101.43 ? 297 PRO A CA  1 
ATOM 1370 C C   . PRO A 1 297 ? 134.379 115.505 93.682  1.00 109.21 ? 297 PRO A C   1 
ATOM 1371 O O   . PRO A 1 297 ? 135.238 115.583 92.802  1.00 110.01 ? 297 PRO A O   1 
ATOM 1372 C CB  . PRO A 1 297 ? 132.016 115.400 92.799  1.00 100.49 ? 297 PRO A CB  1 
ATOM 1373 C CG  . PRO A 1 297 ? 131.987 115.979 91.421  1.00 94.41  ? 297 PRO A CG  1 
ATOM 1374 C CD  . PRO A 1 297 ? 132.253 117.432 91.602  1.00 89.46  ? 297 PRO A CD  1 
ATOM 1375 N N   . ARG A 1 298 ? 134.546 114.798 94.802  1.00 110.70 ? 298 ARG A N   1 
ATOM 1376 C CA  . ARG A 1 298 ? 135.817 114.132 95.074  1.00 113.27 ? 298 ARG A CA  1 
ATOM 1377 C C   . ARG A 1 298 ? 136.148 113.098 94.006  1.00 112.69 ? 298 ARG A C   1 
ATOM 1378 O O   . ARG A 1 298 ? 137.294 113.011 93.551  1.00 110.72 ? 298 ARG A O   1 
ATOM 1379 C CB  . ARG A 1 298 ? 135.781 113.474 96.452  1.00 119.13 ? 298 ARG A CB  1 
ATOM 1380 C CG  . ARG A 1 298 ? 136.410 114.302 97.554  1.00 121.65 ? 298 ARG A CG  1 
ATOM 1381 C CD  . ARG A 1 298 ? 135.532 115.483 97.937  1.00 121.41 ? 298 ARG A CD  1 
ATOM 1382 N NE  . ARG A 1 298 ? 136.262 116.537 98.636  1.00 123.59 ? 298 ARG A NE  1 
ATOM 1383 C CZ  . ARG A 1 298 ? 136.909 116.388 99.786  1.00 127.57 ? 298 ARG A CZ  1 
ATOM 1384 N NH1 . ARG A 1 298 ? 136.912 115.237 100.438 1.00 128.31 ? 298 ARG A NH1 1 
ATOM 1385 N NH2 . ARG A 1 298 ? 137.558 117.428 100.302 1.00 128.90 ? 298 ARG A NH2 1 
ATOM 1386 N N   . ASN A 1 299 ? 135.160 112.304 93.597  1.00 110.81 ? 299 ASN A N   1 
ATOM 1387 C CA  . ASN A 1 299 ? 135.417 111.250 92.622  1.00 110.29 ? 299 ASN A CA  1 
ATOM 1388 C C   . ASN A 1 299 ? 135.834 111.828 91.276  1.00 113.97 ? 299 ASN A C   1 
ATOM 1389 O O   . ASN A 1 299 ? 136.716 111.281 90.606  1.00 117.50 ? 299 ASN A O   1 
ATOM 1390 C CB  . ASN A 1 299 ? 134.177 110.373 92.461  1.00 114.12 ? 299 ASN A CB  1 
ATOM 1391 C CG  . ASN A 1 299 ? 133.351 110.295 93.727  1.00 123.21 ? 299 ASN A CG  1 
ATOM 1392 O OD1 . ASN A 1 299 ? 133.882 110.090 94.818  1.00 127.86 ? 299 ASN A OD1 1 
ATOM 1393 N ND2 . ASN A 1 299 ? 132.042 110.459 93.588  1.00 121.90 ? 299 ASN A ND2 1 
ATOM 1394 N N   . VAL A 1 300 ? 135.215 112.929 90.869  1.00 114.78 ? 300 VAL A N   1 
ATOM 1395 C CA  . VAL A 1 300 ? 135.395 113.479 89.532  1.00 112.52 ? 300 VAL A CA  1 
ATOM 1396 C C   . VAL A 1 300 ? 136.520 114.503 89.550  1.00 107.45 ? 300 VAL A C   1 
ATOM 1397 O O   . VAL A 1 300 ? 136.530 115.417 90.382  1.00 107.16 ? 300 VAL A O   1 
ATOM 1398 C CB  . VAL A 1 300 ? 134.090 114.108 89.022  1.00 107.32 ? 300 VAL A CB  1 
ATOM 1399 C CG1 . VAL A 1 300 ? 134.301 114.711 87.657  1.00 104.24 ? 300 VAL A CG1 1 
ATOM 1400 C CG2 . VAL A 1 300 ? 132.987 113.067 88.984  1.00 103.08 ? 300 VAL A CG2 1 
ATOM 1401 N N   . GLY A 1 301 ? 137.466 114.356 88.629  1.00 101.67 ? 301 GLY A N   1 
ATOM 1402 C CA  . GLY A 1 301 ? 138.568 115.292 88.494  1.00 102.23 ? 301 GLY A CA  1 
ATOM 1403 C C   . GLY A 1 301 ? 138.315 116.268 87.358  1.00 102.58 ? 301 GLY A C   1 
ATOM 1404 O O   . GLY A 1 301 ? 137.794 115.894 86.309  1.00 107.04 ? 301 GLY A O   1 
ATOM 1405 N N   . PHE A 1 302 ? 138.690 117.527 87.587  1.00 97.23  ? 302 PHE A N   1 
ATOM 1406 C CA  . PHE A 1 302 ? 138.500 118.557 86.571  1.00 92.98  ? 302 PHE A CA  1 
ATOM 1407 C C   . PHE A 1 302 ? 139.305 118.253 85.315  1.00 95.56  ? 302 PHE A C   1 
ATOM 1408 O O   . PHE A 1 302 ? 138.794 118.371 84.194  1.00 98.22  ? 302 PHE A O   1 
ATOM 1409 C CB  . PHE A 1 302 ? 138.892 119.917 87.148  1.00 90.84  ? 302 PHE A CB  1 
ATOM 1410 C CG  . PHE A 1 302 ? 138.656 121.070 86.219  1.00 91.31  ? 302 PHE A CG  1 
ATOM 1411 C CD1 . PHE A 1 302 ? 137.442 121.730 86.212  1.00 89.05  ? 302 PHE A CD1 1 
ATOM 1412 C CD2 . PHE A 1 302 ? 139.655 121.510 85.370  1.00 96.42  ? 302 PHE A CD2 1 
ATOM 1413 C CE1 . PHE A 1 302 ? 137.226 122.796 85.368  1.00 90.00  ? 302 PHE A CE1 1 
ATOM 1414 C CE2 . PHE A 1 302 ? 139.443 122.575 84.524  1.00 97.13  ? 302 PHE A CE2 1 
ATOM 1415 C CZ  . PHE A 1 302 ? 138.227 123.218 84.523  1.00 94.92  ? 302 PHE A CZ  1 
ATOM 1416 N N   . GLU A 1 303 ? 140.565 117.861 85.484  1.00 98.59  ? 303 GLU A N   1 
ATOM 1417 C CA  . GLU A 1 303 ? 141.427 117.610 84.331  1.00 103.49 ? 303 GLU A CA  1 
ATOM 1418 C C   . GLU A 1 303 ? 140.941 116.458 83.463  1.00 105.65 ? 303 GLU A C   1 
ATOM 1419 O O   . GLU A 1 303 ? 140.916 116.618 82.230  1.00 107.20 ? 303 GLU A O   1 
ATOM 1420 C CB  . GLU A 1 303 ? 142.865 117.383 84.805  1.00 109.72 ? 303 GLU A CB  1 
ATOM 1421 C CG  . GLU A 1 303 ? 143.740 118.607 84.704  1.00 113.98 ? 303 GLU A CG  1 
ATOM 1422 C CD  . GLU A 1 303 ? 143.534 119.358 83.410  1.00 117.89 ? 303 GLU A CD  1 
ATOM 1423 O OE1 . GLU A 1 303 ? 143.732 118.761 82.332  1.00 117.11 ? 303 GLU A OE1 1 
ATOM 1424 O OE2 . GLU A 1 303 ? 143.171 120.550 83.475  1.00 120.17 ? 303 GLU A OE2 1 
ATOM 1425 N N   . PRO A 1 304 ? 140.591 115.280 84.002  1.00 106.24 ? 304 PRO A N   1 
ATOM 1426 C CA  . PRO A 1 304 ? 140.078 114.220 83.119  1.00 103.39 ? 304 PRO A CA  1 
ATOM 1427 C C   . PRO A 1 304 ? 138.841 114.632 82.348  1.00 102.31 ? 304 PRO A C   1 
ATOM 1428 O O   . PRO A 1 304 ? 138.710 114.292 81.167  1.00 102.44 ? 304 PRO A O   1 
ATOM 1429 C CB  . PRO A 1 304 ? 139.783 113.070 84.090  1.00 103.19 ? 304 PRO A CB  1 
ATOM 1430 C CG  . PRO A 1 304 ? 140.677 113.312 85.237  1.00 106.72 ? 304 PRO A CG  1 
ATOM 1431 C CD  . PRO A 1 304 ? 140.739 114.797 85.386  1.00 104.74 ? 304 PRO A CD  1 
ATOM 1432 N N   . VAL A 1 305 ? 137.934 115.376 82.982  1.00 98.49  ? 305 VAL A N   1 
ATOM 1433 C CA  . VAL A 1 305 ? 136.734 115.831 82.290  1.00 91.93  ? 305 VAL A CA  1 
ATOM 1434 C C   . VAL A 1 305 ? 137.097 116.788 81.165  1.00 93.05  ? 305 VAL A C   1 
ATOM 1435 O O   . VAL A 1 305 ? 136.555 116.697 80.056  1.00 96.63  ? 305 VAL A O   1 
ATOM 1436 C CB  . VAL A 1 305 ? 135.752 116.472 83.284  1.00 86.41  ? 305 VAL A CB  1 
ATOM 1437 C CG1 . VAL A 1 305 ? 134.549 117.018 82.552  1.00 86.48  ? 305 VAL A CG1 1 
ATOM 1438 C CG2 . VAL A 1 305 ? 135.319 115.459 84.312  1.00 88.21  ? 305 VAL A CG2 1 
ATOM 1439 N N   . ARG A 1 306 ? 138.017 117.719 81.426  1.00 93.62  ? 306 ARG A N   1 
ATOM 1440 C CA  . ARG A 1 306 ? 138.418 118.653 80.380  1.00 93.61  ? 306 ARG A CA  1 
ATOM 1441 C C   . ARG A 1 306 ? 139.036 117.917 79.199  1.00 100.28 ? 306 ARG A C   1 
ATOM 1442 O O   . ARG A 1 306 ? 138.672 118.163 78.043  1.00 104.47 ? 306 ARG A O   1 
ATOM 1443 C CB  . ARG A 1 306 ? 139.388 119.692 80.936  1.00 98.76  ? 306 ARG A CB  1 
ATOM 1444 C CG  . ARG A 1 306 ? 139.124 121.092 80.417  1.00 100.60 ? 306 ARG A CG  1 
ATOM 1445 C CD  . ARG A 1 306 ? 140.403 121.896 80.275  1.00 109.15 ? 306 ARG A CD  1 
ATOM 1446 N NE  . ARG A 1 306 ? 141.470 121.117 79.660  1.00 116.16 ? 306 ARG A NE  1 
ATOM 1447 C CZ  . ARG A 1 306 ? 142.735 121.136 80.056  1.00 119.84 ? 306 ARG A CZ  1 
ATOM 1448 N NH1 . ARG A 1 306 ? 143.137 121.917 81.044  1.00 119.43 ? 306 ARG A NH1 1 
ATOM 1449 N NH2 . ARG A 1 306 ? 143.620 120.359 79.438  1.00 116.94 ? 306 ARG A NH2 1 
ATOM 1450 N N   . ASP A 1 307 ? 139.956 116.986 79.470  1.00 101.68 ? 307 ASP A N   1 
ATOM 1451 C CA  . ASP A 1 307 ? 140.577 116.248 78.373  1.00 101.42 ? 307 ASP A CA  1 
ATOM 1452 C C   . ASP A 1 307 ? 139.552 115.422 77.611  1.00 101.95 ? 307 ASP A C   1 
ATOM 1453 O O   . ASP A 1 307 ? 139.615 115.330 76.381  1.00 101.01 ? 307 ASP A O   1 
ATOM 1454 C CB  . ASP A 1 307 ? 141.715 115.357 78.873  1.00 107.01 ? 307 ASP A CB  1 
ATOM 1455 C CG  . ASP A 1 307 ? 142.530 116.004 79.968  1.00 118.40 ? 307 ASP A CG  1 
ATOM 1456 O OD1 . ASP A 1 307 ? 142.938 115.289 80.907  1.00 122.36 ? 307 ASP A OD1 1 
ATOM 1457 O OD2 . ASP A 1 307 ? 142.771 117.226 79.888  1.00 120.95 ? 307 ASP A OD2 1 
ATOM 1458 N N   . THR A 1 308 ? 138.592 114.821 78.318  1.00 100.61 ? 308 THR A N   1 
ATOM 1459 C CA  . THR A 1 308 ? 137.531 114.090 77.637  1.00 99.71  ? 308 THR A CA  1 
ATOM 1460 C C   . THR A 1 308 ? 136.747 115.007 76.711  1.00 100.42 ? 308 THR A C   1 
ATOM 1461 O O   . THR A 1 308 ? 136.411 114.627 75.583  1.00 102.62 ? 308 THR A O   1 
ATOM 1462 C CB  . THR A 1 308 ? 136.601 113.442 78.661  1.00 97.91  ? 308 THR A CB  1 
ATOM 1463 O OG1 . THR A 1 308 ? 137.298 112.394 79.345  1.00 103.99 ? 308 THR A OG1 1 
ATOM 1464 C CG2 . THR A 1 308 ? 135.372 112.866 77.982  1.00 97.73  ? 308 THR A CG2 1 
ATOM 1465 N N   . LEU A 1 309 ? 136.453 116.225 77.168  1.00 101.11 ? 309 LEU A N   1 
ATOM 1466 C CA  . LEU A 1 309 ? 135.717 117.167 76.332  1.00 94.54  ? 309 LEU A CA  1 
ATOM 1467 C C   . LEU A 1 309 ? 136.519 117.568 75.099  1.00 100.49 ? 309 LEU A C   1 
ATOM 1468 O O   . LEU A 1 309 ? 135.966 117.648 73.998  1.00 106.56 ? 309 LEU A O   1 
ATOM 1469 C CB  . LEU A 1 309 ? 135.329 118.398 77.145  1.00 86.71  ? 309 LEU A CB  1 
ATOM 1470 C CG  . LEU A 1 309 ? 134.155 118.187 78.098  1.00 82.27  ? 309 LEU A CG  1 
ATOM 1471 C CD1 . LEU A 1 309 ? 133.758 119.490 78.758  1.00 84.81  ? 309 LEU A CD1 1 
ATOM 1472 C CD2 . LEU A 1 309 ? 132.981 117.579 77.359  1.00 80.06  ? 309 LEU A CD2 1 
ATOM 1473 N N   . LEU A 1 310 ? 137.821 117.818 75.256  1.00 99.74  ? 310 LEU A N   1 
ATOM 1474 C CA  . LEU A 1 310 ? 138.613 118.268 74.115  1.00 101.31 ? 310 LEU A CA  1 
ATOM 1475 C C   . LEU A 1 310 ? 138.952 117.153 73.133  1.00 105.21 ? 310 LEU A C   1 
ATOM 1476 O O   . LEU A 1 310 ? 139.313 117.451 71.990  1.00 107.38 ? 310 LEU A O   1 
ATOM 1477 C CB  . LEU A 1 310 ? 139.909 118.941 74.574  1.00 100.83 ? 310 LEU A CB  1 
ATOM 1478 C CG  . LEU A 1 310 ? 139.812 120.296 75.274  1.00 99.15  ? 310 LEU A CG  1 
ATOM 1479 C CD1 . LEU A 1 310 ? 140.400 120.250 76.664  1.00 97.11  ? 310 LEU A CD1 1 
ATOM 1480 C CD2 . LEU A 1 310 ? 140.508 121.355 74.448  1.00 99.33  ? 310 LEU A CD2 1 
ATOM 1481 N N   . SER A 1 311 ? 138.851 115.887 73.536  1.00 104.02 ? 311 SER A N   1 
ATOM 1482 C CA  . SER A 1 311 ? 139.142 114.797 72.613  1.00 109.06 ? 311 SER A CA  1 
ATOM 1483 C C   . SER A 1 311 ? 137.993 114.491 71.664  1.00 115.61 ? 311 SER A C   1 
ATOM 1484 O O   . SER A 1 311 ? 138.168 113.676 70.752  1.00 114.12 ? 311 SER A O   1 
ATOM 1485 C CB  . SER A 1 311 ? 139.516 113.526 73.378  1.00 111.68 ? 311 SER A CB  1 
ATOM 1486 O OG  . SER A 1 311 ? 140.449 113.802 74.404  1.00 117.06 ? 311 SER A OG  1 
ATOM 1487 N N   . VAL A 1 312 ? 136.834 115.105 71.858  1.00 114.98 ? 312 VAL A N   1 
ATOM 1488 C CA  . VAL A 1 312 ? 135.715 114.905 70.930  1.00 110.56 ? 312 VAL A CA  1 
ATOM 1489 C C   . VAL A 1 312 ? 136.094 115.472 69.567  1.00 115.76 ? 312 VAL A C   1 
ATOM 1490 O O   . VAL A 1 312 ? 136.606 116.603 69.493  1.00 115.57 ? 312 VAL A O   1 
ATOM 1491 C CB  . VAL A 1 312 ? 134.452 115.572 71.472  1.00 104.98 ? 312 VAL A CB  1 
ATOM 1492 C CG1 . VAL A 1 312 ? 133.321 115.461 70.470  1.00 112.65 ? 312 VAL A CG1 1 
ATOM 1493 C CG2 . VAL A 1 312 ? 134.056 114.950 72.797  1.00 106.60 ? 312 VAL A CG2 1 
ATOM 1494 N N   . PRO A 1 313 ? 135.885 114.738 68.475  1.00 121.73 ? 313 PRO A N   1 
ATOM 1495 C CA  . PRO A 1 313 ? 136.281 115.247 67.153  1.00 123.37 ? 313 PRO A CA  1 
ATOM 1496 C C   . PRO A 1 313 ? 135.522 116.515 66.796  1.00 122.28 ? 313 PRO A C   1 
ATOM 1497 O O   . PRO A 1 313 ? 134.301 116.506 66.632  1.00 118.59 ? 313 PRO A O   1 
ATOM 1498 C CB  . PRO A 1 313 ? 135.928 114.091 66.210  1.00 123.86 ? 313 PRO A CB  1 
ATOM 1499 C CG  . PRO A 1 313 ? 135.867 112.885 67.083  1.00 124.66 ? 313 PRO A CG  1 
ATOM 1500 C CD  . PRO A 1 313 ? 135.365 113.364 68.406  1.00 120.94 ? 313 PRO A CD  1 
ATOM 1501 N N   . GLY A 1 314 ? 136.262 117.613 66.673  1.00 120.19 ? 314 GLY A N   1 
ATOM 1502 C CA  . GLY A 1 314 ? 135.671 118.889 66.328  1.00 116.00 ? 314 GLY A CA  1 
ATOM 1503 C C   . GLY A 1 314 ? 135.883 119.953 67.384  1.00 116.98 ? 314 GLY A C   1 
ATOM 1504 O O   . GLY A 1 314 ? 136.062 121.129 67.060  1.00 119.99 ? 314 GLY A O   1 
ATOM 1505 N N   . VAL A 1 315 ? 135.875 119.552 68.654  1.00 114.83 ? 315 VAL A N   1 
ATOM 1506 C CA  . VAL A 1 315 ? 136.005 120.510 69.743  1.00 111.19 ? 315 VAL A CA  1 
ATOM 1507 C C   . VAL A 1 315 ? 137.421 121.064 69.768  1.00 113.82 ? 315 VAL A C   1 
ATOM 1508 O O   . VAL A 1 315 ? 138.401 120.310 69.716  1.00 117.37 ? 315 VAL A O   1 
ATOM 1509 C CB  . VAL A 1 315 ? 135.643 119.853 71.082  1.00 105.40 ? 315 VAL A CB  1 
ATOM 1510 C CG1 . VAL A 1 315 ? 135.881 120.819 72.225  1.00 101.64 ? 315 VAL A CG1 1 
ATOM 1511 C CG2 . VAL A 1 315 ? 134.202 119.391 71.070  1.00 101.53 ? 315 VAL A CG2 1 
ATOM 1512 N N   . ARG A 1 316 ? 137.536 122.387 69.842  1.00 111.39 ? 316 ARG A N   1 
ATOM 1513 C CA  . ARG A 1 316 ? 138.824 123.055 69.978  1.00 111.72 ? 316 ARG A CA  1 
ATOM 1514 C C   . ARG A 1 316 ? 139.163 123.433 71.408  1.00 110.77 ? 316 ARG A C   1 
ATOM 1515 O O   . ARG A 1 316 ? 140.290 123.201 71.847  1.00 116.29 ? 316 ARG A O   1 
ATOM 1516 C CB  . ARG A 1 316 ? 138.868 124.319 69.116  1.00 115.41 ? 316 ARG A CB  1 
ATOM 1517 C CG  . ARG A 1 316 ? 138.489 124.118 67.666  1.00 119.63 ? 316 ARG A CG  1 
ATOM 1518 C CD  . ARG A 1 316 ? 139.540 123.298 66.943  1.00 122.83 ? 316 ARG A CD  1 
ATOM 1519 N NE  . ARG A 1 316 ? 140.786 124.037 66.774  1.00 135.24 ? 316 ARG A NE  1 
ATOM 1520 C CZ  . ARG A 1 316 ? 140.991 124.987 65.872  1.00 141.49 ? 316 ARG A CZ  1 
ATOM 1521 N NH1 . ARG A 1 316 ? 140.039 125.368 65.037  1.00 137.91 ? 316 ARG A NH1 1 
ATOM 1522 N NH2 . ARG A 1 316 ? 142.180 125.577 65.810  1.00 141.74 ? 316 ARG A NH2 1 
ATOM 1523 N N   . ALA A 1 317 ? 138.224 124.019 72.145  1.00 103.83 ? 317 ALA A N   1 
ATOM 1524 C CA  . ALA A 1 317 ? 138.501 124.454 73.505  1.00 103.72 ? 317 ALA A CA  1 
ATOM 1525 C C   . ALA A 1 317 ? 137.194 124.549 74.272  1.00 101.15 ? 317 ALA A C   1 
ATOM 1526 O O   . ALA A 1 317 ? 136.113 124.620 73.686  1.00 103.01 ? 317 ALA A O   1 
ATOM 1527 C CB  . ALA A 1 317 ? 139.235 125.797 73.524  1.00 102.76 ? 317 ALA A CB  1 
ATOM 1528 N N   . THR A 1 318 ? 137.311 124.547 75.596  1.00 98.46  ? 318 THR A N   1 
ATOM 1529 C CA  . THR A 1 318 ? 136.179 124.722 76.494  1.00 97.35  ? 318 THR A CA  1 
ATOM 1530 C C   . THR A 1 318 ? 136.396 125.990 77.305  1.00 100.13 ? 318 THR A C   1 
ATOM 1531 O O   . THR A 1 318 ? 137.503 126.234 77.795  1.00 108.94 ? 318 THR A O   1 
ATOM 1532 C CB  . THR A 1 318 ? 136.011 123.517 77.422  1.00 95.16  ? 318 THR A CB  1 
ATOM 1533 O OG1 . THR A 1 318 ? 136.949 123.605 78.500  1.00 101.46 ? 318 THR A OG1 1 
ATOM 1534 C CG2 . THR A 1 318 ? 136.250 122.228 76.661  1.00 90.39  ? 318 THR A CG2 1 
ATOM 1535 N N   . HIS A 1 319 ? 135.348 126.800 77.438  1.00 92.54  ? 319 HIS A N   1 
ATOM 1536 C CA  . HIS A 1 319 ? 135.489 128.095 78.096  1.00 97.42  ? 319 HIS A CA  1 
ATOM 1537 C C   . HIS A 1 319 ? 135.145 128.025 79.580  1.00 98.46  ? 319 HIS A C   1 
ATOM 1538 O O   . HIS A 1 319 ? 135.990 128.318 80.431  1.00 108.74 ? 319 HIS A O   1 
ATOM 1539 C CB  . HIS A 1 319 ? 134.619 129.138 77.391  1.00 98.97  ? 319 HIS A CB  1 
ATOM 1540 C CG  . HIS A 1 319 ? 134.855 129.221 75.917  1.00 107.01 ? 319 HIS A CG  1 
ATOM 1541 N ND1 . HIS A 1 319 ? 136.045 128.843 75.333  1.00 105.15 ? 319 HIS A ND1 1 
ATOM 1542 C CD2 . HIS A 1 319 ? 134.057 129.641 74.908  1.00 109.68 ? 319 HIS A CD2 1 
ATOM 1543 C CE1 . HIS A 1 319 ? 135.968 129.025 74.027  1.00 107.75 ? 319 HIS A CE1 1 
ATOM 1544 N NE2 . HIS A 1 319 ? 134.773 129.508 73.743  1.00 113.54 ? 319 HIS A NE2 1 
ATOM 1545 N N   . GLU A 1 320 ? 133.916 127.641 79.907  1.00 86.09  ? 320 GLU A N   1 
ATOM 1546 C CA  . GLU A 1 320 ? 133.440 127.639 81.287  1.00 84.16  ? 320 GLU A CA  1 
ATOM 1547 C C   . GLU A 1 320 ? 132.987 126.231 81.642  1.00 81.64  ? 320 GLU A C   1 
ATOM 1548 O O   . GLU A 1 320 ? 131.823 125.875 81.452  1.00 88.39  ? 320 GLU A O   1 
ATOM 1549 C CB  . GLU A 1 320 ? 132.320 128.644 81.480  1.00 90.38  ? 320 GLU A CB  1 
ATOM 1550 C CG  . GLU A 1 320 ? 132.428 129.866 80.594  1.00 99.86  ? 320 GLU A CG  1 
ATOM 1551 C CD  . GLU A 1 320 ? 131.996 131.133 81.301  1.00 115.56 ? 320 GLU A CD  1 
ATOM 1552 O OE1 . GLU A 1 320 ? 131.192 131.038 82.251  1.00 113.98 ? 320 GLU A OE1 1 
ATOM 1553 O OE2 . GLU A 1 320 ? 132.462 132.222 80.907  1.00 126.00 ? 320 GLU A OE2 1 
ATOM 1554 N N   . LEU A 1 321 ? 133.909 125.434 82.168  1.00 76.41  ? 321 LEU A N   1 
ATOM 1555 C CA  . LEU A 1 321 ? 133.609 124.078 82.607  1.00 68.50  ? 321 LEU A CA  1 
ATOM 1556 C C   . LEU A 1 321 ? 133.232 124.127 84.081  1.00 70.99  ? 321 LEU A C   1 
ATOM 1557 O O   . LEU A 1 321 ? 134.072 124.429 84.932  1.00 82.66  ? 321 LEU A O   1 
ATOM 1558 C CB  . LEU A 1 321 ? 134.805 123.162 82.365  1.00 68.83  ? 321 LEU A CB  1 
ATOM 1559 C CG  . LEU A 1 321 ? 134.676 121.704 82.797  1.00 70.82  ? 321 LEU A CG  1 
ATOM 1560 C CD1 . LEU A 1 321 ? 133.485 121.055 82.134  1.00 73.96  ? 321 LEU A CD1 1 
ATOM 1561 C CD2 . LEU A 1 321 ? 135.943 120.952 82.454  1.00 81.49  ? 321 LEU A CD2 1 
ATOM 1562 N N   . HIS A 1 322 ? 131.971 123.839 84.381  1.00 68.79  ? 322 HIS A N   1 
ATOM 1563 C CA  . HIS A 1 322 ? 131.452 123.860 85.742  1.00 70.52  ? 322 HIS A CA  1 
ATOM 1564 C C   . HIS A 1 322 ? 131.133 122.435 86.164  1.00 70.31  ? 322 HIS A C   1 
ATOM 1565 O O   . HIS A 1 322 ? 130.356 121.749 85.495  1.00 72.46  ? 322 HIS A O   1 
ATOM 1566 C CB  . HIS A 1 322 ? 130.200 124.727 85.841  1.00 73.87  ? 322 HIS A CB  1 
ATOM 1567 C CG  . HIS A 1 322 ? 130.459 126.189 85.668  1.00 79.70  ? 322 HIS A CG  1 
ATOM 1568 N ND1 . HIS A 1 322 ? 131.138 126.940 86.601  1.00 81.54  ? 322 HIS A ND1 1 
ATOM 1569 C CD2 . HIS A 1 322 ? 130.124 127.041 84.671  1.00 80.11  ? 322 HIS A CD2 1 
ATOM 1570 C CE1 . HIS A 1 322 ? 131.214 128.191 86.185  1.00 85.65  ? 322 HIS A CE1 1 
ATOM 1571 N NE2 . HIS A 1 322 ? 130.606 128.279 85.017  1.00 86.05  ? 322 HIS A NE2 1 
ATOM 1572 N N   . LEU A 1 323 ? 131.725 121.996 87.268  1.00 72.15  ? 323 LEU A N   1 
ATOM 1573 C CA  . LEU A 1 323 ? 131.442 120.686 87.835  1.00 70.44  ? 323 LEU A CA  1 
ATOM 1574 C C   . LEU A 1 323 ? 131.057 120.864 89.293  1.00 78.83  ? 323 LEU A C   1 
ATOM 1575 O O   . LEU A 1 323 ? 131.789 121.498 90.057  1.00 91.30  ? 323 LEU A O   1 
ATOM 1576 C CB  . LEU A 1 323 ? 132.646 119.751 87.715  1.00 68.09  ? 323 LEU A CB  1 
ATOM 1577 C CG  . LEU A 1 323 ? 133.356 119.739 86.363  1.00 69.78  ? 323 LEU A CG  1 
ATOM 1578 C CD1 . LEU A 1 323 ? 134.661 118.985 86.456  1.00 78.59  ? 323 LEU A CD1 1 
ATOM 1579 C CD2 . LEU A 1 323 ? 132.464 119.128 85.308  1.00 72.81  ? 323 LEU A CD2 1 
ATOM 1580 N N   . TRP A 1 324 ? 129.906 120.319 89.671  1.00 69.66  ? 324 TRP A N   1 
ATOM 1581 C CA  . TRP A 1 324 ? 129.451 120.405 91.049  1.00 73.77  ? 324 TRP A CA  1 
ATOM 1582 C C   . TRP A 1 324 ? 128.505 119.247 91.311  1.00 77.72  ? 324 TRP A C   1 
ATOM 1583 O O   . TRP A 1 324 ? 128.019 118.599 90.382  1.00 83.21  ? 324 TRP A O   1 
ATOM 1584 C CB  . TRP A 1 324 ? 128.783 121.752 91.341  1.00 76.25  ? 324 TRP A CB  1 
ATOM 1585 C CG  . TRP A 1 324 ? 127.417 121.924 90.761  1.00 73.76  ? 324 TRP A CG  1 
ATOM 1586 C CD1 . TRP A 1 324 ? 126.231 121.747 91.402  1.00 77.27  ? 324 TRP A CD1 1 
ATOM 1587 C CD2 . TRP A 1 324 ? 127.096 122.320 89.425  1.00 69.67  ? 324 TRP A CD2 1 
ATOM 1588 N NE1 . TRP A 1 324 ? 125.189 122.008 90.550  1.00 74.51  ? 324 TRP A NE1 1 
ATOM 1589 C CE2 . TRP A 1 324 ? 125.695 122.360 89.328  1.00 68.65  ? 324 TRP A CE2 1 
ATOM 1590 C CE3 . TRP A 1 324 ? 127.858 122.642 88.301  1.00 71.15  ? 324 TRP A CE3 1 
ATOM 1591 C CZ2 . TRP A 1 324 ? 125.041 122.707 88.155  1.00 70.59  ? 324 TRP A CZ2 1 
ATOM 1592 C CZ3 . TRP A 1 324 ? 127.207 122.986 87.139  1.00 71.11  ? 324 TRP A CZ3 1 
ATOM 1593 C CH2 . TRP A 1 324 ? 125.813 123.016 87.073  1.00 71.96  ? 324 TRP A CH2 1 
ATOM 1594 N N   . ALA A 1 325 ? 128.260 118.984 92.589  1.00 77.82  ? 325 ALA A N   1 
ATOM 1595 C CA  . ALA A 1 325 ? 127.481 117.832 93.013  1.00 81.30  ? 325 ALA A CA  1 
ATOM 1596 C C   . ALA A 1 325 ? 126.293 118.282 93.846  1.00 82.49  ? 325 ALA A C   1 
ATOM 1597 O O   . ALA A 1 325 ? 126.454 119.051 94.798  1.00 90.94  ? 325 ALA A O   1 
ATOM 1598 C CB  . ALA A 1 325 ? 128.342 116.856 93.816  1.00 88.69  ? 325 ALA A CB  1 
ATOM 1599 N N   . LEU A 1 326 ? 125.102 117.806 93.482  1.00 82.06  ? 326 LEU A N   1 
ATOM 1600 C CA  . LEU A 1 326 ? 123.938 118.014 94.334  1.00 86.11  ? 326 LEU A CA  1 
ATOM 1601 C C   . LEU A 1 326 ? 124.098 117.283 95.657  1.00 92.39  ? 326 LEU A C   1 
ATOM 1602 O O   . LEU A 1 326 ? 123.794 117.832 96.722  1.00 94.92  ? 326 LEU A O   1 
ATOM 1603 C CB  . LEU A 1 326 ? 122.674 117.544 93.620  1.00 88.88  ? 326 LEU A CB  1 
ATOM 1604 C CG  . LEU A 1 326 ? 122.042 118.509 92.624  1.00 88.14  ? 326 LEU A CG  1 
ATOM 1605 C CD1 . LEU A 1 326 ? 120.595 118.137 92.397  1.00 90.37  ? 326 LEU A CD1 1 
ATOM 1606 C CD2 . LEU A 1 326 ? 122.150 119.921 93.135  1.00 90.41  ? 326 LEU A CD2 1 
ATOM 1607 N N   . THR A 1 327 ? 124.576 116.046 95.609  1.00 95.92  ? 327 THR A N   1 
ATOM 1608 C CA  . THR A 1 327 ? 124.804 115.240 96.799  1.00 98.48  ? 327 THR A CA  1 
ATOM 1609 C C   . THR A 1 327 ? 125.985 114.321 96.498  1.00 100.93 ? 327 THR A C   1 
ATOM 1610 O O   . THR A 1 327 ? 126.723 114.542 95.533  1.00 102.51 ? 327 THR A O   1 
ATOM 1611 C CB  . THR A 1 327 ? 123.514 114.498 97.192  1.00 99.38  ? 327 THR A CB  1 
ATOM 1612 O OG1 . THR A 1 327 ? 123.723 113.756 98.400  1.00 107.42 ? 327 THR A OG1 1 
ATOM 1613 C CG2 . THR A 1 327 ? 123.091 113.547 96.091  1.00 96.92  ? 327 THR A CG2 1 
ATOM 1614 N N   . LEU A 1 328 ? 126.174 113.292 97.325  1.00 102.67 ? 328 LEU A N   1 
ATOM 1615 C CA  . LEU A 1 328 ? 127.321 112.407 97.153  1.00 105.37 ? 328 LEU A CA  1 
ATOM 1616 C C   . LEU A 1 328 ? 127.272 111.681 95.815  1.00 104.66 ? 328 LEU A C   1 
ATOM 1617 O O   . LEU A 1 328 ? 128.302 111.520 95.150  1.00 107.43 ? 328 LEU A O   1 
ATOM 1618 C CB  . LEU A 1 328 ? 127.386 111.403 98.303  1.00 109.42 ? 328 LEU A CB  1 
ATOM 1619 C CG  . LEU A 1 328 ? 128.287 111.771 99.482  1.00 112.07 ? 328 LEU A CG  1 
ATOM 1620 C CD1 . LEU A 1 328 ? 129.699 112.055 99.003  1.00 110.34 ? 328 LEU A CD1 1 
ATOM 1621 C CD2 . LEU A 1 328 ? 127.726 112.958 100.243 1.00 106.63 ? 328 LEU A CD2 1 
ATOM 1622 N N   . THR A 1 329 ? 126.088 111.235 95.401  1.00 99.50  ? 329 THR A N   1 
ATOM 1623 C CA  . THR A 1 329 ? 125.953 110.418 94.205  1.00 99.90  ? 329 THR A CA  1 
ATOM 1624 C C   . THR A 1 329 ? 125.396 111.174 93.006  1.00 101.99 ? 329 THR A C   1 
ATOM 1625 O O   . THR A 1 329 ? 125.327 110.600 91.915  1.00 102.61 ? 329 THR A O   1 
ATOM 1626 C CB  . THR A 1 329 ? 125.057 109.209 94.492  1.00 107.38 ? 329 THR A CB  1 
ATOM 1627 O OG1 . THR A 1 329 ? 123.688 109.565 94.268  1.00 111.19 ? 329 THR A OG1 1 
ATOM 1628 C CG2 . THR A 1 329 ? 125.224 108.760 95.932  1.00 110.14 ? 329 THR A CG2 1 
ATOM 1629 N N   . TYR A 1 330 ? 125.000 112.432 93.172  1.00 100.03 ? 330 TYR A N   1 
ATOM 1630 C CA  . TYR A 1 330 ? 124.424 113.226 92.093  1.00 93.12  ? 330 TYR A CA  1 
ATOM 1631 C C   . TYR A 1 330 ? 125.436 114.274 91.653  1.00 91.42  ? 330 TYR A C   1 
ATOM 1632 O O   . TYR A 1 330 ? 125.862 115.104 92.460  1.00 95.90  ? 330 TYR A O   1 
ATOM 1633 C CB  . TYR A 1 330 ? 123.124 113.890 92.541  1.00 91.31  ? 330 TYR A CB  1 
ATOM 1634 C CG  . TYR A 1 330 ? 122.157 114.180 91.420  1.00 93.90  ? 330 TYR A CG  1 
ATOM 1635 C CD1 . TYR A 1 330 ? 121.219 113.241 91.027  1.00 101.23 ? 330 TYR A CD1 1 
ATOM 1636 C CD2 . TYR A 1 330 ? 122.177 115.399 90.762  1.00 94.99  ? 330 TYR A CD2 1 
ATOM 1637 C CE1 . TYR A 1 330 ? 120.332 113.506 90.005  1.00 103.51 ? 330 TYR A CE1 1 
ATOM 1638 C CE2 . TYR A 1 330 ? 121.294 115.673 89.741  1.00 101.64 ? 330 TYR A CE2 1 
ATOM 1639 C CZ  . TYR A 1 330 ? 120.374 114.724 89.367  1.00 104.55 ? 330 TYR A CZ  1 
ATOM 1640 O OH  . TYR A 1 330 ? 119.493 114.994 88.347  1.00 108.45 ? 330 TYR A OH  1 
ATOM 1641 N N   . HIS A 1 331 ? 125.805 114.241 90.377  1.00 86.11  ? 331 HIS A N   1 
ATOM 1642 C CA  . HIS A 1 331 ? 126.781 115.161 89.816  1.00 82.88  ? 331 HIS A CA  1 
ATOM 1643 C C   . HIS A 1 331 ? 126.188 115.849 88.597  1.00 84.82  ? 331 HIS A C   1 
ATOM 1644 O O   . HIS A 1 331 ? 125.445 115.234 87.828  1.00 91.71  ? 331 HIS A O   1 
ATOM 1645 C CB  . HIS A 1 331 ? 128.067 114.437 89.422  1.00 83.96  ? 331 HIS A CB  1 
ATOM 1646 C CG  . HIS A 1 331 ? 128.747 113.744 90.559  1.00 90.79  ? 331 HIS A CG  1 
ATOM 1647 N ND1 . HIS A 1 331 ? 128.560 114.109 91.873  1.00 93.50  ? 331 HIS A ND1 1 
ATOM 1648 C CD2 . HIS A 1 331 ? 129.617 112.708 90.577  1.00 96.45  ? 331 HIS A CD2 1 
ATOM 1649 C CE1 . HIS A 1 331 ? 129.284 113.327 92.653  1.00 95.96  ? 331 HIS A CE1 1 
ATOM 1650 N NE2 . HIS A 1 331 ? 129.936 112.469 91.891  1.00 100.47 ? 331 HIS A NE2 1 
ATOM 1651 N N   . VAL A 1 332 ? 126.522 117.128 88.427  1.00 75.68  ? 332 VAL A N   1 
ATOM 1652 C CA  . VAL A 1 332 ? 126.060 117.930 87.304  1.00 71.26  ? 332 VAL A CA  1 
ATOM 1653 C C   . VAL A 1 332 ? 127.277 118.558 86.640  1.00 70.95  ? 332 VAL A C   1 
ATOM 1654 O O   . VAL A 1 332 ? 128.330 118.724 87.256  1.00 77.03  ? 332 VAL A O   1 
ATOM 1655 C CB  . VAL A 1 332 ? 125.057 119.020 87.741  1.00 73.84  ? 332 VAL A CB  1 
ATOM 1656 C CG1 . VAL A 1 332 ? 124.236 119.498 86.562  1.00 80.10  ? 332 VAL A CG1 1 
ATOM 1657 C CG2 . VAL A 1 332 ? 124.153 118.506 88.841  1.00 77.70  ? 332 VAL A CG2 1 
ATOM 1658 N N   . ALA A 1 333 ? 127.129 118.901 85.362  1.00 68.88  ? 333 ALA A N   1 
ATOM 1659 C CA  . ALA A 1 333 ? 128.228 119.487 84.611  1.00 69.90  ? 333 ALA A CA  1 
ATOM 1660 C C   . ALA A 1 333 ? 127.694 120.470 83.580  1.00 76.17  ? 333 ALA A C   1 
ATOM 1661 O O   . ALA A 1 333 ? 126.546 120.374 83.144  1.00 82.07  ? 333 ALA A O   1 
ATOM 1662 C CB  . ALA A 1 333 ? 129.068 118.414 83.917  1.00 71.78  ? 333 ALA A CB  1 
ATOM 1663 N N   . SER A 1 334 ? 128.549 121.415 83.195  1.00 71.36  ? 334 SER A N   1 
ATOM 1664 C CA  . SER A 1 334 ? 128.240 122.385 82.155  1.00 65.51  ? 334 SER A CA  1 
ATOM 1665 C C   . SER A 1 334 ? 129.531 122.749 81.443  1.00 68.57  ? 334 SER A C   1 
ATOM 1666 O O   . SER A 1 334 ? 130.624 122.600 81.991  1.00 82.19  ? 334 SER A O   1 
ATOM 1667 C CB  . SER A 1 334 ? 127.577 123.640 82.724  1.00 71.34  ? 334 SER A CB  1 
ATOM 1668 O OG  . SER A 1 334 ? 126.561 123.304 83.648  1.00 83.77  ? 334 SER A OG  1 
ATOM 1669 N N   . ALA A 1 335 ? 129.401 123.233 80.213  1.00 64.51  ? 335 ALA A N   1 
ATOM 1670 C CA  . ALA A 1 335 ? 130.574 123.555 79.415  1.00 68.80  ? 335 ALA A CA  1 
ATOM 1671 C C   . ALA A 1 335 ? 130.176 124.515 78.306  1.00 77.01  ? 335 ALA A C   1 
ATOM 1672 O O   . ALA A 1 335 ? 128.994 124.766 78.068  1.00 80.32  ? 335 ALA A O   1 
ATOM 1673 C CB  . ALA A 1 335 ? 131.219 122.294 78.841  1.00 69.60  ? 335 ALA A CB  1 
ATOM 1674 N N   . HIS A 1 336 ? 131.187 125.047 77.627  1.00 77.22  ? 336 HIS A N   1 
ATOM 1675 C CA  . HIS A 1 336 ? 131.028 126.022 76.555  1.00 79.51  ? 336 HIS A CA  1 
ATOM 1676 C C   . HIS A 1 336 ? 131.890 125.641 75.361  1.00 80.79  ? 336 HIS A C   1 
ATOM 1677 O O   . HIS A 1 336 ? 132.661 126.448 74.841  1.00 92.48  ? 336 HIS A O   1 
ATOM 1678 C CB  . HIS A 1 336 ? 131.382 127.424 77.032  1.00 90.36  ? 336 HIS A CB  1 
ATOM 1679 C CG  . HIS A 1 336 ? 130.266 128.124 77.739  1.00 88.60  ? 336 HIS A CG  1 
ATOM 1680 N ND1 . HIS A 1 336 ? 129.856 129.394 77.400  1.00 87.02  ? 336 HIS A ND1 1 
ATOM 1681 C CD2 . HIS A 1 336 ? 129.483 127.739 78.773  1.00 85.05  ? 336 HIS A CD2 1 
ATOM 1682 C CE1 . HIS A 1 336 ? 128.863 129.759 78.190  1.00 86.93  ? 336 HIS A CE1 1 
ATOM 1683 N NE2 . HIS A 1 336 ? 128.618 128.773 79.033  1.00 84.49  ? 336 HIS A NE2 1 
ATOM 1684 N N   . LEU A 1 337 ? 131.781 124.389 74.922  1.00 75.85  ? 337 LEU A N   1 
ATOM 1685 C CA  . LEU A 1 337 ? 132.641 123.883 73.860  1.00 88.32  ? 337 LEU A CA  1 
ATOM 1686 C C   . LEU A 1 337 ? 132.538 124.743 72.608  1.00 91.67  ? 337 LEU A C   1 
ATOM 1687 O O   . LEU A 1 337 ? 131.448 125.148 72.201  1.00 94.07  ? 337 LEU A O   1 
ATOM 1688 C CB  . LEU A 1 337 ? 132.267 122.441 73.522  1.00 87.09  ? 337 LEU A CB  1 
ATOM 1689 C CG  . LEU A 1 337 ? 131.711 121.589 74.658  1.00 82.97  ? 337 LEU A CG  1 
ATOM 1690 C CD1 . LEU A 1 337 ? 131.124 120.307 74.108  1.00 76.72  ? 337 LEU A CD1 1 
ATOM 1691 C CD2 . LEU A 1 337 ? 132.797 121.289 75.664  1.00 88.63  ? 337 LEU A CD2 1 
ATOM 1692 N N   . ALA A 1 338 ? 133.688 125.029 72.003  1.00 90.91  ? 338 ALA A N   1 
ATOM 1693 C CA  . ALA A 1 338 ? 133.772 125.802 70.766  1.00 95.06  ? 338 ALA A CA  1 
ATOM 1694 C C   . ALA A 1 338 ? 134.285 124.876 69.669  1.00 102.32 ? 338 ALA A C   1 
ATOM 1695 O O   . ALA A 1 338 ? 135.466 124.519 69.653  1.00 110.29 ? 338 ALA A O   1 
ATOM 1696 C CB  . ALA A 1 338 ? 134.679 127.015 70.938  1.00 101.63 ? 338 ALA A CB  1 
ATOM 1697 N N   . ILE A 1 339 ? 133.403 124.494 68.749  1.00 107.11 ? 339 ILE A N   1 
ATOM 1698 C CA  . ILE A 1 339 ? 133.741 123.518 67.719  1.00 114.48 ? 339 ILE A CA  1 
ATOM 1699 C C   . ILE A 1 339 ? 134.452 124.184 66.552  1.00 121.58 ? 339 ILE A C   1 
ATOM 1700 O O   . ILE A 1 339 ? 134.491 125.415 66.447  1.00 122.52 ? 339 ILE A O   1 
ATOM 1701 C CB  . ILE A 1 339 ? 132.490 122.779 67.218  1.00 112.48 ? 339 ILE A CB  1 
ATOM 1702 C CG1 . ILE A 1 339 ? 131.611 123.732 66.408  1.00 115.21 ? 339 ILE A CG1 1 
ATOM 1703 C CG2 . ILE A 1 339 ? 131.730 122.183 68.387  1.00 109.82 ? 339 ILE A CG2 1 
ATOM 1704 C CD1 . ILE A 1 339 ? 130.178 123.291 66.276  1.00 117.75 ? 339 ILE A CD1 1 
ATOM 1705 N N   . ASP A 1 340 ? 135.017 123.365 65.670  1.00 124.73 ? 340 ASP A N   1 
ATOM 1706 C CA  . ASP A 1 340 ? 135.589 123.804 64.407  1.00 131.68 ? 340 ASP A CA  1 
ATOM 1707 C C   . ASP A 1 340 ? 134.466 124.196 63.459  1.00 137.00 ? 340 ASP A C   1 
ATOM 1708 O O   . ASP A 1 340 ? 133.322 123.762 63.626  1.00 138.16 ? 340 ASP A O   1 
ATOM 1709 C CB  . ASP A 1 340 ? 136.438 122.698 63.775  1.00 133.66 ? 340 ASP A CB  1 
ATOM 1710 C CG  . ASP A 1 340 ? 137.656 123.234 63.057  1.00 139.27 ? 340 ASP A CG  1 
ATOM 1711 O OD1 . ASP A 1 340 ? 138.733 123.292 63.682  1.00 138.72 ? 340 ASP A OD1 1 
ATOM 1712 O OD2 . ASP A 1 340 ? 137.534 123.603 61.871  1.00 142.07 ? 340 ASP A OD2 1 
ATOM 1713 N N   . SER A 1 341 ? 134.796 125.016 62.463  1.00 140.12 ? 341 SER A N   1 
ATOM 1714 C CA  . SER A 1 341 ? 133.816 125.428 61.465  1.00 141.19 ? 341 SER A CA  1 
ATOM 1715 C C   . SER A 1 341 ? 133.276 124.227 60.698  1.00 142.03 ? 341 SER A C   1 
ATOM 1716 O O   . SER A 1 341 ? 132.066 124.116 60.476  1.00 141.86 ? 341 SER A O   1 
ATOM 1717 C CB  . SER A 1 341 ? 134.432 126.440 60.498  1.00 144.51 ? 341 SER A CB  1 
ATOM 1718 O OG  . SER A 1 341 ? 135.563 125.892 59.845  1.00 149.89 ? 341 SER A OG  1 
ATOM 1719 N N   . THR A 1 342 ? 134.166 123.324 60.289  1.00 144.15 ? 342 THR A N   1 
ATOM 1720 C CA  . THR A 1 342 ? 133.766 122.133 59.552  1.00 146.88 ? 342 THR A CA  1 
ATOM 1721 C C   . THR A 1 342 ? 133.389 121.003 60.501  1.00 145.14 ? 342 THR A C   1 
ATOM 1722 O O   . THR A 1 342 ? 134.074 119.976 60.562  1.00 142.29 ? 342 THR A O   1 
ATOM 1723 C CB  . THR A 1 342 ? 134.888 121.690 58.607  1.00 148.25 ? 342 THR A CB  1 
ATOM 1724 O OG1 . THR A 1 342 ? 136.059 121.361 59.367  1.00 151.21 ? 342 THR A OG1 1 
ATOM 1725 C CG2 . THR A 1 342 ? 135.225 122.803 57.626  1.00 145.26 ? 342 THR A CG2 1 
ATOM 1726 N N   . ALA A 1 343 ? 132.297 121.178 61.241  1.00 142.47 ? 343 ALA A N   1 
ATOM 1727 C CA  . ALA A 1 343 ? 131.842 120.166 62.181  1.00 138.35 ? 343 ALA A CA  1 
ATOM 1728 C C   . ALA A 1 343 ? 130.324 120.198 62.260  1.00 135.05 ? 343 ALA A C   1 
ATOM 1729 O O   . ALA A 1 343 ? 129.682 121.180 61.877  1.00 133.80 ? 343 ALA A O   1 
ATOM 1730 C CB  . ALA A 1 343 ? 132.452 120.372 63.573  1.00 135.12 ? 343 ALA A CB  1 
ATOM 1731 N N   . ASP A 1 344 ? 129.754 119.103 62.768  1.00 135.44 ? 344 ASP A N   1 
ATOM 1732 C CA  . ASP A 1 344 ? 128.310 118.978 62.893  1.00 132.97 ? 344 ASP A CA  1 
ATOM 1733 C C   . ASP A 1 344 ? 127.994 119.187 64.366  1.00 128.98 ? 344 ASP A C   1 
ATOM 1734 O O   . ASP A 1 344 ? 128.312 118.314 65.187  1.00 128.25 ? 344 ASP A O   1 
ATOM 1735 C CB  . ASP A 1 344 ? 127.846 117.595 62.402  1.00 134.72 ? 344 ASP A CB  1 
ATOM 1736 C CG  . ASP A 1 344 ? 126.456 117.166 62.917  1.00 136.53 ? 344 ASP A CG  1 
ATOM 1737 O OD1 . ASP A 1 344 ? 125.951 116.146 62.398  1.00 140.48 ? 344 ASP A OD1 1 
ATOM 1738 O OD2 . ASP A 1 344 ? 125.829 117.824 63.764  1.00 131.74 ? 344 ASP A OD2 1 
ATOM 1739 N N   . PRO A 1 345 ? 127.387 120.314 64.747  1.00 125.64 ? 345 PRO A N   1 
ATOM 1740 C CA  . PRO A 1 345 ? 127.181 120.587 66.181  1.00 123.00 ? 345 PRO A CA  1 
ATOM 1741 C C   . PRO A 1 345 ? 126.359 119.536 66.901  1.00 122.25 ? 345 PRO A C   1 
ATOM 1742 O O   . PRO A 1 345 ? 126.654 119.219 68.059  1.00 121.18 ? 345 PRO A O   1 
ATOM 1743 C CB  . PRO A 1 345 ? 126.478 121.951 66.171  1.00 122.02 ? 345 PRO A CB  1 
ATOM 1744 C CG  . PRO A 1 345 ? 126.824 122.554 64.847  1.00 122.75 ? 345 PRO A CG  1 
ATOM 1745 C CD  . PRO A 1 345 ? 126.911 121.414 63.894  1.00 123.97 ? 345 PRO A CD  1 
ATOM 1746 N N   . GLU A 1 346 ? 125.335 118.983 66.251  1.00 125.26 ? 346 GLU A N   1 
ATOM 1747 C CA  . GLU A 1 346 ? 124.496 117.985 66.907  1.00 128.07 ? 346 GLU A CA  1 
ATOM 1748 C C   . GLU A 1 346 ? 125.286 116.720 67.216  1.00 123.15 ? 346 GLU A C   1 
ATOM 1749 O O   . GLU A 1 346 ? 125.194 116.170 68.320  1.00 118.07 ? 346 GLU A O   1 
ATOM 1750 C CB  . GLU A 1 346 ? 123.283 117.665 66.034  1.00 132.23 ? 346 GLU A CB  1 
ATOM 1751 C CG  . GLU A 1 346 ? 122.042 118.469 66.381  1.00 135.37 ? 346 GLU A CG  1 
ATOM 1752 C CD  . GLU A 1 346 ? 122.010 119.816 65.688  1.00 138.17 ? 346 GLU A CD  1 
ATOM 1753 O OE1 . GLU A 1 346 ? 121.989 119.843 64.441  1.00 142.42 ? 346 GLU A OE1 1 
ATOM 1754 O OE2 . GLU A 1 346 ? 122.009 120.849 66.389  1.00 135.82 ? 346 GLU A OE2 1 
ATOM 1755 N N   . ALA A 1 347 ? 126.071 116.242 66.248  1.00 125.07 ? 347 ALA A N   1 
ATOM 1756 C CA  . ALA A 1 347 ? 126.873 115.044 66.470  1.00 121.89 ? 347 ALA A CA  1 
ATOM 1757 C C   . ALA A 1 347 ? 127.910 115.269 67.561  1.00 117.58 ? 347 ALA A C   1 
ATOM 1758 O O   . ALA A 1 347 ? 128.114 114.405 68.422  1.00 116.86 ? 347 ALA A O   1 
ATOM 1759 C CB  . ALA A 1 347 ? 127.549 114.614 65.169  1.00 118.29 ? 347 ALA A CB  1 
ATOM 1760 N N   . VAL A 1 348 ? 128.570 116.428 67.543  1.00 116.16 ? 348 VAL A N   1 
ATOM 1761 C CA  . VAL A 1 348 ? 129.572 116.739 68.559  1.00 109.88 ? 348 VAL A CA  1 
ATOM 1762 C C   . VAL A 1 348 ? 128.931 116.775 69.938  1.00 108.68 ? 348 VAL A C   1 
ATOM 1763 O O   . VAL A 1 348 ? 129.457 116.211 70.905  1.00 110.86 ? 348 VAL A O   1 
ATOM 1764 C CB  . VAL A 1 348 ? 130.271 118.069 68.229  1.00 107.39 ? 348 VAL A CB  1 
ATOM 1765 C CG1 . VAL A 1 348 ? 130.907 118.660 69.473  1.00 103.13 ? 348 VAL A CG1 1 
ATOM 1766 C CG2 . VAL A 1 348 ? 131.307 117.866 67.141  1.00 110.66 ? 348 VAL A CG2 1 
ATOM 1767 N N   . LEU A 1 349 ? 127.778 117.436 70.046  1.00 107.96 ? 349 LEU A N   1 
ATOM 1768 C CA  . LEU A 1 349 ? 127.100 117.542 71.331  1.00 107.31 ? 349 LEU A CA  1 
ATOM 1769 C C   . LEU A 1 349 ? 126.677 116.172 71.842  1.00 110.55 ? 349 LEU A C   1 
ATOM 1770 O O   . LEU A 1 349 ? 126.871 115.850 73.021  1.00 111.06 ? 349 LEU A O   1 
ATOM 1771 C CB  . LEU A 1 349 ? 125.894 118.470 71.201  1.00 106.86 ? 349 LEU A CB  1 
ATOM 1772 C CG  . LEU A 1 349 ? 124.906 118.464 72.362  1.00 105.73 ? 349 LEU A CG  1 
ATOM 1773 C CD1 . LEU A 1 349 ? 125.562 119.008 73.617  1.00 97.02  ? 349 LEU A CD1 1 
ATOM 1774 C CD2 . LEU A 1 349 ? 123.678 119.273 71.998  1.00 103.65 ? 349 LEU A CD2 1 
ATOM 1775 N N   . ALA A 1 350 ? 126.104 115.346 70.963  1.00 113.21 ? 350 ALA A N   1 
ATOM 1776 C CA  . ALA A 1 350 ? 125.670 114.016 71.376  1.00 112.20 ? 350 ALA A CA  1 
ATOM 1777 C C   . ALA A 1 350 ? 126.850 113.164 71.818  1.00 112.84 ? 350 ALA A C   1 
ATOM 1778 O O   . ALA A 1 350 ? 126.776 112.466 72.837  1.00 113.01 ? 350 ALA A O   1 
ATOM 1779 C CB  . ALA A 1 350 ? 124.912 113.334 70.238  1.00 109.17 ? 350 ALA A CB  1 
ATOM 1780 N N   . GLU A 1 351 ? 127.954 113.216 71.068  1.00 111.33 ? 351 GLU A N   1 
ATOM 1781 C CA  . GLU A 1 351 ? 129.123 112.421 71.419  1.00 109.56 ? 351 GLU A CA  1 
ATOM 1782 C C   . GLU A 1 351 ? 129.710 112.869 72.751  1.00 108.28 ? 351 GLU A C   1 
ATOM 1783 O O   . GLU A 1 351 ? 130.088 112.036 73.583  1.00 110.37 ? 351 GLU A O   1 
ATOM 1784 C CB  . GLU A 1 351 ? 130.163 112.516 70.303  1.00 108.94 ? 351 GLU A CB  1 
ATOM 1785 C CG  . GLU A 1 351 ? 131.578 112.200 70.727  1.00 115.86 ? 351 GLU A CG  1 
ATOM 1786 C CD  . GLU A 1 351 ? 131.852 110.710 70.741  1.00 123.83 ? 351 GLU A CD  1 
ATOM 1787 O OE1 . GLU A 1 351 ? 130.924 109.931 70.441  1.00 127.95 ? 351 GLU A OE1 1 
ATOM 1788 O OE2 . GLU A 1 351 ? 132.998 110.316 71.037  1.00 123.56 ? 351 GLU A OE2 1 
ATOM 1789 N N   . ALA A 1 352 ? 129.777 114.183 72.981  1.00 105.76 ? 352 ALA A N   1 
ATOM 1790 C CA  . ALA A 1 352 ? 130.304 114.682 74.246  1.00 101.03 ? 352 ALA A CA  1 
ATOM 1791 C C   . ALA A 1 352 ? 129.416 114.281 75.416  1.00 103.30 ? 352 ALA A C   1 
ATOM 1792 O O   . ALA A 1 352 ? 129.916 113.886 76.477  1.00 106.02 ? 352 ALA A O   1 
ATOM 1793 C CB  . ALA A 1 352 ? 130.463 116.199 74.185  1.00 94.60  ? 352 ALA A CB  1 
ATOM 1794 N N   . SER A 1 353 ? 128.094 114.376 75.248  1.00 103.56 ? 353 SER A N   1 
ATOM 1795 C CA  . SER A 1 353 ? 127.200 113.985 76.334  1.00 103.52 ? 353 SER A CA  1 
ATOM 1796 C C   . SER A 1 353 ? 127.318 112.497 76.631  1.00 107.08 ? 353 SER A C   1 
ATOM 1797 O O   . SER A 1 353 ? 127.330 112.089 77.800  1.00 110.87 ? 353 SER A O   1 
ATOM 1798 C CB  . SER A 1 353 ? 125.754 114.347 75.998  1.00 109.33 ? 353 SER A CB  1 
ATOM 1799 O OG  . SER A 1 353 ? 125.493 114.204 74.617  1.00 112.56 ? 353 SER A OG  1 
ATOM 1800 N N   . SER A 1 354 ? 127.406 111.667 75.587  1.00 106.47 ? 354 SER A N   1 
ATOM 1801 C CA  . SER A 1 354 ? 127.555 110.234 75.811  1.00 108.18 ? 354 SER A CA  1 
ATOM 1802 C C   . SER A 1 354 ? 128.871 109.926 76.510  1.00 108.48 ? 354 SER A C   1 
ATOM 1803 O O   . SER A 1 354 ? 128.920 109.073 77.402  1.00 108.95 ? 354 SER A O   1 
ATOM 1804 C CB  . SER A 1 354 ? 127.460 109.468 74.493  1.00 107.21 ? 354 SER A CB  1 
ATOM 1805 O OG  . SER A 1 354 ? 128.091 110.167 73.441  1.00 106.85 ? 354 SER A OG  1 
ATOM 1806 N N   . ARG A 1 355 ? 129.950 110.610 76.119  1.00 106.82 ? 355 ARG A N   1 
ATOM 1807 C CA  . ARG A 1 355 ? 131.229 110.407 76.790  1.00 103.53 ? 355 ARG A CA  1 
ATOM 1808 C C   . ARG A 1 355 ? 131.138 110.769 78.264  1.00 104.37 ? 355 ARG A C   1 
ATOM 1809 O O   . ARG A 1 355 ? 131.602 110.016 79.127  1.00 111.94 ? 355 ARG A O   1 
ATOM 1810 C CB  . ARG A 1 355 ? 132.322 111.228 76.110  1.00 99.94  ? 355 ARG A CB  1 
ATOM 1811 C CG  . ARG A 1 355 ? 132.815 110.647 74.807  1.00 105.99 ? 355 ARG A CG  1 
ATOM 1812 C CD  . ARG A 1 355 ? 134.170 111.220 74.450  1.00 109.24 ? 355 ARG A CD  1 
ATOM 1813 N NE  . ARG A 1 355 ? 134.700 110.631 73.229  1.00 114.98 ? 355 ARG A NE  1 
ATOM 1814 C CZ  . ARG A 1 355 ? 135.840 110.991 72.657  1.00 115.20 ? 355 ARG A CZ  1 
ATOM 1815 N NH1 . ARG A 1 355 ? 136.605 111.935 73.178  1.00 114.60 ? 355 ARG A NH1 1 
ATOM 1816 N NH2 . ARG A 1 355 ? 136.220 110.389 71.534  1.00 114.21 ? 355 ARG A NH2 1 
ATOM 1817 N N   . LEU A 1 356 ? 130.541 111.920 78.575  1.00 101.20 ? 356 LEU A N   1 
ATOM 1818 C CA  . LEU A 1 356 ? 130.422 112.317 79.975  1.00 102.24 ? 356 LEU A CA  1 
ATOM 1819 C C   . LEU A 1 356 ? 129.614 111.295 80.761  1.00 103.44 ? 356 LEU A C   1 
ATOM 1820 O O   . LEU A 1 356 ? 130.027 110.859 81.843  1.00 102.83 ? 356 LEU A O   1 
ATOM 1821 C CB  . LEU A 1 356 ? 129.791 113.704 80.090  1.00 99.06  ? 356 LEU A CB  1 
ATOM 1822 C CG  . LEU A 1 356 ? 130.578 114.892 79.540  1.00 99.50  ? 356 LEU A CG  1 
ATOM 1823 C CD1 . LEU A 1 356 ? 129.889 116.189 79.909  1.00 92.74  ? 356 LEU A CD1 1 
ATOM 1824 C CD2 . LEU A 1 356 ? 131.998 114.881 80.066  1.00 97.72  ? 356 LEU A CD2 1 
ATOM 1825 N N   . TYR A 1 357 ? 128.472 110.873 80.214  1.00 105.27 ? 357 TYR A N   1 
ATOM 1826 C CA  . TYR A 1 357 ? 127.618 109.932 80.931  1.00 108.32 ? 357 TYR A CA  1 
ATOM 1827 C C   . TYR A 1 357 ? 128.320 108.597 81.145  1.00 109.94 ? 357 TYR A C   1 
ATOM 1828 O O   . TYR A 1 357 ? 128.251 108.021 82.237  1.00 113.20 ? 357 TYR A O   1 
ATOM 1829 C CB  . TYR A 1 357 ? 126.307 109.730 80.175  1.00 114.67 ? 357 TYR A CB  1 
ATOM 1830 C CG  . TYR A 1 357 ? 125.340 108.797 80.865  1.00 121.35 ? 357 TYR A CG  1 
ATOM 1831 C CD1 . TYR A 1 357 ? 124.494 107.978 80.132  1.00 123.94 ? 357 TYR A CD1 1 
ATOM 1832 C CD2 . TYR A 1 357 ? 125.257 108.751 82.250  1.00 119.37 ? 357 TYR A CD2 1 
ATOM 1833 C CE1 . TYR A 1 357 ? 123.606 107.128 80.759  1.00 127.65 ? 357 TYR A CE1 1 
ATOM 1834 C CE2 . TYR A 1 357 ? 124.374 107.905 82.885  1.00 124.89 ? 357 TYR A CE2 1 
ATOM 1835 C CZ  . TYR A 1 357 ? 123.550 107.097 82.135  1.00 133.02 ? 357 TYR A CZ  1 
ATOM 1836 O OH  . TYR A 1 357 ? 122.665 106.253 82.763  1.00 142.24 ? 357 TYR A OH  1 
ATOM 1837 N N   . SER A 1 358 ? 129.008 108.092 80.121  1.00 107.80 ? 358 SER A N   1 
ATOM 1838 C CA  . SER A 1 358 ? 129.606 106.766 80.222  1.00 106.88 ? 358 SER A CA  1 
ATOM 1839 C C   . SER A 1 358 ? 130.832 106.775 81.126  1.00 104.82 ? 358 SER A C   1 
ATOM 1840 O O   . SER A 1 358 ? 131.004 105.876 81.957  1.00 107.00 ? 358 SER A O   1 
ATOM 1841 C CB  . SER A 1 358 ? 129.957 106.242 78.830  1.00 106.45 ? 358 SER A CB  1 
ATOM 1842 O OG  . SER A 1 358 ? 131.309 106.504 78.503  1.00 104.68 ? 358 SER A OG  1 
ATOM 1843 N N   . ARG A 1 359 ? 131.696 107.784 80.992  1.00 101.95 ? 359 ARG A N   1 
ATOM 1844 C CA  . ARG A 1 359 ? 132.944 107.775 81.746  1.00 100.60 ? 359 ARG A CA  1 
ATOM 1845 C C   . ARG A 1 359 ? 132.746 108.249 83.179  1.00 102.25 ? 359 ARG A C   1 
ATOM 1846 O O   . ARG A 1 359 ? 133.231 107.611 84.119  1.00 103.30 ? 359 ARG A O   1 
ATOM 1847 C CB  . ARG A 1 359 ? 133.993 108.638 81.045  1.00 99.95  ? 359 ARG A CB  1 
ATOM 1848 C CG  . ARG A 1 359 ? 134.757 107.927 79.943  1.00 102.72 ? 359 ARG A CG  1 
ATOM 1849 C CD  . ARG A 1 359 ? 134.063 108.068 78.599  1.00 105.03 ? 359 ARG A CD  1 
ATOM 1850 N NE  . ARG A 1 359 ? 134.908 107.747 77.451  1.00 109.79 ? 359 ARG A NE  1 
ATOM 1851 C CZ  . ARG A 1 359 ? 136.108 108.261 77.202  1.00 110.52 ? 359 ARG A CZ  1 
ATOM 1852 N NH1 . ARG A 1 359 ? 136.638 109.201 77.967  1.00 105.96 ? 359 ARG A NH1 1 
ATOM 1853 N NH2 . ARG A 1 359 ? 136.783 107.837 76.138  1.00 111.55 ? 359 ARG A NH2 1 
ATOM 1854 N N   . PHE A 1 360 ? 132.045 109.366 83.373  1.00 98.05  ? 360 PHE A N   1 
ATOM 1855 C CA  . PHE A 1 360 ? 131.987 109.998 84.680  1.00 95.21  ? 360 PHE A CA  1 
ATOM 1856 C C   . PHE A 1 360 ? 130.630 109.892 85.356  1.00 94.96  ? 360 PHE A C   1 
ATOM 1857 O O   . PHE A 1 360 ? 130.507 110.291 86.519  1.00 92.97  ? 360 PHE A O   1 
ATOM 1858 C CB  . PHE A 1 360 ? 132.389 111.473 84.562  1.00 93.41  ? 360 PHE A CB  1 
ATOM 1859 C CG  . PHE A 1 360 ? 133.725 111.677 83.916  1.00 92.01  ? 360 PHE A CG  1 
ATOM 1860 C CD1 . PHE A 1 360 ? 134.882 111.650 84.671  1.00 96.83  ? 360 PHE A CD1 1 
ATOM 1861 C CD2 . PHE A 1 360 ? 133.827 111.876 82.553  1.00 92.10  ? 360 PHE A CD2 1 
ATOM 1862 C CE1 . PHE A 1 360 ? 136.112 111.830 84.080  1.00 99.10  ? 360 PHE A CE1 1 
ATOM 1863 C CE2 . PHE A 1 360 ? 135.055 112.053 81.956  1.00 95.89  ? 360 PHE A CE2 1 
ATOM 1864 C CZ  . PHE A 1 360 ? 136.199 112.031 82.721  1.00 99.31  ? 360 PHE A CZ  1 
ATOM 1865 N N   . GLY A 1 361 ? 129.619 109.366 84.674  1.00 99.91  ? 361 GLY A N   1 
ATOM 1866 C CA  . GLY A 1 361 ? 128.325 109.172 85.307  1.00 104.96 ? 361 GLY A CA  1 
ATOM 1867 C C   . GLY A 1 361 ? 127.664 110.455 85.756  1.00 101.41 ? 361 GLY A C   1 
ATOM 1868 O O   . GLY A 1 361 ? 127.116 110.515 86.864  1.00 101.24 ? 361 GLY A O   1 
ATOM 1869 N N   . PHE A 1 362 ? 127.717 111.492 84.928  1.00 101.11 ? 362 PHE A N   1 
ATOM 1870 C CA  . PHE A 1 362 ? 127.071 112.751 85.258  1.00 92.64  ? 362 PHE A CA  1 
ATOM 1871 C C   . PHE A 1 362 ? 125.568 112.624 85.059  1.00 95.09  ? 362 PHE A C   1 
ATOM 1872 O O   . PHE A 1 362 ? 125.109 112.184 84.001  1.00 103.13 ? 362 PHE A O   1 
ATOM 1873 C CB  . PHE A 1 362 ? 127.630 113.876 84.392  1.00 85.09  ? 362 PHE A CB  1 
ATOM 1874 C CG  . PHE A 1 362 ? 128.942 114.407 84.873  1.00 82.62  ? 362 PHE A CG  1 
ATOM 1875 C CD1 . PHE A 1 362 ? 129.059 114.950 86.136  1.00 77.84  ? 362 PHE A CD1 1 
ATOM 1876 C CD2 . PHE A 1 362 ? 130.060 114.362 84.065  1.00 89.07  ? 362 PHE A CD2 1 
ATOM 1877 C CE1 . PHE A 1 362 ? 130.264 115.437 86.585  1.00 74.33  ? 362 PHE A CE1 1 
ATOM 1878 C CE2 . PHE A 1 362 ? 131.267 114.849 84.509  1.00 85.12  ? 362 PHE A CE2 1 
ATOM 1879 C CZ  . PHE A 1 362 ? 131.368 115.387 85.771  1.00 74.34  ? 362 PHE A CZ  1 
ATOM 1880 N N   . SER A 1 363 ? 124.803 113.001 86.083  1.00 86.38  ? 363 SER A N   1 
ATOM 1881 C CA  . SER A 1 363 ? 123.351 112.939 85.976  1.00 89.93  ? 363 SER A CA  1 
ATOM 1882 C C   . SER A 1 363 ? 122.831 113.909 84.922  1.00 94.77  ? 363 SER A C   1 
ATOM 1883 O O   . SER A 1 363 ? 121.933 113.566 84.146  1.00 103.14 ? 363 SER A O   1 
ATOM 1884 C CB  . SER A 1 363 ? 122.714 113.227 87.332  1.00 93.45  ? 363 SER A CB  1 
ATOM 1885 O OG  . SER A 1 363 ? 123.226 112.356 88.324  1.00 100.92 ? 363 SER A OG  1 
ATOM 1886 N N   . SER A 1 364 ? 123.384 115.118 84.874  1.00 89.02  ? 364 SER A N   1 
ATOM 1887 C CA  . SER A 1 364 ? 122.974 116.126 83.912  1.00 87.75  ? 364 SER A CA  1 
ATOM 1888 C C   . SER A 1 364 ? 124.201 116.712 83.234  1.00 86.85  ? 364 SER A C   1 
ATOM 1889 O O   . SER A 1 364 ? 125.277 116.796 83.829  1.00 88.13  ? 364 SER A O   1 
ATOM 1890 C CB  . SER A 1 364 ? 122.167 117.244 84.576  1.00 88.64  ? 364 SER A CB  1 
ATOM 1891 O OG  . SER A 1 364 ? 121.063 116.718 85.289  1.00 104.27 ? 364 SER A OG  1 
ATOM 1892 N N   . CYS A 1 365 ? 124.029 117.117 81.979  1.00 87.18  ? 365 CYS A N   1 
ATOM 1893 C CA  . CYS A 1 365 ? 125.127 117.689 81.207  1.00 82.56  ? 365 CYS A CA  1 
ATOM 1894 C C   . CYS A 1 365 ? 124.538 118.671 80.207  1.00 85.20  ? 365 CYS A C   1 
ATOM 1895 O O   . CYS A 1 365 ? 123.912 118.256 79.228  1.00 86.83  ? 365 CYS A O   1 
ATOM 1896 C CB  . CYS A 1 365 ? 125.928 116.601 80.500  1.00 84.12  ? 365 CYS A CB  1 
ATOM 1897 S SG  . CYS A 1 365 ? 124.927 115.297 79.759  1.00 105.14 ? 365 CYS A SG  1 
ATOM 1898 N N   . THR A 1 366 ? 124.738 119.962 80.453  1.00 78.18  ? 366 THR A N   1 
ATOM 1899 C CA  . THR A 1 366 ? 124.308 121.024 79.551  1.00 72.96  ? 366 THR A CA  1 
ATOM 1900 C C   . THR A 1 366 ? 125.549 121.624 78.905  1.00 72.41  ? 366 THR A C   1 
ATOM 1901 O O   . THR A 1 366 ? 126.305 122.345 79.560  1.00 81.41  ? 366 THR A O   1 
ATOM 1902 C CB  . THR A 1 366 ? 123.516 122.092 80.298  1.00 73.74  ? 366 THR A CB  1 
ATOM 1903 O OG1 . THR A 1 366 ? 122.441 121.477 81.016  1.00 84.09  ? 366 THR A OG1 1 
ATOM 1904 C CG2 . THR A 1 366 ? 122.951 123.101 79.325  1.00 74.78  ? 366 THR A CG2 1 
ATOM 1905 N N   . LEU A 1 367 ? 125.755 121.335 77.626  1.00 69.70  ? 367 LEU A N   1 
ATOM 1906 C CA  . LEU A 1 367 ? 126.946 121.769 76.904  1.00 69.31  ? 367 LEU A CA  1 
ATOM 1907 C C   . LEU A 1 367 ? 126.542 122.780 75.840  1.00 70.54  ? 367 LEU A C   1 
ATOM 1908 O O   . LEU A 1 367 ? 125.870 122.427 74.867  1.00 81.90  ? 367 LEU A O   1 
ATOM 1909 C CB  . LEU A 1 367 ? 127.661 120.577 76.275  1.00 72.97  ? 367 LEU A CB  1 
ATOM 1910 C CG  . LEU A 1 367 ? 127.796 119.332 77.148  1.00 76.92  ? 367 LEU A CG  1 
ATOM 1911 C CD1 . LEU A 1 367 ? 128.323 118.184 76.325  1.00 91.44  ? 367 LEU A CD1 1 
ATOM 1912 C CD2 . LEU A 1 367 ? 128.709 119.599 78.323  1.00 74.21  ? 367 LEU A CD2 1 
ATOM 1913 N N   . GLN A 1 368 ? 126.963 124.027 76.017  1.00 65.22  ? 368 GLN A N   1 
ATOM 1914 C CA  . GLN A 1 368 ? 126.700 125.064 75.029  1.00 71.77  ? 368 GLN A CA  1 
ATOM 1915 C C   . GLN A 1 368 ? 127.733 124.968 73.917  1.00 84.19  ? 368 GLN A C   1 
ATOM 1916 O O   . GLN A 1 368 ? 128.935 125.092 74.167  1.00 91.74  ? 368 GLN A O   1 
ATOM 1917 C CB  . GLN A 1 368 ? 126.734 126.442 75.681  1.00 74.56  ? 368 GLN A CB  1 
ATOM 1918 C CG  . GLN A 1 368 ? 126.295 127.565 74.768  1.00 74.77  ? 368 GLN A CG  1 
ATOM 1919 C CD  . GLN A 1 368 ? 126.601 128.930 75.341  1.00 83.71  ? 368 GLN A CD  1 
ATOM 1920 O OE1 . GLN A 1 368 ? 126.233 129.237 76.473  1.00 85.99  ? 368 GLN A OE1 1 
ATOM 1921 N NE2 . GLN A 1 368 ? 127.276 129.761 74.560  1.00 95.38  ? 368 GLN A NE2 1 
ATOM 1922 N N   . VAL A 1 369 ? 127.271 124.753 72.692  1.00 85.68  ? 369 VAL A N   1 
ATOM 1923 C CA  . VAL A 1 369 ? 128.149 124.543 71.547  1.00 88.83  ? 369 VAL A CA  1 
ATOM 1924 C C   . VAL A 1 369 ? 128.222 125.845 70.763  1.00 94.82  ? 369 VAL A C   1 
ATOM 1925 O O   . VAL A 1 369 ? 127.287 126.203 70.039  1.00 104.68 ? 369 VAL A O   1 
ATOM 1926 C CB  . VAL A 1 369 ? 127.660 123.386 70.669  1.00 92.48  ? 369 VAL A CB  1 
ATOM 1927 C CG1 . VAL A 1 369 ? 128.468 123.319 69.398  1.00 94.79  ? 369 VAL A CG1 1 
ATOM 1928 C CG2 . VAL A 1 369 ? 127.759 122.078 71.425  1.00 91.57  ? 369 VAL A CG2 1 
ATOM 1929 N N   . GLU A 1 370 ? 129.335 126.559 70.909  1.00 95.70  ? 370 GLU A N   1 
ATOM 1930 C CA  . GLU A 1 370 ? 129.561 127.802 70.185  1.00 100.94 ? 370 GLU A CA  1 
ATOM 1931 C C   . GLU A 1 370 ? 130.302 127.527 68.885  1.00 108.37 ? 370 GLU A C   1 
ATOM 1932 O O   . GLU A 1 370 ? 130.417 126.373 68.462  1.00 110.07 ? 370 GLU A O   1 
ATOM 1933 C CB  . GLU A 1 370 ? 130.352 128.787 71.045  1.00 101.67 ? 370 GLU A CB  1 
ATOM 1934 C CG  . GLU A 1 370 ? 129.713 129.099 72.383  1.00 102.31 ? 370 GLU A CG  1 
ATOM 1935 C CD  . GLU A 1 370 ? 130.666 129.799 73.326  1.00 103.91 ? 370 GLU A CD  1 
ATOM 1936 O OE1 . GLU A 1 370 ? 131.829 130.017 72.934  1.00 106.98 ? 370 GLU A OE1 1 
ATOM 1937 O OE2 . GLU A 1 370 ? 130.257 130.128 74.459  1.00 96.66  ? 370 GLU A OE2 1 
ATOM 1938 N N   . GLN A 1 371 ? 130.798 128.579 68.241  1.00 116.39 ? 371 GLN A N   1 
ATOM 1939 C CA  . GLN A 1 371 ? 131.606 128.430 67.041  1.00 121.95 ? 371 GLN A CA  1 
ATOM 1940 C C   . GLN A 1 371 ? 132.907 129.192 67.237  1.00 127.21 ? 371 GLN A C   1 
ATOM 1941 O O   . GLN A 1 371 ? 132.923 130.302 67.775  1.00 130.51 ? 371 GLN A O   1 
ATOM 1942 C CB  . GLN A 1 371 ? 130.865 128.930 65.798  1.00 121.91 ? 371 GLN A CB  1 
ATOM 1943 C CG  . GLN A 1 371 ? 131.594 128.671 64.495  1.00 122.80 ? 371 GLN A CG  1 
ATOM 1944 C CD  . GLN A 1 371 ? 131.026 127.485 63.744  1.00 131.62 ? 371 GLN A CD  1 
ATOM 1945 O OE1 . GLN A 1 371 ? 130.324 126.652 64.317  1.00 130.94 ? 371 GLN A OE1 1 
ATOM 1946 N NE2 . GLN A 1 371 ? 131.323 127.405 62.453  1.00 137.66 ? 371 GLN A NE2 1 
ATOM 1947 N N   . TYR A 1 372 ? 134.002 128.579 66.802  1.00 127.65 ? 372 TYR A N   1 
ATOM 1948 C CA  . TYR A 1 372 ? 135.324 129.166 66.987  1.00 131.71 ? 372 TYR A CA  1 
ATOM 1949 C C   . TYR A 1 372 ? 135.485 130.438 66.162  1.00 131.67 ? 372 TYR A C   1 
ATOM 1950 O O   . TYR A 1 372 ? 136.111 131.401 66.604  1.00 126.24 ? 372 TYR A O   1 
ATOM 1951 C CB  . TYR A 1 372 ? 136.418 128.164 66.615  1.00 128.76 ? 372 TYR A CB  1 
ATOM 1952 C CG  . TYR A 1 372 ? 137.703 128.356 67.387  1.00 131.12 ? 372 TYR A CG  1 
ATOM 1953 C CD1 . TYR A 1 372 ? 138.798 127.534 67.165  1.00 132.61 ? 372 TYR A CD1 1 
ATOM 1954 C CD2 . TYR A 1 372 ? 137.816 129.348 68.350  1.00 130.18 ? 372 TYR A CD2 1 
ATOM 1955 C CE1 . TYR A 1 372 ? 139.972 127.702 67.871  1.00 134.75 ? 372 TYR A CE1 1 
ATOM 1956 C CE2 . TYR A 1 372 ? 138.985 129.525 69.062  1.00 134.14 ? 372 TYR A CE2 1 
ATOM 1957 C CZ  . TYR A 1 372 ? 140.061 128.699 68.818  1.00 136.75 ? 372 TYR A CZ  1 
ATOM 1958 O OH  . TYR A 1 372 ? 141.228 128.870 69.525  1.00 139.14 ? 372 TYR A OH  1 
ATOM 1959 N N   . ALA B 1 78  ? 132.180 148.968 107.326 1.00 169.67 ? 78  ALA B N   1 
ATOM 1960 C CA  . ALA B 1 78  ? 132.985 150.182 107.284 1.00 172.75 ? 78  ALA B CA  1 
ATOM 1961 C C   . ALA B 1 78  ? 134.009 150.193 108.413 1.00 173.72 ? 78  ALA B C   1 
ATOM 1962 O O   . ALA B 1 78  ? 134.993 149.456 108.379 1.00 170.25 ? 78  ALA B O   1 
ATOM 1963 C CB  . ALA B 1 78  ? 132.094 151.413 107.362 1.00 168.35 ? 78  ALA B CB  1 
ATOM 1964 N N   . ALA B 1 79  ? 133.770 151.034 109.413 1.00 174.21 ? 79  ALA B N   1 
ATOM 1965 C CA  . ALA B 1 79  ? 134.649 151.169 110.566 1.00 172.55 ? 79  ALA B CA  1 
ATOM 1966 C C   . ALA B 1 79  ? 133.917 150.814 111.854 1.00 172.81 ? 79  ALA B C   1 
ATOM 1967 O O   . ALA B 1 79  ? 134.079 151.470 112.885 1.00 170.23 ? 79  ALA B O   1 
ATOM 1968 C CB  . ALA B 1 79  ? 135.229 152.579 110.646 1.00 170.49 ? 79  ALA B CB  1 
ATOM 1969 N N   . CYS B 1 80  ? 133.100 149.766 111.809 1.00 174.03 ? 80  CYS B N   1 
ATOM 1970 C CA  . CYS B 1 80  ? 132.351 149.315 112.981 1.00 168.80 ? 80  CYS B CA  1 
ATOM 1971 C C   . CYS B 1 80  ? 133.185 148.381 113.852 1.00 168.41 ? 80  CYS B C   1 
ATOM 1972 O O   . CYS B 1 80  ? 132.757 147.289 114.220 1.00 166.44 ? 80  CYS B O   1 
ATOM 1973 C CB  . CYS B 1 80  ? 131.058 148.639 112.544 1.00 163.12 ? 80  CYS B CB  1 
ATOM 1974 S SG  . CYS B 1 80  ? 129.818 149.760 111.874 1.00 160.48 ? 80  CYS B SG  1 
ATOM 1975 N N   . ALA B 1 81  ? 134.396 148.817 114.190 1.00 171.18 ? 81  ALA B N   1 
ATOM 1976 C CA  . ALA B 1 81  ? 135.250 148.052 115.086 1.00 171.91 ? 81  ALA B CA  1 
ATOM 1977 C C   . ALA B 1 81  ? 134.940 148.326 116.548 1.00 171.83 ? 81  ALA B C   1 
ATOM 1978 O O   . ALA B 1 81  ? 135.203 147.472 117.403 1.00 173.10 ? 81  ALA B O   1 
ATOM 1979 C CB  . ALA B 1 81  ? 136.723 148.358 114.806 1.00 171.98 ? 81  ALA B CB  1 
ATOM 1980 N N   . VAL B 1 82  ? 134.377 149.499 116.852 1.00 172.31 ? 82  VAL B N   1 
ATOM 1981 C CA  . VAL B 1 82  ? 134.004 149.829 118.222 1.00 172.60 ? 82  VAL B CA  1 
ATOM 1982 C C   . VAL B 1 82  ? 132.839 148.993 118.723 1.00 170.49 ? 82  VAL B C   1 
ATOM 1983 O O   . VAL B 1 82  ? 132.562 148.988 119.927 1.00 168.31 ? 82  VAL B O   1 
ATOM 1984 C CB  . VAL B 1 82  ? 133.668 151.329 118.338 1.00 173.56 ? 82  VAL B CB  1 
ATOM 1985 C CG1 . VAL B 1 82  ? 132.213 151.579 117.984 1.00 171.10 ? 82  VAL B CG1 1 
ATOM 1986 C CG2 . VAL B 1 82  ? 133.987 151.843 119.733 1.00 171.91 ? 82  VAL B CG2 1 
ATOM 1987 N N   . CYS B 1 83  ? 132.145 148.286 117.831 1.00 170.65 ? 83  CYS B N   1 
ATOM 1988 C CA  . CYS B 1 83  ? 131.059 147.420 118.269 1.00 165.76 ? 83  CYS B CA  1 
ATOM 1989 C C   . CYS B 1 83  ? 131.588 146.170 118.958 1.00 164.85 ? 83  CYS B C   1 
ATOM 1990 O O   . CYS B 1 83  ? 130.893 145.585 119.795 1.00 159.96 ? 83  CYS B O   1 
ATOM 1991 C CB  . CYS B 1 83  ? 130.181 147.045 117.078 1.00 157.80 ? 83  CYS B CB  1 
ATOM 1992 S SG  . CYS B 1 83  ? 129.917 148.408 115.926 1.00 156.33 ? 83  CYS B SG  1 
ATOM 1993 N N   . PHE B 1 84  ? 132.808 145.749 118.623 1.00 168.62 ? 84  PHE B N   1 
ATOM 1994 C CA  . PHE B 1 84  ? 133.377 144.566 119.259 1.00 170.07 ? 84  PHE B CA  1 
ATOM 1995 C C   . PHE B 1 84  ? 133.819 144.860 120.686 1.00 170.33 ? 84  PHE B C   1 
ATOM 1996 O O   . PHE B 1 84  ? 133.617 144.035 121.584 1.00 171.03 ? 84  PHE B O   1 
ATOM 1997 C CB  . PHE B 1 84  ? 134.547 144.035 118.433 1.00 175.43 ? 84  PHE B CB  1 
ATOM 1998 C CG  . PHE B 1 84  ? 134.612 142.537 118.378 1.00 180.67 ? 84  PHE B CG  1 
ATOM 1999 C CD1 . PHE B 1 84  ? 134.826 141.798 119.529 1.00 182.08 ? 84  PHE B CD1 1 
ATOM 2000 C CD2 . PHE B 1 84  ? 134.456 141.868 117.176 1.00 182.00 ? 84  PHE B CD2 1 
ATOM 2001 C CE1 . PHE B 1 84  ? 134.885 140.420 119.483 1.00 185.66 ? 84  PHE B CE1 1 
ATOM 2002 C CE2 . PHE B 1 84  ? 134.514 140.489 117.124 1.00 184.29 ? 84  PHE B CE2 1 
ATOM 2003 C CZ  . PHE B 1 84  ? 134.729 139.764 118.278 1.00 186.47 ? 84  PHE B CZ  1 
ATOM 2004 N N   . VAL B 1 85  ? 134.441 146.017 120.917 1.00 170.58 ? 85  VAL B N   1 
ATOM 2005 C CA  . VAL B 1 85  ? 134.784 146.394 122.285 1.00 169.46 ? 85  VAL B CA  1 
ATOM 2006 C C   . VAL B 1 85  ? 133.519 146.702 123.075 1.00 167.24 ? 85  VAL B C   1 
ATOM 2007 O O   . VAL B 1 85  ? 133.418 146.379 124.265 1.00 165.58 ? 85  VAL B O   1 
ATOM 2008 C CB  . VAL B 1 85  ? 135.774 147.574 122.295 1.00 170.08 ? 85  VAL B CB  1 
ATOM 2009 C CG1 . VAL B 1 85  ? 135.321 148.668 121.355 1.00 171.30 ? 85  VAL B CG1 1 
ATOM 2010 C CG2 . VAL B 1 85  ? 135.953 148.117 123.706 1.00 169.54 ? 85  VAL B CG2 1 
ATOM 2011 N N   . PHE B 1 86  ? 132.529 147.318 122.425 1.00 167.08 ? 86  PHE B N   1 
ATOM 2012 C CA  . PHE B 1 86  ? 131.253 147.554 123.089 1.00 163.85 ? 86  PHE B CA  1 
ATOM 2013 C C   . PHE B 1 86  ? 130.546 146.246 123.411 1.00 159.49 ? 86  PHE B C   1 
ATOM 2014 O O   . PHE B 1 86  ? 129.735 146.193 124.339 1.00 154.84 ? 86  PHE B O   1 
ATOM 2015 C CB  . PHE B 1 86  ? 130.365 148.446 122.225 1.00 160.99 ? 86  PHE B CB  1 
ATOM 2016 C CG  . PHE B 1 86  ? 130.286 149.863 122.710 1.00 163.54 ? 86  PHE B CG  1 
ATOM 2017 C CD1 . PHE B 1 86  ? 131.405 150.490 123.231 1.00 168.50 ? 86  PHE B CD1 1 
ATOM 2018 C CD2 . PHE B 1 86  ? 129.100 150.568 122.646 1.00 157.94 ? 86  PHE B CD2 1 
ATOM 2019 C CE1 . PHE B 1 86  ? 131.341 151.794 123.679 1.00 169.07 ? 86  PHE B CE1 1 
ATOM 2020 C CE2 . PHE B 1 86  ? 129.028 151.872 123.091 1.00 159.42 ? 86  PHE B CE2 1 
ATOM 2021 C CZ  . PHE B 1 86  ? 130.150 152.486 123.609 1.00 168.35 ? 86  PHE B CZ  1 
ATOM 2022 N N   . MET B 1 87  ? 130.840 145.185 122.657 1.00 161.00 ? 87  MET B N   1 
ATOM 2023 C CA  . MET B 1 87  ? 130.355 143.857 123.017 1.00 154.85 ? 87  MET B CA  1 
ATOM 2024 C C   . MET B 1 87  ? 130.884 143.420 124.374 1.00 154.36 ? 87  MET B C   1 
ATOM 2025 O O   . MET B 1 87  ? 130.156 142.811 125.165 1.00 152.57 ? 87  MET B O   1 
ATOM 2026 C CB  . MET B 1 87  ? 130.759 142.841 121.954 1.00 152.75 ? 87  MET B CB  1 
ATOM 2027 C CG  . MET B 1 87  ? 130.101 141.495 122.124 1.00 143.94 ? 87  MET B CG  1 
ATOM 2028 S SD  . MET B 1 87  ? 128.684 141.210 121.066 1.00 144.38 ? 87  MET B SD  1 
ATOM 2029 C CE  . MET B 1 87  ? 128.682 139.425 121.084 1.00 135.10 ? 87  MET B CE  1 
ATOM 2030 N N   . ALA B 1 88  ? 132.157 143.707 124.652 1.00 157.08 ? 88  ALA B N   1 
ATOM 2031 C CA  . ALA B 1 88  ? 132.768 143.247 125.893 1.00 155.31 ? 88  ALA B CA  1 
ATOM 2032 C C   . ALA B 1 88  ? 132.030 143.770 127.116 1.00 155.12 ? 88  ALA B C   1 
ATOM 2033 O O   . ALA B 1 88  ? 131.976 143.086 128.142 1.00 155.23 ? 88  ALA B O   1 
ATOM 2034 C CB  . ALA B 1 88  ? 134.236 143.665 125.942 1.00 159.60 ? 88  ALA B CB  1 
ATOM 2035 N N   . GLY B 1 89  ? 131.442 144.964 127.020 1.00 155.66 ? 89  GLY B N   1 
ATOM 2036 C CA  . GLY B 1 89  ? 130.748 145.531 128.166 1.00 153.55 ? 89  GLY B CA  1 
ATOM 2037 C C   . GLY B 1 89  ? 129.597 144.669 128.646 1.00 150.88 ? 89  GLY B C   1 
ATOM 2038 O O   . GLY B 1 89  ? 129.375 144.529 129.851 1.00 150.24 ? 89  GLY B O   1 
ATOM 2039 N N   . GLU B 1 90  ? 128.847 144.081 127.713 1.00 150.72 ? 90  GLU B N   1 
ATOM 2040 C CA  . GLU B 1 90  ? 127.747 143.205 128.099 1.00 148.40 ? 90  GLU B CA  1 
ATOM 2041 C C   . GLU B 1 90  ? 128.248 141.912 128.724 1.00 152.76 ? 90  GLU B C   1 
ATOM 2042 O O   . GLU B 1 90  ? 127.628 141.401 129.662 1.00 155.34 ? 90  GLU B O   1 
ATOM 2043 C CB  . GLU B 1 90  ? 126.844 142.881 126.902 1.00 139.85 ? 90  GLU B CB  1 
ATOM 2044 C CG  . GLU B 1 90  ? 125.856 143.968 126.435 1.00 140.84 ? 90  GLU B CG  1 
ATOM 2045 C CD  . GLU B 1 90  ? 126.471 145.241 125.878 1.00 147.81 ? 90  GLU B CD  1 
ATOM 2046 O OE1 . GLU B 1 90  ? 127.702 145.372 125.819 1.00 154.94 ? 90  GLU B OE1 1 
ATOM 2047 O OE2 . GLU B 1 90  ? 125.695 146.131 125.481 1.00 144.47 ? 90  GLU B OE2 1 
ATOM 2048 N N   . VAL B 1 91  ? 129.355 141.365 128.222 1.00 153.58 ? 91  VAL B N   1 
ATOM 2049 C CA  . VAL B 1 91  ? 129.832 140.082 128.726 1.00 158.62 ? 91  VAL B CA  1 
ATOM 2050 C C   . VAL B 1 91  ? 130.298 140.212 130.171 1.00 160.57 ? 91  VAL B C   1 
ATOM 2051 O O   . VAL B 1 91  ? 129.923 139.409 131.033 1.00 160.62 ? 91  VAL B O   1 
ATOM 2052 C CB  . VAL B 1 91  ? 130.944 139.528 127.819 1.00 163.25 ? 91  VAL B CB  1 
ATOM 2053 C CG1 . VAL B 1 91  ? 131.064 138.025 127.997 1.00 168.09 ? 91  VAL B CG1 1 
ATOM 2054 C CG2 . VAL B 1 91  ? 130.657 139.870 126.369 1.00 157.54 ? 91  VAL B CG2 1 
ATOM 2055 N N   . VAL B 1 92  ? 131.115 141.224 130.463 1.00 159.67 ? 92  VAL B N   1 
ATOM 2056 C CA  . VAL B 1 92  ? 131.618 141.376 131.824 1.00 160.38 ? 92  VAL B CA  1 
ATOM 2057 C C   . VAL B 1 92  ? 130.573 142.040 132.712 1.00 157.47 ? 92  VAL B C   1 
ATOM 2058 O O   . VAL B 1 92  ? 130.321 141.592 133.835 1.00 156.41 ? 92  VAL B O   1 
ATOM 2059 C CB  . VAL B 1 92  ? 132.951 142.150 131.835 1.00 163.99 ? 92  VAL B CB  1 
ATOM 2060 C CG1 . VAL B 1 92  ? 132.843 143.451 131.059 1.00 159.79 ? 92  VAL B CG1 1 
ATOM 2061 C CG2 . VAL B 1 92  ? 133.399 142.412 133.264 1.00 164.07 ? 92  VAL B CG2 1 
ATOM 2062 N N   . GLY B 1 93  ? 129.939 143.106 132.217 1.00 154.93 ? 93  GLY B N   1 
ATOM 2063 C CA  . GLY B 1 93  ? 128.946 143.801 133.020 1.00 153.32 ? 93  GLY B CA  1 
ATOM 2064 C C   . GLY B 1 93  ? 127.770 142.917 133.380 1.00 152.74 ? 93  GLY B C   1 
ATOM 2065 O O   . GLY B 1 93  ? 127.261 142.968 134.503 1.00 152.86 ? 93  GLY B O   1 
ATOM 2066 N N   . GLY B 1 94  ? 127.318 142.097 132.431 1.00 149.73 ? 94  GLY B N   1 
ATOM 2067 C CA  . GLY B 1 94  ? 126.285 141.128 132.738 1.00 146.11 ? 94  GLY B CA  1 
ATOM 2068 C C   . GLY B 1 94  ? 126.738 140.073 133.726 1.00 151.22 ? 94  GLY B C   1 
ATOM 2069 O O   . GLY B 1 94  ? 125.931 139.568 134.510 1.00 150.63 ? 94  GLY B O   1 
ATOM 2070 N N   . TYR B 1 95  ? 128.024 139.716 133.697 1.00 152.61 ? 95  TYR B N   1 
ATOM 2071 C CA  . TYR B 1 95  ? 128.544 138.760 134.669 1.00 153.22 ? 95  TYR B CA  1 
ATOM 2072 C C   . TYR B 1 95  ? 128.432 139.319 136.082 1.00 152.04 ? 95  TYR B C   1 
ATOM 2073 O O   . TYR B 1 95  ? 127.931 138.647 136.990 1.00 152.80 ? 95  TYR B O   1 
ATOM 2074 C CB  . TYR B 1 95  ? 129.996 138.414 134.333 1.00 154.32 ? 95  TYR B CB  1 
ATOM 2075 C CG  . TYR B 1 95  ? 130.659 137.411 135.260 1.00 158.65 ? 95  TYR B CG  1 
ATOM 2076 C CD1 . TYR B 1 95  ? 132.041 137.284 135.292 1.00 160.04 ? 95  TYR B CD1 1 
ATOM 2077 C CD2 . TYR B 1 95  ? 129.907 136.555 136.058 1.00 160.00 ? 95  TYR B CD2 1 
ATOM 2078 C CE1 . TYR B 1 95  ? 132.656 136.368 136.125 1.00 162.94 ? 95  TYR B CE1 1 
ATOM 2079 C CE2 . TYR B 1 95  ? 130.513 135.637 136.891 1.00 160.71 ? 95  TYR B CE2 1 
ATOM 2080 C CZ  . TYR B 1 95  ? 131.888 135.546 136.919 1.00 163.28 ? 95  TYR B CZ  1 
ATOM 2081 O OH  . TYR B 1 95  ? 132.497 134.629 137.745 1.00 162.13 ? 95  TYR B OH  1 
ATOM 2082 N N   . LEU B 1 96  ? 128.884 140.559 136.282 1.00 150.54 ? 96  LEU B N   1 
ATOM 2083 C CA  . LEU B 1 96  ? 128.787 141.171 137.603 1.00 150.96 ? 96  LEU B CA  1 
ATOM 2084 C C   . LEU B 1 96  ? 127.335 141.327 138.030 1.00 150.83 ? 96  LEU B C   1 
ATOM 2085 O O   . LEU B 1 96  ? 126.983 141.038 139.179 1.00 153.88 ? 96  LEU B O   1 
ATOM 2086 C CB  . LEU B 1 96  ? 129.492 142.528 137.619 1.00 148.31 ? 96  LEU B CB  1 
ATOM 2087 C CG  . LEU B 1 96  ? 130.681 142.761 136.687 1.00 148.07 ? 96  LEU B CG  1 
ATOM 2088 C CD1 . LEU B 1 96  ? 131.209 144.175 136.850 1.00 143.81 ? 96  LEU B CD1 1 
ATOM 2089 C CD2 . LEU B 1 96  ? 131.786 141.750 136.952 1.00 150.88 ? 96  LEU B CD2 1 
ATOM 2090 N N   . ALA B 1 97  ? 126.473 141.768 137.113 1.00 148.76 ? 97  ALA B N   1 
ATOM 2091 C CA  . ALA B 1 97  ? 125.068 141.968 137.436 1.00 145.90 ? 97  ALA B CA  1 
ATOM 2092 C C   . ALA B 1 97  ? 124.304 140.662 137.593 1.00 144.14 ? 97  ALA B C   1 
ATOM 2093 O O   . ALA B 1 97  ? 123.195 140.682 138.138 1.00 143.96 ? 97  ALA B O   1 
ATOM 2094 C CB  . ALA B 1 97  ? 124.402 142.826 136.362 1.00 140.49 ? 97  ALA B CB  1 
ATOM 2095 N N   . HIS B 1 98  ? 124.868 139.540 137.146 1.00 142.83 ? 98  HIS B N   1 
ATOM 2096 C CA  . HIS B 1 98  ? 124.184 138.248 137.145 1.00 142.57 ? 98  HIS B CA  1 
ATOM 2097 C C   . HIS B 1 98  ? 122.828 138.357 136.452 1.00 140.73 ? 98  HIS B C   1 
ATOM 2098 O O   . HIS B 1 98  ? 121.777 138.088 137.037 1.00 143.03 ? 98  HIS B O   1 
ATOM 2099 C CB  . HIS B 1 98  ? 124.026 137.698 138.565 1.00 145.43 ? 98  HIS B CB  1 
ATOM 2100 C CG  . HIS B 1 98  ? 125.126 138.094 139.499 1.00 149.26 ? 98  HIS B CG  1 
ATOM 2101 N ND1 . HIS B 1 98  ? 126.409 137.603 139.389 1.00 152.34 ? 98  HIS B ND1 1 
ATOM 2102 C CD2 . HIS B 1 98  ? 125.131 138.922 140.570 1.00 147.03 ? 98  HIS B CD2 1 
ATOM 2103 C CE1 . HIS B 1 98  ? 127.159 138.118 140.347 1.00 152.39 ? 98  HIS B CE1 1 
ATOM 2104 N NE2 . HIS B 1 98  ? 126.407 138.920 141.078 1.00 149.90 ? 98  HIS B NE2 1 
ATOM 2105 N N   . SER B 1 99  ? 122.858 138.755 135.186 1.00 136.65 ? 99  SER B N   1 
ATOM 2106 C CA  . SER B 1 99  ? 121.646 139.042 134.438 1.00 126.65 ? 99  SER B CA  1 
ATOM 2107 C C   . SER B 1 99  ? 121.596 138.214 133.163 1.00 122.93 ? 99  SER B C   1 
ATOM 2108 O O   . SER B 1 99  ? 122.622 137.782 132.633 1.00 127.47 ? 99  SER B O   1 
ATOM 2109 C CB  . SER B 1 99  ? 121.553 140.530 134.094 1.00 123.30 ? 99  SER B CB  1 
ATOM 2110 O OG  . SER B 1 99  ? 120.639 140.753 133.037 1.00 123.18 ? 99  SER B OG  1 
ATOM 2111 N N   . LEU B 1 100 ? 120.376 137.992 132.678 1.00 118.37 ? 100 LEU B N   1 
ATOM 2112 C CA  . LEU B 1 100 ? 120.146 137.246 131.455 1.00 119.19 ? 100 LEU B CA  1 
ATOM 2113 C C   . LEU B 1 100 ? 119.565 138.083 130.327 1.00 124.78 ? 100 LEU B C   1 
ATOM 2114 O O   . LEU B 1 100 ? 119.738 137.713 129.162 1.00 129.90 ? 100 LEU B O   1 
ATOM 2115 C CB  . LEU B 1 100 ? 119.210 136.059 131.723 1.00 121.39 ? 100 LEU B CB  1 
ATOM 2116 C CG  . LEU B 1 100 ? 119.860 134.677 131.722 1.00 124.31 ? 100 LEU B CG  1 
ATOM 2117 C CD1 . LEU B 1 100 ? 121.089 134.670 132.611 1.00 117.52 ? 100 LEU B CD1 1 
ATOM 2118 C CD2 . LEU B 1 100 ? 118.867 133.627 132.175 1.00 128.73 ? 100 LEU B CD2 1 
ATOM 2119 N N   . ALA B 1 101 ? 118.880 139.187 130.631 1.00 121.17 ? 101 ALA B N   1 
ATOM 2120 C CA  . ALA B 1 101 ? 118.429 140.085 129.573 1.00 117.64 ? 101 ALA B CA  1 
ATOM 2121 C C   . ALA B 1 101 ? 119.612 140.721 128.858 1.00 118.79 ? 101 ALA B C   1 
ATOM 2122 O O   . ALA B 1 101 ? 119.597 140.889 127.633 1.00 125.26 ? 101 ALA B O   1 
ATOM 2123 C CB  . ALA B 1 101 ? 117.511 141.159 130.151 1.00 116.36 ? 101 ALA B CB  1 
ATOM 2124 N N   . ILE B 1 102 ? 120.651 141.082 129.608 1.00 114.20 ? 102 ILE B N   1 
ATOM 2125 C CA  . ILE B 1 102 ? 121.837 141.625 128.966 1.00 109.78 ? 102 ILE B CA  1 
ATOM 2126 C C   . ILE B 1 102 ? 122.512 140.552 128.129 1.00 113.39 ? 102 ILE B C   1 
ATOM 2127 O O   . ILE B 1 102 ? 123.160 140.856 127.122 1.00 119.52 ? 102 ILE B O   1 
ATOM 2128 C CB  . ILE B 1 102 ? 122.773 142.223 130.026 1.00 110.72 ? 102 ILE B CB  1 
ATOM 2129 C CG1 . ILE B 1 102 ? 121.932 143.003 131.035 1.00 112.03 ? 102 ILE B CG1 1 
ATOM 2130 C CG2 . ILE B 1 102 ? 123.808 143.115 129.378 1.00 122.79 ? 102 ILE B CG2 1 
ATOM 2131 C CD1 . ILE B 1 102 ? 121.644 144.422 130.629 1.00 117.25 ? 102 ILE B CD1 1 
ATOM 2132 N N   . MET B 1 103 ? 122.348 139.283 128.502 1.00 114.25 ? 103 MET B N   1 
ATOM 2133 C CA  . MET B 1 103 ? 122.808 138.198 127.642 1.00 116.92 ? 103 MET B CA  1 
ATOM 2134 C C   . MET B 1 103 ? 122.047 138.156 126.324 1.00 120.81 ? 103 MET B C   1 
ATOM 2135 O O   . MET B 1 103 ? 122.639 137.871 125.281 1.00 125.12 ? 103 MET B O   1 
ATOM 2136 C CB  . MET B 1 103 ? 122.711 136.860 128.369 1.00 117.88 ? 103 MET B CB  1 
ATOM 2137 C CG  . MET B 1 103 ? 123.654 136.708 129.546 1.00 124.26 ? 103 MET B CG  1 
ATOM 2138 S SD  . MET B 1 103 ? 125.091 137.785 129.413 1.00 132.03 ? 103 MET B SD  1 
ATOM 2139 C CE  . MET B 1 103 ? 125.391 138.160 131.131 1.00 131.28 ? 103 MET B CE  1 
ATOM 2140 N N   . THR B 1 104 ? 120.738 138.423 126.331 1.00 119.67 ? 104 THR B N   1 
ATOM 2141 C CA  . THR B 1 104 ? 120.028 138.455 125.053 1.00 120.35 ? 104 THR B CA  1 
ATOM 2142 C C   . THR B 1 104 ? 120.412 139.680 124.231 1.00 122.80 ? 104 THR B C   1 
ATOM 2143 O O   . THR B 1 104 ? 120.457 139.607 122.996 1.00 129.04 ? 104 THR B O   1 
ATOM 2144 C CB  . THR B 1 104 ? 118.513 138.401 125.257 1.00 122.86 ? 104 THR B CB  1 
ATOM 2145 O OG1 . THR B 1 104 ? 118.095 139.443 126.140 1.00 124.05 ? 104 THR B OG1 1 
ATOM 2146 C CG2 . THR B 1 104 ? 118.106 137.063 125.836 1.00 124.76 ? 104 THR B CG2 1 
ATOM 2147 N N   . ASP B 1 105 ? 120.703 140.804 124.888 1.00 120.82 ? 105 ASP B N   1 
ATOM 2148 C CA  . ASP B 1 105 ? 121.264 141.944 124.168 1.00 117.82 ? 105 ASP B CA  1 
ATOM 2149 C C   . ASP B 1 105 ? 122.583 141.567 123.505 1.00 119.16 ? 105 ASP B C   1 
ATOM 2150 O O   . ASP B 1 105 ? 122.821 141.877 122.330 1.00 125.02 ? 105 ASP B O   1 
ATOM 2151 C CB  . ASP B 1 105 ? 121.466 143.117 125.124 1.00 117.26 ? 105 ASP B CB  1 
ATOM 2152 C CG  . ASP B 1 105 ? 120.343 144.118 125.058 1.00 125.22 ? 105 ASP B CG  1 
ATOM 2153 O OD1 . ASP B 1 105 ? 120.524 145.249 125.552 1.00 124.26 ? 105 ASP B OD1 1 
ATOM 2154 O OD2 . ASP B 1 105 ? 119.276 143.772 124.512 1.00 133.22 ? 105 ASP B OD2 1 
ATOM 2155 N N   . ALA B 1 106 ? 123.450 140.883 124.251 1.00 118.23 ? 106 ALA B N   1 
ATOM 2156 C CA  . ALA B 1 106 ? 124.719 140.434 123.697 1.00 118.98 ? 106 ALA B CA  1 
ATOM 2157 C C   . ALA B 1 106 ? 124.514 139.418 122.586 1.00 124.96 ? 106 ALA B C   1 
ATOM 2158 O O   . ALA B 1 106 ? 125.304 139.372 121.644 1.00 133.27 ? 106 ALA B O   1 
ATOM 2159 C CB  . ALA B 1 106 ? 125.596 139.847 124.801 1.00 118.53 ? 106 ALA B CB  1 
ATOM 2160 N N   . ALA B 1 107 ? 123.465 138.599 122.671 1.00 121.64 ? 107 ALA B N   1 
ATOM 2161 C CA  . ALA B 1 107 ? 123.187 137.637 121.609 1.00 123.29 ? 107 ALA B CA  1 
ATOM 2162 C C   . ALA B 1 107 ? 122.737 138.334 120.332 1.00 127.63 ? 107 ALA B C   1 
ATOM 2163 O O   . ALA B 1 107 ? 123.134 137.943 119.228 1.00 131.77 ? 107 ALA B O   1 
ATOM 2164 C CB  . ALA B 1 107 ? 122.134 136.634 122.072 1.00 118.42 ? 107 ALA B CB  1 
ATOM 2165 N N   . HIS B 1 108 ? 121.898 139.363 120.460 1.00 126.17 ? 108 HIS B N   1 
ATOM 2166 C CA  . HIS B 1 108 ? 121.515 140.147 119.290 1.00 126.08 ? 108 HIS B CA  1 
ATOM 2167 C C   . HIS B 1 108 ? 122.738 140.810 118.666 1.00 129.91 ? 108 HIS B C   1 
ATOM 2168 O O   . HIS B 1 108 ? 122.927 140.788 117.439 1.00 133.01 ? 108 HIS B O   1 
ATOM 2169 C CB  . HIS B 1 108 ? 120.482 141.200 119.684 1.00 127.24 ? 108 HIS B CB  1 
ATOM 2170 C CG  . HIS B 1 108 ? 119.067 140.799 119.412 1.00 130.58 ? 108 HIS B CG  1 
ATOM 2171 N ND1 . HIS B 1 108 ? 118.451 141.017 118.198 1.00 135.84 ? 108 HIS B ND1 1 
ATOM 2172 C CD2 . HIS B 1 108 ? 118.135 140.225 120.208 1.00 131.58 ? 108 HIS B CD2 1 
ATOM 2173 C CE1 . HIS B 1 108 ? 117.206 140.579 118.253 1.00 135.12 ? 108 HIS B CE1 1 
ATOM 2174 N NE2 . HIS B 1 108 ? 116.988 140.097 119.463 1.00 132.45 ? 108 HIS B NE2 1 
ATOM 2175 N N   . LEU B 1 109 ? 123.591 141.400 119.508 1.00 129.57 ? 109 LEU B N   1 
ATOM 2176 C CA  . LEU B 1 109 ? 124.824 141.996 119.008 1.00 131.16 ? 109 LEU B CA  1 
ATOM 2177 C C   . LEU B 1 109 ? 125.717 140.944 118.365 1.00 134.58 ? 109 LEU B C   1 
ATOM 2178 O O   . LEU B 1 109 ? 126.414 141.226 117.386 1.00 140.17 ? 109 LEU B O   1 
ATOM 2179 C CB  . LEU B 1 109 ? 125.562 142.706 120.140 1.00 131.30 ? 109 LEU B CB  1 
ATOM 2180 C CG  . LEU B 1 109 ? 126.222 144.038 119.785 1.00 133.18 ? 109 LEU B CG  1 
ATOM 2181 C CD1 . LEU B 1 109 ? 125.220 144.975 119.134 1.00 134.69 ? 109 LEU B CD1 1 
ATOM 2182 C CD2 . LEU B 1 109 ? 126.840 144.676 121.016 1.00 139.22 ? 109 LEU B CD2 1 
ATOM 2183 N N   . LEU B 1 110 ? 125.716 139.728 118.910 1.00 131.51 ? 110 LEU B N   1 
ATOM 2184 C CA  . LEU B 1 110 ? 126.510 138.650 118.338 1.00 131.82 ? 110 LEU B CA  1 
ATOM 2185 C C   . LEU B 1 110 ? 126.011 138.294 116.951 1.00 137.58 ? 110 LEU B C   1 
ATOM 2186 O O   . LEU B 1 110 ? 126.810 138.074 116.039 1.00 144.99 ? 110 LEU B O   1 
ATOM 2187 C CB  . LEU B 1 110 ? 126.485 137.433 119.270 1.00 131.59 ? 110 LEU B CB  1 
ATOM 2188 C CG  . LEU B 1 110 ? 127.119 136.071 118.945 1.00 133.88 ? 110 LEU B CG  1 
ATOM 2189 C CD1 . LEU B 1 110 ? 127.133 135.237 120.208 1.00 136.67 ? 110 LEU B CD1 1 
ATOM 2190 C CD2 . LEU B 1 110 ? 126.385 135.299 117.865 1.00 127.89 ? 110 LEU B CD2 1 
ATOM 2191 N N   . ALA B 1 111 ? 124.694 138.218 116.776 1.00 135.86 ? 111 ALA B N   1 
ATOM 2192 C CA  . ALA B 1 111 ? 124.154 137.947 115.448 1.00 137.02 ? 111 ALA B CA  1 
ATOM 2193 C C   . ALA B 1 111 ? 124.546 139.043 114.469 1.00 141.51 ? 111 ALA B C   1 
ATOM 2194 O O   . ALA B 1 111 ? 124.955 138.760 113.334 1.00 143.43 ? 111 ALA B O   1 
ATOM 2195 C CB  . ALA B 1 111 ? 122.635 137.801 115.514 1.00 133.62 ? 111 ALA B CB  1 
ATOM 2196 N N   . ASP B 1 112 ? 124.459 140.303 114.903 1.00 141.93 ? 112 ASP B N   1 
ATOM 2197 C CA  . ASP B 1 112 ? 124.790 141.418 114.017 1.00 145.30 ? 112 ASP B CA  1 
ATOM 2198 C C   . ASP B 1 112 ? 126.267 141.367 113.625 1.00 147.35 ? 112 ASP B C   1 
ATOM 2199 O O   . ASP B 1 112 ? 126.609 141.450 112.437 1.00 149.73 ? 112 ASP B O   1 
ATOM 2200 C CB  . ASP B 1 112 ? 124.396 142.738 114.714 1.00 147.75 ? 112 ASP B CB  1 
ATOM 2201 C CG  . ASP B 1 112 ? 125.094 144.001 114.160 1.00 155.84 ? 112 ASP B CG  1 
ATOM 2202 O OD1 . ASP B 1 112 ? 124.659 145.101 114.563 1.00 157.40 ? 112 ASP B OD1 1 
ATOM 2203 O OD2 . ASP B 1 112 ? 126.016 143.954 113.326 1.00 156.00 ? 112 ASP B OD2 1 
ATOM 2204 N N   . VAL B 1 113 ? 127.158 141.215 114.609 1.00 145.47 ? 113 VAL B N   1 
ATOM 2205 C CA  . VAL B 1 113 ? 128.585 141.213 114.308 1.00 144.59 ? 113 VAL B CA  1 
ATOM 2206 C C   . VAL B 1 113 ? 128.976 139.963 113.535 1.00 145.97 ? 113 VAL B C   1 
ATOM 2207 O O   . VAL B 1 113 ? 129.906 140.002 112.727 1.00 153.85 ? 113 VAL B O   1 
ATOM 2208 C CB  . VAL B 1 113 ? 129.431 141.371 115.588 1.00 142.33 ? 113 VAL B CB  1 
ATOM 2209 C CG1 . VAL B 1 113 ? 129.061 142.657 116.313 1.00 146.15 ? 113 VAL B CG1 1 
ATOM 2210 C CG2 . VAL B 1 113 ? 129.288 140.160 116.497 1.00 141.41 ? 113 VAL B CG2 1 
ATOM 2211 N N   . GLY B 1 114 ? 128.290 138.840 113.753 1.00 142.12 ? 114 GLY B N   1 
ATOM 2212 C CA  . GLY B 1 114 ? 128.556 137.661 112.950 1.00 143.85 ? 114 GLY B CA  1 
ATOM 2213 C C   . GLY B 1 114 ? 128.171 137.862 111.499 1.00 147.63 ? 114 GLY B C   1 
ATOM 2214 O O   . GLY B 1 114 ? 128.901 137.453 110.593 1.00 151.65 ? 114 GLY B O   1 
ATOM 2215 N N   . SER B 1 115 ? 127.028 138.508 111.257 1.00 146.40 ? 115 SER B N   1 
ATOM 2216 C CA  . SER B 1 115 ? 126.659 138.845 109.887 1.00 149.74 ? 115 SER B CA  1 
ATOM 2217 C C   . SER B 1 115 ? 127.687 139.777 109.256 1.00 154.22 ? 115 SER B C   1 
ATOM 2218 O O   . SER B 1 115 ? 128.092 139.580 108.103 1.00 155.62 ? 115 SER B O   1 
ATOM 2219 C CB  . SER B 1 115 ? 125.269 139.480 109.858 1.00 149.28 ? 115 SER B CB  1 
ATOM 2220 O OG  . SER B 1 115 ? 125.136 140.366 108.760 1.00 152.59 ? 115 SER B OG  1 
ATOM 2221 N N   . MET B 1 116 ? 128.131 140.791 110.002 1.00 152.87 ? 116 MET B N   1 
ATOM 2222 C CA  . MET B 1 116 ? 129.114 141.727 109.459 1.00 149.69 ? 116 MET B CA  1 
ATOM 2223 C C   . MET B 1 116 ? 130.442 141.036 109.168 1.00 150.36 ? 116 MET B C   1 
ATOM 2224 O O   . MET B 1 116 ? 131.066 141.283 108.130 1.00 152.62 ? 116 MET B O   1 
ATOM 2225 C CB  . MET B 1 116 ? 129.316 142.896 110.420 1.00 148.19 ? 116 MET B CB  1 
ATOM 2226 C CG  . MET B 1 116 ? 128.670 144.191 109.957 1.00 145.39 ? 116 MET B CG  1 
ATOM 2227 S SD  . MET B 1 116 ? 128.713 145.473 111.222 1.00 148.40 ? 116 MET B SD  1 
ATOM 2228 C CE  . MET B 1 116 ? 130.337 145.188 111.915 1.00 143.44 ? 116 MET B CE  1 
ATOM 2229 N N   . MET B 1 117 ? 130.893 140.170 110.077 1.00 151.21 ? 117 MET B N   1 
ATOM 2230 C CA  . MET B 1 117 ? 132.145 139.452 109.873 1.00 153.74 ? 117 MET B CA  1 
ATOM 2231 C C   . MET B 1 117 ? 132.046 138.494 108.695 1.00 153.99 ? 117 MET B C   1 
ATOM 2232 O O   . MET B 1 117 ? 133.000 138.357 107.921 1.00 154.35 ? 117 MET B O   1 
ATOM 2233 C CB  . MET B 1 117 ? 132.533 138.699 111.149 1.00 155.18 ? 117 MET B CB  1 
ATOM 2234 C CG  . MET B 1 117 ? 134.030 138.685 111.480 1.00 161.13 ? 117 MET B CG  1 
ATOM 2235 S SD  . MET B 1 117 ? 134.975 140.232 111.616 1.00 181.06 ? 117 MET B SD  1 
ATOM 2236 C CE  . MET B 1 117 ? 133.744 141.476 112.012 1.00 161.06 ? 117 MET B CE  1 
ATOM 2237 N N   . GLY B 1 118 ? 130.907 137.816 108.548 1.00 153.08 ? 118 GLY B N   1 
ATOM 2238 C CA  . GLY B 1 118 ? 130.715 136.965 107.389 1.00 150.77 ? 118 GLY B CA  1 
ATOM 2239 C C   . GLY B 1 118 ? 130.737 137.750 106.093 1.00 152.31 ? 118 GLY B C   1 
ATOM 2240 O O   . GLY B 1 118 ? 131.326 137.313 105.104 1.00 152.11 ? 118 GLY B O   1 
ATOM 2241 N N   . SER B 1 119 ? 130.106 138.927 106.086 1.00 151.51 ? 119 SER B N   1 
ATOM 2242 C CA  . SER B 1 119 ? 130.138 139.770 104.895 1.00 149.64 ? 119 SER B CA  1 
ATOM 2243 C C   . SER B 1 119 ? 131.558 140.215 104.570 1.00 149.80 ? 119 SER B C   1 
ATOM 2244 O O   . SER B 1 119 ? 131.967 140.205 103.404 1.00 148.90 ? 119 SER B O   1 
ATOM 2245 C CB  . SER B 1 119 ? 129.227 140.981 105.085 1.00 148.39 ? 119 SER B CB  1 
ATOM 2246 O OG  . SER B 1 119 ? 127.908 140.578 105.408 1.00 150.45 ? 119 SER B OG  1 
ATOM 2247 N N   . LEU B 1 120 ? 132.326 140.607 105.588 1.00 150.22 ? 120 LEU B N   1 
ATOM 2248 C CA  . LEU B 1 120 ? 133.700 141.041 105.352 1.00 150.62 ? 120 LEU B CA  1 
ATOM 2249 C C   . LEU B 1 120 ? 134.558 139.894 104.830 1.00 152.03 ? 120 LEU B C   1 
ATOM 2250 O O   . LEU B 1 120 ? 135.332 140.066 103.879 1.00 153.09 ? 120 LEU B O   1 
ATOM 2251 C CB  . LEU B 1 120 ? 134.282 141.631 106.640 1.00 152.60 ? 120 LEU B CB  1 
ATOM 2252 C CG  . LEU B 1 120 ? 135.753 142.050 106.770 1.00 154.87 ? 120 LEU B CG  1 
ATOM 2253 C CD1 . LEU B 1 120 ? 136.696 140.875 107.037 1.00 153.28 ? 120 LEU B CD1 1 
ATOM 2254 C CD2 . LEU B 1 120 ? 136.198 142.834 105.540 1.00 157.13 ? 120 LEU B CD2 1 
ATOM 2255 N N   . PHE B 1 121 ? 134.437 138.715 105.442 1.00 152.76 ? 121 PHE B N   1 
ATOM 2256 C CA  . PHE B 1 121 ? 135.205 137.562 104.990 1.00 151.72 ? 121 PHE B CA  1 
ATOM 2257 C C   . PHE B 1 121 ? 134.819 137.171 103.571 1.00 146.89 ? 121 PHE B C   1 
ATOM 2258 O O   . PHE B 1 121 ? 135.681 136.818 102.758 1.00 146.53 ? 121 PHE B O   1 
ATOM 2259 C CB  . PHE B 1 121 ? 134.996 136.391 105.948 1.00 153.75 ? 121 PHE B CB  1 
ATOM 2260 C CG  . PHE B 1 121 ? 135.976 135.274 105.764 1.00 154.03 ? 121 PHE B CG  1 
ATOM 2261 C CD1 . PHE B 1 121 ? 135.544 134.008 105.411 1.00 153.80 ? 121 PHE B CD1 1 
ATOM 2262 C CD2 . PHE B 1 121 ? 137.330 135.488 105.950 1.00 153.43 ? 121 PHE B CD2 1 
ATOM 2263 C CE1 . PHE B 1 121 ? 136.445 132.976 105.242 1.00 153.14 ? 121 PHE B CE1 1 
ATOM 2264 C CE2 . PHE B 1 121 ? 138.236 134.460 105.784 1.00 153.69 ? 121 PHE B CE2 1 
ATOM 2265 C CZ  . PHE B 1 121 ? 137.793 133.203 105.429 1.00 154.37 ? 121 PHE B CZ  1 
ATOM 2266 N N   . SER B 1 122 ? 133.525 137.234 103.254 1.00 145.91 ? 122 SER B N   1 
ATOM 2267 C CA  . SER B 1 122 ? 133.070 136.930 101.904 1.00 144.75 ? 122 SER B CA  1 
ATOM 2268 C C   . SER B 1 122 ? 133.612 137.934 100.896 1.00 146.57 ? 122 SER B C   1 
ATOM 2269 O O   . SER B 1 122 ? 133.994 137.560 99.782  1.00 146.94 ? 122 SER B O   1 
ATOM 2270 C CB  . SER B 1 122 ? 131.545 136.904 101.874 1.00 141.33 ? 122 SER B CB  1 
ATOM 2271 O OG  . SER B 1 122 ? 131.022 138.131 101.396 1.00 142.13 ? 122 SER B OG  1 
ATOM 2272 N N   . LEU B 1 123 ? 133.638 139.217 101.262 1.00 146.17 ? 123 LEU B N   1 
ATOM 2273 C CA  . LEU B 1 123 ? 134.202 140.225 100.371 1.00 144.11 ? 123 LEU B CA  1 
ATOM 2274 C C   . LEU B 1 123 ? 135.686 139.978 100.141 1.00 142.02 ? 123 LEU B C   1 
ATOM 2275 O O   . LEU B 1 123 ? 136.188 140.156 99.026  1.00 139.76 ? 123 LEU B O   1 
ATOM 2276 C CB  . LEU B 1 123 ? 133.969 141.622 100.944 1.00 146.01 ? 123 LEU B CB  1 
ATOM 2277 C CG  . LEU B 1 123 ? 134.424 142.798 100.077 1.00 146.54 ? 123 LEU B CG  1 
ATOM 2278 C CD1 . LEU B 1 123 ? 133.324 143.842 99.974  1.00 142.74 ? 123 LEU B CD1 1 
ATOM 2279 C CD2 . LEU B 1 123 ? 135.697 143.415 100.633 1.00 145.02 ? 123 LEU B CD2 1 
ATOM 2280 N N   . TRP B 1 124 ? 136.406 139.575 101.190 1.00 141.89 ? 124 TRP B N   1 
ATOM 2281 C CA  . TRP B 1 124 ? 137.818 139.244 101.022 1.00 141.02 ? 124 TRP B CA  1 
ATOM 2282 C C   . TRP B 1 124 ? 137.999 138.028 100.122 1.00 141.09 ? 124 TRP B C   1 
ATOM 2283 O O   . TRP B 1 124 ? 138.926 137.983 99.306  1.00 142.70 ? 124 TRP B O   1 
ATOM 2284 C CB  . TRP B 1 124 ? 138.472 138.999 102.380 1.00 143.54 ? 124 TRP B CB  1 
ATOM 2285 C CG  . TRP B 1 124 ? 139.875 138.495 102.263 1.00 148.16 ? 124 TRP B CG  1 
ATOM 2286 C CD1 . TRP B 1 124 ? 140.967 139.202 101.854 1.00 150.69 ? 124 TRP B CD1 1 
ATOM 2287 C CD2 . TRP B 1 124 ? 140.340 137.171 102.551 1.00 149.12 ? 124 TRP B CD2 1 
ATOM 2288 N NE1 . TRP B 1 124 ? 142.083 138.402 101.873 1.00 152.45 ? 124 TRP B NE1 1 
ATOM 2289 C CE2 . TRP B 1 124 ? 141.725 137.150 102.297 1.00 151.18 ? 124 TRP B CE2 1 
ATOM 2290 C CE3 . TRP B 1 124 ? 139.720 136.003 103.002 1.00 146.25 ? 124 TRP B CE3 1 
ATOM 2291 C CZ2 . TRP B 1 124 ? 142.499 136.008 102.479 1.00 148.47 ? 124 TRP B CZ2 1 
ATOM 2292 C CZ3 . TRP B 1 124 ? 140.491 134.870 103.181 1.00 146.11 ? 124 TRP B CZ3 1 
ATOM 2293 C CH2 . TRP B 1 124 ? 141.865 134.881 102.920 1.00 145.68 ? 124 TRP B CH2 1 
ATOM 2294 N N   . LEU B 1 125 ? 137.130 137.028 100.264 1.00 140.93 ? 125 LEU B N   1 
ATOM 2295 C CA  . LEU B 1 125 ? 137.269 135.800 99.489  1.00 138.73 ? 125 LEU B CA  1 
ATOM 2296 C C   . LEU B 1 125 ? 136.852 135.976 98.035  1.00 139.70 ? 125 LEU B C   1 
ATOM 2297 O O   . LEU B 1 125 ? 137.356 135.260 97.164  1.00 138.54 ? 125 LEU B O   1 
ATOM 2298 C CB  . LEU B 1 125 ? 136.447 134.681 100.127 1.00 132.72 ? 125 LEU B CB  1 
ATOM 2299 C CG  . LEU B 1 125 ? 137.200 133.727 101.052 1.00 131.89 ? 125 LEU B CG  1 
ATOM 2300 C CD1 . LEU B 1 125 ? 136.245 132.724 101.671 1.00 130.36 ? 125 LEU B CD1 1 
ATOM 2301 C CD2 . LEU B 1 125 ? 138.304 133.017 100.297 1.00 122.06 ? 125 LEU B CD2 1 
ATOM 2302 N N   . SER B 1 126 ? 135.943 136.912 97.755  1.00 141.86 ? 126 SER B N   1 
ATOM 2303 C CA  . SER B 1 126 ? 135.391 137.030 96.409  1.00 141.01 ? 126 SER B CA  1 
ATOM 2304 C C   . SER B 1 126 ? 136.455 137.381 95.378  1.00 141.34 ? 126 SER B C   1 
ATOM 2305 O O   . SER B 1 126 ? 136.359 136.955 94.222  1.00 141.59 ? 126 SER B O   1 
ATOM 2306 C CB  . SER B 1 126 ? 134.274 138.073 96.390  1.00 140.56 ? 126 SER B CB  1 
ATOM 2307 O OG  . SER B 1 126 ? 134.046 138.549 95.075  1.00 141.66 ? 126 SER B OG  1 
ATOM 2308 N N   . THR B 1 127 ? 137.471 138.153 95.766  1.00 138.85 ? 127 THR B N   1 
ATOM 2309 C CA  . THR B 1 127 ? 138.506 138.530 94.811  1.00 143.63 ? 127 THR B CA  1 
ATOM 2310 C C   . THR B 1 127 ? 139.360 137.343 94.384  1.00 146.79 ? 127 THR B C   1 
ATOM 2311 O O   . THR B 1 127 ? 140.020 137.415 93.342  1.00 149.75 ? 127 THR B O   1 
ATOM 2312 C CB  . THR B 1 127 ? 139.400 139.626 95.394  1.00 148.90 ? 127 THR B CB  1 
ATOM 2313 O OG1 . THR B 1 127 ? 140.354 140.040 94.409  1.00 159.46 ? 127 THR B OG1 1 
ATOM 2314 C CG2 . THR B 1 127 ? 140.144 139.115 96.615  1.00 142.29 ? 127 THR B CG2 1 
ATOM 2315 N N   . ARG B 1 128 ? 139.363 136.264 95.156  1.00 143.86 ? 128 ARG B N   1 
ATOM 2316 C CA  . ARG B 1 128 ? 140.152 135.094 94.795  1.00 139.91 ? 128 ARG B CA  1 
ATOM 2317 C C   . ARG B 1 128 ? 139.548 134.418 93.569  1.00 138.17 ? 128 ARG B C   1 
ATOM 2318 O O   . ARG B 1 128 ? 138.339 134.165 93.541  1.00 136.46 ? 128 ARG B O   1 
ATOM 2319 C CB  . ARG B 1 128 ? 140.222 134.115 95.961  1.00 132.67 ? 128 ARG B CB  1 
ATOM 2320 C CG  . ARG B 1 128 ? 141.234 134.500 97.025  1.00 134.55 ? 128 ARG B CG  1 
ATOM 2321 C CD  . ARG B 1 128 ? 141.185 133.545 98.203  1.00 135.70 ? 128 ARG B CD  1 
ATOM 2322 N NE  . ARG B 1 128 ? 142.055 132.391 98.013  1.00 134.54 ? 128 ARG B NE  1 
ATOM 2323 C CZ  . ARG B 1 128 ? 141.980 131.274 98.722  1.00 130.01 ? 128 ARG B CZ  1 
ATOM 2324 N NH1 . ARG B 1 128 ? 141.077 131.120 99.676  1.00 121.71 ? 128 ARG B NH1 1 
ATOM 2325 N NH2 . ARG B 1 128 ? 142.834 130.287 98.469  1.00 132.12 ? 128 ARG B NH2 1 
ATOM 2326 N N   . PRO B 1 129 ? 140.343 134.116 92.547  1.00 137.80 ? 129 PRO B N   1 
ATOM 2327 C CA  . PRO B 1 129 ? 139.791 133.496 91.340  1.00 133.33 ? 129 PRO B CA  1 
ATOM 2328 C C   . PRO B 1 129 ? 139.358 132.062 91.595  1.00 128.06 ? 129 PRO B C   1 
ATOM 2329 O O   . PRO B 1 129 ? 139.825 131.393 92.519  1.00 126.69 ? 129 PRO B O   1 
ATOM 2330 C CB  . PRO B 1 129 ? 140.955 133.555 90.348  1.00 133.42 ? 129 PRO B CB  1 
ATOM 2331 C CG  . PRO B 1 129 ? 142.168 133.547 91.208  1.00 138.08 ? 129 PRO B CG  1 
ATOM 2332 C CD  . PRO B 1 129 ? 141.802 134.291 92.464  1.00 138.47 ? 129 PRO B CD  1 
ATOM 2333 N N   . ALA B 1 130 ? 138.442 131.596 90.750  1.00 125.39 ? 130 ALA B N   1 
ATOM 2334 C CA  . ALA B 1 130 ? 137.953 130.229 90.850  1.00 114.50 ? 130 ALA B CA  1 
ATOM 2335 C C   . ALA B 1 130 ? 139.065 129.245 90.513  1.00 116.13 ? 130 ALA B C   1 
ATOM 2336 O O   . ALA B 1 130 ? 139.767 129.404 89.510  1.00 119.17 ? 130 ALA B O   1 
ATOM 2337 C CB  . ALA B 1 130 ? 136.763 130.025 89.916  1.00 102.55 ? 130 ALA B CB  1 
ATOM 2338 N N   . THR B 1 131 ? 139.222 128.226 91.351  1.00 113.35 ? 131 THR B N   1 
ATOM 2339 C CA  . THR B 1 131 ? 140.268 127.233 91.165  1.00 112.13 ? 131 THR B CA  1 
ATOM 2340 C C   . THR B 1 131 ? 139.717 126.047 90.377  1.00 102.83 ? 131 THR B C   1 
ATOM 2341 O O   . THR B 1 131 ? 138.572 126.050 89.920  1.00 98.29  ? 131 THR B O   1 
ATOM 2342 C CB  . THR B 1 131 ? 140.834 126.797 92.515  1.00 109.77 ? 131 THR B CB  1 
ATOM 2343 O OG1 . THR B 1 131 ? 139.768 126.345 93.358  1.00 105.62 ? 131 THR B OG1 1 
ATOM 2344 C CG2 . THR B 1 131 ? 141.547 127.954 93.190  1.00 111.26 ? 131 THR B CG2 1 
ATOM 2345 N N   . ARG B 1 132 ? 140.539 125.014 90.207  1.00 102.73 ? 132 ARG B N   1 
ATOM 2346 C CA  . ARG B 1 132 ? 140.114 123.805 89.519  1.00 96.09  ? 132 ARG B CA  1 
ATOM 2347 C C   . ARG B 1 132 ? 139.293 122.883 90.407  1.00 95.61  ? 132 ARG B C   1 
ATOM 2348 O O   . ARG B 1 132 ? 138.716 121.917 89.900  1.00 100.73 ? 132 ARG B O   1 
ATOM 2349 C CB  . ARG B 1 132 ? 141.333 123.061 88.976  1.00 99.18  ? 132 ARG B CB  1 
ATOM 2350 C CG  . ARG B 1 132 ? 142.254 123.949 88.158  1.00 109.28 ? 132 ARG B CG  1 
ATOM 2351 C CD  . ARG B 1 132 ? 143.376 123.162 87.514  1.00 115.75 ? 132 ARG B CD  1 
ATOM 2352 N NE  . ARG B 1 132 ? 143.541 121.848 88.122  1.00 123.04 ? 132 ARG B NE  1 
ATOM 2353 C CZ  . ARG B 1 132 ? 144.272 120.873 87.601  1.00 130.01 ? 132 ARG B CZ  1 
ATOM 2354 N NH1 . ARG B 1 132 ? 144.948 121.042 86.477  1.00 125.86 ? 132 ARG B NH1 1 
ATOM 2355 N NH2 . ARG B 1 132 ? 144.333 119.702 88.228  1.00 130.98 ? 132 ARG B NH2 1 
ATOM 2356 N N   . THR B 1 133 ? 139.237 123.148 91.711  1.00 95.59  ? 133 THR B N   1 
ATOM 2357 C CA  . THR B 1 133 ? 138.365 122.418 92.616  1.00 95.60  ? 133 THR B CA  1 
ATOM 2358 C C   . THR B 1 133 ? 137.154 123.224 93.056  1.00 95.26  ? 133 THR B C   1 
ATOM 2359 O O   . THR B 1 133 ? 136.288 122.680 93.746  1.00 94.06  ? 133 THR B O   1 
ATOM 2360 C CB  . THR B 1 133 ? 139.139 121.959 93.860  1.00 98.81  ? 133 THR B CB  1 
ATOM 2361 O OG1 . THR B 1 133 ? 139.095 122.986 94.857  1.00 102.32 ? 133 THR B OG1 1 
ATOM 2362 C CG2 . THR B 1 133 ? 140.586 121.665 93.509  1.00 98.47  ? 133 THR B CG2 1 
ATOM 2363 N N   . MET B 1 134 ? 137.078 124.504 92.693  1.00 95.22  ? 134 MET B N   1 
ATOM 2364 C CA  . MET B 1 134 ? 135.914 125.352 92.950  1.00 92.67  ? 134 MET B CA  1 
ATOM 2365 C C   . MET B 1 134 ? 135.616 126.073 91.641  1.00 95.31  ? 134 MET B C   1 
ATOM 2366 O O   . MET B 1 134 ? 136.096 127.186 91.412  1.00 96.41  ? 134 MET B O   1 
ATOM 2367 C CB  . MET B 1 134 ? 136.170 126.328 94.091  1.00 89.88  ? 134 MET B CB  1 
ATOM 2368 C CG  . MET B 1 134 ? 136.309 125.675 95.450  1.00 91.75  ? 134 MET B CG  1 
ATOM 2369 S SD  . MET B 1 134 ? 134.807 125.821 96.429  1.00 99.72  ? 134 MET B SD  1 
ATOM 2370 C CE  . MET B 1 134 ? 135.144 124.650 97.737  1.00 93.24  ? 134 MET B CE  1 
ATOM 2371 N N   . THR B 1 135 ? 134.817 125.435 90.786  1.00 92.64  ? 135 THR B N   1 
ATOM 2372 C CA  . THR B 1 135 ? 134.595 125.948 89.441  1.00 86.83  ? 135 THR B CA  1 
ATOM 2373 C C   . THR B 1 135 ? 133.713 127.187 89.420  1.00 88.24  ? 135 THR B C   1 
ATOM 2374 O O   . THR B 1 135 ? 133.715 127.915 88.423  1.00 85.58  ? 135 THR B O   1 
ATOM 2375 C CB  . THR B 1 135 ? 133.979 124.860 88.568  1.00 82.38  ? 135 THR B CB  1 
ATOM 2376 O OG1 . THR B 1 135 ? 133.029 124.117 89.340  1.00 85.39  ? 135 THR B OG1 1 
ATOM 2377 C CG2 . THR B 1 135 ? 135.055 123.917 88.064  1.00 79.81  ? 135 THR B CG2 1 
ATOM 2378 N N   . PHE B 1 136 ? 132.959 127.440 90.486  1.00 91.09  ? 136 PHE B N   1 
ATOM 2379 C CA  . PHE B 1 136 ? 132.100 128.612 90.566  1.00 89.25  ? 136 PHE B CA  1 
ATOM 2380 C C   . PHE B 1 136 ? 132.727 129.761 91.339  1.00 93.95  ? 136 PHE B C   1 
ATOM 2381 O O   . PHE B 1 136 ? 132.228 130.887 91.254  1.00 96.51  ? 136 PHE B O   1 
ATOM 2382 C CB  . PHE B 1 136 ? 130.764 128.243 91.215  1.00 87.95  ? 136 PHE B CB  1 
ATOM 2383 C CG  . PHE B 1 136 ? 129.780 127.638 90.265  1.00 90.07  ? 136 PHE B CG  1 
ATOM 2384 C CD1 . PHE B 1 136 ? 129.172 128.409 89.295  1.00 88.24  ? 136 PHE B CD1 1 
ATOM 2385 C CD2 . PHE B 1 136 ? 129.467 126.296 90.339  1.00 89.76  ? 136 PHE B CD2 1 
ATOM 2386 C CE1 . PHE B 1 136 ? 128.269 127.854 88.420  1.00 81.43  ? 136 PHE B CE1 1 
ATOM 2387 C CE2 . PHE B 1 136 ? 128.566 125.738 89.468  1.00 87.00  ? 136 PHE B CE2 1 
ATOM 2388 C CZ  . PHE B 1 136 ? 127.966 126.517 88.507  1.00 81.26  ? 136 PHE B CZ  1 
ATOM 2389 N N   . GLY B 1 137 ? 133.796 129.509 92.085  1.00 97.14  ? 137 GLY B N   1 
ATOM 2390 C CA  . GLY B 1 137 ? 134.397 130.537 92.906  1.00 97.52  ? 137 GLY B CA  1 
ATOM 2391 C C   . GLY B 1 137 ? 134.130 130.300 94.375  1.00 97.70  ? 137 GLY B C   1 
ATOM 2392 O O   . GLY B 1 137 ? 134.020 129.151 94.810  1.00 100.37 ? 137 GLY B O   1 
ATOM 2393 N N   . TRP B 1 138 ? 134.008 131.375 95.149  1.00 94.85  ? 138 TRP B N   1 
ATOM 2394 C CA  . TRP B 1 138 ? 133.773 131.270 96.582  1.00 94.98  ? 138 TRP B CA  1 
ATOM 2395 C C   . TRP B 1 138 ? 132.570 132.101 97.004  1.00 100.68 ? 138 TRP B C   1 
ATOM 2396 O O   . TRP B 1 138 ? 132.563 132.686 98.088  1.00 108.42 ? 138 TRP B O   1 
ATOM 2397 C CB  . TRP B 1 138 ? 135.012 131.691 97.369  1.00 103.36 ? 138 TRP B CB  1 
ATOM 2398 C CG  . TRP B 1 138 ? 136.261 131.009 96.929  1.00 103.11 ? 138 TRP B CG  1 
ATOM 2399 C CD1 . TRP B 1 138 ? 136.998 131.284 95.817  1.00 104.67 ? 138 TRP B CD1 1 
ATOM 2400 C CD2 . TRP B 1 138 ? 136.928 129.939 97.599  1.00 99.41  ? 138 TRP B CD2 1 
ATOM 2401 N NE1 . TRP B 1 138 ? 138.082 130.445 95.750  1.00 105.62 ? 138 TRP B NE1 1 
ATOM 2402 C CE2 . TRP B 1 138 ? 138.061 129.610 96.834  1.00 100.49 ? 138 TRP B CE2 1 
ATOM 2403 C CE3 . TRP B 1 138 ? 136.676 129.225 98.772  1.00 97.91  ? 138 TRP B CE3 1 
ATOM 2404 C CZ2 . TRP B 1 138 ? 138.940 128.599 97.204  1.00 102.40 ? 138 TRP B CZ2 1 
ATOM 2405 C CZ3 . TRP B 1 138 ? 137.547 128.223 99.137  1.00 102.96 ? 138 TRP B CZ3 1 
ATOM 2406 C CH2 . TRP B 1 138 ? 138.666 127.918 98.357  1.00 105.68 ? 138 TRP B CH2 1 
ATOM 2407 N N   . HIS B 1 139 ? 131.541 132.156 96.163  1.00 97.97  ? 139 HIS B N   1 
ATOM 2408 C CA  . HIS B 1 139 ? 130.386 132.994 96.444  1.00 98.69  ? 139 HIS B CA  1 
ATOM 2409 C C   . HIS B 1 139 ? 129.402 132.355 97.413  1.00 103.61 ? 139 HIS B C   1 
ATOM 2410 O O   . HIS B 1 139 ? 128.446 133.019 97.822  1.00 107.56 ? 139 HIS B O   1 
ATOM 2411 C CB  . HIS B 1 139 ? 129.673 133.346 95.141  1.00 95.86  ? 139 HIS B CB  1 
ATOM 2412 C CG  . HIS B 1 139 ? 130.565 133.989 94.128  1.00 99.84  ? 139 HIS B CG  1 
ATOM 2413 N ND1 . HIS B 1 139 ? 131.133 135.229 94.318  1.00 109.66 ? 139 HIS B ND1 1 
ATOM 2414 C CD2 . HIS B 1 139 ? 130.991 133.562 92.916  1.00 103.16 ? 139 HIS B CD2 1 
ATOM 2415 C CE1 . HIS B 1 139 ? 131.869 135.540 93.266  1.00 115.96 ? 139 HIS B CE1 1 
ATOM 2416 N NE2 . HIS B 1 139 ? 131.799 134.545 92.400  1.00 108.57 ? 139 HIS B NE2 1 
ATOM 2417 N N   . ARG B 1 140 ? 129.602 131.094 97.785  1.00 99.12  ? 140 ARG B N   1 
ATOM 2418 C CA  . ARG B 1 140 ? 128.761 130.465 98.793  1.00 96.13  ? 140 ARG B CA  1 
ATOM 2419 C C   . ARG B 1 140 ? 129.220 130.779 100.208 1.00 101.34 ? 140 ARG B C   1 
ATOM 2420 O O   . ARG B 1 140 ? 128.566 130.352 101.169 1.00 104.30 ? 140 ARG B O   1 
ATOM 2421 C CB  . ARG B 1 140 ? 128.729 128.952 98.580  1.00 93.50  ? 140 ARG B CB  1 
ATOM 2422 C CG  . ARG B 1 140 ? 127.770 128.508 97.494  1.00 91.23  ? 140 ARG B CG  1 
ATOM 2423 C CD  . ARG B 1 140 ? 126.385 128.266 98.056  1.00 88.47  ? 140 ARG B CD  1 
ATOM 2424 N NE  . ARG B 1 140 ? 125.379 128.181 97.007  1.00 87.56  ? 140 ARG B NE  1 
ATOM 2425 C CZ  . ARG B 1 140 ? 124.855 127.048 96.563  1.00 87.97  ? 140 ARG B CZ  1 
ATOM 2426 N NH1 . ARG B 1 140 ? 125.222 125.878 97.054  1.00 89.21  ? 140 ARG B NH1 1 
ATOM 2427 N NH2 . ARG B 1 140 ? 123.936 127.091 95.603  1.00 89.45  ? 140 ARG B NH2 1 
ATOM 2428 N N   . SER B 1 141 ? 130.329 131.508 100.353 1.00 103.31 ? 141 SER B N   1 
ATOM 2429 C CA  . SER B 1 141 ? 130.789 131.905 101.676 1.00 105.11 ? 141 SER B CA  1 
ATOM 2430 C C   . SER B 1 141 ? 129.786 132.821 102.360 1.00 109.83 ? 141 SER B C   1 
ATOM 2431 O O   . SER B 1 141 ? 129.639 132.764 103.583 1.00 112.33 ? 141 SER B O   1 
ATOM 2432 C CB  . SER B 1 141 ? 132.151 132.588 101.577 1.00 110.28 ? 141 SER B CB  1 
ATOM 2433 O OG  . SER B 1 141 ? 132.113 133.666 100.661 1.00 115.47 ? 141 SER B OG  1 
ATOM 2434 N N   . GLU B 1 142 ? 129.090 133.667 101.596 1.00 107.20 ? 142 GLU B N   1 
ATOM 2435 C CA  . GLU B 1 142 ? 128.046 134.504 102.180 1.00 108.46 ? 142 GLU B CA  1 
ATOM 2436 C C   . GLU B 1 142 ? 126.995 133.650 102.875 1.00 109.66 ? 142 GLU B C   1 
ATOM 2437 O O   . GLU B 1 142 ? 126.668 133.869 104.048 1.00 112.02 ? 142 GLU B O   1 
ATOM 2438 C CB  . GLU B 1 142 ? 127.374 135.365 101.106 1.00 112.07 ? 142 GLU B CB  1 
ATOM 2439 C CG  . GLU B 1 142 ? 128.136 136.593 100.615 1.00 119.00 ? 142 GLU B CG  1 
ATOM 2440 C CD  . GLU B 1 142 ? 129.229 136.279 99.610  1.00 126.17 ? 142 GLU B CD  1 
ATOM 2441 O OE1 . GLU B 1 142 ? 129.494 135.092 99.345  1.00 120.06 ? 142 GLU B OE1 1 
ATOM 2442 O OE2 . GLU B 1 142 ? 129.817 137.235 99.064  1.00 136.33 ? 142 GLU B OE2 1 
ATOM 2443 N N   . THR B 1 143 ? 126.456 132.664 102.156 1.00 106.96 ? 143 THR B N   1 
ATOM 2444 C CA  . THR B 1 143 ? 125.411 131.816 102.714 1.00 103.70 ? 143 THR B CA  1 
ATOM 2445 C C   . THR B 1 143 ? 125.935 130.986 103.876 1.00 104.33 ? 143 THR B C   1 
ATOM 2446 O O   . THR B 1 143 ? 125.240 130.814 104.884 1.00 107.73 ? 143 THR B O   1 
ATOM 2447 C CB  . THR B 1 143 ? 124.836 130.914 101.626 1.00 102.12 ? 143 THR B CB  1 
ATOM 2448 O OG1 . THR B 1 143 ? 124.563 131.693 100.457 1.00 102.59 ? 143 THR B OG1 1 
ATOM 2449 C CG2 . THR B 1 143 ? 123.553 130.267 102.103 1.00 102.14 ? 143 THR B CG2 1 
ATOM 2450 N N   . LEU B 1 144 ? 127.156 130.462 103.757 1.00 104.21 ? 144 LEU B N   1 
ATOM 2451 C CA  . LEU B 1 144 ? 127.707 129.662 104.845 1.00 104.25 ? 144 LEU B CA  1 
ATOM 2452 C C   . LEU B 1 144 ? 127.910 130.502 106.100 1.00 105.35 ? 144 LEU B C   1 
ATOM 2453 O O   . LEU B 1 144 ? 127.616 130.050 107.212 1.00 109.53 ? 144 LEU B O   1 
ATOM 2454 C CB  . LEU B 1 144 ? 129.015 129.010 104.406 1.00 106.52 ? 144 LEU B CB  1 
ATOM 2455 C CG  . LEU B 1 144 ? 128.871 127.799 103.480 1.00 99.64  ? 144 LEU B CG  1 
ATOM 2456 C CD1 . LEU B 1 144 ? 130.073 126.889 103.620 1.00 104.93 ? 144 LEU B CD1 1 
ATOM 2457 C CD2 . LEU B 1 144 ? 127.590 127.034 103.761 1.00 91.45  ? 144 LEU B CD2 1 
ATOM 2458 N N   . GLY B 1 145 ? 128.397 131.734 105.944 1.00 102.98 ? 145 GLY B N   1 
ATOM 2459 C CA  . GLY B 1 145 ? 128.561 132.605 107.094 1.00 107.21 ? 145 GLY B CA  1 
ATOM 2460 C C   . GLY B 1 145 ? 127.239 133.000 107.720 1.00 109.40 ? 145 GLY B C   1 
ATOM 2461 O O   . GLY B 1 145 ? 127.121 133.070 108.946 1.00 112.03 ? 145 GLY B O   1 
ATOM 2462 N N   . ALA B 1 146 ? 126.226 133.265 106.891 1.00 106.92 ? 146 ALA B N   1 
ATOM 2463 C CA  . ALA B 1 146 ? 124.906 133.572 107.431 1.00 107.33 ? 146 ALA B CA  1 
ATOM 2464 C C   . ALA B 1 146 ? 124.345 132.391 108.211 1.00 106.80 ? 146 ALA B C   1 
ATOM 2465 O O   . ALA B 1 146 ? 123.780 132.563 109.300 1.00 109.92 ? 146 ALA B O   1 
ATOM 2466 C CB  . ALA B 1 146 ? 123.958 133.973 106.303 1.00 105.41 ? 146 ALA B CB  1 
ATOM 2467 N N   . LEU B 1 147 ? 124.502 131.180 107.674 1.00 103.83 ? 147 LEU B N   1 
ATOM 2468 C CA  . LEU B 1 147 ? 124.035 129.991 108.376 1.00 102.28 ? 147 LEU B CA  1 
ATOM 2469 C C   . LEU B 1 147 ? 124.782 129.796 109.689 1.00 108.41 ? 147 LEU B C   1 
ATOM 2470 O O   . LEU B 1 147 ? 124.180 129.433 110.705 1.00 110.47 ? 147 LEU B O   1 
ATOM 2471 C CB  . LEU B 1 147 ? 124.189 128.764 107.481 1.00 100.93 ? 147 LEU B CB  1 
ATOM 2472 C CG  . LEU B 1 147 ? 123.587 127.468 108.017 1.00 105.22 ? 147 LEU B CG  1 
ATOM 2473 C CD1 . LEU B 1 147 ? 122.084 127.604 108.148 1.00 105.30 ? 147 LEU B CD1 1 
ATOM 2474 C CD2 . LEU B 1 147 ? 123.944 126.307 107.112 1.00 104.10 ? 147 LEU B CD2 1 
ATOM 2475 N N   . ALA B 1 148 ? 126.096 130.027 109.685 1.00 108.89 ? 148 ALA B N   1 
ATOM 2476 C CA  . ALA B 1 148 ? 126.871 129.904 110.915 1.00 108.33 ? 148 ALA B CA  1 
ATOM 2477 C C   . ALA B 1 148 ? 126.424 130.924 111.954 1.00 113.68 ? 148 ALA B C   1 
ATOM 2478 O O   . ALA B 1 148 ? 126.323 130.607 113.145 1.00 120.41 ? 148 ALA B O   1 
ATOM 2479 C CB  . ALA B 1 148 ? 128.360 130.062 110.615 1.00 107.02 ? 148 ALA B CB  1 
ATOM 2480 N N   . SER B 1 149 ? 126.160 132.158 111.521 1.00 112.18 ? 149 SER B N   1 
ATOM 2481 C CA  . SER B 1 149 ? 125.689 133.179 112.450 1.00 113.50 ? 149 SER B CA  1 
ATOM 2482 C C   . SER B 1 149 ? 124.338 132.800 113.041 1.00 117.89 ? 149 SER B C   1 
ATOM 2483 O O   . SER B 1 149 ? 124.107 132.974 114.243 1.00 121.33 ? 149 SER B O   1 
ATOM 2484 C CB  . SER B 1 149 ? 125.614 134.533 111.747 1.00 116.09 ? 149 SER B CB  1 
ATOM 2485 O OG  . SER B 1 149 ? 124.323 134.768 111.218 1.00 118.76 ? 149 SER B OG  1 
ATOM 2486 N N   . VAL B 1 150 ? 123.435 132.268 112.215 1.00 117.14 ? 150 VAL B N   1 
ATOM 2487 C CA  . VAL B 1 150 ? 122.137 131.834 112.726 1.00 114.54 ? 150 VAL B CA  1 
ATOM 2488 C C   . VAL B 1 150 ? 122.308 130.690 113.719 1.00 117.11 ? 150 VAL B C   1 
ATOM 2489 O O   . VAL B 1 150 ? 121.655 130.654 114.770 1.00 121.35 ? 150 VAL B O   1 
ATOM 2490 C CB  . VAL B 1 150 ? 121.209 131.444 111.562 1.00 112.37 ? 150 VAL B CB  1 
ATOM 2491 C CG1 . VAL B 1 150 ? 119.973 130.740 112.084 1.00 113.17 ? 150 VAL B CG1 1 
ATOM 2492 C CG2 . VAL B 1 150 ? 120.821 132.677 110.768 1.00 111.53 ? 150 VAL B CG2 1 
ATOM 2493 N N   . VAL B 1 151 ? 123.190 129.740 113.406 1.00 116.50 ? 151 VAL B N   1 
ATOM 2494 C CA  . VAL B 1 151 ? 123.412 128.606 114.297 1.00 118.72 ? 151 VAL B CA  1 
ATOM 2495 C C   . VAL B 1 151 ? 123.955 129.079 115.640 1.00 120.79 ? 151 VAL B C   1 
ATOM 2496 O O   . VAL B 1 151 ? 123.533 128.600 116.698 1.00 122.48 ? 151 VAL B O   1 
ATOM 2497 C CB  . VAL B 1 151 ? 124.349 127.582 113.629 1.00 121.48 ? 151 VAL B CB  1 
ATOM 2498 C CG1 . VAL B 1 151 ? 125.133 126.803 114.673 1.00 125.37 ? 151 VAL B CG1 1 
ATOM 2499 C CG2 . VAL B 1 151 ? 123.551 126.641 112.746 1.00 119.55 ? 151 VAL B CG2 1 
ATOM 2500 N N   . SER B 1 152 ? 124.896 130.024 115.622 1.00 120.21 ? 152 SER B N   1 
ATOM 2501 C CA  . SER B 1 152 ? 125.429 130.553 116.874 1.00 119.44 ? 152 SER B CA  1 
ATOM 2502 C C   . SER B 1 152 ? 124.367 131.327 117.647 1.00 121.34 ? 152 SER B C   1 
ATOM 2503 O O   . SER B 1 152 ? 124.332 131.289 118.886 1.00 125.32 ? 152 SER B O   1 
ATOM 2504 C CB  . SER B 1 152 ? 126.643 131.434 116.591 1.00 121.98 ? 152 SER B CB  1 
ATOM 2505 O OG  . SER B 1 152 ? 126.249 132.680 116.050 1.00 126.00 ? 152 SER B OG  1 
ATOM 2506 N N   . LEU B 1 153 ? 123.497 132.046 116.940 1.00 122.53 ? 153 LEU B N   1 
ATOM 2507 C CA  . LEU B 1 153 ? 122.423 132.749 117.629 1.00 122.67 ? 153 LEU B CA  1 
ATOM 2508 C C   . LEU B 1 153 ? 121.491 131.767 118.326 1.00 120.99 ? 153 LEU B C   1 
ATOM 2509 O O   . LEU B 1 153 ? 121.058 132.010 119.456 1.00 120.51 ? 153 LEU B O   1 
ATOM 2510 C CB  . LEU B 1 153 ? 121.651 133.630 116.654 1.00 123.06 ? 153 LEU B CB  1 
ATOM 2511 C CG  . LEU B 1 153 ? 120.546 134.438 117.328 1.00 125.24 ? 153 LEU B CG  1 
ATOM 2512 C CD1 . LEU B 1 153 ? 121.134 135.313 118.418 1.00 129.22 ? 153 LEU B CD1 1 
ATOM 2513 C CD2 . LEU B 1 153 ? 119.827 135.281 116.314 1.00 127.67 ? 153 LEU B CD2 1 
ATOM 2514 N N   . TRP B 1 154 ? 121.179 130.647 117.672 1.00 121.42 ? 154 TRP B N   1 
ATOM 2515 C CA  . TRP B 1 154 ? 120.354 129.628 118.321 1.00 120.41 ? 154 TRP B CA  1 
ATOM 2516 C C   . TRP B 1 154 ? 121.095 128.945 119.467 1.00 120.82 ? 154 TRP B C   1 
ATOM 2517 O O   . TRP B 1 154 ? 120.479 128.581 120.473 1.00 120.28 ? 154 TRP B O   1 
ATOM 2518 C CB  . TRP B 1 154 ? 119.856 128.611 117.295 1.00 122.99 ? 154 TRP B CB  1 
ATOM 2519 C CG  . TRP B 1 154 ? 118.836 129.176 116.348 1.00 128.06 ? 154 TRP B CG  1 
ATOM 2520 C CD1 . TRP B 1 154 ? 118.943 130.313 115.605 1.00 129.44 ? 154 TRP B CD1 1 
ATOM 2521 C CD2 . TRP B 1 154 ? 117.555 128.617 116.038 1.00 136.98 ? 154 TRP B CD2 1 
ATOM 2522 N NE1 . TRP B 1 154 ? 117.808 130.503 114.858 1.00 134.37 ? 154 TRP B NE1 1 
ATOM 2523 C CE2 . TRP B 1 154 ? 116.939 129.473 115.105 1.00 141.62 ? 154 TRP B CE2 1 
ATOM 2524 C CE3 . TRP B 1 154 ? 116.867 127.476 116.462 1.00 141.65 ? 154 TRP B CE3 1 
ATOM 2525 C CZ2 . TRP B 1 154 ? 115.670 129.226 114.587 1.00 149.80 ? 154 TRP B CZ2 1 
ATOM 2526 C CZ3 . TRP B 1 154 ? 115.606 127.232 115.947 1.00 148.04 ? 154 TRP B CZ3 1 
ATOM 2527 C CH2 . TRP B 1 154 ? 115.021 128.103 115.020 1.00 151.39 ? 154 TRP B CH2 1 
ATOM 2528 N N   . MET B 1 155 ? 122.409 128.748 119.330 1.00 121.97 ? 155 MET B N   1 
ATOM 2529 C CA  . MET B 1 155 ? 123.267 128.385 120.455 1.00 122.26 ? 155 MET B CA  1 
ATOM 2530 C C   . MET B 1 155 ? 122.951 129.219 121.690 1.00 119.00 ? 155 MET B C   1 
ATOM 2531 O O   . MET B 1 155 ? 122.508 128.705 122.730 1.00 119.47 ? 155 MET B O   1 
ATOM 2532 C CB  . MET B 1 155 ? 124.734 128.599 120.056 1.00 128.32 ? 155 MET B CB  1 
ATOM 2533 C CG  . MET B 1 155 ? 125.761 127.594 120.534 1.00 135.47 ? 155 MET B CG  1 
ATOM 2534 S SD  . MET B 1 155 ? 125.280 125.879 120.467 1.00 155.37 ? 155 MET B SD  1 
ATOM 2535 C CE  . MET B 1 155 ? 126.072 125.268 121.954 1.00 143.09 ? 155 MET B CE  1 
ATOM 2536 N N   . VAL B 1 156 ? 123.177 130.527 121.561 1.00 118.27 ? 156 VAL B N   1 
ATOM 2537 C CA  . VAL B 1 156 ? 123.010 131.424 122.700 1.00 114.27 ? 156 VAL B CA  1 
ATOM 2538 C C   . VAL B 1 156 ? 121.563 131.435 123.170 1.00 113.84 ? 156 VAL B C   1 
ATOM 2539 O O   . VAL B 1 156 ? 121.290 131.445 124.375 1.00 114.50 ? 156 VAL B O   1 
ATOM 2540 C CB  . VAL B 1 156 ? 123.503 132.839 122.353 1.00 115.98 ? 156 VAL B CB  1 
ATOM 2541 C CG1 . VAL B 1 156 ? 123.712 133.639 123.621 1.00 115.24 ? 156 VAL B CG1 1 
ATOM 2542 C CG2 . VAL B 1 156 ? 124.799 132.763 121.581 1.00 120.98 ? 156 VAL B CG2 1 
ATOM 2543 N N   . THR B 1 157 ? 120.614 131.440 122.232 1.00 114.28 ? 157 THR B N   1 
ATOM 2544 C CA  . THR B 1 157 ? 119.207 131.510 122.605 1.00 113.97 ? 157 THR B CA  1 
ATOM 2545 C C   . THR B 1 157 ? 118.782 130.288 123.407 1.00 118.11 ? 157 THR B C   1 
ATOM 2546 O O   . THR B 1 157 ? 118.080 130.416 124.413 1.00 120.15 ? 157 THR B O   1 
ATOM 2547 C CB  . THR B 1 157 ? 118.343 131.661 121.355 1.00 118.62 ? 157 THR B CB  1 
ATOM 2548 O OG1 . THR B 1 157 ? 118.668 132.894 120.702 1.00 123.57 ? 157 THR B OG1 1 
ATOM 2549 C CG2 . THR B 1 157 ? 116.869 131.662 121.719 1.00 119.45 ? 157 THR B CG2 1 
ATOM 2550 N N   . GLY B 1 158 ? 119.205 129.095 122.988 1.00 119.50 ? 158 GLY B N   1 
ATOM 2551 C CA  . GLY B 1 158 ? 118.870 127.899 123.742 1.00 117.77 ? 158 GLY B CA  1 
ATOM 2552 C C   . GLY B 1 158 ? 119.525 127.871 125.109 1.00 116.74 ? 158 GLY B C   1 
ATOM 2553 O O   . GLY B 1 158 ? 118.898 127.481 126.101 1.00 118.68 ? 158 GLY B O   1 
ATOM 2554 N N   . ILE B 1 159 ? 120.793 128.286 125.185 1.00 114.35 ? 159 ILE B N   1 
ATOM 2555 C CA  . ILE B 1 159 ? 121.468 128.318 126.480 1.00 112.41 ? 159 ILE B CA  1 
ATOM 2556 C C   . ILE B 1 159 ? 120.735 129.257 127.431 1.00 115.23 ? 159 ILE B C   1 
ATOM 2557 O O   . ILE B 1 159 ? 120.475 128.920 128.593 1.00 118.42 ? 159 ILE B O   1 
ATOM 2558 C CB  . ILE B 1 159 ? 122.943 128.720 126.308 1.00 113.97 ? 159 ILE B CB  1 
ATOM 2559 C CG1 . ILE B 1 159 ? 123.792 127.492 125.987 1.00 112.72 ? 159 ILE B CG1 1 
ATOM 2560 C CG2 . ILE B 1 159 ? 123.465 129.400 127.563 1.00 116.18 ? 159 ILE B CG2 1 
ATOM 2561 C CD1 . ILE B 1 159 ? 125.090 127.821 125.294 1.00 111.44 ? 159 ILE B CD1 1 
ATOM 2562 N N   . LEU B 1 160 ? 120.370 130.444 126.940 1.00 115.74 ? 160 LEU B N   1 
ATOM 2563 C CA  . LEU B 1 160 ? 119.665 131.410 127.773 1.00 116.16 ? 160 LEU B CA  1 
ATOM 2564 C C   . LEU B 1 160 ? 118.265 130.932 128.130 1.00 118.99 ? 160 LEU B C   1 
ATOM 2565 O O   . LEU B 1 160 ? 117.785 131.209 129.231 1.00 122.22 ? 160 LEU B O   1 
ATOM 2566 C CB  . LEU B 1 160 ? 119.605 132.759 127.064 1.00 113.76 ? 160 LEU B CB  1 
ATOM 2567 C CG  . LEU B 1 160 ? 120.978 133.371 126.795 1.00 112.50 ? 160 LEU B CG  1 
ATOM 2568 C CD1 . LEU B 1 160 ? 120.840 134.761 126.219 1.00 115.63 ? 160 LEU B CD1 1 
ATOM 2569 C CD2 . LEU B 1 160 ? 121.801 133.390 128.066 1.00 112.87 ? 160 LEU B CD2 1 
ATOM 2570 N N   . LEU B 1 161 ? 117.599 130.223 127.219 1.00 118.12 ? 161 LEU B N   1 
ATOM 2571 C CA  . LEU B 1 161 ? 116.292 129.652 127.524 1.00 120.01 ? 161 LEU B CA  1 
ATOM 2572 C C   . LEU B 1 161 ? 116.390 128.669 128.681 1.00 126.75 ? 161 LEU B C   1 
ATOM 2573 O O   . LEU B 1 161 ? 115.596 128.722 129.629 1.00 130.06 ? 161 LEU B O   1 
ATOM 2574 C CB  . LEU B 1 161 ? 115.734 128.963 126.280 1.00 123.87 ? 161 LEU B CB  1 
ATOM 2575 C CG  . LEU B 1 161 ? 114.667 129.690 125.464 1.00 126.79 ? 161 LEU B CG  1 
ATOM 2576 C CD1 . LEU B 1 161 ? 113.315 129.551 126.118 1.00 128.84 ? 161 LEU B CD1 1 
ATOM 2577 C CD2 . LEU B 1 161 ? 115.034 131.149 125.330 1.00 123.70 ? 161 LEU B CD2 1 
ATOM 2578 N N   . TYR B 1 162 ? 117.375 127.771 128.624 1.00 128.11 ? 162 TYR B N   1 
ATOM 2579 C CA  . TYR B 1 162 ? 117.557 126.809 129.706 1.00 129.71 ? 162 TYR B CA  1 
ATOM 2580 C C   . TYR B 1 162 ? 117.891 127.517 131.014 1.00 130.70 ? 162 TYR B C   1 
ATOM 2581 O O   . TYR B 1 162 ? 117.346 127.178 132.074 1.00 134.62 ? 162 TYR B O   1 
ATOM 2582 C CB  . TYR B 1 162 ? 118.657 125.816 129.335 1.00 128.21 ? 162 TYR B CB  1 
ATOM 2583 C CG  . TYR B 1 162 ? 119.283 125.118 130.516 1.00 129.86 ? 162 TYR B CG  1 
ATOM 2584 C CD1 . TYR B 1 162 ? 118.542 124.251 131.305 1.00 130.38 ? 162 TYR B CD1 1 
ATOM 2585 C CD2 . TYR B 1 162 ? 120.609 125.342 130.856 1.00 131.79 ? 162 TYR B CD2 1 
ATOM 2586 C CE1 . TYR B 1 162 ? 119.109 123.611 132.385 1.00 136.00 ? 162 TYR B CE1 1 
ATOM 2587 C CE2 . TYR B 1 162 ? 121.183 124.710 131.940 1.00 136.82 ? 162 TYR B CE2 1 
ATOM 2588 C CZ  . TYR B 1 162 ? 120.428 123.846 132.700 1.00 139.69 ? 162 TYR B CZ  1 
ATOM 2589 O OH  . TYR B 1 162 ? 120.995 123.215 133.781 1.00 141.37 ? 162 TYR B OH  1 
ATOM 2590 N N   . LEU B 1 163 ? 118.777 128.515 130.954 1.00 125.26 ? 163 LEU B N   1 
ATOM 2591 C CA  . LEU B 1 163 ? 119.164 129.232 132.163 1.00 122.90 ? 163 LEU B CA  1 
ATOM 2592 C C   . LEU B 1 163 ? 117.976 129.954 132.783 1.00 127.21 ? 163 LEU B C   1 
ATOM 2593 O O   . LEU B 1 163 ? 117.789 129.918 134.003 1.00 131.98 ? 163 LEU B O   1 
ATOM 2594 C CB  . LEU B 1 163 ? 120.287 130.218 131.852 1.00 120.07 ? 163 LEU B CB  1 
ATOM 2595 C CG  . LEU B 1 163 ? 121.663 129.615 131.570 1.00 122.13 ? 163 LEU B CG  1 
ATOM 2596 C CD1 . LEU B 1 163 ? 122.743 130.675 131.691 1.00 125.55 ? 163 LEU B CD1 1 
ATOM 2597 C CD2 . LEU B 1 163 ? 121.940 128.453 132.506 1.00 125.56 ? 163 LEU B CD2 1 
ATOM 2598 N N   . ALA B 1 164 ? 117.157 130.609 131.959 1.00 126.10 ? 164 ALA B N   1 
ATOM 2599 C CA  . ALA B 1 164 ? 115.990 131.314 132.477 1.00 129.41 ? 164 ALA B CA  1 
ATOM 2600 C C   . ALA B 1 164 ? 114.970 130.344 133.054 1.00 138.29 ? 164 ALA B C   1 
ATOM 2601 O O   . ALA B 1 164 ? 114.355 130.625 134.091 1.00 140.54 ? 164 ALA B O   1 
ATOM 2602 C CB  . ALA B 1 164 ? 115.359 132.163 131.376 1.00 127.62 ? 164 ALA B CB  1 
ATOM 2603 N N   . PHE B 1 165 ? 114.773 129.196 132.397 1.00 140.15 ? 165 PHE B N   1 
ATOM 2604 C CA  . PHE B 1 165 ? 113.840 128.208 132.922 1.00 142.44 ? 165 PHE B CA  1 
ATOM 2605 C C   . PHE B 1 165 ? 114.291 127.692 134.280 1.00 142.21 ? 165 PHE B C   1 
ATOM 2606 O O   . PHE B 1 165 ? 113.463 127.501 135.177 1.00 145.53 ? 165 PHE B O   1 
ATOM 2607 C CB  . PHE B 1 165 ? 113.686 127.051 131.936 1.00 144.75 ? 165 PHE B CB  1 
ATOM 2608 C CG  . PHE B 1 165 ? 112.304 126.467 131.902 1.00 157.30 ? 165 PHE B CG  1 
ATOM 2609 C CD1 . PHE B 1 165 ? 112.116 125.100 131.787 1.00 163.22 ? 165 PHE B CD1 1 
ATOM 2610 C CD2 . PHE B 1 165 ? 111.192 127.287 131.978 1.00 156.90 ? 165 PHE B CD2 1 
ATOM 2611 C CE1 . PHE B 1 165 ? 110.843 124.562 131.752 1.00 166.63 ? 165 PHE B CE1 1 
ATOM 2612 C CE2 . PHE B 1 165 ? 109.917 126.757 131.943 1.00 159.50 ? 165 PHE B CE2 1 
ATOM 2613 C CZ  . PHE B 1 165 ? 109.742 125.392 131.830 1.00 163.54 ? 165 PHE B CZ  1 
ATOM 2614 N N   . VAL B 1 166 ? 115.592 127.466 134.452 1.00 140.26 ? 166 VAL B N   1 
ATOM 2615 C CA  . VAL B 1 166 ? 116.113 127.085 135.763 1.00 141.66 ? 166 VAL B CA  1 
ATOM 2616 C C   . VAL B 1 166 ? 115.915 128.212 136.769 1.00 141.93 ? 166 VAL B C   1 
ATOM 2617 O O   . VAL B 1 166 ? 115.506 127.983 137.913 1.00 144.10 ? 166 VAL B O   1 
ATOM 2618 C CB  . VAL B 1 166 ? 117.594 126.680 135.660 1.00 140.65 ? 166 VAL B CB  1 
ATOM 2619 C CG1 . VAL B 1 166 ? 118.211 126.573 137.044 1.00 140.67 ? 166 VAL B CG1 1 
ATOM 2620 C CG2 . VAL B 1 166 ? 117.715 125.359 134.939 1.00 140.76 ? 166 VAL B CG2 1 
ATOM 2621 N N   . ARG B 1 167 ? 116.190 129.447 136.351 1.00 140.03 ? 167 ARG B N   1 
ATOM 2622 C CA  . ARG B 1 167 ? 116.140 130.599 137.241 1.00 137.42 ? 167 ARG B CA  1 
ATOM 2623 C C   . ARG B 1 167 ? 114.737 130.827 137.784 1.00 139.74 ? 167 ARG B C   1 
ATOM 2624 O O   . ARG B 1 167 ? 114.574 131.211 138.946 1.00 140.94 ? 167 ARG B O   1 
ATOM 2625 C CB  . ARG B 1 167 ? 116.628 131.853 136.515 1.00 133.44 ? 167 ARG B CB  1 
ATOM 2626 C CG  . ARG B 1 167 ? 118.117 132.109 136.654 1.00 131.18 ? 167 ARG B CG  1 
ATOM 2627 C CD  . ARG B 1 167 ? 118.425 133.595 136.629 1.00 132.49 ? 167 ARG B CD  1 
ATOM 2628 N NE  . ARG B 1 167 ? 119.859 133.849 136.575 1.00 132.24 ? 167 ARG B NE  1 
ATOM 2629 C CZ  . ARG B 1 167 ? 120.406 135.055 136.603 1.00 131.45 ? 167 ARG B CZ  1 
ATOM 2630 N NH1 . ARG B 1 167 ? 119.665 136.146 136.686 1.00 129.37 ? 167 ARG B NH1 1 
ATOM 2631 N NH2 . ARG B 1 167 ? 121.729 135.170 136.537 1.00 131.22 ? 167 ARG B NH2 1 
ATOM 2632 N N   . LEU B 1 168 ? 113.721 130.616 136.951 1.00 141.59 ? 168 LEU B N   1 
ATOM 2633 C CA  . LEU B 1 168 ? 112.349 130.858 137.385 1.00 144.38 ? 168 LEU B CA  1 
ATOM 2634 C C   . LEU B 1 168 ? 111.926 129.924 138.513 1.00 147.99 ? 168 LEU B C   1 
ATOM 2635 O O   . LEU B 1 168 ? 111.453 130.381 139.560 1.00 150.45 ? 168 LEU B O   1 
ATOM 2636 C CB  . LEU B 1 168 ? 111.382 130.716 136.211 1.00 144.50 ? 168 LEU B CB  1 
ATOM 2637 C CG  . LEU B 1 168 ? 111.154 131.994 135.408 1.00 143.02 ? 168 LEU B CG  1 
ATOM 2638 C CD1 . LEU B 1 168 ? 110.319 131.704 134.178 1.00 141.33 ? 168 LEU B CD1 1 
ATOM 2639 C CD2 . LEU B 1 168 ? 110.487 133.039 136.277 1.00 142.84 ? 168 LEU B CD2 1 
ATOM 2640 N N   . LEU B 1 169 ? 112.099 128.617 138.316 1.00 148.79 ? 169 LEU B N   1 
ATOM 2641 C CA  . LEU B 1 169 ? 111.662 127.639 139.307 1.00 150.96 ? 169 LEU B CA  1 
ATOM 2642 C C   . LEU B 1 169 ? 112.480 127.737 140.587 1.00 151.00 ? 169 LEU B C   1 
ATOM 2643 O O   . LEU B 1 169 ? 111.919 127.842 141.683 1.00 147.84 ? 169 LEU B O   1 
ATOM 2644 C CB  . LEU B 1 169 ? 111.740 126.222 138.738 1.00 150.58 ? 169 LEU B CB  1 
ATOM 2645 C CG  . LEU B 1 169 ? 110.543 125.706 137.933 1.00 149.93 ? 169 LEU B CG  1 
ATOM 2646 C CD1 . LEU B 1 169 ? 109.847 126.781 137.094 1.00 145.75 ? 169 LEU B CD1 1 
ATOM 2647 C CD2 . LEU B 1 169 ? 110.978 124.537 137.062 1.00 144.05 ? 169 LEU B CD2 1 
ATOM 2648 N N   . HIS B 1 170 ? 113.804 127.711 140.461 1.00 151.90 ? 170 HIS B N   1 
ATOM 2649 C CA  . HIS B 1 170 ? 114.671 127.954 141.605 1.00 151.84 ? 170 HIS B CA  1 
ATOM 2650 C C   . HIS B 1 170 ? 114.844 129.452 141.797 1.00 152.50 ? 170 HIS B C   1 
ATOM 2651 O O   . HIS B 1 170 ? 115.777 130.052 141.255 1.00 154.51 ? 170 HIS B O   1 
ATOM 2652 C CB  . HIS B 1 170 ? 116.024 127.264 141.421 1.00 155.26 ? 170 HIS B CB  1 
ATOM 2653 C CG  . HIS B 1 170 ? 115.921 125.799 141.130 1.00 158.59 ? 170 HIS B CG  1 
ATOM 2654 N ND1 . HIS B 1 170 ? 115.597 125.306 139.884 1.00 158.18 ? 170 HIS B ND1 1 
ATOM 2655 C CD2 . HIS B 1 170 ? 116.102 124.719 141.926 1.00 161.26 ? 170 HIS B CD2 1 
ATOM 2656 C CE1 . HIS B 1 170 ? 115.583 123.985 139.925 1.00 160.10 ? 170 HIS B CE1 1 
ATOM 2657 N NE2 . HIS B 1 170 ? 115.885 123.604 141.153 1.00 163.65 ? 170 HIS B NE2 1 
ATOM 2658 N N   . SER B 1 171 ? 113.949 130.064 142.569 1.00 149.55 ? 171 SER B N   1 
ATOM 2659 C CA  . SER B 1 171 ? 113.980 131.507 142.763 1.00 148.95 ? 171 SER B CA  1 
ATOM 2660 C C   . SER B 1 171 ? 114.999 131.897 143.825 1.00 150.42 ? 171 SER B C   1 
ATOM 2661 O O   . SER B 1 171 ? 114.638 132.460 144.862 1.00 150.00 ? 171 SER B O   1 
ATOM 2662 C CB  . SER B 1 171 ? 112.591 132.021 143.141 1.00 145.52 ? 171 SER B CB  1 
ATOM 2663 O OG  . SER B 1 171 ? 111.626 131.622 142.183 1.00 143.91 ? 171 SER B OG  1 
ATOM 2664 N N   . ASP B 1 172 ? 116.276 131.605 143.574 1.00 151.34 ? 172 ASP B N   1 
ATOM 2665 C CA  . ASP B 1 172 ? 117.363 131.950 144.494 1.00 153.36 ? 172 ASP B CA  1 
ATOM 2666 C C   . ASP B 1 172 ? 118.519 132.452 143.630 1.00 149.96 ? 172 ASP B C   1 
ATOM 2667 O O   . ASP B 1 172 ? 119.364 131.671 143.186 1.00 147.93 ? 172 ASP B O   1 
ATOM 2668 C CB  . ASP B 1 172 ? 117.795 130.781 145.383 1.00 159.52 ? 172 ASP B CB  1 
ATOM 2669 C CG  . ASP B 1 172 ? 117.790 129.424 144.671 1.00 161.39 ? 172 ASP B CG  1 
ATOM 2670 O OD1 . ASP B 1 172 ? 118.327 128.466 145.263 1.00 170.37 ? 172 ASP B OD1 1 
ATOM 2671 O OD2 . ASP B 1 172 ? 117.300 129.294 143.533 1.00 157.68 ? 172 ASP B OD2 1 
ATOM 2672 N N   . TYR B 1 173 ? 118.544 133.760 143.393 1.00 147.63 ? 173 TYR B N   1 
ATOM 2673 C CA  . TYR B 1 173 ? 119.641 134.386 142.671 1.00 143.52 ? 173 TYR B CA  1 
ATOM 2674 C C   . TYR B 1 173 ? 119.681 135.861 143.035 1.00 142.48 ? 173 TYR B C   1 
ATOM 2675 O O   . TYR B 1 173 ? 118.643 136.489 143.255 1.00 142.80 ? 173 TYR B O   1 
ATOM 2676 C CB  . TYR B 1 173 ? 119.507 134.202 141.155 1.00 138.91 ? 173 TYR B CB  1 
ATOM 2677 C CG  . TYR B 1 173 ? 118.142 134.544 140.607 1.00 138.96 ? 173 TYR B CG  1 
ATOM 2678 C CD1 . TYR B 1 173 ? 117.149 133.580 140.514 1.00 140.16 ? 173 TYR B CD1 1 
ATOM 2679 C CD2 . TYR B 1 173 ? 117.845 135.831 140.182 1.00 136.74 ? 173 TYR B CD2 1 
ATOM 2680 C CE1 . TYR B 1 173 ? 115.900 133.888 140.013 1.00 140.44 ? 173 TYR B CE1 1 
ATOM 2681 C CE2 . TYR B 1 173 ? 116.598 136.147 139.681 1.00 134.41 ? 173 TYR B CE2 1 
ATOM 2682 C CZ  . TYR B 1 173 ? 115.630 135.172 139.600 1.00 135.24 ? 173 TYR B CZ  1 
ATOM 2683 O OH  . TYR B 1 173 ? 114.386 135.478 139.102 1.00 133.76 ? 173 TYR B OH  1 
ATOM 2684 N N   . HIS B 1 174 ? 120.891 136.404 143.099 1.00 139.42 ? 174 HIS B N   1 
ATOM 2685 C CA  . HIS B 1 174 ? 121.106 137.787 143.501 1.00 142.67 ? 174 HIS B CA  1 
ATOM 2686 C C   . HIS B 1 174 ? 121.333 138.639 142.260 1.00 145.68 ? 174 HIS B C   1 
ATOM 2687 O O   . HIS B 1 174 ? 122.236 138.358 141.465 1.00 144.30 ? 174 HIS B O   1 
ATOM 2688 C CB  . HIS B 1 174 ? 122.294 137.900 144.455 1.00 147.89 ? 174 HIS B CB  1 
ATOM 2689 C CG  . HIS B 1 174 ? 122.887 139.273 144.517 1.00 153.80 ? 174 HIS B CG  1 
ATOM 2690 N ND1 . HIS B 1 174 ? 122.234 140.340 145.096 1.00 151.08 ? 174 HIS B ND1 1 
ATOM 2691 C CD2 . HIS B 1 174 ? 124.072 139.753 144.072 1.00 155.05 ? 174 HIS B CD2 1 
ATOM 2692 C CE1 . HIS B 1 174 ? 122.992 141.418 145.005 1.00 151.44 ? 174 HIS B CE1 1 
ATOM 2693 N NE2 . HIS B 1 174 ? 124.112 141.089 144.388 1.00 154.74 ? 174 HIS B NE2 1 
ATOM 2694 N N   . ILE B 1 175 ? 120.514 139.675 142.099 1.00 147.04 ? 175 ILE B N   1 
ATOM 2695 C CA  . ILE B 1 175 ? 120.613 140.603 140.980 1.00 143.90 ? 175 ILE B CA  1 
ATOM 2696 C C   . ILE B 1 175 ? 120.640 142.018 141.536 1.00 145.10 ? 175 ILE B C   1 
ATOM 2697 O O   . ILE B 1 175 ? 119.758 142.399 142.313 1.00 150.61 ? 175 ILE B O   1 
ATOM 2698 C CB  . ILE B 1 175 ? 119.443 140.436 139.993 1.00 135.72 ? 175 ILE B CB  1 
ATOM 2699 C CG1 . ILE B 1 175 ? 119.564 139.115 139.239 1.00 133.22 ? 175 ILE B CG1 1 
ATOM 2700 C CG2 . ILE B 1 175 ? 119.394 141.598 139.020 1.00 134.03 ? 175 ILE B CG2 1 
ATOM 2701 C CD1 . ILE B 1 175 ? 118.491 138.917 138.199 1.00 127.58 ? 175 ILE B CD1 1 
ATOM 2702 N N   . GLU B 1 176 ? 121.645 142.793 141.142 1.00 142.04 ? 176 GLU B N   1 
ATOM 2703 C CA  . GLU B 1 176 ? 121.751 144.189 141.530 1.00 144.60 ? 176 GLU B CA  1 
ATOM 2704 C C   . GLU B 1 176 ? 121.529 145.065 140.307 1.00 144.46 ? 176 GLU B C   1 
ATOM 2705 O O   . GLU B 1 176 ? 122.129 144.841 139.250 1.00 143.39 ? 176 GLU B O   1 
ATOM 2706 C CB  . GLU B 1 176 ? 123.104 144.536 142.178 1.00 143.72 ? 176 GLU B CB  1 
ATOM 2707 C CG  . GLU B 1 176 ? 124.430 144.322 141.402 1.00 147.16 ? 176 GLU B CG  1 
ATOM 2708 C CD  . GLU B 1 176 ? 124.826 142.883 141.075 1.00 150.23 ? 176 GLU B CD  1 
ATOM 2709 O OE1 . GLU B 1 176 ? 123.992 142.043 140.696 1.00 146.37 ? 176 GLU B OE1 1 
ATOM 2710 O OE2 . GLU B 1 176 ? 126.028 142.588 141.224 1.00 153.65 ? 176 GLU B OE2 1 
ATOM 2711 N N   . GLY B 1 177 ? 120.662 146.068 140.458 1.00 143.91 ? 177 GLY B N   1 
ATOM 2712 C CA  . GLY B 1 177 ? 120.229 146.857 139.320 1.00 136.02 ? 177 GLY B CA  1 
ATOM 2713 C C   . GLY B 1 177 ? 121.231 147.872 138.824 1.00 135.92 ? 177 GLY B C   1 
ATOM 2714 O O   . GLY B 1 177 ? 121.049 148.411 137.729 1.00 136.63 ? 177 GLY B O   1 
ATOM 2715 N N   . GLY B 1 178 ? 122.282 148.147 139.591 1.00 133.68 ? 178 GLY B N   1 
ATOM 2716 C CA  . GLY B 1 178 ? 123.257 149.135 139.175 1.00 135.13 ? 178 GLY B CA  1 
ATOM 2717 C C   . GLY B 1 178 ? 123.964 148.749 137.893 1.00 136.43 ? 178 GLY B C   1 
ATOM 2718 O O   . GLY B 1 178 ? 123.751 149.373 136.844 1.00 136.99 ? 178 GLY B O   1 
ATOM 2719 N N   . ALA B 1 179 ? 124.780 147.694 137.971 1.00 133.45 ? 179 ALA B N   1 
ATOM 2720 C CA  . ALA B 1 179 ? 125.502 147.218 136.798 1.00 136.96 ? 179 ALA B CA  1 
ATOM 2721 C C   . ALA B 1 179 ? 124.551 146.954 135.641 1.00 137.27 ? 179 ALA B C   1 
ATOM 2722 O O   . ALA B 1 179 ? 124.878 147.239 134.484 1.00 137.81 ? 179 ALA B O   1 
ATOM 2723 C CB  . ALA B 1 179 ? 126.292 145.957 137.146 1.00 136.69 ? 179 ALA B CB  1 
ATOM 2724 N N   . MET B 1 180 ? 123.364 146.418 135.941 1.00 134.06 ? 180 MET B N   1 
ATOM 2725 C CA  . MET B 1 180 ? 122.335 146.236 134.922 1.00 130.05 ? 180 MET B CA  1 
ATOM 2726 C C   . MET B 1 180 ? 122.034 147.540 134.199 1.00 132.70 ? 180 MET B C   1 
ATOM 2727 O O   . MET B 1 180 ? 121.998 147.588 132.966 1.00 135.54 ? 180 MET B O   1 
ATOM 2728 C CB  . MET B 1 180 ? 121.061 145.687 135.562 1.00 129.44 ? 180 MET B CB  1 
ATOM 2729 C CG  . MET B 1 180 ? 120.994 144.184 135.658 1.00 133.66 ? 180 MET B CG  1 
ATOM 2730 S SD  . MET B 1 180 ? 119.870 143.527 134.415 1.00 134.82 ? 180 MET B SD  1 
ATOM 2731 C CE  . MET B 1 180 ? 118.309 143.639 135.277 1.00 120.18 ? 180 MET B CE  1 
ATOM 2732 N N   . LEU B 1 181 ? 121.813 148.612 134.959 1.00 131.55 ? 181 LEU B N   1 
ATOM 2733 C CA  . LEU B 1 181 ? 121.446 149.888 134.359 1.00 130.42 ? 181 LEU B CA  1 
ATOM 2734 C C   . LEU B 1 181 ? 122.575 150.439 133.498 1.00 135.56 ? 181 LEU B C   1 
ATOM 2735 O O   . LEU B 1 181 ? 122.347 150.879 132.364 1.00 137.10 ? 181 LEU B O   1 
ATOM 2736 C CB  . LEU B 1 181 ? 121.063 150.882 135.453 1.00 126.92 ? 181 LEU B CB  1 
ATOM 2737 C CG  . LEU B 1 181 ? 120.058 151.956 135.048 1.00 122.03 ? 181 LEU B CG  1 
ATOM 2738 C CD1 . LEU B 1 181 ? 118.740 151.304 134.696 1.00 117.97 ? 181 LEU B CD1 1 
ATOM 2739 C CD2 . LEU B 1 181 ? 119.877 152.961 136.168 1.00 124.38 ? 181 LEU B CD2 1 
ATOM 2740 N N   . LEU B 1 182 ? 123.807 150.422 134.019 1.00 132.62 ? 182 LEU B N   1 
ATOM 2741 C CA  . LEU B 1 182 ? 124.916 150.942 133.215 1.00 130.71 ? 182 LEU B CA  1 
ATOM 2742 C C   . LEU B 1 182 ? 125.133 150.129 131.943 1.00 132.83 ? 182 LEU B C   1 
ATOM 2743 O O   . LEU B 1 182 ? 125.334 150.703 130.864 1.00 136.84 ? 182 LEU B O   1 
ATOM 2744 C CB  . LEU B 1 182 ? 126.221 151.052 134.012 1.00 128.60 ? 182 LEU B CB  1 
ATOM 2745 C CG  . LEU B 1 182 ? 126.403 151.932 135.260 1.00 132.55 ? 182 LEU B CG  1 
ATOM 2746 C CD1 . LEU B 1 182 ? 126.059 153.377 134.917 1.00 131.13 ? 182 LEU B CD1 1 
ATOM 2747 C CD2 . LEU B 1 182 ? 125.664 151.503 136.493 1.00 131.85 ? 182 LEU B CD2 1 
ATOM 2748 N N   . THR B 1 183 ? 125.080 148.798 132.027 1.00 129.19 ? 183 THR B N   1 
ATOM 2749 C CA  . THR B 1 183 ? 125.331 148.026 130.814 1.00 133.24 ? 183 THR B CA  1 
ATOM 2750 C C   . THR B 1 183 ? 124.162 148.112 129.837 1.00 137.28 ? 183 THR B C   1 
ATOM 2751 O O   . THR B 1 183 ? 124.372 148.048 128.622 1.00 143.52 ? 183 THR B O   1 
ATOM 2752 C CB  . THR B 1 183 ? 125.661 146.572 131.153 1.00 134.20 ? 183 THR B CB  1 
ATOM 2753 O OG1 . THR B 1 183 ? 125.982 145.864 129.950 1.00 141.48 ? 183 THR B OG1 1 
ATOM 2754 C CG2 . THR B 1 183 ? 124.502 145.895 131.824 1.00 132.92 ? 183 THR B CG2 1 
ATOM 2755 N N   . ALA B 1 184 ? 122.934 148.297 130.330 1.00 135.15 ? 184 ALA B N   1 
ATOM 2756 C CA  . ALA B 1 184 ? 121.810 148.517 129.426 1.00 132.18 ? 184 ALA B CA  1 
ATOM 2757 C C   . ALA B 1 184 ? 121.929 149.860 128.720 1.00 134.16 ? 184 ALA B C   1 
ATOM 2758 O O   . ALA B 1 184 ? 121.586 149.981 127.537 1.00 137.64 ? 184 ALA B O   1 
ATOM 2759 C CB  . ALA B 1 184 ? 120.492 148.425 130.190 1.00 129.37 ? 184 ALA B CB  1 
ATOM 2760 N N   . SER B 1 185 ? 122.402 150.886 129.430 1.00 133.74 ? 185 SER B N   1 
ATOM 2761 C CA  . SER B 1 185 ? 122.679 152.158 128.772 1.00 138.49 ? 185 SER B CA  1 
ATOM 2762 C C   . SER B 1 185 ? 123.756 151.993 127.709 1.00 141.99 ? 185 SER B C   1 
ATOM 2763 O O   . SER B 1 185 ? 123.641 152.535 126.601 1.00 144.62 ? 185 SER B O   1 
ATOM 2764 C CB  . SER B 1 185 ? 123.097 153.204 129.804 1.00 139.10 ? 185 SER B CB  1 
ATOM 2765 O OG  . SER B 1 185 ? 122.189 153.237 130.890 1.00 139.02 ? 185 SER B OG  1 
ATOM 2766 N N   . ILE B 1 186 ? 124.810 151.241 128.027 1.00 139.87 ? 186 ILE B N   1 
ATOM 2767 C CA  . ILE B 1 186 ? 125.850 150.980 127.039 1.00 140.16 ? 186 ILE B CA  1 
ATOM 2768 C C   . ILE B 1 186 ? 125.251 150.305 125.813 1.00 142.79 ? 186 ILE B C   1 
ATOM 2769 O O   . ILE B 1 186 ? 125.564 150.672 124.673 1.00 147.08 ? 186 ILE B O   1 
ATOM 2770 C CB  . ILE B 1 186 ? 126.981 150.140 127.668 1.00 142.43 ? 186 ILE B CB  1 
ATOM 2771 C CG1 . ILE B 1 186 ? 128.122 151.040 128.146 1.00 145.75 ? 186 ILE B CG1 1 
ATOM 2772 C CG2 . ILE B 1 186 ? 127.513 149.112 126.682 1.00 147.59 ? 186 ILE B CG2 1 
ATOM 2773 C CD1 . ILE B 1 186 ? 127.695 152.139 129.096 1.00 142.43 ? 186 ILE B CD1 1 
ATOM 2774 N N   . ALA B 1 187 ? 124.359 149.336 126.025 1.00 140.52 ? 187 ALA B N   1 
ATOM 2775 C CA  . ALA B 1 187 ? 123.705 148.648 124.920 1.00 140.01 ? 187 ALA B CA  1 
ATOM 2776 C C   . ALA B 1 187 ? 122.850 149.582 124.075 1.00 142.74 ? 187 ALA B C   1 
ATOM 2777 O O   . ALA B 1 187 ? 122.861 149.476 122.844 1.00 146.48 ? 187 ALA B O   1 
ATOM 2778 C CB  . ALA B 1 187 ? 122.843 147.503 125.449 1.00 137.62 ? 187 ALA B CB  1 
ATOM 2779 N N   . VAL B 1 188 ? 122.095 150.485 124.703 1.00 139.65 ? 188 VAL B N   1 
ATOM 2780 C CA  . VAL B 1 188 ? 121.227 151.345 123.902 1.00 141.93 ? 188 VAL B CA  1 
ATOM 2781 C C   . VAL B 1 188 ? 122.051 152.350 123.101 1.00 149.94 ? 188 VAL B C   1 
ATOM 2782 O O   . VAL B 1 188 ? 121.722 152.640 121.944 1.00 153.34 ? 188 VAL B O   1 
ATOM 2783 C CB  . VAL B 1 188 ? 120.151 152.034 124.767 1.00 140.62 ? 188 VAL B CB  1 
ATOM 2784 C CG1 . VAL B 1 188 ? 120.763 152.917 125.825 1.00 141.23 ? 188 VAL B CG1 1 
ATOM 2785 C CG2 . VAL B 1 188 ? 119.197 152.829 123.890 1.00 142.98 ? 188 VAL B CG2 1 
ATOM 2786 N N   . CYS B 1 189 ? 123.139 152.887 123.670 1.00 150.78 ? 189 CYS B N   1 
ATOM 2787 C CA  . CYS B 1 189 ? 123.996 153.743 122.846 1.00 151.98 ? 189 CYS B CA  1 
ATOM 2788 C C   . CYS B 1 189 ? 124.686 152.959 121.734 1.00 151.71 ? 189 CYS B C   1 
ATOM 2789 O O   . CYS B 1 189 ? 124.870 153.491 120.632 1.00 153.63 ? 189 CYS B O   1 
ATOM 2790 C CB  . CYS B 1 189 ? 125.033 154.494 123.684 1.00 152.55 ? 189 CYS B CB  1 
ATOM 2791 S SG  . CYS B 1 189 ? 124.543 154.965 125.350 1.00 157.96 ? 189 CYS B SG  1 
ATOM 2792 N N   . ALA B 1 190 ? 125.069 151.706 121.990 1.00 149.91 ? 190 ALA B N   1 
ATOM 2793 C CA  . ALA B 1 190 ? 125.627 150.886 120.919 1.00 149.86 ? 190 ALA B CA  1 
ATOM 2794 C C   . ALA B 1 190 ? 124.617 150.696 119.796 1.00 153.30 ? 190 ALA B C   1 
ATOM 2795 O O   . ALA B 1 190 ? 124.967 150.776 118.612 1.00 160.79 ? 190 ALA B O   1 
ATOM 2796 C CB  . ALA B 1 190 ? 126.070 149.531 121.466 1.00 148.81 ? 190 ALA B CB  1 
ATOM 2797 N N   . ASN B 1 191 ? 123.360 150.442 120.153 1.00 150.69 ? 191 ASN B N   1 
ATOM 2798 C CA  . ASN B 1 191 ? 122.323 150.292 119.141 1.00 152.31 ? 191 ASN B CA  1 
ATOM 2799 C C   . ASN B 1 191 ? 122.091 151.588 118.379 1.00 157.76 ? 191 ASN B C   1 
ATOM 2800 O O   . ASN B 1 191 ? 121.846 151.566 117.169 1.00 161.51 ? 191 ASN B O   1 
ATOM 2801 C CB  . ASN B 1 191 ? 121.029 149.808 119.780 1.00 150.08 ? 191 ASN B CB  1 
ATOM 2802 C CG  . ASN B 1 191 ? 120.760 148.360 119.491 1.00 150.75 ? 191 ASN B CG  1 
ATOM 2803 O OD1 . ASN B 1 191 ? 121.157 147.492 120.264 1.00 149.25 ? 191 ASN B OD1 1 
ATOM 2804 N ND2 . ASN B 1 191 ? 120.087 148.083 118.381 1.00 151.95 ? 191 ASN B ND2 1 
ATOM 2805 N N   . LEU B 1 192 ? 122.143 152.727 119.071 1.00 157.64 ? 192 LEU B N   1 
ATOM 2806 C CA  . LEU B 1 192 ? 121.998 154.004 118.380 1.00 161.04 ? 192 LEU B CA  1 
ATOM 2807 C C   . LEU B 1 192 ? 123.133 154.223 117.388 1.00 165.67 ? 192 LEU B C   1 
ATOM 2808 O O   . LEU B 1 192 ? 122.908 154.695 116.267 1.00 169.97 ? 192 LEU B O   1 
ATOM 2809 C CB  . LEU B 1 192 ? 121.938 155.147 119.392 1.00 158.99 ? 192 LEU B CB  1 
ATOM 2810 C CG  . LEU B 1 192 ? 120.650 155.232 120.212 1.00 156.65 ? 192 LEU B CG  1 
ATOM 2811 C CD1 . LEU B 1 192 ? 120.638 156.496 121.051 1.00 157.59 ? 192 LEU B CD1 1 
ATOM 2812 C CD2 . LEU B 1 192 ? 119.434 155.176 119.303 1.00 154.96 ? 192 LEU B CD2 1 
ATOM 2813 N N   . LEU B 1 193 ? 124.360 153.879 117.782 1.00 164.80 ? 193 LEU B N   1 
ATOM 2814 C CA  . LEU B 1 193 ? 125.489 153.991 116.864 1.00 167.27 ? 193 LEU B CA  1 
ATOM 2815 C C   . LEU B 1 193 ? 125.312 153.070 115.662 1.00 170.21 ? 193 LEU B C   1 
ATOM 2816 O O   . LEU B 1 193 ? 125.595 153.464 114.524 1.00 173.34 ? 193 LEU B O   1 
ATOM 2817 C CB  . LEU B 1 193 ? 126.793 153.696 117.611 1.00 168.49 ? 193 LEU B CB  1 
ATOM 2818 C CG  . LEU B 1 193 ? 128.124 153.406 116.909 1.00 171.33 ? 193 LEU B CG  1 
ATOM 2819 C CD1 . LEU B 1 193 ? 129.247 153.677 117.888 1.00 171.04 ? 193 LEU B CD1 1 
ATOM 2820 C CD2 . LEU B 1 193 ? 128.229 151.965 116.421 1.00 166.65 ? 193 LEU B CD2 1 
ATOM 2821 N N   . MET B 1 194 ? 124.851 151.840 115.894 1.00 168.29 ? 194 MET B N   1 
ATOM 2822 C CA  . MET B 1 194 ? 124.611 150.920 114.786 1.00 167.58 ? 194 MET B CA  1 
ATOM 2823 C C   . MET B 1 194 ? 123.529 151.443 113.850 1.00 172.98 ? 194 MET B C   1 
ATOM 2824 O O   . MET B 1 194 ? 123.647 151.313 112.626 1.00 178.50 ? 194 MET B O   1 
ATOM 2825 C CB  . MET B 1 194 ? 124.228 149.540 115.321 1.00 161.21 ? 194 MET B CB  1 
ATOM 2826 C CG  . MET B 1 194 ? 124.923 148.384 114.623 1.00 154.12 ? 194 MET B CG  1 
ATOM 2827 S SD  . MET B 1 194 ? 126.517 148.002 115.371 1.00 144.97 ? 194 MET B SD  1 
ATOM 2828 C CE  . MET B 1 194 ? 127.241 146.940 114.124 1.00 142.74 ? 194 MET B CE  1 
ATOM 2829 N N   . ALA B 1 195 ? 122.467 152.028 114.405 1.00 171.24 ? 195 ALA B N   1 
ATOM 2830 C CA  . ALA B 1 195 ? 121.405 152.597 113.583 1.00 174.59 ? 195 ALA B CA  1 
ATOM 2831 C C   . ALA B 1 195 ? 121.924 153.767 112.758 1.00 182.55 ? 195 ALA B C   1 
ATOM 2832 O O   . ALA B 1 195 ? 121.561 153.932 111.589 1.00 185.87 ? 195 ALA B O   1 
ATOM 2833 C CB  . ALA B 1 195 ? 120.236 153.030 114.468 1.00 169.89 ? 195 ALA B CB  1 
ATOM 2834 N N   . PHE B 1 196 ? 122.778 154.600 113.359 1.00 183.11 ? 196 PHE B N   1 
ATOM 2835 C CA  . PHE B 1 196 ? 123.381 155.699 112.613 1.00 185.06 ? 196 PHE B CA  1 
ATOM 2836 C C   . PHE B 1 196 ? 124.233 155.150 111.475 1.00 185.55 ? 196 PHE B C   1 
ATOM 2837 O O   . PHE B 1 196 ? 124.163 155.648 110.346 1.00 185.90 ? 196 PHE B O   1 
ATOM 2838 C CB  . PHE B 1 196 ? 124.200 156.576 113.577 1.00 183.96 ? 196 PHE B CB  1 
ATOM 2839 C CG  . PHE B 1 196 ? 125.402 157.267 112.964 1.00 188.55 ? 196 PHE B CG  1 
ATOM 2840 C CD1 . PHE B 1 196 ? 125.323 157.939 111.748 1.00 189.52 ? 196 PHE B CD1 1 
ATOM 2841 C CD2 . PHE B 1 196 ? 126.624 157.232 113.615 1.00 187.60 ? 196 PHE B CD2 1 
ATOM 2842 C CE1 . PHE B 1 196 ? 126.431 158.558 111.204 1.00 188.34 ? 196 PHE B CE1 1 
ATOM 2843 C CE2 . PHE B 1 196 ? 127.737 157.850 113.075 1.00 188.63 ? 196 PHE B CE2 1 
ATOM 2844 C CZ  . PHE B 1 196 ? 127.640 158.514 111.868 1.00 189.43 ? 196 PHE B CZ  1 
ATOM 2845 N N   . VAL B 1 197 ? 125.016 154.101 111.746 1.00 184.03 ? 197 VAL B N   1 
ATOM 2846 C CA  . VAL B 1 197 ? 125.850 153.499 110.706 1.00 180.60 ? 197 VAL B CA  1 
ATOM 2847 C C   . VAL B 1 197 ? 124.982 152.979 109.567 1.00 183.25 ? 197 VAL B C   1 
ATOM 2848 O O   . VAL B 1 197 ? 125.300 153.161 108.385 1.00 181.70 ? 197 VAL B O   1 
ATOM 2849 C CB  . VAL B 1 197 ? 126.730 152.386 111.302 1.00 174.84 ? 197 VAL B CB  1 
ATOM 2850 C CG1 . VAL B 1 197 ? 127.150 151.399 110.222 1.00 170.59 ? 197 VAL B CG1 1 
ATOM 2851 C CG2 . VAL B 1 197 ? 127.949 152.985 111.986 1.00 173.16 ? 197 VAL B CG2 1 
ATOM 2852 N N   . LEU B 1 198 ? 123.868 152.328 109.907 1.00 186.00 ? 198 LEU B N   1 
ATOM 2853 C CA  . LEU B 1 198 ? 122.937 151.865 108.882 1.00 187.10 ? 198 LEU B CA  1 
ATOM 2854 C C   . LEU B 1 198 ? 122.391 153.038 108.075 1.00 190.05 ? 198 LEU B C   1 
ATOM 2855 O O   . LEU B 1 198 ? 122.281 152.962 106.846 1.00 188.87 ? 198 LEU B O   1 
ATOM 2856 C CB  . LEU B 1 198 ? 121.798 151.072 109.529 1.00 186.61 ? 198 LEU B CB  1 
ATOM 2857 C CG  . LEU B 1 198 ? 120.743 150.384 108.651 1.00 184.72 ? 198 LEU B CG  1 
ATOM 2858 C CD1 . LEU B 1 198 ? 119.563 151.301 108.337 1.00 181.22 ? 198 LEU B CD1 1 
ATOM 2859 C CD2 . LEU B 1 198 ? 121.365 149.839 107.371 1.00 181.47 ? 198 LEU B CD2 1 
ATOM 2860 N N   . HIS B 1 199 ? 122.045 154.127 108.750 1.00 192.16 ? 199 HIS B N   1 
ATOM 2861 C CA  . HIS B 1 199 ? 121.577 155.336 108.085 1.00 192.92 ? 199 HIS B CA  1 
ATOM 2862 C C   . HIS B 1 199 ? 122.725 156.045 107.374 1.00 189.75 ? 199 HIS B C   1 
ATOM 2863 O O   . HIS B 1 199 ? 122.645 156.335 106.181 1.00 184.09 ? 199 HIS B O   1 
ATOM 2864 C CB  . HIS B 1 199 ? 120.918 156.279 109.094 1.00 193.28 ? 199 HIS B CB  1 
ATOM 2865 C CG  . HIS B 1 199 ? 120.766 157.684 108.599 1.00 196.31 ? 199 HIS B CG  1 
ATOM 2866 N ND1 . HIS B 1 199 ? 121.695 158.669 108.858 1.00 195.35 ? 199 HIS B ND1 1 
ATOM 2867 C CD2 . HIS B 1 199 ? 119.792 158.270 107.863 1.00 194.31 ? 199 HIS B CD2 1 
ATOM 2868 C CE1 . HIS B 1 199 ? 121.301 159.800 108.302 1.00 193.25 ? 199 HIS B CE1 1 
ATOM 2869 N NE2 . HIS B 1 199 ? 120.149 159.585 107.692 1.00 192.65 ? 199 HIS B NE2 1 
ATOM 2870 N N   . VAL B 1 237 ? 113.132 148.093 109.950 1.00 172.62 ? 237 VAL B N   1 
ATOM 2871 C CA  . VAL B 1 237 ? 113.404 146.688 109.686 1.00 174.12 ? 237 VAL B CA  1 
ATOM 2872 C C   . VAL B 1 237 ? 113.697 146.029 111.042 1.00 174.20 ? 237 VAL B C   1 
ATOM 2873 O O   . VAL B 1 237 ? 113.413 146.615 112.095 1.00 173.73 ? 237 VAL B O   1 
ATOM 2874 C CB  . VAL B 1 237 ? 114.569 146.531 108.662 1.00 170.23 ? 237 VAL B CB  1 
ATOM 2875 C CG1 . VAL B 1 237 ? 115.897 147.007 109.252 1.00 166.53 ? 237 VAL B CG1 1 
ATOM 2876 C CG2 . VAL B 1 237 ? 114.645 145.116 108.066 1.00 167.91 ? 237 VAL B CG2 1 
ATOM 2877 N N   . HIS B 1 238 ? 114.248 144.816 111.038 1.00 172.74 ? 238 HIS B N   1 
ATOM 2878 C CA  . HIS B 1 238 ? 114.541 144.223 112.335 1.00 168.61 ? 238 HIS B CA  1 
ATOM 2879 C C   . HIS B 1 238 ? 115.665 144.946 113.055 1.00 169.20 ? 238 HIS B C   1 
ATOM 2880 O O   . HIS B 1 238 ? 115.806 144.716 114.244 1.00 166.81 ? 238 HIS B O   1 
ATOM 2881 C CB  . HIS B 1 238 ? 114.847 142.728 112.179 1.00 164.25 ? 238 HIS B CB  1 
ATOM 2882 C CG  . HIS B 1 238 ? 116.295 142.404 111.962 1.00 170.07 ? 238 HIS B CG  1 
ATOM 2883 N ND1 . HIS B 1 238 ? 117.255 142.563 112.939 1.00 167.97 ? 238 HIS B ND1 1 
ATOM 2884 C CD2 . HIS B 1 238 ? 116.943 141.919 110.877 1.00 174.90 ? 238 HIS B CD2 1 
ATOM 2885 C CE1 . HIS B 1 238 ? 118.431 142.194 112.465 1.00 168.36 ? 238 HIS B CE1 1 
ATOM 2886 N NE2 . HIS B 1 238 ? 118.270 141.799 111.215 1.00 176.69 ? 238 HIS B NE2 1 
ATOM 2887 N N   . VAL B 1 239 ? 116.449 145.823 112.423 1.00 169.78 ? 239 VAL B N   1 
ATOM 2888 C CA  . VAL B 1 239 ? 117.369 146.663 113.184 1.00 165.96 ? 239 VAL B CA  1 
ATOM 2889 C C   . VAL B 1 239 ? 116.605 147.591 114.123 1.00 163.54 ? 239 VAL B C   1 
ATOM 2890 O O   . VAL B 1 239 ? 116.926 147.692 115.313 1.00 160.21 ? 239 VAL B O   1 
ATOM 2891 C CB  . VAL B 1 239 ? 118.265 147.506 112.258 1.00 172.61 ? 239 VAL B CB  1 
ATOM 2892 C CG1 . VAL B 1 239 ? 119.123 148.462 113.072 1.00 167.65 ? 239 VAL B CG1 1 
ATOM 2893 C CG2 . VAL B 1 239 ? 119.133 146.605 111.393 1.00 173.38 ? 239 VAL B CG2 1 
ATOM 2894 N N   . LEU B 1 240 ? 115.576 148.266 113.608 1.00 165.24 ? 240 LEU B N   1 
ATOM 2895 C CA  . LEU B 1 240 ? 114.724 149.079 114.469 1.00 164.97 ? 240 LEU B CA  1 
ATOM 2896 C C   . LEU B 1 240 ? 113.956 148.202 115.450 1.00 164.70 ? 240 LEU B C   1 
ATOM 2897 O O   . LEU B 1 240 ? 113.708 148.600 116.596 1.00 163.18 ? 240 LEU B O   1 
ATOM 2898 C CB  . LEU B 1 240 ? 113.779 149.926 113.610 1.00 166.20 ? 240 LEU B CB  1 
ATOM 2899 C CG  . LEU B 1 240 ? 112.650 150.787 114.197 1.00 167.55 ? 240 LEU B CG  1 
ATOM 2900 C CD1 . LEU B 1 240 ? 111.415 149.982 114.599 1.00 168.48 ? 240 LEU B CD1 1 
ATOM 2901 C CD2 . LEU B 1 240 ? 113.163 151.609 115.373 1.00 162.50 ? 240 LEU B CD2 1 
ATOM 2902 N N   . GLY B 1 241 ? 113.569 147.006 115.018 1.00 165.19 ? 241 GLY B N   1 
ATOM 2903 C CA  . GLY B 1 241 ? 112.941 146.061 115.922 1.00 162.10 ? 241 GLY B CA  1 
ATOM 2904 C C   . GLY B 1 241 ? 113.823 145.733 117.111 1.00 157.69 ? 241 GLY B C   1 
ATOM 2905 O O   . GLY B 1 241 ? 113.353 145.654 118.250 1.00 151.68 ? 241 GLY B O   1 
ATOM 2906 N N   . ASP B 1 242 ? 115.114 145.548 116.846 1.00 158.27 ? 242 ASP B N   1 
ATOM 2907 C CA  . ASP B 1 242 ? 116.108 145.252 117.867 1.00 152.09 ? 242 ASP B CA  1 
ATOM 2908 C C   . ASP B 1 242 ? 116.301 146.476 118.752 1.00 148.44 ? 242 ASP B C   1 
ATOM 2909 O O   . ASP B 1 242 ? 116.502 146.345 119.962 1.00 148.02 ? 242 ASP B O   1 
ATOM 2910 C CB  . ASP B 1 242 ? 117.422 144.820 117.203 1.00 151.56 ? 242 ASP B CB  1 
ATOM 2911 C CG  . ASP B 1 242 ? 118.596 144.770 118.168 1.00 149.13 ? 242 ASP B CG  1 
ATOM 2912 O OD1 . ASP B 1 242 ? 118.957 145.794 118.773 1.00 149.75 ? 242 ASP B OD1 1 
ATOM 2913 O OD2 . ASP B 1 242 ? 119.185 143.683 118.309 1.00 145.54 ? 242 ASP B OD2 1 
ATOM 2914 N N   . LEU B 1 243 ? 116.269 147.664 118.149 1.00 147.03 ? 243 LEU B N   1 
ATOM 2915 C CA  . LEU B 1 243 ? 116.332 148.914 118.899 1.00 144.85 ? 243 LEU B CA  1 
ATOM 2916 C C   . LEU B 1 243 ? 115.220 148.927 119.940 1.00 143.30 ? 243 LEU B C   1 
ATOM 2917 O O   . LEU B 1 243 ? 115.436 149.289 121.104 1.00 143.58 ? 243 LEU B O   1 
ATOM 2918 C CB  . LEU B 1 243 ? 116.206 150.110 117.949 1.00 149.12 ? 243 LEU B CB  1 
ATOM 2919 C CG  . LEU B 1 243 ? 116.703 151.512 118.325 1.00 147.79 ? 243 LEU B CG  1 
ATOM 2920 C CD1 . LEU B 1 243 ? 115.931 152.118 119.488 1.00 145.99 ? 243 LEU B CD1 1 
ATOM 2921 C CD2 . LEU B 1 243 ? 118.187 151.499 118.624 1.00 147.43 ? 243 LEU B CD2 1 
ATOM 2922 N N   . LEU B 1 244 ? 114.024 148.524 119.514 1.00 144.37 ? 244 LEU B N   1 
ATOM 2923 C CA  . LEU B 1 244 ? 112.908 148.412 120.447 1.00 145.28 ? 244 LEU B CA  1 
ATOM 2924 C C   . LEU B 1 244 ? 113.212 147.392 121.539 1.00 144.47 ? 244 LEU B C   1 
ATOM 2925 O O   . LEU B 1 244 ? 112.880 147.605 122.711 1.00 142.66 ? 244 LEU B O   1 
ATOM 2926 C CB  . LEU B 1 244 ? 111.630 148.047 119.688 1.00 147.68 ? 244 LEU B CB  1 
ATOM 2927 C CG  . LEU B 1 244 ? 110.271 148.129 120.396 1.00 149.48 ? 244 LEU B CG  1 
ATOM 2928 C CD1 . LEU B 1 244 ? 109.984 146.921 121.285 1.00 143.38 ? 244 LEU B CD1 1 
ATOM 2929 C CD2 . LEU B 1 244 ? 110.181 149.418 121.199 1.00 148.52 ? 244 LEU B CD2 1 
ATOM 2930 N N   . GLN B 1 245 ? 113.848 146.276 121.174 1.00 143.89 ? 245 GLN B N   1 
ATOM 2931 C CA  . GLN B 1 245 ? 114.215 145.272 122.168 1.00 137.33 ? 245 GLN B CA  1 
ATOM 2932 C C   . GLN B 1 245 ? 115.217 145.823 123.176 1.00 132.72 ? 245 GLN B C   1 
ATOM 2933 O O   . GLN B 1 245 ? 115.116 145.547 124.378 1.00 129.71 ? 245 GLN B O   1 
ATOM 2934 C CB  . GLN B 1 245 ? 114.781 144.036 121.474 1.00 135.46 ? 245 GLN B CB  1 
ATOM 2935 C CG  . GLN B 1 245 ? 115.242 142.960 122.430 1.00 129.78 ? 245 GLN B CG  1 
ATOM 2936 C CD  . GLN B 1 245 ? 116.748 142.904 122.548 1.00 133.93 ? 245 GLN B CD  1 
ATOM 2937 O OE1 . GLN B 1 245 ? 117.431 143.914 122.389 1.00 137.32 ? 245 GLN B OE1 1 
ATOM 2938 N NE2 . GLN B 1 245 ? 117.276 141.722 122.836 1.00 129.86 ? 245 GLN B NE2 1 
ATOM 2939 N N   . SER B 1 246 ? 116.204 146.586 122.704 1.00 133.55 ? 246 SER B N   1 
ATOM 2940 C CA  . SER B 1 246 ? 117.170 147.190 123.615 1.00 125.19 ? 246 SER B CA  1 
ATOM 2941 C C   . SER B 1 246 ? 116.490 148.174 124.554 1.00 126.23 ? 246 SER B C   1 
ATOM 2942 O O   . SER B 1 246 ? 116.824 148.244 125.743 1.00 126.91 ? 246 SER B O   1 
ATOM 2943 C CB  . SER B 1 246 ? 118.277 147.882 122.827 1.00 130.99 ? 246 SER B CB  1 
ATOM 2944 O OG  . SER B 1 246 ? 118.804 148.972 123.562 1.00 134.45 ? 246 SER B OG  1 
ATOM 2945 N N   . PHE B 1 247 ? 115.533 148.947 124.035 1.00 127.76 ? 247 PHE B N   1 
ATOM 2946 C CA  . PHE B 1 247 ? 114.766 149.837 124.901 1.00 127.44 ? 247 PHE B CA  1 
ATOM 2947 C C   . PHE B 1 247 ? 113.973 149.048 125.936 1.00 125.40 ? 247 PHE B C   1 
ATOM 2948 O O   . PHE B 1 247 ? 113.846 149.474 127.089 1.00 126.49 ? 247 PHE B O   1 
ATOM 2949 C CB  . PHE B 1 247 ? 113.841 150.720 124.069 1.00 130.52 ? 247 PHE B CB  1 
ATOM 2950 C CG  . PHE B 1 247 ? 114.409 152.075 123.779 1.00 136.49 ? 247 PHE B CG  1 
ATOM 2951 C CD1 . PHE B 1 247 ? 115.186 152.726 124.721 1.00 133.73 ? 247 PHE B CD1 1 
ATOM 2952 C CD2 . PHE B 1 247 ? 114.167 152.700 122.569 1.00 144.43 ? 247 PHE B CD2 1 
ATOM 2953 C CE1 . PHE B 1 247 ? 115.712 153.974 124.462 1.00 139.88 ? 247 PHE B CE1 1 
ATOM 2954 C CE2 . PHE B 1 247 ? 114.690 153.950 122.304 1.00 148.07 ? 247 PHE B CE2 1 
ATOM 2955 C CZ  . PHE B 1 247 ? 115.464 154.587 123.253 1.00 146.61 ? 247 PHE B CZ  1 
ATOM 2956 N N   . GLY B 1 248 ? 113.431 147.897 125.542 1.00 123.80 ? 248 GLY B N   1 
ATOM 2957 C CA  . GLY B 1 248 ? 112.740 147.054 126.505 1.00 126.48 ? 248 GLY B CA  1 
ATOM 2958 C C   . GLY B 1 248 ? 113.656 146.548 127.603 1.00 123.42 ? 248 GLY B C   1 
ATOM 2959 O O   . GLY B 1 248 ? 113.287 146.540 128.781 1.00 120.03 ? 248 GLY B O   1 
ATOM 2960 N N   . VAL B 1 249 ? 114.862 146.114 127.232 1.00 125.43 ? 249 VAL B N   1 
ATOM 2961 C CA  . VAL B 1 249 ? 115.827 145.662 128.233 1.00 116.55 ? 249 VAL B CA  1 
ATOM 2962 C C   . VAL B 1 249 ? 116.186 146.803 129.173 1.00 113.60 ? 249 VAL B C   1 
ATOM 2963 O O   . VAL B 1 249 ? 116.298 146.614 130.389 1.00 115.30 ? 249 VAL B O   1 
ATOM 2964 C CB  . VAL B 1 249 ? 117.084 145.078 127.563 1.00 118.91 ? 249 VAL B CB  1 
ATOM 2965 C CG1 . VAL B 1 249 ? 118.069 144.619 128.620 1.00 113.45 ? 249 VAL B CG1 1 
ATOM 2966 C CG2 . VAL B 1 249 ? 116.722 143.928 126.654 1.00 123.33 ? 249 VAL B CG2 1 
ATOM 2967 N N   . LEU B 1 250 ? 116.385 148.001 128.623 1.00 114.67 ? 250 LEU B N   1 
ATOM 2968 C CA  . LEU B 1 250 ? 116.689 149.162 129.453 1.00 111.64 ? 250 LEU B CA  1 
ATOM 2969 C C   . LEU B 1 250 ? 115.550 149.457 130.425 1.00 115.47 ? 250 LEU B C   1 
ATOM 2970 O O   . LEU B 1 250 ? 115.787 149.752 131.605 1.00 119.61 ? 250 LEU B O   1 
ATOM 2971 C CB  . LEU B 1 250 ? 116.996 150.356 128.545 1.00 111.60 ? 250 LEU B CB  1 
ATOM 2972 C CG  . LEU B 1 250 ? 117.231 151.793 129.014 1.00 111.45 ? 250 LEU B CG  1 
ATOM 2973 C CD1 . LEU B 1 250 ? 115.927 152.535 129.236 1.00 113.76 ? 250 LEU B CD1 1 
ATOM 2974 C CD2 . LEU B 1 250 ? 118.089 151.816 130.262 1.00 119.49 ? 250 LEU B CD2 1 
ATOM 2975 N N   . ALA B 1 251 ? 114.306 149.361 129.952 1.00 115.79 ? 251 ALA B N   1 
ATOM 2976 C CA  . ALA B 1 251 ? 113.162 149.568 130.835 1.00 116.65 ? 251 ALA B CA  1 
ATOM 2977 C C   . ALA B 1 251 ? 113.131 148.526 131.945 1.00 121.17 ? 251 ALA B C   1 
ATOM 2978 O O   . ALA B 1 251 ? 112.843 148.849 133.104 1.00 124.18 ? 251 ALA B O   1 
ATOM 2979 C CB  . ALA B 1 251 ? 111.865 149.533 130.030 1.00 114.87 ? 251 ALA B CB  1 
ATOM 2980 N N   . ALA B 1 252 ? 113.432 147.270 131.610 1.00 120.24 ? 252 ALA B N   1 
ATOM 2981 C CA  . ALA B 1 252 ? 113.497 146.233 132.636 1.00 117.86 ? 252 ALA B CA  1 
ATOM 2982 C C   . ALA B 1 252 ? 114.604 146.523 133.642 1.00 118.70 ? 252 ALA B C   1 
ATOM 2983 O O   . ALA B 1 252 ? 114.466 146.220 134.832 1.00 120.51 ? 252 ALA B O   1 
ATOM 2984 C CB  . ALA B 1 252 ? 113.702 144.863 131.991 1.00 115.88 ? 252 ALA B CB  1 
ATOM 2985 N N   . SER B 1 253 ? 115.716 147.096 133.179 1.00 118.99 ? 253 SER B N   1 
ATOM 2986 C CA  . SER B 1 253 ? 116.789 147.462 134.098 1.00 112.14 ? 253 SER B CA  1 
ATOM 2987 C C   . SER B 1 253 ? 116.339 148.537 135.076 1.00 115.23 ? 253 SER B C   1 
ATOM 2988 O O   . SER B 1 253 ? 116.627 148.449 136.275 1.00 120.52 ? 253 SER B O   1 
ATOM 2989 C CB  . SER B 1 253 ? 118.021 147.926 133.326 1.00 119.06 ? 253 SER B CB  1 
ATOM 2990 O OG  . SER B 1 253 ? 118.224 147.140 132.169 1.00 128.63 ? 253 SER B OG  1 
ATOM 2991 N N   . ILE B 1 254 ? 115.633 149.563 134.590 1.00 117.32 ? 254 ILE B N   1 
ATOM 2992 C CA  . ILE B 1 254 ? 115.081 150.547 135.525 1.00 116.46 ? 254 ILE B CA  1 
ATOM 2993 C C   . ILE B 1 254 ? 114.114 149.880 136.494 1.00 120.07 ? 254 ILE B C   1 
ATOM 2994 O O   . ILE B 1 254 ? 114.114 150.179 137.694 1.00 124.21 ? 254 ILE B O   1 
ATOM 2995 C CB  . ILE B 1 254 ? 114.413 151.733 134.802 1.00 113.73 ? 254 ILE B CB  1 
ATOM 2996 C CG1 . ILE B 1 254 ? 115.447 152.640 134.141 1.00 113.50 ? 254 ILE B CG1 1 
ATOM 2997 C CG2 . ILE B 1 254 ? 113.565 152.542 135.767 1.00 118.95 ? 254 ILE B CG2 1 
ATOM 2998 C CD1 . ILE B 1 254 ? 115.521 152.521 132.679 1.00 111.88 ? 254 ILE B CD1 1 
ATOM 2999 N N   . LEU B 1 255 ? 113.282 148.965 135.995 1.00 120.95 ? 255 LEU B N   1 
ATOM 3000 C CA  . LEU B 1 255 ? 112.309 148.315 136.868 1.00 126.27 ? 255 LEU B CA  1 
ATOM 3001 C C   . LEU B 1 255 ? 113.004 147.533 137.978 1.00 128.52 ? 255 LEU B C   1 
ATOM 3002 O O   . LEU B 1 255 ? 112.590 147.591 139.141 1.00 129.93 ? 255 LEU B O   1 
ATOM 3003 C CB  . LEU B 1 255 ? 111.396 147.409 136.037 1.00 128.97 ? 255 LEU B CB  1 
ATOM 3004 C CG  . LEU B 1 255 ? 110.113 146.782 136.607 1.00 132.21 ? 255 LEU B CG  1 
ATOM 3005 C CD1 . LEU B 1 255 ? 110.333 145.795 137.750 1.00 129.84 ? 255 LEU B CD1 1 
ATOM 3006 C CD2 . LEU B 1 255 ? 109.160 147.886 137.040 1.00 133.88 ? 255 LEU B CD2 1 
ATOM 3007 N N   . ILE B 1 256 ? 114.063 146.799 137.638 1.00 128.34 ? 256 ILE B N   1 
ATOM 3008 C CA  . ILE B 1 256 ? 114.773 146.005 138.637 1.00 125.09 ? 256 ILE B CA  1 
ATOM 3009 C C   . ILE B 1 256 ? 115.501 146.913 139.621 1.00 124.15 ? 256 ILE B C   1 
ATOM 3010 O O   . ILE B 1 256 ? 115.423 146.724 140.840 1.00 127.30 ? 256 ILE B O   1 
ATOM 3011 C CB  . ILE B 1 256 ? 115.741 145.023 137.952 1.00 122.95 ? 256 ILE B CB  1 
ATOM 3012 C CG1 . ILE B 1 256 ? 115.037 143.704 137.645 1.00 126.90 ? 256 ILE B CG1 1 
ATOM 3013 C CG2 . ILE B 1 256 ? 116.957 144.765 138.825 1.00 120.89 ? 256 ILE B CG2 1 
ATOM 3014 C CD1 . ILE B 1 256 ? 114.645 142.927 138.872 1.00 130.79 ? 256 ILE B CD1 1 
ATOM 3015 N N   . TYR B 1 257 ? 116.213 147.918 139.106 1.00 121.55 ? 257 TYR B N   1 
ATOM 3016 C CA  . TYR B 1 257 ? 117.034 148.760 139.969 1.00 123.06 ? 257 TYR B CA  1 
ATOM 3017 C C   . TYR B 1 257 ? 116.184 149.578 140.932 1.00 126.65 ? 257 TYR B C   1 
ATOM 3018 O O   . TYR B 1 257 ? 116.517 149.693 142.116 1.00 130.02 ? 257 TYR B O   1 
ATOM 3019 C CB  . TYR B 1 257 ? 117.910 149.675 139.116 1.00 123.71 ? 257 TYR B CB  1 
ATOM 3020 C CG  . TYR B 1 257 ? 118.499 150.843 139.868 1.00 123.30 ? 257 TYR B CG  1 
ATOM 3021 C CD1 . TYR B 1 257 ? 119.391 150.645 140.910 1.00 126.62 ? 257 TYR B CD1 1 
ATOM 3022 C CD2 . TYR B 1 257 ? 118.166 152.145 139.531 1.00 126.08 ? 257 TYR B CD2 1 
ATOM 3023 C CE1 . TYR B 1 257 ? 119.933 151.713 141.597 1.00 129.19 ? 257 TYR B CE1 1 
ATOM 3024 C CE2 . TYR B 1 257 ? 118.702 153.218 140.212 1.00 130.52 ? 257 TYR B CE2 1 
ATOM 3025 C CZ  . TYR B 1 257 ? 119.585 152.997 141.243 1.00 131.81 ? 257 TYR B CZ  1 
ATOM 3026 O OH  . TYR B 1 257 ? 120.120 154.066 141.923 1.00 138.05 ? 257 TYR B OH  1 
ATOM 3027 N N   . PHE B 1 258 ? 115.087 150.157 140.443 1.00 126.62 ? 258 PHE B N   1 
ATOM 3028 C CA  . PHE B 1 258 ? 114.272 151.021 141.290 1.00 130.17 ? 258 PHE B CA  1 
ATOM 3029 C C   . PHE B 1 258 ? 113.566 150.229 142.382 1.00 132.17 ? 258 PHE B C   1 
ATOM 3030 O O   . PHE B 1 258 ? 113.490 150.677 143.531 1.00 132.43 ? 258 PHE B O   1 
ATOM 3031 C CB  . PHE B 1 258 ? 113.258 151.779 140.436 1.00 134.18 ? 258 PHE B CB  1 
ATOM 3032 C CG  . PHE B 1 258 ? 113.712 153.148 140.034 1.00 135.28 ? 258 PHE B CG  1 
ATOM 3033 C CD1 . PHE B 1 258 ? 115.015 153.554 140.266 1.00 133.01 ? 258 PHE B CD1 1 
ATOM 3034 C CD2 . PHE B 1 258 ? 112.838 154.029 139.422 1.00 137.73 ? 258 PHE B CD2 1 
ATOM 3035 C CE1 . PHE B 1 258 ? 115.437 154.814 139.896 1.00 135.20 ? 258 PHE B CE1 1 
ATOM 3036 C CE2 . PHE B 1 258 ? 113.254 155.291 139.050 1.00 141.84 ? 258 PHE B CE2 1 
ATOM 3037 C CZ  . PHE B 1 258 ? 114.556 155.684 139.287 1.00 142.25 ? 258 PHE B CZ  1 
ATOM 3038 N N   . LYS B 1 259 ? 113.048 149.048 142.046 1.00 131.81 ? 259 LYS B N   1 
ATOM 3039 C CA  . LYS B 1 259 ? 112.297 148.210 142.978 1.00 135.98 ? 259 LYS B CA  1 
ATOM 3040 C C   . LYS B 1 259 ? 112.992 146.859 143.076 1.00 138.37 ? 259 LYS B C   1 
ATOM 3041 O O   . LYS B 1 259 ? 112.661 145.923 142.332 1.00 141.36 ? 259 LYS B O   1 
ATOM 3042 C CB  . LYS B 1 259 ? 110.846 148.052 142.531 1.00 138.40 ? 259 LYS B CB  1 
ATOM 3043 C CG  . LYS B 1 259 ? 109.922 149.138 143.044 1.00 140.48 ? 259 LYS B CG  1 
ATOM 3044 C CD  . LYS B 1 259 ? 110.086 149.332 144.542 1.00 140.29 ? 259 LYS B CD  1 
ATOM 3045 C CE  . LYS B 1 259 ? 108.761 149.670 145.202 1.00 135.63 ? 259 LYS B CE  1 
ATOM 3046 N NZ  . LYS B 1 259 ? 108.512 151.137 145.227 1.00 128.46 ? 259 LYS B NZ  1 
ATOM 3047 N N   . PRO B 1 260 ? 113.959 146.711 143.984 1.00 139.62 ? 260 PRO B N   1 
ATOM 3048 C CA  . PRO B 1 260 ? 114.669 145.427 144.092 1.00 139.42 ? 260 PRO B CA  1 
ATOM 3049 C C   . PRO B 1 260 ? 113.785 144.280 144.537 1.00 137.54 ? 260 PRO B C   1 
ATOM 3050 O O   . PRO B 1 260 ? 114.161 143.120 144.328 1.00 134.53 ? 260 PRO B O   1 
ATOM 3051 C CB  . PRO B 1 260 ? 115.771 145.709 145.121 1.00 141.34 ? 260 PRO B CB  1 
ATOM 3052 C CG  . PRO B 1 260 ? 115.354 146.938 145.844 1.00 140.17 ? 260 PRO B CG  1 
ATOM 3053 C CD  . PRO B 1 260 ? 114.353 147.680 145.019 1.00 136.44 ? 260 PRO B CD  1 
ATOM 3054 N N   . GLN B 1 261 ? 112.627 144.560 145.141 1.00 138.72 ? 261 GLN B N   1 
ATOM 3055 C CA  . GLN B 1 261 ? 111.757 143.483 145.599 1.00 139.90 ? 261 GLN B CA  1 
ATOM 3056 C C   . GLN B 1 261 ? 111.274 142.639 144.428 1.00 140.36 ? 261 GLN B C   1 
ATOM 3057 O O   . GLN B 1 261 ? 111.138 141.416 144.549 1.00 138.79 ? 261 GLN B O   1 
ATOM 3058 C CB  . GLN B 1 261 ? 110.585 144.058 146.399 1.00 140.80 ? 261 GLN B CB  1 
ATOM 3059 C CG  . GLN B 1 261 ? 109.736 145.088 145.669 1.00 140.74 ? 261 GLN B CG  1 
ATOM 3060 C CD  . GLN B 1 261 ? 108.485 144.492 145.050 1.00 145.27 ? 261 GLN B CD  1 
ATOM 3061 O OE1 . GLN B 1 261 ? 108.455 143.319 144.683 1.00 147.31 ? 261 GLN B OE1 1 
ATOM 3062 N NE2 . GLN B 1 261 ? 107.442 145.304 144.933 1.00 145.82 ? 261 GLN B NE2 1 
ATOM 3063 N N   . TYR B 1 262 ? 111.007 143.270 143.288 1.00 140.33 ? 262 TYR B N   1 
ATOM 3064 C CA  . TYR B 1 262 ? 110.773 142.518 142.065 1.00 139.05 ? 262 TYR B CA  1 
ATOM 3065 C C   . TYR B 1 262 ? 112.063 141.828 141.645 1.00 137.99 ? 262 TYR B C   1 
ATOM 3066 O O   . TYR B 1 262 ? 113.137 142.436 141.662 1.00 137.79 ? 262 TYR B O   1 
ATOM 3067 C CB  . TYR B 1 262 ? 110.273 143.439 140.955 1.00 140.74 ? 262 TYR B CB  1 
ATOM 3068 C CG  . TYR B 1 262 ? 108.938 144.081 141.250 1.00 145.97 ? 262 TYR B CG  1 
ATOM 3069 C CD1 . TYR B 1 262 ? 108.757 145.449 141.103 1.00 144.60 ? 262 TYR B CD1 1 
ATOM 3070 C CD2 . TYR B 1 262 ? 107.856 143.318 141.665 1.00 146.10 ? 262 TYR B CD2 1 
ATOM 3071 C CE1 . TYR B 1 262 ? 107.538 146.040 141.369 1.00 145.39 ? 262 TYR B CE1 1 
ATOM 3072 C CE2 . TYR B 1 262 ? 106.633 143.900 141.935 1.00 147.81 ? 262 TYR B CE2 1 
ATOM 3073 C CZ  . TYR B 1 262 ? 106.480 145.261 141.784 1.00 148.71 ? 262 TYR B CZ  1 
ATOM 3074 O OH  . TYR B 1 262 ? 105.264 145.847 142.049 1.00 148.35 ? 262 TYR B OH  1 
ATOM 3075 N N   . LYS B 1 263 ? 111.960 140.553 141.288 1.00 136.11 ? 263 LYS B N   1 
ATOM 3076 C CA  . LYS B 1 263 ? 113.129 139.756 140.944 1.00 134.30 ? 263 LYS B CA  1 
ATOM 3077 C C   . LYS B 1 263 ? 112.960 138.917 139.690 1.00 129.64 ? 263 LYS B C   1 
ATOM 3078 O O   . LYS B 1 263 ? 113.972 138.549 139.082 1.00 130.79 ? 263 LYS B O   1 
ATOM 3079 C CB  . LYS B 1 263 ? 113.502 138.834 142.115 1.00 140.34 ? 263 LYS B CB  1 
ATOM 3080 C CG  . LYS B 1 263 ? 114.985 138.549 142.259 1.00 135.88 ? 263 LYS B CG  1 
ATOM 3081 C CD  . LYS B 1 263 ? 115.246 137.722 143.510 1.00 134.86 ? 263 LYS B CD  1 
ATOM 3082 C CE  . LYS B 1 263 ? 114.842 136.270 143.320 1.00 134.82 ? 263 LYS B CE  1 
ATOM 3083 N NZ  . LYS B 1 263 ? 115.969 135.438 142.827 1.00 138.28 ? 263 LYS B NZ  1 
ATOM 3084 N N   . ALA B 1 264 ? 111.735 138.611 139.277 1.00 127.08 ? 264 ALA B N   1 
ATOM 3085 C CA  . ALA B 1 264 ? 111.485 137.788 138.104 1.00 129.21 ? 264 ALA B CA  1 
ATOM 3086 C C   . ALA B 1 264 ? 111.415 138.603 136.822 1.00 130.63 ? 264 ALA B C   1 
ATOM 3087 O O   . ALA B 1 264 ? 111.034 138.064 135.779 1.00 128.73 ? 264 ALA B O   1 
ATOM 3088 C CB  . ALA B 1 264 ? 110.191 136.993 138.286 1.00 136.46 ? 264 ALA B CB  1 
ATOM 3089 N N   . ALA B 1 265 ? 111.759 139.891 136.881 1.00 130.01 ? 265 ALA B N   1 
ATOM 3090 C CA  . ALA B 1 265 ? 111.750 140.714 135.678 1.00 126.53 ? 265 ALA B CA  1 
ATOM 3091 C C   . ALA B 1 265 ? 112.787 140.233 134.673 1.00 122.50 ? 265 ALA B C   1 
ATOM 3092 O O   . ALA B 1 265 ? 112.554 140.275 133.462 1.00 124.64 ? 265 ALA B O   1 
ATOM 3093 C CB  . ALA B 1 265 ? 111.994 142.177 136.041 1.00 126.21 ? 265 ALA B CB  1 
ATOM 3094 N N   . ASP B 1 266 ? 113.939 139.779 135.156 1.00 118.66 ? 266 ASP B N   1 
ATOM 3095 C CA  . ASP B 1 266 ? 115.002 139.347 134.251 1.00 118.21 ? 266 ASP B CA  1 
ATOM 3096 C C   . ASP B 1 266 ? 114.618 138.150 133.386 1.00 122.77 ? 266 ASP B C   1 
ATOM 3097 O O   . ASP B 1 266 ? 114.711 138.259 132.149 1.00 128.54 ? 266 ASP B O   1 
ATOM 3098 C CB  . ASP B 1 266 ? 116.266 139.073 135.068 1.00 118.75 ? 266 ASP B CB  1 
ATOM 3099 C CG  . ASP B 1 266 ? 117.508 139.046 134.223 1.00 128.17 ? 266 ASP B CG  1 
ATOM 3100 O OD1 . ASP B 1 266 ? 117.613 139.862 133.284 1.00 129.97 ? 266 ASP B OD1 1 
ATOM 3101 O OD2 . ASP B 1 266 ? 118.384 138.209 134.509 1.00 132.67 ? 266 ASP B OD2 1 
ATOM 3102 N N   . PRO B 1 267 ? 114.187 137.006 133.934 1.00 119.98 ? 267 PRO B N   1 
ATOM 3103 C CA  . PRO B 1 267 ? 113.909 135.855 133.060 1.00 123.76 ? 267 PRO B CA  1 
ATOM 3104 C C   . PRO B 1 267 ? 112.788 136.091 132.063 1.00 128.03 ? 267 PRO B C   1 
ATOM 3105 O O   . PRO B 1 267 ? 112.862 135.575 130.940 1.00 131.00 ? 267 PRO B O   1 
ATOM 3106 C CB  . PRO B 1 267 ? 113.553 134.740 134.052 1.00 125.45 ? 267 PRO B CB  1 
ATOM 3107 C CG  . PRO B 1 267 ? 113.076 135.451 135.250 1.00 125.88 ? 267 PRO B CG  1 
ATOM 3108 C CD  . PRO B 1 267 ? 113.921 136.677 135.345 1.00 123.02 ? 267 PRO B CD  1 
ATOM 3109 N N   . ILE B 1 268 ? 111.750 136.847 132.424 1.00 123.75 ? 268 ILE B N   1 
ATOM 3110 C CA  . ILE B 1 268 ? 110.666 137.068 131.474 1.00 123.62 ? 268 ILE B CA  1 
ATOM 3111 C C   . ILE B 1 268 ? 111.156 137.894 130.291 1.00 122.32 ? 268 ILE B C   1 
ATOM 3112 O O   . ILE B 1 268 ? 110.807 137.615 129.137 1.00 123.50 ? 268 ILE B O   1 
ATOM 3113 C CB  . ILE B 1 268 ? 109.448 137.707 132.168 1.00 127.06 ? 268 ILE B CB  1 
ATOM 3114 C CG1 . ILE B 1 268 ? 109.798 139.062 132.780 1.00 122.94 ? 268 ILE B CG1 1 
ATOM 3115 C CG2 . ILE B 1 268 ? 108.905 136.778 133.239 1.00 127.79 ? 268 ILE B CG2 1 
ATOM 3116 C CD1 . ILE B 1 268 ? 108.675 140.073 132.706 1.00 114.39 ? 268 ILE B CD1 1 
ATOM 3117 N N   . SER B 1 269 ? 111.982 138.912 130.551 1.00 119.35 ? 269 SER B N   1 
ATOM 3118 C CA  . SER B 1 269 ? 112.583 139.661 129.455 1.00 116.73 ? 269 SER B CA  1 
ATOM 3119 C C   . SER B 1 269 ? 113.470 138.764 128.608 1.00 118.66 ? 269 SER B C   1 
ATOM 3120 O O   . SER B 1 269 ? 113.463 138.862 127.376 1.00 123.35 ? 269 SER B O   1 
ATOM 3121 C CB  . SER B 1 269 ? 113.376 140.851 129.987 1.00 112.05 ? 269 SER B CB  1 
ATOM 3122 O OG  . SER B 1 269 ? 112.735 141.433 131.102 1.00 119.47 ? 269 SER B OG  1 
ATOM 3123 N N   . THR B 1 270 ? 114.240 137.882 129.249 1.00 116.59 ? 270 THR B N   1 
ATOM 3124 C CA  . THR B 1 270 ? 115.018 136.910 128.489 1.00 118.55 ? 270 THR B CA  1 
ATOM 3125 C C   . THR B 1 270 ? 114.128 136.136 127.526 1.00 122.86 ? 270 THR B C   1 
ATOM 3126 O O   . THR B 1 270 ? 114.439 136.010 126.336 1.00 125.22 ? 270 THR B O   1 
ATOM 3127 C CB  . THR B 1 270 ? 115.738 135.949 129.434 1.00 117.71 ? 270 THR B CB  1 
ATOM 3128 O OG1 . THR B 1 270 ? 116.221 136.667 130.573 1.00 123.11 ? 270 THR B OG1 1 
ATOM 3129 C CG2 . THR B 1 270 ? 116.903 135.285 128.729 1.00 115.57 ? 270 THR B CG2 1 
ATOM 3130 N N   . PHE B 1 271 ? 112.996 135.639 128.024 1.00 122.55 ? 271 PHE B N   1 
ATOM 3131 C CA  . PHE B 1 271 ? 112.099 134.843 127.190 1.00 124.31 ? 271 PHE B CA  1 
ATOM 3132 C C   . PHE B 1 271 ? 111.571 135.654 126.011 1.00 123.27 ? 271 PHE B C   1 
ATOM 3133 O O   . PHE B 1 271 ? 111.689 135.238 124.849 1.00 127.46 ? 271 PHE B O   1 
ATOM 3134 C CB  . PHE B 1 271 ? 110.939 134.313 128.032 1.00 123.06 ? 271 PHE B CB  1 
ATOM 3135 C CG  . PHE B 1 271 ? 111.281 133.096 128.839 1.00 127.24 ? 271 PHE B CG  1 
ATOM 3136 C CD1 . PHE B 1 271 ? 111.214 133.128 130.219 1.00 130.67 ? 271 PHE B CD1 1 
ATOM 3137 C CD2 . PHE B 1 271 ? 111.659 131.919 128.222 1.00 129.58 ? 271 PHE B CD2 1 
ATOM 3138 C CE1 . PHE B 1 271 ? 111.529 132.014 130.968 1.00 134.31 ? 271 PHE B CE1 1 
ATOM 3139 C CE2 . PHE B 1 271 ? 111.970 130.800 128.970 1.00 133.52 ? 271 PHE B CE2 1 
ATOM 3140 C CZ  . PHE B 1 271 ? 111.905 130.849 130.342 1.00 135.81 ? 271 PHE B CZ  1 
ATOM 3141 N N   . LEU B 1 272 ? 110.993 136.826 126.291 1.00 117.21 ? 272 LEU B N   1 
ATOM 3142 C CA  . LEU B 1 272 ? 110.378 137.600 125.215 1.00 117.20 ? 272 LEU B CA  1 
ATOM 3143 C C   . LEU B 1 272 ? 111.406 138.034 124.181 1.00 121.67 ? 272 LEU B C   1 
ATOM 3144 O O   . LEU B 1 272 ? 111.147 137.968 122.974 1.00 127.80 ? 272 LEU B O   1 
ATOM 3145 C CB  . LEU B 1 272 ? 109.631 138.816 125.764 1.00 115.48 ? 272 LEU B CB  1 
ATOM 3146 C CG  . LEU B 1 272 ? 108.916 138.721 127.107 1.00 116.27 ? 272 LEU B CG  1 
ATOM 3147 C CD1 . LEU B 1 272 ? 108.695 140.102 127.694 1.00 112.36 ? 272 LEU B CD1 1 
ATOM 3148 C CD2 . LEU B 1 272 ? 107.598 137.987 126.956 1.00 119.33 ? 272 LEU B CD2 1 
ATOM 3149 N N   . PHE B 1 273 ? 112.584 138.468 124.623 1.00 118.81 ? 273 PHE B N   1 
ATOM 3150 C CA  . PHE B 1 273 ? 113.550 138.991 123.668 1.00 116.30 ? 273 PHE B CA  1 
ATOM 3151 C C   . PHE B 1 273 ? 114.269 137.886 122.905 1.00 119.18 ? 273 PHE B C   1 
ATOM 3152 O O   . PHE B 1 273 ? 114.632 138.086 121.741 1.00 126.43 ? 273 PHE B O   1 
ATOM 3153 C CB  . PHE B 1 273 ? 114.519 139.920 124.391 1.00 117.33 ? 273 PHE B CB  1 
ATOM 3154 C CG  . PHE B 1 273 ? 113.826 141.053 125.093 1.00 122.20 ? 273 PHE B CG  1 
ATOM 3155 C CD1 . PHE B 1 273 ? 112.734 141.670 124.507 1.00 123.27 ? 273 PHE B CD1 1 
ATOM 3156 C CD2 . PHE B 1 273 ? 114.245 141.490 126.334 1.00 123.65 ? 273 PHE B CD2 1 
ATOM 3157 C CE1 . PHE B 1 273 ? 112.080 142.704 125.142 1.00 124.14 ? 273 PHE B CE1 1 
ATOM 3158 C CE2 . PHE B 1 273 ? 113.590 142.525 126.975 1.00 122.30 ? 273 PHE B CE2 1 
ATOM 3159 C CZ  . PHE B 1 273 ? 112.510 143.133 126.377 1.00 122.73 ? 273 PHE B CZ  1 
ATOM 3160 N N   . SER B 1 274 ? 114.447 136.706 123.503 1.00 117.42 ? 274 SER B N   1 
ATOM 3161 C CA  . SER B 1 274 ? 114.929 135.573 122.722 1.00 124.20 ? 274 SER B CA  1 
ATOM 3162 C C   . SER B 1 274 ? 113.912 135.170 121.660 1.00 123.93 ? 274 SER B C   1 
ATOM 3163 O O   . SER B 1 274 ? 114.285 134.845 120.523 1.00 124.95 ? 274 SER B O   1 
ATOM 3164 C CB  . SER B 1 274 ? 115.244 134.400 123.645 1.00 123.20 ? 274 SER B CB  1 
ATOM 3165 O OG  . SER B 1 274 ? 114.081 133.974 124.328 1.00 122.25 ? 274 SER B OG  1 
ATOM 3166 N N   . ILE B 1 275 ? 112.623 135.188 122.009 1.00 120.57 ? 275 ILE B N   1 
ATOM 3167 C CA  . ILE B 1 275 ? 111.591 134.904 121.013 1.00 121.52 ? 275 ILE B CA  1 
ATOM 3168 C C   . ILE B 1 275 ? 111.633 135.941 119.897 1.00 124.16 ? 275 ILE B C   1 
ATOM 3169 O O   . ILE B 1 275 ? 111.491 135.609 118.712 1.00 128.87 ? 275 ILE B O   1 
ATOM 3170 C CB  . ILE B 1 275 ? 110.203 134.831 121.681 1.00 122.80 ? 275 ILE B CB  1 
ATOM 3171 C CG1 . ILE B 1 275 ? 109.875 133.400 122.125 1.00 125.07 ? 275 ILE B CG1 1 
ATOM 3172 C CG2 . ILE B 1 275 ? 109.119 135.355 120.750 1.00 121.98 ? 275 ILE B CG2 1 
ATOM 3173 C CD1 . ILE B 1 275 ? 110.998 132.661 122.821 1.00 124.44 ? 275 ILE B CD1 1 
ATOM 3174 N N   . CYS B 1 276 ? 111.831 137.212 120.256 1.00 122.15 ? 276 CYS B N   1 
ATOM 3175 C CA  . CYS B 1 276 ? 111.940 138.259 119.246 1.00 121.33 ? 276 CYS B CA  1 
ATOM 3176 C C   . CYS B 1 276 ? 113.128 138.017 118.325 1.00 121.70 ? 276 CYS B C   1 
ATOM 3177 O O   . CYS B 1 276 ? 113.026 138.207 117.109 1.00 125.92 ? 276 CYS B O   1 
ATOM 3178 C CB  . CYS B 1 276 ? 112.060 139.629 119.910 1.00 122.64 ? 276 CYS B CB  1 
ATOM 3179 S SG  . CYS B 1 276 ? 112.861 140.873 118.871 1.00 122.97 ? 276 CYS B SG  1 
ATOM 3180 N N   . ALA B 1 277 ? 114.266 137.607 118.889 1.00 119.64 ? 277 ALA B N   1 
ATOM 3181 C CA  . ALA B 1 277 ? 115.436 137.311 118.068 1.00 122.76 ? 277 ALA B CA  1 
ATOM 3182 C C   . ALA B 1 277 ? 115.147 136.184 117.086 1.00 127.10 ? 277 ALA B C   1 
ATOM 3183 O O   . ALA B 1 277 ? 115.468 136.280 115.893 1.00 130.72 ? 277 ALA B O   1 
ATOM 3184 C CB  . ALA B 1 277 ? 116.622 136.949 118.959 1.00 119.25 ? 277 ALA B CB  1 
ATOM 3185 N N   . LEU B 1 278 ? 114.541 135.099 117.575 1.00 125.13 ? 278 LEU B N   1 
ATOM 3186 C CA  . LEU B 1 278 ? 114.243 133.974 116.694 1.00 125.69 ? 278 LEU B CA  1 
ATOM 3187 C C   . LEU B 1 278 ? 113.287 134.385 115.581 1.00 126.22 ? 278 LEU B C   1 
ATOM 3188 O O   . LEU B 1 278 ? 113.493 134.037 114.410 1.00 126.58 ? 278 LEU B O   1 
ATOM 3189 C CB  . LEU B 1 278 ? 113.667 132.814 117.502 1.00 123.66 ? 278 LEU B CB  1 
ATOM 3190 C CG  . LEU B 1 278 ? 114.605 132.241 118.565 1.00 121.43 ? 278 LEU B CG  1 
ATOM 3191 C CD1 . LEU B 1 278 ? 114.036 130.965 119.154 1.00 124.83 ? 278 LEU B CD1 1 
ATOM 3192 C CD2 . LEU B 1 278 ? 115.981 131.994 117.978 1.00 123.86 ? 278 LEU B CD2 1 
ATOM 3193 N N   . GLY B 1 279 ? 112.245 135.143 115.922 1.00 127.54 ? 279 GLY B N   1 
ATOM 3194 C CA  . GLY B 1 279 ? 111.314 135.596 114.903 1.00 127.82 ? 279 GLY B CA  1 
ATOM 3195 C C   . GLY B 1 279 ? 111.960 136.529 113.898 1.00 129.64 ? 279 GLY B C   1 
ATOM 3196 O O   . GLY B 1 279 ? 111.619 136.513 112.713 1.00 133.25 ? 279 GLY B O   1 
ATOM 3197 N N   . SER B 1 280 ? 112.902 137.356 114.356 1.00 128.41 ? 280 SER B N   1 
ATOM 3198 C CA  . SER B 1 280 ? 113.547 138.306 113.459 1.00 129.32 ? 280 SER B CA  1 
ATOM 3199 C C   . SER B 1 280 ? 114.482 137.606 112.484 1.00 125.79 ? 280 SER B C   1 
ATOM 3200 O O   . SER B 1 280 ? 114.576 138.003 111.317 1.00 129.73 ? 280 SER B O   1 
ATOM 3201 C CB  . SER B 1 280 ? 114.305 139.358 114.266 1.00 133.78 ? 280 SER B CB  1 
ATOM 3202 O OG  . SER B 1 280 ? 115.572 138.873 114.668 1.00 135.16 ? 280 SER B OG  1 
ATOM 3203 N N   . THR B 1 281 ? 115.190 136.574 112.936 1.00 122.92 ? 281 THR B N   1 
ATOM 3204 C CA  . THR B 1 281 ? 116.129 135.877 112.063 1.00 124.74 ? 281 THR B CA  1 
ATOM 3205 C C   . THR B 1 281 ? 115.551 134.635 111.397 1.00 123.67 ? 281 THR B C   1 
ATOM 3206 O O   . THR B 1 281 ? 116.292 133.919 110.718 1.00 121.18 ? 281 THR B O   1 
ATOM 3207 C CB  . THR B 1 281 ? 117.400 135.507 112.826 1.00 125.51 ? 281 THR B CB  1 
ATOM 3208 O OG1 . THR B 1 281 ? 117.242 134.221 113.441 1.00 119.16 ? 281 THR B OG1 1 
ATOM 3209 C CG2 . THR B 1 281 ? 117.722 136.564 113.859 1.00 131.10 ? 281 THR B CG2 1 
ATOM 3210 N N   . ALA B 1 282 ? 114.263 134.352 111.577 1.00 124.46 ? 282 ALA B N   1 
ATOM 3211 C CA  . ALA B 1 282 ? 113.634 133.303 110.774 1.00 118.37 ? 282 ALA B CA  1 
ATOM 3212 C C   . ALA B 1 282 ? 113.720 133.553 109.269 1.00 116.23 ? 282 ALA B C   1 
ATOM 3213 O O   . ALA B 1 282 ? 114.076 132.614 108.535 1.00 119.71 ? 282 ALA B O   1 
ATOM 3214 C CB  . ALA B 1 282 ? 112.182 133.116 111.222 1.00 119.37 ? 282 ALA B CB  1 
ATOM 3215 N N   . PRO B 1 283 ? 113.393 134.742 108.737 1.00 115.98 ? 283 PRO B N   1 
ATOM 3216 C CA  . PRO B 1 283 ? 113.449 134.911 107.271 1.00 117.73 ? 283 PRO B CA  1 
ATOM 3217 C C   . PRO B 1 283 ? 114.831 134.709 106.676 1.00 116.32 ? 283 PRO B C   1 
ATOM 3218 O O   . PRO B 1 283 ? 114.953 134.178 105.563 1.00 117.07 ? 283 PRO B O   1 
ATOM 3219 C CB  . PRO B 1 283 ? 112.952 136.350 107.070 1.00 117.50 ? 283 PRO B CB  1 
ATOM 3220 C CG  . PRO B 1 283 ? 113.221 137.023 108.358 1.00 117.69 ? 283 PRO B CG  1 
ATOM 3221 C CD  . PRO B 1 283 ? 112.952 135.984 109.396 1.00 117.87 ? 283 PRO B CD  1 
ATOM 3222 N N   . THR B 1 284 ? 115.881 135.127 107.383 1.00 114.21 ? 284 THR B N   1 
ATOM 3223 C CA  . THR B 1 284 ? 117.234 134.883 106.898 1.00 113.20 ? 284 THR B CA  1 
ATOM 3224 C C   . THR B 1 284 ? 117.518 133.391 106.821 1.00 107.93 ? 284 THR B C   1 
ATOM 3225 O O   . THR B 1 284 ? 118.132 132.914 105.859 1.00 109.43 ? 284 THR B O   1 
ATOM 3226 C CB  . THR B 1 284 ? 118.250 135.579 107.802 1.00 115.44 ? 284 THR B CB  1 
ATOM 3227 O OG1 . THR B 1 284 ? 118.083 136.998 107.701 1.00 121.23 ? 284 THR B OG1 1 
ATOM 3228 C CG2 . THR B 1 284 ? 119.667 135.215 107.396 1.00 111.10 ? 284 THR B CG2 1 
ATOM 3229 N N   . LEU B 1 285 ? 117.065 132.637 107.824 1.00 106.26 ? 285 LEU B N   1 
ATOM 3230 C CA  . LEU B 1 285 ? 117.215 131.189 107.787 1.00 102.54 ? 285 LEU B CA  1 
ATOM 3231 C C   . LEU B 1 285 ? 116.473 130.603 106.594 1.00 107.23 ? 285 LEU B C   1 
ATOM 3232 O O   . LEU B 1 285 ? 116.980 129.698 105.925 1.00 111.57 ? 285 LEU B O   1 
ATOM 3233 C CB  . LEU B 1 285 ? 116.724 130.589 109.108 1.00 106.14 ? 285 LEU B CB  1 
ATOM 3234 C CG  . LEU B 1 285 ? 116.811 129.102 109.489 1.00 104.95 ? 285 LEU B CG  1 
ATOM 3235 C CD1 . LEU B 1 285 ? 116.028 128.156 108.585 1.00 106.60 ? 285 LEU B CD1 1 
ATOM 3236 C CD2 . LEU B 1 285 ? 118.271 128.680 109.547 1.00 100.50 ? 285 LEU B CD2 1 
ATOM 3237 N N   . ARG B 1 286 ? 115.274 131.112 106.309 1.00 109.70 ? 286 ARG B N   1 
ATOM 3238 C CA  . ARG B 1 286 ? 114.512 130.612 105.168 1.00 112.32 ? 286 ARG B CA  1 
ATOM 3239 C C   . ARG B 1 286 ? 115.251 130.861 103.857 1.00 110.40 ? 286 ARG B C   1 
ATOM 3240 O O   . ARG B 1 286 ? 115.362 129.964 103.009 1.00 110.93 ? 286 ARG B O   1 
ATOM 3241 C CB  . ARG B 1 286 ? 113.132 131.267 105.140 1.00 116.98 ? 286 ARG B CB  1 
ATOM 3242 C CG  . ARG B 1 286 ? 112.058 130.421 104.490 1.00 124.25 ? 286 ARG B CG  1 
ATOM 3243 C CD  . ARG B 1 286 ? 110.981 131.291 103.867 1.00 130.70 ? 286 ARG B CD  1 
ATOM 3244 N NE  . ARG B 1 286 ? 110.742 132.503 104.641 1.00 137.50 ? 286 ARG B NE  1 
ATOM 3245 C CZ  . ARG B 1 286 ? 110.812 133.733 104.150 1.00 135.60 ? 286 ARG B CZ  1 
ATOM 3246 N NH1 . ARG B 1 286 ? 111.120 133.955 102.883 1.00 133.32 ? 286 ARG B NH1 1 
ATOM 3247 N NH2 . ARG B 1 286 ? 110.565 134.766 104.950 1.00 134.63 ? 286 ARG B NH2 1 
ATOM 3248 N N   . ASP B 1 287 ? 115.764 132.079 103.676 1.00 108.84 ? 287 ASP B N   1 
ATOM 3249 C CA  . ASP B 1 287 ? 116.485 132.402 102.447 1.00 106.52 ? 287 ASP B CA  1 
ATOM 3250 C C   . ASP B 1 287 ? 117.740 131.551 102.305 1.00 102.85 ? 287 ASP B C   1 
ATOM 3251 O O   . ASP B 1 287 ? 118.038 131.043 101.216 1.00 101.76 ? 287 ASP B O   1 
ATOM 3252 C CB  . ASP B 1 287 ? 116.843 133.886 102.423 1.00 113.72 ? 287 ASP B CB  1 
ATOM 3253 C CG  . ASP B 1 287 ? 115.662 134.763 102.071 1.00 127.29 ? 287 ASP B CG  1 
ATOM 3254 O OD1 . ASP B 1 287 ? 115.816 136.002 102.077 1.00 133.88 ? 287 ASP B OD1 1 
ATOM 3255 O OD2 . ASP B 1 287 ? 114.577 134.213 101.794 1.00 128.84 ? 287 ASP B OD2 1 
ATOM 3256 N N   . VAL B 1 288 ? 118.485 131.382 103.398 1.00 104.71 ? 288 VAL B N   1 
ATOM 3257 C CA  . VAL B 1 288 ? 119.698 130.573 103.360 1.00 98.56  ? 288 VAL B CA  1 
ATOM 3258 C C   . VAL B 1 288 ? 119.361 129.131 103.013 1.00 98.52  ? 288 VAL B C   1 
ATOM 3259 O O   . VAL B 1 288 ? 120.053 128.490 102.213 1.00 99.81  ? 288 VAL B O   1 
ATOM 3260 C CB  . VAL B 1 288 ? 120.443 130.677 104.704 1.00 96.88  ? 288 VAL B CB  1 
ATOM 3261 C CG1 . VAL B 1 288 ? 121.283 129.439 104.952 1.00 98.03  ? 288 VAL B CG1 1 
ATOM 3262 C CG2 . VAL B 1 288 ? 121.302 131.924 104.731 1.00 98.12  ? 288 VAL B CG2 1 
ATOM 3263 N N   . LEU B 1 289 ? 118.292 128.598 103.608 1.00 100.50 ? 289 LEU B N   1 
ATOM 3264 C CA  . LEU B 1 289 ? 117.898 127.225 103.331 1.00 97.35  ? 289 LEU B CA  1 
ATOM 3265 C C   . LEU B 1 289 ? 117.519 127.047 101.870 1.00 96.52  ? 289 LEU B C   1 
ATOM 3266 O O   . LEU B 1 289 ? 117.891 126.049 101.245 1.00 97.63  ? 289 LEU B O   1 
ATOM 3267 C CB  . LEU B 1 289 ? 116.739 126.822 104.240 1.00 98.30  ? 289 LEU B CB  1 
ATOM 3268 C CG  . LEU B 1 289 ? 117.117 126.185 105.578 1.00 101.41 ? 289 LEU B CG  1 
ATOM 3269 C CD1 . LEU B 1 289 ? 115.980 125.326 106.094 1.00 108.92 ? 289 LEU B CD1 1 
ATOM 3270 C CD2 . LEU B 1 289 ? 118.394 125.373 105.455 1.00 99.97  ? 289 LEU B CD2 1 
ATOM 3271 N N   . ARG B 1 290 ? 116.778 128.002 101.306 1.00 97.77  ? 290 ARG B N   1 
ATOM 3272 C CA  . ARG B 1 290 ? 116.397 127.877 99.902  1.00 95.97  ? 290 ARG B CA  1 
ATOM 3273 C C   . ARG B 1 290 ? 117.616 127.949 98.993  1.00 95.45  ? 290 ARG B C   1 
ATOM 3274 O O   . ARG B 1 290 ? 117.735 127.171 98.036  1.00 97.66  ? 290 ARG B O   1 
ATOM 3275 C CB  . ARG B 1 290 ? 115.383 128.952 99.528  1.00 100.74 ? 290 ARG B CB  1 
ATOM 3276 C CG  . ARG B 1 290 ? 114.413 128.519 98.440  1.00 104.09 ? 290 ARG B CG  1 
ATOM 3277 C CD  . ARG B 1 290 ? 113.838 129.700 97.689  1.00 107.01 ? 290 ARG B CD  1 
ATOM 3278 N NE  . ARG B 1 290 ? 112.417 129.507 97.426  1.00 114.70 ? 290 ARG B NE  1 
ATOM 3279 C CZ  . ARG B 1 290 ? 111.737 130.108 96.460  1.00 114.99 ? 290 ARG B CZ  1 
ATOM 3280 N NH1 . ARG B 1 290 ? 112.325 130.930 95.610  1.00 112.32 ? 290 ARG B NH1 1 
ATOM 3281 N NH2 . ARG B 1 290 ? 110.430 129.891 96.354  1.00 116.73 ? 290 ARG B NH2 1 
ATOM 3282 N N   . ILE B 1 291 ? 118.545 128.863 99.284  1.00 96.03  ? 291 ILE B N   1 
ATOM 3283 C CA  . ILE B 1 291 ? 119.750 128.974 98.464  1.00 91.29  ? 291 ILE B CA  1 
ATOM 3284 C C   . ILE B 1 291 ? 120.561 127.688 98.534  1.00 91.42  ? 291 ILE B C   1 
ATOM 3285 O O   . ILE B 1 291 ? 121.048 127.190 97.513  1.00 91.38  ? 291 ILE B O   1 
ATOM 3286 C CB  . ILE B 1 291 ? 120.580 130.196 98.899  1.00 90.41  ? 291 ILE B CB  1 
ATOM 3287 C CG1 . ILE B 1 291 ? 120.138 131.436 98.129  1.00 95.68  ? 291 ILE B CG1 1 
ATOM 3288 C CG2 . ILE B 1 291 ? 122.055 129.955 98.672  1.00 87.77  ? 291 ILE B CG2 1 
ATOM 3289 C CD1 . ILE B 1 291 ? 120.638 132.723 98.727  1.00 101.44 ? 291 ILE B CD1 1 
ATOM 3290 N N   . LEU B 1 292 ? 120.710 127.125 99.735  1.00 91.57  ? 292 LEU B N   1 
ATOM 3291 C CA  . LEU B 1 292 ? 121.492 125.903 99.884  1.00 88.30  ? 292 LEU B CA  1 
ATOM 3292 C C   . LEU B 1 292 ? 120.809 124.707 99.236  1.00 88.97  ? 292 LEU B C   1 
ATOM 3293 O O   . LEU B 1 292 ? 121.490 123.829 98.699  1.00 91.77  ? 292 LEU B O   1 
ATOM 3294 C CB  . LEU B 1 292 ? 121.761 125.625 101.361 1.00 87.82  ? 292 LEU B CB  1 
ATOM 3295 C CG  . LEU B 1 292 ? 122.759 126.559 102.042 1.00 88.45  ? 292 LEU B CG  1 
ATOM 3296 C CD1 . LEU B 1 292 ? 123.131 126.025 103.409 1.00 94.53  ? 292 LEU B CD1 1 
ATOM 3297 C CD2 . LEU B 1 292 ? 123.996 126.730 101.186 1.00 86.14  ? 292 LEU B CD2 1 
ATOM 3298 N N   . MET B 1 293 ? 119.479 124.646 99.278  1.00 87.22  ? 293 MET B N   1 
ATOM 3299 C CA  . MET B 1 293 ? 118.761 123.586 98.587  1.00 86.71  ? 293 MET B CA  1 
ATOM 3300 C C   . MET B 1 293 ? 118.669 123.827 97.091  1.00 89.59  ? 293 MET B C   1 
ATOM 3301 O O   . MET B 1 293 ? 118.163 122.959 96.372  1.00 92.92  ? 293 MET B O   1 
ATOM 3302 C CB  . MET B 1 293 ? 117.355 123.427 99.165  1.00 87.95  ? 293 MET B CB  1 
ATOM 3303 C CG  . MET B 1 293 ? 117.321 122.791 100.536 1.00 91.22  ? 293 MET B CG  1 
ATOM 3304 S SD  . MET B 1 293 ? 117.115 121.005 100.464 1.00 104.31 ? 293 MET B SD  1 
ATOM 3305 C CE  . MET B 1 293 ? 115.588 120.884 99.546  1.00 99.84  ? 293 MET B CE  1 
ATOM 3306 N N   . GLU B 1 294 ? 119.122 124.989 96.620  1.00 91.59  ? 294 GLU B N   1 
ATOM 3307 C CA  . GLU B 1 294 ? 119.239 125.289 95.192  1.00 91.59  ? 294 GLU B CA  1 
ATOM 3308 C C   . GLU B 1 294 ? 117.868 125.409 94.532  1.00 93.53  ? 294 GLU B C   1 
ATOM 3309 O O   . GLU B 1 294 ? 117.585 124.774 93.517  1.00 94.07  ? 294 GLU B O   1 
ATOM 3310 C CB  . GLU B 1 294 ? 120.100 124.248 94.474  1.00 86.96  ? 294 GLU B CB  1 
ATOM 3311 C CG  . GLU B 1 294 ? 121.579 124.461 94.652  1.00 91.64  ? 294 GLU B CG  1 
ATOM 3312 C CD  . GLU B 1 294 ? 122.358 124.102 93.416  1.00 93.30  ? 294 GLU B CD  1 
ATOM 3313 O OE1 . GLU B 1 294 ? 122.084 123.040 92.829  1.00 91.77  ? 294 GLU B OE1 1 
ATOM 3314 O OE2 . GLU B 1 294 ? 123.246 124.885 93.028  1.00 94.32  ? 294 GLU B OE2 1 
ATOM 3315 N N   . GLY B 1 295 ? 117.011 126.235 95.125  1.00 92.59  ? 295 GLY B N   1 
ATOM 3316 C CA  . GLY B 1 295 ? 115.776 126.627 94.488  1.00 94.73  ? 295 GLY B CA  1 
ATOM 3317 C C   . GLY B 1 295 ? 115.965 127.857 93.624  1.00 90.36  ? 295 GLY B C   1 
ATOM 3318 O O   . GLY B 1 295 ? 117.042 128.444 93.549  1.00 90.45  ? 295 GLY B O   1 
ATOM 3319 N N   . THR B 1 296 ? 114.885 128.248 92.964  1.00 89.43  ? 296 THR B N   1 
ATOM 3320 C CA  . THR B 1 296 ? 114.908 129.459 92.165  1.00 91.61  ? 296 THR B CA  1 
ATOM 3321 C C   . THR B 1 296 ? 115.157 130.660 93.075  1.00 98.69  ? 296 THR B C   1 
ATOM 3322 O O   . THR B 1 296 ? 114.695 130.674 94.220  1.00 108.13 ? 296 THR B O   1 
ATOM 3323 C CB  . THR B 1 296 ? 113.584 129.623 91.420  1.00 95.71  ? 296 THR B CB  1 
ATOM 3324 O OG1 . THR B 1 296 ? 113.079 128.332 91.062  1.00 95.73  ? 296 THR B OG1 1 
ATOM 3325 C CG2 . THR B 1 296 ? 113.768 130.440 90.159  1.00 97.49  ? 296 THR B CG2 1 
ATOM 3326 N N   . PRO B 1 297 ? 115.906 131.662 92.621  1.00 97.17  ? 297 PRO B N   1 
ATOM 3327 C CA  . PRO B 1 297 ? 116.081 132.868 93.435  1.00 104.19 ? 297 PRO B CA  1 
ATOM 3328 C C   . PRO B 1 297 ? 114.757 133.586 93.655  1.00 111.18 ? 297 PRO B C   1 
ATOM 3329 O O   . PRO B 1 297 ? 113.820 133.466 92.863  1.00 110.81 ? 297 PRO B O   1 
ATOM 3330 C CB  . PRO B 1 297 ? 117.052 133.720 92.609  1.00 103.03 ? 297 PRO B CB  1 
ATOM 3331 C CG  . PRO B 1 297 ? 117.050 133.118 91.245  1.00 96.24  ? 297 PRO B CG  1 
ATOM 3332 C CD  . PRO B 1 297 ? 116.776 131.671 91.436  1.00 91.66  ? 297 PRO B CD  1 
ATOM 3333 N N   . ARG B 1 298 ? 114.687 134.332 94.760  1.00 113.81 ? 298 ARG B N   1 
ATOM 3334 C CA  . ARG B 1 298 ? 113.447 135.011 95.125  1.00 116.29 ? 298 ARG B CA  1 
ATOM 3335 C C   . ARG B 1 298 ? 113.012 135.993 94.046  1.00 113.84 ? 298 ARG B C   1 
ATOM 3336 O O   . ARG B 1 298 ? 111.834 136.044 93.672  1.00 110.76 ? 298 ARG B O   1 
ATOM 3337 C CB  . ARG B 1 298 ? 113.622 135.738 96.460  1.00 122.15 ? 298 ARG B CB  1 
ATOM 3338 C CG  . ARG B 1 298 ? 113.599 134.846 97.689  1.00 123.83 ? 298 ARG B CG  1 
ATOM 3339 C CD  . ARG B 1 298 ? 112.870 133.544 97.422  1.00 124.20 ? 298 ARG B CD  1 
ATOM 3340 N NE  . ARG B 1 298 ? 112.081 133.108 98.567  1.00 129.33 ? 298 ARG B NE  1 
ATOM 3341 C CZ  . ARG B 1 298 ? 112.580 132.497 99.632  1.00 127.83 ? 298 ARG B CZ  1 
ATOM 3342 N NH1 . ARG B 1 298 ? 113.875 132.251 99.744  1.00 124.11 ? 298 ARG B NH1 1 
ATOM 3343 N NH2 . ARG B 1 298 ? 111.759 132.122 100.608 1.00 126.28 ? 298 ARG B NH2 1 
ATOM 3344 N N   . ASN B 1 299 ? 113.953 136.782 93.530  1.00 112.03 ? 299 ASN B N   1 
ATOM 3345 C CA  . ASN B 1 299 ? 113.601 137.810 92.558  1.00 111.34 ? 299 ASN B CA  1 
ATOM 3346 C C   . ASN B 1 299 ? 113.143 137.198 91.242  1.00 114.05 ? 299 ASN B C   1 
ATOM 3347 O O   . ASN B 1 299 ? 112.215 137.708 90.604  1.00 115.94 ? 299 ASN B O   1 
ATOM 3348 C CB  . ASN B 1 299 ? 114.794 138.735 92.329  1.00 115.74 ? 299 ASN B CB  1 
ATOM 3349 C CG  . ASN B 1 299 ? 115.687 138.841 93.546  1.00 124.57 ? 299 ASN B CG  1 
ATOM 3350 O OD1 . ASN B 1 299 ? 115.223 139.129 94.649  1.00 128.84 ? 299 ASN B OD1 1 
ATOM 3351 N ND2 . ASN B 1 299 ? 116.978 138.604 93.353  1.00 121.86 ? 299 ASN B ND2 1 
ATOM 3352 N N   . VAL B 1 300 ? 113.775 136.110 90.823  1.00 114.42 ? 300 VAL B N   1 
ATOM 3353 C CA  . VAL B 1 300 ? 113.570 135.548 89.494  1.00 111.19 ? 300 VAL B CA  1 
ATOM 3354 C C   . VAL B 1 300 ? 112.463 134.506 89.549  1.00 107.20 ? 300 VAL B C   1 
ATOM 3355 O O   . VAL B 1 300 ? 112.497 133.590 90.378  1.00 108.01 ? 300 VAL B O   1 
ATOM 3356 C CB  . VAL B 1 300 ? 114.872 134.939 88.955  1.00 104.83 ? 300 VAL B CB  1 
ATOM 3357 C CG1 . VAL B 1 300 ? 114.582 134.027 87.784  1.00 103.37 ? 300 VAL B CG1 1 
ATOM 3358 C CG2 . VAL B 1 300 ? 115.842 136.037 88.559  1.00 99.09  ? 300 VAL B CG2 1 
ATOM 3359 N N   . GLY B 1 301 ? 111.482 134.642 88.663  1.00 101.16 ? 301 GLY B N   1 
ATOM 3360 C CA  . GLY B 1 301 ? 110.402 133.678 88.545  1.00 102.89 ? 301 GLY B CA  1 
ATOM 3361 C C   . GLY B 1 301 ? 110.661 132.716 87.399  1.00 103.62 ? 301 GLY B C   1 
ATOM 3362 O O   . GLY B 1 301 ? 111.212 133.096 86.368  1.00 107.23 ? 301 GLY B O   1 
ATOM 3363 N N   . PHE B 1 302 ? 110.255 131.461 87.598  1.00 99.37  ? 302 PHE B N   1 
ATOM 3364 C CA  . PHE B 1 302 ? 110.472 130.436 86.583  1.00 92.54  ? 302 PHE B CA  1 
ATOM 3365 C C   . PHE B 1 302 ? 109.692 130.745 85.311  1.00 94.23  ? 302 PHE B C   1 
ATOM 3366 O O   . PHE B 1 302 ? 110.225 130.647 84.198  1.00 96.42  ? 302 PHE B O   1 
ATOM 3367 C CB  . PHE B 1 302 ? 110.073 129.073 87.147  1.00 92.05  ? 302 PHE B CB  1 
ATOM 3368 C CG  . PHE B 1 302 ? 110.312 127.926 86.212  1.00 90.87  ? 302 PHE B CG  1 
ATOM 3369 C CD1 . PHE B 1 302 ? 111.523 127.261 86.212  1.00 88.41  ? 302 PHE B CD1 1 
ATOM 3370 C CD2 . PHE B 1 302 ? 109.319 127.497 85.350  1.00 95.31  ? 302 PHE B CD2 1 
ATOM 3371 C CE1 . PHE B 1 302 ? 111.744 126.201 85.363  1.00 88.25  ? 302 PHE B CE1 1 
ATOM 3372 C CE2 . PHE B 1 302 ? 109.536 126.437 84.498  1.00 94.69  ? 302 PHE B CE2 1 
ATOM 3373 C CZ  . PHE B 1 302 ? 110.749 125.788 84.505  1.00 91.82  ? 302 PHE B CZ  1 
ATOM 3374 N N   . GLU B 1 303 ? 108.424 131.120 85.459  1.00 97.86  ? 303 GLU B N   1 
ATOM 3375 C CA  . GLU B 1 303 ? 107.582 131.366 84.291  1.00 102.42 ? 303 GLU B CA  1 
ATOM 3376 C C   . GLU B 1 303 ? 108.067 132.529 83.437  1.00 104.63 ? 303 GLU B C   1 
ATOM 3377 O O   . GLU B 1 303 ? 108.098 132.382 82.202  1.00 106.71 ? 303 GLU B O   1 
ATOM 3378 C CB  . GLU B 1 303 ? 106.131 131.571 84.735  1.00 105.86 ? 303 GLU B CB  1 
ATOM 3379 C CG  . GLU B 1 303 ? 105.266 130.343 84.572  1.00 110.24 ? 303 GLU B CG  1 
ATOM 3380 C CD  . GLU B 1 303 ? 105.486 129.654 83.248  1.00 116.12 ? 303 GLU B CD  1 
ATOM 3381 O OE1 . GLU B 1 303 ? 105.311 130.304 82.197  1.00 114.85 ? 303 GLU B OE1 1 
ATOM 3382 O OE2 . GLU B 1 303 ? 105.842 128.459 83.262  1.00 118.11 ? 303 GLU B OE2 1 
ATOM 3383 N N   . PRO B 1 304 ? 108.412 133.702 83.989  1.00 105.03 ? 304 PRO B N   1 
ATOM 3384 C CA  . PRO B 1 304 ? 108.929 134.771 83.118  1.00 102.35 ? 304 PRO B CA  1 
ATOM 3385 C C   . PRO B 1 304 ? 110.167 134.362 82.346  1.00 102.13 ? 304 PRO B C   1 
ATOM 3386 O O   . PRO B 1 304 ? 110.298 134.706 81.166  1.00 102.13 ? 304 PRO B O   1 
ATOM 3387 C CB  . PRO B 1 304 ? 109.224 135.910 84.102  1.00 101.51 ? 304 PRO B CB  1 
ATOM 3388 C CG  . PRO B 1 304 ? 108.322 135.661 85.240  1.00 104.14 ? 304 PRO B CG  1 
ATOM 3389 C CD  . PRO B 1 304 ? 108.248 134.175 85.375  1.00 103.85 ? 304 PRO B CD  1 
ATOM 3390 N N   . VAL B 1 305 ? 111.072 133.614 82.978  1.00 98.75  ? 305 VAL B N   1 
ATOM 3391 C CA  . VAL B 1 305 ? 112.270 133.156 82.284  1.00 92.38  ? 305 VAL B CA  1 
ATOM 3392 C C   . VAL B 1 305 ? 111.902 132.202 81.158  1.00 92.62  ? 305 VAL B C   1 
ATOM 3393 O O   . VAL B 1 305 ? 112.451 132.287 80.052  1.00 95.82  ? 305 VAL B O   1 
ATOM 3394 C CB  . VAL B 1 305 ? 113.249 132.510 83.278  1.00 86.29  ? 305 VAL B CB  1 
ATOM 3395 C CG1 . VAL B 1 305 ? 114.468 131.993 82.549  1.00 85.39  ? 305 VAL B CG1 1 
ATOM 3396 C CG2 . VAL B 1 305 ? 113.657 133.509 84.331  1.00 89.02  ? 305 VAL B CG2 1 
ATOM 3397 N N   . ARG B 1 306 ? 110.972 131.280 81.414  1.00 92.13  ? 306 ARG B N   1 
ATOM 3398 C CA  . ARG B 1 306 ? 110.578 130.340 80.371  1.00 91.98  ? 306 ARG B CA  1 
ATOM 3399 C C   . ARG B 1 306 ? 109.963 131.068 79.183  1.00 100.19 ? 306 ARG B C   1 
ATOM 3400 O O   . ARG B 1 306 ? 110.321 130.806 78.028  1.00 105.24 ? 306 ARG B O   1 
ATOM 3401 C CB  . ARG B 1 306 ? 109.609 129.300 80.930  1.00 96.79  ? 306 ARG B CB  1 
ATOM 3402 C CG  . ARG B 1 306 ? 109.778 127.930 80.300  1.00 97.58  ? 306 ARG B CG  1 
ATOM 3403 C CD  . ARG B 1 306 ? 108.453 127.212 80.101  1.00 106.66 ? 306 ARG B CD  1 
ATOM 3404 N NE  . ARG B 1 306 ? 107.443 128.077 79.504  1.00 114.67 ? 306 ARG B NE  1 
ATOM 3405 C CZ  . ARG B 1 306 ? 106.166 128.094 79.858  1.00 118.57 ? 306 ARG B CZ  1 
ATOM 3406 N NH1 . ARG B 1 306 ? 105.692 127.266 80.774  1.00 118.17 ? 306 ARG B NH1 1 
ATOM 3407 N NH2 . ARG B 1 306 ? 105.341 128.954 79.268  1.00 117.26 ? 306 ARG B NH2 1 
ATOM 3408 N N   . ASP B 1 307 ? 109.050 132.008 79.446  1.00 101.67 ? 307 ASP B N   1 
ATOM 3409 C CA  . ASP B 1 307 ? 108.444 132.750 78.342  1.00 101.21 ? 307 ASP B CA  1 
ATOM 3410 C C   . ASP B 1 307 ? 109.481 133.576 77.595  1.00 101.90 ? 307 ASP B C   1 
ATOM 3411 O O   . ASP B 1 307 ? 109.435 133.668 76.365  1.00 102.48 ? 307 ASP B O   1 
ATOM 3412 C CB  . ASP B 1 307 ? 107.301 133.642 78.827  1.00 106.88 ? 307 ASP B CB  1 
ATOM 3413 C CG  . ASP B 1 307 ? 106.484 133.006 79.926  1.00 119.69 ? 307 ASP B CG  1 
ATOM 3414 O OD1 . ASP B 1 307 ? 106.117 133.719 80.884  1.00 121.91 ? 307 ASP B OD1 1 
ATOM 3415 O OD2 . ASP B 1 307 ? 106.202 131.794 79.831  1.00 122.23 ? 307 ASP B OD2 1 
ATOM 3416 N N   . THR B 1 308 ? 110.431 134.176 78.315  1.00 99.71  ? 308 THR B N   1 
ATOM 3417 C CA  . THR B 1 308 ? 111.496 134.915 77.647  1.00 99.40  ? 308 THR B CA  1 
ATOM 3418 C C   . THR B 1 308 ? 112.289 134.005 76.721  1.00 100.65 ? 308 THR B C   1 
ATOM 3419 O O   . THR B 1 308 ? 112.632 134.392 75.598  1.00 102.95 ? 308 THR B O   1 
ATOM 3420 C CB  . THR B 1 308 ? 112.417 135.556 78.683  1.00 97.70  ? 308 THR B CB  1 
ATOM 3421 O OG1 . THR B 1 308 ? 111.715 136.600 79.366  1.00 104.17 ? 308 THR B OG1 1 
ATOM 3422 C CG2 . THR B 1 308 ? 113.652 136.136 78.017  1.00 97.48  ? 308 THR B CG2 1 
ATOM 3423 N N   . LEU B 1 309 ? 112.582 132.785 77.173  1.00 101.10 ? 309 LEU B N   1 
ATOM 3424 C CA  . LEU B 1 309 ? 113.321 131.848 76.334  1.00 93.98  ? 309 LEU B CA  1 
ATOM 3425 C C   . LEU B 1 309 ? 112.522 131.451 75.099  1.00 99.76  ? 309 LEU B C   1 
ATOM 3426 O O   . LEU B 1 309 ? 113.076 131.379 73.997  1.00 107.48 ? 309 LEU B O   1 
ATOM 3427 C CB  . LEU B 1 309 ? 113.709 130.614 77.144  1.00 86.02  ? 309 LEU B CB  1 
ATOM 3428 C CG  . LEU B 1 309 ? 114.878 130.827 78.103  1.00 82.10  ? 309 LEU B CG  1 
ATOM 3429 C CD1 . LEU B 1 309 ? 115.272 129.525 78.767  1.00 84.49  ? 309 LEU B CD1 1 
ATOM 3430 C CD2 . LEU B 1 309 ? 116.056 131.434 77.369  1.00 80.25  ? 309 LEU B CD2 1 
ATOM 3431 N N   . LEU B 1 310 ? 111.220 131.196 75.253  1.00 97.95  ? 310 LEU B N   1 
ATOM 3432 C CA  . LEU B 1 310 ? 110.431 130.745 74.110  1.00 100.45 ? 310 LEU B CA  1 
ATOM 3433 C C   . LEU B 1 310 ? 110.085 131.859 73.129  1.00 105.50 ? 310 LEU B C   1 
ATOM 3434 O O   . LEU B 1 310 ? 109.743 131.560 71.981  1.00 108.24 ? 310 LEU B O   1 
ATOM 3435 C CB  . LEU B 1 310 ? 109.141 130.065 74.570  1.00 100.64 ? 310 LEU B CB  1 
ATOM 3436 C CG  . LEU B 1 310 ? 109.273 128.674 75.189  1.00 100.96 ? 310 LEU B CG  1 
ATOM 3437 C CD1 . LEU B 1 310 ? 108.686 128.635 76.577  1.00 96.78  ? 310 LEU B CD1 1 
ATOM 3438 C CD2 . LEU B 1 310 ? 108.599 127.646 74.301  1.00 102.52 ? 310 LEU B CD2 1 
ATOM 3439 N N   . SER B 1 311 ? 110.158 133.125 73.538  1.00 104.59 ? 311 SER B N   1 
ATOM 3440 C CA  . SER B 1 311 ? 109.856 134.210 72.613  1.00 109.53 ? 311 SER B CA  1 
ATOM 3441 C C   . SER B 1 311 ? 111.004 134.527 71.667  1.00 115.85 ? 311 SER B C   1 
ATOM 3442 O O   . SER B 1 311 ? 110.823 135.339 70.754  1.00 115.67 ? 311 SER B O   1 
ATOM 3443 C CB  . SER B 1 311 ? 109.465 135.477 73.376  1.00 111.76 ? 311 SER B CB  1 
ATOM 3444 O OG  . SER B 1 311 ? 108.543 135.190 74.408  1.00 117.23 ? 311 SER B OG  1 
ATOM 3445 N N   . VAL B 1 312 ? 112.168 133.923 71.862  1.00 114.57 ? 312 VAL B N   1 
ATOM 3446 C CA  . VAL B 1 312 ? 113.283 134.121 70.930  1.00 110.63 ? 312 VAL B CA  1 
ATOM 3447 C C   . VAL B 1 312 ? 112.903 133.540 69.573  1.00 116.92 ? 312 VAL B C   1 
ATOM 3448 O O   . VAL B 1 312 ? 112.397 132.405 69.511  1.00 118.09 ? 312 VAL B O   1 
ATOM 3449 C CB  . VAL B 1 312 ? 114.552 133.466 71.474  1.00 105.45 ? 312 VAL B CB  1 
ATOM 3450 C CG1 . VAL B 1 312 ? 115.681 133.583 70.470  1.00 112.88 ? 312 VAL B CG1 1 
ATOM 3451 C CG2 . VAL B 1 312 ? 114.943 134.096 72.796  1.00 108.48 ? 312 VAL B CG2 1 
ATOM 3452 N N   . PRO B 1 313 ? 113.105 134.264 68.473  1.00 121.92 ? 313 PRO B N   1 
ATOM 3453 C CA  . PRO B 1 313 ? 112.711 133.738 67.157  1.00 123.94 ? 313 PRO B CA  1 
ATOM 3454 C C   . PRO B 1 313 ? 113.479 132.472 66.814  1.00 123.08 ? 313 PRO B C   1 
ATOM 3455 O O   . PRO B 1 313 ? 114.706 132.478 66.701  1.00 118.58 ? 313 PRO B O   1 
ATOM 3456 C CB  . PRO B 1 313 ? 113.054 134.887 66.201  1.00 123.72 ? 313 PRO B CB  1 
ATOM 3457 C CG  . PRO B 1 313 ? 113.109 136.103 67.062  1.00 123.67 ? 313 PRO B CG  1 
ATOM 3458 C CD  . PRO B 1 313 ? 113.616 135.641 68.389  1.00 120.49 ? 313 PRO B CD  1 
ATOM 3459 N N   . GLY B 1 314 ? 112.740 131.379 66.643  1.00 121.26 ? 314 GLY B N   1 
ATOM 3460 C CA  . GLY B 1 314 ? 113.341 130.104 66.312  1.00 118.33 ? 314 GLY B CA  1 
ATOM 3461 C C   . GLY B 1 314 ? 113.148 129.053 67.384  1.00 118.54 ? 314 GLY B C   1 
ATOM 3462 O O   . GLY B 1 314 ? 112.978 127.871 67.076  1.00 121.49 ? 314 GLY B O   1 
ATOM 3463 N N   . VAL B 1 315 ? 113.166 129.471 68.650  1.00 116.05 ? 315 VAL B N   1 
ATOM 3464 C CA  . VAL B 1 315 ? 113.021 128.528 69.751  1.00 112.51 ? 315 VAL B CA  1 
ATOM 3465 C C   . VAL B 1 315 ? 111.604 127.975 69.760  1.00 115.61 ? 315 VAL B C   1 
ATOM 3466 O O   . VAL B 1 315 ? 110.626 128.726 69.665  1.00 118.12 ? 315 VAL B O   1 
ATOM 3467 C CB  . VAL B 1 315 ? 113.362 129.203 71.087  1.00 107.66 ? 315 VAL B CB  1 
ATOM 3468 C CG1 . VAL B 1 315 ? 113.117 128.249 72.237  1.00 104.05 ? 315 VAL B CG1 1 
ATOM 3469 C CG2 . VAL B 1 315 ? 114.801 129.671 71.087  1.00 103.45 ? 315 VAL B CG2 1 
ATOM 3470 N N   . ARG B 1 316 ? 111.488 126.654 69.867  1.00 113.88 ? 316 ARG B N   1 
ATOM 3471 C CA  . ARG B 1 316 ? 110.197 125.980 69.916  1.00 114.34 ? 316 ARG B CA  1 
ATOM 3472 C C   . ARG B 1 316 ? 109.828 125.479 71.301  1.00 112.81 ? 316 ARG B C   1 
ATOM 3473 O O   . ARG B 1 316 ? 108.662 125.563 71.688  1.00 117.63 ? 316 ARG B O   1 
ATOM 3474 C CB  . ARG B 1 316 ? 110.178 124.804 68.937  1.00 117.51 ? 316 ARG B CB  1 
ATOM 3475 C CG  . ARG B 1 316 ? 110.710 125.148 67.564  1.00 120.53 ? 316 ARG B CG  1 
ATOM 3476 C CD  . ARG B 1 316 ? 109.678 125.912 66.759  1.00 125.98 ? 316 ARG B CD  1 
ATOM 3477 N NE  . ARG B 1 316 ? 108.434 125.163 66.631  1.00 135.42 ? 316 ARG B NE  1 
ATOM 3478 C CZ  . ARG B 1 316 ? 108.225 124.206 65.738  1.00 141.00 ? 316 ARG B CZ  1 
ATOM 3479 N NH1 . ARG B 1 316 ? 109.159 123.857 64.868  1.00 137.83 ? 316 ARG B NH1 1 
ATOM 3480 N NH2 . ARG B 1 316 ? 107.050 123.584 65.716  1.00 142.89 ? 316 ARG B NH2 1 
ATOM 3481 N N   . ALA B 1 317 ? 110.788 124.957 72.058  1.00 106.41 ? 317 ALA B N   1 
ATOM 3482 C CA  . ALA B 1 317 ? 110.511 124.470 73.401  1.00 103.74 ? 317 ALA B CA  1 
ATOM 3483 C C   . ALA B 1 317 ? 111.809 124.433 74.189  1.00 102.67 ? 317 ALA B C   1 
ATOM 3484 O O   . ALA B 1 317 ? 112.901 124.452 73.620  1.00 105.88 ? 317 ALA B O   1 
ATOM 3485 C CB  . ALA B 1 317 ? 109.858 123.086 73.373  1.00 103.17 ? 317 ALA B CB  1 
ATOM 3486 N N   . THR B 1 318 ? 111.671 124.385 75.511  1.00 100.65 ? 318 THR B N   1 
ATOM 3487 C CA  . THR B 1 318 ? 112.798 124.239 76.421  1.00 99.22  ? 318 THR B CA  1 
ATOM 3488 C C   . THR B 1 318 ? 112.598 122.971 77.237  1.00 101.01 ? 318 THR B C   1 
ATOM 3489 O O   . THR B 1 318 ? 111.492 122.709 77.719  1.00 110.15 ? 318 THR B O   1 
ATOM 3490 C CB  . THR B 1 318 ? 112.933 125.452 77.345  1.00 95.62  ? 318 THR B CB  1 
ATOM 3491 O OG1 . THR B 1 318 ? 111.982 125.354 78.410  1.00 103.68 ? 318 THR B OG1 1 
ATOM 3492 C CG2 . THR B 1 318 ? 112.689 126.735 76.575  1.00 90.83  ? 318 THR B CG2 1 
ATOM 3493 N N   . HIS B 1 319 ? 113.662 122.184 77.386  1.00 92.37  ? 319 HIS B N   1 
ATOM 3494 C CA  . HIS B 1 319 ? 113.540 120.886 78.040  1.00 97.25  ? 319 HIS B CA  1 
ATOM 3495 C C   . HIS B 1 319 ? 113.863 120.959 79.529  1.00 98.74  ? 319 HIS B C   1 
ATOM 3496 O O   . HIS B 1 319 ? 113.011 120.653 80.368  1.00 109.03 ? 319 HIS B O   1 
ATOM 3497 C CB  . HIS B 1 319 ? 114.441 119.862 77.344  1.00 100.02 ? 319 HIS B CB  1 
ATOM 3498 C CG  . HIS B 1 319 ? 114.224 119.776 75.867  1.00 106.70 ? 319 HIS B CG  1 
ATOM 3499 N ND1 . HIS B 1 319 ? 113.034 120.129 75.269  1.00 104.83 ? 319 HIS B ND1 1 
ATOM 3500 C CD2 . HIS B 1 319 ? 115.044 119.376 74.867  1.00 110.03 ? 319 HIS B CD2 1 
ATOM 3501 C CE1 . HIS B 1 319 ? 113.131 119.951 73.963  1.00 107.68 ? 319 HIS B CE1 1 
ATOM 3502 N NE2 . HIS B 1 319 ? 114.340 119.495 73.693  1.00 113.32 ? 319 HIS B NE2 1 
ATOM 3503 N N   . GLU B 1 320 ? 115.083 121.359 79.872  1.00 87.40  ? 320 GLU B N   1 
ATOM 3504 C CA  . GLU B 1 320 ? 115.542 121.364 81.259  1.00 84.49  ? 320 GLU B CA  1 
ATOM 3505 C C   . GLU B 1 320 ? 115.994 122.773 81.616  1.00 81.89  ? 320 GLU B C   1 
ATOM 3506 O O   . GLU B 1 320 ? 117.150 123.139 81.400  1.00 88.69  ? 320 GLU B O   1 
ATOM 3507 C CB  . GLU B 1 320 ? 116.659 120.358 81.469  1.00 89.95  ? 320 GLU B CB  1 
ATOM 3508 C CG  . GLU B 1 320 ? 116.562 119.133 80.586  1.00 100.55 ? 320 GLU B CG  1 
ATOM 3509 C CD  . GLU B 1 320 ? 116.984 117.868 81.303  1.00 115.09 ? 320 GLU B CD  1 
ATOM 3510 O OE1 . GLU B 1 320 ? 117.820 117.959 82.226  1.00 112.39 ? 320 GLU B OE1 1 
ATOM 3511 O OE2 . GLU B 1 320 ? 116.480 116.784 80.943  1.00 125.06 ? 320 GLU B OE2 1 
ATOM 3512 N N   . LEU B 1 321 ? 115.080 123.557 82.175  1.00 76.50  ? 321 LEU B N   1 
ATOM 3513 C CA  . LEU B 1 321 ? 115.378 124.915 82.609  1.00 69.06  ? 321 LEU B CA  1 
ATOM 3514 C C   . LEU B 1 321 ? 115.758 124.874 84.083  1.00 71.28  ? 321 LEU B C   1 
ATOM 3515 O O   . LEU B 1 321 ? 114.917 124.587 84.939  1.00 84.22  ? 321 LEU B O   1 
ATOM 3516 C CB  . LEU B 1 321 ? 114.180 125.828 82.366  1.00 68.99  ? 321 LEU B CB  1 
ATOM 3517 C CG  . LEU B 1 321 ? 114.306 127.287 82.794  1.00 69.42  ? 321 LEU B CG  1 
ATOM 3518 C CD1 . LEU B 1 321 ? 115.501 127.933 82.135  1.00 72.83  ? 321 LEU B CD1 1 
ATOM 3519 C CD2 . LEU B 1 321 ? 113.042 128.038 82.441  1.00 81.66  ? 321 LEU B CD2 1 
ATOM 3520 N N   . HIS B 1 322 ? 117.023 125.150 84.378  1.00 68.23  ? 322 HIS B N   1 
ATOM 3521 C CA  . HIS B 1 322 ? 117.544 125.134 85.738  1.00 71.32  ? 322 HIS B CA  1 
ATOM 3522 C C   . HIS B 1 322 ? 117.864 126.559 86.156  1.00 69.81  ? 322 HIS B C   1 
ATOM 3523 O O   . HIS B 1 322 ? 118.644 127.243 85.487  1.00 72.43  ? 322 HIS B O   1 
ATOM 3524 C CB  . HIS B 1 322 ? 118.797 124.267 85.837  1.00 73.90  ? 322 HIS B CB  1 
ATOM 3525 C CG  . HIS B 1 322 ? 118.539 122.805 85.667  1.00 78.19  ? 322 HIS B CG  1 
ATOM 3526 N ND1 . HIS B 1 322 ? 117.864 122.055 86.603  1.00 79.88  ? 322 HIS B ND1 1 
ATOM 3527 C CD2 . HIS B 1 322 ? 118.872 121.953 84.670  1.00 78.26  ? 322 HIS B CD2 1 
ATOM 3528 C CE1 . HIS B 1 322 ? 117.789 120.803 86.190  1.00 84.46  ? 322 HIS B CE1 1 
ATOM 3529 N NE2 . HIS B 1 322 ? 118.392 120.715 85.019  1.00 84.52  ? 322 HIS B NE2 1 
ATOM 3530 N N   . LEU B 1 323 ? 117.271 127.003 87.258  1.00 72.41  ? 323 LEU B N   1 
ATOM 3531 C CA  . LEU B 1 323 ? 117.552 128.315 87.820  1.00 71.27  ? 323 LEU B CA  1 
ATOM 3532 C C   . LEU B 1 323 ? 117.935 128.144 89.279  1.00 79.65  ? 323 LEU B C   1 
ATOM 3533 O O   . LEU B 1 323 ? 117.203 127.510 90.043  1.00 91.96  ? 323 LEU B O   1 
ATOM 3534 C CB  . LEU B 1 323 ? 116.347 129.248 87.695  1.00 69.60  ? 323 LEU B CB  1 
ATOM 3535 C CG  . LEU B 1 323 ? 115.640 129.258 86.342  1.00 70.56  ? 323 LEU B CG  1 
ATOM 3536 C CD1 . LEU B 1 323 ? 114.336 130.015 86.431  1.00 79.47  ? 323 LEU B CD1 1 
ATOM 3537 C CD2 . LEU B 1 323 ? 116.534 129.866 85.287  1.00 73.71  ? 323 LEU B CD2 1 
ATOM 3538 N N   . TRP B 1 324 ? 119.082 128.694 89.659  1.00 70.07  ? 324 TRP B N   1 
ATOM 3539 C CA  . TRP B 1 324 ? 119.531 128.616 91.040  1.00 74.11  ? 324 TRP B CA  1 
ATOM 3540 C C   . TRP B 1 324 ? 120.476 129.774 91.302  1.00 77.75  ? 324 TRP B C   1 
ATOM 3541 O O   . TRP B 1 324 ? 120.968 130.417 90.373  1.00 83.77  ? 324 TRP B O   1 
ATOM 3542 C CB  . TRP B 1 324 ? 120.199 127.270 91.341  1.00 76.37  ? 324 TRP B CB  1 
ATOM 3543 C CG  . TRP B 1 324 ? 121.562 127.094 90.758  1.00 73.96  ? 324 TRP B CG  1 
ATOM 3544 C CD1 . TRP B 1 324 ? 122.750 127.278 91.393  1.00 76.17  ? 324 TRP B CD1 1 
ATOM 3545 C CD2 . TRP B 1 324 ? 121.880 126.690 89.424  1.00 69.94  ? 324 TRP B CD2 1 
ATOM 3546 N NE1 . TRP B 1 324 ? 123.790 127.012 90.541  1.00 73.37  ? 324 TRP B NE1 1 
ATOM 3547 C CE2 . TRP B 1 324 ? 123.281 126.651 89.323  1.00 67.63  ? 324 TRP B CE2 1 
ATOM 3548 C CE3 . TRP B 1 324 ? 121.116 126.361 88.304  1.00 71.85  ? 324 TRP B CE3 1 
ATOM 3549 C CZ2 . TRP B 1 324 ? 123.932 126.296 88.151  1.00 70.19  ? 324 TRP B CZ2 1 
ATOM 3550 C CZ3 . TRP B 1 324 ? 121.764 126.008 87.143  1.00 71.82  ? 324 TRP B CZ3 1 
ATOM 3551 C CH2 . TRP B 1 324 ? 123.157 125.979 87.073  1.00 71.87  ? 324 TRP B CH2 1 
ATOM 3552 N N   . ALA B 1 325 ? 120.714 130.039 92.581  1.00 76.90  ? 325 ALA B N   1 
ATOM 3553 C CA  . ALA B 1 325 ? 121.510 131.180 93.006  1.00 81.36  ? 325 ALA B CA  1 
ATOM 3554 C C   . ALA B 1 325 ? 122.661 130.711 93.880  1.00 83.63  ? 325 ALA B C   1 
ATOM 3555 O O   . ALA B 1 325 ? 122.451 129.964 94.840  1.00 92.42  ? 325 ALA B O   1 
ATOM 3556 C CB  . ALA B 1 325 ? 120.654 132.191 93.768  1.00 89.72  ? 325 ALA B CB  1 
ATOM 3557 N N   . LEU B 1 326 ? 123.875 131.144 93.542  1.00 81.94  ? 326 LEU B N   1 
ATOM 3558 C CA  . LEU B 1 326 ? 125.009 130.904 94.426  1.00 86.91  ? 326 LEU B CA  1 
ATOM 3559 C C   . LEU B 1 326 ? 124.849 131.663 95.734  1.00 92.94  ? 326 LEU B C   1 
ATOM 3560 O O   . LEU B 1 326 ? 125.133 131.127 96.810  1.00 95.33  ? 326 LEU B O   1 
ATOM 3561 C CB  . LEU B 1 326 ? 126.308 131.305 93.736  1.00 89.71  ? 326 LEU B CB  1 
ATOM 3562 C CG  . LEU B 1 326 ? 126.935 130.290 92.787  1.00 90.26  ? 326 LEU B CG  1 
ATOM 3563 C CD1 . LEU B 1 326 ? 128.412 130.571 92.646  1.00 91.71  ? 326 LEU B CD1 1 
ATOM 3564 C CD2 . LEU B 1 326 ? 126.706 128.884 93.287  1.00 91.85  ? 326 LEU B CD2 1 
ATOM 3565 N N   . THR B 1 327 ? 124.397 132.908 95.659  1.00 96.27  ? 327 THR B N   1 
ATOM 3566 C CA  . THR B 1 327 ? 124.173 133.735 96.835  1.00 98.85  ? 327 THR B CA  1 
ATOM 3567 C C   . THR B 1 327 ? 123.004 134.663 96.515  1.00 100.70 ? 327 THR B C   1 
ATOM 3568 O O   . THR B 1 327 ? 122.272 134.440 95.546  1.00 102.00 ? 327 THR B O   1 
ATOM 3569 C CB  . THR B 1 327 ? 125.470 134.470 97.222  1.00 100.09 ? 327 THR B CB  1 
ATOM 3570 O OG1 . THR B 1 327 ? 125.263 135.238 98.413  1.00 108.33 ? 327 THR B OG1 1 
ATOM 3571 C CG2 . THR B 1 327 ? 125.910 135.394 96.105  1.00 98.53  ? 327 THR B CG2 1 
ATOM 3572 N N   . LEU B 1 328 ? 122.819 135.703 97.330  1.00 101.85 ? 328 LEU B N   1 
ATOM 3573 C CA  . LEU B 1 328 ? 121.678 136.594 97.143  1.00 104.45 ? 328 LEU B CA  1 
ATOM 3574 C C   . LEU B 1 328 ? 121.740 137.307 95.799  1.00 104.81 ? 328 LEU B C   1 
ATOM 3575 O O   . LEU B 1 328 ? 120.716 137.464 95.125  1.00 108.41 ? 328 LEU B O   1 
ATOM 3576 C CB  . LEU B 1 328 ? 121.614 137.609 98.283  1.00 109.12 ? 328 LEU B CB  1 
ATOM 3577 C CG  . LEU B 1 328 ? 120.717 137.253 99.468  1.00 113.33 ? 328 LEU B CG  1 
ATOM 3578 C CD1 . LEU B 1 328 ? 119.308 136.947 98.995  1.00 110.76 ? 328 LEU B CD1 1 
ATOM 3579 C CD2 . LEU B 1 328 ? 121.289 136.087 100.251 1.00 109.30 ? 328 LEU B CD2 1 
ATOM 3580 N N   . THR B 1 329 ? 122.927 137.747 95.391  1.00 99.92  ? 329 THR B N   1 
ATOM 3581 C CA  . THR B 1 329 ? 123.073 138.561 94.194  1.00 101.87 ? 329 THR B CA  1 
ATOM 3582 C C   . THR B 1 329 ? 123.623 137.799 92.995  1.00 104.53 ? 329 THR B C   1 
ATOM 3583 O O   . THR B 1 329 ? 123.663 138.362 91.896  1.00 105.82 ? 329 THR B O   1 
ATOM 3584 C CB  . THR B 1 329 ? 123.983 139.760 94.481  1.00 109.13 ? 329 THR B CB  1 
ATOM 3585 O OG1 . THR B 1 329 ? 125.348 139.387 94.262  1.00 112.80 ? 329 THR B OG1 1 
ATOM 3586 C CG2 . THR B 1 329 ? 123.816 140.214 95.920  1.00 110.13 ? 329 THR B CG2 1 
ATOM 3587 N N   . TYR B 1 330 ? 124.046 136.551 93.168  1.00 101.74 ? 330 TYR B N   1 
ATOM 3588 C CA  . TYR B 1 330 ? 124.637 135.766 92.091  1.00 95.09  ? 330 TYR B CA  1 
ATOM 3589 C C   . TYR B 1 330 ? 123.625 134.726 91.633  1.00 91.75  ? 330 TYR B C   1 
ATOM 3590 O O   . TYR B 1 330 ? 123.208 133.874 92.423  1.00 94.90  ? 330 TYR B O   1 
ATOM 3591 C CB  . TYR B 1 330 ? 125.925 135.089 92.554  1.00 93.76  ? 330 TYR B CB  1 
ATOM 3592 C CG  . TYR B 1 330 ? 126.873 134.725 91.440  1.00 96.26  ? 330 TYR B CG  1 
ATOM 3593 C CD1 . TYR B 1 330 ? 127.593 135.700 90.770  1.00 102.19 ? 330 TYR B CD1 1 
ATOM 3594 C CD2 . TYR B 1 330 ? 127.038 133.408 91.048  1.00 97.82  ? 330 TYR B CD2 1 
ATOM 3595 C CE1 . TYR B 1 330 ? 128.464 135.370 89.754  1.00 104.87 ? 330 TYR B CE1 1 
ATOM 3596 C CE2 . TYR B 1 330 ? 127.901 133.069 90.031  1.00 103.99 ? 330 TYR B CE2 1 
ATOM 3597 C CZ  . TYR B 1 330 ? 128.610 134.053 89.385  1.00 107.27 ? 330 TYR B CZ  1 
ATOM 3598 O OH  . TYR B 1 330 ? 129.471 133.716 88.369  1.00 110.49 ? 330 TYR B OH  1 
ATOM 3599 N N   . HIS B 1 331 ? 123.243 134.787 90.362  1.00 87.56  ? 331 HIS B N   1 
ATOM 3600 C CA  . HIS B 1 331 ? 122.253 133.884 89.798  1.00 83.21  ? 331 HIS B CA  1 
ATOM 3601 C C   . HIS B 1 331 ? 122.835 133.182 88.582  1.00 84.88  ? 331 HIS B C   1 
ATOM 3602 O O   . HIS B 1 331 ? 123.571 133.788 87.800  1.00 91.70  ? 331 HIS B O   1 
ATOM 3603 C CB  . HIS B 1 331 ? 120.981 134.630 89.400  1.00 85.37  ? 331 HIS B CB  1 
ATOM 3604 C CG  . HIS B 1 331 ? 120.288 135.300 90.543  1.00 90.19  ? 331 HIS B CG  1 
ATOM 3605 N ND1 . HIS B 1 331 ? 120.516 134.957 91.857  1.00 92.34  ? 331 HIS B ND1 1 
ATOM 3606 C CD2 . HIS B 1 331 ? 119.370 136.293 90.568  1.00 95.28  ? 331 HIS B CD2 1 
ATOM 3607 C CE1 . HIS B 1 331 ? 119.771 135.711 92.643  1.00 95.49  ? 331 HIS B CE1 1 
ATOM 3608 N NE2 . HIS B 1 331 ? 119.064 136.529 91.886  1.00 99.57  ? 331 HIS B NE2 1 
ATOM 3609 N N   . VAL B 1 332 ? 122.498 131.901 88.428  1.00 75.50  ? 332 VAL B N   1 
ATOM 3610 C CA  . VAL B 1 332 ? 122.955 131.085 87.312  1.00 71.34  ? 332 VAL B CA  1 
ATOM 3611 C C   . VAL B 1 332 ? 121.734 130.459 86.653  1.00 70.63  ? 332 VAL B C   1 
ATOM 3612 O O   . VAL B 1 332 ? 120.680 130.304 87.269  1.00 75.51  ? 332 VAL B O   1 
ATOM 3613 C CB  . VAL B 1 332 ? 123.950 129.993 87.757  1.00 72.90  ? 332 VAL B CB  1 
ATOM 3614 C CG1 . VAL B 1 332 ? 124.785 129.518 86.587  1.00 78.47  ? 332 VAL B CG1 1 
ATOM 3615 C CG2 . VAL B 1 332 ? 124.842 130.503 88.870  1.00 77.33  ? 332 VAL B CG2 1 
ATOM 3616 N N   . ALA B 1 333 ? 121.883 130.103 85.378  1.00 69.16  ? 333 ALA B N   1 
ATOM 3617 C CA  . ALA B 1 333 ? 120.783 129.512 84.632  1.00 69.20  ? 333 ALA B CA  1 
ATOM 3618 C C   . ALA B 1 333 ? 121.318 128.531 83.600  1.00 76.46  ? 333 ALA B C   1 
ATOM 3619 O O   . ALA B 1 333 ? 122.472 128.611 83.175  1.00 82.47  ? 333 ALA B O   1 
ATOM 3620 C CB  . ALA B 1 333 ? 119.932 130.582 83.945  1.00 70.02  ? 333 ALA B CB  1 
ATOM 3621 N N   . SER B 1 334 ? 120.453 127.602 83.200  1.00 72.20  ? 334 SER B N   1 
ATOM 3622 C CA  . SER B 1 334 ? 120.761 126.629 82.162  1.00 64.87  ? 334 SER B CA  1 
ATOM 3623 C C   . SER B 1 334 ? 119.469 126.266 81.449  1.00 69.12  ? 334 SER B C   1 
ATOM 3624 O O   . SER B 1 334 ? 118.377 126.419 81.996  1.00 82.91  ? 334 SER B O   1 
ATOM 3625 C CB  . SER B 1 334 ? 121.419 125.373 82.735  1.00 70.75  ? 334 SER B CB  1 
ATOM 3626 O OG  . SER B 1 334 ? 122.453 125.706 83.640  1.00 84.26  ? 334 SER B OG  1 
ATOM 3627 N N   . ALA B 1 335 ? 119.601 125.779 80.221  1.00 64.46  ? 335 ALA B N   1 
ATOM 3628 C CA  . ALA B 1 335 ? 118.429 125.456 79.423  1.00 68.32  ? 335 ALA B CA  1 
ATOM 3629 C C   . ALA B 1 335 ? 118.829 124.493 78.318  1.00 77.15  ? 335 ALA B C   1 
ATOM 3630 O O   . ALA B 1 335 ? 120.011 124.242 78.081  1.00 80.42  ? 335 ALA B O   1 
ATOM 3631 C CB  . ALA B 1 335 ? 117.786 126.715 78.844  1.00 69.03  ? 335 ALA B CB  1 
ATOM 3632 N N   . HIS B 1 336 ? 117.819 123.957 77.641  1.00 78.65  ? 336 HIS B N   1 
ATOM 3633 C CA  . HIS B 1 336 ? 117.984 122.981 76.571  1.00 81.57  ? 336 HIS B CA  1 
ATOM 3634 C C   . HIS B 1 336 ? 117.126 123.359 75.374  1.00 82.76  ? 336 HIS B C   1 
ATOM 3635 O O   . HIS B 1 336 ? 116.362 122.549 74.848  1.00 92.51  ? 336 HIS B O   1 
ATOM 3636 C CB  . HIS B 1 336 ? 117.631 121.580 77.050  1.00 90.83  ? 336 HIS B CB  1 
ATOM 3637 C CG  . HIS B 1 336 ? 118.744 120.884 77.765  1.00 90.04  ? 336 HIS B CG  1 
ATOM 3638 N ND1 . HIS B 1 336 ? 119.157 119.612 77.435  1.00 88.28  ? 336 HIS B ND1 1 
ATOM 3639 C CD2 . HIS B 1 336 ? 119.521 121.275 78.801  1.00 87.68  ? 336 HIS B CD2 1 
ATOM 3640 C CE1 . HIS B 1 336 ? 120.146 119.254 78.233  1.00 89.42  ? 336 HIS B CE1 1 
ATOM 3641 N NE2 . HIS B 1 336 ? 120.386 120.245 79.071  1.00 87.78  ? 336 HIS B NE2 1 
ATOM 3642 N N   . LEU B 1 337 ? 117.231 124.612 74.939  1.00 79.00  ? 337 LEU B N   1 
ATOM 3643 C CA  . LEU B 1 337 ? 116.381 125.115 73.867  1.00 90.43  ? 337 LEU B CA  1 
ATOM 3644 C C   . LEU B 1 337 ? 116.508 124.258 72.615  1.00 93.41  ? 337 LEU B C   1 
ATOM 3645 O O   . LEU B 1 337 ? 117.607 123.867 72.220  1.00 95.17  ? 337 LEU B O   1 
ATOM 3646 C CB  . LEU B 1 337 ? 116.749 126.560 73.537  1.00 88.82  ? 337 LEU B CB  1 
ATOM 3647 C CG  . LEU B 1 337 ? 117.276 127.416 74.685  1.00 84.92  ? 337 LEU B CG  1 
ATOM 3648 C CD1 . LEU B 1 337 ? 117.860 128.705 74.146  1.00 79.35  ? 337 LEU B CD1 1 
ATOM 3649 C CD2 . LEU B 1 337 ? 116.169 127.703 75.672  1.00 90.38  ? 337 LEU B CD2 1 
ATOM 3650 N N   . ALA B 1 338 ? 115.369 123.960 71.997  1.00 92.92  ? 338 ALA B N   1 
ATOM 3651 C CA  . ALA B 1 338 ? 115.310 123.205 70.749  1.00 96.03  ? 338 ALA B CA  1 
ATOM 3652 C C   . ALA B 1 338 ? 114.752 124.118 69.668  1.00 103.73 ? 338 ALA B C   1 
ATOM 3653 O O   . ALA B 1 338 ? 113.571 124.477 69.706  1.00 111.26 ? 338 ALA B O   1 
ATOM 3654 C CB  . ALA B 1 338 ? 114.453 121.952 70.906  1.00 103.12 ? 338 ALA B CB  1 
ATOM 3655 N N   . ILE B 1 339 ? 115.591 124.486 68.702  1.00 108.82 ? 339 ILE B N   1 
ATOM 3656 C CA  . ILE B 1 339 ? 115.195 125.443 67.677  1.00 116.19 ? 339 ILE B CA  1 
ATOM 3657 C C   . ILE B 1 339 ? 114.519 124.724 66.519  1.00 122.55 ? 339 ILE B C   1 
ATOM 3658 O O   . ILE B 1 339 ? 114.628 123.501 66.381  1.00 123.12 ? 339 ILE B O   1 
ATOM 3659 C CB  . ILE B 1 339 ? 116.395 126.255 67.165  1.00 113.90 ? 339 ILE B CB  1 
ATOM 3660 C CG1 . ILE B 1 339 ? 117.363 125.345 66.407  1.00 115.70 ? 339 ILE B CG1 1 
ATOM 3661 C CG2 . ILE B 1 339 ? 117.096 126.941 68.323  1.00 110.92 ? 339 ILE B CG2 1 
ATOM 3662 C CD1 . ILE B 1 339 ? 118.759 125.896 66.283  1.00 117.89 ? 339 ILE B CD1 1 
ATOM 3663 N N   . ASP B 1 340 ? 113.817 125.488 65.687  1.00 126.67 ? 340 ASP B N   1 
ATOM 3664 C CA  . ASP B 1 340 ? 113.261 124.981 64.444  1.00 134.68 ? 340 ASP B CA  1 
ATOM 3665 C C   . ASP B 1 340 ? 114.398 124.843 63.436  1.00 139.70 ? 340 ASP B C   1 
ATOM 3666 O O   . ASP B 1 340 ? 115.333 125.647 63.416  1.00 139.78 ? 340 ASP B O   1 
ATOM 3667 C CB  . ASP B 1 340 ? 112.132 125.922 63.969  1.00 136.85 ? 340 ASP B CB  1 
ATOM 3668 C CG  . ASP B 1 340 ? 111.652 125.672 62.530  1.00 145.10 ? 340 ASP B CG  1 
ATOM 3669 O OD1 . ASP B 1 340 ? 110.438 125.841 62.298  1.00 146.65 ? 340 ASP B OD1 1 
ATOM 3670 O OD2 . ASP B 1 340 ? 112.441 125.384 61.615  1.00 146.73 ? 340 ASP B OD2 1 
ATOM 3671 N N   . SER B 1 341 ? 114.320 123.794 62.612  1.00 143.67 ? 341 SER B N   1 
ATOM 3672 C CA  . SER B 1 341 ? 115.431 123.439 61.731  1.00 144.44 ? 341 SER B CA  1 
ATOM 3673 C C   . SER B 1 341 ? 115.905 124.619 60.889  1.00 146.00 ? 341 SER B C   1 
ATOM 3674 O O   . SER B 1 341 ? 117.110 124.789 60.669  1.00 147.06 ? 341 SER B O   1 
ATOM 3675 C CB  . SER B 1 341 ? 115.023 122.276 60.829  1.00 146.19 ? 341 SER B CB  1 
ATOM 3676 O OG  . SER B 1 341 ? 113.967 122.662 59.969  1.00 147.81 ? 341 SER B OG  1 
ATOM 3677 N N   . THR B 1 342 ? 114.978 125.445 60.410  1.00 146.94 ? 342 THR B N   1 
ATOM 3678 C CA  . THR B 1 342 ? 115.326 126.609 59.592  1.00 149.21 ? 342 THR B CA  1 
ATOM 3679 C C   . THR B 1 342 ? 115.616 127.811 60.498  1.00 148.32 ? 342 THR B C   1 
ATOM 3680 O O   . THR B 1 342 ? 114.895 128.809 60.550  1.00 145.19 ? 342 THR B O   1 
ATOM 3681 C CB  . THR B 1 342 ? 114.231 126.875 58.560  1.00 149.92 ? 342 THR B CB  1 
ATOM 3682 O OG1 . THR B 1 342 ? 113.201 127.715 59.099  1.00 152.16 ? 342 THR B OG1 1 
ATOM 3683 C CG2 . THR B 1 342 ? 113.612 125.565 58.097  1.00 147.44 ? 342 THR B CG2 1 
ATOM 3684 N N   . ALA B 1 343 ? 116.726 127.697 61.225  1.00 145.82 ? 343 ALA B N   1 
ATOM 3685 C CA  . ALA B 1 343 ? 117.163 128.756 62.123  1.00 140.40 ? 343 ALA B CA  1 
ATOM 3686 C C   . ALA B 1 343 ? 118.680 128.729 62.233  1.00 136.17 ? 343 ALA B C   1 
ATOM 3687 O O   . ALA B 1 343 ? 119.333 127.747 61.869  1.00 135.26 ? 343 ALA B O   1 
ATOM 3688 C CB  . ALA B 1 343 ? 116.528 128.622 63.512  1.00 135.66 ? 343 ALA B CB  1 
ATOM 3689 N N   . ASP B 1 344 ? 119.234 129.829 62.744  1.00 136.34 ? 344 ASP B N   1 
ATOM 3690 C CA  . ASP B 1 344 ? 120.675 129.972 62.881  1.00 133.87 ? 344 ASP B CA  1 
ATOM 3691 C C   . ASP B 1 344 ? 120.984 129.775 64.358  1.00 128.90 ? 344 ASP B C   1 
ATOM 3692 O O   . ASP B 1 344 ? 120.650 130.648 65.172  1.00 127.76 ? 344 ASP B O   1 
ATOM 3693 C CB  . ASP B 1 344 ? 121.125 131.357 62.386  1.00 136.52 ? 344 ASP B CB  1 
ATOM 3694 C CG  . ASP B 1 344 ? 122.504 131.809 62.909  1.00 138.19 ? 344 ASP B CG  1 
ATOM 3695 O OD1 . ASP B 1 344 ? 122.999 132.832 62.387  1.00 142.60 ? 344 ASP B OD1 1 
ATOM 3696 O OD2 . ASP B 1 344 ? 123.133 131.166 63.765  1.00 133.04 ? 344 ASP B OD2 1 
ATOM 3697 N N   . PRO B 1 345 ? 121.602 128.657 64.751  1.00 125.41 ? 345 PRO B N   1 
ATOM 3698 C CA  . PRO B 1 345 ? 121.810 128.399 66.187  1.00 123.22 ? 345 PRO B CA  1 
ATOM 3699 C C   . PRO B 1 345 ? 122.628 129.459 66.899  1.00 123.37 ? 345 PRO B C   1 
ATOM 3700 O O   . PRO B 1 345 ? 122.330 129.784 68.053  1.00 122.78 ? 345 PRO B O   1 
ATOM 3701 C CB  . PRO B 1 345 ? 122.519 127.038 66.190  1.00 121.69 ? 345 PRO B CB  1 
ATOM 3702 C CG  . PRO B 1 345 ? 122.174 126.420 64.874  1.00 122.04 ? 345 PRO B CG  1 
ATOM 3703 C CD  . PRO B 1 345 ? 122.081 127.550 63.908  1.00 123.40 ? 345 PRO B CD  1 
ATOM 3704 N N   . GLU B 1 346 ? 123.652 130.010 66.246  1.00 126.24 ? 346 GLU B N   1 
ATOM 3705 C CA  . GLU B 1 346 ? 124.496 131.005 66.901  1.00 129.56 ? 346 GLU B CA  1 
ATOM 3706 C C   . GLU B 1 346 ? 123.712 132.273 67.216  1.00 125.65 ? 346 GLU B C   1 
ATOM 3707 O O   . GLU B 1 346 ? 123.802 132.814 68.325  1.00 120.61 ? 346 GLU B O   1 
ATOM 3708 C CB  . GLU B 1 346 ? 125.706 131.324 66.023  1.00 133.05 ? 346 GLU B CB  1 
ATOM 3709 C CG  . GLU B 1 346 ? 126.948 130.517 66.362  1.00 135.84 ? 346 GLU B CG  1 
ATOM 3710 C CD  . GLU B 1 346 ? 126.974 129.171 65.667  1.00 138.13 ? 346 GLU B CD  1 
ATOM 3711 O OE1 . GLU B 1 346 ? 126.990 129.146 64.419  1.00 142.30 ? 346 GLU B OE1 1 
ATOM 3712 O OE2 . GLU B 1 346 ? 126.981 128.137 66.366  1.00 135.21 ? 346 GLU B OE2 1 
ATOM 3713 N N   . ALA B 1 347 ? 122.936 132.764 66.246  1.00 127.17 ? 347 ALA B N   1 
ATOM 3714 C CA  . ALA B 1 347 ? 122.144 133.967 66.473  1.00 122.51 ? 347 ALA B CA  1 
ATOM 3715 C C   . ALA B 1 347 ? 121.103 133.744 67.561  1.00 118.84 ? 347 ALA B C   1 
ATOM 3716 O O   . ALA B 1 347 ? 120.904 134.606 68.425  1.00 119.28 ? 347 ALA B O   1 
ATOM 3717 C CB  . ALA B 1 347 ? 121.473 134.408 65.172  1.00 117.25 ? 347 ALA B CB  1 
ATOM 3718 N N   . VAL B 1 348 ? 120.435 132.590 67.536  1.00 117.66 ? 348 VAL B N   1 
ATOM 3719 C CA  . VAL B 1 348 ? 119.430 132.281 68.549  1.00 111.69 ? 348 VAL B CA  1 
ATOM 3720 C C   . VAL B 1 348 ? 120.068 132.241 69.930  1.00 110.46 ? 348 VAL B C   1 
ATOM 3721 O O   . VAL B 1 348 ? 119.542 132.807 70.896  1.00 113.08 ? 348 VAL B O   1 
ATOM 3722 C CB  . VAL B 1 348 ? 118.728 130.953 68.216  1.00 107.79 ? 348 VAL B CB  1 
ATOM 3723 C CG1 . VAL B 1 348 ? 118.082 130.365 69.456  1.00 104.06 ? 348 VAL B CG1 1 
ATOM 3724 C CG2 . VAL B 1 348 ? 117.701 131.158 67.120  1.00 111.50 ? 348 VAL B CG2 1 
ATOM 3725 N N   . LEU B 1 349 ? 121.217 131.575 70.039  1.00 109.38 ? 349 LEU B N   1 
ATOM 3726 C CA  . LEU B 1 349 ? 121.888 131.453 71.327  1.00 108.88 ? 349 LEU B CA  1 
ATOM 3727 C C   . LEU B 1 349 ? 122.310 132.822 71.844  1.00 111.89 ? 349 LEU B C   1 
ATOM 3728 O O   . LEU B 1 349 ? 122.097 133.147 73.018  1.00 113.66 ? 349 LEU B O   1 
ATOM 3729 C CB  . LEU B 1 349 ? 123.088 130.513 71.184  1.00 109.25 ? 349 LEU B CB  1 
ATOM 3730 C CG  . LEU B 1 349 ? 123.878 129.910 72.353  1.00 106.01 ? 349 LEU B CG  1 
ATOM 3731 C CD1 . LEU B 1 349 ? 125.055 129.139 71.783  1.00 104.20 ? 349 LEU B CD1 1 
ATOM 3732 C CD2 . LEU B 1 349 ? 124.369 130.916 73.381  1.00 105.07 ? 349 LEU B CD2 1 
ATOM 3733 N N   . ALA B 1 350 ? 122.905 133.642 70.974  1.00 113.61 ? 350 ALA B N   1 
ATOM 3734 C CA  . ALA B 1 350 ? 123.350 134.966 71.396  1.00 114.40 ? 350 ALA B CA  1 
ATOM 3735 C C   . ALA B 1 350 ? 122.175 135.829 71.828  1.00 114.58 ? 350 ALA B C   1 
ATOM 3736 O O   . ALA B 1 350 ? 122.249 136.528 72.846  1.00 114.02 ? 350 ALA B O   1 
ATOM 3737 C CB  . ALA B 1 350 ? 124.127 135.642 70.268  1.00 111.99 ? 350 ALA B CB  1 
ATOM 3738 N N   . GLU B 1 351 ? 121.078 135.787 71.071  1.00 112.96 ? 351 GLU B N   1 
ATOM 3739 C CA  . GLU B 1 351 ? 119.916 136.599 71.406  1.00 110.62 ? 351 GLU B CA  1 
ATOM 3740 C C   . GLU B 1 351 ? 119.304 136.157 72.730  1.00 109.96 ? 351 GLU B C   1 
ATOM 3741 O O   . GLU B 1 351 ? 118.918 136.995 73.553  1.00 112.70 ? 351 GLU B O   1 
ATOM 3742 C CB  . GLU B 1 351 ? 118.894 136.522 70.270  1.00 108.86 ? 351 GLU B CB  1 
ATOM 3743 C CG  . GLU B 1 351 ? 117.452 136.857 70.627  1.00 114.53 ? 351 GLU B CG  1 
ATOM 3744 C CD  . GLU B 1 351 ? 117.245 138.290 71.107  1.00 123.13 ? 351 GLU B CD  1 
ATOM 3745 O OE1 . GLU B 1 351 ? 118.228 139.032 71.313  1.00 126.60 ? 351 GLU B OE1 1 
ATOM 3746 O OE2 . GLU B 1 351 ? 116.074 138.690 71.252  1.00 121.01 ? 351 GLU B OE2 1 
ATOM 3747 N N   . ALA B 1 352 ? 119.224 134.844 72.961  1.00 107.68 ? 352 ALA B N   1 
ATOM 3748 C CA  . ALA B 1 352 ? 118.683 134.349 74.222  1.00 103.11 ? 352 ALA B CA  1 
ATOM 3749 C C   . ALA B 1 352 ? 119.566 134.740 75.400  1.00 104.52 ? 352 ALA B C   1 
ATOM 3750 O O   . ALA B 1 352 ? 119.061 135.133 76.459  1.00 107.96 ? 352 ALA B O   1 
ATOM 3751 C CB  . ALA B 1 352 ? 118.512 132.833 74.159  1.00 96.65  ? 352 ALA B CB  1 
ATOM 3752 N N   . SER B 1 353 ? 120.888 134.635 75.241  1.00 103.59 ? 353 SER B N   1 
ATOM 3753 C CA  . SER B 1 353 ? 121.777 135.017 76.334  1.00 104.41 ? 353 SER B CA  1 
ATOM 3754 C C   . SER B 1 353 ? 121.670 136.506 76.631  1.00 108.99 ? 353 SER B C   1 
ATOM 3755 O O   . SER B 1 353 ? 121.662 136.914 77.800  1.00 113.22 ? 353 SER B O   1 
ATOM 3756 C CB  . SER B 1 353 ? 123.222 134.642 76.010  1.00 111.00 ? 353 SER B CB  1 
ATOM 3757 O OG  . SER B 1 353 ? 123.494 134.775 74.630  1.00 114.66 ? 353 SER B OG  1 
ATOM 3758 N N   . SER B 1 354 ? 121.588 137.336 75.587  1.00 108.65 ? 354 SER B N   1 
ATOM 3759 C CA  . SER B 1 354 ? 121.441 138.770 75.812  1.00 110.19 ? 354 SER B CA  1 
ATOM 3760 C C   . SER B 1 354 ? 120.123 139.080 76.505  1.00 110.07 ? 354 SER B C   1 
ATOM 3761 O O   . SER B 1 354 ? 120.073 139.933 77.398  1.00 109.61 ? 354 SER B O   1 
ATOM 3762 C CB  . SER B 1 354 ? 121.547 139.536 74.494  1.00 108.81 ? 354 SER B CB  1 
ATOM 3763 O OG  . SER B 1 354 ? 120.917 138.842 73.439  1.00 107.58 ? 354 SER B OG  1 
ATOM 3764 N N   . ARG B 1 355 ? 119.043 138.400 76.111  1.00 108.07 ? 355 ARG B N   1 
ATOM 3765 C CA  . ARG B 1 355 ? 117.766 138.599 76.789  1.00 104.41 ? 355 ARG B CA  1 
ATOM 3766 C C   . ARG B 1 355 ? 117.864 138.238 78.263  1.00 105.62 ? 355 ARG B C   1 
ATOM 3767 O O   . ARG B 1 355 ? 117.402 138.990 79.127  1.00 112.48 ? 355 ARG B O   1 
ATOM 3768 C CB  . ARG B 1 355 ? 116.667 137.779 76.118  1.00 101.90 ? 355 ARG B CB  1 
ATOM 3769 C CG  . ARG B 1 355 ? 116.162 138.356 74.819  1.00 107.02 ? 355 ARG B CG  1 
ATOM 3770 C CD  . ARG B 1 355 ? 114.803 137.778 74.485  1.00 110.06 ? 355 ARG B CD  1 
ATOM 3771 N NE  . ARG B 1 355 ? 114.248 138.361 73.271  1.00 115.09 ? 355 ARG B NE  1 
ATOM 3772 C CZ  . ARG B 1 355 ? 113.099 137.994 72.722  1.00 115.61 ? 355 ARG B CZ  1 
ATOM 3773 N NH1 . ARG B 1 355 ? 112.349 137.047 73.258  1.00 114.14 ? 355 ARG B NH1 1 
ATOM 3774 N NH2 . ARG B 1 355 ? 112.694 138.592 71.606  1.00 114.93 ? 355 ARG B NH2 1 
ATOM 3775 N N   . LEU B 1 356 ? 118.461 137.086 78.572  1.00 103.32 ? 356 LEU B N   1 
ATOM 3776 C CA  . LEU B 1 356 ? 118.578 136.687 79.971  1.00 102.91 ? 356 LEU B CA  1 
ATOM 3777 C C   . LEU B 1 356 ? 119.384 137.708 80.760  1.00 104.50 ? 356 LEU B C   1 
ATOM 3778 O O   . LEU B 1 356 ? 118.967 138.145 81.840  1.00 104.73 ? 356 LEU B O   1 
ATOM 3779 C CB  . LEU B 1 356 ? 119.211 135.301 80.084  1.00 99.17  ? 356 LEU B CB  1 
ATOM 3780 C CG  . LEU B 1 356 ? 118.425 134.113 79.533  1.00 100.27 ? 356 LEU B CG  1 
ATOM 3781 C CD1 . LEU B 1 356 ? 119.115 132.816 79.901  1.00 94.46  ? 356 LEU B CD1 1 
ATOM 3782 C CD2 . LEU B 1 356 ? 117.005 134.123 80.057  1.00 98.80  ? 356 LEU B CD2 1 
ATOM 3783 N N   . TYR B 1 357 ? 120.528 138.130 80.216  1.00 106.98 ? 357 TYR B N   1 
ATOM 3784 C CA  . TYR B 1 357 ? 121.380 139.071 80.935  1.00 110.08 ? 357 TYR B CA  1 
ATOM 3785 C C   . TYR B 1 357 ? 120.679 140.406 81.147  1.00 112.58 ? 357 TYR B C   1 
ATOM 3786 O O   . TYR B 1 357 ? 120.744 140.982 82.239  1.00 114.94 ? 357 TYR B O   1 
ATOM 3787 C CB  . TYR B 1 357 ? 122.693 139.271 80.182  1.00 115.91 ? 357 TYR B CB  1 
ATOM 3788 C CG  . TYR B 1 357 ? 123.659 140.204 80.874  1.00 124.26 ? 357 TYR B CG  1 
ATOM 3789 C CD1 . TYR B 1 357 ? 124.508 141.022 80.143  1.00 128.68 ? 357 TYR B CD1 1 
ATOM 3790 C CD2 . TYR B 1 357 ? 123.739 140.251 82.260  1.00 122.22 ? 357 TYR B CD2 1 
ATOM 3791 C CE1 . TYR B 1 357 ? 125.395 141.872 80.772  1.00 133.41 ? 357 TYR B CE1 1 
ATOM 3792 C CE2 . TYR B 1 357 ? 124.621 141.095 82.896  1.00 129.18 ? 357 TYR B CE2 1 
ATOM 3793 C CZ  . TYR B 1 357 ? 125.448 141.903 82.148  1.00 138.11 ? 357 TYR B CZ  1 
ATOM 3794 O OH  . TYR B 1 357 ? 126.331 142.746 82.779  1.00 146.25 ? 357 TYR B OH  1 
ATOM 3795 N N   . SER B 1 358 ? 119.995 140.913 80.119  1.00 110.81 ? 358 SER B N   1 
ATOM 3796 C CA  . SER B 1 358 ? 119.398 142.239 80.218  1.00 108.95 ? 358 SER B CA  1 
ATOM 3797 C C   . SER B 1 358 ? 118.171 142.233 81.122  1.00 106.82 ? 358 SER B C   1 
ATOM 3798 O O   . SER B 1 358 ? 117.999 143.133 81.952  1.00 109.11 ? 358 SER B O   1 
ATOM 3799 C CB  . SER B 1 358 ? 119.048 142.761 78.825  1.00 107.53 ? 358 SER B CB  1 
ATOM 3800 O OG  . SER B 1 358 ? 117.695 142.505 78.499  1.00 105.36 ? 358 SER B OG  1 
ATOM 3801 N N   . ARG B 1 359 ? 117.307 141.224 80.988  1.00 103.81 ? 359 ARG B N   1 
ATOM 3802 C CA  . ARG B 1 359 ? 116.058 141.232 81.740  1.00 101.80 ? 359 ARG B CA  1 
ATOM 3803 C C   . ARG B 1 359 ? 116.256 140.759 83.174  1.00 103.88 ? 359 ARG B C   1 
ATOM 3804 O O   . ARG B 1 359 ? 115.791 141.409 84.116  1.00 105.51 ? 359 ARG B O   1 
ATOM 3805 C CB  . ARG B 1 359 ? 115.010 140.369 81.039  1.00 100.88 ? 359 ARG B CB  1 
ATOM 3806 C CG  . ARG B 1 359 ? 114.246 141.079 79.937  1.00 102.74 ? 359 ARG B CG  1 
ATOM 3807 C CD  . ARG B 1 359 ? 114.941 140.942 78.594  1.00 105.56 ? 359 ARG B CD  1 
ATOM 3808 N NE  . ARG B 1 359 ? 114.098 141.264 77.445  1.00 111.63 ? 359 ARG B NE  1 
ATOM 3809 C CZ  . ARG B 1 359 ? 112.898 140.752 77.194  1.00 111.92 ? 359 ARG B CZ  1 
ATOM 3810 N NH1 . ARG B 1 359 ? 112.366 139.811 77.957  1.00 106.16 ? 359 ARG B NH1 1 
ATOM 3811 N NH2 . ARG B 1 359 ? 112.224 141.178 76.131  1.00 114.08 ? 359 ARG B NH2 1 
ATOM 3812 N N   . PHE B 1 360 ? 116.935 139.628 83.366  1.00 99.07  ? 360 PHE B N   1 
ATOM 3813 C CA  . PHE B 1 360 ? 116.987 138.996 84.673  1.00 94.80  ? 360 PHE B CA  1 
ATOM 3814 C C   . PHE B 1 360 ? 118.341 139.102 85.355  1.00 94.14  ? 360 PHE B C   1 
ATOM 3815 O O   . PHE B 1 360 ? 118.461 138.694 86.515  1.00 92.30  ? 360 PHE B O   1 
ATOM 3816 C CB  . PHE B 1 360 ? 116.585 137.522 84.553  1.00 92.86  ? 360 PHE B CB  1 
ATOM 3817 C CG  . PHE B 1 360 ? 115.252 137.319 83.902  1.00 91.53  ? 360 PHE B CG  1 
ATOM 3818 C CD1 . PHE B 1 360 ? 114.092 137.351 84.651  1.00 95.04  ? 360 PHE B CD1 1 
ATOM 3819 C CD2 . PHE B 1 360 ? 115.157 137.116 82.539  1.00 92.02  ? 360 PHE B CD2 1 
ATOM 3820 C CE1 . PHE B 1 360 ? 112.865 137.172 84.054  1.00 96.76  ? 360 PHE B CE1 1 
ATOM 3821 C CE2 . PHE B 1 360 ? 113.933 136.939 81.937  1.00 95.19  ? 360 PHE B CE2 1 
ATOM 3822 C CZ  . PHE B 1 360 ? 112.785 136.965 82.695  1.00 97.85  ? 360 PHE B CZ  1 
ATOM 3823 N N   . GLY B 1 361 ? 119.352 139.637 84.680  1.00 98.98  ? 361 GLY B N   1 
ATOM 3824 C CA  . GLY B 1 361 ? 120.646 139.817 85.316  1.00 104.74 ? 361 GLY B CA  1 
ATOM 3825 C C   . GLY B 1 361 ? 121.301 138.523 85.742  1.00 101.70 ? 361 GLY B C   1 
ATOM 3826 O O   . GLY B 1 361 ? 121.856 138.442 86.845  1.00 101.87 ? 361 GLY B O   1 
ATOM 3827 N N   . PHE B 1 362 ? 121.238 137.500 84.898  1.00 101.27 ? 362 PHE B N   1 
ATOM 3828 C CA  . PHE B 1 362 ? 121.879 136.231 85.203  1.00 92.17  ? 362 PHE B CA  1 
ATOM 3829 C C   . PHE B 1 362 ? 123.377 136.347 84.968  1.00 94.91  ? 362 PHE B C   1 
ATOM 3830 O O   . PHE B 1 362 ? 123.815 136.743 83.885  1.00 102.61 ? 362 PHE B O   1 
ATOM 3831 C CB  . PHE B 1 362 ? 121.287 135.116 84.347  1.00 84.45  ? 362 PHE B CB  1 
ATOM 3832 C CG  . PHE B 1 362 ? 119.991 134.583 84.869  1.00 81.37  ? 362 PHE B CG  1 
ATOM 3833 C CD1 . PHE B 1 362 ? 119.915 134.041 86.136  1.00 76.05  ? 362 PHE B CD1 1 
ATOM 3834 C CD2 . PHE B 1 362 ? 118.849 134.624 84.095  1.00 88.77  ? 362 PHE B CD2 1 
ATOM 3835 C CE1 . PHE B 1 362 ? 118.726 133.552 86.623  1.00 73.25  ? 362 PHE B CE1 1 
ATOM 3836 C CE2 . PHE B 1 362 ? 117.657 134.134 84.578  1.00 84.78  ? 362 PHE B CE2 1 
ATOM 3837 C CZ  . PHE B 1 362 ? 117.597 133.598 85.843  1.00 73.39  ? 362 PHE B CZ  1 
ATOM 3838 N N   . SER B 1 363 ? 124.160 136.009 85.992  1.00 86.78  ? 363 SER B N   1 
ATOM 3839 C CA  . SER B 1 363 ? 125.611 136.088 85.866  1.00 89.81  ? 363 SER B CA  1 
ATOM 3840 C C   . SER B 1 363 ? 126.132 135.104 84.828  1.00 93.72  ? 363 SER B C   1 
ATOM 3841 O O   . SER B 1 363 ? 127.018 135.439 84.035  1.00 101.26 ? 363 SER B O   1 
ATOM 3842 C CB  . SER B 1 363 ? 126.263 135.835 87.221  1.00 93.21  ? 363 SER B CB  1 
ATOM 3843 O OG  . SER B 1 363 ? 125.744 136.710 88.204  1.00 100.85 ? 363 SER B OG  1 
ATOM 3844 N N   . SER B 1 364 ? 125.592 133.888 84.812  1.00 88.02  ? 364 SER B N   1 
ATOM 3845 C CA  . SER B 1 364 ? 126.006 132.864 83.868  1.00 86.70  ? 364 SER B CA  1 
ATOM 3846 C C   . SER B 1 364 ? 124.780 132.265 83.200  1.00 85.46  ? 364 SER B C   1 
ATOM 3847 O O   . SER B 1 364 ? 123.708 132.176 83.800  1.00 88.20  ? 364 SER B O   1 
ATOM 3848 C CB  . SER B 1 364 ? 126.815 131.761 84.554  1.00 89.58  ? 364 SER B CB  1 
ATOM 3849 O OG  . SER B 1 364 ? 127.916 132.302 85.259  1.00 106.41 ? 364 SER B OG  1 
ATOM 3850 N N   . CYS B 1 365 ? 124.951 131.853 81.948  1.00 84.10  ? 365 CYS B N   1 
ATOM 3851 C CA  . CYS B 1 365 ? 123.854 131.274 81.181  1.00 80.92  ? 365 CYS B CA  1 
ATOM 3852 C C   . CYS B 1 365 ? 124.444 130.292 80.181  1.00 83.85  ? 365 CYS B C   1 
ATOM 3853 O O   . CYS B 1 365 ? 125.063 130.708 79.198  1.00 87.80  ? 365 CYS B O   1 
ATOM 3854 C CB  . CYS B 1 365 ? 123.046 132.357 80.474  1.00 83.23  ? 365 CYS B CB  1 
ATOM 3855 S SG  . CYS B 1 365 ? 124.039 133.668 79.737  1.00 100.43 ? 365 CYS B SG  1 
ATOM 3856 N N   . THR B 1 366 ? 124.254 129.001 80.433  1.00 75.81  ? 366 THR B N   1 
ATOM 3857 C CA  . THR B 1 366 ? 124.682 127.939 79.530  1.00 71.65  ? 366 THR B CA  1 
ATOM 3858 C C   . THR B 1 366 ? 123.441 127.347 78.878  1.00 72.21  ? 366 THR B C   1 
ATOM 3859 O O   . THR B 1 366 ? 122.672 126.638 79.531  1.00 81.56  ? 366 THR B O   1 
ATOM 3860 C CB  . THR B 1 366 ? 125.466 126.865 80.278  1.00 75.28  ? 366 THR B CB  1 
ATOM 3861 O OG1 . THR B 1 366 ? 126.538 127.475 81.005  1.00 86.46  ? 366 THR B OG1 1 
ATOM 3862 C CG2 . THR B 1 366 ? 126.036 125.860 79.304  1.00 74.74  ? 366 THR B CG2 1 
ATOM 3863 N N   . LEU B 1 367 ? 123.246 127.633 77.596  1.00 69.37  ? 367 LEU B N   1 
ATOM 3864 C CA  . LEU B 1 367 ? 122.055 127.208 76.868  1.00 69.80  ? 367 LEU B CA  1 
ATOM 3865 C C   . LEU B 1 367 ? 122.455 126.192 75.807  1.00 71.59  ? 367 LEU B C   1 
ATOM 3866 O O   . LEU B 1 367 ? 123.113 126.543 74.823  1.00 82.39  ? 367 LEU B O   1 
ATOM 3867 C CB  . LEU B 1 367 ? 121.354 128.405 76.233  1.00 73.15  ? 367 LEU B CB  1 
ATOM 3868 C CG  . LEU B 1 367 ? 121.217 129.655 77.099  1.00 75.82  ? 367 LEU B CG  1 
ATOM 3869 C CD1 . LEU B 1 367 ? 120.698 130.800 76.265  1.00 91.91  ? 367 LEU B CD1 1 
ATOM 3870 C CD2 . LEU B 1 367 ? 120.299 129.397 78.272  1.00 72.08  ? 367 LEU B CD2 1 
ATOM 3871 N N   . GLN B 1 368 ? 122.047 124.943 75.998  1.00 66.67  ? 368 GLN B N   1 
ATOM 3872 C CA  . GLN B 1 368 ? 122.291 123.905 75.006  1.00 72.90  ? 368 GLN B CA  1 
ATOM 3873 C C   . GLN B 1 368 ? 121.237 124.002 73.914  1.00 84.83  ? 368 GLN B C   1 
ATOM 3874 O O   . GLN B 1 368 ? 120.037 123.932 74.196  1.00 92.90  ? 368 GLN B O   1 
ATOM 3875 C CB  . GLN B 1 368 ? 122.266 122.526 75.657  1.00 76.39  ? 368 GLN B CB  1 
ATOM 3876 C CG  . GLN B 1 368 ? 122.693 121.406 74.735  1.00 76.97  ? 368 GLN B CG  1 
ATOM 3877 C CD  . GLN B 1 368 ? 122.403 120.038 75.310  1.00 85.71  ? 368 GLN B CD  1 
ATOM 3878 O OE1 . GLN B 1 368 ? 121.777 119.202 74.663  1.00 98.62  ? 368 GLN B OE1 1 
ATOM 3879 N NE2 . GLN B 1 368 ? 122.853 119.804 76.533  1.00 85.22  ? 368 GLN B NE2 1 
ATOM 3880 N N   . VAL B 1 369 ? 121.676 124.160 72.672  1.00 85.87  ? 369 VAL B N   1 
ATOM 3881 C CA  . VAL B 1 369 ? 120.776 124.363 71.543  1.00 90.55  ? 369 VAL B CA  1 
ATOM 3882 C C   . VAL B 1 369 ? 120.727 123.057 70.759  1.00 95.18  ? 369 VAL B C   1 
ATOM 3883 O O   . VAL B 1 369 ? 121.657 122.722 70.022  1.00 103.28 ? 369 VAL B O   1 
ATOM 3884 C CB  . VAL B 1 369 ? 121.222 125.535 70.669  1.00 94.63  ? 369 VAL B CB  1 
ATOM 3885 C CG1 . VAL B 1 369 ? 120.394 125.590 69.409  1.00 96.60  ? 369 VAL B CG1 1 
ATOM 3886 C CG2 . VAL B 1 369 ? 121.106 126.835 71.437  1.00 94.55  ? 369 VAL B CG2 1 
ATOM 3887 N N   . GLU B 1 370 ? 119.638 122.316 70.919  1.00 97.15  ? 370 GLU B N   1 
ATOM 3888 C CA  . GLU B 1 370 ? 119.430 121.068 70.204  1.00 103.46 ? 370 GLU B CA  1 
ATOM 3889 C C   . GLU B 1 370 ? 118.675 121.348 68.906  1.00 110.28 ? 370 GLU B C   1 
ATOM 3890 O O   . GLU B 1 370 ? 118.535 122.495 68.477  1.00 111.28 ? 370 GLU B O   1 
ATOM 3891 C CB  . GLU B 1 370 ? 118.690 120.068 71.088  1.00 104.28 ? 370 GLU B CB  1 
ATOM 3892 C CG  . GLU B 1 370 ? 119.158 120.046 72.530  1.00 102.95 ? 370 GLU B CG  1 
ATOM 3893 C CD  . GLU B 1 370 ? 118.231 119.254 73.426  1.00 104.54 ? 370 GLU B CD  1 
ATOM 3894 O OE1 . GLU B 1 370 ? 117.294 118.622 72.899  1.00 108.92 ? 370 GLU B OE1 1 
ATOM 3895 O OE2 . GLU B 1 370 ? 118.436 119.261 74.657  1.00 97.09  ? 370 GLU B OE2 1 
ATOM 3896 N N   . GLN B 1 371 ? 118.185 120.294 68.262  1.00 117.29 ? 371 GLN B N   1 
ATOM 3897 C CA  . GLN B 1 371 ? 117.420 120.406 67.030  1.00 122.79 ? 371 GLN B CA  1 
ATOM 3898 C C   . GLN B 1 371 ? 116.064 119.742 67.215  1.00 127.15 ? 371 GLN B C   1 
ATOM 3899 O O   . GLN B 1 371 ? 115.966 118.670 67.820  1.00 127.97 ? 371 GLN B O   1 
ATOM 3900 C CB  . GLN B 1 371 ? 118.165 119.761 65.856  1.00 123.27 ? 371 GLN B CB  1 
ATOM 3901 C CG  . GLN B 1 371 ? 117.683 120.188 64.475  1.00 124.50 ? 371 GLN B CG  1 
ATOM 3902 C CD  . GLN B 1 371 ? 118.193 121.557 64.049  1.00 132.45 ? 371 GLN B CD  1 
ATOM 3903 O OE1 . GLN B 1 371 ? 118.024 121.956 62.898  1.00 139.28 ? 371 GLN B OE1 1 
ATOM 3904 N NE2 . GLN B 1 371 ? 118.832 122.272 64.967  1.00 129.92 ? 371 GLN B NE2 1 
ATOM 3905 N N   . TYR B 1 372 ? 115.022 120.383 66.698  1.00 127.16 ? 372 TYR B N   1 
ATOM 3906 C CA  . TYR B 1 372 ? 113.668 119.862 66.833  1.00 129.97 ? 372 TYR B CA  1 
ATOM 3907 C C   . TYR B 1 372 ? 113.446 118.653 65.931  1.00 129.35 ? 372 TYR B C   1 
ATOM 3908 O O   . TYR B 1 372 ? 112.843 117.662 66.344  1.00 126.98 ? 372 TYR B O   1 
ATOM 3909 C CB  . TYR B 1 372 ? 112.640 120.948 66.514  1.00 129.64 ? 372 TYR B CB  1 
ATOM 3910 C CG  . TYR B 1 372 ? 111.329 120.769 67.241  1.00 132.42 ? 372 TYR B CG  1 
ATOM 3911 C CD1 . TYR B 1 372 ? 110.155 121.312 66.739  1.00 133.81 ? 372 TYR B CD1 1 
ATOM 3912 C CD2 . TYR B 1 372 ? 111.265 120.054 68.428  1.00 129.95 ? 372 TYR B CD2 1 
ATOM 3913 C CE1 . TYR B 1 372 ? 108.954 121.149 67.400  1.00 135.90 ? 372 TYR B CE1 1 
ATOM 3914 C CE2 . TYR B 1 372 ? 110.070 119.885 69.096  1.00 132.43 ? 372 TYR B CE2 1 
ATOM 3915 C CZ  . TYR B 1 372 ? 108.918 120.434 68.578  1.00 137.08 ? 372 TYR B CZ  1 
ATOM 3916 O OH  . TYR B 1 372 ? 107.724 120.268 69.242  1.00 137.08 ? 372 TYR B OH  1 
# 
